data_5HZ1 # _entry.id 5HZ1 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5HZ1 WWPDB D_1000217985 # loop_ _pdbx_database_related.db_name _pdbx_database_related.details _pdbx_database_related.db_id _pdbx_database_related.content_type PDB . 5HZ3 unspecified PDB . 5HZ0 unspecified PDB . 5HYX unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5HZ1 _pdbx_database_status.recvd_initial_deposition_date 2016-02-02 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site PDBJ _pdbx_database_status.process_site PDBJ _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal _audit_author.identifier_ORCID 'Song, W.' 1 ? 'Han, Z.' 2 ? 'Chai, J.' 3 ? # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country ? _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'To Be Published' _citation.journal_id_ASTM ? _citation.journal_id_CSD 0353 _citation.journal_id_ISSN ? _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume ? _citation.language ? _citation.page_first ? _citation.page_last ? _citation.title 'Plant Receptor' _citation.year ? _citation.database_id_CSD ? _citation.pdbx_database_id_DOI ? _citation.pdbx_database_id_PubMed ? _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Song, W.' 1 primary 'Han, Z.' 2 primary 'Chai, J.' 3 # _cell.length_a 183.466 _cell.length_b 183.466 _cell.length_c 87.610 _cell.angle_alpha 90.000 _cell.angle_beta 90.000 _cell.angle_gamma 120.000 _cell.entry_id 5HZ1 _cell.Z_PDB 9 _cell.pdbx_unique_axis ? # _symmetry.space_group_name_H-M 'H 3' _symmetry.entry_id 5HZ1 _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 146 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Probable LRR receptor-like serine/threonine-protein kinase At4g26540' 69202.875 1 2.7.11.1 'V64T, G81E, M82K, D83Q, N104Q' 'UNP residues 57-689' ? 2 polymer syn ASP-PTR-TRP-ARG-ALA-LYS-HIS-HIS-PRO-HYP-LYS-ASN-ASN 1763.826 1 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 4 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;CNWTGVKCNRRGEVSEIQLKEKQLQGSLPVTSLRSLKSLTSLTLSSLQLTGVIPKEIGDFTELELLDLSDNSLSGDIPVE IFRLKKLKTLSLNTNNLEGHIPMEIGNLSGLVELMLFDNKLSGEIPRSIGELKNLQVLRAGGNKNLRGELPWEIGNCENL VMLGLAETSLSGKLPASIGNLKRVQTIAIYTSLLSGPIPDEIGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLWQN NLVGKIPTELGNCPELWLIDFSENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEELTNCTKLTHLEIDNNLITGEIPS LMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQAIDLSYNSLSGSIPKEIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNL YRLRLNGNRLAGSIPSEIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTNSLSGSLLGTTLPKSLKFIDFSDNA LSSTLPPGIGLLTELTKLNLAKNRLSGEIPREISTCRSLQLLNLGENDFSGEIPDELGQIPSLAISLNLSCNRFVGEIPS RFSDLKNLGVLDVSHNQLTGNLNVLTDLQNLVSLNISYNDFSGDLPNTPFFRRLPLSDLASNRGLYISNAIST ; ;CNWTGVKCNRRGEVSEIQLKEKQLQGSLPVTSLRSLKSLTSLTLSSLQLTGVIPKEIGDFTELELLDLSDNSLSGDIPVE IFRLKKLKTLSLNTNNLEGHIPMEIGNLSGLVELMLFDNKLSGEIPRSIGELKNLQVLRAGGNKNLRGELPWEIGNCENL VMLGLAETSLSGKLPASIGNLKRVQTIAIYTSLLSGPIPDEIGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLWQN NLVGKIPTELGNCPELWLIDFSENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEELTNCTKLTHLEIDNNLITGEIPS LMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQAIDLSYNSLSGSIPKEIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNL YRLRLNGNRLAGSIPSEIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTNSLSGSLLGTTLPKSLKFIDFSDNA LSSTLPPGIGLLTELTKLNLAKNRLSGEIPREISTCRSLQLLNLGENDFSGEIPDELGQIPSLAISLNLSCNRFVGEIPS RFSDLKNLGVLDVSHNQLTGNLNVLTDLQNLVSLNISYNDFSGDLPNTPFFRRLPLSDLASNRGLYISNAIST ; B ? 2 'polypeptide(L)' no yes 'D(PTR)WRAKHHP(HZP)KNN' DYWRAKHHPPKNN A ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 CYS n 1 2 ASN n 1 3 TRP n 1 4 THR n 1 5 GLY n 1 6 VAL n 1 7 LYS n 1 8 CYS n 1 9 ASN n 1 10 ARG n 1 11 ARG n 1 12 GLY n 1 13 GLU n 1 14 VAL n 1 15 SER n 1 16 GLU n 1 17 ILE n 1 18 GLN n 1 19 LEU n 1 20 LYS n 1 21 GLU n 1 22 LYS n 1 23 GLN n 1 24 LEU n 1 25 GLN n 1 26 GLY n 1 27 SER n 1 28 LEU n 1 29 PRO n 1 30 VAL n 1 31 THR n 1 32 SER n 1 33 LEU n 1 34 ARG n 1 35 SER n 1 36 LEU n 1 37 LYS n 1 38 SER n 1 39 LEU n 1 40 THR n 1 41 SER n 1 42 LEU n 1 43 THR n 1 44 LEU n 1 45 SER n 1 46 SER n 1 47 LEU n 1 48 GLN n 1 49 LEU n 1 50 THR n 1 51 GLY n 1 52 VAL n 1 53 ILE n 1 54 PRO n 1 55 LYS n 1 56 GLU n 1 57 ILE n 1 58 GLY n 1 59 ASP n 1 60 PHE n 1 61 THR n 1 62 GLU n 1 63 LEU n 1 64 GLU n 1 65 LEU n 1 66 LEU n 1 67 ASP n 1 68 LEU n 1 69 SER n 1 70 ASP n 1 71 ASN n 1 72 SER n 1 73 LEU n 1 74 SER n 1 75 GLY n 1 76 ASP n 1 77 ILE n 1 78 PRO n 1 79 VAL n 1 80 GLU n 1 81 ILE n 1 82 PHE n 1 83 ARG n 1 84 LEU n 1 85 LYS n 1 86 LYS n 1 87 LEU n 1 88 LYS n 1 89 THR n 1 90 LEU n 1 91 SER n 1 92 LEU n 1 93 ASN n 1 94 THR n 1 95 ASN n 1 96 ASN n 1 97 LEU n 1 98 GLU n 1 99 GLY n 1 100 HIS n 1 101 ILE n 1 102 PRO n 1 103 MET n 1 104 GLU n 1 105 ILE n 1 106 GLY n 1 107 ASN n 1 108 LEU n 1 109 SER n 1 110 GLY n 1 111 LEU n 1 112 VAL n 1 113 GLU n 1 114 LEU n 1 115 MET n 1 116 LEU n 1 117 PHE n 1 118 ASP n 1 119 ASN n 1 120 LYS n 1 121 LEU n 1 122 SER n 1 123 GLY n 1 124 GLU n 1 125 ILE n 1 126 PRO n 1 127 ARG n 1 128 SER n 1 129 ILE n 1 130 GLY n 1 131 GLU n 1 132 LEU n 1 133 LYS n 1 134 ASN n 1 135 LEU n 1 136 GLN n 1 137 VAL n 1 138 LEU n 1 139 ARG n 1 140 ALA n 1 141 GLY n 1 142 GLY n 1 143 ASN n 1 144 LYS n 1 145 ASN n 1 146 LEU n 1 147 ARG n 1 148 GLY n 1 149 GLU n 1 150 LEU n 1 151 PRO n 1 152 TRP n 1 153 GLU n 1 154 ILE n 1 155 GLY n 1 156 ASN n 1 157 CYS n 1 158 GLU n 1 159 ASN n 1 160 LEU n 1 161 VAL n 1 162 MET n 1 163 LEU n 1 164 GLY n 1 165 LEU n 1 166 ALA n 1 167 GLU n 1 168 THR n 1 169 SER n 1 170 LEU n 1 171 SER n 1 172 GLY n 1 173 LYS n 1 174 LEU n 1 175 PRO n 1 176 ALA n 1 177 SER n 1 178 ILE n 1 179 GLY n 1 180 ASN n 1 181 LEU n 1 182 LYS n 1 183 ARG n 1 184 VAL n 1 185 GLN n 1 186 THR n 1 187 ILE n 1 188 ALA n 1 189 ILE n 1 190 TYR n 1 191 THR n 1 192 SER n 1 193 LEU n 1 194 LEU n 1 195 SER n 1 196 GLY n 1 197 PRO n 1 198 ILE n 1 199 PRO n 1 200 ASP n 1 201 GLU n 1 202 ILE n 1 203 GLY n 1 204 TYR n 1 205 CYS n 1 206 THR n 1 207 GLU n 1 208 LEU n 1 209 GLN n 1 210 ASN n 1 211 LEU n 1 212 TYR n 1 213 LEU n 1 214 TYR n 1 215 GLN n 1 216 ASN n 1 217 SER n 1 218 ILE n 1 219 SER n 1 220 GLY n 1 221 SER n 1 222 ILE n 1 223 PRO n 1 224 THR n 1 225 THR n 1 226 ILE n 1 227 GLY n 1 228 GLY n 1 229 LEU n 1 230 LYS n 1 231 LYS n 1 232 LEU n 1 233 GLN n 1 234 SER n 1 235 LEU n 1 236 LEU n 1 237 LEU n 1 238 TRP n 1 239 GLN n 1 240 ASN n 1 241 ASN n 1 242 LEU n 1 243 VAL n 1 244 GLY n 1 245 LYS n 1 246 ILE n 1 247 PRO n 1 248 THR n 1 249 GLU n 1 250 LEU n 1 251 GLY n 1 252 ASN n 1 253 CYS n 1 254 PRO n 1 255 GLU n 1 256 LEU n 1 257 TRP n 1 258 LEU n 1 259 ILE n 1 260 ASP n 1 261 PHE n 1 262 SER n 1 263 GLU n 1 264 ASN n 1 265 LEU n 1 266 LEU n 1 267 THR n 1 268 GLY n 1 269 THR n 1 270 ILE n 1 271 PRO n 1 272 ARG n 1 273 SER n 1 274 PHE n 1 275 GLY n 1 276 LYS n 1 277 LEU n 1 278 GLU n 1 279 ASN n 1 280 LEU n 1 281 GLN n 1 282 GLU n 1 283 LEU n 1 284 GLN n 1 285 LEU n 1 286 SER n 1 287 VAL n 1 288 ASN n 1 289 GLN n 1 290 ILE n 1 291 SER n 1 292 GLY n 1 293 THR n 1 294 ILE n 1 295 PRO n 1 296 GLU n 1 297 GLU n 1 298 LEU n 1 299 THR n 1 300 ASN n 1 301 CYS n 1 302 THR n 1 303 LYS n 1 304 LEU n 1 305 THR n 1 306 HIS n 1 307 LEU n 1 308 GLU n 1 309 ILE n 1 310 ASP n 1 311 ASN n 1 312 ASN n 1 313 LEU n 1 314 ILE n 1 315 THR n 1 316 GLY n 1 317 GLU n 1 318 ILE n 1 319 PRO n 1 320 SER n 1 321 LEU n 1 322 MET n 1 323 SER n 1 324 ASN n 1 325 LEU n 1 326 ARG n 1 327 SER n 1 328 LEU n 1 329 THR n 1 330 MET n 1 331 PHE n 1 332 PHE n 1 333 ALA n 1 334 TRP n 1 335 GLN n 1 336 ASN n 1 337 LYS n 1 338 LEU n 1 339 THR n 1 340 GLY n 1 341 ASN n 1 342 ILE n 1 343 PRO n 1 344 GLN n 1 345 SER n 1 346 LEU n 1 347 SER n 1 348 GLN n 1 349 CYS n 1 350 ARG n 1 351 GLU n 1 352 LEU n 1 353 GLN n 1 354 ALA n 1 355 ILE n 1 356 ASP n 1 357 LEU n 1 358 SER n 1 359 TYR n 1 360 ASN n 1 361 SER n 1 362 LEU n 1 363 SER n 1 364 GLY n 1 365 SER n 1 366 ILE n 1 367 PRO n 1 368 LYS n 1 369 GLU n 1 370 ILE n 1 371 PHE n 1 372 GLY n 1 373 LEU n 1 374 ARG n 1 375 ASN n 1 376 LEU n 1 377 THR n 1 378 LYS n 1 379 LEU n 1 380 LEU n 1 381 LEU n 1 382 LEU n 1 383 SER n 1 384 ASN n 1 385 ASP n 1 386 LEU n 1 387 SER n 1 388 GLY n 1 389 PHE n 1 390 ILE n 1 391 PRO n 1 392 PRO n 1 393 ASP n 1 394 ILE n 1 395 GLY n 1 396 ASN n 1 397 CYS n 1 398 THR n 1 399 ASN n 1 400 LEU n 1 401 TYR n 1 402 ARG n 1 403 LEU n 1 404 ARG n 1 405 LEU n 1 406 ASN n 1 407 GLY n 1 408 ASN n 1 409 ARG n 1 410 LEU n 1 411 ALA n 1 412 GLY n 1 413 SER n 1 414 ILE n 1 415 PRO n 1 416 SER n 1 417 GLU n 1 418 ILE n 1 419 GLY n 1 420 ASN n 1 421 LEU n 1 422 LYS n 1 423 ASN n 1 424 LEU n 1 425 ASN n 1 426 PHE n 1 427 VAL n 1 428 ASP n 1 429 ILE n 1 430 SER n 1 431 GLU n 1 432 ASN n 1 433 ARG n 1 434 LEU n 1 435 VAL n 1 436 GLY n 1 437 SER n 1 438 ILE n 1 439 PRO n 1 440 PRO n 1 441 ALA n 1 442 ILE n 1 443 SER n 1 444 GLY n 1 445 CYS n 1 446 GLU n 1 447 SER n 1 448 LEU n 1 449 GLU n 1 450 PHE n 1 451 LEU n 1 452 ASP n 1 453 LEU n 1 454 HIS n 1 455 THR n 1 456 ASN n 1 457 SER n 1 458 LEU n 1 459 SER n 1 460 GLY n 1 461 SER n 1 462 LEU n 1 463 LEU n 1 464 GLY n 1 465 THR n 1 466 THR n 1 467 LEU n 1 468 PRO n 1 469 LYS n 1 470 SER n 1 471 LEU n 1 472 LYS n 1 473 PHE n 1 474 ILE n 1 475 ASP n 1 476 PHE n 1 477 SER n 1 478 ASP n 1 479 ASN n 1 480 ALA n 1 481 LEU n 1 482 SER n 1 483 SER n 1 484 THR n 1 485 LEU n 1 486 PRO n 1 487 PRO n 1 488 GLY n 1 489 ILE n 1 490 GLY n 1 491 LEU n 1 492 LEU n 1 493 THR n 1 494 GLU n 1 495 LEU n 1 496 THR n 1 497 LYS n 1 498 LEU n 1 499 ASN n 1 500 LEU n 1 501 ALA n 1 502 LYS n 1 503 ASN n 1 504 ARG n 1 505 LEU n 1 506 SER n 1 507 GLY n 1 508 GLU n 1 509 ILE n 1 510 PRO n 1 511 ARG n 1 512 GLU n 1 513 ILE n 1 514 SER n 1 515 THR n 1 516 CYS n 1 517 ARG n 1 518 SER n 1 519 LEU n 1 520 GLN n 1 521 LEU n 1 522 LEU n 1 523 ASN n 1 524 LEU n 1 525 GLY n 1 526 GLU n 1 527 ASN n 1 528 ASP n 1 529 PHE n 1 530 SER n 1 531 GLY n 1 532 GLU n 1 533 ILE n 1 534 PRO n 1 535 ASP n 1 536 GLU n 1 537 LEU n 1 538 GLY n 1 539 GLN n 1 540 ILE n 1 541 PRO n 1 542 SER n 1 543 LEU n 1 544 ALA n 1 545 ILE n 1 546 SER n 1 547 LEU n 1 548 ASN n 1 549 LEU n 1 550 SER n 1 551 CYS n 1 552 ASN n 1 553 ARG n 1 554 PHE n 1 555 VAL n 1 556 GLY n 1 557 GLU n 1 558 ILE n 1 559 PRO n 1 560 SER n 1 561 ARG n 1 562 PHE n 1 563 SER n 1 564 ASP n 1 565 LEU n 1 566 LYS n 1 567 ASN n 1 568 LEU n 1 569 GLY n 1 570 VAL n 1 571 LEU n 1 572 ASP n 1 573 VAL n 1 574 SER n 1 575 HIS n 1 576 ASN n 1 577 GLN n 1 578 LEU n 1 579 THR n 1 580 GLY n 1 581 ASN n 1 582 LEU n 1 583 ASN n 1 584 VAL n 1 585 LEU n 1 586 THR n 1 587 ASP n 1 588 LEU n 1 589 GLN n 1 590 ASN n 1 591 LEU n 1 592 VAL n 1 593 SER n 1 594 LEU n 1 595 ASN n 1 596 ILE n 1 597 SER n 1 598 TYR n 1 599 ASN n 1 600 ASP n 1 601 PHE n 1 602 SER n 1 603 GLY n 1 604 ASP n 1 605 LEU n 1 606 PRO n 1 607 ASN n 1 608 THR n 1 609 PRO n 1 610 PHE n 1 611 PHE n 1 612 ARG n 1 613 ARG n 1 614 LEU n 1 615 PRO n 1 616 LEU n 1 617 SER n 1 618 ASP n 1 619 LEU n 1 620 ALA n 1 621 SER n 1 622 ASN n 1 623 ARG n 1 624 GLY n 1 625 LEU n 1 626 TYR n 1 627 ILE n 1 628 SER n 1 629 ASN n 1 630 ALA n 1 631 ILE n 1 632 SER n 1 633 THR n 2 1 ASP n 2 2 PTR n 2 3 TRP n 2 4 ARG n 2 5 ALA n 2 6 LYS n 2 7 HIS n 2 8 HIS n 2 9 PRO n 2 10 HZP n 2 11 LYS n 2 12 ASN n 2 13 ASN n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 633 _entity_src_gen.gene_src_common_name 'Mouse-ear cress' _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'At4g26540, M3E9.30' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Arabidopsis thaliana' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 3702 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Insect cell expression vector pTIE1' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 266783 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _pdbx_entity_src_syn.entity_id 2 _pdbx_entity_src_syn.pdbx_src_id 1 _pdbx_entity_src_syn.pdbx_alt_source_flag sample _pdbx_entity_src_syn.pdbx_beg_seq_num 1 _pdbx_entity_src_syn.pdbx_end_seq_num 13 _pdbx_entity_src_syn.organism_scientific Arabidopsis _pdbx_entity_src_syn.organism_common_name ? _pdbx_entity_src_syn.ncbi_taxonomy_id 3701 _pdbx_entity_src_syn.details ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 UNP Y4265_ARATH C0LGR3 ? 1 ;CNWVGVKCNRRGEVSEIQLKGMDLQGSLPVTSLRSLKSLTSLTLSSLNLTGVIPKEIGDFTELELLDLSDNSLSGDIPVE IFRLKKLKTLSLNTNNLEGHIPMEIGNLSGLVELMLFDNKLSGEIPRSIGELKNLQVLRAGGNKNLRGELPWEIGNCENL VMLGLAETSLSGKLPASIGNLKRVQTIAIYTSLLSGPIPDEIGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLWQN NLVGKIPTELGNCPELWLIDFSENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEELTNCTKLTHLEIDNNLITGEIPS LMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQAIDLSYNSLSGSIPKEIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNL YRLRLNGNRLAGSIPSEIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTNSLSGSLLGTTLPKSLKFIDFSDNA LSSTLPPGIGLLTELTKLNLAKNRLSGEIPREISTCRSLQLLNLGENDFSGEIPDELGQIPSLAISLNLSCNRFVGEIPS RFSDLKNLGVLDVSHNQLTGNLNVLTDLQNLVSLNISYNDFSGDLPNTPFFRRLPLSDLASNRGLYISNAIST ; 57 2 PDB 5HZ1 5HZ1 ? 2 ? 1 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5HZ1 B 1 ? 633 ? C0LGR3 57 ? 689 ? 61 689 2 2 5HZ1 A 1 ? 13 ? 5HZ1 44 ? 56 ? 44 56 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 5HZ1 THR B 4 ? UNP C0LGR3 VAL 60 'engineered mutation' 64 1 1 5HZ1 GLU B 21 ? UNP C0LGR3 GLY 77 'engineered mutation' 81 2 1 5HZ1 LYS B 22 ? UNP C0LGR3 MET 78 'engineered mutation' 82 3 1 5HZ1 GLN B 23 ? UNP C0LGR3 ASP 79 'engineered mutation' 83 4 1 5HZ1 GLN B 48 ? UNP C0LGR3 ASN 104 'engineered mutation' 104 5 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HZP 'L-peptide linking' n '(4S)-4-hydroxy-L-proline' ? 'C5 H9 N O3' 131.130 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 PTR 'L-peptide linking' n O-PHOSPHOTYROSINE PHOSPHONOTYROSINE 'C9 H12 N O6 P' 261.168 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5HZ1 _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 4.00 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 69.24 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '0.1 M MES monohydrate pH 6.0, 22% (v/v) polyethylene glycol (PEG) 400' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'OXFORD RUBY CCD' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2014-12-21 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol LAUE _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'SSRF BEAMLINE BL17U' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 1 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline BL17U _diffrn_source.pdbx_synchrotron_site SSRF # _reflns.entry_id 5HZ1 _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.observed_criterion_sigma_I ? _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 99.000 _reflns.d_resolution_high 2.59 _reflns.number_obs 33780 _reflns.number_all ? _reflns.percent_possible_obs 98.9 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 31.8000 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 5.20 _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_CC_half ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_chi_squared ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.details ? # _reflns_shell.d_res_high . _reflns_shell.d_res_low ? _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_obs ? _reflns_shell.percent_possible_all ? _reflns_shell.percent_possible_obs ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_obs ? _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_gt ? _reflns_shell.number_unique_gt ? _reflns_shell.percent_possible_gt ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.pdbx_redundancy ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_CC_half ? _reflns_shell.pdbx_R_split ? # _refine.entry_id 5HZ1 _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_d_res_high 2.5900 _refine.ls_d_res_low 35.4200 _refine.pdbx_ls_sigma_F 0.000 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_percent_reflns_obs 98.9100 _refine.ls_number_reflns_obs 33780 _refine.ls_number_reflns_all ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.ls_matrix_type ? _refine.pdbx_R_Free_selection_details ? _refine.details 'U VALUES : REFINED INDIVIDUALLY' _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.2342 _refine.ls_R_factor_R_work 0.2342 _refine.ls_wR_factor_R_work ? _refine.ls_R_factor_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_percent_reflns_R_free ? _refine.ls_number_reflns_R_free ? _refine.ls_number_reflns_R_work ? _refine.ls_R_factor_R_free_error ? _refine.B_iso_mean 25.6860 _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.pdbx_isotropic_thermal_model ? _refine.aniso_B[1][1] 1.1500 _refine.aniso_B[2][2] 1.1500 _refine.aniso_B[3][3] -3.7300 _refine.aniso_B[1][2] 1.1500 _refine.aniso_B[1][3] 0.0000 _refine.aniso_B[2][3] -0.0000 _refine.correlation_coeff_Fo_to_Fc 0.9340 _refine.correlation_coeff_Fo_to_Fc_free ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.overall_SU_R_free ? _refine.pdbx_overall_ESU_R 0.3630 _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.solvent_model_details MASK _refine.pdbx_solvent_vdw_probe_radii 1.2000 _refine.pdbx_solvent_ion_probe_radii 0.8000 _refine.pdbx_solvent_shrinkage_radii 0.8000 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.overall_FOM_work_R_set ? _refine.B_iso_max 214.610 _refine.B_iso_min 2.000 _refine.pdbx_overall_phase_error ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_R_factor_R_free_error_details ? # _refine_hist.cycle_id final _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.d_res_high 2.5900 _refine_hist.d_res_low 35.4200 _refine_hist.pdbx_number_atoms_ligand 56 _refine_hist.number_atoms_solvent 0 _refine_hist.number_atoms_total 4942 _refine_hist.pdbx_number_residues_total 636 _refine_hist.pdbx_B_iso_mean_ligand 23.67 _refine_hist.pdbx_number_atoms_protein 4886 _refine_hist.pdbx_number_atoms_nucleic_acid 0 # _refine_ls_shell.d_res_high 2.5910 _refine_ls_shell.d_res_low 2.6590 _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.percent_reflns_obs 91.5200 _refine_ls_shell.number_reflns_R_work 2310 _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_R_work 0.2930 _refine_ls_shell.R_factor_R_free ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free ? _refine_ls_shell.R_factor_R_free_error 0.0000 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.R_factor_obs ? # _struct.entry_id 5HZ1 _struct.title 'Plant peptide hormone receptor RGFR1 in complex with RGF3' _struct.pdbx_descriptor ;ASP-PTR-TRP-ARG-ALA-LYS-HIS-HIS-PRO-HYP-LYS-ASN-ASN, Probable LRR receptor-like serine/threonine-protein kinase At4g26540 (E.C.2.7.11.1) ; _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5HZ1 _struct_keywords.text 'Plant Receptor, TRANSFERASE' _struct_keywords.pdbx_keywords TRANSFERASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 3 ? E N N 3 ? F N N 3 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 PRO A 54 ? PHE A 60 ? PRO B 110 PHE B 116 5 ? 7 HELX_P HELX_P2 AA2 PRO A 78 ? LEU A 84 ? PRO B 134 LEU B 140 5 ? 7 HELX_P HELX_P3 AA3 PRO A 102 ? LEU A 108 ? PRO B 158 LEU B 164 5 ? 7 HELX_P HELX_P4 AA4 PRO A 126 ? LEU A 132 ? PRO B 182 LEU B 188 5 ? 7 HELX_P HELX_P5 AA5 PRO A 151 ? CYS A 157 ? PRO B 207 CYS B 213 5 ? 7 HELX_P HELX_P6 AA6 PRO A 175 ? LEU A 181 ? PRO B 231 LEU B 237 5 ? 7 HELX_P HELX_P7 AA7 PRO A 199 ? CYS A 205 ? PRO B 255 CYS B 261 5 ? 7 HELX_P HELX_P8 AA8 PRO A 223 ? LEU A 229 ? PRO B 279 LEU B 285 5 ? 7 HELX_P HELX_P9 AA9 PRO A 247 ? CYS A 253 ? PRO B 303 CYS B 309 5 ? 7 HELX_P HELX_P10 AB1 PRO A 271 ? LEU A 277 ? PRO B 327 LEU B 333 5 ? 7 HELX_P HELX_P11 AB2 PRO A 295 ? CYS A 301 ? PRO B 351 CYS B 357 5 ? 7 HELX_P HELX_P12 AB3 PRO A 319 ? LEU A 325 ? PRO B 375 LEU B 381 5 ? 7 HELX_P HELX_P13 AB4 PRO A 343 ? CYS A 349 ? PRO B 399 CYS B 405 5 ? 7 HELX_P HELX_P14 AB5 PRO A 367 ? LEU A 373 ? PRO B 423 LEU B 429 5 ? 7 HELX_P HELX_P15 AB6 PRO A 391 ? CYS A 397 ? PRO B 447 CYS B 453 5 ? 7 HELX_P HELX_P16 AB7 PRO A 415 ? LEU A 421 ? PRO B 471 LEU B 477 5 ? 7 HELX_P HELX_P17 AB8 PRO A 439 ? CYS A 445 ? PRO B 495 CYS B 501 5 ? 7 HELX_P HELX_P18 AB9 LEU A 463 ? LEU A 467 ? LEU B 519 LEU B 523 5 ? 5 HELX_P HELX_P19 AC1 PRO A 486 ? LEU A 492 ? PRO B 542 LEU B 548 5 ? 7 HELX_P HELX_P20 AC2 PRO A 510 ? CYS A 516 ? PRO B 566 CYS B 572 5 ? 7 HELX_P HELX_P21 AC3 PRO A 534 ? GLY A 538 ? PRO B 590 GLY B 594 5 ? 5 HELX_P HELX_P22 AC4 PRO A 559 ? LEU A 565 ? PRO B 615 LEU B 621 5 ? 7 HELX_P HELX_P23 AC5 LEU A 582 ? THR A 586 ? LEU B 638 THR B 642 5 ? 5 HELX_P HELX_P24 AC6 THR A 608 ? LEU A 614 ? THR B 664 LEU B 670 1 ? 7 HELX_P HELX_P25 AC7 PRO A 615 ? SER A 621 ? PRO B 671 SER B 677 1 ? 7 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order covale1 covale one ? A ASN 396 ND2 ? ? ? 1_555 C NAG . C1 ? ? B ASN 452 B NAG 701 1_555 ? ? ? ? ? ? ? 1.445 ? covale2 covale one ? A ASN 548 ND2 ? ? ? 1_555 E NAG . C1 ? ? B ASN 604 B NAG 703 1_555 ? ? ? ? ? ? ? 1.452 ? covale3 covale one ? A ASN 595 ND2 ? ? ? 1_555 F NAG . C1 ? ? B ASN 651 B NAG 704 1_555 ? ? ? ? ? ? ? 1.446 ? covale4 covale both ? B ASP 1 C ? ? ? 1_555 B PTR 2 N ? ? A ASP 44 A PTR 45 1_555 ? ? ? ? ? ? ? 1.328 ? covale5 covale both ? B PTR 2 C ? ? ? 1_555 B TRP 3 N ? ? A PTR 45 A TRP 46 1_555 ? ? ? ? ? ? ? 1.330 ? covale6 covale both ? B PRO 9 C ? ? ? 1_555 B HZP 10 N ? ? A PRO 52 A HZP 53 1_555 ? ? ? ? ? ? ? 1.328 ? covale7 covale both ? B HZP 10 C ? ? ? 1_555 B LYS 11 N ? ? A HZP 53 A LYS 54 1_555 ? ? ? ? ? ? ? 1.323 ? covale8 covale both ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? B NAG 701 B NAG 702 1_555 ? ? ? ? ? ? ? 1.446 ? # _struct_conn_type.id covale _struct_conn_type.criteria ? _struct_conn_type.reference ? # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 26 ? AA2 ? 5 ? AA3 ? 5 ? AA4 ? 2 ? AA5 ? 2 ? AA6 ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? parallel AA1 3 4 ? parallel AA1 4 5 ? parallel AA1 5 6 ? parallel AA1 6 7 ? parallel AA1 7 8 ? parallel AA1 8 9 ? parallel AA1 9 10 ? parallel AA1 10 11 ? parallel AA1 11 12 ? parallel AA1 12 13 ? parallel AA1 13 14 ? parallel AA1 14 15 ? parallel AA1 15 16 ? parallel AA1 16 17 ? parallel AA1 17 18 ? parallel AA1 18 19 ? parallel AA1 19 20 ? parallel AA1 20 21 ? parallel AA1 21 22 ? parallel AA1 22 23 ? parallel AA1 23 24 ? parallel AA1 24 25 ? parallel AA1 25 26 ? parallel AA2 1 2 ? parallel AA2 2 3 ? parallel AA2 3 4 ? parallel AA2 4 5 ? parallel AA3 1 2 ? parallel AA3 2 3 ? parallel AA3 3 4 ? parallel AA3 4 5 ? parallel AA4 1 2 ? parallel AA5 1 2 ? parallel AA6 1 2 ? parallel AA6 2 3 ? parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 VAL A 6 ? CYS A 8 ? VAL B 66 CYS B 68 AA1 2 VAL A 14 ? LYS A 20 ? VAL B 74 LYS B 80 AA1 3 SER A 41 ? SER A 45 ? SER B 97 SER B 101 AA1 4 LEU A 65 ? ASP A 67 ? LEU B 121 ASP B 123 AA1 5 THR A 89 ? SER A 91 ? THR B 145 SER B 147 AA1 6 GLU A 113 ? MET A 115 ? GLU B 169 MET B 171 AA1 7 VAL A 137 ? ARG A 139 ? VAL B 193 ARG B 195 AA1 8 MET A 162 ? GLY A 164 ? MET B 218 GLY B 220 AA1 9 THR A 186 ? ALA A 188 ? THR B 242 ALA B 244 AA1 10 ASN A 210 ? TYR A 212 ? ASN B 266 TYR B 268 AA1 11 SER A 234 ? LEU A 236 ? SER B 290 LEU B 292 AA1 12 LEU A 258 ? ASP A 260 ? LEU B 314 ASP B 316 AA1 13 GLU A 282 ? GLN A 284 ? GLU B 338 GLN B 340 AA1 14 HIS A 306 ? GLU A 308 ? HIS B 362 GLU B 364 AA1 15 MET A 330 ? PHE A 332 ? MET B 386 PHE B 388 AA1 16 ALA A 354 ? ASP A 356 ? ALA B 410 ASP B 412 AA1 17 LYS A 378 ? LEU A 380 ? LYS B 434 LEU B 436 AA1 18 ARG A 402 ? ARG A 404 ? ARG B 458 ARG B 460 AA1 19 PHE A 426 ? ASP A 428 ? PHE B 482 ASP B 484 AA1 20 PHE A 450 ? ASP A 452 ? PHE B 506 ASP B 508 AA1 21 PHE A 473 ? ASP A 475 ? PHE B 529 ASP B 531 AA1 22 LYS A 497 ? ASN A 499 ? LYS B 553 ASN B 555 AA1 23 LEU A 521 ? ASN A 523 ? LEU B 577 ASN B 579 AA1 24 SER A 546 ? ASN A 548 ? SER B 602 ASN B 604 AA1 25 VAL A 570 ? ASP A 572 ? VAL B 626 ASP B 628 AA1 26 SER A 593 ? ASN A 595 ? SER B 649 ASN B 651 AA2 1 SER A 122 ? GLY A 123 ? SER B 178 GLY B 179 AA2 2 ASN A 145 ? GLY A 148 ? ASN B 201 GLY B 204 AA2 3 SER A 169 ? GLY A 172 ? SER B 225 GLY B 228 AA2 4 LEU A 193 ? GLY A 196 ? LEU B 249 GLY B 252 AA2 5 SER A 217 ? ILE A 218 ? SER B 273 ILE B 274 AA3 1 THR A 315 ? GLY A 316 ? THR B 371 GLY B 372 AA3 2 LYS A 337 ? GLY A 340 ? LYS B 393 GLY B 396 AA3 3 SER A 361 ? GLY A 364 ? SER B 417 GLY B 420 AA3 4 ASP A 385 ? GLY A 388 ? ASP B 441 GLY B 444 AA3 5 ARG A 409 ? LEU A 410 ? ARG B 465 LEU B 466 AA4 1 SER A 459 ? GLY A 460 ? SER B 515 GLY B 516 AA4 2 ALA A 480 ? LEU A 481 ? ALA B 536 LEU B 537 AA5 1 SER A 530 ? GLU A 532 ? SER B 586 GLU B 588 AA5 2 ARG A 553 ? VAL A 555 ? ARG B 609 VAL B 611 AA6 1 THR A 579 ? GLY A 580 ? THR B 635 GLY B 636 AA6 2 ASP A 600 ? LEU A 605 ? ASP B 656 LEU B 661 AA6 3 GLY A 624 ? ILE A 627 ? GLY B 680 ILE B 683 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N LYS A 7 ? N LYS B 67 O SER A 15 ? O SER B 75 AA1 2 3 N ILE A 17 ? N ILE B 77 O THR A 43 ? O THR B 99 AA1 3 4 N LEU A 42 ? N LEU B 98 O LEU A 65 ? O LEU B 121 AA1 4 5 N LEU A 66 ? N LEU B 122 O SER A 91 ? O SER B 147 AA1 5 6 N LEU A 90 ? N LEU B 146 O MET A 115 ? O MET B 171 AA1 6 7 N LEU A 114 ? N LEU B 170 O ARG A 139 ? O ARG B 195 AA1 7 8 N LEU A 138 ? N LEU B 194 O GLY A 164 ? O GLY B 220 AA1 8 9 N LEU A 163 ? N LEU B 219 O ALA A 188 ? O ALA B 244 AA1 9 10 N ILE A 187 ? N ILE B 243 O TYR A 212 ? O TYR B 268 AA1 10 11 N LEU A 211 ? N LEU B 267 O LEU A 236 ? O LEU B 292 AA1 11 12 N LEU A 235 ? N LEU B 291 O ASP A 260 ? O ASP B 316 AA1 12 13 N ILE A 259 ? N ILE B 315 O GLN A 284 ? O GLN B 340 AA1 13 14 N LEU A 283 ? N LEU B 339 O HIS A 306 ? O HIS B 362 AA1 14 15 N LEU A 307 ? N LEU B 363 O MET A 330 ? O MET B 386 AA1 15 16 N PHE A 331 ? N PHE B 387 O ALA A 354 ? O ALA B 410 AA1 16 17 N ILE A 355 ? N ILE B 411 O LEU A 380 ? O LEU B 436 AA1 17 18 N LEU A 379 ? N LEU B 435 O ARG A 404 ? O ARG B 460 AA1 18 19 N LEU A 403 ? N LEU B 459 O ASP A 428 ? O ASP B 484 AA1 19 20 N VAL A 427 ? N VAL B 483 O ASP A 452 ? O ASP B 508 AA1 20 21 N LEU A 451 ? N LEU B 507 O ASP A 475 ? O ASP B 531 AA1 21 22 N ILE A 474 ? N ILE B 530 O ASN A 499 ? O ASN B 555 AA1 22 23 N LEU A 498 ? N LEU B 554 O ASN A 523 ? O ASN B 579 AA1 23 24 N LEU A 522 ? N LEU B 578 O ASN A 548 ? O ASN B 604 AA1 24 25 N LEU A 547 ? N LEU B 603 O ASP A 572 ? O ASP B 628 AA1 25 26 N LEU A 571 ? N LEU B 627 O SER A 593 ? O SER B 649 AA2 1 2 N GLY A 123 ? N GLY B 179 O ARG A 147 ? O ARG B 203 AA2 2 3 N GLY A 148 ? N GLY B 204 O SER A 171 ? O SER B 227 AA2 3 4 N GLY A 172 ? N GLY B 228 O SER A 195 ? O SER B 251 AA2 4 5 N LEU A 194 ? N LEU B 250 O SER A 217 ? O SER B 273 AA3 1 2 N GLY A 316 ? N GLY B 372 O THR A 339 ? O THR B 395 AA3 2 3 N LEU A 338 ? N LEU B 394 O SER A 361 ? O SER B 417 AA3 3 4 N LEU A 362 ? N LEU B 418 O ASP A 385 ? O ASP B 441 AA3 4 5 N LEU A 386 ? N LEU B 442 O ARG A 409 ? O ARG B 465 AA4 1 2 N GLY A 460 ? N GLY B 516 O ALA A 480 ? O ALA B 536 AA5 1 2 N GLY A 531 ? N GLY B 587 O VAL A 555 ? O VAL B 611 AA6 1 2 N GLY A 580 ? N GLY B 636 O SER A 602 ? O SER B 658 AA6 2 3 N LEU A 605 ? N LEU B 661 O TYR A 626 ? O TYR B 682 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software B ASN 452 ? 5 'binding site for Poly-Saccharide residues NAG B 701 through NAG B 702 bound to ASN B 452' AC2 Software B NAG 703 ? 5 'binding site for Mono-Saccharide NAG B 703 bound to ASN B 604' AC3 Software B NAG 704 ? 5 'binding site for Mono-Saccharide NAG B 704 bound to ASN B 651' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 5 LYS A 55 ? LYS B 111 . ? 6_565 ? 2 AC1 5 ARG A 83 ? ARG B 139 . ? 6_565 ? 3 AC1 5 LYS A 368 ? LYS B 424 . ? 1_555 ? 4 AC1 5 ASP A 393 ? ASP B 449 . ? 1_555 ? 5 AC1 5 ASN A 396 ? ASN B 452 . ? 1_555 ? 6 AC2 5 GLU A 526 ? GLU B 582 . ? 1_555 ? 7 AC2 5 ASN A 548 ? ASN B 604 . ? 1_555 ? 8 AC2 5 SER A 550 ? SER B 606 . ? 1_555 ? 9 AC2 5 ASP A 572 ? ASP B 628 . ? 1_555 ? 10 AC2 5 NAG F . ? NAG B 704 . ? 1_555 ? 11 AC3 5 ASP A 572 ? ASP B 628 . ? 1_555 ? 12 AC3 5 SER A 574 ? SER B 630 . ? 1_555 ? 13 AC3 5 SER A 593 ? SER B 649 . ? 1_555 ? 14 AC3 5 ASN A 595 ? ASN B 651 . ? 1_555 ? 15 AC3 5 NAG E . ? NAG B 703 . ? 1_555 ? # _atom_sites.entry_id 5HZ1 _atom_sites.fract_transf_matrix[1][1] 0.005451 _atom_sites.fract_transf_matrix[1][2] 0.003147 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] -0.000000 _atom_sites.fract_transf_matrix[2][2] 0.006294 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] -0.000000 _atom_sites.fract_transf_matrix[3][3] 0.011414 _atom_sites.fract_transf_vector[1] 0.000000 _atom_sites.fract_transf_vector[2] 0.000000 _atom_sites.fract_transf_vector[3] 0.000000 # loop_ _atom_type.symbol C N O P S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . CYS A 1 1 ? 70.174 67.966 -23.765 1.00 51.86 ? 61 CYS B N 1 ATOM 2 C CA . CYS A 1 1 ? 69.762 67.610 -22.408 1.00 64.91 ? 61 CYS B CA 1 ATOM 3 C C . CYS A 1 1 ? 68.894 68.699 -21.769 1.00 71.53 ? 61 CYS B C 1 ATOM 4 O O . CYS A 1 1 ? 67.671 68.645 -21.847 1.00 69.93 ? 61 CYS B O 1 ATOM 5 C CB . CYS A 1 1 ? 70.982 67.298 -21.524 1.00 65.50 ? 61 CYS B CB 1 ATOM 6 N N . ASN A 1 2 ? 69.523 69.641 -21.075 1.00 79.30 ? 62 ASN B N 1 ATOM 7 C CA . ASN A 1 2 ? 68.806 70.775 -20.480 1.00 77.94 ? 62 ASN B CA 1 ATOM 8 C C . ASN A 1 2 ? 68.861 72.161 -21.158 1.00 75.36 ? 62 ASN B C 1 ATOM 9 O O . ASN A 1 2 ? 68.287 73.108 -20.617 1.00 71.72 ? 62 ASN B O 1 ATOM 10 C CB . ASN A 1 2 ? 69.149 70.913 -18.992 1.00 77.93 ? 62 ASN B CB 1 ATOM 11 N N . TRP A 1 3 ? 69.528 72.304 -22.308 1.00 74.58 ? 63 TRP B N 1 ATOM 12 C CA . TRP A 1 3 ? 69.828 73.656 -22.831 1.00 74.45 ? 63 TRP B CA 1 ATOM 13 C C . TRP A 1 3 ? 68.550 74.393 -23.309 1.00 75.64 ? 63 TRP B C 1 ATOM 14 O O . TRP A 1 3 ? 67.453 73.822 -23.306 1.00 64.46 ? 63 TRP B O 1 ATOM 15 C CB . TRP A 1 3 ? 70.936 73.590 -23.918 1.00 117.41 ? 63 TRP B CB 1 ATOM 16 C CG . TRP A 1 3 ? 71.375 74.920 -24.579 1.00 118.04 ? 63 TRP B CG 1 ATOM 17 C CD1 . TRP A 1 3 ? 71.002 75.380 -25.817 1.00 116.89 ? 63 TRP B CD1 1 ATOM 18 C CD2 . TRP A 1 3 ? 72.272 75.917 -24.042 1.00 116.62 ? 63 TRP B CD2 1 ATOM 19 N NE1 . TRP A 1 3 ? 71.595 76.596 -26.074 1.00 116.33 ? 63 TRP B NE1 1 ATOM 20 C CE2 . TRP A 1 3 ? 72.378 76.948 -25.006 1.00 116.07 ? 63 TRP B CE2 1 ATOM 21 C CE3 . TRP A 1 3 ? 72.984 76.042 -22.844 1.00 111.55 ? 63 TRP B CE3 1 ATOM 22 C CZ2 . TRP A 1 3 ? 73.168 78.084 -24.806 1.00 111.33 ? 63 TRP B CZ2 1 ATOM 23 C CZ3 . TRP A 1 3 ? 73.766 77.173 -22.650 1.00 109.21 ? 63 TRP B CZ3 1 ATOM 24 C CH2 . TRP A 1 3 ? 73.850 78.177 -23.626 1.00 108.85 ? 63 TRP B CH2 1 ATOM 25 N N . THR A 1 4 ? 68.693 75.652 -23.721 1.00 80.61 ? 64 THR B N 1 ATOM 26 C CA . THR A 1 4 ? 67.538 76.537 -23.871 1.00 79.97 ? 64 THR B CA 1 ATOM 27 C C . THR A 1 4 ? 66.751 76.251 -25.143 1.00 81.62 ? 64 THR B C 1 ATOM 28 O O . THR A 1 4 ? 67.265 76.397 -26.256 1.00 85.22 ? 64 THR B O 1 ATOM 29 C CB . THR A 1 4 ? 67.959 78.026 -23.862 1.00 79.16 ? 64 THR B CB 1 ATOM 30 N N . GLY A 1 5 ? 65.488 75.869 -24.964 1.00 74.80 ? 65 GLY B N 1 ATOM 31 C CA . GLY A 1 5 ? 64.639 75.477 -26.075 1.00 65.78 ? 65 GLY B CA 1 ATOM 32 C C . GLY A 1 5 ? 64.377 73.982 -26.143 1.00 56.44 ? 65 GLY B C 1 ATOM 33 O O . GLY A 1 5 ? 63.524 73.528 -26.904 1.00 54.72 ? 65 GLY B O 1 ATOM 34 N N . VAL A 1 6 ? 65.107 73.212 -25.345 1.00 50.77 ? 66 VAL B N 1 ATOM 35 C CA . VAL A 1 6 ? 64.943 71.766 -25.337 1.00 46.32 ? 66 VAL B CA 1 ATOM 36 C C . VAL A 1 6 ? 64.085 71.326 -24.163 1.00 53.32 ? 66 VAL B C 1 ATOM 37 O O . VAL A 1 6 ? 64.152 71.900 -23.075 1.00 56.48 ? 66 VAL B O 1 ATOM 38 C CB . VAL A 1 6 ? 66.292 71.043 -25.252 1.00 44.13 ? 66 VAL B CB 1 ATOM 39 C CG1 . VAL A 1 6 ? 66.104 69.547 -25.451 1.00 47.31 ? 66 VAL B CG1 1 ATOM 40 C CG2 . VAL A 1 6 ? 67.252 71.591 -26.285 1.00 38.60 ? 66 VAL B CG2 1 ATOM 41 N N . LYS A 1 7 ? 63.259 70.316 -24.397 1.00 54.76 ? 67 LYS B N 1 ATOM 42 C CA . LYS A 1 7 ? 62.481 69.711 -23.332 1.00 55.76 ? 67 LYS B CA 1 ATOM 43 C C . LYS A 1 7 ? 62.631 68.194 -23.439 1.00 58.51 ? 67 LYS B C 1 ATOM 44 O O . LYS A 1 7 ? 62.830 67.663 -24.537 1.00 57.48 ? 67 LYS B O 1 ATOM 45 C CB . LYS A 1 7 ? 61.013 70.141 -23.425 1.00 55.64 ? 67 LYS B CB 1 ATOM 46 C CG . LYS A 1 7 ? 60.800 71.658 -23.373 1.00 58.22 ? 67 LYS B CG 1 ATOM 47 C CD . LYS A 1 7 ? 59.333 72.025 -23.611 1.00 59.24 ? 67 LYS B CD 1 ATOM 48 C CE . LYS A 1 7 ? 59.113 73.540 -23.692 1.00 58.90 ? 67 LYS B CE 1 ATOM 49 N NZ . LYS A 1 7 ? 57.680 73.914 -23.957 1.00 51.87 ? 67 LYS B NZ 1 ATOM 50 N N . CYS A 1 8 ? 62.565 67.502 -22.300 1.00 58.78 ? 68 CYS B N 1 ATOM 51 C CA . CYS A 1 8 ? 62.785 66.054 -22.270 1.00 57.52 ? 68 CYS B CA 1 ATOM 52 C C . CYS A 1 8 ? 61.626 65.286 -21.645 1.00 55.55 ? 68 CYS B C 1 ATOM 53 O O . CYS A 1 8 ? 60.835 65.849 -20.888 1.00 55.01 ? 68 CYS B O 1 ATOM 54 C CB . CYS A 1 8 ? 64.086 65.712 -21.536 1.00 59.24 ? 68 CYS B CB 1 ATOM 55 S SG . CYS A 1 8 ? 65.576 65.695 -22.565 1.00 87.30 ? 68 CYS B SG 1 ATOM 56 N N . ASN A 1 9 ? 61.535 63.999 -21.979 1.00 59.29 ? 69 ASN B N 1 ATOM 57 C CA . ASN A 1 9 ? 60.518 63.114 -21.424 1.00 66.66 ? 69 ASN B CA 1 ATOM 58 C C . ASN A 1 9 ? 60.880 62.701 -19.990 1.00 72.07 ? 69 ASN B C 1 ATOM 59 O O . ASN A 1 9 ? 61.957 63.044 -19.488 1.00 67.67 ? 69 ASN B O 1 ATOM 60 C CB . ASN A 1 9 ? 60.383 61.878 -22.322 1.00 69.66 ? 69 ASN B CB 1 ATOM 61 C CG . ASN A 1 9 ? 59.150 61.052 -22.006 1.00 80.04 ? 69 ASN B CG 1 ATOM 62 O OD1 . ASN A 1 9 ? 58.307 61.450 -21.194 1.00 84.78 ? 69 ASN B OD1 1 ATOM 63 N ND2 . ASN A 1 9 ? 59.034 59.895 -22.651 1.00 81.98 ? 69 ASN B ND2 1 ATOM 64 N N . ARG A 1 10 ? 59.995 61.959 -19.329 1.00 75.70 ? 70 ARG B N 1 ATOM 65 C CA . ARG A 1 10 ? 60.321 61.431 -18.010 1.00 79.22 ? 70 ARG B CA 1 ATOM 66 C C . ARG A 1 10 ? 61.324 60.281 -18.099 1.00 85.53 ? 70 ARG B C 1 ATOM 67 O O . ARG A 1 10 ? 62.093 60.056 -17.168 1.00 88.98 ? 70 ARG B O 1 ATOM 68 C CB . ARG A 1 10 ? 59.068 61.025 -17.223 1.00 76.71 ? 70 ARG B CB 1 ATOM 69 C CG . ARG A 1 10 ? 58.085 60.130 -17.959 1.00 78.47 ? 70 ARG B CG 1 ATOM 70 C CD . ARG A 1 10 ? 56.964 59.678 -17.019 1.00 77.77 ? 70 ARG B CD 1 ATOM 71 N NE . ARG A 1 10 ? 56.465 60.773 -16.184 1.00 74.44 ? 70 ARG B NE 1 ATOM 72 C CZ . ARG A 1 10 ? 55.857 60.608 -15.010 1.00 72.58 ? 70 ARG B CZ 1 ATOM 73 N NH1 . ARG A 1 10 ? 55.666 59.389 -14.516 1.00 73.17 ? 70 ARG B NH1 1 ATOM 74 N NH2 . ARG A 1 10 ? 55.447 61.665 -14.323 1.00 69.15 ? 70 ARG B NH2 1 ATOM 75 N N . ARG A 1 11 ? 61.343 59.574 -19.226 1.00 84.33 ? 71 ARG B N 1 ATOM 76 C CA . ARG A 1 11 ? 62.310 58.494 -19.417 1.00 80.88 ? 71 ARG B CA 1 ATOM 77 C C . ARG A 1 11 ? 63.659 59.036 -19.920 1.00 77.29 ? 71 ARG B C 1 ATOM 78 O O . ARG A 1 11 ? 64.576 58.268 -20.211 1.00 82.93 ? 71 ARG B O 1 ATOM 79 C CB . ARG A 1 11 ? 61.750 57.383 -20.327 1.00 85.87 ? 71 ARG B CB 1 ATOM 80 C CG . ARG A 1 11 ? 61.358 57.852 -21.716 1.00 97.65 ? 71 ARG B CG 1 ATOM 81 C CD . ARG A 1 11 ? 60.758 56.738 -22.564 1.00 105.31 ? 71 ARG B CD 1 ATOM 82 N NE . ARG A 1 11 ? 61.679 55.627 -22.823 1.00 111.28 ? 71 ARG B NE 1 ATOM 83 C CZ . ARG A 1 11 ? 61.589 54.828 -23.883 1.00 115.65 ? 71 ARG B CZ 1 ATOM 84 N NH1 . ARG A 1 11 ? 60.646 55.045 -24.795 1.00 115.67 ? 71 ARG B NH1 1 ATOM 85 N NH2 . ARG A 1 11 ? 62.459 53.841 -24.054 1.00 118.07 ? 71 ARG B NH2 1 ATOM 86 N N . GLY A 1 12 ? 63.765 60.361 -20.036 1.00 69.64 ? 72 GLY B N 1 ATOM 87 C CA . GLY A 1 12 ? 65.038 61.018 -20.312 1.00 62.06 ? 72 GLY B CA 1 ATOM 88 C C . GLY A 1 12 ? 65.382 61.359 -21.757 1.00 57.22 ? 72 GLY B C 1 ATOM 89 O O . GLY A 1 12 ? 66.476 61.869 -22.037 1.00 49.99 ? 72 GLY B O 1 ATOM 90 N N . GLU A 1 13 ? 64.452 61.077 -22.669 1.00 62.43 ? 73 GLU B N 1 ATOM 91 C CA . GLU A 1 13 ? 64.641 61.344 -24.095 1.00 65.46 ? 73 GLU B CA 1 ATOM 92 C C . GLU A 1 13 ? 64.099 62.715 -24.516 1.00 62.00 ? 73 GLU B C 1 ATOM 93 O O . GLU A 1 13 ? 63.094 63.192 -23.984 1.00 61.97 ? 73 GLU B O 1 ATOM 94 C CB . GLU A 1 13 ? 63.971 60.245 -24.912 1.00 70.23 ? 73 GLU B CB 1 ATOM 95 C CG . GLU A 1 13 ? 64.168 58.858 -24.329 1.00 77.79 ? 73 GLU B CG 1 ATOM 96 C CD . GLU A 1 13 ? 63.141 57.897 -24.853 1.00 85.62 ? 73 GLU B CD 1 ATOM 97 O OE1 . GLU A 1 13 ? 62.024 58.353 -25.198 1.00 84.99 ? 73 GLU B OE1 1 ATOM 98 O OE2 . GLU A 1 13 ? 63.457 56.696 -24.935 1.00 90.75 ? 73 GLU B OE2 1 ATOM 99 N N . VAL A 1 14 ? 64.781 63.352 -25.463 1.00 57.18 ? 74 VAL B N 1 ATOM 100 C CA . VAL A 1 14 ? 64.338 64.651 -25.945 1.00 53.60 ? 74 VAL B CA 1 ATOM 101 C C . VAL A 1 14 ? 62.943 64.551 -26.557 1.00 47.45 ? 74 VAL B C 1 ATOM 102 O O . VAL A 1 14 ? 62.711 63.814 -27.525 1.00 39.33 ? 74 VAL B O 1 ATOM 103 C CB . VAL A 1 14 ? 65.305 65.177 -27.012 1.00 50.50 ? 74 VAL B CB 1 ATOM 104 C CG1 . VAL A 1 14 ? 64.771 66.450 -27.625 1.00 41.66 ? 74 VAL B CG1 1 ATOM 105 C CG2 . VAL A 1 14 ? 66.695 65.389 -26.406 1.00 39.03 ? 74 VAL B CG2 1 ATOM 106 N N . SER A 1 15 ? 62.013 65.286 -25.958 1.00 43.55 ? 75 SER B N 1 ATOM 107 C CA . SER A 1 15 ? 60.643 65.292 -26.417 1.00 32.79 ? 75 SER B CA 1 ATOM 108 C C . SER A 1 15 ? 60.194 66.551 -27.165 1.00 42.93 ? 75 SER B C 1 ATOM 109 O O . SER A 1 15 ? 59.135 66.538 -27.785 1.00 39.06 ? 75 SER B O 1 ATOM 110 C CB . SER A 1 15 ? 59.729 65.040 -25.224 1.00 41.74 ? 75 SER B CB 1 ATOM 111 O OG . SER A 1 15 ? 58.490 64.497 -25.630 1.00 47.20 ? 75 SER B OG 1 ATOM 112 N N . GLU A 1 16 ? 60.989 67.621 -27.143 1.00 32.26 ? 76 GLU B N 1 ATOM 113 C CA . GLU A 1 16 ? 60.551 68.894 -27.730 1.00 32.78 ? 76 GLU B CA 1 ATOM 114 C C . GLU A 1 16 ? 61.696 69.793 -28.152 1.00 45.65 ? 76 GLU B C 1 ATOM 115 O O . GLU A 1 16 ? 62.752 69.803 -27.524 1.00 55.30 ? 76 GLU B O 1 ATOM 116 C CB . GLU A 1 16 ? 59.654 69.689 -26.773 1.00 36.33 ? 76 GLU B CB 1 ATOM 117 C CG . GLU A 1 16 ? 58.243 69.157 -26.604 1.00 44.97 ? 76 GLU B CG 1 ATOM 118 C CD . GLU A 1 16 ? 57.415 70.007 -25.663 1.00 55.84 ? 76 GLU B CD 1 ATOM 119 O OE1 . GLU A 1 16 ? 56.886 69.460 -24.668 1.00 51.84 ? 76 GLU B OE1 1 ATOM 120 O OE2 . GLU A 1 16 ? 57.292 71.224 -25.927 1.00 63.39 ? 76 GLU B OE2 1 ATOM 121 N N . ILE A 1 17 ? 61.457 70.570 -29.203 1.00 31.53 ? 77 ILE B N 1 ATOM 122 C CA . ILE A 1 17 ? 62.404 71.550 -29.692 1.00 37.35 ? 77 ILE B CA 1 ATOM 123 C C . ILE A 1 17 ? 61.624 72.800 -30.061 1.00 43.57 ? 77 ILE B C 1 ATOM 124 O O . ILE A 1 17 ? 60.661 72.733 -30.823 1.00 46.72 ? 77 ILE B O 1 ATOM 125 C CB . ILE A 1 17 ? 63.126 71.028 -30.934 1.00 40.66 ? 77 ILE B CB 1 ATOM 126 C CG1 . ILE A 1 17 ? 64.065 69.885 -30.557 1.00 39.31 ? 77 ILE B CG1 1 ATOM 127 C CG2 . ILE A 1 17 ? 63.882 72.146 -31.638 1.00 39.28 ? 77 ILE B CG2 1 ATOM 128 C CD1 . ILE A 1 17 ? 64.566 69.118 -31.752 1.00 34.82 ? 77 ILE B CD1 1 ATOM 129 N N . GLN A 1 18 ? 62.015 73.935 -29.499 1.00 46.37 ? 78 GLN B N 1 ATOM 130 C CA . GLN A 1 18 ? 61.332 75.183 -29.786 1.00 48.68 ? 78 GLN B CA 1 ATOM 131 C C . GLN A 1 18 ? 62.298 76.335 -30.004 1.00 58.75 ? 78 GLN B C 1 ATOM 132 O O . GLN A 1 18 ? 63.030 76.725 -29.091 1.00 61.34 ? 78 GLN B O 1 ATOM 133 C CB . GLN A 1 18 ? 60.384 75.526 -28.645 1.00 48.39 ? 78 GLN B CB 1 ATOM 134 C CG . GLN A 1 18 ? 59.756 76.893 -28.774 1.00 53.26 ? 78 GLN B CG 1 ATOM 135 C CD . GLN A 1 18 ? 58.434 76.978 -28.047 1.00 59.95 ? 78 GLN B CD 1 ATOM 136 O OE1 . GLN A 1 18 ? 57.653 76.023 -28.041 1.00 60.45 ? 78 GLN B OE1 1 ATOM 137 N NE2 . GLN A 1 18 ? 58.177 78.120 -27.422 1.00 62.04 ? 78 GLN B NE2 1 ATOM 138 N N . LEU A 1 19 ? 62.281 76.894 -31.209 1.00 61.08 ? 79 LEU B N 1 ATOM 139 C CA . LEU A 1 19 ? 63.099 78.058 -31.525 1.00 63.24 ? 79 LEU B CA 1 ATOM 140 C C . LEU A 1 19 ? 62.264 79.154 -32.191 1.00 65.36 ? 79 LEU B C 1 ATOM 141 O O . LEU A 1 19 ? 61.794 78.984 -33.315 1.00 61.54 ? 79 LEU B O 1 ATOM 142 C CB . LEU A 1 19 ? 64.246 77.652 -32.446 1.00 62.71 ? 79 LEU B CB 1 ATOM 143 C CG . LEU A 1 19 ? 65.144 76.509 -31.970 1.00 62.43 ? 79 LEU B CG 1 ATOM 144 C CD1 . LEU A 1 19 ? 66.278 76.275 -32.959 1.00 60.31 ? 79 LEU B CD1 1 ATOM 145 C CD2 . LEU A 1 19 ? 65.696 76.791 -30.582 1.00 61.06 ? 79 LEU B CD2 1 ATOM 146 N N . LYS A 1 20 ? 62.097 80.283 -31.508 1.00 69.70 ? 80 LYS B N 1 ATOM 147 C CA . LYS A 1 20 ? 61.295 81.383 -32.043 1.00 70.48 ? 80 LYS B CA 1 ATOM 148 C C . LYS A 1 20 ? 62.055 82.709 -32.134 1.00 80.10 ? 80 LYS B C 1 ATOM 149 O O . LYS A 1 20 ? 62.642 83.170 -31.156 1.00 83.85 ? 80 LYS B O 1 ATOM 150 C CB . LYS A 1 20 ? 60.002 81.567 -31.239 1.00 67.03 ? 80 LYS B CB 1 ATOM 151 C CG . LYS A 1 20 ? 58.929 80.525 -31.533 1.00 69.65 ? 80 LYS B CG 1 ATOM 152 C CD . LYS A 1 20 ? 57.571 80.921 -30.948 1.00 71.45 ? 80 LYS B CD 1 ATOM 153 C CE . LYS A 1 20 ? 56.717 81.703 -31.947 1.00 75.27 ? 80 LYS B CE 1 ATOM 154 N NZ . LYS A 1 20 ? 57.275 83.044 -32.286 1.00 78.20 ? 80 LYS B NZ 1 ATOM 155 N N . GLU A 1 21 ? 62.026 83.303 -33.326 1.00 85.64 ? 81 GLU B N 1 ATOM 156 C CA . GLU A 1 21 ? 62.618 84.615 -33.624 1.00 85.93 ? 81 GLU B CA 1 ATOM 157 C C . GLU A 1 21 ? 64.099 84.759 -33.276 1.00 85.78 ? 81 GLU B C 1 ATOM 158 O O . GLU A 1 21 ? 64.471 85.607 -32.463 1.00 87.06 ? 81 GLU B O 1 ATOM 159 C CB . GLU A 1 21 ? 61.815 85.729 -32.942 1.00 86.99 ? 81 GLU B CB 1 ATOM 160 N N . LYS A 1 22 ? 64.938 83.926 -33.884 1.00 85.13 ? 82 LYS B N 1 ATOM 161 C CA . LYS A 1 22 ? 66.389 84.043 -33.718 1.00 84.73 ? 82 LYS B CA 1 ATOM 162 C C . LYS A 1 22 ? 67.207 84.662 -34.873 1.00 86.50 ? 82 LYS B C 1 ATOM 163 O O . LYS A 1 22 ? 68.427 84.775 -34.750 1.00 92.46 ? 82 LYS B O 1 ATOM 164 C CB . LYS A 1 22 ? 67.001 82.719 -33.233 1.00 82.92 ? 82 LYS B CB 1 ATOM 165 N N . GLN A 1 23 ? 66.567 85.038 -35.983 1.00 81.37 ? 83 GLN B N 1 ATOM 166 C CA . GLN A 1 23 ? 67.292 85.659 -37.113 1.00 80.03 ? 83 GLN B CA 1 ATOM 167 C C . GLN A 1 23 ? 68.414 84.807 -37.742 1.00 80.15 ? 83 GLN B C 1 ATOM 168 O O . GLN A 1 23 ? 69.594 85.024 -37.475 1.00 85.42 ? 83 GLN B O 1 ATOM 169 C CB . GLN A 1 23 ? 67.825 87.050 -36.743 1.00 77.73 ? 83 GLN B CB 1 ATOM 170 N N . LEU A 1 24 ? 68.035 83.818 -38.543 1.00 74.30 ? 84 LEU B N 1 ATOM 171 C CA . LEU A 1 24 ? 68.977 82.866 -39.131 1.00 73.47 ? 84 LEU B CA 1 ATOM 172 C C . LEU A 1 24 ? 68.869 82.867 -40.649 1.00 81.24 ? 84 LEU B C 1 ATOM 173 O O . LEU A 1 24 ? 68.238 83.747 -41.236 1.00 82.78 ? 84 LEU B O 1 ATOM 174 C CB . LEU A 1 24 ? 68.679 81.443 -38.669 1.00 66.83 ? 84 LEU B CB 1 ATOM 175 C CG . LEU A 1 24 ? 68.889 80.950 -37.247 1.00 63.18 ? 84 LEU B CG 1 ATOM 176 C CD1 . LEU A 1 24 ? 67.958 81.643 -36.293 1.00 67.75 ? 84 LEU B CD1 1 ATOM 177 C CD2 . LEU A 1 24 ? 68.638 79.454 -37.226 1.00 57.14 ? 84 LEU B CD2 1 ATOM 178 N N . GLN A 1 25 ? 69.525 81.892 -41.279 1.00 84.62 ? 85 GLN B N 1 ATOM 179 C CA . GLN A 1 25 ? 69.366 81.644 -42.712 1.00 86.63 ? 85 GLN B CA 1 ATOM 180 C C . GLN A 1 25 ? 69.356 80.138 -43.001 1.00 84.27 ? 85 GLN B C 1 ATOM 181 O O . GLN A 1 25 ? 69.453 79.327 -42.080 1.00 79.49 ? 85 GLN B O 1 ATOM 182 C CB . GLN A 1 25 ? 70.495 82.317 -43.500 1.00 91.74 ? 85 GLN B CB 1 ATOM 183 C CG . GLN A 1 25 ? 70.061 82.936 -44.826 1.00 93.27 ? 85 GLN B CG 1 ATOM 184 C CD . GLN A 1 25 ? 69.612 84.381 -44.680 1.00 92.71 ? 85 GLN B CD 1 ATOM 185 O OE1 . GLN A 1 25 ? 69.823 85.007 -43.640 1.00 94.84 ? 85 GLN B OE1 1 ATOM 186 N NE2 . GLN A 1 25 ? 68.993 84.919 -45.724 1.00 88.98 ? 85 GLN B NE2 1 ATOM 187 N N . GLY A 1 26 ? 69.212 79.775 -44.276 1.00 85.88 ? 86 GLY B N 1 ATOM 188 C CA . GLY A 1 26 ? 69.450 78.412 -44.737 1.00 84.67 ? 86 GLY B CA 1 ATOM 189 C C . GLY A 1 26 ? 68.402 77.338 -44.488 1.00 80.00 ? 86 GLY B C 1 ATOM 190 O O . GLY A 1 26 ? 67.323 77.610 -43.971 1.00 84.47 ? 86 GLY B O 1 ATOM 191 N N . SER A 1 27 ? 68.744 76.106 -44.861 1.00 73.73 ? 87 SER B N 1 ATOM 192 C CA . SER A 1 27 ? 67.861 74.946 -44.735 1.00 71.08 ? 87 SER B CA 1 ATOM 193 C C . SER A 1 27 ? 67.877 74.351 -43.335 1.00 82.12 ? 87 SER B C 1 ATOM 194 O O . SER A 1 27 ? 68.366 74.969 -42.393 1.00 89.40 ? 87 SER B O 1 ATOM 195 C CB . SER A 1 27 ? 68.234 73.863 -45.746 1.00 63.35 ? 87 SER B CB 1 ATOM 196 O OG . SER A 1 27 ? 68.012 74.302 -47.070 1.00 60.10 ? 87 SER B OG 1 ATOM 197 N N . LEU A 1 28 ? 67.322 73.150 -43.206 1.00 84.79 ? 88 LEU B N 1 ATOM 198 C CA . LEU A 1 28 ? 67.198 72.502 -41.905 1.00 87.20 ? 88 LEU B CA 1 ATOM 199 C C . LEU A 1 28 ? 67.236 70.980 -42.021 1.00 86.98 ? 88 LEU B C 1 ATOM 200 O O . LEU A 1 28 ? 67.094 70.431 -43.113 1.00 85.11 ? 88 LEU B O 1 ATOM 201 C CB . LEU A 1 28 ? 65.912 72.959 -41.201 1.00 84.73 ? 88 LEU B CB 1 ATOM 202 C CG . LEU A 1 28 ? 64.553 72.768 -41.889 1.00 79.29 ? 88 LEU B CG 1 ATOM 203 C CD1 . LEU A 1 28 ? 63.445 72.924 -40.871 1.00 72.25 ? 88 LEU B CD1 1 ATOM 204 C CD2 . LEU A 1 28 ? 64.328 73.740 -43.044 1.00 81.53 ? 88 LEU B CD2 1 ATOM 205 N N . LEU A 1 36 ? 67.092 61.533 -33.079 1.00 54.91 ? 92 LEU B N 1 ATOM 206 C CA . LEU A 1 36 ? 66.215 61.638 -31.917 1.00 55.87 ? 92 LEU B CA 1 ATOM 207 C C . LEU A 1 36 ? 64.779 61.293 -32.297 1.00 56.25 ? 92 LEU B C 1 ATOM 208 O O . LEU A 1 36 ? 63.969 62.158 -32.622 1.00 49.41 ? 92 LEU B O 1 ATOM 209 C CB . LEU A 1 36 ? 66.315 63.029 -31.274 1.00 53.27 ? 92 LEU B CB 1 ATOM 210 C CG . LEU A 1 36 ? 66.421 64.261 -32.180 1.00 45.64 ? 92 LEU B CG 1 ATOM 211 C CD1 . LEU A 1 36 ? 65.120 65.002 -32.210 1.00 50.97 ? 92 LEU B CD1 1 ATOM 212 C CD2 . LEU A 1 36 ? 67.516 65.194 -31.721 1.00 41.65 ? 92 LEU B CD2 1 ATOM 213 N N . LYS A 1 37 ? 64.470 60.007 -32.244 1.00 63.23 ? 93 LYS B N 1 ATOM 214 C CA . LYS A 1 37 ? 63.233 59.501 -32.814 1.00 64.89 ? 93 LYS B CA 1 ATOM 215 C C . LYS A 1 37 ? 62.077 59.477 -31.806 1.00 58.91 ? 93 LYS B C 1 ATOM 216 O O . LYS A 1 37 ? 61.016 58.904 -32.068 1.00 58.14 ? 93 LYS B O 1 ATOM 217 C CB . LYS A 1 37 ? 63.486 58.164 -33.523 1.00 69.37 ? 93 LYS B CB 1 ATOM 218 C CG . LYS A 1 37 ? 64.527 58.314 -34.653 1.00 74.46 ? 93 LYS B CG 1 ATOM 219 C CD . LYS A 1 37 ? 65.020 56.992 -35.232 1.00 77.86 ? 93 LYS B CD 1 ATOM 220 C CE . LYS A 1 37 ? 63.996 56.365 -36.172 1.00 78.45 ? 93 LYS B CE 1 ATOM 221 N NZ . LYS A 1 37 ? 64.549 55.182 -36.900 1.00 78.53 ? 93 LYS B NZ 1 ATOM 222 N N . SER A 1 38 ? 62.308 60.080 -30.641 1.00 51.32 ? 94 SER B N 1 ATOM 223 C CA . SER A 1 38 ? 61.283 60.214 -29.601 1.00 50.93 ? 94 SER B CA 1 ATOM 224 C C . SER A 1 38 ? 60.524 61.558 -29.623 1.00 50.48 ? 94 SER B C 1 ATOM 225 O O . SER A 1 38 ? 59.702 61.832 -28.740 1.00 46.74 ? 94 SER B O 1 ATOM 226 C CB . SER A 1 38 ? 61.910 59.999 -28.222 1.00 50.17 ? 94 SER B CB 1 ATOM 227 O OG . SER A 1 38 ? 62.965 60.923 -28.019 1.00 51.85 ? 94 SER B OG 1 ATOM 228 N N . LEU A 1 39 ? 60.810 62.389 -30.622 1.00 47.78 ? 95 LEU B N 1 ATOM 229 C CA . LEU A 1 39 ? 60.271 63.748 -30.707 1.00 41.51 ? 95 LEU B CA 1 ATOM 230 C C . LEU A 1 39 ? 58.750 63.848 -30.752 1.00 44.40 ? 95 LEU B C 1 ATOM 231 O O . LEU A 1 39 ? 58.078 63.035 -31.378 1.00 50.02 ? 95 LEU B O 1 ATOM 232 C CB . LEU A 1 39 ? 60.846 64.465 -31.922 1.00 38.71 ? 95 LEU B CB 1 ATOM 233 C CG . LEU A 1 39 ? 60.924 65.976 -31.759 1.00 38.78 ? 95 LEU B CG 1 ATOM 234 C CD1 . LEU A 1 39 ? 61.505 66.307 -30.395 1.00 40.54 ? 95 LEU B CD1 1 ATOM 235 C CD2 . LEU A 1 39 ? 61.787 66.554 -32.864 1.00 43.67 ? 95 LEU B CD2 1 ATOM 236 N N . THR A 1 40 ? 58.232 64.886 -30.105 1.00 40.00 ? 96 THR B N 1 ATOM 237 C CA . THR A 1 40 ? 56.797 65.119 -29.953 1.00 34.91 ? 96 THR B CA 1 ATOM 238 C C . THR A 1 40 ? 56.371 66.472 -30.539 1.00 36.49 ? 96 THR B C 1 ATOM 239 O O . THR A 1 40 ? 55.468 66.544 -31.372 1.00 37.40 ? 96 THR B O 1 ATOM 240 C CB . THR A 1 40 ? 56.353 64.986 -28.482 1.00 39.03 ? 96 THR B CB 1 ATOM 241 O OG1 . THR A 1 40 ? 56.168 63.601 -28.170 1.00 36.68 ? 96 THR B OG1 1 ATOM 242 C CG2 . THR A 1 40 ? 55.044 65.717 -28.240 1.00 46.09 ? 96 THR B CG2 1 ATOM 243 N N . SER A 1 41 ? 56.968 67.548 -30.043 1.00 28.11 ? 97 SER B N 1 ATOM 244 C CA . SER A 1 41 ? 56.679 68.878 -30.550 1.00 40.43 ? 97 SER B CA 1 ATOM 245 C C . SER A 1 41 ? 57.907 69.509 -31.202 1.00 41.03 ? 97 SER B C 1 ATOM 246 O O . SER A 1 41 ? 58.983 69.536 -30.615 1.00 42.24 ? 97 SER B O 1 ATOM 247 C CB . SER A 1 41 ? 56.143 69.775 -29.430 1.00 40.04 ? 97 SER B CB 1 ATOM 248 O OG . SER A 1 41 ? 56.433 71.140 -29.684 1.00 42.92 ? 97 SER B OG 1 ATOM 249 N N . LEU A 1 42 ? 57.746 70.011 -32.421 1.00 27.81 ? 98 LEU B N 1 ATOM 250 C CA . LEU A 1 42 ? 58.846 70.678 -33.098 1.00 36.83 ? 98 LEU B CA 1 ATOM 251 C C . LEU A 1 42 ? 58.451 72.051 -33.631 1.00 35.99 ? 98 LEU B C 1 ATOM 252 O O . LEU A 1 42 ? 57.670 72.152 -34.573 1.00 35.40 ? 98 LEU B O 1 ATOM 253 C CB . LEU A 1 42 ? 59.354 69.807 -34.245 1.00 29.22 ? 98 LEU B CB 1 ATOM 254 C CG . LEU A 1 42 ? 60.410 70.444 -35.150 1.00 32.64 ? 98 LEU B CG 1 ATOM 255 C CD1 . LEU A 1 42 ? 61.706 70.671 -34.383 1.00 31.19 ? 98 LEU B CD1 1 ATOM 256 C CD2 . LEU A 1 42 ? 60.658 69.583 -36.389 1.00 30.38 ? 98 LEU B CD2 1 ATOM 257 N N . THR A 1 43 ? 59.009 73.103 -33.039 1.00 27.99 ? 99 THR B N 1 ATOM 258 C CA . THR A 1 43 ? 58.779 74.458 -33.520 1.00 27.33 ? 99 THR B CA 1 ATOM 259 C C . THR A 1 43 ? 60.059 75.112 -34.020 1.00 34.33 ? 99 THR B C 1 ATOM 260 O O . THR A 1 43 ? 60.971 75.396 -33.245 1.00 35.88 ? 99 THR B O 1 ATOM 261 C CB . THR A 1 43 ? 58.148 75.365 -32.439 1.00 39.67 ? 99 THR B CB 1 ATOM 262 O OG1 . THR A 1 43 ? 56.804 74.947 -32.179 1.00 41.87 ? 99 THR B OG1 1 ATOM 263 C CG2 . THR A 1 43 ? 58.113 76.813 -32.911 1.00 26.13 ? 99 THR B CG2 1 ATOM 264 N N . LEU A 1 44 ? 60.137 75.315 -35.329 1.00 36.89 ? 100 LEU B N 1 ATOM 265 C CA . LEU A 1 44 ? 61.127 76.219 -35.895 1.00 38.10 ? 100 LEU B CA 1 ATOM 266 C C . LEU A 1 44 ? 60.375 77.350 -36.584 1.00 37.69 ? 100 LEU B C 1 ATOM 267 O O . LEU A 1 44 ? 59.869 77.187 -37.691 1.00 36.67 ? 100 LEU B O 1 ATOM 268 C CB . LEU A 1 44 ? 62.008 75.460 -36.877 1.00 29.82 ? 100 LEU B CB 1 ATOM 269 C CG . LEU A 1 44 ? 62.666 74.237 -36.229 1.00 34.60 ? 100 LEU B CG 1 ATOM 270 C CD1 . LEU A 1 44 ? 63.402 73.415 -37.247 1.00 33.94 ? 100 LEU B CD1 1 ATOM 271 C CD2 . LEU A 1 44 ? 63.615 74.659 -35.108 1.00 40.19 ? 100 LEU B CD2 1 ATOM 272 N N . SER A 1 45 ? 60.357 78.517 -35.952 1.00 41.10 ? 101 SER B N 1 ATOM 273 C CA . SER A 1 45 ? 59.434 79.570 -36.346 1.00 41.67 ? 101 SER B CA 1 ATOM 274 C C . SER A 1 45 ? 60.052 80.955 -36.225 1.00 45.25 ? 101 SER B C 1 ATOM 275 O O . SER A 1 45 ? 60.757 81.249 -35.258 1.00 44.27 ? 101 SER B O 1 ATOM 276 C CB . SER A 1 45 ? 58.170 79.501 -35.486 1.00 45.74 ? 101 SER B CB 1 ATOM 277 O OG . SER A 1 45 ? 57.320 80.608 -35.737 1.00 51.74 ? 101 SER B OG 1 ATOM 278 N N . SER A 1 46 ? 59.764 81.801 -37.211 1.00 44.78 ? 102 SER B N 1 ATOM 279 C CA . SER A 1 46 ? 60.269 83.166 -37.244 1.00 41.30 ? 102 SER B CA 1 ATOM 280 C C . SER A 1 46 ? 61.799 83.198 -37.247 1.00 43.51 ? 102 SER B C 1 ATOM 281 O O . SER A 1 46 ? 62.410 84.071 -36.636 1.00 46.84 ? 102 SER B O 1 ATOM 282 C CB . SER A 1 46 ? 59.695 83.968 -36.079 1.00 41.12 ? 102 SER B CB 1 ATOM 283 O OG . SER A 1 46 ? 58.303 83.709 -35.939 1.00 39.03 ? 102 SER B OG 1 ATOM 284 N N . LEU A 1 47 ? 62.404 82.215 -37.913 1.00 38.69 ? 103 LEU B N 1 ATOM 285 C CA . LEU A 1 47 ? 63.857 82.132 -38.047 1.00 42.19 ? 103 LEU B CA 1 ATOM 286 C C . LEU A 1 47 ? 64.411 82.607 -39.388 1.00 49.65 ? 103 LEU B C 1 ATOM 287 O O . LEU A 1 47 ? 65.605 82.490 -39.637 1.00 52.47 ? 103 LEU B O 1 ATOM 288 C CB . LEU A 1 47 ? 64.325 80.709 -37.774 1.00 41.45 ? 103 LEU B CB 1 ATOM 289 C CG . LEU A 1 47 ? 63.663 80.086 -36.549 1.00 38.09 ? 103 LEU B CG 1 ATOM 290 C CD1 . LEU A 1 47 ? 64.041 78.631 -36.454 1.00 33.11 ? 103 LEU B CD1 1 ATOM 291 C CD2 . LEU A 1 47 ? 64.048 80.837 -35.279 1.00 42.93 ? 103 LEU B CD2 1 ATOM 292 N N . GLN A 1 48 ? 63.540 83.092 -40.266 1.00 54.85 ? 104 GLN B N 1 ATOM 293 C CA . GLN A 1 48 ? 63.941 83.497 -41.615 1.00 49.79 ? 104 GLN B CA 1 ATOM 294 C C . GLN A 1 48 ? 64.652 82.375 -42.396 1.00 46.68 ? 104 GLN B C 1 ATOM 295 O O . GLN A 1 48 ? 65.567 82.640 -43.178 1.00 48.27 ? 104 GLN B O 1 ATOM 296 C CB . GLN A 1 48 ? 64.798 84.773 -41.575 1.00 45.26 ? 104 GLN B CB 1 ATOM 297 N N . LEU A 1 49 ? 64.217 81.133 -42.189 1.00 38.07 ? 105 LEU B N 1 ATOM 298 C CA . LEU A 1 49 ? 64.794 79.975 -42.879 1.00 34.26 ? 105 LEU B CA 1 ATOM 299 C C . LEU A 1 49 ? 64.455 79.953 -44.369 1.00 38.69 ? 105 LEU B C 1 ATOM 300 O O . LEU A 1 49 ? 63.495 80.580 -44.806 1.00 40.93 ? 105 LEU B O 1 ATOM 301 C CB . LEU A 1 49 ? 64.309 78.669 -42.241 1.00 32.60 ? 105 LEU B CB 1 ATOM 302 C CG . LEU A 1 49 ? 64.437 78.498 -40.721 1.00 39.61 ? 105 LEU B CG 1 ATOM 303 C CD1 . LEU A 1 49 ? 63.768 77.198 -40.252 1.00 36.72 ? 105 LEU B CD1 1 ATOM 304 C CD2 . LEU A 1 49 ? 65.893 78.542 -40.282 1.00 40.53 ? 105 LEU B CD2 1 ATOM 305 N N . THR A 1 50 ? 65.247 79.228 -45.151 1.00 41.88 ? 106 THR B N 1 ATOM 306 C CA . THR A 1 50 ? 64.976 79.093 -46.581 1.00 44.73 ? 106 THR B CA 1 ATOM 307 C C . THR A 1 50 ? 65.135 77.647 -47.036 1.00 41.61 ? 106 THR B C 1 ATOM 308 O O . THR A 1 50 ? 65.504 76.773 -46.246 1.00 32.35 ? 106 THR B O 1 ATOM 309 C CB . THR A 1 50 ? 65.875 80.023 -47.456 1.00 46.91 ? 106 THR B CB 1 ATOM 310 O OG1 . THR A 1 50 ? 67.248 79.887 -47.066 1.00 53.89 ? 106 THR B OG1 1 ATOM 311 C CG2 . THR A 1 50 ? 65.460 81.480 -47.304 1.00 39.72 ? 106 THR B CG2 1 ATOM 312 N N . GLY A 1 51 ? 64.863 77.406 -48.315 1.00 34.85 ? 107 GLY B N 1 ATOM 313 C CA . GLY A 1 51 ? 64.915 76.064 -48.861 1.00 40.86 ? 107 GLY B CA 1 ATOM 314 C C . GLY A 1 51 ? 63.600 75.325 -48.724 1.00 48.56 ? 107 GLY B C 1 ATOM 315 O O . GLY A 1 51 ? 62.611 75.883 -48.252 1.00 53.77 ? 107 GLY B O 1 ATOM 316 N N . VAL A 1 52 ? 63.588 74.074 -49.176 1.00 52.19 ? 108 VAL B N 1 ATOM 317 C CA . VAL A 1 52 ? 62.452 73.173 -49.006 1.00 30.52 ? 108 VAL B CA 1 ATOM 318 C C . VAL A 1 52 ? 62.378 72.597 -47.597 1.00 37.08 ? 108 VAL B C 1 ATOM 319 O O . VAL A 1 52 ? 63.368 72.598 -46.859 1.00 31.59 ? 108 VAL B O 1 ATOM 320 C CB . VAL A 1 52 ? 62.527 71.973 -49.977 1.00 33.44 ? 108 VAL B CB 1 ATOM 321 C CG1 . VAL A 1 52 ? 62.423 72.436 -51.421 1.00 30.79 ? 108 VAL B CG1 1 ATOM 322 C CG2 . VAL A 1 52 ? 63.807 71.155 -49.731 1.00 32.52 ? 108 VAL B CG2 1 ATOM 323 N N . ILE A 1 53 ? 61.186 72.121 -47.234 1.00 35.11 ? 109 ILE B N 1 ATOM 324 C CA . ILE A 1 53 ? 60.986 71.276 -46.064 1.00 29.79 ? 109 ILE B CA 1 ATOM 325 C C . ILE A 1 53 ? 61.519 69.894 -46.390 1.00 42.36 ? 109 ILE B C 1 ATOM 326 O O . ILE A 1 53 ? 61.038 69.254 -47.329 1.00 45.63 ? 109 ILE B O 1 ATOM 327 C CB . ILE A 1 53 ? 59.490 71.108 -45.756 1.00 28.48 ? 109 ILE B CB 1 ATOM 328 C CG1 . ILE A 1 53 ? 58.891 72.421 -45.236 1.00 27.50 ? 109 ILE B CG1 1 ATOM 329 C CG2 . ILE A 1 53 ? 59.271 69.958 -44.781 1.00 28.68 ? 109 ILE B CG2 1 ATOM 330 C CD1 . ILE A 1 53 ? 57.383 72.492 -45.340 1.00 26.14 ? 109 ILE B CD1 1 ATOM 331 N N . PRO A 1 54 ? 62.507 69.420 -45.614 1.00 38.60 ? 110 PRO B N 1 ATOM 332 C CA . PRO A 1 54 ? 63.111 68.112 -45.888 1.00 36.82 ? 110 PRO B CA 1 ATOM 333 C C . PRO A 1 54 ? 62.040 67.050 -45.714 1.00 43.35 ? 110 PRO B C 1 ATOM 334 O O . PRO A 1 54 ? 61.256 67.183 -44.777 1.00 58.58 ? 110 PRO B O 1 ATOM 335 C CB . PRO A 1 54 ? 64.166 67.972 -44.782 1.00 34.01 ? 110 PRO B CB 1 ATOM 336 C CG . PRO A 1 54 ? 64.311 69.339 -44.166 1.00 33.67 ? 110 PRO B CG 1 ATOM 337 C CD . PRO A 1 54 ? 62.992 70.007 -44.354 1.00 36.71 ? 110 PRO B CD 1 ATOM 338 N N . LYS A 1 55 ? 61.988 66.023 -46.557 1.00 38.82 ? 111 LYS B N 1 ATOM 339 C CA . LYS A 1 55 ? 60.909 65.046 -46.411 1.00 43.71 ? 111 LYS B CA 1 ATOM 340 C C . LYS A 1 55 ? 61.177 63.972 -45.357 1.00 48.56 ? 111 LYS B C 1 ATOM 341 O O . LYS A 1 55 ? 60.381 63.047 -45.177 1.00 47.25 ? 111 LYS B O 1 ATOM 342 C CB . LYS A 1 55 ? 60.441 64.443 -47.745 1.00 47.88 ? 111 LYS B CB 1 ATOM 343 C CG . LYS A 1 55 ? 61.458 64.275 -48.867 1.00 39.98 ? 111 LYS B CG 1 ATOM 344 C CD . LYS A 1 55 ? 60.683 63.900 -50.134 1.00 36.36 ? 111 LYS B CD 1 ATOM 345 C CE . LYS A 1 55 ? 61.534 63.902 -51.389 1.00 42.80 ? 111 LYS B CE 1 ATOM 346 N NZ . LYS A 1 55 ? 62.377 62.673 -51.476 1.00 52.62 ? 111 LYS B NZ 1 ATOM 347 N N . GLU A 1 56 ? 62.300 64.110 -44.658 1.00 49.84 ? 112 GLU B N 1 ATOM 348 C CA . GLU A 1 56 ? 62.621 63.225 -43.550 1.00 50.62 ? 112 GLU B CA 1 ATOM 349 C C . GLU A 1 56 ? 61.808 63.575 -42.300 1.00 52.17 ? 112 GLU B C 1 ATOM 350 O O . GLU A 1 56 ? 61.828 62.844 -41.306 1.00 54.73 ? 112 GLU B O 1 ATOM 351 C CB . GLU A 1 56 ? 64.123 63.249 -43.255 1.00 56.87 ? 112 GLU B CB 1 ATOM 352 C CG . GLU A 1 56 ? 64.986 62.657 -44.371 1.00 63.44 ? 112 GLU B CG 1 ATOM 353 C CD . GLU A 1 56 ? 65.357 63.679 -45.432 1.00 72.03 ? 112 GLU B CD 1 ATOM 354 O OE1 . GLU A 1 56 ? 66.179 64.571 -45.128 1.00 78.73 ? 112 GLU B OE1 1 ATOM 355 O OE2 . GLU A 1 56 ? 64.832 63.592 -46.566 1.00 69.97 ? 112 GLU B OE2 1 ATOM 356 N N . ILE A 1 57 ? 61.093 64.695 -42.359 1.00 45.69 ? 113 ILE B N 1 ATOM 357 C CA . ILE A 1 57 ? 60.165 65.087 -41.301 1.00 36.12 ? 113 ILE B CA 1 ATOM 358 C C . ILE A 1 57 ? 59.145 63.982 -41.042 1.00 37.41 ? 113 ILE B C 1 ATOM 359 O O . ILE A 1 57 ? 58.743 63.746 -39.905 1.00 47.22 ? 113 ILE B O 1 ATOM 360 C CB . ILE A 1 57 ? 59.438 66.396 -41.678 1.00 40.87 ? 113 ILE B CB 1 ATOM 361 C CG1 . ILE A 1 57 ? 60.358 67.596 -41.460 1.00 45.70 ? 113 ILE B CG1 1 ATOM 362 C CG2 . ILE A 1 57 ? 58.177 66.591 -40.859 1.00 37.50 ? 113 ILE B CG2 1 ATOM 363 C CD1 . ILE A 1 57 ? 60.432 68.059 -40.019 1.00 41.79 ? 113 ILE B CD1 1 ATOM 364 N N . GLY A 1 58 ? 58.754 63.277 -42.096 1.00 30.71 ? 114 GLY B N 1 ATOM 365 C CA . GLY A 1 58 ? 57.794 62.197 -41.982 1.00 34.58 ? 114 GLY B CA 1 ATOM 366 C C . GLY A 1 58 ? 58.335 60.989 -41.240 1.00 44.07 ? 114 GLY B C 1 ATOM 367 O O . GLY A 1 58 ? 57.630 59.992 -41.083 1.00 48.58 ? 114 GLY B O 1 ATOM 368 N N . ASP A 1 59 ? 59.588 61.060 -40.795 1.00 51.05 ? 115 ASP B N 1 ATOM 369 C CA . ASP A 1 59 ? 60.157 59.991 -39.969 1.00 53.99 ? 115 ASP B CA 1 ATOM 370 C C . ASP A 1 59 ? 59.899 60.130 -38.462 1.00 51.51 ? 115 ASP B C 1 ATOM 371 O O . ASP A 1 59 ? 60.013 59.144 -37.733 1.00 51.25 ? 115 ASP B O 1 ATOM 372 C CB . ASP A 1 59 ? 61.666 59.823 -40.215 1.00 54.40 ? 115 ASP B CB 1 ATOM 373 C CG . ASP A 1 59 ? 61.994 59.387 -41.638 1.00 55.98 ? 115 ASP B CG 1 ATOM 374 O OD1 . ASP A 1 59 ? 61.101 58.859 -42.343 1.00 54.06 ? 115 ASP B OD1 1 ATOM 375 O OD2 . ASP A 1 59 ? 63.165 59.569 -42.045 1.00 58.96 ? 115 ASP B OD2 1 ATOM 376 N N . PHE A 1 60 ? 59.514 61.315 -37.983 1.00 51.21 ? 116 PHE B N 1 ATOM 377 C CA . PHE A 1 60 ? 59.345 61.458 -36.538 1.00 44.11 ? 116 PHE B CA 1 ATOM 378 C C . PHE A 1 60 ? 57.913 61.078 -36.242 1.00 46.28 ? 116 PHE B C 1 ATOM 379 O O . PHE A 1 60 ? 57.009 61.899 -36.338 1.00 44.83 ? 116 PHE B O 1 ATOM 380 C CB . PHE A 1 60 ? 59.534 62.915 -36.101 1.00 35.21 ? 116 PHE B CB 1 ATOM 381 C CG . PHE A 1 60 ? 60.909 63.473 -36.363 1.00 39.98 ? 116 PHE B CG 1 ATOM 382 C CD1 . PHE A 1 60 ? 62.007 63.025 -35.646 1.00 41.49 ? 116 PHE B CD1 1 ATOM 383 C CD2 . PHE A 1 60 ? 61.094 64.488 -37.294 1.00 39.80 ? 116 PHE B CD2 1 ATOM 384 C CE1 . PHE A 1 60 ? 63.272 63.555 -35.877 1.00 42.22 ? 116 PHE B CE1 1 ATOM 385 C CE2 . PHE A 1 60 ? 62.356 65.022 -37.525 1.00 37.54 ? 116 PHE B CE2 1 ATOM 386 C CZ . PHE A 1 60 ? 63.444 64.552 -36.820 1.00 38.15 ? 116 PHE B CZ 1 ATOM 387 N N . THR A 1 61 ? 57.725 59.863 -35.749 1.00 50.60 ? 117 THR B N 1 ATOM 388 C CA . THR A 1 61 ? 56.395 59.278 -35.736 1.00 52.40 ? 117 THR B CA 1 ATOM 389 C C . THR A 1 61 ? 55.587 59.797 -34.567 1.00 52.52 ? 117 THR B C 1 ATOM 390 O O . THR A 1 61 ? 54.363 59.755 -34.584 1.00 61.64 ? 117 THR B O 1 ATOM 391 C CB . THR A 1 61 ? 56.458 57.746 -35.665 1.00 56.72 ? 117 THR B CB 1 ATOM 392 O OG1 . THR A 1 61 ? 57.640 57.280 -36.328 1.00 48.33 ? 117 THR B OG1 1 ATOM 393 C CG2 . THR A 1 61 ? 55.222 57.139 -36.325 1.00 65.13 ? 117 THR B CG2 1 ATOM 394 N N . GLU A 1 62 ? 56.278 60.299 -33.553 1.00 43.64 ? 118 GLU B N 1 ATOM 395 C CA . GLU A 1 62 ? 55.608 60.743 -32.346 1.00 42.86 ? 118 GLU B CA 1 ATOM 396 C C . GLU A 1 62 ? 55.290 62.232 -32.386 1.00 38.78 ? 118 GLU B C 1 ATOM 397 O O . GLU A 1 62 ? 54.766 62.785 -31.417 1.00 42.23 ? 118 GLU B O 1 ATOM 398 C CB . GLU A 1 62 ? 56.447 60.391 -31.103 1.00 48.21 ? 118 GLU B CB 1 ATOM 399 C CG . GLU A 1 62 ? 55.903 59.211 -30.304 1.00 48.47 ? 118 GLU B CG 1 ATOM 400 C CD . GLU A 1 62 ? 55.548 58.034 -31.193 1.00 53.19 ? 118 GLU B CD 1 ATOM 401 O OE1 . GLU A 1 62 ? 56.427 57.578 -31.954 1.00 56.03 ? 118 GLU B OE1 1 ATOM 402 O OE2 . GLU A 1 62 ? 54.389 57.572 -31.148 1.00 53.98 ? 118 GLU B OE2 1 ATOM 403 N N . LEU A 1 63 ? 55.614 62.882 -33.499 1.00 34.95 ? 119 LEU B N 1 ATOM 404 C CA . LEU A 1 63 ? 55.332 64.305 -33.644 1.00 33.32 ? 119 LEU B CA 1 ATOM 405 C C . LEU A 1 63 ? 53.830 64.564 -33.513 1.00 29.38 ? 119 LEU B C 1 ATOM 406 O O . LEU A 1 63 ? 53.024 63.971 -34.236 1.00 25.61 ? 119 LEU B O 1 ATOM 407 C CB . LEU A 1 63 ? 55.826 64.785 -35.005 1.00 34.85 ? 119 LEU B CB 1 ATOM 408 C CG . LEU A 1 63 ? 56.531 66.133 -35.061 1.00 33.13 ? 119 LEU B CG 1 ATOM 409 C CD1 . LEU A 1 63 ? 57.443 66.302 -33.861 1.00 28.66 ? 119 LEU B CD1 1 ATOM 410 C CD2 . LEU A 1 63 ? 57.321 66.211 -36.361 1.00 28.98 ? 119 LEU B CD2 1 ATOM 411 N N . GLU A 1 64 ? 53.451 65.386 -32.538 1.00 26.99 ? 120 GLU B N 1 ATOM 412 C CA . GLU A 1 64 ? 52.077 65.876 -32.443 1.00 28.17 ? 120 GLU B CA 1 ATOM 413 C C . GLU A 1 64 ? 51.928 67.343 -32.835 1.00 23.56 ? 120 GLU B C 1 ATOM 414 O O . GLU A 1 64 ? 50.805 67.845 -32.994 1.00 22.47 ? 120 GLU B O 1 ATOM 415 C CB . GLU A 1 64 ? 51.555 65.668 -31.015 1.00 29.02 ? 120 GLU B CB 1 ATOM 416 C CG . GLU A 1 64 ? 51.393 64.205 -30.619 1.00 37.33 ? 120 GLU B CG 1 ATOM 417 C CD . GLU A 1 64 ? 51.794 63.934 -29.171 1.00 47.02 ? 120 GLU B CD 1 ATOM 418 O OE1 . GLU A 1 64 ? 51.922 64.907 -28.396 1.00 50.40 ? 120 GLU B OE1 1 ATOM 419 O OE2 . GLU A 1 64 ? 51.994 62.748 -28.811 1.00 47.03 ? 120 GLU B OE2 1 ATOM 420 N N . LEU A 1 65 ? 53.063 68.028 -32.970 1.00 24.27 ? 121 LEU B N 1 ATOM 421 C CA . LEU A 1 65 ? 53.083 69.435 -33.349 1.00 23.81 ? 121 LEU B CA 1 ATOM 422 C C . LEU A 1 65 ? 54.263 69.745 -34.247 1.00 31.33 ? 121 LEU B C 1 ATOM 423 O O . LEU A 1 65 ? 55.411 69.495 -33.885 1.00 32.54 ? 121 LEU B O 1 ATOM 424 C CB . LEU A 1 65 ? 53.121 70.347 -32.128 1.00 23.63 ? 121 LEU B CB 1 ATOM 425 C CG . LEU A 1 65 ? 53.043 71.856 -32.417 1.00 33.16 ? 121 LEU B CG 1 ATOM 426 C CD1 . LEU A 1 65 ? 52.135 72.561 -31.422 1.00 33.09 ? 121 LEU B CD1 1 ATOM 427 C CD2 . LEU A 1 65 ? 54.408 72.520 -32.397 1.00 33.97 ? 121 LEU B CD2 1 ATOM 428 N N . LEU A 1 66 ? 53.967 70.331 -35.399 1.00 26.62 ? 122 LEU B N 1 ATOM 429 C CA . LEU A 1 66 ? 54.981 70.817 -36.308 1.00 27.83 ? 122 LEU B CA 1 ATOM 430 C C . LEU A 1 66 ? 54.642 72.267 -36.634 1.00 28.33 ? 122 LEU B C 1 ATOM 431 O O . LEU A 1 66 ? 53.626 72.548 -37.267 1.00 23.08 ? 122 LEU B O 1 ATOM 432 C CB . LEU A 1 66 ? 54.968 69.980 -37.592 1.00 28.86 ? 122 LEU B CB 1 ATOM 433 C CG . LEU A 1 66 ? 56.052 70.290 -38.623 1.00 27.82 ? 122 LEU B CG 1 ATOM 434 C CD1 . LEU A 1 66 ? 57.399 69.887 -38.048 1.00 27.17 ? 122 LEU B CD1 1 ATOM 435 C CD2 . LEU A 1 66 ? 55.767 69.571 -39.937 1.00 25.78 ? 122 LEU B CD2 1 ATOM 436 N N . ASP A 1 67 ? 55.469 73.197 -36.177 1.00 31.90 ? 123 ASP B N 1 ATOM 437 C CA . ASP A 1 67 ? 55.242 74.587 -36.523 1.00 32.15 ? 123 ASP B CA 1 ATOM 438 C C . ASP A 1 67 ? 56.465 75.095 -37.244 1.00 36.74 ? 123 ASP B C 1 ATOM 439 O O . ASP A 1 67 ? 57.527 75.280 -36.645 1.00 36.58 ? 123 ASP B O 1 ATOM 440 C CB . ASP A 1 67 ? 54.950 75.427 -35.282 1.00 23.47 ? 123 ASP B CB 1 ATOM 441 C CG . ASP A 1 67 ? 54.734 76.895 -35.602 1.00 34.71 ? 123 ASP B CG 1 ATOM 442 O OD1 . ASP A 1 67 ? 54.787 77.283 -36.787 1.00 37.30 ? 123 ASP B OD1 1 ATOM 443 O OD2 . ASP A 1 67 ? 54.500 77.677 -34.661 1.00 39.87 ? 123 ASP B OD2 1 ATOM 444 N N . LEU A 1 68 ? 56.291 75.274 -38.549 1.00 35.30 ? 124 LEU B N 1 ATOM 445 C CA . LEU A 1 68 ? 57.269 75.875 -39.430 1.00 30.57 ? 124 LEU B CA 1 ATOM 446 C C . LEU A 1 68 ? 56.941 77.321 -39.810 1.00 33.34 ? 124 LEU B C 1 ATOM 447 O O . LEU A 1 68 ? 57.567 77.889 -40.716 1.00 31.36 ? 124 LEU B O 1 ATOM 448 C CB . LEU A 1 68 ? 57.528 74.973 -40.634 1.00 30.27 ? 124 LEU B CB 1 ATOM 449 C CG . LEU A 1 68 ? 58.032 73.599 -40.148 1.00 35.32 ? 124 LEU B CG 1 ATOM 450 C CD1 . LEU A 1 68 ? 58.414 72.674 -41.309 1.00 32.62 ? 124 LEU B CD1 1 ATOM 451 C CD2 . LEU A 1 68 ? 59.186 73.723 -39.145 1.00 27.52 ? 124 LEU B CD2 1 ATOM 452 N N . SER A 1 69 ? 55.929 77.894 -39.157 1.00 26.62 ? 125 SER B N 1 ATOM 453 C CA . SER A 1 69 ? 55.367 79.175 -39.601 1.00 29.76 ? 125 SER B CA 1 ATOM 454 C C . SER A 1 69 ? 56.324 80.355 -39.512 1.00 34.16 ? 125 SER B C 1 ATOM 455 O O . SER A 1 69 ? 57.348 80.292 -38.832 1.00 34.64 ? 125 SER B O 1 ATOM 456 C CB . SER A 1 69 ? 54.080 79.515 -38.856 1.00 27.21 ? 125 SER B CB 1 ATOM 457 O OG . SER A 1 69 ? 54.360 79.825 -37.504 1.00 32.08 ? 125 SER B OG 1 ATOM 458 N N . ASP A 1 70 ? 55.978 81.413 -40.245 1.00 40.97 ? 126 ASP B N 1 ATOM 459 C CA . ASP A 1 70 ? 56.736 82.669 -40.294 1.00 40.18 ? 126 ASP B CA 1 ATOM 460 C C . ASP A 1 70 ? 58.195 82.471 -40.716 1.00 39.21 ? 126 ASP B C 1 ATOM 461 O O . ASP A 1 70 ? 59.121 82.972 -40.081 1.00 39.62 ? 126 ASP B O 1 ATOM 462 C CB . ASP A 1 70 ? 56.632 83.436 -38.970 1.00 34.74 ? 126 ASP B CB 1 ATOM 463 C CG . ASP A 1 70 ? 57.136 84.874 -39.079 1.00 38.52 ? 126 ASP B CG 1 ATOM 464 O OD1 . ASP A 1 70 ? 57.011 85.484 -40.165 1.00 32.14 ? 126 ASP B OD1 1 ATOM 465 O OD2 . ASP A 1 70 ? 57.660 85.394 -38.066 1.00 48.76 ? 126 ASP B OD2 1 ATOM 466 N N . ASN A 1 71 ? 58.383 81.726 -41.796 1.00 33.78 ? 127 ASN B N 1 ATOM 467 C CA . ASN A 1 71 ? 59.694 81.580 -42.402 1.00 34.25 ? 127 ASN B CA 1 ATOM 468 C C . ASN A 1 71 ? 59.635 81.961 -43.872 1.00 37.38 ? 127 ASN B C 1 ATOM 469 O O . ASN A 1 71 ? 58.623 82.472 -44.360 1.00 37.09 ? 127 ASN B O 1 ATOM 470 C CB . ASN A 1 71 ? 60.196 80.144 -42.270 1.00 32.77 ? 127 ASN B CB 1 ATOM 471 C CG . ASN A 1 71 ? 60.791 79.864 -40.926 1.00 31.23 ? 127 ASN B CG 1 ATOM 472 O OD1 . ASN A 1 71 ? 61.738 80.524 -40.515 1.00 40.58 ? 127 ASN B OD1 1 ATOM 473 N ND2 . ASN A 1 71 ? 60.237 78.887 -40.220 1.00 27.60 ? 127 ASN B ND2 1 ATOM 474 N N . SER A 1 72 ? 60.749 81.758 -44.561 1.00 39.71 ? 128 SER B N 1 ATOM 475 C CA . SER A 1 72 ? 60.807 81.918 -46.008 1.00 38.56 ? 128 SER B CA 1 ATOM 476 C C . SER A 1 72 ? 60.738 80.629 -46.840 1.00 39.72 ? 128 SER B C 1 ATOM 477 O O . SER A 1 72 ? 61.047 80.660 -48.023 1.00 39.98 ? 128 SER B O 1 ATOM 478 C CB . SER A 1 72 ? 61.964 82.807 -46.435 1.00 38.33 ? 128 SER B CB 1 ATOM 479 O OG . SER A 1 72 ? 61.544 83.642 -47.495 1.00 40.14 ? 128 SER B OG 1 ATOM 480 N N . LEU A 1 73 ? 60.408 79.502 -46.210 1.00 39.78 ? 129 LEU B N 1 ATOM 481 C CA . LEU A 1 73 ? 60.406 78.187 -46.878 1.00 39.10 ? 129 LEU B CA 1 ATOM 482 C C . LEU A 1 73 ? 59.670 78.140 -48.223 1.00 41.51 ? 129 LEU B C 1 ATOM 483 O O . LEU A 1 73 ? 58.601 78.732 -48.389 1.00 39.54 ? 129 LEU B O 1 ATOM 484 C CB . LEU A 1 73 ? 59.802 77.116 -45.959 1.00 35.31 ? 129 LEU B CB 1 ATOM 485 C CG . LEU A 1 73 ? 60.368 76.992 -44.543 1.00 38.54 ? 129 LEU B CG 1 ATOM 486 C CD1 . LEU A 1 73 ? 59.520 76.049 -43.690 1.00 28.65 ? 129 LEU B CD1 1 ATOM 487 C CD2 . LEU A 1 73 ? 61.828 76.538 -44.583 1.00 44.23 ? 129 LEU B CD2 1 ATOM 488 N N . SER A 1 74 ? 60.262 77.421 -49.175 1.00 42.58 ? 130 SER B N 1 ATOM 489 C CA . SER A 1 74 ? 59.709 77.281 -50.522 1.00 38.59 ? 130 SER B CA 1 ATOM 490 C C . SER A 1 74 ? 59.538 75.805 -50.900 1.00 37.69 ? 130 SER B C 1 ATOM 491 O O . SER A 1 74 ? 59.764 74.915 -50.072 1.00 38.68 ? 130 SER B O 1 ATOM 492 C CB . SER A 1 74 ? 60.597 78.002 -51.549 1.00 35.34 ? 130 SER B CB 1 ATOM 493 O OG . SER A 1 74 ? 61.978 77.734 -51.327 1.00 39.19 ? 130 SER B OG 1 ATOM 494 N N . GLY A 1 75 ? 59.128 75.556 -52.144 1.00 32.18 ? 131 GLY B N 1 ATOM 495 C CA . GLY A 1 75 ? 58.876 74.205 -52.621 1.00 27.07 ? 131 GLY B CA 1 ATOM 496 C C . GLY A 1 75 ? 57.520 73.635 -52.233 1.00 33.85 ? 131 GLY B C 1 ATOM 497 O O . GLY A 1 75 ? 56.657 74.351 -51.735 1.00 42.54 ? 131 GLY B O 1 ATOM 498 N N . ASP A 1 76 ? 57.339 72.338 -52.467 1.00 40.65 ? 132 ASP B N 1 ATOM 499 C CA . ASP A 1 76 ? 56.122 71.613 -52.088 1.00 40.88 ? 132 ASP B CA 1 ATOM 500 C C . ASP A 1 76 ? 55.981 71.334 -50.597 1.00 36.16 ? 132 ASP B C 1 ATOM 501 O O . ASP A 1 76 ? 56.949 71.387 -49.842 1.00 37.37 ? 132 ASP B O 1 ATOM 502 C CB . ASP A 1 76 ? 56.052 70.275 -52.819 1.00 49.31 ? 132 ASP B CB 1 ATOM 503 C CG . ASP A 1 76 ? 55.543 70.417 -54.221 1.00 57.41 ? 132 ASP B CG 1 ATOM 504 O OD1 . ASP A 1 76 ? 55.905 71.419 -54.872 1.00 63.63 ? 132 ASP B OD1 1 ATOM 505 O OD2 . ASP A 1 76 ? 54.773 69.538 -54.665 1.00 59.23 ? 132 ASP B OD2 1 ATOM 506 N N . ILE A 1 77 ? 54.754 71.040 -50.182 1.00 34.09 ? 133 ILE B N 1 ATOM 507 C CA . ILE A 1 77 ? 54.526 70.449 -48.879 1.00 30.46 ? 133 ILE B CA 1 ATOM 508 C C . ILE A 1 77 ? 54.669 68.955 -49.108 1.00 29.68 ? 133 ILE B C 1 ATOM 509 O O . ILE A 1 77 ? 53.770 68.326 -49.675 1.00 27.41 ? 133 ILE B O 1 ATOM 510 C CB . ILE A 1 77 ? 53.093 70.722 -48.386 1.00 25.23 ? 133 ILE B CB 1 ATOM 511 C CG1 . ILE A 1 77 ? 52.874 72.219 -48.170 1.00 22.54 ? 133 ILE B CG1 1 ATOM 512 C CG2 . ILE A 1 77 ? 52.795 69.926 -47.108 1.00 23.67 ? 133 ILE B CG2 1 ATOM 513 C CD1 . ILE A 1 77 ? 51.428 72.582 -47.838 1.00 25.46 ? 133 ILE B CD1 1 ATOM 514 N N . PRO A 1 78 ? 55.791 68.375 -48.654 1.00 26.29 ? 134 PRO B N 1 ATOM 515 C CA . PRO A 1 78 ? 56.091 66.976 -48.960 1.00 27.08 ? 134 PRO B CA 1 ATOM 516 C C . PRO A 1 78 ? 54.969 66.058 -48.488 1.00 34.15 ? 134 PRO B C 1 ATOM 517 O O . PRO A 1 78 ? 54.394 66.259 -47.418 1.00 37.67 ? 134 PRO B O 1 ATOM 518 C CB . PRO A 1 78 ? 57.373 66.709 -48.165 1.00 28.25 ? 134 PRO B CB 1 ATOM 519 C CG . PRO A 1 78 ? 57.974 68.035 -47.963 1.00 28.97 ? 134 PRO B CG 1 ATOM 520 C CD . PRO A 1 78 ? 56.832 68.994 -47.824 1.00 26.92 ? 134 PRO B CD 1 ATOM 521 N N . VAL A 1 79 ? 54.661 65.062 -49.304 1.00 27.93 ? 135 VAL B N 1 ATOM 522 C CA . VAL A 1 79 ? 53.603 64.097 -49.030 1.00 29.70 ? 135 VAL B CA 1 ATOM 523 C C . VAL A 1 79 ? 53.934 63.282 -47.777 1.00 34.01 ? 135 VAL B C 1 ATOM 524 O O . VAL A 1 79 ? 53.043 62.883 -47.020 1.00 26.19 ? 135 VAL B O 1 ATOM 525 C CB . VAL A 1 79 ? 53.409 63.181 -50.276 1.00 41.53 ? 135 VAL B CB 1 ATOM 526 C CG1 . VAL A 1 79 ? 52.603 61.937 -49.959 1.00 26.32 ? 135 VAL B CG1 1 ATOM 527 C CG2 . VAL A 1 79 ? 52.770 63.976 -51.424 1.00 35.38 ? 135 VAL B CG2 1 ATOM 528 N N . GLU A 1 80 ? 55.232 63.078 -47.558 1.00 37.07 ? 136 GLU B N 1 ATOM 529 C CA . GLU A 1 80 ? 55.760 62.353 -46.405 1.00 38.02 ? 136 GLU B CA 1 ATOM 530 C C . GLU A 1 80 ? 55.360 62.976 -45.055 1.00 38.91 ? 136 GLU B C 1 ATOM 531 O O . GLU A 1 80 ? 55.272 62.282 -44.040 1.00 37.72 ? 136 GLU B O 1 ATOM 532 C CB . GLU A 1 80 ? 57.293 62.249 -46.506 1.00 39.41 ? 136 GLU B CB 1 ATOM 533 C CG . GLU A 1 80 ? 57.818 61.316 -47.613 1.00 39.95 ? 136 GLU B CG 1 ATOM 534 C CD . GLU A 1 80 ? 57.632 61.859 -49.041 1.00 40.29 ? 136 GLU B CD 1 ATOM 535 O OE1 . GLU A 1 80 ? 57.246 63.043 -49.207 1.00 29.65 ? 136 GLU B OE1 1 ATOM 536 O OE2 . GLU A 1 80 ? 57.867 61.085 -50.000 1.00 36.38 ? 136 GLU B OE2 1 ATOM 537 N N . ILE A 1 81 ? 55.132 64.285 -45.042 1.00 33.45 ? 137 ILE B N 1 ATOM 538 C CA . ILE A 1 81 ? 54.637 64.960 -43.842 1.00 32.30 ? 137 ILE B CA 1 ATOM 539 C C . ILE A 1 81 ? 53.348 64.310 -43.330 1.00 33.98 ? 137 ILE B C 1 ATOM 540 O O . ILE A 1 81 ? 53.088 64.296 -42.122 1.00 36.91 ? 137 ILE B O 1 ATOM 541 C CB . ILE A 1 81 ? 54.432 66.479 -44.099 1.00 31.42 ? 137 ILE B CB 1 ATOM 542 C CG1 . ILE A 1 81 ? 55.602 67.282 -43.532 1.00 31.86 ? 137 ILE B CG1 1 ATOM 543 C CG2 . ILE A 1 81 ? 53.125 66.982 -43.511 1.00 24.47 ? 137 ILE B CG2 1 ATOM 544 C CD1 . ILE A 1 81 ? 55.513 68.754 -43.849 1.00 25.81 ? 137 ILE B CD1 1 ATOM 545 N N . PHE A 1 82 ? 52.571 63.726 -44.244 1.00 33.56 ? 138 PHE B N 1 ATOM 546 C CA . PHE A 1 82 ? 51.290 63.105 -43.885 1.00 37.78 ? 138 PHE B CA 1 ATOM 547 C C . PHE A 1 82 ? 51.440 61.644 -43.446 1.00 42.69 ? 138 PHE B C 1 ATOM 548 O O . PHE A 1 82 ? 50.451 60.926 -43.260 1.00 39.07 ? 138 PHE B O 1 ATOM 549 C CB . PHE A 1 82 ? 50.261 63.263 -45.004 1.00 40.53 ? 138 PHE B CB 1 ATOM 550 C CG . PHE A 1 82 ? 50.134 64.675 -45.489 1.00 44.62 ? 138 PHE B CG 1 ATOM 551 C CD1 . PHE A 1 82 ? 49.638 65.661 -44.657 1.00 43.89 ? 138 PHE B CD1 1 ATOM 552 C CD2 . PHE A 1 82 ? 50.542 65.025 -46.759 1.00 45.86 ? 138 PHE B CD2 1 ATOM 553 C CE1 . PHE A 1 82 ? 49.539 66.963 -45.087 1.00 40.79 ? 138 PHE B CE1 1 ATOM 554 C CE2 . PHE A 1 82 ? 50.446 66.334 -47.190 1.00 45.15 ? 138 PHE B CE2 1 ATOM 555 C CZ . PHE A 1 82 ? 49.945 67.299 -46.356 1.00 42.46 ? 138 PHE B CZ 1 ATOM 556 N N . ARG A 1 83 ? 52.688 61.206 -43.307 1.00 44.68 ? 139 ARG B N 1 ATOM 557 C CA . ARG A 1 83 ? 52.974 59.938 -42.657 1.00 45.36 ? 139 ARG B CA 1 ATOM 558 C C . ARG A 1 83 ? 52.868 60.059 -41.134 1.00 42.63 ? 139 ARG B C 1 ATOM 559 O O . ARG A 1 83 ? 52.871 59.044 -40.437 1.00 44.16 ? 139 ARG B O 1 ATOM 560 C CB . ARG A 1 83 ? 54.369 59.428 -43.034 1.00 50.78 ? 139 ARG B CB 1 ATOM 561 C CG . ARG A 1 83 ? 54.536 58.998 -44.490 1.00 54.31 ? 139 ARG B CG 1 ATOM 562 C CD . ARG A 1 83 ? 55.987 58.586 -44.746 1.00 63.05 ? 139 ARG B CD 1 ATOM 563 N NE . ARG A 1 83 ? 56.232 58.108 -46.108 1.00 63.73 ? 139 ARG B NE 1 ATOM 564 C CZ . ARG A 1 83 ? 57.448 57.937 -46.617 1.00 58.14 ? 139 ARG B CZ 1 ATOM 565 N NH1 . ARG A 1 83 ? 58.513 58.220 -45.875 1.00 59.59 ? 139 ARG B NH1 1 ATOM 566 N NH2 . ARG A 1 83 ? 57.605 57.494 -47.858 1.00 54.36 ? 139 ARG B NH2 1 ATOM 567 N N . LEU A 1 84 ? 52.730 61.280 -40.610 1.00 39.07 ? 140 LEU B N 1 ATOM 568 C CA . LEU A 1 84 ? 52.797 61.447 -39.163 1.00 36.72 ? 140 LEU B CA 1 ATOM 569 C C . LEU A 1 84 ? 51.396 61.301 -38.610 1.00 35.08 ? 140 LEU B C 1 ATOM 570 O O . LEU A 1 84 ? 50.643 62.265 -38.524 1.00 29.20 ? 140 LEU B O 1 ATOM 571 C CB . LEU A 1 84 ? 53.301 62.857 -38.827 1.00 26.15 ? 140 LEU B CB 1 ATOM 572 C CG . LEU A 1 84 ? 54.581 63.382 -39.476 1.00 27.02 ? 140 LEU B CG 1 ATOM 573 C CD1 . LEU A 1 84 ? 54.772 64.864 -39.246 1.00 32.09 ? 140 LEU B CD1 1 ATOM 574 C CD2 . LEU A 1 84 ? 55.780 62.630 -38.986 1.00 28.34 ? 140 LEU B CD2 1 ATOM 575 N N . LYS A 1 85 ? 51.105 60.124 -38.078 1.00 38.02 ? 141 LYS B N 1 ATOM 576 C CA . LYS A 1 85 ? 49.718 59.737 -37.861 1.00 37.98 ? 141 LYS B CA 1 ATOM 577 C C . LYS A 1 85 ? 49.162 60.358 -36.579 1.00 36.33 ? 141 LYS B C 1 ATOM 578 O O . LYS A 1 85 ? 47.955 60.391 -36.370 1.00 39.23 ? 141 LYS B O 1 ATOM 579 C CB . LYS A 1 85 ? 49.595 58.203 -37.844 1.00 42.50 ? 141 LYS B CB 1 ATOM 580 C CG . LYS A 1 85 ? 48.359 57.638 -38.545 1.00 49.96 ? 141 LYS B CG 1 ATOM 581 C CD . LYS A 1 85 ? 48.446 57.796 -40.054 1.00 61.59 ? 141 LYS B CD 1 ATOM 582 C CE . LYS A 1 85 ? 47.147 57.374 -40.747 1.00 68.55 ? 141 LYS B CE 1 ATOM 583 N NZ . LYS A 1 85 ? 46.862 55.919 -40.649 1.00 73.32 ? 141 LYS B NZ 1 ATOM 584 N N . LYS A 1 86 ? 50.059 60.827 -35.719 1.00 37.38 ? 142 LYS B N 1 ATOM 585 C CA . LYS A 1 86 ? 49.693 61.414 -34.430 1.00 31.37 ? 142 LYS B CA 1 ATOM 586 C C . LYS A 1 86 ? 49.670 62.936 -34.437 1.00 30.99 ? 142 LYS B C 1 ATOM 587 O O . LYS A 1 86 ? 49.557 63.566 -33.387 1.00 39.45 ? 142 LYS B O 1 ATOM 588 C CB . LYS A 1 86 ? 50.613 60.890 -33.320 1.00 34.09 ? 142 LYS B CB 1 ATOM 589 C CG . LYS A 1 86 ? 50.510 59.384 -33.131 1.00 34.83 ? 142 LYS B CG 1 ATOM 590 C CD . LYS A 1 86 ? 51.556 58.837 -32.181 1.00 40.62 ? 142 LYS B CD 1 ATOM 591 C CE . LYS A 1 86 ? 51.363 57.337 -31.997 1.00 46.33 ? 142 LYS B CE 1 ATOM 592 N NZ . LYS A 1 86 ? 51.949 56.829 -30.719 1.00 53.84 ? 142 LYS B NZ 1 ATOM 593 N N . LEU A 1 87 ? 49.851 63.531 -35.605 1.00 28.23 ? 143 LEU B N 1 ATOM 594 C CA . LEU A 1 87 ? 49.912 64.980 -35.692 1.00 24.49 ? 143 LEU B CA 1 ATOM 595 C C . LEU A 1 87 ? 48.564 65.614 -35.355 1.00 23.69 ? 143 LEU B C 1 ATOM 596 O O . LEU A 1 87 ? 47.521 65.148 -35.818 1.00 22.55 ? 143 LEU B O 1 ATOM 597 C CB . LEU A 1 87 ? 50.358 65.401 -37.082 1.00 25.81 ? 143 LEU B CB 1 ATOM 598 C CG . LEU A 1 87 ? 50.879 66.824 -37.155 1.00 25.28 ? 143 LEU B CG 1 ATOM 599 C CD1 . LEU A 1 87 ? 52.181 66.904 -36.387 1.00 23.78 ? 143 LEU B CD1 1 ATOM 600 C CD2 . LEU A 1 87 ? 51.063 67.234 -38.618 1.00 24.77 ? 143 LEU B CD2 1 ATOM 601 N N . LYS A 1 88 ? 48.610 66.673 -34.545 1.00 21.07 ? 144 LYS B N 1 ATOM 602 C CA . LYS A 1 88 ? 47.434 67.406 -34.070 1.00 19.94 ? 144 LYS B CA 1 ATOM 603 C C . LYS A 1 88 ? 47.423 68.856 -34.562 1.00 22.58 ? 144 LYS B C 1 ATOM 604 O O . LYS A 1 88 ? 46.389 69.365 -34.997 1.00 24.86 ? 144 LYS B O 1 ATOM 605 C CB . LYS A 1 88 ? 47.227 67.278 -32.559 1.00 19.88 ? 144 LYS B CB 1 ATOM 606 C CG . LYS A 1 88 ? 46.678 65.917 -32.146 1.00 25.82 ? 144 LYS B CG 1 ATOM 607 C CD . LYS A 1 88 ? 46.748 65.706 -30.639 1.00 33.68 ? 144 LYS B CD 1 ATOM 608 C CE . LYS A 1 88 ? 45.758 66.613 -29.888 1.00 39.87 ? 144 LYS B CE 1 ATOM 609 N NZ . LYS A 1 88 ? 46.035 66.736 -28.413 1.00 38.36 ? 144 LYS B NZ 1 ATOM 610 N N . THR A 1 89 ? 48.525 69.562 -34.357 1.00 20.04 ? 145 THR B N 1 ATOM 611 C CA . THR A 1 89 ? 48.715 70.855 -35.008 1.00 19.75 ? 145 THR B CA 1 ATOM 612 C C . THR A 1 89 ? 49.676 70.746 -36.186 1.00 24.09 ? 145 THR B C 1 ATOM 613 O O . THR A 1 89 ? 50.771 70.190 -36.055 1.00 28.22 ? 145 THR B O 1 ATOM 614 C CB . THR A 1 89 ? 49.309 71.888 -34.039 1.00 24.86 ? 145 THR B CB 1 ATOM 615 O OG1 . THR A 1 89 ? 48.440 72.038 -32.915 1.00 23.57 ? 145 THR B OG1 1 ATOM 616 C CG2 . THR A 1 89 ? 49.469 73.227 -34.724 1.00 24.68 ? 145 THR B CG2 1 ATOM 617 N N . LEU A 1 90 ? 49.262 71.261 -37.341 1.00 22.94 ? 146 LEU B N 1 ATOM 618 C CA . LEU A 1 90 ? 50.183 71.467 -38.454 1.00 27.20 ? 146 LEU B CA 1 ATOM 619 C C . LEU A 1 90 ? 50.164 72.940 -38.827 1.00 20.12 ? 146 LEU B C 1 ATOM 620 O O . LEU A 1 90 ? 49.173 73.426 -39.341 1.00 19.20 ? 146 LEU B O 1 ATOM 621 C CB . LEU A 1 90 ? 49.793 70.614 -39.665 1.00 25.50 ? 146 LEU B CB 1 ATOM 622 C CG . LEU A 1 90 ? 50.678 70.794 -40.919 1.00 25.21 ? 146 LEU B CG 1 ATOM 623 C CD1 . LEU A 1 90 ? 52.126 70.446 -40.621 1.00 22.44 ? 146 LEU B CD1 1 ATOM 624 C CD2 . LEU A 1 90 ? 50.172 69.985 -42.087 1.00 21.07 ? 146 LEU B CD2 1 ATOM 625 N N . SER A 1 91 ? 51.255 73.650 -38.550 1.00 35.25 ? 147 SER B N 1 ATOM 626 C CA . SER A 1 91 ? 51.319 75.080 -38.818 1.00 29.43 ? 147 SER B CA 1 ATOM 627 C C . SER A 1 91 ? 52.395 75.357 -39.867 1.00 30.49 ? 147 SER B C 1 ATOM 628 O O . SER A 1 91 ? 53.582 75.416 -39.555 1.00 40.49 ? 147 SER B O 1 ATOM 629 C CB . SER A 1 91 ? 51.689 75.788 -37.505 1.00 23.12 ? 147 SER B CB 1 ATOM 630 O OG . SER A 1 91 ? 50.950 76.974 -37.284 1.00 25.89 ? 147 SER B OG 1 ATOM 631 N N . LEU A 1 92 ? 51.980 75.527 -41.114 1.00 24.16 ? 148 LEU B N 1 ATOM 632 C CA . LEU A 1 92 ? 52.894 75.891 -42.198 1.00 21.33 ? 148 LEU B CA 1 ATOM 633 C C . LEU A 1 92 ? 52.763 77.314 -42.742 1.00 30.42 ? 148 LEU B C 1 ATOM 634 O O . LEU A 1 92 ? 53.378 77.650 -43.747 1.00 21.20 ? 148 LEU B O 1 ATOM 635 C CB . LEU A 1 92 ? 52.855 74.859 -43.316 1.00 21.61 ? 148 LEU B CB 1 ATOM 636 C CG . LEU A 1 92 ? 53.122 73.434 -42.842 1.00 25.14 ? 148 LEU B CG 1 ATOM 637 C CD1 . LEU A 1 92 ? 52.961 72.467 -44.009 1.00 25.52 ? 148 LEU B CD1 1 ATOM 638 C CD2 . LEU A 1 92 ? 54.503 73.316 -42.208 1.00 23.44 ? 148 LEU B CD2 1 ATOM 639 N N . ASN A 1 93 ? 51.910 78.118 -42.120 1.00 19.91 ? 149 ASN B N 1 ATOM 640 C CA . ASN A 1 93 ? 51.525 79.424 -42.660 1.00 19.25 ? 149 ASN B CA 1 ATOM 641 C C . ASN A 1 93 ? 52.688 80.416 -42.792 1.00 19.91 ? 149 ASN B C 1 ATOM 642 O O . ASN A 1 93 ? 53.739 80.226 -42.198 1.00 20.82 ? 149 ASN B O 1 ATOM 643 C CB . ASN A 1 93 ? 50.403 80.031 -41.811 1.00 18.23 ? 149 ASN B CB 1 ATOM 644 C CG . ASN A 1 93 ? 50.799 80.178 -40.355 1.00 18.53 ? 149 ASN B CG 1 ATOM 645 O OD1 . ASN A 1 93 ? 50.739 79.224 -39.586 1.00 19.73 ? 149 ASN B OD1 1 ATOM 646 N ND2 . ASN A 1 93 ? 51.221 81.373 -39.975 1.00 20.25 ? 149 ASN B ND2 1 ATOM 647 N N . THR A 1 94 ? 52.497 81.444 -43.616 1.00 24.46 ? 150 THR B N 1 ATOM 648 C CA . THR A 1 94 ? 53.481 82.514 -43.819 1.00 19.99 ? 150 THR B CA 1 ATOM 649 C C . THR A 1 94 ? 54.831 82.008 -44.308 1.00 23.27 ? 150 THR B C 1 ATOM 650 O O . THR A 1 94 ? 55.852 82.113 -43.621 1.00 23.18 ? 150 THR B O 1 ATOM 651 C CB . THR A 1 94 ? 53.694 83.346 -42.563 1.00 28.70 ? 150 THR B CB 1 ATOM 652 O OG1 . THR A 1 94 ? 52.475 83.381 -41.813 1.00 29.82 ? 150 THR B OG1 1 ATOM 653 C CG2 . THR A 1 94 ? 54.121 84.768 -42.941 1.00 20.01 ? 150 THR B CG2 1 ATOM 654 N N . ASN A 1 95 ? 54.812 81.456 -45.509 1.00 24.23 ? 151 ASN B N 1 ATOM 655 C CA . ASN A 1 95 ? 56.007 80.999 -46.176 1.00 28.86 ? 151 ASN B CA 1 ATOM 656 C C . ASN A 1 95 ? 55.824 81.246 -47.666 1.00 31.29 ? 151 ASN B C 1 ATOM 657 O O . ASN A 1 95 ? 54.895 81.945 -48.078 1.00 35.01 ? 151 ASN B O 1 ATOM 658 C CB . ASN A 1 95 ? 56.229 79.510 -45.912 1.00 28.16 ? 151 ASN B CB 1 ATOM 659 C CG . ASN A 1 95 ? 56.820 79.241 -44.551 1.00 32.76 ? 151 ASN B CG 1 ATOM 660 O OD1 . ASN A 1 95 ? 57.972 79.573 -44.293 1.00 24.54 ? 151 ASN B OD1 1 ATOM 661 N ND2 . ASN A 1 95 ? 56.043 78.614 -43.677 1.00 34.27 ? 151 ASN B ND2 1 ATOM 662 N N . ASN A 1 96 ? 56.734 80.704 -48.460 1.00 23.11 ? 152 ASN B N 1 ATOM 663 C CA . ASN A 1 96 ? 56.622 80.710 -49.917 1.00 32.08 ? 152 ASN B CA 1 ATOM 664 C C . ASN A 1 96 ? 56.095 79.415 -50.544 1.00 35.86 ? 152 ASN B C 1 ATOM 665 O O . ASN A 1 96 ? 56.271 79.179 -51.743 1.00 42.23 ? 152 ASN B O 1 ATOM 666 C CB . ASN A 1 96 ? 57.901 81.214 -50.564 1.00 34.08 ? 152 ASN B CB 1 ATOM 667 C CG . ASN A 1 96 ? 58.196 82.647 -50.182 1.00 38.98 ? 152 ASN B CG 1 ATOM 668 O OD1 . ASN A 1 96 ? 57.279 83.465 -50.071 1.00 41.12 ? 152 ASN B OD1 1 ATOM 669 N ND2 . ASN A 1 96 ? 59.472 82.956 -49.946 1.00 38.50 ? 152 ASN B ND2 1 ATOM 670 N N . LEU A 1 97 ? 55.552 78.537 -49.704 1.00 23.89 ? 153 LEU B N 1 ATOM 671 C CA . LEU A 1 97 ? 55.179 77.189 -50.125 1.00 23.77 ? 153 LEU B CA 1 ATOM 672 C C . LEU A 1 97 ? 54.286 77.111 -51.366 1.00 23.01 ? 153 LEU B C 1 ATOM 673 O O . LEU A 1 97 ? 53.254 77.771 -51.442 1.00 26.70 ? 153 LEU B O 1 ATOM 674 C CB . LEU A 1 97 ? 54.557 76.441 -48.946 1.00 22.55 ? 153 LEU B CB 1 ATOM 675 C CG . LEU A 1 97 ? 55.603 76.200 -47.860 1.00 23.46 ? 153 LEU B CG 1 ATOM 676 C CD1 . LEU A 1 97 ? 54.975 75.836 -46.533 1.00 23.04 ? 153 LEU B CD1 1 ATOM 677 C CD2 . LEU A 1 97 ? 56.569 75.123 -48.320 1.00 24.62 ? 153 LEU B CD2 1 ATOM 678 N N . GLU A 1 98 ? 54.698 76.299 -52.338 1.00 30.36 ? 154 GLU B N 1 ATOM 679 C CA . GLU A 1 98 ? 53.949 76.151 -53.596 1.00 30.30 ? 154 GLU B CA 1 ATOM 680 C C . GLU A 1 98 ? 53.439 74.724 -53.792 1.00 23.12 ? 154 GLU B C 1 ATOM 681 O O . GLU A 1 98 ? 53.710 73.850 -52.975 1.00 27.37 ? 154 GLU B O 1 ATOM 682 C CB . GLU A 1 98 ? 54.796 76.587 -54.794 1.00 29.84 ? 154 GLU B CB 1 ATOM 683 C CG . GLU A 1 98 ? 56.206 76.010 -54.799 1.00 44.89 ? 154 GLU B CG 1 ATOM 684 C CD . GLU A 1 98 ? 56.979 76.309 -56.085 1.00 59.78 ? 154 GLU B CD 1 ATOM 685 O OE1 . GLU A 1 98 ? 56.360 76.738 -57.090 1.00 58.23 ? 154 GLU B OE1 1 ATOM 686 O OE2 . GLU A 1 98 ? 58.215 76.103 -56.087 1.00 67.77 ? 154 GLU B OE2 1 ATOM 687 N N . GLY A 1 99 ? 52.690 74.491 -54.864 1.00 21.98 ? 155 GLY B N 1 ATOM 688 C CA . GLY A 1 99 ? 52.111 73.178 -55.105 1.00 27.67 ? 155 GLY B CA 1 ATOM 689 C C . GLY A 1 99 ? 50.653 72.974 -54.701 1.00 28.63 ? 155 GLY B C 1 ATOM 690 O O . GLY A 1 99 ? 49.963 73.907 -54.293 1.00 31.47 ? 155 GLY B O 1 ATOM 691 N N . HIS A 1 100 ? 50.171 71.747 -54.870 1.00 25.16 ? 156 HIS B N 1 ATOM 692 C CA . HIS A 1 100 ? 48.863 71.342 -54.372 1.00 20.22 ? 156 HIS B CA 1 ATOM 693 C C . HIS A 1 100 ? 48.909 70.935 -52.897 1.00 33.78 ? 156 HIS B C 1 ATOM 694 O O . HIS A 1 100 ? 49.957 70.564 -52.375 1.00 38.48 ? 156 HIS B O 1 ATOM 695 C CB . HIS A 1 100 ? 48.283 70.200 -55.209 1.00 20.29 ? 156 HIS B CB 1 ATOM 696 C CG . HIS A 1 100 ? 47.940 70.591 -56.614 1.00 46.53 ? 156 HIS B CG 1 ATOM 697 N ND1 . HIS A 1 100 ? 47.109 69.835 -57.415 1.00 47.54 ? 156 HIS B ND1 1 ATOM 698 C CD2 . HIS A 1 100 ? 48.320 71.654 -57.365 1.00 48.27 ? 156 HIS B CD2 1 ATOM 699 C CE1 . HIS A 1 100 ? 46.987 70.418 -58.596 1.00 50.06 ? 156 HIS B CE1 1 ATOM 700 N NE2 . HIS A 1 100 ? 47.713 71.522 -58.593 1.00 49.19 ? 156 HIS B NE2 1 ATOM 701 N N . ILE A 1 101 ? 47.773 71.031 -52.220 1.00 28.68 ? 157 ILE B N 1 ATOM 702 C CA . ILE A 1 101 ? 47.618 70.345 -50.957 1.00 27.93 ? 157 ILE B CA 1 ATOM 703 C C . ILE A 1 101 ? 47.327 68.899 -51.323 1.00 30.37 ? 157 ILE B C 1 ATOM 704 O O . ILE A 1 101 ? 46.286 68.608 -51.909 1.00 28.16 ? 157 ILE B O 1 ATOM 705 C CB . ILE A 1 101 ? 46.441 70.896 -50.139 1.00 27.76 ? 157 ILE B CB 1 ATOM 706 C CG1 . ILE A 1 101 ? 46.573 72.412 -49.939 1.00 26.76 ? 157 ILE B CG1 1 ATOM 707 C CG2 . ILE A 1 101 ? 46.359 70.189 -48.796 1.00 27.07 ? 157 ILE B CG2 1 ATOM 708 C CD1 . ILE A 1 101 ? 45.376 73.040 -49.275 1.00 16.88 ? 157 ILE B CD1 1 ATOM 709 N N . PRO A 1 102 ? 48.251 67.987 -50.982 1.00 29.58 ? 158 PRO B N 1 ATOM 710 C CA . PRO A 1 102 ? 48.188 66.562 -51.337 1.00 24.46 ? 158 PRO B CA 1 ATOM 711 C C . PRO A 1 102 ? 46.912 65.890 -50.797 1.00 30.39 ? 158 PRO B C 1 ATOM 712 O O . PRO A 1 102 ? 46.455 66.306 -49.739 1.00 31.59 ? 158 PRO B O 1 ATOM 713 C CB . PRO A 1 102 ? 49.419 65.985 -50.628 1.00 30.71 ? 158 PRO B CB 1 ATOM 714 C CG . PRO A 1 102 ? 50.323 67.174 -50.389 1.00 29.01 ? 158 PRO B CG 1 ATOM 715 C CD . PRO A 1 102 ? 49.394 68.287 -50.102 1.00 27.41 ? 158 PRO B CD 1 ATOM 716 N N . MET A 1 103 ? 46.362 64.885 -51.488 1.00 27.50 ? 159 MET B N 1 ATOM 717 C CA . MET A 1 103 ? 45.191 64.154 -50.986 1.00 25.43 ? 159 MET B CA 1 ATOM 718 C C . MET A 1 103 ? 45.499 63.419 -49.685 1.00 32.33 ? 159 MET B C 1 ATOM 719 O O . MET A 1 103 ? 44.633 63.269 -48.808 1.00 34.59 ? 159 MET B O 1 ATOM 720 C CB . MET A 1 103 ? 44.694 63.129 -52.002 1.00 33.31 ? 159 MET B CB 1 ATOM 721 C CG . MET A 1 103 ? 44.277 63.707 -53.353 1.00 44.06 ? 159 MET B CG 1 ATOM 722 S SD . MET A 1 103 ? 42.791 64.749 -53.328 1.00 214.61 ? 159 MET B SD 1 ATOM 723 C CE . MET A 1 103 ? 41.506 63.600 -52.832 1.00 52.46 ? 159 MET B CE 1 ATOM 724 N N . GLU A 1 104 ? 46.750 62.996 -49.533 1.00 35.25 ? 160 GLU B N 1 ATOM 725 C CA . GLU A 1 104 ? 47.128 62.167 -48.395 1.00 32.61 ? 160 GLU B CA 1 ATOM 726 C C . GLU A 1 104 ? 46.915 62.910 -47.093 1.00 32.50 ? 160 GLU B C 1 ATOM 727 O O . GLU A 1 104 ? 47.105 62.347 -46.029 1.00 36.84 ? 160 GLU B O 1 ATOM 728 C CB . GLU A 1 104 ? 48.586 61.710 -48.483 1.00 35.96 ? 160 GLU B CB 1 ATOM 729 C CG . GLU A 1 104 ? 48.869 60.706 -49.573 1.00 43.71 ? 160 GLU B CG 1 ATOM 730 C CD . GLU A 1 104 ? 49.159 61.359 -50.914 1.00 49.01 ? 160 GLU B CD 1 ATOM 731 O OE1 . GLU A 1 104 ? 49.059 62.602 -51.021 1.00 48.50 ? 160 GLU B OE1 1 ATOM 732 O OE2 . GLU A 1 104 ? 49.494 60.621 -51.863 1.00 51.91 ? 160 GLU B OE2 1 ATOM 733 N N . ILE A 1 105 ? 46.554 64.186 -47.177 1.00 34.20 ? 161 ILE B N 1 ATOM 734 C CA . ILE A 1 105 ? 46.273 64.963 -45.979 1.00 31.25 ? 161 ILE B CA 1 ATOM 735 C C . ILE A 1 105 ? 45.138 64.332 -45.192 1.00 27.77 ? 161 ILE B C 1 ATOM 736 O O . ILE A 1 105 ? 45.109 64.415 -43.964 1.00 29.27 ? 161 ILE B O 1 ATOM 737 C CB . ILE A 1 105 ? 45.951 66.445 -46.278 1.00 30.84 ? 161 ILE B CB 1 ATOM 738 C CG1 . ILE A 1 105 ? 46.056 67.262 -44.989 1.00 19.11 ? 161 ILE B CG1 1 ATOM 739 C CG2 . ILE A 1 105 ? 44.570 66.597 -46.936 1.00 25.47 ? 161 ILE B CG2 1 ATOM 740 C CD1 . ILE A 1 105 ? 45.720 68.701 -45.155 1.00 21.94 ? 161 ILE B CD1 1 ATOM 741 N N . GLY A 1 106 ? 44.230 63.656 -45.886 1.00 26.94 ? 162 GLY B N 1 ATOM 742 C CA . GLY A 1 106 ? 43.140 62.982 -45.199 1.00 28.18 ? 162 GLY B CA 1 ATOM 743 C C . GLY A 1 106 ? 43.620 61.848 -44.300 1.00 29.00 ? 162 GLY B C 1 ATOM 744 O O . GLY A 1 106 ? 42.841 61.252 -43.556 1.00 27.30 ? 162 GLY B O 1 ATOM 745 N N . ASN A 1 107 ? 44.908 61.539 -44.368 1.00 31.90 ? 163 ASN B N 1 ATOM 746 C CA . ASN A 1 107 ? 45.464 60.482 -43.538 1.00 37.51 ? 163 ASN B CA 1 ATOM 747 C C . ASN A 1 107 ? 45.747 60.915 -42.108 1.00 41.90 ? 163 ASN B C 1 ATOM 748 O O . ASN A 1 107 ? 45.837 60.068 -41.226 1.00 47.66 ? 163 ASN B O 1 ATOM 749 C CB . ASN A 1 107 ? 46.724 59.887 -44.162 1.00 40.27 ? 163 ASN B CB 1 ATOM 750 C CG . ASN A 1 107 ? 46.520 58.463 -44.646 1.00 49.59 ? 163 ASN B CG 1 ATOM 751 O OD1 . ASN A 1 107 ? 46.881 57.501 -43.957 1.00 55.11 ? 163 ASN B OD1 1 ATOM 752 N ND2 . ASN A 1 107 ? 45.948 58.317 -45.841 1.00 46.74 ? 163 ASN B ND2 1 ATOM 753 N N . LEU A 1 108 ? 45.837 62.217 -41.842 1.00 38.50 ? 164 LEU B N 1 ATOM 754 C CA . LEU A 1 108 ? 46.254 62.596 -40.505 1.00 33.48 ? 164 LEU B CA 1 ATOM 755 C C . LEU A 1 108 ? 44.985 62.612 -39.708 1.00 37.33 ? 164 LEU B C 1 ATOM 756 O O . LEU A 1 108 ? 44.318 63.632 -39.592 1.00 36.78 ? 164 LEU B O 1 ATOM 757 C CB . LEU A 1 108 ? 46.803 64.016 -40.510 1.00 20.69 ? 164 LEU B CB 1 ATOM 758 C CG . LEU A 1 108 ? 48.045 64.309 -41.349 1.00 21.50 ? 164 LEU B CG 1 ATOM 759 C CD1 . LEU A 1 108 ? 48.427 65.769 -41.211 1.00 21.23 ? 164 LEU B CD1 1 ATOM 760 C CD2 . LEU A 1 108 ? 49.184 63.424 -40.928 1.00 22.68 ? 164 LEU B CD2 1 ATOM 761 N N . SER A 1 109 ? 44.769 61.513 -39.006 1.00 40.01 ? 165 SER B N 1 ATOM 762 C CA . SER A 1 109 ? 43.453 61.154 -38.529 1.00 34.63 ? 165 SER B CA 1 ATOM 763 C C . SER A 1 109 ? 43.045 62.069 -37.388 1.00 35.99 ? 165 SER B C 1 ATOM 764 O O . SER A 1 109 ? 41.864 62.343 -37.199 1.00 37.59 ? 165 SER B O 1 ATOM 765 C CB . SER A 1 109 ? 43.464 59.688 -38.080 1.00 36.12 ? 165 SER B CB 1 ATOM 766 O OG . SER A 1 109 ? 42.159 59.149 -38.001 1.00 35.13 ? 165 SER B OG 1 ATOM 767 N N . GLY A 1 110 ? 44.031 62.536 -36.629 1.00 40.04 ? 166 GLY B N 1 ATOM 768 C CA . GLY A 1 110 ? 43.775 63.342 -35.452 1.00 18.74 ? 166 GLY B CA 1 ATOM 769 C C . GLY A 1 110 ? 44.151 64.806 -35.543 1.00 18.47 ? 166 GLY B C 1 ATOM 770 O O . GLY A 1 110 ? 44.267 65.477 -34.523 1.00 31.52 ? 166 GLY B O 1 ATOM 771 N N . LEU A 1 111 ? 44.377 65.300 -36.753 1.00 18.45 ? 167 LEU B N 1 ATOM 772 C CA . LEU A 1 111 ? 44.598 66.728 -36.958 1.00 19.29 ? 167 LEU B CA 1 ATOM 773 C C . LEU A 1 111 ? 43.470 67.594 -36.377 1.00 25.06 ? 167 LEU B C 1 ATOM 774 O O . LEU A 1 111 ? 42.283 67.341 -36.606 1.00 25.27 ? 167 LEU B O 1 ATOM 775 C CB . LEU A 1 111 ? 44.740 67.045 -38.442 1.00 18.09 ? 167 LEU B CB 1 ATOM 776 C CG . LEU A 1 111 ? 45.498 68.340 -38.722 1.00 24.17 ? 167 LEU B CG 1 ATOM 777 C CD1 . LEU A 1 111 ? 46.850 68.263 -38.022 1.00 19.16 ? 167 LEU B CD1 1 ATOM 778 C CD2 . LEU A 1 111 ? 45.658 68.554 -40.217 1.00 18.23 ? 167 LEU B CD2 1 ATOM 779 N N . VAL A 1 112 ? 43.869 68.615 -35.624 1.00 17.89 ? 168 VAL B N 1 ATOM 780 C CA . VAL A 1 112 ? 42.954 69.585 -35.050 1.00 17.48 ? 168 VAL B CA 1 ATOM 781 C C . VAL A 1 112 ? 43.179 70.958 -35.686 1.00 22.22 ? 168 VAL B C 1 ATOM 782 O O . VAL A 1 112 ? 42.240 71.581 -36.189 1.00 22.48 ? 168 VAL B O 1 ATOM 783 C CB . VAL A 1 112 ? 42.999 69.614 -33.502 1.00 21.49 ? 168 VAL B CB 1 ATOM 784 C CG1 . VAL A 1 112 ? 42.066 70.711 -32.957 1.00 15.08 ? 168 VAL B CG1 1 ATOM 785 C CG2 . VAL A 1 112 ? 42.605 68.246 -32.947 1.00 16.24 ? 168 VAL B CG2 1 ATOM 786 N N . GLU A 1 113 ? 44.411 71.450 -35.602 1.00 22.50 ? 169 GLU B N 1 ATOM 787 C CA . GLU A 1 113 ? 44.766 72.732 -36.208 1.00 22.08 ? 169 GLU B CA 1 ATOM 788 C C . GLU A 1 113 ? 45.494 72.574 -37.538 1.00 27.46 ? 169 GLU B C 1 ATOM 789 O O . GLU A 1 113 ? 46.486 71.854 -37.632 1.00 30.06 ? 169 GLU B O 1 ATOM 790 C CB . GLU A 1 113 ? 45.638 73.530 -35.243 1.00 16.64 ? 169 GLU B CB 1 ATOM 791 C CG . GLU A 1 113 ? 45.128 73.503 -33.800 1.00 29.66 ? 169 GLU B CG 1 ATOM 792 C CD . GLU A 1 113 ? 43.789 74.190 -33.640 1.00 28.44 ? 169 GLU B CD 1 ATOM 793 O OE1 . GLU A 1 113 ? 43.399 74.958 -34.550 1.00 36.82 ? 169 GLU B OE1 1 ATOM 794 O OE2 . GLU A 1 113 ? 43.121 73.966 -32.610 1.00 21.93 ? 169 GLU B OE2 1 ATOM 795 N N . LEU A 1 114 ? 44.994 73.240 -38.572 1.00 16.23 ? 170 LEU B N 1 ATOM 796 C CA . LEU A 1 114 ? 45.673 73.238 -39.861 1.00 16.71 ? 170 LEU B CA 1 ATOM 797 C C . LEU A 1 114 ? 45.823 74.653 -40.396 1.00 16.38 ? 170 LEU B C 1 ATOM 798 O O . LEU A 1 114 ? 44.842 75.247 -40.859 1.00 16.76 ? 170 LEU B O 1 ATOM 799 C CB . LEU A 1 114 ? 44.871 72.398 -40.857 1.00 16.43 ? 170 LEU B CB 1 ATOM 800 C CG . LEU A 1 114 ? 45.339 72.352 -42.311 1.00 21.04 ? 170 LEU B CG 1 ATOM 801 C CD1 . LEU A 1 114 ? 46.725 71.722 -42.432 1.00 17.96 ? 170 LEU B CD1 1 ATOM 802 C CD2 . LEU A 1 114 ? 44.318 71.602 -43.158 1.00 16.79 ? 170 LEU B CD2 1 ATOM 803 N N . MET A 1 115 ? 47.056 75.165 -40.397 1.00 17.11 ? 171 MET B N 1 ATOM 804 C CA . MET A 1 115 ? 47.315 76.527 -40.854 1.00 20.18 ? 171 MET B CA 1 ATOM 805 C C . MET A 1 115 ? 48.173 76.559 -42.112 1.00 17.51 ? 171 MET B C 1 ATOM 806 O O . MET A 1 115 ? 49.386 76.368 -42.053 1.00 21.29 ? 171 MET B O 1 ATOM 807 C CB . MET A 1 115 ? 48.053 77.284 -39.748 1.00 23.77 ? 171 MET B CB 1 ATOM 808 C CG . MET A 1 115 ? 47.380 77.202 -38.385 1.00 17.63 ? 171 MET B CG 1 ATOM 809 S SD . MET A 1 115 ? 45.833 78.104 -38.386 1.00 32.01 ? 171 MET B SD 1 ATOM 810 C CE . MET A 1 115 ? 45.495 78.215 -36.606 1.00 15.20 ? 171 MET B CE 1 ATOM 811 N N . LEU A 1 116 ? 47.541 76.804 -43.252 1.00 18.24 ? 172 LEU B N 1 ATOM 812 C CA . LEU A 1 116 ? 48.272 76.963 -44.509 1.00 17.48 ? 172 LEU B CA 1 ATOM 813 C C . LEU A 1 116 ? 48.362 78.385 -45.029 1.00 17.15 ? 172 LEU B C 1 ATOM 814 O O . LEU A 1 116 ? 48.917 78.607 -46.089 1.00 17.51 ? 172 LEU B O 1 ATOM 815 C CB . LEU A 1 116 ? 47.726 76.027 -45.581 1.00 17.39 ? 172 LEU B CB 1 ATOM 816 C CG . LEU A 1 116 ? 47.773 74.578 -45.100 1.00 19.00 ? 172 LEU B CG 1 ATOM 817 C CD1 . LEU A 1 116 ? 47.213 73.619 -46.143 1.00 17.79 ? 172 LEU B CD1 1 ATOM 818 C CD2 . LEU A 1 116 ? 49.189 74.189 -44.666 1.00 19.00 ? 172 LEU B CD2 1 ATOM 819 N N . PHE A 1 117 ? 47.800 79.342 -44.295 1.00 35.07 ? 173 PHE B N 1 ATOM 820 C CA . PHE A 1 117 ? 47.564 80.664 -44.864 1.00 15.95 ? 173 PHE B CA 1 ATOM 821 C C . PHE A 1 117 ? 48.819 81.464 -45.243 1.00 16.65 ? 173 PHE B C 1 ATOM 822 O O . PHE A 1 117 ? 49.907 81.221 -44.733 1.00 17.52 ? 173 PHE B O 1 ATOM 823 C CB . PHE A 1 117 ? 46.586 81.485 -44.012 1.00 15.04 ? 173 PHE B CB 1 ATOM 824 C CG . PHE A 1 117 ? 47.035 81.717 -42.597 1.00 24.95 ? 173 PHE B CG 1 ATOM 825 C CD1 . PHE A 1 117 ? 47.863 82.778 -42.284 1.00 23.43 ? 173 PHE B CD1 1 ATOM 826 C CD2 . PHE A 1 117 ? 46.588 80.902 -41.570 1.00 20.37 ? 173 PHE B CD2 1 ATOM 827 C CE1 . PHE A 1 117 ? 48.258 83.006 -40.975 1.00 20.92 ? 173 PHE B CE1 1 ATOM 828 C CE2 . PHE A 1 117 ? 46.979 81.122 -40.263 1.00 21.57 ? 173 PHE B CE2 1 ATOM 829 C CZ . PHE A 1 117 ? 47.815 82.175 -39.964 1.00 22.59 ? 173 PHE B CZ 1 ATOM 830 N N . ASP A 1 118 ? 48.648 82.399 -46.173 1.00 23.54 ? 174 ASP B N 1 ATOM 831 C CA . ASP A 1 118 ? 49.742 83.236 -46.672 1.00 16.89 ? 174 ASP B CA 1 ATOM 832 C C . ASP A 1 118 ? 50.910 82.420 -47.237 1.00 29.03 ? 174 ASP B C 1 ATOM 833 O O . ASP A 1 118 ? 52.022 82.395 -46.697 1.00 18.83 ? 174 ASP B O 1 ATOM 834 C CB . ASP A 1 118 ? 50.212 84.247 -45.616 1.00 20.04 ? 174 ASP B CB 1 ATOM 835 C CG . ASP A 1 118 ? 49.113 85.244 -45.210 1.00 20.67 ? 174 ASP B CG 1 ATOM 836 O OD1 . ASP A 1 118 ? 48.386 85.756 -46.087 1.00 27.56 ? 174 ASP B OD1 1 ATOM 837 O OD2 . ASP A 1 118 ? 48.971 85.520 -44.003 1.00 25.15 ? 174 ASP B OD2 1 ATOM 838 N N . ASN A 1 119 ? 50.638 81.761 -48.352 1.00 26.85 ? 175 ASN B N 1 ATOM 839 C CA . ASN A 1 119 ? 51.647 81.011 -49.064 1.00 18.93 ? 175 ASN B CA 1 ATOM 840 C C . ASN A 1 119 ? 51.470 81.234 -50.565 1.00 20.82 ? 175 ASN B C 1 ATOM 841 O O . ASN A 1 119 ? 50.819 82.185 -50.996 1.00 18.05 ? 175 ASN B O 1 ATOM 842 C CB . ASN A 1 119 ? 51.577 79.525 -48.708 1.00 26.82 ? 175 ASN B CB 1 ATOM 843 C CG . ASN A 1 119 ? 52.355 79.187 -47.453 1.00 30.64 ? 175 ASN B CG 1 ATOM 844 O OD1 . ASN A 1 119 ? 53.532 79.474 -47.365 1.00 36.89 ? 175 ASN B OD1 1 ATOM 845 N ND2 . ASN A 1 119 ? 51.696 78.578 -46.474 1.00 34.08 ? 175 ASN B ND2 1 ATOM 846 N N . LYS A 1 120 ? 52.160 80.424 -51.349 1.00 25.02 ? 176 LYS B N 1 ATOM 847 C CA . LYS A 1 120 ? 52.008 80.378 -52.801 1.00 20.27 ? 176 LYS B CA 1 ATOM 848 C C . LYS A 1 120 ? 51.166 79.212 -53.335 1.00 20.62 ? 176 LYS B C 1 ATOM 849 O O . LYS A 1 120 ? 51.302 78.831 -54.498 1.00 22.07 ? 176 LYS B O 1 ATOM 850 C CB . LYS A 1 120 ? 53.345 80.570 -53.518 1.00 20.51 ? 176 LYS B CB 1 ATOM 851 C CG . LYS A 1 120 ? 53.931 81.958 -53.256 1.00 31.52 ? 176 LYS B CG 1 ATOM 852 C CD . LYS A 1 120 ? 55.162 82.248 -54.114 1.00 43.25 ? 176 LYS B CD 1 ATOM 853 C CE . LYS A 1 120 ? 55.601 83.707 -53.970 1.00 47.35 ? 176 LYS B CE 1 ATOM 854 N NZ . LYS A 1 120 ? 56.805 84.017 -54.794 1.00 47.72 ? 176 LYS B NZ 1 ATOM 855 N N . LEU A 1 121 ? 50.382 78.574 -52.468 1.00 22.30 ? 177 LEU B N 1 ATOM 856 C CA . LEU A 1 121 ? 49.682 77.338 -52.843 1.00 18.70 ? 177 LEU B CA 1 ATOM 857 C C . LEU A 1 121 ? 48.723 77.460 -54.050 1.00 25.32 ? 177 LEU B C 1 ATOM 858 O O . LEU A 1 121 ? 48.268 78.553 -54.397 1.00 31.11 ? 177 LEU B O 1 ATOM 859 C CB . LEU A 1 121 ? 48.913 76.789 -51.638 1.00 18.25 ? 177 LEU B CB 1 ATOM 860 C CG . LEU A 1 121 ? 49.735 76.222 -50.490 1.00 18.96 ? 177 LEU B CG 1 ATOM 861 C CD1 . LEU A 1 121 ? 48.822 75.827 -49.333 1.00 18.37 ? 177 LEU B CD1 1 ATOM 862 C CD2 . LEU A 1 121 ? 50.552 75.034 -50.989 1.00 19.96 ? 177 LEU B CD2 1 ATOM 863 N N . SER A 1 122 ? 48.448 76.322 -54.689 1.00 18.27 ? 178 SER B N 1 ATOM 864 C CA . SER A 1 122 ? 47.573 76.244 -55.862 1.00 27.57 ? 178 SER B CA 1 ATOM 865 C C . SER A 1 122 ? 46.757 74.947 -55.896 1.00 30.12 ? 178 SER B C 1 ATOM 866 O O . SER A 1 122 ? 46.676 74.224 -54.897 1.00 34.69 ? 178 SER B O 1 ATOM 867 C CB . SER A 1 122 ? 48.367 76.413 -57.167 1.00 18.39 ? 178 SER B CB 1 ATOM 868 O OG . SER A 1 122 ? 49.489 75.553 -57.213 1.00 37.68 ? 178 SER B OG 1 ATOM 869 N N . GLY A 1 123 ? 46.133 74.677 -57.041 1.00 17.45 ? 179 GLY B N 1 ATOM 870 C CA . GLY A 1 123 ? 45.271 73.517 -57.200 1.00 23.88 ? 179 GLY B CA 1 ATOM 871 C C . GLY A 1 123 ? 43.958 73.607 -56.433 1.00 27.52 ? 179 GLY B C 1 ATOM 872 O O . GLY A 1 123 ? 43.514 74.687 -56.051 1.00 30.95 ? 179 GLY B O 1 ATOM 873 N N . GLU A 1 124 ? 43.324 72.465 -56.201 1.00 24.80 ? 180 GLU B N 1 ATOM 874 C CA . GLU A 1 124 ? 42.076 72.464 -55.465 1.00 16.54 ? 180 GLU B CA 1 ATOM 875 C C . GLU A 1 124 ? 42.265 72.003 -54.026 1.00 19.96 ? 180 GLU B C 1 ATOM 876 O O . GLU A 1 124 ? 43.334 71.533 -53.626 1.00 28.88 ? 180 GLU B O 1 ATOM 877 C CB . GLU A 1 124 ? 41.057 71.542 -56.141 1.00 21.08 ? 180 GLU B CB 1 ATOM 878 C CG . GLU A 1 124 ? 40.586 71.973 -57.515 1.00 32.81 ? 180 GLU B CG 1 ATOM 879 C CD . GLU A 1 124 ? 39.420 71.127 -58.009 1.00 46.85 ? 180 GLU B CD 1 ATOM 880 O OE1 . GLU A 1 124 ? 39.664 70.104 -58.691 1.00 50.06 ? 180 GLU B OE1 1 ATOM 881 O OE2 . GLU A 1 124 ? 38.255 71.480 -57.707 1.00 52.97 ? 180 GLU B OE2 1 ATOM 882 N N . ILE A 1 125 ? 41.200 72.111 -53.255 1.00 20.21 ? 181 ILE B N 1 ATOM 883 C CA . ILE A 1 125 ? 41.194 71.561 -51.926 1.00 22.88 ? 181 ILE B CA 1 ATOM 884 C C . ILE A 1 125 ? 40.743 70.121 -52.079 1.00 29.71 ? 181 ILE B C 1 ATOM 885 O O . ILE A 1 125 ? 39.712 69.842 -52.695 1.00 33.75 ? 181 ILE B O 1 ATOM 886 C CB . ILE A 1 125 ? 40.249 72.336 -51.028 1.00 21.19 ? 181 ILE B CB 1 ATOM 887 C CG1 . ILE A 1 125 ? 40.834 73.717 -50.758 1.00 18.47 ? 181 ILE B CG1 1 ATOM 888 C CG2 . ILE A 1 125 ? 40.032 71.606 -49.736 1.00 19.12 ? 181 ILE B CG2 1 ATOM 889 C CD1 . ILE A 1 125 ? 39.931 74.607 -49.993 1.00 15.49 ? 181 ILE B CD1 1 ATOM 890 N N . PRO A 1 126 ? 41.540 69.196 -51.548 1.00 25.53 ? 182 PRO B N 1 ATOM 891 C CA . PRO A 1 126 ? 41.305 67.760 -51.703 1.00 20.80 ? 182 PRO B CA 1 ATOM 892 C C . PRO A 1 126 ? 39.949 67.367 -51.140 1.00 21.83 ? 182 PRO B C 1 ATOM 893 O O . PRO A 1 126 ? 39.575 67.910 -50.114 1.00 27.82 ? 182 PRO B O 1 ATOM 894 C CB . PRO A 1 126 ? 42.413 67.144 -50.849 1.00 27.49 ? 182 PRO B CB 1 ATOM 895 C CG . PRO A 1 126 ? 43.463 68.202 -50.769 1.00 26.73 ? 182 PRO B CG 1 ATOM 896 C CD . PRO A 1 126 ? 42.728 69.485 -50.731 1.00 18.50 ? 182 PRO B CD 1 ATOM 897 N N . ARG A 1 127 ? 39.235 66.450 -51.791 1.00 20.20 ? 183 ARG B N 1 ATOM 898 C CA . ARG A 1 127 ? 38.003 65.880 -51.244 1.00 23.84 ? 183 ARG B CA 1 ATOM 899 C C . ARG A 1 127 ? 38.312 65.127 -49.938 1.00 27.61 ? 183 ARG B C 1 ATOM 900 O O . ARG A 1 127 ? 37.417 64.807 -49.153 1.00 34.04 ? 183 ARG B O 1 ATOM 901 C CB . ARG A 1 127 ? 37.336 64.926 -52.255 1.00 36.16 ? 183 ARG B CB 1 ATOM 902 C CG . ARG A 1 127 ? 36.932 65.525 -53.622 1.00 47.40 ? 183 ARG B CG 1 ATOM 903 C CD . ARG A 1 127 ? 35.878 66.632 -53.446 1.00 68.90 ? 183 ARG B CD 1 ATOM 904 N NE . ARG A 1 127 ? 34.915 66.741 -54.541 1.00 83.74 ? 183 ARG B NE 1 ATOM 905 C CZ . ARG A 1 127 ? 33.732 67.342 -54.426 1.00 87.39 ? 183 ARG B CZ 1 ATOM 906 N NH1 . ARG A 1 127 ? 33.370 67.865 -53.270 1.00 88.29 ? 183 ARG B NH1 1 ATOM 907 N NH2 . ARG A 1 127 ? 32.904 67.411 -55.457 1.00 91.90 ? 183 ARG B NH2 1 ATOM 908 N N . SER A 1 128 ? 39.591 64.852 -49.715 1.00 24.21 ? 184 SER B N 1 ATOM 909 C CA . SER A 1 128 ? 40.060 64.154 -48.526 1.00 20.32 ? 184 SER B CA 1 ATOM 910 C C . SER A 1 128 ? 39.810 64.863 -47.193 1.00 24.60 ? 184 SER B C 1 ATOM 911 O O . SER A 1 128 ? 39.808 64.196 -46.156 1.00 21.00 ? 184 SER B O 1 ATOM 912 C CB . SER A 1 128 ? 41.557 63.891 -48.637 1.00 20.32 ? 184 SER B CB 1 ATOM 913 O OG . SER A 1 128 ? 41.797 62.624 -49.195 1.00 35.71 ? 184 SER B OG 1 ATOM 914 N N . ILE A 1 129 ? 39.638 66.191 -47.198 1.00 18.85 ? 185 ILE B N 1 ATOM 915 C CA . ILE A 1 129 ? 39.513 66.913 -45.929 1.00 20.84 ? 185 ILE B CA 1 ATOM 916 C C . ILE A 1 129 ? 38.349 66.377 -45.125 1.00 21.05 ? 185 ILE B C 1 ATOM 917 O O . ILE A 1 129 ? 38.366 66.452 -43.902 1.00 20.44 ? 185 ILE B O 1 ATOM 918 C CB . ILE A 1 129 ? 39.358 68.457 -46.062 1.00 28.87 ? 185 ILE B CB 1 ATOM 919 C CG1 . ILE A 1 129 ? 38.745 68.840 -47.403 1.00 30.49 ? 185 ILE B CG1 1 ATOM 920 C CG2 . ILE A 1 129 ? 40.692 69.174 -45.850 1.00 21.70 ? 185 ILE B CG2 1 ATOM 921 C CD1 . ILE A 1 129 ? 37.292 68.538 -47.527 1.00 30.62 ? 185 ILE B CD1 1 ATOM 922 N N . GLY A 1 130 ? 37.364 65.802 -45.814 1.00 14.33 ? 186 GLY B N 1 ATOM 923 C CA . GLY A 1 130 ? 36.207 65.221 -45.156 1.00 13.88 ? 186 GLY B CA 1 ATOM 924 C C . GLY A 1 130 ? 36.556 64.127 -44.160 1.00 20.96 ? 186 GLY B C 1 ATOM 925 O O . GLY A 1 130 ? 35.793 63.839 -43.251 1.00 26.96 ? 186 GLY B O 1 ATOM 926 N N . GLU A 1 131 ? 37.719 63.516 -44.319 1.00 15.27 ? 187 GLU B N 1 ATOM 927 C CA . GLU A 1 131 ? 38.109 62.429 -43.443 1.00 23.87 ? 187 GLU B CA 1 ATOM 928 C C . GLU A 1 131 ? 38.578 62.935 -42.100 1.00 29.29 ? 187 GLU B C 1 ATOM 929 O O . GLU A 1 131 ? 38.574 62.186 -41.127 1.00 43.58 ? 187 GLU B O 1 ATOM 930 C CB . GLU A 1 131 ? 39.193 61.571 -44.084 1.00 26.99 ? 187 GLU B CB 1 ATOM 931 C CG . GLU A 1 131 ? 38.679 60.689 -45.212 1.00 44.30 ? 187 GLU B CG 1 ATOM 932 C CD . GLU A 1 131 ? 39.804 60.074 -46.021 1.00 64.35 ? 187 GLU B CD 1 ATOM 933 O OE1 . GLU A 1 131 ? 40.982 60.361 -45.706 1.00 68.67 ? 187 GLU B OE1 1 ATOM 934 O OE2 . GLU A 1 131 ? 39.515 59.309 -46.972 1.00 70.86 ? 187 GLU B OE2 1 ATOM 935 N N . LEU A 1 132 ? 38.934 64.213 -42.012 1.00 21.27 ? 188 LEU B N 1 ATOM 936 C CA . LEU A 1 132 ? 39.527 64.678 -40.776 1.00 20.01 ? 188 LEU B CA 1 ATOM 937 C C . LEU A 1 132 ? 38.400 65.113 -39.874 1.00 15.51 ? 188 LEU B C 1 ATOM 938 O O . LEU A 1 132 ? 37.889 66.217 -39.995 1.00 25.59 ? 188 LEU B O 1 ATOM 939 C CB . LEU A 1 132 ? 40.408 65.888 -41.075 1.00 26.46 ? 188 LEU B CB 1 ATOM 940 C CG . LEU A 1 132 ? 41.402 65.713 -42.219 1.00 29.94 ? 188 LEU B CG 1 ATOM 941 C CD1 . LEU A 1 132 ? 41.974 67.046 -42.667 1.00 16.39 ? 188 LEU B CD1 1 ATOM 942 C CD2 . LEU A 1 132 ? 42.504 64.769 -41.782 1.00 17.52 ? 188 LEU B CD2 1 ATOM 943 N N . LYS A 1 133 ? 38.074 64.270 -38.906 1.00 17.52 ? 189 LYS B N 1 ATOM 944 C CA . LYS A 1 133 ? 36.865 64.481 -38.118 1.00 16.49 ? 189 LYS B CA 1 ATOM 945 C C . LYS A 1 133 ? 37.109 65.150 -36.788 1.00 15.18 ? 189 LYS B C 1 ATOM 946 O O . LYS A 1 133 ? 36.168 65.466 -36.068 1.00 26.13 ? 189 LYS B O 1 ATOM 947 C CB . LYS A 1 133 ? 36.091 63.175 -37.939 1.00 25.90 ? 189 LYS B CB 1 ATOM 948 C CG . LYS A 1 133 ? 35.453 62.667 -39.237 1.00 29.25 ? 189 LYS B CG 1 ATOM 949 C CD . LYS A 1 133 ? 34.211 61.831 -38.957 1.00 33.16 ? 189 LYS B CD 1 ATOM 950 C CE . LYS A 1 133 ? 33.297 61.826 -40.165 1.00 36.58 ? 189 LYS B CE 1 ATOM 951 N NZ . LYS A 1 133 ? 34.110 61.775 -41.417 1.00 37.95 ? 189 LYS B NZ 1 ATOM 952 N N . ASN A 1 134 ? 38.374 65.365 -36.455 1.00 20.05 ? 190 ASN B N 1 ATOM 953 C CA . ASN A 1 134 ? 38.729 66.181 -35.303 1.00 14.48 ? 190 ASN B CA 1 ATOM 954 C C . ASN A 1 134 ? 39.124 67.590 -35.694 1.00 14.23 ? 190 ASN B C 1 ATOM 955 O O . ASN A 1 134 ? 39.460 68.404 -34.835 1.00 46.70 ? 190 ASN B O 1 ATOM 956 C CB . ASN A 1 134 ? 39.860 65.526 -34.510 1.00 15.38 ? 190 ASN B CB 1 ATOM 957 C CG . ASN A 1 134 ? 39.512 64.133 -34.066 1.00 27.53 ? 190 ASN B CG 1 ATOM 958 O OD1 . ASN A 1 134 ? 40.107 63.161 -34.526 1.00 33.39 ? 190 ASN B OD1 1 ATOM 959 N ND2 . ASN A 1 134 ? 38.532 64.021 -33.181 1.00 15.10 ? 190 ASN B ND2 1 ATOM 960 N N . LEU A 1 135 ? 39.114 67.868 -36.993 1.00 14.15 ? 191 LEU B N 1 ATOM 961 C CA . LEU A 1 135 ? 39.540 69.169 -37.476 1.00 13.98 ? 191 LEU B CA 1 ATOM 962 C C . LEU A 1 135 ? 38.650 70.267 -36.886 1.00 13.07 ? 191 LEU B C 1 ATOM 963 O O . LEU A 1 135 ? 37.417 70.214 -36.935 1.00 12.38 ? 191 LEU B O 1 ATOM 964 C CB . LEU A 1 135 ? 39.561 69.209 -39.003 1.00 14.02 ? 191 LEU B CB 1 ATOM 965 C CG . LEU A 1 135 ? 40.195 70.436 -39.665 1.00 14.01 ? 191 LEU B CG 1 ATOM 966 C CD1 . LEU A 1 135 ? 41.649 70.569 -39.246 1.00 14.86 ? 191 LEU B CD1 1 ATOM 967 C CD2 . LEU A 1 135 ? 40.060 70.391 -41.206 1.00 14.00 ? 191 LEU B CD2 1 ATOM 968 N N . GLN A 1 136 ? 39.308 71.245 -36.289 1.00 13.14 ? 192 GLN B N 1 ATOM 969 C CA . GLN A 1 136 ? 38.647 72.359 -35.644 1.00 12.39 ? 192 GLN B CA 1 ATOM 970 C C . GLN A 1 136 ? 38.789 73.616 -36.483 1.00 16.24 ? 192 GLN B C 1 ATOM 971 O O . GLN A 1 136 ? 37.798 74.312 -36.725 1.00 15.35 ? 192 GLN B O 1 ATOM 972 C CB . GLN A 1 136 ? 39.147 72.555 -34.219 1.00 12.63 ? 192 GLN B CB 1 ATOM 973 C CG . GLN A 1 136 ? 38.389 71.687 -33.233 1.00 12.44 ? 192 GLN B CG 1 ATOM 974 C CD . GLN A 1 136 ? 38.894 71.776 -31.800 1.00 12.73 ? 192 GLN B CD 1 ATOM 975 O OE1 . GLN A 1 136 ? 39.283 72.843 -31.319 1.00 26.47 ? 192 GLN B OE1 1 ATOM 976 N NE2 . GLN A 1 136 ? 38.858 70.647 -31.099 1.00 13.07 ? 192 GLN B NE2 1 ATOM 977 N N . VAL A 1 137 ? 40.042 73.941 -36.812 1.00 12.77 ? 193 VAL B N 1 ATOM 978 C CA . VAL A 1 137 ? 40.422 75.134 -37.559 1.00 26.42 ? 193 VAL B CA 1 ATOM 979 C C . VAL A 1 137 ? 41.145 74.786 -38.868 1.00 27.52 ? 193 VAL B C 1 ATOM 980 O O . VAL A 1 137 ? 42.171 74.088 -38.867 1.00 14.09 ? 193 VAL B O 1 ATOM 981 C CB . VAL A 1 137 ? 41.339 76.039 -36.697 1.00 16.30 ? 193 VAL B CB 1 ATOM 982 C CG1 . VAL A 1 137 ? 42.111 77.038 -37.558 1.00 17.78 ? 193 VAL B CG1 1 ATOM 983 C CG2 . VAL A 1 137 ? 40.530 76.763 -35.639 1.00 19.24 ? 193 VAL B CG2 1 ATOM 984 N N . LEU A 1 138 ? 40.588 75.255 -39.986 1.00 20.81 ? 194 LEU B N 1 ATOM 985 C CA . LEU A 1 138 ? 41.256 75.164 -41.278 1.00 13.23 ? 194 LEU B CA 1 ATOM 986 C C . LEU A 1 138 ? 41.402 76.585 -41.788 1.00 30.74 ? 194 LEU B C 1 ATOM 987 O O . LEU A 1 138 ? 40.402 77.246 -42.061 1.00 12.13 ? 194 LEU B O 1 ATOM 988 C CB . LEU A 1 138 ? 40.450 74.283 -42.267 1.00 14.74 ? 194 LEU B CB 1 ATOM 989 C CG . LEU A 1 138 ? 40.641 74.444 -43.807 1.00 17.33 ? 194 LEU B CG 1 ATOM 990 C CD1 . LEU A 1 138 ? 42.094 74.383 -44.218 1.00 19.20 ? 194 LEU B CD1 1 ATOM 991 C CD2 . LEU A 1 138 ? 39.863 73.420 -44.621 1.00 13.06 ? 194 LEU B CD2 1 ATOM 992 N N . ARG A 1 139 ? 42.635 77.083 -41.879 1.00 13.56 ? 195 ARG B N 1 ATOM 993 C CA . ARG A 1 139 ? 42.838 78.389 -42.507 1.00 19.45 ? 195 ARG B CA 1 ATOM 994 C C . ARG A 1 139 ? 43.895 78.314 -43.608 1.00 24.11 ? 195 ARG B C 1 ATOM 995 O O . ARG A 1 139 ? 45.100 78.224 -43.344 1.00 21.08 ? 195 ARG B O 1 ATOM 996 C CB . ARG A 1 139 ? 43.220 79.427 -41.454 1.00 13.29 ? 195 ARG B CB 1 ATOM 997 C CG . ARG A 1 139 ? 42.200 79.502 -40.299 1.00 24.06 ? 195 ARG B CG 1 ATOM 998 C CD . ARG A 1 139 ? 42.574 80.509 -39.220 1.00 14.25 ? 195 ARG B CD 1 ATOM 999 N NE . ARG A 1 139 ? 42.866 81.808 -39.800 1.00 21.06 ? 195 ARG B NE 1 ATOM 1000 C CZ . ARG A 1 139 ? 43.809 82.626 -39.344 1.00 25.28 ? 195 ARG B CZ 1 ATOM 1001 N NH1 . ARG A 1 139 ? 44.039 83.786 -39.953 1.00 25.80 ? 195 ARG B NH1 1 ATOM 1002 N NH2 . ARG A 1 139 ? 44.530 82.271 -38.290 1.00 18.29 ? 195 ARG B NH2 1 ATOM 1003 N N . ALA A 1 140 ? 43.391 78.318 -44.842 1.00 13.77 ? 196 ALA B N 1 ATOM 1004 C CA . ALA A 1 140 ? 44.172 78.303 -46.079 1.00 16.19 ? 196 ALA B CA 1 ATOM 1005 C C . ALA A 1 140 ? 44.152 79.612 -46.853 1.00 17.29 ? 196 ALA B C 1 ATOM 1006 O O . ALA A 1 140 ? 44.579 79.660 -48.010 1.00 15.96 ? 196 ALA B O 1 ATOM 1007 C CB . ALA A 1 140 ? 43.751 77.148 -46.967 1.00 19.97 ? 196 ALA B CB 1 ATOM 1008 N N . GLY A 1 141 ? 43.563 80.647 -46.270 1.00 20.03 ? 197 GLY B N 1 ATOM 1009 C CA . GLY A 1 141 ? 43.405 81.901 -46.978 1.00 17.94 ? 197 GLY B CA 1 ATOM 1010 C C . GLY A 1 141 ? 44.718 82.521 -47.419 1.00 14.13 ? 197 GLY B C 1 ATOM 1011 O O . GLY A 1 141 ? 45.796 82.064 -47.050 1.00 17.66 ? 197 GLY B O 1 ATOM 1012 N N . GLY A 1 142 ? 44.630 83.554 -48.244 1.00 18.59 ? 198 GLY B N 1 ATOM 1013 C CA . GLY A 1 142 ? 45.817 84.244 -48.701 1.00 21.58 ? 198 GLY B CA 1 ATOM 1014 C C . GLY A 1 142 ? 46.690 83.364 -49.575 1.00 23.34 ? 198 GLY B C 1 ATOM 1015 O O . GLY A 1 142 ? 47.922 83.476 -49.554 1.00 20.27 ? 198 GLY B O 1 ATOM 1016 N N . ASN A 1 143 ? 46.067 82.441 -50.303 1.00 21.65 ? 199 ASN B N 1 ATOM 1017 C CA . ASN A 1 143 ? 46.757 81.803 -51.416 1.00 20.66 ? 199 ASN B CA 1 ATOM 1018 C C . ASN A 1 143 ? 46.047 82.159 -52.714 1.00 21.79 ? 199 ASN B C 1 ATOM 1019 O O . ASN A 1 143 ? 44.993 81.594 -53.023 1.00 22.96 ? 199 ASN B O 1 ATOM 1020 C CB . ASN A 1 143 ? 46.815 80.288 -51.228 1.00 15.74 ? 199 ASN B CB 1 ATOM 1021 C CG . ASN A 1 143 ? 47.745 79.873 -50.089 1.00 29.63 ? 199 ASN B CG 1 ATOM 1022 O OD1 . ASN A 1 143 ? 48.949 79.753 -50.284 1.00 21.48 ? 199 ASN B OD1 1 ATOM 1023 N ND2 . ASN A 1 143 ? 47.187 79.639 -48.905 1.00 16.07 ? 199 ASN B ND2 1 ATOM 1024 N N . LYS A 1 144 ? 46.654 83.044 -53.500 1.00 15.00 ? 200 LYS B N 1 ATOM 1025 C CA . LYS A 1 144 ? 45.972 83.617 -54.657 1.00 19.62 ? 200 LYS B CA 1 ATOM 1026 C C . LYS A 1 144 ? 45.472 82.585 -55.649 1.00 24.74 ? 200 LYS B C 1 ATOM 1027 O O . LYS A 1 144 ? 44.429 82.782 -56.280 1.00 29.06 ? 200 LYS B O 1 ATOM 1028 C CB . LYS A 1 144 ? 46.839 84.651 -55.385 1.00 18.53 ? 200 LYS B CB 1 ATOM 1029 C CG . LYS A 1 144 ? 45.976 85.725 -56.020 1.00 26.79 ? 200 LYS B CG 1 ATOM 1030 C CD . LYS A 1 144 ? 46.678 86.504 -57.108 1.00 33.80 ? 200 LYS B CD 1 ATOM 1031 C CE . LYS A 1 144 ? 45.653 87.315 -57.901 1.00 38.73 ? 200 LYS B CE 1 ATOM 1032 N NZ . LYS A 1 144 ? 44.890 88.255 -57.023 1.00 41.08 ? 200 LYS B NZ 1 ATOM 1033 N N . ASN A 1 145 ? 46.222 81.497 -55.799 1.00 23.34 ? 201 ASN B N 1 ATOM 1034 C CA . ASN A 1 145 ? 45.885 80.463 -56.784 1.00 19.75 ? 201 ASN B CA 1 ATOM 1035 C C . ASN A 1 145 ? 45.161 79.212 -56.304 1.00 23.62 ? 201 ASN B C 1 ATOM 1036 O O . ASN A 1 145 ? 44.969 78.270 -57.082 1.00 24.63 ? 201 ASN B O 1 ATOM 1037 C CB . ASN A 1 145 ? 47.098 80.112 -57.628 1.00 17.91 ? 201 ASN B CB 1 ATOM 1038 C CG . ASN A 1 145 ? 47.490 81.249 -58.519 1.00 23.10 ? 201 ASN B CG 1 ATOM 1039 O OD1 . ASN A 1 145 ? 46.645 81.822 -59.215 1.00 30.61 ? 201 ASN B OD1 1 ATOM 1040 N ND2 . ASN A 1 145 ? 48.756 81.630 -58.469 1.00 25.46 ? 201 ASN B ND2 1 ATOM 1041 N N . LEU A 1 146 ? 44.793 79.190 -55.024 1.00 25.43 ? 202 LEU B N 1 ATOM 1042 C CA . LEU A 1 146 ? 43.987 78.104 -54.485 1.00 22.73 ? 202 LEU B CA 1 ATOM 1043 C C . LEU A 1 146 ? 42.641 78.245 -55.171 1.00 22.65 ? 202 LEU B C 1 ATOM 1044 O O . LEU A 1 146 ? 42.004 79.283 -55.060 1.00 27.17 ? 202 LEU B O 1 ATOM 1045 C CB . LEU A 1 146 ? 43.851 78.279 -52.974 1.00 27.02 ? 202 LEU B CB 1 ATOM 1046 C CG . LEU A 1 146 ? 43.460 77.096 -52.088 1.00 30.21 ? 202 LEU B CG 1 ATOM 1047 C CD1 . LEU A 1 146 ? 41.997 76.725 -52.281 1.00 37.84 ? 202 LEU B CD1 1 ATOM 1048 C CD2 . LEU A 1 146 ? 44.359 75.909 -52.373 1.00 26.97 ? 202 LEU B CD2 1 ATOM 1049 N N . ARG A 1 147 ? 42.212 77.204 -55.881 1.00 26.71 ? 203 ARG B N 1 ATOM 1050 C CA . ARG A 1 147 ? 41.071 77.325 -56.787 1.00 26.28 ? 203 ARG B CA 1 ATOM 1051 C C . ARG A 1 147 ? 40.090 76.180 -56.665 1.00 26.96 ? 203 ARG B C 1 ATOM 1052 O O . ARG A 1 147 ? 40.244 75.306 -55.814 1.00 30.34 ? 203 ARG B O 1 ATOM 1053 C CB . ARG A 1 147 ? 41.519 77.452 -58.247 1.00 25.50 ? 203 ARG B CB 1 ATOM 1054 C CG . ARG A 1 147 ? 42.203 76.213 -58.833 1.00 34.02 ? 203 ARG B CG 1 ATOM 1055 C CD . ARG A 1 147 ? 42.190 76.216 -60.381 1.00 36.91 ? 203 ARG B CD 1 ATOM 1056 N NE . ARG A 1 147 ? 40.820 76.228 -60.894 1.00 42.51 ? 203 ARG B NE 1 ATOM 1057 C CZ . ARG A 1 147 ? 40.050 75.146 -61.010 1.00 41.47 ? 203 ARG B CZ 1 ATOM 1058 N NH1 . ARG A 1 147 ? 40.511 73.945 -60.667 1.00 44.61 ? 203 ARG B NH1 1 ATOM 1059 N NH2 . ARG A 1 147 ? 38.812 75.266 -61.465 1.00 35.61 ? 203 ARG B NH2 1 ATOM 1060 N N . GLY A 1 148 ? 39.077 76.194 -57.525 1.00 23.65 ? 204 GLY B N 1 ATOM 1061 C CA . GLY A 1 148 ? 38.042 75.186 -57.469 1.00 24.88 ? 204 GLY B CA 1 ATOM 1062 C C . GLY A 1 148 ? 36.961 75.483 -56.449 1.00 27.32 ? 204 GLY B C 1 ATOM 1063 O O . GLY A 1 148 ? 36.985 76.512 -55.769 1.00 32.44 ? 204 GLY B O 1 ATOM 1064 N N . GLU A 1 149 ? 35.986 74.586 -56.372 1.00 21.59 ? 205 GLU B N 1 ATOM 1065 C CA . GLU A 1 149 ? 34.877 74.741 -55.457 1.00 17.14 ? 205 GLU B CA 1 ATOM 1066 C C . GLU A 1 149 ? 35.296 74.244 -54.088 1.00 22.16 ? 205 GLU B C 1 ATOM 1067 O O . GLU A 1 149 ? 36.172 73.392 -53.983 1.00 21.38 ? 205 GLU B O 1 ATOM 1068 C CB . GLU A 1 149 ? 33.648 73.977 -55.956 1.00 15.87 ? 205 GLU B CB 1 ATOM 1069 C CG . GLU A 1 149 ? 33.206 74.341 -57.366 1.00 21.97 ? 205 GLU B CG 1 ATOM 1070 C CD . GLU A 1 149 ? 31.722 74.121 -57.569 1.00 44.60 ? 205 GLU B CD 1 ATOM 1071 O OE1 . GLU A 1 149 ? 31.256 74.130 -58.732 1.00 48.58 ? 205 GLU B OE1 1 ATOM 1072 O OE2 . GLU A 1 149 ? 31.013 73.951 -56.551 1.00 58.81 ? 205 GLU B OE2 1 ATOM 1073 N N . LEU A 1 150 ? 34.696 74.788 -53.036 1.00 25.51 ? 206 LEU B N 1 ATOM 1074 C CA . LEU A 1 150 ? 34.899 74.207 -51.722 1.00 24.92 ? 206 LEU B CA 1 ATOM 1075 C C . LEU A 1 150 ? 34.267 72.835 -51.846 1.00 27.87 ? 206 LEU B C 1 ATOM 1076 O O . LEU A 1 150 ? 33.136 72.724 -52.312 1.00 27.94 ? 206 LEU B O 1 ATOM 1077 C CB . LEU A 1 150 ? 34.218 75.044 -50.638 1.00 22.02 ? 206 LEU B CB 1 ATOM 1078 C CG . LEU A 1 150 ? 34.332 74.478 -49.229 1.00 31.09 ? 206 LEU B CG 1 ATOM 1079 C CD1 . LEU A 1 150 ? 35.795 74.455 -48.771 1.00 33.04 ? 206 LEU B CD1 1 ATOM 1080 C CD2 . LEU A 1 150 ? 33.439 75.241 -48.235 1.00 30.21 ? 206 LEU B CD2 1 ATOM 1081 N N . PRO A 1 151 ? 35.016 71.774 -51.512 1.00 27.68 ? 207 PRO B N 1 ATOM 1082 C CA . PRO A 1 151 ? 34.469 70.426 -51.675 1.00 15.32 ? 207 PRO B CA 1 ATOM 1083 C C . PRO A 1 151 ? 33.267 70.125 -50.769 1.00 22.62 ? 207 PRO B C 1 ATOM 1084 O O . PRO A 1 151 ? 33.229 70.540 -49.609 1.00 25.83 ? 207 PRO B O 1 ATOM 1085 C CB . PRO A 1 151 ? 35.658 69.523 -51.326 1.00 17.26 ? 207 PRO B CB 1 ATOM 1086 C CG . PRO A 1 151 ? 36.623 70.385 -50.605 1.00 12.73 ? 207 PRO B CG 1 ATOM 1087 C CD . PRO A 1 151 ? 36.446 71.747 -51.163 1.00 26.41 ? 207 PRO B CD 1 ATOM 1088 N N . TRP A 1 152 ? 32.301 69.404 -51.326 1.00 11.07 ? 208 TRP B N 1 ATOM 1089 C CA . TRP A 1 152 ? 31.160 68.843 -50.610 1.00 20.58 ? 208 TRP B CA 1 ATOM 1090 C C . TRP A 1 152 ? 31.564 68.120 -49.319 1.00 25.76 ? 208 TRP B C 1 ATOM 1091 O O . TRP A 1 152 ? 30.926 68.273 -48.265 1.00 23.27 ? 208 TRP B O 1 ATOM 1092 C CB . TRP A 1 152 ? 30.458 67.853 -51.531 1.00 21.67 ? 208 TRP B CB 1 ATOM 1093 C CG . TRP A 1 152 ? 29.301 67.160 -50.916 1.00 34.43 ? 208 TRP B CG 1 ATOM 1094 C CD1 . TRP A 1 152 ? 29.311 65.956 -50.272 1.00 41.33 ? 208 TRP B CD1 1 ATOM 1095 C CD2 . TRP A 1 152 ? 27.946 67.612 -50.903 1.00 36.95 ? 208 TRP B CD2 1 ATOM 1096 N NE1 . TRP A 1 152 ? 28.045 65.638 -49.847 1.00 43.04 ? 208 TRP B NE1 1 ATOM 1097 C CE2 . TRP A 1 152 ? 27.187 66.641 -50.222 1.00 39.80 ? 208 TRP B CE2 1 ATOM 1098 C CE3 . TRP A 1 152 ? 27.298 68.751 -51.392 1.00 36.50 ? 208 TRP B CE3 1 ATOM 1099 C CZ2 . TRP A 1 152 ? 25.816 66.774 -50.017 1.00 36.42 ? 208 TRP B CZ2 1 ATOM 1100 C CZ3 . TRP A 1 152 ? 25.933 68.880 -51.189 1.00 34.76 ? 208 TRP B CZ3 1 ATOM 1101 C CH2 . TRP A 1 152 ? 25.209 67.901 -50.508 1.00 31.58 ? 208 TRP B CH2 1 ATOM 1102 N N . GLU A 1 153 ? 32.645 67.350 -49.398 1.00 23.08 ? 209 GLU B N 1 ATOM 1103 C CA . GLU A 1 153 ? 33.138 66.610 -48.239 1.00 18.77 ? 209 GLU B CA 1 ATOM 1104 C C . GLU A 1 153 ? 33.480 67.481 -47.024 1.00 22.33 ? 209 GLU B C 1 ATOM 1105 O O . GLU A 1 153 ? 33.625 66.962 -45.919 1.00 22.98 ? 209 GLU B O 1 ATOM 1106 C CB . GLU A 1 153 ? 34.347 65.760 -48.610 1.00 18.87 ? 209 GLU B CB 1 ATOM 1107 C CG . GLU A 1 153 ? 33.991 64.501 -49.385 1.00 22.40 ? 209 GLU B CG 1 ATOM 1108 C CD . GLU A 1 153 ? 33.668 64.770 -50.837 1.00 26.61 ? 209 GLU B CD 1 ATOM 1109 O OE1 . GLU A 1 153 ? 33.850 65.921 -51.293 1.00 23.40 ? 209 GLU B OE1 1 ATOM 1110 O OE2 . GLU A 1 153 ? 33.233 63.822 -51.516 1.00 30.43 ? 209 GLU B OE2 1 ATOM 1111 N N . ILE A 1 154 ? 33.606 68.794 -47.208 1.00 17.40 ? 210 ILE B N 1 ATOM 1112 C CA . ILE A 1 154 ? 33.863 69.663 -46.062 1.00 15.12 ? 210 ILE B CA 1 ATOM 1113 C C . ILE A 1 154 ? 32.754 69.508 -45.031 1.00 18.88 ? 210 ILE B C 1 ATOM 1114 O O . ILE A 1 154 ? 32.960 69.783 -43.859 1.00 26.64 ? 210 ILE B O 1 ATOM 1115 C CB . ILE A 1 154 ? 33.993 71.161 -46.441 1.00 28.97 ? 210 ILE B CB 1 ATOM 1116 C CG1 . ILE A 1 154 ? 34.565 71.959 -45.267 1.00 10.72 ? 210 ILE B CG1 1 ATOM 1117 C CG2 . ILE A 1 154 ? 32.639 71.758 -46.836 1.00 22.13 ? 210 ILE B CG2 1 ATOM 1118 C CD1 . ILE A 1 154 ? 36.033 71.775 -45.062 1.00 11.50 ? 210 ILE B CD1 1 ATOM 1119 N N . GLY A 1 155 ? 31.578 69.061 -45.462 1.00 17.61 ? 211 GLY B N 1 ATOM 1120 C CA . GLY A 1 155 ? 30.480 68.863 -44.531 1.00 16.94 ? 211 GLY B CA 1 ATOM 1121 C C . GLY A 1 155 ? 30.773 67.795 -43.485 1.00 22.52 ? 211 GLY B C 1 ATOM 1122 O O . GLY A 1 155 ? 30.132 67.744 -42.439 1.00 27.09 ? 211 GLY B O 1 ATOM 1123 N N . ASN A 1 156 ? 31.748 66.939 -43.759 1.00 23.13 ? 212 ASN B N 1 ATOM 1124 C CA . ASN A 1 156 ? 32.043 65.832 -42.857 1.00 21.36 ? 212 ASN B CA 1 ATOM 1125 C C . ASN A 1 156 ? 32.989 66.210 -41.726 1.00 21.33 ? 212 ASN B C 1 ATOM 1126 O O . ASN A 1 156 ? 33.198 65.421 -40.801 1.00 27.40 ? 212 ASN B O 1 ATOM 1127 C CB . ASN A 1 156 ? 32.567 64.614 -43.618 1.00 22.74 ? 212 ASN B CB 1 ATOM 1128 C CG . ASN A 1 156 ? 31.571 64.100 -44.641 1.00 31.80 ? 212 ASN B CG 1 ATOM 1129 O OD1 . ASN A 1 156 ? 30.403 63.878 -44.325 1.00 36.17 ? 212 ASN B OD1 1 ATOM 1130 N ND2 . ASN A 1 156 ? 32.022 63.929 -45.880 1.00 33.57 ? 212 ASN B ND2 1 ATOM 1131 N N . CYS A 1 157 ? 33.533 67.421 -41.752 1.00 14.57 ? 213 CYS B N 1 ATOM 1132 C CA . CYS A 1 157 ? 34.356 67.793 -40.618 1.00 20.15 ? 213 CYS B CA 1 ATOM 1133 C C . CYS A 1 157 ? 33.423 68.461 -39.621 1.00 19.80 ? 213 CYS B C 1 ATOM 1134 O O . CYS A 1 157 ? 33.260 69.673 -39.634 1.00 18.72 ? 213 CYS B O 1 ATOM 1135 C CB . CYS A 1 157 ? 35.413 68.803 -41.077 1.00 15.83 ? 213 CYS B CB 1 ATOM 1136 S SG . CYS A 1 157 ? 36.475 68.219 -42.428 1.00 25.76 ? 213 CYS B SG 1 ATOM 1137 N N . GLU A 1 158 ? 32.948 67.695 -38.650 1.00 20.64 ? 214 GLU B N 1 ATOM 1138 C CA . GLU A 1 158 ? 31.821 68.159 -37.845 1.00 27.87 ? 214 GLU B CA 1 ATOM 1139 C C . GLU A 1 158 ? 32.250 68.860 -36.570 1.00 21.12 ? 214 GLU B C 1 ATOM 1140 O O . GLU A 1 158 ? 31.426 69.364 -35.825 1.00 29.42 ? 214 GLU B O 1 ATOM 1141 C CB . GLU A 1 158 ? 30.843 67.018 -37.555 1.00 45.47 ? 214 GLU B CB 1 ATOM 1142 C CG . GLU A 1 158 ? 30.014 66.600 -38.779 1.00 55.57 ? 214 GLU B CG 1 ATOM 1143 C CD . GLU A 1 158 ? 29.011 65.491 -38.480 1.00 60.07 ? 214 GLU B CD 1 ATOM 1144 O OE1 . GLU A 1 158 ? 28.750 65.201 -37.290 1.00 61.31 ? 214 GLU B OE1 1 ATOM 1145 O OE2 . GLU A 1 158 ? 28.482 64.905 -39.446 1.00 62.37 ? 214 GLU B OE2 1 ATOM 1146 N N . ASN A 1 159 ? 33.550 68.900 -36.339 1.00 18.27 ? 215 ASN B N 1 ATOM 1147 C CA . ASN A 1 159 ? 34.100 69.688 -35.264 1.00 10.70 ? 215 ASN B CA 1 ATOM 1148 C C . ASN A 1 159 ? 34.593 71.065 -35.718 1.00 10.53 ? 215 ASN B C 1 ATOM 1149 O O . ASN A 1 159 ? 35.121 71.816 -34.910 1.00 24.80 ? 215 ASN B O 1 ATOM 1150 C CB . ASN A 1 159 ? 35.255 68.926 -34.611 1.00 24.43 ? 215 ASN B CB 1 ATOM 1151 C CG . ASN A 1 159 ? 34.780 67.788 -33.703 1.00 27.21 ? 215 ASN B CG 1 ATOM 1152 O OD1 . ASN A 1 159 ? 33.594 67.459 -33.656 1.00 23.75 ? 215 ASN B OD1 1 ATOM 1153 N ND2 . ASN A 1 159 ? 35.716 67.182 -32.984 1.00 31.97 ? 215 ASN B ND2 1 ATOM 1154 N N . LEU A 1 160 ? 34.450 71.389 -37.000 1.00 10.39 ? 216 LEU B N 1 ATOM 1155 C CA . LEU A 1 160 ? 35.007 72.639 -37.516 1.00 10.31 ? 216 LEU B CA 1 ATOM 1156 C C . LEU A 1 160 ? 34.416 73.825 -36.783 1.00 10.30 ? 216 LEU B C 1 ATOM 1157 O O . LEU A 1 160 ? 33.204 73.966 -36.681 1.00 8.96 ? 216 LEU B O 1 ATOM 1158 C CB . LEU A 1 160 ? 34.734 72.803 -39.021 1.00 10.17 ? 216 LEU B CB 1 ATOM 1159 C CG . LEU A 1 160 ? 35.909 72.629 -39.989 1.00 17.22 ? 216 LEU B CG 1 ATOM 1160 C CD1 . LEU A 1 160 ? 35.465 72.934 -41.410 1.00 16.77 ? 216 LEU B CD1 1 ATOM 1161 C CD2 . LEU A 1 160 ? 37.088 73.485 -39.613 1.00 11.24 ? 216 LEU B CD2 1 ATOM 1162 N N . VAL A 1 161 ? 35.272 74.638 -36.195 1.00 9.81 ? 217 VAL B N 1 ATOM 1163 C CA . VAL A 1 161 ? 34.776 75.867 -35.622 1.00 22.01 ? 217 VAL B CA 1 ATOM 1164 C C . VAL A 1 161 ? 35.140 77.113 -36.442 1.00 17.09 ? 217 VAL B C 1 ATOM 1165 O O . VAL A 1 161 ? 34.475 78.150 -36.356 1.00 8.40 ? 217 VAL B O 1 ATOM 1166 C CB . VAL A 1 161 ? 35.268 75.982 -34.152 1.00 9.38 ? 217 VAL B CB 1 ATOM 1167 C CG1 . VAL A 1 161 ? 36.704 76.451 -34.104 1.00 10.05 ? 217 VAL B CG1 1 ATOM 1168 C CG2 . VAL A 1 161 ? 34.406 76.909 -33.394 1.00 28.02 ? 217 VAL B CG2 1 ATOM 1169 N N . MET A 1 162 ? 36.169 76.980 -37.275 1.00 14.51 ? 218 MET B N 1 ATOM 1170 C CA . MET A 1 162 ? 36.713 78.109 -38.024 1.00 14.40 ? 218 MET B CA 1 ATOM 1171 C C . MET A 1 162 ? 37.125 77.638 -39.408 1.00 14.44 ? 218 MET B C 1 ATOM 1172 O O . MET A 1 162 ? 37.896 76.677 -39.538 1.00 10.75 ? 218 MET B O 1 ATOM 1173 C CB . MET A 1 162 ? 37.928 78.714 -37.291 1.00 14.58 ? 218 MET B CB 1 ATOM 1174 C CG . MET A 1 162 ? 38.864 79.586 -38.184 1.00 26.13 ? 218 MET B CG 1 ATOM 1175 S SD . MET A 1 162 ? 38.224 81.217 -38.673 1.00 24.51 ? 218 MET B SD 1 ATOM 1176 C CE . MET A 1 162 ? 39.298 81.668 -40.010 1.00 22.92 ? 218 MET B CE 1 ATOM 1177 N N . LEU A 1 163 ? 36.620 78.311 -40.434 1.00 9.62 ? 219 LEU B N 1 ATOM 1178 C CA . LEU A 1 163 ? 37.016 78.027 -41.810 1.00 9.96 ? 219 LEU B CA 1 ATOM 1179 C C . LEU A 1 163 ? 37.353 79.338 -42.487 1.00 16.49 ? 219 LEU B C 1 ATOM 1180 O O . LEU A 1 163 ? 36.477 80.179 -42.690 1.00 9.12 ? 219 LEU B O 1 ATOM 1181 C CB . LEU A 1 163 ? 35.879 77.337 -42.584 1.00 20.62 ? 219 LEU B CB 1 ATOM 1182 C CG . LEU A 1 163 ? 35.956 77.196 -44.135 1.00 25.97 ? 219 LEU B CG 1 ATOM 1183 C CD1 . LEU A 1 163 ? 36.931 76.126 -44.582 1.00 10.60 ? 219 LEU B CD1 1 ATOM 1184 C CD2 . LEU A 1 163 ? 34.627 76.876 -44.747 1.00 9.21 ? 219 LEU B CD2 1 ATOM 1185 N N . GLY A 1 164 ? 38.602 79.519 -42.894 1.00 10.48 ? 220 GLY B N 1 ATOM 1186 C CA . GLY A 1 164 ? 38.778 80.605 -43.813 1.00 10.32 ? 220 GLY B CA 1 ATOM 1187 C C . GLY A 1 164 ? 39.768 80.376 -44.912 1.00 11.00 ? 220 GLY B C 1 ATOM 1188 O O . GLY A 1 164 ? 40.897 79.914 -44.774 1.00 19.73 ? 220 GLY B O 1 ATOM 1189 N N . LEU A 1 165 ? 39.194 80.722 -46.056 1.00 14.20 ? 221 LEU B N 1 ATOM 1190 C CA . LEU A 1 165 ? 39.698 80.628 -47.414 1.00 11.01 ? 221 LEU B CA 1 ATOM 1191 C C . LEU A 1 165 ? 39.885 81.974 -48.098 1.00 11.54 ? 221 LEU B C 1 ATOM 1192 O O . LEU A 1 165 ? 39.763 82.041 -49.311 1.00 11.65 ? 221 LEU B O 1 ATOM 1193 C CB . LEU A 1 165 ? 38.862 79.640 -48.221 1.00 10.86 ? 221 LEU B CB 1 ATOM 1194 C CG . LEU A 1 165 ? 38.907 78.272 -47.513 1.00 14.44 ? 221 LEU B CG 1 ATOM 1195 C CD1 . LEU A 1 165 ? 37.769 77.343 -47.893 1.00 10.90 ? 221 LEU B CD1 1 ATOM 1196 C CD2 . LEU A 1 165 ? 40.245 77.598 -47.759 1.00 13.38 ? 221 LEU B CD2 1 ATOM 1197 N N . ALA A 1 166 ? 39.941 83.057 -47.333 1.00 10.51 ? 222 ALA B N 1 ATOM 1198 C CA . ALA A 1 166 ? 39.878 84.412 -47.898 1.00 13.95 ? 222 ALA B CA 1 ATOM 1199 C C . ALA A 1 166 ? 41.031 84.753 -48.844 1.00 10.80 ? 222 ALA B C 1 ATOM 1200 O O . ALA A 1 166 ? 42.095 84.146 -48.774 1.00 11.81 ? 222 ALA B O 1 ATOM 1201 C CB . ALA A 1 166 ? 39.792 85.443 -46.774 1.00 16.11 ? 222 ALA B CB 1 ATOM 1202 N N . GLU A 1 167 ? 40.808 85.716 -49.737 1.00 18.66 ? 223 GLU B N 1 ATOM 1203 C CA . GLU A 1 167 ? 41.797 86.071 -50.764 1.00 17.30 ? 223 GLU B CA 1 ATOM 1204 C C . GLU A 1 167 ? 42.350 84.847 -51.494 1.00 20.30 ? 223 GLU B C 1 ATOM 1205 O O . GLU A 1 167 ? 43.556 84.641 -51.555 1.00 22.84 ? 223 GLU B O 1 ATOM 1206 C CB . GLU A 1 167 ? 42.930 86.926 -50.186 1.00 11.49 ? 223 GLU B CB 1 ATOM 1207 C CG . GLU A 1 167 ? 42.426 88.261 -49.639 1.00 19.89 ? 223 GLU B CG 1 ATOM 1208 C CD . GLU A 1 167 ? 43.517 89.297 -49.440 1.00 21.23 ? 223 GLU B CD 1 ATOM 1209 O OE1 . GLU A 1 167 ? 44.502 89.292 -50.201 1.00 31.71 ? 223 GLU B OE1 1 ATOM 1210 O OE2 . GLU A 1 167 ? 43.391 90.122 -48.509 1.00 25.99 ? 223 GLU B OE2 1 ATOM 1211 N N . THR A 1 168 ? 41.449 84.017 -52.007 1.00 12.08 ? 224 THR B N 1 ATOM 1212 C CA . THR A 1 168 ? 41.837 82.886 -52.818 1.00 12.04 ? 224 THR B CA 1 ATOM 1213 C C . THR A 1 168 ? 41.040 82.941 -54.118 1.00 15.89 ? 224 THR B C 1 ATOM 1214 O O . THR A 1 168 ? 40.289 83.885 -54.357 1.00 14.65 ? 224 THR B O 1 ATOM 1215 C CB . THR A 1 168 ? 41.587 81.538 -52.102 1.00 12.15 ? 224 THR B CB 1 ATOM 1216 O OG1 . THR A 1 168 ? 40.208 81.434 -51.747 1.00 11.50 ? 224 THR B OG1 1 ATOM 1217 C CG2 . THR A 1 168 ? 42.410 81.434 -50.854 1.00 12.58 ? 224 THR B CG2 1 ATOM 1218 N N . SER A 1 169 ? 41.255 81.960 -54.983 1.00 13.49 ? 225 SER B N 1 ATOM 1219 C CA . SER A 1 169 ? 40.491 81.833 -56.221 1.00 15.88 ? 225 SER B CA 1 ATOM 1220 C C . SER A 1 169 ? 39.335 80.846 -56.113 1.00 14.11 ? 225 SER B C 1 ATOM 1221 O O . SER A 1 169 ? 38.777 80.424 -57.120 1.00 21.21 ? 225 SER B O 1 ATOM 1222 C CB . SER A 1 169 ? 41.396 81.551 -57.406 1.00 14.90 ? 225 SER B CB 1 ATOM 1223 O OG . SER A 1 169 ? 42.276 82.649 -57.568 1.00 16.40 ? 225 SER B OG 1 ATOM 1224 N N . LEU A 1 170 ? 39.043 80.432 -54.887 1.00 11.26 ? 226 LEU B N 1 ATOM 1225 C CA . LEU A 1 170 ? 37.918 79.551 -54.605 1.00 18.75 ? 226 LEU B CA 1 ATOM 1226 C C . LEU A 1 170 ? 36.693 80.108 -55.297 1.00 17.04 ? 226 LEU B C 1 ATOM 1227 O O . LEU A 1 170 ? 36.441 81.314 -55.261 1.00 19.69 ? 226 LEU B O 1 ATOM 1228 C CB . LEU A 1 170 ? 37.669 79.486 -53.096 1.00 16.76 ? 226 LEU B CB 1 ATOM 1229 C CG . LEU A 1 170 ? 37.035 78.191 -52.578 1.00 28.18 ? 226 LEU B CG 1 ATOM 1230 C CD1 . LEU A 1 170 ? 37.976 76.994 -52.735 1.00 26.73 ? 226 LEU B CD1 1 ATOM 1231 C CD2 . LEU A 1 170 ? 36.623 78.352 -51.128 1.00 30.53 ? 226 LEU B CD2 1 ATOM 1232 N N . SER A 1 171 ? 35.945 79.235 -55.953 1.00 19.12 ? 227 SER B N 1 ATOM 1233 C CA . SER A 1 171 ? 34.901 79.691 -56.855 1.00 21.29 ? 227 SER B CA 1 ATOM 1234 C C . SER A 1 171 ? 33.649 78.844 -56.758 1.00 21.01 ? 227 SER B C 1 ATOM 1235 O O . SER A 1 171 ? 33.533 77.978 -55.895 1.00 29.97 ? 227 SER B O 1 ATOM 1236 C CB . SER A 1 171 ? 35.404 79.645 -58.295 1.00 23.48 ? 227 SER B CB 1 ATOM 1237 O OG . SER A 1 171 ? 35.781 78.326 -58.640 1.00 24.33 ? 227 SER B OG 1 ATOM 1238 N N . GLY A 1 172 ? 32.715 79.097 -57.666 1.00 17.55 ? 228 GLY B N 1 ATOM 1239 C CA . GLY A 1 172 ? 31.461 78.373 -57.672 1.00 15.61 ? 228 GLY B CA 1 ATOM 1240 C C . GLY A 1 172 ? 30.621 78.711 -56.460 1.00 18.64 ? 228 GLY B C 1 ATOM 1241 O O . GLY A 1 172 ? 30.796 79.753 -55.836 1.00 25.58 ? 228 GLY B O 1 ATOM 1242 N N . LYS A 1 173 ? 29.712 77.810 -56.122 1.00 14.45 ? 229 LYS B N 1 ATOM 1243 C CA . LYS A 1 173 ? 28.787 78.034 -55.037 1.00 14.84 ? 229 LYS B CA 1 ATOM 1244 C C . LYS A 1 173 ? 29.170 77.183 -53.826 1.00 21.46 ? 229 LYS B C 1 ATOM 1245 O O . LYS A 1 173 ? 29.708 76.082 -53.961 1.00 30.54 ? 229 LYS B O 1 ATOM 1246 C CB . LYS A 1 173 ? 27.361 77.716 -55.500 1.00 13.98 ? 229 LYS B CB 1 ATOM 1247 C CG . LYS A 1 173 ? 27.048 76.238 -55.551 1.00 21.93 ? 229 LYS B CG 1 ATOM 1248 C CD . LYS A 1 173 ? 25.607 75.980 -55.950 1.00 36.33 ? 229 LYS B CD 1 ATOM 1249 C CE . LYS A 1 173 ? 25.413 76.065 -57.453 1.00 44.84 ? 229 LYS B CE 1 ATOM 1250 N NZ . LYS A 1 173 ? 25.273 77.465 -57.937 1.00 51.40 ? 229 LYS B NZ 1 ATOM 1251 N N . LEU A 1 174 ? 28.911 77.717 -52.641 1.00 20.07 ? 230 LEU B N 1 ATOM 1252 C CA . LEU A 1 174 ? 29.118 76.984 -51.403 1.00 15.47 ? 230 LEU B CA 1 ATOM 1253 C C . LEU A 1 174 ? 28.162 75.805 -51.355 1.00 15.08 ? 230 LEU B C 1 ATOM 1254 O O . LEU A 1 174 ? 26.976 75.956 -51.612 1.00 26.15 ? 230 LEU B O 1 ATOM 1255 C CB . LEU A 1 174 ? 28.866 77.900 -50.214 1.00 19.59 ? 230 LEU B CB 1 ATOM 1256 C CG . LEU A 1 174 ? 29.878 79.017 -49.955 1.00 16.02 ? 230 LEU B CG 1 ATOM 1257 C CD1 . LEU A 1 174 ? 29.485 79.753 -48.701 1.00 15.88 ? 230 LEU B CD1 1 ATOM 1258 C CD2 . LEU A 1 174 ? 31.265 78.423 -49.790 1.00 17.60 ? 230 LEU B CD2 1 ATOM 1259 N N . PRO A 1 175 ? 28.675 74.621 -51.020 1.00 15.78 ? 231 PRO B N 1 ATOM 1260 C CA . PRO A 1 175 ? 27.845 73.415 -51.075 1.00 15.13 ? 231 PRO B CA 1 ATOM 1261 C C . PRO A 1 175 ? 26.845 73.342 -49.917 1.00 16.33 ? 231 PRO B C 1 ATOM 1262 O O . PRO A 1 175 ? 27.142 73.776 -48.809 1.00 10.64 ? 231 PRO B O 1 ATOM 1263 C CB . PRO A 1 175 ? 28.869 72.300 -50.918 1.00 14.55 ? 231 PRO B CB 1 ATOM 1264 C CG . PRO A 1 175 ? 29.910 72.915 -49.990 1.00 11.21 ? 231 PRO B CG 1 ATOM 1265 C CD . PRO A 1 175 ? 30.005 74.359 -50.436 1.00 14.69 ? 231 PRO B CD 1 ATOM 1266 N N . ALA A 1 176 ? 25.682 72.764 -50.184 1.00 17.24 ? 232 ALA B N 1 ATOM 1267 C CA . ALA A 1 176 ? 24.659 72.539 -49.176 1.00 14.72 ? 232 ALA B CA 1 ATOM 1268 C C . ALA A 1 176 ? 25.224 71.768 -47.984 1.00 17.45 ? 232 ALA B C 1 ATOM 1269 O O . ALA A 1 176 ? 24.728 71.882 -46.869 1.00 23.98 ? 232 ALA B O 1 ATOM 1270 C CB . ALA A 1 176 ? 23.492 71.780 -49.796 1.00 7.60 ? 232 ALA B CB 1 ATOM 1271 N N . SER A 1 177 ? 26.281 71.005 -48.233 1.00 16.74 ? 233 SER B N 1 ATOM 1272 C CA . SER A 1 177 ? 27.024 70.292 -47.196 1.00 14.25 ? 233 SER B CA 1 ATOM 1273 C C . SER A 1 177 ? 27.390 71.170 -46.011 1.00 18.47 ? 233 SER B C 1 ATOM 1274 O O . SER A 1 177 ? 27.464 70.700 -44.883 1.00 17.62 ? 233 SER B O 1 ATOM 1275 C CB . SER A 1 177 ? 28.333 69.803 -47.789 1.00 19.39 ? 233 SER B CB 1 ATOM 1276 O OG . SER A 1 177 ? 28.253 68.434 -48.090 1.00 39.64 ? 233 SER B OG 1 ATOM 1277 N N . ILE A 1 178 ? 27.657 72.442 -46.284 1.00 14.99 ? 234 ILE B N 1 ATOM 1278 C CA . ILE A 1 178 ? 28.045 73.390 -45.261 1.00 9.50 ? 234 ILE B CA 1 ATOM 1279 C C . ILE A 1 178 ? 27.044 73.374 -44.097 1.00 11.56 ? 234 ILE B C 1 ATOM 1280 O O . ILE A 1 178 ? 27.415 73.647 -42.959 1.00 16.20 ? 234 ILE B O 1 ATOM 1281 C CB . ILE A 1 178 ? 28.193 74.816 -45.869 1.00 28.11 ? 234 ILE B CB 1 ATOM 1282 C CG1 . ILE A 1 178 ? 29.279 75.609 -45.156 1.00 30.45 ? 234 ILE B CG1 1 ATOM 1283 C CG2 . ILE A 1 178 ? 26.876 75.575 -45.848 1.00 24.12 ? 234 ILE B CG2 1 ATOM 1284 C CD1 . ILE A 1 178 ? 30.639 75.057 -45.355 1.00 33.65 ? 234 ILE B CD1 1 ATOM 1285 N N . GLY A 1 179 ? 25.788 73.012 -44.371 1.00 15.47 ? 235 GLY B N 1 ATOM 1286 C CA . GLY A 1 179 ? 24.751 72.962 -43.341 1.00 11.78 ? 235 GLY B CA 1 ATOM 1287 C C . GLY A 1 179 ? 24.957 71.874 -42.283 1.00 19.58 ? 235 GLY B C 1 ATOM 1288 O O . GLY A 1 179 ? 24.253 71.816 -41.277 1.00 17.72 ? 235 GLY B O 1 ATOM 1289 N N . ASN A 1 180 ? 25.920 70.995 -42.517 1.00 18.13 ? 236 ASN B N 1 ATOM 1290 C CA . ASN A 1 180 ? 26.233 69.936 -41.580 1.00 26.27 ? 236 ASN B CA 1 ATOM 1291 C C . ASN A 1 180 ? 27.271 70.356 -40.556 1.00 27.21 ? 236 ASN B C 1 ATOM 1292 O O . ASN A 1 180 ? 27.540 69.627 -39.606 1.00 24.65 ? 236 ASN B O 1 ATOM 1293 C CB . ASN A 1 180 ? 26.693 68.681 -42.317 1.00 30.45 ? 236 ASN B CB 1 ATOM 1294 C CG . ASN A 1 180 ? 25.535 67.827 -42.753 1.00 42.69 ? 236 ASN B CG 1 ATOM 1295 O OD1 . ASN A 1 180 ? 25.354 67.550 -43.942 1.00 38.10 ? 236 ASN B OD1 1 ATOM 1296 N ND2 . ASN A 1 180 ? 24.719 67.412 -41.783 1.00 52.27 ? 236 ASN B ND2 1 ATOM 1297 N N . LEU A 1 181 ? 27.827 71.552 -40.710 1.00 24.26 ? 237 LEU B N 1 ATOM 1298 C CA . LEU A 1 181 ? 28.811 71.961 -39.737 1.00 18.71 ? 237 LEU B CA 1 ATOM 1299 C C . LEU A 1 181 ? 27.997 72.648 -38.667 1.00 17.27 ? 237 LEU B C 1 ATOM 1300 O O . LEU A 1 181 ? 27.679 73.831 -38.766 1.00 25.57 ? 237 LEU B O 1 ATOM 1301 C CB . LEU A 1 181 ? 29.780 72.964 -40.380 1.00 17.50 ? 237 LEU B CB 1 ATOM 1302 C CG . LEU A 1 181 ? 30.541 72.516 -41.641 1.00 20.32 ? 237 LEU B CG 1 ATOM 1303 C CD1 . LEU A 1 181 ? 31.417 73.634 -42.174 1.00 8.51 ? 237 LEU B CD1 1 ATOM 1304 C CD2 . LEU A 1 181 ? 31.387 71.284 -41.352 1.00 9.17 ? 237 LEU B CD2 1 ATOM 1305 N N . LYS A 1 182 ? 27.740 71.916 -37.595 1.00 17.53 ? 238 LYS B N 1 ATOM 1306 C CA . LYS A 1 182 ? 26.842 72.391 -36.554 1.00 20.88 ? 238 LYS B CA 1 ATOM 1307 C C . LYS A 1 182 ? 27.624 73.090 -35.481 1.00 13.80 ? 238 LYS B C 1 ATOM 1308 O O . LYS A 1 182 ? 27.050 73.696 -34.585 1.00 26.13 ? 238 LYS B O 1 ATOM 1309 C CB . LYS A 1 182 ? 26.063 71.222 -35.935 1.00 30.31 ? 238 LYS B CB 1 ATOM 1310 C CG . LYS A 1 182 ? 24.636 71.048 -36.460 1.00 29.07 ? 238 LYS B CG 1 ATOM 1311 C CD . LYS A 1 182 ? 24.591 70.300 -37.769 1.00 33.99 ? 238 LYS B CD 1 ATOM 1312 C CE . LYS A 1 182 ? 23.194 70.348 -38.391 1.00 41.49 ? 238 LYS B CE 1 ATOM 1313 N NZ . LYS A 1 182 ? 23.119 69.583 -39.677 1.00 49.27 ? 238 LYS B NZ 1 ATOM 1314 N N . ARG A 1 183 ? 28.939 72.953 -35.522 1.00 12.83 ? 239 ARG B N 1 ATOM 1315 C CA . ARG A 1 183 ? 29.776 73.680 -34.570 1.00 13.41 ? 239 ARG B CA 1 ATOM 1316 C C . ARG A 1 183 ? 30.491 74.903 -35.115 1.00 12.91 ? 239 ARG B C 1 ATOM 1317 O O . ARG A 1 183 ? 31.227 75.517 -34.354 1.00 10.77 ? 239 ARG B O 1 ATOM 1318 C CB . ARG A 1 183 ? 30.792 72.752 -33.890 1.00 17.27 ? 239 ARG B CB 1 ATOM 1319 C CG . ARG A 1 183 ? 30.165 71.487 -33.348 1.00 22.92 ? 239 ARG B CG 1 ATOM 1320 C CD . ARG A 1 183 ? 31.102 70.733 -32.448 1.00 43.60 ? 239 ARG B CD 1 ATOM 1321 N NE . ARG A 1 183 ? 30.452 70.464 -31.168 1.00 67.65 ? 239 ARG B NE 1 ATOM 1322 C CZ . ARG A 1 183 ? 30.927 69.646 -30.235 1.00 78.02 ? 239 ARG B CZ 1 ATOM 1323 N NH1 . ARG A 1 183 ? 32.070 69.000 -30.436 1.00 78.84 ? 239 ARG B NH1 1 ATOM 1324 N NH2 . ARG A 1 183 ? 30.253 69.474 -29.101 1.00 81.27 ? 239 ARG B NH2 1 ATOM 1325 N N . VAL A 1 184 ? 30.341 75.229 -36.410 1.00 7.24 ? 240 VAL B N 1 ATOM 1326 C CA . VAL A 1 184 ? 31.160 76.294 -37.016 1.00 7.32 ? 240 VAL B CA 1 ATOM 1327 C C . VAL A 1 184 ? 30.771 77.705 -36.556 1.00 6.73 ? 240 VAL B C 1 ATOM 1328 O O . VAL A 1 184 ? 29.604 78.039 -36.427 1.00 12.37 ? 240 VAL B O 1 ATOM 1329 C CB . VAL A 1 184 ? 31.223 76.196 -38.588 1.00 16.53 ? 240 VAL B CB 1 ATOM 1330 C CG1 . VAL A 1 184 ? 30.058 76.941 -39.252 1.00 6.77 ? 240 VAL B CG1 1 ATOM 1331 C CG2 . VAL A 1 184 ? 32.548 76.727 -39.114 1.00 7.94 ? 240 VAL B CG2 1 ATOM 1332 N N . GLN A 1 185 ? 31.763 78.543 -36.315 1.00 6.95 ? 241 GLN B N 1 ATOM 1333 C CA . GLN A 1 185 ? 31.530 79.827 -35.657 1.00 13.26 ? 241 GLN B CA 1 ATOM 1334 C C . GLN A 1 185 ? 31.825 81.000 -36.570 1.00 12.30 ? 241 GLN B C 1 ATOM 1335 O O . GLN A 1 185 ? 31.032 81.941 -36.680 1.00 7.64 ? 241 GLN B O 1 ATOM 1336 C CB . GLN A 1 185 ? 32.290 79.937 -34.334 1.00 6.78 ? 241 GLN B CB 1 ATOM 1337 C CG . GLN A 1 185 ? 31.642 79.190 -33.176 1.00 19.67 ? 241 GLN B CG 1 ATOM 1338 C CD . GLN A 1 185 ? 32.349 79.443 -31.834 1.00 23.81 ? 241 GLN B CD 1 ATOM 1339 O OE1 . GLN A 1 185 ? 32.853 78.513 -31.200 1.00 23.57 ? 241 GLN B OE1 1 ATOM 1340 N NE2 . GLN A 1 185 ? 32.378 80.706 -31.402 1.00 24.77 ? 241 GLN B NE2 1 ATOM 1341 N N . THR A 1 186 ? 33.038 80.998 -37.105 1.00 19.59 ? 242 THR B N 1 ATOM 1342 C CA . THR A 1 186 ? 33.403 81.900 -38.186 1.00 17.49 ? 242 THR B CA 1 ATOM 1343 C C . THR A 1 186 ? 33.571 81.204 -39.544 1.00 7.83 ? 242 THR B C 1 ATOM 1344 O O . THR A 1 186 ? 34.302 80.221 -39.675 1.00 8.61 ? 242 THR B O 1 ATOM 1345 C CB . THR A 1 186 ? 34.693 82.640 -37.857 1.00 18.76 ? 242 THR B CB 1 ATOM 1346 O OG1 . THR A 1 186 ? 34.470 83.469 -36.705 1.00 17.71 ? 242 THR B OG1 1 ATOM 1347 C CG2 . THR A 1 186 ? 35.117 83.494 -39.056 1.00 7.45 ? 242 THR B CG2 1 ATOM 1348 N N . ILE A 1 187 ? 32.882 81.728 -40.551 1.00 10.85 ? 243 ILE B N 1 ATOM 1349 C CA . ILE A 1 187 ? 33.173 81.381 -41.934 1.00 7.11 ? 243 ILE B CA 1 ATOM 1350 C C . ILE A 1 187 ? 33.741 82.597 -42.662 1.00 18.19 ? 243 ILE B C 1 ATOM 1351 O O . ILE A 1 187 ? 33.041 83.577 -42.865 1.00 6.55 ? 243 ILE B O 1 ATOM 1352 C CB . ILE A 1 187 ? 31.935 80.826 -42.645 1.00 15.72 ? 243 ILE B CB 1 ATOM 1353 C CG1 . ILE A 1 187 ? 31.606 79.456 -42.051 1.00 6.91 ? 243 ILE B CG1 1 ATOM 1354 C CG2 . ILE A 1 187 ? 32.174 80.713 -44.185 1.00 11.81 ? 243 ILE B CG2 1 ATOM 1355 C CD1 . ILE A 1 187 ? 30.330 78.859 -42.547 1.00 7.51 ? 243 ILE B CD1 1 ATOM 1356 N N . ALA A 1 188 ? 35.030 82.557 -43.001 1.00 16.83 ? 244 ALA B N 1 ATOM 1357 C CA . ALA A 1 188 ? 35.635 83.688 -43.690 1.00 10.56 ? 244 ALA B CA 1 ATOM 1358 C C . ALA A 1 188 ? 36.103 83.314 -45.090 1.00 11.03 ? 244 ALA B C 1 ATOM 1359 O O . ALA A 1 188 ? 37.179 82.736 -45.276 1.00 11.49 ? 244 ALA B O 1 ATOM 1360 C CB . ALA A 1 188 ? 36.798 84.212 -42.874 1.00 8.29 ? 244 ALA B CB 1 ATOM 1361 N N . ILE A 1 189 ? 35.315 83.665 -46.096 1.00 17.86 ? 245 ILE B N 1 ATOM 1362 C CA . ILE A 1 189 ? 35.797 83.521 -47.461 1.00 14.24 ? 245 ILE B CA 1 ATOM 1363 C C . ILE A 1 189 ? 35.454 84.806 -48.198 1.00 12.23 ? 245 ILE B C 1 ATOM 1364 O O . ILE A 1 189 ? 34.421 84.894 -48.848 1.00 14.38 ? 245 ILE B O 1 ATOM 1365 C CB . ILE A 1 189 ? 35.088 82.314 -48.137 1.00 9.72 ? 245 ILE B CB 1 ATOM 1366 C CG1 . ILE A 1 189 ? 35.180 81.081 -47.229 1.00 8.48 ? 245 ILE B CG1 1 ATOM 1367 C CG2 . ILE A 1 189 ? 35.690 82.012 -49.515 1.00 15.06 ? 245 ILE B CG2 1 ATOM 1368 C CD1 . ILE A 1 189 ? 34.342 79.878 -47.648 1.00 8.43 ? 245 ILE B CD1 1 ATOM 1369 N N . TYR A 1 190 ? 36.407 85.726 -48.252 1.00 12.45 ? 246 TYR B N 1 ATOM 1370 C CA . TYR A 1 190 ? 36.147 87.053 -48.788 1.00 10.55 ? 246 TYR B CA 1 ATOM 1371 C C . TYR A 1 190 ? 37.274 87.476 -49.725 1.00 13.45 ? 246 TYR B C 1 ATOM 1372 O O . TYR A 1 190 ? 38.413 87.010 -49.589 1.00 18.65 ? 246 TYR B O 1 ATOM 1373 C CB . TYR A 1 190 ? 35.950 88.075 -47.658 1.00 9.04 ? 246 TYR B CB 1 ATOM 1374 C CG . TYR A 1 190 ? 37.083 88.148 -46.652 1.00 11.77 ? 246 TYR B CG 1 ATOM 1375 C CD1 . TYR A 1 190 ? 38.258 88.809 -46.953 1.00 8.22 ? 246 TYR B CD1 1 ATOM 1376 C CD2 . TYR A 1 190 ? 36.959 87.576 -45.390 1.00 8.39 ? 246 TYR B CD2 1 ATOM 1377 C CE1 . TYR A 1 190 ? 39.280 88.879 -46.049 1.00 8.74 ? 246 TYR B CE1 1 ATOM 1378 C CE2 . TYR A 1 190 ? 37.985 87.652 -44.466 1.00 8.22 ? 246 TYR B CE2 1 ATOM 1379 C CZ . TYR A 1 190 ? 39.141 88.300 -44.803 1.00 9.70 ? 246 TYR B CZ 1 ATOM 1380 O OH . TYR A 1 190 ? 40.184 88.376 -43.907 1.00 9.97 ? 246 TYR B OH 1 ATOM 1381 N N . THR A 1 191 ? 36.947 88.362 -50.662 1.00 14.61 ? 247 THR B N 1 ATOM 1382 C CA . THR A 1 191 ? 37.878 88.741 -51.718 1.00 21.64 ? 247 THR B CA 1 ATOM 1383 C C . THR A 1 191 ? 38.322 87.484 -52.457 1.00 8.86 ? 247 THR B C 1 ATOM 1384 O O . THR A 1 191 ? 39.495 87.163 -52.540 1.00 9.57 ? 247 THR B O 1 ATOM 1385 C CB . THR A 1 191 ? 39.068 89.513 -51.146 1.00 26.75 ? 247 THR B CB 1 ATOM 1386 O OG1 . THR A 1 191 ? 38.597 90.393 -50.109 1.00 8.23 ? 247 THR B OG1 1 ATOM 1387 C CG2 . THR A 1 191 ? 39.783 90.293 -52.258 1.00 9.02 ? 247 THR B CG2 1 ATOM 1388 N N . SER A 1 192 ? 37.331 86.748 -52.931 1.00 11.74 ? 248 SER B N 1 ATOM 1389 C CA . SER A 1 192 ? 37.545 85.524 -53.692 1.00 19.69 ? 248 SER B CA 1 ATOM 1390 C C . SER A 1 192 ? 36.764 85.518 -55.005 1.00 21.55 ? 248 SER B C 1 ATOM 1391 O O . SER A 1 192 ? 36.391 86.572 -55.519 1.00 18.48 ? 248 SER B O 1 ATOM 1392 C CB . SER A 1 192 ? 37.245 84.283 -52.860 1.00 17.53 ? 248 SER B CB 1 ATOM 1393 O OG . SER A 1 192 ? 38.262 84.094 -51.901 1.00 12.59 ? 248 SER B OG 1 ATOM 1394 N N . LEU A 1 193 ? 36.667 84.340 -55.607 1.00 19.33 ? 249 LEU B N 1 ATOM 1395 C CA . LEU A 1 193 ? 35.899 84.125 -56.840 1.00 19.12 ? 249 LEU B CA 1 ATOM 1396 C C . LEU A 1 193 ? 34.498 83.511 -56.686 1.00 13.72 ? 249 LEU B C 1 ATOM 1397 O O . LEU A 1 193 ? 33.937 83.033 -57.664 1.00 20.26 ? 249 LEU B O 1 ATOM 1398 C CB . LEU A 1 193 ? 36.735 83.385 -57.898 1.00 9.57 ? 249 LEU B CB 1 ATOM 1399 C CG . LEU A 1 193 ? 38.048 84.123 -58.198 1.00 36.17 ? 249 LEU B CG 1 ATOM 1400 C CD1 . LEU A 1 193 ? 38.947 83.375 -59.190 1.00 10.83 ? 249 LEU B CD1 1 ATOM 1401 C CD2 . LEU A 1 193 ? 37.737 85.518 -58.692 1.00 9.60 ? 249 LEU B CD2 1 ATOM 1402 N N . LEU A 1 194 ? 33.983 83.408 -55.467 1.00 15.12 ? 250 LEU B N 1 ATOM 1403 C CA . LEU A 1 194 ? 32.654 82.804 -55.247 1.00 11.83 ? 250 LEU B CA 1 ATOM 1404 C C . LEU A 1 194 ? 31.528 83.395 -56.102 1.00 12.47 ? 250 LEU B C 1 ATOM 1405 O O . LEU A 1 194 ? 31.403 84.616 -56.223 1.00 13.47 ? 250 LEU B O 1 ATOM 1406 C CB . LEU A 1 194 ? 32.245 82.933 -53.781 1.00 11.44 ? 250 LEU B CB 1 ATOM 1407 C CG . LEU A 1 194 ? 32.898 82.057 -52.717 1.00 20.73 ? 250 LEU B CG 1 ATOM 1408 C CD1 . LEU A 1 194 ? 32.146 82.257 -51.371 1.00 8.45 ? 250 LEU B CD1 1 ATOM 1409 C CD2 . LEU A 1 194 ? 32.936 80.578 -53.133 1.00 8.09 ? 250 LEU B CD2 1 ATOM 1410 N N . SER A 1 195 ? 30.704 82.526 -56.680 1.00 9.72 ? 251 SER B N 1 ATOM 1411 C CA . SER A 1 195 ? 29.515 82.954 -57.424 1.00 17.11 ? 251 SER B CA 1 ATOM 1412 C C . SER A 1 195 ? 28.350 82.013 -57.157 1.00 18.80 ? 251 SER B C 1 ATOM 1413 O O . SER A 1 195 ? 28.490 81.030 -56.444 1.00 28.88 ? 251 SER B O 1 ATOM 1414 C CB . SER A 1 195 ? 29.799 83.022 -58.928 1.00 20.01 ? 251 SER B CB 1 ATOM 1415 O OG . SER A 1 195 ? 30.468 81.853 -59.361 1.00 26.12 ? 251 SER B OG 1 ATOM 1416 N N . GLY A 1 196 ? 27.193 82.307 -57.731 1.00 19.62 ? 252 GLY B N 1 ATOM 1417 C CA . GLY A 1 196 ? 26.003 81.541 -57.404 1.00 21.67 ? 252 GLY B CA 1 ATOM 1418 C C . GLY A 1 196 ? 25.464 81.930 -56.037 1.00 19.87 ? 252 GLY B C 1 ATOM 1419 O O . GLY A 1 196 ? 26.032 82.779 -55.348 1.00 13.43 ? 252 GLY B O 1 ATOM 1420 N N . PRO A 1 197 ? 24.338 81.336 -55.651 1.00 19.23 ? 253 PRO B N 1 ATOM 1421 C CA . PRO A 1 197 ? 23.675 81.696 -54.393 1.00 14.97 ? 253 PRO B CA 1 ATOM 1422 C C . PRO A 1 197 ? 24.273 81.097 -53.102 1.00 18.25 ? 253 PRO B C 1 ATOM 1423 O O . PRO A 1 197 ? 24.891 80.031 -53.118 1.00 22.41 ? 253 PRO B O 1 ATOM 1424 C CB . PRO A 1 197 ? 22.231 81.216 -54.610 1.00 14.31 ? 253 PRO B CB 1 ATOM 1425 C CG . PRO A 1 197 ? 22.344 80.108 -55.617 1.00 18.16 ? 253 PRO B CG 1 ATOM 1426 C CD . PRO A 1 197 ? 23.499 80.484 -56.515 1.00 22.13 ? 253 PRO B CD 1 ATOM 1427 N N . ILE A 1 198 ? 24.089 81.820 -51.995 1.00 16.20 ? 254 ILE B N 1 ATOM 1428 C CA . ILE A 1 198 ? 24.346 81.314 -50.653 1.00 10.87 ? 254 ILE B CA 1 ATOM 1429 C C . ILE A 1 198 ? 23.351 80.195 -50.412 1.00 12.81 ? 254 ILE B C 1 ATOM 1430 O O . ILE A 1 198 ? 22.152 80.392 -50.599 1.00 17.08 ? 254 ILE B O 1 ATOM 1431 C CB . ILE A 1 198 ? 24.098 82.414 -49.599 1.00 14.70 ? 254 ILE B CB 1 ATOM 1432 C CG1 . ILE A 1 198 ? 25.037 83.598 -49.818 1.00 9.20 ? 254 ILE B CG1 1 ATOM 1433 C CG2 . ILE A 1 198 ? 24.268 81.873 -48.165 1.00 19.25 ? 254 ILE B CG2 1 ATOM 1434 C CD1 . ILE A 1 198 ? 24.569 84.856 -49.113 1.00 5.52 ? 254 ILE B CD1 1 ATOM 1435 N N . PRO A 1 199 ? 23.831 79.004 -50.020 1.00 13.15 ? 255 PRO B N 1 ATOM 1436 C CA . PRO A 1 199 ? 22.829 77.938 -49.882 1.00 9.70 ? 255 PRO B CA 1 ATOM 1437 C C . PRO A 1 199 ? 21.950 78.174 -48.664 1.00 12.34 ? 255 PRO B C 1 ATOM 1438 O O . PRO A 1 199 ? 22.470 78.584 -47.620 1.00 15.16 ? 255 PRO B O 1 ATOM 1439 C CB . PRO A 1 199 ? 23.671 76.673 -49.709 1.00 8.35 ? 255 PRO B CB 1 ATOM 1440 C CG . PRO A 1 199 ? 24.996 77.162 -49.180 1.00 11.33 ? 255 PRO B CG 1 ATOM 1441 C CD . PRO A 1 199 ? 25.204 78.541 -49.756 1.00 10.09 ? 255 PRO B CD 1 ATOM 1442 N N . ASP A 1 200 ? 20.647 77.934 -48.810 1.00 4.25 ? 256 ASP B N 1 ATOM 1443 C CA . ASP A 1 200 ? 19.709 77.991 -47.700 1.00 10.69 ? 256 ASP B CA 1 ATOM 1444 C C . ASP A 1 200 ? 20.169 77.129 -46.518 1.00 15.33 ? 256 ASP B C 1 ATOM 1445 O O . ASP A 1 200 ? 19.982 77.512 -45.345 1.00 14.32 ? 256 ASP B O 1 ATOM 1446 C CB . ASP A 1 200 ? 18.297 77.601 -48.146 1.00 11.71 ? 256 ASP B CB 1 ATOM 1447 C CG . ASP A 1 200 ? 17.635 78.682 -48.983 1.00 31.02 ? 256 ASP B CG 1 ATOM 1448 O OD1 . ASP A 1 200 ? 16.976 79.572 -48.398 1.00 36.47 ? 256 ASP B OD1 1 ATOM 1449 O OD2 . ASP A 1 200 ? 17.778 78.646 -50.227 1.00 41.13 ? 256 ASP B OD2 1 ATOM 1450 N N . GLU A 1 201 ? 20.827 76.009 -46.819 1.00 9.60 ? 257 GLU B N 1 ATOM 1451 C CA . GLU A 1 201 ? 21.290 75.100 -45.771 1.00 14.08 ? 257 GLU B CA 1 ATOM 1452 C C . GLU A 1 201 ? 22.174 75.772 -44.736 1.00 11.71 ? 257 GLU B C 1 ATOM 1453 O O . GLU A 1 201 ? 22.368 75.239 -43.656 1.00 18.85 ? 257 GLU B O 1 ATOM 1454 C CB . GLU A 1 201 ? 21.983 73.869 -46.346 1.00 16.80 ? 257 GLU B CB 1 ATOM 1455 C CG . GLU A 1 201 ? 21.040 72.958 -47.097 1.00 15.64 ? 257 GLU B CG 1 ATOM 1456 C CD . GLU A 1 201 ? 20.809 73.415 -48.539 1.00 21.77 ? 257 GLU B CD 1 ATOM 1457 O OE1 . GLU A 1 201 ? 21.320 74.498 -48.933 1.00 14.38 ? 257 GLU B OE1 1 ATOM 1458 O OE2 . GLU A 1 201 ? 20.127 72.672 -49.286 1.00 28.87 ? 257 GLU B OE2 1 ATOM 1459 N N . ILE A 1 202 ? 22.696 76.947 -45.055 1.00 6.92 ? 258 ILE B N 1 ATOM 1460 C CA . ILE A 1 202 ? 23.528 77.658 -44.098 1.00 9.58 ? 258 ILE B CA 1 ATOM 1461 C C . ILE A 1 202 ? 22.776 77.974 -42.804 1.00 8.06 ? 258 ILE B C 1 ATOM 1462 O O . ILE A 1 202 ? 23.389 78.148 -41.764 1.00 12.02 ? 258 ILE B O 1 ATOM 1463 C CB . ILE A 1 202 ? 24.137 78.960 -44.694 1.00 22.77 ? 258 ILE B CB 1 ATOM 1464 C CG1 . ILE A 1 202 ? 25.625 79.049 -44.340 1.00 20.41 ? 258 ILE B CG1 1 ATOM 1465 C CG2 . ILE A 1 202 ? 23.384 80.196 -44.212 1.00 21.17 ? 258 ILE B CG2 1 ATOM 1466 C CD1 . ILE A 1 202 ? 26.146 80.440 -44.238 1.00 13.60 ? 258 ILE B CD1 1 ATOM 1467 N N . GLY A 1 203 ? 21.450 78.032 -42.866 1.00 7.34 ? 259 GLY B N 1 ATOM 1468 C CA . GLY A 1 203 ? 20.657 78.296 -41.678 1.00 15.69 ? 259 GLY B CA 1 ATOM 1469 C C . GLY A 1 203 ? 20.732 77.149 -40.670 1.00 20.59 ? 259 GLY B C 1 ATOM 1470 O O . GLY A 1 203 ? 20.359 77.306 -39.502 1.00 11.97 ? 259 GLY B O 1 ATOM 1471 N N . TYR A 1 204 ? 21.219 75.995 -41.126 1.00 20.29 ? 260 TYR B N 1 ATOM 1472 C CA . TYR A 1 204 ? 21.476 74.855 -40.248 1.00 14.88 ? 260 TYR B CA 1 ATOM 1473 C C . TYR A 1 204 ? 22.745 75.007 -39.406 1.00 15.96 ? 260 TYR B C 1 ATOM 1474 O O . TYR A 1 204 ? 23.006 74.155 -38.558 1.00 22.17 ? 260 TYR B O 1 ATOM 1475 C CB . TYR A 1 204 ? 21.571 73.539 -41.031 1.00 7.63 ? 260 TYR B CB 1 ATOM 1476 C CG . TYR A 1 204 ? 20.272 73.047 -41.608 1.00 4.87 ? 260 TYR B CG 1 ATOM 1477 C CD1 . TYR A 1 204 ? 19.104 73.027 -40.852 1.00 4.56 ? 260 TYR B CD1 1 ATOM 1478 C CD2 . TYR A 1 204 ? 20.208 72.617 -42.930 1.00 9.15 ? 260 TYR B CD2 1 ATOM 1479 C CE1 . TYR A 1 204 ? 17.903 72.574 -41.401 1.00 5.09 ? 260 TYR B CE1 1 ATOM 1480 C CE2 . TYR A 1 204 ? 19.033 72.157 -43.477 1.00 5.00 ? 260 TYR B CE2 1 ATOM 1481 C CZ . TYR A 1 204 ? 17.881 72.136 -42.721 1.00 12.93 ? 260 TYR B CZ 1 ATOM 1482 O OH . TYR A 1 204 ? 16.713 71.678 -43.311 1.00 12.91 ? 260 TYR B OH 1 ATOM 1483 N N . CYS A 1 205 ? 23.532 76.068 -39.604 1.00 9.01 ? 261 CYS B N 1 ATOM 1484 C CA . CYS A 1 205 ? 24.754 76.157 -38.815 1.00 10.24 ? 261 CYS B CA 1 ATOM 1485 C C . CYS A 1 205 ? 24.433 76.910 -37.548 1.00 19.56 ? 261 CYS B C 1 ATOM 1486 O O . CYS A 1 205 ? 24.592 78.132 -37.474 1.00 21.60 ? 261 CYS B O 1 ATOM 1487 C CB . CYS A 1 205 ? 25.800 76.940 -39.604 1.00 5.17 ? 261 CYS B CB 1 ATOM 1488 S SG . CYS A 1 205 ? 26.209 76.160 -41.175 1.00 13.37 ? 261 CYS B SG 1 ATOM 1489 N N . THR A 1 206 ? 24.162 76.152 -36.495 1.00 22.49 ? 262 THR B N 1 ATOM 1490 C CA . THR A 1 206 ? 23.412 76.696 -35.366 1.00 18.37 ? 262 THR B CA 1 ATOM 1491 C C . THR A 1 206 ? 24.288 77.586 -34.507 1.00 14.21 ? 262 THR B C 1 ATOM 1492 O O . THR A 1 206 ? 23.796 78.483 -33.840 1.00 19.87 ? 262 THR B O 1 ATOM 1493 C CB . THR A 1 206 ? 22.727 75.571 -34.524 1.00 25.28 ? 262 THR B CB 1 ATOM 1494 O OG1 . THR A 1 206 ? 23.142 75.654 -33.158 1.00 31.11 ? 262 THR B OG1 1 ATOM 1495 C CG2 . THR A 1 206 ? 23.096 74.212 -35.045 1.00 22.00 ? 262 THR B CG2 1 ATOM 1496 N N . GLU A 1 207 ? 25.591 77.341 -34.559 1.00 4.71 ? 263 GLU B N 1 ATOM 1497 C CA . GLU A 1 207 ? 26.572 78.111 -33.810 1.00 4.81 ? 263 GLU B CA 1 ATOM 1498 C C . GLU A 1 207 ? 27.229 79.259 -34.572 1.00 4.77 ? 263 GLU B C 1 ATOM 1499 O O . GLU A 1 207 ? 28.096 79.902 -34.026 1.00 7.52 ? 263 GLU B O 1 ATOM 1500 C CB . GLU A 1 207 ? 27.683 77.172 -33.317 1.00 8.93 ? 263 GLU B CB 1 ATOM 1501 C CG . GLU A 1 207 ? 27.169 76.053 -32.450 1.00 10.81 ? 263 GLU B CG 1 ATOM 1502 C CD . GLU A 1 207 ? 26.630 76.581 -31.133 1.00 24.82 ? 263 GLU B CD 1 ATOM 1503 O OE1 . GLU A 1 207 ? 27.310 77.440 -30.520 1.00 27.13 ? 263 GLU B OE1 1 ATOM 1504 O OE2 . GLU A 1 207 ? 25.526 76.153 -30.719 1.00 29.10 ? 263 GLU B OE2 1 ATOM 1505 N N . LEU A 1 208 ? 26.854 79.495 -35.831 1.00 17.35 ? 264 LEU B N 1 ATOM 1506 C CA . LEU A 1 208 ? 27.464 80.564 -36.634 1.00 4.61 ? 264 LEU B CA 1 ATOM 1507 C C . LEU A 1 208 ? 27.364 81.964 -36.006 1.00 14.60 ? 264 LEU B C 1 ATOM 1508 O O . LEU A 1 208 ? 26.300 82.390 -35.564 1.00 5.36 ? 264 LEU B O 1 ATOM 1509 C CB . LEU A 1 208 ? 26.862 80.599 -38.035 1.00 9.72 ? 264 LEU B CB 1 ATOM 1510 C CG . LEU A 1 208 ? 27.669 81.407 -39.046 1.00 6.02 ? 264 LEU B CG 1 ATOM 1511 C CD1 . LEU A 1 208 ? 29.022 80.753 -39.199 1.00 5.30 ? 264 LEU B CD1 1 ATOM 1512 C CD2 . LEU A 1 208 ? 26.950 81.464 -40.389 1.00 6.68 ? 264 LEU B CD2 1 ATOM 1513 N N . GLN A 1 209 ? 28.487 82.672 -35.993 1.00 4.44 ? 265 GLN B N 1 ATOM 1514 C CA . GLN A 1 209 ? 28.625 83.951 -35.304 1.00 8.58 ? 265 GLN B CA 1 ATOM 1515 C C . GLN A 1 209 ? 29.028 85.008 -36.304 1.00 5.22 ? 265 GLN B C 1 ATOM 1516 O O . GLN A 1 209 ? 28.459 86.095 -36.339 1.00 8.50 ? 265 GLN B O 1 ATOM 1517 C CB . GLN A 1 209 ? 29.638 83.894 -34.135 1.00 5.30 ? 265 GLN B CB 1 ATOM 1518 C CG . GLN A 1 209 ? 29.206 83.024 -32.967 1.00 21.09 ? 265 GLN B CG 1 ATOM 1519 C CD . GLN A 1 209 ? 30.082 83.183 -31.719 1.00 31.43 ? 265 GLN B CD 1 ATOM 1520 O OE1 . GLN A 1 209 ? 30.951 84.064 -31.641 1.00 28.08 ? 265 GLN B OE1 1 ATOM 1521 N NE2 . GLN A 1 209 ? 29.850 82.317 -30.735 1.00 35.17 ? 265 GLN B NE2 1 ATOM 1522 N N . ASN A 1 210 ? 30.116 84.718 -37.009 1.00 4.68 ? 266 ASN B N 1 ATOM 1523 C CA . ASN A 1 210 ? 30.647 85.591 -38.040 1.00 4.75 ? 266 ASN B CA 1 ATOM 1524 C C . ASN A 1 210 ? 30.615 84.959 -39.427 1.00 9.14 ? 266 ASN B C 1 ATOM 1525 O O . ASN A 1 210 ? 31.203 83.891 -39.655 1.00 9.65 ? 266 ASN B O 1 ATOM 1526 C CB . ASN A 1 210 ? 32.076 85.966 -37.676 1.00 7.06 ? 266 ASN B CB 1 ATOM 1527 C CG . ASN A 1 210 ? 32.217 86.311 -36.215 1.00 6.92 ? 266 ASN B CG 1 ATOM 1528 O OD1 . ASN A 1 210 ? 31.466 87.123 -35.684 1.00 8.80 ? 266 ASN B OD1 1 ATOM 1529 N ND2 . ASN A 1 210 ? 33.145 85.652 -35.543 1.00 10.57 ? 266 ASN B ND2 1 ATOM 1530 N N . LEU A 1 211 ? 29.914 85.609 -40.353 1.00 7.69 ? 267 LEU B N 1 ATOM 1531 C CA . LEU A 1 211 ? 29.862 85.127 -41.738 1.00 4.71 ? 267 LEU B CA 1 ATOM 1532 C C . LEU A 1 211 ? 30.386 86.213 -42.653 1.00 17.92 ? 267 LEU B C 1 ATOM 1533 O O . LEU A 1 211 ? 29.747 87.268 -42.784 1.00 4.25 ? 267 LEU B O 1 ATOM 1534 C CB . LEU A 1 211 ? 28.431 84.754 -42.130 1.00 4.26 ? 267 LEU B CB 1 ATOM 1535 C CG . LEU A 1 211 ? 28.254 84.335 -43.592 1.00 12.83 ? 267 LEU B CG 1 ATOM 1536 C CD1 . LEU A 1 211 ? 29.117 83.121 -43.924 1.00 5.05 ? 267 LEU B CD1 1 ATOM 1537 C CD2 . LEU A 1 211 ? 26.789 84.061 -43.909 1.00 9.82 ? 267 LEU B CD2 1 ATOM 1538 N N . TYR A 1 212 ? 31.563 85.981 -43.244 1.00 5.33 ? 268 TYR B N 1 ATOM 1539 C CA . TYR A 1 212 ? 32.178 86.959 -44.133 1.00 11.24 ? 268 TYR B CA 1 ATOM 1540 C C . TYR A 1 212 ? 32.332 86.430 -45.544 1.00 15.39 ? 268 TYR B C 1 ATOM 1541 O O . TYR A 1 212 ? 33.235 85.649 -45.828 1.00 15.61 ? 268 TYR B O 1 ATOM 1542 C CB . TYR A 1 212 ? 33.567 87.332 -43.609 1.00 11.99 ? 268 TYR B CB 1 ATOM 1543 C CG . TYR A 1 212 ? 33.578 87.766 -42.155 1.00 11.52 ? 268 TYR B CG 1 ATOM 1544 C CD1 . TYR A 1 212 ? 32.514 88.467 -41.618 1.00 11.49 ? 268 TYR B CD1 1 ATOM 1545 C CD2 . TYR A 1 212 ? 34.659 87.467 -41.320 1.00 12.53 ? 268 TYR B CD2 1 ATOM 1546 C CE1 . TYR A 1 212 ? 32.514 88.854 -40.287 1.00 17.97 ? 268 TYR B CE1 1 ATOM 1547 C CE2 . TYR A 1 212 ? 34.669 87.865 -39.983 1.00 13.14 ? 268 TYR B CE2 1 ATOM 1548 C CZ . TYR A 1 212 ? 33.590 88.559 -39.481 1.00 17.59 ? 268 TYR B CZ 1 ATOM 1549 O OH . TYR A 1 212 ? 33.567 88.955 -38.162 1.00 23.36 ? 268 TYR B OH 1 ATOM 1550 N N . LEU A 1 213 ? 31.428 86.858 -46.414 1.00 15.82 ? 269 LEU B N 1 ATOM 1551 C CA . LEU A 1 213 ? 31.431 86.544 -47.844 1.00 10.11 ? 269 LEU B CA 1 ATOM 1552 C C . LEU A 1 213 ? 31.722 87.710 -48.830 1.00 17.39 ? 269 LEU B C 1 ATOM 1553 O O . LEU A 1 213 ? 31.411 87.619 -50.025 1.00 10.98 ? 269 LEU B O 1 ATOM 1554 C CB . LEU A 1 213 ? 30.195 85.705 -48.203 1.00 14.21 ? 269 LEU B CB 1 ATOM 1555 C CG . LEU A 1 213 ? 30.123 84.403 -47.374 1.00 12.38 ? 269 LEU B CG 1 ATOM 1556 C CD1 . LEU A 1 213 ? 28.832 83.670 -47.557 1.00 5.10 ? 269 LEU B CD1 1 ATOM 1557 C CD2 . LEU A 1 213 ? 31.285 83.459 -47.695 1.00 6.13 ? 269 LEU B CD2 1 ATOM 1558 N N . TYR A 1 214 ? 32.180 88.848 -48.320 1.00 17.25 ? 270 TYR B N 1 ATOM 1559 C CA . TYR A 1 214 ? 32.279 90.055 -49.152 1.00 14.78 ? 270 TYR B CA 1 ATOM 1560 C C . TYR A 1 214 ? 33.278 89.991 -50.345 1.00 14.58 ? 270 TYR B C 1 ATOM 1561 O O . TYR A 1 214 ? 34.184 89.161 -50.374 1.00 11.21 ? 270 TYR B O 1 ATOM 1562 C CB . TYR A 1 214 ? 32.505 91.295 -48.270 1.00 7.18 ? 270 TYR B CB 1 ATOM 1563 C CG . TYR A 1 214 ? 33.802 91.321 -47.469 1.00 7.45 ? 270 TYR B CG 1 ATOM 1564 C CD1 . TYR A 1 214 ? 34.958 91.861 -48.006 1.00 5.95 ? 270 TYR B CD1 1 ATOM 1565 C CD2 . TYR A 1 214 ? 33.851 90.861 -46.152 1.00 13.89 ? 270 TYR B CD2 1 ATOM 1566 C CE1 . TYR A 1 214 ? 36.138 91.925 -47.278 1.00 6.49 ? 270 TYR B CE1 1 ATOM 1567 C CE2 . TYR A 1 214 ? 35.036 90.908 -45.412 1.00 7.10 ? 270 TYR B CE2 1 ATOM 1568 C CZ . TYR A 1 214 ? 36.178 91.442 -45.988 1.00 9.85 ? 270 TYR B CZ 1 ATOM 1569 O OH . TYR A 1 214 ? 37.366 91.513 -45.278 1.00 9.85 ? 270 TYR B OH 1 ATOM 1570 N N . GLN A 1 215 ? 33.086 90.852 -51.340 1.00 14.31 ? 271 GLN B N 1 ATOM 1571 C CA . GLN A 1 215 ? 33.954 90.870 -52.544 1.00 13.08 ? 271 GLN B CA 1 ATOM 1572 C C . GLN A 1 215 ? 34.056 89.533 -53.283 1.00 9.25 ? 271 GLN B C 1 ATOM 1573 O O . GLN A 1 215 ? 35.143 88.987 -53.476 1.00 9.34 ? 271 GLN B O 1 ATOM 1574 C CB . GLN A 1 215 ? 35.342 91.435 -52.245 1.00 10.60 ? 271 GLN B CB 1 ATOM 1575 C CG . GLN A 1 215 ? 35.269 92.775 -51.520 1.00 19.48 ? 271 GLN B CG 1 ATOM 1576 C CD . GLN A 1 215 ? 36.610 93.452 -51.387 1.00 17.61 ? 271 GLN B CD 1 ATOM 1577 O OE1 . GLN A 1 215 ? 37.508 92.967 -50.697 1.00 21.08 ? 271 GLN B OE1 1 ATOM 1578 N NE2 . GLN A 1 215 ? 36.756 94.583 -52.055 1.00 14.95 ? 271 GLN B NE2 1 ATOM 1579 N N . ASN A 1 216 ? 32.899 89.011 -53.661 1.00 6.03 ? 272 ASN B N 1 ATOM 1580 C CA . ASN A 1 216 ? 32.784 87.857 -54.537 1.00 12.27 ? 272 ASN B CA 1 ATOM 1581 C C . ASN A 1 216 ? 31.779 88.224 -55.649 1.00 9.62 ? 272 ASN B C 1 ATOM 1582 O O . ASN A 1 216 ? 31.452 89.397 -55.842 1.00 5.57 ? 272 ASN B O 1 ATOM 1583 C CB . ASN A 1 216 ? 32.318 86.610 -53.761 1.00 13.96 ? 272 ASN B CB 1 ATOM 1584 C CG . ASN A 1 216 ? 33.383 86.069 -52.811 1.00 18.15 ? 272 ASN B CG 1 ATOM 1585 O OD1 . ASN A 1 216 ? 34.350 85.434 -53.243 1.00 7.47 ? 272 ASN B OD1 1 ATOM 1586 N ND2 . ASN A 1 216 ? 33.204 86.311 -51.506 1.00 7.57 ? 272 ASN B ND2 1 ATOM 1587 N N . SER A 1 217 ? 31.372 87.241 -56.431 1.00 6.10 ? 273 SER B N 1 ATOM 1588 C CA . SER A 1 217 ? 30.253 87.384 -57.368 1.00 12.28 ? 273 SER B CA 1 ATOM 1589 C C . SER A 1 217 ? 28.916 86.786 -56.936 1.00 11.73 ? 273 SER B C 1 ATOM 1590 O O . SER A 1 217 ? 28.087 86.479 -57.780 1.00 29.66 ? 273 SER B O 1 ATOM 1591 C CB . SER A 1 217 ? 30.631 86.996 -58.795 1.00 10.82 ? 273 SER B CB 1 ATOM 1592 O OG . SER A 1 217 ? 31.747 87.774 -59.187 1.00 15.12 ? 273 SER B OG 1 ATOM 1593 N N . ILE A 1 218 ? 28.769 86.496 -55.653 1.00 10.02 ? 274 ILE B N 1 ATOM 1594 C CA . ILE A 1 218 ? 27.578 85.822 -55.126 1.00 8.57 ? 274 ILE B CA 1 ATOM 1595 C C . ILE A 1 218 ? 26.266 86.446 -55.610 1.00 12.51 ? 274 ILE B C 1 ATOM 1596 O O . ILE A 1 218 ? 26.083 87.671 -55.588 1.00 5.98 ? 274 ILE B O 1 ATOM 1597 C CB . ILE A 1 218 ? 27.606 85.786 -53.576 1.00 4.75 ? 274 ILE B CB 1 ATOM 1598 C CG1 . ILE A 1 218 ? 28.804 84.955 -53.077 1.00 7.66 ? 274 ILE B CG1 1 ATOM 1599 C CG2 . ILE A 1 218 ? 26.315 85.223 -53.031 1.00 4.41 ? 274 ILE B CG2 1 ATOM 1600 C CD1 . ILE A 1 218 ? 29.105 85.154 -51.589 1.00 14.14 ? 274 ILE B CD1 1 ATOM 1601 N N . SER A 1 219 ? 25.375 85.579 -56.084 1.00 17.71 ? 275 SER B N 1 ATOM 1602 C CA . SER A 1 219 ? 24.135 86.003 -56.724 1.00 9.79 ? 275 SER B CA 1 ATOM 1603 C C . SER A 1 219 ? 22.945 85.435 -55.974 1.00 14.89 ? 275 SER B C 1 ATOM 1604 O O . SER A 1 219 ? 23.105 84.782 -54.949 1.00 28.28 ? 275 SER B O 1 ATOM 1605 C CB . SER A 1 219 ? 24.103 85.511 -58.161 1.00 11.50 ? 275 SER B CB 1 ATOM 1606 O OG . SER A 1 219 ? 24.271 84.101 -58.194 1.00 18.64 ? 275 SER B OG 1 ATOM 1607 N N . GLY A 1 220 ? 21.744 85.673 -56.481 1.00 7.27 ? 276 GLY B N 1 ATOM 1608 C CA . GLY A 1 220 ? 20.560 85.240 -55.770 1.00 4.65 ? 276 GLY B CA 1 ATOM 1609 C C . GLY A 1 220 ? 20.228 86.200 -54.642 1.00 16.57 ? 276 GLY B C 1 ATOM 1610 O O . GLY A 1 220 ? 20.725 87.330 -54.605 1.00 23.12 ? 276 GLY B O 1 ATOM 1611 N N . SER A 1 221 ? 19.374 85.749 -53.732 1.00 4.79 ? 277 SER B N 1 ATOM 1612 C CA . SER A 1 221 ? 18.931 86.553 -52.609 1.00 10.30 ? 277 SER B CA 1 ATOM 1613 C C . SER A 1 221 ? 19.468 86.017 -51.275 1.00 8.82 ? 277 SER B C 1 ATOM 1614 O O . SER A 1 221 ? 19.786 84.834 -51.156 1.00 10.51 ? 277 SER B O 1 ATOM 1615 C CB . SER A 1 221 ? 17.406 86.627 -52.586 1.00 14.47 ? 277 SER B CB 1 ATOM 1616 O OG . SER A 1 221 ? 16.837 85.352 -52.404 1.00 21.15 ? 277 SER B OG 1 ATOM 1617 N N . ILE A 1 222 ? 19.613 86.903 -50.294 1.00 12.22 ? 278 ILE B N 1 ATOM 1618 C CA . ILE A 1 222 ? 20.014 86.497 -48.947 1.00 10.99 ? 278 ILE B CA 1 ATOM 1619 C C . ILE A 1 222 ? 18.973 85.538 -48.417 1.00 7.01 ? 278 ILE B C 1 ATOM 1620 O O . ILE A 1 222 ? 17.807 85.904 -48.300 1.00 9.83 ? 278 ILE B O 1 ATOM 1621 C CB . ILE A 1 222 ? 20.062 87.706 -48.000 1.00 5.44 ? 278 ILE B CB 1 ATOM 1622 C CG1 . ILE A 1 222 ? 21.095 88.715 -48.495 1.00 5.07 ? 278 ILE B CG1 1 ATOM 1623 C CG2 . ILE A 1 222 ? 20.398 87.258 -46.589 1.00 2.16 ? 278 ILE B CG2 1 ATOM 1624 C CD1 . ILE A 1 222 ? 20.852 90.103 -48.033 1.00 6.85 ? 278 ILE B CD1 1 ATOM 1625 N N . PRO A 1 223 ? 19.374 84.303 -48.110 1.00 5.22 ? 279 PRO B N 1 ATOM 1626 C CA . PRO A 1 223 ? 18.370 83.320 -47.696 1.00 2.76 ? 279 PRO B CA 1 ATOM 1627 C C . PRO A 1 223 ? 17.680 83.705 -46.405 1.00 5.18 ? 279 PRO B C 1 ATOM 1628 O O . PRO A 1 223 ? 18.295 84.244 -45.492 1.00 19.06 ? 279 PRO B O 1 ATOM 1629 C CB . PRO A 1 223 ? 19.181 82.033 -47.522 1.00 3.05 ? 279 PRO B CB 1 ATOM 1630 C CG . PRO A 1 223 ? 20.581 82.501 -47.368 1.00 7.16 ? 279 PRO B CG 1 ATOM 1631 C CD . PRO A 1 223 ? 20.706 83.701 -48.234 1.00 6.32 ? 279 PRO B CD 1 ATOM 1632 N N . THR A 1 224 ? 16.385 83.442 -46.357 1.00 6.97 ? 280 THR B N 1 ATOM 1633 C CA . THR A 1 224 ? 15.554 83.719 -45.198 1.00 9.53 ? 280 THR B CA 1 ATOM 1634 C C . THR A 1 224 ? 16.046 82.946 -43.964 1.00 14.75 ? 280 THR B C 1 ATOM 1635 O O . THR A 1 224 ? 16.001 83.451 -42.839 1.00 14.83 ? 280 THR B O 1 ATOM 1636 C CB . THR A 1 224 ? 14.107 83.310 -45.502 1.00 5.75 ? 280 THR B CB 1 ATOM 1637 O OG1 . THR A 1 224 ? 13.547 84.228 -46.449 1.00 18.38 ? 280 THR B OG1 1 ATOM 1638 C CG2 . THR A 1 224 ? 13.292 83.369 -44.260 1.00 9.20 ? 280 THR B CG2 1 ATOM 1639 N N . THR A 1 225 ? 16.545 81.736 -44.204 1.00 2.66 ? 281 THR B N 1 ATOM 1640 C CA . THR A 1 225 ? 16.979 80.813 -43.167 1.00 2.76 ? 281 THR B CA 1 ATOM 1641 C C . THR A 1 225 ? 18.012 81.417 -42.230 1.00 12.06 ? 281 THR B C 1 ATOM 1642 O O . THR A 1 225 ? 18.179 80.965 -41.096 1.00 21.63 ? 281 THR B O 1 ATOM 1643 C CB . THR A 1 225 ? 17.546 79.529 -43.788 1.00 14.99 ? 281 THR B CB 1 ATOM 1644 O OG1 . THR A 1 225 ? 18.681 79.840 -44.621 1.00 9.65 ? 281 THR B OG1 1 ATOM 1645 C CG2 . THR A 1 225 ? 16.470 78.861 -44.636 1.00 9.75 ? 281 THR B CG2 1 ATOM 1646 N N . ILE A 1 226 ? 18.667 82.475 -42.685 1.00 9.98 ? 282 ILE B N 1 ATOM 1647 C CA . ILE A 1 226 ? 19.681 83.142 -41.879 1.00 17.83 ? 282 ILE B CA 1 ATOM 1648 C C . ILE A 1 226 ? 19.096 83.743 -40.598 1.00 17.13 ? 282 ILE B C 1 ATOM 1649 O O . ILE A 1 226 ? 19.799 83.919 -39.614 1.00 22.68 ? 282 ILE B O 1 ATOM 1650 C CB . ILE A 1 226 ? 20.544 84.114 -42.753 1.00 17.67 ? 282 ILE B CB 1 ATOM 1651 C CG1 . ILE A 1 226 ? 21.611 83.295 -43.481 1.00 24.09 ? 282 ILE B CG1 1 ATOM 1652 C CG2 . ILE A 1 226 ? 21.257 85.160 -41.943 1.00 12.11 ? 282 ILE B CG2 1 ATOM 1653 C CD1 . ILE A 1 226 ? 22.555 84.132 -44.321 1.00 34.94 ? 282 ILE B CD1 1 ATOM 1654 N N . GLY A 1 227 ? 17.790 83.985 -40.586 1.00 19.45 ? 283 GLY B N 1 ATOM 1655 C CA . GLY A 1 227 ? 17.129 84.493 -39.394 1.00 14.24 ? 283 GLY B CA 1 ATOM 1656 C C . GLY A 1 227 ? 17.062 83.492 -38.250 1.00 14.14 ? 283 GLY B C 1 ATOM 1657 O O . GLY A 1 227 ? 16.852 83.858 -37.093 1.00 31.14 ? 283 GLY B O 1 ATOM 1658 N N . GLY A 1 228 ? 17.237 82.217 -38.557 1.00 10.57 ? 284 GLY B N 1 ATOM 1659 C CA . GLY A 1 228 ? 17.172 81.210 -37.519 1.00 2.38 ? 284 GLY B CA 1 ATOM 1660 C C . GLY A 1 228 ? 18.523 80.978 -36.875 1.00 20.62 ? 284 GLY B C 1 ATOM 1661 O O . GLY A 1 228 ? 18.650 80.064 -36.058 1.00 19.34 ? 284 GLY B O 1 ATOM 1662 N N . LEU A 1 229 ? 19.529 81.789 -37.223 1.00 10.15 ? 285 LEU B N 1 ATOM 1663 C CA . LEU A 1 229 ? 20.840 81.636 -36.599 1.00 6.86 ? 285 LEU B CA 1 ATOM 1664 C C . LEU A 1 229 ? 20.903 82.564 -35.383 1.00 10.96 ? 285 LEU B C 1 ATOM 1665 O O . LEU A 1 229 ? 21.185 83.753 -35.522 1.00 12.14 ? 285 LEU B O 1 ATOM 1666 C CB . LEU A 1 229 ? 21.928 82.070 -37.593 1.00 4.95 ? 285 LEU B CB 1 ATOM 1667 C CG . LEU A 1 229 ? 22.057 81.295 -38.909 1.00 10.56 ? 285 LEU B CG 1 ATOM 1668 C CD1 . LEU A 1 229 ? 23.112 81.894 -39.836 1.00 10.93 ? 285 LEU B CD1 1 ATOM 1669 C CD2 . LEU A 1 229 ? 22.376 79.844 -38.646 1.00 9.13 ? 285 LEU B CD2 1 ATOM 1670 N N . LYS A 1 230 ? 20.752 82.010 -34.186 1.00 11.58 ? 286 LYS B N 1 ATOM 1671 C CA . LYS A 1 230 ? 20.575 82.844 -32.982 1.00 12.74 ? 286 LYS B CA 1 ATOM 1672 C C . LYS A 1 230 ? 21.886 83.401 -32.410 1.00 12.37 ? 286 LYS B C 1 ATOM 1673 O O . LYS A 1 230 ? 21.871 84.351 -31.628 1.00 14.47 ? 286 LYS B O 1 ATOM 1674 C CB . LYS A 1 230 ? 19.780 82.098 -31.879 1.00 4.49 ? 286 LYS B CB 1 ATOM 1675 C CG . LYS A 1 230 ? 18.333 81.704 -32.260 1.00 9.96 ? 286 LYS B CG 1 ATOM 1676 C CD . LYS A 1 230 ? 17.599 82.880 -32.923 1.00 20.91 ? 286 LYS B CD 1 ATOM 1677 C CE . LYS A 1 230 ? 16.082 82.668 -33.084 1.00 20.73 ? 286 LYS B CE 1 ATOM 1678 N NZ . LYS A 1 230 ? 15.681 82.215 -34.460 1.00 23.36 ? 286 LYS B NZ 1 ATOM 1679 N N . LYS A 1 231 ? 23.016 82.819 -32.795 1.00 8.09 ? 287 LYS B N 1 ATOM 1680 C CA . LYS A 1 231 ? 24.290 83.285 -32.284 1.00 9.65 ? 287 LYS B CA 1 ATOM 1681 C C . LYS A 1 231 ? 24.968 84.285 -33.216 1.00 7.30 ? 287 LYS B C 1 ATOM 1682 O O . LYS A 1 231 ? 26.085 84.713 -32.944 1.00 15.19 ? 287 LYS B O 1 ATOM 1683 C CB . LYS A 1 231 ? 25.241 82.116 -32.018 1.00 21.38 ? 287 LYS B CB 1 ATOM 1684 C CG . LYS A 1 231 ? 24.685 80.996 -31.160 1.00 25.29 ? 287 LYS B CG 1 ATOM 1685 C CD . LYS A 1 231 ? 24.373 81.452 -29.755 1.00 33.00 ? 287 LYS B CD 1 ATOM 1686 C CE . LYS A 1 231 ? 24.000 80.256 -28.880 1.00 38.54 ? 287 LYS B CE 1 ATOM 1687 N NZ . LYS A 1 231 ? 25.142 79.289 -28.750 1.00 37.40 ? 287 LYS B NZ 1 ATOM 1688 N N . LEU A 1 232 ? 24.303 84.657 -34.309 1.00 8.45 ? 288 LEU B N 1 ATOM 1689 C CA . LEU A 1 232 ? 24.924 85.516 -35.328 1.00 14.68 ? 288 LEU B CA 1 ATOM 1690 C C . LEU A 1 232 ? 25.223 86.928 -34.815 1.00 15.44 ? 288 LEU B C 1 ATOM 1691 O O . LEU A 1 232 ? 24.370 87.600 -34.230 1.00 15.44 ? 288 LEU B O 1 ATOM 1692 C CB . LEU A 1 232 ? 24.057 85.592 -36.579 1.00 10.00 ? 288 LEU B CB 1 ATOM 1693 C CG . LEU A 1 232 ? 24.677 86.152 -37.866 1.00 7.85 ? 288 LEU B CG 1 ATOM 1694 C CD1 . LEU A 1 232 ? 25.739 85.224 -38.440 1.00 6.39 ? 288 LEU B CD1 1 ATOM 1695 C CD2 . LEU A 1 232 ? 23.588 86.385 -38.896 1.00 4.24 ? 288 LEU B CD2 1 ATOM 1696 N N . GLN A 1 233 ? 26.448 87.367 -35.055 1.00 5.97 ? 289 GLN B N 1 ATOM 1697 C CA . GLN A 1 233 ? 26.943 88.643 -34.541 1.00 14.69 ? 289 GLN B CA 1 ATOM 1698 C C . GLN A 1 233 ? 27.294 89.569 -35.701 1.00 11.74 ? 289 GLN B C 1 ATOM 1699 O O . GLN A 1 233 ? 26.878 90.728 -35.734 1.00 16.69 ? 289 GLN B O 1 ATOM 1700 C CB . GLN A 1 233 ? 28.103 88.447 -33.547 1.00 2.88 ? 289 GLN B CB 1 ATOM 1701 C CG . GLN A 1 233 ? 27.809 87.305 -32.575 1.00 30.52 ? 289 GLN B CG 1 ATOM 1702 C CD . GLN A 1 233 ? 28.607 87.327 -31.278 1.00 22.51 ? 289 GLN B CD 1 ATOM 1703 O OE1 . GLN A 1 233 ? 29.773 87.718 -31.248 1.00 17.91 ? 289 GLN B OE1 1 ATOM 1704 N NE2 . GLN A 1 233 ? 27.971 86.880 -30.195 1.00 25.01 ? 289 GLN B NE2 1 ATOM 1705 N N . SER A 1 234 ? 28.140 89.084 -36.597 1.00 7.20 ? 290 SER B N 1 ATOM 1706 C CA . SER A 1 234 ? 28.596 89.912 -37.698 1.00 16.29 ? 290 SER B CA 1 ATOM 1707 C C . SER A 1 234 ? 28.318 89.250 -39.039 1.00 17.23 ? 290 SER B C 1 ATOM 1708 O O . SER A 1 234 ? 28.576 88.060 -39.227 1.00 19.64 ? 290 SER B O 1 ATOM 1709 C CB . SER A 1 234 ? 30.082 90.188 -37.544 1.00 11.38 ? 290 SER B CB 1 ATOM 1710 O OG . SER A 1 234 ? 30.777 88.957 -37.485 1.00 16.23 ? 290 SER B OG 1 ATOM 1711 N N . LEU A 1 235 ? 27.765 90.034 -39.955 1.00 2.70 ? 291 LEU B N 1 ATOM 1712 C CA . LEU A 1 235 ? 27.407 89.563 -41.291 1.00 9.76 ? 291 LEU B CA 1 ATOM 1713 C C . LEU A 1 235 ? 28.002 90.539 -42.318 1.00 13.67 ? 291 LEU B C 1 ATOM 1714 O O . LEU A 1 235 ? 27.565 91.690 -42.408 1.00 6.18 ? 291 LEU B O 1 ATOM 1715 C CB . LEU A 1 235 ? 25.889 89.531 -41.406 1.00 2.24 ? 291 LEU B CB 1 ATOM 1716 C CG . LEU A 1 235 ? 25.222 88.804 -42.568 1.00 14.90 ? 291 LEU B CG 1 ATOM 1717 C CD1 . LEU A 1 235 ? 25.702 87.364 -42.650 1.00 13.65 ? 291 LEU B CD1 1 ATOM 1718 C CD2 . LEU A 1 235 ? 23.707 88.847 -42.400 1.00 2.92 ? 291 LEU B CD2 1 ATOM 1719 N N . LEU A 1 236 ? 29.016 90.101 -43.063 1.00 6.81 ? 292 LEU B N 1 ATOM 1720 C CA . LEU A 1 236 ? 29.552 90.946 -44.113 1.00 6.35 ? 292 LEU B CA 1 ATOM 1721 C C . LEU A 1 236 ? 29.325 90.311 -45.467 1.00 7.58 ? 292 LEU B C 1 ATOM 1722 O O . LEU A 1 236 ? 29.989 89.348 -45.834 1.00 12.80 ? 292 LEU B O 1 ATOM 1723 C CB . LEU A 1 236 ? 31.043 91.174 -43.894 1.00 10.35 ? 292 LEU B CB 1 ATOM 1724 C CG . LEU A 1 236 ? 31.418 91.816 -42.558 1.00 6.59 ? 292 LEU B CG 1 ATOM 1725 C CD1 . LEU A 1 236 ? 32.924 91.928 -42.437 1.00 5.31 ? 292 LEU B CD1 1 ATOM 1726 C CD2 . LEU A 1 236 ? 30.793 93.188 -42.419 1.00 4.47 ? 292 LEU B CD2 1 ATOM 1727 N N . LEU A 1 237 ? 28.406 90.837 -46.231 1.00 11.85 ? 293 LEU B N 1 ATOM 1728 C CA . LEU A 1 237 ? 28.118 90.380 -47.571 1.00 10.92 ? 293 LEU B CA 1 ATOM 1729 C C . LEU A 1 237 ? 28.323 91.475 -48.569 1.00 12.69 ? 293 LEU B C 1 ATOM 1730 O O . LEU A 1 237 ? 27.789 91.417 -49.607 1.00 8.17 ? 293 LEU B O 1 ATOM 1731 C CB . LEU A 1 237 ? 26.679 89.882 -47.687 1.00 5.58 ? 293 LEU B CB 1 ATOM 1732 C CG . LEU A 1 237 ? 26.250 88.736 -46.807 1.00 11.08 ? 293 LEU B CG 1 ATOM 1733 C CD1 . LEU A 1 237 ? 24.855 88.373 -46.909 1.00 2.63 ? 293 LEU B CD1 1 ATOM 1734 C CD2 . LEU A 1 237 ? 27.089 87.587 -47.026 1.00 9.34 ? 293 LEU B CD2 1 ATOM 1735 N N . TRP A 1 238 ? 29.068 92.499 -48.228 1.00 14.22 ? 294 TRP B N 1 ATOM 1736 C CA . TRP A 1 238 ? 29.251 93.612 -49.115 1.00 14.05 ? 294 TRP B CA 1 ATOM 1737 C C . TRP A 1 238 ? 30.035 93.308 -50.373 1.00 13.25 ? 294 TRP B C 1 ATOM 1738 O O . TRP A 1 238 ? 30.920 92.533 -50.371 1.00 19.07 ? 294 TRP B O 1 ATOM 1739 C CB . TRP A 1 238 ? 29.795 94.863 -48.413 1.00 3.14 ? 294 TRP B CB 1 ATOM 1740 C CG . TRP A 1 238 ? 31.091 94.718 -47.864 1.00 3.71 ? 294 TRP B CG 1 ATOM 1741 C CD1 . TRP A 1 238 ? 31.371 94.157 -46.721 1.00 16.17 ? 294 TRP B CD1 1 ATOM 1742 C CD2 . TRP A 1 238 ? 32.318 95.122 -48.418 1.00 7.44 ? 294 TRP B CD2 1 ATOM 1743 N NE1 . TRP A 1 238 ? 32.656 94.158 -46.495 1.00 15.26 ? 294 TRP B NE1 1 ATOM 1744 C CE2 . TRP A 1 238 ? 33.286 94.763 -47.528 1.00 11.66 ? 294 TRP B CE2 1 ATOM 1745 C CE3 . TRP A 1 238 ? 32.695 95.752 -49.594 1.00 9.30 ? 294 TRP B CE3 1 ATOM 1746 C CZ2 . TRP A 1 238 ? 34.618 94.989 -47.750 1.00 5.30 ? 294 TRP B CZ2 1 ATOM 1747 C CZ3 . TRP A 1 238 ? 33.998 95.985 -49.810 1.00 4.86 ? 294 TRP B CZ3 1 ATOM 1748 C CH2 . TRP A 1 238 ? 34.953 95.618 -48.889 1.00 8.64 ? 294 TRP B CH2 1 ATOM 1749 N N . GLN A 1 239 ? 29.691 94.016 -51.430 1.00 24.31 ? 295 GLN B N 1 ATOM 1750 C CA . GLN A 1 239 ? 30.263 93.873 -52.760 1.00 21.72 ? 295 GLN B CA 1 ATOM 1751 C C . GLN A 1 239 ? 30.141 92.528 -53.493 1.00 15.44 ? 295 GLN B C 1 ATOM 1752 O O . GLN A 1 239 ? 31.066 91.883 -53.771 1.00 4.71 ? 295 GLN B O 1 ATOM 1753 C CB . GLN A 1 239 ? 31.686 94.360 -52.743 1.00 21.95 ? 295 GLN B CB 1 ATOM 1754 C CG . GLN A 1 239 ? 32.139 94.860 -53.990 1.00 28.23 ? 295 GLN B CG 1 ATOM 1755 C CD . GLN A 1 239 ? 33.451 95.524 -53.910 1.00 35.31 ? 295 GLN B CD 1 ATOM 1756 O OE1 . GLN A 1 239 ? 33.555 96.657 -53.482 1.00 37.32 ? 295 GLN B OE1 1 ATOM 1757 N NE2 . GLN A 1 239 ? 34.455 94.864 -54.383 1.00 33.54 ? 295 GLN B NE2 1 ATOM 1758 N N . ASN A 1 240 ? 28.914 92.143 -53.705 1.00 15.67 ? 296 ASN B N 1 ATOM 1759 C CA . ASN A 1 240 ? 28.478 90.996 -54.461 1.00 14.57 ? 296 ASN B CA 1 ATOM 1760 C C . ASN A 1 240 ? 27.417 91.392 -55.489 1.00 8.59 ? 296 ASN B C 1 ATOM 1761 O O . ASN A 1 240 ? 27.313 92.514 -55.838 1.00 12.41 ? 296 ASN B O 1 ATOM 1762 C CB . ASN A 1 240 ? 27.967 89.907 -53.521 1.00 3.88 ? 296 ASN B CB 1 ATOM 1763 C CG . ASN A 1 240 ? 29.044 89.238 -52.765 1.00 8.16 ? 296 ASN B CG 1 ATOM 1764 O OD1 . ASN A 1 240 ? 29.731 88.423 -53.267 1.00 8.38 ? 296 ASN B OD1 1 ATOM 1765 N ND2 . ASN A 1 240 ? 29.140 89.546 -51.530 1.00 4.22 ? 296 ASN B ND2 1 ATOM 1766 N N . ASN A 1 241 ? 26.691 90.421 -56.006 1.00 7.37 ? 297 ASN B N 1 ATOM 1767 C CA . ASN A 1 241 ? 25.558 90.577 -56.916 1.00 10.43 ? 297 ASN B CA 1 ATOM 1768 C C . ASN A 1 241 ? 24.193 90.337 -56.313 1.00 16.14 ? 297 ASN B C 1 ATOM 1769 O O . ASN A 1 241 ? 23.262 89.994 -57.037 1.00 17.40 ? 297 ASN B O 1 ATOM 1770 C CB . ASN A 1 241 ? 25.777 89.814 -58.208 1.00 3.83 ? 297 ASN B CB 1 ATOM 1771 C CG . ASN A 1 241 ? 26.985 90.322 -58.951 1.00 5.25 ? 297 ASN B CG 1 ATOM 1772 O OD1 . ASN A 1 241 ? 27.113 91.518 -59.174 1.00 10.49 ? 297 ASN B OD1 1 ATOM 1773 N ND2 . ASN A 1 241 ? 27.905 89.431 -59.281 1.00 12.43 ? 297 ASN B ND2 1 ATOM 1774 N N . LEU A 1 242 ? 24.118 90.342 -54.985 1.00 15.47 ? 298 LEU B N 1 ATOM 1775 C CA . LEU A 1 242 ? 22.887 89.972 -54.282 1.00 11.92 ? 298 LEU B CA 1 ATOM 1776 C C . LEU A 1 242 ? 21.631 90.744 -54.685 1.00 3.45 ? 298 LEU B C 1 ATOM 1777 O O . LEU A 1 242 ? 21.646 91.946 -54.869 1.00 7.00 ? 298 LEU B O 1 ATOM 1778 C CB . LEU A 1 242 ? 23.087 90.023 -52.772 1.00 2.47 ? 298 LEU B CB 1 ATOM 1779 C CG . LEU A 1 242 ? 24.065 88.999 -52.195 1.00 13.51 ? 298 LEU B CG 1 ATOM 1780 C CD1 . LEU A 1 242 ? 24.507 89.427 -50.809 1.00 14.11 ? 298 LEU B CD1 1 ATOM 1781 C CD2 . LEU A 1 242 ? 23.429 87.628 -52.134 1.00 2.93 ? 298 LEU B CD2 1 ATOM 1782 N N . VAL A 1 243 ? 20.532 90.018 -54.758 1.00 10.57 ? 299 VAL B N 1 ATOM 1783 C CA . VAL A 1 243 ? 19.316 90.471 -55.413 1.00 12.96 ? 299 VAL B CA 1 ATOM 1784 C C . VAL A 1 243 ? 18.150 90.205 -54.459 1.00 12.24 ? 299 VAL B C 1 ATOM 1785 O O . VAL A 1 243 ? 18.311 89.452 -53.512 1.00 15.54 ? 299 VAL B O 1 ATOM 1786 C CB . VAL A 1 243 ? 19.199 89.675 -56.745 1.00 18.91 ? 299 VAL B CB 1 ATOM 1787 C CG1 . VAL A 1 243 ? 17.953 88.795 -56.815 1.00 6.30 ? 299 VAL B CG1 1 ATOM 1788 C CG2 . VAL A 1 243 ? 19.384 90.581 -57.925 1.00 2.55 ? 299 VAL B CG2 1 ATOM 1789 N N . GLY A 1 244 ? 17.003 90.836 -54.671 1.00 9.85 ? 300 GLY B N 1 ATOM 1790 C CA . GLY A 1 244 ? 15.826 90.579 -53.849 1.00 2.20 ? 300 GLY B CA 1 ATOM 1791 C C . GLY A 1 244 ? 15.761 91.448 -52.601 1.00 13.30 ? 300 GLY B C 1 ATOM 1792 O O . GLY A 1 244 ? 16.528 92.399 -52.458 1.00 22.07 ? 300 GLY B O 1 ATOM 1793 N N . LYS A 1 245 ? 14.858 91.118 -51.684 1.00 9.43 ? 301 LYS B N 1 ATOM 1794 C CA . LYS A 1 245 ? 14.656 91.929 -50.480 1.00 17.19 ? 301 LYS B CA 1 ATOM 1795 C C . LYS A 1 245 ? 15.462 91.423 -49.278 1.00 19.76 ? 301 LYS B C 1 ATOM 1796 O O . LYS A 1 245 ? 15.776 90.237 -49.179 1.00 25.66 ? 301 LYS B O 1 ATOM 1797 C CB . LYS A 1 245 ? 13.159 92.061 -50.124 1.00 19.60 ? 301 LYS B CB 1 ATOM 1798 C CG . LYS A 1 245 ? 12.517 90.829 -49.510 1.00 23.91 ? 301 LYS B CG 1 ATOM 1799 C CD . LYS A 1 245 ? 10.989 90.964 -49.425 1.00 38.39 ? 301 LYS B CD 1 ATOM 1800 C CE . LYS A 1 245 ? 10.370 91.077 -50.824 1.00 47.14 ? 301 LYS B CE 1 ATOM 1801 N NZ . LYS A 1 245 ? 8.886 91.246 -50.836 1.00 46.48 ? 301 LYS B NZ 1 ATOM 1802 N N . ILE A 1 246 ? 15.856 92.347 -48.409 1.00 13.73 ? 302 ILE B N 1 ATOM 1803 C CA . ILE A 1 246 ? 16.423 91.993 -47.118 1.00 11.17 ? 302 ILE B CA 1 ATOM 1804 C C . ILE A 1 246 ? 15.424 91.187 -46.283 1.00 9.61 ? 302 ILE B C 1 ATOM 1805 O O . ILE A 1 246 ? 14.308 91.624 -46.045 1.00 11.22 ? 302 ILE B O 1 ATOM 1806 C CB . ILE A 1 246 ? 16.819 93.237 -46.347 1.00 9.74 ? 302 ILE B CB 1 ATOM 1807 C CG1 . ILE A 1 246 ? 17.817 94.049 -47.166 1.00 9.56 ? 302 ILE B CG1 1 ATOM 1808 C CG2 . ILE A 1 246 ? 17.391 92.854 -44.983 1.00 11.51 ? 302 ILE B CG2 1 ATOM 1809 C CD1 . ILE A 1 246 ? 18.175 95.397 -46.545 1.00 13.09 ? 302 ILE B CD1 1 ATOM 1810 N N . PRO A 1 247 ? 15.822 89.987 -45.857 1.00 9.72 ? 303 PRO B N 1 ATOM 1811 C CA . PRO A 1 247 ? 14.894 89.136 -45.111 1.00 5.71 ? 303 PRO B CA 1 ATOM 1812 C C . PRO A 1 247 ? 14.479 89.765 -43.771 1.00 10.97 ? 303 PRO B C 1 ATOM 1813 O O . PRO A 1 247 ? 15.287 90.157 -42.956 1.00 10.14 ? 303 PRO B O 1 ATOM 1814 C CB . PRO A 1 247 ? 15.711 87.863 -44.854 1.00 2.00 ? 303 PRO B CB 1 ATOM 1815 C CG . PRO A 1 247 ? 16.887 87.934 -45.780 1.00 12.81 ? 303 PRO B CG 1 ATOM 1816 C CD . PRO A 1 247 ? 17.156 89.379 -46.003 1.00 8.04 ? 303 PRO B CD 1 ATOM 1817 N N . THR A 1 248 ? 13.188 89.833 -43.554 1.00 16.53 ? 304 THR B N 1 ATOM 1818 C CA . THR A 1 248 ? 12.627 90.291 -42.305 1.00 14.98 ? 304 THR B CA 1 ATOM 1819 C C . THR A 1 248 ? 13.183 89.502 -41.114 1.00 16.33 ? 304 THR B C 1 ATOM 1820 O O . THR A 1 248 ? 13.419 90.046 -40.018 1.00 11.09 ? 304 THR B O 1 ATOM 1821 C CB . THR A 1 248 ? 11.116 90.127 -42.411 1.00 12.42 ? 304 THR B CB 1 ATOM 1822 O OG1 . THR A 1 248 ? 10.577 91.300 -43.043 1.00 16.72 ? 304 THR B OG1 1 ATOM 1823 C CG2 . THR A 1 248 ? 10.504 89.918 -41.084 1.00 6.49 ? 304 THR B CG2 1 ATOM 1824 N N . GLU A 1 249 ? 13.445 88.222 -41.349 1.00 6.26 ? 305 GLU B N 1 ATOM 1825 C CA . GLU A 1 249 ? 13.846 87.352 -40.263 1.00 2.68 ? 305 GLU B CA 1 ATOM 1826 C C . GLU A 1 249 ? 15.220 87.681 -39.662 1.00 9.10 ? 305 GLU B C 1 ATOM 1827 O O . GLU A 1 249 ? 15.550 87.184 -38.581 1.00 9.78 ? 305 GLU B O 1 ATOM 1828 C CB . GLU A 1 249 ? 13.760 85.888 -40.682 1.00 2.00 ? 305 GLU B CB 1 ATOM 1829 C CG . GLU A 1 249 ? 12.337 85.385 -40.786 1.00 10.86 ? 305 GLU B CG 1 ATOM 1830 C CD . GLU A 1 249 ? 11.719 85.633 -42.142 1.00 17.07 ? 305 GLU B CD 1 ATOM 1831 O OE1 . GLU A 1 249 ? 12.435 86.132 -43.031 1.00 16.00 ? 305 GLU B OE1 1 ATOM 1832 O OE2 . GLU A 1 249 ? 10.520 85.331 -42.321 1.00 20.65 ? 305 GLU B OE2 1 ATOM 1833 N N . LEU A 1 250 ? 16.009 88.517 -40.341 1.00 5.70 ? 306 LEU B N 1 ATOM 1834 C CA . LEU A 1 250 ? 17.270 89.011 -39.775 1.00 6.08 ? 306 LEU B CA 1 ATOM 1835 C C . LEU A 1 250 ? 17.032 89.725 -38.455 1.00 20.68 ? 306 LEU B C 1 ATOM 1836 O O . LEU A 1 250 ? 17.880 89.697 -37.565 1.00 25.77 ? 306 LEU B O 1 ATOM 1837 C CB . LEU A 1 250 ? 17.976 89.963 -40.724 1.00 9.81 ? 306 LEU B CB 1 ATOM 1838 C CG . LEU A 1 250 ? 18.938 89.236 -41.645 1.00 24.15 ? 306 LEU B CG 1 ATOM 1839 C CD1 . LEU A 1 250 ? 19.600 90.202 -42.589 1.00 31.95 ? 306 LEU B CD1 1 ATOM 1840 C CD2 . LEU A 1 250 ? 19.963 88.521 -40.795 1.00 29.38 ? 306 LEU B CD2 1 ATOM 1841 N N . GLY A 1 251 ? 15.863 90.341 -38.312 1.00 12.62 ? 307 GLY B N 1 ATOM 1842 C CA . GLY A 1 251 ? 15.536 90.966 -37.050 1.00 12.35 ? 307 GLY B CA 1 ATOM 1843 C C . GLY A 1 251 ? 15.322 89.990 -35.899 1.00 14.88 ? 307 GLY B C 1 ATOM 1844 O O . GLY A 1 251 ? 14.995 90.410 -34.798 1.00 17.84 ? 307 GLY B O 1 ATOM 1845 N N . ASN A 1 252 ? 15.483 88.693 -36.149 1.00 16.09 ? 308 ASN B N 1 ATOM 1846 C CA . ASN A 1 252 ? 15.367 87.683 -35.088 1.00 22.92 ? 308 ASN B CA 1 ATOM 1847 C C . ASN A 1 252 ? 16.685 87.202 -34.484 1.00 23.57 ? 308 ASN B C 1 ATOM 1848 O O . ASN A 1 252 ? 16.682 86.317 -33.632 1.00 29.91 ? 308 ASN B O 1 ATOM 1849 C CB . ASN A 1 252 ? 14.563 86.470 -35.561 1.00 21.99 ? 308 ASN B CB 1 ATOM 1850 C CG . ASN A 1 252 ? 13.153 86.830 -35.947 1.00 25.59 ? 308 ASN B CG 1 ATOM 1851 O OD1 . ASN A 1 252 ? 12.543 87.716 -35.343 1.00 25.92 ? 308 ASN B OD1 1 ATOM 1852 N ND2 . ASN A 1 252 ? 12.625 86.155 -36.973 1.00 26.39 ? 308 ASN B ND2 1 ATOM 1853 N N . CYS A 1 253 ? 17.806 87.755 -34.936 1.00 21.37 ? 309 CYS B N 1 ATOM 1854 C CA . CYS A 1 253 ? 19.086 87.416 -34.327 1.00 21.93 ? 309 CYS B CA 1 ATOM 1855 C C . CYS A 1 253 ? 19.450 88.434 -33.235 1.00 15.95 ? 309 CYS B C 1 ATOM 1856 O O . CYS A 1 253 ? 19.942 89.522 -33.515 1.00 6.34 ? 309 CYS B O 1 ATOM 1857 C CB . CYS A 1 253 ? 20.172 87.387 -35.402 1.00 25.37 ? 309 CYS B CB 1 ATOM 1858 S SG . CYS A 1 253 ? 19.684 86.539 -36.939 1.00 19.13 ? 309 CYS B SG 1 ATOM 1859 N N . PRO A 1 254 ? 19.254 88.053 -31.973 1.00 12.71 ? 310 PRO B N 1 ATOM 1860 C CA . PRO A 1 254 ? 19.410 89.007 -30.878 1.00 9.79 ? 310 PRO B CA 1 ATOM 1861 C C . PRO A 1 254 ? 20.832 89.549 -30.767 1.00 19.66 ? 310 PRO B C 1 ATOM 1862 O O . PRO A 1 254 ? 21.033 90.656 -30.263 1.00 25.55 ? 310 PRO B O 1 ATOM 1863 C CB . PRO A 1 254 ? 19.087 88.159 -29.636 1.00 9.96 ? 310 PRO B CB 1 ATOM 1864 C CG . PRO A 1 254 ? 18.228 87.075 -30.130 1.00 11.40 ? 310 PRO B CG 1 ATOM 1865 C CD . PRO A 1 254 ? 18.743 86.753 -31.507 1.00 10.94 ? 310 PRO B CD 1 ATOM 1866 N N . GLU A 1 255 ? 21.812 88.777 -31.218 1.00 17.46 ? 311 GLU B N 1 ATOM 1867 C CA . GLU A 1 255 ? 23.204 89.107 -30.923 1.00 11.63 ? 311 GLU B CA 1 ATOM 1868 C C . GLU A 1 255 ? 23.892 89.890 -32.038 1.00 12.50 ? 311 GLU B C 1 ATOM 1869 O O . GLU A 1 255 ? 25.088 90.143 -31.970 1.00 16.77 ? 311 GLU B O 1 ATOM 1870 C CB . GLU A 1 255 ? 23.991 87.840 -30.575 1.00 15.10 ? 311 GLU B CB 1 ATOM 1871 C CG . GLU A 1 255 ? 23.504 87.154 -29.319 1.00 21.13 ? 311 GLU B CG 1 ATOM 1872 C CD . GLU A 1 255 ? 23.606 88.063 -28.130 1.00 46.64 ? 311 GLU B CD 1 ATOM 1873 O OE1 . GLU A 1 255 ? 24.608 88.807 -28.050 1.00 57.49 ? 311 GLU B OE1 1 ATOM 1874 O OE2 . GLU A 1 255 ? 22.684 88.058 -27.285 1.00 54.43 ? 311 GLU B OE2 1 ATOM 1875 N N . LEU A 1 256 ? 23.134 90.276 -33.060 1.00 10.36 ? 312 LEU B N 1 ATOM 1876 C CA . LEU A 1 256 ? 23.725 90.814 -34.273 1.00 10.77 ? 312 LEU B CA 1 ATOM 1877 C C . LEU A 1 256 ? 24.128 92.253 -34.060 1.00 9.29 ? 312 LEU B C 1 ATOM 1878 O O . LEU A 1 256 ? 23.280 93.103 -33.785 1.00 3.02 ? 312 LEU B O 1 ATOM 1879 C CB . LEU A 1 256 ? 22.678 90.746 -35.377 1.00 11.30 ? 312 LEU B CB 1 ATOM 1880 C CG . LEU A 1 256 ? 23.024 90.874 -36.850 1.00 12.78 ? 312 LEU B CG 1 ATOM 1881 C CD1 . LEU A 1 256 ? 24.138 89.935 -37.214 1.00 2.00 ? 312 LEU B CD1 1 ATOM 1882 C CD2 . LEU A 1 256 ? 21.781 90.520 -37.647 1.00 12.00 ? 312 LEU B CD2 1 ATOM 1883 N N . TRP A 1 257 ? 25.428 92.531 -34.126 1.00 7.73 ? 313 TRP B N 1 ATOM 1884 C CA . TRP A 1 257 ? 25.878 93.913 -33.985 1.00 10.56 ? 313 TRP B CA 1 ATOM 1885 C C . TRP A 1 257 ? 26.391 94.622 -35.244 1.00 14.39 ? 313 TRP B C 1 ATOM 1886 O O . TRP A 1 257 ? 26.528 95.852 -35.246 1.00 16.23 ? 313 TRP B O 1 ATOM 1887 C CB . TRP A 1 257 ? 26.922 94.007 -32.873 1.00 6.14 ? 313 TRP B CB 1 ATOM 1888 C CG . TRP A 1 257 ? 28.239 93.424 -33.258 1.00 9.52 ? 313 TRP B CG 1 ATOM 1889 C CD1 . TRP A 1 257 ? 28.611 92.110 -33.171 1.00 3.81 ? 313 TRP B CD1 1 ATOM 1890 C CD2 . TRP A 1 257 ? 29.362 94.128 -33.793 1.00 2.41 ? 313 TRP B CD2 1 ATOM 1891 N NE1 . TRP A 1 257 ? 29.897 91.955 -33.633 1.00 3.59 ? 313 TRP B NE1 1 ATOM 1892 C CE2 . TRP A 1 257 ? 30.387 93.179 -34.009 1.00 3.05 ? 313 TRP B CE2 1 ATOM 1893 C CE3 . TRP A 1 257 ? 29.615 95.467 -34.092 1.00 7.97 ? 313 TRP B CE3 1 ATOM 1894 C CZ2 . TRP A 1 257 ? 31.634 93.527 -34.520 1.00 3.63 ? 313 TRP B CZ2 1 ATOM 1895 C CZ3 . TRP A 1 257 ? 30.865 95.818 -34.587 1.00 2.92 ? 313 TRP B CZ3 1 ATOM 1896 C CH2 . TRP A 1 257 ? 31.857 94.846 -34.798 1.00 7.20 ? 313 TRP B CH2 1 ATOM 1897 N N . LEU A 1 258 ? 26.636 93.870 -36.317 1.00 15.18 ? 314 LEU B N 1 ATOM 1898 C CA . LEU A 1 258 ? 27.155 94.450 -37.565 1.00 9.90 ? 314 LEU B CA 1 ATOM 1899 C C . LEU A 1 258 ? 26.507 93.812 -38.792 1.00 12.88 ? 314 LEU B C 1 ATOM 1900 O O . LEU A 1 258 ? 26.561 92.586 -38.952 1.00 18.57 ? 314 LEU B O 1 ATOM 1901 C CB . LEU A 1 258 ? 28.687 94.335 -37.659 1.00 2.15 ? 314 LEU B CB 1 ATOM 1902 C CG . LEU A 1 258 ? 29.288 94.658 -39.046 1.00 10.21 ? 314 LEU B CG 1 ATOM 1903 C CD1 . LEU A 1 258 ? 28.965 96.053 -39.495 1.00 9.00 ? 314 LEU B CD1 1 ATOM 1904 C CD2 . LEU A 1 258 ? 30.786 94.476 -39.077 1.00 10.28 ? 314 LEU B CD2 1 ATOM 1905 N N . ILE A 1 259 ? 25.899 94.646 -39.642 1.00 5.57 ? 315 ILE B N 1 ATOM 1906 C CA . ILE A 1 259 ? 25.308 94.186 -40.895 1.00 9.11 ? 315 ILE B CA 1 ATOM 1907 C C . ILE A 1 259 ? 25.831 95.018 -42.075 1.00 8.30 ? 315 ILE B C 1 ATOM 1908 O O . ILE A 1 259 ? 25.540 96.211 -42.177 1.00 9.88 ? 315 ILE B O 1 ATOM 1909 C CB . ILE A 1 259 ? 23.773 94.339 -40.844 1.00 15.96 ? 315 ILE B CB 1 ATOM 1910 C CG1 . ILE A 1 259 ? 23.163 93.442 -39.766 1.00 13.00 ? 315 ILE B CG1 1 ATOM 1911 C CG2 . ILE A 1 259 ? 23.147 94.042 -42.203 1.00 11.74 ? 315 ILE B CG2 1 ATOM 1912 C CD1 . ILE A 1 259 ? 21.639 93.609 -39.644 1.00 11.25 ? 315 ILE B CD1 1 ATOM 1913 N N . ASP A 1 260 ? 26.624 94.418 -42.950 1.00 7.09 ? 316 ASP B N 1 ATOM 1914 C CA . ASP A 1 260 ? 27.082 95.156 -44.123 1.00 11.84 ? 316 ASP B CA 1 ATOM 1915 C C . ASP A 1 260 ? 26.669 94.449 -45.409 1.00 16.58 ? 316 ASP B C 1 ATOM 1916 O O . ASP A 1 260 ? 27.207 93.395 -45.754 1.00 11.72 ? 316 ASP B O 1 ATOM 1917 C CB . ASP A 1 260 ? 28.590 95.326 -44.087 1.00 7.59 ? 316 ASP B CB 1 ATOM 1918 C CG . ASP A 1 260 ? 29.065 96.449 -44.978 1.00 12.86 ? 316 ASP B CG 1 ATOM 1919 O OD1 . ASP A 1 260 ? 28.359 96.764 -45.949 1.00 16.89 ? 316 ASP B OD1 1 ATOM 1920 O OD2 . ASP A 1 260 ? 30.137 97.027 -44.706 1.00 7.95 ? 316 ASP B OD2 1 ATOM 1921 N N . PHE A 1 261 ? 25.663 95.027 -46.062 1.00 15.47 ? 317 PHE B N 1 ATOM 1922 C CA . PHE A 1 261 ? 25.157 94.625 -47.380 1.00 16.57 ? 317 PHE B CA 1 ATOM 1923 C C . PHE A 1 261 ? 25.553 95.579 -48.510 1.00 19.88 ? 317 PHE B C 1 ATOM 1924 O O . PHE A 1 261 ? 25.000 95.505 -49.600 1.00 13.46 ? 317 PHE B O 1 ATOM 1925 C CB . PHE A 1 261 ? 23.641 94.408 -47.360 1.00 3.13 ? 317 PHE B CB 1 ATOM 1926 C CG . PHE A 1 261 ? 23.188 93.372 -46.359 1.00 5.41 ? 317 PHE B CG 1 ATOM 1927 C CD1 . PHE A 1 261 ? 24.059 92.397 -45.903 1.00 9.81 ? 317 PHE B CD1 1 ATOM 1928 C CD2 . PHE A 1 261 ? 21.889 93.372 -45.880 1.00 5.25 ? 317 PHE B CD2 1 ATOM 1929 C CE1 . PHE A 1 261 ? 23.645 91.441 -44.983 1.00 11.95 ? 317 PHE B CE1 1 ATOM 1930 C CE2 . PHE A 1 261 ? 21.462 92.416 -44.969 1.00 12.36 ? 317 PHE B CE2 1 ATOM 1931 C CZ . PHE A 1 261 ? 22.346 91.451 -44.518 1.00 15.18 ? 317 PHE B CZ 1 ATOM 1932 N N . SER A 1 262 ? 26.435 96.527 -48.231 1.00 2.00 ? 318 SER B N 1 ATOM 1933 C CA . SER A 1 262 ? 26.761 97.556 -49.205 1.00 14.18 ? 318 SER B CA 1 ATOM 1934 C C . SER A 1 262 ? 27.141 97.021 -50.596 1.00 4.76 ? 318 SER B C 1 ATOM 1935 O O . SER A 1 262 ? 27.691 95.932 -50.721 1.00 10.11 ? 318 SER B O 1 ATOM 1936 C CB . SER A 1 262 ? 27.917 98.409 -48.682 1.00 15.18 ? 318 SER B CB 1 ATOM 1937 O OG . SER A 1 262 ? 27.689 98.775 -47.343 1.00 12.34 ? 318 SER B OG 1 ATOM 1938 N N . GLU A 1 263 ? 26.816 97.798 -51.632 1.00 8.22 ? 319 GLU B N 1 ATOM 1939 C CA . GLU A 1 263 ? 27.218 97.490 -53.022 1.00 11.94 ? 319 GLU B CA 1 ATOM 1940 C C . GLU A 1 263 ? 26.733 96.150 -53.519 1.00 13.84 ? 319 GLU B C 1 ATOM 1941 O O . GLU A 1 263 ? 27.530 95.282 -53.889 1.00 2.76 ? 319 GLU B O 1 ATOM 1942 C CB . GLU A 1 263 ? 28.729 97.606 -53.232 1.00 9.84 ? 319 GLU B CB 1 ATOM 1943 C CG . GLU A 1 263 ? 29.240 99.007 -53.031 1.00 24.85 ? 319 GLU B CG 1 ATOM 1944 C CD . GLU A 1 263 ? 30.509 99.266 -53.784 1.00 45.68 ? 319 GLU B CD 1 ATOM 1945 O OE1 . GLU A 1 263 ? 31.463 99.797 -53.168 1.00 50.97 ? 319 GLU B OE1 1 ATOM 1946 O OE2 . GLU A 1 263 ? 30.544 98.946 -54.997 1.00 53.22 ? 319 GLU B OE2 1 ATOM 1947 N N . ASN A 1 264 ? 25.415 95.995 -53.457 1.00 7.72 ? 320 ASN B N 1 ATOM 1948 C CA . ASN A 1 264 ? 24.707 94.864 -54.026 1.00 6.45 ? 320 ASN B CA 1 ATOM 1949 C C . ASN A 1 264 ? 23.558 95.382 -54.913 1.00 15.21 ? 320 ASN B C 1 ATOM 1950 O O . ASN A 1 264 ? 23.542 96.555 -55.322 1.00 11.21 ? 320 ASN B O 1 ATOM 1951 C CB . ASN A 1 264 ? 24.193 93.923 -52.929 1.00 8.89 ? 320 ASN B CB 1 ATOM 1952 C CG . ASN A 1 264 ? 25.271 92.954 -52.426 1.00 13.47 ? 320 ASN B CG 1 ATOM 1953 O OD1 . ASN A 1 264 ? 25.552 91.947 -53.066 1.00 16.34 ? 320 ASN B OD1 1 ATOM 1954 N ND2 . ASN A 1 264 ? 25.862 93.251 -51.271 1.00 3.93 ? 320 ASN B ND2 1 ATOM 1955 N N . LEU A 1 265 ? 22.686 94.473 -55.321 1.00 9.44 ? 321 LEU B N 1 ATOM 1956 C CA . LEU A 1 265 ? 21.486 94.796 -56.085 1.00 7.17 ? 321 LEU B CA 1 ATOM 1957 C C . LEU A 1 265 ? 20.173 94.773 -55.282 1.00 14.10 ? 321 LEU B C 1 ATOM 1958 O O . LEU A 1 265 ? 19.101 94.639 -55.851 1.00 19.33 ? 321 LEU B O 1 ATOM 1959 C CB . LEU A 1 265 ? 21.419 93.983 -57.383 1.00 15.39 ? 321 LEU B CB 1 ATOM 1960 C CG . LEU A 1 265 ? 22.649 94.184 -58.288 1.00 16.31 ? 321 LEU B CG 1 ATOM 1961 C CD1 . LEU A 1 265 ? 22.752 93.115 -59.388 1.00 10.06 ? 321 LEU B CD1 1 ATOM 1962 C CD2 . LEU A 1 265 ? 22.644 95.571 -58.897 1.00 10.09 ? 321 LEU B CD2 1 ATOM 1963 N N . LEU A 1 266 ? 20.260 94.756 -53.962 1.00 19.16 ? 322 LEU B N 1 ATOM 1964 C CA . LEU A 1 266 ? 19.063 94.647 -53.117 1.00 11.10 ? 322 LEU B CA 1 ATOM 1965 C C . LEU A 1 266 ? 17.936 95.648 -53.401 1.00 8.35 ? 322 LEU B C 1 ATOM 1966 O O . LEU A 1 266 ? 18.178 96.820 -53.657 1.00 8.70 ? 322 LEU B O 1 ATOM 1967 C CB . LEU A 1 266 ? 19.455 94.732 -51.643 1.00 3.84 ? 322 LEU B CB 1 ATOM 1968 C CG . LEU A 1 266 ? 20.521 93.712 -51.246 1.00 3.15 ? 322 LEU B CG 1 ATOM 1969 C CD1 . LEU A 1 266 ? 21.048 93.984 -49.862 1.00 2.00 ? 322 LEU B CD1 1 ATOM 1970 C CD2 . LEU A 1 266 ? 19.911 92.323 -51.324 1.00 2.65 ? 322 LEU B CD2 1 ATOM 1971 N N . THR A 1 267 ? 16.704 95.153 -53.347 1.00 3.33 ? 323 THR B N 1 ATOM 1972 C CA . THR A 1 267 ? 15.507 95.971 -53.430 1.00 3.69 ? 323 THR B CA 1 ATOM 1973 C C . THR A 1 267 ? 14.613 95.708 -52.228 1.00 9.91 ? 323 THR B C 1 ATOM 1974 O O . THR A 1 267 ? 15.003 95.046 -51.271 1.00 21.52 ? 323 THR B O 1 ATOM 1975 C CB . THR A 1 267 ? 14.678 95.649 -54.663 1.00 9.39 ? 323 THR B CB 1 ATOM 1976 O OG1 . THR A 1 267 ? 14.367 94.253 -54.643 1.00 12.13 ? 323 THR B OG1 1 ATOM 1977 C CG2 . THR A 1 267 ? 15.442 95.999 -55.942 1.00 2.00 ? 323 THR B CG2 1 ATOM 1978 N N . GLY A 1 268 ? 13.405 96.247 -52.287 1.00 9.42 ? 324 GLY B N 1 ATOM 1979 C CA . GLY A 1 268 ? 12.484 96.177 -51.175 1.00 5.39 ? 324 GLY B CA 1 ATOM 1980 C C . GLY A 1 268 ? 12.762 97.316 -50.212 1.00 13.88 ? 324 GLY B C 1 ATOM 1981 O O . GLY A 1 268 ? 13.299 98.363 -50.570 1.00 25.39 ? 324 GLY B O 1 ATOM 1982 N N . THR A 1 269 ? 12.450 97.066 -48.960 1.00 11.30 ? 325 THR B N 1 ATOM 1983 C CA . THR A 1 269 ? 12.362 98.100 -47.948 1.00 12.62 ? 325 THR B CA 1 ATOM 1984 C C . THR A 1 269 ? 13.318 97.784 -46.775 1.00 15.04 ? 325 THR B C 1 ATOM 1985 O O . THR A 1 269 ? 13.733 96.625 -46.595 1.00 6.83 ? 325 THR B O 1 ATOM 1986 C CB . THR A 1 269 ? 10.884 98.124 -47.512 1.00 13.14 ? 325 THR B CB 1 ATOM 1987 O OG1 . THR A 1 269 ? 10.210 99.226 -48.142 1.00 12.50 ? 325 THR B OG1 1 ATOM 1988 C CG2 . THR A 1 269 ? 10.720 98.128 -46.029 1.00 2.00 ? 325 THR B CG2 1 ATOM 1989 N N . ILE A 1 270 ? 13.720 98.793 -46.005 1.00 15.62 ? 326 ILE B N 1 ATOM 1990 C CA . ILE A 1 270 ? 14.458 98.497 -44.778 1.00 10.28 ? 326 ILE B CA 1 ATOM 1991 C C . ILE A 1 270 ? 13.442 97.927 -43.783 1.00 17.00 ? 326 ILE B C 1 ATOM 1992 O O . ILE A 1 270 ? 12.475 98.602 -43.393 1.00 24.20 ? 326 ILE B O 1 ATOM 1993 C CB . ILE A 1 270 ? 15.152 99.738 -44.200 1.00 15.19 ? 326 ILE B CB 1 ATOM 1994 C CG1 . ILE A 1 270 ? 16.155 100.334 -45.203 1.00 7.65 ? 326 ILE B CG1 1 ATOM 1995 C CG2 . ILE A 1 270 ? 15.841 99.410 -42.870 1.00 9.17 ? 326 ILE B CG2 1 ATOM 1996 C CD1 . ILE A 1 270 ? 16.961 101.506 -44.607 1.00 2.95 ? 326 ILE B CD1 1 ATOM 1997 N N . PRO A 1 271 ? 13.623 96.663 -43.393 1.00 10.91 ? 327 PRO B N 1 ATOM 1998 C CA . PRO A 1 271 ? 12.544 96.009 -42.644 1.00 10.82 ? 327 PRO B CA 1 ATOM 1999 C C . PRO A 1 271 ? 12.363 96.510 -41.204 1.00 6.73 ? 327 PRO B C 1 ATOM 2000 O O . PRO A 1 271 ? 13.323 96.792 -40.486 1.00 12.78 ? 327 PRO B O 1 ATOM 2001 C CB . PRO A 1 271 ? 12.948 94.532 -42.669 1.00 2.00 ? 327 PRO B CB 1 ATOM 2002 C CG . PRO A 1 271 ? 14.417 94.541 -42.839 1.00 10.34 ? 327 PRO B CG 1 ATOM 2003 C CD . PRO A 1 271 ? 14.760 95.760 -43.641 1.00 11.51 ? 327 PRO B CD 1 ATOM 2004 N N . ARG A 1 272 ? 11.105 96.588 -40.797 1.00 8.22 ? 328 ARG B N 1 ATOM 2005 C CA . ARG A 1 272 ? 10.708 97.066 -39.480 1.00 16.29 ? 328 ARG B CA 1 ATOM 2006 C C . ARG A 1 272 ? 11.266 96.205 -38.337 1.00 16.27 ? 328 ARG B C 1 ATOM 2007 O O . ARG A 1 272 ? 11.573 96.712 -37.247 1.00 24.58 ? 328 ARG B O 1 ATOM 2008 C CB . ARG A 1 272 ? 9.179 97.155 -39.423 1.00 11.54 ? 328 ARG B CB 1 ATOM 2009 C CG . ARG A 1 272 ? 8.603 98.159 -40.421 1.00 16.31 ? 328 ARG B CG 1 ATOM 2010 C CD . ARG A 1 272 ? 7.082 98.318 -40.303 1.00 28.58 ? 328 ARG B CD 1 ATOM 2011 N NE . ARG A 1 272 ? 6.363 97.151 -40.814 1.00 42.00 ? 328 ARG B NE 1 ATOM 2012 C CZ . ARG A 1 272 ? 5.881 96.168 -40.055 1.00 47.29 ? 328 ARG B CZ 1 ATOM 2013 N NH1 . ARG A 1 272 ? 6.032 96.207 -38.732 1.00 51.44 ? 328 ARG B NH1 1 ATOM 2014 N NH2 . ARG A 1 272 ? 5.247 95.145 -40.620 1.00 39.84 ? 328 ARG B NH2 1 ATOM 2015 N N . SER A 1 273 ? 11.428 94.912 -38.605 1.00 7.22 ? 329 SER B N 1 ATOM 2016 C CA . SER A 1 273 ? 11.897 93.966 -37.597 1.00 5.13 ? 329 SER B CA 1 ATOM 2017 C C . SER A 1 273 ? 13.242 94.377 -37.030 1.00 13.83 ? 329 SER B C 1 ATOM 2018 O O . SER A 1 273 ? 13.570 94.007 -35.904 1.00 18.33 ? 329 SER B O 1 ATOM 2019 C CB . SER A 1 273 ? 11.991 92.549 -38.171 1.00 9.43 ? 329 SER B CB 1 ATOM 2020 O OG . SER A 1 273 ? 12.992 92.466 -39.184 1.00 14.88 ? 329 SER B OG 1 ATOM 2021 N N . PHE A 1 274 ? 14.010 95.146 -37.797 1.00 2.00 ? 330 PHE B N 1 ATOM 2022 C CA . PHE A 1 274 ? 15.294 95.659 -37.319 1.00 9.78 ? 330 PHE B CA 1 ATOM 2023 C C . PHE A 1 274 ? 15.208 96.367 -35.963 1.00 7.06 ? 330 PHE B C 1 ATOM 2024 O O . PHE A 1 274 ? 16.185 96.378 -35.208 1.00 12.46 ? 330 PHE B O 1 ATOM 2025 C CB . PHE A 1 274 ? 15.951 96.593 -38.344 1.00 11.75 ? 330 PHE B CB 1 ATOM 2026 C CG . PHE A 1 274 ? 16.757 95.879 -39.388 1.00 11.22 ? 330 PHE B CG 1 ATOM 2027 C CD1 . PHE A 1 274 ? 16.599 94.514 -39.599 1.00 16.58 ? 330 PHE B CD1 1 ATOM 2028 C CD2 . PHE A 1 274 ? 17.683 96.568 -40.157 1.00 13.12 ? 330 PHE B CD2 1 ATOM 2029 C CE1 . PHE A 1 274 ? 17.339 93.854 -40.581 1.00 15.39 ? 330 PHE B CE1 1 ATOM 2030 C CE2 . PHE A 1 274 ? 18.429 95.916 -41.134 1.00 7.18 ? 330 PHE B CE2 1 ATOM 2031 C CZ . PHE A 1 274 ? 18.264 94.560 -41.338 1.00 8.74 ? 330 PHE B CZ 1 ATOM 2032 N N . GLY A 1 275 ? 14.053 96.943 -35.637 1.00 8.54 ? 331 GLY B N 1 ATOM 2033 C CA . GLY A 1 275 ? 13.861 97.524 -34.309 1.00 10.32 ? 331 GLY B CA 1 ATOM 2034 C C . GLY A 1 275 ? 14.143 96.571 -33.144 1.00 9.79 ? 331 GLY B C 1 ATOM 2035 O O . GLY A 1 275 ? 14.525 96.989 -32.061 1.00 12.34 ? 331 GLY B O 1 ATOM 2036 N N . LYS A 1 276 ? 13.958 95.278 -33.370 1.00 12.70 ? 332 LYS B N 1 ATOM 2037 C CA . LYS A 1 276 ? 14.166 94.279 -32.336 1.00 10.73 ? 332 LYS B CA 1 ATOM 2038 C C . LYS A 1 276 ? 15.652 93.980 -32.109 1.00 17.83 ? 332 LYS B C 1 ATOM 2039 O O . LYS A 1 276 ? 15.996 93.199 -31.224 1.00 20.75 ? 332 LYS B O 1 ATOM 2040 C CB . LYS A 1 276 ? 13.412 92.985 -32.663 1.00 2.69 ? 332 LYS B CB 1 ATOM 2041 C CG . LYS A 1 276 ? 11.917 93.156 -32.911 1.00 12.12 ? 332 LYS B CG 1 ATOM 2042 C CD . LYS A 1 276 ? 11.225 91.811 -33.024 1.00 20.13 ? 332 LYS B CD 1 ATOM 2043 C CE . LYS A 1 276 ? 11.740 91.027 -34.217 1.00 36.32 ? 332 LYS B CE 1 ATOM 2044 N NZ . LYS A 1 276 ? 11.677 89.549 -33.997 1.00 45.77 ? 332 LYS B NZ 1 ATOM 2045 N N . LEU A 1 277 ? 16.542 94.574 -32.900 1.00 15.93 ? 333 LEU B N 1 ATOM 2046 C CA . LEU A 1 277 ? 17.946 94.240 -32.727 1.00 10.71 ? 333 LEU B CA 1 ATOM 2047 C C . LEU A 1 277 ? 18.569 95.214 -31.751 1.00 14.79 ? 333 LEU B C 1 ATOM 2048 O O . LEU A 1 277 ? 18.955 96.317 -32.112 1.00 20.11 ? 333 LEU B O 1 ATOM 2049 C CB . LEU A 1 277 ? 18.668 94.343 -34.063 1.00 6.71 ? 333 LEU B CB 1 ATOM 2050 C CG . LEU A 1 277 ? 18.150 93.404 -35.156 1.00 14.66 ? 333 LEU B CG 1 ATOM 2051 C CD1 . LEU A 1 277 ? 18.802 93.724 -36.504 1.00 4.85 ? 333 LEU B CD1 1 ATOM 2052 C CD2 . LEU A 1 277 ? 18.363 91.933 -34.758 1.00 11.76 ? 333 LEU B CD2 1 ATOM 2053 N N . GLU A 1 278 ? 18.762 94.755 -30.525 1.00 19.05 ? 334 GLU B N 1 ATOM 2054 C CA . GLU A 1 278 ? 19.122 95.649 -29.439 1.00 14.10 ? 334 GLU B CA 1 ATOM 2055 C C . GLU A 1 278 ? 20.620 95.772 -29.344 1.00 16.65 ? 334 GLU B C 1 ATOM 2056 O O . GLU A 1 278 ? 21.140 96.637 -28.649 1.00 12.45 ? 334 GLU B O 1 ATOM 2057 C CB . GLU A 1 278 ? 18.525 95.136 -28.141 1.00 17.96 ? 334 GLU B CB 1 ATOM 2058 C CG . GLU A 1 278 ? 17.014 95.341 -28.097 1.00 38.89 ? 334 GLU B CG 1 ATOM 2059 C CD . GLU A 1 278 ? 16.376 94.918 -26.787 1.00 53.64 ? 334 GLU B CD 1 ATOM 2060 O OE1 . GLU A 1 278 ? 16.754 93.844 -26.260 1.00 54.37 ? 334 GLU B OE1 1 ATOM 2061 O OE2 . GLU A 1 278 ? 15.491 95.663 -26.295 1.00 58.44 ? 334 GLU B OE2 1 ATOM 2062 N N . ASN A 1 279 ? 21.318 94.891 -30.045 1.00 14.54 ? 335 ASN B N 1 ATOM 2063 C CA . ASN A 1 279 ? 22.760 94.978 -30.105 1.00 11.74 ? 335 ASN B CA 1 ATOM 2064 C C . ASN A 1 279 ? 23.334 95.599 -31.377 1.00 14.04 ? 335 ASN B C 1 ATOM 2065 O O . ASN A 1 279 ? 24.554 95.660 -31.533 1.00 17.92 ? 335 ASN B O 1 ATOM 2066 C CB . ASN A 1 279 ? 23.406 93.638 -29.769 1.00 13.04 ? 335 ASN B CB 1 ATOM 2067 C CG . ASN A 1 279 ? 23.182 93.242 -28.315 1.00 10.89 ? 335 ASN B CG 1 ATOM 2068 O OD1 . ASN A 1 279 ? 23.732 93.858 -27.404 1.00 22.59 ? 335 ASN B OD1 1 ATOM 2069 N ND2 . ASN A 1 279 ? 22.368 92.216 -28.094 1.00 3.97 ? 335 ASN B ND2 1 ATOM 2070 N N . LEU A 1 280 ? 22.482 96.066 -32.285 1.00 9.61 ? 336 LEU B N 1 ATOM 2071 C CA . LEU A 1 280 ? 23.007 96.528 -33.571 1.00 13.01 ? 336 LEU B CA 1 ATOM 2072 C C . LEU A 1 280 ? 23.811 97.805 -33.386 1.00 14.90 ? 336 LEU B C 1 ATOM 2073 O O . LEU A 1 280 ? 23.276 98.808 -32.917 1.00 21.56 ? 336 LEU B O 1 ATOM 2074 C CB . LEU A 1 280 ? 21.860 96.818 -34.530 1.00 10.10 ? 336 LEU B CB 1 ATOM 2075 C CG . LEU A 1 280 ? 22.283 97.199 -35.952 1.00 10.37 ? 336 LEU B CG 1 ATOM 2076 C CD1 . LEU A 1 280 ? 23.038 96.054 -36.662 1.00 3.49 ? 336 LEU B CD1 1 ATOM 2077 C CD2 . LEU A 1 280 ? 21.054 97.620 -36.747 1.00 3.31 ? 336 LEU B CD2 1 ATOM 2078 N N . GLN A 1 281 ? 25.101 97.774 -33.710 1.00 8.86 ? 337 GLN B N 1 ATOM 2079 C CA . GLN A 1 281 ? 25.875 99.013 -33.669 1.00 12.00 ? 337 GLN B CA 1 ATOM 2080 C C . GLN A 1 281 ? 26.164 99.655 -35.014 1.00 12.88 ? 337 GLN B C 1 ATOM 2081 O O . GLN A 1 281 ? 26.419 100.854 -35.103 1.00 24.48 ? 337 GLN B O 1 ATOM 2082 C CB . GLN A 1 281 ? 27.197 98.762 -32.953 1.00 11.88 ? 337 GLN B CB 1 ATOM 2083 C CG . GLN A 1 281 ? 27.020 98.377 -31.500 1.00 15.63 ? 337 GLN B CG 1 ATOM 2084 C CD . GLN A 1 281 ? 28.320 97.941 -30.883 1.00 19.26 ? 337 GLN B CD 1 ATOM 2085 O OE1 . GLN A 1 281 ? 29.385 98.477 -31.210 1.00 16.51 ? 337 GLN B OE1 1 ATOM 2086 N NE2 . GLN A 1 281 ? 28.251 96.947 -29.999 1.00 22.28 ? 337 GLN B NE2 1 ATOM 2087 N N . GLU A 1 282 ? 26.109 98.849 -36.060 1.00 9.86 ? 338 GLU B N 1 ATOM 2088 C CA . GLU A 1 282 ? 26.527 99.293 -37.386 1.00 14.80 ? 338 GLU B CA 1 ATOM 2089 C C . GLU A 1 282 ? 25.654 98.678 -38.476 1.00 11.02 ? 338 GLU B C 1 ATOM 2090 O O . GLU A 1 282 ? 25.578 97.436 -38.602 1.00 9.78 ? 338 GLU B O 1 ATOM 2091 C CB . GLU A 1 282 ? 28.000 98.945 -37.596 1.00 18.53 ? 338 GLU B CB 1 ATOM 2092 C CG . GLU A 1 282 ? 28.637 99.510 -38.844 1.00 32.42 ? 338 GLU B CG 1 ATOM 2093 C CD . GLU A 1 282 ? 30.128 99.741 -38.635 1.00 48.38 ? 338 GLU B CD 1 ATOM 2094 O OE1 . GLU A 1 282 ? 30.550 99.785 -37.449 1.00 57.51 ? 338 GLU B OE1 1 ATOM 2095 O OE2 . GLU A 1 282 ? 30.867 99.879 -39.639 1.00 40.57 ? 338 GLU B OE2 1 ATOM 2096 N N . LEU A 1 283 ? 24.999 99.548 -39.245 1.00 2.00 ? 339 LEU B N 1 ATOM 2097 C CA . LEU A 1 283 ? 24.190 99.133 -40.386 1.00 15.30 ? 339 LEU B CA 1 ATOM 2098 C C . LEU A 1 283 ? 24.686 99.824 -41.671 1.00 9.12 ? 339 LEU B C 1 ATOM 2099 O O . LEU A 1 283 ? 24.538 101.035 -41.825 1.00 5.71 ? 339 LEU B O 1 ATOM 2100 C CB . LEU A 1 283 ? 22.718 99.449 -40.109 1.00 2.00 ? 339 LEU B CB 1 ATOM 2101 C CG . LEU A 1 283 ? 21.670 99.204 -41.202 1.00 8.26 ? 339 LEU B CG 1 ATOM 2102 C CD1 . LEU A 1 283 ? 21.651 97.766 -41.701 1.00 3.40 ? 339 LEU B CD1 1 ATOM 2103 C CD2 . LEU A 1 283 ? 20.291 99.583 -40.681 1.00 5.28 ? 339 LEU B CD2 1 ATOM 2104 N N . GLN A 1 284 ? 25.292 99.057 -42.574 1.00 12.96 ? 340 GLN B N 1 ATOM 2105 C CA . GLN A 1 284 ? 25.687 99.582 -43.882 1.00 11.70 ? 340 GLN B CA 1 ATOM 2106 C C . GLN A 1 284 ? 24.921 98.918 -45.016 1.00 11.93 ? 340 GLN B C 1 ATOM 2107 O O . GLN A 1 284 ? 25.097 97.734 -45.295 1.00 16.24 ? 340 GLN B O 1 ATOM 2108 C CB . GLN A 1 284 ? 27.188 99.434 -44.085 1.00 10.36 ? 340 GLN B CB 1 ATOM 2109 C CG . GLN A 1 284 ? 27.944 100.056 -42.928 1.00 13.08 ? 340 GLN B CG 1 ATOM 2110 C CD . GLN A 1 284 ? 29.353 100.451 -43.269 1.00 22.65 ? 340 GLN B CD 1 ATOM 2111 O OE1 . GLN A 1 284 ? 29.943 101.278 -42.583 1.00 38.87 ? 340 GLN B OE1 1 ATOM 2112 N NE2 . GLN A 1 284 ? 29.910 99.858 -44.318 1.00 22.62 ? 340 GLN B NE2 1 ATOM 2113 N N . LEU A 1 285 ? 24.000 99.688 -45.584 1.00 14.30 ? 341 LEU B N 1 ATOM 2114 C CA . LEU A 1 285 ? 23.244 99.365 -46.795 1.00 4.55 ? 341 LEU B CA 1 ATOM 2115 C C . LEU A 1 285 ? 23.668 100.132 -48.047 1.00 6.44 ? 341 LEU B C 1 ATOM 2116 O O . LEU A 1 285 ? 22.965 100.118 -49.046 1.00 13.25 ? 341 LEU B O 1 ATOM 2117 C CB . LEU A 1 285 ? 21.747 99.490 -46.536 1.00 2.00 ? 341 LEU B CB 1 ATOM 2118 C CG . LEU A 1 285 ? 21.336 98.639 -45.321 1.00 2.93 ? 341 LEU B CG 1 ATOM 2119 C CD1 . LEU A 1 285 ? 19.842 98.763 -45.034 1.00 2.00 ? 341 LEU B CD1 1 ATOM 2120 C CD2 . LEU A 1 285 ? 21.730 97.170 -45.512 1.00 2.00 ? 341 LEU B CD2 1 ATOM 2121 N N . SER A 1 286 ? 24.773 100.864 -47.978 1.00 11.01 ? 342 SER B N 1 ATOM 2122 C CA . SER A 1 286 ? 25.185 101.751 -49.078 1.00 11.24 ? 342 SER B CA 1 ATOM 2123 C C . SER A 1 286 ? 25.234 101.114 -50.479 1.00 12.36 ? 342 SER B C 1 ATOM 2124 O O . SER A 1 286 ? 25.610 99.955 -50.632 1.00 8.55 ? 342 SER B O 1 ATOM 2125 C CB . SER A 1 286 ? 26.560 102.321 -48.765 1.00 5.06 ? 342 SER B CB 1 ATOM 2126 O OG . SER A 1 286 ? 26.543 102.965 -47.512 1.00 7.35 ? 342 SER B OG 1 ATOM 2127 N N . VAL A 1 287 ? 24.867 101.890 -51.499 1.00 15.09 ? 343 VAL B N 1 ATOM 2128 C CA . VAL A 1 287 ? 24.897 101.439 -52.905 1.00 2.35 ? 343 VAL B CA 1 ATOM 2129 C C . VAL A 1 287 ? 24.047 100.196 -53.177 1.00 2.00 ? 343 VAL B C 1 ATOM 2130 O O . VAL A 1 287 ? 24.551 99.103 -53.370 1.00 13.38 ? 343 VAL B O 1 ATOM 2131 C CB . VAL A 1 287 ? 26.322 101.219 -53.431 1.00 8.47 ? 343 VAL B CB 1 ATOM 2132 C CG1 . VAL A 1 287 ? 26.330 101.285 -54.971 1.00 2.00 ? 343 VAL B CG1 1 ATOM 2133 C CG2 . VAL A 1 287 ? 27.287 102.267 -52.832 1.00 2.00 ? 343 VAL B CG2 1 ATOM 2134 N N . ASN A 1 288 ? 22.742 100.387 -53.124 1.00 3.31 ? 344 ASN B N 1 ATOM 2135 C CA . ASN A 1 288 ? 21.769 99.379 -53.465 1.00 3.77 ? 344 ASN B CA 1 ATOM 2136 C C . ASN A 1 288 ? 20.559 100.069 -54.089 1.00 10.91 ? 344 ASN B C 1 ATOM 2137 O O . ASN A 1 288 ? 20.632 101.208 -54.521 1.00 15.38 ? 344 ASN B O 1 ATOM 2138 C CB . ASN A 1 288 ? 21.325 98.591 -52.236 1.00 9.68 ? 344 ASN B CB 1 ATOM 2139 C CG . ASN A 1 288 ? 22.311 97.509 -51.838 1.00 15.12 ? 344 ASN B CG 1 ATOM 2140 O OD1 . ASN A 1 288 ? 22.354 96.439 -52.450 1.00 10.44 ? 344 ASN B OD1 1 ATOM 2141 N ND2 . ASN A 1 288 ? 23.091 97.771 -50.787 1.00 6.25 ? 344 ASN B ND2 1 ATOM 2142 N N . GLN A 1 289 ? 19.495 99.307 -54.252 1.00 10.30 ? 345 GLN B N 1 ATOM 2143 C CA . GLN A 1 289 ? 18.212 99.778 -54.754 1.00 14.24 ? 345 GLN B CA 1 ATOM 2144 C C . GLN A 1 289 ? 17.076 99.872 -53.754 1.00 15.63 ? 345 GLN B C 1 ATOM 2145 O O . GLN A 1 289 ? 15.916 99.693 -54.147 1.00 9.11 ? 345 GLN B O 1 ATOM 2146 C CB . GLN A 1 289 ? 17.806 99.092 -56.044 1.00 10.40 ? 345 GLN B CB 1 ATOM 2147 C CG . GLN A 1 289 ? 18.655 99.543 -57.209 1.00 15.54 ? 345 GLN B CG 1 ATOM 2148 C CD . GLN A 1 289 ? 18.721 98.480 -58.277 1.00 31.20 ? 345 GLN B CD 1 ATOM 2149 O OE1 . GLN A 1 289 ? 17.687 98.018 -58.768 1.00 33.99 ? 345 GLN B OE1 1 ATOM 2150 N NE2 . GLN A 1 289 ? 19.938 98.054 -58.620 1.00 38.28 ? 345 GLN B NE2 1 ATOM 2151 N N . ILE A 1 290 ? 17.415 99.911 -52.469 1.00 12.07 ? 346 ILE B N 1 ATOM 2152 C CA . ILE A 1 290 ? 16.410 99.927 -51.412 1.00 12.87 ? 346 ILE B CA 1 ATOM 2153 C C . ILE A 1 290 ? 15.396 101.089 -51.505 1.00 14.12 ? 346 ILE B C 1 ATOM 2154 O O . ILE A 1 290 ? 15.761 102.275 -51.531 1.00 7.86 ? 346 ILE B O 1 ATOM 2155 C CB . ILE A 1 290 ? 17.090 99.907 -50.032 1.00 6.20 ? 346 ILE B CB 1 ATOM 2156 C CG1 . ILE A 1 290 ? 17.929 98.638 -49.905 1.00 9.80 ? 346 ILE B CG1 1 ATOM 2157 C CG2 . ILE A 1 290 ? 16.046 99.975 -48.920 1.00 4.07 ? 346 ILE B CG2 1 ATOM 2158 C CD1 . ILE A 1 290 ? 18.730 98.544 -48.620 1.00 19.69 ? 346 ILE B CD1 1 ATOM 2159 N N . SER A 1 291 ? 14.117 100.733 -51.569 1.00 10.96 ? 347 SER B N 1 ATOM 2160 C CA . SER A 1 291 ? 13.040 101.724 -51.628 1.00 14.73 ? 347 SER B CA 1 ATOM 2161 C C . SER A 1 291 ? 12.407 101.890 -50.253 1.00 16.22 ? 347 SER B C 1 ATOM 2162 O O . SER A 1 291 ? 12.939 101.399 -49.258 1.00 23.21 ? 347 SER B O 1 ATOM 2163 C CB . SER A 1 291 ? 11.993 101.368 -52.699 1.00 2.00 ? 347 SER B CB 1 ATOM 2164 O OG . SER A 1 291 ? 11.719 99.977 -52.692 1.00 19.00 ? 347 SER B OG 1 ATOM 2165 N N . GLY A 1 292 ? 11.288 102.604 -50.204 1.00 11.44 ? 348 GLY B N 1 ATOM 2166 C CA . GLY A 1 292 ? 10.552 102.790 -48.969 1.00 5.37 ? 348 GLY B CA 1 ATOM 2167 C C . GLY A 1 292 ? 11.099 103.954 -48.164 1.00 12.01 ? 348 GLY B C 1 ATOM 2168 O O . GLY A 1 292 ? 11.927 104.722 -48.656 1.00 20.54 ? 348 GLY B O 1 ATOM 2169 N N . THR A 1 293 ? 10.646 104.073 -46.918 1.00 5.11 ? 349 THR B N 1 ATOM 2170 C CA . THR A 1 293 ? 11.139 105.096 -45.999 1.00 8.09 ? 349 THR B CA 1 ATOM 2171 C C . THR A 1 293 ? 11.884 104.454 -44.823 1.00 10.54 ? 349 THR B C 1 ATOM 2172 O O . THR A 1 293 ? 11.663 103.292 -44.507 1.00 17.76 ? 349 THR B O 1 ATOM 2173 C CB . THR A 1 293 ? 9.973 105.892 -45.403 1.00 6.16 ? 349 THR B CB 1 ATOM 2174 O OG1 . THR A 1 293 ? 9.285 105.064 -44.462 1.00 15.04 ? 349 THR B OG1 1 ATOM 2175 C CG2 . THR A 1 293 ? 8.997 106.339 -46.494 1.00 2.03 ? 349 THR B CG2 1 ATOM 2176 N N . ILE A 1 294 ? 12.755 105.216 -44.172 1.00 11.52 ? 350 ILE B N 1 ATOM 2177 C CA . ILE A 1 294 ? 13.450 104.734 -42.977 1.00 14.25 ? 350 ILE B CA 1 ATOM 2178 C C . ILE A 1 294 ? 12.423 104.433 -41.891 1.00 11.06 ? 350 ILE B C 1 ATOM 2179 O O . ILE A 1 294 ? 11.729 105.330 -41.423 1.00 14.18 ? 350 ILE B O 1 ATOM 2180 C CB . ILE A 1 294 ? 14.432 105.791 -42.445 1.00 12.54 ? 350 ILE B CB 1 ATOM 2181 C CG1 . ILE A 1 294 ? 15.315 106.307 -43.590 1.00 2.78 ? 350 ILE B CG1 1 ATOM 2182 C CG2 . ILE A 1 294 ? 15.257 105.225 -41.290 1.00 7.76 ? 350 ILE B CG2 1 ATOM 2183 C CD1 . ILE A 1 294 ? 15.986 107.606 -43.309 1.00 2.00 ? 350 ILE B CD1 1 ATOM 2184 N N . PRO A 1 295 ? 12.290 103.154 -41.516 1.00 6.32 ? 351 PRO B N 1 ATOM 2185 C CA . PRO A 1 295 ? 11.209 102.853 -40.582 1.00 8.19 ? 351 PRO B CA 1 ATOM 2186 C C . PRO A 1 295 ? 11.498 103.418 -39.194 1.00 9.87 ? 351 PRO B C 1 ATOM 2187 O O . PRO A 1 295 ? 12.618 103.298 -38.719 1.00 12.85 ? 351 PRO B O 1 ATOM 2188 C CB . PRO A 1 295 ? 11.178 101.321 -40.570 1.00 3.65 ? 351 PRO B CB 1 ATOM 2189 C CG . PRO A 1 295 ? 12.533 100.901 -41.059 1.00 4.39 ? 351 PRO B CG 1 ATOM 2190 C CD . PRO A 1 295 ? 12.933 101.936 -42.039 1.00 2.00 ? 351 PRO B CD 1 ATOM 2191 N N . GLU A 1 296 ? 10.503 104.032 -38.564 1.00 12.93 ? 352 GLU B N 1 ATOM 2192 C CA . GLU A 1 296 ? 10.665 104.554 -37.206 1.00 21.55 ? 352 GLU B CA 1 ATOM 2193 C C . GLU A 1 296 ? 11.157 103.526 -36.191 1.00 17.62 ? 352 GLU B C 1 ATOM 2194 O O . GLU A 1 296 ? 11.904 103.876 -35.281 1.00 11.24 ? 352 GLU B O 1 ATOM 2195 C CB . GLU A 1 296 ? 9.395 105.242 -36.708 1.00 27.17 ? 352 GLU B CB 1 ATOM 2196 C CG . GLU A 1 296 ? 9.191 106.624 -37.326 1.00 42.22 ? 352 GLU B CG 1 ATOM 2197 C CD . GLU A 1 296 ? 8.775 107.657 -36.305 1.00 56.30 ? 352 GLU B CD 1 ATOM 2198 O OE1 . GLU A 1 296 ? 9.526 108.649 -36.117 1.00 59.99 ? 352 GLU B OE1 1 ATOM 2199 O OE2 . GLU A 1 296 ? 7.698 107.469 -35.692 1.00 59.43 ? 352 GLU B OE2 1 ATOM 2200 N N . GLU A 1 297 ? 10.792 102.258 -36.358 1.00 14.58 ? 353 GLU B N 1 ATOM 2201 C CA . GLU A 1 297 ? 11.274 101.258 -35.412 1.00 14.71 ? 353 GLU B CA 1 ATOM 2202 C C . GLU A 1 297 ? 12.796 101.100 -35.378 1.00 8.81 ? 353 GLU B C 1 ATOM 2203 O O . GLU A 1 297 ? 13.335 100.615 -34.388 1.00 17.17 ? 353 GLU B O 1 ATOM 2204 C CB . GLU A 1 297 ? 10.545 99.910 -35.529 1.00 15.16 ? 353 GLU B CB 1 ATOM 2205 C CG . GLU A 1 297 ? 10.032 99.583 -36.890 1.00 30.19 ? 353 GLU B CG 1 ATOM 2206 C CD . GLU A 1 297 ? 8.722 100.262 -37.192 1.00 30.68 ? 353 GLU B CD 1 ATOM 2207 O OE1 . GLU A 1 297 ? 7.700 99.878 -36.584 1.00 27.44 ? 353 GLU B OE1 1 ATOM 2208 O OE2 . GLU A 1 297 ? 8.724 101.180 -38.040 1.00 34.73 ? 353 GLU B OE2 1 ATOM 2209 N N . LEU A 1 298 ? 13.487 101.548 -36.427 1.00 11.66 ? 354 LEU B N 1 ATOM 2210 C CA . LEU A 1 298 ? 14.963 101.543 -36.462 1.00 10.88 ? 354 LEU B CA 1 ATOM 2211 C C . LEU A 1 298 ? 15.513 102.458 -35.378 1.00 16.12 ? 354 LEU B C 1 ATOM 2212 O O . LEU A 1 298 ? 16.652 102.293 -34.930 1.00 12.86 ? 354 LEU B O 1 ATOM 2213 C CB . LEU A 1 298 ? 15.500 102.046 -37.811 1.00 7.72 ? 354 LEU B CB 1 ATOM 2214 C CG . LEU A 1 298 ? 16.665 101.326 -38.513 1.00 14.68 ? 354 LEU B CG 1 ATOM 2215 C CD1 . LEU A 1 298 ? 17.516 102.281 -39.321 1.00 7.54 ? 354 LEU B CD1 1 ATOM 2216 C CD2 . LEU A 1 298 ? 17.541 100.550 -37.571 1.00 21.53 ? 354 LEU B CD2 1 ATOM 2217 N N . THR A 1 299 ? 14.724 103.455 -34.984 1.00 10.43 ? 355 THR B N 1 ATOM 2218 C CA . THR A 1 299 ? 15.157 104.336 -33.914 1.00 17.38 ? 355 THR B CA 1 ATOM 2219 C C . THR A 1 299 ? 15.110 103.646 -32.557 1.00 11.21 ? 355 THR B C 1 ATOM 2220 O O . THR A 1 299 ? 15.561 104.209 -31.579 1.00 5.66 ? 355 THR B O 1 ATOM 2221 C CB . THR A 1 299 ? 14.329 105.612 -33.829 1.00 21.22 ? 355 THR B CB 1 ATOM 2222 O OG1 . THR A 1 299 ? 13.055 105.309 -33.246 1.00 17.80 ? 355 THR B OG1 1 ATOM 2223 C CG2 . THR A 1 299 ? 14.183 106.255 -35.217 1.00 12.82 ? 355 THR B CG2 1 ATOM 2224 N N . ASN A 1 300 ? 14.569 102.433 -32.498 1.00 8.26 ? 356 ASN B N 1 ATOM 2225 C CA . ASN A 1 300 ? 14.645 101.634 -31.278 1.00 12.18 ? 356 ASN B CA 1 ATOM 2226 C C . ASN A 1 300 ? 16.023 100.981 -31.066 1.00 17.50 ? 356 ASN B C 1 ATOM 2227 O O . ASN A 1 300 ? 16.267 100.396 -30.005 1.00 18.72 ? 356 ASN B O 1 ATOM 2228 C CB . ASN A 1 300 ? 13.570 100.542 -31.272 1.00 20.35 ? 356 ASN B CB 1 ATOM 2229 C CG . ASN A 1 300 ? 12.698 100.587 -30.045 1.00 29.30 ? 356 ASN B CG 1 ATOM 2230 O OD1 . ASN A 1 300 ? 12.246 101.656 -29.628 1.00 31.30 ? 356 ASN B OD1 1 ATOM 2231 N ND2 . ASN A 1 300 ? 12.451 99.417 -29.453 1.00 36.86 ? 356 ASN B ND2 1 ATOM 2232 N N . CYS A 1 301 ? 16.936 101.088 -32.040 1.00 13.61 ? 357 CYS B N 1 ATOM 2233 C CA . CYS A 1 301 ? 18.204 100.383 -31.894 1.00 13.09 ? 357 CYS B CA 1 ATOM 2234 C C . CYS A 1 301 ? 19.157 101.306 -31.150 1.00 20.68 ? 357 CYS B C 1 ATOM 2235 O O . CYS A 1 301 ? 19.890 102.106 -31.741 1.00 11.70 ? 357 CYS B O 1 ATOM 2236 C CB . CYS A 1 301 ? 18.791 100.071 -33.270 1.00 12.44 ? 357 CYS B CB 1 ATOM 2237 S SG . CYS A 1 301 ? 17.812 98.963 -34.348 1.00 20.34 ? 357 CYS B SG 1 ATOM 2238 N N . THR A 1 302 ? 19.249 101.054 -29.853 1.00 22.34 ? 358 THR B N 1 ATOM 2239 C CA . THR A 1 302 ? 19.748 102.028 -28.895 1.00 16.89 ? 358 THR B CA 1 ATOM 2240 C C . THR A 1 302 ? 21.242 102.217 -29.077 1.00 13.49 ? 358 THR B C 1 ATOM 2241 O O . THR A 1 302 ? 21.799 103.272 -28.774 1.00 17.96 ? 358 THR B O 1 ATOM 2242 C CB . THR A 1 302 ? 19.395 101.557 -27.449 1.00 22.73 ? 358 THR B CB 1 ATOM 2243 O OG1 . THR A 1 302 ? 18.122 102.100 -27.069 1.00 26.70 ? 358 THR B OG1 1 ATOM 2244 C CG2 . THR A 1 302 ? 20.435 101.977 -26.441 1.00 16.16 ? 358 THR B CG2 1 ATOM 2245 N N . LYS A 1 303 ? 21.882 101.184 -29.609 1.00 16.20 ? 359 LYS B N 1 ATOM 2246 C CA . LYS A 1 303 ? 23.330 101.155 -29.669 1.00 11.69 ? 359 LYS B CA 1 ATOM 2247 C C . LYS A 1 303 ? 23.947 101.580 -30.997 1.00 7.65 ? 359 LYS B C 1 ATOM 2248 O O . LYS A 1 303 ? 25.168 101.540 -31.130 1.00 13.44 ? 359 LYS B O 1 ATOM 2249 C CB . LYS A 1 303 ? 23.849 99.782 -29.241 1.00 15.55 ? 359 LYS B CB 1 ATOM 2250 C CG . LYS A 1 303 ? 23.408 99.400 -27.838 1.00 22.21 ? 359 LYS B CG 1 ATOM 2251 C CD . LYS A 1 303 ? 24.430 98.519 -27.139 1.00 28.02 ? 359 LYS B CD 1 ATOM 2252 C CE . LYS A 1 303 ? 24.108 97.040 -27.294 1.00 35.15 ? 359 LYS B CE 1 ATOM 2253 N NZ . LYS A 1 303 ? 25.094 96.180 -26.564 1.00 35.86 ? 359 LYS B NZ 1 ATOM 2254 N N . LEU A 1 304 ? 23.134 101.997 -31.967 1.00 4.12 ? 360 LEU B N 1 ATOM 2255 C CA . LEU A 1 304 ? 23.673 102.310 -33.287 1.00 2.19 ? 360 LEU B CA 1 ATOM 2256 C C . LEU A 1 304 ? 24.692 103.428 -33.195 1.00 8.72 ? 360 LEU B C 1 ATOM 2257 O O . LEU A 1 304 ? 24.370 104.536 -32.759 1.00 15.05 ? 360 LEU B O 1 ATOM 2258 C CB . LEU A 1 304 ? 22.532 102.794 -34.165 1.00 7.38 ? 360 LEU B CB 1 ATOM 2259 C CG . LEU A 1 304 ? 22.483 102.399 -35.634 1.00 11.37 ? 360 LEU B CG 1 ATOM 2260 C CD1 . LEU A 1 304 ? 22.776 100.912 -35.808 1.00 6.76 ? 360 LEU B CD1 1 ATOM 2261 C CD2 . LEU A 1 304 ? 21.098 102.730 -36.148 1.00 11.85 ? 360 LEU B CD2 1 ATOM 2262 N N . THR A 1 305 ? 25.934 103.135 -33.572 1.00 8.29 ? 361 THR B N 1 ATOM 2263 C CA . THR A 1 305 ? 26.910 104.182 -33.875 1.00 7.89 ? 361 THR B CA 1 ATOM 2264 C C . THR A 1 305 ? 26.953 104.616 -35.352 1.00 6.51 ? 361 THR B C 1 ATOM 2265 O O . THR A 1 305 ? 27.019 105.808 -35.645 1.00 12.69 ? 361 THR B O 1 ATOM 2266 C CB . THR A 1 305 ? 28.316 103.847 -33.332 1.00 11.56 ? 361 THR B CB 1 ATOM 2267 O OG1 . THR A 1 305 ? 28.872 102.752 -34.068 1.00 20.29 ? 361 THR B OG1 1 ATOM 2268 C CG2 . THR A 1 305 ? 28.221 103.454 -31.869 1.00 4.06 ? 361 THR B CG2 1 ATOM 2269 N N . HIS A 1 306 ? 26.914 103.649 -36.273 1.00 6.56 ? 362 HIS B N 1 ATOM 2270 C CA . HIS A 1 306 ? 27.059 103.930 -37.723 1.00 9.21 ? 362 HIS B CA 1 ATOM 2271 C C . HIS A 1 306 ? 25.835 103.539 -38.547 1.00 12.43 ? 362 HIS B C 1 ATOM 2272 O O . HIS A 1 306 ? 25.475 102.355 -38.623 1.00 7.52 ? 362 HIS B O 1 ATOM 2273 C CB . HIS A 1 306 ? 28.265 103.205 -38.332 1.00 3.08 ? 362 HIS B CB 1 ATOM 2274 C CG . HIS A 1 306 ? 29.591 103.660 -37.803 1.00 18.43 ? 362 HIS B CG 1 ATOM 2275 N ND1 . HIS A 1 306 ? 29.942 103.556 -36.474 1.00 28.66 ? 362 HIS B ND1 1 ATOM 2276 C CD2 . HIS A 1 306 ? 30.659 104.204 -38.430 1.00 29.52 ? 362 HIS B CD2 1 ATOM 2277 C CE1 . HIS A 1 306 ? 31.165 104.023 -36.302 1.00 24.67 ? 362 HIS B CE1 1 ATOM 2278 N NE2 . HIS A 1 306 ? 31.623 104.420 -37.475 1.00 31.09 ? 362 HIS B NE2 1 ATOM 2279 N N . LEU A 1 307 ? 25.200 104.532 -39.169 1.00 12.38 ? 363 LEU B N 1 ATOM 2280 C CA . LEU A 1 307 ? 24.110 104.260 -40.104 1.00 9.37 ? 363 LEU B CA 1 ATOM 2281 C C . LEU A 1 307 ? 24.415 104.798 -41.514 1.00 11.63 ? 363 LEU B C 1 ATOM 2282 O O . LEU A 1 307 ? 24.362 106.019 -41.759 1.00 9.76 ? 363 LEU B O 1 ATOM 2283 C CB . LEU A 1 307 ? 22.808 104.859 -39.576 1.00 2.12 ? 363 LEU B CB 1 ATOM 2284 C CG . LEU A 1 307 ? 21.578 104.591 -40.441 1.00 11.11 ? 363 LEU B CG 1 ATOM 2285 C CD1 . LEU A 1 307 ? 21.276 103.096 -40.475 1.00 6.74 ? 363 LEU B CD1 1 ATOM 2286 C CD2 . LEU A 1 307 ? 20.373 105.385 -39.943 1.00 4.27 ? 363 LEU B CD2 1 ATOM 2287 N N . GLU A 1 308 ? 24.708 103.886 -42.446 1.00 10.30 ? 364 GLU B N 1 ATOM 2288 C CA . GLU A 1 308 ? 24.971 104.295 -43.824 1.00 10.31 ? 364 GLU B CA 1 ATOM 2289 C C . GLU A 1 308 ? 24.013 103.654 -44.801 1.00 15.97 ? 364 GLU B C 1 ATOM 2290 O O . GLU A 1 308 ? 24.120 102.460 -45.116 1.00 16.10 ? 364 GLU B O 1 ATOM 2291 C CB . GLU A 1 308 ? 26.397 103.955 -44.212 1.00 11.46 ? 364 GLU B CB 1 ATOM 2292 C CG . GLU A 1 308 ? 27.391 104.980 -43.705 1.00 22.87 ? 364 GLU B CG 1 ATOM 2293 C CD . GLU A 1 308 ? 28.394 104.367 -42.789 1.00 33.87 ? 364 GLU B CD 1 ATOM 2294 O OE1 . GLU A 1 308 ? 29.404 103.852 -43.315 1.00 41.87 ? 364 GLU B OE1 1 ATOM 2295 O OE2 . GLU A 1 308 ? 28.159 104.383 -41.558 1.00 32.88 ? 364 GLU B OE2 1 ATOM 2296 N N . ILE A 1 309 ? 23.057 104.475 -45.232 1.00 6.78 ? 365 ILE B N 1 ATOM 2297 C CA . ILE A 1 309 ? 22.043 104.139 -46.214 1.00 4.67 ? 365 ILE B CA 1 ATOM 2298 C C . ILE A 1 309 ? 22.155 104.842 -47.557 1.00 10.06 ? 365 ILE B C 1 ATOM 2299 O O . ILE A 1 309 ? 21.176 104.923 -48.298 1.00 13.52 ? 365 ILE B O 1 ATOM 2300 C CB . ILE A 1 309 ? 20.623 104.181 -45.650 1.00 10.30 ? 365 ILE B CB 1 ATOM 2301 C CG1 . ILE A 1 309 ? 20.301 105.566 -45.091 1.00 3.59 ? 365 ILE B CG1 1 ATOM 2302 C CG2 . ILE A 1 309 ? 20.438 103.054 -44.627 1.00 2.00 ? 365 ILE B CG2 1 ATOM 2303 C CD1 . ILE A 1 309 ? 18.891 105.665 -44.557 1.00 2.00 ? 365 ILE B CD1 1 ATOM 2304 N N . ASP A 1 310 ? 23.292 105.475 -47.796 1.00 6.81 ? 366 ASP B N 1 ATOM 2305 C CA . ASP A 1 310 ? 23.486 106.302 -48.986 1.00 10.09 ? 366 ASP B CA 1 ATOM 2306 C C . ASP A 1 310 ? 23.368 105.512 -50.321 1.00 13.27 ? 366 ASP B C 1 ATOM 2307 O O . ASP A 1 310 ? 23.410 104.283 -50.332 1.00 2.00 ? 366 ASP B O 1 ATOM 2308 C CB . ASP A 1 310 ? 24.843 107.007 -48.889 1.00 5.40 ? 366 ASP B CB 1 ATOM 2309 C CG . ASP A 1 310 ? 26.004 106.021 -48.820 1.00 16.05 ? 366 ASP B CG 1 ATOM 2310 O OD1 . ASP A 1 310 ? 26.239 105.427 -47.732 1.00 17.78 ? 366 ASP B OD1 1 ATOM 2311 O OD2 . ASP A 1 310 ? 26.675 105.832 -49.863 1.00 22.22 ? 366 ASP B OD2 1 ATOM 2312 N N . ASN A 1 311 ? 23.147 106.228 -51.425 1.00 7.18 ? 367 ASN B N 1 ATOM 2313 C CA . ASN A 1 311 ? 23.047 105.620 -52.759 1.00 2.00 ? 367 ASN B CA 1 ATOM 2314 C C . ASN A 1 311 ? 21.996 104.512 -52.864 1.00 4.70 ? 367 ASN B C 1 ATOM 2315 O O . ASN A 1 311 ? 22.310 103.347 -53.140 1.00 2.00 ? 367 ASN B O 1 ATOM 2316 C CB . ASN A 1 311 ? 24.419 105.117 -53.237 1.00 3.47 ? 367 ASN B CB 1 ATOM 2317 C CG . ASN A 1 311 ? 25.367 106.256 -53.589 1.00 8.14 ? 367 ASN B CG 1 ATOM 2318 O OD1 . ASN A 1 311 ? 25.288 106.818 -54.674 1.00 18.69 ? 367 ASN B OD1 1 ATOM 2319 N ND2 . ASN A 1 311 ? 26.256 106.610 -52.663 1.00 2.87 ? 367 ASN B ND2 1 ATOM 2320 N N . ASN A 1 312 ? 20.745 104.907 -52.654 1.00 2.74 ? 368 ASN B N 1 ATOM 2321 C CA . ASN A 1 312 ? 19.591 104.008 -52.707 1.00 3.83 ? 368 ASN B CA 1 ATOM 2322 C C . ASN A 1 312 ? 18.361 104.741 -53.264 1.00 10.18 ? 368 ASN B C 1 ATOM 2323 O O . ASN A 1 312 ? 18.469 105.806 -53.859 1.00 6.76 ? 368 ASN B O 1 ATOM 2324 C CB . ASN A 1 312 ? 19.276 103.468 -51.313 1.00 8.52 ? 368 ASN B CB 1 ATOM 2325 C CG . ASN A 1 312 ? 20.243 102.369 -50.870 1.00 16.59 ? 368 ASN B CG 1 ATOM 2326 O OD1 . ASN A 1 312 ? 20.131 101.228 -51.315 1.00 12.88 ? 368 ASN B OD1 1 ATOM 2327 N ND2 . ASN A 1 312 ? 21.185 102.707 -49.967 1.00 10.47 ? 368 ASN B ND2 1 ATOM 2328 N N . LEU A 1 313 ? 17.202 104.120 -53.140 1.00 14.27 ? 369 LEU B N 1 ATOM 2329 C CA . LEU A 1 313 ? 15.932 104.733 -53.529 1.00 14.09 ? 369 LEU B CA 1 ATOM 2330 C C . LEU A 1 313 ? 15.047 105.259 -52.381 1.00 15.60 ? 369 LEU B C 1 ATOM 2331 O O . LEU A 1 313 ? 13.845 105.419 -52.573 1.00 8.20 ? 369 LEU B O 1 ATOM 2332 C CB . LEU A 1 313 ? 15.170 103.847 -54.526 1.00 17.90 ? 369 LEU B CB 1 ATOM 2333 C CG . LEU A 1 313 ? 15.984 103.454 -55.782 1.00 21.33 ? 369 LEU B CG 1 ATOM 2334 C CD1 . LEU A 1 313 ? 15.252 102.419 -56.653 1.00 10.97 ? 369 LEU B CD1 1 ATOM 2335 C CD2 . LEU A 1 313 ? 16.386 104.667 -56.615 1.00 2.00 ? 369 LEU B CD2 1 ATOM 2336 N N . ILE A 1 314 ? 15.583 105.376 -51.163 1.00 22.18 ? 370 ILE B N 1 ATOM 2337 C CA . ILE A 1 314 ? 14.767 105.797 -50.008 1.00 11.77 ? 370 ILE B CA 1 ATOM 2338 C C . ILE A 1 314 ? 14.018 107.131 -50.198 1.00 10.84 ? 370 ILE B C 1 ATOM 2339 O O . ILE A 1 314 ? 14.574 108.107 -50.700 1.00 14.09 ? 370 ILE B O 1 ATOM 2340 C CB . ILE A 1 314 ? 15.586 105.918 -48.722 1.00 13.63 ? 370 ILE B CB 1 ATOM 2341 C CG1 . ILE A 1 314 ? 16.633 104.811 -48.604 1.00 13.98 ? 370 ILE B CG1 1 ATOM 2342 C CG2 . ILE A 1 314 ? 14.661 105.903 -47.500 1.00 18.33 ? 370 ILE B CG2 1 ATOM 2343 C CD1 . ILE A 1 314 ? 16.076 103.490 -48.384 1.00 5.31 ? 370 ILE B CD1 1 ATOM 2344 N N . THR A 1 315 ? 12.757 107.163 -49.776 1.00 6.72 ? 371 THR B N 1 ATOM 2345 C CA . THR A 1 315 ? 11.914 108.349 -49.862 1.00 7.65 ? 371 THR B CA 1 ATOM 2346 C C . THR A 1 315 ? 11.371 108.665 -48.469 1.00 15.75 ? 371 THR B C 1 ATOM 2347 O O . THR A 1 315 ? 11.622 107.923 -47.520 1.00 21.13 ? 371 THR B O 1 ATOM 2348 C CB . THR A 1 315 ? 10.699 108.066 -50.757 1.00 9.34 ? 371 THR B CB 1 ATOM 2349 O OG1 . THR A 1 315 ? 10.049 106.885 -50.284 1.00 12.75 ? 371 THR B OG1 1 ATOM 2350 C CG2 . THR A 1 315 ? 11.114 107.820 -52.226 1.00 5.41 ? 371 THR B CG2 1 ATOM 2351 N N . GLY A 1 316 ? 10.602 109.750 -48.359 1.00 16.29 ? 372 GLY B N 1 ATOM 2352 C CA . GLY A 1 316 ? 9.957 110.129 -47.123 1.00 2.00 ? 372 GLY B CA 1 ATOM 2353 C C . GLY A 1 316 ? 10.840 111.045 -46.323 1.00 12.87 ? 372 GLY B C 1 ATOM 2354 O O . GLY A 1 316 ? 11.839 111.558 -46.846 1.00 9.68 ? 372 GLY B O 1 ATOM 2355 N N . GLU A 1 317 ? 10.495 111.222 -45.044 1.00 5.34 ? 373 GLU B N 1 ATOM 2356 C CA . GLU A 1 317 ? 11.200 112.140 -44.161 1.00 6.78 ? 373 GLU B CA 1 ATOM 2357 C C . GLU A 1 317 ? 12.139 111.392 -43.236 1.00 15.08 ? 373 GLU B C 1 ATOM 2358 O O . GLU A 1 317 ? 11.913 110.221 -42.916 1.00 15.09 ? 373 GLU B O 1 ATOM 2359 C CB . GLU A 1 317 ? 10.226 112.943 -43.311 1.00 6.69 ? 373 GLU B CB 1 ATOM 2360 C CG . GLU A 1 317 ? 9.260 113.770 -44.128 1.00 18.77 ? 373 GLU B CG 1 ATOM 2361 C CD . GLU A 1 317 ? 8.662 114.898 -43.321 1.00 26.23 ? 373 GLU B CD 1 ATOM 2362 O OE1 . GLU A 1 317 ? 7.580 115.395 -43.692 1.00 26.35 ? 373 GLU B OE1 1 ATOM 2363 O OE2 . GLU A 1 317 ? 9.291 115.301 -42.321 1.00 35.85 ? 373 GLU B OE2 1 ATOM 2364 N N . ILE A 1 318 ? 13.225 112.058 -42.853 1.00 13.37 ? 374 ILE B N 1 ATOM 2365 C CA . ILE A 1 318 ? 14.090 111.546 -41.807 1.00 12.34 ? 374 ILE B CA 1 ATOM 2366 C C . ILE A 1 318 ? 13.293 111.689 -40.530 1.00 10.81 ? 374 ILE B C 1 ATOM 2367 O O . ILE A 1 318 ? 12.843 112.786 -40.216 1.00 12.63 ? 374 ILE B O 1 ATOM 2368 C CB . ILE A 1 318 ? 15.364 112.367 -41.697 1.00 6.33 ? 374 ILE B CB 1 ATOM 2369 C CG1 . ILE A 1 318 ? 16.204 112.200 -42.963 1.00 2.00 ? 374 ILE B CG1 1 ATOM 2370 C CG2 . ILE A 1 318 ? 16.155 111.970 -40.446 1.00 7.18 ? 374 ILE B CG2 1 ATOM 2371 C CD1 . ILE A 1 318 ? 17.229 113.302 -43.148 1.00 12.24 ? 374 ILE B CD1 1 ATOM 2372 N N . PRO A 1 319 ? 13.092 110.578 -39.804 1.00 6.84 ? 375 PRO B N 1 ATOM 2373 C CA . PRO A 1 319 ? 12.230 110.594 -38.620 1.00 9.90 ? 375 PRO B CA 1 ATOM 2374 C C . PRO A 1 319 ? 12.858 111.371 -37.471 1.00 8.52 ? 375 PRO B C 1 ATOM 2375 O O . PRO A 1 319 ? 14.065 111.253 -37.250 1.00 15.92 ? 375 PRO B O 1 ATOM 2376 C CB . PRO A 1 319 ? 12.094 109.105 -38.260 1.00 7.04 ? 375 PRO B CB 1 ATOM 2377 C CG . PRO A 1 319 ? 13.259 108.458 -38.856 1.00 2.00 ? 375 PRO B CG 1 ATOM 2378 C CD . PRO A 1 319 ? 13.680 109.253 -40.050 1.00 2.00 ? 375 PRO B CD 1 ATOM 2379 N N . SER A 1 320 ? 12.051 112.143 -36.749 1.00 9.45 ? 376 SER B N 1 ATOM 2380 C CA . SER A 1 320 ? 12.540 112.899 -35.588 1.00 13.88 ? 376 SER B CA 1 ATOM 2381 C C . SER A 1 320 ? 12.990 112.008 -34.437 1.00 13.30 ? 376 SER B C 1 ATOM 2382 O O . SER A 1 320 ? 13.875 112.377 -33.664 1.00 25.13 ? 376 SER B O 1 ATOM 2383 C CB . SER A 1 320 ? 11.470 113.848 -35.091 1.00 20.00 ? 376 SER B CB 1 ATOM 2384 O OG . SER A 1 320 ? 10.250 113.147 -34.993 1.00 36.75 ? 376 SER B OG 1 ATOM 2385 N N . LEU A 1 321 ? 12.415 110.813 -34.348 1.00 16.69 ? 377 LEU B N 1 ATOM 2386 C CA . LEU A 1 321 ? 12.781 109.847 -33.309 1.00 18.23 ? 377 LEU B CA 1 ATOM 2387 C C . LEU A 1 321 ? 14.238 109.413 -33.425 1.00 16.15 ? 377 LEU B C 1 ATOM 2388 O O . LEU A 1 321 ? 14.736 108.650 -32.614 1.00 18.86 ? 377 LEU B O 1 ATOM 2389 C CB . LEU A 1 321 ? 11.839 108.643 -33.294 1.00 20.64 ? 377 LEU B CB 1 ATOM 2390 C CG . LEU A 1 321 ? 10.586 108.931 -32.455 1.00 27.49 ? 377 LEU B CG 1 ATOM 2391 C CD1 . LEU A 1 321 ? 9.609 107.744 -32.410 1.00 23.29 ? 377 LEU B CD1 1 ATOM 2392 C CD2 . LEU A 1 321 ? 10.981 109.382 -31.046 1.00 20.81 ? 377 LEU B CD2 1 ATOM 2393 N N . MET A 1 322 ? 14.904 109.903 -34.459 1.00 10.86 ? 378 MET B N 1 ATOM 2394 C CA . MET A 1 322 ? 16.345 109.799 -34.584 1.00 19.25 ? 378 MET B CA 1 ATOM 2395 C C . MET A 1 322 ? 17.017 110.229 -33.280 1.00 20.13 ? 378 MET B C 1 ATOM 2396 O O . MET A 1 322 ? 18.097 109.735 -32.920 1.00 23.22 ? 378 MET B O 1 ATOM 2397 C CB . MET A 1 322 ? 16.795 110.730 -35.696 1.00 23.07 ? 378 MET B CB 1 ATOM 2398 C CG . MET A 1 322 ? 17.864 110.173 -36.562 1.00 30.33 ? 378 MET B CG 1 ATOM 2399 S SD . MET A 1 322 ? 17.311 108.976 -37.768 1.00 25.96 ? 378 MET B SD 1 ATOM 2400 C CE . MET A 1 322 ? 18.943 108.447 -38.281 1.00 20.13 ? 378 MET B CE 1 ATOM 2401 N N . SER A 1 323 ? 16.383 111.165 -32.579 1.00 14.31 ? 379 SER B N 1 ATOM 2402 C CA . SER A 1 323 ? 16.926 111.661 -31.315 1.00 12.50 ? 379 SER B CA 1 ATOM 2403 C C . SER A 1 323 ? 17.124 110.556 -30.271 1.00 14.72 ? 379 SER B C 1 ATOM 2404 O O . SER A 1 323 ? 17.896 110.719 -29.328 1.00 11.36 ? 379 SER B O 1 ATOM 2405 C CB . SER A 1 323 ? 16.009 112.731 -30.752 1.00 11.49 ? 379 SER B CB 1 ATOM 2406 O OG . SER A 1 323 ? 14.669 112.305 -30.865 1.00 10.21 ? 379 SER B OG 1 ATOM 2407 N N . ASN A 1 324 ? 16.429 109.435 -30.438 1.00 14.31 ? 380 ASN B N 1 ATOM 2408 C CA . ASN A 1 324 ? 16.614 108.297 -29.550 1.00 9.58 ? 380 ASN B CA 1 ATOM 2409 C C . ASN A 1 324 ? 17.882 107.498 -29.802 1.00 17.00 ? 380 ASN B C 1 ATOM 2410 O O . ASN A 1 324 ? 18.229 106.645 -28.993 1.00 24.92 ? 380 ASN B O 1 ATOM 2411 C CB . ASN A 1 324 ? 15.401 107.361 -29.570 1.00 17.10 ? 380 ASN B CB 1 ATOM 2412 C CG . ASN A 1 324 ? 14.442 107.647 -28.445 1.00 35.39 ? 380 ASN B CG 1 ATOM 2413 O OD1 . ASN A 1 324 ? 13.419 108.294 -28.642 1.00 40.54 ? 380 ASN B OD1 1 ATOM 2414 N ND2 . ASN A 1 324 ? 14.782 107.189 -27.242 1.00 43.46 ? 380 ASN B ND2 1 ATOM 2415 N N . LEU A 1 325 ? 18.586 107.749 -30.903 1.00 15.63 ? 381 LEU B N 1 ATOM 2416 C CA . LEU A 1 325 ? 19.836 107.034 -31.086 1.00 14.01 ? 381 LEU B CA 1 ATOM 2417 C C . LEU A 1 325 ? 20.907 107.919 -30.491 1.00 18.70 ? 381 LEU B C 1 ATOM 2418 O O . LEU A 1 325 ? 21.502 108.745 -31.191 1.00 16.76 ? 381 LEU B O 1 ATOM 2419 C CB . LEU A 1 325 ? 20.108 106.867 -32.585 1.00 3.34 ? 381 LEU B CB 1 ATOM 2420 C CG . LEU A 1 325 ? 18.972 106.193 -33.360 1.00 9.60 ? 381 LEU B CG 1 ATOM 2421 C CD1 . LEU A 1 325 ? 19.118 106.315 -34.877 1.00 4.70 ? 381 LEU B CD1 1 ATOM 2422 C CD2 . LEU A 1 325 ? 18.845 104.725 -32.938 1.00 10.80 ? 381 LEU B CD2 1 ATOM 2423 N N . ARG A 1 326 ? 21.261 107.637 -29.244 1.00 17.97 ? 382 ARG B N 1 ATOM 2424 C CA . ARG A 1 326 ? 22.086 108.569 -28.477 1.00 16.26 ? 382 ARG B CA 1 ATOM 2425 C C . ARG A 1 326 ? 23.544 108.257 -28.674 1.00 12.55 ? 382 ARG B C 1 ATOM 2426 O O . ARG A 1 326 ? 24.401 109.023 -28.248 1.00 16.66 ? 382 ARG B O 1 ATOM 2427 C CB . ARG A 1 326 ? 21.733 108.552 -26.983 1.00 5.83 ? 382 ARG B CB 1 ATOM 2428 C CG . ARG A 1 326 ? 20.333 109.070 -26.669 1.00 9.04 ? 382 ARG B CG 1 ATOM 2429 C CD . ARG A 1 326 ? 20.247 110.561 -26.937 1.00 25.01 ? 382 ARG B CD 1 ATOM 2430 N NE . ARG A 1 326 ? 18.882 110.983 -27.226 1.00 36.78 ? 382 ARG B NE 1 ATOM 2431 C CZ . ARG A 1 326 ? 18.019 111.416 -26.312 1.00 44.95 ? 382 ARG B CZ 1 ATOM 2432 N NH1 . ARG A 1 326 ? 18.379 111.485 -25.036 1.00 46.64 ? 382 ARG B NH1 1 ATOM 2433 N NH2 . ARG A 1 326 ? 16.792 111.780 -26.679 1.00 46.38 ? 382 ARG B NH2 1 ATOM 2434 N N . SER A 1 327 ? 23.824 107.115 -29.296 1.00 8.93 ? 383 SER B N 1 ATOM 2435 C CA . SER A 1 327 ? 25.198 106.760 -29.621 1.00 12.02 ? 383 SER B CA 1 ATOM 2436 C C . SER A 1 327 ? 25.628 107.003 -31.066 1.00 14.84 ? 383 SER B C 1 ATOM 2437 O O . SER A 1 327 ? 26.774 106.712 -31.407 1.00 21.67 ? 383 SER B O 1 ATOM 2438 C CB . SER A 1 327 ? 25.487 105.318 -29.212 1.00 16.17 ? 383 SER B CB 1 ATOM 2439 O OG . SER A 1 327 ? 25.531 105.216 -27.798 1.00 13.25 ? 383 SER B OG 1 ATOM 2440 N N . LEU A 1 328 ? 24.730 107.524 -31.908 1.00 11.17 ? 384 LEU B N 1 ATOM 2441 C CA . LEU A 1 328 ? 25.037 107.695 -33.333 1.00 7.52 ? 384 LEU B CA 1 ATOM 2442 C C . LEU A 1 328 ? 26.249 108.595 -33.537 1.00 6.00 ? 384 LEU B C 1 ATOM 2443 O O . LEU A 1 328 ? 26.241 109.740 -33.125 1.00 12.25 ? 384 LEU B O 1 ATOM 2444 C CB . LEU A 1 328 ? 23.841 108.348 -34.028 1.00 9.88 ? 384 LEU B CB 1 ATOM 2445 C CG . LEU A 1 328 ? 23.664 108.231 -35.547 1.00 4.96 ? 384 LEU B CG 1 ATOM 2446 C CD1 . LEU A 1 328 ? 23.492 106.784 -35.889 1.00 3.76 ? 384 LEU B CD1 1 ATOM 2447 C CD2 . LEU A 1 328 ? 22.441 109.009 -35.986 1.00 2.00 ? 384 LEU B CD2 1 ATOM 2448 N N . THR A 1 329 ? 27.307 108.088 -34.155 1.00 8.36 ? 385 THR B N 1 ATOM 2449 C CA . THR A 1 329 ? 28.391 108.979 -34.560 1.00 12.97 ? 385 THR B CA 1 ATOM 2450 C C . THR A 1 329 ? 28.426 109.318 -36.048 1.00 12.10 ? 385 THR B C 1 ATOM 2451 O O . THR A 1 329 ? 29.013 110.324 -36.439 1.00 14.22 ? 385 THR B O 1 ATOM 2452 C CB . THR A 1 329 ? 29.753 108.404 -34.136 1.00 17.64 ? 385 THR B CB 1 ATOM 2453 O OG1 . THR A 1 329 ? 30.100 107.314 -35.003 1.00 19.95 ? 385 THR B OG1 1 ATOM 2454 C CG2 . THR A 1 329 ? 29.675 107.905 -32.697 1.00 2.61 ? 385 THR B CG2 1 ATOM 2455 N N . MET A 1 330 ? 27.760 108.507 -36.866 1.00 8.67 ? 386 MET B N 1 ATOM 2456 C CA . MET A 1 330 ? 27.868 108.630 -38.329 1.00 12.07 ? 386 MET B CA 1 ATOM 2457 C C . MET A 1 330 ? 26.518 108.417 -39.021 1.00 10.91 ? 386 MET B C 1 ATOM 2458 O O . MET A 1 330 ? 25.921 107.348 -38.886 1.00 9.68 ? 386 MET B O 1 ATOM 2459 C CB . MET A 1 330 ? 28.921 107.648 -38.876 1.00 16.96 ? 386 MET B CB 1 ATOM 2460 C CG . MET A 1 330 ? 29.099 107.681 -40.407 1.00 34.47 ? 386 MET B CG 1 ATOM 2461 S SD . MET A 1 330 ? 30.630 106.936 -41.073 1.00 35.47 ? 386 MET B SD 1 ATOM 2462 C CE . MET A 1 330 ? 31.751 107.299 -39.715 1.00 9.96 ? 386 MET B CE 1 ATOM 2463 N N . PHE A 1 331 ? 26.026 109.423 -39.743 1.00 2.00 ? 387 PHE B N 1 ATOM 2464 C CA . PHE A 1 331 ? 24.773 109.252 -40.480 1.00 2.00 ? 387 PHE B CA 1 ATOM 2465 C C . PHE A 1 331 ? 24.946 109.670 -41.948 1.00 12.14 ? 387 PHE B C 1 ATOM 2466 O O . PHE A 1 331 ? 25.063 110.864 -42.258 1.00 20.80 ? 387 PHE B O 1 ATOM 2467 C CB . PHE A 1 331 ? 23.677 110.078 -39.809 1.00 2.00 ? 387 PHE B CB 1 ATOM 2468 C CG . PHE A 1 331 ? 22.324 109.942 -40.438 1.00 9.11 ? 387 PHE B CG 1 ATOM 2469 C CD1 . PHE A 1 331 ? 21.896 108.733 -40.959 1.00 10.68 ? 387 PHE B CD1 1 ATOM 2470 C CD2 . PHE A 1 331 ? 21.458 111.024 -40.476 1.00 8.66 ? 387 PHE B CD2 1 ATOM 2471 C CE1 . PHE A 1 331 ? 20.640 108.611 -41.535 1.00 7.77 ? 387 PHE B CE1 1 ATOM 2472 C CE2 . PHE A 1 331 ? 20.205 110.900 -41.048 1.00 7.91 ? 387 PHE B CE2 1 ATOM 2473 C CZ . PHE A 1 331 ? 19.796 109.688 -41.567 1.00 2.00 ? 387 PHE B CZ 1 ATOM 2474 N N . PHE A 1 332 ? 24.936 108.685 -42.845 1.00 4.97 ? 388 PHE B N 1 ATOM 2475 C CA . PHE A 1 332 ? 25.058 108.934 -44.282 1.00 2.16 ? 388 PHE B CA 1 ATOM 2476 C C . PHE A 1 332 ? 23.795 108.417 -44.976 1.00 11.71 ? 388 PHE B C 1 ATOM 2477 O O . PHE A 1 332 ? 23.563 107.192 -45.056 1.00 9.86 ? 388 PHE B O 1 ATOM 2478 C CB . PHE A 1 332 ? 26.250 108.149 -44.860 1.00 2.00 ? 388 PHE B CB 1 ATOM 2479 C CG . PHE A 1 332 ? 27.609 108.692 -44.481 1.00 4.84 ? 388 PHE B CG 1 ATOM 2480 C CD1 . PHE A 1 332 ? 27.745 109.777 -43.623 1.00 5.10 ? 388 PHE B CD1 1 ATOM 2481 C CD2 . PHE A 1 332 ? 28.758 108.124 -45.021 1.00 5.23 ? 388 PHE B CD2 1 ATOM 2482 C CE1 . PHE A 1 332 ? 29.014 110.280 -43.286 1.00 9.45 ? 388 PHE B CE1 1 ATOM 2483 C CE2 . PHE A 1 332 ? 30.014 108.621 -44.704 1.00 12.72 ? 388 PHE B CE2 1 ATOM 2484 C CZ . PHE A 1 332 ? 30.144 109.705 -43.828 1.00 10.75 ? 388 PHE B CZ 1 ATOM 2485 N N . ALA A 1 333 ? 22.948 109.351 -45.396 1.00 12.51 ? 389 ALA B N 1 ATOM 2486 C CA . ALA A 1 333 ? 21.819 109.106 -46.300 1.00 10.99 ? 389 ALA B CA 1 ATOM 2487 C C . ALA A 1 333 ? 21.961 109.676 -47.720 1.00 17.10 ? 389 ALA B C 1 ATOM 2488 O O . ALA A 1 333 ? 20.974 109.744 -48.451 1.00 22.24 ? 389 ALA B O 1 ATOM 2489 C CB . ALA A 1 333 ? 20.504 109.541 -45.668 1.00 12.77 ? 389 ALA B CB 1 ATOM 2490 N N . TRP A 1 334 ? 23.132 110.196 -48.071 1.00 12.80 ? 390 TRP B N 1 ATOM 2491 C CA . TRP A 1 334 ? 23.268 110.947 -49.323 1.00 3.70 ? 390 TRP B CA 1 ATOM 2492 C C . TRP A 1 334 ? 22.869 110.161 -50.580 1.00 4.97 ? 390 TRP B C 1 ATOM 2493 O O . TRP A 1 334 ? 22.928 108.930 -50.587 1.00 6.18 ? 390 TRP B O 1 ATOM 2494 C CB . TRP A 1 334 ? 24.665 111.574 -49.456 1.00 6.17 ? 390 TRP B CB 1 ATOM 2495 C CG . TRP A 1 334 ? 25.861 110.626 -49.525 1.00 12.54 ? 390 TRP B CG 1 ATOM 2496 C CD1 . TRP A 1 334 ? 26.509 110.023 -48.472 1.00 12.88 ? 390 TRP B CD1 1 ATOM 2497 C CD2 . TRP A 1 334 ? 26.582 110.238 -50.710 1.00 12.24 ? 390 TRP B CD2 1 ATOM 2498 N NE1 . TRP A 1 334 ? 27.567 109.257 -48.941 1.00 12.88 ? 390 TRP B NE1 1 ATOM 2499 C CE2 . TRP A 1 334 ? 27.635 109.382 -50.306 1.00 13.09 ? 390 TRP B CE2 1 ATOM 2500 C CE3 . TRP A 1 334 ? 26.434 110.526 -52.075 1.00 14.03 ? 390 TRP B CE3 1 ATOM 2501 C CZ2 . TRP A 1 334 ? 28.537 108.820 -51.220 1.00 14.04 ? 390 TRP B CZ2 1 ATOM 2502 C CZ3 . TRP A 1 334 ? 27.333 109.960 -52.984 1.00 4.31 ? 390 TRP B CZ3 1 ATOM 2503 C CH2 . TRP A 1 334 ? 28.365 109.120 -52.551 1.00 3.81 ? 390 TRP B CH2 1 ATOM 2504 N N . GLN A 1 335 ? 22.406 110.878 -51.611 1.00 5.03 ? 391 GLN B N 1 ATOM 2505 C CA . GLN A 1 335 ? 21.942 110.276 -52.877 1.00 2.00 ? 391 GLN B CA 1 ATOM 2506 C C . GLN A 1 335 ? 20.779 109.323 -52.631 1.00 7.34 ? 391 GLN B C 1 ATOM 2507 O O . GLN A 1 335 ? 20.897 108.097 -52.793 1.00 9.54 ? 391 GLN B O 1 ATOM 2508 C CB . GLN A 1 335 ? 23.091 109.581 -53.638 1.00 2.00 ? 391 GLN B CB 1 ATOM 2509 C CG . GLN A 1 335 ? 22.742 109.087 -55.035 1.00 7.55 ? 391 GLN B CG 1 ATOM 2510 C CD . GLN A 1 335 ? 22.241 110.200 -55.960 1.00 11.76 ? 391 GLN B CD 1 ATOM 2511 O OE1 . GLN A 1 335 ? 23.035 110.938 -56.534 1.00 12.49 ? 391 GLN B OE1 1 ATOM 2512 N NE2 . GLN A 1 335 ? 20.916 110.336 -56.076 1.00 13.44 ? 391 GLN B NE2 1 ATOM 2513 N N . ASN A 1 336 ? 19.659 109.905 -52.207 1.00 2.60 ? 392 ASN B N 1 ATOM 2514 C CA . ASN A 1 336 ? 18.395 109.198 -52.082 1.00 2.00 ? 392 ASN B CA 1 ATOM 2515 C C . ASN A 1 336 ? 17.297 110.145 -52.542 1.00 4.57 ? 392 ASN B C 1 ATOM 2516 O O . ASN A 1 336 ? 17.582 111.216 -53.057 1.00 9.55 ? 392 ASN B O 1 ATOM 2517 C CB . ASN A 1 336 ? 18.158 108.789 -50.622 1.00 9.71 ? 392 ASN B CB 1 ATOM 2518 C CG . ASN A 1 336 ? 18.770 107.437 -50.280 1.00 13.93 ? 392 ASN B CG 1 ATOM 2519 O OD1 . ASN A 1 336 ? 18.285 106.389 -50.730 1.00 12.81 ? 392 ASN B OD1 1 ATOM 2520 N ND2 . ASN A 1 336 ? 19.833 107.451 -49.469 1.00 11.26 ? 392 ASN B ND2 1 ATOM 2521 N N . LYS A 1 337 ? 16.045 109.744 -52.352 1.00 9.64 ? 393 LYS B N 1 ATOM 2522 C CA . LYS A 1 337 ? 14.848 110.563 -52.626 1.00 5.41 ? 393 LYS B CA 1 ATOM 2523 C C . LYS A 1 337 ? 14.221 111.266 -51.395 1.00 14.76 ? 393 LYS B C 1 ATOM 2524 O O . LYS A 1 337 ? 13.003 111.496 -51.387 1.00 15.97 ? 393 LYS B O 1 ATOM 2525 C CB . LYS A 1 337 ? 13.800 109.771 -53.402 1.00 11.64 ? 393 LYS B CB 1 ATOM 2526 C CG . LYS A 1 337 ? 14.333 109.095 -54.662 1.00 19.49 ? 393 LYS B CG 1 ATOM 2527 C CD . LYS A 1 337 ? 14.848 110.141 -55.606 1.00 35.48 ? 393 LYS B CD 1 ATOM 2528 C CE . LYS A 1 337 ? 15.538 109.547 -56.838 1.00 48.59 ? 393 LYS B CE 1 ATOM 2529 N NZ . LYS A 1 337 ? 16.165 110.632 -57.685 1.00 51.87 ? 393 LYS B NZ 1 ATOM 2530 N N . LEU A 1 338 ? 14.977 111.412 -50.302 1.00 11.28 ? 394 LEU B N 1 ATOM 2531 C CA . LEU A 1 338 ? 14.464 112.059 -49.084 1.00 4.26 ? 394 LEU B CA 1 ATOM 2532 C C . LEU A 1 338 ? 13.877 113.465 -49.260 1.00 8.12 ? 394 LEU B C 1 ATOM 2533 O O . LEU A 1 338 ? 14.461 114.317 -49.938 1.00 13.03 ? 394 LEU B O 1 ATOM 2534 C CB . LEU A 1 338 ? 15.552 112.122 -48.008 1.00 2.44 ? 394 LEU B CB 1 ATOM 2535 C CG . LEU A 1 338 ? 16.160 110.805 -47.523 1.00 8.87 ? 394 LEU B CG 1 ATOM 2536 C CD1 . LEU A 1 338 ? 17.304 111.070 -46.535 1.00 5.69 ? 394 LEU B CD1 1 ATOM 2537 C CD2 . LEU A 1 338 ? 15.109 109.925 -46.892 1.00 5.26 ? 394 LEU B CD2 1 ATOM 2538 N N . THR A 1 339 ? 12.736 113.711 -48.619 1.00 4.38 ? 395 THR B N 1 ATOM 2539 C CA . THR A 1 339 ? 12.118 115.035 -48.633 1.00 5.06 ? 395 THR B CA 1 ATOM 2540 C C . THR A 1 339 ? 11.786 115.482 -47.229 1.00 9.27 ? 395 THR B C 1 ATOM 2541 O O . THR A 1 339 ? 11.950 114.720 -46.281 1.00 22.28 ? 395 THR B O 1 ATOM 2542 C CB . THR A 1 339 ? 10.793 115.044 -49.436 1.00 12.59 ? 395 THR B CB 1 ATOM 2543 O OG1 . THR A 1 339 ? 9.836 114.194 -48.790 1.00 15.24 ? 395 THR B OG1 1 ATOM 2544 C CG2 . THR A 1 339 ? 11.026 114.563 -50.857 1.00 11.72 ? 395 THR B CG2 1 ATOM 2545 N N . GLY A 1 340 ? 11.267 116.702 -47.105 1.00 8.34 ? 396 GLY B N 1 ATOM 2546 C CA . GLY A 1 340 ? 10.877 117.243 -45.811 1.00 5.72 ? 396 GLY B CA 1 ATOM 2547 C C . GLY A 1 340 ? 12.032 117.993 -45.174 1.00 10.26 ? 396 GLY B C 1 ATOM 2548 O O . GLY A 1 340 ? 13.107 118.106 -45.779 1.00 11.44 ? 396 GLY B O 1 ATOM 2549 N N . ASN A 1 341 ? 11.805 118.516 -43.967 1.00 6.60 ? 397 ASN B N 1 ATOM 2550 C CA . ASN A 1 341 ? 12.842 119.209 -43.211 1.00 2.06 ? 397 ASN B CA 1 ATOM 2551 C C . ASN A 1 341 ? 13.869 118.252 -42.666 1.00 13.31 ? 397 ASN B C 1 ATOM 2552 O O . ASN A 1 341 ? 13.594 117.070 -42.472 1.00 19.81 ? 397 ASN B O 1 ATOM 2553 C CB . ASN A 1 341 ? 12.247 119.977 -42.031 1.00 2.42 ? 397 ASN B CB 1 ATOM 2554 C CG . ASN A 1 341 ? 11.721 121.350 -42.420 1.00 13.01 ? 397 ASN B CG 1 ATOM 2555 O OD1 . ASN A 1 341 ? 10.665 121.468 -43.021 1.00 13.70 ? 397 ASN B OD1 1 ATOM 2556 N ND2 . ASN A 1 341 ? 12.441 122.396 -42.037 1.00 21.65 ? 397 ASN B ND2 1 ATOM 2557 N N . ILE A 1 342 ? 15.067 118.766 -42.432 1.00 17.23 ? 398 ILE B N 1 ATOM 2558 C CA . ILE A 1 342 ? 16.035 118.074 -41.602 1.00 12.68 ? 398 ILE B CA 1 ATOM 2559 C C . ILE A 1 342 ? 15.572 118.295 -40.168 1.00 3.68 ? 398 ILE B C 1 ATOM 2560 O O . ILE A 1 342 ? 15.464 119.426 -39.735 1.00 3.61 ? 398 ILE B O 1 ATOM 2561 C CB . ILE A 1 342 ? 17.411 118.715 -41.736 1.00 12.34 ? 398 ILE B CB 1 ATOM 2562 C CG1 . ILE A 1 342 ? 17.922 118.601 -43.171 1.00 6.37 ? 398 ILE B CG1 1 ATOM 2563 C CG2 . ILE A 1 342 ? 18.384 118.095 -40.739 1.00 19.70 ? 398 ILE B CG2 1 ATOM 2564 C CD1 . ILE A 1 342 ? 19.110 119.489 -43.451 1.00 2.00 ? 398 ILE B CD1 1 ATOM 2565 N N . PRO A 1 343 ? 15.286 117.217 -39.434 1.00 7.21 ? 399 PRO B N 1 ATOM 2566 C CA . PRO A 1 343 ? 14.738 117.364 -38.075 1.00 9.83 ? 399 PRO B CA 1 ATOM 2567 C C . PRO A 1 343 ? 15.736 117.959 -37.080 1.00 14.13 ? 399 PRO B C 1 ATOM 2568 O O . PRO A 1 343 ? 16.851 117.442 -36.955 1.00 14.03 ? 399 PRO B O 1 ATOM 2569 C CB . PRO A 1 343 ? 14.430 115.915 -37.674 1.00 17.31 ? 399 PRO B CB 1 ATOM 2570 C CG . PRO A 1 343 ? 15.436 115.086 -38.494 1.00 13.86 ? 399 PRO B CG 1 ATOM 2571 C CD . PRO A 1 343 ? 15.507 115.807 -39.811 1.00 3.10 ? 399 PRO B CD 1 ATOM 2572 N N . GLN A 1 344 ? 15.321 118.991 -36.346 1.00 16.49 ? 400 GLN B N 1 ATOM 2573 C CA . GLN A 1 344 ? 16.140 119.542 -35.263 1.00 21.73 ? 400 GLN B CA 1 ATOM 2574 C C . GLN A 1 344 ? 16.514 118.485 -34.201 1.00 18.49 ? 400 GLN B C 1 ATOM 2575 O O . GLN A 1 344 ? 17.551 118.603 -33.532 1.00 14.11 ? 400 GLN B O 1 ATOM 2576 C CB . GLN A 1 344 ? 15.435 120.734 -34.590 1.00 18.99 ? 400 GLN B CB 1 ATOM 2577 C CG . GLN A 1 344 ? 14.243 120.361 -33.717 1.00 29.27 ? 400 GLN B CG 1 ATOM 2578 C CD . GLN A 1 344 ? 14.494 120.604 -32.226 1.00 42.28 ? 400 GLN B CD 1 ATOM 2579 O OE1 . GLN A 1 344 ? 14.680 121.745 -31.800 1.00 47.03 ? 400 GLN B OE1 1 ATOM 2580 N NE2 . GLN A 1 344 ? 14.501 119.530 -31.431 1.00 43.48 ? 400 GLN B NE2 1 ATOM 2581 N N . SER A 1 345 ? 15.677 117.455 -34.065 1.00 8.54 ? 401 SER B N 1 ATOM 2582 C CA . SER A 1 345 ? 15.851 116.445 -33.026 1.00 3.86 ? 401 SER B CA 1 ATOM 2583 C C . SER A 1 345 ? 17.104 115.622 -33.257 1.00 15.10 ? 401 SER B C 1 ATOM 2584 O O . SER A 1 345 ? 17.573 114.921 -32.368 1.00 28.37 ? 401 SER B O 1 ATOM 2585 C CB . SER A 1 345 ? 14.639 115.523 -32.958 1.00 10.06 ? 401 SER B CB 1 ATOM 2586 O OG . SER A 1 345 ? 14.599 114.673 -34.087 1.00 18.31 ? 401 SER B OG 1 ATOM 2587 N N . LEU A 1 346 ? 17.642 115.711 -34.462 1.00 13.43 ? 402 LEU B N 1 ATOM 2588 C CA . LEU A 1 346 ? 18.904 115.068 -34.795 1.00 8.44 ? 402 LEU B CA 1 ATOM 2589 C C . LEU A 1 346 ? 20.029 115.641 -33.937 1.00 18.74 ? 402 LEU B C 1 ATOM 2590 O O . LEU A 1 346 ? 21.021 114.963 -33.664 1.00 31.11 ? 402 LEU B O 1 ATOM 2591 C CB . LEU A 1 346 ? 19.195 115.274 -36.277 1.00 8.45 ? 402 LEU B CB 1 ATOM 2592 C CG . LEU A 1 346 ? 20.118 114.333 -37.042 1.00 20.30 ? 402 LEU B CG 1 ATOM 2593 C CD1 . LEU A 1 346 ? 19.888 112.916 -36.615 1.00 23.11 ? 402 LEU B CD1 1 ATOM 2594 C CD2 . LEU A 1 346 ? 19.876 114.474 -38.553 1.00 21.11 ? 402 LEU B CD2 1 ATOM 2595 N N . SER A 1 347 ? 19.863 116.881 -33.482 1.00 14.10 ? 403 SER B N 1 ATOM 2596 C CA . SER A 1 347 ? 20.823 117.479 -32.560 1.00 19.85 ? 403 SER B CA 1 ATOM 2597 C C . SER A 1 347 ? 20.840 116.812 -31.165 1.00 18.14 ? 403 SER B C 1 ATOM 2598 O O . SER A 1 347 ? 21.698 117.131 -30.333 1.00 17.18 ? 403 SER B O 1 ATOM 2599 C CB . SER A 1 347 ? 20.551 118.973 -32.404 1.00 23.69 ? 403 SER B CB 1 ATOM 2600 O OG . SER A 1 347 ? 19.497 119.196 -31.481 1.00 19.74 ? 403 SER B OG 1 ATOM 2601 N N . GLN A 1 348 ? 19.899 115.912 -30.883 1.00 7.62 ? 404 GLN B N 1 ATOM 2602 C CA . GLN A 1 348 ? 19.961 115.227 -29.593 1.00 11.83 ? 404 GLN B CA 1 ATOM 2603 C C . GLN A 1 348 ? 20.928 114.042 -29.585 1.00 19.29 ? 404 GLN B C 1 ATOM 2604 O O . GLN A 1 348 ? 21.227 113.504 -28.522 1.00 25.78 ? 404 GLN B O 1 ATOM 2605 C CB . GLN A 1 348 ? 18.583 114.814 -29.088 1.00 11.86 ? 404 GLN B CB 1 ATOM 2606 C CG . GLN A 1 348 ? 17.688 115.982 -28.728 1.00 9.24 ? 404 GLN B CG 1 ATOM 2607 C CD . GLN A 1 348 ? 16.305 115.527 -28.355 1.00 27.11 ? 404 GLN B CD 1 ATOM 2608 O OE1 . GLN A 1 348 ? 16.142 114.592 -27.573 1.00 43.32 ? 404 GLN B OE1 1 ATOM 2609 N NE2 . GLN A 1 348 ? 15.296 116.169 -28.923 1.00 30.39 ? 404 GLN B NE2 1 ATOM 2610 N N . CYS A 1 349 ? 21.455 113.664 -30.749 1.00 21.37 ? 405 CYS B N 1 ATOM 2611 C CA . CYS A 1 349 ? 22.461 112.609 -30.768 1.00 14.84 ? 405 CYS B CA 1 ATOM 2612 C C . CYS A 1 349 ? 23.737 113.374 -30.629 1.00 19.87 ? 405 CYS B C 1 ATOM 2613 O O . CYS A 1 349 ? 24.271 113.896 -31.614 1.00 21.49 ? 405 CYS B O 1 ATOM 2614 C CB . CYS A 1 349 ? 22.480 111.899 -32.133 1.00 9.24 ? 405 CYS B CB 1 ATOM 2615 S SG . CYS A 1 349 ? 20.862 111.455 -32.826 1.00 13.32 ? 405 CYS B SG 1 ATOM 2616 N N . ARG A 1 350 ? 24.285 113.376 -29.423 1.00 25.35 ? 406 ARG B N 1 ATOM 2617 C CA . ARG A 1 350 ? 25.323 114.350 -29.113 1.00 22.82 ? 406 ARG B CA 1 ATOM 2618 C C . ARG A 1 350 ? 26.687 113.867 -29.624 1.00 13.13 ? 406 ARG B C 1 ATOM 2619 O O . ARG A 1 350 ? 27.623 114.643 -29.725 1.00 15.19 ? 406 ARG B O 1 ATOM 2620 C CB . ARG A 1 350 ? 25.344 114.696 -27.606 1.00 21.21 ? 406 ARG B CB 1 ATOM 2621 C CG . ARG A 1 350 ? 24.027 115.244 -27.015 1.00 19.73 ? 406 ARG B CG 1 ATOM 2622 C CD . ARG A 1 350 ? 23.580 116.574 -27.653 1.00 22.94 ? 406 ARG B CD 1 ATOM 2623 N NE . ARG A 1 350 ? 24.552 117.651 -27.458 1.00 25.12 ? 406 ARG B NE 1 ATOM 2624 C CZ . ARG A 1 350 ? 24.532 118.834 -28.079 1.00 24.20 ? 406 ARG B CZ 1 ATOM 2625 N NH1 . ARG A 1 350 ? 23.587 119.143 -28.965 1.00 23.91 ? 406 ARG B NH1 1 ATOM 2626 N NH2 . ARG A 1 350 ? 25.476 119.722 -27.815 1.00 25.03 ? 406 ARG B NH2 1 ATOM 2627 N N . GLU A 1 351 ? 26.789 112.586 -29.963 1.00 7.59 ? 407 GLU B N 1 ATOM 2628 C CA . GLU A 1 351 ? 28.056 112.034 -30.446 1.00 11.51 ? 407 GLU B CA 1 ATOM 2629 C C . GLU A 1 351 ? 28.341 112.220 -31.944 1.00 13.86 ? 407 GLU B C 1 ATOM 2630 O O . GLU A 1 351 ? 29.433 111.861 -32.381 1.00 17.48 ? 407 GLU B O 1 ATOM 2631 C CB . GLU A 1 351 ? 28.166 110.534 -30.125 1.00 11.43 ? 407 GLU B CB 1 ATOM 2632 C CG . GLU A 1 351 ? 27.700 110.132 -28.741 1.00 20.17 ? 407 GLU B CG 1 ATOM 2633 C CD . GLU A 1 351 ? 28.489 110.794 -27.628 1.00 34.03 ? 407 GLU B CD 1 ATOM 2634 O OE1 . GLU A 1 351 ? 27.871 111.184 -26.610 1.00 46.01 ? 407 GLU B OE1 1 ATOM 2635 O OE2 . GLU A 1 351 ? 29.726 110.917 -27.761 1.00 34.35 ? 407 GLU B OE2 1 ATOM 2636 N N . LEU A 1 352 ? 27.403 112.768 -32.728 1.00 9.20 ? 408 LEU B N 1 ATOM 2637 C CA . LEU A 1 352 ? 27.578 112.769 -34.196 1.00 14.18 ? 408 LEU B CA 1 ATOM 2638 C C . LEU A 1 352 ? 28.876 113.422 -34.681 1.00 23.55 ? 408 LEU B C 1 ATOM 2639 O O . LEU A 1 352 ? 29.142 114.596 -34.432 1.00 24.29 ? 408 LEU B O 1 ATOM 2640 C CB . LEU A 1 352 ? 26.402 113.449 -34.894 1.00 8.24 ? 408 LEU B CB 1 ATOM 2641 C CG . LEU A 1 352 ? 25.131 112.620 -35.112 1.00 10.78 ? 408 LEU B CG 1 ATOM 2642 C CD1 . LEU A 1 352 ? 23.984 113.485 -35.638 1.00 5.10 ? 408 LEU B CD1 1 ATOM 2643 C CD2 . LEU A 1 352 ? 25.417 111.460 -36.041 1.00 6.26 ? 408 LEU B CD2 1 ATOM 2644 N N . GLN A 1 353 ? 29.693 112.626 -35.362 1.00 21.91 ? 409 GLN B N 1 ATOM 2645 C CA . GLN A 1 353 ? 30.895 113.125 -36.005 1.00 17.19 ? 409 GLN B CA 1 ATOM 2646 C C . GLN A 1 353 ? 30.690 113.600 -37.440 1.00 19.23 ? 409 GLN B C 1 ATOM 2647 O O . GLN A 1 353 ? 31.328 114.555 -37.887 1.00 18.39 ? 409 GLN B O 1 ATOM 2648 C CB . GLN A 1 353 ? 32.032 112.115 -35.870 1.00 12.93 ? 409 GLN B CB 1 ATOM 2649 C CG . GLN A 1 353 ? 32.518 112.000 -34.437 1.00 10.64 ? 409 GLN B CG 1 ATOM 2650 C CD . GLN A 1 353 ? 33.149 110.655 -34.118 1.00 16.59 ? 409 GLN B CD 1 ATOM 2651 O OE1 . GLN A 1 353 ? 33.637 109.948 -35.011 1.00 22.07 ? 409 GLN B OE1 1 ATOM 2652 N NE2 . GLN A 1 353 ? 33.132 110.289 -32.839 1.00 10.52 ? 409 GLN B NE2 1 ATOM 2653 N N . ALA A 1 354 ? 29.827 112.891 -38.167 1.00 17.56 ? 410 ALA B N 1 ATOM 2654 C CA . ALA A 1 354 ? 29.638 113.139 -39.595 1.00 6.10 ? 410 ALA B CA 1 ATOM 2655 C C . ALA A 1 354 ? 28.186 112.996 -40.034 1.00 8.39 ? 410 ALA B C 1 ATOM 2656 O O . ALA A 1 354 ? 27.548 111.952 -39.808 1.00 11.26 ? 410 ALA B O 1 ATOM 2657 C CB . ALA A 1 354 ? 30.514 112.208 -40.396 1.00 2.58 ? 410 ALA B CB 1 ATOM 2658 N N . ILE A 1 355 ? 27.672 114.039 -40.682 1.00 6.21 ? 411 ILE B N 1 ATOM 2659 C CA . ILE A 1 355 ? 26.353 113.972 -41.304 1.00 6.16 ? 411 ILE B CA 1 ATOM 2660 C C . ILE A 1 355 ? 26.492 114.205 -42.820 1.00 8.75 ? 411 ILE B C 1 ATOM 2661 O O . ILE A 1 355 ? 27.057 115.221 -43.221 1.00 4.96 ? 411 ILE B O 1 ATOM 2662 C CB . ILE A 1 355 ? 25.443 115.028 -40.697 1.00 2.00 ? 411 ILE B CB 1 ATOM 2663 C CG1 . ILE A 1 355 ? 25.507 114.941 -39.184 1.00 4.84 ? 411 ILE B CG1 1 ATOM 2664 C CG2 . ILE A 1 355 ? 24.016 114.852 -41.166 1.00 8.17 ? 411 ILE B CG2 1 ATOM 2665 C CD1 . ILE A 1 355 ? 24.717 116.020 -38.463 1.00 2.00 ? 411 ILE B CD1 1 ATOM 2666 N N . ASP A 1 356 ? 26.040 113.266 -43.660 1.00 9.71 ? 412 ASP B N 1 ATOM 2667 C CA . ASP A 1 356 ? 25.955 113.553 -45.110 1.00 2.81 ? 412 ASP B CA 1 ATOM 2668 C C . ASP A 1 356 ? 24.567 113.215 -45.653 1.00 4.59 ? 412 ASP B C 1 ATOM 2669 O O . ASP A 1 356 ? 24.176 112.048 -45.752 1.00 2.00 ? 412 ASP B O 1 ATOM 2670 C CB . ASP A 1 356 ? 27.039 112.811 -45.890 1.00 2.00 ? 412 ASP B CB 1 ATOM 2671 C CG . ASP A 1 356 ? 27.185 113.303 -47.343 1.00 23.92 ? 412 ASP B CG 1 ATOM 2672 O OD1 . ASP A 1 356 ? 26.286 114.003 -47.871 1.00 19.99 ? 412 ASP B OD1 1 ATOM 2673 O OD2 . ASP A 1 356 ? 28.215 112.970 -47.971 1.00 19.83 ? 412 ASP B OD2 1 ATOM 2674 N N . LEU A 1 357 ? 23.817 114.271 -45.948 1.00 8.41 ? 413 LEU B N 1 ATOM 2675 C CA . LEU A 1 357 ? 22.491 114.203 -46.546 1.00 2.00 ? 413 LEU B CA 1 ATOM 2676 C C . LEU A 1 357 ? 22.433 114.658 -48.007 1.00 8.24 ? 413 LEU B C 1 ATOM 2677 O O . LEU A 1 357 ? 21.353 114.953 -48.522 1.00 6.65 ? 413 LEU B O 1 ATOM 2678 C CB . LEU A 1 357 ? 21.446 114.864 -45.659 1.00 15.04 ? 413 LEU B CB 1 ATOM 2679 C CG . LEU A 1 357 ? 21.477 114.302 -44.223 1.00 16.22 ? 413 LEU B CG 1 ATOM 2680 C CD1 . LEU A 1 357 ? 20.499 115.027 -43.347 1.00 2.00 ? 413 LEU B CD1 1 ATOM 2681 C CD2 . LEU A 1 357 ? 21.209 112.799 -44.202 1.00 15.48 ? 413 LEU B CD2 1 ATOM 2682 N N . SER A 1 358 ? 23.593 114.810 -48.641 1.00 2.00 ? 414 SER B N 1 ATOM 2683 C CA . SER A 1 358 ? 23.675 115.447 -49.954 1.00 5.65 ? 414 SER B CA 1 ATOM 2684 C C . SER A 1 358 ? 22.843 114.677 -50.976 1.00 10.89 ? 414 SER B C 1 ATOM 2685 O O . SER A 1 358 ? 22.496 113.522 -50.745 1.00 9.76 ? 414 SER B O 1 ATOM 2686 C CB . SER A 1 358 ? 25.133 115.520 -50.451 1.00 7.19 ? 414 SER B CB 1 ATOM 2687 O OG . SER A 1 358 ? 26.053 115.962 -49.453 1.00 2.10 ? 414 SER B OG 1 ATOM 2688 N N . TYR A 1 359 ? 22.479 115.340 -52.076 1.00 9.35 ? 415 TYR B N 1 ATOM 2689 C CA . TYR A 1 359 ? 21.771 114.687 -53.178 1.00 4.62 ? 415 TYR B CA 1 ATOM 2690 C C . TYR A 1 359 ? 20.433 114.099 -52.779 1.00 2.93 ? 415 TYR B C 1 ATOM 2691 O O . TYR A 1 359 ? 20.177 112.919 -52.996 1.00 4.71 ? 415 TYR B O 1 ATOM 2692 C CB . TYR A 1 359 ? 22.638 113.604 -53.823 1.00 8.64 ? 415 TYR B CB 1 ATOM 2693 C CG . TYR A 1 359 ? 23.877 114.159 -54.471 1.00 2.00 ? 415 TYR B CG 1 ATOM 2694 C CD1 . TYR A 1 359 ? 23.797 114.910 -55.641 1.00 2.00 ? 415 TYR B CD1 1 ATOM 2695 C CD2 . TYR A 1 359 ? 25.123 113.941 -53.920 1.00 3.40 ? 415 TYR B CD2 1 ATOM 2696 C CE1 . TYR A 1 359 ? 24.936 115.422 -56.240 1.00 2.00 ? 415 TYR B CE1 1 ATOM 2697 C CE2 . TYR A 1 359 ? 26.267 114.459 -54.507 1.00 2.24 ? 415 TYR B CE2 1 ATOM 2698 C CZ . TYR A 1 359 ? 26.159 115.190 -55.661 1.00 5.18 ? 415 TYR B CZ 1 ATOM 2699 O OH . TYR A 1 359 ? 27.291 115.687 -56.232 1.00 20.87 ? 415 TYR B OH 1 ATOM 2700 N N . ASN A 1 360 ? 19.595 114.928 -52.166 1.00 8.02 ? 416 ASN B N 1 ATOM 2701 C CA . ASN A 1 360 ? 18.238 114.550 -51.840 1.00 2.00 ? 416 ASN B CA 1 ATOM 2702 C C . ASN A 1 360 ? 17.334 115.679 -52.272 1.00 6.95 ? 416 ASN B C 1 ATOM 2703 O O . ASN A 1 360 ? 17.750 116.579 -52.985 1.00 9.12 ? 416 ASN B O 1 ATOM 2704 C CB . ASN A 1 360 ? 18.076 114.286 -50.332 1.00 2.00 ? 416 ASN B CB 1 ATOM 2705 C CG . ASN A 1 360 ? 18.538 112.881 -49.916 1.00 5.95 ? 416 ASN B CG 1 ATOM 2706 O OD1 . ASN A 1 360 ? 17.881 111.894 -50.226 1.00 12.10 ? 416 ASN B OD1 1 ATOM 2707 N ND2 . ASN A 1 360 ? 19.657 112.797 -49.202 1.00 2.00 ? 416 ASN B ND2 1 ATOM 2708 N N . SER A 1 361 ? 16.070 115.579 -51.899 1.00 9.49 ? 417 SER B N 1 ATOM 2709 C CA . SER A 1 361 ? 15.101 116.650 -52.034 1.00 8.10 ? 417 SER B CA 1 ATOM 2710 C C . SER A 1 361 ? 14.784 117.438 -50.752 1.00 11.03 ? 417 SER B C 1 ATOM 2711 O O . SER A 1 361 ? 13.681 117.990 -50.623 1.00 12.98 ? 417 SER B O 1 ATOM 2712 C CB . SER A 1 361 ? 13.850 116.165 -52.734 1.00 10.10 ? 417 SER B CB 1 ATOM 2713 O OG . SER A 1 361 ? 14.147 115.991 -54.096 1.00 14.40 ? 417 SER B OG 1 ATOM 2714 N N . LEU A 1 362 ? 15.640 117.347 -49.745 1.00 5.55 ? 418 LEU B N 1 ATOM 2715 C CA . LEU A 1 362 ? 15.338 118.017 -48.474 1.00 11.61 ? 418 LEU B CA 1 ATOM 2716 C C . LEU A 1 362 ? 15.068 119.493 -48.692 1.00 11.05 ? 418 LEU B C 1 ATOM 2717 O O . LEU A 1 362 ? 15.652 120.112 -49.583 1.00 10.22 ? 418 LEU B O 1 ATOM 2718 C CB . LEU A 1 362 ? 16.474 117.828 -47.462 1.00 2.00 ? 418 LEU B CB 1 ATOM 2719 C CG . LEU A 1 362 ? 16.676 116.360 -47.086 1.00 2.00 ? 418 LEU B CG 1 ATOM 2720 C CD1 . LEU A 1 362 ? 18.050 116.111 -46.499 1.00 2.00 ? 418 LEU B CD1 1 ATOM 2721 C CD2 . LEU A 1 362 ? 15.565 115.920 -46.147 1.00 2.00 ? 418 LEU B CD2 1 ATOM 2722 N N . SER A 1 363 ? 14.163 120.054 -47.898 1.00 13.24 ? 419 SER B N 1 ATOM 2723 C CA . SER A 1 363 ? 13.840 121.461 -48.038 1.00 12.10 ? 419 SER B CA 1 ATOM 2724 C C . SER A 1 363 ? 13.715 122.088 -46.664 1.00 13.81 ? 419 SER B C 1 ATOM 2725 O O . SER A 1 363 ? 13.856 121.398 -45.666 1.00 18.33 ? 419 SER B O 1 ATOM 2726 C CB . SER A 1 363 ? 12.542 121.638 -48.832 1.00 13.63 ? 419 SER B CB 1 ATOM 2727 O OG . SER A 1 363 ? 11.452 121.016 -48.176 1.00 12.81 ? 419 SER B OG 1 ATOM 2728 N N . GLY A 1 364 ? 13.424 123.387 -46.619 1.00 11.61 ? 420 GLY B N 1 ATOM 2729 C CA . GLY A 1 364 ? 13.296 124.093 -45.362 1.00 2.80 ? 420 GLY B CA 1 ATOM 2730 C C . GLY A 1 364 ? 14.621 124.680 -44.905 1.00 22.14 ? 420 GLY B C 1 ATOM 2731 O O . GLY A 1 364 ? 15.610 124.661 -45.652 1.00 16.99 ? 420 GLY B O 1 ATOM 2732 N N . SER A 1 365 ? 14.642 125.205 -43.678 1.00 11.36 ? 421 SER B N 1 ATOM 2733 C CA . SER A 1 365 ? 15.852 125.774 -43.105 1.00 3.41 ? 421 SER B CA 1 ATOM 2734 C C . SER A 1 365 ? 16.749 124.686 -42.577 1.00 6.29 ? 421 SER B C 1 ATOM 2735 O O . SER A 1 365 ? 16.274 123.596 -42.274 1.00 10.58 ? 421 SER B O 1 ATOM 2736 C CB . SER A 1 365 ? 15.511 126.722 -41.969 1.00 17.55 ? 421 SER B CB 1 ATOM 2737 O OG . SER A 1 365 ? 15.180 127.993 -42.477 1.00 22.78 ? 421 SER B OG 1 ATOM 2738 N N . ILE A 1 366 ? 18.046 124.973 -42.503 1.00 3.53 ? 422 ILE B N 1 ATOM 2739 C CA . ILE A 1 366 ? 18.957 124.165 -41.710 1.00 10.94 ? 422 ILE B CA 1 ATOM 2740 C C . ILE A 1 366 ? 18.708 124.539 -40.246 1.00 13.15 ? 422 ILE B C 1 ATOM 2741 O O . ILE A 1 366 ? 18.862 125.710 -39.864 1.00 11.77 ? 422 ILE B O 1 ATOM 2742 C CB . ILE A 1 366 ? 20.443 124.452 -42.064 1.00 8.38 ? 422 ILE B CB 1 ATOM 2743 C CG1 . ILE A 1 366 ? 20.697 124.232 -43.549 1.00 8.38 ? 422 ILE B CG1 1 ATOM 2744 C CG2 . ILE A 1 366 ? 21.382 123.554 -41.227 1.00 12.65 ? 422 ILE B CG2 1 ATOM 2745 C CD1 . ILE A 1 366 ? 22.041 124.701 -44.029 1.00 18.32 ? 422 ILE B CD1 1 ATOM 2746 N N . PRO A 1 367 ? 18.298 123.560 -39.424 1.00 14.09 ? 423 PRO B N 1 ATOM 2747 C CA . PRO A 1 367 ? 17.948 123.844 -38.025 1.00 3.75 ? 423 PRO B CA 1 ATOM 2748 C C . PRO A 1 367 ? 19.188 124.255 -37.253 1.00 5.55 ? 423 PRO B C 1 ATOM 2749 O O . PRO A 1 367 ? 20.200 123.565 -37.334 1.00 4.04 ? 423 PRO B O 1 ATOM 2750 C CB . PRO A 1 367 ? 17.433 122.493 -37.512 1.00 5.25 ? 423 PRO B CB 1 ATOM 2751 C CG . PRO A 1 367 ? 18.105 121.491 -38.354 1.00 12.84 ? 423 PRO B CG 1 ATOM 2752 C CD . PRO A 1 367 ? 18.232 122.121 -39.727 1.00 12.54 ? 423 PRO B CD 1 ATOM 2753 N N . LYS A 1 368 ? 19.116 125.337 -36.487 1.00 8.58 ? 424 LYS B N 1 ATOM 2754 C CA . LYS A 1 368 ? 20.311 125.846 -35.826 1.00 5.32 ? 424 LYS B CA 1 ATOM 2755 C C . LYS A 1 368 ? 20.912 124.882 -34.815 1.00 8.86 ? 424 LYS B C 1 ATOM 2756 O O . LYS A 1 368 ? 22.106 124.932 -34.535 1.00 9.87 ? 424 LYS B O 1 ATOM 2757 C CB . LYS A 1 368 ? 19.996 127.150 -35.138 1.00 7.54 ? 424 LYS B CB 1 ATOM 2758 C CG . LYS A 1 368 ? 18.960 127.031 -34.062 1.00 6.12 ? 424 LYS B CG 1 ATOM 2759 C CD . LYS A 1 368 ? 18.677 128.412 -33.514 1.00 12.40 ? 424 LYS B CD 1 ATOM 2760 C CE . LYS A 1 368 ? 17.567 128.398 -32.478 1.00 24.21 ? 424 LYS B CE 1 ATOM 2761 N NZ . LYS A 1 368 ? 17.056 129.785 -32.253 1.00 32.44 ? 424 LYS B NZ 1 ATOM 2762 N N . GLU A 1 369 ? 20.085 123.991 -34.284 1.00 6.77 ? 425 GLU B N 1 ATOM 2763 C CA . GLU A 1 369 ? 20.512 123.089 -33.230 1.00 13.27 ? 425 GLU B CA 1 ATOM 2764 C C . GLU A 1 369 ? 21.629 122.167 -33.694 1.00 15.22 ? 425 GLU B C 1 ATOM 2765 O O . GLU A 1 369 ? 22.474 121.750 -32.920 1.00 23.04 ? 425 GLU B O 1 ATOM 2766 C CB . GLU A 1 369 ? 19.324 122.281 -32.700 1.00 18.77 ? 425 GLU B CB 1 ATOM 2767 C CG . GLU A 1 369 ? 18.304 123.108 -31.897 1.00 21.33 ? 425 GLU B CG 1 ATOM 2768 C CD . GLU A 1 369 ? 17.281 123.846 -32.771 1.00 33.69 ? 425 GLU B CD 1 ATOM 2769 O OE1 . GLU A 1 369 ? 17.276 123.674 -34.014 1.00 32.27 ? 425 GLU B OE1 1 ATOM 2770 O OE2 . GLU A 1 369 ? 16.474 124.613 -32.204 1.00 41.91 ? 425 GLU B OE2 1 ATOM 2771 N N . ILE A 1 370 ? 21.655 121.870 -34.976 1.00 18.51 ? 426 ILE B N 1 ATOM 2772 C CA . ILE A 1 370 ? 22.659 120.955 -35.484 1.00 20.29 ? 426 ILE B CA 1 ATOM 2773 C C . ILE A 1 370 ? 24.060 121.562 -35.290 1.00 20.56 ? 426 ILE B C 1 ATOM 2774 O O . ILE A 1 370 ? 25.064 120.846 -35.223 1.00 14.23 ? 426 ILE B O 1 ATOM 2775 C CB . ILE A 1 370 ? 22.381 120.604 -36.965 1.00 21.78 ? 426 ILE B CB 1 ATOM 2776 C CG1 . ILE A 1 370 ? 22.536 119.110 -37.209 1.00 28.90 ? 426 ILE B CG1 1 ATOM 2777 C CG2 . ILE A 1 370 ? 23.264 121.395 -37.888 1.00 24.43 ? 426 ILE B CG2 1 ATOM 2778 C CD1 . ILE A 1 370 ? 21.297 118.319 -36.848 1.00 31.98 ? 426 ILE B CD1 1 ATOM 2779 N N . PHE A 1 371 ? 24.118 122.886 -35.163 1.00 16.98 ? 427 PHE B N 1 ATOM 2780 C CA . PHE A 1 371 ? 25.401 123.562 -35.067 1.00 19.66 ? 427 PHE B CA 1 ATOM 2781 C C . PHE A 1 371 ? 25.875 123.616 -33.607 1.00 23.60 ? 427 PHE B C 1 ATOM 2782 O O . PHE A 1 371 ? 26.941 124.163 -33.302 1.00 22.99 ? 427 PHE B O 1 ATOM 2783 C CB . PHE A 1 371 ? 25.338 124.959 -35.711 1.00 16.94 ? 427 PHE B CB 1 ATOM 2784 C CG . PHE A 1 371 ? 25.345 124.943 -37.234 1.00 13.95 ? 427 PHE B CG 1 ATOM 2785 C CD1 . PHE A 1 371 ? 26.486 124.564 -37.937 1.00 17.28 ? 427 PHE B CD1 1 ATOM 2786 C CD2 . PHE A 1 371 ? 24.228 125.344 -37.958 1.00 14.84 ? 427 PHE B CD2 1 ATOM 2787 C CE1 . PHE A 1 371 ? 26.519 124.563 -39.335 1.00 9.24 ? 427 PHE B CE1 1 ATOM 2788 C CE2 . PHE A 1 371 ? 24.242 125.350 -39.358 1.00 11.79 ? 427 PHE B CE2 1 ATOM 2789 C CZ . PHE A 1 371 ? 25.394 124.953 -40.045 1.00 13.71 ? 427 PHE B CZ 1 ATOM 2790 N N . GLY A 1 372 ? 25.079 123.036 -32.708 1.00 19.60 ? 428 GLY B N 1 ATOM 2791 C CA . GLY A 1 372 ? 25.459 122.935 -31.315 1.00 6.40 ? 428 GLY B CA 1 ATOM 2792 C C . GLY A 1 372 ? 26.195 121.641 -31.018 1.00 22.65 ? 428 GLY B C 1 ATOM 2793 O O . GLY A 1 372 ? 26.597 121.378 -29.876 1.00 14.64 ? 428 GLY B O 1 ATOM 2794 N N . LEU A 1 373 ? 26.388 120.819 -32.046 1.00 23.02 ? 429 LEU B N 1 ATOM 2795 C CA . LEU A 1 373 ? 27.137 119.575 -31.877 1.00 15.78 ? 429 LEU B CA 1 ATOM 2796 C C . LEU A 1 373 ? 28.636 119.892 -31.757 1.00 16.63 ? 429 LEU B C 1 ATOM 2797 O O . LEU A 1 373 ? 29.215 120.543 -32.627 1.00 25.48 ? 429 LEU B O 1 ATOM 2798 C CB . LEU A 1 373 ? 26.831 118.615 -33.027 1.00 14.21 ? 429 LEU B CB 1 ATOM 2799 C CG . LEU A 1 373 ? 25.357 118.169 -33.092 1.00 15.74 ? 429 LEU B CG 1 ATOM 2800 C CD1 . LEU A 1 373 ? 24.989 117.550 -34.442 1.00 13.74 ? 429 LEU B CD1 1 ATOM 2801 C CD2 . LEU A 1 373 ? 25.002 117.202 -31.951 1.00 9.52 ? 429 LEU B CD2 1 ATOM 2802 N N . ARG A 1 374 ? 29.247 119.477 -30.649 1.00 14.13 ? 430 ARG B N 1 ATOM 2803 C CA . ARG A 1 374 ? 30.603 119.918 -30.325 1.00 16.69 ? 430 ARG B CA 1 ATOM 2804 C C . ARG A 1 374 ? 31.619 119.013 -30.974 1.00 15.13 ? 430 ARG B C 1 ATOM 2805 O O . ARG A 1 374 ? 32.816 119.322 -31.008 1.00 17.62 ? 430 ARG B O 1 ATOM 2806 C CB . ARG A 1 374 ? 30.837 119.931 -28.807 1.00 27.56 ? 430 ARG B CB 1 ATOM 2807 C CG . ARG A 1 374 ? 29.920 120.858 -27.997 1.00 41.57 ? 430 ARG B CG 1 ATOM 2808 C CD . ARG A 1 374 ? 30.151 120.710 -26.475 1.00 56.47 ? 430 ARG B CD 1 ATOM 2809 N NE . ARG A 1 374 ? 31.535 121.002 -26.079 1.00 61.17 ? 430 ARG B NE 1 ATOM 2810 C CZ . ARG A 1 374 ? 32.393 120.101 -25.599 1.00 56.47 ? 430 ARG B CZ 1 ATOM 2811 N NH1 . ARG A 1 374 ? 32.019 118.840 -25.428 1.00 48.63 ? 430 ARG B NH1 1 ATOM 2812 N NH2 . ARG A 1 374 ? 33.628 120.465 -25.279 1.00 59.48 ? 430 ARG B NH2 1 ATOM 2813 N N . ASN A 1 375 ? 31.162 117.846 -31.405 1.00 7.50 ? 431 ASN B N 1 ATOM 2814 C CA . ASN A 1 375 ? 32.045 116.934 -32.115 1.00 12.82 ? 431 ASN B CA 1 ATOM 2815 C C . ASN A 1 375 ? 31.888 116.792 -33.616 1.00 10.64 ? 431 ASN B C 1 ATOM 2816 O O . ASN A 1 375 ? 32.578 115.973 -34.216 1.00 13.26 ? 431 ASN B O 1 ATOM 2817 C CB . ASN A 1 375 ? 32.110 115.574 -31.437 1.00 25.95 ? 431 ASN B CB 1 ATOM 2818 C CG . ASN A 1 375 ? 33.310 115.447 -30.542 1.00 28.15 ? 431 ASN B CG 1 ATOM 2819 O OD1 . ASN A 1 375 ? 33.182 115.352 -29.315 1.00 32.93 ? 431 ASN B OD1 1 ATOM 2820 N ND2 . ASN A 1 375 ? 34.498 115.447 -31.150 1.00 30.00 ? 431 ASN B ND2 1 ATOM 2821 N N . LEU A 1 376 ? 30.985 117.558 -34.226 1.00 9.17 ? 432 LEU B N 1 ATOM 2822 C CA . LEU A 1 376 ? 30.675 117.332 -35.628 1.00 11.59 ? 432 LEU B CA 1 ATOM 2823 C C . LEU A 1 376 ? 31.839 117.887 -36.452 1.00 5.25 ? 432 LEU B C 1 ATOM 2824 O O . LEU A 1 376 ? 32.087 119.092 -36.451 1.00 21.50 ? 432 LEU B O 1 ATOM 2825 C CB . LEU A 1 376 ? 29.396 118.096 -35.969 1.00 13.18 ? 432 LEU B CB 1 ATOM 2826 C CG . LEU A 1 376 ? 28.749 117.989 -37.349 1.00 20.29 ? 432 LEU B CG 1 ATOM 2827 C CD1 . LEU A 1 376 ? 28.376 116.539 -37.681 1.00 3.34 ? 432 LEU B CD1 1 ATOM 2828 C CD2 . LEU A 1 376 ? 27.517 118.888 -37.410 1.00 3.88 ? 432 LEU B CD2 1 ATOM 2829 N N . THR A 1 377 ? 32.576 116.992 -37.112 1.00 10.35 ? 433 THR B N 1 ATOM 2830 C CA . THR A 1 377 ? 33.653 117.373 -38.043 1.00 10.82 ? 433 THR B CA 1 ATOM 2831 C C . THR A 1 377 ? 33.206 117.599 -39.480 1.00 9.17 ? 433 THR B C 1 ATOM 2832 O O . THR A 1 377 ? 33.757 118.450 -40.172 1.00 13.47 ? 433 THR B O 1 ATOM 2833 C CB . THR A 1 377 ? 34.872 116.405 -38.000 1.00 12.74 ? 433 THR B CB 1 ATOM 2834 O OG1 . THR A 1 377 ? 34.449 115.078 -38.310 1.00 21.55 ? 433 THR B OG1 1 ATOM 2835 C CG2 . THR A 1 377 ? 35.477 116.390 -36.635 1.00 9.24 ? 433 THR B CG2 1 ATOM 2836 N N . LYS A 1 378 ? 32.228 116.812 -39.934 1.00 10.38 ? 434 LYS B N 1 ATOM 2837 C CA . LYS A 1 378 ? 31.752 116.877 -41.328 1.00 7.15 ? 434 LYS B CA 1 ATOM 2838 C C . LYS A 1 378 ? 30.257 117.133 -41.412 1.00 3.48 ? 434 LYS B C 1 ATOM 2839 O O . LYS A 1 378 ? 29.455 116.344 -40.895 1.00 8.12 ? 434 LYS B O 1 ATOM 2840 C CB . LYS A 1 378 ? 32.048 115.570 -42.071 1.00 8.58 ? 434 LYS B CB 1 ATOM 2841 C CG . LYS A 1 378 ? 33.509 115.248 -42.211 1.00 14.06 ? 434 LYS B CG 1 ATOM 2842 C CD . LYS A 1 378 ? 33.718 113.893 -42.855 1.00 8.63 ? 434 LYS B CD 1 ATOM 2843 C CE . LYS A 1 378 ? 35.205 113.584 -42.963 1.00 9.81 ? 434 LYS B CE 1 ATOM 2844 N NZ . LYS A 1 378 ? 35.422 112.228 -43.527 1.00 14.94 ? 434 LYS B NZ 1 ATOM 2845 N N . LEU A 1 379 ? 29.883 118.223 -42.073 1.00 3.53 ? 435 LEU B N 1 ATOM 2846 C CA . LEU A 1 379 ? 28.481 118.485 -42.362 1.00 6.22 ? 435 LEU B CA 1 ATOM 2847 C C . LEU A 1 379 ? 28.302 118.660 -43.868 1.00 11.59 ? 435 LEU B C 1 ATOM 2848 O O . LEU A 1 379 ? 28.780 119.636 -44.447 1.00 19.44 ? 435 LEU B O 1 ATOM 2849 C CB . LEU A 1 379 ? 28.009 119.739 -41.617 1.00 3.44 ? 435 LEU B CB 1 ATOM 2850 C CG . LEU A 1 379 ? 26.556 120.137 -41.854 1.00 5.31 ? 435 LEU B CG 1 ATOM 2851 C CD1 . LEU A 1 379 ? 25.656 118.916 -41.698 1.00 8.13 ? 435 LEU B CD1 1 ATOM 2852 C CD2 . LEU A 1 379 ? 26.134 121.192 -40.873 1.00 4.78 ? 435 LEU B CD2 1 ATOM 2853 N N . LEU A 1 380 ? 27.618 117.716 -44.508 1.00 15.37 ? 436 LEU B N 1 ATOM 2854 C CA . LEU A 1 380 ? 27.482 117.748 -45.963 1.00 2.00 ? 436 LEU B CA 1 ATOM 2855 C C . LEU A 1 380 ? 26.027 117.656 -46.324 1.00 6.06 ? 436 LEU B C 1 ATOM 2856 O O . LEU A 1 380 ? 25.398 116.600 -46.178 1.00 5.75 ? 436 LEU B O 1 ATOM 2857 C CB . LEU A 1 380 ? 28.244 116.571 -46.566 1.00 2.00 ? 436 LEU B CB 1 ATOM 2858 C CG . LEU A 1 380 ? 29.680 116.457 -46.029 1.00 15.40 ? 436 LEU B CG 1 ATOM 2859 C CD1 . LEU A 1 380 ? 30.355 115.165 -46.451 1.00 22.43 ? 436 LEU B CD1 1 ATOM 2860 C CD2 . LEU A 1 380 ? 30.508 117.654 -46.470 1.00 14.63 ? 436 LEU B CD2 1 ATOM 2861 N N . LEU A 1 381 ? 25.496 118.811 -46.714 1.00 4.82 ? 437 LEU B N 1 ATOM 2862 C CA . LEU A 1 381 ? 24.120 119.001 -47.177 1.00 5.31 ? 437 LEU B CA 1 ATOM 2863 C C . LEU A 1 381 ? 23.951 119.335 -48.667 1.00 10.81 ? 437 LEU B C 1 ATOM 2864 O O . LEU A 1 381 ? 22.889 119.825 -49.070 1.00 5.00 ? 437 LEU B O 1 ATOM 2865 C CB . LEU A 1 381 ? 23.380 120.003 -46.285 1.00 5.16 ? 437 LEU B CB 1 ATOM 2866 C CG . LEU A 1 381 ? 23.426 119.672 -44.786 1.00 6.06 ? 437 LEU B CG 1 ATOM 2867 C CD1 . LEU A 1 381 ? 22.760 120.761 -43.977 1.00 9.83 ? 437 LEU B CD1 1 ATOM 2868 C CD2 . LEU A 1 381 ? 22.752 118.345 -44.525 1.00 2.00 ? 437 LEU B CD2 1 ATOM 2869 N N . LEU A 1 382 ? 25.019 119.224 -49.454 1.00 9.22 ? 438 LEU B N 1 ATOM 2870 C CA . LEU A 1 382 ? 24.982 119.724 -50.827 1.00 13.59 ? 438 LEU B CA 1 ATOM 2871 C C . LEU A 1 382 ? 23.906 119.098 -51.726 1.00 12.75 ? 438 LEU B C 1 ATOM 2872 O O . LEU A 1 382 ? 23.462 117.981 -51.511 1.00 17.37 ? 438 LEU B O 1 ATOM 2873 C CB . LEU A 1 382 ? 26.364 119.671 -51.509 1.00 14.48 ? 438 LEU B CB 1 ATOM 2874 C CG . LEU A 1 382 ? 26.981 118.315 -51.836 1.00 12.15 ? 438 LEU B CG 1 ATOM 2875 C CD1 . LEU A 1 382 ? 26.636 117.903 -53.258 1.00 2.13 ? 438 LEU B CD1 1 ATOM 2876 C CD2 . LEU A 1 382 ? 28.484 118.336 -51.615 1.00 6.13 ? 438 LEU B CD2 1 ATOM 2877 N N . SER A 1 383 ? 23.489 119.861 -52.727 1.00 8.14 ? 439 SER B N 1 ATOM 2878 C CA . SER A 1 383 ? 22.453 119.449 -53.666 1.00 10.50 ? 439 SER B CA 1 ATOM 2879 C C . SER A 1 383 ? 21.162 118.993 -52.999 1.00 7.15 ? 439 SER B C 1 ATOM 2880 O O . SER A 1 383 ? 20.822 117.812 -52.993 1.00 9.55 ? 439 SER B O 1 ATOM 2881 C CB . SER A 1 383 ? 22.958 118.416 -54.661 1.00 9.20 ? 439 SER B CB 1 ATOM 2882 O OG . SER A 1 383 ? 21.978 118.209 -55.663 1.00 15.09 ? 439 SER B OG 1 ATOM 2883 N N . ASN A 1 384 ? 20.451 119.960 -52.440 1.00 4.68 ? 440 ASN B N 1 ATOM 2884 C CA . ASN A 1 384 ? 19.109 119.745 -51.917 1.00 7.83 ? 440 ASN B CA 1 ATOM 2885 C C . ASN A 1 384 ? 18.250 120.956 -52.322 1.00 8.57 ? 440 ASN B C 1 ATOM 2886 O O . ASN A 1 384 ? 18.600 121.711 -53.227 1.00 6.32 ? 440 ASN B O 1 ATOM 2887 C CB . ASN A 1 384 ? 19.140 119.556 -50.390 1.00 9.57 ? 440 ASN B CB 1 ATOM 2888 C CG . ASN A 1 384 ? 19.511 118.119 -49.967 1.00 12.48 ? 440 ASN B CG 1 ATOM 2889 O OD1 . ASN A 1 384 ? 18.693 117.221 -50.072 1.00 10.75 ? 440 ASN B OD1 1 ATOM 2890 N ND2 . ASN A 1 384 ? 20.728 117.919 -49.463 1.00 2.00 ? 440 ASN B ND2 1 ATOM 2891 N N . ASP A 1 385 ? 17.074 121.079 -51.744 1.00 12.28 ? 441 ASP B N 1 ATOM 2892 C CA . ASP A 1 385 ? 16.265 122.285 -51.885 1.00 8.72 ? 441 ASP B CA 1 ATOM 2893 C C . ASP A 1 385 ? 16.299 123.229 -50.669 1.00 5.11 ? 441 ASP B C 1 ATOM 2894 O O . ASP A 1 385 ? 15.332 123.942 -50.423 1.00 6.70 ? 441 ASP B O 1 ATOM 2895 C CB . ASP A 1 385 ? 14.854 122.015 -52.420 1.00 15.00 ? 441 ASP B CB 1 ATOM 2896 C CG . ASP A 1 385 ? 14.228 123.257 -53.055 1.00 28.52 ? 441 ASP B CG 1 ATOM 2897 O OD1 . ASP A 1 385 ? 14.979 124.065 -53.653 1.00 30.73 ? 441 ASP B OD1 1 ATOM 2898 O OD2 . ASP A 1 385 ? 12.993 123.440 -52.941 1.00 34.65 ? 441 ASP B OD2 1 ATOM 2899 N N . LEU A 1 386 ? 17.307 123.091 -49.815 1.00 5.48 ? 442 LEU B N 1 ATOM 2900 C CA . LEU A 1 386 ? 17.393 123.876 -48.569 1.00 2.02 ? 442 LEU B CA 1 ATOM 2901 C C . LEU A 1 386 ? 17.331 125.377 -48.808 1.00 2.37 ? 442 LEU B C 1 ATOM 2902 O O . LEU A 1 386 ? 17.774 125.858 -49.845 1.00 7.07 ? 442 LEU B O 1 ATOM 2903 C CB . LEU A 1 386 ? 18.686 123.536 -47.818 1.00 2.00 ? 442 LEU B CB 1 ATOM 2904 C CG . LEU A 1 386 ? 18.818 122.129 -47.233 1.00 2.00 ? 442 LEU B CG 1 ATOM 2905 C CD1 . LEU A 1 386 ? 20.223 121.906 -46.710 1.00 2.00 ? 442 LEU B CD1 1 ATOM 2906 C CD2 . LEU A 1 386 ? 17.784 121.907 -46.128 1.00 2.00 ? 442 LEU B CD2 1 ATOM 2907 N N . SER A 1 387 ? 16.766 126.119 -47.863 1.00 2.72 ? 443 SER B N 1 ATOM 2908 C CA . SER A 1 387 ? 16.764 127.587 -47.941 1.00 7.73 ? 443 SER B CA 1 ATOM 2909 C C . SER A 1 387 ? 16.781 128.263 -46.574 1.00 10.40 ? 443 SER B C 1 ATOM 2910 O O . SER A 1 387 ? 16.983 127.628 -45.543 1.00 12.23 ? 443 SER B O 1 ATOM 2911 C CB . SER A 1 387 ? 15.574 128.107 -48.749 1.00 3.22 ? 443 SER B CB 1 ATOM 2912 O OG . SER A 1 387 ? 14.353 127.805 -48.105 1.00 4.83 ? 443 SER B OG 1 ATOM 2913 N N . GLY A 1 388 ? 16.562 129.569 -46.570 1.00 12.46 ? 444 GLY B N 1 ATOM 2914 C CA . GLY A 1 388 ? 16.659 130.316 -45.336 1.00 7.00 ? 444 GLY B CA 1 ATOM 2915 C C . GLY A 1 388 ? 18.089 130.744 -45.090 1.00 15.03 ? 444 GLY B C 1 ATOM 2916 O O . GLY A 1 388 ? 18.955 130.621 -45.978 1.00 17.86 ? 444 GLY B O 1 ATOM 2917 N N . PHE A 1 389 ? 18.330 131.269 -43.891 1.00 13.59 ? 445 PHE B N 1 ATOM 2918 C CA . PHE A 1 389 ? 19.639 131.780 -43.505 1.00 5.76 ? 445 PHE B CA 1 ATOM 2919 C C . PHE A 1 389 ? 20.571 130.688 -43.046 1.00 10.00 ? 445 PHE B C 1 ATOM 2920 O O . PHE A 1 389 ? 20.129 129.632 -42.607 1.00 19.49 ? 445 PHE B O 1 ATOM 2921 C CB . PHE A 1 389 ? 19.501 132.813 -42.389 1.00 6.44 ? 445 PHE B CB 1 ATOM 2922 C CG . PHE A 1 389 ? 18.717 134.033 -42.781 1.00 6.79 ? 445 PHE B CG 1 ATOM 2923 C CD1 . PHE A 1 389 ? 18.805 134.552 -44.068 1.00 17.97 ? 445 PHE B CD1 1 ATOM 2924 C CD2 . PHE A 1 389 ? 17.870 134.654 -41.865 1.00 15.95 ? 445 PHE B CD2 1 ATOM 2925 C CE1 . PHE A 1 389 ? 18.072 135.686 -44.436 1.00 22.38 ? 445 PHE B CE1 1 ATOM 2926 C CE2 . PHE A 1 389 ? 17.133 135.779 -42.213 1.00 7.54 ? 445 PHE B CE2 1 ATOM 2927 C CZ . PHE A 1 389 ? 17.240 136.303 -43.504 1.00 24.55 ? 445 PHE B CZ 1 ATOM 2928 N N . ILE A 1 390 ? 21.867 130.947 -43.153 1.00 10.61 ? 446 ILE B N 1 ATOM 2929 C CA . ILE A 1 390 ? 22.835 130.222 -42.347 1.00 12.78 ? 446 ILE B CA 1 ATOM 2930 C C . ILE A 1 390 ? 22.726 130.819 -40.950 1.00 13.64 ? 446 ILE B C 1 ATOM 2931 O O . ILE A 1 390 ? 22.876 132.022 -40.770 1.00 24.21 ? 446 ILE B O 1 ATOM 2932 C CB . ILE A 1 390 ? 24.268 130.352 -42.886 1.00 6.12 ? 446 ILE B CB 1 ATOM 2933 C CG1 . ILE A 1 390 ? 24.336 129.835 -44.327 1.00 5.61 ? 446 ILE B CG1 1 ATOM 2934 C CG2 . ILE A 1 390 ? 25.226 129.534 -42.047 1.00 7.08 ? 446 ILE B CG2 1 ATOM 2935 C CD1 . ILE A 1 390 ? 25.681 129.999 -44.977 1.00 5.86 ? 446 ILE B CD1 1 ATOM 2936 N N . PRO A 1 391 ? 22.412 129.980 -39.961 1.00 11.12 ? 447 PRO B N 1 ATOM 2937 C CA . PRO A 1 391 ? 22.187 130.483 -38.601 1.00 6.79 ? 447 PRO B CA 1 ATOM 2938 C C . PRO A 1 391 ? 23.491 130.965 -38.015 1.00 14.66 ? 447 PRO B C 1 ATOM 2939 O O . PRO A 1 391 ? 24.531 130.364 -38.278 1.00 12.54 ? 447 PRO B O 1 ATOM 2940 C CB . PRO A 1 391 ? 21.693 129.242 -37.832 1.00 6.38 ? 447 PRO B CB 1 ATOM 2941 C CG . PRO A 1 391 ? 21.284 128.247 -38.891 1.00 11.56 ? 447 PRO B CG 1 ATOM 2942 C CD . PRO A 1 391 ? 22.153 128.534 -40.086 1.00 10.29 ? 447 PRO B CD 1 ATOM 2943 N N . PRO A 1 392 ? 23.443 132.039 -37.222 1.00 23.16 ? 448 PRO B N 1 ATOM 2944 C CA . PRO A 1 392 ? 24.619 132.538 -36.478 1.00 27.00 ? 448 PRO B CA 1 ATOM 2945 C C . PRO A 1 392 ? 25.225 131.464 -35.563 1.00 15.86 ? 448 PRO B C 1 ATOM 2946 O O . PRO A 1 392 ? 26.436 131.407 -35.318 1.00 30.70 ? 448 PRO B O 1 ATOM 2947 C CB . PRO A 1 392 ? 24.060 133.719 -35.667 1.00 29.49 ? 448 PRO B CB 1 ATOM 2948 C CG . PRO A 1 392 ? 22.544 133.563 -35.711 1.00 26.96 ? 448 PRO B CG 1 ATOM 2949 C CD . PRO A 1 392 ? 22.235 132.850 -36.994 1.00 22.40 ? 448 PRO B CD 1 ATOM 2950 N N . ASP A 1 393 ? 24.384 130.536 -35.136 1.00 17.94 ? 449 ASP B N 1 ATOM 2951 C CA . ASP A 1 393 ? 24.839 129.421 -34.307 1.00 12.63 ? 449 ASP B CA 1 ATOM 2952 C C . ASP A 1 393 ? 25.922 128.589 -34.967 1.00 9.07 ? 449 ASP B C 1 ATOM 2953 O O . ASP A 1 393 ? 26.507 127.739 -34.314 1.00 10.36 ? 449 ASP B O 1 ATOM 2954 C CB . ASP A 1 393 ? 23.677 128.504 -33.980 1.00 10.75 ? 449 ASP B CB 1 ATOM 2955 C CG . ASP A 1 393 ? 22.475 129.263 -33.533 1.00 21.22 ? 449 ASP B CG 1 ATOM 2956 O OD1 . ASP A 1 393 ? 21.894 129.954 -34.411 1.00 19.95 ? 449 ASP B OD1 1 ATOM 2957 O OD2 . ASP A 1 393 ? 22.138 129.182 -32.313 1.00 16.21 ? 449 ASP B OD2 1 ATOM 2958 N N . ILE A 1 394 ? 26.163 128.807 -36.259 1.00 7.55 ? 450 ILE B N 1 ATOM 2959 C CA . ILE A 1 394 ? 27.225 128.096 -36.953 1.00 7.35 ? 450 ILE B CA 1 ATOM 2960 C C . ILE A 1 394 ? 28.534 128.197 -36.157 1.00 16.29 ? 450 ILE B C 1 ATOM 2961 O O . ILE A 1 394 ? 29.308 127.237 -36.110 1.00 22.99 ? 450 ILE B O 1 ATOM 2962 C CB . ILE A 1 394 ? 27.382 128.575 -38.431 1.00 8.65 ? 450 ILE B CB 1 ATOM 2963 C CG1 . ILE A 1 394 ? 28.439 127.761 -39.177 1.00 14.45 ? 450 ILE B CG1 1 ATOM 2964 C CG2 . ILE A 1 394 ? 27.711 130.050 -38.511 1.00 7.90 ? 450 ILE B CG2 1 ATOM 2965 C CD1 . ILE A 1 394 ? 28.373 127.930 -40.710 1.00 14.86 ? 450 ILE B CD1 1 ATOM 2966 N N . GLY A 1 395 ? 28.749 129.324 -35.477 1.00 14.04 ? 451 GLY B N 1 ATOM 2967 C CA . GLY A 1 395 ? 29.965 129.484 -34.679 1.00 17.58 ? 451 GLY B CA 1 ATOM 2968 C C . GLY A 1 395 ? 30.093 128.649 -33.401 1.00 19.28 ? 451 GLY B C 1 ATOM 2969 O O . GLY A 1 395 ? 31.168 128.571 -32.813 1.00 21.25 ? 451 GLY B O 1 ATOM 2970 N N . ASN A 1 396 ? 28.994 128.046 -32.958 1.00 17.58 ? 452 ASN B N 1 ATOM 2971 C CA . ASN A 1 396 ? 28.992 127.150 -31.804 1.00 18.07 ? 452 ASN B CA 1 ATOM 2972 C C . ASN A 1 396 ? 29.612 125.784 -32.116 1.00 18.63 ? 452 ASN B C 1 ATOM 2973 O O . ASN A 1 396 ? 29.866 125.011 -31.198 1.00 21.92 ? 452 ASN B O 1 ATOM 2974 C CB . ASN A 1 396 ? 27.555 126.888 -31.313 1.00 8.52 ? 452 ASN B CB 1 ATOM 2975 C CG . ASN A 1 396 ? 26.890 128.111 -30.694 1.00 10.93 ? 452 ASN B CG 1 ATOM 2976 O OD1 . ASN A 1 396 ? 27.164 129.247 -31.077 1.00 14.06 ? 452 ASN B OD1 1 ATOM 2977 N ND2 . ASN A 1 396 ? 26.006 127.868 -29.716 1.00 12.96 ? 452 ASN B ND2 1 ATOM 2978 N N . CYS A 1 397 ? 29.851 125.479 -33.394 1.00 18.20 ? 453 CYS B N 1 ATOM 2979 C CA . CYS A 1 397 ? 30.119 124.096 -33.791 1.00 17.06 ? 453 CYS B CA 1 ATOM 2980 C C . CYS A 1 397 ? 31.615 123.984 -33.900 1.00 22.08 ? 453 CYS B C 1 ATOM 2981 O O . CYS A 1 397 ? 32.213 124.075 -34.996 1.00 14.66 ? 453 CYS B O 1 ATOM 2982 C CB . CYS A 1 397 ? 29.492 123.854 -35.181 1.00 10.70 ? 453 CYS B CB 1 ATOM 2983 S SG . CYS A 1 397 ? 29.363 122.130 -35.788 1.00 19.22 ? 453 CYS B SG 1 ATOM 2984 N N . THR A 1 398 ? 32.190 123.574 -32.784 1.00 19.60 ? 454 THR B N 1 ATOM 2985 C CA . THR A 1 398 ? 33.547 123.981 -32.474 1.00 23.06 ? 454 THR B CA 1 ATOM 2986 C C . THR A 1 398 ? 34.570 123.189 -33.263 1.00 19.58 ? 454 THR B C 1 ATOM 2987 O O . THR A 1 398 ? 35.623 123.694 -33.606 1.00 9.45 ? 454 THR B O 1 ATOM 2988 C CB . THR A 1 398 ? 33.789 123.930 -30.945 1.00 24.01 ? 454 THR B CB 1 ATOM 2989 O OG1 . THR A 1 398 ? 33.278 125.137 -30.366 1.00 29.55 ? 454 THR B OG1 1 ATOM 2990 C CG2 . THR A 1 398 ? 35.274 123.810 -30.606 1.00 18.97 ? 454 THR B CG2 1 ATOM 2991 N N . ASN A 1 399 ? 34.244 121.936 -33.537 1.00 14.17 ? 455 ASN B N 1 ATOM 2992 C CA . ASN A 1 399 ? 35.153 121.059 -34.253 1.00 9.58 ? 455 ASN B CA 1 ATOM 2993 C C . ASN A 1 399 ? 34.885 120.952 -35.751 1.00 16.11 ? 455 ASN B C 1 ATOM 2994 O O . ASN A 1 399 ? 35.467 120.088 -36.400 1.00 10.62 ? 455 ASN B O 1 ATOM 2995 C CB . ASN A 1 399 ? 35.211 119.671 -33.601 1.00 9.20 ? 455 ASN B CB 1 ATOM 2996 C CG . ASN A 1 399 ? 36.118 119.645 -32.374 1.00 24.54 ? 455 ASN B CG 1 ATOM 2997 O OD1 . ASN A 1 399 ? 37.340 119.761 -32.494 1.00 30.17 ? 455 ASN B OD1 1 ATOM 2998 N ND2 . ASN A 1 399 ? 35.522 119.510 -31.190 1.00 15.97 ? 455 ASN B ND2 1 ATOM 2999 N N . LEU A 1 400 ? 33.973 121.770 -36.289 1.00 7.41 ? 456 LEU B N 1 ATOM 3000 C CA . LEU A 1 400 ? 33.681 121.702 -37.726 1.00 6.94 ? 456 LEU B CA 1 ATOM 3001 C C . LEU A 1 400 ? 34.938 121.766 -38.585 1.00 7.33 ? 456 LEU B C 1 ATOM 3002 O O . LEU A 1 400 ? 35.734 122.683 -38.480 1.00 13.68 ? 456 LEU B O 1 ATOM 3003 C CB . LEU A 1 400 ? 32.744 122.827 -38.152 1.00 6.86 ? 456 LEU B CB 1 ATOM 3004 C CG . LEU A 1 400 ? 31.976 122.500 -39.426 1.00 12.29 ? 456 LEU B CG 1 ATOM 3005 C CD1 . LEU A 1 400 ? 31.341 121.090 -39.350 1.00 5.47 ? 456 LEU B CD1 1 ATOM 3006 C CD2 . LEU A 1 400 ? 30.936 123.566 -39.693 1.00 6.10 ? 456 LEU B CD2 1 ATOM 3007 N N . TYR A 1 401 ? 35.076 120.791 -39.467 1.00 20.02 ? 457 TYR B N 1 ATOM 3008 C CA . TYR A 1 401 ? 36.248 120.658 -40.328 1.00 16.07 ? 457 TYR B CA 1 ATOM 3009 C C . TYR A 1 401 ? 35.892 120.874 -41.803 1.00 16.70 ? 457 TYR B C 1 ATOM 3010 O O . TYR A 1 401 ? 36.442 121.755 -42.468 1.00 24.23 ? 457 TYR B O 1 ATOM 3011 C CB . TYR A 1 401 ? 36.879 119.279 -40.130 1.00 14.70 ? 457 TYR B CB 1 ATOM 3012 C CG . TYR A 1 401 ? 38.187 119.108 -40.843 1.00 15.73 ? 457 TYR B CG 1 ATOM 3013 C CD1 . TYR A 1 401 ? 39.371 119.572 -40.276 1.00 17.02 ? 457 TYR B CD1 1 ATOM 3014 C CD2 . TYR A 1 401 ? 38.246 118.492 -42.078 1.00 7.41 ? 457 TYR B CD2 1 ATOM 3015 C CE1 . TYR A 1 401 ? 40.586 119.420 -40.930 1.00 13.15 ? 457 TYR B CE1 1 ATOM 3016 C CE2 . TYR A 1 401 ? 39.448 118.347 -42.735 1.00 11.54 ? 457 TYR B CE2 1 ATOM 3017 C CZ . TYR A 1 401 ? 40.610 118.812 -42.159 1.00 12.05 ? 457 TYR B CZ 1 ATOM 3018 O OH . TYR A 1 401 ? 41.796 118.654 -42.810 1.00 20.02 ? 457 TYR B OH 1 ATOM 3019 N N . ARG A 1 402 ? 35.001 120.028 -42.315 1.00 11.19 ? 458 ARG B N 1 ATOM 3020 C CA . ARG A 1 402 ? 34.527 120.121 -43.694 1.00 5.73 ? 458 ARG B CA 1 ATOM 3021 C C . ARG A 1 402 ? 33.026 120.474 -43.737 1.00 8.92 ? 458 ARG B C 1 ATOM 3022 O O . ARG A 1 402 ? 32.176 119.758 -43.179 1.00 10.53 ? 458 ARG B O 1 ATOM 3023 C CB . ARG A 1 402 ? 34.827 118.801 -44.408 1.00 6.13 ? 458 ARG B CB 1 ATOM 3024 C CG . ARG A 1 402 ? 34.351 118.670 -45.850 1.00 4.98 ? 458 ARG B CG 1 ATOM 3025 C CD . ARG A 1 402 ? 34.715 117.268 -46.353 1.00 9.95 ? 458 ARG B CD 1 ATOM 3026 N NE . ARG A 1 402 ? 34.438 117.081 -47.769 1.00 14.49 ? 458 ARG B NE 1 ATOM 3027 C CZ . ARG A 1 402 ? 35.197 117.567 -48.746 1.00 15.60 ? 458 ARG B CZ 1 ATOM 3028 N NH1 . ARG A 1 402 ? 34.857 117.352 -50.011 1.00 12.08 ? 458 ARG B NH1 1 ATOM 3029 N NH2 . ARG A 1 402 ? 36.288 118.275 -48.453 1.00 11.93 ? 458 ARG B NH2 1 ATOM 3030 N N . LEU A 1 403 ? 32.711 121.601 -44.369 1.00 6.40 ? 459 LEU B N 1 ATOM 3031 C CA . LEU A 1 403 ? 31.335 122.077 -44.467 1.00 9.00 ? 459 LEU B CA 1 ATOM 3032 C C . LEU A 1 403 ? 30.915 122.252 -45.931 1.00 16.18 ? 459 LEU B C 1 ATOM 3033 O O . LEU A 1 403 ? 31.502 123.062 -46.657 1.00 20.34 ? 459 LEU B O 1 ATOM 3034 C CB . LEU A 1 403 ? 31.201 123.419 -43.759 1.00 5.35 ? 459 LEU B CB 1 ATOM 3035 C CG . LEU A 1 403 ? 29.838 124.113 -43.962 1.00 16.21 ? 459 LEU B CG 1 ATOM 3036 C CD1 . LEU A 1 403 ? 28.689 123.298 -43.371 1.00 4.51 ? 459 LEU B CD1 1 ATOM 3037 C CD2 . LEU A 1 403 ? 29.835 125.529 -43.385 1.00 10.42 ? 459 LEU B CD2 1 ATOM 3038 N N . ARG A 1 404 ? 29.905 121.509 -46.378 1.00 13.90 ? 460 ARG B N 1 ATOM 3039 C CA . ARG A 1 404 ? 29.426 121.718 -47.738 1.00 14.61 ? 460 ARG B CA 1 ATOM 3040 C C . ARG A 1 404 ? 27.928 121.947 -47.781 1.00 17.05 ? 460 ARG B C 1 ATOM 3041 O O . ARG A 1 404 ? 27.138 121.041 -47.470 1.00 11.89 ? 460 ARG B O 1 ATOM 3042 C CB . ARG A 1 404 ? 29.815 120.549 -48.624 1.00 10.84 ? 460 ARG B CB 1 ATOM 3043 C CG . ARG A 1 404 ? 31.317 120.323 -48.688 1.00 8.80 ? 460 ARG B CG 1 ATOM 3044 C CD . ARG A 1 404 ? 31.697 119.414 -49.827 1.00 3.54 ? 460 ARG B CD 1 ATOM 3045 N NE . ARG A 1 404 ? 31.548 120.127 -51.088 1.00 27.26 ? 460 ARG B NE 1 ATOM 3046 C CZ . ARG A 1 404 ? 31.904 119.657 -52.279 1.00 20.31 ? 460 ARG B CZ 1 ATOM 3047 N NH1 . ARG A 1 404 ? 32.444 118.447 -52.401 1.00 3.45 ? 460 ARG B NH1 1 ATOM 3048 N NH2 . ARG A 1 404 ? 31.722 120.419 -53.346 1.00 7.10 ? 460 ARG B NH2 1 ATOM 3049 N N . LEU A 1 405 ? 27.563 123.193 -48.096 1.00 12.30 ? 461 LEU B N 1 ATOM 3050 C CA . LEU A 1 405 ? 26.164 123.610 -48.276 1.00 9.05 ? 461 LEU B CA 1 ATOM 3051 C C . LEU A 1 405 ? 25.752 123.825 -49.730 1.00 3.78 ? 461 LEU B C 1 ATOM 3052 O O . LEU A 1 405 ? 24.656 124.278 -50.016 1.00 9.74 ? 461 LEU B O 1 ATOM 3053 C CB . LEU A 1 405 ? 25.843 124.826 -47.416 1.00 3.48 ? 461 LEU B CB 1 ATOM 3054 C CG . LEU A 1 405 ? 26.259 124.604 -45.959 1.00 12.57 ? 461 LEU B CG 1 ATOM 3055 C CD1 . LEU A 1 405 ? 25.779 125.738 -45.059 1.00 4.22 ? 461 LEU B CD1 1 ATOM 3056 C CD2 . LEU A 1 405 ? 25.763 123.241 -45.438 1.00 3.25 ? 461 LEU B CD2 1 ATOM 3057 N N . ASN A 1 406 ? 26.659 123.537 -50.646 1.00 5.09 ? 462 ASN B N 1 ATOM 3058 C CA . ASN A 1 406 ? 26.522 124.000 -52.019 1.00 5.47 ? 462 ASN B CA 1 ATOM 3059 C C . ASN A 1 406 ? 25.391 123.337 -52.827 1.00 10.69 ? 462 ASN B C 1 ATOM 3060 O O . ASN A 1 406 ? 25.055 122.180 -52.609 1.00 11.74 ? 462 ASN B O 1 ATOM 3061 C CB . ASN A 1 406 ? 27.880 123.925 -52.738 1.00 3.05 ? 462 ASN B CB 1 ATOM 3062 C CG . ASN A 1 406 ? 28.443 122.521 -52.780 1.00 15.22 ? 462 ASN B CG 1 ATOM 3063 O OD1 . ASN A 1 406 ? 28.805 121.957 -51.752 1.00 16.25 ? 462 ASN B OD1 1 ATOM 3064 N ND2 . ASN A 1 406 ? 28.549 121.956 -53.981 1.00 11.54 ? 462 ASN B ND2 1 ATOM 3065 N N . GLY A 1 407 ? 24.807 124.077 -53.768 1.00 8.82 ? 463 GLY B N 1 ATOM 3066 C CA . GLY A 1 407 ? 23.707 123.558 -54.559 1.00 6.47 ? 463 GLY B CA 1 ATOM 3067 C C . GLY A 1 407 ? 22.393 123.561 -53.812 1.00 12.41 ? 463 GLY B C 1 ATOM 3068 O O . GLY A 1 407 ? 21.651 122.567 -53.809 1.00 15.33 ? 463 GLY B O 1 ATOM 3069 N N . ASN A 1 408 ? 22.107 124.689 -53.169 1.00 7.58 ? 464 ASN B N 1 ATOM 3070 C CA . ASN A 1 408 ? 20.839 124.895 -52.473 1.00 6.03 ? 464 ASN B CA 1 ATOM 3071 C C . ASN A 1 408 ? 20.271 126.284 -52.804 1.00 16.23 ? 464 ASN B C 1 ATOM 3072 O O . ASN A 1 408 ? 20.701 126.930 -53.764 1.00 21.56 ? 464 ASN B O 1 ATOM 3073 C CB . ASN A 1 408 ? 21.015 124.734 -50.969 1.00 8.87 ? 464 ASN B CB 1 ATOM 3074 C CG . ASN A 1 408 ? 21.139 123.290 -50.550 1.00 15.04 ? 464 ASN B CG 1 ATOM 3075 O OD1 . ASN A 1 408 ? 20.161 122.553 -50.601 1.00 19.03 ? 464 ASN B OD1 1 ATOM 3076 N ND2 . ASN A 1 408 ? 22.341 122.874 -50.121 1.00 11.48 ? 464 ASN B ND2 1 ATOM 3077 N N . ARG A 1 409 ? 19.240 126.680 -52.076 1.00 2.25 ? 465 ARG B N 1 ATOM 3078 C CA . ARG A 1 409 ? 18.667 128.034 -52.115 1.00 4.90 ? 465 ARG B CA 1 ATOM 3079 C C . ARG A 1 409 ? 19.016 128.995 -50.978 1.00 13.96 ? 465 ARG B C 1 ATOM 3080 O O . ARG A 1 409 ? 18.225 129.897 -50.694 1.00 21.76 ? 465 ARG B O 1 ATOM 3081 C CB . ARG A 1 409 ? 17.164 128.022 -52.373 1.00 10.25 ? 465 ARG B CB 1 ATOM 3082 C CG . ARG A 1 409 ? 16.827 127.836 -53.822 1.00 5.51 ? 465 ARG B CG 1 ATOM 3083 C CD . ARG A 1 409 ? 15.338 128.051 -54.067 1.00 14.54 ? 465 ARG B CD 1 ATOM 3084 N NE . ARG A 1 409 ? 14.467 127.004 -53.533 1.00 15.91 ? 465 ARG B NE 1 ATOM 3085 C CZ . ARG A 1 409 ? 13.552 127.194 -52.576 1.00 18.04 ? 465 ARG B CZ 1 ATOM 3086 N NH1 . ARG A 1 409 ? 13.390 128.392 -52.019 1.00 13.60 ? 465 ARG B NH1 1 ATOM 3087 N NH2 . ARG A 1 409 ? 12.792 126.177 -52.169 1.00 12.41 ? 465 ARG B NH2 1 ATOM 3088 N N . LEU A 1 410 ? 20.070 128.715 -50.215 1.00 10.70 ? 466 LEU B N 1 ATOM 3089 C CA . LEU A 1 410 ? 20.391 129.544 -49.037 1.00 7.05 ? 466 LEU B CA 1 ATOM 3090 C C . LEU A 1 410 ? 20.417 131.046 -49.332 1.00 12.02 ? 466 LEU B C 1 ATOM 3091 O O . LEU A 1 410 ? 20.960 131.470 -50.357 1.00 8.82 ? 466 LEU B O 1 ATOM 3092 C CB . LEU A 1 410 ? 21.709 129.108 -48.418 1.00 4.00 ? 466 LEU B CB 1 ATOM 3093 C CG . LEU A 1 410 ? 21.737 127.631 -48.080 1.00 3.49 ? 466 LEU B CG 1 ATOM 3094 C CD1 . LEU A 1 410 ? 23.124 127.247 -47.641 1.00 11.56 ? 466 LEU B CD1 1 ATOM 3095 C CD2 . LEU A 1 410 ? 20.699 127.284 -47.007 1.00 3.39 ? 466 LEU B CD2 1 ATOM 3096 N N . ALA A 1 411 ? 19.813 131.837 -48.438 1.00 17.66 ? 467 ALA B N 1 ATOM 3097 C CA . ALA A 1 411 ? 19.689 133.295 -48.615 1.00 13.56 ? 467 ALA B CA 1 ATOM 3098 C C . ALA A 1 411 ? 20.357 134.066 -47.475 1.00 8.85 ? 467 ALA B C 1 ATOM 3099 O O . ALA A 1 411 ? 20.887 133.461 -46.538 1.00 10.98 ? 467 ALA B O 1 ATOM 3100 C CB . ALA A 1 411 ? 18.224 133.696 -48.727 1.00 5.33 ? 467 ALA B CB 1 ATOM 3101 N N . GLY A 1 412 ? 20.326 135.393 -47.543 1.00 6.56 ? 468 GLY B N 1 ATOM 3102 C CA . GLY A 1 412 ? 20.966 136.216 -46.525 1.00 7.24 ? 468 GLY B CA 1 ATOM 3103 C C . GLY A 1 412 ? 22.485 136.273 -46.648 1.00 11.84 ? 468 GLY B C 1 ATOM 3104 O O . GLY A 1 412 ? 23.049 135.900 -47.668 1.00 13.48 ? 468 GLY B O 1 ATOM 3105 N N . SER A 1 413 ? 23.168 136.715 -45.601 1.00 9.65 ? 469 SER B N 1 ATOM 3106 C CA . SER A 1 413 ? 24.619 136.844 -45.687 1.00 10.86 ? 469 SER B CA 1 ATOM 3107 C C . SER A 1 413 ? 25.382 135.842 -44.816 1.00 13.85 ? 469 SER B C 1 ATOM 3108 O O . SER A 1 413 ? 24.828 135.255 -43.877 1.00 15.20 ? 469 SER B O 1 ATOM 3109 C CB . SER A 1 413 ? 25.054 138.282 -45.409 1.00 9.63 ? 469 SER B CB 1 ATOM 3110 O OG . SER A 1 413 ? 24.310 138.820 -44.344 1.00 14.01 ? 469 SER B OG 1 ATOM 3111 N N . ILE A 1 414 ? 26.630 135.582 -45.185 1.00 11.70 ? 470 ILE B N 1 ATOM 3112 C CA . ILE A 1 414 ? 27.433 134.621 -44.452 1.00 8.40 ? 470 ILE B CA 1 ATOM 3113 C C . ILE A 1 414 ? 27.697 135.220 -43.081 1.00 10.81 ? 470 ILE B C 1 ATOM 3114 O O . ILE A 1 414 ? 28.322 136.277 -42.974 1.00 9.73 ? 470 ILE B O 1 ATOM 3115 C CB . ILE A 1 414 ? 28.763 134.339 -45.167 1.00 16.65 ? 470 ILE B CB 1 ATOM 3116 C CG1 . ILE A 1 414 ? 28.510 133.841 -46.595 1.00 17.90 ? 470 ILE B CG1 1 ATOM 3117 C CG2 . ILE A 1 414 ? 29.603 133.336 -44.375 1.00 10.01 ? 470 ILE B CG2 1 ATOM 3118 C CD1 . ILE A 1 414 ? 29.752 133.785 -47.438 1.00 8.13 ? 470 ILE B CD1 1 ATOM 3119 N N . PRO A 1 415 ? 27.196 134.565 -42.025 1.00 12.89 ? 471 PRO B N 1 ATOM 3120 C CA . PRO A 1 415 ? 27.255 135.149 -40.683 1.00 10.38 ? 471 PRO B CA 1 ATOM 3121 C C . PRO A 1 415 ? 28.692 135.307 -40.187 1.00 13.29 ? 471 PRO B C 1 ATOM 3122 O O . PRO A 1 415 ? 29.535 134.466 -40.488 1.00 17.31 ? 471 PRO B O 1 ATOM 3123 C CB . PRO A 1 415 ? 26.483 134.134 -39.834 1.00 13.27 ? 471 PRO B CB 1 ATOM 3124 C CG . PRO A 1 415 ? 26.528 132.869 -40.606 1.00 12.03 ? 471 PRO B CG 1 ATOM 3125 C CD . PRO A 1 415 ? 26.496 133.272 -42.035 1.00 12.18 ? 471 PRO B CD 1 ATOM 3126 N N . SER A 1 416 ? 28.968 136.383 -39.456 1.00 14.37 ? 472 SER B N 1 ATOM 3127 C CA . SER A 1 416 ? 30.314 136.663 -38.954 1.00 15.45 ? 472 SER B CA 1 ATOM 3128 C C . SER A 1 416 ? 30.837 135.566 -38.045 1.00 19.54 ? 472 SER B C 1 ATOM 3129 O O . SER A 1 416 ? 32.046 135.362 -37.922 1.00 24.99 ? 472 SER B O 1 ATOM 3130 C CB . SER A 1 416 ? 30.324 137.970 -38.168 1.00 19.79 ? 472 SER B CB 1 ATOM 3131 O OG . SER A 1 416 ? 30.309 139.080 -39.042 1.00 40.35 ? 472 SER B OG 1 ATOM 3132 N N . GLU A 1 417 ? 29.927 134.859 -37.391 1.00 16.76 ? 473 GLU B N 1 ATOM 3133 C CA . GLU A 1 417 ? 30.353 133.930 -36.354 1.00 16.97 ? 473 GLU B CA 1 ATOM 3134 C C . GLU A 1 417 ? 31.038 132.698 -36.937 1.00 19.04 ? 473 GLU B C 1 ATOM 3135 O O . GLU A 1 417 ? 31.601 131.899 -36.198 1.00 20.67 ? 473 GLU B O 1 ATOM 3136 C CB . GLU A 1 417 ? 29.205 133.556 -35.413 1.00 14.05 ? 473 GLU B CB 1 ATOM 3137 C CG . GLU A 1 417 ? 27.848 133.891 -35.965 1.00 30.01 ? 473 GLU B CG 1 ATOM 3138 C CD . GLU A 1 417 ? 27.459 135.331 -35.776 1.00 32.91 ? 473 GLU B CD 1 ATOM 3139 O OE1 . GLU A 1 417 ? 27.527 136.090 -36.760 1.00 43.45 ? 473 GLU B OE1 1 ATOM 3140 O OE2 . GLU A 1 417 ? 27.081 135.705 -34.652 1.00 34.09 ? 473 GLU B OE2 1 ATOM 3141 N N . ILE A 1 418 ? 31.030 132.565 -38.265 1.00 17.33 ? 474 ILE B N 1 ATOM 3142 C CA . ILE A 1 418 ? 31.785 131.496 -38.898 1.00 13.63 ? 474 ILE B CA 1 ATOM 3143 C C . ILE A 1 418 ? 33.258 131.665 -38.528 1.00 21.47 ? 474 ILE B C 1 ATOM 3144 O O . ILE A 1 418 ? 34.019 130.692 -38.474 1.00 24.26 ? 474 ILE B O 1 ATOM 3145 C CB . ILE A 1 418 ? 31.584 131.451 -40.440 1.00 17.76 ? 474 ILE B CB 1 ATOM 3146 C CG1 . ILE A 1 418 ? 32.233 130.199 -41.038 1.00 14.58 ? 474 ILE B CG1 1 ATOM 3147 C CG2 . ILE A 1 418 ? 32.141 132.698 -41.105 1.00 19.43 ? 474 ILE B CG2 1 ATOM 3148 C CD1 . ILE A 1 418 ? 31.930 130.012 -42.500 1.00 18.14 ? 474 ILE B CD1 1 ATOM 3149 N N . GLY A 1 419 ? 33.639 132.902 -38.224 1.00 11.16 ? 475 GLY B N 1 ATOM 3150 C CA . GLY A 1 419 ? 34.999 133.200 -37.827 1.00 20.93 ? 475 GLY B CA 1 ATOM 3151 C C . GLY A 1 419 ? 35.434 132.616 -36.494 1.00 20.85 ? 475 GLY B C 1 ATOM 3152 O O . GLY A 1 419 ? 36.610 132.712 -36.150 1.00 12.84 ? 475 GLY B O 1 ATOM 3153 N N . ASN A 1 420 ? 34.505 132.023 -35.740 1.00 17.90 ? 476 ASN B N 1 ATOM 3154 C CA . ASN A 1 420 ? 34.870 131.367 -34.483 1.00 26.05 ? 476 ASN B CA 1 ATOM 3155 C C . ASN A 1 420 ? 35.359 129.937 -34.668 1.00 30.17 ? 476 ASN B C 1 ATOM 3156 O O . ASN A 1 420 ? 35.811 129.297 -33.712 1.00 35.71 ? 476 ASN B O 1 ATOM 3157 C CB . ASN A 1 420 ? 33.715 131.386 -33.478 1.00 37.24 ? 476 ASN B CB 1 ATOM 3158 C CG . ASN A 1 420 ? 33.562 132.723 -32.798 1.00 53.57 ? 476 ASN B CG 1 ATOM 3159 O OD1 . ASN A 1 420 ? 34.374 133.097 -31.945 1.00 62.05 ? 476 ASN B OD1 1 ATOM 3160 N ND2 . ASN A 1 420 ? 32.514 133.453 -33.162 1.00 57.37 ? 476 ASN B ND2 1 ATOM 3161 N N . LEU A 1 421 ? 35.283 129.442 -35.900 1.00 27.59 ? 477 LEU B N 1 ATOM 3162 C CA . LEU A 1 421 ? 35.657 128.069 -36.181 1.00 20.68 ? 477 LEU B CA 1 ATOM 3163 C C . LEU A 1 421 ? 37.115 128.029 -36.581 1.00 11.01 ? 477 LEU B C 1 ATOM 3164 O O . LEU A 1 421 ? 37.475 128.476 -37.658 1.00 36.05 ? 477 LEU B O 1 ATOM 3165 C CB . LEU A 1 421 ? 34.789 127.533 -37.315 1.00 22.01 ? 477 LEU B CB 1 ATOM 3166 C CG . LEU A 1 421 ? 33.295 127.591 -37.006 1.00 16.33 ? 477 LEU B CG 1 ATOM 3167 C CD1 . LEU A 1 421 ? 32.506 126.900 -38.077 1.00 11.91 ? 477 LEU B CD1 1 ATOM 3168 C CD2 . LEU A 1 421 ? 33.023 126.940 -35.662 1.00 16.55 ? 477 LEU B CD2 1 ATOM 3169 N N . LYS A 1 422 ? 37.942 127.488 -35.692 1.00 12.48 ? 478 LYS B N 1 ATOM 3170 C CA . LYS A 1 422 ? 39.392 127.466 -35.857 1.00 13.86 ? 478 LYS B CA 1 ATOM 3171 C C . LYS A 1 422 ? 39.871 126.173 -36.489 1.00 15.70 ? 478 LYS B C 1 ATOM 3172 O O . LYS A 1 422 ? 41.037 126.056 -36.869 1.00 20.73 ? 478 LYS B O 1 ATOM 3173 C CB . LYS A 1 422 ? 40.088 127.634 -34.505 1.00 16.22 ? 478 LYS B CB 1 ATOM 3174 C CG . LYS A 1 422 ? 39.607 128.819 -33.694 1.00 18.40 ? 478 LYS B CG 1 ATOM 3175 C CD . LYS A 1 422 ? 39.827 130.119 -34.439 1.00 24.46 ? 478 LYS B CD 1 ATOM 3176 C CE . LYS A 1 422 ? 39.134 131.275 -33.742 1.00 31.35 ? 478 LYS B CE 1 ATOM 3177 N NZ . LYS A 1 422 ? 39.405 132.566 -34.435 1.00 36.76 ? 478 LYS B NZ 1 ATOM 3178 N N . ASN A 1 423 ? 38.994 125.182 -36.565 1.00 12.77 ? 479 ASN B N 1 ATOM 3179 C CA . ASN A 1 423 ? 39.344 123.938 -37.252 1.00 21.92 ? 479 ASN B CA 1 ATOM 3180 C C . ASN A 1 423 ? 38.774 123.816 -38.661 1.00 21.28 ? 479 ASN B C 1 ATOM 3181 O O . ASN A 1 423 ? 38.916 122.770 -39.293 1.00 23.59 ? 479 ASN B O 1 ATOM 3182 C CB . ASN A 1 423 ? 39.006 122.709 -36.406 1.00 23.12 ? 479 ASN B CB 1 ATOM 3183 C CG . ASN A 1 423 ? 39.518 122.830 -34.986 1.00 31.71 ? 479 ASN B CG 1 ATOM 3184 O OD1 . ASN A 1 423 ? 38.752 122.705 -34.033 1.00 37.46 ? 479 ASN B OD1 1 ATOM 3185 N ND2 . ASN A 1 423 ? 40.817 123.082 -34.834 1.00 35.75 ? 479 ASN B ND2 1 ATOM 3186 N N . LEU A 1 424 ? 38.109 124.866 -39.142 1.00 18.00 ? 480 LEU B N 1 ATOM 3187 C CA . LEU A 1 424 ? 37.373 124.747 -40.377 1.00 9.07 ? 480 LEU B CA 1 ATOM 3188 C C . LEU A 1 424 ? 38.391 124.787 -41.518 1.00 14.33 ? 480 LEU B C 1 ATOM 3189 O O . LEU A 1 424 ? 39.057 125.796 -41.751 1.00 14.51 ? 480 LEU B O 1 ATOM 3190 C CB . LEU A 1 424 ? 36.403 125.919 -40.477 1.00 21.79 ? 480 LEU B CB 1 ATOM 3191 C CG . LEU A 1 424 ? 35.429 126.015 -41.647 1.00 8.37 ? 480 LEU B CG 1 ATOM 3192 C CD1 . LEU A 1 424 ? 34.583 124.750 -41.723 1.00 8.03 ? 480 LEU B CD1 1 ATOM 3193 C CD2 . LEU A 1 424 ? 34.554 127.214 -41.433 1.00 8.47 ? 480 LEU B CD2 1 ATOM 3194 N N . ASN A 1 425 ? 38.527 123.647 -42.190 1.00 11.51 ? 481 ASN B N 1 ATOM 3195 C CA . ASN A 1 425 ? 39.471 123.462 -43.286 1.00 18.95 ? 481 ASN B CA 1 ATOM 3196 C C . ASN A 1 425 ? 38.962 123.795 -44.679 1.00 18.11 ? 481 ASN B C 1 ATOM 3197 O O . ASN A 1 425 ? 39.686 124.353 -45.508 1.00 17.89 ? 481 ASN B O 1 ATOM 3198 C CB . ASN A 1 425 ? 40.025 122.042 -43.279 1.00 20.94 ? 481 ASN B CB 1 ATOM 3199 C CG . ASN A 1 425 ? 41.112 121.854 -44.300 1.00 17.67 ? 481 ASN B CG 1 ATOM 3200 O OD1 . ASN A 1 425 ? 40.901 121.246 -45.348 1.00 18.50 ? 481 ASN B OD1 1 ATOM 3201 N ND2 . ASN A 1 425 ? 42.285 122.400 -44.011 1.00 19.21 ? 481 ASN B ND2 1 ATOM 3202 N N . PHE A 1 426 ? 37.723 123.384 -44.926 1.00 14.41 ? 482 PHE B N 1 ATOM 3203 C CA . PHE A 1 426 ? 37.156 123.326 -46.272 1.00 11.90 ? 482 PHE B CA 1 ATOM 3204 C C . PHE A 1 426 ? 35.720 123.806 -46.161 1.00 12.49 ? 482 PHE B C 1 ATOM 3205 O O . PHE A 1 426 ? 34.923 123.206 -45.424 1.00 9.41 ? 482 PHE B O 1 ATOM 3206 C CB . PHE A 1 426 ? 37.191 121.861 -46.719 1.00 7.05 ? 482 PHE B CB 1 ATOM 3207 C CG . PHE A 1 426 ? 36.665 121.600 -48.095 1.00 12.87 ? 482 PHE B CG 1 ATOM 3208 C CD1 . PHE A 1 426 ? 35.305 121.700 -48.378 1.00 16.18 ? 482 PHE B CD1 1 ATOM 3209 C CD2 . PHE A 1 426 ? 37.526 121.196 -49.104 1.00 6.77 ? 482 PHE B CD2 1 ATOM 3210 C CE1 . PHE A 1 426 ? 34.817 121.437 -49.655 1.00 10.18 ? 482 PHE B CE1 1 ATOM 3211 C CE2 . PHE A 1 426 ? 37.051 120.929 -50.380 1.00 12.94 ? 482 PHE B CE2 1 ATOM 3212 C CZ . PHE A 1 426 ? 35.698 121.042 -50.659 1.00 7.90 ? 482 PHE B CZ 1 ATOM 3213 N N . VAL A 1 427 ? 35.376 124.864 -46.889 1.00 7.04 ? 483 VAL B N 1 ATOM 3214 C CA . VAL A 1 427 ? 33.994 125.331 -46.926 1.00 17.39 ? 483 VAL B CA 1 ATOM 3215 C C . VAL A 1 427 ? 33.522 125.526 -48.357 1.00 14.52 ? 483 VAL B C 1 ATOM 3216 O O . VAL A 1 427 ? 34.151 126.254 -49.128 1.00 6.64 ? 483 VAL B O 1 ATOM 3217 C CB . VAL A 1 427 ? 33.804 126.661 -46.151 1.00 19.63 ? 483 VAL B CB 1 ATOM 3218 C CG1 . VAL A 1 427 ? 34.986 127.523 -46.344 1.00 26.11 ? 483 VAL B CG1 1 ATOM 3219 C CG2 . VAL A 1 427 ? 32.548 127.411 -46.624 1.00 6.76 ? 483 VAL B CG2 1 ATOM 3220 N N . ASP A 1 428 ? 32.419 124.871 -48.709 1.00 11.19 ? 484 ASP B N 1 ATOM 3221 C CA . ASP A 1 428 ? 31.784 125.117 -49.986 1.00 5.17 ? 484 ASP B CA 1 ATOM 3222 C C . ASP A 1 428 ? 30.342 125.572 -49.793 1.00 11.11 ? 484 ASP B C 1 ATOM 3223 O O . ASP A 1 428 ? 29.473 124.799 -49.371 1.00 15.10 ? 484 ASP B O 1 ATOM 3224 C CB . ASP A 1 428 ? 31.840 123.849 -50.835 1.00 14.00 ? 484 ASP B CB 1 ATOM 3225 C CG . ASP A 1 428 ? 31.426 124.088 -52.256 1.00 21.40 ? 484 ASP B CG 1 ATOM 3226 O OD1 . ASP A 1 428 ? 31.161 125.259 -52.595 1.00 30.18 ? 484 ASP B OD1 1 ATOM 3227 O OD2 . ASP A 1 428 ? 31.392 123.116 -53.045 1.00 24.19 ? 484 ASP B OD2 1 ATOM 3228 N N . ILE A 1 429 ? 30.118 126.857 -50.035 1.00 8.81 ? 485 ILE B N 1 ATOM 3229 C CA . ILE A 1 429 ? 28.783 127.458 -50.119 1.00 7.48 ? 485 ILE B CA 1 ATOM 3230 C C . ILE A 1 429 ? 28.307 127.856 -51.509 1.00 10.40 ? 485 ILE B C 1 ATOM 3231 O O . ILE A 1 429 ? 27.374 128.654 -51.636 1.00 5.63 ? 485 ILE B O 1 ATOM 3232 C CB . ILE A 1 429 ? 28.546 128.560 -49.098 1.00 14.86 ? 485 ILE B CB 1 ATOM 3233 C CG1 . ILE A 1 429 ? 29.331 128.247 -47.827 1.00 9.76 ? 485 ILE B CG1 1 ATOM 3234 C CG2 . ILE A 1 429 ? 27.062 128.596 -48.724 1.00 19.03 ? 485 ILE B CG2 1 ATOM 3235 C CD1 . ILE A 1 429 ? 28.816 128.956 -46.633 1.00 10.60 ? 485 ILE B CD1 1 ATOM 3236 N N . SER A 1 430 ? 29.012 127.400 -52.543 1.00 14.85 ? 486 SER B N 1 ATOM 3237 C CA . SER A 1 430 ? 28.706 127.782 -53.929 1.00 11.26 ? 486 SER B CA 1 ATOM 3238 C C . SER A 1 430 ? 27.294 127.381 -54.363 1.00 12.59 ? 486 SER B C 1 ATOM 3239 O O . SER A 1 430 ? 26.623 126.604 -53.686 1.00 3.43 ? 486 SER B O 1 ATOM 3240 C CB . SER A 1 430 ? 29.715 127.171 -54.896 1.00 11.79 ? 486 SER B CB 1 ATOM 3241 O OG . SER A 1 430 ? 29.629 125.764 -54.881 1.00 11.47 ? 486 SER B OG 1 ATOM 3242 N N . GLU A 1 431 ? 26.818 128.007 -55.437 1.00 8.18 ? 487 GLU B N 1 ATOM 3243 C CA . GLU A 1 431 ? 25.460 127.789 -55.954 1.00 9.69 ? 487 GLU B CA 1 ATOM 3244 C C . GLU A 1 431 ? 24.341 127.971 -54.930 1.00 6.46 ? 487 GLU B C 1 ATOM 3245 O O . GLU A 1 431 ? 23.639 127.026 -54.579 1.00 5.76 ? 487 GLU B O 1 ATOM 3246 C CB . GLU A 1 431 ? 25.338 126.432 -56.642 1.00 9.04 ? 487 GLU B CB 1 ATOM 3247 C CG . GLU A 1 431 ? 25.951 126.411 -58.043 1.00 5.04 ? 487 GLU B CG 1 ATOM 3248 C CD . GLU A 1 431 ? 25.784 125.070 -58.719 1.00 16.94 ? 487 GLU B CD 1 ATOM 3249 O OE1 . GLU A 1 431 ? 25.322 125.046 -59.881 1.00 24.11 ? 487 GLU B OE1 1 ATOM 3250 O OE2 . GLU A 1 431 ? 26.130 124.041 -58.089 1.00 19.53 ? 487 GLU B OE2 1 ATOM 3251 N N . ASN A 1 432 ? 24.188 129.199 -54.461 1.00 10.22 ? 488 ASN B N 1 ATOM 3252 C CA . ASN A 1 432 ? 23.156 129.533 -53.506 1.00 11.56 ? 488 ASN B CA 1 ATOM 3253 C C . ASN A 1 432 ? 22.673 130.939 -53.815 1.00 12.58 ? 488 ASN B C 1 ATOM 3254 O O . ASN A 1 432 ? 22.996 131.483 -54.853 1.00 16.68 ? 488 ASN B O 1 ATOM 3255 C CB . ASN A 1 432 ? 23.671 129.399 -52.062 1.00 12.45 ? 488 ASN B CB 1 ATOM 3256 C CG . ASN A 1 432 ? 23.500 127.973 -51.502 1.00 11.39 ? 488 ASN B CG 1 ATOM 3257 O OD1 . ASN A 1 432 ? 22.389 127.545 -51.190 1.00 11.54 ? 488 ASN B OD1 1 ATOM 3258 N ND2 . ASN A 1 432 ? 24.598 127.244 -51.381 1.00 8.24 ? 488 ASN B ND2 1 ATOM 3259 N N . ARG A 1 433 ? 21.830 131.489 -52.964 1.00 11.81 ? 489 ARG B N 1 ATOM 3260 C CA . ARG A 1 433 ? 21.344 132.856 -53.126 1.00 11.20 ? 489 ARG B CA 1 ATOM 3261 C C . ARG A 1 433 ? 21.969 133.890 -52.178 1.00 12.21 ? 489 ARG B C 1 ATOM 3262 O O . ARG A 1 433 ? 21.387 134.956 -51.941 1.00 18.02 ? 489 ARG B O 1 ATOM 3263 C CB . ARG A 1 433 ? 19.816 132.892 -53.196 1.00 18.09 ? 489 ARG B CB 1 ATOM 3264 C CG . ARG A 1 433 ? 19.267 131.733 -54.029 1.00 27.31 ? 489 ARG B CG 1 ATOM 3265 C CD . ARG A 1 433 ? 18.600 132.154 -55.326 1.00 33.66 ? 489 ARG B CD 1 ATOM 3266 N NE . ARG A 1 433 ? 17.143 132.019 -55.222 1.00 46.70 ? 489 ARG B NE 1 ATOM 3267 C CZ . ARG A 1 433 ? 16.410 131.075 -55.816 1.00 44.71 ? 489 ARG B CZ 1 ATOM 3268 N NH1 . ARG A 1 433 ? 16.971 130.161 -56.600 1.00 35.19 ? 489 ARG B NH1 1 ATOM 3269 N NH2 . ARG A 1 433 ? 15.096 131.059 -55.635 1.00 47.51 ? 489 ARG B NH2 1 ATOM 3270 N N . LEU A 1 434 ? 23.075 133.519 -51.532 1.00 15.50 ? 490 LEU B N 1 ATOM 3271 C CA . LEU A 1 434 ? 23.752 134.399 -50.554 1.00 16.54 ? 490 LEU B CA 1 ATOM 3272 C C . LEU A 1 434 ? 24.006 135.832 -51.050 1.00 16.20 ? 490 LEU B C 1 ATOM 3273 O O . LEU A 1 434 ? 24.411 136.054 -52.196 1.00 19.27 ? 490 LEU B O 1 ATOM 3274 C CB . LEU A 1 434 ? 25.105 133.806 -50.173 1.00 6.32 ? 490 LEU B CB 1 ATOM 3275 C CG . LEU A 1 434 ? 25.132 132.431 -49.519 1.00 11.42 ? 490 LEU B CG 1 ATOM 3276 C CD1 . LEU A 1 434 ? 26.561 131.988 -49.362 1.00 7.38 ? 490 LEU B CD1 1 ATOM 3277 C CD2 . LEU A 1 434 ? 24.446 132.494 -48.188 1.00 5.97 ? 490 LEU B CD2 1 ATOM 3278 N N . VAL A 1 435 ? 23.785 136.798 -50.172 1.00 17.31 ? 491 VAL B N 1 ATOM 3279 C CA . VAL A 1 435 ? 23.955 138.216 -50.507 1.00 17.10 ? 491 VAL B CA 1 ATOM 3280 C C . VAL A 1 435 ? 24.947 138.892 -49.583 1.00 8.65 ? 491 VAL B C 1 ATOM 3281 O O . VAL A 1 435 ? 25.542 138.244 -48.731 1.00 23.68 ? 491 VAL B O 1 ATOM 3282 C CB . VAL A 1 435 ? 22.606 138.975 -50.467 1.00 8.02 ? 491 VAL B CB 1 ATOM 3283 C CG1 . VAL A 1 435 ? 21.720 138.513 -51.615 1.00 7.44 ? 491 VAL B CG1 1 ATOM 3284 C CG2 . VAL A 1 435 ? 21.894 138.759 -49.123 1.00 8.04 ? 491 VAL B CG2 1 ATOM 3285 N N . GLY A 1 436 ? 25.137 140.194 -49.767 1.00 31.53 ? 492 GLY B N 1 ATOM 3286 C CA . GLY A 1 436 ? 26.025 140.990 -48.930 1.00 10.04 ? 492 GLY B CA 1 ATOM 3287 C C . GLY A 1 436 ? 27.518 140.807 -49.165 1.00 13.00 ? 492 GLY B C 1 ATOM 3288 O O . GLY A 1 436 ? 27.946 140.215 -50.143 1.00 19.20 ? 492 GLY B O 1 ATOM 3289 N N . SER A 1 437 ? 28.316 141.346 -48.255 1.00 15.65 ? 493 SER B N 1 ATOM 3290 C CA . SER A 1 437 ? 29.769 141.230 -48.305 1.00 19.76 ? 493 SER B CA 1 ATOM 3291 C C . SER A 1 437 ? 30.286 139.904 -47.774 1.00 19.03 ? 493 SER B C 1 ATOM 3292 O O . SER A 1 437 ? 29.603 139.228 -47.009 1.00 22.32 ? 493 SER B O 1 ATOM 3293 C CB . SER A 1 437 ? 30.405 142.365 -47.499 1.00 12.27 ? 493 SER B CB 1 ATOM 3294 O OG . SER A 1 437 ? 30.273 143.584 -48.195 1.00 29.58 ? 493 SER B OG 1 ATOM 3295 N N . ILE A 1 438 ? 31.490 139.528 -48.192 1.00 15.54 ? 494 ILE B N 1 ATOM 3296 C CA . ILE A 1 438 ? 32.245 138.521 -47.467 1.00 18.19 ? 494 ILE B CA 1 ATOM 3297 C C . ILE A 1 438 ? 32.705 139.145 -46.137 1.00 27.36 ? 494 ILE B C 1 ATOM 3298 O O . ILE A 1 438 ? 33.450 140.136 -46.132 1.00 28.32 ? 494 ILE B O 1 ATOM 3299 C CB . ILE A 1 438 ? 33.462 138.066 -48.267 1.00 17.95 ? 494 ILE B CB 1 ATOM 3300 C CG1 . ILE A 1 438 ? 33.022 137.275 -49.492 1.00 20.29 ? 494 ILE B CG1 1 ATOM 3301 C CG2 . ILE A 1 438 ? 34.342 137.190 -47.423 1.00 19.91 ? 494 ILE B CG2 1 ATOM 3302 C CD1 . ILE A 1 438 ? 34.070 137.208 -50.578 1.00 18.99 ? 494 ILE B CD1 1 ATOM 3303 N N . PRO A 1 439 ? 32.233 138.591 -45.002 1.00 24.43 ? 495 PRO B N 1 ATOM 3304 C CA . PRO A 1 439 ? 32.489 139.214 -43.688 1.00 16.65 ? 495 PRO B CA 1 ATOM 3305 C C . PRO A 1 439 ? 33.950 139.143 -43.254 1.00 22.64 ? 495 PRO B C 1 ATOM 3306 O O . PRO A 1 439 ? 34.528 138.057 -43.236 1.00 28.75 ? 495 PRO B O 1 ATOM 3307 C CB . PRO A 1 439 ? 31.623 138.387 -42.732 1.00 11.82 ? 495 PRO B CB 1 ATOM 3308 C CG . PRO A 1 439 ? 31.510 137.043 -43.401 1.00 21.16 ? 495 PRO B CG 1 ATOM 3309 C CD . PRO A 1 439 ? 31.469 137.332 -44.888 1.00 18.39 ? 495 PRO B CD 1 ATOM 3310 N N . PRO A 1 440 ? 34.528 140.285 -42.851 1.00 24.59 ? 496 PRO B N 1 ATOM 3311 C CA . PRO A 1 440 ? 35.916 140.387 -42.377 1.00 22.57 ? 496 PRO B CA 1 ATOM 3312 C C . PRO A 1 440 ? 36.287 139.342 -41.324 1.00 25.26 ? 496 PRO B C 1 ATOM 3313 O O . PRO A 1 440 ? 37.439 138.883 -41.295 1.00 29.86 ? 496 PRO B O 1 ATOM 3314 C CB . PRO A 1 440 ? 35.960 141.790 -41.773 1.00 15.36 ? 496 PRO B CB 1 ATOM 3315 C CG . PRO A 1 440 ? 35.006 142.566 -42.629 1.00 26.77 ? 496 PRO B CG 1 ATOM 3316 C CD . PRO A 1 440 ? 33.886 141.610 -42.955 1.00 24.47 ? 496 PRO B CD 1 ATOM 3317 N N . ALA A 1 441 ? 35.321 138.957 -40.488 1.00 20.68 ? 497 ALA B N 1 ATOM 3318 C CA . ALA A 1 441 ? 35.574 138.000 -39.408 1.00 19.12 ? 497 ALA B CA 1 ATOM 3319 C C . ALA A 1 441 ? 36.043 136.617 -39.895 1.00 20.41 ? 497 ALA B C 1 ATOM 3320 O O . ALA A 1 441 ? 36.527 135.815 -39.105 1.00 15.29 ? 497 ALA B O 1 ATOM 3321 C CB . ALA A 1 441 ? 34.357 137.860 -38.529 1.00 13.64 ? 497 ALA B CB 1 ATOM 3322 N N . ILE A 1 442 ? 35.900 136.329 -41.187 1.00 21.10 ? 498 ILE B N 1 ATOM 3323 C CA . ILE A 1 442 ? 36.354 135.041 -41.701 1.00 25.14 ? 498 ILE B CA 1 ATOM 3324 C C . ILE A 1 442 ? 37.882 134.959 -41.624 1.00 28.87 ? 498 ILE B C 1 ATOM 3325 O O . ILE A 1 442 ? 38.468 133.881 -41.709 1.00 31.07 ? 498 ILE B O 1 ATOM 3326 C CB . ILE A 1 442 ? 35.801 134.748 -43.140 1.00 39.20 ? 498 ILE B CB 1 ATOM 3327 C CG1 . ILE A 1 442 ? 36.097 133.309 -43.567 1.00 35.98 ? 498 ILE B CG1 1 ATOM 3328 C CG2 . ILE A 1 442 ? 36.343 135.727 -44.160 1.00 32.75 ? 498 ILE B CG2 1 ATOM 3329 C CD1 . ILE A 1 442 ? 35.501 132.947 -44.900 1.00 30.55 ? 498 ILE B CD1 1 ATOM 3330 N N . SER A 1 443 ? 38.518 136.111 -41.421 1.00 30.57 ? 499 SER B N 1 ATOM 3331 C CA . SER A 1 443 ? 39.952 136.162 -41.174 1.00 31.72 ? 499 SER B CA 1 ATOM 3332 C C . SER A 1 443 ? 40.302 135.312 -39.955 1.00 30.70 ? 499 SER B C 1 ATOM 3333 O O . SER A 1 443 ? 41.440 134.881 -39.774 1.00 35.83 ? 499 SER B O 1 ATOM 3334 C CB . SER A 1 443 ? 40.357 137.601 -40.904 1.00 31.86 ? 499 SER B CB 1 ATOM 3335 O OG . SER A 1 443 ? 39.593 138.107 -39.823 1.00 31.51 ? 499 SER B OG 1 ATOM 3336 N N . GLY A 1 444 ? 39.304 135.072 -39.120 1.00 28.06 ? 500 GLY B N 1 ATOM 3337 C CA . GLY A 1 444 ? 39.490 134.311 -37.904 1.00 28.92 ? 500 GLY B CA 1 ATOM 3338 C C . GLY A 1 444 ? 39.553 132.806 -38.094 1.00 34.11 ? 500 GLY B C 1 ATOM 3339 O O . GLY A 1 444 ? 39.829 132.096 -37.128 1.00 31.13 ? 500 GLY B O 1 ATOM 3340 N N . CYS A 1 445 ? 39.328 132.303 -39.311 1.00 29.37 ? 501 CYS B N 1 ATOM 3341 C CA . CYS A 1 445 ? 39.401 130.862 -39.486 1.00 29.16 ? 501 CYS B CA 1 ATOM 3342 C C . CYS A 1 445 ? 40.832 130.547 -39.863 1.00 32.10 ? 501 CYS B C 1 ATOM 3343 O O . CYS A 1 445 ? 41.204 130.586 -41.040 1.00 26.32 ? 501 CYS B O 1 ATOM 3344 C CB . CYS A 1 445 ? 38.505 130.418 -40.646 1.00 28.06 ? 501 CYS B CB 1 ATOM 3345 S SG . CYS A 1 445 ? 36.739 130.742 -40.478 1.00 15.74 ? 501 CYS B SG 1 ATOM 3346 N N . GLU A 1 446 ? 41.601 130.092 -38.883 1.00 37.07 ? 502 GLU B N 1 ATOM 3347 C CA . GLU A 1 446 ? 43.044 130.032 -39.063 1.00 38.60 ? 502 GLU B CA 1 ATOM 3348 C C . GLU A 1 446 ? 43.477 128.774 -39.808 1.00 28.68 ? 502 GLU B C 1 ATOM 3349 O O . GLU A 1 446 ? 44.613 128.672 -40.257 1.00 26.64 ? 502 GLU B O 1 ATOM 3350 C CB . GLU A 1 446 ? 43.783 130.202 -37.726 1.00 44.65 ? 502 GLU B CB 1 ATOM 3351 C CG . GLU A 1 446 ? 43.259 129.354 -36.572 1.00 58.01 ? 502 GLU B CG 1 ATOM 3352 C CD . GLU A 1 446 ? 43.627 129.935 -35.196 1.00 69.54 ? 502 GLU B CD 1 ATOM 3353 O OE1 . GLU A 1 446 ? 43.805 129.148 -34.231 1.00 67.67 ? 502 GLU B OE1 1 ATOM 3354 O OE2 . GLU A 1 446 ? 43.725 131.181 -35.080 1.00 74.84 ? 502 GLU B OE2 1 ATOM 3355 N N . SER A 1 447 ? 42.561 127.818 -39.917 1.00 21.78 ? 503 SER B N 1 ATOM 3356 C CA . SER A 1 447 ? 42.824 126.567 -40.611 1.00 13.98 ? 503 SER B CA 1 ATOM 3357 C C . SER A 1 447 ? 42.262 126.515 -42.032 1.00 17.09 ? 503 SER B C 1 ATOM 3358 O O . SER A 1 447 ? 42.364 125.486 -42.705 1.00 16.75 ? 503 SER B O 1 ATOM 3359 C CB . SER A 1 447 ? 42.286 125.397 -39.789 1.00 17.59 ? 503 SER B CB 1 ATOM 3360 O OG . SER A 1 447 ? 43.165 125.094 -38.720 1.00 21.99 ? 503 SER B OG 1 ATOM 3361 N N . LEU A 1 448 ? 41.640 127.604 -42.476 1.00 15.34 ? 504 LEU B N 1 ATOM 3362 C CA . LEU A 1 448 ? 40.887 127.562 -43.717 1.00 11.85 ? 504 LEU B CA 1 ATOM 3363 C C . LEU A 1 448 ? 41.793 127.418 -44.943 1.00 15.78 ? 504 LEU B C 1 ATOM 3364 O O . LEU A 1 448 ? 42.724 128.199 -45.138 1.00 12.18 ? 504 LEU B O 1 ATOM 3365 C CB . LEU A 1 448 ? 39.991 128.783 -43.845 1.00 17.63 ? 504 LEU B CB 1 ATOM 3366 C CG . LEU A 1 448 ? 39.040 128.743 -45.031 1.00 10.41 ? 504 LEU B CG 1 ATOM 3367 C CD1 . LEU A 1 448 ? 38.094 127.544 -44.865 1.00 9.55 ? 504 LEU B CD1 1 ATOM 3368 C CD2 . LEU A 1 448 ? 38.289 130.049 -45.097 1.00 10.51 ? 504 LEU B CD2 1 ATOM 3369 N N . GLU A 1 449 ? 41.500 126.400 -45.749 1.00 13.58 ? 505 GLU B N 1 ATOM 3370 C CA . GLU A 1 449 ? 42.324 125.999 -46.895 1.00 15.64 ? 505 GLU B CA 1 ATOM 3371 C C . GLU A 1 449 ? 41.590 126.136 -48.220 1.00 11.61 ? 505 GLU B C 1 ATOM 3372 O O . GLU A 1 449 ? 42.149 126.642 -49.193 1.00 10.75 ? 505 GLU B O 1 ATOM 3373 C CB . GLU A 1 449 ? 42.973 124.620 -46.703 1.00 22.79 ? 505 GLU B CB 1 ATOM 3374 C CG . GLU A 1 449 ? 44.204 124.669 -45.766 1.00 26.74 ? 505 GLU B CG 1 ATOM 3375 C CD . GLU A 1 449 ? 44.932 123.329 -45.619 1.00 36.87 ? 505 GLU B CD 1 ATOM 3376 O OE1 . GLU A 1 449 ? 44.263 122.286 -45.432 1.00 39.30 ? 505 GLU B OE1 1 ATOM 3377 O OE2 . GLU A 1 449 ? 46.183 123.323 -45.683 1.00 38.85 ? 505 GLU B OE2 1 ATOM 3378 N N . PHE A 1 450 ? 40.392 125.559 -48.275 1.00 16.34 ? 506 PHE B N 1 ATOM 3379 C CA . PHE A 1 450 ? 39.512 125.595 -49.441 1.00 8.96 ? 506 PHE B CA 1 ATOM 3380 C C . PHE A 1 450 ? 38.288 126.499 -49.178 1.00 14.97 ? 506 PHE B C 1 ATOM 3381 O O . PHE A 1 450 ? 37.545 126.273 -48.221 1.00 15.96 ? 506 PHE B O 1 ATOM 3382 C CB . PHE A 1 450 ? 39.082 124.159 -49.732 1.00 23.81 ? 506 PHE B CB 1 ATOM 3383 C CG . PHE A 1 450 ? 38.189 123.999 -50.930 1.00 29.97 ? 506 PHE B CG 1 ATOM 3384 C CD1 . PHE A 1 450 ? 36.820 124.207 -50.833 1.00 28.62 ? 506 PHE B CD1 1 ATOM 3385 C CD2 . PHE A 1 450 ? 38.720 123.593 -52.160 1.00 31.87 ? 506 PHE B CD2 1 ATOM 3386 C CE1 . PHE A 1 450 ? 35.992 124.036 -51.960 1.00 30.84 ? 506 PHE B CE1 1 ATOM 3387 C CE2 . PHE A 1 450 ? 37.911 123.421 -53.273 1.00 24.23 ? 506 PHE B CE2 1 ATOM 3388 C CZ . PHE A 1 450 ? 36.542 123.641 -53.175 1.00 27.06 ? 506 PHE B CZ 1 ATOM 3389 N N . LEU A 1 451 ? 38.094 127.536 -49.998 1.00 14.64 ? 507 LEU B N 1 ATOM 3390 C CA . LEU A 1 451 ? 36.908 128.395 -49.888 1.00 8.50 ? 507 LEU B CA 1 ATOM 3391 C C . LEU A 1 451 ? 36.184 128.571 -51.229 1.00 20.54 ? 507 LEU B C 1 ATOM 3392 O O . LEU A 1 451 ? 36.676 129.290 -52.127 1.00 14.47 ? 507 LEU B O 1 ATOM 3393 C CB . LEU A 1 451 ? 37.310 129.771 -49.356 1.00 9.24 ? 507 LEU B CB 1 ATOM 3394 C CG . LEU A 1 451 ? 36.213 130.831 -49.200 1.00 19.45 ? 507 LEU B CG 1 ATOM 3395 C CD1 . LEU A 1 451 ? 35.093 130.339 -48.317 1.00 12.11 ? 507 LEU B CD1 1 ATOM 3396 C CD2 . LEU A 1 451 ? 36.778 132.144 -48.635 1.00 21.05 ? 507 LEU B CD2 1 ATOM 3397 N N . ASP A 1 452 ? 35.005 127.958 -51.357 1.00 7.29 ? 508 ASP B N 1 ATOM 3398 C CA . ASP A 1 452 ? 34.252 128.061 -52.594 1.00 6.85 ? 508 ASP B CA 1 ATOM 3399 C C . ASP A 1 452 ? 32.906 128.765 -52.379 1.00 11.73 ? 508 ASP B C 1 ATOM 3400 O O . ASP A 1 452 ? 31.929 128.152 -51.932 1.00 8.78 ? 508 ASP B O 1 ATOM 3401 C CB . ASP A 1 452 ? 34.021 126.650 -53.158 1.00 22.08 ? 508 ASP B CB 1 ATOM 3402 C CG . ASP A 1 452 ? 33.677 126.639 -54.660 1.00 22.59 ? 508 ASP B CG 1 ATOM 3403 O OD1 . ASP A 1 452 ? 33.091 127.613 -55.192 1.00 22.68 ? 508 ASP B OD1 1 ATOM 3404 O OD2 . ASP A 1 452 ? 33.992 125.622 -55.309 1.00 28.79 ? 508 ASP B OD2 1 ATOM 3405 N N . LEU A 1 453 ? 32.867 130.041 -52.754 1.00 8.22 ? 509 LEU B N 1 ATOM 3406 C CA . LEU A 1 453 ? 31.664 130.871 -52.760 1.00 6.79 ? 509 LEU B CA 1 ATOM 3407 C C . LEU A 1 453 ? 31.011 131.093 -54.155 1.00 14.99 ? 509 LEU B C 1 ATOM 3408 O O . LEU A 1 453 ? 30.182 131.983 -54.304 1.00 9.04 ? 509 LEU B O 1 ATOM 3409 C CB . LEU A 1 453 ? 31.930 132.199 -52.054 1.00 12.34 ? 509 LEU B CB 1 ATOM 3410 C CG . LEU A 1 453 ? 32.434 132.075 -50.609 1.00 17.93 ? 509 LEU B CG 1 ATOM 3411 C CD1 . LEU A 1 453 ? 32.801 133.416 -50.016 1.00 14.35 ? 509 LEU B CD1 1 ATOM 3412 C CD2 . LEU A 1 453 ? 31.393 131.400 -49.750 1.00 27.35 ? 509 LEU B CD2 1 ATOM 3413 N N . HIS A 1 454 ? 31.432 130.383 -55.194 1.00 6.22 ? 510 HIS B N 1 ATOM 3414 C CA . HIS A 1 454 ? 30.977 130.771 -56.539 1.00 8.36 ? 510 HIS B CA 1 ATOM 3415 C C . HIS A 1 454 ? 29.454 130.674 -56.812 1.00 12.87 ? 510 HIS B C 1 ATOM 3416 O O . HIS A 1 454 ? 28.749 129.903 -56.172 1.00 14.76 ? 510 HIS B O 1 ATOM 3417 C CB . HIS A 1 454 ? 31.798 130.080 -57.653 1.00 6.02 ? 510 HIS B CB 1 ATOM 3418 C CG . HIS A 1 454 ? 31.380 128.671 -57.943 1.00 11.11 ? 510 HIS B CG 1 ATOM 3419 N ND1 . HIS A 1 454 ? 32.095 127.574 -57.505 1.00 14.79 ? 510 HIS B ND1 1 ATOM 3420 C CD2 . HIS A 1 454 ? 30.340 128.176 -58.659 1.00 6.45 ? 510 HIS B CD2 1 ATOM 3421 C CE1 . HIS A 1 454 ? 31.504 126.467 -57.921 1.00 9.41 ? 510 HIS B CE1 1 ATOM 3422 N NE2 . HIS A 1 454 ? 30.436 126.805 -58.623 1.00 9.42 ? 510 HIS B NE2 1 ATOM 3423 N N . THR A 1 455 ? 28.966 131.465 -57.771 1.00 12.45 ? 511 THR B N 1 ATOM 3424 C CA . THR A 1 455 ? 27.553 131.456 -58.173 1.00 6.64 ? 511 THR B CA 1 ATOM 3425 C C . THR A 1 455 ? 26.633 131.795 -56.989 1.00 17.68 ? 511 THR B C 1 ATOM 3426 O O . THR A 1 455 ? 25.851 130.974 -56.484 1.00 13.50 ? 511 THR B O 1 ATOM 3427 C CB . THR A 1 455 ? 27.154 130.152 -58.938 1.00 14.82 ? 511 THR B CB 1 ATOM 3428 O OG1 . THR A 1 455 ? 27.888 130.086 -60.169 1.00 7.15 ? 511 THR B OG1 1 ATOM 3429 C CG2 . THR A 1 455 ? 25.639 130.105 -59.281 1.00 3.81 ? 511 THR B CG2 1 ATOM 3430 N N . ASN A 1 456 ? 26.780 133.033 -56.534 1.00 18.05 ? 512 ASN B N 1 ATOM 3431 C CA . ASN A 1 456 ? 25.937 133.587 -55.503 1.00 8.36 ? 512 ASN B CA 1 ATOM 3432 C C . ASN A 1 456 ? 25.665 135.027 -55.886 1.00 14.55 ? 512 ASN B C 1 ATOM 3433 O O . ASN A 1 456 ? 26.066 135.465 -56.958 1.00 17.82 ? 512 ASN B O 1 ATOM 3434 C CB . ASN A 1 456 ? 26.636 133.511 -54.144 1.00 7.07 ? 512 ASN B CB 1 ATOM 3435 C CG . ASN A 1 456 ? 26.358 132.206 -53.422 1.00 10.01 ? 512 ASN B CG 1 ATOM 3436 O OD1 . ASN A 1 456 ? 25.225 131.943 -53.026 1.00 6.37 ? 512 ASN B OD1 1 ATOM 3437 N ND2 . ASN A 1 456 ? 27.392 131.390 -53.234 1.00 6.21 ? 512 ASN B ND2 1 ATOM 3438 N N . SER A 1 457 ? 24.954 135.745 -55.032 1.00 13.98 ? 513 SER B N 1 ATOM 3439 C CA . SER A 1 457 ? 24.698 137.172 -55.214 1.00 13.11 ? 513 SER B CA 1 ATOM 3440 C C . SER A 1 457 ? 25.599 138.087 -54.393 1.00 16.73 ? 513 SER B C 1 ATOM 3441 O O . SER A 1 457 ? 25.200 139.211 -54.056 1.00 14.17 ? 513 SER B O 1 ATOM 3442 C CB . SER A 1 457 ? 23.222 137.513 -55.093 1.00 20.74 ? 513 SER B CB 1 ATOM 3443 O OG . SER A 1 457 ? 22.527 136.863 -56.143 1.00 25.95 ? 513 SER B OG 1 ATOM 3444 N N . LEU A 1 458 ? 26.724 137.550 -53.924 1.00 12.23 ? 514 LEU B N 1 ATOM 3445 C CA . LEU A 1 458 ? 27.650 138.317 -53.101 1.00 8.49 ? 514 LEU B CA 1 ATOM 3446 C C . LEU A 1 458 ? 28.056 139.604 -53.796 1.00 13.06 ? 514 LEU B C 1 ATOM 3447 O O . LEU A 1 458 ? 28.116 139.659 -55.023 1.00 21.09 ? 514 LEU B O 1 ATOM 3448 C CB . LEU A 1 458 ? 28.904 137.492 -52.804 1.00 9.23 ? 514 LEU B CB 1 ATOM 3449 C CG . LEU A 1 458 ? 28.726 136.201 -52.002 1.00 8.54 ? 514 LEU B CG 1 ATOM 3450 C CD1 . LEU A 1 458 ? 30.063 135.499 -51.755 1.00 8.67 ? 514 LEU B CD1 1 ATOM 3451 C CD2 . LEU A 1 458 ? 28.041 136.540 -50.714 1.00 8.20 ? 514 LEU B CD2 1 ATOM 3452 N N . SER A 1 459 ? 28.330 140.641 -53.014 1.00 9.76 ? 515 SER B N 1 ATOM 3453 C CA . SER A 1 459 ? 28.750 141.923 -53.559 1.00 10.41 ? 515 SER B CA 1 ATOM 3454 C C . SER A 1 459 ? 29.604 142.707 -52.590 1.00 14.55 ? 515 SER B C 1 ATOM 3455 O O . SER A 1 459 ? 30.009 142.215 -51.537 1.00 25.27 ? 515 SER B O 1 ATOM 3456 C CB . SER A 1 459 ? 27.549 142.788 -53.902 1.00 15.94 ? 515 SER B CB 1 ATOM 3457 O OG . SER A 1 459 ? 27.015 143.328 -52.709 1.00 23.11 ? 515 SER B OG 1 ATOM 3458 N N . GLY A 1 460 ? 29.859 143.957 -52.949 1.00 17.70 ? 516 GLY B N 1 ATOM 3459 C CA . GLY A 1 460 ? 30.724 144.787 -52.146 1.00 13.82 ? 516 GLY B CA 1 ATOM 3460 C C . GLY A 1 460 ? 32.158 144.659 -52.610 1.00 17.95 ? 516 GLY B C 1 ATOM 3461 O O . GLY A 1 460 ? 32.431 144.242 -53.735 1.00 19.19 ? 516 GLY B O 1 ATOM 3462 N N . SER A 1 461 ? 33.073 145.026 -51.729 1.00 13.70 ? 517 SER B N 1 ATOM 3463 C CA . SER A 1 461 ? 34.474 145.071 -52.061 1.00 20.71 ? 517 SER B CA 1 ATOM 3464 C C . SER A 1 461 ? 35.188 143.844 -51.507 1.00 29.00 ? 517 SER B C 1 ATOM 3465 O O . SER A 1 461 ? 34.565 142.939 -50.955 1.00 32.55 ? 517 SER B O 1 ATOM 3466 C CB . SER A 1 461 ? 35.083 146.383 -51.559 1.00 16.41 ? 517 SER B CB 1 ATOM 3467 O OG . SER A 1 461 ? 36.493 146.307 -51.478 1.00 27.39 ? 517 SER B OG 1 ATOM 3468 N N . LEU A 1 462 ? 36.496 143.799 -51.706 1.00 31.43 ? 518 LEU B N 1 ATOM 3469 C CA . LEU A 1 462 ? 37.280 142.615 -51.404 1.00 35.65 ? 518 LEU B CA 1 ATOM 3470 C C . LEU A 1 462 ? 38.560 143.068 -50.716 1.00 45.38 ? 518 LEU B C 1 ATOM 3471 O O . LEU A 1 462 ? 39.359 143.789 -51.312 1.00 56.01 ? 518 LEU B O 1 ATOM 3472 C CB . LEU A 1 462 ? 37.609 141.901 -52.718 1.00 31.63 ? 518 LEU B CB 1 ATOM 3473 C CG . LEU A 1 462 ? 37.876 140.395 -52.768 1.00 34.35 ? 518 LEU B CG 1 ATOM 3474 C CD1 . LEU A 1 462 ? 36.593 139.619 -52.559 1.00 37.99 ? 518 LEU B CD1 1 ATOM 3475 C CD2 . LEU A 1 462 ? 38.519 140.000 -54.093 1.00 26.02 ? 518 LEU B CD2 1 ATOM 3476 N N . LEU A 1 463 ? 38.766 142.671 -49.468 1.00 47.32 ? 519 LEU B N 1 ATOM 3477 C CA . LEU A 1 463 ? 39.942 143.144 -48.743 1.00 54.83 ? 519 LEU B CA 1 ATOM 3478 C C . LEU A 1 463 ? 40.885 141.974 -48.449 1.00 56.68 ? 519 LEU B C 1 ATOM 3479 O O . LEU A 1 463 ? 40.435 140.870 -48.134 1.00 60.13 ? 519 LEU B O 1 ATOM 3480 C CB . LEU A 1 463 ? 39.551 143.856 -47.437 1.00 52.26 ? 519 LEU B CB 1 ATOM 3481 C CG . LEU A 1 463 ? 38.642 145.093 -47.329 1.00 41.81 ? 519 LEU B CG 1 ATOM 3482 C CD1 . LEU A 1 463 ? 38.005 145.524 -48.640 1.00 38.09 ? 519 LEU B CD1 1 ATOM 3483 C CD2 . LEU A 1 463 ? 37.558 144.860 -46.260 1.00 30.09 ? 519 LEU B CD2 1 ATOM 3484 N N . GLY A 1 464 ? 42.188 142.211 -48.555 1.00 49.19 ? 520 GLY B N 1 ATOM 3485 C CA . GLY A 1 464 ? 43.161 141.200 -48.190 1.00 50.95 ? 520 GLY B CA 1 ATOM 3486 C C . GLY A 1 464 ? 43.071 140.886 -46.707 1.00 60.36 ? 520 GLY B C 1 ATOM 3487 O O . GLY A 1 464 ? 43.334 139.760 -46.284 1.00 60.88 ? 520 GLY B O 1 ATOM 3488 N N . THR A 1 465 ? 42.686 141.894 -45.922 1.00 61.90 ? 521 THR B N 1 ATOM 3489 C CA . THR A 1 465 ? 42.504 141.767 -44.473 1.00 62.20 ? 521 THR B CA 1 ATOM 3490 C C . THR A 1 465 ? 41.348 140.834 -44.120 1.00 48.93 ? 521 THR B C 1 ATOM 3491 O O . THR A 1 465 ? 41.209 140.371 -42.984 1.00 41.14 ? 521 THR B O 1 ATOM 3492 C CB . THR A 1 465 ? 42.187 143.137 -43.847 1.00 72.17 ? 521 THR B CB 1 ATOM 3493 O OG1 . THR A 1 465 ? 41.087 143.736 -44.549 1.00 75.57 ? 521 THR B OG1 1 ATOM 3494 C CG2 . THR A 1 465 ? 43.401 144.061 -43.921 1.00 74.33 ? 521 THR B CG2 1 ATOM 3495 N N . THR A 1 466 ? 40.507 140.582 -45.109 1.00 38.80 ? 522 THR B N 1 ATOM 3496 C CA . THR A 1 466 ? 39.309 139.812 -44.905 1.00 39.73 ? 522 THR B CA 1 ATOM 3497 C C . THR A 1 466 ? 39.599 138.308 -45.011 1.00 47.09 ? 522 THR B C 1 ATOM 3498 O O . THR A 1 466 ? 38.796 137.492 -44.573 1.00 54.39 ? 522 THR B O 1 ATOM 3499 C CB . THR A 1 466 ? 38.225 140.284 -45.900 1.00 46.33 ? 522 THR B CB 1 ATOM 3500 O OG1 . THR A 1 466 ? 38.035 141.699 -45.749 1.00 45.61 ? 522 THR B OG1 1 ATOM 3501 C CG2 . THR A 1 466 ? 36.902 139.574 -45.677 1.00 48.07 ? 522 THR B CG2 1 ATOM 3502 N N . LEU A 1 467 ? 40.768 137.932 -45.533 1.00 42.79 ? 523 LEU B N 1 ATOM 3503 C CA . LEU A 1 467 ? 41.034 136.512 -45.807 1.00 32.67 ? 523 LEU B CA 1 ATOM 3504 C C . LEU A 1 467 ? 42.216 135.935 -45.026 1.00 30.31 ? 523 LEU B C 1 ATOM 3505 O O . LEU A 1 467 ? 43.238 136.601 -44.858 1.00 26.44 ? 523 LEU B O 1 ATOM 3506 C CB . LEU A 1 467 ? 41.279 136.309 -47.303 1.00 28.82 ? 523 LEU B CB 1 ATOM 3507 C CG . LEU A 1 467 ? 40.186 136.778 -48.276 1.00 25.72 ? 523 LEU B CG 1 ATOM 3508 C CD1 . LEU A 1 467 ? 40.664 136.670 -49.720 1.00 24.77 ? 523 LEU B CD1 1 ATOM 3509 C CD2 . LEU A 1 467 ? 38.892 135.997 -48.076 1.00 22.16 ? 523 LEU B CD2 1 ATOM 3510 N N . PRO A 1 468 ? 42.081 134.680 -44.552 1.00 27.10 ? 524 PRO B N 1 ATOM 3511 C CA . PRO A 1 468 ? 43.173 134.027 -43.812 1.00 19.41 ? 524 PRO B CA 1 ATOM 3512 C C . PRO A 1 468 ? 44.295 133.555 -44.728 1.00 22.86 ? 524 PRO B C 1 ATOM 3513 O O . PRO A 1 468 ? 44.010 133.025 -45.805 1.00 28.33 ? 524 PRO B O 1 ATOM 3514 C CB . PRO A 1 468 ? 42.481 132.848 -43.105 1.00 17.44 ? 524 PRO B CB 1 ATOM 3515 C CG . PRO A 1 468 ? 41.218 132.607 -43.856 1.00 16.07 ? 524 PRO B CG 1 ATOM 3516 C CD . PRO A 1 468 ? 40.824 133.911 -44.509 1.00 22.42 ? 524 PRO B CD 1 ATOM 3517 N N . LYS A 1 469 ? 45.543 133.713 -44.286 1.00 24.24 ? 525 LYS B N 1 ATOM 3518 C CA . LYS A 1 469 ? 46.724 133.525 -45.135 1.00 26.53 ? 525 LYS B CA 1 ATOM 3519 C C . LYS A 1 469 ? 47.077 132.065 -45.420 1.00 29.20 ? 525 LYS B C 1 ATOM 3520 O O . LYS A 1 469 ? 47.948 131.770 -46.243 1.00 41.84 ? 525 LYS B O 1 ATOM 3521 C CB . LYS A 1 469 ? 47.931 134.245 -44.531 1.00 34.82 ? 525 LYS B CB 1 ATOM 3522 C CG . LYS A 1 469 ? 48.005 135.725 -44.871 1.00 43.50 ? 525 LYS B CG 1 ATOM 3523 C CD . LYS A 1 469 ? 46.879 136.530 -44.234 1.00 48.00 ? 525 LYS B CD 1 ATOM 3524 C CE . LYS A 1 469 ? 46.696 137.867 -44.944 1.00 56.73 ? 525 LYS B CE 1 ATOM 3525 N NZ . LYS A 1 469 ? 45.533 138.650 -44.436 1.00 57.47 ? 525 LYS B NZ 1 ATOM 3526 N N . SER A 1 470 ? 46.384 131.159 -44.745 1.00 19.29 ? 526 SER B N 1 ATOM 3527 C CA . SER A 1 470 ? 46.509 129.730 -44.992 1.00 18.20 ? 526 SER B CA 1 ATOM 3528 C C . SER A 1 470 ? 45.686 129.277 -46.202 1.00 20.40 ? 526 SER B C 1 ATOM 3529 O O . SER A 1 470 ? 45.684 128.090 -46.531 1.00 23.07 ? 526 SER B O 1 ATOM 3530 C CB . SER A 1 470 ? 46.006 128.959 -43.770 1.00 19.03 ? 526 SER B CB 1 ATOM 3531 O OG . SER A 1 470 ? 44.604 129.168 -43.607 1.00 18.53 ? 526 SER B OG 1 ATOM 3532 N N . LEU A 1 471 ? 44.967 130.197 -46.849 1.00 16.83 ? 527 LEU B N 1 ATOM 3533 C CA . LEU A 1 471 ? 44.165 129.827 -48.031 1.00 17.45 ? 527 LEU B CA 1 ATOM 3534 C C . LEU A 1 471 ? 44.965 129.267 -49.205 1.00 13.23 ? 527 LEU B C 1 ATOM 3535 O O . LEU A 1 471 ? 46.004 129.788 -49.579 1.00 14.61 ? 527 LEU B O 1 ATOM 3536 C CB . LEU A 1 471 ? 43.285 130.984 -48.493 1.00 21.40 ? 527 LEU B CB 1 ATOM 3537 C CG . LEU A 1 471 ? 41.903 130.921 -47.843 1.00 22.98 ? 527 LEU B CG 1 ATOM 3538 C CD1 . LEU A 1 471 ? 41.076 132.189 -48.100 1.00 12.21 ? 527 LEU B CD1 1 ATOM 3539 C CD2 . LEU A 1 471 ? 41.199 129.676 -48.367 1.00 21.99 ? 527 LEU B CD2 1 ATOM 3540 N N . LYS A 1 472 ? 44.451 128.184 -49.765 1.00 25.73 ? 528 LYS B N 1 ATOM 3541 C CA . LYS A 1 472 ? 45.043 127.490 -50.907 1.00 22.80 ? 528 LYS B CA 1 ATOM 3542 C C . LYS A 1 472 ? 44.164 127.673 -52.143 1.00 25.77 ? 528 LYS B C 1 ATOM 3543 O O . LYS A 1 472 ? 44.650 128.014 -53.225 1.00 26.16 ? 528 LYS B O 1 ATOM 3544 C CB . LYS A 1 472 ? 45.276 126.004 -50.615 1.00 16.53 ? 528 LYS B CB 1 ATOM 3545 C CG . LYS A 1 472 ? 46.325 125.719 -49.546 1.00 15.16 ? 528 LYS B CG 1 ATOM 3546 C CD . LYS A 1 472 ? 46.843 124.282 -49.695 1.00 26.02 ? 528 LYS B CD 1 ATOM 3547 C CE . LYS A 1 472 ? 47.725 123.845 -48.518 1.00 36.96 ? 528 LYS B CE 1 ATOM 3548 N NZ . LYS A 1 472 ? 48.477 124.982 -47.902 1.00 46.55 ? 528 LYS B NZ 1 ATOM 3549 N N . PHE A 1 473 ? 42.889 127.322 -52.002 1.00 20.27 ? 529 PHE B N 1 ATOM 3550 C CA . PHE A 1 473 ? 41.937 127.418 -53.100 1.00 20.76 ? 529 PHE B CA 1 ATOM 3551 C C . PHE A 1 473 ? 40.894 128.511 -52.816 1.00 21.07 ? 529 PHE B C 1 ATOM 3552 O O . PHE A 1 473 ? 40.249 128.484 -51.768 1.00 27.38 ? 529 PHE B O 1 ATOM 3553 C CB . PHE A 1 473 ? 41.282 126.047 -53.288 1.00 16.04 ? 529 PHE B CB 1 ATOM 3554 C CG . PHE A 1 473 ? 40.234 125.992 -54.370 1.00 22.99 ? 529 PHE B CG 1 ATOM 3555 C CD1 . PHE A 1 473 ? 38.928 126.440 -54.133 1.00 23.36 ? 529 PHE B CD1 1 ATOM 3556 C CD2 . PHE A 1 473 ? 40.538 125.454 -55.619 1.00 19.53 ? 529 PHE B CD2 1 ATOM 3557 C CE1 . PHE A 1 473 ? 37.959 126.371 -55.134 1.00 18.34 ? 529 PHE B CE1 1 ATOM 3558 C CE2 . PHE A 1 473 ? 39.577 125.392 -56.618 1.00 12.52 ? 529 PHE B CE2 1 ATOM 3559 C CZ . PHE A 1 473 ? 38.286 125.840 -56.374 1.00 9.99 ? 529 PHE B CZ 1 ATOM 3560 N N . ILE A 1 474 ? 40.733 129.467 -53.738 1.00 16.54 ? 530 ILE B N 1 ATOM 3561 C CA . ILE A 1 474 ? 39.677 130.490 -53.623 1.00 16.85 ? 530 ILE B CA 1 ATOM 3562 C C . ILE A 1 474 ? 38.818 130.546 -54.882 1.00 16.30 ? 530 ILE B C 1 ATOM 3563 O O . ILE A 1 474 ? 39.343 130.703 -55.977 1.00 19.97 ? 530 ILE B O 1 ATOM 3564 C CB . ILE A 1 474 ? 40.245 131.919 -53.420 1.00 18.05 ? 530 ILE B CB 1 ATOM 3565 C CG1 . ILE A 1 474 ? 40.839 132.105 -52.027 1.00 17.39 ? 530 ILE B CG1 1 ATOM 3566 C CG2 . ILE A 1 474 ? 39.157 132.969 -53.619 1.00 11.86 ? 530 ILE B CG2 1 ATOM 3567 C CD1 . ILE A 1 474 ? 41.573 133.422 -51.874 1.00 12.39 ? 530 ILE B CD1 1 ATOM 3568 N N . ASP A 1 475 ? 37.502 130.401 -54.743 1.00 17.55 ? 531 ASP B N 1 ATOM 3569 C CA . ASP A 1 475 ? 36.635 130.639 -55.886 1.00 15.70 ? 531 ASP B CA 1 ATOM 3570 C C . ASP A 1 475 ? 35.476 131.543 -55.512 1.00 13.07 ? 531 ASP B C 1 ATOM 3571 O O . ASP A 1 475 ? 34.498 131.078 -54.946 1.00 15.08 ? 531 ASP B O 1 ATOM 3572 C CB . ASP A 1 475 ? 36.079 129.292 -56.342 1.00 17.66 ? 531 ASP B CB 1 ATOM 3573 C CG . ASP A 1 475 ? 35.454 129.340 -57.715 1.00 19.51 ? 531 ASP B CG 1 ATOM 3574 O OD1 . ASP A 1 475 ? 35.215 130.448 -58.243 1.00 16.37 ? 531 ASP B OD1 1 ATOM 3575 O OD2 . ASP A 1 475 ? 35.196 128.241 -58.257 1.00 26.97 ? 531 ASP B OD2 1 ATOM 3576 N N . PHE A 1 476 ? 35.561 132.813 -55.901 1.00 18.63 ? 532 PHE B N 1 ATOM 3577 C CA . PHE A 1 476 ? 34.473 133.796 -55.734 1.00 8.66 ? 532 PHE B CA 1 ATOM 3578 C C . PHE A 1 476 ? 33.707 134.082 -57.017 1.00 10.89 ? 532 PHE B C 1 ATOM 3579 O O . PHE A 1 476 ? 32.965 135.050 -57.094 1.00 11.65 ? 532 PHE B O 1 ATOM 3580 C CB . PHE A 1 476 ? 34.954 135.091 -55.101 1.00 9.45 ? 532 PHE B CB 1 ATOM 3581 C CG . PHE A 1 476 ? 35.528 134.914 -53.728 1.00 14.38 ? 532 PHE B CG 1 ATOM 3582 C CD1 . PHE A 1 476 ? 35.261 133.777 -52.992 1.00 18.14 ? 532 PHE B CD1 1 ATOM 3583 C CD2 . PHE A 1 476 ? 36.342 135.888 -53.174 1.00 18.23 ? 532 PHE B CD2 1 ATOM 3584 C CE1 . PHE A 1 476 ? 35.803 133.611 -51.730 1.00 23.97 ? 532 PHE B CE1 1 ATOM 3585 C CE2 . PHE A 1 476 ? 36.880 135.731 -51.924 1.00 16.28 ? 532 PHE B CE2 1 ATOM 3586 C CZ . PHE A 1 476 ? 36.609 134.590 -51.197 1.00 24.40 ? 532 PHE B CZ 1 ATOM 3587 N N . SER A 1 477 ? 33.953 133.294 -58.053 1.00 10.15 ? 533 SER B N 1 ATOM 3588 C CA . SER A 1 477 ? 33.384 133.586 -59.358 1.00 8.85 ? 533 SER B CA 1 ATOM 3589 C C . SER A 1 477 ? 31.860 133.596 -59.430 1.00 11.78 ? 533 SER B C 1 ATOM 3590 O O . SER A 1 477 ? 31.173 133.016 -58.597 1.00 6.77 ? 533 SER B O 1 ATOM 3591 C CB . SER A 1 477 ? 33.950 132.647 -60.423 1.00 11.20 ? 533 SER B CB 1 ATOM 3592 O OG . SER A 1 477 ? 33.782 131.287 -60.083 1.00 10.83 ? 533 SER B OG 1 ATOM 3593 N N . ASP A 1 478 ? 31.352 134.294 -60.441 1.00 15.57 ? 534 ASP B N 1 ATOM 3594 C CA . ASP A 1 478 ? 29.924 134.405 -60.695 1.00 8.20 ? 534 ASP B CA 1 ATOM 3595 C C . ASP A 1 478 ? 29.207 135.006 -59.496 1.00 10.35 ? 534 ASP B C 1 ATOM 3596 O O . ASP A 1 478 ? 28.332 134.391 -58.889 1.00 9.71 ? 534 ASP B O 1 ATOM 3597 C CB . ASP A 1 478 ? 29.349 133.040 -61.077 1.00 6.58 ? 534 ASP B CB 1 ATOM 3598 C CG . ASP A 1 478 ? 27.967 133.131 -61.663 1.00 18.42 ? 534 ASP B CG 1 ATOM 3599 O OD1 . ASP A 1 478 ? 27.493 134.265 -61.908 1.00 24.61 ? 534 ASP B OD1 1 ATOM 3600 O OD2 . ASP A 1 478 ? 27.358 132.058 -61.888 1.00 22.78 ? 534 ASP B OD2 1 ATOM 3601 N N . ASN A 1 479 ? 29.583 136.243 -59.189 1.00 19.44 ? 535 ASN B N 1 ATOM 3602 C CA . ASN A 1 479 ? 28.966 137.029 -58.136 1.00 7.65 ? 535 ASN B CA 1 ATOM 3603 C C . ASN A 1 479 ? 28.842 138.450 -58.656 1.00 13.38 ? 535 ASN B C 1 ATOM 3604 O O . ASN A 1 479 ? 28.991 138.688 -59.860 1.00 16.54 ? 535 ASN B O 1 ATOM 3605 C CB . ASN A 1 479 ? 29.808 136.995 -56.849 1.00 8.06 ? 535 ASN B CB 1 ATOM 3606 C CG . ASN A 1 479 ? 29.531 135.753 -55.988 1.00 21.33 ? 535 ASN B CG 1 ATOM 3607 O OD1 . ASN A 1 479 ? 28.488 135.651 -55.350 1.00 16.13 ? 535 ASN B OD1 1 ATOM 3608 N ND2 . ASN A 1 479 ? 30.479 134.824 -55.952 1.00 7.50 ? 535 ASN B ND2 1 ATOM 3609 N N . ALA A 1 480 ? 28.473 139.365 -57.768 1.00 9.04 ? 536 ALA B N 1 ATOM 3610 C CA . ALA A 1 480 ? 28.457 140.815 -58.021 1.00 12.46 ? 536 ALA B CA 1 ATOM 3611 C C . ALA A 1 480 ? 29.611 141.627 -57.417 1.00 16.00 ? 536 ALA B C 1 ATOM 3612 O O . ALA A 1 480 ? 29.438 142.822 -57.191 1.00 17.89 ? 536 ALA B O 1 ATOM 3613 C CB . ALA A 1 480 ? 27.110 141.438 -57.681 1.00 12.75 ? 536 ALA B CB 1 ATOM 3614 N N . LEU A 1 481 ? 30.696 140.972 -57.001 1.00 15.69 ? 537 LEU B N 1 ATOM 3615 C CA . LEU A 1 481 ? 31.812 141.656 -56.319 1.00 21.39 ? 537 LEU B CA 1 ATOM 3616 C C . LEU A 1 481 ? 32.355 142.838 -57.120 1.00 23.15 ? 537 LEU B C 1 ATOM 3617 O O . LEU A 1 481 ? 32.302 142.833 -58.352 1.00 22.93 ? 537 LEU B O 1 ATOM 3618 C CB . LEU A 1 481 ? 32.968 140.688 -56.039 1.00 10.92 ? 537 LEU B CB 1 ATOM 3619 C CG . LEU A 1 481 ? 32.750 139.561 -55.035 1.00 16.91 ? 537 LEU B CG 1 ATOM 3620 C CD1 . LEU A 1 481 ? 34.020 138.734 -54.853 1.00 11.22 ? 537 LEU B CD1 1 ATOM 3621 C CD2 . LEU A 1 481 ? 32.250 140.096 -53.712 1.00 10.71 ? 537 LEU B CD2 1 ATOM 3622 N N . SER A 1 482 ? 32.874 143.852 -56.423 1.00 26.27 ? 538 SER B N 1 ATOM 3623 C CA . SER A 1 482 ? 33.367 145.058 -57.100 1.00 24.41 ? 538 SER B CA 1 ATOM 3624 C C . SER A 1 482 ? 34.549 145.788 -56.450 1.00 18.78 ? 538 SER B C 1 ATOM 3625 O O . SER A 1 482 ? 35.194 145.295 -55.530 1.00 19.30 ? 538 SER B O 1 ATOM 3626 C CB . SER A 1 482 ? 32.229 146.058 -57.355 1.00 28.57 ? 538 SER B CB 1 ATOM 3627 O OG . SER A 1 482 ? 31.783 146.643 -56.142 1.00 36.10 ? 538 SER B OG 1 ATOM 3628 N N . SER A 1 483 ? 34.784 146.989 -56.966 1.00 23.33 ? 539 SER B N 1 ATOM 3629 C CA . SER A 1 483 ? 35.981 147.792 -56.747 1.00 28.06 ? 539 SER B CA 1 ATOM 3630 C C . SER A 1 483 ? 37.264 147.058 -57.134 1.00 29.04 ? 539 SER B C 1 ATOM 3631 O O . SER A 1 483 ? 37.247 146.208 -58.017 1.00 31.44 ? 539 SER B O 1 ATOM 3632 C CB . SER A 1 483 ? 36.051 148.265 -55.292 1.00 30.18 ? 539 SER B CB 1 ATOM 3633 O OG . SER A 1 483 ? 36.580 149.578 -55.216 1.00 32.15 ? 539 SER B OG 1 ATOM 3634 N N . THR A 1 484 ? 38.354 147.307 -56.417 1.00 30.63 ? 540 THR B N 1 ATOM 3635 C CA . THR A 1 484 ? 39.650 146.831 -56.890 1.00 35.06 ? 540 THR B CA 1 ATOM 3636 C C . THR A 1 484 ? 40.105 145.579 -56.184 1.00 37.13 ? 540 THR B C 1 ATOM 3637 O O . THR A 1 484 ? 39.841 145.378 -54.991 1.00 48.97 ? 540 THR B O 1 ATOM 3638 C CB . THR A 1 484 ? 40.799 147.880 -56.745 1.00 49.67 ? 540 THR B CB 1 ATOM 3639 O OG1 . THR A 1 484 ? 41.156 148.032 -55.362 1.00 43.39 ? 540 THR B OG1 1 ATOM 3640 C CG2 . THR A 1 484 ? 40.421 149.223 -57.365 1.00 18.07 ? 540 THR B CG2 1 ATOM 3641 N N . LEU A 1 485 ? 40.790 144.736 -56.945 1.00 24.09 ? 541 LEU B N 1 ATOM 3642 C CA . LEU A 1 485 ? 41.511 143.628 -56.369 1.00 27.72 ? 541 LEU B CA 1 ATOM 3643 C C . LEU A 1 485 ? 42.520 144.227 -55.388 1.00 39.92 ? 541 LEU B C 1 ATOM 3644 O O . LEU A 1 485 ? 43.393 145.002 -55.779 1.00 42.69 ? 541 LEU B O 1 ATOM 3645 C CB . LEU A 1 485 ? 42.197 142.831 -57.469 1.00 23.09 ? 541 LEU B CB 1 ATOM 3646 C CG . LEU A 1 485 ? 42.836 141.512 -57.056 1.00 27.54 ? 541 LEU B CG 1 ATOM 3647 C CD1 . LEU A 1 485 ? 41.818 140.619 -56.390 1.00 29.38 ? 541 LEU B CD1 1 ATOM 3648 C CD2 . LEU A 1 485 ? 43.424 140.833 -58.260 1.00 21.32 ? 541 LEU B CD2 1 ATOM 3649 N N . PRO A 1 486 ? 42.374 143.889 -54.096 1.00 44.83 ? 542 PRO B N 1 ATOM 3650 C CA . PRO A 1 486 ? 43.155 144.497 -53.016 1.00 42.73 ? 542 PRO B CA 1 ATOM 3651 C C . PRO A 1 486 ? 44.612 144.090 -53.089 1.00 42.33 ? 542 PRO B C 1 ATOM 3652 O O . PRO A 1 486 ? 44.912 142.921 -53.327 1.00 41.65 ? 542 PRO B O 1 ATOM 3653 C CB . PRO A 1 486 ? 42.526 143.897 -51.764 1.00 46.87 ? 542 PRO B CB 1 ATOM 3654 C CG . PRO A 1 486 ? 42.026 142.563 -52.217 1.00 49.23 ? 542 PRO B CG 1 ATOM 3655 C CD . PRO A 1 486 ? 41.490 142.822 -53.596 1.00 46.06 ? 542 PRO B CD 1 ATOM 3656 N N . PRO A 1 487 ? 45.519 145.048 -52.876 1.00 41.89 ? 543 PRO B N 1 ATOM 3657 C CA . PRO A 1 487 ? 46.954 144.751 -52.872 1.00 40.84 ? 543 PRO B CA 1 ATOM 3658 C C . PRO A 1 487 ? 47.297 143.671 -51.839 1.00 44.96 ? 543 PRO B C 1 ATOM 3659 O O . PRO A 1 487 ? 48.248 142.900 -52.030 1.00 41.14 ? 543 PRO B O 1 ATOM 3660 C CB . PRO A 1 487 ? 47.593 146.099 -52.508 1.00 33.95 ? 543 PRO B CB 1 ATOM 3661 C CG . PRO A 1 487 ? 46.488 146.938 -51.963 1.00 34.44 ? 543 PRO B CG 1 ATOM 3662 C CD . PRO A 1 487 ? 45.237 146.468 -52.611 1.00 37.99 ? 543 PRO B CD 1 ATOM 3663 N N . GLY A 1 488 ? 46.479 143.584 -50.788 1.00 45.23 ? 544 GLY B N 1 ATOM 3664 C CA . GLY A 1 488 ? 46.662 142.617 -49.717 1.00 39.95 ? 544 GLY B CA 1 ATOM 3665 C C . GLY A 1 488 ? 46.581 141.182 -50.204 1.00 37.73 ? 544 GLY B C 1 ATOM 3666 O O . GLY A 1 488 ? 46.865 140.230 -49.466 1.00 37.85 ? 544 GLY B O 1 ATOM 3667 N N . ILE A 1 489 ? 46.190 141.026 -51.462 1.00 31.99 ? 545 ILE B N 1 ATOM 3668 C CA . ILE A 1 489 ? 46.137 139.714 -52.072 1.00 31.91 ? 545 ILE B CA 1 ATOM 3669 C C . ILE A 1 489 ? 47.536 139.111 -52.061 1.00 31.69 ? 545 ILE B C 1 ATOM 3670 O O . ILE A 1 489 ? 47.695 137.893 -52.053 1.00 32.63 ? 545 ILE B O 1 ATOM 3671 C CB . ILE A 1 489 ? 45.564 139.788 -53.511 1.00 35.72 ? 545 ILE B CB 1 ATOM 3672 C CG1 . ILE A 1 489 ? 45.106 138.409 -53.980 1.00 33.84 ? 545 ILE B CG1 1 ATOM 3673 C CG2 . ILE A 1 489 ? 46.566 140.433 -54.488 1.00 30.45 ? 545 ILE B CG2 1 ATOM 3674 C CD1 . ILE A 1 489 ? 46.167 137.631 -54.736 1.00 39.82 ? 545 ILE B CD1 1 ATOM 3675 N N . GLY A 1 490 ? 48.551 139.973 -52.029 1.00 30.68 ? 546 GLY B N 1 ATOM 3676 C CA . GLY A 1 490 ? 49.927 139.515 -52.015 1.00 30.96 ? 546 GLY B CA 1 ATOM 3677 C C . GLY A 1 490 ? 50.296 138.775 -50.742 1.00 40.44 ? 546 GLY B C 1 ATOM 3678 O O . GLY A 1 490 ? 51.316 138.089 -50.688 1.00 45.05 ? 546 GLY B O 1 ATOM 3679 N N . LEU A 1 491 ? 49.468 138.900 -49.709 1.00 41.87 ? 547 LEU B N 1 ATOM 3680 C CA . LEU A 1 491 ? 49.799 138.293 -48.427 1.00 37.53 ? 547 LEU B CA 1 ATOM 3681 C C . LEU A 1 491 ? 49.492 136.812 -48.391 1.00 39.77 ? 547 LEU B C 1 ATOM 3682 O O . LEU A 1 491 ? 49.985 136.105 -47.515 1.00 44.74 ? 547 LEU B O 1 ATOM 3683 C CB . LEU A 1 491 ? 49.066 138.991 -47.290 1.00 39.02 ? 547 LEU B CB 1 ATOM 3684 C CG . LEU A 1 491 ? 49.522 140.424 -47.059 1.00 40.88 ? 547 LEU B CG 1 ATOM 3685 C CD1 . LEU A 1 491 ? 48.726 141.049 -45.931 1.00 41.49 ? 547 LEU B CD1 1 ATOM 3686 C CD2 . LEU A 1 491 ? 51.009 140.433 -46.763 1.00 34.16 ? 547 LEU B CD2 1 ATOM 3687 N N . LEU A 1 492 ? 48.694 136.322 -49.338 1.00 34.97 ? 548 LEU B N 1 ATOM 3688 C CA . LEU A 1 492 ? 48.370 134.911 -49.292 1.00 36.01 ? 548 LEU B CA 1 ATOM 3689 C C . LEU A 1 492 ? 49.438 134.235 -50.120 1.00 40.70 ? 548 LEU B C 1 ATOM 3690 O O . LEU A 1 492 ? 49.389 134.244 -51.345 1.00 42.98 ? 548 LEU B O 1 ATOM 3691 C CB . LEU A 1 492 ? 46.996 134.660 -49.915 1.00 35.89 ? 548 LEU B CB 1 ATOM 3692 C CG . LEU A 1 492 ? 45.853 135.614 -49.554 1.00 36.00 ? 548 LEU B CG 1 ATOM 3693 C CD1 . LEU A 1 492 ? 44.675 135.391 -50.479 1.00 35.41 ? 548 LEU B CD1 1 ATOM 3694 C CD2 . LEU A 1 492 ? 45.413 135.440 -48.114 1.00 34.56 ? 548 LEU B CD2 1 ATOM 3695 N N . THR A 1 493 ? 50.377 133.599 -49.434 1.00 40.19 ? 549 THR B N 1 ATOM 3696 C CA . THR A 1 493 ? 51.561 133.055 -50.081 1.00 37.96 ? 549 THR B CA 1 ATOM 3697 C C . THR A 1 493 ? 51.336 131.600 -50.432 1.00 35.71 ? 549 THR B C 1 ATOM 3698 O O . THR A 1 493 ? 52.133 130.994 -51.149 1.00 34.51 ? 549 THR B O 1 ATOM 3699 C CB . THR A 1 493 ? 52.772 133.146 -49.139 1.00 42.21 ? 549 THR B CB 1 ATOM 3700 O OG1 . THR A 1 493 ? 52.676 132.134 -48.122 1.00 40.92 ? 549 THR B OG1 1 ATOM 3701 C CG2 . THR A 1 493 ? 52.799 134.506 -48.471 1.00 46.46 ? 549 THR B CG2 1 ATOM 3702 N N . GLU A 1 494 ? 50.254 131.043 -49.893 1.00 37.31 ? 550 GLU B N 1 ATOM 3703 C CA . GLU A 1 494 ? 49.936 129.632 -50.055 1.00 33.38 ? 550 GLU B CA 1 ATOM 3704 C C . GLU A 1 494 ? 48.963 129.397 -51.199 1.00 27.08 ? 550 GLU B C 1 ATOM 3705 O O . GLU A 1 494 ? 48.730 128.264 -51.615 1.00 25.07 ? 550 GLU B O 1 ATOM 3706 C CB . GLU A 1 494 ? 49.327 129.106 -48.758 1.00 38.84 ? 550 GLU B CB 1 ATOM 3707 C CG . GLU A 1 494 ? 50.106 129.480 -47.504 1.00 47.14 ? 550 GLU B CG 1 ATOM 3708 C CD . GLU A 1 494 ? 51.342 128.622 -47.296 1.00 55.76 ? 550 GLU B CD 1 ATOM 3709 O OE1 . GLU A 1 494 ? 51.980 128.745 -46.225 1.00 63.68 ? 550 GLU B OE1 1 ATOM 3710 O OE2 . GLU A 1 494 ? 51.674 127.821 -48.194 1.00 54.75 ? 550 GLU B OE2 1 ATOM 3711 N N . LEU A 1 495 ? 48.396 130.485 -51.698 1.00 24.39 ? 551 LEU B N 1 ATOM 3712 C CA . LEU A 1 495 ? 47.302 130.416 -52.649 1.00 22.17 ? 551 LEU B CA 1 ATOM 3713 C C . LEU A 1 495 ? 47.720 129.698 -53.942 1.00 25.70 ? 551 LEU B C 1 ATOM 3714 O O . LEU A 1 495 ? 48.719 130.036 -54.579 1.00 30.14 ? 551 LEU B O 1 ATOM 3715 C CB . LEU A 1 495 ? 46.790 131.828 -52.928 1.00 27.01 ? 551 LEU B CB 1 ATOM 3716 C CG . LEU A 1 495 ? 45.539 131.992 -53.781 1.00 26.58 ? 551 LEU B CG 1 ATOM 3717 C CD1 . LEU A 1 495 ? 44.363 131.316 -53.093 1.00 28.92 ? 551 LEU B CD1 1 ATOM 3718 C CD2 . LEU A 1 495 ? 45.272 133.477 -54.008 1.00 21.31 ? 551 LEU B CD2 1 ATOM 3719 N N . THR A 1 496 ? 46.935 128.702 -54.315 1.00 30.85 ? 552 THR B N 1 ATOM 3720 C CA . THR A 1 496 ? 47.254 127.811 -55.419 1.00 33.68 ? 552 THR B CA 1 ATOM 3721 C C . THR A 1 496 ? 46.346 128.091 -56.608 1.00 32.35 ? 552 THR B C 1 ATOM 3722 O O . THR A 1 496 ? 46.814 128.344 -57.705 1.00 37.96 ? 552 THR B O 1 ATOM 3723 C CB . THR A 1 496 ? 47.154 126.348 -54.976 1.00 34.03 ? 552 THR B CB 1 ATOM 3724 O OG1 . THR A 1 496 ? 48.273 126.055 -54.131 1.00 35.00 ? 552 THR B OG1 1 ATOM 3725 C CG2 . THR A 1 496 ? 47.187 125.421 -56.166 1.00 33.79 ? 552 THR B CG2 1 ATOM 3726 N N . LYS A 1 497 ? 45.043 127.971 -56.396 1.00 30.85 ? 553 LYS B N 1 ATOM 3727 C CA . LYS A 1 497 ? 44.073 128.350 -57.403 1.00 20.08 ? 553 LYS B CA 1 ATOM 3728 C C . LYS A 1 497 ? 43.293 129.575 -56.935 1.00 18.24 ? 553 LYS B C 1 ATOM 3729 O O . LYS A 1 497 ? 42.824 129.623 -55.796 1.00 18.40 ? 553 LYS B O 1 ATOM 3730 C CB . LYS A 1 497 ? 43.143 127.176 -57.689 1.00 17.82 ? 553 LYS B CB 1 ATOM 3731 C CG . LYS A 1 497 ? 43.894 125.890 -57.991 1.00 21.98 ? 553 LYS B CG 1 ATOM 3732 C CD . LYS A 1 497 ? 42.996 124.812 -58.575 1.00 26.77 ? 553 LYS B CD 1 ATOM 3733 C CE . LYS A 1 497 ? 43.800 123.531 -58.814 1.00 28.96 ? 553 LYS B CE 1 ATOM 3734 N NZ . LYS A 1 497 ? 43.008 122.440 -59.473 1.00 30.99 ? 553 LYS B NZ 1 ATOM 3735 N N . LEU A 1 498 ? 43.179 130.570 -57.809 1.00 18.83 ? 554 LEU B N 1 ATOM 3736 C CA . LEU A 1 498 ? 42.430 131.784 -57.508 1.00 11.68 ? 554 LEU B CA 1 ATOM 3737 C C . LEU A 1 498 ? 41.489 132.098 -58.653 1.00 22.62 ? 554 LEU B C 1 ATOM 3738 O O . LEU A 1 498 ? 41.941 132.378 -59.768 1.00 21.61 ? 554 LEU B O 1 ATOM 3739 C CB . LEU A 1 498 ? 43.386 132.950 -57.332 1.00 12.63 ? 554 LEU B CB 1 ATOM 3740 C CG . LEU A 1 498 ? 42.751 134.333 -57.253 1.00 21.00 ? 554 LEU B CG 1 ATOM 3741 C CD1 . LEU A 1 498 ? 41.695 134.351 -56.163 1.00 20.87 ? 554 LEU B CD1 1 ATOM 3742 C CD2 . LEU A 1 498 ? 43.824 135.382 -56.979 1.00 13.78 ? 554 LEU B CD2 1 ATOM 3743 N N . ASN A 1 499 ? 40.185 132.055 -58.388 1.00 24.01 ? 555 ASN B N 1 ATOM 3744 C CA . ASN A 1 499 ? 39.208 132.332 -59.431 1.00 10.01 ? 555 ASN B CA 1 ATOM 3745 C C . ASN A 1 499 ? 38.179 133.390 -59.027 1.00 15.65 ? 555 ASN B C 1 ATOM 3746 O O . ASN A 1 499 ? 37.273 133.143 -58.217 1.00 16.58 ? 555 ASN B O 1 ATOM 3747 C CB . ASN A 1 499 ? 38.529 131.026 -59.839 1.00 9.20 ? 555 ASN B CB 1 ATOM 3748 C CG . ASN A 1 499 ? 37.481 131.221 -60.914 1.00 24.60 ? 555 ASN B CG 1 ATOM 3749 O OD1 . ASN A 1 499 ? 37.288 132.320 -61.428 1.00 27.01 ? 555 ASN B OD1 1 ATOM 3750 N ND2 . ASN A 1 499 ? 36.799 130.149 -61.261 1.00 8.00 ? 555 ASN B ND2 1 ATOM 3751 N N . LEU A 1 500 ? 38.352 134.566 -59.629 1.00 14.37 ? 556 LEU B N 1 ATOM 3752 C CA . LEU A 1 500 ? 37.532 135.767 -59.434 1.00 12.33 ? 556 LEU B CA 1 ATOM 3753 C C . LEU A 1 500 ? 36.571 136.112 -60.566 1.00 18.24 ? 556 LEU B C 1 ATOM 3754 O O . LEU A 1 500 ? 36.070 137.244 -60.624 1.00 17.33 ? 556 LEU B O 1 ATOM 3755 C CB . LEU A 1 500 ? 38.415 136.958 -59.127 1.00 16.09 ? 556 LEU B CB 1 ATOM 3756 C CG . LEU A 1 500 ? 39.146 136.729 -57.811 1.00 24.22 ? 556 LEU B CG 1 ATOM 3757 C CD1 . LEU A 1 500 ? 40.185 137.801 -57.629 1.00 26.15 ? 556 LEU B CD1 1 ATOM 3758 C CD2 . LEU A 1 500 ? 38.163 136.695 -56.628 1.00 22.04 ? 556 LEU B CD2 1 ATOM 3759 N N . ALA A 1 501 ? 36.417 135.196 -61.518 1.00 9.55 ? 557 ALA B N 1 ATOM 3760 C CA . ALA A 1 501 ? 35.778 135.501 -62.803 1.00 9.31 ? 557 ALA B CA 1 ATOM 3761 C C . ALA A 1 501 ? 34.301 135.848 -62.707 1.00 18.98 ? 557 ALA B C 1 ATOM 3762 O O . ALA A 1 501 ? 33.637 135.526 -61.720 1.00 13.22 ? 557 ALA B O 1 ATOM 3763 C CB . ALA A 1 501 ? 35.978 134.347 -63.795 1.00 8.93 ? 557 ALA B CB 1 ATOM 3764 N N . LYS A 1 502 ? 33.796 136.509 -63.748 1.00 20.18 ? 558 LYS B N 1 ATOM 3765 C CA . LYS A 1 502 ? 32.385 136.863 -63.834 1.00 15.55 ? 558 LYS B CA 1 ATOM 3766 C C . LYS A 1 502 ? 31.962 137.643 -62.600 1.00 12.56 ? 558 LYS B C 1 ATOM 3767 O O . LYS A 1 502 ? 31.061 137.242 -61.856 1.00 11.54 ? 558 LYS B O 1 ATOM 3768 C CB . LYS A 1 502 ? 31.505 135.632 -64.061 1.00 7.52 ? 558 LYS B CB 1 ATOM 3769 C CG . LYS A 1 502 ? 30.162 135.969 -64.656 1.00 35.43 ? 558 LYS B CG 1 ATOM 3770 C CD . LYS A 1 502 ? 29.420 134.709 -65.058 1.00 42.07 ? 558 LYS B CD 1 ATOM 3771 C CE . LYS A 1 502 ? 28.276 135.029 -66.028 1.00 50.29 ? 558 LYS B CE 1 ATOM 3772 N NZ . LYS A 1 502 ? 27.359 136.081 -65.507 1.00 49.03 ? 558 LYS B NZ 1 ATOM 3773 N N . ASN A 1 503 ? 32.681 138.735 -62.367 1.00 18.41 ? 559 ASN B N 1 ATOM 3774 C CA . ASN A 1 503 ? 32.324 139.727 -61.362 1.00 14.28 ? 559 ASN B CA 1 ATOM 3775 C C . ASN A 1 503 ? 32.372 141.135 -61.954 1.00 23.98 ? 559 ASN B C 1 ATOM 3776 O O . ASN A 1 503 ? 32.552 141.309 -63.166 1.00 33.13 ? 559 ASN B O 1 ATOM 3777 C CB . ASN A 1 503 ? 33.233 139.599 -60.138 1.00 13.81 ? 559 ASN B CB 1 ATOM 3778 C CG . ASN A 1 503 ? 32.754 138.524 -59.173 1.00 22.49 ? 559 ASN B CG 1 ATOM 3779 O OD1 . ASN A 1 503 ? 31.725 138.693 -58.531 1.00 24.85 ? 559 ASN B OD1 1 ATOM 3780 N ND2 . ASN A 1 503 ? 33.497 137.419 -59.066 1.00 9.37 ? 559 ASN B ND2 1 ATOM 3781 N N . ARG A 1 504 ? 32.150 142.127 -61.105 1.00 20.25 ? 560 ARG B N 1 ATOM 3782 C CA . ARG A 1 504 ? 32.236 143.544 -61.475 1.00 24.04 ? 560 ARG B CA 1 ATOM 3783 C C . ARG A 1 504 ? 33.548 144.248 -61.102 1.00 24.01 ? 560 ARG B C 1 ATOM 3784 O O . ARG A 1 504 ? 33.568 145.468 -60.975 1.00 29.59 ? 560 ARG B O 1 ATOM 3785 C CB . ARG A 1 504 ? 31.016 144.332 -61.002 1.00 30.57 ? 560 ARG B CB 1 ATOM 3786 C CG . ARG A 1 504 ? 29.740 143.969 -61.741 1.00 38.89 ? 560 ARG B CG 1 ATOM 3787 C CD . ARG A 1 504 ? 28.695 143.410 -60.789 1.00 50.06 ? 560 ARG B CD 1 ATOM 3788 N NE . ARG A 1 504 ? 27.457 143.036 -61.477 1.00 62.65 ? 560 ARG B NE 1 ATOM 3789 C CZ . ARG A 1 504 ? 27.229 141.851 -62.053 1.00 63.91 ? 560 ARG B CZ 1 ATOM 3790 N NH1 . ARG A 1 504 ? 28.154 140.893 -62.046 1.00 57.21 ? 560 ARG B NH1 1 ATOM 3791 N NH2 . ARG A 1 504 ? 26.064 141.624 -62.644 1.00 65.48 ? 560 ARG B NH2 1 ATOM 3792 N N . LEU A 1 505 ? 34.585 143.482 -60.776 1.00 18.03 ? 561 LEU B N 1 ATOM 3793 C CA . LEU A 1 505 ? 35.883 144.036 -60.349 1.00 18.89 ? 561 LEU B CA 1 ATOM 3794 C C . LEU A 1 505 ? 36.551 145.012 -61.364 1.00 25.79 ? 561 LEU B C 1 ATOM 3795 O O . LEU A 1 505 ? 36.443 144.828 -62.582 1.00 22.73 ? 561 LEU B O 1 ATOM 3796 C CB . LEU A 1 505 ? 36.841 142.876 -59.992 1.00 17.39 ? 561 LEU B CB 1 ATOM 3797 C CG . LEU A 1 505 ? 36.502 142.012 -58.757 1.00 22.10 ? 561 LEU B CG 1 ATOM 3798 C CD1 . LEU A 1 505 ? 37.367 140.749 -58.643 1.00 19.34 ? 561 LEU B CD1 1 ATOM 3799 C CD2 . LEU A 1 505 ? 36.628 142.823 -57.473 1.00 21.67 ? 561 LEU B CD2 1 ATOM 3800 N N . SER A 1 506 ? 37.252 146.034 -60.859 1.00 22.36 ? 562 SER B N 1 ATOM 3801 C CA . SER A 1 506 ? 37.878 147.056 -61.718 1.00 21.80 ? 562 SER B CA 1 ATOM 3802 C C . SER A 1 506 ? 39.267 147.537 -61.267 1.00 23.61 ? 562 SER B C 1 ATOM 3803 O O . SER A 1 506 ? 39.828 147.047 -60.286 1.00 21.10 ? 562 SER B O 1 ATOM 3804 C CB . SER A 1 506 ? 36.957 148.263 -61.857 1.00 22.31 ? 562 SER B CB 1 ATOM 3805 O OG . SER A 1 506 ? 36.697 148.821 -60.578 1.00 36.04 ? 562 SER B OG 1 ATOM 3806 N N . GLY A 1 507 ? 39.819 148.506 -62.000 1.00 25.58 ? 563 GLY B N 1 ATOM 3807 C CA . GLY A 1 507 ? 41.172 148.987 -61.743 1.00 21.01 ? 563 GLY B CA 1 ATOM 3808 C C . GLY A 1 507 ? 42.237 148.109 -62.386 1.00 24.02 ? 563 GLY B C 1 ATOM 3809 O O . GLY A 1 507 ? 41.910 147.267 -63.223 1.00 22.22 ? 563 GLY B O 1 ATOM 3810 N N . GLU A 1 508 ? 43.501 148.307 -62.006 1.00 29.65 ? 564 GLU B N 1 ATOM 3811 C CA . GLU A 1 508 ? 44.610 147.492 -62.508 1.00 34.90 ? 564 GLU B CA 1 ATOM 3812 C C . GLU A 1 508 ? 44.751 146.187 -61.741 1.00 36.26 ? 564 GLU B C 1 ATOM 3813 O O . GLU A 1 508 ? 44.087 145.966 -60.729 1.00 45.55 ? 564 GLU B O 1 ATOM 3814 C CB . GLU A 1 508 ? 45.937 148.237 -62.339 1.00 42.30 ? 564 GLU B CB 1 ATOM 3815 C CG . GLU A 1 508 ? 46.506 148.890 -63.579 1.00 58.69 ? 564 GLU B CG 1 ATOM 3816 C CD . GLU A 1 508 ? 45.989 150.297 -63.765 1.00 70.49 ? 564 GLU B CD 1 ATOM 3817 O OE1 . GLU A 1 508 ? 44.880 150.577 -63.256 1.00 77.09 ? 564 GLU B OE1 1 ATOM 3818 O OE2 . GLU A 1 508 ? 46.686 151.118 -64.405 1.00 68.40 ? 564 GLU B OE2 1 ATOM 3819 N N . ILE A 1 509 ? 45.669 145.350 -62.209 1.00 31.99 ? 565 ILE B N 1 ATOM 3820 C CA . ILE A 1 509 ? 46.132 144.197 -61.460 1.00 29.92 ? 565 ILE B CA 1 ATOM 3821 C C . ILE A 1 509 ? 47.283 144.686 -60.591 1.00 37.53 ? 565 ILE B C 1 ATOM 3822 O O . ILE A 1 509 ? 48.313 145.116 -61.116 1.00 43.72 ? 565 ILE B O 1 ATOM 3823 C CB . ILE A 1 509 ? 46.658 143.106 -62.404 1.00 23.69 ? 565 ILE B CB 1 ATOM 3824 C CG1 . ILE A 1 509 ? 45.541 142.584 -63.305 1.00 19.52 ? 565 ILE B CG1 1 ATOM 3825 C CG2 . ILE A 1 509 ? 47.286 141.965 -61.624 1.00 21.67 ? 565 ILE B CG2 1 ATOM 3826 C CD1 . ILE A 1 509 ? 46.055 141.699 -64.442 1.00 17.00 ? 565 ILE B CD1 1 ATOM 3827 N N . PRO A 1 510 ? 47.109 144.645 -59.260 1.00 34.35 ? 566 PRO B N 1 ATOM 3828 C CA . PRO A 1 510 ? 48.135 145.140 -58.342 1.00 33.03 ? 566 PRO B CA 1 ATOM 3829 C C . PRO A 1 510 ? 49.407 144.321 -58.471 1.00 41.35 ? 566 PRO B C 1 ATOM 3830 O O . PRO A 1 510 ? 49.326 143.102 -58.577 1.00 43.62 ? 566 PRO B O 1 ATOM 3831 C CB . PRO A 1 510 ? 47.503 144.916 -56.972 1.00 28.47 ? 566 PRO B CB 1 ATOM 3832 C CG . PRO A 1 510 ? 46.530 143.827 -57.175 1.00 29.32 ? 566 PRO B CG 1 ATOM 3833 C CD . PRO A 1 510 ? 45.960 144.085 -58.533 1.00 31.12 ? 566 PRO B CD 1 ATOM 3834 N N . ARG A 1 511 ? 50.562 144.981 -58.462 1.00 40.79 ? 567 ARG B N 1 ATOM 3835 C CA . ARG A 1 511 ? 51.825 144.298 -58.698 1.00 39.04 ? 567 ARG B CA 1 ATOM 3836 C C . ARG A 1 511 ? 52.186 143.359 -57.540 1.00 35.55 ? 567 ARG B C 1 ATOM 3837 O O . ARG A 1 511 ? 53.009 142.442 -57.688 1.00 29.86 ? 567 ARG B O 1 ATOM 3838 C CB . ARG A 1 511 ? 52.925 145.326 -58.966 1.00 45.03 ? 567 ARG B CB 1 ATOM 3839 C CG . ARG A 1 511 ? 52.556 146.312 -60.069 1.00 42.78 ? 567 ARG B CG 1 ATOM 3840 C CD . ARG A 1 511 ? 53.599 147.406 -60.268 1.00 43.52 ? 567 ARG B CD 1 ATOM 3841 N NE . ARG A 1 511 ? 53.085 148.467 -61.132 1.00 47.28 ? 567 ARG B NE 1 ATOM 3842 C CZ . ARG A 1 511 ? 53.066 148.411 -62.463 1.00 47.02 ? 567 ARG B CZ 1 ATOM 3843 N NH1 . ARG A 1 511 ? 53.536 147.343 -63.100 1.00 50.68 ? 567 ARG B NH1 1 ATOM 3844 N NH2 . ARG A 1 511 ? 52.565 149.422 -63.162 1.00 39.09 ? 567 ARG B NH2 1 ATOM 3845 N N . GLU A 1 512 ? 51.532 143.568 -56.398 1.00 37.22 ? 568 GLU B N 1 ATOM 3846 C CA . GLU A 1 512 ? 51.722 142.716 -55.225 1.00 39.42 ? 568 GLU B CA 1 ATOM 3847 C C . GLU A 1 512 ? 51.356 141.269 -55.537 1.00 42.03 ? 568 GLU B C 1 ATOM 3848 O O . GLU A 1 512 ? 51.780 140.342 -54.833 1.00 39.18 ? 568 GLU B O 1 ATOM 3849 C CB . GLU A 1 512 ? 50.886 143.226 -54.057 1.00 45.78 ? 568 GLU B CB 1 ATOM 3850 C CG . GLU A 1 512 ? 50.079 144.459 -54.382 1.00 53.07 ? 568 GLU B CG 1 ATOM 3851 C CD . GLU A 1 512 ? 50.884 145.731 -54.269 1.00 58.37 ? 568 GLU B CD 1 ATOM 3852 O OE1 . GLU A 1 512 ? 50.302 146.821 -54.442 1.00 59.84 ? 568 GLU B OE1 1 ATOM 3853 O OE2 . GLU A 1 512 ? 52.098 145.641 -54.004 1.00 63.22 ? 568 GLU B OE2 1 ATOM 3854 N N . ILE A 1 513 ? 50.595 141.085 -56.616 1.00 45.09 ? 569 ILE B N 1 ATOM 3855 C CA . ILE A 1 513 ? 50.260 139.761 -57.124 1.00 42.22 ? 569 ILE B CA 1 ATOM 3856 C C . ILE A 1 513 ? 51.508 138.890 -57.274 1.00 40.92 ? 569 ILE B C 1 ATOM 3857 O O . ILE A 1 513 ? 51.440 137.672 -57.086 1.00 42.87 ? 569 ILE B O 1 ATOM 3858 C CB . ILE A 1 513 ? 49.492 139.827 -58.482 1.00 35.17 ? 569 ILE B CB 1 ATOM 3859 C CG1 . ILE A 1 513 ? 48.854 138.477 -58.819 1.00 26.06 ? 569 ILE B CG1 1 ATOM 3860 C CG2 . ILE A 1 513 ? 50.394 140.289 -59.620 1.00 38.75 ? 569 ILE B CG2 1 ATOM 3861 C CD1 . ILE A 1 513 ? 47.480 138.308 -58.229 1.00 16.95 ? 569 ILE B CD1 1 ATOM 3862 N N . SER A 1 514 ? 52.646 139.515 -57.581 1.00 33.22 ? 570 SER B N 1 ATOM 3863 C CA . SER A 1 514 ? 53.879 138.766 -57.830 1.00 38.00 ? 570 SER B CA 1 ATOM 3864 C C . SER A 1 514 ? 54.396 138.011 -56.614 1.00 42.70 ? 570 SER B C 1 ATOM 3865 O O . SER A 1 514 ? 55.210 137.090 -56.750 1.00 41.93 ? 570 SER B O 1 ATOM 3866 C CB . SER A 1 514 ? 54.983 139.686 -58.342 1.00 38.13 ? 570 SER B CB 1 ATOM 3867 O OG . SER A 1 514 ? 55.346 140.624 -57.352 1.00 38.57 ? 570 SER B OG 1 ATOM 3868 N N . THR A 1 515 ? 53.931 138.392 -55.426 1.00 46.70 ? 571 THR B N 1 ATOM 3869 C CA . THR A 1 515 ? 54.425 137.742 -54.214 1.00 43.77 ? 571 THR B CA 1 ATOM 3870 C C . THR A 1 515 ? 53.619 136.503 -53.851 1.00 45.60 ? 571 THR B C 1 ATOM 3871 O O . THR A 1 515 ? 53.819 135.931 -52.778 1.00 52.29 ? 571 THR B O 1 ATOM 3872 C CB . THR A 1 515 ? 54.534 138.694 -53.003 1.00 41.78 ? 571 THR B CB 1 ATOM 3873 O OG1 . THR A 1 515 ? 53.244 139.209 -52.660 1.00 42.75 ? 571 THR B OG1 1 ATOM 3874 C CG2 . THR A 1 515 ? 55.475 139.841 -53.314 1.00 40.84 ? 571 THR B CG2 1 ATOM 3875 N N . CYS A 1 516 ? 52.700 136.089 -54.725 1.00 38.55 ? 572 CYS B N 1 ATOM 3876 C CA . CYS A 1 516 ? 52.010 134.838 -54.473 1.00 33.20 ? 572 CYS B CA 1 ATOM 3877 C C . CYS A 1 516 ? 52.836 133.785 -55.180 1.00 33.39 ? 572 CYS B C 1 ATOM 3878 O O . CYS A 1 516 ? 52.652 133.518 -56.367 1.00 29.57 ? 572 CYS B O 1 ATOM 3879 C CB . CYS A 1 516 ? 50.606 134.866 -55.089 1.00 26.48 ? 572 CYS B CB 1 ATOM 3880 S SG . CYS A 1 516 ? 49.444 136.123 -54.450 1.00 37.16 ? 572 CYS B SG 1 ATOM 3881 N N . ARG A 1 517 ? 53.659 133.089 -54.415 1.00 32.48 ? 573 ARG B N 1 ATOM 3882 C CA . ARG A 1 517 ? 54.711 132.295 -55.027 1.00 41.18 ? 573 ARG B CA 1 ATOM 3883 C C . ARG A 1 517 ? 54.191 130.933 -55.423 1.00 37.29 ? 573 ARG B C 1 ATOM 3884 O O . ARG A 1 517 ? 54.823 130.214 -56.192 1.00 37.61 ? 573 ARG B O 1 ATOM 3885 C CB . ARG A 1 517 ? 55.909 132.172 -54.083 1.00 50.23 ? 573 ARG B CB 1 ATOM 3886 C CG . ARG A 1 517 ? 55.545 132.216 -52.600 1.00 58.62 ? 573 ARG B CG 1 ATOM 3887 C CD . ARG A 1 517 ? 56.757 131.922 -51.734 1.00 65.66 ? 573 ARG B CD 1 ATOM 3888 N NE . ARG A 1 517 ? 56.507 132.166 -50.316 1.00 74.08 ? 573 ARG B NE 1 ATOM 3889 C CZ . ARG A 1 517 ? 56.605 133.360 -49.735 1.00 79.53 ? 573 ARG B CZ 1 ATOM 3890 N NH1 . ARG A 1 517 ? 56.932 134.426 -50.458 1.00 78.44 ? 573 ARG B NH1 1 ATOM 3891 N NH2 . ARG A 1 517 ? 56.370 133.490 -48.432 1.00 78.67 ? 573 ARG B NH2 1 ATOM 3892 N N . SER A 1 518 ? 53.031 130.579 -54.887 1.00 36.10 ? 574 SER B N 1 ATOM 3893 C CA . SER A 1 518 ? 52.473 129.254 -55.117 1.00 28.87 ? 574 SER B CA 1 ATOM 3894 C C . SER A 1 518 ? 51.418 129.177 -56.220 1.00 24.07 ? 574 SER B C 1 ATOM 3895 O O . SER A 1 518 ? 50.923 128.093 -56.522 1.00 25.91 ? 574 SER B O 1 ATOM 3896 C CB . SER A 1 518 ? 51.937 128.674 -53.812 1.00 26.98 ? 574 SER B CB 1 ATOM 3897 O OG . SER A 1 518 ? 53.005 128.234 -52.988 1.00 34.92 ? 574 SER B OG 1 ATOM 3898 N N . LEU A 1 519 ? 51.103 130.303 -56.854 1.00 25.75 ? 575 LEU B N 1 ATOM 3899 C CA . LEU A 1 519 ? 49.880 130.371 -57.656 1.00 23.41 ? 575 LEU B CA 1 ATOM 3900 C C . LEU A 1 519 ? 49.979 129.605 -58.982 1.00 21.91 ? 575 LEU B C 1 ATOM 3901 O O . LEU A 1 519 ? 50.768 129.948 -59.870 1.00 22.65 ? 575 LEU B O 1 ATOM 3902 C CB . LEU A 1 519 ? 49.545 131.834 -57.936 1.00 19.51 ? 575 LEU B CB 1 ATOM 3903 C CG . LEU A 1 519 ? 48.122 132.127 -58.390 1.00 21.50 ? 575 LEU B CG 1 ATOM 3904 C CD1 . LEU A 1 519 ? 47.148 131.409 -57.486 1.00 22.37 ? 575 LEU B CD1 1 ATOM 3905 C CD2 . LEU A 1 519 ? 47.850 133.627 -58.369 1.00 19.06 ? 575 LEU B CD2 1 ATOM 3906 N N . GLN A 1 520 ? 49.174 128.549 -59.084 1.00 19.82 ? 576 GLN B N 1 ATOM 3907 C CA . GLN A 1 520 ? 49.061 127.736 -60.292 1.00 23.88 ? 576 GLN B CA 1 ATOM 3908 C C . GLN A 1 520 ? 47.998 128.202 -61.290 1.00 21.76 ? 576 GLN B C 1 ATOM 3909 O O . GLN A 1 520 ? 48.169 128.084 -62.502 1.00 21.20 ? 576 GLN B O 1 ATOM 3910 C CB . GLN A 1 520 ? 48.903 126.250 -59.932 1.00 26.06 ? 576 GLN B CB 1 ATOM 3911 C CG . GLN A 1 520 ? 50.168 125.615 -59.313 1.00 19.45 ? 576 GLN B CG 1 ATOM 3912 C CD . GLN A 1 520 ? 49.932 124.195 -58.786 1.00 27.88 ? 576 GLN B CD 1 ATOM 3913 O OE1 . GLN A 1 520 ? 49.034 123.492 -59.242 1.00 29.86 ? 576 GLN B OE1 1 ATOM 3914 N NE2 . GLN A 1 520 ? 50.743 123.775 -57.816 1.00 35.89 ? 576 GLN B NE2 1 ATOM 3915 N N . LEU A 1 521 ? 46.884 128.706 -60.771 1.00 23.12 ? 577 LEU B N 1 ATOM 3916 C CA . LEU A 1 521 ? 45.747 129.053 -61.613 1.00 17.64 ? 577 LEU B CA 1 ATOM 3917 C C . LEU A 1 521 ? 45.259 130.438 -61.288 1.00 17.07 ? 577 LEU B C 1 ATOM 3918 O O . LEU A 1 521 ? 44.966 130.735 -60.126 1.00 18.73 ? 577 LEU B O 1 ATOM 3919 C CB . LEU A 1 521 ? 44.597 128.073 -61.388 1.00 12.68 ? 577 LEU B CB 1 ATOM 3920 C CG . LEU A 1 521 ? 43.341 128.263 -62.259 1.00 19.55 ? 577 LEU B CG 1 ATOM 3921 C CD1 . LEU A 1 521 ? 42.695 126.916 -62.580 1.00 10.18 ? 577 LEU B CD1 1 ATOM 3922 C CD2 . LEU A 1 521 ? 42.309 129.194 -61.615 1.00 10.59 ? 577 LEU B CD2 1 ATOM 3923 N N . LEU A 1 522 ? 45.120 131.281 -62.306 1.00 16.05 ? 578 LEU B N 1 ATOM 3924 C CA . LEU A 1 522 ? 44.538 132.599 -62.058 1.00 15.47 ? 578 LEU B CA 1 ATOM 3925 C C . LEU A 1 522 ? 43.450 132.895 -63.066 1.00 14.88 ? 578 LEU B C 1 ATOM 3926 O O . LEU A 1 522 ? 43.732 133.056 -64.239 1.00 14.91 ? 578 LEU B O 1 ATOM 3927 C CB . LEU A 1 522 ? 45.614 133.687 -62.114 1.00 13.90 ? 578 LEU B CB 1 ATOM 3928 C CG . LEU A 1 522 ? 45.113 135.131 -62.028 1.00 16.40 ? 578 LEU B CG 1 ATOM 3929 C CD1 . LEU A 1 522 ? 44.469 135.396 -60.675 1.00 17.08 ? 578 LEU B CD1 1 ATOM 3930 C CD2 . LEU A 1 522 ? 46.228 136.131 -62.296 1.00 15.09 ? 578 LEU B CD2 1 ATOM 3931 N N . ASN A 1 523 ? 42.206 132.988 -62.614 1.00 17.89 ? 579 ASN B N 1 ATOM 3932 C CA . ASN A 1 523 ? 41.137 133.367 -63.518 1.00 11.17 ? 579 ASN B CA 1 ATOM 3933 C C . ASN A 1 523 ? 40.533 134.718 -63.145 1.00 11.84 ? 579 ASN B C 1 ATOM 3934 O O . ASN A 1 523 ? 39.794 134.832 -62.169 1.00 11.73 ? 579 ASN B O 1 ATOM 3935 C CB . ASN A 1 523 ? 40.052 132.298 -63.520 1.00 10.24 ? 579 ASN B CB 1 ATOM 3936 C CG . ASN A 1 523 ? 39.051 132.489 -64.641 1.00 19.63 ? 579 ASN B CG 1 ATOM 3937 O OD1 . ASN A 1 523 ? 39.011 133.538 -65.285 1.00 22.86 ? 579 ASN B OD1 1 ATOM 3938 N ND2 . ASN A 1 523 ? 38.230 131.480 -64.874 1.00 9.01 ? 579 ASN B ND2 1 ATOM 3939 N N . LEU A 1 524 ? 40.870 135.731 -63.936 1.00 13.50 ? 580 LEU B N 1 ATOM 3940 C CA . LEU A 1 524 ? 40.289 137.076 -63.860 1.00 16.47 ? 580 LEU B CA 1 ATOM 3941 C C . LEU A 1 524 ? 39.227 137.378 -64.928 1.00 17.28 ? 580 LEU B C 1 ATOM 3942 O O . LEU A 1 524 ? 38.840 138.531 -65.120 1.00 11.81 ? 580 LEU B O 1 ATOM 3943 C CB . LEU A 1 524 ? 41.378 138.134 -63.860 1.00 13.00 ? 580 LEU B CB 1 ATOM 3944 C CG . LEU A 1 524 ? 42.365 137.897 -62.723 1.00 19.33 ? 580 LEU B CG 1 ATOM 3945 C CD1 . LEU A 1 524 ? 43.394 139.006 -62.677 1.00 14.49 ? 580 LEU B CD1 1 ATOM 3946 C CD2 . LEU A 1 524 ? 41.618 137.814 -61.421 1.00 18.68 ? 580 LEU B CD2 1 ATOM 3947 N N . GLY A 1 525 ? 38.829 136.357 -65.676 1.00 13.87 ? 581 GLY B N 1 ATOM 3948 C CA . GLY A 1 525 ? 37.881 136.523 -66.769 1.00 10.54 ? 581 GLY B CA 1 ATOM 3949 C C . GLY A 1 525 ? 36.572 137.248 -66.490 1.00 15.30 ? 581 GLY B C 1 ATOM 3950 O O . GLY A 1 525 ? 36.052 137.220 -65.374 1.00 16.42 ? 581 GLY B O 1 ATOM 3951 N N . GLU A 1 526 ? 36.063 137.942 -67.508 1.00 18.27 ? 582 GLU B N 1 ATOM 3952 C CA . GLU A 1 526 ? 34.722 138.513 -67.461 1.00 9.84 ? 582 GLU B CA 1 ATOM 3953 C C . GLU A 1 526 ? 34.544 139.468 -66.264 1.00 17.45 ? 582 GLU B C 1 ATOM 3954 O O . GLU A 1 526 ? 33.677 139.293 -65.393 1.00 13.24 ? 582 GLU B O 1 ATOM 3955 C CB . GLU A 1 526 ? 33.694 137.388 -67.463 1.00 8.96 ? 582 GLU B CB 1 ATOM 3956 C CG . GLU A 1 526 ? 32.462 137.653 -68.294 1.00 30.53 ? 582 GLU B CG 1 ATOM 3957 C CD . GLU A 1 526 ? 31.622 136.394 -68.498 1.00 36.37 ? 582 GLU B CD 1 ATOM 3958 O OE1 . GLU A 1 526 ? 30.385 136.469 -68.338 1.00 44.86 ? 582 GLU B OE1 1 ATOM 3959 O OE2 . GLU A 1 526 ? 32.193 135.328 -68.823 1.00 30.28 ? 582 GLU B OE2 1 ATOM 3960 N N . ASN A 1 527 ? 35.428 140.455 -66.213 1.00 14.83 ? 583 ASN B N 1 ATOM 3961 C CA . ASN A 1 527 ? 35.331 141.551 -65.276 1.00 11.42 ? 583 ASN B CA 1 ATOM 3962 C C . ASN A 1 527 ? 35.483 142.876 -66.022 1.00 17.45 ? 583 ASN B C 1 ATOM 3963 O O . ASN A 1 527 ? 35.499 142.913 -67.254 1.00 22.02 ? 583 ASN B O 1 ATOM 3964 C CB . ASN A 1 527 ? 36.409 141.422 -64.196 1.00 30.39 ? 583 ASN B CB 1 ATOM 3965 C CG . ASN A 1 527 ? 36.008 140.472 -63.069 1.00 25.05 ? 583 ASN B CG 1 ATOM 3966 O OD1 . ASN A 1 527 ? 35.274 140.854 -62.163 1.00 26.31 ? 583 ASN B OD1 1 ATOM 3967 N ND2 . ASN A 1 527 ? 36.510 139.241 -63.113 1.00 20.81 ? 583 ASN B ND2 1 ATOM 3968 N N . ASP A 1 528 ? 35.551 143.966 -65.271 1.00 18.29 ? 584 ASP B N 1 ATOM 3969 C CA . ASP A 1 528 ? 35.879 145.294 -65.804 1.00 21.46 ? 584 ASP B CA 1 ATOM 3970 C C . ASP A 1 528 ? 37.341 145.783 -65.654 1.00 26.46 ? 584 ASP B C 1 ATOM 3971 O O . ASP A 1 528 ? 37.576 146.990 -65.637 1.00 28.20 ? 584 ASP B O 1 ATOM 3972 C CB . ASP A 1 528 ? 34.872 146.367 -65.394 1.00 31.05 ? 584 ASP B CB 1 ATOM 3973 C CG . ASP A 1 528 ? 34.835 147.518 -66.382 1.00 51.32 ? 584 ASP B CG 1 ATOM 3974 O OD1 . ASP A 1 528 ? 34.946 147.257 -67.603 1.00 57.04 ? 584 ASP B OD1 1 ATOM 3975 O OD2 . ASP A 1 528 ? 34.717 148.682 -65.943 1.00 59.45 ? 584 ASP B OD2 1 ATOM 3976 N N . PHE A 1 529 ? 38.284 144.880 -65.386 1.00 14.20 ? 585 PHE B N 1 ATOM 3977 C CA . PHE A 1 529 ? 39.699 145.254 -65.271 1.00 15.05 ? 585 PHE B CA 1 ATOM 3978 C C . PHE A 1 529 ? 40.201 146.043 -66.480 1.00 23.64 ? 585 PHE B C 1 ATOM 3979 O O . PHE A 1 529 ? 39.826 145.774 -67.645 1.00 17.99 ? 585 PHE B O 1 ATOM 3980 C CB . PHE A 1 529 ? 40.596 144.019 -65.107 1.00 20.87 ? 585 PHE B CB 1 ATOM 3981 C CG . PHE A 1 529 ? 40.444 143.306 -63.790 1.00 22.54 ? 585 PHE B CG 1 ATOM 3982 C CD1 . PHE A 1 529 ? 40.883 143.891 -62.608 1.00 19.66 ? 585 PHE B CD1 1 ATOM 3983 C CD2 . PHE A 1 529 ? 39.880 142.039 -63.738 1.00 27.25 ? 585 PHE B CD2 1 ATOM 3984 C CE1 . PHE A 1 529 ? 40.743 143.233 -61.406 1.00 22.10 ? 585 PHE B CE1 1 ATOM 3985 C CE2 . PHE A 1 529 ? 39.735 141.371 -62.525 1.00 27.18 ? 585 PHE B CE2 1 ATOM 3986 C CZ . PHE A 1 529 ? 40.166 141.963 -61.364 1.00 21.63 ? 585 PHE B CZ 1 ATOM 3987 N N . SER A 1 530 ? 41.067 147.008 -66.201 1.00 24.62 ? 586 SER B N 1 ATOM 3988 C CA . SER A 1 530 ? 41.567 147.901 -67.239 1.00 28.05 ? 586 SER B CA 1 ATOM 3989 C C . SER A 1 530 ? 43.038 148.223 -67.025 1.00 26.60 ? 586 SER B C 1 ATOM 3990 O O . SER A 1 530 ? 43.681 147.668 -66.131 1.00 25.82 ? 586 SER B O 1 ATOM 3991 C CB . SER A 1 530 ? 40.753 149.194 -67.255 1.00 32.76 ? 586 SER B CB 1 ATOM 3992 O OG . SER A 1 530 ? 40.838 149.850 -66.000 1.00 32.63 ? 586 SER B OG 1 ATOM 3993 N N . GLY A 1 531 ? 43.562 149.127 -67.850 1.00 28.96 ? 587 GLY B N 1 ATOM 3994 C CA . GLY A 1 531 ? 44.970 149.475 -67.827 1.00 24.87 ? 587 GLY B CA 1 ATOM 3995 C C . GLY A 1 531 ? 45.866 148.436 -68.483 1.00 29.69 ? 587 GLY B C 1 ATOM 3996 O O . GLY A 1 531 ? 45.472 147.739 -69.420 1.00 38.23 ? 587 GLY B O 1 ATOM 3997 N N . GLU A 1 532 ? 47.088 148.331 -67.985 1.00 27.08 ? 588 GLU B N 1 ATOM 3998 C CA . GLU A 1 532 ? 48.093 147.506 -68.625 1.00 27.96 ? 588 GLU B CA 1 ATOM 3999 C C . GLU A 1 532 ? 48.407 146.302 -67.756 1.00 28.12 ? 588 GLU B C 1 ATOM 4000 O O . GLU A 1 532 ? 48.627 146.438 -66.547 1.00 42.63 ? 588 GLU B O 1 ATOM 4001 C CB . GLU A 1 532 ? 49.354 148.334 -68.872 1.00 29.60 ? 588 GLU B CB 1 ATOM 4002 C CG . GLU A 1 532 ? 50.154 147.912 -70.087 1.00 43.37 ? 588 GLU B CG 1 ATOM 4003 C CD . GLU A 1 532 ? 51.092 149.010 -70.583 1.00 52.86 ? 588 GLU B CD 1 ATOM 4004 O OE1 . GLU A 1 532 ? 51.465 149.889 -69.772 1.00 49.80 ? 588 GLU B OE1 1 ATOM 4005 O OE2 . GLU A 1 532 ? 51.450 148.992 -71.786 1.00 53.05 ? 588 GLU B OE2 1 ATOM 4006 N N . ILE A 1 533 ? 48.412 145.125 -68.367 1.00 22.95 ? 589 ILE B N 1 ATOM 4007 C CA . ILE A 1 533 ? 48.763 143.907 -67.660 1.00 25.39 ? 589 ILE B CA 1 ATOM 4008 C C . ILE A 1 533 ? 50.163 144.095 -67.123 1.00 32.18 ? 589 ILE B C 1 ATOM 4009 O O . ILE A 1 533 ? 51.115 144.229 -67.901 1.00 26.86 ? 589 ILE B O 1 ATOM 4010 C CB . ILE A 1 533 ? 48.791 142.703 -68.599 1.00 28.26 ? 589 ILE B CB 1 ATOM 4011 C CG1 . ILE A 1 533 ? 47.447 142.530 -69.308 1.00 26.42 ? 589 ILE B CG1 1 ATOM 4012 C CG2 . ILE A 1 533 ? 49.156 141.444 -67.839 1.00 34.00 ? 589 ILE B CG2 1 ATOM 4013 C CD1 . ILE A 1 533 ? 47.525 141.661 -70.537 1.00 17.77 ? 589 ILE B CD1 1 ATOM 4014 N N . PRO A 1 534 ? 50.293 144.091 -65.789 1.00 32.93 ? 590 PRO B N 1 ATOM 4015 C CA . PRO A 1 534 ? 51.559 144.421 -65.130 1.00 38.23 ? 590 PRO B CA 1 ATOM 4016 C C . PRO A 1 534 ? 52.653 143.439 -65.526 1.00 39.29 ? 590 PRO B C 1 ATOM 4017 O O . PRO A 1 534 ? 52.360 142.311 -65.913 1.00 41.16 ? 590 PRO B O 1 ATOM 4018 C CB . PRO A 1 534 ? 51.223 144.294 -63.638 1.00 40.90 ? 590 PRO B CB 1 ATOM 4019 C CG . PRO A 1 534 ? 50.073 143.328 -63.597 1.00 38.82 ? 590 PRO B CG 1 ATOM 4020 C CD . PRO A 1 534 ? 49.270 143.632 -64.836 1.00 35.17 ? 590 PRO B CD 1 ATOM 4021 N N . ASP A 1 535 ? 53.901 143.880 -65.449 1.00 38.80 ? 591 ASP B N 1 ATOM 4022 C CA . ASP A 1 535 ? 55.035 143.032 -65.764 1.00 37.41 ? 591 ASP B CA 1 ATOM 4023 C C . ASP A 1 535 ? 55.179 141.932 -64.696 1.00 37.89 ? 591 ASP B C 1 ATOM 4024 O O . ASP A 1 535 ? 55.551 140.795 -65.002 1.00 33.09 ? 591 ASP B O 1 ATOM 4025 C CB . ASP A 1 535 ? 56.289 143.905 -65.849 1.00 45.38 ? 591 ASP B CB 1 ATOM 4026 C CG . ASP A 1 535 ? 57.341 143.345 -66.794 1.00 56.87 ? 591 ASP B CG 1 ATOM 4027 O OD1 . ASP A 1 535 ? 57.180 143.468 -68.037 1.00 53.23 ? 591 ASP B OD1 1 ATOM 4028 O OD2 . ASP A 1 535 ? 58.346 142.805 -66.277 1.00 63.55 ? 591 ASP B OD2 1 ATOM 4029 N N . GLU A 1 536 ? 54.850 142.274 -63.449 1.00 44.27 ? 592 GLU B N 1 ATOM 4030 C CA . GLU A 1 536 ? 55.001 141.366 -62.307 1.00 47.22 ? 592 GLU B CA 1 ATOM 4031 C C . GLU A 1 536 ? 54.072 140.158 -62.385 1.00 47.82 ? 592 GLU B C 1 ATOM 4032 O O . GLU A 1 536 ? 54.199 139.196 -61.629 1.00 50.86 ? 592 GLU B O 1 ATOM 4033 C CB . GLU A 1 536 ? 54.768 142.115 -60.990 1.00 45.54 ? 592 GLU B CB 1 ATOM 4034 C CG . GLU A 1 536 ? 55.711 143.277 -60.744 1.00 46.72 ? 592 GLU B CG 1 ATOM 4035 C CD . GLU A 1 536 ? 55.255 144.551 -61.422 1.00 49.74 ? 592 GLU B CD 1 ATOM 4036 O OE1 . GLU A 1 536 ? 54.269 144.497 -62.189 1.00 46.36 ? 592 GLU B OE1 1 ATOM 4037 O OE2 . GLU A 1 536 ? 55.878 145.607 -61.185 1.00 56.60 ? 592 GLU B OE2 1 ATOM 4038 N N . LEU A 1 537 ? 53.141 140.207 -63.319 1.00 43.13 ? 593 LEU B N 1 ATOM 4039 C CA . LEU A 1 537 ? 52.267 139.082 -63.523 1.00 36.15 ? 593 LEU B CA 1 ATOM 4040 C C . LEU A 1 537 ? 53.036 137.952 -64.234 1.00 36.29 ? 593 LEU B C 1 ATOM 4041 O O . LEU A 1 537 ? 52.722 136.771 -64.078 1.00 34.48 ? 593 LEU B O 1 ATOM 4042 C CB . LEU A 1 537 ? 51.007 139.534 -64.258 1.00 37.31 ? 593 LEU B CB 1 ATOM 4043 C CG . LEU A 1 537 ? 49.977 138.432 -64.440 1.00 31.38 ? 593 LEU B CG 1 ATOM 4044 C CD1 . LEU A 1 537 ? 49.638 137.751 -63.115 1.00 30.74 ? 593 LEU B CD1 1 ATOM 4045 C CD2 . LEU A 1 537 ? 48.752 139.025 -65.069 1.00 29.27 ? 593 LEU B CD2 1 ATOM 4046 N N . GLY A 1 538 ? 54.075 138.328 -64.972 1.00 41.82 ? 594 GLY B N 1 ATOM 4047 C CA . GLY A 1 538 ? 55.000 137.364 -65.520 1.00 42.51 ? 594 GLY B CA 1 ATOM 4048 C C . GLY A 1 538 ? 55.832 136.753 -64.433 1.00 47.03 ? 594 GLY B C 1 ATOM 4049 O O . GLY A 1 538 ? 56.386 135.658 -64.629 1.00 47.41 ? 594 GLY B O 1 ATOM 4050 N N . GLN A 1 539 ? 55.898 137.429 -63.291 1.00 48.02 ? 595 GLN B N 1 ATOM 4051 C CA . GLN A 1 539 ? 56.909 137.121 -62.304 1.00 46.35 ? 595 GLN B CA 1 ATOM 4052 C C . GLN A 1 539 ? 56.568 135.856 -61.454 1.00 50.37 ? 595 GLN B C 1 ATOM 4053 O O . GLN A 1 539 ? 57.241 135.574 -60.456 1.00 50.42 ? 595 GLN B O 1 ATOM 4054 C CB . GLN A 1 539 ? 57.174 138.331 -61.420 1.00 55.33 ? 595 GLN B CB 1 ATOM 4055 C CG . GLN A 1 539 ? 58.632 138.629 -61.139 1.00 58.16 ? 595 GLN B CG 1 ATOM 4056 C CD . GLN A 1 539 ? 58.923 140.094 -61.276 1.00 60.52 ? 595 GLN B CD 1 ATOM 4057 O OE1 . GLN A 1 539 ? 58.124 140.906 -60.816 1.00 60.25 ? 595 GLN B OE1 1 ATOM 4058 N NE2 . GLN A 1 539 ? 60.017 140.453 -61.989 1.00 60.31 ? 595 GLN B NE2 1 ATOM 4059 N N . ILE A 1 540 ? 55.527 135.098 -61.830 1.00 46.34 ? 596 ILE B N 1 ATOM 4060 C CA . ILE A 1 540 ? 55.068 133.911 -61.056 1.00 39.22 ? 596 ILE B CA 1 ATOM 4061 C C . ILE A 1 540 ? 55.264 132.600 -61.834 1.00 45.73 ? 596 ILE B C 1 ATOM 4062 O O . ILE A 1 540 ? 54.336 132.104 -62.486 1.00 49.51 ? 596 ILE B O 1 ATOM 4063 C CB . ILE A 1 540 ? 53.561 133.998 -60.710 1.00 33.44 ? 596 ILE B CB 1 ATOM 4064 C CG1 . ILE A 1 540 ? 53.191 135.448 -60.431 1.00 29.25 ? 596 ILE B CG1 1 ATOM 4065 C CG2 . ILE A 1 540 ? 53.134 133.017 -59.560 1.00 27.80 ? 596 ILE B CG2 1 ATOM 4066 C CD1 . ILE A 1 540 ? 51.729 135.701 -60.450 1.00 25.36 ? 596 ILE B CD1 1 ATOM 4067 N N . PRO A 1 541 ? 56.474 132.030 -61.776 1.00 47.18 ? 597 PRO B N 1 ATOM 4068 C CA . PRO A 1 541 ? 56.833 130.831 -62.546 1.00 45.86 ? 597 PRO B CA 1 ATOM 4069 C C . PRO A 1 541 ? 56.002 129.606 -62.186 1.00 43.47 ? 597 PRO B C 1 ATOM 4070 O O . PRO A 1 541 ? 55.987 128.633 -62.950 1.00 39.86 ? 597 PRO B O 1 ATOM 4071 C CB . PRO A 1 541 ? 58.295 130.583 -62.151 1.00 48.89 ? 597 PRO B CB 1 ATOM 4072 C CG . PRO A 1 541 ? 58.771 131.872 -61.594 1.00 49.68 ? 597 PRO B CG 1 ATOM 4073 C CD . PRO A 1 541 ? 57.590 132.501 -60.944 1.00 48.24 ? 597 PRO B CD 1 ATOM 4074 N N . SER A 1 542 ? 55.338 129.639 -61.032 1.00 40.99 ? 598 SER B N 1 ATOM 4075 C CA . SER A 1 542 ? 54.469 128.532 -60.648 1.00 31.37 ? 598 SER B CA 1 ATOM 4076 C C . SER A 1 542 ? 53.219 128.479 -61.523 1.00 27.73 ? 598 SER B C 1 ATOM 4077 O O . SER A 1 542 ? 52.599 127.423 -61.627 1.00 28.30 ? 598 SER B O 1 ATOM 4078 C CB . SER A 1 542 ? 54.104 128.570 -59.157 1.00 31.33 ? 598 SER B CB 1 ATOM 4079 O OG . SER A 1 542 ? 53.448 129.776 -58.799 1.00 33.72 ? 598 SER B OG 1 ATOM 4080 N N . LEU A 1 543 ? 52.859 129.600 -62.162 1.00 32.25 ? 599 LEU B N 1 ATOM 4081 C CA . LEU A 1 543 ? 51.677 129.617 -63.034 1.00 29.49 ? 599 LEU B CA 1 ATOM 4082 C C . LEU A 1 543 ? 51.846 128.565 -64.108 1.00 19.82 ? 599 LEU B C 1 ATOM 4083 O O . LEU A 1 543 ? 52.720 128.662 -64.950 1.00 28.72 ? 599 LEU B O 1 ATOM 4084 C CB . LEU A 1 543 ? 51.489 130.993 -63.678 1.00 32.00 ? 599 LEU B CB 1 ATOM 4085 C CG . LEU A 1 543 ? 50.574 131.935 -62.895 1.00 30.02 ? 599 LEU B CG 1 ATOM 4086 C CD1 . LEU A 1 543 ? 50.488 133.304 -63.544 1.00 28.96 ? 599 LEU B CD1 1 ATOM 4087 C CD2 . LEU A 1 543 ? 49.206 131.298 -62.800 1.00 27.81 ? 599 LEU B CD2 1 ATOM 4088 N N . ALA A 1 544 ? 50.957 127.585 -64.073 1.00 20.81 ? 600 ALA B N 1 ATOM 4089 C CA . ALA A 1 544 ? 51.114 126.325 -64.786 1.00 26.56 ? 600 ALA B CA 1 ATOM 4090 C C . ALA A 1 544 ? 49.822 125.921 -65.476 1.00 33.40 ? 600 ALA B C 1 ATOM 4091 O O . ALA A 1 544 ? 49.788 125.691 -66.690 1.00 38.37 ? 600 ALA B O 1 ATOM 4092 C CB . ALA A 1 544 ? 51.606 125.232 -63.851 1.00 25.94 ? 600 ALA B CB 1 ATOM 4093 N N . ILE A 1 545 ? 48.762 125.805 -64.676 1.00 29.96 ? 601 ILE B N 1 ATOM 4094 C CA . ILE A 1 545 ? 47.491 125.265 -65.147 1.00 25.44 ? 601 ILE B CA 1 ATOM 4095 C C . ILE A 1 545 ? 46.804 126.204 -66.147 1.00 27.26 ? 601 ILE B C 1 ATOM 4096 O O . ILE A 1 545 ? 46.682 125.861 -67.321 1.00 40.30 ? 601 ILE B O 1 ATOM 4097 C CB . ILE A 1 545 ? 46.543 124.989 -63.975 1.00 24.93 ? 601 ILE B CB 1 ATOM 4098 C CG1 . ILE A 1 545 ? 47.145 123.942 -63.029 1.00 29.66 ? 601 ILE B CG1 1 ATOM 4099 C CG2 . ILE A 1 545 ? 45.209 124.523 -64.479 1.00 18.09 ? 601 ILE B CG2 1 ATOM 4100 C CD1 . ILE A 1 545 ? 46.328 123.714 -61.761 1.00 17.69 ? 601 ILE B CD1 1 ATOM 4101 N N . SER A 1 546 ? 46.360 127.376 -65.704 1.00 20.89 ? 602 SER B N 1 ATOM 4102 C CA . SER A 1 546 ? 45.834 128.373 -66.635 1.00 14.93 ? 602 SER B CA 1 ATOM 4103 C C . SER A 1 546 ? 45.887 129.809 -66.118 1.00 17.70 ? 602 SER B C 1 ATOM 4104 O O . SER A 1 546 ? 45.893 130.076 -64.907 1.00 17.30 ? 602 SER B O 1 ATOM 4105 C CB . SER A 1 546 ? 44.399 128.047 -67.038 1.00 15.97 ? 602 SER B CB 1 ATOM 4106 O OG . SER A 1 546 ? 43.487 128.528 -66.067 1.00 26.97 ? 602 SER B OG 1 ATOM 4107 N N . LEU A 1 547 ? 45.899 130.734 -67.068 1.00 22.88 ? 603 LEU B N 1 ATOM 4108 C CA . LEU A 1 547 ? 45.853 132.157 -66.785 1.00 19.17 ? 603 LEU B CA 1 ATOM 4109 C C . LEU A 1 547 ? 44.782 132.740 -67.695 1.00 16.53 ? 603 LEU B C 1 ATOM 4110 O O . LEU A 1 547 ? 44.935 132.739 -68.920 1.00 20.18 ? 603 LEU B O 1 ATOM 4111 C CB . LEU A 1 547 ? 47.215 132.773 -67.104 1.00 21.37 ? 603 LEU B CB 1 ATOM 4112 C CG . LEU A 1 547 ? 47.377 134.287 -67.123 1.00 15.08 ? 603 LEU B CG 1 ATOM 4113 C CD1 . LEU A 1 547 ? 46.882 134.887 -65.835 1.00 22.31 ? 603 LEU B CD1 1 ATOM 4114 C CD2 . LEU A 1 547 ? 48.840 134.640 -67.359 1.00 16.14 ? 603 LEU B CD2 1 ATOM 4115 N N . ASN A 1 548 ? 43.691 133.223 -67.107 1.00 15.28 ? 604 ASN B N 1 ATOM 4116 C CA . ASN A 1 548 ? 42.570 133.722 -67.893 1.00 12.03 ? 604 ASN B CA 1 ATOM 4117 C C . ASN A 1 548 ? 42.309 135.191 -67.552 1.00 16.41 ? 604 ASN B C 1 ATOM 4118 O O . ASN A 1 548 ? 41.877 135.530 -66.445 1.00 13.91 ? 604 ASN B O 1 ATOM 4119 C CB . ASN A 1 548 ? 41.350 132.835 -67.679 1.00 11.07 ? 604 ASN B CB 1 ATOM 4120 C CG . ASN A 1 548 ? 40.225 133.127 -68.639 1.00 14.44 ? 604 ASN B CG 1 ATOM 4121 O OD1 . ASN A 1 548 ? 40.175 134.203 -69.253 1.00 15.04 ? 604 ASN B OD1 1 ATOM 4122 N ND2 . ASN A 1 548 ? 39.281 132.165 -68.755 1.00 12.71 ? 604 ASN B ND2 1 ATOM 4123 N N . LEU A 1 549 ? 42.677 136.053 -68.503 1.00 17.06 ? 605 LEU B N 1 ATOM 4124 C CA . LEU A 1 549 ? 42.474 137.494 -68.431 1.00 13.26 ? 605 LEU B CA 1 ATOM 4125 C C . LEU A 1 549 ? 41.350 138.017 -69.318 1.00 17.48 ? 605 LEU B C 1 ATOM 4126 O O . LEU A 1 549 ? 41.202 139.228 -69.470 1.00 19.20 ? 605 LEU B O 1 ATOM 4127 C CB . LEU A 1 549 ? 43.781 138.245 -68.689 1.00 14.26 ? 605 LEU B CB 1 ATOM 4128 C CG . LEU A 1 549 ? 44.922 138.027 -67.681 1.00 15.92 ? 605 LEU B CG 1 ATOM 4129 C CD1 . LEU A 1 549 ? 46.131 138.845 -68.072 1.00 16.65 ? 605 LEU B CD1 1 ATOM 4130 C CD2 . LEU A 1 549 ? 44.521 138.337 -66.222 1.00 14.74 ? 605 LEU B CD2 1 ATOM 4131 N N . SER A 1 550 ? 40.607 137.118 -69.956 1.00 15.67 ? 606 SER B N 1 ATOM 4132 C CA . SER A 1 550 ? 39.727 137.520 -71.054 1.00 15.35 ? 606 SER B CA 1 ATOM 4133 C C . SER A 1 550 ? 38.510 138.327 -70.611 1.00 18.30 ? 606 SER B C 1 ATOM 4134 O O . SER A 1 550 ? 38.269 138.513 -69.420 1.00 20.28 ? 606 SER B O 1 ATOM 4135 C CB . SER A 1 550 ? 39.224 136.284 -71.788 1.00 18.99 ? 606 SER B CB 1 ATOM 4136 O OG . SER A 1 550 ? 38.200 135.652 -71.030 1.00 20.64 ? 606 SER B OG 1 ATOM 4137 N N . CYS A 1 551 ? 37.743 138.782 -71.597 1.00 21.19 ? 607 CYS B N 1 ATOM 4138 C CA . CYS A 1 551 ? 36.547 139.603 -71.384 1.00 17.15 ? 607 CYS B CA 1 ATOM 4139 C C . CYS A 1 551 ? 36.748 140.714 -70.351 1.00 18.85 ? 607 CYS B C 1 ATOM 4140 O O . CYS A 1 551 ? 35.987 140.866 -69.394 1.00 20.49 ? 607 CYS B O 1 ATOM 4141 C CB . CYS A 1 551 ? 35.335 138.734 -71.098 1.00 10.18 ? 607 CYS B CB 1 ATOM 4142 S SG . CYS A 1 551 ? 35.218 137.375 -72.283 1.00 15.58 ? 607 CYS B SG 1 ATOM 4143 N N . ASN A 1 552 ? 37.813 141.473 -70.545 1.00 20.48 ? 608 ASN B N 1 ATOM 4144 C CA . ASN A 1 552 ? 38.043 142.674 -69.767 1.00 21.62 ? 608 ASN B CA 1 ATOM 4145 C C . ASN A 1 552 ? 38.272 143.846 -70.696 1.00 21.56 ? 608 ASN B C 1 ATOM 4146 O O . ASN A 1 552 ? 37.982 143.769 -71.883 1.00 32.77 ? 608 ASN B O 1 ATOM 4147 C CB . ASN A 1 552 ? 39.227 142.508 -68.818 1.00 24.30 ? 608 ASN B CB 1 ATOM 4148 C CG . ASN A 1 552 ? 38.871 141.717 -67.581 1.00 23.39 ? 608 ASN B CG 1 ATOM 4149 O OD1 . ASN A 1 552 ? 38.194 142.222 -66.692 1.00 25.37 ? 608 ASN B OD1 1 ATOM 4150 N ND2 . ASN A 1 552 ? 39.339 140.474 -67.508 1.00 18.68 ? 608 ASN B ND2 1 ATOM 4151 N N . ARG A 1 553 ? 38.697 144.958 -70.116 1.00 23.48 ? 609 ARG B N 1 ATOM 4152 C CA . ARG A 1 553 ? 39.165 146.141 -70.843 1.00 15.01 ? 609 ARG B CA 1 ATOM 4153 C C . ARG A 1 553 ? 40.678 146.397 -70.957 1.00 20.39 ? 609 ARG B C 1 ATOM 4154 O O . ARG A 1 553 ? 41.080 147.553 -71.048 1.00 20.93 ? 609 ARG B O 1 ATOM 4155 C CB . ARG A 1 553 ? 38.349 147.392 -70.522 1.00 15.19 ? 609 ARG B CB 1 ATOM 4156 C CG . ARG A 1 553 ? 36.950 147.342 -71.153 1.00 19.47 ? 609 ARG B CG 1 ATOM 4157 C CD . ARG A 1 553 ? 36.114 148.575 -70.830 1.00 29.94 ? 609 ARG B CD 1 ATOM 4158 N NE . ARG A 1 553 ? 36.092 148.902 -69.399 1.00 37.73 ? 609 ARG B NE 1 ATOM 4159 C CZ . ARG A 1 553 ? 36.756 149.918 -68.856 1.00 46.80 ? 609 ARG B CZ 1 ATOM 4160 N NH1 . ARG A 1 553 ? 37.498 150.710 -69.618 1.00 51.83 ? 609 ARG B NH1 1 ATOM 4161 N NH2 . ARG A 1 553 ? 36.678 150.150 -67.552 1.00 52.13 ? 609 ARG B NH2 1 ATOM 4162 N N . PHE A 1 554 ? 41.511 145.376 -70.763 1.00 21.04 ? 610 PHE B N 1 ATOM 4163 C CA . PHE A 1 554 ? 42.970 145.559 -70.800 1.00 16.71 ? 610 PHE B CA 1 ATOM 4164 C C . PHE A 1 554 ? 43.461 146.228 -72.079 1.00 25.57 ? 610 PHE B C 1 ATOM 4165 O O . PHE A 1 554 ? 42.893 146.023 -73.168 1.00 26.26 ? 610 PHE B O 1 ATOM 4166 C CB . PHE A 1 554 ? 43.696 144.217 -70.666 1.00 16.54 ? 610 PHE B CB 1 ATOM 4167 C CG . PHE A 1 554 ? 43.564 143.582 -69.312 1.00 27.02 ? 610 PHE B CG 1 ATOM 4168 C CD1 . PHE A 1 554 ? 44.188 144.144 -68.203 1.00 31.20 ? 610 PHE B CD1 1 ATOM 4169 C CD2 . PHE A 1 554 ? 42.835 142.417 -69.145 1.00 23.60 ? 610 PHE B CD2 1 ATOM 4170 C CE1 . PHE A 1 554 ? 44.074 143.565 -66.960 1.00 28.75 ? 610 PHE B CE1 1 ATOM 4171 C CE2 . PHE A 1 554 ? 42.709 141.836 -67.901 1.00 23.63 ? 610 PHE B CE2 1 ATOM 4172 C CZ . PHE A 1 554 ? 43.330 142.413 -66.805 1.00 27.08 ? 610 PHE B CZ 1 ATOM 4173 N N . VAL A 1 555 ? 44.515 147.033 -71.944 1.00 20.43 ? 611 VAL B N 1 ATOM 4174 C CA . VAL A 1 555 ? 45.181 147.634 -73.105 1.00 18.85 ? 611 VAL B CA 1 ATOM 4175 C C . VAL A 1 555 ? 46.700 147.538 -73.038 1.00 24.65 ? 611 VAL B C 1 ATOM 4176 O O . VAL A 1 555 ? 47.270 146.999 -72.079 1.00 31.43 ? 611 VAL B O 1 ATOM 4177 C CB . VAL A 1 555 ? 44.807 149.109 -73.292 1.00 19.30 ? 611 VAL B CB 1 ATOM 4178 C CG1 . VAL A 1 555 ? 43.291 149.257 -73.427 1.00 18.53 ? 611 VAL B CG1 1 ATOM 4179 C CG2 . VAL A 1 555 ? 45.370 149.954 -72.148 1.00 20.00 ? 611 VAL B CG2 1 ATOM 4180 N N . GLY A 1 556 ? 47.351 148.085 -74.060 1.00 22.27 ? 612 GLY B N 1 ATOM 4181 C CA . GLY A 1 556 ? 48.793 147.970 -74.203 1.00 28.81 ? 612 GLY B CA 1 ATOM 4182 C C . GLY A 1 556 ? 49.194 146.593 -74.701 1.00 31.08 ? 612 GLY B C 1 ATOM 4183 O O . GLY A 1 556 ? 48.347 145.808 -75.122 1.00 32.55 ? 612 GLY B O 1 ATOM 4184 N N . GLU A 1 557 ? 50.485 146.288 -74.648 1.00 29.99 ? 613 GLU B N 1 ATOM 4185 C CA . GLU A 1 557 ? 50.968 145.035 -75.201 1.00 21.40 ? 613 GLU B CA 1 ATOM 4186 C C . GLU A 1 557 ? 51.057 143.911 -74.180 1.00 20.98 ? 613 GLU B C 1 ATOM 4187 O O . GLU A 1 557 ? 50.878 144.122 -72.978 1.00 43.54 ? 613 GLU B O 1 ATOM 4188 C CB . GLU A 1 557 ? 52.343 145.254 -75.837 1.00 22.44 ? 613 GLU B CB 1 ATOM 4189 C CG . GLU A 1 557 ? 52.327 146.211 -77.016 1.00 39.67 ? 613 GLU B CG 1 ATOM 4190 C CD . GLU A 1 557 ? 53.701 146.374 -77.659 1.00 40.32 ? 613 GLU B CD 1 ATOM 4191 O OE1 . GLU A 1 557 ? 54.720 146.150 -76.966 1.00 37.34 ? 613 GLU B OE1 1 ATOM 4192 O OE2 . GLU A 1 557 ? 53.757 146.722 -78.857 1.00 38.96 ? 613 GLU B OE2 1 ATOM 4193 N N . ILE A 1 558 ? 51.367 142.715 -74.669 1.00 24.53 ? 614 ILE B N 1 ATOM 4194 C CA . ILE A 1 558 ? 51.689 141.594 -73.803 1.00 25.85 ? 614 ILE B CA 1 ATOM 4195 C C . ILE A 1 558 ? 53.081 141.868 -73.255 1.00 38.62 ? 614 ILE B C 1 ATOM 4196 O O . ILE A 1 558 ? 54.045 141.914 -74.014 1.00 45.00 ? 614 ILE B O 1 ATOM 4197 C CB . ILE A 1 558 ? 51.693 140.257 -74.571 1.00 20.09 ? 614 ILE B CB 1 ATOM 4198 C CG1 . ILE A 1 558 ? 50.373 140.052 -75.308 1.00 31.03 ? 614 ILE B CG1 1 ATOM 4199 C CG2 . ILE A 1 558 ? 51.887 139.099 -73.630 1.00 19.79 ? 614 ILE B CG2 1 ATOM 4200 C CD1 . ILE A 1 558 ? 50.234 138.672 -75.920 1.00 31.51 ? 614 ILE B CD1 1 ATOM 4201 N N . PRO A 1 559 ? 53.190 142.065 -71.934 1.00 41.77 ? 615 PRO B N 1 ATOM 4202 C CA . PRO A 1 559 ? 54.458 142.462 -71.314 1.00 37.52 ? 615 PRO B CA 1 ATOM 4203 C C . PRO A 1 559 ? 55.540 141.419 -71.578 1.00 32.37 ? 615 PRO B C 1 ATOM 4204 O O . PRO A 1 559 ? 55.248 140.214 -71.584 1.00 27.53 ? 615 PRO B O 1 ATOM 4205 C CB . PRO A 1 559 ? 54.108 142.537 -69.825 1.00 47.13 ? 615 PRO B CB 1 ATOM 4206 C CG . PRO A 1 559 ? 52.933 141.628 -69.663 1.00 41.58 ? 615 PRO B CG 1 ATOM 4207 C CD . PRO A 1 559 ? 52.156 141.741 -70.935 1.00 39.51 ? 615 PRO B CD 1 ATOM 4208 N N . SER A 1 560 ? 56.765 141.881 -71.814 1.00 34.15 ? 616 SER B N 1 ATOM 4209 C CA . SER A 1 560 ? 57.841 141.001 -72.267 1.00 31.43 ? 616 SER B CA 1 ATOM 4210 C C . SER A 1 560 ? 58.097 139.873 -71.283 1.00 28.68 ? 616 SER B C 1 ATOM 4211 O O . SER A 1 560 ? 58.482 138.757 -71.669 1.00 32.28 ? 616 SER B O 1 ATOM 4212 C CB . SER A 1 560 ? 59.120 141.791 -72.552 1.00 35.25 ? 616 SER B CB 1 ATOM 4213 O OG . SER A 1 560 ? 59.489 142.584 -71.440 1.00 42.26 ? 616 SER B OG 1 ATOM 4214 N N . ARG A 1 561 ? 57.830 140.139 -70.011 1.00 30.16 ? 617 ARG B N 1 ATOM 4215 C CA . ARG A 1 561 ? 58.108 139.133 -69.006 1.00 41.15 ? 617 ARG B CA 1 ATOM 4216 C C . ARG A 1 561 ? 57.305 137.848 -69.183 1.00 43.86 ? 617 ARG B C 1 ATOM 4217 O O . ARG A 1 561 ? 57.680 136.809 -68.639 1.00 48.53 ? 617 ARG B O 1 ATOM 4218 C CB . ARG A 1 561 ? 57.908 139.666 -67.597 1.00 52.61 ? 617 ARG B CB 1 ATOM 4219 C CG . ARG A 1 561 ? 58.848 138.988 -66.617 1.00 72.19 ? 617 ARG B CG 1 ATOM 4220 C CD . ARG A 1 561 ? 58.296 138.895 -65.224 1.00 92.91 ? 617 ARG B CD 1 ATOM 4221 N NE . ARG A 1 561 ? 59.158 138.113 -64.371 1.00 108.05 ? 617 ARG B NE 1 ATOM 4222 C CZ . ARG A 1 561 ? 59.159 136.797 -64.397 1.00 118.17 ? 617 ARG B CZ 1 ATOM 4223 N NH1 . ARG A 1 561 ? 58.282 136.213 -65.175 1.00 120.64 ? 617 ARG B NH1 1 ATOM 4224 N NH2 . ARG A 1 561 ? 60.001 136.080 -63.656 1.00 122.74 ? 617 ARG B NH2 1 ATOM 4225 N N . PHE A 1 562 ? 56.234 137.889 -69.975 1.00 38.18 ? 618 PHE B N 1 ATOM 4226 C CA . PHE A 1 562 ? 55.445 136.677 -70.196 1.00 35.09 ? 618 PHE B CA 1 ATOM 4227 C C . PHE A 1 562 ? 56.265 135.589 -70.860 1.00 39.00 ? 618 PHE B C 1 ATOM 4228 O O . PHE A 1 562 ? 55.837 134.431 -70.902 1.00 44.49 ? 618 PHE B O 1 ATOM 4229 C CB . PHE A 1 562 ? 54.175 136.928 -71.013 1.00 32.56 ? 618 PHE B CB 1 ATOM 4230 C CG . PHE A 1 562 ? 53.001 137.397 -70.197 1.00 34.44 ? 618 PHE B CG 1 ATOM 4231 C CD1 . PHE A 1 562 ? 53.193 138.068 -68.990 1.00 42.47 ? 618 PHE B CD1 1 ATOM 4232 C CD2 . PHE A 1 562 ? 51.702 137.167 -70.635 1.00 26.95 ? 618 PHE B CD2 1 ATOM 4233 C CE1 . PHE A 1 562 ? 52.119 138.514 -68.242 1.00 19.62 ? 618 PHE B CE1 1 ATOM 4234 C CE2 . PHE A 1 562 ? 50.617 137.615 -69.899 1.00 19.82 ? 618 PHE B CE2 1 ATOM 4235 C CZ . PHE A 1 562 ? 50.830 138.291 -68.693 1.00 21.19 ? 618 PHE B CZ 1 ATOM 4236 N N . SER A 1 563 ? 57.442 135.949 -71.375 1.00 40.11 ? 619 SER B N 1 ATOM 4237 C CA . SER A 1 563 ? 58.336 134.921 -71.902 1.00 40.63 ? 619 SER B CA 1 ATOM 4238 C C . SER A 1 563 ? 58.840 134.007 -70.789 1.00 48.04 ? 619 SER B C 1 ATOM 4239 O O . SER A 1 563 ? 59.278 132.886 -71.057 1.00 52.79 ? 619 SER B O 1 ATOM 4240 C CB . SER A 1 563 ? 59.509 135.525 -72.675 1.00 33.86 ? 619 SER B CB 1 ATOM 4241 O OG . SER A 1 563 ? 60.103 136.587 -71.957 1.00 34.44 ? 619 SER B OG 1 ATOM 4242 N N . ASP A 1 564 ? 58.762 134.475 -69.543 1.00 44.32 ? 620 ASP B N 1 ATOM 4243 C CA . ASP A 1 564 ? 59.234 133.669 -68.422 1.00 46.12 ? 620 ASP B CA 1 ATOM 4244 C C . ASP A 1 564 ? 58.278 132.569 -67.975 1.00 46.36 ? 620 ASP B C 1 ATOM 4245 O O . ASP A 1 564 ? 58.701 131.668 -67.256 1.00 47.55 ? 620 ASP B O 1 ATOM 4246 C CB . ASP A 1 564 ? 59.533 134.518 -67.192 1.00 44.46 ? 620 ASP B CB 1 ATOM 4247 C CG . ASP A 1 564 ? 60.817 135.315 -67.301 1.00 46.96 ? 620 ASP B CG 1 ATOM 4248 O OD1 . ASP A 1 564 ? 61.678 135.020 -68.164 1.00 45.10 ? 620 ASP B OD1 1 ATOM 4249 O OD2 . ASP A 1 564 ? 60.966 136.247 -66.485 1.00 45.56 ? 620 ASP B OD2 1 ATOM 4250 N N . LEU A 1 565 ? 57.011 132.592 -68.381 1.00 38.82 ? 621 LEU B N 1 ATOM 4251 C CA . LEU A 1 565 ? 56.149 131.592 -67.782 1.00 38.66 ? 621 LEU B CA 1 ATOM 4252 C C . LEU A 1 565 ? 56.280 130.365 -68.640 1.00 40.56 ? 621 LEU B C 1 ATOM 4253 O O . LEU A 1 565 ? 55.476 130.125 -69.540 1.00 38.59 ? 621 LEU B O 1 ATOM 4254 C CB . LEU A 1 565 ? 54.699 132.060 -67.840 1.00 31.82 ? 621 LEU B CB 1 ATOM 4255 C CG . LEU A 1 565 ? 54.468 133.392 -67.142 1.00 29.54 ? 621 LEU B CG 1 ATOM 4256 C CD1 . LEU A 1 565 ? 53.214 134.056 -67.676 1.00 21.60 ? 621 LEU B CD1 1 ATOM 4257 C CD2 . LEU A 1 565 ? 54.387 133.158 -65.635 1.00 31.07 ? 621 LEU B CD2 1 ATOM 4258 N N . LYS A 1 566 ? 57.199 129.506 -68.219 1.00 38.44 ? 622 LYS B N 1 ATOM 4259 C CA . LYS A 1 566 ? 57.681 128.419 -69.049 1.00 40.02 ? 622 LYS B CA 1 ATOM 4260 C C . LYS A 1 566 ? 56.824 127.201 -68.759 1.00 40.81 ? 622 LYS B C 1 ATOM 4261 O O . LYS A 1 566 ? 56.849 126.212 -69.493 1.00 43.19 ? 622 LYS B O 1 ATOM 4262 C CB . LYS A 1 566 ? 59.158 128.145 -68.724 1.00 43.76 ? 622 LYS B CB 1 ATOM 4263 C CG . LYS A 1 566 ? 60.084 128.048 -69.928 1.00 51.08 ? 622 LYS B CG 1 ATOM 4264 C CD . LYS A 1 566 ? 60.316 129.405 -70.581 1.00 55.09 ? 622 LYS B CD 1 ATOM 4265 C CE . LYS A 1 566 ? 61.000 129.254 -71.935 1.00 57.41 ? 622 LYS B CE 1 ATOM 4266 N NZ . LYS A 1 566 ? 60.714 130.406 -72.848 1.00 60.22 ? 622 LYS B NZ 1 ATOM 4267 N N . ASN A 1 567 ? 56.063 127.283 -67.672 1.00 37.49 ? 623 ASN B N 1 ATOM 4268 C CA . ASN A 1 567 ? 55.158 126.204 -67.297 1.00 43.09 ? 623 ASN B CA 1 ATOM 4269 C C . ASN A 1 567 ? 53.679 126.386 -67.692 1.00 38.77 ? 623 ASN B C 1 ATOM 4270 O O . ASN A 1 567 ? 52.875 125.474 -67.493 1.00 42.58 ? 623 ASN B O 1 ATOM 4271 C CB . ASN A 1 567 ? 55.270 125.916 -65.791 1.00 45.79 ? 623 ASN B CB 1 ATOM 4272 C CG . ASN A 1 567 ? 56.587 125.250 -65.412 1.00 45.21 ? 623 ASN B CG 1 ATOM 4273 O OD1 . ASN A 1 567 ? 57.111 124.407 -66.144 1.00 45.81 ? 623 ASN B OD1 1 ATOM 4274 N ND2 . ASN A 1 567 ? 57.121 125.624 -64.257 1.00 43.60 ? 623 ASN B ND2 1 ATOM 4275 N N . LEU A 1 568 ? 53.319 127.536 -68.256 1.00 32.71 ? 624 LEU B N 1 ATOM 4276 C CA . LEU A 1 568 ? 51.911 127.824 -68.516 1.00 28.65 ? 624 LEU B CA 1 ATOM 4277 C C . LEU A 1 568 ? 51.358 126.973 -69.648 1.00 26.04 ? 624 LEU B C 1 ATOM 4278 O O . LEU A 1 568 ? 51.852 127.026 -70.763 1.00 36.33 ? 624 LEU B O 1 ATOM 4279 C CB . LEU A 1 568 ? 51.723 129.299 -68.841 1.00 16.67 ? 624 LEU B CB 1 ATOM 4280 C CG . LEU A 1 568 ? 50.279 129.777 -68.988 1.00 29.05 ? 624 LEU B CG 1 ATOM 4281 C CD1 . LEU A 1 568 ? 49.444 129.455 -67.732 1.00 20.68 ? 624 LEU B CD1 1 ATOM 4282 C CD2 . LEU A 1 568 ? 50.265 131.268 -69.273 1.00 27.47 ? 624 LEU B CD2 1 ATOM 4283 N N . GLY A 1 569 ? 50.329 126.188 -69.358 1.00 24.40 ? 625 GLY B N 1 ATOM 4284 C CA . GLY A 1 569 ? 49.720 125.340 -70.366 1.00 24.77 ? 625 GLY B CA 1 ATOM 4285 C C . GLY A 1 569 ? 48.578 125.981 -71.138 1.00 28.35 ? 625 GLY B C 1 ATOM 4286 O O . GLY A 1 569 ? 48.333 125.647 -72.296 1.00 36.45 ? 625 GLY B O 1 ATOM 4287 N N . VAL A 1 570 ? 47.873 126.908 -70.499 1.00 24.71 ? 626 VAL B N 1 ATOM 4288 C CA . VAL A 1 570 ? 46.688 127.516 -71.100 1.00 24.51 ? 626 VAL B CA 1 ATOM 4289 C C . VAL A 1 570 ? 46.676 129.023 -70.855 1.00 22.71 ? 626 VAL B C 1 ATOM 4290 O O . VAL A 1 570 ? 46.903 129.485 -69.733 1.00 20.51 ? 626 VAL B O 1 ATOM 4291 C CB . VAL A 1 570 ? 45.399 126.860 -70.562 1.00 23.83 ? 626 VAL B CB 1 ATOM 4292 C CG1 . VAL A 1 570 ? 44.159 127.611 -71.039 1.00 14.14 ? 626 VAL B CG1 1 ATOM 4293 C CG2 . VAL A 1 570 ? 45.335 125.392 -70.979 1.00 24.34 ? 626 VAL B CG2 1 ATOM 4294 N N . LEU A 1 571 ? 46.448 129.788 -71.917 1.00 23.28 ? 627 LEU B N 1 ATOM 4295 C CA . LEU A 1 571 ? 46.436 131.246 -71.826 1.00 13.74 ? 627 LEU B CA 1 ATOM 4296 C C . LEU A 1 571 ? 45.282 131.859 -72.618 1.00 17.89 ? 627 LEU B C 1 ATOM 4297 O O . LEU A 1 571 ? 45.211 131.703 -73.839 1.00 28.06 ? 627 LEU B O 1 ATOM 4298 C CB . LEU A 1 571 ? 47.759 131.802 -72.354 1.00 14.77 ? 627 LEU B CB 1 ATOM 4299 C CG . LEU A 1 571 ? 47.892 133.320 -72.338 1.00 21.83 ? 627 LEU B CG 1 ATOM 4300 C CD1 . LEU A 1 571 ? 47.753 133.905 -70.909 1.00 15.28 ? 627 LEU B CD1 1 ATOM 4301 C CD2 . LEU A 1 571 ? 49.218 133.684 -72.934 1.00 21.00 ? 627 LEU B CD2 1 ATOM 4302 N N . ASP A 1 572 ? 44.377 132.550 -71.927 1.00 21.90 ? 628 ASP B N 1 ATOM 4303 C CA . ASP A 1 572 ? 43.285 133.262 -72.593 1.00 20.48 ? 628 ASP B CA 1 ATOM 4304 C C . ASP A 1 572 ? 43.300 134.753 -72.264 1.00 25.07 ? 628 ASP B C 1 ATOM 4305 O O . ASP A 1 572 ? 42.958 135.149 -71.145 1.00 29.86 ? 628 ASP B O 1 ATOM 4306 C CB . ASP A 1 572 ? 41.944 132.659 -72.173 1.00 18.68 ? 628 ASP B CB 1 ATOM 4307 C CG . ASP A 1 572 ? 40.799 133.065 -73.090 1.00 25.50 ? 628 ASP B CG 1 ATOM 4308 O OD1 . ASP A 1 572 ? 40.950 134.053 -73.838 1.00 28.30 ? 628 ASP B OD1 1 ATOM 4309 O OD2 . ASP A 1 572 ? 39.738 132.395 -73.055 1.00 24.37 ? 628 ASP B OD2 1 ATOM 4310 N N . VAL A 1 573 ? 43.704 135.561 -73.245 1.00 17.45 ? 629 VAL B N 1 ATOM 4311 C CA . VAL A 1 573 ? 43.614 137.024 -73.208 1.00 13.86 ? 629 VAL B CA 1 ATOM 4312 C C . VAL A 1 573 ? 42.481 137.600 -74.045 1.00 13.46 ? 629 VAL B C 1 ATOM 4313 O O . VAL A 1 573 ? 42.370 138.809 -74.186 1.00 19.68 ? 629 VAL B O 1 ATOM 4314 C CB . VAL A 1 573 ? 44.950 137.696 -73.621 1.00 14.89 ? 629 VAL B CB 1 ATOM 4315 C CG1 . VAL A 1 573 ? 46.056 137.277 -72.666 1.00 15.36 ? 629 VAL B CG1 1 ATOM 4316 C CG2 . VAL A 1 573 ? 45.321 137.328 -75.061 1.00 15.07 ? 629 VAL B CG2 1 ATOM 4317 N N . SER A 1 574 ? 41.652 136.739 -74.611 1.00 12.75 ? 630 SER B N 1 ATOM 4318 C CA . SER A 1 574 ? 40.696 137.129 -75.653 1.00 12.44 ? 630 SER B CA 1 ATOM 4319 C C . SER A 1 574 ? 39.704 138.188 -75.209 1.00 12.25 ? 630 SER B C 1 ATOM 4320 O O . SER A 1 574 ? 39.486 138.376 -74.024 1.00 14.13 ? 630 SER B O 1 ATOM 4321 C CB . SER A 1 574 ? 39.892 135.912 -76.088 1.00 24.35 ? 630 SER B CB 1 ATOM 4322 O OG . SER A 1 574 ? 39.039 135.498 -75.028 1.00 20.11 ? 630 SER B OG 1 ATOM 4323 N N . HIS A 1 575 ? 39.112 138.891 -76.170 1.00 20.53 ? 631 HIS B N 1 ATOM 4324 C CA . HIS A 1 575 ? 38.147 139.951 -75.870 1.00 15.75 ? 631 HIS B CA 1 ATOM 4325 C C . HIS A 1 575 ? 38.710 141.014 -74.975 1.00 13.94 ? 631 HIS B C 1 ATOM 4326 O O . HIS A 1 575 ? 38.128 141.331 -73.938 1.00 18.30 ? 631 HIS B O 1 ATOM 4327 C CB . HIS A 1 575 ? 36.874 139.413 -75.214 1.00 12.19 ? 631 HIS B CB 1 ATOM 4328 C CG . HIS A 1 575 ? 35.972 138.711 -76.168 1.00 10.68 ? 631 HIS B CG 1 ATOM 4329 N ND1 . HIS A 1 575 ? 35.968 137.339 -76.309 1.00 19.24 ? 631 HIS B ND1 1 ATOM 4330 C CD2 . HIS A 1 575 ? 35.073 139.191 -77.055 1.00 12.65 ? 631 HIS B CD2 1 ATOM 4331 C CE1 . HIS A 1 575 ? 35.087 137.002 -77.234 1.00 22.83 ? 631 HIS B CE1 1 ATOM 4332 N NE2 . HIS A 1 575 ? 34.532 138.107 -77.704 1.00 20.98 ? 631 HIS B NE2 1 ATOM 4333 N N . ASN A 1 576 ? 39.848 141.550 -75.374 1.00 15.92 ? 632 ASN B N 1 ATOM 4334 C CA . ASN A 1 576 ? 40.372 142.758 -74.766 1.00 18.39 ? 632 ASN B CA 1 ATOM 4335 C C . ASN A 1 576 ? 40.756 143.746 -75.866 1.00 19.13 ? 632 ASN B C 1 ATOM 4336 O O . ASN A 1 576 ? 40.407 143.556 -77.028 1.00 19.00 ? 632 ASN B O 1 ATOM 4337 C CB . ASN A 1 576 ? 41.564 142.445 -73.861 1.00 20.52 ? 632 ASN B CB 1 ATOM 4338 C CG . ASN A 1 576 ? 41.148 141.789 -72.576 1.00 24.62 ? 632 ASN B CG 1 ATOM 4339 O OD1 . ASN A 1 576 ? 40.638 142.450 -71.675 1.00 24.31 ? 632 ASN B OD1 1 ATOM 4340 N ND2 . ASN A 1 576 ? 41.364 140.483 -72.474 1.00 26.58 ? 632 ASN B ND2 1 ATOM 4341 N N . GLN A 1 577 ? 41.389 144.840 -75.461 1.00 17.92 ? 633 GLN B N 1 ATOM 4342 C CA . GLN A 1 577 ? 41.936 145.854 -76.352 1.00 16.42 ? 633 GLN B CA 1 ATOM 4343 C C . GLN A 1 577 ? 43.437 145.788 -76.579 1.00 17.21 ? 633 GLN B C 1 ATOM 4344 O O . GLN A 1 577 ? 44.057 146.803 -76.894 1.00 26.94 ? 633 GLN B O 1 ATOM 4345 C CB . GLN A 1 577 ? 41.428 147.240 -76.004 1.00 30.07 ? 633 GLN B CB 1 ATOM 4346 C CG . GLN A 1 577 ? 39.939 147.359 -76.257 1.00 26.02 ? 633 GLN B CG 1 ATOM 4347 C CD . GLN A 1 577 ? 39.293 148.409 -75.386 1.00 41.57 ? 633 GLN B CD 1 ATOM 4348 O OE1 . GLN A 1 577 ? 38.846 148.125 -74.268 1.00 44.68 ? 633 GLN B OE1 1 ATOM 4349 N NE2 . GLN A 1 577 ? 39.245 149.637 -75.888 1.00 49.32 ? 633 GLN B NE2 1 ATOM 4350 N N . LEU A 1 578 ? 44.031 144.642 -76.260 1.00 19.01 ? 634 LEU B N 1 ATOM 4351 C CA . LEU A 1 578 ? 45.471 144.395 -76.427 1.00 17.79 ? 634 LEU B CA 1 ATOM 4352 C C . LEU A 1 578 ? 46.078 144.675 -77.829 1.00 26.90 ? 634 LEU B C 1 ATOM 4353 O O . LEU A 1 578 ? 45.470 144.368 -78.852 1.00 17.95 ? 634 LEU B O 1 ATOM 4354 C CB . LEU A 1 578 ? 45.767 142.959 -75.991 1.00 17.39 ? 634 LEU B CB 1 ATOM 4355 C CG . LEU A 1 578 ? 45.399 142.743 -74.515 1.00 24.61 ? 634 LEU B CG 1 ATOM 4356 C CD1 . LEU A 1 578 ? 45.413 141.273 -74.087 1.00 18.65 ? 634 LEU B CD1 1 ATOM 4357 C CD2 . LEU A 1 578 ? 46.321 143.576 -73.614 1.00 24.79 ? 634 LEU B CD2 1 ATOM 4358 N N . THR A 1 579 ? 47.282 145.253 -77.864 1.00 27.98 ? 635 THR B N 1 ATOM 4359 C CA . THR A 1 579 ? 47.960 145.580 -79.137 1.00 27.19 ? 635 THR B CA 1 ATOM 4360 C C . THR A 1 579 ? 49.368 144.988 -79.358 1.00 26.79 ? 635 THR B C 1 ATOM 4361 O O . THR A 1 579 ? 49.926 144.279 -78.504 1.00 20.63 ? 635 THR B O 1 ATOM 4362 C CB . THR A 1 579 ? 48.064 147.118 -79.380 1.00 20.63 ? 635 THR B CB 1 ATOM 4363 O OG1 . THR A 1 579 ? 48.823 147.739 -78.331 1.00 23.98 ? 635 THR B OG1 1 ATOM 4364 C CG2 . THR A 1 579 ? 46.681 147.762 -79.470 1.00 20.07 ? 635 THR B CG2 1 ATOM 4365 N N . GLY A 1 580 ? 49.934 145.301 -80.524 1.00 21.20 ? 636 GLY B N 1 ATOM 4366 C CA . GLY A 1 580 ? 51.254 144.821 -80.889 1.00 21.92 ? 636 GLY B CA 1 ATOM 4367 C C . GLY A 1 580 ? 51.235 143.361 -81.287 1.00 21.42 ? 636 GLY B C 1 ATOM 4368 O O . GLY A 1 580 ? 50.181 142.815 -81.597 1.00 33.76 ? 636 GLY B O 1 ATOM 4369 N N . ASN A 1 581 ? 52.397 142.718 -81.269 1.00 21.98 ? 637 ASN B N 1 ATOM 4370 C CA . ASN A 1 581 ? 52.488 141.346 -81.738 1.00 25.20 ? 637 ASN B CA 1 ATOM 4371 C C . ASN A 1 581 ? 52.617 140.293 -80.657 1.00 28.85 ? 637 ASN B C 1 ATOM 4372 O O . ASN A 1 581 ? 52.518 140.576 -79.463 1.00 31.20 ? 637 ASN B O 1 ATOM 4373 C CB . ASN A 1 581 ? 53.606 141.180 -82.769 1.00 26.53 ? 637 ASN B CB 1 ATOM 4374 C CG . ASN A 1 581 ? 54.966 141.517 -82.212 1.00 32.81 ? 637 ASN B CG 1 ATOM 4375 O OD1 . ASN A 1 581 ? 55.433 140.893 -81.264 1.00 36.09 ? 637 ASN B OD1 1 ATOM 4376 N ND2 . ASN A 1 581 ? 55.622 142.497 -82.814 1.00 35.81 ? 637 ASN B ND2 1 ATOM 4377 N N . LEU A 1 582 ? 52.792 139.062 -81.112 1.00 28.89 ? 638 LEU B N 1 ATOM 4378 C CA . LEU A 1 582 ? 52.855 137.894 -80.246 1.00 24.61 ? 638 LEU B CA 1 ATOM 4379 C C . LEU A 1 582 ? 54.257 137.377 -79.968 1.00 21.44 ? 638 LEU B C 1 ATOM 4380 O O . LEU A 1 582 ? 54.402 136.325 -79.359 1.00 36.16 ? 638 LEU B O 1 ATOM 4381 C CB . LEU A 1 582 ? 51.980 136.780 -80.831 1.00 19.76 ? 638 LEU B CB 1 ATOM 4382 C CG . LEU A 1 582 ? 50.516 137.208 -80.986 1.00 23.63 ? 638 LEU B CG 1 ATOM 4383 C CD1 . LEU A 1 582 ? 49.633 136.028 -81.341 1.00 21.41 ? 638 LEU B CD1 1 ATOM 4384 C CD2 . LEU A 1 582 ? 50.004 137.882 -79.691 1.00 28.46 ? 638 LEU B CD2 1 ATOM 4385 N N . ASN A 1 583 ? 55.278 138.075 -80.461 1.00 36.37 ? 639 ASN B N 1 ATOM 4386 C CA . ASN A 1 583 ? 56.660 137.559 -80.437 1.00 32.04 ? 639 ASN B CA 1 ATOM 4387 C C . ASN A 1 583 ? 57.134 137.058 -79.080 1.00 33.43 ? 639 ASN B C 1 ATOM 4388 O O . ASN A 1 583 ? 57.886 136.082 -78.994 1.00 34.92 ? 639 ASN B O 1 ATOM 4389 C CB . ASN A 1 583 ? 57.643 138.599 -80.979 1.00 26.32 ? 639 ASN B CB 1 ATOM 4390 C CG . ASN A 1 583 ? 57.373 138.939 -82.429 1.00 26.83 ? 639 ASN B CG 1 ATOM 4391 O OD1 . ASN A 1 583 ? 56.660 138.212 -83.126 1.00 30.56 ? 639 ASN B OD1 1 ATOM 4392 N ND2 . ASN A 1 583 ? 57.930 140.046 -82.889 1.00 25.34 ? 639 ASN B ND2 1 ATOM 4393 N N . VAL A 1 584 ? 56.664 137.724 -78.030 1.00 31.03 ? 640 VAL B N 1 ATOM 4394 C CA . VAL A 1 584 ? 57.023 137.409 -76.664 1.00 36.15 ? 640 VAL B CA 1 ATOM 4395 C C . VAL A 1 584 ? 56.625 135.973 -76.309 1.00 41.91 ? 640 VAL B C 1 ATOM 4396 O O . VAL A 1 584 ? 57.202 135.358 -75.404 1.00 41.35 ? 640 VAL B O 1 ATOM 4397 C CB . VAL A 1 584 ? 56.343 138.406 -75.712 1.00 43.74 ? 640 VAL B CB 1 ATOM 4398 C CG1 . VAL A 1 584 ? 54.829 138.355 -75.886 1.00 41.75 ? 640 VAL B CG1 1 ATOM 4399 C CG2 . VAL A 1 584 ? 56.735 138.145 -74.268 1.00 49.34 ? 640 VAL B CG2 1 ATOM 4400 N N . LEU A 1 585 ? 55.644 135.440 -77.036 1.00 38.94 ? 641 LEU B N 1 ATOM 4401 C CA . LEU A 1 585 ? 55.116 134.103 -76.772 1.00 32.68 ? 641 LEU B CA 1 ATOM 4402 C C . LEU A 1 585 ? 55.739 132.968 -77.587 1.00 36.85 ? 641 LEU B C 1 ATOM 4403 O O . LEU A 1 585 ? 55.479 131.797 -77.296 1.00 37.87 ? 641 LEU B O 1 ATOM 4404 C CB . LEU A 1 585 ? 53.599 134.090 -76.978 1.00 28.46 ? 641 LEU B CB 1 ATOM 4405 C CG . LEU A 1 585 ? 52.662 134.468 -75.827 1.00 28.93 ? 641 LEU B CG 1 ATOM 4406 C CD1 . LEU A 1 585 ? 53.327 135.346 -74.773 1.00 29.43 ? 641 LEU B CD1 1 ATOM 4407 C CD2 . LEU A 1 585 ? 51.418 135.153 -76.364 1.00 29.60 ? 641 LEU B CD2 1 ATOM 4408 N N . THR A 1 586 ? 56.554 133.298 -78.593 1.00 43.57 ? 642 THR B N 1 ATOM 4409 C CA . THR A 1 586 ? 57.014 132.290 -79.567 1.00 44.34 ? 642 THR B CA 1 ATOM 4410 C C . THR A 1 586 ? 57.824 131.177 -78.911 1.00 41.38 ? 642 THR B C 1 ATOM 4411 O O . THR A 1 586 ? 57.935 130.074 -79.457 1.00 37.98 ? 642 THR B O 1 ATOM 4412 C CB . THR A 1 586 ? 57.832 132.899 -80.769 1.00 44.78 ? 642 THR B CB 1 ATOM 4413 O OG1 . THR A 1 586 ? 58.958 133.637 -80.288 1.00 43.58 ? 642 THR B OG1 1 ATOM 4414 C CG2 . THR A 1 586 ? 56.967 133.819 -81.628 1.00 44.41 ? 642 THR B CG2 1 ATOM 4415 N N . ASP A 1 587 ? 58.372 131.485 -77.736 1.00 41.06 ? 643 ASP B N 1 ATOM 4416 C CA . ASP A 1 587 ? 59.285 130.601 -77.013 1.00 50.12 ? 643 ASP B CA 1 ATOM 4417 C C . ASP A 1 587 ? 58.671 129.746 -75.899 1.00 48.05 ? 643 ASP B C 1 ATOM 4418 O O . ASP A 1 587 ? 59.401 129.061 -75.180 1.00 44.60 ? 643 ASP B O 1 ATOM 4419 C CB . ASP A 1 587 ? 60.467 131.400 -76.456 1.00 61.37 ? 643 ASP B CB 1 ATOM 4420 C CG . ASP A 1 587 ? 61.806 130.861 -76.922 1.00 67.82 ? 643 ASP B CG 1 ATOM 4421 O OD1 . ASP A 1 587 ? 61.885 130.397 -78.082 1.00 71.41 ? 643 ASP B OD1 1 ATOM 4422 O OD2 . ASP A 1 587 ? 62.773 130.904 -76.126 1.00 67.59 ? 643 ASP B OD2 1 ATOM 4423 N N . LEU A 1 588 ? 57.354 129.781 -75.726 1.00 47.01 ? 644 LEU B N 1 ATOM 4424 C CA . LEU A 1 588 ? 56.781 128.925 -74.699 1.00 40.54 ? 644 LEU B CA 1 ATOM 4425 C C . LEU A 1 588 ? 56.428 127.610 -75.369 1.00 45.22 ? 644 LEU B C 1 ATOM 4426 O O . LEU A 1 588 ? 55.419 127.495 -76.069 1.00 48.67 ? 644 LEU B O 1 ATOM 4427 C CB . LEU A 1 588 ? 55.531 129.560 -74.085 1.00 25.64 ? 644 LEU B CB 1 ATOM 4428 C CG . LEU A 1 588 ? 55.719 130.961 -73.499 1.00 28.56 ? 644 LEU B CG 1 ATOM 4429 C CD1 . LEU A 1 588 ? 54.378 131.587 -73.085 1.00 26.15 ? 644 LEU B CD1 1 ATOM 4430 C CD2 . LEU A 1 588 ? 56.691 130.935 -72.319 1.00 28.44 ? 644 LEU B CD2 1 ATOM 4431 N N . GLN A 1 589 ? 57.248 126.603 -75.090 1.00 44.74 ? 645 GLN B N 1 ATOM 4432 C CA . GLN A 1 589 ? 57.118 125.294 -75.713 1.00 49.85 ? 645 GLN B CA 1 ATOM 4433 C C . GLN A 1 589 ? 56.043 124.475 -75.003 1.00 50.67 ? 645 GLN B C 1 ATOM 4434 O O . GLN A 1 589 ? 55.520 123.501 -75.551 1.00 53.11 ? 645 GLN B O 1 ATOM 4435 C CB . GLN A 1 589 ? 58.466 124.560 -75.696 1.00 57.78 ? 645 GLN B CB 1 ATOM 4436 C CG . GLN A 1 589 ? 58.907 124.029 -74.319 1.00 69.62 ? 645 GLN B CG 1 ATOM 4437 C CD . GLN A 1 589 ? 59.398 125.112 -73.352 1.00 75.79 ? 645 GLN B CD 1 ATOM 4438 O OE1 . GLN A 1 589 ? 59.356 126.307 -73.652 1.00 82.63 ? 645 GLN B OE1 1 ATOM 4439 N NE2 . GLN A 1 589 ? 59.868 124.686 -72.182 1.00 72.27 ? 645 GLN B NE2 1 ATOM 4440 N N . ASN A 1 590 ? 55.714 124.883 -73.780 1.00 48.36 ? 646 ASN B N 1 ATOM 4441 C CA . ASN A 1 590 ? 54.669 124.222 -73.008 1.00 48.12 ? 646 ASN B CA 1 ATOM 4442 C C . ASN A 1 590 ? 53.296 124.872 -73.165 1.00 41.75 ? 646 ASN B C 1 ATOM 4443 O O . ASN A 1 590 ? 52.317 124.421 -72.581 1.00 33.09 ? 646 ASN B O 1 ATOM 4444 C CB . ASN A 1 590 ? 55.061 124.143 -71.537 1.00 55.29 ? 646 ASN B CB 1 ATOM 4445 C CG . ASN A 1 590 ? 56.153 123.128 -71.287 1.00 60.95 ? 646 ASN B CG 1 ATOM 4446 O OD1 . ASN A 1 590 ? 56.188 122.074 -71.924 1.00 64.39 ? 646 ASN B OD1 1 ATOM 4447 N ND2 . ASN A 1 590 ? 57.056 123.439 -70.360 1.00 59.33 ? 646 ASN B ND2 1 ATOM 4448 N N . LEU A 1 591 ? 53.217 125.927 -73.964 1.00 42.00 ? 647 LEU B N 1 ATOM 4449 C CA . LEU A 1 591 ? 51.923 126.513 -74.250 1.00 39.40 ? 647 LEU B CA 1 ATOM 4450 C C . LEU A 1 591 ? 51.114 125.561 -75.127 1.00 43.11 ? 647 LEU B C 1 ATOM 4451 O O . LEU A 1 591 ? 51.592 125.081 -76.156 1.00 52.83 ? 647 LEU B O 1 ATOM 4452 C CB . LEU A 1 591 ? 52.080 127.871 -74.918 1.00 40.57 ? 647 LEU B CB 1 ATOM 4453 C CG . LEU A 1 591 ? 50.828 128.743 -74.892 1.00 34.20 ? 647 LEU B CG 1 ATOM 4454 C CD1 . LEU A 1 591 ? 50.219 128.756 -73.494 1.00 32.80 ? 647 LEU B CD1 1 ATOM 4455 C CD2 . LEU A 1 591 ? 51.192 130.141 -75.327 1.00 32.14 ? 647 LEU B CD2 1 ATOM 4456 N N . VAL A 1 592 ? 49.887 125.293 -74.699 1.00 35.99 ? 648 VAL B N 1 ATOM 4457 C CA . VAL A 1 592 ? 49.011 124.320 -75.335 1.00 32.67 ? 648 VAL B CA 1 ATOM 4458 C C . VAL A 1 592 ? 47.799 125.020 -75.942 1.00 32.20 ? 648 VAL B C 1 ATOM 4459 O O . VAL A 1 592 ? 47.514 124.878 -77.126 1.00 33.77 ? 648 VAL B O 1 ATOM 4460 C CB . VAL A 1 592 ? 48.557 123.237 -74.339 1.00 37.55 ? 648 VAL B CB 1 ATOM 4461 C CG1 . VAL A 1 592 ? 47.653 122.221 -75.023 1.00 36.26 ? 648 VAL B CG1 1 ATOM 4462 C CG2 . VAL A 1 592 ? 49.773 122.554 -73.715 1.00 37.78 ? 648 VAL B CG2 1 ATOM 4463 N N . SER A 1 593 ? 47.051 125.725 -75.106 1.00 32.06 ? 649 SER B N 1 ATOM 4464 C CA . SER A 1 593 ? 45.883 126.468 -75.565 1.00 25.91 ? 649 SER B CA 1 ATOM 4465 C C . SER A 1 593 ? 46.162 127.977 -75.526 1.00 19.81 ? 649 SER B C 1 ATOM 4466 O O . SER A 1 593 ? 46.596 128.513 -74.508 1.00 27.85 ? 649 SER B O 1 ATOM 4467 C CB . SER A 1 593 ? 44.669 126.086 -74.702 1.00 25.72 ? 649 SER B CB 1 ATOM 4468 O OG . SER A 1 593 ? 43.530 126.878 -74.973 1.00 26.34 ? 649 SER B OG 1 ATOM 4469 N N . LEU A 1 594 ? 45.944 128.658 -76.646 1.00 21.46 ? 650 LEU B N 1 ATOM 4470 C CA . LEU A 1 594 ? 46.152 130.109 -76.725 1.00 21.07 ? 650 LEU B CA 1 ATOM 4471 C C . LEU A 1 594 ? 44.935 130.714 -77.339 1.00 13.15 ? 650 LEU B C 1 ATOM 4472 O O . LEU A 1 594 ? 44.622 130.393 -78.472 1.00 25.06 ? 650 LEU B O 1 ATOM 4473 C CB . LEU A 1 594 ? 47.353 130.467 -77.609 1.00 14.63 ? 650 LEU B CB 1 ATOM 4474 C CG . LEU A 1 594 ? 47.713 131.964 -77.702 1.00 15.23 ? 650 LEU B CG 1 ATOM 4475 C CD1 . LEU A 1 594 ? 47.858 132.588 -76.326 1.00 15.35 ? 650 LEU B CD1 1 ATOM 4476 C CD2 . LEU A 1 594 ? 48.988 132.203 -78.504 1.00 16.22 ? 650 LEU B CD2 1 ATOM 4477 N N . ASN A 1 595 ? 44.228 131.565 -76.603 1.00 12.85 ? 651 ASN B N 1 ATOM 4478 C CA . ASN A 1 595 ? 43.128 132.289 -77.216 1.00 12.46 ? 651 ASN B CA 1 ATOM 4479 C C . ASN A 1 595 ? 43.461 133.787 -77.260 1.00 24.20 ? 651 ASN B C 1 ATOM 4480 O O . ASN A 1 595 ? 43.393 134.483 -76.248 1.00 39.04 ? 651 ASN B O 1 ATOM 4481 C CB . ASN A 1 595 ? 41.821 132.003 -76.458 1.00 11.56 ? 651 ASN B CB 1 ATOM 4482 C CG . ASN A 1 595 ? 40.593 132.453 -77.219 1.00 11.09 ? 651 ASN B CG 1 ATOM 4483 O OD1 . ASN A 1 595 ? 40.708 133.338 -78.068 1.00 11.49 ? 651 ASN B OD1 1 ATOM 4484 N ND2 . ASN A 1 595 ? 39.397 131.868 -76.924 1.00 10.26 ? 651 ASN B ND2 1 ATOM 4485 N N . ILE A 1 596 ? 43.852 134.269 -78.436 1.00 20.61 ? 652 ILE B N 1 ATOM 4486 C CA . ILE A 1 596 ? 44.171 135.687 -78.639 1.00 18.34 ? 652 ILE B CA 1 ATOM 4487 C C . ILE A 1 596 ? 43.102 136.524 -79.353 1.00 13.91 ? 652 ILE B C 1 ATOM 4488 O O . ILE A 1 596 ? 43.331 137.685 -79.676 1.00 22.08 ? 652 ILE B O 1 ATOM 4489 C CB . ILE A 1 596 ? 45.590 135.914 -79.233 1.00 15.17 ? 652 ILE B CB 1 ATOM 4490 C CG1 . ILE A 1 596 ? 45.838 135.071 -80.505 1.00 15.23 ? 652 ILE B CG1 1 ATOM 4491 C CG2 . ILE A 1 596 ? 46.631 135.576 -78.183 1.00 15.59 ? 652 ILE B CG2 1 ATOM 4492 C CD1 . ILE A 1 596 ? 44.895 135.310 -81.630 1.00 14.88 ? 652 ILE B CD1 1 ATOM 4493 N N . SER A 1 597 ? 41.967 135.907 -79.638 1.00 13.11 ? 653 SER B N 1 ATOM 4494 C CA . SER A 1 597 ? 40.933 136.518 -80.464 1.00 26.51 ? 653 SER B CA 1 ATOM 4495 C C . SER A 1 597 ? 40.269 137.743 -79.827 1.00 12.80 ? 653 SER B C 1 ATOM 4496 O O . SER A 1 597 ? 40.368 137.957 -78.627 1.00 25.31 ? 653 SER B O 1 ATOM 4497 C CB . SER A 1 597 ? 39.881 135.471 -80.832 1.00 12.01 ? 653 SER B CB 1 ATOM 4498 O OG . SER A 1 597 ? 38.998 135.261 -79.758 1.00 14.09 ? 653 SER B OG 1 ATOM 4499 N N . TYR A 1 598 ? 39.611 138.548 -80.660 1.00 12.85 ? 654 TYR B N 1 ATOM 4500 C CA . TYR A 1 598 ? 38.944 139.799 -80.267 1.00 12.86 ? 654 TYR B CA 1 ATOM 4501 C C . TYR A 1 598 ? 39.836 140.772 -79.518 1.00 22.60 ? 654 TYR B C 1 ATOM 4502 O O . TYR A 1 598 ? 39.500 141.258 -78.441 1.00 29.15 ? 654 TYR B O 1 ATOM 4503 C CB . TYR A 1 598 ? 37.638 139.533 -79.520 1.00 28.16 ? 654 TYR B CB 1 ATOM 4504 C CG . TYR A 1 598 ? 36.641 138.791 -80.370 1.00 27.01 ? 654 TYR B CG 1 ATOM 4505 C CD1 . TYR A 1 598 ? 35.768 139.476 -81.206 1.00 23.40 ? 654 TYR B CD1 1 ATOM 4506 C CD2 . TYR A 1 598 ? 36.597 137.400 -80.367 1.00 26.82 ? 654 TYR B CD2 1 ATOM 4507 C CE1 . TYR A 1 598 ? 34.862 138.796 -82.001 1.00 16.64 ? 654 TYR B CE1 1 ATOM 4508 C CE2 . TYR A 1 598 ? 35.696 136.716 -81.153 1.00 20.72 ? 654 TYR B CE2 1 ATOM 4509 C CZ . TYR A 1 598 ? 34.834 137.421 -81.968 1.00 25.38 ? 654 TYR B CZ 1 ATOM 4510 O OH . TYR A 1 598 ? 33.932 136.748 -82.760 1.00 39.65 ? 654 TYR B OH 1 ATOM 4511 N N . ASN A 1 599 ? 40.985 141.043 -80.115 1.00 14.34 ? 655 ASN B N 1 ATOM 4512 C CA . ASN A 1 599 ? 41.883 142.072 -79.650 1.00 15.15 ? 655 ASN B CA 1 ATOM 4513 C C . ASN A 1 599 ? 42.279 142.958 -80.839 1.00 18.48 ? 655 ASN B C 1 ATOM 4514 O O . ASN A 1 599 ? 41.705 142.855 -81.925 1.00 16.88 ? 655 ASN B O 1 ATOM 4515 C CB . ASN A 1 599 ? 43.121 141.454 -78.982 1.00 15.54 ? 655 ASN B CB 1 ATOM 4516 C CG . ASN A 1 599 ? 42.843 140.946 -77.567 1.00 19.91 ? 655 ASN B CG 1 ATOM 4517 O OD1 . ASN A 1 599 ? 42.781 141.724 -76.617 1.00 15.26 ? 655 ASN B OD1 1 ATOM 4518 N ND2 . ASN A 1 599 ? 42.703 139.636 -77.425 1.00 19.23 ? 655 ASN B ND2 1 ATOM 4519 N N . ASP A 1 600 ? 43.197 143.882 -80.583 1.00 18.21 ? 656 ASP B N 1 ATOM 4520 C CA . ASP A 1 600 ? 43.845 144.738 -81.580 1.00 17.42 ? 656 ASP B CA 1 ATOM 4521 C C . ASP A 1 600 ? 45.252 144.298 -82.017 1.00 18.11 ? 656 ASP B C 1 ATOM 4522 O O . ASP A 1 600 ? 46.035 145.134 -82.429 1.00 30.19 ? 656 ASP B O 1 ATOM 4523 C CB . ASP A 1 600 ? 43.822 146.208 -81.163 1.00 32.98 ? 656 ASP B CB 1 ATOM 4524 C CG . ASP A 1 600 ? 42.423 146.704 -80.881 1.00 39.14 ? 656 ASP B CG 1 ATOM 4525 O OD1 . ASP A 1 600 ? 41.572 146.664 -81.800 1.00 16.97 ? 656 ASP B OD1 1 ATOM 4526 O OD2 . ASP A 1 600 ? 42.174 147.131 -79.733 1.00 45.49 ? 656 ASP B OD2 1 ATOM 4527 N N . PHE A 1 601 ? 45.631 143.053 -81.758 1.00 17.84 ? 657 PHE B N 1 ATOM 4528 C CA . PHE A 1 601 ? 46.918 142.521 -82.219 1.00 18.48 ? 657 PHE B CA 1 ATOM 4529 C C . PHE A 1 601 ? 47.157 142.692 -83.756 1.00 28.10 ? 657 PHE B C 1 ATOM 4530 O O . PHE A 1 601 ? 46.233 142.592 -84.573 1.00 24.23 ? 657 PHE B O 1 ATOM 4531 C CB . PHE A 1 601 ? 47.055 141.026 -81.849 1.00 18.00 ? 657 PHE B CB 1 ATOM 4532 C CG . PHE A 1 601 ? 47.086 140.741 -80.362 1.00 30.45 ? 657 PHE B CG 1 ATOM 4533 C CD1 . PHE A 1 601 ? 48.115 141.224 -79.559 1.00 27.69 ? 657 PHE B CD1 1 ATOM 4534 C CD2 . PHE A 1 601 ? 46.106 139.947 -79.773 1.00 29.89 ? 657 PHE B CD2 1 ATOM 4535 C CE1 . PHE A 1 601 ? 48.150 140.942 -78.209 1.00 24.72 ? 657 PHE B CE1 1 ATOM 4536 C CE2 . PHE A 1 601 ? 46.132 139.662 -78.419 1.00 28.88 ? 657 PHE B CE2 1 ATOM 4537 C CZ . PHE A 1 601 ? 47.156 140.158 -77.633 1.00 27.56 ? 657 PHE B CZ 1 ATOM 4538 N N . SER A 1 602 ? 48.402 142.961 -84.139 1.00 23.77 ? 658 SER B N 1 ATOM 4539 C CA . SER A 1 602 ? 48.777 143.001 -85.546 1.00 20.25 ? 658 SER B CA 1 ATOM 4540 C C . SER A 1 602 ? 50.186 142.448 -85.694 1.00 21.86 ? 658 SER B C 1 ATOM 4541 O O . SER A 1 602 ? 50.925 142.329 -84.710 1.00 23.18 ? 658 SER B O 1 ATOM 4542 C CB . SER A 1 602 ? 48.694 144.425 -86.120 1.00 20.79 ? 658 SER B CB 1 ATOM 4543 O OG . SER A 1 602 ? 49.825 145.199 -85.789 1.00 56.12 ? 658 SER B OG 1 ATOM 4544 N N . GLY A 1 603 ? 50.573 142.121 -86.918 1.00 23.42 ? 659 GLY B N 1 ATOM 4545 C CA . GLY A 1 603 ? 51.884 141.544 -87.128 1.00 22.07 ? 659 GLY B CA 1 ATOM 4546 C C . GLY A 1 603 ? 51.857 140.092 -87.541 1.00 21.67 ? 659 GLY B C 1 ATOM 4547 O O . GLY A 1 603 ? 50.817 139.406 -87.531 1.00 22.86 ? 659 GLY B O 1 ATOM 4548 N N . ASP A 1 604 ? 53.013 139.615 -87.958 1.00 22.41 ? 660 ASP B N 1 ATOM 4549 C CA . ASP A 1 604 ? 53.086 138.256 -88.446 1.00 36.64 ? 660 ASP B CA 1 ATOM 4550 C C . ASP A 1 604 ? 53.497 137.280 -87.367 1.00 35.27 ? 660 ASP B C 1 ATOM 4551 O O . ASP A 1 604 ? 54.323 137.573 -86.511 1.00 37.34 ? 660 ASP B O 1 ATOM 4552 C CB . ASP A 1 604 ? 54.002 138.138 -89.662 1.00 37.34 ? 660 ASP B CB 1 ATOM 4553 C CG . ASP A 1 604 ? 55.401 138.597 -89.380 1.00 41.99 ? 660 ASP B CG 1 ATOM 4554 O OD1 . ASP A 1 604 ? 55.642 139.819 -89.401 1.00 50.41 ? 660 ASP B OD1 1 ATOM 4555 O OD2 . ASP A 1 604 ? 56.268 137.737 -89.146 1.00 49.92 ? 660 ASP B OD2 1 ATOM 4556 N N . LEU A 1 605 ? 52.862 136.123 -87.415 1.00 38.37 ? 661 LEU B N 1 ATOM 4557 C CA . LEU A 1 605 ? 53.246 134.980 -86.632 1.00 43.65 ? 661 LEU B CA 1 ATOM 4558 C C . LEU A 1 605 ? 54.252 134.183 -87.462 1.00 56.75 ? 661 LEU B C 1 ATOM 4559 O O . LEU A 1 605 ? 54.234 134.236 -88.703 1.00 54.75 ? 661 LEU B O 1 ATOM 4560 C CB . LEU A 1 605 ? 52.012 134.125 -86.370 1.00 37.65 ? 661 LEU B CB 1 ATOM 4561 C CG . LEU A 1 605 ? 50.745 134.867 -85.948 1.00 28.13 ? 661 LEU B CG 1 ATOM 4562 C CD1 . LEU A 1 605 ? 49.516 134.004 -86.166 1.00 21.10 ? 661 LEU B CD1 1 ATOM 4563 C CD2 . LEU A 1 605 ? 50.845 135.297 -84.510 1.00 25.65 ? 661 LEU B CD2 1 ATOM 4564 N N . PRO A 1 606 ? 55.139 133.441 -86.778 1.00 59.10 ? 662 PRO B N 1 ATOM 4565 C CA . PRO A 1 606 ? 56.028 132.484 -87.444 1.00 58.13 ? 662 PRO B CA 1 ATOM 4566 C C . PRO A 1 606 ? 55.202 131.325 -88.005 1.00 58.36 ? 662 PRO B C 1 ATOM 4567 O O . PRO A 1 606 ? 54.041 131.168 -87.624 1.00 46.38 ? 662 PRO B O 1 ATOM 4568 C CB . PRO A 1 606 ? 56.922 131.997 -86.303 1.00 49.10 ? 662 PRO B CB 1 ATOM 4569 C CG . PRO A 1 606 ? 56.076 132.165 -85.083 1.00 47.18 ? 662 PRO B CG 1 ATOM 4570 C CD . PRO A 1 606 ? 55.297 133.418 -85.312 1.00 46.67 ? 662 PRO B CD 1 ATOM 4571 N N . ASN A 1 607 ? 55.790 130.527 -88.889 1.00 63.33 ? 663 ASN B N 1 ATOM 4572 C CA . ASN A 1 607 ? 55.092 129.373 -89.452 1.00 65.47 ? 663 ASN B CA 1 ATOM 4573 C C . ASN A 1 607 ? 55.246 128.089 -88.611 1.00 74.94 ? 663 ASN B C 1 ATOM 4574 O O . ASN A 1 607 ? 54.874 127.004 -89.064 1.00 75.37 ? 663 ASN B O 1 ATOM 4575 C CB . ASN A 1 607 ? 55.488 129.131 -90.911 1.00 59.14 ? 663 ASN B CB 1 ATOM 4576 C CG . ASN A 1 607 ? 54.348 128.548 -91.737 1.00 56.05 ? 663 ASN B CG 1 ATOM 4577 O OD1 . ASN A 1 607 ? 54.300 128.712 -92.958 1.00 54.77 ? 663 ASN B OD1 1 ATOM 4578 N ND2 . ASN A 1 607 ? 53.422 127.871 -91.072 1.00 54.66 ? 663 ASN B ND2 1 ATOM 4579 N N . THR A 1 608 ? 55.815 128.217 -87.407 1.00 75.24 ? 664 THR B N 1 ATOM 4580 C CA . THR A 1 608 ? 55.989 127.085 -86.494 1.00 67.63 ? 664 THR B CA 1 ATOM 4581 C C . THR A 1 608 ? 54.651 126.375 -86.279 1.00 66.87 ? 664 THR B C 1 ATOM 4582 O O . THR A 1 608 ? 53.596 126.988 -86.445 1.00 67.93 ? 664 THR B O 1 ATOM 4583 C CB . THR A 1 608 ? 56.526 127.541 -85.122 1.00 59.95 ? 664 THR B CB 1 ATOM 4584 O OG1 . THR A 1 608 ? 55.428 127.855 -84.257 1.00 58.04 ? 664 THR B OG1 1 ATOM 4585 C CG2 . THR A 1 608 ? 57.457 128.730 -85.266 1.00 55.75 ? 664 THR B CG2 1 ATOM 4586 N N . PRO A 1 609 ? 54.686 125.076 -85.919 1.00 64.08 ? 665 PRO B N 1 ATOM 4587 C CA . PRO A 1 609 ? 53.432 124.316 -85.973 1.00 63.00 ? 665 PRO B CA 1 ATOM 4588 C C . PRO A 1 609 ? 52.394 124.841 -84.983 1.00 54.57 ? 665 PRO B C 1 ATOM 4589 O O . PRO A 1 609 ? 51.189 124.740 -85.251 1.00 52.00 ? 665 PRO B O 1 ATOM 4590 C CB . PRO A 1 609 ? 53.872 122.902 -85.591 1.00 64.32 ? 665 PRO B CB 1 ATOM 4591 C CG . PRO A 1 609 ? 55.054 123.121 -84.705 1.00 62.03 ? 665 PRO B CG 1 ATOM 4592 C CD . PRO A 1 609 ? 55.766 124.304 -85.275 1.00 59.25 ? 665 PRO B CD 1 ATOM 4593 N N . PHE A 1 610 ? 52.848 125.413 -83.870 1.00 44.06 ? 666 PHE B N 1 ATOM 4594 C CA . PHE A 1 610 ? 51.902 125.918 -82.887 1.00 44.68 ? 666 PHE B CA 1 ATOM 4595 C C . PHE A 1 610 ? 51.114 127.125 -83.371 1.00 51.21 ? 666 PHE B C 1 ATOM 4596 O O . PHE A 1 610 ? 49.893 127.173 -83.237 1.00 50.59 ? 666 PHE B O 1 ATOM 4597 C CB . PHE A 1 610 ? 52.567 126.264 -81.569 1.00 43.92 ? 666 PHE B CB 1 ATOM 4598 C CG . PHE A 1 610 ? 51.595 126.736 -80.540 1.00 46.63 ? 666 PHE B CG 1 ATOM 4599 C CD1 . PHE A 1 610 ? 50.530 125.930 -80.167 1.00 43.12 ? 666 PHE B CD1 1 ATOM 4600 C CD2 . PHE A 1 610 ? 51.707 127.998 -79.978 1.00 50.32 ? 666 PHE B CD2 1 ATOM 4601 C CE1 . PHE A 1 610 ? 49.615 126.357 -79.222 1.00 42.93 ? 666 PHE B CE1 1 ATOM 4602 C CE2 . PHE A 1 610 ? 50.791 128.434 -79.034 1.00 47.43 ? 666 PHE B CE2 1 ATOM 4603 C CZ . PHE A 1 610 ? 49.743 127.611 -78.656 1.00 44.51 ? 666 PHE B CZ 1 ATOM 4604 N N . PHE A 1 611 ? 51.808 128.112 -83.919 1.00 54.06 ? 667 PHE B N 1 ATOM 4605 C CA . PHE A 1 611 ? 51.110 129.283 -84.423 1.00 50.86 ? 667 PHE B CA 1 ATOM 4606 C C . PHE A 1 611 ? 50.302 128.962 -85.676 1.00 55.38 ? 667 PHE B C 1 ATOM 4607 O O . PHE A 1 611 ? 49.268 129.577 -85.929 1.00 63.41 ? 667 PHE B O 1 ATOM 4608 C CB . PHE A 1 611 ? 52.070 130.448 -84.622 1.00 45.41 ? 667 PHE B CB 1 ATOM 4609 C CG . PHE A 1 611 ? 52.598 130.995 -83.338 1.00 48.03 ? 667 PHE B CG 1 ATOM 4610 C CD1 . PHE A 1 611 ? 51.903 131.973 -82.656 1.00 49.49 ? 667 PHE B CD1 1 ATOM 4611 C CD2 . PHE A 1 611 ? 53.766 130.501 -82.786 1.00 58.51 ? 667 PHE B CD2 1 ATOM 4612 C CE1 . PHE A 1 611 ? 52.373 132.471 -81.456 1.00 53.04 ? 667 PHE B CE1 1 ATOM 4613 C CE2 . PHE A 1 611 ? 54.247 130.994 -81.586 1.00 63.20 ? 667 PHE B CE2 1 ATOM 4614 C CZ . PHE A 1 611 ? 53.548 131.981 -80.920 1.00 60.82 ? 667 PHE B CZ 1 ATOM 4615 N N . ARG A 1 612 ? 50.752 127.975 -86.441 1.00 51.39 ? 668 ARG B N 1 ATOM 4616 C CA . ARG A 1 612 ? 49.971 127.492 -87.570 1.00 53.06 ? 668 ARG B CA 1 ATOM 4617 C C . ARG A 1 612 ? 48.688 126.821 -87.075 1.00 59.27 ? 668 ARG B C 1 ATOM 4618 O O . ARG A 1 612 ? 47.664 126.828 -87.763 1.00 62.35 ? 668 ARG B O 1 ATOM 4619 C CB . ARG A 1 612 ? 50.796 126.517 -88.407 1.00 60.19 ? 668 ARG B CB 1 ATOM 4620 C CG . ARG A 1 612 ? 50.076 125.973 -89.646 1.00 66.69 ? 668 ARG B CG 1 ATOM 4621 C CD . ARG A 1 612 ? 49.891 127.034 -90.729 1.00 66.54 ? 668 ARG B CD 1 ATOM 4622 N NE . ARG A 1 612 ? 49.525 126.431 -92.008 1.00 68.96 ? 668 ARG B NE 1 ATOM 4623 C CZ . ARG A 1 612 ? 48.279 126.319 -92.462 1.00 70.28 ? 668 ARG B CZ 1 ATOM 4624 N NH1 . ARG A 1 612 ? 47.259 126.778 -91.744 1.00 68.44 ? 668 ARG B NH1 1 ATOM 4625 N NH2 . ARG A 1 612 ? 48.056 125.752 -93.641 1.00 69.95 ? 668 ARG B NH2 1 ATOM 4626 N N . ARG A 1 613 ? 48.746 126.248 -85.874 1.00 61.18 ? 669 ARG B N 1 ATOM 4627 C CA . ARG A 1 613 ? 47.569 125.634 -85.262 1.00 61.12 ? 669 ARG B CA 1 ATOM 4628 C C . ARG A 1 613 ? 46.418 126.631 -85.041 1.00 56.36 ? 669 ARG B C 1 ATOM 4629 O O . ARG A 1 613 ? 45.249 126.256 -85.157 1.00 60.24 ? 669 ARG B O 1 ATOM 4630 C CB . ARG A 1 613 ? 47.951 124.929 -83.946 1.00 68.29 ? 669 ARG B CB 1 ATOM 4631 C CG . ARG A 1 613 ? 46.830 124.841 -82.893 1.00 72.71 ? 669 ARG B CG 1 ATOM 4632 C CD . ARG A 1 613 ? 47.380 124.491 -81.506 1.00 74.39 ? 669 ARG B CD 1 ATOM 4633 N NE . ARG A 1 613 ? 46.379 124.621 -80.442 1.00 74.25 ? 669 ARG B NE 1 ATOM 4634 C CZ . ARG A 1 613 ? 46.085 125.763 -79.817 1.00 71.57 ? 669 ARG B CZ 1 ATOM 4635 N NH1 . ARG A 1 613 ? 45.168 125.790 -78.859 1.00 65.01 ? 669 ARG B NH1 1 ATOM 4636 N NH2 . ARG A 1 613 ? 46.701 126.886 -80.151 1.00 74.81 ? 669 ARG B NH2 1 ATOM 4637 N N . LEU A 1 614 ? 46.740 127.892 -84.739 1.00 45.15 ? 670 LEU B N 1 ATOM 4638 C CA . LEU A 1 614 ? 45.709 128.885 -84.392 1.00 34.43 ? 670 LEU B CA 1 ATOM 4639 C C . LEU A 1 614 ? 44.669 129.082 -85.488 1.00 31.21 ? 670 LEU B C 1 ATOM 4640 O O . LEU A 1 614 ? 45.015 129.366 -86.641 1.00 38.68 ? 670 LEU B O 1 ATOM 4641 C CB . LEU A 1 614 ? 46.315 130.249 -84.054 1.00 27.00 ? 670 LEU B CB 1 ATOM 4642 C CG . LEU A 1 614 ? 47.293 130.385 -82.901 1.00 27.77 ? 670 LEU B CG 1 ATOM 4643 C CD1 . LEU A 1 614 ? 47.653 131.847 -82.709 1.00 27.51 ? 670 LEU B CD1 1 ATOM 4644 C CD2 . LEU A 1 614 ? 46.702 129.795 -81.637 1.00 24.62 ? 670 LEU B CD2 1 ATOM 4645 N N . PRO A 1 615 ? 43.388 128.977 -85.115 1.00 24.73 ? 671 PRO B N 1 ATOM 4646 C CA . PRO A 1 615 ? 42.278 129.110 -86.066 1.00 23.35 ? 671 PRO B CA 1 ATOM 4647 C C . PRO A 1 615 ? 42.281 130.457 -86.785 1.00 28.22 ? 671 PRO B C 1 ATOM 4648 O O . PRO A 1 615 ? 42.489 131.505 -86.182 1.00 29.68 ? 671 PRO B O 1 ATOM 4649 C CB . PRO A 1 615 ? 41.021 128.945 -85.194 1.00 24.21 ? 671 PRO B CB 1 ATOM 4650 C CG . PRO A 1 615 ? 41.471 129.160 -83.774 1.00 23.93 ? 671 PRO B CG 1 ATOM 4651 C CD . PRO A 1 615 ? 42.941 128.880 -83.708 1.00 28.22 ? 671 PRO B CD 1 ATOM 4652 N N . LEU A 1 616 ? 42.063 130.410 -88.092 1.00 37.23 ? 672 LEU B N 1 ATOM 4653 C CA . LEU A 1 616 ? 42.078 131.603 -88.921 1.00 31.37 ? 672 LEU B CA 1 ATOM 4654 C C . LEU A 1 616 ? 41.034 132.608 -88.446 1.00 27.54 ? 672 LEU B C 1 ATOM 4655 O O . LEU A 1 616 ? 41.204 133.821 -88.600 1.00 33.70 ? 672 LEU B O 1 ATOM 4656 C CB . LEU A 1 616 ? 41.852 131.228 -90.391 1.00 22.07 ? 672 LEU B CB 1 ATOM 4657 C CG . LEU A 1 616 ? 42.186 132.292 -91.443 1.00 23.79 ? 672 LEU B CG 1 ATOM 4658 C CD1 . LEU A 1 616 ? 43.333 133.225 -91.008 1.00 15.83 ? 672 LEU B CD1 1 ATOM 4659 C CD2 . LEU A 1 616 ? 42.530 131.620 -92.764 1.00 25.66 ? 672 LEU B CD2 1 ATOM 4660 N N . SER A 1 617 ? 39.961 132.098 -87.854 1.00 22.34 ? 673 SER B N 1 ATOM 4661 C CA . SER A 1 617 ? 38.914 132.956 -87.311 1.00 30.44 ? 673 SER B CA 1 ATOM 4662 C C . SER A 1 617 ? 39.403 133.734 -86.093 1.00 32.07 ? 673 SER B C 1 ATOM 4663 O O . SER A 1 617 ? 38.888 134.815 -85.807 1.00 33.16 ? 673 SER B O 1 ATOM 4664 C CB . SER A 1 617 ? 37.678 132.133 -86.945 1.00 34.79 ? 673 SER B CB 1 ATOM 4665 O OG . SER A 1 617 ? 38.052 130.848 -86.466 1.00 41.40 ? 673 SER B OG 1 ATOM 4666 N N . ASP A 1 618 ? 40.381 133.182 -85.372 1.00 28.51 ? 674 ASP B N 1 ATOM 4667 C CA . ASP A 1 618 ? 40.992 133.884 -84.240 1.00 26.72 ? 674 ASP B CA 1 ATOM 4668 C C . ASP A 1 618 ? 41.830 135.053 -84.745 1.00 27.27 ? 674 ASP B C 1 ATOM 4669 O O . ASP A 1 618 ? 41.827 136.123 -84.144 1.00 29.85 ? 674 ASP B O 1 ATOM 4670 C CB . ASP A 1 618 ? 41.856 132.942 -83.400 1.00 33.28 ? 674 ASP B CB 1 ATOM 4671 C CG . ASP A 1 618 ? 41.048 132.146 -82.384 1.00 43.27 ? 674 ASP B CG 1 ATOM 4672 O OD1 . ASP A 1 618 ? 39.802 132.168 -82.467 1.00 44.70 ? 674 ASP B OD1 1 ATOM 4673 O OD2 . ASP A 1 618 ? 41.660 131.497 -81.500 1.00 47.84 ? 674 ASP B OD2 1 ATOM 4674 N N . LEU A 1 619 ? 42.540 134.842 -85.853 1.00 25.59 ? 675 LEU B N 1 ATOM 4675 C CA . LEU A 1 619 ? 43.269 135.921 -86.522 1.00 29.40 ? 675 LEU B CA 1 ATOM 4676 C C . LEU A 1 619 ? 42.332 136.984 -87.112 1.00 26.55 ? 675 LEU B C 1 ATOM 4677 O O . LEU A 1 619 ? 42.683 138.156 -87.179 1.00 30.19 ? 675 LEU B O 1 ATOM 4678 C CB . LEU A 1 619 ? 44.160 135.372 -87.643 1.00 30.14 ? 675 LEU B CB 1 ATOM 4679 C CG . LEU A 1 619 ? 45.142 134.254 -87.289 1.00 32.07 ? 675 LEU B CG 1 ATOM 4680 C CD1 . LEU A 1 619 ? 45.994 133.864 -88.495 1.00 16.39 ? 675 LEU B CD1 1 ATOM 4681 C CD2 . LEU A 1 619 ? 46.002 134.698 -86.150 1.00 16.13 ? 675 LEU B CD2 1 ATOM 4682 N N . ALA A 1 620 ? 41.142 136.577 -87.539 1.00 23.61 ? 676 ALA B N 1 ATOM 4683 C CA . ALA A 1 620 ? 40.229 137.492 -88.236 1.00 19.73 ? 676 ALA B CA 1 ATOM 4684 C C . ALA A 1 620 ? 39.565 138.538 -87.327 1.00 19.20 ? 676 ALA B C 1 ATOM 4685 O O . ALA A 1 620 ? 39.071 139.570 -87.804 1.00 16.63 ? 676 ALA B O 1 ATOM 4686 C CB . ALA A 1 620 ? 39.177 136.701 -89.000 1.00 13.42 ? 676 ALA B CB 1 ATOM 4687 N N . SER A 1 621 ? 39.556 138.271 -86.023 1.00 18.65 ? 677 SER B N 1 ATOM 4688 C CA . SER A 1 621 ? 39.021 139.213 -85.037 1.00 14.73 ? 677 SER B CA 1 ATOM 4689 C C . SER A 1 621 ? 40.063 140.206 -84.499 1.00 19.88 ? 677 SER B C 1 ATOM 4690 O O . SER A 1 621 ? 39.792 140.927 -83.539 1.00 26.88 ? 677 SER B O 1 ATOM 4691 C CB . SER A 1 621 ? 38.359 138.468 -83.877 1.00 18.16 ? 677 SER B CB 1 ATOM 4692 O OG . SER A 1 621 ? 39.258 137.544 -83.286 1.00 27.51 ? 677 SER B OG 1 ATOM 4693 N N . ASN A 1 622 ? 41.264 140.198 -85.072 1.00 14.85 ? 678 ASN B N 1 ATOM 4694 C CA . ASN A 1 622 ? 42.293 141.163 -84.708 1.00 15.68 ? 678 ASN B CA 1 ATOM 4695 C C . ASN A 1 622 ? 42.530 142.279 -85.731 1.00 17.98 ? 678 ASN B C 1 ATOM 4696 O O . ASN A 1 622 ? 41.784 142.426 -86.688 1.00 20.76 ? 678 ASN B O 1 ATOM 4697 C CB . ASN A 1 622 ? 43.585 140.456 -84.335 1.00 26.50 ? 678 ASN B CB 1 ATOM 4698 C CG . ASN A 1 622 ? 43.517 139.846 -82.951 1.00 36.41 ? 678 ASN B CG 1 ATOM 4699 O OD1 . ASN A 1 622 ? 43.931 140.465 -81.969 1.00 37.92 ? 678 ASN B OD1 1 ATOM 4700 N ND2 . ASN A 1 622 ? 42.969 138.636 -82.860 1.00 33.97 ? 678 ASN B ND2 1 ATOM 4701 N N . ARG A 1 623 ? 43.548 143.094 -85.503 1.00 17.16 ? 679 ARG B N 1 ATOM 4702 C CA . ARG A 1 623 ? 43.813 144.214 -86.394 1.00 26.38 ? 679 ARG B CA 1 ATOM 4703 C C . ARG A 1 623 ? 44.626 143.851 -87.640 1.00 24.12 ? 679 ARG B C 1 ATOM 4704 O O . ARG A 1 623 ? 44.212 144.136 -88.752 1.00 32.31 ? 679 ARG B O 1 ATOM 4705 C CB . ARG A 1 623 ? 44.510 145.342 -85.630 1.00 36.24 ? 679 ARG B CB 1 ATOM 4706 C CG . ARG A 1 623 ? 44.794 146.556 -86.481 1.00 39.00 ? 679 ARG B CG 1 ATOM 4707 C CD . ARG A 1 623 ? 45.530 147.601 -85.691 1.00 43.94 ? 679 ARG B CD 1 ATOM 4708 N NE . ARG A 1 623 ? 44.704 148.147 -84.623 1.00 51.89 ? 679 ARG B NE 1 ATOM 4709 C CZ . ARG A 1 623 ? 45.160 148.976 -83.693 1.00 59.27 ? 679 ARG B CZ 1 ATOM 4710 N NH1 . ARG A 1 623 ? 46.441 149.345 -83.701 1.00 58.96 ? 679 ARG B NH1 1 ATOM 4711 N NH2 . ARG A 1 623 ? 44.341 149.429 -82.751 1.00 62.56 ? 679 ARG B NH2 1 ATOM 4712 N N . GLY A 1 624 ? 45.852 143.396 -87.424 1.00 22.88 ? 680 GLY B N 1 ATOM 4713 C CA . GLY A 1 624 ? 46.768 142.912 -88.454 1.00 25.87 ? 680 GLY B CA 1 ATOM 4714 C C . GLY A 1 624 ? 47.402 141.518 -88.457 1.00 19.40 ? 680 GLY B C 1 ATOM 4715 O O . GLY A 1 624 ? 48.515 141.419 -88.965 1.00 20.16 ? 680 GLY B O 1 ATOM 4716 N N . LEU A 1 625 ? 46.861 140.516 -87.768 1.00 18.62 ? 681 LEU B N 1 ATOM 4717 C CA . LEU A 1 625 ? 47.576 139.231 -87.613 1.00 18.64 ? 681 LEU B CA 1 ATOM 4718 C C . LEU A 1 625 ? 47.589 138.321 -88.853 1.00 18.63 ? 681 LEU B C 1 ATOM 4719 O O . LEU A 1 625 ? 46.553 138.102 -89.474 1.00 18.05 ? 681 LEU B O 1 ATOM 4720 C CB . LEU A 1 625 ? 47.017 138.426 -86.435 1.00 17.84 ? 681 LEU B CB 1 ATOM 4721 C CG . LEU A 1 625 ? 47.162 138.995 -85.026 1.00 26.72 ? 681 LEU B CG 1 ATOM 4722 C CD1 . LEU A 1 625 ? 46.453 138.094 -84.033 1.00 21.82 ? 681 LEU B CD1 1 ATOM 4723 C CD2 . LEU A 1 625 ? 48.639 139.175 -84.661 1.00 25.78 ? 681 LEU B CD2 1 ATOM 4724 N N . TYR A 1 626 ? 48.758 137.778 -89.204 1.00 19.28 ? 682 TYR B N 1 ATOM 4725 C CA . TYR A 1 626 ? 48.804 136.826 -90.328 1.00 31.20 ? 682 TYR B CA 1 ATOM 4726 C C . TYR A 1 626 ? 49.996 135.895 -90.210 1.00 19.81 ? 682 TYR B C 1 ATOM 4727 O O . TYR A 1 626 ? 50.971 136.241 -89.562 1.00 21.57 ? 682 TYR B O 1 ATOM 4728 C CB . TYR A 1 626 ? 48.839 137.548 -91.700 1.00 19.83 ? 682 TYR B CB 1 ATOM 4729 C CG . TYR A 1 626 ? 50.108 138.333 -91.946 1.00 20.92 ? 682 TYR B CG 1 ATOM 4730 C CD1 . TYR A 1 626 ? 50.285 139.581 -91.369 1.00 25.92 ? 682 TYR B CD1 1 ATOM 4731 C CD2 . TYR A 1 626 ? 51.142 137.821 -92.723 1.00 21.66 ? 682 TYR B CD2 1 ATOM 4732 C CE1 . TYR A 1 626 ? 51.445 140.309 -91.575 1.00 28.52 ? 682 TYR B CE1 1 ATOM 4733 C CE2 . TYR A 1 626 ? 52.307 138.538 -92.915 1.00 22.68 ? 682 TYR B CE2 1 ATOM 4734 C CZ . TYR A 1 626 ? 52.448 139.786 -92.340 1.00 22.98 ? 682 TYR B CZ 1 ATOM 4735 O OH . TYR A 1 626 ? 53.585 140.532 -92.498 1.00 24.02 ? 682 TYR B OH 1 ATOM 4736 N N . ILE A 1 627 ? 49.928 134.727 -90.849 1.00 25.47 ? 683 ILE B N 1 ATOM 4737 C CA . ILE A 1 627 ? 51.092 133.851 -90.922 1.00 26.07 ? 683 ILE B CA 1 ATOM 4738 C C . ILE A 1 627 ? 51.995 134.301 -92.066 1.00 29.44 ? 683 ILE B C 1 ATOM 4739 O O . ILE A 1 627 ? 51.569 134.364 -93.212 1.00 26.18 ? 683 ILE B O 1 ATOM 4740 C CB . ILE A 1 627 ? 50.718 132.365 -91.126 1.00 26.42 ? 683 ILE B CB 1 ATOM 4741 C CG1 . ILE A 1 627 ? 50.401 131.684 -89.797 1.00 26.02 ? 683 ILE B CG1 1 ATOM 4742 C CG2 . ILE A 1 627 ? 51.895 131.615 -91.721 1.00 31.14 ? 683 ILE B CG2 1 ATOM 4743 C CD1 . ILE A 1 627 ? 49.008 131.907 -89.284 1.00 31.10 ? 683 ILE B CD1 1 ATOM 4744 N N . SER A 1 628 ? 53.240 134.639 -91.758 1.00 46.99 ? 684 SER B N 1 ATOM 4745 C CA . SER A 1 628 ? 54.193 134.932 -92.822 1.00 60.42 ? 684 SER B CA 1 ATOM 4746 C C . SER A 1 628 ? 55.012 133.682 -93.084 1.00 66.97 ? 684 SER B C 1 ATOM 4747 O O . SER A 1 628 ? 55.464 133.012 -92.153 1.00 66.83 ? 684 SER B O 1 ATOM 4748 C CB . SER A 1 628 ? 55.104 136.120 -92.475 1.00 60.09 ? 684 SER B CB 1 ATOM 4749 O OG . SER A 1 628 ? 56.173 135.743 -91.621 1.00 52.78 ? 684 SER B OG 1 ATOM 4750 N N . ASN A 1 629 ? 55.185 133.354 -94.355 1.00 73.05 ? 685 ASN B N 1 ATOM 4751 C CA . ASN A 1 629 ? 55.991 132.199 -94.711 1.00 83.18 ? 685 ASN B CA 1 ATOM 4752 C C . ASN A 1 629 ? 57.479 132.574 -94.805 1.00 86.75 ? 685 ASN B C 1 ATOM 4753 O O . ASN A 1 629 ? 57.860 133.502 -95.527 1.00 81.31 ? 685 ASN B O 1 ATOM 4754 C CB . ASN A 1 629 ? 55.449 131.537 -95.983 1.00 85.49 ? 685 ASN B CB 1 ATOM 4755 C CG . ASN A 1 629 ? 54.017 131.024 -95.805 1.00 83.46 ? 685 ASN B CG 1 ATOM 4756 O OD1 . ASN A 1 629 ? 53.096 131.447 -96.504 1.00 83.86 ? 685 ASN B OD1 1 ATOM 4757 N ND2 . ASN A 1 629 ? 53.832 130.115 -94.857 1.00 81.80 ? 685 ASN B ND2 1 ATOM 4758 N N . ALA A 1 630 ? 58.305 131.848 -94.050 1.00 92.63 ? 686 ALA B N 1 ATOM 4759 C CA . ALA A 1 630 ? 59.712 132.204 -93.830 1.00 96.35 ? 686 ALA B CA 1 ATOM 4760 C C . ALA A 1 630 ? 60.589 132.122 -95.091 1.00 100.79 ? 686 ALA B C 1 ATOM 4761 O O . ALA A 1 630 ? 60.213 131.489 -96.081 1.00 98.62 ? 686 ALA B O 1 ATOM 4762 C CB . ALA A 1 630 ? 60.306 131.367 -92.691 1.00 91.16 ? 686 ALA B CB 1 ATOM 4763 N N . ASP B 2 1 ? 50.768 89.476 -46.729 1.00 35.87 ? 44 ASP A N 1 ATOM 4764 C CA . ASP B 2 1 ? 49.739 88.936 -45.853 1.00 34.89 ? 44 ASP A CA 1 ATOM 4765 C C . ASP B 2 1 ? 48.347 89.385 -46.287 1.00 30.32 ? 44 ASP A C 1 ATOM 4766 O O . ASP B 2 1 ? 48.146 90.539 -46.678 1.00 32.79 ? 44 ASP A O 1 ATOM 4767 C CB . ASP B 2 1 ? 50.011 89.356 -44.413 1.00 40.85 ? 44 ASP A CB 1 ATOM 4768 C CG . ASP B 2 1 ? 51.277 88.738 -43.860 1.00 48.32 ? 44 ASP A CG 1 ATOM 4769 O OD1 . ASP B 2 1 ? 52.161 88.356 -44.667 1.00 51.39 ? 44 ASP A OD1 1 ATOM 4770 O OD2 . ASP B 2 1 ? 51.384 88.632 -42.619 1.00 50.44 ? 44 ASP A OD2 1 HETATM 4771 N N . PTR B 2 2 ? 47.384 88.472 -46.231 1.00 21.06 ? 45 PTR A N 1 HETATM 4772 C CA . PTR B 2 2 ? 46.030 88.819 -46.644 1.00 21.62 ? 45 PTR A CA 1 HETATM 4773 C C . PTR B 2 2 ? 45.393 89.722 -45.588 1.00 24.54 ? 45 PTR A C 1 HETATM 4774 O O . PTR B 2 2 ? 45.789 89.700 -44.417 1.00 12.66 ? 45 PTR A O 1 HETATM 4775 C CB . PTR B 2 2 ? 45.165 87.612 -47.044 1.00 18.09 ? 45 PTR A CB 1 HETATM 4776 C CG . PTR B 2 2 ? 44.612 86.732 -45.926 1.00 12.48 ? 45 PTR A CG 1 HETATM 4777 C CD1 . PTR B 2 2 ? 43.331 86.929 -45.413 1.00 14.32 ? 45 PTR A CD1 1 HETATM 4778 C CD2 . PTR B 2 2 ? 45.339 85.658 -45.442 1.00 15.63 ? 45 PTR A CD2 1 HETATM 4779 C CE1 . PTR B 2 2 ? 42.817 86.101 -44.420 1.00 14.54 ? 45 PTR A CE1 1 HETATM 4780 C CE2 . PTR B 2 2 ? 44.831 84.829 -44.453 1.00 15.27 ? 45 PTR A CE2 1 HETATM 4781 C CZ . PTR B 2 2 ? 43.573 85.044 -43.949 1.00 12.15 ? 45 PTR A CZ 1 HETATM 4782 O OH . PTR B 2 2 ? 43.120 84.244 -43.015 1.00 24.26 ? 45 PTR A OH 1 HETATM 4783 P P . PTR B 2 2 ? 42.232 82.928 -43.338 1.00 11.79 ? 45 PTR A P 1 HETATM 4784 O O1P . PTR B 2 2 ? 41.207 83.195 -44.436 1.00 15.15 ? 45 PTR A O1P 1 HETATM 4785 O O2P . PTR B 2 2 ? 43.133 81.848 -43.801 1.00 16.28 ? 45 PTR A O2P 1 HETATM 4786 O O3P . PTR B 2 2 ? 41.493 82.507 -42.060 1.00 17.51 ? 45 PTR A O3P 1 ATOM 4787 N N . TRP B 2 3 ? 44.423 90.525 -46.017 1.00 13.83 ? 46 TRP A N 1 ATOM 4788 C CA . TRP B 2 3 ? 43.816 91.498 -45.121 1.00 20.22 ? 46 TRP A CA 1 ATOM 4789 C C . TRP B 2 3 ? 42.809 90.865 -44.155 1.00 19.80 ? 46 TRP A C 1 ATOM 4790 O O . TRP B 2 3 ? 42.074 89.935 -44.510 1.00 18.95 ? 46 TRP A O 1 ATOM 4791 C CB . TRP B 2 3 ? 43.151 92.622 -45.919 1.00 22.07 ? 46 TRP A CB 1 ATOM 4792 C CG . TRP B 2 3 ? 44.100 93.606 -46.528 1.00 23.35 ? 46 TRP A CG 1 ATOM 4793 C CD1 . TRP B 2 3 ? 45.455 93.668 -46.350 1.00 30.65 ? 46 TRP A CD1 1 ATOM 4794 C CD2 . TRP B 2 3 ? 43.763 94.678 -47.416 1.00 28.75 ? 46 TRP A CD2 1 ATOM 4795 N NE1 . TRP B 2 3 ? 45.983 94.712 -47.078 1.00 32.76 ? 46 TRP A NE1 1 ATOM 4796 C CE2 . TRP B 2 3 ? 44.963 95.349 -47.740 1.00 33.73 ? 46 TRP A CE2 1 ATOM 4797 C CE3 . TRP B 2 3 ? 42.561 95.136 -47.972 1.00 33.89 ? 46 TRP A CE3 1 ATOM 4798 C CZ2 . TRP B 2 3 ? 44.995 96.456 -48.591 1.00 33.05 ? 46 TRP A CZ2 1 ATOM 4799 C CZ3 . TRP B 2 3 ? 42.594 96.229 -48.824 1.00 40.35 ? 46 TRP A CZ3 1 ATOM 4800 C CH2 . TRP B 2 3 ? 43.805 96.877 -49.126 1.00 38.22 ? 46 TRP A CH2 1 ATOM 4801 N N . ARG B 2 4 ? 42.786 91.379 -42.931 1.00 22.63 ? 47 ARG A N 1 ATOM 4802 C CA . ARG B 2 4 ? 41.796 90.986 -41.937 1.00 23.32 ? 47 ARG A CA 1 ATOM 4803 C C . ARG B 2 4 ? 40.409 91.427 -42.402 1.00 22.42 ? 47 ARG A C 1 ATOM 4804 O O . ARG B 2 4 ? 40.292 92.286 -43.274 1.00 34.98 ? 47 ARG A O 1 ATOM 4805 C CB . ARG B 2 4 ? 42.123 91.665 -40.617 1.00 34.17 ? 47 ARG A CB 1 ATOM 4806 C CG . ARG B 2 4 ? 42.307 93.173 -40.759 1.00 45.45 ? 47 ARG A CG 1 ATOM 4807 C CD . ARG B 2 4 ? 42.755 93.815 -39.459 1.00 58.00 ? 47 ARG A CD 1 ATOM 4808 N NE . ARG B 2 4 ? 41.634 94.039 -38.556 1.00 72.46 ? 47 ARG A NE 1 ATOM 4809 C CZ . ARG B 2 4 ? 41.673 94.856 -37.509 1.00 85.12 ? 47 ARG A CZ 1 ATOM 4810 N NH1 . ARG B 2 4 ? 42.782 95.531 -37.235 1.00 88.91 ? 47 ARG A NH1 1 ATOM 4811 N NH2 . ARG B 2 4 ? 40.601 95.001 -36.737 1.00 88.68 ? 47 ARG A NH2 1 ATOM 4812 N N . ALA B 2 5 ? 39.366 90.827 -41.837 1.00 15.95 ? 48 ALA A N 1 ATOM 4813 C CA . ALA B 2 5 ? 37.989 91.168 -42.185 1.00 10.55 ? 48 ALA A CA 1 ATOM 4814 C C . ALA B 2 5 ? 37.718 92.651 -42.000 1.00 12.86 ? 48 ALA A C 1 ATOM 4815 O O . ALA B 2 5 ? 38.101 93.222 -40.982 1.00 18.86 ? 48 ALA A O 1 ATOM 4816 C CB . ALA B 2 5 ? 37.007 90.350 -41.370 1.00 7.06 ? 48 ALA A CB 1 ATOM 4817 N N . LYS B 2 6 ? 37.060 93.260 -42.992 1.00 14.50 ? 49 LYS A N 1 ATOM 4818 C CA . LYS B 2 6 ? 36.717 94.690 -42.973 1.00 14.83 ? 49 LYS A CA 1 ATOM 4819 C C . LYS B 2 6 ? 35.295 94.938 -43.446 1.00 8.76 ? 49 LYS A C 1 ATOM 4820 O O . LYS B 2 6 ? 34.738 94.148 -44.211 1.00 15.52 ? 49 LYS A O 1 ATOM 4821 C CB . LYS B 2 6 ? 37.647 95.476 -43.894 1.00 6.59 ? 49 LYS A CB 1 ATOM 4822 C CG . LYS B 2 6 ? 39.075 95.557 -43.445 1.00 21.31 ? 49 LYS A CG 1 ATOM 4823 C CD . LYS B 2 6 ? 39.861 96.481 -44.384 1.00 33.80 ? 49 LYS A CD 1 ATOM 4824 C CE . LYS B 2 6 ? 41.286 96.706 -43.889 1.00 38.47 ? 49 LYS A CE 1 ATOM 4825 N NZ . LYS B 2 6 ? 42.031 95.414 -43.836 1.00 39.09 ? 49 LYS A NZ 1 ATOM 4826 N N . HIS B 2 7 ? 34.709 96.050 -43.032 1.00 12.25 ? 50 HIS A N 1 ATOM 4827 C CA . HIS B 2 7 ? 33.425 96.439 -43.617 1.00 17.01 ? 50 HIS A CA 1 ATOM 4828 C C . HIS B 2 7 ? 33.670 97.232 -44.895 1.00 13.59 ? 50 HIS A C 1 ATOM 4829 O O . HIS B 2 7 ? 34.815 97.595 -45.191 1.00 15.49 ? 50 HIS A O 1 ATOM 4830 C CB . HIS B 2 7 ? 32.589 97.264 -42.622 1.00 20.23 ? 50 HIS A CB 1 ATOM 4831 C CG . HIS B 2 7 ? 33.191 98.590 -42.262 1.00 30.24 ? 50 HIS A CG 1 ATOM 4832 N ND1 . HIS B 2 7 ? 32.622 99.435 -41.335 1.00 38.58 ? 50 HIS A ND1 1 ATOM 4833 C CD2 . HIS B 2 7 ? 34.314 99.214 -42.699 1.00 36.66 ? 50 HIS A CD2 1 ATOM 4834 C CE1 . HIS B 2 7 ? 33.363 100.524 -41.217 1.00 39.26 ? 50 HIS A CE1 1 ATOM 4835 N NE2 . HIS B 2 7 ? 34.396 100.415 -42.031 1.00 39.79 ? 50 HIS A NE2 1 ATOM 4836 N N . HIS B 2 8 ? 32.594 97.536 -45.623 1.00 11.91 ? 51 HIS A N 1 ATOM 4837 C CA . HIS B 2 8 ? 32.652 98.401 -46.800 1.00 10.88 ? 51 HIS A CA 1 ATOM 4838 C C . HIS B 2 8 ? 33.097 99.786 -46.341 1.00 15.51 ? 51 HIS A C 1 ATOM 4839 O O . HIS B 2 8 ? 32.547 100.321 -45.382 1.00 18.15 ? 51 HIS A O 1 ATOM 4840 C CB . HIS B 2 8 ? 31.263 98.492 -47.424 1.00 8.73 ? 51 HIS A CB 1 ATOM 4841 C CG . HIS B 2 8 ? 31.135 99.521 -48.503 1.00 13.73 ? 51 HIS A CG 1 ATOM 4842 N ND1 . HIS B 2 8 ? 30.660 100.798 -48.267 1.00 14.37 ? 51 HIS A ND1 1 ATOM 4843 C CD2 . HIS B 2 8 ? 31.381 99.456 -49.836 1.00 12.17 ? 51 HIS A CD2 1 ATOM 4844 C CE1 . HIS B 2 8 ? 30.636 101.474 -49.401 1.00 8.72 ? 51 HIS A CE1 1 ATOM 4845 N NE2 . HIS B 2 8 ? 31.069 100.687 -50.368 1.00 15.75 ? 51 HIS A NE2 1 ATOM 4846 N N . PRO B 2 9 ? 34.106 100.365 -47.008 1.00 14.21 ? 52 PRO A N 1 ATOM 4847 C CA . PRO B 2 9 ? 34.587 101.695 -46.618 1.00 20.28 ? 52 PRO A CA 1 ATOM 4848 C C . PRO B 2 9 ? 33.500 102.737 -46.857 1.00 26.53 ? 52 PRO A C 1 ATOM 4849 O O . PRO B 2 9 ? 32.824 102.679 -47.881 1.00 23.24 ? 52 PRO A O 1 ATOM 4850 C CB . PRO B 2 9 ? 35.762 101.946 -47.582 1.00 10.13 ? 52 PRO A CB 1 ATOM 4851 C CG . PRO B 2 9 ? 36.112 100.616 -48.139 1.00 5.15 ? 52 PRO A CG 1 ATOM 4852 C CD . PRO B 2 9 ? 34.818 99.858 -48.189 1.00 14.02 ? 52 PRO A CD 1 HETATM 4853 N N . HZP B 2 10 ? 33.322 103.666 -45.925 1.00 28.02 ? 53 HZP A N 1 HETATM 4854 C CA . HZP B 2 10 ? 32.309 104.689 -46.100 1.00 21.36 ? 53 HZP A CA 1 HETATM 4855 C C . HZP B 2 10 ? 32.835 105.801 -46.990 1.00 19.10 ? 53 HZP A C 1 HETATM 4856 O O . HZP B 2 10 ? 34.013 106.133 -46.961 1.00 20.69 ? 53 HZP A O 1 HETATM 4857 C CB . HZP B 2 10 ? 31.968 105.167 -44.700 1.00 22.58 ? 53 HZP A CB 1 HETATM 4858 C CG . HZP B 2 10 ? 32.458 104.058 -43.789 1.00 32.35 ? 53 HZP A CG 1 HETATM 4859 C CD . HZP B 2 10 ? 33.617 103.382 -44.510 1.00 24.91 ? 53 HZP A CD 1 HETATM 4860 O OD1 . HZP B 2 10 ? 32.869 104.587 -42.549 1.00 48.94 ? 53 HZP A OD1 1 ATOM 4861 N N . LYS B 2 11 ? 31.948 106.350 -47.804 1.00 17.03 ? 54 LYS A N 1 ATOM 4862 C CA . LYS B 2 11 ? 32.306 107.381 -48.758 1.00 15.29 ? 54 LYS A CA 1 ATOM 4863 C C . LYS B 2 11 ? 31.411 108.574 -48.441 1.00 18.05 ? 54 LYS A C 1 ATOM 4864 O O . LYS B 2 11 ? 30.191 108.439 -48.296 1.00 15.98 ? 54 LYS A O 1 ATOM 4865 C CB . LYS B 2 11 ? 32.093 106.849 -50.189 1.00 17.68 ? 54 LYS A CB 1 ATOM 4866 C CG . LYS B 2 11 ? 32.415 107.805 -51.365 1.00 22.97 ? 54 LYS A CG 1 ATOM 4867 C CD . LYS B 2 11 ? 32.241 107.135 -52.766 1.00 48.32 ? 54 LYS A CD 1 ATOM 4868 C CE . LYS B 2 11 ? 30.765 106.799 -53.092 1.00 54.70 ? 54 LYS A CE 1 ATOM 4869 N NZ . LYS B 2 11 ? 30.460 106.398 -54.519 1.00 48.17 ? 54 LYS A NZ 1 ATOM 4870 N N . ASN B 2 12 ? 32.013 109.747 -48.316 1.00 19.00 ? 55 ASN A N 1 ATOM 4871 C CA . ASN B 2 12 ? 31.232 110.956 -48.113 1.00 19.11 ? 55 ASN A CA 1 ATOM 4872 C C . ASN B 2 12 ? 31.599 111.973 -49.188 1.00 13.05 ? 55 ASN A C 1 ATOM 4873 O O . ASN B 2 12 ? 32.539 111.770 -49.934 1.00 10.80 ? 55 ASN A O 1 ATOM 4874 C CB . ASN B 2 12 ? 31.381 111.517 -46.678 1.00 20.41 ? 55 ASN A CB 1 ATOM 4875 C CG . ASN B 2 12 ? 32.782 112.054 -46.383 1.00 17.57 ? 55 ASN A CG 1 ATOM 4876 O OD1 . ASN B 2 12 ? 33.507 111.493 -45.560 1.00 15.78 ? 55 ASN A OD1 1 ATOM 4877 N ND2 . ASN B 2 12 ? 33.162 113.157 -47.049 1.00 9.86 ? 55 ASN A ND2 1 ATOM 4878 N N . ASN B 2 13 ? 30.834 113.047 -49.291 1.00 18.42 ? 56 ASN A N 1 ATOM 4879 C CA . ASN B 2 13 ? 31.082 114.050 -50.321 1.00 20.25 ? 56 ASN A CA 1 ATOM 4880 C C . ASN B 2 13 ? 32.113 115.090 -49.915 1.00 22.62 ? 56 ASN A C 1 ATOM 4881 O O . ASN B 2 13 ? 32.655 115.029 -48.805 1.00 19.96 ? 56 ASN A O 1 ATOM 4882 C CB . ASN B 2 13 ? 29.767 114.710 -50.736 1.00 19.85 ? 56 ASN A CB 1 ATOM 4883 C CG . ASN B 2 13 ? 28.866 113.747 -51.481 1.00 19.00 ? 56 ASN A CG 1 ATOM 4884 O OD1 . ASN B 2 13 ? 29.014 113.565 -52.683 1.00 22.35 ? 56 ASN A OD1 1 ATOM 4885 N ND2 . ASN B 2 13 ? 27.969 113.085 -50.762 1.00 17.26 ? 56 ASN A ND2 1 ATOM 4886 O OXT . ASN B 2 13 ? 32.433 115.989 -50.700 1.00 23.86 ? 56 ASN A OXT 1 HETATM 4887 C C1 . NAG C 3 . ? 25.196 129.013 -29.367 1.00 17.83 ? 701 NAG B C1 1 HETATM 4888 C C2 . NAG C 3 . ? 23.901 128.324 -28.929 1.00 22.94 ? 701 NAG B C2 1 HETATM 4889 C C3 . NAG C 3 . ? 22.960 129.418 -28.439 1.00 26.29 ? 701 NAG B C3 1 HETATM 4890 C C4 . NAG C 3 . ? 23.598 130.188 -27.290 1.00 27.64 ? 701 NAG B C4 1 HETATM 4891 C C5 . NAG C 3 . ? 24.887 130.808 -27.815 1.00 24.91 ? 701 NAG B C5 1 HETATM 4892 C C6 . NAG C 3 . ? 25.622 131.756 -26.842 1.00 24.55 ? 701 NAG B C6 1 HETATM 4893 C C7 . NAG C 3 . ? 23.054 126.319 -30.162 1.00 22.39 ? 701 NAG B C7 1 HETATM 4894 C C8 . NAG C 3 . ? 22.404 125.892 -31.446 1.00 21.55 ? 701 NAG B C8 1 HETATM 4895 N N2 . NAG C 3 . ? 23.274 127.633 -30.043 1.00 24.76 ? 701 NAG B N2 1 HETATM 4896 O O3 . NAG C 3 . ? 21.678 128.905 -28.124 1.00 27.23 ? 701 NAG B O3 1 HETATM 4897 O O4 . NAG C 3 . ? 22.718 131.215 -26.925 1.00 30.85 ? 701 NAG B O4 1 HETATM 4898 O O5 . NAG C 3 . ? 25.720 129.776 -28.293 1.00 22.00 ? 701 NAG B O5 1 HETATM 4899 O O6 . NAG C 3 . ? 25.994 131.197 -25.599 1.00 25.43 ? 701 NAG B O6 1 HETATM 4900 O O7 . NAG C 3 . ? 23.342 125.469 -29.323 1.00 18.52 ? 701 NAG B O7 1 HETATM 4901 C C1 . NAG D 3 . ? 22.127 131.446 -25.626 1.00 30.59 ? 702 NAG B C1 1 HETATM 4902 C C2 . NAG D 3 . ? 21.557 132.851 -25.437 1.00 31.95 ? 702 NAG B C2 1 HETATM 4903 C C3 . NAG D 3 . ? 21.067 133.081 -24.013 1.00 36.91 ? 702 NAG B C3 1 HETATM 4904 C C4 . NAG D 3 . ? 20.282 131.899 -23.450 1.00 39.50 ? 702 NAG B C4 1 HETATM 4905 C C5 . NAG D 3 . ? 20.972 130.560 -23.737 1.00 38.54 ? 702 NAG B C5 1 HETATM 4906 C C6 . NAG D 3 . ? 20.070 129.400 -23.337 1.00 35.55 ? 702 NAG B C6 1 HETATM 4907 C C7 . NAG D 3 . ? 22.750 134.489 -26.860 1.00 33.34 ? 702 NAG B C7 1 HETATM 4908 C C8 . NAG D 3 . ? 23.899 135.459 -26.894 1.00 27.02 ? 702 NAG B C8 1 HETATM 4909 N N2 . NAG D 3 . ? 22.588 133.838 -25.701 1.00 33.41 ? 702 NAG B N2 1 HETATM 4910 O O3 . NAG D 3 . ? 20.253 134.229 -24.010 1.00 38.43 ? 702 NAG B O3 1 HETATM 4911 O O4 . NAG D 3 . ? 20.118 132.075 -22.053 1.00 47.05 ? 702 NAG B O4 1 HETATM 4912 O O5 . NAG D 3 . ? 21.319 130.404 -25.108 1.00 36.19 ? 702 NAG B O5 1 HETATM 4913 O O6 . NAG D 3 . ? 20.676 128.207 -23.769 1.00 35.49 ? 702 NAG B O6 1 HETATM 4914 O O7 . NAG D 3 . ? 22.037 134.335 -27.860 1.00 30.62 ? 702 NAG B O7 1 HETATM 4915 C C1 . NAG E 3 . ? 38.227 132.417 -69.722 1.00 11.43 ? 703 NAG B C1 1 HETATM 4916 C C2 . NAG E 3 . ? 37.722 131.038 -70.166 1.00 13.07 ? 703 NAG B C2 1 HETATM 4917 C C3 . NAG E 3 . ? 36.423 131.106 -70.982 1.00 15.32 ? 703 NAG B C3 1 HETATM 4918 C C4 . NAG E 3 . ? 35.392 131.966 -70.250 1.00 18.05 ? 703 NAG B C4 1 HETATM 4919 C C5 . NAG E 3 . ? 36.038 133.333 -70.049 1.00 15.68 ? 703 NAG B C5 1 HETATM 4920 C C6 . NAG E 3 . ? 35.087 134.355 -69.441 1.00 14.56 ? 703 NAG B C6 1 HETATM 4921 C C7 . NAG E 3 . ? 39.115 129.057 -70.684 1.00 21.21 ? 703 NAG B C7 1 HETATM 4922 C C8 . NAG E 3 . ? 40.366 128.561 -71.350 1.00 9.46 ? 703 NAG B C8 1 HETATM 4923 N N2 . NAG E 3 . ? 38.781 130.335 -70.883 1.00 9.05 ? 703 NAG B N2 1 HETATM 4924 O O3 . NAG E 3 . ? 35.941 129.794 -71.151 1.00 22.16 ? 703 NAG B O3 1 HETATM 4925 O O4 . NAG E 3 . ? 34.083 132.017 -70.834 1.00 7.27 ? 703 NAG B O4 1 HETATM 4926 O O5 . NAG E 3 . ? 37.160 133.180 -69.193 1.00 12.04 ? 703 NAG B O5 1 HETATM 4927 O O6 . NAG E 3 . ? 34.576 133.835 -68.237 1.00 19.88 ? 703 NAG B O6 1 HETATM 4928 O O7 . NAG E 3 . ? 38.458 128.281 -70.000 1.00 29.13 ? 703 NAG B O7 1 HETATM 4929 C C1 . NAG F 3 . ? 39.341 130.757 -76.000 1.00 9.83 ? 704 NAG B C1 1 HETATM 4930 C C2 . NAG F 3 . ? 37.956 130.594 -75.337 1.00 20.39 ? 704 NAG B C2 1 HETATM 4931 C C3 . NAG F 3 . ? 37.878 129.371 -74.403 1.00 20.54 ? 704 NAG B C3 1 HETATM 4932 C C4 . NAG F 3 . ? 38.387 128.105 -75.084 1.00 25.33 ? 704 NAG B C4 1 HETATM 4933 C C5 . NAG F 3 . ? 39.778 128.404 -75.673 1.00 24.13 ? 704 NAG B C5 1 HETATM 4934 C C6 . NAG F 3 . ? 40.343 127.220 -76.443 1.00 22.18 ? 704 NAG B C6 1 HETATM 4935 C C7 . NAG F 3 . ? 36.525 132.575 -74.864 1.00 18.14 ? 704 NAG B C7 1 HETATM 4936 C C8 . NAG F 3 . ? 36.470 133.880 -74.128 1.00 10.70 ? 704 NAG B C8 1 HETATM 4937 N N2 . NAG F 3 . ? 37.581 131.796 -74.599 1.00 18.63 ? 704 NAG B N2 1 HETATM 4938 O O3 . NAG F 3 . ? 36.537 129.152 -74.032 1.00 19.46 ? 704 NAG B O3 1 HETATM 4939 O O4 . NAG F 3 . ? 38.309 126.969 -74.214 1.00 21.27 ? 704 NAG B O4 1 HETATM 4940 O O5 . NAG F 3 . ? 39.738 129.518 -76.565 1.00 11.55 ? 704 NAG B O5 1 HETATM 4941 O O6 . NAG F 3 . ? 39.543 127.004 -77.590 1.00 26.18 ? 704 NAG B O6 1 HETATM 4942 O O7 . NAG F 3 . ? 35.622 132.294 -75.654 1.00 27.34 ? 704 NAG B O7 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 CYS 1 61 61 CYS CYS B . n A 1 2 ASN 2 62 62 ASN ASN B . n A 1 3 TRP 3 63 63 TRP TRP B . n A 1 4 THR 4 64 64 THR THR B . n A 1 5 GLY 5 65 65 GLY GLY B . n A 1 6 VAL 6 66 66 VAL VAL B . n A 1 7 LYS 7 67 67 LYS LYS B . n A 1 8 CYS 8 68 68 CYS CYS B . n A 1 9 ASN 9 69 69 ASN ASN B . n A 1 10 ARG 10 70 70 ARG ARG B . n A 1 11 ARG 11 71 71 ARG ARG B . n A 1 12 GLY 12 72 72 GLY GLY B . n A 1 13 GLU 13 73 73 GLU GLU B . n A 1 14 VAL 14 74 74 VAL VAL B . n A 1 15 SER 15 75 75 SER SER B . n A 1 16 GLU 16 76 76 GLU GLU B . n A 1 17 ILE 17 77 77 ILE ILE B . n A 1 18 GLN 18 78 78 GLN GLN B . n A 1 19 LEU 19 79 79 LEU LEU B . n A 1 20 LYS 20 80 80 LYS LYS B . n A 1 21 GLU 21 81 81 GLU GLU B . n A 1 22 LYS 22 82 82 LYS LYS B . n A 1 23 GLN 23 83 83 GLN GLN B . n A 1 24 LEU 24 84 84 LEU LEU B . n A 1 25 GLN 25 85 85 GLN GLN B . n A 1 26 GLY 26 86 86 GLY GLY B . n A 1 27 SER 27 87 87 SER SER B . n A 1 28 LEU 28 88 88 LEU LEU B . n A 1 29 PRO 29 88 ? ? ? B A n A 1 30 VAL 30 88 ? ? ? B B n A 1 31 THR 31 88 ? ? ? B C n A 1 32 SER 32 88 ? ? ? B D n A 1 33 LEU 33 88 ? ? ? B E n A 1 34 ARG 34 88 ? ? ? B F n A 1 35 SER 35 88 ? ? ? B G n A 1 36 LEU 36 92 92 LEU LEU B . n A 1 37 LYS 37 93 93 LYS LYS B . n A 1 38 SER 38 94 94 SER SER B . n A 1 39 LEU 39 95 95 LEU LEU B . n A 1 40 THR 40 96 96 THR THR B . n A 1 41 SER 41 97 97 SER SER B . n A 1 42 LEU 42 98 98 LEU LEU B . n A 1 43 THR 43 99 99 THR THR B . n A 1 44 LEU 44 100 100 LEU LEU B . n A 1 45 SER 45 101 101 SER SER B . n A 1 46 SER 46 102 102 SER SER B . n A 1 47 LEU 47 103 103 LEU LEU B . n A 1 48 GLN 48 104 104 GLN GLN B . n A 1 49 LEU 49 105 105 LEU LEU B . n A 1 50 THR 50 106 106 THR THR B . n A 1 51 GLY 51 107 107 GLY GLY B . n A 1 52 VAL 52 108 108 VAL VAL B . n A 1 53 ILE 53 109 109 ILE ILE B . n A 1 54 PRO 54 110 110 PRO PRO B . n A 1 55 LYS 55 111 111 LYS LYS B . n A 1 56 GLU 56 112 112 GLU GLU B . n A 1 57 ILE 57 113 113 ILE ILE B . n A 1 58 GLY 58 114 114 GLY GLY B . n A 1 59 ASP 59 115 115 ASP ASP B . n A 1 60 PHE 60 116 116 PHE PHE B . n A 1 61 THR 61 117 117 THR THR B . n A 1 62 GLU 62 118 118 GLU GLU B . n A 1 63 LEU 63 119 119 LEU LEU B . n A 1 64 GLU 64 120 120 GLU GLU B . n A 1 65 LEU 65 121 121 LEU LEU B . n A 1 66 LEU 66 122 122 LEU LEU B . n A 1 67 ASP 67 123 123 ASP ASP B . n A 1 68 LEU 68 124 124 LEU LEU B . n A 1 69 SER 69 125 125 SER SER B . n A 1 70 ASP 70 126 126 ASP ASP B . n A 1 71 ASN 71 127 127 ASN ASN B . n A 1 72 SER 72 128 128 SER SER B . n A 1 73 LEU 73 129 129 LEU LEU B . n A 1 74 SER 74 130 130 SER SER B . n A 1 75 GLY 75 131 131 GLY GLY B . n A 1 76 ASP 76 132 132 ASP ASP B . n A 1 77 ILE 77 133 133 ILE ILE B . n A 1 78 PRO 78 134 134 PRO PRO B . n A 1 79 VAL 79 135 135 VAL VAL B . n A 1 80 GLU 80 136 136 GLU GLU B . n A 1 81 ILE 81 137 137 ILE ILE B . n A 1 82 PHE 82 138 138 PHE PHE B . n A 1 83 ARG 83 139 139 ARG ARG B . n A 1 84 LEU 84 140 140 LEU LEU B . n A 1 85 LYS 85 141 141 LYS LYS B . n A 1 86 LYS 86 142 142 LYS LYS B . n A 1 87 LEU 87 143 143 LEU LEU B . n A 1 88 LYS 88 144 144 LYS LYS B . n A 1 89 THR 89 145 145 THR THR B . n A 1 90 LEU 90 146 146 LEU LEU B . n A 1 91 SER 91 147 147 SER SER B . n A 1 92 LEU 92 148 148 LEU LEU B . n A 1 93 ASN 93 149 149 ASN ASN B . n A 1 94 THR 94 150 150 THR THR B . n A 1 95 ASN 95 151 151 ASN ASN B . n A 1 96 ASN 96 152 152 ASN ASN B . n A 1 97 LEU 97 153 153 LEU LEU B . n A 1 98 GLU 98 154 154 GLU GLU B . n A 1 99 GLY 99 155 155 GLY GLY B . n A 1 100 HIS 100 156 156 HIS HIS B . n A 1 101 ILE 101 157 157 ILE ILE B . n A 1 102 PRO 102 158 158 PRO PRO B . n A 1 103 MET 103 159 159 MET MET B . n A 1 104 GLU 104 160 160 GLU GLU B . n A 1 105 ILE 105 161 161 ILE ILE B . n A 1 106 GLY 106 162 162 GLY GLY B . n A 1 107 ASN 107 163 163 ASN ASN B . n A 1 108 LEU 108 164 164 LEU LEU B . n A 1 109 SER 109 165 165 SER SER B . n A 1 110 GLY 110 166 166 GLY GLY B . n A 1 111 LEU 111 167 167 LEU LEU B . n A 1 112 VAL 112 168 168 VAL VAL B . n A 1 113 GLU 113 169 169 GLU GLU B . n A 1 114 LEU 114 170 170 LEU LEU B . n A 1 115 MET 115 171 171 MET MET B . n A 1 116 LEU 116 172 172 LEU LEU B . n A 1 117 PHE 117 173 173 PHE PHE B . n A 1 118 ASP 118 174 174 ASP ASP B . n A 1 119 ASN 119 175 175 ASN ASN B . n A 1 120 LYS 120 176 176 LYS LYS B . n A 1 121 LEU 121 177 177 LEU LEU B . n A 1 122 SER 122 178 178 SER SER B . n A 1 123 GLY 123 179 179 GLY GLY B . n A 1 124 GLU 124 180 180 GLU GLU B . n A 1 125 ILE 125 181 181 ILE ILE B . n A 1 126 PRO 126 182 182 PRO PRO B . n A 1 127 ARG 127 183 183 ARG ARG B . n A 1 128 SER 128 184 184 SER SER B . n A 1 129 ILE 129 185 185 ILE ILE B . n A 1 130 GLY 130 186 186 GLY GLY B . n A 1 131 GLU 131 187 187 GLU GLU B . n A 1 132 LEU 132 188 188 LEU LEU B . n A 1 133 LYS 133 189 189 LYS LYS B . n A 1 134 ASN 134 190 190 ASN ASN B . n A 1 135 LEU 135 191 191 LEU LEU B . n A 1 136 GLN 136 192 192 GLN GLN B . n A 1 137 VAL 137 193 193 VAL VAL B . n A 1 138 LEU 138 194 194 LEU LEU B . n A 1 139 ARG 139 195 195 ARG ARG B . n A 1 140 ALA 140 196 196 ALA ALA B . n A 1 141 GLY 141 197 197 GLY GLY B . n A 1 142 GLY 142 198 198 GLY GLY B . n A 1 143 ASN 143 199 199 ASN ASN B . n A 1 144 LYS 144 200 200 LYS LYS B . n A 1 145 ASN 145 201 201 ASN ASN B . n A 1 146 LEU 146 202 202 LEU LEU B . n A 1 147 ARG 147 203 203 ARG ARG B . n A 1 148 GLY 148 204 204 GLY GLY B . n A 1 149 GLU 149 205 205 GLU GLU B . n A 1 150 LEU 150 206 206 LEU LEU B . n A 1 151 PRO 151 207 207 PRO PRO B . n A 1 152 TRP 152 208 208 TRP TRP B . n A 1 153 GLU 153 209 209 GLU GLU B . n A 1 154 ILE 154 210 210 ILE ILE B . n A 1 155 GLY 155 211 211 GLY GLY B . n A 1 156 ASN 156 212 212 ASN ASN B . n A 1 157 CYS 157 213 213 CYS CYS B . n A 1 158 GLU 158 214 214 GLU GLU B . n A 1 159 ASN 159 215 215 ASN ASN B . n A 1 160 LEU 160 216 216 LEU LEU B . n A 1 161 VAL 161 217 217 VAL VAL B . n A 1 162 MET 162 218 218 MET MET B . n A 1 163 LEU 163 219 219 LEU LEU B . n A 1 164 GLY 164 220 220 GLY GLY B . n A 1 165 LEU 165 221 221 LEU LEU B . n A 1 166 ALA 166 222 222 ALA ALA B . n A 1 167 GLU 167 223 223 GLU GLU B . n A 1 168 THR 168 224 224 THR THR B . n A 1 169 SER 169 225 225 SER SER B . n A 1 170 LEU 170 226 226 LEU LEU B . n A 1 171 SER 171 227 227 SER SER B . n A 1 172 GLY 172 228 228 GLY GLY B . n A 1 173 LYS 173 229 229 LYS LYS B . n A 1 174 LEU 174 230 230 LEU LEU B . n A 1 175 PRO 175 231 231 PRO PRO B . n A 1 176 ALA 176 232 232 ALA ALA B . n A 1 177 SER 177 233 233 SER SER B . n A 1 178 ILE 178 234 234 ILE ILE B . n A 1 179 GLY 179 235 235 GLY GLY B . n A 1 180 ASN 180 236 236 ASN ASN B . n A 1 181 LEU 181 237 237 LEU LEU B . n A 1 182 LYS 182 238 238 LYS LYS B . n A 1 183 ARG 183 239 239 ARG ARG B . n A 1 184 VAL 184 240 240 VAL VAL B . n A 1 185 GLN 185 241 241 GLN GLN B . n A 1 186 THR 186 242 242 THR THR B . n A 1 187 ILE 187 243 243 ILE ILE B . n A 1 188 ALA 188 244 244 ALA ALA B . n A 1 189 ILE 189 245 245 ILE ILE B . n A 1 190 TYR 190 246 246 TYR TYR B . n A 1 191 THR 191 247 247 THR THR B . n A 1 192 SER 192 248 248 SER SER B . n A 1 193 LEU 193 249 249 LEU LEU B . n A 1 194 LEU 194 250 250 LEU LEU B . n A 1 195 SER 195 251 251 SER SER B . n A 1 196 GLY 196 252 252 GLY GLY B . n A 1 197 PRO 197 253 253 PRO PRO B . n A 1 198 ILE 198 254 254 ILE ILE B . n A 1 199 PRO 199 255 255 PRO PRO B . n A 1 200 ASP 200 256 256 ASP ASP B . n A 1 201 GLU 201 257 257 GLU GLU B . n A 1 202 ILE 202 258 258 ILE ILE B . n A 1 203 GLY 203 259 259 GLY GLY B . n A 1 204 TYR 204 260 260 TYR TYR B . n A 1 205 CYS 205 261 261 CYS CYS B . n A 1 206 THR 206 262 262 THR THR B . n A 1 207 GLU 207 263 263 GLU GLU B . n A 1 208 LEU 208 264 264 LEU LEU B . n A 1 209 GLN 209 265 265 GLN GLN B . n A 1 210 ASN 210 266 266 ASN ASN B . n A 1 211 LEU 211 267 267 LEU LEU B . n A 1 212 TYR 212 268 268 TYR TYR B . n A 1 213 LEU 213 269 269 LEU LEU B . n A 1 214 TYR 214 270 270 TYR TYR B . n A 1 215 GLN 215 271 271 GLN GLN B . n A 1 216 ASN 216 272 272 ASN ASN B . n A 1 217 SER 217 273 273 SER SER B . n A 1 218 ILE 218 274 274 ILE ILE B . n A 1 219 SER 219 275 275 SER SER B . n A 1 220 GLY 220 276 276 GLY GLY B . n A 1 221 SER 221 277 277 SER SER B . n A 1 222 ILE 222 278 278 ILE ILE B . n A 1 223 PRO 223 279 279 PRO PRO B . n A 1 224 THR 224 280 280 THR THR B . n A 1 225 THR 225 281 281 THR THR B . n A 1 226 ILE 226 282 282 ILE ILE B . n A 1 227 GLY 227 283 283 GLY GLY B . n A 1 228 GLY 228 284 284 GLY GLY B . n A 1 229 LEU 229 285 285 LEU LEU B . n A 1 230 LYS 230 286 286 LYS LYS B . n A 1 231 LYS 231 287 287 LYS LYS B . n A 1 232 LEU 232 288 288 LEU LEU B . n A 1 233 GLN 233 289 289 GLN GLN B . n A 1 234 SER 234 290 290 SER SER B . n A 1 235 LEU 235 291 291 LEU LEU B . n A 1 236 LEU 236 292 292 LEU LEU B . n A 1 237 LEU 237 293 293 LEU LEU B . n A 1 238 TRP 238 294 294 TRP TRP B . n A 1 239 GLN 239 295 295 GLN GLN B . n A 1 240 ASN 240 296 296 ASN ASN B . n A 1 241 ASN 241 297 297 ASN ASN B . n A 1 242 LEU 242 298 298 LEU LEU B . n A 1 243 VAL 243 299 299 VAL VAL B . n A 1 244 GLY 244 300 300 GLY GLY B . n A 1 245 LYS 245 301 301 LYS LYS B . n A 1 246 ILE 246 302 302 ILE ILE B . n A 1 247 PRO 247 303 303 PRO PRO B . n A 1 248 THR 248 304 304 THR THR B . n A 1 249 GLU 249 305 305 GLU GLU B . n A 1 250 LEU 250 306 306 LEU LEU B . n A 1 251 GLY 251 307 307 GLY GLY B . n A 1 252 ASN 252 308 308 ASN ASN B . n A 1 253 CYS 253 309 309 CYS CYS B . n A 1 254 PRO 254 310 310 PRO PRO B . n A 1 255 GLU 255 311 311 GLU GLU B . n A 1 256 LEU 256 312 312 LEU LEU B . n A 1 257 TRP 257 313 313 TRP TRP B . n A 1 258 LEU 258 314 314 LEU LEU B . n A 1 259 ILE 259 315 315 ILE ILE B . n A 1 260 ASP 260 316 316 ASP ASP B . n A 1 261 PHE 261 317 317 PHE PHE B . n A 1 262 SER 262 318 318 SER SER B . n A 1 263 GLU 263 319 319 GLU GLU B . n A 1 264 ASN 264 320 320 ASN ASN B . n A 1 265 LEU 265 321 321 LEU LEU B . n A 1 266 LEU 266 322 322 LEU LEU B . n A 1 267 THR 267 323 323 THR THR B . n A 1 268 GLY 268 324 324 GLY GLY B . n A 1 269 THR 269 325 325 THR THR B . n A 1 270 ILE 270 326 326 ILE ILE B . n A 1 271 PRO 271 327 327 PRO PRO B . n A 1 272 ARG 272 328 328 ARG ARG B . n A 1 273 SER 273 329 329 SER SER B . n A 1 274 PHE 274 330 330 PHE PHE B . n A 1 275 GLY 275 331 331 GLY GLY B . n A 1 276 LYS 276 332 332 LYS LYS B . n A 1 277 LEU 277 333 333 LEU LEU B . n A 1 278 GLU 278 334 334 GLU GLU B . n A 1 279 ASN 279 335 335 ASN ASN B . n A 1 280 LEU 280 336 336 LEU LEU B . n A 1 281 GLN 281 337 337 GLN GLN B . n A 1 282 GLU 282 338 338 GLU GLU B . n A 1 283 LEU 283 339 339 LEU LEU B . n A 1 284 GLN 284 340 340 GLN GLN B . n A 1 285 LEU 285 341 341 LEU LEU B . n A 1 286 SER 286 342 342 SER SER B . n A 1 287 VAL 287 343 343 VAL VAL B . n A 1 288 ASN 288 344 344 ASN ASN B . n A 1 289 GLN 289 345 345 GLN GLN B . n A 1 290 ILE 290 346 346 ILE ILE B . n A 1 291 SER 291 347 347 SER SER B . n A 1 292 GLY 292 348 348 GLY GLY B . n A 1 293 THR 293 349 349 THR THR B . n A 1 294 ILE 294 350 350 ILE ILE B . n A 1 295 PRO 295 351 351 PRO PRO B . n A 1 296 GLU 296 352 352 GLU GLU B . n A 1 297 GLU 297 353 353 GLU GLU B . n A 1 298 LEU 298 354 354 LEU LEU B . n A 1 299 THR 299 355 355 THR THR B . n A 1 300 ASN 300 356 356 ASN ASN B . n A 1 301 CYS 301 357 357 CYS CYS B . n A 1 302 THR 302 358 358 THR THR B . n A 1 303 LYS 303 359 359 LYS LYS B . n A 1 304 LEU 304 360 360 LEU LEU B . n A 1 305 THR 305 361 361 THR THR B . n A 1 306 HIS 306 362 362 HIS HIS B . n A 1 307 LEU 307 363 363 LEU LEU B . n A 1 308 GLU 308 364 364 GLU GLU B . n A 1 309 ILE 309 365 365 ILE ILE B . n A 1 310 ASP 310 366 366 ASP ASP B . n A 1 311 ASN 311 367 367 ASN ASN B . n A 1 312 ASN 312 368 368 ASN ASN B . n A 1 313 LEU 313 369 369 LEU LEU B . n A 1 314 ILE 314 370 370 ILE ILE B . n A 1 315 THR 315 371 371 THR THR B . n A 1 316 GLY 316 372 372 GLY GLY B . n A 1 317 GLU 317 373 373 GLU GLU B . n A 1 318 ILE 318 374 374 ILE ILE B . n A 1 319 PRO 319 375 375 PRO PRO B . n A 1 320 SER 320 376 376 SER SER B . n A 1 321 LEU 321 377 377 LEU LEU B . n A 1 322 MET 322 378 378 MET MET B . n A 1 323 SER 323 379 379 SER SER B . n A 1 324 ASN 324 380 380 ASN ASN B . n A 1 325 LEU 325 381 381 LEU LEU B . n A 1 326 ARG 326 382 382 ARG ARG B . n A 1 327 SER 327 383 383 SER SER B . n A 1 328 LEU 328 384 384 LEU LEU B . n A 1 329 THR 329 385 385 THR THR B . n A 1 330 MET 330 386 386 MET MET B . n A 1 331 PHE 331 387 387 PHE PHE B . n A 1 332 PHE 332 388 388 PHE PHE B . n A 1 333 ALA 333 389 389 ALA ALA B . n A 1 334 TRP 334 390 390 TRP TRP B . n A 1 335 GLN 335 391 391 GLN GLN B . n A 1 336 ASN 336 392 392 ASN ASN B . n A 1 337 LYS 337 393 393 LYS LYS B . n A 1 338 LEU 338 394 394 LEU LEU B . n A 1 339 THR 339 395 395 THR THR B . n A 1 340 GLY 340 396 396 GLY GLY B . n A 1 341 ASN 341 397 397 ASN ASN B . n A 1 342 ILE 342 398 398 ILE ILE B . n A 1 343 PRO 343 399 399 PRO PRO B . n A 1 344 GLN 344 400 400 GLN GLN B . n A 1 345 SER 345 401 401 SER SER B . n A 1 346 LEU 346 402 402 LEU LEU B . n A 1 347 SER 347 403 403 SER SER B . n A 1 348 GLN 348 404 404 GLN GLN B . n A 1 349 CYS 349 405 405 CYS CYS B . n A 1 350 ARG 350 406 406 ARG ARG B . n A 1 351 GLU 351 407 407 GLU GLU B . n A 1 352 LEU 352 408 408 LEU LEU B . n A 1 353 GLN 353 409 409 GLN GLN B . n A 1 354 ALA 354 410 410 ALA ALA B . n A 1 355 ILE 355 411 411 ILE ILE B . n A 1 356 ASP 356 412 412 ASP ASP B . n A 1 357 LEU 357 413 413 LEU LEU B . n A 1 358 SER 358 414 414 SER SER B . n A 1 359 TYR 359 415 415 TYR TYR B . n A 1 360 ASN 360 416 416 ASN ASN B . n A 1 361 SER 361 417 417 SER SER B . n A 1 362 LEU 362 418 418 LEU LEU B . n A 1 363 SER 363 419 419 SER SER B . n A 1 364 GLY 364 420 420 GLY GLY B . n A 1 365 SER 365 421 421 SER SER B . n A 1 366 ILE 366 422 422 ILE ILE B . n A 1 367 PRO 367 423 423 PRO PRO B . n A 1 368 LYS 368 424 424 LYS LYS B . n A 1 369 GLU 369 425 425 GLU GLU B . n A 1 370 ILE 370 426 426 ILE ILE B . n A 1 371 PHE 371 427 427 PHE PHE B . n A 1 372 GLY 372 428 428 GLY GLY B . n A 1 373 LEU 373 429 429 LEU LEU B . n A 1 374 ARG 374 430 430 ARG ARG B . n A 1 375 ASN 375 431 431 ASN ASN B . n A 1 376 LEU 376 432 432 LEU LEU B . n A 1 377 THR 377 433 433 THR THR B . n A 1 378 LYS 378 434 434 LYS LYS B . n A 1 379 LEU 379 435 435 LEU LEU B . n A 1 380 LEU 380 436 436 LEU LEU B . n A 1 381 LEU 381 437 437 LEU LEU B . n A 1 382 LEU 382 438 438 LEU LEU B . n A 1 383 SER 383 439 439 SER SER B . n A 1 384 ASN 384 440 440 ASN ASN B . n A 1 385 ASP 385 441 441 ASP ASP B . n A 1 386 LEU 386 442 442 LEU LEU B . n A 1 387 SER 387 443 443 SER SER B . n A 1 388 GLY 388 444 444 GLY GLY B . n A 1 389 PHE 389 445 445 PHE PHE B . n A 1 390 ILE 390 446 446 ILE ILE B . n A 1 391 PRO 391 447 447 PRO PRO B . n A 1 392 PRO 392 448 448 PRO PRO B . n A 1 393 ASP 393 449 449 ASP ASP B . n A 1 394 ILE 394 450 450 ILE ILE B . n A 1 395 GLY 395 451 451 GLY GLY B . n A 1 396 ASN 396 452 452 ASN ASN B . n A 1 397 CYS 397 453 453 CYS CYS B . n A 1 398 THR 398 454 454 THR THR B . n A 1 399 ASN 399 455 455 ASN ASN B . n A 1 400 LEU 400 456 456 LEU LEU B . n A 1 401 TYR 401 457 457 TYR TYR B . n A 1 402 ARG 402 458 458 ARG ARG B . n A 1 403 LEU 403 459 459 LEU LEU B . n A 1 404 ARG 404 460 460 ARG ARG B . n A 1 405 LEU 405 461 461 LEU LEU B . n A 1 406 ASN 406 462 462 ASN ASN B . n A 1 407 GLY 407 463 463 GLY GLY B . n A 1 408 ASN 408 464 464 ASN ASN B . n A 1 409 ARG 409 465 465 ARG ARG B . n A 1 410 LEU 410 466 466 LEU LEU B . n A 1 411 ALA 411 467 467 ALA ALA B . n A 1 412 GLY 412 468 468 GLY GLY B . n A 1 413 SER 413 469 469 SER SER B . n A 1 414 ILE 414 470 470 ILE ILE B . n A 1 415 PRO 415 471 471 PRO PRO B . n A 1 416 SER 416 472 472 SER SER B . n A 1 417 GLU 417 473 473 GLU GLU B . n A 1 418 ILE 418 474 474 ILE ILE B . n A 1 419 GLY 419 475 475 GLY GLY B . n A 1 420 ASN 420 476 476 ASN ASN B . n A 1 421 LEU 421 477 477 LEU LEU B . n A 1 422 LYS 422 478 478 LYS LYS B . n A 1 423 ASN 423 479 479 ASN ASN B . n A 1 424 LEU 424 480 480 LEU LEU B . n A 1 425 ASN 425 481 481 ASN ASN B . n A 1 426 PHE 426 482 482 PHE PHE B . n A 1 427 VAL 427 483 483 VAL VAL B . n A 1 428 ASP 428 484 484 ASP ASP B . n A 1 429 ILE 429 485 485 ILE ILE B . n A 1 430 SER 430 486 486 SER SER B . n A 1 431 GLU 431 487 487 GLU GLU B . n A 1 432 ASN 432 488 488 ASN ASN B . n A 1 433 ARG 433 489 489 ARG ARG B . n A 1 434 LEU 434 490 490 LEU LEU B . n A 1 435 VAL 435 491 491 VAL VAL B . n A 1 436 GLY 436 492 492 GLY GLY B . n A 1 437 SER 437 493 493 SER SER B . n A 1 438 ILE 438 494 494 ILE ILE B . n A 1 439 PRO 439 495 495 PRO PRO B . n A 1 440 PRO 440 496 496 PRO PRO B . n A 1 441 ALA 441 497 497 ALA ALA B . n A 1 442 ILE 442 498 498 ILE ILE B . n A 1 443 SER 443 499 499 SER SER B . n A 1 444 GLY 444 500 500 GLY GLY B . n A 1 445 CYS 445 501 501 CYS CYS B . n A 1 446 GLU 446 502 502 GLU GLU B . n A 1 447 SER 447 503 503 SER SER B . n A 1 448 LEU 448 504 504 LEU LEU B . n A 1 449 GLU 449 505 505 GLU GLU B . n A 1 450 PHE 450 506 506 PHE PHE B . n A 1 451 LEU 451 507 507 LEU LEU B . n A 1 452 ASP 452 508 508 ASP ASP B . n A 1 453 LEU 453 509 509 LEU LEU B . n A 1 454 HIS 454 510 510 HIS HIS B . n A 1 455 THR 455 511 511 THR THR B . n A 1 456 ASN 456 512 512 ASN ASN B . n A 1 457 SER 457 513 513 SER SER B . n A 1 458 LEU 458 514 514 LEU LEU B . n A 1 459 SER 459 515 515 SER SER B . n A 1 460 GLY 460 516 516 GLY GLY B . n A 1 461 SER 461 517 517 SER SER B . n A 1 462 LEU 462 518 518 LEU LEU B . n A 1 463 LEU 463 519 519 LEU LEU B . n A 1 464 GLY 464 520 520 GLY GLY B . n A 1 465 THR 465 521 521 THR THR B . n A 1 466 THR 466 522 522 THR THR B . n A 1 467 LEU 467 523 523 LEU LEU B . n A 1 468 PRO 468 524 524 PRO PRO B . n A 1 469 LYS 469 525 525 LYS LYS B . n A 1 470 SER 470 526 526 SER SER B . n A 1 471 LEU 471 527 527 LEU LEU B . n A 1 472 LYS 472 528 528 LYS LYS B . n A 1 473 PHE 473 529 529 PHE PHE B . n A 1 474 ILE 474 530 530 ILE ILE B . n A 1 475 ASP 475 531 531 ASP ASP B . n A 1 476 PHE 476 532 532 PHE PHE B . n A 1 477 SER 477 533 533 SER SER B . n A 1 478 ASP 478 534 534 ASP ASP B . n A 1 479 ASN 479 535 535 ASN ASN B . n A 1 480 ALA 480 536 536 ALA ALA B . n A 1 481 LEU 481 537 537 LEU LEU B . n A 1 482 SER 482 538 538 SER SER B . n A 1 483 SER 483 539 539 SER SER B . n A 1 484 THR 484 540 540 THR THR B . n A 1 485 LEU 485 541 541 LEU LEU B . n A 1 486 PRO 486 542 542 PRO PRO B . n A 1 487 PRO 487 543 543 PRO PRO B . n A 1 488 GLY 488 544 544 GLY GLY B . n A 1 489 ILE 489 545 545 ILE ILE B . n A 1 490 GLY 490 546 546 GLY GLY B . n A 1 491 LEU 491 547 547 LEU LEU B . n A 1 492 LEU 492 548 548 LEU LEU B . n A 1 493 THR 493 549 549 THR THR B . n A 1 494 GLU 494 550 550 GLU GLU B . n A 1 495 LEU 495 551 551 LEU LEU B . n A 1 496 THR 496 552 552 THR THR B . n A 1 497 LYS 497 553 553 LYS LYS B . n A 1 498 LEU 498 554 554 LEU LEU B . n A 1 499 ASN 499 555 555 ASN ASN B . n A 1 500 LEU 500 556 556 LEU LEU B . n A 1 501 ALA 501 557 557 ALA ALA B . n A 1 502 LYS 502 558 558 LYS LYS B . n A 1 503 ASN 503 559 559 ASN ASN B . n A 1 504 ARG 504 560 560 ARG ARG B . n A 1 505 LEU 505 561 561 LEU LEU B . n A 1 506 SER 506 562 562 SER SER B . n A 1 507 GLY 507 563 563 GLY GLY B . n A 1 508 GLU 508 564 564 GLU GLU B . n A 1 509 ILE 509 565 565 ILE ILE B . n A 1 510 PRO 510 566 566 PRO PRO B . n A 1 511 ARG 511 567 567 ARG ARG B . n A 1 512 GLU 512 568 568 GLU GLU B . n A 1 513 ILE 513 569 569 ILE ILE B . n A 1 514 SER 514 570 570 SER SER B . n A 1 515 THR 515 571 571 THR THR B . n A 1 516 CYS 516 572 572 CYS CYS B . n A 1 517 ARG 517 573 573 ARG ARG B . n A 1 518 SER 518 574 574 SER SER B . n A 1 519 LEU 519 575 575 LEU LEU B . n A 1 520 GLN 520 576 576 GLN GLN B . n A 1 521 LEU 521 577 577 LEU LEU B . n A 1 522 LEU 522 578 578 LEU LEU B . n A 1 523 ASN 523 579 579 ASN ASN B . n A 1 524 LEU 524 580 580 LEU LEU B . n A 1 525 GLY 525 581 581 GLY GLY B . n A 1 526 GLU 526 582 582 GLU GLU B . n A 1 527 ASN 527 583 583 ASN ASN B . n A 1 528 ASP 528 584 584 ASP ASP B . n A 1 529 PHE 529 585 585 PHE PHE B . n A 1 530 SER 530 586 586 SER SER B . n A 1 531 GLY 531 587 587 GLY GLY B . n A 1 532 GLU 532 588 588 GLU GLU B . n A 1 533 ILE 533 589 589 ILE ILE B . n A 1 534 PRO 534 590 590 PRO PRO B . n A 1 535 ASP 535 591 591 ASP ASP B . n A 1 536 GLU 536 592 592 GLU GLU B . n A 1 537 LEU 537 593 593 LEU LEU B . n A 1 538 GLY 538 594 594 GLY GLY B . n A 1 539 GLN 539 595 595 GLN GLN B . n A 1 540 ILE 540 596 596 ILE ILE B . n A 1 541 PRO 541 597 597 PRO PRO B . n A 1 542 SER 542 598 598 SER SER B . n A 1 543 LEU 543 599 599 LEU LEU B . n A 1 544 ALA 544 600 600 ALA ALA B . n A 1 545 ILE 545 601 601 ILE ILE B . n A 1 546 SER 546 602 602 SER SER B . n A 1 547 LEU 547 603 603 LEU LEU B . n A 1 548 ASN 548 604 604 ASN ASN B . n A 1 549 LEU 549 605 605 LEU LEU B . n A 1 550 SER 550 606 606 SER SER B . n A 1 551 CYS 551 607 607 CYS CYS B . n A 1 552 ASN 552 608 608 ASN ASN B . n A 1 553 ARG 553 609 609 ARG ARG B . n A 1 554 PHE 554 610 610 PHE PHE B . n A 1 555 VAL 555 611 611 VAL VAL B . n A 1 556 GLY 556 612 612 GLY GLY B . n A 1 557 GLU 557 613 613 GLU GLU B . n A 1 558 ILE 558 614 614 ILE ILE B . n A 1 559 PRO 559 615 615 PRO PRO B . n A 1 560 SER 560 616 616 SER SER B . n A 1 561 ARG 561 617 617 ARG ARG B . n A 1 562 PHE 562 618 618 PHE PHE B . n A 1 563 SER 563 619 619 SER SER B . n A 1 564 ASP 564 620 620 ASP ASP B . n A 1 565 LEU 565 621 621 LEU LEU B . n A 1 566 LYS 566 622 622 LYS LYS B . n A 1 567 ASN 567 623 623 ASN ASN B . n A 1 568 LEU 568 624 624 LEU LEU B . n A 1 569 GLY 569 625 625 GLY GLY B . n A 1 570 VAL 570 626 626 VAL VAL B . n A 1 571 LEU 571 627 627 LEU LEU B . n A 1 572 ASP 572 628 628 ASP ASP B . n A 1 573 VAL 573 629 629 VAL VAL B . n A 1 574 SER 574 630 630 SER SER B . n A 1 575 HIS 575 631 631 HIS HIS B . n A 1 576 ASN 576 632 632 ASN ASN B . n A 1 577 GLN 577 633 633 GLN GLN B . n A 1 578 LEU 578 634 634 LEU LEU B . n A 1 579 THR 579 635 635 THR THR B . n A 1 580 GLY 580 636 636 GLY GLY B . n A 1 581 ASN 581 637 637 ASN ASN B . n A 1 582 LEU 582 638 638 LEU LEU B . n A 1 583 ASN 583 639 639 ASN ASN B . n A 1 584 VAL 584 640 640 VAL VAL B . n A 1 585 LEU 585 641 641 LEU LEU B . n A 1 586 THR 586 642 642 THR THR B . n A 1 587 ASP 587 643 643 ASP ASP B . n A 1 588 LEU 588 644 644 LEU LEU B . n A 1 589 GLN 589 645 645 GLN GLN B . n A 1 590 ASN 590 646 646 ASN ASN B . n A 1 591 LEU 591 647 647 LEU LEU B . n A 1 592 VAL 592 648 648 VAL VAL B . n A 1 593 SER 593 649 649 SER SER B . n A 1 594 LEU 594 650 650 LEU LEU B . n A 1 595 ASN 595 651 651 ASN ASN B . n A 1 596 ILE 596 652 652 ILE ILE B . n A 1 597 SER 597 653 653 SER SER B . n A 1 598 TYR 598 654 654 TYR TYR B . n A 1 599 ASN 599 655 655 ASN ASN B . n A 1 600 ASP 600 656 656 ASP ASP B . n A 1 601 PHE 601 657 657 PHE PHE B . n A 1 602 SER 602 658 658 SER SER B . n A 1 603 GLY 603 659 659 GLY GLY B . n A 1 604 ASP 604 660 660 ASP ASP B . n A 1 605 LEU 605 661 661 LEU LEU B . n A 1 606 PRO 606 662 662 PRO PRO B . n A 1 607 ASN 607 663 663 ASN ASN B . n A 1 608 THR 608 664 664 THR THR B . n A 1 609 PRO 609 665 665 PRO PRO B . n A 1 610 PHE 610 666 666 PHE PHE B . n A 1 611 PHE 611 667 667 PHE PHE B . n A 1 612 ARG 612 668 668 ARG ARG B . n A 1 613 ARG 613 669 669 ARG ARG B . n A 1 614 LEU 614 670 670 LEU LEU B . n A 1 615 PRO 615 671 671 PRO PRO B . n A 1 616 LEU 616 672 672 LEU LEU B . n A 1 617 SER 617 673 673 SER SER B . n A 1 618 ASP 618 674 674 ASP ASP B . n A 1 619 LEU 619 675 675 LEU LEU B . n A 1 620 ALA 620 676 676 ALA ALA B . n A 1 621 SER 621 677 677 SER SER B . n A 1 622 ASN 622 678 678 ASN ASN B . n A 1 623 ARG 623 679 679 ARG ARG B . n A 1 624 GLY 624 680 680 GLY GLY B . n A 1 625 LEU 625 681 681 LEU LEU B . n A 1 626 TYR 626 682 682 TYR TYR B . n A 1 627 ILE 627 683 683 ILE ILE B . n A 1 628 SER 628 684 684 SER SER B . n A 1 629 ASN 629 685 685 ASN ASN B . n A 1 630 ALA 630 686 686 ALA ALA B . n A 1 631 ILE 631 687 ? ? ? B . n A 1 632 SER 632 688 ? ? ? B . n A 1 633 THR 633 689 ? ? ? B . n B 2 1 ASP 1 44 44 ASP ASP A . n B 2 2 PTR 2 45 45 PTR PTR A . n B 2 3 TRP 3 46 46 TRP TRP A . n B 2 4 ARG 4 47 47 ARG ARG A . n B 2 5 ALA 5 48 48 ALA ALA A . n B 2 6 LYS 6 49 49 LYS LYS A . n B 2 7 HIS 7 50 50 HIS HIS A . n B 2 8 HIS 8 51 51 HIS HIS A . n B 2 9 PRO 9 52 52 PRO PRO A . n B 2 10 HZP 10 53 53 HZP HYP A . n B 2 11 LYS 11 54 54 LYS LYS A . n B 2 12 ASN 12 55 55 ASN ASN A . n B 2 13 ASN 13 56 56 ASN ASN A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 3 NAG 1 701 4521 NAG NAG B . D 3 NAG 2 702 4522 NAG NAG B . E 3 NAG 1 703 6041 NAG NAG B . F 3 NAG 1 704 6501 NAG NAG B . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 2920 ? 1 MORE 10 ? 1 'SSA (A^2)' 26610 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # _pdbx_audit_revision_history.ordinal 1 _pdbx_audit_revision_history.data_content_type 'Structure model' _pdbx_audit_revision_history.major_revision 1 _pdbx_audit_revision_history.minor_revision 0 _pdbx_audit_revision_history.revision_date 2017-03-22 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? . 1 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 2 ? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? 3.20 3 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 4 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? . 5 ? refinement ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? . 6 # _pdbx_validate_close_contact.id 1 _pdbx_validate_close_contact.PDB_model_num 1 _pdbx_validate_close_contact.auth_atom_id_1 O _pdbx_validate_close_contact.auth_asym_id_1 B _pdbx_validate_close_contact.auth_comp_id_1 GLY _pdbx_validate_close_contact.auth_seq_id_1 594 _pdbx_validate_close_contact.PDB_ins_code_1 ? _pdbx_validate_close_contact.label_alt_id_1 ? _pdbx_validate_close_contact.auth_atom_id_2 NH1 _pdbx_validate_close_contact.auth_asym_id_2 B _pdbx_validate_close_contact.auth_comp_id_2 ARG _pdbx_validate_close_contact.auth_seq_id_2 617 _pdbx_validate_close_contact.PDB_ins_code_2 ? _pdbx_validate_close_contact.label_alt_id_2 ? _pdbx_validate_close_contact.dist 2.05 # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 NE _pdbx_validate_rmsd_angle.auth_asym_id_1 B _pdbx_validate_rmsd_angle.auth_comp_id_1 ARG _pdbx_validate_rmsd_angle.auth_seq_id_1 617 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 CZ _pdbx_validate_rmsd_angle.auth_asym_id_2 B _pdbx_validate_rmsd_angle.auth_comp_id_2 ARG _pdbx_validate_rmsd_angle.auth_seq_id_2 617 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 NH1 _pdbx_validate_rmsd_angle.auth_asym_id_3 B _pdbx_validate_rmsd_angle.auth_comp_id_3 ARG _pdbx_validate_rmsd_angle.auth_seq_id_3 617 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 117.20 _pdbx_validate_rmsd_angle.angle_target_value 120.30 _pdbx_validate_rmsd_angle.angle_deviation -3.10 _pdbx_validate_rmsd_angle.angle_standard_deviation 0.50 _pdbx_validate_rmsd_angle.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 GLN B 83 ? ? 59.45 76.49 2 1 LEU B 84 ? ? -123.10 -169.77 3 1 THR B 96 ? ? -121.55 -57.93 4 1 SER B 248 ? ? -128.92 -165.68 5 1 GLN B 265 ? ? -121.56 -54.37 6 1 GLN B 295 ? ? 60.46 60.25 7 1 ASN B 296 ? ? -129.21 -163.20 8 1 ASN B 320 ? ? -128.74 -169.10 9 1 VAL B 343 ? ? 58.07 70.60 10 1 SER B 439 ? ? 53.25 71.19 11 1 SER B 539 ? ? 56.42 -146.17 12 1 ALA B 600 ? ? -135.76 -57.09 13 1 ASN B 608 ? ? -126.80 -169.99 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 B CYS 61 ? SG ? A CYS 1 SG 2 1 Y 1 B ASN 62 ? CG ? A ASN 2 CG 3 1 Y 1 B ASN 62 ? OD1 ? A ASN 2 OD1 4 1 Y 1 B ASN 62 ? ND2 ? A ASN 2 ND2 5 1 Y 1 B THR 64 ? OG1 ? A THR 4 OG1 6 1 Y 1 B THR 64 ? CG2 ? A THR 4 CG2 7 1 Y 1 B GLU 81 ? CG ? A GLU 21 CG 8 1 Y 1 B GLU 81 ? CD ? A GLU 21 CD 9 1 Y 1 B GLU 81 ? OE1 ? A GLU 21 OE1 10 1 Y 1 B GLU 81 ? OE2 ? A GLU 21 OE2 11 1 Y 1 B LYS 82 ? CG ? A LYS 22 CG 12 1 Y 1 B LYS 82 ? CD ? A LYS 22 CD 13 1 Y 1 B LYS 82 ? CE ? A LYS 22 CE 14 1 Y 1 B LYS 82 ? NZ ? A LYS 22 NZ 15 1 Y 1 B GLN 83 ? CG ? A GLN 23 CG 16 1 Y 1 B GLN 83 ? CD ? A GLN 23 CD 17 1 Y 1 B GLN 83 ? OE1 ? A GLN 23 OE1 18 1 Y 1 B GLN 83 ? NE2 ? A GLN 23 NE2 19 1 Y 1 B GLN 104 ? CG ? A GLN 48 CG 20 1 Y 1 B GLN 104 ? CD ? A GLN 48 CD 21 1 Y 1 B GLN 104 ? OE1 ? A GLN 48 OE1 22 1 Y 1 B GLN 104 ? NE2 ? A GLN 48 NE2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 B PRO 88 A A PRO 29 2 1 Y 1 B VAL 88 B A VAL 30 3 1 Y 1 B THR 88 C A THR 31 4 1 Y 1 B SER 88 D A SER 32 5 1 Y 1 B LEU 88 E A LEU 33 6 1 Y 1 B ARG 88 F A ARG 34 7 1 Y 1 B SER 88 G A SER 35 8 1 Y 1 B ILE 687 ? A ILE 631 9 1 Y 1 B SER 688 ? A SER 632 10 1 Y 1 B THR 689 ? A THR 633 # _pdbx_entity_nonpoly.entity_id 3 _pdbx_entity_nonpoly.name N-ACETYL-D-GLUCOSAMINE _pdbx_entity_nonpoly.comp_id NAG #