data_5J68 # _entry.id 5J68 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.284 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5J68 WWPDB D_1000220017 # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5J68 _pdbx_database_status.recvd_initial_deposition_date 2016-04-04 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBE _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Ni, T.' 1 'Harlos, K.' 2 'Gilbert, R.J.C.' 3 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country UK _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'Open Biology' _citation.journal_id_ASTM ? _citation.journal_id_CSD ? _citation.journal_id_ISSN 2046-2441 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 6 _citation.language ? _citation.page_first ? _citation.page_last ? _citation.title 'Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.' _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1098/rsob.160053 _citation.pdbx_database_id_PubMed 27249642 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Ni, T.' 1 primary 'Harlos, K.' 2 primary 'Gilbert, R.' 3 # _cell.angle_alpha 90.00 _cell.angle_alpha_esd ? _cell.angle_beta 90.00 _cell.angle_beta_esd ? _cell.angle_gamma 90.00 _cell.angle_gamma_esd ? _cell.entry_id 5J68 _cell.details ? _cell.formula_units_Z ? _cell.length_a 103.900 _cell.length_a_esd ? _cell.length_b 103.900 _cell.length_b_esd ? _cell.length_c 304.290 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 8 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 5J68 _symmetry.cell_setting ? _symmetry.Int_Tables_number 92 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'P 41 21 2' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Astrotactin-2 65054.977 1 ? ? ? ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 3 ? ? ? ? 3 non-polymer man BETA-D-MANNOSE 180.156 1 ? ? ? ? 4 non-polymer man ALPHA-D-MANNOSE 180.156 7 ? ? ? ? 5 non-polymer man D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE 420.096 1 ? ? ? ? # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;KFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDE AMGYPMVQQWRVRSNLYRVKLSTITLAAGFTNVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQ QLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEI NRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEW VDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKF TLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMAYNTLMEVSASMLFRVQHHYNSHYEKF GDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVETVPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVS MARNTYGESKGR ; _entity_poly.pdbx_seq_one_letter_code_can ;KFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDE AMGYPMVQQWRVRSNLYRVKLSTITLAAGFTNVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQ QLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEI NRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEW VDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKF TLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMAYNTLMEVSASMLFRVQHHYNSHYEKF GDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVETVPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVS MARNTYGESKGR ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 LYS n 1 2 PHE n 1 3 ASN n 1 4 ASP n 1 5 THR n 1 6 LEU n 1 7 PHE n 1 8 GLY n 1 9 GLU n 1 10 MET n 1 11 LEU n 1 12 HIS n 1 13 GLY n 1 14 TYR n 1 15 ASN n 1 16 ASN n 1 17 ARG n 1 18 THR n 1 19 GLN n 1 20 HIS n 1 21 VAL n 1 22 ASN n 1 23 GLN n 1 24 GLY n 1 25 GLN n 1 26 VAL n 1 27 PHE n 1 28 GLN n 1 29 MET n 1 30 THR n 1 31 PHE n 1 32 ARG n 1 33 GLU n 1 34 ASN n 1 35 ASN n 1 36 PHE n 1 37 ILE n 1 38 LYS n 1 39 ASP n 1 40 PHE n 1 41 PRO n 1 42 GLN n 1 43 LEU n 1 44 ALA n 1 45 ASP n 1 46 GLY n 1 47 LEU n 1 48 LEU n 1 49 VAL n 1 50 ILE n 1 51 PRO n 1 52 LEU n 1 53 PRO n 1 54 VAL n 1 55 GLU n 1 56 GLU n 1 57 GLN n 1 58 CYS n 1 59 ARG n 1 60 GLY n 1 61 VAL n 1 62 LEU n 1 63 SER n 1 64 GLU n 1 65 PRO n 1 66 LEU n 1 67 PRO n 1 68 ASP n 1 69 LEU n 1 70 GLN n 1 71 LEU n 1 72 LEU n 1 73 THR n 1 74 GLY n 1 75 ASP n 1 76 ILE n 1 77 ARG n 1 78 TYR n 1 79 ASP n 1 80 GLU n 1 81 ALA n 1 82 MET n 1 83 GLY n 1 84 TYR n 1 85 PRO n 1 86 MET n 1 87 VAL n 1 88 GLN n 1 89 GLN n 1 90 TRP n 1 91 ARG n 1 92 VAL n 1 93 ARG n 1 94 SER n 1 95 ASN n 1 96 LEU n 1 97 TYR n 1 98 ARG n 1 99 VAL n 1 100 LYS n 1 101 LEU n 1 102 SER n 1 103 THR n 1 104 ILE n 1 105 THR n 1 106 LEU n 1 107 ALA n 1 108 ALA n 1 109 GLY n 1 110 PHE n 1 111 THR n 1 112 ASN n 1 113 VAL n 1 114 LEU n 1 115 LYS n 1 116 ILE n 1 117 LEU n 1 118 THR n 1 119 LYS n 1 120 GLU n 1 121 SER n 1 122 SER n 1 123 ARG n 1 124 GLU n 1 125 GLU n 1 126 LEU n 1 127 LEU n 1 128 SER n 1 129 PHE n 1 130 ILE n 1 131 GLN n 1 132 HIS n 1 133 TYR n 1 134 GLY n 1 135 SER n 1 136 HIS n 1 137 TYR n 1 138 ILE n 1 139 ALA n 1 140 GLU n 1 141 ALA n 1 142 LEU n 1 143 TYR n 1 144 GLY n 1 145 SER n 1 146 GLU n 1 147 LEU n 1 148 THR n 1 149 CYS n 1 150 ILE n 1 151 ILE n 1 152 HIS n 1 153 PHE n 1 154 PRO n 1 155 SER n 1 156 LYS n 1 157 LYS n 1 158 VAL n 1 159 GLN n 1 160 GLN n 1 161 GLN n 1 162 LEU n 1 163 TRP n 1 164 LEU n 1 165 GLN n 1 166 TYR n 1 167 GLN n 1 168 LYS n 1 169 GLU n 1 170 THR n 1 171 THR n 1 172 GLU n 1 173 LEU n 1 174 GLY n 1 175 SER n 1 176 LYS n 1 177 LYS n 1 178 GLU n 1 179 LEU n 1 180 LYS n 1 181 SER n 1 182 MET n 1 183 PRO n 1 184 PHE n 1 185 ILE n 1 186 THR n 1 187 TYR n 1 188 LEU n 1 189 SER n 1 190 GLY n 1 191 LEU n 1 192 LEU n 1 193 THR n 1 194 ALA n 1 195 GLN n 1 196 MET n 1 197 LEU n 1 198 SER n 1 199 ASP n 1 200 ASP n 1 201 GLN n 1 202 LEU n 1 203 ILE n 1 204 SER n 1 205 GLY n 1 206 VAL n 1 207 GLU n 1 208 ILE n 1 209 ARG n 1 210 CYS n 1 211 GLU n 1 212 GLU n 1 213 LYS n 1 214 GLY n 1 215 ARG n 1 216 CYS n 1 217 PRO n 1 218 SER n 1 219 THR n 1 220 CYS n 1 221 HIS n 1 222 LEU n 1 223 CYS n 1 224 ARG n 1 225 ARG n 1 226 PRO n 1 227 GLY n 1 228 LYS n 1 229 GLU n 1 230 GLN n 1 231 LEU n 1 232 SER n 1 233 PRO n 1 234 THR n 1 235 PRO n 1 236 VAL n 1 237 LEU n 1 238 LEU n 1 239 GLU n 1 240 ILE n 1 241 ASN n 1 242 ARG n 1 243 VAL n 1 244 VAL n 1 245 PRO n 1 246 LEU n 1 247 TYR n 1 248 THR n 1 249 LEU n 1 250 ILE n 1 251 GLN n 1 252 ASP n 1 253 ASN n 1 254 GLY n 1 255 THR n 1 256 LYS n 1 257 GLU n 1 258 ALA n 1 259 PHE n 1 260 LYS n 1 261 SER n 1 262 ALA n 1 263 LEU n 1 264 MET n 1 265 SER n 1 266 SER n 1 267 TYR n 1 268 TRP n 1 269 CYS n 1 270 SER n 1 271 GLY n 1 272 LYS n 1 273 GLY n 1 274 ASP n 1 275 VAL n 1 276 ILE n 1 277 ASP n 1 278 ASP n 1 279 TRP n 1 280 CYS n 1 281 ARG n 1 282 CYS n 1 283 ASP n 1 284 LEU n 1 285 SER n 1 286 ALA n 1 287 PHE n 1 288 ASP n 1 289 ALA n 1 290 ASN n 1 291 GLY n 1 292 LEU n 1 293 PRO n 1 294 ASN n 1 295 CYS n 1 296 SER n 1 297 PRO n 1 298 LEU n 1 299 LEU n 1 300 GLN n 1 301 PRO n 1 302 VAL n 1 303 LEU n 1 304 ARG n 1 305 LEU n 1 306 SER n 1 307 PRO n 1 308 THR n 1 309 VAL n 1 310 GLU n 1 311 PRO n 1 312 SER n 1 313 SER n 1 314 THR n 1 315 VAL n 1 316 VAL n 1 317 SER n 1 318 LEU n 1 319 GLU n 1 320 TRP n 1 321 VAL n 1 322 ASP n 1 323 VAL n 1 324 GLN n 1 325 PRO n 1 326 ALA n 1 327 ILE n 1 328 GLY n 1 329 THR n 1 330 LYS n 1 331 VAL n 1 332 SER n 1 333 ASP n 1 334 TYR n 1 335 ILE n 1 336 LEU n 1 337 GLN n 1 338 HIS n 1 339 LYS n 1 340 LYS n 1 341 VAL n 1 342 ASP n 1 343 GLU n 1 344 TYR n 1 345 THR n 1 346 ASP n 1 347 THR n 1 348 ASP n 1 349 LEU n 1 350 TYR n 1 351 THR n 1 352 GLY n 1 353 GLU n 1 354 PHE n 1 355 LEU n 1 356 SER n 1 357 PHE n 1 358 ALA n 1 359 ASP n 1 360 ASP n 1 361 LEU n 1 362 LEU n 1 363 SER n 1 364 GLY n 1 365 LEU n 1 366 GLY n 1 367 THR n 1 368 SER n 1 369 CYS n 1 370 VAL n 1 371 ALA n 1 372 ALA n 1 373 GLY n 1 374 ARG n 1 375 SER n 1 376 HIS n 1 377 GLY n 1 378 GLU n 1 379 VAL n 1 380 PRO n 1 381 GLU n 1 382 VAL n 1 383 SER n 1 384 ILE n 1 385 TYR n 1 386 SER n 1 387 VAL n 1 388 ILE n 1 389 PHE n 1 390 LYS n 1 391 CYS n 1 392 LEU n 1 393 GLU n 1 394 PRO n 1 395 ASP n 1 396 GLY n 1 397 LEU n 1 398 TYR n 1 399 LYS n 1 400 PHE n 1 401 THR n 1 402 LEU n 1 403 TYR n 1 404 ALA n 1 405 VAL n 1 406 ASP n 1 407 THR n 1 408 ARG n 1 409 GLY n 1 410 ARG n 1 411 HIS n 1 412 SER n 1 413 GLU n 1 414 LEU n 1 415 SER n 1 416 THR n 1 417 VAL n 1 418 THR n 1 419 LEU n 1 420 ARG n 1 421 THR n 1 422 ALA n 1 423 CYS n 1 424 PRO n 1 425 LEU n 1 426 VAL n 1 427 ASP n 1 428 ASP n 1 429 ASN n 1 430 LYS n 1 431 ALA n 1 432 GLU n 1 433 GLU n 1 434 ILE n 1 435 ALA n 1 436 ASP n 1 437 LYS n 1 438 ILE n 1 439 TYR n 1 440 ASN n 1 441 LEU n 1 442 TYR n 1 443 ASN n 1 444 GLY n 1 445 TYR n 1 446 THR n 1 447 SER n 1 448 GLY n 1 449 LYS n 1 450 GLU n 1 451 GLN n 1 452 GLN n 1 453 MET n 1 454 ALA n 1 455 TYR n 1 456 ASN n 1 457 THR n 1 458 LEU n 1 459 MET n 1 460 GLU n 1 461 VAL n 1 462 SER n 1 463 ALA n 1 464 SER n 1 465 MET n 1 466 LEU n 1 467 PHE n 1 468 ARG n 1 469 VAL n 1 470 GLN n 1 471 HIS n 1 472 HIS n 1 473 TYR n 1 474 ASN n 1 475 SER n 1 476 HIS n 1 477 TYR n 1 478 GLU n 1 479 LYS n 1 480 PHE n 1 481 GLY n 1 482 ASP n 1 483 PHE n 1 484 VAL n 1 485 TRP n 1 486 ARG n 1 487 SER n 1 488 GLU n 1 489 ASP n 1 490 GLU n 1 491 LEU n 1 492 GLY n 1 493 PRO n 1 494 ARG n 1 495 LYS n 1 496 ALA n 1 497 HIS n 1 498 LEU n 1 499 ILE n 1 500 LEU n 1 501 ARG n 1 502 ARG n 1 503 LEU n 1 504 GLU n 1 505 ARG n 1 506 VAL n 1 507 SER n 1 508 SER n 1 509 HIS n 1 510 CYS n 1 511 SER n 1 512 SER n 1 513 LEU n 1 514 LEU n 1 515 ARG n 1 516 SER n 1 517 ALA n 1 518 TYR n 1 519 ILE n 1 520 GLN n 1 521 SER n 1 522 ARG n 1 523 VAL n 1 524 GLU n 1 525 THR n 1 526 VAL n 1 527 PRO n 1 528 TYR n 1 529 LEU n 1 530 PHE n 1 531 CYS n 1 532 ARG n 1 533 SER n 1 534 GLU n 1 535 GLU n 1 536 VAL n 1 537 ARG n 1 538 PRO n 1 539 ALA n 1 540 GLY n 1 541 MET n 1 542 VAL n 1 543 TRP n 1 544 TYR n 1 545 SER n 1 546 ILE n 1 547 LEU n 1 548 LYS n 1 549 ASP n 1 550 THR n 1 551 LYS n 1 552 ILE n 1 553 THR n 1 554 CYS n 1 555 GLU n 1 556 GLU n 1 557 LYS n 1 558 MET n 1 559 VAL n 1 560 SER n 1 561 MET n 1 562 ALA n 1 563 ARG n 1 564 ASN n 1 565 THR n 1 566 TYR n 1 567 GLY n 1 568 GLU n 1 569 SER n 1 570 LYS n 1 571 GLY n 1 572 ARG n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample 'Biological sequence' 1 572 Human ? 'ASTN2, KIAA0634' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK-293 ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample ? ? ? human ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK-293 ? ? ? ? ? ? ? ? ? ? ? ? 5 1 sample ? ? ? human ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK-293 ? ? ? ? ? ? ? ? ? ? ? ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code ASTN2_HUMAN _struct_ref.pdbx_db_accession O75129 _struct_ref.pdbx_db_isoform O75129-2 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;KFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDE AMGYPMVQQWRVRSNLYRVKLSTITLAAGFTNVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQ QLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEI NRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEW VDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKF TLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMAYNTLMEVSASMLFRVQHHYNSHYEKF GDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVETVPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVS MARNTYGESKGR ; _struct_ref.pdbx_align_begin 717 # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 5J68 _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 572 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession O75129 _struct_ref_seq.db_align_beg 717 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 1288 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 717 _struct_ref_seq.pdbx_auth_seq_align_end 1288 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 I3P non-polymer . D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE ? 'C6 H15 O15 P3' 420.096 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5J68 _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 6.31 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 80.51 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '0.1 M MES, pH 5.0 to 6.0, 5% PEG 6000' _exptl_crystal_grow.pdbx_pH_range 5-6 # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector PIXEL _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'DECTRIS PILATUS 6M' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2014-10-10 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.97625 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'DIAMOND BEAMLINE I03' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.97625 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline I03 _diffrn_source.pdbx_synchrotron_site Diamond # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5J68 _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 5.22 _reflns.d_resolution_low 85.802 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 6915 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 100 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 23.8 _reflns.pdbx_Rmerge_I_obs 0.12 _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 17.3 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _reflns_shell.d_res_high 5.22 _reflns_shell.d_res_low ? _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_obs ? _reflns_shell.percent_possible_all ? _reflns_shell.percent_possible_obs ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_obs 3.047 _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_gt ? _reflns_shell.number_unique_gt ? _reflns_shell.percent_possible_gt ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.pdbx_redundancy ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_CC_half ? _reflns_shell.pdbx_R_split ? # _refine.aniso_B[1][1] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][2] ? _refine.aniso_B[2][3] ? _refine.aniso_B[3][3] ? _refine.B_iso_max ? _refine.B_iso_mean ? _refine.B_iso_min ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.details ? _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 5J68 _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 5.221 _refine.ls_d_res_low 85.802 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 6866 _refine.ls_number_reflns_R_free 359 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 99.88 _refine.ls_percent_reflns_R_free 5.23 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.3483 _refine.ls_R_factor_R_free 0.3645 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.3476 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details ? _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.35 _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_starting_model 5J67 _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error 50.10 _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B ? _refine.overall_SU_ML 1.12 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 4610 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 0 _refine_hist.number_atoms_solvent 0 _refine_hist.number_atoms_total 4610 _refine_hist.d_res_high 5.221 _refine_hist.d_res_low 85.802 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.criterion _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.rejects _refine_ls_restr.type _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' ? 0.005 ? 4725 ? f_bond_d ? ? 'X-RAY DIFFRACTION' ? 0.841 ? 6431 ? f_angle_d ? ? 'X-RAY DIFFRACTION' ? 17.159 ? 2873 ? f_dihedral_angle_d ? ? 'X-RAY DIFFRACTION' ? 0.044 ? 749 ? f_chiral_restr ? ? 'X-RAY DIFFRACTION' ? 0.005 ? 795 ? f_plane_restr ? ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.R_factor_all _refine_ls_shell.R_factor_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.R_factor_R_work _refine_ls_shell.redundancy_reflns_all _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.wR_factor_all _refine_ls_shell.wR_factor_obs _refine_ls_shell.wR_factor_R_free _refine_ls_shell.wR_factor_R_work _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.pdbx_phase_error _refine_ls_shell.pdbx_fsc_work _refine_ls_shell.pdbx_fsc_free 'X-RAY DIFFRACTION' 5.2206 5.9758 . . 131 2082 100.00 . . . 0.4615 . 0.4083 . . . . . . . . . . 'X-RAY DIFFRACTION' 5.9758 7.5282 . . 118 2135 100.00 . . . 0.3994 . 0.3984 . . . . . . . . . . 'X-RAY DIFFRACTION' 7.5282 85.8133 . . 110 2290 100.00 . . . 0.3413 . 0.3310 . . . . . . . . . . # _struct.entry_id 5J68 _struct.title 'Structure of Astrotactin-2, a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development' _struct.pdbx_descriptor Astrotactin-2 _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5J68 _struct_keywords.text 'MACPF, annexin-like, fibronectin, neural guidance, membrane protein' _struct_keywords.pdbx_keywords 'MEMBRANE PROTEIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 3 ? E N N 4 ? F N N 4 ? G N N 4 ? H N N 4 ? I N N 4 ? J N N 4 ? K N N 4 ? L N N 2 ? M N N 5 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 LEU A 69 ? THR A 73 ? LEU A 785 THR A 789 5 ? 5 HELX_P HELX_P2 AA2 ALA A 107 ? THR A 118 ? ALA A 823 THR A 834 1 ? 12 HELX_P HELX_P3 AA3 SER A 122 ? GLY A 134 ? SER A 838 GLY A 850 1 ? 13 HELX_P HELX_P4 AA4 SER A 155 ? THR A 171 ? SER A 871 THR A 887 1 ? 17 HELX_P HELX_P5 AA5 PRO A 183 ? ALA A 194 ? PRO A 899 ALA A 910 1 ? 12 HELX_P HELX_P6 AA6 GLN A 195 ? LEU A 197 ? GLN A 911 LEU A 913 5 ? 3 HELX_P HELX_P7 AA7 TYR A 247 ? ILE A 250 ? TYR A 963 ILE A 966 5 ? 4 HELX_P HELX_P8 AA8 ASP A 252 ? CYS A 269 ? ASP A 968 CYS A 985 1 ? 18 HELX_P HELX_P9 AA9 ASP A 427 ? TYR A 445 ? ASP A 1143 TYR A 1161 1 ? 19 HELX_P HELX_P10 AB1 SER A 447 ? VAL A 461 ? SER A 1163 VAL A 1177 1 ? 15 HELX_P HELX_P11 AB2 SER A 462 ? GLU A 478 ? SER A 1178 GLU A 1194 1 ? 17 HELX_P HELX_P12 AB3 LYS A 479 ? GLY A 481 ? LYS A 1195 GLY A 1197 5 ? 3 HELX_P HELX_P13 AB4 ASP A 482 ? GLY A 492 ? ASP A 1198 GLY A 1208 1 ? 11 HELX_P HELX_P14 AB5 GLY A 492 ? ARG A 505 ? GLY A 1208 ARG A 1221 1 ? 14 HELX_P HELX_P15 AB6 SER A 507 ? LEU A 514 ? SER A 1223 LEU A 1230 1 ? 8 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 58 SG ? ? ? 1_555 A CYS 220 SG ? ? A CYS 774 A CYS 936 1_555 ? ? ? ? ? ? ? 2.033 ? disulf2 disulf ? ? A CYS 149 SG ? ? ? 1_555 A CYS 210 SG ? ? A CYS 865 A CYS 926 1_555 ? ? ? ? ? ? ? 2.031 ? disulf3 disulf ? ? A CYS 216 SG ? ? ? 1_555 A CYS 223 SG ? ? A CYS 932 A CYS 939 1_555 ? ? ? ? ? ? ? 2.035 ? disulf4 disulf ? ? A CYS 269 SG ? ? ? 1_555 A CYS 280 SG ? ? A CYS 985 A CYS 996 1_555 ? ? ? ? ? ? ? 2.034 ? disulf5 disulf ? ? A CYS 282 SG ? ? ? 1_555 A CYS 295 SG ? ? A CYS 998 A CYS 1011 1_555 ? ? ? ? ? ? ? 2.031 ? disulf6 disulf ? ? A CYS 369 SG ? ? ? 1_555 A CYS 391 SG ? ? A CYS 1085 A CYS 1107 1_555 ? ? ? ? ? ? ? 2.032 ? disulf7 disulf ? ? A CYS 423 SG ? ? ? 1_555 A CYS 510 SG ? ? A CYS 1139 A CYS 1226 1_555 ? ? ? ? ? ? ? 2.031 ? disulf8 disulf ? ? A CYS 531 SG ? ? ? 1_555 A CYS 554 SG ? ? A CYS 1247 A CYS 1270 1_555 ? ? ? ? ? ? ? 2.032 ? covale1 covale one ? A ASN 3 ND2 ? ? ? 1_555 L NAG . C1 ? ? A ASN 719 A NAG 1310 1_555 ? ? ? ? ? ? ? 1.437 ? covale2 covale one ? A ASN 16 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 732 A NAG 1300 1_555 ? ? ? ? ? ? ? 1.446 ? covale3 covale both ? B NAG . O4 ? ? ? 1_555 C NAG . C1 ? ? A NAG 1300 A NAG 1301 1_555 ? ? ? ? ? ? ? 1.439 ? covale4 covale both ? C NAG . O4 ? ? ? 1_555 D BMA . C1 ? ? A NAG 1301 A BMA 1302 1_555 ? ? ? ? ? ? ? 1.446 ? covale5 covale one ? D BMA . O3 ? ? ? 1_555 J MAN . C1 ? ? A BMA 1302 A MAN 1308 1_555 ? ? ? ? ? ? ? 1.442 ? covale6 covale one ? D BMA . O6 ? ? ? 1_555 E MAN . C1 ? ? A BMA 1302 A MAN 1303 1_555 ? ? ? ? ? ? ? 1.443 ? covale7 covale one ? E MAN . O3 ? ? ? 1_555 F MAN . C1 ? ? A MAN 1303 A MAN 1304 1_555 ? ? ? ? ? ? ? 1.438 ? covale8 covale one ? E MAN . O6 ? ? ? 1_555 H MAN . C1 ? ? A MAN 1303 A MAN 1306 1_555 ? ? ? ? ? ? ? 1.442 ? covale9 covale one ? F MAN . O2 ? ? ? 1_555 G MAN . C1 ? ? A MAN 1304 A MAN 1305 1_555 ? ? ? ? ? ? ? 1.454 ? covale10 covale one ? H MAN . O2 ? ? ? 1_555 I MAN . C1 ? ? A MAN 1306 A MAN 1307 1_555 ? ? ? ? ? ? ? 1.440 ? covale11 covale one ? J MAN . O2 ? ? ? 1_555 K MAN . C1 ? ? A MAN 1308 A MAN 1309 1_555 ? ? ? ? ? ? ? 1.443 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 7 A . ? PHE 723 A GLY 8 A ? GLY 724 A 1 16.13 2 SER 102 A . ? SER 818 A THR 103 A ? THR 819 A 1 -2.26 3 LEU 284 A . ? LEU 1000 A SER 285 A ? SER 1001 A 1 1.51 4 LEU 365 A . ? LEU 1081 A GLY 366 A ? GLY 1082 A 1 -0.82 5 THR 367 A . ? THR 1083 A SER 368 A ? SER 1084 A 1 4.12 6 PRO 380 A . ? PRO 1096 A GLU 381 A ? GLU 1097 A 1 6.72 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 4 ? AA2 ? 3 ? AA3 ? 4 ? AA4 ? 2 ? AA5 ? 4 ? AA6 ? 4 ? AA7 ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? anti-parallel AA1 3 4 ? anti-parallel AA2 1 2 ? anti-parallel AA2 2 3 ? anti-parallel AA3 1 2 ? anti-parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA4 1 2 ? anti-parallel AA5 1 2 ? anti-parallel AA5 2 3 ? anti-parallel AA5 3 4 ? anti-parallel AA6 1 2 ? anti-parallel AA6 2 3 ? anti-parallel AA6 3 4 ? anti-parallel AA7 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 LEU A 47 ? PRO A 51 ? LEU A 763 PRO A 767 AA1 2 TYR A 97 ? LEU A 101 ? TYR A 813 LEU A 817 AA1 3 HIS A 136 ? GLY A 144 ? HIS A 852 GLY A 860 AA1 4 VAL A 236 ? PRO A 245 ? VAL A 952 PRO A 961 AA2 1 ARG A 59 ? LEU A 62 ? ARG A 775 LEU A 778 AA2 2 MET A 86 ? ARG A 93 ? MET A 802 ARG A 809 AA2 3 LEU A 66 ? PRO A 67 ? LEU A 782 PRO A 783 AA3 1 ARG A 59 ? LEU A 62 ? ARG A 775 LEU A 778 AA3 2 MET A 86 ? ARG A 93 ? MET A 802 ARG A 809 AA3 3 GLU A 146 ? PHE A 153 ? GLU A 862 PHE A 869 AA3 4 GLU A 207 ? LYS A 213 ? GLU A 923 LYS A 929 AA4 1 GLY A 273 ? ILE A 276 ? GLY A 989 ILE A 992 AA4 2 TRP A 279 ? CYS A 282 ? TRP A 995 CYS A 998 AA5 1 ARG A 304 ? LEU A 305 ? ARG A 1020 LEU A 1021 AA5 2 VAL A 316 ? VAL A 321 ? VAL A 1032 VAL A 1037 AA5 3 SER A 383 ? PHE A 389 ? SER A 1099 PHE A 1105 AA5 4 VAL A 370 ? HIS A 376 ? VAL A 1086 HIS A 1092 AA6 1 GLU A 353 ? SER A 356 ? GLU A 1069 SER A 1072 AA6 2 VAL A 331 ? VAL A 341 ? VAL A 1047 VAL A 1057 AA6 3 LEU A 397 ? ASP A 406 ? LEU A 1113 ASP A 1122 AA6 4 SER A 415 ? ARG A 420 ? SER A 1131 ARG A 1136 AA7 1 TYR A 518 ? SER A 533 ? TYR A 1234 SER A 1249 AA7 2 ILE A 552 ? GLY A 567 ? ILE A 1268 GLY A 1283 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N LEU A 48 ? N LEU A 764 O LYS A 100 ? O LYS A 816 AA1 2 3 N VAL A 99 ? N VAL A 815 O ALA A 141 ? O ALA A 857 AA1 3 4 N LEU A 142 ? N LEU A 858 O LEU A 238 ? O LEU A 954 AA2 1 2 N VAL A 61 ? N VAL A 777 O ARG A 91 ? O ARG A 807 AA2 2 3 O VAL A 87 ? O VAL A 803 N LEU A 66 ? N LEU A 782 AA3 1 2 N VAL A 61 ? N VAL A 777 O ARG A 91 ? O ARG A 807 AA3 2 3 N TRP A 90 ? N TRP A 806 O CYS A 149 ? O CYS A 865 AA3 3 4 N HIS A 152 ? N HIS A 868 O GLU A 207 ? O GLU A 923 AA4 1 2 N ASP A 274 ? N ASP A 990 O ARG A 281 ? O ARG A 997 AA5 1 2 N ARG A 304 ? N ARG A 1020 O GLU A 319 ? O GLU A 1035 AA5 2 3 N VAL A 316 ? N VAL A 1032 O PHE A 389 ? O PHE A 1105 AA5 3 4 O ILE A 384 ? O ILE A 1100 N SER A 375 ? N SER A 1091 AA6 1 2 O LEU A 355 ? O LEU A 1071 N LEU A 336 ? N LEU A 1052 AA6 2 3 N ILE A 335 ? N ILE A 1051 O TYR A 403 ? O TYR A 1119 AA6 3 4 N PHE A 400 ? N PHE A 1116 O VAL A 417 ? O VAL A 1133 AA7 1 2 N GLU A 524 ? N GLU A 1240 O MET A 561 ? O MET A 1277 # _atom_sites.entry_id 5J68 _atom_sites.fract_transf_matrix[1][1] 0.009625 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009625 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.003286 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O P S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . LYS A 1 1 ? 4.805 43.460 -13.778 1.00 363.76 ? 717 LYS A N 1 ATOM 2 C CA . LYS A 1 1 ? 5.300 42.339 -14.578 1.00 363.31 ? 717 LYS A CA 1 ATOM 3 C C . LYS A 1 1 ? 4.368 41.138 -14.486 1.00 358.06 ? 717 LYS A C 1 ATOM 4 O O . LYS A 1 1 ? 3.463 41.103 -13.656 1.00 354.74 ? 717 LYS A O 1 ATOM 5 C CB . LYS A 1 1 ? 6.710 41.948 -14.134 1.00 366.78 ? 717 LYS A CB 1 ATOM 6 C CG . LYS A 1 1 ? 7.741 43.048 -14.304 1.00 369.95 ? 717 LYS A CG 1 ATOM 7 C CD . LYS A 1 1 ? 9.101 42.600 -13.803 1.00 372.63 ? 717 LYS A CD 1 ATOM 8 C CE . LYS A 1 1 ? 10.127 43.714 -13.916 1.00 374.40 ? 717 LYS A CE 1 ATOM 9 N NZ . LYS A 1 1 ? 11.446 43.311 -13.356 1.00 376.05 ? 717 LYS A NZ 1 ATOM 10 N N . PHE A 1 2 ? 4.601 40.151 -15.346 1.00 384.50 ? 718 PHE A N 1 ATOM 11 C CA . PHE A 1 2 ? 3.749 38.970 -15.434 1.00 380.38 ? 718 PHE A CA 1 ATOM 12 C C . PHE A 1 2 ? 4.336 37.865 -14.563 1.00 377.01 ? 718 PHE A C 1 ATOM 13 O O . PHE A 1 2 ? 5.425 37.352 -14.846 1.00 373.31 ? 718 PHE A O 1 ATOM 14 C CB . PHE A 1 2 ? 3.615 38.526 -16.894 1.00 377.49 ? 718 PHE A CB 1 ATOM 15 C CG . PHE A 1 2 ? 2.920 37.206 -17.071 1.00 373.37 ? 718 PHE A CG 1 ATOM 16 C CD1 . PHE A 1 2 ? 1.628 37.016 -16.614 1.00 370.85 ? 718 PHE A CD1 1 ATOM 17 C CD2 . PHE A 1 2 ? 3.558 36.158 -17.718 1.00 371.87 ? 718 PHE A CD2 1 ATOM 18 C CE1 . PHE A 1 2 ? 0.987 35.801 -16.784 1.00 369.52 ? 718 PHE A CE1 1 ATOM 19 C CE2 . PHE A 1 2 ? 2.921 34.942 -17.893 1.00 371.94 ? 718 PHE A CE2 1 ATOM 20 C CZ . PHE A 1 2 ? 1.636 34.763 -17.424 1.00 371.20 ? 718 PHE A CZ 1 ATOM 21 N N . ASN A 1 3 ? 3.624 37.512 -13.494 1.00 365.97 ? 719 ASN A N 1 ATOM 22 C CA . ASN A 1 3 ? 4.028 36.413 -12.622 1.00 363.44 ? 719 ASN A CA 1 ATOM 23 C C . ASN A 1 3 ? 3.681 35.095 -13.304 1.00 359.36 ? 719 ASN A C 1 ATOM 24 O O . ASN A 1 3 ? 2.501 34.760 -13.451 1.00 357.37 ? 719 ASN A O 1 ATOM 25 C CB . ASN A 1 3 ? 3.322 36.497 -11.270 1.00 363.91 ? 719 ASN A CB 1 ATOM 26 C CG . ASN A 1 3 ? 3.648 37.761 -10.496 1.00 364.05 ? 719 ASN A CG 1 ATOM 27 O OD1 . ASN A 1 3 ? 4.674 38.409 -10.706 1.00 362.93 ? 719 ASN A OD1 1 ATOM 28 N ND2 . ASN A 1 3 ? 2.752 38.106 -9.574 1.00 365.79 ? 719 ASN A ND2 1 ATOM 29 N N . ASP A 1 4 ? 4.695 34.337 -13.710 1.00 372.00 ? 720 ASP A N 1 ATOM 30 C CA . ASP A 1 4 ? 4.482 33.050 -14.358 1.00 369.14 ? 720 ASP A CA 1 ATOM 31 C C . ASP A 1 4 ? 5.188 31.951 -13.577 1.00 364.03 ? 720 ASP A C 1 ATOM 32 O O . ASP A 1 4 ? 6.332 32.115 -13.139 1.00 365.06 ? 720 ASP A O 1 ATOM 33 C CB . ASP A 1 4 ? 4.960 33.074 -15.822 1.00 370.94 ? 720 ASP A CB 1 ATOM 34 C CG . ASP A 1 4 ? 6.251 32.309 -16.038 1.00 369.24 ? 720 ASP A CG 1 ATOM 35 O OD1 . ASP A 1 4 ? 7.331 32.877 -15.771 1.00 372.31 ? 720 ASP A OD1 1 ATOM 36 O OD2 . ASP A 1 4 ? 6.189 31.144 -16.485 1.00 370.21 ? 720 ASP A OD2 1 ATOM 37 N N . THR A 1 5 ? 4.482 30.838 -13.385 1.00 361.99 ? 721 THR A N 1 ATOM 38 C CA . THR A 1 5 ? 5.018 29.662 -12.716 1.00 360.07 ? 721 THR A CA 1 ATOM 39 C C . THR A 1 5 ? 4.416 28.427 -13.370 1.00 359.77 ? 721 THR A C 1 ATOM 40 O O . THR A 1 5 ? 3.635 28.521 -14.322 1.00 363.67 ? 721 THR A O 1 ATOM 41 C CB . THR A 1 5 ? 4.724 29.686 -11.210 1.00 358.56 ? 721 THR A CB 1 ATOM 42 O OG1 . THR A 1 5 ? 5.253 28.502 -10.598 1.00 360.59 ? 721 THR A OG1 1 ATOM 43 C CG2 . THR A 1 5 ? 3.224 29.754 -10.956 1.00 358.19 ? 721 THR A CG2 1 ATOM 44 N N . LEU A 1 6 ? 4.785 27.258 -12.853 1.00 358.78 ? 722 LEU A N 1 ATOM 45 C CA . LEU A 1 6 ? 4.231 26.007 -13.350 1.00 356.58 ? 722 LEU A CA 1 ATOM 46 C C . LEU A 1 6 ? 2.925 25.689 -12.632 1.00 358.77 ? 722 LEU A C 1 ATOM 47 O O . LEU A 1 6 ? 2.819 25.827 -11.411 1.00 365.48 ? 722 LEU A O 1 ATOM 48 C CB . LEU A 1 6 ? 5.229 24.865 -13.164 1.00 355.89 ? 722 LEU A CB 1 ATOM 49 C CG . LEU A 1 6 ? 4.951 23.535 -13.872 1.00 357.00 ? 722 LEU A CG 1 ATOM 50 C CD1 . LEU A 1 6 ? 4.839 23.718 -15.379 1.00 359.36 ? 722 LEU A CD1 1 ATOM 51 C CD2 . LEU A 1 6 ? 6.044 22.530 -13.536 1.00 358.61 ? 722 LEU A CD2 1 ATOM 52 N N . PHE A 1 7 ? 1.931 25.260 -13.413 1.00 358.07 ? 723 PHE A N 1 ATOM 53 C CA . PHE A 1 7 ? 0.576 24.973 -12.931 1.00 359.94 ? 723 PHE A CA 1 ATOM 54 C C . PHE A 1 7 ? -0.057 26.134 -12.156 1.00 363.26 ? 723 PHE A C 1 ATOM 55 O O . PHE A 1 7 ? -0.772 25.895 -11.179 1.00 372.48 ? 723 PHE A O 1 ATOM 56 C CB . PHE A 1 7 ? 0.543 23.729 -12.031 1.00 361.51 ? 723 PHE A CB 1 ATOM 57 C CG . PHE A 1 7 ? 1.385 22.583 -12.509 1.00 361.90 ? 723 PHE A CG 1 ATOM 58 C CD1 . PHE A 1 7 ? 1.097 21.934 -13.696 1.00 361.61 ? 723 PHE A CD1 1 ATOM 59 C CD2 . PHE A 1 7 ? 2.434 22.117 -11.733 1.00 364.08 ? 723 PHE A CD2 1 ATOM 60 C CE1 . PHE A 1 7 ? 1.862 20.864 -14.118 1.00 364.19 ? 723 PHE A CE1 1 ATOM 61 C CE2 . PHE A 1 7 ? 3.199 21.046 -12.146 1.00 367.11 ? 723 PHE A CE2 1 ATOM 62 C CZ . PHE A 1 7 ? 2.915 20.420 -13.341 1.00 367.04 ? 723 PHE A CZ 1 ATOM 63 N N . GLY A 1 8 ? 0.106 27.394 -12.573 1.00 355.96 ? 724 GLY A N 1 ATOM 64 C CA . GLY A 1 8 ? 0.559 27.829 -13.881 1.00 357.68 ? 724 GLY A CA 1 ATOM 65 C C . GLY A 1 8 ? -0.488 28.782 -14.415 1.00 361.09 ? 724 GLY A C 1 ATOM 66 O O . GLY A 1 8 ? -0.435 29.992 -14.183 1.00 360.85 ? 724 GLY A O 1 ATOM 67 N N . GLU A 1 9 ? -1.463 28.215 -15.119 1.00 359.82 ? 725 GLU A N 1 ATOM 68 C CA . GLU A 1 9 ? -2.652 28.940 -15.537 1.00 358.73 ? 725 GLU A CA 1 ATOM 69 C C . GLU A 1 9 ? -3.779 28.848 -14.517 1.00 356.80 ? 725 GLU A C 1 ATOM 70 O O . GLU A 1 9 ? -4.819 29.489 -14.703 1.00 361.17 ? 725 GLU A O 1 ATOM 71 C CB . GLU A 1 9 ? -3.142 28.411 -16.890 1.00 357.66 ? 725 GLU A CB 1 ATOM 72 C CG . GLU A 1 9 ? -2.096 28.437 -18.003 1.00 357.85 ? 725 GLU A CG 1 ATOM 73 C CD . GLU A 1 9 ? -1.184 27.220 -17.999 1.00 355.49 ? 725 GLU A CD 1 ATOM 74 O OE1 . GLU A 1 9 ? -1.050 26.569 -16.941 1.00 351.29 ? 725 GLU A OE1 1 ATOM 75 O OE2 . GLU A 1 9 ? -0.601 26.912 -19.060 1.00 355.54 ? 725 GLU A OE2 1 ATOM 76 N N . MET A 1 10 ? -3.592 28.071 -13.445 1.00 348.05 ? 726 MET A N 1 ATOM 77 C CA . MET A 1 10 ? -4.652 27.869 -12.464 1.00 349.04 ? 726 MET A CA 1 ATOM 78 C C . MET A 1 10 ? -4.905 29.119 -11.631 1.00 348.97 ? 726 MET A C 1 ATOM 79 O O . MET A 1 10 ? -6.025 29.324 -11.149 1.00 346.07 ? 726 MET A O 1 ATOM 80 C CB . MET A 1 10 ? -4.296 26.697 -11.547 1.00 349.26 ? 726 MET A CB 1 ATOM 81 C CG . MET A 1 10 ? -3.991 25.395 -12.273 1.00 351.26 ? 726 MET A CG 1 ATOM 82 S SD . MET A 1 10 ? -5.468 24.544 -12.859 1.00 353.39 ? 726 MET A SD 1 ATOM 83 C CE . MET A 1 10 ? -6.259 24.123 -11.307 1.00 352.93 ? 726 MET A CE 1 ATOM 84 N N . LEU A 1 11 ? -3.890 29.959 -11.451 1.00 353.28 ? 727 LEU A N 1 ATOM 85 C CA . LEU A 1 11 ? -3.968 31.103 -10.555 1.00 355.18 ? 727 LEU A CA 1 ATOM 86 C C . LEU A 1 11 ? -4.368 32.395 -11.255 1.00 355.35 ? 727 LEU A C 1 ATOM 87 O O . LEU A 1 11 ? -4.460 33.434 -10.594 1.00 351.70 ? 727 LEU A O 1 ATOM 88 C CB . LEU A 1 11 ? -2.620 31.312 -9.855 1.00 357.98 ? 727 LEU A CB 1 ATOM 89 C CG . LEU A 1 11 ? -1.968 30.082 -9.221 1.00 356.55 ? 727 LEU A CG 1 ATOM 90 C CD1 . LEU A 1 11 ? -0.597 30.422 -8.662 1.00 354.70 ? 727 LEU A CD1 1 ATOM 91 C CD2 . LEU A 1 11 ? -2.859 29.518 -8.135 1.00 355.53 ? 727 LEU A CD2 1 ATOM 92 N N . HIS A 1 12 ? -4.609 32.365 -12.564 1.00 341.67 ? 728 HIS A N 1 ATOM 93 C CA . HIS A 1 12 ? -4.735 33.597 -13.329 1.00 343.67 ? 728 HIS A CA 1 ATOM 94 C C . HIS A 1 12 ? -6.147 33.908 -13.801 1.00 339.92 ? 728 HIS A C 1 ATOM 95 O O . HIS A 1 12 ? -6.501 35.082 -13.891 1.00 341.92 ? 728 HIS A O 1 ATOM 96 C CB . HIS A 1 12 ? -3.792 33.562 -14.537 1.00 345.27 ? 728 HIS A CB 1 ATOM 97 C CG . HIS A 1 12 ? -2.374 33.898 -14.192 1.00 345.96 ? 728 HIS A CG 1 ATOM 98 N ND1 . HIS A 1 12 ? -1.576 33.071 -13.431 1.00 348.75 ? 728 HIS A ND1 1 ATOM 99 C CD2 . HIS A 1 12 ? -1.618 34.983 -14.486 1.00 347.46 ? 728 HIS A CD2 1 ATOM 100 C CE1 . HIS A 1 12 ? -0.386 33.626 -13.281 1.00 354.98 ? 728 HIS A CE1 1 ATOM 101 N NE2 . HIS A 1 12 ? -0.386 34.787 -13.911 1.00 353.36 ? 728 HIS A NE2 1 ATOM 102 N N . GLY A 1 13 ? -6.958 32.909 -14.089 1.00 333.36 ? 729 GLY A N 1 ATOM 103 C CA . GLY A 1 13 ? -8.301 33.236 -14.522 1.00 335.34 ? 729 GLY A CA 1 ATOM 104 C C . GLY A 1 13 ? -8.515 32.933 -15.991 1.00 337.37 ? 729 GLY A C 1 ATOM 105 O O . GLY A 1 13 ? -7.604 33.052 -16.818 1.00 334.76 ? 729 GLY A O 1 ATOM 106 N N . TYR A 1 14 ? -9.747 32.560 -16.326 1.00 332.59 ? 730 TYR A N 1 ATOM 107 C CA . TYR A 1 14 ? -10.068 31.964 -17.614 1.00 329.58 ? 730 TYR A CA 1 ATOM 108 C C . TYR A 1 14 ? -11.341 32.575 -18.182 1.00 331.44 ? 730 TYR A C 1 ATOM 109 O O . TYR A 1 14 ? -12.310 32.804 -17.453 1.00 333.83 ? 730 TYR A O 1 ATOM 110 C CB . TYR A 1 14 ? -10.220 30.444 -17.454 1.00 328.12 ? 730 TYR A CB 1 ATOM 111 C CG . TYR A 1 14 ? -10.616 29.682 -18.698 1.00 328.89 ? 730 TYR A CG 1 ATOM 112 C CD1 . TYR A 1 14 ? -9.789 29.649 -19.814 1.00 328.39 ? 730 TYR A CD1 1 ATOM 113 C CD2 . TYR A 1 14 ? -11.801 28.959 -18.739 1.00 329.70 ? 730 TYR A CD2 1 ATOM 114 C CE1 . TYR A 1 14 ? -10.147 28.937 -20.944 1.00 331.11 ? 730 TYR A CE1 1 ATOM 115 C CE2 . TYR A 1 14 ? -12.166 28.244 -19.860 1.00 330.47 ? 730 TYR A CE2 1 ATOM 116 C CZ . TYR A 1 14 ? -11.336 28.237 -20.959 1.00 332.79 ? 730 TYR A CZ 1 ATOM 117 O OH . TYR A 1 14 ? -11.701 27.523 -22.073 1.00 334.20 ? 730 TYR A OH 1 ATOM 118 N N . ASN A 1 15 ? -11.329 32.834 -19.487 1.00 325.60 ? 731 ASN A N 1 ATOM 119 C CA . ASN A 1 15 ? -12.484 33.362 -20.205 1.00 326.85 ? 731 ASN A CA 1 ATOM 120 C C . ASN A 1 15 ? -13.190 32.218 -20.924 1.00 324.66 ? 731 ASN A C 1 ATOM 121 O O . ASN A 1 15 ? -12.542 31.403 -21.589 1.00 322.15 ? 731 ASN A O 1 ATOM 122 C CB . ASN A 1 15 ? -12.056 34.442 -21.202 1.00 329.39 ? 731 ASN A CB 1 ATOM 123 C CG . ASN A 1 15 ? -13.236 35.198 -21.806 1.00 332.30 ? 731 ASN A CG 1 ATOM 124 O OD1 . ASN A 1 15 ? -14.330 34.657 -21.962 1.00 330.89 ? 731 ASN A OD1 1 ATOM 125 N ND2 . ASN A 1 15 ? -13.006 36.459 -22.158 1.00 335.27 ? 731 ASN A ND2 1 ATOM 126 N N . ASN A 1 16 ? -14.517 32.163 -20.791 1.00 333.11 ? 732 ASN A N 1 ATOM 127 C CA . ASN A 1 16 ? -15.284 31.101 -21.436 1.00 329.93 ? 732 ASN A CA 1 ATOM 128 C C . ASN A 1 16 ? -15.461 31.356 -22.926 1.00 328.23 ? 732 ASN A C 1 ATOM 129 O O . ASN A 1 16 ? -15.307 30.438 -23.739 1.00 322.03 ? 732 ASN A O 1 ATOM 130 C CB . ASN A 1 16 ? -16.653 30.944 -20.764 1.00 330.09 ? 732 ASN A CB 1 ATOM 131 C CG . ASN A 1 16 ? -16.804 29.605 -20.063 1.00 335.66 ? 732 ASN A CG 1 ATOM 132 O OD1 . ASN A 1 16 ? -15.829 29.062 -19.546 1.00 345.35 ? 732 ASN A OD1 1 ATOM 133 N ND2 . ASN A 1 16 ? -18.026 29.061 -20.041 1.00 336.40 ? 732 ASN A ND2 1 ATOM 134 N N . ARG A 1 17 ? -15.789 32.592 -23.300 1.00 330.65 ? 733 ARG A N 1 ATOM 135 C CA . ARG A 1 17 ? -16.100 32.900 -24.692 1.00 332.11 ? 733 ARG A CA 1 ATOM 136 C C . ARG A 1 17 ? -14.862 32.792 -25.574 1.00 329.80 ? 733 ARG A C 1 ATOM 137 O O . ARG A 1 17 ? -14.809 31.967 -26.494 1.00 328.88 ? 733 ARG A O 1 ATOM 138 C CB . ARG A 1 17 ? -16.718 34.297 -24.789 1.00 333.77 ? 733 ARG A CB 1 ATOM 139 C CG . ARG A 1 17 ? -17.305 34.625 -26.148 1.00 331.71 ? 733 ARG A CG 1 ATOM 140 C CD . ARG A 1 17 ? -17.780 36.067 -26.204 1.00 331.52 ? 733 ARG A CD 1 ATOM 141 N NE . ARG A 1 17 ? -16.695 37.004 -25.927 1.00 330.66 ? 733 ARG A NE 1 ATOM 142 C CZ . ARG A 1 17 ? -15.845 37.453 -26.844 1.00 330.29 ? 733 ARG A CZ 1 ATOM 143 N NH1 . ARG A 1 17 ? -15.953 37.048 -28.102 1.00 330.11 ? 733 ARG A NH1 1 ATOM 144 N NH2 . ARG A 1 17 ? -14.886 38.305 -26.506 1.00 332.36 ? 733 ARG A NH2 1 ATOM 145 N N . THR A 1 18 ? -13.850 33.619 -25.307 1.00 320.44 ? 734 THR A N 1 ATOM 146 C CA . THR A 1 18 ? -12.646 33.622 -26.129 1.00 321.72 ? 734 THR A CA 1 ATOM 147 C C . THR A 1 18 ? -11.702 32.470 -25.806 1.00 320.07 ? 734 THR A C 1 ATOM 148 O O . THR A 1 18 ? -10.723 32.274 -26.536 1.00 316.51 ? 734 THR A O 1 ATOM 149 C CB . THR A 1 18 ? -11.901 34.951 -25.980 1.00 322.79 ? 734 THR A CB 1 ATOM 150 O OG1 . THR A 1 18 ? -10.938 35.079 -27.034 1.00 333.14 ? 734 THR A OG1 1 ATOM 151 C CG2 . THR A 1 18 ? -11.183 35.012 -24.646 1.00 320.06 ? 734 THR A CG2 1 ATOM 152 N N . GLN A 1 19 ? -11.965 31.720 -24.733 1.00 314.10 ? 735 GLN A N 1 ATOM 153 C CA . GLN A 1 19 ? -11.248 30.486 -24.415 1.00 312.07 ? 735 GLN A CA 1 ATOM 154 C C . GLN A 1 19 ? -9.772 30.725 -24.099 1.00 313.44 ? 735 GLN A C 1 ATOM 155 O O . GLN A 1 19 ? -8.938 29.840 -24.302 1.00 311.64 ? 735 GLN A O 1 ATOM 156 C CB . GLN A 1 19 ? -11.389 29.466 -25.552 1.00 312.36 ? 735 GLN A CB 1 ATOM 157 C CG . GLN A 1 19 ? -11.797 28.077 -25.108 1.00 316.14 ? 735 GLN A CG 1 ATOM 158 C CD . GLN A 1 19 ? -12.354 27.249 -26.248 1.00 321.84 ? 735 GLN A CD 1 ATOM 159 O OE1 . GLN A 1 19 ? -13.030 27.772 -27.134 1.00 324.50 ? 735 GLN A OE1 1 ATOM 160 N NE2 . GLN A 1 19 ? -12.069 25.952 -26.235 1.00 325.22 ? 735 GLN A NE2 1 ATOM 161 N N . HIS A 1 20 ? -9.437 31.904 -23.582 1.00 324.57 ? 736 HIS A N 1 ATOM 162 C CA . HIS A 1 20 ? -8.057 32.266 -23.274 1.00 322.26 ? 736 HIS A CA 1 ATOM 163 C C . HIS A 1 20 ? -7.765 32.071 -21.792 1.00 322.20 ? 736 HIS A C 1 ATOM 164 O O . HIS A 1 20 ? -8.584 32.415 -20.935 1.00 322.05 ? 736 HIS A O 1 ATOM 165 C CB . HIS A 1 20 ? -7.774 33.718 -23.661 1.00 323.40 ? 736 HIS A CB 1 ATOM 166 C CG . HIS A 1 20 ? -7.682 33.948 -25.136 1.00 326.01 ? 736 HIS A CG 1 ATOM 167 N ND1 . HIS A 1 20 ? -7.919 35.177 -25.711 1.00 326.38 ? 736 HIS A ND1 1 ATOM 168 C CD2 . HIS A 1 20 ? -7.371 33.110 -26.153 1.00 328.20 ? 736 HIS A CD2 1 ATOM 169 C CE1 . HIS A 1 20 ? -7.762 35.086 -27.020 1.00 328.80 ? 736 HIS A CE1 1 ATOM 170 N NE2 . HIS A 1 20 ? -7.429 33.842 -27.314 1.00 330.42 ? 736 HIS A NE2 1 ATOM 171 N N . VAL A 1 21 ? -6.586 31.520 -21.501 1.00 335.59 ? 737 VAL A N 1 ATOM 172 C CA . VAL A 1 21 ? -6.095 31.421 -20.133 1.00 332.44 ? 737 VAL A CA 1 ATOM 173 C C . VAL A 1 21 ? -5.198 32.621 -19.860 1.00 332.18 ? 737 VAL A C 1 ATOM 174 O O . VAL A 1 21 ? -4.974 33.453 -20.748 1.00 331.97 ? 737 VAL A O 1 ATOM 175 C CB . VAL A 1 21 ? -5.343 30.097 -19.895 1.00 329.20 ? 737 VAL A CB 1 ATOM 176 C CG1 . VAL A 1 21 ? -6.240 28.905 -20.217 1.00 326.77 ? 737 VAL A CG1 1 ATOM 177 C CG2 . VAL A 1 21 ? -4.067 30.051 -20.723 1.00 329.38 ? 737 VAL A CG2 1 ATOM 178 N N . ASN A 1 22 ? -4.687 32.720 -18.630 1.00 338.41 ? 738 ASN A N 1 ATOM 179 C CA . ASN A 1 22 ? -3.774 33.793 -18.226 1.00 339.42 ? 738 ASN A CA 1 ATOM 180 C C . ASN A 1 22 ? -4.421 35.171 -18.393 1.00 343.24 ? 738 ASN A C 1 ATOM 181 O O . ASN A 1 22 ? -3.820 36.107 -18.921 1.00 338.86 ? 738 ASN A O 1 ATOM 182 C CB . ASN A 1 22 ? -2.451 33.713 -18.996 1.00 335.79 ? 738 ASN A CB 1 ATOM 183 C CG . ASN A 1 22 ? -1.664 32.453 -18.675 1.00 332.10 ? 738 ASN A CG 1 ATOM 184 O OD1 . ASN A 1 22 ? -1.679 31.970 -17.543 1.00 326.54 ? 738 ASN A OD1 1 ATOM 185 N ND2 . ASN A 1 22 ? -0.975 31.913 -19.675 1.00 333.58 ? 738 ASN A ND2 1 ATOM 186 N N . GLN A 1 23 ? -5.660 35.289 -17.920 1.00 328.39 ? 739 GLN A N 1 ATOM 187 C CA . GLN A 1 23 ? -6.429 36.532 -18.005 1.00 337.07 ? 739 GLN A CA 1 ATOM 188 C C . GLN A 1 23 ? -6.395 37.205 -16.636 1.00 342.19 ? 739 GLN A C 1 ATOM 189 O O . GLN A 1 23 ? -7.221 36.929 -15.767 1.00 351.26 ? 739 GLN A O 1 ATOM 190 C CB . GLN A 1 23 ? -7.857 36.253 -18.463 1.00 334.93 ? 739 GLN A CB 1 ATOM 191 C CG . GLN A 1 23 ? -7.963 35.755 -19.896 1.00 335.09 ? 739 GLN A CG 1 ATOM 192 C CD . GLN A 1 23 ? -7.715 36.851 -20.917 1.00 339.02 ? 739 GLN A CD 1 ATOM 193 O OE1 . GLN A 1 23 ? -8.262 37.949 -20.811 1.00 342.47 ? 739 GLN A OE1 1 ATOM 194 N NE2 . GLN A 1 23 ? -6.884 36.558 -21.911 1.00 340.75 ? 739 GLN A NE2 1 ATOM 195 N N . GLY A 1 24 ? -5.434 38.110 -16.453 1.00 346.60 ? 740 GLY A N 1 ATOM 196 C CA . GLY A 1 24 ? -5.231 38.723 -15.158 1.00 345.56 ? 740 GLY A CA 1 ATOM 197 C C . GLY A 1 24 ? -4.646 37.720 -14.177 1.00 344.37 ? 740 GLY A C 1 ATOM 198 O O . GLY A 1 24 ? -4.175 36.645 -14.544 1.00 352.53 ? 740 GLY A O 1 ATOM 199 N N . GLN A 1 25 ? -4.679 38.097 -12.901 1.00 355.05 ? 741 GLN A N 1 ATOM 200 C CA . GLN A 1 25 ? -4.254 37.212 -11.820 1.00 350.55 ? 741 GLN A CA 1 ATOM 201 C C . GLN A 1 25 ? -5.316 37.233 -10.730 1.00 349.14 ? 741 GLN A C 1 ATOM 202 O O . GLN A 1 25 ? -5.497 38.249 -10.049 1.00 347.66 ? 741 GLN A O 1 ATOM 203 C CB . GLN A 1 25 ? -2.885 37.614 -11.266 1.00 352.65 ? 741 GLN A CB 1 ATOM 204 C CG . GLN A 1 25 ? -2.280 36.565 -10.341 1.00 353.06 ? 741 GLN A CG 1 ATOM 205 C CD . GLN A 1 25 ? -0.865 36.901 -9.909 1.00 350.09 ? 741 GLN A CD 1 ATOM 206 O OE1 . GLN A 1 25 ? -0.143 37.617 -10.603 1.00 349.58 ? 741 GLN A OE1 1 ATOM 207 N NE2 . GLN A 1 25 ? -0.462 36.384 -8.754 1.00 349.50 ? 741 GLN A NE2 1 ATOM 208 N N . VAL A 1 26 ? -6.002 36.107 -10.565 1.00 354.64 ? 742 VAL A N 1 ATOM 209 C CA . VAL A 1 26 ? -7.104 35.987 -9.617 1.00 355.85 ? 742 VAL A CA 1 ATOM 210 C C . VAL A 1 26 ? -6.603 35.660 -8.216 1.00 357.86 ? 742 VAL A C 1 ATOM 211 O O . VAL A 1 26 ? -6.991 36.301 -7.238 1.00 361.64 ? 742 VAL A O 1 ATOM 212 C CB . VAL A 1 26 ? -8.103 34.929 -10.122 1.00 354.08 ? 742 VAL A CB 1 ATOM 213 C CG1 . VAL A 1 26 ? -9.091 34.569 -9.038 1.00 356.58 ? 742 VAL A CG1 1 ATOM 214 C CG2 . VAL A 1 26 ? -8.828 35.426 -11.361 1.00 353.36 ? 742 VAL A CG2 1 ATOM 215 N N . PHE A 1 27 ? -5.746 34.646 -8.089 1.00 353.92 ? 743 PHE A N 1 ATOM 216 C CA . PHE A 1 27 ? -5.215 34.226 -6.802 1.00 353.07 ? 743 PHE A CA 1 ATOM 217 C C . PHE A 1 27 ? -3.736 34.577 -6.703 1.00 353.52 ? 743 PHE A C 1 ATOM 218 O O . PHE A 1 27 ? -3.038 34.686 -7.715 1.00 351.79 ? 743 PHE A O 1 ATOM 219 C CB . PHE A 1 27 ? -5.409 32.720 -6.586 1.00 353.22 ? 743 PHE A CB 1 ATOM 220 C CG . PHE A 1 27 ? -6.829 32.263 -6.761 1.00 352.45 ? 743 PHE A CG 1 ATOM 221 C CD1 . PHE A 1 27 ? -7.808 32.652 -5.864 1.00 352.20 ? 743 PHE A CD1 1 ATOM 222 C CD2 . PHE A 1 27 ? -7.183 31.443 -7.820 1.00 352.78 ? 743 PHE A CD2 1 ATOM 223 C CE1 . PHE A 1 27 ? -9.116 32.238 -6.021 1.00 353.73 ? 743 PHE A CE1 1 ATOM 224 C CE2 . PHE A 1 27 ? -8.491 31.023 -7.982 1.00 351.98 ? 743 PHE A CE2 1 ATOM 225 C CZ . PHE A 1 27 ? -9.458 31.421 -7.080 1.00 353.33 ? 743 PHE A CZ 1 ATOM 226 N N . GLN A 1 28 ? -3.262 34.753 -5.471 1.00 359.39 ? 744 GLN A N 1 ATOM 227 C CA . GLN A 1 28 ? -1.861 35.082 -5.245 1.00 361.26 ? 744 GLN A CA 1 ATOM 228 C C . GLN A 1 28 ? -1.011 33.819 -5.257 1.00 359.56 ? 744 GLN A C 1 ATOM 229 O O . GLN A 1 28 ? -1.446 32.754 -4.809 1.00 358.63 ? 744 GLN A O 1 ATOM 230 C CB . GLN A 1 28 ? -1.685 35.821 -3.915 1.00 362.00 ? 744 GLN A CB 1 ATOM 231 C CG . GLN A 1 28 ? -1.923 34.966 -2.676 1.00 363.75 ? 744 GLN A CG 1 ATOM 232 C CD . GLN A 1 28 ? -1.661 35.716 -1.384 1.00 364.16 ? 744 GLN A CD 1 ATOM 233 O OE1 . GLN A 1 28 ? -1.724 36.945 -1.343 1.00 364.97 ? 744 GLN A OE1 1 ATOM 234 N NE2 . GLN A 1 28 ? -1.363 34.979 -0.320 1.00 365.03 ? 744 GLN A NE2 1 ATOM 235 N N . MET A 1 29 ? 0.203 33.936 -5.789 1.00 366.17 ? 745 MET A N 1 ATOM 236 C CA . MET A 1 29 ? 1.171 32.847 -5.765 1.00 367.58 ? 745 MET A CA 1 ATOM 237 C C . MET A 1 29 ? 2.223 33.150 -4.706 1.00 368.44 ? 745 MET A C 1 ATOM 238 O O . MET A 1 29 ? 2.870 34.203 -4.745 1.00 373.28 ? 745 MET A O 1 ATOM 239 C CB . MET A 1 29 ? 1.817 32.634 -7.136 1.00 370.77 ? 745 MET A CB 1 ATOM 240 C CG . MET A 1 29 ? 2.423 33.871 -7.777 1.00 373.81 ? 745 MET A CG 1 ATOM 241 S SD . MET A 1 29 ? 3.211 33.499 -9.358 1.00 378.11 ? 745 MET A SD 1 ATOM 242 C CE . MET A 1 29 ? 4.637 32.555 -8.827 1.00 377.14 ? 745 MET A CE 1 ATOM 243 N N . THR A 1 30 ? 2.370 32.238 -3.750 1.00 374.75 ? 746 THR A N 1 ATOM 244 C CA . THR A 1 30 ? 3.350 32.355 -2.683 1.00 371.93 ? 746 THR A CA 1 ATOM 245 C C . THR A 1 30 ? 4.141 31.058 -2.599 1.00 373.14 ? 746 THR A C 1 ATOM 246 O O . THR A 1 30 ? 3.832 30.071 -3.273 1.00 370.34 ? 746 THR A O 1 ATOM 247 C CB . THR A 1 30 ? 2.682 32.667 -1.335 1.00 370.51 ? 746 THR A CB 1 ATOM 248 O OG1 . THR A 1 30 ? 1.689 31.673 -1.051 1.00 369.10 ? 746 THR A OG1 1 ATOM 249 C CG2 . THR A 1 30 ? 2.025 34.040 -1.368 1.00 370.31 ? 746 THR A CG2 1 ATOM 250 N N . PHE A 1 31 ? 5.176 31.065 -1.764 1.00 365.80 ? 747 PHE A N 1 ATOM 251 C CA . PHE A 1 31 ? 6.045 29.904 -1.616 1.00 365.46 ? 747 PHE A CA 1 ATOM 252 C C . PHE A 1 31 ? 6.419 29.700 -0.156 1.00 367.15 ? 747 PHE A C 1 ATOM 253 O O . PHE A 1 31 ? 7.580 29.440 0.179 1.00 370.14 ? 747 PHE A O 1 ATOM 254 C CB . PHE A 1 31 ? 7.292 30.038 -2.489 1.00 365.47 ? 747 PHE A CB 1 ATOM 255 C CG . PHE A 1 31 ? 6.989 30.150 -3.957 1.00 366.96 ? 747 PHE A CG 1 ATOM 256 C CD1 . PHE A 1 31 ? 6.785 29.015 -4.724 1.00 365.67 ? 747 PHE A CD1 1 ATOM 257 C CD2 . PHE A 1 31 ? 6.898 31.390 -4.567 1.00 367.90 ? 747 PHE A CD2 1 ATOM 258 C CE1 . PHE A 1 31 ? 6.501 29.114 -6.074 1.00 364.08 ? 747 PHE A CE1 1 ATOM 259 C CE2 . PHE A 1 31 ? 6.615 31.497 -5.916 1.00 367.19 ? 747 PHE A CE2 1 ATOM 260 C CZ . PHE A 1 31 ? 6.417 30.357 -6.670 1.00 365.67 ? 747 PHE A CZ 1 ATOM 261 N N . ARG A 1 32 ? 5.435 29.816 0.737 1.00 366.44 ? 748 ARG A N 1 ATOM 262 C CA . ARG A 1 32 ? 5.675 29.535 2.149 1.00 370.00 ? 748 ARG A CA 1 ATOM 263 C C . ARG A 1 32 ? 5.584 28.040 2.432 1.00 367.84 ? 748 ARG A C 1 ATOM 264 O O . ARG A 1 32 ? 6.509 27.454 3.007 1.00 374.96 ? 748 ARG A O 1 ATOM 265 C CB . ARG A 1 32 ? 4.692 30.324 3.017 1.00 372.22 ? 748 ARG A CB 1 ATOM 266 C CG . ARG A 1 32 ? 4.980 31.818 3.030 1.00 373.90 ? 748 ARG A CG 1 ATOM 267 C CD . ARG A 1 32 ? 4.088 32.566 4.006 1.00 376.19 ? 748 ARG A CD 1 ATOM 268 N NE . ARG A 1 32 ? 2.769 32.855 3.451 1.00 378.98 ? 748 ARG A NE 1 ATOM 269 C CZ . ARG A 1 32 ? 2.503 33.891 2.662 1.00 380.54 ? 748 ARG A CZ 1 ATOM 270 N NH1 . ARG A 1 32 ? 1.273 34.084 2.204 1.00 380.85 ? 748 ARG A NH1 1 ATOM 271 N NH2 . ARG A 1 32 ? 3.470 34.734 2.324 1.00 380.14 ? 748 ARG A NH2 1 ATOM 272 N N . GLU A 1 33 ? 4.486 27.406 2.033 1.00 355.54 ? 749 GLU A N 1 ATOM 273 C CA . GLU A 1 33 ? 4.431 25.952 2.040 1.00 355.25 ? 749 GLU A CA 1 ATOM 274 C C . GLU A 1 33 ? 5.378 25.401 0.980 1.00 353.32 ? 749 GLU A C 1 ATOM 275 O O . GLU A 1 33 ? 5.622 26.034 -0.052 1.00 362.20 ? 749 GLU A O 1 ATOM 276 C CB . GLU A 1 33 ? 3.004 25.464 1.790 1.00 359.30 ? 749 GLU A CB 1 ATOM 277 C CG . GLU A 1 33 ? 1.999 25.946 2.826 1.00 363.24 ? 749 GLU A CG 1 ATOM 278 C CD . GLU A 1 33 ? 0.587 25.475 2.538 1.00 366.80 ? 749 GLU A CD 1 ATOM 279 O OE1 . GLU A 1 33 ? -0.053 24.913 3.452 1.00 368.90 ? 749 GLU A OE1 1 ATOM 280 O OE2 . GLU A 1 33 ? 0.120 25.662 1.395 1.00 367.79 ? 749 GLU A OE2 1 ATOM 281 N N . ASN A 1 34 ? 5.921 24.216 1.243 1.00 356.47 ? 750 ASN A N 1 ATOM 282 C CA . ASN A 1 34 ? 7.003 23.654 0.437 1.00 356.14 ? 750 ASN A CA 1 ATOM 283 C C . ASN A 1 34 ? 6.477 22.476 -0.377 1.00 360.31 ? 750 ASN A C 1 ATOM 284 O O . ASN A 1 34 ? 6.526 21.326 0.060 1.00 364.94 ? 750 ASN A O 1 ATOM 285 C CB . ASN A 1 34 ? 8.167 23.243 1.334 1.00 353.34 ? 750 ASN A CB 1 ATOM 286 C CG . ASN A 1 34 ? 8.721 24.403 2.130 1.00 352.11 ? 750 ASN A CG 1 ATOM 287 O OD1 . ASN A 1 34 ? 8.701 25.546 1.676 1.00 349.20 ? 750 ASN A OD1 1 ATOM 288 N ND2 . ASN A 1 34 ? 9.216 24.116 3.326 1.00 353.64 ? 750 ASN A ND2 1 ATOM 289 N N . ASN A 1 35 ? 5.990 22.773 -1.578 1.00 351.83 ? 751 ASN A N 1 ATOM 290 C CA . ASN A 1 35 ? 5.447 21.766 -2.485 1.00 350.68 ? 751 ASN A CA 1 ATOM 291 C C . ASN A 1 35 ? 6.432 21.511 -3.621 1.00 348.67 ? 751 ASN A C 1 ATOM 292 O O . ASN A 1 35 ? 6.713 22.411 -4.420 1.00 345.85 ? 751 ASN A O 1 ATOM 293 C CB . ASN A 1 35 ? 4.093 22.204 -3.040 1.00 357.66 ? 751 ASN A CB 1 ATOM 294 C CG . ASN A 1 35 ? 2.961 21.996 -2.052 1.00 364.81 ? 751 ASN A CG 1 ATOM 295 O OD1 . ASN A 1 35 ? 2.899 20.973 -1.369 1.00 365.87 ? 751 ASN A OD1 1 ATOM 296 N ND2 . ASN A 1 35 ? 2.057 22.965 -1.975 1.00 371.71 ? 751 ASN A ND2 1 ATOM 297 N N . PHE A 1 36 ? 6.945 20.286 -3.689 1.00 357.51 ? 752 PHE A N 1 ATOM 298 C CA . PHE A 1 36 ? 7.836 19.828 -4.747 1.00 357.90 ? 752 PHE A CA 1 ATOM 299 C C . PHE A 1 36 ? 7.207 18.633 -5.453 1.00 357.04 ? 752 PHE A C 1 ATOM 300 O O . PHE A 1 36 ? 6.205 18.073 -5.002 1.00 354.01 ? 752 PHE A O 1 ATOM 301 C CB . PHE A 1 36 ? 9.212 19.446 -4.182 1.00 360.25 ? 752 PHE A CB 1 ATOM 302 C CG . PHE A 1 36 ? 10.176 20.597 -4.079 1.00 361.24 ? 752 PHE A CG 1 ATOM 303 C CD1 . PHE A 1 36 ? 9.822 21.767 -3.429 1.00 359.13 ? 752 PHE A CD1 1 ATOM 304 C CD2 . PHE A 1 36 ? 11.451 20.493 -4.615 1.00 366.52 ? 752 PHE A CD2 1 ATOM 305 C CE1 . PHE A 1 36 ? 10.714 22.818 -3.331 1.00 360.99 ? 752 PHE A CE1 1 ATOM 306 C CE2 . PHE A 1 36 ? 12.347 21.541 -4.519 1.00 368.85 ? 752 PHE A CE2 1 ATOM 307 C CZ . PHE A 1 36 ? 11.978 22.705 -3.877 1.00 366.30 ? 752 PHE A CZ 1 ATOM 308 N N . ILE A 1 37 ? 7.809 18.236 -6.574 1.00 345.38 ? 753 ILE A N 1 ATOM 309 C CA . ILE A 1 37 ? 7.351 17.063 -7.313 1.00 350.03 ? 753 ILE A CA 1 ATOM 310 C C . ILE A 1 37 ? 8.539 16.152 -7.600 1.00 354.00 ? 753 ILE A C 1 ATOM 311 O O . ILE A 1 37 ? 8.788 15.190 -6.865 1.00 362.06 ? 753 ILE A O 1 ATOM 312 C CB . ILE A 1 37 ? 6.626 17.457 -8.614 1.00 352.25 ? 753 ILE A CB 1 ATOM 313 C CG1 . ILE A 1 37 ? 5.398 18.316 -8.309 1.00 353.04 ? 753 ILE A CG1 1 ATOM 314 C CG2 . ILE A 1 37 ? 6.195 16.216 -9.386 1.00 356.42 ? 753 ILE A CG2 1 ATOM 315 C CD1 . ILE A 1 37 ? 4.297 17.575 -7.578 1.00 354.08 ? 753 ILE A CD1 1 ATOM 316 N N . LYS A 1 38 ? 9.280 16.450 -8.668 1.00 347.75 ? 754 LYS A N 1 ATOM 317 C CA . LYS A 1 38 ? 10.419 15.630 -9.065 1.00 353.43 ? 754 LYS A CA 1 ATOM 318 C C . LYS A 1 38 ? 11.629 16.505 -9.364 1.00 356.17 ? 754 LYS A C 1 ATOM 319 O O . LYS A 1 38 ? 12.387 16.859 -8.456 1.00 362.96 ? 754 LYS A O 1 ATOM 320 C CB . LYS A 1 38 ? 10.071 14.775 -10.287 1.00 358.05 ? 754 LYS A CB 1 ATOM 321 C CG . LYS A 1 38 ? 8.962 13.757 -10.064 1.00 358.34 ? 754 LYS A CG 1 ATOM 322 C CD . LYS A 1 38 ? 8.755 12.901 -11.308 1.00 361.01 ? 754 LYS A CD 1 ATOM 323 C CE . LYS A 1 38 ? 7.642 11.882 -11.113 1.00 361.88 ? 754 LYS A CE 1 ATOM 324 N NZ . LYS A 1 38 ? 6.307 12.528 -10.973 1.00 363.74 ? 754 LYS A NZ 1 ATOM 325 N N . ASP A 1 39 ? 11.820 16.848 -10.637 1.00 369.41 ? 755 ASP A N 1 ATOM 326 C CA . ASP A 1 39 ? 12.863 17.775 -11.051 1.00 372.99 ? 755 ASP A CA 1 ATOM 327 C C . ASP A 1 39 ? 12.348 19.198 -11.223 1.00 365.99 ? 755 ASP A C 1 ATOM 328 O O . ASP A 1 39 ? 13.148 20.107 -11.467 1.00 369.85 ? 755 ASP A O 1 ATOM 329 C CB . ASP A 1 39 ? 13.504 17.304 -12.362 1.00 379.23 ? 755 ASP A CB 1 ATOM 330 C CG . ASP A 1 39 ? 14.299 16.024 -12.196 1.00 382.55 ? 755 ASP A CG 1 ATOM 331 O OD1 . ASP A 1 39 ? 15.177 15.978 -11.309 1.00 384.92 ? 755 ASP A OD1 1 ATOM 332 O OD2 . ASP A 1 39 ? 14.042 15.064 -12.953 1.00 381.79 ? 755 ASP A OD2 1 ATOM 333 N N . PHE A 1 40 ? 11.039 19.405 -11.101 1.00 373.16 ? 756 PHE A N 1 ATOM 334 C CA . PHE A 1 40 ? 10.458 20.725 -11.242 1.00 367.44 ? 756 PHE A CA 1 ATOM 335 C C . PHE A 1 40 ? 10.778 21.578 -10.016 1.00 363.67 ? 756 PHE A C 1 ATOM 336 O O . PHE A 1 40 ? 11.028 21.051 -8.929 1.00 361.19 ? 756 PHE A O 1 ATOM 337 C CB . PHE A 1 40 ? 8.946 20.616 -11.428 1.00 365.68 ? 756 PHE A CB 1 ATOM 338 C CG . PHE A 1 40 ? 8.534 19.611 -12.468 1.00 364.52 ? 756 PHE A CG 1 ATOM 339 C CD1 . PHE A 1 40 ? 9.184 19.549 -13.691 1.00 364.55 ? 756 PHE A CD1 1 ATOM 340 C CD2 . PHE A 1 40 ? 7.505 18.718 -12.217 1.00 362.55 ? 756 PHE A CD2 1 ATOM 341 C CE1 . PHE A 1 40 ? 8.808 18.621 -14.646 1.00 364.74 ? 756 PHE A CE1 1 ATOM 342 C CE2 . PHE A 1 40 ? 7.125 17.789 -13.167 1.00 362.77 ? 756 PHE A CE2 1 ATOM 343 C CZ . PHE A 1 40 ? 7.777 17.740 -14.384 1.00 366.37 ? 756 PHE A CZ 1 ATOM 344 N N . PRO A 1 41 ? 10.784 22.908 -10.168 1.00 361.26 ? 757 PRO A N 1 ATOM 345 C CA . PRO A 1 41 ? 11.054 23.780 -9.016 1.00 359.31 ? 757 PRO A CA 1 ATOM 346 C C . PRO A 1 41 ? 9.951 23.742 -7.970 1.00 357.47 ? 757 PRO A C 1 ATOM 347 O O . PRO A 1 41 ? 9.066 22.880 -8.010 1.00 356.75 ? 757 PRO A O 1 ATOM 348 C CB . PRO A 1 41 ? 11.168 25.175 -9.650 1.00 360.66 ? 757 PRO A CB 1 ATOM 349 C CG . PRO A 1 41 ? 11.470 24.917 -11.093 1.00 361.46 ? 757 PRO A CG 1 ATOM 350 C CD . PRO A 1 41 ? 10.740 23.660 -11.433 1.00 361.98 ? 757 PRO A CD 1 ATOM 351 N N . GLN A 1 42 ? 9.996 24.678 -7.027 1.00 355.03 ? 758 GLN A N 1 ATOM 352 C CA . GLN A 1 42 ? 8.991 24.731 -5.975 1.00 356.57 ? 758 GLN A CA 1 ATOM 353 C C . GLN A 1 42 ? 7.658 25.201 -6.541 1.00 353.38 ? 758 GLN A C 1 ATOM 354 O O . GLN A 1 42 ? 7.591 26.217 -7.238 1.00 355.99 ? 758 GLN A O 1 ATOM 355 C CB . GLN A 1 42 ? 9.451 25.658 -4.851 1.00 359.58 ? 758 GLN A CB 1 ATOM 356 C CG . GLN A 1 42 ? 8.518 25.690 -3.651 1.00 360.82 ? 758 GLN A CG 1 ATOM 357 C CD . GLN A 1 42 ? 9.128 26.397 -2.456 1.00 363.20 ? 758 GLN A CD 1 ATOM 358 O OE1 . GLN A 1 42 ? 10.342 26.586 -2.385 1.00 365.16 ? 758 GLN A OE1 1 ATOM 359 N NE2 . GLN A 1 42 ? 8.285 26.791 -1.508 1.00 366.27 ? 758 GLN A NE2 1 ATOM 360 N N . LEU A 1 43 ? 6.597 24.457 -6.243 1.00 360.41 ? 759 LEU A N 1 ATOM 361 C CA . LEU A 1 43 ? 5.270 24.819 -6.710 1.00 359.49 ? 759 LEU A CA 1 ATOM 362 C C . LEU A 1 43 ? 4.707 25.973 -5.887 1.00 363.79 ? 759 LEU A C 1 ATOM 363 O O . LEU A 1 43 ? 5.122 26.226 -4.752 1.00 371.69 ? 759 LEU A O 1 ATOM 364 C CB . LEU A 1 43 ? 4.322 23.623 -6.629 1.00 357.26 ? 759 LEU A CB 1 ATOM 365 C CG . LEU A 1 43 ? 4.735 22.332 -7.334 1.00 357.08 ? 759 LEU A CG 1 ATOM 366 C CD1 . LEU A 1 43 ? 3.647 21.285 -7.173 1.00 354.95 ? 759 LEU A CD1 1 ATOM 367 C CD2 . LEU A 1 43 ? 5.027 22.587 -8.803 1.00 358.60 ? 759 LEU A CD2 1 ATOM 368 N N . ALA A 1 44 ? 3.746 26.678 -6.478 1.00 374.02 ? 760 ALA A N 1 ATOM 369 C CA . ALA A 1 44 ? 3.010 27.690 -5.740 1.00 372.71 ? 760 ALA A CA 1 ATOM 370 C C . ALA A 1 44 ? 2.133 27.027 -4.681 1.00 373.04 ? 760 ALA A C 1 ATOM 371 O O . ALA A 1 44 ? 1.818 25.836 -4.752 1.00 368.66 ? 760 ALA A O 1 ATOM 372 C CB . ALA A 1 44 ? 2.159 28.537 -6.686 1.00 372.70 ? 760 ALA A CB 1 ATOM 373 N N . ASP A 1 45 ? 1.737 27.815 -3.688 1.00 364.56 ? 761 ASP A N 1 ATOM 374 C CA . ASP A 1 45 ? 1.008 27.278 -2.549 1.00 368.49 ? 761 ASP A CA 1 ATOM 375 C C . ASP A 1 45 ? -0.441 26.978 -2.909 1.00 369.01 ? 761 ASP A C 1 ATOM 376 O O . ASP A 1 45 ? -1.058 27.661 -3.731 1.00 364.28 ? 761 ASP A O 1 ATOM 377 C CB . ASP A 1 45 ? 1.053 28.253 -1.371 1.00 372.35 ? 761 ASP A CB 1 ATOM 378 C CG . ASP A 1 45 ? 2.462 28.492 -0.865 1.00 374.21 ? 761 ASP A CG 1 ATOM 379 O OD1 . ASP A 1 45 ? 3.372 27.726 -1.241 1.00 378.58 ? 761 ASP A OD1 1 ATOM 380 O OD2 . ASP A 1 45 ? 2.656 29.446 -0.081 1.00 376.63 ? 761 ASP A OD2 1 ATOM 381 N N . GLY A 1 46 ? -0.980 25.933 -2.284 1.00 368.68 ? 762 GLY A N 1 ATOM 382 C CA . GLY A 1 46 ? -2.399 25.652 -2.354 1.00 370.13 ? 762 GLY A CA 1 ATOM 383 C C . GLY A 1 46 ? -2.877 24.890 -3.569 1.00 369.60 ? 762 GLY A C 1 ATOM 384 O O . GLY A 1 46 ? -4.087 24.679 -3.701 1.00 372.20 ? 762 GLY A O 1 ATOM 385 N N . LEU A 1 47 ? -1.985 24.471 -4.461 1.00 375.00 ? 763 LEU A N 1 ATOM 386 C CA . LEU A 1 47 ? -2.370 23.696 -5.634 1.00 370.86 ? 763 LEU A CA 1 ATOM 387 C C . LEU A 1 47 ? -1.841 22.274 -5.498 1.00 366.96 ? 763 LEU A C 1 ATOM 388 O O . LEU A 1 47 ? -0.671 22.068 -5.159 1.00 362.06 ? 763 LEU A O 1 ATOM 389 C CB . LEU A 1 47 ? -1.872 24.352 -6.927 1.00 372.06 ? 763 LEU A CB 1 ATOM 390 C CG . LEU A 1 47 ? -0.390 24.649 -7.158 1.00 373.93 ? 763 LEU A CG 1 ATOM 391 C CD1 . LEU A 1 47 ? 0.282 23.510 -7.909 1.00 374.06 ? 763 LEU A CD1 1 ATOM 392 C CD2 . LEU A 1 47 ? -0.233 25.958 -7.918 1.00 374.87 ? 763 LEU A CD2 1 ATOM 393 N N . LEU A 1 48 ? -2.711 21.300 -5.761 1.00 366.27 ? 764 LEU A N 1 ATOM 394 C CA . LEU A 1 48 ? -2.452 19.888 -5.495 1.00 367.98 ? 764 LEU A CA 1 ATOM 395 C C . LEU A 1 48 ? -2.197 19.172 -6.817 1.00 369.34 ? 764 LEU A C 1 ATOM 396 O O . LEU A 1 48 ? -3.105 19.046 -7.646 1.00 372.80 ? 764 LEU A O 1 ATOM 397 C CB . LEU A 1 48 ? -3.633 19.271 -4.748 1.00 367.63 ? 764 LEU A CB 1 ATOM 398 C CG . LEU A 1 48 ? -3.603 17.782 -4.404 1.00 367.75 ? 764 LEU A CG 1 ATOM 399 C CD1 . LEU A 1 48 ? -2.463 17.476 -3.450 1.00 368.66 ? 764 LEU A CD1 1 ATOM 400 C CD2 . LEU A 1 48 ? -4.936 17.358 -3.806 1.00 366.04 ? 764 LEU A CD2 1 ATOM 401 N N . VAL A 1 49 ? -0.969 18.697 -7.006 1.00 370.87 ? 765 VAL A N 1 ATOM 402 C CA . VAL A 1 49 ? -0.562 18.013 -8.228 1.00 369.92 ? 765 VAL A CA 1 ATOM 403 C C . VAL A 1 49 ? -0.527 16.516 -7.954 1.00 374.03 ? 765 VAL A C 1 ATOM 404 O O . VAL A 1 49 ? 0.227 16.051 -7.089 1.00 379.73 ? 765 VAL A O 1 ATOM 405 C CB . VAL A 1 49 ? 0.802 18.517 -8.726 1.00 366.02 ? 765 VAL A CB 1 ATOM 406 C CG1 . VAL A 1 49 ? 1.216 17.770 -9.984 1.00 366.16 ? 765 VAL A CG1 1 ATOM 407 C CG2 . VAL A 1 49 ? 0.750 20.013 -8.983 1.00 363.53 ? 765 VAL A CG2 1 ATOM 408 N N . ILE A 1 50 ? -1.335 15.762 -8.694 1.00 367.40 ? 766 ILE A N 1 ATOM 409 C CA . ILE A 1 50 ? -1.449 14.317 -8.510 1.00 366.87 ? 766 ILE A CA 1 ATOM 410 C C . ILE A 1 50 ? -1.135 13.618 -9.827 1.00 363.09 ? 766 ILE A C 1 ATOM 411 O O . ILE A 1 50 ? -1.929 13.702 -10.776 1.00 366.53 ? 766 ILE A O 1 ATOM 412 C CB . ILE A 1 50 ? -2.850 13.933 -8.006 1.00 370.31 ? 766 ILE A CB 1 ATOM 413 C CG1 . ILE A 1 50 ? -3.139 14.606 -6.661 1.00 374.64 ? 766 ILE A CG1 1 ATOM 414 C CG2 . ILE A 1 50 ? -2.985 12.421 -7.895 1.00 371.72 ? 766 ILE A CG2 1 ATOM 415 C CD1 . ILE A 1 50 ? -4.566 14.430 -6.183 1.00 376.52 ? 766 ILE A CD1 1 ATOM 416 N N . PRO A 1 51 ? -0.000 12.930 -9.938 1.00 364.07 ? 767 PRO A N 1 ATOM 417 C CA . PRO A 1 51 ? 0.294 12.194 -11.175 1.00 363.81 ? 767 PRO A CA 1 ATOM 418 C C . PRO A 1 51 ? -0.692 11.055 -11.392 1.00 365.73 ? 767 PRO A C 1 ATOM 419 O O . PRO A 1 51 ? -1.031 10.314 -10.467 1.00 374.46 ? 767 PRO A O 1 ATOM 420 C CB . PRO A 1 51 ? 1.720 11.675 -10.953 1.00 362.92 ? 767 PRO A CB 1 ATOM 421 C CG . PRO A 1 51 ? 1.917 11.706 -9.469 1.00 364.59 ? 767 PRO A CG 1 ATOM 422 C CD . PRO A 1 51 ? 1.116 12.871 -8.980 1.00 364.80 ? 767 PRO A CD 1 ATOM 423 N N . LEU A 1 52 ? -1.151 10.923 -12.637 1.00 367.47 ? 768 LEU A N 1 ATOM 424 C CA . LEU A 1 52 ? -2.119 9.898 -12.988 1.00 367.46 ? 768 LEU A CA 1 ATOM 425 C C . LEU A 1 52 ? -1.490 8.509 -12.887 1.00 369.21 ? 768 LEU A C 1 ATOM 426 O O . LEU A 1 52 ? -0.268 8.365 -12.965 1.00 370.38 ? 768 LEU A O 1 ATOM 427 C CB . LEU A 1 52 ? -2.658 10.142 -14.398 1.00 368.20 ? 768 LEU A CB 1 ATOM 428 C CG . LEU A 1 52 ? -3.851 11.095 -14.537 1.00 368.95 ? 768 LEU A CG 1 ATOM 429 C CD1 . LEU A 1 52 ? -3.479 12.524 -14.167 1.00 371.63 ? 768 LEU A CD1 1 ATOM 430 C CD2 . LEU A 1 52 ? -4.433 11.039 -15.943 1.00 365.73 ? 768 LEU A CD2 1 ATOM 431 N N . PRO A 1 53 ? -2.307 7.470 -12.707 1.00 367.94 ? 769 PRO A N 1 ATOM 432 C CA . PRO A 1 53 ? -1.756 6.122 -12.534 1.00 369.90 ? 769 PRO A CA 1 ATOM 433 C C . PRO A 1 53 ? -1.022 5.633 -13.774 1.00 368.40 ? 769 PRO A C 1 ATOM 434 O O . PRO A 1 53 ? -1.182 6.150 -14.879 1.00 364.89 ? 769 PRO A O 1 ATOM 435 C CB . PRO A 1 53 ? -2.996 5.264 -12.249 1.00 372.16 ? 769 PRO A CB 1 ATOM 436 C CG . PRO A 1 53 ? -4.137 6.046 -12.799 1.00 371.43 ? 769 PRO A CG 1 ATOM 437 C CD . PRO A 1 53 ? -3.774 7.480 -12.570 1.00 369.00 ? 769 PRO A CD 1 ATOM 438 N N . VAL A 1 54 ? -0.205 4.595 -13.561 1.00 375.49 ? 770 VAL A N 1 ATOM 439 C CA . VAL A 1 54 ? 0.685 4.069 -14.593 1.00 378.15 ? 770 VAL A CA 1 ATOM 440 C C . VAL A 1 54 ? -0.097 3.492 -15.763 1.00 378.15 ? 770 VAL A C 1 ATOM 441 O O . VAL A 1 54 ? 0.441 3.372 -16.871 1.00 375.27 ? 770 VAL A O 1 ATOM 442 C CB . VAL A 1 54 ? 1.641 3.016 -13.984 1.00 380.90 ? 770 VAL A CB 1 ATOM 443 C CG1 . VAL A 1 54 ? 0.875 1.762 -13.580 1.00 383.06 ? 770 VAL A CG1 1 ATOM 444 C CG2 . VAL A 1 54 ? 2.776 2.684 -14.950 1.00 380.87 ? 770 VAL A CG2 1 ATOM 445 N N . GLU A 1 55 ? -1.371 3.147 -15.553 1.00 372.73 ? 771 GLU A N 1 ATOM 446 C CA . GLU A 1 55 ? -2.190 2.662 -16.659 1.00 377.82 ? 771 GLU A CA 1 ATOM 447 C C . GLU A 1 55 ? -2.435 3.761 -17.682 1.00 375.55 ? 771 GLU A C 1 ATOM 448 O O . GLU A 1 55 ? -2.490 3.492 -18.887 1.00 375.65 ? 771 GLU A O 1 ATOM 449 C CB . GLU A 1 55 ? -3.523 2.115 -16.143 1.00 382.14 ? 771 GLU A CB 1 ATOM 450 C CG . GLU A 1 55 ? -3.415 0.962 -15.160 1.00 386.77 ? 771 GLU A CG 1 ATOM 451 C CD . GLU A 1 55 ? -3.402 1.425 -13.717 1.00 389.91 ? 771 GLU A CD 1 ATOM 452 O OE1 . GLU A 1 55 ? -2.466 1.051 -12.978 1.00 389.63 ? 771 GLU A OE1 1 ATOM 453 O OE2 . GLU A 1 55 ? -4.328 2.167 -13.323 1.00 390.78 ? 771 GLU A OE2 1 ATOM 454 N N . GLU A 1 56 ? -2.579 5.005 -17.222 1.00 374.87 ? 772 GLU A N 1 ATOM 455 C CA . GLU A 1 56 ? -2.863 6.121 -18.114 1.00 372.26 ? 772 GLU A CA 1 ATOM 456 C C . GLU A 1 56 ? -1.610 6.715 -18.741 1.00 368.76 ? 772 GLU A C 1 ATOM 457 O O . GLU A 1 56 ? -1.708 7.376 -19.781 1.00 370.95 ? 772 GLU A O 1 ATOM 458 C CB . GLU A 1 56 ? -3.621 7.214 -17.356 1.00 374.27 ? 772 GLU A CB 1 ATOM 459 C CG . GLU A 1 56 ? -5.047 6.848 -16.983 1.00 378.47 ? 772 GLU A CG 1 ATOM 460 C CD . GLU A 1 56 ? -5.990 6.909 -18.168 1.00 385.56 ? 772 GLU A CD 1 ATOM 461 O OE1 . GLU A 1 56 ? -5.934 7.905 -18.921 1.00 390.34 ? 772 GLU A OE1 1 ATOM 462 O OE2 . GLU A 1 56 ? -6.780 5.960 -18.352 1.00 390.45 ? 772 GLU A OE2 1 ATOM 463 N N . GLN A 1 57 ? -0.444 6.502 -18.138 1.00 360.48 ? 773 GLN A N 1 ATOM 464 C CA . GLN A 1 57 ? 0.791 7.100 -18.631 1.00 359.24 ? 773 GLN A CA 1 ATOM 465 C C . GLN A 1 57 ? 1.316 6.326 -19.835 1.00 361.06 ? 773 GLN A C 1 ATOM 466 O O . GLN A 1 57 ? 1.404 5.095 -19.800 1.00 363.68 ? 773 GLN A O 1 ATOM 467 C CB . GLN A 1 57 ? 1.847 7.132 -17.526 1.00 358.56 ? 773 GLN A CB 1 ATOM 468 C CG . GLN A 1 57 ? 1.431 7.883 -16.268 1.00 357.34 ? 773 GLN A CG 1 ATOM 469 C CD . GLN A 1 57 ? 1.373 9.388 -16.463 1.00 355.02 ? 773 GLN A CD 1 ATOM 470 O OE1 . GLN A 1 57 ? 1.775 9.911 -17.502 1.00 352.00 ? 773 GLN A OE1 1 ATOM 471 N NE2 . GLN A 1 57 ? 0.873 10.093 -15.454 1.00 354.45 ? 773 GLN A NE2 1 ATOM 472 N N . CYS A 1 58 ? 1.670 7.058 -20.894 1.00 356.28 ? 774 CYS A N 1 ATOM 473 C CA . CYS A 1 58 ? 2.226 6.478 -22.121 1.00 356.95 ? 774 CYS A CA 1 ATOM 474 C C . CYS A 1 58 ? 1.286 5.425 -22.710 1.00 356.95 ? 774 CYS A C 1 ATOM 475 O O . CYS A 1 58 ? 1.674 4.286 -22.973 1.00 360.86 ? 774 CYS A O 1 ATOM 476 C CB . CYS A 1 58 ? 3.625 5.904 -21.870 1.00 357.44 ? 774 CYS A CB 1 ATOM 477 S SG . CYS A 1 58 ? 4.578 5.458 -23.355 1.00 364.83 ? 774 CYS A SG 1 ATOM 478 N N . ARG A 1 59 ? 0.031 5.817 -22.910 1.00 347.54 ? 775 ARG A N 1 ATOM 479 C CA . ARG A 1 59 ? -0.971 4.972 -23.544 1.00 351.19 ? 775 ARG A CA 1 ATOM 480 C C . ARG A 1 59 ? -1.499 5.679 -24.784 1.00 347.40 ? 775 ARG A C 1 ATOM 481 O O . ARG A 1 59 ? -1.807 6.874 -24.742 1.00 345.11 ? 775 ARG A O 1 ATOM 482 C CB . ARG A 1 59 ? -2.125 4.651 -22.589 1.00 359.62 ? 775 ARG A CB 1 ATOM 483 C CG . ARG A 1 59 ? -3.030 3.524 -23.068 1.00 368.67 ? 775 ARG A CG 1 ATOM 484 C CD . ARG A 1 59 ? -4.121 3.210 -22.055 1.00 373.55 ? 775 ARG A CD 1 ATOM 485 N NE . ARG A 1 59 ? -5.060 4.317 -21.897 1.00 377.99 ? 775 ARG A NE 1 ATOM 486 C CZ . ARG A 1 59 ? -6.182 4.449 -22.597 1.00 379.95 ? 775 ARG A CZ 1 ATOM 487 N NH1 . ARG A 1 59 ? -6.507 3.541 -23.506 1.00 384.47 ? 775 ARG A NH1 1 ATOM 488 N NH2 . ARG A 1 59 ? -6.980 5.488 -22.388 1.00 378.12 ? 775 ARG A NH2 1 ATOM 489 N N . GLY A 1 60 ? -1.598 4.940 -25.880 1.00 343.34 ? 776 GLY A N 1 ATOM 490 C CA . GLY A 1 60 ? -2.050 5.487 -27.153 1.00 340.81 ? 776 GLY A CA 1 ATOM 491 C C . GLY A 1 60 ? -3.370 4.871 -27.572 1.00 337.88 ? 776 GLY A C 1 ATOM 492 O O . GLY A 1 60 ? -3.616 3.686 -27.329 1.00 343.49 ? 776 GLY A O 1 ATOM 493 N N . VAL A 1 61 ? -4.223 5.682 -28.195 1.00 332.01 ? 777 VAL A N 1 ATOM 494 C CA . VAL A 1 61 ? -5.528 5.234 -28.670 1.00 329.98 ? 777 VAL A CA 1 ATOM 495 C C . VAL A 1 61 ? -5.652 5.575 -30.150 1.00 327.37 ? 777 VAL A C 1 ATOM 496 O O . VAL A 1 61 ? -5.339 6.696 -30.566 1.00 327.88 ? 777 VAL A O 1 ATOM 497 C CB . VAL A 1 61 ? -6.684 5.855 -27.857 1.00 330.20 ? 777 VAL A CB 1 ATOM 498 C CG1 . VAL A 1 61 ? -6.610 5.400 -26.404 1.00 332.60 ? 777 VAL A CG1 1 ATOM 499 C CG2 . VAL A 1 61 ? -6.662 7.377 -27.937 1.00 331.01 ? 777 VAL A CG2 1 ATOM 500 N N . LEU A 1 62 ? -6.081 4.598 -30.944 1.00 315.74 ? 778 LEU A N 1 ATOM 501 C CA . LEU A 1 62 ? -6.326 4.786 -32.367 1.00 315.25 ? 778 LEU A CA 1 ATOM 502 C C . LEU A 1 62 ? -7.830 4.862 -32.594 1.00 318.46 ? 778 LEU A C 1 ATOM 503 O O . LEU A 1 62 ? -8.553 3.901 -32.313 1.00 319.85 ? 778 LEU A O 1 ATOM 504 C CB . LEU A 1 62 ? -5.715 3.649 -33.185 1.00 311.68 ? 778 LEU A CB 1 ATOM 505 C CG . LEU A 1 62 ? -5.982 3.670 -34.692 1.00 309.82 ? 778 LEU A CG 1 ATOM 506 C CD1 . LEU A 1 62 ? -5.316 4.872 -35.349 1.00 310.18 ? 778 LEU A CD1 1 ATOM 507 C CD2 . LEU A 1 62 ? -5.521 2.374 -35.341 1.00 310.02 ? 778 LEU A CD2 1 ATOM 508 N N . SER A 1 63 ? -8.294 6.001 -33.095 1.00 299.28 ? 779 SER A N 1 ATOM 509 C CA . SER A 1 63 ? -9.715 6.194 -33.323 1.00 301.96 ? 779 SER A CA 1 ATOM 510 C C . SER A 1 63 ? -10.182 5.361 -34.514 1.00 302.79 ? 779 SER A C 1 ATOM 511 O O . SER A 1 63 ? -9.384 4.830 -35.290 1.00 295.95 ? 779 SER A O 1 ATOM 512 C CB . SER A 1 63 ? -10.022 7.674 -33.549 1.00 306.69 ? 779 SER A CB 1 ATOM 513 O OG . SER A 1 63 ? -9.529 8.469 -32.483 1.00 314.87 ? 779 SER A OG 1 ATOM 514 N N . GLU A 1 64 ? -11.498 5.239 -34.645 1.00 297.88 ? 780 GLU A N 1 ATOM 515 C CA . GLU A 1 64 ? -12.052 4.581 -35.814 1.00 298.57 ? 780 GLU A CA 1 ATOM 516 C C . GLU A 1 64 ? -11.997 5.516 -37.020 1.00 291.96 ? 780 GLU A C 1 ATOM 517 O O . GLU A 1 64 ? -12.093 6.737 -36.871 1.00 291.21 ? 780 GLU A O 1 ATOM 518 C CB . GLU A 1 64 ? -13.493 4.153 -35.554 1.00 306.13 ? 780 GLU A CB 1 ATOM 519 C CG . GLU A 1 64 ? -13.635 3.083 -34.483 1.00 314.93 ? 780 GLU A CG 1 ATOM 520 C CD . GLU A 1 64 ? -13.056 1.747 -34.910 1.00 322.86 ? 780 GLU A CD 1 ATOM 521 O OE1 . GLU A 1 64 ? -13.122 1.427 -36.117 1.00 326.99 ? 780 GLU A OE1 1 ATOM 522 O OE2 . GLU A 1 64 ? -12.533 1.020 -34.040 1.00 330.83 ? 780 GLU A OE2 1 ATOM 523 N N . PRO A 1 65 ? -11.832 4.968 -38.222 1.00 298.65 ? 781 PRO A N 1 ATOM 524 C CA . PRO A 1 65 ? -11.750 5.822 -39.412 1.00 299.06 ? 781 PRO A CA 1 ATOM 525 C C . PRO A 1 65 ? -13.083 6.476 -39.735 1.00 303.77 ? 781 PRO A C 1 ATOM 526 O O . PRO A 1 65 ? -14.145 5.856 -39.635 1.00 308.26 ? 781 PRO A O 1 ATOM 527 C CB . PRO A 1 65 ? -11.327 4.850 -40.517 1.00 296.40 ? 781 PRO A CB 1 ATOM 528 C CG . PRO A 1 65 ? -11.772 3.514 -40.038 1.00 295.56 ? 781 PRO A CG 1 ATOM 529 C CD . PRO A 1 65 ? -11.628 3.545 -38.545 1.00 296.60 ? 781 PRO A CD 1 ATOM 530 N N . LEU A 1 66 ? -13.011 7.738 -40.136 1.00 300.72 ? 782 LEU A N 1 ATOM 531 C CA . LEU A 1 66 ? -14.169 8.531 -40.514 1.00 299.94 ? 782 LEU A CA 1 ATOM 532 C C . LEU A 1 66 ? -13.797 9.375 -41.721 1.00 297.20 ? 782 LEU A C 1 ATOM 533 O O . LEU A 1 66 ? -12.613 9.637 -41.960 1.00 294.68 ? 782 LEU A O 1 ATOM 534 C CB . LEU A 1 66 ? -14.632 9.435 -39.363 1.00 299.99 ? 782 LEU A CB 1 ATOM 535 C CG . LEU A 1 66 ? -15.081 8.750 -38.071 1.00 298.69 ? 782 LEU A CG 1 ATOM 536 C CD1 . LEU A 1 66 ? -15.342 9.782 -36.987 1.00 298.98 ? 782 LEU A CD1 1 ATOM 537 C CD2 . LEU A 1 66 ? -16.319 7.903 -38.314 1.00 299.15 ? 782 LEU A CD2 1 ATOM 538 N N . PRO A 1 67 ? -14.782 9.802 -42.510 1.00 291.64 ? 783 PRO A N 1 ATOM 539 C CA . PRO A 1 67 ? -14.483 10.721 -43.614 1.00 292.52 ? 783 PRO A CA 1 ATOM 540 C C . PRO A 1 67 ? -13.974 12.057 -43.094 1.00 293.48 ? 783 PRO A C 1 ATOM 541 O O . PRO A 1 67 ? -14.336 12.504 -42.003 1.00 296.55 ? 783 PRO A O 1 ATOM 542 C CB . PRO A 1 67 ? -15.832 10.872 -44.329 1.00 292.00 ? 783 PRO A CB 1 ATOM 543 C CG . PRO A 1 67 ? -16.854 10.472 -43.311 1.00 293.51 ? 783 PRO A CG 1 ATOM 544 C CD . PRO A 1 67 ? -16.199 9.403 -42.494 1.00 293.11 ? 783 PRO A CD 1 ATOM 545 N N . ASP A 1 68 ? -13.114 12.688 -43.888 1.00 291.72 ? 784 ASP A N 1 ATOM 546 C CA . ASP A 1 68 ? -12.565 13.997 -43.546 1.00 292.30 ? 784 ASP A CA 1 ATOM 547 C C . ASP A 1 68 ? -13.677 15.030 -43.672 1.00 294.65 ? 784 ASP A C 1 ATOM 548 O O . ASP A 1 68 ? -14.069 15.410 -44.778 1.00 298.21 ? 784 ASP A O 1 ATOM 549 C CB . ASP A 1 68 ? -11.385 14.333 -44.452 1.00 293.93 ? 784 ASP A CB 1 ATOM 550 C CG . ASP A 1 68 ? -10.540 15.477 -43.917 1.00 296.05 ? 784 ASP A CG 1 ATOM 551 O OD1 . ASP A 1 68 ? -11.059 16.292 -43.125 1.00 299.53 ? 784 ASP A OD1 1 ATOM 552 O OD2 . ASP A 1 68 ? -9.352 15.562 -44.293 1.00 297.57 ? 784 ASP A OD2 1 ATOM 553 N N . LEU A 1 69 ? -14.196 15.486 -42.529 1.00 295.09 ? 785 LEU A N 1 ATOM 554 C CA . LEU A 1 69 ? -15.306 16.434 -42.541 1.00 296.40 ? 785 LEU A CA 1 ATOM 555 C C . LEU A 1 69 ? -14.904 17.771 -43.145 1.00 298.07 ? 785 LEU A C 1 ATOM 556 O O . LEU A 1 69 ? -15.750 18.467 -43.718 1.00 302.77 ? 785 LEU A O 1 ATOM 557 C CB . LEU A 1 69 ? -15.843 16.632 -41.124 1.00 296.27 ? 785 LEU A CB 1 ATOM 558 C CG . LEU A 1 69 ? -16.386 15.390 -40.417 1.00 295.99 ? 785 LEU A CG 1 ATOM 559 C CD1 . LEU A 1 69 ? -16.934 15.753 -39.046 1.00 297.07 ? 785 LEU A CD1 1 ATOM 560 C CD2 . LEU A 1 69 ? -17.453 14.717 -41.265 1.00 298.74 ? 785 LEU A CD2 1 ATOM 561 N N . GLN A 1 70 ? -13.628 18.147 -43.027 1.00 301.54 ? 786 GLN A N 1 ATOM 562 C CA . GLN A 1 70 ? -13.167 19.401 -43.613 1.00 304.96 ? 786 GLN A CA 1 ATOM 563 C C . GLN A 1 70 ? -13.307 19.395 -45.128 1.00 300.05 ? 786 GLN A C 1 ATOM 564 O O . GLN A 1 70 ? -13.524 20.449 -45.738 1.00 300.96 ? 786 GLN A O 1 ATOM 565 C CB . GLN A 1 70 ? -11.711 19.664 -43.224 1.00 312.70 ? 786 GLN A CB 1 ATOM 566 C CG . GLN A 1 70 ? -11.416 19.495 -41.741 1.00 320.11 ? 786 GLN A CG 1 ATOM 567 C CD . GLN A 1 70 ? -12.215 20.443 -40.867 1.00 328.64 ? 786 GLN A CD 1 ATOM 568 O OE1 . GLN A 1 70 ? -12.561 21.550 -41.282 1.00 336.82 ? 786 GLN A OE1 1 ATOM 569 N NE2 . GLN A 1 70 ? -12.514 20.010 -39.647 1.00 330.52 ? 786 GLN A NE2 1 ATOM 570 N N . LEU A 1 71 ? -13.188 18.223 -45.752 1.00 303.94 ? 787 LEU A N 1 ATOM 571 C CA . LEU A 1 71 ? -13.290 18.082 -47.196 1.00 299.61 ? 787 LEU A CA 1 ATOM 572 C C . LEU A 1 71 ? -14.714 17.794 -47.660 1.00 299.39 ? 787 LEU A C 1 ATOM 573 O O . LEU A 1 71 ? -14.902 17.245 -48.752 1.00 296.40 ? 787 LEU A O 1 ATOM 574 C CB . LEU A 1 71 ? -12.343 16.983 -47.681 1.00 296.99 ? 787 LEU A CB 1 ATOM 575 C CG . LEU A 1 71 ? -10.872 17.171 -47.301 1.00 294.11 ? 787 LEU A CG 1 ATOM 576 C CD1 . LEU A 1 71 ? -10.030 15.990 -47.762 1.00 294.93 ? 787 LEU A CD1 1 ATOM 577 C CD2 . LEU A 1 71 ? -10.332 18.473 -47.873 1.00 293.66 ? 787 LEU A CD2 1 ATOM 578 N N . LEU A 1 72 ? -15.719 18.152 -46.857 1.00 300.95 ? 788 LEU A N 1 ATOM 579 C CA . LEU A 1 72 ? -17.118 17.970 -47.231 1.00 300.71 ? 788 LEU A CA 1 ATOM 580 C C . LEU A 1 72 ? -17.924 19.257 -47.073 1.00 302.76 ? 788 LEU A C 1 ATOM 581 O O . LEU A 1 72 ? -19.156 19.204 -47.021 1.00 302.65 ? 788 LEU A O 1 ATOM 582 C CB . LEU A 1 72 ? -17.761 16.851 -46.406 1.00 298.32 ? 788 LEU A CB 1 ATOM 583 C CG . LEU A 1 72 ? -17.159 15.445 -46.474 1.00 296.48 ? 788 LEU A CG 1 ATOM 584 C CD1 . LEU A 1 72 ? -17.913 14.499 -45.545 1.00 296.62 ? 788 LEU A CD1 1 ATOM 585 C CD2 . LEU A 1 72 ? -17.166 14.918 -47.898 1.00 297.49 ? 788 LEU A CD2 1 ATOM 586 N N . THR A 1 73 ? -17.256 20.413 -47.019 1.00 310.18 ? 789 THR A N 1 ATOM 587 C CA . THR A 1 73 ? -17.910 21.675 -46.690 1.00 316.65 ? 789 THR A CA 1 ATOM 588 C C . THR A 1 73 ? -17.908 22.709 -47.810 1.00 314.50 ? 789 THR A C 1 ATOM 589 O O . THR A 1 73 ? -18.878 23.458 -47.930 1.00 325.16 ? 789 THR A O 1 ATOM 590 C CB . THR A 1 73 ? -17.254 22.307 -45.456 1.00 321.34 ? 789 THR A CB 1 ATOM 591 O OG1 . THR A 1 73 ? -15.937 22.757 -45.793 1.00 329.15 ? 789 THR A OG1 1 ATOM 592 C CG2 . THR A 1 73 ? -17.163 21.298 -44.325 1.00 322.67 ? 789 THR A CG2 1 ATOM 593 N N . GLY A 1 74 ? -16.849 22.797 -48.614 1.00 324.10 ? 790 GLY A N 1 ATOM 594 C CA . GLY A 1 74 ? -16.782 23.820 -49.643 1.00 326.46 ? 790 GLY A CA 1 ATOM 595 C C . GLY A 1 74 ? -16.991 23.316 -51.060 1.00 328.79 ? 790 GLY A C 1 ATOM 596 O O . GLY A 1 74 ? -18.059 22.793 -51.390 1.00 328.49 ? 790 GLY A O 1 ATOM 597 N N . ASP A 1 75 ? -15.984 23.501 -51.914 1.00 332.31 ? 791 ASP A N 1 ATOM 598 C CA . ASP A 1 75 ? -15.990 22.900 -53.244 1.00 329.98 ? 791 ASP A CA 1 ATOM 599 C C . ASP A 1 75 ? -15.606 21.441 -53.073 1.00 326.31 ? 791 ASP A C 1 ATOM 600 O O . ASP A 1 75 ? -14.430 21.106 -52.911 1.00 327.50 ? 791 ASP A O 1 ATOM 601 C CB . ASP A 1 75 ? -15.038 23.634 -54.185 1.00 335.15 ? 791 ASP A CB 1 ATOM 602 C CG . ASP A 1 75 ? -15.533 25.021 -54.526 1.00 342.22 ? 791 ASP A CG 1 ATOM 603 O OD1 . ASP A 1 75 ? -16.263 25.603 -53.703 1.00 351.12 ? 791 ASP A OD1 1 ATOM 604 O OD2 . ASP A 1 75 ? -15.200 25.525 -55.618 1.00 348.85 ? 791 ASP A OD2 1 ATOM 605 N N . ILE A 1 76 ? -16.606 20.568 -53.099 1.00 334.18 ? 792 ILE A N 1 ATOM 606 C CA . ILE A 1 76 ? -16.432 19.188 -52.664 1.00 335.00 ? 792 ILE A CA 1 ATOM 607 C C . ILE A 1 76 ? -15.943 18.343 -53.814 1.00 336.67 ? 792 ILE A C 1 ATOM 608 O O . ILE A 1 76 ? -16.642 18.181 -54.816 1.00 339.53 ? 792 ILE A O 1 ATOM 609 C CB . ILE A 1 76 ? -17.730 18.594 -52.114 1.00 334.16 ? 792 ILE A CB 1 ATOM 610 C CG1 . ILE A 1 76 ? -18.318 19.536 -51.070 1.00 335.15 ? 792 ILE A CG1 1 ATOM 611 C CG2 . ILE A 1 76 ? -17.415 17.210 -51.546 1.00 333.19 ? 792 ILE A CG2 1 ATOM 612 C CD1 . ILE A 1 76 ? -17.262 20.025 -50.154 1.00 336.18 ? 792 ILE A CD1 1 ATOM 613 N N . ARG A 1 77 ? -14.792 17.721 -53.642 1.00 327.78 ? 793 ARG A N 1 ATOM 614 C CA . ARG A 1 77 ? -14.171 17.104 -54.796 1.00 329.56 ? 793 ARG A CA 1 ATOM 615 C C . ARG A 1 77 ? -13.249 15.967 -54.400 1.00 327.62 ? 793 ARG A C 1 ATOM 616 O O . ARG A 1 77 ? -12.370 16.146 -53.550 1.00 332.33 ? 793 ARG A O 1 ATOM 617 C CB . ARG A 1 77 ? -13.432 18.176 -55.587 1.00 335.14 ? 793 ARG A CB 1 ATOM 618 C CG . ARG A 1 77 ? -14.356 18.809 -56.646 1.00 342.28 ? 793 ARG A CG 1 ATOM 619 C CD . ARG A 1 77 ? -14.580 20.294 -56.455 1.00 345.57 ? 793 ARG A CD 1 ATOM 620 N NE . ARG A 1 77 ? -15.072 20.906 -57.666 1.00 349.04 ? 793 ARG A NE 1 ATOM 621 C CZ . ARG A 1 77 ? -16.075 21.767 -57.692 1.00 348.37 ? 793 ARG A CZ 1 ATOM 622 N NH1 . ARG A 1 77 ? -16.697 22.104 -56.575 1.00 344.21 ? 793 ARG A NH1 1 ATOM 623 N NH2 . ARG A 1 77 ? -16.461 22.275 -58.849 1.00 351.94 ? 793 ARG A NH2 1 ATOM 624 N N . TYR A 1 78 ? -13.443 14.826 -55.063 1.00 321.63 ? 794 TYR A N 1 ATOM 625 C CA . TYR A 1 78 ? -12.835 13.545 -54.746 1.00 323.28 ? 794 TYR A CA 1 ATOM 626 C C . TYR A 1 78 ? -13.076 12.620 -55.928 1.00 327.51 ? 794 TYR A C 1 ATOM 627 O O . TYR A 1 78 ? -14.049 12.788 -56.668 1.00 332.42 ? 794 TYR A O 1 ATOM 628 C CB . TYR A 1 78 ? -13.435 12.952 -53.465 1.00 324.41 ? 794 TYR A CB 1 ATOM 629 C CG . TYR A 1 78 ? -14.914 12.660 -53.582 1.00 325.48 ? 794 TYR A CG 1 ATOM 630 C CD1 . TYR A 1 78 ? -15.356 11.407 -53.980 1.00 326.50 ? 794 TYR A CD1 1 ATOM 631 C CD2 . TYR A 1 78 ? -15.866 13.633 -53.298 1.00 324.52 ? 794 TYR A CD2 1 ATOM 632 C CE1 . TYR A 1 78 ? -16.693 11.126 -54.092 1.00 328.78 ? 794 TYR A CE1 1 ATOM 633 C CE2 . TYR A 1 78 ? -17.217 13.359 -53.408 1.00 325.45 ? 794 TYR A CE2 1 ATOM 634 C CZ . TYR A 1 78 ? -17.622 12.099 -53.806 1.00 327.23 ? 794 TYR A CZ 1 ATOM 635 O OH . TYR A 1 78 ? -18.958 11.802 -53.921 1.00 325.76 ? 794 TYR A OH 1 ATOM 636 N N . ASP A 1 79 ? -12.181 11.653 -56.103 1.00 329.45 ? 795 ASP A N 1 ATOM 637 C CA . ASP A 1 79 ? -12.357 10.658 -57.156 1.00 332.42 ? 795 ASP A CA 1 ATOM 638 C C . ASP A 1 79 ? -13.578 9.799 -56.852 1.00 334.38 ? 795 ASP A C 1 ATOM 639 O O . ASP A 1 79 ? -13.693 9.223 -55.765 1.00 338.87 ? 795 ASP A O 1 ATOM 640 C CB . ASP A 1 79 ? -11.108 9.782 -57.284 1.00 334.96 ? 795 ASP A CB 1 ATOM 641 C CG . ASP A 1 79 ? -11.087 8.964 -58.569 1.00 339.68 ? 795 ASP A CG 1 ATOM 642 O OD1 . ASP A 1 79 ? -12.167 8.594 -59.082 1.00 346.79 ? 795 ASP A OD1 1 ATOM 643 O OD2 . ASP A 1 79 ? -9.982 8.687 -59.083 1.00 340.92 ? 795 ASP A OD2 1 ATOM 644 N N . GLU A 1 80 ? -14.491 9.724 -57.825 1.00 335.31 ? 796 GLU A N 1 ATOM 645 C CA . GLU A 1 80 ? -15.707 8.937 -57.661 1.00 334.65 ? 796 GLU A CA 1 ATOM 646 C C . GLU A 1 80 ? -15.390 7.475 -57.375 1.00 336.96 ? 796 GLU A C 1 ATOM 647 O O . GLU A 1 80 ? -16.081 6.823 -56.583 1.00 337.31 ? 796 GLU A O 1 ATOM 648 C CB . GLU A 1 80 ? -16.573 9.062 -58.914 1.00 334.43 ? 796 GLU A CB 1 ATOM 649 C CG . GLU A 1 80 ? -17.827 8.206 -58.902 1.00 336.43 ? 796 GLU A CG 1 ATOM 650 C CD . GLU A 1 80 ? -18.479 8.111 -60.268 1.00 336.93 ? 796 GLU A CD 1 ATOM 651 O OE1 . GLU A 1 80 ? -19.154 7.094 -60.536 1.00 340.21 ? 796 GLU A OE1 1 ATOM 652 O OE2 . GLU A 1 80 ? -18.315 9.051 -61.075 1.00 332.80 ? 796 GLU A OE2 1 ATOM 653 N N . ALA A 1 81 ? -14.346 6.943 -58.013 1.00 334.81 ? 797 ALA A N 1 ATOM 654 C CA . ALA A 1 81 ? -13.961 5.558 -57.773 1.00 337.61 ? 797 ALA A CA 1 ATOM 655 C C . ALA A 1 81 ? -13.383 5.368 -56.376 1.00 340.53 ? 797 ALA A C 1 ATOM 656 O O . ALA A 1 81 ? -13.537 4.295 -55.782 1.00 346.66 ? 797 ALA A O 1 ATOM 657 C CB . ALA A 1 81 ? -12.960 5.103 -58.834 1.00 335.75 ? 797 ALA A CB 1 ATOM 658 N N . MET A 1 82 ? -12.723 6.394 -55.838 1.00 322.90 ? 798 MET A N 1 ATOM 659 C CA . MET A 1 82 ? -12.133 6.290 -54.506 1.00 324.57 ? 798 MET A CA 1 ATOM 660 C C . MET A 1 82 ? -13.202 6.332 -53.423 1.00 321.06 ? 798 MET A C 1 ATOM 661 O O . MET A 1 82 ? -13.278 5.434 -52.573 1.00 328.28 ? 798 MET A O 1 ATOM 662 C CB . MET A 1 82 ? -11.117 7.415 -54.291 1.00 327.95 ? 798 MET A CB 1 ATOM 663 C CG . MET A 1 82 ? -9.868 7.334 -55.148 1.00 331.04 ? 798 MET A CG 1 ATOM 664 S SD . MET A 1 82 ? -8.615 6.206 -54.517 1.00 338.77 ? 798 MET A SD 1 ATOM 665 C CE . MET A 1 82 ? -7.145 6.923 -55.248 1.00 341.71 ? 798 MET A CE 1 ATOM 666 N N . GLY A 1 83 ? -14.035 7.362 -53.442 1.00 331.51 ? 799 GLY A N 1 ATOM 667 C CA . GLY A 1 83 ? -14.970 7.651 -52.375 1.00 330.90 ? 799 GLY A CA 1 ATOM 668 C C . GLY A 1 83 ? -14.518 8.852 -51.563 1.00 329.42 ? 799 GLY A C 1 ATOM 669 O O . GLY A 1 83 ? -13.648 9.623 -51.969 1.00 326.97 ? 799 GLY A O 1 ATOM 670 N N . TYR A 1 84 ? -15.127 8.997 -50.392 1.00 314.08 ? 800 TYR A N 1 ATOM 671 C CA . TYR A 1 84 ? -14.735 10.073 -49.491 1.00 309.99 ? 800 TYR A CA 1 ATOM 672 C C . TYR A 1 84 ? -13.290 9.881 -49.038 1.00 306.30 ? 800 TYR A C 1 ATOM 673 O O . TYR A 1 84 ? -12.867 8.748 -48.771 1.00 304.33 ? 800 TYR A O 1 ATOM 674 C CB . TYR A 1 84 ? -15.644 10.119 -48.261 1.00 310.14 ? 800 TYR A CB 1 ATOM 675 C CG . TYR A 1 84 ? -17.009 10.733 -48.475 1.00 309.00 ? 800 TYR A CG 1 ATOM 676 C CD1 . TYR A 1 84 ? -17.267 11.560 -49.561 1.00 307.92 ? 800 TYR A CD1 1 ATOM 677 C CD2 . TYR A 1 84 ? -18.039 10.495 -47.574 1.00 309.82 ? 800 TYR A CD2 1 ATOM 678 C CE1 . TYR A 1 84 ? -18.520 12.122 -49.747 1.00 309.00 ? 800 TYR A CE1 1 ATOM 679 C CE2 . TYR A 1 84 ? -19.290 11.051 -47.751 1.00 310.02 ? 800 TYR A CE2 1 ATOM 680 C CZ . TYR A 1 84 ? -19.527 11.863 -48.837 1.00 309.54 ? 800 TYR A CZ 1 ATOM 681 O OH . TYR A 1 84 ? -20.774 12.415 -49.009 1.00 312.71 ? 800 TYR A OH 1 ATOM 682 N N . PRO A 1 85 ? -12.505 10.952 -48.948 1.00 298.33 ? 801 PRO A N 1 ATOM 683 C CA . PRO A 1 85 ? -11.214 10.853 -48.257 1.00 298.40 ? 801 PRO A CA 1 ATOM 684 C C . PRO A 1 85 ? -11.427 10.607 -46.771 1.00 298.99 ? 801 PRO A C 1 ATOM 685 O O . PRO A 1 85 ? -12.319 11.188 -46.148 1.00 300.61 ? 801 PRO A O 1 ATOM 686 C CB . PRO A 1 85 ? -10.563 12.219 -48.515 1.00 297.63 ? 801 PRO A CB 1 ATOM 687 C CG . PRO A 1 85 ? -11.265 12.758 -49.722 1.00 298.93 ? 801 PRO A CG 1 ATOM 688 C CD . PRO A 1 85 ? -12.673 12.250 -49.620 1.00 299.78 ? 801 PRO A CD 1 ATOM 689 N N . MET A 1 86 ? -10.603 9.730 -46.208 1.00 291.61 ? 802 MET A N 1 ATOM 690 C CA . MET A 1 86 ? -10.755 9.286 -44.831 1.00 290.74 ? 802 MET A CA 1 ATOM 691 C C . MET A 1 86 ? -9.651 9.857 -43.950 1.00 287.19 ? 802 MET A C 1 ATOM 692 O O . MET A 1 86 ? -8.562 10.201 -44.418 1.00 283.71 ? 802 MET A O 1 ATOM 693 C CB . MET A 1 86 ? -10.747 7.756 -44.749 1.00 291.45 ? 802 MET A CB 1 ATOM 694 C CG . MET A 1 86 ? -11.924 7.094 -45.441 1.00 293.03 ? 802 MET A CG 1 ATOM 695 S SD . MET A 1 86 ? -13.425 7.151 -44.445 1.00 298.78 ? 802 MET A SD 1 ATOM 696 C CE . MET A 1 86 ? -14.653 7.498 -45.701 1.00 300.69 ? 802 MET A CE 1 ATOM 697 N N . VAL A 1 87 ? -9.955 9.955 -42.658 1.00 300.69 ? 803 VAL A N 1 ATOM 698 C CA . VAL A 1 87 ? -8.992 10.355 -41.643 1.00 299.13 ? 803 VAL A CA 1 ATOM 699 C C . VAL A 1 87 ? -9.127 9.418 -40.452 1.00 299.91 ? 803 VAL A C 1 ATOM 700 O O . VAL A 1 87 ? -10.207 8.889 -40.170 1.00 303.78 ? 803 VAL A O 1 ATOM 701 C CB . VAL A 1 87 ? -9.176 11.824 -41.197 1.00 298.15 ? 803 VAL A CB 1 ATOM 702 C CG1 . VAL A 1 87 ? -8.750 12.777 -42.302 1.00 299.16 ? 803 VAL A CG1 1 ATOM 703 C CG2 . VAL A 1 87 ? -10.619 12.078 -40.789 1.00 300.38 ? 803 VAL A CG2 1 ATOM 704 N N . GLN A 1 88 ? -8.014 9.212 -39.753 1.00 302.75 ? 804 GLN A N 1 ATOM 705 C CA . GLN A 1 88 ? -7.977 8.375 -38.562 1.00 299.61 ? 804 GLN A CA 1 ATOM 706 C C . GLN A 1 88 ? -6.990 8.989 -37.583 1.00 299.74 ? 804 GLN A C 1 ATOM 707 O O . GLN A 1 88 ? -5.859 9.308 -37.963 1.00 302.46 ? 804 GLN A O 1 ATOM 708 C CB . GLN A 1 88 ? -7.575 6.937 -38.908 1.00 298.25 ? 804 GLN A CB 1 ATOM 709 C CG . GLN A 1 88 ? -7.857 5.935 -37.805 1.00 299.60 ? 804 GLN A CG 1 ATOM 710 C CD . GLN A 1 88 ? -7.603 4.503 -38.235 1.00 301.16 ? 804 GLN A CD 1 ATOM 711 O OE1 . GLN A 1 88 ? -6.927 4.252 -39.233 1.00 299.37 ? 804 GLN A OE1 1 ATOM 712 N NE2 . GLN A 1 88 ? -8.151 3.553 -37.484 1.00 302.60 ? 804 GLN A NE2 1 ATOM 713 N N . GLN A 1 89 ? -7.414 9.160 -36.334 1.00 304.05 ? 805 GLN A N 1 ATOM 714 C CA . GLN A 1 89 ? -6.627 9.885 -35.348 1.00 303.81 ? 805 GLN A CA 1 ATOM 715 C C . GLN A 1 89 ? -5.845 8.932 -34.454 1.00 306.16 ? 805 GLN A C 1 ATOM 716 O O . GLN A 1 89 ? -6.362 7.900 -34.016 1.00 308.12 ? 805 GLN A O 1 ATOM 717 C CB . GLN A 1 89 ? -7.513 10.785 -34.482 1.00 303.61 ? 805 GLN A CB 1 ATOM 718 C CG . GLN A 1 89 ? -6.716 11.692 -33.555 1.00 303.96 ? 805 GLN A CG 1 ATOM 719 C CD . GLN A 1 89 ? -7.585 12.458 -32.582 1.00 304.18 ? 805 GLN A CD 1 ATOM 720 O OE1 . GLN A 1 89 ? -8.138 13.506 -32.916 1.00 307.35 ? 805 GLN A OE1 1 ATOM 721 N NE2 . GLN A 1 89 ? -7.704 11.942 -31.365 1.00 304.01 ? 805 GLN A NE2 1 ATOM 722 N N . TRP A 1 90 ? -4.595 9.299 -34.188 1.00 327.69 ? 806 TRP A N 1 ATOM 723 C CA . TRP A 1 90 ? -3.715 8.603 -33.261 1.00 327.72 ? 806 TRP A CA 1 ATOM 724 C C . TRP A 1 90 ? -3.282 9.596 -32.192 1.00 329.84 ? 806 TRP A C 1 ATOM 725 O O . TRP A 1 90 ? -2.847 10.707 -32.517 1.00 330.41 ? 806 TRP A O 1 ATOM 726 C CB . TRP A 1 90 ? -2.508 8.019 -34.006 1.00 327.75 ? 806 TRP A CB 1 ATOM 727 C CG . TRP A 1 90 ? -1.408 7.488 -33.137 1.00 328.18 ? 806 TRP A CG 1 ATOM 728 C CD1 . TRP A 1 90 ? -0.187 8.061 -32.920 1.00 328.59 ? 806 TRP A CD1 1 ATOM 729 C CD2 . TRP A 1 90 ? -1.417 6.268 -32.385 1.00 328.08 ? 806 TRP A CD2 1 ATOM 730 N NE1 . TRP A 1 90 ? 0.561 7.276 -32.077 1.00 329.86 ? 806 TRP A NE1 1 ATOM 731 C CE2 . TRP A 1 90 ? -0.172 6.171 -31.733 1.00 327.60 ? 806 TRP A CE2 1 ATOM 732 C CE3 . TRP A 1 90 ? -2.358 5.252 -32.197 1.00 329.29 ? 806 TRP A CE3 1 ATOM 733 C CZ2 . TRP A 1 90 ? 0.156 5.098 -30.906 1.00 327.03 ? 806 TRP A CZ2 1 ATOM 734 C CZ3 . TRP A 1 90 ? -2.032 4.189 -31.375 1.00 328.96 ? 806 TRP A CZ3 1 ATOM 735 C CH2 . TRP A 1 90 ? -0.785 4.120 -30.739 1.00 327.76 ? 806 TRP A CH2 1 ATOM 736 N N . ARG A 1 91 ? -3.422 9.212 -30.923 1.00 325.12 ? 807 ARG A N 1 ATOM 737 C CA . ARG A 1 91 ? -3.168 10.128 -29.815 1.00 328.55 ? 807 ARG A CA 1 ATOM 738 C C . ARG A 1 91 ? -2.477 9.395 -28.676 1.00 329.56 ? 807 ARG A C 1 ATOM 739 O O . ARG A 1 91 ? -2.943 8.335 -28.247 1.00 336.33 ? 807 ARG A O 1 ATOM 740 C CB . ARG A 1 91 ? -4.470 10.761 -29.313 1.00 332.33 ? 807 ARG A CB 1 ATOM 741 C CG . ARG A 1 91 ? -4.262 12.052 -28.542 1.00 335.04 ? 807 ARG A CG 1 ATOM 742 C CD . ARG A 1 91 ? -5.478 12.397 -27.705 1.00 338.41 ? 807 ARG A CD 1 ATOM 743 N NE . ARG A 1 91 ? -5.658 11.447 -26.612 1.00 344.69 ? 807 ARG A NE 1 ATOM 744 C CZ . ARG A 1 91 ? -6.604 11.545 -25.684 1.00 348.45 ? 807 ARG A CZ 1 ATOM 745 N NH1 . ARG A 1 91 ? -6.690 10.634 -24.725 1.00 348.52 ? 807 ARG A NH1 1 ATOM 746 N NH2 . ARG A 1 91 ? -7.462 12.554 -25.715 1.00 349.54 ? 807 ARG A NH2 1 ATOM 747 N N . VAL A 1 92 ? -1.385 9.973 -28.178 1.00 341.30 ? 808 VAL A N 1 ATOM 748 C CA . VAL A 1 92 ? -0.576 9.383 -27.117 1.00 339.64 ? 808 VAL A CA 1 ATOM 749 C C . VAL A 1 92 ? -0.345 10.432 -26.039 1.00 339.13 ? 808 VAL A C 1 ATOM 750 O O . VAL A 1 92 ? 0.125 11.536 -26.334 1.00 341.11 ? 808 VAL A O 1 ATOM 751 C CB . VAL A 1 92 ? 0.772 8.859 -27.651 1.00 340.71 ? 808 VAL A CB 1 ATOM 752 C CG1 . VAL A 1 92 ? 1.589 8.248 -26.526 1.00 343.10 ? 808 VAL A CG1 1 ATOM 753 C CG2 . VAL A 1 92 ? 0.553 7.852 -28.764 1.00 340.10 ? 808 VAL A CG2 1 ATOM 754 N N . ARG A 1 93 ? -0.666 10.086 -24.793 1.00 340.06 ? 809 ARG A N 1 ATOM 755 C CA . ARG A 1 93 ? -0.457 10.955 -23.643 1.00 340.86 ? 809 ARG A CA 1 ATOM 756 C C . ARG A 1 93 ? 0.562 10.317 -22.711 1.00 345.59 ? 809 ARG A C 1 ATOM 757 O O . ARG A 1 93 ? 0.524 9.106 -22.478 1.00 347.48 ? 809 ARG A O 1 ATOM 758 C CB . ARG A 1 93 ? -1.777 11.217 -22.911 1.00 339.67 ? 809 ARG A CB 1 ATOM 759 C CG . ARG A 1 93 ? -2.795 11.954 -23.764 1.00 338.50 ? 809 ARG A CG 1 ATOM 760 C CD . ARG A 1 93 ? -4.055 12.281 -22.987 1.00 339.07 ? 809 ARG A CD 1 ATOM 761 N NE . ARG A 1 93 ? -4.733 13.449 -23.539 1.00 338.12 ? 809 ARG A NE 1 ATOM 762 C CZ . ARG A 1 93 ? -5.854 13.965 -23.046 1.00 339.77 ? 809 ARG A CZ 1 ATOM 763 N NH1 . ARG A 1 93 ? -6.432 13.411 -21.988 1.00 341.46 ? 809 ARG A NH1 1 ATOM 764 N NH2 . ARG A 1 93 ? -6.397 15.034 -23.611 1.00 341.03 ? 809 ARG A NH2 1 ATOM 765 N N . SER A 1 94 ? 1.468 11.135 -22.169 1.00 341.53 ? 810 SER A N 1 ATOM 766 C CA . SER A 1 94 ? 2.703 10.594 -21.607 1.00 345.56 ? 810 SER A CA 1 ATOM 767 C C . SER A 1 94 ? 3.165 11.219 -20.293 1.00 346.68 ? 810 SER A C 1 ATOM 768 O O . SER A 1 94 ? 3.813 10.519 -19.510 1.00 354.52 ? 810 SER A O 1 ATOM 769 C CB . SER A 1 94 ? 3.830 10.721 -22.639 1.00 347.04 ? 810 SER A CB 1 ATOM 770 O OG . SER A 1 94 ? 3.669 11.902 -23.412 1.00 351.80 ? 810 SER A OG 1 ATOM 771 N N . ASN A 1 95 ? 2.884 12.491 -20.015 1.00 346.40 ? 811 ASN A N 1 ATOM 772 C CA . ASN A 1 95 ? 3.469 13.131 -18.844 1.00 345.71 ? 811 ASN A CA 1 ATOM 773 C C . ASN A 1 95 ? 2.380 13.686 -17.931 1.00 341.93 ? 811 ASN A C 1 ATOM 774 O O . ASN A 1 95 ? 2.469 14.822 -17.457 1.00 339.48 ? 811 ASN A O 1 ATOM 775 C CB . ASN A 1 95 ? 4.436 14.235 -19.281 1.00 349.50 ? 811 ASN A CB 1 ATOM 776 C CG . ASN A 1 95 ? 5.359 14.692 -18.169 1.00 354.39 ? 811 ASN A CG 1 ATOM 777 O OD1 . ASN A 1 95 ? 5.623 13.965 -17.212 1.00 361.83 ? 811 ASN A OD1 1 ATOM 778 N ND2 . ASN A 1 95 ? 5.861 15.915 -18.294 1.00 357.16 ? 811 ASN A ND2 1 ATOM 779 N N . LEU A 1 96 ? 1.370 12.870 -17.636 1.00 353.41 ? 812 LEU A N 1 ATOM 780 C CA . LEU A 1 96 ? 0.097 13.378 -17.131 1.00 353.05 ? 812 LEU A CA 1 ATOM 781 C C . LEU A 1 96 ? 0.144 13.710 -15.645 1.00 352.38 ? 812 LEU A C 1 ATOM 782 O O . LEU A 1 96 ? 0.657 12.933 -14.833 1.00 356.66 ? 812 LEU A O 1 ATOM 783 C CB . LEU A 1 96 ? -1.008 12.356 -17.408 1.00 353.29 ? 812 LEU A CB 1 ATOM 784 C CG . LEU A 1 96 ? -1.202 12.041 -18.889 1.00 350.53 ? 812 LEU A CG 1 ATOM 785 C CD1 . LEU A 1 96 ? -2.150 10.871 -19.079 1.00 350.81 ? 812 LEU A CD1 1 ATOM 786 C CD2 . LEU A 1 96 ? -1.708 13.268 -19.625 1.00 350.86 ? 812 LEU A CD2 1 ATOM 787 N N . TYR A 1 97 ? -0.409 14.876 -15.299 1.00 360.25 ? 813 TYR A N 1 ATOM 788 C CA . TYR A 1 97 ? -0.664 15.287 -13.923 1.00 361.02 ? 813 TYR A CA 1 ATOM 789 C C . TYR A 1 97 ? -2.044 15.925 -13.854 1.00 362.34 ? 813 TYR A C 1 ATOM 790 O O . TYR A 1 97 ? -2.402 16.737 -14.716 1.00 358.73 ? 813 TYR A O 1 ATOM 791 C CB . TYR A 1 97 ? 0.376 16.291 -13.402 1.00 361.30 ? 813 TYR A CB 1 ATOM 792 C CG . TYR A 1 97 ? 1.806 15.798 -13.379 1.00 361.45 ? 813 TYR A CG 1 ATOM 793 C CD1 . TYR A 1 97 ? 2.332 15.177 -12.253 1.00 364.05 ? 813 TYR A CD1 1 ATOM 794 C CD2 . TYR A 1 97 ? 2.639 15.981 -14.474 1.00 363.74 ? 813 TYR A CD2 1 ATOM 795 C CE1 . TYR A 1 97 ? 3.645 14.737 -12.226 1.00 366.16 ? 813 TYR A CE1 1 ATOM 796 C CE2 . TYR A 1 97 ? 3.951 15.545 -14.457 1.00 367.01 ? 813 TYR A CE2 1 ATOM 797 C CZ . TYR A 1 97 ? 4.449 14.923 -13.330 1.00 368.75 ? 813 TYR A CZ 1 ATOM 798 O OH . TYR A 1 97 ? 5.754 14.487 -13.307 1.00 374.22 ? 813 TYR A OH 1 ATOM 799 N N . ARG A 1 98 ? -2.813 15.554 -12.832 1.00 360.19 ? 814 ARG A N 1 ATOM 800 C CA . ARG A 1 98 ? -4.114 16.154 -12.560 1.00 363.29 ? 814 ARG A CA 1 ATOM 801 C C . ARG A 1 98 ? -3.934 17.240 -11.507 1.00 362.92 ? 814 ARG A C 1 ATOM 802 O O . ARG A 1 98 ? -3.430 16.968 -10.412 1.00 365.07 ? 814 ARG A O 1 ATOM 803 C CB . ARG A 1 98 ? -5.111 15.097 -12.088 1.00 365.87 ? 814 ARG A CB 1 ATOM 804 C CG . ARG A 1 98 ? -6.482 15.632 -11.700 1.00 369.10 ? 814 ARG A CG 1 ATOM 805 C CD . ARG A 1 98 ? -7.233 16.220 -12.890 1.00 369.71 ? 814 ARG A CD 1 ATOM 806 N NE . ARG A 1 98 ? -7.152 15.382 -14.085 1.00 371.12 ? 814 ARG A NE 1 ATOM 807 C CZ . ARG A 1 98 ? -7.835 14.255 -14.265 1.00 372.42 ? 814 ARG A CZ 1 ATOM 808 N NH1 . ARG A 1 98 ? -8.653 13.809 -13.320 1.00 377.59 ? 814 ARG A NH1 1 ATOM 809 N NH2 . ARG A 1 98 ? -7.694 13.567 -15.390 1.00 371.56 ? 814 ARG A NH2 1 ATOM 810 N N . VAL A 1 99 ? -4.347 18.459 -11.836 1.00 356.58 ? 815 VAL A N 1 ATOM 811 C CA . VAL A 1 99 ? -4.034 19.639 -11.038 1.00 358.90 ? 815 VAL A CA 1 ATOM 812 C C . VAL A 1 99 ? -5.332 20.282 -10.572 1.00 362.93 ? 815 VAL A C 1 ATOM 813 O O . VAL A 1 99 ? -6.143 20.727 -11.394 1.00 359.85 ? 815 VAL A O 1 ATOM 814 C CB . VAL A 1 99 ? -3.183 20.646 -11.828 1.00 360.48 ? 815 VAL A CB 1 ATOM 815 C CG1 . VAL A 1 99 ? -2.909 21.881 -10.987 1.00 360.08 ? 815 VAL A CG1 1 ATOM 816 C CG2 . VAL A 1 99 ? -1.881 20.002 -12.279 1.00 362.46 ? 815 VAL A CG2 1 ATOM 817 N N . LYS A 1 100 ? -5.519 20.338 -9.256 1.00 360.05 ? 816 LYS A N 1 ATOM 818 C CA . LYS A 1 100 ? -6.595 21.085 -8.623 1.00 362.98 ? 816 LYS A CA 1 ATOM 819 C C . LYS A 1 100 ? -5.990 22.099 -7.661 1.00 365.30 ? 816 LYS A C 1 ATOM 820 O O . LYS A 1 100 ? -4.856 21.944 -7.202 1.00 367.47 ? 816 LYS A O 1 ATOM 821 C CB . LYS A 1 100 ? -7.559 20.157 -7.870 1.00 363.60 ? 816 LYS A CB 1 ATOM 822 C CG . LYS A 1 100 ? -8.048 18.970 -8.681 1.00 367.25 ? 816 LYS A CG 1 ATOM 823 C CD . LYS A 1 100 ? -8.893 18.037 -7.827 1.00 369.66 ? 816 LYS A CD 1 ATOM 824 C CE . LYS A 1 100 ? -8.636 16.584 -8.186 1.00 373.38 ? 816 LYS A CE 1 ATOM 825 N NZ . LYS A 1 100 ? -7.219 16.203 -7.929 1.00 375.33 ? 816 LYS A NZ 1 ATOM 826 N N . LEU A 1 101 ? -6.752 23.148 -7.356 1.00 352.47 ? 817 LEU A N 1 ATOM 827 C CA . LEU A 1 101 ? -6.294 24.197 -6.450 1.00 356.27 ? 817 LEU A CA 1 ATOM 828 C C . LEU A 1 101 ? -7.262 24.309 -5.279 1.00 361.32 ? 817 LEU A C 1 ATOM 829 O O . LEU A 1 101 ? -8.474 24.453 -5.479 1.00 366.08 ? 817 LEU A O 1 ATOM 830 C CB . LEU A 1 101 ? -6.135 25.538 -7.180 1.00 354.67 ? 817 LEU A CB 1 ATOM 831 C CG . LEU A 1 101 ? -7.276 26.541 -7.383 1.00 353.59 ? 817 LEU A CG 1 ATOM 832 C CD1 . LEU A 1 101 ? -6.742 27.811 -8.029 1.00 352.97 ? 817 LEU A CD1 1 ATOM 833 C CD2 . LEU A 1 101 ? -8.400 25.954 -8.216 1.00 355.10 ? 817 LEU A CD2 1 ATOM 834 N N . SER A 1 102 ? -6.719 24.224 -4.062 1.00 356.50 ? 818 SER A N 1 ATOM 835 C CA . SER A 1 102 ? -7.481 24.309 -2.820 1.00 361.72 ? 818 SER A CA 1 ATOM 836 C C . SER A 1 102 ? -6.543 24.172 -1.626 1.00 360.00 ? 818 SER A C 1 ATOM 837 O O . SER A 1 102 ? -5.835 23.168 -1.508 1.00 359.67 ? 818 SER A O 1 ATOM 838 C CB . SER A 1 102 ? -8.563 23.227 -2.756 1.00 367.12 ? 818 SER A CB 1 ATOM 839 O OG . SER A 1 102 ? -9.333 23.345 -1.572 1.00 377.17 ? 818 SER A OG 1 ATOM 840 N N . THR A 1 103 ? -6.518 25.165 -0.740 1.00 350.47 ? 819 THR A N 1 ATOM 841 C CA . THR A 1 103 ? -7.304 26.387 -0.884 1.00 348.82 ? 819 THR A CA 1 ATOM 842 C C . THR A 1 103 ? -6.355 27.583 -0.926 1.00 347.72 ? 819 THR A C 1 ATOM 843 O O . THR A 1 103 ? -5.307 27.573 -0.279 1.00 354.07 ? 819 THR A O 1 ATOM 844 C CB . THR A 1 103 ? -8.324 26.545 0.264 1.00 348.61 ? 819 THR A CB 1 ATOM 845 O OG1 . THR A 1 103 ? -9.088 27.741 0.075 1.00 345.19 ? 819 THR A OG1 1 ATOM 846 C CG2 . THR A 1 103 ? -7.617 26.600 1.612 1.00 348.81 ? 819 THR A CG2 1 ATOM 847 N N . ILE A 1 104 ? -6.707 28.608 -1.700 1.00 347.99 ? 820 ILE A N 1 ATOM 848 C CA . ILE A 1 104 ? -5.810 29.726 -1.969 1.00 346.24 ? 820 ILE A CA 1 ATOM 849 C C . ILE A 1 104 ? -6.536 31.036 -1.698 1.00 342.30 ? 820 ILE A C 1 ATOM 850 O O . ILE A 1 104 ? -7.704 31.199 -2.065 1.00 341.44 ? 820 ILE A O 1 ATOM 851 C CB . ILE A 1 104 ? -5.282 29.689 -3.419 1.00 348.44 ? 820 ILE A CB 1 ATOM 852 C CG1 . ILE A 1 104 ? -4.770 28.289 -3.761 1.00 353.63 ? 820 ILE A CG1 1 ATOM 853 C CG2 . ILE A 1 104 ? -4.176 30.715 -3.615 1.00 346.03 ? 820 ILE A CG2 1 ATOM 854 C CD1 . ILE A 1 104 ? -4.180 28.172 -5.138 1.00 357.72 ? 820 ILE A CD1 1 ATOM 855 N N . THR A 1 105 ? -5.837 31.968 -1.055 1.00 351.43 ? 821 THR A N 1 ATOM 856 C CA . THR A 1 105 ? -6.356 33.307 -0.837 1.00 348.04 ? 821 THR A CA 1 ATOM 857 C C . THR A 1 105 ? -6.272 34.123 -2.124 1.00 345.70 ? 821 THR A C 1 ATOM 858 O O . THR A 1 105 ? -5.483 33.833 -3.027 1.00 346.80 ? 821 THR A O 1 ATOM 859 C CB . THR A 1 105 ? -5.586 34.011 0.282 1.00 346.51 ? 821 THR A CB 1 ATOM 860 O OG1 . THR A 1 105 ? -4.210 34.148 -0.094 1.00 341.20 ? 821 THR A OG1 1 ATOM 861 C CG2 . THR A 1 105 ? -5.674 33.211 1.574 1.00 346.03 ? 821 THR A CG2 1 ATOM 862 N N . LEU A 1 106 ? -7.099 35.163 -2.195 1.00 343.36 ? 822 LEU A N 1 ATOM 863 C CA . LEU A 1 106 ? -7.206 35.955 -3.411 1.00 343.64 ? 822 LEU A CA 1 ATOM 864 C C . LEU A 1 106 ? -5.987 36.856 -3.585 1.00 341.57 ? 822 LEU A C 1 ATOM 865 O O . LEU A 1 106 ? -5.242 37.134 -2.643 1.00 342.51 ? 822 LEU A O 1 ATOM 866 C CB . LEU A 1 106 ? -8.489 36.790 -3.397 1.00 346.32 ? 822 LEU A CB 1 ATOM 867 C CG . LEU A 1 106 ? -9.796 36.103 -3.810 1.00 348.09 ? 822 LEU A CG 1 ATOM 868 C CD1 . LEU A 1 106 ? -10.192 34.987 -2.850 1.00 348.11 ? 822 LEU A CD1 1 ATOM 869 C CD2 . LEU A 1 106 ? -10.920 37.123 -3.933 1.00 347.82 ? 822 LEU A CD2 1 ATOM 870 N N . ALA A 1 107 ? -5.791 37.313 -4.819 1.00 352.60 ? 823 ALA A N 1 ATOM 871 C CA . ALA A 1 107 ? -4.643 38.144 -5.142 1.00 355.91 ? 823 ALA A CA 1 ATOM 872 C C . ALA A 1 107 ? -4.825 39.560 -4.605 1.00 359.40 ? 823 ALA A C 1 ATOM 873 O O . ALA A 1 107 ? -5.937 40.007 -4.312 1.00 361.56 ? 823 ALA A O 1 ATOM 874 C CB . ALA A 1 107 ? -4.414 38.184 -6.653 1.00 357.04 ? 823 ALA A CB 1 ATOM 875 N N . ALA A 1 108 ? -3.702 40.271 -4.485 1.00 366.70 ? 824 ALA A N 1 ATOM 876 C CA . ALA A 1 108 ? -3.736 41.643 -3.991 1.00 368.75 ? 824 ALA A CA 1 ATOM 877 C C . ALA A 1 108 ? -4.400 42.574 -4.999 1.00 367.80 ? 824 ALA A C 1 ATOM 878 O O . ALA A 1 108 ? -5.356 43.285 -4.671 1.00 365.73 ? 824 ALA A O 1 ATOM 879 C CB . ALA A 1 108 ? -2.320 42.118 -3.663 1.00 370.57 ? 824 ALA A CB 1 ATOM 880 N N . GLY A 1 109 ? -3.901 42.585 -6.236 1.00 373.25 ? 825 GLY A N 1 ATOM 881 C CA . GLY A 1 109 ? -4.469 43.460 -7.248 1.00 372.31 ? 825 GLY A CA 1 ATOM 882 C C . GLY A 1 109 ? -5.886 43.093 -7.633 1.00 372.18 ? 825 GLY A C 1 ATOM 883 O O . GLY A 1 109 ? -6.659 43.954 -8.065 1.00 369.89 ? 825 GLY A O 1 ATOM 884 N N . PHE A 1 110 ? -6.249 41.817 -7.491 1.00 370.41 ? 826 PHE A N 1 ATOM 885 C CA . PHE A 1 110 ? -7.616 41.399 -7.783 1.00 372.91 ? 826 PHE A CA 1 ATOM 886 C C . PHE A 1 110 ? -8.591 41.983 -6.772 1.00 375.07 ? 826 PHE A C 1 ATOM 887 O O . PHE A 1 110 ? -9.657 42.488 -7.142 1.00 377.95 ? 826 PHE A O 1 ATOM 888 C CB . PHE A 1 110 ? -7.708 39.871 -7.804 1.00 372.77 ? 826 PHE A CB 1 ATOM 889 C CG . PHE A 1 110 ? -9.083 39.347 -8.122 1.00 370.09 ? 826 PHE A CG 1 ATOM 890 C CD1 . PHE A 1 110 ? -9.503 39.217 -9.436 1.00 366.72 ? 826 PHE A CD1 1 ATOM 891 C CD2 . PHE A 1 110 ? -9.952 38.976 -7.107 1.00 369.81 ? 826 PHE A CD2 1 ATOM 892 C CE1 . PHE A 1 110 ? -10.765 38.732 -9.732 1.00 366.09 ? 826 PHE A CE1 1 ATOM 893 C CE2 . PHE A 1 110 ? -11.215 38.491 -7.397 1.00 367.60 ? 826 PHE A CE2 1 ATOM 894 C CZ . PHE A 1 110 ? -11.622 38.369 -8.712 1.00 364.96 ? 826 PHE A CZ 1 ATOM 895 N N . THR A 1 111 ? -8.239 41.931 -5.486 1.00 372.91 ? 827 THR A N 1 ATOM 896 C CA . THR A 1 111 ? -9.133 42.439 -4.451 1.00 371.77 ? 827 THR A CA 1 ATOM 897 C C . THR A 1 111 ? -9.193 43.961 -4.454 1.00 370.83 ? 827 THR A C 1 ATOM 898 O O . THR A 1 111 ? -10.204 44.539 -4.041 1.00 368.11 ? 827 THR A O 1 ATOM 899 C CB . THR A 1 111 ? -8.694 41.929 -3.077 1.00 370.98 ? 827 THR A CB 1 ATOM 900 O OG1 . THR A 1 111 ? -8.304 40.554 -3.182 1.00 371.25 ? 827 THR A OG1 1 ATOM 901 C CG2 . THR A 1 111 ? -9.834 42.048 -2.076 1.00 372.29 ? 827 THR A CG2 1 ATOM 902 N N . ASN A 1 112 ? -8.129 44.623 -4.911 1.00 367.90 ? 828 ASN A N 1 ATOM 903 C CA . ASN A 1 112 ? -8.134 46.081 -4.985 1.00 371.15 ? 828 ASN A CA 1 ATOM 904 C C . ASN A 1 112 ? -9.201 46.575 -5.953 1.00 371.66 ? 828 ASN A C 1 ATOM 905 O O . ASN A 1 112 ? -10.038 47.415 -5.599 1.00 374.86 ? 828 ASN A O 1 ATOM 906 C CB . ASN A 1 112 ? -6.753 46.597 -5.402 1.00 373.57 ? 828 ASN A CB 1 ATOM 907 C CG . ASN A 1 112 ? -5.736 46.529 -4.277 1.00 374.31 ? 828 ASN A CG 1 ATOM 908 O OD1 . ASN A 1 112 ? -4.623 46.039 -4.463 1.00 374.04 ? 828 ASN A OD1 1 ATOM 909 N ND2 . ASN A 1 112 ? -6.111 47.032 -3.105 1.00 374.48 ? 828 ASN A ND2 1 ATOM 910 N N . VAL A 1 113 ? -9.188 46.061 -7.185 1.00 367.88 ? 829 VAL A N 1 ATOM 911 C CA . VAL A 1 113 ? -10.198 46.463 -8.158 1.00 366.61 ? 829 VAL A CA 1 ATOM 912 C C . VAL A 1 113 ? -11.555 45.872 -7.801 1.00 361.65 ? 829 VAL A C 1 ATOM 913 O O . VAL A 1 113 ? -12.598 46.416 -8.186 1.00 361.87 ? 829 VAL A O 1 ATOM 914 C CB . VAL A 1 113 ? -9.762 46.066 -9.581 1.00 370.55 ? 829 VAL A CB 1 ATOM 915 C CG1 . VAL A 1 113 ? -8.459 46.766 -9.951 1.00 372.80 ? 829 VAL A CG1 1 ATOM 916 C CG2 . VAL A 1 113 ? -9.615 44.558 -9.696 1.00 371.63 ? 829 VAL A CG2 1 ATOM 917 N N . LEU A 1 114 ? -11.572 44.759 -7.062 1.00 362.38 ? 830 LEU A N 1 ATOM 918 C CA . LEU A 1 114 ? -12.837 44.193 -6.605 1.00 364.06 ? 830 LEU A CA 1 ATOM 919 C C . LEU A 1 114 ? -13.461 45.044 -5.508 1.00 367.09 ? 830 LEU A C 1 ATOM 920 O O . LEU A 1 114 ? -14.689 45.051 -5.353 1.00 365.21 ? 830 LEU A O 1 ATOM 921 C CB . LEU A 1 114 ? -12.624 42.757 -6.117 1.00 364.22 ? 830 LEU A CB 1 ATOM 922 C CG . LEU A 1 114 ? -13.852 41.862 -5.941 1.00 363.90 ? 830 LEU A CG 1 ATOM 923 C CD1 . LEU A 1 114 ? -14.454 41.506 -7.292 1.00 362.79 ? 830 LEU A CD1 1 ATOM 924 C CD2 . LEU A 1 114 ? -13.502 40.604 -5.157 1.00 363.82 ? 830 LEU A CD2 1 ATOM 925 N N . LYS A 1 115 ? -12.638 45.769 -4.746 1.00 362.52 ? 831 LYS A N 1 ATOM 926 C CA . LYS A 1 115 ? -13.151 46.634 -3.688 1.00 365.89 ? 831 LYS A CA 1 ATOM 927 C C . LYS A 1 115 ? -13.768 47.912 -4.245 1.00 365.46 ? 831 LYS A C 1 ATOM 928 O O . LYS A 1 115 ? -14.757 48.411 -3.702 1.00 364.70 ? 831 LYS A O 1 ATOM 929 C CB . LYS A 1 115 ? -12.038 46.993 -2.701 1.00 367.35 ? 831 LYS A CB 1 ATOM 930 C CG . LYS A 1 115 ? -11.759 45.952 -1.628 1.00 368.10 ? 831 LYS A CG 1 ATOM 931 C CD . LYS A 1 115 ? -11.092 46.596 -0.418 1.00 368.74 ? 831 LYS A CD 1 ATOM 932 C CE . LYS A 1 115 ? -10.484 45.563 0.516 1.00 368.37 ? 831 LYS A CE 1 ATOM 933 N NZ . LYS A 1 115 ? -9.204 45.025 -0.020 1.00 367.98 ? 831 LYS A NZ 1 ATOM 934 N N . ILE A 1 116 ? -13.192 48.465 -5.313 1.00 359.38 ? 832 ILE A N 1 ATOM 935 C CA . ILE A 1 116 ? -13.689 49.741 -5.817 1.00 362.16 ? 832 ILE A CA 1 ATOM 936 C C . ILE A 1 116 ? -14.896 49.541 -6.729 1.00 367.66 ? 832 ILE A C 1 ATOM 937 O O . ILE A 1 116 ? -15.779 50.403 -6.791 1.00 371.47 ? 832 ILE A O 1 ATOM 938 C CB . ILE A 1 116 ? -12.565 50.521 -6.527 1.00 358.98 ? 832 ILE A CB 1 ATOM 939 C CG1 . ILE A 1 116 ? -12.108 49.805 -7.802 1.00 358.02 ? 832 ILE A CG1 1 ATOM 940 C CG2 . ILE A 1 116 ? -11.386 50.724 -5.588 1.00 358.76 ? 832 ILE A CG2 1 ATOM 941 C CD1 . ILE A 1 116 ? -11.101 50.592 -8.621 1.00 358.13 ? 832 ILE A CD1 1 ATOM 942 N N . LEU A 1 117 ? -14.964 48.412 -7.434 1.00 360.97 ? 833 LEU A N 1 ATOM 943 C CA . LEU A 1 117 ? -16.072 48.161 -8.346 1.00 363.65 ? 833 LEU A CA 1 ATOM 944 C C . LEU A 1 117 ? -17.322 47.662 -7.638 1.00 368.57 ? 833 LEU A C 1 ATOM 945 O O . LEU A 1 117 ? -18.412 47.744 -8.213 1.00 370.96 ? 833 LEU A O 1 ATOM 946 C CB . LEU A 1 117 ? -15.661 47.148 -9.420 1.00 362.44 ? 833 LEU A CB 1 ATOM 947 C CG . LEU A 1 117 ? -15.204 47.671 -10.785 1.00 363.61 ? 833 LEU A CG 1 ATOM 948 C CD1 . LEU A 1 117 ? -13.933 48.494 -10.663 1.00 364.99 ? 833 LEU A CD1 1 ATOM 949 C CD2 . LEU A 1 117 ? -15.009 46.525 -11.770 1.00 363.22 ? 833 LEU A CD2 1 ATOM 950 N N . THR A 1 118 ? -17.196 47.152 -6.410 1.00 350.00 ? 834 THR A N 1 ATOM 951 C CA . THR A 1 118 ? -18.340 46.518 -5.761 1.00 356.32 ? 834 THR A CA 1 ATOM 952 C C . THR A 1 118 ? -19.443 47.528 -5.462 1.00 362.37 ? 834 THR A C 1 ATOM 953 O O . THR A 1 118 ? -20.633 47.198 -5.537 1.00 360.06 ? 834 THR A O 1 ATOM 954 C CB . THR A 1 118 ? -17.896 45.791 -4.487 1.00 356.77 ? 834 THR A CB 1 ATOM 955 O OG1 . THR A 1 118 ? -18.999 45.045 -3.953 1.00 355.64 ? 834 THR A OG1 1 ATOM 956 C CG2 . THR A 1 118 ? -17.402 46.771 -3.434 1.00 355.18 ? 834 THR A CG2 1 ATOM 957 N N . LYS A 1 119 ? -19.070 48.767 -5.140 1.00 366.55 ? 835 LYS A N 1 ATOM 958 C CA . LYS A 1 119 ? -20.062 49.817 -4.933 1.00 366.00 ? 835 LYS A CA 1 ATOM 959 C C . LYS A 1 119 ? -20.481 50.446 -6.255 1.00 366.70 ? 835 LYS A C 1 ATOM 960 O O . LYS A 1 119 ? -21.662 50.758 -6.454 1.00 366.90 ? 835 LYS A O 1 ATOM 961 C CB . LYS A 1 119 ? -19.503 50.890 -3.998 1.00 362.06 ? 835 LYS A CB 1 ATOM 962 C CG . LYS A 1 119 ? -19.117 50.381 -2.622 1.00 357.64 ? 835 LYS A CG 1 ATOM 963 C CD . LYS A 1 119 ? -18.001 51.218 -2.010 1.00 352.68 ? 835 LYS A CD 1 ATOM 964 C CE . LYS A 1 119 ? -16.692 51.028 -2.763 1.00 348.39 ? 835 LYS A CE 1 ATOM 965 N NZ . LYS A 1 119 ? -15.525 51.568 -2.009 1.00 346.41 ? 835 LYS A NZ 1 ATOM 966 N N . GLU A 1 120 ? -19.528 50.631 -7.165 1.00 368.05 ? 836 GLU A N 1 ATOM 967 C CA . GLU A 1 120 ? -19.747 51.312 -8.440 1.00 362.59 ? 836 GLU A CA 1 ATOM 968 C C . GLU A 1 120 ? -20.479 50.369 -9.394 1.00 352.55 ? 836 GLU A C 1 ATOM 969 O O . GLU A 1 120 ? -19.867 49.650 -10.186 1.00 341.86 ? 836 GLU A O 1 ATOM 970 C CB . GLU A 1 120 ? -18.420 51.780 -9.023 1.00 364.14 ? 836 GLU A CB 1 ATOM 971 C CG . GLU A 1 120 ? -18.548 52.614 -10.283 1.00 364.72 ? 836 GLU A CG 1 ATOM 972 C CD . GLU A 1 120 ? -19.029 54.022 -10.002 1.00 365.45 ? 836 GLU A CD 1 ATOM 973 O OE1 . GLU A 1 120 ? -18.457 54.681 -9.110 1.00 367.67 ? 836 GLU A OE1 1 ATOM 974 O OE2 . GLU A 1 120 ? -19.987 54.467 -10.666 1.00 364.56 ? 836 GLU A OE2 1 ATOM 975 N N . SER A 1 121 ? -21.808 50.377 -9.329 1.00 356.96 ? 837 SER A N 1 ATOM 976 C CA . SER A 1 121 ? -22.621 49.570 -10.237 1.00 349.85 ? 837 SER A CA 1 ATOM 977 C C . SER A 1 121 ? -22.655 50.245 -11.603 1.00 349.54 ? 837 SER A C 1 ATOM 978 O O . SER A 1 121 ? -23.426 51.181 -11.826 1.00 353.86 ? 837 SER A O 1 ATOM 979 C CB . SER A 1 121 ? -24.028 49.377 -9.678 1.00 342.75 ? 837 SER A CB 1 ATOM 980 O OG . SER A 1 121 ? -24.007 48.686 -8.443 1.00 336.10 ? 837 SER A OG 1 ATOM 981 N N . SER A 1 122 ? -21.827 49.760 -12.525 1.00 345.31 ? 838 SER A N 1 ATOM 982 C CA . SER A 1 122 ? -21.697 50.335 -13.859 1.00 345.07 ? 838 SER A CA 1 ATOM 983 C C . SER A 1 122 ? -21.487 49.221 -14.874 1.00 349.88 ? 838 SER A C 1 ATOM 984 O O . SER A 1 122 ? -20.809 48.231 -14.588 1.00 356.53 ? 838 SER A O 1 ATOM 985 C CB . SER A 1 122 ? -20.531 51.332 -13.921 1.00 340.57 ? 838 SER A CB 1 ATOM 986 O OG . SER A 1 122 ? -20.319 51.792 -15.244 1.00 336.50 ? 838 SER A OG 1 ATOM 987 N N . ARG A 1 123 ? -22.066 49.391 -16.064 1.00 347.73 ? 839 ARG A N 1 ATOM 988 C CA . ARG A 1 123 ? -22.019 48.344 -17.084 1.00 346.28 ? 839 ARG A CA 1 ATOM 989 C C . ARG A 1 123 ? -20.726 48.396 -17.888 1.00 346.14 ? 839 ARG A C 1 ATOM 990 O O . ARG A 1 123 ? -20.030 47.383 -18.017 1.00 347.71 ? 839 ARG A O 1 ATOM 991 C CB . ARG A 1 123 ? -23.236 48.456 -18.005 1.00 345.69 ? 839 ARG A CB 1 ATOM 992 C CG . ARG A 1 123 ? -23.179 47.567 -19.241 1.00 342.43 ? 839 ARG A CG 1 ATOM 993 C CD . ARG A 1 123 ? -22.945 46.102 -18.890 1.00 340.22 ? 839 ARG A CD 1 ATOM 994 N NE . ARG A 1 123 ? -24.007 45.544 -18.058 1.00 338.46 ? 839 ARG A NE 1 ATOM 995 C CZ . ARG A 1 123 ? -25.099 44.958 -18.536 1.00 340.65 ? 839 ARG A CZ 1 ATOM 996 N NH1 . ARG A 1 123 ? -25.278 44.857 -19.846 1.00 340.99 ? 839 ARG A NH1 1 ATOM 997 N NH2 . ARG A 1 123 ? -26.013 44.473 -17.707 1.00 341.56 ? 839 ARG A NH2 1 ATOM 998 N N . GLU A 1 124 ? -20.399 49.561 -18.454 1.00 344.26 ? 840 GLU A N 1 ATOM 999 C CA . GLU A 1 124 ? -19.145 49.698 -19.185 1.00 342.58 ? 840 GLU A CA 1 ATOM 1000 C C . GLU A 1 124 ? -17.949 49.367 -18.303 1.00 338.43 ? 840 GLU A C 1 ATOM 1001 O O . GLU A 1 124 ? -16.911 48.919 -18.799 1.00 332.10 ? 840 GLU A O 1 ATOM 1002 C CB . GLU A 1 124 ? -19.005 51.118 -19.738 1.00 346.57 ? 840 GLU A CB 1 ATOM 1003 C CG . GLU A 1 124 ? -20.138 51.555 -20.657 1.00 349.80 ? 840 GLU A CG 1 ATOM 1004 C CD . GLU A 1 124 ? -20.065 50.921 -22.035 1.00 352.35 ? 840 GLU A CD 1 ATOM 1005 O OE1 . GLU A 1 124 ? -19.034 50.290 -22.348 1.00 355.89 ? 840 GLU A OE1 1 ATOM 1006 O OE2 . GLU A 1 124 ? -21.037 51.058 -22.808 1.00 351.82 ? 840 GLU A OE2 1 ATOM 1007 N N . GLU A 1 125 ? -18.079 49.580 -16.997 1.00 347.64 ? 841 GLU A N 1 ATOM 1008 C CA . GLU A 1 125 ? -16.980 49.304 -16.084 1.00 347.79 ? 841 GLU A CA 1 ATOM 1009 C C . GLU A 1 125 ? -16.855 47.809 -15.831 1.00 343.79 ? 841 GLU A C 1 ATOM 1010 O O . GLU A 1 125 ? -15.748 47.263 -15.794 1.00 347.55 ? 841 GLU A O 1 ATOM 1011 C CB . GLU A 1 125 ? -17.205 50.068 -14.778 1.00 353.10 ? 841 GLU A CB 1 ATOM 1012 C CG . GLU A 1 125 ? -16.008 50.197 -13.860 1.00 358.20 ? 841 GLU A CG 1 ATOM 1013 C CD . GLU A 1 125 ? -16.268 51.200 -12.744 1.00 360.98 ? 841 GLU A CD 1 ATOM 1014 O OE1 . GLU A 1 125 ? -16.922 52.233 -13.010 1.00 360.12 ? 841 GLU A OE1 1 ATOM 1015 O OE2 . GLU A 1 125 ? -15.832 50.955 -11.600 1.00 363.59 ? 841 GLU A OE2 1 ATOM 1016 N N . LEU A 1 126 ? -17.989 47.127 -15.667 1.00 344.21 ? 842 LEU A N 1 ATOM 1017 C CA . LEU A 1 126 ? -17.950 45.704 -15.375 1.00 342.69 ? 842 LEU A CA 1 ATOM 1018 C C . LEU A 1 126 ? -17.459 44.907 -16.573 1.00 344.32 ? 842 LEU A C 1 ATOM 1019 O O . LEU A 1 126 ? -16.923 43.803 -16.412 1.00 342.44 ? 842 LEU A O 1 ATOM 1020 C CB . LEU A 1 126 ? -19.331 45.215 -14.931 1.00 338.74 ? 842 LEU A CB 1 ATOM 1021 C CG . LEU A 1 126 ? -19.759 45.460 -13.481 1.00 335.85 ? 842 LEU A CG 1 ATOM 1022 C CD1 . LEU A 1 126 ? -21.253 45.205 -13.315 1.00 334.28 ? 842 LEU A CD1 1 ATOM 1023 C CD2 . LEU A 1 126 ? -18.964 44.577 -12.539 1.00 336.59 ? 842 LEU A CD2 1 ATOM 1024 N N . LEU A 1 127 ? -17.615 45.454 -17.777 1.00 338.65 ? 843 LEU A N 1 ATOM 1025 C CA . LEU A 1 127 ? -17.130 44.766 -18.963 1.00 335.92 ? 843 LEU A CA 1 ATOM 1026 C C . LEU A 1 127 ? -15.615 44.875 -19.079 1.00 336.27 ? 843 LEU A C 1 ATOM 1027 O O . LEU A 1 127 ? -14.942 43.904 -19.454 1.00 342.21 ? 843 LEU A O 1 ATOM 1028 C CB . LEU A 1 127 ? -17.815 45.323 -20.211 1.00 334.03 ? 843 LEU A CB 1 ATOM 1029 C CG . LEU A 1 127 ? -19.318 45.074 -20.370 1.00 332.19 ? 843 LEU A CG 1 ATOM 1030 C CD1 . LEU A 1 127 ? -19.818 45.746 -21.639 1.00 331.28 ? 843 LEU A CD1 1 ATOM 1031 C CD2 . LEU A 1 127 ? -19.622 43.585 -20.397 1.00 331.13 ? 843 LEU A CD2 1 ATOM 1032 N N . SER A 1 128 ? -15.059 46.041 -18.745 1.00 336.92 ? 844 SER A N 1 ATOM 1033 C CA . SER A 1 128 ? -13.608 46.199 -18.745 1.00 336.83 ? 844 SER A CA 1 ATOM 1034 C C . SER A 1 128 ? -12.948 45.293 -17.716 1.00 330.98 ? 844 SER A C 1 ATOM 1035 O O . SER A 1 128 ? -11.784 44.910 -17.880 1.00 330.92 ? 844 SER A O 1 ATOM 1036 C CB . SER A 1 128 ? -13.235 47.661 -18.490 1.00 340.33 ? 844 SER A CB 1 ATOM 1037 O OG . SER A 1 128 ? -13.545 48.467 -19.613 1.00 348.70 ? 844 SER A OG 1 ATOM 1038 N N . PHE A 1 129 ? -13.671 44.943 -16.653 1.00 345.91 ? 845 PHE A N 1 ATOM 1039 C CA . PHE A 1 129 ? -13.170 43.962 -15.696 1.00 346.83 ? 845 PHE A CA 1 ATOM 1040 C C . PHE A 1 129 ? -13.062 42.586 -16.340 1.00 343.65 ? 845 PHE A C 1 ATOM 1041 O O . PHE A 1 129 ? -12.052 41.891 -16.180 1.00 345.78 ? 845 PHE A O 1 ATOM 1042 C CB . PHE A 1 129 ? -14.086 43.919 -14.471 1.00 348.27 ? 845 PHE A CB 1 ATOM 1043 C CG . PHE A 1 129 ? -13.665 42.922 -13.425 1.00 349.03 ? 845 PHE A CG 1 ATOM 1044 C CD1 . PHE A 1 129 ? -14.099 41.607 -13.483 1.00 348.53 ? 845 PHE A CD1 1 ATOM 1045 C CD2 . PHE A 1 129 ? -12.852 43.307 -12.372 1.00 350.92 ? 845 PHE A CD2 1 ATOM 1046 C CE1 . PHE A 1 129 ? -13.719 40.692 -12.521 1.00 350.69 ? 845 PHE A CE1 1 ATOM 1047 C CE2 . PHE A 1 129 ? -12.470 42.396 -11.404 1.00 352.34 ? 845 PHE A CE2 1 ATOM 1048 C CZ . PHE A 1 129 ? -12.904 41.086 -11.479 1.00 351.60 ? 845 PHE A CZ 1 ATOM 1049 N N . ILE A 1 130 ? -14.097 42.180 -17.078 1.00 343.03 ? 846 ILE A N 1 ATOM 1050 C CA . ILE A 1 130 ? -14.116 40.848 -17.673 1.00 337.98 ? 846 ILE A CA 1 ATOM 1051 C C . ILE A 1 130 ? -13.076 40.737 -18.781 1.00 334.57 ? 846 ILE A C 1 ATOM 1052 O O . ILE A 1 130 ? -12.461 39.681 -18.969 1.00 331.17 ? 846 ILE A O 1 ATOM 1053 C CB . ILE A 1 130 ? -15.534 40.517 -18.175 1.00 336.66 ? 846 ILE A CB 1 ATOM 1054 C CG1 . ILE A 1 130 ? -16.514 40.484 -16.998 1.00 339.10 ? 846 ILE A CG1 1 ATOM 1055 C CG2 . ILE A 1 130 ? -15.550 39.191 -18.919 1.00 335.77 ? 846 ILE A CG2 1 ATOM 1056 C CD1 . ILE A 1 130 ? -17.962 40.345 -17.412 1.00 339.53 ? 846 ILE A CD1 1 ATOM 1057 N N . GLN A 1 131 ? -12.855 41.823 -19.527 1.00 330.12 ? 847 GLN A N 1 ATOM 1058 C CA . GLN A 1 131 ? -11.786 41.836 -20.523 1.00 336.19 ? 847 GLN A CA 1 ATOM 1059 C C . GLN A 1 131 ? -10.444 41.497 -19.890 1.00 337.79 ? 847 GLN A C 1 ATOM 1060 O O . GLN A 1 131 ? -9.650 40.737 -20.456 1.00 339.81 ? 847 GLN A O 1 ATOM 1061 C CB . GLN A 1 131 ? -11.703 43.207 -21.199 1.00 342.08 ? 847 GLN A CB 1 ATOM 1062 C CG . GLN A 1 131 ? -12.818 43.529 -22.173 1.00 348.73 ? 847 GLN A CG 1 ATOM 1063 C CD . GLN A 1 131 ? -12.556 44.824 -22.923 1.00 354.10 ? 847 GLN A CD 1 ATOM 1064 O OE1 . GLN A 1 131 ? -11.409 45.248 -23.069 1.00 353.31 ? 847 GLN A OE1 1 ATOM 1065 N NE2 . GLN A 1 131 ? -13.620 45.463 -23.395 1.00 357.25 ? 847 GLN A NE2 1 ATOM 1066 N N . HIS A 1 132 ? -10.184 42.047 -18.706 1.00 344.96 ? 848 HIS A N 1 ATOM 1067 C CA . HIS A 1 132 ? -8.881 41.903 -18.073 1.00 345.98 ? 848 HIS A CA 1 ATOM 1068 C C . HIS A 1 132 ? -8.779 40.607 -17.279 1.00 340.79 ? 848 HIS A C 1 ATOM 1069 O O . HIS A 1 132 ? -7.785 39.881 -17.387 1.00 341.75 ? 848 HIS A O 1 ATOM 1070 C CB . HIS A 1 132 ? -8.614 43.109 -17.171 1.00 349.28 ? 848 HIS A CB 1 ATOM 1071 C CG . HIS A 1 132 ? -7.205 43.199 -16.679 1.00 353.45 ? 848 HIS A CG 1 ATOM 1072 N ND1 . HIS A 1 132 ? -6.771 42.554 -15.542 1.00 354.02 ? 848 HIS A ND1 1 ATOM 1073 C CD2 . HIS A 1 132 ? -6.131 43.862 -17.170 1.00 354.39 ? 848 HIS A CD2 1 ATOM 1074 C CE1 . HIS A 1 132 ? -5.490 42.814 -15.354 1.00 355.38 ? 848 HIS A CE1 1 ATOM 1075 N NE2 . HIS A 1 132 ? -5.078 43.606 -16.328 1.00 356.09 ? 848 HIS A NE2 1 ATOM 1076 N N . TYR A 1 133 ? -9.797 40.297 -16.479 1.00 344.27 ? 849 TYR A N 1 ATOM 1077 C CA . TYR A 1 133 ? -9.736 39.165 -15.564 1.00 344.74 ? 849 TYR A CA 1 ATOM 1078 C C . TYR A 1 133 ? -10.483 37.932 -16.053 1.00 340.60 ? 849 TYR A C 1 ATOM 1079 O O . TYR A 1 133 ? -10.425 36.893 -15.388 1.00 337.58 ? 849 TYR A O 1 ATOM 1080 C CB . TYR A 1 133 ? -10.282 39.568 -14.188 1.00 350.68 ? 849 TYR A CB 1 ATOM 1081 C CG . TYR A 1 133 ? -9.362 40.487 -13.422 1.00 357.34 ? 849 TYR A CG 1 ATOM 1082 C CD1 . TYR A 1 133 ? -8.295 39.980 -12.692 1.00 359.91 ? 849 TYR A CD1 1 ATOM 1083 C CD2 . TYR A 1 133 ? -9.558 41.862 -13.429 1.00 362.33 ? 849 TYR A CD2 1 ATOM 1084 C CE1 . TYR A 1 133 ? -7.449 40.816 -11.989 1.00 363.74 ? 849 TYR A CE1 1 ATOM 1085 C CE2 . TYR A 1 133 ? -8.717 42.706 -12.730 1.00 365.21 ? 849 TYR A CE2 1 ATOM 1086 C CZ . TYR A 1 133 ? -7.664 42.177 -12.011 1.00 365.64 ? 849 TYR A CZ 1 ATOM 1087 O OH . TYR A 1 133 ? -6.820 43.008 -11.310 1.00 370.43 ? 849 TYR A OH 1 ATOM 1088 N N . GLY A 1 134 ? -11.176 38.009 -17.181 1.00 337.38 ? 850 GLY A N 1 ATOM 1089 C CA . GLY A 1 134 ? -11.889 36.847 -17.666 1.00 335.73 ? 850 GLY A CA 1 ATOM 1090 C C . GLY A 1 134 ? -13.224 36.648 -16.968 1.00 334.96 ? 850 GLY A C 1 ATOM 1091 O O . GLY A 1 134 ? -13.770 37.547 -16.318 1.00 334.50 ? 850 GLY A O 1 ATOM 1092 N N . SER A 1 135 ? -13.751 35.433 -17.106 1.00 332.00 ? 851 SER A N 1 ATOM 1093 C CA . SER A 1 135 ? -15.057 35.074 -16.568 1.00 331.29 ? 851 SER A CA 1 ATOM 1094 C C . SER A 1 135 ? -15.010 34.031 -15.460 1.00 327.43 ? 851 SER A C 1 ATOM 1095 O O . SER A 1 135 ? -15.841 34.084 -14.551 1.00 326.40 ? 851 SER A O 1 ATOM 1096 C CB . SER A 1 135 ? -15.968 34.552 -17.692 1.00 332.98 ? 851 SER A CB 1 ATOM 1097 O OG . SER A 1 135 ? -15.416 33.398 -18.300 1.00 331.24 ? 851 SER A OG 1 ATOM 1098 N N . HIS A 1 136 ? -14.071 33.088 -15.510 1.00 330.57 ? 852 HIS A N 1 ATOM 1099 C CA . HIS A 1 136 ? -13.992 32.004 -14.541 1.00 330.47 ? 852 HIS A CA 1 ATOM 1100 C C . HIS A 1 136 ? -12.575 31.901 -13.992 1.00 331.25 ? 852 HIS A C 1 ATOM 1101 O O . HIS A 1 136 ? -11.668 32.638 -14.393 1.00 330.62 ? 852 HIS A O 1 ATOM 1102 C CB . HIS A 1 136 ? -14.398 30.660 -15.165 1.00 329.33 ? 852 HIS A CB 1 ATOM 1103 C CG . HIS A 1 136 ? -15.815 30.611 -15.641 1.00 326.96 ? 852 HIS A CG 1 ATOM 1104 N ND1 . HIS A 1 136 ? -16.272 31.368 -16.697 1.00 323.32 ? 852 HIS A ND1 1 ATOM 1105 C CD2 . HIS A 1 136 ? -16.873 29.882 -15.213 1.00 326.01 ? 852 HIS A CD2 1 ATOM 1106 C CE1 . HIS A 1 136 ? -17.553 31.115 -16.894 1.00 324.20 ? 852 HIS A CE1 1 ATOM 1107 N NE2 . HIS A 1 136 ? -17.943 30.217 -16.007 1.00 324.43 ? 852 HIS A NE2 1 ATOM 1108 N N . TYR A 1 137 ? -12.395 30.975 -13.055 1.00 332.86 ? 853 TYR A N 1 ATOM 1109 C CA . TYR A 1 137 ? -11.083 30.475 -12.680 1.00 333.73 ? 853 TYR A CA 1 ATOM 1110 C C . TYR A 1 137 ? -11.088 28.960 -12.818 1.00 335.27 ? 853 TYR A C 1 ATOM 1111 O O . TYR A 1 137 ? -12.109 28.304 -12.593 1.00 335.13 ? 853 TYR A O 1 ATOM 1112 C CB . TYR A 1 137 ? -10.687 30.888 -11.249 1.00 332.82 ? 853 TYR A CB 1 ATOM 1113 C CG . TYR A 1 137 ? -11.502 30.256 -10.139 1.00 333.09 ? 853 TYR A CG 1 ATOM 1114 C CD1 . TYR A 1 137 ? -11.141 29.028 -9.594 1.00 333.96 ? 853 TYR A CD1 1 ATOM 1115 C CD2 . TYR A 1 137 ? -12.617 30.899 -9.619 1.00 332.73 ? 853 TYR A CD2 1 ATOM 1116 C CE1 . TYR A 1 137 ? -11.878 28.451 -8.578 1.00 333.27 ? 853 TYR A CE1 1 ATOM 1117 C CE2 . TYR A 1 137 ? -13.358 30.331 -8.601 1.00 332.53 ? 853 TYR A CE2 1 ATOM 1118 C CZ . TYR A 1 137 ? -12.984 29.108 -8.083 1.00 332.51 ? 853 TYR A CZ 1 ATOM 1119 O OH . TYR A 1 137 ? -13.721 28.538 -7.070 1.00 333.87 ? 853 TYR A OH 1 ATOM 1120 N N . ILE A 1 138 ? -9.944 28.411 -13.207 1.00 343.99 ? 854 ILE A N 1 ATOM 1121 C CA . ILE A 1 138 ? -9.833 26.977 -13.447 1.00 342.71 ? 854 ILE A CA 1 ATOM 1122 C C . ILE A 1 138 ? -9.734 26.255 -12.112 1.00 340.49 ? 854 ILE A C 1 ATOM 1123 O O . ILE A 1 138 ? -8.866 26.564 -11.288 1.00 342.19 ? 854 ILE A O 1 ATOM 1124 C CB . ILE A 1 138 ? -8.621 26.666 -14.339 1.00 341.43 ? 854 ILE A CB 1 ATOM 1125 C CG1 . ILE A 1 138 ? -8.708 27.462 -15.642 1.00 340.87 ? 854 ILE A CG1 1 ATOM 1126 C CG2 . ILE A 1 138 ? -8.544 25.175 -14.628 1.00 341.89 ? 854 ILE A CG2 1 ATOM 1127 C CD1 . ILE A 1 138 ? -7.470 27.359 -16.502 1.00 342.45 ? 854 ILE A CD1 1 ATOM 1128 N N . ALA A 1 139 ? -10.628 25.292 -11.894 1.00 348.36 ? 855 ALA A N 1 ATOM 1129 C CA . ALA A 1 139 ? -10.659 24.510 -10.664 1.00 347.62 ? 855 ALA A CA 1 ATOM 1130 C C . ALA A 1 139 ? -9.932 23.179 -10.789 1.00 347.30 ? 855 ALA A C 1 ATOM 1131 O O . ALA A 1 139 ? -9.189 22.793 -9.881 1.00 348.92 ? 855 ALA A O 1 ATOM 1132 C CB . ALA A 1 139 ? -12.108 24.264 -10.235 1.00 350.06 ? 855 ALA A CB 1 ATOM 1133 N N . GLU A 1 140 ? -10.132 22.467 -11.895 1.00 339.61 ? 856 GLU A N 1 ATOM 1134 C CA . GLU A 1 140 ? -9.475 21.193 -12.142 1.00 342.92 ? 856 GLU A CA 1 ATOM 1135 C C . GLU A 1 140 ? -8.963 21.181 -13.574 1.00 339.83 ? 856 GLU A C 1 ATOM 1136 O O . GLU A 1 140 ? -9.662 21.622 -14.491 1.00 340.73 ? 856 GLU A O 1 ATOM 1137 C CB . GLU A 1 140 ? -10.432 20.018 -11.905 1.00 350.54 ? 856 GLU A CB 1 ATOM 1138 C CG . GLU A 1 140 ? -9.783 18.650 -12.007 1.00 359.83 ? 856 GLU A CG 1 ATOM 1139 C CD . GLU A 1 140 ? -10.772 17.518 -11.806 1.00 370.46 ? 856 GLU A CD 1 ATOM 1140 O OE1 . GLU A 1 140 ? -11.903 17.615 -12.328 1.00 381.32 ? 856 GLU A OE1 1 ATOM 1141 O OE2 . GLU A 1 140 ? -10.420 16.536 -11.119 1.00 375.41 ? 856 GLU A OE2 1 ATOM 1142 N N . ALA A 1 141 ? -7.743 20.681 -13.764 1.00 360.66 ? 857 ALA A N 1 ATOM 1143 C CA . ALA A 1 141 ? -7.126 20.686 -15.082 1.00 353.78 ? 857 ALA A CA 1 ATOM 1144 C C . ALA A 1 141 ? -6.156 19.522 -15.206 1.00 351.42 ? 857 ALA A C 1 ATOM 1145 O O . ALA A 1 141 ? -5.604 19.043 -14.212 1.00 351.49 ? 857 ALA A O 1 ATOM 1146 C CB . ALA A 1 141 ? -6.398 22.007 -15.355 1.00 352.66 ? 857 ALA A CB 1 ATOM 1147 N N . LEU A 1 142 ? -5.951 19.081 -16.444 1.00 353.86 ? 858 LEU A N 1 ATOM 1148 C CA . LEU A 1 142 ? -5.030 18.002 -16.769 1.00 350.76 ? 858 LEU A CA 1 ATOM 1149 C C . LEU A 1 142 ? -3.838 18.567 -17.530 1.00 349.62 ? 858 LEU A C 1 ATOM 1150 O O . LEU A 1 142 ? -4.012 19.263 -18.537 1.00 346.99 ? 858 LEU A O 1 ATOM 1151 C CB . LEU A 1 142 ? -5.721 16.921 -17.601 1.00 350.00 ? 858 LEU A CB 1 ATOM 1152 C CG . LEU A 1 142 ? -4.852 15.749 -18.064 1.00 352.22 ? 858 LEU A CG 1 ATOM 1153 C CD1 . LEU A 1 142 ? -4.380 14.931 -16.876 1.00 353.38 ? 858 LEU A CD1 1 ATOM 1154 C CD2 . LEU A 1 142 ? -5.602 14.876 -19.059 1.00 354.72 ? 858 LEU A CD2 1 ATOM 1155 N N . TYR A 1 143 ? -2.639 18.271 -17.044 1.00 352.89 ? 859 TYR A N 1 ATOM 1156 C CA . TYR A 1 143 ? -1.396 18.667 -17.684 1.00 350.52 ? 859 TYR A CA 1 ATOM 1157 C C . TYR A 1 143 ? -0.659 17.432 -18.179 1.00 351.72 ? 859 TYR A C 1 ATOM 1158 O O . TYR A 1 143 ? -0.941 16.305 -17.768 1.00 352.36 ? 859 TYR A O 1 ATOM 1159 C CB . TYR A 1 143 ? -0.506 19.458 -16.716 1.00 349.14 ? 859 TYR A CB 1 ATOM 1160 C CG . TYR A 1 143 ? -0.977 20.874 -16.451 1.00 348.57 ? 859 TYR A CG 1 ATOM 1161 C CD1 . TYR A 1 143 ? -2.096 21.121 -15.664 1.00 348.21 ? 859 TYR A CD1 1 ATOM 1162 C CD2 . TYR A 1 143 ? -0.296 21.964 -16.982 1.00 347.50 ? 859 TYR A CD2 1 ATOM 1163 C CE1 . TYR A 1 143 ? -2.528 22.415 -15.419 1.00 347.29 ? 859 TYR A CE1 1 ATOM 1164 C CE2 . TYR A 1 143 ? -0.721 23.260 -16.742 1.00 346.09 ? 859 TYR A CE2 1 ATOM 1165 C CZ . TYR A 1 143 ? -1.835 23.480 -15.960 1.00 346.43 ? 859 TYR A CZ 1 ATOM 1166 O OH . TYR A 1 143 ? -2.255 24.767 -15.721 1.00 350.25 ? 859 TYR A OH 1 ATOM 1167 N N . GLY A 1 144 ? 0.286 17.656 -19.069 1.00 350.26 ? 860 GLY A N 1 ATOM 1168 C CA . GLY A 1 144 ? 1.114 16.571 -19.547 1.00 349.74 ? 860 GLY A CA 1 ATOM 1169 C C . GLY A 1 144 ? 1.641 16.868 -20.938 1.00 349.64 ? 860 GLY A C 1 ATOM 1170 O O . GLY A 1 144 ? 1.777 18.026 -21.326 1.00 345.76 ? 860 GLY A O 1 ATOM 1171 N N . SER A 1 145 ? 1.932 15.789 -21.660 1.00 331.68 ? 861 SER A N 1 ATOM 1172 C CA . SER A 1 145 ? 2.441 15.856 -23.024 1.00 335.21 ? 861 SER A CA 1 ATOM 1173 C C . SER A 1 145 ? 1.619 14.909 -23.882 1.00 338.36 ? 861 SER A C 1 ATOM 1174 O O . SER A 1 145 ? 1.629 13.696 -23.650 1.00 346.15 ? 861 SER A O 1 ATOM 1175 C CB . SER A 1 145 ? 3.924 15.481 -23.080 1.00 337.81 ? 861 SER A CB 1 ATOM 1176 O OG . SER A 1 145 ? 4.699 16.301 -22.221 1.00 342.87 ? 861 SER A OG 1 ATOM 1177 N N . GLU A 1 146 ? 0.906 15.453 -24.865 1.00 340.66 ? 862 GLU A N 1 ATOM 1178 C CA . GLU A 1 146 ? 0.094 14.644 -25.763 1.00 340.33 ? 862 GLU A CA 1 ATOM 1179 C C . GLU A 1 146 ? 0.521 14.882 -27.205 1.00 334.60 ? 862 GLU A C 1 ATOM 1180 O O . GLU A 1 146 ? 0.745 16.027 -27.619 1.00 332.14 ? 862 GLU A O 1 ATOM 1181 C CB . GLU A 1 146 ? -1.410 14.921 -25.569 1.00 344.18 ? 862 GLU A CB 1 ATOM 1182 C CG . GLU A 1 146 ? -2.020 16.011 -26.443 1.00 345.70 ? 862 GLU A CG 1 ATOM 1183 C CD . GLU A 1 146 ? -3.516 16.167 -26.225 1.00 348.08 ? 862 GLU A CD 1 ATOM 1184 O OE1 . GLU A 1 146 ? -4.113 15.309 -25.537 1.00 345.34 ? 862 GLU A OE1 1 ATOM 1185 O OE2 . GLU A 1 146 ? -4.096 17.147 -26.738 1.00 353.11 ? 862 GLU A OE2 1 ATOM 1186 N N . LEU A 1 147 ? 0.670 13.791 -27.948 1.00 334.96 ? 863 LEU A N 1 ATOM 1187 C CA . LEU A 1 147 ? 0.978 13.811 -29.369 1.00 333.52 ? 863 LEU A CA 1 ATOM 1188 C C . LEU A 1 147 ? -0.267 13.376 -30.127 1.00 337.16 ? 863 LEU A C 1 ATOM 1189 O O . LEU A 1 147 ? -0.715 12.233 -29.984 1.00 340.61 ? 863 LEU A O 1 ATOM 1190 C CB . LEU A 1 147 ? 2.154 12.889 -29.691 1.00 331.76 ? 863 LEU A CB 1 ATOM 1191 C CG . LEU A 1 147 ? 2.437 12.585 -31.164 1.00 331.79 ? 863 LEU A CG 1 ATOM 1192 C CD1 . LEU A 1 147 ? 2.841 13.838 -31.926 1.00 331.92 ? 863 LEU A CD1 1 ATOM 1193 C CD2 . LEU A 1 147 ? 3.512 11.519 -31.279 1.00 333.02 ? 863 LEU A CD2 1 ATOM 1194 N N . THR A 1 148 ? -0.828 14.284 -30.917 1.00 330.69 ? 864 THR A N 1 ATOM 1195 C CA . THR A 1 148 ? -2.026 14.014 -31.699 1.00 327.04 ? 864 THR A CA 1 ATOM 1196 C C . THR A 1 148 ? -1.648 13.984 -33.171 1.00 327.02 ? 864 THR A C 1 ATOM 1197 O O . THR A 1 148 ? -1.218 15.001 -33.726 1.00 325.35 ? 864 THR A O 1 ATOM 1198 C CB . THR A 1 148 ? -3.105 15.066 -31.441 1.00 328.64 ? 864 THR A CB 1 ATOM 1199 O OG1 . THR A 1 148 ? -3.268 15.248 -30.027 1.00 333.12 ? 864 THR A OG1 1 ATOM 1200 C CG2 . THR A 1 148 ? -4.430 14.620 -32.041 1.00 328.95 ? 864 THR A CG2 1 ATOM 1201 N N . CYS A 1 149 ? -1.797 12.820 -33.792 1.00 315.91 ? 865 CYS A N 1 ATOM 1202 C CA . CYS A 1 149 ? -1.496 12.636 -35.201 1.00 318.55 ? 865 CYS A CA 1 ATOM 1203 C C . CYS A 1 149 ? -2.761 12.245 -35.949 1.00 317.20 ? 865 CYS A C 1 ATOM 1204 O O . CYS A 1 149 ? -3.677 11.642 -35.383 1.00 320.67 ? 865 CYS A O 1 ATOM 1205 C CB . CYS A 1 149 ? -0.421 11.563 -35.403 1.00 323.09 ? 865 CYS A CB 1 ATOM 1206 S SG . CYS A 1 149 ? 1.188 11.929 -34.666 1.00 337.44 ? 865 CYS A SG 1 ATOM 1207 N N . ILE A 1 150 ? -2.803 12.599 -37.229 1.00 309.85 ? 866 ILE A N 1 ATOM 1208 C CA . ILE A 1 150 ? -3.950 12.328 -38.088 1.00 306.28 ? 866 ILE A CA 1 ATOM 1209 C C . ILE A 1 150 ? -3.444 11.690 -39.372 1.00 303.27 ? 866 ILE A C 1 ATOM 1210 O O . ILE A 1 150 ? -2.674 12.310 -40.115 1.00 303.47 ? 866 ILE A O 1 ATOM 1211 C CB . ILE A 1 150 ? -4.753 13.601 -38.398 1.00 306.54 ? 866 ILE A CB 1 ATOM 1212 C CG1 . ILE A 1 150 ? -5.474 14.094 -37.142 1.00 308.02 ? 866 ILE A CG1 1 ATOM 1213 C CG2 . ILE A 1 150 ? -5.741 13.350 -39.525 1.00 308.35 ? 866 ILE A CG2 1 ATOM 1214 C CD1 . ILE A 1 150 ? -6.230 15.388 -37.342 1.00 312.26 ? 866 ILE A CD1 1 ATOM 1215 N N . ILE A 1 151 ? -3.876 10.462 -39.634 1.00 300.75 ? 867 ILE A N 1 ATOM 1216 C CA . ILE A 1 151 ? -3.520 9.756 -40.859 1.00 303.23 ? 867 ILE A CA 1 ATOM 1217 C C . ILE A 1 151 ? -4.575 10.066 -41.912 1.00 306.23 ? 867 ILE A C 1 ATOM 1218 O O . ILE A 1 151 ? -5.761 9.780 -41.719 1.00 305.99 ? 867 ILE A O 1 ATOM 1219 C CB . ILE A 1 151 ? -3.409 8.243 -40.622 1.00 303.87 ? 867 ILE A CB 1 ATOM 1220 C CG1 . ILE A 1 151 ? -2.660 7.958 -39.320 1.00 304.74 ? 867 ILE A CG1 1 ATOM 1221 C CG2 . ILE A 1 151 ? -2.698 7.585 -41.790 1.00 304.41 ? 867 ILE A CG2 1 ATOM 1222 C CD1 . ILE A 1 151 ? -2.704 6.508 -38.896 1.00 304.63 ? 867 ILE A CD1 1 ATOM 1223 N N . HIS A 1 152 ? -4.145 10.649 -43.029 1.00 304.77 ? 868 HIS A N 1 ATOM 1224 C CA . HIS A 1 152 ? -5.037 11.014 -44.124 1.00 305.11 ? 868 HIS A CA 1 ATOM 1225 C C . HIS A 1 152 ? -4.963 9.934 -45.197 1.00 306.41 ? 868 HIS A C 1 ATOM 1226 O O . HIS A 1 152 ? -3.944 9.798 -45.883 1.00 306.20 ? 868 HIS A O 1 ATOM 1227 C CB . HIS A 1 152 ? -4.666 12.380 -44.697 1.00 303.48 ? 868 HIS A CB 1 ATOM 1228 C CG . HIS A 1 152 ? -4.783 13.502 -43.712 1.00 304.01 ? 868 HIS A CG 1 ATOM 1229 N ND1 . HIS A 1 152 ? -5.947 14.217 -43.534 1.00 308.20 ? 868 HIS A ND1 1 ATOM 1230 C CD2 . HIS A 1 152 ? -3.880 14.034 -42.855 1.00 307.28 ? 868 HIS A CD2 1 ATOM 1231 C CE1 . HIS A 1 152 ? -5.758 15.140 -42.608 1.00 309.31 ? 868 HIS A CE1 1 ATOM 1232 N NE2 . HIS A 1 152 ? -4.512 15.050 -42.180 1.00 310.90 ? 868 HIS A NE2 1 ATOM 1233 N N . PHE A 1 153 ? -6.048 9.165 -45.343 1.00 304.46 ? 869 PHE A N 1 ATOM 1234 C CA . PHE A 1 153 ? -6.119 8.167 -46.396 1.00 305.02 ? 869 PHE A CA 1 ATOM 1235 C C . PHE A 1 153 ? -6.866 8.722 -47.603 1.00 308.56 ? 869 PHE A C 1 ATOM 1236 O O . PHE A 1 153 ? -7.751 9.571 -47.457 1.00 307.24 ? 869 PHE A O 1 ATOM 1237 C CB . PHE A 1 153 ? -6.828 6.901 -45.906 1.00 305.03 ? 869 PHE A CB 1 ATOM 1238 C CG . PHE A 1 153 ? -6.192 6.273 -44.699 1.00 305.54 ? 869 PHE A CG 1 ATOM 1239 C CD1 . PHE A 1 153 ? -6.599 6.629 -43.424 1.00 305.82 ? 869 PHE A CD1 1 ATOM 1240 C CD2 . PHE A 1 153 ? -5.198 5.318 -44.837 1.00 305.26 ? 869 PHE A CD2 1 ATOM 1241 C CE1 . PHE A 1 153 ? -6.022 6.051 -42.309 1.00 305.25 ? 869 PHE A CE1 1 ATOM 1242 C CE2 . PHE A 1 153 ? -4.617 4.735 -43.725 1.00 304.43 ? 869 PHE A CE2 1 ATOM 1243 C CZ . PHE A 1 153 ? -5.032 5.102 -42.460 1.00 304.63 ? 869 PHE A CZ 1 ATOM 1244 N N . PRO A 1 154 ? -6.532 8.269 -48.814 1.00 306.21 ? 870 PRO A N 1 ATOM 1245 C CA . PRO A 1 154 ? -7.257 8.755 -49.997 1.00 304.14 ? 870 PRO A CA 1 ATOM 1246 C C . PRO A 1 154 ? -8.650 8.165 -50.136 1.00 305.13 ? 870 PRO A C 1 ATOM 1247 O O . PRO A 1 154 ? -9.501 8.785 -50.786 1.00 307.97 ? 870 PRO A O 1 ATOM 1248 C CB . PRO A 1 154 ? -6.357 8.329 -51.169 1.00 303.25 ? 870 PRO A CB 1 ATOM 1249 C CG . PRO A 1 154 ? -5.061 7.864 -50.546 1.00 303.06 ? 870 PRO A CG 1 ATOM 1250 C CD . PRO A 1 154 ? -5.411 7.388 -49.178 1.00 304.90 ? 870 PRO A CD 1 ATOM 1251 N N . SER A 1 155 ? -8.912 6.998 -49.551 1.00 303.76 ? 871 SER A N 1 ATOM 1252 C CA . SER A 1 155 ? -10.203 6.347 -49.723 1.00 304.29 ? 871 SER A CA 1 ATOM 1253 C C . SER A 1 155 ? -10.440 5.379 -48.575 1.00 304.57 ? 871 SER A C 1 ATOM 1254 O O . SER A 1 155 ? -9.512 4.985 -47.864 1.00 304.11 ? 871 SER A O 1 ATOM 1255 C CB . SER A 1 155 ? -10.283 5.607 -51.061 1.00 304.40 ? 871 SER A CB 1 ATOM 1256 O OG . SER A 1 155 ? -9.477 4.441 -51.040 1.00 303.99 ? 871 SER A OG 1 ATOM 1257 N N . LYS A 1 156 ? -11.708 4.996 -48.414 1.00 311.48 ? 872 LYS A N 1 ATOM 1258 C CA . LYS A 1 156 ? -12.072 3.989 -47.424 1.00 311.91 ? 872 LYS A CA 1 ATOM 1259 C C . LYS A 1 156 ? -11.522 2.618 -47.796 1.00 314.59 ? 872 LYS A C 1 ATOM 1260 O O . LYS A 1 156 ? -11.234 1.802 -46.913 1.00 315.41 ? 872 LYS A O 1 ATOM 1261 C CB . LYS A 1 156 ? -13.594 3.938 -47.281 1.00 312.88 ? 872 LYS A CB 1 ATOM 1262 C CG . LYS A 1 156 ? -14.110 3.077 -46.144 1.00 317.20 ? 872 LYS A CG 1 ATOM 1263 C CD . LYS A 1 156 ? -15.630 3.025 -46.166 1.00 323.06 ? 872 LYS A CD 1 ATOM 1264 C CE . LYS A 1 156 ? -16.179 2.216 -45.004 1.00 328.70 ? 872 LYS A CE 1 ATOM 1265 N NZ . LYS A 1 156 ? -17.653 2.034 -45.117 1.00 331.60 ? 872 LYS A NZ 1 ATOM 1266 N N . LYS A 1 157 ? -11.366 2.351 -49.094 1.00 309.77 ? 873 LYS A N 1 ATOM 1267 C CA . LYS A 1 157 ? -10.833 1.067 -49.537 1.00 312.78 ? 873 LYS A CA 1 ATOM 1268 C C . LYS A 1 157 ? -9.340 0.962 -49.252 1.00 311.55 ? 873 LYS A C 1 ATOM 1269 O O . LYS A 1 157 ? -8.860 -0.079 -48.786 1.00 308.46 ? 873 LYS A O 1 ATOM 1270 C CB . LYS A 1 157 ? -11.117 0.877 -51.028 1.00 320.99 ? 873 LYS A CB 1 ATOM 1271 C CG . LYS A 1 157 ? -10.441 -0.329 -51.659 1.00 327.32 ? 873 LYS A CG 1 ATOM 1272 C CD . LYS A 1 157 ? -10.770 -0.413 -53.142 1.00 334.37 ? 873 LYS A CD 1 ATOM 1273 C CE . LYS A 1 157 ? -9.936 -1.471 -53.845 1.00 335.61 ? 873 LYS A CE 1 ATOM 1274 N NZ . LYS A 1 157 ? -10.218 -1.503 -55.307 1.00 331.88 ? 873 LYS A NZ 1 ATOM 1275 N N . VAL A 1 158 ? -8.590 2.034 -49.525 1.00 305.62 ? 874 VAL A N 1 ATOM 1276 C CA . VAL A 1 158 ? -7.145 2.017 -49.312 1.00 305.97 ? 874 VAL A CA 1 ATOM 1277 C C . VAL A 1 158 ? -6.819 1.724 -47.853 1.00 307.61 ? 874 VAL A C 1 ATOM 1278 O O . VAL A 1 158 ? -5.890 0.966 -47.549 1.00 309.24 ? 874 VAL A O 1 ATOM 1279 C CB . VAL A 1 158 ? -6.522 3.348 -49.778 1.00 306.82 ? 874 VAL A CB 1 ATOM 1280 C CG1 . VAL A 1 158 ? -5.130 3.528 -49.190 1.00 308.16 ? 874 VAL A CG1 1 ATOM 1281 C CG2 . VAL A 1 158 ? -6.466 3.398 -51.297 1.00 308.23 ? 874 VAL A CG2 1 ATOM 1282 N N . GLN A 1 159 ? -7.587 2.303 -46.929 1.00 296.91 ? 875 GLN A N 1 ATOM 1283 C CA . GLN A 1 159 ? -7.336 2.070 -45.511 1.00 299.79 ? 875 GLN A CA 1 ATOM 1284 C C . GLN A 1 159 ? -7.596 0.620 -45.130 1.00 300.22 ? 875 GLN A C 1 ATOM 1285 O O . GLN A 1 159 ? -6.746 -0.026 -44.504 1.00 303.90 ? 875 GLN A O 1 ATOM 1286 C CB . GLN A 1 159 ? -8.196 2.997 -44.657 1.00 303.92 ? 875 GLN A CB 1 ATOM 1287 C CG . GLN A 1 159 ? -8.374 2.477 -43.244 1.00 307.70 ? 875 GLN A CG 1 ATOM 1288 C CD . GLN A 1 159 ? -8.717 3.568 -42.267 1.00 319.03 ? 875 GLN A CD 1 ATOM 1289 O OE1 . GLN A 1 159 ? -9.145 4.653 -42.659 1.00 336.49 ? 875 GLN A OE1 1 ATOM 1290 N NE2 . GLN A 1 159 ? -8.518 3.294 -40.984 1.00 322.39 ? 875 GLN A NE2 1 ATOM 1291 N N . GLN A 1 160 ? -8.774 0.101 -45.480 1.00 310.50 ? 876 GLN A N 1 ATOM 1292 C CA . GLN A 1 160 ? -9.126 -1.268 -45.113 1.00 310.32 ? 876 GLN A CA 1 ATOM 1293 C C . GLN A 1 160 ? -8.078 -2.253 -45.606 1.00 311.31 ? 876 GLN A C 1 ATOM 1294 O O . GLN A 1 160 ? -7.685 -3.171 -44.877 1.00 309.89 ? 876 GLN A O 1 ATOM 1295 C CB . GLN A 1 160 ? -10.509 -1.619 -45.666 1.00 310.63 ? 876 GLN A CB 1 ATOM 1296 C CG . GLN A 1 160 ? -11.656 -1.005 -44.877 1.00 313.51 ? 876 GLN A CG 1 ATOM 1297 C CD . GLN A 1 160 ? -12.987 -1.089 -45.600 1.00 316.96 ? 876 GLN A CD 1 ATOM 1298 O OE1 . GLN A 1 160 ? -13.049 -0.977 -46.825 1.00 324.05 ? 876 GLN A OE1 1 ATOM 1299 N NE2 . GLN A 1 160 ? -14.060 -1.284 -44.843 1.00 318.56 ? 876 GLN A NE2 1 ATOM 1300 N N . GLN A 1 161 ? -7.595 -2.065 -46.834 1.00 328.06 ? 877 GLN A N 1 ATOM 1301 C CA . GLN A 1 161 ? -6.505 -2.893 -47.330 1.00 326.32 ? 877 GLN A CA 1 ATOM 1302 C C . GLN A 1 161 ? -5.263 -2.728 -46.467 1.00 321.88 ? 877 GLN A C 1 ATOM 1303 O O . GLN A 1 161 ? -4.615 -3.711 -46.097 1.00 326.32 ? 877 GLN A O 1 ATOM 1304 C CB . GLN A 1 161 ? -6.197 -2.540 -48.788 1.00 331.41 ? 877 GLN A CB 1 ATOM 1305 C CG . GLN A 1 161 ? -7.311 -2.868 -49.763 1.00 335.46 ? 877 GLN A CG 1 ATOM 1306 C CD . GLN A 1 161 ? -6.880 -2.725 -51.212 1.00 339.62 ? 877 GLN A CD 1 ATOM 1307 O OE1 . GLN A 1 161 ? -7.274 -1.783 -51.900 1.00 338.41 ? 877 GLN A OE1 1 ATOM 1308 N NE2 . GLN A 1 161 ? -6.063 -3.662 -51.681 1.00 342.26 ? 877 GLN A NE2 1 ATOM 1309 N N . LEU A 1 162 ? -4.923 -1.483 -46.127 1.00 329.56 ? 878 LEU A N 1 ATOM 1310 C CA . LEU A 1 162 ? -3.739 -1.234 -45.316 1.00 326.49 ? 878 LEU A CA 1 ATOM 1311 C C . LEU A 1 162 ? -3.908 -1.774 -43.904 1.00 326.55 ? 878 LEU A C 1 ATOM 1312 O O . LEU A 1 162 ? -2.953 -2.290 -43.313 1.00 328.78 ? 878 LEU A O 1 ATOM 1313 C CB . LEU A 1 162 ? -3.426 0.264 -45.292 1.00 323.72 ? 878 LEU A CB 1 ATOM 1314 C CG . LEU A 1 162 ? -2.816 0.819 -46.579 1.00 322.67 ? 878 LEU A CG 1 ATOM 1315 C CD1 . LEU A 1 162 ? -2.476 2.294 -46.430 1.00 323.00 ? 878 LEU A CD1 1 ATOM 1316 C CD2 . LEU A 1 162 ? -1.585 0.015 -46.931 1.00 322.36 ? 878 LEU A CD2 1 ATOM 1317 N N . TRP A 1 163 ? -5.118 -1.677 -43.353 1.00 324.26 ? 879 TRP A N 1 ATOM 1318 C CA . TRP A 1 163 ? -5.358 -2.191 -42.010 1.00 326.45 ? 879 TRP A CA 1 ATOM 1319 C C . TRP A 1 163 ? -5.288 -3.714 -41.980 1.00 330.65 ? 879 TRP A C 1 ATOM 1320 O O . TRP A 1 163 ? -4.691 -4.295 -41.066 1.00 334.71 ? 879 TRP A O 1 ATOM 1321 C CB . TRP A 1 163 ? -6.711 -1.699 -41.493 1.00 325.16 ? 879 TRP A CB 1 ATOM 1322 C CG . TRP A 1 163 ? -7.083 -2.266 -40.163 1.00 322.88 ? 879 TRP A CG 1 ATOM 1323 C CD1 . TRP A 1 163 ? -7.971 -3.271 -39.924 1.00 322.57 ? 879 TRP A CD1 1 ATOM 1324 C CD2 . TRP A 1 163 ? -6.573 -1.867 -38.884 1.00 324.47 ? 879 TRP A CD2 1 ATOM 1325 N NE1 . TRP A 1 163 ? -8.051 -3.522 -38.576 1.00 324.32 ? 879 TRP A NE1 1 ATOM 1326 C CE2 . TRP A 1 163 ? -7.202 -2.674 -37.915 1.00 322.88 ? 879 TRP A CE2 1 ATOM 1327 C CE3 . TRP A 1 163 ? -5.648 -0.906 -38.464 1.00 327.87 ? 879 TRP A CE3 1 ATOM 1328 C CZ2 . TRP A 1 163 ? -6.937 -2.549 -36.552 1.00 322.03 ? 879 TRP A CZ2 1 ATOM 1329 C CZ3 . TRP A 1 163 ? -5.386 -0.784 -37.109 1.00 327.08 ? 879 TRP A CZ3 1 ATOM 1330 C CH2 . TRP A 1 163 ? -6.029 -1.602 -36.170 1.00 324.44 ? 879 TRP A CH2 1 ATOM 1331 N N . LEU A 1 164 ? -5.885 -4.377 -42.973 1.00 329.70 ? 880 LEU A N 1 ATOM 1332 C CA . LEU A 1 164 ? -5.776 -5.830 -43.054 1.00 330.46 ? 880 LEU A CA 1 ATOM 1333 C C . LEU A 1 164 ? -4.356 -6.258 -43.401 1.00 328.51 ? 880 LEU A C 1 ATOM 1334 O O . LEU A 1 164 ? -3.878 -7.290 -42.916 1.00 327.68 ? 880 LEU A O 1 ATOM 1335 C CB . LEU A 1 164 ? -6.774 -6.386 -44.074 1.00 332.20 ? 880 LEU A CB 1 ATOM 1336 C CG . LEU A 1 164 ? -8.191 -6.735 -43.598 1.00 335.94 ? 880 LEU A CG 1 ATOM 1337 C CD1 . LEU A 1 164 ? -8.186 -7.213 -42.149 1.00 338.34 ? 880 LEU A CD1 1 ATOM 1338 C CD2 . LEU A 1 164 ? -9.181 -5.589 -43.785 1.00 336.50 ? 880 LEU A CD2 1 ATOM 1339 N N . GLN A 1 165 ? -3.668 -5.482 -44.241 1.00 332.49 ? 881 GLN A N 1 ATOM 1340 C CA . GLN A 1 165 ? -2.271 -5.773 -44.548 1.00 333.99 ? 881 GLN A CA 1 ATOM 1341 C C . GLN A 1 165 ? -1.393 -5.601 -43.315 1.00 335.40 ? 881 GLN A C 1 ATOM 1342 O O . GLN A 1 165 ? -0.445 -6.367 -43.105 1.00 336.90 ? 881 GLN A O 1 ATOM 1343 C CB . GLN A 1 165 ? -1.791 -4.870 -45.687 1.00 334.32 ? 881 GLN A CB 1 ATOM 1344 C CG . GLN A 1 165 ? -0.368 -5.113 -46.150 1.00 335.91 ? 881 GLN A CG 1 ATOM 1345 C CD . GLN A 1 165 ? 0.030 -4.191 -47.289 1.00 337.97 ? 881 GLN A CD 1 ATOM 1346 O OE1 . GLN A 1 165 ? -0.627 -4.152 -48.329 1.00 339.37 ? 881 GLN A OE1 1 ATOM 1347 N NE2 . GLN A 1 165 ? 1.104 -3.435 -47.092 1.00 338.44 ? 881 GLN A NE2 1 ATOM 1348 N N . TYR A 1 166 ? -1.699 -4.601 -42.488 1.00 337.48 ? 882 TYR A N 1 ATOM 1349 C CA . TYR A 1 166 ? -0.973 -4.411 -41.236 1.00 335.81 ? 882 TYR A CA 1 ATOM 1350 C C . TYR A 1 166 ? -1.296 -5.515 -40.240 1.00 337.46 ? 882 TYR A C 1 ATOM 1351 O O . TYR A 1 166 ? -0.405 -6.004 -39.536 1.00 335.58 ? 882 TYR A O 1 ATOM 1352 C CB . TYR A 1 166 ? -1.305 -3.034 -40.659 1.00 333.51 ? 882 TYR A CB 1 ATOM 1353 C CG . TYR A 1 166 ? -1.125 -2.886 -39.163 1.00 330.59 ? 882 TYR A CG 1 ATOM 1354 C CD1 . TYR A 1 166 ? 0.139 -2.762 -38.602 1.00 331.37 ? 882 TYR A CD1 1 ATOM 1355 C CD2 . TYR A 1 166 ? -2.226 -2.836 -38.315 1.00 327.03 ? 882 TYR A CD2 1 ATOM 1356 C CE1 . TYR A 1 166 ? 0.303 -2.612 -37.237 1.00 328.55 ? 882 TYR A CE1 1 ATOM 1357 C CE2 . TYR A 1 166 ? -2.071 -2.686 -36.950 1.00 325.36 ? 882 TYR A CE2 1 ATOM 1358 C CZ . TYR A 1 166 ? -0.804 -2.574 -36.416 1.00 326.10 ? 882 TYR A CZ 1 ATOM 1359 O OH . TYR A 1 166 ? -0.643 -2.424 -35.058 1.00 324.14 ? 882 TYR A OH 1 ATOM 1360 N N . GLN A 1 167 ? -2.561 -5.931 -40.180 1.00 322.14 ? 883 GLN A N 1 ATOM 1361 C CA . GLN A 1 167 ? -2.967 -6.944 -39.213 1.00 326.94 ? 883 GLN A CA 1 ATOM 1362 C C . GLN A 1 167 ? -2.409 -8.316 -39.563 1.00 331.77 ? 883 GLN A C 1 ATOM 1363 O O . GLN A 1 167 ? -2.221 -9.154 -38.673 1.00 333.10 ? 883 GLN A O 1 ATOM 1364 C CB . GLN A 1 167 ? -4.493 -6.984 -39.121 1.00 329.82 ? 883 GLN A CB 1 ATOM 1365 C CG . GLN A 1 167 ? -5.030 -7.521 -37.809 1.00 335.27 ? 883 GLN A CG 1 ATOM 1366 C CD . GLN A 1 167 ? -6.334 -6.858 -37.408 1.00 339.09 ? 883 GLN A CD 1 ATOM 1367 O OE1 . GLN A 1 167 ? -6.338 -5.746 -36.880 1.00 342.57 ? 883 GLN A OE1 1 ATOM 1368 N NE2 . GLN A 1 167 ? -7.448 -7.534 -37.663 1.00 340.82 ? 883 GLN A NE2 1 ATOM 1369 N N . LYS A 1 168 ? -2.134 -8.565 -40.843 1.00 330.97 ? 884 LYS A N 1 ATOM 1370 C CA . LYS A 1 168 ? -1.539 -9.836 -41.240 1.00 338.50 ? 884 LYS A CA 1 ATOM 1371 C C . LYS A 1 168 ? -0.064 -9.887 -40.862 1.00 336.46 ? 884 LYS A C 1 ATOM 1372 O O . LYS A 1 168 ? 0.397 -10.851 -40.239 1.00 337.39 ? 884 LYS A O 1 ATOM 1373 C CB . LYS A 1 168 ? -1.717 -10.048 -42.746 1.00 346.45 ? 884 LYS A CB 1 ATOM 1374 C CG . LYS A 1 168 ? -1.425 -11.461 -43.229 1.00 353.42 ? 884 LYS A CG 1 ATOM 1375 C CD . LYS A 1 168 ? -2.541 -12.417 -42.840 1.00 357.04 ? 884 LYS A CD 1 ATOM 1376 C CE . LYS A 1 168 ? -2.983 -13.270 -44.023 1.00 360.13 ? 884 LYS A CE 1 ATOM 1377 N NZ . LYS A 1 168 ? -1.922 -14.210 -44.478 1.00 363.22 ? 884 LYS A NZ 1 ATOM 1378 N N . GLU A 1 169 ? 0.687 -8.844 -41.215 1.00 340.21 ? 885 GLU A N 1 ATOM 1379 C CA . GLU A 1 169 ? 2.130 -8.831 -41.020 1.00 340.04 ? 885 GLU A CA 1 ATOM 1380 C C . GLU A 1 169 ? 2.544 -8.532 -39.584 1.00 339.71 ? 885 GLU A C 1 ATOM 1381 O O . GLU A 1 169 ? 3.725 -8.693 -39.258 1.00 337.19 ? 885 GLU A O 1 ATOM 1382 C CB . GLU A 1 169 ? 2.771 -7.815 -41.971 1.00 339.67 ? 885 GLU A CB 1 ATOM 1383 C CG . GLU A 1 169 ? 2.513 -8.110 -43.444 1.00 342.23 ? 885 GLU A CG 1 ATOM 1384 C CD . GLU A 1 169 ? 3.046 -7.029 -44.363 1.00 343.57 ? 885 GLU A CD 1 ATOM 1385 O OE1 . GLU A 1 169 ? 3.987 -6.314 -43.960 1.00 343.90 ? 885 GLU A OE1 1 ATOM 1386 O OE2 . GLU A 1 169 ? 2.520 -6.890 -45.488 1.00 341.05 ? 885 GLU A OE2 1 ATOM 1387 N N . THR A 1 170 ? 1.621 -8.107 -38.724 1.00 332.15 ? 886 THR A N 1 ATOM 1388 C CA . THR A 1 170 ? 1.959 -7.913 -37.320 1.00 334.52 ? 886 THR A CA 1 ATOM 1389 C C . THR A 1 170 ? 1.653 -9.142 -36.472 1.00 338.81 ? 886 THR A C 1 ATOM 1390 O O . THR A 1 170 ? 2.304 -9.352 -35.443 1.00 344.93 ? 886 THR A O 1 ATOM 1391 C CB . THR A 1 170 ? 1.226 -6.691 -36.749 1.00 336.67 ? 886 THR A CB 1 ATOM 1392 O OG1 . THR A 1 170 ? 1.812 -6.325 -35.493 1.00 339.72 ? 886 THR A OG1 1 ATOM 1393 C CG2 . THR A 1 170 ? -0.253 -6.986 -36.537 1.00 339.03 ? 886 THR A CG2 1 ATOM 1394 N N . THR A 1 171 ? 0.694 -9.964 -36.891 1.00 327.87 ? 887 THR A N 1 ATOM 1395 C CA . THR A 1 171 ? 0.355 -11.188 -36.173 1.00 330.80 ? 887 THR A CA 1 ATOM 1396 C C . THR A 1 171 ? 0.217 -12.359 -37.139 1.00 328.26 ? 887 THR A C 1 ATOM 1397 O O . THR A 1 171 ? 1.170 -13.105 -37.363 1.00 326.26 ? 887 THR A O 1 ATOM 1398 C CB . THR A 1 171 ? -0.954 -11.040 -35.372 1.00 336.21 ? 887 THR A CB 1 ATOM 1399 O OG1 . THR A 1 171 ? -1.962 -10.446 -36.199 1.00 338.96 ? 887 THR A OG1 1 ATOM 1400 C CG2 . THR A 1 171 ? -0.736 -10.180 -34.136 1.00 336.53 ? 887 THR A CG2 1 ATOM 1401 N N . SER A 1 181 ? 3.032 -5.858 -31.781 1.00 335.29 ? 897 SER A N 1 ATOM 1402 C CA . SER A 1 181 ? 4.414 -5.420 -31.620 1.00 334.70 ? 897 SER A CA 1 ATOM 1403 C C . SER A 1 181 ? 4.586 -3.967 -32.047 1.00 333.19 ? 897 SER A C 1 ATOM 1404 O O . SER A 1 181 ? 5.309 -3.201 -31.409 1.00 335.60 ? 897 SER A O 1 ATOM 1405 C CB . SER A 1 181 ? 5.357 -6.313 -32.430 1.00 332.85 ? 897 SER A CB 1 ATOM 1406 O OG . SER A 1 181 ? 5.097 -6.198 -33.820 1.00 328.25 ? 897 SER A OG 1 ATOM 1407 N N . MET A 1 182 ? 3.906 -3.593 -33.128 1.00 352.32 ? 898 MET A N 1 ATOM 1408 C CA . MET A 1 182 ? 4.099 -2.311 -33.777 1.00 346.49 ? 898 MET A CA 1 ATOM 1409 C C . MET A 1 182 ? 2.777 -1.563 -33.876 1.00 340.18 ? 898 MET A C 1 ATOM 1410 O O . MET A 1 182 ? 1.771 -2.150 -34.303 1.00 337.58 ? 898 MET A O 1 ATOM 1411 C CB . MET A 1 182 ? 4.688 -2.516 -35.181 1.00 346.61 ? 898 MET A CB 1 ATOM 1412 C CG . MET A 1 182 ? 5.290 -1.278 -35.814 1.00 348.38 ? 898 MET A CG 1 ATOM 1413 S SD . MET A 1 182 ? 5.866 -1.634 -37.486 1.00 350.84 ? 898 MET A SD 1 ATOM 1414 C CE . MET A 1 182 ? 7.010 -0.283 -37.748 1.00 354.36 ? 898 MET A CE 1 ATOM 1415 N N . PRO A 1 183 ? 2.726 -0.290 -33.489 1.00 339.68 ? 899 PRO A N 1 ATOM 1416 C CA . PRO A 1 183 ? 1.504 0.494 -33.701 1.00 338.72 ? 899 PRO A CA 1 ATOM 1417 C C . PRO A 1 183 ? 1.198 0.651 -35.183 1.00 338.41 ? 899 PRO A C 1 ATOM 1418 O O . PRO A 1 183 ? 2.070 0.528 -36.044 1.00 339.97 ? 899 PRO A O 1 ATOM 1419 C CB . PRO A 1 183 ? 1.827 1.845 -33.050 1.00 339.24 ? 899 PRO A CB 1 ATOM 1420 C CG . PRO A 1 183 ? 2.900 1.541 -32.061 1.00 342.60 ? 899 PRO A CG 1 ATOM 1421 C CD . PRO A 1 183 ? 3.711 0.431 -32.665 1.00 342.87 ? 899 PRO A CD 1 ATOM 1422 N N . PHE A 1 184 ? -0.074 0.936 -35.470 1.00 343.29 ? 900 PHE A N 1 ATOM 1423 C CA . PHE A 1 184 ? -0.517 1.045 -36.857 1.00 338.07 ? 900 PHE A CA 1 ATOM 1424 C C . PHE A 1 184 ? 0.129 2.234 -37.558 1.00 333.43 ? 900 PHE A C 1 ATOM 1425 O O . PHE A 1 184 ? 0.438 2.165 -38.754 1.00 333.00 ? 900 PHE A O 1 ATOM 1426 C CB . PHE A 1 184 ? -2.042 1.148 -36.908 1.00 337.18 ? 900 PHE A CB 1 ATOM 1427 C CG . PHE A 1 184 ? -2.598 1.319 -38.295 1.00 333.01 ? 900 PHE A CG 1 ATOM 1428 C CD1 . PHE A 1 184 ? -2.200 0.483 -39.326 1.00 331.88 ? 900 PHE A CD1 1 ATOM 1429 C CD2 . PHE A 1 184 ? -3.537 2.302 -38.562 1.00 331.51 ? 900 PHE A CD2 1 ATOM 1430 C CE1 . PHE A 1 184 ? -2.715 0.638 -40.601 1.00 331.39 ? 900 PHE A CE1 1 ATOM 1431 C CE2 . PHE A 1 184 ? -4.057 2.460 -39.833 1.00 330.83 ? 900 PHE A CE2 1 ATOM 1432 C CZ . PHE A 1 184 ? -3.646 1.625 -40.854 1.00 330.24 ? 900 PHE A CZ 1 ATOM 1433 N N . ILE A 1 185 ? 0.352 3.330 -36.829 1.00 337.34 ? 901 ILE A N 1 ATOM 1434 C CA . ILE A 1 185 ? 0.859 4.541 -37.466 1.00 338.04 ? 901 ILE A CA 1 ATOM 1435 C C . ILE A 1 185 ? 2.343 4.402 -37.791 1.00 338.74 ? 901 ILE A C 1 ATOM 1436 O O . ILE A 1 185 ? 2.819 4.927 -38.804 1.00 340.11 ? 901 ILE A O 1 ATOM 1437 C CB . ILE A 1 185 ? 0.577 5.771 -36.582 1.00 337.93 ? 901 ILE A CB 1 ATOM 1438 C CG1 . ILE A 1 185 ? 0.927 7.060 -37.329 1.00 339.68 ? 901 ILE A CG1 1 ATOM 1439 C CG2 . ILE A 1 185 ? 1.333 5.683 -35.264 1.00 339.12 ? 901 ILE A CG2 1 ATOM 1440 C CD1 . ILE A 1 185 ? 0.427 8.310 -36.646 1.00 341.55 ? 901 ILE A CD1 1 ATOM 1441 N N . THR A 1 186 ? 3.096 3.690 -36.949 1.00 337.72 ? 902 THR A N 1 ATOM 1442 C CA . THR A 1 186 ? 4.515 3.494 -37.226 1.00 341.22 ? 902 THR A CA 1 ATOM 1443 C C . THR A 1 186 ? 4.728 2.495 -38.354 1.00 340.21 ? 902 THR A C 1 ATOM 1444 O O . THR A 1 186 ? 5.719 2.593 -39.086 1.00 343.03 ? 902 THR A O 1 ATOM 1445 C CB . THR A 1 186 ? 5.251 3.040 -35.965 1.00 342.09 ? 902 THR A CB 1 ATOM 1446 O OG1 . THR A 1 186 ? 4.538 1.959 -35.360 1.00 345.15 ? 902 THR A OG1 1 ATOM 1447 C CG2 . THR A 1 186 ? 5.372 4.191 -34.975 1.00 342.67 ? 902 THR A CG2 1 ATOM 1448 N N . TYR A 1 187 ? 3.818 1.532 -38.508 1.00 338.84 ? 903 TYR A N 1 ATOM 1449 C CA . TYR A 1 187 ? 3.871 0.645 -39.666 1.00 340.43 ? 903 TYR A CA 1 ATOM 1450 C C . TYR A 1 187 ? 3.623 1.419 -40.953 1.00 341.12 ? 903 TYR A C 1 ATOM 1451 O O . TYR A 1 187 ? 4.270 1.164 -41.976 1.00 344.97 ? 903 TYR A O 1 ATOM 1452 C CB . TYR A 1 187 ? 2.852 -0.483 -39.508 1.00 340.12 ? 903 TYR A CB 1 ATOM 1453 C CG . TYR A 1 187 ? 2.592 -1.274 -40.771 1.00 343.62 ? 903 TYR A CG 1 ATOM 1454 C CD1 . TYR A 1 187 ? 3.459 -2.280 -41.175 1.00 345.25 ? 903 TYR A CD1 1 ATOM 1455 C CD2 . TYR A 1 187 ? 1.469 -1.023 -41.551 1.00 348.22 ? 903 TYR A CD2 1 ATOM 1456 C CE1 . TYR A 1 187 ? 3.220 -3.009 -42.326 1.00 349.03 ? 903 TYR A CE1 1 ATOM 1457 C CE2 . TYR A 1 187 ? 1.222 -1.746 -42.703 1.00 349.82 ? 903 TYR A CE2 1 ATOM 1458 C CZ . TYR A 1 187 ? 2.098 -2.739 -43.084 1.00 350.74 ? 903 TYR A CZ 1 ATOM 1459 O OH . TYR A 1 187 ? 1.857 -3.461 -44.231 1.00 353.09 ? 903 TYR A OH 1 ATOM 1460 N N . LEU A 1 188 ? 2.684 2.366 -40.920 1.00 348.30 ? 904 LEU A N 1 ATOM 1461 C CA . LEU A 1 188 ? 2.439 3.205 -42.086 1.00 346.76 ? 904 LEU A CA 1 ATOM 1462 C C . LEU A 1 188 ? 3.608 4.145 -42.336 1.00 348.56 ? 904 LEU A C 1 ATOM 1463 O O . LEU A 1 188 ? 4.063 4.297 -43.474 1.00 347.36 ? 904 LEU A O 1 ATOM 1464 C CB . LEU A 1 188 ? 1.142 3.997 -41.908 1.00 346.03 ? 904 LEU A CB 1 ATOM 1465 C CG . LEU A 1 188 ? -0.168 3.210 -41.967 1.00 345.03 ? 904 LEU A CG 1 ATOM 1466 C CD1 . LEU A 1 188 ? -1.355 4.134 -41.744 1.00 345.39 ? 904 LEU A CD1 1 ATOM 1467 C CD2 . LEU A 1 188 ? -0.289 2.488 -43.297 1.00 344.91 ? 904 LEU A CD2 1 ATOM 1468 N N . SER A 1 189 ? 4.112 4.783 -41.276 1.00 341.15 ? 905 SER A N 1 ATOM 1469 C CA . SER A 1 189 ? 5.270 5.657 -41.427 1.00 342.41 ? 905 SER A CA 1 ATOM 1470 C C . SER A 1 189 ? 6.488 4.884 -41.915 1.00 342.35 ? 905 SER A C 1 ATOM 1471 O O . SER A 1 189 ? 7.297 5.421 -42.678 1.00 345.15 ? 905 SER A O 1 ATOM 1472 C CB . SER A 1 189 ? 5.582 6.359 -40.104 1.00 342.08 ? 905 SER A CB 1 ATOM 1473 O OG . SER A 1 189 ? 6.208 5.471 -39.195 1.00 338.55 ? 905 SER A OG 1 ATOM 1474 N N . GLY A 1 190 ? 6.631 3.626 -41.501 1.00 335.86 ? 906 GLY A N 1 ATOM 1475 C CA . GLY A 1 190 ? 7.733 2.819 -41.998 1.00 342.14 ? 906 GLY A CA 1 ATOM 1476 C C . GLY A 1 190 ? 7.658 2.599 -43.495 1.00 345.21 ? 906 GLY A C 1 ATOM 1477 O O . GLY A 1 190 ? 8.670 2.672 -44.195 1.00 350.94 ? 906 GLY A O 1 ATOM 1478 N N . LEU A 1 191 ? 6.455 2.342 -44.008 1.00 346.45 ? 907 LEU A N 1 ATOM 1479 C CA . LEU A 1 191 ? 6.280 2.155 -45.440 1.00 345.59 ? 907 LEU A CA 1 ATOM 1480 C C . LEU A 1 191 ? 6.211 3.475 -46.193 1.00 343.31 ? 907 LEU A C 1 ATOM 1481 O O . LEU A 1 191 ? 6.432 3.495 -47.409 1.00 343.39 ? 907 LEU A O 1 ATOM 1482 C CB . LEU A 1 191 ? 5.027 1.322 -45.708 1.00 344.59 ? 907 LEU A CB 1 ATOM 1483 C CG . LEU A 1 191 ? 5.117 -0.155 -45.314 1.00 347.69 ? 907 LEU A CG 1 ATOM 1484 C CD1 . LEU A 1 191 ? 3.750 -0.812 -45.297 1.00 344.60 ? 907 LEU A CD1 1 ATOM 1485 C CD2 . LEU A 1 191 ? 6.039 -0.885 -46.272 1.00 351.68 ? 907 LEU A CD2 1 ATOM 1486 N N . LEU A 1 192 ? 5.913 4.573 -45.499 1.00 344.02 ? 908 LEU A N 1 ATOM 1487 C CA . LEU A 1 192 ? 5.953 5.885 -46.136 1.00 345.57 ? 908 LEU A CA 1 ATOM 1488 C C . LEU A 1 192 ? 7.388 6.342 -46.362 1.00 344.51 ? 908 LEU A C 1 ATOM 1489 O O . LEU A 1 192 ? 7.725 6.839 -47.443 1.00 342.86 ? 908 LEU A O 1 ATOM 1490 C CB . LEU A 1 192 ? 5.196 6.913 -45.291 1.00 349.84 ? 908 LEU A CB 1 ATOM 1491 C CG . LEU A 1 192 ? 3.831 7.397 -45.782 1.00 350.12 ? 908 LEU A CG 1 ATOM 1492 C CD1 . LEU A 1 192 ? 2.763 6.360 -45.515 1.00 351.22 ? 908 LEU A CD1 1 ATOM 1493 C CD2 . LEU A 1 192 ? 3.457 8.716 -45.125 1.00 352.18 ? 908 LEU A CD2 1 ATOM 1494 N N . THR A 1 193 ? 8.248 6.177 -45.355 1.00 343.13 ? 909 THR A N 1 ATOM 1495 C CA . THR A 1 193 ? 9.630 6.629 -45.479 1.00 345.68 ? 909 THR A CA 1 ATOM 1496 C C . THR A 1 193 ? 10.419 5.742 -46.432 1.00 349.48 ? 909 THR A C 1 ATOM 1497 O O . THR A 1 193 ? 11.263 6.233 -47.191 1.00 351.01 ? 909 THR A O 1 ATOM 1498 C CB . THR A 1 193 ? 10.306 6.663 -44.107 1.00 346.53 ? 909 THR A CB 1 ATOM 1499 O OG1 . THR A 1 193 ? 10.363 5.338 -43.570 1.00 348.16 ? 909 THR A OG1 1 ATOM 1500 C CG2 . THR A 1 193 ? 9.534 7.559 -43.152 1.00 347.42 ? 909 THR A CG2 1 ATOM 1501 N N . ALA A 1 194 ? 10.157 4.435 -46.411 1.00 339.19 ? 910 ALA A N 1 ATOM 1502 C CA . ALA A 1 194 ? 10.866 3.512 -47.285 1.00 347.66 ? 910 ALA A CA 1 ATOM 1503 C C . ALA A 1 194 ? 10.430 3.624 -48.738 1.00 356.34 ? 910 ALA A C 1 ATOM 1504 O O . ALA A 1 194 ? 11.098 3.057 -49.611 1.00 356.48 ? 910 ALA A O 1 ATOM 1505 C CB . ALA A 1 194 ? 10.674 2.075 -46.800 1.00 349.33 ? 910 ALA A CB 1 ATOM 1506 N N . GLN A 1 195 ? 9.338 4.337 -49.018 1.00 338.76 ? 911 GLN A N 1 ATOM 1507 C CA . GLN A 1 195 ? 8.852 4.456 -50.386 1.00 349.48 ? 911 GLN A CA 1 ATOM 1508 C C . GLN A 1 195 ? 9.787 5.268 -51.271 1.00 357.23 ? 911 GLN A C 1 ATOM 1509 O O . GLN A 1 195 ? 9.598 5.281 -52.491 1.00 357.79 ? 911 GLN A O 1 ATOM 1510 C CB . GLN A 1 195 ? 7.448 5.067 -50.399 1.00 353.17 ? 911 GLN A CB 1 ATOM 1511 C CG . GLN A 1 195 ? 6.641 4.744 -51.652 1.00 358.87 ? 911 GLN A CG 1 ATOM 1512 C CD . GLN A 1 195 ? 5.232 5.305 -51.608 1.00 365.34 ? 911 GLN A CD 1 ATOM 1513 O OE1 . GLN A 1 195 ? 4.882 6.068 -50.708 1.00 373.17 ? 911 GLN A OE1 1 ATOM 1514 N NE2 . GLN A 1 195 ? 4.414 4.924 -52.583 1.00 366.92 ? 911 GLN A NE2 1 ATOM 1515 N N . MET A 1 196 ? 10.785 5.938 -50.693 1.00 352.24 ? 912 MET A N 1 ATOM 1516 C CA . MET A 1 196 ? 11.825 6.549 -51.511 1.00 356.30 ? 912 MET A CA 1 ATOM 1517 C C . MET A 1 196 ? 12.605 5.506 -52.299 1.00 358.67 ? 912 MET A C 1 ATOM 1518 O O . MET A 1 196 ? 13.295 5.857 -53.263 1.00 355.62 ? 912 MET A O 1 ATOM 1519 C CB . MET A 1 196 ? 12.777 7.373 -50.637 1.00 356.49 ? 912 MET A CB 1 ATOM 1520 C CG . MET A 1 196 ? 12.141 8.615 -50.028 1.00 356.93 ? 912 MET A CG 1 ATOM 1521 S SD . MET A 1 196 ? 13.317 9.668 -49.153 1.00 359.93 ? 912 MET A SD 1 ATOM 1522 C CE . MET A 1 196 ? 13.906 8.555 -47.878 1.00 357.60 ? 912 MET A CE 1 ATOM 1523 N N . LEU A 1 197 ? 12.505 4.235 -51.912 1.00 361.52 ? 913 LEU A N 1 ATOM 1524 C CA . LEU A 1 197 ? 13.130 3.158 -52.668 1.00 361.61 ? 913 LEU A CA 1 ATOM 1525 C C . LEU A 1 197 ? 12.291 2.766 -53.879 1.00 362.29 ? 913 LEU A C 1 ATOM 1526 O O . LEU A 1 197 ? 12.839 2.457 -54.944 1.00 360.39 ? 913 LEU A O 1 ATOM 1527 C CB . LEU A 1 197 ? 13.349 1.943 -51.765 1.00 359.80 ? 913 LEU A CB 1 ATOM 1528 C CG . LEU A 1 197 ? 14.188 2.139 -50.500 1.00 356.98 ? 913 LEU A CG 1 ATOM 1529 C CD1 . LEU A 1 197 ? 14.093 0.916 -49.600 1.00 354.14 ? 913 LEU A CD1 1 ATOM 1530 C CD2 . LEU A 1 197 ? 15.634 2.424 -50.864 1.00 355.57 ? 913 LEU A CD2 1 ATOM 1531 N N . SER A 1 198 ? 10.967 2.775 -53.737 1.00 361.33 ? 914 SER A N 1 ATOM 1532 C CA . SER A 1 198 ? 10.041 2.323 -54.760 1.00 363.79 ? 914 SER A CA 1 ATOM 1533 C C . SER A 1 198 ? 9.243 3.520 -55.289 1.00 363.21 ? 914 SER A C 1 ATOM 1534 O O . SER A 1 198 ? 9.743 4.658 -55.265 1.00 361.56 ? 914 SER A O 1 ATOM 1535 C CB . SER A 1 198 ? 9.169 1.212 -54.179 1.00 362.13 ? 914 SER A CB 1 ATOM 1536 O OG . SER A 1 198 ? 8.204 1.734 -53.282 1.00 360.41 ? 914 SER A OG 1 ATOM 1537 N N . ASP A 1 199 ? 8.023 3.271 -55.766 1.00 368.53 ? 915 ASP A N 1 ATOM 1538 C CA . ASP A 1 199 ? 7.162 4.340 -56.261 1.00 366.18 ? 915 ASP A CA 1 ATOM 1539 C C . ASP A 1 199 ? 5.699 4.062 -55.933 1.00 361.61 ? 915 ASP A C 1 ATOM 1540 O O . ASP A 1 199 ? 5.328 3.980 -54.758 1.00 355.98 ? 915 ASP A O 1 ATOM 1541 C CB . ASP A 1 199 ? 7.348 4.528 -57.770 1.00 368.06 ? 915 ASP A CB 1 ATOM 1542 C CG . ASP A 1 199 ? 6.936 5.914 -58.241 1.00 365.80 ? 915 ASP A CG 1 ATOM 1543 O OD1 . ASP A 1 199 ? 6.216 6.612 -57.495 1.00 365.49 ? 915 ASP A OD1 1 ATOM 1544 O OD2 . ASP A 1 199 ? 7.333 6.306 -59.359 1.00 361.07 ? 915 ASP A OD2 1 ATOM 1545 N N . ASP A 1 200 ? 4.866 3.908 -56.960 1.00 360.50 ? 916 ASP A N 1 ATOM 1546 C CA . ASP A 1 200 ? 3.429 3.777 -56.748 1.00 359.02 ? 916 ASP A CA 1 ATOM 1547 C C . ASP A 1 200 ? 3.069 2.424 -56.146 1.00 358.84 ? 916 ASP A C 1 ATOM 1548 O O . ASP A 1 200 ? 3.593 1.382 -56.553 1.00 365.36 ? 916 ASP A O 1 ATOM 1549 C CB . ASP A 1 200 ? 2.672 3.973 -58.060 1.00 356.72 ? 916 ASP A CB 1 ATOM 1550 C CG . ASP A 1 200 ? 2.555 5.431 -58.452 1.00 357.19 ? 916 ASP A CG 1 ATOM 1551 O OD1 . ASP A 1 200 ? 3.406 6.236 -58.021 1.00 353.01 ? 916 ASP A OD1 1 ATOM 1552 O OD2 . ASP A 1 200 ? 1.611 5.772 -59.194 1.00 363.79 ? 916 ASP A OD2 1 ATOM 1553 N N . GLN A 1 201 ? 2.149 2.453 -55.184 1.00 360.09 ? 917 GLN A N 1 ATOM 1554 C CA . GLN A 1 201 ? 1.663 1.261 -54.495 1.00 352.13 ? 917 GLN A CA 1 ATOM 1555 C C . GLN A 1 201 ? 0.357 1.624 -53.790 1.00 343.15 ? 917 GLN A C 1 ATOM 1556 O O . GLN A 1 201 ? -0.179 2.723 -53.968 1.00 343.69 ? 917 GLN A O 1 ATOM 1557 C CB . GLN A 1 201 ? 2.741 0.729 -53.538 1.00 353.52 ? 917 GLN A CB 1 ATOM 1558 C CG . GLN A 1 201 ? 2.629 -0.755 -53.208 1.00 358.22 ? 917 GLN A CG 1 ATOM 1559 C CD . GLN A 1 201 ? 3.888 -1.315 -52.565 1.00 362.66 ? 917 GLN A CD 1 ATOM 1560 O OE1 . GLN A 1 201 ? 5.005 -0.911 -52.896 1.00 365.55 ? 917 GLN A OE1 1 ATOM 1561 N NE2 . GLN A 1 201 ? 3.712 -2.254 -51.644 1.00 365.26 ? 917 GLN A NE2 1 ATOM 1562 N N . LEU A 1 202 ? -0.163 0.685 -52.990 1.00 350.97 ? 918 LEU A N 1 ATOM 1563 C CA . LEU A 1 202 ? -1.372 0.897 -52.187 1.00 340.83 ? 918 LEU A CA 1 ATOM 1564 C C . LEU A 1 202 ? -1.235 2.085 -51.234 1.00 338.66 ? 918 LEU A C 1 ATOM 1565 O O . LEU A 1 202 ? -2.247 2.673 -50.834 1.00 336.85 ? 918 LEU A O 1 ATOM 1566 C CB . LEU A 1 202 ? -1.684 -0.396 -51.414 1.00 332.81 ? 918 LEU A CB 1 ATOM 1567 C CG . LEU A 1 202 ? -2.865 -0.438 -50.459 1.00 328.53 ? 918 LEU A CG 1 ATOM 1568 C CD1 . LEU A 1 202 ? -4.158 -0.187 -51.213 1.00 331.50 ? 918 LEU A CD1 1 ATOM 1569 C CD2 . LEU A 1 202 ? -2.889 -1.786 -49.772 1.00 324.87 ? 918 LEU A CD2 1 ATOM 1570 N N . ILE A 1 203 ? -0.007 2.482 -50.909 1.00 335.39 ? 919 ILE A N 1 ATOM 1571 C CA . ILE A 1 203 ? 0.280 3.558 -49.961 1.00 333.15 ? 919 ILE A CA 1 ATOM 1572 C C . ILE A 1 203 ? 0.520 4.898 -50.669 1.00 328.73 ? 919 ILE A C 1 ATOM 1573 O O . ILE A 1 203 ? 0.866 5.880 -50.018 1.00 329.99 ? 919 ILE A O 1 ATOM 1574 C CB . ILE A 1 203 ? 1.459 3.128 -49.060 1.00 337.95 ? 919 ILE A CB 1 ATOM 1575 C CG1 . ILE A 1 203 ? 1.086 1.807 -48.408 1.00 346.37 ? 919 ILE A CG1 1 ATOM 1576 C CG2 . ILE A 1 203 ? 1.796 4.151 -47.971 1.00 336.08 ? 919 ILE A CG2 1 ATOM 1577 C CD1 . ILE A 1 203 ? 1.925 1.417 -47.281 1.00 349.29 ? 919 ILE A CD1 1 ATOM 1578 N N . SER A 1 204 ? 0.285 4.974 -51.991 1.00 336.37 ? 920 SER A N 1 ATOM 1579 C CA . SER A 1 204 ? 0.514 6.197 -52.770 1.00 334.73 ? 920 SER A CA 1 ATOM 1580 C C . SER A 1 204 ? 0.147 7.507 -52.060 1.00 328.86 ? 920 SER A C 1 ATOM 1581 O O . SER A 1 204 ? 1.007 8.373 -51.859 1.00 331.87 ? 920 SER A O 1 ATOM 1582 C CB . SER A 1 204 ? -0.255 6.102 -54.103 1.00 339.25 ? 920 SER A CB 1 ATOM 1583 O OG . SER A 1 204 ? -0.178 7.279 -54.893 1.00 342.23 ? 920 SER A OG 1 ATOM 1584 N N . GLY A 1 205 ? -1.131 7.698 -51.729 1.00 330.81 ? 921 GLY A N 1 ATOM 1585 C CA . GLY A 1 205 ? -1.637 8.974 -51.253 1.00 327.57 ? 921 GLY A CA 1 ATOM 1586 C C . GLY A 1 205 ? -1.792 9.144 -49.754 1.00 324.65 ? 921 GLY A C 1 ATOM 1587 O O . GLY A 1 205 ? -2.445 10.105 -49.325 1.00 321.20 ? 921 GLY A O 1 ATOM 1588 N N . VAL A 1 206 ? -1.211 8.258 -48.939 1.00 329.11 ? 922 VAL A N 1 ATOM 1589 C CA . VAL A 1 206 ? -1.342 8.364 -47.488 1.00 325.47 ? 922 VAL A CA 1 ATOM 1590 C C . VAL A 1 206 ? -0.435 9.474 -46.971 1.00 325.51 ? 922 VAL A C 1 ATOM 1591 O O . VAL A 1 206 ? 0.713 9.617 -47.409 1.00 326.16 ? 922 VAL A O 1 ATOM 1592 C CB . VAL A 1 206 ? -1.016 7.018 -46.814 1.00 325.06 ? 922 VAL A CB 1 ATOM 1593 C CG1 . VAL A 1 206 ? -1.130 7.134 -45.295 1.00 326.79 ? 922 VAL A CG1 1 ATOM 1594 C CG2 . VAL A 1 206 ? -1.936 5.925 -47.331 1.00 325.01 ? 922 VAL A CG2 1 ATOM 1595 N N . GLU A 1 207 ? -0.956 10.273 -46.038 1.00 318.92 ? 923 GLU A N 1 ATOM 1596 C CA . GLU A 1 207 ? -0.197 11.347 -45.411 1.00 320.77 ? 923 GLU A CA 1 ATOM 1597 C C . GLU A 1 207 ? -0.486 11.370 -43.918 1.00 314.19 ? 923 GLU A C 1 ATOM 1598 O O . GLU A 1 207 ? -1.619 11.124 -43.494 1.00 314.31 ? 923 GLU A O 1 ATOM 1599 C CB . GLU A 1 207 ? -0.535 12.713 -46.026 1.00 330.57 ? 923 GLU A CB 1 ATOM 1600 C CG . GLU A 1 207 ? -0.219 12.834 -47.507 1.00 341.18 ? 923 GLU A CG 1 ATOM 1601 C CD . GLU A 1 207 ? 0.462 14.144 -47.850 1.00 350.07 ? 923 GLU A CD 1 ATOM 1602 O OE1 . GLU A 1 207 ? 1.467 14.482 -47.189 1.00 356.63 ? 923 GLU A OE1 1 ATOM 1603 O OE2 . GLU A 1 207 ? -0.010 14.837 -48.775 1.00 355.46 ? 923 GLU A OE2 1 ATOM 1604 N N . ILE A 1 208 ? 0.541 11.672 -43.127 1.00 322.37 ? 924 ILE A N 1 ATOM 1605 C CA . ILE A 1 208 ? 0.438 11.748 -41.674 1.00 316.84 ? 924 ILE A CA 1 ATOM 1606 C C . ILE A 1 208 ? 0.796 13.163 -41.240 1.00 320.49 ? 924 ILE A C 1 ATOM 1607 O O . ILE A 1 208 ? 1.798 13.724 -41.698 1.00 323.07 ? 924 ILE A O 1 ATOM 1608 C CB . ILE A 1 208 ? 1.351 10.716 -40.983 1.00 313.90 ? 924 ILE A CB 1 ATOM 1609 C CG1 . ILE A 1 208 ? 1.016 9.301 -41.462 1.00 316.20 ? 924 ILE A CG1 1 ATOM 1610 C CG2 . ILE A 1 208 ? 1.225 10.812 -39.470 1.00 312.81 ? 924 ILE A CG2 1 ATOM 1611 C CD1 . ILE A 1 208 ? 1.906 8.227 -40.871 1.00 317.03 ? 924 ILE A CD1 1 ATOM 1612 N N . ARG A 1 209 ? -0.026 13.738 -40.364 1.00 313.62 ? 925 ARG A N 1 ATOM 1613 C CA . ARG A 1 209 ? 0.177 15.092 -39.857 1.00 316.76 ? 925 ARG A CA 1 ATOM 1614 C C . ARG A 1 209 ? 0.023 15.072 -38.345 1.00 315.88 ? 925 ARG A C 1 ATOM 1615 O O . ARG A 1 209 ? -1.042 14.713 -37.833 1.00 316.97 ? 925 ARG A O 1 ATOM 1616 C CB . ARG A 1 209 ? -0.815 16.070 -40.492 1.00 321.14 ? 925 ARG A CB 1 ATOM 1617 C CG . ARG A 1 209 ? -0.652 16.220 -41.997 1.00 329.14 ? 925 ARG A CG 1 ATOM 1618 C CD . ARG A 1 209 ? 0.629 16.962 -42.338 1.00 338.84 ? 925 ARG A CD 1 ATOM 1619 N NE . ARG A 1 209 ? 1.167 16.566 -43.637 1.00 350.02 ? 925 ARG A NE 1 ATOM 1620 C CZ . ARG A 1 209 ? 0.794 17.096 -44.796 1.00 356.44 ? 925 ARG A CZ 1 ATOM 1621 N NH1 . ARG A 1 209 ? -0.129 18.048 -44.825 1.00 358.73 ? 925 ARG A NH1 1 ATOM 1622 N NH2 . ARG A 1 209 ? 1.342 16.673 -45.927 1.00 355.36 ? 925 ARG A NH2 1 ATOM 1623 N N . CYS A 1 210 ? 1.077 15.464 -37.634 1.00 326.30 ? 926 CYS A N 1 ATOM 1624 C CA . CYS A 1 210 ? 1.104 15.420 -36.181 1.00 326.45 ? 926 CYS A CA 1 ATOM 1625 C C . CYS A 1 210 ? 1.203 16.822 -35.595 1.00 323.35 ? 926 CYS A C 1 ATOM 1626 O O . CYS A 1 210 ? 1.740 17.741 -36.220 1.00 323.34 ? 926 CYS A O 1 ATOM 1627 C CB . CYS A 1 210 ? 2.277 14.572 -35.679 1.00 329.94 ? 926 CYS A CB 1 ATOM 1628 S SG . CYS A 1 210 ? 2.224 12.833 -36.161 1.00 337.41 ? 926 CYS A SG 1 ATOM 1629 N N . GLU A 1 211 ? 0.672 16.971 -34.383 1.00 310.90 ? 927 GLU A N 1 ATOM 1630 C CA . GLU A 1 211 ? 0.777 18.201 -33.608 1.00 313.67 ? 927 GLU A CA 1 ATOM 1631 C C . GLU A 1 211 ? 0.962 17.831 -32.146 1.00 313.22 ? 927 GLU A C 1 ATOM 1632 O O . GLU A 1 211 ? 0.203 17.018 -31.609 1.00 313.84 ? 927 GLU A O 1 ATOM 1633 C CB . GLU A 1 211 ? -0.460 19.087 -33.780 1.00 315.79 ? 927 GLU A CB 1 ATOM 1634 C CG . GLU A 1 211 ? -0.489 19.864 -35.082 1.00 321.31 ? 927 GLU A CG 1 ATOM 1635 C CD . GLU A 1 211 ? -1.594 20.899 -35.114 1.00 328.39 ? 927 GLU A CD 1 ATOM 1636 O OE1 . GLU A 1 211 ? -2.594 20.726 -34.386 1.00 337.40 ? 927 GLU A OE1 1 ATOM 1637 O OE2 . GLU A 1 211 ? -1.458 21.891 -35.862 1.00 333.37 ? 927 GLU A OE2 1 ATOM 1638 N N . GLU A 1 212 ? 1.962 18.428 -31.505 1.00 314.13 ? 928 GLU A N 1 ATOM 1639 C CA . GLU A 1 212 ? 2.381 18.039 -30.167 1.00 315.57 ? 928 GLU A CA 1 ATOM 1640 C C . GLU A 1 212 ? 2.126 19.172 -29.182 1.00 312.38 ? 928 GLU A C 1 ATOM 1641 O O . GLU A 1 212 ? 2.503 20.321 -29.436 1.00 311.00 ? 928 GLU A O 1 ATOM 1642 C CB . GLU A 1 212 ? 3.860 17.645 -30.164 1.00 321.64 ? 928 GLU A CB 1 ATOM 1643 C CG . GLU A 1 212 ? 4.325 16.940 -28.903 1.00 328.68 ? 928 GLU A CG 1 ATOM 1644 C CD . GLU A 1 212 ? 5.488 16.000 -29.159 1.00 334.70 ? 928 GLU A CD 1 ATOM 1645 O OE1 . GLU A 1 212 ? 5.358 14.795 -28.851 1.00 334.57 ? 928 GLU A OE1 1 ATOM 1646 O OE2 . GLU A 1 212 ? 6.526 16.460 -29.682 1.00 338.51 ? 928 GLU A OE2 1 ATOM 1647 N N . LYS A 1 213 ? 1.471 18.844 -28.071 1.00 322.61 ? 929 LYS A N 1 ATOM 1648 C CA . LYS A 1 213 ? 1.312 19.736 -26.926 1.00 323.32 ? 929 LYS A CA 1 ATOM 1649 C C . LYS A 1 213 ? 2.210 19.189 -25.822 1.00 322.65 ? 929 LYS A C 1 ATOM 1650 O O . LYS A 1 213 ? 1.873 18.192 -25.178 1.00 323.05 ? 929 LYS A O 1 ATOM 1651 C CB . LYS A 1 213 ? -0.142 19.808 -26.467 1.00 325.29 ? 929 LYS A CB 1 ATOM 1652 C CG . LYS A 1 213 ? -1.049 20.688 -27.307 1.00 327.81 ? 929 LYS A CG 1 ATOM 1653 C CD . LYS A 1 213 ? -2.458 20.677 -26.732 1.00 329.99 ? 929 LYS A CD 1 ATOM 1654 C CE . LYS A 1 213 ? -3.425 21.479 -27.580 1.00 337.15 ? 929 LYS A CE 1 ATOM 1655 N NZ . LYS A 1 213 ? -4.833 21.270 -27.140 1.00 342.34 ? 929 LYS A NZ 1 ATOM 1656 N N . GLY A 1 214 ? 3.350 19.839 -25.607 1.00 327.86 ? 930 GLY A N 1 ATOM 1657 C CA . GLY A 1 214 ? 4.319 19.331 -24.659 1.00 330.03 ? 930 GLY A CA 1 ATOM 1658 C C . GLY A 1 214 ? 5.148 18.214 -25.256 1.00 331.36 ? 930 GLY A C 1 ATOM 1659 O O . GLY A 1 214 ? 4.601 17.226 -25.756 1.00 332.45 ? 930 GLY A O 1 ATOM 1660 N N . ARG A 1 215 ? 6.467 18.358 -25.206 1.00 317.07 ? 931 ARG A N 1 ATOM 1661 C CA . ARG A 1 215 ? 7.346 17.428 -25.898 1.00 318.51 ? 931 ARG A CA 1 ATOM 1662 C C . ARG A 1 215 ? 7.313 16.043 -25.261 1.00 316.61 ? 931 ARG A C 1 ATOM 1663 O O . ARG A 1 215 ? 7.037 15.885 -24.068 1.00 309.38 ? 931 ARG A O 1 ATOM 1664 C CB . ARG A 1 215 ? 8.771 17.979 -25.928 1.00 323.23 ? 931 ARG A CB 1 ATOM 1665 C CG . ARG A 1 215 ? 8.918 19.200 -26.822 1.00 330.26 ? 931 ARG A CG 1 ATOM 1666 C CD . ARG A 1 215 ? 10.332 19.743 -26.812 1.00 339.31 ? 931 ARG A CD 1 ATOM 1667 N NE . ARG A 1 215 ? 10.617 20.517 -28.015 1.00 350.07 ? 931 ARG A NE 1 ATOM 1668 C CZ . ARG A 1 215 ? 11.115 19.993 -29.130 1.00 355.91 ? 931 ARG A CZ 1 ATOM 1669 N NH1 . ARG A 1 215 ? 11.383 18.696 -29.186 1.00 354.01 ? 931 ARG A NH1 1 ATOM 1670 N NH2 . ARG A 1 215 ? 11.347 20.761 -30.186 1.00 358.33 ? 931 ARG A NH2 1 ATOM 1671 N N . CYS A 1 216 ? 7.597 15.034 -26.083 1.00 336.85 ? 932 CYS A N 1 ATOM 1672 C CA . CYS A 1 216 ? 7.502 13.631 -25.686 1.00 338.60 ? 932 CYS A CA 1 ATOM 1673 C C . CYS A 1 216 ? 8.647 13.265 -24.747 1.00 339.11 ? 932 CYS A C 1 ATOM 1674 O O . CYS A 1 216 ? 9.811 13.526 -25.067 1.00 341.88 ? 932 CYS A O 1 ATOM 1675 C CB . CYS A 1 216 ? 7.524 12.728 -26.918 1.00 341.37 ? 932 CYS A CB 1 ATOM 1676 S SG . CYS A 1 216 ? 7.598 10.941 -26.605 1.00 343.52 ? 932 CYS A SG 1 ATOM 1677 N N . PRO A 1 217 ? 8.361 12.662 -23.597 1.00 341.03 ? 933 PRO A N 1 ATOM 1678 C CA . PRO A 1 217 ? 9.436 12.276 -22.678 1.00 340.86 ? 933 PRO A CA 1 ATOM 1679 C C . PRO A 1 217 ? 10.270 11.134 -23.236 1.00 344.58 ? 933 PRO A C 1 ATOM 1680 O O . PRO A 1 217 ? 9.830 10.361 -24.091 1.00 344.39 ? 933 PRO A O 1 ATOM 1681 C CB . PRO A 1 217 ? 8.684 11.852 -21.412 1.00 341.62 ? 933 PRO A CB 1 ATOM 1682 C CG . PRO A 1 217 ? 7.332 11.448 -21.898 1.00 342.13 ? 933 PRO A CG 1 ATOM 1683 C CD . PRO A 1 217 ? 7.027 12.352 -23.056 1.00 342.32 ? 933 PRO A CD 1 ATOM 1684 N N . SER A 1 218 ? 11.499 11.035 -22.724 1.00 350.02 ? 934 SER A N 1 ATOM 1685 C CA . SER A 1 218 ? 12.436 10.032 -23.222 1.00 353.78 ? 934 SER A CA 1 ATOM 1686 C C . SER A 1 218 ? 12.001 8.616 -22.864 1.00 356.26 ? 934 SER A C 1 ATOM 1687 O O . SER A 1 218 ? 12.311 7.670 -23.597 1.00 358.64 ? 934 SER A O 1 ATOM 1688 C CB . SER A 1 218 ? 13.837 10.314 -22.677 1.00 356.84 ? 934 SER A CB 1 ATOM 1689 O OG . SER A 1 218 ? 14.789 9.409 -23.211 1.00 365.33 ? 934 SER A OG 1 ATOM 1690 N N . THR A 1 219 ? 11.279 8.450 -21.755 1.00 351.41 ? 935 THR A N 1 ATOM 1691 C CA . THR A 1 219 ? 10.891 7.111 -21.318 1.00 353.44 ? 935 THR A CA 1 ATOM 1692 C C . THR A 1 219 ? 9.838 6.505 -22.239 1.00 353.45 ? 935 THR A C 1 ATOM 1693 O O . THR A 1 219 ? 9.914 5.318 -22.579 1.00 356.03 ? 935 THR A O 1 ATOM 1694 C CB . THR A 1 219 ? 10.377 7.156 -19.878 1.00 357.80 ? 935 THR A CB 1 ATOM 1695 O OG1 . THR A 1 219 ? 9.247 8.033 -19.800 1.00 361.73 ? 935 THR A OG1 1 ATOM 1696 C CG2 . THR A 1 219 ? 11.465 7.653 -18.938 1.00 360.28 ? 935 THR A CG2 1 ATOM 1697 N N . CYS A 1 220 ? 8.852 7.298 -22.651 1.00 359.37 ? 936 CYS A N 1 ATOM 1698 C CA . CYS A 1 220 ? 7.746 6.790 -23.453 1.00 357.00 ? 936 CYS A CA 1 ATOM 1699 C C . CYS A 1 220 ? 8.198 6.544 -24.887 1.00 355.74 ? 936 CYS A C 1 ATOM 1700 O O . CYS A 1 220 ? 8.826 7.407 -25.506 1.00 356.54 ? 936 CYS A O 1 ATOM 1701 C CB . CYS A 1 220 ? 6.578 7.776 -23.416 1.00 354.17 ? 936 CYS A CB 1 ATOM 1702 S SG . CYS A 1 220 ? 5.046 7.234 -24.226 1.00 353.87 ? 936 CYS A SG 1 ATOM 1703 N N . HIS A 1 221 ? 7.878 5.362 -25.415 1.00 347.74 ? 937 HIS A N 1 ATOM 1704 C CA . HIS A 1 221 ? 8.277 4.980 -26.763 1.00 353.34 ? 937 HIS A CA 1 ATOM 1705 C C . HIS A 1 221 ? 7.150 5.089 -27.784 1.00 351.14 ? 937 HIS A C 1 ATOM 1706 O O . HIS A 1 221 ? 7.390 4.856 -28.971 1.00 358.45 ? 937 HIS A O 1 ATOM 1707 C CB . HIS A 1 221 ? 8.824 3.546 -26.772 1.00 362.01 ? 937 HIS A CB 1 ATOM 1708 C CG . HIS A 1 221 ? 10.116 3.388 -26.032 1.00 371.85 ? 937 HIS A CG 1 ATOM 1709 N ND1 . HIS A 1 221 ? 11.301 3.936 -26.476 1.00 372.63 ? 937 HIS A ND1 1 ATOM 1710 C CD2 . HIS A 1 221 ? 10.413 2.736 -24.882 1.00 375.55 ? 937 HIS A CD2 1 ATOM 1711 C CE1 . HIS A 1 221 ? 12.269 3.634 -25.630 1.00 373.45 ? 937 HIS A CE1 1 ATOM 1712 N NE2 . HIS A 1 221 ? 11.757 2.905 -24.654 1.00 376.59 ? 937 HIS A NE2 1 ATOM 1713 N N . LEU A 1 222 ? 5.934 5.427 -27.357 1.00 351.40 ? 938 LEU A N 1 ATOM 1714 C CA . LEU A 1 222 ? 4.829 5.540 -28.300 1.00 344.39 ? 938 LEU A CA 1 ATOM 1715 C C . LEU A 1 222 ? 4.786 6.904 -28.971 1.00 344.46 ? 938 LEU A C 1 ATOM 1716 O O . LEU A 1 222 ? 4.368 7.007 -30.132 1.00 354.29 ? 938 LEU A O 1 ATOM 1717 C CB . LEU A 1 222 ? 3.497 5.259 -27.599 1.00 342.79 ? 938 LEU A CB 1 ATOM 1718 C CG . LEU A 1 222 ? 3.061 3.800 -27.450 1.00 341.18 ? 938 LEU A CG 1 ATOM 1719 C CD1 . LEU A 1 222 ? 1.690 3.721 -26.795 1.00 342.49 ? 938 LEU A CD1 1 ATOM 1720 C CD2 . LEU A 1 222 ? 3.043 3.122 -28.804 1.00 337.38 ? 938 LEU A CD2 1 ATOM 1721 N N . CYS A 1 223 ? 5.205 7.951 -28.269 1.00 341.53 ? 939 CYS A N 1 ATOM 1722 C CA . CYS A 1 223 ? 5.259 9.290 -28.835 1.00 339.87 ? 939 CYS A CA 1 ATOM 1723 C C . CYS A 1 223 ? 6.637 9.643 -29.365 1.00 335.81 ? 939 CYS A C 1 ATOM 1724 O O . CYS A 1 223 ? 6.851 10.787 -29.783 1.00 332.62 ? 939 CYS A O 1 ATOM 1725 C CB . CYS A 1 223 ? 4.803 10.332 -27.803 1.00 342.50 ? 939 CYS A CB 1 ATOM 1726 S SG . CYS A 1 223 ? 5.680 10.393 -26.202 1.00 350.64 ? 939 CYS A SG 1 ATOM 1727 N N . ARG A 1 224 ? 7.576 8.699 -29.349 1.00 330.29 ? 940 ARG A N 1 ATOM 1728 C CA . ARG A 1 224 ? 8.936 9.022 -29.751 1.00 335.86 ? 940 ARG A CA 1 ATOM 1729 C C . ARG A 1 224 ? 8.974 9.408 -31.217 1.00 335.45 ? 940 ARG A C 1 ATOM 1730 O O . ARG A 1 224 ? 8.520 8.663 -32.093 1.00 336.78 ? 940 ARG A O 1 ATOM 1731 C CB . ARG A 1 224 ? 9.899 7.862 -29.512 1.00 341.95 ? 940 ARG A CB 1 ATOM 1732 C CG . ARG A 1 224 ? 11.260 8.109 -30.173 1.00 350.10 ? 940 ARG A CG 1 ATOM 1733 C CD . ARG A 1 224 ? 12.394 7.448 -29.420 1.00 357.29 ? 940 ARG A CD 1 ATOM 1734 N NE . ARG A 1 224 ? 12.465 7.895 -28.033 1.00 363.02 ? 940 ARG A NE 1 ATOM 1735 C CZ . ARG A 1 224 ? 13.393 7.494 -27.172 1.00 368.91 ? 940 ARG A CZ 1 ATOM 1736 N NH1 . ARG A 1 224 ? 14.330 6.641 -27.561 1.00 371.09 ? 940 ARG A NH1 1 ATOM 1737 N NH2 . ARG A 1 224 ? 13.386 7.943 -25.924 1.00 372.67 ? 940 ARG A NH2 1 ATOM 1738 N N . ARG A 1 225 ? 9.511 10.585 -31.473 1.00 348.54 ? 941 ARG A N 1 ATOM 1739 C CA . ARG A 1 225 ? 9.759 11.063 -32.799 1.00 348.66 ? 941 ARG A CA 1 ATOM 1740 C C . ARG A 1 225 ? 11.262 11.255 -32.922 1.00 349.50 ? 941 ARG A C 1 ATOM 1741 O O . ARG A 1 225 ? 11.867 11.894 -32.050 1.00 353.47 ? 941 ARG A O 1 ATOM 1742 C CB . ARG A 1 225 ? 8.998 12.371 -33.039 1.00 349.15 ? 941 ARG A CB 1 ATOM 1743 C CG . ARG A 1 225 ? 7.491 12.206 -32.856 1.00 349.28 ? 941 ARG A CG 1 ATOM 1744 C CD . ARG A 1 225 ? 6.799 13.534 -32.636 1.00 351.07 ? 941 ARG A CD 1 ATOM 1745 N NE . ARG A 1 225 ? 6.640 14.304 -33.866 1.00 350.28 ? 941 ARG A NE 1 ATOM 1746 C CZ . ARG A 1 225 ? 6.338 15.597 -33.886 1.00 352.94 ? 941 ARG A CZ 1 ATOM 1747 N NH1 . ARG A 1 225 ? 6.182 16.249 -32.742 1.00 353.57 ? 941 ARG A NH1 1 ATOM 1748 N NH2 . ARG A 1 225 ? 6.204 16.242 -35.037 1.00 351.62 ? 941 ARG A NH2 1 ATOM 1749 N N . PRO A 1 226 ? 11.897 10.723 -33.982 1.00 351.35 ? 942 PRO A N 1 ATOM 1750 C CA . PRO A 1 226 ? 13.366 10.731 -34.111 1.00 354.34 ? 942 PRO A CA 1 ATOM 1751 C C . PRO A 1 226 ? 14.161 11.799 -33.364 1.00 358.68 ? 942 PRO A C 1 ATOM 1752 O O . PRO A 1 226 ? 14.998 11.454 -32.523 1.00 366.70 ? 942 PRO A O 1 ATOM 1753 C CB . PRO A 1 226 ? 13.549 10.895 -35.623 1.00 354.13 ? 942 PRO A CB 1 ATOM 1754 C CG . PRO A 1 226 ? 12.413 10.111 -36.190 1.00 354.28 ? 942 PRO A CG 1 ATOM 1755 C CD . PRO A 1 226 ? 11.256 10.220 -35.208 1.00 353.13 ? 942 PRO A CD 1 ATOM 1756 N N . GLY A 1 227 ? 13.930 13.081 -33.640 1.00 349.32 ? 943 GLY A N 1 ATOM 1757 C CA . GLY A 1 227 ? 14.787 14.106 -33.070 1.00 353.45 ? 943 GLY A CA 1 ATOM 1758 C C . GLY A 1 227 ? 14.224 14.859 -31.883 1.00 359.91 ? 943 GLY A C 1 ATOM 1759 O O . GLY A 1 227 ? 14.985 15.450 -31.114 1.00 363.58 ? 943 GLY A O 1 ATOM 1760 N N . LYS A 1 228 ? 12.907 14.840 -31.708 1.00 348.21 ? 944 LYS A N 1 ATOM 1761 C CA . LYS A 1 228 ? 12.255 15.697 -30.726 1.00 351.79 ? 944 LYS A CA 1 ATOM 1762 C C . LYS A 1 228 ? 12.171 15.081 -29.335 1.00 348.99 ? 944 LYS A C 1 ATOM 1763 O O . LYS A 1 228 ? 11.513 15.657 -28.461 1.00 352.84 ? 944 LYS A O 1 ATOM 1764 C CB . LYS A 1 228 ? 10.853 16.070 -31.217 1.00 357.61 ? 944 LYS A CB 1 ATOM 1765 C CG . LYS A 1 228 ? 10.831 16.603 -32.640 1.00 359.65 ? 944 LYS A CG 1 ATOM 1766 C CD . LYS A 1 228 ? 9.879 17.777 -32.780 1.00 363.59 ? 944 LYS A CD 1 ATOM 1767 C CE . LYS A 1 228 ? 9.937 18.365 -34.180 1.00 363.90 ? 944 LYS A CE 1 ATOM 1768 N NZ . LYS A 1 228 ? 11.331 18.700 -34.591 1.00 365.31 ? 944 LYS A NZ 1 ATOM 1769 N N . GLU A 1 229 ? 12.810 13.936 -29.108 1.00 335.90 ? 945 GLU A N 1 ATOM 1770 C CA . GLU A 1 229 ? 12.817 13.325 -27.785 1.00 336.53 ? 945 GLU A CA 1 ATOM 1771 C C . GLU A 1 229 ? 13.460 14.260 -26.766 1.00 331.05 ? 945 GLU A C 1 ATOM 1772 O O . GLU A 1 229 ? 14.299 15.098 -27.104 1.00 331.36 ? 945 GLU A O 1 ATOM 1773 C CB . GLU A 1 229 ? 13.567 11.993 -27.826 1.00 343.81 ? 945 GLU A CB 1 ATOM 1774 C CG . GLU A 1 229 ? 15.032 12.132 -28.211 1.00 352.37 ? 945 GLU A CG 1 ATOM 1775 C CD . GLU A 1 229 ? 15.569 10.909 -28.925 1.00 359.43 ? 945 GLU A CD 1 ATOM 1776 O OE1 . GLU A 1 229 ? 14.761 10.026 -29.283 1.00 366.34 ? 945 GLU A OE1 1 ATOM 1777 O OE2 . GLU A 1 229 ? 16.799 10.831 -29.132 1.00 363.79 ? 945 GLU A OE2 1 ATOM 1778 N N . GLN A 1 230 ? 13.059 14.114 -25.502 1.00 335.81 ? 946 GLN A N 1 ATOM 1779 C CA . GLN A 1 230 ? 13.558 14.995 -24.453 1.00 333.39 ? 946 GLN A CA 1 ATOM 1780 C C . GLN A 1 230 ? 13.458 14.308 -23.097 1.00 332.88 ? 946 GLN A C 1 ATOM 1781 O O . GLN A 1 230 ? 12.508 13.566 -22.839 1.00 334.51 ? 946 GLN A O 1 ATOM 1782 C CB . GLN A 1 230 ? 12.787 16.321 -24.425 1.00 332.69 ? 946 GLN A CB 1 ATOM 1783 C CG . GLN A 1 230 ? 13.288 17.305 -23.376 1.00 337.54 ? 946 GLN A CG 1 ATOM 1784 C CD . GLN A 1 230 ? 12.577 18.638 -23.436 1.00 341.23 ? 946 GLN A CD 1 ATOM 1785 O OE1 . GLN A 1 230 ? 11.518 18.763 -24.050 1.00 337.83 ? 946 GLN A OE1 1 ATOM 1786 N NE2 . GLN A 1 230 ? 13.157 19.647 -22.798 1.00 348.32 ? 946 GLN A NE2 1 ATOM 1787 N N . LEU A 1 231 ? 14.439 14.577 -22.238 1.00 345.43 ? 947 LEU A N 1 ATOM 1788 C CA . LEU A 1 231 ? 14.456 14.049 -20.878 1.00 348.71 ? 947 LEU A CA 1 ATOM 1789 C C . LEU A 1 231 ? 13.638 14.947 -19.957 1.00 348.39 ? 947 LEU A C 1 ATOM 1790 O O . LEU A 1 231 ? 13.938 16.138 -19.817 1.00 348.31 ? 947 LEU A O 1 ATOM 1791 C CB . LEU A 1 231 ? 15.893 13.938 -20.369 1.00 349.53 ? 947 LEU A CB 1 ATOM 1792 C CG . LEU A 1 231 ? 16.611 12.596 -20.496 1.00 350.34 ? 947 LEU A CG 1 ATOM 1793 C CD1 . LEU A 1 231 ? 18.104 12.775 -20.271 1.00 351.02 ? 947 LEU A CD1 1 ATOM 1794 C CD2 . LEU A 1 231 ? 16.041 11.598 -19.502 1.00 351.35 ? 947 LEU A CD2 1 ATOM 1795 N N . SER A 1 232 ? 12.613 14.369 -19.321 1.00 347.22 ? 948 SER A N 1 ATOM 1796 C CA . SER A 1 232 ? 11.773 15.025 -18.322 1.00 347.46 ? 948 SER A CA 1 ATOM 1797 C C . SER A 1 232 ? 11.266 16.376 -18.810 1.00 344.06 ? 948 SER A C 1 ATOM 1798 O O . SER A 1 232 ? 11.756 17.422 -18.367 1.00 341.56 ? 948 SER A O 1 ATOM 1799 C CB . SER A 1 232 ? 12.538 15.193 -17.005 1.00 347.89 ? 948 SER A CB 1 ATOM 1800 O OG . SER A 1 232 ? 13.641 16.071 -17.154 1.00 351.34 ? 948 SER A OG 1 ATOM 1801 N N . PRO A 1 233 ? 10.290 16.400 -19.713 1.00 350.94 ? 949 PRO A N 1 ATOM 1802 C CA . PRO A 1 233 ? 9.770 17.680 -20.202 1.00 347.91 ? 949 PRO A CA 1 ATOM 1803 C C . PRO A 1 233 ? 8.766 18.286 -19.235 1.00 347.15 ? 949 PRO A C 1 ATOM 1804 O O . PRO A 1 233 ? 8.117 17.590 -18.452 1.00 344.29 ? 949 PRO A O 1 ATOM 1805 C CB . PRO A 1 233 ? 9.100 17.309 -21.534 1.00 348.44 ? 949 PRO A CB 1 ATOM 1806 C CG . PRO A 1 233 ? 9.235 15.796 -21.676 1.00 346.38 ? 949 PRO A CG 1 ATOM 1807 C CD . PRO A 1 233 ? 9.606 15.257 -20.335 1.00 348.87 ? 949 PRO A CD 1 ATOM 1808 N N . THR A 1 234 ? 8.648 19.606 -19.300 1.00 353.93 ? 950 THR A N 1 ATOM 1809 C CA . THR A 1 234 ? 7.705 20.311 -18.438 1.00 353.43 ? 950 THR A CA 1 ATOM 1810 C C . THR A 1 234 ? 6.283 20.096 -18.945 1.00 349.21 ? 950 THR A C 1 ATOM 1811 O O . THR A 1 234 ? 6.038 20.211 -20.151 1.00 345.27 ? 950 THR A O 1 ATOM 1812 C CB . THR A 1 234 ? 8.036 21.800 -18.384 1.00 355.19 ? 950 THR A CB 1 ATOM 1813 O OG1 . THR A 1 234 ? 8.248 22.294 -19.710 1.00 354.83 ? 950 THR A OG1 1 ATOM 1814 C CG2 . THR A 1 234 ? 9.288 22.036 -17.552 1.00 357.69 ? 950 THR A CG2 1 ATOM 1815 N N . PRO A 1 235 ? 5.329 19.781 -18.070 1.00 356.42 ? 951 PRO A N 1 ATOM 1816 C CA . PRO A 1 235 ? 3.975 19.465 -18.542 1.00 353.75 ? 951 PRO A CA 1 ATOM 1817 C C . PRO A 1 235 ? 3.239 20.703 -19.033 1.00 351.52 ? 951 PRO A C 1 ATOM 1818 O O . PRO A 1 235 ? 3.382 21.798 -18.482 1.00 348.25 ? 951 PRO A O 1 ATOM 1819 C CB . PRO A 1 235 ? 3.293 18.868 -17.302 1.00 356.14 ? 951 PRO A CB 1 ATOM 1820 C CG . PRO A 1 235 ? 4.410 18.548 -16.345 1.00 358.43 ? 951 PRO A CG 1 ATOM 1821 C CD . PRO A 1 235 ? 5.472 19.561 -16.623 1.00 357.63 ? 951 PRO A CD 1 ATOM 1822 N N . VAL A 1 236 ? 2.435 20.511 -20.076 1.00 354.71 ? 952 VAL A N 1 ATOM 1823 C CA . VAL A 1 236 ? 1.654 21.574 -20.693 1.00 351.78 ? 952 VAL A CA 1 ATOM 1824 C C . VAL A 1 236 ? 0.177 21.313 -20.430 1.00 349.32 ? 952 VAL A C 1 ATOM 1825 O O . VAL A 1 236 ? -0.268 20.162 -20.352 1.00 346.88 ? 952 VAL A O 1 ATOM 1826 C CB . VAL A 1 236 ? 1.949 21.673 -22.207 1.00 350.10 ? 952 VAL A CB 1 ATOM 1827 C CG1 . VAL A 1 236 ? 1.067 22.719 -22.880 1.00 353.10 ? 952 VAL A CG1 1 ATOM 1828 C CG2 . VAL A 1 236 ? 3.416 21.998 -22.433 1.00 349.22 ? 952 VAL A CG2 1 ATOM 1829 N N . LEU A 1 237 ? -0.581 22.398 -20.271 1.00 347.84 ? 953 LEU A N 1 ATOM 1830 C CA . LEU A 1 237 ? -2.023 22.303 -20.084 1.00 344.77 ? 953 LEU A CA 1 ATOM 1831 C C . LEU A 1 237 ? -2.671 21.583 -21.261 1.00 344.55 ? 953 LEU A C 1 ATOM 1832 O O . LEU A 1 237 ? -2.501 21.983 -22.418 1.00 341.54 ? 953 LEU A O 1 ATOM 1833 C CB . LEU A 1 237 ? -2.618 23.702 -19.920 1.00 342.24 ? 953 LEU A CB 1 ATOM 1834 C CG . LEU A 1 237 ? -4.141 23.804 -19.838 1.00 339.35 ? 953 LEU A CG 1 ATOM 1835 C CD1 . LEU A 1 237 ? -4.667 23.054 -18.625 1.00 340.24 ? 953 LEU A CD1 1 ATOM 1836 C CD2 . LEU A 1 237 ? -4.587 25.260 -19.810 1.00 339.19 ? 953 LEU A CD2 1 ATOM 1837 N N . LEU A 1 238 ? -3.412 20.518 -20.962 1.00 337.57 ? 954 LEU A N 1 ATOM 1838 C CA . LEU A 1 238 ? -4.119 19.741 -21.974 1.00 338.22 ? 954 LEU A CA 1 ATOM 1839 C C . LEU A 1 238 ? -5.621 19.981 -21.918 1.00 340.62 ? 954 LEU A C 1 ATOM 1840 O O . LEU A 1 238 ? -6.201 20.510 -22.870 1.00 346.11 ? 954 LEU A O 1 ATOM 1841 C CB . LEU A 1 238 ? -3.814 18.246 -21.805 1.00 338.06 ? 954 LEU A CB 1 ATOM 1842 C CG . LEU A 1 238 ? -2.344 17.825 -21.754 1.00 339.30 ? 954 LEU A CG 1 ATOM 1843 C CD1 . LEU A 1 238 ? -2.232 16.335 -21.480 1.00 339.92 ? 954 LEU A CD1 1 ATOM 1844 C CD2 . LEU A 1 238 ? -1.626 18.187 -23.043 1.00 338.88 ? 954 LEU A CD2 1 ATOM 1845 N N . GLU A 1 239 ? -6.269 19.601 -20.819 1.00 339.72 ? 955 GLU A N 1 ATOM 1846 C CA . GLU A 1 239 ? -7.701 19.781 -20.644 1.00 341.57 ? 955 GLU A CA 1 ATOM 1847 C C . GLU A 1 239 ? -7.976 20.707 -19.469 1.00 341.72 ? 955 GLU A C 1 ATOM 1848 O O . GLU A 1 239 ? -7.218 20.744 -18.495 1.00 344.57 ? 955 GLU A O 1 ATOM 1849 C CB . GLU A 1 239 ? -8.412 18.444 -20.394 1.00 345.23 ? 955 GLU A CB 1 ATOM 1850 C CG . GLU A 1 239 ? -8.090 17.343 -21.383 1.00 350.24 ? 955 GLU A CG 1 ATOM 1851 C CD . GLU A 1 239 ? -8.866 16.073 -21.091 1.00 355.66 ? 955 GLU A CD 1 ATOM 1852 O OE1 . GLU A 1 239 ? -9.715 15.686 -21.923 1.00 363.69 ? 955 GLU A OE1 1 ATOM 1853 O OE2 . GLU A 1 239 ? -8.639 15.470 -20.021 1.00 351.14 ? 955 GLU A OE2 1 ATOM 1854 N N . ILE A 1 240 ? -9.071 21.452 -19.572 1.00 327.17 ? 956 ILE A N 1 ATOM 1855 C CA . ILE A 1 240 ? -9.635 22.191 -18.450 1.00 325.31 ? 956 ILE A CA 1 ATOM 1856 C C . ILE A 1 240 ? -10.876 21.429 -18.007 1.00 331.95 ? 956 ILE A C 1 ATOM 1857 O O . ILE A 1 240 ? -11.907 21.451 -18.688 1.00 336.86 ? 956 ILE A O 1 ATOM 1858 C CB . ILE A 1 240 ? -9.963 23.641 -18.826 1.00 321.91 ? 956 ILE A CB 1 ATOM 1859 C CG1 . ILE A 1 240 ? -8.682 24.408 -19.162 1.00 322.94 ? 956 ILE A CG1 1 ATOM 1860 C CG2 . ILE A 1 240 ? -10.714 24.324 -17.698 1.00 321.97 ? 956 ILE A CG2 1 ATOM 1861 C CD1 . ILE A 1 240 ? -8.918 25.855 -19.539 1.00 324.02 ? 956 ILE A CD1 1 ATOM 1862 N N . ASN A 1 241 ? -10.776 20.738 -16.871 1.00 342.28 ? 957 ASN A N 1 ATOM 1863 C CA . ASN A 1 241 ? -11.841 19.829 -16.461 1.00 345.90 ? 957 ASN A CA 1 ATOM 1864 C C . ASN A 1 241 ? -12.993 20.564 -15.786 1.00 348.38 ? 957 ASN A C 1 ATOM 1865 O O . ASN A 1 241 ? -14.161 20.223 -16.007 1.00 353.35 ? 957 ASN A O 1 ATOM 1866 C CB . ASN A 1 241 ? -11.278 18.750 -15.534 1.00 348.10 ? 957 ASN A CB 1 ATOM 1867 C CG . ASN A 1 241 ? -10.125 17.987 -16.160 1.00 348.87 ? 957 ASN A CG 1 ATOM 1868 O OD1 . ASN A 1 241 ? -9.068 17.826 -15.549 1.00 352.58 ? 957 ASN A OD1 1 ATOM 1869 N ND2 . ASN A 1 241 ? -10.321 17.517 -17.387 1.00 350.13 ? 957 ASN A ND2 1 ATOM 1870 N N . ARG A 1 242 ? -12.694 21.566 -14.961 1.00 347.49 ? 958 ARG A N 1 ATOM 1871 C CA . ARG A 1 242 ? -13.723 22.289 -14.228 1.00 347.64 ? 958 ARG A CA 1 ATOM 1872 C C . ARG A 1 242 ? -13.399 23.774 -14.191 1.00 345.14 ? 958 ARG A C 1 ATOM 1873 O O . ARG A 1 242 ? -12.242 24.161 -14.002 1.00 344.07 ? 958 ARG A O 1 ATOM 1874 C CB . ARG A 1 242 ? -13.869 21.759 -12.792 1.00 349.29 ? 958 ARG A CB 1 ATOM 1875 C CG . ARG A 1 242 ? -14.629 20.448 -12.683 1.00 353.12 ? 958 ARG A CG 1 ATOM 1876 C CD . ARG A 1 242 ? -14.886 20.071 -11.231 1.00 356.34 ? 958 ARG A CD 1 ATOM 1877 N NE . ARG A 1 242 ? -15.498 21.165 -10.479 1.00 357.03 ? 958 ARG A NE 1 ATOM 1878 C CZ . ARG A 1 242 ? -14.907 21.800 -9.472 1.00 355.81 ? 958 ARG A CZ 1 ATOM 1879 N NH1 . ARG A 1 242 ? -13.690 21.442 -9.085 1.00 356.95 ? 958 ARG A NH1 1 ATOM 1880 N NH2 . ARG A 1 242 ? -15.535 22.785 -8.843 1.00 353.28 ? 958 ARG A NH2 1 ATOM 1881 N N . VAL A 1 243 ? -14.429 24.597 -14.369 1.00 334.53 ? 959 VAL A N 1 ATOM 1882 C CA . VAL A 1 243 ? -14.326 26.043 -14.231 1.00 336.80 ? 959 VAL A CA 1 ATOM 1883 C C . VAL A 1 243 ? -15.373 26.509 -13.230 1.00 339.84 ? 959 VAL A C 1 ATOM 1884 O O . VAL A 1 243 ? -16.416 25.871 -13.050 1.00 346.98 ? 959 VAL A O 1 ATOM 1885 C CB . VAL A 1 243 ? -14.499 26.777 -15.580 1.00 335.22 ? 959 VAL A CB 1 ATOM 1886 C CG1 . VAL A 1 243 ? -13.299 26.533 -16.476 1.00 335.39 ? 959 VAL A CG1 1 ATOM 1887 C CG2 . VAL A 1 243 ? -15.782 26.333 -16.265 1.00 336.12 ? 959 VAL A CG2 1 ATOM 1888 N N . VAL A 1 244 ? -15.082 27.626 -12.569 1.00 331.79 ? 960 VAL A N 1 ATOM 1889 C CA . VAL A 1 244 ? -15.984 28.210 -11.577 1.00 330.82 ? 960 VAL A CA 1 ATOM 1890 C C . VAL A 1 244 ? -16.093 29.706 -11.846 1.00 331.00 ? 960 VAL A C 1 ATOM 1891 O O . VAL A 1 244 ? -15.064 30.381 -11.996 1.00 326.55 ? 960 VAL A O 1 ATOM 1892 C CB . VAL A 1 244 ? -15.497 27.930 -10.145 1.00 331.40 ? 960 VAL A CB 1 ATOM 1893 C CG1 . VAL A 1 244 ? -16.385 28.636 -9.131 1.00 333.92 ? 960 VAL A CG1 1 ATOM 1894 C CG2 . VAL A 1 244 ? -15.465 26.432 -9.869 1.00 331.60 ? 960 VAL A CG2 1 ATOM 1895 N N . PRO A 1 245 ? -17.301 30.264 -11.915 1.00 323.03 ? 961 PRO A N 1 ATOM 1896 C CA . PRO A 1 245 ? -17.440 31.681 -12.273 1.00 323.02 ? 961 PRO A CA 1 ATOM 1897 C C . PRO A 1 245 ? -16.815 32.600 -11.236 1.00 326.13 ? 961 PRO A C 1 ATOM 1898 O O . PRO A 1 245 ? -16.774 32.297 -10.041 1.00 322.99 ? 961 PRO A O 1 ATOM 1899 C CB . PRO A 1 245 ? -18.959 31.885 -12.345 1.00 322.74 ? 961 PRO A CB 1 ATOM 1900 C CG . PRO A 1 245 ? -19.533 30.517 -12.495 1.00 321.70 ? 961 PRO A CG 1 ATOM 1901 C CD . PRO A 1 245 ? -18.607 29.604 -11.758 1.00 321.15 ? 961 PRO A CD 1 ATOM 1902 N N . LEU A 1 246 ? -16.330 33.748 -11.715 1.00 326.50 ? 962 LEU A N 1 ATOM 1903 C CA . LEU A 1 246 ? -15.654 34.699 -10.842 1.00 325.50 ? 962 LEU A CA 1 ATOM 1904 C C . LEU A 1 246 ? -16.605 35.431 -9.905 1.00 329.93 ? 962 LEU A C 1 ATOM 1905 O O . LEU A 1 246 ? -16.133 36.082 -8.967 1.00 332.09 ? 962 LEU A O 1 ATOM 1906 C CB . LEU A 1 246 ? -14.867 35.717 -11.671 1.00 322.81 ? 962 LEU A CB 1 ATOM 1907 C CG . LEU A 1 246 ? -13.603 35.221 -12.378 1.00 320.55 ? 962 LEU A CG 1 ATOM 1908 C CD1 . LEU A 1 246 ? -12.832 36.386 -12.986 1.00 320.42 ? 962 LEU A CD1 1 ATOM 1909 C CD2 . LEU A 1 246 ? -12.720 34.430 -11.424 1.00 318.74 ? 962 LEU A CD2 1 ATOM 1910 N N . TYR A 1 247 ? -17.920 35.351 -10.124 1.00 322.69 ? 963 TYR A N 1 ATOM 1911 C CA . TYR A 1 247 ? -18.828 35.960 -9.160 1.00 327.50 ? 963 TYR A CA 1 ATOM 1912 C C . TYR A 1 247 ? -18.963 35.139 -7.885 1.00 328.64 ? 963 TYR A C 1 ATOM 1913 O O . TYR A 1 247 ? -19.631 35.585 -6.949 1.00 332.45 ? 963 TYR A O 1 ATOM 1914 C CB . TYR A 1 247 ? -20.208 36.225 -9.785 1.00 328.98 ? 963 TYR A CB 1 ATOM 1915 C CG . TYR A 1 247 ? -20.955 35.036 -10.363 1.00 330.68 ? 963 TYR A CG 1 ATOM 1916 C CD1 . TYR A 1 247 ? -21.533 34.078 -9.536 1.00 330.38 ? 963 TYR A CD1 1 ATOM 1917 C CD2 . TYR A 1 247 ? -21.137 34.909 -11.736 1.00 332.66 ? 963 TYR A CD2 1 ATOM 1918 C CE1 . TYR A 1 247 ? -22.234 33.007 -10.063 1.00 330.32 ? 963 TYR A CE1 1 ATOM 1919 C CE2 . TYR A 1 247 ? -21.839 33.845 -12.271 1.00 332.59 ? 963 TYR A CE2 1 ATOM 1920 C CZ . TYR A 1 247 ? -22.385 32.895 -11.430 1.00 331.27 ? 963 TYR A CZ 1 ATOM 1921 O OH . TYR A 1 247 ? -23.084 31.832 -11.955 1.00 329.20 ? 963 TYR A OH 1 ATOM 1922 N N . THR A 1 248 ? -18.341 33.960 -7.830 1.00 331.99 ? 964 THR A N 1 ATOM 1923 C CA . THR A 1 248 ? -18.232 33.235 -6.570 1.00 332.82 ? 964 THR A CA 1 ATOM 1924 C C . THR A 1 248 ? -17.341 33.982 -5.586 1.00 332.20 ? 964 THR A C 1 ATOM 1925 O O . THR A 1 248 ? -17.545 33.902 -4.368 1.00 332.45 ? 964 THR A O 1 ATOM 1926 C CB . THR A 1 248 ? -17.681 31.828 -6.826 1.00 333.16 ? 964 THR A CB 1 ATOM 1927 O OG1 . THR A 1 248 ? -18.508 31.158 -7.782 1.00 332.62 ? 964 THR A OG1 1 ATOM 1928 C CG2 . THR A 1 248 ? -17.633 31.012 -5.542 1.00 332.35 ? 964 THR A CG2 1 ATOM 1929 N N . LEU A 1 249 ? -16.368 34.734 -6.094 1.00 334.99 ? 965 LEU A N 1 ATOM 1930 C CA . LEU A 1 249 ? -15.353 35.383 -5.275 1.00 338.39 ? 965 LEU A CA 1 ATOM 1931 C C . LEU A 1 249 ? -15.756 36.770 -4.794 1.00 343.91 ? 965 LEU A C 1 ATOM 1932 O O . LEU A 1 249 ? -14.942 37.444 -4.154 1.00 346.11 ? 965 LEU A O 1 ATOM 1933 C CB . LEU A 1 249 ? -14.040 35.481 -6.058 1.00 336.49 ? 965 LEU A CB 1 ATOM 1934 C CG . LEU A 1 249 ? -13.068 34.298 -6.090 1.00 335.97 ? 965 LEU A CG 1 ATOM 1935 C CD1 . LEU A 1 249 ? -13.762 32.983 -6.393 1.00 335.65 ? 965 LEU A CD1 1 ATOM 1936 C CD2 . LEU A 1 249 ? -11.996 34.565 -7.122 1.00 336.23 ? 965 LEU A CD2 1 ATOM 1937 N N . ILE A 1 250 ? -16.984 37.209 -5.070 1.00 323.54 ? 966 ILE A N 1 ATOM 1938 C CA . ILE A 1 250 ? -17.350 38.589 -4.770 1.00 327.84 ? 966 ILE A CA 1 ATOM 1939 C C . ILE A 1 250 ? -17.618 38.774 -3.283 1.00 334.25 ? 966 ILE A C 1 ATOM 1940 O O . ILE A 1 250 ? -17.291 39.822 -2.708 1.00 335.34 ? 966 ILE A O 1 ATOM 1941 C CB . ILE A 1 250 ? -18.555 39.009 -5.628 1.00 325.06 ? 966 ILE A CB 1 ATOM 1942 C CG1 . ILE A 1 250 ? -18.199 38.818 -7.105 1.00 323.94 ? 966 ILE A CG1 1 ATOM 1943 C CG2 . ILE A 1 250 ? -18.953 40.446 -5.325 1.00 325.26 ? 966 ILE A CG2 1 ATOM 1944 C CD1 . ILE A 1 250 ? -18.896 39.775 -8.039 1.00 327.36 ? 966 ILE A CD1 1 ATOM 1945 N N . GLN A 1 251 ? -18.204 37.762 -2.639 1.00 321.58 ? 967 GLN A N 1 ATOM 1946 C CA . GLN A 1 251 ? -18.490 37.685 -1.200 1.00 321.52 ? 967 GLN A CA 1 ATOM 1947 C C . GLN A 1 251 ? -19.666 38.552 -0.766 1.00 313.06 ? 967 GLN A C 1 ATOM 1948 O O . GLN A 1 251 ? -19.850 38.749 0.443 1.00 304.47 ? 967 GLN A O 1 ATOM 1949 C CB . GLN A 1 251 ? -17.278 38.052 -0.335 1.00 322.98 ? 967 GLN A CB 1 ATOM 1950 C CG . GLN A 1 251 ? -16.049 37.192 -0.576 1.00 326.90 ? 967 GLN A CG 1 ATOM 1951 C CD . GLN A 1 251 ? -14.840 37.671 0.207 1.00 329.40 ? 967 GLN A CD 1 ATOM 1952 O OE1 . GLN A 1 251 ? -14.744 38.843 0.572 1.00 332.73 ? 967 GLN A OE1 1 ATOM 1953 N NE2 . GLN A 1 251 ? -13.909 36.761 0.472 1.00 330.22 ? 967 GLN A NE2 1 ATOM 1954 N N . ASP A 1 252 ? -20.469 39.075 -1.691 1.00 321.27 ? 968 ASP A N 1 ATOM 1955 C CA . ASP A 1 252 ? -21.631 39.868 -1.320 1.00 320.44 ? 968 ASP A CA 1 ATOM 1956 C C . ASP A 1 252 ? -22.740 39.624 -2.332 1.00 320.53 ? 968 ASP A C 1 ATOM 1957 O O . ASP A 1 252 ? -22.479 39.334 -3.498 1.00 325.94 ? 968 ASP A O 1 ATOM 1958 C CB . ASP A 1 252 ? -21.298 41.364 -1.238 1.00 319.07 ? 968 ASP A CB 1 ATOM 1959 C CG . ASP A 1 252 ? -20.979 41.971 -2.592 1.00 316.52 ? 968 ASP A CG 1 ATOM 1960 O OD1 . ASP A 1 252 ? -21.921 42.186 -3.384 1.00 312.10 ? 968 ASP A OD1 1 ATOM 1961 O OD2 . ASP A 1 252 ? -19.791 42.243 -2.861 1.00 312.90 ? 968 ASP A OD2 1 ATOM 1962 N N . ASN A 1 253 ? -23.986 39.765 -1.877 1.00 312.52 ? 969 ASN A N 1 ATOM 1963 C CA . ASN A 1 253 ? -25.121 39.476 -2.749 1.00 312.25 ? 969 ASN A CA 1 ATOM 1964 C C . ASN A 1 253 ? -25.457 40.628 -3.688 1.00 314.35 ? 969 ASN A C 1 ATOM 1965 O O . ASN A 1 253 ? -26.011 40.391 -4.766 1.00 316.70 ? 969 ASN A O 1 ATOM 1966 C CB . ASN A 1 253 ? -26.351 39.114 -1.913 1.00 309.58 ? 969 ASN A CB 1 ATOM 1967 C CG . ASN A 1 253 ? -26.128 37.892 -1.045 1.00 307.70 ? 969 ASN A CG 1 ATOM 1968 O OD1 . ASN A 1 253 ? -25.165 37.151 -1.232 1.00 304.76 ? 969 ASN A OD1 1 ATOM 1969 N ND2 . ASN A 1 253 ? -27.025 37.674 -0.088 1.00 307.54 ? 969 ASN A ND2 1 ATOM 1970 N N . GLY A 1 254 ? -25.143 41.867 -3.307 1.00 319.35 ? 970 GLY A N 1 ATOM 1971 C CA . GLY A 1 254 ? -25.521 43.003 -4.132 1.00 317.59 ? 970 GLY A CA 1 ATOM 1972 C C . GLY A 1 254 ? -24.710 43.115 -5.408 1.00 316.89 ? 970 GLY A C 1 ATOM 1973 O O . GLY A 1 254 ? -25.261 43.365 -6.485 1.00 316.49 ? 970 GLY A O 1 ATOM 1974 N N . THR A 1 255 ? -23.395 42.932 -5.309 1.00 320.11 ? 971 THR A N 1 ATOM 1975 C CA . THR A 1 255 ? -22.540 43.090 -6.480 1.00 324.04 ? 971 THR A CA 1 ATOM 1976 C C . THR A 1 255 ? -22.509 41.827 -7.332 1.00 326.46 ? 971 THR A C 1 ATOM 1977 O O . THR A 1 255 ? -22.513 41.913 -8.566 1.00 324.37 ? 971 THR A O 1 ATOM 1978 C CB . THR A 1 255 ? -21.121 43.485 -6.055 1.00 323.36 ? 971 THR A CB 1 ATOM 1979 O OG1 . THR A 1 255 ? -21.166 44.706 -5.306 1.00 322.01 ? 971 THR A OG1 1 ATOM 1980 C CG2 . THR A 1 255 ? -20.223 43.675 -7.268 1.00 323.61 ? 971 THR A CG2 1 ATOM 1981 N N . LYS A 1 256 ? -22.493 40.646 -6.706 1.00 321.34 ? 972 LYS A N 1 ATOM 1982 C CA . LYS A 1 256 ? -22.362 39.418 -7.484 1.00 317.96 ? 972 LYS A CA 1 ATOM 1983 C C . LYS A 1 256 ? -23.614 39.093 -8.290 1.00 321.47 ? 972 LYS A C 1 ATOM 1984 O O . LYS A 1 256 ? -23.553 38.231 -9.174 1.00 327.42 ? 972 LYS A O 1 ATOM 1985 C CB . LYS A 1 256 ? -21.996 38.236 -6.578 1.00 315.05 ? 972 LYS A CB 1 ATOM 1986 C CG . LYS A 1 256 ? -23.152 37.519 -5.902 1.00 311.96 ? 972 LYS A CG 1 ATOM 1987 C CD . LYS A 1 256 ? -22.649 36.262 -5.195 1.00 311.38 ? 972 LYS A CD 1 ATOM 1988 C CE . LYS A 1 256 ? -21.448 36.557 -4.295 1.00 312.32 ? 972 LYS A CE 1 ATOM 1989 N NZ . LYS A 1 256 ? -21.037 35.372 -3.488 1.00 313.20 ? 972 LYS A NZ 1 ATOM 1990 N N . GLU A 1 257 ? -24.738 39.753 -8.016 1.00 327.72 ? 973 GLU A N 1 ATOM 1991 C CA . GLU A 1 257 ? -25.877 39.635 -8.918 1.00 328.13 ? 973 GLU A CA 1 ATOM 1992 C C . GLU A 1 257 ? -25.756 40.617 -10.075 1.00 326.88 ? 973 GLU A C 1 ATOM 1993 O O . GLU A 1 257 ? -26.142 40.301 -11.206 1.00 327.07 ? 973 GLU A O 1 ATOM 1994 C CB . GLU A 1 257 ? -27.183 39.856 -8.155 1.00 331.56 ? 973 GLU A CB 1 ATOM 1995 C CG . GLU A 1 257 ? -28.414 39.399 -8.915 1.00 335.56 ? 973 GLU A CG 1 ATOM 1996 C CD . GLU A 1 257 ? -28.513 37.891 -8.995 1.00 338.01 ? 973 GLU A CD 1 ATOM 1997 O OE1 . GLU A 1 257 ? -28.345 37.227 -7.950 1.00 339.17 ? 973 GLU A OE1 1 ATOM 1998 O OE2 . GLU A 1 257 ? -28.752 37.369 -10.103 1.00 341.06 ? 973 GLU A OE2 1 ATOM 1999 N N . ALA A 1 258 ? -25.210 41.809 -9.810 1.00 328.53 ? 974 ALA A N 1 ATOM 2000 C CA . ALA A 1 258 ? -24.995 42.797 -10.862 1.00 328.52 ? 974 ALA A CA 1 ATOM 2001 C C . ALA A 1 258 ? -23.827 42.429 -11.768 1.00 327.93 ? 974 ALA A C 1 ATOM 2002 O O . ALA A 1 258 ? -23.842 42.762 -12.956 1.00 326.33 ? 974 ALA A O 1 ATOM 2003 C CB . ALA A 1 258 ? -24.767 44.177 -10.244 1.00 329.29 ? 974 ALA A CB 1 ATOM 2004 N N . PHE A 1 259 ? -22.806 41.765 -11.225 1.00 321.53 ? 975 PHE A N 1 ATOM 2005 C CA . PHE A 1 259 ? -21.716 41.265 -12.058 1.00 323.97 ? 975 PHE A CA 1 ATOM 2006 C C . PHE A 1 259 ? -22.200 40.151 -12.975 1.00 316.58 ? 975 PHE A C 1 ATOM 2007 O O . PHE A 1 259 ? -21.809 40.084 -14.145 1.00 314.46 ? 975 PHE A O 1 ATOM 2008 C CB . PHE A 1 259 ? -20.568 40.771 -11.171 1.00 331.43 ? 975 PHE A CB 1 ATOM 2009 C CG . PHE A 1 259 ? -19.409 40.185 -11.933 1.00 341.84 ? 975 PHE A CG 1 ATOM 2010 C CD1 . PHE A 1 259 ? -19.394 38.842 -12.286 1.00 347.83 ? 975 PHE A CD1 1 ATOM 2011 C CD2 . PHE A 1 259 ? -18.323 40.972 -12.275 1.00 348.62 ? 975 PHE A CD2 1 ATOM 2012 C CE1 . PHE A 1 259 ? -18.328 38.305 -12.980 1.00 351.98 ? 975 PHE A CE1 1 ATOM 2013 C CE2 . PHE A 1 259 ? -17.253 40.438 -12.966 1.00 353.76 ? 975 PHE A CE2 1 ATOM 2014 C CZ . PHE A 1 259 ? -17.256 39.103 -13.318 1.00 353.85 ? 975 PHE A CZ 1 ATOM 2015 N N . LYS A 1 260 ? -23.049 39.265 -12.452 1.00 325.36 ? 976 LYS A N 1 ATOM 2016 C CA . LYS A 1 260 ? -23.527 38.120 -13.219 1.00 319.55 ? 976 LYS A CA 1 ATOM 2017 C C . LYS A 1 260 ? -24.285 38.562 -14.464 1.00 317.37 ? 976 LYS A C 1 ATOM 2018 O O . LYS A 1 260 ? -24.135 37.964 -15.536 1.00 318.93 ? 976 LYS A O 1 ATOM 2019 C CB . LYS A 1 260 ? -24.407 37.243 -12.325 1.00 316.59 ? 976 LYS A CB 1 ATOM 2020 C CG . LYS A 1 260 ? -24.992 36.008 -12.985 1.00 316.24 ? 976 LYS A CG 1 ATOM 2021 C CD . LYS A 1 260 ? -25.978 35.329 -12.041 1.00 318.64 ? 976 LYS A CD 1 ATOM 2022 C CE . LYS A 1 260 ? -26.622 34.103 -12.671 1.00 318.82 ? 976 LYS A CE 1 ATOM 2023 N NZ . LYS A 1 260 ? -25.667 32.968 -12.805 1.00 321.75 ? 976 LYS A NZ 1 ATOM 2024 N N . SER A 1 261 ? -25.100 39.611 -14.343 1.00 327.05 ? 977 SER A N 1 ATOM 2025 C CA . SER A 1 261 ? -25.850 40.099 -15.495 1.00 326.10 ? 977 SER A CA 1 ATOM 2026 C C . SER A 1 261 ? -24.937 40.740 -16.531 1.00 323.68 ? 977 SER A C 1 ATOM 2027 O O . SER A 1 261 ? -25.223 40.675 -17.732 1.00 327.67 ? 977 SER A O 1 ATOM 2028 C CB . SER A 1 261 ? -26.924 41.089 -15.043 1.00 323.96 ? 977 SER A CB 1 ATOM 2029 O OG . SER A 1 261 ? -26.345 42.187 -14.361 1.00 324.77 ? 977 SER A OG 1 ATOM 2030 N N . ALA A 1 262 ? -23.840 41.359 -16.091 1.00 328.80 ? 978 ALA A N 1 ATOM 2031 C CA . ALA A 1 262 ? -22.875 41.910 -17.035 1.00 327.86 ? 978 ALA A CA 1 ATOM 2032 C C . ALA A 1 262 ? -22.092 40.810 -17.739 1.00 327.08 ? 978 ALA A C 1 ATOM 2033 O O . ALA A 1 262 ? -21.687 40.981 -18.894 1.00 327.54 ? 978 ALA A O 1 ATOM 2034 C CB . ALA A 1 262 ? -21.923 42.868 -16.319 1.00 329.62 ? 978 ALA A CB 1 ATOM 2035 N N . LEU A 1 263 ? -21.868 39.682 -17.062 1.00 332.81 ? 979 LEU A N 1 ATOM 2036 C CA . LEU A 1 263 ? -21.202 38.550 -17.699 1.00 330.72 ? 979 LEU A CA 1 ATOM 2037 C C . LEU A 1 263 ? -22.069 37.961 -18.802 1.00 327.09 ? 979 LEU A C 1 ATOM 2038 O O . LEU A 1 263 ? -21.584 37.680 -19.905 1.00 326.92 ? 979 LEU A O 1 ATOM 2039 C CB . LEU A 1 263 ? -20.856 37.490 -16.648 1.00 330.80 ? 979 LEU A CB 1 ATOM 2040 C CG . LEU A 1 263 ? -19.962 36.301 -17.021 1.00 330.35 ? 979 LEU A CG 1 ATOM 2041 C CD1 . LEU A 1 263 ? -20.741 35.161 -17.675 1.00 330.97 ? 979 LEU A CD1 1 ATOM 2042 C CD2 . LEU A 1 263 ? -18.822 36.760 -17.916 1.00 328.67 ? 979 LEU A CD2 1 ATOM 2043 N N . MET A 1 264 ? -23.359 37.764 -18.519 1.00 325.64 ? 980 MET A N 1 ATOM 2044 C CA . MET A 1 264 ? -24.265 37.230 -19.529 1.00 323.66 ? 980 MET A CA 1 ATOM 2045 C C . MET A 1 264 ? -24.394 38.170 -20.719 1.00 321.49 ? 980 MET A C 1 ATOM 2046 O O . MET A 1 264 ? -24.640 37.720 -21.844 1.00 324.30 ? 980 MET A O 1 ATOM 2047 C CB . MET A 1 264 ? -25.641 36.963 -18.917 1.00 322.93 ? 980 MET A CB 1 ATOM 2048 C CG . MET A 1 264 ? -25.641 36.053 -17.702 1.00 324.64 ? 980 MET A CG 1 ATOM 2049 S SD . MET A 1 264 ? -27.278 35.843 -16.965 1.00 328.82 ? 980 MET A SD 1 ATOM 2050 C CE . MET A 1 264 ? -28.066 34.735 -18.134 1.00 325.58 ? 980 MET A CE 1 ATOM 2051 N N . SER A 1 265 ? -24.235 39.476 -20.494 1.00 321.08 ? 981 SER A N 1 ATOM 2052 C CA . SER A 1 265 ? -24.284 40.429 -21.597 1.00 322.68 ? 981 SER A CA 1 ATOM 2053 C C . SER A 1 265 ? -23.089 40.263 -22.525 1.00 323.73 ? 981 SER A C 1 ATOM 2054 O O . SER A 1 265 ? -23.237 40.306 -23.752 1.00 325.58 ? 981 SER A O 1 ATOM 2055 C CB . SER A 1 265 ? -24.345 41.857 -21.053 1.00 324.32 ? 981 SER A CB 1 ATOM 2056 O OG . SER A 1 265 ? -24.272 42.806 -22.102 1.00 327.00 ? 981 SER A OG 1 ATOM 2057 N N . SER A 1 266 ? -21.898 40.068 -21.958 1.00 330.03 ? 982 SER A N 1 ATOM 2058 C CA . SER A 1 266 ? -20.703 39.925 -22.781 1.00 331.04 ? 982 SER A CA 1 ATOM 2059 C C . SER A 1 266 ? -20.684 38.597 -23.524 1.00 326.78 ? 982 SER A C 1 ATOM 2060 O O . SER A 1 266 ? -20.139 38.516 -24.632 1.00 323.92 ? 982 SER A O 1 ATOM 2061 C CB . SER A 1 266 ? -19.449 40.064 -21.916 1.00 333.82 ? 982 SER A CB 1 ATOM 2062 O OG . SER A 1 266 ? -19.348 38.990 -20.997 1.00 335.54 ? 982 SER A OG 1 ATOM 2063 N N . TYR A 1 267 ? -21.275 37.553 -22.943 1.00 324.03 ? 983 TYR A N 1 ATOM 2064 C CA . TYR A 1 267 ? -21.226 36.231 -23.556 1.00 323.50 ? 983 TYR A CA 1 ATOM 2065 C C . TYR A 1 267 ? -22.330 36.052 -24.593 1.00 321.77 ? 983 TYR A C 1 ATOM 2066 O O . TYR A 1 267 ? -22.057 35.695 -25.745 1.00 320.19 ? 983 TYR A O 1 ATOM 2067 C CB . TYR A 1 267 ? -21.323 35.150 -22.476 1.00 324.80 ? 983 TYR A CB 1 ATOM 2068 C CG . TYR A 1 267 ? -21.024 33.751 -22.971 1.00 329.87 ? 983 TYR A CG 1 ATOM 2069 C CD1 . TYR A 1 267 ? -19.720 33.273 -23.011 1.00 330.70 ? 983 TYR A CD1 1 ATOM 2070 C CD2 . TYR A 1 267 ? -22.044 32.908 -23.393 1.00 330.44 ? 983 TYR A CD2 1 ATOM 2071 C CE1 . TYR A 1 267 ? -19.440 31.996 -23.460 1.00 328.56 ? 983 TYR A CE1 1 ATOM 2072 C CE2 . TYR A 1 267 ? -21.773 31.628 -23.845 1.00 330.72 ? 983 TYR A CE2 1 ATOM 2073 C CZ . TYR A 1 267 ? -20.469 31.178 -23.876 1.00 330.09 ? 983 TYR A CZ 1 ATOM 2074 O OH . TYR A 1 267 ? -20.191 29.907 -24.323 1.00 334.83 ? 983 TYR A OH 1 ATOM 2075 N N . TRP A 1 268 ? -23.580 36.305 -24.207 1.00 332.84 ? 984 TRP A N 1 ATOM 2076 C CA . TRP A 1 268 ? -24.716 35.989 -25.065 1.00 329.36 ? 984 TRP A CA 1 ATOM 2077 C C . TRP A 1 268 ? -25.118 37.138 -25.983 1.00 330.34 ? 984 TRP A C 1 ATOM 2078 O O . TRP A 1 268 ? -25.504 36.898 -27.131 1.00 330.54 ? 984 TRP A O 1 ATOM 2079 C CB . TRP A 1 268 ? -25.918 35.571 -24.213 1.00 329.57 ? 984 TRP A CB 1 ATOM 2080 C CG . TRP A 1 268 ? -25.680 34.341 -23.388 1.00 330.63 ? 984 TRP A CG 1 ATOM 2081 C CD1 . TRP A 1 268 ? -25.502 34.283 -22.037 1.00 331.58 ? 984 TRP A CD1 1 ATOM 2082 C CD2 . TRP A 1 268 ? -25.591 32.991 -23.862 1.00 330.40 ? 984 TRP A CD2 1 ATOM 2083 N NE1 . TRP A 1 268 ? -25.312 32.981 -21.639 1.00 332.92 ? 984 TRP A NE1 1 ATOM 2084 C CE2 . TRP A 1 268 ? -25.361 32.169 -22.741 1.00 331.32 ? 984 TRP A CE2 1 ATOM 2085 C CE3 . TRP A 1 268 ? -25.685 32.399 -25.125 1.00 330.49 ? 984 TRP A CE3 1 ATOM 2086 C CZ2 . TRP A 1 268 ? -25.223 30.786 -22.845 1.00 331.39 ? 984 TRP A CZ2 1 ATOM 2087 C CZ3 . TRP A 1 268 ? -25.548 31.027 -25.226 1.00 331.95 ? 984 TRP A CZ3 1 ATOM 2088 C CH2 . TRP A 1 268 ? -25.319 30.235 -24.093 1.00 331.96 ? 984 TRP A CH2 1 ATOM 2089 N N . CYS A 1 269 ? -25.044 38.381 -25.509 1.00 321.23 ? 985 CYS A N 1 ATOM 2090 C CA . CYS A 1 269 ? -25.555 39.525 -26.255 1.00 326.23 ? 985 CYS A CA 1 ATOM 2091 C C . CYS A 1 269 ? -24.439 40.443 -26.758 1.00 326.30 ? 985 CYS A C 1 ATOM 2092 O O . CYS A 1 269 ? -24.655 41.645 -26.939 1.00 327.82 ? 985 CYS A O 1 ATOM 2093 C CB . CYS A 1 269 ? -26.553 40.313 -25.405 1.00 329.52 ? 985 CYS A CB 1 ATOM 2094 S SG . CYS A 1 269 ? -27.705 39.311 -24.409 1.00 337.17 ? 985 CYS A SG 1 ATOM 2095 N N . SER A 1 270 ? -23.245 39.888 -26.987 1.00 324.84 ? 986 SER A N 1 ATOM 2096 C CA . SER A 1 270 ? -22.101 40.610 -27.560 1.00 327.29 ? 986 SER A CA 1 ATOM 2097 C C . SER A 1 270 ? -21.755 41.876 -26.780 1.00 326.11 ? 986 SER A C 1 ATOM 2098 O O . SER A 1 270 ? -21.155 42.806 -27.327 1.00 322.02 ? 986 SER A O 1 ATOM 2099 C CB . SER A 1 270 ? -22.339 40.949 -29.035 1.00 327.44 ? 986 SER A CB 1 ATOM 2100 O OG . SER A 1 270 ? -21.223 41.611 -29.606 1.00 333.02 ? 986 SER A OG 1 ATOM 2101 N N . GLY A 1 271 ? -22.127 41.928 -25.504 1.00 325.41 ? 987 GLY A N 1 ATOM 2102 C CA . GLY A 1 271 ? -21.847 43.085 -24.685 1.00 328.00 ? 987 GLY A CA 1 ATOM 2103 C C . GLY A 1 271 ? -22.669 44.314 -24.996 1.00 329.43 ? 987 GLY A C 1 ATOM 2104 O O . GLY A 1 271 ? -22.480 45.343 -24.337 1.00 331.81 ? 987 GLY A O 1 ATOM 2105 N N . LYS A 1 272 ? -23.576 44.248 -25.969 1.00 333.08 ? 988 LYS A N 1 ATOM 2106 C CA . LYS A 1 272 ? -24.413 45.375 -26.358 1.00 331.54 ? 988 LYS A CA 1 ATOM 2107 C C . LYS A 1 272 ? -25.885 45.093 -26.070 1.00 330.64 ? 988 LYS A C 1 ATOM 2108 O O . LYS A 1 272 ? -26.761 45.380 -26.888 1.00 331.72 ? 988 LYS A O 1 ATOM 2109 C CB . LYS A 1 272 ? -24.228 45.713 -27.835 1.00 333.76 ? 988 LYS A CB 1 ATOM 2110 C CG . LYS A 1 272 ? -22.816 46.097 -28.236 1.00 337.51 ? 988 LYS A CG 1 ATOM 2111 C CD . LYS A 1 272 ? -22.789 46.527 -29.695 1.00 342.87 ? 988 LYS A CD 1 ATOM 2112 C CE . LYS A 1 272 ? -21.372 46.730 -30.199 1.00 345.75 ? 988 LYS A CE 1 ATOM 2113 N NZ . LYS A 1 272 ? -21.358 47.093 -31.644 1.00 347.78 ? 988 LYS A NZ 1 ATOM 2114 N N . GLY A 1 273 ? -26.176 44.523 -24.904 1.00 331.19 ? 989 GLY A N 1 ATOM 2115 C CA . GLY A 1 273 ? -27.552 44.234 -24.548 1.00 332.26 ? 989 GLY A CA 1 ATOM 2116 C C . GLY A 1 273 ? -27.699 43.390 -23.300 1.00 333.71 ? 989 GLY A C 1 ATOM 2117 O O . GLY A 1 273 ? -26.799 42.621 -22.951 1.00 333.05 ? 989 GLY A O 1 ATOM 2118 N N . ASP A 1 274 ? -28.832 43.531 -22.621 1.00 325.34 ? 990 ASP A N 1 ATOM 2119 C CA . ASP A 1 274 ? -29.128 42.774 -21.416 1.00 330.30 ? 990 ASP A CA 1 ATOM 2120 C C . ASP A 1 274 ? -29.959 41.545 -21.760 1.00 325.88 ? 990 ASP A C 1 ATOM 2121 O O . ASP A 1 274 ? -30.708 41.531 -22.741 1.00 323.36 ? 990 ASP A O 1 ATOM 2122 C CB . ASP A 1 274 ? -29.865 43.641 -20.394 1.00 337.32 ? 990 ASP A CB 1 ATOM 2123 C CG . ASP A 1 274 ? -29.017 44.795 -19.893 1.00 343.08 ? 990 ASP A CG 1 ATOM 2124 O OD1 . ASP A 1 274 ? -27.979 45.088 -20.522 1.00 342.40 ? 990 ASP A OD1 1 ATOM 2125 O OD2 . ASP A 1 274 ? -29.390 45.411 -18.872 1.00 352.75 ? 990 ASP A OD2 1 ATOM 2126 N N . VAL A 1 275 ? -29.820 40.512 -20.940 1.00 320.88 ? 991 VAL A N 1 ATOM 2127 C CA . VAL A 1 275 ? -30.439 39.220 -21.198 1.00 322.68 ? 991 VAL A CA 1 ATOM 2128 C C . VAL A 1 275 ? -31.647 39.059 -20.280 1.00 322.95 ? 991 VAL A C 1 ATOM 2129 O O . VAL A 1 275 ? -31.509 38.877 -19.067 1.00 323.27 ? 991 VAL A O 1 ATOM 2130 C CB . VAL A 1 275 ? -29.435 38.073 -21.016 1.00 325.05 ? 991 VAL A CB 1 ATOM 2131 C CG1 . VAL A 1 275 ? -28.681 38.229 -19.710 1.00 329.17 ? 991 VAL A CG1 1 ATOM 2132 C CG2 . VAL A 1 275 ? -30.134 36.720 -21.079 1.00 324.02 ? 991 VAL A CG2 1 ATOM 2133 N N . ILE A 1 276 ? -32.836 39.140 -20.861 1.00 334.16 ? 992 ILE A N 1 ATOM 2134 C CA . ILE A 1 276 ? -34.031 38.622 -20.214 1.00 335.62 ? 992 ILE A CA 1 ATOM 2135 C C . ILE A 1 276 ? -34.022 37.109 -20.394 1.00 337.75 ? 992 ILE A C 1 ATOM 2136 O O . ILE A 1 276 ? -33.356 36.585 -21.290 1.00 337.82 ? 992 ILE A O 1 ATOM 2137 C CB . ILE A 1 276 ? -35.312 39.275 -20.794 1.00 335.90 ? 992 ILE A CB 1 ATOM 2138 C CG1 . ILE A 1 276 ? -35.470 40.700 -20.274 1.00 336.52 ? 992 ILE A CG1 1 ATOM 2139 C CG2 . ILE A 1 276 ? -36.574 38.494 -20.445 1.00 336.61 ? 992 ILE A CG2 1 ATOM 2140 C CD1 . ILE A 1 276 ? -34.531 41.719 -20.882 1.00 337.22 ? 992 ILE A CD1 1 ATOM 2141 N N . ASP A 1 277 ? -34.691 36.391 -19.496 1.00 340.10 ? 993 ASP A N 1 ATOM 2142 C CA . ASP A 1 277 ? -34.756 34.940 -19.629 1.00 343.27 ? 993 ASP A CA 1 ATOM 2143 C C . ASP A 1 277 ? -35.201 34.559 -21.035 1.00 337.97 ? 993 ASP A C 1 ATOM 2144 O O . ASP A 1 277 ? -36.262 34.986 -21.505 1.00 342.06 ? 993 ASP A O 1 ATOM 2145 C CB . ASP A 1 277 ? -35.692 34.335 -18.574 1.00 351.38 ? 993 ASP A CB 1 ATOM 2146 C CG . ASP A 1 277 ? -36.979 35.118 -18.395 1.00 357.33 ? 993 ASP A CG 1 ATOM 2147 O OD1 . ASP A 1 277 ? -37.665 35.418 -19.392 1.00 361.36 ? 993 ASP A OD1 1 ATOM 2148 O OD2 . ASP A 1 277 ? -37.315 35.427 -17.233 1.00 360.63 ? 993 ASP A OD2 1 ATOM 2149 N N . ASP A 1 278 ? -34.335 33.822 -21.728 1.00 345.55 ? 994 ASP A N 1 ATOM 2150 C CA . ASP A 1 278 ? -34.525 33.192 -23.037 1.00 340.68 ? 994 ASP A CA 1 ATOM 2151 C C . ASP A 1 278 ? -34.195 34.098 -24.226 1.00 332.59 ? 994 ASP A C 1 ATOM 2152 O O . ASP A 1 278 ? -34.282 33.619 -25.360 1.00 327.28 ? 994 ASP A O 1 ATOM 2153 C CB . ASP A 1 278 ? -35.950 32.635 -23.223 1.00 346.34 ? 994 ASP A CB 1 ATOM 2154 C CG . ASP A 1 278 ? -35.995 31.427 -24.136 1.00 352.09 ? 994 ASP A CG 1 ATOM 2155 O OD1 . ASP A 1 278 ? -34.975 30.713 -24.234 1.00 357.43 ? 994 ASP A OD1 1 ATOM 2156 O OD2 . ASP A 1 278 ? -37.052 31.185 -24.754 1.00 360.20 ? 994 ASP A OD2 1 ATOM 2157 N N . TRP A 1 279 ? -33.812 35.361 -24.027 1.00 331.95 ? 995 TRP A N 1 ATOM 2158 C CA . TRP A 1 279 ? -33.532 36.228 -25.171 1.00 334.55 ? 995 TRP A CA 1 ATOM 2159 C C . TRP A 1 279 ? -32.748 37.457 -24.720 1.00 333.91 ? 995 TRP A C 1 ATOM 2160 O O . TRP A 1 279 ? -32.663 37.765 -23.529 1.00 331.27 ? 995 TRP A O 1 ATOM 2161 C CB . TRP A 1 279 ? -34.822 36.638 -25.889 1.00 336.99 ? 995 TRP A CB 1 ATOM 2162 C CG . TRP A 1 279 ? -35.879 37.187 -24.980 1.00 339.51 ? 995 TRP A CG 1 ATOM 2163 C CD1 . TRP A 1 279 ? -36.746 36.474 -24.204 1.00 340.73 ? 995 TRP A CD1 1 ATOM 2164 C CD2 . TRP A 1 279 ? -36.190 38.568 -24.764 1.00 341.29 ? 995 TRP A CD2 1 ATOM 2165 N NE1 . TRP A 1 279 ? -37.572 37.326 -23.512 1.00 340.65 ? 995 TRP A NE1 1 ATOM 2166 C CE2 . TRP A 1 279 ? -37.252 38.618 -23.840 1.00 340.67 ? 995 TRP A CE2 1 ATOM 2167 C CE3 . TRP A 1 279 ? -35.672 39.768 -25.261 1.00 342.43 ? 995 TRP A CE3 1 ATOM 2168 C CZ2 . TRP A 1 279 ? -37.805 39.819 -23.402 1.00 341.23 ? 995 TRP A CZ2 1 ATOM 2169 C CZ3 . TRP A 1 279 ? -36.221 40.958 -24.824 1.00 343.37 ? 995 TRP A CZ3 1 ATOM 2170 C CH2 . TRP A 1 279 ? -37.276 40.976 -23.904 1.00 342.84 ? 995 TRP A CH2 1 ATOM 2171 N N . CYS A 1 280 ? -32.177 38.161 -25.701 1.00 315.56 ? 996 CYS A N 1 ATOM 2172 C CA . CYS A 1 280 ? -31.397 39.370 -25.462 1.00 320.24 ? 996 CYS A CA 1 ATOM 2173 C C . CYS A 1 280 ? -32.223 40.605 -25.802 1.00 322.30 ? 996 CYS A C 1 ATOM 2174 O O . CYS A 1 280 ? -32.800 40.694 -26.890 1.00 326.71 ? 996 CYS A O 1 ATOM 2175 C CB . CYS A 1 280 ? -30.108 39.373 -26.289 1.00 322.64 ? 996 CYS A CB 1 ATOM 2176 S SG . CYS A 1 280 ? -28.801 38.241 -25.747 1.00 330.78 ? 996 CYS A SG 1 ATOM 2177 N N . ARG A 1 281 ? -32.265 41.555 -24.870 1.00 335.23 ? 997 ARG A N 1 ATOM 2178 C CA . ARG A 1 281 ? -32.901 42.858 -25.075 1.00 336.13 ? 997 ARG A CA 1 ATOM 2179 C C . ARG A 1 281 ? -31.816 43.820 -25.542 1.00 331.18 ? 997 ARG A C 1 ATOM 2180 O O . ARG A 1 281 ? -31.137 44.463 -24.739 1.00 330.32 ? 997 ARG A O 1 ATOM 2181 C CB . ARG A 1 281 ? -33.571 43.324 -23.788 1.00 340.53 ? 997 ARG A CB 1 ATOM 2182 C CG . ARG A 1 281 ? -34.179 44.719 -23.788 1.00 344.13 ? 997 ARG A CG 1 ATOM 2183 C CD . ARG A 1 281 ? -34.245 45.222 -22.348 1.00 348.45 ? 997 ARG A CD 1 ATOM 2184 N NE . ARG A 1 281 ? -35.376 46.105 -22.084 1.00 351.70 ? 997 ARG A NE 1 ATOM 2185 C CZ . ARG A 1 281 ? -35.654 46.613 -20.887 1.00 354.88 ? 997 ARG A CZ 1 ATOM 2186 N NH1 . ARG A 1 281 ? -36.702 47.408 -20.726 1.00 356.70 ? 997 ARG A NH1 1 ATOM 2187 N NH2 . ARG A 1 281 ? -34.880 46.326 -19.848 1.00 355.81 ? 997 ARG A NH2 1 ATOM 2188 N N . CYS A 1 282 ? -31.638 43.906 -26.859 1.00 332.64 ? 998 CYS A N 1 ATOM 2189 C CA . CYS A 1 282 ? -30.569 44.722 -27.424 1.00 339.35 ? 998 CYS A CA 1 ATOM 2190 C C . CYS A 1 282 ? -30.863 46.201 -27.204 1.00 338.61 ? 998 CYS A C 1 ATOM 2191 O O . CYS A 1 282 ? -31.922 46.697 -27.607 1.00 340.80 ? 998 CYS A O 1 ATOM 2192 C CB . CYS A 1 282 ? -30.400 44.433 -28.915 1.00 340.79 ? 998 CYS A CB 1 ATOM 2193 S SG . CYS A 1 282 ? -30.230 42.689 -29.398 1.00 348.76 ? 998 CYS A SG 1 ATOM 2194 N N . ASP A 1 283 ? -29.927 46.905 -26.571 1.00 342.12 ? 999 ASP A N 1 ATOM 2195 C CA . ASP A 1 283 ? -30.040 48.349 -26.422 1.00 345.54 ? 999 ASP A CA 1 ATOM 2196 C C . ASP A 1 283 ? -29.648 49.042 -27.721 1.00 344.74 ? 999 ASP A C 1 ATOM 2197 O O . ASP A 1 283 ? -28.711 48.624 -28.408 1.00 342.47 ? 999 ASP A O 1 ATOM 2198 C CB . ASP A 1 283 ? -29.164 48.849 -25.270 1.00 350.22 ? 999 ASP A CB 1 ATOM 2199 C CG . ASP A 1 283 ? -27.705 48.434 -25.408 1.00 352.18 ? 999 ASP A CG 1 ATOM 2200 O OD1 . ASP A 1 283 ? -26.980 49.035 -26.231 1.00 352.07 ? 999 ASP A OD1 1 ATOM 2201 O OD2 . ASP A 1 283 ? -27.279 47.514 -24.681 1.00 352.48 ? 999 ASP A OD2 1 ATOM 2202 N N . LEU A 1 284 ? -30.377 50.099 -28.061 1.00 342.41 ? 1000 LEU A N 1 ATOM 2203 C CA . LEU A 1 284 ? -30.071 50.860 -29.264 1.00 346.24 ? 1000 LEU A CA 1 ATOM 2204 C C . LEU A 1 284 ? -28.775 51.645 -29.078 1.00 352.10 ? 1000 LEU A C 1 ATOM 2205 O O . LEU A 1 284 ? -28.466 52.122 -27.984 1.00 358.16 ? 1000 LEU A O 1 ATOM 2206 C CB . LEU A 1 284 ? -31.235 51.796 -29.609 1.00 346.08 ? 1000 LEU A CB 1 ATOM 2207 C CG . LEU A 1 284 ? -31.756 52.775 -28.553 1.00 344.83 ? 1000 LEU A CG 1 ATOM 2208 C CD1 . LEU A 1 284 ? -30.995 54.096 -28.583 1.00 342.43 ? 1000 LEU A CD1 1 ATOM 2209 C CD2 . LEU A 1 284 ? -33.246 53.010 -28.746 1.00 346.66 ? 1000 LEU A CD2 1 ATOM 2210 N N . SER A 1 285 ? -28.008 51.774 -30.161 1.00 344.85 ? 1001 SER A N 1 ATOM 2211 C CA . SER A 1 285 ? -28.385 51.233 -31.463 1.00 347.92 ? 1001 SER A CA 1 ATOM 2212 C C . SER A 1 285 ? -27.543 50.025 -31.846 1.00 350.11 ? 1001 SER A C 1 ATOM 2213 O O . SER A 1 285 ? -26.653 50.118 -32.691 1.00 349.68 ? 1001 SER A O 1 ATOM 2214 C CB . SER A 1 285 ? -28.272 52.307 -32.545 1.00 352.20 ? 1001 SER A CB 1 ATOM 2215 O OG . SER A 1 285 ? -26.932 52.738 -32.698 1.00 357.44 ? 1001 SER A OG 1 ATOM 2216 N N . ALA A 1 286 ? -27.825 48.889 -31.211 1.00 344.38 ? 1002 ALA A N 1 ATOM 2217 C CA . ALA A 1 286 ? -27.256 47.636 -31.690 1.00 341.09 ? 1002 ALA A CA 1 ATOM 2218 C C . ALA A 1 286 ? -27.870 47.236 -33.023 1.00 335.13 ? 1002 ALA A C 1 ATOM 2219 O O . ALA A 1 286 ? -27.214 46.574 -33.831 1.00 335.25 ? 1002 ALA A O 1 ATOM 2220 C CB . ALA A 1 286 ? -27.459 46.530 -30.656 1.00 341.40 ? 1002 ALA A CB 1 ATOM 2221 N N . PHE A 1 287 ? -29.108 47.664 -33.274 1.00 342.70 ? 1003 PHE A N 1 ATOM 2222 C CA . PHE A 1 287 ? -29.856 47.266 -34.463 1.00 340.67 ? 1003 PHE A CA 1 ATOM 2223 C C . PHE A 1 287 ? -29.038 47.491 -35.728 1.00 335.67 ? 1003 PHE A C 1 ATOM 2224 O O . PHE A 1 287 ? -28.233 48.422 -35.818 1.00 330.22 ? 1003 PHE A O 1 ATOM 2225 C CB . PHE A 1 287 ? -31.173 48.046 -34.541 1.00 344.52 ? 1003 PHE A CB 1 ATOM 2226 C CG . PHE A 1 287 ? -32.058 47.870 -33.337 1.00 349.95 ? 1003 PHE A CG 1 ATOM 2227 C CD1 . PHE A 1 287 ? -33.014 46.868 -33.307 1.00 353.10 ? 1003 PHE A CD1 1 ATOM 2228 C CD2 . PHE A 1 287 ? -31.943 48.712 -32.241 1.00 350.69 ? 1003 PHE A CD2 1 ATOM 2229 C CE1 . PHE A 1 287 ? -33.835 46.704 -32.206 1.00 351.33 ? 1003 PHE A CE1 1 ATOM 2230 C CE2 . PHE A 1 287 ? -32.762 48.552 -31.136 1.00 350.40 ? 1003 PHE A CE2 1 ATOM 2231 C CZ . PHE A 1 287 ? -33.709 47.547 -31.120 1.00 349.17 ? 1003 PHE A CZ 1 ATOM 2232 N N . ASP A 1 288 ? -29.258 46.624 -36.719 1.00 333.67 ? 1004 ASP A N 1 ATOM 2233 C CA . ASP A 1 288 ? -28.441 46.628 -37.928 1.00 332.14 ? 1004 ASP A CA 1 ATOM 2234 C C . ASP A 1 288 ? -28.897 47.678 -38.933 1.00 331.25 ? 1004 ASP A C 1 ATOM 2235 O O . ASP A 1 288 ? -29.556 48.657 -38.568 1.00 331.39 ? 1004 ASP A O 1 ATOM 2236 C CB . ASP A 1 288 ? -28.432 45.237 -38.579 1.00 332.75 ? 1004 ASP A CB 1 ATOM 2237 C CG . ASP A 1 288 ? -29.825 44.744 -38.974 1.00 333.96 ? 1004 ASP A CG 1 ATOM 2238 O OD1 . ASP A 1 288 ? -30.723 45.567 -39.257 1.00 333.00 ? 1004 ASP A OD1 1 ATOM 2239 O OD2 . ASP A 1 288 ? -30.017 43.512 -39.014 1.00 332.45 ? 1004 ASP A OD2 1 ATOM 2240 N N . ALA A 1 289 ? -28.555 47.469 -40.205 1.00 331.73 ? 1005 ALA A N 1 ATOM 2241 C CA . ALA A 1 289 ? -28.889 48.444 -41.238 1.00 331.46 ? 1005 ALA A CA 1 ATOM 2242 C C . ALA A 1 289 ? -30.384 48.489 -41.515 1.00 331.95 ? 1005 ALA A C 1 ATOM 2243 O O . ALA A 1 289 ? -30.909 49.539 -41.901 1.00 331.27 ? 1005 ALA A O 1 ATOM 2244 C CB . ALA A 1 289 ? -28.122 48.132 -42.522 1.00 331.34 ? 1005 ALA A CB 1 ATOM 2245 N N . ASN A 1 290 ? -31.081 47.373 -41.334 1.00 332.22 ? 1006 ASN A N 1 ATOM 2246 C CA . ASN A 1 290 ? -32.520 47.322 -41.540 1.00 333.10 ? 1006 ASN A CA 1 ATOM 2247 C C . ASN A 1 290 ? -33.308 47.526 -40.252 1.00 332.18 ? 1006 ASN A C 1 ATOM 2248 O O . ASN A 1 290 ? -34.532 47.366 -40.258 1.00 334.65 ? 1006 ASN A O 1 ATOM 2249 C CB . ASN A 1 290 ? -32.919 45.991 -42.185 1.00 335.01 ? 1006 ASN A CB 1 ATOM 2250 C CG . ASN A 1 290 ? -32.291 45.794 -43.552 1.00 337.37 ? 1006 ASN A CG 1 ATOM 2251 O OD1 . ASN A 1 290 ? -32.655 46.464 -44.519 1.00 339.99 ? 1006 ASN A OD1 1 ATOM 2252 N ND2 . ASN A 1 290 ? -31.352 44.861 -43.641 1.00 338.87 ? 1006 ASN A ND2 1 ATOM 2253 N N . GLY A 1 291 ? -32.640 47.871 -39.157 1.00 339.51 ? 1007 GLY A N 1 ATOM 2254 C CA . GLY A 1 291 ? -33.331 48.114 -37.904 1.00 337.38 ? 1007 GLY A CA 1 ATOM 2255 C C . GLY A 1 291 ? -33.796 46.869 -37.184 1.00 336.80 ? 1007 GLY A C 1 ATOM 2256 O O . GLY A 1 291 ? -34.873 46.874 -36.575 1.00 337.58 ? 1007 GLY A O 1 ATOM 2257 N N . LEU A 1 292 ? -33.012 45.792 -37.233 1.00 346.78 ? 1008 LEU A N 1 ATOM 2258 C CA . LEU A 1 292 ? -33.355 44.549 -36.568 1.00 343.09 ? 1008 LEU A CA 1 ATOM 2259 C C . LEU A 1 292 ? -32.348 44.248 -35.465 1.00 340.85 ? 1008 LEU A C 1 ATOM 2260 O O . LEU A 1 292 ? -31.158 44.550 -35.621 1.00 337.71 ? 1008 LEU A O 1 ATOM 2261 C CB . LEU A 1 292 ? -33.396 43.386 -37.571 1.00 340.64 ? 1008 LEU A CB 1 ATOM 2262 C CG . LEU A 1 292 ? -34.280 43.614 -38.802 1.00 339.86 ? 1008 LEU A CG 1 ATOM 2263 C CD1 . LEU A 1 292 ? -34.251 42.407 -39.728 1.00 340.24 ? 1008 LEU A CD1 1 ATOM 2264 C CD2 . LEU A 1 292 ? -35.707 43.946 -38.390 1.00 340.94 ? 1008 LEU A CD2 1 ATOM 2265 N N . PRO A 1 293 ? -32.787 43.668 -34.346 1.00 335.63 ? 1009 PRO A N 1 ATOM 2266 C CA . PRO A 1 293 ? -31.879 43.442 -33.211 1.00 335.03 ? 1009 PRO A CA 1 ATOM 2267 C C . PRO A 1 293 ? -30.643 42.652 -33.618 1.00 335.42 ? 1009 PRO A C 1 ATOM 2268 O O . PRO A 1 293 ? -30.732 41.605 -34.258 1.00 334.22 ? 1009 PRO A O 1 ATOM 2269 C CB . PRO A 1 293 ? -32.747 42.663 -32.218 1.00 337.25 ? 1009 PRO A CB 1 ATOM 2270 C CG . PRO A 1 293 ? -34.146 43.068 -32.551 1.00 337.34 ? 1009 PRO A CG 1 ATOM 2271 C CD . PRO A 1 293 ? -34.171 43.275 -34.038 1.00 336.62 ? 1009 PRO A CD 1 ATOM 2272 N N . ASN A 1 294 ? -29.475 43.169 -33.234 1.00 338.68 ? 1010 ASN A N 1 ATOM 2273 C CA . ASN A 1 294 ? -28.207 42.669 -33.745 1.00 336.76 ? 1010 ASN A CA 1 ATOM 2274 C C . ASN A 1 294 ? -27.220 42.319 -32.638 1.00 331.17 ? 1010 ASN A C 1 ATOM 2275 O O . ASN A 1 294 ? -26.065 41.991 -32.940 1.00 329.54 ? 1010 ASN A O 1 ATOM 2276 C CB . ASN A 1 294 ? -27.594 43.708 -34.698 1.00 337.94 ? 1010 ASN A CB 1 ATOM 2277 C CG . ASN A 1 294 ? -26.725 43.089 -35.776 1.00 342.79 ? 1010 ASN A CG 1 ATOM 2278 O OD1 . ASN A 1 294 ? -26.790 41.886 -36.033 1.00 347.62 ? 1010 ASN A OD1 1 ATOM 2279 N ND2 . ASN A 1 294 ? -25.914 43.918 -36.425 1.00 347.47 ? 1010 ASN A ND2 1 ATOM 2280 N N . CYS A 1 295 ? -27.637 42.366 -31.372 1.00 334.75 ? 1011 CYS A N 1 ATOM 2281 C CA . CYS A 1 295 ? -26.687 42.136 -30.288 1.00 336.04 ? 1011 CYS A CA 1 ATOM 2282 C C . CYS A 1 295 ? -26.354 40.655 -30.131 1.00 334.84 ? 1011 CYS A C 1 ATOM 2283 O O . CYS A 1 295 ? -25.194 40.304 -29.896 1.00 342.83 ? 1011 CYS A O 1 ATOM 2284 C CB . CYS A 1 295 ? -27.213 42.728 -28.978 1.00 339.55 ? 1011 CYS A CB 1 ATOM 2285 S SG . CYS A 1 295 ? -28.697 41.975 -28.273 1.00 344.82 ? 1011 CYS A SG 1 ATOM 2286 N N . SER A 1 296 ? -27.336 39.774 -30.271 1.00 338.13 ? 1012 SER A N 1 ATOM 2287 C CA . SER A 1 296 ? -27.029 38.346 -30.265 1.00 337.66 ? 1012 SER A CA 1 ATOM 2288 C C . SER A 1 296 ? -26.618 37.905 -31.666 1.00 339.20 ? 1012 SER A C 1 ATOM 2289 O O . SER A 1 296 ? -27.316 38.221 -32.635 1.00 337.60 ? 1012 SER A O 1 ATOM 2290 C CB . SER A 1 296 ? -28.225 37.531 -29.787 1.00 337.17 ? 1012 SER A CB 1 ATOM 2291 O OG . SER A 1 296 ? -27.927 36.145 -29.792 1.00 336.82 ? 1012 SER A OG 1 ATOM 2292 N N . PRO A 1 297 ? -25.508 37.183 -31.815 1.00 343.11 ? 1013 PRO A N 1 ATOM 2293 C CA . PRO A 1 297 ? -25.019 36.848 -33.158 1.00 343.54 ? 1013 PRO A CA 1 ATOM 2294 C C . PRO A 1 297 ? -25.800 35.710 -33.797 1.00 342.94 ? 1013 PRO A C 1 ATOM 2295 O O . PRO A 1 297 ? -26.147 34.719 -33.149 1.00 341.72 ? 1013 PRO A O 1 ATOM 2296 C CB . PRO A 1 297 ? -23.561 36.445 -32.905 1.00 344.44 ? 1013 PRO A CB 1 ATOM 2297 C CG . PRO A 1 297 ? -23.571 35.902 -31.517 1.00 344.67 ? 1013 PRO A CG 1 ATOM 2298 C CD . PRO A 1 297 ? -24.599 36.705 -30.757 1.00 344.70 ? 1013 PRO A CD 1 ATOM 2299 N N . LEU A 1 298 ? -26.074 35.867 -35.092 1.00 339.28 ? 1014 LEU A N 1 ATOM 2300 C CA . LEU A 1 298 ? -26.694 34.830 -35.908 1.00 337.12 ? 1014 LEU A CA 1 ATOM 2301 C C . LEU A 1 298 ? -25.589 34.211 -36.757 1.00 336.75 ? 1014 LEU A C 1 ATOM 2302 O O . LEU A 1 298 ? -25.128 34.812 -37.730 1.00 335.13 ? 1014 LEU A O 1 ATOM 2303 C CB . LEU A 1 298 ? -27.812 35.417 -36.770 1.00 337.77 ? 1014 LEU A CB 1 ATOM 2304 C CG . LEU A 1 298 ? -28.486 34.491 -37.785 1.00 339.35 ? 1014 LEU A CG 1 ATOM 2305 C CD1 . LEU A 1 298 ? -29.224 33.359 -37.088 1.00 339.12 ? 1014 LEU A CD1 1 ATOM 2306 C CD2 . LEU A 1 298 ? -29.429 35.276 -38.688 1.00 340.28 ? 1014 LEU A CD2 1 ATOM 2307 N N . LEU A 1 299 ? -25.163 33.007 -36.381 1.00 335.08 ? 1015 LEU A N 1 ATOM 2308 C CA . LEU A 1 299 ? -23.969 32.407 -36.954 1.00 335.18 ? 1015 LEU A CA 1 ATOM 2309 C C . LEU A 1 299 ? -24.245 31.830 -38.340 1.00 332.23 ? 1015 LEU A C 1 ATOM 2310 O O . LEU A 1 299 ? -25.388 31.571 -38.722 1.00 332.94 ? 1015 LEU A O 1 ATOM 2311 C CB . LEU A 1 299 ? -23.425 31.314 -36.035 1.00 336.45 ? 1015 LEU A CB 1 ATOM 2312 C CG . LEU A 1 299 ? -23.019 31.749 -34.627 1.00 336.82 ? 1015 LEU A CG 1 ATOM 2313 C CD1 . LEU A 1 299 ? -22.494 30.564 -33.834 1.00 337.91 ? 1015 LEU A CD1 1 ATOM 2314 C CD2 . LEU A 1 299 ? -21.984 32.862 -34.688 1.00 337.36 ? 1015 LEU A CD2 1 ATOM 2315 N N . GLN A 1 300 ? -23.166 31.626 -39.085 1.00 320.68 ? 1016 GLN A N 1 ATOM 2316 C CA . GLN A 1 300 ? -23.248 31.026 -40.412 1.00 321.17 ? 1016 GLN A CA 1 ATOM 2317 C C . GLN A 1 300 ? -23.448 29.519 -40.291 1.00 321.08 ? 1016 GLN A C 1 ATOM 2318 O O . GLN A 1 300 ? -22.636 28.847 -39.647 1.00 327.32 ? 1016 GLN A O 1 ATOM 2319 C CB . GLN A 1 300 ? -21.980 31.321 -41.205 1.00 324.58 ? 1016 GLN A CB 1 ATOM 2320 C CG . GLN A 1 300 ? -21.910 30.637 -42.562 1.00 328.05 ? 1016 GLN A CG 1 ATOM 2321 C CD . GLN A 1 300 ? -20.501 30.611 -43.124 1.00 332.72 ? 1016 GLN A CD 1 ATOM 2322 O OE1 . GLN A 1 300 ? -19.611 29.970 -42.565 1.00 339.13 ? 1016 GLN A OE1 1 ATOM 2323 N NE2 . GLN A 1 300 ? -20.290 31.313 -44.232 1.00 335.20 ? 1016 GLN A NE2 1 ATOM 2324 N N . PRO A 1 301 ? -24.503 28.954 -40.883 1.00 315.37 ? 1017 PRO A N 1 ATOM 2325 C CA . PRO A 1 301 ? -24.683 27.494 -40.862 1.00 314.19 ? 1017 PRO A CA 1 ATOM 2326 C C . PRO A 1 301 ? -23.811 26.835 -41.921 1.00 313.03 ? 1017 PRO A C 1 ATOM 2327 O O . PRO A 1 301 ? -23.945 27.120 -43.112 1.00 315.50 ? 1017 PRO A O 1 ATOM 2328 C CB . PRO A 1 301 ? -26.174 27.318 -41.168 1.00 315.19 ? 1017 PRO A CB 1 ATOM 2329 C CG . PRO A 1 301 ? -26.525 28.519 -41.987 1.00 314.52 ? 1017 PRO A CG 1 ATOM 2330 C CD . PRO A 1 301 ? -25.649 29.648 -41.499 1.00 314.14 ? 1017 PRO A CD 1 ATOM 2331 N N . VAL A 1 302 ? -22.925 25.943 -41.488 1.00 326.30 ? 1018 VAL A N 1 ATOM 2332 C CA . VAL A 1 302 ? -21.970 25.295 -42.381 1.00 320.82 ? 1018 VAL A CA 1 ATOM 2333 C C . VAL A 1 302 ? -22.665 24.121 -43.064 1.00 317.71 ? 1018 VAL A C 1 ATOM 2334 O O . VAL A 1 302 ? -22.967 23.108 -42.427 1.00 320.41 ? 1018 VAL A O 1 ATOM 2335 C CB . VAL A 1 302 ? -20.716 24.839 -41.625 1.00 321.03 ? 1018 VAL A CB 1 ATOM 2336 C CG1 . VAL A 1 302 ? -19.815 24.028 -42.540 1.00 322.56 ? 1018 VAL A CG1 1 ATOM 2337 C CG2 . VAL A 1 302 ? -19.967 26.042 -41.068 1.00 320.72 ? 1018 VAL A CG2 1 ATOM 2338 N N . LEU A 1 303 ? -22.917 24.259 -44.363 1.00 299.42 ? 1019 LEU A N 1 ATOM 2339 C CA . LEU A 1 303 ? -23.544 23.199 -45.142 1.00 301.15 ? 1019 LEU A CA 1 ATOM 2340 C C . LEU A 1 303 ? -22.524 22.107 -45.442 1.00 302.86 ? 1019 LEU A C 1 ATOM 2341 O O . LEU A 1 303 ? -21.414 22.391 -45.906 1.00 300.78 ? 1019 LEU A O 1 ATOM 2342 C CB . LEU A 1 303 ? -24.119 23.767 -46.438 1.00 301.00 ? 1019 LEU A CB 1 ATOM 2343 C CG . LEU A 1 303 ? -24.892 22.822 -47.358 1.00 302.21 ? 1019 LEU A CG 1 ATOM 2344 C CD1 . LEU A 1 303 ? -26.163 22.339 -46.682 1.00 302.12 ? 1019 LEU A CD1 1 ATOM 2345 C CD2 . LEU A 1 303 ? -25.209 23.516 -48.673 1.00 303.89 ? 1019 LEU A CD2 1 ATOM 2346 N N . ARG A 1 304 ? -22.899 20.859 -45.176 1.00 292.79 ? 1020 ARG A N 1 ATOM 2347 C CA . ARG A 1 304 ? -21.999 19.726 -45.322 1.00 296.79 ? 1020 ARG A CA 1 ATOM 2348 C C . ARG A 1 304 ? -22.642 18.641 -46.171 1.00 295.17 ? 1020 ARG A C 1 ATOM 2349 O O . ARG A 1 304 ? -23.867 18.508 -46.217 1.00 293.00 ? 1020 ARG A O 1 ATOM 2350 C CB . ARG A 1 304 ? -21.621 19.134 -43.952 1.00 304.20 ? 1020 ARG A CB 1 ATOM 2351 C CG . ARG A 1 304 ? -20.224 19.487 -43.470 1.00 312.60 ? 1020 ARG A CG 1 ATOM 2352 C CD . ARG A 1 304 ? -19.931 18.882 -42.103 1.00 319.58 ? 1020 ARG A CD 1 ATOM 2353 N NE . ARG A 1 304 ? -20.253 19.800 -41.015 1.00 322.70 ? 1020 ARG A NE 1 ATOM 2354 C CZ . ARG A 1 304 ? -19.428 20.744 -40.573 1.00 323.07 ? 1020 ARG A CZ 1 ATOM 2355 N NH1 . ARG A 1 304 ? -18.234 20.893 -41.130 1.00 319.22 ? 1020 ARG A NH1 1 ATOM 2356 N NH2 . ARG A 1 304 ? -19.795 21.539 -39.576 1.00 323.45 ? 1020 ARG A NH2 1 ATOM 2357 N N . LEU A 1 305 ? -21.798 17.869 -46.847 1.00 302.35 ? 1021 LEU A N 1 ATOM 2358 C CA . LEU A 1 305 ? -22.242 16.598 -47.393 1.00 302.13 ? 1021 LEU A CA 1 ATOM 2359 C C . LEU A 1 305 ? -22.416 15.595 -46.261 1.00 304.38 ? 1021 LEU A C 1 ATOM 2360 O O . LEU A 1 305 ? -21.703 15.633 -45.254 1.00 306.35 ? 1021 LEU A O 1 ATOM 2361 C CB . LEU A 1 305 ? -21.236 16.059 -48.407 1.00 302.09 ? 1021 LEU A CB 1 ATOM 2362 C CG . LEU A 1 305 ? -21.447 16.332 -49.895 1.00 303.12 ? 1021 LEU A CG 1 ATOM 2363 C CD1 . LEU A 1 305 ? -20.402 15.571 -50.688 1.00 302.89 ? 1021 LEU A CD1 1 ATOM 2364 C CD2 . LEU A 1 305 ? -22.846 15.926 -50.332 1.00 304.76 ? 1021 LEU A CD2 1 ATOM 2365 N N . SER A 1 306 ? -23.376 14.697 -46.426 1.00 303.69 ? 1022 SER A N 1 ATOM 2366 C CA . SER A 1 306 ? -23.614 13.678 -45.417 1.00 304.59 ? 1022 SER A CA 1 ATOM 2367 C C . SER A 1 306 ? -22.408 12.754 -45.323 1.00 303.20 ? 1022 SER A C 1 ATOM 2368 O O . SER A 1 306 ? -21.991 12.187 -46.344 1.00 302.81 ? 1022 SER A O 1 ATOM 2369 C CB . SER A 1 306 ? -24.866 12.876 -45.744 1.00 306.41 ? 1022 SER A CB 1 ATOM 2370 O OG . SER A 1 306 ? -25.061 11.839 -44.799 1.00 310.62 ? 1022 SER A OG 1 ATOM 2371 N N . PRO A 1 307 ? -21.813 12.584 -44.141 1.00 291.90 ? 1023 PRO A N 1 ATOM 2372 C CA . PRO A 1 307 ? -20.656 11.683 -44.028 1.00 293.01 ? 1023 PRO A CA 1 ATOM 2373 C C . PRO A 1 307 ? -20.991 10.232 -44.324 1.00 295.35 ? 1023 PRO A C 1 ATOM 2374 O O . PRO A 1 307 ? -20.109 9.477 -44.752 1.00 295.11 ? 1023 PRO A O 1 ATOM 2375 C CB . PRO A 1 307 ? -20.209 11.870 -42.571 1.00 293.04 ? 1023 PRO A CB 1 ATOM 2376 C CG . PRO A 1 307 ? -20.790 13.188 -42.150 1.00 293.25 ? 1023 PRO A CG 1 ATOM 2377 C CD . PRO A 1 307 ? -22.086 13.304 -42.886 1.00 292.25 ? 1023 PRO A CD 1 ATOM 2378 N N . THR A 1 308 ? -22.241 9.822 -44.120 1.00 291.48 ? 1024 THR A N 1 ATOM 2379 C CA . THR A 1 308 ? -22.632 8.425 -44.254 1.00 293.01 ? 1024 THR A CA 1 ATOM 2380 C C . THR A 1 308 ? -23.142 8.067 -45.643 1.00 294.89 ? 1024 THR A C 1 ATOM 2381 O O . THR A 1 308 ? -23.261 6.877 -45.951 1.00 299.22 ? 1024 THR A O 1 ATOM 2382 C CB . THR A 1 308 ? -23.714 8.079 -43.225 1.00 294.02 ? 1024 THR A CB 1 ATOM 2383 O OG1 . THR A 1 308 ? -24.872 8.891 -43.457 1.00 296.92 ? 1024 THR A OG1 1 ATOM 2384 C CG2 . THR A 1 308 ? -23.205 8.324 -41.813 1.00 295.36 ? 1024 THR A CG2 1 ATOM 2385 N N . VAL A 1 309 ? -23.448 9.053 -46.482 1.00 293.89 ? 1025 VAL A N 1 ATOM 2386 C CA . VAL A 1 309 ? -24.083 8.820 -47.775 1.00 296.36 ? 1025 VAL A CA 1 ATOM 2387 C C . VAL A 1 309 ? -23.267 9.548 -48.836 1.00 296.41 ? 1025 VAL A C 1 ATOM 2388 O O . VAL A 1 309 ? -23.435 10.756 -49.039 1.00 300.64 ? 1025 VAL A O 1 ATOM 2389 C CB . VAL A 1 309 ? -25.544 9.281 -47.797 1.00 297.91 ? 1025 VAL A CB 1 ATOM 2390 C CG1 . VAL A 1 309 ? -26.143 9.026 -49.160 1.00 296.35 ? 1025 VAL A CG1 1 ATOM 2391 C CG2 . VAL A 1 309 ? -26.349 8.571 -46.718 1.00 299.23 ? 1025 VAL A CG2 1 ATOM 2392 N N . GLU A 1 310 ? -22.396 8.819 -49.520 1.00 305.87 ? 1026 GLU A N 1 ATOM 2393 C CA . GLU A 1 310 ? -21.672 9.388 -50.647 1.00 306.35 ? 1026 GLU A CA 1 ATOM 2394 C C . GLU A 1 310 ? -22.647 9.695 -51.778 1.00 299.70 ? 1026 GLU A C 1 ATOM 2395 O O . GLU A 1 310 ? -23.488 8.851 -52.111 1.00 299.32 ? 1026 GLU A O 1 ATOM 2396 C CB . GLU A 1 310 ? -20.587 8.428 -51.130 1.00 311.39 ? 1026 GLU A CB 1 ATOM 2397 C CG . GLU A 1 310 ? -19.246 8.594 -50.430 1.00 316.79 ? 1026 GLU A CG 1 ATOM 2398 C CD . GLU A 1 310 ? -18.341 7.390 -50.613 1.00 324.47 ? 1026 GLU A CD 1 ATOM 2399 O OE1 . GLU A 1 310 ? -17.755 6.931 -49.609 1.00 331.89 ? 1026 GLU A OE1 1 ATOM 2400 O OE2 . GLU A 1 310 ? -18.226 6.893 -51.755 1.00 324.09 ? 1026 GLU A OE2 1 ATOM 2401 N N . PRO A 1 311 ? -22.578 10.879 -52.382 1.00 300.20 ? 1027 PRO A N 1 ATOM 2402 C CA . PRO A 1 311 ? -23.521 11.206 -53.455 1.00 300.24 ? 1027 PRO A CA 1 ATOM 2403 C C . PRO A 1 311 ? -23.312 10.320 -54.673 1.00 298.49 ? 1027 PRO A C 1 ATOM 2404 O O . PRO A 1 311 ? -22.185 10.105 -55.126 1.00 297.99 ? 1027 PRO A O 1 ATOM 2405 C CB . PRO A 1 311 ? -23.216 12.679 -53.764 1.00 300.53 ? 1027 PRO A CB 1 ATOM 2406 C CG . PRO A 1 311 ? -21.837 12.906 -53.250 1.00 300.32 ? 1027 PRO A CG 1 ATOM 2407 C CD . PRO A 1 311 ? -21.693 12.010 -52.056 1.00 300.33 ? 1027 PRO A CD 1 ATOM 2408 N N . SER A 1 312 ? -24.414 9.791 -55.186 1.00 311.33 ? 1028 SER A N 1 ATOM 2409 C CA . SER A 1 312 ? -24.441 9.074 -56.448 1.00 311.73 ? 1028 SER A CA 1 ATOM 2410 C C . SER A 1 312 ? -25.064 9.971 -57.503 1.00 311.76 ? 1028 SER A C 1 ATOM 2411 O O . SER A 1 312 ? -25.718 10.969 -57.186 1.00 313.18 ? 1028 SER A O 1 ATOM 2412 C CB . SER A 1 312 ? -25.232 7.767 -56.332 1.00 311.41 ? 1028 SER A CB 1 ATOM 2413 O OG . SER A 1 312 ? -26.600 8.021 -56.059 1.00 313.27 ? 1028 SER A OG 1 ATOM 2414 N N . SER A 1 313 ? -24.847 9.619 -58.767 1.00 306.38 ? 1029 SER A N 1 ATOM 2415 C CA . SER A 1 313 ? -25.485 10.358 -59.845 1.00 307.96 ? 1029 SER A CA 1 ATOM 2416 C C . SER A 1 313 ? -26.986 10.391 -59.618 1.00 311.43 ? 1029 SER A C 1 ATOM 2417 O O . SER A 1 313 ? -27.594 9.375 -59.263 1.00 318.92 ? 1029 SER A O 1 ATOM 2418 C CB . SER A 1 313 ? -25.162 9.712 -61.191 1.00 307.22 ? 1029 SER A CB 1 ATOM 2419 O OG . SER A 1 313 ? -25.800 8.456 -61.306 1.00 305.93 ? 1029 SER A OG 1 ATOM 2420 N N . THR A 1 314 ? -27.572 11.578 -59.790 1.00 314.23 ? 1030 THR A N 1 ATOM 2421 C CA . THR A 1 314 ? -28.982 11.911 -59.581 1.00 314.93 ? 1030 THR A CA 1 ATOM 2422 C C . THR A 1 314 ? -29.359 12.055 -58.104 1.00 313.04 ? 1030 THR A C 1 ATOM 2423 O O . THR A 1 314 ? -30.540 12.283 -57.814 1.00 318.17 ? 1030 THR A O 1 ATOM 2424 C CB . THR A 1 314 ? -29.955 10.903 -60.217 1.00 314.06 ? 1030 THR A CB 1 ATOM 2425 O OG1 . THR A 1 314 ? -29.929 9.670 -59.478 1.00 309.80 ? 1030 THR A OG1 1 ATOM 2426 C CG2 . THR A 1 314 ? -29.603 10.622 -61.681 1.00 316.07 ? 1030 THR A CG2 1 ATOM 2427 N N . VAL A 1 315 ? -28.414 11.928 -57.163 1.00 308.75 ? 1031 VAL A N 1 ATOM 2428 C CA . VAL A 1 315 ? -28.728 11.936 -55.735 1.00 307.98 ? 1031 VAL A CA 1 ATOM 2429 C C . VAL A 1 315 ? -27.654 12.690 -54.957 1.00 303.71 ? 1031 VAL A C 1 ATOM 2430 O O . VAL A 1 315 ? -26.453 12.502 -55.190 1.00 302.22 ? 1031 VAL A O 1 ATOM 2431 C CB . VAL A 1 315 ? -28.859 10.508 -55.155 1.00 308.44 ? 1031 VAL A CB 1 ATOM 2432 C CG1 . VAL A 1 315 ? -29.343 10.573 -53.715 1.00 306.25 ? 1031 VAL A CG1 1 ATOM 2433 C CG2 . VAL A 1 315 ? -29.795 9.650 -55.982 1.00 311.67 ? 1031 VAL A CG2 1 ATOM 2434 N N . VAL A 1 316 ? -28.091 13.522 -54.016 1.00 300.38 ? 1032 VAL A N 1 ATOM 2435 C CA . VAL A 1 316 ? -27.215 14.189 -53.049 1.00 300.17 ? 1032 VAL A CA 1 ATOM 2436 C C . VAL A 1 316 ? -28.009 14.363 -51.755 1.00 301.41 ? 1032 VAL A C 1 ATOM 2437 O O . VAL A 1 316 ? -29.201 14.664 -51.786 1.00 299.68 ? 1032 VAL A O 1 ATOM 2438 C CB . VAL A 1 316 ? -26.702 15.554 -53.555 1.00 299.62 ? 1032 VAL A CB 1 ATOM 2439 C CG1 . VAL A 1 316 ? -26.024 16.321 -52.432 1.00 298.88 ? 1032 VAL A CG1 1 ATOM 2440 C CG2 . VAL A 1 316 ? -25.724 15.395 -54.711 1.00 301.27 ? 1032 VAL A CG2 1 ATOM 2441 N N . SER A 1 317 ? -27.347 14.164 -50.615 1.00 280.66 ? 1033 SER A N 1 ATOM 2442 C CA . SER A 1 317 ? -27.941 14.425 -49.310 1.00 282.01 ? 1033 SER A CA 1 ATOM 2443 C C . SER A 1 317 ? -26.991 15.295 -48.499 1.00 278.52 ? 1033 SER A C 1 ATOM 2444 O O . SER A 1 317 ? -25.789 15.016 -48.436 1.00 280.40 ? 1033 SER A O 1 ATOM 2445 C CB . SER A 1 317 ? -28.253 13.122 -48.558 1.00 284.96 ? 1033 SER A CB 1 ATOM 2446 O OG . SER A 1 317 ? -27.134 12.674 -47.824 1.00 287.06 ? 1033 SER A OG 1 ATOM 2447 N N . LEU A 1 318 ? -27.529 16.351 -47.890 1.00 287.09 ? 1034 LEU A N 1 ATOM 2448 C CA . LEU A 1 318 ? -26.745 17.376 -47.216 1.00 288.41 ? 1034 LEU A CA 1 ATOM 2449 C C . LEU A 1 318 ? -27.134 17.479 -45.746 1.00 287.12 ? 1034 LEU A C 1 ATOM 2450 O O . LEU A 1 318 ? -28.218 17.056 -45.339 1.00 288.05 ? 1034 LEU A O 1 ATOM 2451 C CB . LEU A 1 318 ? -26.934 18.739 -47.899 1.00 287.90 ? 1034 LEU A CB 1 ATOM 2452 C CG . LEU A 1 318 ? -26.645 18.783 -49.400 1.00 286.57 ? 1034 LEU A CG 1 ATOM 2453 C CD1 . LEU A 1 318 ? -27.104 20.103 -50.001 1.00 286.92 ? 1034 LEU A CD1 1 ATOM 2454 C CD2 . LEU A 1 318 ? -25.166 18.568 -49.654 1.00 287.63 ? 1034 LEU A CD2 1 ATOM 2455 N N . GLU A 1 319 ? -26.233 18.063 -44.954 1.00 295.06 ? 1035 GLU A N 1 ATOM 2456 C CA . GLU A 1 319 ? -26.423 18.239 -43.520 1.00 297.65 ? 1035 GLU A CA 1 ATOM 2457 C C . GLU A 1 319 ? -26.017 19.645 -43.101 1.00 295.42 ? 1035 GLU A C 1 ATOM 2458 O O . GLU A 1 319 ? -25.309 20.348 -43.824 1.00 296.71 ? 1035 GLU A O 1 ATOM 2459 C CB . GLU A 1 319 ? -25.592 17.235 -42.702 1.00 300.72 ? 1035 GLU A CB 1 ATOM 2460 C CG . GLU A 1 319 ? -26.081 15.804 -42.709 1.00 304.63 ? 1035 GLU A CG 1 ATOM 2461 C CD . GLU A 1 319 ? -25.281 14.930 -41.761 1.00 308.82 ? 1035 GLU A CD 1 ATOM 2462 O OE1 . GLU A 1 319 ? -24.351 15.455 -41.110 1.00 311.70 ? 1035 GLU A OE1 1 ATOM 2463 O OE2 . GLU A 1 319 ? -25.580 13.721 -41.663 1.00 315.83 ? 1035 GLU A OE2 1 ATOM 2464 N N . TRP A 1 320 ? -26.475 20.040 -41.914 1.00 296.86 ? 1036 TRP A N 1 ATOM 2465 C CA . TRP A 1 320 ? -25.932 21.196 -41.210 1.00 296.46 ? 1036 TRP A CA 1 ATOM 2466 C C . TRP A 1 320 ? -26.437 21.182 -39.774 1.00 297.81 ? 1036 TRP A C 1 ATOM 2467 O O . TRP A 1 320 ? -27.517 20.660 -39.488 1.00 298.85 ? 1036 TRP A O 1 ATOM 2468 C CB . TRP A 1 320 ? -26.287 22.527 -41.895 1.00 295.16 ? 1036 TRP A CB 1 ATOM 2469 C CG . TRP A 1 320 ? -27.735 22.922 -41.864 1.00 294.97 ? 1036 TRP A CG 1 ATOM 2470 C CD1 . TRP A 1 320 ? -28.368 23.652 -40.897 1.00 294.17 ? 1036 TRP A CD1 1 ATOM 2471 C CD2 . TRP A 1 320 ? -28.719 22.646 -42.866 1.00 294.60 ? 1036 TRP A CD2 1 ATOM 2472 N NE1 . TRP A 1 320 ? -29.690 23.832 -41.231 1.00 293.46 ? 1036 TRP A NE1 1 ATOM 2473 C CE2 . TRP A 1 320 ? -29.929 23.227 -42.436 1.00 293.73 ? 1036 TRP A CE2 1 ATOM 2474 C CE3 . TRP A 1 320 ? -28.696 21.959 -44.083 1.00 294.79 ? 1036 TRP A CE3 1 ATOM 2475 C CZ2 . TRP A 1 320 ? -31.106 23.136 -43.177 1.00 294.03 ? 1036 TRP A CZ2 1 ATOM 2476 C CZ3 . TRP A 1 320 ? -29.864 21.871 -44.819 1.00 294.25 ? 1036 TRP A CZ3 1 ATOM 2477 C CH2 . TRP A 1 320 ? -31.053 22.456 -44.363 1.00 294.46 ? 1036 TRP A CH2 1 ATOM 2478 N N . VAL A 1 321 ? -25.632 21.749 -38.877 1.00 294.69 ? 1037 VAL A N 1 ATOM 2479 C CA . VAL A 1 321 ? -25.932 21.793 -37.450 1.00 297.54 ? 1037 VAL A CA 1 ATOM 2480 C C . VAL A 1 321 ? -26.585 23.131 -37.131 1.00 299.14 ? 1037 VAL A C 1 ATOM 2481 O O . VAL A 1 321 ? -26.183 24.171 -37.665 1.00 299.57 ? 1037 VAL A O 1 ATOM 2482 C CB . VAL A 1 321 ? -24.657 21.565 -36.611 1.00 296.58 ? 1037 VAL A CB 1 ATOM 2483 C CG1 . VAL A 1 321 ? -23.523 22.467 -37.088 1.00 298.55 ? 1037 VAL A CG1 1 ATOM 2484 C CG2 . VAL A 1 321 ? -24.934 21.779 -35.124 1.00 298.33 ? 1037 VAL A CG2 1 ATOM 2485 N N . ASP A 1 322 ? -27.603 23.107 -36.268 1.00 301.44 ? 1038 ASP A N 1 ATOM 2486 C CA . ASP A 1 322 ? -28.357 24.315 -35.955 1.00 304.65 ? 1038 ASP A CA 1 ATOM 2487 C C . ASP A 1 322 ? -27.455 25.383 -35.351 1.00 304.89 ? 1038 ASP A C 1 ATOM 2488 O O . ASP A 1 322 ? -26.620 25.105 -34.487 1.00 308.47 ? 1038 ASP A O 1 ATOM 2489 C CB . ASP A 1 322 ? -29.496 23.991 -34.987 1.00 310.04 ? 1038 ASP A CB 1 ATOM 2490 C CG . ASP A 1 322 ? -30.583 25.055 -34.979 1.00 315.30 ? 1038 ASP A CG 1 ATOM 2491 O OD1 . ASP A 1 322 ? -30.290 26.219 -35.319 1.00 316.24 ? 1038 ASP A OD1 1 ATOM 2492 O OD2 . ASP A 1 322 ? -31.740 24.726 -34.635 1.00 320.61 ? 1038 ASP A OD2 1 ATOM 2493 N N . VAL A 1 323 ? -27.638 26.621 -35.807 1.00 318.71 ? 1039 VAL A N 1 ATOM 2494 C CA . VAL A 1 323 ? -26.852 27.757 -35.338 1.00 319.13 ? 1039 VAL A CA 1 ATOM 2495 C C . VAL A 1 323 ? -27.529 28.487 -34.188 1.00 319.29 ? 1039 VAL A C 1 ATOM 2496 O O . VAL A 1 323 ? -27.036 29.536 -33.753 1.00 319.42 ? 1039 VAL A O 1 ATOM 2497 C CB . VAL A 1 323 ? -26.560 28.732 -36.490 1.00 320.40 ? 1039 VAL A CB 1 ATOM 2498 C CG1 . VAL A 1 323 ? -25.773 28.037 -37.565 1.00 321.31 ? 1039 VAL A CG1 1 ATOM 2499 C CG2 . VAL A 1 323 ? -27.863 29.272 -37.057 1.00 320.36 ? 1039 VAL A CG2 1 ATOM 2500 N N . GLN A 1 324 ? -28.644 27.971 -33.679 1.00 320.75 ? 1040 GLN A N 1 ATOM 2501 C CA . GLN A 1 324 ? -29.376 28.689 -32.634 1.00 320.51 ? 1040 GLN A CA 1 ATOM 2502 C C . GLN A 1 324 ? -28.646 28.590 -31.295 1.00 319.99 ? 1040 GLN A C 1 ATOM 2503 O O . GLN A 1 324 ? -28.363 27.479 -30.831 1.00 318.79 ? 1040 GLN A O 1 ATOM 2504 C CB . GLN A 1 324 ? -30.795 28.140 -32.499 1.00 321.08 ? 1040 GLN A CB 1 ATOM 2505 C CG . GLN A 1 324 ? -31.715 28.964 -31.615 1.00 321.50 ? 1040 GLN A CG 1 ATOM 2506 C CD . GLN A 1 324 ? -33.136 28.447 -31.655 1.00 322.98 ? 1040 GLN A CD 1 ATOM 2507 O OE1 . GLN A 1 324 ? -33.805 28.519 -32.688 1.00 323.45 ? 1040 GLN A OE1 1 ATOM 2508 N NE2 . GLN A 1 324 ? -33.597 27.897 -30.540 1.00 325.10 ? 1040 GLN A NE2 1 ATOM 2509 N N . PRO A 1 325 ? -28.343 29.713 -30.641 1.00 321.86 ? 1041 PRO A N 1 ATOM 2510 C CA . PRO A 1 325 ? -27.744 29.641 -29.302 1.00 323.17 ? 1041 PRO A CA 1 ATOM 2511 C C . PRO A 1 325 ? -28.754 29.166 -28.268 1.00 324.85 ? 1041 PRO A C 1 ATOM 2512 O O . PRO A 1 325 ? -29.963 29.133 -28.505 1.00 329.82 ? 1041 PRO A O 1 ATOM 2513 C CB . PRO A 1 325 ? -27.307 31.086 -29.022 1.00 321.78 ? 1041 PRO A CB 1 ATOM 2514 C CG . PRO A 1 325 ? -27.321 31.776 -30.356 1.00 322.79 ? 1041 PRO A CG 1 ATOM 2515 C CD . PRO A 1 325 ? -28.405 31.097 -31.142 1.00 322.25 ? 1041 PRO A CD 1 ATOM 2516 N N . ALA A 1 326 ? -28.232 28.782 -27.100 1.00 330.59 ? 1042 ALA A N 1 ATOM 2517 C CA . ALA A 1 326 ? -29.115 28.455 -25.984 1.00 331.54 ? 1042 ALA A CA 1 ATOM 2518 C C . ALA A 1 326 ? -29.835 29.694 -25.470 1.00 329.51 ? 1042 ALA A C 1 ATOM 2519 O O . ALA A 1 326 ? -30.963 29.598 -24.972 1.00 325.97 ? 1042 ALA A O 1 ATOM 2520 C CB . ALA A 1 326 ? -28.323 27.792 -24.857 1.00 333.19 ? 1042 ALA A CB 1 ATOM 2521 N N . ILE A 1 327 ? -29.207 30.860 -25.593 1.00 334.38 ? 1043 ILE A N 1 ATOM 2522 C CA . ILE A 1 327 ? -29.772 32.122 -25.134 1.00 335.35 ? 1043 ILE A CA 1 ATOM 2523 C C . ILE A 1 327 ? -29.512 33.180 -26.195 1.00 339.78 ? 1043 ILE A C 1 ATOM 2524 O O . ILE A 1 327 ? -28.376 33.341 -26.654 1.00 340.99 ? 1043 ILE A O 1 ATOM 2525 C CB . ILE A 1 327 ? -29.174 32.559 -23.781 1.00 332.45 ? 1043 ILE A CB 1 ATOM 2526 C CG1 . ILE A 1 327 ? -29.679 31.653 -22.655 1.00 332.01 ? 1043 ILE A CG1 1 ATOM 2527 C CG2 . ILE A 1 327 ? -29.498 34.018 -23.495 1.00 330.35 ? 1043 ILE A CG2 1 ATOM 2528 C CD1 . ILE A 1 327 ? -28.970 31.864 -21.338 1.00 332.48 ? 1043 ILE A CD1 1 ATOM 2529 N N . GLY A 1 328 ? -30.561 33.899 -26.588 1.00 334.83 ? 1044 GLY A N 1 ATOM 2530 C CA . GLY A 1 328 ? -30.420 34.972 -27.552 1.00 336.69 ? 1044 GLY A CA 1 ATOM 2531 C C . GLY A 1 328 ? -31.242 34.777 -28.808 1.00 337.23 ? 1044 GLY A C 1 ATOM 2532 O O . GLY A 1 328 ? -32.471 34.678 -28.750 1.00 339.69 ? 1044 GLY A O 1 ATOM 2533 N N . THR A 1 329 ? -30.564 34.723 -29.951 1.00 331.10 ? 1045 THR A N 1 ATOM 2534 C CA . THR A 1 329 ? -31.241 34.584 -31.232 1.00 328.86 ? 1045 THR A CA 1 ATOM 2535 C C . THR A 1 329 ? -31.981 33.252 -31.315 1.00 326.85 ? 1045 THR A C 1 ATOM 2536 O O . THR A 1 329 ? -31.544 32.237 -30.767 1.00 327.47 ? 1045 THR A O 1 ATOM 2537 C CB . THR A 1 329 ? -30.227 34.687 -32.375 1.00 330.45 ? 1045 THR A CB 1 ATOM 2538 O OG1 . THR A 1 329 ? -29.443 35.876 -32.215 1.00 333.69 ? 1045 THR A OG1 1 ATOM 2539 C CG2 . THR A 1 329 ? -30.928 34.737 -33.719 1.00 329.47 ? 1045 THR A CG2 1 ATOM 2540 N N . LYS A 1 330 ? -33.124 33.270 -31.996 1.00 334.35 ? 1046 LYS A N 1 ATOM 2541 C CA . LYS A 1 330 ? -33.840 32.063 -32.379 1.00 330.89 ? 1046 LYS A CA 1 ATOM 2542 C C . LYS A 1 330 ? -33.970 32.012 -33.893 1.00 326.61 ? 1046 LYS A C 1 ATOM 2543 O O . LYS A 1 330 ? -34.314 33.013 -34.528 1.00 328.73 ? 1046 LYS A O 1 ATOM 2544 C CB . LYS A 1 330 ? -35.232 31.998 -31.740 1.00 331.45 ? 1046 LYS A CB 1 ATOM 2545 C CG . LYS A 1 330 ? -35.241 31.464 -30.321 1.00 332.56 ? 1046 LYS A CG 1 ATOM 2546 C CD . LYS A 1 330 ? -35.041 32.573 -29.309 1.00 333.47 ? 1046 LYS A CD 1 ATOM 2547 C CE . LYS A 1 330 ? -34.852 32.004 -27.918 1.00 335.71 ? 1046 LYS A CE 1 ATOM 2548 N NZ . LYS A 1 330 ? -33.511 31.378 -27.755 1.00 338.40 ? 1046 LYS A NZ 1 ATOM 2549 N N . VAL A 1 331 ? -33.695 30.847 -34.464 1.00 325.30 ? 1047 VAL A N 1 ATOM 2550 C CA . VAL A 1 331 ? -33.785 30.645 -35.905 1.00 322.09 ? 1047 VAL A CA 1 ATOM 2551 C C . VAL A 1 331 ? -35.223 30.306 -36.267 1.00 322.08 ? 1047 VAL A C 1 ATOM 2552 O O . VAL A 1 331 ? -35.820 29.388 -35.691 1.00 320.40 ? 1047 VAL A O 1 ATOM 2553 C CB . VAL A 1 331 ? -32.825 29.535 -36.370 1.00 321.63 ? 1047 VAL A CB 1 ATOM 2554 C CG1 . VAL A 1 331 ? -32.945 29.328 -37.870 1.00 320.91 ? 1047 VAL A CG1 1 ATOM 2555 C CG2 . VAL A 1 331 ? -31.397 29.882 -35.985 1.00 321.97 ? 1047 VAL A CG2 1 ATOM 2556 N N . SER A 1 332 ? -35.783 31.050 -37.221 1.00 332.92 ? 1048 SER A N 1 ATOM 2557 C CA . SER A 1 332 ? -37.140 30.801 -37.683 1.00 330.83 ? 1048 SER A CA 1 ATOM 2558 C C . SER A 1 332 ? -37.199 29.959 -38.950 1.00 331.11 ? 1048 SER A C 1 ATOM 2559 O O . SER A 1 332 ? -38.226 29.319 -39.198 1.00 332.58 ? 1048 SER A O 1 ATOM 2560 C CB . SER A 1 332 ? -37.870 32.126 -37.935 1.00 329.17 ? 1048 SER A CB 1 ATOM 2561 O OG . SER A 1 332 ? -37.368 32.778 -39.089 1.00 329.06 ? 1048 SER A OG 1 ATOM 2562 N N . ASP A 1 333 ? -36.133 29.938 -39.748 1.00 319.85 ? 1049 ASP A N 1 ATOM 2563 C CA . ASP A 1 333 ? -36.172 29.241 -41.025 1.00 320.07 ? 1049 ASP A CA 1 ATOM 2564 C C . ASP A 1 333 ? -34.760 29.114 -41.575 1.00 318.34 ? 1049 ASP A C 1 ATOM 2565 O O . ASP A 1 333 ? -33.882 29.921 -41.257 1.00 316.57 ? 1049 ASP A O 1 ATOM 2566 C CB . ASP A 1 333 ? -37.070 29.977 -42.030 1.00 321.81 ? 1049 ASP A CB 1 ATOM 2567 C CG . ASP A 1 333 ? -37.470 29.106 -43.203 1.00 324.05 ? 1049 ASP A CG 1 ATOM 2568 O OD1 . ASP A 1 333 ? -37.324 27.870 -43.102 1.00 324.28 ? 1049 ASP A OD1 1 ATOM 2569 O OD2 . ASP A 1 333 ? -37.941 29.655 -44.221 1.00 327.05 ? 1049 ASP A OD2 1 ATOM 2570 N N . TYR A 1 334 ? -34.557 28.087 -42.396 1.00 310.58 ? 1050 TYR A N 1 ATOM 2571 C CA . TYR A 1 334 ? -33.327 27.901 -43.153 1.00 311.89 ? 1050 TYR A CA 1 ATOM 2572 C C . TYR A 1 334 ? -33.673 27.936 -44.632 1.00 313.30 ? 1050 TYR A C 1 ATOM 2573 O O . TYR A 1 334 ? -34.528 27.171 -45.091 1.00 312.50 ? 1050 TYR A O 1 ATOM 2574 C CB . TYR A 1 334 ? -32.637 26.582 -42.798 1.00 313.36 ? 1050 TYR A CB 1 ATOM 2575 C CG . TYR A 1 334 ? -31.937 26.595 -41.461 1.00 314.80 ? 1050 TYR A CG 1 ATOM 2576 C CD1 . TYR A 1 334 ? -30.681 27.171 -41.317 1.00 315.97 ? 1050 TYR A CD1 1 ATOM 2577 C CD2 . TYR A 1 334 ? -32.529 26.025 -40.342 1.00 314.58 ? 1050 TYR A CD2 1 ATOM 2578 C CE1 . TYR A 1 334 ? -30.036 27.181 -40.095 1.00 316.31 ? 1050 TYR A CE1 1 ATOM 2579 C CE2 . TYR A 1 334 ? -31.892 26.031 -39.115 1.00 314.71 ? 1050 TYR A CE2 1 ATOM 2580 C CZ . TYR A 1 334 ? -30.646 26.611 -38.998 1.00 316.34 ? 1050 TYR A CZ 1 ATOM 2581 O OH . TYR A 1 334 ? -30.007 26.620 -37.781 1.00 319.61 ? 1050 TYR A OH 1 ATOM 2582 N N . ILE A 1 335 ? -33.018 28.821 -45.370 1.00 303.99 ? 1051 ILE A N 1 ATOM 2583 C CA . ILE A 1 335 ? -33.238 28.959 -46.802 1.00 304.92 ? 1051 ILE A CA 1 ATOM 2584 C C . ILE A 1 335 ? -32.137 28.210 -47.535 1.00 305.00 ? 1051 ILE A C 1 ATOM 2585 O O . ILE A 1 335 ? -30.948 28.407 -47.254 1.00 306.27 ? 1051 ILE A O 1 ATOM 2586 C CB . ILE A 1 335 ? -33.270 30.434 -47.224 1.00 304.29 ? 1051 ILE A CB 1 ATOM 2587 C CG1 . ILE A 1 335 ? -34.451 31.158 -46.565 1.00 305.36 ? 1051 ILE A CG1 1 ATOM 2588 C CG2 . ILE A 1 335 ? -33.308 30.529 -48.733 1.00 303.55 ? 1051 ILE A CG2 1 ATOM 2589 C CD1 . ILE A 1 335 ? -35.755 30.389 -46.611 1.00 306.79 ? 1051 ILE A CD1 1 ATOM 2590 N N . LEU A 1 336 ? -32.527 27.365 -48.486 1.00 292.02 ? 1052 LEU A N 1 ATOM 2591 C CA . LEU A 1 336 ? -31.591 26.511 -49.207 1.00 293.49 ? 1052 LEU A CA 1 ATOM 2592 C C . LEU A 1 336 ? -31.864 26.627 -50.700 1.00 294.33 ? 1052 LEU A C 1 ATOM 2593 O O . LEU A 1 336 ? -32.900 26.162 -51.185 1.00 295.05 ? 1052 LEU A O 1 ATOM 2594 C CB . LEU A 1 336 ? -31.710 25.061 -48.738 1.00 294.69 ? 1052 LEU A CB 1 ATOM 2595 C CG . LEU A 1 336 ? -30.703 24.067 -49.316 1.00 296.81 ? 1052 LEU A CG 1 ATOM 2596 C CD1 . LEU A 1 336 ? -30.091 23.226 -48.208 1.00 298.35 ? 1052 LEU A CD1 1 ATOM 2597 C CD2 . LEU A 1 336 ? -31.376 23.186 -50.350 1.00 298.62 ? 1052 LEU A CD2 1 ATOM 2598 N N . GLN A 1 337 ? -30.937 27.246 -51.425 1.00 293.96 ? 1053 GLN A N 1 ATOM 2599 C CA . GLN A 1 337 ? -31.020 27.368 -52.873 1.00 294.35 ? 1053 GLN A CA 1 ATOM 2600 C C . GLN A 1 337 ? -30.092 26.357 -53.533 1.00 290.92 ? 1053 GLN A C 1 ATOM 2601 O O . GLN A 1 337 ? -29.087 25.943 -52.953 1.00 292.11 ? 1053 GLN A O 1 ATOM 2602 C CB . GLN A 1 337 ? -30.657 28.784 -53.326 1.00 298.47 ? 1053 GLN A CB 1 ATOM 2603 C CG . GLN A 1 337 ? -31.276 29.890 -52.483 1.00 303.04 ? 1053 GLN A CG 1 ATOM 2604 C CD . GLN A 1 337 ? -31.195 31.246 -53.156 1.00 306.07 ? 1053 GLN A CD 1 ATOM 2605 O OE1 . GLN A 1 337 ? -31.818 31.473 -54.193 1.00 307.77 ? 1053 GLN A OE1 1 ATOM 2606 N NE2 . GLN A 1 337 ? -30.420 32.153 -52.573 1.00 311.35 ? 1053 GLN A NE2 1 ATOM 2607 N N . HIS A 1 338 ? -30.436 25.960 -54.755 1.00 299.67 ? 1054 HIS A N 1 ATOM 2608 C CA . HIS A 1 338 ? -29.624 24.996 -55.485 1.00 301.57 ? 1054 HIS A CA 1 ATOM 2609 C C . HIS A 1 338 ? -29.793 25.209 -56.981 1.00 300.61 ? 1054 HIS A C 1 ATOM 2610 O O . HIS A 1 338 ? -30.901 25.457 -57.460 1.00 301.68 ? 1054 HIS A O 1 ATOM 2611 C CB . HIS A 1 338 ? -29.987 23.557 -55.104 1.00 304.33 ? 1054 HIS A CB 1 ATOM 2612 C CG . HIS A 1 338 ? -31.261 23.062 -55.715 1.00 306.75 ? 1054 HIS A CG 1 ATOM 2613 N ND1 . HIS A 1 338 ? -31.286 22.282 -56.851 1.00 308.26 ? 1054 HIS A ND1 1 ATOM 2614 C CD2 . HIS A 1 338 ? -32.553 23.236 -55.349 1.00 307.92 ? 1054 HIS A CD2 1 ATOM 2615 C CE1 . HIS A 1 338 ? -32.538 21.995 -57.158 1.00 312.16 ? 1054 HIS A CE1 1 ATOM 2616 N NE2 . HIS A 1 338 ? -33.327 22.562 -56.263 1.00 312.10 ? 1054 HIS A NE2 1 ATOM 2617 N N . LYS A 1 339 ? -28.685 25.115 -57.710 1.00 322.89 ? 1055 LYS A N 1 ATOM 2618 C CA . LYS A 1 339 ? -28.708 25.263 -59.156 1.00 324.04 ? 1055 LYS A CA 1 ATOM 2619 C C . LYS A 1 339 ? -27.640 24.366 -59.764 1.00 325.22 ? 1055 LYS A C 1 ATOM 2620 O O . LYS A 1 339 ? -26.660 23.999 -59.110 1.00 328.20 ? 1055 LYS A O 1 ATOM 2621 C CB . LYS A 1 339 ? -28.483 26.720 -59.584 1.00 325.64 ? 1055 LYS A CB 1 ATOM 2622 C CG . LYS A 1 339 ? -27.088 27.245 -59.286 1.00 328.99 ? 1055 LYS A CG 1 ATOM 2623 C CD . LYS A 1 339 ? -26.820 28.559 -60.005 1.00 332.23 ? 1055 LYS A CD 1 ATOM 2624 C CE . LYS A 1 339 ? -25.407 29.058 -59.735 1.00 337.74 ? 1055 LYS A CE 1 ATOM 2625 N NZ . LYS A 1 339 ? -24.970 30.066 -60.744 1.00 341.03 ? 1055 LYS A NZ 1 ATOM 2626 N N . LYS A 1 340 ? -27.851 24.007 -61.027 1.00 317.10 ? 1056 LYS A N 1 ATOM 2627 C CA . LYS A 1 340 ? -26.876 23.254 -61.805 1.00 319.07 ? 1056 LYS A CA 1 ATOM 2628 C C . LYS A 1 340 ? -26.112 24.231 -62.691 1.00 325.39 ? 1056 LYS A C 1 ATOM 2629 O O . LYS A 1 340 ? -26.719 24.956 -63.485 1.00 331.65 ? 1056 LYS A O 1 ATOM 2630 C CB . LYS A 1 340 ? -27.564 22.180 -62.647 1.00 315.38 ? 1056 LYS A CB 1 ATOM 2631 C CG . LYS A 1 340 ? -26.619 21.327 -63.482 1.00 315.41 ? 1056 LYS A CG 1 ATOM 2632 C CD . LYS A 1 340 ? -27.397 20.316 -64.310 1.00 319.51 ? 1056 LYS A CD 1 ATOM 2633 C CE . LYS A 1 340 ? -26.497 19.556 -65.266 1.00 325.47 ? 1056 LYS A CE 1 ATOM 2634 N NZ . LYS A 1 340 ? -27.278 18.642 -66.143 1.00 328.34 ? 1056 LYS A NZ 1 ATOM 2635 N N . VAL A 1 341 ? -24.792 24.256 -62.556 1.00 328.73 ? 1057 VAL A N 1 ATOM 2636 C CA . VAL A 1 341 ? -23.967 25.203 -63.281 1.00 332.14 ? 1057 VAL A CA 1 ATOM 2637 C C . VAL A 1 341 ? -23.407 24.534 -64.531 1.00 338.26 ? 1057 VAL A C 1 ATOM 2638 O O . VAL A 1 341 ? -23.440 23.315 -64.678 1.00 333.40 ? 1057 VAL A O 1 ATOM 2639 C CB . VAL A 1 341 ? -22.837 25.774 -62.403 1.00 334.02 ? 1057 VAL A CB 1 ATOM 2640 C CG1 . VAL A 1 341 ? -23.358 26.134 -61.023 1.00 334.91 ? 1057 VAL A CG1 1 ATOM 2641 C CG2 . VAL A 1 341 ? -21.705 24.777 -62.306 1.00 334.51 ? 1057 VAL A CG2 1 ATOM 2642 N N . ASP A 1 342 ? -22.871 25.351 -65.444 1.00 341.52 ? 1058 ASP A N 1 ATOM 2643 C CA . ASP A 1 342 ? -22.201 24.872 -66.645 1.00 348.66 ? 1058 ASP A CA 1 ATOM 2644 C C . ASP A 1 342 ? -21.480 26.017 -67.361 1.00 351.41 ? 1058 ASP A C 1 ATOM 2645 O O . ASP A 1 342 ? -20.302 25.906 -67.702 1.00 361.02 ? 1058 ASP A O 1 ATOM 2646 C CB . ASP A 1 342 ? -23.191 24.199 -67.606 1.00 352.52 ? 1058 ASP A CB 1 ATOM 2647 C CG . ASP A 1 342 ? -24.417 25.051 -67.878 1.00 357.76 ? 1058 ASP A CG 1 ATOM 2648 O OD1 . ASP A 1 342 ? -24.782 25.869 -67.005 1.00 366.98 ? 1058 ASP A OD1 1 ATOM 2649 O OD2 . ASP A 1 342 ? -25.020 24.897 -68.960 1.00 359.20 ? 1058 ASP A OD2 1 ATOM 2650 N N . THR A 1 347 ? -22.567 30.981 -66.652 1.00 391.04 ? 1063 THR A N 1 ATOM 2651 C CA . THR A 1 347 ? -23.533 31.122 -65.571 1.00 390.18 ? 1063 THR A CA 1 ATOM 2652 C C . THR A 1 347 ? -22.964 32.017 -64.479 1.00 390.57 ? 1063 THR A C 1 ATOM 2653 O O . THR A 1 347 ? -22.539 33.141 -64.754 1.00 382.27 ? 1063 THR A O 1 ATOM 2654 C CB . THR A 1 347 ? -23.912 29.758 -64.975 1.00 388.47 ? 1063 THR A CB 1 ATOM 2655 O OG1 . THR A 1 347 ? -22.901 29.342 -64.049 1.00 391.21 ? 1063 THR A OG1 1 ATOM 2656 C CG2 . THR A 1 347 ? -24.017 28.726 -66.076 1.00 385.76 ? 1063 THR A CG2 1 ATOM 2657 N N . ASP A 1 348 ? -22.961 31.497 -63.247 1.00 388.62 ? 1064 ASP A N 1 ATOM 2658 C CA . ASP A 1 348 ? -22.456 32.173 -62.053 1.00 390.09 ? 1064 ASP A CA 1 ATOM 2659 C C . ASP A 1 348 ? -23.298 33.397 -61.707 1.00 383.70 ? 1064 ASP A C 1 ATOM 2660 O O . ASP A 1 348 ? -23.919 34.002 -62.587 1.00 375.81 ? 1064 ASP A O 1 ATOM 2661 C CB . ASP A 1 348 ? -20.985 32.570 -62.224 1.00 392.81 ? 1064 ASP A CB 1 ATOM 2662 C CG . ASP A 1 348 ? -20.199 31.566 -63.046 1.00 395.07 ? 1064 ASP A CG 1 ATOM 2663 O OD1 . ASP A 1 348 ? -20.653 30.409 -63.172 1.00 395.89 ? 1064 ASP A OD1 1 ATOM 2664 O OD2 . ASP A 1 348 ? -19.129 31.939 -63.573 1.00 396.96 ? 1064 ASP A OD2 1 ATOM 2665 N N . LEU A 1 349 ? -23.330 33.762 -60.423 1.00 366.89 ? 1065 LEU A N 1 ATOM 2666 C CA . LEU A 1 349 ? -24.108 34.909 -59.948 1.00 366.53 ? 1065 LEU A CA 1 ATOM 2667 C C . LEU A 1 349 ? -25.563 34.822 -60.404 1.00 368.05 ? 1065 LEU A C 1 ATOM 2668 O O . LEU A 1 349 ? -26.183 35.821 -60.775 1.00 365.39 ? 1065 LEU A O 1 ATOM 2669 C CB . LEU A 1 349 ? -23.477 36.229 -60.398 1.00 365.61 ? 1065 LEU A CB 1 ATOM 2670 C CG . LEU A 1 349 ? -22.403 36.844 -59.498 1.00 367.06 ? 1065 LEU A CG 1 ATOM 2671 C CD1 . LEU A 1 349 ? -22.915 36.955 -58.070 1.00 363.95 ? 1065 LEU A CD1 1 ATOM 2672 C CD2 . LEU A 1 349 ? -21.102 36.054 -59.551 1.00 366.78 ? 1065 LEU A CD2 1 ATOM 2673 N N . TYR A 1 350 ? -26.113 33.610 -60.378 1.00 364.77 ? 1066 TYR A N 1 ATOM 2674 C CA . TYR A 1 350 ? -27.465 33.349 -60.847 1.00 357.16 ? 1066 TYR A CA 1 ATOM 2675 C C . TYR A 1 350 ? -28.260 32.650 -59.754 1.00 352.06 ? 1066 TYR A C 1 ATOM 2676 O O . TYR A 1 350 ? -27.758 31.733 -59.098 1.00 351.95 ? 1066 TYR A O 1 ATOM 2677 C CB . TYR A 1 350 ? -27.451 32.496 -62.125 1.00 357.56 ? 1066 TYR A CB 1 ATOM 2678 C CG . TYR A 1 350 ? -28.806 31.958 -62.531 1.00 359.99 ? 1066 TYR A CG 1 ATOM 2679 C CD1 . TYR A 1 350 ? -29.735 32.769 -63.170 1.00 365.85 ? 1066 TYR A CD1 1 ATOM 2680 C CD2 . TYR A 1 350 ? -29.151 30.635 -62.284 1.00 358.93 ? 1066 TYR A CD2 1 ATOM 2681 C CE1 . TYR A 1 350 ? -30.974 32.279 -63.544 1.00 368.45 ? 1066 TYR A CE1 1 ATOM 2682 C CE2 . TYR A 1 350 ? -30.386 30.137 -62.655 1.00 362.71 ? 1066 TYR A CE2 1 ATOM 2683 C CZ . TYR A 1 350 ? -31.292 30.962 -63.284 1.00 368.04 ? 1066 TYR A CZ 1 ATOM 2684 O OH . TYR A 1 350 ? -32.521 30.465 -63.653 1.00 371.25 ? 1066 TYR A OH 1 ATOM 2685 N N . THR A 1 351 ? -29.500 33.091 -59.563 1.00 350.65 ? 1067 THR A N 1 ATOM 2686 C CA . THR A 1 351 ? -30.369 32.534 -58.536 1.00 346.26 ? 1067 THR A CA 1 ATOM 2687 C C . THR A 1 351 ? -31.127 31.326 -59.071 1.00 343.81 ? 1067 THR A C 1 ATOM 2688 O O . THR A 1 351 ? -31.676 31.359 -60.176 1.00 350.33 ? 1067 THR A O 1 ATOM 2689 C CB . THR A 1 351 ? -31.360 33.586 -58.040 1.00 344.62 ? 1067 THR A CB 1 ATOM 2690 O OG1 . THR A 1 351 ? -31.979 34.225 -59.166 1.00 344.74 ? 1067 THR A OG1 1 ATOM 2691 C CG2 . THR A 1 351 ? -30.651 34.630 -57.195 1.00 342.92 ? 1067 THR A CG2 1 ATOM 2692 N N . GLY A 1 352 ? -31.164 30.262 -58.272 1.00 343.72 ? 1068 GLY A N 1 ATOM 2693 C CA . GLY A 1 352 ? -31.847 29.045 -58.663 1.00 339.10 ? 1068 GLY A CA 1 ATOM 2694 C C . GLY A 1 352 ? -33.045 28.723 -57.794 1.00 334.26 ? 1068 GLY A C 1 ATOM 2695 O O . GLY A 1 352 ? -33.599 29.614 -57.142 1.00 337.03 ? 1068 GLY A O 1 ATOM 2696 N N . GLU A 1 353 ? -33.449 27.452 -57.782 1.00 330.04 ? 1069 GLU A N 1 ATOM 2697 C CA . GLU A 1 353 ? -34.595 27.016 -56.992 1.00 326.00 ? 1069 GLU A CA 1 ATOM 2698 C C . GLU A 1 353 ? -34.439 27.419 -55.531 1.00 319.93 ? 1069 GLU A C 1 ATOM 2699 O O . GLU A 1 353 ? -33.408 27.160 -54.907 1.00 322.27 ? 1069 GLU A O 1 ATOM 2700 C CB . GLU A 1 353 ? -34.761 25.499 -57.105 1.00 331.25 ? 1069 GLU A CB 1 ATOM 2701 C CG . GLU A 1 353 ? -35.369 25.028 -58.419 1.00 337.55 ? 1069 GLU A CG 1 ATOM 2702 C CD . GLU A 1 353 ? -35.155 23.546 -58.667 1.00 343.99 ? 1069 GLU A CD 1 ATOM 2703 O OE1 . GLU A 1 353 ? -34.326 23.203 -59.536 1.00 345.81 ? 1069 GLU A OE1 1 ATOM 2704 O OE2 . GLU A 1 353 ? -35.809 22.724 -57.990 1.00 346.45 ? 1069 GLU A OE2 1 ATOM 2705 N N . PHE A 1 354 ? -35.476 28.057 -54.996 1.00 336.20 ? 1070 PHE A N 1 ATOM 2706 C CA . PHE A 1 354 ? -35.505 28.560 -53.629 1.00 328.42 ? 1070 PHE A CA 1 ATOM 2707 C C . PHE A 1 354 ? -36.368 27.632 -52.787 1.00 322.88 ? 1070 PHE A C 1 ATOM 2708 O O . PHE A 1 354 ? -37.525 27.375 -53.132 1.00 323.54 ? 1070 PHE A O 1 ATOM 2709 C CB . PHE A 1 354 ? -36.054 29.992 -53.614 1.00 327.72 ? 1070 PHE A CB 1 ATOM 2710 C CG . PHE A 1 354 ? -36.211 30.598 -52.242 1.00 328.38 ? 1070 PHE A CG 1 ATOM 2711 C CD1 . PHE A 1 354 ? -37.253 30.221 -51.406 1.00 329.83 ? 1070 PHE A CD1 1 ATOM 2712 C CD2 . PHE A 1 354 ? -35.352 31.599 -51.818 1.00 332.57 ? 1070 PHE A CD2 1 ATOM 2713 C CE1 . PHE A 1 354 ? -37.406 30.795 -50.161 1.00 332.22 ? 1070 PHE A CE1 1 ATOM 2714 C CE2 . PHE A 1 354 ? -35.506 32.184 -50.577 1.00 335.76 ? 1070 PHE A CE2 1 ATOM 2715 C CZ . PHE A 1 354 ? -36.530 31.779 -49.746 1.00 334.35 ? 1070 PHE A CZ 1 ATOM 2716 N N . LEU A 1 355 ? -35.813 27.143 -51.680 1.00 322.60 ? 1071 LEU A N 1 ATOM 2717 C CA . LEU A 1 355 ? -36.526 26.240 -50.784 1.00 318.18 ? 1071 LEU A CA 1 ATOM 2718 C C . LEU A 1 355 ? -36.468 26.781 -49.365 1.00 316.77 ? 1071 LEU A C 1 ATOM 2719 O O . LEU A 1 355 ? -35.385 26.881 -48.779 1.00 316.60 ? 1071 LEU A O 1 ATOM 2720 C CB . LEU A 1 355 ? -35.936 24.828 -50.832 1.00 316.79 ? 1071 LEU A CB 1 ATOM 2721 C CG . LEU A 1 355 ? -36.000 24.073 -52.161 1.00 317.23 ? 1071 LEU A CG 1 ATOM 2722 C CD1 . LEU A 1 355 ? -35.416 22.677 -52.000 1.00 316.68 ? 1071 LEU A CD1 1 ATOM 2723 C CD2 . LEU A 1 355 ? -37.427 24.007 -52.679 1.00 316.55 ? 1071 LEU A CD2 1 ATOM 2724 N N . SER A 1 356 ? -37.628 27.130 -48.817 1.00 331.94 ? 1072 SER A N 1 ATOM 2725 C CA . SER A 1 356 ? -37.747 27.379 -47.389 1.00 329.59 ? 1072 SER A CA 1 ATOM 2726 C C . SER A 1 356 ? -37.864 26.049 -46.662 1.00 329.44 ? 1072 SER A C 1 ATOM 2727 O O . SER A 1 356 ? -38.676 25.200 -47.036 1.00 326.88 ? 1072 SER A O 1 ATOM 2728 C CB . SER A 1 356 ? -38.966 28.253 -47.093 1.00 330.01 ? 1072 SER A CB 1 ATOM 2729 O OG . SER A 1 356 ? -39.280 28.238 -45.711 1.00 327.79 ? 1072 SER A OG 1 ATOM 2730 N N . PHE A 1 357 ? -37.044 25.860 -45.628 1.00 315.04 ? 1073 PHE A N 1 ATOM 2731 C CA . PHE A 1 357 ? -37.108 24.616 -44.866 1.00 316.81 ? 1073 PHE A CA 1 ATOM 2732 C C . PHE A 1 357 ? -38.448 24.482 -44.155 1.00 317.90 ? 1073 PHE A C 1 ATOM 2733 O O . PHE A 1 357 ? -39.045 23.398 -44.138 1.00 317.01 ? 1073 PHE A O 1 ATOM 2734 C CB . PHE A 1 357 ? -35.956 24.547 -43.865 1.00 318.29 ? 1073 PHE A CB 1 ATOM 2735 C CG . PHE A 1 357 ? -35.770 23.187 -43.258 1.00 316.84 ? 1073 PHE A CG 1 ATOM 2736 C CD1 . PHE A 1 357 ? -34.913 22.269 -43.840 1.00 315.74 ? 1073 PHE A CD1 1 ATOM 2737 C CD2 . PHE A 1 357 ? -36.452 22.824 -42.107 1.00 315.56 ? 1073 PHE A CD2 1 ATOM 2738 C CE1 . PHE A 1 357 ? -34.737 21.017 -43.287 1.00 315.88 ? 1073 PHE A CE1 1 ATOM 2739 C CE2 . PHE A 1 357 ? -36.282 21.572 -41.550 1.00 316.28 ? 1073 PHE A CE2 1 ATOM 2740 C CZ . PHE A 1 357 ? -35.422 20.666 -42.142 1.00 316.19 ? 1073 PHE A CZ 1 ATOM 2741 N N . ALA A 1 358 ? -38.939 25.574 -43.570 1.00 322.50 ? 1074 ALA A N 1 ATOM 2742 C CA . ALA A 1 358 ? -40.197 25.522 -42.832 1.00 325.54 ? 1074 ALA A CA 1 ATOM 2743 C C . ALA A 1 358 ? -41.385 25.345 -43.769 1.00 326.69 ? 1074 ALA A C 1 ATOM 2744 O O . ALA A 1 358 ? -42.284 24.539 -43.501 1.00 327.60 ? 1074 ALA A O 1 ATOM 2745 C CB . ALA A 1 358 ? -40.363 26.787 -41.989 1.00 326.47 ? 1074 ALA A CB 1 ATOM 2746 N N . ASP A 1 359 ? -41.406 26.085 -44.875 1.00 321.08 ? 1075 ASP A N 1 ATOM 2747 C CA . ASP A 1 359 ? -42.589 26.147 -45.726 1.00 322.53 ? 1075 ASP A CA 1 ATOM 2748 C C . ASP A 1 359 ? -42.572 25.111 -46.846 1.00 323.31 ? 1075 ASP A C 1 ATOM 2749 O O . ASP A 1 359 ? -43.582 24.445 -47.091 1.00 327.24 ? 1075 ASP A O 1 ATOM 2750 C CB . ASP A 1 359 ? -42.734 27.555 -46.317 1.00 322.83 ? 1075 ASP A CB 1 ATOM 2751 C CG . ASP A 1 359 ? -42.747 28.637 -45.254 1.00 325.54 ? 1075 ASP A CG 1 ATOM 2752 O OD1 . ASP A 1 359 ? -42.978 28.311 -44.071 1.00 324.57 ? 1075 ASP A OD1 1 ATOM 2753 O OD2 . ASP A 1 359 ? -42.530 29.816 -45.603 1.00 326.70 ? 1075 ASP A OD2 1 ATOM 2754 N N . ASP A 1 360 ? -41.443 24.965 -47.536 1.00 319.70 ? 1076 ASP A N 1 ATOM 2755 C CA . ASP A 1 360 ? -41.400 24.138 -48.736 1.00 321.23 ? 1076 ASP A CA 1 ATOM 2756 C C . ASP A 1 360 ? -41.005 22.693 -48.466 1.00 318.14 ? 1076 ASP A C 1 ATOM 2757 O O . ASP A 1 360 ? -41.436 21.798 -49.200 1.00 318.87 ? 1076 ASP A O 1 ATOM 2758 C CB . ASP A 1 360 ? -40.431 24.744 -49.757 1.00 324.94 ? 1076 ASP A CB 1 ATOM 2759 C CG . ASP A 1 360 ? -40.832 26.143 -50.184 1.00 327.84 ? 1076 ASP A CG 1 ATOM 2760 O OD1 . ASP A 1 360 ? -42.035 26.370 -50.435 1.00 333.37 ? 1076 ASP A OD1 1 ATOM 2761 O OD2 . ASP A 1 360 ? -39.944 27.017 -50.264 1.00 327.36 ? 1076 ASP A OD2 1 ATOM 2762 N N . LEU A 1 361 ? -40.199 22.437 -47.441 1.00 310.38 ? 1077 LEU A N 1 ATOM 2763 C CA . LEU A 1 361 ? -39.693 21.093 -47.186 1.00 308.35 ? 1077 LEU A CA 1 ATOM 2764 C C . LEU A 1 361 ? -40.506 20.328 -46.152 1.00 312.51 ? 1077 LEU A C 1 ATOM 2765 O O . LEU A 1 361 ? -40.700 19.118 -46.299 1.00 313.97 ? 1077 LEU A O 1 ATOM 2766 C CB . LEU A 1 361 ? -38.227 21.160 -46.746 1.00 305.36 ? 1077 LEU A CB 1 ATOM 2767 C CG . LEU A 1 361 ? -37.280 21.663 -47.834 1.00 303.55 ? 1077 LEU A CG 1 ATOM 2768 C CD1 . LEU A 1 361 ? -35.835 21.650 -47.360 1.00 303.27 ? 1077 LEU A CD1 1 ATOM 2769 C CD2 . LEU A 1 361 ? -37.446 20.824 -49.087 1.00 302.58 ? 1077 LEU A CD2 1 ATOM 2770 N N . LEU A 1 362 ? -40.988 21.003 -45.111 1.00 314.27 ? 1078 LEU A N 1 ATOM 2771 C CA . LEU A 1 362 ? -41.779 20.342 -44.082 1.00 318.97 ? 1078 LEU A CA 1 ATOM 2772 C C . LEU A 1 362 ? -43.274 20.373 -44.370 1.00 327.03 ? 1078 LEU A C 1 ATOM 2773 O O . LEU A 1 362 ? -44.000 19.482 -43.917 1.00 329.22 ? 1078 LEU A O 1 ATOM 2774 C CB . LEU A 1 362 ? -41.520 20.985 -42.715 1.00 318.40 ? 1078 LEU A CB 1 ATOM 2775 C CG . LEU A 1 362 ? -40.115 20.873 -42.122 1.00 316.88 ? 1078 LEU A CG 1 ATOM 2776 C CD1 . LEU A 1 362 ? -40.045 21.572 -40.770 1.00 316.31 ? 1078 LEU A CD1 1 ATOM 2777 C CD2 . LEU A 1 362 ? -39.691 19.417 -41.995 1.00 317.05 ? 1078 LEU A CD2 1 ATOM 2778 N N . SER A 1 363 ? -43.749 21.367 -45.120 1.00 321.15 ? 1079 SER A N 1 ATOM 2779 C CA . SER A 1 363 ? -45.179 21.595 -45.272 1.00 326.52 ? 1079 SER A CA 1 ATOM 2780 C C . SER A 1 363 ? -45.729 21.276 -46.656 1.00 332.80 ? 1079 SER A C 1 ATOM 2781 O O . SER A 1 363 ? -46.884 20.862 -46.761 1.00 339.66 ? 1079 SER A O 1 ATOM 2782 C CB . SER A 1 363 ? -45.519 23.053 -44.935 1.00 324.73 ? 1079 SER A CB 1 ATOM 2783 O OG . SER A 1 363 ? -45.198 23.354 -43.585 1.00 324.29 ? 1079 SER A OG 1 ATOM 2784 N N . GLY A 1 364 ? -44.944 21.452 -47.718 1.00 315.51 ? 1080 GLY A N 1 ATOM 2785 C CA . GLY A 1 364 ? -45.480 21.277 -49.057 1.00 323.41 ? 1080 GLY A CA 1 ATOM 2786 C C . GLY A 1 364 ? -44.747 20.278 -49.931 1.00 331.05 ? 1080 GLY A C 1 ATOM 2787 O O . GLY A 1 364 ? -43.558 20.443 -50.212 1.00 342.53 ? 1080 GLY A O 1 ATOM 2788 N N . LEU A 1 365 ? -45.456 19.246 -50.382 1.00 314.66 ? 1081 LEU A N 1 ATOM 2789 C CA . LEU A 1 365 ? -44.878 18.234 -51.260 1.00 316.78 ? 1081 LEU A CA 1 ATOM 2790 C C . LEU A 1 365 ? -44.874 18.748 -52.697 1.00 316.09 ? 1081 LEU A C 1 ATOM 2791 O O . LEU A 1 365 ? -45.937 19.047 -53.253 1.00 319.83 ? 1081 LEU A O 1 ATOM 2792 C CB . LEU A 1 365 ? -45.671 16.931 -51.163 1.00 317.79 ? 1081 LEU A CB 1 ATOM 2793 C CG . LEU A 1 365 ? -45.903 16.306 -49.784 1.00 316.57 ? 1081 LEU A CG 1 ATOM 2794 C CD1 . LEU A 1 365 ? -47.034 15.291 -49.840 1.00 316.92 ? 1081 LEU A CD1 1 ATOM 2795 C CD2 . LEU A 1 365 ? -44.637 15.649 -49.279 1.00 313.63 ? 1081 LEU A CD2 1 ATOM 2796 N N . GLY A 1 366 ? -43.691 18.848 -53.303 1.00 298.71 ? 1082 GLY A N 1 ATOM 2797 C CA . GLY A 1 366 ? -42.433 18.511 -52.657 1.00 297.23 ? 1082 GLY A CA 1 ATOM 2798 C C . GLY A 1 366 ? -41.792 17.224 -53.150 1.00 294.45 ? 1082 GLY A C 1 ATOM 2799 O O . GLY A 1 366 ? -40.982 17.229 -54.079 1.00 288.79 ? 1082 GLY A O 1 ATOM 2800 N N . THR A 1 367 ? -42.162 16.119 -52.508 1.00 302.79 ? 1083 THR A N 1 ATOM 2801 C CA . THR A 1 367 ? -41.662 14.790 -52.832 1.00 298.95 ? 1083 THR A CA 1 ATOM 2802 C C . THR A 1 367 ? -42.116 14.382 -54.242 1.00 295.26 ? 1083 THR A C 1 ATOM 2803 O O . THR A 1 367 ? -43.015 14.996 -54.823 1.00 296.60 ? 1083 THR A O 1 ATOM 2804 C CB . THR A 1 367 ? -42.142 13.804 -51.761 1.00 302.00 ? 1083 THR A CB 1 ATOM 2805 O OG1 . THR A 1 367 ? -43.574 13.820 -51.695 1.00 307.08 ? 1083 THR A OG1 1 ATOM 2806 C CG2 . THR A 1 367 ? -41.563 14.181 -50.407 1.00 300.75 ? 1083 THR A CG2 1 ATOM 2807 N N . SER A 1 368 ? -41.491 13.344 -54.816 1.00 302.71 ? 1084 SER A N 1 ATOM 2808 C CA . SER A 1 368 ? -40.464 12.496 -54.197 1.00 302.72 ? 1084 SER A CA 1 ATOM 2809 C C . SER A 1 368 ? -39.054 12.847 -54.645 1.00 297.92 ? 1084 SER A C 1 ATOM 2810 O O . SER A 1 368 ? -38.215 11.965 -54.813 1.00 299.20 ? 1084 SER A O 1 ATOM 2811 C CB . SER A 1 368 ? -40.739 11.023 -54.511 1.00 304.45 ? 1084 SER A CB 1 ATOM 2812 O OG . SER A 1 368 ? -42.100 10.696 -54.296 1.00 306.28 ? 1084 SER A OG 1 ATOM 2813 N N . CYS A 1 369 ? -38.793 14.135 -54.835 1.00 312.56 ? 1085 CYS A N 1 ATOM 2814 C CA . CYS A 1 369 ? -37.482 14.577 -55.290 1.00 304.94 ? 1085 CYS A CA 1 ATOM 2815 C C . CYS A 1 369 ? -36.658 15.236 -54.198 1.00 296.81 ? 1085 CYS A C 1 ATOM 2816 O O . CYS A 1 369 ? -35.428 15.125 -54.217 1.00 299.59 ? 1085 CYS A O 1 ATOM 2817 C CB . CYS A 1 369 ? -37.635 15.532 -56.477 1.00 307.25 ? 1085 CYS A CB 1 ATOM 2818 S SG . CYS A 1 369 ? -38.138 14.674 -57.981 1.00 316.16 ? 1085 CYS A SG 1 ATOM 2819 N N . VAL A 1 370 ? -37.298 15.911 -53.249 1.00 306.29 ? 1086 VAL A N 1 ATOM 2820 C CA . VAL A 1 370 ? -36.610 16.516 -52.116 1.00 300.05 ? 1086 VAL A CA 1 ATOM 2821 C C . VAL A 1 370 ? -37.318 16.103 -50.833 1.00 298.78 ? 1086 VAL A C 1 ATOM 2822 O O . VAL A 1 370 ? -38.552 16.133 -50.754 1.00 300.59 ? 1086 VAL A O 1 ATOM 2823 C CB . VAL A 1 370 ? -36.545 18.055 -52.227 1.00 299.73 ? 1086 VAL A CB 1 ATOM 2824 C CG1 . VAL A 1 370 ? -35.618 18.610 -51.169 1.00 302.05 ? 1086 VAL A CG1 1 ATOM 2825 C CG2 . VAL A 1 370 ? -36.079 18.480 -53.611 1.00 300.08 ? 1086 VAL A CG2 1 ATOM 2826 N N . ALA A 1 371 ? -36.533 15.711 -49.830 1.00 299.69 ? 1087 ALA A N 1 ATOM 2827 C CA . ALA A 1 371 ? -37.042 15.369 -48.509 1.00 299.18 ? 1087 ALA A CA 1 ATOM 2828 C C . ALA A 1 371 ? -36.109 15.953 -47.459 1.00 296.07 ? 1087 ALA A C 1 ATOM 2829 O O . ALA A 1 371 ? -34.898 16.047 -47.673 1.00 296.65 ? 1087 ALA A O 1 ATOM 2830 C CB . ALA A 1 371 ? -37.172 13.849 -48.326 1.00 299.83 ? 1087 ALA A CB 1 ATOM 2831 N N . ALA A 1 372 ? -36.679 16.348 -46.326 1.00 307.84 ? 1088 ALA A N 1 ATOM 2832 C CA . ALA A 1 372 ? -35.939 17.008 -45.261 1.00 308.10 ? 1088 ALA A CA 1 ATOM 2833 C C . ALA A 1 372 ? -36.036 16.204 -43.970 1.00 308.46 ? 1088 ALA A C 1 ATOM 2834 O O . ALA A 1 372 ? -36.805 15.248 -43.861 1.00 309.35 ? 1088 ALA A O 1 ATOM 2835 C CB . ALA A 1 372 ? -36.455 18.435 -45.037 1.00 307.62 ? 1088 ALA A CB 1 ATOM 2836 N N . GLY A 1 373 ? -35.249 16.613 -42.977 1.00 311.10 ? 1089 GLY A N 1 ATOM 2837 C CA . GLY A 1 373 ? -35.239 15.928 -41.702 1.00 312.36 ? 1089 GLY A CA 1 ATOM 2838 C C . GLY A 1 373 ? -34.490 16.684 -40.625 1.00 314.39 ? 1089 GLY A C 1 ATOM 2839 O O . GLY A 1 373 ? -33.549 17.430 -40.917 1.00 315.17 ? 1089 GLY A O 1 ATOM 2840 N N . ARG A 1 374 ? -34.911 16.497 -39.375 1.00 306.41 ? 1090 ARG A N 1 ATOM 2841 C CA . ARG A 1 374 ? -34.274 17.093 -38.208 1.00 308.63 ? 1090 ARG A CA 1 ATOM 2842 C C . ARG A 1 374 ? -34.002 16.004 -37.180 1.00 314.54 ? 1090 ARG A C 1 ATOM 2843 O O . ARG A 1 374 ? -34.859 15.152 -36.929 1.00 314.70 ? 1090 ARG A O 1 ATOM 2844 C CB . ARG A 1 374 ? -35.149 18.189 -37.589 1.00 307.54 ? 1090 ARG A CB 1 ATOM 2845 C CG . ARG A 1 374 ? -34.460 19.003 -36.500 1.00 309.72 ? 1090 ARG A CG 1 ATOM 2846 C CD . ARG A 1 374 ? -35.381 20.088 -35.969 1.00 311.15 ? 1090 ARG A CD 1 ATOM 2847 N NE . ARG A 1 374 ? -36.519 19.527 -35.249 1.00 315.62 ? 1090 ARG A NE 1 ATOM 2848 C CZ . ARG A 1 374 ? -37.621 20.206 -34.946 1.00 316.71 ? 1090 ARG A CZ 1 ATOM 2849 N NH1 . ARG A 1 374 ? -38.605 19.614 -34.283 1.00 316.97 ? 1090 ARG A NH1 1 ATOM 2850 N NH2 . ARG A 1 374 ? -37.743 21.475 -35.313 1.00 315.97 ? 1090 ARG A NH2 1 ATOM 2851 N N . SER A 1 375 ? -32.815 16.042 -36.573 1.00 307.93 ? 1091 SER A N 1 ATOM 2852 C CA . SER A 1 375 ? -32.387 14.962 -35.695 1.00 312.41 ? 1091 SER A CA 1 ATOM 2853 C C . SER A 1 375 ? -31.514 15.513 -34.576 1.00 321.79 ? 1091 SER A C 1 ATOM 2854 O O . SER A 1 375 ? -30.925 16.590 -34.692 1.00 325.20 ? 1091 SER A O 1 ATOM 2855 C CB . SER A 1 375 ? -31.629 13.881 -36.477 1.00 313.14 ? 1091 SER A CB 1 ATOM 2856 O OG . SER A 1 375 ? -31.355 12.752 -35.665 1.00 316.77 ? 1091 SER A OG 1 ATOM 2857 N N . HIS A 1 376 ? -31.434 14.749 -33.487 1.00 311.27 ? 1092 HIS A N 1 ATOM 2858 C CA . HIS A 1 376 ? -30.597 15.115 -32.350 1.00 314.82 ? 1092 HIS A CA 1 ATOM 2859 C C . HIS A 1 376 ? -29.138 14.800 -32.655 1.00 316.98 ? 1092 HIS A C 1 ATOM 2860 O O . HIS A 1 376 ? -28.821 13.726 -33.177 1.00 314.67 ? 1092 HIS A O 1 ATOM 2861 C CB . HIS A 1 376 ? -31.057 14.380 -31.092 1.00 316.15 ? 1092 HIS A CB 1 ATOM 2862 C CG . HIS A 1 376 ? -32.367 14.868 -30.556 1.00 319.49 ? 1092 HIS A CG 1 ATOM 2863 N ND1 . HIS A 1 376 ? -33.298 14.028 -29.983 1.00 323.30 ? 1092 HIS A ND1 1 ATOM 2864 C CD2 . HIS A 1 376 ? -32.900 16.111 -30.505 1.00 321.05 ? 1092 HIS A CD2 1 ATOM 2865 C CE1 . HIS A 1 376 ? -34.349 14.734 -29.603 1.00 322.45 ? 1092 HIS A CE1 1 ATOM 2866 N NE2 . HIS A 1 376 ? -34.132 16.001 -29.907 1.00 323.55 ? 1092 HIS A NE2 1 ATOM 2867 N N . GLY A 1 377 ? -28.250 15.734 -32.321 1.00 297.78 ? 1093 GLY A N 1 ATOM 2868 C CA . GLY A 1 377 ? -26.872 15.662 -32.769 1.00 306.84 ? 1093 GLY A CA 1 ATOM 2869 C C . GLY A 1 377 ? -25.880 15.041 -31.810 1.00 314.58 ? 1093 GLY A C 1 ATOM 2870 O O . GLY A 1 377 ? -26.163 14.018 -31.179 1.00 314.80 ? 1093 GLY A O 1 ATOM 2871 N N . GLU A 1 378 ? -24.699 15.658 -31.706 1.00 310.56 ? 1094 GLU A N 1 ATOM 2872 C CA . GLU A 1 378 ? -23.625 15.107 -30.885 1.00 311.36 ? 1094 GLU A CA 1 ATOM 2873 C C . GLU A 1 378 ? -24.044 15.022 -29.423 1.00 308.05 ? 1094 GLU A C 1 ATOM 2874 O O . GLU A 1 378 ? -24.122 13.931 -28.846 1.00 305.93 ? 1094 GLU A O 1 ATOM 2875 C CB . GLU A 1 378 ? -22.359 15.954 -31.042 1.00 314.86 ? 1094 GLU A CB 1 ATOM 2876 C CG . GLU A 1 378 ? -21.947 16.202 -32.487 1.00 315.97 ? 1094 GLU A CG 1 ATOM 2877 C CD . GLU A 1 378 ? -22.380 17.565 -32.998 1.00 314.60 ? 1094 GLU A CD 1 ATOM 2878 O OE1 . GLU A 1 378 ? -21.517 18.317 -33.499 1.00 313.01 ? 1094 GLU A OE1 1 ATOM 2879 O OE2 . GLU A 1 378 ? -23.583 17.887 -32.893 1.00 310.48 ? 1094 GLU A OE2 1 ATOM 2880 N N . VAL A 1 379 ? -24.305 16.170 -28.805 1.00 309.03 ? 1095 VAL A N 1 ATOM 2881 C CA . VAL A 1 379 ? -24.839 16.222 -27.447 1.00 312.17 ? 1095 VAL A CA 1 ATOM 2882 C C . VAL A 1 379 ? -26.046 17.151 -27.453 1.00 308.17 ? 1095 VAL A C 1 ATOM 2883 O O . VAL A 1 379 ? -25.890 18.362 -27.671 1.00 304.04 ? 1095 VAL A O 1 ATOM 2884 C CB . VAL A 1 379 ? -23.781 16.691 -26.434 1.00 316.33 ? 1095 VAL A CB 1 ATOM 2885 C CG1 . VAL A 1 379 ? -24.392 16.796 -25.043 1.00 316.64 ? 1095 VAL A CG1 1 ATOM 2886 C CG2 . VAL A 1 379 ? -22.592 15.744 -26.424 1.00 316.63 ? 1095 VAL A CG2 1 ATOM 2887 N N . PRO A 1 380 ? -27.257 16.633 -27.251 1.00 310.68 ? 1096 PRO A N 1 ATOM 2888 C CA . PRO A 1 380 ? -28.435 17.508 -27.185 1.00 311.68 ? 1096 PRO A CA 1 ATOM 2889 C C . PRO A 1 380 ? -28.265 18.597 -26.134 1.00 311.91 ? 1096 PRO A C 1 ATOM 2890 O O . PRO A 1 380 ? -27.641 18.394 -25.092 1.00 310.82 ? 1096 PRO A O 1 ATOM 2891 C CB . PRO A 1 380 ? -29.569 16.541 -26.822 1.00 309.72 ? 1096 PRO A CB 1 ATOM 2892 C CG . PRO A 1 380 ? -29.121 15.232 -27.380 1.00 310.40 ? 1096 PRO A CG 1 ATOM 2893 C CD . PRO A 1 380 ? -27.625 15.208 -27.203 1.00 311.11 ? 1096 PRO A CD 1 ATOM 2894 N N . GLU A 1 381 ? -28.837 19.767 -26.417 1.00 331.18 ? 1097 GLU A N 1 ATOM 2895 C CA . GLU A 1 381 ? -29.697 19.947 -27.583 1.00 327.11 ? 1097 GLU A CA 1 ATOM 2896 C C . GLU A 1 381 ? -29.121 20.879 -28.648 1.00 315.79 ? 1097 GLU A C 1 ATOM 2897 O O . GLU A 1 381 ? -29.297 22.097 -28.590 1.00 310.01 ? 1097 GLU A O 1 ATOM 2898 C CB . GLU A 1 381 ? -31.071 20.458 -27.143 1.00 334.02 ? 1097 GLU A CB 1 ATOM 2899 C CG . GLU A 1 381 ? -32.087 20.587 -28.273 1.00 338.46 ? 1097 GLU A CG 1 ATOM 2900 C CD . GLU A 1 381 ? -32.375 19.271 -28.967 1.00 341.53 ? 1097 GLU A CD 1 ATOM 2901 O OE1 . GLU A 1 381 ? -32.564 19.281 -30.202 1.00 346.71 ? 1097 GLU A OE1 1 ATOM 2902 O OE2 . GLU A 1 381 ? -32.411 18.229 -28.280 1.00 342.79 ? 1097 GLU A OE2 1 ATOM 2903 N N . VAL A 1 382 ? -28.427 20.287 -29.617 1.00 312.68 ? 1098 VAL A N 1 ATOM 2904 C CA . VAL A 1 382 ? -28.150 20.917 -30.901 1.00 305.22 ? 1098 VAL A CA 1 ATOM 2905 C C . VAL A 1 382 ? -28.746 20.021 -31.977 1.00 298.83 ? 1098 VAL A C 1 ATOM 2906 O O . VAL A 1 382 ? -28.520 18.805 -31.976 1.00 303.13 ? 1098 VAL A O 1 ATOM 2907 C CB . VAL A 1 382 ? -26.643 21.142 -31.133 1.00 304.88 ? 1098 VAL A CB 1 ATOM 2908 C CG1 . VAL A 1 382 ? -26.145 22.305 -30.292 1.00 302.40 ? 1098 VAL A CG1 1 ATOM 2909 C CG2 . VAL A 1 382 ? -25.851 19.881 -30.822 1.00 307.08 ? 1098 VAL A CG2 1 ATOM 2910 N N . SER A 1 383 ? -29.529 20.613 -32.871 1.00 320.20 ? 1099 SER A N 1 ATOM 2911 C CA . SER A 1 383 ? -30.227 19.848 -33.891 1.00 311.34 ? 1099 SER A CA 1 ATOM 2912 C C . SER A 1 383 ? -29.359 19.686 -35.132 1.00 303.42 ? 1099 SER A C 1 ATOM 2913 O O . SER A 1 383 ? -28.499 20.518 -35.428 1.00 297.19 ? 1099 SER A O 1 ATOM 2914 C CB . SER A 1 383 ? -31.550 20.522 -34.261 1.00 311.26 ? 1099 SER A CB 1 ATOM 2915 O OG . SER A 1 383 ? -32.431 20.552 -33.151 1.00 308.41 ? 1099 SER A OG 1 ATOM 2916 N N . ILE A 1 384 ? -29.592 18.593 -35.853 1.00 300.00 ? 1100 ILE A N 1 ATOM 2917 C CA . ILE A 1 384 ? -28.893 18.297 -37.098 1.00 297.52 ? 1100 ILE A CA 1 ATOM 2918 C C . ILE A 1 384 ? -29.943 18.297 -38.200 1.00 294.87 ? 1100 ILE A C 1 ATOM 2919 O O . ILE A 1 384 ? -30.669 17.312 -38.382 1.00 294.82 ? 1100 ILE A O 1 ATOM 2920 C CB . ILE A 1 384 ? -28.139 16.964 -37.042 1.00 299.01 ? 1100 ILE A CB 1 ATOM 2921 C CG1 . ILE A 1 384 ? -27.042 17.016 -35.980 1.00 300.31 ? 1100 ILE A CG1 1 ATOM 2922 C CG2 . ILE A 1 384 ? -27.536 16.632 -38.399 1.00 299.42 ? 1100 ILE A CG2 1 ATOM 2923 C CD1 . ILE A 1 384 ? -25.978 18.057 -36.245 1.00 301.62 ? 1100 ILE A CD1 1 ATOM 2924 N N . TYR A 1 385 ? -30.037 19.402 -38.930 1.00 305.52 ? 1101 TYR A N 1 ATOM 2925 C CA . TYR A 1 385 ? -30.934 19.480 -40.070 1.00 303.95 ? 1101 TYR A CA 1 ATOM 2926 C C . TYR A 1 385 ? -30.304 18.805 -41.281 1.00 303.20 ? 1101 TYR A C 1 ATOM 2927 O O . TYR A 1 385 ? -29.080 18.769 -41.432 1.00 305.45 ? 1101 TYR A O 1 ATOM 2928 C CB . TYR A 1 385 ? -31.269 20.935 -40.394 1.00 303.21 ? 1101 TYR A CB 1 ATOM 2929 C CG . TYR A 1 385 ? -32.121 21.621 -39.353 1.00 303.54 ? 1101 TYR A CG 1 ATOM 2930 C CD1 . TYR A 1 385 ? -33.505 21.617 -39.454 1.00 303.39 ? 1101 TYR A CD1 1 ATOM 2931 C CD2 . TYR A 1 385 ? -31.545 22.276 -38.273 1.00 302.64 ? 1101 TYR A CD2 1 ATOM 2932 C CE1 . TYR A 1 385 ? -34.293 22.243 -38.511 1.00 303.81 ? 1101 TYR A CE1 1 ATOM 2933 C CE2 . TYR A 1 385 ? -32.327 22.906 -37.322 1.00 304.60 ? 1101 TYR A CE2 1 ATOM 2934 C CZ . TYR A 1 385 ? -33.700 22.885 -37.446 1.00 304.84 ? 1101 TYR A CZ 1 ATOM 2935 O OH . TYR A 1 385 ? -34.485 23.509 -36.504 1.00 304.47 ? 1101 TYR A OH 1 ATOM 2936 N N . SER A 1 386 ? -31.156 18.260 -42.145 1.00 289.49 ? 1102 SER A N 1 ATOM 2937 C CA . SER A 1 386 ? -30.678 17.553 -43.322 1.00 291.71 ? 1102 SER A CA 1 ATOM 2938 C C . SER A 1 386 ? -31.725 17.620 -44.423 1.00 293.56 ? 1102 SER A C 1 ATOM 2939 O O . SER A 1 386 ? -32.921 17.766 -44.160 1.00 294.55 ? 1102 SER A O 1 ATOM 2940 C CB . SER A 1 386 ? -30.342 16.091 -43.007 1.00 291.99 ? 1102 SER A CB 1 ATOM 2941 O OG . SER A 1 386 ? -31.510 15.359 -42.678 1.00 296.62 ? 1102 SER A OG 1 ATOM 2942 N N . VAL A 1 387 ? -31.253 17.501 -45.660 1.00 294.41 ? 1103 VAL A N 1 ATOM 2943 C CA . VAL A 1 387 ? -32.106 17.521 -46.842 1.00 291.96 ? 1103 VAL A CA 1 ATOM 2944 C C . VAL A 1 387 ? -31.462 16.629 -47.895 1.00 288.68 ? 1103 VAL A C 1 ATOM 2945 O O . VAL A 1 387 ? -30.236 16.608 -48.040 1.00 288.17 ? 1103 VAL A O 1 ATOM 2946 C CB . VAL A 1 387 ? -32.316 18.962 -47.357 1.00 294.52 ? 1103 VAL A CB 1 ATOM 2947 C CG1 . VAL A 1 387 ? -30.979 19.650 -47.591 1.00 297.01 ? 1103 VAL A CG1 1 ATOM 2948 C CG2 . VAL A 1 387 ? -33.156 18.968 -48.623 1.00 295.80 ? 1103 VAL A CG2 1 ATOM 2949 N N . ILE A 1 388 ? -32.285 15.874 -48.618 1.00 289.51 ? 1104 ILE A N 1 ATOM 2950 C CA . ILE A 1 388 ? -31.803 14.930 -49.618 1.00 290.43 ? 1104 ILE A CA 1 ATOM 2951 C C . ILE A 1 388 ? -32.453 15.255 -50.958 1.00 292.12 ? 1104 ILE A C 1 ATOM 2952 O O . ILE A 1 388 ? -33.666 15.484 -51.032 1.00 294.19 ? 1104 ILE A O 1 ATOM 2953 C CB . ILE A 1 388 ? -32.072 13.468 -49.202 1.00 290.02 ? 1104 ILE A CB 1 ATOM 2954 C CG1 . ILE A 1 388 ? -31.465 12.494 -50.212 1.00 291.12 ? 1104 ILE A CG1 1 ATOM 2955 C CG2 . ILE A 1 388 ? -33.564 13.207 -49.015 1.00 291.28 ? 1104 ILE A CG2 1 ATOM 2956 C CD1 . ILE A 1 388 ? -31.456 11.056 -49.740 1.00 290.15 ? 1104 ILE A CD1 1 ATOM 2957 N N . PHE A 1 389 ? -31.637 15.304 -52.006 1.00 296.09 ? 1105 PHE A N 1 ATOM 2958 C CA . PHE A 1 389 ? -32.102 15.472 -53.377 1.00 294.98 ? 1105 PHE A CA 1 ATOM 2959 C C . PHE A 1 389 ? -32.001 14.129 -54.086 1.00 298.32 ? 1105 PHE A C 1 ATOM 2960 O O . PHE A 1 389 ? -30.942 13.495 -54.070 1.00 298.57 ? 1105 PHE A O 1 ATOM 2961 C CB . PHE A 1 389 ? -31.274 16.526 -54.116 1.00 294.13 ? 1105 PHE A CB 1 ATOM 2962 C CG . PHE A 1 389 ? -31.406 17.910 -53.547 1.00 293.74 ? 1105 PHE A CG 1 ATOM 2963 C CD1 . PHE A 1 389 ? -30.647 18.303 -52.457 1.00 295.65 ? 1105 PHE A CD1 1 ATOM 2964 C CD2 . PHE A 1 389 ? -32.284 18.822 -54.108 1.00 295.03 ? 1105 PHE A CD2 1 ATOM 2965 C CE1 . PHE A 1 389 ? -30.766 19.575 -51.935 1.00 296.33 ? 1105 PHE A CE1 1 ATOM 2966 C CE2 . PHE A 1 389 ? -32.406 20.097 -53.591 1.00 295.84 ? 1105 PHE A CE2 1 ATOM 2967 C CZ . PHE A 1 389 ? -31.646 20.473 -52.503 1.00 296.17 ? 1105 PHE A CZ 1 ATOM 2968 N N . LYS A 1 390 ? -33.100 13.695 -54.701 1.00 300.65 ? 1106 LYS A N 1 ATOM 2969 C CA . LYS A 1 390 ? -33.172 12.359 -55.272 1.00 303.01 ? 1106 LYS A CA 1 ATOM 2970 C C . LYS A 1 390 ? -33.505 12.340 -56.758 1.00 305.31 ? 1106 LYS A C 1 ATOM 2971 O O . LYS A 1 390 ? -33.615 11.251 -57.335 1.00 306.34 ? 1106 LYS A O 1 ATOM 2972 C CB . LYS A 1 390 ? -34.198 11.516 -54.500 1.00 305.98 ? 1106 LYS A CB 1 ATOM 2973 C CG . LYS A 1 390 ? -33.972 11.507 -52.992 1.00 309.17 ? 1106 LYS A CG 1 ATOM 2974 C CD . LYS A 1 390 ? -34.898 10.530 -52.279 1.00 311.41 ? 1106 LYS A CD 1 ATOM 2975 C CE . LYS A 1 390 ? -36.358 10.908 -52.460 1.00 314.95 ? 1106 LYS A CE 1 ATOM 2976 N NZ . LYS A 1 390 ? -37.256 10.069 -51.618 1.00 317.43 ? 1106 LYS A NZ 1 ATOM 2977 N N . CYS A 1 391 ? -33.660 13.502 -57.400 1.00 313.26 ? 1107 CYS A N 1 ATOM 2978 C CA . CYS A 1 391 ? -33.978 13.566 -58.822 1.00 317.67 ? 1107 CYS A CA 1 ATOM 2979 C C . CYS A 1 391 ? -32.987 14.442 -59.583 1.00 316.13 ? 1107 CYS A C 1 ATOM 2980 O O . CYS A 1 391 ? -33.356 15.083 -60.570 1.00 322.17 ? 1107 CYS A O 1 ATOM 2981 C CB . CYS A 1 391 ? -35.397 14.084 -59.053 1.00 325.51 ? 1107 CYS A CB 1 ATOM 2982 S SG . CYS A 1 391 ? -36.720 13.232 -58.177 1.00 336.65 ? 1107 CYS A SG 1 ATOM 2983 N N . LEU A 1 392 ? -31.731 14.482 -59.147 1.00 325.99 ? 1108 LEU A N 1 ATOM 2984 C CA . LEU A 1 392 ? -30.740 15.296 -59.834 1.00 322.83 ? 1108 LEU A CA 1 ATOM 2985 C C . LEU A 1 392 ? -30.353 14.649 -61.164 1.00 324.14 ? 1108 LEU A C 1 ATOM 2986 O O . LEU A 1 392 ? -30.916 13.634 -61.586 1.00 326.00 ? 1108 LEU A O 1 ATOM 2987 C CB . LEU A 1 392 ? -29.519 15.512 -58.943 1.00 321.49 ? 1108 LEU A CB 1 ATOM 2988 C CG . LEU A 1 392 ? -29.785 16.301 -57.659 1.00 321.67 ? 1108 LEU A CG 1 ATOM 2989 C CD1 . LEU A 1 392 ? -28.500 16.521 -56.876 1.00 322.58 ? 1108 LEU A CD1 1 ATOM 2990 C CD2 . LEU A 1 392 ? -30.456 17.629 -57.978 1.00 322.73 ? 1108 LEU A CD2 1 ATOM 2991 N N . GLU A 1 393 ? -29.379 15.255 -61.843 1.00 316.46 ? 1109 GLU A N 1 ATOM 2992 C CA . GLU A 1 393 ? -28.972 14.720 -63.132 1.00 319.89 ? 1109 GLU A CA 1 ATOM 2993 C C . GLU A 1 393 ? -27.539 14.201 -63.068 1.00 318.04 ? 1109 GLU A C 1 ATOM 2994 O O . GLU A 1 393 ? -26.682 14.830 -62.437 1.00 321.04 ? 1109 GLU A O 1 ATOM 2995 C CB . GLU A 1 393 ? -29.082 15.786 -64.230 1.00 327.57 ? 1109 GLU A CB 1 ATOM 2996 C CG . GLU A 1 393 ? -29.609 15.256 -65.557 1.00 336.23 ? 1109 GLU A CG 1 ATOM 2997 C CD . GLU A 1 393 ? -29.826 16.346 -66.588 1.00 343.34 ? 1109 GLU A CD 1 ATOM 2998 O OE1 . GLU A 1 393 ? -29.289 16.221 -67.710 1.00 348.80 ? 1109 GLU A OE1 1 ATOM 2999 O OE2 . GLU A 1 393 ? -30.531 17.330 -66.278 1.00 348.93 ? 1109 GLU A OE2 1 ATOM 3000 N N . PRO A 1 394 ? -27.250 13.065 -63.701 1.00 319.74 ? 1110 PRO A N 1 ATOM 3001 C CA . PRO A 1 394 ? -25.905 12.486 -63.603 1.00 319.03 ? 1110 PRO A CA 1 ATOM 3002 C C . PRO A 1 394 ? -24.859 13.340 -64.303 1.00 318.35 ? 1110 PRO A C 1 ATOM 3003 O O . PRO A 1 394 ? -25.144 14.042 -65.275 1.00 318.23 ? 1110 PRO A O 1 ATOM 3004 C CB . PRO A 1 394 ? -26.054 11.125 -64.292 1.00 318.00 ? 1110 PRO A CB 1 ATOM 3005 C CG . PRO A 1 394 ? -27.209 11.301 -65.218 1.00 320.22 ? 1110 PRO A CG 1 ATOM 3006 C CD . PRO A 1 394 ? -28.151 12.227 -64.510 1.00 320.23 ? 1110 PRO A CD 1 ATOM 3007 N N . ASP A 1 395 ? -23.629 13.256 -63.791 1.00 316.84 ? 1111 ASP A N 1 ATOM 3008 C CA . ASP A 1 395 ? -22.476 13.967 -64.348 1.00 318.45 ? 1111 ASP A CA 1 ATOM 3009 C C . ASP A 1 395 ? -22.757 15.461 -64.474 1.00 314.67 ? 1111 ASP A C 1 ATOM 3010 O O . ASP A 1 395 ? -22.501 16.087 -65.505 1.00 322.38 ? 1111 ASP A O 1 ATOM 3011 C CB . ASP A 1 395 ? -22.063 13.369 -65.695 1.00 325.40 ? 1111 ASP A CB 1 ATOM 3012 C CG . ASP A 1 395 ? -20.710 13.874 -66.174 1.00 331.60 ? 1111 ASP A CG 1 ATOM 3013 O OD1 . ASP A 1 395 ? -19.968 14.469 -65.363 1.00 332.68 ? 1111 ASP A OD1 1 ATOM 3014 O OD2 . ASP A 1 395 ? -20.388 13.665 -67.362 1.00 335.28 ? 1111 ASP A OD2 1 ATOM 3015 N N . GLY A 1 396 ? -23.297 16.029 -63.409 1.00 323.22 ? 1112 GLY A N 1 ATOM 3016 C CA . GLY A 1 396 ? -23.620 17.449 -63.378 1.00 323.62 ? 1112 GLY A CA 1 ATOM 3017 C C . GLY A 1 396 ? -23.005 18.120 -62.170 1.00 322.72 ? 1112 GLY A C 1 ATOM 3018 O O . GLY A 1 396 ? -22.968 17.552 -61.078 1.00 326.79 ? 1112 GLY A O 1 ATOM 3019 N N . LEU A 1 397 ? -22.507 19.336 -62.382 1.00 331.54 ? 1113 LEU A N 1 ATOM 3020 C CA . LEU A 1 397 ? -21.943 20.139 -61.307 1.00 332.06 ? 1113 LEU A CA 1 ATOM 3021 C C . LEU A 1 397 ? -23.044 21.010 -60.711 1.00 331.56 ? 1113 LEU A C 1 ATOM 3022 O O . LEU A 1 397 ? -23.672 21.800 -61.424 1.00 334.73 ? 1113 LEU A O 1 ATOM 3023 C CB . LEU A 1 397 ? -20.787 20.989 -61.837 1.00 332.93 ? 1113 LEU A CB 1 ATOM 3024 C CG . LEU A 1 397 ? -20.124 21.979 -60.876 1.00 335.32 ? 1113 LEU A CG 1 ATOM 3025 C CD1 . LEU A 1 397 ? -19.690 21.318 -59.584 1.00 337.64 ? 1113 LEU A CD1 1 ATOM 3026 C CD2 . LEU A 1 397 ? -18.945 22.641 -61.565 1.00 335.25 ? 1113 LEU A CD2 1 ATOM 3027 N N . TYR A 1 398 ? -23.286 20.849 -59.413 1.00 324.41 ? 1114 TYR A N 1 ATOM 3028 C CA . TYR A 1 398 ? -24.358 21.541 -58.716 1.00 323.48 ? 1114 TYR A CA 1 ATOM 3029 C C . TYR A 1 398 ? -23.783 22.463 -57.651 1.00 322.71 ? 1114 TYR A C 1 ATOM 3030 O O . TYR A 1 398 ? -22.704 22.214 -57.110 1.00 326.89 ? 1114 TYR A O 1 ATOM 3031 C CB . TYR A 1 398 ? -25.326 20.544 -58.065 1.00 323.13 ? 1114 TYR A CB 1 ATOM 3032 C CG . TYR A 1 398 ? -26.219 19.825 -59.049 1.00 322.03 ? 1114 TYR A CG 1 ATOM 3033 C CD1 . TYR A 1 398 ? -25.780 18.690 -59.719 1.00 321.52 ? 1114 TYR A CD1 1 ATOM 3034 C CD2 . TYR A 1 398 ? -27.507 20.278 -59.301 1.00 319.99 ? 1114 TYR A CD2 1 ATOM 3035 C CE1 . TYR A 1 398 ? -26.598 18.030 -60.615 1.00 322.60 ? 1114 TYR A CE1 1 ATOM 3036 C CE2 . TYR A 1 398 ? -28.332 19.624 -60.195 1.00 320.26 ? 1114 TYR A CE2 1 ATOM 3037 C CZ . TYR A 1 398 ? -27.873 18.502 -60.849 1.00 322.44 ? 1114 TYR A CZ 1 ATOM 3038 O OH . TYR A 1 398 ? -28.693 17.849 -61.740 1.00 328.56 ? 1114 TYR A OH 1 ATOM 3039 N N . LYS A 1 399 ? -24.519 23.532 -57.357 1.00 309.31 ? 1115 LYS A N 1 ATOM 3040 C CA . LYS A 1 399 ? -24.138 24.491 -56.327 1.00 310.51 ? 1115 LYS A CA 1 ATOM 3041 C C . LYS A 1 399 ? -25.294 24.649 -55.352 1.00 311.70 ? 1115 LYS A C 1 ATOM 3042 O O . LYS A 1 399 ? -26.384 25.080 -55.742 1.00 312.46 ? 1115 LYS A O 1 ATOM 3043 C CB . LYS A 1 399 ? -23.758 25.843 -56.938 1.00 313.37 ? 1115 LYS A CB 1 ATOM 3044 C CG . LYS A 1 399 ? -23.548 26.942 -55.911 1.00 317.30 ? 1115 LYS A CG 1 ATOM 3045 C CD . LYS A 1 399 ? -22.787 28.124 -56.494 1.00 320.94 ? 1115 LYS A CD 1 ATOM 3046 C CE . LYS A 1 399 ? -22.737 29.284 -55.510 1.00 325.17 ? 1115 LYS A CE 1 ATOM 3047 N NZ . LYS A 1 399 ? -21.503 30.104 -55.670 1.00 328.61 ? 1115 LYS A NZ 1 ATOM 3048 N N . PHE A 1 400 ? -25.056 24.298 -54.092 1.00 311.79 ? 1116 PHE A N 1 ATOM 3049 C CA . PHE A 1 400 ? -26.037 24.436 -53.024 1.00 308.00 ? 1116 PHE A CA 1 ATOM 3050 C C . PHE A 1 400 ? -25.596 25.549 -52.084 1.00 308.00 ? 1116 PHE A C 1 ATOM 3051 O O . PHE A 1 400 ? -24.427 25.602 -51.689 1.00 310.57 ? 1116 PHE A O 1 ATOM 3052 C CB . PHE A 1 400 ? -26.194 23.126 -52.245 1.00 305.02 ? 1116 PHE A CB 1 ATOM 3053 C CG . PHE A 1 400 ? -26.538 21.942 -53.104 1.00 302.85 ? 1116 PHE A CG 1 ATOM 3054 C CD1 . PHE A 1 400 ? -27.858 21.582 -53.315 1.00 302.36 ? 1116 PHE A CD1 1 ATOM 3055 C CD2 . PHE A 1 400 ? -25.541 21.178 -53.687 1.00 302.87 ? 1116 PHE A CD2 1 ATOM 3056 C CE1 . PHE A 1 400 ? -28.178 20.490 -54.102 1.00 302.09 ? 1116 PHE A CE1 1 ATOM 3057 C CE2 . PHE A 1 400 ? -25.853 20.085 -54.472 1.00 303.36 ? 1116 PHE A CE2 1 ATOM 3058 C CZ . PHE A 1 400 ? -27.174 19.741 -54.680 1.00 302.95 ? 1116 PHE A CZ 1 ATOM 3059 N N . THR A 1 401 ? -26.526 26.433 -51.730 1.00 297.57 ? 1117 THR A N 1 ATOM 3060 C CA . THR A 1 401 ? -26.256 27.510 -50.788 1.00 300.35 ? 1117 THR A CA 1 ATOM 3061 C C . THR A 1 401 ? -27.295 27.493 -49.677 1.00 298.91 ? 1117 THR A C 1 ATOM 3062 O O . THR A 1 401 ? -28.450 27.114 -49.890 1.00 300.78 ? 1117 THR A O 1 ATOM 3063 C CB . THR A 1 401 ? -26.243 28.886 -51.474 1.00 304.26 ? 1117 THR A CB 1 ATOM 3064 O OG1 . THR A 1 401 ? -27.503 29.119 -52.114 1.00 312.57 ? 1117 THR A OG1 1 ATOM 3065 C CG2 . THR A 1 401 ? -25.126 28.960 -52.506 1.00 306.02 ? 1117 THR A CG2 1 ATOM 3066 N N . LEU A 1 402 ? -26.872 27.919 -48.488 1.00 311.83 ? 1118 LEU A N 1 ATOM 3067 C CA . LEU A 1 402 ? -27.690 27.831 -47.287 1.00 309.79 ? 1118 LEU A CA 1 ATOM 3068 C C . LEU A 1 402 ? -27.488 29.072 -46.432 1.00 308.91 ? 1118 LEU A C 1 ATOM 3069 O O . LEU A 1 402 ? -26.365 29.567 -46.303 1.00 307.25 ? 1118 LEU A O 1 ATOM 3070 C CB . LEU A 1 402 ? -27.331 26.576 -46.476 1.00 311.24 ? 1118 LEU A CB 1 ATOM 3071 C CG . LEU A 1 402 ? -27.990 26.375 -45.109 1.00 312.94 ? 1118 LEU A CG 1 ATOM 3072 C CD1 . LEU A 1 402 ? -29.413 25.861 -45.261 1.00 313.26 ? 1118 LEU A CD1 1 ATOM 3073 C CD2 . LEU A 1 402 ? -27.158 25.434 -44.251 1.00 314.95 ? 1118 LEU A CD2 1 ATOM 3074 N N . TYR A 1 403 ? -28.577 29.575 -45.851 1.00 317.64 ? 1119 TYR A N 1 ATOM 3075 C CA . TYR A 1 403 ? -28.473 30.631 -44.854 1.00 319.21 ? 1119 TYR A CA 1 ATOM 3076 C C . TYR A 1 403 ? -29.669 30.565 -43.916 1.00 318.86 ? 1119 TYR A C 1 ATOM 3077 O O . TYR A 1 403 ? -30.758 30.126 -44.298 1.00 323.04 ? 1119 TYR A O 1 ATOM 3078 C CB . TYR A 1 403 ? -28.353 32.026 -45.491 1.00 318.92 ? 1119 TYR A CB 1 ATOM 3079 C CG . TYR A 1 403 ? -29.554 32.521 -46.276 1.00 317.98 ? 1119 TYR A CG 1 ATOM 3080 C CD1 . TYR A 1 403 ? -29.654 32.297 -47.644 1.00 318.52 ? 1119 TYR A CD1 1 ATOM 3081 C CD2 . TYR A 1 403 ? -30.564 33.251 -45.656 1.00 317.40 ? 1119 TYR A CD2 1 ATOM 3082 C CE1 . TYR A 1 403 ? -30.735 32.764 -48.367 1.00 318.62 ? 1119 TYR A CE1 1 ATOM 3083 C CE2 . TYR A 1 403 ? -31.651 33.720 -46.373 1.00 316.98 ? 1119 TYR A CE2 1 ATOM 3084 C CZ . TYR A 1 403 ? -31.732 33.474 -47.728 1.00 317.80 ? 1119 TYR A CZ 1 ATOM 3085 O OH . TYR A 1 403 ? -32.811 33.936 -48.445 1.00 316.84 ? 1119 TYR A OH 1 ATOM 3086 N N . ALA A 1 404 ? -29.449 31.001 -42.680 1.00 316.47 ? 1120 ALA A N 1 ATOM 3087 C CA . ALA A 1 404 ? -30.467 30.982 -41.642 1.00 315.45 ? 1120 ALA A CA 1 ATOM 3088 C C . ALA A 1 404 ? -31.200 32.317 -41.577 1.00 315.13 ? 1120 ALA A C 1 ATOM 3089 O O . ALA A 1 404 ? -30.678 33.361 -41.974 1.00 314.13 ? 1120 ALA A O 1 ATOM 3090 C CB . ALA A 1 404 ? -29.844 30.663 -40.282 1.00 317.11 ? 1120 ALA A CB 1 ATOM 3091 N N . VAL A 1 405 ? -32.429 32.267 -41.064 1.00 321.80 ? 1121 VAL A N 1 ATOM 3092 C CA . VAL A 1 405 ? -33.271 33.445 -40.891 1.00 322.41 ? 1121 VAL A CA 1 ATOM 3093 C C . VAL A 1 405 ? -33.803 33.424 -39.466 1.00 323.42 ? 1121 VAL A C 1 ATOM 3094 O O . VAL A 1 405 ? -34.413 32.434 -39.045 1.00 322.98 ? 1121 VAL A O 1 ATOM 3095 C CB . VAL A 1 405 ? -34.430 33.485 -41.903 1.00 321.25 ? 1121 VAL A CB 1 ATOM 3096 C CG1 . VAL A 1 405 ? -35.233 34.766 -41.735 1.00 321.18 ? 1121 VAL A CG1 1 ATOM 3097 C CG2 . VAL A 1 405 ? -33.901 33.363 -43.325 1.00 320.56 ? 1121 VAL A CG2 1 ATOM 3098 N N . ASP A 1 406 ? -33.572 34.504 -38.724 1.00 331.99 ? 1122 ASP A N 1 ATOM 3099 C CA . ASP A 1 406 ? -33.929 34.527 -37.314 1.00 336.58 ? 1122 ASP A CA 1 ATOM 3100 C C . ASP A 1 406 ? -35.383 34.959 -37.133 1.00 338.70 ? 1122 ASP A C 1 ATOM 3101 O O . ASP A 1 406 ? -36.092 35.275 -38.091 1.00 335.01 ? 1122 ASP A O 1 ATOM 3102 C CB . ASP A 1 406 ? -32.958 35.416 -36.531 1.00 340.04 ? 1122 ASP A CB 1 ATOM 3103 C CG . ASP A 1 406 ? -33.194 36.905 -36.745 1.00 345.62 ? 1122 ASP A CG 1 ATOM 3104 O OD1 . ASP A 1 406 ? -33.843 37.294 -37.740 1.00 351.11 ? 1122 ASP A OD1 1 ATOM 3105 O OD2 . ASP A 1 406 ? -32.706 37.696 -35.911 1.00 352.96 ? 1122 ASP A OD2 1 ATOM 3106 N N . THR A 1 407 ? -35.831 34.963 -35.874 1.00 335.44 ? 1123 THR A N 1 ATOM 3107 C CA . THR A 1 407 ? -37.221 35.289 -35.569 1.00 336.71 ? 1123 THR A CA 1 ATOM 3108 C C . THR A 1 407 ? -37.592 36.694 -36.021 1.00 338.10 ? 1123 THR A C 1 ATOM 3109 O O . THR A 1 407 ? -38.721 36.921 -36.475 1.00 341.03 ? 1123 THR A O 1 ATOM 3110 C CB . THR A 1 407 ? -37.470 35.126 -34.068 1.00 338.59 ? 1123 THR A CB 1 ATOM 3111 O OG1 . THR A 1 407 ? -37.535 33.730 -33.741 1.00 340.21 ? 1123 THR A OG1 1 ATOM 3112 C CG2 . THR A 1 407 ? -38.767 35.807 -33.643 1.00 342.25 ? 1123 THR A CG2 1 ATOM 3113 N N . ARG A 1 408 ? -36.665 37.641 -35.927 1.00 344.86 ? 1124 ARG A N 1 ATOM 3114 C CA . ARG A 1 408 ? -36.940 39.022 -36.300 1.00 345.39 ? 1124 ARG A CA 1 ATOM 3115 C C . ARG A 1 408 ? -36.465 39.372 -37.703 1.00 342.69 ? 1124 ARG A C 1 ATOM 3116 O O . ARG A 1 408 ? -36.475 40.551 -38.069 1.00 343.81 ? 1124 ARG A O 1 ATOM 3117 C CB . ARG A 1 408 ? -36.315 39.987 -35.298 1.00 351.44 ? 1124 ARG A CB 1 ATOM 3118 C CG . ARG A 1 408 ? -37.033 40.026 -33.969 1.00 357.41 ? 1124 ARG A CG 1 ATOM 3119 C CD . ARG A 1 408 ? -38.321 40.826 -34.046 1.00 360.12 ? 1124 ARG A CD 1 ATOM 3120 N NE . ARG A 1 408 ? -38.097 42.251 -33.811 1.00 362.48 ? 1124 ARG A NE 1 ATOM 3121 C CZ . ARG A 1 408 ? -38.030 43.166 -34.771 1.00 364.15 ? 1124 ARG A CZ 1 ATOM 3122 N NH1 . ARG A 1 408 ? -38.174 42.807 -36.038 1.00 364.30 ? 1124 ARG A NH1 1 ATOM 3123 N NH2 . ARG A 1 408 ? -37.824 44.441 -34.466 1.00 363.55 ? 1124 ARG A NH2 1 ATOM 3124 N N . GLY A 1 409 ? -36.041 38.392 -38.494 1.00 350.79 ? 1125 GLY A N 1 ATOM 3125 C CA . GLY A 1 409 ? -35.910 38.594 -39.918 1.00 349.10 ? 1125 GLY A CA 1 ATOM 3126 C C . GLY A 1 409 ? -34.508 38.765 -40.454 1.00 349.07 ? 1125 GLY A C 1 ATOM 3127 O O . GLY A 1 409 ? -34.353 38.924 -41.670 1.00 349.14 ? 1125 GLY A O 1 ATOM 3128 N N . ARG A 1 410 ? -33.486 38.738 -39.602 1.00 341.84 ? 1126 ARG A N 1 ATOM 3129 C CA . ARG A 1 410 ? -32.117 38.830 -40.090 1.00 340.56 ? 1126 ARG A CA 1 ATOM 3130 C C . ARG A 1 410 ? -31.744 37.596 -40.903 1.00 338.72 ? 1126 ARG A C 1 ATOM 3131 O O . ARG A 1 410 ? -32.218 36.486 -40.644 1.00 334.46 ? 1126 ARG A O 1 ATOM 3132 C CB . ARG A 1 410 ? -31.142 38.986 -38.924 1.00 341.54 ? 1126 ARG A CB 1 ATOM 3133 C CG . ARG A 1 410 ? -31.207 40.315 -38.203 1.00 345.86 ? 1126 ARG A CG 1 ATOM 3134 C CD . ARG A 1 410 ? -30.118 40.376 -37.151 1.00 348.31 ? 1126 ARG A CD 1 ATOM 3135 N NE . ARG A 1 410 ? -30.181 39.221 -36.260 1.00 348.59 ? 1126 ARG A NE 1 ATOM 3136 C CZ . ARG A 1 410 ? -29.209 38.862 -35.427 1.00 345.40 ? 1126 ARG A CZ 1 ATOM 3137 N NH1 . ARG A 1 410 ? -28.088 39.566 -35.370 1.00 344.59 ? 1126 ARG A NH1 1 ATOM 3138 N NH2 . ARG A 1 410 ? -29.357 37.795 -34.653 1.00 343.94 ? 1126 ARG A NH2 1 ATOM 3139 N N . HIS A 1 411 ? -30.892 37.804 -41.905 1.00 328.99 ? 1127 HIS A N 1 ATOM 3140 C CA . HIS A 1 411 ? -30.258 36.718 -42.634 1.00 327.55 ? 1127 HIS A CA 1 ATOM 3141 C C . HIS A 1 411 ? -28.879 36.452 -42.044 1.00 326.56 ? 1127 HIS A C 1 ATOM 3142 O O . HIS A 1 411 ? -28.189 37.370 -41.594 1.00 325.01 ? 1127 HIS A O 1 ATOM 3143 C CB . HIS A 1 411 ? -30.129 37.046 -44.123 1.00 329.49 ? 1127 HIS A CB 1 ATOM 3144 C CG . HIS A 1 411 ? -31.431 37.050 -44.860 1.00 332.71 ? 1127 HIS A CG 1 ATOM 3145 N ND1 . HIS A 1 411 ? -32.629 36.742 -44.253 1.00 335.97 ? 1127 HIS A ND1 1 ATOM 3146 C CD2 . HIS A 1 411 ? -31.723 37.316 -46.155 1.00 335.03 ? 1127 HIS A CD2 1 ATOM 3147 C CE1 . HIS A 1 411 ? -33.603 36.822 -45.142 1.00 337.90 ? 1127 HIS A CE1 1 ATOM 3148 N NE2 . HIS A 1 411 ? -33.080 37.168 -46.304 1.00 339.05 ? 1127 HIS A NE2 1 ATOM 3149 N N . SER A 1 412 ? -28.491 35.183 -42.030 1.00 314.93 ? 1128 SER A N 1 ATOM 3150 C CA . SER A 1 412 ? -27.144 34.843 -41.615 1.00 316.57 ? 1128 SER A CA 1 ATOM 3151 C C . SER A 1 412 ? -26.177 35.040 -42.778 1.00 318.82 ? 1128 SER A C 1 ATOM 3152 O O . SER A 1 412 ? -26.569 35.363 -43.904 1.00 316.80 ? 1128 SER A O 1 ATOM 3153 C CB . SER A 1 412 ? -27.083 33.401 -41.115 1.00 317.27 ? 1128 SER A CB 1 ATOM 3154 O OG . SER A 1 412 ? -27.235 32.486 -42.187 1.00 315.70 ? 1128 SER A OG 1 ATOM 3155 N N . GLU A 1 413 ? -24.893 34.842 -42.497 1.00 319.11 ? 1129 GLU A N 1 ATOM 3156 C CA . GLU A 1 413 ? -23.912 34.774 -43.567 1.00 325.53 ? 1129 GLU A CA 1 ATOM 3157 C C . GLU A 1 413 ? -24.149 33.509 -44.384 1.00 322.21 ? 1129 GLU A C 1 ATOM 3158 O O . GLU A 1 413 ? -24.446 32.443 -43.836 1.00 323.96 ? 1129 GLU A O 1 ATOM 3159 C CB . GLU A 1 413 ? -22.496 34.785 -42.998 1.00 336.29 ? 1129 GLU A CB 1 ATOM 3160 C CG . GLU A 1 413 ? -21.416 35.076 -44.028 1.00 346.86 ? 1129 GLU A CG 1 ATOM 3161 C CD . GLU A 1 413 ? -20.021 35.036 -43.436 1.00 356.86 ? 1129 GLU A CD 1 ATOM 3162 O OE1 . GLU A 1 413 ? -19.875 34.551 -42.294 1.00 364.01 ? 1129 GLU A OE1 1 ATOM 3163 O OE2 . GLU A 1 413 ? -19.071 35.490 -44.109 1.00 361.65 ? 1129 GLU A OE2 1 ATOM 3164 N N . LEU A 1 414 ? -24.032 33.632 -45.701 1.00 315.17 ? 1130 LEU A N 1 ATOM 3165 C CA . LEU A 1 414 ? -24.340 32.523 -46.589 1.00 313.77 ? 1130 LEU A CA 1 ATOM 3166 C C . LEU A 1 414 ? -23.238 31.467 -46.538 1.00 310.80 ? 1130 LEU A C 1 ATOM 3167 O O . LEU A 1 414 ? -22.085 31.747 -46.201 1.00 313.96 ? 1130 LEU A O 1 ATOM 3168 C CB . LEU A 1 414 ? -24.544 33.036 -48.018 1.00 314.39 ? 1130 LEU A CB 1 ATOM 3169 C CG . LEU A 1 414 ? -25.067 32.082 -49.093 1.00 315.66 ? 1130 LEU A CG 1 ATOM 3170 C CD1 . LEU A 1 414 ? -26.044 32.798 -50.009 1.00 316.29 ? 1130 LEU A CD1 1 ATOM 3171 C CD2 . LEU A 1 414 ? -23.915 31.516 -49.899 1.00 317.12 ? 1130 LEU A CD2 1 ATOM 3172 N N . SER A 1 415 ? -23.616 30.233 -46.866 1.00 309.95 ? 1131 SER A N 1 ATOM 3173 C CA . SER A 1 415 ? -22.695 29.108 -46.925 1.00 308.41 ? 1131 SER A CA 1 ATOM 3174 C C . SER A 1 415 ? -22.974 28.302 -48.182 1.00 308.89 ? 1131 SER A C 1 ATOM 3175 O O . SER A 1 415 ? -24.130 28.158 -48.588 1.00 311.66 ? 1131 SER A O 1 ATOM 3176 C CB . SER A 1 415 ? -22.823 28.218 -45.689 1.00 309.18 ? 1131 SER A CB 1 ATOM 3177 O OG . SER A 1 415 ? -22.271 26.934 -45.918 1.00 314.62 ? 1131 SER A OG 1 ATOM 3178 N N . THR A 1 416 ? -21.915 27.764 -48.783 1.00 316.85 ? 1132 THR A N 1 ATOM 3179 C CA . THR A 1 416 ? -21.989 27.195 -50.119 1.00 314.13 ? 1132 THR A CA 1 ATOM 3180 C C . THR A 1 416 ? -21.356 25.811 -50.156 1.00 311.33 ? 1132 THR A C 1 ATOM 3181 O O . THR A 1 416 ? -20.402 25.522 -49.430 1.00 317.12 ? 1132 THR A O 1 ATOM 3182 C CB . THR A 1 416 ? -21.286 28.107 -51.140 1.00 316.02 ? 1132 THR A CB 1 ATOM 3183 O OG1 . THR A 1 416 ? -21.745 29.455 -50.974 1.00 315.80 ? 1132 THR A OG1 1 ATOM 3184 C CG2 . THR A 1 416 ? -21.578 27.659 -52.561 1.00 318.06 ? 1132 THR A CG2 1 ATOM 3185 N N . VAL A 1 417 ? -21.913 24.957 -51.014 1.00 312.79 ? 1133 VAL A N 1 ATOM 3186 C CA . VAL A 1 417 ? -21.328 23.668 -51.365 1.00 315.00 ? 1133 VAL A CA 1 ATOM 3187 C C . VAL A 1 417 ? -21.481 23.470 -52.866 1.00 319.03 ? 1133 VAL A C 1 ATOM 3188 O O . VAL A 1 417 ? -22.591 23.575 -53.399 1.00 323.25 ? 1133 VAL A O 1 ATOM 3189 C CB . VAL A 1 417 ? -21.988 22.496 -50.610 1.00 313.88 ? 1133 VAL A CB 1 ATOM 3190 C CG1 . VAL A 1 417 ? -21.559 21.169 -51.219 1.00 314.67 ? 1133 VAL A CG1 1 ATOM 3191 C CG2 . VAL A 1 417 ? -21.633 22.537 -49.137 1.00 312.53 ? 1133 VAL A CG2 1 ATOM 3192 N N . THR A 1 418 ? -20.373 23.191 -53.548 1.00 325.88 ? 1134 THR A N 1 ATOM 3193 C CA . THR A 1 418 ? -20.390 22.789 -54.948 1.00 330.29 ? 1134 THR A CA 1 ATOM 3194 C C . THR A 1 418 ? -19.802 21.390 -55.077 1.00 327.54 ? 1134 THR A C 1 ATOM 3195 O O . THR A 1 418 ? -18.757 21.091 -54.490 1.00 329.66 ? 1134 THR A O 1 ATOM 3196 C CB . THR A 1 418 ? -19.613 23.773 -55.840 1.00 335.99 ? 1134 THR A CB 1 ATOM 3197 O OG1 . THR A 1 418 ? -18.272 23.916 -55.356 1.00 344.43 ? 1134 THR A OG1 1 ATOM 3198 C CG2 . THR A 1 418 ? -20.293 25.135 -55.859 1.00 337.30 ? 1134 THR A CG2 1 ATOM 3199 N N . LEU A 1 419 ? -20.485 20.538 -55.841 1.00 324.03 ? 1135 LEU A N 1 ATOM 3200 C CA . LEU A 1 419 ? -20.065 19.156 -56.035 1.00 325.69 ? 1135 LEU A CA 1 ATOM 3201 C C . LEU A 1 419 ? -20.669 18.644 -57.334 1.00 323.60 ? 1135 LEU A C 1 ATOM 3202 O O . LEU A 1 419 ? -21.538 19.277 -57.937 1.00 323.39 ? 1135 LEU A O 1 ATOM 3203 C CB . LEU A 1 419 ? -20.481 18.272 -54.854 1.00 329.47 ? 1135 LEU A CB 1 ATOM 3204 C CG . LEU A 1 419 ? -21.983 17.992 -54.722 1.00 331.45 ? 1135 LEU A CG 1 ATOM 3205 C CD1 . LEU A 1 419 ? -22.309 16.606 -55.259 1.00 332.24 ? 1135 LEU A CD1 1 ATOM 3206 C CD2 . LEU A 1 419 ? -22.471 18.144 -53.285 1.00 332.43 ? 1135 LEU A CD2 1 ATOM 3207 N N . ARG A 1 420 ? -20.206 17.468 -57.744 1.00 323.34 ? 1136 ARG A N 1 ATOM 3208 C CA . ARG A 1 420 ? -20.677 16.818 -58.953 1.00 326.11 ? 1136 ARG A CA 1 ATOM 3209 C C . ARG A 1 420 ? -21.260 15.452 -58.653 1.00 321.92 ? 1136 ARG A C 1 ATOM 3210 O O . ARG A 1 420 ? -20.682 14.670 -57.897 1.00 321.55 ? 1136 ARG A O 1 ATOM 3211 C CB . ARG A 1 420 ? -19.550 16.688 -59.931 1.00 334.50 ? 1136 ARG A CB 1 ATOM 3212 C CG . ARG A 1 420 ? -18.916 18.002 -60.098 1.00 343.49 ? 1136 ARG A CG 1 ATOM 3213 C CD . ARG A 1 420 ? -18.247 18.055 -61.415 1.00 351.47 ? 1136 ARG A CD 1 ATOM 3214 N NE . ARG A 1 420 ? -17.659 19.344 -61.711 1.00 357.93 ? 1136 ARG A NE 1 ATOM 3215 C CZ . ARG A 1 420 ? -16.640 19.889 -61.059 1.00 363.44 ? 1136 ARG A CZ 1 ATOM 3216 N NH1 . ARG A 1 420 ? -16.064 19.268 -60.034 1.00 367.19 ? 1136 ARG A NH1 1 ATOM 3217 N NH2 . ARG A 1 420 ? -16.192 21.069 -61.460 1.00 362.74 ? 1136 ARG A NH2 1 ATOM 3218 N N . THR A 1 421 ? -22.417 15.192 -59.247 1.00 308.46 ? 1137 THR A N 1 ATOM 3219 C CA . THR A 1 421 ? -23.005 13.870 -59.201 1.00 309.14 ? 1137 THR A CA 1 ATOM 3220 C C . THR A 1 421 ? -22.145 12.897 -60.001 1.00 308.38 ? 1137 THR A C 1 ATOM 3221 O O . THR A 1 421 ? -21.411 13.279 -60.917 1.00 308.84 ? 1137 THR A O 1 ATOM 3222 C CB . THR A 1 421 ? -24.438 13.896 -59.741 1.00 309.98 ? 1137 THR A CB 1 ATOM 3223 O OG1 . THR A 1 421 ? -24.431 14.317 -61.109 1.00 311.01 ? 1137 THR A OG1 1 ATOM 3224 C CG2 . THR A 1 421 ? -25.302 14.862 -58.924 1.00 309.29 ? 1137 THR A CG2 1 ATOM 3225 N N . ALA A 1 422 ? -22.243 11.621 -59.641 1.00 309.94 ? 1138 ALA A N 1 ATOM 3226 C CA . ALA A 1 422 ? -21.388 10.596 -60.221 1.00 310.66 ? 1138 ALA A CA 1 ATOM 3227 C C . ALA A 1 422 ? -21.666 10.441 -61.716 1.00 315.87 ? 1138 ALA A C 1 ATOM 3228 O O . ALA A 1 422 ? -22.556 11.077 -62.286 1.00 320.07 ? 1138 ALA A O 1 ATOM 3229 C CB . ALA A 1 422 ? -21.583 9.276 -59.481 1.00 308.75 ? 1138 ALA A CB 1 ATOM 3230 N N . CYS A 1 423 ? -20.875 9.588 -62.363 1.00 331.84 ? 1139 CYS A N 1 ATOM 3231 C CA . CYS A 1 423 ? -21.111 9.272 -63.760 1.00 336.17 ? 1139 CYS A CA 1 ATOM 3232 C C . CYS A 1 423 ? -22.338 8.377 -63.892 1.00 333.79 ? 1139 CYS A C 1 ATOM 3233 O O . CYS A 1 423 ? -22.714 7.684 -62.944 1.00 331.82 ? 1139 CYS A O 1 ATOM 3234 C CB . CYS A 1 423 ? -19.882 8.596 -64.360 1.00 344.04 ? 1139 CYS A CB 1 ATOM 3235 S SG . CYS A 1 423 ? -18.462 9.690 -64.334 1.00 359.69 ? 1139 CYS A SG 1 ATOM 3236 N N . PRO A 1 424 ? -22.990 8.384 -65.053 1.00 324.47 ? 1140 PRO A N 1 ATOM 3237 C CA . PRO A 1 424 ? -24.143 7.501 -65.245 1.00 322.56 ? 1140 PRO A CA 1 ATOM 3238 C C . PRO A 1 424 ? -23.713 6.044 -65.231 1.00 321.53 ? 1140 PRO A C 1 ATOM 3239 O O . PRO A 1 424 ? -22.560 5.701 -65.503 1.00 323.10 ? 1140 PRO A O 1 ATOM 3240 C CB . PRO A 1 424 ? -24.687 7.904 -66.622 1.00 324.67 ? 1140 PRO A CB 1 ATOM 3241 C CG . PRO A 1 424 ? -24.050 9.225 -66.935 1.00 325.92 ? 1140 PRO A CG 1 ATOM 3242 C CD . PRO A 1 424 ? -22.725 9.209 -66.245 1.00 324.78 ? 1140 PRO A CD 1 ATOM 3243 N N . LEU A 1 425 ? -24.664 5.177 -64.901 1.00 324.12 ? 1141 LEU A N 1 ATOM 3244 C CA . LEU A 1 425 ? -24.373 3.754 -64.869 1.00 326.92 ? 1141 LEU A CA 1 ATOM 3245 C C . LEU A 1 425 ? -24.146 3.222 -66.277 1.00 327.54 ? 1141 LEU A C 1 ATOM 3246 O O . LEU A 1 425 ? -24.744 3.690 -67.249 1.00 331.50 ? 1141 LEU A O 1 ATOM 3247 C CB . LEU A 1 425 ? -25.500 2.991 -64.183 1.00 328.75 ? 1141 LEU A CB 1 ATOM 3248 C CG . LEU A 1 425 ? -25.479 3.190 -62.671 1.00 330.29 ? 1141 LEU A CG 1 ATOM 3249 C CD1 . LEU A 1 425 ? -26.692 3.983 -62.205 1.00 329.97 ? 1141 LEU A CD1 1 ATOM 3250 C CD2 . LEU A 1 425 ? -25.383 1.843 -61.976 1.00 330.92 ? 1141 LEU A CD2 1 ATOM 3251 N N . VAL A 1 426 ? -23.256 2.235 -66.380 1.00 327.36 ? 1142 VAL A N 1 ATOM 3252 C CA . VAL A 1 426 ? -22.818 1.700 -67.664 1.00 327.84 ? 1142 VAL A CA 1 ATOM 3253 C C . VAL A 1 426 ? -22.800 0.182 -67.572 1.00 327.18 ? 1142 VAL A C 1 ATOM 3254 O O . VAL A 1 426 ? -22.027 -0.385 -66.794 1.00 330.83 ? 1142 VAL A O 1 ATOM 3255 C CB . VAL A 1 426 ? -21.432 2.227 -68.067 1.00 328.72 ? 1142 VAL A CB 1 ATOM 3256 C CG1 . VAL A 1 426 ? -20.920 1.496 -69.299 1.00 333.74 ? 1142 VAL A CG1 1 ATOM 3257 C CG2 . VAL A 1 426 ? -21.480 3.727 -68.314 1.00 328.42 ? 1142 VAL A CG2 1 ATOM 3258 N N . ASP A 1 427 ? -23.645 -0.477 -68.362 1.00 333.68 ? 1143 ASP A N 1 ATOM 3259 C CA . ASP A 1 427 ? -23.592 -1.928 -68.498 1.00 334.38 ? 1143 ASP A CA 1 ATOM 3260 C C . ASP A 1 427 ? -22.388 -2.253 -69.371 1.00 331.77 ? 1143 ASP A C 1 ATOM 3261 O O . ASP A 1 427 ? -22.429 -2.096 -70.593 1.00 333.59 ? 1143 ASP A O 1 ATOM 3262 C CB . ASP A 1 427 ? -24.885 -2.469 -69.098 1.00 338.39 ? 1143 ASP A CB 1 ATOM 3263 C CG . ASP A 1 427 ? -24.994 -3.981 -68.991 1.00 342.70 ? 1143 ASP A CG 1 ATOM 3264 O OD1 . ASP A 1 427 ? -23.995 -4.630 -68.613 1.00 345.56 ? 1143 ASP A OD1 1 ATOM 3265 O OD2 . ASP A 1 427 ? -26.078 -4.524 -69.291 1.00 348.68 ? 1143 ASP A OD2 1 ATOM 3266 N N . ASP A 1 428 ? -21.300 -2.697 -68.738 1.00 336.09 ? 1144 ASP A N 1 ATOM 3267 C CA . ASP A 1 428 ? -20.060 -2.917 -69.474 1.00 336.87 ? 1144 ASP A CA 1 ATOM 3268 C C . ASP A 1 428 ? -20.162 -4.117 -70.407 1.00 339.50 ? 1144 ASP A C 1 ATOM 3269 O O . ASP A 1 428 ? -19.537 -4.123 -71.473 1.00 338.49 ? 1144 ASP A O 1 ATOM 3270 C CB . ASP A 1 428 ? -18.896 -3.091 -68.500 1.00 336.61 ? 1144 ASP A CB 1 ATOM 3271 C CG . ASP A 1 428 ? -17.557 -2.788 -69.137 1.00 336.29 ? 1144 ASP A CG 1 ATOM 3272 O OD1 . ASP A 1 428 ? -17.529 -2.026 -70.127 1.00 337.54 ? 1144 ASP A OD1 1 ATOM 3273 O OD2 . ASP A 1 428 ? -16.532 -3.307 -68.647 1.00 333.00 ? 1144 ASP A OD2 1 ATOM 3274 N N . ASN A 1 429 ? -20.934 -5.137 -70.026 1.00 331.76 ? 1145 ASN A N 1 ATOM 3275 C CA . ASN A 1 429 ? -21.178 -6.259 -70.927 1.00 334.42 ? 1145 ASN A CA 1 ATOM 3276 C C . ASN A 1 429 ? -21.914 -5.799 -72.178 1.00 333.88 ? 1145 ASN A C 1 ATOM 3277 O O . ASN A 1 429 ? -21.543 -6.157 -73.301 1.00 338.39 ? 1145 ASN A O 1 ATOM 3278 C CB . ASN A 1 429 ? -21.977 -7.349 -70.209 1.00 340.42 ? 1145 ASN A CB 1 ATOM 3279 C CG . ASN A 1 429 ? -21.193 -8.015 -69.099 1.00 345.83 ? 1145 ASN A CG 1 ATOM 3280 O OD1 . ASN A 1 429 ? -20.032 -8.385 -69.276 1.00 350.73 ? 1145 ASN A OD1 1 ATOM 3281 N ND2 . ASN A 1 429 ? -21.826 -8.174 -67.943 1.00 350.42 ? 1145 ASN A ND2 1 ATOM 3282 N N . LYS A 1 430 ? -22.965 -4.997 -71.996 1.00 343.75 ? 1146 LYS A N 1 ATOM 3283 C CA . LYS A 1 430 ? -23.734 -4.492 -73.129 1.00 343.66 ? 1146 LYS A CA 1 ATOM 3284 C C . LYS A 1 430 ? -22.867 -3.643 -74.050 1.00 339.89 ? 1146 LYS A C 1 ATOM 3285 O O . LYS A 1 430 ? -23.026 -3.683 -75.275 1.00 340.34 ? 1146 LYS A O 1 ATOM 3286 C CB . LYS A 1 430 ? -24.931 -3.684 -72.622 1.00 348.12 ? 1146 LYS A CB 1 ATOM 3287 C CG . LYS A 1 430 ? -25.906 -3.243 -73.700 1.00 353.32 ? 1146 LYS A CG 1 ATOM 3288 C CD . LYS A 1 430 ? -26.691 -4.421 -74.250 1.00 358.31 ? 1146 LYS A CD 1 ATOM 3289 C CE . LYS A 1 430 ? -27.849 -3.955 -75.120 1.00 362.97 ? 1146 LYS A CE 1 ATOM 3290 N NZ . LYS A 1 430 ? -28.625 -5.101 -75.674 1.00 366.85 ? 1146 LYS A NZ 1 ATOM 3291 N N . ALA A 1 431 ? -21.939 -2.875 -73.479 1.00 341.99 ? 1147 ALA A N 1 ATOM 3292 C CA . ALA A 1 431 ? -21.088 -2.010 -74.291 1.00 339.95 ? 1147 ALA A CA 1 ATOM 3293 C C . ALA A 1 431 ? -20.140 -2.826 -75.161 1.00 338.95 ? 1147 ALA A C 1 ATOM 3294 O O . ALA A 1 431 ? -20.009 -2.567 -76.363 1.00 337.95 ? 1147 ALA A O 1 ATOM 3295 C CB . ALA A 1 431 ? -20.308 -1.052 -73.392 1.00 339.36 ? 1147 ALA A CB 1 ATOM 3296 N N . GLU A 1 432 ? -19.466 -3.813 -74.569 1.00 330.27 ? 1148 GLU A N 1 ATOM 3297 C CA . GLU A 1 432 ? -18.580 -4.672 -75.347 1.00 333.85 ? 1148 GLU A CA 1 ATOM 3298 C C . GLU A 1 432 ? -19.360 -5.518 -76.345 1.00 334.39 ? 1148 GLU A C 1 ATOM 3299 O O . GLU A 1 432 ? -18.822 -5.897 -77.392 1.00 332.97 ? 1148 GLU A O 1 ATOM 3300 C CB . GLU A 1 432 ? -17.760 -5.564 -74.413 1.00 337.01 ? 1148 GLU A CB 1 ATOM 3301 C CG . GLU A 1 432 ? -16.560 -6.223 -75.070 1.00 343.38 ? 1148 GLU A CG 1 ATOM 3302 C CD . GLU A 1 432 ? -15.739 -7.042 -74.093 1.00 347.65 ? 1148 GLU A CD 1 ATOM 3303 O OE1 . GLU A 1 432 ? -16.337 -7.717 -73.228 1.00 350.90 ? 1148 GLU A OE1 1 ATOM 3304 O OE2 . GLU A 1 432 ? -14.494 -7.004 -74.184 1.00 349.75 ? 1148 GLU A OE2 1 ATOM 3305 N N . GLU A 1 433 ? -20.623 -5.816 -76.039 1.00 338.75 ? 1149 GLU A N 1 ATOM 3306 C CA . GLU A 1 433 ? -21.467 -6.549 -76.975 1.00 337.56 ? 1149 GLU A CA 1 ATOM 3307 C C . GLU A 1 433 ? -21.836 -5.684 -78.176 1.00 331.69 ? 1149 GLU A C 1 ATOM 3308 O O . GLU A 1 433 ? -21.805 -6.154 -79.320 1.00 330.55 ? 1149 GLU A O 1 ATOM 3309 C CB . GLU A 1 433 ? -22.722 -7.042 -76.252 1.00 342.70 ? 1149 GLU A CB 1 ATOM 3310 C CG . GLU A 1 433 ? -23.719 -7.778 -77.125 1.00 349.45 ? 1149 GLU A CG 1 ATOM 3311 C CD . GLU A 1 433 ? -24.978 -8.151 -76.364 1.00 356.26 ? 1149 GLU A CD 1 ATOM 3312 O OE1 . GLU A 1 433 ? -24.860 -8.639 -75.220 1.00 363.42 ? 1149 GLU A OE1 1 ATOM 3313 O OE2 . GLU A 1 433 ? -26.085 -7.942 -76.903 1.00 359.68 ? 1149 GLU A OE2 1 ATOM 3314 N N . ILE A 1 434 ? -22.178 -4.417 -77.936 1.00 343.90 ? 1150 ILE A N 1 ATOM 3315 C CA . ILE A 1 434 ? -22.521 -3.510 -79.029 1.00 342.22 ? 1150 ILE A CA 1 ATOM 3316 C C . ILE A 1 434 ? -21.314 -3.283 -79.930 1.00 341.88 ? 1150 ILE A C 1 ATOM 3317 O O . ILE A 1 434 ? -21.434 -3.258 -81.161 1.00 341.56 ? 1150 ILE A O 1 ATOM 3318 C CB . ILE A 1 434 ? -23.068 -2.183 -78.469 1.00 342.56 ? 1150 ILE A CB 1 ATOM 3319 C CG1 . ILE A 1 434 ? -24.445 -2.394 -77.833 1.00 343.19 ? 1150 ILE A CG1 1 ATOM 3320 C CG2 . ILE A 1 434 ? -23.128 -1.117 -79.556 1.00 340.81 ? 1150 ILE A CG2 1 ATOM 3321 C CD1 . ILE A 1 434 ? -24.933 -1.207 -77.030 1.00 343.13 ? 1150 ILE A CD1 1 ATOM 3322 N N . ALA A 1 435 ? -20.132 -3.122 -79.331 1.00 336.63 ? 1151 ALA A N 1 ATOM 3323 C CA . ALA A 1 435 ? -18.924 -2.862 -80.109 1.00 335.19 ? 1151 ALA A CA 1 ATOM 3324 C C . ALA A 1 435 ? -18.633 -3.997 -81.082 1.00 336.75 ? 1151 ALA A C 1 ATOM 3325 O O . ALA A 1 435 ? -18.179 -3.759 -82.208 1.00 336.67 ? 1151 ALA A O 1 ATOM 3326 C CB . ALA A 1 435 ? -17.736 -2.638 -79.173 1.00 335.40 ? 1151 ALA A CB 1 ATOM 3327 N N . ASP A 1 436 ? -18.887 -5.239 -80.667 1.00 329.10 ? 1152 ASP A N 1 ATOM 3328 C CA . ASP A 1 436 ? -18.723 -6.370 -81.574 1.00 329.87 ? 1152 ASP A CA 1 ATOM 3329 C C . ASP A 1 436 ? -19.804 -6.373 -82.647 1.00 330.38 ? 1152 ASP A C 1 ATOM 3330 O O . ASP A 1 436 ? -19.527 -6.669 -83.815 1.00 327.73 ? 1152 ASP A O 1 ATOM 3331 C CB . ASP A 1 436 ? -18.743 -7.679 -80.788 1.00 332.61 ? 1152 ASP A CB 1 ATOM 3332 C CG . ASP A 1 436 ? -17.582 -7.796 -79.823 1.00 336.31 ? 1152 ASP A CG 1 ATOM 3333 O OD1 . ASP A 1 436 ? -16.808 -6.824 -79.698 1.00 339.90 ? 1152 ASP A OD1 1 ATOM 3334 O OD2 . ASP A 1 436 ? -17.449 -8.859 -79.182 1.00 340.75 ? 1152 ASP A OD2 1 ATOM 3335 N N . LYS A 1 437 ? -21.041 -6.052 -82.267 1.00 328.03 ? 1153 LYS A N 1 ATOM 3336 C CA . LYS A 1 437 ? -22.125 -5.951 -83.238 1.00 331.56 ? 1153 LYS A CA 1 ATOM 3337 C C . LYS A 1 437 ? -21.813 -4.898 -84.294 1.00 332.20 ? 1153 LYS A C 1 ATOM 3338 O O . LYS A 1 437 ? -22.031 -5.118 -85.492 1.00 338.55 ? 1153 LYS A O 1 ATOM 3339 C CB . LYS A 1 437 ? -23.436 -5.634 -82.511 1.00 335.49 ? 1153 LYS A CB 1 ATOM 3340 C CG . LYS A 1 437 ? -24.622 -5.317 -83.407 1.00 340.15 ? 1153 LYS A CG 1 ATOM 3341 C CD . LYS A 1 437 ? -25.855 -5.020 -82.561 1.00 346.32 ? 1153 LYS A CD 1 ATOM 3342 C CE . LYS A 1 437 ? -26.966 -4.376 -83.377 1.00 350.84 ? 1153 LYS A CE 1 ATOM 3343 N NZ . LYS A 1 437 ? -27.476 -5.273 -84.449 1.00 354.97 ? 1153 LYS A NZ 1 ATOM 3344 N N . ILE A 1 438 ? -21.278 -3.751 -83.869 1.00 341.53 ? 1154 ILE A N 1 ATOM 3345 C CA . ILE A 1 438 ? -20.941 -2.686 -84.811 1.00 338.52 ? 1154 ILE A CA 1 ATOM 3346 C C . ILE A 1 438 ? -19.807 -3.120 -85.731 1.00 336.95 ? 1154 ILE A C 1 ATOM 3347 O O . ILE A 1 438 ? -19.807 -2.811 -86.929 1.00 336.74 ? 1154 ILE A O 1 ATOM 3348 C CB . ILE A 1 438 ? -20.587 -1.393 -84.050 1.00 337.78 ? 1154 ILE A CB 1 ATOM 3349 C CG1 . ILE A 1 438 ? -21.814 -0.860 -83.306 1.00 338.24 ? 1154 ILE A CG1 1 ATOM 3350 C CG2 . ILE A 1 438 ? -20.040 -0.339 -84.999 1.00 338.17 ? 1154 ILE A CG2 1 ATOM 3351 C CD1 . ILE A 1 438 ? -22.941 -0.422 -84.211 1.00 339.78 ? 1154 ILE A CD1 1 ATOM 3352 N N . TYR A 1 439 ? -18.828 -3.849 -85.193 1.00 332.91 ? 1155 TYR A N 1 ATOM 3353 C CA . TYR A 1 439 ? -17.685 -4.261 -86.002 1.00 334.41 ? 1155 TYR A CA 1 ATOM 3354 C C . TYR A 1 439 ? -18.089 -5.262 -87.074 1.00 336.50 ? 1155 TYR A C 1 ATOM 3355 O O . TYR A 1 439 ? -17.625 -5.174 -88.218 1.00 334.90 ? 1155 TYR A O 1 ATOM 3356 C CB . TYR A 1 439 ? -16.590 -4.848 -85.112 1.00 333.98 ? 1155 TYR A CB 1 ATOM 3357 C CG . TYR A 1 439 ? -15.398 -5.364 -85.884 1.00 334.34 ? 1155 TYR A CG 1 ATOM 3358 C CD1 . TYR A 1 439 ? -14.476 -4.487 -86.439 1.00 335.74 ? 1155 TYR A CD1 1 ATOM 3359 C CD2 . TYR A 1 439 ? -15.193 -6.728 -86.058 1.00 333.30 ? 1155 TYR A CD2 1 ATOM 3360 C CE1 . TYR A 1 439 ? -13.382 -4.951 -87.144 1.00 335.49 ? 1155 TYR A CE1 1 ATOM 3361 C CE2 . TYR A 1 439 ? -14.100 -7.202 -86.762 1.00 333.39 ? 1155 TYR A CE2 1 ATOM 3362 C CZ . TYR A 1 439 ? -13.198 -6.309 -87.303 1.00 333.94 ? 1155 TYR A CZ 1 ATOM 3363 O OH . TYR A 1 439 ? -12.110 -6.773 -88.004 1.00 335.05 ? 1155 TYR A OH 1 ATOM 3364 N N . ASN A 1 440 ? -18.947 -6.222 -86.727 1.00 321.92 ? 1156 ASN A N 1 ATOM 3365 C CA . ASN A 1 440 ? -19.371 -7.219 -87.701 1.00 323.81 ? 1156 ASN A CA 1 ATOM 3366 C C . ASN A 1 440 ? -20.288 -6.630 -88.763 1.00 324.41 ? 1156 ASN A C 1 ATOM 3367 O O . ASN A 1 440 ? -20.378 -7.184 -89.864 1.00 332.14 ? 1156 ASN A O 1 ATOM 3368 C CB . ASN A 1 440 ? -20.056 -8.389 -86.993 1.00 326.85 ? 1156 ASN A CB 1 ATOM 3369 C CG . ASN A 1 440 ? -19.099 -9.188 -86.129 1.00 330.17 ? 1156 ASN A CG 1 ATOM 3370 O OD1 . ASN A 1 440 ? -17.944 -9.405 -86.498 1.00 333.44 ? 1156 ASN A OD1 1 ATOM 3371 N ND2 . ASN A 1 440 ? -19.575 -9.628 -84.972 1.00 332.69 ? 1156 ASN A ND2 1 ATOM 3372 N N . LEU A 1 441 ? -20.969 -5.524 -88.461 1.00 327.59 ? 1157 LEU A N 1 ATOM 3373 C CA . LEU A 1 441 ? -21.697 -4.808 -89.502 1.00 327.19 ? 1157 LEU A CA 1 ATOM 3374 C C . LEU A 1 441 ? -20.734 -4.057 -90.413 1.00 326.53 ? 1157 LEU A C 1 ATOM 3375 O O . LEU A 1 441 ? -20.899 -4.060 -91.636 1.00 330.09 ? 1157 LEU A O 1 ATOM 3376 C CB . LEU A 1 441 ? -22.709 -3.842 -88.884 1.00 327.39 ? 1157 LEU A CB 1 ATOM 3377 C CG . LEU A 1 441 ? -23.844 -4.424 -88.040 1.00 329.19 ? 1157 LEU A CG 1 ATOM 3378 C CD1 . LEU A 1 441 ? -24.936 -3.386 -87.804 1.00 330.58 ? 1157 LEU A CD1 1 ATOM 3379 C CD2 . LEU A 1 441 ? -24.423 -5.683 -88.670 1.00 330.37 ? 1157 LEU A CD2 1 ATOM 3380 N N . TYR A 1 442 ? -19.722 -3.410 -89.831 1.00 335.27 ? 1158 TYR A N 1 ATOM 3381 C CA . TYR A 1 442 ? -18.740 -2.701 -90.641 1.00 336.84 ? 1158 TYR A CA 1 ATOM 3382 C C . TYR A 1 442 ? -17.940 -3.664 -91.502 1.00 344.92 ? 1158 TYR A C 1 ATOM 3383 O O . TYR A 1 442 ? -17.425 -3.279 -92.560 1.00 349.18 ? 1158 TYR A O 1 ATOM 3384 C CB . TYR A 1 442 ? -17.806 -1.875 -89.751 1.00 334.66 ? 1158 TYR A CB 1 ATOM 3385 C CG . TYR A 1 442 ? -18.449 -0.669 -89.088 1.00 330.97 ? 1158 TYR A CG 1 ATOM 3386 C CD1 . TYR A 1 442 ? -19.797 -0.373 -89.266 1.00 329.19 ? 1158 TYR A CD1 1 ATOM 3387 C CD2 . TYR A 1 442 ? -17.694 0.180 -88.290 1.00 328.07 ? 1158 TYR A CD2 1 ATOM 3388 C CE1 . TYR A 1 442 ? -20.374 0.736 -88.656 1.00 328.18 ? 1158 TYR A CE1 1 ATOM 3389 C CE2 . TYR A 1 442 ? -18.260 1.289 -87.682 1.00 327.56 ? 1158 TYR A CE2 1 ATOM 3390 C CZ . TYR A 1 442 ? -19.598 1.562 -87.867 1.00 327.84 ? 1158 TYR A CZ 1 ATOM 3391 O OH . TYR A 1 442 ? -20.162 2.663 -87.262 1.00 327.62 ? 1158 TYR A OH 1 ATOM 3392 N N . ASN A 1 443 ? -17.820 -4.915 -91.067 1.00 323.01 ? 1159 ASN A N 1 ATOM 3393 C CA . ASN A 1 443 ? -17.198 -5.937 -91.888 1.00 330.18 ? 1159 ASN A CA 1 ATOM 3394 C C . ASN A 1 443 ? -18.174 -6.535 -92.893 1.00 338.62 ? 1159 ASN A C 1 ATOM 3395 O O . ASN A 1 443 ? -17.742 -7.156 -93.870 1.00 344.06 ? 1159 ASN A O 1 ATOM 3396 C CB . ASN A 1 443 ? -16.606 -7.032 -90.999 1.00 331.93 ? 1159 ASN A CB 1 ATOM 3397 C CG . ASN A 1 443 ? -15.100 -7.135 -91.127 1.00 334.42 ? 1159 ASN A CG 1 ATOM 3398 O OD1 . ASN A 1 443 ? -14.531 -6.822 -92.172 1.00 337.63 ? 1159 ASN A OD1 1 ATOM 3399 N ND2 . ASN A 1 443 ? -14.446 -7.586 -90.063 1.00 338.29 ? 1159 ASN A ND2 1 ATOM 3400 N N . GLY A 1 444 ? -19.477 -6.353 -92.679 1.00 329.98 ? 1160 GLY A N 1 ATOM 3401 C CA . GLY A 1 444 ? -20.452 -6.759 -93.674 1.00 335.06 ? 1160 GLY A CA 1 ATOM 3402 C C . GLY A 1 444 ? -20.613 -5.748 -94.788 1.00 342.10 ? 1160 GLY A C 1 ATOM 3403 O O . GLY A 1 444 ? -20.963 -6.116 -95.915 1.00 339.33 ? 1160 GLY A O 1 ATOM 3404 N N . TYR A 1 445 ? -20.373 -4.469 -94.489 1.00 340.21 ? 1161 TYR A N 1 ATOM 3405 C CA . TYR A 1 445 ? -20.358 -3.389 -95.472 1.00 339.36 ? 1161 TYR A CA 1 ATOM 3406 C C . TYR A 1 445 ? -21.700 -3.154 -96.150 1.00 339.96 ? 1161 TYR A C 1 ATOM 3407 O O . TYR A 1 445 ? -22.412 -2.199 -95.822 1.00 333.70 ? 1161 TYR A O 1 ATOM 3408 C CB . TYR A 1 445 ? -19.310 -3.660 -96.559 1.00 341.87 ? 1161 TYR A CB 1 ATOM 3409 C CG . TYR A 1 445 ? -17.868 -3.508 -96.145 1.00 341.18 ? 1161 TYR A CG 1 ATOM 3410 C CD1 . TYR A 1 445 ? -17.211 -4.520 -95.460 1.00 340.26 ? 1161 TYR A CD1 1 ATOM 3411 C CD2 . TYR A 1 445 ? -17.151 -2.365 -96.476 1.00 339.72 ? 1161 TYR A CD2 1 ATOM 3412 C CE1 . TYR A 1 445 ? -15.888 -4.391 -95.094 1.00 341.65 ? 1161 TYR A CE1 1 ATOM 3413 C CE2 . TYR A 1 445 ? -15.826 -2.228 -96.118 1.00 340.49 ? 1161 TYR A CE2 1 ATOM 3414 C CZ . TYR A 1 445 ? -15.201 -3.242 -95.425 1.00 342.23 ? 1161 TYR A CZ 1 ATOM 3415 O OH . TYR A 1 445 ? -13.881 -3.111 -95.062 1.00 339.29 ? 1161 TYR A OH 1 ATOM 3416 N N . THR A 1 446 ? -22.050 -4.051 -97.074 1.00 339.12 ? 1162 THR A N 1 ATOM 3417 C CA . THR A 1 446 ? -22.928 -3.722 -98.197 1.00 341.66 ? 1162 THR A CA 1 ATOM 3418 C C . THR A 1 446 ? -24.249 -3.090 -97.770 1.00 343.81 ? 1162 THR A C 1 ATOM 3419 O O . THR A 1 446 ? -24.635 -2.030 -98.278 1.00 359.04 ? 1162 THR A O 1 ATOM 3420 C CB . THR A 1 446 ? -23.194 -4.981 -99.024 1.00 334.16 ? 1162 THR A CB 1 ATOM 3421 O OG1 . THR A 1 446 ? -21.946 -5.590 -99.382 1.00 329.99 ? 1162 THR A OG1 1 ATOM 3422 C CG2 . THR A 1 446 ? -23.968 -4.636 -100.287 1.00 329.06 ? 1162 THR A CG2 1 ATOM 3423 N N . SER A 1 447 ? -24.959 -3.731 -96.846 1.00 343.42 ? 1163 SER A N 1 ATOM 3424 C CA . SER A 1 447 ? -26.368 -3.421 -96.638 1.00 332.18 ? 1163 SER A CA 1 ATOM 3425 C C . SER A 1 447 ? -26.578 -2.011 -96.101 1.00 322.19 ? 1163 SER A C 1 ATOM 3426 O O . SER A 1 447 ? -25.839 -1.539 -95.234 1.00 318.82 ? 1163 SER A O 1 ATOM 3427 C CB . SER A 1 447 ? -26.995 -4.433 -95.681 1.00 330.76 ? 1163 SER A CB 1 ATOM 3428 O OG . SER A 1 447 ? -28.370 -4.156 -95.484 1.00 330.66 ? 1163 SER A OG 1 ATOM 3429 N N . GLY A 1 448 ? -27.603 -1.336 -96.633 1.00 329.66 ? 1164 GLY A N 1 ATOM 3430 C CA . GLY A 1 448 ? -28.074 -0.098 -96.040 1.00 329.62 ? 1164 GLY A CA 1 ATOM 3431 C C . GLY A 1 448 ? -28.905 -0.297 -94.794 1.00 334.40 ? 1164 GLY A C 1 ATOM 3432 O O . GLY A 1 448 ? -29.067 0.644 -94.011 1.00 336.83 ? 1164 GLY A O 1 ATOM 3433 N N . LYS A 1 449 ? -29.451 -1.500 -94.604 1.00 323.99 ? 1165 LYS A N 1 ATOM 3434 C CA . LYS A 1 449 ? -30.037 -1.856 -93.316 1.00 329.44 ? 1165 LYS A CA 1 ATOM 3435 C C . LYS A 1 449 ? -28.962 -1.915 -92.241 1.00 331.93 ? 1165 LYS A C 1 ATOM 3436 O O . LYS A 1 449 ? -29.147 -1.403 -91.132 1.00 337.37 ? 1165 LYS A O 1 ATOM 3437 C CB . LYS A 1 449 ? -30.760 -3.200 -93.411 1.00 332.79 ? 1165 LYS A CB 1 ATOM 3438 C CG . LYS A 1 449 ? -31.878 -3.269 -94.433 1.00 334.13 ? 1165 LYS A CG 1 ATOM 3439 C CD . LYS A 1 449 ? -32.447 -4.679 -94.479 1.00 335.71 ? 1165 LYS A CD 1 ATOM 3440 C CE . LYS A 1 449 ? -33.651 -4.780 -95.396 1.00 336.35 ? 1165 LYS A CE 1 ATOM 3441 N NZ . LYS A 1 449 ? -34.220 -6.157 -95.395 1.00 336.38 ? 1165 LYS A NZ 1 ATOM 3442 N N . GLU A 1 450 ? -27.831 -2.552 -92.555 1.00 336.42 ? 1166 GLU A N 1 ATOM 3443 C CA . GLU A 1 450 ? -26.706 -2.596 -91.627 1.00 334.66 ? 1166 GLU A CA 1 ATOM 3444 C C . GLU A 1 450 ? -26.247 -1.193 -91.260 1.00 329.10 ? 1166 GLU A C 1 ATOM 3445 O O . GLU A 1 450 ? -26.010 -0.893 -90.084 1.00 328.56 ? 1166 GLU A O 1 ATOM 3446 C CB . GLU A 1 450 ? -25.550 -3.393 -92.238 1.00 336.58 ? 1166 GLU A CB 1 ATOM 3447 C CG . GLU A 1 450 ? -25.759 -4.896 -92.280 1.00 336.83 ? 1166 GLU A CG 1 ATOM 3448 C CD . GLU A 1 450 ? -24.609 -5.616 -92.960 1.00 338.00 ? 1166 GLU A CD 1 ATOM 3449 O OE1 . GLU A 1 450 ? -24.197 -5.181 -94.056 1.00 335.66 ? 1166 GLU A OE1 1 ATOM 3450 O OE2 . GLU A 1 450 ? -24.108 -6.610 -92.394 1.00 338.55 ? 1166 GLU A OE2 1 ATOM 3451 N N . GLN A 1 451 ? -26.118 -0.317 -92.258 1.00 339.62 ? 1167 GLN A N 1 ATOM 3452 C CA . GLN A 1 451 ? -25.696 1.055 -91.995 1.00 339.47 ? 1167 GLN A CA 1 ATOM 3453 C C . GLN A 1 451 ? -26.688 1.777 -91.095 1.00 336.17 ? 1167 GLN A C 1 ATOM 3454 O O . GLN A 1 451 ? -26.292 2.464 -90.146 1.00 333.19 ? 1167 GLN A O 1 ATOM 3455 C CB . GLN A 1 451 ? -25.523 1.815 -93.311 1.00 343.92 ? 1167 GLN A CB 1 ATOM 3456 C CG . GLN A 1 451 ? -24.359 1.343 -94.163 1.00 346.90 ? 1167 GLN A CG 1 ATOM 3457 C CD . GLN A 1 451 ? -24.301 2.047 -95.505 1.00 348.98 ? 1167 GLN A CD 1 ATOM 3458 O OE1 . GLN A 1 451 ? -25.332 2.372 -96.093 1.00 351.15 ? 1167 GLN A OE1 1 ATOM 3459 N NE2 . GLN A 1 451 ? -23.090 2.293 -95.994 1.00 351.23 ? 1167 GLN A NE2 1 ATOM 3460 N N . GLN A 1 452 ? -27.982 1.635 -91.375 1.00 336.60 ? 1168 GLN A N 1 ATOM 3461 C CA . GLN A 1 452 ? -28.989 2.319 -90.573 1.00 340.53 ? 1168 GLN A CA 1 ATOM 3462 C C . GLN A 1 452 ? -29.078 1.714 -89.179 1.00 340.04 ? 1168 GLN A C 1 ATOM 3463 O O . GLN A 1 452 ? -29.155 2.437 -88.181 1.00 338.61 ? 1168 GLN A O 1 ATOM 3464 C CB . GLN A 1 452 ? -30.348 2.257 -91.277 1.00 344.03 ? 1168 GLN A CB 1 ATOM 3465 C CG . GLN A 1 452 ? -31.396 3.209 -90.719 1.00 347.66 ? 1168 GLN A CG 1 ATOM 3466 C CD . GLN A 1 452 ? -31.118 4.662 -91.057 1.00 350.45 ? 1168 GLN A CD 1 ATOM 3467 O OE1 . GLN A 1 452 ? -30.262 4.970 -91.887 1.00 351.24 ? 1168 GLN A OE1 1 ATOM 3468 N NE2 . GLN A 1 452 ? -31.846 5.566 -90.412 1.00 352.56 ? 1168 GLN A NE2 1 ATOM 3469 N N . MET A 1 453 ? -29.066 0.382 -89.092 1.00 334.63 ? 1169 MET A N 1 ATOM 3470 C CA . MET A 1 453 ? -29.194 -0.268 -87.795 1.00 332.56 ? 1169 MET A CA 1 ATOM 3471 C C . MET A 1 453 ? -27.979 0.010 -86.923 1.00 327.57 ? 1169 MET A C 1 ATOM 3472 O O . MET A 1 453 ? -28.100 0.153 -85.700 1.00 329.70 ? 1169 MET A O 1 ATOM 3473 C CB . MET A 1 453 ? -29.397 -1.774 -87.980 1.00 337.64 ? 1169 MET A CB 1 ATOM 3474 C CG . MET A 1 453 ? -29.804 -2.506 -86.718 1.00 340.71 ? 1169 MET A CG 1 ATOM 3475 S SD . MET A 1 453 ? -29.562 -4.288 -86.860 1.00 350.24 ? 1169 MET A SD 1 ATOM 3476 C CE . MET A 1 453 ? -30.211 -4.595 -88.501 1.00 348.40 ? 1169 MET A CE 1 ATOM 3477 N N . ALA A 1 454 ? -26.797 0.096 -87.537 1.00 343.76 ? 1170 ALA A N 1 ATOM 3478 C CA . ALA A 1 454 ? -25.599 0.454 -86.786 1.00 338.20 ? 1170 ALA A CA 1 ATOM 3479 C C . ALA A 1 454 ? -25.693 1.879 -86.254 1.00 335.50 ? 1170 ALA A C 1 ATOM 3480 O O . ALA A 1 454 ? -25.368 2.138 -85.088 1.00 336.28 ? 1170 ALA A O 1 ATOM 3481 C CB . ALA A 1 454 ? -24.359 0.284 -87.664 1.00 338.25 ? 1170 ALA A CB 1 ATOM 3482 N N . TYR A 1 455 ? -26.158 2.812 -87.084 1.00 351.36 ? 1171 TYR A N 1 ATOM 3483 C CA . TYR A 1 455 ? -26.345 4.186 -86.628 1.00 350.90 ? 1171 TYR A CA 1 ATOM 3484 C C . TYR A 1 455 ? -27.452 4.291 -85.589 1.00 352.72 ? 1171 TYR A C 1 ATOM 3485 O O . TYR A 1 455 ? -27.364 5.121 -84.679 1.00 350.61 ? 1171 TYR A O 1 ATOM 3486 C CB . TYR A 1 455 ? -26.647 5.095 -87.820 1.00 352.34 ? 1171 TYR A CB 1 ATOM 3487 C CG . TYR A 1 455 ? -27.053 6.500 -87.435 1.00 353.36 ? 1171 TYR A CG 1 ATOM 3488 C CD1 . TYR A 1 455 ? -26.103 7.437 -87.049 1.00 350.83 ? 1171 TYR A CD1 1 ATOM 3489 C CD2 . TYR A 1 455 ? -28.388 6.889 -87.460 1.00 355.99 ? 1171 TYR A CD2 1 ATOM 3490 C CE1 . TYR A 1 455 ? -26.469 8.721 -86.699 1.00 349.24 ? 1171 TYR A CE1 1 ATOM 3491 C CE2 . TYR A 1 455 ? -28.763 8.170 -87.110 1.00 354.61 ? 1171 TYR A CE2 1 ATOM 3492 C CZ . TYR A 1 455 ? -27.800 9.081 -86.731 1.00 351.70 ? 1171 TYR A CZ 1 ATOM 3493 O OH . TYR A 1 455 ? -28.171 10.357 -86.382 1.00 350.10 ? 1171 TYR A OH 1 ATOM 3494 N N . ASN A 1 456 ? -28.497 3.473 -85.707 1.00 335.76 ? 1172 ASN A N 1 ATOM 3495 C CA . ASN A 1 456 ? -29.605 3.548 -84.758 1.00 337.33 ? 1172 ASN A CA 1 ATOM 3496 C C . ASN A 1 456 ? -29.178 3.077 -83.374 1.00 335.40 ? 1172 ASN A C 1 ATOM 3497 O O . ASN A 1 456 ? -29.451 3.745 -82.371 1.00 336.43 ? 1172 ASN A O 1 ATOM 3498 C CB . ASN A 1 456 ? -30.796 2.729 -85.262 1.00 340.04 ? 1172 ASN A CB 1 ATOM 3499 C CG . ASN A 1 456 ? -31.466 3.352 -86.473 1.00 342.53 ? 1172 ASN A CG 1 ATOM 3500 O OD1 . ASN A 1 456 ? -31.439 4.570 -86.654 1.00 348.31 ? 1172 ASN A OD1 1 ATOM 3501 N ND2 . ASN A 1 456 ? -32.071 2.518 -87.312 1.00 342.11 ? 1172 ASN A ND2 1 ATOM 3502 N N . THR A 1 457 ? -28.508 1.925 -83.297 1.00 327.70 ? 1173 THR A N 1 ATOM 3503 C CA . THR A 1 457 ? -28.107 1.390 -81.999 1.00 329.69 ? 1173 THR A CA 1 ATOM 3504 C C . THR A 1 457 ? -27.106 2.305 -81.305 1.00 326.33 ? 1173 THR A C 1 ATOM 3505 O O . THR A 1 457 ? -27.128 2.442 -80.077 1.00 323.28 ? 1173 THR A O 1 ATOM 3506 C CB . THR A 1 457 ? -27.524 -0.015 -82.161 1.00 333.45 ? 1173 THR A CB 1 ATOM 3507 O OG1 . THR A 1 457 ? -26.476 0.012 -83.134 1.00 337.43 ? 1173 THR A OG1 1 ATOM 3508 C CG2 . THR A 1 457 ? -28.605 -0.988 -82.604 1.00 335.51 ? 1173 THR A CG2 1 ATOM 3509 N N . LEU A 1 458 ? -26.226 2.950 -82.075 1.00 337.15 ? 1174 LEU A N 1 ATOM 3510 C CA . LEU A 1 458 ? -25.235 3.838 -81.475 1.00 336.59 ? 1174 LEU A CA 1 ATOM 3511 C C . LEU A 1 458 ? -25.872 5.111 -80.932 1.00 338.07 ? 1174 LEU A C 1 ATOM 3512 O O . LEU A 1 458 ? -25.411 5.649 -79.916 1.00 338.12 ? 1174 LEU A O 1 ATOM 3513 C CB . LEU A 1 458 ? -24.143 4.178 -82.493 1.00 333.78 ? 1174 LEU A CB 1 ATOM 3514 C CG . LEU A 1 458 ? -23.154 3.066 -82.844 1.00 332.81 ? 1174 LEU A CG 1 ATOM 3515 C CD1 . LEU A 1 458 ? -22.124 3.560 -83.850 1.00 334.69 ? 1174 LEU A CD1 1 ATOM 3516 C CD2 . LEU A 1 458 ? -22.472 2.542 -81.590 1.00 331.17 ? 1174 LEU A CD2 1 ATOM 3517 N N . MET A 1 459 ? -26.925 5.604 -81.586 1.00 332.77 ? 1175 MET A N 1 ATOM 3518 C CA . MET A 1 459 ? -27.611 6.812 -81.144 1.00 333.00 ? 1175 MET A CA 1 ATOM 3519 C C . MET A 1 459 ? -28.658 6.544 -80.071 1.00 333.59 ? 1175 MET A C 1 ATOM 3520 O O . MET A 1 459 ? -28.939 7.431 -79.259 1.00 331.86 ? 1175 MET A O 1 ATOM 3521 C CB . MET A 1 459 ? -28.280 7.505 -82.334 1.00 333.71 ? 1175 MET A CB 1 ATOM 3522 C CG . MET A 1 459 ? -27.326 8.006 -83.410 1.00 335.48 ? 1175 MET A CG 1 ATOM 3523 S SD . MET A 1 459 ? -26.606 9.633 -83.101 1.00 339.29 ? 1175 MET A SD 1 ATOM 3524 C CE . MET A 1 459 ? -25.234 9.228 -82.024 1.00 332.46 ? 1175 MET A CE 1 ATOM 3525 N N . GLU A 1 460 ? -29.239 5.342 -80.047 1.00 319.67 ? 1176 GLU A N 1 ATOM 3526 C CA . GLU A 1 460 ? -30.302 5.044 -79.090 1.00 321.92 ? 1176 GLU A CA 1 ATOM 3527 C C . GLU A 1 460 ? -29.786 4.877 -77.665 1.00 315.29 ? 1176 GLU A C 1 ATOM 3528 O O . GLU A 1 460 ? -30.586 4.928 -76.725 1.00 318.01 ? 1176 GLU A O 1 ATOM 3529 C CB . GLU A 1 460 ? -31.055 3.782 -79.517 1.00 330.77 ? 1176 GLU A CB 1 ATOM 3530 C CG . GLU A 1 460 ? -32.049 4.006 -80.643 1.00 340.01 ? 1176 GLU A CG 1 ATOM 3531 C CD . GLU A 1 460 ? -32.491 2.712 -81.296 1.00 347.63 ? 1176 GLU A CD 1 ATOM 3532 O OE1 . GLU A 1 460 ? -32.201 1.632 -80.738 1.00 348.55 ? 1176 GLU A OE1 1 ATOM 3533 O OE2 . GLU A 1 460 ? -33.121 2.776 -82.373 1.00 354.09 ? 1176 GLU A OE2 1 ATOM 3534 N N . VAL A 1 461 ? -28.484 4.680 -77.483 1.00 328.26 ? 1177 VAL A N 1 ATOM 3535 C CA . VAL A 1 461 ? -27.913 4.459 -76.165 1.00 324.49 ? 1177 VAL A CA 1 ATOM 3536 C C . VAL A 1 461 ? -27.217 5.738 -75.704 1.00 322.57 ? 1177 VAL A C 1 ATOM 3537 O O . VAL A 1 461 ? -26.826 6.590 -76.505 1.00 325.02 ? 1177 VAL A O 1 ATOM 3538 C CB . VAL A 1 461 ? -26.945 3.254 -76.156 1.00 324.47 ? 1177 VAL A CB 1 ATOM 3539 C CG1 . VAL A 1 461 ? -25.554 3.663 -76.631 1.00 323.60 ? 1177 VAL A CG1 1 ATOM 3540 C CG2 . VAL A 1 461 ? -26.905 2.600 -74.779 1.00 327.02 ? 1177 VAL A CG2 1 ATOM 3541 N N . SER A 1 462 ? -27.073 5.863 -74.383 1.00 329.51 ? 1178 SER A N 1 ATOM 3542 C CA . SER A 1 462 ? -26.623 7.108 -73.774 1.00 328.02 ? 1178 SER A CA 1 ATOM 3543 C C . SER A 1 462 ? -25.194 7.447 -74.189 1.00 328.18 ? 1178 SER A C 1 ATOM 3544 O O . SER A 1 462 ? -24.446 6.611 -74.702 1.00 332.99 ? 1178 SER A O 1 ATOM 3545 C CB . SER A 1 462 ? -26.716 7.024 -72.249 1.00 327.53 ? 1178 SER A CB 1 ATOM 3546 O OG . SER A 1 462 ? -25.672 6.227 -71.714 1.00 327.12 ? 1178 SER A OG 1 ATOM 3547 N N . ALA A 1 463 ? -24.823 8.708 -73.950 1.00 340.25 ? 1179 ALA A N 1 ATOM 3548 C CA . ALA A 1 463 ? -23.513 9.197 -74.375 1.00 340.17 ? 1179 ALA A CA 1 ATOM 3549 C C . ALA A 1 463 ? -22.386 8.477 -73.650 1.00 340.56 ? 1179 ALA A C 1 ATOM 3550 O O . ALA A 1 463 ? -21.327 8.221 -74.234 1.00 343.98 ? 1179 ALA A O 1 ATOM 3551 C CB . ALA A 1 463 ? -23.423 10.706 -74.152 1.00 341.00 ? 1179 ALA A CB 1 ATOM 3552 N N . SER A 1 464 ? -22.588 8.158 -72.371 1.00 335.48 ? 1180 SER A N 1 ATOM 3553 C CA . SER A 1 464 ? -21.575 7.416 -71.626 1.00 334.20 ? 1180 SER A CA 1 ATOM 3554 C C . SER A 1 464 ? -21.404 6.012 -72.187 1.00 333.21 ? 1180 SER A C 1 ATOM 3555 O O . SER A 1 464 ? -20.276 5.523 -72.326 1.00 333.59 ? 1180 SER A O 1 ATOM 3556 C CB . SER A 1 464 ? -21.948 7.360 -70.144 1.00 336.17 ? 1180 SER A CB 1 ATOM 3557 O OG . SER A 1 464 ? -22.062 8.663 -69.597 1.00 337.01 ? 1180 SER A OG 1 ATOM 3558 N N . MET A 1 465 ? -22.513 5.349 -72.515 1.00 327.30 ? 1181 MET A N 1 ATOM 3559 C CA . MET A 1 465 ? -22.437 4.038 -73.149 1.00 327.67 ? 1181 MET A CA 1 ATOM 3560 C C . MET A 1 465 ? -21.745 4.122 -74.503 1.00 326.93 ? 1181 MET A C 1 ATOM 3561 O O . MET A 1 465 ? -20.935 3.255 -74.846 1.00 326.85 ? 1181 MET A O 1 ATOM 3562 C CB . MET A 1 465 ? -23.837 3.444 -73.297 1.00 329.29 ? 1181 MET A CB 1 ATOM 3563 C CG . MET A 1 465 ? -24.293 2.615 -72.109 1.00 331.24 ? 1181 MET A CG 1 ATOM 3564 S SD . MET A 1 465 ? -23.435 1.032 -72.023 1.00 336.36 ? 1181 MET A SD 1 ATOM 3565 C CE . MET A 1 465 ? -23.890 0.318 -73.602 1.00 335.39 ? 1181 MET A CE 1 ATOM 3566 N N . LEU A 1 466 ? -22.052 5.161 -75.285 1.00 332.78 ? 1182 LEU A N 1 ATOM 3567 C CA . LEU A 1 466 ? -21.378 5.345 -76.566 1.00 331.28 ? 1182 LEU A CA 1 ATOM 3568 C C . LEU A 1 466 ? -19.880 5.543 -76.375 1.00 331.05 ? 1182 LEU A C 1 ATOM 3569 O O . LEU A 1 466 ? -19.072 5.030 -77.157 1.00 330.29 ? 1182 LEU A O 1 ATOM 3570 C CB . LEU A 1 466 ? -21.984 6.530 -77.318 1.00 331.06 ? 1182 LEU A CB 1 ATOM 3571 C CG . LEU A 1 466 ? -21.417 6.795 -78.714 1.00 331.96 ? 1182 LEU A CG 1 ATOM 3572 C CD1 . LEU A 1 466 ? -21.834 5.703 -79.687 1.00 331.26 ? 1182 LEU A CD1 1 ATOM 3573 C CD2 . LEU A 1 466 ? -21.836 8.165 -79.223 1.00 332.08 ? 1182 LEU A CD2 1 ATOM 3574 N N . PHE A 1 467 ? -19.487 6.287 -75.339 1.00 333.01 ? 1183 PHE A N 1 ATOM 3575 C CA . PHE A 1 467 ? -18.066 6.426 -75.040 1.00 333.26 ? 1183 PHE A CA 1 ATOM 3576 C C . PHE A 1 467 ? -17.461 5.095 -74.623 1.00 333.10 ? 1183 PHE A C 1 ATOM 3577 O O . PHE A 1 467 ? -16.270 4.852 -74.856 1.00 334.09 ? 1183 PHE A O 1 ATOM 3578 C CB . PHE A 1 467 ? -17.857 7.477 -73.950 1.00 332.32 ? 1183 PHE A CB 1 ATOM 3579 C CG . PHE A 1 467 ? -16.413 7.779 -73.671 1.00 332.60 ? 1183 PHE A CG 1 ATOM 3580 C CD1 . PHE A 1 467 ? -15.733 8.728 -74.416 1.00 333.95 ? 1183 PHE A CD1 1 ATOM 3581 C CD2 . PHE A 1 467 ? -15.736 7.119 -72.659 1.00 333.53 ? 1183 PHE A CD2 1 ATOM 3582 C CE1 . PHE A 1 467 ? -14.405 9.011 -74.158 1.00 333.65 ? 1183 PHE A CE1 1 ATOM 3583 C CE2 . PHE A 1 467 ? -14.408 7.396 -72.398 1.00 334.21 ? 1183 PHE A CE2 1 ATOM 3584 C CZ . PHE A 1 467 ? -13.742 8.344 -73.147 1.00 332.74 ? 1183 PHE A CZ 1 ATOM 3585 N N . ARG A 1 468 ? -18.264 4.219 -74.021 1.00 333.93 ? 1184 ARG A N 1 ATOM 3586 C CA . ARG A 1 468 ? -17.755 2.924 -73.591 1.00 335.15 ? 1184 ARG A CA 1 ATOM 3587 C C . ARG A 1 468 ? -17.647 1.951 -74.760 1.00 336.57 ? 1184 ARG A C 1 ATOM 3588 O O . ARG A 1 468 ? -16.696 1.164 -74.825 1.00 340.23 ? 1184 ARG A O 1 ATOM 3589 C CB . ARG A 1 468 ? -18.647 2.354 -72.488 1.00 336.19 ? 1184 ARG A CB 1 ATOM 3590 C CG . ARG A 1 468 ? -18.072 1.138 -71.780 1.00 337.62 ? 1184 ARG A CG 1 ATOM 3591 C CD . ARG A 1 468 ? -16.761 1.452 -71.084 1.00 338.10 ? 1184 ARG A CD 1 ATOM 3592 N NE . ARG A 1 468 ? -16.172 0.255 -70.492 1.00 337.56 ? 1184 ARG A NE 1 ATOM 3593 C CZ . ARG A 1 468 ? -14.968 0.213 -69.931 1.00 337.18 ? 1184 ARG A CZ 1 ATOM 3594 N NH1 . ARG A 1 468 ? -14.217 1.304 -69.886 1.00 337.14 ? 1184 ARG A NH1 1 ATOM 3595 N NH2 . ARG A 1 468 ? -14.512 -0.922 -69.418 1.00 337.67 ? 1184 ARG A NH2 1 ATOM 3596 N N . VAL A 1 469 ? -18.602 1.988 -75.695 1.00 334.46 ? 1185 VAL A N 1 ATOM 3597 C CA . VAL A 1 469 ? -18.485 1.128 -76.870 1.00 332.40 ? 1185 VAL A CA 1 ATOM 3598 C C . VAL A 1 469 ? -17.338 1.595 -77.755 1.00 330.48 ? 1185 VAL A C 1 ATOM 3599 O O . VAL A 1 469 ? -16.743 0.795 -78.485 1.00 333.76 ? 1185 VAL A O 1 ATOM 3600 C CB . VAL A 1 469 ? -19.812 1.057 -77.656 1.00 334.26 ? 1185 VAL A CB 1 ATOM 3601 C CG1 . VAL A 1 469 ? -20.978 0.742 -76.726 1.00 334.27 ? 1185 VAL A CG1 1 ATOM 3602 C CG2 . VAL A 1 469 ? -20.058 2.337 -78.445 1.00 336.19 ? 1185 VAL A CG2 1 ATOM 3603 N N . GLN A 1 470 ? -17.000 2.887 -77.704 1.00 332.75 ? 1186 GLN A N 1 ATOM 3604 C CA . GLN A 1 470 ? -15.801 3.363 -78.385 1.00 333.48 ? 1186 GLN A CA 1 ATOM 3605 C C . GLN A 1 470 ? -14.548 2.808 -77.720 1.00 334.17 ? 1186 GLN A C 1 ATOM 3606 O O . GLN A 1 470 ? -13.603 2.397 -78.405 1.00 332.85 ? 1186 GLN A O 1 ATOM 3607 C CB . GLN A 1 470 ? -15.770 4.891 -78.393 1.00 332.86 ? 1186 GLN A CB 1 ATOM 3608 C CG . GLN A 1 470 ? -14.550 5.482 -79.084 1.00 331.83 ? 1186 GLN A CG 1 ATOM 3609 C CD . GLN A 1 470 ? -14.446 6.983 -78.903 1.00 333.29 ? 1186 GLN A CD 1 ATOM 3610 O OE1 . GLN A 1 470 ? -14.644 7.501 -77.805 1.00 332.83 ? 1186 GLN A OE1 1 ATOM 3611 N NE2 . GLN A 1 470 ? -14.138 7.690 -79.985 1.00 335.18 ? 1186 GLN A NE2 1 ATOM 3612 N N . HIS A 1 471 ? -14.527 2.787 -76.387 1.00 329.72 ? 1187 HIS A N 1 ATOM 3613 C CA . HIS A 1 471 ? -13.396 2.218 -75.661 1.00 329.68 ? 1187 HIS A CA 1 ATOM 3614 C C . HIS A 1 471 ? -13.200 0.750 -76.010 1.00 329.31 ? 1187 HIS A C 1 ATOM 3615 O O . HIS A 1 471 ? -12.068 0.293 -76.196 1.00 331.01 ? 1187 HIS A O 1 ATOM 3616 C CB . HIS A 1 471 ? -13.605 2.391 -74.157 1.00 330.36 ? 1187 HIS A CB 1 ATOM 3617 C CG . HIS A 1 471 ? -12.688 1.559 -73.316 1.00 331.32 ? 1187 HIS A CG 1 ATOM 3618 N ND1 . HIS A 1 471 ? -13.064 0.345 -72.783 1.00 331.80 ? 1187 HIS A ND1 1 ATOM 3619 C CD2 . HIS A 1 471 ? -11.413 1.768 -72.914 1.00 331.37 ? 1187 HIS A CD2 1 ATOM 3620 C CE1 . HIS A 1 471 ? -12.059 -0.158 -72.089 1.00 331.06 ? 1187 HIS A CE1 1 ATOM 3621 N NE2 . HIS A 1 471 ? -11.045 0.686 -72.152 1.00 332.90 ? 1187 HIS A NE2 1 ATOM 3622 N N . HIS A 1 472 ? -14.295 -0.003 -76.108 1.00 328.38 ? 1188 HIS A N 1 ATOM 3623 C CA . HIS A 1 472 ? -14.190 -1.421 -76.432 1.00 329.66 ? 1188 HIS A CA 1 ATOM 3624 C C . HIS A 1 472 ? -13.835 -1.632 -77.899 1.00 330.91 ? 1188 HIS A C 1 ATOM 3625 O O . HIS A 1 472 ? -13.028 -2.510 -78.225 1.00 330.67 ? 1188 HIS A O 1 ATOM 3626 C CB . HIS A 1 472 ? -15.494 -2.140 -76.085 1.00 330.47 ? 1188 HIS A CB 1 ATOM 3627 C CG . HIS A 1 472 ? -15.712 -2.317 -74.614 1.00 330.92 ? 1188 HIS A CG 1 ATOM 3628 N ND1 . HIS A 1 472 ? -14.924 -3.141 -73.840 1.00 331.17 ? 1188 HIS A ND1 1 ATOM 3629 C CD2 . HIS A 1 472 ? -16.635 -1.785 -73.778 1.00 332.24 ? 1188 HIS A CD2 1 ATOM 3630 C CE1 . HIS A 1 472 ? -15.348 -3.105 -72.589 1.00 332.65 ? 1188 HIS A CE1 1 ATOM 3631 N NE2 . HIS A 1 472 ? -16.385 -2.289 -72.524 1.00 331.48 ? 1188 HIS A NE2 1 ATOM 3632 N N . TYR A 1 473 ? -14.425 -0.842 -78.798 1.00 328.57 ? 1189 TYR A N 1 ATOM 3633 C CA . TYR A 1 473 ? -14.131 -1.006 -80.219 1.00 327.59 ? 1189 TYR A CA 1 ATOM 3634 C C . TYR A 1 473 ? -12.660 -0.747 -80.509 1.00 329.82 ? 1189 TYR A C 1 ATOM 3635 O O . TYR A 1 473 ? -12.044 -1.456 -81.314 1.00 334.36 ? 1189 TYR A O 1 ATOM 3636 C CB . TYR A 1 473 ? -15.013 -0.081 -81.062 1.00 326.05 ? 1189 TYR A CB 1 ATOM 3637 C CG . TYR A 1 473 ? -14.845 -0.285 -82.552 1.00 326.69 ? 1189 TYR A CG 1 ATOM 3638 C CD1 . TYR A 1 473 ? -13.853 0.383 -83.259 1.00 326.25 ? 1189 TYR A CD1 1 ATOM 3639 C CD2 . TYR A 1 473 ? -15.675 -1.151 -83.251 1.00 327.68 ? 1189 TYR A CD2 1 ATOM 3640 C CE1 . TYR A 1 473 ? -13.694 0.198 -84.616 1.00 326.79 ? 1189 TYR A CE1 1 ATOM 3641 C CE2 . TYR A 1 473 ? -15.523 -1.343 -84.612 1.00 327.84 ? 1189 TYR A CE2 1 ATOM 3642 C CZ . TYR A 1 473 ? -14.530 -0.666 -85.290 1.00 327.07 ? 1189 TYR A CZ 1 ATOM 3643 O OH . TYR A 1 473 ? -14.370 -0.850 -86.644 1.00 324.82 ? 1189 TYR A OH 1 ATOM 3644 N N . ASN A 1 474 ? -12.080 0.267 -79.867 1.00 324.63 ? 1190 ASN A N 1 ATOM 3645 C CA . ASN A 1 474 ? -10.673 0.574 -80.089 1.00 325.13 ? 1190 ASN A CA 1 ATOM 3646 C C . ASN A 1 474 ? -9.754 -0.399 -79.365 1.00 326.05 ? 1190 ASN A C 1 ATOM 3647 O O . ASN A 1 474 ? -8.608 -0.590 -79.785 1.00 327.35 ? 1190 ASN A O 1 ATOM 3648 C CB . ASN A 1 474 ? -10.374 2.011 -79.657 1.00 324.24 ? 1190 ASN A CB 1 ATOM 3649 C CG . ASN A 1 474 ? -11.076 3.036 -80.527 1.00 323.97 ? 1190 ASN A CG 1 ATOM 3650 O OD1 . ASN A 1 474 ? -11.326 2.799 -81.708 1.00 323.66 ? 1190 ASN A OD1 1 ATOM 3651 N ND2 . ASN A 1 474 ? -11.399 4.185 -79.944 1.00 326.66 ? 1190 ASN A ND2 1 ATOM 3652 N N . SER A 1 475 ? -10.234 -1.022 -78.288 1.00 320.02 ? 1191 SER A N 1 ATOM 3653 C CA . SER A 1 475 ? -9.429 -2.020 -77.594 1.00 322.12 ? 1191 SER A CA 1 ATOM 3654 C C . SER A 1 475 ? -9.171 -3.236 -78.472 1.00 323.29 ? 1191 SER A C 1 ATOM 3655 O O . SER A 1 475 ? -8.116 -3.873 -78.362 1.00 325.60 ? 1191 SER A O 1 ATOM 3656 C CB . SER A 1 475 ? -10.119 -2.445 -76.295 1.00 325.00 ? 1191 SER A CB 1 ATOM 3657 O OG . SER A 1 475 ? -10.367 -1.332 -75.451 1.00 328.30 ? 1191 SER A OG 1 ATOM 3658 N N . HIS A 1 476 ? -10.110 -3.565 -79.357 1.00 318.79 ? 1192 HIS A N 1 ATOM 3659 C CA . HIS A 1 476 ? -10.040 -4.776 -80.165 1.00 322.32 ? 1192 HIS A CA 1 ATOM 3660 C C . HIS A 1 476 ? -9.668 -4.511 -81.620 1.00 321.72 ? 1192 HIS A C 1 ATOM 3661 O O . HIS A 1 476 ? -8.764 -5.159 -82.154 1.00 322.39 ? 1192 HIS A O 1 ATOM 3662 C CB . HIS A 1 476 ? -11.381 -5.523 -80.108 1.00 326.28 ? 1192 HIS A CB 1 ATOM 3663 C CG . HIS A 1 476 ? -11.748 -6.016 -78.742 1.00 327.84 ? 1192 HIS A CG 1 ATOM 3664 N ND1 . HIS A 1 476 ? -11.156 -7.119 -78.165 1.00 326.83 ? 1192 HIS A ND1 1 ATOM 3665 C CD2 . HIS A 1 476 ? -12.657 -5.565 -77.845 1.00 329.34 ? 1192 HIS A CD2 1 ATOM 3666 C CE1 . HIS A 1 476 ? -11.678 -7.321 -76.968 1.00 328.21 ? 1192 HIS A CE1 1 ATOM 3667 N NE2 . HIS A 1 476 ? -12.591 -6.392 -76.750 1.00 330.30 ? 1192 HIS A NE2 1 ATOM 3668 N N . TYR A 1 477 ? -10.348 -3.570 -82.276 1.00 321.04 ? 1193 TYR A N 1 ATOM 3669 C CA . TYR A 1 477 ? -10.304 -3.454 -83.730 1.00 322.84 ? 1193 TYR A CA 1 ATOM 3670 C C . TYR A 1 477 ? -9.595 -2.193 -84.213 1.00 325.91 ? 1193 TYR A C 1 ATOM 3671 O O . TYR A 1 477 ? -9.873 -1.721 -85.320 1.00 328.07 ? 1193 TYR A O 1 ATOM 3672 C CB . TYR A 1 477 ? -11.723 -3.496 -84.298 1.00 322.73 ? 1193 TYR A CB 1 ATOM 3673 C CG . TYR A 1 477 ? -12.627 -4.507 -83.632 1.00 321.29 ? 1193 TYR A CG 1 ATOM 3674 C CD1 . TYR A 1 477 ? -12.442 -5.869 -83.829 1.00 321.19 ? 1193 TYR A CD1 1 ATOM 3675 C CD2 . TYR A 1 477 ? -13.676 -4.099 -82.817 1.00 321.20 ? 1193 TYR A CD2 1 ATOM 3676 C CE1 . TYR A 1 477 ? -13.270 -6.797 -83.226 1.00 321.59 ? 1193 TYR A CE1 1 ATOM 3677 C CE2 . TYR A 1 477 ? -14.511 -5.020 -82.211 1.00 320.15 ? 1193 TYR A CE2 1 ATOM 3678 C CZ . TYR A 1 477 ? -14.303 -6.368 -82.419 1.00 319.61 ? 1193 TYR A CZ 1 ATOM 3679 O OH . TYR A 1 477 ? -15.129 -7.289 -81.820 1.00 318.21 ? 1193 TYR A OH 1 ATOM 3680 N N . GLU A 1 478 ? -8.676 -1.642 -83.419 1.00 322.13 ? 1194 GLU A N 1 ATOM 3681 C CA . GLU A 1 478 ? -8.046 -0.385 -83.807 1.00 324.52 ? 1194 GLU A CA 1 ATOM 3682 C C . GLU A 1 478 ? -7.088 -0.548 -84.980 1.00 325.96 ? 1194 GLU A C 1 ATOM 3683 O O . GLU A 1 478 ? -6.829 0.428 -85.691 1.00 322.70 ? 1194 GLU A O 1 ATOM 3684 C CB . GLU A 1 478 ? -7.317 0.233 -82.613 1.00 327.19 ? 1194 GLU A CB 1 ATOM 3685 C CG . GLU A 1 478 ? -6.968 1.702 -82.800 1.00 327.92 ? 1194 GLU A CG 1 ATOM 3686 C CD . GLU A 1 478 ? -6.696 2.413 -81.489 1.00 329.19 ? 1194 GLU A CD 1 ATOM 3687 O OE1 . GLU A 1 478 ? -6.283 1.745 -80.518 1.00 329.10 ? 1194 GLU A OE1 1 ATOM 3688 O OE2 . GLU A 1 478 ? -6.904 3.643 -81.429 1.00 327.56 ? 1194 GLU A OE2 1 ATOM 3689 N N . LYS A 1 479 ? -6.570 -1.755 -85.210 1.00 330.86 ? 1195 LYS A N 1 ATOM 3690 C CA . LYS A 1 479 ? -5.630 -1.956 -86.306 1.00 335.75 ? 1195 LYS A CA 1 ATOM 3691 C C . LYS A 1 479 ? -6.316 -1.921 -87.666 1.00 332.29 ? 1195 LYS A C 1 ATOM 3692 O O . LYS A 1 479 ? -5.660 -1.632 -88.673 1.00 336.24 ? 1195 LYS A O 1 ATOM 3693 C CB . LYS A 1 479 ? -4.886 -3.283 -86.134 1.00 341.55 ? 1195 LYS A CB 1 ATOM 3694 C CG . LYS A 1 479 ? -4.423 -3.568 -84.709 1.00 348.73 ? 1195 LYS A CG 1 ATOM 3695 C CD . LYS A 1 479 ? -3.588 -2.430 -84.140 1.00 352.18 ? 1195 LYS A CD 1 ATOM 3696 C CE . LYS A 1 479 ? -3.308 -2.641 -82.659 1.00 354.59 ? 1195 LYS A CE 1 ATOM 3697 N NZ . LYS A 1 479 ? -2.711 -1.430 -82.031 1.00 356.60 ? 1195 LYS A NZ 1 ATOM 3698 N N . PHE A 1 480 ? -7.616 -2.204 -87.716 1.00 330.01 ? 1196 PHE A N 1 ATOM 3699 C CA . PHE A 1 480 ? -8.378 -2.188 -88.956 1.00 330.46 ? 1196 PHE A CA 1 ATOM 3700 C C . PHE A 1 480 ? -9.194 -0.914 -89.122 1.00 327.48 ? 1196 PHE A C 1 ATOM 3701 O O . PHE A 1 480 ? -10.021 -0.835 -90.036 1.00 332.76 ? 1196 PHE A O 1 ATOM 3702 C CB . PHE A 1 480 ? -9.304 -3.404 -89.027 1.00 336.29 ? 1196 PHE A CB 1 ATOM 3703 C CG . PHE A 1 480 ? -8.614 -4.711 -88.761 1.00 342.82 ? 1196 PHE A CG 1 ATOM 3704 C CD1 . PHE A 1 480 ? -8.006 -5.411 -89.789 1.00 349.32 ? 1196 PHE A CD1 1 ATOM 3705 C CD2 . PHE A 1 480 ? -8.584 -5.246 -87.482 1.00 344.50 ? 1196 PHE A CD2 1 ATOM 3706 C CE1 . PHE A 1 480 ? -7.375 -6.616 -89.548 1.00 353.41 ? 1196 PHE A CE1 1 ATOM 3707 C CE2 . PHE A 1 480 ? -7.954 -6.450 -87.234 1.00 347.09 ? 1196 PHE A CE2 1 ATOM 3708 C CZ . PHE A 1 480 ? -7.349 -7.136 -88.268 1.00 352.35 ? 1196 PHE A CZ 1 ATOM 3709 N N . GLY A 1 481 ? -8.989 0.078 -88.260 1.00 329.42 ? 1197 GLY A N 1 ATOM 3710 C CA . GLY A 1 481 ? -9.739 1.314 -88.350 1.00 326.26 ? 1197 GLY A CA 1 ATOM 3711 C C . GLY A 1 481 ? -10.257 1.817 -87.017 1.00 325.40 ? 1197 GLY A C 1 ATOM 3712 O O . GLY A 1 481 ? -10.994 1.114 -86.317 1.00 326.16 ? 1197 GLY A O 1 ATOM 3713 N N . ASP A 1 482 ? -9.870 3.039 -86.660 1.00 329.10 ? 1198 ASP A N 1 ATOM 3714 C CA . ASP A 1 482 ? -10.370 3.680 -85.454 1.00 328.16 ? 1198 ASP A CA 1 ATOM 3715 C C . ASP A 1 482 ? -11.890 3.798 -85.499 1.00 323.25 ? 1198 ASP A C 1 ATOM 3716 O O . ASP A 1 482 ? -12.489 3.916 -86.571 1.00 323.57 ? 1198 ASP A O 1 ATOM 3717 C CB . ASP A 1 482 ? -9.727 5.061 -85.305 1.00 334.31 ? 1198 ASP A CB 1 ATOM 3718 C CG . ASP A 1 482 ? -10.323 5.867 -84.173 1.00 341.51 ? 1198 ASP A CG 1 ATOM 3719 O OD1 . ASP A 1 482 ? -10.432 5.330 -83.048 1.00 353.11 ? 1198 ASP A OD1 1 ATOM 3720 O OD2 . ASP A 1 482 ? -10.692 7.036 -84.411 1.00 344.70 ? 1198 ASP A OD2 1 ATOM 3721 N N . PHE A 1 483 ? -12.518 3.770 -84.316 1.00 333.95 ? 1199 PHE A N 1 ATOM 3722 C CA . PHE A 1 483 ? -13.980 3.767 -84.235 1.00 332.34 ? 1199 PHE A CA 1 ATOM 3723 C C . PHE A 1 483 ? -14.585 4.955 -84.972 1.00 330.41 ? 1199 PHE A C 1 ATOM 3724 O O . PHE A 1 483 ? -15.526 4.802 -85.759 1.00 326.34 ? 1199 PHE A O 1 ATOM 3725 C CB . PHE A 1 483 ? -14.429 3.763 -82.771 1.00 332.61 ? 1199 PHE A CB 1 ATOM 3726 C CG . PHE A 1 483 ? -15.915 3.898 -82.597 1.00 329.83 ? 1199 PHE A CG 1 ATOM 3727 C CD1 . PHE A 1 483 ? -16.763 2.860 -82.946 1.00 328.64 ? 1199 PHE A CD1 1 ATOM 3728 C CD2 . PHE A 1 483 ? -16.464 5.066 -82.095 1.00 327.56 ? 1199 PHE A CD2 1 ATOM 3729 C CE1 . PHE A 1 483 ? -18.136 2.984 -82.795 1.00 327.10 ? 1199 PHE A CE1 1 ATOM 3730 C CE2 . PHE A 1 483 ? -17.834 5.195 -81.941 1.00 324.64 ? 1199 PHE A CE2 1 ATOM 3731 C CZ . PHE A 1 483 ? -18.670 4.154 -82.290 1.00 325.15 ? 1199 PHE A CZ 1 ATOM 3732 N N . VAL A 1 484 ? -14.054 6.150 -84.726 1.00 341.81 ? 1200 VAL A N 1 ATOM 3733 C CA . VAL A 1 484 ? -14.519 7.338 -85.432 1.00 342.36 ? 1200 VAL A CA 1 ATOM 3734 C C . VAL A 1 484 ? -14.262 7.207 -86.919 1.00 342.03 ? 1200 VAL A C 1 ATOM 3735 O O . VAL A 1 484 ? -15.160 7.387 -87.750 1.00 341.54 ? 1200 VAL A O 1 ATOM 3736 C CB . VAL A 1 484 ? -13.819 8.577 -84.862 1.00 344.35 ? 1200 VAL A CB 1 ATOM 3737 C CG1 . VAL A 1 484 ? -14.214 9.853 -85.635 1.00 343.50 ? 1200 VAL A CG1 1 ATOM 3738 C CG2 . VAL A 1 484 ? -14.172 8.666 -83.414 1.00 345.53 ? 1200 VAL A CG2 1 ATOM 3739 N N . TRP A 1 485 ? -13.010 6.945 -87.267 1.00 340.53 ? 1201 TRP A N 1 ATOM 3740 C CA . TRP A 1 485 ? -12.605 6.920 -88.659 1.00 342.05 ? 1201 TRP A CA 1 ATOM 3741 C C . TRP A 1 485 ? -13.365 5.851 -89.421 1.00 339.23 ? 1201 TRP A C 1 ATOM 3742 O O . TRP A 1 485 ? -13.755 6.059 -90.574 1.00 341.68 ? 1201 TRP A O 1 ATOM 3743 C CB . TRP A 1 485 ? -11.098 6.688 -88.723 1.00 344.97 ? 1201 TRP A CB 1 ATOM 3744 C CG . TRP A 1 485 ? -10.483 6.806 -90.075 1.00 344.78 ? 1201 TRP A CG 1 ATOM 3745 C CD1 . TRP A 1 485 ? -9.968 7.934 -90.648 1.00 345.15 ? 1201 TRP A CD1 1 ATOM 3746 C CD2 . TRP A 1 485 ? -10.272 5.746 -91.016 1.00 345.29 ? 1201 TRP A CD2 1 ATOM 3747 N NE1 . TRP A 1 485 ? -9.463 7.644 -91.893 1.00 347.29 ? 1201 TRP A NE1 1 ATOM 3748 C CE2 . TRP A 1 485 ? -9.637 6.308 -92.142 1.00 347.52 ? 1201 TRP A CE2 1 ATOM 3749 C CE3 . TRP A 1 485 ? -10.566 4.378 -91.020 1.00 346.63 ? 1201 TRP A CE3 1 ATOM 3750 C CZ2 . TRP A 1 485 ? -9.290 5.551 -93.260 1.00 349.77 ? 1201 TRP A CZ2 1 ATOM 3751 C CZ3 . TRP A 1 485 ? -10.220 3.628 -92.131 1.00 347.36 ? 1201 TRP A CZ3 1 ATOM 3752 C CH2 . TRP A 1 485 ? -9.589 4.216 -93.235 1.00 349.63 ? 1201 TRP A CH2 1 ATOM 3753 N N . ARG A 1 486 ? -13.611 4.710 -88.782 1.00 329.41 ? 1202 ARG A N 1 ATOM 3754 C CA . ARG A 1 486 ? -14.312 3.630 -89.463 1.00 331.31 ? 1202 ARG A CA 1 ATOM 3755 C C . ARG A 1 486 ? -15.807 3.905 -89.552 1.00 334.18 ? 1202 ARG A C 1 ATOM 3756 O O . ARG A 1 486 ? -16.455 3.491 -90.521 1.00 338.30 ? 1202 ARG A O 1 ATOM 3757 C CB . ARG A 1 486 ? -14.043 2.302 -88.753 1.00 331.17 ? 1202 ARG A CB 1 ATOM 3758 C CG . ARG A 1 486 ? -14.564 1.080 -89.481 1.00 333.37 ? 1202 ARG A CG 1 ATOM 3759 C CD . ARG A 1 486 ? -13.680 0.701 -90.659 1.00 334.06 ? 1202 ARG A CD 1 ATOM 3760 N NE . ARG A 1 486 ? -14.159 -0.503 -91.334 1.00 335.51 ? 1202 ARG A NE 1 ATOM 3761 C CZ . ARG A 1 486 ? -13.917 -1.741 -90.914 1.00 339.41 ? 1202 ARG A CZ 1 ATOM 3762 N NH1 . ARG A 1 486 ? -13.205 -1.942 -89.814 1.00 342.76 ? 1202 ARG A NH1 1 ATOM 3763 N NH2 . ARG A 1 486 ? -14.389 -2.781 -91.590 1.00 342.24 ? 1202 ARG A NH2 1 ATOM 3764 N N . SER A 1 487 ? -16.368 4.596 -88.558 1.00 334.06 ? 1203 SER A N 1 ATOM 3765 C CA . SER A 1 487 ? -17.768 4.994 -88.632 1.00 334.52 ? 1203 SER A CA 1 ATOM 3766 C C . SER A 1 487 ? -18.001 5.974 -89.770 1.00 336.43 ? 1203 SER A C 1 ATOM 3767 O O . SER A 1 487 ? -19.062 5.955 -90.407 1.00 338.26 ? 1203 SER A O 1 ATOM 3768 C CB . SER A 1 487 ? -18.213 5.611 -87.305 1.00 333.42 ? 1203 SER A CB 1 ATOM 3769 O OG . SER A 1 487 ? -18.361 4.615 -86.308 1.00 334.85 ? 1203 SER A OG 1 ATOM 3770 N N . GLU A 1 488 ? -17.015 6.827 -90.039 1.00 345.47 ? 1204 GLU A N 1 ATOM 3771 C CA . GLU A 1 488 ? -17.109 7.769 -91.145 1.00 348.46 ? 1204 GLU A CA 1 ATOM 3772 C C . GLU A 1 488 ? -17.003 7.068 -92.493 1.00 348.08 ? 1204 GLU A C 1 ATOM 3773 O O . GLU A 1 488 ? -17.656 7.482 -93.457 1.00 348.67 ? 1204 GLU A O 1 ATOM 3774 C CB . GLU A 1 488 ? -16.023 8.835 -90.993 1.00 352.73 ? 1204 GLU A CB 1 ATOM 3775 C CG . GLU A 1 488 ? -16.113 9.939 -92.010 1.00 356.23 ? 1204 GLU A CG 1 ATOM 3776 C CD . GLU A 1 488 ? -15.181 11.091 -91.722 1.00 362.29 ? 1204 GLU A CD 1 ATOM 3777 O OE1 . GLU A 1 488 ? -14.164 10.878 -91.030 1.00 367.48 ? 1204 GLU A OE1 1 ATOM 3778 O OE2 . GLU A 1 488 ? -15.471 12.214 -92.185 1.00 367.58 ? 1204 GLU A OE2 1 ATOM 3779 N N . ASP A 1 489 ? -16.207 6.003 -92.576 1.00 340.17 ? 1205 ASP A N 1 ATOM 3780 C CA . ASP A 1 489 ? -16.073 5.265 -93.830 1.00 342.42 ? 1205 ASP A CA 1 ATOM 3781 C C . ASP A 1 489 ? -17.361 4.529 -94.186 1.00 341.43 ? 1205 ASP A C 1 ATOM 3782 O O . ASP A 1 489 ? -17.760 4.497 -95.357 1.00 344.03 ? 1205 ASP A O 1 ATOM 3783 C CB . ASP A 1 489 ? -14.912 4.272 -93.733 1.00 346.30 ? 1205 ASP A CB 1 ATOM 3784 C CG . ASP A 1 489 ? -13.554 4.945 -93.802 1.00 352.65 ? 1205 ASP A CG 1 ATOM 3785 O OD1 . ASP A 1 489 ? -13.458 6.143 -93.461 1.00 357.55 ? 1205 ASP A OD1 1 ATOM 3786 O OD2 . ASP A 1 489 ? -12.578 4.273 -94.201 1.00 360.54 ? 1205 ASP A OD2 1 ATOM 3787 N N . GLU A 1 490 ? -18.014 3.928 -93.194 1.00 332.04 ? 1206 GLU A N 1 ATOM 3788 C CA . GLU A 1 490 ? -19.142 3.038 -93.432 1.00 332.53 ? 1206 GLU A CA 1 ATOM 3789 C C . GLU A 1 490 ? -20.497 3.730 -93.353 1.00 328.67 ? 1206 GLU A C 1 ATOM 3790 O O . GLU A 1 490 ? -21.431 3.311 -94.043 1.00 331.96 ? 1206 GLU A O 1 ATOM 3791 C CB . GLU A 1 490 ? -19.114 1.873 -92.431 1.00 337.46 ? 1206 GLU A CB 1 ATOM 3792 C CG . GLU A 1 490 ? -17.819 1.065 -92.432 1.00 341.27 ? 1206 GLU A CG 1 ATOM 3793 C CD . GLU A 1 490 ? -17.749 0.060 -93.571 1.00 346.14 ? 1206 GLU A CD 1 ATOM 3794 O OE1 . GLU A 1 490 ? -18.780 -0.165 -94.237 1.00 345.97 ? 1206 GLU A OE1 1 ATOM 3795 O OE2 . GLU A 1 490 ? -16.662 -0.510 -93.800 1.00 352.20 ? 1206 GLU A OE2 1 ATOM 3796 N N . LEU A 1 491 ? -20.629 4.789 -92.550 1.00 340.00 ? 1207 LEU A N 1 ATOM 3797 C CA . LEU A 1 491 ? -21.926 5.407 -92.304 1.00 338.50 ? 1207 LEU A CA 1 ATOM 3798 C C . LEU A 1 491 ? -22.078 6.766 -92.958 1.00 338.31 ? 1207 LEU A C 1 ATOM 3799 O O . LEU A 1 491 ? -23.203 7.252 -93.105 1.00 338.25 ? 1207 LEU A O 1 ATOM 3800 C CB . LEU A 1 491 ? -22.158 5.573 -90.793 1.00 337.74 ? 1207 LEU A CB 1 ATOM 3801 C CG . LEU A 1 491 ? -22.179 4.294 -89.956 1.00 337.70 ? 1207 LEU A CG 1 ATOM 3802 C CD1 . LEU A 1 491 ? -22.490 4.596 -88.490 1.00 338.07 ? 1207 LEU A CD1 1 ATOM 3803 C CD2 . LEU A 1 491 ? -23.187 3.320 -90.529 1.00 338.20 ? 1207 LEU A CD2 1 ATOM 3804 N N . GLY A 1 492 ? -20.995 7.394 -93.354 1.00 357.33 ? 1208 GLY A N 1 ATOM 3805 C CA . GLY A 1 492 ? -21.096 8.756 -93.786 1.00 355.57 ? 1208 GLY A CA 1 ATOM 3806 C C . GLY A 1 492 ? -20.790 9.661 -92.627 1.00 353.53 ? 1208 GLY A C 1 ATOM 3807 O O . GLY A 1 492 ? -20.906 9.285 -91.452 1.00 348.77 ? 1208 GLY A O 1 ATOM 3808 N N . PRO A 1 493 ? -20.312 10.853 -92.935 1.00 369.34 ? 1209 PRO A N 1 ATOM 3809 C CA . PRO A 1 493 ? -19.659 11.659 -91.902 1.00 367.86 ? 1209 PRO A CA 1 ATOM 3810 C C . PRO A 1 493 ? -20.526 12.632 -91.196 1.00 368.71 ? 1209 PRO A C 1 ATOM 3811 O O . PRO A 1 493 ? -20.021 13.239 -90.263 1.00 367.75 ? 1209 PRO A O 1 ATOM 3812 C CB . PRO A 1 493 ? -18.529 12.368 -92.668 1.00 367.65 ? 1209 PRO A CB 1 ATOM 3813 C CG . PRO A 1 493 ? -18.432 11.465 -93.894 1.00 369.60 ? 1209 PRO A CG 1 ATOM 3814 C CD . PRO A 1 493 ? -19.746 11.102 -94.247 1.00 370.01 ? 1209 PRO A CD 1 ATOM 3815 N N . ARG A 1 494 ? -21.776 12.797 -91.571 1.00 367.20 ? 1210 ARG A N 1 ATOM 3816 C CA . ARG A 1 494 ? -22.601 13.563 -90.644 1.00 368.08 ? 1210 ARG A CA 1 ATOM 3817 C C . ARG A 1 494 ? -23.109 12.656 -89.532 1.00 368.24 ? 1210 ARG A C 1 ATOM 3818 O O . ARG A 1 494 ? -23.087 13.025 -88.352 1.00 367.89 ? 1210 ARG A O 1 ATOM 3819 C CB . ARG A 1 494 ? -23.751 14.270 -91.379 1.00 370.17 ? 1210 ARG A CB 1 ATOM 3820 C CG . ARG A 1 494 ? -24.910 13.382 -91.792 1.00 370.44 ? 1210 ARG A CG 1 ATOM 3821 C CD . ARG A 1 494 ? -26.211 14.173 -91.792 1.00 369.35 ? 1210 ARG A CD 1 ATOM 3822 N NE . ARG A 1 494 ? -27.333 13.376 -91.308 1.00 368.17 ? 1210 ARG A NE 1 ATOM 3823 C CZ . ARG A 1 494 ? -28.428 13.886 -90.753 1.00 365.83 ? 1210 ARG A CZ 1 ATOM 3824 N NH1 . ARG A 1 494 ? -29.397 13.082 -90.341 1.00 366.63 ? 1210 ARG A NH1 1 ATOM 3825 N NH2 . ARG A 1 494 ? -28.552 15.198 -90.602 1.00 364.99 ? 1210 ARG A NH2 1 ATOM 3826 N N . LYS A 1 495 ? -23.495 11.432 -89.903 1.00 353.80 ? 1211 LYS A N 1 ATOM 3827 C CA . LYS A 1 495 ? -23.826 10.415 -88.913 1.00 352.63 ? 1211 LYS A CA 1 ATOM 3828 C C . LYS A 1 495 ? -22.642 10.190 -88.005 1.00 350.04 ? 1211 LYS A C 1 ATOM 3829 O O . LYS A 1 495 ? -22.796 10.059 -86.787 1.00 351.63 ? 1211 LYS A O 1 ATOM 3830 C CB . LYS A 1 495 ? -24.212 9.099 -89.598 1.00 355.13 ? 1211 LYS A CB 1 ATOM 3831 C CG . LYS A 1 495 ? -25.526 9.139 -90.343 1.00 358.63 ? 1211 LYS A CG 1 ATOM 3832 C CD . LYS A 1 495 ? -25.905 7.744 -90.804 1.00 363.63 ? 1211 LYS A CD 1 ATOM 3833 C CE . LYS A 1 495 ? -27.114 7.757 -91.717 1.00 367.49 ? 1211 LYS A CE 1 ATOM 3834 N NZ . LYS A 1 495 ? -28.324 8.272 -91.024 1.00 370.04 ? 1211 LYS A NZ 1 ATOM 3835 N N . ALA A 1 496 ? -21.444 10.118 -88.593 1.00 366.91 ? 1212 ALA A N 1 ATOM 3836 C CA . ALA A 1 496 ? -20.225 10.144 -87.805 1.00 365.20 ? 1212 ALA A CA 1 ATOM 3837 C C . ALA A 1 496 ? -20.200 11.358 -86.893 1.00 362.87 ? 1212 ALA A C 1 ATOM 3838 O O . ALA A 1 496 ? -20.356 11.226 -85.677 1.00 363.76 ? 1212 ALA A O 1 ATOM 3839 C CB . ALA A 1 496 ? -19.003 10.071 -88.725 1.00 365.61 ? 1212 ALA A CB 1 ATOM 3840 N N . HIS A 1 497 ? -20.076 12.550 -87.469 1.00 368.22 ? 1213 HIS A N 1 ATOM 3841 C CA . HIS A 1 497 ? -20.066 13.776 -86.666 1.00 372.40 ? 1213 HIS A CA 1 ATOM 3842 C C . HIS A 1 497 ? -21.196 13.832 -85.639 1.00 371.85 ? 1213 HIS A C 1 ATOM 3843 O O . HIS A 1 497 ? -21.019 14.386 -84.546 1.00 373.68 ? 1213 HIS A O 1 ATOM 3844 C CB . HIS A 1 497 ? -20.116 15.027 -87.568 1.00 375.14 ? 1213 HIS A CB 1 ATOM 3845 C CG . HIS A 1 497 ? -18.834 15.309 -88.287 1.00 379.84 ? 1213 HIS A CG 1 ATOM 3846 N ND1 . HIS A 1 497 ? -18.502 14.703 -89.479 1.00 384.70 ? 1213 HIS A ND1 1 ATOM 3847 C CD2 . HIS A 1 497 ? -17.798 16.124 -87.977 1.00 382.24 ? 1213 HIS A CD2 1 ATOM 3848 C CE1 . HIS A 1 497 ? -17.322 15.146 -89.878 1.00 386.38 ? 1213 HIS A CE1 1 ATOM 3849 N NE2 . HIS A 1 497 ? -16.870 16.003 -88.980 1.00 386.20 ? 1213 HIS A NE2 1 ATOM 3850 N N . LEU A 1 498 ? -22.350 13.259 -85.961 1.00 356.50 ? 1214 LEU A N 1 ATOM 3851 C CA . LEU A 1 498 ? -23.414 13.152 -84.971 1.00 354.69 ? 1214 LEU A CA 1 ATOM 3852 C C . LEU A 1 498 ? -23.018 12.215 -83.824 1.00 354.59 ? 1214 LEU A C 1 ATOM 3853 O O . LEU A 1 498 ? -23.175 12.560 -82.646 1.00 354.63 ? 1214 LEU A O 1 ATOM 3854 C CB . LEU A 1 498 ? -24.713 12.674 -85.628 1.00 355.44 ? 1214 LEU A CB 1 ATOM 3855 C CG . LEU A 1 498 ? -25.419 13.698 -86.523 1.00 355.74 ? 1214 LEU A CG 1 ATOM 3856 C CD1 . LEU A 1 498 ? -26.646 13.078 -87.164 1.00 356.95 ? 1214 LEU A CD1 1 ATOM 3857 C CD2 . LEU A 1 498 ? -25.791 14.951 -85.751 1.00 354.28 ? 1214 LEU A CD2 1 ATOM 3858 N N . ILE A 1 499 ? -22.506 11.019 -84.152 1.00 351.26 ? 1215 ILE A N 1 ATOM 3859 C CA . ILE A 1 499 ? -21.977 10.103 -83.141 1.00 351.09 ? 1215 ILE A CA 1 ATOM 3860 C C . ILE A 1 499 ? -20.925 10.796 -82.308 1.00 351.91 ? 1215 ILE A C 1 ATOM 3861 O O . ILE A 1 499 ? -20.909 10.711 -81.059 1.00 351.18 ? 1215 ILE A O 1 ATOM 3862 C CB . ILE A 1 499 ? -21.401 8.846 -83.818 1.00 351.67 ? 1215 ILE A CB 1 ATOM 3863 C CG1 . ILE A 1 499 ? -22.489 7.988 -84.455 1.00 353.86 ? 1215 ILE A CG1 1 ATOM 3864 C CG2 . ILE A 1 499 ? -20.467 8.065 -82.860 1.00 351.63 ? 1215 ILE A CG2 1 ATOM 3865 C CD1 . ILE A 1 499 ? -21.934 6.990 -85.429 1.00 354.83 ? 1215 ILE A CD1 1 ATOM 3866 N N . LEU A 1 500 ? -20.027 11.488 -82.996 1.00 353.60 ? 1216 LEU A N 1 ATOM 3867 C CA . LEU A 1 500 ? -18.883 12.165 -82.384 1.00 360.68 ? 1216 LEU A CA 1 ATOM 3868 C C . LEU A 1 500 ? -19.322 13.287 -81.442 1.00 364.12 ? 1216 LEU A C 1 ATOM 3869 O O . LEU A 1 500 ? -18.786 13.384 -80.340 1.00 366.35 ? 1216 LEU A O 1 ATOM 3870 C CB . LEU A 1 500 ? -18.003 12.699 -83.489 1.00 361.40 ? 1216 LEU A CB 1 ATOM 3871 C CG . LEU A 1 500 ? -17.131 11.464 -83.861 1.00 366.11 ? 1216 LEU A CG 1 ATOM 3872 C CD1 . LEU A 1 500 ? -17.284 10.177 -83.062 1.00 366.78 ? 1216 LEU A CD1 1 ATOM 3873 C CD2 . LEU A 1 500 ? -17.467 11.168 -85.263 1.00 368.80 ? 1216 LEU A CD2 1 ATOM 3874 N N . ARG A 1 501 ? -20.323 14.126 -81.806 1.00 353.71 ? 1217 ARG A N 1 ATOM 3875 C CA . ARG A 1 501 ? -20.795 15.162 -80.874 1.00 356.34 ? 1217 ARG A CA 1 ATOM 3876 C C . ARG A 1 501 ? -21.344 14.557 -79.586 1.00 351.22 ? 1217 ARG A C 1 ATOM 3877 O O . ARG A 1 501 ? -21.208 15.151 -78.513 1.00 352.91 ? 1217 ARG A O 1 ATOM 3878 C CB . ARG A 1 501 ? -21.847 16.022 -81.566 1.00 367.22 ? 1217 ARG A CB 1 ATOM 3879 C CG . ARG A 1 501 ? -22.590 17.032 -80.687 1.00 380.91 ? 1217 ARG A CG 1 ATOM 3880 C CD . ARG A 1 501 ? -23.072 18.184 -81.532 1.00 393.28 ? 1217 ARG A CD 1 ATOM 3881 N NE . ARG A 1 501 ? -23.960 19.025 -80.748 1.00 394.47 ? 1217 ARG A NE 1 ATOM 3882 C CZ . ARG A 1 501 ? -25.266 18.818 -80.645 1.00 384.82 ? 1217 ARG A CZ 1 ATOM 3883 N NH1 . ARG A 1 501 ? -26.007 19.624 -79.905 1.00 386.33 ? 1217 ARG A NH1 1 ATOM 3884 N NH2 . ARG A 1 501 ? -25.831 17.808 -81.292 1.00 381.06 ? 1217 ARG A NH2 1 ATOM 3885 N N . ARG A 1 502 ? -22.024 13.413 -79.682 1.00 339.94 ? 1218 ARG A N 1 ATOM 3886 C CA . ARG A 1 502 ? -22.555 12.751 -78.493 1.00 337.51 ? 1218 ARG A CA 1 ATOM 3887 C C . ARG A 1 502 ? -21.442 12.423 -77.511 1.00 334.48 ? 1218 ARG A C 1 ATOM 3888 O O . ARG A 1 502 ? -21.604 12.578 -76.295 1.00 336.71 ? 1218 ARG A O 1 ATOM 3889 C CB . ARG A 1 502 ? -23.303 11.478 -78.900 1.00 339.61 ? 1218 ARG A CB 1 ATOM 3890 C CG . ARG A 1 502 ? -24.016 10.782 -77.761 1.00 344.10 ? 1218 ARG A CG 1 ATOM 3891 C CD . ARG A 1 502 ? -25.337 11.462 -77.450 1.00 345.88 ? 1218 ARG A CD 1 ATOM 3892 N NE . ARG A 1 502 ? -26.159 11.601 -78.648 1.00 347.24 ? 1218 ARG A NE 1 ATOM 3893 C CZ . ARG A 1 502 ? -26.856 10.610 -79.193 1.00 352.24 ? 1218 ARG A CZ 1 ATOM 3894 N NH1 . ARG A 1 502 ? -26.830 9.401 -78.648 1.00 355.82 ? 1218 ARG A NH1 1 ATOM 3895 N NH2 . ARG A 1 502 ? -27.577 10.825 -80.286 1.00 353.19 ? 1218 ARG A NH2 1 ATOM 3896 N N . LEU A 1 503 ? -20.296 11.976 -78.030 1.00 339.36 ? 1219 LEU A N 1 ATOM 3897 C CA . LEU A 1 503 ? -19.142 11.702 -77.182 1.00 337.98 ? 1219 LEU A CA 1 ATOM 3898 C C . LEU A 1 503 ? -18.658 12.957 -76.469 1.00 343.74 ? 1219 LEU A C 1 ATOM 3899 O O . LEU A 1 503 ? -18.054 12.865 -75.395 1.00 345.83 ? 1219 LEU A O 1 ATOM 3900 C CB . LEU A 1 503 ? -18.023 11.086 -78.023 1.00 334.16 ? 1219 LEU A CB 1 ATOM 3901 C CG . LEU A 1 503 ? -18.380 9.759 -78.696 1.00 333.29 ? 1219 LEU A CG 1 ATOM 3902 C CD1 . LEU A 1 503 ? -17.299 9.325 -79.657 1.00 332.34 ? 1219 LEU A CD1 1 ATOM 3903 C CD2 . LEU A 1 503 ? -18.579 8.703 -77.644 1.00 335.10 ? 1219 LEU A CD2 1 ATOM 3904 N N . GLU A 1 504 ? -18.926 14.133 -77.033 1.00 334.15 ? 1220 GLU A N 1 ATOM 3905 C CA . GLU A 1 504 ? -18.488 15.376 -76.414 1.00 339.87 ? 1220 GLU A CA 1 ATOM 3906 C C . GLU A 1 504 ? -19.341 15.760 -75.221 1.00 339.08 ? 1220 GLU A C 1 ATOM 3907 O O . GLU A 1 504 ? -18.933 16.613 -74.429 1.00 342.95 ? 1220 GLU A O 1 ATOM 3908 C CB . GLU A 1 504 ? -18.525 16.494 -77.438 1.00 347.92 ? 1220 GLU A CB 1 ATOM 3909 C CG . GLU A 1 504 ? -18.125 15.990 -78.781 1.00 353.92 ? 1220 GLU A CG 1 ATOM 3910 C CD . GLU A 1 504 ? -16.757 16.439 -79.178 1.00 361.05 ? 1220 GLU A CD 1 ATOM 3911 O OE1 . GLU A 1 504 ? -16.646 17.120 -80.216 1.00 361.54 ? 1220 GLU A OE1 1 ATOM 3912 O OE2 . GLU A 1 504 ? -15.786 16.132 -78.456 1.00 372.10 ? 1220 GLU A OE2 1 ATOM 3913 N N . ARG A 1 505 ? -20.523 15.177 -75.087 1.00 326.68 ? 1221 ARG A N 1 ATOM 3914 C CA . ARG A 1 505 ? -21.373 15.534 -73.969 1.00 331.23 ? 1221 ARG A CA 1 ATOM 3915 C C . ARG A 1 505 ? -20.968 14.813 -72.695 1.00 326.33 ? 1221 ARG A C 1 ATOM 3916 O O . ARG A 1 505 ? -21.417 15.207 -71.610 1.00 329.76 ? 1221 ARG A O 1 ATOM 3917 C CB . ARG A 1 505 ? -22.837 15.266 -74.335 1.00 336.33 ? 1221 ARG A CB 1 ATOM 3918 C CG . ARG A 1 505 ? -23.299 16.065 -75.551 1.00 342.89 ? 1221 ARG A CG 1 ATOM 3919 C CD . ARG A 1 505 ? -24.685 15.660 -76.020 1.00 348.93 ? 1221 ARG A CD 1 ATOM 3920 N NE . ARG A 1 505 ? -25.731 16.052 -75.079 1.00 354.20 ? 1221 ARG A NE 1 ATOM 3921 C CZ . ARG A 1 505 ? -26.464 15.194 -74.377 1.00 358.89 ? 1221 ARG A CZ 1 ATOM 3922 N NH1 . ARG A 1 505 ? -27.398 15.637 -73.545 1.00 360.11 ? 1221 ARG A NH1 1 ATOM 3923 N NH2 . ARG A 1 505 ? -26.270 13.891 -74.514 1.00 361.14 ? 1221 ARG A NH2 1 ATOM 3924 N N . VAL A 1 506 ? -20.120 13.790 -72.810 1.00 343.71 ? 1222 VAL A N 1 ATOM 3925 C CA . VAL A 1 506 ? -19.552 13.079 -71.665 1.00 341.24 ? 1222 VAL A CA 1 ATOM 3926 C C . VAL A 1 506 ? -18.381 13.887 -71.133 1.00 337.71 ? 1222 VAL A C 1 ATOM 3927 O O . VAL A 1 506 ? -17.351 14.013 -71.805 1.00 338.31 ? 1222 VAL A O 1 ATOM 3928 C CB . VAL A 1 506 ? -19.083 11.669 -72.031 1.00 339.97 ? 1222 VAL A CB 1 ATOM 3929 C CG1 . VAL A 1 506 ? -18.391 11.039 -70.818 1.00 340.76 ? 1222 VAL A CG1 1 ATOM 3930 C CG2 . VAL A 1 506 ? -20.227 10.810 -72.486 1.00 340.91 ? 1222 VAL A CG2 1 ATOM 3931 N N . SER A 1 507 ? -18.509 14.373 -69.906 1.00 346.82 ? 1223 SER A N 1 ATOM 3932 C CA . SER A 1 507 ? -17.385 15.050 -69.279 1.00 345.55 ? 1223 SER A CA 1 ATOM 3933 C C . SER A 1 507 ? -16.196 14.111 -69.258 1.00 346.39 ? 1223 SER A C 1 ATOM 3934 O O . SER A 1 507 ? -16.327 12.907 -69.522 1.00 347.89 ? 1223 SER A O 1 ATOM 3935 C CB . SER A 1 507 ? -17.727 15.504 -67.861 1.00 345.15 ? 1223 SER A CB 1 ATOM 3936 O OG . SER A 1 507 ? -17.623 14.413 -66.956 1.00 345.42 ? 1223 SER A OG 1 ATOM 3937 N N . SER A 1 508 ? -15.031 14.636 -68.935 1.00 349.44 ? 1224 SER A N 1 ATOM 3938 C CA . SER A 1 508 ? -13.877 13.774 -68.969 1.00 352.63 ? 1224 SER A CA 1 ATOM 3939 C C . SER A 1 508 ? -13.385 13.325 -67.611 1.00 355.09 ? 1224 SER A C 1 ATOM 3940 O O . SER A 1 508 ? -12.336 12.687 -67.537 1.00 354.21 ? 1224 SER A O 1 ATOM 3941 C CB . SER A 1 508 ? -12.764 14.448 -69.752 1.00 356.75 ? 1224 SER A CB 1 ATOM 3942 O OG . SER A 1 508 ? -13.378 15.390 -70.608 1.00 362.10 ? 1224 SER A OG 1 ATOM 3943 N N . HIS A 1 509 ? -14.112 13.571 -66.531 1.00 354.58 ? 1225 HIS A N 1 ATOM 3944 C CA . HIS A 1 509 ? -13.843 12.706 -65.392 1.00 360.93 ? 1225 HIS A CA 1 ATOM 3945 C C . HIS A 1 509 ? -14.552 11.399 -65.590 1.00 358.03 ? 1225 HIS A C 1 ATOM 3946 O O . HIS A 1 509 ? -14.059 10.339 -65.197 1.00 359.91 ? 1225 HIS A O 1 ATOM 3947 C CB . HIS A 1 509 ? -14.284 13.353 -64.098 1.00 367.71 ? 1225 HIS A CB 1 ATOM 3948 C CG . HIS A 1 509 ? -13.673 14.683 -63.922 1.00 378.77 ? 1225 HIS A CG 1 ATOM 3949 N ND1 . HIS A 1 509 ? -13.837 15.665 -64.868 1.00 383.21 ? 1225 HIS A ND1 1 ATOM 3950 C CD2 . HIS A 1 509 ? -12.791 15.158 -63.014 1.00 388.22 ? 1225 HIS A CD2 1 ATOM 3951 C CE1 . HIS A 1 509 ? -13.124 16.716 -64.518 1.00 389.62 ? 1225 HIS A CE1 1 ATOM 3952 N NE2 . HIS A 1 509 ? -12.482 16.438 -63.395 1.00 392.31 ? 1225 HIS A NE2 1 ATOM 3953 N N . CYS A 1 510 ? -15.729 11.476 -66.192 1.00 357.56 ? 1226 CYS A N 1 ATOM 3954 C CA . CYS A 1 510 ? -16.380 10.276 -66.666 1.00 355.31 ? 1226 CYS A CA 1 ATOM 3955 C C . CYS A 1 510 ? -15.562 9.651 -67.777 1.00 350.05 ? 1226 CYS A C 1 ATOM 3956 O O . CYS A 1 510 ? -15.279 8.454 -67.752 1.00 350.43 ? 1226 CYS A O 1 ATOM 3957 C CB . CYS A 1 510 ? -17.797 10.611 -67.130 1.00 360.32 ? 1226 CYS A CB 1 ATOM 3958 S SG . CYS A 1 510 ? -18.902 11.046 -65.781 1.00 368.52 ? 1226 CYS A SG 1 ATOM 3959 N N . SER A 1 511 ? -15.137 10.470 -68.743 1.00 354.02 ? 1227 SER A N 1 ATOM 3960 C CA . SER A 1 511 ? -14.359 9.958 -69.864 1.00 354.17 ? 1227 SER A CA 1 ATOM 3961 C C . SER A 1 511 ? -13.042 9.356 -69.395 1.00 353.36 ? 1227 SER A C 1 ATOM 3962 O O . SER A 1 511 ? -12.553 8.387 -69.985 1.00 352.59 ? 1227 SER A O 1 ATOM 3963 C CB . SER A 1 511 ? -14.100 11.069 -70.885 1.00 354.46 ? 1227 SER A CB 1 ATOM 3964 O OG . SER A 1 511 ? -12.763 11.536 -70.777 1.00 361.93 ? 1227 SER A OG 1 ATOM 3965 N N . SER A 1 512 ? -12.460 9.903 -68.328 1.00 347.46 ? 1228 SER A N 1 ATOM 3966 C CA . SER A 1 512 ? -11.297 9.266 -67.723 1.00 345.67 ? 1228 SER A CA 1 ATOM 3967 C C . SER A 1 512 ? -11.690 7.961 -67.045 1.00 343.25 ? 1228 SER A C 1 ATOM 3968 O O . SER A 1 512 ? -11.062 6.921 -67.269 1.00 341.33 ? 1228 SER A O 1 ATOM 3969 C CB . SER A 1 512 ? -10.633 10.215 -66.724 1.00 347.14 ? 1228 SER A CB 1 ATOM 3970 O OG . SER A 1 512 ? -9.625 9.548 -65.991 1.00 348.87 ? 1228 SER A OG 1 ATOM 3971 N N . LEU A 1 513 ? -12.741 7.997 -66.222 1.00 351.57 ? 1229 LEU A N 1 ATOM 3972 C CA . LEU A 1 513 ? -13.192 6.791 -65.535 1.00 350.22 ? 1229 LEU A CA 1 ATOM 3973 C C . LEU A 1 513 ? -13.714 5.747 -66.517 1.00 348.74 ? 1229 LEU A C 1 ATOM 3974 O O . LEU A 1 513 ? -13.542 4.544 -66.292 1.00 347.44 ? 1229 LEU A O 1 ATOM 3975 C CB . LEU A 1 513 ? -14.270 7.143 -64.503 1.00 349.44 ? 1229 LEU A CB 1 ATOM 3976 C CG . LEU A 1 513 ? -13.890 7.939 -63.244 1.00 351.46 ? 1229 LEU A CG 1 ATOM 3977 C CD1 . LEU A 1 513 ? -15.091 8.713 -62.697 1.00 355.32 ? 1229 LEU A CD1 1 ATOM 3978 C CD2 . LEU A 1 513 ? -13.320 7.030 -62.169 1.00 351.28 ? 1229 LEU A CD2 1 ATOM 3979 N N . LEU A 1 514 ? -14.338 6.180 -67.613 1.00 348.18 ? 1230 LEU A N 1 ATOM 3980 C CA . LEU A 1 514 ? -14.908 5.246 -68.578 1.00 347.59 ? 1230 LEU A CA 1 ATOM 3981 C C . LEU A 1 514 ? -13.872 4.651 -69.525 1.00 348.53 ? 1230 LEU A C 1 ATOM 3982 O O . LEU A 1 514 ? -14.242 3.857 -70.396 1.00 347.67 ? 1230 LEU A O 1 ATOM 3983 C CB . LEU A 1 514 ? -16.020 5.927 -69.384 1.00 347.35 ? 1230 LEU A CB 1 ATOM 3984 C CG . LEU A 1 514 ? -17.291 6.317 -68.621 1.00 348.79 ? 1230 LEU A CG 1 ATOM 3985 C CD1 . LEU A 1 514 ? -18.112 7.312 -69.425 1.00 349.96 ? 1230 LEU A CD1 1 ATOM 3986 C CD2 . LEU A 1 514 ? -18.125 5.099 -68.272 1.00 348.97 ? 1230 LEU A CD2 1 ATOM 3987 N N . ARG A 1 515 ? -12.601 5.017 -69.392 1.00 345.31 ? 1231 ARG A N 1 ATOM 3988 C CA . ARG A 1 515 ? -11.523 4.332 -70.090 1.00 342.99 ? 1231 ARG A CA 1 ATOM 3989 C C . ARG A 1 515 ? -10.894 3.235 -69.241 1.00 339.33 ? 1231 ARG A C 1 ATOM 3990 O O . ARG A 1 515 ? -9.862 2.680 -69.630 1.00 338.44 ? 1231 ARG A O 1 ATOM 3991 C CB . ARG A 1 515 ? -10.448 5.329 -70.535 1.00 346.49 ? 1231 ARG A CB 1 ATOM 3992 C CG . ARG A 1 515 ? -10.690 5.930 -71.912 1.00 353.46 ? 1231 ARG A CG 1 ATOM 3993 C CD . ARG A 1 515 ? -9.524 6.803 -72.343 1.00 359.28 ? 1231 ARG A CD 1 ATOM 3994 N NE . ARG A 1 515 ? -9.442 8.029 -71.556 1.00 365.07 ? 1231 ARG A NE 1 ATOM 3995 C CZ . ARG A 1 515 ? -9.931 9.200 -71.950 1.00 369.34 ? 1231 ARG A CZ 1 ATOM 3996 N NH1 . ARG A 1 515 ? -10.532 9.305 -73.127 1.00 373.45 ? 1231 ARG A NH1 1 ATOM 3997 N NH2 . ARG A 1 515 ? -9.815 10.268 -71.172 1.00 368.96 ? 1231 ARG A NH2 1 ATOM 3998 N N . SER A 1 516 ? -11.496 2.916 -68.098 1.00 344.74 ? 1232 SER A N 1 ATOM 3999 C CA . SER A 1 516 ? -10.967 1.886 -67.220 1.00 345.37 ? 1232 SER A CA 1 ATOM 4000 C C . SER A 1 516 ? -11.071 0.514 -67.883 1.00 345.19 ? 1232 SER A C 1 ATOM 4001 O O . SER A 1 516 ? -11.689 0.340 -68.935 1.00 346.45 ? 1232 SER A O 1 ATOM 4002 C CB . SER A 1 516 ? -11.716 1.878 -65.887 1.00 345.88 ? 1232 SER A CB 1 ATOM 4003 O OG . SER A 1 516 ? -11.702 3.154 -65.275 1.00 349.04 ? 1232 SER A OG 1 ATOM 4004 N N . ALA A 1 517 ? -10.453 -0.476 -67.240 1.00 350.07 ? 1233 ALA A N 1 ATOM 4005 C CA . ALA A 1 517 ? -10.534 -1.840 -67.748 1.00 349.31 ? 1233 ALA A CA 1 ATOM 4006 C C . ALA A 1 517 ? -11.926 -2.421 -67.542 1.00 351.72 ? 1233 ALA A C 1 ATOM 4007 O O . ALA A 1 517 ? -12.505 -3.016 -68.459 1.00 354.46 ? 1233 ALA A O 1 ATOM 4008 C CB . ALA A 1 517 ? -9.473 -2.711 -67.078 1.00 348.49 ? 1233 ALA A CB 1 ATOM 4009 N N . TYR A 1 518 ? -12.483 -2.253 -66.345 1.00 352.86 ? 1234 TYR A N 1 ATOM 4010 C CA . TYR A 1 518 ? -13.758 -2.863 -66.005 1.00 351.52 ? 1234 TYR A CA 1 ATOM 4011 C C . TYR A 1 518 ? -14.629 -1.886 -65.234 1.00 352.78 ? 1234 TYR A C 1 ATOM 4012 O O . TYR A 1 518 ? -14.142 -1.139 -64.381 1.00 353.09 ? 1234 TYR A O 1 ATOM 4013 C CB . TYR A 1 518 ? -13.555 -4.144 -65.184 1.00 349.30 ? 1234 TYR A CB 1 ATOM 4014 C CG . TYR A 1 518 ? -12.707 -5.160 -65.903 1.00 348.83 ? 1234 TYR A CG 1 ATOM 4015 C CD1 . TYR A 1 518 ? -13.228 -5.904 -66.951 1.00 349.52 ? 1234 TYR A CD1 1 ATOM 4016 C CD2 . TYR A 1 518 ? -11.380 -5.363 -65.548 1.00 347.46 ? 1234 TYR A CD2 1 ATOM 4017 C CE1 . TYR A 1 518 ? -12.456 -6.828 -67.621 1.00 349.86 ? 1234 TYR A CE1 1 ATOM 4018 C CE2 . TYR A 1 518 ? -10.598 -6.286 -66.213 1.00 346.10 ? 1234 TYR A CE2 1 ATOM 4019 C CZ . TYR A 1 518 ? -11.142 -7.016 -67.248 1.00 347.97 ? 1234 TYR A CZ 1 ATOM 4020 O OH . TYR A 1 518 ? -10.371 -7.938 -67.916 1.00 347.32 ? 1234 TYR A OH 1 ATOM 4021 N N . ILE A 1 519 ? -15.920 -1.900 -65.551 1.00 334.16 ? 1235 ILE A N 1 ATOM 4022 C CA . ILE A 1 519 ? -16.930 -1.117 -64.852 1.00 334.08 ? 1235 ILE A CA 1 ATOM 4023 C C . ILE A 1 519 ? -18.005 -2.081 -64.375 1.00 334.72 ? 1235 ILE A C 1 ATOM 4024 O O . ILE A 1 519 ? -18.695 -2.704 -65.193 1.00 335.89 ? 1235 ILE A O 1 ATOM 4025 C CB . ILE A 1 519 ? -17.534 -0.026 -65.748 1.00 336.05 ? 1235 ILE A CB 1 ATOM 4026 C CG1 . ILE A 1 519 ? -16.427 0.839 -66.351 1.00 338.17 ? 1235 ILE A CG1 1 ATOM 4027 C CG2 . ILE A 1 519 ? -18.513 0.833 -64.959 1.00 338.31 ? 1235 ILE A CG2 1 ATOM 4028 C CD1 . ILE A 1 519 ? -16.930 1.888 -67.302 1.00 340.82 ? 1235 ILE A CD1 1 ATOM 4029 N N . GLN A 1 520 ? -18.139 -2.213 -63.060 1.00 333.01 ? 1236 GLN A N 1 ATOM 4030 C CA . GLN A 1 520 ? -19.133 -3.083 -62.453 1.00 334.93 ? 1236 GLN A CA 1 ATOM 4031 C C . GLN A 1 520 ? -20.069 -2.250 -61.589 1.00 337.83 ? 1236 GLN A C 1 ATOM 4032 O O . GLN A 1 520 ? -19.761 -1.111 -61.229 1.00 338.11 ? 1236 GLN A O 1 ATOM 4033 C CB . GLN A 1 520 ? -18.462 -4.191 -61.631 1.00 334.02 ? 1236 GLN A CB 1 ATOM 4034 C CG . GLN A 1 520 ? -17.335 -4.881 -62.385 1.00 335.63 ? 1236 GLN A CG 1 ATOM 4035 C CD . GLN A 1 520 ? -16.957 -6.221 -61.790 1.00 335.98 ? 1236 GLN A CD 1 ATOM 4036 O OE1 . GLN A 1 520 ? -17.295 -7.271 -62.338 1.00 337.16 ? 1236 GLN A OE1 1 ATOM 4037 N NE2 . GLN A 1 520 ? -16.244 -6.195 -60.671 1.00 335.08 ? 1236 GLN A NE2 1 ATOM 4038 N N . SER A 1 521 ? -21.225 -2.821 -61.265 1.00 319.24 ? 1237 SER A N 1 ATOM 4039 C CA . SER A 1 521 ? -22.299 -2.083 -60.606 1.00 322.67 ? 1237 SER A CA 1 ATOM 4040 C C . SER A 1 521 ? -22.636 -2.736 -59.273 1.00 324.41 ? 1237 SER A C 1 ATOM 4041 O O . SER A 1 521 ? -23.128 -3.869 -59.237 1.00 328.83 ? 1237 SER A O 1 ATOM 4042 C CB . SER A 1 521 ? -23.536 -2.007 -61.501 1.00 322.79 ? 1237 SER A CB 1 ATOM 4043 O OG . SER A 1 521 ? -23.278 -1.237 -62.662 1.00 325.94 ? 1237 SER A OG 1 ATOM 4044 N N . ARG A 1 522 ? -22.367 -2.022 -58.186 1.00 318.82 ? 1238 ARG A N 1 ATOM 4045 C CA . ARG A 1 522 ? -22.890 -2.364 -56.873 1.00 320.93 ? 1238 ARG A CA 1 ATOM 4046 C C . ARG A 1 522 ? -24.059 -1.441 -56.555 1.00 323.92 ? 1238 ARG A C 1 ATOM 4047 O O . ARG A 1 522 ? -24.125 -0.307 -57.036 1.00 322.26 ? 1238 ARG A O 1 ATOM 4048 C CB . ARG A 1 522 ? -21.811 -2.247 -55.793 1.00 318.85 ? 1238 ARG A CB 1 ATOM 4049 C CG . ARG A 1 522 ? -21.390 -0.822 -55.461 1.00 318.27 ? 1238 ARG A CG 1 ATOM 4050 C CD . ARG A 1 522 ? -20.281 -0.807 -54.418 1.00 318.39 ? 1238 ARG A CD 1 ATOM 4051 N NE . ARG A 1 522 ? -19.935 0.547 -53.991 1.00 319.96 ? 1238 ARG A NE 1 ATOM 4052 C CZ . ARG A 1 522 ? -20.471 1.155 -52.938 1.00 321.08 ? 1238 ARG A CZ 1 ATOM 4053 N NH1 . ARG A 1 522 ? -21.379 0.528 -52.204 1.00 322.86 ? 1238 ARG A NH1 1 ATOM 4054 N NH2 . ARG A 1 522 ? -20.100 2.388 -52.616 1.00 320.32 ? 1238 ARG A NH2 1 ATOM 4055 N N . VAL A 1 523 ? -24.995 -1.941 -55.755 1.00 316.67 ? 1239 VAL A N 1 ATOM 4056 C CA . VAL A 1 523 ? -26.190 -1.189 -55.391 1.00 322.77 ? 1239 VAL A CA 1 ATOM 4057 C C . VAL A 1 523 ? -26.210 -1.037 -53.878 1.00 323.90 ? 1239 VAL A C 1 ATOM 4058 O O . VAL A 1 523 ? -26.483 -2.000 -53.149 1.00 323.31 ? 1239 VAL A O 1 ATOM 4059 C CB . VAL A 1 523 ? -27.476 -1.857 -55.894 1.00 325.05 ? 1239 VAL A CB 1 ATOM 4060 C CG1 . VAL A 1 523 ? -28.689 -1.096 -55.385 1.00 325.57 ? 1239 VAL A CG1 1 ATOM 4061 C CG2 . VAL A 1 523 ? -27.482 -1.911 -57.412 1.00 326.43 ? 1239 VAL A CG2 1 ATOM 4062 N N . GLU A 1 524 ? -25.924 0.171 -53.409 1.00 326.01 ? 1240 GLU A N 1 ATOM 4063 C CA . GLU A 1 524 ? -26.033 0.502 -52.000 1.00 325.27 ? 1240 GLU A CA 1 ATOM 4064 C C . GLU A 1 524 ? -27.473 0.883 -51.670 1.00 323.15 ? 1240 GLU A C 1 ATOM 4065 O O . GLU A 1 524 ? -28.191 1.455 -52.496 1.00 322.23 ? 1240 GLU A O 1 ATOM 4066 C CB . GLU A 1 524 ? -25.086 1.656 -51.663 1.00 328.49 ? 1240 GLU A CB 1 ATOM 4067 C CG . GLU A 1 524 ? -24.594 1.709 -50.227 1.00 332.03 ? 1240 GLU A CG 1 ATOM 4068 C CD . GLU A 1 524 ? -23.532 2.777 -50.028 1.00 334.35 ? 1240 GLU A CD 1 ATOM 4069 O OE1 . GLU A 1 524 ? -22.780 2.701 -49.034 1.00 339.11 ? 1240 GLU A OE1 1 ATOM 4070 O OE2 . GLU A 1 524 ? -23.446 3.691 -50.876 1.00 332.74 ? 1240 GLU A OE2 1 ATOM 4071 N N . THR A 1 525 ? -27.901 0.545 -50.456 1.00 318.31 ? 1241 THR A N 1 ATOM 4072 C CA . THR A 1 525 ? -29.218 0.922 -49.955 1.00 313.82 ? 1241 THR A CA 1 ATOM 4073 C C . THR A 1 525 ? -29.039 1.543 -48.578 1.00 314.65 ? 1241 THR A C 1 ATOM 4074 O O . THR A 1 525 ? -28.559 0.878 -47.654 1.00 319.66 ? 1241 THR A O 1 ATOM 4075 C CB . THR A 1 525 ? -30.165 -0.280 -49.893 1.00 309.83 ? 1241 THR A CB 1 ATOM 4076 O OG1 . THR A 1 525 ? -30.419 -0.758 -51.221 1.00 315.89 ? 1241 THR A OG1 1 ATOM 4077 C CG2 . THR A 1 525 ? -31.482 0.114 -49.246 1.00 306.94 ? 1241 THR A CG2 1 ATOM 4078 N N . VAL A 1 526 ? -29.416 2.812 -48.447 1.00 311.09 ? 1242 VAL A N 1 ATOM 4079 C CA . VAL A 1 526 ? -29.098 3.590 -47.252 1.00 311.79 ? 1242 VAL A CA 1 ATOM 4080 C C . VAL A 1 526 ? -30.344 4.293 -46.725 1.00 307.34 ? 1242 VAL A C 1 ATOM 4081 O O . VAL A 1 526 ? -31.267 4.587 -47.499 1.00 300.91 ? 1242 VAL A O 1 ATOM 4082 C CB . VAL A 1 526 ? -27.978 4.602 -47.544 1.00 314.93 ? 1242 VAL A CB 1 ATOM 4083 C CG1 . VAL A 1 526 ? -26.651 3.882 -47.733 1.00 315.83 ? 1242 VAL A CG1 1 ATOM 4084 C CG2 . VAL A 1 526 ? -28.322 5.423 -48.775 1.00 315.94 ? 1242 VAL A CG2 1 ATOM 4085 N N . PRO A 1 527 ? -30.415 4.577 -45.428 1.00 315.68 ? 1243 PRO A N 1 ATOM 4086 C CA . PRO A 1 527 ? -31.588 5.253 -44.871 1.00 314.82 ? 1243 PRO A CA 1 ATOM 4087 C C . PRO A 1 527 ? -31.458 6.772 -44.897 1.00 312.50 ? 1243 PRO A C 1 ATOM 4088 O O . PRO A 1 527 ? -30.366 7.336 -44.939 1.00 311.41 ? 1243 PRO A O 1 ATOM 4089 C CB . PRO A 1 527 ? -31.618 4.737 -43.428 1.00 316.63 ? 1243 PRO A CB 1 ATOM 4090 C CG . PRO A 1 527 ? -30.177 4.557 -43.092 1.00 316.74 ? 1243 PRO A CG 1 ATOM 4091 C CD . PRO A 1 527 ? -29.497 4.115 -44.371 1.00 314.59 ? 1243 PRO A CD 1 ATOM 4092 N N . TYR A 1 528 ? -32.615 7.427 -44.865 1.00 314.24 ? 1244 TYR A N 1 ATOM 4093 C CA . TYR A 1 528 ? -32.666 8.875 -44.748 1.00 312.08 ? 1244 TYR A CA 1 ATOM 4094 C C . TYR A 1 528 ? -33.911 9.261 -43.964 1.00 311.53 ? 1244 TYR A C 1 ATOM 4095 O O . TYR A 1 528 ? -34.952 8.607 -44.057 1.00 308.03 ? 1244 TYR A O 1 ATOM 4096 C CB . TYR A 1 528 ? -32.660 9.567 -46.118 1.00 311.10 ? 1244 TYR A CB 1 ATOM 4097 C CG . TYR A 1 528 ? -33.927 9.389 -46.924 1.00 308.42 ? 1244 TYR A CG 1 ATOM 4098 C CD1 . TYR A 1 528 ? -34.202 8.187 -47.561 1.00 309.59 ? 1244 TYR A CD1 1 ATOM 4099 C CD2 . TYR A 1 528 ? -34.842 10.427 -47.060 1.00 305.41 ? 1244 TYR A CD2 1 ATOM 4100 C CE1 . TYR A 1 528 ? -35.352 8.020 -48.308 1.00 308.80 ? 1244 TYR A CE1 1 ATOM 4101 C CE2 . TYR A 1 528 ? -35.999 10.268 -47.804 1.00 305.82 ? 1244 TYR A CE2 1 ATOM 4102 C CZ . TYR A 1 528 ? -36.247 9.061 -48.426 1.00 307.25 ? 1244 TYR A CZ 1 ATOM 4103 O OH . TYR A 1 528 ? -37.393 8.890 -49.168 1.00 307.92 ? 1244 TYR A OH 1 ATOM 4104 N N . LEU A 1 529 ? -33.785 10.329 -43.183 1.00 303.26 ? 1245 LEU A N 1 ATOM 4105 C CA . LEU A 1 529 ? -34.876 10.798 -42.341 1.00 302.58 ? 1245 LEU A CA 1 ATOM 4106 C C . LEU A 1 529 ? -35.848 11.633 -43.165 1.00 302.46 ? 1245 LEU A C 1 ATOM 4107 O O . LEU A 1 529 ? -35.443 12.575 -43.852 1.00 302.30 ? 1245 LEU A O 1 ATOM 4108 C CB . LEU A 1 529 ? -34.321 11.617 -41.177 1.00 305.12 ? 1245 LEU A CB 1 ATOM 4109 C CG . LEU A 1 529 ? -35.127 11.687 -39.880 1.00 311.28 ? 1245 LEU A CG 1 ATOM 4110 C CD1 . LEU A 1 529 ? -35.183 10.326 -39.208 1.00 314.71 ? 1245 LEU A CD1 1 ATOM 4111 C CD2 . LEU A 1 529 ? -34.518 12.719 -38.948 1.00 313.50 ? 1245 LEU A CD2 1 ATOM 4112 N N . PHE A 1 530 ? -37.132 11.286 -43.094 1.00 305.29 ? 1246 PHE A N 1 ATOM 4113 C CA . PHE A 1 530 ? -38.191 11.990 -43.812 1.00 307.76 ? 1246 PHE A CA 1 ATOM 4114 C C . PHE A 1 530 ? -39.159 12.568 -42.787 1.00 307.03 ? 1246 PHE A C 1 ATOM 4115 O O . PHE A 1 530 ? -39.941 11.829 -42.180 1.00 309.90 ? 1246 PHE A O 1 ATOM 4116 C CB . PHE A 1 530 ? -38.908 11.054 -44.784 1.00 308.85 ? 1246 PHE A CB 1 ATOM 4117 C CG . PHE A 1 530 ? -40.098 11.672 -45.459 1.00 311.38 ? 1246 PHE A CG 1 ATOM 4118 C CD1 . PHE A 1 530 ? -39.931 12.597 -46.476 1.00 313.87 ? 1246 PHE A CD1 1 ATOM 4119 C CD2 . PHE A 1 530 ? -41.385 11.322 -45.084 1.00 313.91 ? 1246 PHE A CD2 1 ATOM 4120 C CE1 . PHE A 1 530 ? -41.025 13.166 -47.100 1.00 315.92 ? 1246 PHE A CE1 1 ATOM 4121 C CE2 . PHE A 1 530 ? -42.482 11.888 -45.706 1.00 313.62 ? 1246 PHE A CE2 1 ATOM 4122 C CZ . PHE A 1 530 ? -42.302 12.811 -46.715 1.00 314.51 ? 1246 PHE A CZ 1 ATOM 4123 N N . CYS A 1 531 ? -39.110 13.884 -42.597 1.00 310.44 ? 1247 CYS A N 1 ATOM 4124 C CA . CYS A 1 531 ? -39.900 14.563 -41.580 1.00 311.09 ? 1247 CYS A CA 1 ATOM 4125 C C . CYS A 1 531 ? -40.890 15.520 -42.227 1.00 308.60 ? 1247 CYS A C 1 ATOM 4126 O O . CYS A 1 531 ? -40.572 16.183 -43.218 1.00 308.69 ? 1247 CYS A O 1 ATOM 4127 C CB . CYS A 1 531 ? -38.997 15.333 -40.607 1.00 314.87 ? 1247 CYS A CB 1 ATOM 4128 S SG . CYS A 1 531 ? -37.724 14.349 -39.762 1.00 324.24 ? 1247 CYS A SG 1 ATOM 4129 N N . ARG A 1 532 ? -42.088 15.588 -41.653 1.00 310.53 ? 1248 ARG A N 1 ATOM 4130 C CA . ARG A 1 532 ? -43.130 16.505 -42.089 1.00 309.20 ? 1248 ARG A CA 1 ATOM 4131 C C . ARG A 1 532 ? -43.652 17.273 -40.884 1.00 306.21 ? 1248 ARG A C 1 ATOM 4132 O O . ARG A 1 532 ? -43.514 16.837 -39.740 1.00 305.69 ? 1248 ARG A O 1 ATOM 4133 C CB . ARG A 1 532 ? -44.279 15.758 -42.785 1.00 310.51 ? 1248 ARG A CB 1 ATOM 4134 C CG . ARG A 1 532 ? -43.858 14.992 -44.029 1.00 314.21 ? 1248 ARG A CG 1 ATOM 4135 C CD . ARG A 1 532 ? -43.490 15.936 -45.159 1.00 317.32 ? 1248 ARG A CD 1 ATOM 4136 N NE . ARG A 1 532 ? -44.656 16.661 -45.652 1.00 320.76 ? 1248 ARG A NE 1 ATOM 4137 C CZ . ARG A 1 532 ? -44.608 17.626 -46.563 1.00 324.58 ? 1248 ARG A CZ 1 ATOM 4138 N NH1 . ARG A 1 532 ? -45.725 18.224 -46.953 1.00 328.00 ? 1248 ARG A NH1 1 ATOM 4139 N NH2 . ARG A 1 532 ? -43.447 17.991 -47.090 1.00 325.46 ? 1248 ARG A NH2 1 ATOM 4140 N N . SER A 1 533 ? -44.257 18.427 -41.150 1.00 309.81 ? 1249 SER A N 1 ATOM 4141 C CA . SER A 1 533 ? -44.745 19.300 -40.090 1.00 312.62 ? 1249 SER A CA 1 ATOM 4142 C C . SER A 1 533 ? -46.176 18.922 -39.728 1.00 317.75 ? 1249 SER A C 1 ATOM 4143 O O . SER A 1 533 ? -47.068 18.951 -40.581 1.00 314.99 ? 1249 SER A O 1 ATOM 4144 C CB . SER A 1 533 ? -44.673 20.765 -40.518 1.00 314.32 ? 1249 SER A CB 1 ATOM 4145 O OG . SER A 1 533 ? -45.118 21.620 -39.479 1.00 317.38 ? 1249 SER A OG 1 ATOM 4146 N N . GLU A 1 534 ? -46.388 18.565 -38.462 1.00 321.97 ? 1250 GLU A N 1 ATOM 4147 C CA . GLU A 1 534 ? -47.743 18.356 -37.959 1.00 330.63 ? 1250 GLU A CA 1 ATOM 4148 C C . GLU A 1 534 ? -48.470 19.684 -37.792 1.00 331.08 ? 1250 GLU A C 1 ATOM 4149 O O . GLU A 1 534 ? -49.582 19.869 -38.301 1.00 335.78 ? 1250 GLU A O 1 ATOM 4150 C CB . GLU A 1 534 ? -47.696 17.617 -36.620 1.00 336.78 ? 1250 GLU A CB 1 ATOM 4151 C CG . GLU A 1 534 ? -47.244 16.175 -36.705 1.00 341.08 ? 1250 GLU A CG 1 ATOM 4152 C CD . GLU A 1 534 ? -48.396 15.224 -36.945 1.00 344.95 ? 1250 GLU A CD 1 ATOM 4153 O OE1 . GLU A 1 534 ? -49.534 15.559 -36.552 1.00 345.39 ? 1250 GLU A OE1 1 ATOM 4154 O OE2 . GLU A 1 534 ? -48.166 14.144 -37.526 1.00 350.00 ? 1250 GLU A OE2 1 ATOM 4155 N N . GLU A 1 535 ? -47.847 20.622 -37.088 1.00 329.78 ? 1251 GLU A N 1 ATOM 4156 C CA . GLU A 1 535 ? -48.500 21.828 -36.599 1.00 332.25 ? 1251 GLU A CA 1 ATOM 4157 C C . GLU A 1 535 ? -47.988 23.033 -37.375 1.00 329.21 ? 1251 GLU A C 1 ATOM 4158 O O . GLU A 1 535 ? -46.785 23.319 -37.353 1.00 334.24 ? 1251 GLU A O 1 ATOM 4159 C CB . GLU A 1 535 ? -48.234 21.985 -35.100 1.00 337.56 ? 1251 GLU A CB 1 ATOM 4160 C CG . GLU A 1 535 ? -48.637 23.315 -34.495 1.00 342.20 ? 1251 GLU A CG 1 ATOM 4161 C CD . GLU A 1 535 ? -48.042 23.508 -33.115 1.00 342.73 ? 1251 GLU A CD 1 ATOM 4162 O OE1 . GLU A 1 535 ? -46.802 23.409 -32.984 1.00 337.00 ? 1251 GLU A OE1 1 ATOM 4163 O OE2 . GLU A 1 535 ? -48.811 23.738 -32.158 1.00 345.20 ? 1251 GLU A OE2 1 ATOM 4164 N N . VAL A 1 536 ? -48.888 23.730 -38.061 1.00 334.79 ? 1252 VAL A N 1 ATOM 4165 C CA . VAL A 1 536 ? -48.528 24.994 -38.693 1.00 332.96 ? 1252 VAL A CA 1 ATOM 4166 C C . VAL A 1 536 ? -48.470 26.062 -37.602 1.00 329.34 ? 1252 VAL A C 1 ATOM 4167 O O . VAL A 1 536 ? -49.417 26.229 -36.824 1.00 325.33 ? 1252 VAL A O 1 ATOM 4168 C CB . VAL A 1 536 ? -49.509 25.366 -39.818 1.00 335.24 ? 1252 VAL A CB 1 ATOM 4169 C CG1 . VAL A 1 536 ? -50.929 25.568 -39.297 1.00 336.01 ? 1252 VAL A CG1 1 ATOM 4170 C CG2 . VAL A 1 536 ? -49.016 26.601 -40.568 1.00 333.57 ? 1252 VAL A CG2 1 ATOM 4171 N N . ARG A 1 537 ? -47.346 26.754 -37.520 1.00 329.64 ? 1253 ARG A N 1 ATOM 4172 C CA . ARG A 1 537 ? -47.052 27.584 -36.360 1.00 328.48 ? 1253 ARG A CA 1 ATOM 4173 C C . ARG A 1 537 ? -47.537 29.017 -36.562 1.00 322.17 ? 1253 ARG A C 1 ATOM 4174 O O . ARG A 1 537 ? -47.574 29.513 -37.691 1.00 321.39 ? 1253 ARG A O 1 ATOM 4175 C CB . ARG A 1 537 ? -45.552 27.584 -36.082 1.00 333.12 ? 1253 ARG A CB 1 ATOM 4176 C CG . ARG A 1 537 ? -45.020 26.258 -35.567 1.00 336.07 ? 1253 ARG A CG 1 ATOM 4177 C CD . ARG A 1 537 ? -45.282 26.103 -34.078 1.00 338.28 ? 1253 ARG A CD 1 ATOM 4178 N NE . ARG A 1 537 ? -44.415 26.974 -33.289 1.00 337.81 ? 1253 ARG A NE 1 ATOM 4179 C CZ . ARG A 1 537 ? -44.486 27.106 -31.969 1.00 339.12 ? 1253 ARG A CZ 1 ATOM 4180 N NH1 . ARG A 1 537 ? -45.391 26.428 -31.277 1.00 337.85 ? 1253 ARG A NH1 1 ATOM 4181 N NH2 . ARG A 1 537 ? -43.651 27.922 -31.339 1.00 340.86 ? 1253 ARG A NH2 1 ATOM 4182 N N . PRO A 1 538 ? -47.911 29.700 -35.479 1.00 339.13 ? 1254 PRO A N 1 ATOM 4183 C CA . PRO A 1 538 ? -48.397 31.079 -35.612 1.00 337.69 ? 1254 PRO A CA 1 ATOM 4184 C C . PRO A 1 538 ? -47.251 32.038 -35.902 1.00 335.46 ? 1254 PRO A C 1 ATOM 4185 O O . PRO A 1 538 ? -46.236 32.046 -35.204 1.00 339.41 ? 1254 PRO A O 1 ATOM 4186 C CB . PRO A 1 538 ? -49.039 31.362 -34.248 1.00 336.68 ? 1254 PRO A CB 1 ATOM 4187 C CG . PRO A 1 538 ? -48.289 30.482 -33.306 1.00 337.01 ? 1254 PRO A CG 1 ATOM 4188 C CD . PRO A 1 538 ? -47.952 29.233 -34.081 1.00 339.80 ? 1254 PRO A CD 1 ATOM 4189 N N . ALA A 1 539 ? -47.423 32.844 -36.943 1.00 340.51 ? 1255 ALA A N 1 ATOM 4190 C CA . ALA A 1 539 ? -46.444 33.847 -37.328 1.00 339.09 ? 1255 ALA A CA 1 ATOM 4191 C C . ALA A 1 539 ? -47.123 35.204 -37.423 1.00 336.44 ? 1255 ALA A C 1 ATOM 4192 O O . ALA A 1 539 ? -48.272 35.303 -37.865 1.00 336.00 ? 1255 ALA A O 1 ATOM 4193 C CB . ALA A 1 539 ? -45.780 33.495 -38.663 1.00 340.92 ? 1255 ALA A CB 1 ATOM 4194 N N . GLY A 1 540 ? -46.417 36.241 -36.995 1.00 346.15 ? 1256 GLY A N 1 ATOM 4195 C CA . GLY A 1 540 ? -46.902 37.601 -37.087 1.00 346.41 ? 1256 GLY A CA 1 ATOM 4196 C C . GLY A 1 540 ? -46.468 38.262 -38.375 1.00 348.97 ? 1256 GLY A C 1 ATOM 4197 O O . GLY A 1 540 ? -46.102 37.606 -39.354 1.00 353.38 ? 1256 GLY A O 1 ATOM 4198 N N . MET A 1 541 ? -46.519 39.592 -38.375 1.00 347.50 ? 1257 MET A N 1 ATOM 4199 C CA . MET A 1 541 ? -45.996 40.343 -39.509 1.00 348.86 ? 1257 MET A CA 1 ATOM 4200 C C . MET A 1 541 ? -44.515 40.658 -39.336 1.00 350.04 ? 1257 MET A C 1 ATOM 4201 O O . MET A 1 541 ? -43.717 40.419 -40.243 1.00 352.69 ? 1257 MET A O 1 ATOM 4202 C CB . MET A 1 541 ? -46.797 41.633 -39.717 1.00 351.93 ? 1257 MET A CB 1 ATOM 4203 C CG . MET A 1 541 ? -46.251 42.517 -40.834 1.00 354.25 ? 1257 MET A CG 1 ATOM 4204 S SD . MET A 1 541 ? -47.374 43.830 -41.351 1.00 356.54 ? 1257 MET A SD 1 ATOM 4205 C CE . MET A 1 541 ? -48.691 42.872 -42.094 1.00 355.52 ? 1257 MET A CE 1 ATOM 4206 N N . VAL A 1 542 ? -44.124 41.181 -38.174 1.00 348.57 ? 1258 VAL A N 1 ATOM 4207 C CA . VAL A 1 542 ? -42.731 41.553 -37.955 1.00 347.30 ? 1258 VAL A CA 1 ATOM 4208 C C . VAL A 1 542 ? -41.948 40.468 -37.217 1.00 343.80 ? 1258 VAL A C 1 ATOM 4209 O O . VAL A 1 542 ? -40.705 40.498 -37.222 1.00 347.11 ? 1258 VAL A O 1 ATOM 4210 C CB . VAL A 1 542 ? -42.654 42.912 -37.223 1.00 349.76 ? 1258 VAL A CB 1 ATOM 4211 C CG1 . VAL A 1 542 ? -41.226 43.425 -37.138 1.00 355.24 ? 1258 VAL A CG1 1 ATOM 4212 C CG2 . VAL A 1 542 ? -43.519 43.929 -37.959 1.00 350.49 ? 1258 VAL A CG2 1 ATOM 4213 N N . TRP A 1 543 ? -42.627 39.483 -36.636 1.00 352.70 ? 1259 TRP A N 1 ATOM 4214 C CA . TRP A 1 543 ? -41.988 38.380 -35.935 1.00 350.33 ? 1259 TRP A CA 1 ATOM 4215 C C . TRP A 1 543 ? -42.468 37.059 -36.518 1.00 346.70 ? 1259 TRP A C 1 ATOM 4216 O O . TRP A 1 543 ? -43.555 36.975 -37.096 1.00 346.69 ? 1259 TRP A O 1 ATOM 4217 C CB . TRP A 1 543 ? -42.304 38.426 -34.439 1.00 352.25 ? 1259 TRP A CB 1 ATOM 4218 C CG . TRP A 1 543 ? -43.766 38.278 -34.174 1.00 351.88 ? 1259 TRP A CG 1 ATOM 4219 C CD1 . TRP A 1 543 ? -44.691 39.278 -34.097 1.00 349.39 ? 1259 TRP A CD1 1 ATOM 4220 C CD2 . TRP A 1 543 ? -44.480 37.053 -33.976 1.00 353.18 ? 1259 TRP A CD2 1 ATOM 4221 N NE1 . TRP A 1 543 ? -45.936 38.751 -33.849 1.00 349.69 ? 1259 TRP A NE1 1 ATOM 4222 C CE2 . TRP A 1 543 ? -45.834 37.387 -33.772 1.00 350.39 ? 1259 TRP A CE2 1 ATOM 4223 C CE3 . TRP A 1 543 ? -44.106 35.705 -33.947 1.00 356.67 ? 1259 TRP A CE3 1 ATOM 4224 C CZ2 . TRP A 1 543 ? -46.813 36.422 -33.542 1.00 352.79 ? 1259 TRP A CZ2 1 ATOM 4225 C CZ3 . TRP A 1 543 ? -45.080 34.750 -33.719 1.00 357.83 ? 1259 TRP A CZ3 1 ATOM 4226 C CH2 . TRP A 1 543 ? -46.417 35.113 -33.519 1.00 355.99 ? 1259 TRP A CH2 1 ATOM 4227 N N . TYR A 1 544 ? -41.659 36.017 -36.343 1.00 347.39 ? 1260 TYR A N 1 ATOM 4228 C CA . TYR A 1 544 ? -41.996 34.696 -36.856 1.00 347.79 ? 1260 TYR A CA 1 ATOM 4229 C C . TYR A 1 544 ? -41.818 33.638 -35.779 1.00 347.35 ? 1260 TYR A C 1 ATOM 4230 O O . TYR A 1 544 ? -41.304 33.898 -34.687 1.00 347.52 ? 1260 TYR A O 1 ATOM 4231 C CB . TYR A 1 544 ? -41.145 34.319 -38.067 1.00 348.15 ? 1260 TYR A CB 1 ATOM 4232 C CG . TYR A 1 544 ? -40.936 35.446 -39.018 1.00 350.42 ? 1260 TYR A CG 1 ATOM 4233 C CD1 . TYR A 1 544 ? -42.013 36.088 -39.605 1.00 352.46 ? 1260 TYR A CD1 1 ATOM 4234 C CD2 . TYR A 1 544 ? -39.658 35.861 -39.336 1.00 352.84 ? 1260 TYR A CD2 1 ATOM 4235 C CE1 . TYR A 1 544 ? -41.819 37.119 -40.477 1.00 352.39 ? 1260 TYR A CE1 1 ATOM 4236 C CE2 . TYR A 1 544 ? -39.450 36.883 -40.204 1.00 354.61 ? 1260 TYR A CE2 1 ATOM 4237 C CZ . TYR A 1 544 ? -40.530 37.504 -40.767 1.00 353.73 ? 1260 TYR A CZ 1 ATOM 4238 O OH . TYR A 1 544 ? -40.297 38.524 -41.636 1.00 357.47 ? 1260 TYR A OH 1 ATOM 4239 N N . SER A 1 545 ? -42.240 32.426 -36.129 1.00 334.29 ? 1261 SER A N 1 ATOM 4240 C CA . SER A 1 545 ? -42.223 31.277 -35.240 1.00 336.36 ? 1261 SER A CA 1 ATOM 4241 C C . SER A 1 545 ? -40.856 30.603 -35.221 1.00 335.64 ? 1261 SER A C 1 ATOM 4242 O O . SER A 1 545 ? -40.151 30.545 -36.233 1.00 334.31 ? 1261 SER A O 1 ATOM 4243 C CB . SER A 1 545 ? -43.285 30.266 -35.668 1.00 338.39 ? 1261 SER A CB 1 ATOM 4244 O OG . SER A 1 545 ? -43.102 29.873 -37.020 1.00 340.46 ? 1261 SER A OG 1 ATOM 4245 N N . ILE A 1 546 ? -40.503 30.067 -34.055 1.00 321.06 ? 1262 ILE A N 1 ATOM 4246 C CA . ILE A 1 546 ? -39.225 29.385 -33.875 1.00 316.95 ? 1262 ILE A CA 1 ATOM 4247 C C . ILE A 1 546 ? -39.289 28.030 -34.569 1.00 315.24 ? 1262 ILE A C 1 ATOM 4248 O O . ILE A 1 546 ? -40.177 27.216 -34.292 1.00 315.12 ? 1262 ILE A O 1 ATOM 4249 C CB . ILE A 1 546 ? -38.896 29.239 -32.383 1.00 316.07 ? 1262 ILE A CB 1 ATOM 4250 C CG1 . ILE A 1 546 ? -38.865 30.620 -31.722 1.00 314.88 ? 1262 ILE A CG1 1 ATOM 4251 C CG2 . ILE A 1 546 ? -37.571 28.512 -32.191 1.00 318.58 ? 1262 ILE A CG2 1 ATOM 4252 C CD1 . ILE A 1 546 ? -38.910 30.586 -30.210 1.00 316.30 ? 1262 ILE A CD1 1 ATOM 4253 N N . LEU A 1 547 ? -38.350 27.789 -35.484 1.00 310.55 ? 1263 LEU A N 1 ATOM 4254 C CA . LEU A 1 547 ? -38.361 26.551 -36.261 1.00 311.76 ? 1263 LEU A CA 1 ATOM 4255 C C . LEU A 1 547 ? -38.113 25.332 -35.384 1.00 315.34 ? 1263 LEU A C 1 ATOM 4256 O O . LEU A 1 547 ? -38.666 24.257 -35.644 1.00 312.42 ? 1263 LEU A O 1 ATOM 4257 C CB . LEU A 1 547 ? -37.315 26.628 -37.376 1.00 310.34 ? 1263 LEU A CB 1 ATOM 4258 C CG . LEU A 1 547 ? -37.056 25.369 -38.202 1.00 309.61 ? 1263 LEU A CG 1 ATOM 4259 C CD1 . LEU A 1 547 ? -38.312 24.944 -38.945 1.00 311.94 ? 1263 LEU A CD1 1 ATOM 4260 C CD2 . LEU A 1 547 ? -35.899 25.580 -39.169 1.00 310.25 ? 1263 LEU A CD2 1 ATOM 4261 N N . LYS A 1 548 ? -37.296 25.483 -34.341 1.00 297.85 ? 1264 LYS A N 1 ATOM 4262 C CA . LYS A 1 548 ? -36.957 24.350 -33.488 1.00 302.16 ? 1264 LYS A CA 1 ATOM 4263 C C . LYS A 1 548 ? -38.173 23.826 -32.738 1.00 304.27 ? 1264 LYS A C 1 ATOM 4264 O O . LYS A 1 548 ? -38.266 22.623 -32.467 1.00 305.19 ? 1264 LYS A O 1 ATOM 4265 C CB . LYS A 1 548 ? -35.858 24.758 -32.506 1.00 304.89 ? 1264 LYS A CB 1 ATOM 4266 C CG . LYS A 1 548 ? -35.074 23.608 -31.902 1.00 307.76 ? 1264 LYS A CG 1 ATOM 4267 C CD . LYS A 1 548 ? -34.150 24.113 -30.803 1.00 312.49 ? 1264 LYS A CD 1 ATOM 4268 C CE . LYS A 1 548 ? -33.002 23.152 -30.554 1.00 316.13 ? 1264 LYS A CE 1 ATOM 4269 N NZ . LYS A 1 548 ? -32.012 23.158 -31.668 1.00 319.45 ? 1264 LYS A NZ 1 ATOM 4270 N N . ASP A 1 549 ? -39.114 24.708 -32.402 1.00 311.08 ? 1265 ASP A N 1 ATOM 4271 C CA . ASP A 1 549 ? -40.293 24.313 -31.644 1.00 311.77 ? 1265 ASP A CA 1 ATOM 4272 C C . ASP A 1 549 ? -41.357 23.643 -32.502 1.00 308.82 ? 1265 ASP A C 1 ATOM 4273 O O . ASP A 1 549 ? -42.269 23.016 -31.952 1.00 310.64 ? 1265 ASP A O 1 ATOM 4274 C CB . ASP A 1 549 ? -40.894 25.533 -30.942 1.00 314.27 ? 1265 ASP A CB 1 ATOM 4275 C CG . ASP A 1 549 ? -39.969 26.115 -29.892 1.00 319.26 ? 1265 ASP A CG 1 ATOM 4276 O OD1 . ASP A 1 549 ? -38.805 25.670 -29.803 1.00 323.01 ? 1265 ASP A OD1 1 ATOM 4277 O OD2 . ASP A 1 549 ? -40.407 27.026 -29.158 1.00 321.60 ? 1265 ASP A OD2 1 ATOM 4278 N N . THR A 1 550 ? -41.264 23.766 -33.823 1.00 306.57 ? 1266 THR A N 1 ATOM 4279 C CA . THR A 1 550 ? -42.239 23.160 -34.722 1.00 307.22 ? 1266 THR A CA 1 ATOM 4280 C C . THR A 1 550 ? -42.318 21.657 -34.497 1.00 310.69 ? 1266 THR A C 1 ATOM 4281 O O . THR A 1 550 ? -41.320 20.944 -34.637 1.00 313.76 ? 1266 THR A O 1 ATOM 4282 C CB . THR A 1 550 ? -41.866 23.454 -36.178 1.00 307.19 ? 1266 THR A CB 1 ATOM 4283 O OG1 . THR A 1 550 ? -41.838 24.870 -36.391 1.00 304.50 ? 1266 THR A OG1 1 ATOM 4284 C CG2 . THR A 1 550 ? -42.875 22.822 -37.126 1.00 307.81 ? 1266 THR A CG2 1 ATOM 4285 N N . LYS A 1 551 ? -43.507 21.178 -34.138 1.00 308.52 ? 1267 LYS A N 1 ATOM 4286 C CA . LYS A 1 551 ? -43.702 19.751 -33.930 1.00 312.58 ? 1267 LYS A CA 1 ATOM 4287 C C . LYS A 1 551 ? -43.698 19.032 -35.273 1.00 312.60 ? 1267 LYS A C 1 ATOM 4288 O O . LYS A 1 551 ? -44.436 19.404 -36.191 1.00 310.96 ? 1267 LYS A O 1 ATOM 4289 C CB . LYS A 1 551 ? -45.015 19.490 -33.190 1.00 317.95 ? 1267 LYS A CB 1 ATOM 4290 C CG . LYS A 1 551 ? -45.242 20.379 -31.972 1.00 323.95 ? 1267 LYS A CG 1 ATOM 4291 C CD . LYS A 1 551 ? -44.045 20.378 -31.028 1.00 329.08 ? 1267 LYS A CD 1 ATOM 4292 C CE . LYS A 1 551 ? -43.802 19.008 -30.415 1.00 333.65 ? 1267 LYS A CE 1 ATOM 4293 N NZ . LYS A 1 551 ? -42.574 19.001 -29.572 1.00 336.39 ? 1267 LYS A NZ 1 ATOM 4294 N N . ILE A 1 552 ? -42.858 18.006 -35.394 1.00 309.19 ? 1268 ILE A N 1 ATOM 4295 C CA . ILE A 1 552 ? -42.689 17.285 -36.647 1.00 308.76 ? 1268 ILE A CA 1 ATOM 4296 C C . ILE A 1 552 ? -42.786 15.788 -36.389 1.00 306.59 ? 1268 ILE A C 1 ATOM 4297 O O . ILE A 1 552 ? -42.489 15.304 -35.293 1.00 304.06 ? 1268 ILE A O 1 ATOM 4298 C CB . ILE A 1 552 ? -41.347 17.630 -37.333 1.00 311.10 ? 1268 ILE A CB 1 ATOM 4299 C CG1 . ILE A 1 552 ? -40.174 17.344 -36.392 1.00 309.68 ? 1268 ILE A CG1 1 ATOM 4300 C CG2 . ILE A 1 552 ? -41.333 19.085 -37.783 1.00 313.29 ? 1268 ILE A CG2 1 ATOM 4301 C CD1 . ILE A 1 552 ? -38.820 17.606 -37.012 1.00 307.95 ? 1268 ILE A CD1 1 ATOM 4302 N N . THR A 1 553 ? -43.207 15.054 -37.416 1.00 312.13 ? 1269 THR A N 1 ATOM 4303 C CA . THR A 1 553 ? -43.320 13.600 -37.367 1.00 314.86 ? 1269 THR A CA 1 ATOM 4304 C C . THR A 1 553 ? -42.297 13.018 -38.337 1.00 313.40 ? 1269 THR A C 1 ATOM 4305 O O . THR A 1 553 ? -42.402 13.211 -39.554 1.00 310.26 ? 1269 THR A O 1 ATOM 4306 C CB . THR A 1 553 ? -44.745 13.153 -37.700 1.00 316.22 ? 1269 THR A CB 1 ATOM 4307 O OG1 . THR A 1 553 ? -44.765 11.743 -37.959 1.00 319.80 ? 1269 THR A OG1 1 ATOM 4308 C CG2 . THR A 1 553 ? -45.290 13.912 -38.909 1.00 316.04 ? 1269 THR A CG2 1 ATOM 4309 N N . CYS A 1 554 ? -41.301 12.320 -37.800 1.00 300.50 ? 1270 CYS A N 1 ATOM 4310 C CA . CYS A 1 554 ? -40.160 11.860 -38.581 1.00 306.76 ? 1270 CYS A CA 1 ATOM 4311 C C . CYS A 1 554 ? -40.235 10.356 -38.802 1.00 307.36 ? 1270 CYS A C 1 ATOM 4312 O O . CYS A 1 554 ? -40.456 9.590 -37.857 1.00 311.48 ? 1270 CYS A O 1 ATOM 4313 C CB . CYS A 1 554 ? -38.846 12.232 -37.895 1.00 312.01 ? 1270 CYS A CB 1 ATOM 4314 S SG . CYS A 1 554 ? -38.479 14.000 -37.908 1.00 323.71 ? 1270 CYS A SG 1 ATOM 4315 N N . GLU A 1 555 ? -40.033 9.946 -40.051 1.00 310.62 ? 1271 GLU A N 1 ATOM 4316 C CA . GLU A 1 555 ? -40.096 8.557 -40.476 1.00 311.86 ? 1271 GLU A CA 1 ATOM 4317 C C . GLU A 1 555 ? -38.827 8.222 -41.245 1.00 308.19 ? 1271 GLU A C 1 ATOM 4318 O O . GLU A 1 555 ? -38.316 9.053 -42.001 1.00 313.28 ? 1271 GLU A O 1 ATOM 4319 C CB . GLU A 1 555 ? -41.337 8.317 -41.351 1.00 315.76 ? 1271 GLU A CB 1 ATOM 4320 C CG . GLU A 1 555 ? -41.354 7.002 -42.111 1.00 322.90 ? 1271 GLU A CG 1 ATOM 4321 C CD . GLU A 1 555 ? -42.477 6.940 -43.131 1.00 330.05 ? 1271 GLU A CD 1 ATOM 4322 O OE1 . GLU A 1 555 ? -43.402 7.776 -43.046 1.00 334.65 ? 1271 GLU A OE1 1 ATOM 4323 O OE2 . GLU A 1 555 ? -42.432 6.062 -44.019 1.00 335.15 ? 1271 GLU A OE2 1 ATOM 4324 N N . GLU A 1 556 ? -38.311 7.012 -41.044 1.00 308.73 ? 1272 GLU A N 1 ATOM 4325 C CA . GLU A 1 556 ? -37.111 6.566 -41.739 1.00 309.83 ? 1272 GLU A CA 1 ATOM 4326 C C . GLU A 1 556 ? -37.495 5.840 -43.022 1.00 306.50 ? 1272 GLU A C 1 ATOM 4327 O O . GLU A 1 556 ? -38.357 4.955 -43.011 1.00 306.70 ? 1272 GLU A O 1 ATOM 4328 C CB . GLU A 1 556 ? -36.267 5.657 -40.844 1.00 314.00 ? 1272 GLU A CB 1 ATOM 4329 C CG . GLU A 1 556 ? -35.029 5.096 -41.529 1.00 318.85 ? 1272 GLU A CG 1 ATOM 4330 C CD . GLU A 1 556 ? -33.995 4.579 -40.547 1.00 323.94 ? 1272 GLU A CD 1 ATOM 4331 O OE1 . GLU A 1 556 ? -33.571 5.355 -39.664 1.00 320.90 ? 1272 GLU A OE1 1 ATOM 4332 O OE2 . GLU A 1 556 ? -33.607 3.396 -40.656 1.00 329.28 ? 1272 GLU A OE2 1 ATOM 4333 N N . LYS A 1 557 ? -36.857 6.224 -44.126 1.00 313.36 ? 1273 LYS A N 1 ATOM 4334 C CA . LYS A 1 557 ? -37.066 5.607 -45.429 1.00 311.93 ? 1273 LYS A CA 1 ATOM 4335 C C . LYS A 1 557 ? -35.723 5.134 -45.975 1.00 311.69 ? 1273 LYS A C 1 ATOM 4336 O O . LYS A 1 557 ? -34.689 5.238 -45.311 1.00 309.30 ? 1273 LYS A O 1 ATOM 4337 C CB . LYS A 1 557 ? -37.747 6.577 -46.402 1.00 311.89 ? 1273 LYS A CB 1 ATOM 4338 C CG . LYS A 1 557 ? -39.211 6.842 -46.110 1.00 313.61 ? 1273 LYS A CG 1 ATOM 4339 C CD . LYS A 1 557 ? -39.833 7.687 -47.209 1.00 317.13 ? 1273 LYS A CD 1 ATOM 4340 C CE . LYS A 1 557 ? -41.333 7.823 -47.026 1.00 321.00 ? 1273 LYS A CE 1 ATOM 4341 N NZ . LYS A 1 557 ? -41.950 8.584 -48.146 1.00 324.51 ? 1273 LYS A NZ 1 ATOM 4342 N N . MET A 1 558 ? -35.739 4.614 -47.202 1.00 309.11 ? 1274 MET A N 1 ATOM 4343 C CA . MET A 1 558 ? -34.559 4.014 -47.813 1.00 313.06 ? 1274 MET A CA 1 ATOM 4344 C C . MET A 1 558 ? -34.424 4.466 -49.259 1.00 315.98 ? 1274 MET A C 1 ATOM 4345 O O . MET A 1 558 ? -35.410 4.479 -50.003 1.00 318.69 ? 1274 MET A O 1 ATOM 4346 C CB . MET A 1 558 ? -34.631 2.482 -47.756 1.00 314.59 ? 1274 MET A CB 1 ATOM 4347 C CG . MET A 1 558 ? -34.532 1.895 -46.359 1.00 317.06 ? 1274 MET A CG 1 ATOM 4348 S SD . MET A 1 558 ? -32.863 1.996 -45.687 1.00 324.60 ? 1274 MET A SD 1 ATOM 4349 C CE . MET A 1 558 ? -33.116 1.322 -44.047 1.00 325.13 ? 1274 MET A CE 1 ATOM 4350 N N . VAL A 1 559 ? -33.204 4.832 -49.651 1.00 323.02 ? 1275 VAL A N 1 ATOM 4351 C CA . VAL A 1 559 ? -32.852 5.071 -51.046 1.00 320.01 ? 1275 VAL A CA 1 ATOM 4352 C C . VAL A 1 559 ? -31.960 3.931 -51.511 1.00 317.91 ? 1275 VAL A C 1 ATOM 4353 O O . VAL A 1 559 ? -31.080 3.478 -50.770 1.00 319.48 ? 1275 VAL A O 1 ATOM 4354 C CB . VAL A 1 559 ? -32.132 6.420 -51.256 1.00 324.67 ? 1275 VAL A CB 1 ATOM 4355 C CG1 . VAL A 1 559 ? -31.928 6.690 -52.743 1.00 328.49 ? 1275 VAL A CG1 1 ATOM 4356 C CG2 . VAL A 1 559 ? -32.898 7.551 -50.621 1.00 325.54 ? 1275 VAL A CG2 1 ATOM 4357 N N . SER A 1 560 ? -32.190 3.464 -52.733 1.00 329.41 ? 1276 SER A N 1 ATOM 4358 C CA . SER A 1 560 ? -31.245 2.589 -53.410 1.00 328.08 ? 1276 SER A CA 1 ATOM 4359 C C . SER A 1 560 ? -30.349 3.449 -54.291 1.00 323.92 ? 1276 SER A C 1 ATOM 4360 O O . SER A 1 560 ? -30.842 4.277 -55.065 1.00 320.66 ? 1276 SER A O 1 ATOM 4361 C CB . SER A 1 560 ? -31.966 1.534 -54.249 1.00 329.54 ? 1276 SER A CB 1 ATOM 4362 O OG . SER A 1 560 ? -32.440 2.089 -55.463 1.00 333.23 ? 1276 SER A OG 1 ATOM 4363 N N . MET A 1 561 ? -29.040 3.266 -54.162 1.00 322.30 ? 1277 MET A N 1 ATOM 4364 C CA . MET A 1 561 ? -28.063 4.098 -54.860 1.00 321.79 ? 1277 MET A CA 1 ATOM 4365 C C . MET A 1 561 ? -27.178 3.201 -55.716 1.00 319.45 ? 1277 MET A C 1 ATOM 4366 O O . MET A 1 561 ? -26.275 2.531 -55.205 1.00 319.69 ? 1277 MET A O 1 ATOM 4367 C CB . MET A 1 561 ? -27.245 4.918 -53.872 1.00 322.92 ? 1277 MET A CB 1 ATOM 4368 C CG . MET A 1 561 ? -28.105 5.806 -53.002 1.00 323.57 ? 1277 MET A CG 1 ATOM 4369 S SD . MET A 1 561 ? -27.237 7.227 -52.328 1.00 329.40 ? 1277 MET A SD 1 ATOM 4370 C CE . MET A 1 561 ? -28.587 8.004 -51.449 1.00 335.27 ? 1277 MET A CE 1 ATOM 4371 N N . ALA A 1 562 ? -27.443 3.197 -57.017 1.00 324.21 ? 1278 ALA A N 1 ATOM 4372 C CA . ALA A 1 562 ? -26.651 2.420 -57.955 1.00 320.91 ? 1278 ALA A CA 1 ATOM 4373 C C . ALA A 1 562 ? -25.381 3.184 -58.312 1.00 319.37 ? 1278 ALA A C 1 ATOM 4374 O O . ALA A 1 562 ? -25.436 4.361 -58.686 1.00 319.41 ? 1278 ALA A O 1 ATOM 4375 C CB . ALA A 1 562 ? -27.471 2.118 -59.207 1.00 321.78 ? 1278 ALA A CB 1 ATOM 4376 N N . ARG A 1 563 ? -24.236 2.516 -58.183 1.00 321.96 ? 1279 ARG A N 1 ATOM 4377 C CA . ARG A 1 563 ? -22.942 3.124 -58.446 1.00 319.73 ? 1279 ARG A CA 1 ATOM 4378 C C . ARG A 1 563 ? -22.142 2.255 -59.403 1.00 318.59 ? 1279 ARG A C 1 ATOM 4379 O O . ARG A 1 563 ? -22.293 1.032 -59.431 1.00 314.20 ? 1279 ARG A O 1 ATOM 4380 C CB . ARG A 1 563 ? -22.130 3.313 -57.155 1.00 321.37 ? 1279 ARG A CB 1 ATOM 4381 C CG . ARG A 1 563 ? -22.833 4.094 -56.061 1.00 324.36 ? 1279 ARG A CG 1 ATOM 4382 C CD . ARG A 1 563 ? -21.930 4.239 -54.849 1.00 326.25 ? 1279 ARG A CD 1 ATOM 4383 N NE . ARG A 1 563 ? -22.647 4.762 -53.692 1.00 327.22 ? 1279 ARG A NE 1 ATOM 4384 C CZ . ARG A 1 563 ? -22.865 6.054 -53.473 1.00 325.34 ? 1279 ARG A CZ 1 ATOM 4385 N NH1 . ARG A 1 563 ? -22.423 6.957 -54.337 1.00 320.09 ? 1279 ARG A NH1 1 ATOM 4386 N NH2 . ARG A 1 563 ? -23.528 6.442 -52.392 1.00 329.71 ? 1279 ARG A NH2 1 ATOM 4387 N N . ASN A 1 564 ? -21.285 2.903 -60.184 1.00 329.39 ? 1280 ASN A N 1 ATOM 4388 C CA . ASN A 1 564 ? -20.293 2.185 -60.966 1.00 329.60 ? 1280 ASN A CA 1 ATOM 4389 C C . ASN A 1 564 ? -19.074 1.877 -60.105 1.00 332.47 ? 1280 ASN A C 1 ATOM 4390 O O . ASN A 1 564 ? -18.742 2.615 -59.173 1.00 335.82 ? 1280 ASN A O 1 ATOM 4391 C CB . ASN A 1 564 ? -19.869 2.996 -62.192 1.00 326.57 ? 1280 ASN A CB 1 ATOM 4392 C CG . ASN A 1 564 ? -20.893 2.948 -63.308 1.00 325.22 ? 1280 ASN A CG 1 ATOM 4393 O OD1 . ASN A 1 564 ? -21.738 2.054 -63.353 1.00 324.93 ? 1280 ASN A OD1 1 ATOM 4394 N ND2 . ASN A 1 564 ? -20.812 3.905 -64.225 1.00 323.34 ? 1280 ASN A ND2 1 ATOM 4395 N N . THR A 1 565 ? -18.411 0.768 -60.422 1.00 332.59 ? 1281 THR A N 1 ATOM 4396 C CA . THR A 1 565 ? -17.206 0.341 -59.719 1.00 331.09 ? 1281 THR A CA 1 ATOM 4397 C C . THR A 1 565 ? -16.096 0.172 -60.748 1.00 329.11 ? 1281 THR A C 1 ATOM 4398 O O . THR A 1 565 ? -16.131 -0.761 -61.557 1.00 330.72 ? 1281 THR A O 1 ATOM 4399 C CB . THR A 1 565 ? -17.443 -0.957 -58.945 1.00 332.49 ? 1281 THR A CB 1 ATOM 4400 O OG1 . THR A 1 565 ? -18.563 -0.791 -58.065 1.00 333.44 ? 1281 THR A OG1 1 ATOM 4401 C CG2 . THR A 1 565 ? -16.216 -1.319 -58.124 1.00 334.76 ? 1281 THR A CG2 1 ATOM 4402 N N . TYR A 1 566 ? -15.118 1.070 -60.714 1.00 341.19 ? 1282 TYR A N 1 ATOM 4403 C CA . TYR A 1 566 ? -14.049 1.119 -61.699 1.00 338.70 ? 1282 TYR A CA 1 ATOM 4404 C C . TYR A 1 566 ? -12.796 0.438 -61.164 1.00 336.86 ? 1282 TYR A C 1 ATOM 4405 O O . TYR A 1 566 ? -12.552 0.407 -59.955 1.00 341.49 ? 1282 TYR A O 1 ATOM 4406 C CB . TYR A 1 566 ? -13.730 2.569 -62.078 1.00 339.07 ? 1282 TYR A CB 1 ATOM 4407 C CG . TYR A 1 566 ? -14.952 3.429 -62.327 1.00 342.20 ? 1282 TYR A CG 1 ATOM 4408 C CD1 . TYR A 1 566 ? -15.485 3.562 -63.604 1.00 345.82 ? 1282 TYR A CD1 1 ATOM 4409 C CD2 . TYR A 1 566 ? -15.570 4.111 -61.285 1.00 343.23 ? 1282 TYR A CD2 1 ATOM 4410 C CE1 . TYR A 1 566 ? -16.601 4.349 -63.834 1.00 347.07 ? 1282 TYR A CE1 1 ATOM 4411 C CE2 . TYR A 1 566 ? -16.687 4.898 -61.506 1.00 345.46 ? 1282 TYR A CE2 1 ATOM 4412 C CZ . TYR A 1 566 ? -17.197 5.015 -62.782 1.00 347.31 ? 1282 TYR A CZ 1 ATOM 4413 O OH . TYR A 1 566 ? -18.306 5.796 -63.010 1.00 350.83 ? 1282 TYR A OH 1 ATOM 4414 N N . GLY A 1 567 ? -12.002 -0.107 -62.076 1.00 361.93 ? 1283 GLY A N 1 ATOM 4415 C CA . GLY A 1 567 ? -10.761 -0.744 -61.686 1.00 364.88 ? 1283 GLY A CA 1 ATOM 4416 C C . GLY A 1 567 ? -10.088 -1.393 -62.876 1.00 367.98 ? 1283 GLY A C 1 ATOM 4417 O O . GLY A 1 567 ? -10.689 -1.570 -63.942 1.00 366.63 ? 1283 GLY A O 1 ATOM 4418 N N . GLU A 1 568 ? -8.819 -1.740 -62.672 1.00 373.19 ? 1284 GLU A N 1 ATOM 4419 C CA . GLU A 1 568 ? -8.022 -2.449 -63.662 1.00 380.09 ? 1284 GLU A CA 1 ATOM 4420 C C . GLU A 1 568 ? -8.121 -3.965 -63.521 1.00 381.65 ? 1284 GLU A C 1 ATOM 4421 O O . GLU A 1 568 ? -7.548 -4.687 -64.343 1.00 385.91 ? 1284 GLU A O 1 ATOM 4422 C CB . GLU A 1 568 ? -6.557 -2.006 -63.567 1.00 387.48 ? 1284 GLU A CB 1 ATOM 4423 C CG . GLU A 1 568 ? -6.342 -0.511 -63.794 1.00 395.33 ? 1284 GLU A CG 1 ATOM 4424 C CD . GLU A 1 568 ? -6.563 -0.098 -65.238 1.00 400.02 ? 1284 GLU A CD 1 ATOM 4425 O OE1 . GLU A 1 568 ? -5.766 -0.518 -66.105 1.00 405.26 ? 1284 GLU A OE1 1 ATOM 4426 O OE2 . GLU A 1 568 ? -7.536 0.637 -65.507 1.00 399.17 ? 1284 GLU A OE2 1 ATOM 4427 N N . SER A 1 569 ? -8.828 -4.457 -62.504 1.00 381.68 ? 1285 SER A N 1 ATOM 4428 C CA . SER A 1 569 ? -9.054 -5.886 -62.324 1.00 383.86 ? 1285 SER A CA 1 ATOM 4429 C C . SER A 1 569 ? -10.224 -6.080 -61.369 1.00 387.55 ? 1285 SER A C 1 ATOM 4430 O O . SER A 1 569 ? -10.524 -5.217 -60.542 1.00 398.22 ? 1285 SER A O 1 ATOM 4431 C CB . SER A 1 569 ? -7.799 -6.600 -61.808 1.00 383.01 ? 1285 SER A CB 1 ATOM 4432 O OG . SER A 1 569 ? -7.073 -5.781 -60.908 1.00 384.76 ? 1285 SER A OG 1 ATOM 4433 N N . LYS A 1 570 ? -10.883 -7.236 -61.493 1.00 380.02 ? 1286 LYS A N 1 ATOM 4434 C CA . LYS A 1 570 ? -12.130 -7.462 -60.770 1.00 385.65 ? 1286 LYS A CA 1 ATOM 4435 C C . LYS A 1 570 ? -11.919 -7.704 -59.282 1.00 392.13 ? 1286 LYS A C 1 ATOM 4436 O O . LYS A 1 570 ? -12.864 -7.532 -58.503 1.00 391.54 ? 1286 LYS A O 1 ATOM 4437 C CB . LYS A 1 570 ? -12.891 -8.642 -61.376 1.00 385.90 ? 1286 LYS A CB 1 ATOM 4438 C CG . LYS A 1 570 ? -13.437 -8.386 -62.767 1.00 383.54 ? 1286 LYS A CG 1 ATOM 4439 C CD . LYS A 1 570 ? -14.111 -9.632 -63.314 1.00 382.99 ? 1286 LYS A CD 1 ATOM 4440 C CE . LYS A 1 570 ? -14.648 -9.401 -64.714 1.00 382.66 ? 1286 LYS A CE 1 ATOM 4441 N NZ . LYS A 1 570 ? -15.191 -10.654 -65.308 1.00 384.00 ? 1286 LYS A NZ 1 ATOM 4442 N N . GLY A 1 571 ? -10.721 -8.109 -58.869 1.00 389.97 ? 1287 GLY A N 1 ATOM 4443 C CA . GLY A 1 571 ? -10.436 -8.263 -57.457 1.00 392.40 ? 1287 GLY A CA 1 ATOM 4444 C C . GLY A 1 571 ? -10.478 -6.924 -56.753 1.00 396.49 ? 1287 GLY A C 1 ATOM 4445 O O . GLY A 1 571 ? -9.432 -6.339 -56.456 1.00 394.14 ? 1287 GLY A O 1 ATOM 4446 N N . ARG A 1 572 ? -11.690 -6.441 -56.481 1.00 387.87 ? 1288 ARG A N 1 ATOM 4447 C CA . ARG A 1 572 ? -11.932 -5.066 -56.044 1.00 385.82 ? 1288 ARG A CA 1 ATOM 4448 C C . ARG A 1 572 ? -11.363 -4.073 -57.053 1.00 383.29 ? 1288 ARG A C 1 ATOM 4449 O O . ARG A 1 572 ? -12.105 -3.306 -57.668 1.00 373.67 ? 1288 ARG A O 1 ATOM 4450 C CB . ARG A 1 572 ? -11.336 -4.804 -54.658 1.00 383.60 ? 1288 ARG A CB 1 ATOM 4451 C CG . ARG A 1 572 ? -11.912 -5.664 -53.549 1.00 381.85 ? 1288 ARG A CG 1 ATOM 4452 C CD . ARG A 1 572 ? -13.426 -5.602 -53.526 1.00 382.23 ? 1288 ARG A CD 1 ATOM 4453 N NE . ARG A 1 572 ? -13.964 -5.977 -52.222 1.00 383.80 ? 1288 ARG A NE 1 ATOM 4454 C CZ . ARG A 1 572 ? -15.234 -6.297 -52.003 1.00 381.35 ? 1288 ARG A CZ 1 ATOM 4455 N NH1 . ARG A 1 572 ? -16.100 -6.299 -53.008 1.00 377.22 ? 1288 ARG A NH1 1 ATOM 4456 N NH2 . ARG A 1 572 ? -15.639 -6.621 -50.783 1.00 381.39 ? 1288 ARG A NH2 1 HETATM 4457 C C1 . NAG B 2 . ? -19.214 29.638 -20.629 0.00 335.51 ? 1300 NAG A C1 1 HETATM 4458 C C2 . NAG B 2 . ? -20.250 28.547 -20.906 0.00 333.60 ? 1300 NAG A C2 1 HETATM 4459 C C3 . NAG B 2 . ? -21.628 29.146 -21.025 0.00 333.32 ? 1300 NAG A C3 1 HETATM 4460 C C4 . NAG B 2 . ? -22.064 29.621 -19.654 0.00 334.06 ? 1300 NAG A C4 1 HETATM 4461 C C5 . NAG B 2 . ? -21.113 30.695 -19.126 0.00 334.03 ? 1300 NAG A C5 1 HETATM 4462 C C6 . NAG B 2 . ? -20.868 30.588 -17.637 0.00 330.63 ? 1300 NAG A C6 1 HETATM 4463 C C7 . NAG B 2 . ? -19.418 26.571 -22.116 0.00 330.79 ? 1300 NAG A C7 1 HETATM 4464 C C8 . NAG B 2 . ? -19.240 25.927 -20.771 0.00 332.42 ? 1300 NAG A C8 1 HETATM 4465 N N2 . NAG B 2 . ? -19.908 27.818 -22.117 0.00 330.35 ? 1300 NAG A N2 1 HETATM 4466 O O3 . NAG B 2 . ? -22.534 28.154 -21.501 0.00 332.80 ? 1300 NAG A O3 1 HETATM 4467 O O4 . NAG B 2 . ? -23.375 30.175 -19.721 0.00 333.54 ? 1300 NAG A O4 1 HETATM 4468 O O5 . NAG B 2 . ? -19.815 30.737 -19.762 0.00 334.75 ? 1300 NAG A O5 1 HETATM 4469 O O6 . NAG B 2 . ? -22.084 30.607 -16.899 0.00 331.15 ? 1300 NAG A O6 1 HETATM 4470 O O7 . NAG B 2 . ? -19.133 25.986 -23.155 0.00 333.53 ? 1300 NAG A O7 1 HETATM 4471 C C1 . NAG C 2 . ? -24.401 29.286 -19.243 0.00 333.65 ? 1301 NAG A C1 1 HETATM 4472 C C2 . NAG C 2 . ? -25.596 30.136 -18.804 0.00 332.21 ? 1301 NAG A C2 1 HETATM 4473 C C3 . NAG C 2 . ? -26.802 29.264 -18.444 0.00 333.64 ? 1301 NAG A C3 1 HETATM 4474 C C4 . NAG C 2 . ? -27.089 28.237 -19.530 0.00 336.68 ? 1301 NAG A C4 1 HETATM 4475 C C5 . NAG C 2 . ? -25.816 27.457 -19.834 0.00 338.51 ? 1301 NAG A C5 1 HETATM 4476 C C6 . NAG C 2 . ? -25.971 26.444 -20.946 0.00 339.41 ? 1301 NAG A C6 1 HETATM 4477 C C7 . NAG C 2 . ? -24.909 32.265 -17.787 0.00 331.06 ? 1301 NAG A C7 1 HETATM 4478 C C8 . NAG C 2 . ? -24.554 32.961 -16.507 0.00 331.81 ? 1301 NAG A C8 1 HETATM 4479 N N2 . NAG C 2 . ? -25.236 30.975 -17.675 0.00 330.73 ? 1301 NAG A N2 1 HETATM 4480 O O3 . NAG C 2 . ? -27.940 30.099 -18.251 0.00 335.00 ? 1301 NAG A O3 1 HETATM 4481 O O4 . NAG C 2 . ? -28.104 27.344 -19.080 0.00 339.45 ? 1301 NAG A O4 1 HETATM 4482 O O5 . NAG C 2 . ? -24.795 28.372 -20.247 0.00 336.46 ? 1301 NAG A O5 1 HETATM 4483 O O6 . NAG C 2 . ? -26.471 27.042 -22.134 0.00 341.43 ? 1301 NAG A O6 1 HETATM 4484 O O7 . NAG C 2 . ? -24.903 32.845 -18.868 0.00 331.34 ? 1301 NAG A O7 1 HETATM 4485 C C1 . BMA D 3 . ? -29.224 27.347 -19.994 0.00 339.53 ? 1302 BMA A C1 1 HETATM 4486 C C2 . BMA D 3 . ? -30.001 26.043 -19.748 0.00 340.24 ? 1302 BMA A C2 1 HETATM 4487 C C3 . BMA D 3 . ? -31.247 26.011 -20.624 0.00 341.31 ? 1302 BMA A C3 1 HETATM 4488 C C4 . BMA D 3 . ? -32.068 27.300 -20.494 0.00 338.02 ? 1302 BMA A C4 1 HETATM 4489 C C5 . BMA D 3 . ? -31.177 28.538 -20.711 0.00 340.02 ? 1302 BMA A C5 1 HETATM 4490 C C6 . BMA D 3 . ? -31.922 29.821 -20.435 0.00 343.55 ? 1302 BMA A C6 1 HETATM 4491 O O2 . BMA D 3 . ? -30.447 25.972 -18.400 0.00 340.96 ? 1302 BMA A O2 1 HETATM 4492 O O3 . BMA D 3 . ? -32.063 24.890 -20.305 0.00 348.93 ? 1302 BMA A O3 1 HETATM 4493 O O4 . BMA D 3 . ? -33.122 27.298 -21.448 0.00 336.87 ? 1302 BMA A O4 1 HETATM 4494 O O5 . BMA D 3 . ? -30.067 28.476 -19.799 0.00 338.66 ? 1302 BMA A O5 1 HETATM 4495 O O6 . BMA D 3 . ? -32.645 29.628 -19.223 0.00 349.82 ? 1302 BMA A O6 1 HETATM 4496 C C1 . MAN E 4 . ? -33.254 30.866 -18.799 0.00 342.02 ? 1303 MAN A C1 1 HETATM 4497 C C2 . MAN E 4 . ? -33.559 30.745 -17.303 0.00 344.94 ? 1303 MAN A C2 1 HETATM 4498 C C3 . MAN E 4 . ? -34.551 29.604 -17.045 0.00 348.22 ? 1303 MAN A C3 1 HETATM 4499 C C4 . MAN E 4 . ? -35.719 29.537 -18.071 0.00 345.75 ? 1303 MAN A C4 1 HETATM 4500 C C5 . MAN E 4 . ? -35.326 29.959 -19.508 0.00 346.53 ? 1303 MAN A C5 1 HETATM 4501 C C6 . MAN E 4 . ? -36.517 30.380 -20.323 0.00 349.71 ? 1303 MAN A C6 1 HETATM 4502 O O2 . MAN E 4 . ? -34.194 31.928 -16.816 0.00 344.26 ? 1303 MAN A O2 1 HETATM 4503 O O3 . MAN E 4 . ? -35.111 29.701 -15.735 0.00 359.43 ? 1303 MAN A O3 1 HETATM 4504 O O4 . MAN E 4 . ? -36.224 28.202 -18.114 0.00 341.88 ? 1303 MAN A O4 1 HETATM 4505 O O5 . MAN E 4 . ? -34.438 31.084 -19.495 0.00 345.15 ? 1303 MAN A O5 1 HETATM 4506 O O6 . MAN E 4 . ? -37.682 29.992 -19.634 0.00 354.42 ? 1303 MAN A O6 1 HETATM 4507 C C1 . MAN F 4 . ? -34.251 29.075 -14.767 0.00 350.56 ? 1304 MAN A C1 1 HETATM 4508 C C2 . MAN F 4 . ? -35.087 28.044 -13.982 0.00 353.69 ? 1304 MAN A C2 1 HETATM 4509 C C3 . MAN F 4 . ? -36.112 28.762 -13.093 0.00 354.44 ? 1304 MAN A C3 1 HETATM 4510 C C4 . MAN F 4 . ? -35.464 29.866 -12.239 0.00 354.74 ? 1304 MAN A C4 1 HETATM 4511 C C5 . MAN F 4 . ? -34.609 30.807 -13.105 0.00 355.03 ? 1304 MAN A C5 1 HETATM 4512 C C6 . MAN F 4 . ? -33.796 31.777 -12.260 0.00 353.39 ? 1304 MAN A C6 1 HETATM 4513 O O2 . MAN F 4 . ? -34.234 27.265 -13.122 0.00 354.78 ? 1304 MAN A O2 1 HETATM 4514 O O3 . MAN F 4 . ? -36.829 27.853 -12.257 0.00 350.48 ? 1304 MAN A O3 1 HETATM 4515 O O4 . MAN F 4 . ? -36.480 30.627 -11.590 0.00 352.38 ? 1304 MAN A O4 1 HETATM 4516 O O5 . MAN F 4 . ? -33.675 30.037 -13.904 0.00 353.73 ? 1304 MAN A O5 1 HETATM 4517 O O6 . MAN F 4 . ? -32.841 32.421 -13.098 0.00 351.46 ? 1304 MAN A O6 1 HETATM 4518 C C1 . MAN G 4 . ? -34.510 25.838 -13.170 0.00 350.36 ? 1305 MAN A C1 1 HETATM 4519 C C2 . MAN G 4 . ? -33.202 25.121 -12.732 0.00 352.12 ? 1305 MAN A C2 1 HETATM 4520 C C3 . MAN G 4 . ? -32.159 25.199 -13.838 0.00 352.51 ? 1305 MAN A C3 1 HETATM 4521 C C4 . MAN G 4 . ? -32.686 24.598 -15.142 0.00 354.95 ? 1305 MAN A C4 1 HETATM 4522 C C5 . MAN G 4 . ? -33.993 25.280 -15.566 0.00 356.41 ? 1305 MAN A C5 1 HETATM 4523 C C6 . MAN G 4 . ? -34.693 24.559 -16.704 0.00 358.97 ? 1305 MAN A C6 1 HETATM 4524 O O2 . MAN G 4 . ? -33.425 23.730 -12.506 0.00 356.31 ? 1305 MAN A O2 1 HETATM 4525 O O3 . MAN G 4 . ? -30.954 24.542 -13.462 0.00 347.51 ? 1305 MAN A O3 1 HETATM 4526 O O4 . MAN G 4 . ? -31.724 24.798 -16.170 0.00 356.02 ? 1305 MAN A O4 1 HETATM 4527 O O5 . MAN G 4 . ? -34.957 25.366 -14.458 0.00 351.52 ? 1305 MAN A O5 1 HETATM 4528 O O6 . MAN G 4 . ? -35.139 23.296 -16.219 0.00 360.94 ? 1305 MAN A O6 1 HETATM 4529 C C1 . MAN H 4 . ? -38.769 30.175 -20.564 0.00 345.66 ? 1306 MAN A C1 1 HETATM 4530 C C2 . MAN H 4 . ? -39.094 31.697 -20.656 0.00 352.50 ? 1306 MAN A C2 1 HETATM 4531 C C3 . MAN H 4 . ? -39.850 32.176 -19.325 0.00 351.08 ? 1306 MAN A C3 1 HETATM 4532 C C4 . MAN H 4 . ? -40.800 31.121 -18.654 0.00 346.54 ? 1306 MAN A C4 1 HETATM 4533 C C5 . MAN H 4 . ? -40.306 29.683 -18.794 0.00 343.38 ? 1306 MAN A C5 1 HETATM 4534 C C6 . MAN H 4 . ? -41.398 28.673 -18.466 0.00 343.65 ? 1306 MAN A C6 1 HETATM 4535 O O2 . MAN H 4 . ? -39.824 31.860 -21.917 0.00 363.56 ? 1306 MAN A O2 1 HETATM 4536 O O3 . MAN H 4 . ? -40.523 33.454 -19.403 0.00 354.85 ? 1306 MAN A O3 1 HETATM 4537 O O4 . MAN H 4 . ? -40.909 31.411 -17.260 0.00 341.84 ? 1306 MAN A O4 1 HETATM 4538 O O5 . MAN H 4 . ? -39.911 29.450 -20.146 0.00 341.05 ? 1306 MAN A O5 1 HETATM 4539 O O6 . MAN H 4 . ? -40.864 27.674 -17.602 0.00 340.81 ? 1306 MAN A O6 1 HETATM 4540 C C1 . MAN I 4 . ? -40.545 33.027 -22.355 0.00 352.70 ? 1307 MAN A C1 1 HETATM 4541 C C2 . MAN I 4 . ? -40.160 33.159 -23.812 0.00 353.90 ? 1307 MAN A C2 1 HETATM 4542 C C3 . MAN I 4 . ? -41.235 33.986 -24.455 0.00 356.36 ? 1307 MAN A C3 1 HETATM 4543 C C4 . MAN I 4 . ? -41.341 35.394 -23.761 0.00 356.43 ? 1307 MAN A C4 1 HETATM 4544 C C5 . MAN I 4 . ? -41.148 35.346 -22.181 0.00 354.32 ? 1307 MAN A C5 1 HETATM 4545 C C6 . MAN I 4 . ? -42.454 35.198 -21.454 0.00 352.63 ? 1307 MAN A C6 1 HETATM 4546 O O2 . MAN I 4 . ? -40.166 31.920 -24.470 0.00 349.46 ? 1307 MAN A O2 1 HETATM 4547 O O3 . MAN I 4 . ? -42.477 33.323 -24.407 0.00 360.00 ? 1307 MAN A O3 1 HETATM 4548 O O4 . MAN I 4 . ? -40.399 36.308 -24.349 0.00 357.00 ? 1307 MAN A O4 1 HETATM 4549 O O5 . MAN I 4 . ? -40.254 34.243 -21.732 0.00 353.18 ? 1307 MAN A O5 1 HETATM 4550 O O6 . MAN I 4 . ? -42.254 35.433 -20.070 0.00 353.31 ? 1307 MAN A O6 1 HETATM 4551 C C1 . MAN J 4 . ? -32.122 24.007 -21.444 0.00 338.73 ? 1308 MAN A C1 1 HETATM 4552 C C2 . MAN J 4 . ? -33.298 23.032 -21.208 0.00 344.77 ? 1308 MAN A C2 1 HETATM 4553 C C3 . MAN J 4 . ? -32.964 22.065 -20.069 0.00 347.12 ? 1308 MAN A C3 1 HETATM 4554 C C4 . MAN J 4 . ? -31.587 21.403 -20.263 0.00 347.46 ? 1308 MAN A C4 1 HETATM 4555 C C5 . MAN J 4 . ? -30.508 22.468 -20.493 0.00 345.65 ? 1308 MAN A C5 1 HETATM 4556 C C6 . MAN J 4 . ? -29.156 21.865 -20.837 0.00 347.17 ? 1308 MAN A C6 1 HETATM 4557 O O2 . MAN J 4 . ? -33.528 22.221 -22.362 0.00 352.67 ? 1308 MAN A O2 1 HETATM 4558 O O3 . MAN J 4 . ? -33.968 21.063 -19.922 0.00 348.25 ? 1308 MAN A O3 1 HETATM 4559 O O4 . MAN J 4 . ? -31.252 20.642 -19.107 0.00 350.34 ? 1308 MAN A O4 1 HETATM 4560 O O5 . MAN J 4 . ? -30.896 23.312 -21.599 0.00 341.11 ? 1308 MAN A O5 1 HETATM 4561 O O6 . MAN J 4 . ? -28.165 22.481 -20.019 0.00 351.42 ? 1308 MAN A O6 1 HETATM 4562 C C1 . MAN K 4 . ? -34.847 22.479 -22.887 0.00 341.11 ? 1309 MAN A C1 1 HETATM 4563 C C2 . MAN K 4 . ? -35.152 21.354 -23.890 0.00 342.87 ? 1309 MAN A C2 1 HETATM 4564 C C3 . MAN K 4 . ? -34.224 21.478 -25.096 0.00 346.14 ? 1309 MAN A C3 1 HETATM 4565 C C4 . MAN K 4 . ? -34.304 22.886 -25.713 0.00 348.90 ? 1309 MAN A C4 1 HETATM 4566 C C5 . MAN K 4 . ? -34.045 23.957 -24.645 0.00 350.08 ? 1309 MAN A C5 1 HETATM 4567 C C6 . MAN K 4 . ? -34.291 25.361 -25.167 0.00 352.02 ? 1309 MAN A C6 1 HETATM 4568 O O2 . MAN K 4 . ? -36.476 21.473 -24.408 0.00 338.28 ? 1309 MAN A O2 1 HETATM 4569 O O3 . MAN K 4 . ? -34.516 20.492 -26.083 0.00 348.29 ? 1309 MAN A O3 1 HETATM 4570 O O4 . MAN K 4 . ? -33.331 23.025 -26.737 0.00 347.74 ? 1309 MAN A O4 1 HETATM 4571 O O5 . MAN K 4 . ? -34.921 23.752 -23.507 0.00 347.58 ? 1309 MAN A O5 1 HETATM 4572 O O6 . MAN K 4 . ? -35.517 25.354 -25.890 0.00 354.94 ? 1309 MAN A O6 1 HETATM 4573 C C1 . NAG L 2 . ? 2.784 39.224 -8.672 0.00 359.10 ? 1310 NAG A C1 1 HETATM 4574 C C2 . NAG L 2 . ? 1.543 40.094 -8.898 0.00 362.65 ? 1310 NAG A C2 1 HETATM 4575 C C3 . NAG L 2 . ? 1.389 41.112 -7.773 0.00 364.72 ? 1310 NAG A C3 1 HETATM 4576 C C4 . NAG L 2 . ? 1.361 40.406 -6.425 0.00 366.12 ? 1310 NAG A C4 1 HETATM 4577 C C5 . NAG L 2 . ? 2.631 39.584 -6.262 0.00 364.63 ? 1310 NAG A C5 1 HETATM 4578 C C6 . NAG L 2 . ? 2.644 38.773 -4.986 0.00 363.98 ? 1310 NAG A C6 1 HETATM 4579 C C7 . NAG L 2 . ? 0.512 40.953 -10.949 0.00 360.45 ? 1310 NAG A C7 1 HETATM 4580 C C8 . NAG L 2 . ? 0.736 41.671 -12.245 0.00 359.54 ? 1310 NAG A C8 1 HETATM 4581 N N2 . NAG L 2 . ? 1.595 40.764 -10.186 0.00 362.64 ? 1310 NAG A N2 1 HETATM 4582 O O3 . NAG L 2 . ? 0.183 41.846 -7.961 0.00 367.32 ? 1310 NAG A O3 1 HETATM 4583 O O4 . NAG L 2 . ? 1.266 41.355 -5.368 0.00 371.87 ? 1310 NAG A O4 1 HETATM 4584 O O5 . NAG L 2 . ? 2.745 38.650 -7.344 0.00 361.47 ? 1310 NAG A O5 1 HETATM 4585 O O6 . NAG L 2 . ? 3.951 38.685 -4.436 0.00 360.57 ? 1310 NAG A O6 1 HETATM 4586 O O7 . NAG L 2 . ? -0.599 40.560 -10.608 0.00 357.77 ? 1310 NAG A O7 1 HETATM 4587 C C1 . I3P M 5 . ? -44.789 37.686 -29.123 0.00 346.47 ? 1311 I3P A C1 1 HETATM 4588 C C2 . I3P M 5 . ? -44.950 39.033 -29.830 0.00 341.76 ? 1311 I3P A C2 1 HETATM 4589 C C3 . I3P M 5 . ? -43.857 40.025 -29.421 0.00 342.42 ? 1311 I3P A C3 1 HETATM 4590 C C4 . I3P M 5 . ? -42.454 39.447 -29.658 0.00 349.83 ? 1311 I3P A C4 1 HETATM 4591 C C5 . I3P M 5 . ? -42.302 38.103 -28.941 0.00 353.11 ? 1311 I3P A C5 1 HETATM 4592 C C6 . I3P M 5 . ? -43.386 37.106 -29.358 0.00 349.80 ? 1311 I3P A C6 1 HETATM 4593 O O1 . I3P M 5 . ? -45.769 36.814 -29.635 0.00 347.68 ? 1311 I3P A O1 1 HETATM 4594 O O2 . I3P M 5 . ? -44.856 38.813 -31.216 0.00 340.72 ? 1311 I3P A O2 1 HETATM 4595 O O3 . I3P M 5 . ? -44.038 41.192 -30.184 0.00 332.21 ? 1311 I3P A O3 1 HETATM 4596 O O4 . I3P M 5 . ? -41.475 40.322 -29.149 0.00 357.89 ? 1311 I3P A O4 1 HETATM 4597 O O5 . I3P M 5 . ? -41.035 37.557 -29.216 0.00 358.53 ? 1311 I3P A O5 1 HETATM 4598 O O6 . I3P M 5 . ? -43.199 35.938 -28.597 0.00 348.79 ? 1311 I3P A O6 1 HETATM 4599 P P1 . I3P M 5 . ? -46.161 35.466 -28.777 0.00 350.30 ? 1311 I3P A P1 1 HETATM 4600 O O11 . I3P M 5 . ? -45.607 34.254 -29.484 0.00 350.57 ? 1311 I3P A O11 1 HETATM 4601 O O12 . I3P M 5 . ? -47.661 35.336 -28.656 0.00 348.86 ? 1311 I3P A O12 1 HETATM 4602 O O13 . I3P M 5 . ? -45.553 35.545 -27.398 0.00 353.44 ? 1311 I3P A O13 1 HETATM 4603 P P4 . I3P M 5 . ? -41.028 41.644 -30.021 0.00 360.68 ? 1311 I3P A P4 1 HETATM 4604 O O41 . I3P M 5 . ? -41.985 41.873 -31.162 0.00 356.26 ? 1311 I3P A O41 1 HETATM 4605 O O42 . I3P M 5 . ? -41.058 42.845 -29.109 0.00 359.47 ? 1311 I3P A O42 1 HETATM 4606 O O43 . I3P M 5 . ? -39.643 41.456 -30.592 0.00 361.62 ? 1311 I3P A O43 1 HETATM 4607 P P5 . I3P M 5 . ? -39.989 37.426 -27.955 0.00 362.34 ? 1311 I3P A P5 1 HETATM 4608 O O51 . I3P M 5 . ? -39.014 36.306 -28.223 0.00 360.86 ? 1311 I3P A O51 1 HETATM 4609 O O52 . I3P M 5 . ? -39.234 38.722 -27.782 0.00 355.14 ? 1311 I3P A O52 1 HETATM 4610 O O53 . I3P M 5 . ? -40.761 37.130 -26.692 0.00 361.88 ? 1311 I3P A O53 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 LYS 1 717 717 LYS LYS A . n A 1 2 PHE 2 718 718 PHE PHE A . n A 1 3 ASN 3 719 719 ASN ASN A . n A 1 4 ASP 4 720 720 ASP ASP A . n A 1 5 THR 5 721 721 THR THR A . n A 1 6 LEU 6 722 722 LEU LEU A . n A 1 7 PHE 7 723 723 PHE PHE A . n A 1 8 GLY 8 724 724 GLY GLY A . n A 1 9 GLU 9 725 725 GLU GLU A . n A 1 10 MET 10 726 726 MET MET A . n A 1 11 LEU 11 727 727 LEU LEU A . n A 1 12 HIS 12 728 728 HIS HIS A . n A 1 13 GLY 13 729 729 GLY GLY A . n A 1 14 TYR 14 730 730 TYR TYR A . n A 1 15 ASN 15 731 731 ASN ASN A . n A 1 16 ASN 16 732 732 ASN ASN A . n A 1 17 ARG 17 733 733 ARG ARG A . n A 1 18 THR 18 734 734 THR THR A . n A 1 19 GLN 19 735 735 GLN GLN A . n A 1 20 HIS 20 736 736 HIS HIS A . n A 1 21 VAL 21 737 737 VAL VAL A . n A 1 22 ASN 22 738 738 ASN ASN A . n A 1 23 GLN 23 739 739 GLN GLN A . n A 1 24 GLY 24 740 740 GLY GLY A . n A 1 25 GLN 25 741 741 GLN GLN A . n A 1 26 VAL 26 742 742 VAL VAL A . n A 1 27 PHE 27 743 743 PHE PHE A . n A 1 28 GLN 28 744 744 GLN GLN A . n A 1 29 MET 29 745 745 MET MET A . n A 1 30 THR 30 746 746 THR THR A . n A 1 31 PHE 31 747 747 PHE PHE A . n A 1 32 ARG 32 748 748 ARG ARG A . n A 1 33 GLU 33 749 749 GLU GLU A . n A 1 34 ASN 34 750 750 ASN ASN A . n A 1 35 ASN 35 751 751 ASN ASN A . n A 1 36 PHE 36 752 752 PHE PHE A . n A 1 37 ILE 37 753 753 ILE ILE A . n A 1 38 LYS 38 754 754 LYS LYS A . n A 1 39 ASP 39 755 755 ASP ASP A . n A 1 40 PHE 40 756 756 PHE PHE A . n A 1 41 PRO 41 757 757 PRO PRO A . n A 1 42 GLN 42 758 758 GLN GLN A . n A 1 43 LEU 43 759 759 LEU LEU A . n A 1 44 ALA 44 760 760 ALA ALA A . n A 1 45 ASP 45 761 761 ASP ASP A . n A 1 46 GLY 46 762 762 GLY GLY A . n A 1 47 LEU 47 763 763 LEU LEU A . n A 1 48 LEU 48 764 764 LEU LEU A . n A 1 49 VAL 49 765 765 VAL VAL A . n A 1 50 ILE 50 766 766 ILE ILE A . n A 1 51 PRO 51 767 767 PRO PRO A . n A 1 52 LEU 52 768 768 LEU LEU A . n A 1 53 PRO 53 769 769 PRO PRO A . n A 1 54 VAL 54 770 770 VAL VAL A . n A 1 55 GLU 55 771 771 GLU GLU A . n A 1 56 GLU 56 772 772 GLU GLU A . n A 1 57 GLN 57 773 773 GLN GLN A . n A 1 58 CYS 58 774 774 CYS CYS A . n A 1 59 ARG 59 775 775 ARG ARG A . n A 1 60 GLY 60 776 776 GLY GLY A . n A 1 61 VAL 61 777 777 VAL VAL A . n A 1 62 LEU 62 778 778 LEU LEU A . n A 1 63 SER 63 779 779 SER SER A . n A 1 64 GLU 64 780 780 GLU GLU A . n A 1 65 PRO 65 781 781 PRO PRO A . n A 1 66 LEU 66 782 782 LEU LEU A . n A 1 67 PRO 67 783 783 PRO PRO A . n A 1 68 ASP 68 784 784 ASP ASP A . n A 1 69 LEU 69 785 785 LEU LEU A . n A 1 70 GLN 70 786 786 GLN GLN A . n A 1 71 LEU 71 787 787 LEU LEU A . n A 1 72 LEU 72 788 788 LEU LEU A . n A 1 73 THR 73 789 789 THR THR A . n A 1 74 GLY 74 790 790 GLY GLY A . n A 1 75 ASP 75 791 791 ASP ASP A . n A 1 76 ILE 76 792 792 ILE ILE A . n A 1 77 ARG 77 793 793 ARG ARG A . n A 1 78 TYR 78 794 794 TYR TYR A . n A 1 79 ASP 79 795 795 ASP ASP A . n A 1 80 GLU 80 796 796 GLU GLU A . n A 1 81 ALA 81 797 797 ALA ALA A . n A 1 82 MET 82 798 798 MET MET A . n A 1 83 GLY 83 799 799 GLY GLY A . n A 1 84 TYR 84 800 800 TYR TYR A . n A 1 85 PRO 85 801 801 PRO PRO A . n A 1 86 MET 86 802 802 MET MET A . n A 1 87 VAL 87 803 803 VAL VAL A . n A 1 88 GLN 88 804 804 GLN GLN A . n A 1 89 GLN 89 805 805 GLN GLN A . n A 1 90 TRP 90 806 806 TRP TRP A . n A 1 91 ARG 91 807 807 ARG ARG A . n A 1 92 VAL 92 808 808 VAL VAL A . n A 1 93 ARG 93 809 809 ARG ARG A . n A 1 94 SER 94 810 810 SER SER A . n A 1 95 ASN 95 811 811 ASN ASN A . n A 1 96 LEU 96 812 812 LEU LEU A . n A 1 97 TYR 97 813 813 TYR TYR A . n A 1 98 ARG 98 814 814 ARG ARG A . n A 1 99 VAL 99 815 815 VAL VAL A . n A 1 100 LYS 100 816 816 LYS LYS A . n A 1 101 LEU 101 817 817 LEU LEU A . n A 1 102 SER 102 818 818 SER SER A . n A 1 103 THR 103 819 819 THR THR A . n A 1 104 ILE 104 820 820 ILE ILE A . n A 1 105 THR 105 821 821 THR THR A . n A 1 106 LEU 106 822 822 LEU LEU A . n A 1 107 ALA 107 823 823 ALA ALA A . n A 1 108 ALA 108 824 824 ALA ALA A . n A 1 109 GLY 109 825 825 GLY GLY A . n A 1 110 PHE 110 826 826 PHE PHE A . n A 1 111 THR 111 827 827 THR THR A . n A 1 112 ASN 112 828 828 ASN ASN A . n A 1 113 VAL 113 829 829 VAL VAL A . n A 1 114 LEU 114 830 830 LEU LEU A . n A 1 115 LYS 115 831 831 LYS LYS A . n A 1 116 ILE 116 832 832 ILE ILE A . n A 1 117 LEU 117 833 833 LEU LEU A . n A 1 118 THR 118 834 834 THR THR A . n A 1 119 LYS 119 835 835 LYS LYS A . n A 1 120 GLU 120 836 836 GLU GLU A . n A 1 121 SER 121 837 837 SER SER A . n A 1 122 SER 122 838 838 SER SER A . n A 1 123 ARG 123 839 839 ARG ARG A . n A 1 124 GLU 124 840 840 GLU GLU A . n A 1 125 GLU 125 841 841 GLU GLU A . n A 1 126 LEU 126 842 842 LEU LEU A . n A 1 127 LEU 127 843 843 LEU LEU A . n A 1 128 SER 128 844 844 SER SER A . n A 1 129 PHE 129 845 845 PHE PHE A . n A 1 130 ILE 130 846 846 ILE ILE A . n A 1 131 GLN 131 847 847 GLN GLN A . n A 1 132 HIS 132 848 848 HIS HIS A . n A 1 133 TYR 133 849 849 TYR TYR A . n A 1 134 GLY 134 850 850 GLY GLY A . n A 1 135 SER 135 851 851 SER SER A . n A 1 136 HIS 136 852 852 HIS HIS A . n A 1 137 TYR 137 853 853 TYR TYR A . n A 1 138 ILE 138 854 854 ILE ILE A . n A 1 139 ALA 139 855 855 ALA ALA A . n A 1 140 GLU 140 856 856 GLU GLU A . n A 1 141 ALA 141 857 857 ALA ALA A . n A 1 142 LEU 142 858 858 LEU LEU A . n A 1 143 TYR 143 859 859 TYR TYR A . n A 1 144 GLY 144 860 860 GLY GLY A . n A 1 145 SER 145 861 861 SER SER A . n A 1 146 GLU 146 862 862 GLU GLU A . n A 1 147 LEU 147 863 863 LEU LEU A . n A 1 148 THR 148 864 864 THR THR A . n A 1 149 CYS 149 865 865 CYS CYS A . n A 1 150 ILE 150 866 866 ILE ILE A . n A 1 151 ILE 151 867 867 ILE ILE A . n A 1 152 HIS 152 868 868 HIS HIS A . n A 1 153 PHE 153 869 869 PHE PHE A . n A 1 154 PRO 154 870 870 PRO PRO A . n A 1 155 SER 155 871 871 SER SER A . n A 1 156 LYS 156 872 872 LYS LYS A . n A 1 157 LYS 157 873 873 LYS LYS A . n A 1 158 VAL 158 874 874 VAL VAL A . n A 1 159 GLN 159 875 875 GLN GLN A . n A 1 160 GLN 160 876 876 GLN GLN A . n A 1 161 GLN 161 877 877 GLN GLN A . n A 1 162 LEU 162 878 878 LEU LEU A . n A 1 163 TRP 163 879 879 TRP TRP A . n A 1 164 LEU 164 880 880 LEU LEU A . n A 1 165 GLN 165 881 881 GLN GLN A . n A 1 166 TYR 166 882 882 TYR TYR A . n A 1 167 GLN 167 883 883 GLN GLN A . n A 1 168 LYS 168 884 884 LYS LYS A . n A 1 169 GLU 169 885 885 GLU GLU A . n A 1 170 THR 170 886 886 THR THR A . n A 1 171 THR 171 887 887 THR THR A . n A 1 172 GLU 172 888 ? ? ? A . n A 1 173 LEU 173 889 ? ? ? A . n A 1 174 GLY 174 890 ? ? ? A . n A 1 175 SER 175 891 ? ? ? A . n A 1 176 LYS 176 892 ? ? ? A . n A 1 177 LYS 177 893 ? ? ? A . n A 1 178 GLU 178 894 ? ? ? A . n A 1 179 LEU 179 895 ? ? ? A . n A 1 180 LYS 180 896 ? ? ? A . n A 1 181 SER 181 897 897 SER SER A . n A 1 182 MET 182 898 898 MET MET A . n A 1 183 PRO 183 899 899 PRO PRO A . n A 1 184 PHE 184 900 900 PHE PHE A . n A 1 185 ILE 185 901 901 ILE ILE A . n A 1 186 THR 186 902 902 THR THR A . n A 1 187 TYR 187 903 903 TYR TYR A . n A 1 188 LEU 188 904 904 LEU LEU A . n A 1 189 SER 189 905 905 SER SER A . n A 1 190 GLY 190 906 906 GLY GLY A . n A 1 191 LEU 191 907 907 LEU LEU A . n A 1 192 LEU 192 908 908 LEU LEU A . n A 1 193 THR 193 909 909 THR THR A . n A 1 194 ALA 194 910 910 ALA ALA A . n A 1 195 GLN 195 911 911 GLN GLN A . n A 1 196 MET 196 912 912 MET MET A . n A 1 197 LEU 197 913 913 LEU LEU A . n A 1 198 SER 198 914 914 SER SER A . n A 1 199 ASP 199 915 915 ASP ASP A . n A 1 200 ASP 200 916 916 ASP ASP A . n A 1 201 GLN 201 917 917 GLN GLN A . n A 1 202 LEU 202 918 918 LEU LEU A . n A 1 203 ILE 203 919 919 ILE ILE A . n A 1 204 SER 204 920 920 SER SER A . n A 1 205 GLY 205 921 921 GLY GLY A . n A 1 206 VAL 206 922 922 VAL VAL A . n A 1 207 GLU 207 923 923 GLU GLU A . n A 1 208 ILE 208 924 924 ILE ILE A . n A 1 209 ARG 209 925 925 ARG ARG A . n A 1 210 CYS 210 926 926 CYS CYS A . n A 1 211 GLU 211 927 927 GLU GLU A . n A 1 212 GLU 212 928 928 GLU GLU A . n A 1 213 LYS 213 929 929 LYS LYS A . n A 1 214 GLY 214 930 930 GLY GLY A . n A 1 215 ARG 215 931 931 ARG ARG A . n A 1 216 CYS 216 932 932 CYS CYS A . n A 1 217 PRO 217 933 933 PRO PRO A . n A 1 218 SER 218 934 934 SER SER A . n A 1 219 THR 219 935 935 THR THR A . n A 1 220 CYS 220 936 936 CYS CYS A . n A 1 221 HIS 221 937 937 HIS HIS A . n A 1 222 LEU 222 938 938 LEU LEU A . n A 1 223 CYS 223 939 939 CYS CYS A . n A 1 224 ARG 224 940 940 ARG ARG A . n A 1 225 ARG 225 941 941 ARG ARG A . n A 1 226 PRO 226 942 942 PRO PRO A . n A 1 227 GLY 227 943 943 GLY GLY A . n A 1 228 LYS 228 944 944 LYS LYS A . n A 1 229 GLU 229 945 945 GLU GLU A . n A 1 230 GLN 230 946 946 GLN GLN A . n A 1 231 LEU 231 947 947 LEU LEU A . n A 1 232 SER 232 948 948 SER SER A . n A 1 233 PRO 233 949 949 PRO PRO A . n A 1 234 THR 234 950 950 THR THR A . n A 1 235 PRO 235 951 951 PRO PRO A . n A 1 236 VAL 236 952 952 VAL VAL A . n A 1 237 LEU 237 953 953 LEU LEU A . n A 1 238 LEU 238 954 954 LEU LEU A . n A 1 239 GLU 239 955 955 GLU GLU A . n A 1 240 ILE 240 956 956 ILE ILE A . n A 1 241 ASN 241 957 957 ASN ASN A . n A 1 242 ARG 242 958 958 ARG ARG A . n A 1 243 VAL 243 959 959 VAL VAL A . n A 1 244 VAL 244 960 960 VAL VAL A . n A 1 245 PRO 245 961 961 PRO PRO A . n A 1 246 LEU 246 962 962 LEU LEU A . n A 1 247 TYR 247 963 963 TYR TYR A . n A 1 248 THR 248 964 964 THR THR A . n A 1 249 LEU 249 965 965 LEU LEU A . n A 1 250 ILE 250 966 966 ILE ILE A . n A 1 251 GLN 251 967 967 GLN GLN A . n A 1 252 ASP 252 968 968 ASP ASP A . n A 1 253 ASN 253 969 969 ASN ASN A . n A 1 254 GLY 254 970 970 GLY GLY A . n A 1 255 THR 255 971 971 THR THR A . n A 1 256 LYS 256 972 972 LYS LYS A . n A 1 257 GLU 257 973 973 GLU GLU A . n A 1 258 ALA 258 974 974 ALA ALA A . n A 1 259 PHE 259 975 975 PHE PHE A . n A 1 260 LYS 260 976 976 LYS LYS A . n A 1 261 SER 261 977 977 SER SER A . n A 1 262 ALA 262 978 978 ALA ALA A . n A 1 263 LEU 263 979 979 LEU LEU A . n A 1 264 MET 264 980 980 MET MET A . n A 1 265 SER 265 981 981 SER SER A . n A 1 266 SER 266 982 982 SER SER A . n A 1 267 TYR 267 983 983 TYR TYR A . n A 1 268 TRP 268 984 984 TRP TRP A . n A 1 269 CYS 269 985 985 CYS CYS A . n A 1 270 SER 270 986 986 SER SER A . n A 1 271 GLY 271 987 987 GLY GLY A . n A 1 272 LYS 272 988 988 LYS LYS A . n A 1 273 GLY 273 989 989 GLY GLY A . n A 1 274 ASP 274 990 990 ASP ASP A . n A 1 275 VAL 275 991 991 VAL VAL A . n A 1 276 ILE 276 992 992 ILE ILE A . n A 1 277 ASP 277 993 993 ASP ASP A . n A 1 278 ASP 278 994 994 ASP ASP A . n A 1 279 TRP 279 995 995 TRP TRP A . n A 1 280 CYS 280 996 996 CYS CYS A . n A 1 281 ARG 281 997 997 ARG ARG A . n A 1 282 CYS 282 998 998 CYS CYS A . n A 1 283 ASP 283 999 999 ASP ASP A . n A 1 284 LEU 284 1000 1000 LEU LEU A . n A 1 285 SER 285 1001 1001 SER SER A . n A 1 286 ALA 286 1002 1002 ALA ALA A . n A 1 287 PHE 287 1003 1003 PHE PHE A . n A 1 288 ASP 288 1004 1004 ASP ASP A . n A 1 289 ALA 289 1005 1005 ALA ALA A . n A 1 290 ASN 290 1006 1006 ASN ASN A . n A 1 291 GLY 291 1007 1007 GLY GLY A . n A 1 292 LEU 292 1008 1008 LEU LEU A . n A 1 293 PRO 293 1009 1009 PRO PRO A . n A 1 294 ASN 294 1010 1010 ASN ASN A . n A 1 295 CYS 295 1011 1011 CYS CYS A . n A 1 296 SER 296 1012 1012 SER SER A . n A 1 297 PRO 297 1013 1013 PRO PRO A . n A 1 298 LEU 298 1014 1014 LEU LEU A . n A 1 299 LEU 299 1015 1015 LEU LEU A . n A 1 300 GLN 300 1016 1016 GLN GLN A . n A 1 301 PRO 301 1017 1017 PRO PRO A . n A 1 302 VAL 302 1018 1018 VAL VAL A . n A 1 303 LEU 303 1019 1019 LEU LEU A . n A 1 304 ARG 304 1020 1020 ARG ARG A . n A 1 305 LEU 305 1021 1021 LEU LEU A . n A 1 306 SER 306 1022 1022 SER SER A . n A 1 307 PRO 307 1023 1023 PRO PRO A . n A 1 308 THR 308 1024 1024 THR THR A . n A 1 309 VAL 309 1025 1025 VAL VAL A . n A 1 310 GLU 310 1026 1026 GLU GLU A . n A 1 311 PRO 311 1027 1027 PRO PRO A . n A 1 312 SER 312 1028 1028 SER SER A . n A 1 313 SER 313 1029 1029 SER SER A . n A 1 314 THR 314 1030 1030 THR THR A . n A 1 315 VAL 315 1031 1031 VAL VAL A . n A 1 316 VAL 316 1032 1032 VAL VAL A . n A 1 317 SER 317 1033 1033 SER SER A . n A 1 318 LEU 318 1034 1034 LEU LEU A . n A 1 319 GLU 319 1035 1035 GLU GLU A . n A 1 320 TRP 320 1036 1036 TRP TRP A . n A 1 321 VAL 321 1037 1037 VAL VAL A . n A 1 322 ASP 322 1038 1038 ASP ASP A . n A 1 323 VAL 323 1039 1039 VAL VAL A . n A 1 324 GLN 324 1040 1040 GLN GLN A . n A 1 325 PRO 325 1041 1041 PRO PRO A . n A 1 326 ALA 326 1042 1042 ALA ALA A . n A 1 327 ILE 327 1043 1043 ILE ILE A . n A 1 328 GLY 328 1044 1044 GLY GLY A . n A 1 329 THR 329 1045 1045 THR THR A . n A 1 330 LYS 330 1046 1046 LYS LYS A . n A 1 331 VAL 331 1047 1047 VAL VAL A . n A 1 332 SER 332 1048 1048 SER SER A . n A 1 333 ASP 333 1049 1049 ASP ASP A . n A 1 334 TYR 334 1050 1050 TYR TYR A . n A 1 335 ILE 335 1051 1051 ILE ILE A . n A 1 336 LEU 336 1052 1052 LEU LEU A . n A 1 337 GLN 337 1053 1053 GLN GLN A . n A 1 338 HIS 338 1054 1054 HIS HIS A . n A 1 339 LYS 339 1055 1055 LYS LYS A . n A 1 340 LYS 340 1056 1056 LYS LYS A . n A 1 341 VAL 341 1057 1057 VAL VAL A . n A 1 342 ASP 342 1058 1058 ASP ASP A . n A 1 343 GLU 343 1059 ? ? ? A . n A 1 344 TYR 344 1060 ? ? ? A . n A 1 345 THR 345 1061 ? ? ? A . n A 1 346 ASP 346 1062 ? ? ? A . n A 1 347 THR 347 1063 1063 THR THR A . n A 1 348 ASP 348 1064 1064 ASP ASP A . n A 1 349 LEU 349 1065 1065 LEU LEU A . n A 1 350 TYR 350 1066 1066 TYR TYR A . n A 1 351 THR 351 1067 1067 THR THR A . n A 1 352 GLY 352 1068 1068 GLY GLY A . n A 1 353 GLU 353 1069 1069 GLU GLU A . n A 1 354 PHE 354 1070 1070 PHE PHE A . n A 1 355 LEU 355 1071 1071 LEU LEU A . n A 1 356 SER 356 1072 1072 SER SER A . n A 1 357 PHE 357 1073 1073 PHE PHE A . n A 1 358 ALA 358 1074 1074 ALA ALA A . n A 1 359 ASP 359 1075 1075 ASP ASP A . n A 1 360 ASP 360 1076 1076 ASP ASP A . n A 1 361 LEU 361 1077 1077 LEU LEU A . n A 1 362 LEU 362 1078 1078 LEU LEU A . n A 1 363 SER 363 1079 1079 SER SER A . n A 1 364 GLY 364 1080 1080 GLY GLY A . n A 1 365 LEU 365 1081 1081 LEU LEU A . n A 1 366 GLY 366 1082 1082 GLY GLY A . n A 1 367 THR 367 1083 1083 THR THR A . n A 1 368 SER 368 1084 1084 SER SER A . n A 1 369 CYS 369 1085 1085 CYS CYS A . n A 1 370 VAL 370 1086 1086 VAL VAL A . n A 1 371 ALA 371 1087 1087 ALA ALA A . n A 1 372 ALA 372 1088 1088 ALA ALA A . n A 1 373 GLY 373 1089 1089 GLY GLY A . n A 1 374 ARG 374 1090 1090 ARG ARG A . n A 1 375 SER 375 1091 1091 SER SER A . n A 1 376 HIS 376 1092 1092 HIS HIS A . n A 1 377 GLY 377 1093 1093 GLY GLY A . n A 1 378 GLU 378 1094 1094 GLU GLU A . n A 1 379 VAL 379 1095 1095 VAL VAL A . n A 1 380 PRO 380 1096 1096 PRO PRO A . n A 1 381 GLU 381 1097 1097 GLU GLU A . n A 1 382 VAL 382 1098 1098 VAL VAL A . n A 1 383 SER 383 1099 1099 SER SER A . n A 1 384 ILE 384 1100 1100 ILE ILE A . n A 1 385 TYR 385 1101 1101 TYR TYR A . n A 1 386 SER 386 1102 1102 SER SER A . n A 1 387 VAL 387 1103 1103 VAL VAL A . n A 1 388 ILE 388 1104 1104 ILE ILE A . n A 1 389 PHE 389 1105 1105 PHE PHE A . n A 1 390 LYS 390 1106 1106 LYS LYS A . n A 1 391 CYS 391 1107 1107 CYS CYS A . n A 1 392 LEU 392 1108 1108 LEU LEU A . n A 1 393 GLU 393 1109 1109 GLU GLU A . n A 1 394 PRO 394 1110 1110 PRO PRO A . n A 1 395 ASP 395 1111 1111 ASP ASP A . n A 1 396 GLY 396 1112 1112 GLY GLY A . n A 1 397 LEU 397 1113 1113 LEU LEU A . n A 1 398 TYR 398 1114 1114 TYR TYR A . n A 1 399 LYS 399 1115 1115 LYS LYS A . n A 1 400 PHE 400 1116 1116 PHE PHE A . n A 1 401 THR 401 1117 1117 THR THR A . n A 1 402 LEU 402 1118 1118 LEU LEU A . n A 1 403 TYR 403 1119 1119 TYR TYR A . n A 1 404 ALA 404 1120 1120 ALA ALA A . n A 1 405 VAL 405 1121 1121 VAL VAL A . n A 1 406 ASP 406 1122 1122 ASP ASP A . n A 1 407 THR 407 1123 1123 THR THR A . n A 1 408 ARG 408 1124 1124 ARG ARG A . n A 1 409 GLY 409 1125 1125 GLY GLY A . n A 1 410 ARG 410 1126 1126 ARG ARG A . n A 1 411 HIS 411 1127 1127 HIS HIS A . n A 1 412 SER 412 1128 1128 SER SER A . n A 1 413 GLU 413 1129 1129 GLU GLU A . n A 1 414 LEU 414 1130 1130 LEU LEU A . n A 1 415 SER 415 1131 1131 SER SER A . n A 1 416 THR 416 1132 1132 THR THR A . n A 1 417 VAL 417 1133 1133 VAL VAL A . n A 1 418 THR 418 1134 1134 THR THR A . n A 1 419 LEU 419 1135 1135 LEU LEU A . n A 1 420 ARG 420 1136 1136 ARG ARG A . n A 1 421 THR 421 1137 1137 THR THR A . n A 1 422 ALA 422 1138 1138 ALA ALA A . n A 1 423 CYS 423 1139 1139 CYS CYS A . n A 1 424 PRO 424 1140 1140 PRO PRO A . n A 1 425 LEU 425 1141 1141 LEU LEU A . n A 1 426 VAL 426 1142 1142 VAL VAL A . n A 1 427 ASP 427 1143 1143 ASP ASP A . n A 1 428 ASP 428 1144 1144 ASP ASP A . n A 1 429 ASN 429 1145 1145 ASN ASN A . n A 1 430 LYS 430 1146 1146 LYS LYS A . n A 1 431 ALA 431 1147 1147 ALA ALA A . n A 1 432 GLU 432 1148 1148 GLU GLU A . n A 1 433 GLU 433 1149 1149 GLU GLU A . n A 1 434 ILE 434 1150 1150 ILE ILE A . n A 1 435 ALA 435 1151 1151 ALA ALA A . n A 1 436 ASP 436 1152 1152 ASP ASP A . n A 1 437 LYS 437 1153 1153 LYS LYS A . n A 1 438 ILE 438 1154 1154 ILE ILE A . n A 1 439 TYR 439 1155 1155 TYR TYR A . n A 1 440 ASN 440 1156 1156 ASN ASN A . n A 1 441 LEU 441 1157 1157 LEU LEU A . n A 1 442 TYR 442 1158 1158 TYR TYR A . n A 1 443 ASN 443 1159 1159 ASN ASN A . n A 1 444 GLY 444 1160 1160 GLY GLY A . n A 1 445 TYR 445 1161 1161 TYR TYR A . n A 1 446 THR 446 1162 1162 THR THR A . n A 1 447 SER 447 1163 1163 SER SER A . n A 1 448 GLY 448 1164 1164 GLY GLY A . n A 1 449 LYS 449 1165 1165 LYS LYS A . n A 1 450 GLU 450 1166 1166 GLU GLU A . n A 1 451 GLN 451 1167 1167 GLN GLN A . n A 1 452 GLN 452 1168 1168 GLN GLN A . n A 1 453 MET 453 1169 1169 MET MET A . n A 1 454 ALA 454 1170 1170 ALA ALA A . n A 1 455 TYR 455 1171 1171 TYR TYR A . n A 1 456 ASN 456 1172 1172 ASN ASN A . n A 1 457 THR 457 1173 1173 THR THR A . n A 1 458 LEU 458 1174 1174 LEU LEU A . n A 1 459 MET 459 1175 1175 MET MET A . n A 1 460 GLU 460 1176 1176 GLU GLU A . n A 1 461 VAL 461 1177 1177 VAL VAL A . n A 1 462 SER 462 1178 1178 SER SER A . n A 1 463 ALA 463 1179 1179 ALA ALA A . n A 1 464 SER 464 1180 1180 SER SER A . n A 1 465 MET 465 1181 1181 MET MET A . n A 1 466 LEU 466 1182 1182 LEU LEU A . n A 1 467 PHE 467 1183 1183 PHE PHE A . n A 1 468 ARG 468 1184 1184 ARG ARG A . n A 1 469 VAL 469 1185 1185 VAL VAL A . n A 1 470 GLN 470 1186 1186 GLN GLN A . n A 1 471 HIS 471 1187 1187 HIS HIS A . n A 1 472 HIS 472 1188 1188 HIS HIS A . n A 1 473 TYR 473 1189 1189 TYR TYR A . n A 1 474 ASN 474 1190 1190 ASN ASN A . n A 1 475 SER 475 1191 1191 SER SER A . n A 1 476 HIS 476 1192 1192 HIS HIS A . n A 1 477 TYR 477 1193 1193 TYR TYR A . n A 1 478 GLU 478 1194 1194 GLU GLU A . n A 1 479 LYS 479 1195 1195 LYS LYS A . n A 1 480 PHE 480 1196 1196 PHE PHE A . n A 1 481 GLY 481 1197 1197 GLY GLY A . n A 1 482 ASP 482 1198 1198 ASP ASP A . n A 1 483 PHE 483 1199 1199 PHE PHE A . n A 1 484 VAL 484 1200 1200 VAL VAL A . n A 1 485 TRP 485 1201 1201 TRP TRP A . n A 1 486 ARG 486 1202 1202 ARG ARG A . n A 1 487 SER 487 1203 1203 SER SER A . n A 1 488 GLU 488 1204 1204 GLU GLU A . n A 1 489 ASP 489 1205 1205 ASP ASP A . n A 1 490 GLU 490 1206 1206 GLU GLU A . n A 1 491 LEU 491 1207 1207 LEU LEU A . n A 1 492 GLY 492 1208 1208 GLY GLY A . n A 1 493 PRO 493 1209 1209 PRO PRO A . n A 1 494 ARG 494 1210 1210 ARG ARG A . n A 1 495 LYS 495 1211 1211 LYS LYS A . n A 1 496 ALA 496 1212 1212 ALA ALA A . n A 1 497 HIS 497 1213 1213 HIS HIS A . n A 1 498 LEU 498 1214 1214 LEU LEU A . n A 1 499 ILE 499 1215 1215 ILE ILE A . n A 1 500 LEU 500 1216 1216 LEU LEU A . n A 1 501 ARG 501 1217 1217 ARG ARG A . n A 1 502 ARG 502 1218 1218 ARG ARG A . n A 1 503 LEU 503 1219 1219 LEU LEU A . n A 1 504 GLU 504 1220 1220 GLU GLU A . n A 1 505 ARG 505 1221 1221 ARG ARG A . n A 1 506 VAL 506 1222 1222 VAL VAL A . n A 1 507 SER 507 1223 1223 SER SER A . n A 1 508 SER 508 1224 1224 SER SER A . n A 1 509 HIS 509 1225 1225 HIS HIS A . n A 1 510 CYS 510 1226 1226 CYS CYS A . n A 1 511 SER 511 1227 1227 SER SER A . n A 1 512 SER 512 1228 1228 SER SER A . n A 1 513 LEU 513 1229 1229 LEU LEU A . n A 1 514 LEU 514 1230 1230 LEU LEU A . n A 1 515 ARG 515 1231 1231 ARG ARG A . n A 1 516 SER 516 1232 1232 SER SER A . n A 1 517 ALA 517 1233 1233 ALA ALA A . n A 1 518 TYR 518 1234 1234 TYR TYR A . n A 1 519 ILE 519 1235 1235 ILE ILE A . n A 1 520 GLN 520 1236 1236 GLN GLN A . n A 1 521 SER 521 1237 1237 SER SER A . n A 1 522 ARG 522 1238 1238 ARG ARG A . n A 1 523 VAL 523 1239 1239 VAL VAL A . n A 1 524 GLU 524 1240 1240 GLU GLU A . n A 1 525 THR 525 1241 1241 THR THR A . n A 1 526 VAL 526 1242 1242 VAL VAL A . n A 1 527 PRO 527 1243 1243 PRO PRO A . n A 1 528 TYR 528 1244 1244 TYR TYR A . n A 1 529 LEU 529 1245 1245 LEU LEU A . n A 1 530 PHE 530 1246 1246 PHE PHE A . n A 1 531 CYS 531 1247 1247 CYS CYS A . n A 1 532 ARG 532 1248 1248 ARG ARG A . n A 1 533 SER 533 1249 1249 SER SER A . n A 1 534 GLU 534 1250 1250 GLU GLU A . n A 1 535 GLU 535 1251 1251 GLU GLU A . n A 1 536 VAL 536 1252 1252 VAL VAL A . n A 1 537 ARG 537 1253 1253 ARG ARG A . n A 1 538 PRO 538 1254 1254 PRO PRO A . n A 1 539 ALA 539 1255 1255 ALA ALA A . n A 1 540 GLY 540 1256 1256 GLY GLY A . n A 1 541 MET 541 1257 1257 MET MET A . n A 1 542 VAL 542 1258 1258 VAL VAL A . n A 1 543 TRP 543 1259 1259 TRP TRP A . n A 1 544 TYR 544 1260 1260 TYR TYR A . n A 1 545 SER 545 1261 1261 SER SER A . n A 1 546 ILE 546 1262 1262 ILE ILE A . n A 1 547 LEU 547 1263 1263 LEU LEU A . n A 1 548 LYS 548 1264 1264 LYS LYS A . n A 1 549 ASP 549 1265 1265 ASP ASP A . n A 1 550 THR 550 1266 1266 THR THR A . n A 1 551 LYS 551 1267 1267 LYS LYS A . n A 1 552 ILE 552 1268 1268 ILE ILE A . n A 1 553 THR 553 1269 1269 THR THR A . n A 1 554 CYS 554 1270 1270 CYS CYS A . n A 1 555 GLU 555 1271 1271 GLU GLU A . n A 1 556 GLU 556 1272 1272 GLU GLU A . n A 1 557 LYS 557 1273 1273 LYS LYS A . n A 1 558 MET 558 1274 1274 MET MET A . n A 1 559 VAL 559 1275 1275 VAL VAL A . n A 1 560 SER 560 1276 1276 SER SER A . n A 1 561 MET 561 1277 1277 MET MET A . n A 1 562 ALA 562 1278 1278 ALA ALA A . n A 1 563 ARG 563 1279 1279 ARG ARG A . n A 1 564 ASN 564 1280 1280 ASN ASN A . n A 1 565 THR 565 1281 1281 THR THR A . n A 1 566 TYR 566 1282 1282 TYR TYR A . n A 1 567 GLY 567 1283 1283 GLY GLY A . n A 1 568 GLU 568 1284 1284 GLU GLU A . n A 1 569 SER 569 1285 1285 SER SER A . n A 1 570 LYS 570 1286 1286 LYS LYS A . n A 1 571 GLY 571 1287 1287 GLY GLY A . n A 1 572 ARG 572 1288 1288 ARG ARG A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 1300 1300 NAG NAG A . C 2 NAG 2 1301 1301 NAG NAG A . D 3 BMA 3 1302 1302 BMA BMA A . E 4 MAN 4 1303 1303 MAN MAN A . F 4 MAN 5 1304 1304 MAN MAN A . G 4 MAN 6 1305 1305 MAN MAN A . H 4 MAN 7 1306 1306 MAN MAN A . I 4 MAN 8 1307 1307 MAN MAN A . J 4 MAN 9 1308 1308 MAN MAN A . K 4 MAN 10 1309 1309 MAN MAN A . L 2 NAG 1 1310 1315 NAG NAG A . M 5 I3P 1 1311 1316 I3P I3P A . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 3430 ? 1 MORE 37 ? 1 'SSA (A^2)' 30300 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2016-05-25 2 'Structure model' 1 1 2016-06-15 3 'Structure model' 1 2 2017-09-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' Advisory 3 3 'Structure model' 'Author supporting evidence' # loop_ _pdbx_audit_revision_category.ordinal _pdbx_audit_revision_category.revision_ordinal _pdbx_audit_revision_category.data_content_type _pdbx_audit_revision_category.category 1 3 'Structure model' pdbx_audit_support 2 3 'Structure model' pdbx_unobs_or_zero_occ_residues # _pdbx_audit_revision_item.ordinal 1 _pdbx_audit_revision_item.revision_ordinal 3 _pdbx_audit_revision_item.data_content_type 'Structure model' _pdbx_audit_revision_item.item '_pdbx_audit_support.funding_organization' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(dev_2283: ???)' 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2 ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? xia2 ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? . 4 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ILE A 753 ? ? -129.84 -83.36 2 1 LYS A 754 ? ? -132.94 -94.77 3 1 PRO A 757 ? ? -67.70 -167.89 4 1 SER A 818 ? ? 179.97 122.06 5 1 SER A 914 ? ? -112.61 -152.12 6 1 ASP A 915 ? ? -144.44 -117.41 7 1 PRO A 942 ? ? -24.42 -60.33 8 1 SER A 948 ? ? 49.75 74.99 9 1 LEU A 954 ? ? -107.26 -64.31 10 1 ASP A 994 ? ? 86.98 -2.01 11 1 SER A 1001 ? ? -108.15 74.67 12 1 ASP A 1004 ? ? -82.21 -157.30 13 1 ASP A 1064 ? ? 65.69 152.75 14 1 TYR A 1161 ? ? 63.60 -75.19 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLU 888 ? A GLU 172 2 1 Y 1 A LEU 889 ? A LEU 173 3 1 Y 1 A GLY 890 ? A GLY 174 4 1 Y 1 A SER 891 ? A SER 175 5 1 Y 1 A LYS 892 ? A LYS 176 6 1 Y 1 A LYS 893 ? A LYS 177 7 1 Y 1 A GLU 894 ? A GLU 178 8 1 Y 1 A LEU 895 ? A LEU 179 9 1 Y 1 A LYS 896 ? A LYS 180 10 1 Y 1 A GLU 1059 ? A GLU 343 11 1 Y 1 A TYR 1060 ? A TYR 344 12 1 Y 1 A THR 1061 ? A THR 345 13 1 Y 1 A ASP 1062 ? A ASP 346 # _pdbx_audit_support.funding_organization 'Medical Research Council (United Kingdom)' _pdbx_audit_support.country 'United Kingdom' _pdbx_audit_support.grant_number MR/N000331/1 _pdbx_audit_support.ordinal 1 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 BETA-D-MANNOSE BMA 4 ALPHA-D-MANNOSE MAN 5 D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE I3P #