data_5HDH # _entry.id 5HDH # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5HDH WWPDB D_1000216864 # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5HDH _pdbx_database_status.recvd_initial_deposition_date 2016-01-05 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBJ _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Tanji, H.' 1 'Ohto, U.' 2 'Shimizu, T.' 3 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev Proc.Natl.Acad.Sci.USA _citation.journal_id_ASTM PNASA6 _citation.journal_id_CSD 0040 _citation.journal_id_ISSN 1091-6490 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 113 _citation.language ? _citation.page_first 3012 _citation.page_last 3017 _citation.title 'Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8' _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1073/pnas.1516000113 _citation.pdbx_database_id_PubMed 26929371 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Tanji, H.' 1 primary 'Ohto, U.' 2 primary 'Motoi, Y.' 3 primary 'Shibata, T.' 4 primary 'Miyake, K.' 5 primary 'Shimizu, T.' 6 # _cell.angle_alpha 90.00 _cell.angle_alpha_esd ? _cell.angle_beta 90.00 _cell.angle_beta_esd ? _cell.angle_gamma 120.00 _cell.angle_gamma_esd ? _cell.entry_id 5HDH _cell.details ? _cell.formula_units_Z ? _cell.length_a 171.520 _cell.length_a_esd ? _cell.length_b 171.520 _cell.length_b_esd ? _cell.length_c 301.333 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 18 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 5HDH _symmetry.cell_setting ? _symmetry.Int_Tables_number 155 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'H 3 2' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Toll-like receptor 8' 91407.523 1 ? ? 'UNP residues 27-827' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 12 ? ? ? ? 3 non-polymer man BETA-D-MANNOSE 180.156 2 ? ? ? ? 4 non-polymer man ALPHA-D-MANNOSE 180.156 3 ? ? ? ? 5 non-polymer syn 'SULFATE ION' 96.063 3 ? ? ? ? 6 non-polymer syn '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' 195.237 1 ? ? ? ? 7 water nat water 18.015 79 ? ? ? ? # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;EENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGN PGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKV CEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFP CVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSF NYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLS ENRISPLVKDTRQSYANSSSFQRHINQSNSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPD IACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNL KVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSN LLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDV T ; _entity_poly.pdbx_seq_one_letter_code_can ;EENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGN PGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKV CEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFP CVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSF NYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLS ENRISPLVKDTRQSYANSSSFQRHINQSNSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPD IACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNL KVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSN LLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDV T ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLU n 1 2 GLU n 1 3 ASN n 1 4 PHE n 1 5 SER n 1 6 ARG n 1 7 SER n 1 8 TYR n 1 9 PRO n 1 10 CYS n 1 11 ASP n 1 12 GLU n 1 13 LYS n 1 14 LYS n 1 15 GLN n 1 16 ASN n 1 17 ASP n 1 18 SER n 1 19 VAL n 1 20 ILE n 1 21 ALA n 1 22 GLU n 1 23 CYS n 1 24 SER n 1 25 ASN n 1 26 ARG n 1 27 ARG n 1 28 LEU n 1 29 GLN n 1 30 GLU n 1 31 VAL n 1 32 PRO n 1 33 GLN n 1 34 THR n 1 35 VAL n 1 36 GLY n 1 37 LYS n 1 38 TYR n 1 39 VAL n 1 40 THR n 1 41 GLU n 1 42 LEU n 1 43 ASP n 1 44 LEU n 1 45 SER n 1 46 ASP n 1 47 ASN n 1 48 PHE n 1 49 ILE n 1 50 THR n 1 51 HIS n 1 52 ILE n 1 53 THR n 1 54 ASN n 1 55 GLU n 1 56 SER n 1 57 PHE n 1 58 GLN n 1 59 GLY n 1 60 LEU n 1 61 GLN n 1 62 ASN n 1 63 LEU n 1 64 THR n 1 65 LYS n 1 66 ILE n 1 67 ASN n 1 68 LEU n 1 69 ASN n 1 70 HIS n 1 71 ASN n 1 72 PRO n 1 73 ASN n 1 74 VAL n 1 75 GLN n 1 76 HIS n 1 77 GLN n 1 78 ASN n 1 79 GLY n 1 80 ASN n 1 81 PRO n 1 82 GLY n 1 83 ILE n 1 84 GLN n 1 85 SER n 1 86 ASN n 1 87 GLY n 1 88 LEU n 1 89 ASN n 1 90 ILE n 1 91 THR n 1 92 ASP n 1 93 GLY n 1 94 ALA n 1 95 PHE n 1 96 LEU n 1 97 ASN n 1 98 LEU n 1 99 LYS n 1 100 ASN n 1 101 LEU n 1 102 ARG n 1 103 GLU n 1 104 LEU n 1 105 LEU n 1 106 LEU n 1 107 GLU n 1 108 ASP n 1 109 ASN n 1 110 GLN n 1 111 LEU n 1 112 PRO n 1 113 GLN n 1 114 ILE n 1 115 PRO n 1 116 SER n 1 117 GLY n 1 118 LEU n 1 119 PRO n 1 120 GLU n 1 121 SER n 1 122 LEU n 1 123 THR n 1 124 GLU n 1 125 LEU n 1 126 SER n 1 127 LEU n 1 128 ILE n 1 129 GLN n 1 130 ASN n 1 131 ASN n 1 132 ILE n 1 133 TYR n 1 134 ASN n 1 135 ILE n 1 136 THR n 1 137 LYS n 1 138 GLU n 1 139 GLY n 1 140 ILE n 1 141 SER n 1 142 ARG n 1 143 LEU n 1 144 ILE n 1 145 ASN n 1 146 LEU n 1 147 LYS n 1 148 ASN n 1 149 LEU n 1 150 TYR n 1 151 LEU n 1 152 ALA n 1 153 TRP n 1 154 ASN n 1 155 CYS n 1 156 TYR n 1 157 PHE n 1 158 ASN n 1 159 LYS n 1 160 VAL n 1 161 CYS n 1 162 GLU n 1 163 LYS n 1 164 THR n 1 165 ASN n 1 166 ILE n 1 167 GLU n 1 168 ASP n 1 169 GLY n 1 170 VAL n 1 171 PHE n 1 172 GLU n 1 173 THR n 1 174 LEU n 1 175 THR n 1 176 ASN n 1 177 LEU n 1 178 GLU n 1 179 LEU n 1 180 LEU n 1 181 SER n 1 182 LEU n 1 183 SER n 1 184 PHE n 1 185 ASN n 1 186 SER n 1 187 LEU n 1 188 SER n 1 189 HIS n 1 190 VAL n 1 191 PRO n 1 192 PRO n 1 193 LYS n 1 194 LEU n 1 195 PRO n 1 196 SER n 1 197 SER n 1 198 LEU n 1 199 ARG n 1 200 LYS n 1 201 LEU n 1 202 PHE n 1 203 LEU n 1 204 SER n 1 205 ASN n 1 206 THR n 1 207 GLN n 1 208 ILE n 1 209 LYS n 1 210 TYR n 1 211 ILE n 1 212 SER n 1 213 GLU n 1 214 GLU n 1 215 ASP n 1 216 PHE n 1 217 LYS n 1 218 GLY n 1 219 LEU n 1 220 ILE n 1 221 ASN n 1 222 LEU n 1 223 THR n 1 224 LEU n 1 225 LEU n 1 226 ASP n 1 227 LEU n 1 228 SER n 1 229 GLY n 1 230 ASN n 1 231 CYS n 1 232 PRO n 1 233 ARG n 1 234 CYS n 1 235 PHE n 1 236 ASN n 1 237 ALA n 1 238 PRO n 1 239 PHE n 1 240 PRO n 1 241 CYS n 1 242 VAL n 1 243 PRO n 1 244 CYS n 1 245 ASP n 1 246 GLY n 1 247 GLY n 1 248 ALA n 1 249 SER n 1 250 ILE n 1 251 ASN n 1 252 ILE n 1 253 ASP n 1 254 ARG n 1 255 PHE n 1 256 ALA n 1 257 PHE n 1 258 GLN n 1 259 ASN n 1 260 LEU n 1 261 THR n 1 262 GLN n 1 263 LEU n 1 264 ARG n 1 265 TYR n 1 266 LEU n 1 267 ASN n 1 268 LEU n 1 269 SER n 1 270 SER n 1 271 THR n 1 272 SER n 1 273 LEU n 1 274 ARG n 1 275 LYS n 1 276 ILE n 1 277 ASN n 1 278 ALA n 1 279 ALA n 1 280 TRP n 1 281 PHE n 1 282 LYS n 1 283 ASN n 1 284 MET n 1 285 PRO n 1 286 HIS n 1 287 LEU n 1 288 LYS n 1 289 VAL n 1 290 LEU n 1 291 ASP n 1 292 LEU n 1 293 GLU n 1 294 PHE n 1 295 ASN n 1 296 TYR n 1 297 LEU n 1 298 VAL n 1 299 GLY n 1 300 GLU n 1 301 ILE n 1 302 ALA n 1 303 SER n 1 304 GLY n 1 305 ALA n 1 306 PHE n 1 307 LEU n 1 308 THR n 1 309 MET n 1 310 LEU n 1 311 PRO n 1 312 ARG n 1 313 LEU n 1 314 GLU n 1 315 ILE n 1 316 LEU n 1 317 ASP n 1 318 LEU n 1 319 SER n 1 320 PHE n 1 321 ASN n 1 322 TYR n 1 323 ILE n 1 324 LYS n 1 325 GLY n 1 326 SER n 1 327 TYR n 1 328 PRO n 1 329 GLN n 1 330 HIS n 1 331 ILE n 1 332 ASN n 1 333 ILE n 1 334 SER n 1 335 ARG n 1 336 ASN n 1 337 PHE n 1 338 SER n 1 339 LYS n 1 340 LEU n 1 341 LEU n 1 342 SER n 1 343 LEU n 1 344 ARG n 1 345 ALA n 1 346 LEU n 1 347 HIS n 1 348 LEU n 1 349 ARG n 1 350 GLY n 1 351 TYR n 1 352 VAL n 1 353 PHE n 1 354 GLN n 1 355 GLU n 1 356 LEU n 1 357 ARG n 1 358 GLU n 1 359 ASP n 1 360 ASP n 1 361 PHE n 1 362 GLN n 1 363 PRO n 1 364 LEU n 1 365 MET n 1 366 GLN n 1 367 LEU n 1 368 PRO n 1 369 ASN n 1 370 LEU n 1 371 SER n 1 372 THR n 1 373 ILE n 1 374 ASN n 1 375 LEU n 1 376 GLY n 1 377 ILE n 1 378 ASN n 1 379 PHE n 1 380 ILE n 1 381 LYS n 1 382 GLN n 1 383 ILE n 1 384 ASP n 1 385 PHE n 1 386 LYS n 1 387 LEU n 1 388 PHE n 1 389 GLN n 1 390 ASN n 1 391 PHE n 1 392 SER n 1 393 ASN n 1 394 LEU n 1 395 GLU n 1 396 ILE n 1 397 ILE n 1 398 TYR n 1 399 LEU n 1 400 SER n 1 401 GLU n 1 402 ASN n 1 403 ARG n 1 404 ILE n 1 405 SER n 1 406 PRO n 1 407 LEU n 1 408 VAL n 1 409 LYS n 1 410 ASP n 1 411 THR n 1 412 ARG n 1 413 GLN n 1 414 SER n 1 415 TYR n 1 416 ALA n 1 417 ASN n 1 418 SER n 1 419 SER n 1 420 SER n 1 421 PHE n 1 422 GLN n 1 423 ARG n 1 424 HIS n 1 425 ILE n 1 426 ASN n 1 427 GLN n 1 428 SER n 1 429 ASN n 1 430 SER n 1 431 THR n 1 432 ASP n 1 433 PHE n 1 434 GLU n 1 435 PHE n 1 436 ASP n 1 437 PRO n 1 438 HIS n 1 439 SER n 1 440 ASN n 1 441 PHE n 1 442 TYR n 1 443 HIS n 1 444 PHE n 1 445 THR n 1 446 ARG n 1 447 PRO n 1 448 LEU n 1 449 ILE n 1 450 LYS n 1 451 PRO n 1 452 GLN n 1 453 CYS n 1 454 ALA n 1 455 ALA n 1 456 TYR n 1 457 GLY n 1 458 LYS n 1 459 ALA n 1 460 LEU n 1 461 ASP n 1 462 LEU n 1 463 SER n 1 464 LEU n 1 465 ASN n 1 466 SER n 1 467 ILE n 1 468 PHE n 1 469 PHE n 1 470 ILE n 1 471 GLY n 1 472 PRO n 1 473 ASN n 1 474 GLN n 1 475 PHE n 1 476 GLU n 1 477 ASN n 1 478 LEU n 1 479 PRO n 1 480 ASP n 1 481 ILE n 1 482 ALA n 1 483 CYS n 1 484 LEU n 1 485 ASN n 1 486 LEU n 1 487 SER n 1 488 ALA n 1 489 ASN n 1 490 SER n 1 491 ASN n 1 492 ALA n 1 493 GLN n 1 494 VAL n 1 495 LEU n 1 496 SER n 1 497 GLY n 1 498 THR n 1 499 GLU n 1 500 PHE n 1 501 SER n 1 502 ALA n 1 503 ILE n 1 504 PRO n 1 505 HIS n 1 506 VAL n 1 507 LYS n 1 508 TYR n 1 509 LEU n 1 510 ASP n 1 511 LEU n 1 512 THR n 1 513 ASN n 1 514 ASN n 1 515 ARG n 1 516 LEU n 1 517 ASP n 1 518 PHE n 1 519 ASP n 1 520 ASN n 1 521 ALA n 1 522 SER n 1 523 ALA n 1 524 LEU n 1 525 THR n 1 526 GLU n 1 527 LEU n 1 528 SER n 1 529 ASP n 1 530 LEU n 1 531 GLU n 1 532 VAL n 1 533 LEU n 1 534 ASP n 1 535 LEU n 1 536 SER n 1 537 TYR n 1 538 ASN n 1 539 SER n 1 540 HIS n 1 541 TYR n 1 542 PHE n 1 543 ARG n 1 544 ILE n 1 545 ALA n 1 546 GLY n 1 547 VAL n 1 548 THR n 1 549 HIS n 1 550 HIS n 1 551 LEU n 1 552 GLU n 1 553 PHE n 1 554 ILE n 1 555 GLN n 1 556 ASN n 1 557 PHE n 1 558 THR n 1 559 ASN n 1 560 LEU n 1 561 LYS n 1 562 VAL n 1 563 LEU n 1 564 ASN n 1 565 LEU n 1 566 SER n 1 567 HIS n 1 568 ASN n 1 569 ASN n 1 570 ILE n 1 571 TYR n 1 572 THR n 1 573 LEU n 1 574 THR n 1 575 ASP n 1 576 LYS n 1 577 TYR n 1 578 ASN n 1 579 LEU n 1 580 GLU n 1 581 SER n 1 582 LYS n 1 583 SER n 1 584 LEU n 1 585 VAL n 1 586 GLU n 1 587 LEU n 1 588 VAL n 1 589 PHE n 1 590 SER n 1 591 GLY n 1 592 ASN n 1 593 ARG n 1 594 LEU n 1 595 ASP n 1 596 ILE n 1 597 LEU n 1 598 TRP n 1 599 ASN n 1 600 ASP n 1 601 ASP n 1 602 ASP n 1 603 ASN n 1 604 ARG n 1 605 TYR n 1 606 ILE n 1 607 SER n 1 608 ILE n 1 609 PHE n 1 610 LYS n 1 611 GLY n 1 612 LEU n 1 613 LYS n 1 614 ASN n 1 615 LEU n 1 616 THR n 1 617 ARG n 1 618 LEU n 1 619 ASP n 1 620 LEU n 1 621 SER n 1 622 LEU n 1 623 ASN n 1 624 ARG n 1 625 LEU n 1 626 LYS n 1 627 HIS n 1 628 ILE n 1 629 PRO n 1 630 ASN n 1 631 GLU n 1 632 ALA n 1 633 PHE n 1 634 LEU n 1 635 ASN n 1 636 LEU n 1 637 PRO n 1 638 ALA n 1 639 SER n 1 640 LEU n 1 641 THR n 1 642 GLU n 1 643 LEU n 1 644 HIS n 1 645 ILE n 1 646 ASN n 1 647 ASP n 1 648 ASN n 1 649 MET n 1 650 LEU n 1 651 LYS n 1 652 PHE n 1 653 PHE n 1 654 ASN n 1 655 TRP n 1 656 THR n 1 657 LEU n 1 658 LEU n 1 659 GLN n 1 660 GLN n 1 661 PHE n 1 662 PRO n 1 663 ARG n 1 664 LEU n 1 665 GLU n 1 666 LEU n 1 667 LEU n 1 668 ASP n 1 669 LEU n 1 670 ARG n 1 671 GLY n 1 672 ASN n 1 673 LYS n 1 674 LEU n 1 675 LEU n 1 676 PHE n 1 677 LEU n 1 678 THR n 1 679 ASP n 1 680 SER n 1 681 LEU n 1 682 SER n 1 683 ASP n 1 684 PHE n 1 685 THR n 1 686 SER n 1 687 SER n 1 688 LEU n 1 689 ARG n 1 690 THR n 1 691 LEU n 1 692 LEU n 1 693 LEU n 1 694 SER n 1 695 HIS n 1 696 ASN n 1 697 ARG n 1 698 ILE n 1 699 SER n 1 700 HIS n 1 701 LEU n 1 702 PRO n 1 703 SER n 1 704 GLY n 1 705 PHE n 1 706 LEU n 1 707 SER n 1 708 GLU n 1 709 VAL n 1 710 SER n 1 711 SER n 1 712 LEU n 1 713 LYS n 1 714 HIS n 1 715 LEU n 1 716 ASP n 1 717 LEU n 1 718 SER n 1 719 SER n 1 720 ASN n 1 721 LEU n 1 722 LEU n 1 723 LYS n 1 724 THR n 1 725 ILE n 1 726 ASN n 1 727 LYS n 1 728 SER n 1 729 ALA n 1 730 LEU n 1 731 GLU n 1 732 THR n 1 733 LYS n 1 734 THR n 1 735 THR n 1 736 THR n 1 737 LYS n 1 738 LEU n 1 739 SER n 1 740 MET n 1 741 LEU n 1 742 GLU n 1 743 LEU n 1 744 HIS n 1 745 GLY n 1 746 ASN n 1 747 PRO n 1 748 PHE n 1 749 GLU n 1 750 CYS n 1 751 THR n 1 752 CYS n 1 753 ASP n 1 754 ILE n 1 755 GLY n 1 756 ASP n 1 757 PHE n 1 758 ARG n 1 759 ARG n 1 760 TRP n 1 761 MET n 1 762 ASP n 1 763 GLU n 1 764 HIS n 1 765 LEU n 1 766 ASN n 1 767 VAL n 1 768 LYS n 1 769 ILE n 1 770 PRO n 1 771 ARG n 1 772 LEU n 1 773 VAL n 1 774 ASP n 1 775 VAL n 1 776 ILE n 1 777 CYS n 1 778 ALA n 1 779 SER n 1 780 PRO n 1 781 GLY n 1 782 ASP n 1 783 GLN n 1 784 ARG n 1 785 GLY n 1 786 LYS n 1 787 SER n 1 788 ILE n 1 789 VAL n 1 790 SER n 1 791 LEU n 1 792 GLU n 1 793 LEU n 1 794 THR n 1 795 THR n 1 796 CYS n 1 797 VAL n 1 798 SER n 1 799 ASP n 1 800 VAL n 1 801 THR n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 801 _entity_src_gen.gene_src_common_name Human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'TLR8, UNQ249/PRO286' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name Drosophila _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7215 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code TLR8_HUMAN _struct_ref.pdbx_db_accession Q9NR97 _struct_ref.pdbx_db_isoform ? _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;EENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGN PGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKV CEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFP CVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSF NYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLS ENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPD IACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNL KVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSN LLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDV T ; _struct_ref.pdbx_align_begin 27 # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 5HDH _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 801 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession Q9NR97 _struct_ref_seq.db_align_beg 27 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 827 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 27 _struct_ref_seq.pdbx_auth_seq_align_end 827 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 5HDH ASN A 426 ? UNP Q9NR97 ARG 452 'engineered mutation' 452 1 1 5HDH GLN A 427 ? UNP Q9NR97 LYS 453 'engineered mutation' 453 2 1 5HDH SER A 428 ? UNP Q9NR97 ARG 454 'engineered mutation' 454 3 1 5HDH ASN A 429 ? UNP Q9NR97 ARG 455 'engineered mutation' 455 4 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MES non-polymer . '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' ? 'C6 H13 N O4 S' 195.237 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5HDH _exptl.crystals_number ? _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 4.67 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 73.64 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details 'ammonium sulfate, sodium acetate, glycerol' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'ADSC QUANTUM 270' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2013-06-01 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.0000 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'PHOTON FACTORY BEAMLINE AR-NE3A' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 1.0000 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline AR-NE3A _diffrn_source.pdbx_synchrotron_site 'Photon Factory' # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5HDH _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 2.60 _reflns.d_resolution_low 45.02 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 49967 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 100.0 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 19.5 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 17.3 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _refine.aniso_B[1][1] 0.01 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] -0.00 _refine.aniso_B[2][2] 0.01 _refine.aniso_B[2][3] -0.00 _refine.aniso_B[3][3] -0.02 _refine.B_iso_max ? _refine.B_iso_mean 80.137 _refine.B_iso_min ? _refine.correlation_coeff_Fo_to_Fc 0.950 _refine.correlation_coeff_Fo_to_Fc_free 0.936 _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 5HDH _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 2.60 _refine.ls_d_res_low 45.02 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 49947 _refine.ls_number_reflns_R_free 2610 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 99.96 _refine.ls_percent_reflns_R_free 5.0 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.20756 _refine.ls_R_factor_R_free 0.23944 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.20589 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details MASK _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_starting_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R 0.278 _refine.pdbx_overall_ESU_R_Free 0.226 _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B 8.721 _refine.overall_SU_ML 0.183 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id 1 _refine_hist.pdbx_number_atoms_protein 6042 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 250 _refine_hist.number_atoms_solvent 79 _refine_hist.number_atoms_total 6371 _refine_hist.d_res_high 2.60 _refine_hist.d_res_low 45.02 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.criterion _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.rejects _refine_ls_restr.type _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' ? 0.012 0.019 6435 ? r_bond_refined_d ? ? 'X-RAY DIFFRACTION' ? 0.002 0.020 6119 ? r_bond_other_d ? ? 'X-RAY DIFFRACTION' ? 1.770 2.012 8744 ? r_angle_refined_deg ? ? 'X-RAY DIFFRACTION' ? 0.832 3.000 14019 ? r_angle_other_deg ? ? 'X-RAY DIFFRACTION' ? 1.957 5.000 745 ? r_dihedral_angle_1_deg ? ? 'X-RAY DIFFRACTION' ? 27.044 24.883 299 ? r_dihedral_angle_2_deg ? ? 'X-RAY DIFFRACTION' ? 10.858 15.000 1094 ? r_dihedral_angle_3_deg ? ? 'X-RAY DIFFRACTION' ? 9.719 15.000 31 ? r_dihedral_angle_4_deg ? ? 'X-RAY DIFFRACTION' ? 0.123 0.200 1045 ? r_chiral_restr ? ? 'X-RAY DIFFRACTION' ? 0.013 0.020 7033 ? r_gen_planes_refined ? ? 'X-RAY DIFFRACTION' ? 0.002 0.020 1462 ? r_gen_planes_other ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_nbd_refined ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_nbd_other ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_nbtor_refined ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_nbtor_other ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_xyhbond_nbd_refined ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_xyhbond_nbd_other ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_metal_ion_refined ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_metal_ion_other ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_symmetry_vdw_refined ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_symmetry_vdw_other ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_symmetry_hbond_refined ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_symmetry_hbond_other ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_symmetry_metal_ion_refined ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_symmetry_metal_ion_other ? ? 'X-RAY DIFFRACTION' ? 7.607 7.701 2998 ? r_mcbond_it ? ? 'X-RAY DIFFRACTION' ? 7.602 7.700 2997 ? r_mcbond_other ? ? 'X-RAY DIFFRACTION' ? 10.530 11.517 3737 ? r_mcangle_it ? ? 'X-RAY DIFFRACTION' ? 10.529 11.520 3738 ? r_mcangle_other ? ? 'X-RAY DIFFRACTION' ? 8.460 8.386 3437 ? r_scbond_it ? ? 'X-RAY DIFFRACTION' ? 8.458 8.386 3437 ? r_scbond_other ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_scangle_it ? ? 'X-RAY DIFFRACTION' ? 12.428 12.312 5008 ? r_scangle_other ? ? 'X-RAY DIFFRACTION' ? 16.047 63.321 7338 ? r_long_range_B_refined ? ? 'X-RAY DIFFRACTION' ? 16.051 63.322 7332 ? r_long_range_B_other ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_rigid_bond_restr ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_sphericity_free ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? r_sphericity_bonded ? ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.d_res_high 2.600 _refine_ls_shell.d_res_low 2.668 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.number_reflns_R_free 191 _refine_ls_shell.number_reflns_R_work 3676 _refine_ls_shell.percent_reflns_obs 100.00 _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_obs ? _refine_ls_shell.R_factor_R_free 0.346 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.R_factor_R_work 0.323 _refine_ls_shell.redundancy_reflns_all ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.wR_factor_all ? _refine_ls_shell.wR_factor_obs ? _refine_ls_shell.wR_factor_R_free ? _refine_ls_shell.wR_factor_R_work ? _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.pdbx_phase_error ? _refine_ls_shell.pdbx_fsc_work ? _refine_ls_shell.pdbx_fsc_free ? # _struct.entry_id 5HDH _struct.title 'Crystal structure of human TLR8 with an uncleaved Z-loop' _struct.pdbx_descriptor 'Toll-like receptor 8' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5HDH _struct_keywords.text 'IMMUNE SYSTEM, TLR8, innate immunity, proteolytic cleavage' _struct_keywords.pdbx_keywords 'IMMUNE SYSTEM' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 2 ? E N N 3 ? F N N 4 ? G N N 2 ? H N N 2 ? I N N 2 ? J N N 2 ? K N N 2 ? L N N 2 ? M N N 2 ? N N N 2 ? O N N 3 ? P N N 4 ? Q N N 4 ? R N N 2 ? S N N 5 ? T N N 5 ? U N N 5 ? V N N 6 ? W N N 7 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 CYS A 244 ? ALA A 248 ? CYS A 270 ALA A 274 5 ? 5 HELX_P HELX_P2 AA2 ASN A 277 ? LYS A 282 ? ASN A 303 LYS A 308 5 ? 6 HELX_P HELX_P3 AA3 LEU A 297 ? GLY A 304 ? LEU A 323 GLY A 330 1 ? 8 HELX_P HELX_P4 AA4 ALA A 305 ? LEU A 310 ? ALA A 331 LEU A 336 5 ? 6 HELX_P HELX_P5 AA5 SER A 334 ? LEU A 340 ? SER A 360 LEU A 366 5 ? 7 HELX_P HELX_P6 AA6 ARG A 357 ? MET A 365 ? ARG A 383 MET A 391 5 ? 9 HELX_P HELX_P7 AA7 PHE A 385 ? PHE A 391 ? PHE A 411 PHE A 417 5 ? 7 HELX_P HELX_P8 AA8 LYS A 450 ? ALA A 455 ? LYS A 476 ALA A 481 1 ? 6 HELX_P HELX_P9 AA9 SER A 539 ? ILE A 544 ? SER A 565 ILE A 570 1 ? 6 HELX_P HELX_P10 AB1 LEU A 551 ? PHE A 557 ? LEU A 577 PHE A 583 5 ? 7 HELX_P HELX_P11 AB2 ARG A 593 ? ASP A 600 ? ARG A 619 ASP A 626 1 ? 8 HELX_P HELX_P12 AB3 PRO A 629 ? ASN A 635 ? PRO A 655 ASN A 661 1 ? 7 HELX_P HELX_P13 AB4 ASN A 654 ? PHE A 661 ? ASN A 680 PHE A 687 5 ? 8 HELX_P HELX_P14 AB5 SER A 680 ? PHE A 684 ? SER A 706 PHE A 710 5 ? 5 HELX_P HELX_P15 AB6 THR A 751 ? ASP A 753 ? THR A 777 ASP A 779 5 ? 3 HELX_P HELX_P16 AB7 ILE A 754 ? HIS A 764 ? ILE A 780 HIS A 790 1 ? 11 HELX_P HELX_P17 AB8 GLU A 792 ? VAL A 797 ? GLU A 818 VAL A 823 5 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 10 SG ? ? ? 1_555 A CYS 23 SG ? ? A CYS 36 A CYS 49 1_555 ? ? ? ? ? ? ? 2.033 ? disulf2 disulf ? ? A CYS 155 SG ? ? ? 1_555 A CYS 161 SG ? ? A CYS 181 A CYS 187 1_555 ? ? ? ? ? ? ? 2.030 ? disulf3 disulf ? ? A CYS 231 SG ? ? ? 1_555 A CYS 244 SG ? ? A CYS 257 A CYS 270 1_555 ? ? ? ? ? ? ? 2.078 ? disulf4 disulf ? ? A CYS 234 SG ? ? ? 1_555 A CYS 241 SG ? ? A CYS 260 A CYS 267 1_555 ? ? ? ? ? ? ? 2.052 ? disulf5 disulf ? ? A CYS 453 SG ? ? ? 1_555 A CYS 483 SG ? ? A CYS 479 A CYS 509 1_555 ? ? ? ? ? ? ? 2.031 ? disulf6 disulf ? ? A CYS 750 SG ? ? ? 1_555 A CYS 777 SG ? ? A CYS 776 A CYS 803 1_555 ? ? ? ? ? ? ? 2.035 ? disulf7 disulf ? ? A CYS 752 SG ? ? ? 1_555 A CYS 796 SG ? ? A CYS 778 A CYS 822 1_555 ? ? ? ? ? ? ? 2.040 ? covale1 covale one ? A ASN 259 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 285 A NAG 901 1_555 ? ? ? ? ? ? ? 1.300 ? covale2 covale one ? A ASN 267 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 293 A NAG 902 1_555 ? ? ? ? ? ? ? 1.446 ? covale3 covale one ? A ASN 369 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 395 A NAG 906 1_555 ? ? ? ? ? ? ? 1.446 ? covale4 covale one ? A ASN 390 ND2 ? ? ? 1_555 H NAG . C1 ? ? A ASN 416 A NAG 907 1_555 ? ? ? ? ? ? ? 1.438 ? covale5 covale one ? A ASN 485 ND2 ? ? ? 1_555 I NAG . C1 ? ? A ASN 511 A NAG 908 1_555 ? ? ? ? ? ? ? 1.429 ? covale6 covale one ? A ASN 520 ND2 ? ? ? 1_555 K NAG . C1 ? ? A ASN 546 A NAG 910 1_555 ? ? ? ? ? ? ? 1.428 ? covale7 covale one ? A ASN 556 ND2 ? ? ? 1_555 L NAG . C1 ? ? A ASN 582 A NAG 911 1_555 ? ? ? ? ? ? ? 1.434 ? covale8 covale one ? A ASN 564 ND2 ? ? ? 1_555 M NAG . C1 ? ? A ASN 590 A NAG 912 1_555 ? ? ? ? ? ? ? 1.448 ? covale9 covale one ? A ASN 614 ND2 ? ? ? 1_555 R NAG . C1 ? ? A ASN 640 A NAG 917 1_555 ? ? ? ? ? ? ? 1.430 ? covale10 covale both ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? A NAG 902 A NAG 903 1_555 ? ? ? ? ? ? ? 1.431 ? covale11 covale both ? D NAG . O4 ? ? ? 1_555 E BMA . C1 ? ? A NAG 903 A BMA 904 1_555 ? ? ? ? ? ? ? 1.431 ? covale12 covale one ? E BMA . O6 ? ? ? 1_555 F MAN . C1 ? ? A BMA 904 A MAN 905 1_555 ? ? ? ? ? ? ? 1.444 ? covale13 covale both ? I NAG . O4 ? ? ? 1_555 J NAG . C1 ? ? A NAG 908 A NAG 909 1_555 ? ? ? ? ? ? ? 1.439 ? covale14 covale both ? M NAG . O4 ? ? ? 1_555 N NAG . C1 ? ? A NAG 912 A NAG 913 1_555 ? ? ? ? ? ? ? 1.442 ? covale15 covale both ? N NAG . O4 ? ? ? 1_555 O BMA . C1 ? ? A NAG 913 A BMA 914 1_555 ? ? ? ? ? ? ? 1.449 ? covale16 covale one ? O BMA . O3 ? ? ? 1_555 Q MAN . C1 ? ? A BMA 914 A MAN 916 1_555 ? ? ? ? ? ? ? 1.443 ? covale17 covale one ? O BMA . O6 ? ? ? 1_555 P MAN . C1 ? ? A BMA 914 A MAN 915 1_555 ? ? ? ? ? ? ? 1.464 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 TYR 8 A . ? TYR 34 A PRO 9 A ? PRO 35 A 1 -1.27 2 GLN 15 A . ? GLN 41 A ASN 16 A ? ASN 42 A 1 -2.96 3 ASN 71 A . ? ASN 97 A PRO 72 A ? PRO 98 A 1 0.09 4 PHE 157 A . ? PHE 183 A ASN 158 A ? ASN 184 A 1 0.25 5 LYS 159 A . ? LYS 185 A VAL 160 A ? VAL 186 A 1 -0.33 6 PHE 239 A . ? PHE 265 A PRO 240 A ? PRO 266 A 1 2.89 7 PRO 437 A . ? PRO 463 A HIS 438 A ? HIS 464 A 1 -1.30 8 GLY 704 A . ? GLY 730 A PHE 705 A ? PHE 731 A 1 0.99 9 PHE 705 A . ? PHE 731 A LEU 706 A ? LEU 732 A 1 -0.29 10 SER 779 A . ? SER 805 A PRO 780 A ? PRO 806 A 1 0.48 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 28 ? AA2 ? 2 ? AA3 ? 2 ? AA4 ? 2 ? AA5 ? 2 ? AA6 ? 2 ? AA7 ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? parallel AA1 3 4 ? parallel AA1 4 5 ? parallel AA1 5 6 ? parallel AA1 6 7 ? parallel AA1 7 8 ? parallel AA1 8 9 ? parallel AA1 9 10 ? parallel AA1 10 11 ? parallel AA1 11 12 ? parallel AA1 12 13 ? parallel AA1 13 14 ? parallel AA1 14 15 ? parallel AA1 15 16 ? parallel AA1 16 17 ? parallel AA1 17 18 ? parallel AA1 18 19 ? parallel AA1 19 20 ? parallel AA1 20 21 ? parallel AA1 21 22 ? parallel AA1 22 23 ? parallel AA1 23 24 ? parallel AA1 24 25 ? parallel AA1 25 26 ? parallel AA1 26 27 ? parallel AA1 27 28 ? parallel AA2 1 2 ? parallel AA3 1 2 ? parallel AA4 1 2 ? parallel AA5 1 2 ? parallel AA6 1 2 ? parallel AA7 1 2 ? parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 ASP A 11 ? LYS A 14 ? ASP A 37 LYS A 40 AA1 2 VAL A 19 ? GLU A 22 ? VAL A 45 GLU A 48 AA1 3 GLU A 41 ? ASP A 43 ? GLU A 67 ASP A 69 AA1 4 LYS A 65 ? ASN A 67 ? LYS A 91 ASN A 93 AA1 5 GLU A 103 ? LEU A 105 ? GLU A 129 LEU A 131 AA1 6 GLU A 124 ? SER A 126 ? GLU A 150 SER A 152 AA1 7 ASN A 148 ? TYR A 150 ? ASN A 174 TYR A 176 AA1 8 LEU A 179 ? SER A 181 ? LEU A 205 SER A 207 AA1 9 LYS A 200 ? PHE A 202 ? LYS A 226 PHE A 228 AA1 10 LEU A 224 ? ASP A 226 ? LEU A 250 ASP A 252 AA1 11 TYR A 265 ? ASN A 267 ? TYR A 291 ASN A 293 AA1 12 VAL A 289 ? ASP A 291 ? VAL A 315 ASP A 317 AA1 13 ILE A 315 ? ASP A 317 ? ILE A 341 ASP A 343 AA1 14 ALA A 345 ? HIS A 347 ? ALA A 371 HIS A 373 AA1 15 THR A 372 ? ASN A 374 ? THR A 398 ASN A 400 AA1 16 ILE A 396 ? TYR A 398 ? ILE A 422 TYR A 424 AA1 17 ALA A 459 ? ASP A 461 ? ALA A 485 ASP A 487 AA1 18 CYS A 483 ? ASN A 485 ? CYS A 509 ASN A 511 AA1 19 TYR A 508 ? ASP A 510 ? TYR A 534 ASP A 536 AA1 20 VAL A 532 ? ASP A 534 ? VAL A 558 ASP A 560 AA1 21 VAL A 562 ? ASN A 564 ? VAL A 588 ASN A 590 AA1 22 GLU A 586 ? VAL A 588 ? GLU A 612 VAL A 614 AA1 23 ARG A 617 ? ASP A 619 ? ARG A 643 ASP A 645 AA1 24 GLU A 642 ? HIS A 644 ? GLU A 668 HIS A 670 AA1 25 LEU A 666 ? ASP A 668 ? LEU A 692 ASP A 694 AA1 26 THR A 690 ? LEU A 692 ? THR A 716 LEU A 718 AA1 27 HIS A 714 ? ASP A 716 ? HIS A 740 ASP A 742 AA1 28 MET A 740 ? GLU A 742 ? MET A 766 GLU A 768 AA2 1 HIS A 51 ? ILE A 52 ? HIS A 77 ILE A 78 AA2 2 ASN A 89 ? ILE A 90 ? ASN A 115 ILE A 116 AA3 1 ASN A 134 ? ILE A 135 ? ASN A 160 ILE A 161 AA3 2 ASN A 165 ? ILE A 166 ? ASN A 191 ILE A 192 AA4 1 TYR A 210 ? ILE A 211 ? TYR A 236 ILE A 237 AA4 2 ASN A 251 ? ILE A 252 ? ASN A 277 ILE A 278 AA5 1 GLU A 355 ? LEU A 356 ? GLU A 381 LEU A 382 AA5 2 GLN A 382 ? ILE A 383 ? GLN A 408 ILE A 409 AA6 1 GLU A 580 ? SER A 581 ? GLU A 606 SER A 607 AA6 2 GLY A 611 ? LEU A 612 ? GLY A 637 LEU A 638 AA7 1 PHE A 748 ? GLU A 749 ? PHE A 774 GLU A 775 AA7 2 CYS A 777 ? SER A 779 ? CYS A 803 SER A 805 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N ASP A 11 ? N ASP A 37 O GLU A 22 ? O GLU A 48 AA1 2 3 N ALA A 21 ? N ALA A 47 O ASP A 43 ? O ASP A 69 AA1 3 4 N LEU A 42 ? N LEU A 68 O LYS A 65 ? O LYS A 91 AA1 4 5 N ILE A 66 ? N ILE A 92 O LEU A 105 ? O LEU A 131 AA1 5 6 N LEU A 104 ? N LEU A 130 O GLU A 124 ? O GLU A 150 AA1 6 7 N LEU A 125 ? N LEU A 151 O ASN A 148 ? O ASN A 174 AA1 7 8 N LEU A 149 ? N LEU A 175 O LEU A 179 ? O LEU A 205 AA1 8 9 N LEU A 180 ? N LEU A 206 O LYS A 200 ? O LYS A 226 AA1 9 10 N LEU A 201 ? N LEU A 227 O LEU A 224 ? O LEU A 250 AA1 10 11 N LEU A 225 ? N LEU A 251 O TYR A 265 ? O TYR A 291 AA1 11 12 N LEU A 266 ? N LEU A 292 O VAL A 289 ? O VAL A 315 AA1 12 13 N LEU A 290 ? N LEU A 316 O ILE A 315 ? O ILE A 341 AA1 13 14 N LEU A 316 ? N LEU A 342 O HIS A 347 ? O HIS A 373 AA1 14 15 N LEU A 346 ? N LEU A 372 O ASN A 374 ? O ASN A 400 AA1 15 16 N ILE A 373 ? N ILE A 399 O TYR A 398 ? O TYR A 424 AA1 16 17 N ILE A 397 ? N ILE A 423 O ALA A 459 ? O ALA A 485 AA1 17 18 N LEU A 460 ? N LEU A 486 O CYS A 483 ? O CYS A 509 AA1 18 19 N LEU A 484 ? N LEU A 510 O ASP A 510 ? O ASP A 536 AA1 19 20 N LEU A 509 ? N LEU A 535 O VAL A 532 ? O VAL A 558 AA1 20 21 N LEU A 533 ? N LEU A 559 O VAL A 562 ? O VAL A 588 AA1 21 22 N LEU A 563 ? N LEU A 589 O GLU A 586 ? O GLU A 612 AA1 22 23 N LEU A 587 ? N LEU A 613 O ASP A 619 ? O ASP A 645 AA1 23 24 N LEU A 618 ? N LEU A 644 O HIS A 644 ? O HIS A 670 AA1 24 25 N LEU A 643 ? N LEU A 669 O ASP A 668 ? O ASP A 694 AA1 25 26 N LEU A 667 ? N LEU A 693 O LEU A 692 ? O LEU A 718 AA1 26 27 N LEU A 691 ? N LEU A 717 O ASP A 716 ? O ASP A 742 AA1 27 28 N LEU A 715 ? N LEU A 741 O GLU A 742 ? O GLU A 768 AA2 1 2 N ILE A 52 ? N ILE A 78 O ASN A 89 ? O ASN A 115 AA3 1 2 N ILE A 135 ? N ILE A 161 O ASN A 165 ? O ASN A 191 AA4 1 2 N ILE A 211 ? N ILE A 237 O ASN A 251 ? O ASN A 277 AA5 1 2 N LEU A 356 ? N LEU A 382 O GLN A 382 ? O GLN A 408 AA6 1 2 N SER A 581 ? N SER A 607 O GLY A 611 ? O GLY A 637 AA7 1 2 N PHE A 748 ? N PHE A 774 O ALA A 778 ? O ALA A 804 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A SO4 918 ? 3 'binding site for residue SO4 A 918' AC2 Software A SO4 919 ? 4 'binding site for residue SO4 A 919' AC3 Software A SO4 920 ? 2 'binding site for residue SO4 A 920' AC4 Software A MES 921 ? 6 'binding site for residue MES A 921' AC5 Software A NAG 901 ? 2 'binding site for Mono-Saccharide NAG A 901 bound to ASN A 285' AC6 Software A ASN 293 ? 11 'binding site for Poly-Saccharide residues NAG A 902 through MAN A 905 bound to ASN A 293' AC7 Software A NAG 906 ? 6 'binding site for Mono-Saccharide NAG A 906 bound to ASN A 395' AC8 Software A NAG 907 ? 5 'binding site for Mono-Saccharide NAG A 907 bound to ASN A 416' AC9 Software A ASN 511 ? 7 'binding site for Poly-Saccharide residues NAG A 908 through NAG A 909 bound to ASN A 511' AD1 Software A NAG 910 ? 3 'binding site for Mono-Saccharide NAG A 910 bound to ASN A 546' AD2 Software A NAG 911 ? 2 'binding site for Mono-Saccharide NAG A 911 bound to ASN A 582' AD3 Software A ASN 590 ? 12 'binding site for Poly-Saccharide residues NAG A 912 through MAN A 916 bound to ASN A 590' AD4 Software A NAG 917 ? 4 'binding site for Mono-Saccharide NAG A 917 bound to ASN A 640' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 3 LYS A 651 ? LYS A 677 . ? 1_555 ? 2 AC1 3 LYS A 673 ? LYS A 699 . ? 1_555 ? 3 AC1 3 ARG A 697 ? ARG A 723 . ? 1_555 ? 4 AC2 4 PHE A 255 ? PHE A 281 . ? 1_555 ? 5 AC2 4 GLN A 258 ? GLN A 284 . ? 1_555 ? 6 AC2 4 LYS A 282 ? LYS A 308 . ? 1_555 ? 7 AC2 4 ASN A 283 ? ASN A 309 . ? 1_555 ? 8 AC3 2 LYS A 282 ? LYS A 308 . ? 5_555 ? 9 AC3 2 LYS A 339 ? LYS A 365 . ? 1_555 ? 10 AC4 6 ARG A 264 ? ARG A 290 . ? 1_555 ? 11 AC4 6 HIS A 286 ? HIS A 312 . ? 5_555 ? 12 AC4 6 HIS A 286 ? HIS A 312 . ? 1_555 ? 13 AC4 6 LYS A 288 ? LYS A 314 . ? 1_555 ? 14 AC4 6 ARG A 312 ? ARG A 338 . ? 5_555 ? 15 AC4 6 ARG A 312 ? ARG A 338 . ? 1_555 ? 16 AC5 2 GLN A 258 ? GLN A 284 . ? 1_555 ? 17 AC5 2 ASN A 259 ? ASN A 285 . ? 1_555 ? 18 AC6 11 LYS A 200 ? LYS A 226 . ? 1_555 ? 19 AC6 11 SER A 204 ? SER A 230 . ? 1_555 ? 20 AC6 11 LEU A 224 ? LEU A 250 . ? 1_555 ? 21 AC6 11 ASP A 226 ? ASP A 252 . ? 1_555 ? 22 AC6 11 SER A 228 ? SER A 254 . ? 1_555 ? 23 AC6 11 TYR A 265 ? TYR A 291 . ? 1_555 ? 24 AC6 11 ASN A 267 ? ASN A 293 . ? 1_555 ? 25 AC6 11 ASP A 291 ? ASP A 317 . ? 1_555 ? 26 AC6 11 SER A 439 ? SER A 465 . ? 1_555 ? 27 AC6 11 ASN A 440 ? ASN A 466 . ? 1_555 ? 28 AC6 11 PHE A 441 ? PHE A 467 . ? 1_555 ? 29 AC7 6 ILE A 220 ? ILE A 246 . ? 5_555 ? 30 AC7 6 ASN A 221 ? ASN A 247 . ? 5_555 ? 31 AC7 6 GLN A 262 ? GLN A 288 . ? 5_555 ? 32 AC7 6 ARG A 344 ? ARG A 370 . ? 1_555 ? 33 AC7 6 ASN A 369 ? ASN A 395 . ? 1_555 ? 34 AC7 6 HOH W . ? HOH A 1068 . ? 1_555 ? 35 AC8 5 GLU A 358 ? GLU A 384 . ? 1_555 ? 36 AC8 5 GLN A 362 ? GLN A 388 . ? 1_555 ? 37 AC8 5 MET A 365 ? MET A 391 . ? 1_555 ? 38 AC8 5 ASN A 390 ? ASN A 416 . ? 1_555 ? 39 AC8 5 HOH W . ? HOH A 1013 . ? 1_555 ? 40 AC9 7 ILE A 449 ? ILE A 475 . ? 1_555 ? 41 AC9 7 LYS A 450 ? LYS A 476 . ? 1_555 ? 42 AC9 7 SER A 463 ? SER A 489 . ? 1_555 ? 43 AC9 7 ASN A 485 ? ASN A 511 . ? 1_555 ? 44 AC9 7 TYR A 508 ? TYR A 534 . ? 1_555 ? 45 AC9 7 ASP A 510 ? ASP A 536 . ? 1_555 ? 46 AC9 7 HOH W . ? HOH A 1054 . ? 1_555 ? 47 AD1 3 SER A 496 ? SER A 522 . ? 1_555 ? 48 AD1 3 ASN A 520 ? ASN A 546 . ? 1_555 ? 49 AD1 3 SER A 522 ? SER A 548 . ? 1_555 ? 50 AD2 2 GLN A 555 ? GLN A 581 . ? 1_555 ? 51 AD2 2 ASN A 556 ? ASN A 582 . ? 1_555 ? 52 AD3 12 LYS A 450 ? LYS A 476 . ? 1_555 ? 53 AD3 12 GLN A 452 ? GLN A 478 . ? 1_555 ? 54 AD3 12 TYR A 508 ? TYR A 534 . ? 1_555 ? 55 AD3 12 ASP A 534 ? ASP A 560 . ? 1_555 ? 56 AD3 12 ASN A 564 ? ASN A 590 . ? 1_555 ? 57 AD3 12 GLU A 586 ? GLU A 612 . ? 1_555 ? 58 AD3 12 VAL A 588 ? VAL A 614 . ? 1_555 ? 59 AD3 12 HOH W . ? HOH A 1006 . ? 1_555 ? 60 AD3 12 HOH W . ? HOH A 1019 . ? 1_555 ? 61 AD3 12 HOH W . ? HOH A 1025 . ? 1_555 ? 62 AD3 12 HOH W . ? HOH A 1026 . ? 1_555 ? 63 AD3 12 HOH W . ? HOH A 1052 . ? 1_555 ? 64 AD4 4 LYS A 582 ? LYS A 608 . ? 1_555 ? 65 AD4 4 SER A 583 ? SER A 609 . ? 1_555 ? 66 AD4 4 VAL A 585 ? VAL A 611 . ? 1_555 ? 67 AD4 4 ASN A 614 ? ASN A 640 . ? 1_555 ? # _atom_sites.entry_id 5HDH _atom_sites.fract_transf_matrix[1][1] 0.005830 _atom_sites.fract_transf_matrix[1][2] 0.003366 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] -0.000000 _atom_sites.fract_transf_matrix[2][2] 0.006732 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] -0.000000 _atom_sites.fract_transf_matrix[3][3] 0.003319 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . SER A 1 7 ? -101.381 -23.669 15.077 1.00 127.09 ? 33 SER A N 1 ATOM 2 C CA . SER A 1 7 ? -100.110 -24.173 14.473 1.00 129.36 ? 33 SER A CA 1 ATOM 3 C C . SER A 1 7 ? -99.341 -24.979 15.528 1.00 129.05 ? 33 SER A C 1 ATOM 4 O O . SER A 1 7 ? -98.863 -24.425 16.517 1.00 145.74 ? 33 SER A O 1 ATOM 5 C CB . SER A 1 7 ? -99.284 -23.007 13.890 1.00 136.03 ? 33 SER A CB 1 ATOM 6 O OG . SER A 1 7 ? -99.018 -21.992 14.846 1.00 120.91 ? 33 SER A OG 1 ATOM 7 N N . TYR A 1 8 ? -99.283 -26.299 15.326 1.00 126.45 ? 34 TYR A N 1 ATOM 8 C CA . TYR A 1 8 ? -98.619 -27.240 16.253 1.00 114.84 ? 34 TYR A CA 1 ATOM 9 C C . TYR A 1 8 ? -98.000 -28.443 15.483 1.00 113.91 ? 34 TYR A C 1 ATOM 10 O O . TYR A 1 8 ? -98.480 -28.791 14.403 1.00 120.76 ? 34 TYR A O 1 ATOM 11 C CB . TYR A 1 8 ? -99.685 -27.748 17.244 1.00 104.99 ? 34 TYR A CB 1 ATOM 12 C CG . TYR A 1 8 ? -99.234 -28.787 18.266 1.00 115.68 ? 34 TYR A CG 1 ATOM 13 C CD1 . TYR A 1 8 ? -99.134 -28.473 19.624 1.00 118.46 ? 34 TYR A CD1 1 ATOM 14 C CD2 . TYR A 1 8 ? -98.881 -30.078 17.869 1.00 117.64 ? 34 TYR A CD2 1 ATOM 15 C CE1 . TYR A 1 8 ? -98.734 -29.423 20.555 1.00 112.63 ? 34 TYR A CE1 1 ATOM 16 C CE2 . TYR A 1 8 ? -98.471 -31.030 18.792 1.00 108.64 ? 34 TYR A CE2 1 ATOM 17 C CZ . TYR A 1 8 ? -98.405 -30.700 20.132 1.00 113.66 ? 34 TYR A CZ 1 ATOM 18 O OH . TYR A 1 8 ? -98.005 -31.646 21.050 1.00 117.86 ? 34 TYR A OH 1 ATOM 19 N N . PRO A 1 9 ? -96.882 -29.002 15.965 1.00 124.78 ? 35 PRO A N 1 ATOM 20 C CA . PRO A 1 9 ? -96.196 -28.521 17.167 1.00 137.95 ? 35 PRO A CA 1 ATOM 21 C C . PRO A 1 9 ? -95.202 -27.410 16.801 1.00 146.05 ? 35 PRO A C 1 ATOM 22 O O . PRO A 1 9 ? -94.627 -26.760 17.676 1.00 136.39 ? 35 PRO A O 1 ATOM 23 C CB . PRO A 1 9 ? -95.447 -29.768 17.655 1.00 125.30 ? 35 PRO A CB 1 ATOM 24 C CG . PRO A 1 9 ? -95.127 -30.515 16.402 1.00 117.01 ? 35 PRO A CG 1 ATOM 25 C CD . PRO A 1 9 ? -96.274 -30.251 15.451 1.00 115.37 ? 35 PRO A CD 1 ATOM 26 N N . CYS A 1 10 ? -95.046 -27.189 15.499 1.00 144.31 ? 36 CYS A N 1 ATOM 27 C CA . CYS A 1 10 ? -94.137 -26.196 14.966 1.00 140.14 ? 36 CYS A CA 1 ATOM 28 C C . CYS A 1 10 ? -94.782 -24.815 14.938 1.00 135.85 ? 36 CYS A C 1 ATOM 29 O O . CYS A 1 10 ? -95.933 -24.671 14.523 1.00 143.71 ? 36 CYS A O 1 ATOM 30 C CB . CYS A 1 10 ? -93.786 -26.589 13.536 1.00 145.60 ? 36 CYS A CB 1 ATOM 31 S SG . CYS A 1 10 ? -93.336 -28.333 13.350 1.00 155.69 ? 36 CYS A SG 1 ATOM 32 N N . ASP A 1 11 ? -94.019 -23.796 15.334 1.00 143.34 ? 37 ASP A N 1 ATOM 33 C CA . ASP A 1 11 ? -94.511 -22.420 15.341 1.00 134.65 ? 37 ASP A CA 1 ATOM 34 C C . ASP A 1 11 ? -94.196 -21.792 13.997 1.00 135.42 ? 37 ASP A C 1 ATOM 35 O O . ASP A 1 11 ? -93.054 -21.433 13.731 1.00 149.79 ? 37 ASP A O 1 ATOM 36 C CB . ASP A 1 11 ? -93.861 -21.603 16.459 1.00 123.93 ? 37 ASP A CB 1 ATOM 37 C CG . ASP A 1 11 ? -94.152 -22.162 17.839 1.00 127.10 ? 37 ASP A CG 1 ATOM 38 O OD1 . ASP A 1 11 ? -94.474 -23.364 17.951 1.00 134.48 ? 37 ASP A OD1 1 ATOM 39 O OD2 . ASP A 1 11 ? -94.005 -21.414 18.822 1.00 123.21 ? 37 ASP A OD2 1 ATOM 40 N N . GLU A 1 12 ? -95.199 -21.707 13.133 1.00 134.73 ? 38 GLU A N 1 ATOM 41 C CA . GLU A 1 12 ? -95.005 -21.126 11.816 1.00 137.89 ? 38 GLU A CA 1 ATOM 42 C C . GLU A 1 12 ? -94.934 -19.616 11.943 1.00 141.60 ? 38 GLU A C 1 ATOM 43 O O . GLU A 1 12 ? -95.924 -18.973 12.286 1.00 139.50 ? 38 GLU A O 1 ATOM 44 C CB . GLU A 1 12 ? -96.145 -21.519 10.865 1.00 151.78 ? 38 GLU A CB 1 ATOM 45 C CG . GLU A 1 12 ? -96.292 -23.021 10.634 1.00 159.59 ? 38 GLU A CG 1 ATOM 46 C CD . GLU A 1 12 ? -97.381 -23.368 9.623 1.00 151.35 ? 38 GLU A CD 1 ATOM 47 O OE1 . GLU A 1 12 ? -97.963 -22.436 9.024 1.00 124.70 ? 38 GLU A OE1 1 ATOM 48 O OE2 . GLU A 1 12 ? -97.632 -24.575 9.401 1.00 145.41 ? 38 GLU A OE2 1 ATOM 49 N N . LYS A 1 13 ? -93.749 -19.053 11.717 1.00 154.91 ? 39 LYS A N 1 ATOM 50 C CA . LYS A 1 13 ? -93.573 -17.607 11.801 1.00 152.39 ? 39 LYS A CA 1 ATOM 51 C C . LYS A 1 13 ? -93.600 -17.091 10.366 1.00 147.80 ? 39 LYS A C 1 ATOM 52 O O . LYS A 1 13 ? -93.229 -17.809 9.436 1.00 139.22 ? 39 LYS A O 1 ATOM 53 C CB . LYS A 1 13 ? -92.254 -17.250 12.491 1.00 156.95 ? 39 LYS A CB 1 ATOM 54 C CG . LYS A 1 13 ? -92.131 -15.786 12.910 1.00 168.85 ? 39 LYS A CG 1 ATOM 55 C CD . LYS A 1 13 ? -93.163 -15.432 13.982 1.00 170.94 ? 39 LYS A CD 1 ATOM 56 C CE . LYS A 1 13 ? -93.032 -13.996 14.472 1.00 159.93 ? 39 LYS A CE 1 ATOM 57 N NZ . LYS A 1 13 ? -94.009 -13.692 15.557 1.00 143.37 ? 39 LYS A NZ 1 ATOM 58 N N . LYS A 1 14 ? -93.991 -15.836 10.193 1.00 152.58 ? 40 LYS A N 1 ATOM 59 C CA . LYS A 1 14 ? -94.097 -15.243 8.861 1.00 158.71 ? 40 LYS A CA 1 ATOM 60 C C . LYS A 1 14 ? -93.139 -14.090 8.588 1.00 155.28 ? 40 LYS A C 1 ATOM 61 O O . LYS A 1 14 ? -92.611 -13.473 9.512 1.00 163.07 ? 40 LYS A O 1 ATOM 62 C CB . LYS A 1 14 ? -95.550 -14.814 8.571 1.00 165.21 ? 40 LYS A CB 1 ATOM 63 C CG . LYS A 1 14 ? -96.235 -13.974 9.654 1.00 166.99 ? 40 LYS A CG 1 ATOM 64 C CD . LYS A 1 14 ? -96.559 -14.794 10.898 1.00 160.82 ? 40 LYS A CD 1 ATOM 65 C CE . LYS A 1 14 ? -97.264 -13.977 11.961 1.00 155.56 ? 40 LYS A CE 1 ATOM 66 N NZ . LYS A 1 14 ? -97.583 -14.831 13.138 1.00 158.65 ? 40 LYS A NZ 1 ATOM 67 N N . GLN A 1 15 ? -92.795 -13.920 7.322 1.00 153.40 ? 41 GLN A N 1 ATOM 68 C CA . GLN A 1 15 ? -91.878 -12.873 6.916 1.00 162.71 ? 41 GLN A CA 1 ATOM 69 C C . GLN A 1 15 ? -90.427 -13.348 6.983 1.00 160.46 ? 41 GLN A C 1 ATOM 70 O O . GLN A 1 15 ? -90.122 -14.285 7.715 1.00 123.60 ? 41 GLN A O 1 ATOM 71 C CB . GLN A 1 15 ? -92.065 -11.636 7.787 1.00 163.53 ? 41 GLN A CB 1 ATOM 72 C CG . GLN A 1 15 ? -92.745 -10.483 7.075 1.00 159.35 ? 41 GLN A CG 1 ATOM 73 C CD . GLN A 1 15 ? -91.788 -9.357 6.758 1.00 161.59 ? 41 GLN A CD 1 ATOM 74 O OE1 . GLN A 1 15 ? -90.617 -9.409 7.121 1.00 165.86 ? 41 GLN A OE1 1 ATOM 75 N NE2 . GLN A 1 15 ? -92.286 -8.326 6.082 1.00 153.28 ? 41 GLN A NE2 1 ATOM 76 N N . ASN A 1 16 ? -89.526 -12.687 6.253 1.00 167.63 ? 42 ASN A N 1 ATOM 77 C CA . ASN A 1 16 ? -89.869 -11.587 5.358 1.00 167.44 ? 42 ASN A CA 1 ATOM 78 C C . ASN A 1 16 ? -89.981 -12.067 3.925 1.00 169.66 ? 42 ASN A C 1 ATOM 79 O O . ASN A 1 16 ? -89.004 -12.477 3.312 1.00 175.89 ? 42 ASN A O 1 ATOM 80 C CB . ASN A 1 16 ? -88.804 -10.493 5.433 1.00 156.11 ? 42 ASN A CB 1 ATOM 81 C CG . ASN A 1 16 ? -87.395 -11.040 5.323 1.00 146.22 ? 42 ASN A CG 1 ATOM 82 O OD1 . ASN A 1 16 ? -87.199 -12.233 5.098 1.00 151.06 ? 42 ASN A OD1 1 ATOM 83 N ND2 . ASN A 1 16 ? -86.405 -10.172 5.494 1.00 123.36 ? 42 ASN A ND2 1 ATOM 84 N N . ASP A 1 17 ? -91.185 -12.023 3.386 1.00 157.55 ? 43 ASP A N 1 ATOM 85 C CA . ASP A 1 17 ? -91.368 -12.358 1.992 1.00 157.67 ? 43 ASP A CA 1 ATOM 86 C C . ASP A 1 17 ? -91.177 -13.853 1.794 1.00 149.54 ? 43 ASP A C 1 ATOM 87 O O . ASP A 1 17 ? -91.098 -14.337 0.673 1.00 139.39 ? 43 ASP A O 1 ATOM 88 C CB . ASP A 1 17 ? -90.392 -11.557 1.139 1.00 160.19 ? 43 ASP A CB 1 ATOM 89 C CG . ASP A 1 17 ? -90.397 -10.083 1.492 1.00 155.10 ? 43 ASP A CG 1 ATOM 90 O OD1 . ASP A 1 17 ? -89.815 -9.273 0.741 1.00 140.56 ? 43 ASP A OD1 1 ATOM 91 O OD2 . ASP A 1 17 ? -90.993 -9.734 2.529 1.00 144.95 ? 43 ASP A OD2 1 ATOM 92 N N . SER A 1 18 ? -91.109 -14.578 2.902 1.00 146.14 ? 44 SER A N 1 ATOM 93 C CA . SER A 1 18 ? -91.101 -16.025 2.892 1.00 134.63 ? 44 SER A CA 1 ATOM 94 C C . SER A 1 18 ? -91.634 -16.467 4.235 1.00 138.65 ? 44 SER A C 1 ATOM 95 O O . SER A 1 18 ? -91.566 -15.715 5.198 1.00 137.02 ? 44 SER A O 1 ATOM 96 C CB . SER A 1 18 ? -89.690 -16.539 2.700 1.00 113.15 ? 44 SER A CB 1 ATOM 97 O OG . SER A 1 18 ? -88.795 -15.765 3.459 1.00 102.82 ? 44 SER A OG 1 ATOM 98 N N . VAL A 1 19 ? -92.164 -17.680 4.307 1.00 144.78 ? 45 VAL A N 1 ATOM 99 C CA . VAL A 1 19 ? -92.613 -18.244 5.595 1.00 146.49 ? 45 VAL A CA 1 ATOM 100 C C . VAL A 1 19 ? -91.852 -19.501 6.009 1.00 127.55 ? 45 VAL A C 1 ATOM 101 O O . VAL A 1 19 ? -91.800 -20.499 5.285 1.00 99.17 ? 45 VAL A O 1 ATOM 102 C CB . VAL A 1 19 ? -94.128 -18.536 5.614 1.00 152.12 ? 45 VAL A CB 1 ATOM 103 C CG1 . VAL A 1 19 ? -94.512 -19.278 6.890 1.00 149.23 ? 45 VAL A CG1 1 ATOM 104 C CG2 . VAL A 1 19 ? -94.918 -17.239 5.481 1.00 145.11 ? 45 VAL A CG2 1 ATOM 105 N N . ILE A 1 20 ? -91.391 -19.468 7.252 1.00 122.43 ? 46 ILE A N 1 ATOM 106 C CA . ILE A 1 20 ? -90.612 -20.535 7.845 1.00 122.77 ? 46 ILE A CA 1 ATOM 107 C C . ILE A 1 20 ? -91.396 -21.196 8.967 1.00 116.20 ? 46 ILE A C 1 ATOM 108 O O . ILE A 1 20 ? -92.272 -20.577 9.583 1.00 111.72 ? 46 ILE A O 1 ATOM 109 C CB . ILE A 1 20 ? -89.275 -19.944 8.378 1.00 139.45 ? 46 ILE A CB 1 ATOM 110 C CG1 . ILE A 1 20 ? -88.304 -21.018 8.890 1.00 148.44 ? 46 ILE A CG1 1 ATOM 111 C CG2 . ILE A 1 20 ? -89.541 -18.911 9.475 1.00 128.65 ? 46 ILE A CG2 1 ATOM 112 C CD1 . ILE A 1 20 ? -88.653 -21.633 10.228 1.00 152.59 ? 46 ILE A CD1 1 ATOM 113 N N . ALA A 1 21 ? -91.109 -22.476 9.183 1.00 104.70 ? 47 ALA A N 1 ATOM 114 C CA . ALA A 1 21 ? -91.750 -23.256 10.229 1.00 108.33 ? 47 ALA A CA 1 ATOM 115 C C . ALA A 1 21 ? -90.722 -23.580 11.324 1.00 106.25 ? 47 ALA A C 1 ATOM 116 O O . ALA A 1 21 ? -89.975 -24.560 11.217 1.00 104.92 ? 47 ALA A O 1 ATOM 117 C CB . ALA A 1 21 ? -92.330 -24.528 9.639 1.00 107.05 ? 47 ALA A CB 1 ATOM 118 N N . GLU A 1 22 ? -90.661 -22.720 12.345 1.00 105.85 ? 48 GLU A N 1 ATOM 119 C CA . GLU A 1 22 ? -89.721 -22.887 13.463 1.00 107.99 ? 48 GLU A CA 1 ATOM 120 C C . GLU A 1 22 ? -90.137 -24.141 14.181 1.00 96.77 ? 48 GLU A C 1 ATOM 121 O O . GLU A 1 22 ? -91.101 -24.104 14.932 1.00 93.35 ? 48 GLU A O 1 ATOM 122 C CB . GLU A 1 22 ? -89.818 -21.712 14.451 1.00 119.25 ? 48 GLU A CB 1 ATOM 123 C CG . GLU A 1 22 ? -89.572 -20.323 13.878 1.00 116.90 ? 48 GLU A CG 1 ATOM 124 C CD . GLU A 1 22 ? -89.733 -19.239 14.934 1.00 133.87 ? 48 GLU A CD 1 ATOM 125 O OE1 . GLU A 1 22 ? -89.846 -18.047 14.570 1.00 137.79 ? 48 GLU A OE1 1 ATOM 126 O OE2 . GLU A 1 22 ? -89.809 -19.588 16.133 1.00 142.15 ? 48 GLU A OE2 1 ATOM 127 N N . CYS A 1 23 ? -89.386 -25.228 14.038 1.00 105.08 ? 49 CYS A N 1 ATOM 128 C CA . CYS A 1 23 ? -89.803 -26.470 14.682 1.00 115.56 ? 49 CYS A CA 1 ATOM 129 C C . CYS A 1 23 ? -88.653 -27.296 15.234 1.00 111.91 ? 49 CYS A C 1 ATOM 130 O O . CYS A 1 23 ? -88.515 -28.488 14.927 1.00 111.75 ? 49 CYS A O 1 ATOM 131 C CB . CYS A 1 23 ? -90.558 -27.296 13.655 1.00 127.52 ? 49 CYS A CB 1 ATOM 132 S SG . CYS A 1 23 ? -91.594 -28.568 14.372 1.00 161.65 ? 49 CYS A SG 1 ATOM 133 N N . SER A 1 24 ? -87.860 -26.681 16.093 1.00 109.80 ? 50 SER A N 1 ATOM 134 C CA . SER A 1 24 ? -86.724 -27.362 16.674 1.00 107.22 ? 50 SER A CA 1 ATOM 135 C C . SER A 1 24 ? -86.840 -27.492 18.174 1.00 97.85 ? 50 SER A C 1 ATOM 136 O O . SER A 1 24 ? -87.589 -26.768 18.836 1.00 82.22 ? 50 SER A O 1 ATOM 137 C CB . SER A 1 24 ? -85.440 -26.617 16.329 1.00 103.96 ? 50 SER A CB 1 ATOM 138 O OG . SER A 1 24 ? -85.495 -25.294 16.812 1.00 109.33 ? 50 SER A OG 1 ATOM 139 N N . ASN A 1 25 ? -86.101 -28.448 18.703 1.00 95.62 ? 51 ASN A N 1 ATOM 140 C CA . ASN A 1 25 ? -86.083 -28.691 20.117 1.00 102.65 ? 51 ASN A CA 1 ATOM 141 C C . ASN A 1 25 ? -87.484 -29.008 20.650 1.00 111.90 ? 51 ASN A C 1 ATOM 142 O O . ASN A 1 25 ? -87.904 -28.455 21.664 1.00 100.80 ? 51 ASN A O 1 ATOM 143 C CB . ASN A 1 25 ? -85.507 -27.471 20.826 1.00 102.39 ? 51 ASN A CB 1 ATOM 144 C CG . ASN A 1 25 ? -85.113 -27.765 22.248 1.00 109.19 ? 51 ASN A CG 1 ATOM 145 O OD1 . ASN A 1 25 ? -84.762 -28.901 22.588 1.00 113.08 ? 51 ASN A OD1 1 ATOM 146 N ND2 . ASN A 1 25 ? -85.061 -26.728 23.065 1.00 105.49 ? 51 ASN A ND2 1 ATOM 147 N N . ARG A 1 26 ? -88.242 -29.805 19.893 1.00 125.34 ? 52 ARG A N 1 ATOM 148 C CA . ARG A 1 26 ? -89.585 -30.222 20.310 1.00 112.89 ? 52 ARG A CA 1 ATOM 149 C C . ARG A 1 26 ? -89.665 -31.710 20.653 1.00 118.23 ? 52 ARG A C 1 ATOM 150 O O . ARG A 1 26 ? -90.752 -32.272 20.693 1.00 123.74 ? 52 ARG A O 1 ATOM 151 C CB . ARG A 1 26 ? -90.691 -29.918 19.296 1.00 111.50 ? 52 ARG A CB 1 ATOM 152 C CG . ARG A 1 26 ? -91.224 -28.496 19.208 1.00 113.00 ? 52 ARG A CG 1 ATOM 153 C CD . ARG A 1 26 ? -90.507 -27.595 18.222 1.00 128.79 ? 52 ARG A CD 1 ATOM 154 N NE . ARG A 1 26 ? -91.353 -26.424 17.963 1.00 142.06 ? 52 ARG A NE 1 ATOM 155 C CZ . ARG A 1 26 ? -91.242 -25.236 18.557 1.00 138.41 ? 52 ARG A CZ 1 ATOM 156 N NH1 . ARG A 1 26 ? -92.111 -24.276 18.264 1.00 134.58 ? 52 ARG A NH1 1 ATOM 157 N NH2 . ARG A 1 26 ? -90.281 -25.000 19.442 1.00 138.95 ? 52 ARG A NH2 1 ATOM 158 N N . ARG A 1 27 ? -88.525 -32.356 20.860 1.00 120.63 ? 53 ARG A N 1 ATOM 159 C CA . ARG A 1 27 ? -88.510 -33.776 21.216 1.00 116.16 ? 53 ARG A CA 1 ATOM 160 C C . ARG A 1 27 ? -89.047 -34.711 20.145 1.00 115.61 ? 53 ARG A C 1 ATOM 161 O O . ARG A 1 27 ? -89.286 -35.883 20.418 1.00 127.37 ? 53 ARG A O 1 ATOM 162 C CB . ARG A 1 27 ? -89.296 -34.005 22.517 1.00 112.10 ? 53 ARG A CB 1 ATOM 163 C CG . ARG A 1 27 ? -88.651 -33.387 23.745 1.00 120.06 ? 53 ARG A CG 1 ATOM 164 C CD . ARG A 1 27 ? -89.348 -33.811 25.028 1.00 116.65 ? 53 ARG A CD 1 ATOM 165 N NE . ARG A 1 27 ? -90.616 -33.130 25.305 1.00 126.84 ? 53 ARG A NE 1 ATOM 166 C CZ . ARG A 1 27 ? -90.734 -32.076 26.119 1.00 138.38 ? 53 ARG A CZ 1 ATOM 167 N NH1 . ARG A 1 27 ? -89.670 -31.598 26.757 1.00 146.19 ? 53 ARG A NH1 1 ATOM 168 N NH2 . ARG A 1 27 ? -91.919 -31.521 26.336 1.00 137.69 ? 53 ARG A NH2 1 ATOM 169 N N . LEU A 1 28 ? -89.102 -34.248 18.906 1.00 107.13 ? 54 LEU A N 1 ATOM 170 C CA . LEU A 1 28 ? -89.644 -35.073 17.839 1.00 104.75 ? 54 LEU A CA 1 ATOM 171 C C . LEU A 1 28 ? -88.751 -36.269 17.519 1.00 121.16 ? 54 LEU A C 1 ATOM 172 O O . LEU A 1 28 ? -87.520 -36.204 17.636 1.00 111.57 ? 54 LEU A O 1 ATOM 173 C CB . LEU A 1 28 ? -89.859 -34.257 16.566 1.00 92.60 ? 54 LEU A CB 1 ATOM 174 C CG . LEU A 1 28 ? -90.443 -32.855 16.772 1.00 105.64 ? 54 LEU A CG 1 ATOM 175 C CD1 . LEU A 1 28 ? -91.024 -32.313 15.478 1.00 96.28 ? 54 LEU A CD1 1 ATOM 176 C CD2 . LEU A 1 28 ? -91.431 -32.763 17.926 1.00 104.48 ? 54 LEU A CD2 1 ATOM 177 N N . GLN A 1 29 ? -89.396 -37.377 17.165 1.00 131.40 ? 55 GLN A N 1 ATOM 178 C CA . GLN A 1 29 ? -88.700 -38.597 16.799 1.00 122.51 ? 55 GLN A CA 1 ATOM 179 C C . GLN A 1 29 ? -88.796 -38.635 15.265 1.00 119.34 ? 55 GLN A C 1 ATOM 180 O O . GLN A 1 29 ? -88.075 -39.386 14.612 1.00 116.18 ? 55 GLN A O 1 ATOM 181 C CB . GLN A 1 29 ? -89.445 -39.826 17.343 1.00 122.01 ? 55 GLN A CB 1 ATOM 182 C CG . GLN A 1 29 ? -89.935 -39.733 18.795 1.00 128.64 ? 55 GLN A CG 1 ATOM 183 C CD . GLN A 1 29 ? -88.898 -40.049 19.873 1.00 141.65 ? 55 GLN A CD 1 ATOM 184 O OE1 . GLN A 1 29 ? -89.027 -39.594 21.014 1.00 133.22 ? 55 GLN A OE1 1 ATOM 185 N NE2 . GLN A 1 29 ? -87.919 -40.889 19.547 1.00 144.97 ? 55 GLN A NE2 1 ATOM 186 N N . GLU A 1 30 ? -89.709 -37.832 14.702 1.00 118.46 ? 56 GLU A N 1 ATOM 187 C CA . GLU A 1 30 ? -89.926 -37.792 13.248 1.00 133.37 ? 56 GLU A CA 1 ATOM 188 C C . GLU A 1 30 ? -90.192 -36.386 12.695 1.00 126.76 ? 56 GLU A C 1 ATOM 189 O O . GLU A 1 30 ? -90.360 -35.431 13.446 1.00 133.38 ? 56 GLU A O 1 ATOM 190 C CB . GLU A 1 30 ? -91.159 -38.620 12.908 1.00 146.04 ? 56 GLU A CB 1 ATOM 191 C CG . GLU A 1 30 ? -92.427 -38.045 13.532 1.00 147.80 ? 56 GLU A CG 1 ATOM 192 C CD . GLU A 1 30 ? -93.686 -38.719 13.042 1.00 154.60 ? 56 GLU A CD 1 ATOM 193 O OE1 . GLU A 1 30 ? -93.594 -39.565 12.128 1.00 160.50 ? 56 GLU A OE1 1 ATOM 194 O OE2 . GLU A 1 30 ? -94.775 -38.356 13.531 1.00 150.47 ? 56 GLU A OE2 1 ATOM 195 N N . VAL A 1 31 ? -90.308 -36.292 11.381 1.00 108.38 ? 57 VAL A N 1 ATOM 196 C CA . VAL A 1 31 ? -90.615 -35.041 10.738 1.00 104.46 ? 57 VAL A CA 1 ATOM 197 C C . VAL A 1 31 ? -92.097 -34.959 10.549 1.00 115.01 ? 57 VAL A C 1 ATOM 198 O O . VAL A 1 31 ? -92.642 -35.730 9.772 1.00 120.80 ? 57 VAL A O 1 ATOM 199 C CB . VAL A 1 31 ? -90.055 -35.045 9.325 1.00 113.45 ? 57 VAL A CB 1 ATOM 200 C CG1 . VAL A 1 31 ? -90.388 -33.760 8.603 1.00 102.34 ? 57 VAL A CG1 1 ATOM 201 C CG2 . VAL A 1 31 ? -88.572 -35.314 9.343 1.00 113.14 ? 57 VAL A CG2 1 ATOM 202 N N . PRO A 1 32 ? -92.753 -33.932 11.244 1.00 119.74 ? 58 PRO A N 1 ATOM 203 C CA . PRO A 1 32 ? -94.211 -33.965 11.065 1.00 126.86 ? 58 PRO A CA 1 ATOM 204 C C . PRO A 1 32 ? -94.600 -33.765 9.626 1.00 135.65 ? 58 PRO A C 1 ATOM 205 O O . PRO A 1 32 ? -94.120 -32.852 8.985 1.00 141.55 ? 58 PRO A O 1 ATOM 206 C CB . PRO A 1 32 ? -94.698 -32.759 11.853 1.00 122.58 ? 58 PRO A CB 1 ATOM 207 C CG . PRO A 1 32 ? -93.731 -32.613 12.942 1.00 124.25 ? 58 PRO A CG 1 ATOM 208 C CD . PRO A 1 32 ? -92.459 -32.758 12.199 1.00 123.83 ? 58 PRO A CD 1 ATOM 209 N N . GLN A 1 33 ? -95.493 -34.607 9.138 1.00 141.10 ? 59 GLN A N 1 ATOM 210 C CA . GLN A 1 33 ? -96.096 -34.437 7.830 1.00 148.75 ? 59 GLN A CA 1 ATOM 211 C C . GLN A 1 33 ? -96.978 -33.216 7.781 1.00 152.59 ? 59 GLN A C 1 ATOM 212 O O . GLN A 1 33 ? -97.104 -32.563 6.755 1.00 158.98 ? 59 GLN A O 1 ATOM 213 C CB . GLN A 1 33 ? -96.861 -35.677 7.430 1.00 148.35 ? 59 GLN A CB 1 ATOM 214 C CG . GLN A 1 33 ? -95.943 -36.854 7.174 1.00 172.12 ? 59 GLN A CG 1 ATOM 215 C CD . GLN A 1 33 ? -95.132 -37.206 8.396 1.00 195.87 ? 59 GLN A CD 1 ATOM 216 O OE1 . GLN A 1 33 ? -95.057 -36.423 9.339 1.00 220.01 ? 59 GLN A OE1 1 ATOM 217 N NE2 . GLN A 1 33 ? -94.529 -38.389 8.394 1.00 197.90 ? 59 GLN A NE2 1 ATOM 218 N N . THR A 1 34 ? -97.608 -32.918 8.901 1.00 151.22 ? 60 THR A N 1 ATOM 219 C CA . THR A 1 34 ? -98.612 -31.886 8.934 1.00 135.37 ? 60 THR A CA 1 ATOM 220 C C . THR A 1 34 ? -97.906 -30.552 9.005 1.00 133.09 ? 60 THR A C 1 ATOM 221 O O . THR A 1 34 ? -97.978 -29.818 9.988 1.00 105.46 ? 60 THR A O 1 ATOM 222 C CB . THR A 1 34 ? -99.454 -32.067 10.184 1.00 137.42 ? 60 THR A CB 1 ATOM 223 O OG1 . THR A 1 34 ? -98.650 -31.731 11.319 1.00 132.33 ? 60 THR A OG1 1 ATOM 224 C CG2 . THR A 1 34 ? -99.872 -33.503 10.306 1.00 147.95 ? 60 THR A CG2 1 ATOM 225 N N . VAL A 1 35 ? -97.212 -30.242 7.924 1.00 142.93 ? 61 VAL A N 1 ATOM 226 C CA . VAL A 1 35 ? -96.448 -29.015 7.845 1.00 139.02 ? 61 VAL A CA 1 ATOM 227 C C . VAL A 1 35 ? -96.994 -28.131 6.737 1.00 136.35 ? 61 VAL A C 1 ATOM 228 O O . VAL A 1 35 ? -96.967 -28.485 5.567 1.00 132.92 ? 61 VAL A O 1 ATOM 229 C CB . VAL A 1 35 ? -94.961 -29.336 7.625 1.00 129.77 ? 61 VAL A CB 1 ATOM 230 C CG1 . VAL A 1 35 ? -94.808 -30.491 6.659 1.00 133.07 ? 61 VAL A CG1 1 ATOM 231 C CG2 . VAL A 1 35 ? -94.178 -28.122 7.165 1.00 130.24 ? 61 VAL A CG2 1 ATOM 232 N N . GLY A 1 36 ? -97.438 -26.951 7.129 1.00 130.94 ? 62 GLY A N 1 ATOM 233 C CA . GLY A 1 36 ? -98.075 -25.997 6.201 1.00 132.62 ? 62 GLY A CA 1 ATOM 234 C C . GLY A 1 36 ? -97.359 -26.008 4.864 1.00 141.56 ? 62 GLY A C 1 ATOM 235 O O . GLY A 1 36 ? -96.144 -25.855 4.823 1.00 164.66 ? 62 GLY A O 1 ATOM 236 N N . LYS A 1 37 ? -98.089 -26.178 3.762 1.00 140.55 ? 63 LYS A N 1 ATOM 237 C CA . LYS A 1 37 ? -97.422 -26.222 2.462 1.00 141.36 ? 63 LYS A CA 1 ATOM 238 C C . LYS A 1 37 ? -96.793 -24.863 2.185 1.00 140.84 ? 63 LYS A C 1 ATOM 239 O O . LYS A 1 37 ? -96.969 -23.908 2.950 1.00 118.35 ? 63 LYS A O 1 ATOM 240 C CB . LYS A 1 37 ? -98.340 -26.603 1.281 1.00 154.83 ? 63 LYS A CB 1 ATOM 241 C CG . LYS A 1 37 ? -99.262 -27.808 1.453 1.00 153.03 ? 63 LYS A CG 1 ATOM 242 C CD . LYS A 1 37 ? -100.562 -27.434 2.153 1.00 150.99 ? 63 LYS A CD 1 ATOM 243 C CE . LYS A 1 37 ? -101.333 -26.421 1.308 1.00 147.32 ? 63 LYS A CE 1 ATOM 244 N NZ . LYS A 1 37 ? -102.614 -25.985 1.918 1.00 154.27 ? 63 LYS A NZ 1 ATOM 245 N N . TYR A 1 38 ? -96.135 -24.774 1.038 1.00 149.33 ? 64 TYR A N 1 ATOM 246 C CA . TYR A 1 38 ? -95.437 -23.570 0.603 1.00 164.78 ? 64 TYR A CA 1 ATOM 247 C C . TYR A 1 38 ? -94.650 -22.909 1.742 1.00 167.82 ? 64 TYR A C 1 ATOM 248 O O . TYR A 1 38 ? -95.008 -21.844 2.254 1.00 164.74 ? 64 TYR A O 1 ATOM 249 C CB . TYR A 1 38 ? -96.331 -22.588 -0.197 1.00 172.56 ? 64 TYR A CB 1 ATOM 250 C CG . TYR A 1 38 ? -97.472 -21.907 0.537 1.00 187.30 ? 64 TYR A CG 1 ATOM 251 C CD1 . TYR A 1 38 ? -97.297 -20.648 1.112 1.00 188.62 ? 64 TYR A CD1 1 ATOM 252 C CD2 . TYR A 1 38 ? -98.754 -22.453 0.539 1.00 184.82 ? 64 TYR A CD2 1 ATOM 253 C CE1 . TYR A 1 38 ? -98.342 -19.992 1.739 1.00 177.65 ? 64 TYR A CE1 1 ATOM 254 C CE2 . TYR A 1 38 ? -99.809 -21.802 1.164 1.00 172.18 ? 64 TYR A CE2 1 ATOM 255 C CZ . TYR A 1 38 ? -99.596 -20.571 1.762 1.00 174.27 ? 64 TYR A CZ 1 ATOM 256 O OH . TYR A 1 38 ? -100.632 -19.912 2.387 1.00 144.75 ? 64 TYR A OH 1 ATOM 257 N N . VAL A 1 39 ? -93.606 -23.617 2.166 1.00 161.69 ? 65 VAL A N 1 ATOM 258 C CA . VAL A 1 39 ? -92.699 -23.162 3.210 1.00 145.90 ? 65 VAL A CA 1 ATOM 259 C C . VAL A 1 39 ? -91.360 -22.938 2.526 1.00 143.11 ? 65 VAL A C 1 ATOM 260 O O . VAL A 1 39 ? -90.973 -23.696 1.626 1.00 128.35 ? 65 VAL A O 1 ATOM 261 C CB . VAL A 1 39 ? -92.546 -24.199 4.339 1.00 143.81 ? 65 VAL A CB 1 ATOM 262 C CG1 . VAL A 1 39 ? -91.487 -23.763 5.339 1.00 145.89 ? 65 VAL A CG1 1 ATOM 263 C CG2 . VAL A 1 39 ? -93.868 -24.391 5.051 1.00 148.30 ? 65 VAL A CG2 1 ATOM 264 N N . THR A 1 40 ? -90.679 -21.867 2.905 1.00 131.60 ? 66 THR A N 1 ATOM 265 C CA . THR A 1 40 ? -89.396 -21.559 2.311 1.00 133.02 ? 66 THR A CA 1 ATOM 266 C C . THR A 1 40 ? -88.385 -22.538 2.884 1.00 131.14 ? 66 THR A C 1 ATOM 267 O O . THR A 1 40 ? -87.648 -23.204 2.146 1.00 111.88 ? 66 THR A O 1 ATOM 268 C CB . THR A 1 40 ? -88.951 -20.122 2.647 1.00 136.31 ? 66 THR A CB 1 ATOM 269 O OG1 . THR A 1 40 ? -90.045 -19.224 2.445 1.00 137.06 ? 66 THR A OG1 1 ATOM 270 C CG2 . THR A 1 40 ? -87.740 -19.695 1.789 1.00 125.07 ? 66 THR A CG2 1 ATOM 271 N N . GLU A 1 41 ? -88.394 -22.661 4.208 1.00 124.18 ? 67 GLU A N 1 ATOM 272 C CA . GLU A 1 41 ? -87.472 -23.550 4.895 1.00 125.31 ? 67 GLU A CA 1 ATOM 273 C C . GLU A 1 41 ? -87.999 -24.049 6.225 1.00 110.74 ? 67 GLU A C 1 ATOM 274 O O . GLU A 1 41 ? -88.857 -23.419 6.846 1.00 97.21 ? 67 GLU A O 1 ATOM 275 C CB . GLU A 1 41 ? -86.147 -22.842 5.113 1.00 140.09 ? 67 GLU A CB 1 ATOM 276 C CG . GLU A 1 41 ? -86.283 -21.491 5.800 1.00 153.29 ? 67 GLU A CG 1 ATOM 277 C CD . GLU A 1 41 ? -84.946 -20.836 6.105 1.00 153.74 ? 67 GLU A CD 1 ATOM 278 O OE1 . GLU A 1 41 ? -83.962 -21.563 6.375 1.00 148.02 ? 67 GLU A OE1 1 ATOM 279 O OE2 . GLU A 1 41 ? -84.905 -19.589 6.175 1.00 125.17 ? 67 GLU A OE2 1 ATOM 280 N N . LEU A 1 42 ? -87.395 -25.138 6.687 1.00 98.83 ? 68 LEU A N 1 ATOM 281 C CA . LEU A 1 42 ? -87.766 -25.791 7.933 1.00 96.84 ? 68 LEU A CA 1 ATOM 282 C C . LEU A 1 42 ? -86.606 -25.940 8.914 1.00 94.85 ? 68 LEU A C 1 ATOM 283 O O . LEU A 1 42 ? -85.504 -26.379 8.552 1.00 100.66 ? 68 LEU A O 1 ATOM 284 C CB . LEU A 1 42 ? -88.250 -27.203 7.618 1.00 118.23 ? 68 LEU A CB 1 ATOM 285 C CG . LEU A 1 42 ? -88.615 -28.057 8.835 1.00 123.77 ? 68 LEU A CG 1 ATOM 286 C CD1 . LEU A 1 42 ? -89.929 -27.601 9.462 1.00 125.09 ? 68 LEU A CD1 1 ATOM 287 C CD2 . LEU A 1 42 ? -88.714 -29.509 8.409 1.00 115.39 ? 68 LEU A CD2 1 ATOM 288 N N . ASP A 1 43 ? -86.920 -25.751 10.185 1.00 88.18 ? 69 ASP A N 1 ATOM 289 C CA . ASP A 1 43 ? -85.935 -25.868 11.239 1.00 96.70 ? 69 ASP A CA 1 ATOM 290 C C . ASP A 1 43 ? -86.238 -27.080 12.144 1.00 102.06 ? 69 ASP A C 1 ATOM 291 O O . ASP A 1 43 ? -87.165 -27.032 12.956 1.00 92.77 ? 69 ASP A O 1 ATOM 292 C CB . ASP A 1 43 ? -85.944 -24.587 12.073 1.00 88.12 ? 69 ASP A CB 1 ATOM 293 C CG . ASP A 1 43 ? -84.926 -24.616 13.175 1.00 90.84 ? 69 ASP A CG 1 ATOM 294 O OD1 . ASP A 1 43 ? -83.915 -25.354 13.034 1.00 78.98 ? 69 ASP A OD1 1 ATOM 295 O OD2 . ASP A 1 43 ? -85.117 -23.869 14.158 1.00 92.17 ? 69 ASP A OD2 1 ATOM 296 N N . LEU A 1 44 ? -85.429 -28.137 12.046 1.00 100.67 ? 70 LEU A N 1 ATOM 297 C CA . LEU A 1 44 ? -85.640 -29.349 12.864 1.00 102.89 ? 70 LEU A CA 1 ATOM 298 C C . LEU A 1 44 ? -84.444 -29.726 13.734 1.00 110.10 ? 70 LEU A C 1 ATOM 299 O O . LEU A 1 44 ? -84.228 -30.907 14.041 1.00 100.00 ? 70 LEU A O 1 ATOM 300 C CB . LEU A 1 44 ? -85.970 -30.539 11.967 1.00 103.69 ? 70 LEU A CB 1 ATOM 301 C CG . LEU A 1 44 ? -87.225 -30.442 11.103 1.00 101.25 ? 70 LEU A CG 1 ATOM 302 C CD1 . LEU A 1 44 ? -87.269 -31.671 10.215 1.00 99.12 ? 70 LEU A CD1 1 ATOM 303 C CD2 . LEU A 1 44 ? -88.496 -30.298 11.938 1.00 96.16 ? 70 LEU A CD2 1 ATOM 304 N N . SER A 1 45 ? -83.677 -28.729 14.148 1.00 104.01 ? 71 SER A N 1 ATOM 305 C CA . SER A 1 45 ? -82.513 -28.980 14.976 1.00 105.19 ? 71 SER A CA 1 ATOM 306 C C . SER A 1 45 ? -82.922 -29.351 16.393 1.00 98.89 ? 71 SER A C 1 ATOM 307 O O . SER A 1 45 ? -84.032 -29.050 16.824 1.00 86.38 ? 71 SER A O 1 ATOM 308 C CB . SER A 1 45 ? -81.632 -27.731 15.027 1.00 110.67 ? 71 SER A CB 1 ATOM 309 O OG . SER A 1 45 ? -82.338 -26.633 15.591 1.00 104.15 ? 71 SER A OG 1 ATOM 310 N N . ASP A 1 46 ? -82.012 -30.009 17.108 1.00 100.84 ? 72 ASP A N 1 ATOM 311 C CA . ASP A 1 46 ? -82.234 -30.407 18.504 1.00 113.23 ? 72 ASP A CA 1 ATOM 312 C C . ASP A 1 46 ? -83.459 -31.284 18.730 1.00 114.77 ? 72 ASP A C 1 ATOM 313 O O . ASP A 1 46 ? -84.383 -30.902 19.456 1.00 117.25 ? 72 ASP A O 1 ATOM 314 C CB . ASP A 1 46 ? -82.333 -29.164 19.407 1.00 125.60 ? 72 ASP A CB 1 ATOM 315 C CG . ASP A 1 46 ? -81.054 -28.333 19.419 1.00 118.76 ? 72 ASP A CG 1 ATOM 316 O OD1 . ASP A 1 46 ? -80.003 -28.826 18.961 1.00 109.36 ? 72 ASP A OD1 1 ATOM 317 O OD2 . ASP A 1 46 ? -81.095 -27.202 19.946 1.00 132.98 ? 72 ASP A OD2 1 ATOM 318 N N . ASN A 1 47 ? -83.442 -32.470 18.128 1.00 118.04 ? 73 ASN A N 1 ATOM 319 C CA . ASN A 1 47 ? -84.529 -33.447 18.255 1.00 110.50 ? 73 ASN A CA 1 ATOM 320 C C . ASN A 1 47 ? -83.980 -34.863 18.439 1.00 128.19 ? 73 ASN A C 1 ATOM 321 O O . ASN A 1 47 ? -82.781 -35.049 18.733 1.00 104.47 ? 73 ASN A O 1 ATOM 322 C CB . ASN A 1 47 ? -85.479 -33.365 17.051 1.00 99.83 ? 73 ASN A CB 1 ATOM 323 C CG . ASN A 1 47 ? -86.356 -32.124 17.084 1.00 101.70 ? 73 ASN A CG 1 ATOM 324 O OD1 . ASN A 1 47 ? -86.798 -31.696 18.155 1.00 93.77 ? 73 ASN A OD1 1 ATOM 325 N ND2 . ASN A 1 47 ? -86.711 -31.612 15.907 1.00 102.77 ? 73 ASN A ND2 1 ATOM 326 N N . PHE A 1 48 ? -84.877 -35.849 18.379 1.00 148.06 ? 74 PHE A N 1 ATOM 327 C CA . PHE A 1 48 ? -84.483 -37.247 18.530 1.00 140.88 ? 74 PHE A CA 1 ATOM 328 C C . PHE A 1 48 ? -84.590 -38.009 17.211 1.00 123.47 ? 74 PHE A C 1 ATOM 329 O O . PHE A 1 48 ? -84.346 -39.216 17.166 1.00 111.82 ? 74 PHE A O 1 ATOM 330 C CB . PHE A 1 48 ? -85.294 -37.943 19.629 1.00 136.82 ? 74 PHE A CB 1 ATOM 331 C CG . PHE A 1 48 ? -85.143 -37.310 20.987 1.00 135.83 ? 74 PHE A CG 1 ATOM 332 C CD1 . PHE A 1 48 ? -83.966 -37.473 21.716 1.00 132.00 ? 74 PHE A CD1 1 ATOM 333 C CD2 . PHE A 1 48 ? -86.212 -36.648 21.585 1.00 121.66 ? 74 PHE A CD2 1 ATOM 334 C CE1 . PHE A 1 48 ? -83.826 -36.903 22.971 1.00 123.98 ? 74 PHE A CE1 1 ATOM 335 C CE2 . PHE A 1 48 ? -86.085 -36.100 22.850 1.00 118.94 ? 74 PHE A CE2 1 ATOM 336 C CZ . PHE A 1 48 ? -84.890 -36.228 23.544 1.00 117.87 ? 74 PHE A CZ 1 ATOM 337 N N . ILE A 1 49 ? -84.917 -37.298 16.134 1.00 103.09 ? 75 ILE A N 1 ATOM 338 C CA . ILE A 1 49 ? -85.023 -37.926 14.826 1.00 95.17 ? 75 ILE A CA 1 ATOM 339 C C . ILE A 1 49 ? -83.808 -38.817 14.590 1.00 105.46 ? 75 ILE A C 1 ATOM 340 O O . ILE A 1 49 ? -82.692 -38.472 14.989 1.00 114.14 ? 75 ILE A O 1 ATOM 341 C CB . ILE A 1 49 ? -85.102 -36.886 13.699 1.00 86.35 ? 75 ILE A CB 1 ATOM 342 C CG1 . ILE A 1 49 ? -86.376 -36.069 13.843 1.00 83.10 ? 75 ILE A CG1 1 ATOM 343 C CG2 . ILE A 1 49 ? -85.088 -37.573 12.337 1.00 89.47 ? 75 ILE A CG2 1 ATOM 344 C CD1 . ILE A 1 49 ? -86.545 -35.017 12.782 1.00 82.94 ? 75 ILE A CD1 1 ATOM 345 N N . THR A 1 50 ? -84.034 -39.980 13.984 1.00 103.71 ? 76 THR A N 1 ATOM 346 C CA . THR A 1 50 ? -82.946 -40.912 13.705 1.00 100.79 ? 76 THR A CA 1 ATOM 347 C C . THR A 1 50 ? -82.974 -41.460 12.289 1.00 101.42 ? 76 THR A C 1 ATOM 348 O O . THR A 1 50 ? -82.012 -42.098 11.835 1.00 86.84 ? 76 THR A O 1 ATOM 349 C CB . THR A 1 50 ? -82.927 -42.081 14.705 1.00 111.70 ? 76 THR A CB 1 ATOM 350 O OG1 . THR A 1 50 ? -81.945 -43.039 14.294 1.00 111.78 ? 76 THR A OG1 1 ATOM 351 C CG2 . THR A 1 50 ? -84.287 -42.769 14.772 1.00 117.73 ? 76 THR A CG2 1 ATOM 352 N N . HIS A 1 51 ? -84.054 -41.192 11.570 1.00 98.04 ? 77 HIS A N 1 ATOM 353 C CA . HIS A 1 51 ? -84.156 -41.676 10.215 1.00 107.65 ? 77 HIS A CA 1 ATOM 354 C C . HIS A 1 51 ? -84.553 -40.624 9.219 1.00 98.88 ? 77 HIS A C 1 ATOM 355 O O . HIS A 1 51 ? -85.525 -39.905 9.411 1.00 86.35 ? 77 HIS A O 1 ATOM 356 C CB . HIS A 1 51 ? -85.141 -42.856 10.099 1.00 128.14 ? 77 HIS A CB 1 ATOM 357 C CG . HIS A 1 51 ? -84.614 -44.149 10.642 1.00 135.22 ? 77 HIS A CG 1 ATOM 358 N ND1 . HIS A 1 51 ? -85.116 -44.755 11.775 1.00 131.68 ? 77 HIS A ND1 1 ATOM 359 C CD2 . HIS A 1 51 ? -83.575 -44.915 10.236 1.00 133.22 ? 77 HIS A CD2 1 ATOM 360 C CE1 . HIS A 1 51 ? -84.448 -45.873 12.004 1.00 131.38 ? 77 HIS A CE1 1 ATOM 361 N NE2 . HIS A 1 51 ? -83.493 -45.980 11.097 1.00 132.74 ? 77 HIS A NE2 1 ATOM 362 N N . ILE A 1 52 ? -83.771 -40.520 8.159 1.00 97.78 ? 78 ILE A N 1 ATOM 363 C CA . ILE A 1 52 ? -84.073 -39.592 7.100 1.00 115.80 ? 78 ILE A CA 1 ATOM 364 C C . ILE A 1 52 ? -84.277 -40.471 5.914 1.00 124.91 ? 78 ILE A C 1 ATOM 365 O O . ILE A 1 52 ? -83.401 -41.271 5.568 1.00 111.08 ? 78 ILE A O 1 ATOM 366 C CB . ILE A 1 52 ? -83.002 -38.523 6.887 1.00 125.01 ? 78 ILE A CB 1 ATOM 367 C CG1 . ILE A 1 52 ? -83.008 -37.579 8.095 1.00 119.41 ? 78 ILE A CG1 1 ATOM 368 C CG2 . ILE A 1 52 ? -83.296 -37.730 5.618 1.00 127.55 ? 78 ILE A CG2 1 ATOM 369 C CD1 . ILE A 1 52 ? -84.377 -36.964 8.377 1.00 112.79 ? 78 ILE A CD1 1 ATOM 370 N N . THR A 1 53 ? -85.427 -40.287 5.271 1.00 133.26 ? 79 THR A N 1 ATOM 371 C CA . THR A 1 53 ? -85.805 -41.120 4.158 1.00 131.95 ? 79 THR A CA 1 ATOM 372 C C . THR A 1 53 ? -86.719 -40.482 3.109 1.00 127.93 ? 79 THR A C 1 ATOM 373 O O . THR A 1 53 ? -87.285 -39.413 3.335 1.00 125.72 ? 79 THR A O 1 ATOM 374 C CB . THR A 1 53 ? -86.522 -42.362 4.732 1.00 130.63 ? 79 THR A CB 1 ATOM 375 O OG1 . THR A 1 53 ? -86.787 -43.299 3.689 1.00 132.99 ? 79 THR A OG1 1 ATOM 376 C CG2 . THR A 1 53 ? -87.827 -41.961 5.442 1.00 123.09 ? 79 THR A CG2 1 ATOM 377 N N . ASN A 1 54 ? -86.826 -41.135 1.943 1.00 126.61 ? 80 ASN A N 1 ATOM 378 C CA . ASN A 1 54 ? -87.718 -40.663 0.865 1.00 118.63 ? 80 ASN A CA 1 ATOM 379 C C . ASN A 1 54 ? -89.062 -40.254 1.422 1.00 117.65 ? 80 ASN A C 1 ATOM 380 O O . ASN A 1 54 ? -89.670 -39.276 0.978 1.00 115.18 ? 80 ASN A O 1 ATOM 381 C CB . ASN A 1 54 ? -87.880 -41.724 -0.228 1.00 115.08 ? 80 ASN A CB 1 ATOM 382 C CG . ASN A 1 54 ? -86.997 -41.467 -1.430 1.00 120.39 ? 80 ASN A CG 1 ATOM 383 O OD1 . ASN A 1 54 ? -86.208 -42.314 -1.848 1.00 119.45 ? 80 ASN A OD1 1 ATOM 384 N ND2 . ASN A 1 54 ? -87.150 -40.279 -2.009 1.00 120.82 ? 80 ASN A ND2 1 ATOM 385 N N . GLU A 1 55 ? -89.554 -41.067 2.343 1.00 114.52 ? 81 GLU A N 1 ATOM 386 C CA . GLU A 1 55 ? -90.797 -40.789 3.024 1.00 138.24 ? 81 GLU A CA 1 ATOM 387 C C . GLU A 1 55 ? -90.685 -39.415 3.664 1.00 133.12 ? 81 GLU A C 1 ATOM 388 O O . GLU A 1 55 ? -91.539 -38.555 3.464 1.00 128.51 ? 81 GLU A O 1 ATOM 389 C CB . GLU A 1 55 ? -90.996 -41.812 4.159 1.00 160.44 ? 81 GLU A CB 1 ATOM 390 C CG . GLU A 1 55 ? -91.942 -41.341 5.267 1.00 159.27 ? 81 GLU A CG 1 ATOM 391 C CD . GLU A 1 55 ? -91.742 -42.096 6.586 1.00 145.60 ? 81 GLU A CD 1 ATOM 392 O OE1 . GLU A 1 55 ? -91.413 -43.309 6.554 1.00 133.59 ? 81 GLU A OE1 1 ATOM 393 O OE2 . GLU A 1 55 ? -91.927 -41.469 7.667 1.00 115.08 ? 81 GLU A OE2 1 ATOM 394 N N . SER A 1 56 ? -89.573 -39.219 4.381 1.00 134.18 ? 82 SER A N 1 ATOM 395 C CA . SER A 1 56 ? -89.275 -37.996 5.144 1.00 114.10 ? 82 SER A CA 1 ATOM 396 C C . SER A 1 56 ? -89.811 -36.680 4.581 1.00 106.31 ? 82 SER A C 1 ATOM 397 O O . SER A 1 56 ? -90.535 -35.957 5.277 1.00 87.38 ? 82 SER A O 1 ATOM 398 C CB . SER A 1 56 ? -87.771 -37.893 5.417 1.00 109.49 ? 82 SER A CB 1 ATOM 399 O OG . SER A 1 56 ? -87.289 -39.049 6.098 1.00 94.72 ? 82 SER A OG 1 ATOM 400 N N . PHE A 1 57 ? -89.445 -36.348 3.349 1.00 105.00 ? 83 PHE A N 1 ATOM 401 C CA . PHE A 1 57 ? -89.915 -35.102 2.742 1.00 118.94 ? 83 PHE A CA 1 ATOM 402 C C . PHE A 1 57 ? -90.672 -35.397 1.462 1.00 135.20 ? 83 PHE A C 1 ATOM 403 O O . PHE A 1 57 ? -90.070 -35.711 0.427 1.00 130.56 ? 83 PHE A O 1 ATOM 404 C CB . PHE A 1 57 ? -88.746 -34.137 2.478 1.00 121.26 ? 83 PHE A CB 1 ATOM 405 C CG . PHE A 1 57 ? -87.955 -33.803 3.717 1.00 115.02 ? 83 PHE A CG 1 ATOM 406 C CD1 . PHE A 1 57 ? -88.393 -32.805 4.598 1.00 109.70 ? 83 PHE A CD1 1 ATOM 407 C CD2 . PHE A 1 57 ? -86.787 -34.505 4.022 1.00 100.77 ? 83 PHE A CD2 1 ATOM 408 C CE1 . PHE A 1 57 ? -87.696 -32.541 5.770 1.00 96.95 ? 83 PHE A CE1 1 ATOM 409 C CE2 . PHE A 1 57 ? -86.087 -34.246 5.189 1.00 94.36 ? 83 PHE A CE2 1 ATOM 410 C CZ . PHE A 1 57 ? -86.544 -33.265 6.064 1.00 104.29 ? 83 PHE A CZ 1 ATOM 411 N N . GLN A 1 58 ? -92.001 -35.322 1.549 1.00 145.45 ? 84 GLN A N 1 ATOM 412 C CA . GLN A 1 58 ? -92.859 -35.583 0.401 1.00 139.55 ? 84 GLN A CA 1 ATOM 413 C C . GLN A 1 58 ? -93.403 -34.374 -0.317 1.00 140.67 ? 84 GLN A C 1 ATOM 414 O O . GLN A 1 58 ? -94.227 -33.625 0.226 1.00 111.67 ? 84 GLN A O 1 ATOM 415 C CB . GLN A 1 58 ? -94.041 -36.453 0.774 1.00 137.32 ? 84 GLN A CB 1 ATOM 416 C CG . GLN A 1 58 ? -93.659 -37.857 1.171 1.00 144.06 ? 84 GLN A CG 1 ATOM 417 C CD . GLN A 1 58 ? -94.840 -38.801 1.120 1.00 134.70 ? 84 GLN A CD 1 ATOM 418 O OE1 . GLN A 1 58 ? -94.661 -40.020 1.082 1.00 113.67 ? 84 GLN A OE1 1 ATOM 419 N NE2 . GLN A 1 58 ? -96.044 -38.247 0.978 1.00 131.73 ? 84 GLN A NE2 1 ATOM 420 N N . GLY A 1 59 ? -92.971 -34.223 -1.565 1.00 146.26 ? 85 GLY A N 1 ATOM 421 C CA . GLY A 1 59 ? -93.417 -33.137 -2.408 1.00 142.33 ? 85 GLY A CA 1 ATOM 422 C C . GLY A 1 59 ? -93.536 -31.811 -1.693 1.00 151.48 ? 85 GLY A C 1 ATOM 423 O O . GLY A 1 59 ? -94.589 -31.169 -1.750 1.00 138.38 ? 85 GLY A O 1 ATOM 424 N N . LEU A 1 60 ? -92.557 -31.499 -0.859 1.00 157.20 ? 86 LEU A N 1 ATOM 425 C CA . LEU A 1 60 ? -92.483 -30.178 -0.272 1.00 145.46 ? 86 LEU A CA 1 ATOM 426 C C . LEU A 1 60 ? -92.135 -29.165 -1.349 1.00 146.59 ? 86 LEU A C 1 ATOM 427 O O . LEU A 1 60 ? -92.678 -28.067 -1.397 1.00 124.31 ? 86 LEU A O 1 ATOM 428 C CB . LEU A 1 60 ? -91.489 -30.163 0.874 1.00 135.11 ? 86 LEU A CB 1 ATOM 429 C CG . LEU A 1 60 ? -91.877 -31.085 2.031 1.00 130.93 ? 86 LEU A CG 1 ATOM 430 C CD1 . LEU A 1 60 ? -93.186 -30.637 2.653 1.00 115.76 ? 86 LEU A CD1 1 ATOM 431 C CD2 . LEU A 1 60 ? -91.949 -32.539 1.589 1.00 129.41 ? 86 LEU A CD2 1 ATOM 432 N N . GLN A 1 61 ? -91.187 -29.539 -2.197 1.00 140.37 ? 87 GLN A N 1 ATOM 433 C CA . GLN A 1 61 ? -90.944 -28.833 -3.437 1.00 143.06 ? 87 GLN A CA 1 ATOM 434 C C . GLN A 1 61 ? -90.434 -27.450 -3.132 1.00 136.62 ? 87 GLN A C 1 ATOM 435 O O . GLN A 1 61 ? -89.352 -27.060 -3.535 1.00 130.30 ? 87 GLN A O 1 ATOM 436 C CB . GLN A 1 61 ? -92.210 -28.762 -4.279 1.00 154.30 ? 87 GLN A CB 1 ATOM 437 C CG . GLN A 1 61 ? -93.194 -29.890 -4.013 1.00 167.28 ? 87 GLN A CG 1 ATOM 438 C CD . GLN A 1 61 ? -94.500 -29.721 -4.768 1.00 164.29 ? 87 GLN A CD 1 ATOM 439 O OE1 . GLN A 1 61 ? -95.151 -28.677 -4.687 1.00 150.23 ? 87 GLN A OE1 1 ATOM 440 N NE2 . GLN A 1 61 ? -94.890 -30.753 -5.510 1.00 161.61 ? 87 GLN A NE2 1 ATOM 441 N N . ASN A 1 62 ? -91.253 -26.714 -2.404 1.00 130.01 ? 88 ASN A N 1 ATOM 442 C CA . ASN A 1 62 ? -90.997 -25.324 -2.096 1.00 127.56 ? 88 ASN A CA 1 ATOM 443 C C . ASN A 1 62 ? -89.754 -25.073 -1.267 1.00 125.02 ? 88 ASN A C 1 ATOM 444 O O . ASN A 1 62 ? -89.095 -24.066 -1.433 1.00 122.01 ? 88 ASN A O 1 ATOM 445 C CB . ASN A 1 62 ? -92.219 -24.702 -1.434 1.00 125.55 ? 88 ASN A CB 1 ATOM 446 C CG . ASN A 1 62 ? -93.266 -24.260 -2.436 1.00 126.00 ? 88 ASN A CG 1 ATOM 447 O OD1 . ASN A 1 62 ? -94.376 -23.906 -2.059 1.00 130.82 ? 88 ASN A OD1 1 ATOM 448 N ND2 . ASN A 1 62 ? -92.919 -24.273 -3.717 1.00 117.43 ? 88 ASN A ND2 1 ATOM 449 N N . LEU A 1 63 ? -89.475 -25.970 -0.338 1.00 122.26 ? 89 LEU A N 1 ATOM 450 C CA . LEU A 1 63 ? -88.364 -25.814 0.597 1.00 117.96 ? 89 LEU A CA 1 ATOM 451 C C . LEU A 1 63 ? -86.989 -25.551 0.007 1.00 117.55 ? 89 LEU A C 1 ATOM 452 O O . LEU A 1 63 ? -86.428 -26.373 -0.734 1.00 96.01 ? 89 LEU A O 1 ATOM 453 C CB . LEU A 1 63 ? -88.245 -26.993 1.552 1.00 109.73 ? 89 LEU A CB 1 ATOM 454 C CG . LEU A 1 63 ? -89.462 -27.311 2.407 1.00 105.01 ? 89 LEU A CG 1 ATOM 455 C CD1 . LEU A 1 63 ? -88.958 -28.162 3.560 1.00 97.25 ? 89 LEU A CD1 1 ATOM 456 C CD2 . LEU A 1 63 ? -90.131 -26.059 2.956 1.00 99.58 ? 89 LEU A CD2 1 ATOM 457 N N . THR A 1 64 ? -86.405 -24.460 0.497 1.00 112.38 ? 90 THR A N 1 ATOM 458 C CA . THR A 1 64 ? -85.094 -24.001 0.097 1.00 106.27 ? 90 THR A CA 1 ATOM 459 C C . THR A 1 64 ? -84.028 -24.315 1.155 1.00 107.44 ? 90 THR A C 1 ATOM 460 O O . THR A 1 64 ? -82.876 -24.599 0.806 1.00 100.36 ? 90 THR A O 1 ATOM 461 C CB . THR A 1 64 ? -85.121 -22.490 -0.170 1.00 98.77 ? 90 THR A CB 1 ATOM 462 O OG1 . THR A 1 64 ? -85.640 -21.820 0.979 1.00 97.46 ? 90 THR A OG1 1 ATOM 463 C CG2 . THR A 1 64 ? -86.013 -22.164 -1.359 1.00 94.99 ? 90 THR A CG2 1 ATOM 464 N N . LYS A 1 65 ? -84.412 -24.268 2.434 1.00 101.21 ? 91 LYS A N 1 ATOM 465 C CA . LYS A 1 65 ? -83.482 -24.542 3.542 1.00 110.39 ? 91 LYS A CA 1 ATOM 466 C C . LYS A 1 65 ? -83.995 -25.589 4.531 1.00 105.26 ? 91 LYS A C 1 ATOM 467 O O . LYS A 1 65 ? -85.166 -25.576 4.915 1.00 86.83 ? 91 LYS A O 1 ATOM 468 C CB . LYS A 1 65 ? -83.180 -23.269 4.361 1.00 125.73 ? 91 LYS A CB 1 ATOM 469 C CG . LYS A 1 65 ? -82.369 -22.149 3.709 1.00 151.12 ? 91 LYS A CG 1 ATOM 470 C CD . LYS A 1 65 ? -82.996 -21.458 2.506 1.00 151.43 ? 91 LYS A CD 1 ATOM 471 C CE . LYS A 1 65 ? -82.062 -20.364 1.997 1.00 132.35 ? 91 LYS A CE 1 ATOM 472 N NZ . LYS A 1 65 ? -82.580 -19.674 0.791 1.00 139.26 ? 91 LYS A NZ 1 ATOM 473 N N . ILE A 1 66 ? -83.075 -26.422 5.023 1.00 111.15 ? 92 ILE A N 1 ATOM 474 C CA . ILE A 1 66 ? -83.402 -27.458 6.005 1.00 111.49 ? 92 ILE A CA 1 ATOM 475 C C . ILE A 1 66 ? -82.295 -27.600 7.040 1.00 101.41 ? 92 ILE A C 1 ATOM 476 O O . ILE A 1 66 ? -81.130 -27.842 6.689 1.00 90.23 ? 92 ILE A O 1 ATOM 477 C CB . ILE A 1 66 ? -83.573 -28.844 5.367 1.00 129.80 ? 92 ILE A CB 1 ATOM 478 C CG1 . ILE A 1 66 ? -84.690 -28.829 4.322 1.00 140.31 ? 92 ILE A CG1 1 ATOM 479 C CG2 . ILE A 1 66 ? -83.899 -29.863 6.451 1.00 129.99 ? 92 ILE A CG2 1 ATOM 480 C CD1 . ILE A 1 66 ? -84.846 -30.142 3.581 1.00 136.79 ? 92 ILE A CD1 1 ATOM 481 N N . ASN A 1 67 ? -82.685 -27.536 8.314 1.00 84.47 ? 93 ASN A N 1 ATOM 482 C CA . ASN A 1 67 ? -81.752 -27.666 9.420 1.00 77.80 ? 93 ASN A CA 1 ATOM 483 C C . ASN A 1 67 ? -82.078 -28.928 10.250 1.00 90.27 ? 93 ASN A C 1 ATOM 484 O O . ASN A 1 67 ? -83.137 -29.018 10.889 1.00 84.22 ? 93 ASN A O 1 ATOM 485 C CB . ASN A 1 67 ? -81.846 -26.412 10.301 1.00 79.61 ? 93 ASN A CB 1 ATOM 486 C CG . ASN A 1 67 ? -80.756 -26.339 11.386 1.00 80.52 ? 93 ASN A CG 1 ATOM 487 O OD1 . ASN A 1 67 ? -79.908 -27.237 11.541 1.00 75.75 ? 93 ASN A OD1 1 ATOM 488 N ND2 . ASN A 1 67 ? -80.775 -25.242 12.139 1.00 73.57 ? 93 ASN A ND2 1 ATOM 489 N N . LEU A 1 68 ? -81.150 -29.879 10.255 1.00 85.87 ? 94 LEU A N 1 ATOM 490 C CA . LEU A 1 68 ? -81.302 -31.138 10.996 1.00 99.91 ? 94 LEU A CA 1 ATOM 491 C C . LEU A 1 68 ? -80.131 -31.348 11.959 1.00 107.16 ? 94 LEU A C 1 ATOM 492 O O . LEU A 1 68 ? -79.729 -32.483 12.241 1.00 105.44 ? 94 LEU A O 1 ATOM 493 C CB . LEU A 1 68 ? -81.321 -32.303 10.003 1.00 109.10 ? 94 LEU A CB 1 ATOM 494 C CG . LEU A 1 68 ? -82.478 -32.328 9.006 1.00 116.99 ? 94 LEU A CG 1 ATOM 495 C CD1 . LEU A 1 68 ? -82.194 -33.296 7.870 1.00 113.15 ? 94 LEU A CD1 1 ATOM 496 C CD2 . LEU A 1 68 ? -83.792 -32.650 9.708 1.00 120.27 ? 94 LEU A CD2 1 ATOM 497 N N . ASN A 1 69 ? -79.577 -30.263 12.468 1.00 102.74 ? 95 ASN A N 1 ATOM 498 C CA . ASN A 1 69 ? -78.444 -30.376 13.357 1.00 94.49 ? 95 ASN A CA 1 ATOM 499 C C . ASN A 1 69 ? -78.830 -30.886 14.721 1.00 93.74 ? 95 ASN A C 1 ATOM 500 O O . ASN A 1 69 ? -79.966 -30.717 15.168 1.00 86.49 ? 95 ASN A O 1 ATOM 501 C CB . ASN A 1 69 ? -77.741 -29.033 13.462 1.00 94.87 ? 95 ASN A CB 1 ATOM 502 C CG . ASN A 1 69 ? -77.195 -28.569 12.134 1.00 90.81 ? 95 ASN A CG 1 ATOM 503 O OD1 . ASN A 1 69 ? -76.785 -29.378 11.296 1.00 89.88 ? 95 ASN A OD1 1 ATOM 504 N ND2 . ASN A 1 69 ? -77.166 -27.268 11.941 1.00 82.24 ? 95 ASN A ND2 1 ATOM 505 N N . HIS A 1 70 ? -77.870 -31.539 15.363 1.00 87.89 ? 96 HIS A N 1 ATOM 506 C CA . HIS A 1 70 ? -78.057 -32.095 16.684 1.00 100.80 ? 96 HIS A CA 1 ATOM 507 C C . HIS A 1 70 ? -79.195 -33.118 16.687 1.00 100.26 ? 96 HIS A C 1 ATOM 508 O O . HIS A 1 70 ? -80.225 -32.895 17.315 1.00 91.14 ? 96 HIS A O 1 ATOM 509 C CB . HIS A 1 70 ? -78.344 -30.998 17.726 1.00 105.20 ? 96 HIS A CB 1 ATOM 510 C CG . HIS A 1 70 ? -77.328 -29.895 17.755 1.00 117.14 ? 96 HIS A CG 1 ATOM 511 N ND1 . HIS A 1 70 ? -76.101 -30.027 18.371 1.00 122.70 ? 96 HIS A ND1 1 ATOM 512 C CD2 . HIS A 1 70 ? -77.405 -28.605 17.347 1.00 110.76 ? 96 HIS A CD2 1 ATOM 513 C CE1 . HIS A 1 70 ? -75.434 -28.892 18.265 1.00 113.68 ? 96 HIS A CE1 1 ATOM 514 N NE2 . HIS A 1 70 ? -76.209 -28.009 17.659 1.00 110.86 ? 96 HIS A NE2 1 ATOM 515 N N . ASN A 1 71 ? -79.047 -34.170 15.883 1.00 101.10 ? 97 ASN A N 1 ATOM 516 C CA . ASN A 1 71 ? -80.025 -35.267 15.811 1.00 99.35 ? 97 ASN A CA 1 ATOM 517 C C . ASN A 1 71 ? -79.314 -36.604 15.813 1.00 106.23 ? 97 ASN A C 1 ATOM 518 O O . ASN A 1 71 ? -78.543 -36.895 14.902 1.00 119.21 ? 97 ASN A O 1 ATOM 519 C CB . ASN A 1 71 ? -80.957 -35.172 14.603 1.00 87.84 ? 97 ASN A CB 1 ATOM 520 C CG . ASN A 1 71 ? -82.035 -34.121 14.778 1.00 89.96 ? 97 ASN A CG 1 ATOM 521 O OD1 . ASN A 1 71 ? -82.084 -33.430 15.783 1.00 99.52 ? 97 ASN A OD1 1 ATOM 522 N ND2 . ASN A 1 71 ? -82.944 -34.046 13.825 1.00 101.32 ? 97 ASN A ND2 1 ATOM 523 N N . PRO A 1 72 ? -79.538 -37.408 16.851 1.00 118.22 ? 98 PRO A N 1 ATOM 524 C CA . PRO A 1 72 ? -80.421 -37.068 17.964 1.00 102.15 ? 98 PRO A CA 1 ATOM 525 C C . PRO A 1 72 ? -79.625 -36.682 19.203 1.00 108.84 ? 98 PRO A C 1 ATOM 526 O O . PRO A 1 72 ? -78.448 -37.038 19.304 1.00 122.49 ? 98 PRO A O 1 ATOM 527 C CB . PRO A 1 72 ? -81.131 -38.380 18.217 1.00 111.70 ? 98 PRO A CB 1 ATOM 528 C CG . PRO A 1 72 ? -80.077 -39.405 17.941 1.00 109.63 ? 98 PRO A CG 1 ATOM 529 C CD . PRO A 1 72 ? -79.256 -38.855 16.807 1.00 117.06 ? 98 PRO A CD 1 ATOM 530 N N . ASN A 1 73 ? -80.276 -36.042 20.173 1.00 114.27 ? 99 ASN A N 1 ATOM 531 C CA . ASN A 1 73 ? -79.596 -35.622 21.412 1.00 123.49 ? 99 ASN A CA 1 ATOM 532 C C . ASN A 1 73 ? -79.371 -36.769 22.408 1.00 131.86 ? 99 ASN A C 1 ATOM 533 O O . ASN A 1 73 ? -80.158 -36.962 23.338 1.00 133.75 ? 99 ASN A O 1 ATOM 534 C CB . ASN A 1 73 ? -80.383 -34.493 22.084 1.00 123.62 ? 99 ASN A CB 1 ATOM 535 C CG . ASN A 1 73 ? -80.528 -33.267 21.196 1.00 121.94 ? 99 ASN A CG 1 ATOM 536 O OD1 . ASN A 1 73 ? -81.401 -32.430 21.420 1.00 106.47 ? 99 ASN A OD1 1 ATOM 537 N ND2 . ASN A 1 73 ? -79.716 -33.184 20.150 1.00 126.96 ? 99 ASN A ND2 1 ATOM 538 N N . VAL A 1 74 ? -78.282 -37.515 22.215 1.00 138.11 ? 100 VAL A N 1 ATOM 539 C CA . VAL A 1 74 ? -77.945 -38.642 23.097 1.00 145.42 ? 100 VAL A CA 1 ATOM 540 C C . VAL A 1 74 ? -77.275 -38.136 24.373 1.00 138.49 ? 100 VAL A C 1 ATOM 541 O O . VAL A 1 74 ? -77.865 -37.366 25.128 1.00 117.50 ? 100 VAL A O 1 ATOM 542 C CB . VAL A 1 74 ? -77.025 -39.684 22.400 1.00 139.91 ? 100 VAL A CB 1 ATOM 543 C CG1 . VAL A 1 74 ? -75.690 -39.067 21.992 1.00 133.86 ? 100 VAL A CG1 1 ATOM 544 C CG2 . VAL A 1 74 ? -76.812 -40.899 23.300 1.00 132.83 ? 100 VAL A CG2 1 ATOM 545 N N . GLY A 1 87 ? -76.084 -41.729 16.197 1.00 107.22 ? 113 GLY A N 1 ATOM 546 C CA . GLY A 1 87 ? -75.983 -41.434 14.769 1.00 101.93 ? 113 GLY A CA 1 ATOM 547 C C . GLY A 1 87 ? -77.312 -41.074 14.129 1.00 108.73 ? 113 GLY A C 1 ATOM 548 O O . GLY A 1 87 ? -78.347 -41.069 14.793 1.00 115.26 ? 113 GLY A O 1 ATOM 549 N N . LEU A 1 88 ? -77.260 -40.699 12.850 1.00 105.82 ? 114 LEU A N 1 ATOM 550 C CA . LEU A 1 88 ? -78.454 -40.339 12.071 1.00 98.01 ? 114 LEU A CA 1 ATOM 551 C C . LEU A 1 88 ? -78.399 -41.133 10.791 1.00 98.89 ? 114 LEU A C 1 ATOM 552 O O . LEU A 1 88 ? -77.352 -41.189 10.143 1.00 79.68 ? 114 LEU A O 1 ATOM 553 C CB . LEU A 1 88 ? -78.485 -38.847 11.727 1.00 101.38 ? 114 LEU A CB 1 ATOM 554 C CG . LEU A 1 88 ? -79.665 -38.372 10.857 1.00 101.45 ? 114 LEU A CG 1 ATOM 555 C CD1 . LEU A 1 88 ? -81.005 -38.591 11.539 1.00 96.16 ? 114 LEU A CD1 1 ATOM 556 C CD2 . LEU A 1 88 ? -79.520 -36.904 10.502 1.00 101.82 ? 114 LEU A CD2 1 ATOM 557 N N . ASN A 1 89 ? -79.526 -41.744 10.431 1.00 112.21 ? 115 ASN A N 1 ATOM 558 C CA . ASN A 1 89 ? -79.623 -42.560 9.226 1.00 114.90 ? 115 ASN A CA 1 ATOM 559 C C . ASN A 1 89 ? -80.288 -41.787 8.106 1.00 106.76 ? 115 ASN A C 1 ATOM 560 O O . ASN A 1 89 ? -81.413 -41.309 8.261 1.00 96.80 ? 115 ASN A O 1 ATOM 561 C CB . ASN A 1 89 ? -80.413 -43.842 9.531 1.00 123.92 ? 115 ASN A CB 1 ATOM 562 C CG . ASN A 1 89 ? -80.587 -44.741 8.312 1.00 132.00 ? 115 ASN A CG 1 ATOM 563 O OD1 . ASN A 1 89 ? -80.244 -44.366 7.196 1.00 130.47 ? 115 ASN A OD1 1 ATOM 564 N ND2 . ASN A 1 89 ? -81.152 -45.927 8.523 1.00 141.50 ? 115 ASN A ND2 1 ATOM 565 N N . ILE A 1 90 ? -79.602 -41.705 6.965 1.00 104.95 ? 116 ILE A N 1 ATOM 566 C CA . ILE A 1 90 ? -80.115 -40.987 5.801 1.00 114.95 ? 116 ILE A CA 1 ATOM 567 C C . ILE A 1 90 ? -80.155 -41.836 4.522 1.00 123.14 ? 116 ILE A C 1 ATOM 568 O O . ILE A 1 90 ? -79.147 -42.424 4.099 1.00 101.53 ? 116 ILE A O 1 ATOM 569 C CB . ILE A 1 90 ? -79.284 -39.718 5.533 1.00 119.26 ? 116 ILE A CB 1 ATOM 570 C CG1 . ILE A 1 90 ? -79.346 -38.797 6.756 1.00 123.84 ? 116 ILE A CG1 1 ATOM 571 C CG2 . ILE A 1 90 ? -79.803 -38.993 4.294 1.00 118.98 ? 116 ILE A CG2 1 ATOM 572 C CD1 . ILE A 1 90 ? -78.493 -37.554 6.650 1.00 120.99 ? 116 ILE A CD1 1 ATOM 573 N N . THR A 1 91 ? -81.317 -41.820 3.873 1.00 130.20 ? 117 THR A N 1 ATOM 574 C CA . THR A 1 91 ? -81.542 -42.568 2.630 1.00 131.22 ? 117 THR A CA 1 ATOM 575 C C . THR A 1 91 ? -81.070 -41.830 1.374 1.00 129.95 ? 117 THR A C 1 ATOM 576 O O . THR A 1 91 ? -81.475 -40.695 1.091 1.00 101.39 ? 117 THR A O 1 ATOM 577 C CB . THR A 1 91 ? -83.013 -43.004 2.491 1.00 128.65 ? 117 THR A CB 1 ATOM 578 O OG1 . THR A 1 91 ? -83.291 -43.356 1.127 1.00 140.87 ? 117 THR A OG1 1 ATOM 579 C CG2 . THR A 1 91 ? -83.898 -41.911 2.854 1.00 128.03 ? 117 THR A CG2 1 ATOM 580 N N . ASP A 1 92 ? -80.252 -42.534 0.597 1.00 119.70 ? 118 ASP A N 1 ATOM 581 C CA . ASP A 1 92 ? -79.671 -42.009 -0.639 1.00 112.08 ? 118 ASP A CA 1 ATOM 582 C C . ASP A 1 92 ? -80.736 -41.400 -1.517 1.00 108.81 ? 118 ASP A C 1 ATOM 583 O O . ASP A 1 92 ? -81.752 -42.023 -1.776 1.00 134.27 ? 118 ASP A O 1 ATOM 584 C CB . ASP A 1 92 ? -78.971 -43.129 -1.378 1.00 97.49 ? 118 ASP A CB 1 ATOM 585 C CG . ASP A 1 92 ? -78.075 -43.942 -0.457 1.00 113.76 ? 118 ASP A CG 1 ATOM 586 O OD1 . ASP A 1 92 ? -78.332 -43.907 0.775 1.00 105.78 ? 118 ASP A OD1 1 ATOM 587 O OD2 . ASP A 1 92 ? -77.188 -44.675 -0.954 1.00 98.64 ? 118 ASP A OD2 1 ATOM 588 N N . GLY A 1 93 ? -80.498 -40.178 -1.974 1.00 102.80 ? 119 GLY A N 1 ATOM 589 C CA . GLY A 1 93 ? -81.464 -39.475 -2.809 1.00 107.86 ? 119 GLY A CA 1 ATOM 590 C C . GLY A 1 93 ? -82.662 -38.969 -2.003 1.00 116.52 ? 119 GLY A C 1 ATOM 591 O O . GLY A 1 93 ? -83.646 -38.499 -2.573 1.00 129.30 ? 119 GLY A O 1 ATOM 592 N N . ALA A 1 94 ? -82.548 -38.991 -0.677 1.00 103.82 ? 120 ALA A N 1 ATOM 593 C CA . ALA A 1 94 ? -83.630 -38.553 0.206 1.00 102.98 ? 120 ALA A CA 1 ATOM 594 C C . ALA A 1 94 ? -84.168 -37.152 -0.034 1.00 110.49 ? 120 ALA A C 1 ATOM 595 O O . ALA A 1 94 ? -85.357 -36.907 0.153 1.00 129.58 ? 120 ALA A O 1 ATOM 596 C CB . ALA A 1 94 ? -83.180 -38.648 1.648 1.00 114.95 ? 120 ALA A CB 1 ATOM 597 N N . PHE A 1 95 ? -83.301 -36.226 -0.423 1.00 114.36 ? 121 PHE A N 1 ATOM 598 C CA . PHE A 1 95 ? -83.725 -34.836 -0.619 1.00 110.40 ? 121 PHE A CA 1 ATOM 599 C C . PHE A 1 95 ? -84.045 -34.434 -2.060 1.00 111.70 ? 121 PHE A C 1 ATOM 600 O O . PHE A 1 95 ? -84.679 -33.398 -2.288 1.00 114.40 ? 121 PHE A O 1 ATOM 601 C CB . PHE A 1 95 ? -82.635 -33.895 -0.081 1.00 106.62 ? 121 PHE A CB 1 ATOM 602 C CG . PHE A 1 95 ? -82.241 -34.161 1.355 1.00 79.45 ? 121 PHE A CG 1 ATOM 603 C CD1 . PHE A 1 95 ? -82.970 -33.621 2.397 1.00 74.41 ? 121 PHE A CD1 1 ATOM 604 C CD2 . PHE A 1 95 ? -81.087 -34.877 1.652 1.00 73.20 ? 121 PHE A CD2 1 ATOM 605 C CE1 . PHE A 1 95 ? -82.602 -33.857 3.719 1.00 78.17 ? 121 PHE A CE1 1 ATOM 606 C CE2 . PHE A 1 95 ? -80.702 -35.101 2.967 1.00 76.27 ? 121 PHE A CE2 1 ATOM 607 C CZ . PHE A 1 95 ? -81.461 -34.588 4.004 1.00 71.82 ? 121 PHE A CZ 1 ATOM 608 N N . LEU A 1 96 ? -83.675 -35.276 -3.018 1.00 104.87 ? 122 LEU A N 1 ATOM 609 C CA . LEU A 1 96 ? -83.892 -34.980 -4.451 1.00 104.90 ? 122 LEU A CA 1 ATOM 610 C C . LEU A 1 96 ? -85.308 -34.535 -4.807 1.00 105.56 ? 122 LEU A C 1 ATOM 611 O O . LEU A 1 96 ? -85.497 -33.762 -5.740 1.00 105.68 ? 122 LEU A O 1 ATOM 612 C CB . LEU A 1 96 ? -83.464 -36.169 -5.305 1.00 93.09 ? 122 LEU A CB 1 ATOM 613 C CG . LEU A 1 96 ? -81.952 -36.445 -5.318 1.00 105.95 ? 122 LEU A CG 1 ATOM 614 C CD1 . LEU A 1 96 ? -81.264 -36.218 -3.972 1.00 109.45 ? 122 LEU A CD1 1 ATOM 615 C CD2 . LEU A 1 96 ? -81.674 -37.843 -5.857 1.00 97.30 ? 122 LEU A CD2 1 ATOM 616 N N . ASN A 1 97 ? -86.299 -35.005 -4.060 1.00 124.64 ? 123 ASN A N 1 ATOM 617 C CA . ASN A 1 97 ? -87.682 -34.619 -4.323 1.00 143.45 ? 123 ASN A CA 1 ATOM 618 C C . ASN A 1 97 ? -87.813 -33.095 -4.223 1.00 142.15 ? 123 ASN A C 1 ATOM 619 O O . ASN A 1 97 ? -88.756 -32.498 -4.764 1.00 116.04 ? 123 ASN A O 1 ATOM 620 C CB . ASN A 1 97 ? -88.634 -35.306 -3.320 1.00 154.80 ? 123 ASN A CB 1 ATOM 621 C CG . ASN A 1 97 ? -90.113 -34.993 -3.575 1.00 159.87 ? 123 ASN A CG 1 ATOM 622 O OD1 . ASN A 1 97 ? -90.982 -35.454 -2.834 1.00 150.01 ? 123 ASN A OD1 1 ATOM 623 N ND2 . ASN A 1 97 ? -90.404 -34.222 -4.620 1.00 165.64 ? 123 ASN A ND2 1 ATOM 624 N N . LEU A 1 98 ? -86.867 -32.469 -3.525 1.00 146.18 ? 124 LEU A N 1 ATOM 625 C CA . LEU A 1 98 ? -86.887 -31.030 -3.352 1.00 142.01 ? 124 LEU A CA 1 ATOM 626 C C . LEU A 1 98 ? -85.751 -30.517 -4.226 1.00 136.07 ? 124 LEU A C 1 ATOM 627 O O . LEU A 1 98 ? -84.581 -30.824 -3.984 1.00 132.92 ? 124 LEU A O 1 ATOM 628 C CB . LEU A 1 98 ? -86.580 -30.661 -1.906 1.00 133.43 ? 124 LEU A CB 1 ATOM 629 C CG . LEU A 1 98 ? -86.968 -31.672 -0.818 1.00 137.50 ? 124 LEU A CG 1 ATOM 630 C CD1 . LEU A 1 98 ? -86.795 -31.056 0.559 1.00 139.80 ? 124 LEU A CD1 1 ATOM 631 C CD2 . LEU A 1 98 ? -88.338 -32.316 -0.974 1.00 151.11 ? 124 LEU A CD2 1 ATOM 632 N N . LYS A 1 99 ? -86.094 -29.816 -5.290 1.00 126.12 ? 125 LYS A N 1 ATOM 633 C CA . LYS A 1 99 ? -85.093 -29.271 -6.186 1.00 136.35 ? 125 LYS A CA 1 ATOM 634 C C . LYS A 1 99 ? -85.013 -27.737 -6.058 1.00 127.57 ? 125 LYS A C 1 ATOM 635 O O . LYS A 1 99 ? -84.509 -27.042 -6.935 1.00 112.60 ? 125 LYS A O 1 ATOM 636 C CB . LYS A 1 99 ? -85.316 -29.773 -7.621 1.00 142.71 ? 125 LYS A CB 1 ATOM 637 C CG . LYS A 1 99 ? -84.671 -28.905 -8.689 1.00 155.26 ? 125 LYS A CG 1 ATOM 638 C CD . LYS A 1 99 ? -83.158 -28.783 -8.629 1.00 139.57 ? 125 LYS A CD 1 ATOM 639 C CE . LYS A 1 99 ? -82.731 -27.496 -9.343 1.00 135.36 ? 125 LYS A CE 1 ATOM 640 N NZ . LYS A 1 99 ? -83.382 -27.281 -10.669 1.00 126.70 ? 125 LYS A NZ 1 ATOM 641 N N . ASN A 1 100 ? -85.570 -27.217 -4.973 1.00 127.74 ? 126 ASN A N 1 ATOM 642 C CA . ASN A 1 100 ? -85.504 -25.791 -4.685 1.00 125.49 ? 126 ASN A CA 1 ATOM 643 C C . ASN A 1 100 ? -84.788 -25.682 -3.365 1.00 124.70 ? 126 ASN A C 1 ATOM 644 O O . ASN A 1 100 ? -84.881 -24.673 -2.672 1.00 114.84 ? 126 ASN A O 1 ATOM 645 C CB . ASN A 1 100 ? -86.882 -25.162 -4.592 1.00 120.59 ? 126 ASN A CB 1 ATOM 646 C CG . ASN A 1 100 ? -87.630 -25.251 -5.885 1.00 114.16 ? 126 ASN A CG 1 ATOM 647 O OD1 . ASN A 1 100 ? -87.290 -26.060 -6.737 1.00 110.96 ? 126 ASN A OD1 1 ATOM 648 N ND2 . ASN A 1 100 ? -88.657 -24.424 -6.045 1.00 111.83 ? 126 ASN A ND2 1 ATOM 649 N N . LEU A 1 101 ? -84.066 -26.751 -3.035 1.00 122.49 ? 127 LEU A N 1 ATOM 650 C CA . LEU A 1 101 ? -83.323 -26.846 -1.799 1.00 114.13 ? 127 LEU A CA 1 ATOM 651 C C . LEU A 1 101 ? -81.950 -26.261 -2.054 1.00 114.17 ? 127 LEU A C 1 ATOM 652 O O . LEU A 1 101 ? -81.185 -26.771 -2.891 1.00 88.98 ? 127 LEU A O 1 ATOM 653 C CB . LEU A 1 101 ? -83.192 -28.313 -1.367 1.00 101.40 ? 127 LEU A CB 1 ATOM 654 C CG . LEU A 1 101 ? -82.602 -28.583 0.019 1.00 89.31 ? 127 LEU A CG 1 ATOM 655 C CD1 . LEU A 1 101 ? -83.548 -28.089 1.097 1.00 80.77 ? 127 LEU A CD1 1 ATOM 656 C CD2 . LEU A 1 101 ? -82.334 -30.062 0.225 1.00 87.89 ? 127 LEU A CD2 1 ATOM 657 N N . ARG A 1 102 ? -81.655 -25.172 -1.352 1.00 109.51 ? 128 ARG A N 1 ATOM 658 C CA . ARG A 1 102 ? -80.383 -24.503 -1.495 1.00 109.81 ? 128 ARG A CA 1 ATOM 659 C C . ARG A 1 102 ? -79.492 -24.627 -0.263 1.00 96.24 ? 128 ARG A C 1 ATOM 660 O O . ARG A 1 102 ? -78.288 -24.809 -0.394 1.00 91.43 ? 128 ARG A O 1 ATOM 661 C CB . ARG A 1 102 ? -80.611 -23.047 -1.893 1.00 110.54 ? 128 ARG A CB 1 ATOM 662 C CG . ARG A 1 102 ? -81.247 -22.920 -3.271 1.00 112.02 ? 128 ARG A CG 1 ATOM 663 C CD . ARG A 1 102 ? -81.453 -21.481 -3.705 1.00 115.63 ? 128 ARG A CD 1 ATOM 664 N NE . ARG A 1 102 ? -82.377 -20.760 -2.834 1.00 121.68 ? 128 ARG A NE 1 ATOM 665 C CZ . ARG A 1 102 ? -82.748 -19.494 -3.021 1.00 139.70 ? 128 ARG A CZ 1 ATOM 666 N NH1 . ARG A 1 102 ? -82.271 -18.798 -4.051 1.00 140.64 ? 128 ARG A NH1 1 ATOM 667 N NH2 . ARG A 1 102 ? -83.604 -18.921 -2.181 1.00 144.80 ? 128 ARG A NH2 1 ATOM 668 N N . GLU A 1 103 ? -80.088 -24.644 0.923 1.00 91.99 ? 129 GLU A N 1 ATOM 669 C CA . GLU A 1 103 ? -79.301 -24.742 2.150 1.00 94.46 ? 129 GLU A CA 1 ATOM 670 C C . GLU A 1 103 ? -79.637 -26.003 2.957 1.00 90.04 ? 129 GLU A C 1 ATOM 671 O O . GLU A 1 103 ? -80.779 -26.209 3.359 1.00 88.18 ? 129 GLU A O 1 ATOM 672 C CB . GLU A 1 103 ? -79.546 -23.482 3.001 1.00 100.16 ? 129 GLU A CB 1 ATOM 673 C CG . GLU A 1 103 ? -78.666 -23.302 4.238 1.00 99.90 ? 129 GLU A CG 1 ATOM 674 C CD . GLU A 1 103 ? -78.926 -21.982 4.970 1.00 99.85 ? 129 GLU A CD 1 ATOM 675 O OE1 . GLU A 1 103 ? -79.790 -21.207 4.531 1.00 108.66 ? 129 GLU A OE1 1 ATOM 676 O OE2 . GLU A 1 103 ? -78.259 -21.701 5.984 1.00 100.19 ? 129 GLU A OE2 1 ATOM 677 N N . LEU A 1 104 ? -78.636 -26.846 3.194 1.00 86.69 ? 130 LEU A N 1 ATOM 678 C CA . LEU A 1 104 ? -78.845 -28.051 3.976 1.00 80.06 ? 130 LEU A CA 1 ATOM 679 C C . LEU A 1 104 ? -77.850 -28.143 5.122 1.00 74.96 ? 130 LEU A C 1 ATOM 680 O O . LEU A 1 104 ? -76.641 -28.294 4.901 1.00 76.40 ? 130 LEU A O 1 ATOM 681 C CB . LEU A 1 104 ? -78.724 -29.306 3.117 1.00 92.83 ? 130 LEU A CB 1 ATOM 682 C CG . LEU A 1 104 ? -78.965 -30.595 3.930 1.00 92.80 ? 130 LEU A CG 1 ATOM 683 C CD1 . LEU A 1 104 ? -80.368 -30.601 4.543 1.00 82.70 ? 130 LEU A CD1 1 ATOM 684 C CD2 . LEU A 1 104 ? -78.737 -31.831 3.076 1.00 89.81 ? 130 LEU A CD2 1 ATOM 685 N N . LEU A 1 105 ? -78.372 -28.172 6.346 1.00 69.45 ? 131 LEU A N 1 ATOM 686 C CA . LEU A 1 105 ? -77.523 -28.255 7.533 1.00 74.91 ? 131 LEU A CA 1 ATOM 687 C C . LEU A 1 105 ? -77.601 -29.606 8.271 1.00 71.81 ? 131 LEU A C 1 ATOM 688 O O . LEU A 1 105 ? -78.595 -29.917 8.911 1.00 76.08 ? 131 LEU A O 1 ATOM 689 C CB . LEU A 1 105 ? -77.885 -27.126 8.495 1.00 77.27 ? 131 LEU A CB 1 ATOM 690 C CG . LEU A 1 105 ? -77.833 -25.715 7.899 1.00 80.75 ? 131 LEU A CG 1 ATOM 691 C CD1 . LEU A 1 105 ? -78.226 -24.693 8.954 1.00 73.78 ? 131 LEU A CD1 1 ATOM 692 C CD2 . LEU A 1 105 ? -76.456 -25.403 7.321 1.00 87.48 ? 131 LEU A CD2 1 ATOM 693 N N . LEU A 1 106 ? -76.486 -30.326 8.274 1.00 68.95 ? 132 LEU A N 1 ATOM 694 C CA . LEU A 1 106 ? -76.369 -31.627 8.910 1.00 63.74 ? 132 LEU A CA 1 ATOM 695 C C . LEU A 1 106 ? -75.188 -31.647 9.851 1.00 71.60 ? 132 LEU A C 1 ATOM 696 O O . LEU A 1 106 ? -74.205 -32.366 9.630 1.00 82.24 ? 132 LEU A O 1 ATOM 697 C CB . LEU A 1 106 ? -76.151 -32.685 7.837 1.00 78.33 ? 132 LEU A CB 1 ATOM 698 C CG . LEU A 1 106 ? -77.294 -32.796 6.821 1.00 89.74 ? 132 LEU A CG 1 ATOM 699 C CD1 . LEU A 1 106 ? -76.903 -33.756 5.708 1.00 91.06 ? 132 LEU A CD1 1 ATOM 700 C CD2 . LEU A 1 106 ? -78.591 -33.222 7.500 1.00 81.82 ? 132 LEU A CD2 1 ATOM 701 N N . GLU A 1 107 ? -75.305 -30.907 10.939 1.00 75.05 ? 133 GLU A N 1 ATOM 702 C CA . GLU A 1 107 ? -74.225 -30.816 11.896 1.00 77.40 ? 133 GLU A CA 1 ATOM 703 C C . GLU A 1 107 ? -74.553 -31.576 13.144 1.00 76.98 ? 133 GLU A C 1 ATOM 704 O O . GLU A 1 107 ? -75.713 -31.631 13.572 1.00 68.90 ? 133 GLU A O 1 ATOM 705 C CB . GLU A 1 107 ? -73.963 -29.341 12.276 1.00 85.42 ? 133 GLU A CB 1 ATOM 706 C CG . GLU A 1 107 ? -73.647 -28.430 11.098 1.00 95.37 ? 133 GLU A CG 1 ATOM 707 C CD . GLU A 1 107 ? -73.484 -26.965 11.479 1.00 90.86 ? 133 GLU A CD 1 ATOM 708 O OE1 . GLU A 1 107 ? -73.233 -26.668 12.667 1.00 92.38 ? 133 GLU A OE1 1 ATOM 709 O OE2 . GLU A 1 107 ? -73.601 -26.111 10.568 1.00 69.80 ? 133 GLU A OE2 1 ATOM 710 N N . ASP A 1 108 ? -73.536 -32.160 13.750 1.00 83.11 ? 134 ASP A N 1 ATOM 711 C CA . ASP A 1 108 ? -73.706 -32.909 14.973 1.00 90.40 ? 134 ASP A CA 1 ATOM 712 C C . ASP A 1 108 ? -74.714 -34.015 14.781 1.00 96.10 ? 134 ASP A C 1 ATOM 713 O O . ASP A 1 108 ? -75.562 -34.251 15.620 1.00 82.35 ? 134 ASP A O 1 ATOM 714 C CB . ASP A 1 108 ? -74.148 -31.997 16.098 1.00 95.32 ? 134 ASP A CB 1 ATOM 715 C CG . ASP A 1 108 ? -73.630 -32.442 17.423 1.00 92.30 ? 134 ASP A CG 1 ATOM 716 O OD1 . ASP A 1 108 ? -72.644 -33.185 17.446 1.00 95.36 ? 134 ASP A OD1 1 ATOM 717 O OD2 . ASP A 1 108 ? -74.206 -32.061 18.445 1.00 111.24 ? 134 ASP A OD2 1 ATOM 718 N N . ASN A 1 109 ? -74.642 -34.662 13.635 1.00 92.62 ? 135 ASN A N 1 ATOM 719 C CA . ASN A 1 109 ? -75.481 -35.797 13.352 1.00 85.97 ? 135 ASN A CA 1 ATOM 720 C C . ASN A 1 109 ? -74.666 -37.066 13.252 1.00 86.54 ? 135 ASN A C 1 ATOM 721 O O . ASN A 1 109 ? -75.137 -38.086 12.827 1.00 86.23 ? 135 ASN A O 1 ATOM 722 C CB . ASN A 1 109 ? -76.313 -35.527 12.115 1.00 83.03 ? 135 ASN A CB 1 ATOM 723 C CG . ASN A 1 109 ? -77.432 -34.562 12.393 1.00 86.49 ? 135 ASN A CG 1 ATOM 724 O OD1 . ASN A 1 109 ? -77.861 -34.422 13.523 1.00 86.40 ? 135 ASN A OD1 1 ATOM 725 N ND2 . ASN A 1 109 ? -77.906 -33.894 11.375 1.00 87.62 ? 135 ASN A ND2 1 ATOM 726 N N . GLN A 1 110 ? -73.410 -36.985 13.624 1.00 83.74 ? 136 GLN A N 1 ATOM 727 C CA . GLN A 1 110 ? -72.615 -38.173 13.796 1.00 94.34 ? 136 GLN A CA 1 ATOM 728 C C . GLN A 1 110 ? -72.411 -38.982 12.542 1.00 93.35 ? 136 GLN A C 1 ATOM 729 O O . GLN A 1 110 ? -72.153 -40.161 12.620 1.00 97.08 ? 136 GLN A O 1 ATOM 730 C CB . GLN A 1 110 ? -73.279 -39.061 14.818 1.00 102.98 ? 136 GLN A CB 1 ATOM 731 C CG . GLN A 1 110 ? -72.297 -39.742 15.738 1.00 111.33 ? 136 GLN A CG 1 ATOM 732 C CD . GLN A 1 110 ? -72.030 -38.927 16.970 1.00 108.60 ? 136 GLN A CD 1 ATOM 733 O OE1 . GLN A 1 110 ? -72.873 -38.151 17.403 1.00 111.24 ? 136 GLN A OE1 1 ATOM 734 N NE2 . GLN A 1 110 ? -70.850 -39.088 17.538 1.00 124.27 ? 136 GLN A NE2 1 ATOM 735 N N . LEU A 1 111 ? -72.479 -38.352 11.388 1.00 95.53 ? 137 LEU A N 1 ATOM 736 C CA . LEU A 1 111 ? -72.345 -39.078 10.149 1.00 82.97 ? 137 LEU A CA 1 ATOM 737 C C . LEU A 1 111 ? -70.984 -39.646 9.892 1.00 92.70 ? 137 LEU A C 1 ATOM 738 O O . LEU A 1 111 ? -69.966 -39.097 10.305 1.00 90.80 ? 137 LEU A O 1 ATOM 739 C CB . LEU A 1 111 ? -72.742 -38.205 8.984 1.00 83.19 ? 137 LEU A CB 1 ATOM 740 C CG . LEU A 1 111 ? -73.991 -37.370 9.151 1.00 89.60 ? 137 LEU A CG 1 ATOM 741 C CD1 . LEU A 1 111 ? -74.646 -37.201 7.807 1.00 90.94 ? 137 LEU A CD1 1 ATOM 742 C CD2 . LEU A 1 111 ? -74.971 -37.974 10.131 1.00 100.11 ? 137 LEU A CD2 1 ATOM 743 N N . PRO A 1 112 ? -71.010 -40.849 9.181 1.00 100.79 ? 138 PRO A N 1 ATOM 744 C CA . PRO A 1 112 ? -69.693 -41.343 8.832 1.00 87.31 ? 138 PRO A CA 1 ATOM 745 C C . PRO A 1 112 ? -69.460 -41.188 7.355 1.00 86.19 ? 138 PRO A C 1 ATOM 746 O O . PRO A 1 112 ? -68.371 -41.486 6.897 1.00 72.51 ? 138 PRO A O 1 ATOM 747 C CB . PRO A 1 112 ? -69.795 -42.812 9.183 1.00 90.14 ? 138 PRO A CB 1 ATOM 748 C CG . PRO A 1 112 ? -71.219 -43.164 8.912 1.00 95.51 ? 138 PRO A CG 1 ATOM 749 C CD . PRO A 1 112 ? -71.968 -41.911 8.626 1.00 98.02 ? 138 PRO A CD 1 ATOM 750 N N . GLN A 1 113 ? -70.446 -40.711 6.610 1.00 77.80 ? 139 GLN A N 1 ATOM 751 C CA . GLN A 1 113 ? -70.175 -40.422 5.191 1.00 97.68 ? 139 GLN A CA 1 ATOM 752 C C . GLN A 1 113 ? -71.001 -39.244 4.666 1.00 94.21 ? 139 GLN A C 1 ATOM 753 O O . GLN A 1 113 ? -71.973 -38.808 5.281 1.00 84.09 ? 139 GLN A O 1 ATOM 754 C CB . GLN A 1 113 ? -70.441 -41.655 4.290 1.00 118.98 ? 139 GLN A CB 1 ATOM 755 C CG . GLN A 1 113 ? -69.557 -42.881 4.528 1.00 124.22 ? 139 GLN A CG 1 ATOM 756 C CD . GLN A 1 113 ? -68.067 -42.615 4.316 1.00 132.31 ? 139 GLN A CD 1 ATOM 757 O OE1 . GLN A 1 113 ? -67.636 -41.467 4.136 1.00 143.28 ? 139 GLN A OE1 1 ATOM 758 N NE2 . GLN A 1 113 ? -67.268 -43.677 4.379 1.00 119.91 ? 139 GLN A NE2 1 ATOM 759 N N . ILE A 1 114 ? -70.604 -38.744 3.506 1.00 92.43 ? 140 ILE A N 1 ATOM 760 C CA . ILE A 1 114 ? -71.300 -37.642 2.881 1.00 92.48 ? 140 ILE A CA 1 ATOM 761 C C . ILE A 1 114 ? -72.536 -38.247 2.228 1.00 92.97 ? 140 ILE A C 1 ATOM 762 O O . ILE A 1 114 ? -72.429 -38.924 1.198 1.00 102.88 ? 140 ILE A O 1 ATOM 763 C CB . ILE A 1 114 ? -70.436 -37.001 1.775 1.00 93.64 ? 140 ILE A CB 1 ATOM 764 C CG1 . ILE A 1 114 ? -69.053 -36.624 2.317 1.00 98.56 ? 140 ILE A CG1 1 ATOM 765 C CG2 . ILE A 1 114 ? -71.166 -35.814 1.171 1.00 88.87 ? 140 ILE A CG2 1 ATOM 766 C CD1 . ILE A 1 114 ? -68.095 -36.114 1.265 1.00 103.01 ? 140 ILE A CD1 1 ATOM 767 N N . PRO A 1 115 ? -73.712 -38.025 2.815 1.00 86.89 ? 141 PRO A N 1 ATOM 768 C CA . PRO A 1 115 ? -74.914 -38.600 2.213 1.00 87.26 ? 141 PRO A CA 1 ATOM 769 C C . PRO A 1 115 ? -74.856 -38.607 0.695 1.00 103.47 ? 141 PRO A C 1 ATOM 770 O O . PRO A 1 115 ? -74.754 -37.541 0.079 1.00 101.14 ? 141 PRO A O 1 ATOM 771 C CB . PRO A 1 115 ? -76.032 -37.678 2.693 1.00 77.19 ? 141 PRO A CB 1 ATOM 772 C CG . PRO A 1 115 ? -75.526 -37.091 3.972 1.00 88.91 ? 141 PRO A CG 1 ATOM 773 C CD . PRO A 1 115 ? -74.017 -37.194 3.989 1.00 92.24 ? 141 PRO A CD 1 ATOM 774 N N . SER A 1 116 ? -74.880 -39.790 0.100 1.00 116.64 ? 142 SER A N 1 ATOM 775 C CA . SER A 1 116 ? -74.813 -39.911 -1.343 1.00 98.06 ? 142 SER A CA 1 ATOM 776 C C . SER A 1 116 ? -76.130 -39.486 -1.922 1.00 84.60 ? 142 SER A C 1 ATOM 777 O O . SER A 1 116 ? -77.114 -39.405 -1.213 1.00 73.93 ? 142 SER A O 1 ATOM 778 C CB . SER A 1 116 ? -74.473 -41.327 -1.750 1.00 89.95 ? 142 SER A CB 1 ATOM 779 O OG . SER A 1 116 ? -73.282 -41.734 -1.127 1.00 92.15 ? 142 SER A OG 1 ATOM 780 N N . GLY A 1 117 ? -76.147 -39.200 -3.211 1.00 77.56 ? 143 GLY A N 1 ATOM 781 C CA . GLY A 1 117 ? -77.369 -38.751 -3.822 1.00 87.18 ? 143 GLY A CA 1 ATOM 782 C C . GLY A 1 117 ? -77.906 -37.494 -3.206 1.00 93.88 ? 143 GLY A C 1 ATOM 783 O O . GLY A 1 117 ? -78.926 -37.481 -2.540 1.00 82.75 ? 143 GLY A O 1 ATOM 784 N N . LEU A 1 118 ? -77.152 -36.427 -3.386 1.00 109.08 ? 144 LEU A N 1 ATOM 785 C CA . LEU A 1 118 ? -77.571 -35.131 -2.916 1.00 99.36 ? 144 LEU A CA 1 ATOM 786 C C . LEU A 1 118 ? -77.968 -34.254 -4.071 1.00 84.96 ? 144 LEU A C 1 ATOM 787 O O . LEU A 1 118 ? -77.449 -34.385 -5.159 1.00 89.15 ? 144 LEU A O 1 ATOM 788 C CB . LEU A 1 118 ? -76.463 -34.488 -2.111 1.00 109.88 ? 144 LEU A CB 1 ATOM 789 C CG . LEU A 1 118 ? -76.600 -34.694 -0.611 1.00 107.95 ? 144 LEU A CG 1 ATOM 790 C CD1 . LEU A 1 118 ? -75.252 -34.557 0.057 1.00 110.76 ? 144 LEU A CD1 1 ATOM 791 C CD2 . LEU A 1 118 ? -77.594 -33.715 -0.030 1.00 92.02 ? 144 LEU A CD2 1 ATOM 792 N N . PRO A 1 119 ? -78.953 -33.306 -3.772 1.00 74.36 ? 145 PRO A N 1 ATOM 793 C CA . PRO A 1 119 ? -79.430 -32.560 -4.944 1.00 76.86 ? 145 PRO A CA 1 ATOM 794 C C . PRO A 1 119 ? -78.385 -31.650 -5.538 1.00 91.15 ? 145 PRO A C 1 ATOM 795 O O . PRO A 1 119 ? -77.396 -31.403 -4.895 1.00 105.12 ? 145 PRO A O 1 ATOM 796 C CB . PRO A 1 119 ? -80.544 -31.687 -4.387 1.00 76.75 ? 145 PRO A CB 1 ATOM 797 C CG . PRO A 1 119 ? -81.028 -32.380 -3.199 1.00 81.64 ? 145 PRO A CG 1 ATOM 798 C CD . PRO A 1 119 ? -79.767 -32.783 -2.569 1.00 78.45 ? 145 PRO A CD 1 ATOM 799 N N . GLU A 1 120 ? -78.566 -31.210 -6.775 1.00 96.80 ? 146 GLU A N 1 ATOM 800 C CA . GLU A 1 120 ? -77.585 -30.350 -7.410 1.00 101.83 ? 146 GLU A CA 1 ATOM 801 C C . GLU A 1 120 ? -77.991 -28.874 -7.237 1.00 101.85 ? 146 GLU A C 1 ATOM 802 O O . GLU A 1 120 ? -77.213 -27.967 -7.516 1.00 104.28 ? 146 GLU A O 1 ATOM 803 C CB . GLU A 1 120 ? -77.381 -30.743 -8.879 1.00 110.58 ? 146 GLU A CB 1 ATOM 804 C CG . GLU A 1 120 ? -76.958 -32.207 -9.042 1.00 119.94 ? 146 GLU A CG 1 ATOM 805 C CD . GLU A 1 120 ? -76.448 -32.564 -10.437 1.00 119.58 ? 146 GLU A CD 1 ATOM 806 O OE1 . GLU A 1 120 ? -76.539 -31.725 -11.361 1.00 111.42 ? 146 GLU A OE1 1 ATOM 807 O OE2 . GLU A 1 120 ? -75.911 -33.685 -10.594 1.00 108.39 ? 146 GLU A OE2 1 ATOM 808 N N . SER A 1 121 ? -79.168 -28.650 -6.664 1.00 89.47 ? 147 SER A N 1 ATOM 809 C CA . SER A 1 121 ? -79.657 -27.307 -6.433 1.00 91.52 ? 147 SER A CA 1 ATOM 810 C C . SER A 1 121 ? -79.019 -26.658 -5.201 1.00 103.26 ? 147 SER A C 1 ATOM 811 O O . SER A 1 121 ? -79.304 -25.497 -4.881 1.00 96.75 ? 147 SER A O 1 ATOM 812 C CB . SER A 1 121 ? -81.162 -27.355 -6.231 1.00 103.16 ? 147 SER A CB 1 ATOM 813 O OG . SER A 1 121 ? -81.496 -28.219 -5.158 1.00 113.13 ? 147 SER A OG 1 ATOM 814 N N . LEU A 1 122 ? -78.179 -27.405 -4.493 1.00 109.04 ? 148 LEU A N 1 ATOM 815 C CA . LEU A 1 122 ? -77.531 -26.876 -3.289 1.00 109.35 ? 148 LEU A CA 1 ATOM 816 C C . LEU A 1 122 ? -76.454 -25.825 -3.505 1.00 94.77 ? 148 LEU A C 1 ATOM 817 O O . LEU A 1 122 ? -75.496 -26.027 -4.258 1.00 86.13 ? 148 LEU A O 1 ATOM 818 C CB . LEU A 1 122 ? -76.916 -27.999 -2.426 1.00 97.53 ? 148 LEU A CB 1 ATOM 819 C CG . LEU A 1 122 ? -77.830 -28.980 -1.681 1.00 89.01 ? 148 LEU A CG 1 ATOM 820 C CD1 . LEU A 1 122 ? -76.969 -29.991 -0.944 1.00 93.15 ? 148 LEU A CD1 1 ATOM 821 C CD2 . LEU A 1 122 ? -78.764 -28.276 -0.700 1.00 78.02 ? 148 LEU A CD2 1 ATOM 822 N N . THR A 1 123 ? -76.626 -24.713 -2.801 1.00 81.76 ? 149 THR A N 1 ATOM 823 C CA . THR A 1 123 ? -75.674 -23.621 -2.815 1.00 82.39 ? 149 THR A CA 1 ATOM 824 C C . THR A 1 123 ? -74.874 -23.671 -1.508 1.00 79.16 ? 149 THR A C 1 ATOM 825 O O . THR A 1 123 ? -73.686 -23.426 -1.510 1.00 87.44 ? 149 THR A O 1 ATOM 826 C CB . THR A 1 123 ? -76.353 -22.253 -2.981 1.00 80.71 ? 149 THR A CB 1 ATOM 827 O OG1 . THR A 1 123 ? -77.310 -22.039 -1.933 1.00 75.95 ? 149 THR A OG1 1 ATOM 828 C CG2 . THR A 1 123 ? -77.044 -22.180 -4.313 1.00 82.15 ? 149 THR A CG2 1 ATOM 829 N N . GLU A 1 124 ? -75.518 -24.078 -0.416 1.00 85.91 ? 150 GLU A N 1 ATOM 830 C CA . GLU A 1 124 ? -74.860 -24.173 0.884 1.00 82.63 ? 150 GLU A CA 1 ATOM 831 C C . GLU A 1 124 ? -75.068 -25.530 1.580 1.00 88.75 ? 150 GLU A C 1 ATOM 832 O O . GLU A 1 124 ? -76.202 -25.914 1.897 1.00 80.25 ? 150 GLU A O 1 ATOM 833 C CB . GLU A 1 124 ? -75.383 -23.092 1.811 1.00 82.34 ? 150 GLU A CB 1 ATOM 834 C CG . GLU A 1 124 ? -74.703 -23.129 3.168 1.00 91.67 ? 150 GLU A CG 1 ATOM 835 C CD . GLU A 1 124 ? -75.234 -22.100 4.135 1.00 101.29 ? 150 GLU A CD 1 ATOM 836 O OE1 . GLU A 1 124 ? -76.158 -21.349 3.762 1.00 118.63 ? 150 GLU A OE1 1 ATOM 837 O OE2 . GLU A 1 124 ? -74.732 -22.059 5.277 1.00 102.24 ? 150 GLU A OE2 1 ATOM 838 N N . LEU A 1 125 ? -73.963 -26.173 1.948 1.00 76.41 ? 151 LEU A N 1 ATOM 839 C CA . LEU A 1 125 ? -74.014 -27.462 2.616 1.00 75.50 ? 151 LEU A CA 1 ATOM 840 C C . LEU A 1 125 ? -73.087 -27.534 3.838 1.00 75.11 ? 151 LEU A C 1 ATOM 841 O O . LEU A 1 125 ? -71.859 -27.487 3.684 1.00 68.12 ? 151 LEU A O 1 ATOM 842 C CB . LEU A 1 125 ? -73.596 -28.574 1.636 1.00 79.13 ? 151 LEU A CB 1 ATOM 843 C CG . LEU A 1 125 ? -73.591 -30.001 2.220 1.00 79.36 ? 151 LEU A CG 1 ATOM 844 C CD1 . LEU A 1 125 ? -74.994 -30.422 2.634 1.00 76.47 ? 151 LEU A CD1 1 ATOM 845 C CD2 . LEU A 1 125 ? -73.002 -30.995 1.240 1.00 77.57 ? 151 LEU A CD2 1 ATOM 846 N N . SER A 1 126 ? -73.657 -27.789 5.022 1.00 69.50 ? 152 SER A N 1 ATOM 847 C CA . SER A 1 126 ? -72.845 -27.898 6.241 1.00 70.31 ? 152 SER A CA 1 ATOM 848 C C . SER A 1 126 ? -72.816 -29.310 6.866 1.00 66.80 ? 152 SER A C 1 ATOM 849 O O . SER A 1 126 ? -73.825 -29.825 7.312 1.00 60.19 ? 152 SER A O 1 ATOM 850 C CB . SER A 1 126 ? -73.323 -26.890 7.295 1.00 70.24 ? 152 SER A CB 1 ATOM 851 O OG . SER A 1 126 ? -72.455 -26.909 8.430 1.00 64.59 ? 152 SER A OG 1 ATOM 852 N N . LEU A 1 127 ? -71.631 -29.886 6.972 1.00 71.95 ? 153 LEU A N 1 ATOM 853 C CA . LEU A 1 127 ? -71.466 -31.209 7.556 1.00 64.41 ? 153 LEU A CA 1 ATOM 854 C C . LEU A 1 127 ? -70.489 -31.100 8.690 1.00 63.51 ? 153 LEU A C 1 ATOM 855 O O . LEU A 1 127 ? -69.594 -31.945 8.858 1.00 76.11 ? 153 LEU A O 1 ATOM 856 C CB . LEU A 1 127 ? -70.910 -32.191 6.512 1.00 79.98 ? 153 LEU A CB 1 ATOM 857 C CG . LEU A 1 127 ? -71.754 -32.410 5.247 1.00 85.63 ? 153 LEU A CG 1 ATOM 858 C CD1 . LEU A 1 127 ? -71.053 -33.389 4.315 1.00 85.49 ? 153 LEU A CD1 1 ATOM 859 C CD2 . LEU A 1 127 ? -73.148 -32.907 5.592 1.00 82.12 ? 153 LEU A CD2 1 ATOM 860 N N . ILE A 1 128 ? -70.644 -30.089 9.513 1.00 70.73 ? 154 ILE A N 1 ATOM 861 C CA . ILE A 1 128 ? -69.769 -29.929 10.662 1.00 80.96 ? 154 ILE A CA 1 ATOM 862 C C . ILE A 1 128 ? -70.037 -30.875 11.820 1.00 79.33 ? 154 ILE A C 1 ATOM 863 O O . ILE A 1 128 ? -71.160 -31.264 12.061 1.00 73.80 ? 154 ILE A O 1 ATOM 864 C CB . ILE A 1 128 ? -69.828 -28.502 11.190 1.00 82.46 ? 154 ILE A CB 1 ATOM 865 C CG1 . ILE A 1 128 ? -69.825 -27.536 10.027 1.00 96.68 ? 154 ILE A CG1 1 ATOM 866 C CG2 . ILE A 1 128 ? -68.647 -28.223 12.080 1.00 73.87 ? 154 ILE A CG2 1 ATOM 867 C CD1 . ILE A 1 128 ? -69.601 -26.101 10.426 1.00 98.09 ? 154 ILE A CD1 1 ATOM 868 N N . GLN A 1 129 ? -69.008 -31.173 12.592 1.00 80.09 ? 155 GLN A N 1 ATOM 869 C CA . GLN A 1 129 ? -69.191 -31.992 13.763 1.00 81.78 ? 155 GLN A CA 1 ATOM 870 C C . GLN A 1 129 ? -69.765 -33.366 13.460 1.00 85.20 ? 155 GLN A C 1 ATOM 871 O O . GLN A 1 129 ? -70.772 -33.772 14.006 1.00 71.89 ? 155 GLN A O 1 ATOM 872 C CB . GLN A 1 129 ? -70.105 -31.256 14.714 1.00 87.18 ? 155 GLN A CB 1 ATOM 873 C CG . GLN A 1 129 ? -69.438 -30.807 15.984 1.00 109.91 ? 155 GLN A CG 1 ATOM 874 C CD . GLN A 1 129 ? -70.359 -29.964 16.823 1.00 120.13 ? 155 GLN A CD 1 ATOM 875 O OE1 . GLN A 1 129 ? -71.082 -29.119 16.310 1.00 108.49 ? 155 GLN A OE1 1 ATOM 876 N NE2 . GLN A 1 129 ? -70.348 -30.199 18.121 1.00 126.70 ? 155 GLN A NE2 1 ATOM 877 N N . ASN A 1 130 ? -69.120 -34.060 12.543 1.00 74.40 ? 156 ASN A N 1 ATOM 878 C CA . ASN A 1 130 ? -69.534 -35.366 12.110 1.00 69.00 ? 156 ASN A CA 1 ATOM 879 C C . ASN A 1 130 ? -68.351 -36.298 12.061 1.00 80.72 ? 156 ASN A C 1 ATOM 880 O O . ASN A 1 130 ? -67.300 -35.965 12.559 1.00 88.95 ? 156 ASN A O 1 ATOM 881 C CB . ASN A 1 130 ? -70.223 -35.270 10.779 1.00 69.30 ? 156 ASN A CB 1 ATOM 882 C CG . ASN A 1 130 ? -71.633 -34.804 10.918 1.00 74.88 ? 156 ASN A CG 1 ATOM 883 O OD1 . ASN A 1 130 ? -72.308 -35.171 11.851 1.00 69.53 ? 156 ASN A OD1 1 ATOM 884 N ND2 . ASN A 1 130 ? -72.083 -33.990 10.001 1.00 78.45 ? 156 ASN A ND2 1 ATOM 885 N N . ASN A 1 131 ? -68.546 -37.501 11.546 1.00 83.30 ? 157 ASN A N 1 ATOM 886 C CA . ASN A 1 131 ? -67.505 -38.518 11.539 1.00 85.20 ? 157 ASN A CA 1 ATOM 887 C C . ASN A 1 131 ? -66.831 -38.827 10.204 1.00 89.06 ? 157 ASN A C 1 ATOM 888 O O . ASN A 1 131 ? -66.189 -39.839 10.058 1.00 110.94 ? 157 ASN A O 1 ATOM 889 C CB . ASN A 1 131 ? -68.034 -39.780 12.176 1.00 87.06 ? 157 ASN A CB 1 ATOM 890 C CG . ASN A 1 131 ? -68.313 -39.598 13.640 1.00 83.51 ? 157 ASN A CG 1 ATOM 891 O OD1 . ASN A 1 131 ? -67.443 -39.193 14.387 1.00 87.99 ? 157 ASN A OD1 1 ATOM 892 N ND2 . ASN A 1 131 ? -69.530 -39.872 14.052 1.00 73.61 ? 157 ASN A ND2 1 ATOM 893 N N . ILE A 1 132 ? -66.984 -37.928 9.250 1.00 91.43 ? 158 ILE A N 1 ATOM 894 C CA . ILE A 1 132 ? -66.684 -38.094 7.836 1.00 72.80 ? 158 ILE A CA 1 ATOM 895 C C . ILE A 1 132 ? -65.195 -38.003 7.694 1.00 74.96 ? 158 ILE A C 1 ATOM 896 O O . ILE A 1 132 ? -64.603 -36.989 8.027 1.00 101.12 ? 158 ILE A O 1 ATOM 897 C CB . ILE A 1 132 ? -67.324 -36.987 7.043 1.00 65.92 ? 158 ILE A CB 1 ATOM 898 C CG1 . ILE A 1 132 ? -68.827 -37.035 7.279 1.00 67.45 ? 158 ILE A CG1 1 ATOM 899 C CG2 . ILE A 1 132 ? -66.969 -37.132 5.582 1.00 71.12 ? 158 ILE A CG2 1 ATOM 900 C CD1 . ILE A 1 132 ? -69.596 -35.902 6.650 1.00 74.89 ? 158 ILE A CD1 1 ATOM 901 N N . TYR A 1 133 ? -64.578 -39.073 7.229 1.00 83.17 ? 159 TYR A N 1 ATOM 902 C CA . TYR A 1 133 ? -63.134 -39.101 7.103 1.00 85.98 ? 159 TYR A CA 1 ATOM 903 C C . TYR A 1 133 ? -62.686 -39.250 5.683 1.00 82.30 ? 159 TYR A C 1 ATOM 904 O O . TYR A 1 133 ? -61.480 -39.287 5.405 1.00 76.68 ? 159 TYR A O 1 ATOM 905 C CB . TYR A 1 133 ? -62.583 -40.240 7.941 1.00 108.96 ? 159 TYR A CB 1 ATOM 906 C CG . TYR A 1 133 ? -63.146 -40.219 9.342 1.00 144.76 ? 159 TYR A CG 1 ATOM 907 C CD1 . TYR A 1 133 ? -62.800 -39.213 10.232 1.00 145.28 ? 159 TYR A CD1 1 ATOM 908 C CD2 . TYR A 1 133 ? -64.002 -41.220 9.786 1.00 162.12 ? 159 TYR A CD2 1 ATOM 909 C CE1 . TYR A 1 133 ? -63.316 -39.180 11.509 1.00 146.09 ? 159 TYR A CE1 1 ATOM 910 C CE2 . TYR A 1 133 ? -64.507 -41.205 11.072 1.00 158.55 ? 159 TYR A CE2 1 ATOM 911 C CZ . TYR A 1 133 ? -64.157 -40.182 11.926 1.00 149.52 ? 159 TYR A CZ 1 ATOM 912 O OH . TYR A 1 133 ? -64.664 -40.147 13.197 1.00 158.48 ? 159 TYR A OH 1 ATOM 913 N N . ASN A 1 134 ? -63.653 -39.295 4.775 1.00 77.58 ? 160 ASN A N 1 ATOM 914 C CA . ASN A 1 134 ? -63.345 -39.437 3.386 1.00 87.51 ? 160 ASN A CA 1 ATOM 915 C C . ASN A 1 134 ? -64.196 -38.442 2.614 1.00 88.45 ? 160 ASN A C 1 ATOM 916 O O . ASN A 1 134 ? -65.438 -38.493 2.682 1.00 80.13 ? 160 ASN A O 1 ATOM 917 C CB . ASN A 1 134 ? -63.634 -40.871 2.932 1.00 95.78 ? 160 ASN A CB 1 ATOM 918 C CG . ASN A 1 134 ? -63.076 -41.174 1.549 1.00 117.30 ? 160 ASN A CG 1 ATOM 919 O OD1 . ASN A 1 134 ? -62.281 -40.395 1.003 1.00 105.65 ? 160 ASN A OD1 1 ATOM 920 N ND2 . ASN A 1 134 ? -63.416 -42.356 1.013 1.00 121.58 ? 160 ASN A ND2 1 ATOM 921 N N . ILE A 1 135 ? -63.527 -37.466 1.992 1.00 80.62 ? 161 ILE A N 1 ATOM 922 C CA . ILE A 1 135 ? -64.206 -36.441 1.184 1.00 86.15 ? 161 ILE A CA 1 ATOM 923 C C . ILE A 1 135 ? -64.075 -36.981 -0.227 1.00 79.15 ? 161 ILE A C 1 ATOM 924 O O . ILE A 1 135 ? -62.953 -37.089 -0.786 1.00 70.16 ? 161 ILE A O 1 ATOM 925 C CB . ILE A 1 135 ? -63.608 -35.026 1.390 1.00 90.84 ? 161 ILE A CB 1 ATOM 926 C CG1 . ILE A 1 135 ? -63.740 -34.615 2.861 1.00 85.64 ? 161 ILE A CG1 1 ATOM 927 C CG2 . ILE A 1 135 ? -64.337 -33.991 0.542 1.00 84.15 ? 161 ILE A CG2 1 ATOM 928 C CD1 . ILE A 1 135 ? -65.174 -34.578 3.359 1.00 77.53 ? 161 ILE A CD1 1 ATOM 929 N N . THR A 1 136 ? -65.231 -37.276 -0.816 1.00 73.32 ? 162 THR A N 1 ATOM 930 C CA . THR A 1 136 ? -65.259 -37.929 -2.113 1.00 87.26 ? 162 THR A CA 1 ATOM 931 C C . THR A 1 136 ? -66.063 -37.333 -3.247 1.00 90.94 ? 162 THR A C 1 ATOM 932 O O . THR A 1 136 ? -67.188 -36.824 -3.069 1.00 77.04 ? 162 THR A O 1 ATOM 933 C CB . THR A 1 136 ? -65.824 -39.361 -1.921 1.00 94.53 ? 162 THR A CB 1 ATOM 934 O OG1 . THR A 1 136 ? -67.202 -39.294 -1.500 1.00 85.01 ? 162 THR A OG1 1 ATOM 935 C CG2 . THR A 1 136 ? -65.007 -40.127 -0.870 1.00 86.30 ? 162 THR A CG2 1 ATOM 936 N N . LYS A 1 137 ? -65.589 -37.692 -4.435 1.00 84.52 ? 163 LYS A N 1 ATOM 937 C CA . LYS A 1 137 ? -66.165 -37.253 -5.684 1.00 82.92 ? 163 LYS A CA 1 ATOM 938 C C . LYS A 1 137 ? -67.587 -37.797 -5.821 1.00 87.91 ? 163 LYS A C 1 ATOM 939 O O . LYS A 1 137 ? -68.463 -37.128 -6.369 1.00 92.48 ? 163 LYS A O 1 ATOM 940 C CB . LYS A 1 137 ? -65.274 -37.715 -6.839 1.00 83.35 ? 163 LYS A CB 1 ATOM 941 C CG . LYS A 1 137 ? -63.786 -37.448 -6.563 1.00 97.65 ? 163 LYS A CG 1 ATOM 942 C CD . LYS A 1 137 ? -62.842 -37.709 -7.732 1.00 99.07 ? 163 LYS A CD 1 ATOM 943 C CE . LYS A 1 137 ? -63.110 -36.740 -8.877 1.00 100.62 ? 163 LYS A CE 1 ATOM 944 N NZ . LYS A 1 137 ? -62.084 -36.863 -9.935 1.00 99.43 ? 163 LYS A NZ 1 ATOM 945 N N . GLU A 1 138 ? -67.844 -38.985 -5.278 1.00 97.55 ? 164 GLU A N 1 ATOM 946 C CA . GLU A 1 138 ? -69.187 -39.547 -5.374 1.00 110.49 ? 164 GLU A CA 1 ATOM 947 C C . GLU A 1 138 ? -70.179 -38.678 -4.637 1.00 99.62 ? 164 GLU A C 1 ATOM 948 O O . GLU A 1 138 ? -71.225 -38.326 -5.167 1.00 105.54 ? 164 GLU A O 1 ATOM 949 C CB . GLU A 1 138 ? -69.274 -40.969 -4.808 1.00 130.28 ? 164 GLU A CB 1 ATOM 950 C CG . GLU A 1 138 ? -70.709 -41.514 -4.859 1.00 147.75 ? 164 GLU A CG 1 ATOM 951 C CD . GLU A 1 138 ? -70.870 -42.903 -4.265 1.00 157.23 ? 164 GLU A CD 1 ATOM 952 O OE1 . GLU A 1 138 ? -69.849 -43.532 -3.920 1.00 165.13 ? 164 GLU A OE1 1 ATOM 953 O OE2 . GLU A 1 138 ? -72.027 -43.370 -4.150 1.00 153.20 ? 164 GLU A OE2 1 ATOM 954 N N . GLY A 1 139 ? -69.839 -38.326 -3.406 1.00 109.83 ? 165 GLY A N 1 ATOM 955 C CA . GLY A 1 139 ? -70.721 -37.517 -2.587 1.00 106.74 ? 165 GLY A CA 1 ATOM 956 C C . GLY A 1 139 ? -70.681 -36.016 -2.799 1.00 95.98 ? 165 GLY A C 1 ATOM 957 O O . GLY A 1 139 ? -71.699 -35.360 -2.604 1.00 88.20 ? 165 GLY A O 1 ATOM 958 N N . ILE A 1 140 ? -69.555 -35.478 -3.261 1.00 90.03 ? 166 ILE A N 1 ATOM 959 C CA . ILE A 1 140 ? -69.395 -34.026 -3.424 1.00 93.51 ? 166 ILE A CA 1 ATOM 960 C C . ILE A 1 140 ? -69.448 -33.420 -4.842 1.00 92.42 ? 166 ILE A C 1 ATOM 961 O O . ILE A 1 140 ? -70.139 -32.446 -5.083 1.00 76.27 ? 166 ILE A O 1 ATOM 962 C CB . ILE A 1 140 ? -68.129 -33.575 -2.659 1.00 89.79 ? 166 ILE A CB 1 ATOM 963 C CG1 . ILE A 1 140 ? -68.422 -33.579 -1.180 1.00 90.91 ? 166 ILE A CG1 1 ATOM 964 C CG2 . ILE A 1 140 ? -67.698 -32.168 -2.980 1.00 94.70 ? 166 ILE A CG2 1 ATOM 965 C CD1 . ILE A 1 140 ? -69.678 -32.827 -0.849 1.00 94.03 ? 166 ILE A CD1 1 ATOM 966 N N . SER A 1 141 ? -68.732 -34.012 -5.775 1.00 87.21 ? 167 SER A N 1 ATOM 967 C CA . SER A 1 141 ? -68.431 -33.373 -7.040 1.00 84.08 ? 167 SER A CA 1 ATOM 968 C C . SER A 1 141 ? -69.621 -33.059 -7.903 1.00 82.14 ? 167 SER A C 1 ATOM 969 O O . SER A 1 141 ? -69.543 -32.228 -8.776 1.00 95.29 ? 167 SER A O 1 ATOM 970 C CB . SER A 1 141 ? -67.440 -34.194 -7.817 1.00 88.60 ? 167 SER A CB 1 ATOM 971 O OG . SER A 1 141 ? -66.376 -34.567 -6.981 1.00 100.98 ? 167 SER A OG 1 ATOM 972 N N . ARG A 1 142 ? -70.706 -33.766 -7.702 1.00 92.00 ? 168 ARG A N 1 ATOM 973 C CA . ARG A 1 142 ? -71.909 -33.489 -8.446 1.00 103.93 ? 168 ARG A CA 1 ATOM 974 C C . ARG A 1 142 ? -72.396 -32.104 -8.107 1.00 103.76 ? 168 ARG A C 1 ATOM 975 O O . ARG A 1 142 ? -73.058 -31.468 -8.897 1.00 93.13 ? 168 ARG A O 1 ATOM 976 C CB . ARG A 1 142 ? -72.993 -34.512 -8.125 1.00 123.05 ? 168 ARG A CB 1 ATOM 977 C CG . ARG A 1 142 ? -73.159 -35.600 -9.172 1.00 136.65 ? 168 ARG A CG 1 ATOM 978 C CD . ARG A 1 142 ? -71.927 -36.489 -9.242 1.00 143.79 ? 168 ARG A CD 1 ATOM 979 N NE . ARG A 1 142 ? -72.233 -37.917 -9.168 1.00 145.44 ? 168 ARG A NE 1 ATOM 980 C CZ . ARG A 1 142 ? -73.154 -38.453 -8.376 1.00 143.45 ? 168 ARG A CZ 1 ATOM 981 N NH1 . ARG A 1 142 ? -73.885 -37.691 -7.576 1.00 145.95 ? 168 ARG A NH1 1 ATOM 982 N NH2 . ARG A 1 142 ? -73.345 -39.761 -8.386 1.00 143.35 ? 168 ARG A NH2 1 ATOM 983 N N . LEU A 1 143 ? -72.088 -31.648 -6.905 1.00 101.64 ? 169 LEU A N 1 ATOM 984 C CA . LEU A 1 143 ? -72.831 -30.574 -6.271 1.00 95.09 ? 169 LEU A CA 1 ATOM 985 C C . LEU A 1 143 ? -72.861 -29.238 -7.003 1.00 95.77 ? 169 LEU A C 1 ATOM 986 O O . LEU A 1 143 ? -73.872 -28.560 -7.010 1.00 80.50 ? 169 LEU A O 1 ATOM 987 C CB . LEU A 1 143 ? -72.355 -30.409 -4.847 1.00 98.54 ? 169 LEU A CB 1 ATOM 988 C CG . LEU A 1 143 ? -73.092 -31.252 -3.815 1.00 99.12 ? 169 LEU A CG 1 ATOM 989 C CD1 . LEU A 1 143 ? -74.536 -31.509 -4.182 1.00 90.00 ? 169 LEU A CD1 1 ATOM 990 C CD2 . LEU A 1 143 ? -72.360 -32.540 -3.550 1.00 97.32 ? 169 LEU A CD2 1 ATOM 991 N N . ILE A 1 144 ? -71.754 -28.831 -7.586 1.00 97.60 ? 170 ILE A N 1 ATOM 992 C CA . ILE A 1 144 ? -71.794 -27.900 -8.697 1.00 99.57 ? 170 ILE A CA 1 ATOM 993 C C . ILE A 1 144 ? -72.204 -26.486 -8.351 1.00 86.96 ? 170 ILE A C 1 ATOM 994 O O . ILE A 1 144 ? -71.512 -25.555 -8.681 1.00 83.43 ? 170 ILE A O 1 ATOM 995 C CB . ILE A 1 144 ? -72.605 -28.462 -9.868 1.00 105.22 ? 170 ILE A CB 1 ATOM 996 C CG1 . ILE A 1 144 ? -71.847 -29.627 -10.462 1.00 105.92 ? 170 ILE A CG1 1 ATOM 997 C CG2 . ILE A 1 144 ? -72.761 -27.443 -10.977 1.00 100.64 ? 170 ILE A CG2 1 ATOM 998 C CD1 . ILE A 1 144 ? -70.442 -29.255 -10.865 1.00 105.48 ? 170 ILE A CD1 1 ATOM 999 N N . ASN A 1 145 ? -73.352 -26.329 -7.726 1.00 88.94 ? 171 ASN A N 1 ATOM 1000 C CA . ASN A 1 145 ? -73.840 -25.003 -7.420 1.00 82.77 ? 171 ASN A CA 1 ATOM 1001 C C . ASN A 1 145 ? -73.434 -24.513 -6.067 1.00 92.84 ? 171 ASN A C 1 ATOM 1002 O O . ASN A 1 145 ? -73.916 -23.506 -5.604 1.00 93.21 ? 171 ASN A O 1 ATOM 1003 C CB . ASN A 1 145 ? -75.331 -24.946 -7.542 1.00 81.05 ? 171 ASN A CB 1 ATOM 1004 C CG . ASN A 1 145 ? -75.765 -25.065 -8.955 1.00 94.03 ? 171 ASN A CG 1 ATOM 1005 O OD1 . ASN A 1 145 ? -75.068 -25.655 -9.756 1.00 99.63 ? 171 ASN A OD1 1 ATOM 1006 N ND2 . ASN A 1 145 ? -76.903 -24.496 -9.280 1.00 101.27 ? 171 ASN A ND2 1 ATOM 1007 N N . LEU A 1 146 ? -72.573 -25.256 -5.411 1.00 87.13 ? 172 LEU A N 1 ATOM 1008 C CA . LEU A 1 146 ? -72.162 -24.890 -4.091 1.00 92.96 ? 172 LEU A CA 1 ATOM 1009 C C . LEU A 1 146 ? -71.334 -23.640 -3.979 1.00 88.15 ? 172 LEU A C 1 ATOM 1010 O O . LEU A 1 146 ? -70.257 -23.542 -4.573 1.00 78.59 ? 172 LEU A O 1 ATOM 1011 C CB . LEU A 1 146 ? -71.368 -26.023 -3.450 1.00 89.74 ? 172 LEU A CB 1 ATOM 1012 C CG . LEU A 1 146 ? -72.135 -27.249 -2.988 1.00 78.53 ? 172 LEU A CG 1 ATOM 1013 C CD1 . LEU A 1 146 ? -71.140 -28.305 -2.544 1.00 76.85 ? 172 LEU A CD1 1 ATOM 1014 C CD2 . LEU A 1 146 ? -73.089 -26.875 -1.860 1.00 81.03 ? 172 LEU A CD2 1 ATOM 1015 N N . LYS A 1 147 ? -71.878 -22.678 -3.235 1.00 78.10 ? 173 LYS A N 1 ATOM 1016 C CA . LYS A 1 147 ? -71.182 -21.450 -2.934 1.00 85.13 ? 173 LYS A CA 1 ATOM 1017 C C . LYS A 1 147 ? -70.405 -21.722 -1.634 1.00 75.76 ? 173 LYS A C 1 ATOM 1018 O O . LYS A 1 147 ? -69.199 -21.504 -1.566 1.00 65.32 ? 173 LYS A O 1 ATOM 1019 C CB . LYS A 1 147 ? -72.124 -20.259 -2.702 1.00 93.36 ? 173 LYS A CB 1 ATOM 1020 C CG . LYS A 1 147 ? -72.793 -19.647 -3.924 1.00 109.56 ? 173 LYS A CG 1 ATOM 1021 C CD . LYS A 1 147 ? -73.463 -18.324 -3.520 1.00 113.85 ? 173 LYS A CD 1 ATOM 1022 C CE . LYS A 1 147 ? -74.051 -17.546 -4.691 1.00 106.60 ? 173 LYS A CE 1 ATOM 1023 N NZ . LYS A 1 147 ? -75.161 -18.259 -5.383 1.00 115.79 ? 173 LYS A NZ 1 ATOM 1024 N N . ASN A 1 148 ? -71.110 -22.246 -0.627 1.00 73.25 ? 174 ASN A N 1 ATOM 1025 C CA . ASN A 1 148 ? -70.520 -22.543 0.693 1.00 82.94 ? 174 ASN A CA 1 ATOM 1026 C C . ASN A 1 148 ? -70.560 -24.008 1.178 1.00 75.02 ? 174 ASN A C 1 ATOM 1027 O O . ASN A 1 148 ? -71.621 -24.582 1.433 1.00 72.90 ? 174 ASN A O 1 ATOM 1028 C CB . ASN A 1 148 ? -71.218 -21.681 1.734 1.00 80.68 ? 174 ASN A CB 1 ATOM 1029 C CG . ASN A 1 148 ? -71.112 -20.214 1.426 1.00 71.43 ? 174 ASN A CG 1 ATOM 1030 O OD1 . ASN A 1 148 ? -70.235 -19.788 0.685 1.00 72.99 ? 174 ASN A OD1 1 ATOM 1031 N ND2 . ASN A 1 148 ? -71.979 -19.433 2.020 1.00 66.82 ? 174 ASN A ND2 1 ATOM 1032 N N . LEU A 1 149 ? -69.387 -24.542 1.446 1.00 63.40 ? 175 LEU A N 1 ATOM 1033 C CA . LEU A 1 149 ? -69.259 -25.887 1.911 1.00 60.59 ? 175 LEU A CA 1 ATOM 1034 C C . LEU A 1 149 ? -68.501 -25.917 3.237 1.00 61.76 ? 175 LEU A C 1 ATOM 1035 O O . LEU A 1 149 ? -67.307 -25.591 3.281 1.00 56.44 ? 175 LEU A O 1 ATOM 1036 C CB . LEU A 1 149 ? -68.493 -26.717 0.877 1.00 70.70 ? 175 LEU A CB 1 ATOM 1037 C CG . LEU A 1 149 ? -68.233 -28.187 1.239 1.00 71.47 ? 175 LEU A CG 1 ATOM 1038 C CD1 . LEU A 1 149 ? -69.560 -28.882 1.501 1.00 66.26 ? 175 LEU A CD1 1 ATOM 1039 C CD2 . LEU A 1 149 ? -67.432 -28.905 0.157 1.00 64.95 ? 175 LEU A CD2 1 ATOM 1040 N N . TYR A 1 150 ? -69.157 -26.432 4.282 1.00 62.76 ? 176 TYR A N 1 ATOM 1041 C CA . TYR A 1 150 ? -68.552 -26.532 5.611 1.00 60.19 ? 176 TYR A CA 1 ATOM 1042 C C . TYR A 1 150 ? -68.258 -27.983 6.058 1.00 67.39 ? 176 TYR A C 1 ATOM 1043 O O . TYR A 1 150 ? -69.173 -28.764 6.333 1.00 64.31 ? 176 TYR A O 1 ATOM 1044 C CB . TYR A 1 150 ? -69.470 -25.879 6.630 1.00 64.53 ? 176 TYR A CB 1 ATOM 1045 C CG . TYR A 1 150 ? -69.746 -24.402 6.414 1.00 68.23 ? 176 TYR A CG 1 ATOM 1046 C CD1 . TYR A 1 150 ? -70.856 -23.978 5.698 1.00 72.85 ? 176 TYR A CD1 1 ATOM 1047 C CD2 . TYR A 1 150 ? -68.927 -23.432 6.971 1.00 62.95 ? 176 TYR A CD2 1 ATOM 1048 C CE1 . TYR A 1 150 ? -71.131 -22.625 5.534 1.00 64.98 ? 176 TYR A CE1 1 ATOM 1049 C CE2 . TYR A 1 150 ? -69.213 -22.092 6.829 1.00 57.59 ? 176 TYR A CE2 1 ATOM 1050 C CZ . TYR A 1 150 ? -70.312 -21.699 6.105 1.00 56.79 ? 176 TYR A CZ 1 ATOM 1051 O OH . TYR A 1 150 ? -70.586 -20.362 5.947 1.00 69.44 ? 176 TYR A OH 1 ATOM 1052 N N . LEU A 1 151 ? -66.988 -28.300 6.257 1.00 65.71 ? 177 LEU A N 1 ATOM 1053 C CA . LEU A 1 151 ? -66.606 -29.648 6.668 1.00 60.71 ? 177 LEU A CA 1 ATOM 1054 C C . LEU A 1 151 ? -65.742 -29.675 7.923 1.00 66.27 ? 177 LEU A C 1 ATOM 1055 O O . LEU A 1 151 ? -64.956 -30.601 8.147 1.00 59.83 ? 177 LEU A O 1 ATOM 1056 C CB . LEU A 1 151 ? -65.844 -30.311 5.525 1.00 59.83 ? 177 LEU A CB 1 ATOM 1057 C CG . LEU A 1 151 ? -66.651 -30.429 4.230 1.00 71.91 ? 177 LEU A CG 1 ATOM 1058 C CD1 . LEU A 1 151 ? -65.781 -31.095 3.179 1.00 71.92 ? 177 LEU A CD1 1 ATOM 1059 C CD2 . LEU A 1 151 ? -67.949 -31.205 4.436 1.00 66.43 ? 177 LEU A CD2 1 ATOM 1060 N N . ALA A 1 152 ? -65.929 -28.704 8.787 1.00 67.16 ? 178 ALA A N 1 ATOM 1061 C CA . ALA A 1 152 ? -65.111 -28.647 9.982 1.00 71.84 ? 178 ALA A CA 1 ATOM 1062 C C . ALA A 1 152 ? -65.476 -29.684 11.057 1.00 69.08 ? 178 ALA A C 1 ATOM 1063 O O . ALA A 1 152 ? -66.630 -30.114 11.171 1.00 64.02 ? 178 ALA A O 1 ATOM 1064 C CB . ALA A 1 152 ? -65.196 -27.246 10.572 1.00 69.44 ? 178 ALA A CB 1 ATOM 1065 N N . TRP A 1 153 ? -64.516 -30.020 11.895 1.00 71.48 ? 179 TRP A N 1 ATOM 1066 C CA . TRP A 1 153 ? -64.759 -30.928 12.978 1.00 79.35 ? 179 TRP A CA 1 ATOM 1067 C C . TRP A 1 153 ? -65.222 -32.312 12.606 1.00 73.81 ? 179 TRP A C 1 ATOM 1068 O O . TRP A 1 153 ? -66.242 -32.806 13.113 1.00 60.68 ? 179 TRP A O 1 ATOM 1069 C CB . TRP A 1 153 ? -65.754 -30.289 13.929 1.00 76.84 ? 179 TRP A CB 1 ATOM 1070 C CG . TRP A 1 153 ? -65.301 -29.030 14.576 1.00 80.66 ? 179 TRP A CG 1 ATOM 1071 C CD1 . TRP A 1 153 ? -65.661 -27.741 14.253 1.00 87.41 ? 179 TRP A CD1 1 ATOM 1072 C CD2 . TRP A 1 153 ? -64.422 -28.898 15.714 1.00 83.15 ? 179 TRP A CD2 1 ATOM 1073 N NE1 . TRP A 1 153 ? -65.070 -26.852 15.081 1.00 72.50 ? 179 TRP A NE1 1 ATOM 1074 C CE2 . TRP A 1 153 ? -64.315 -27.479 15.979 1.00 88.37 ? 179 TRP A CE2 1 ATOM 1075 C CE3 . TRP A 1 153 ? -63.732 -29.780 16.508 1.00 90.19 ? 179 TRP A CE3 1 ATOM 1076 C CZ2 . TRP A 1 153 ? -63.542 -26.986 16.994 1.00 86.11 ? 179 TRP A CZ2 1 ATOM 1077 C CZ3 . TRP A 1 153 ? -62.950 -29.270 17.530 1.00 89.34 ? 179 TRP A CZ3 1 ATOM 1078 C CH2 . TRP A 1 153 ? -62.863 -27.906 17.767 1.00 90.07 ? 179 TRP A CH2 1 ATOM 1079 N N . ASN A 1 154 ? -64.523 -32.957 11.686 1.00 67.63 ? 180 ASN A N 1 ATOM 1080 C CA . ASN A 1 154 ? -64.799 -34.355 11.440 1.00 75.04 ? 180 ASN A CA 1 ATOM 1081 C C . ASN A 1 154 ? -63.757 -35.348 11.917 1.00 79.02 ? 180 ASN A C 1 ATOM 1082 O O . ASN A 1 154 ? -64.059 -36.209 12.701 1.00 93.15 ? 180 ASN A O 1 ATOM 1083 C CB . ASN A 1 154 ? -65.188 -34.569 9.999 1.00 65.57 ? 180 ASN A CB 1 ATOM 1084 C CG . ASN A 1 154 ? -66.557 -34.043 9.721 1.00 74.47 ? 180 ASN A CG 1 ATOM 1085 O OD1 . ASN A 1 154 ? -67.408 -34.723 9.206 1.00 72.23 ? 180 ASN A OD1 1 ATOM 1086 N ND2 . ASN A 1 154 ? -66.785 -32.831 10.111 1.00 97.44 ? 180 ASN A ND2 1 ATOM 1087 N N . CYS A 1 155 ? -62.525 -35.185 11.502 1.00 76.47 ? 181 CYS A N 1 ATOM 1088 C CA . CYS A 1 155 ? -61.440 -36.040 11.906 1.00 83.89 ? 181 CYS A CA 1 ATOM 1089 C C . CYS A 1 155 ? -60.576 -35.289 12.882 1.00 86.66 ? 181 CYS A C 1 ATOM 1090 O O . CYS A 1 155 ? -59.358 -35.218 12.713 1.00 90.98 ? 181 CYS A O 1 ATOM 1091 C CB . CYS A 1 155 ? -60.589 -36.440 10.707 1.00 106.60 ? 181 CYS A CB 1 ATOM 1092 S SG . CYS A 1 155 ? -59.213 -37.551 11.111 1.00 120.81 ? 181 CYS A SG 1 ATOM 1093 N N . TYR A 1 156 ? -61.179 -34.644 13.868 1.00 90.54 ? 182 TYR A N 1 ATOM 1094 C CA . TYR A 1 156 ? -60.337 -33.939 14.803 1.00 103.74 ? 182 TYR A CA 1 ATOM 1095 C C . TYR A 1 156 ? -59.894 -34.941 15.825 1.00 120.46 ? 182 TYR A C 1 ATOM 1096 O O . TYR A 1 156 ? -60.632 -35.272 16.764 1.00 118.01 ? 182 TYR A O 1 ATOM 1097 C CB . TYR A 1 156 ? -60.991 -32.719 15.440 1.00 99.57 ? 182 TYR A CB 1 ATOM 1098 C CG . TYR A 1 156 ? -59.970 -31.903 16.227 1.00 98.79 ? 182 TYR A CG 1 ATOM 1099 C CD1 . TYR A 1 156 ? -58.812 -31.431 15.596 1.00 95.34 ? 182 TYR A CD1 1 ATOM 1100 C CD2 . TYR A 1 156 ? -60.241 -31.447 17.515 1.00 108.62 ? 182 TYR A CD2 1 ATOM 1101 C CE1 . TYR A 1 156 ? -57.887 -30.660 16.271 1.00 96.74 ? 182 TYR A CE1 1 ATOM 1102 C CE2 . TYR A 1 156 ? -59.331 -30.650 18.199 1.00 104.67 ? 182 TYR A CE2 1 ATOM 1103 C CZ . TYR A 1 156 ? -58.157 -30.255 17.570 1.00 109.33 ? 182 TYR A CZ 1 ATOM 1104 O OH . TYR A 1 156 ? -57.253 -29.452 18.230 1.00 102.29 ? 182 TYR A OH 1 ATOM 1105 N N . PHE A 1 157 ? -58.687 -35.451 15.606 1.00 135.81 ? 183 PHE A N 1 ATOM 1106 C CA . PHE A 1 157 ? -58.112 -36.447 16.477 1.00 148.95 ? 183 PHE A CA 1 ATOM 1107 C C . PHE A 1 157 ? -58.535 -36.198 17.941 1.00 143.41 ? 183 PHE A C 1 ATOM 1108 O O . PHE A 1 157 ? -58.363 -35.091 18.487 1.00 109.14 ? 183 PHE A O 1 ATOM 1109 C CB . PHE A 1 157 ? -56.581 -36.487 16.331 1.00 152.26 ? 183 PHE A CB 1 ATOM 1110 C CG . PHE A 1 157 ? -55.887 -35.268 16.857 1.00 155.49 ? 183 PHE A CG 1 ATOM 1111 C CD1 . PHE A 1 157 ? -55.555 -34.220 16.012 1.00 155.25 ? 183 PHE A CD1 1 ATOM 1112 C CD2 . PHE A 1 157 ? -55.579 -35.163 18.208 1.00 143.86 ? 183 PHE A CD2 1 ATOM 1113 C CE1 . PHE A 1 157 ? -54.909 -33.099 16.501 1.00 146.06 ? 183 PHE A CE1 1 ATOM 1114 C CE2 . PHE A 1 157 ? -54.947 -34.041 18.704 1.00 138.48 ? 183 PHE A CE2 1 ATOM 1115 C CZ . PHE A 1 157 ? -54.603 -33.011 17.848 1.00 139.89 ? 183 PHE A CZ 1 ATOM 1116 N N . ASN A 1 158 ? -59.102 -37.229 18.562 1.00 132.43 ? 184 ASN A N 1 ATOM 1117 C CA . ASN A 1 158 ? -59.307 -38.519 17.902 1.00 147.51 ? 184 ASN A CA 1 ATOM 1118 C C . ASN A 1 158 ? -60.791 -38.787 17.801 1.00 127.14 ? 184 ASN A C 1 ATOM 1119 O O . ASN A 1 158 ? -61.597 -37.978 18.265 1.00 106.81 ? 184 ASN A O 1 ATOM 1120 C CB . ASN A 1 158 ? -58.716 -39.662 18.757 1.00 173.68 ? 184 ASN A CB 1 ATOM 1121 C CG . ASN A 1 158 ? -57.250 -39.458 19.132 1.00 186.95 ? 184 ASN A CG 1 ATOM 1122 O OD1 . ASN A 1 158 ? -56.743 -40.121 20.040 1.00 188.03 ? 184 ASN A OD1 1 ATOM 1123 N ND2 . ASN A 1 158 ? -56.581 -38.530 18.476 1.00 190.08 ? 184 ASN A ND2 1 ATOM 1124 N N . LYS A 1 159 ? -61.143 -39.848 17.078 1.00 113.07 ? 185 LYS A N 1 ATOM 1125 C CA . LYS A 1 159 ? -62.540 -40.289 16.980 1.00 142.30 ? 185 LYS A CA 1 ATOM 1126 C C . LYS A 1 159 ? -62.773 -41.822 17.166 1.00 136.41 ? 185 LYS A C 1 ATOM 1127 O O . LYS A 1 159 ? -63.878 -42.205 17.544 1.00 123.38 ? 185 LYS A O 1 ATOM 1128 C CB . LYS A 1 159 ? -63.285 -39.770 15.735 1.00 163.01 ? 185 LYS A CB 1 ATOM 1129 C CG . LYS A 1 159 ? -63.513 -38.254 15.648 1.00 154.54 ? 185 LYS A CG 1 ATOM 1130 C CD . LYS A 1 159 ? -64.143 -37.561 16.876 1.00 148.99 ? 185 LYS A CD 1 ATOM 1131 C CE . LYS A 1 159 ? -65.509 -38.065 17.365 1.00 151.92 ? 185 LYS A CE 1 ATOM 1132 N NZ . LYS A 1 159 ? -65.522 -39.348 18.136 1.00 149.93 ? 185 LYS A NZ 1 ATOM 1133 N N . VAL A 1 160 ? -61.791 -42.704 16.923 1.00 144.25 ? 186 VAL A N 1 ATOM 1134 C CA . VAL A 1 160 ? -60.434 -42.376 16.466 1.00 160.69 ? 186 VAL A CA 1 ATOM 1135 C C . VAL A 1 160 ? -60.436 -42.121 14.966 1.00 162.15 ? 186 VAL A C 1 ATOM 1136 O O . VAL A 1 160 ? -61.306 -42.612 14.235 1.00 132.44 ? 186 VAL A O 1 ATOM 1137 C CB . VAL A 1 160 ? -59.413 -43.520 16.786 1.00 157.54 ? 186 VAL A CB 1 ATOM 1138 C CG1 . VAL A 1 160 ? -58.072 -43.303 16.080 1.00 143.19 ? 186 VAL A CG1 1 ATOM 1139 C CG2 . VAL A 1 160 ? -59.206 -43.666 18.289 1.00 143.26 ? 186 VAL A CG2 1 ATOM 1140 N N . CYS A 1 161 ? -59.473 -41.317 14.528 1.00 162.93 ? 187 CYS A N 1 ATOM 1141 C CA . CYS A 1 161 ? -59.326 -40.982 13.131 1.00 136.71 ? 187 CYS A CA 1 ATOM 1142 C C . CYS A 1 161 ? -57.901 -40.554 12.844 1.00 130.98 ? 187 CYS A C 1 ATOM 1143 O O . CYS A 1 161 ? -57.410 -39.579 13.418 1.00 132.90 ? 187 CYS A O 1 ATOM 1144 C CB . CYS A 1 161 ? -60.270 -39.863 12.748 1.00 131.00 ? 187 CYS A CB 1 ATOM 1145 S SG . CYS A 1 161 ? -60.061 -39.393 11.021 1.00 167.67 ? 187 CYS A SG 1 ATOM 1146 N N . GLU A 1 162 ? -57.243 -41.291 11.954 1.00 126.86 ? 188 GLU A N 1 ATOM 1147 C CA . GLU A 1 162 ? -55.864 -40.995 11.577 1.00 130.34 ? 188 GLU A CA 1 ATOM 1148 C C . GLU A 1 162 ? -55.747 -39.615 10.894 1.00 126.96 ? 188 GLU A C 1 ATOM 1149 O O . GLU A 1 162 ? -55.171 -38.688 11.471 1.00 120.33 ? 188 GLU A O 1 ATOM 1150 C CB . GLU A 1 162 ? -55.262 -42.143 10.727 1.00 142.21 ? 188 GLU A CB 1 ATOM 1151 C CG . GLU A 1 162 ? -56.067 -42.564 9.494 1.00 143.28 ? 188 GLU A CG 1 ATOM 1152 C CD . GLU A 1 162 ? -55.388 -43.654 8.677 1.00 141.84 ? 188 GLU A CD 1 ATOM 1153 O OE1 . GLU A 1 162 ? -55.947 -44.041 7.631 1.00 147.27 ? 188 GLU A OE1 1 ATOM 1154 O OE2 . GLU A 1 162 ? -54.285 -44.103 9.057 1.00 142.13 ? 188 GLU A OE2 1 ATOM 1155 N N . LYS A 1 163 ? -56.292 -39.489 9.682 1.00 115.06 ? 189 LYS A N 1 ATOM 1156 C CA . LYS A 1 163 ? -56.279 -38.235 8.919 1.00 115.77 ? 189 LYS A CA 1 ATOM 1157 C C . LYS A 1 163 ? -57.544 -38.190 8.094 1.00 106.80 ? 189 LYS A C 1 ATOM 1158 O O . LYS A 1 163 ? -58.257 -39.180 8.008 1.00 87.72 ? 189 LYS A O 1 ATOM 1159 C CB . LYS A 1 163 ? -55.096 -38.124 7.925 1.00 123.43 ? 189 LYS A CB 1 ATOM 1160 C CG . LYS A 1 163 ? -53.677 -38.135 8.488 1.00 132.85 ? 189 LYS A CG 1 ATOM 1161 C CD . LYS A 1 163 ? -53.253 -39.498 9.016 1.00 137.12 ? 189 LYS A CD 1 ATOM 1162 C CE . LYS A 1 163 ? -51.814 -39.487 9.510 1.00 142.36 ? 189 LYS A CE 1 ATOM 1163 N NZ . LYS A 1 163 ? -51.387 -40.826 10.007 1.00 148.71 ? 189 LYS A NZ 1 ATOM 1164 N N . THR A 1 164 ? -57.886 -37.011 7.582 1.00 105.61 ? 190 THR A N 1 ATOM 1165 C CA . THR A 1 164 ? -59.044 -36.898 6.717 1.00 98.60 ? 190 THR A CA 1 ATOM 1166 C C . THR A 1 164 ? -58.494 -37.190 5.350 1.00 99.93 ? 190 THR A C 1 ATOM 1167 O O . THR A 1 164 ? -57.319 -36.928 5.086 1.00 94.30 ? 190 THR A O 1 ATOM 1168 C CB . THR A 1 164 ? -59.740 -35.515 6.736 1.00 87.15 ? 190 THR A CB 1 ATOM 1169 O OG1 . THR A 1 164 ? -60.674 -35.459 7.825 1.00 77.33 ? 190 THR A OG1 1 ATOM 1170 C CG2 . THR A 1 164 ? -60.568 -35.330 5.484 1.00 86.64 ? 190 THR A CG2 1 ATOM 1171 N N . ASN A 1 165 ? -59.278 -37.899 4.552 1.00 95.70 ? 191 ASN A N 1 ATOM 1172 C CA . ASN A 1 165 ? -58.868 -38.215 3.213 1.00 86.64 ? 191 ASN A CA 1 ATOM 1173 C C . ASN A 1 165 ? -59.763 -37.475 2.262 1.00 75.54 ? 191 ASN A C 1 ATOM 1174 O O . ASN A 1 165 ? -61.001 -37.556 2.352 1.00 69.85 ? 191 ASN A O 1 ATOM 1175 C CB . ASN A 1 165 ? -58.993 -39.689 2.888 1.00 86.46 ? 191 ASN A CB 1 ATOM 1176 C CG . ASN A 1 165 ? -58.570 -39.981 1.458 1.00 88.69 ? 191 ASN A CG 1 ATOM 1177 O OD1 . ASN A 1 165 ? -57.376 -39.967 1.139 1.00 80.32 ? 191 ASN A OD1 1 ATOM 1178 N ND2 . ASN A 1 165 ? -59.547 -40.283 0.594 1.00 71.98 ? 191 ASN A ND2 1 ATOM 1179 N N . ILE A 1 166 ? -59.122 -36.819 1.308 1.00 74.02 ? 192 ILE A N 1 ATOM 1180 C CA . ILE A 1 166 ? -59.790 -36.038 0.277 1.00 88.57 ? 192 ILE A CA 1 ATOM 1181 C C . ILE A 1 166 ? -59.269 -36.618 -1.014 1.00 87.88 ? 192 ILE A C 1 ATOM 1182 O O . ILE A 1 166 ? -58.076 -36.489 -1.299 1.00 85.69 ? 192 ILE A O 1 ATOM 1183 C CB . ILE A 1 166 ? -59.363 -34.560 0.416 1.00 97.48 ? 192 ILE A CB 1 ATOM 1184 C CG1 . ILE A 1 166 ? -59.890 -34.016 1.752 1.00 97.85 ? 192 ILE A CG1 1 ATOM 1185 C CG2 . ILE A 1 166 ? -59.924 -33.730 -0.731 1.00 103.20 ? 192 ILE A CG2 1 ATOM 1186 C CD1 . ILE A 1 166 ? -59.210 -32.759 2.222 1.00 87.91 ? 192 ILE A CD1 1 ATOM 1187 N N . GLU A 1 167 ? -60.095 -37.295 -1.787 1.00 86.50 ? 193 GLU A N 1 ATOM 1188 C CA . GLU A 1 167 ? -59.559 -37.838 -3.021 1.00 110.95 ? 193 GLU A CA 1 ATOM 1189 C C . GLU A 1 167 ? -59.332 -36.735 -4.026 1.00 100.70 ? 193 GLU A C 1 ATOM 1190 O O . GLU A 1 167 ? -60.118 -35.814 -4.148 1.00 93.96 ? 193 GLU A O 1 ATOM 1191 C CB . GLU A 1 167 ? -60.394 -38.992 -3.584 1.00 124.30 ? 193 GLU A CB 1 ATOM 1192 C CG . GLU A 1 167 ? -59.635 -39.974 -4.489 1.00 126.82 ? 193 GLU A CG 1 ATOM 1193 C CD . GLU A 1 167 ? -58.328 -40.516 -3.914 1.00 118.24 ? 193 GLU A CD 1 ATOM 1194 O OE1 . GLU A 1 167 ? -57.286 -40.400 -4.586 1.00 97.65 ? 193 GLU A OE1 1 ATOM 1195 O OE2 . GLU A 1 167 ? -58.339 -41.093 -2.814 1.00 98.75 ? 193 GLU A OE2 1 ATOM 1196 N N . ASP A 1 168 ? -58.254 -36.870 -4.770 1.00 91.31 ? 194 ASP A N 1 ATOM 1197 C CA . ASP A 1 168 ? -57.699 -35.794 -5.534 1.00 87.93 ? 194 ASP A CA 1 ATOM 1198 C C . ASP A 1 168 ? -58.751 -35.292 -6.488 1.00 86.98 ? 194 ASP A C 1 ATOM 1199 O O . ASP A 1 168 ? -59.391 -36.067 -7.156 1.00 95.25 ? 194 ASP A O 1 ATOM 1200 C CB . ASP A 1 168 ? -56.483 -36.360 -6.255 1.00 84.33 ? 194 ASP A CB 1 ATOM 1201 C CG . ASP A 1 168 ? -55.987 -35.496 -7.361 1.00 97.62 ? 194 ASP A CG 1 ATOM 1202 O OD1 . ASP A 1 168 ? -56.747 -35.237 -8.300 1.00 110.56 ? 194 ASP A OD1 1 ATOM 1203 O OD2 . ASP A 1 168 ? -54.805 -35.122 -7.324 1.00 96.26 ? 194 ASP A OD2 1 ATOM 1204 N N . GLY A 1 169 ? -58.918 -33.978 -6.542 1.00 81.83 ? 195 GLY A N 1 ATOM 1205 C CA . GLY A 1 169 ? -59.876 -33.334 -7.415 1.00 68.54 ? 195 GLY A CA 1 ATOM 1206 C C . GLY A 1 169 ? -61.296 -33.229 -6.920 1.00 73.56 ? 195 GLY A C 1 ATOM 1207 O O . GLY A 1 169 ? -62.158 -32.738 -7.609 1.00 85.71 ? 195 GLY A O 1 ATOM 1208 N N . VAL A 1 170 ? -61.554 -33.674 -5.717 1.00 68.65 ? 196 VAL A N 1 ATOM 1209 C CA . VAL A 1 170 ? -62.916 -33.635 -5.212 1.00 81.46 ? 196 VAL A CA 1 ATOM 1210 C C . VAL A 1 170 ? -63.558 -32.258 -5.419 1.00 87.37 ? 196 VAL A C 1 ATOM 1211 O O . VAL A 1 170 ? -64.754 -32.155 -5.702 1.00 81.83 ? 196 VAL A O 1 ATOM 1212 C CB . VAL A 1 170 ? -62.994 -33.858 -3.683 1.00 87.11 ? 196 VAL A CB 1 ATOM 1213 C CG1 . VAL A 1 170 ? -64.439 -34.159 -3.281 1.00 80.09 ? 196 VAL A CG1 1 ATOM 1214 C CG2 . VAL A 1 170 ? -62.031 -34.923 -3.202 1.00 92.39 ? 196 VAL A CG2 1 ATOM 1215 N N . PHE A 1 171 ? -62.766 -31.200 -5.237 1.00 90.50 ? 197 PHE A N 1 ATOM 1216 C CA . PHE A 1 171 ? -63.290 -29.838 -5.338 1.00 90.80 ? 197 PHE A CA 1 ATOM 1217 C C . PHE A 1 171 ? -63.193 -29.109 -6.671 1.00 98.26 ? 197 PHE A C 1 ATOM 1218 O O . PHE A 1 171 ? -64.094 -28.327 -6.993 1.00 72.49 ? 197 PHE A O 1 ATOM 1219 C CB . PHE A 1 171 ? -62.647 -28.959 -4.276 1.00 85.51 ? 197 PHE A CB 1 ATOM 1220 C CG . PHE A 1 171 ? -62.817 -29.474 -2.884 1.00 73.34 ? 197 PHE A CG 1 ATOM 1221 C CD1 . PHE A 1 171 ? -64.049 -29.413 -2.263 1.00 69.84 ? 197 PHE A CD1 1 ATOM 1222 C CD2 . PHE A 1 171 ? -61.718 -29.892 -2.150 1.00 67.07 ? 197 PHE A CD2 1 ATOM 1223 C CE1 . PHE A 1 171 ? -64.211 -29.870 -0.967 1.00 64.65 ? 197 PHE A CE1 1 ATOM 1224 C CE2 . PHE A 1 171 ? -61.868 -30.340 -0.858 1.00 62.63 ? 197 PHE A CE2 1 ATOM 1225 C CZ . PHE A 1 171 ? -63.121 -30.329 -0.266 1.00 59.25 ? 197 PHE A CZ 1 ATOM 1226 N N . GLU A 1 172 ? -62.136 -29.359 -7.448 1.00 102.65 ? 198 GLU A N 1 ATOM 1227 C CA . GLU A 1 172 ? -61.954 -28.663 -8.738 1.00 101.34 ? 198 GLU A CA 1 ATOM 1228 C C . GLU A 1 172 ? -63.214 -28.553 -9.587 1.00 85.62 ? 198 GLU A C 1 ATOM 1229 O O . GLU A 1 172 ? -63.366 -27.591 -10.337 1.00 88.12 ? 198 GLU A O 1 ATOM 1230 C CB . GLU A 1 172 ? -60.842 -29.282 -9.580 1.00 100.26 ? 198 GLU A CB 1 ATOM 1231 C CG . GLU A 1 172 ? -61.123 -30.696 -10.044 1.00 114.74 ? 198 GLU A CG 1 ATOM 1232 C CD . GLU A 1 172 ? -60.027 -31.236 -10.944 1.00 120.28 ? 198 GLU A CD 1 ATOM 1233 O OE1 . GLU A 1 172 ? -59.054 -30.487 -11.201 1.00 108.98 ? 198 GLU A OE1 1 ATOM 1234 O OE2 . GLU A 1 172 ? -60.145 -32.403 -11.397 1.00 107.38 ? 198 GLU A OE2 1 ATOM 1235 N N . THR A 1 173 ? -64.139 -29.491 -9.440 1.00 76.99 ? 199 THR A N 1 ATOM 1236 C CA . THR A 1 173 ? -65.367 -29.445 -10.246 1.00 91.23 ? 199 THR A CA 1 ATOM 1237 C C . THR A 1 173 ? -66.383 -28.465 -9.680 1.00 79.83 ? 199 THR A C 1 ATOM 1238 O O . THR A 1 173 ? -67.459 -28.298 -10.244 1.00 93.13 ? 199 THR A O 1 ATOM 1239 C CB . THR A 1 173 ? -66.048 -30.845 -10.382 1.00 108.88 ? 199 THR A CB 1 ATOM 1240 O OG1 . THR A 1 173 ? -66.697 -31.233 -9.156 1.00 98.57 ? 199 THR A OG1 1 ATOM 1241 C CG2 . THR A 1 173 ? -65.024 -31.918 -10.824 1.00 100.39 ? 199 THR A CG2 1 ATOM 1242 N N . LEU A 1 174 ? -66.078 -27.907 -8.512 1.00 92.12 ? 200 LEU A N 1 ATOM 1243 C CA . LEU A 1 174 ? -66.951 -26.943 -7.825 1.00 95.09 ? 200 LEU A CA 1 ATOM 1244 C C . LEU A 1 174 ? -66.441 -25.558 -8.169 1.00 98.98 ? 200 LEU A C 1 ATOM 1245 O O . LEU A 1 174 ? -65.745 -24.897 -7.378 1.00 89.44 ? 200 LEU A O 1 ATOM 1246 C CB . LEU A 1 174 ? -66.883 -27.171 -6.322 1.00 100.24 ? 200 LEU A CB 1 ATOM 1247 C CG . LEU A 1 174 ? -67.335 -28.555 -5.877 1.00 99.93 ? 200 LEU A CG 1 ATOM 1248 C CD1 . LEU A 1 174 ? -67.009 -28.754 -4.406 1.00 99.86 ? 200 LEU A CD1 1 ATOM 1249 C CD2 . LEU A 1 174 ? -68.822 -28.751 -6.171 1.00 90.99 ? 200 LEU A CD2 1 ATOM 1250 N N . THR A 1 175 ? -66.859 -25.105 -9.339 1.00 96.23 ? 201 THR A N 1 ATOM 1251 C CA . THR A 1 175 ? -66.426 -23.838 -9.881 1.00 83.16 ? 201 THR A CA 1 ATOM 1252 C C . THR A 1 175 ? -67.140 -22.588 -9.394 1.00 80.54 ? 201 THR A C 1 ATOM 1253 O O . THR A 1 175 ? -66.809 -21.487 -9.842 1.00 77.11 ? 201 THR A O 1 ATOM 1254 C CB . THR A 1 175 ? -66.448 -23.905 -11.404 1.00 82.53 ? 201 THR A CB 1 ATOM 1255 O OG1 . THR A 1 175 ? -67.793 -24.118 -11.860 1.00 74.65 ? 201 THR A OG1 1 ATOM 1256 C CG2 . THR A 1 175 ? -65.531 -25.042 -11.875 1.00 70.16 ? 201 THR A CG2 1 ATOM 1257 N N . ASN A 1 176 ? -68.142 -22.752 -8.536 1.00 68.98 ? 202 ASN A N 1 ATOM 1258 C CA . ASN A 1 176 ? -68.856 -21.606 -7.953 1.00 81.23 ? 202 ASN A CA 1 ATOM 1259 C C . ASN A 1 176 ? -68.615 -21.617 -6.444 1.00 79.57 ? 202 ASN A C 1 ATOM 1260 O O . ASN A 1 176 ? -69.348 -20.985 -5.663 1.00 66.40 ? 202 ASN A O 1 ATOM 1261 C CB . ASN A 1 176 ? -70.350 -21.715 -8.204 1.00 83.26 ? 202 ASN A CB 1 ATOM 1262 C CG . ASN A 1 176 ? -70.688 -21.715 -9.663 1.00 96.43 ? 202 ASN A CG 1 ATOM 1263 O OD1 . ASN A 1 176 ? -69.805 -21.698 -10.521 1.00 102.24 ? 202 ASN A OD1 1 ATOM 1264 N ND2 . ASN A 1 176 ? -71.976 -21.746 -9.962 1.00 104.28 ? 202 ASN A ND2 1 ATOM 1265 N N . LEU A 1 177 ? -67.564 -22.319 -6.043 1.00 70.01 ? 203 LEU A N 1 ATOM 1266 C CA . LEU A 1 177 ? -67.267 -22.471 -4.641 1.00 78.14 ? 203 LEU A CA 1 ATOM 1267 C C . LEU A 1 177 ? -66.607 -21.230 -4.079 1.00 71.78 ? 203 LEU A C 1 ATOM 1268 O O . LEU A 1 177 ? -65.417 -20.957 -4.320 1.00 68.40 ? 203 LEU A O 1 ATOM 1269 C CB . LEU A 1 177 ? -66.384 -23.722 -4.405 1.00 75.39 ? 203 LEU A CB 1 ATOM 1270 C CG . LEU A 1 177 ? -66.225 -24.182 -2.941 1.00 63.56 ? 203 LEU A CG 1 ATOM 1271 C CD1 . LEU A 1 177 ? -67.565 -24.578 -2.353 1.00 55.86 ? 203 LEU A CD1 1 ATOM 1272 C CD2 . LEU A 1 177 ? -65.256 -25.346 -2.801 1.00 64.43 ? 203 LEU A CD2 1 ATOM 1273 N N . GLU A 1 178 ? -67.378 -20.483 -3.307 1.00 61.86 ? 204 GLU A N 1 ATOM 1274 C CA . GLU A 1 178 ? -66.853 -19.282 -2.688 1.00 69.38 ? 204 GLU A CA 1 ATOM 1275 C C . GLU A 1 178 ? -66.205 -19.492 -1.305 1.00 62.34 ? 204 GLU A C 1 ATOM 1276 O O . GLU A 1 178 ? -65.158 -18.928 -1.030 1.00 57.95 ? 204 GLU A O 1 ATOM 1277 C CB . GLU A 1 178 ? -67.914 -18.203 -2.670 1.00 68.54 ? 204 GLU A CB 1 ATOM 1278 C CG . GLU A 1 178 ? -68.197 -17.679 -4.063 1.00 74.28 ? 204 GLU A CG 1 ATOM 1279 C CD . GLU A 1 178 ? -69.300 -16.652 -4.094 1.00 81.77 ? 204 GLU A CD 1 ATOM 1280 O OE1 . GLU A 1 178 ? -70.118 -16.593 -3.144 1.00 74.05 ? 204 GLU A OE1 1 ATOM 1281 O OE2 . GLU A 1 178 ? -69.380 -15.940 -5.111 1.00 107.81 ? 204 GLU A OE2 1 ATOM 1282 N N . LEU A 1 179 ? -66.768 -20.369 -0.485 1.00 66.26 ? 205 LEU A N 1 ATOM 1283 C CA . LEU A 1 179 ? -66.224 -20.624 0.848 1.00 56.50 ? 205 LEU A CA 1 ATOM 1284 C C . LEU A 1 179 ? -66.049 -22.108 1.122 1.00 60.64 ? 205 LEU A C 1 ATOM 1285 O O . LEU A 1 179 ? -67.006 -22.897 1.036 1.00 59.12 ? 205 LEU A O 1 ATOM 1286 C CB . LEU A 1 179 ? -67.174 -20.053 1.904 1.00 54.72 ? 205 LEU A CB 1 ATOM 1287 C CG . LEU A 1 179 ? -66.759 -20.142 3.389 1.00 63.60 ? 205 LEU A CG 1 ATOM 1288 C CD1 . LEU A 1 179 ? -67.760 -19.429 4.286 1.00 61.89 ? 205 LEU A CD1 1 ATOM 1289 C CD2 . LEU A 1 179 ? -66.604 -21.570 3.856 1.00 68.72 ? 205 LEU A CD2 1 ATOM 1290 N N . LEU A 1 180 ? -64.845 -22.467 1.525 1.00 54.13 ? 206 LEU A N 1 ATOM 1291 C CA . LEU A 1 180 ? -64.516 -23.829 1.864 1.00 55.13 ? 206 LEU A CA 1 ATOM 1292 C C . LEU A 1 180 ? -63.916 -23.864 3.252 1.00 57.54 ? 206 LEU A C 1 ATOM 1293 O O . LEU A 1 180 ? -62.857 -23.270 3.481 1.00 49.90 ? 206 LEU A O 1 ATOM 1294 C CB . LEU A 1 180 ? -63.495 -24.441 0.879 1.00 56.21 ? 206 LEU A CB 1 ATOM 1295 C CG . LEU A 1 180 ? -63.059 -25.892 1.229 1.00 66.13 ? 206 LEU A CG 1 ATOM 1296 C CD1 . LEU A 1 180 ? -64.260 -26.840 1.292 1.00 65.29 ? 206 LEU A CD1 1 ATOM 1297 C CD2 . LEU A 1 180 ? -62.009 -26.443 0.270 1.00 59.63 ? 206 LEU A CD2 1 ATOM 1298 N N . SER A 1 181 ? -64.574 -24.578 4.169 1.00 59.23 ? 207 SER A N 1 ATOM 1299 C CA . SER A 1 181 ? -64.068 -24.723 5.533 1.00 56.78 ? 207 SER A CA 1 ATOM 1300 C C . SER A 1 181 ? -63.676 -26.156 5.892 1.00 59.67 ? 207 SER A C 1 ATOM 1301 O O . SER A 1 181 ? -64.535 -27.024 6.028 1.00 56.70 ? 207 SER A O 1 ATOM 1302 C CB . SER A 1 181 ? -65.083 -24.266 6.547 1.00 58.21 ? 207 SER A CB 1 ATOM 1303 O OG . SER A 1 181 ? -64.586 -24.574 7.851 1.00 62.06 ? 207 SER A OG 1 ATOM 1304 N N . LEU A 1 182 ? -62.393 -26.373 6.144 1.00 61.79 ? 208 LEU A N 1 ATOM 1305 C CA . LEU A 1 182 ? -61.886 -27.686 6.523 1.00 58.45 ? 208 LEU A CA 1 ATOM 1306 C C . LEU A 1 182 ? -61.174 -27.664 7.869 1.00 59.21 ? 208 LEU A C 1 ATOM 1307 O O . LEU A 1 182 ? -60.381 -28.542 8.161 1.00 59.85 ? 208 LEU A O 1 ATOM 1308 C CB . LEU A 1 182 ? -60.889 -28.183 5.467 1.00 60.93 ? 208 LEU A CB 1 ATOM 1309 C CG . LEU A 1 182 ? -61.479 -28.441 4.080 1.00 71.11 ? 208 LEU A CG 1 ATOM 1310 C CD1 . LEU A 1 182 ? -60.389 -28.940 3.150 1.00 70.63 ? 208 LEU A CD1 1 ATOM 1311 C CD2 . LEU A 1 182 ? -62.633 -29.443 4.148 1.00 73.17 ? 208 LEU A CD2 1 ATOM 1312 N N . SER A 1 183 ? -61.426 -26.656 8.689 1.00 68.26 ? 209 SER A N 1 ATOM 1313 C CA . SER A 1 183 ? -60.731 -26.571 9.977 1.00 66.64 ? 209 SER A CA 1 ATOM 1314 C C . SER A 1 183 ? -61.064 -27.720 10.923 1.00 67.28 ? 209 SER A C 1 ATOM 1315 O O . SER A 1 183 ? -62.148 -28.308 10.871 1.00 60.20 ? 209 SER A O 1 ATOM 1316 C CB . SER A 1 183 ? -60.999 -25.220 10.648 1.00 64.32 ? 209 SER A CB 1 ATOM 1317 O OG . SER A 1 183 ? -60.407 -24.156 9.910 1.00 66.09 ? 209 SER A OG 1 ATOM 1318 N N . PHE A 1 184 ? -60.105 -28.051 11.771 1.00 67.87 ? 210 PHE A N 1 ATOM 1319 C CA . PHE A 1 184 ? -60.280 -29.117 12.734 1.00 78.72 ? 210 PHE A CA 1 ATOM 1320 C C . PHE A 1 184 ? -60.539 -30.458 12.054 1.00 76.84 ? 210 PHE A C 1 ATOM 1321 O O . PHE A 1 184 ? -61.582 -31.105 12.257 1.00 57.38 ? 210 PHE A O 1 ATOM 1322 C CB . PHE A 1 184 ? -61.390 -28.771 13.727 1.00 77.40 ? 210 PHE A CB 1 ATOM 1323 C CG . PHE A 1 184 ? -61.117 -27.530 14.494 1.00 71.25 ? 210 PHE A CG 1 ATOM 1324 C CD1 . PHE A 1 184 ? -61.708 -26.332 14.131 1.00 71.92 ? 210 PHE A CD1 1 ATOM 1325 C CD2 . PHE A 1 184 ? -60.144 -27.525 15.482 1.00 70.16 ? 210 PHE A CD2 1 ATOM 1326 C CE1 . PHE A 1 184 ? -61.422 -25.164 14.816 1.00 65.46 ? 210 PHE A CE1 1 ATOM 1327 C CE2 . PHE A 1 184 ? -59.835 -26.362 16.163 1.00 67.47 ? 210 PHE A CE2 1 ATOM 1328 C CZ . PHE A 1 184 ? -60.476 -25.177 15.828 1.00 66.57 ? 210 PHE A CZ 1 ATOM 1329 N N . ASN A 1 185 ? -59.587 -30.801 11.199 1.00 66.21 ? 211 ASN A N 1 ATOM 1330 C CA . ASN A 1 185 ? -59.546 -32.032 10.438 1.00 60.73 ? 211 ASN A CA 1 ATOM 1331 C C . ASN A 1 185 ? -58.083 -32.233 10.152 1.00 72.21 ? 211 ASN A C 1 ATOM 1332 O O . ASN A 1 185 ? -57.367 -31.273 9.858 1.00 75.54 ? 211 ASN A O 1 ATOM 1333 C CB . ASN A 1 185 ? -60.310 -31.927 9.130 1.00 55.36 ? 211 ASN A CB 1 ATOM 1334 C CG . ASN A 1 185 ? -61.804 -31.941 9.315 1.00 58.59 ? 211 ASN A CG 1 ATOM 1335 O OD1 . ASN A 1 185 ? -62.334 -32.705 10.109 1.00 87.18 ? 211 ASN A OD1 1 ATOM 1336 N ND2 . ASN A 1 185 ? -62.497 -31.233 8.455 1.00 73.56 ? 211 ASN A ND2 1 ATOM 1337 N N . SER A 1 186 ? -57.595 -33.448 10.315 1.00 79.65 ? 212 SER A N 1 ATOM 1338 C CA . SER A 1 186 ? -56.187 -33.687 10.048 1.00 88.44 ? 212 SER A CA 1 ATOM 1339 C C . SER A 1 186 ? -55.934 -33.907 8.569 1.00 82.81 ? 212 SER A C 1 ATOM 1340 O O . SER A 1 186 ? -56.365 -34.910 7.992 1.00 91.71 ? 212 SER A O 1 ATOM 1341 C CB . SER A 1 186 ? -55.684 -34.829 10.895 1.00 86.08 ? 212 SER A CB 1 ATOM 1342 O OG . SER A 1 186 ? -56.597 -35.896 10.843 1.00 118.59 ? 212 SER A OG 1 ATOM 1343 N N . LEU A 1 187 ? -55.250 -32.941 7.959 1.00 69.54 ? 213 LEU A N 1 ATOM 1344 C CA . LEU A 1 187 ? -54.954 -32.997 6.555 1.00 65.73 ? 213 LEU A CA 1 ATOM 1345 C C . LEU A 1 187 ? -53.485 -33.191 6.274 1.00 59.89 ? 213 LEU A C 1 ATOM 1346 O O . LEU A 1 187 ? -53.125 -33.765 5.255 1.00 76.14 ? 213 LEU A O 1 ATOM 1347 C CB . LEU A 1 187 ? -55.393 -31.687 5.903 1.00 78.25 ? 213 LEU A CB 1 ATOM 1348 C CG . LEU A 1 187 ? -56.835 -31.249 6.143 1.00 73.79 ? 213 LEU A CG 1 ATOM 1349 C CD1 . LEU A 1 187 ? -57.200 -30.066 5.248 1.00 74.20 ? 213 LEU A CD1 1 ATOM 1350 C CD2 . LEU A 1 187 ? -57.761 -32.402 5.845 1.00 75.92 ? 213 LEU A CD2 1 ATOM 1351 N N . SER A 1 188 ? -52.642 -32.617 7.121 1.00 70.14 ? 214 SER A N 1 ATOM 1352 C CA . SER A 1 188 ? -51.177 -32.686 6.968 1.00 79.56 ? 214 SER A CA 1 ATOM 1353 C C . SER A 1 188 ? -50.687 -31.821 5.795 1.00 83.74 ? 214 SER A C 1 ATOM 1354 O O . SER A 1 188 ? -49.617 -31.189 5.868 1.00 83.16 ? 214 SER A O 1 ATOM 1355 C CB . SER A 1 188 ? -50.681 -34.137 6.816 1.00 93.66 ? 214 SER A CB 1 ATOM 1356 O OG . SER A 1 188 ? -50.906 -34.902 8.000 1.00 96.45 ? 214 SER A OG 1 ATOM 1357 N N . HIS A 1 189 ? -51.463 -31.798 4.716 1.00 80.20 ? 215 HIS A N 1 ATOM 1358 C CA . HIS A 1 189 ? -51.115 -31.022 3.542 1.00 78.64 ? 215 HIS A CA 1 ATOM 1359 C C . HIS A 1 189 ? -52.381 -30.412 3.016 1.00 76.86 ? 215 HIS A C 1 ATOM 1360 O O . HIS A 1 189 ? -53.458 -31.010 3.125 1.00 70.13 ? 215 HIS A O 1 ATOM 1361 C CB . HIS A 1 189 ? -50.499 -31.911 2.447 1.00 90.03 ? 215 HIS A CB 1 ATOM 1362 C CG . HIS A 1 189 ? -49.234 -32.605 2.860 1.00 111.20 ? 215 HIS A CG 1 ATOM 1363 N ND1 . HIS A 1 189 ? -47.982 -32.065 2.647 1.00 126.10 ? 215 HIS A ND1 1 ATOM 1364 C CD2 . HIS A 1 189 ? -49.026 -33.807 3.452 1.00 119.31 ? 215 HIS A CD2 1 ATOM 1365 C CE1 . HIS A 1 189 ? -47.059 -32.901 3.092 1.00 123.19 ? 215 HIS A CE1 1 ATOM 1366 N NE2 . HIS A 1 189 ? -47.666 -33.962 3.594 1.00 119.10 ? 215 HIS A NE2 1 ATOM 1367 N N . VAL A 1 190 ? -52.241 -29.226 2.433 1.00 72.18 ? 216 VAL A N 1 ATOM 1368 C CA . VAL A 1 190 ? -53.362 -28.508 1.859 1.00 64.52 ? 216 VAL A CA 1 ATOM 1369 C C . VAL A 1 190 ? -53.791 -29.324 0.656 1.00 61.36 ? 216 VAL A C 1 ATOM 1370 O O . VAL A 1 190 ? -52.958 -29.792 -0.105 1.00 71.50 ? 216 VAL A O 1 ATOM 1371 C CB . VAL A 1 190 ? -52.926 -27.108 1.365 1.00 76.69 ? 216 VAL A CB 1 ATOM 1372 C CG1 . VAL A 1 190 ? -54.083 -26.378 0.699 1.00 76.03 ? 216 VAL A CG1 1 ATOM 1373 C CG2 . VAL A 1 190 ? -52.364 -26.276 2.507 1.00 78.44 ? 216 VAL A CG2 1 ATOM 1374 N N . PRO A 1 191 ? -55.085 -29.489 0.459 1.00 56.82 ? 217 PRO A N 1 ATOM 1375 C CA . PRO A 1 191 ? -55.515 -30.280 -0.697 1.00 57.80 ? 217 PRO A CA 1 ATOM 1376 C C . PRO A 1 191 ? -55.277 -29.573 -2.013 1.00 77.67 ? 217 PRO A C 1 ATOM 1377 O O . PRO A 1 191 ? -55.455 -28.358 -2.091 1.00 81.81 ? 217 PRO A O 1 ATOM 1378 C CB . PRO A 1 191 ? -57.019 -30.444 -0.485 1.00 57.99 ? 217 PRO A CB 1 ATOM 1379 C CG . PRO A 1 191 ? -57.407 -29.429 0.538 1.00 62.11 ? 217 PRO A CG 1 ATOM 1380 C CD . PRO A 1 191 ? -56.188 -29.122 1.348 1.00 57.78 ? 217 PRO A CD 1 ATOM 1381 N N . PRO A 1 192 ? -54.884 -30.328 -3.056 1.00 85.69 ? 218 PRO A N 1 ATOM 1382 C CA . PRO A 1 192 ? -54.672 -29.676 -4.335 1.00 68.64 ? 218 PRO A CA 1 ATOM 1383 C C . PRO A 1 192 ? -55.934 -29.618 -5.151 1.00 73.59 ? 218 PRO A C 1 ATOM 1384 O O . PRO A 1 192 ? -57.023 -29.996 -4.679 1.00 71.74 ? 218 PRO A O 1 ATOM 1385 C CB . PRO A 1 192 ? -53.643 -30.574 -5.038 1.00 73.10 ? 218 PRO A CB 1 ATOM 1386 C CG . PRO A 1 192 ? -53.087 -31.462 -3.978 1.00 76.71 ? 218 PRO A CG 1 ATOM 1387 C CD . PRO A 1 192 ? -54.217 -31.635 -3.007 1.00 77.88 ? 218 PRO A CD 1 ATOM 1388 N N . LYS A 1 193 ? -55.788 -29.106 -6.365 1.00 76.83 ? 219 LYS A N 1 ATOM 1389 C CA . LYS A 1 193 ? -56.894 -28.989 -7.300 1.00 82.71 ? 219 LYS A CA 1 ATOM 1390 C C . LYS A 1 193 ? -58.046 -28.213 -6.662 1.00 68.49 ? 219 LYS A C 1 ATOM 1391 O O . LYS A 1 193 ? -59.203 -28.628 -6.715 1.00 71.55 ? 219 LYS A O 1 ATOM 1392 C CB . LYS A 1 193 ? -57.382 -30.381 -7.751 1.00 97.09 ? 219 LYS A CB 1 ATOM 1393 C CG . LYS A 1 193 ? -56.316 -31.398 -8.207 1.00 104.68 ? 219 LYS A CG 1 ATOM 1394 C CD . LYS A 1 193 ? -55.483 -31.021 -9.428 1.00 121.19 ? 219 LYS A CD 1 ATOM 1395 C CE . LYS A 1 193 ? -54.515 -29.870 -9.178 1.00 138.79 ? 219 LYS A CE 1 ATOM 1396 N NZ . LYS A 1 193 ? -53.681 -29.567 -10.379 1.00 143.00 ? 219 LYS A NZ 1 ATOM 1397 N N . LEU A 1 194 ? -57.725 -27.086 -6.044 1.00 69.03 ? 220 LEU A N 1 ATOM 1398 C CA . LEU A 1 194 ? -58.746 -26.251 -5.425 1.00 68.75 ? 220 LEU A CA 1 ATOM 1399 C C . LEU A 1 194 ? -59.295 -25.352 -6.478 1.00 60.95 ? 220 LEU A C 1 ATOM 1400 O O . LEU A 1 194 ? -58.566 -24.935 -7.360 1.00 61.09 ? 220 LEU A O 1 ATOM 1401 C CB . LEU A 1 194 ? -58.153 -25.420 -4.294 1.00 79.03 ? 220 LEU A CB 1 ATOM 1402 C CG . LEU A 1 194 ? -57.794 -26.216 -3.044 1.00 77.34 ? 220 LEU A CG 1 ATOM 1403 C CD1 . LEU A 1 194 ? -56.839 -25.462 -2.146 1.00 75.49 ? 220 LEU A CD1 1 ATOM 1404 C CD2 . LEU A 1 194 ? -59.079 -26.617 -2.319 1.00 79.43 ? 220 LEU A CD2 1 ATOM 1405 N N . PRO A 1 195 ? -60.591 -25.069 -6.410 1.00 54.87 ? 221 PRO A N 1 ATOM 1406 C CA . PRO A 1 195 ? -61.251 -24.198 -7.380 1.00 55.34 ? 221 PRO A CA 1 ATOM 1407 C C . PRO A 1 195 ? -60.840 -22.707 -7.278 1.00 67.13 ? 221 PRO A C 1 ATOM 1408 O O . PRO A 1 195 ? -60.896 -22.106 -6.204 1.00 75.78 ? 221 PRO A O 1 ATOM 1409 C CB . PRO A 1 195 ? -62.743 -24.381 -7.066 1.00 62.16 ? 221 PRO A CB 1 ATOM 1410 C CG . PRO A 1 195 ? -62.817 -24.913 -5.661 1.00 63.59 ? 221 PRO A CG 1 ATOM 1411 C CD . PRO A 1 195 ? -61.446 -25.405 -5.262 1.00 60.41 ? 221 PRO A CD 1 ATOM 1412 N N . SER A 1 196 ? -60.478 -22.108 -8.404 1.00 69.76 ? 222 SER A N 1 ATOM 1413 C CA . SER A 1 196 ? -60.054 -20.697 -8.434 1.00 68.51 ? 222 SER A CA 1 ATOM 1414 C C . SER A 1 196 ? -61.148 -19.696 -8.027 1.00 62.99 ? 222 SER A C 1 ATOM 1415 O O . SER A 1 196 ? -60.855 -18.519 -7.818 1.00 70.32 ? 222 SER A O 1 ATOM 1416 C CB . SER A 1 196 ? -59.506 -20.321 -9.818 1.00 65.46 ? 222 SER A CB 1 ATOM 1417 O OG . SER A 1 196 ? -60.528 -20.426 -10.808 1.00 73.83 ? 222 SER A OG 1 ATOM 1418 N N . SER A 1 197 ? -62.394 -20.144 -7.910 1.00 61.21 ? 223 SER A N 1 ATOM 1419 C CA . SER A 1 197 ? -63.479 -19.240 -7.503 1.00 57.30 ? 223 SER A CA 1 ATOM 1420 C C . SER A 1 197 ? -63.456 -18.899 -6.007 1.00 63.02 ? 223 SER A C 1 ATOM 1421 O O . SER A 1 197 ? -64.249 -18.058 -5.552 1.00 58.40 ? 223 SER A O 1 ATOM 1422 C CB . SER A 1 197 ? -64.828 -19.886 -7.800 1.00 57.34 ? 223 SER A CB 1 ATOM 1423 O OG . SER A 1 197 ? -64.948 -21.145 -7.157 1.00 64.93 ? 223 SER A OG 1 ATOM 1424 N N . LEU A 1 198 ? -62.654 -19.646 -5.237 1.00 73.54 ? 224 LEU A N 1 ATOM 1425 C CA . LEU A 1 198 ? -62.545 -19.458 -3.774 1.00 73.62 ? 224 LEU A CA 1 ATOM 1426 C C . LEU A 1 198 ? -62.216 -18.073 -3.271 1.00 70.17 ? 224 LEU A C 1 ATOM 1427 O O . LEU A 1 198 ? -61.230 -17.452 -3.683 1.00 66.54 ? 224 LEU A O 1 ATOM 1428 C CB . LEU A 1 198 ? -61.536 -20.443 -3.129 1.00 66.82 ? 224 LEU A CB 1 ATOM 1429 C CG . LEU A 1 198 ? -61.952 -21.903 -2.856 1.00 65.36 ? 224 LEU A CG 1 ATOM 1430 C CD1 . LEU A 1 198 ? -60.796 -22.705 -2.304 1.00 64.00 ? 224 LEU A CD1 1 ATOM 1431 C CD2 . LEU A 1 198 ? -63.099 -21.973 -1.874 1.00 66.78 ? 224 LEU A CD2 1 ATOM 1432 N N . ARG A 1 199 ? -63.040 -17.628 -2.329 1.00 64.55 ? 225 ARG A N 1 ATOM 1433 C CA . ARG A 1 199 ? -62.855 -16.360 -1.681 1.00 66.27 ? 225 ARG A CA 1 ATOM 1434 C C . ARG A 1 199 ? -62.382 -16.560 -0.227 1.00 61.27 ? 225 ARG A C 1 ATOM 1435 O O . ARG A 1 199 ? -61.396 -15.953 0.184 1.00 58.82 ? 225 ARG A O 1 ATOM 1436 C CB . ARG A 1 199 ? -64.057 -15.425 -1.890 1.00 72.75 ? 225 ARG A CB 1 ATOM 1437 C CG . ARG A 1 199 ? -64.147 -15.090 -3.386 1.00 87.91 ? 225 ARG A CG 1 ATOM 1438 C CD . ARG A 1 199 ? -65.023 -13.918 -3.827 1.00 96.46 ? 225 ARG A CD 1 ATOM 1439 N NE . ARG A 1 199 ? -66.456 -14.068 -3.587 1.00 113.06 ? 225 ARG A NE 1 ATOM 1440 C CZ . ARG A 1 199 ? -67.385 -13.250 -4.093 1.00 116.18 ? 225 ARG A CZ 1 ATOM 1441 N NH1 . ARG A 1 199 ? -68.668 -13.437 -3.815 1.00 120.71 ? 225 ARG A NH1 1 ATOM 1442 N NH2 . ARG A 1 199 ? -67.036 -12.250 -4.892 1.00 119.41 ? 225 ARG A NH2 1 ATOM 1443 N N . LYS A 1 200 ? -62.937 -17.546 0.467 1.00 59.61 ? 226 LYS A N 1 ATOM 1444 C CA . LYS A 1 200 ? -62.531 -17.845 1.862 1.00 55.28 ? 226 LYS A CA 1 ATOM 1445 C C . LYS A 1 200 ? -62.103 -19.309 2.053 1.00 51.91 ? 226 LYS A C 1 ATOM 1446 O O . LYS A 1 200 ? -62.859 -20.226 1.779 1.00 50.22 ? 226 LYS A O 1 ATOM 1447 C CB . LYS A 1 200 ? -63.669 -17.523 2.808 1.00 49.06 ? 226 LYS A CB 1 ATOM 1448 C CG . LYS A 1 200 ? -64.003 -16.062 2.797 1.00 56.12 ? 226 LYS A CG 1 ATOM 1449 C CD . LYS A 1 200 ? -65.167 -15.700 3.697 1.00 62.90 ? 226 LYS A CD 1 ATOM 1450 C CE . LYS A 1 200 ? -65.354 -14.193 3.731 1.00 59.24 ? 226 LYS A CE 1 ATOM 1451 N NZ . LYS A 1 200 ? -66.570 -13.842 4.480 1.00 68.38 ? 226 LYS A NZ 1 ATOM 1452 N N . LEU A 1 201 ? -60.883 -19.513 2.513 1.00 46.79 ? 227 LEU A N 1 ATOM 1453 C CA . LEU A 1 201 ? -60.365 -20.843 2.739 1.00 47.00 ? 227 LEU A CA 1 ATOM 1454 C C . LEU A 1 201 ? -59.935 -21.010 4.208 1.00 47.89 ? 227 LEU A C 1 ATOM 1455 O O . LEU A 1 201 ? -58.913 -20.479 4.619 1.00 49.64 ? 227 LEU A O 1 ATOM 1456 C CB . LEU A 1 201 ? -59.179 -21.094 1.825 1.00 46.81 ? 227 LEU A CB 1 ATOM 1457 C CG . LEU A 1 201 ? -58.460 -22.436 1.954 1.00 57.99 ? 227 LEU A CG 1 ATOM 1458 C CD1 . LEU A 1 201 ? -59.393 -23.579 1.648 1.00 59.08 ? 227 LEU A CD1 1 ATOM 1459 C CD2 . LEU A 1 201 ? -57.258 -22.505 1.029 1.00 59.41 ? 227 LEU A CD2 1 ATOM 1460 N N . PHE A 1 202 ? -60.730 -21.734 4.992 1.00 48.52 ? 228 PHE A N 1 ATOM 1461 C CA . PHE A 1 202 ? -60.405 -21.982 6.404 1.00 49.86 ? 228 PHE A CA 1 ATOM 1462 C C . PHE A 1 202 ? -59.666 -23.306 6.616 1.00 51.30 ? 228 PHE A C 1 ATOM 1463 O O . PHE A 1 202 ? -60.184 -24.368 6.302 1.00 51.28 ? 228 PHE A O 1 ATOM 1464 C CB . PHE A 1 202 ? -61.667 -22.013 7.210 1.00 44.68 ? 228 PHE A CB 1 ATOM 1465 C CG . PHE A 1 202 ? -62.422 -20.730 7.197 1.00 45.49 ? 228 PHE A CG 1 ATOM 1466 C CD1 . PHE A 1 202 ? -63.362 -20.479 6.224 1.00 50.43 ? 228 PHE A CD1 1 ATOM 1467 C CD2 . PHE A 1 202 ? -62.226 -19.787 8.188 1.00 47.59 ? 228 PHE A CD2 1 ATOM 1468 C CE1 . PHE A 1 202 ? -64.123 -19.324 6.241 1.00 48.73 ? 228 PHE A CE1 1 ATOM 1469 C CE2 . PHE A 1 202 ? -62.977 -18.615 8.204 1.00 50.32 ? 228 PHE A CE2 1 ATOM 1470 C CZ . PHE A 1 202 ? -63.906 -18.379 7.210 1.00 49.13 ? 228 PHE A CZ 1 ATOM 1471 N N . LEU A 1 203 ? -58.480 -23.253 7.195 1.00 49.45 ? 229 LEU A N 1 ATOM 1472 C CA . LEU A 1 203 ? -57.703 -24.485 7.432 1.00 47.35 ? 229 LEU A CA 1 ATOM 1473 C C . LEU A 1 203 ? -57.059 -24.423 8.790 1.00 48.81 ? 229 LEU A C 1 ATOM 1474 O O . LEU A 1 203 ? -55.860 -24.716 8.931 1.00 48.81 ? 229 LEU A O 1 ATOM 1475 C CB . LEU A 1 203 ? -56.573 -24.604 6.397 1.00 49.55 ? 229 LEU A CB 1 ATOM 1476 C CG . LEU A 1 203 ? -56.958 -24.647 4.912 1.00 57.14 ? 229 LEU A CG 1 ATOM 1477 C CD1 . LEU A 1 203 ? -55.730 -24.478 4.038 1.00 50.25 ? 229 LEU A CD1 1 ATOM 1478 C CD2 . LEU A 1 203 ? -57.730 -25.906 4.542 1.00 54.77 ? 229 LEU A CD2 1 ATOM 1479 N N . SER A 1 204 ? -57.786 -23.925 9.776 1.00 47.41 ? 230 SER A N 1 ATOM 1480 C CA . SER A 1 204 ? -57.210 -23.834 11.131 1.00 58.72 ? 230 SER A CA 1 ATOM 1481 C C . SER A 1 204 ? -57.116 -25.251 11.781 1.00 50.54 ? 230 SER A C 1 ATOM 1482 O O . SER A 1 204 ? -57.971 -26.083 11.536 1.00 50.10 ? 230 SER A O 1 ATOM 1483 C CB . SER A 1 204 ? -58.091 -22.936 12.019 1.00 56.26 ? 230 SER A CB 1 ATOM 1484 O OG . SER A 1 204 ? -57.437 -22.677 13.249 1.00 55.01 ? 230 SER A OG 1 ATOM 1485 N N . ASN A 1 205 ? -56.087 -25.524 12.576 1.00 54.76 ? 231 ASN A N 1 ATOM 1486 C CA . ASN A 1 205 ? -55.988 -26.833 13.239 1.00 58.57 ? 231 ASN A CA 1 ATOM 1487 C C . ASN A 1 205 ? -56.177 -28.004 12.298 1.00 59.47 ? 231 ASN A C 1 ATOM 1488 O O . ASN A 1 205 ? -57.156 -28.775 12.406 1.00 58.44 ? 231 ASN A O 1 ATOM 1489 C CB . ASN A 1 205 ? -57.049 -26.904 14.323 1.00 61.66 ? 231 ASN A CB 1 ATOM 1490 C CG . ASN A 1 205 ? -56.764 -25.972 15.461 1.00 63.48 ? 231 ASN A CG 1 ATOM 1491 O OD1 . ASN A 1 205 ? -57.490 -25.035 15.664 1.00 72.15 ? 231 ASN A OD1 1 ATOM 1492 N ND2 . ASN A 1 205 ? -55.611 -26.126 16.087 1.00 66.13 ? 231 ASN A ND2 1 ATOM 1493 N N . THR A 1 206 ? -55.323 -28.054 11.294 1.00 59.12 ? 232 THR A N 1 ATOM 1494 C CA . THR A 1 206 ? -55.361 -29.113 10.319 1.00 58.24 ? 232 THR A CA 1 ATOM 1495 C C . THR A 1 206 ? -54.009 -29.836 10.323 1.00 60.86 ? 232 THR A C 1 ATOM 1496 O O . THR A 1 206 ? -53.677 -30.590 9.421 1.00 62.76 ? 232 THR A O 1 ATOM 1497 C CB . THR A 1 206 ? -55.667 -28.551 8.926 1.00 57.98 ? 232 THR A CB 1 ATOM 1498 O OG1 . THR A 1 206 ? -54.704 -27.534 8.620 1.00 57.54 ? 232 THR A OG1 1 ATOM 1499 C CG2 . THR A 1 206 ? -57.074 -27.965 8.859 1.00 48.35 ? 232 THR A CG2 1 ATOM 1500 N N . GLN A 1 207 ? -53.224 -29.600 11.353 1.00 65.79 ? 233 GLN A N 1 ATOM 1501 C CA . GLN A 1 207 ? -51.928 -30.245 11.459 1.00 80.39 ? 233 GLN A CA 1 ATOM 1502 C C . GLN A 1 207 ? -51.045 -30.048 10.240 1.00 78.05 ? 233 GLN A C 1 ATOM 1503 O O . GLN A 1 207 ? -50.255 -30.925 9.882 1.00 81.69 ? 233 GLN A O 1 ATOM 1504 C CB . GLN A 1 207 ? -52.102 -31.731 11.735 1.00 88.90 ? 233 GLN A CB 1 ATOM 1505 C CG . GLN A 1 207 ? -52.690 -32.036 13.096 1.00 94.93 ? 233 GLN A CG 1 ATOM 1506 C CD . GLN A 1 207 ? -52.811 -33.520 13.331 1.00 103.10 ? 233 GLN A CD 1 ATOM 1507 O OE1 . GLN A 1 207 ? -52.119 -34.055 14.182 1.00 99.68 ? 233 GLN A OE1 1 ATOM 1508 N NE2 . GLN A 1 207 ? -53.513 -34.212 12.440 1.00 97.01 ? 233 GLN A NE2 1 ATOM 1509 N N . ILE A 1 208 ? -51.144 -28.879 9.630 1.00 79.56 ? 234 ILE A N 1 ATOM 1510 C CA . ILE A 1 208 ? -50.335 -28.576 8.472 1.00 70.85 ? 234 ILE A CA 1 ATOM 1511 C C . ILE A 1 208 ? -49.148 -27.776 8.922 1.00 67.84 ? 234 ILE A C 1 ATOM 1512 O O . ILE A 1 208 ? -49.287 -26.679 9.405 1.00 89.77 ? 234 ILE A O 1 ATOM 1513 C CB . ILE A 1 208 ? -51.118 -27.803 7.439 1.00 69.07 ? 234 ILE A CB 1 ATOM 1514 C CG1 . ILE A 1 208 ? -52.313 -28.636 7.008 1.00 63.27 ? 234 ILE A CG1 1 ATOM 1515 C CG2 . ILE A 1 208 ? -50.224 -27.483 6.257 1.00 74.39 ? 234 ILE A CG2 1 ATOM 1516 C CD1 . ILE A 1 208 ? -53.153 -27.965 5.957 1.00 68.16 ? 234 ILE A CD1 1 ATOM 1517 N N . LYS A 1 209 ? -47.976 -28.343 8.730 1.00 70.13 ? 235 LYS A N 1 ATOM 1518 C CA . LYS A 1 209 ? -46.705 -27.749 9.122 1.00 62.54 ? 235 LYS A CA 1 ATOM 1519 C C . LYS A 1 209 ? -45.975 -27.036 7.999 1.00 62.18 ? 235 LYS A C 1 ATOM 1520 O O . LYS A 1 209 ? -45.170 -26.158 8.250 1.00 67.34 ? 235 LYS A O 1 ATOM 1521 C CB . LYS A 1 209 ? -45.805 -28.884 9.662 1.00 73.08 ? 235 LYS A CB 1 ATOM 1522 C CG . LYS A 1 209 ? -44.292 -28.619 9.712 1.00 88.85 ? 235 LYS A CG 1 ATOM 1523 C CD . LYS A 1 209 ? -43.861 -27.447 10.591 1.00 97.04 ? 235 LYS A CD 1 ATOM 1524 C CE . LYS A 1 209 ? -42.351 -27.271 10.555 1.00 102.98 ? 235 LYS A CE 1 ATOM 1525 N NZ . LYS A 1 209 ? -41.649 -28.489 11.053 1.00 110.91 ? 235 LYS A NZ 1 ATOM 1526 N N . TYR A 1 210 ? -46.193 -27.437 6.758 1.00 68.17 ? 236 TYR A N 1 ATOM 1527 C CA . TYR A 1 210 ? -45.483 -26.792 5.675 1.00 70.57 ? 236 TYR A CA 1 ATOM 1528 C C . TYR A 1 210 ? -46.433 -26.299 4.623 1.00 67.24 ? 236 TYR A C 1 ATOM 1529 O O . TYR A 1 210 ? -47.377 -26.994 4.273 1.00 63.69 ? 236 TYR A O 1 ATOM 1530 C CB . TYR A 1 210 ? -44.425 -27.733 5.075 1.00 75.04 ? 236 TYR A CB 1 ATOM 1531 C CG . TYR A 1 210 ? -43.630 -27.123 3.926 1.00 98.81 ? 236 TYR A CG 1 ATOM 1532 C CD1 . TYR A 1 210 ? -42.580 -26.243 4.175 1.00 113.81 ? 236 TYR A CD1 1 ATOM 1533 C CD2 . TYR A 1 210 ? -43.889 -27.475 2.592 1.00 102.93 ? 236 TYR A CD2 1 ATOM 1534 C CE1 . TYR A 1 210 ? -41.857 -25.673 3.135 1.00 118.75 ? 236 TYR A CE1 1 ATOM 1535 C CE2 . TYR A 1 210 ? -43.154 -26.929 1.543 1.00 96.41 ? 236 TYR A CE2 1 ATOM 1536 C CZ . TYR A 1 210 ? -42.141 -26.027 1.821 1.00 116.39 ? 236 TYR A CZ 1 ATOM 1537 O OH . TYR A 1 210 ? -41.401 -25.465 0.801 1.00 112.39 ? 236 TYR A OH 1 ATOM 1538 N N . ILE A 1 211 ? -46.255 -25.032 4.237 1.00 72.44 ? 237 ILE A N 1 ATOM 1539 C CA . ILE A 1 211 ? -47.063 -24.384 3.195 1.00 70.22 ? 237 ILE A CA 1 ATOM 1540 C C . ILE A 1 211 ? -46.092 -24.124 2.057 1.00 71.57 ? 237 ILE A C 1 ATOM 1541 O O . ILE A 1 211 ? -45.102 -23.410 2.221 1.00 69.26 ? 237 ILE A O 1 ATOM 1542 C CB . ILE A 1 211 ? -47.656 -23.040 3.661 1.00 71.85 ? 237 ILE A CB 1 ATOM 1543 C CG1 . ILE A 1 211 ? -48.604 -23.230 4.853 1.00 63.51 ? 237 ILE A CG1 1 ATOM 1544 C CG2 . ILE A 1 211 ? -48.413 -22.375 2.527 1.00 72.02 ? 237 ILE A CG2 1 ATOM 1545 C CD1 . ILE A 1 211 ? -49.815 -24.075 4.555 1.00 58.52 ? 237 ILE A CD1 1 ATOM 1546 N N . SER A 1 212 ? -46.346 -24.746 0.923 1.00 78.49 ? 238 SER A N 1 ATOM 1547 C CA . SER A 1 212 ? -45.470 -24.606 -0.241 1.00 86.71 ? 238 SER A CA 1 ATOM 1548 C C . SER A 1 212 ? -45.969 -23.587 -1.246 1.00 81.80 ? 238 SER A C 1 ATOM 1549 O O . SER A 1 212 ? -47.170 -23.282 -1.310 1.00 72.75 ? 238 SER A O 1 ATOM 1550 C CB . SER A 1 212 ? -45.371 -25.953 -0.958 1.00 90.33 ? 238 SER A CB 1 ATOM 1551 O OG . SER A 1 212 ? -46.651 -26.343 -1.452 1.00 90.37 ? 238 SER A OG 1 ATOM 1552 N N . GLU A 1 213 ? -45.043 -23.139 -2.091 1.00 85.80 ? 239 GLU A N 1 ATOM 1553 C CA . GLU A 1 213 ? -45.326 -22.173 -3.157 1.00 80.93 ? 239 GLU A CA 1 ATOM 1554 C C . GLU A 1 213 ? -46.536 -22.547 -4.012 1.00 76.34 ? 239 GLU A C 1 ATOM 1555 O O . GLU A 1 213 ? -47.306 -21.681 -4.423 1.00 78.55 ? 239 GLU A O 1 ATOM 1556 C CB . GLU A 1 213 ? -44.108 -22.078 -4.072 1.00 93.58 ? 239 GLU A CB 1 ATOM 1557 C CG . GLU A 1 213 ? -44.352 -21.287 -5.350 1.00 114.51 ? 239 GLU A CG 1 ATOM 1558 C CD . GLU A 1 213 ? -43.126 -21.203 -6.246 1.00 122.48 ? 239 GLU A CD 1 ATOM 1559 O OE1 . GLU A 1 213 ? -42.038 -21.648 -5.813 1.00 124.60 ? 239 GLU A OE1 1 ATOM 1560 O OE2 . GLU A 1 213 ? -43.248 -20.672 -7.377 1.00 115.09 ? 239 GLU A OE2 1 ATOM 1561 N N . GLU A 1 214 ? -46.715 -23.845 -4.234 1.00 73.14 ? 240 GLU A N 1 ATOM 1562 C CA . GLU A 1 214 ? -47.803 -24.371 -5.066 1.00 75.72 ? 240 GLU A CA 1 ATOM 1563 C C . GLU A 1 214 ? -49.117 -24.589 -4.328 1.00 68.47 ? 240 GLU A C 1 ATOM 1564 O O . GLU A 1 214 ? -50.145 -24.895 -4.942 1.00 66.01 ? 240 GLU A O 1 ATOM 1565 C CB . GLU A 1 214 ? -47.378 -25.736 -5.651 1.00 94.12 ? 240 GLU A CB 1 ATOM 1566 C CG . GLU A 1 214 ? -46.089 -25.770 -6.477 1.00 108.31 ? 240 GLU A CG 1 ATOM 1567 C CD . GLU A 1 214 ? -46.167 -24.976 -7.775 1.00 122.61 ? 240 GLU A CD 1 ATOM 1568 O OE1 . GLU A 1 214 ? -46.850 -23.932 -7.816 1.00 120.30 ? 240 GLU A OE1 1 ATOM 1569 O OE2 . GLU A 1 214 ? -45.479 -25.367 -8.744 1.00 137.80 ? 240 GLU A OE2 1 ATOM 1570 N N . ASP A 1 215 ? -49.097 -24.497 -3.011 1.00 70.30 ? 241 ASP A N 1 ATOM 1571 C CA . ASP A 1 215 ? -50.322 -24.734 -2.253 1.00 69.70 ? 241 ASP A CA 1 ATOM 1572 C C . ASP A 1 215 ? -51.524 -23.888 -2.609 1.00 63.45 ? 241 ASP A C 1 ATOM 1573 O O . ASP A 1 215 ? -52.649 -24.386 -2.582 1.00 61.26 ? 241 ASP A O 1 ATOM 1574 C CB . ASP A 1 215 ? -50.035 -24.643 -0.761 1.00 82.23 ? 241 ASP A CB 1 ATOM 1575 C CG . ASP A 1 215 ? -49.308 -25.844 -0.254 1.00 80.66 ? 241 ASP A CG 1 ATOM 1576 O OD1 . ASP A 1 215 ? -49.800 -26.938 -0.578 1.00 80.88 ? 241 ASP A OD1 1 ATOM 1577 O OD2 . ASP A 1 215 ? -48.345 -25.708 0.551 1.00 78.33 ? 241 ASP A OD2 1 ATOM 1578 N N . PHE A 1 216 ? -51.301 -22.611 -2.915 1.00 74.03 ? 242 PHE A N 1 ATOM 1579 C CA . PHE A 1 216 ? -52.405 -21.686 -3.248 1.00 82.23 ? 242 PHE A CA 1 ATOM 1580 C C . PHE A 1 216 ? -52.148 -21.032 -4.594 1.00 90.44 ? 242 PHE A C 1 ATOM 1581 O O . PHE A 1 216 ? -52.672 -19.954 -4.884 1.00 90.25 ? 242 PHE A O 1 ATOM 1582 C CB . PHE A 1 216 ? -52.433 -20.565 -2.214 1.00 77.10 ? 242 PHE A CB 1 ATOM 1583 C CG . PHE A 1 216 ? -52.346 -21.043 -0.805 1.00 69.10 ? 242 PHE A CG 1 ATOM 1584 C CD1 . PHE A 1 216 ? -53.392 -21.727 -0.237 1.00 67.94 ? 242 PHE A CD1 1 ATOM 1585 C CD2 . PHE A 1 216 ? -51.260 -20.710 -0.018 1.00 65.96 ? 242 PHE A CD2 1 ATOM 1586 C CE1 . PHE A 1 216 ? -53.321 -22.163 1.070 1.00 62.94 ? 242 PHE A CE1 1 ATOM 1587 C CE2 . PHE A 1 216 ? -51.202 -21.106 1.293 1.00 67.53 ? 242 PHE A CE2 1 ATOM 1588 C CZ . PHE A 1 216 ? -52.231 -21.840 1.836 1.00 66.52 ? 242 PHE A CZ 1 ATOM 1589 N N . LYS A 1 217 ? -51.497 -21.780 -5.466 1.00 100.68 ? 243 LYS A N 1 ATOM 1590 C CA . LYS A 1 217 ? -51.065 -21.283 -6.762 1.00 108.86 ? 243 LYS A CA 1 ATOM 1591 C C . LYS A 1 217 ? -52.058 -20.417 -7.558 1.00 104.72 ? 243 LYS A C 1 ATOM 1592 O O . LYS A 1 217 ? -51.719 -19.283 -7.971 1.00 79.74 ? 243 LYS A O 1 ATOM 1593 C CB . LYS A 1 217 ? -50.685 -22.461 -7.664 1.00 120.48 ? 243 LYS A CB 1 ATOM 1594 C CG . LYS A 1 217 ? -49.512 -22.163 -8.599 1.00 120.85 ? 243 LYS A CG 1 ATOM 1595 C CD . LYS A 1 217 ? -49.631 -22.925 -9.903 1.00 115.68 ? 243 LYS A CD 1 ATOM 1596 C CE . LYS A 1 217 ? -50.083 -24.365 -9.725 1.00 116.45 ? 243 LYS A CE 1 ATOM 1597 N NZ . LYS A 1 217 ? -50.397 -24.952 -11.057 1.00 112.72 ? 243 LYS A NZ 1 ATOM 1598 N N . GLY A 1 218 ? -53.239 -20.981 -7.840 1.00 83.46 ? 244 GLY A N 1 ATOM 1599 C CA . GLY A 1 218 ? -54.250 -20.287 -8.645 1.00 73.55 ? 244 GLY A CA 1 ATOM 1600 C C . GLY A 1 218 ? -55.435 -19.668 -7.947 1.00 70.92 ? 244 GLY A C 1 ATOM 1601 O O . GLY A 1 218 ? -56.448 -19.385 -8.586 1.00 69.06 ? 244 GLY A O 1 ATOM 1602 N N . LEU A 1 219 ? -55.319 -19.454 -6.642 1.00 84.90 ? 245 LEU A N 1 ATOM 1603 C CA . LEU A 1 219 ? -56.407 -18.879 -5.863 1.00 81.83 ? 245 LEU A CA 1 ATOM 1604 C C . LEU A 1 219 ? -56.234 -17.383 -5.897 1.00 81.75 ? 245 LEU A C 1 ATOM 1605 O O . LEU A 1 219 ? -55.854 -16.760 -4.912 1.00 91.71 ? 245 LEU A O 1 ATOM 1606 C CB . LEU A 1 219 ? -56.323 -19.390 -4.439 1.00 89.88 ? 245 LEU A CB 1 ATOM 1607 C CG . LEU A 1 219 ? -56.346 -20.912 -4.299 1.00 74.25 ? 245 LEU A CG 1 ATOM 1608 C CD1 . LEU A 1 219 ? -56.120 -21.277 -2.849 1.00 71.37 ? 245 LEU A CD1 1 ATOM 1609 C CD2 . LEU A 1 219 ? -57.661 -21.472 -4.808 1.00 69.50 ? 245 LEU A CD2 1 ATOM 1610 N N . ILE A 1 220 ? -56.513 -16.823 -7.062 1.00 77.20 ? 246 ILE A N 1 ATOM 1611 C CA . ILE A 1 220 ? -56.358 -15.403 -7.311 1.00 69.14 ? 246 ILE A CA 1 ATOM 1612 C C . ILE A 1 220 ? -57.486 -14.572 -6.739 1.00 57.92 ? 246 ILE A C 1 ATOM 1613 O O . ILE A 1 220 ? -57.391 -13.373 -6.715 1.00 60.40 ? 246 ILE A O 1 ATOM 1614 C CB . ILE A 1 220 ? -56.226 -15.121 -8.837 1.00 68.82 ? 246 ILE A CB 1 ATOM 1615 C CG1 . ILE A 1 220 ? -57.476 -15.578 -9.588 1.00 69.39 ? 246 ILE A CG1 1 ATOM 1616 C CG2 . ILE A 1 220 ? -55.012 -15.836 -9.392 1.00 67.13 ? 246 ILE A CG2 1 ATOM 1617 C CD1 . ILE A 1 220 ? -57.479 -15.235 -11.059 1.00 74.01 ? 246 ILE A CD1 1 ATOM 1618 N N . ASN A 1 221 ? -58.574 -15.212 -6.344 1.00 57.01 ? 247 ASN A N 1 ATOM 1619 C CA . ASN A 1 221 ? -59.713 -14.511 -5.763 1.00 54.80 ? 247 ASN A CA 1 ATOM 1620 C C . ASN A 1 221 ? -59.806 -14.562 -4.233 1.00 54.14 ? 247 ASN A C 1 ATOM 1621 O O . ASN A 1 221 ? -60.748 -14.015 -3.659 1.00 57.47 ? 247 ASN A O 1 ATOM 1622 C CB . ASN A 1 221 ? -61.009 -15.050 -6.363 1.00 60.82 ? 247 ASN A CB 1 ATOM 1623 C CG . ASN A 1 221 ? -61.181 -14.665 -7.824 1.00 70.57 ? 247 ASN A CG 1 ATOM 1624 O OD1 . ASN A 1 221 ? -61.175 -13.494 -8.148 1.00 75.07 ? 247 ASN A OD1 1 ATOM 1625 N ND2 . ASN A 1 221 ? -61.526 -15.631 -8.663 1.00 77.21 ? 247 ASN A ND2 1 ATOM 1626 N N . LEU A 1 222 ? -58.874 -15.231 -3.564 1.00 57.41 ? 248 LEU A N 1 ATOM 1627 C CA . LEU A 1 222 ? -58.958 -15.300 -2.109 1.00 61.41 ? 248 LEU A CA 1 ATOM 1628 C C . LEU A 1 222 ? -58.928 -13.977 -1.431 1.00 56.12 ? 248 LEU A C 1 ATOM 1629 O O . LEU A 1 222 ? -58.021 -13.193 -1.635 1.00 57.75 ? 248 LEU A O 1 ATOM 1630 C CB . LEU A 1 222 ? -57.822 -16.095 -1.439 1.00 61.69 ? 248 LEU A CB 1 ATOM 1631 C CG . LEU A 1 222 ? -57.808 -17.596 -1.230 1.00 60.07 ? 248 LEU A CG 1 ATOM 1632 C CD1 . LEU A 1 222 ? -56.635 -17.915 -0.314 1.00 57.98 ? 248 LEU A CD1 1 ATOM 1633 C CD2 . LEU A 1 222 ? -59.081 -18.027 -0.538 1.00 63.27 ? 248 LEU A CD2 1 ATOM 1634 N N . THR A 1 223 ? -59.813 -13.843 -0.466 1.00 51.45 ? 249 THR A N 1 ATOM 1635 C CA . THR A 1 223 ? -59.893 -12.670 0.351 1.00 48.80 ? 249 THR A CA 1 ATOM 1636 C C . THR A 1 223 ? -59.569 -13.047 1.790 1.00 50.57 ? 249 THR A C 1 ATOM 1637 O O . THR A 1 223 ? -59.182 -12.200 2.569 1.00 63.05 ? 249 THR A O 1 ATOM 1638 C CB . THR A 1 223 ? -61.277 -12.111 0.305 1.00 51.31 ? 249 THR A CB 1 ATOM 1639 O OG1 . THR A 1 223 ? -62.192 -13.144 0.646 1.00 58.78 ? 249 THR A OG1 1 ATOM 1640 C CG2 . THR A 1 223 ? -61.582 -11.659 -1.088 1.00 64.68 ? 249 THR A CG2 1 ATOM 1641 N N . LEU A 1 224 ? -59.692 -14.335 2.125 1.00 57.94 ? 250 LEU A N 1 ATOM 1642 C CA . LEU A 1 224 ? -59.434 -14.820 3.482 1.00 53.67 ? 250 LEU A CA 1 ATOM 1643 C C . LEU A 1 224 ? -58.751 -16.150 3.538 1.00 52.74 ? 250 LEU A C 1 ATOM 1644 O O . LEU A 1 224 ? -59.185 -17.104 2.904 1.00 57.56 ? 250 LEU A O 1 ATOM 1645 C CB . LEU A 1 224 ? -60.742 -14.916 4.256 1.00 53.01 ? 250 LEU A CB 1 ATOM 1646 C CG . LEU A 1 224 ? -60.635 -15.379 5.710 1.00 55.30 ? 250 LEU A CG 1 ATOM 1647 C CD1 . LEU A 1 224 ? -61.876 -14.997 6.504 1.00 56.65 ? 250 LEU A CD1 1 ATOM 1648 C CD2 . LEU A 1 224 ? -60.322 -16.870 5.846 1.00 62.95 ? 250 LEU A CD2 1 ATOM 1649 N N . LEU A 1 225 ? -57.695 -16.219 4.339 1.00 47.40 ? 251 LEU A N 1 ATOM 1650 C CA . LEU A 1 225 ? -56.949 -17.444 4.509 1.00 47.36 ? 251 LEU A CA 1 ATOM 1651 C C . LEU A 1 225 ? -56.688 -17.670 5.995 1.00 53.28 ? 251 LEU A C 1 ATOM 1652 O O . LEU A 1 225 ? -55.964 -16.895 6.621 1.00 57.50 ? 251 LEU A O 1 ATOM 1653 C CB . LEU A 1 225 ? -55.621 -17.384 3.779 1.00 43.28 ? 251 LEU A CB 1 ATOM 1654 C CG . LEU A 1 225 ? -54.827 -18.675 3.953 1.00 50.06 ? 251 LEU A CG 1 ATOM 1655 C CD1 . LEU A 1 225 ? -55.609 -19.847 3.388 1.00 57.48 ? 251 LEU A CD1 1 ATOM 1656 C CD2 . LEU A 1 225 ? -53.462 -18.615 3.310 1.00 52.76 ? 251 LEU A CD2 1 ATOM 1657 N N . ASP A 1 226 ? -57.227 -18.760 6.532 1.00 51.04 ? 252 ASP A N 1 ATOM 1658 C CA . ASP A 1 226 ? -57.066 -19.114 7.973 1.00 48.79 ? 252 ASP A CA 1 ATOM 1659 C C . ASP A 1 226 ? -56.186 -20.345 8.147 1.00 52.64 ? 252 ASP A C 1 ATOM 1660 O O . ASP A 1 226 ? -56.591 -21.458 7.810 1.00 49.14 ? 252 ASP A O 1 ATOM 1661 C CB . ASP A 1 226 ? -58.439 -19.418 8.596 1.00 47.71 ? 252 ASP A CB 1 ATOM 1662 C CG . ASP A 1 226 ? -58.358 -19.667 10.081 1.00 50.65 ? 252 ASP A CG 1 ATOM 1663 O OD1 . ASP A 1 226 ? -57.226 -19.606 10.598 1.00 51.15 ? 252 ASP A OD1 1 ATOM 1664 O OD2 . ASP A 1 226 ? -59.422 -19.897 10.737 1.00 49.29 ? 252 ASP A OD2 1 ATOM 1665 N N . LEU A 1 227 ? -54.994 -20.130 8.670 1.00 47.32 ? 253 LEU A N 1 ATOM 1666 C CA . LEU A 1 227 ? -54.039 -21.175 8.914 1.00 43.32 ? 253 LEU A CA 1 ATOM 1667 C C . LEU A 1 227 ? -53.677 -21.207 10.390 1.00 48.66 ? 253 LEU A C 1 ATOM 1668 O O . LEU A 1 227 ? -52.554 -21.529 10.769 1.00 46.72 ? 253 LEU A O 1 ATOM 1669 C CB . LEU A 1 227 ? -52.769 -20.864 8.148 1.00 57.11 ? 253 LEU A CB 1 ATOM 1670 C CG . LEU A 1 227 ? -52.883 -20.920 6.633 1.00 67.73 ? 253 LEU A CG 1 ATOM 1671 C CD1 . LEU A 1 227 ? -51.600 -20.404 5.997 1.00 61.13 ? 253 LEU A CD1 1 ATOM 1672 C CD2 . LEU A 1 227 ? -53.176 -22.355 6.211 1.00 70.81 ? 253 LEU A CD2 1 ATOM 1673 N N . SER A 1 228 ? -54.609 -20.849 11.244 1.00 50.18 ? 254 SER A N 1 ATOM 1674 C CA . SER A 1 228 ? -54.304 -20.839 12.656 1.00 54.24 ? 254 SER A CA 1 ATOM 1675 C C . SER A 1 228 ? -54.338 -22.233 13.265 1.00 53.54 ? 254 SER A C 1 ATOM 1676 O O . SER A 1 228 ? -55.011 -23.122 12.768 1.00 59.83 ? 254 SER A O 1 ATOM 1677 C CB . SER A 1 228 ? -55.280 -19.922 13.368 1.00 49.22 ? 254 SER A CB 1 ATOM 1678 O OG . SER A 1 228 ? -56.594 -20.280 13.009 1.00 48.49 ? 254 SER A OG 1 ATOM 1679 N N . GLY A 1 229 ? -53.614 -22.404 14.359 1.00 56.16 ? 255 GLY A N 1 ATOM 1680 C CA . GLY A 1 229 ? -53.580 -23.672 15.043 1.00 63.91 ? 255 GLY A CA 1 ATOM 1681 C C . GLY A 1 229 ? -52.780 -24.758 14.353 1.00 60.66 ? 255 GLY A C 1 ATOM 1682 O O . GLY A 1 229 ? -53.118 -25.916 14.440 1.00 77.08 ? 255 GLY A O 1 ATOM 1683 N N . ASN A 1 230 ? -51.792 -24.361 13.579 1.00 53.43 ? 256 ASN A N 1 ATOM 1684 C CA . ASN A 1 230 ? -50.929 -25.277 12.905 1.00 50.10 ? 256 ASN A CA 1 ATOM 1685 C C . ASN A 1 230 ? -49.592 -24.953 13.508 1.00 56.67 ? 256 ASN A C 1 ATOM 1686 O O . ASN A 1 230 ? -49.042 -23.901 13.246 1.00 61.74 ? 256 ASN A O 1 ATOM 1687 C CB . ASN A 1 230 ? -50.993 -25.045 11.444 1.00 51.11 ? 256 ASN A CB 1 ATOM 1688 C CG . ASN A 1 230 ? -52.341 -25.414 10.869 1.00 58.14 ? 256 ASN A CG 1 ATOM 1689 O OD1 . ASN A 1 230 ? -52.806 -26.514 11.064 1.00 59.24 ? 256 ASN A OD1 1 ATOM 1690 N ND2 . ASN A 1 230 ? -52.908 -24.541 10.050 1.00 64.83 ? 256 ASN A ND2 1 ATOM 1691 N N . CYS A 1 231 ? -49.055 -25.911 14.260 1.00 55.97 ? 257 CYS A N 1 ATOM 1692 C CA . CYS A 1 231 ? -47.845 -25.737 15.037 1.00 53.40 ? 257 CYS A CA 1 ATOM 1693 C C . CYS A 1 231 ? -48.223 -24.774 16.137 1.00 53.30 ? 257 CYS A C 1 ATOM 1694 O O . CYS A 1 231 ? -47.519 -23.789 16.374 1.00 54.86 ? 257 CYS A O 1 ATOM 1695 C CB . CYS A 1 231 ? -46.662 -25.247 14.248 1.00 53.19 ? 257 CYS A CB 1 ATOM 1696 S SG . CYS A 1 231 ? -46.110 -26.443 13.034 1.00 71.95 ? 257 CYS A SG 1 ATOM 1697 N N . PRO A 1 232 ? -49.291 -25.106 16.884 1.00 52.09 ? 258 PRO A N 1 ATOM 1698 C CA . PRO A 1 232 ? -49.657 -24.145 17.910 1.00 60.64 ? 258 PRO A CA 1 ATOM 1699 C C . PRO A 1 232 ? -48.719 -23.983 19.041 1.00 57.54 ? 258 PRO A C 1 ATOM 1700 O O . PRO A 1 232 ? -47.789 -24.765 19.226 1.00 69.93 ? 258 PRO A O 1 ATOM 1701 C CB . PRO A 1 232 ? -50.954 -24.741 18.505 1.00 60.57 ? 258 PRO A CB 1 ATOM 1702 C CG . PRO A 1 232 ? -50.749 -26.200 18.371 1.00 57.63 ? 258 PRO A CG 1 ATOM 1703 C CD . PRO A 1 232 ? -50.080 -26.353 17.017 1.00 56.09 ? 258 PRO A CD 1 ATOM 1704 N N . ARG A 1 233 ? -48.966 -22.916 19.771 1.00 59.41 ? 259 ARG A N 1 ATOM 1705 C CA . ARG A 1 233 ? -48.238 -22.602 20.962 1.00 64.21 ? 259 ARG A CA 1 ATOM 1706 C C . ARG A 1 233 ? -49.263 -22.983 22.011 1.00 72.66 ? 259 ARG A C 1 ATOM 1707 O O . ARG A 1 233 ? -50.262 -22.288 22.224 1.00 60.69 ? 259 ARG A O 1 ATOM 1708 C CB . ARG A 1 233 ? -47.820 -21.147 21.017 1.00 55.79 ? 259 ARG A CB 1 ATOM 1709 C CG . ARG A 1 233 ? -47.412 -20.726 22.395 1.00 56.73 ? 259 ARG A CG 1 ATOM 1710 C CD . ARG A 1 233 ? -46.689 -19.401 22.444 1.00 58.37 ? 259 ARG A CD 1 ATOM 1711 N NE . ARG A 1 233 ? -46.505 -18.990 23.828 1.00 68.25 ? 259 ARG A NE 1 ATOM 1712 C CZ . ARG A 1 233 ? -45.713 -18.006 24.221 1.00 77.65 ? 259 ARG A CZ 1 ATOM 1713 N NH1 . ARG A 1 233 ? -44.925 -17.408 23.356 1.00 88.26 ? 259 ARG A NH1 1 ATOM 1714 N NH2 . ARG A 1 233 ? -45.623 -17.700 25.503 1.00 85.31 ? 259 ARG A NH2 1 ATOM 1715 N N . CYS A 1 234 ? -49.113 -24.214 22.481 1.00 89.27 ? 260 CYS A N 1 ATOM 1716 C CA . CYS A 1 234 ? -50.021 -24.796 23.450 1.00 78.23 ? 260 CYS A CA 1 ATOM 1717 C C . CYS A 1 234 ? -49.930 -24.208 24.783 1.00 62.52 ? 260 CYS A C 1 ATOM 1718 O O . CYS A 1 234 ? -50.908 -24.177 25.492 1.00 61.26 ? 260 CYS A O 1 ATOM 1719 C CB . CYS A 1 234 ? -49.792 -26.290 23.529 1.00 70.52 ? 260 CYS A CB 1 ATOM 1720 S SG . CYS A 1 234 ? -50.377 -27.095 22.041 1.00 86.18 ? 260 CYS A SG 1 ATOM 1721 N N . PHE A 1 235 ? -48.757 -23.695 25.100 1.00 73.78 ? 261 PHE A N 1 ATOM 1722 C CA . PHE A 1 235 ? -48.502 -23.086 26.398 1.00 88.56 ? 261 PHE A CA 1 ATOM 1723 C C . PHE A 1 235 ? -49.613 -23.113 27.416 1.00 95.91 ? 261 PHE A C 1 ATOM 1724 O O . PHE A 1 235 ? -50.604 -22.405 27.276 1.00 103.35 ? 261 PHE A O 1 ATOM 1725 C CB . PHE A 1 235 ? -47.913 -21.679 26.239 1.00 83.39 ? 261 PHE A CB 1 ATOM 1726 C CG . PHE A 1 235 ? -46.398 -21.676 26.107 1.00 61.87 ? 261 PHE A CG 1 ATOM 1727 C CD1 . PHE A 1 235 ? -45.779 -22.314 25.088 1.00 51.36 ? 261 PHE A CD1 1 ATOM 1728 C CD2 . PHE A 1 235 ? -45.636 -20.998 27.005 1.00 55.51 ? 261 PHE A CD2 1 ATOM 1729 C CE1 . PHE A 1 235 ? -44.424 -22.317 24.990 1.00 61.69 ? 261 PHE A CE1 1 ATOM 1730 C CE2 . PHE A 1 235 ? -44.305 -20.951 26.875 1.00 49.08 ? 261 PHE A CE2 1 ATOM 1731 C CZ . PHE A 1 235 ? -43.683 -21.622 25.882 1.00 51.77 ? 261 PHE A CZ 1 ATOM 1732 N N . ASN A 1 236 ? -49.393 -23.933 28.455 1.00 102.83 ? 262 ASN A N 1 ATOM 1733 C CA . ASN A 1 236 ? -50.319 -24.114 29.592 1.00 118.09 ? 262 ASN A CA 1 ATOM 1734 C C . ASN A 1 236 ? -51.644 -24.761 29.257 1.00 114.64 ? 262 ASN A C 1 ATOM 1735 O O . ASN A 1 236 ? -52.671 -24.480 29.884 1.00 119.74 ? 262 ASN A O 1 ATOM 1736 C CB . ASN A 1 236 ? -50.529 -22.789 30.352 1.00 131.78 ? 262 ASN A CB 1 ATOM 1737 C CG . ASN A 1 236 ? -49.300 -22.355 31.140 1.00 132.19 ? 262 ASN A CG 1 ATOM 1738 O OD1 . ASN A 1 236 ? -48.937 -21.176 31.149 1.00 135.63 ? 262 ASN A OD1 1 ATOM 1739 N ND2 . ASN A 1 236 ? -48.628 -23.315 31.769 1.00 121.71 ? 262 ASN A ND2 1 ATOM 1740 N N . ALA A 1 237 ? -51.596 -25.698 28.324 1.00 107.44 ? 263 ALA A N 1 ATOM 1741 C CA . ALA A 1 237 ? -52.782 -26.409 27.901 1.00 105.76 ? 263 ALA A CA 1 ATOM 1742 C C . ALA A 1 237 ? -52.391 -27.834 27.585 1.00 107.50 ? 263 ALA A C 1 ATOM 1743 O O . ALA A 1 237 ? -51.271 -28.084 27.144 1.00 98.29 ? 263 ALA A O 1 ATOM 1744 C CB . ALA A 1 237 ? -53.389 -25.748 26.681 1.00 112.39 ? 263 ALA A CB 1 ATOM 1745 N N . PRO A 1 238 ? -53.326 -28.775 27.767 1.00 111.34 ? 264 PRO A N 1 ATOM 1746 C CA . PRO A 1 238 ? -53.037 -30.159 27.504 1.00 105.15 ? 264 PRO A CA 1 ATOM 1747 C C . PRO A 1 238 ? -53.684 -30.642 26.220 1.00 101.75 ? 264 PRO A C 1 ATOM 1748 O O . PRO A 1 238 ? -54.413 -29.894 25.565 1.00 106.27 ? 264 PRO A O 1 ATOM 1749 C CB . PRO A 1 238 ? -53.745 -30.841 28.664 1.00 116.87 ? 264 PRO A CB 1 ATOM 1750 C CG . PRO A 1 238 ? -55.008 -30.031 28.808 1.00 105.44 ? 264 PRO A CG 1 ATOM 1751 C CD . PRO A 1 238 ? -54.674 -28.626 28.351 1.00 105.93 ? 264 PRO A CD 1 ATOM 1752 N N . PHE A 1 239 ? -53.442 -31.907 25.899 1.00 106.48 ? 265 PHE A N 1 ATOM 1753 C CA . PHE A 1 239 ? -54.033 -32.557 24.732 1.00 103.27 ? 265 PHE A CA 1 ATOM 1754 C C . PHE A 1 239 ? -55.547 -32.249 24.851 1.00 103.76 ? 265 PHE A C 1 ATOM 1755 O O . PHE A 1 239 ? -56.077 -32.367 25.959 1.00 118.24 ? 265 PHE A O 1 ATOM 1756 C CB . PHE A 1 239 ? -53.763 -34.053 24.867 1.00 91.44 ? 265 PHE A CB 1 ATOM 1757 C CG . PHE A 1 239 ? -54.190 -34.868 23.691 1.00 96.02 ? 265 PHE A CG 1 ATOM 1758 C CD1 . PHE A 1 239 ? -53.260 -35.276 22.739 1.00 92.38 ? 265 PHE A CD1 1 ATOM 1759 C CD2 . PHE A 1 239 ? -55.511 -35.261 23.550 1.00 92.33 ? 265 PHE A CD2 1 ATOM 1760 C CE1 . PHE A 1 239 ? -53.646 -36.059 21.667 1.00 96.53 ? 265 PHE A CE1 1 ATOM 1761 C CE2 . PHE A 1 239 ? -55.908 -36.024 22.469 1.00 93.41 ? 265 PHE A CE2 1 ATOM 1762 C CZ . PHE A 1 239 ? -54.975 -36.428 21.529 1.00 98.33 ? 265 PHE A CZ 1 ATOM 1763 N N . PRO A 1 240 ? -56.292 -32.016 23.757 1.00 100.27 ? 266 PRO A N 1 ATOM 1764 C CA . PRO A 1 240 ? -55.854 -32.069 22.358 1.00 100.08 ? 266 PRO A CA 1 ATOM 1765 C C . PRO A 1 240 ? -54.952 -30.978 21.739 1.00 89.77 ? 266 PRO A C 1 ATOM 1766 O O . PRO A 1 240 ? -54.842 -30.932 20.523 1.00 93.77 ? 266 PRO A O 1 ATOM 1767 C CB . PRO A 1 240 ? -57.192 -32.119 21.594 1.00 90.37 ? 266 PRO A CB 1 ATOM 1768 C CG . PRO A 1 240 ? -58.236 -31.603 22.554 1.00 88.98 ? 266 PRO A CG 1 ATOM 1769 C CD . PRO A 1 240 ? -57.566 -31.293 23.867 1.00 95.93 ? 266 PRO A CD 1 ATOM 1770 N N . CYS A 1 241 ? -54.329 -30.111 22.525 1.00 76.63 ? 267 CYS A N 1 ATOM 1771 C CA . CYS A 1 241 ? -53.441 -29.124 21.937 1.00 81.44 ? 267 CYS A CA 1 ATOM 1772 C C . CYS A 1 241 ? -52.120 -29.838 21.716 1.00 74.55 ? 267 CYS A C 1 ATOM 1773 O O . CYS A 1 241 ? -51.478 -30.215 22.673 1.00 83.89 ? 267 CYS A O 1 ATOM 1774 C CB . CYS A 1 241 ? -53.237 -27.926 22.851 1.00 86.26 ? 267 CYS A CB 1 ATOM 1775 S SG . CYS A 1 241 ? -52.365 -26.586 22.010 1.00 80.38 ? 267 CYS A SG 1 ATOM 1776 N N . VAL A 1 242 ? -51.641 -29.877 20.475 1.00 83.39 ? 268 VAL A N 1 ATOM 1777 C CA . VAL A 1 242 ? -50.406 -30.603 20.160 1.00 75.39 ? 268 VAL A CA 1 ATOM 1778 C C . VAL A 1 242 ? -49.398 -29.837 19.291 1.00 67.47 ? 268 VAL A C 1 ATOM 1779 O O . VAL A 1 242 ? -49.611 -29.676 18.093 1.00 71.31 ? 268 VAL A O 1 ATOM 1780 C CB . VAL A 1 242 ? -50.780 -31.881 19.357 1.00 79.76 ? 268 VAL A CB 1 ATOM 1781 C CG1 . VAL A 1 242 ? -49.551 -32.743 19.075 1.00 71.93 ? 268 VAL A CG1 1 ATOM 1782 C CG2 . VAL A 1 242 ? -51.847 -32.677 20.091 1.00 76.72 ? 268 VAL A CG2 1 ATOM 1783 N N . PRO A 1 243 ? -48.227 -29.529 19.848 1.00 62.60 ? 269 PRO A N 1 ATOM 1784 C CA . PRO A 1 243 ? -47.171 -28.814 19.133 1.00 66.24 ? 269 PRO A CA 1 ATOM 1785 C C . PRO A 1 243 ? -46.416 -29.592 18.092 1.00 68.69 ? 269 PRO A C 1 ATOM 1786 O O . PRO A 1 243 ? -46.488 -30.806 18.050 1.00 90.94 ? 269 PRO A O 1 ATOM 1787 C CB . PRO A 1 243 ? -46.170 -28.477 20.235 1.00 54.64 ? 269 PRO A CB 1 ATOM 1788 C CG . PRO A 1 243 ? -46.996 -28.395 21.461 1.00 67.82 ? 269 PRO A CG 1 ATOM 1789 C CD . PRO A 1 243 ? -48.007 -29.495 21.298 1.00 69.23 ? 269 PRO A CD 1 ATOM 1790 N N . CYS A 1 244 ? -45.740 -28.858 17.219 1.00 76.98 ? 270 CYS A N 1 ATOM 1791 C CA . CYS A 1 244 ? -44.911 -29.452 16.210 1.00 75.51 ? 270 CYS A CA 1 ATOM 1792 C C . CYS A 1 244 ? -43.653 -29.866 16.971 1.00 76.96 ? 270 CYS A C 1 ATOM 1793 O O . CYS A 1 244 ? -43.310 -29.265 17.994 1.00 64.13 ? 270 CYS A O 1 ATOM 1794 C CB . CYS A 1 244 ? -44.638 -28.473 15.031 1.00 65.02 ? 270 CYS A CB 1 ATOM 1795 S SG . CYS A 1 244 ? -46.130 -28.286 13.994 1.00 96.96 ? 270 CYS A SG 1 ATOM 1796 N N . ASP A 1 245 ? -43.010 -30.933 16.523 1.00 85.47 ? 271 ASP A N 1 ATOM 1797 C CA . ASP A 1 245 ? -41.808 -31.419 17.186 1.00 89.27 ? 271 ASP A CA 1 ATOM 1798 C C . ASP A 1 245 ? -40.777 -30.328 17.402 1.00 80.35 ? 271 ASP A C 1 ATOM 1799 O O . ASP A 1 245 ? -40.385 -29.634 16.473 1.00 84.54 ? 271 ASP A O 1 ATOM 1800 C CB . ASP A 1 245 ? -41.188 -32.592 16.406 1.00 106.58 ? 271 ASP A CB 1 ATOM 1801 C CG . ASP A 1 245 ? -42.085 -33.841 16.395 1.00 109.63 ? 271 ASP A CG 1 ATOM 1802 O OD1 . ASP A 1 245 ? -43.114 -33.866 17.110 1.00 116.86 ? 271 ASP A OD1 1 ATOM 1803 O OD2 . ASP A 1 245 ? -41.736 -34.812 15.697 1.00 97.12 ? 271 ASP A OD2 1 ATOM 1804 N N . GLY A 1 246 ? -40.360 -30.176 18.651 1.00 84.80 ? 272 GLY A N 1 ATOM 1805 C CA . GLY A 1 246 ? -39.357 -29.185 19.025 1.00 90.28 ? 272 GLY A CA 1 ATOM 1806 C C . GLY A 1 246 ? -39.930 -27.798 19.105 1.00 100.10 ? 272 GLY A C 1 ATOM 1807 O O . GLY A 1 246 ? -39.195 -26.822 19.030 1.00 104.83 ? 272 GLY A O 1 ATOM 1808 N N . GLY A 1 247 ? -41.247 -27.711 19.272 1.00 109.67 ? 273 GLY A N 1 ATOM 1809 C CA . GLY A 1 247 ? -41.941 -26.420 19.339 1.00 110.86 ? 273 GLY A CA 1 ATOM 1810 C C . GLY A 1 247 ? -41.633 -25.502 18.153 1.00 99.34 ? 273 GLY A C 1 ATOM 1811 O O . GLY A 1 247 ? -41.533 -24.283 18.320 1.00 86.89 ? 273 GLY A O 1 ATOM 1812 N N . ALA A 1 248 ? -41.483 -26.088 16.962 1.00 85.66 ? 274 ALA A N 1 ATOM 1813 C CA . ALA A 1 248 ? -41.169 -25.325 15.741 1.00 84.32 ? 274 ALA A CA 1 ATOM 1814 C C . ALA A 1 248 ? -42.388 -24.616 15.168 1.00 74.73 ? 274 ALA A C 1 ATOM 1815 O O . ALA A 1 248 ? -43.507 -25.110 15.264 1.00 76.10 ? 274 ALA A O 1 ATOM 1816 C CB . ALA A 1 248 ? -40.587 -26.244 14.689 1.00 79.92 ? 274 ALA A CB 1 ATOM 1817 N N . SER A 1 249 ? -42.163 -23.505 14.481 1.00 72.33 ? 275 SER A N 1 ATOM 1818 C CA . SER A 1 249 ? -43.286 -22.785 13.915 1.00 67.39 ? 275 SER A CA 1 ATOM 1819 C C . SER A 1 249 ? -43.665 -23.394 12.622 1.00 56.88 ? 275 SER A C 1 ATOM 1820 O O . SER A 1 249 ? -42.917 -24.173 12.029 1.00 62.42 ? 275 SER A O 1 ATOM 1821 C CB . SER A 1 249 ? -42.950 -21.333 13.619 1.00 67.12 ? 275 SER A CB 1 ATOM 1822 O OG . SER A 1 249 ? -42.118 -21.222 12.490 1.00 64.63 ? 275 SER A OG 1 ATOM 1823 N N . ILE A 1 250 ? -44.835 -23.009 12.164 1.00 56.01 ? 276 ILE A N 1 ATOM 1824 C CA . ILE A 1 250 ? -45.314 -23.454 10.875 1.00 58.06 ? 276 ILE A CA 1 ATOM 1825 C C . ILE A 1 250 ? -44.219 -22.947 9.923 1.00 59.32 ? 276 ILE A C 1 ATOM 1826 O O . ILE A 1 250 ? -43.490 -21.991 10.239 1.00 50.82 ? 276 ILE A O 1 ATOM 1827 C CB . ILE A 1 250 ? -46.640 -22.785 10.530 1.00 56.13 ? 276 ILE A CB 1 ATOM 1828 C CG1 . ILE A 1 250 ? -47.252 -23.369 9.285 1.00 61.87 ? 276 ILE A CG1 1 ATOM 1829 C CG2 . ILE A 1 250 ? -46.443 -21.291 10.340 1.00 62.59 ? 276 ILE A CG2 1 ATOM 1830 C CD1 . ILE A 1 250 ? -48.619 -22.769 8.981 1.00 60.43 ? 276 ILE A CD1 1 ATOM 1831 N N . ASN A 1 251 ? -44.027 -23.654 8.829 1.00 58.76 ? 277 ASN A N 1 ATOM 1832 C CA . ASN A 1 251 ? -43.014 -23.290 7.863 1.00 65.01 ? 277 ASN A CA 1 ATOM 1833 C C . ASN A 1 251 ? -43.667 -22.856 6.584 1.00 65.68 ? 277 ASN A C 1 ATOM 1834 O O . ASN A 1 251 ? -44.271 -23.669 5.860 1.00 60.12 ? 277 ASN A O 1 ATOM 1835 C CB . ASN A 1 251 ? -42.076 -24.466 7.617 1.00 74.03 ? 277 ASN A CB 1 ATOM 1836 C CG . ASN A 1 251 ? -40.982 -24.138 6.633 1.00 71.14 ? 277 ASN A CG 1 ATOM 1837 O OD1 . ASN A 1 251 ? -39.809 -24.232 6.967 1.00 74.64 ? 277 ASN A OD1 1 ATOM 1838 N ND2 . ASN A 1 251 ? -41.353 -23.585 5.496 1.00 78.41 ? 277 ASN A ND2 1 ATOM 1839 N N . ILE A 1 252 ? -43.562 -21.565 6.304 1.00 67.94 ? 278 ILE A N 1 ATOM 1840 C CA . ILE A 1 252 ? -44.165 -21.016 5.104 1.00 69.75 ? 278 ILE A CA 1 ATOM 1841 C C . ILE A 1 252 ? -43.121 -20.552 4.106 1.00 61.17 ? 278 ILE A C 1 ATOM 1842 O O . ILE A 1 252 ? -42.259 -19.730 4.416 1.00 63.82 ? 278 ILE A O 1 ATOM 1843 C CB . ILE A 1 252 ? -45.115 -19.866 5.441 1.00 73.23 ? 278 ILE A CB 1 ATOM 1844 C CG1 . ILE A 1 252 ? -46.089 -20.321 6.544 1.00 75.07 ? 278 ILE A CG1 1 ATOM 1845 C CG2 . ILE A 1 252 ? -45.841 -19.432 4.176 1.00 68.75 ? 278 ILE A CG2 1 ATOM 1846 C CD1 . ILE A 1 252 ? -47.056 -19.253 7.020 1.00 78.44 ? 278 ILE A CD1 1 ATOM 1847 N N . ASP A 1 253 ? -43.243 -21.069 2.892 1.00 68.27 ? 279 ASP A N 1 ATOM 1848 C CA . ASP A 1 253 ? -42.344 -20.752 1.799 1.00 76.82 ? 279 ASP A CA 1 ATOM 1849 C C . ASP A 1 253 ? -42.432 -19.256 1.445 1.00 77.67 ? 279 ASP A C 1 ATOM 1850 O O . ASP A 1 253 ? -43.519 -18.658 1.456 1.00 67.56 ? 279 ASP A O 1 ATOM 1851 C CB . ASP A 1 253 ? -42.718 -21.623 0.584 1.00 85.86 ? 279 ASP A CB 1 ATOM 1852 C CG . ASP A 1 253 ? -41.751 -21.479 -0.570 1.00 92.29 ? 279 ASP A CG 1 ATOM 1853 O OD1 . ASP A 1 253 ? -40.625 -20.977 -0.364 1.00 89.48 ? 279 ASP A OD1 1 ATOM 1854 O OD2 . ASP A 1 253 ? -42.101 -21.936 -1.676 1.00 106.23 ? 279 ASP A OD2 1 ATOM 1855 N N . ARG A 1 254 ? -41.277 -18.674 1.125 1.00 79.19 ? 280 ARG A N 1 ATOM 1856 C CA . ARG A 1 254 ? -41.161 -17.257 0.756 1.00 75.89 ? 280 ARG A CA 1 ATOM 1857 C C . ARG A 1 254 ? -42.198 -16.858 -0.307 1.00 68.90 ? 280 ARG A C 1 ATOM 1858 O O . ARG A 1 254 ? -42.834 -15.803 -0.211 1.00 66.33 ? 280 ARG A O 1 ATOM 1859 C CB . ARG A 1 254 ? -39.768 -16.978 0.185 1.00 79.50 ? 280 ARG A CB 1 ATOM 1860 C CG . ARG A 1 254 ? -39.481 -15.503 0.004 1.00 98.57 ? 280 ARG A CG 1 ATOM 1861 C CD . ARG A 1 254 ? -38.236 -15.262 -0.825 1.00 108.00 ? 280 ARG A CD 1 ATOM 1862 N NE . ARG A 1 254 ? -37.862 -13.842 -0.880 1.00 116.61 ? 280 ARG A NE 1 ATOM 1863 C CZ . ARG A 1 254 ? -38.463 -12.911 -1.629 1.00 113.56 ? 280 ARG A CZ 1 ATOM 1864 N NH1 . ARG A 1 254 ? -39.620 -13.172 -2.249 1.00 89.77 ? 280 ARG A NH1 1 ATOM 1865 N NH2 . ARG A 1 254 ? -37.996 -11.660 -1.618 1.00 109.00 ? 280 ARG A NH2 1 ATOM 1866 N N . PHE A 1 255 ? -42.403 -17.721 -1.293 1.00 63.87 ? 281 PHE A N 1 ATOM 1867 C CA . PHE A 1 255 ? -43.353 -17.419 -2.366 1.00 65.73 ? 281 PHE A CA 1 ATOM 1868 C C . PHE A 1 255 ? -44.725 -18.006 -2.179 1.00 60.46 ? 281 PHE A C 1 ATOM 1869 O O . PHE A 1 255 ? -45.543 -17.948 -3.081 1.00 60.01 ? 281 PHE A O 1 ATOM 1870 C CB . PHE A 1 255 ? -42.791 -17.846 -3.731 1.00 66.34 ? 281 PHE A CB 1 ATOM 1871 C CG . PHE A 1 255 ? -41.473 -17.203 -4.059 1.00 73.83 ? 281 PHE A CG 1 ATOM 1872 C CD1 . PHE A 1 255 ? -41.416 -15.875 -4.456 1.00 71.42 ? 281 PHE A CD1 1 ATOM 1873 C CD2 . PHE A 1 255 ? -40.295 -17.932 -3.997 1.00 81.39 ? 281 PHE A CD2 1 ATOM 1874 C CE1 . PHE A 1 255 ? -40.204 -15.278 -4.742 1.00 78.19 ? 281 PHE A CE1 1 ATOM 1875 C CE2 . PHE A 1 255 ? -39.076 -17.339 -4.286 1.00 83.16 ? 281 PHE A CE2 1 ATOM 1876 C CZ . PHE A 1 255 ? -39.031 -16.011 -4.658 1.00 78.31 ? 281 PHE A CZ 1 ATOM 1877 N N . ALA A 1 256 ? -45.034 -18.433 -0.971 1.00 64.13 ? 282 ALA A N 1 ATOM 1878 C CA . ALA A 1 256 ? -46.328 -19.055 -0.710 1.00 62.44 ? 282 ALA A CA 1 ATOM 1879 C C . ALA A 1 256 ? -47.544 -18.186 -0.987 1.00 60.41 ? 282 ALA A C 1 ATOM 1880 O O . ALA A 1 256 ? -48.624 -18.704 -1.277 1.00 62.78 ? 282 ALA A O 1 ATOM 1881 C CB . ALA A 1 256 ? -46.366 -19.555 0.722 1.00 63.79 ? 282 ALA A CB 1 ATOM 1882 N N . PHE A 1 257 ? -47.396 -16.875 -0.830 1.00 67.47 ? 283 PHE A N 1 ATOM 1883 C CA . PHE A 1 257 ? -48.528 -15.964 -1.045 1.00 70.73 ? 283 PHE A CA 1 ATOM 1884 C C . PHE A 1 257 ? -48.329 -14.945 -2.176 1.00 64.39 ? 283 PHE A C 1 ATOM 1885 O O . PHE A 1 257 ? -49.131 -14.027 -2.290 1.00 55.92 ? 283 PHE A O 1 ATOM 1886 C CB . PHE A 1 257 ? -48.803 -15.131 0.218 1.00 68.24 ? 283 PHE A CB 1 ATOM 1887 C CG . PHE A 1 257 ? -48.973 -15.926 1.481 1.00 68.19 ? 283 PHE A CG 1 ATOM 1888 C CD1 . PHE A 1 257 ? -50.063 -16.748 1.659 1.00 82.72 ? 283 PHE A CD1 1 ATOM 1889 C CD2 . PHE A 1 257 ? -48.198 -15.628 2.583 1.00 74.76 ? 283 PHE A CD2 1 ATOM 1890 C CE1 . PHE A 1 257 ? -50.257 -17.417 2.852 1.00 77.92 ? 283 PHE A CE1 1 ATOM 1891 C CE2 . PHE A 1 257 ? -48.414 -16.246 3.797 1.00 74.53 ? 283 PHE A CE2 1 ATOM 1892 C CZ . PHE A 1 257 ? -49.445 -17.144 3.931 1.00 77.58 ? 283 PHE A CZ 1 ATOM 1893 N N . GLN A 1 258 ? -47.329 -15.133 -3.044 1.00 74.50 ? 284 GLN A N 1 ATOM 1894 C CA . GLN A 1 258 ? -47.055 -14.158 -4.110 1.00 63.77 ? 284 GLN A CA 1 ATOM 1895 C C . GLN A 1 258 ? -48.214 -13.850 -5.029 1.00 57.31 ? 284 GLN A C 1 ATOM 1896 O O . GLN A 1 258 ? -48.281 -12.758 -5.567 1.00 64.00 ? 284 GLN A O 1 ATOM 1897 C CB . GLN A 1 258 ? -45.868 -14.545 -4.959 1.00 65.58 ? 284 GLN A CB 1 ATOM 1898 C CG . GLN A 1 258 ? -46.076 -15.755 -5.831 1.00 78.58 ? 284 GLN A CG 1 ATOM 1899 C CD . GLN A 1 258 ? -44.923 -15.995 -6.801 1.00 92.72 ? 284 GLN A CD 1 ATOM 1900 O OE1 . GLN A 1 258 ? -44.869 -17.043 -7.452 1.00 104.63 ? 284 GLN A OE1 1 ATOM 1901 N NE2 . GLN A 1 258 ? -43.998 -15.023 -6.912 1.00 79.25 ? 284 GLN A NE2 1 ATOM 1902 N N . ASN A 1 259 ? -49.131 -14.790 -5.208 1.00 60.24 ? 285 ASN A N 1 ATOM 1903 C CA . ASN A 1 259 ? -50.282 -14.562 -6.079 1.00 56.93 ? 285 ASN A CA 1 ATOM 1904 C C . ASN A 1 259 ? -51.564 -14.261 -5.391 1.00 48.26 ? 285 ASN A C 1 ATOM 1905 O O . ASN A 1 259 ? -52.595 -14.210 -6.040 1.00 52.74 ? 285 ASN A O 1 ATOM 1906 C CB . ASN A 1 259 ? -50.533 -15.777 -6.970 1.00 71.18 ? 285 ASN A CB 1 ATOM 1907 C CG . ASN A 1 259 ? -49.485 -15.943 -8.039 1.00 86.02 ? 285 ASN A CG 1 ATOM 1908 O OD1 . ASN A 1 259 ? -48.714 -15.011 -8.325 1.00 81.09 ? 285 ASN A OD1 1 ATOM 1909 N ND2 . ASN A 1 259 ? -49.479 -17.126 -8.691 1.00 99.00 ? 285 ASN A ND2 1 ATOM 1910 N N . LEU A 1 260 ? -51.554 -14.147 -4.076 1.00 59.38 ? 286 LEU A N 1 ATOM 1911 C CA . LEU A 1 260 ? -52.802 -13.862 -3.342 1.00 66.10 ? 286 LEU A CA 1 ATOM 1912 C C . LEU A 1 260 ? -53.015 -12.363 -3.132 1.00 72.05 ? 286 LEU A C 1 ATOM 1913 O O . LEU A 1 260 ? -53.257 -11.910 -2.009 1.00 68.60 ? 286 LEU A O 1 ATOM 1914 C CB . LEU A 1 260 ? -52.778 -14.618 -2.016 1.00 76.35 ? 286 LEU A CB 1 ATOM 1915 C CG . LEU A 1 260 ? -53.166 -16.097 -2.038 1.00 66.83 ? 286 LEU A CG 1 ATOM 1916 C CD1 . LEU A 1 260 ? -52.660 -16.843 -3.250 1.00 86.18 ? 286 LEU A CD1 1 ATOM 1917 C CD2 . LEU A 1 260 ? -52.715 -16.730 -0.737 1.00 72.01 ? 286 LEU A CD2 1 ATOM 1918 N N . THR A 1 261 ? -53.097 -11.626 -4.243 1.00 58.84 ? 287 THR A N 1 ATOM 1919 C CA . THR A 1 261 ? -53.215 -10.185 -4.190 1.00 49.62 ? 287 THR A CA 1 ATOM 1920 C C . THR A 1 261 ? -54.541 -9.678 -3.651 1.00 51.84 ? 287 THR A C 1 ATOM 1921 O O . THR A 1 261 ? -54.635 -8.517 -3.256 1.00 54.91 ? 287 THR A O 1 ATOM 1922 C CB . THR A 1 261 ? -52.907 -9.551 -5.564 1.00 58.69 ? 287 THR A CB 1 ATOM 1923 O OG1 . THR A 1 261 ? -53.934 -9.872 -6.499 1.00 59.46 ? 287 THR A OG1 1 ATOM 1924 C CG2 . THR A 1 261 ? -51.591 -10.064 -6.093 1.00 66.79 ? 287 THR A CG2 1 ATOM 1925 N N . GLN A 1 262 ? -55.568 -10.522 -3.622 1.00 43.62 ? 288 GLN A N 1 ATOM 1926 C CA . GLN A 1 262 ? -56.882 -10.086 -3.099 1.00 50.15 ? 288 GLN A CA 1 ATOM 1927 C C . GLN A 1 262 ? -57.077 -10.380 -1.587 1.00 54.03 ? 288 GLN A C 1 ATOM 1928 O O . GLN A 1 262 ? -58.137 -10.140 -1.013 1.00 46.98 ? 288 GLN A O 1 ATOM 1929 C CB . GLN A 1 262 ? -57.955 -10.821 -3.877 1.00 53.10 ? 288 GLN A CB 1 ATOM 1930 C CG . GLN A 1 262 ? -57.785 -10.562 -5.341 1.00 68.45 ? 288 GLN A CG 1 ATOM 1931 C CD . GLN A 1 262 ? -57.749 -9.078 -5.584 1.00 72.46 ? 288 GLN A CD 1 ATOM 1932 O OE1 . GLN A 1 262 ? -58.630 -8.348 -5.111 1.00 72.13 ? 288 GLN A OE1 1 ATOM 1933 N NE2 . GLN A 1 262 ? -56.725 -8.610 -6.311 1.00 62.07 ? 288 GLN A NE2 1 ATOM 1934 N N . LEU A 1 263 ? -56.028 -10.832 -0.934 1.00 47.28 ? 289 LEU A N 1 ATOM 1935 C CA . LEU A 1 263 ? -56.147 -11.209 0.439 1.00 54.76 ? 289 LEU A CA 1 ATOM 1936 C C . LEU A 1 263 ? -56.427 -10.038 1.387 1.00 52.71 ? 289 LEU A C 1 ATOM 1937 O O . LEU A 1 263 ? -55.682 -9.046 1.432 1.00 55.40 ? 289 LEU A O 1 ATOM 1938 C CB . LEU A 1 263 ? -54.851 -11.941 0.839 1.00 57.31 ? 289 LEU A CB 1 ATOM 1939 C CG . LEU A 1 263 ? -54.941 -12.931 1.982 1.00 57.84 ? 289 LEU A CG 1 ATOM 1940 C CD1 . LEU A 1 263 ? -55.743 -14.121 1.510 1.00 58.99 ? 289 LEU A CD1 1 ATOM 1941 C CD2 . LEU A 1 263 ? -53.573 -13.395 2.393 1.00 60.34 ? 289 LEU A CD2 1 ATOM 1942 N N . ARG A 1 264 ? -57.542 -10.134 2.097 1.00 52.30 ? 290 ARG A N 1 ATOM 1943 C CA . ARG A 1 264 ? -57.932 -9.140 3.106 1.00 50.93 ? 290 ARG A CA 1 ATOM 1944 C C . ARG A 1 264 ? -57.727 -9.581 4.548 1.00 47.16 ? 290 ARG A C 1 ATOM 1945 O O . ARG A 1 264 ? -57.635 -8.746 5.433 1.00 50.37 ? 290 ARG A O 1 ATOM 1946 C CB . ARG A 1 264 ? -59.410 -8.801 3.044 1.00 50.87 ? 290 ARG A CB 1 ATOM 1947 C CG . ARG A 1 264 ? -59.823 -7.707 2.112 1.00 61.99 ? 290 ARG A CG 1 ATOM 1948 C CD . ARG A 1 264 ? -59.565 -8.028 0.688 1.00 67.69 ? 290 ARG A CD 1 ATOM 1949 N NE . ARG A 1 264 ? -60.015 -6.918 -0.116 1.00 70.19 ? 290 ARG A NE 1 ATOM 1950 C CZ . ARG A 1 264 ? -59.848 -6.846 -1.423 1.00 65.12 ? 290 ARG A CZ 1 ATOM 1951 N NH1 . ARG A 1 264 ? -59.237 -7.828 -2.059 1.00 60.08 ? 290 ARG A NH1 1 ATOM 1952 N NH2 . ARG A 1 264 ? -60.266 -5.775 -2.081 1.00 73.96 ? 290 ARG A NH2 1 ATOM 1953 N N . TYR A 1 265 ? -57.945 -10.860 4.800 1.00 57.24 ? 291 TYR A N 1 ATOM 1954 C CA . TYR A 1 265 ? -57.848 -11.415 6.151 1.00 51.00 ? 291 TYR A CA 1 ATOM 1955 C C . TYR A 1 265 ? -56.919 -12.579 6.176 1.00 43.68 ? 291 TYR A C 1 ATOM 1956 O O . TYR A 1 265 ? -57.113 -13.536 5.429 1.00 48.13 ? 291 TYR A O 1 ATOM 1957 C CB . TYR A 1 265 ? -59.192 -11.928 6.568 1.00 49.27 ? 291 TYR A CB 1 ATOM 1958 C CG . TYR A 1 265 ? -60.303 -10.913 6.578 1.00 53.08 ? 291 TYR A CG 1 ATOM 1959 C CD1 . TYR A 1 265 ? -61.077 -10.719 5.446 1.00 56.77 ? 291 TYR A CD1 1 ATOM 1960 C CD2 . TYR A 1 265 ? -60.707 -10.296 7.765 1.00 53.84 ? 291 TYR A CD2 1 ATOM 1961 C CE1 . TYR A 1 265 ? -62.166 -9.864 5.461 1.00 52.83 ? 291 TYR A CE1 1 ATOM 1962 C CE2 . TYR A 1 265 ? -61.771 -9.416 7.784 1.00 59.01 ? 291 TYR A CE2 1 ATOM 1963 C CZ . TYR A 1 265 ? -62.488 -9.200 6.616 1.00 61.07 ? 291 TYR A CZ 1 ATOM 1964 O OH . TYR A 1 265 ? -63.569 -8.366 6.593 1.00 75.73 ? 291 TYR A OH 1 ATOM 1965 N N . LEU A 1 266 ? -55.920 -12.502 7.041 1.00 36.59 ? 292 LEU A N 1 ATOM 1966 C CA . LEU A 1 266 ? -54.921 -13.563 7.185 1.00 45.19 ? 292 LEU A CA 1 ATOM 1967 C C . LEU A 1 266 ? -54.818 -13.925 8.669 1.00 50.51 ? 292 LEU A C 1 ATOM 1968 O O . LEU A 1 266 ? -54.509 -13.065 9.513 1.00 42.23 ? 292 LEU A O 1 ATOM 1969 C CB . LEU A 1 266 ? -53.564 -13.096 6.677 1.00 41.18 ? 292 LEU A CB 1 ATOM 1970 C CG . LEU A 1 266 ? -52.462 -14.137 6.774 1.00 47.80 ? 292 LEU A CG 1 ATOM 1971 C CD1 . LEU A 1 266 ? -52.862 -15.395 6.042 1.00 46.94 ? 292 LEU A CD1 1 ATOM 1972 C CD2 . LEU A 1 266 ? -51.134 -13.597 6.252 1.00 46.42 ? 292 LEU A CD2 1 ATOM 1973 N N . ASN A 1 267 ? -55.122 -15.177 8.994 1.00 47.63 ? 293 ASN A N 1 ATOM 1974 C CA . ASN A 1 267 ? -55.061 -15.617 10.383 1.00 42.60 ? 293 ASN A CA 1 ATOM 1975 C C . ASN A 1 267 ? -53.927 -16.595 10.605 1.00 48.02 ? 293 ASN A C 1 ATOM 1976 O O . ASN A 1 267 ? -53.907 -17.675 10.031 1.00 51.05 ? 293 ASN A O 1 ATOM 1977 C CB . ASN A 1 267 ? -56.381 -16.217 10.790 1.00 41.50 ? 293 ASN A CB 1 ATOM 1978 C CG . ASN A 1 267 ? -56.504 -16.373 12.277 1.00 43.51 ? 293 ASN A CG 1 ATOM 1979 O OD1 . ASN A 1 267 ? -55.504 -16.336 13.004 1.00 47.76 ? 293 ASN A OD1 1 ATOM 1980 N ND2 . ASN A 1 267 ? -57.729 -16.558 12.753 1.00 44.37 ? 293 ASN A ND2 1 ATOM 1981 N N . LEU A 1 268 ? -52.911 -16.135 11.321 1.00 46.22 ? 294 LEU A N 1 ATOM 1982 C CA . LEU A 1 268 ? -51.752 -16.945 11.636 1.00 47.26 ? 294 LEU A CA 1 ATOM 1983 C C . LEU A 1 268 ? -51.597 -17.065 13.150 1.00 50.15 ? 294 LEU A C 1 ATOM 1984 O O . LEU A 1 268 ? -50.478 -17.180 13.670 1.00 47.87 ? 294 LEU A O 1 ATOM 1985 C CB . LEU A 1 268 ? -50.487 -16.361 11.024 1.00 51.34 ? 294 LEU A CB 1 ATOM 1986 C CG . LEU A 1 268 ? -50.425 -16.391 9.500 1.00 58.99 ? 294 LEU A CG 1 ATOM 1987 C CD1 . LEU A 1 268 ? -49.208 -15.671 8.970 1.00 52.72 ? 294 LEU A CD1 1 ATOM 1988 C CD2 . LEU A 1 268 ? -50.427 -17.808 8.989 1.00 67.96 ? 294 LEU A CD2 1 ATOM 1989 N N . SER A 1 269 ? -52.723 -17.005 13.853 1.00 41.77 ? 295 SER A N 1 ATOM 1990 C CA . SER A 1 269 ? -52.700 -17.140 15.285 1.00 56.10 ? 295 SER A CA 1 ATOM 1991 C C . SER A 1 269 ? -52.308 -18.553 15.685 1.00 54.49 ? 295 SER A C 1 ATOM 1992 O O . SER A 1 269 ? -52.790 -19.506 15.098 1.00 56.84 ? 295 SER A O 1 ATOM 1993 C CB . SER A 1 269 ? -54.073 -16.885 15.870 1.00 51.39 ? 295 SER A CB 1 ATOM 1994 O OG . SER A 1 269 ? -54.472 -15.551 15.663 1.00 65.17 ? 295 SER A OG 1 ATOM 1995 N N . SER A 1 270 ? -51.369 -18.666 16.621 1.00 58.39 ? 296 SER A N 1 ATOM 1996 C CA . SER A 1 270 ? -50.943 -19.959 17.163 1.00 57.51 ? 296 SER A CA 1 ATOM 1997 C C . SER A 1 270 ? -50.349 -20.887 16.111 1.00 59.21 ? 296 SER A C 1 ATOM 1998 O O . SER A 1 270 ? -50.930 -21.948 15.772 1.00 51.00 ? 296 SER A O 1 ATOM 1999 C CB . SER A 1 270 ? -52.144 -20.626 17.856 1.00 56.09 ? 296 SER A CB 1 ATOM 2000 O OG . SER A 1 270 ? -51.750 -21.756 18.581 1.00 61.42 ? 296 SER A OG 1 ATOM 2001 N N . THR A 1 271 ? -49.229 -20.430 15.558 1.00 50.98 ? 297 THR A N 1 ATOM 2002 C CA . THR A 1 271 ? -48.466 -21.151 14.548 1.00 51.80 ? 297 THR A CA 1 ATOM 2003 C C . THR A 1 271 ? -47.013 -21.116 15.021 1.00 53.02 ? 297 THR A C 1 ATOM 2004 O O . THR A 1 271 ? -46.076 -21.447 14.302 1.00 58.91 ? 297 THR A O 1 ATOM 2005 C CB . THR A 1 271 ? -48.636 -20.495 13.157 1.00 52.92 ? 297 THR A CB 1 ATOM 2006 O OG1 . THR A 1 271 ? -48.341 -19.091 13.262 1.00 49.10 ? 297 THR A OG1 1 ATOM 2007 C CG2 . THR A 1 271 ? -50.080 -20.646 12.666 1.00 48.55 ? 297 THR A CG2 1 ATOM 2008 N N . SER A 1 272 ? -46.834 -20.626 16.232 1.00 54.49 ? 298 SER A N 1 ATOM 2009 C CA . SER A 1 272 ? -45.524 -20.571 16.865 1.00 59.69 ? 298 SER A CA 1 ATOM 2010 C C . SER A 1 272 ? -44.482 -19.837 16.081 1.00 55.91 ? 298 SER A C 1 ATOM 2011 O O . SER A 1 272 ? -43.292 -20.159 16.176 1.00 63.88 ? 298 SER A O 1 ATOM 2012 C CB . SER A 1 272 ? -45.045 -22.001 17.173 1.00 56.39 ? 298 SER A CB 1 ATOM 2013 O OG . SER A 1 272 ? -45.995 -22.659 18.005 1.00 52.85 ? 298 SER A OG 1 ATOM 2014 N N . LEU A 1 273 ? -44.905 -18.786 15.383 1.00 60.92 ? 299 LEU A N 1 ATOM 2015 C CA . LEU A 1 273 ? -43.978 -17.977 14.586 1.00 53.19 ? 299 LEU A CA 1 ATOM 2016 C C . LEU A 1 273 ? -42.978 -17.172 15.393 1.00 46.85 ? 299 LEU A C 1 ATOM 2017 O O . LEU A 1 273 ? -43.315 -16.545 16.387 1.00 53.45 ? 299 LEU A O 1 ATOM 2018 C CB . LEU A 1 273 ? -44.766 -17.011 13.718 1.00 60.16 ? 299 LEU A CB 1 ATOM 2019 C CG . LEU A 1 273 ? -45.473 -17.586 12.513 1.00 57.45 ? 299 LEU A CG 1 ATOM 2020 C CD1 . LEU A 1 273 ? -46.532 -16.634 12.018 1.00 57.25 ? 299 LEU A CD1 1 ATOM 2021 C CD2 . LEU A 1 273 ? -44.446 -17.898 11.446 1.00 55.92 ? 299 LEU A CD2 1 ATOM 2022 N N . ARG A 1 274 ? -41.740 -17.172 14.934 1.00 56.24 ? 300 ARG A N 1 ATOM 2023 C CA . ARG A 1 274 ? -40.671 -16.396 15.562 1.00 62.81 ? 300 ARG A CA 1 ATOM 2024 C C . ARG A 1 274 ? -40.244 -15.324 14.580 1.00 68.37 ? 300 ARG A C 1 ATOM 2025 O O . ARG A 1 274 ? -39.845 -14.228 14.980 1.00 67.56 ? 300 ARG A O 1 ATOM 2026 C CB . ARG A 1 274 ? -39.512 -17.291 15.997 1.00 70.17 ? 300 ARG A CB 1 ATOM 2027 C CG . ARG A 1 274 ? -39.880 -18.130 17.207 1.00 77.62 ? 300 ARG A CG 1 ATOM 2028 C CD . ARG A 1 274 ? -38.849 -19.163 17.609 1.00 87.35 ? 300 ARG A CD 1 ATOM 2029 N NE . ARG A 1 274 ? -39.289 -19.802 18.841 1.00 93.05 ? 300 ARG A NE 1 ATOM 2030 C CZ . ARG A 1 274 ? -40.223 -20.747 18.897 1.00 99.28 ? 300 ARG A CZ 1 ATOM 2031 N NH1 . ARG A 1 274 ? -40.556 -21.252 20.074 1.00 98.66 ? 300 ARG A NH1 1 ATOM 2032 N NH2 . ARG A 1 274 ? -40.853 -21.166 17.787 1.00 84.37 ? 300 ARG A NH2 1 ATOM 2033 N N . LYS A 1 275 ? -40.299 -15.659 13.292 1.00 75.97 ? 301 LYS A N 1 ATOM 2034 C CA . LYS A 1 275 ? -39.970 -14.706 12.244 1.00 82.27 ? 301 LYS A CA 1 ATOM 2035 C C . LYS A 1 275 ? -41.127 -14.583 11.274 1.00 73.28 ? 301 LYS A C 1 ATOM 2036 O O . LYS A 1 275 ? -41.792 -15.572 10.946 1.00 70.76 ? 301 LYS A O 1 ATOM 2037 C CB . LYS A 1 275 ? -38.686 -15.046 11.453 1.00 83.15 ? 301 LYS A CB 1 ATOM 2038 C CG . LYS A 1 275 ? -37.382 -15.003 12.250 1.00 106.54 ? 301 LYS A CG 1 ATOM 2039 C CD . LYS A 1 275 ? -36.143 -14.784 11.352 1.00 116.94 ? 301 LYS A CD 1 ATOM 2040 C CE . LYS A 1 275 ? -35.889 -15.840 10.279 1.00 109.28 ? 301 LYS A CE 1 ATOM 2041 N NZ . LYS A 1 275 ? -35.520 -17.168 10.834 1.00 112.99 ? 301 LYS A NZ 1 ATOM 2042 N N . ILE A 1 276 ? -41.409 -13.341 10.899 1.00 67.88 ? 302 ILE A N 1 ATOM 2043 C CA . ILE A 1 276 ? -42.455 -13.010 9.927 1.00 66.06 ? 302 ILE A CA 1 ATOM 2044 C C . ILE A 1 276 ? -41.678 -12.500 8.716 1.00 64.78 ? 302 ILE A C 1 ATOM 2045 O O . ILE A 1 276 ? -40.981 -11.487 8.821 1.00 65.86 ? 302 ILE A O 1 ATOM 2046 C CB . ILE A 1 276 ? -43.335 -11.841 10.393 1.00 59.97 ? 302 ILE A CB 1 ATOM 2047 C CG1 . ILE A 1 276 ? -44.046 -12.177 11.686 1.00 54.25 ? 302 ILE A CG1 1 ATOM 2048 C CG2 . ILE A 1 276 ? -44.361 -11.506 9.320 1.00 56.02 ? 302 ILE A CG2 1 ATOM 2049 C CD1 . ILE A 1 276 ? -45.061 -13.272 11.510 1.00 60.03 ? 302 ILE A CD1 1 ATOM 2050 N N . ASN A 1 277 ? -41.751 -13.212 7.594 1.00 58.69 ? 303 ASN A N 1 ATOM 2051 C CA . ASN A 1 277 ? -41.037 -12.793 6.395 1.00 56.22 ? 303 ASN A CA 1 ATOM 2052 C C . ASN A 1 277 ? -41.823 -11.662 5.718 1.00 52.49 ? 303 ASN A C 1 ATOM 2053 O O . ASN A 1 277 ? -42.938 -11.875 5.220 1.00 54.43 ? 303 ASN A O 1 ATOM 2054 C CB . ASN A 1 277 ? -40.878 -13.974 5.436 1.00 64.63 ? 303 ASN A CB 1 ATOM 2055 C CG . ASN A 1 277 ? -39.872 -13.693 4.329 1.00 64.26 ? 303 ASN A CG 1 ATOM 2056 O OD1 . ASN A 1 277 ? -39.353 -12.592 4.213 1.00 69.98 ? 303 ASN A OD1 1 ATOM 2057 N ND2 . ASN A 1 277 ? -39.569 -14.701 3.541 1.00 64.85 ? 303 ASN A ND2 1 ATOM 2058 N N . ALA A 1 278 ? -41.246 -10.467 5.706 1.00 50.82 ? 304 ALA A N 1 ATOM 2059 C CA . ALA A 1 278 ? -41.898 -9.299 5.101 1.00 53.31 ? 304 ALA A CA 1 ATOM 2060 C C . ALA A 1 278 ? -42.263 -9.552 3.682 1.00 52.75 ? 304 ALA A C 1 ATOM 2061 O O . ALA A 1 278 ? -43.326 -9.139 3.224 1.00 55.91 ? 304 ALA A O 1 ATOM 2062 C CB . ALA A 1 278 ? -41.016 -8.083 5.177 1.00 54.81 ? 304 ALA A CB 1 ATOM 2063 N N . ALA A 1 279 ? -41.457 -10.355 3.019 1.00 53.95 ? 305 ALA A N 1 ATOM 2064 C CA . ALA A 1 279 ? -41.719 -10.653 1.636 1.00 54.41 ? 305 ALA A CA 1 ATOM 2065 C C . ALA A 1 279 ? -43.035 -11.325 1.394 1.00 54.12 ? 305 ALA A C 1 ATOM 2066 O O . ALA A 1 279 ? -43.520 -11.311 0.260 1.00 56.51 ? 305 ALA A O 1 ATOM 2067 C CB . ALA A 1 279 ? -40.599 -11.484 1.058 1.00 57.93 ? 305 ALA A CB 1 ATOM 2068 N N . TRP A 1 280 ? -43.631 -11.935 2.419 1.00 64.33 ? 306 TRP A N 1 ATOM 2069 C CA . TRP A 1 280 ? -44.907 -12.626 2.183 1.00 60.07 ? 306 TRP A CA 1 ATOM 2070 C C . TRP A 1 280 ? -45.973 -11.643 1.815 1.00 53.68 ? 306 TRP A C 1 ATOM 2071 O O . TRP A 1 280 ? -47.033 -12.037 1.331 1.00 45.03 ? 306 TRP A O 1 ATOM 2072 C CB . TRP A 1 280 ? -45.449 -13.404 3.391 1.00 67.96 ? 306 TRP A CB 1 ATOM 2073 C CG . TRP A 1 280 ? -44.587 -14.450 3.999 1.00 81.43 ? 306 TRP A CG 1 ATOM 2074 C CD1 . TRP A 1 280 ? -43.935 -15.433 3.343 1.00 79.64 ? 306 TRP A CD1 1 ATOM 2075 C CD2 . TRP A 1 280 ? -44.647 -14.878 5.365 1.00 82.30 ? 306 TRP A CD2 1 ATOM 2076 N NE1 . TRP A 1 280 ? -43.377 -16.302 4.229 1.00 83.19 ? 306 TRP A NE1 1 ATOM 2077 C CE2 . TRP A 1 280 ? -43.832 -16.002 5.482 1.00 84.82 ? 306 TRP A CE2 1 ATOM 2078 C CE3 . TRP A 1 280 ? -45.272 -14.377 6.511 1.00 76.31 ? 306 TRP A CE3 1 ATOM 2079 C CZ2 . TRP A 1 280 ? -43.606 -16.633 6.695 1.00 77.44 ? 306 TRP A CZ2 1 ATOM 2080 C CZ3 . TRP A 1 280 ? -45.033 -14.984 7.704 1.00 78.97 ? 306 TRP A CZ3 1 ATOM 2081 C CH2 . TRP A 1 280 ? -44.194 -16.094 7.795 1.00 72.55 ? 306 TRP A CH2 1 ATOM 2082 N N . PHE A 1 281 ? -45.769 -10.394 2.213 1.00 50.28 ? 307 PHE A N 1 ATOM 2083 C CA . PHE A 1 281 ? -46.744 -9.345 1.943 1.00 60.19 ? 307 PHE A CA 1 ATOM 2084 C C . PHE A 1 281 ? -46.479 -8.445 0.721 1.00 56.07 ? 307 PHE A C 1 ATOM 2085 O O . PHE A 1 281 ? -47.253 -7.548 0.482 1.00 55.17 ? 307 PHE A O 1 ATOM 2086 C CB . PHE A 1 281 ? -46.898 -8.473 3.186 1.00 58.49 ? 307 PHE A CB 1 ATOM 2087 C CG . PHE A 1 281 ? -47.261 -9.251 4.398 1.00 51.52 ? 307 PHE A CG 1 ATOM 2088 C CD1 . PHE A 1 281 ? -48.546 -9.743 4.556 1.00 58.98 ? 307 PHE A CD1 1 ATOM 2089 C CD2 . PHE A 1 281 ? -46.330 -9.488 5.384 1.00 54.37 ? 307 PHE A CD2 1 ATOM 2090 C CE1 . PHE A 1 281 ? -48.875 -10.527 5.643 1.00 58.33 ? 307 PHE A CE1 1 ATOM 2091 C CE2 . PHE A 1 281 ? -46.645 -10.280 6.474 1.00 51.78 ? 307 PHE A CE2 1 ATOM 2092 C CZ . PHE A 1 281 ? -47.920 -10.804 6.597 1.00 54.19 ? 307 PHE A CZ 1 ATOM 2093 N N . LYS A 1 282 ? -45.414 -8.688 -0.045 1.00 64.54 ? 308 LYS A N 1 ATOM 2094 C CA . LYS A 1 282 ? -45.109 -7.842 -1.224 1.00 61.72 ? 308 LYS A CA 1 ATOM 2095 C C . LYS A 1 282 ? -46.270 -7.592 -2.142 1.00 58.60 ? 308 LYS A C 1 ATOM 2096 O O . LYS A 1 282 ? -46.423 -6.494 -2.665 1.00 54.11 ? 308 LYS A O 1 ATOM 2097 C CB . LYS A 1 282 ? -44.109 -8.475 -2.183 1.00 56.68 ? 308 LYS A CB 1 ATOM 2098 C CG . LYS A 1 282 ? -42.659 -8.491 -1.841 1.00 65.84 ? 308 LYS A CG 1 ATOM 2099 C CD . LYS A 1 282 ? -41.960 -8.835 -3.161 1.00 68.40 ? 308 LYS A CD 1 ATOM 2100 C CE . LYS A 1 282 ? -40.459 -8.622 -3.095 1.00 87.74 ? 308 LYS A CE 1 ATOM 2101 N NZ . LYS A 1 282 ? -39.873 -8.695 -4.456 1.00 89.90 ? 308 LYS A NZ 1 ATOM 2102 N N . ASN A 1 283 ? -47.032 -8.645 -2.397 1.00 44.54 ? 309 ASN A N 1 ATOM 2103 C CA . ASN A 1 283 ? -48.113 -8.580 -3.326 1.00 46.34 ? 309 ASN A CA 1 ATOM 2104 C C . ASN A 1 283 ? -49.426 -8.727 -2.721 1.00 44.02 ? 309 ASN A C 1 ATOM 2105 O O . ASN A 1 283 ? -50.320 -9.237 -3.369 1.00 46.38 ? 309 ASN A O 1 ATOM 2106 C CB . ASN A 1 283 ? -47.910 -9.701 -4.336 1.00 49.38 ? 309 ASN A CB 1 ATOM 2107 C CG . ASN A 1 283 ? -46.520 -9.649 -4.958 1.00 56.28 ? 309 ASN A CG 1 ATOM 2108 O OD1 . ASN A 1 283 ? -45.836 -8.631 -4.886 1.00 57.83 ? 309 ASN A OD1 1 ATOM 2109 N ND2 . ASN A 1 283 ? -46.086 -10.749 -5.516 1.00 57.65 ? 309 ASN A ND2 1 ATOM 2110 N N . MET A 1 284 ? -49.600 -8.155 -1.541 1.00 49.45 ? 310 MET A N 1 ATOM 2111 C CA . MET A 1 284 ? -50.856 -8.278 -0.831 1.00 55.59 ? 310 MET A CA 1 ATOM 2112 C C . MET A 1 284 ? -51.269 -6.890 -0.312 1.00 62.49 ? 310 MET A C 1 ATOM 2113 O O . MET A 1 284 ? -51.381 -6.669 0.880 1.00 60.62 ? 310 MET A O 1 ATOM 2114 C CB . MET A 1 284 ? -50.604 -9.265 0.294 1.00 64.35 ? 310 MET A CB 1 ATOM 2115 C CG . MET A 1 284 ? -51.825 -9.761 1.039 1.00 68.70 ? 310 MET A CG 1 ATOM 2116 S SD . MET A 1 284 ? -51.343 -10.888 2.366 1.00 61.18 ? 310 MET A SD 1 ATOM 2117 C CE . MET A 1 284 ? -50.557 -12.221 1.475 1.00 57.86 ? 310 MET A CE 1 ATOM 2118 N N . PRO A 1 285 ? -51.561 -5.958 -1.236 1.00 59.17 ? 311 PRO A N 1 ATOM 2119 C CA . PRO A 1 285 ? -51.922 -4.590 -0.896 1.00 45.13 ? 311 PRO A CA 1 ATOM 2120 C C . PRO A 1 285 ? -53.252 -4.363 -0.222 1.00 45.78 ? 311 PRO A C 1 ATOM 2121 O O . PRO A 1 285 ? -53.437 -3.303 0.378 1.00 44.60 ? 311 PRO A O 1 ATOM 2122 C CB . PRO A 1 285 ? -51.951 -3.906 -2.244 1.00 51.29 ? 311 PRO A CB 1 ATOM 2123 C CG . PRO A 1 285 ? -52.388 -4.988 -3.177 1.00 57.70 ? 311 PRO A CG 1 ATOM 2124 C CD . PRO A 1 285 ? -51.731 -6.229 -2.678 1.00 57.15 ? 311 PRO A CD 1 ATOM 2125 N N . HIS A 1 286 ? -54.157 -5.327 -0.260 1.00 45.18 ? 312 HIS A N 1 ATOM 2126 C CA . HIS A 1 286 ? -55.472 -5.138 0.361 1.00 45.71 ? 312 HIS A CA 1 ATOM 2127 C C . HIS A 1 286 ? -55.670 -5.715 1.772 1.00 44.08 ? 312 HIS A C 1 ATOM 2128 O O . HIS A 1 286 ? -56.758 -5.563 2.372 1.00 40.43 ? 312 HIS A O 1 ATOM 2129 C CB . HIS A 1 286 ? -56.533 -5.728 -0.548 1.00 51.48 ? 312 HIS A CB 1 ATOM 2130 C CG . HIS A 1 286 ? -56.496 -5.175 -1.949 1.00 66.16 ? 312 HIS A CG 1 ATOM 2131 N ND1 . HIS A 1 286 ? -57.147 -4.019 -2.314 1.00 59.21 ? 312 HIS A ND1 1 ATOM 2132 C CD2 . HIS A 1 286 ? -55.897 -5.640 -3.073 1.00 60.65 ? 312 HIS A CD2 1 ATOM 2133 C CE1 . HIS A 1 286 ? -56.919 -3.777 -3.590 1.00 59.37 ? 312 HIS A CE1 1 ATOM 2134 N NE2 . HIS A 1 286 ? -56.182 -4.757 -4.078 1.00 54.43 ? 312 HIS A NE2 1 ATOM 2135 N N . LEU A 1 287 ? -54.617 -6.245 2.363 1.00 42.21 ? 313 LEU A N 1 ATOM 2136 C CA . LEU A 1 287 ? -54.754 -6.861 3.685 1.00 46.63 ? 313 LEU A CA 1 ATOM 2137 C C . LEU A 1 287 ? -55.265 -5.905 4.738 1.00 39.81 ? 313 LEU A C 1 ATOM 2138 O O . LEU A 1 287 ? -54.567 -4.991 5.121 1.00 51.24 ? 313 LEU A O 1 ATOM 2139 C CB . LEU A 1 287 ? -53.431 -7.486 4.156 1.00 48.93 ? 313 LEU A CB 1 ATOM 2140 C CG . LEU A 1 287 ? -53.600 -8.455 5.350 1.00 47.80 ? 313 LEU A CG 1 ATOM 2141 C CD1 . LEU A 1 287 ? -54.420 -9.649 4.919 1.00 49.23 ? 313 LEU A CD1 1 ATOM 2142 C CD2 . LEU A 1 287 ? -52.278 -8.977 5.846 1.00 45.75 ? 313 LEU A CD2 1 ATOM 2143 N N . LYS A 1 288 ? -56.499 -6.128 5.184 1.00 47.04 ? 314 LYS A N 1 ATOM 2144 C CA . LYS A 1 288 ? -57.153 -5.325 6.224 1.00 47.78 ? 314 LYS A CA 1 ATOM 2145 C C . LYS A 1 288 ? -56.993 -5.848 7.659 1.00 47.60 ? 314 LYS A C 1 ATOM 2146 O O . LYS A 1 288 ? -57.102 -5.062 8.596 1.00 46.16 ? 314 LYS A O 1 ATOM 2147 C CB . LYS A 1 288 ? -58.695 -5.244 6.038 1.00 52.84 ? 314 LYS A CB 1 ATOM 2148 C CG . LYS A 1 288 ? -59.248 -4.404 4.907 1.00 68.89 ? 314 LYS A CG 1 ATOM 2149 C CD . LYS A 1 288 ? -60.711 -4.002 5.183 1.00 88.26 ? 314 LYS A CD 1 ATOM 2150 C CE . LYS A 1 288 ? -61.757 -5.099 5.065 1.00 97.29 ? 314 LYS A CE 1 ATOM 2151 N NZ . LYS A 1 288 ? -62.001 -5.437 3.633 1.00 108.87 ? 314 LYS A NZ 1 ATOM 2152 N N . VAL A 1 289 ? -56.951 -7.177 7.827 1.00 46.77 ? 315 VAL A N 1 ATOM 2153 C CA . VAL A 1 289 ? -56.881 -7.824 9.171 1.00 42.07 ? 315 VAL A CA 1 ATOM 2154 C C . VAL A 1 289 ? -55.810 -8.858 9.317 1.00 40.63 ? 315 VAL A C 1 ATOM 2155 O O . VAL A 1 289 ? -55.786 -9.827 8.574 1.00 43.02 ? 315 VAL A O 1 ATOM 2156 C CB . VAL A 1 289 ? -58.188 -8.554 9.463 1.00 43.10 ? 315 VAL A CB 1 ATOM 2157 C CG1 . VAL A 1 289 ? -58.144 -9.212 10.817 1.00 47.28 ? 315 VAL A CG1 1 ATOM 2158 C CG2 . VAL A 1 289 ? -59.366 -7.595 9.419 1.00 37.89 ? 315 VAL A CG2 1 ATOM 2159 N N . LEU A 1 290 ? -54.950 -8.702 10.312 1.00 38.39 ? 316 LEU A N 1 ATOM 2160 C CA . LEU A 1 290 ? -53.878 -9.671 10.493 1.00 45.01 ? 316 LEU A CA 1 ATOM 2161 C C . LEU A 1 290 ? -53.787 -10.161 11.956 1.00 48.63 ? 316 LEU A C 1 ATOM 2162 O O . LEU A 1 290 ? -53.471 -9.397 12.855 1.00 50.50 ? 316 LEU A O 1 ATOM 2163 C CB . LEU A 1 290 ? -52.572 -9.078 10.044 1.00 39.56 ? 316 LEU A CB 1 ATOM 2164 C CG . LEU A 1 290 ? -51.347 -9.929 10.287 1.00 45.33 ? 316 LEU A CG 1 ATOM 2165 C CD1 . LEU A 1 290 ? -51.393 -11.222 9.512 1.00 52.65 ? 316 LEU A CD1 1 ATOM 2166 C CD2 . LEU A 1 290 ? -50.111 -9.151 9.934 1.00 44.51 ? 316 LEU A CD2 1 ATOM 2167 N N . ASP A 1 291 ? -54.076 -11.448 12.151 1.00 52.64 ? 317 ASP A N 1 ATOM 2168 C CA . ASP A 1 291 ? -54.074 -12.120 13.467 1.00 45.56 ? 317 ASP A CA 1 ATOM 2169 C C . ASP A 1 291 ? -52.788 -12.898 13.689 1.00 47.14 ? 317 ASP A C 1 ATOM 2170 O O . ASP A 1 291 ? -52.507 -13.848 12.970 1.00 44.53 ? 317 ASP A O 1 ATOM 2171 C CB . ASP A 1 291 ? -55.267 -13.058 13.565 1.00 49.81 ? 317 ASP A CB 1 ATOM 2172 C CG . ASP A 1 291 ? -56.598 -12.327 13.820 1.00 62.33 ? 317 ASP A CG 1 ATOM 2173 O OD1 . ASP A 1 291 ? -57.613 -12.565 13.100 1.00 85.95 ? 317 ASP A OD1 1 ATOM 2174 O OD2 . ASP A 1 291 ? -56.630 -11.483 14.723 1.00 98.98 ? 317 ASP A OD2 1 ATOM 2175 N N . LEU A 1 292 ? -51.993 -12.450 14.656 1.00 40.34 ? 318 LEU A N 1 ATOM 2176 C CA . LEU A 1 292 ? -50.729 -13.084 15.001 1.00 48.22 ? 318 LEU A CA 1 ATOM 2177 C C . LEU A 1 292 ? -50.628 -13.359 16.538 1.00 46.26 ? 318 LEU A C 1 ATOM 2178 O O . LEU A 1 292 ? -49.552 -13.372 17.110 1.00 52.26 ? 318 LEU A O 1 ATOM 2179 C CB . LEU A 1 292 ? -49.578 -12.195 14.558 1.00 48.78 ? 318 LEU A CB 1 ATOM 2180 C CG . LEU A 1 292 ? -49.400 -12.038 13.065 1.00 49.23 ? 318 LEU A CG 1 ATOM 2181 C CD1 . LEU A 1 292 ? -48.481 -10.866 12.783 1.00 51.92 ? 318 LEU A CD1 1 ATOM 2182 C CD2 . LEU A 1 292 ? -48.853 -13.316 12.481 1.00 54.45 ? 318 LEU A CD2 1 ATOM 2183 N N . GLU A 1 293 ? -51.765 -13.614 17.154 1.00 44.13 ? 319 GLU A N 1 ATOM 2184 C CA . GLU A 1 293 ? -51.891 -13.917 18.584 1.00 51.52 ? 319 GLU A CA 1 ATOM 2185 C C . GLU A 1 293 ? -51.283 -15.315 18.860 1.00 56.39 ? 319 GLU A C 1 ATOM 2186 O O . GLU A 1 293 ? -51.309 -16.192 17.998 1.00 60.20 ? 319 GLU A O 1 ATOM 2187 C CB . GLU A 1 293 ? -53.380 -14.087 18.848 1.00 55.73 ? 319 GLU A CB 1 ATOM 2188 C CG . GLU A 1 293 ? -54.188 -13.065 18.061 1.00 83.40 ? 319 GLU A CG 1 ATOM 2189 C CD . GLU A 1 293 ? -55.571 -13.559 17.691 1.00 92.92 ? 319 GLU A CD 1 ATOM 2190 O OE1 . GLU A 1 293 ? -55.974 -13.380 16.501 1.00 66.78 ? 319 GLU A OE1 1 ATOM 2191 O OE2 . GLU A 1 293 ? -56.151 -14.296 18.510 1.00 109.78 ? 319 GLU A OE2 1 ATOM 2192 N N . PHE A 1 294 ? -50.781 -15.532 20.066 1.00 55.50 ? 320 PHE A N 1 ATOM 2193 C CA . PHE A 1 294 ? -50.258 -16.851 20.475 1.00 48.58 ? 320 PHE A CA 1 ATOM 2194 C C . PHE A 1 294 ? -49.112 -17.371 19.629 1.00 48.33 ? 320 PHE A C 1 ATOM 2195 O O . PHE A 1 294 ? -49.136 -18.492 19.141 1.00 48.39 ? 320 PHE A O 1 ATOM 2196 C CB . PHE A 1 294 ? -51.398 -17.882 20.510 1.00 39.66 ? 320 PHE A CB 1 ATOM 2197 C CG . PHE A 1 294 ? -52.629 -17.392 21.245 1.00 40.82 ? 320 PHE A CG 1 ATOM 2198 C CD1 . PHE A 1 294 ? -52.633 -17.272 22.624 1.00 53.08 ? 320 PHE A CD1 1 ATOM 2199 C CD2 . PHE A 1 294 ? -53.816 -17.225 20.586 1.00 41.14 ? 320 PHE A CD2 1 ATOM 2200 C CE1 . PHE A 1 294 ? -53.755 -16.828 23.293 1.00 48.63 ? 320 PHE A CE1 1 ATOM 2201 C CE2 . PHE A 1 294 ? -54.952 -16.773 21.248 1.00 43.01 ? 320 PHE A CE2 1 ATOM 2202 C CZ . PHE A 1 294 ? -54.916 -16.574 22.597 1.00 44.58 ? 320 PHE A CZ 1 ATOM 2203 N N . ASN A 1 295 ? -48.105 -16.533 19.499 1.00 45.82 ? 321 ASN A N 1 ATOM 2204 C CA . ASN A 1 295 ? -46.886 -16.828 18.764 1.00 52.12 ? 321 ASN A CA 1 ATOM 2205 C C . ASN A 1 295 ? -45.779 -16.321 19.668 1.00 50.47 ? 321 ASN A C 1 ATOM 2206 O O . ASN A 1 295 ? -46.058 -15.912 20.797 1.00 54.39 ? 321 ASN A O 1 ATOM 2207 C CB . ASN A 1 295 ? -46.872 -16.121 17.398 1.00 53.38 ? 321 ASN A CB 1 ATOM 2208 C CG . ASN A 1 295 ? -47.854 -16.741 16.417 1.00 56.34 ? 321 ASN A CG 1 ATOM 2209 O OD1 . ASN A 1 295 ? -47.733 -17.912 16.058 1.00 56.99 ? 321 ASN A OD1 1 ATOM 2210 N ND2 . ASN A 1 295 ? -48.738 -15.921 15.872 1.00 61.08 ? 321 ASN A ND2 1 ATOM 2211 N N . TYR A 1 296 ? -44.550 -16.320 19.170 1.00 52.15 ? 322 TYR A N 1 ATOM 2212 C CA . TYR A 1 296 ? -43.386 -15.867 19.928 1.00 60.51 ? 322 TYR A CA 1 ATOM 2213 C C . TYR A 1 296 ? -42.793 -14.675 19.187 1.00 62.51 ? 322 TYR A C 1 ATOM 2214 O O . TYR A 1 296 ? -41.606 -14.683 18.881 1.00 59.99 ? 322 TYR A O 1 ATOM 2215 C CB . TYR A 1 296 ? -42.356 -17.005 19.979 1.00 59.26 ? 322 TYR A CB 1 ATOM 2216 C CG . TYR A 1 296 ? -42.876 -18.285 20.587 1.00 59.53 ? 322 TYR A CG 1 ATOM 2217 C CD1 . TYR A 1 296 ? -42.805 -18.508 21.951 1.00 63.85 ? 322 TYR A CD1 1 ATOM 2218 C CD2 . TYR A 1 296 ? -43.379 -19.290 19.795 1.00 62.30 ? 322 TYR A CD2 1 ATOM 2219 C CE1 . TYR A 1 296 ? -43.284 -19.682 22.518 1.00 61.97 ? 322 TYR A CE1 1 ATOM 2220 C CE2 . TYR A 1 296 ? -43.856 -20.463 20.348 1.00 69.10 ? 322 TYR A CE2 1 ATOM 2221 C CZ . TYR A 1 296 ? -43.808 -20.655 21.718 1.00 67.53 ? 322 TYR A CZ 1 ATOM 2222 O OH . TYR A 1 296 ? -44.295 -21.826 22.274 1.00 52.87 ? 322 TYR A OH 1 ATOM 2223 N N . LEU A 1 297 ? -43.595 -13.617 18.997 1.00 59.43 ? 323 LEU A N 1 ATOM 2224 C CA . LEU A 1 297 ? -43.169 -12.429 18.223 1.00 54.73 ? 323 LEU A CA 1 ATOM 2225 C C . LEU A 1 297 ? -42.659 -11.162 18.903 1.00 56.82 ? 323 LEU A C 1 ATOM 2226 O O . LEU A 1 297 ? -42.635 -10.095 18.273 1.00 53.89 ? 323 LEU A O 1 ATOM 2227 C CB . LEU A 1 297 ? -44.319 -12.028 17.322 1.00 52.02 ? 323 LEU A CB 1 ATOM 2228 C CG . LEU A 1 297 ? -44.716 -13.137 16.364 1.00 49.92 ? 323 LEU A CG 1 ATOM 2229 C CD1 . LEU A 1 297 ? -46.052 -12.837 15.711 1.00 51.69 ? 323 LEU A CD1 1 ATOM 2230 C CD2 . LEU A 1 297 ? -43.623 -13.378 15.339 1.00 52.59 ? 323 LEU A CD2 1 ATOM 2231 N N . VAL A 1 298 ? -42.214 -11.247 20.144 1.00 52.60 ? 324 VAL A N 1 ATOM 2232 C CA . VAL A 1 298 ? -41.696 -10.054 20.816 1.00 56.11 ? 324 VAL A CA 1 ATOM 2233 C C . VAL A 1 298 ? -40.550 -9.411 19.994 1.00 56.28 ? 324 VAL A C 1 ATOM 2234 O O . VAL A 1 298 ? -40.390 -8.185 19.992 1.00 55.24 ? 324 VAL A O 1 ATOM 2235 C CB . VAL A 1 298 ? -41.192 -10.375 22.239 1.00 56.92 ? 324 VAL A CB 1 ATOM 2236 C CG1 . VAL A 1 298 ? -40.484 -9.175 22.851 1.00 56.04 ? 324 VAL A CG1 1 ATOM 2237 C CG2 . VAL A 1 298 ? -42.340 -10.815 23.119 1.00 55.78 ? 324 VAL A CG2 1 ATOM 2238 N N . GLY A 1 299 ? -39.746 -10.249 19.341 1.00 54.49 ? 325 GLY A N 1 ATOM 2239 C CA . GLY A 1 299 ? -38.618 -9.797 18.500 1.00 59.82 ? 325 GLY A CA 1 ATOM 2240 C C . GLY A 1 299 ? -39.118 -8.974 17.322 1.00 63.88 ? 325 GLY A C 1 ATOM 2241 O O . GLY A 1 299 ? -38.743 -7.796 17.148 1.00 66.10 ? 325 GLY A O 1 ATOM 2242 N N . GLU A 1 300 ? -39.990 -9.592 16.538 1.00 51.59 ? 326 GLU A N 1 ATOM 2243 C CA . GLU A 1 300 ? -40.609 -8.943 15.390 1.00 50.46 ? 326 GLU A CA 1 ATOM 2244 C C . GLU A 1 300 ? -41.308 -7.663 15.772 1.00 53.73 ? 326 GLU A C 1 ATOM 2245 O O . GLU A 1 300 ? -41.291 -6.706 15.016 1.00 64.47 ? 326 GLU A O 1 ATOM 2246 C CB . GLU A 1 300 ? -41.626 -9.872 14.765 1.00 51.59 ? 326 GLU A CB 1 ATOM 2247 C CG . GLU A 1 300 ? -41.002 -11.012 13.991 1.00 59.79 ? 326 GLU A CG 1 ATOM 2248 C CD . GLU A 1 300 ? -40.297 -10.502 12.761 1.00 60.73 ? 326 GLU A CD 1 ATOM 2249 O OE1 . GLU A 1 300 ? -40.305 -9.262 12.572 1.00 66.74 ? 326 GLU A OE1 1 ATOM 2250 O OE2 . GLU A 1 300 ? -39.783 -11.325 11.977 1.00 64.75 ? 326 GLU A OE2 1 ATOM 2251 N N . ILE A 1 301 ? -41.955 -7.656 16.930 1.00 49.14 ? 327 ILE A N 1 ATOM 2252 C CA . ILE A 1 301 ? -42.644 -6.470 17.395 1.00 47.36 ? 327 ILE A CA 1 ATOM 2253 C C . ILE A 1 301 ? -41.655 -5.348 17.612 1.00 52.62 ? 327 ILE A C 1 ATOM 2254 O O . ILE A 1 301 ? -41.974 -4.183 17.375 1.00 55.77 ? 327 ILE A O 1 ATOM 2255 C CB . ILE A 1 301 ? -43.394 -6.742 18.680 1.00 47.58 ? 327 ILE A CB 1 ATOM 2256 C CG1 . ILE A 1 301 ? -44.470 -7.788 18.404 1.00 48.77 ? 327 ILE A CG1 1 ATOM 2257 C CG2 . ILE A 1 301 ? -44.015 -5.460 19.235 1.00 46.49 ? 327 ILE A CG2 1 ATOM 2258 C CD1 . ILE A 1 301 ? -45.242 -8.210 19.640 1.00 50.51 ? 327 ILE A CD1 1 ATOM 2259 N N . ALA A 1 302 ? -40.426 -5.699 17.982 1.00 53.11 ? 328 ALA A N 1 ATOM 2260 C CA . ALA A 1 302 ? -39.398 -4.682 18.194 1.00 53.32 ? 328 ALA A CA 1 ATOM 2261 C C . ALA A 1 302 ? -38.693 -4.232 16.901 1.00 58.21 ? 328 ALA A C 1 ATOM 2262 O O . ALA A 1 302 ? -38.333 -3.075 16.786 1.00 49.98 ? 328 ALA A O 1 ATOM 2263 C CB . ALA A 1 302 ? -38.376 -5.171 19.172 1.00 52.14 ? 328 ALA A CB 1 ATOM 2264 N N . SER A 1 303 ? -38.481 -5.143 15.953 1.00 60.76 ? 329 SER A N 1 ATOM 2265 C CA . SER A 1 303 ? -37.808 -4.797 14.705 1.00 69.35 ? 329 SER A CA 1 ATOM 2266 C C . SER A 1 303 ? -38.428 -5.516 13.521 1.00 70.91 ? 329 SER A C 1 ATOM 2267 O O . SER A 1 303 ? -37.737 -6.191 12.783 1.00 87.79 ? 329 SER A O 1 ATOM 2268 C CB . SER A 1 303 ? -36.362 -5.249 14.786 1.00 73.60 ? 329 SER A CB 1 ATOM 2269 O OG . SER A 1 303 ? -36.305 -6.672 14.818 1.00 74.04 ? 329 SER A OG 1 ATOM 2270 N N . GLY A 1 304 ? -39.712 -5.340 13.307 1.00 75.01 ? 330 GLY A N 1 ATOM 2271 C CA . GLY A 1 304 ? -40.386 -6.015 12.210 1.00 71.10 ? 330 GLY A CA 1 ATOM 2272 C C . GLY A 1 304 ? -40.530 -5.244 10.901 1.00 67.90 ? 330 GLY A C 1 ATOM 2273 O O . GLY A 1 304 ? -41.317 -4.281 10.758 1.00 60.29 ? 330 GLY A O 1 ATOM 2274 N N . ALA A 1 305 ? -39.857 -5.776 9.904 1.00 61.88 ? 331 ALA A N 1 ATOM 2275 C CA . ALA A 1 305 ? -39.870 -5.203 8.592 1.00 56.16 ? 331 ALA A CA 1 ATOM 2276 C C . ALA A 1 305 ? -41.252 -5.378 7.942 1.00 59.48 ? 331 ALA A C 1 ATOM 2277 O O . ALA A 1 305 ? -41.670 -4.546 7.143 1.00 59.28 ? 331 ALA A O 1 ATOM 2278 C CB . ALA A 1 305 ? -38.794 -5.872 7.757 1.00 47.25 ? 331 ALA A CB 1 ATOM 2279 N N . PHE A 1 306 ? -41.983 -6.416 8.360 1.00 58.94 ? 332 PHE A N 1 ATOM 2280 C CA . PHE A 1 306 ? -43.295 -6.715 7.800 1.00 52.38 ? 332 PHE A CA 1 ATOM 2281 C C . PHE A 1 306 ? -44.260 -5.554 8.074 1.00 51.74 ? 332 PHE A C 1 ATOM 2282 O O . PHE A 1 306 ? -45.288 -5.420 7.429 1.00 54.21 ? 332 PHE A O 1 ATOM 2283 C CB . PHE A 1 306 ? -43.861 -8.054 8.374 1.00 55.59 ? 332 PHE A CB 1 ATOM 2284 C CG . PHE A 1 306 ? -44.495 -7.935 9.747 1.00 46.44 ? 332 PHE A CG 1 ATOM 2285 C CD1 . PHE A 1 306 ? -43.738 -7.967 10.887 1.00 53.50 ? 332 PHE A CD1 1 ATOM 2286 C CD2 . PHE A 1 306 ? -45.861 -7.834 9.870 1.00 52.78 ? 332 PHE A CD2 1 ATOM 2287 C CE1 . PHE A 1 306 ? -44.310 -7.816 12.125 1.00 50.49 ? 332 PHE A CE1 1 ATOM 2288 C CE2 . PHE A 1 306 ? -46.450 -7.683 11.104 1.00 57.72 ? 332 PHE A CE2 1 ATOM 2289 C CZ . PHE A 1 306 ? -45.668 -7.668 12.236 1.00 55.24 ? 332 PHE A CZ 1 ATOM 2290 N N . LEU A 1 307 ? -43.933 -4.739 9.060 1.00 56.33 ? 333 LEU A N 1 ATOM 2291 C CA . LEU A 1 307 ? -44.771 -3.591 9.417 1.00 62.59 ? 333 LEU A CA 1 ATOM 2292 C C . LEU A 1 307 ? -44.775 -2.506 8.334 1.00 58.16 ? 333 LEU A C 1 ATOM 2293 O O . LEU A 1 307 ? -45.703 -1.717 8.222 1.00 64.05 ? 333 LEU A O 1 ATOM 2294 C CB . LEU A 1 307 ? -44.264 -3.005 10.742 1.00 61.40 ? 333 LEU A CB 1 ATOM 2295 C CG . LEU A 1 307 ? -44.477 -3.917 11.962 1.00 60.56 ? 333 LEU A CG 1 ATOM 2296 C CD1 . LEU A 1 307 ? -43.655 -3.518 13.173 1.00 65.82 ? 333 LEU A CD1 1 ATOM 2297 C CD2 . LEU A 1 307 ? -45.953 -4.013 12.313 1.00 59.49 ? 333 LEU A CD2 1 ATOM 2298 N N . THR A 1 308 ? -43.748 -2.495 7.510 1.00 57.88 ? 334 THR A N 1 ATOM 2299 C CA . THR A 1 308 ? -43.657 -1.488 6.465 1.00 65.54 ? 334 THR A CA 1 ATOM 2300 C C . THR A 1 308 ? -44.454 -1.883 5.243 1.00 55.82 ? 334 THR A C 1 ATOM 2301 O O . THR A 1 308 ? -44.705 -1.055 4.413 1.00 60.79 ? 334 THR A O 1 ATOM 2302 C CB . THR A 1 308 ? -42.188 -1.234 6.031 1.00 55.11 ? 334 THR A CB 1 ATOM 2303 O OG1 . THR A 1 308 ? -41.625 -2.441 5.516 1.00 60.25 ? 334 THR A OG1 1 ATOM 2304 C CG2 . THR A 1 308 ? -41.333 -0.757 7.205 1.00 55.08 ? 334 THR A CG2 1 ATOM 2305 N N . MET A 1 309 ? -44.966 -3.105 5.220 1.00 56.97 ? 335 MET A N 1 ATOM 2306 C CA . MET A 1 309 ? -45.708 -3.622 4.083 1.00 51.06 ? 335 MET A CA 1 ATOM 2307 C C . MET A 1 309 ? -47.190 -3.575 4.279 1.00 47.71 ? 335 MET A C 1 ATOM 2308 O O . MET A 1 309 ? -47.917 -4.121 3.456 1.00 56.09 ? 335 MET A O 1 ATOM 2309 C CB . MET A 1 309 ? -45.380 -5.116 3.926 1.00 50.02 ? 335 MET A CB 1 ATOM 2310 C CG . MET A 1 309 ? -43.904 -5.461 3.897 1.00 60.82 ? 335 MET A CG 1 ATOM 2311 S SD . MET A 1 309 ? -42.962 -4.902 2.464 1.00 62.26 ? 335 MET A SD 1 ATOM 2312 C CE . MET A 1 309 ? -43.676 -5.924 1.205 1.00 60.20 ? 335 MET A CE 1 ATOM 2313 N N . LEU A 1 310 ? -47.672 -2.891 5.308 1.00 52.81 ? 336 LEU A N 1 ATOM 2314 C CA . LEU A 1 310 ? -49.130 -2.902 5.592 1.00 46.21 ? 336 LEU A CA 1 ATOM 2315 C C . LEU A 1 310 ? -49.835 -1.567 5.868 1.00 47.61 ? 336 LEU A C 1 ATOM 2316 O O . LEU A 1 310 ? -50.646 -1.455 6.783 1.00 46.18 ? 336 LEU A O 1 ATOM 2317 C CB . LEU A 1 310 ? -49.303 -3.806 6.797 1.00 52.53 ? 336 LEU A CB 1 ATOM 2318 C CG . LEU A 1 310 ? -48.745 -5.229 6.596 1.00 53.13 ? 336 LEU A CG 1 ATOM 2319 C CD1 . LEU A 1 310 ? -48.602 -6.006 7.902 1.00 52.80 ? 336 LEU A CD1 1 ATOM 2320 C CD2 . LEU A 1 310 ? -49.614 -5.977 5.608 1.00 51.28 ? 336 LEU A CD2 1 ATOM 2321 N N . PRO A 1 311 ? -49.624 -0.577 5.002 1.00 55.23 ? 337 PRO A N 1 ATOM 2322 C CA . PRO A 1 311 ? -50.225 0.767 5.123 1.00 44.56 ? 337 PRO A CA 1 ATOM 2323 C C . PRO A 1 311 ? -51.745 0.764 5.066 1.00 40.85 ? 337 PRO A C 1 ATOM 2324 O O . PRO A 1 311 ? -52.413 1.724 5.501 1.00 43.15 ? 337 PRO A O 1 ATOM 2325 C CB . PRO A 1 311 ? -49.683 1.458 3.902 1.00 45.15 ? 337 PRO A CB 1 ATOM 2326 C CG . PRO A 1 311 ? -49.603 0.352 2.924 1.00 46.93 ? 337 PRO A CG 1 ATOM 2327 C CD . PRO A 1 311 ? -48.999 -0.758 3.687 1.00 45.78 ? 337 PRO A CD 1 ATOM 2328 N N . ARG A 1 312 ? -52.304 -0.330 4.608 1.00 41.94 ? 338 ARG A N 1 ATOM 2329 C CA . ARG A 1 312 ? -53.732 -0.419 4.509 1.00 46.06 ? 338 ARG A CA 1 ATOM 2330 C C . ARG A 1 312 ? -54.351 -1.334 5.640 1.00 47.31 ? 338 ARG A C 1 ATOM 2331 O O . ARG A 1 312 ? -55.565 -1.501 5.716 1.00 40.87 ? 338 ARG A O 1 ATOM 2332 C CB . ARG A 1 312 ? -54.031 -0.979 3.117 1.00 51.72 ? 338 ARG A CB 1 ATOM 2333 C CG . ARG A 1 312 ? -55.351 -0.536 2.519 1.00 63.65 ? 338 ARG A CG 1 ATOM 2334 C CD . ARG A 1 312 ? -56.493 -0.925 3.404 1.00 74.35 ? 338 ARG A CD 1 ATOM 2335 N NE . ARG A 1 312 ? -57.772 -0.364 3.019 1.00 72.05 ? 338 ARG A NE 1 ATOM 2336 C CZ . ARG A 1 312 ? -58.850 -0.543 3.759 1.00 81.97 ? 338 ARG A CZ 1 ATOM 2337 N NH1 . ARG A 1 312 ? -58.726 -1.200 4.892 1.00 85.24 ? 338 ARG A NH1 1 ATOM 2338 N NH2 . ARG A 1 312 ? -60.027 -0.031 3.423 1.00 103.75 ? 338 ARG A NH2 1 ATOM 2339 N N . LEU A 1 313 ? -53.538 -1.868 6.552 1.00 46.82 ? 339 LEU A N 1 ATOM 2340 C CA . LEU A 1 313 ? -54.069 -2.744 7.623 1.00 38.55 ? 339 LEU A CA 1 ATOM 2341 C C . LEU A 1 313 ? -54.942 -1.983 8.653 1.00 37.43 ? 339 LEU A C 1 ATOM 2342 O O . LEU A 1 313 ? -54.608 -0.903 9.087 1.00 44.64 ? 339 LEU A O 1 ATOM 2343 C CB . LEU A 1 313 ? -52.909 -3.369 8.363 1.00 43.58 ? 339 LEU A CB 1 ATOM 2344 C CG . LEU A 1 313 ? -53.189 -4.576 9.273 1.00 52.26 ? 339 LEU A CG 1 ATOM 2345 C CD1 . LEU A 1 313 ? -53.522 -5.769 8.385 1.00 45.62 ? 339 LEU A CD1 1 ATOM 2346 C CD2 . LEU A 1 313 ? -51.982 -4.921 10.136 1.00 42.78 ? 339 LEU A CD2 1 ATOM 2347 N N . GLU A 1 314 ? -56.090 -2.529 8.989 1.00 39.58 ? 340 GLU A N 1 ATOM 2348 C CA . GLU A 1 314 ? -56.961 -1.922 9.963 1.00 45.20 ? 340 GLU A CA 1 ATOM 2349 C C . GLU A 1 314 ? -56.910 -2.578 11.342 1.00 46.95 ? 340 GLU A C 1 ATOM 2350 O O . GLU A 1 314 ? -57.018 -1.895 12.340 1.00 49.06 ? 340 GLU A O 1 ATOM 2351 C CB . GLU A 1 314 ? -58.385 -1.959 9.499 1.00 49.84 ? 340 GLU A CB 1 ATOM 2352 C CG . GLU A 1 314 ? -58.633 -1.139 8.265 1.00 55.25 ? 340 GLU A CG 1 ATOM 2353 C CD . GLU A 1 314 ? -60.079 -1.181 7.822 1.00 53.07 ? 340 GLU A CD 1 ATOM 2354 O OE1 . GLU A 1 314 ? -60.943 -1.646 8.581 1.00 67.40 ? 340 GLU A OE1 1 ATOM 2355 O OE2 . GLU A 1 314 ? -60.358 -0.700 6.716 1.00 65.73 ? 340 GLU A OE2 1 ATOM 2356 N N . ILE A 1 315 ? -56.715 -3.890 11.393 1.00 47.63 ? 341 ILE A N 1 ATOM 2357 C CA . ILE A 1 315 ? -56.686 -4.603 12.660 1.00 40.34 ? 341 ILE A CA 1 ATOM 2358 C C . ILE A 1 315 ? -55.510 -5.497 12.767 1.00 39.40 ? 341 ILE A C 1 ATOM 2359 O O . ILE A 1 315 ? -55.299 -6.339 11.899 1.00 40.37 ? 341 ILE A O 1 ATOM 2360 C CB . ILE A 1 315 ? -57.928 -5.461 12.794 1.00 43.83 ? 341 ILE A CB 1 ATOM 2361 C CG1 . ILE A 1 315 ? -59.148 -4.560 12.764 1.00 37.78 ? 341 ILE A CG1 1 ATOM 2362 C CG2 . ILE A 1 315 ? -57.919 -6.193 14.118 1.00 42.72 ? 341 ILE A CG2 1 ATOM 2363 C CD1 . ILE A 1 315 ? -60.425 -5.311 12.892 1.00 40.80 ? 341 ILE A CD1 1 ATOM 2364 N N . LEU A 1 316 ? -54.693 -5.260 13.788 1.00 35.34 ? 342 LEU A N 1 ATOM 2365 C CA . LEU A 1 316 ? -53.493 -6.074 14.019 1.00 38.74 ? 342 LEU A CA 1 ATOM 2366 C C . LEU A 1 316 ? -53.583 -6.633 15.431 1.00 47.96 ? 342 LEU A C 1 ATOM 2367 O O . LEU A 1 316 ? -53.749 -5.857 16.413 1.00 41.98 ? 342 LEU A O 1 ATOM 2368 C CB . LEU A 1 316 ? -52.231 -5.246 13.907 1.00 39.04 ? 342 LEU A CB 1 ATOM 2369 C CG . LEU A 1 316 ? -50.910 -5.973 14.160 1.00 40.94 ? 342 LEU A CG 1 ATOM 2370 C CD1 . LEU A 1 316 ? -50.717 -7.120 13.217 1.00 40.10 ? 342 LEU A CD1 1 ATOM 2371 C CD2 . LEU A 1 316 ? -49.751 -5.022 14.005 1.00 49.05 ? 342 LEU A CD2 1 ATOM 2372 N N . ASP A 1 317 ? -53.589 -7.969 15.528 1.00 46.13 ? 343 ASP A N 1 ATOM 2373 C CA . ASP A 1 317 ? -53.683 -8.632 16.836 1.00 47.71 ? 343 ASP A CA 1 ATOM 2374 C C . ASP A 1 317 ? -52.380 -9.306 17.134 1.00 43.08 ? 343 ASP A C 1 ATOM 2375 O O . ASP A 1 317 ? -51.958 -10.202 16.411 1.00 40.98 ? 343 ASP A O 1 ATOM 2376 C CB . ASP A 1 317 ? -54.820 -9.630 16.873 1.00 42.64 ? 343 ASP A CB 1 ATOM 2377 C CG . ASP A 1 317 ? -55.159 -10.090 18.289 1.00 53.81 ? 343 ASP A CG 1 ATOM 2378 O OD1 . ASP A 1 317 ? -54.297 -10.034 19.224 1.00 51.46 ? 343 ASP A OD1 1 ATOM 2379 O OD2 . ASP A 1 317 ? -56.300 -10.564 18.451 1.00 54.84 ? 343 ASP A OD2 1 ATOM 2380 N N . LEU A 1 318 ? -51.700 -8.802 18.149 1.00 40.02 ? 344 LEU A N 1 ATOM 2381 C CA . LEU A 1 318 ? -50.426 -9.362 18.552 1.00 47.81 ? 344 LEU A CA 1 ATOM 2382 C C . LEU A 1 318 ? -50.465 -9.886 20.011 1.00 45.74 ? 344 LEU A C 1 ATOM 2383 O O . LEU A 1 318 ? -49.436 -10.045 20.649 1.00 46.17 ? 344 LEU A O 1 ATOM 2384 C CB . LEU A 1 318 ? -49.366 -8.286 18.397 1.00 46.52 ? 344 LEU A CB 1 ATOM 2385 C CG . LEU A 1 318 ? -48.921 -7.971 16.978 1.00 48.31 ? 344 LEU A CG 1 ATOM 2386 C CD1 . LEU A 1 318 ? -48.203 -6.635 16.922 1.00 51.28 ? 344 LEU A CD1 1 ATOM 2387 C CD2 . LEU A 1 318 ? -48.042 -9.072 16.438 1.00 48.27 ? 344 LEU A CD2 1 ATOM 2388 N N . SER A 1 319 ? -51.659 -10.165 20.506 1.00 39.53 ? 345 SER A N 1 ATOM 2389 C CA . SER A 1 319 ? -51.824 -10.622 21.860 1.00 44.07 ? 345 SER A CA 1 ATOM 2390 C C . SER A 1 319 ? -51.163 -11.942 22.187 1.00 43.80 ? 345 SER A C 1 ATOM 2391 O O . SER A 1 319 ? -50.957 -12.798 21.341 1.00 49.48 ? 345 SER A O 1 ATOM 2392 C CB . SER A 1 319 ? -53.295 -10.734 22.171 1.00 45.06 ? 345 SER A CB 1 ATOM 2393 O OG . SER A 1 319 ? -53.914 -9.465 22.058 1.00 45.36 ? 345 SER A OG 1 ATOM 2394 N N . PHE A 1 320 ? -50.775 -12.062 23.434 1.00 48.93 ? 346 PHE A N 1 ATOM 2395 C CA . PHE A 1 320 ? -50.142 -13.265 23.953 1.00 42.81 ? 346 PHE A CA 1 ATOM 2396 C C . PHE A 1 320 ? -48.971 -13.768 23.177 1.00 45.49 ? 346 PHE A C 1 ATOM 2397 O O . PHE A 1 320 ? -49.027 -14.864 22.602 1.00 43.13 ? 346 PHE A O 1 ATOM 2398 C CB . PHE A 1 320 ? -51.170 -14.367 24.161 1.00 36.88 ? 346 PHE A CB 1 ATOM 2399 C CG . PHE A 1 320 ? -52.259 -13.964 25.110 1.00 41.91 ? 346 PHE A CG 1 ATOM 2400 C CD1 . PHE A 1 320 ? -52.003 -13.865 26.460 1.00 44.98 ? 346 PHE A CD1 1 ATOM 2401 C CD2 . PHE A 1 320 ? -53.516 -13.671 24.656 1.00 42.93 ? 346 PHE A CD2 1 ATOM 2402 C CE1 . PHE A 1 320 ? -52.975 -13.467 27.325 1.00 46.92 ? 346 PHE A CE1 1 ATOM 2403 C CE2 . PHE A 1 320 ? -54.497 -13.256 25.512 1.00 43.33 ? 346 PHE A CE2 1 ATOM 2404 C CZ . PHE A 1 320 ? -54.219 -13.130 26.849 1.00 51.15 ? 346 PHE A CZ 1 ATOM 2405 N N . ASN A 1 321 ? -47.963 -12.907 23.063 1.00 43.29 ? 347 ASN A N 1 ATOM 2406 C CA . ASN A 1 321 ? -46.704 -13.257 22.432 1.00 45.35 ? 347 ASN A CA 1 ATOM 2407 C C . ASN A 1 321 ? -45.613 -13.150 23.485 1.00 43.38 ? 347 ASN A C 1 ATOM 2408 O O . ASN A 1 321 ? -44.434 -13.070 23.165 1.00 48.89 ? 347 ASN A O 1 ATOM 2409 C CB . ASN A 1 321 ? -46.335 -12.374 21.218 1.00 43.20 ? 347 ASN A CB 1 ATOM 2410 C CG . ASN A 1 321 ? -47.028 -12.800 19.946 1.00 45.64 ? 347 ASN A CG 1 ATOM 2411 O OD1 . ASN A 1 321 ? -46.412 -13.471 19.101 1.00 40.28 ? 347 ASN A OD1 1 ATOM 2412 N ND2 . ASN A 1 321 ? -48.337 -12.638 19.907 1.00 48.52 ? 347 ASN A ND2 1 ATOM 2413 N N . TYR A 1 322 ? -45.980 -13.227 24.747 1.00 48.70 ? 348 TYR A N 1 ATOM 2414 C CA . TYR A 1 322 ? -44.965 -13.081 25.803 1.00 47.48 ? 348 TYR A CA 1 ATOM 2415 C C . TYR A 1 322 ? -43.956 -14.178 25.834 1.00 44.56 ? 348 TYR A C 1 ATOM 2416 O O . TYR A 1 322 ? -44.195 -15.262 25.337 1.00 53.88 ? 348 TYR A O 1 ATOM 2417 C CB . TYR A 1 322 ? -45.610 -13.032 27.180 1.00 44.49 ? 348 TYR A CB 1 ATOM 2418 C CG . TYR A 1 322 ? -46.293 -14.314 27.584 1.00 55.63 ? 348 TYR A CG 1 ATOM 2419 C CD1 . TYR A 1 322 ? -47.646 -14.511 27.339 1.00 56.64 ? 348 TYR A CD1 1 ATOM 2420 C CD2 . TYR A 1 322 ? -45.596 -15.313 28.289 1.00 67.54 ? 348 TYR A CD2 1 ATOM 2421 C CE1 . TYR A 1 322 ? -48.287 -15.670 27.736 1.00 69.17 ? 348 TYR A CE1 1 ATOM 2422 C CE2 . TYR A 1 322 ? -46.241 -16.469 28.723 1.00 64.68 ? 348 TYR A CE2 1 ATOM 2423 C CZ . TYR A 1 322 ? -47.578 -16.650 28.427 1.00 72.52 ? 348 TYR A CZ 1 ATOM 2424 O OH . TYR A 1 322 ? -48.219 -17.804 28.799 1.00 73.66 ? 348 TYR A OH 1 ATOM 2425 N N . ILE A 1 323 ? -42.778 -13.839 26.325 1.00 53.85 ? 349 ILE A N 1 ATOM 2426 C CA . ILE A 1 323 ? -41.707 -14.811 26.526 1.00 69.08 ? 349 ILE A CA 1 ATOM 2427 C C . ILE A 1 323 ? -41.861 -15.306 27.989 1.00 59.92 ? 349 ILE A C 1 ATOM 2428 O O . ILE A 1 323 ? -41.775 -14.517 28.906 1.00 54.42 ? 349 ILE A O 1 ATOM 2429 C CB . ILE A 1 323 ? -40.350 -14.151 26.409 1.00 69.62 ? 349 ILE A CB 1 ATOM 2430 C CG1 . ILE A 1 323 ? -40.203 -13.558 25.007 1.00 65.77 ? 349 ILE A CG1 1 ATOM 2431 C CG2 . ILE A 1 323 ? -39.274 -15.173 26.720 1.00 64.58 ? 349 ILE A CG2 1 ATOM 2432 C CD1 . ILE A 1 323 ? -38.988 -12.671 24.836 1.00 60.15 ? 349 ILE A CD1 1 ATOM 2433 N N . LYS A 1 324 ? -42.085 -16.598 28.180 1.00 63.95 ? 350 LYS A N 1 ATOM 2434 C CA . LYS A 1 324 ? -42.284 -17.189 29.531 1.00 77.98 ? 350 LYS A CA 1 ATOM 2435 C C . LYS A 1 324 ? -41.231 -16.726 30.491 1.00 60.89 ? 350 LYS A C 1 ATOM 2436 O O . LYS A 1 324 ? -40.040 -16.754 30.199 1.00 59.49 ? 350 LYS A O 1 ATOM 2437 C CB . LYS A 1 324 ? -42.201 -18.722 29.516 1.00 83.75 ? 350 LYS A CB 1 ATOM 2438 C CG . LYS A 1 324 ? -42.638 -19.284 28.193 1.00 109.87 ? 350 LYS A CG 1 ATOM 2439 C CD . LYS A 1 324 ? -41.496 -19.048 27.200 1.00 120.15 ? 350 LYS A CD 1 ATOM 2440 C CE . LYS A 1 324 ? -41.906 -19.021 25.739 1.00 111.57 ? 350 LYS A CE 1 ATOM 2441 N NZ . LYS A 1 324 ? -40.703 -18.777 24.888 1.00 104.11 ? 350 LYS A NZ 1 ATOM 2442 N N . GLY A 1 325 ? -41.679 -16.244 31.623 1.00 58.20 ? 351 GLY A N 1 ATOM 2443 C CA . GLY A 1 325 ? -40.768 -15.811 32.653 1.00 61.86 ? 351 GLY A CA 1 ATOM 2444 C C . GLY A 1 325 ? -40.103 -14.489 32.440 1.00 64.91 ? 351 GLY A C 1 ATOM 2445 O O . GLY A 1 325 ? -39.408 -14.014 33.330 1.00 73.30 ? 351 GLY A O 1 ATOM 2446 N N . SER A 1 326 ? -40.357 -13.845 31.306 1.00 67.85 ? 352 SER A N 1 ATOM 2447 C CA . SER A 1 326 ? -39.747 -12.545 31.054 1.00 61.02 ? 352 SER A CA 1 ATOM 2448 C C . SER A 1 326 ? -40.699 -11.437 31.474 1.00 61.36 ? 352 SER A C 1 ATOM 2449 O O . SER A 1 326 ? -41.903 -11.552 31.269 1.00 69.28 ? 352 SER A O 1 ATOM 2450 C CB . SER A 1 326 ? -39.382 -12.393 29.599 1.00 64.34 ? 352 SER A CB 1 ATOM 2451 O OG . SER A 1 326 ? -38.646 -11.196 29.419 1.00 76.44 ? 352 SER A OG 1 ATOM 2452 N N . TYR A 1 327 ? -40.171 -10.399 32.121 1.00 59.15 ? 353 TYR A N 1 ATOM 2453 C CA . TYR A 1 327 ? -41.000 -9.281 32.567 1.00 54.30 ? 353 TYR A CA 1 ATOM 2454 C C . TYR A 1 327 ? -40.241 -7.971 32.394 1.00 49.18 ? 353 TYR A C 1 ATOM 2455 O O . TYR A 1 327 ? -39.945 -7.258 33.349 1.00 51.60 ? 353 TYR A O 1 ATOM 2456 C CB . TYR A 1 327 ? -41.455 -9.544 33.990 1.00 55.18 ? 353 TYR A CB 1 ATOM 2457 C CG . TYR A 1 327 ? -42.406 -8.558 34.613 1.00 55.90 ? 353 TYR A CG 1 ATOM 2458 C CD1 . TYR A 1 327 ? -43.518 -8.116 33.913 1.00 61.21 ? 353 TYR A CD1 1 ATOM 2459 C CD2 . TYR A 1 327 ? -42.455 -8.443 35.999 1.00 52.31 ? 353 TYR A CD2 1 ATOM 2460 C CE1 . TYR A 1 327 ? -44.492 -7.327 34.526 1.00 56.34 ? 353 TYR A CE1 1 ATOM 2461 C CE2 . TYR A 1 327 ? -43.438 -7.696 36.628 1.00 57.23 ? 353 TYR A CE2 1 ATOM 2462 C CZ . TYR A 1 327 ? -44.451 -7.133 35.881 1.00 57.00 ? 353 TYR A CZ 1 ATOM 2463 O OH . TYR A 1 327 ? -45.452 -6.442 36.504 1.00 56.32 ? 353 TYR A OH 1 ATOM 2464 N N . PRO A 1 328 ? -39.936 -7.647 31.138 1.00 51.70 ? 354 PRO A N 1 ATOM 2465 C CA . PRO A 1 328 ? -39.199 -6.436 30.767 1.00 47.05 ? 354 PRO A CA 1 ATOM 2466 C C . PRO A 1 328 ? -39.769 -5.179 31.349 1.00 47.44 ? 354 PRO A C 1 ATOM 2467 O O . PRO A 1 328 ? -40.971 -5.101 31.645 1.00 53.61 ? 354 PRO A O 1 ATOM 2468 C CB . PRO A 1 328 ? -39.323 -6.401 29.230 1.00 43.88 ? 354 PRO A CB 1 ATOM 2469 C CG . PRO A 1 328 ? -40.455 -7.316 28.904 1.00 52.32 ? 354 PRO A CG 1 ATOM 2470 C CD . PRO A 1 328 ? -40.405 -8.384 29.953 1.00 50.01 ? 354 PRO A CD 1 ATOM 2471 N N . GLN A 1 329 ? -38.901 -4.206 31.566 1.00 54.43 ? 355 GLN A N 1 ATOM 2472 C CA . GLN A 1 329 ? -39.339 -2.942 32.098 1.00 54.98 ? 355 GLN A CA 1 ATOM 2473 C C . GLN A 1 329 ? -40.250 -2.197 31.162 1.00 54.79 ? 355 GLN A C 1 ATOM 2474 O O . GLN A 1 329 ? -41.181 -1.531 31.614 1.00 57.13 ? 355 GLN A O 1 ATOM 2475 C CB . GLN A 1 329 ? -38.176 -2.026 32.431 1.00 63.81 ? 355 GLN A CB 1 ATOM 2476 C CG . GLN A 1 329 ? -37.453 -2.332 33.716 1.00 86.16 ? 355 GLN A CG 1 ATOM 2477 C CD . GLN A 1 329 ? -36.529 -1.187 34.096 1.00 109.67 ? 355 GLN A CD 1 ATOM 2478 O OE1 . GLN A 1 329 ? -35.976 -0.499 33.232 1.00 100.77 ? 355 GLN A OE1 1 ATOM 2479 N NE2 . GLN A 1 329 ? -36.380 -0.961 35.390 1.00 126.84 ? 355 GLN A NE2 1 ATOM 2480 N N . HIS A 1 330 ? -39.963 -2.272 29.865 1.00 55.04 ? 356 HIS A N 1 ATOM 2481 C CA . HIS A 1 330 ? -40.766 -1.556 28.880 1.00 67.67 ? 356 HIS A CA 1 ATOM 2482 C C . HIS A 1 330 ? -41.184 -2.422 27.718 1.00 60.63 ? 356 HIS A C 1 ATOM 2483 O O . HIS A 1 330 ? -40.593 -3.463 27.455 1.00 63.39 ? 356 HIS A O 1 ATOM 2484 C CB . HIS A 1 330 ? -39.954 -0.378 28.296 1.00 66.97 ? 356 HIS A CB 1 ATOM 2485 C CG . HIS A 1 330 ? -39.414 0.548 29.325 1.00 65.60 ? 356 HIS A CG 1 ATOM 2486 N ND1 . HIS A 1 330 ? -38.105 0.494 29.749 1.00 68.98 ? 356 HIS A ND1 1 ATOM 2487 C CD2 . HIS A 1 330 ? -40.029 1.464 30.109 1.00 76.29 ? 356 HIS A CD2 1 ATOM 2488 C CE1 . HIS A 1 330 ? -37.925 1.370 30.723 1.00 74.01 ? 356 HIS A CE1 1 ATOM 2489 N NE2 . HIS A 1 330 ? -39.078 1.969 30.965 1.00 77.17 ? 356 HIS A NE2 1 ATOM 2490 N N . ILE A 1 331 ? -42.199 -1.966 26.999 1.00 62.60 ? 357 ILE A N 1 ATOM 2491 C CA . ILE A 1 331 ? -42.650 -2.681 25.810 1.00 56.74 ? 357 ILE A CA 1 ATOM 2492 C C . ILE A 1 331 ? -41.785 -2.091 24.691 1.00 53.95 ? 357 ILE A C 1 ATOM 2493 O O . ILE A 1 331 ? -41.560 -0.885 24.673 1.00 51.29 ? 357 ILE A O 1 ATOM 2494 C CB . ILE A 1 331 ? -44.157 -2.488 25.547 1.00 52.18 ? 357 ILE A CB 1 ATOM 2495 C CG1 . ILE A 1 331 ? -44.558 -3.240 24.294 1.00 50.60 ? 357 ILE A CG1 1 ATOM 2496 C CG2 . ILE A 1 331 ? -44.519 -1.020 25.400 1.00 54.44 ? 357 ILE A CG2 1 ATOM 2497 C CD1 . ILE A 1 331 ? -46.044 -3.234 24.069 1.00 51.21 ? 357 ILE A CD1 1 ATOM 2498 N N . ASN A 1 332 ? -41.220 -2.940 23.835 1.00 52.23 ? 358 ASN A N 1 ATOM 2499 C CA . ASN A 1 332 ? -40.364 -2.468 22.750 1.00 52.37 ? 358 ASN A CA 1 ATOM 2500 C C . ASN A 1 332 ? -41.110 -2.512 21.406 1.00 54.12 ? 358 ASN A C 1 ATOM 2501 O O . ASN A 1 332 ? -41.161 -3.540 20.706 1.00 55.12 ? 358 ASN A O 1 ATOM 2502 C CB . ASN A 1 332 ? -39.069 -3.281 22.700 1.00 54.12 ? 358 ASN A CB 1 ATOM 2503 C CG . ASN A 1 332 ? -38.006 -2.614 21.873 1.00 59.59 ? 358 ASN A CG 1 ATOM 2504 O OD1 . ASN A 1 332 ? -38.220 -1.531 21.369 1.00 63.52 ? 358 ASN A OD1 1 ATOM 2505 N ND2 . ASN A 1 332 ? -36.829 -3.211 21.806 1.00 69.46 ? 358 ASN A ND2 1 ATOM 2506 N N . ILE A 1 333 ? -41.692 -1.371 21.074 1.00 47.99 ? 359 ILE A N 1 ATOM 2507 C CA . ILE A 1 333 ? -42.496 -1.179 19.855 1.00 50.75 ? 359 ILE A CA 1 ATOM 2508 C C . ILE A 1 333 ? -41.685 -0.535 18.733 1.00 49.21 ? 359 ILE A C 1 ATOM 2509 O O . ILE A 1 333 ? -41.269 0.631 18.839 1.00 51.29 ? 359 ILE A O 1 ATOM 2510 C CB . ILE A 1 333 ? -43.689 -0.236 20.203 1.00 55.68 ? 359 ILE A CB 1 ATOM 2511 C CG1 . ILE A 1 333 ? -44.602 -0.880 21.241 1.00 56.42 ? 359 ILE A CG1 1 ATOM 2512 C CG2 . ILE A 1 333 ? -44.515 0.134 18.988 1.00 58.29 ? 359 ILE A CG2 1 ATOM 2513 C CD1 . ILE A 1 333 ? -45.228 -2.158 20.762 1.00 61.02 ? 359 ILE A CD1 1 ATOM 2514 N N . SER A 1 334 ? -41.452 -1.270 17.663 1.00 51.04 ? 360 SER A N 1 ATOM 2515 C CA . SER A 1 334 ? -40.698 -0.734 16.504 1.00 54.84 ? 360 SER A CA 1 ATOM 2516 C C . SER A 1 334 ? -41.137 0.634 15.955 1.00 55.13 ? 360 SER A C 1 ATOM 2517 O O . SER A 1 334 ? -42.304 1.008 16.062 1.00 49.96 ? 360 SER A O 1 ATOM 2518 C CB . SER A 1 334 ? -40.858 -1.681 15.346 1.00 56.29 ? 360 SER A CB 1 ATOM 2519 O OG . SER A 1 334 ? -40.230 -1.151 14.213 1.00 50.61 ? 360 SER A OG 1 ATOM 2520 N N . ARG A 1 335 ? -40.199 1.352 15.321 1.00 64.05 ? 361 ARG A N 1 ATOM 2521 C CA . ARG A 1 335 ? -40.509 2.660 14.676 1.00 61.32 ? 361 ARG A CA 1 ATOM 2522 C C . ARG A 1 335 ? -41.479 2.431 13.515 1.00 52.11 ? 361 ARG A C 1 ATOM 2523 O O . ARG A 1 335 ? -42.366 3.229 13.270 1.00 53.16 ? 361 ARG A O 1 ATOM 2524 C CB . ARG A 1 335 ? -39.264 3.354 14.130 1.00 60.98 ? 361 ARG A CB 1 ATOM 2525 C CG . ARG A 1 335 ? -38.373 3.979 15.179 1.00 91.65 ? 361 ARG A CG 1 ATOM 2526 C CD . ARG A 1 335 ? -37.177 4.697 14.552 1.00 113.28 ? 361 ARG A CD 1 ATOM 2527 N NE . ARG A 1 335 ? -36.441 5.476 15.553 1.00 121.24 ? 361 ARG A NE 1 ATOM 2528 C CZ . ARG A 1 335 ? -36.712 6.745 15.866 1.00 126.11 ? 361 ARG A CZ 1 ATOM 2529 N NH1 . ARG A 1 335 ? -37.689 7.408 15.246 1.00 119.41 ? 361 ARG A NH1 1 ATOM 2530 N NH2 . ARG A 1 335 ? -36.000 7.362 16.798 1.00 129.48 ? 361 ARG A NH2 1 ATOM 2531 N N . ASN A 1 336 ? -41.351 1.285 12.872 1.00 48.03 ? 362 ASN A N 1 ATOM 2532 C CA . ASN A 1 336 ? -42.207 0.922 11.752 1.00 52.46 ? 362 ASN A CA 1 ATOM 2533 C C . ASN A 1 336 ? -43.694 0.865 12.059 1.00 55.73 ? 362 ASN A C 1 ATOM 2534 O O . ASN A 1 336 ? -44.510 0.828 11.132 1.00 59.35 ? 362 ASN A O 1 ATOM 2535 C CB . ASN A 1 336 ? -41.669 -0.333 11.093 1.00 57.36 ? 362 ASN A CB 1 ATOM 2536 C CG . ASN A 1 336 ? -40.260 -0.116 10.558 1.00 62.44 ? 362 ASN A CG 1 ATOM 2537 O OD1 . ASN A 1 336 ? -39.866 1.017 10.313 1.00 63.67 ? 362 ASN A OD1 1 ATOM 2538 N ND2 . ASN A 1 336 ? -39.499 -1.180 10.400 1.00 68.27 ? 362 ASN A ND2 1 ATOM 2539 N N . PHE A 1 337 ? -44.075 0.857 13.342 1.00 56.31 ? 363 PHE A N 1 ATOM 2540 C CA . PHE A 1 337 ? -45.513 0.891 13.658 1.00 52.03 ? 363 PHE A CA 1 ATOM 2541 C C . PHE A 1 337 ? -46.115 2.149 13.042 1.00 53.05 ? 363 PHE A C 1 ATOM 2542 O O . PHE A 1 337 ? -47.274 2.139 12.638 1.00 50.82 ? 363 PHE A O 1 ATOM 2543 C CB . PHE A 1 337 ? -45.826 0.800 15.192 1.00 49.52 ? 363 PHE A CB 1 ATOM 2544 C CG . PHE A 1 337 ? -46.059 -0.606 15.680 1.00 48.98 ? 363 PHE A CG 1 ATOM 2545 C CD1 . PHE A 1 337 ? -45.005 -1.482 15.895 1.00 50.56 ? 363 PHE A CD1 1 ATOM 2546 C CD2 . PHE A 1 337 ? -47.343 -1.080 15.802 1.00 51.62 ? 363 PHE A CD2 1 ATOM 2547 C CE1 . PHE A 1 337 ? -45.226 -2.804 16.211 1.00 49.13 ? 363 PHE A CE1 1 ATOM 2548 C CE2 . PHE A 1 337 ? -47.571 -2.405 16.115 1.00 59.36 ? 363 PHE A CE2 1 ATOM 2549 C CZ . PHE A 1 337 ? -46.503 -3.266 16.334 1.00 52.81 ? 363 PHE A CZ 1 ATOM 2550 N N . SER A 1 338 ? -45.313 3.225 12.984 1.00 59.71 ? 364 SER A N 1 ATOM 2551 C CA . SER A 1 338 ? -45.740 4.551 12.429 1.00 57.70 ? 364 SER A CA 1 ATOM 2552 C C . SER A 1 338 ? -46.212 4.415 10.988 1.00 46.14 ? 364 SER A C 1 ATOM 2553 O O . SER A 1 338 ? -46.991 5.220 10.517 1.00 53.51 ? 364 SER A O 1 ATOM 2554 C CB . SER A 1 338 ? -44.606 5.576 12.459 1.00 45.66 ? 364 SER A CB 1 ATOM 2555 O OG . SER A 1 338 ? -43.658 5.202 11.501 1.00 46.83 ? 364 SER A OG 1 ATOM 2556 N N . LYS A 1 339 ? -45.748 3.388 10.305 1.00 40.41 ? 365 LYS A N 1 ATOM 2557 C CA . LYS A 1 339 ? -46.187 3.123 8.943 1.00 39.45 ? 365 LYS A CA 1 ATOM 2558 C C . LYS A 1 339 ? -47.540 2.417 8.752 1.00 47.30 ? 365 LYS A C 1 ATOM 2559 O O . LYS A 1 339 ? -47.924 2.186 7.616 1.00 53.47 ? 365 LYS A O 1 ATOM 2560 C CB . LYS A 1 339 ? -45.119 2.348 8.189 1.00 41.29 ? 365 LYS A CB 1 ATOM 2561 C CG . LYS A 1 339 ? -43.843 3.158 8.105 1.00 47.84 ? 365 LYS A CG 1 ATOM 2562 C CD . LYS A 1 339 ? -42.832 2.554 7.179 1.00 65.21 ? 365 LYS A CD 1 ATOM 2563 C CE . LYS A 1 339 ? -41.561 3.385 7.222 1.00 83.17 ? 365 LYS A CE 1 ATOM 2564 N NZ . LYS A 1 339 ? -41.869 4.810 6.932 1.00 86.08 ? 365 LYS A NZ 1 ATOM 2565 N N . LEU A 1 340 ? -48.258 2.055 9.824 1.00 52.60 ? 366 LEU A N 1 ATOM 2566 C CA . LEU A 1 340 ? -49.581 1.372 9.683 1.00 50.65 ? 366 LEU A CA 1 ATOM 2567 C C . LEU A 1 340 ? -50.619 2.478 9.665 1.00 53.13 ? 366 LEU A C 1 ATOM 2568 O O . LEU A 1 340 ? -51.448 2.613 10.579 1.00 50.69 ? 366 LEU A O 1 ATOM 2569 C CB . LEU A 1 340 ? -49.833 0.428 10.869 1.00 51.91 ? 366 LEU A CB 1 ATOM 2570 C CG . LEU A 1 340 ? -48.814 -0.703 11.083 1.00 48.90 ? 366 LEU A CG 1 ATOM 2571 C CD1 . LEU A 1 340 ? -48.986 -1.323 12.445 1.00 50.64 ? 366 LEU A CD1 1 ATOM 2572 C CD2 . LEU A 1 340 ? -48.832 -1.756 10.008 1.00 44.44 ? 366 LEU A CD2 1 ATOM 2573 N N . LEU A 1 341 ? -50.653 3.188 8.552 1.00 54.31 ? 367 LEU A N 1 ATOM 2574 C CA . LEU A 1 341 ? -51.523 4.347 8.430 1.00 48.08 ? 367 LEU A CA 1 ATOM 2575 C C . LEU A 1 341 ? -52.992 4.120 8.433 1.00 48.11 ? 367 LEU A C 1 ATOM 2576 O O . LEU A 1 341 ? -53.733 5.054 8.693 1.00 48.57 ? 367 LEU A O 1 ATOM 2577 C CB . LEU A 1 341 ? -51.122 5.170 7.224 1.00 47.82 ? 367 LEU A CB 1 ATOM 2578 C CG . LEU A 1 341 ? -49.706 5.750 7.222 1.00 48.67 ? 367 LEU A CG 1 ATOM 2579 C CD1 . LEU A 1 341 ? -49.473 6.533 5.937 1.00 53.64 ? 367 LEU A CD1 1 ATOM 2580 C CD2 . LEU A 1 341 ? -49.493 6.668 8.411 1.00 50.36 ? 367 LEU A CD2 1 ATOM 2581 N N . SER A 1 342 ? -53.447 2.902 8.176 1.00 45.28 ? 368 SER A N 1 ATOM 2582 C CA . SER A 1 342 ? -54.887 2.663 8.183 1.00 46.09 ? 368 SER A CA 1 ATOM 2583 C C . SER A 1 342 ? -55.333 1.936 9.486 1.00 49.24 ? 368 SER A C 1 ATOM 2584 O O . SER A 1 342 ? -56.531 1.685 9.690 1.00 43.68 ? 368 SER A O 1 ATOM 2585 C CB . SER A 1 342 ? -55.262 1.821 6.974 1.00 52.36 ? 368 SER A CB 1 ATOM 2586 O OG . SER A 1 342 ? -54.751 2.366 5.779 1.00 44.94 ? 368 SER A OG 1 ATOM 2587 N N . LEU A 1 343 ? -54.396 1.731 10.409 1.00 42.77 ? 369 LEU A N 1 ATOM 2588 C CA . LEU A 1 343 ? -54.680 1.006 11.664 1.00 47.47 ? 369 LEU A CA 1 ATOM 2589 C C . LEU A 1 343 ? -55.758 1.616 12.515 1.00 41.70 ? 369 LEU A C 1 ATOM 2590 O O . LEU A 1 343 ? -55.678 2.766 12.898 1.00 46.42 ? 369 LEU A O 1 ATOM 2591 C CB . LEU A 1 343 ? -53.412 0.907 12.531 1.00 49.46 ? 369 LEU A CB 1 ATOM 2592 C CG . LEU A 1 343 ? -53.444 -0.207 13.591 1.00 48.74 ? 369 LEU A CG 1 ATOM 2593 C CD1 . LEU A 1 343 ? -53.463 -1.570 12.894 1.00 43.34 ? 369 LEU A CD1 1 ATOM 2594 C CD2 . LEU A 1 343 ? -52.220 -0.157 14.500 1.00 45.60 ? 369 LEU A CD2 1 ATOM 2595 N N . ARG A 1 344 ? -56.780 0.834 12.810 1.00 47.94 ? 370 ARG A N 1 ATOM 2596 C CA . ARG A 1 344 ? -57.864 1.294 13.646 1.00 49.65 ? 370 ARG A CA 1 ATOM 2597 C C . ARG A 1 344 ? -57.820 0.640 15.045 1.00 51.24 ? 370 ARG A C 1 ATOM 2598 O O . ARG A 1 344 ? -58.327 1.210 16.019 1.00 49.51 ? 370 ARG A O 1 ATOM 2599 C CB . ARG A 1 344 ? -59.199 0.942 13.041 1.00 56.91 ? 370 ARG A CB 1 ATOM 2600 C CG . ARG A 1 344 ? -59.459 1.416 11.630 1.00 59.50 ? 370 ARG A CG 1 ATOM 2601 C CD . ARG A 1 344 ? -60.925 1.141 11.336 1.00 63.56 ? 370 ARG A CD 1 ATOM 2602 N NE . ARG A 1 344 ? -61.280 1.273 9.929 1.00 90.23 ? 370 ARG A NE 1 ATOM 2603 C CZ . ARG A 1 344 ? -62.507 1.048 9.455 1.00 107.16 ? 370 ARG A CZ 1 ATOM 2604 N NH1 . ARG A 1 344 ? -63.498 0.739 10.296 1.00 103.06 ? 370 ARG A NH1 1 ATOM 2605 N NH2 . ARG A 1 344 ? -62.759 1.166 8.150 1.00 99.07 ? 370 ARG A NH2 1 ATOM 2606 N N . ALA A 1 345 ? -57.283 -0.580 15.127 1.00 46.70 ? 371 ALA A N 1 ATOM 2607 C CA . ALA A 1 345 ? -57.196 -1.303 16.407 1.00 42.10 ? 371 ALA A CA 1 ATOM 2608 C C . ALA A 1 345 ? -55.958 -2.116 16.506 1.00 40.80 ? 371 ALA A C 1 ATOM 2609 O O . ALA A 1 345 ? -55.636 -2.890 15.606 1.00 42.22 ? 371 ALA A O 1 ATOM 2610 C CB . ALA A 1 345 ? -58.376 -2.202 16.598 1.00 41.04 ? 371 ALA A CB 1 ATOM 2611 N N . LEU A 1 346 ? -55.291 -1.962 17.641 1.00 37.73 ? 372 LEU A N 1 ATOM 2612 C CA . LEU A 1 346 ? -54.081 -2.666 17.940 1.00 42.91 ? 372 LEU A CA 1 ATOM 2613 C C . LEU A 1 346 ? -54.328 -3.500 19.223 1.00 49.16 ? 372 LEU A C 1 ATOM 2614 O O . LEU A 1 346 ? -54.682 -2.961 20.303 1.00 37.32 ? 372 LEU A O 1 ATOM 2615 C CB . LEU A 1 346 ? -52.990 -1.661 18.210 1.00 43.22 ? 372 LEU A CB 1 ATOM 2616 C CG . LEU A 1 346 ? -51.633 -2.221 18.570 1.00 47.44 ? 372 LEU A CG 1 ATOM 2617 C CD1 . LEU A 1 346 ? -51.083 -3.115 17.462 1.00 47.28 ? 372 LEU A CD1 1 ATOM 2618 C CD2 . LEU A 1 346 ? -50.694 -1.055 18.800 1.00 46.25 ? 372 LEU A CD2 1 ATOM 2619 N N . HIS A 1 347 ? -54.208 -4.811 19.091 1.00 47.96 ? 373 HIS A N 1 ATOM 2620 C CA . HIS A 1 347 ? -54.415 -5.707 20.234 1.00 43.16 ? 373 HIS A CA 1 ATOM 2621 C C . HIS A 1 347 ? -53.094 -6.251 20.693 1.00 39.86 ? 373 HIS A C 1 ATOM 2622 O O . HIS A 1 347 ? -52.443 -7.037 19.975 1.00 41.10 ? 373 HIS A O 1 ATOM 2623 C CB . HIS A 1 347 ? -55.384 -6.815 19.887 1.00 41.62 ? 373 HIS A CB 1 ATOM 2624 C CG . HIS A 1 347 ? -56.751 -6.319 19.559 1.00 42.72 ? 373 HIS A CG 1 ATOM 2625 N ND1 . HIS A 1 347 ? -57.644 -5.935 20.525 1.00 45.70 ? 373 HIS A ND1 1 ATOM 2626 C CD2 . HIS A 1 347 ? -57.390 -6.166 18.375 1.00 46.69 ? 373 HIS A CD2 1 ATOM 2627 C CE1 . HIS A 1 347 ? -58.771 -5.541 19.955 1.00 48.88 ? 373 HIS A CE1 1 ATOM 2628 N NE2 . HIS A 1 347 ? -58.632 -5.645 18.647 1.00 45.80 ? 373 HIS A NE2 1 ATOM 2629 N N . LEU A 1 348 ? -52.680 -5.755 21.862 1.00 41.09 ? 374 LEU A N 1 ATOM 2630 C CA . LEU A 1 348 ? -51.418 -6.104 22.515 1.00 48.48 ? 374 LEU A CA 1 ATOM 2631 C C . LEU A 1 348 ? -51.594 -6.684 23.901 1.00 48.55 ? 374 LEU A C 1 ATOM 2632 O O . LEU A 1 348 ? -50.912 -6.280 24.850 1.00 44.31 ? 374 LEU A O 1 ATOM 2633 C CB . LEU A 1 348 ? -50.492 -4.887 22.611 1.00 49.12 ? 374 LEU A CB 1 ATOM 2634 C CG . LEU A 1 348 ? -49.707 -4.564 21.363 1.00 52.74 ? 374 LEU A CG 1 ATOM 2635 C CD1 . LEU A 1 348 ? -49.045 -3.203 21.425 1.00 56.52 ? 374 LEU A CD1 1 ATOM 2636 C CD2 . LEU A 1 348 ? -48.681 -5.657 21.199 1.00 57.11 ? 374 LEU A CD2 1 ATOM 2637 N N . ARG A 1 349 ? -52.535 -7.593 24.048 1.00 45.52 ? 375 ARG A N 1 ATOM 2638 C CA . ARG A 1 349 ? -52.678 -8.198 25.338 1.00 50.14 ? 375 ARG A CA 1 ATOM 2639 C C . ARG A 1 349 ? -51.578 -9.195 25.587 1.00 52.57 ? 375 ARG A C 1 ATOM 2640 O O . ARG A 1 349 ? -50.930 -9.702 24.653 1.00 45.49 ? 375 ARG A O 1 ATOM 2641 C CB . ARG A 1 349 ? -53.994 -8.915 25.507 1.00 44.63 ? 375 ARG A CB 1 ATOM 2642 C CG . ARG A 1 349 ? -55.126 -7.945 25.507 1.00 55.79 ? 375 ARG A CG 1 ATOM 2643 C CD . ARG A 1 349 ? -56.367 -8.556 26.075 1.00 58.39 ? 375 ARG A CD 1 ATOM 2644 N NE . ARG A 1 349 ? -56.655 -9.787 25.420 1.00 73.66 ? 375 ARG A NE 1 ATOM 2645 C CZ . ARG A 1 349 ? -57.691 -10.539 25.715 1.00 100.69 ? 375 ARG A CZ 1 ATOM 2646 N NH1 . ARG A 1 349 ? -58.566 -10.128 26.630 1.00 88.77 ? 375 ARG A NH1 1 ATOM 2647 N NH2 . ARG A 1 349 ? -57.861 -11.677 25.058 1.00 122.76 ? 375 ARG A NH2 1 ATOM 2648 N N . GLY A 1 350 ? -51.239 -9.338 26.852 1.00 44.99 ? 376 GLY A N 1 ATOM 2649 C CA . GLY A 1 350 ? -50.270 -10.344 27.215 1.00 46.56 ? 376 GLY A CA 1 ATOM 2650 C C . GLY A 1 350 ? -48.915 -10.350 26.598 1.00 43.98 ? 376 GLY A C 1 ATOM 2651 O O . GLY A 1 350 ? -48.445 -11.390 26.125 1.00 41.21 ? 376 GLY A O 1 ATOM 2652 N N . TYR A 1 351 ? -48.317 -9.177 26.546 1.00 46.28 ? 377 TYR A N 1 ATOM 2653 C CA . TYR A 1 351 ? -46.951 -9.035 26.070 1.00 50.36 ? 377 TYR A CA 1 ATOM 2654 C C . TYR A 1 351 ? -46.170 -9.169 27.390 1.00 43.77 ? 377 TYR A C 1 ATOM 2655 O O . TYR A 1 351 ? -45.128 -9.746 27.464 1.00 47.35 ? 377 TYR A O 1 ATOM 2656 C CB . TYR A 1 351 ? -46.749 -7.651 25.458 1.00 44.49 ? 377 TYR A CB 1 ATOM 2657 C CG . TYR A 1 351 ? -45.333 -7.338 25.067 1.00 46.18 ? 377 TYR A CG 1 ATOM 2658 C CD1 . TYR A 1 351 ? -44.451 -6.829 25.996 1.00 54.98 ? 377 TYR A CD1 1 ATOM 2659 C CD2 . TYR A 1 351 ? -44.922 -7.408 23.753 1.00 50.24 ? 377 TYR A CD2 1 ATOM 2660 C CE1 . TYR A 1 351 ? -43.178 -6.458 25.651 1.00 50.34 ? 377 TYR A CE1 1 ATOM 2661 C CE2 . TYR A 1 351 ? -43.638 -7.062 23.393 1.00 52.49 ? 377 TYR A CE2 1 ATOM 2662 C CZ . TYR A 1 351 ? -42.774 -6.558 24.345 1.00 55.89 ? 377 TYR A CZ 1 ATOM 2663 O OH . TYR A 1 351 ? -41.477 -6.178 24.002 1.00 53.93 ? 377 TYR A OH 1 ATOM 2664 N N . VAL A 1 352 ? -46.693 -8.521 28.408 1.00 43.22 ? 378 VAL A N 1 ATOM 2665 C CA . VAL A 1 352 ? -46.151 -8.565 29.754 1.00 47.24 ? 378 VAL A CA 1 ATOM 2666 C C . VAL A 1 352 ? -44.931 -7.692 29.930 1.00 44.63 ? 378 VAL A C 1 ATOM 2667 O O . VAL A 1 352 ? -43.826 -8.053 29.539 1.00 48.48 ? 378 VAL A O 1 ATOM 2668 C CB . VAL A 1 352 ? -45.877 -10.006 30.220 1.00 49.09 ? 378 VAL A CB 1 ATOM 2669 C CG1 . VAL A 1 352 ? -45.649 -9.990 31.727 1.00 49.20 ? 378 VAL A CG1 1 ATOM 2670 C CG2 . VAL A 1 352 ? -47.081 -10.908 29.920 1.00 43.41 ? 378 VAL A CG2 1 ATOM 2671 N N . PHE A 1 353 ? -45.136 -6.564 30.606 1.00 40.10 ? 379 PHE A N 1 ATOM 2672 C CA . PHE A 1 353 ? -44.068 -5.605 30.822 1.00 40.90 ? 379 PHE A CA 1 ATOM 2673 C C . PHE A 1 353 ? -44.479 -4.777 32.001 1.00 42.20 ? 379 PHE A C 1 ATOM 2674 O O . PHE A 1 353 ? -45.665 -4.716 32.293 1.00 49.36 ? 379 PHE A O 1 ATOM 2675 C CB . PHE A 1 353 ? -43.812 -4.772 29.566 1.00 44.20 ? 379 PHE A CB 1 ATOM 2676 C CG . PHE A 1 353 ? -44.981 -3.954 29.101 1.00 40.18 ? 379 PHE A CG 1 ATOM 2677 C CD1 . PHE A 1 353 ? -45.961 -4.510 28.306 1.00 46.64 ? 379 PHE A CD1 1 ATOM 2678 C CD2 . PHE A 1 353 ? -44.993 -2.589 29.297 1.00 44.79 ? 379 PHE A CD2 1 ATOM 2679 C CE1 . PHE A 1 353 ? -47.010 -3.735 27.821 1.00 44.85 ? 379 PHE A CE1 1 ATOM 2680 C CE2 . PHE A 1 353 ? -46.024 -1.806 28.805 1.00 41.49 ? 379 PHE A CE2 1 ATOM 2681 C CZ . PHE A 1 353 ? -47.032 -2.389 28.065 1.00 43.04 ? 379 PHE A CZ 1 ATOM 2682 N N . GLN A 1 354 ? -43.567 -3.987 32.554 1.00 47.36 ? 380 GLN A N 1 ATOM 2683 C CA . GLN A 1 354 ? -43.887 -3.260 33.806 1.00 52.68 ? 380 GLN A CA 1 ATOM 2684 C C . GLN A 1 354 ? -44.279 -1.830 33.745 1.00 58.74 ? 380 GLN A C 1 ATOM 2685 O O . GLN A 1 354 ? -45.057 -1.339 34.586 1.00 51.88 ? 380 GLN A O 1 ATOM 2686 C CB . GLN A 1 354 ? -42.660 -3.333 34.712 1.00 54.60 ? 380 GLN A CB 1 ATOM 2687 C CG . GLN A 1 354 ? -42.133 -4.760 34.886 1.00 62.28 ? 380 GLN A CG 1 ATOM 2688 C CD . GLN A 1 354 ? -40.850 -4.835 35.695 1.00 56.15 ? 380 GLN A CD 1 ATOM 2689 O OE1 . GLN A 1 354 ? -40.688 -4.162 36.698 1.00 56.43 ? 380 GLN A OE1 1 ATOM 2690 N NE2 . GLN A 1 354 ? -39.981 -5.724 35.303 1.00 61.09 ? 380 GLN A NE2 1 ATOM 2691 N N . GLU A 1 355 ? -43.721 -1.137 32.774 1.00 60.82 ? 381 GLU A N 1 ATOM 2692 C CA . GLU A 1 355 ? -43.976 0.254 32.669 1.00 62.39 ? 381 GLU A CA 1 ATOM 2693 C C . GLU A 1 355 ? -44.240 0.721 31.235 1.00 56.68 ? 381 GLU A C 1 ATOM 2694 O O . GLU A 1 355 ? -43.695 0.175 30.273 1.00 59.49 ? 381 GLU A O 1 ATOM 2695 C CB . GLU A 1 355 ? -42.759 0.949 33.268 1.00 70.01 ? 381 GLU A CB 1 ATOM 2696 C CG . GLU A 1 355 ? -42.853 2.457 33.365 1.00 102.57 ? 381 GLU A CG 1 ATOM 2697 C CD . GLU A 1 355 ? -41.624 3.065 34.007 1.00 105.98 ? 381 GLU A CD 1 ATOM 2698 O OE1 . GLU A 1 355 ? -40.721 2.288 34.405 1.00 94.31 ? 381 GLU A OE1 1 ATOM 2699 O OE2 . GLU A 1 355 ? -41.579 4.311 34.119 1.00 111.45 ? 381 GLU A OE2 1 ATOM 2700 N N . LEU A 1 356 ? -45.152 1.681 31.096 1.00 57.42 ? 382 LEU A N 1 ATOM 2701 C CA . LEU A 1 356 ? -45.466 2.244 29.779 1.00 59.32 ? 382 LEU A CA 1 ATOM 2702 C C . LEU A 1 356 ? -45.126 3.719 29.845 1.00 56.03 ? 382 LEU A C 1 ATOM 2703 O O . LEU A 1 356 ? -45.724 4.467 30.627 1.00 49.64 ? 382 LEU A O 1 ATOM 2704 C CB . LEU A 1 356 ? -46.933 2.083 29.417 1.00 55.84 ? 382 LEU A CB 1 ATOM 2705 C CG . LEU A 1 356 ? -47.362 2.558 28.017 1.00 50.61 ? 382 LEU A CG 1 ATOM 2706 C CD1 . LEU A 1 356 ? -46.741 1.672 26.942 1.00 49.77 ? 382 LEU A CD1 1 ATOM 2707 C CD2 . LEU A 1 356 ? -48.894 2.537 27.902 1.00 48.16 ? 382 LEU A CD2 1 ATOM 2708 N N . ARG A 1 357 ? -44.124 4.111 29.069 1.00 58.48 ? 383 ARG A N 1 ATOM 2709 C CA . ARG A 1 357 ? -43.677 5.494 29.006 1.00 69.91 ? 383 ARG A CA 1 ATOM 2710 C C . ARG A 1 357 ? -44.126 6.148 27.695 1.00 67.76 ? 383 ARG A C 1 ATOM 2711 O O . ARG A 1 357 ? -44.262 5.467 26.680 1.00 69.86 ? 383 ARG A O 1 ATOM 2712 C CB . ARG A 1 357 ? -42.168 5.529 29.056 1.00 76.14 ? 383 ARG A CB 1 ATOM 2713 C CG . ARG A 1 357 ? -41.568 4.892 30.281 1.00 84.11 ? 383 ARG A CG 1 ATOM 2714 C CD . ARG A 1 357 ? -40.062 4.904 30.156 1.00 92.60 ? 383 ARG A CD 1 ATOM 2715 N NE . ARG A 1 357 ? -39.619 4.169 28.971 1.00 86.89 ? 383 ARG A NE 1 ATOM 2716 C CZ . ARG A 1 357 ? -38.347 3.999 28.633 1.00 86.33 ? 383 ARG A CZ 1 ATOM 2717 N NH1 . ARG A 1 357 ? -37.376 4.477 29.407 1.00 91.00 ? 383 ARG A NH1 1 ATOM 2718 N NH2 . ARG A 1 357 ? -38.042 3.310 27.547 1.00 81.33 ? 383 ARG A NH2 1 ATOM 2719 N N . GLU A 1 358 ? -44.201 7.480 27.684 1.00 76.96 ? 384 GLU A N 1 ATOM 2720 C CA . GLU A 1 358 ? -44.634 8.223 26.486 1.00 74.33 ? 384 GLU A CA 1 ATOM 2721 C C . GLU A 1 358 ? -43.800 7.883 25.246 1.00 66.01 ? 384 GLU A C 1 ATOM 2722 O O . GLU A 1 358 ? -44.349 7.658 24.168 1.00 80.22 ? 384 GLU A O 1 ATOM 2723 C CB . GLU A 1 358 ? -44.692 9.737 26.764 1.00 85.91 ? 384 GLU A CB 1 ATOM 2724 C CG . GLU A 1 358 ? -45.342 10.554 25.642 1.00 108.29 ? 384 GLU A CG 1 ATOM 2725 C CD . GLU A 1 358 ? -45.771 11.974 26.052 1.00 111.63 ? 384 GLU A CD 1 ATOM 2726 O OE1 . GLU A 1 358 ? -45.473 12.420 27.194 1.00 98.21 ? 384 GLU A OE1 1 ATOM 2727 O OE2 . GLU A 1 358 ? -46.476 12.623 25.233 1.00 116.84 ? 384 GLU A OE2 1 ATOM 2728 N N . ASP A 1 359 ? -42.500 7.720 25.417 1.00 67.69 ? 385 ASP A N 1 ATOM 2729 C CA . ASP A 1 359 ? -41.629 7.389 24.288 1.00 72.42 ? 385 ASP A CA 1 ATOM 2730 C C . ASP A 1 359 ? -41.881 6.017 23.702 1.00 68.12 ? 385 ASP A C 1 ATOM 2731 O O . ASP A 1 359 ? -41.717 5.813 22.501 1.00 73.38 ? 385 ASP A O 1 ATOM 2732 C CB . ASP A 1 359 ? -40.149 7.529 24.674 1.00 80.28 ? 385 ASP A CB 1 ATOM 2733 C CG . ASP A 1 359 ? -39.707 8.990 24.831 1.00 94.00 ? 385 ASP A CG 1 ATOM 2734 O OD1 . ASP A 1 359 ? -38.663 9.210 25.479 1.00 106.15 ? 385 ASP A OD1 1 ATOM 2735 O OD2 . ASP A 1 359 ? -40.399 9.917 24.324 1.00 88.89 ? 385 ASP A OD2 1 ATOM 2736 N N . ASP A 1 360 ? -42.276 5.075 24.547 1.00 71.11 ? 386 ASP A N 1 ATOM 2737 C CA . ASP A 1 360 ? -42.544 3.702 24.106 1.00 64.24 ? 386 ASP A CA 1 ATOM 2738 C C . ASP A 1 360 ? -43.644 3.641 23.034 1.00 49.86 ? 386 ASP A C 1 ATOM 2739 O O . ASP A 1 360 ? -43.600 2.805 22.162 1.00 51.36 ? 386 ASP A O 1 ATOM 2740 C CB . ASP A 1 360 ? -42.944 2.850 25.312 1.00 81.99 ? 386 ASP A CB 1 ATOM 2741 C CG . ASP A 1 360 ? -41.849 2.776 26.377 1.00 79.67 ? 386 ASP A CG 1 ATOM 2742 O OD1 . ASP A 1 360 ? -40.667 2.633 26.015 1.00 69.24 ? 386 ASP A OD1 1 ATOM 2743 O OD2 . ASP A 1 360 ? -42.192 2.740 27.573 1.00 84.24 ? 386 ASP A OD2 1 ATOM 2744 N N . PHE A 1 361 ? -44.597 4.565 23.083 1.00 43.88 ? 387 PHE A N 1 ATOM 2745 C CA . PHE A 1 361 ? -45.713 4.622 22.127 1.00 46.80 ? 387 PHE A CA 1 ATOM 2746 C C . PHE A 1 361 ? -45.652 5.721 21.090 1.00 54.46 ? 387 PHE A C 1 ATOM 2747 O O . PHE A 1 361 ? -46.676 6.106 20.521 1.00 50.71 ? 387 PHE A O 1 ATOM 2748 C CB . PHE A 1 361 ? -47.022 4.669 22.914 1.00 45.80 ? 387 PHE A CB 1 ATOM 2749 C CG . PHE A 1 361 ? -47.623 3.323 23.140 1.00 54.44 ? 387 PHE A CG 1 ATOM 2750 C CD1 . PHE A 1 361 ? -46.823 2.198 23.235 1.00 53.78 ? 387 PHE A CD1 1 ATOM 2751 C CD2 . PHE A 1 361 ? -48.947 3.213 23.488 1.00 57.04 ? 387 PHE A CD2 1 ATOM 2752 C CE1 . PHE A 1 361 ? -47.386 0.970 23.377 1.00 50.59 ? 387 PHE A CE1 1 ATOM 2753 C CE2 . PHE A 1 361 ? -49.493 1.996 23.776 1.00 48.78 ? 387 PHE A CE2 1 ATOM 2754 C CZ . PHE A 1 361 ? -48.718 0.874 23.701 1.00 50.29 ? 387 PHE A CZ 1 ATOM 2755 N N . GLN A 1 362 ? -44.432 6.127 20.770 1.00 65.59 ? 388 GLN A N 1 ATOM 2756 C CA . GLN A 1 362 ? -44.170 7.198 19.819 1.00 68.83 ? 388 GLN A CA 1 ATOM 2757 C C . GLN A 1 362 ? -44.699 6.827 18.429 1.00 59.50 ? 388 GLN A C 1 ATOM 2758 O O . GLN A 1 362 ? -45.525 7.533 17.869 1.00 51.13 ? 388 GLN A O 1 ATOM 2759 C CB . GLN A 1 362 ? -42.658 7.458 19.763 1.00 89.03 ? 388 GLN A CB 1 ATOM 2760 C CG . GLN A 1 362 ? -42.236 8.699 19.003 1.00 107.31 ? 388 GLN A CG 1 ATOM 2761 C CD . GLN A 1 362 ? -42.586 9.982 19.728 1.00 106.87 ? 388 GLN A CD 1 ATOM 2762 O OE1 . GLN A 1 362 ? -42.581 11.054 19.131 1.00 125.88 ? 388 GLN A OE1 1 ATOM 2763 N NE2 . GLN A 1 362 ? -42.871 9.887 21.023 1.00 97.36 ? 388 GLN A NE2 1 ATOM 2764 N N . PRO A 1 363 ? -44.323 5.651 17.939 1.00 40.29 ? 389 PRO A N 1 ATOM 2765 C CA . PRO A 1 363 ? -44.730 5.223 16.634 1.00 47.38 ? 389 PRO A CA 1 ATOM 2766 C C . PRO A 1 363 ? -46.213 5.242 16.316 1.00 48.16 ? 389 PRO A C 1 ATOM 2767 O O . PRO A 1 363 ? -46.564 5.401 15.150 1.00 65.77 ? 389 PRO A O 1 ATOM 2768 C CB . PRO A 1 363 ? -44.184 3.789 16.555 1.00 53.00 ? 389 PRO A CB 1 ATOM 2769 C CG . PRO A 1 363 ? -43.006 3.777 17.476 1.00 43.12 ? 389 PRO A CG 1 ATOM 2770 C CD . PRO A 1 363 ? -43.506 4.629 18.615 1.00 42.78 ? 389 PRO A CD 1 ATOM 2771 N N . LEU A 1 364 ? -47.062 5.172 17.332 1.00 48.03 ? 390 LEU A N 1 ATOM 2772 C CA . LEU A 1 364 ? -48.522 5.130 17.160 1.00 47.24 ? 390 LEU A CA 1 ATOM 2773 C C . LEU A 1 364 ? -49.243 6.476 17.275 1.00 51.52 ? 390 LEU A C 1 ATOM 2774 O O . LEU A 1 364 ? -50.478 6.591 17.000 1.00 46.39 ? 390 LEU A O 1 ATOM 2775 C CB . LEU A 1 364 ? -49.098 4.219 18.272 1.00 49.44 ? 390 LEU A CB 1 ATOM 2776 C CG . LEU A 1 364 ? -48.564 2.783 18.442 1.00 51.81 ? 390 LEU A CG 1 ATOM 2777 C CD1 . LEU A 1 364 ? -49.090 2.170 19.736 1.00 53.50 ? 390 LEU A CD1 1 ATOM 2778 C CD2 . LEU A 1 364 ? -48.844 1.868 17.264 1.00 48.75 ? 390 LEU A CD2 1 ATOM 2779 N N . MET A 1 365 ? -48.536 7.478 17.777 1.00 52.81 ? 391 MET A N 1 ATOM 2780 C CA . MET A 1 365 ? -49.159 8.783 17.979 1.00 52.69 ? 391 MET A CA 1 ATOM 2781 C C . MET A 1 365 ? -49.526 9.530 16.713 1.00 52.52 ? 391 MET A C 1 ATOM 2782 O O . MET A 1 365 ? -50.278 10.488 16.767 1.00 54.98 ? 391 MET A O 1 ATOM 2783 C CB . MET A 1 365 ? -48.327 9.618 18.931 1.00 60.11 ? 391 MET A CB 1 ATOM 2784 C CG . MET A 1 365 ? -48.421 9.125 20.355 1.00 67.67 ? 391 MET A CG 1 ATOM 2785 S SD . MET A 1 365 ? -47.308 9.889 21.549 1.00 68.03 ? 391 MET A SD 1 ATOM 2786 C CE . MET A 1 365 ? -45.784 9.197 20.982 1.00 77.07 ? 391 MET A CE 1 ATOM 2787 N N . GLN A 1 366 ? -49.146 8.994 15.563 1.00 65.37 ? 392 GLN A N 1 ATOM 2788 C CA . GLN A 1 366 ? -49.474 9.648 14.312 1.00 81.30 ? 392 GLN A CA 1 ATOM 2789 C C . GLN A 1 366 ? -50.532 8.893 13.480 1.00 72.57 ? 392 GLN A C 1 ATOM 2790 O O . GLN A 1 366 ? -51.118 9.455 12.578 1.00 69.76 ? 392 GLN A O 1 ATOM 2791 C CB . GLN A 1 366 ? -48.195 9.874 13.515 1.00 106.07 ? 392 GLN A CB 1 ATOM 2792 C CG . GLN A 1 366 ? -47.460 8.624 13.045 1.00 115.99 ? 392 GLN A CG 1 ATOM 2793 C CD . GLN A 1 366 ? -46.103 8.966 12.445 1.00 123.70 ? 392 GLN A CD 1 ATOM 2794 O OE1 . GLN A 1 366 ? -45.802 8.598 11.310 1.00 131.18 ? 392 GLN A OE1 1 ATOM 2795 N NE2 . GLN A 1 366 ? -45.344 9.795 13.149 1.00 127.86 ? 392 GLN A NE2 1 ATOM 2796 N N . LEU A 1 367 ? -50.793 7.638 13.809 1.00 53.10 ? 393 LEU A N 1 ATOM 2797 C CA . LEU A 1 367 ? -51.771 6.856 13.080 1.00 53.52 ? 393 LEU A CA 1 ATOM 2798 C C . LEU A 1 367 ? -53.121 7.557 13.243 1.00 49.99 ? 393 LEU A C 1 ATOM 2799 O O . LEU A 1 367 ? -53.656 7.599 14.324 1.00 51.80 ? 393 LEU A O 1 ATOM 2800 C CB . LEU A 1 367 ? -51.805 5.439 13.627 1.00 48.36 ? 393 LEU A CB 1 ATOM 2801 C CG . LEU A 1 367 ? -50.431 4.752 13.643 1.00 49.10 ? 393 LEU A CG 1 ATOM 2802 C CD1 . LEU A 1 367 ? -50.526 3.318 14.184 1.00 54.32 ? 393 LEU A CD1 1 ATOM 2803 C CD2 . LEU A 1 367 ? -49.797 4.723 12.274 1.00 50.38 ? 393 LEU A CD2 1 ATOM 2804 N N . PRO A 1 368 ? -53.672 8.107 12.153 1.00 50.77 ? 394 PRO A N 1 ATOM 2805 C CA . PRO A 1 368 ? -54.926 8.872 12.214 1.00 47.56 ? 394 PRO A CA 1 ATOM 2806 C C . PRO A 1 368 ? -56.182 8.160 12.516 1.00 47.96 ? 394 PRO A C 1 ATOM 2807 O O . PRO A 1 368 ? -57.135 8.811 12.870 1.00 55.57 ? 394 PRO A O 1 ATOM 2808 C CB . PRO A 1 368 ? -55.045 9.479 10.815 1.00 45.50 ? 394 PRO A CB 1 ATOM 2809 C CG . PRO A 1 368 ? -54.227 8.605 9.948 1.00 48.10 ? 394 PRO A CG 1 ATOM 2810 C CD . PRO A 1 368 ? -53.108 8.098 10.795 1.00 50.46 ? 394 PRO A CD 1 ATOM 2811 N N . ASN A 1 369 ? -56.253 6.861 12.267 1.00 52.73 ? 395 ASN A N 1 ATOM 2812 C CA . ASN A 1 369 ? -57.484 6.133 12.557 1.00 57.17 ? 395 ASN A CA 1 ATOM 2813 C C . ASN A 1 369 ? -57.411 5.186 13.788 1.00 56.13 ? 395 ASN A C 1 ATOM 2814 O O . ASN A 1 369 ? -58.313 4.398 14.025 1.00 43.73 ? 395 ASN A O 1 ATOM 2815 C CB . ASN A 1 369 ? -57.891 5.349 11.328 1.00 67.86 ? 395 ASN A CB 1 ATOM 2816 C CG . ASN A 1 369 ? -58.252 6.232 10.169 1.00 63.59 ? 395 ASN A CG 1 ATOM 2817 O OD1 . ASN A 1 369 ? -57.716 6.076 9.073 1.00 54.92 ? 395 ASN A OD1 1 ATOM 2818 N ND2 . ASN A 1 369 ? -59.091 7.211 10.415 1.00 75.24 ? 395 ASN A ND2 1 ATOM 2819 N N . LEU A 1 370 ? -56.348 5.262 14.569 1.00 51.79 ? 396 LEU A N 1 ATOM 2820 C CA . LEU A 1 370 ? -56.235 4.393 15.730 1.00 48.72 ? 396 LEU A CA 1 ATOM 2821 C C . LEU A 1 370 ? -57.259 4.783 16.820 1.00 47.45 ? 396 LEU A C 1 ATOM 2822 O O . LEU A 1 370 ? -57.096 5.768 17.498 1.00 49.38 ? 396 LEU A O 1 ATOM 2823 C CB . LEU A 1 370 ? -54.827 4.459 16.263 1.00 45.11 ? 396 LEU A CB 1 ATOM 2824 C CG . LEU A 1 370 ? -54.527 3.544 17.419 1.00 50.19 ? 396 LEU A CG 1 ATOM 2825 C CD1 . LEU A 1 370 ? -54.877 2.121 17.006 1.00 51.38 ? 396 LEU A CD1 1 ATOM 2826 C CD2 . LEU A 1 370 ? -53.059 3.648 17.786 1.00 46.30 ? 396 LEU A CD2 1 ATOM 2827 N N . SER A 1 371 ? -58.347 4.034 16.934 1.00 44.37 ? 397 SER A N 1 ATOM 2828 C CA . SER A 1 371 ? -59.362 4.329 17.928 1.00 48.09 ? 397 SER A CA 1 ATOM 2829 C C . SER A 1 371 ? -59.383 3.374 19.137 1.00 49.30 ? 397 SER A C 1 ATOM 2830 O O . SER A 1 371 ? -59.908 3.729 20.190 1.00 45.69 ? 397 SER A O 1 ATOM 2831 C CB . SER A 1 371 ? -60.709 4.373 17.266 1.00 46.31 ? 397 SER A CB 1 ATOM 2832 O OG . SER A 1 371 ? -60.841 3.253 16.437 1.00 55.43 ? 397 SER A OG 1 ATOM 2833 N N . THR A 1 372 ? -58.733 2.224 19.000 1.00 41.87 ? 398 THR A N 1 ATOM 2834 C CA . THR A 1 372 ? -58.672 1.244 20.053 1.00 42.37 ? 398 THR A CA 1 ATOM 2835 C C . THR A 1 372 ? -57.282 0.702 20.352 1.00 45.52 ? 398 THR A C 1 ATOM 2836 O O . THR A 1 372 ? -56.631 0.118 19.465 1.00 42.88 ? 398 THR A O 1 ATOM 2837 C CB . THR A 1 372 ? -59.479 -0.006 19.665 1.00 51.11 ? 398 THR A CB 1 ATOM 2838 O OG1 . THR A 1 372 ? -60.864 0.305 19.667 1.00 54.09 ? 398 THR A OG1 1 ATOM 2839 C CG2 . THR A 1 372 ? -59.276 -1.105 20.667 1.00 53.11 ? 398 THR A CG2 1 ATOM 2840 N N . ILE A 1 373 ? -56.847 0.877 21.598 1.00 38.82 ? 399 ILE A N 1 ATOM 2841 C CA . ILE A 1 373 ? -55.576 0.327 22.066 1.00 51.18 ? 399 ILE A CA 1 ATOM 2842 C C . ILE A 1 373 ? -55.920 -0.667 23.200 1.00 48.25 ? 399 ILE A C 1 ATOM 2843 O O . ILE A 1 373 ? -56.538 -0.316 24.237 1.00 38.65 ? 399 ILE A O 1 ATOM 2844 C CB . ILE A 1 373 ? -54.582 1.376 22.573 1.00 57.24 ? 399 ILE A CB 1 ATOM 2845 C CG1 . ILE A 1 373 ? -54.085 2.191 21.409 1.00 69.48 ? 399 ILE A CG1 1 ATOM 2846 C CG2 . ILE A 1 373 ? -53.360 0.682 23.166 1.00 60.19 ? 399 ILE A CG2 1 ATOM 2847 C CD1 . ILE A 1 373 ? -53.227 3.371 21.819 1.00 85.17 ? 399 ILE A CD1 1 ATOM 2848 N N . ASN A 1 374 ? -55.543 -1.910 22.981 1.00 46.49 ? 400 ASN A N 1 ATOM 2849 C CA . ASN A 1 374 ? -55.821 -2.970 23.940 1.00 43.98 ? 400 ASN A CA 1 ATOM 2850 C C . ASN A 1 374 ? -54.554 -3.444 24.592 1.00 43.28 ? 400 ASN A C 1 ATOM 2851 O O . ASN A 1 374 ? -53.731 -4.119 23.941 1.00 47.64 ? 400 ASN A O 1 ATOM 2852 C CB . ASN A 1 374 ? -56.472 -4.142 23.229 1.00 45.93 ? 400 ASN A CB 1 ATOM 2853 C CG . ASN A 1 374 ? -56.862 -5.257 24.174 1.00 51.04 ? 400 ASN A CG 1 ATOM 2854 O OD1 . ASN A 1 374 ? -56.623 -5.198 25.403 1.00 42.60 ? 400 ASN A OD1 1 ATOM 2855 N ND2 . ASN A 1 374 ? -57.524 -6.256 23.626 1.00 42.95 ? 400 ASN A ND2 1 ATOM 2856 N N . LEU A 1 375 ? -54.400 -3.084 25.871 1.00 39.12 ? 401 LEU A N 1 ATOM 2857 C CA . LEU A 1 375 ? -53.252 -3.452 26.666 1.00 44.80 ? 401 LEU A CA 1 ATOM 2858 C C . LEU A 1 375 ? -53.668 -4.280 27.867 1.00 45.00 ? 401 LEU A C 1 ATOM 2859 O O . LEU A 1 375 ? -53.018 -4.281 28.890 1.00 47.21 ? 401 LEU A O 1 ATOM 2860 C CB . LEU A 1 375 ? -52.493 -2.221 27.116 1.00 48.88 ? 401 LEU A CB 1 ATOM 2861 C CG . LEU A 1 375 ? -51.734 -1.490 26.024 1.00 49.20 ? 401 LEU A CG 1 ATOM 2862 C CD1 . LEU A 1 375 ? -51.205 -0.178 26.575 1.00 49.99 ? 401 LEU A CD1 1 ATOM 2863 C CD2 . LEU A 1 375 ? -50.620 -2.359 25.485 1.00 47.11 ? 401 LEU A CD2 1 ATOM 2864 N N . GLY A 1 376 ? -54.737 -5.025 27.719 1.00 44.06 ? 402 GLY A N 1 ATOM 2865 C CA . GLY A 1 376 ? -55.187 -5.848 28.781 1.00 40.05 ? 402 GLY A CA 1 ATOM 2866 C C . GLY A 1 376 ? -54.194 -6.952 29.088 1.00 43.46 ? 402 GLY A C 1 ATOM 2867 O O . GLY A 1 376 ? -53.429 -7.377 28.223 1.00 45.62 ? 402 GLY A O 1 ATOM 2868 N N . ILE A 1 377 ? -54.124 -7.311 30.367 1.00 43.20 ? 403 ILE A N 1 ATOM 2869 C CA . ILE A 1 377 ? -53.288 -8.405 30.861 1.00 44.01 ? 403 ILE A CA 1 ATOM 2870 C C . ILE A 1 377 ? -51.837 -8.268 30.564 1.00 37.65 ? 403 ILE A C 1 ATOM 2871 O O . ILE A 1 377 ? -51.243 -9.108 29.939 1.00 39.63 ? 403 ILE A O 1 ATOM 2872 C CB . ILE A 1 377 ? -53.729 -9.755 30.261 1.00 49.72 ? 403 ILE A CB 1 ATOM 2873 C CG1 . ILE A 1 377 ? -55.233 -9.880 30.293 1.00 59.66 ? 403 ILE A CG1 1 ATOM 2874 C CG2 . ILE A 1 377 ? -53.127 -10.908 31.058 1.00 54.31 ? 403 ILE A CG2 1 ATOM 2875 C CD1 . ILE A 1 377 ? -55.714 -11.127 29.608 1.00 69.64 ? 403 ILE A CD1 1 ATOM 2876 N N . ASN A 1 378 ? -51.256 -7.203 31.027 1.00 43.78 ? 404 ASN A N 1 ATOM 2877 C CA . ASN A 1 378 ? -49.849 -6.958 30.814 1.00 47.47 ? 404 ASN A CA 1 ATOM 2878 C C . ASN A 1 378 ? -49.067 -6.777 32.112 1.00 44.55 ? 404 ASN A C 1 ATOM 2879 O O . ASN A 1 378 ? -47.842 -6.816 32.117 1.00 55.81 ? 404 ASN A O 1 ATOM 2880 C CB . ASN A 1 378 ? -49.696 -5.772 29.850 1.00 43.87 ? 404 ASN A CB 1 ATOM 2881 C CG . ASN A 1 378 ? -49.784 -6.201 28.412 1.00 45.37 ? 404 ASN A CG 1 ATOM 2882 O OD1 . ASN A 1 378 ? -48.905 -6.962 27.907 1.00 39.96 ? 404 ASN A OD1 1 ATOM 2883 N ND2 . ASN A 1 378 ? -50.743 -5.625 27.690 1.00 50.29 ? 404 ASN A ND2 1 ATOM 2884 N N . PHE A 1 379 ? -49.799 -6.702 33.204 1.00 43.33 ? 405 PHE A N 1 ATOM 2885 C CA . PHE A 1 379 ? -49.242 -6.547 34.529 1.00 52.49 ? 405 PHE A CA 1 ATOM 2886 C C . PHE A 1 379 ? -48.344 -5.369 34.601 1.00 46.48 ? 405 PHE A C 1 ATOM 2887 O O . PHE A 1 379 ? -47.310 -5.422 35.205 1.00 59.22 ? 405 PHE A O 1 ATOM 2888 C CB . PHE A 1 379 ? -48.539 -7.819 34.960 1.00 47.85 ? 405 PHE A CB 1 ATOM 2889 C CG . PHE A 1 379 ? -49.407 -9.017 34.824 1.00 50.72 ? 405 PHE A CG 1 ATOM 2890 C CD1 . PHE A 1 379 ? -50.408 -9.266 35.751 1.00 58.16 ? 405 PHE A CD1 1 ATOM 2891 C CD2 . PHE A 1 379 ? -49.297 -9.843 33.726 1.00 48.57 ? 405 PHE A CD2 1 ATOM 2892 C CE1 . PHE A 1 379 ? -51.283 -10.320 35.574 1.00 55.93 ? 405 PHE A CE1 1 ATOM 2893 C CE2 . PHE A 1 379 ? -50.134 -10.924 33.569 1.00 50.42 ? 405 PHE A CE2 1 ATOM 2894 C CZ . PHE A 1 379 ? -51.140 -11.155 34.483 1.00 53.94 ? 405 PHE A CZ 1 ATOM 2895 N N . ILE A 1 380 ? -48.864 -4.271 34.095 1.00 50.56 ? 406 ILE A N 1 ATOM 2896 C CA . ILE A 1 380 ? -48.200 -2.996 34.033 1.00 50.50 ? 406 ILE A CA 1 ATOM 2897 C C . ILE A 1 380 ? -48.367 -2.342 35.370 1.00 50.58 ? 406 ILE A C 1 ATOM 2898 O O . ILE A 1 380 ? -49.491 -2.228 35.834 1.00 43.23 ? 406 ILE A O 1 ATOM 2899 C CB . ILE A 1 380 ? -48.886 -2.117 32.951 1.00 52.51 ? 406 ILE A CB 1 ATOM 2900 C CG1 . ILE A 1 380 ? -48.772 -2.814 31.582 1.00 51.01 ? 406 ILE A CG1 1 ATOM 2901 C CG2 . ILE A 1 380 ? -48.242 -0.737 32.879 1.00 46.65 ? 406 ILE A CG2 1 ATOM 2902 C CD1 . ILE A 1 380 ? -49.574 -2.168 30.490 1.00 45.28 ? 406 ILE A CD1 1 ATOM 2903 N N . LYS A 1 381 ? -47.256 -1.835 35.936 1.00 48.04 ? 407 LYS A N 1 ATOM 2904 C CA . LYS A 1 381 ? -47.254 -1.197 37.258 1.00 47.19 ? 407 LYS A CA 1 ATOM 2905 C C . LYS A 1 381 ? -47.338 0.302 37.202 1.00 49.99 ? 407 LYS A C 1 ATOM 2906 O O . LYS A 1 381 ? -47.817 0.966 38.149 1.00 45.15 ? 407 LYS A O 1 ATOM 2907 C CB . LYS A 1 381 ? -45.983 -1.590 38.012 1.00 52.83 ? 407 LYS A CB 1 ATOM 2908 C CG . LYS A 1 381 ? -45.848 -3.094 38.229 1.00 61.38 ? 407 LYS A CG 1 ATOM 2909 C CD . LYS A 1 381 ? -44.660 -3.446 39.091 1.00 63.30 ? 407 LYS A CD 1 ATOM 2910 C CE . LYS A 1 381 ? -44.614 -4.945 39.322 1.00 91.06 ? 407 LYS A CE 1 ATOM 2911 N NZ . LYS A 1 381 ? -43.471 -5.397 40.174 1.00 107.89 ? 407 LYS A NZ 1 ATOM 2912 N N . GLN A 1 382 ? -46.797 0.844 36.125 1.00 49.26 ? 408 GLN A N 1 ATOM 2913 C CA . GLN A 1 382 ? -46.795 2.266 35.909 1.00 52.64 ? 408 GLN A CA 1 ATOM 2914 C C . GLN A 1 382 ? -47.060 2.628 34.460 1.00 52.09 ? 408 GLN A C 1 ATOM 2915 O O . GLN A 1 382 ? -46.550 1.996 33.520 1.00 49.82 ? 408 GLN A O 1 ATOM 2916 C CB . GLN A 1 382 ? -45.445 2.865 36.256 1.00 67.07 ? 408 GLN A CB 1 ATOM 2917 C CG . GLN A 1 382 ? -45.105 2.985 37.710 1.00 88.01 ? 408 GLN A CG 1 ATOM 2918 C CD . GLN A 1 382 ? -43.759 3.663 37.884 1.00 110.30 ? 408 GLN A CD 1 ATOM 2919 O OE1 . GLN A 1 382 ? -42.863 3.512 37.050 1.00 121.08 ? 408 GLN A OE1 1 ATOM 2920 N NE2 . GLN A 1 382 ? -43.599 4.391 38.976 1.00 129.51 ? 408 GLN A NE2 1 ATOM 2921 N N . ILE A 1 383 ? -47.755 3.736 34.314 1.00 43.80 ? 409 ILE A N 1 ATOM 2922 C CA . ILE A 1 383 ? -48.087 4.290 33.049 1.00 55.31 ? 409 ILE A CA 1 ATOM 2923 C C . ILE A 1 383 ? -47.986 5.798 33.080 1.00 48.78 ? 409 ILE A C 1 ATOM 2924 O O . ILE A 1 383 ? -48.501 6.438 33.982 1.00 41.99 ? 409 ILE A O 1 ATOM 2925 C CB . ILE A 1 383 ? -49.554 3.963 32.653 1.00 58.39 ? 409 ILE A CB 1 ATOM 2926 C CG1 . ILE A 1 383 ? -49.692 2.482 32.349 1.00 63.14 ? 409 ILE A CG1 1 ATOM 2927 C CG2 . ILE A 1 383 ? -49.933 4.698 31.380 1.00 62.01 ? 409 ILE A CG2 1 ATOM 2928 C CD1 . ILE A 1 383 ? -51.067 2.076 31.871 1.00 64.48 ? 409 ILE A CD1 1 ATOM 2929 N N . ASP A 1 384 ? -47.381 6.389 32.067 1.00 58.53 ? 410 ASP A N 1 ATOM 2930 C CA . ASP A 1 384 ? -47.353 7.846 32.015 1.00 59.17 ? 410 ASP A CA 1 ATOM 2931 C C . ASP A 1 384 ? -48.657 8.172 31.246 1.00 54.82 ? 410 ASP A C 1 ATOM 2932 O O . ASP A 1 384 ? -48.695 8.094 30.023 1.00 54.90 ? 410 ASP A O 1 ATOM 2933 C CB . ASP A 1 384 ? -46.097 8.343 31.296 1.00 70.16 ? 410 ASP A CB 1 ATOM 2934 C CG . ASP A 1 384 ? -45.959 9.883 31.317 1.00 96.62 ? 410 ASP A CG 1 ATOM 2935 O OD1 . ASP A 1 384 ? -46.825 10.588 31.916 1.00 84.70 ? 410 ASP A OD1 1 ATOM 2936 O OD2 . ASP A 1 384 ? -44.968 10.380 30.727 1.00 107.71 ? 410 ASP A OD2 1 ATOM 2937 N N . PHE A 1 385 ? -49.749 8.421 31.960 1.00 51.07 ? 411 PHE A N 1 ATOM 2938 C CA . PHE A 1 385 ? -51.050 8.705 31.291 1.00 53.98 ? 411 PHE A CA 1 ATOM 2939 C C . PHE A 1 385 ? -51.098 9.864 30.327 1.00 60.84 ? 411 PHE A C 1 ATOM 2940 O O . PHE A 1 385 ? -51.966 9.879 29.456 1.00 65.47 ? 411 PHE A O 1 ATOM 2941 C CB . PHE A 1 385 ? -52.229 8.854 32.274 1.00 53.95 ? 411 PHE A CB 1 ATOM 2942 C CG . PHE A 1 385 ? -52.672 7.569 32.890 1.00 66.62 ? 411 PHE A CG 1 ATOM 2943 C CD1 . PHE A 1 385 ? -53.505 6.714 32.189 1.00 67.29 ? 411 PHE A CD1 1 ATOM 2944 C CD2 . PHE A 1 385 ? -52.253 7.200 34.168 1.00 75.47 ? 411 PHE A CD2 1 ATOM 2945 C CE1 . PHE A 1 385 ? -53.922 5.521 32.752 1.00 68.07 ? 411 PHE A CE1 1 ATOM 2946 C CE2 . PHE A 1 385 ? -52.662 6.004 34.733 1.00 79.45 ? 411 PHE A CE2 1 ATOM 2947 C CZ . PHE A 1 385 ? -53.502 5.166 34.026 1.00 81.68 ? 411 PHE A CZ 1 ATOM 2948 N N . LYS A 1 386 ? -50.221 10.855 30.458 1.00 72.39 ? 412 LYS A N 1 ATOM 2949 C CA . LYS A 1 386 ? -50.300 11.976 29.501 1.00 80.27 ? 412 LYS A CA 1 ATOM 2950 C C . LYS A 1 386 ? -50.105 11.491 28.079 1.00 58.75 ? 412 LYS A C 1 ATOM 2951 O O . LYS A 1 386 ? -50.622 12.084 27.173 1.00 60.38 ? 412 LYS A O 1 ATOM 2952 C CB . LYS A 1 386 ? -49.288 13.099 29.772 1.00 89.43 ? 412 LYS A CB 1 ATOM 2953 C CG . LYS A 1 386 ? -47.822 12.723 29.601 1.00 112.68 ? 412 LYS A CG 1 ATOM 2954 C CD . LYS A 1 386 ? -46.925 13.956 29.681 1.00 139.99 ? 412 LYS A CD 1 ATOM 2955 C CE . LYS A 1 386 ? -47.098 14.726 30.987 1.00 161.39 ? 412 LYS A CE 1 ATOM 2956 N NZ . LYS A 1 386 ? -46.269 15.964 31.022 1.00 174.98 ? 412 LYS A NZ 1 ATOM 2957 N N . LEU A 1 387 ? -49.433 10.361 27.895 1.00 54.24 ? 413 LEU A N 1 ATOM 2958 C CA . LEU A 1 387 ? -49.180 9.863 26.559 1.00 52.44 ? 413 LEU A CA 1 ATOM 2959 C C . LEU A 1 387 ? -50.481 9.660 25.760 1.00 54.56 ? 413 LEU A C 1 ATOM 2960 O O . LEU A 1 387 ? -50.487 9.843 24.555 1.00 54.43 ? 413 LEU A O 1 ATOM 2961 C CB . LEU A 1 387 ? -48.321 8.592 26.587 1.00 51.55 ? 413 LEU A CB 1 ATOM 2962 C CG . LEU A 1 387 ? -48.922 7.239 26.975 1.00 59.65 ? 413 LEU A CG 1 ATOM 2963 C CD1 . LEU A 1 387 ? -49.697 6.717 25.782 1.00 56.44 ? 413 LEU A CD1 1 ATOM 2964 C CD2 . LEU A 1 387 ? -47.837 6.225 27.334 1.00 57.29 ? 413 LEU A CD2 1 ATOM 2965 N N . PHE A 1 388 ? -51.588 9.352 26.427 1.00 53.61 ? 414 PHE A N 1 ATOM 2966 C CA . PHE A 1 388 ? -52.847 9.147 25.702 1.00 54.27 ? 414 PHE A CA 1 ATOM 2967 C C . PHE A 1 388 ? -53.442 10.434 25.108 1.00 62.86 ? 414 PHE A C 1 ATOM 2968 O O . PHE A 1 388 ? -54.227 10.385 24.155 1.00 68.78 ? 414 PHE A O 1 ATOM 2969 C CB . PHE A 1 388 ? -53.878 8.339 26.520 1.00 48.07 ? 414 PHE A CB 1 ATOM 2970 C CG . PHE A 1 388 ? -53.448 6.918 26.768 1.00 52.56 ? 414 PHE A CG 1 ATOM 2971 C CD1 . PHE A 1 388 ? -53.326 6.035 25.711 1.00 51.93 ? 414 PHE A CD1 1 ATOM 2972 C CD2 . PHE A 1 388 ? -53.169 6.456 28.051 1.00 50.74 ? 414 PHE A CD2 1 ATOM 2973 C CE1 . PHE A 1 388 ? -52.851 4.742 25.907 1.00 53.58 ? 414 PHE A CE1 1 ATOM 2974 C CE2 . PHE A 1 388 ? -52.751 5.157 28.259 1.00 53.43 ? 414 PHE A CE2 1 ATOM 2975 C CZ . PHE A 1 388 ? -52.617 4.283 27.188 1.00 51.97 ? 414 PHE A CZ 1 ATOM 2976 N N . GLN A 1 389 ? -53.033 11.582 25.631 1.00 61.95 ? 415 GLN A N 1 ATOM 2977 C CA . GLN A 1 389 ? -53.513 12.854 25.111 1.00 61.46 ? 415 GLN A CA 1 ATOM 2978 C C . GLN A 1 389 ? -52.914 13.131 23.756 1.00 58.02 ? 415 GLN A C 1 ATOM 2979 O O . GLN A 1 389 ? -53.485 13.855 22.983 1.00 57.96 ? 415 GLN A O 1 ATOM 2980 C CB . GLN A 1 389 ? -53.135 14.013 26.015 1.00 59.11 ? 415 GLN A CB 1 ATOM 2981 C CG . GLN A 1 389 ? -53.909 14.108 27.303 1.00 72.13 ? 415 GLN A CG 1 ATOM 2982 C CD . GLN A 1 389 ? -53.361 15.204 28.200 1.00 74.25 ? 415 GLN A CD 1 ATOM 2983 O OE1 . GLN A 1 389 ? -52.210 15.601 28.062 1.00 75.46 ? 415 GLN A OE1 1 ATOM 2984 N NE2 . GLN A 1 389 ? -54.137 15.606 29.193 1.00 81.79 ? 415 GLN A NE2 1 ATOM 2985 N N . ASN A 1 390 ? -51.811 12.486 23.429 1.00 59.02 ? 416 ASN A N 1 ATOM 2986 C CA . ASN A 1 390 ? -51.176 12.749 22.162 1.00 59.65 ? 416 ASN A CA 1 ATOM 2987 C C . ASN A 1 390 ? -51.642 11.813 21.033 1.00 56.50 ? 416 ASN A C 1 ATOM 2988 O O . ASN A 1 390 ? -50.833 11.336 20.236 1.00 67.38 ? 416 ASN A O 1 ATOM 2989 C CB . ASN A 1 390 ? -49.647 12.720 22.350 1.00 67.88 ? 416 ASN A CB 1 ATOM 2990 C CG . ASN A 1 390 ? -48.903 13.397 21.210 1.00 80.95 ? 416 ASN A CG 1 ATOM 2991 O OD1 . ASN A 1 390 ? -49.501 14.017 20.330 1.00 78.95 ? 416 ASN A OD1 1 ATOM 2992 N ND2 . ASN A 1 390 ? -47.602 13.328 21.249 1.00 98.43 ? 416 ASN A ND2 1 ATOM 2993 N N . PHE A 1 391 ? -52.953 11.581 20.950 1.00 54.72 ? 417 PHE A N 1 ATOM 2994 C CA . PHE A 1 391 ? -53.527 10.700 19.913 1.00 48.74 ? 417 PHE A CA 1 ATOM 2995 C C . PHE A 1 391 ? -54.700 11.379 19.220 1.00 56.37 ? 417 PHE A C 1 ATOM 2996 O O . PHE A 1 391 ? -55.608 11.893 19.857 1.00 64.00 ? 417 PHE A O 1 ATOM 2997 C CB . PHE A 1 391 ? -54.010 9.347 20.512 1.00 54.44 ? 417 PHE A CB 1 ATOM 2998 C CG . PHE A 1 391 ? -52.902 8.378 20.842 1.00 47.73 ? 417 PHE A CG 1 ATOM 2999 C CD1 . PHE A 1 391 ? -52.226 8.454 22.019 1.00 56.51 ? 417 PHE A CD1 1 ATOM 3000 C CD2 . PHE A 1 391 ? -52.606 7.354 20.003 1.00 51.29 ? 417 PHE A CD2 1 ATOM 3001 C CE1 . PHE A 1 391 ? -51.188 7.583 22.296 1.00 53.00 ? 417 PHE A CE1 1 ATOM 3002 C CE2 . PHE A 1 391 ? -51.592 6.465 20.289 1.00 55.89 ? 417 PHE A CE2 1 ATOM 3003 C CZ . PHE A 1 391 ? -50.909 6.569 21.466 1.00 49.89 ? 417 PHE A CZ 1 ATOM 3004 N N . SER A 1 392 ? -54.753 11.234 17.915 1.00 57.21 ? 418 SER A N 1 ATOM 3005 C CA . SER A 1 392 ? -55.796 11.852 17.132 1.00 71.58 ? 418 SER A CA 1 ATOM 3006 C C . SER A 1 392 ? -57.194 11.300 17.449 1.00 68.30 ? 418 SER A C 1 ATOM 3007 O O . SER A 1 392 ? -58.087 12.041 17.809 1.00 68.31 ? 418 SER A O 1 ATOM 3008 C CB . SER A 1 392 ? -55.539 11.576 15.624 1.00 81.14 ? 418 SER A CB 1 ATOM 3009 O OG . SER A 1 392 ? -54.172 11.719 15.261 1.00 78.00 ? 418 SER A OG 1 ATOM 3010 N N . ASN A 1 393 ? -57.357 9.981 17.348 1.00 66.17 ? 419 ASN A N 1 ATOM 3011 C CA . ASN A 1 393 ? -58.671 9.366 17.527 1.00 66.55 ? 419 ASN A CA 1 ATOM 3012 C C . ASN A 1 393 ? -58.994 8.305 18.572 1.00 57.52 ? 419 ASN A C 1 ATOM 3013 O O . ASN A 1 393 ? -59.951 7.593 18.385 1.00 49.66 ? 419 ASN A O 1 ATOM 3014 C CB . ASN A 1 393 ? -59.106 8.813 16.168 1.00 72.30 ? 419 ASN A CB 1 ATOM 3015 C CG . ASN A 1 393 ? -59.514 9.896 15.216 1.00 82.08 ? 419 ASN A CG 1 ATOM 3016 O OD1 . ASN A 1 393 ? -60.151 10.865 15.613 1.00 84.82 ? 419 ASN A OD1 1 ATOM 3017 N ND2 . ASN A 1 393 ? -59.275 9.675 13.934 1.00 101.91 ? 419 ASN A ND2 1 ATOM 3018 N N . LEU A 1 394 ? -58.239 8.179 19.653 1.00 58.53 ? 420 LEU A N 1 ATOM 3019 C CA . LEU A 1 394 ? -58.588 7.184 20.657 1.00 47.65 ? 420 LEU A CA 1 ATOM 3020 C C . LEU A 1 394 ? -59.978 7.299 21.233 1.00 50.55 ? 420 LEU A C 1 ATOM 3021 O O . LEU A 1 394 ? -60.368 8.341 21.747 1.00 53.84 ? 420 LEU A O 1 ATOM 3022 C CB . LEU A 1 394 ? -57.643 7.197 21.827 1.00 47.37 ? 420 LEU A CB 1 ATOM 3023 C CG . LEU A 1 394 ? -56.324 6.540 21.558 1.00 55.80 ? 420 LEU A CG 1 ATOM 3024 C CD1 . LEU A 1 394 ? -55.489 6.595 22.819 1.00 55.64 ? 420 LEU A CD1 1 ATOM 3025 C CD2 . LEU A 1 394 ? -56.591 5.103 21.155 1.00 56.42 ? 420 LEU A CD2 1 ATOM 3026 N N . GLU A 1 395 ? -60.717 6.199 21.153 1.00 52.81 ? 421 GLU A N 1 ATOM 3027 C CA . GLU A 1 395 ? -62.038 6.127 21.733 1.00 59.66 ? 421 GLU A CA 1 ATOM 3028 C C . GLU A 1 395 ? -62.091 5.053 22.825 1.00 53.07 ? 421 GLU A C 1 ATOM 3029 O O . GLU A 1 395 ? -62.938 5.123 23.726 1.00 51.32 ? 421 GLU A O 1 ATOM 3030 C CB . GLU A 1 395 ? -63.100 5.893 20.668 1.00 59.61 ? 421 GLU A CB 1 ATOM 3031 C CG . GLU A 1 395 ? -63.301 7.125 19.833 1.00 67.77 ? 421 GLU A CG 1 ATOM 3032 C CD . GLU A 1 395 ? -63.769 8.297 20.681 1.00 85.25 ? 421 GLU A CD 1 ATOM 3033 O OE1 . GLU A 1 395 ? -64.819 8.169 21.386 1.00 84.08 ? 421 GLU A OE1 1 ATOM 3034 O OE2 . GLU A 1 395 ? -63.143 9.378 20.569 1.00 90.72 ? 421 GLU A OE2 1 ATOM 3035 N N . ILE A 1 396 ? -61.156 4.100 22.759 1.00 47.04 ? 422 ILE A N 1 ATOM 3036 C CA . ILE A 1 396 ? -61.085 3.002 23.694 1.00 43.02 ? 422 ILE A CA 1 ATOM 3037 C C . ILE A 1 396 ? -59.697 2.672 24.129 1.00 44.26 ? 422 ILE A C 1 ATOM 3038 O O . ILE A 1 396 ? -58.864 2.250 23.306 1.00 40.61 ? 422 ILE A O 1 ATOM 3039 C CB . ILE A 1 396 ? -61.677 1.745 23.086 1.00 52.25 ? 422 ILE A CB 1 ATOM 3040 C CG1 . ILE A 1 396 ? -63.186 1.936 22.934 1.00 54.58 ? 422 ILE A CG1 1 ATOM 3041 C CG2 . ILE A 1 396 ? -61.412 0.555 24.006 1.00 54.06 ? 422 ILE A CG2 1 ATOM 3042 C CD1 . ILE A 1 396 ? -63.878 0.767 22.311 1.00 54.56 ? 422 ILE A CD1 1 ATOM 3043 N N . ILE A 1 397 ? -59.468 2.839 25.440 1.00 42.31 ? 423 ILE A N 1 ATOM 3044 C CA . ILE A 1 397 ? -58.174 2.553 26.093 1.00 43.57 ? 423 ILE A CA 1 ATOM 3045 C C . ILE A 1 397 ? -58.458 1.389 27.077 1.00 45.75 ? 423 ILE A C 1 ATOM 3046 O O . ILE A 1 397 ? -59.047 1.571 28.153 1.00 36.71 ? 423 ILE A O 1 ATOM 3047 C CB . ILE A 1 397 ? -57.677 3.767 26.869 1.00 46.31 ? 423 ILE A CB 1 ATOM 3048 C CG1 . ILE A 1 397 ? -57.670 5.001 25.958 1.00 53.68 ? 423 ILE A CG1 1 ATOM 3049 C CG2 . ILE A 1 397 ? -56.298 3.485 27.441 1.00 52.70 ? 423 ILE A CG2 1 ATOM 3050 C CD1 . ILE A 1 397 ? -57.240 6.296 26.622 1.00 52.46 ? 423 ILE A CD1 1 ATOM 3051 N N . TYR A 1 398 ? -58.096 0.189 26.673 1.00 45.67 ? 424 TYR A N 1 ATOM 3052 C CA . TYR A 1 398 ? -58.376 -0.967 27.480 1.00 44.20 ? 424 TYR A CA 1 ATOM 3053 C C . TYR A 1 398 ? -57.166 -1.381 28.272 1.00 46.10 ? 424 TYR A C 1 ATOM 3054 O O . TYR A 1 398 ? -56.177 -1.889 27.727 1.00 44.58 ? 424 TYR A O 1 ATOM 3055 C CB . TYR A 1 398 ? -58.887 -2.108 26.579 1.00 48.37 ? 424 TYR A CB 1 ATOM 3056 C CG . TYR A 1 398 ? -59.476 -3.256 27.357 1.00 51.63 ? 424 TYR A CG 1 ATOM 3057 C CD1 . TYR A 1 398 ? -60.732 -3.142 27.914 1.00 52.12 ? 424 TYR A CD1 1 ATOM 3058 C CD2 . TYR A 1 398 ? -58.800 -4.459 27.504 1.00 50.64 ? 424 TYR A CD2 1 ATOM 3059 C CE1 . TYR A 1 398 ? -61.247 -4.132 28.716 1.00 49.32 ? 424 TYR A CE1 1 ATOM 3060 C CE2 . TYR A 1 398 ? -59.332 -5.481 28.248 1.00 48.66 ? 424 TYR A CE2 1 ATOM 3061 C CZ . TYR A 1 398 ? -60.561 -5.313 28.854 1.00 52.46 ? 424 TYR A CZ 1 ATOM 3062 O OH . TYR A 1 398 ? -61.139 -6.332 29.593 1.00 49.97 ? 424 TYR A OH 1 ATOM 3063 N N . LEU A 1 399 ? -57.267 -1.200 29.581 1.00 45.28 ? 425 LEU A N 1 ATOM 3064 C CA . LEU A 1 399 ? -56.184 -1.541 30.491 1.00 46.26 ? 425 LEU A CA 1 ATOM 3065 C C . LEU A 1 399 ? -56.604 -2.537 31.637 1.00 42.82 ? 425 LEU A C 1 ATOM 3066 O O . LEU A 1 399 ? -56.003 -2.566 32.687 1.00 37.64 ? 425 LEU A O 1 ATOM 3067 C CB . LEU A 1 399 ? -55.656 -0.249 31.095 1.00 41.56 ? 425 LEU A CB 1 ATOM 3068 C CG . LEU A 1 399 ? -54.951 0.733 30.189 1.00 45.12 ? 425 LEU A CG 1 ATOM 3069 C CD1 . LEU A 1 399 ? -54.754 2.055 30.905 1.00 45.96 ? 425 LEU A CD1 1 ATOM 3070 C CD2 . LEU A 1 399 ? -53.620 0.198 29.727 1.00 47.55 ? 425 LEU A CD2 1 ATOM 3071 N N . SER A 1 400 ? -57.555 -3.408 31.391 1.00 42.74 ? 426 SER A N 1 ATOM 3072 C CA . SER A 1 400 ? -57.975 -4.315 32.432 1.00 42.40 ? 426 SER A CA 1 ATOM 3073 C C . SER A 1 400 ? -56.902 -5.326 32.739 1.00 41.23 ? 426 SER A C 1 ATOM 3074 O O . SER A 1 400 ? -56.133 -5.715 31.869 1.00 41.51 ? 426 SER A O 1 ATOM 3075 C CB . SER A 1 400 ? -59.242 -5.044 32.032 1.00 44.65 ? 426 SER A CB 1 ATOM 3076 O OG . SER A 1 400 ? -59.770 -5.758 33.130 1.00 49.31 ? 426 SER A OG 1 ATOM 3077 N N . GLU A 1 401 ? -56.835 -5.737 33.993 1.00 40.91 ? 427 GLU A N 1 ATOM 3078 C CA . GLU A 1 401 ? -55.851 -6.727 34.428 1.00 43.83 ? 427 GLU A CA 1 ATOM 3079 C C . GLU A 1 401 ? -54.410 -6.246 34.302 1.00 39.10 ? 427 GLU A C 1 ATOM 3080 O O . GLU A 1 401 ? -53.539 -6.849 33.649 1.00 42.76 ? 427 GLU A O 1 ATOM 3081 C CB . GLU A 1 401 ? -56.036 -8.096 33.767 1.00 38.51 ? 427 GLU A CB 1 ATOM 3082 C CG . GLU A 1 401 ? -57.432 -8.642 33.970 1.00 51.27 ? 427 GLU A CG 1 ATOM 3083 C CD . GLU A 1 401 ? -57.599 -10.078 33.437 1.00 65.74 ? 427 GLU A CD 1 ATOM 3084 O OE1 . GLU A 1 401 ? -56.900 -11.000 33.918 1.00 72.16 ? 427 GLU A OE1 1 ATOM 3085 O OE2 . GLU A 1 401 ? -58.536 -10.318 32.655 1.00 65.71 ? 427 GLU A OE2 1 ATOM 3086 N N . ASN A 1 402 ? -54.179 -5.117 34.898 1.00 41.33 ? 428 ASN A N 1 ATOM 3087 C CA . ASN A 1 402 ? -52.837 -4.580 34.965 1.00 48.96 ? 428 ASN A CA 1 ATOM 3088 C C . ASN A 1 402 ? -52.601 -4.295 36.428 1.00 45.14 ? 428 ASN A C 1 ATOM 3089 O O . ASN A 1 402 ? -53.482 -4.576 37.246 1.00 40.88 ? 428 ASN A O 1 ATOM 3090 C CB . ASN A 1 402 ? -52.678 -3.394 34.031 1.00 40.17 ? 428 ASN A CB 1 ATOM 3091 C CG . ASN A 1 402 ? -52.516 -3.854 32.624 1.00 42.23 ? 428 ASN A CG 1 ATOM 3092 O OD1 . ASN A 1 402 ? -51.458 -4.402 32.272 1.00 38.87 ? 428 ASN A OD1 1 ATOM 3093 N ND2 . ASN A 1 402 ? -53.537 -3.617 31.783 1.00 43.53 ? 428 ASN A ND2 1 ATOM 3094 N N . ARG A 1 403 ? -51.474 -3.694 36.768 1.00 46.42 ? 429 ARG A N 1 ATOM 3095 C CA . ARG A 1 403 ? -51.201 -3.439 38.161 1.00 46.14 ? 429 ARG A CA 1 ATOM 3096 C C . ARG A 1 403 ? -51.103 -1.980 38.569 1.00 49.04 ? 429 ARG A C 1 ATOM 3097 O O . ARG A 1 403 ? -50.253 -1.613 39.390 1.00 41.78 ? 429 ARG A O 1 ATOM 3098 C CB . ARG A 1 403 ? -49.959 -4.199 38.586 1.00 46.63 ? 429 ARG A CB 1 ATOM 3099 C CG . ARG A 1 403 ? -50.026 -5.688 38.238 1.00 53.07 ? 429 ARG A CG 1 ATOM 3100 C CD . ARG A 1 403 ? -49.253 -6.437 39.301 1.00 70.02 ? 429 ARG A CD 1 ATOM 3101 N NE . ARG A 1 403 ? -50.010 -6.255 40.545 1.00 69.36 ? 429 ARG A NE 1 ATOM 3102 C CZ . ARG A 1 403 ? -49.560 -6.477 41.767 1.00 66.32 ? 429 ARG A CZ 1 ATOM 3103 N NH1 . ARG A 1 403 ? -48.272 -6.764 41.985 1.00 80.02 ? 429 ARG A NH1 1 ATOM 3104 N NH2 . ARG A 1 403 ? -50.380 -6.248 42.777 1.00 67.25 ? 429 ARG A NH2 1 ATOM 3105 N N . ILE A 1 404 ? -51.988 -1.152 38.029 1.00 46.45 ? 430 ILE A N 1 ATOM 3106 C CA . ILE A 1 404 ? -51.980 0.256 38.392 1.00 51.22 ? 430 ILE A CA 1 ATOM 3107 C C . ILE A 1 404 ? -52.360 0.336 39.862 1.00 42.87 ? 430 ILE A C 1 ATOM 3108 O O . ILE A 1 404 ? -53.384 -0.195 40.268 1.00 44.98 ? 430 ILE A O 1 ATOM 3109 C CB . ILE A 1 404 ? -52.907 1.134 37.486 1.00 49.78 ? 430 ILE A CB 1 ATOM 3110 C CG1 . ILE A 1 404 ? -52.237 1.428 36.178 1.00 50.40 ? 430 ILE A CG1 1 ATOM 3111 C CG2 . ILE A 1 404 ? -53.068 2.534 38.051 1.00 49.23 ? 430 ILE A CG2 1 ATOM 3112 C CD1 . ILE A 1 404 ? -51.850 0.215 35.447 1.00 61.14 ? 430 ILE A CD1 1 ATOM 3113 N N . SER A 1 405 ? -51.584 1.130 40.593 1.00 50.28 ? 431 SER A N 1 ATOM 3114 C CA . SER A 1 405 ? -51.718 1.359 42.032 1.00 50.57 ? 431 SER A CA 1 ATOM 3115 C C . SER A 1 405 ? -52.169 2.765 42.285 1.00 52.92 ? 431 SER A C 1 ATOM 3116 O O . SER A 1 405 ? -52.071 3.606 41.403 1.00 54.99 ? 431 SER A O 1 ATOM 3117 C CB . SER A 1 405 ? -50.337 1.344 42.637 1.00 46.05 ? 431 SER A CB 1 ATOM 3118 O OG . SER A 1 405 ? -49.571 0.336 42.023 1.00 54.06 ? 431 SER A OG 1 ATOM 3119 N N . PRO A 1 406 ? -52.484 3.067 43.543 1.00 45.08 ? 432 PRO A N 1 ATOM 3120 C CA . PRO A 1 406 ? -52.885 4.407 43.873 1.00 52.39 ? 432 PRO A CA 1 ATOM 3121 C C . PRO A 1 406 ? -51.689 5.310 43.654 1.00 57.15 ? 432 PRO A C 1 ATOM 3122 O O . PRO A 1 406 ? -50.571 4.899 43.929 1.00 51.16 ? 432 PRO A O 1 ATOM 3123 C CB . PRO A 1 406 ? -53.238 4.327 45.369 1.00 45.08 ? 432 PRO A CB 1 ATOM 3124 C CG . PRO A 1 406 ? -53.523 2.903 45.615 1.00 44.57 ? 432 PRO A CG 1 ATOM 3125 C CD . PRO A 1 406 ? -52.639 2.148 44.670 1.00 43.59 ? 432 PRO A CD 1 ATOM 3126 N N . LEU A 1 407 ? -51.939 6.511 43.127 1.00 73.47 ? 433 LEU A N 1 ATOM 3127 C CA . LEU A 1 407 ? -50.893 7.491 42.825 1.00 80.41 ? 433 LEU A CA 1 ATOM 3128 C C . LEU A 1 407 ? -50.913 8.662 43.819 1.00 94.03 ? 433 LEU A C 1 ATOM 3129 O O . LEU A 1 407 ? -51.854 9.462 43.854 1.00 82.62 ? 433 LEU A O 1 ATOM 3130 C CB . LEU A 1 407 ? -51.028 7.985 41.363 1.00 76.14 ? 433 LEU A CB 1 ATOM 3131 C CG . LEU A 1 407 ? -50.878 6.932 40.227 1.00 81.48 ? 433 LEU A CG 1 ATOM 3132 C CD1 . LEU A 1 407 ? -51.236 7.461 38.833 1.00 74.68 ? 433 LEU A CD1 1 ATOM 3133 C CD2 . LEU A 1 407 ? -49.486 6.306 40.188 1.00 80.41 ? 433 LEU A CD2 1 ATOM 3134 N N . VAL A 1 408 ? -49.850 8.731 44.621 1.00 118.01 ? 434 VAL A N 1 ATOM 3135 C CA . VAL A 1 408 ? -49.663 9.762 45.643 1.00 121.47 ? 434 VAL A CA 1 ATOM 3136 C C . VAL A 1 408 ? -48.529 10.715 45.249 1.00 113.63 ? 434 VAL A C 1 ATOM 3137 O O . VAL A 1 408 ? -48.738 11.700 44.544 1.00 93.21 ? 434 VAL A O 1 ATOM 3138 C CB . VAL A 1 408 ? -49.299 9.113 46.997 1.00 119.23 ? 434 VAL A CB 1 ATOM 3139 C CG1 . VAL A 1 408 ? -48.978 10.175 48.039 1.00 123.25 ? 434 VAL A CG1 1 ATOM 3140 C CG2 . VAL A 1 408 ? -50.423 8.203 47.467 1.00 107.50 ? 434 VAL A CG2 1 ATOM 3141 N N . ASN A 1 417 ? -38.742 -5.549 39.435 1.00 107.90 ? 443 ASN A N 1 ATOM 3142 C CA . ASN A 1 417 ? -38.457 -6.987 39.391 1.00 110.64 ? 443 ASN A CA 1 ATOM 3143 C C . ASN A 1 417 ? -37.626 -7.324 38.150 1.00 105.95 ? 443 ASN A C 1 ATOM 3144 O O . ASN A 1 417 ? -37.115 -6.429 37.469 1.00 114.03 ? 443 ASN A O 1 ATOM 3145 C CB . ASN A 1 417 ? -39.767 -7.785 39.356 1.00 95.54 ? 443 ASN A CB 1 ATOM 3146 C CG . ASN A 1 417 ? -40.728 -7.379 40.454 1.00 91.99 ? 443 ASN A CG 1 ATOM 3147 O OD1 . ASN A 1 417 ? -40.462 -6.476 41.240 1.00 104.84 ? 443 ASN A OD1 1 ATOM 3148 N ND2 . ASN A 1 417 ? -41.851 -8.044 40.506 1.00 92.74 ? 443 ASN A ND2 1 ATOM 3149 N N . SER A 1 418 ? -37.516 -8.613 37.847 1.00 103.19 ? 444 SER A N 1 ATOM 3150 C CA . SER A 1 418 ? -36.749 -9.075 36.688 1.00 101.01 ? 444 SER A CA 1 ATOM 3151 C C . SER A 1 418 ? -37.490 -10.188 35.927 1.00 94.76 ? 444 SER A C 1 ATOM 3152 O O . SER A 1 418 ? -37.319 -10.348 34.715 1.00 96.16 ? 444 SER A O 1 ATOM 3153 C CB . SER A 1 418 ? -35.402 -9.618 37.175 1.00 101.16 ? 444 SER A CB 1 ATOM 3154 O OG . SER A 1 418 ? -34.749 -8.683 38.032 1.00 94.76 ? 444 SER A OG 1 ATOM 3155 N N . SER A 1 419 ? -38.363 -10.897 36.646 1.00 91.06 ? 445 SER A N 1 ATOM 3156 C CA . SER A 1 419 ? -39.124 -12.002 36.110 1.00 79.87 ? 445 SER A CA 1 ATOM 3157 C C . SER A 1 419 ? -40.560 -11.996 36.580 1.00 77.85 ? 445 SER A C 1 ATOM 3158 O O . SER A 1 419 ? -40.932 -11.169 37.414 1.00 76.49 ? 445 SER A O 1 ATOM 3159 C CB . SER A 1 419 ? -38.493 -13.297 36.587 1.00 92.25 ? 445 SER A CB 1 ATOM 3160 O OG . SER A 1 419 ? -39.262 -14.408 36.149 1.00 111.37 ? 445 SER A OG 1 ATOM 3161 N N . SER A 1 420 ? -41.349 -12.954 36.072 1.00 84.20 ? 446 SER A N 1 ATOM 3162 C CA . SER A 1 420 ? -42.782 -13.099 36.431 1.00 100.76 ? 446 SER A CA 1 ATOM 3163 C C . SER A 1 420 ? -43.253 -14.531 36.150 1.00 102.52 ? 446 SER A C 1 ATOM 3164 O O . SER A 1 420 ? -42.508 -15.351 35.608 1.00 81.94 ? 446 SER A O 1 ATOM 3165 C CB . SER A 1 420 ? -43.665 -12.108 35.621 1.00 106.07 ? 446 SER A CB 1 ATOM 3166 O OG . SER A 1 420 ? -45.046 -12.145 36.009 1.00 91.67 ? 446 SER A OG 1 ATOM 3167 N N . PHE A 1 421 ? -44.473 -14.838 36.579 1.00 108.41 ? 447 PHE A N 1 ATOM 3168 C CA . PHE A 1 421 ? -45.055 -16.143 36.331 1.00 122.82 ? 447 PHE A CA 1 ATOM 3169 C C . PHE A 1 421 ? -46.467 -16.009 35.754 1.00 129.15 ? 447 PHE A C 1 ATOM 3170 O O . PHE A 1 421 ? -47.458 -16.123 36.478 1.00 150.04 ? 447 PHE A O 1 ATOM 3171 C CB . PHE A 1 421 ? -45.071 -17.035 37.575 1.00 140.59 ? 447 PHE A CB 1 ATOM 3172 C CG . PHE A 1 421 ? -45.728 -18.376 37.338 1.00 167.79 ? 447 PHE A CG 1 ATOM 3173 C CD1 . PHE A 1 421 ? -44.999 -19.446 36.825 1.00 173.93 ? 447 PHE A CD1 1 ATOM 3174 C CD2 . PHE A 1 421 ? -47.091 -18.549 37.569 1.00 171.78 ? 447 PHE A CD2 1 ATOM 3175 C CE1 . PHE A 1 421 ? -45.611 -20.665 36.575 1.00 176.09 ? 447 PHE A CE1 1 ATOM 3176 C CE2 . PHE A 1 421 ? -47.705 -19.763 37.317 1.00 177.32 ? 447 PHE A CE2 1 ATOM 3177 C CZ . PHE A 1 421 ? -46.963 -20.825 36.826 1.00 175.84 ? 447 PHE A CZ 1 ATOM 3178 N N . GLN A 1 422 ? -46.541 -15.667 34.469 1.00 115.53 ? 448 GLN A N 1 ATOM 3179 C CA . GLN A 1 422 ? -47.815 -15.557 33.760 1.00 100.81 ? 448 GLN A CA 1 ATOM 3180 C C . GLN A 1 422 ? -48.093 -16.914 33.113 1.00 103.15 ? 448 GLN A C 1 ATOM 3181 O O . GLN A 1 422 ? -47.200 -17.520 32.522 1.00 83.94 ? 448 GLN A O 1 ATOM 3182 C CB . GLN A 1 422 ? -47.783 -14.426 32.698 1.00 104.37 ? 448 GLN A CB 1 ATOM 3183 C CG . GLN A 1 422 ? -48.916 -14.419 31.631 1.00 89.90 ? 448 GLN A CG 1 ATOM 3184 C CD . GLN A 1 422 ? -50.339 -14.318 32.186 1.00 91.23 ? 448 GLN A CD 1 ATOM 3185 O OE1 . GLN A 1 422 ? -51.316 -14.364 31.433 1.00 72.33 ? 448 GLN A OE1 1 ATOM 3186 N NE2 . GLN A 1 422 ? -50.462 -14.191 33.497 1.00 84.73 ? 448 GLN A NE2 1 ATOM 3187 N N . ARG A 1 423 ? -49.301 -17.426 33.333 1.00 110.80 ? 449 ARG A N 1 ATOM 3188 C CA . ARG A 1 423 ? -49.737 -18.696 32.766 1.00 116.98 ? 449 ARG A CA 1 ATOM 3189 C C . ARG A 1 423 ? -51.089 -18.444 32.128 1.00 118.43 ? 449 ARG A C 1 ATOM 3190 O O . ARG A 1 423 ? -52.028 -18.016 32.806 1.00 119.32 ? 449 ARG A O 1 ATOM 3191 C CB . ARG A 1 423 ? -49.857 -19.791 33.843 1.00 140.13 ? 449 ARG A CB 1 ATOM 3192 C CG . ARG A 1 423 ? -50.736 -19.419 35.038 1.00 151.06 ? 449 ARG A CG 1 ATOM 3193 C CD . ARG A 1 423 ? -50.980 -20.595 35.976 1.00 149.64 ? 449 ARG A CD 1 ATOM 3194 N NE . ARG A 1 423 ? -51.687 -20.189 37.197 1.00 142.67 ? 449 ARG A NE 1 ATOM 3195 C CZ . ARG A 1 423 ? -52.118 -21.027 38.144 1.00 142.38 ? 449 ARG A CZ 1 ATOM 3196 N NH1 . ARG A 1 423 ? -52.004 -22.342 37.987 1.00 135.52 ? 449 ARG A NH1 1 ATOM 3197 N NH2 . ARG A 1 423 ? -52.729 -20.553 39.225 1.00 142.78 ? 449 ARG A NH2 1 ATOM 3198 N N . HIS A 1 424 ? -51.178 -18.641 30.818 1.00 102.85 ? 450 HIS A N 1 ATOM 3199 C CA . HIS A 1 424 ? -52.442 -18.424 30.119 1.00 113.65 ? 450 HIS A CA 1 ATOM 3200 C C . HIS A 1 424 ? -53.294 -19.716 30.082 1.00 112.11 ? 450 HIS A C 1 ATOM 3201 O O . HIS A 1 424 ? -52.750 -20.815 30.061 1.00 112.75 ? 450 HIS A O 1 ATOM 3202 C CB . HIS A 1 424 ? -52.189 -17.840 28.707 1.00 101.83 ? 450 HIS A CB 1 ATOM 3203 C CG . HIS A 1 424 ? -53.434 -17.691 27.886 1.00 100.84 ? 450 HIS A CG 1 ATOM 3204 N ND1 . HIS A 1 424 ? -54.359 -16.691 28.107 1.00 94.37 ? 450 HIS A ND1 1 ATOM 3205 C CD2 . HIS A 1 424 ? -53.910 -18.420 26.845 1.00 95.42 ? 450 HIS A CD2 1 ATOM 3206 C CE1 . HIS A 1 424 ? -55.369 -16.833 27.264 1.00 95.33 ? 450 HIS A CE1 1 ATOM 3207 N NE2 . HIS A 1 424 ? -55.122 -17.875 26.488 1.00 92.44 ? 450 HIS A NE2 1 ATOM 3208 N N . ILE A 1 425 ? -54.622 -19.570 30.175 1.00 113.62 ? 451 ILE A N 1 ATOM 3209 C CA . ILE A 1 425 ? -55.550 -20.721 30.139 1.00 119.90 ? 451 ILE A CA 1 ATOM 3210 C C . ILE A 1 425 ? -56.864 -20.340 29.464 1.00 98.40 ? 451 ILE A C 1 ATOM 3211 O O . ILE A 1 425 ? -56.976 -20.401 28.250 1.00 90.48 ? 451 ILE A O 1 ATOM 3212 C CB . ILE A 1 425 ? -55.835 -21.317 31.556 1.00 132.80 ? 451 ILE A CB 1 ATOM 3213 C CG1 . ILE A 1 425 ? -56.671 -20.373 32.456 1.00 123.55 ? 451 ILE A CG1 1 ATOM 3214 C CG2 . ILE A 1 425 ? -54.536 -21.732 32.241 1.00 137.67 ? 451 ILE A CG2 1 ATOM 3215 C CD1 . ILE A 1 425 ? -58.129 -20.201 32.054 1.00 119.19 ? 451 ILE A CD1 1 ATOM 3216 N N . PRO A 1 437 ? -68.489 -24.341 17.749 1.00 115.21 ? 463 PRO A N 1 ATOM 3217 C CA . PRO A 1 437 ? -68.011 -23.100 17.156 1.00 128.28 ? 463 PRO A CA 1 ATOM 3218 C C . PRO A 1 437 ? -67.054 -23.325 15.968 1.00 134.26 ? 463 PRO A C 1 ATOM 3219 O O . PRO A 1 437 ? -66.108 -24.101 16.104 1.00 129.00 ? 463 PRO A O 1 ATOM 3220 C CB . PRO A 1 437 ? -67.266 -22.440 18.319 1.00 115.88 ? 463 PRO A CB 1 ATOM 3221 C CG . PRO A 1 437 ? -68.000 -22.886 19.532 1.00 110.89 ? 463 PRO A CG 1 ATOM 3222 C CD . PRO A 1 437 ? -68.490 -24.279 19.225 1.00 117.05 ? 463 PRO A CD 1 ATOM 3223 N N . HIS A 1 438 ? -67.317 -22.748 14.790 1.00 126.65 ? 464 HIS A N 1 ATOM 3224 C CA . HIS A 1 438 ? -68.483 -21.899 14.461 1.00 134.42 ? 464 HIS A CA 1 ATOM 3225 C C . HIS A 1 438 ? -68.324 -20.460 15.008 1.00 129.24 ? 464 HIS A C 1 ATOM 3226 O O . HIS A 1 438 ? -69.171 -19.582 14.769 1.00 105.55 ? 464 HIS A O 1 ATOM 3227 C CB . HIS A 1 438 ? -69.785 -22.516 14.968 1.00 140.45 ? 464 HIS A CB 1 ATOM 3228 C CG . HIS A 1 438 ? -70.914 -22.388 14.002 1.00 143.05 ? 464 HIS A CG 1 ATOM 3229 N ND1 . HIS A 1 438 ? -71.572 -21.203 13.744 1.00 148.65 ? 464 HIS A ND1 1 ATOM 3230 C CD2 . HIS A 1 438 ? -71.490 -23.320 13.208 1.00 137.86 ? 464 HIS A CD2 1 ATOM 3231 C CE1 . HIS A 1 438 ? -72.496 -21.412 12.821 1.00 148.17 ? 464 HIS A CE1 1 ATOM 3232 N NE2 . HIS A 1 438 ? -72.469 -22.689 12.485 1.00 148.21 ? 464 HIS A NE2 1 ATOM 3233 N N . SER A 1 439 ? -67.280 -20.268 15.793 1.00 132.13 ? 465 SER A N 1 ATOM 3234 C CA . SER A 1 439 ? -66.974 -18.973 16.350 1.00 120.46 ? 465 SER A CA 1 ATOM 3235 C C . SER A 1 439 ? -65.491 -18.907 16.630 1.00 121.11 ? 465 SER A C 1 ATOM 3236 O O . SER A 1 439 ? -64.821 -19.929 16.662 1.00 113.01 ? 465 SER A O 1 ATOM 3237 C CB . SER A 1 439 ? -67.803 -18.705 17.603 1.00 118.03 ? 465 SER A CB 1 ATOM 3238 O OG . SER A 1 439 ? -67.106 -19.017 18.791 1.00 126.04 ? 465 SER A OG 1 ATOM 3239 N N . ASN A 1 440 ? -65.019 -17.681 16.794 1.00 120.09 ? 466 ASN A N 1 ATOM 3240 C CA . ASN A 1 440 ? -63.637 -17.307 17.065 1.00 120.96 ? 466 ASN A CA 1 ATOM 3241 C C . ASN A 1 440 ? -63.284 -16.092 16.231 1.00 135.52 ? 466 ASN A C 1 ATOM 3242 O O . ASN A 1 440 ? -64.102 -15.201 16.072 1.00 161.45 ? 466 ASN A O 1 ATOM 3243 C CB . ASN A 1 440 ? -62.604 -18.435 16.977 1.00 107.38 ? 466 ASN A CB 1 ATOM 3244 C CG . ASN A 1 440 ? -61.983 -18.767 18.322 1.00 99.77 ? 466 ASN A CG 1 ATOM 3245 O OD1 . ASN A 1 440 ? -61.221 -19.714 18.437 1.00 98.75 ? 466 ASN A OD1 1 ATOM 3246 N ND2 . ASN A 1 440 ? -62.306 -17.993 19.340 1.00 97.05 ? 466 ASN A ND2 1 ATOM 3247 N N . PHE A 1 441 ? -62.092 -16.103 15.663 1.00 132.97 ? 467 PHE A N 1 ATOM 3248 C CA . PHE A 1 441 ? -61.241 -14.978 15.353 1.00 137.61 ? 467 PHE A CA 1 ATOM 3249 C C . PHE A 1 441 ? -60.108 -15.014 16.368 1.00 142.88 ? 467 PHE A C 1 ATOM 3250 O O . PHE A 1 441 ? -59.018 -14.549 16.073 1.00 143.72 ? 467 PHE A O 1 ATOM 3251 C CB . PHE A 1 441 ? -61.956 -13.649 15.562 1.00 139.46 ? 467 PHE A CB 1 ATOM 3252 C CG . PHE A 1 441 ? -62.735 -13.136 14.380 1.00 127.66 ? 467 PHE A CG 1 ATOM 3253 C CD1 . PHE A 1 441 ? -62.089 -12.650 13.256 1.00 151.93 ? 467 PHE A CD1 1 ATOM 3254 C CD2 . PHE A 1 441 ? -64.105 -13.044 14.441 1.00 96.58 ? 467 PHE A CD2 1 ATOM 3255 C CE1 . PHE A 1 441 ? -62.805 -12.138 12.187 1.00 131.45 ? 467 PHE A CE1 1 ATOM 3256 C CE2 . PHE A 1 441 ? -64.823 -12.536 13.390 1.00 99.67 ? 467 PHE A CE2 1 ATOM 3257 C CZ . PHE A 1 441 ? -64.175 -12.080 12.262 1.00 120.85 ? 467 PHE A CZ 1 ATOM 3258 N N . TYR A 1 442 ? -60.340 -15.658 17.517 1.00 154.22 ? 468 TYR A N 1 ATOM 3259 C CA . TYR A 1 442 ? -59.390 -15.757 18.621 1.00 143.22 ? 468 TYR A CA 1 ATOM 3260 C C . TYR A 1 442 ? -59.338 -14.574 19.580 1.00 148.03 ? 468 TYR A C 1 ATOM 3261 O O . TYR A 1 442 ? -58.363 -14.457 20.307 1.00 154.15 ? 468 TYR A O 1 ATOM 3262 C CB . TYR A 1 442 ? -57.975 -15.993 18.107 1.00 140.27 ? 468 TYR A CB 1 ATOM 3263 C CG . TYR A 1 442 ? -57.532 -17.427 17.969 1.00 123.86 ? 468 TYR A CG 1 ATOM 3264 C CD1 . TYR A 1 442 ? -57.658 -18.324 18.994 1.00 127.87 ? 468 TYR A CD1 1 ATOM 3265 C CD2 . TYR A 1 442 ? -56.948 -17.866 16.804 1.00 129.24 ? 468 TYR A CD2 1 ATOM 3266 C CE1 . TYR A 1 442 ? -57.215 -19.627 18.850 1.00 130.32 ? 468 TYR A CE1 1 ATOM 3267 C CE2 . TYR A 1 442 ? -56.511 -19.161 16.653 1.00 117.04 ? 468 TYR A CE2 1 ATOM 3268 C CZ . TYR A 1 442 ? -56.643 -20.039 17.675 1.00 108.08 ? 468 TYR A CZ 1 ATOM 3269 O OH . TYR A 1 442 ? -56.200 -21.320 17.505 1.00 89.58 ? 468 TYR A OH 1 ATOM 3270 N N . HIS A 1 443 ? -60.297 -13.662 19.551 1.00 137.10 ? 469 HIS A N 1 ATOM 3271 C CA . HIS A 1 443 ? -60.225 -12.626 20.553 1.00 150.66 ? 469 HIS A CA 1 ATOM 3272 C C . HIS A 1 443 ? -61.511 -12.202 21.177 1.00 157.94 ? 469 HIS A C 1 ATOM 3273 O O . HIS A 1 443 ? -61.926 -11.035 21.015 1.00 173.90 ? 469 HIS A O 1 ATOM 3274 C CB . HIS A 1 443 ? -59.430 -11.415 20.058 1.00 155.13 ? 469 HIS A CB 1 ATOM 3275 C CG . HIS A 1 443 ? -58.683 -10.674 21.157 1.00 136.12 ? 469 HIS A CG 1 ATOM 3276 N ND1 . HIS A 1 443 ? -59.176 -9.588 21.757 1.00 116.40 ? 469 HIS A ND1 1 ATOM 3277 C CD2 . HIS A 1 443 ? -57.442 -10.910 21.738 1.00 114.33 ? 469 HIS A CD2 1 ATOM 3278 C CE1 . HIS A 1 443 ? -58.304 -9.158 22.677 1.00 108.50 ? 469 HIS A CE1 1 ATOM 3279 N NE2 . HIS A 1 443 ? -57.245 -9.966 22.659 1.00 93.41 ? 469 HIS A NE2 1 ATOM 3280 N N . PHE A 1 444 ? -62.141 -13.108 21.918 1.00 156.85 ? 470 PHE A N 1 ATOM 3281 C CA . PHE A 1 444 ? -63.108 -12.725 22.925 1.00 148.03 ? 470 PHE A CA 1 ATOM 3282 C C . PHE A 1 444 ? -64.127 -11.735 22.402 1.00 164.29 ? 470 PHE A C 1 ATOM 3283 O O . PHE A 1 444 ? -64.292 -10.657 22.976 1.00 185.06 ? 470 PHE A O 1 ATOM 3284 C CB . PHE A 1 444 ? -62.382 -12.173 24.145 1.00 138.70 ? 470 PHE A CB 1 ATOM 3285 C CG . PHE A 1 444 ? -61.301 -13.076 24.655 1.00 130.95 ? 470 PHE A CG 1 ATOM 3286 C CD1 . PHE A 1 444 ? -61.299 -14.416 24.343 1.00 133.11 ? 470 PHE A CD1 1 ATOM 3287 C CD2 . PHE A 1 444 ? -60.289 -12.585 25.438 1.00 137.29 ? 470 PHE A CD2 1 ATOM 3288 C CE1 . PHE A 1 444 ? -60.311 -15.252 24.806 1.00 122.88 ? 470 PHE A CE1 1 ATOM 3289 C CE2 . PHE A 1 444 ? -59.292 -13.411 25.907 1.00 139.70 ? 470 PHE A CE2 1 ATOM 3290 C CZ . PHE A 1 444 ? -59.303 -14.750 25.590 1.00 127.37 ? 470 PHE A CZ 1 ATOM 3291 N N . THR A 1 445 ? -64.830 -12.114 21.340 1.00 161.90 ? 471 THR A N 1 ATOM 3292 C CA . THR A 1 445 ? -65.386 -11.229 20.322 1.00 153.50 ? 471 THR A CA 1 ATOM 3293 C C . THR A 1 445 ? -66.329 -10.222 20.964 1.00 143.49 ? 471 THR A C 1 ATOM 3294 O O . THR A 1 445 ? -66.654 -9.181 20.396 1.00 95.18 ? 471 THR A O 1 ATOM 3295 C CB . THR A 1 445 ? -66.117 -12.035 19.226 1.00 135.75 ? 471 THR A CB 1 ATOM 3296 O OG1 . THR A 1 445 ? -66.296 -11.223 18.065 1.00 125.30 ? 471 THR A OG1 1 ATOM 3297 C CG2 . THR A 1 445 ? -67.473 -12.513 19.707 1.00 127.56 ? 471 THR A CG2 1 ATOM 3298 N N . ARG A 1 446 ? -66.725 -10.543 22.183 1.00 130.88 ? 472 ARG A N 1 ATOM 3299 C CA . ARG A 1 446 ? -67.526 -9.674 23.000 1.00 116.89 ? 472 ARG A CA 1 ATOM 3300 C C . ARG A 1 446 ? -66.757 -8.391 23.107 1.00 99.81 ? 472 ARG A C 1 ATOM 3301 O O . ARG A 1 446 ? -65.537 -8.406 23.066 1.00 100.28 ? 472 ARG A O 1 ATOM 3302 C CB . ARG A 1 446 ? -67.633 -10.281 24.387 1.00 116.20 ? 472 ARG A CB 1 ATOM 3303 C CG . ARG A 1 446 ? -66.293 -10.730 24.940 1.00 125.17 ? 472 ARG A CG 1 ATOM 3304 C CD . ARG A 1 446 ? -66.475 -11.788 26.015 1.00 134.94 ? 472 ARG A CD 1 ATOM 3305 N NE . ARG A 1 446 ? -65.225 -12.171 26.665 1.00 134.80 ? 472 ARG A NE 1 ATOM 3306 C CZ . ARG A 1 446 ? -65.160 -12.779 27.844 1.00 135.10 ? 472 ARG A CZ 1 ATOM 3307 N NH1 . ARG A 1 446 ? -63.987 -13.101 28.367 1.00 132.01 ? 472 ARG A NH1 1 ATOM 3308 N NH2 . ARG A 1 446 ? -66.273 -13.067 28.503 1.00 133.71 ? 472 ARG A NH2 1 ATOM 3309 N N . PRO A 1 447 ? -67.538 -7.230 23.173 1.00 82.14 ? 473 PRO A N 1 ATOM 3310 C CA . PRO A 1 447 ? -66.756 -5.999 23.119 1.00 61.44 ? 473 PRO A CA 1 ATOM 3311 C C . PRO A 1 447 ? -65.941 -5.818 24.352 1.00 55.86 ? 473 PRO A C 1 ATOM 3312 O O . PRO A 1 447 ? -66.293 -6.325 25.382 1.00 62.27 ? 473 PRO A O 1 ATOM 3313 C CB . PRO A 1 447 ? -67.809 -4.910 23.083 1.00 61.20 ? 473 PRO A CB 1 ATOM 3314 C CG . PRO A 1 447 ? -68.999 -5.534 22.522 1.00 72.17 ? 473 PRO A CG 1 ATOM 3315 C CD . PRO A 1 447 ? -69.004 -6.779 23.301 1.00 75.28 ? 473 PRO A CD 1 ATOM 3316 N N . LEU A 1 448 ? -64.861 -5.075 24.229 1.00 45.23 ? 474 LEU A N 1 ATOM 3317 C CA . LEU A 1 448 ? -63.987 -4.799 25.328 1.00 48.60 ? 474 LEU A CA 1 ATOM 3318 C C . LEU A 1 448 ? -64.702 -4.046 26.413 1.00 51.78 ? 474 LEU A C 1 ATOM 3319 O O . LEU A 1 448 ? -64.500 -4.305 27.566 1.00 63.71 ? 474 LEU A O 1 ATOM 3320 C CB . LEU A 1 448 ? -62.797 -3.998 24.853 1.00 52.69 ? 474 LEU A CB 1 ATOM 3321 C CG . LEU A 1 448 ? -61.883 -4.650 23.838 1.00 51.90 ? 474 LEU A CG 1 ATOM 3322 C CD1 . LEU A 1 448 ? -60.724 -3.759 23.489 1.00 51.56 ? 474 LEU A CD1 1 ATOM 3323 C CD2 . LEU A 1 448 ? -61.393 -5.985 24.322 1.00 55.43 ? 474 LEU A CD2 1 ATOM 3324 N N . ILE A 1 449 ? -65.546 -3.110 26.042 1.00 47.66 ? 475 ILE A N 1 ATOM 3325 C CA . ILE A 1 449 ? -66.290 -2.287 27.010 1.00 46.78 ? 475 ILE A CA 1 ATOM 3326 C C . ILE A 1 449 ? -67.794 -2.382 26.738 1.00 44.02 ? 475 ILE A C 1 ATOM 3327 O O . ILE A 1 449 ? -68.203 -2.379 25.612 1.00 50.69 ? 475 ILE A O 1 ATOM 3328 C CB . ILE A 1 449 ? -65.961 -0.798 26.807 1.00 53.62 ? 475 ILE A CB 1 ATOM 3329 C CG1 . ILE A 1 449 ? -64.460 -0.563 26.690 1.00 60.01 ? 475 ILE A CG1 1 ATOM 3330 C CG2 . ILE A 1 449 ? -66.594 0.053 27.875 1.00 60.52 ? 475 ILE A CG2 1 ATOM 3331 C CD1 . ILE A 1 449 ? -63.664 -1.031 27.851 1.00 62.30 ? 475 ILE A CD1 1 ATOM 3332 N N . LYS A 1 450 ? -68.651 -2.405 27.746 1.00 51.79 ? 476 LYS A N 1 ATOM 3333 C CA . LYS A 1 450 ? -70.047 -2.445 27.401 1.00 48.45 ? 476 LYS A CA 1 ATOM 3334 C C . LYS A 1 450 ? -70.316 -1.276 26.442 1.00 51.18 ? 476 LYS A C 1 ATOM 3335 O O . LYS A 1 450 ? -69.761 -0.185 26.605 1.00 52.04 ? 476 LYS A O 1 ATOM 3336 C CB . LYS A 1 450 ? -70.939 -2.322 28.609 1.00 53.25 ? 476 LYS A CB 1 ATOM 3337 C CG . LYS A 1 450 ? -70.934 -3.540 29.506 1.00 73.15 ? 476 LYS A CG 1 ATOM 3338 C CD . LYS A 1 450 ? -71.956 -3.420 30.643 1.00 94.18 ? 476 LYS A CD 1 ATOM 3339 C CE . LYS A 1 450 ? -73.392 -3.239 30.125 1.00 100.30 ? 476 LYS A CE 1 ATOM 3340 N NZ . LYS A 1 450 ? -74.442 -3.153 31.189 1.00 92.25 ? 476 LYS A NZ 1 ATOM 3341 N N . PRO A 1 451 ? -71.126 -1.509 25.405 1.00 53.83 ? 477 PRO A N 1 ATOM 3342 C CA . PRO A 1 451 ? -71.480 -0.455 24.434 1.00 54.27 ? 477 PRO A CA 1 ATOM 3343 C C . PRO A 1 451 ? -72.292 0.700 25.044 1.00 48.71 ? 477 PRO A C 1 ATOM 3344 O O . PRO A 1 451 ? -72.178 1.840 24.621 1.00 45.46 ? 477 PRO A O 1 ATOM 3345 C CB . PRO A 1 451 ? -72.314 -1.214 23.415 1.00 56.22 ? 477 PRO A CB 1 ATOM 3346 C CG . PRO A 1 451 ? -71.680 -2.556 23.413 1.00 57.93 ? 477 PRO A CG 1 ATOM 3347 C CD . PRO A 1 451 ? -71.354 -2.844 24.851 1.00 54.96 ? 477 PRO A CD 1 ATOM 3348 N N . GLN A 1 452 ? -73.068 0.419 26.070 1.00 41.21 ? 478 GLN A N 1 ATOM 3349 C CA . GLN A 1 452 ? -73.811 1.461 26.673 1.00 44.22 ? 478 GLN A CA 1 ATOM 3350 C C . GLN A 1 452 ? -72.863 2.449 27.320 1.00 53.21 ? 478 GLN A C 1 ATOM 3351 O O . GLN A 1 452 ? -73.247 3.586 27.634 1.00 58.99 ? 478 GLN A O 1 ATOM 3352 C CB . GLN A 1 452 ? -74.775 0.932 27.729 1.00 51.01 ? 478 GLN A CB 1 ATOM 3353 C CG . GLN A 1 452 ? -75.860 -0.047 27.256 1.00 45.98 ? 478 GLN A CG 1 ATOM 3354 C CD . GLN A 1 452 ? -75.399 -1.482 27.088 1.00 51.07 ? 478 GLN A CD 1 ATOM 3355 O OE1 . GLN A 1 452 ? -74.215 -1.794 26.827 1.00 52.67 ? 478 GLN A OE1 1 ATOM 3356 N NE2 . GLN A 1 452 ? -76.343 -2.377 27.256 1.00 53.54 ? 478 GLN A NE2 1 ATOM 3357 N N . CYS A 1 453 ? -71.612 2.039 27.491 1.00 53.47 ? 479 CYS A N 1 ATOM 3358 C CA . CYS A 1 453 ? -70.641 2.897 28.124 1.00 51.51 ? 479 CYS A CA 1 ATOM 3359 C C . CYS A 1 453 ? -69.813 3.609 27.087 1.00 41.99 ? 479 CYS A C 1 ATOM 3360 O O . CYS A 1 453 ? -69.571 4.802 27.195 1.00 48.85 ? 479 CYS A O 1 ATOM 3361 C CB . CYS A 1 453 ? -69.722 2.084 29.082 1.00 53.62 ? 479 CYS A CB 1 ATOM 3362 S SG . CYS A 1 453 ? -68.732 3.087 30.254 1.00 56.20 ? 479 CYS A SG 1 ATOM 3363 N N . ALA A 1 454 ? -69.349 2.901 26.086 1.00 47.35 ? 480 ALA A N 1 ATOM 3364 C CA . ALA A 1 454 ? -68.507 3.558 25.077 1.00 53.31 ? 480 ALA A CA 1 ATOM 3365 C C . ALA A 1 454 ? -69.303 4.596 24.301 1.00 53.85 ? 480 ALA A C 1 ATOM 3366 O O . ALA A 1 454 ? -68.809 5.675 23.999 1.00 64.31 ? 480 ALA A O 1 ATOM 3367 C CB . ALA A 1 454 ? -67.893 2.547 24.138 1.00 51.52 ? 480 ALA A CB 1 ATOM 3368 N N . ALA A 1 455 ? -70.559 4.288 24.048 1.00 46.70 ? 481 ALA A N 1 ATOM 3369 C CA . ALA A 1 455 ? -71.435 5.192 23.322 1.00 49.05 ? 481 ALA A CA 1 ATOM 3370 C C . ALA A 1 455 ? -71.259 6.660 23.769 1.00 52.12 ? 481 ALA A C 1 ATOM 3371 O O . ALA A 1 455 ? -71.442 7.557 22.996 1.00 61.71 ? 481 ALA A O 1 ATOM 3372 C CB . ALA A 1 455 ? -72.890 4.756 23.510 1.00 44.43 ? 481 ALA A CB 1 ATOM 3373 N N . TYR A 1 456 ? -70.920 6.906 25.017 1.00 49.23 ? 482 TYR A N 1 ATOM 3374 C CA . TYR A 1 456 ? -70.761 8.280 25.458 1.00 47.99 ? 482 TYR A CA 1 ATOM 3375 C C . TYR A 1 456 ? -69.440 8.954 25.079 1.00 43.03 ? 482 TYR A C 1 ATOM 3376 O O . TYR A 1 456 ? -69.266 10.121 25.323 1.00 48.55 ? 482 TYR A O 1 ATOM 3377 C CB . TYR A 1 456 ? -70.905 8.367 26.981 1.00 48.61 ? 482 TYR A CB 1 ATOM 3378 C CG . TYR A 1 456 ? -72.277 8.133 27.493 1.00 44.86 ? 482 TYR A CG 1 ATOM 3379 C CD1 . TYR A 1 456 ? -73.174 9.164 27.551 1.00 47.35 ? 482 TYR A CD1 1 ATOM 3380 C CD2 . TYR A 1 456 ? -72.642 6.928 28.037 1.00 46.89 ? 482 TYR A CD2 1 ATOM 3381 C CE1 . TYR A 1 456 ? -74.436 8.990 28.083 1.00 46.55 ? 482 TYR A CE1 1 ATOM 3382 C CE2 . TYR A 1 456 ? -73.905 6.731 28.552 1.00 40.19 ? 482 TYR A CE2 1 ATOM 3383 C CZ . TYR A 1 456 ? -74.795 7.773 28.578 1.00 44.00 ? 482 TYR A CZ 1 ATOM 3384 O OH . TYR A 1 456 ? -76.059 7.617 29.093 1.00 45.24 ? 482 TYR A OH 1 ATOM 3385 N N . GLY A 1 457 ? -68.452 8.222 24.639 1.00 43.32 ? 483 GLY A N 1 ATOM 3386 C CA . GLY A 1 457 ? -67.212 8.883 24.321 1.00 44.93 ? 483 GLY A CA 1 ATOM 3387 C C . GLY A 1 457 ? -65.976 8.067 24.604 1.00 49.34 ? 483 GLY A C 1 ATOM 3388 O O . GLY A 1 457 ? -66.016 6.842 24.577 1.00 50.73 ? 483 GLY A O 1 ATOM 3389 N N . LYS A 1 458 ? -64.866 8.758 24.864 1.00 47.21 ? 484 LYS A N 1 ATOM 3390 C CA . LYS A 1 458 ? -63.630 8.085 25.135 1.00 51.50 ? 484 LYS A CA 1 ATOM 3391 C C . LYS A 1 458 ? -63.843 7.243 26.383 1.00 49.52 ? 484 LYS A C 1 ATOM 3392 O O . LYS A 1 458 ? -64.350 7.728 27.396 1.00 52.68 ? 484 LYS A O 1 ATOM 3393 C CB . LYS A 1 458 ? -62.453 9.050 25.321 1.00 55.26 ? 484 LYS A CB 1 ATOM 3394 C CG . LYS A 1 458 ? -62.212 10.015 24.185 1.00 64.69 ? 484 LYS A CG 1 ATOM 3395 C CD . LYS A 1 458 ? -60.931 10.804 24.420 1.00 72.35 ? 484 LYS A CD 1 ATOM 3396 C CE . LYS A 1 458 ? -60.859 12.032 23.525 1.00 76.38 ? 484 LYS A CE 1 ATOM 3397 N NZ . LYS A 1 458 ? -61.017 11.732 22.081 1.00 88.50 ? 484 LYS A NZ 1 ATOM 3398 N N . ALA A 1 459 ? -63.379 6.004 26.304 1.00 45.23 ? 485 ALA A N 1 ATOM 3399 C CA . ALA A 1 459 ? -63.519 5.058 27.357 1.00 43.01 ? 485 ALA A CA 1 ATOM 3400 C C . ALA A 1 459 ? -62.215 4.603 27.873 1.00 43.17 ? 485 ALA A C 1 ATOM 3401 O O . ALA A 1 459 ? -61.311 4.227 27.098 1.00 42.61 ? 485 ALA A O 1 ATOM 3402 C CB . ALA A 1 459 ? -64.269 3.858 26.830 1.00 42.69 ? 485 ALA A CB 1 ATOM 3403 N N . LEU A 1 460 ? -62.140 4.518 29.193 1.00 39.29 ? 486 LEU A N 1 ATOM 3404 C CA . LEU A 1 460 ? -60.928 4.029 29.838 1.00 44.39 ? 486 LEU A CA 1 ATOM 3405 C C . LEU A 1 460 ? -61.317 2.864 30.748 1.00 43.19 ? 486 LEU A C 1 ATOM 3406 O O . LEU A 1 460 ? -62.084 3.042 31.694 1.00 41.61 ? 486 LEU A O 1 ATOM 3407 C CB . LEU A 1 460 ? -60.278 5.126 30.692 1.00 44.61 ? 486 LEU A CB 1 ATOM 3408 C CG . LEU A 1 460 ? -59.081 4.694 31.542 1.00 44.70 ? 486 LEU A CG 1 ATOM 3409 C CD1 . LEU A 1 460 ? -57.973 4.117 30.685 1.00 49.20 ? 486 LEU A CD1 1 ATOM 3410 C CD2 . LEU A 1 460 ? -58.558 5.876 32.327 1.00 48.62 ? 486 LEU A CD2 1 ATOM 3411 N N . ASP A 1 461 ? -60.720 1.706 30.527 1.00 42.03 ? 487 ASP A N 1 ATOM 3412 C CA . ASP A 1 461 ? -61.017 0.562 31.365 1.00 39.74 ? 487 ASP A CA 1 ATOM 3413 C C . ASP A 1 461 ? -59.840 0.239 32.261 1.00 39.79 ? 487 ASP A C 1 ATOM 3414 O O . ASP A 1 461 ? -58.764 -0.187 31.785 1.00 41.18 ? 487 ASP A O 1 ATOM 3415 C CB . ASP A 1 461 ? -61.365 -0.650 30.533 1.00 43.58 ? 487 ASP A CB 1 ATOM 3416 C CG . ASP A 1 461 ? -61.991 -1.755 31.357 1.00 53.34 ? 487 ASP A CG 1 ATOM 3417 O OD1 . ASP A 1 461 ? -61.583 -1.970 32.524 1.00 60.83 ? 487 ASP A OD1 1 ATOM 3418 O OD2 . ASP A 1 461 ? -62.896 -2.412 30.820 1.00 55.01 ? 487 ASP A OD2 1 ATOM 3419 N N . LEU A 1 462 ? -60.064 0.421 33.563 1.00 34.72 ? 488 LEU A N 1 ATOM 3420 C CA . LEU A 1 462 ? -59.045 0.152 34.580 1.00 46.90 ? 488 LEU A CA 1 ATOM 3421 C C . LEU A 1 462 ? -59.520 -0.904 35.600 1.00 46.56 ? 488 LEU A C 1 ATOM 3422 O O . LEU A 1 462 ? -59.074 -0.958 36.743 1.00 52.08 ? 488 LEU A O 1 ATOM 3423 C CB . LEU A 1 462 ? -58.625 1.449 35.266 1.00 44.59 ? 488 LEU A CB 1 ATOM 3424 C CG . LEU A 1 462 ? -57.675 2.341 34.487 1.00 43.67 ? 488 LEU A CG 1 ATOM 3425 C CD1 . LEU A 1 462 ? -57.503 3.682 35.148 1.00 47.27 ? 488 LEU A CD1 1 ATOM 3426 C CD2 . LEU A 1 462 ? -56.336 1.648 34.388 1.00 47.61 ? 488 LEU A CD2 1 ATOM 3427 N N . SER A 1 463 ? -60.392 -1.781 35.148 1.00 41.57 ? 489 SER A N 1 ATOM 3428 C CA . SER A 1 463 ? -60.899 -2.821 36.003 1.00 39.25 ? 489 SER A CA 1 ATOM 3429 C C . SER A 1 463 ? -59.773 -3.813 36.279 1.00 40.26 ? 489 SER A C 1 ATOM 3430 O O . SER A 1 463 ? -58.820 -3.901 35.518 1.00 37.82 ? 489 SER A O 1 ATOM 3431 C CB . SER A 1 463 ? -62.037 -3.561 35.312 1.00 35.36 ? 489 SER A CB 1 ATOM 3432 O OG . SER A 1 463 ? -61.551 -4.279 34.159 1.00 39.91 ? 489 SER A OG 1 ATOM 3433 N N . LEU A 1 464 ? -59.839 -4.502 37.406 1.00 39.17 ? 490 LEU A N 1 ATOM 3434 C CA . LEU A 1 464 ? -58.832 -5.537 37.703 1.00 41.28 ? 490 LEU A CA 1 ATOM 3435 C C . LEU A 1 464 ? -57.424 -5.042 37.806 1.00 36.86 ? 490 LEU A C 1 ATOM 3436 O O . LEU A 1 464 ? -56.522 -5.613 37.261 1.00 38.35 ? 490 LEU A O 1 ATOM 3437 C CB . LEU A 1 464 ? -58.932 -6.715 36.710 1.00 41.49 ? 490 LEU A CB 1 ATOM 3438 C CG . LEU A 1 464 ? -60.320 -7.430 36.803 1.00 50.36 ? 490 LEU A CG 1 ATOM 3439 C CD1 . LEU A 1 464 ? -60.626 -8.364 35.652 1.00 54.05 ? 490 LEU A CD1 1 ATOM 3440 C CD2 . LEU A 1 464 ? -60.458 -8.198 38.103 1.00 50.89 ? 490 LEU A CD2 1 ATOM 3441 N N . ASN A 1 465 ? -57.281 -3.879 38.398 1.00 40.23 ? 491 ASN A N 1 ATOM 3442 C CA . ASN A 1 465 ? -55.989 -3.332 38.668 1.00 43.17 ? 491 ASN A CA 1 ATOM 3443 C C . ASN A 1 465 ? -55.907 -3.269 40.201 1.00 45.63 ? 491 ASN A C 1 ATOM 3444 O O . ASN A 1 465 ? -56.715 -3.913 40.886 1.00 45.56 ? 491 ASN A O 1 ATOM 3445 C CB . ASN A 1 465 ? -55.752 -1.962 37.982 1.00 47.88 ? 491 ASN A CB 1 ATOM 3446 C CG . ASN A 1 465 ? -55.374 -2.094 36.521 1.00 42.56 ? 491 ASN A CG 1 ATOM 3447 O OD1 . ASN A 1 465 ? -54.183 -2.054 36.206 1.00 47.23 ? 491 ASN A OD1 1 ATOM 3448 N ND2 . ASN A 1 465 ? -56.327 -2.483 35.678 1.00 43.34 ? 491 ASN A ND2 1 ATOM 3449 N N . SER A 1 466 ? -54.991 -2.472 40.743 1.00 43.20 ? 492 SER A N 1 ATOM 3450 C CA . SER A 1 466 ? -54.839 -2.382 42.188 1.00 44.55 ? 492 SER A CA 1 ATOM 3451 C C . SER A 1 466 ? -55.142 -1.008 42.686 1.00 42.15 ? 492 SER A C 1 ATOM 3452 O O . SER A 1 466 ? -54.485 -0.512 43.572 1.00 39.87 ? 492 SER A O 1 ATOM 3453 C CB . SER A 1 466 ? -53.421 -2.727 42.536 1.00 40.61 ? 492 SER A CB 1 ATOM 3454 O OG . SER A 1 466 ? -53.146 -4.035 42.117 1.00 54.95 ? 492 SER A OG 1 ATOM 3455 N N . ILE A 1 467 ? -56.145 -0.377 42.118 1.00 44.65 ? 493 ILE A N 1 ATOM 3456 C CA . ILE A 1 467 ? -56.459 0.973 42.534 1.00 45.35 ? 493 ILE A CA 1 ATOM 3457 C C . ILE A 1 467 ? -57.350 0.841 43.745 1.00 42.53 ? 493 ILE A C 1 ATOM 3458 O O . ILE A 1 467 ? -58.552 1.131 43.709 1.00 48.72 ? 493 ILE A O 1 ATOM 3459 C CB . ILE A 1 467 ? -57.042 1.771 41.348 1.00 40.60 ? 493 ILE A CB 1 ATOM 3460 C CG1 . ILE A 1 467 ? -56.040 1.704 40.180 1.00 49.40 ? 493 ILE A CG1 1 ATOM 3461 C CG2 . ILE A 1 467 ? -57.231 3.213 41.726 1.00 39.54 ? 493 ILE A CG2 1 ATOM 3462 C CD1 . ILE A 1 467 ? -56.561 2.263 38.860 1.00 54.79 ? 493 ILE A CD1 1 ATOM 3463 N N . PHE A 1 468 ? -56.764 0.398 44.831 1.00 46.61 ? 494 PHE A N 1 ATOM 3464 C CA . PHE A 1 468 ? -57.524 0.158 46.035 1.00 48.37 ? 494 PHE A CA 1 ATOM 3465 C C . PHE A 1 468 ? -57.935 1.423 46.708 1.00 46.69 ? 494 PHE A C 1 ATOM 3466 O O . PHE A 1 468 ? -58.732 1.441 47.606 1.00 46.38 ? 494 PHE A O 1 ATOM 3467 C CB . PHE A 1 468 ? -56.820 -0.800 46.979 1.00 43.65 ? 494 PHE A CB 1 ATOM 3468 C CG . PHE A 1 468 ? -55.546 -0.301 47.527 1.00 40.51 ? 494 PHE A CG 1 ATOM 3469 C CD1 . PHE A 1 468 ? -55.527 0.389 48.682 1.00 46.62 ? 494 PHE A CD1 1 ATOM 3470 C CD2 . PHE A 1 468 ? -54.376 -0.582 46.921 1.00 43.38 ? 494 PHE A CD2 1 ATOM 3471 C CE1 . PHE A 1 468 ? -54.361 0.841 49.209 1.00 45.41 ? 494 PHE A CE1 1 ATOM 3472 C CE2 . PHE A 1 468 ? -53.200 -0.136 47.440 1.00 41.33 ? 494 PHE A CE2 1 ATOM 3473 C CZ . PHE A 1 468 ? -53.192 0.577 48.586 1.00 45.96 ? 494 PHE A CZ 1 ATOM 3474 N N . PHE A 1 469 ? -57.319 2.489 46.273 1.00 45.88 ? 495 PHE A N 1 ATOM 3475 C CA . PHE A 1 469 ? -57.623 3.784 46.758 1.00 53.56 ? 495 PHE A CA 1 ATOM 3476 C C . PHE A 1 469 ? -57.305 4.705 45.610 1.00 50.52 ? 495 PHE A C 1 ATOM 3477 O O . PHE A 1 469 ? -56.306 4.542 44.971 1.00 43.60 ? 495 PHE A O 1 ATOM 3478 C CB . PHE A 1 469 ? -56.713 3.979 47.949 1.00 57.11 ? 495 PHE A CB 1 ATOM 3479 C CG . PHE A 1 469 ? -56.425 5.375 48.290 1.00 52.37 ? 495 PHE A CG 1 ATOM 3480 C CD1 . PHE A 1 469 ? -57.407 6.191 48.755 1.00 72.62 ? 495 PHE A CD1 1 ATOM 3481 C CD2 . PHE A 1 469 ? -55.158 5.843 48.200 1.00 54.70 ? 495 PHE A CD2 1 ATOM 3482 C CE1 . PHE A 1 469 ? -57.139 7.481 49.111 1.00 74.69 ? 495 PHE A CE1 1 ATOM 3483 C CE2 . PHE A 1 469 ? -54.869 7.126 48.532 1.00 64.96 ? 495 PHE A CE2 1 ATOM 3484 C CZ . PHE A 1 469 ? -55.862 7.953 48.990 1.00 79.48 ? 495 PHE A CZ 1 ATOM 3485 N N . ILE A 1 470 ? -58.138 5.697 45.371 1.00 49.84 ? 496 ILE A N 1 ATOM 3486 C CA . ILE A 1 470 ? -57.895 6.621 44.297 1.00 51.00 ? 496 ILE A CA 1 ATOM 3487 C C . ILE A 1 470 ? -57.213 7.794 44.920 1.00 54.35 ? 496 ILE A C 1 ATOM 3488 O O . ILE A 1 470 ? -57.766 8.462 45.754 1.00 46.01 ? 496 ILE A O 1 ATOM 3489 C CB . ILE A 1 470 ? -59.198 7.089 43.648 1.00 52.68 ? 496 ILE A CB 1 ATOM 3490 C CG1 . ILE A 1 470 ? -59.811 5.990 42.818 1.00 54.70 ? 496 ILE A CG1 1 ATOM 3491 C CG2 . ILE A 1 470 ? -58.973 8.256 42.723 1.00 51.49 ? 496 ILE A CG2 1 ATOM 3492 C CD1 . ILE A 1 470 ? -61.274 6.198 42.567 1.00 49.19 ? 496 ILE A CD1 1 ATOM 3493 N N . GLY A 1 471 ? -55.996 8.035 44.476 1.00 55.60 ? 497 GLY A N 1 ATOM 3494 C CA . GLY A 1 471 ? -55.165 9.132 44.993 1.00 61.28 ? 497 GLY A CA 1 ATOM 3495 C C . GLY A 1 471 ? -55.518 10.493 44.407 1.00 66.18 ? 497 GLY A C 1 ATOM 3496 O O . GLY A 1 471 ? -56.280 10.589 43.460 1.00 63.54 ? 497 GLY A O 1 ATOM 3497 N N . PRO A 1 472 ? -54.901 11.561 44.923 1.00 85.26 ? 498 PRO A N 1 ATOM 3498 C CA . PRO A 1 472 ? -55.212 12.908 44.409 1.00 74.92 ? 498 PRO A CA 1 ATOM 3499 C C . PRO A 1 472 ? -54.754 13.172 42.954 1.00 60.55 ? 498 PRO A C 1 ATOM 3500 O O . PRO A 1 472 ? -55.355 13.963 42.272 1.00 61.53 ? 498 PRO A O 1 ATOM 3501 C CB . PRO A 1 472 ? -54.498 13.836 45.401 1.00 82.39 ? 498 PRO A CB 1 ATOM 3502 C CG . PRO A 1 472 ? -54.024 12.962 46.530 1.00 80.67 ? 498 PRO A CG 1 ATOM 3503 C CD . PRO A 1 472 ? -53.858 11.594 45.961 1.00 78.57 ? 498 PRO A CD 1 ATOM 3504 N N . ASN A 1 473 ? -53.724 12.486 42.489 1.00 62.56 ? 499 ASN A N 1 ATOM 3505 C CA . ASN A 1 473 ? -53.235 12.649 41.120 1.00 61.28 ? 499 ASN A CA 1 ATOM 3506 C C . ASN A 1 473 ? -53.484 11.372 40.313 1.00 63.06 ? 499 ASN A C 1 ATOM 3507 O O . ASN A 1 473 ? -52.824 11.094 39.323 1.00 53.35 ? 499 ASN A O 1 ATOM 3508 C CB . ASN A 1 473 ? -51.727 12.900 41.170 1.00 77.58 ? 499 ASN A CB 1 ATOM 3509 C CG . ASN A 1 473 ? -51.373 14.140 41.961 1.00 90.42 ? 499 ASN A CG 1 ATOM 3510 O OD1 . ASN A 1 473 ? -52.048 15.178 41.859 1.00 85.29 ? 499 ASN A OD1 1 ATOM 3511 N ND2 . ASN A 1 473 ? -50.275 14.064 42.711 1.00 94.45 ? 499 ASN A ND2 1 ATOM 3512 N N . GLN A 1 474 ? -54.452 10.587 40.729 1.00 66.06 ? 500 GLN A N 1 ATOM 3513 C CA . GLN A 1 474 ? -54.678 9.348 40.052 1.00 60.24 ? 500 GLN A CA 1 ATOM 3514 C C . GLN A 1 474 ? -54.972 9.544 38.573 1.00 58.63 ? 500 GLN A C 1 ATOM 3515 O O . GLN A 1 474 ? -54.395 8.877 37.725 1.00 59.70 ? 500 GLN A O 1 ATOM 3516 C CB . GLN A 1 474 ? -55.863 8.604 40.686 1.00 64.64 ? 500 GLN A CB 1 ATOM 3517 C CG . GLN A 1 474 ? -55.911 7.144 40.279 1.00 56.61 ? 500 GLN A CG 1 ATOM 3518 C CD . GLN A 1 474 ? -54.759 6.401 40.911 1.00 55.22 ? 500 GLN A CD 1 ATOM 3519 O OE1 . GLN A 1 474 ? -54.521 6.545 42.110 1.00 55.72 ? 500 GLN A OE1 1 ATOM 3520 N NE2 . GLN A 1 474 ? -54.099 5.541 40.145 1.00 53.77 ? 500 GLN A NE2 1 ATOM 3521 N N . PHE A 1 475 ? -55.866 10.477 38.275 1.00 55.24 ? 501 PHE A N 1 ATOM 3522 C CA . PHE A 1 475 ? -56.283 10.704 36.912 1.00 59.78 ? 501 PHE A CA 1 ATOM 3523 C C . PHE A 1 475 ? -55.707 11.928 36.172 1.00 63.97 ? 501 PHE A C 1 ATOM 3524 O O . PHE A 1 475 ? -56.155 12.253 35.083 1.00 68.91 ? 501 PHE A O 1 ATOM 3525 C CB . PHE A 1 475 ? -57.799 10.728 36.902 1.00 55.48 ? 501 PHE A CB 1 ATOM 3526 C CG . PHE A 1 475 ? -58.400 9.552 37.580 1.00 52.10 ? 501 PHE A CG 1 ATOM 3527 C CD1 . PHE A 1 475 ? -58.160 8.285 37.114 1.00 57.76 ? 501 PHE A CD1 1 ATOM 3528 C CD2 . PHE A 1 475 ? -59.320 9.711 38.584 1.00 54.91 ? 501 PHE A CD2 1 ATOM 3529 C CE1 . PHE A 1 475 ? -58.724 7.181 37.730 1.00 55.61 ? 501 PHE A CE1 1 ATOM 3530 C CE2 . PHE A 1 475 ? -59.935 8.614 39.174 1.00 51.57 ? 501 PHE A CE2 1 ATOM 3531 C CZ . PHE A 1 475 ? -59.630 7.351 38.754 1.00 46.48 ? 501 PHE A CZ 1 ATOM 3532 N N . GLU A 1 476 ? -54.644 12.522 36.700 1.00 68.90 ? 502 GLU A N 1 ATOM 3533 C CA . GLU A 1 476 ? -54.026 13.687 36.071 1.00 76.50 ? 502 GLU A CA 1 ATOM 3534 C C . GLU A 1 476 ? -53.492 13.397 34.664 1.00 71.10 ? 502 GLU A C 1 ATOM 3535 O O . GLU A 1 476 ? -52.992 12.323 34.388 1.00 74.65 ? 502 GLU A O 1 ATOM 3536 C CB . GLU A 1 476 ? -52.893 14.234 36.954 1.00 80.12 ? 502 GLU A CB 1 ATOM 3537 C CG . GLU A 1 476 ? -53.347 14.646 38.359 1.00 100.88 ? 502 GLU A CG 1 ATOM 3538 C CD . GLU A 1 476 ? -54.453 15.722 38.398 1.00 111.86 ? 502 GLU A CD 1 ATOM 3539 O OE1 . GLU A 1 476 ? -54.687 16.412 37.373 1.00 125.77 ? 502 GLU A OE1 1 ATOM 3540 O OE2 . GLU A 1 476 ? -55.070 15.903 39.483 1.00 93.49 ? 502 GLU A OE2 1 ATOM 3541 N N . ASN A 1 477 ? -53.635 14.364 33.770 1.00 70.47 ? 503 ASN A N 1 ATOM 3542 C CA . ASN A 1 477 ? -53.146 14.231 32.385 1.00 69.55 ? 503 ASN A CA 1 ATOM 3543 C C . ASN A 1 477 ? -53.935 13.299 31.489 1.00 66.11 ? 503 ASN A C 1 ATOM 3544 O O . ASN A 1 477 ? -53.436 12.902 30.436 1.00 70.31 ? 503 ASN A O 1 ATOM 3545 C CB . ASN A 1 477 ? -51.672 13.810 32.371 1.00 72.24 ? 503 ASN A CB 1 ATOM 3546 C CG . ASN A 1 477 ? -50.789 14.775 33.126 1.00 67.74 ? 503 ASN A CG 1 ATOM 3547 O OD1 . ASN A 1 477 ? -51.106 15.949 33.237 1.00 67.74 ? 503 ASN A OD1 1 ATOM 3548 N ND2 . ASN A 1 477 ? -49.664 14.288 33.626 1.00 69.25 ? 503 ASN A ND2 1 ATOM 3549 N N . LEU A 1 478 ? -55.100 12.848 31.942 1.00 67.60 ? 504 LEU A N 1 ATOM 3550 C CA . LEU A 1 478 ? -55.934 11.977 31.103 1.00 63.57 ? 504 LEU A CA 1 ATOM 3551 C C . LEU A 1 478 ? -56.777 12.766 30.140 1.00 61.34 ? 504 LEU A C 1 ATOM 3552 O O . LEU A 1 478 ? -57.207 13.863 30.449 1.00 76.49 ? 504 LEU A O 1 ATOM 3553 C CB . LEU A 1 478 ? -56.902 11.164 31.938 1.00 61.71 ? 504 LEU A CB 1 ATOM 3554 C CG . LEU A 1 478 ? -56.370 9.963 32.690 1.00 65.80 ? 504 LEU A CG 1 ATOM 3555 C CD1 . LEU A 1 478 ? -57.487 9.403 33.555 1.00 53.11 ? 504 LEU A CD1 1 ATOM 3556 C CD2 . LEU A 1 478 ? -55.859 8.929 31.678 1.00 58.80 ? 504 LEU A CD2 1 ATOM 3557 N N . PRO A 1 479 ? -57.054 12.199 28.971 1.00 64.57 ? 505 PRO A N 1 ATOM 3558 C CA . PRO A 1 479 ? -57.934 12.964 28.083 1.00 57.72 ? 505 PRO A CA 1 ATOM 3559 C C . PRO A 1 479 ? -59.334 13.033 28.704 1.00 54.90 ? 505 PRO A C 1 ATOM 3560 O O . PRO A 1 479 ? -59.554 12.506 29.772 1.00 62.50 ? 505 PRO A O 1 ATOM 3561 C CB . PRO A 1 479 ? -57.921 12.180 26.786 1.00 55.09 ? 505 PRO A CB 1 ATOM 3562 C CG . PRO A 1 479 ? -57.262 10.857 27.111 1.00 64.17 ? 505 PRO A CG 1 ATOM 3563 C CD . PRO A 1 479 ? -56.371 11.101 28.280 1.00 64.13 ? 505 PRO A CD 1 ATOM 3564 N N . ASP A 1 480 ? -60.241 13.746 28.080 1.00 59.88 ? 506 ASP A N 1 ATOM 3565 C CA . ASP A 1 480 ? -61.568 13.900 28.610 1.00 60.09 ? 506 ASP A CA 1 ATOM 3566 C C . ASP A 1 480 ? -62.308 12.593 28.483 1.00 63.57 ? 506 ASP A C 1 ATOM 3567 O O . ASP A 1 480 ? -62.927 12.337 27.466 1.00 76.83 ? 506 ASP A O 1 ATOM 3568 C CB . ASP A 1 480 ? -62.293 14.986 27.827 1.00 61.38 ? 506 ASP A CB 1 ATOM 3569 C CG . ASP A 1 480 ? -63.668 15.287 28.374 1.00 71.25 ? 506 ASP A CG 1 ATOM 3570 O OD1 . ASP A 1 480 ? -63.956 14.924 29.534 1.00 88.39 ? 506 ASP A OD1 1 ATOM 3571 O OD2 . ASP A 1 480 ? -64.430 15.980 27.674 1.00 81.65 ? 506 ASP A OD2 1 ATOM 3572 N N . ILE A 1 481 ? -62.333 11.827 29.564 1.00 58.05 ? 507 ILE A N 1 ATOM 3573 C CA . ILE A 1 481 ? -62.986 10.520 29.593 1.00 50.68 ? 507 ILE A CA 1 ATOM 3574 C C . ILE A 1 481 ? -64.467 10.594 29.805 1.00 48.02 ? 507 ILE A C 1 ATOM 3575 O O . ILE A 1 481 ? -64.928 11.269 30.710 1.00 45.61 ? 507 ILE A O 1 ATOM 3576 C CB . ILE A 1 481 ? -62.385 9.666 30.723 1.00 53.38 ? 507 ILE A CB 1 ATOM 3577 C CG1 . ILE A 1 481 ? -60.938 9.360 30.413 1.00 49.45 ? 507 ILE A CG1 1 ATOM 3578 C CG2 . ILE A 1 481 ? -63.157 8.390 30.932 1.00 59.53 ? 507 ILE A CG2 1 ATOM 3579 C CD1 . ILE A 1 481 ? -60.747 8.739 29.059 1.00 48.73 ? 507 ILE A CD1 1 ATOM 3580 N N . ALA A 1 482 ? -65.217 9.852 28.999 1.00 44.44 ? 508 ALA A N 1 ATOM 3581 C CA . ALA A 1 482 ? -66.686 9.837 29.142 1.00 45.74 ? 508 ALA A CA 1 ATOM 3582 C C . ALA A 1 482 ? -67.176 8.596 29.865 1.00 49.58 ? 508 ALA A C 1 ATOM 3583 O O . ALA A 1 482 ? -68.223 8.626 30.564 1.00 49.20 ? 508 ALA A O 1 ATOM 3584 C CB . ALA A 1 482 ? -67.351 9.893 27.777 1.00 42.03 ? 508 ALA A CB 1 ATOM 3585 N N . CYS A 1 483 ? -66.410 7.519 29.681 1.00 40.79 ? 509 CYS A N 1 ATOM 3586 C CA . CYS A 1 483 ? -66.702 6.197 30.209 1.00 48.86 ? 509 CYS A CA 1 ATOM 3587 C C . CYS A 1 483 ? -65.504 5.667 30.970 1.00 43.47 ? 509 CYS A C 1 ATOM 3588 O O . CYS A 1 483 ? -64.417 5.479 30.392 1.00 45.42 ? 509 CYS A O 1 ATOM 3589 C CB . CYS A 1 483 ? -67.010 5.284 29.008 1.00 53.60 ? 509 CYS A CB 1 ATOM 3590 S SG . CYS A 1 483 ? -66.989 3.499 29.297 1.00 59.65 ? 509 CYS A SG 1 ATOM 3591 N N . LEU A 1 484 ? -65.746 5.259 32.209 1.00 43.53 ? 510 LEU A N 1 ATOM 3592 C CA . LEU A 1 484 ? -64.669 4.766 33.087 1.00 47.00 ? 510 LEU A CA 1 ATOM 3593 C C . LEU A 1 484 ? -65.075 3.522 33.901 1.00 44.83 ? 510 LEU A C 1 ATOM 3594 O O . LEU A 1 484 ? -66.072 3.535 34.644 1.00 38.69 ? 510 LEU A O 1 ATOM 3595 C CB . LEU A 1 484 ? -64.289 5.895 34.094 1.00 42.70 ? 510 LEU A CB 1 ATOM 3596 C CG . LEU A 1 484 ? -63.132 5.626 35.055 1.00 44.95 ? 510 LEU A CG 1 ATOM 3597 C CD1 . LEU A 1 484 ? -61.803 5.565 34.327 1.00 41.98 ? 510 LEU A CD1 1 ATOM 3598 C CD2 . LEU A 1 484 ? -63.072 6.704 36.106 1.00 51.79 ? 510 LEU A CD2 1 ATOM 3599 N N . ASN A 1 485 ? -64.241 2.502 33.856 1.00 41.52 ? 511 ASN A N 1 ATOM 3600 C CA . ASN A 1 485 ? -64.506 1.297 34.613 1.00 44.84 ? 511 ASN A CA 1 ATOM 3601 C C . ASN A 1 485 ? -63.409 1.124 35.703 1.00 43.97 ? 511 ASN A C 1 ATOM 3602 O O . ASN A 1 485 ? -62.199 1.025 35.387 1.00 38.83 ? 511 ASN A O 1 ATOM 3603 C CB . ASN A 1 485 ? -64.504 0.092 33.670 1.00 42.82 ? 511 ASN A CB 1 ATOM 3604 C CG . ASN A 1 485 ? -65.138 -1.152 34.288 1.00 47.75 ? 511 ASN A CG 1 ATOM 3605 O OD1 . ASN A 1 485 ? -65.470 -1.183 35.469 1.00 50.59 ? 511 ASN A OD1 1 ATOM 3606 N ND2 . ASN A 1 485 ? -65.337 -2.166 33.462 1.00 49.25 ? 511 ASN A ND2 1 ATOM 3607 N N . LEU A 1 486 ? -63.835 1.098 36.964 1.00 38.40 ? 512 LEU A N 1 ATOM 3608 C CA . LEU A 1 486 ? -62.920 0.910 38.115 1.00 39.35 ? 512 LEU A CA 1 ATOM 3609 C C . LEU A 1 486 ? -63.342 -0.312 38.947 1.00 40.11 ? 512 LEU A C 1 ATOM 3610 O O . LEU A 1 486 ? -63.072 -0.414 40.139 1.00 35.97 ? 512 LEU A O 1 ATOM 3611 C CB . LEU A 1 486 ? -62.935 2.128 38.985 1.00 38.05 ? 512 LEU A CB 1 ATOM 3612 C CG . LEU A 1 486 ? -62.306 3.363 38.374 1.00 43.25 ? 512 LEU A CG 1 ATOM 3613 C CD1 . LEU A 1 486 ? -62.606 4.535 39.278 1.00 43.61 ? 512 LEU A CD1 1 ATOM 3614 C CD2 . LEU A 1 486 ? -60.817 3.147 38.210 1.00 42.26 ? 512 LEU A CD2 1 ATOM 3615 N N . SER A 1 487 ? -64.013 -1.233 38.288 1.00 41.00 ? 513 SER A N 1 ATOM 3616 C CA . SER A 1 487 ? -64.489 -2.426 38.916 1.00 43.44 ? 513 SER A CA 1 ATOM 3617 C C . SER A 1 487 ? -63.345 -3.329 39.366 1.00 44.65 ? 513 SER A C 1 ATOM 3618 O O . SER A 1 487 ? -62.271 -3.328 38.787 1.00 42.12 ? 513 SER A O 1 ATOM 3619 C CB . SER A 1 487 ? -65.377 -3.179 37.906 1.00 43.71 ? 513 SER A CB 1 ATOM 3620 O OG . SER A 1 487 ? -65.984 -4.336 38.441 1.00 42.51 ? 513 SER A OG 1 ATOM 3621 N N . ALA A 1 488 ? -63.564 -4.038 40.468 1.00 41.65 ? 514 ALA A N 1 ATOM 3622 C CA . ALA A 1 488 ? -62.591 -4.997 40.969 1.00 33.98 ? 514 ALA A CA 1 ATOM 3623 C C . ALA A 1 488 ? -61.206 -4.504 41.215 1.00 35.38 ? 514 ALA A C 1 ATOM 3624 O O . ALA A 1 488 ? -60.256 -5.091 40.709 1.00 39.51 ? 514 ALA A O 1 ATOM 3625 C CB . ALA A 1 488 ? -62.523 -6.201 40.053 1.00 35.09 ? 514 ALA A CB 1 ATOM 3626 N N . ASN A 1 489 ? -61.087 -3.496 42.069 1.00 39.34 ? 515 ASN A N 1 ATOM 3627 C CA . ASN A 1 489 ? -59.813 -2.935 42.462 1.00 44.59 ? 515 ASN A CA 1 ATOM 3628 C C . ASN A 1 489 ? -59.622 -2.931 43.989 1.00 43.00 ? 515 ASN A C 1 ATOM 3629 O O . ASN A 1 489 ? -58.740 -2.281 44.477 1.00 53.89 ? 515 ASN A O 1 ATOM 3630 C CB . ASN A 1 489 ? -59.737 -1.494 41.930 1.00 49.70 ? 515 ASN A CB 1 ATOM 3631 C CG . ASN A 1 489 ? -59.318 -1.430 40.492 1.00 47.38 ? 515 ASN A CG 1 ATOM 3632 O OD1 . ASN A 1 489 ? -58.120 -1.577 40.182 1.00 46.19 ? 515 ASN A OD1 1 ATOM 3633 N ND2 . ASN A 1 489 ? -60.251 -1.043 39.622 1.00 44.01 ? 515 ASN A ND2 1 ATOM 3634 N N . SER A 1 490 ? -60.407 -3.697 44.727 1.00 46.44 ? 516 SER A N 1 ATOM 3635 C CA . SER A 1 490 ? -60.318 -3.725 46.214 1.00 45.04 ? 516 SER A CA 1 ATOM 3636 C C . SER A 1 490 ? -60.322 -2.314 46.723 1.00 50.28 ? 516 SER A C 1 ATOM 3637 O O . SER A 1 490 ? -59.504 -1.956 47.536 1.00 58.42 ? 516 SER A O 1 ATOM 3638 C CB . SER A 1 490 ? -59.041 -4.390 46.697 1.00 42.11 ? 516 SER A CB 1 ATOM 3639 O OG . SER A 1 490 ? -58.893 -5.654 46.085 1.00 57.08 ? 516 SER A OG 1 ATOM 3640 N N . ASN A 1 491 ? -61.173 -1.466 46.187 1.00 52.45 ? 517 ASN A N 1 ATOM 3641 C CA . ASN A 1 491 ? -61.166 -0.114 46.663 1.00 49.33 ? 517 ASN A CA 1 ATOM 3642 C C . ASN A 1 491 ? -62.058 0.023 47.864 1.00 45.35 ? 517 ASN A C 1 ATOM 3643 O O . ASN A 1 491 ? -63.279 -0.126 47.769 1.00 47.75 ? 517 ASN A O 1 ATOM 3644 C CB . ASN A 1 491 ? -61.571 0.855 45.558 1.00 50.04 ? 517 ASN A CB 1 ATOM 3645 C CG . ASN A 1 491 ? -61.557 2.278 46.021 1.00 47.00 ? 517 ASN A CG 1 ATOM 3646 O OD1 . ASN A 1 491 ? -61.761 2.557 47.184 1.00 56.44 ? 517 ASN A OD1 1 ATOM 3647 N ND2 . ASN A 1 491 ? -61.359 3.177 45.118 1.00 47.92 ? 517 ASN A ND2 1 ATOM 3648 N N . ALA A 1 492 ? -61.467 0.378 48.995 1.00 46.97 ? 518 ALA A N 1 ATOM 3649 C CA . ALA A 1 492 ? -62.248 0.533 50.238 1.00 48.96 ? 518 ALA A CA 1 ATOM 3650 C C . ALA A 1 492 ? -62.309 1.947 50.737 1.00 45.48 ? 518 ALA A C 1 ATOM 3651 O O . ALA A 1 492 ? -62.640 2.155 51.895 1.00 47.48 ? 518 ALA A O 1 ATOM 3652 C CB . ALA A 1 492 ? -61.655 -0.348 51.321 1.00 49.36 ? 518 ALA A CB 1 ATOM 3653 N N . GLN A 1 493 ? -62.118 2.923 49.850 1.00 48.52 ? 519 GLN A N 1 ATOM 3654 C CA . GLN A 1 493 ? -62.082 4.310 50.268 1.00 45.09 ? 519 GLN A CA 1 ATOM 3655 C C . GLN A 1 493 ? -63.412 4.959 50.439 1.00 51.74 ? 519 GLN A C 1 ATOM 3656 O O . GLN A 1 493 ? -64.433 4.422 50.004 1.00 49.04 ? 519 GLN A O 1 ATOM 3657 C CB . GLN A 1 493 ? -61.291 5.150 49.274 1.00 45.88 ? 519 GLN A CB 1 ATOM 3658 C CG . GLN A 1 493 ? -61.983 5.491 47.969 1.00 49.65 ? 519 GLN A CG 1 ATOM 3659 C CD . GLN A 1 493 ? -61.073 6.267 47.005 1.00 50.71 ? 519 GLN A CD 1 ATOM 3660 O OE1 . GLN A 1 493 ? -60.825 5.818 45.885 1.00 51.98 ? 519 GLN A OE1 1 ATOM 3661 N NE2 . GLN A 1 493 ? -60.422 7.293 47.506 1.00 56.26 ? 519 GLN A NE2 1 ATOM 3662 N N . VAL A 1 494 ? -63.374 6.131 51.092 1.00 51.22 ? 520 VAL A N 1 ATOM 3663 C CA . VAL A 1 494 ? -64.544 6.965 51.317 1.00 46.80 ? 520 VAL A CA 1 ATOM 3664 C C . VAL A 1 494 ? -64.482 8.076 50.286 1.00 55.63 ? 520 VAL A C 1 ATOM 3665 O O . VAL A 1 494 ? -63.655 8.965 50.408 1.00 54.84 ? 520 VAL A O 1 ATOM 3666 C CB . VAL A 1 494 ? -64.534 7.628 52.704 1.00 50.32 ? 520 VAL A CB 1 ATOM 3667 C CG1 . VAL A 1 494 ? -65.598 8.696 52.774 1.00 51.34 ? 520 VAL A CG1 1 ATOM 3668 C CG2 . VAL A 1 494 ? -64.763 6.601 53.814 1.00 51.44 ? 520 VAL A CG2 1 ATOM 3669 N N . LEU A 1 495 ? -65.280 7.970 49.218 1.00 63.19 ? 521 LEU A N 1 ATOM 3670 C CA . LEU A 1 495 ? -65.305 8.991 48.172 1.00 55.22 ? 521 LEU A CA 1 ATOM 3671 C C . LEU A 1 495 ? -65.805 10.274 48.785 1.00 60.81 ? 521 LEU A C 1 ATOM 3672 O O . LEU A 1 495 ? -66.795 10.269 49.502 1.00 63.37 ? 521 LEU A O 1 ATOM 3673 C CB . LEU A 1 495 ? -66.162 8.558 47.008 1.00 54.00 ? 521 LEU A CB 1 ATOM 3674 C CG . LEU A 1 495 ? -65.581 7.398 46.204 1.00 56.17 ? 521 LEU A CG 1 ATOM 3675 C CD1 . LEU A 1 495 ? -66.571 6.926 45.166 1.00 57.82 ? 521 LEU A CD1 1 ATOM 3676 C CD2 . LEU A 1 495 ? -64.268 7.766 45.538 1.00 53.92 ? 521 LEU A CD2 1 ATOM 3677 N N . SER A 1 496 ? -65.146 11.383 48.470 1.00 63.22 ? 522 SER A N 1 ATOM 3678 C CA . SER A 1 496 ? -65.511 12.659 49.081 1.00 70.85 ? 522 SER A CA 1 ATOM 3679 C C . SER A 1 496 ? -65.908 13.825 48.190 1.00 72.94 ? 522 SER A C 1 ATOM 3680 O O . SER A 1 496 ? -66.305 14.860 48.695 1.00 72.43 ? 522 SER A O 1 ATOM 3681 C CB . SER A 1 496 ? -64.362 13.077 49.961 1.00 68.77 ? 522 SER A CB 1 ATOM 3682 O OG . SER A 1 496 ? -63.175 13.020 49.211 1.00 58.74 ? 522 SER A OG 1 ATOM 3683 N N . GLY A 1 497 ? -65.828 13.662 46.879 1.00 76.83 ? 523 GLY A N 1 ATOM 3684 C CA . GLY A 1 497 ? -66.218 14.733 45.970 1.00 63.17 ? 523 GLY A CA 1 ATOM 3685 C C . GLY A 1 497 ? -65.077 15.402 45.233 1.00 59.21 ? 523 GLY A C 1 ATOM 3686 O O . GLY A 1 497 ? -65.306 16.359 44.502 1.00 60.20 ? 523 GLY A O 1 ATOM 3687 N N . THR A 1 498 ? -63.864 14.876 45.378 1.00 51.38 ? 524 THR A N 1 ATOM 3688 C CA . THR A 1 498 ? -62.683 15.437 44.715 1.00 52.18 ? 524 THR A CA 1 ATOM 3689 C C . THR A 1 498 ? -61.883 14.418 43.911 1.00 54.94 ? 524 THR A C 1 ATOM 3690 O O . THR A 1 498 ? -60.997 14.770 43.125 1.00 61.95 ? 524 THR A O 1 ATOM 3691 C CB . THR A 1 498 ? -61.675 15.976 45.782 1.00 59.82 ? 524 THR A CB 1 ATOM 3692 O OG1 . THR A 1 498 ? -61.142 14.888 46.571 1.00 50.61 ? 524 THR A OG1 1 ATOM 3693 C CG2 . THR A 1 498 ? -62.353 16.987 46.704 1.00 56.88 ? 524 THR A CG2 1 ATOM 3694 N N . GLU A 1 499 ? -62.138 13.148 44.153 1.00 61.29 ? 525 GLU A N 1 ATOM 3695 C CA . GLU A 1 499 ? -61.380 12.117 43.492 1.00 53.75 ? 525 GLU A CA 1 ATOM 3696 C C . GLU A 1 499 ? -61.408 12.179 42.000 1.00 49.49 ? 525 GLU A C 1 ATOM 3697 O O . GLU A 1 499 ? -60.430 11.792 41.413 1.00 49.71 ? 525 GLU A O 1 ATOM 3698 C CB . GLU A 1 499 ? -61.775 10.711 43.979 1.00 56.95 ? 525 GLU A CB 1 ATOM 3699 C CG . GLU A 1 499 ? -61.572 10.466 45.477 1.00 48.64 ? 525 GLU A CG 1 ATOM 3700 C CD . GLU A 1 499 ? -62.562 11.220 46.349 1.00 51.76 ? 525 GLU A CD 1 ATOM 3701 O OE1 . GLU A 1 499 ? -63.648 11.584 45.862 1.00 66.41 ? 525 GLU A OE1 1 ATOM 3702 O OE2 . GLU A 1 499 ? -62.317 11.362 47.554 1.00 58.28 ? 525 GLU A OE2 1 ATOM 3703 N N . PHE A 1 500 ? -62.506 12.661 41.391 1.00 45.13 ? 526 PHE A N 1 ATOM 3704 C CA . PHE A 1 500 ? -62.626 12.739 39.911 1.00 46.70 ? 526 PHE A CA 1 ATOM 3705 C C . PHE A 1 500 ? -62.590 14.173 39.314 1.00 56.33 ? 526 PHE A C 1 ATOM 3706 O O . PHE A 1 500 ? -63.001 14.417 38.161 1.00 49.60 ? 526 PHE A O 1 ATOM 3707 C CB . PHE A 1 500 ? -63.920 12.063 39.448 1.00 51.23 ? 526 PHE A CB 1 ATOM 3708 C CG . PHE A 1 500 ? -64.018 10.604 39.800 1.00 48.91 ? 526 PHE A CG 1 ATOM 3709 C CD1 . PHE A 1 500 ? -64.665 10.201 40.942 1.00 57.16 ? 526 PHE A CD1 1 ATOM 3710 C CD2 . PHE A 1 500 ? -63.493 9.646 38.975 1.00 55.42 ? 526 PHE A CD2 1 ATOM 3711 C CE1 . PHE A 1 500 ? -64.725 8.870 41.287 1.00 49.10 ? 526 PHE A CE1 1 ATOM 3712 C CE2 . PHE A 1 500 ? -63.587 8.301 39.291 1.00 51.28 ? 526 PHE A CE2 1 ATOM 3713 C CZ . PHE A 1 500 ? -64.185 7.924 40.455 1.00 49.38 ? 526 PHE A CZ 1 ATOM 3714 N N . SER A 1 501 ? -61.976 15.095 40.028 1.00 59.58 ? 527 SER A N 1 ATOM 3715 C CA . SER A 1 501 ? -61.915 16.461 39.561 1.00 55.72 ? 527 SER A CA 1 ATOM 3716 C C . SER A 1 501 ? -61.206 16.609 38.202 1.00 51.72 ? 527 SER A C 1 ATOM 3717 O O . SER A 1 501 ? -61.577 17.471 37.433 1.00 65.77 ? 527 SER A O 1 ATOM 3718 C CB . SER A 1 501 ? -61.224 17.327 40.599 1.00 56.44 ? 527 SER A CB 1 ATOM 3719 O OG . SER A 1 501 ? -59.862 16.960 40.728 1.00 66.28 ? 527 SER A OG 1 ATOM 3720 N N . ALA A 1 502 ? -60.180 15.798 37.931 1.00 45.05 ? 528 ALA A N 1 ATOM 3721 C CA . ALA A 1 502 ? -59.436 15.858 36.653 1.00 43.69 ? 528 ALA A CA 1 ATOM 3722 C C . ALA A 1 502 ? -60.168 15.261 35.459 1.00 52.61 ? 528 ALA A C 1 ATOM 3723 O O . ALA A 1 502 ? -59.694 15.389 34.343 1.00 57.18 ? 528 ALA A O 1 ATOM 3724 C CB . ALA A 1 502 ? -58.049 15.218 36.766 1.00 40.76 ? 528 ALA A CB 1 ATOM 3725 N N . ILE A 1 503 ? -61.248 14.519 35.696 1.00 53.66 ? 529 ILE A N 1 ATOM 3726 C CA . ILE A 1 503 ? -62.035 13.938 34.597 1.00 48.00 ? 529 ILE A CA 1 ATOM 3727 C C . ILE A 1 503 ? -63.469 14.113 35.026 1.00 56.52 ? 529 ILE A C 1 ATOM 3728 O O . ILE A 1 503 ? -64.206 13.164 35.227 1.00 57.81 ? 529 ILE A O 1 ATOM 3729 C CB . ILE A 1 503 ? -61.697 12.483 34.350 1.00 45.52 ? 529 ILE A CB 1 ATOM 3730 C CG1 . ILE A 1 503 ? -61.781 11.691 35.660 1.00 52.28 ? 529 ILE A CG1 1 ATOM 3731 C CG2 . ILE A 1 503 ? -60.265 12.358 33.833 1.00 46.92 ? 529 ILE A CG2 1 ATOM 3732 C CD1 . ILE A 1 503 ? -61.477 10.212 35.501 1.00 54.68 ? 529 ILE A CD1 1 ATOM 3733 N N . PRO A 1 504 ? -63.889 15.362 35.117 1.00 58.57 ? 530 PRO A N 1 ATOM 3734 C CA . PRO A 1 504 ? -65.222 15.636 35.586 1.00 57.82 ? 530 PRO A CA 1 ATOM 3735 C C . PRO A 1 504 ? -66.306 15.429 34.585 1.00 56.93 ? 530 PRO A C 1 ATOM 3736 O O . PRO A 1 504 ? -67.465 15.596 34.935 1.00 55.86 ? 530 PRO A O 1 ATOM 3737 C CB . PRO A 1 504 ? -65.143 17.105 35.984 1.00 56.84 ? 530 PRO A CB 1 ATOM 3738 C CG . PRO A 1 504 ? -64.081 17.682 35.096 1.00 50.56 ? 530 PRO A CG 1 ATOM 3739 C CD . PRO A 1 504 ? -63.225 16.563 34.588 1.00 49.45 ? 530 PRO A CD 1 ATOM 3740 N N . HIS A 1 505 ? -65.986 14.999 33.372 1.00 55.94 ? 531 HIS A N 1 ATOM 3741 C CA . HIS A 1 505 ? -67.079 14.813 32.412 1.00 60.49 ? 531 HIS A CA 1 ATOM 3742 C C . HIS A 1 505 ? -67.492 13.358 32.191 1.00 56.85 ? 531 HIS A C 1 ATOM 3743 O O . HIS A 1 505 ? -68.208 13.038 31.254 1.00 63.78 ? 531 HIS A O 1 ATOM 3744 C CB . HIS A 1 505 ? -66.796 15.555 31.108 1.00 63.53 ? 531 HIS A CB 1 ATOM 3745 C CG . HIS A 1 505 ? -66.385 16.982 31.325 1.00 71.99 ? 531 HIS A CG 1 ATOM 3746 N ND1 . HIS A 1 505 ? -67.217 17.915 31.910 1.00 72.44 ? 531 HIS A ND1 1 ATOM 3747 C CD2 . HIS A 1 505 ? -65.239 17.637 31.022 1.00 61.72 ? 531 HIS A CD2 1 ATOM 3748 C CE1 . HIS A 1 505 ? -66.588 19.072 31.995 1.00 61.98 ? 531 HIS A CE1 1 ATOM 3749 N NE2 . HIS A 1 505 ? -65.385 18.928 31.468 1.00 67.52 ? 531 HIS A NE2 1 ATOM 3750 N N . VAL A 1 506 ? -67.165 12.501 33.138 1.00 54.85 ? 532 VAL A N 1 ATOM 3751 C CA . VAL A 1 506 ? -67.538 11.123 33.014 1.00 49.01 ? 532 VAL A CA 1 ATOM 3752 C C . VAL A 1 506 ? -69.042 11.022 33.019 1.00 46.97 ? 532 VAL A C 1 ATOM 3753 O O . VAL A 1 506 ? -69.706 11.665 33.837 1.00 47.39 ? 532 VAL A O 1 ATOM 3754 C CB . VAL A 1 506 ? -66.976 10.302 34.164 1.00 48.87 ? 532 VAL A CB 1 ATOM 3755 C CG1 . VAL A 1 506 ? -67.535 8.894 34.113 1.00 42.51 ? 532 VAL A CG1 1 ATOM 3756 C CG2 . VAL A 1 506 ? -65.451 10.296 34.108 1.00 46.55 ? 532 VAL A CG2 1 ATOM 3757 N N . LYS A 1 507 ? -69.586 10.231 32.096 1.00 48.31 ? 533 LYS A N 1 ATOM 3758 C CA . LYS A 1 507 ? -71.048 10.051 31.991 1.00 52.26 ? 533 LYS A CA 1 ATOM 3759 C C . LYS A 1 507 ? -71.506 8.705 32.543 1.00 50.19 ? 533 LYS A C 1 ATOM 3760 O O . LYS A 1 507 ? -72.637 8.552 33.033 1.00 43.86 ? 533 LYS A O 1 ATOM 3761 C CB . LYS A 1 507 ? -71.437 10.049 30.530 1.00 64.78 ? 533 LYS A CB 1 ATOM 3762 C CG . LYS A 1 507 ? -71.092 11.281 29.739 1.00 68.11 ? 533 LYS A CG 1 ATOM 3763 C CD . LYS A 1 507 ? -71.875 12.488 30.189 1.00 76.13 ? 533 LYS A CD 1 ATOM 3764 C CE . LYS A 1 507 ? -71.599 13.637 29.240 1.00 84.46 ? 533 LYS A CE 1 ATOM 3765 N NZ . LYS A 1 507 ? -72.084 13.319 27.869 1.00 88.52 ? 533 LYS A NZ 1 ATOM 3766 N N . TYR A 1 508 ? -70.675 7.702 32.306 1.00 49.67 ? 534 TYR A N 1 ATOM 3767 C CA . TYR A 1 508 ? -70.956 6.357 32.737 1.00 53.00 ? 534 TYR A CA 1 ATOM 3768 C C . TYR A 1 508 ? -69.792 5.934 33.634 1.00 46.65 ? 534 TYR A C 1 ATOM 3769 O O . TYR A 1 508 ? -68.633 5.888 33.188 1.00 41.15 ? 534 TYR A O 1 ATOM 3770 C CB . TYR A 1 508 ? -71.019 5.442 31.509 1.00 53.86 ? 534 TYR A CB 1 ATOM 3771 C CG . TYR A 1 508 ? -71.577 4.056 31.761 1.00 56.12 ? 534 TYR A CG 1 ATOM 3772 C CD1 . TYR A 1 508 ? -70.893 3.130 32.528 1.00 62.59 ? 534 TYR A CD1 1 ATOM 3773 C CD2 . TYR A 1 508 ? -72.684 3.616 31.067 1.00 59.92 ? 534 TYR A CD2 1 ATOM 3774 C CE1 . TYR A 1 508 ? -71.388 1.850 32.707 1.00 61.79 ? 534 TYR A CE1 1 ATOM 3775 C CE2 . TYR A 1 508 ? -73.182 2.349 31.243 1.00 61.03 ? 534 TYR A CE2 1 ATOM 3776 C CZ . TYR A 1 508 ? -72.526 1.473 32.056 1.00 59.40 ? 534 TYR A CZ 1 ATOM 3777 O OH . TYR A 1 508 ? -73.010 0.212 32.180 1.00 54.98 ? 534 TYR A OH 1 ATOM 3778 N N . LEU A 1 509 ? -70.087 5.642 34.893 1.00 41.34 ? 535 LEU A N 1 ATOM 3779 C CA . LEU A 1 509 ? -69.035 5.230 35.823 1.00 43.05 ? 535 LEU A CA 1 ATOM 3780 C C . LEU A 1 509 ? -69.347 3.872 36.420 1.00 41.44 ? 535 LEU A C 1 ATOM 3781 O O . LEU A 1 509 ? -70.400 3.686 37.037 1.00 41.02 ? 535 LEU A O 1 ATOM 3782 C CB . LEU A 1 509 ? -68.928 6.242 36.957 1.00 43.91 ? 535 LEU A CB 1 ATOM 3783 C CG . LEU A 1 509 ? -67.905 5.942 38.036 1.00 46.52 ? 535 LEU A CG 1 ATOM 3784 C CD1 . LEU A 1 509 ? -66.521 5.864 37.402 1.00 49.01 ? 535 LEU A CD1 1 ATOM 3785 C CD2 . LEU A 1 509 ? -67.957 7.027 39.111 1.00 43.13 ? 535 LEU A CD2 1 ATOM 3786 N N . ASP A 1 510 ? -68.415 2.944 36.260 1.00 44.06 ? 536 ASP A N 1 ATOM 3787 C CA . ASP A 1 510 ? -68.562 1.603 36.790 1.00 48.90 ? 536 ASP A CA 1 ATOM 3788 C C . ASP A 1 510 ? -67.640 1.417 38.005 1.00 47.22 ? 536 ASP A C 1 ATOM 3789 O O . ASP A 1 510 ? -66.422 1.378 37.874 1.00 41.69 ? 536 ASP A O 1 ATOM 3790 C CB . ASP A 1 510 ? -68.256 0.572 35.716 1.00 47.82 ? 536 ASP A CB 1 ATOM 3791 C CG . ASP A 1 510 ? -68.604 -0.839 36.149 1.00 58.34 ? 536 ASP A CG 1 ATOM 3792 O OD1 . ASP A 1 510 ? -68.638 -1.104 37.376 1.00 49.80 ? 536 ASP A OD1 1 ATOM 3793 O OD2 . ASP A 1 510 ? -68.834 -1.686 35.250 1.00 63.33 ? 536 ASP A OD2 1 ATOM 3794 N N . LEU A 1 511 ? -68.255 1.270 39.153 1.00 40.48 ? 537 LEU A N 1 ATOM 3795 C CA . LEU A 1 511 ? -67.550 1.105 40.380 1.00 45.52 ? 537 LEU A CA 1 ATOM 3796 C C . LEU A 1 511 ? -67.887 -0.219 41.011 1.00 45.53 ? 537 LEU A C 1 ATOM 3797 O O . LEU A 1 511 ? -67.784 -0.359 42.184 1.00 43.33 ? 537 LEU A O 1 ATOM 3798 C CB . LEU A 1 511 ? -67.919 2.230 41.321 1.00 43.49 ? 537 LEU A CB 1 ATOM 3799 C CG . LEU A 1 511 ? -67.330 3.589 41.013 1.00 44.19 ? 537 LEU A CG 1 ATOM 3800 C CD1 . LEU A 1 511 ? -67.733 4.583 42.054 1.00 49.35 ? 537 LEU A CD1 1 ATOM 3801 C CD2 . LEU A 1 511 ? -65.835 3.508 40.976 1.00 50.19 ? 537 LEU A CD2 1 ATOM 3802 N N . THR A 1 512 ? -68.335 -1.180 40.232 1.00 38.96 ? 538 THR A N 1 ATOM 3803 C CA . THR A 1 512 ? -68.797 -2.429 40.774 1.00 34.94 ? 538 THR A CA 1 ATOM 3804 C C . THR A 1 512 ? -67.692 -3.262 41.341 1.00 43.64 ? 538 THR A C 1 ATOM 3805 O O . THR A 1 512 ? -66.550 -3.095 41.007 1.00 38.16 ? 538 THR A O 1 ATOM 3806 C CB . THR A 1 512 ? -69.502 -3.269 39.727 1.00 37.40 ? 538 THR A CB 1 ATOM 3807 O OG1 . THR A 1 512 ? -68.583 -3.625 38.714 1.00 38.76 ? 538 THR A OG1 1 ATOM 3808 C CG2 . THR A 1 512 ? -70.569 -2.526 39.133 1.00 36.23 ? 538 THR A CG2 1 ATOM 3809 N N . ASN A 1 513 ? -68.071 -4.174 42.212 1.00 41.64 ? 539 ASN A N 1 ATOM 3810 C CA . ASN A 1 513 ? -67.175 -5.134 42.811 1.00 44.13 ? 539 ASN A CA 1 ATOM 3811 C C . ASN A 1 513 ? -65.978 -4.615 43.564 1.00 37.11 ? 539 ASN A C 1 ATOM 3812 O O . ASN A 1 513 ? -64.883 -5.060 43.377 1.00 43.88 ? 539 ASN A O 1 ATOM 3813 C CB . ASN A 1 513 ? -66.772 -6.198 41.812 1.00 43.86 ? 539 ASN A CB 1 ATOM 3814 C CG . ASN A 1 513 ? -66.434 -7.491 42.476 1.00 55.81 ? 539 ASN A CG 1 ATOM 3815 O OD1 . ASN A 1 513 ? -66.635 -7.645 43.659 1.00 65.37 ? 539 ASN A OD1 1 ATOM 3816 N ND2 . ASN A 1 513 ? -65.906 -8.418 41.731 1.00 69.55 ? 539 ASN A ND2 1 ATOM 3817 N N . ASN A 1 514 ? -66.225 -3.666 44.436 1.00 40.24 ? 540 ASN A N 1 ATOM 3818 C CA . ASN A 1 514 ? -65.213 -3.051 45.260 1.00 40.24 ? 540 ASN A CA 1 ATOM 3819 C C . ASN A 1 514 ? -65.738 -3.085 46.663 1.00 41.21 ? 540 ASN A C 1 ATOM 3820 O O . ASN A 1 514 ? -66.682 -3.760 46.899 1.00 42.00 ? 540 ASN A O 1 ATOM 3821 C CB . ASN A 1 514 ? -64.973 -1.634 44.810 1.00 39.78 ? 540 ASN A CB 1 ATOM 3822 C CG . ASN A 1 514 ? -64.061 -1.555 43.645 1.00 37.52 ? 540 ASN A CG 1 ATOM 3823 O OD1 . ASN A 1 514 ? -62.920 -1.876 43.738 1.00 43.82 ? 540 ASN A OD1 1 ATOM 3824 N ND2 . ASN A 1 514 ? -64.565 -1.123 42.551 1.00 39.15 ? 540 ASN A ND2 1 ATOM 3825 N N . ARG A 1 515 ? -65.103 -2.417 47.607 1.00 46.66 ? 541 ARG A N 1 ATOM 3826 C CA . ARG A 1 515 ? -65.678 -2.298 48.933 1.00 47.41 ? 541 ARG A CA 1 ATOM 3827 C C . ARG A 1 515 ? -65.711 -0.875 49.382 1.00 48.83 ? 541 ARG A C 1 ATOM 3828 O O . ARG A 1 515 ? -65.273 -0.533 50.435 1.00 54.57 ? 541 ARG A O 1 ATOM 3829 C CB . ARG A 1 515 ? -64.966 -3.168 49.946 1.00 47.19 ? 541 ARG A CB 1 ATOM 3830 C CG . ARG A 1 515 ? -63.654 -3.714 49.520 1.00 49.42 ? 541 ARG A CG 1 ATOM 3831 C CD . ARG A 1 515 ? -63.081 -4.470 50.677 1.00 60.45 ? 541 ARG A CD 1 ATOM 3832 N NE . ARG A 1 515 ? -63.362 -5.884 50.606 1.00 62.20 ? 541 ARG A NE 1 ATOM 3833 C CZ . ARG A 1 515 ? -62.829 -6.772 51.414 1.00 62.52 ? 541 ARG A CZ 1 ATOM 3834 N NH1 . ARG A 1 515 ? -62.002 -6.391 52.340 1.00 67.55 ? 541 ARG A NH1 1 ATOM 3835 N NH2 . ARG A 1 515 ? -63.121 -8.034 51.293 1.00 54.83 ? 541 ARG A NH2 1 ATOM 3836 N N . LEU A 1 516 ? -66.329 -0.054 48.577 1.00 51.45 ? 542 LEU A N 1 ATOM 3837 C CA . LEU A 1 516 ? -66.410 1.372 48.852 1.00 50.35 ? 542 LEU A CA 1 ATOM 3838 C C . LEU A 1 516 ? -67.195 1.649 50.103 1.00 50.88 ? 542 LEU A C 1 ATOM 3839 O O . LEU A 1 516 ? -68.172 0.965 50.429 1.00 54.35 ? 542 LEU A O 1 ATOM 3840 C CB . LEU A 1 516 ? -66.996 2.124 47.667 1.00 46.21 ? 542 LEU A CB 1 ATOM 3841 C CG . LEU A 1 516 ? -66.176 2.035 46.376 1.00 44.63 ? 542 LEU A CG 1 ATOM 3842 C CD1 . LEU A 1 516 ? -67.024 2.408 45.159 1.00 48.15 ? 542 LEU A CD1 1 ATOM 3843 C CD2 . LEU A 1 516 ? -64.905 2.872 46.460 1.00 49.46 ? 542 LEU A CD2 1 ATOM 3844 N N . ASP A 1 517 ? -66.760 2.697 50.783 1.00 55.51 ? 543 ASP A N 1 ATOM 3845 C CA . ASP A 1 517 ? -67.331 3.119 52.018 1.00 52.17 ? 543 ASP A CA 1 ATOM 3846 C C . ASP A 1 517 ? -68.017 4.442 51.810 1.00 51.41 ? 543 ASP A C 1 ATOM 3847 O O . ASP A 1 517 ? -67.384 5.482 51.776 1.00 57.03 ? 543 ASP A O 1 ATOM 3848 C CB . ASP A 1 517 ? -66.212 3.240 53.047 1.00 59.14 ? 543 ASP A CB 1 ATOM 3849 C CG . ASP A 1 517 ? -66.712 3.648 54.445 1.00 70.83 ? 543 ASP A CG 1 ATOM 3850 O OD1 . ASP A 1 517 ? -67.955 3.835 54.667 1.00 65.51 ? 543 ASP A OD1 1 ATOM 3851 O OD2 . ASP A 1 517 ? -65.831 3.766 55.328 1.00 60.35 ? 543 ASP A OD2 1 ATOM 3852 N N . PHE A 1 518 ? -69.329 4.378 51.687 1.00 48.64 ? 544 PHE A N 1 ATOM 3853 C CA . PHE A 1 518 ? -70.144 5.538 51.479 1.00 56.32 ? 544 PHE A CA 1 ATOM 3854 C C . PHE A 1 518 ? -70.431 6.253 52.756 1.00 58.68 ? 544 PHE A C 1 ATOM 3855 O O . PHE A 1 518 ? -71.543 6.199 53.285 1.00 57.33 ? 544 PHE A O 1 ATOM 3856 C CB . PHE A 1 518 ? -71.421 5.166 50.717 1.00 60.27 ? 544 PHE A CB 1 ATOM 3857 C CG . PHE A 1 518 ? -71.135 4.742 49.331 1.00 54.34 ? 544 PHE A CG 1 ATOM 3858 C CD1 . PHE A 1 518 ? -70.815 5.696 48.379 1.00 56.19 ? 544 PHE A CD1 1 ATOM 3859 C CD2 . PHE A 1 518 ? -71.033 3.410 49.008 1.00 58.08 ? 544 PHE A CD2 1 ATOM 3860 C CE1 . PHE A 1 518 ? -70.446 5.330 47.106 1.00 61.15 ? 544 PHE A CE1 1 ATOM 3861 C CE2 . PHE A 1 518 ? -70.654 3.030 47.740 1.00 60.65 ? 544 PHE A CE2 1 ATOM 3862 C CZ . PHE A 1 518 ? -70.351 3.990 46.787 1.00 60.66 ? 544 PHE A CZ 1 ATOM 3863 N N . ASP A 1 519 ? -69.439 7.011 53.202 1.00 65.49 ? 545 ASP A N 1 ATOM 3864 C CA . ASP A 1 519 ? -69.577 7.732 54.438 1.00 69.13 ? 545 ASP A CA 1 ATOM 3865 C C . ASP A 1 519 ? -69.332 9.223 54.274 1.00 70.11 ? 545 ASP A C 1 ATOM 3866 O O . ASP A 1 519 ? -68.708 9.836 55.122 1.00 79.27 ? 545 ASP A O 1 ATOM 3867 C CB . ASP A 1 519 ? -68.579 7.181 55.425 1.00 64.40 ? 545 ASP A CB 1 ATOM 3868 C CG . ASP A 1 519 ? -68.888 7.587 56.811 1.00 73.17 ? 545 ASP A CG 1 ATOM 3869 O OD1 . ASP A 1 519 ? -70.102 7.709 57.124 1.00 66.66 ? 545 ASP A OD1 1 ATOM 3870 O OD2 . ASP A 1 519 ? -67.938 7.663 57.608 1.00 87.75 ? 545 ASP A OD2 1 ATOM 3871 N N . ASN A 1 520 ? -69.813 9.795 53.174 1.00 78.51 ? 546 ASN A N 1 ATOM 3872 C CA . ASN A 1 520 ? -69.648 11.226 52.888 1.00 63.39 ? 546 ASN A CA 1 ATOM 3873 C C . ASN A 1 520 ? -70.616 11.686 51.781 1.00 60.20 ? 546 ASN A C 1 ATOM 3874 O O . ASN A 1 520 ? -70.468 11.348 50.609 1.00 66.08 ? 546 ASN A O 1 ATOM 3875 C CB . ASN A 1 520 ? -68.195 11.549 52.534 1.00 60.68 ? 546 ASN A CB 1 ATOM 3876 C CG . ASN A 1 520 ? -67.965 13.038 52.284 1.00 65.77 ? 546 ASN A CG 1 ATOM 3877 O OD1 . ASN A 1 520 ? -68.602 13.652 51.428 1.00 67.82 ? 546 ASN A OD1 1 ATOM 3878 N ND2 . ASN A 1 520 ? -67.007 13.600 52.986 1.00 69.80 ? 546 ASN A ND2 1 ATOM 3879 N N . ALA A 1 521 ? -71.604 12.461 52.199 1.00 59.38 ? 547 ALA A N 1 ATOM 3880 C CA . ALA A 1 521 ? -72.641 12.997 51.338 1.00 68.92 ? 547 ALA A CA 1 ATOM 3881 C C . ALA A 1 521 ? -72.165 13.711 50.053 1.00 68.29 ? 547 ALA A C 1 ATOM 3882 O O . ALA A 1 521 ? -72.952 13.913 49.136 1.00 68.41 ? 547 ALA A O 1 ATOM 3883 C CB . ALA A 1 521 ? -73.541 13.923 52.156 1.00 63.12 ? 547 ALA A CB 1 ATOM 3884 N N . SER A 1 522 ? -70.911 14.127 49.999 1.00 55.10 ? 548 SER A N 1 ATOM 3885 C CA . SER A 1 522 ? -70.412 14.810 48.809 1.00 59.95 ? 548 SER A CA 1 ATOM 3886 C C . SER A 1 522 ? -69.827 13.841 47.782 1.00 66.22 ? 548 SER A C 1 ATOM 3887 O O . SER A 1 522 ? -69.253 14.263 46.770 1.00 52.29 ? 548 SER A O 1 ATOM 3888 C CB . SER A 1 522 ? -69.306 15.795 49.216 1.00 60.71 ? 548 SER A CB 1 ATOM 3889 O OG . SER A 1 522 ? -69.787 16.750 50.141 1.00 67.34 ? 548 SER A OG 1 ATOM 3890 N N . ALA A 1 523 ? -69.918 12.546 48.062 1.00 65.78 ? 549 ALA A N 1 ATOM 3891 C CA . ALA A 1 523 ? -69.351 11.542 47.167 1.00 60.25 ? 549 ALA A CA 1 ATOM 3892 C C . ALA A 1 523 ? -69.744 11.710 45.706 1.00 54.98 ? 549 ALA A C 1 ATOM 3893 O O . ALA A 1 523 ? -70.917 11.850 45.409 1.00 47.26 ? 549 ALA A O 1 ATOM 3894 C CB . ALA A 1 523 ? -69.757 10.161 47.634 1.00 55.04 ? 549 ALA A CB 1 ATOM 3895 N N . LEU A 1 524 ? -68.749 11.762 44.816 1.00 55.22 ? 550 LEU A N 1 ATOM 3896 C CA . LEU A 1 524 ? -68.980 11.840 43.359 1.00 57.87 ? 550 LEU A CA 1 ATOM 3897 C C . LEU A 1 524 ? -69.716 13.086 42.808 1.00 63.56 ? 550 LEU A C 1 ATOM 3898 O O . LEU A 1 524 ? -69.948 13.196 41.583 1.00 56.71 ? 550 LEU A O 1 ATOM 3899 C CB . LEU A 1 524 ? -69.754 10.573 42.930 1.00 56.08 ? 550 LEU A CB 1 ATOM 3900 C CG . LEU A 1 524 ? -69.093 9.232 43.282 1.00 53.82 ? 550 LEU A CG 1 ATOM 3901 C CD1 . LEU A 1 524 ? -70.080 8.100 43.174 1.00 59.46 ? 550 LEU A CD1 1 ATOM 3902 C CD2 . LEU A 1 524 ? -67.849 8.956 42.452 1.00 49.34 ? 550 LEU A CD2 1 ATOM 3903 N N . THR A 1 525 ? -70.040 14.042 43.676 1.00 60.83 ? 551 THR A N 1 ATOM 3904 C CA . THR A 1 525 ? -70.741 15.244 43.224 1.00 56.57 ? 551 THR A CA 1 ATOM 3905 C C . THR A 1 525 ? -69.923 16.043 42.233 1.00 56.29 ? 551 THR A C 1 ATOM 3906 O O . THR A 1 525 ? -70.475 16.801 41.453 1.00 66.93 ? 551 THR A O 1 ATOM 3907 C CB . THR A 1 525 ? -71.179 16.144 44.368 1.00 56.12 ? 551 THR A CB 1 ATOM 3908 O OG1 . THR A 1 525 ? -70.042 16.498 45.150 1.00 58.17 ? 551 THR A OG1 1 ATOM 3909 C CG2 . THR A 1 525 ? -72.200 15.440 45.231 1.00 57.04 ? 551 THR A CG2 1 ATOM 3910 N N . GLU A 1 526 ? -68.626 15.802 42.168 1.00 58.16 ? 552 GLU A N 1 ATOM 3911 C CA . GLU A 1 526 ? -67.836 16.527 41.201 1.00 51.94 ? 552 GLU A CA 1 ATOM 3912 C C . GLU A 1 526 ? -68.125 16.095 39.780 1.00 54.64 ? 552 GLU A C 1 ATOM 3913 O O . GLU A 1 526 ? -67.568 16.680 38.867 1.00 61.46 ? 552 GLU A O 1 ATOM 3914 C CB . GLU A 1 526 ? -66.346 16.408 41.440 1.00 47.64 ? 552 GLU A CB 1 ATOM 3915 C CG . GLU A 1 526 ? -65.717 15.027 41.257 1.00 61.55 ? 552 GLU A CG 1 ATOM 3916 C CD . GLU A 1 526 ? -65.930 14.023 42.401 1.00 60.39 ? 552 GLU A CD 1 ATOM 3917 O OE1 . GLU A 1 526 ? -67.046 13.908 42.986 1.00 47.57 ? 552 GLU A OE1 1 ATOM 3918 O OE2 . GLU A 1 526 ? -64.955 13.261 42.620 1.00 54.67 ? 552 GLU A OE2 1 ATOM 3919 N N . LEU A 1 527 ? -68.869 14.998 39.589 1.00 60.55 ? 553 LEU A N 1 ATOM 3920 C CA . LEU A 1 527 ? -69.223 14.507 38.220 1.00 52.62 ? 553 LEU A CA 1 ATOM 3921 C C . LEU A 1 527 ? -70.625 15.008 37.838 1.00 57.86 ? 553 LEU A C 1 ATOM 3922 O O . LEU A 1 527 ? -71.617 14.260 37.797 1.00 52.16 ? 553 LEU A O 1 ATOM 3923 C CB . LEU A 1 527 ? -69.189 12.993 38.160 1.00 47.66 ? 553 LEU A CB 1 ATOM 3924 C CG . LEU A 1 527 ? -67.854 12.338 38.412 1.00 49.63 ? 553 LEU A CG 1 ATOM 3925 C CD1 . LEU A 1 527 ? -68.012 10.826 38.470 1.00 48.57 ? 553 LEU A CD1 1 ATOM 3926 C CD2 . LEU A 1 527 ? -66.842 12.736 37.355 1.00 52.99 ? 553 LEU A CD2 1 ATOM 3927 N N . SER A 1 528 ? -70.695 16.304 37.608 1.00 61.89 ? 554 SER A N 1 ATOM 3928 C CA . SER A 1 528 ? -71.926 16.984 37.251 1.00 56.11 ? 554 SER A CA 1 ATOM 3929 C C . SER A 1 528 ? -72.663 16.392 36.070 1.00 51.63 ? 554 SER A C 1 ATOM 3930 O O . SER A 1 528 ? -73.879 16.410 36.058 1.00 56.17 ? 554 SER A O 1 ATOM 3931 C CB . SER A 1 528 ? -71.586 18.432 36.983 1.00 57.06 ? 554 SER A CB 1 ATOM 3932 O OG . SER A 1 528 ? -70.461 18.464 36.125 1.00 79.00 ? 554 SER A OG 1 ATOM 3933 N N . ASP A 1 529 ? -71.949 15.782 35.127 1.00 48.61 ? 555 ASP A N 1 ATOM 3934 C CA . ASP A 1 529 ? -72.590 15.191 33.931 1.00 52.32 ? 555 ASP A CA 1 ATOM 3935 C C . ASP A 1 529 ? -73.010 13.725 34.049 1.00 59.12 ? 555 ASP A C 1 ATOM 3936 O O . ASP A 1 529 ? -73.641 13.182 33.140 1.00 68.86 ? 555 ASP A O 1 ATOM 3937 C CB . ASP A 1 529 ? -71.617 15.274 32.748 1.00 58.54 ? 555 ASP A CB 1 ATOM 3938 C CG . ASP A 1 529 ? -71.198 16.703 32.427 1.00 64.46 ? 555 ASP A CG 1 ATOM 3939 O OD1 . ASP A 1 529 ? -71.971 17.618 32.711 1.00 63.37 ? 555 ASP A OD1 1 ATOM 3940 O OD2 . ASP A 1 529 ? -70.129 16.904 31.818 1.00 71.76 ? 555 ASP A OD2 1 ATOM 3941 N N . LEU A 1 530 ? -72.685 13.084 35.161 1.00 59.59 ? 556 LEU A N 1 ATOM 3942 C CA . LEU A 1 530 ? -72.985 11.675 35.323 1.00 55.51 ? 556 LEU A CA 1 ATOM 3943 C C . LEU A 1 530 ? -74.418 11.230 34.939 1.00 50.51 ? 556 LEU A C 1 ATOM 3944 O O . LEU A 1 530 ? -75.390 11.753 35.445 1.00 51.94 ? 556 LEU A O 1 ATOM 3945 C CB . LEU A 1 530 ? -72.712 11.291 36.747 1.00 55.76 ? 556 LEU A CB 1 ATOM 3946 C CG . LEU A 1 530 ? -72.611 9.799 37.003 1.00 50.31 ? 556 LEU A CG 1 ATOM 3947 C CD1 . LEU A 1 530 ? -71.326 9.274 36.361 1.00 47.61 ? 556 LEU A CD1 1 ATOM 3948 C CD2 . LEU A 1 530 ? -72.570 9.583 38.503 1.00 53.55 ? 556 LEU A CD2 1 ATOM 3949 N N . GLU A 1 531 ? -74.536 10.211 34.094 1.00 53.96 ? 557 GLU A N 1 ATOM 3950 C CA . GLU A 1 531 ? -75.869 9.725 33.680 1.00 58.86 ? 557 GLU A CA 1 ATOM 3951 C C . GLU A 1 531 ? -76.088 8.296 34.112 1.00 54.01 ? 557 GLU A C 1 ATOM 3952 O O . GLU A 1 531 ? -77.221 7.885 34.369 1.00 52.25 ? 557 GLU A O 1 ATOM 3953 C CB . GLU A 1 531 ? -76.102 9.867 32.171 1.00 60.65 ? 557 GLU A CB 1 ATOM 3954 C CG . GLU A 1 531 ? -76.088 11.310 31.647 1.00 66.70 ? 557 GLU A CG 1 ATOM 3955 C CD . GLU A 1 531 ? -76.280 11.397 30.132 1.00 66.57 ? 557 GLU A CD 1 ATOM 3956 O OE1 . GLU A 1 531 ? -76.942 10.507 29.569 1.00 65.06 ? 557 GLU A OE1 1 ATOM 3957 O OE2 . GLU A 1 531 ? -75.770 12.352 29.504 1.00 65.20 ? 557 GLU A OE2 1 ATOM 3958 N N . VAL A 1 532 ? -75.015 7.522 34.167 1.00 50.88 ? 558 VAL A N 1 ATOM 3959 C CA . VAL A 1 532 ? -75.131 6.147 34.610 1.00 50.52 ? 558 VAL A CA 1 ATOM 3960 C C . VAL A 1 532 ? -74.063 5.846 35.670 1.00 52.13 ? 558 VAL A C 1 ATOM 3961 O O . VAL A 1 532 ? -72.838 5.995 35.435 1.00 47.87 ? 558 VAL A O 1 ATOM 3962 C CB . VAL A 1 532 ? -74.966 5.144 33.463 1.00 51.46 ? 558 VAL A CB 1 ATOM 3963 C CG1 . VAL A 1 532 ? -75.170 3.744 33.979 1.00 47.79 ? 558 VAL A CG1 1 ATOM 3964 C CG2 . VAL A 1 532 ? -75.945 5.417 32.348 1.00 47.18 ? 558 VAL A CG2 1 ATOM 3965 N N . LEU A 1 533 ? -74.540 5.386 36.818 1.00 47.67 ? 559 LEU A N 1 ATOM 3966 C CA . LEU A 1 533 ? -73.687 5.034 37.939 1.00 43.50 ? 559 LEU A CA 1 ATOM 3967 C C . LEU A 1 533 ? -74.002 3.628 38.380 1.00 47.98 ? 559 LEU A C 1 ATOM 3968 O O . LEU A 1 533 ? -75.134 3.331 38.798 1.00 50.60 ? 559 LEU A O 1 ATOM 3969 C CB . LEU A 1 533 ? -73.943 5.975 39.131 1.00 42.94 ? 559 LEU A CB 1 ATOM 3970 C CG . LEU A 1 533 ? -73.118 5.739 40.400 1.00 42.97 ? 559 LEU A CG 1 ATOM 3971 C CD1 . LEU A 1 533 ? -71.623 5.746 40.131 1.00 46.98 ? 559 LEU A CD1 1 ATOM 3972 C CD2 . LEU A 1 533 ? -73.441 6.772 41.432 1.00 45.69 ? 559 LEU A CD2 1 ATOM 3973 N N . ASP A 1 534 ? -73.009 2.757 38.309 1.00 46.47 ? 560 ASP A N 1 ATOM 3974 C CA . ASP A 1 534 ? -73.203 1.397 38.752 1.00 42.67 ? 560 ASP A CA 1 ATOM 3975 C C . ASP A 1 534 ? -72.350 1.141 40.031 1.00 44.24 ? 560 ASP A C 1 ATOM 3976 O O . ASP A 1 534 ? -71.110 1.153 39.961 1.00 46.63 ? 560 ASP A O 1 ATOM 3977 C CB . ASP A 1 534 ? -72.804 0.431 37.661 1.00 41.70 ? 560 ASP A CB 1 ATOM 3978 C CG . ASP A 1 534 ? -73.242 -1.006 37.969 1.00 47.80 ? 560 ASP A CG 1 ATOM 3979 O OD1 . ASP A 1 534 ? -73.898 -1.200 39.022 1.00 48.23 ? 560 ASP A OD1 1 ATOM 3980 O OD2 . ASP A 1 534 ? -73.030 -1.906 37.110 1.00 49.66 ? 560 ASP A OD2 1 ATOM 3981 N N . LEU A 1 535 ? -73.025 0.978 41.178 1.00 41.35 ? 561 LEU A N 1 ATOM 3982 C CA . LEU A 1 535 ? -72.371 0.703 42.476 1.00 47.85 ? 561 LEU A CA 1 ATOM 3983 C C . LEU A 1 535 ? -72.630 -0.730 42.966 1.00 53.24 ? 561 LEU A C 1 ATOM 3984 O O . LEU A 1 535 ? -72.568 -0.995 44.157 1.00 53.12 ? 561 LEU A O 1 ATOM 3985 C CB . LEU A 1 535 ? -72.897 1.629 43.564 1.00 44.29 ? 561 LEU A CB 1 ATOM 3986 C CG . LEU A 1 535 ? -72.805 3.128 43.320 1.00 52.18 ? 561 LEU A CG 1 ATOM 3987 C CD1 . LEU A 1 535 ? -73.463 3.923 44.456 1.00 47.03 ? 561 LEU A CD1 1 ATOM 3988 C CD2 . LEU A 1 535 ? -71.343 3.517 43.151 1.00 52.75 ? 561 LEU A CD2 1 ATOM 3989 N N . SER A 1 536 ? -73.021 -1.618 42.069 1.00 48.75 ? 562 SER A N 1 ATOM 3990 C CA . SER A 1 536 ? -73.274 -2.986 42.436 1.00 46.38 ? 562 SER A CA 1 ATOM 3991 C C . SER A 1 536 ? -72.111 -3.668 43.116 1.00 43.17 ? 562 SER A C 1 ATOM 3992 O O . SER A 1 536 ? -70.975 -3.430 42.779 1.00 46.10 ? 562 SER A O 1 ATOM 3993 C CB . SER A 1 536 ? -73.616 -3.815 41.199 1.00 46.08 ? 562 SER A CB 1 ATOM 3994 O OG . SER A 1 536 ? -74.832 -3.372 40.659 1.00 59.14 ? 562 SER A OG 1 ATOM 3995 N N . TYR A 1 537 ? -72.438 -4.611 44.000 1.00 45.18 ? 563 TYR A N 1 ATOM 3996 C CA . TYR A 1 537 ? -71.466 -5.414 44.717 1.00 42.95 ? 563 TYR A CA 1 ATOM 3997 C C . TYR A 1 537 ? -70.420 -4.674 45.519 1.00 45.08 ? 563 TYR A C 1 ATOM 3998 O O . TYR A 1 537 ? -69.209 -4.824 45.295 1.00 39.54 ? 563 TYR A O 1 ATOM 3999 C CB . TYR A 1 537 ? -70.794 -6.405 43.774 1.00 48.04 ? 563 TYR A CB 1 ATOM 4000 C CG . TYR A 1 537 ? -71.757 -7.393 43.181 1.00 50.99 ? 563 TYR A CG 1 ATOM 4001 C CD1 . TYR A 1 537 ? -72.112 -8.543 43.879 1.00 50.23 ? 563 TYR A CD1 1 ATOM 4002 C CD2 . TYR A 1 537 ? -72.307 -7.196 41.911 1.00 58.73 ? 563 TYR A CD2 1 ATOM 4003 C CE1 . TYR A 1 537 ? -73.033 -9.444 43.364 1.00 51.88 ? 563 TYR A CE1 1 ATOM 4004 C CE2 . TYR A 1 537 ? -73.192 -8.117 41.369 1.00 58.08 ? 563 TYR A CE2 1 ATOM 4005 C CZ . TYR A 1 537 ? -73.551 -9.234 42.104 1.00 56.72 ? 563 TYR A CZ 1 ATOM 4006 O OH . TYR A 1 537 ? -74.447 -10.121 41.579 1.00 70.24 ? 563 TYR A OH 1 ATOM 4007 N N . ASN A 1 538 ? -70.914 -3.838 46.413 1.00 44.61 ? 564 ASN A N 1 ATOM 4008 C CA . ASN A 1 538 ? -70.108 -3.074 47.367 1.00 48.56 ? 564 ASN A CA 1 ATOM 4009 C C . ASN A 1 538 ? -70.771 -3.263 48.721 1.00 50.66 ? 564 ASN A C 1 ATOM 4010 O O . ASN A 1 538 ? -70.944 -2.316 49.484 1.00 49.86 ? 564 ASN A O 1 ATOM 4011 C CB . ASN A 1 538 ? -70.011 -1.598 46.988 1.00 46.40 ? 564 ASN A CB 1 ATOM 4012 C CG . ASN A 1 538 ? -68.974 -1.352 45.927 1.00 47.55 ? 564 ASN A CG 1 ATOM 4013 O OD1 . ASN A 1 538 ? -67.775 -1.463 46.190 1.00 47.22 ? 564 ASN A OD1 1 ATOM 4014 N ND2 . ASN A 1 538 ? -69.408 -0.890 44.776 1.00 46.11 ? 564 ASN A ND2 1 ATOM 4015 N N . SER A 1 539 ? -71.145 -4.508 49.009 1.00 48.43 ? 565 SER A N 1 ATOM 4016 C CA . SER A 1 539 ? -71.836 -4.827 50.275 1.00 52.59 ? 565 SER A CA 1 ATOM 4017 C C . SER A 1 539 ? -70.994 -4.708 51.540 1.00 48.98 ? 565 SER A C 1 ATOM 4018 O O . SER A 1 539 ? -71.511 -4.287 52.568 1.00 47.90 ? 565 SER A O 1 ATOM 4019 C CB . SER A 1 539 ? -72.383 -6.237 50.205 1.00 43.58 ? 565 SER A CB 1 ATOM 4020 O OG . SER A 1 539 ? -71.345 -7.068 49.733 1.00 55.38 ? 565 SER A OG 1 ATOM 4021 N N . HIS A 1 540 ? -69.687 -4.800 51.462 1.00 44.11 ? 566 HIS A N 1 ATOM 4022 C CA . HIS A 1 540 ? -68.897 -5.010 52.637 1.00 48.72 ? 566 HIS A CA 1 ATOM 4023 C C . HIS A 1 540 ? -69.100 -4.015 53.742 1.00 48.15 ? 566 HIS A C 1 ATOM 4024 O O . HIS A 1 540 ? -69.307 -4.442 54.858 1.00 53.48 ? 566 HIS A O 1 ATOM 4025 C CB . HIS A 1 540 ? -67.437 -5.024 52.221 1.00 49.79 ? 566 HIS A CB 1 ATOM 4026 C CG . HIS A 1 540 ? -66.463 -5.024 53.360 1.00 63.78 ? 566 HIS A CG 1 ATOM 4027 N ND1 . HIS A 1 540 ? -65.938 -6.126 53.851 1.00 63.55 ? 566 HIS A ND1 1 ATOM 4028 C CD2 . HIS A 1 540 ? -65.927 -3.989 54.080 1.00 68.92 ? 566 HIS A CD2 1 ATOM 4029 C CE1 . HIS A 1 540 ? -65.117 -5.820 54.844 1.00 58.46 ? 566 HIS A CE1 1 ATOM 4030 N NE2 . HIS A 1 540 ? -65.111 -4.513 54.980 1.00 63.91 ? 566 HIS A NE2 1 ATOM 4031 N N . TYR A 1 541 ? -69.128 -2.720 53.501 1.00 42.46 ? 567 TYR A N 1 ATOM 4032 C CA . TYR A 1 541 ? -69.447 -1.795 54.581 1.00 44.59 ? 567 TYR A CA 1 ATOM 4033 C C . TYR A 1 541 ? -70.901 -1.645 54.889 1.00 52.94 ? 567 TYR A C 1 ATOM 4034 O O . TYR A 1 541 ? -71.239 -1.111 55.954 1.00 55.25 ? 567 TYR A O 1 ATOM 4035 C CB . TYR A 1 541 ? -68.815 -0.407 54.403 1.00 42.54 ? 567 TYR A CB 1 ATOM 4036 C CG . TYR A 1 541 ? -67.326 -0.427 54.594 1.00 52.93 ? 567 TYR A CG 1 ATOM 4037 C CD1 . TYR A 1 541 ? -66.779 -0.461 55.877 1.00 56.82 ? 567 TYR A CD1 1 ATOM 4038 C CD2 . TYR A 1 541 ? -66.452 -0.393 53.508 1.00 48.70 ? 567 TYR A CD2 1 ATOM 4039 C CE1 . TYR A 1 541 ? -65.412 -0.488 56.076 1.00 48.16 ? 567 TYR A CE1 1 ATOM 4040 C CE2 . TYR A 1 541 ? -65.092 -0.437 53.701 1.00 55.91 ? 567 TYR A CE2 1 ATOM 4041 C CZ . TYR A 1 541 ? -64.581 -0.469 54.987 1.00 56.63 ? 567 TYR A CZ 1 ATOM 4042 O OH . TYR A 1 541 ? -63.228 -0.465 55.167 1.00 60.66 ? 567 TYR A OH 1 ATOM 4043 N N . PHE A 1 542 ? -71.774 -2.031 53.964 1.00 52.70 ? 568 PHE A N 1 ATOM 4044 C CA . PHE A 1 542 ? -73.215 -1.914 54.222 1.00 49.13 ? 568 PHE A CA 1 ATOM 4045 C C . PHE A 1 542 ? -73.678 -2.919 55.236 1.00 50.00 ? 568 PHE A C 1 ATOM 4046 O O . PHE A 1 542 ? -74.583 -2.636 55.999 1.00 62.03 ? 568 PHE A O 1 ATOM 4047 C CB . PHE A 1 542 ? -74.047 -2.024 52.947 1.00 51.42 ? 568 PHE A CB 1 ATOM 4048 C CG . PHE A 1 542 ? -73.997 -0.788 52.084 1.00 48.52 ? 568 PHE A CG 1 ATOM 4049 C CD1 . PHE A 1 542 ? -74.791 0.294 52.388 1.00 44.22 ? 568 PHE A CD1 1 ATOM 4050 C CD2 . PHE A 1 542 ? -73.222 -0.743 50.942 1.00 50.12 ? 568 PHE A CD2 1 ATOM 4051 C CE1 . PHE A 1 542 ? -74.763 1.425 51.618 1.00 49.26 ? 568 PHE A CE1 1 ATOM 4052 C CE2 . PHE A 1 542 ? -73.202 0.384 50.153 1.00 57.75 ? 568 PHE A CE2 1 ATOM 4053 C CZ . PHE A 1 542 ? -73.980 1.473 50.489 1.00 51.71 ? 568 PHE A CZ 1 ATOM 4054 N N . ARG A 1 543 ? -73.024 -4.073 55.260 1.00 46.85 ? 569 ARG A N 1 ATOM 4055 C CA . ARG A 1 543 ? -73.352 -5.125 56.187 1.00 56.52 ? 569 ARG A CA 1 ATOM 4056 C C . ARG A 1 543 ? -73.035 -4.861 57.679 1.00 68.06 ? 569 ARG A C 1 ATOM 4057 O O . ARG A 1 543 ? -73.762 -5.310 58.557 1.00 82.71 ? 569 ARG A O 1 ATOM 4058 C CB . ARG A 1 543 ? -72.526 -6.333 55.844 1.00 57.23 ? 569 ARG A CB 1 ATOM 4059 C CG . ARG A 1 543 ? -72.760 -6.919 54.501 1.00 62.41 ? 569 ARG A CG 1 ATOM 4060 C CD . ARG A 1 543 ? -71.872 -8.138 54.341 1.00 70.73 ? 569 ARG A CD 1 ATOM 4061 N NE . ARG A 1 543 ? -72.110 -8.731 53.042 1.00 88.10 ? 569 ARG A NE 1 ATOM 4062 C CZ . ARG A 1 543 ? -73.132 -9.537 52.788 1.00 94.47 ? 569 ARG A CZ 1 ATOM 4063 N NH1 . ARG A 1 543 ? -74.012 -9.809 53.745 1.00 78.79 ? 569 ARG A NH1 1 ATOM 4064 N NH2 . ARG A 1 543 ? -73.296 -10.040 51.573 1.00 117.45 ? 569 ARG A NH2 1 ATOM 4065 N N . ILE A 1 544 ? -71.932 -4.167 57.937 1.00 72.78 ? 570 ILE A N 1 ATOM 4066 C CA . ILE A 1 544 ? -71.423 -3.891 59.298 1.00 58.42 ? 570 ILE A CA 1 ATOM 4067 C C . ILE A 1 544 ? -72.179 -2.923 60.206 1.00 55.10 ? 570 ILE A C 1 ATOM 4068 O O . ILE A 1 544 ? -72.333 -1.761 59.907 1.00 64.74 ? 570 ILE A O 1 ATOM 4069 C CB . ILE A 1 544 ? -69.984 -3.424 59.193 1.00 56.10 ? 570 ILE A CB 1 ATOM 4070 C CG1 . ILE A 1 544 ? -69.181 -4.464 58.401 1.00 49.83 ? 570 ILE A CG1 1 ATOM 4071 C CG2 . ILE A 1 544 ? -69.420 -3.192 60.586 1.00 57.86 ? 570 ILE A CG2 1 ATOM 4072 C CD1 . ILE A 1 544 ? -67.792 -4.019 58.022 1.00 48.89 ? 570 ILE A CD1 1 ATOM 4073 N N . ALA A 1 545 ? -72.645 -3.415 61.345 1.00 51.52 ? 571 ALA A N 1 ATOM 4074 C CA . ALA A 1 545 ? -73.377 -2.556 62.268 1.00 56.63 ? 571 ALA A CA 1 ATOM 4075 C C . ALA A 1 545 ? -72.482 -1.453 62.824 1.00 61.66 ? 571 ALA A C 1 ATOM 4076 O O . ALA A 1 545 ? -71.292 -1.680 63.088 1.00 67.70 ? 571 ALA A O 1 ATOM 4077 C CB . ALA A 1 545 ? -73.946 -3.384 63.402 1.00 64.82 ? 571 ALA A CB 1 ATOM 4078 N N . GLY A 1 546 ? -73.025 -0.241 62.933 1.00 61.38 ? 572 GLY A N 1 ATOM 4079 C CA . GLY A 1 546 ? -72.262 0.881 63.487 1.00 70.82 ? 572 GLY A CA 1 ATOM 4080 C C . GLY A 1 546 ? -71.626 1.777 62.468 1.00 69.02 ? 572 GLY A C 1 ATOM 4081 O O . GLY A 1 546 ? -71.327 2.941 62.760 1.00 75.70 ? 572 GLY A O 1 ATOM 4082 N N . VAL A 1 547 ? -71.277 1.207 61.319 1.00 65.74 ? 573 VAL A N 1 ATOM 4083 C CA . VAL A 1 547 ? -70.722 2.016 60.272 1.00 62.02 ? 573 VAL A CA 1 ATOM 4084 C C . VAL A 1 547 ? -71.873 2.796 59.655 1.00 57.65 ? 573 VAL A C 1 ATOM 4085 O O . VAL A 1 547 ? -72.988 2.325 59.585 1.00 66.08 ? 573 VAL A O 1 ATOM 4086 C CB . VAL A 1 547 ? -69.863 1.239 59.257 1.00 68.24 ? 573 VAL A CB 1 ATOM 4087 C CG1 . VAL A 1 547 ? -70.335 -0.162 59.069 1.00 80.11 ? 573 VAL A CG1 1 ATOM 4088 C CG2 . VAL A 1 547 ? -69.768 2.001 57.937 1.00 74.36 ? 573 VAL A CG2 1 ATOM 4089 N N . THR A 1 548 ? -71.630 4.067 59.423 1.00 55.54 ? 574 THR A N 1 ATOM 4090 C CA . THR A 1 548 ? -72.612 4.952 58.855 1.00 54.59 ? 574 THR A CA 1 ATOM 4091 C C . THR A 1 548 ? -72.648 4.933 57.313 1.00 54.76 ? 574 THR A C 1 ATOM 4092 O O . THR A 1 548 ? -71.624 4.776 56.634 1.00 59.98 ? 574 THR A O 1 ATOM 4093 C CB . THR A 1 548 ? -72.359 6.353 59.388 1.00 59.42 ? 574 THR A CB 1 ATOM 4094 O OG1 . THR A 1 548 ? -70.960 6.662 59.231 1.00 53.28 ? 574 THR A OG1 1 ATOM 4095 C CG2 . THR A 1 548 ? -72.732 6.400 60.874 1.00 53.65 ? 574 THR A CG2 1 ATOM 4096 N N . HIS A 1 549 ? -73.831 5.154 56.767 1.00 54.74 ? 575 HIS A N 1 ATOM 4097 C CA . HIS A 1 549 ? -74.013 5.104 55.313 1.00 52.88 ? 575 HIS A CA 1 ATOM 4098 C C . HIS A 1 549 ? -74.761 6.304 54.796 1.00 54.75 ? 575 HIS A C 1 ATOM 4099 O O . HIS A 1 549 ? -75.895 6.559 55.202 1.00 63.23 ? 575 HIS A O 1 ATOM 4100 C CB . HIS A 1 549 ? -74.812 3.871 55.005 1.00 55.21 ? 575 HIS A CB 1 ATOM 4101 C CG . HIS A 1 549 ? -74.382 2.681 55.803 1.00 52.40 ? 575 HIS A CG 1 ATOM 4102 N ND1 . HIS A 1 549 ? -73.263 1.940 55.495 1.00 48.64 ? 575 HIS A ND1 1 ATOM 4103 C CD2 . HIS A 1 549 ? -74.928 2.105 56.899 1.00 53.59 ? 575 HIS A CD2 1 ATOM 4104 C CE1 . HIS A 1 549 ? -73.154 0.940 56.351 1.00 56.70 ? 575 HIS A CE1 1 ATOM 4105 N NE2 . HIS A 1 549 ? -74.153 1.014 57.213 1.00 54.63 ? 575 HIS A NE2 1 ATOM 4106 N N . HIS A 1 550 ? -74.124 7.029 53.889 1.00 54.41 ? 576 HIS A N 1 ATOM 4107 C CA . HIS A 1 550 ? -74.692 8.216 53.311 1.00 56.99 ? 576 HIS A CA 1 ATOM 4108 C C . HIS A 1 550 ? -74.863 8.142 51.791 1.00 57.90 ? 576 HIS A C 1 ATOM 4109 O O . HIS A 1 550 ? -73.886 8.166 51.035 1.00 60.12 ? 576 HIS A O 1 ATOM 4110 C CB . HIS A 1 550 ? -73.808 9.406 53.673 1.00 62.02 ? 576 HIS A CB 1 ATOM 4111 C CG . HIS A 1 550 ? -73.762 9.706 55.147 1.00 66.43 ? 576 HIS A CG 1 ATOM 4112 N ND1 . HIS A 1 550 ? -74.681 10.518 55.769 1.00 69.36 ? 576 HIS A ND1 1 ATOM 4113 C CD2 . HIS A 1 550 ? -72.858 9.373 56.097 1.00 65.35 ? 576 HIS A CD2 1 ATOM 4114 C CE1 . HIS A 1 550 ? -74.378 10.630 57.047 1.00 65.55 ? 576 HIS A CE1 1 ATOM 4115 N NE2 . HIS A 1 550 ? -73.274 9.948 57.270 1.00 65.57 ? 576 HIS A NE2 1 ATOM 4116 N N . LEU A 1 551 ? -76.117 8.106 51.350 1.00 67.73 ? 577 LEU A N 1 ATOM 4117 C CA . LEU A 1 551 ? -76.444 8.066 49.907 1.00 67.11 ? 577 LEU A CA 1 ATOM 4118 C C . LEU A 1 551 ? -77.084 9.373 49.414 1.00 67.24 ? 577 LEU A C 1 ATOM 4119 O O . LEU A 1 551 ? -77.652 9.420 48.325 1.00 65.62 ? 577 LEU A O 1 ATOM 4120 C CB . LEU A 1 551 ? -77.363 6.872 49.575 1.00 55.93 ? 577 LEU A CB 1 ATOM 4121 C CG . LEU A 1 551 ? -76.716 5.508 49.825 1.00 58.20 ? 577 LEU A CG 1 ATOM 4122 C CD1 . LEU A 1 551 ? -77.649 4.409 49.385 1.00 61.31 ? 577 LEU A CD1 1 ATOM 4123 C CD2 . LEU A 1 551 ? -75.399 5.360 49.083 1.00 63.98 ? 577 LEU A CD2 1 ATOM 4124 N N . GLU A 1 552 ? -76.912 10.440 50.189 1.00 72.33 ? 578 GLU A N 1 ATOM 4125 C CA . GLU A 1 552 ? -77.483 11.732 49.862 1.00 66.29 ? 578 GLU A CA 1 ATOM 4126 C C . GLU A 1 552 ? -76.979 12.298 48.549 1.00 67.77 ? 578 GLU A C 1 ATOM 4127 O O . GLU A 1 552 ? -77.649 13.157 47.971 1.00 72.40 ? 578 GLU A O 1 ATOM 4128 C CB . GLU A 1 552 ? -77.178 12.800 50.924 1.00 68.67 ? 578 GLU A CB 1 ATOM 4129 C CG . GLU A 1 552 ? -77.649 12.579 52.352 1.00 80.26 ? 578 GLU A CG 1 ATOM 4130 C CD . GLU A 1 552 ? -76.762 11.664 53.183 1.00 82.07 ? 578 GLU A CD 1 ATOM 4131 O OE1 . GLU A 1 552 ? -75.910 10.964 52.621 1.00 77.08 ? 578 GLU A OE1 1 ATOM 4132 O OE2 . GLU A 1 552 ? -76.915 11.673 54.423 1.00 81.12 ? 578 GLU A OE2 1 ATOM 4133 N N . PHE A 1 553 ? -75.772 11.902 48.126 1.00 54.68 ? 579 PHE A N 1 ATOM 4134 C CA . PHE A 1 553 ? -75.191 12.432 46.879 1.00 54.94 ? 579 PHE A CA 1 ATOM 4135 C C . PHE A 1 553 ? -76.049 12.209 45.637 1.00 59.31 ? 579 PHE A C 1 ATOM 4136 O O . PHE A 1 553 ? -75.920 12.921 44.642 1.00 67.68 ? 579 PHE A O 1 ATOM 4137 C CB . PHE A 1 553 ? -73.772 11.893 46.649 1.00 58.90 ? 579 PHE A CB 1 ATOM 4138 C CG . PHE A 1 553 ? -73.698 10.401 46.531 1.00 60.24 ? 579 PHE A CG 1 ATOM 4139 C CD1 . PHE A 1 553 ? -73.864 9.786 45.315 1.00 66.65 ? 579 PHE A CD1 1 ATOM 4140 C CD2 . PHE A 1 553 ? -73.402 9.630 47.620 1.00 61.46 ? 579 PHE A CD2 1 ATOM 4141 C CE1 . PHE A 1 553 ? -73.800 8.417 45.205 1.00 64.44 ? 579 PHE A CE1 1 ATOM 4142 C CE2 . PHE A 1 553 ? -73.353 8.260 47.523 1.00 58.78 ? 579 PHE A CE2 1 ATOM 4143 C CZ . PHE A 1 553 ? -73.544 7.656 46.316 1.00 63.56 ? 579 PHE A CZ 1 ATOM 4144 N N . ILE A 1 554 ? -76.939 11.237 45.710 1.00 57.21 ? 580 ILE A N 1 ATOM 4145 C CA . ILE A 1 554 ? -77.810 10.912 44.610 1.00 60.20 ? 580 ILE A CA 1 ATOM 4146 C C . ILE A 1 554 ? -78.556 12.130 44.082 1.00 65.84 ? 580 ILE A C 1 ATOM 4147 O O . ILE A 1 554 ? -78.538 12.394 42.881 1.00 62.89 ? 580 ILE A O 1 ATOM 4148 C CB . ILE A 1 554 ? -78.777 9.803 45.021 1.00 62.86 ? 580 ILE A CB 1 ATOM 4149 C CG1 . ILE A 1 554 ? -77.987 8.504 45.194 1.00 69.54 ? 580 ILE A CG1 1 ATOM 4150 C CG2 . ILE A 1 554 ? -79.834 9.599 43.969 1.00 62.17 ? 580 ILE A CG2 1 ATOM 4151 C CD1 . ILE A 1 554 ? -78.813 7.340 45.679 1.00 75.67 ? 580 ILE A CD1 1 ATOM 4152 N N . GLN A 1 555 ? -79.138 12.912 44.984 1.00 62.51 ? 581 GLN A N 1 ATOM 4153 C CA . GLN A 1 555 ? -79.889 14.094 44.585 1.00 61.63 ? 581 GLN A CA 1 ATOM 4154 C C . GLN A 1 555 ? -79.100 15.207 43.933 1.00 65.73 ? 581 GLN A C 1 ATOM 4155 O O . GLN A 1 555 ? -79.656 15.952 43.148 1.00 79.35 ? 581 GLN A O 1 ATOM 4156 C CB . GLN A 1 555 ? -80.707 14.652 45.726 1.00 65.58 ? 581 GLN A CB 1 ATOM 4157 C CG . GLN A 1 555 ? -79.957 14.752 47.035 1.00 91.10 ? 581 GLN A CG 1 ATOM 4158 C CD . GLN A 1 555 ? -80.694 15.591 48.050 1.00 100.94 ? 581 GLN A CD 1 ATOM 4159 O OE1 . GLN A 1 555 ? -81.293 15.061 48.984 1.00 102.39 ? 581 GLN A OE1 1 ATOM 4160 N NE2 . GLN A 1 555 ? -80.815 16.878 47.762 1.00 105.80 ? 581 GLN A NE2 1 ATOM 4161 N N . ASN A 1 556 ? -77.804 15.280 44.169 1.00 66.74 ? 582 ASN A N 1 ATOM 4162 C CA . ASN A 1 556 ? -77.003 16.352 43.571 1.00 70.84 ? 582 ASN A CA 1 ATOM 4163 C C . ASN A 1 556 ? -76.786 16.300 42.089 1.00 65.82 ? 582 ASN A C 1 ATOM 4164 O O . ASN A 1 556 ? -76.195 17.211 41.552 1.00 90.44 ? 582 ASN A O 1 ATOM 4165 C CB . ASN A 1 556 ? -75.623 16.449 44.238 1.00 76.35 ? 582 ASN A CB 1 ATOM 4166 C CG . ASN A 1 556 ? -75.685 16.996 45.653 1.00 98.96 ? 582 ASN A CG 1 ATOM 4167 O OD1 . ASN A 1 556 ? -75.177 16.378 46.595 1.00 126.84 ? 582 ASN A OD1 1 ATOM 4168 N ND2 . ASN A 1 556 ? -76.346 18.135 45.823 1.00 101.68 ? 582 ASN A ND2 1 ATOM 4169 N N . PHE A 1 557 ? -77.178 15.226 41.424 1.00 71.09 ? 583 PHE A N 1 ATOM 4170 C CA . PHE A 1 557 ? -76.947 15.141 39.978 1.00 68.36 ? 583 PHE A CA 1 ATOM 4171 C C . PHE A 1 557 ? -78.182 15.618 39.253 1.00 71.39 ? 583 PHE A C 1 ATOM 4172 O O . PHE A 1 557 ? -79.293 15.249 39.608 1.00 71.61 ? 583 PHE A O 1 ATOM 4173 C CB . PHE A 1 557 ? -76.634 13.711 39.539 1.00 65.37 ? 583 PHE A CB 1 ATOM 4174 C CG . PHE A 1 557 ? -75.475 13.107 40.246 1.00 57.97 ? 583 PHE A CG 1 ATOM 4175 C CD1 . PHE A 1 557 ? -74.194 13.385 39.853 1.00 56.43 ? 583 PHE A CD1 1 ATOM 4176 C CD2 . PHE A 1 557 ? -75.672 12.192 41.246 1.00 65.05 ? 583 PHE A CD2 1 ATOM 4177 C CE1 . PHE A 1 557 ? -73.117 12.830 40.507 1.00 56.54 ? 583 PHE A CE1 1 ATOM 4178 C CE2 . PHE A 1 557 ? -74.596 11.618 41.899 1.00 66.02 ? 583 PHE A CE2 1 ATOM 4179 C CZ . PHE A 1 557 ? -73.321 11.942 41.531 1.00 60.10 ? 583 PHE A CZ 1 ATOM 4180 N N . THR A 1 558 ? -77.990 16.418 38.218 1.00 60.79 ? 584 THR A N 1 ATOM 4181 C CA . THR A 1 558 ? -79.116 16.929 37.473 1.00 65.19 ? 584 THR A CA 1 ATOM 4182 C C . THR A 1 558 ? -79.422 16.063 36.283 1.00 60.30 ? 584 THR A C 1 ATOM 4183 O O . THR A 1 558 ? -80.559 15.984 35.862 1.00 63.76 ? 584 THR A O 1 ATOM 4184 C CB . THR A 1 558 ? -78.844 18.348 36.919 1.00 71.17 ? 584 THR A CB 1 ATOM 4185 O OG1 . THR A 1 558 ? -77.775 18.307 35.960 1.00 71.68 ? 584 THR A OG1 1 ATOM 4186 C CG2 . THR A 1 558 ? -78.489 19.308 38.028 1.00 72.55 ? 584 THR A CG2 1 ATOM 4187 N N . ASN A 1 559 ? -78.431 15.332 35.795 1.00 65.95 ? 585 ASN A N 1 ATOM 4188 C CA . ASN A 1 559 ? -78.642 14.528 34.604 1.00 67.65 ? 585 ASN A CA 1 ATOM 4189 C C . ASN A 1 559 ? -78.435 13.007 34.834 1.00 60.18 ? 585 ASN A C 1 ATOM 4190 O O . ASN A 1 559 ? -78.148 12.266 33.907 1.00 58.97 ? 585 ASN A O 1 ATOM 4191 C CB . ASN A 1 559 ? -77.689 15.085 33.531 1.00 68.34 ? 585 ASN A CB 1 ATOM 4192 C CG . ASN A 1 559 ? -78.055 14.659 32.124 1.00 91.66 ? 585 ASN A CG 1 ATOM 4193 O OD1 . ASN A 1 559 ? -79.243 14.600 31.759 1.00 71.55 ? 585 ASN A OD1 1 ATOM 4194 N ND2 . ASN A 1 559 ? -77.030 14.480 31.281 1.00 100.94 ? 585 ASN A ND2 1 ATOM 4195 N N . LEU A 1 560 ? -78.616 12.541 36.068 1.00 62.66 ? 586 LEU A N 1 ATOM 4196 C CA . LEU A 1 560 ? -78.427 11.118 36.392 1.00 56.03 ? 586 LEU A CA 1 ATOM 4197 C C . LEU A 1 560 ? -79.667 10.345 35.966 1.00 55.29 ? 586 LEU A C 1 ATOM 4198 O O . LEU A 1 560 ? -80.763 10.615 36.476 1.00 56.67 ? 586 LEU A O 1 ATOM 4199 C CB . LEU A 1 560 ? -78.185 10.932 37.893 1.00 54.34 ? 586 LEU A CB 1 ATOM 4200 C CG . LEU A 1 560 ? -78.006 9.486 38.382 1.00 53.87 ? 586 LEU A CG 1 ATOM 4201 C CD1 . LEU A 1 560 ? -76.755 8.864 37.777 1.00 54.80 ? 586 LEU A CD1 1 ATOM 4202 C CD2 . LEU A 1 560 ? -77.921 9.416 39.899 1.00 54.16 ? 586 LEU A CD2 1 ATOM 4203 N N . LYS A 1 561 ? -79.484 9.307 35.144 1.00 46.98 ? 587 LYS A N 1 ATOM 4204 C CA . LYS A 1 561 ? -80.629 8.528 34.639 1.00 53.75 ? 587 LYS A CA 1 ATOM 4205 C C . LYS A 1 561 ? -80.798 7.120 35.193 1.00 58.00 ? 587 LYS A C 1 ATOM 4206 O O . LYS A 1 561 ? -81.928 6.687 35.457 1.00 61.11 ? 587 LYS A O 1 ATOM 4207 C CB . LYS A 1 561 ? -80.535 8.427 33.113 1.00 50.27 ? 587 LYS A CB 1 ATOM 4208 C CG . LYS A 1 561 ? -80.510 9.774 32.423 1.00 60.79 ? 587 LYS A CG 1 ATOM 4209 C CD . LYS A 1 561 ? -80.204 9.671 30.935 1.00 69.27 ? 587 LYS A CD 1 ATOM 4210 C CE . LYS A 1 561 ? -80.073 11.058 30.311 1.00 78.42 ? 587 LYS A CE 1 ATOM 4211 N NZ . LYS A 1 561 ? -79.669 10.988 28.885 1.00 84.62 ? 587 LYS A NZ 1 ATOM 4212 N N . VAL A 1 562 ? -79.680 6.415 35.349 1.00 52.70 ? 588 VAL A N 1 ATOM 4213 C CA . VAL A 1 562 ? -79.668 5.027 35.822 1.00 51.98 ? 588 VAL A CA 1 ATOM 4214 C C . VAL A 1 562 ? -78.726 4.800 37.005 1.00 55.77 ? 588 VAL A C 1 ATOM 4215 O O . VAL A 1 562 ? -77.519 5.063 36.935 1.00 58.44 ? 588 VAL A O 1 ATOM 4216 C CB . VAL A 1 562 ? -79.170 4.133 34.685 1.00 52.03 ? 588 VAL A CB 1 ATOM 4217 C CG1 . VAL A 1 562 ? -79.126 2.685 35.102 1.00 51.78 ? 588 VAL A CG1 1 ATOM 4218 C CG2 . VAL A 1 562 ? -80.051 4.300 33.474 1.00 52.98 ? 588 VAL A CG2 1 ATOM 4219 N N . LEU A 1 563 ? -79.261 4.215 38.051 1.00 51.75 ? 589 LEU A N 1 ATOM 4220 C CA . LEU A 1 563 ? -78.481 3.946 39.236 1.00 53.61 ? 589 LEU A CA 1 ATOM 4221 C C . LEU A 1 563 ? -78.686 2.504 39.646 1.00 49.75 ? 589 LEU A C 1 ATOM 4222 O O . LEU A 1 563 ? -79.824 2.044 39.821 1.00 50.44 ? 589 LEU A O 1 ATOM 4223 C CB . LEU A 1 563 ? -78.937 4.875 40.366 1.00 52.44 ? 589 LEU A CB 1 ATOM 4224 C CG . LEU A 1 563 ? -78.302 4.697 41.748 1.00 55.10 ? 589 LEU A CG 1 ATOM 4225 C CD1 . LEU A 1 563 ? -76.796 4.904 41.709 1.00 51.76 ? 589 LEU A CD1 1 ATOM 4226 C CD2 . LEU A 1 563 ? -78.931 5.654 42.757 1.00 52.67 ? 589 LEU A CD2 1 ATOM 4227 N N . ASN A 1 564 ? -77.593 1.783 39.798 1.00 44.32 ? 590 ASN A N 1 ATOM 4228 C CA . ASN A 1 564 ? -77.676 0.392 40.207 1.00 41.28 ? 590 ASN A CA 1 ATOM 4229 C C . ASN A 1 564 ? -76.954 0.217 41.550 1.00 48.68 ? 590 ASN A C 1 ATOM 4230 O O . ASN A 1 564 ? -75.725 0.399 41.633 1.00 47.54 ? 590 ASN A O 1 ATOM 4231 C CB . ASN A 1 564 ? -77.054 -0.486 39.134 1.00 40.67 ? 590 ASN A CB 1 ATOM 4232 C CG . ASN A 1 564 ? -77.244 -1.967 39.391 1.00 41.26 ? 590 ASN A CG 1 ATOM 4233 O OD1 . ASN A 1 564 ? -77.517 -2.377 40.500 1.00 49.08 ? 590 ASN A OD1 1 ATOM 4234 N ND2 . ASN A 1 564 ? -77.065 -2.781 38.367 1.00 46.74 ? 590 ASN A ND2 1 ATOM 4235 N N . LEU A 1 565 ? -77.745 -0.070 42.593 1.00 43.14 ? 591 LEU A N 1 ATOM 4236 C CA . LEU A 1 565 ? -77.267 -0.317 43.964 1.00 39.65 ? 591 LEU A CA 1 ATOM 4237 C C . LEU A 1 565 ? -77.496 -1.803 44.298 1.00 43.59 ? 591 LEU A C 1 ATOM 4238 O O . LEU A 1 565 ? -77.697 -2.165 45.456 1.00 46.05 ? 591 LEU A O 1 ATOM 4239 C CB . LEU A 1 565 ? -78.096 0.474 44.962 1.00 38.28 ? 591 LEU A CB 1 ATOM 4240 C CG . LEU A 1 565 ? -78.111 1.985 44.806 1.00 46.46 ? 591 LEU A CG 1 ATOM 4241 C CD1 . LEU A 1 565 ? -79.052 2.624 45.811 1.00 46.91 ? 591 LEU A CD1 1 ATOM 4242 C CD2 . LEU A 1 565 ? -76.709 2.530 44.969 1.00 53.48 ? 591 LEU A CD2 1 ATOM 4243 N N . SER A 1 566 ? -77.523 -2.665 43.299 1.00 43.09 ? 592 SER A N 1 ATOM 4244 C CA . SER A 1 566 ? -77.782 -4.075 43.579 1.00 49.49 ? 592 SER A CA 1 ATOM 4245 C C . SER A 1 566 ? -76.659 -4.788 44.345 1.00 51.04 ? 592 SER A C 1 ATOM 4246 O O . SER A 1 566 ? -75.485 -4.461 44.210 1.00 51.89 ? 592 SER A O 1 ATOM 4247 C CB . SER A 1 566 ? -78.036 -4.864 42.286 1.00 48.29 ? 592 SER A CB 1 ATOM 4248 O OG . SER A 1 566 ? -76.856 -4.958 41.507 1.00 49.13 ? 592 SER A OG 1 ATOM 4249 N N . HIS A 1 567 ? -77.059 -5.793 45.117 1.00 44.85 ? 593 HIS A N 1 ATOM 4250 C CA . HIS A 1 567 ? -76.151 -6.643 45.893 1.00 44.44 ? 593 HIS A CA 1 ATOM 4251 C C . HIS A 1 567 ? -75.201 -5.927 46.863 1.00 43.92 ? 593 HIS A C 1 ATOM 4252 O O . HIS A 1 567 ? -74.053 -6.310 46.998 1.00 41.65 ? 593 HIS A O 1 ATOM 4253 C CB . HIS A 1 567 ? -75.385 -7.567 44.968 1.00 43.71 ? 593 HIS A CB 1 ATOM 4254 C CG . HIS A 1 567 ? -76.268 -8.345 44.050 1.00 58.77 ? 593 HIS A CG 1 ATOM 4255 N ND1 . HIS A 1 567 ? -76.944 -9.478 44.446 1.00 59.05 ? 593 HIS A ND1 1 ATOM 4256 C CD2 . HIS A 1 567 ? -76.600 -8.146 42.751 1.00 65.70 ? 593 HIS A CD2 1 ATOM 4257 C CE1 . HIS A 1 567 ? -77.637 -9.954 43.428 1.00 58.82 ? 593 HIS A CE1 1 ATOM 4258 N NE2 . HIS A 1 567 ? -77.428 -9.175 42.383 1.00 63.54 ? 593 HIS A NE2 1 ATOM 4259 N N . ASN A 1 568 ? -75.779 -4.990 47.614 1.00 42.07 ? 594 ASN A N 1 ATOM 4260 C CA . ASN A 1 568 ? -75.127 -4.192 48.623 1.00 45.89 ? 594 ASN A CA 1 ATOM 4261 C C . ASN A 1 568 ? -75.690 -4.448 50.025 1.00 47.95 ? 594 ASN A C 1 ATOM 4262 O O . ASN A 1 568 ? -75.211 -3.889 51.017 1.00 56.83 ? 594 ASN A O 1 ATOM 4263 C CB . ASN A 1 568 ? -75.254 -2.706 48.258 1.00 42.32 ? 594 ASN A CB 1 ATOM 4264 C CG . ASN A 1 568 ? -74.337 -2.331 47.122 1.00 51.26 ? 594 ASN A CG 1 ATOM 4265 O OD1 . ASN A 1 568 ? -73.199 -2.781 47.081 1.00 49.46 ? 594 ASN A OD1 1 ATOM 4266 N ND2 . ASN A 1 568 ? -74.783 -1.436 46.252 1.00 54.84 ? 594 ASN A ND2 1 ATOM 4267 N N . ASN A 1 569 ? -76.688 -5.309 50.109 1.00 46.91 ? 595 ASN A N 1 ATOM 4268 C CA . ASN A 1 569 ? -77.320 -5.638 51.387 1.00 48.30 ? 595 ASN A CA 1 ATOM 4269 C C . ASN A 1 569 ? -77.662 -4.418 52.203 1.00 48.26 ? 595 ASN A C 1 ATOM 4270 O O . ASN A 1 569 ? -77.445 -4.408 53.417 1.00 50.35 ? 595 ASN A O 1 ATOM 4271 C CB . ASN A 1 569 ? -76.440 -6.536 52.245 1.00 55.54 ? 595 ASN A CB 1 ATOM 4272 C CG . ASN A 1 569 ? -76.164 -7.870 51.609 1.00 65.12 ? 595 ASN A CG 1 ATOM 4273 O OD1 . ASN A 1 569 ? -76.377 -8.898 52.232 1.00 99.56 ? 595 ASN A OD1 1 ATOM 4274 N ND2 . ASN A 1 569 ? -75.798 -7.871 50.344 1.00 77.39 ? 595 ASN A ND2 1 ATOM 4275 N N . ILE A 1 570 ? -78.133 -3.369 51.548 1.00 40.78 ? 596 ILE A N 1 ATOM 4276 C CA . ILE A 1 570 ? -78.495 -2.172 52.274 1.00 48.59 ? 596 ILE A CA 1 ATOM 4277 C C . ILE A 1 570 ? -79.691 -2.475 53.144 1.00 48.76 ? 596 ILE A C 1 ATOM 4278 O O . ILE A 1 570 ? -80.664 -3.030 52.664 1.00 55.89 ? 596 ILE A O 1 ATOM 4279 C CB . ILE A 1 570 ? -78.820 -1.026 51.344 1.00 50.02 ? 596 ILE A CB 1 ATOM 4280 C CG1 . ILE A 1 570 ? -77.588 -0.690 50.517 1.00 54.70 ? 596 ILE A CG1 1 ATOM 4281 C CG2 . ILE A 1 570 ? -79.233 0.191 52.147 1.00 51.38 ? 596 ILE A CG2 1 ATOM 4282 C CD1 . ILE A 1 570 ? -77.860 0.334 49.434 1.00 67.79 ? 596 ILE A CD1 1 ATOM 4283 N N . TYR A 1 571 ? -79.563 -2.196 54.445 1.00 55.02 ? 597 TYR A N 1 ATOM 4284 C CA . TYR A 1 571 ? -80.637 -2.450 55.426 1.00 54.23 ? 597 TYR A CA 1 ATOM 4285 C C . TYR A 1 571 ? -80.834 -1.291 56.364 1.00 50.21 ? 597 TYR A C 1 ATOM 4286 O O . TYR A 1 571 ? -81.605 -1.394 57.281 1.00 67.57 ? 597 TYR A O 1 ATOM 4287 C CB . TYR A 1 571 ? -80.312 -3.660 56.284 1.00 55.41 ? 597 TYR A CB 1 ATOM 4288 C CG . TYR A 1 571 ? -79.221 -3.424 57.314 1.00 63.61 ? 597 TYR A CG 1 ATOM 4289 C CD1 . TYR A 1 571 ? -77.879 -3.593 57.006 1.00 67.30 ? 597 TYR A CD1 1 ATOM 4290 C CD2 . TYR A 1 571 ? -79.547 -3.099 58.625 1.00 71.46 ? 597 TYR A CD2 1 ATOM 4291 C CE1 . TYR A 1 571 ? -76.895 -3.390 57.961 1.00 72.95 ? 597 TYR A CE1 1 ATOM 4292 C CE2 . TYR A 1 571 ? -78.576 -2.911 59.584 1.00 70.09 ? 597 TYR A CE2 1 ATOM 4293 C CZ . TYR A 1 571 ? -77.255 -3.061 59.254 1.00 74.06 ? 597 TYR A CZ 1 ATOM 4294 O OH . TYR A 1 571 ? -76.306 -2.883 60.226 1.00 71.34 ? 597 TYR A OH 1 ATOM 4295 N N . THR A 1 572 ? -80.075 -0.221 56.175 1.00 55.22 ? 598 THR A N 1 ATOM 4296 C CA . THR A 1 572 ? -80.180 0.974 57.003 1.00 53.83 ? 598 THR A CA 1 ATOM 4297 C C . THR A 1 572 ? -79.402 2.120 56.377 1.00 54.10 ? 598 THR A C 1 ATOM 4298 O O . THR A 1 572 ? -78.395 1.894 55.710 1.00 58.19 ? 598 THR A O 1 ATOM 4299 C CB . THR A 1 572 ? -79.608 0.773 58.417 1.00 56.94 ? 598 THR A CB 1 ATOM 4300 O OG1 . THR A 1 572 ? -79.771 1.984 59.153 1.00 54.70 ? 598 THR A OG1 1 ATOM 4301 C CG2 . THR A 1 572 ? -78.132 0.440 58.368 1.00 57.77 ? 598 THR A CG2 1 ATOM 4302 N N . LEU A 1 573 ? -79.855 3.342 56.627 1.00 55.03 ? 599 LEU A N 1 ATOM 4303 C CA . LEU A 1 573 ? -79.192 4.540 56.111 1.00 63.91 ? 599 LEU A CA 1 ATOM 4304 C C . LEU A 1 573 ? -79.006 5.504 57.266 1.00 60.81 ? 599 LEU A C 1 ATOM 4305 O O . LEU A 1 573 ? -79.763 5.486 58.219 1.00 66.18 ? 599 LEU A O 1 ATOM 4306 C CB . LEU A 1 573 ? -80.015 5.221 55.019 1.00 69.83 ? 599 LEU A CB 1 ATOM 4307 C CG . LEU A 1 573 ? -80.313 4.408 53.754 1.00 77.68 ? 599 LEU A CG 1 ATOM 4308 C CD1 . LEU A 1 573 ? -81.111 5.259 52.774 1.00 76.41 ? 599 LEU A CD1 1 ATOM 4309 C CD2 . LEU A 1 573 ? -79.036 3.932 53.099 1.00 72.88 ? 599 LEU A CD2 1 ATOM 4310 N N . THR A 1 574 ? -78.038 6.392 57.146 1.00 56.85 ? 600 THR A N 1 ATOM 4311 C CA . THR A 1 574 ? -77.774 7.335 58.197 1.00 58.82 ? 600 THR A CA 1 ATOM 4312 C C . THR A 1 574 ? -78.243 8.751 57.904 1.00 63.96 ? 600 THR A C 1 ATOM 4313 O O . THR A 1 574 ? -77.892 9.347 56.862 1.00 58.91 ? 600 THR A O 1 ATOM 4314 C CB . THR A 1 574 ? -76.267 7.409 58.473 1.00 64.09 ? 600 THR A CB 1 ATOM 4315 O OG1 . THR A 1 574 ? -75.780 6.102 58.761 1.00 61.73 ? 600 THR A OG1 1 ATOM 4316 C CG2 . THR A 1 574 ? -75.982 8.344 59.646 1.00 63.45 ? 600 THR A CG2 1 ATOM 4317 N N . ASP A 1 575 ? -78.993 9.300 58.856 1.00 63.43 ? 601 ASP A N 1 ATOM 4318 C CA . ASP A 1 575 ? -79.496 10.678 58.776 1.00 79.66 ? 601 ASP A CA 1 ATOM 4319 C C . ASP A 1 575 ? -80.564 10.939 57.720 1.00 75.86 ? 601 ASP A C 1 ATOM 4320 O O . ASP A 1 575 ? -81.668 11.368 58.047 1.00 92.17 ? 601 ASP A O 1 ATOM 4321 C CB . ASP A 1 575 ? -78.325 11.657 58.554 1.00 72.83 ? 601 ASP A CB 1 ATOM 4322 C CG . ASP A 1 575 ? -77.310 11.630 59.685 1.00 83.71 ? 601 ASP A CG 1 ATOM 4323 O OD1 . ASP A 1 575 ? -77.689 11.290 60.843 1.00 86.79 ? 601 ASP A OD1 1 ATOM 4324 O OD2 . ASP A 1 575 ? -76.142 12.005 59.418 1.00 70.95 ? 601 ASP A OD2 1 ATOM 4325 N N . LYS A 1 576 ? -80.232 10.675 56.463 1.00 79.86 ? 602 LYS A N 1 ATOM 4326 C CA . LYS A 1 576 ? -81.147 10.920 55.366 1.00 73.83 ? 602 LYS A CA 1 ATOM 4327 C C . LYS A 1 576 ? -81.646 9.546 54.885 1.00 63.38 ? 602 LYS A C 1 ATOM 4328 O O . LYS A 1 576 ? -80.894 8.734 54.369 1.00 63.25 ? 602 LYS A O 1 ATOM 4329 C CB . LYS A 1 576 ? -80.379 11.744 54.353 1.00 77.01 ? 602 LYS A CB 1 ATOM 4330 C CG . LYS A 1 576 ? -81.223 12.705 53.559 1.00 94.79 ? 602 LYS A CG 1 ATOM 4331 C CD . LYS A 1 576 ? -81.785 12.227 52.244 1.00 99.29 ? 602 LYS A CD 1 ATOM 4332 C CE . LYS A 1 576 ? -82.674 13.358 51.738 1.00 101.57 ? 602 LYS A CE 1 ATOM 4333 N NZ . LYS A 1 576 ? -82.714 13.455 50.253 1.00 103.89 ? 602 LYS A NZ 1 ATOM 4334 N N . TYR A 1 577 ? -82.925 9.282 55.128 1.00 75.26 ? 603 TYR A N 1 ATOM 4335 C CA . TYR A 1 577 ? -83.539 7.976 54.820 1.00 78.85 ? 603 TYR A CA 1 ATOM 4336 C C . TYR A 1 577 ? -84.242 7.783 53.492 1.00 74.59 ? 603 TYR A C 1 ATOM 4337 O O . TYR A 1 577 ? -84.641 6.679 53.188 1.00 78.04 ? 603 TYR A O 1 ATOM 4338 C CB . TYR A 1 577 ? -84.528 7.635 55.944 1.00 70.65 ? 603 TYR A CB 1 ATOM 4339 C CG . TYR A 1 577 ? -83.913 7.930 57.264 1.00 84.44 ? 603 TYR A CG 1 ATOM 4340 C CD1 . TYR A 1 577 ? -82.797 7.222 57.699 1.00 97.61 ? 603 TYR A CD1 1 ATOM 4341 C CD2 . TYR A 1 577 ? -84.407 8.944 58.072 1.00 97.80 ? 603 TYR A CD2 1 ATOM 4342 C CE1 . TYR A 1 577 ? -82.166 7.539 58.886 1.00 108.53 ? 603 TYR A CE1 1 ATOM 4343 C CE2 . TYR A 1 577 ? -83.799 9.251 59.280 1.00 106.50 ? 603 TYR A CE2 1 ATOM 4344 C CZ . TYR A 1 577 ? -82.676 8.550 59.679 1.00 111.96 ? 603 TYR A CZ 1 ATOM 4345 O OH . TYR A 1 577 ? -82.054 8.858 60.869 1.00 103.46 ? 603 TYR A OH 1 ATOM 4346 N N . ASN A 1 578 ? -84.359 8.826 52.687 1.00 76.57 ? 604 ASN A N 1 ATOM 4347 C CA . ASN A 1 578 ? -85.047 8.718 51.409 1.00 70.24 ? 604 ASN A CA 1 ATOM 4348 C C . ASN A 1 578 ? -84.166 9.012 50.219 1.00 70.34 ? 604 ASN A C 1 ATOM 4349 O O . ASN A 1 578 ? -83.401 9.976 50.242 1.00 74.74 ? 604 ASN A O 1 ATOM 4350 C CB . ASN A 1 578 ? -86.118 9.781 51.379 1.00 69.74 ? 604 ASN A CB 1 ATOM 4351 C CG . ASN A 1 578 ? -87.056 9.683 52.535 1.00 70.96 ? 604 ASN A CG 1 ATOM 4352 O OD1 . ASN A 1 578 ? -87.750 8.676 52.715 1.00 66.26 ? 604 ASN A OD1 1 ATOM 4353 N ND2 . ASN A 1 578 ? -87.199 10.787 53.244 1.00 73.62 ? 604 ASN A ND2 1 ATOM 4354 N N . LEU A 1 579 ? -84.323 8.231 49.155 1.00 64.14 ? 605 LEU A N 1 ATOM 4355 C CA . LEU A 1 579 ? -83.570 8.473 47.934 1.00 61.19 ? 605 LEU A CA 1 ATOM 4356 C C . LEU A 1 579 ? -84.406 9.506 47.174 1.00 65.91 ? 605 LEU A C 1 ATOM 4357 O O . LEU A 1 579 ? -85.645 9.456 47.181 1.00 58.86 ? 605 LEU A O 1 ATOM 4358 C CB . LEU A 1 579 ? -83.401 7.209 47.114 1.00 61.92 ? 605 LEU A CB 1 ATOM 4359 C CG . LEU A 1 579 ? -82.788 6.036 47.858 1.00 64.27 ? 605 LEU A CG 1 ATOM 4360 C CD1 . LEU A 1 579 ? -82.570 4.874 46.914 1.00 67.06 ? 605 LEU A CD1 1 ATOM 4361 C CD2 . LEU A 1 579 ? -81.488 6.446 48.495 1.00 61.69 ? 605 LEU A CD2 1 ATOM 4362 N N . GLU A 1 580 ? -83.723 10.459 46.554 1.00 63.55 ? 606 GLU A N 1 ATOM 4363 C CA . GLU A 1 580 ? -84.373 11.526 45.845 1.00 64.80 ? 606 GLU A CA 1 ATOM 4364 C C . GLU A 1 580 ? -83.624 11.981 44.623 1.00 67.69 ? 606 GLU A C 1 ATOM 4365 O O . GLU A 1 580 ? -82.420 12.215 44.676 1.00 68.27 ? 606 GLU A O 1 ATOM 4366 C CB . GLU A 1 580 ? -84.492 12.710 46.771 1.00 71.14 ? 606 GLU A CB 1 ATOM 4367 C CG . GLU A 1 580 ? -85.350 12.426 47.984 1.00 91.25 ? 606 GLU A CG 1 ATOM 4368 C CD . GLU A 1 580 ? -85.419 13.601 48.925 1.00 91.44 ? 606 GLU A CD 1 ATOM 4369 O OE1 . GLU A 1 580 ? -84.673 14.580 48.701 1.00 91.79 ? 606 GLU A OE1 1 ATOM 4370 O OE2 . GLU A 1 580 ? -86.166 13.513 49.921 1.00 102.16 ? 606 GLU A OE2 1 ATOM 4371 N N . SER A 1 581 ? -84.362 12.141 43.529 1.00 64.48 ? 607 SER A N 1 ATOM 4372 C CA . SER A 1 581 ? -83.793 12.593 42.274 1.00 60.02 ? 607 SER A CA 1 ATOM 4373 C C . SER A 1 581 ? -84.896 13.067 41.346 1.00 60.00 ? 607 SER A C 1 ATOM 4374 O O . SER A 1 581 ? -85.905 12.382 41.137 1.00 68.53 ? 607 SER A O 1 ATOM 4375 C CB . SER A 1 581 ? -82.999 11.477 41.590 1.00 60.92 ? 607 SER A CB 1 ATOM 4376 O OG . SER A 1 581 ? -82.431 11.933 40.359 1.00 55.03 ? 607 SER A OG 1 ATOM 4377 N N . LYS A 1 582 ? -84.701 14.254 40.801 1.00 61.85 ? 608 LYS A N 1 ATOM 4378 C CA . LYS A 1 582 ? -85.646 14.822 39.871 1.00 71.91 ? 608 LYS A CA 1 ATOM 4379 C C . LYS A 1 582 ? -85.396 14.256 38.474 1.00 70.11 ? 608 LYS A C 1 ATOM 4380 O O . LYS A 1 582 ? -86.251 14.384 37.606 1.00 77.10 ? 608 LYS A O 1 ATOM 4381 C CB . LYS A 1 582 ? -85.531 16.357 39.850 1.00 68.57 ? 608 LYS A CB 1 ATOM 4382 C CG . LYS A 1 582 ? -85.968 17.001 41.152 1.00 80.57 ? 608 LYS A CG 1 ATOM 4383 C CD . LYS A 1 582 ? -85.885 18.519 41.114 1.00 95.74 ? 608 LYS A CD 1 ATOM 4384 C CE . LYS A 1 582 ? -86.406 19.125 42.416 1.00 102.99 ? 608 LYS A CE 1 ATOM 4385 N NZ . LYS A 1 582 ? -86.354 20.614 42.422 1.00 106.37 ? 608 LYS A NZ 1 ATOM 4386 N N . SER A 1 583 ? -84.263 13.567 38.283 1.00 65.32 ? 609 SER A N 1 ATOM 4387 C CA . SER A 1 583 ? -83.907 13.016 36.959 1.00 59.79 ? 609 SER A CA 1 ATOM 4388 C C . SER A 1 583 ? -83.881 11.522 36.856 1.00 59.25 ? 609 SER A C 1 ATOM 4389 O O . SER A 1 583 ? -84.199 10.964 35.809 1.00 63.42 ? 609 SER A O 1 ATOM 4390 C CB . SER A 1 583 ? -82.523 13.525 36.525 1.00 53.48 ? 609 SER A CB 1 ATOM 4391 O OG . SER A 1 583 ? -81.534 13.138 37.454 1.00 62.50 ? 609 SER A OG 1 ATOM 4392 N N . LEU A 1 584 ? -83.477 10.862 37.924 1.00 59.45 ? 610 LEU A N 1 ATOM 4393 C CA . LEU A 1 584 ? -83.379 9.426 37.874 1.00 61.60 ? 610 LEU A CA 1 ATOM 4394 C C . LEU A 1 584 ? -84.618 8.776 37.245 1.00 56.01 ? 610 LEU A C 1 ATOM 4395 O O . LEU A 1 584 ? -85.738 8.964 37.705 1.00 61.68 ? 610 LEU A O 1 ATOM 4396 C CB . LEU A 1 584 ? -83.110 8.828 39.262 1.00 60.78 ? 610 LEU A CB 1 ATOM 4397 C CG . LEU A 1 584 ? -82.715 7.347 39.220 1.00 53.38 ? 610 LEU A CG 1 ATOM 4398 C CD1 . LEU A 1 584 ? -81.391 7.183 38.510 1.00 54.85 ? 610 LEU A CD1 1 ATOM 4399 C CD2 . LEU A 1 584 ? -82.596 6.779 40.607 1.00 58.54 ? 610 LEU A CD2 1 ATOM 4400 N N . VAL A 1 585 ? -84.338 7.900 36.290 1.00 50.18 ? 611 VAL A N 1 ATOM 4401 C CA . VAL A 1 585 ? -85.325 7.136 35.529 1.00 55.27 ? 611 VAL A CA 1 ATOM 4402 C C . VAL A 1 585 ? -85.401 5.663 35.920 1.00 51.10 ? 611 VAL A C 1 ATOM 4403 O O . VAL A 1 585 ? -86.466 5.073 35.908 1.00 54.65 ? 611 VAL A O 1 ATOM 4404 C CB . VAL A 1 585 ? -84.958 7.177 34.012 1.00 58.11 ? 611 VAL A CB 1 ATOM 4405 C CG1 . VAL A 1 585 ? -85.574 6.019 33.266 1.00 67.46 ? 611 VAL A CG1 1 ATOM 4406 C CG2 . VAL A 1 585 ? -85.330 8.513 33.401 1.00 52.42 ? 611 VAL A CG2 1 ATOM 4407 N N . GLU A 1 586 ? -84.260 5.058 36.206 1.00 56.84 ? 612 GLU A N 1 ATOM 4408 C CA . GLU A 1 586 ? -84.200 3.642 36.571 1.00 57.89 ? 612 GLU A CA 1 ATOM 4409 C C . GLU A 1 586 ? -83.366 3.402 37.837 1.00 56.15 ? 612 GLU A C 1 ATOM 4410 O O . GLU A 1 586 ? -82.235 3.902 37.957 1.00 52.93 ? 612 GLU A O 1 ATOM 4411 C CB . GLU A 1 586 ? -83.569 2.864 35.409 1.00 52.67 ? 612 GLU A CB 1 ATOM 4412 C CG . GLU A 1 586 ? -83.393 1.369 35.632 1.00 52.33 ? 612 GLU A CG 1 ATOM 4413 C CD . GLU A 1 586 ? -82.688 0.670 34.454 1.00 64.14 ? 612 GLU A CD 1 ATOM 4414 O OE1 . GLU A 1 586 ? -82.310 1.353 33.457 1.00 65.66 ? 612 GLU A OE1 1 ATOM 4415 O OE2 . GLU A 1 586 ? -82.488 -0.567 34.532 1.00 59.75 ? 612 GLU A OE2 1 ATOM 4416 N N . LEU A 1 587 ? -83.933 2.628 38.762 1.00 52.74 ? 613 LEU A N 1 ATOM 4417 C CA . LEU A 1 587 ? -83.263 2.262 40.005 1.00 49.89 ? 613 LEU A CA 1 ATOM 4418 C C . LEU A 1 587 ? -83.277 0.748 40.169 1.00 54.78 ? 613 LEU A C 1 ATOM 4419 O O . LEU A 1 587 ? -84.337 0.140 40.212 1.00 47.94 ? 613 LEU A O 1 ATOM 4420 C CB . LEU A 1 587 ? -83.953 2.857 41.222 1.00 49.77 ? 613 LEU A CB 1 ATOM 4421 C CG . LEU A 1 587 ? -83.303 2.481 42.589 1.00 53.50 ? 613 LEU A CG 1 ATOM 4422 C CD1 . LEU A 1 587 ? -81.889 3.037 42.717 1.00 45.89 ? 613 LEU A CD1 1 ATOM 4423 C CD2 . LEU A 1 587 ? -84.141 2.980 43.788 1.00 51.53 ? 613 LEU A CD2 1 ATOM 4424 N N . VAL A 1 588 ? -82.105 0.131 40.157 1.00 51.75 ? 614 VAL A N 1 ATOM 4425 C CA . VAL A 1 588 ? -82.011 -1.297 40.372 1.00 48.93 ? 614 VAL A CA 1 ATOM 4426 C C . VAL A 1 588 ? -81.637 -1.447 41.875 1.00 52.54 ? 614 VAL A C 1 ATOM 4427 O O . VAL A 1 588 ? -80.529 -1.089 42.276 1.00 50.11 ? 614 VAL A O 1 ATOM 4428 C CB . VAL A 1 588 ? -80.921 -1.917 39.510 1.00 50.81 ? 614 VAL A CB 1 ATOM 4429 C CG1 . VAL A 1 588 ? -80.812 -3.406 39.792 1.00 52.75 ? 614 VAL A CG1 1 ATOM 4430 C CG2 . VAL A 1 588 ? -81.175 -1.648 38.033 1.00 52.93 ? 614 VAL A CG2 1 ATOM 4431 N N . PHE A 1 589 ? -82.531 -2.021 42.684 1.00 49.69 ? 615 PHE A N 1 ATOM 4432 C CA . PHE A 1 589 ? -82.286 -2.167 44.113 1.00 40.49 ? 615 PHE A CA 1 ATOM 4433 C C . PHE A 1 589 ? -82.385 -3.593 44.560 1.00 43.01 ? 615 PHE A C 1 ATOM 4434 O O . PHE A 1 589 ? -82.773 -3.882 45.682 1.00 44.76 ? 615 PHE A O 1 ATOM 4435 C CB . PHE A 1 589 ? -83.317 -1.355 44.851 1.00 44.76 ? 615 PHE A CB 1 ATOM 4436 C CG . PHE A 1 589 ? -82.952 -1.039 46.274 1.00 48.47 ? 615 PHE A CG 1 ATOM 4437 C CD1 . PHE A 1 589 ? -82.133 0.029 46.546 1.00 47.29 ? 615 PHE A CD1 1 ATOM 4438 C CD2 . PHE A 1 589 ? -83.562 -1.681 47.323 1.00 53.28 ? 615 PHE A CD2 1 ATOM 4439 C CE1 . PHE A 1 589 ? -81.858 0.399 47.832 1.00 50.44 ? 615 PHE A CE1 1 ATOM 4440 C CE2 . PHE A 1 589 ? -83.273 -1.325 48.611 1.00 52.59 ? 615 PHE A CE2 1 ATOM 4441 C CZ . PHE A 1 589 ? -82.431 -0.275 48.865 1.00 48.74 ? 615 PHE A CZ 1 ATOM 4442 N N . SER A 1 590 ? -82.037 -4.510 43.681 1.00 46.68 ? 616 SER A N 1 ATOM 4443 C CA . SER A 1 590 ? -82.127 -5.891 44.044 1.00 46.98 ? 616 SER A CA 1 ATOM 4444 C C . SER A 1 590 ? -80.978 -6.356 44.928 1.00 45.02 ? 616 SER A C 1 ATOM 4445 O O . SER A 1 590 ? -79.919 -5.788 44.912 1.00 51.36 ? 616 SER A O 1 ATOM 4446 C CB . SER A 1 590 ? -82.184 -6.749 42.785 1.00 45.52 ? 616 SER A CB 1 ATOM 4447 O OG . SER A 1 590 ? -81.005 -6.660 42.068 1.00 45.30 ? 616 SER A OG 1 ATOM 4448 N N . GLY A 1 591 ? -81.202 -7.386 45.710 1.00 50.46 ? 617 GLY A N 1 ATOM 4449 C CA . GLY A 1 591 ? -80.149 -7.942 46.506 1.00 45.76 ? 617 GLY A CA 1 ATOM 4450 C C . GLY A 1 591 ? -79.790 -7.122 47.697 1.00 48.30 ? 617 GLY A C 1 ATOM 4451 O O . GLY A 1 591 ? -78.740 -7.276 48.239 1.00 53.56 ? 617 GLY A O 1 ATOM 4452 N N . ASN A 1 592 ? -80.667 -6.224 48.074 1.00 49.70 ? 618 ASN A N 1 ATOM 4453 C CA . ASN A 1 592 ? -80.535 -5.439 49.273 1.00 47.76 ? 618 ASN A CA 1 ATOM 4454 C C . ASN A 1 592 ? -81.454 -5.992 50.338 1.00 52.91 ? 618 ASN A C 1 ATOM 4455 O O . ASN A 1 592 ? -81.827 -7.125 50.248 1.00 51.39 ? 618 ASN A O 1 ATOM 4456 C CB . ASN A 1 592 ? -80.809 -3.987 48.966 1.00 48.71 ? 618 ASN A CB 1 ATOM 4457 C CG . ASN A 1 592 ? -79.694 -3.345 48.197 1.00 56.50 ? 618 ASN A CG 1 ATOM 4458 O OD1 . ASN A 1 592 ? -78.610 -3.215 48.681 1.00 67.24 ? 618 ASN A OD1 1 ATOM 4459 N ND2 . ASN A 1 592 ? -79.963 -2.944 47.002 1.00 64.29 ? 618 ASN A ND2 1 ATOM 4460 N N . ARG A 1 593 ? -81.798 -5.221 51.358 1.00 49.13 ? 619 ARG A N 1 ATOM 4461 C CA . ARG A 1 593 ? -82.667 -5.732 52.404 1.00 54.72 ? 619 ARG A CA 1 ATOM 4462 C C . ARG A 1 593 ? -83.861 -4.855 52.745 1.00 57.28 ? 619 ARG A C 1 ATOM 4463 O O . ARG A 1 593 ? -83.976 -4.344 53.822 1.00 62.25 ? 619 ARG A O 1 ATOM 4464 C CB . ARG A 1 593 ? -81.864 -6.015 53.667 1.00 55.03 ? 619 ARG A CB 1 ATOM 4465 C CG . ARG A 1 593 ? -80.644 -6.862 53.470 1.00 48.25 ? 619 ARG A CG 1 ATOM 4466 C CD . ARG A 1 593 ? -80.958 -8.328 53.479 1.00 49.31 ? 619 ARG A CD 1 ATOM 4467 N NE . ARG A 1 593 ? -82.030 -8.659 54.386 1.00 61.13 ? 619 ARG A NE 1 ATOM 4468 C CZ . ARG A 1 593 ? -81.893 -9.442 55.441 1.00 69.36 ? 619 ARG A CZ 1 ATOM 4469 N NH1 . ARG A 1 593 ? -80.726 -9.962 55.728 1.00 63.36 ? 619 ARG A NH1 1 ATOM 4470 N NH2 . ARG A 1 593 ? -82.921 -9.697 56.211 1.00 62.93 ? 619 ARG A NH2 1 ATOM 4471 N N . LEU A 1 594 ? -84.796 -4.753 51.829 1.00 63.98 ? 620 LEU A N 1 ATOM 4472 C CA . LEU A 1 594 ? -86.008 -4.003 52.049 1.00 60.81 ? 620 LEU A CA 1 ATOM 4473 C C . LEU A 1 594 ? -86.829 -4.613 53.134 1.00 53.60 ? 620 LEU A C 1 ATOM 4474 O O . LEU A 1 594 ? -87.638 -3.950 53.734 1.00 59.82 ? 620 LEU A O 1 ATOM 4475 C CB . LEU A 1 594 ? -86.840 -3.958 50.793 1.00 68.16 ? 620 LEU A CB 1 ATOM 4476 C CG . LEU A 1 594 ? -86.589 -2.798 49.874 1.00 68.80 ? 620 LEU A CG 1 ATOM 4477 C CD1 . LEU A 1 594 ? -87.503 -2.941 48.692 1.00 81.22 ? 620 LEU A CD1 1 ATOM 4478 C CD2 . LEU A 1 594 ? -86.837 -1.497 50.588 1.00 67.80 ? 620 LEU A CD2 1 ATOM 4479 N N . ASP A 1 595 ? -86.670 -5.904 53.340 1.00 49.27 ? 621 ASP A N 1 ATOM 4480 C CA . ASP A 1 595 ? -87.476 -6.580 54.315 1.00 58.60 ? 621 ASP A CA 1 ATOM 4481 C C . ASP A 1 595 ? -87.187 -5.948 55.633 1.00 60.55 ? 621 ASP A C 1 ATOM 4482 O O . ASP A 1 595 ? -88.073 -5.739 56.415 1.00 72.06 ? 621 ASP A O 1 ATOM 4483 C CB . ASP A 1 595 ? -87.160 -8.052 54.363 1.00 61.45 ? 621 ASP A CB 1 ATOM 4484 C CG . ASP A 1 595 ? -85.750 -8.317 54.694 1.00 66.80 ? 621 ASP A CG 1 ATOM 4485 O OD1 . ASP A 1 595 ? -84.925 -7.461 54.406 1.00 69.86 ? 621 ASP A OD1 1 ATOM 4486 O OD2 . ASP A 1 595 ? -85.456 -9.380 55.239 1.00 64.32 ? 621 ASP A OD2 1 ATOM 4487 N N . ILE A 1 596 ? -85.933 -5.624 55.875 1.00 65.27 ? 622 ILE A N 1 ATOM 4488 C CA . ILE A 1 596 ? -85.552 -4.935 57.097 1.00 51.30 ? 622 ILE A CA 1 ATOM 4489 C C . ILE A 1 596 ? -85.886 -3.455 57.077 1.00 48.87 ? 622 ILE A C 1 ATOM 4490 O O . ILE A 1 596 ? -86.349 -2.924 58.056 1.00 56.46 ? 622 ILE A O 1 ATOM 4491 C CB . ILE A 1 596 ? -84.082 -5.178 57.406 1.00 56.74 ? 622 ILE A CB 1 ATOM 4492 C CG1 . ILE A 1 596 ? -83.887 -6.662 57.761 1.00 52.05 ? 622 ILE A CG1 1 ATOM 4493 C CG2 . ILE A 1 596 ? -83.619 -4.296 58.547 1.00 53.18 ? 622 ILE A CG2 1 ATOM 4494 C CD1 . ILE A 1 596 ? -82.442 -7.106 57.830 1.00 55.12 ? 622 ILE A CD1 1 ATOM 4495 N N . LEU A 1 597 ? -85.644 -2.773 55.978 1.00 53.07 ? 623 LEU A N 1 ATOM 4496 C CA . LEU A 1 597 ? -85.949 -1.334 55.914 1.00 54.21 ? 623 LEU A CA 1 ATOM 4497 C C . LEU A 1 597 ? -87.422 -1.053 56.136 1.00 60.08 ? 623 LEU A C 1 ATOM 4498 O O . LEU A 1 597 ? -87.771 -0.123 56.833 1.00 73.48 ? 623 LEU A O 1 ATOM 4499 C CB . LEU A 1 597 ? -85.520 -0.779 54.564 1.00 53.41 ? 623 LEU A CB 1 ATOM 4500 C CG . LEU A 1 597 ? -84.011 -0.733 54.335 1.00 59.14 ? 623 LEU A CG 1 ATOM 4501 C CD1 . LEU A 1 597 ? -83.665 -0.675 52.855 1.00 58.41 ? 623 LEU A CD1 1 ATOM 4502 C CD2 . LEU A 1 597 ? -83.373 0.427 55.123 1.00 59.32 ? 623 LEU A CD2 1 ATOM 4503 N N . TRP A 1 598 ? -88.284 -1.822 55.476 1.00 72.05 ? 624 TRP A N 1 ATOM 4504 C CA . TRP A 1 598 ? -89.719 -1.640 55.611 1.00 71.78 ? 624 TRP A CA 1 ATOM 4505 C C . TRP A 1 598 ? -90.369 -2.523 56.653 1.00 80.58 ? 624 TRP A C 1 ATOM 4506 O O . TRP A 1 598 ? -91.086 -2.041 57.492 1.00 70.27 ? 624 TRP A O 1 ATOM 4507 C CB . TRP A 1 598 ? -90.483 -1.978 54.319 1.00 68.35 ? 624 TRP A CB 1 ATOM 4508 C CG . TRP A 1 598 ? -90.293 -1.122 53.171 1.00 68.23 ? 624 TRP A CG 1 ATOM 4509 C CD1 . TRP A 1 598 ? -90.243 0.248 53.194 1.00 61.33 ? 624 TRP A CD1 1 ATOM 4510 C CD2 . TRP A 1 598 ? -90.621 -1.470 51.798 1.00 59.14 ? 624 TRP A CD2 1 ATOM 4511 N NE1 . TRP A 1 598 ? -90.241 0.737 51.908 1.00 66.04 ? 624 TRP A NE1 1 ATOM 4512 C CE2 . TRP A 1 598 ? -90.528 -0.292 51.039 1.00 64.45 ? 624 TRP A CE2 1 ATOM 4513 C CE3 . TRP A 1 598 ? -90.911 -2.668 51.143 1.00 64.05 ? 624 TRP A CE3 1 ATOM 4514 C CZ2 . TRP A 1 598 ? -90.715 -0.279 49.657 1.00 67.70 ? 624 TRP A CZ2 1 ATOM 4515 C CZ3 . TRP A 1 598 ? -91.081 -2.656 49.769 1.00 67.85 ? 624 TRP A CZ3 1 ATOM 4516 C CH2 . TRP A 1 598 ? -90.981 -1.474 49.043 1.00 70.29 ? 624 TRP A CH2 1 ATOM 4517 N N . ASN A 1 599 ? -90.188 -3.840 56.510 1.00 106.34 ? 625 ASN A N 1 ATOM 4518 C CA . ASN A 1 599 ? -90.838 -4.840 57.395 1.00 112.30 ? 625 ASN A CA 1 ATOM 4519 C C . ASN A 1 599 ? -90.687 -4.607 58.886 1.00 111.46 ? 625 ASN A C 1 ATOM 4520 O O . ASN A 1 599 ? -91.342 -5.274 59.693 1.00 132.11 ? 625 ASN A O 1 ATOM 4521 C CB . ASN A 1 599 ? -90.506 -6.309 56.998 1.00 118.54 ? 625 ASN A CB 1 ATOM 4522 C CG . ASN A 1 599 ? -91.042 -6.698 55.591 1.00 115.18 ? 625 ASN A CG 1 ATOM 4523 O OD1 . ASN A 1 599 ? -91.026 -7.893 55.188 1.00 86.66 ? 625 ASN A OD1 1 ATOM 4524 N ND2 . ASN A 1 599 ? -91.524 -5.702 54.844 1.00 101.30 ? 625 ASN A ND2 1 ATOM 4525 N N . ASP A 1 600 ? -89.799 -3.695 59.256 1.00 90.42 ? 626 ASP A N 1 ATOM 4526 C CA . ASP A 1 600 ? -89.627 -3.343 60.656 1.00 105.37 ? 626 ASP A CA 1 ATOM 4527 C C . ASP A 1 600 ? -89.393 -1.850 60.622 1.00 96.79 ? 626 ASP A C 1 ATOM 4528 O O . ASP A 1 600 ? -89.282 -1.264 59.542 1.00 80.74 ? 626 ASP A O 1 ATOM 4529 C CB . ASP A 1 600 ? -88.344 -3.945 61.277 1.00 116.50 ? 626 ASP A CB 1 ATOM 4530 C CG . ASP A 1 600 ? -88.198 -5.439 61.045 1.00 132.00 ? 626 ASP A CG 1 ATOM 4531 O OD1 . ASP A 1 600 ? -87.034 -5.918 61.076 1.00 113.99 ? 626 ASP A OD1 1 ATOM 4532 O OD2 . ASP A 1 600 ? -89.213 -6.117 60.764 1.00 132.62 ? 626 ASP A OD2 1 ATOM 4533 N N . ASP A 1 601 ? -89.502 -1.240 61.787 1.00 105.84 ? 627 ASP A N 1 ATOM 4534 C CA . ASP A 1 601 ? -89.130 0.140 61.927 1.00 108.90 ? 627 ASP A CA 1 ATOM 4535 C C . ASP A 1 601 ? -90.099 1.108 62.609 1.00 110.19 ? 627 ASP A C 1 ATOM 4536 O O . ASP A 1 601 ? -91.007 0.726 63.329 1.00 92.84 ? 627 ASP A O 1 ATOM 4537 C CB . ASP A 1 601 ? -88.689 0.680 60.582 1.00 96.79 ? 627 ASP A CB 1 ATOM 4538 C CG . ASP A 1 601 ? -87.729 1.795 60.732 1.00 100.59 ? 627 ASP A CG 1 ATOM 4539 O OD1 . ASP A 1 601 ? -88.166 2.946 60.616 1.00 104.76 ? 627 ASP A OD1 1 ATOM 4540 O OD2 . ASP A 1 601 ? -86.556 1.525 61.021 1.00 96.11 ? 627 ASP A OD2 1 ATOM 4541 N N . ASP A 1 602 ? -89.808 2.382 62.396 1.00 122.88 ? 628 ASP A N 1 ATOM 4542 C CA . ASP A 1 602 ? -90.626 3.512 62.767 1.00 106.14 ? 628 ASP A CA 1 ATOM 4543 C C . ASP A 1 602 ? -91.165 4.123 61.498 1.00 108.61 ? 628 ASP A C 1 ATOM 4544 O O . ASP A 1 602 ? -91.467 5.304 61.457 1.00 92.01 ? 628 ASP A O 1 ATOM 4545 C CB . ASP A 1 602 ? -89.788 4.553 63.469 1.00 105.97 ? 628 ASP A CB 1 ATOM 4546 C CG . ASP A 1 602 ? -90.166 4.717 64.894 1.00 108.89 ? 628 ASP A CG 1 ATOM 4547 O OD1 . ASP A 1 602 ? -89.910 5.795 65.451 1.00 107.06 ? 628 ASP A OD1 1 ATOM 4548 O OD2 . ASP A 1 602 ? -90.721 3.766 65.457 1.00 112.17 ? 628 ASP A OD2 1 ATOM 4549 N N . ASN A 1 603 ? -91.240 3.330 60.444 1.00 91.22 ? 629 ASN A N 1 ATOM 4550 C CA . ASN A 1 603 ? -91.620 3.859 59.168 1.00 92.09 ? 629 ASN A CA 1 ATOM 4551 C C . ASN A 1 603 ? -90.583 4.830 58.692 1.00 88.29 ? 629 ASN A C 1 ATOM 4552 O O . ASN A 1 603 ? -90.889 5.819 58.060 1.00 83.57 ? 629 ASN A O 1 ATOM 4553 C CB . ASN A 1 603 ? -92.941 4.581 59.308 1.00 97.09 ? 629 ASN A CB 1 ATOM 4554 C CG . ASN A 1 603 ? -94.040 3.681 59.792 1.00 93.18 ? 629 ASN A CG 1 ATOM 4555 O OD1 . ASN A 1 603 ? -94.929 4.112 60.506 1.00 109.58 ? 629 ASN A OD1 1 ATOM 4556 N ND2 . ASN A 1 603 ? -93.987 2.425 59.405 1.00 88.72 ? 629 ASN A ND2 1 ATOM 4557 N N . ARG A 1 604 ? -89.338 4.549 59.020 1.00 89.91 ? 630 ARG A N 1 ATOM 4558 C CA . ARG A 1 604 ? -88.260 5.410 58.603 1.00 84.36 ? 630 ARG A CA 1 ATOM 4559 C C . ARG A 1 604 ? -88.170 5.437 57.099 1.00 80.64 ? 630 ARG A C 1 ATOM 4560 O O . ARG A 1 604 ? -88.013 6.484 56.506 1.00 66.01 ? 630 ARG A O 1 ATOM 4561 C CB . ARG A 1 604 ? -86.957 4.885 59.173 1.00 95.83 ? 630 ARG A CB 1 ATOM 4562 C CG . ARG A 1 604 ? -86.088 5.913 59.855 1.00 103.68 ? 630 ARG A CG 1 ATOM 4563 C CD . ARG A 1 604 ? -85.232 5.259 60.919 1.00 109.12 ? 630 ARG A CD 1 ATOM 4564 N NE . ARG A 1 604 ? -85.213 6.070 62.122 1.00 115.30 ? 630 ARG A NE 1 ATOM 4565 C CZ . ARG A 1 604 ? -84.158 6.741 62.541 1.00 105.22 ? 630 ARG A CZ 1 ATOM 4566 N NH1 . ARG A 1 604 ? -83.029 6.679 61.857 1.00 97.90 ? 630 ARG A NH1 1 ATOM 4567 N NH2 . ARG A 1 604 ? -84.236 7.470 63.640 1.00 107.82 ? 630 ARG A NH2 1 ATOM 4568 N N . TYR A 1 605 ? -88.297 4.273 56.486 1.00 75.83 ? 631 TYR A N 1 ATOM 4569 C CA . TYR A 1 605 ? -88.127 4.132 55.042 1.00 80.09 ? 631 TYR A CA 1 ATOM 4570 C C . TYR A 1 605 ? -89.463 3.818 54.356 1.00 77.83 ? 631 TYR A C 1 ATOM 4571 O O . TYR A 1 605 ? -89.517 3.112 53.343 1.00 73.38 ? 631 TYR A O 1 ATOM 4572 C CB . TYR A 1 605 ? -87.103 3.002 54.777 1.00 79.71 ? 631 TYR A CB 1 ATOM 4573 C CG . TYR A 1 605 ? -85.839 3.128 55.615 1.00 68.43 ? 631 TYR A CG 1 ATOM 4574 C CD1 . TYR A 1 605 ? -84.836 4.000 55.261 1.00 61.89 ? 631 TYR A CD1 1 ATOM 4575 C CD2 . TYR A 1 605 ? -85.669 2.369 56.774 1.00 70.60 ? 631 TYR A CD2 1 ATOM 4576 C CE1 . TYR A 1 605 ? -83.712 4.146 56.042 1.00 67.89 ? 631 TYR A CE1 1 ATOM 4577 C CE2 . TYR A 1 605 ? -84.544 2.498 57.562 1.00 58.80 ? 631 TYR A CE2 1 ATOM 4578 C CZ . TYR A 1 605 ? -83.566 3.392 57.195 1.00 67.77 ? 631 TYR A CZ 1 ATOM 4579 O OH . TYR A 1 605 ? -82.422 3.531 57.962 1.00 63.47 ? 631 TYR A OH 1 ATOM 4580 N N . ILE A 1 606 ? -90.533 4.419 54.850 1.00 71.64 ? 632 ILE A N 1 ATOM 4581 C CA . ILE A 1 606 ? -91.842 4.149 54.295 1.00 67.46 ? 632 ILE A CA 1 ATOM 4582 C C . ILE A 1 606 ? -92.007 4.868 52.960 1.00 66.13 ? 632 ILE A C 1 ATOM 4583 O O . ILE A 1 606 ? -92.707 4.399 52.081 1.00 80.10 ? 632 ILE A O 1 ATOM 4584 C CB . ILE A 1 606 ? -92.951 4.583 55.270 1.00 78.08 ? 632 ILE A CB 1 ATOM 4585 C CG1 . ILE A 1 606 ? -94.172 3.685 55.111 1.00 82.11 ? 632 ILE A CG1 1 ATOM 4586 C CG2 . ILE A 1 606 ? -93.209 6.097 55.215 1.00 73.46 ? 632 ILE A CG2 1 ATOM 4587 C CD1 . ILE A 1 606 ? -93.874 2.252 55.499 1.00 83.23 ? 632 ILE A CD1 1 ATOM 4588 N N . SER A 1 607 ? -91.278 5.964 52.797 1.00 64.73 ? 633 SER A N 1 ATOM 4589 C CA . SER A 1 607 ? -91.310 6.768 51.584 1.00 69.48 ? 633 SER A CA 1 ATOM 4590 C C . SER A 1 607 ? -89.913 6.808 50.965 1.00 70.09 ? 633 SER A C 1 ATOM 4591 O O . SER A 1 607 ? -89.498 7.819 50.364 1.00 66.43 ? 633 SER A O 1 ATOM 4592 C CB . SER A 1 607 ? -91.714 8.188 51.963 1.00 70.55 ? 633 SER A CB 1 ATOM 4593 O OG . SER A 1 607 ? -92.934 8.160 52.670 1.00 84.72 ? 633 SER A OG 1 ATOM 4594 N N . ILE A 1 608 ? -89.209 5.689 51.052 1.00 62.06 ? 634 ILE A N 1 ATOM 4595 C CA . ILE A 1 608 ? -87.843 5.642 50.556 1.00 65.58 ? 634 ILE A CA 1 ATOM 4596 C C . ILE A 1 608 ? -87.633 5.987 49.079 1.00 63.75 ? 634 ILE A C 1 ATOM 4597 O O . ILE A 1 608 ? -86.664 6.679 48.739 1.00 63.08 ? 634 ILE A O 1 ATOM 4598 C CB . ILE A 1 608 ? -87.172 4.304 50.884 1.00 67.24 ? 634 ILE A CB 1 ATOM 4599 C CG1 . ILE A 1 608 ? -85.657 4.408 50.624 1.00 69.81 ? 634 ILE A CG1 1 ATOM 4600 C CG2 . ILE A 1 608 ? -87.836 3.171 50.109 1.00 66.89 ? 634 ILE A CG2 1 ATOM 4601 C CD1 . ILE A 1 608 ? -84.863 3.197 51.061 1.00 61.72 ? 634 ILE A CD1 1 ATOM 4602 N N . PHE A 1 609 ? -88.521 5.524 48.199 1.00 70.44 ? 635 PHE A N 1 ATOM 4603 C CA . PHE A 1 609 ? -88.357 5.815 46.770 1.00 70.83 ? 635 PHE A CA 1 ATOM 4604 C C . PHE A 1 609 ? -89.256 6.938 46.248 1.00 70.03 ? 635 PHE A C 1 ATOM 4605 O O . PHE A 1 609 ? -89.043 7.439 45.151 1.00 57.58 ? 635 PHE A O 1 ATOM 4606 C CB . PHE A 1 609 ? -88.588 4.560 45.931 1.00 66.39 ? 635 PHE A CB 1 ATOM 4607 C CG . PHE A 1 609 ? -87.803 3.380 46.393 1.00 63.94 ? 635 PHE A CG 1 ATOM 4608 C CD1 . PHE A 1 609 ? -86.426 3.358 46.267 1.00 66.53 ? 635 PHE A CD1 1 ATOM 4609 C CD2 . PHE A 1 609 ? -88.446 2.269 46.904 1.00 64.63 ? 635 PHE A CD2 1 ATOM 4610 C CE1 . PHE A 1 609 ? -85.694 2.284 46.715 1.00 62.59 ? 635 PHE A CE1 1 ATOM 4611 C CE2 . PHE A 1 609 ? -87.723 1.178 47.337 1.00 68.10 ? 635 PHE A CE2 1 ATOM 4612 C CZ . PHE A 1 609 ? -86.340 1.183 47.224 1.00 67.08 ? 635 PHE A CZ 1 ATOM 4613 N N . LYS A 1 610 ? -90.191 7.392 47.068 1.00 72.49 ? 636 LYS A N 1 ATOM 4614 C CA . LYS A 1 610 ? -91.127 8.425 46.647 1.00 82.69 ? 636 LYS A CA 1 ATOM 4615 C C . LYS A 1 610 ? -90.489 9.642 45.968 1.00 73.93 ? 636 LYS A C 1 ATOM 4616 O O . LYS A 1 610 ? -90.998 10.123 44.953 1.00 73.67 ? 636 LYS A O 1 ATOM 4617 C CB . LYS A 1 610 ? -91.986 8.867 47.834 1.00 90.09 ? 636 LYS A CB 1 ATOM 4618 C CG . LYS A 1 610 ? -93.092 9.846 47.478 1.00 94.13 ? 636 LYS A CG 1 ATOM 4619 C CD . LYS A 1 610 ? -93.888 10.222 48.719 1.00 115.47 ? 636 LYS A CD 1 ATOM 4620 C CE . LYS A 1 610 ? -94.998 11.216 48.414 1.00 115.58 ? 636 LYS A CE 1 ATOM 4621 N NZ . LYS A 1 610 ? -96.009 10.652 47.484 1.00 114.51 ? 636 LYS A NZ 1 ATOM 4622 N N . GLY A 1 611 ? -89.355 10.100 46.491 1.00 69.59 ? 637 GLY A N 1 ATOM 4623 C CA . GLY A 1 611 ? -88.652 11.286 45.947 1.00 62.09 ? 637 GLY A CA 1 ATOM 4624 C C . GLY A 1 611 ? -87.949 11.105 44.614 1.00 64.18 ? 637 GLY A C 1 ATOM 4625 O O . GLY A 1 611 ? -87.139 11.944 44.208 1.00 65.92 ? 637 GLY A O 1 ATOM 4626 N N . LEU A 1 612 ? -88.176 9.954 43.995 1.00 62.45 ? 638 LEU A N 1 ATOM 4627 C CA . LEU A 1 612 ? -87.624 9.627 42.701 1.00 68.97 ? 638 LEU A CA 1 ATOM 4628 C C . LEU A 1 612 ? -88.771 9.957 41.739 1.00 72.01 ? 638 LEU A C 1 ATOM 4629 O O . LEU A 1 612 ? -89.419 9.082 41.145 1.00 70.87 ? 638 LEU A O 1 ATOM 4630 C CB . LEU A 1 612 ? -87.221 8.151 42.674 1.00 64.95 ? 638 LEU A CB 1 ATOM 4631 C CG . LEU A 1 612 ? -86.117 7.827 43.681 1.00 64.63 ? 638 LEU A CG 1 ATOM 4632 C CD1 . LEU A 1 612 ? -85.837 6.343 43.712 1.00 67.03 ? 638 LEU A CD1 1 ATOM 4633 C CD2 . LEU A 1 612 ? -84.847 8.602 43.372 1.00 65.63 ? 638 LEU A CD2 1 ATOM 4634 N N . LYS A 1 613 ? -89.023 11.259 41.657 1.00 73.81 ? 639 LYS A N 1 ATOM 4635 C CA . LYS A 1 613 ? -90.107 11.853 40.872 1.00 78.94 ? 639 LYS A CA 1 ATOM 4636 C C . LYS A 1 613 ? -90.216 11.515 39.400 1.00 71.38 ? 639 LYS A C 1 ATOM 4637 O O . LYS A 1 613 ? -91.308 11.535 38.855 1.00 89.97 ? 639 LYS A O 1 ATOM 4638 C CB . LYS A 1 613 ? -90.068 13.386 41.037 1.00 85.27 ? 639 LYS A CB 1 ATOM 4639 C CG . LYS A 1 613 ? -90.355 13.865 42.457 1.00 95.61 ? 639 LYS A CG 1 ATOM 4640 C CD . LYS A 1 613 ? -91.773 13.480 42.902 1.00 114.29 ? 639 LYS A CD 1 ATOM 4641 C CE . LYS A 1 613 ? -92.067 13.856 44.354 1.00 127.63 ? 639 LYS A CE 1 ATOM 4642 N NZ . LYS A 1 613 ? -91.979 15.318 44.640 1.00 136.27 ? 639 LYS A NZ 1 ATOM 4643 N N . ASN A 1 614 ? -89.125 11.114 38.777 1.00 72.54 ? 640 ASN A N 1 ATOM 4644 C CA . ASN A 1 614 ? -89.148 10.829 37.346 1.00 64.40 ? 640 ASN A CA 1 ATOM 4645 C C . ASN A 1 614 ? -88.852 9.376 37.069 1.00 65.04 ? 640 ASN A C 1 ATOM 4646 O O . ASN A 1 614 ? -88.626 8.996 35.934 1.00 60.97 ? 640 ASN A O 1 ATOM 4647 C CB . ASN A 1 614 ? -88.078 11.710 36.696 1.00 59.75 ? 640 ASN A CB 1 ATOM 4648 C CG . ASN A 1 614 ? -88.183 11.789 35.190 1.00 64.87 ? 640 ASN A CG 1 ATOM 4649 O OD1 . ASN A 1 614 ? -89.096 11.258 34.571 1.00 87.10 ? 640 ASN A OD1 1 ATOM 4650 N ND2 . ASN A 1 614 ? -87.235 12.489 34.600 1.00 65.66 ? 640 ASN A ND2 1 ATOM 4651 N N . LEU A 1 615 ? -89.008 8.534 38.077 1.00 64.51 ? 641 LEU A N 1 ATOM 4652 C CA . LEU A 1 615 ? -88.670 7.138 37.911 1.00 62.23 ? 641 LEU A CA 1 ATOM 4653 C C . LEU A 1 615 ? -89.693 6.362 37.120 1.00 58.08 ? 641 LEU A C 1 ATOM 4654 O O . LEU A 1 615 ? -90.870 6.399 37.445 1.00 67.41 ? 641 LEU A O 1 ATOM 4655 C CB . LEU A 1 615 ? -88.539 6.492 39.305 1.00 66.41 ? 641 LEU A CB 1 ATOM 4656 C CG . LEU A 1 615 ? -87.863 5.122 39.397 1.00 62.11 ? 641 LEU A CG 1 ATOM 4657 C CD1 . LEU A 1 615 ? -86.383 5.308 39.094 1.00 63.97 ? 641 LEU A CD1 1 ATOM 4658 C CD2 . LEU A 1 615 ? -88.012 4.528 40.780 1.00 64.37 ? 641 LEU A CD2 1 ATOM 4659 N N . THR A 1 616 ? -89.229 5.552 36.176 1.00 61.02 ? 642 THR A N 1 ATOM 4660 C CA . THR A 1 616 ? -90.130 4.703 35.379 1.00 61.07 ? 642 THR A CA 1 ATOM 4661 C C . THR A 1 616 ? -89.866 3.205 35.546 1.00 60.37 ? 642 THR A C 1 ATOM 4662 O O . THR A 1 616 ? -90.733 2.396 35.219 1.00 65.44 ? 642 THR A O 1 ATOM 4663 C CB . THR A 1 616 ? -90.111 5.050 33.891 1.00 59.49 ? 642 THR A CB 1 ATOM 4664 O OG1 . THR A 1 616 ? -88.800 4.874 33.356 1.00 60.93 ? 642 THR A OG1 1 ATOM 4665 C CG2 . THR A 1 616 ? -90.528 6.462 33.698 1.00 66.31 ? 642 THR A CG2 1 ATOM 4666 N N . ARG A 1 617 ? -88.645 2.826 35.921 1.00 60.28 ? 643 ARG A N 1 ATOM 4667 C CA . ARG A 1 617 ? -88.307 1.395 36.158 1.00 63.50 ? 643 ARG A CA 1 ATOM 4668 C C . ARG A 1 617 ? -87.761 1.210 37.576 1.00 64.11 ? 643 ARG A C 1 ATOM 4669 O O . ARG A 1 617 ? -86.924 1.989 38.027 1.00 62.00 ? 643 ARG A O 1 ATOM 4670 C CB . ARG A 1 617 ? -87.289 0.815 35.160 1.00 61.36 ? 643 ARG A CB 1 ATOM 4671 C CG . ARG A 1 617 ? -87.775 0.542 33.736 1.00 89.76 ? 643 ARG A CG 1 ATOM 4672 C CD . ARG A 1 617 ? -88.051 1.757 32.849 1.00 97.47 ? 643 ARG A CD 1 ATOM 4673 N NE . ARG A 1 617 ? -86.826 2.496 32.574 1.00 111.98 ? 643 ARG A NE 1 ATOM 4674 C CZ . ARG A 1 617 ? -85.950 2.169 31.630 1.00 111.60 ? 643 ARG A CZ 1 ATOM 4675 N NH1 . ARG A 1 617 ? -84.842 2.889 31.469 1.00 105.89 ? 643 ARG A NH1 1 ATOM 4676 N NH2 . ARG A 1 617 ? -86.160 1.098 30.873 1.00 110.89 ? 643 ARG A NH2 1 ATOM 4677 N N . LEU A 1 618 ? -88.215 0.156 38.254 1.00 58.32 ? 644 LEU A N 1 ATOM 4678 C CA . LEU A 1 618 ? -87.771 -0.144 39.616 1.00 56.19 ? 644 LEU A CA 1 ATOM 4679 C C . LEU A 1 618 ? -87.646 -1.650 39.851 1.00 54.38 ? 644 LEU A C 1 ATOM 4680 O O . LEU A 1 618 ? -88.600 -2.396 39.688 1.00 58.06 ? 644 LEU A O 1 ATOM 4681 C CB . LEU A 1 618 ? -88.730 0.464 40.643 1.00 53.42 ? 644 LEU A CB 1 ATOM 4682 C CG . LEU A 1 618 ? -88.372 0.276 42.130 1.00 62.55 ? 644 LEU A CG 1 ATOM 4683 C CD1 . LEU A 1 618 ? -87.001 0.857 42.461 1.00 65.58 ? 644 LEU A CD1 1 ATOM 4684 C CD2 . LEU A 1 618 ? -89.420 0.886 43.057 1.00 58.25 ? 644 LEU A CD2 1 ATOM 4685 N N . ASP A 1 619 ? -86.456 -2.099 40.213 1.00 56.50 ? 645 ASP A N 1 ATOM 4686 C CA . ASP A 1 619 ? -86.239 -3.522 40.476 1.00 56.39 ? 645 ASP A CA 1 ATOM 4687 C C . ASP A 1 619 ? -86.066 -3.759 41.977 1.00 58.76 ? 645 ASP A C 1 ATOM 4688 O O . ASP A 1 619 ? -85.099 -3.281 42.580 1.00 59.81 ? 645 ASP A O 1 ATOM 4689 C CB . ASP A 1 619 ? -85.016 -4.036 39.710 1.00 50.98 ? 645 ASP A CB 1 ATOM 4690 C CG . ASP A 1 619 ? -84.743 -5.497 39.971 1.00 57.99 ? 645 ASP A CG 1 ATOM 4691 O OD1 . ASP A 1 619 ? -85.344 -6.066 40.926 1.00 59.33 ? 645 ASP A OD1 1 ATOM 4692 O OD2 . ASP A 1 619 ? -83.883 -6.063 39.260 1.00 57.40 ? 645 ASP A OD2 1 ATOM 4693 N N . LEU A 1 620 ? -87.021 -4.471 42.572 1.00 52.79 ? 646 LEU A N 1 ATOM 4694 C CA . LEU A 1 620 ? -86.981 -4.789 43.993 1.00 46.31 ? 646 LEU A CA 1 ATOM 4695 C C . LEU A 1 620 ? -86.833 -6.280 44.213 1.00 45.82 ? 646 LEU A C 1 ATOM 4696 O O . LEU A 1 620 ? -87.224 -6.800 45.255 1.00 53.77 ? 646 LEU A O 1 ATOM 4697 C CB . LEU A 1 620 ? -88.237 -4.319 44.712 1.00 48.39 ? 646 LEU A CB 1 ATOM 4698 C CG . LEU A 1 620 ? -88.573 -2.845 44.521 1.00 54.03 ? 646 LEU A CG 1 ATOM 4699 C CD1 . LEU A 1 620 ? -89.799 -2.501 45.349 1.00 55.68 ? 646 LEU A CD1 1 ATOM 4700 C CD2 . LEU A 1 620 ? -87.418 -1.947 44.910 1.00 58.96 ? 646 LEU A CD2 1 ATOM 4701 N N . SER A 1 621 ? -86.246 -6.977 43.258 1.00 42.23 ? 647 SER A N 1 ATOM 4702 C CA . SER A 1 621 ? -86.087 -8.409 43.418 1.00 45.70 ? 647 SER A CA 1 ATOM 4703 C C . SER A 1 621 ? -85.054 -8.749 44.478 1.00 48.99 ? 647 SER A C 1 ATOM 4704 O O . SER A 1 621 ? -84.361 -7.880 44.959 1.00 51.30 ? 647 SER A O 1 ATOM 4705 C CB . SER A 1 621 ? -85.725 -9.034 42.082 1.00 46.34 ? 647 SER A CB 1 ATOM 4706 O OG . SER A 1 621 ? -84.674 -8.306 41.465 1.00 46.08 ? 647 SER A OG 1 ATOM 4707 N N . LEU A 1 622 ? -85.016 -10.010 44.890 1.00 52.38 ? 648 LEU A N 1 ATOM 4708 C CA . LEU A 1 622 ? -84.059 -10.466 45.887 1.00 50.52 ? 648 LEU A CA 1 ATOM 4709 C C . LEU A 1 622 ? -83.889 -9.552 47.119 1.00 47.26 ? 648 LEU A C 1 ATOM 4710 O O . LEU A 1 622 ? -82.802 -9.111 47.404 1.00 50.85 ? 648 LEU A O 1 ATOM 4711 C CB . LEU A 1 622 ? -82.718 -10.698 45.212 1.00 47.47 ? 648 LEU A CB 1 ATOM 4712 C CG . LEU A 1 622 ? -82.679 -11.888 44.275 1.00 50.01 ? 648 LEU A CG 1 ATOM 4713 C CD1 . LEU A 1 622 ? -81.429 -11.940 43.426 1.00 50.16 ? 648 LEU A CD1 1 ATOM 4714 C CD2 . LEU A 1 622 ? -82.761 -13.146 45.101 1.00 55.64 ? 648 LEU A CD2 1 ATOM 4715 N N . ASN A 1 623 ? -84.985 -9.147 47.734 1.00 46.18 ? 649 ASN A N 1 ATOM 4716 C CA . ASN A 1 623 ? -84.933 -8.346 48.952 1.00 49.22 ? 649 ASN A CA 1 ATOM 4717 C C . ASN A 1 623 ? -85.579 -9.071 50.139 1.00 49.78 ? 649 ASN A C 1 ATOM 4718 O O . ASN A 1 623 ? -85.875 -8.457 51.174 1.00 53.31 ? 649 ASN A O 1 ATOM 4719 C CB . ASN A 1 623 ? -85.582 -6.975 48.795 1.00 54.98 ? 649 ASN A CB 1 ATOM 4720 C CG . ASN A 1 623 ? -84.661 -5.947 48.187 1.00 59.57 ? 649 ASN A CG 1 ATOM 4721 O OD1 . ASN A 1 623 ? -84.274 -5.014 48.881 1.00 58.03 ? 649 ASN A OD1 1 ATOM 4722 N ND2 . ASN A 1 623 ? -84.181 -6.185 46.983 1.00 66.48 ? 649 ASN A ND2 1 ATOM 4723 N N . ARG A 1 624 ? -85.842 -10.358 49.965 1.00 47.56 ? 650 ARG A N 1 ATOM 4724 C CA . ARG A 1 624 ? -86.445 -11.187 51.004 1.00 53.77 ? 650 ARG A CA 1 ATOM 4725 C C . ARG A 1 624 ? -87.767 -10.635 51.510 1.00 56.77 ? 650 ARG A C 1 ATOM 4726 O O . ARG A 1 624 ? -88.065 -10.705 52.692 1.00 61.13 ? 650 ARG A O 1 ATOM 4727 C CB . ARG A 1 624 ? -85.481 -11.336 52.167 1.00 56.02 ? 650 ARG A CB 1 ATOM 4728 C CG . ARG A 1 624 ? -84.128 -11.817 51.728 1.00 64.33 ? 650 ARG A CG 1 ATOM 4729 C CD . ARG A 1 624 ? -83.172 -11.924 52.875 1.00 72.44 ? 650 ARG A CD 1 ATOM 4730 N NE . ARG A 1 624 ? -81.807 -12.116 52.394 1.00 95.32 ? 650 ARG A NE 1 ATOM 4731 C CZ . ARG A 1 624 ? -80.756 -12.308 53.182 1.00 99.21 ? 650 ARG A CZ 1 ATOM 4732 N NH1 . ARG A 1 624 ? -80.925 -12.434 54.490 1.00 105.69 ? 650 ARG A NH1 1 ATOM 4733 N NH2 . ARG A 1 624 ? -79.548 -12.452 52.655 1.00 100.55 ? 650 ARG A NH2 1 ATOM 4734 N N . LEU A 1 625 ? -88.553 -10.045 50.640 1.00 55.66 ? 651 LEU A N 1 ATOM 4735 C CA . LEU A 1 625 ? -89.825 -9.522 51.090 1.00 60.57 ? 651 LEU A CA 1 ATOM 4736 C C . LEU A 1 625 ? -90.863 -10.646 51.279 1.00 65.16 ? 651 LEU A C 1 ATOM 4737 O O . LEU A 1 625 ? -91.038 -11.493 50.395 1.00 62.89 ? 651 LEU A O 1 ATOM 4738 C CB . LEU A 1 625 ? -90.345 -8.484 50.116 1.00 57.25 ? 651 LEU A CB 1 ATOM 4739 C CG . LEU A 1 625 ? -89.566 -7.191 50.097 1.00 62.54 ? 651 LEU A CG 1 ATOM 4740 C CD1 . LEU A 1 625 ? -89.971 -6.354 48.904 1.00 72.71 ? 651 LEU A CD1 1 ATOM 4741 C CD2 . LEU A 1 625 ? -89.784 -6.418 51.386 1.00 66.11 ? 651 LEU A CD2 1 ATOM 4742 N N . LYS A 1 626 ? -91.438 -10.707 52.487 1.00 66.65 ? 652 LYS A N 1 ATOM 4743 C CA . LYS A 1 626 ? -92.478 -11.675 52.837 1.00 62.05 ? 652 LYS A CA 1 ATOM 4744 C C . LYS A 1 626 ? -93.799 -10.915 52.879 1.00 63.25 ? 652 LYS A C 1 ATOM 4745 O O . LYS A 1 626 ? -94.866 -11.489 52.674 1.00 77.95 ? 652 LYS A O 1 ATOM 4746 C CB . LYS A 1 626 ? -92.256 -12.277 54.223 1.00 62.79 ? 652 LYS A CB 1 ATOM 4747 C CG . LYS A 1 626 ? -91.079 -13.222 54.431 1.00 67.36 ? 652 LYS A CG 1 ATOM 4748 C CD . LYS A 1 626 ? -91.057 -13.590 55.917 1.00 70.01 ? 652 LYS A CD 1 ATOM 4749 C CE . LYS A 1 626 ? -89.905 -14.490 56.355 1.00 88.83 ? 652 LYS A CE 1 ATOM 4750 N NZ . LYS A 1 626 ? -89.937 -15.875 55.815 1.00 86.87 ? 652 LYS A NZ 1 ATOM 4751 N N . HIS A 1 627 ? -93.714 -9.608 53.088 1.00 63.38 ? 653 HIS A N 1 ATOM 4752 C CA . HIS A 1 627 ? -94.893 -8.760 53.182 1.00 77.67 ? 653 HIS A CA 1 ATOM 4753 C C . HIS A 1 627 ? -94.537 -7.283 52.937 1.00 80.81 ? 653 HIS A C 1 ATOM 4754 O O . HIS A 1 627 ? -93.572 -6.772 53.487 1.00 84.53 ? 653 HIS A O 1 ATOM 4755 C CB . HIS A 1 627 ? -95.521 -8.950 54.580 1.00 85.98 ? 653 HIS A CB 1 ATOM 4756 C CG . HIS A 1 627 ? -96.659 -8.020 54.879 1.00 115.91 ? 653 HIS A CG 1 ATOM 4757 N ND1 . HIS A 1 627 ? -96.502 -6.867 55.621 1.00 128.81 ? 653 HIS A ND1 1 ATOM 4758 C CD2 . HIS A 1 627 ? -97.969 -8.072 54.540 1.00 123.10 ? 653 HIS A CD2 1 ATOM 4759 C CE1 . HIS A 1 627 ? -97.668 -6.257 55.739 1.00 126.17 ? 653 HIS A CE1 1 ATOM 4760 N NE2 . HIS A 1 627 ? -98.573 -6.962 55.082 1.00 133.67 ? 653 HIS A NE2 1 ATOM 4761 N N . ILE A 1 628 ? -95.327 -6.602 52.119 1.00 75.72 ? 654 ILE A N 1 ATOM 4762 C CA . ILE A 1 628 ? -95.083 -5.202 51.825 1.00 66.45 ? 654 ILE A CA 1 ATOM 4763 C C . ILE A 1 628 ? -96.083 -4.309 52.520 1.00 68.36 ? 654 ILE A C 1 ATOM 4764 O O . ILE A 1 628 ? -97.279 -4.427 52.306 1.00 74.10 ? 654 ILE A O 1 ATOM 4765 C CB . ILE A 1 628 ? -95.189 -4.933 50.322 1.00 67.25 ? 654 ILE A CB 1 ATOM 4766 C CG1 . ILE A 1 628 ? -94.208 -5.832 49.573 1.00 69.74 ? 654 ILE A CG1 1 ATOM 4767 C CG2 . ILE A 1 628 ? -94.942 -3.452 50.029 1.00 73.60 ? 654 ILE A CG2 1 ATOM 4768 C CD1 . ILE A 1 628 ? -94.209 -5.632 48.078 1.00 81.46 ? 654 ILE A CD1 1 ATOM 4769 N N . PRO A 1 629 ? -95.604 -3.386 53.346 1.00 79.96 ? 655 PRO A N 1 ATOM 4770 C CA . PRO A 1 629 ? -96.621 -2.560 53.965 1.00 76.51 ? 655 PRO A CA 1 ATOM 4771 C C . PRO A 1 629 ? -97.392 -1.815 52.899 1.00 74.24 ? 655 PRO A C 1 ATOM 4772 O O . PRO A 1 629 ? -96.803 -1.319 51.927 1.00 70.63 ? 655 PRO A O 1 ATOM 4773 C CB . PRO A 1 629 ? -95.813 -1.613 54.851 1.00 75.16 ? 655 PRO A CB 1 ATOM 4774 C CG . PRO A 1 629 ? -94.604 -2.413 55.220 1.00 77.36 ? 655 PRO A CG 1 ATOM 4775 C CD . PRO A 1 629 ? -94.296 -3.259 54.014 1.00 82.59 ? 655 PRO A CD 1 ATOM 4776 N N . ASN A 1 630 ? -98.706 -1.779 53.055 1.00 78.60 ? 656 ASN A N 1 ATOM 4777 C CA . ASN A 1 630 ? -99.564 -1.109 52.087 1.00 83.53 ? 656 ASN A CA 1 ATOM 4778 C C . ASN A 1 630 ? -99.153 0.325 51.829 1.00 73.65 ? 656 ASN A C 1 ATOM 4779 O O . ASN A 1 630 ? -99.117 0.745 50.677 1.00 86.03 ? 656 ASN A O 1 ATOM 4780 C CB . ASN A 1 630 ? -101.057 -1.229 52.475 1.00 78.43 ? 656 ASN A CB 1 ATOM 4781 C CG . ASN A 1 630 ? -101.591 -2.660 52.329 1.00 79.64 ? 656 ASN A CG 1 ATOM 4782 O OD1 . ASN A 1 630 ? -101.163 -3.424 51.456 1.00 77.73 ? 656 ASN A OD1 1 ATOM 4783 N ND2 . ASN A 1 630 ? -102.561 -3.002 53.145 1.00 86.87 ? 656 ASN A ND2 1 ATOM 4784 N N . GLU A 1 631 ? -98.783 1.068 52.868 1.00 72.39 ? 657 GLU A N 1 ATOM 4785 C CA . GLU A 1 631 ? -98.377 2.455 52.641 1.00 79.08 ? 657 GLU A CA 1 ATOM 4786 C C . GLU A 1 631 ? -96.968 2.490 51.986 1.00 78.74 ? 657 GLU A C 1 ATOM 4787 O O . GLU A 1 631 ? -96.560 3.501 51.377 1.00 74.19 ? 657 GLU A O 1 ATOM 4788 C CB . GLU A 1 631 ? -98.391 3.284 53.931 1.00 82.00 ? 657 GLU A CB 1 ATOM 4789 C CG . GLU A 1 631 ? -98.187 4.778 53.648 1.00 101.99 ? 657 GLU A CG 1 ATOM 4790 C CD . GLU A 1 631 ? -97.935 5.625 54.887 1.00 110.99 ? 657 GLU A CD 1 ATOM 4791 O OE1 . GLU A 1 631 ? -97.773 5.059 55.988 1.00 114.45 ? 657 GLU A OE1 1 ATOM 4792 O OE2 . GLU A 1 631 ? -97.811 6.863 54.736 1.00 112.20 ? 657 GLU A OE2 1 ATOM 4793 N N . ALA A 1 632 ? -96.216 1.404 52.139 1.00 69.82 ? 658 ALA A N 1 ATOM 4794 C CA . ALA A 1 632 ? -94.892 1.332 51.556 1.00 79.96 ? 658 ALA A CA 1 ATOM 4795 C C . ALA A 1 632 ? -95.060 1.282 50.049 1.00 83.91 ? 658 ALA A C 1 ATOM 4796 O O . ALA A 1 632 ? -94.422 2.039 49.305 1.00 86.21 ? 658 ALA A O 1 ATOM 4797 C CB . ALA A 1 632 ? -94.156 0.100 52.048 1.00 82.87 ? 658 ALA A CB 1 ATOM 4798 N N . PHE A 1 633 ? -95.972 0.421 49.617 1.00 74.97 ? 659 PHE A N 1 ATOM 4799 C CA . PHE A 1 633 ? -96.258 0.249 48.204 1.00 76.96 ? 659 PHE A CA 1 ATOM 4800 C C . PHE A 1 633 ? -96.862 1.528 47.602 1.00 70.57 ? 659 PHE A C 1 ATOM 4801 O O . PHE A 1 633 ? -96.457 1.947 46.537 1.00 77.15 ? 659 PHE A O 1 ATOM 4802 C CB . PHE A 1 633 ? -97.206 -0.928 48.012 1.00 66.56 ? 659 PHE A CB 1 ATOM 4803 C CG . PHE A 1 633 ? -97.355 -1.357 46.593 1.00 73.29 ? 659 PHE A CG 1 ATOM 4804 C CD1 . PHE A 1 633 ? -98.224 -0.703 45.741 1.00 83.08 ? 659 PHE A CD1 1 ATOM 4805 C CD2 . PHE A 1 633 ? -96.705 -2.490 46.137 1.00 79.59 ? 659 PHE A CD2 1 ATOM 4806 C CE1 . PHE A 1 633 ? -98.399 -1.140 44.440 1.00 82.51 ? 659 PHE A CE1 1 ATOM 4807 C CE2 . PHE A 1 633 ? -96.861 -2.924 44.832 1.00 77.86 ? 659 PHE A CE2 1 ATOM 4808 C CZ . PHE A 1 633 ? -97.709 -2.250 43.985 1.00 84.43 ? 659 PHE A CZ 1 ATOM 4809 N N . LEU A 1 634 ? -97.802 2.162 48.298 1.00 68.33 ? 660 LEU A N 1 ATOM 4810 C CA . LEU A 1 634 ? -98.428 3.389 47.786 1.00 70.24 ? 660 LEU A CA 1 ATOM 4811 C C . LEU A 1 634 ? -97.465 4.513 47.612 1.00 73.55 ? 660 LEU A C 1 ATOM 4812 O O . LEU A 1 634 ? -97.751 5.444 46.856 1.00 81.35 ? 660 LEU A O 1 ATOM 4813 C CB . LEU A 1 634 ? -99.569 3.887 48.681 1.00 81.83 ? 660 LEU A CB 1 ATOM 4814 C CG . LEU A 1 634 ? -100.866 3.087 48.751 1.00 79.44 ? 660 LEU A CG 1 ATOM 4815 C CD1 . LEU A 1 634 ? -101.812 3.725 49.750 1.00 79.16 ? 660 LEU A CD1 1 ATOM 4816 C CD2 . LEU A 1 634 ? -101.505 3.044 47.385 1.00 76.28 ? 660 LEU A CD2 1 ATOM 4817 N N . ASN A 1 635 ? -96.369 4.492 48.370 1.00 75.08 ? 661 ASN A N 1 ATOM 4818 C CA . ASN A 1 635 ? -95.367 5.551 48.260 1.00 68.48 ? 661 ASN A CA 1 ATOM 4819 C C . ASN A 1 635 ? -94.325 5.359 47.152 1.00 66.67 ? 661 ASN A C 1 ATOM 4820 O O . ASN A 1 635 ? -93.463 6.221 46.963 1.00 63.91 ? 661 ASN A O 1 ATOM 4821 C CB . ASN A 1 635 ? -94.743 5.879 49.617 1.00 82.88 ? 661 ASN A CB 1 ATOM 4822 C CG . ASN A 1 635 ? -95.671 6.703 50.501 1.00 81.35 ? 661 ASN A CG 1 ATOM 4823 O OD1 . ASN A 1 635 ? -96.490 7.473 50.001 1.00 88.43 ? 661 ASN A OD1 1 ATOM 4824 N ND2 . ASN A 1 635 ? -95.430 6.673 51.798 1.00 79.35 ? 661 ASN A ND2 1 ATOM 4825 N N . LEU A 1 636 ? -94.418 4.247 46.409 1.00 65.83 ? 662 LEU A N 1 ATOM 4826 C CA . LEU A 1 636 ? -93.509 4.007 45.288 1.00 63.88 ? 662 LEU A CA 1 ATOM 4827 C C . LEU A 1 636 ? -93.947 5.056 44.282 1.00 65.33 ? 662 LEU A C 1 ATOM 4828 O O . LEU A 1 636 ? -95.123 5.380 44.225 1.00 76.40 ? 662 LEU A O 1 ATOM 4829 C CB . LEU A 1 636 ? -93.690 2.608 44.690 1.00 59.92 ? 662 LEU A CB 1 ATOM 4830 C CG . LEU A 1 636 ? -93.459 1.415 45.622 1.00 61.23 ? 662 LEU A CG 1 ATOM 4831 C CD1 . LEU A 1 636 ? -93.741 0.093 44.923 1.00 55.22 ? 662 LEU A CD1 1 ATOM 4832 C CD2 . LEU A 1 636 ? -92.039 1.428 46.170 1.00 70.99 ? 662 LEU A CD2 1 ATOM 4833 N N . PRO A 1 637 ? -93.021 5.579 43.477 1.00 72.97 ? 663 PRO A N 1 ATOM 4834 C CA . PRO A 1 637 ? -93.392 6.621 42.514 1.00 70.18 ? 663 PRO A CA 1 ATOM 4835 C C . PRO A 1 637 ? -94.547 6.261 41.583 1.00 74.09 ? 663 PRO A C 1 ATOM 4836 O O . PRO A 1 637 ? -94.536 5.209 40.931 1.00 74.96 ? 663 PRO A O 1 ATOM 4837 C CB . PRO A 1 637 ? -92.106 6.841 41.711 1.00 69.52 ? 663 PRO A CB 1 ATOM 4838 C CG . PRO A 1 637 ? -91.027 6.174 42.490 1.00 72.16 ? 663 PRO A CG 1 ATOM 4839 C CD . PRO A 1 637 ? -91.690 5.031 43.188 1.00 69.35 ? 663 PRO A CD 1 ATOM 4840 N N . ALA A 1 638 ? -95.523 7.161 41.505 1.00 83.57 ? 664 ALA A N 1 ATOM 4841 C CA . ALA A 1 638 ? -96.702 6.969 40.659 1.00 84.83 ? 664 ALA A CA 1 ATOM 4842 C C . ALA A 1 638 ? -96.302 6.950 39.181 1.00 90.33 ? 664 ALA A C 1 ATOM 4843 O O . ALA A 1 638 ? -97.025 6.395 38.323 1.00 93.43 ? 664 ALA A O 1 ATOM 4844 C CB . ALA A 1 638 ? -97.709 8.066 40.927 1.00 73.77 ? 664 ALA A CB 1 ATOM 4845 N N . SER A 1 639 ? -95.126 7.522 38.904 1.00 74.19 ? 665 SER A N 1 ATOM 4846 C CA . SER A 1 639 ? -94.583 7.582 37.553 1.00 64.22 ? 665 SER A CA 1 ATOM 4847 C C . SER A 1 639 ? -94.106 6.244 37.015 1.00 64.83 ? 665 SER A C 1 ATOM 4848 O O . SER A 1 639 ? -93.777 6.143 35.830 1.00 68.90 ? 665 SER A O 1 ATOM 4849 C CB . SER A 1 639 ? -93.441 8.603 37.479 1.00 66.35 ? 665 SER A CB 1 ATOM 4850 O OG . SER A 1 639 ? -92.426 8.354 38.443 1.00 77.15 ? 665 SER A OG 1 ATOM 4851 N N . LEU A 1 640 ? -94.094 5.207 37.848 1.00 63.06 ? 666 LEU A N 1 ATOM 4852 C CA . LEU A 1 640 ? -93.625 3.901 37.378 1.00 71.85 ? 666 LEU A CA 1 ATOM 4853 C C . LEU A 1 640 ? -94.389 3.321 36.203 1.00 71.91 ? 666 LEU A C 1 ATOM 4854 O O . LEU A 1 640 ? -95.614 3.379 36.145 1.00 81.66 ? 666 LEU A O 1 ATOM 4855 C CB . LEU A 1 640 ? -93.624 2.850 38.498 1.00 72.73 ? 666 LEU A CB 1 ATOM 4856 C CG . LEU A 1 640 ? -92.644 3.038 39.658 1.00 78.60 ? 666 LEU A CG 1 ATOM 4857 C CD1 . LEU A 1 640 ? -92.760 1.846 40.590 1.00 81.34 ? 666 LEU A CD1 1 ATOM 4858 C CD2 . LEU A 1 640 ? -91.212 3.171 39.159 1.00 79.73 ? 666 LEU A CD2 1 ATOM 4859 N N . THR A 1 641 ? -93.630 2.721 35.296 1.00 71.66 ? 667 THR A N 1 ATOM 4860 C CA . THR A 1 641 ? -94.166 2.061 34.125 1.00 68.16 ? 667 THR A CA 1 ATOM 4861 C C . THR A 1 641 ? -93.736 0.601 34.196 1.00 62.91 ? 667 THR A C 1 ATOM 4862 O O . THR A 1 641 ? -94.316 -0.251 33.554 1.00 74.78 ? 667 THR A O 1 ATOM 4863 C CB . THR A 1 641 ? -93.593 2.633 32.814 1.00 67.87 ? 667 THR A CB 1 ATOM 4864 O OG1 . THR A 1 641 ? -92.252 2.174 32.627 1.00 84.78 ? 667 THR A OG1 1 ATOM 4865 C CG2 . THR A 1 641 ? -93.636 4.164 32.823 1.00 71.83 ? 667 THR A CG2 1 ATOM 4866 N N . GLU A 1 642 ? -92.703 0.317 34.975 1.00 65.56 ? 668 GLU A N 1 ATOM 4867 C CA . GLU A 1 642 ? -92.201 -1.037 35.099 1.00 64.29 ? 668 GLU A CA 1 ATOM 4868 C C . GLU A 1 642 ? -91.758 -1.316 36.543 1.00 62.50 ? 668 GLU A C 1 ATOM 4869 O O . GLU A 1 642 ? -91.060 -0.520 37.151 1.00 67.70 ? 668 GLU A O 1 ATOM 4870 C CB . GLU A 1 642 ? -91.073 -1.198 34.119 1.00 62.39 ? 668 GLU A CB 1 ATOM 4871 C CG . GLU A 1 642 ? -90.447 -2.565 34.123 1.00 79.99 ? 668 GLU A CG 1 ATOM 4872 C CD . GLU A 1 642 ? -89.393 -2.686 33.048 1.00 81.45 ? 668 GLU A CD 1 ATOM 4873 O OE1 . GLU A 1 642 ? -89.284 -1.739 32.224 1.00 67.76 ? 668 GLU A OE1 1 ATOM 4874 O OE2 . GLU A 1 642 ? -88.706 -3.732 33.008 1.00 89.10 ? 668 GLU A OE2 1 ATOM 4875 N N . LEU A 1 643 ? -92.266 -2.387 37.124 1.00 66.50 ? 669 LEU A N 1 ATOM 4876 C CA . LEU A 1 643 ? -91.931 -2.744 38.484 1.00 59.00 ? 669 LEU A CA 1 ATOM 4877 C C . LEU A 1 643 ? -91.637 -4.205 38.616 1.00 64.40 ? 669 LEU A C 1 ATOM 4878 O O . LEU A 1 643 ? -92.463 -5.014 38.303 1.00 61.25 ? 669 LEU A O 1 ATOM 4879 C CB . LEU A 1 643 ? -93.082 -2.402 39.396 1.00 57.24 ? 669 LEU A CB 1 ATOM 4880 C CG . LEU A 1 643 ? -92.958 -2.812 40.844 1.00 65.12 ? 669 LEU A CG 1 ATOM 4881 C CD1 . LEU A 1 643 ? -91.680 -2.280 41.425 1.00 71.16 ? 669 LEU A CD1 1 ATOM 4882 C CD2 . LEU A 1 643 ? -94.111 -2.239 41.614 1.00 68.17 ? 669 LEU A CD2 1 ATOM 4883 N N . HIS A 1 644 ? -90.479 -4.535 39.158 1.00 63.22 ? 670 HIS A N 1 ATOM 4884 C CA . HIS A 1 644 ? -90.108 -5.904 39.358 1.00 61.44 ? 670 HIS A CA 1 ATOM 4885 C C . HIS A 1 644 ? -90.019 -6.171 40.806 1.00 59.34 ? 670 HIS A C 1 ATOM 4886 O O . HIS A 1 644 ? -89.433 -5.408 41.546 1.00 58.24 ? 670 HIS A O 1 ATOM 4887 C CB . HIS A 1 644 ? -88.764 -6.179 38.744 1.00 63.46 ? 670 HIS A CB 1 ATOM 4888 C CG . HIS A 1 644 ? -88.731 -6.046 37.256 1.00 67.65 ? 670 HIS A CG 1 ATOM 4889 N ND1 . HIS A 1 644 ? -88.686 -7.093 36.453 1.00 71.57 ? 670 HIS A ND1 1 ATOM 4890 C CD2 . HIS A 1 644 ? -88.710 -4.941 36.448 1.00 64.51 ? 670 HIS A CD2 1 ATOM 4891 C CE1 . HIS A 1 644 ? -88.655 -6.688 35.192 1.00 68.46 ? 670 HIS A CE1 1 ATOM 4892 N NE2 . HIS A 1 644 ? -88.671 -5.368 35.190 1.00 60.04 ? 670 HIS A NE2 1 ATOM 4893 N N . ILE A 1 645 ? -90.654 -7.233 41.242 1.00 59.56 ? 671 ILE A N 1 ATOM 4894 C CA . ILE A 1 645 ? -90.581 -7.657 42.608 1.00 52.78 ? 671 ILE A CA 1 ATOM 4895 C C . ILE A 1 645 ? -90.332 -9.132 42.662 1.00 50.64 ? 671 ILE A C 1 ATOM 4896 O O . ILE A 1 645 ? -90.706 -9.772 43.603 1.00 59.78 ? 671 ILE A O 1 ATOM 4897 C CB . ILE A 1 645 ? -91.868 -7.348 43.352 1.00 55.83 ? 671 ILE A CB 1 ATOM 4898 C CG1 . ILE A 1 645 ? -92.264 -5.911 43.141 1.00 69.59 ? 671 ILE A CG1 1 ATOM 4899 C CG2 . ILE A 1 645 ? -91.681 -7.566 44.822 1.00 65.74 ? 671 ILE A CG2 1 ATOM 4900 C CD1 . ILE A 1 645 ? -93.572 -5.574 43.792 1.00 69.03 ? 671 ILE A CD1 1 ATOM 4901 N N . ASN A 1 646 ? -89.720 -9.679 41.638 1.00 43.89 ? 672 ASN A N 1 ATOM 4902 C CA . ASN A 1 646 ? -89.580 -11.107 41.548 1.00 48.33 ? 672 ASN A CA 1 ATOM 4903 C C . ASN A 1 646 ? -88.627 -11.648 42.555 1.00 56.75 ? 672 ASN A C 1 ATOM 4904 O O . ASN A 1 646 ? -87.875 -10.932 43.145 1.00 56.38 ? 672 ASN A O 1 ATOM 4905 C CB . ASN A 1 646 ? -89.124 -11.523 40.178 1.00 52.34 ? 672 ASN A CB 1 ATOM 4906 C CG . ASN A 1 646 ? -87.986 -10.712 39.683 1.00 44.81 ? 672 ASN A CG 1 ATOM 4907 O OD1 . ASN A 1 646 ? -88.062 -9.521 39.640 1.00 58.43 ? 672 ASN A OD1 1 ATOM 4908 N ND2 . ASN A 1 646 ? -86.936 -11.359 39.291 1.00 53.20 ? 672 ASN A ND2 1 ATOM 4909 N N . ASP A 1 647 ? -88.716 -12.935 42.787 1.00 60.92 ? 673 ASP A N 1 ATOM 4910 C CA . ASP A 1 647 ? -87.751 -13.617 43.591 1.00 60.99 ? 673 ASP A CA 1 ATOM 4911 C C . ASP A 1 647 ? -87.645 -13.072 44.973 1.00 67.28 ? 673 ASP A C 1 ATOM 4912 O O . ASP A 1 647 ? -86.583 -12.882 45.495 1.00 69.08 ? 673 ASP A O 1 ATOM 4913 C CB . ASP A 1 647 ? -86.432 -13.620 42.890 1.00 67.03 ? 673 ASP A CB 1 ATOM 4914 C CG . ASP A 1 647 ? -86.412 -14.591 41.777 1.00 73.00 ? 673 ASP A CG 1 ATOM 4915 O OD1 . ASP A 1 647 ? -87.098 -15.601 41.874 1.00 74.16 ? 673 ASP A OD1 1 ATOM 4916 O OD2 . ASP A 1 647 ? -85.726 -14.361 40.791 1.00 95.64 ? 673 ASP A OD2 1 ATOM 4917 N N . ASN A 1 648 ? -88.792 -12.813 45.551 1.00 65.22 ? 674 ASN A N 1 ATOM 4918 C CA . ASN A 1 648 ? -88.914 -12.526 46.933 1.00 56.89 ? 674 ASN A CA 1 ATOM 4919 C C . ASN A 1 648 ? -89.640 -13.694 47.518 1.00 59.19 ? 674 ASN A C 1 ATOM 4920 O O . ASN A 1 648 ? -89.504 -14.782 47.023 1.00 65.45 ? 674 ASN A O 1 ATOM 4921 C CB . ASN A 1 648 ? -89.695 -11.267 47.107 1.00 59.38 ? 674 ASN A CB 1 ATOM 4922 C CG . ASN A 1 648 ? -88.830 -10.057 47.032 1.00 67.60 ? 674 ASN A CG 1 ATOM 4923 O OD1 . ASN A 1 648 ? -88.107 -9.757 47.943 1.00 70.85 ? 674 ASN A OD1 1 ATOM 4924 N ND2 . ASN A 1 648 ? -88.899 -9.368 45.944 1.00 71.50 ? 674 ASN A ND2 1 ATOM 4925 N N . MET A 1 649 ? -90.356 -13.493 48.606 1.00 63.85 ? 675 MET A N 1 ATOM 4926 C CA . MET A 1 649 ? -91.171 -14.553 49.173 1.00 70.67 ? 675 MET A CA 1 ATOM 4927 C C . MET A 1 649 ? -92.576 -14.125 49.544 1.00 58.25 ? 675 MET A C 1 ATOM 4928 O O . MET A 1 649 ? -93.080 -14.501 50.560 1.00 65.83 ? 675 MET A O 1 ATOM 4929 C CB . MET A 1 649 ? -90.471 -15.175 50.363 1.00 74.28 ? 675 MET A CB 1 ATOM 4930 C CG . MET A 1 649 ? -88.977 -15.231 50.201 1.00 85.63 ? 675 MET A CG 1 ATOM 4931 S SD . MET A 1 649 ? -88.156 -15.182 51.783 1.00 99.00 ? 675 MET A SD 1 ATOM 4932 C CE . MET A 1 649 ? -88.015 -16.930 52.079 1.00 110.53 ? 675 MET A CE 1 ATOM 4933 N N . LEU A 1 650 ? -93.195 -13.311 48.726 1.00 54.91 ? 676 LEU A N 1 ATOM 4934 C CA . LEU A 1 650 ? -94.521 -12.758 49.015 1.00 65.13 ? 676 LEU A CA 1 ATOM 4935 C C . LEU A 1 650 ? -95.615 -13.797 48.855 1.00 67.70 ? 676 LEU A C 1 ATOM 4936 O O . LEU A 1 650 ? -95.549 -14.620 47.941 1.00 59.16 ? 676 LEU A O 1 ATOM 4937 C CB . LEU A 1 650 ? -94.833 -11.620 48.052 1.00 67.06 ? 676 LEU A CB 1 ATOM 4938 C CG . LEU A 1 650 ? -93.885 -10.435 48.056 1.00 67.01 ? 676 LEU A CG 1 ATOM 4939 C CD1 . LEU A 1 650 ? -94.284 -9.467 46.963 1.00 65.42 ? 676 LEU A CD1 1 ATOM 4940 C CD2 . LEU A 1 650 ? -93.916 -9.760 49.413 1.00 70.22 ? 676 LEU A CD2 1 ATOM 4941 N N . LYS A 1 651 ? -96.592 -13.769 49.766 1.00 66.38 ? 677 LYS A N 1 ATOM 4942 C CA . LYS A 1 651 ? -97.748 -14.682 49.730 1.00 70.39 ? 677 LYS A CA 1 ATOM 4943 C C . LYS A 1 651 ? -99.046 -13.974 49.359 1.00 66.25 ? 677 LYS A C 1 ATOM 4944 O O . LYS A 1 651 ? -99.982 -14.600 48.870 1.00 74.22 ? 677 LYS A O 1 ATOM 4945 C CB . LYS A 1 651 ? -97.920 -15.439 51.039 1.00 68.19 ? 677 LYS A CB 1 ATOM 4946 C CG . LYS A 1 651 ? -96.964 -16.605 51.199 1.00 69.37 ? 677 LYS A CG 1 ATOM 4947 C CD . LYS A 1 651 ? -97.189 -17.278 52.537 1.00 70.24 ? 677 LYS A CD 1 ATOM 4948 C CE . LYS A 1 651 ? -96.277 -18.475 52.739 1.00 73.26 ? 677 LYS A CE 1 ATOM 4949 N NZ . LYS A 1 651 ? -96.395 -18.955 54.147 1.00 80.25 ? 677 LYS A NZ 1 ATOM 4950 N N . PHE A 1 652 ? -99.101 -12.675 49.597 1.00 65.06 ? 678 PHE A N 1 ATOM 4951 C CA . PHE A 1 652 ? -100.273 -11.904 49.270 1.00 75.38 ? 678 PHE A CA 1 ATOM 4952 C C . PHE A 1 652 ? -99.795 -10.628 48.592 1.00 73.03 ? 678 PHE A C 1 ATOM 4953 O O . PHE A 1 652 ? -98.637 -10.258 48.714 1.00 77.04 ? 678 PHE A O 1 ATOM 4954 C CB . PHE A 1 652 ? -101.121 -11.604 50.529 1.00 75.37 ? 678 PHE A CB 1 ATOM 4955 C CG . PHE A 1 652 ? -101.480 -12.845 51.329 1.00 99.50 ? 678 PHE A CG 1 ATOM 4956 C CD1 . PHE A 1 652 ? -102.504 -13.698 50.919 1.00 108.52 ? 678 PHE A CD1 1 ATOM 4957 C CD2 . PHE A 1 652 ? -100.808 -13.149 52.515 1.00 127.96 ? 678 PHE A CD2 1 ATOM 4958 C CE1 . PHE A 1 652 ? -102.817 -14.850 51.642 1.00 117.48 ? 678 PHE A CE1 1 ATOM 4959 C CE2 . PHE A 1 652 ? -101.132 -14.288 53.253 1.00 132.10 ? 678 PHE A CE2 1 ATOM 4960 C CZ . PHE A 1 652 ? -102.135 -15.140 52.813 1.00 125.63 ? 678 PHE A CZ 1 ATOM 4961 N N . PHE A 1 653 ? -100.652 -10.046 47.766 1.00 76.23 ? 679 PHE A N 1 ATOM 4962 C CA . PHE A 1 653 ? -100.340 -8.815 47.062 1.00 70.40 ? 679 PHE A CA 1 ATOM 4963 C C . PHE A 1 653 ? -101.657 -8.046 46.966 1.00 68.54 ? 679 PHE A C 1 ATOM 4964 O O . PHE A 1 653 ? -102.629 -8.556 46.429 1.00 82.76 ? 679 PHE A O 1 ATOM 4965 C CB . PHE A 1 653 ? -99.724 -9.116 45.684 1.00 72.94 ? 679 PHE A CB 1 ATOM 4966 C CG . PHE A 1 653 ? -99.366 -7.881 44.901 1.00 78.30 ? 679 PHE A CG 1 ATOM 4967 C CD1 . PHE A 1 653 ? -98.179 -7.224 45.131 1.00 77.37 ? 679 PHE A CD1 1 ATOM 4968 C CD2 . PHE A 1 653 ? -100.216 -7.382 43.931 1.00 85.79 ? 679 PHE A CD2 1 ATOM 4969 C CE1 . PHE A 1 653 ? -97.859 -6.058 44.447 1.00 78.68 ? 679 PHE A CE1 1 ATOM 4970 C CE2 . PHE A 1 653 ? -99.892 -6.230 43.224 1.00 86.50 ? 679 PHE A CE2 1 ATOM 4971 C CZ . PHE A 1 653 ? -98.710 -5.567 43.481 1.00 79.41 ? 679 PHE A CZ 1 ATOM 4972 N N . ASN A 1 654 ? -101.710 -6.867 47.579 1.00 73.48 ? 680 ASN A N 1 ATOM 4973 C CA . ASN A 1 654 ? -102.923 -6.054 47.593 1.00 68.21 ? 680 ASN A CA 1 ATOM 4974 C C . ASN A 1 654 ? -103.071 -5.350 46.245 1.00 66.17 ? 680 ASN A C 1 ATOM 4975 O O . ASN A 1 654 ? -102.688 -4.197 46.076 1.00 71.58 ? 680 ASN A O 1 ATOM 4976 C CB . ASN A 1 654 ? -102.922 -5.088 48.813 1.00 71.04 ? 680 ASN A CB 1 ATOM 4977 C CG . ASN A 1 654 ? -104.260 -4.342 49.015 1.00 85.81 ? 680 ASN A CG 1 ATOM 4978 O OD1 . ASN A 1 654 ? -104.954 -4.040 48.054 1.00 91.77 ? 680 ASN A OD1 1 ATOM 4979 N ND2 . ASN A 1 654 ? -104.572 -3.963 50.279 1.00 78.80 ? 680 ASN A ND2 1 ATOM 4980 N N . TRP A 1 655 ? -103.669 -6.074 45.299 1.00 65.33 ? 681 TRP A N 1 ATOM 4981 C CA . TRP A 1 655 ? -103.914 -5.586 43.927 1.00 73.10 ? 681 TRP A CA 1 ATOM 4982 C C . TRP A 1 655 ? -104.581 -4.222 43.832 1.00 69.12 ? 681 TRP A C 1 ATOM 4983 O O . TRP A 1 655 ? -104.378 -3.479 42.888 1.00 72.57 ? 681 TRP A O 1 ATOM 4984 C CB . TRP A 1 655 ? -104.787 -6.575 43.218 1.00 63.76 ? 681 TRP A CB 1 ATOM 4985 C CG . TRP A 1 655 ? -104.179 -7.862 43.120 1.00 59.69 ? 681 TRP A CG 1 ATOM 4986 C CD1 . TRP A 1 655 ? -104.323 -8.908 43.978 1.00 60.90 ? 681 TRP A CD1 1 ATOM 4987 C CD2 . TRP A 1 655 ? -103.245 -8.271 42.123 1.00 55.50 ? 681 TRP A CD2 1 ATOM 4988 N NE1 . TRP A 1 655 ? -103.562 -9.989 43.539 1.00 67.36 ? 681 TRP A NE1 1 ATOM 4989 C CE2 . TRP A 1 655 ? -102.891 -9.615 42.403 1.00 58.62 ? 681 TRP A CE2 1 ATOM 4990 C CE3 . TRP A 1 655 ? -102.666 -7.632 41.024 1.00 57.19 ? 681 TRP A CE3 1 ATOM 4991 C CZ2 . TRP A 1 655 ? -101.997 -10.325 41.624 1.00 62.15 ? 681 TRP A CZ2 1 ATOM 4992 C CZ3 . TRP A 1 655 ? -101.787 -8.344 40.233 1.00 61.45 ? 681 TRP A CZ3 1 ATOM 4993 C CH2 . TRP A 1 655 ? -101.462 -9.683 40.535 1.00 66.69 ? 681 TRP A CH2 1 ATOM 4994 N N . THR A 1 656 ? -105.449 -3.955 44.780 1.00 68.37 ? 682 THR A N 1 ATOM 4995 C CA . THR A 1 656 ? -106.157 -2.707 44.856 1.00 75.27 ? 682 THR A CA 1 ATOM 4996 C C . THR A 1 656 ? -105.189 -1.540 44.789 1.00 87.39 ? 682 THR A C 1 ATOM 4997 O O . THR A 1 656 ? -105.517 -0.452 44.296 1.00 84.72 ? 682 THR A O 1 ATOM 4998 C CB . THR A 1 656 ? -106.886 -2.629 46.208 1.00 78.00 ? 682 THR A CB 1 ATOM 4999 O OG1 . THR A 1 656 ? -107.651 -3.830 46.404 1.00 76.24 ? 682 THR A OG1 1 ATOM 5000 C CG2 . THR A 1 656 ? -107.771 -1.381 46.300 1.00 78.09 ? 682 THR A CG2 1 ATOM 5001 N N . LEU A 1 657 ? -103.988 -1.767 45.301 1.00 93.38 ? 683 LEU A N 1 ATOM 5002 C CA . LEU A 1 657 ? -102.976 -0.734 45.325 1.00 86.79 ? 683 LEU A CA 1 ATOM 5003 C C . LEU A 1 657 ? -102.587 -0.306 43.927 1.00 80.17 ? 683 LEU A C 1 ATOM 5004 O O . LEU A 1 657 ? -102.178 0.836 43.733 1.00 78.86 ? 683 LEU A O 1 ATOM 5005 C CB . LEU A 1 657 ? -101.777 -1.205 46.135 1.00 97.78 ? 683 LEU A CB 1 ATOM 5006 C CG . LEU A 1 657 ? -102.178 -1.526 47.583 1.00 91.57 ? 683 LEU A CG 1 ATOM 5007 C CD1 . LEU A 1 657 ? -101.044 -2.153 48.373 1.00 92.00 ? 683 LEU A CD1 1 ATOM 5008 C CD2 . LEU A 1 657 ? -102.685 -0.269 48.267 1.00 94.26 ? 683 LEU A CD2 1 ATOM 5009 N N . LEU A 1 658 ? -102.804 -1.174 42.935 1.00 70.22 ? 684 LEU A N 1 ATOM 5010 C CA . LEU A 1 658 ? -102.472 -0.818 41.555 1.00 74.80 ? 684 LEU A CA 1 ATOM 5011 C C . LEU A 1 658 ? -103.214 0.424 41.091 1.00 74.30 ? 684 LEU A C 1 ATOM 5012 O O . LEU A 1 658 ? -102.797 1.072 40.148 1.00 75.74 ? 684 LEU A O 1 ATOM 5013 C CB . LEU A 1 658 ? -102.713 -1.974 40.592 1.00 70.79 ? 684 LEU A CB 1 ATOM 5014 C CG . LEU A 1 658 ? -101.828 -3.200 40.867 1.00 81.16 ? 684 LEU A CG 1 ATOM 5015 C CD1 . LEU A 1 658 ? -102.026 -4.273 39.806 1.00 76.76 ? 684 LEU A CD1 1 ATOM 5016 C CD2 . LEU A 1 658 ? -100.355 -2.815 40.924 1.00 84.89 ? 684 LEU A CD2 1 ATOM 5017 N N . GLN A 1 659 ? -104.284 0.784 41.787 1.00 91.09 ? 685 GLN A N 1 ATOM 5018 C CA . GLN A 1 659 ? -105.055 1.967 41.425 1.00 97.90 ? 685 GLN A CA 1 ATOM 5019 C C . GLN A 1 659 ? -104.269 3.247 41.395 1.00 95.30 ? 685 GLN A C 1 ATOM 5020 O O . GLN A 1 659 ? -104.647 4.164 40.687 1.00 101.32 ? 685 GLN A O 1 ATOM 5021 C CB . GLN A 1 659 ? -106.209 2.181 42.385 1.00 104.99 ? 685 GLN A CB 1 ATOM 5022 C CG . GLN A 1 659 ? -107.294 1.140 42.292 1.00 119.60 ? 685 GLN A CG 1 ATOM 5023 C CD . GLN A 1 659 ? -108.414 1.405 43.270 1.00 122.29 ? 685 GLN A CD 1 ATOM 5024 O OE1 . GLN A 1 659 ? -108.311 2.278 44.132 1.00 118.04 ? 685 GLN A OE1 1 ATOM 5025 N NE2 . GLN A 1 659 ? -109.489 0.646 43.150 1.00 138.25 ? 685 GLN A NE2 1 ATOM 5026 N N . GLN A 1 660 ? -103.199 3.339 42.180 1.00 99.49 ? 686 GLN A N 1 ATOM 5027 C CA . GLN A 1 660 ? -102.413 4.574 42.218 1.00 96.51 ? 686 GLN A CA 1 ATOM 5028 C C . GLN A 1 660 ? -101.311 4.633 41.166 1.00 84.29 ? 686 GLN A C 1 ATOM 5029 O O . GLN A 1 660 ? -100.625 5.637 41.065 1.00 85.46 ? 686 GLN A O 1 ATOM 5030 C CB . GLN A 1 660 ? -101.817 4.793 43.611 1.00 102.50 ? 686 GLN A CB 1 ATOM 5031 C CG . GLN A 1 660 ? -102.849 4.752 44.740 1.00 122.33 ? 686 GLN A CG 1 ATOM 5032 C CD . GLN A 1 660 ? -103.984 5.771 44.610 1.00 123.36 ? 686 GLN A CD 1 ATOM 5033 O OE1 . GLN A 1 660 ? -103.933 6.688 43.796 1.00 120.34 ? 686 GLN A OE1 1 ATOM 5034 N NE2 . GLN A 1 660 ? -105.000 5.627 45.458 1.00 123.61 ? 686 GLN A NE2 1 ATOM 5035 N N . PHE A 1 661 ? -101.213 3.602 40.327 1.00 79.68 ? 687 PHE A N 1 ATOM 5036 C CA . PHE A 1 661 ? -100.184 3.535 39.286 1.00 84.58 ? 687 PHE A CA 1 ATOM 5037 C C . PHE A 1 661 ? -100.761 3.541 37.865 1.00 83.02 ? 687 PHE A C 1 ATOM 5038 O O . PHE A 1 661 ? -100.682 2.551 37.144 1.00 67.61 ? 687 PHE A O 1 ATOM 5039 C CB . PHE A 1 661 ? -99.284 2.330 39.552 1.00 79.55 ? 687 PHE A CB 1 ATOM 5040 C CG . PHE A 1 661 ? -98.559 2.440 40.848 1.00 78.44 ? 687 PHE A CG 1 ATOM 5041 C CD1 . PHE A 1 661 ? -99.090 1.891 41.997 1.00 84.93 ? 687 PHE A CD1 1 ATOM 5042 C CD2 . PHE A 1 661 ? -97.457 3.268 40.955 1.00 81.72 ? 687 PHE A CD2 1 ATOM 5043 C CE1 . PHE A 1 661 ? -98.478 2.087 43.218 1.00 86.33 ? 687 PHE A CE1 1 ATOM 5044 C CE2 . PHE A 1 661 ? -96.832 3.458 42.168 1.00 88.15 ? 687 PHE A CE2 1 ATOM 5045 C CZ . PHE A 1 661 ? -97.347 2.874 43.303 1.00 84.93 ? 687 PHE A CZ 1 ATOM 5046 N N . PRO A 1 662 ? -101.244 4.714 37.433 1.00 82.23 ? 688 PRO A N 1 ATOM 5047 C CA . PRO A 1 662 ? -101.870 4.943 36.132 1.00 78.23 ? 688 PRO A CA 1 ATOM 5048 C C . PRO A 1 662 ? -101.012 4.624 34.920 1.00 86.93 ? 688 PRO A C 1 ATOM 5049 O O . PRO A 1 662 ? -101.559 4.248 33.888 1.00 87.62 ? 688 PRO A O 1 ATOM 5050 C CB . PRO A 1 662 ? -102.202 6.431 36.156 1.00 82.91 ? 688 PRO A CB 1 ATOM 5051 C CG . PRO A 1 662 ? -101.291 7.031 37.169 1.00 84.66 ? 688 PRO A CG 1 ATOM 5052 C CD . PRO A 1 662 ? -101.009 5.969 38.174 1.00 79.91 ? 688 PRO A CD 1 ATOM 5053 N N . ARG A 1 663 ? -99.692 4.792 35.024 1.00 86.25 ? 689 ARG A N 1 ATOM 5054 C CA . ARG A 1 663 ? -98.791 4.505 33.885 1.00 74.61 ? 689 ARG A CA 1 ATOM 5055 C C . ARG A 1 663 ? -98.093 3.142 33.945 1.00 67.39 ? 689 ARG A C 1 ATOM 5056 O O . ARG A 1 663 ? -97.416 2.760 33.003 1.00 58.03 ? 689 ARG A O 1 ATOM 5057 C CB . ARG A 1 663 ? -97.809 5.674 33.643 1.00 69.52 ? 689 ARG A CB 1 ATOM 5058 C CG . ARG A 1 663 ? -98.565 6.906 33.149 1.00 84.49 ? 689 ARG A CG 1 ATOM 5059 C CD . ARG A 1 663 ? -97.755 8.163 32.897 1.00 84.96 ? 689 ARG A CD 1 ATOM 5060 N NE . ARG A 1 663 ? -97.231 8.781 34.116 1.00 103.38 ? 689 ARG A NE 1 ATOM 5061 C CZ . ARG A 1 663 ? -96.616 9.971 34.151 1.00 106.72 ? 689 ARG A CZ 1 ATOM 5062 N NH1 . ARG A 1 663 ? -96.512 10.707 33.048 1.00 100.27 ? 689 ARG A NH1 1 ATOM 5063 N NH2 . ARG A 1 663 ? -96.162 10.463 35.300 1.00 99.83 ? 689 ARG A NH2 1 ATOM 5064 N N . LEU A 1 664 ? -98.443 2.327 34.935 1.00 65.89 ? 690 LEU A N 1 ATOM 5065 C CA . LEU A 1 664 ? -97.817 1.020 35.092 1.00 65.08 ? 690 LEU A CA 1 ATOM 5066 C C . LEU A 1 664 ? -98.143 0.003 34.003 1.00 63.65 ? 690 LEU A C 1 ATOM 5067 O O . LEU A 1 664 ? -99.203 -0.608 34.013 1.00 78.52 ? 690 LEU A O 1 ATOM 5068 C CB . LEU A 1 664 ? -98.177 0.430 36.458 1.00 68.19 ? 690 LEU A CB 1 ATOM 5069 C CG . LEU A 1 664 ? -97.575 -0.949 36.758 1.00 75.82 ? 690 LEU A CG 1 ATOM 5070 C CD1 . LEU A 1 664 ? -96.051 -0.890 36.706 1.00 84.03 ? 690 LEU A CD1 1 ATOM 5071 C CD2 . LEU A 1 664 ? -98.044 -1.471 38.113 1.00 74.87 ? 690 LEU A CD2 1 ATOM 5072 N N . GLU A 1 665 ? -97.176 -0.270 33.142 1.00 70.43 ? 691 GLU A N 1 ATOM 5073 C CA . GLU A 1 665 ? -97.352 -1.249 32.065 1.00 77.88 ? 691 GLU A CA 1 ATOM 5074 C C . GLU A 1 665 ? -96.863 -2.659 32.403 1.00 76.57 ? 691 GLU A C 1 ATOM 5075 O O . GLU A 1 665 ? -97.446 -3.637 31.946 1.00 77.22 ? 691 GLU A O 1 ATOM 5076 C CB . GLU A 1 665 ? -96.609 -0.806 30.811 1.00 75.02 ? 691 GLU A CB 1 ATOM 5077 C CG . GLU A 1 665 ? -97.024 0.559 30.302 1.00 84.57 ? 691 GLU A CG 1 ATOM 5078 C CD . GLU A 1 665 ? -96.363 0.908 28.983 1.00 95.91 ? 691 GLU A CD 1 ATOM 5079 O OE1 . GLU A 1 665 ? -96.110 -0.015 28.171 1.00 109.08 ? 691 GLU A OE1 1 ATOM 5080 O OE2 . GLU A 1 665 ? -96.173 2.111 28.727 1.00 96.11 ? 691 GLU A OE2 1 ATOM 5081 N N . LEU A 1 666 ? -95.747 -2.773 33.122 1.00 71.99 ? 692 LEU A N 1 ATOM 5082 C CA . LEU A 1 666 ? -95.223 -4.091 33.442 1.00 66.85 ? 692 LEU A CA 1 ATOM 5083 C C . LEU A 1 666 ? -95.136 -4.327 34.941 1.00 65.40 ? 692 LEU A C 1 ATOM 5084 O O . LEU A 1 666 ? -94.726 -3.457 35.693 1.00 66.19 ? 692 LEU A O 1 ATOM 5085 C CB . LEU A 1 666 ? -93.861 -4.275 32.792 1.00 67.79 ? 692 LEU A CB 1 ATOM 5086 C CG . LEU A 1 666 ? -93.315 -5.709 32.799 1.00 73.88 ? 692 LEU A CG 1 ATOM 5087 C CD1 . LEU A 1 666 ? -91.989 -5.742 32.077 1.00 75.46 ? 692 LEU A CD1 1 ATOM 5088 C CD2 . LEU A 1 666 ? -93.150 -6.267 34.191 1.00 81.20 ? 692 LEU A CD2 1 ATOM 5089 N N . LEU A 1 667 ? -95.619 -5.483 35.367 1.00 59.02 ? 693 LEU A N 1 ATOM 5090 C CA . LEU A 1 667 ? -95.600 -5.863 36.761 1.00 59.90 ? 693 LEU A CA 1 ATOM 5091 C C . LEU A 1 667 ? -95.063 -7.258 36.821 1.00 60.80 ? 693 LEU A C 1 ATOM 5092 O O . LEU A 1 667 ? -95.624 -8.170 36.225 1.00 59.23 ? 693 LEU A O 1 ATOM 5093 C CB . LEU A 1 667 ? -96.973 -5.765 37.399 1.00 61.40 ? 693 LEU A CB 1 ATOM 5094 C CG . LEU A 1 667 ? -97.072 -6.320 38.825 1.00 68.38 ? 693 LEU A CG 1 ATOM 5095 C CD1 . LEU A 1 667 ? -95.975 -5.791 39.740 1.00 72.65 ? 693 LEU A CD1 1 ATOM 5096 C CD2 . LEU A 1 667 ? -98.442 -6.009 39.402 1.00 72.44 ? 693 LEU A CD2 1 ATOM 5097 N N . ASP A 1 668 ? -93.950 -7.417 37.533 1.00 61.65 ? 694 ASP A N 1 ATOM 5098 C CA . ASP A 1 668 ? -93.291 -8.693 37.621 1.00 57.48 ? 694 ASP A CA 1 ATOM 5099 C C . ASP A 1 668 ? -93.262 -9.241 39.023 1.00 60.31 ? 694 ASP A C 1 ATOM 5100 O O . ASP A 1 668 ? -92.730 -8.618 39.933 1.00 63.50 ? 694 ASP A O 1 ATOM 5101 C CB . ASP A 1 668 ? -91.883 -8.525 37.085 1.00 56.91 ? 694 ASP A CB 1 ATOM 5102 C CG . ASP A 1 668 ? -91.096 -9.775 37.143 1.00 61.22 ? 694 ASP A CG 1 ATOM 5103 O OD1 . ASP A 1 668 ? -91.619 -10.793 37.647 1.00 67.94 ? 694 ASP A OD1 1 ATOM 5104 O OD2 . ASP A 1 668 ? -89.925 -9.727 36.732 1.00 62.83 ? 694 ASP A OD2 1 ATOM 5105 N N . LEU A 1 669 ? -93.823 -10.433 39.177 1.00 63.21 ? 695 LEU A N 1 ATOM 5106 C CA . LEU A 1 669 ? -93.887 -11.094 40.463 1.00 53.02 ? 695 LEU A CA 1 ATOM 5107 C C . LEU A 1 669 ? -93.436 -12.509 40.362 1.00 53.08 ? 695 LEU A C 1 ATOM 5108 O O . LEU A 1 669 ? -93.829 -13.328 41.189 1.00 61.88 ? 695 LEU A O 1 ATOM 5109 C CB . LEU A 1 669 ? -95.300 -11.086 41.003 1.00 54.57 ? 695 LEU A CB 1 ATOM 5110 C CG . LEU A 1 669 ? -95.937 -9.732 41.248 1.00 64.86 ? 695 LEU A CG 1 ATOM 5111 C CD1 . LEU A 1 669 ? -97.378 -9.916 41.655 1.00 72.46 ? 695 LEU A CD1 1 ATOM 5112 C CD2 . LEU A 1 669 ? -95.184 -8.971 42.324 1.00 76.16 ? 695 LEU A CD2 1 ATOM 5113 N N . ARG A 1 670 ? -92.609 -12.847 39.376 1.00 51.82 ? 696 ARG A N 1 ATOM 5114 C CA . ARG A 1 670 ? -92.183 -14.235 39.331 1.00 58.91 ? 696 ARG A CA 1 ATOM 5115 C C . ARG A 1 670 ? -91.423 -14.598 40.617 1.00 62.29 ? 696 ARG A C 1 ATOM 5116 O O . ARG A 1 670 ? -91.010 -13.740 41.379 1.00 64.24 ? 696 ARG A O 1 ATOM 5117 C CB . ARG A 1 670 ? -91.279 -14.595 38.139 1.00 63.05 ? 696 ARG A CB 1 ATOM 5118 C CG . ARG A 1 670 ? -91.825 -14.310 36.756 1.00 67.32 ? 696 ARG A CG 1 ATOM 5119 C CD . ARG A 1 670 ? -91.232 -13.063 36.184 1.00 68.99 ? 696 ARG A CD 1 ATOM 5120 N NE . ARG A 1 670 ? -89.900 -13.404 35.725 1.00 79.16 ? 696 ARG A NE 1 ATOM 5121 C CZ . ARG A 1 670 ? -88.979 -12.528 35.385 1.00 81.71 ? 696 ARG A CZ 1 ATOM 5122 N NH1 . ARG A 1 670 ? -89.153 -11.247 35.640 1.00 81.34 ? 696 ARG A NH1 1 ATOM 5123 N NH2 . ARG A 1 670 ? -87.813 -12.961 34.967 1.00 89.70 ? 696 ARG A NH2 1 ATOM 5124 N N . GLY A 1 671 ? -91.257 -15.890 40.834 1.00 67.76 ? 697 GLY A N 1 ATOM 5125 C CA . GLY A 1 671 ? -90.523 -16.408 41.965 1.00 66.83 ? 697 GLY A CA 1 ATOM 5126 C C . GLY A 1 671 ? -90.921 -16.003 43.371 1.00 73.17 ? 697 GLY A C 1 ATOM 5127 O O . GLY A 1 671 ? -90.089 -15.569 44.157 1.00 66.71 ? 697 GLY A O 1 ATOM 5128 N N . ASN A 1 672 ? -92.205 -16.011 43.645 1.00 70.41 ? 698 ASN A N 1 ATOM 5129 C CA . ASN A 1 672 ? -92.680 -15.736 44.975 1.00 65.42 ? 698 ASN A CA 1 ATOM 5130 C C . ASN A 1 672 ? -93.442 -16.974 45.465 1.00 61.14 ? 698 ASN A C 1 ATOM 5131 O O . ASN A 1 672 ? -93.209 -18.077 45.000 1.00 67.69 ? 698 ASN A O 1 ATOM 5132 C CB . ASN A 1 672 ? -93.521 -14.453 45.089 1.00 69.19 ? 698 ASN A CB 1 ATOM 5133 C CG . ASN A 1 672 ? -92.676 -13.177 45.073 1.00 75.81 ? 698 ASN A CG 1 ATOM 5134 O OD1 . ASN A 1 672 ? -92.415 -12.587 46.127 1.00 70.73 ? 698 ASN A OD1 1 ATOM 5135 N ND2 . ASN A 1 672 ? -92.153 -12.819 43.920 1.00 76.72 ? 698 ASN A ND2 1 ATOM 5136 N N . LYS A 1 673 ? -94.292 -16.787 46.451 1.00 68.77 ? 699 LYS A N 1 ATOM 5137 C CA . LYS A 1 673 ? -95.087 -17.852 47.030 1.00 76.39 ? 699 LYS A CA 1 ATOM 5138 C C . LYS A 1 673 ? -96.577 -17.477 46.962 1.00 74.24 ? 699 LYS A C 1 ATOM 5139 O O . LYS A 1 673 ? -97.375 -17.906 47.796 1.00 76.96 ? 699 LYS A O 1 ATOM 5140 C CB . LYS A 1 673 ? -94.652 -18.000 48.493 1.00 71.99 ? 699 LYS A CB 1 ATOM 5141 C CG . LYS A 1 673 ? -93.376 -18.790 48.714 1.00 72.87 ? 699 LYS A CG 1 ATOM 5142 C CD . LYS A 1 673 ? -92.839 -18.488 50.111 1.00 80.06 ? 699 LYS A CD 1 ATOM 5143 C CE . LYS A 1 673 ? -91.781 -19.476 50.568 1.00 73.49 ? 699 LYS A CE 1 ATOM 5144 N NZ . LYS A 1 673 ? -91.241 -19.031 51.890 1.00 81.22 ? 699 LYS A NZ 1 ATOM 5145 N N . LEU A 1 674 ? -96.947 -16.673 45.971 1.00 73.24 ? 700 LEU A N 1 ATOM 5146 C CA . LEU A 1 674 ? -98.346 -16.204 45.841 1.00 82.20 ? 700 LEU A CA 1 ATOM 5147 C C . LEU A 1 674 ? -99.403 -17.293 45.788 1.00 83.31 ? 700 LEU A C 1 ATOM 5148 O O . LEU A 1 674 ? -99.293 -18.267 45.021 1.00 59.29 ? 700 LEU A O 1 ATOM 5149 C CB . LEU A 1 674 ? -98.507 -15.292 44.650 1.00 78.61 ? 700 LEU A CB 1 ATOM 5150 C CG . LEU A 1 674 ? -97.731 -13.996 44.743 1.00 79.61 ? 700 LEU A CG 1 ATOM 5151 C CD1 . LEU A 1 674 ? -97.813 -13.294 43.411 1.00 90.06 ? 700 LEU A CD1 1 ATOM 5152 C CD2 . LEU A 1 674 ? -98.259 -13.112 45.855 1.00 81.85 ? 700 LEU A CD2 1 ATOM 5153 N N . LEU A 1 675 ? -100.494 -17.023 46.496 1.00 74.83 ? 701 LEU A N 1 ATOM 5154 C CA . LEU A 1 675 ? -101.591 -17.961 46.630 1.00 88.45 ? 701 LEU A CA 1 ATOM 5155 C C . LEU A 1 675 ? -102.862 -17.654 45.843 1.00 88.96 ? 701 LEU A C 1 ATOM 5156 O O . LEU A 1 675 ? -103.376 -18.526 45.145 1.00 89.12 ? 701 LEU A O 1 ATOM 5157 C CB . LEU A 1 675 ? -101.939 -18.058 48.116 1.00 88.68 ? 701 LEU A CB 1 ATOM 5158 C CG . LEU A 1 675 ? -100.812 -18.599 49.003 1.00 93.18 ? 701 LEU A CG 1 ATOM 5159 C CD1 . LEU A 1 675 ? -101.131 -18.425 50.483 1.00 89.56 ? 701 LEU A CD1 1 ATOM 5160 C CD2 . LEU A 1 675 ? -100.513 -20.056 48.659 1.00 86.02 ? 701 LEU A CD2 1 ATOM 5161 N N . PHE A 1 676 ? -103.346 -16.421 45.937 1.00 81.19 ? 702 PHE A N 1 ATOM 5162 C CA . PHE A 1 676 ? -104.571 -16.056 45.267 1.00 87.26 ? 702 PHE A CA 1 ATOM 5163 C C . PHE A 1 676 ? -104.420 -14.871 44.313 1.00 84.99 ? 702 PHE A C 1 ATOM 5164 O O . PHE A 1 676 ? -103.434 -14.163 44.341 1.00 80.11 ? 702 PHE A O 1 ATOM 5165 C CB . PHE A 1 676 ? -105.626 -15.713 46.328 1.00 93.82 ? 702 PHE A CB 1 ATOM 5166 C CG . PHE A 1 676 ? -105.499 -14.326 46.905 1.00 111.96 ? 702 PHE A CG 1 ATOM 5167 C CD1 . PHE A 1 676 ? -106.373 -13.319 46.499 1.00 133.81 ? 702 PHE A CD1 1 ATOM 5168 C CD2 . PHE A 1 676 ? -104.489 -13.999 47.796 1.00 143.75 ? 702 PHE A CD2 1 ATOM 5169 C CE1 . PHE A 1 676 ? -106.278 -12.035 47.014 1.00 146.70 ? 702 PHE A CE1 1 ATOM 5170 C CE2 . PHE A 1 676 ? -104.375 -12.701 48.295 1.00 155.03 ? 702 PHE A CE2 1 ATOM 5171 C CZ . PHE A 1 676 ? -105.273 -11.723 47.909 1.00 150.11 ? 702 PHE A CZ 1 ATOM 5172 N N . LEU A 1 677 ? -105.413 -14.698 43.446 1.00 90.74 ? 703 LEU A N 1 ATOM 5173 C CA . LEU A 1 677 ? -105.461 -13.591 42.490 1.00 77.29 ? 703 LEU A CA 1 ATOM 5174 C C . LEU A 1 677 ? -106.705 -12.747 42.733 1.00 86.78 ? 703 LEU A C 1 ATOM 5175 O O . LEU A 1 677 ? -107.691 -13.230 43.283 1.00 107.95 ? 703 LEU A O 1 ATOM 5176 C CB . LEU A 1 677 ? -105.452 -14.102 41.062 1.00 71.50 ? 703 LEU A CB 1 ATOM 5177 C CG . LEU A 1 677 ? -104.119 -14.650 40.567 1.00 81.00 ? 703 LEU A CG 1 ATOM 5178 C CD1 . LEU A 1 677 ? -104.238 -15.261 39.180 1.00 80.65 ? 703 LEU A CD1 1 ATOM 5179 C CD2 . LEU A 1 677 ? -103.093 -13.529 40.548 1.00 87.58 ? 703 LEU A CD2 1 ATOM 5180 N N . THR A 1 678 ? -106.648 -11.473 42.356 1.00 92.32 ? 704 THR A N 1 ATOM 5181 C CA . THR A 1 678 ? -107.787 -10.576 42.554 1.00 89.32 ? 704 THR A CA 1 ATOM 5182 C C . THR A 1 678 ? -108.892 -10.976 41.607 1.00 89.88 ? 704 THR A C 1 ATOM 5183 O O . THR A 1 678 ? -108.634 -11.409 40.488 1.00 80.83 ? 704 THR A O 1 ATOM 5184 C CB . THR A 1 678 ? -107.428 -9.091 42.312 1.00 93.66 ? 704 THR A CB 1 ATOM 5185 O OG1 . THR A 1 678 ? -108.539 -8.252 42.657 1.00 82.97 ? 704 THR A OG1 1 ATOM 5186 C CG2 . THR A 1 678 ? -107.029 -8.839 40.863 1.00 95.36 ? 704 THR A CG2 1 ATOM 5187 N N . ASP A 1 679 ? -110.124 -10.864 42.081 1.00 109.12 ? 705 ASP A N 1 ATOM 5188 C CA . ASP A 1 679 ? -111.291 -11.215 41.281 1.00 119.37 ? 705 ASP A CA 1 ATOM 5189 C C . ASP A 1 679 ? -111.681 -10.091 40.323 1.00 105.98 ? 705 ASP A C 1 ATOM 5190 O O . ASP A 1 679 ? -112.185 -10.351 39.232 1.00 112.13 ? 705 ASP A O 1 ATOM 5191 C CB . ASP A 1 679 ? -112.472 -11.612 42.189 1.00 126.09 ? 705 ASP A CB 1 ATOM 5192 C CG . ASP A 1 679 ? -112.791 -10.556 43.257 1.00 139.75 ? 705 ASP A CG 1 ATOM 5193 O OD1 . ASP A 1 679 ? -113.858 -10.672 43.896 1.00 147.96 ? 705 ASP A OD1 1 ATOM 5194 O OD2 . ASP A 1 679 ? -111.983 -9.620 43.464 1.00 134.27 ? 705 ASP A OD2 1 ATOM 5195 N N . SER A 1 680 ? -111.365 -8.856 40.701 1.00 90.66 ? 706 SER A N 1 ATOM 5196 C CA . SER A 1 680 ? -111.691 -7.684 39.893 1.00 97.50 ? 706 SER A CA 1 ATOM 5197 C C . SER A 1 680 ? -110.459 -6.847 39.525 1.00 96.67 ? 706 SER A C 1 ATOM 5198 O O . SER A 1 680 ? -110.361 -5.670 39.883 1.00 85.69 ? 706 SER A O 1 ATOM 5199 C CB . SER A 1 680 ? -112.689 -6.825 40.660 1.00 97.09 ? 706 SER A CB 1 ATOM 5200 O OG . SER A 1 680 ? -112.165 -6.481 41.924 1.00 84.95 ? 706 SER A OG 1 ATOM 5201 N N . LEU A 1 681 ? -109.608 -7.403 38.674 1.00 93.04 ? 707 LEU A N 1 ATOM 5202 C CA . LEU A 1 681 ? -108.381 -6.721 38.281 1.00 97.61 ? 707 LEU A CA 1 ATOM 5203 C C . LEU A 1 681 ? -108.641 -5.347 37.630 1.00 90.44 ? 707 LEU A C 1 ATOM 5204 O O . LEU A 1 681 ? -108.042 -4.352 38.031 1.00 101.40 ? 707 LEU A O 1 ATOM 5205 C CB . LEU A 1 681 ? -107.547 -7.635 37.359 1.00 98.89 ? 707 LEU A CB 1 ATOM 5206 C CG . LEU A 1 681 ? -106.031 -7.375 37.177 1.00 97.73 ? 707 LEU A CG 1 ATOM 5207 C CD1 . LEU A 1 681 ? -105.409 -8.378 36.211 1.00 105.01 ? 707 LEU A CD1 1 ATOM 5208 C CD2 . LEU A 1 681 ? -105.703 -5.979 36.726 1.00 92.86 ? 707 LEU A CD2 1 ATOM 5209 N N . SER A 1 682 ? -109.634 -5.251 36.754 1.00 98.41 ? 708 SER A N 1 ATOM 5210 C CA . SER A 1 682 ? -109.894 -3.970 36.066 1.00 98.18 ? 708 SER A CA 1 ATOM 5211 C C . SER A 1 682 ? -110.428 -2.843 36.915 1.00 94.43 ? 708 SER A C 1 ATOM 5212 O O . SER A 1 682 ? -110.584 -1.732 36.422 1.00 87.00 ? 708 SER A O 1 ATOM 5213 C CB . SER A 1 682 ? -110.808 -4.119 34.868 1.00 101.68 ? 708 SER A CB 1 ATOM 5214 O OG . SER A 1 682 ? -111.006 -2.854 34.271 1.00 111.53 ? 708 SER A OG 1 ATOM 5215 N N . ASP A 1 683 ? -110.792 -3.111 38.155 1.00 96.93 ? 709 ASP A N 1 ATOM 5216 C CA . ASP A 1 683 ? -111.271 -2.020 38.985 1.00 114.16 ? 709 ASP A CA 1 ATOM 5217 C C . ASP A 1 683 ? -110.031 -1.319 39.535 1.00 117.85 ? 709 ASP A C 1 ATOM 5218 O O . ASP A 1 683 ? -110.139 -0.268 40.179 1.00 106.23 ? 709 ASP A O 1 ATOM 5219 C CB . ASP A 1 683 ? -112.176 -2.521 40.127 1.00 116.13 ? 709 ASP A CB 1 ATOM 5220 C CG . ASP A 1 683 ? -113.459 -3.189 39.622 1.00 114.16 ? 709 ASP A CG 1 ATOM 5221 O OD1 . ASP A 1 683 ? -113.809 -3.036 38.431 1.00 108.99 ? 709 ASP A OD1 1 ATOM 5222 O OD2 . ASP A 1 683 ? -114.132 -3.849 40.434 1.00 109.07 ? 709 ASP A OD2 1 ATOM 5223 N N . PHE A 1 684 ? -108.847 -1.844 39.192 1.00 116.65 ? 710 PHE A N 1 ATOM 5224 C CA . PHE A 1 684 ? -107.600 -1.273 39.695 1.00 113.15 ? 710 PHE A CA 1 ATOM 5225 C C . PHE A 1 684 ? -106.615 -0.755 38.644 1.00 109.59 ? 710 PHE A C 1 ATOM 5226 O O . PHE A 1 684 ? -105.965 0.262 38.871 1.00 114.86 ? 710 PHE A O 1 ATOM 5227 C CB . PHE A 1 684 ? -106.877 -2.301 40.567 1.00 103.91 ? 710 PHE A CB 1 ATOM 5228 C CG . PHE A 1 684 ? -107.783 -3.034 41.517 1.00 84.72 ? 710 PHE A CG 1 ATOM 5229 C CD1 . PHE A 1 684 ? -108.485 -2.348 42.492 1.00 81.21 ? 710 PHE A CD1 1 ATOM 5230 C CD2 . PHE A 1 684 ? -107.806 -4.422 41.532 1.00 86.11 ? 710 PHE A CD2 1 ATOM 5231 C CE1 . PHE A 1 684 ? -109.301 -3.020 43.387 1.00 83.64 ? 710 PHE A CE1 1 ATOM 5232 C CE2 . PHE A 1 684 ? -108.592 -5.106 42.442 1.00 84.50 ? 710 PHE A CE2 1 ATOM 5233 C CZ . PHE A 1 684 ? -109.340 -4.404 43.375 1.00 84.34 ? 710 PHE A CZ 1 ATOM 5234 N N . THR A 1 685 ? -106.479 -1.450 37.515 1.00 102.62 ? 711 THR A N 1 ATOM 5235 C CA . THR A 1 685 ? -105.525 -1.021 36.475 1.00 99.67 ? 711 THR A CA 1 ATOM 5236 C C . THR A 1 685 ? -106.142 -0.863 35.097 1.00 100.61 ? 711 THR A C 1 ATOM 5237 O O . THR A 1 685 ? -106.923 -1.692 34.651 1.00 112.32 ? 711 THR A O 1 ATOM 5238 C CB . THR A 1 685 ? -104.344 -2.013 36.348 1.00 88.31 ? 711 THR A CB 1 ATOM 5239 O OG1 . THR A 1 685 ? -103.454 -1.596 35.307 1.00 83.38 ? 711 THR A OG1 1 ATOM 5240 C CG2 . THR A 1 685 ? -104.834 -3.371 36.012 1.00 83.62 ? 711 THR A CG2 1 ATOM 5241 N N . SER A 1 686 ? -105.725 0.181 34.400 1.00 99.96 ? 712 SER A N 1 ATOM 5242 C CA . SER A 1 686 ? -106.216 0.450 33.067 1.00 90.66 ? 712 SER A CA 1 ATOM 5243 C C . SER A 1 686 ? -105.025 0.473 32.103 1.00 99.82 ? 712 SER A C 1 ATOM 5244 O O . SER A 1 686 ? -105.208 0.595 30.893 1.00 96.71 ? 712 SER A O 1 ATOM 5245 C CB . SER A 1 686 ? -106.886 1.816 33.063 1.00 87.68 ? 712 SER A CB 1 ATOM 5246 O OG . SER A 1 686 ? -107.792 1.927 34.150 1.00 89.91 ? 712 SER A OG 1 ATOM 5247 N N . SER A 1 687 ? -103.807 0.322 32.646 1.00 100.35 ? 713 SER A N 1 ATOM 5248 C CA . SER A 1 687 ? -102.560 0.357 31.840 1.00 85.76 ? 713 SER A CA 1 ATOM 5249 C C . SER A 1 687 ? -101.719 -0.924 31.821 1.00 73.22 ? 713 SER A C 1 ATOM 5250 O O . SER A 1 687 ? -100.935 -1.142 30.897 1.00 67.65 ? 713 SER A O 1 ATOM 5251 C CB . SER A 1 687 ? -101.675 1.506 32.322 1.00 85.64 ? 713 SER A CB 1 ATOM 5252 O OG . SER A 1 687 ? -101.371 1.360 33.702 1.00 84.99 ? 713 SER A OG 1 ATOM 5253 N N . LEU A 1 688 ? -101.874 -1.776 32.823 1.00 73.27 ? 714 LEU A N 1 ATOM 5254 C CA . LEU A 1 688 ? -101.091 -2.988 32.869 1.00 70.86 ? 714 LEU A CA 1 ATOM 5255 C C . LEU A 1 688 ? -101.191 -3.747 31.545 1.00 63.21 ? 714 LEU A C 1 ATOM 5256 O O . LEU A 1 688 ? -102.269 -3.989 31.054 1.00 72.18 ? 714 LEU A O 1 ATOM 5257 C CB . LEU A 1 688 ? -101.532 -3.859 34.049 1.00 80.62 ? 714 LEU A CB 1 ATOM 5258 C CG . LEU A 1 688 ? -100.664 -5.100 34.324 1.00 96.67 ? 714 LEU A CG 1 ATOM 5259 C CD1 . LEU A 1 688 ? -99.220 -4.689 34.581 1.00 107.97 ? 714 LEU A CD1 1 ATOM 5260 C CD2 . LEU A 1 688 ? -101.182 -5.901 35.511 1.00 90.03 ? 714 LEU A CD2 1 ATOM 5261 N N . ARG A 1 689 ? -100.044 -4.029 30.939 1.00 71.15 ? 715 ARG A N 1 ATOM 5262 C CA . ARG A 1 689 ? -99.953 -4.765 29.672 1.00 69.71 ? 715 ARG A CA 1 ATOM 5263 C C . ARG A 1 689 ? -99.299 -6.118 29.869 1.00 73.51 ? 715 ARG A C 1 ATOM 5264 O O . ARG A 1 689 ? -99.636 -7.074 29.175 1.00 76.29 ? 715 ARG A O 1 ATOM 5265 C CB . ARG A 1 689 ? -99.087 -4.010 28.640 1.00 80.35 ? 715 ARG A CB 1 ATOM 5266 C CG . ARG A 1 689 ? -99.587 -2.638 28.207 1.00 100.50 ? 715 ARG A CG 1 ATOM 5267 C CD . ARG A 1 689 ? -98.637 -1.960 27.209 1.00 114.57 ? 715 ARG A CD 1 ATOM 5268 N NE . ARG A 1 689 ? -98.416 -2.731 25.974 1.00 128.97 ? 715 ARG A NE 1 ATOM 5269 C CZ . ARG A 1 689 ? -97.402 -3.580 25.765 1.00 122.79 ? 715 ARG A CZ 1 ATOM 5270 N NH1 . ARG A 1 689 ? -97.300 -4.225 24.606 1.00 103.73 ? 715 ARG A NH1 1 ATOM 5271 N NH2 . ARG A 1 689 ? -96.482 -3.785 26.701 1.00 130.32 ? 715 ARG A NH2 1 ATOM 5272 N N . THR A 1 690 ? -98.267 -6.173 30.717 1.00 78.19 ? 716 THR A N 1 ATOM 5273 C CA . THR A 1 690 ? -97.556 -7.431 30.953 1.00 72.54 ? 716 THR A CA 1 ATOM 5274 C C . THR A 1 690 ? -97.607 -7.807 32.415 1.00 69.12 ? 716 THR A C 1 ATOM 5275 O O . THR A 1 690 ? -97.310 -6.984 33.273 1.00 77.20 ? 716 THR A O 1 ATOM 5276 C CB . THR A 1 690 ? -96.082 -7.320 30.557 1.00 69.19 ? 716 THR A CB 1 ATOM 5277 O OG1 . THR A 1 690 ? -95.959 -6.731 29.262 1.00 67.51 ? 716 THR A OG1 1 ATOM 5278 C CG2 . THR A 1 690 ? -95.419 -8.697 30.580 1.00 73.34 ? 716 THR A CG2 1 ATOM 5279 N N . LEU A 1 691 ? -97.937 -9.063 32.692 1.00 62.92 ? 717 LEU A N 1 ATOM 5280 C CA . LEU A 1 691 ? -98.029 -9.549 34.069 1.00 67.37 ? 717 LEU A CA 1 ATOM 5281 C C . LEU A 1 691 ? -97.333 -10.908 34.171 1.00 71.65 ? 717 LEU A C 1 ATOM 5282 O O . LEU A 1 691 ? -97.782 -11.910 33.571 1.00 59.98 ? 717 LEU A O 1 ATOM 5283 C CB . LEU A 1 691 ? -99.485 -9.622 34.506 1.00 73.84 ? 717 LEU A CB 1 ATOM 5284 C CG . LEU A 1 691 ? -99.790 -10.067 35.939 1.00 86.63 ? 717 LEU A CG 1 ATOM 5285 C CD1 . LEU A 1 691 ? -99.053 -9.216 36.967 1.00 86.39 ? 717 LEU A CD1 1 ATOM 5286 C CD2 . LEU A 1 691 ? -101.299 -10.017 36.181 1.00 79.30 ? 717 LEU A CD2 1 ATOM 5287 N N . LEU A 1 692 ? -96.219 -10.932 34.915 1.00 66.01 ? 718 LEU A N 1 ATOM 5288 C CA . LEU A 1 692 ? -95.431 -12.147 35.065 1.00 63.17 ? 718 LEU A CA 1 ATOM 5289 C C . LEU A 1 692 ? -95.618 -12.772 36.448 1.00 65.93 ? 718 LEU A C 1 ATOM 5290 O O . LEU A 1 692 ? -95.196 -12.217 37.453 1.00 58.63 ? 718 LEU A O 1 ATOM 5291 C CB . LEU A 1 692 ? -93.979 -11.810 34.825 1.00 72.96 ? 718 LEU A CB 1 ATOM 5292 C CG . LEU A 1 692 ? -93.672 -11.024 33.539 1.00 77.36 ? 718 LEU A CG 1 ATOM 5293 C CD1 . LEU A 1 692 ? -92.175 -10.763 33.462 1.00 64.51 ? 718 LEU A CD1 1 ATOM 5294 C CD2 . LEU A 1 692 ? -94.146 -11.759 32.283 1.00 76.09 ? 718 LEU A CD2 1 ATOM 5295 N N . LEU A 1 693 ? -96.236 -13.949 36.483 1.00 69.34 ? 719 LEU A N 1 ATOM 5296 C CA . LEU A 1 693 ? -96.521 -14.635 37.737 1.00 59.65 ? 719 LEU A CA 1 ATOM 5297 C C . LEU A 1 693 ? -95.972 -16.040 37.746 1.00 55.86 ? 719 LEU A C 1 ATOM 5298 O O . LEU A 1 693 ? -96.449 -16.879 38.514 1.00 57.93 ? 719 LEU A O 1 ATOM 5299 C CB . LEU A 1 693 ? -98.045 -14.715 37.948 1.00 63.77 ? 719 LEU A CB 1 ATOM 5300 C CG . LEU A 1 693 ? -98.835 -13.407 37.951 1.00 72.95 ? 719 LEU A CG 1 ATOM 5301 C CD1 . LEU A 1 693 ? -100.329 -13.652 37.966 1.00 73.80 ? 719 LEU A CD1 1 ATOM 5302 C CD2 . LEU A 1 693 ? -98.440 -12.551 39.138 1.00 85.59 ? 719 LEU A CD2 1 ATOM 5303 N N . SER A 1 694 ? -95.059 -16.366 36.843 1.00 49.12 ? 720 SER A N 1 ATOM 5304 C CA . SER A 1 694 ? -94.512 -17.718 36.884 1.00 56.79 ? 720 SER A CA 1 ATOM 5305 C C . SER A 1 694 ? -93.834 -17.982 38.242 1.00 55.29 ? 720 SER A C 1 ATOM 5306 O O . SER A 1 694 ? -93.431 -17.058 38.936 1.00 67.87 ? 720 SER A O 1 ATOM 5307 C CB . SER A 1 694 ? -93.580 -17.985 35.707 1.00 60.27 ? 720 SER A CB 1 ATOM 5308 O OG . SER A 1 694 ? -92.624 -16.963 35.569 1.00 69.37 ? 720 SER A OG 1 ATOM 5309 N N . HIS A 1 695 ? -93.750 -19.246 38.617 1.00 62.54 ? 721 HIS A N 1 ATOM 5310 C CA . HIS A 1 695 ? -93.161 -19.670 39.894 1.00 63.48 ? 721 HIS A CA 1 ATOM 5311 C C . HIS A 1 695 ? -93.843 -19.093 41.119 1.00 72.03 ? 721 HIS A C 1 ATOM 5312 O O . HIS A 1 695 ? -93.246 -18.417 41.964 1.00 68.84 ? 721 HIS A O 1 ATOM 5313 C CB . HIS A 1 695 ? -91.676 -19.486 39.923 1.00 57.99 ? 721 HIS A CB 1 ATOM 5314 C CG . HIS A 1 695 ? -90.970 -20.366 38.958 1.00 57.49 ? 721 HIS A CG 1 ATOM 5315 N ND1 . HIS A 1 695 ? -90.603 -21.655 39.270 1.00 57.66 ? 721 HIS A ND1 1 ATOM 5316 C CD2 . HIS A 1 695 ? -90.565 -20.152 37.687 1.00 56.30 ? 721 HIS A CD2 1 ATOM 5317 C CE1 . HIS A 1 695 ? -89.977 -22.195 38.237 1.00 55.70 ? 721 HIS A CE1 1 ATOM 5318 N NE2 . HIS A 1 695 ? -89.958 -21.310 37.257 1.00 56.41 ? 721 HIS A NE2 1 ATOM 5319 N N . ASN A 1 696 ? -95.129 -19.371 41.181 1.00 71.48 ? 722 ASN A N 1 ATOM 5320 C CA . ASN A 1 696 ? -95.944 -18.966 42.274 1.00 68.82 ? 722 ASN A CA 1 ATOM 5321 C C . ASN A 1 696 ? -96.774 -20.155 42.726 1.00 64.70 ? 722 ASN A C 1 ATOM 5322 O O . ASN A 1 696 ? -96.403 -21.291 42.410 1.00 61.97 ? 722 ASN A O 1 ATOM 5323 C CB . ASN A 1 696 ? -96.706 -17.710 41.925 1.00 75.55 ? 722 ASN A CB 1 ATOM 5324 C CG . ASN A 1 696 ? -95.854 -16.466 42.110 1.00 74.85 ? 722 ASN A CG 1 ATOM 5325 O OD1 . ASN A 1 696 ? -95.613 -16.062 43.240 1.00 68.64 ? 722 ASN A OD1 1 ATOM 5326 N ND2 . ASN A 1 696 ? -95.573 -15.760 41.028 1.00 80.51 ? 722 ASN A ND2 1 ATOM 5327 N N . ARG A 1 697 ? -97.744 -19.927 43.610 1.00 67.15 ? 723 ARG A N 1 ATOM 5328 C CA . ARG A 1 697 ? -98.589 -21.000 44.133 1.00 72.24 ? 723 ARG A CA 1 ATOM 5329 C C . ARG A 1 697 ? -100.067 -20.736 43.840 1.00 79.64 ? 723 ARG A C 1 ATOM 5330 O O . ARG A 1 697 ? -100.943 -20.905 44.698 1.00 83.81 ? 723 ARG A O 1 ATOM 5331 C CB . ARG A 1 697 ? -98.345 -21.142 45.632 1.00 75.56 ? 723 ARG A CB 1 ATOM 5332 C CG . ARG A 1 697 ? -96.942 -21.606 45.966 1.00 80.07 ? 723 ARG A CG 1 ATOM 5333 C CD . ARG A 1 697 ? -96.676 -21.580 47.462 1.00 78.05 ? 723 ARG A CD 1 ATOM 5334 N NE . ARG A 1 697 ? -95.307 -21.978 47.759 1.00 73.83 ? 723 ARG A NE 1 ATOM 5335 C CZ . ARG A 1 697 ? -94.766 -21.967 48.974 1.00 78.57 ? 723 ARG A CZ 1 ATOM 5336 N NH1 . ARG A 1 697 ? -95.464 -21.552 50.025 1.00 68.54 ? 723 ARG A NH1 1 ATOM 5337 N NH2 . ARG A 1 697 ? -93.504 -22.344 49.129 1.00 85.60 ? 723 ARG A NH2 1 ATOM 5338 N N . ILE A 1 698 ? -100.328 -20.230 42.645 1.00 79.76 ? 724 ILE A N 1 ATOM 5339 C CA . ILE A 1 698 ? -101.681 -19.957 42.234 1.00 76.51 ? 724 ILE A CA 1 ATOM 5340 C C . ILE A 1 698 ? -102.280 -21.306 41.842 1.00 85.25 ? 724 ILE A C 1 ATOM 5341 O O . ILE A 1 698 ? -101.647 -22.102 41.107 1.00 66.48 ? 724 ILE A O 1 ATOM 5342 C CB . ILE A 1 698 ? -101.702 -18.951 41.093 1.00 76.72 ? 724 ILE A CB 1 ATOM 5343 C CG1 . ILE A 1 698 ? -101.239 -17.598 41.634 1.00 75.21 ? 724 ILE A CG1 1 ATOM 5344 C CG2 . ILE A 1 698 ? -103.100 -18.829 40.530 1.00 74.04 ? 724 ILE A CG2 1 ATOM 5345 C CD1 . ILE A 1 698 ? -101.123 -16.491 40.601 1.00 77.86 ? 724 ILE A CD1 1 ATOM 5346 N N . SER A 1 699 ? -103.433 -21.621 42.435 1.00 74.61 ? 725 SER A N 1 ATOM 5347 C CA . SER A 1 699 ? -104.075 -22.901 42.164 1.00 82.01 ? 725 SER A CA 1 ATOM 5348 C C . SER A 1 699 ? -105.409 -22.739 41.491 1.00 80.91 ? 725 SER A C 1 ATOM 5349 O O . SER A 1 699 ? -105.927 -23.680 40.896 1.00 88.50 ? 725 SER A O 1 ATOM 5350 C CB . SER A 1 699 ? -104.235 -23.694 43.458 1.00 74.14 ? 725 SER A CB 1 ATOM 5351 O OG . SER A 1 699 ? -105.008 -22.969 44.405 1.00 77.73 ? 725 SER A OG 1 ATOM 5352 N N . HIS A 1 700 ? -105.920 -21.521 41.511 1.00 79.92 ? 726 HIS A N 1 ATOM 5353 C CA . HIS A 1 700 ? -107.197 -21.233 40.922 1.00 85.45 ? 726 HIS A CA 1 ATOM 5354 C C . HIS A 1 700 ? -107.190 -19.899 40.214 1.00 83.62 ? 726 HIS A C 1 ATOM 5355 O O . HIS A 1 700 ? -106.844 -18.869 40.802 1.00 71.97 ? 726 HIS A O 1 ATOM 5356 C CB . HIS A 1 700 ? -108.266 -21.238 42.022 1.00 92.34 ? 726 HIS A CB 1 ATOM 5357 C CG . HIS A 1 700 ? -109.619 -20.802 41.558 1.00 110.26 ? 726 HIS A CG 1 ATOM 5358 N ND1 . HIS A 1 700 ? -110.499 -21.651 40.918 1.00 120.22 ? 726 HIS A ND1 1 ATOM 5359 C CD2 . HIS A 1 700 ? -110.272 -19.623 41.701 1.00 121.60 ? 726 HIS A CD2 1 ATOM 5360 C CE1 . HIS A 1 700 ? -111.618 -21.000 40.650 1.00 132.10 ? 726 HIS A CE1 1 ATOM 5361 N NE2 . HIS A 1 700 ? -111.507 -19.768 41.117 1.00 124.83 ? 726 HIS A NE2 1 ATOM 5362 N N . LEU A 1 701 ? -107.595 -19.911 38.952 1.00 91.15 ? 727 LEU A N 1 ATOM 5363 C CA . LEU A 1 701 ? -107.659 -18.680 38.179 1.00 95.10 ? 727 LEU A CA 1 ATOM 5364 C C . LEU A 1 701 ? -109.131 -18.299 38.272 1.00 84.68 ? 727 LEU A C 1 ATOM 5365 O O . LEU A 1 701 ? -109.981 -19.103 37.933 1.00 95.72 ? 727 LEU A O 1 ATOM 5366 C CB . LEU A 1 701 ? -107.241 -18.939 36.738 1.00 84.90 ? 727 LEU A CB 1 ATOM 5367 C CG . LEU A 1 701 ? -106.784 -17.708 35.958 1.00 99.22 ? 727 LEU A CG 1 ATOM 5368 C CD1 . LEU A 1 701 ? -106.309 -18.160 34.588 1.00 87.39 ? 727 LEU A CD1 1 ATOM 5369 C CD2 . LEU A 1 701 ? -107.832 -16.601 35.849 1.00 110.07 ? 727 LEU A CD2 1 ATOM 5370 N N . PRO A 1 702 ? -109.444 -17.107 38.804 1.00 99.48 ? 728 PRO A N 1 ATOM 5371 C CA . PRO A 1 702 ? -110.856 -16.733 38.933 1.00 114.29 ? 728 PRO A CA 1 ATOM 5372 C C . PRO A 1 702 ? -111.522 -16.195 37.670 1.00 126.41 ? 728 PRO A C 1 ATOM 5373 O O . PRO A 1 702 ? -110.875 -16.024 36.633 1.00 128.11 ? 728 PRO A O 1 ATOM 5374 C CB . PRO A 1 702 ? -110.839 -15.649 40.020 1.00 111.33 ? 728 PRO A CB 1 ATOM 5375 C CG . PRO A 1 702 ? -109.483 -15.048 39.944 1.00 106.82 ? 728 PRO A CG 1 ATOM 5376 C CD . PRO A 1 702 ? -108.546 -16.084 39.371 1.00 108.40 ? 728 PRO A CD 1 ATOM 5377 N N . SER A 1 703 ? -112.826 -15.948 37.783 1.00 141.55 ? 729 SER A N 1 ATOM 5378 C CA . SER A 1 703 ? -113.627 -15.423 36.688 1.00 132.79 ? 729 SER A CA 1 ATOM 5379 C C . SER A 1 703 ? -112.900 -14.198 36.134 1.00 128.60 ? 729 SER A C 1 ATOM 5380 O O . SER A 1 703 ? -112.375 -13.377 36.889 1.00 142.02 ? 729 SER A O 1 ATOM 5381 C CB . SER A 1 703 ? -115.016 -15.055 37.208 1.00 128.07 ? 729 SER A CB 1 ATOM 5382 O OG . SER A 1 703 ? -115.615 -16.173 37.854 1.00 111.05 ? 729 SER A OG 1 ATOM 5383 N N . GLY A 1 704 ? -112.850 -14.087 34.819 1.00 114.00 ? 730 GLY A N 1 ATOM 5384 C CA . GLY A 1 704 ? -112.145 -12.985 34.188 1.00 120.97 ? 730 GLY A CA 1 ATOM 5385 C C . GLY A 1 704 ? -110.839 -13.536 33.621 1.00 137.55 ? 730 GLY A C 1 ATOM 5386 O O . GLY A 1 704 ? -110.641 -14.749 33.597 1.00 134.41 ? 730 GLY A O 1 ATOM 5387 N N . PHE A 1 705 ? -109.904 -12.665 33.249 1.00 148.00 ? 731 PHE A N 1 ATOM 5388 C CA . PHE A 1 705 ? -110.064 -11.228 33.378 1.00 151.71 ? 731 PHE A CA 1 ATOM 5389 C C . PHE A 1 705 ? -110.155 -10.651 31.956 1.00 138.07 ? 731 PHE A C 1 ATOM 5390 O O . PHE A 1 705 ? -109.339 -11.006 31.119 1.00 128.53 ? 731 PHE A O 1 ATOM 5391 C CB . PHE A 1 705 ? -108.827 -10.658 34.093 1.00 161.48 ? 731 PHE A CB 1 ATOM 5392 C CG . PHE A 1 705 ? -108.310 -11.533 35.215 1.00 180.36 ? 731 PHE A CG 1 ATOM 5393 C CD1 . PHE A 1 705 ? -107.032 -12.097 35.135 1.00 173.84 ? 731 PHE A CD1 1 ATOM 5394 C CD2 . PHE A 1 705 ? -109.150 -11.956 36.233 1.00 167.07 ? 731 PHE A CD2 1 ATOM 5395 C CE1 . PHE A 1 705 ? -106.553 -12.930 36.132 1.00 137.48 ? 731 PHE A CE1 1 ATOM 5396 C CE2 . PHE A 1 705 ? -108.683 -12.809 37.218 1.00 152.40 ? 731 PHE A CE2 1 ATOM 5397 C CZ . PHE A 1 705 ? -107.384 -13.296 37.167 1.00 138.33 ? 731 PHE A CZ 1 ATOM 5398 N N . LEU A 1 706 ? -111.157 -9.828 31.635 1.00 131.61 ? 732 LEU A N 1 ATOM 5399 C CA . LEU A 1 706 ? -112.231 -9.403 32.537 1.00 137.00 ? 732 LEU A CA 1 ATOM 5400 C C . LEU A 1 706 ? -113.532 -9.259 31.762 1.00 133.91 ? 732 LEU A C 1 ATOM 5401 O O . LEU A 1 706 ? -114.284 -10.214 31.613 1.00 126.62 ? 732 LEU A O 1 ATOM 5402 C CB . LEU A 1 706 ? -111.884 -8.060 33.154 1.00 138.58 ? 732 LEU A CB 1 ATOM 5403 C CG . LEU A 1 706 ? -110.704 -8.078 34.113 1.00 142.93 ? 732 LEU A CG 1 ATOM 5404 C CD1 . LEU A 1 706 ? -110.227 -6.682 34.337 1.00 141.78 ? 732 LEU A CD1 1 ATOM 5405 C CD2 . LEU A 1 706 ? -111.050 -8.761 35.432 1.00 132.83 ? 732 LEU A CD2 1 ATOM 5406 N N . SER A 1 710 ? -109.487 -4.465 29.371 1.00 113.90 ? 736 SER A N 1 ATOM 5407 C CA . SER A 1 710 ? -108.136 -4.969 29.582 1.00 109.14 ? 736 SER A CA 1 ATOM 5408 C C . SER A 1 710 ? -107.125 -4.594 28.488 1.00 113.40 ? 736 SER A C 1 ATOM 5409 O O . SER A 1 710 ? -107.335 -4.800 27.273 1.00 83.39 ? 736 SER A O 1 ATOM 5410 C CB . SER A 1 710 ? -108.131 -6.492 29.805 1.00 105.00 ? 736 SER A CB 1 ATOM 5411 O OG . SER A 1 710 ? -108.746 -6.840 31.041 1.00 111.44 ? 736 SER A OG 1 ATOM 5412 N N . SER A 1 711 ? -106.030 -4.015 28.969 1.00 110.87 ? 737 SER A N 1 ATOM 5413 C CA . SER A 1 711 ? -104.893 -3.592 28.164 1.00 98.64 ? 737 SER A CA 1 ATOM 5414 C C . SER A 1 711 ? -103.832 -4.683 28.260 1.00 89.56 ? 737 SER A C 1 ATOM 5415 O O . SER A 1 711 ? -102.803 -4.652 27.590 1.00 84.07 ? 737 SER A O 1 ATOM 5416 C CB . SER A 1 711 ? -104.350 -2.282 28.752 1.00 101.71 ? 737 SER A CB 1 ATOM 5417 O OG . SER A 1 711 ? -104.241 -2.372 30.170 1.00 89.21 ? 737 SER A OG 1 ATOM 5418 N N . LEU A 1 712 ? -104.207 -5.739 28.957 1.00 81.07 ? 738 LEU A N 1 ATOM 5419 C CA . LEU A 1 712 ? -103.337 -6.841 29.242 1.00 82.79 ? 738 LEU A CA 1 ATOM 5420 C C . LEU A 1 712 ? -103.022 -7.708 28.026 1.00 71.79 ? 738 LEU A C 1 ATOM 5421 O O . LEU A 1 712 ? -103.802 -8.555 27.633 1.00 88.02 ? 738 LEU A O 1 ATOM 5422 C CB . LEU A 1 712 ? -103.997 -7.618 30.376 1.00 88.13 ? 738 LEU A CB 1 ATOM 5423 C CG . LEU A 1 712 ? -103.138 -8.354 31.393 1.00 101.30 ? 738 LEU A CG 1 ATOM 5424 C CD1 . LEU A 1 712 ? -103.960 -8.487 32.671 1.00 99.54 ? 738 LEU A CD1 1 ATOM 5425 C CD2 . LEU A 1 712 ? -102.516 -9.668 30.930 1.00 110.48 ? 738 LEU A CD2 1 ATOM 5426 N N . LYS A 1 713 ? -101.821 -7.532 27.491 1.00 76.91 ? 739 LYS A N 1 ATOM 5427 C CA . LYS A 1 713 ? -101.374 -8.279 26.335 1.00 77.10 ? 739 LYS A CA 1 ATOM 5428 C C . LYS A 1 713 ? -100.543 -9.505 26.657 1.00 78.91 ? 739 LYS A C 1 ATOM 5429 O O . LYS A 1 713 ? -100.455 -10.411 25.840 1.00 73.58 ? 739 LYS A O 1 ATOM 5430 C CB . LYS A 1 713 ? -100.565 -7.378 25.403 1.00 87.60 ? 739 LYS A CB 1 ATOM 5431 C CG . LYS A 1 713 ? -101.360 -6.209 24.824 1.00 114.66 ? 739 LYS A CG 1 ATOM 5432 C CD . LYS A 1 713 ? -100.549 -5.463 23.765 1.00 130.37 ? 739 LYS A CD 1 ATOM 5433 C CE . LYS A 1 713 ? -101.372 -4.410 23.025 1.00 130.18 ? 739 LYS A CE 1 ATOM 5434 N NZ . LYS A 1 713 ? -100.626 -3.824 21.870 1.00 126.61 ? 739 LYS A NZ 1 ATOM 5435 N N . HIS A 1 714 ? -99.897 -9.537 27.819 1.00 80.71 ? 740 HIS A N 1 ATOM 5436 C CA . HIS A 1 714 ? -99.056 -10.689 28.166 1.00 79.23 ? 740 HIS A CA 1 ATOM 5437 C C . HIS A 1 714 ? -99.353 -11.171 29.585 1.00 75.75 ? 740 HIS A C 1 ATOM 5438 O O . HIS A 1 714 ? -99.344 -10.382 30.523 1.00 86.12 ? 740 HIS A O 1 ATOM 5439 C CB . HIS A 1 714 ? -97.599 -10.279 28.094 1.00 78.58 ? 740 HIS A CB 1 ATOM 5440 C CG . HIS A 1 714 ? -96.640 -11.411 28.268 1.00 73.43 ? 740 HIS A CG 1 ATOM 5441 N ND1 . HIS A 1 714 ? -95.579 -11.612 27.418 1.00 84.06 ? 740 HIS A ND1 1 ATOM 5442 C CD2 . HIS A 1 714 ? -96.697 -12.512 29.053 1.00 82.73 ? 740 HIS A CD2 1 ATOM 5443 C CE1 . HIS A 1 714 ? -94.918 -12.693 27.790 1.00 78.55 ? 740 HIS A CE1 1 ATOM 5444 N NE2 . HIS A 1 714 ? -95.590 -13.274 28.763 1.00 79.53 ? 740 HIS A NE2 1 ATOM 5445 N N . LEU A 1 715 ? -99.553 -12.475 29.741 1.00 70.03 ? 741 LEU A N 1 ATOM 5446 C CA . LEU A 1 715 ? -99.858 -13.068 31.050 1.00 74.02 ? 741 LEU A CA 1 ATOM 5447 C C . LEU A 1 715 ? -99.084 -14.353 31.216 1.00 83.70 ? 741 LEU A C 1 ATOM 5448 O O . LEU A 1 715 ? -99.274 -15.302 30.441 1.00 76.83 ? 741 LEU A O 1 ATOM 5449 C CB . LEU A 1 715 ? -101.340 -13.387 31.179 1.00 73.64 ? 741 LEU A CB 1 ATOM 5450 C CG . LEU A 1 715 ? -101.727 -14.117 32.469 1.00 76.70 ? 741 LEU A CG 1 ATOM 5451 C CD1 . LEU A 1 715 ? -101.478 -13.232 33.679 1.00 81.06 ? 741 LEU A CD1 1 ATOM 5452 C CD2 . LEU A 1 715 ? -103.184 -14.542 32.443 1.00 72.80 ? 741 LEU A CD2 1 ATOM 5453 N N . ASP A 1 716 ? -98.246 -14.408 32.253 1.00 80.11 ? 742 ASP A N 1 ATOM 5454 C CA . ASP A 1 716 ? -97.438 -15.593 32.492 1.00 74.06 ? 742 ASP A CA 1 ATOM 5455 C C . ASP A 1 716 ? -97.850 -16.301 33.761 1.00 71.01 ? 742 ASP A C 1 ATOM 5456 O O . ASP A 1 716 ? -97.646 -15.783 34.853 1.00 69.84 ? 742 ASP A O 1 ATOM 5457 C CB . ASP A 1 716 ? -95.973 -15.220 32.569 1.00 79.87 ? 742 ASP A CB 1 ATOM 5458 C CG . ASP A 1 716 ? -95.112 -16.395 32.875 1.00 81.95 ? 742 ASP A CG 1 ATOM 5459 O OD1 . ASP A 1 716 ? -95.676 -17.504 32.951 1.00 85.21 ? 742 ASP A OD1 1 ATOM 5460 O OD2 . ASP A 1 716 ? -93.882 -16.219 33.038 1.00 80.14 ? 742 ASP A OD2 1 ATOM 5461 N N . LEU A 1 717 ? -98.431 -17.491 33.598 1.00 73.85 ? 743 LEU A N 1 ATOM 5462 C CA . LEU A 1 717 ? -98.904 -18.313 34.715 1.00 72.87 ? 743 LEU A CA 1 ATOM 5463 C C . LEU A 1 717 ? -98.228 -19.655 34.701 1.00 70.45 ? 743 LEU A C 1 ATOM 5464 O O . LEU A 1 717 ? -98.734 -20.635 35.256 1.00 74.86 ? 743 LEU A O 1 ATOM 5465 C CB . LEU A 1 717 ? -100.420 -18.495 34.655 1.00 72.73 ? 743 LEU A CB 1 ATOM 5466 C CG . LEU A 1 717 ? -101.269 -17.241 34.887 1.00 81.47 ? 743 LEU A CG 1 ATOM 5467 C CD1 . LEU A 1 717 ? -102.715 -17.459 34.473 1.00 89.71 ? 743 LEU A CD1 1 ATOM 5468 C CD2 . LEU A 1 717 ? -101.184 -16.779 36.333 1.00 78.56 ? 743 LEU A CD2 1 ATOM 5469 N N . SER A 1 718 ? -97.079 -19.705 34.057 1.00 63.39 ? 744 SER A N 1 ATOM 5470 C CA . SER A 1 718 ? -96.319 -20.934 33.995 1.00 64.76 ? 744 SER A CA 1 ATOM 5471 C C . SER A 1 718 ? -95.770 -21.286 35.384 1.00 64.43 ? 744 SER A C 1 ATOM 5472 O O . SER A 1 718 ? -95.681 -20.451 36.264 1.00 59.76 ? 744 SER A O 1 ATOM 5473 C CB . SER A 1 718 ? -95.196 -20.797 32.966 1.00 68.67 ? 744 SER A CB 1 ATOM 5474 O OG . SER A 1 718 ? -94.421 -19.637 33.218 1.00 73.68 ? 744 SER A OG 1 ATOM 5475 N N . SER A 1 719 ? -95.444 -22.548 35.576 1.00 66.71 ? 745 SER A N 1 ATOM 5476 C CA . SER A 1 719 ? -94.919 -23.029 36.832 1.00 63.47 ? 745 SER A CA 1 ATOM 5477 C C . SER A 1 719 ? -95.674 -22.617 38.104 1.00 73.04 ? 745 SER A C 1 ATOM 5478 O O . SER A 1 719 ? -95.090 -22.088 39.028 1.00 73.74 ? 745 SER A O 1 ATOM 5479 C CB . SER A 1 719 ? -93.435 -22.737 36.927 1.00 72.11 ? 745 SER A CB 1 ATOM 5480 O OG . SER A 1 719 ? -92.733 -23.426 35.885 1.00 69.11 ? 745 SER A OG 1 ATOM 5481 N N . ASN A 1 720 ? -96.998 -22.732 38.085 1.00 66.70 ? 746 ASN A N 1 ATOM 5482 C CA . ASN A 1 720 ? -97.789 -22.480 39.274 1.00 61.77 ? 746 ASN A CA 1 ATOM 5483 C C . ASN A 1 720 ? -98.427 -23.810 39.664 1.00 66.89 ? 746 ASN A C 1 ATOM 5484 O O . ASN A 1 720 ? -97.880 -24.876 39.353 1.00 69.73 ? 746 ASN A O 1 ATOM 5485 C CB . ASN A 1 720 ? -98.860 -21.430 39.113 1.00 65.47 ? 746 ASN A CB 1 ATOM 5486 C CG . ASN A 1 720 ? -98.320 -20.049 39.082 1.00 69.77 ? 746 ASN A CG 1 ATOM 5487 O OD1 . ASN A 1 720 ? -98.619 -19.253 39.977 1.00 70.31 ? 746 ASN A OD1 1 ATOM 5488 N ND2 . ASN A 1 720 ? -97.438 -19.776 38.141 1.00 74.94 ? 746 ASN A ND2 1 ATOM 5489 N N . LEU A 1 721 ? -99.564 -23.749 40.358 1.00 68.59 ? 747 LEU A N 1 ATOM 5490 C CA . LEU A 1 721 ? -100.268 -24.942 40.780 1.00 78.49 ? 747 LEU A CA 1 ATOM 5491 C C . LEU A 1 721 ? -101.701 -25.012 40.219 1.00 89.84 ? 747 LEU A C 1 ATOM 5492 O O . LEU A 1 721 ? -102.671 -25.163 40.965 1.00 92.30 ? 747 LEU A O 1 ATOM 5493 C CB . LEU A 1 721 ? -100.295 -24.984 42.295 1.00 82.48 ? 747 LEU A CB 1 ATOM 5494 C CG . LEU A 1 721 ? -98.934 -25.075 42.995 1.00 78.36 ? 747 LEU A CG 1 ATOM 5495 C CD1 . LEU A 1 721 ? -99.130 -24.918 44.497 1.00 71.32 ? 747 LEU A CD1 1 ATOM 5496 C CD2 . LEU A 1 721 ? -98.198 -26.369 42.657 1.00 66.75 ? 747 LEU A CD2 1 ATOM 5497 N N . LEU A 1 722 ? -101.834 -24.877 38.906 1.00 94.09 ? 748 LEU A N 1 ATOM 5498 C CA . LEU A 1 722 ? -103.150 -24.944 38.270 1.00 86.03 ? 748 LEU A CA 1 ATOM 5499 C C . LEU A 1 722 ? -103.475 -26.358 37.814 1.00 82.31 ? 748 LEU A C 1 ATOM 5500 O O . LEU A 1 722 ? -102.768 -26.939 36.972 1.00 71.07 ? 748 LEU A O 1 ATOM 5501 C CB . LEU A 1 722 ? -103.245 -23.972 37.105 1.00 78.29 ? 748 LEU A CB 1 ATOM 5502 C CG . LEU A 1 722 ? -103.191 -22.500 37.532 1.00 78.77 ? 748 LEU A CG 1 ATOM 5503 C CD1 . LEU A 1 722 ? -103.117 -21.602 36.313 1.00 69.85 ? 748 LEU A CD1 1 ATOM 5504 C CD2 . LEU A 1 722 ? -104.370 -22.098 38.422 1.00 74.41 ? 748 LEU A CD2 1 ATOM 5505 N N . LYS A 1 723 ? -104.498 -26.932 38.454 1.00 88.88 ? 749 LYS A N 1 ATOM 5506 C CA . LYS A 1 723 ? -104.978 -28.288 38.156 1.00 94.45 ? 749 LYS A CA 1 ATOM 5507 C C . LYS A 1 723 ? -105.754 -28.259 36.827 1.00 95.92 ? 749 LYS A C 1 ATOM 5508 O O . LYS A 1 723 ? -105.657 -29.170 36.007 1.00 80.49 ? 749 LYS A O 1 ATOM 5509 C CB . LYS A 1 723 ? -105.841 -28.821 39.321 1.00 86.20 ? 749 LYS A CB 1 ATOM 5510 C CG . LYS A 1 723 ? -105.052 -29.088 40.604 1.00 91.68 ? 749 LYS A CG 1 ATOM 5511 C CD . LYS A 1 723 ? -105.940 -29.416 41.801 1.00 109.54 ? 749 LYS A CD 1 ATOM 5512 C CE . LYS A 1 723 ? -106.645 -30.766 41.708 1.00 126.72 ? 749 LYS A CE 1 ATOM 5513 N NZ . LYS A 1 723 ? -107.623 -30.945 42.830 1.00 132.92 ? 749 LYS A NZ 1 ATOM 5514 N N . THR A 1 724 ? -106.459 -27.166 36.593 1.00 83.97 ? 750 THR A N 1 ATOM 5515 C CA . THR A 1 724 ? -107.206 -27.001 35.378 1.00 104.88 ? 750 THR A CA 1 ATOM 5516 C C . THR A 1 724 ? -107.670 -25.559 35.302 1.00 103.98 ? 750 THR A C 1 ATOM 5517 O O . THR A 1 724 ? -107.664 -24.847 36.307 1.00 83.46 ? 750 THR A O 1 ATOM 5518 C CB . THR A 1 724 ? -108.420 -27.958 35.342 1.00 128.60 ? 750 THR A CB 1 ATOM 5519 O OG1 . THR A 1 724 ? -109.132 -27.793 34.108 1.00 142.64 ? 750 THR A OG1 1 ATOM 5520 C CG2 . THR A 1 724 ? -109.360 -27.708 36.540 1.00 116.46 ? 750 THR A CG2 1 ATOM 5521 N N . ILE A 1 725 ? -108.051 -25.116 34.111 1.00 110.38 ? 751 ILE A N 1 ATOM 5522 C CA . ILE A 1 725 ? -108.522 -23.754 33.963 1.00 106.74 ? 751 ILE A CA 1 ATOM 5523 C C . ILE A 1 725 ? -110.003 -23.706 33.656 1.00 116.84 ? 751 ILE A C 1 ATOM 5524 O O . ILE A 1 725 ? -110.442 -24.143 32.590 1.00 127.33 ? 751 ILE A O 1 ATOM 5525 C CB . ILE A 1 725 ? -107.784 -22.995 32.872 1.00 104.03 ? 751 ILE A CB 1 ATOM 5526 C CG1 . ILE A 1 725 ? -106.280 -23.155 33.069 1.00 111.88 ? 751 ILE A CG1 1 ATOM 5527 C CG2 . ILE A 1 725 ? -108.224 -21.535 32.882 1.00 98.72 ? 751 ILE A CG2 1 ATOM 5528 C CD1 . ILE A 1 725 ? -105.453 -22.261 32.177 1.00 117.40 ? 751 ILE A CD1 1 ATOM 5529 N N . ASN A 1 726 ? -110.755 -23.110 34.566 1.00 122.23 ? 752 ASN A N 1 ATOM 5530 C CA . ASN A 1 726 ? -112.177 -22.911 34.415 1.00 128.49 ? 752 ASN A CA 1 ATOM 5531 C C . ASN A 1 726 ? -112.384 -21.887 33.322 1.00 134.20 ? 752 ASN A C 1 ATOM 5532 O O . ASN A 1 726 ? -111.456 -21.221 32.916 1.00 126.92 ? 752 ASN A O 1 ATOM 5533 C CB . ASN A 1 726 ? -112.787 -22.455 35.735 1.00 138.48 ? 752 ASN A CB 1 ATOM 5534 C CG . ASN A 1 726 ? -112.846 -23.567 36.772 1.00 136.94 ? 752 ASN A CG 1 ATOM 5535 O OD1 . ASN A 1 726 ? -113.477 -23.418 37.819 1.00 127.62 ? 752 ASN A OD1 1 ATOM 5536 N ND2 . ASN A 1 726 ? -112.190 -24.687 36.486 1.00 122.77 ? 752 ASN A ND2 1 ATOM 5537 N N . LYS A 1 727 ? -113.587 -21.804 32.790 1.00 146.84 ? 753 LYS A N 1 ATOM 5538 C CA . LYS A 1 727 ? -113.785 -21.306 31.444 1.00 144.96 ? 753 LYS A CA 1 ATOM 5539 C C . LYS A 1 727 ? -113.291 -19.891 31.157 1.00 148.46 ? 753 LYS A C 1 ATOM 5540 O O . LYS A 1 727 ? -112.540 -19.693 30.206 1.00 130.35 ? 753 LYS A O 1 ATOM 5541 C CB . LYS A 1 727 ? -115.283 -21.339 31.161 1.00 136.80 ? 753 LYS A CB 1 ATOM 5542 C CG . LYS A 1 727 ? -116.146 -20.975 32.363 1.00 136.81 ? 753 LYS A CG 1 ATOM 5543 C CD . LYS A 1 727 ? -116.239 -22.136 33.340 1.00 139.79 ? 753 LYS A CD 1 ATOM 5544 C CE . LYS A 1 727 ? -116.112 -21.676 34.786 1.00 132.43 ? 753 LYS A CE 1 ATOM 5545 N NZ . LYS A 1 727 ? -116.752 -22.617 35.754 1.00 119.42 ? 753 LYS A NZ 1 ATOM 5546 N N . SER A 1 728 ? -113.653 -18.921 31.987 1.00 141.33 ? 754 SER A N 1 ATOM 5547 C CA . SER A 1 728 ? -112.975 -17.633 31.988 1.00 133.47 ? 754 SER A CA 1 ATOM 5548 C C . SER A 1 728 ? -112.739 -17.029 30.607 1.00 141.88 ? 754 SER A C 1 ATOM 5549 O O . SER A 1 728 ? -111.607 -16.711 30.269 1.00 123.14 ? 754 SER A O 1 ATOM 5550 C CB . SER A 1 728 ? -111.687 -17.689 32.789 1.00 124.01 ? 754 SER A CB 1 ATOM 5551 O OG . SER A 1 728 ? -111.926 -17.253 34.111 1.00 125.07 ? 754 SER A OG 1 ATOM 5552 N N . ALA A 1 729 ? -113.782 -16.921 29.797 1.00 152.74 ? 755 ALA A N 1 ATOM 5553 C CA . ALA A 1 729 ? -113.664 -16.354 28.452 1.00 155.43 ? 755 ALA A CA 1 ATOM 5554 C C . ALA A 1 729 ? -113.309 -14.868 28.443 1.00 154.61 ? 755 ALA A C 1 ATOM 5555 O O . ALA A 1 729 ? -113.761 -14.116 29.296 1.00 162.76 ? 755 ALA A O 1 ATOM 5556 C CB . ALA A 1 729 ? -114.952 -16.579 27.681 1.00 138.39 ? 755 ALA A CB 1 ATOM 5557 N N . LEU A 1 730 ? -112.509 -14.443 27.470 1.00 143.36 ? 756 LEU A N 1 ATOM 5558 C CA . LEU A 1 730 ? -112.193 -13.028 27.326 1.00 137.85 ? 756 LEU A CA 1 ATOM 5559 C C . LEU A 1 730 ? -111.924 -12.365 28.682 1.00 133.99 ? 756 LEU A C 1 ATOM 5560 O O . LEU A 1 730 ? -112.816 -11.795 29.304 1.00 126.41 ? 756 LEU A O 1 ATOM 5561 C CB . LEU A 1 730 ? -113.287 -12.307 26.515 1.00 132.30 ? 756 LEU A CB 1 ATOM 5562 C CG . LEU A 1 730 ? -113.346 -10.774 26.563 1.00 132.92 ? 756 LEU A CG 1 ATOM 5563 C CD1 . LEU A 1 730 ? -114.297 -10.219 27.635 1.00 119.38 ? 756 LEU A CD1 1 ATOM 5564 C CD2 . LEU A 1 730 ? -111.939 -10.177 26.623 1.00 120.48 ? 756 LEU A CD2 1 ATOM 5565 N N . LYS A 1 737 ? -108.085 -9.776 23.491 1.00 91.73 ? 763 LYS A N 1 ATOM 5566 C CA . LYS A 1 737 ? -107.034 -8.757 23.397 1.00 109.77 ? 763 LYS A CA 1 ATOM 5567 C C . LYS A 1 737 ? -105.612 -9.111 23.901 1.00 110.58 ? 763 LYS A C 1 ATOM 5568 O O . LYS A 1 737 ? -104.755 -8.211 23.999 1.00 85.02 ? 763 LYS A O 1 ATOM 5569 C CB . LYS A 1 737 ? -107.499 -7.431 24.023 1.00 118.17 ? 763 LYS A CB 1 ATOM 5570 C CG . LYS A 1 737 ? -108.481 -6.657 23.149 1.00 140.97 ? 763 LYS A CG 1 ATOM 5571 C CD . LYS A 1 737 ? -108.860 -5.303 23.750 1.00 144.77 ? 763 LYS A CD 1 ATOM 5572 C CE . LYS A 1 737 ? -109.592 -4.400 22.749 1.00 134.11 ? 763 LYS A CE 1 ATOM 5573 N NZ . LYS A 1 737 ? -110.845 -4.981 22.188 1.00 140.66 ? 763 LYS A NZ 1 ATOM 5574 N N . LEU A 1 738 ? -105.325 -10.393 24.156 1.00 97.37 ? 764 LEU A N 1 ATOM 5575 C CA . LEU A 1 738 ? -103.984 -10.755 24.616 1.00 94.30 ? 764 LEU A CA 1 ATOM 5576 C C . LEU A 1 738 ? -103.198 -11.656 23.645 1.00 87.41 ? 764 LEU A C 1 ATOM 5577 O O . LEU A 1 738 ? -103.667 -12.698 23.222 1.00 97.56 ? 764 LEU A O 1 ATOM 5578 C CB . LEU A 1 738 ? -103.989 -11.295 26.061 1.00 98.73 ? 764 LEU A CB 1 ATOM 5579 C CG . LEU A 1 738 ? -104.648 -12.594 26.533 1.00 83.93 ? 764 LEU A CG 1 ATOM 5580 C CD1 . LEU A 1 738 ? -103.984 -13.835 25.968 1.00 86.00 ? 764 LEU A CD1 1 ATOM 5581 C CD2 . LEU A 1 738 ? -104.588 -12.622 28.051 1.00 79.24 ? 764 LEU A CD2 1 ATOM 5582 N N . SER A 1 739 ? -101.984 -11.217 23.322 1.00 76.81 ? 765 SER A N 1 ATOM 5583 C CA . SER A 1 739 ? -101.075 -11.901 22.404 1.00 78.55 ? 765 SER A CA 1 ATOM 5584 C C . SER A 1 739 ? -100.331 -13.116 22.951 1.00 84.83 ? 765 SER A C 1 ATOM 5585 O O . SER A 1 739 ? -99.718 -13.859 22.165 1.00 80.12 ? 765 SER A O 1 ATOM 5586 C CB . SER A 1 739 ? -99.968 -10.924 21.968 1.00 81.63 ? 765 SER A CB 1 ATOM 5587 O OG . SER A 1 739 ? -100.491 -9.718 21.447 1.00 103.92 ? 765 SER A OG 1 ATOM 5588 N N . MET A 1 740 ? -100.239 -13.249 24.277 1.00 89.23 ? 766 MET A N 1 ATOM 5589 C CA . MET A 1 740 ? -99.491 -14.378 24.849 1.00 90.64 ? 766 MET A CA 1 ATOM 5590 C C . MET A 1 740 ? -99.983 -14.819 26.215 1.00 76.70 ? 766 MET A C 1 ATOM 5591 O O . MET A 1 740 ? -100.487 -14.014 26.995 1.00 72.85 ? 766 MET A O 1 ATOM 5592 C CB . MET A 1 740 ? -97.996 -14.036 24.902 1.00 87.77 ? 766 MET A CB 1 ATOM 5593 C CG . MET A 1 740 ? -97.108 -15.164 25.387 1.00 97.39 ? 766 MET A CG 1 ATOM 5594 S SD . MET A 1 740 ? -95.345 -14.789 25.250 1.00 99.80 ? 766 MET A SD 1 ATOM 5595 C CE . MET A 1 740 ? -95.148 -14.662 23.475 1.00 95.80 ? 766 MET A CE 1 ATOM 5596 N N . LEU A 1 741 ? -99.853 -16.121 26.469 1.00 68.22 ? 767 LEU A N 1 ATOM 5597 C CA . LEU A 1 741 ? -100.276 -16.731 27.724 1.00 70.31 ? 767 LEU A CA 1 ATOM 5598 C C . LEU A 1 741 ? -99.336 -17.883 27.989 1.00 85.68 ? 767 LEU A C 1 ATOM 5599 O O . LEU A 1 741 ? -99.282 -18.834 27.195 1.00 71.29 ? 767 LEU A O 1 ATOM 5600 C CB . LEU A 1 741 ? -101.675 -17.270 27.596 1.00 74.55 ? 767 LEU A CB 1 ATOM 5601 C CG . LEU A 1 741 ? -102.253 -17.951 28.825 1.00 87.40 ? 767 LEU A CG 1 ATOM 5602 C CD1 . LEU A 1 741 ? -102.456 -16.930 29.932 1.00 89.71 ? 767 LEU A CD1 1 ATOM 5603 C CD2 . LEU A 1 741 ? -103.580 -18.600 28.459 1.00 89.09 ? 767 LEU A CD2 1 ATOM 5604 N N . GLU A 1 742 ? -98.596 -17.815 29.096 1.00 76.64 ? 768 GLU A N 1 ATOM 5605 C CA . GLU A 1 742 ? -97.646 -18.866 29.397 1.00 77.44 ? 768 GLU A CA 1 ATOM 5606 C C . GLU A 1 742 ? -98.253 -19.803 30.426 1.00 78.43 ? 768 GLU A C 1 ATOM 5607 O O . GLU A 1 742 ? -98.779 -19.353 31.456 1.00 75.72 ? 768 GLU A O 1 ATOM 5608 C CB . GLU A 1 742 ? -96.346 -18.245 29.876 1.00 93.65 ? 768 GLU A CB 1 ATOM 5609 C CG . GLU A 1 742 ? -95.849 -17.159 28.927 1.00 102.70 ? 768 GLU A CG 1 ATOM 5610 C CD . GLU A 1 742 ? -94.493 -16.593 29.304 1.00 93.58 ? 768 GLU A CD 1 ATOM 5611 O OE1 . GLU A 1 742 ? -93.702 -17.320 29.927 1.00 101.41 ? 768 GLU A OE1 1 ATOM 5612 O OE2 . GLU A 1 742 ? -94.191 -15.451 28.897 1.00 81.13 ? 768 GLU A OE2 1 ATOM 5613 N N . LEU A 1 743 ? -98.178 -21.106 30.150 1.00 71.18 ? 769 LEU A N 1 ATOM 5614 C CA . LEU A 1 743 ? -98.771 -22.114 31.042 1.00 70.14 ? 769 LEU A CA 1 ATOM 5615 C C . LEU A 1 743 ? -97.943 -23.361 31.372 1.00 70.08 ? 769 LEU A C 1 ATOM 5616 O O . LEU A 1 743 ? -98.323 -24.112 32.281 1.00 73.34 ? 769 LEU A O 1 ATOM 5617 C CB . LEU A 1 743 ? -100.121 -22.555 30.468 1.00 70.62 ? 769 LEU A CB 1 ATOM 5618 C CG . LEU A 1 743 ? -101.210 -21.478 30.419 1.00 87.14 ? 769 LEU A CG 1 ATOM 5619 C CD1 . LEU A 1 743 ? -102.403 -21.923 29.603 1.00 97.72 ? 769 LEU A CD1 1 ATOM 5620 C CD2 . LEU A 1 743 ? -101.650 -21.086 31.822 1.00 99.79 ? 769 LEU A CD2 1 ATOM 5621 N N . HIS A 1 744 ? -96.808 -23.581 30.706 1.00 60.39 ? 770 HIS A N 1 ATOM 5622 C CA . HIS A 1 744 ? -96.023 -24.784 31.017 1.00 67.80 ? 770 HIS A CA 1 ATOM 5623 C C . HIS A 1 744 ? -95.717 -24.828 32.500 1.00 67.14 ? 770 HIS A C 1 ATOM 5624 O O . HIS A 1 744 ? -95.667 -23.802 33.168 1.00 78.72 ? 770 HIS A O 1 ATOM 5625 C CB . HIS A 1 744 ? -94.705 -24.811 30.247 1.00 82.07 ? 770 HIS A CB 1 ATOM 5626 C CG . HIS A 1 744 ? -93.711 -23.801 30.722 1.00 96.04 ? 770 HIS A CG 1 ATOM 5627 N ND1 . HIS A 1 744 ? -92.647 -24.138 31.532 1.00 95.38 ? 770 HIS A ND1 1 ATOM 5628 C CD2 . HIS A 1 744 ? -93.678 -22.452 30.596 1.00 93.96 ? 770 HIS A CD2 1 ATOM 5629 C CE1 . HIS A 1 744 ? -91.966 -23.047 31.832 1.00 105.47 ? 770 HIS A CE1 1 ATOM 5630 N NE2 . HIS A 1 744 ? -92.576 -22.010 31.285 1.00 101.11 ? 770 HIS A NE2 1 ATOM 5631 N N . GLY A 1 745 ? -95.551 -26.018 33.031 1.00 73.01 ? 771 GLY A N 1 ATOM 5632 C CA . GLY A 1 745 ? -95.221 -26.151 34.430 1.00 70.74 ? 771 GLY A CA 1 ATOM 5633 C C . GLY A 1 745 ? -96.344 -26.260 35.418 1.00 71.27 ? 771 GLY A C 1 ATOM 5634 O O . GLY A 1 745 ? -96.091 -26.352 36.611 1.00 96.42 ? 771 GLY A O 1 ATOM 5635 N N . ASN A 1 746 ? -97.587 -26.162 34.987 1.00 79.67 ? 772 ASN A N 1 ATOM 5636 C CA . ASN A 1 746 ? -98.645 -26.324 35.965 1.00 79.49 ? 772 ASN A CA 1 ATOM 5637 C C . ASN A 1 746 ? -99.025 -27.782 35.970 1.00 80.70 ? 772 ASN A C 1 ATOM 5638 O O . ASN A 1 746 ? -98.831 -28.471 34.963 1.00 77.54 ? 772 ASN A O 1 ATOM 5639 C CB . ASN A 1 746 ? -99.866 -25.478 35.698 1.00 77.46 ? 772 ASN A CB 1 ATOM 5640 C CG . ASN A 1 746 ? -99.567 -24.011 35.720 1.00 79.59 ? 772 ASN A CG 1 ATOM 5641 O OD1 . ASN A 1 746 ? -100.004 -23.303 36.624 1.00 81.19 ? 772 ASN A OD1 1 ATOM 5642 N ND2 . ASN A 1 746 ? -98.710 -23.567 34.813 1.00 81.96 ? 772 ASN A ND2 1 ATOM 5643 N N . PRO A 1 747 ? -99.513 -28.271 37.118 1.00 79.09 ? 773 PRO A N 1 ATOM 5644 C CA . PRO A 1 747 ? -99.919 -29.644 37.258 1.00 84.93 ? 773 PRO A CA 1 ATOM 5645 C C . PRO A 1 747 ? -101.405 -29.808 36.822 1.00 89.06 ? 773 PRO A C 1 ATOM 5646 O O . PRO A 1 747 ? -102.318 -29.911 37.658 1.00 87.04 ? 773 PRO A O 1 ATOM 5647 C CB . PRO A 1 747 ? -99.725 -29.885 38.758 1.00 70.12 ? 773 PRO A CB 1 ATOM 5648 C CG . PRO A 1 747 ? -100.084 -28.569 39.381 1.00 76.41 ? 773 PRO A CG 1 ATOM 5649 C CD . PRO A 1 747 ? -99.840 -27.500 38.334 1.00 81.81 ? 773 PRO A CD 1 ATOM 5650 N N . PHE A 1 748 ? -101.635 -29.786 35.515 1.00 92.37 ? 774 PHE A N 1 ATOM 5651 C CA . PHE A 1 748 ? -102.988 -29.921 34.970 1.00 92.03 ? 774 PHE A CA 1 ATOM 5652 C C . PHE A 1 748 ? -103.649 -31.281 35.179 1.00 86.71 ? 774 PHE A C 1 ATOM 5653 O O . PHE A 1 748 ? -103.038 -32.324 34.909 1.00 75.04 ? 774 PHE A O 1 ATOM 5654 C CB . PHE A 1 748 ? -102.988 -29.646 33.479 1.00 87.13 ? 774 PHE A CB 1 ATOM 5655 C CG . PHE A 1 748 ? -102.718 -28.232 33.128 1.00 79.42 ? 774 PHE A CG 1 ATOM 5656 C CD1 . PHE A 1 748 ? -103.737 -27.302 33.172 1.00 83.51 ? 774 PHE A CD1 1 ATOM 5657 C CD2 . PHE A 1 748 ? -101.495 -27.855 32.639 1.00 86.16 ? 774 PHE A CD2 1 ATOM 5658 C CE1 . PHE A 1 748 ? -103.516 -25.993 32.805 1.00 88.93 ? 774 PHE A CE1 1 ATOM 5659 C CE2 . PHE A 1 748 ? -101.259 -26.549 32.275 1.00 85.96 ? 774 PHE A CE2 1 ATOM 5660 C CZ . PHE A 1 748 ? -102.272 -25.617 32.355 1.00 92.00 ? 774 PHE A CZ 1 ATOM 5661 N N . GLU A 1 749 ? -104.918 -31.249 35.596 1.00 78.93 ? 775 GLU A N 1 ATOM 5662 C CA . GLU A 1 749 ? -105.722 -32.463 35.826 1.00 102.38 ? 775 GLU A CA 1 ATOM 5663 C C . GLU A 1 749 ? -106.476 -32.793 34.510 1.00 109.80 ? 775 GLU A C 1 ATOM 5664 O O . GLU A 1 749 ? -107.472 -32.132 34.135 1.00 85.13 ? 775 GLU A O 1 ATOM 5665 C CB . GLU A 1 749 ? -106.685 -32.252 37.002 1.00 107.30 ? 775 GLU A CB 1 ATOM 5666 C CG . GLU A 1 749 ? -107.487 -33.485 37.391 1.00 118.81 ? 775 GLU A CG 1 ATOM 5667 C CD . GLU A 1 749 ? -108.282 -33.299 38.677 1.00 127.36 ? 775 GLU A CD 1 ATOM 5668 O OE1 . GLU A 1 749 ? -108.644 -34.319 39.290 1.00 146.57 ? 775 GLU A OE1 1 ATOM 5669 O OE2 . GLU A 1 749 ? -108.464 -32.149 39.131 1.00 121.77 ? 775 GLU A OE2 1 ATOM 5670 N N . CYS A 1 750 ? -105.957 -33.790 33.794 1.00 104.52 ? 776 CYS A N 1 ATOM 5671 C CA . CYS A 1 750 ? -106.521 -34.203 32.511 1.00 113.95 ? 776 CYS A CA 1 ATOM 5672 C C . CYS A 1 750 ? -107.762 -35.109 32.513 1.00 111.00 ? 776 CYS A C 1 ATOM 5673 O O . CYS A 1 750 ? -107.765 -36.194 31.935 1.00 94.98 ? 776 CYS A O 1 ATOM 5674 C CB . CYS A 1 750 ? -105.415 -34.736 31.595 1.00 108.31 ? 776 CYS A CB 1 ATOM 5675 S SG . CYS A 1 750 ? -104.323 -33.390 31.080 1.00 99.87 ? 776 CYS A SG 1 ATOM 5676 N N . THR A 1 751 ? -108.805 -34.647 33.194 1.00 104.20 ? 777 THR A N 1 ATOM 5677 C CA . THR A 1 751 ? -110.064 -35.342 33.232 1.00 103.60 ? 777 THR A CA 1 ATOM 5678 C C . THR A 1 751 ? -110.819 -34.595 32.140 1.00 116.28 ? 777 THR A C 1 ATOM 5679 O O . THR A 1 751 ? -110.255 -33.698 31.508 1.00 116.55 ? 777 THR A O 1 ATOM 5680 C CB . THR A 1 751 ? -110.797 -35.212 34.592 1.00 109.67 ? 777 THR A CB 1 ATOM 5681 O OG1 . THR A 1 751 ? -111.096 -33.839 34.872 1.00 113.79 ? 777 THR A OG1 1 ATOM 5682 C CG2 . THR A 1 751 ? -109.959 -35.781 35.716 1.00 113.23 ? 777 THR A CG2 1 ATOM 5683 N N . CYS A 1 752 ? -112.080 -34.927 31.914 1.00 132.43 ? 778 CYS A N 1 ATOM 5684 C CA . CYS A 1 752 ? -112.839 -34.239 30.874 1.00 137.65 ? 778 CYS A CA 1 ATOM 5685 C C . CYS A 1 752 ? -113.012 -32.733 31.119 1.00 130.42 ? 778 CYS A C 1 ATOM 5686 O O . CYS A 1 752 ? -113.415 -32.000 30.207 1.00 132.11 ? 778 CYS A O 1 ATOM 5687 C CB . CYS A 1 752 ? -114.166 -34.956 30.584 1.00 146.05 ? 778 CYS A CB 1 ATOM 5688 S SG . CYS A 1 752 ? -113.960 -36.512 29.658 1.00 121.43 ? 778 CYS A SG 1 ATOM 5689 N N . ASP A 1 753 ? -112.644 -32.275 32.323 1.00 133.14 ? 779 ASP A N 1 ATOM 5690 C CA . ASP A 1 753 ? -112.719 -30.846 32.698 1.00 121.86 ? 779 ASP A CA 1 ATOM 5691 C C . ASP A 1 753 ? -111.717 -30.022 31.906 1.00 113.47 ? 779 ASP A C 1 ATOM 5692 O O . ASP A 1 753 ? -111.807 -28.800 31.867 1.00 102.13 ? 779 ASP A O 1 ATOM 5693 C CB . ASP A 1 753 ? -112.422 -30.651 34.189 1.00 124.41 ? 779 ASP A CB 1 ATOM 5694 C CG . ASP A 1 753 ? -113.488 -31.240 35.085 1.00 128.76 ? 779 ASP A CG 1 ATOM 5695 O OD1 . ASP A 1 753 ? -114.672 -31.210 34.699 1.00 144.41 ? 779 ASP A OD1 1 ATOM 5696 O OD2 . ASP A 1 753 ? -113.160 -31.623 36.226 1.00 120.28 ? 779 ASP A OD2 1 ATOM 5697 N N . ILE A 1 754 ? -110.756 -30.699 31.282 1.00 111.11 ? 780 ILE A N 1 ATOM 5698 C CA . ILE A 1 754 ? -109.743 -30.028 30.494 1.00 99.53 ? 780 ILE A CA 1 ATOM 5699 C C . ILE A 1 754 ? -110.344 -29.701 29.133 1.00 100.54 ? 780 ILE A C 1 ATOM 5700 O O . ILE A 1 754 ? -109.619 -29.454 28.173 1.00 101.57 ? 780 ILE A O 1 ATOM 5701 C CB . ILE A 1 754 ? -108.522 -30.947 30.277 1.00 106.71 ? 780 ILE A CB 1 ATOM 5702 C CG1 . ILE A 1 754 ? -107.248 -30.129 30.073 1.00 110.91 ? 780 ILE A CG1 1 ATOM 5703 C CG2 . ILE A 1 754 ? -108.791 -31.980 29.189 1.00 106.93 ? 780 ILE A CG2 1 ATOM 5704 C CD1 . ILE A 1 754 ? -106.881 -29.309 31.294 1.00 109.92 ? 780 ILE A CD1 1 ATOM 5705 N N . GLY A 1 755 ? -111.676 -29.702 29.059 1.00 92.22 ? 781 GLY A N 1 ATOM 5706 C CA . GLY A 1 755 ? -112.378 -29.431 27.823 1.00 77.96 ? 781 GLY A CA 1 ATOM 5707 C C . GLY A 1 755 ? -112.630 -27.966 27.557 1.00 87.41 ? 781 GLY A C 1 ATOM 5708 O O . GLY A 1 755 ? -112.385 -27.489 26.439 1.00 92.34 ? 781 GLY A O 1 ATOM 5709 N N . ASP A 1 756 ? -113.161 -27.255 28.557 1.00 94.32 ? 782 ASP A N 1 ATOM 5710 C CA . ASP A 1 756 ? -113.449 -25.814 28.410 1.00 110.68 ? 782 ASP A CA 1 ATOM 5711 C C . ASP A 1 756 ? -112.200 -25.117 27.911 1.00 115.58 ? 782 ASP A C 1 ATOM 5712 O O . ASP A 1 756 ? -112.240 -24.330 26.963 1.00 114.78 ? 782 ASP A O 1 ATOM 5713 C CB . ASP A 1 756 ? -113.834 -25.152 29.745 1.00 120.52 ? 782 ASP A CB 1 ATOM 5714 C CG . ASP A 1 756 ? -115.065 -25.752 30.380 1.00 119.41 ? 782 ASP A CG 1 ATOM 5715 O OD1 . ASP A 1 756 ? -115.381 -26.928 30.117 1.00 130.07 ? 782 ASP A OD1 1 ATOM 5716 O OD2 . ASP A 1 756 ? -115.658 -25.061 31.231 1.00 129.35 ? 782 ASP A OD2 1 ATOM 5717 N N . PHE A 1 757 ? -111.099 -25.363 28.613 1.00 106.22 ? 783 PHE A N 1 ATOM 5718 C CA . PHE A 1 757 ? -109.837 -24.777 28.250 1.00 115.11 ? 783 PHE A CA 1 ATOM 5719 C C . PHE A 1 757 ? -109.388 -25.316 26.897 1.00 109.82 ? 783 PHE A C 1 ATOM 5720 O O . PHE A 1 757 ? -109.134 -24.548 25.971 1.00 123.58 ? 783 PHE A O 1 ATOM 5721 C CB . PHE A 1 757 ? -108.776 -25.013 29.338 1.00 119.74 ? 783 PHE A CB 1 ATOM 5722 C CG . PHE A 1 757 ? -107.404 -24.551 28.940 1.00 113.08 ? 783 PHE A CG 1 ATOM 5723 C CD1 . PHE A 1 757 ? -107.115 -23.190 28.852 1.00 100.93 ? 783 PHE A CD1 1 ATOM 5724 C CD2 . PHE A 1 757 ? -106.399 -25.469 28.666 1.00 98.77 ? 783 PHE A CD2 1 ATOM 5725 C CE1 . PHE A 1 757 ? -105.873 -22.760 28.444 1.00 86.84 ? 783 PHE A CE1 1 ATOM 5726 C CE2 . PHE A 1 757 ? -105.148 -25.037 28.275 1.00 101.53 ? 783 PHE A CE2 1 ATOM 5727 C CZ . PHE A 1 757 ? -104.885 -23.684 28.165 1.00 95.91 ? 783 PHE A CZ 1 ATOM 5728 N N . ARG A 1 758 ? -109.312 -26.634 26.774 1.00 105.84 ? 784 ARG A N 1 ATOM 5729 C CA . ARG A 1 758 ? -108.903 -27.242 25.515 1.00 105.84 ? 784 ARG A CA 1 ATOM 5730 C C . ARG A 1 758 ? -109.650 -26.565 24.372 1.00 109.32 ? 784 ARG A C 1 ATOM 5731 O O . ARG A 1 758 ? -109.107 -26.356 23.271 1.00 94.26 ? 784 ARG A O 1 ATOM 5732 C CB . ARG A 1 758 ? -109.186 -28.727 25.543 1.00 113.33 ? 784 ARG A CB 1 ATOM 5733 C CG . ARG A 1 758 ? -108.884 -29.416 24.242 1.00 123.35 ? 784 ARG A CG 1 ATOM 5734 C CD . ARG A 1 758 ? -107.494 -29.070 23.771 1.00 113.46 ? 784 ARG A CD 1 ATOM 5735 N NE . ARG A 1 758 ? -107.106 -29.989 22.729 1.00 133.16 ? 784 ARG A NE 1 ATOM 5736 C CZ . ARG A 1 758 ? -106.603 -31.187 22.985 1.00 140.14 ? 784 ARG A CZ 1 ATOM 5737 N NH1 . ARG A 1 758 ? -106.266 -32.001 21.995 1.00 143.83 ? 784 ARG A NH1 1 ATOM 5738 N NH2 . ARG A 1 758 ? -106.456 -31.578 24.248 1.00 132.47 ? 784 ARG A NH2 1 ATOM 5739 N N . ARG A 1 759 ? -110.925 -26.293 24.627 1.00 101.62 ? 785 ARG A N 1 ATOM 5740 C CA . ARG A 1 759 ? -111.760 -25.598 23.679 1.00 114.28 ? 785 ARG A CA 1 ATOM 5741 C C . ARG A 1 759 ? -111.107 -24.259 23.366 1.00 118.37 ? 785 ARG A C 1 ATOM 5742 O O . ARG A 1 759 ? -110.683 -23.993 22.235 1.00 115.68 ? 785 ARG A O 1 ATOM 5743 C CB . ARG A 1 759 ? -113.137 -25.324 24.291 1.00 120.59 ? 785 ARG A CB 1 ATOM 5744 C CG . ARG A 1 759 ? -113.863 -24.218 23.554 1.00 131.01 ? 785 ARG A CG 1 ATOM 5745 C CD . ARG A 1 759 ? -115.151 -23.739 24.202 1.00 135.78 ? 785 ARG A CD 1 ATOM 5746 N NE . ARG A 1 759 ? -116.276 -24.644 24.012 1.00 141.33 ? 785 ARG A NE 1 ATOM 5747 C CZ . ARG A 1 759 ? -116.968 -24.730 22.875 1.00 132.37 ? 785 ARG A CZ 1 ATOM 5748 N NH1 . ARG A 1 759 ? -118.021 -25.529 22.802 1.00 117.26 ? 785 ARG A NH1 1 ATOM 5749 N NH2 . ARG A 1 759 ? -116.607 -24.016 21.803 1.00 118.76 ? 785 ARG A NH2 1 ATOM 5750 N N . TRP A 1 760 ? -111.015 -23.441 24.414 1.00 122.26 ? 786 TRP A N 1 ATOM 5751 C CA . TRP A 1 760 ? -110.446 -22.102 24.358 1.00 107.00 ? 786 TRP A CA 1 ATOM 5752 C C . TRP A 1 760 ? -109.307 -21.923 23.387 1.00 105.33 ? 786 TRP A C 1 ATOM 5753 O O . TRP A 1 760 ? -109.296 -20.963 22.616 1.00 93.80 ? 786 TRP A O 1 ATOM 5754 C CB . TRP A 1 760 ? -109.889 -21.724 25.731 1.00 117.38 ? 786 TRP A CB 1 ATOM 5755 C CG . TRP A 1 760 ? -109.307 -20.355 25.753 1.00 120.11 ? 786 TRP A CG 1 ATOM 5756 C CD1 . TRP A 1 760 ? -108.042 -19.973 25.374 1.00 106.22 ? 786 TRP A CD1 1 ATOM 5757 C CD2 . TRP A 1 760 ? -109.967 -19.180 26.186 1.00 125.60 ? 786 TRP A CD2 1 ATOM 5758 N NE1 . TRP A 1 760 ? -107.904 -18.615 25.503 1.00 105.03 ? 786 TRP A NE1 1 ATOM 5759 C CE2 . TRP A 1 760 ? -109.069 -18.105 26.014 1.00 121.67 ? 786 TRP A CE2 1 ATOM 5760 C CE3 . TRP A 1 760 ? -111.234 -18.927 26.707 1.00 122.91 ? 786 TRP A CE3 1 ATOM 5761 C CZ2 . TRP A 1 760 ? -109.401 -16.805 26.351 1.00 135.20 ? 786 TRP A CZ2 1 ATOM 5762 C CZ3 . TRP A 1 760 ? -111.562 -17.654 27.019 1.00 138.89 ? 786 TRP A CZ3 1 ATOM 5763 C CH2 . TRP A 1 760 ? -110.647 -16.597 26.855 1.00 149.26 ? 786 TRP A CH2 1 ATOM 5764 N N . MET A 1 761 ? -108.336 -22.835 23.451 1.00 104.84 ? 787 MET A N 1 ATOM 5765 C CA . MET A 1 761 ? -107.133 -22.742 22.622 1.00 115.86 ? 787 MET A CA 1 ATOM 5766 C C . MET A 1 761 ? -107.485 -22.943 21.168 1.00 122.02 ? 787 MET A C 1 ATOM 5767 O O . MET A 1 761 ? -107.033 -22.198 20.301 1.00 131.09 ? 787 MET A O 1 ATOM 5768 C CB . MET A 1 761 ? -106.120 -23.832 22.973 1.00 116.82 ? 787 MET A CB 1 ATOM 5769 C CG . MET A 1 761 ? -106.207 -24.401 24.378 1.00 120.05 ? 787 MET A CG 1 ATOM 5770 S SD . MET A 1 761 ? -104.691 -25.241 24.866 1.00 119.55 ? 787 MET A SD 1 ATOM 5771 C CE . MET A 1 761 ? -104.122 -25.909 23.301 1.00 117.28 ? 787 MET A CE 1 ATOM 5772 N N . ASP A 1 762 ? -108.257 -23.997 20.915 1.00 131.65 ? 788 ASP A N 1 ATOM 5773 C CA . ASP A 1 762 ? -108.681 -24.355 19.570 1.00 131.54 ? 788 ASP A CA 1 ATOM 5774 C C . ASP A 1 762 ? -109.257 -23.109 18.890 1.00 122.60 ? 788 ASP A C 1 ATOM 5775 O O . ASP A 1 762 ? -108.873 -22.765 17.773 1.00 106.30 ? 788 ASP A O 1 ATOM 5776 C CB . ASP A 1 762 ? -109.715 -25.484 19.641 1.00 141.57 ? 788 ASP A CB 1 ATOM 5777 C CG . ASP A 1 762 ? -109.948 -26.162 18.298 1.00 158.86 ? 788 ASP A CG 1 ATOM 5778 O OD1 . ASP A 1 762 ? -109.361 -25.726 17.284 1.00 172.03 ? 788 ASP A OD1 1 ATOM 5779 O OD2 . ASP A 1 762 ? -110.690 -27.168 18.269 1.00 159.77 ? 788 ASP A OD2 1 ATOM 5780 N N . GLU A 1 763 ? -110.146 -22.414 19.593 1.00 109.35 ? 789 GLU A N 1 ATOM 5781 C CA . GLU A 1 763 ? -110.750 -21.191 19.071 1.00 119.94 ? 789 GLU A CA 1 ATOM 5782 C C . GLU A 1 763 ? -109.748 -20.040 18.856 1.00 138.66 ? 789 GLU A C 1 ATOM 5783 O O . GLU A 1 763 ? -109.763 -19.384 17.814 1.00 131.75 ? 789 GLU A O 1 ATOM 5784 C CB . GLU A 1 763 ? -111.844 -20.704 20.014 1.00 111.10 ? 789 GLU A CB 1 ATOM 5785 C CG . GLU A 1 763 ? -113.047 -21.615 20.091 1.00 118.78 ? 789 GLU A CG 1 ATOM 5786 C CD . GLU A 1 763 ? -114.118 -21.067 21.014 1.00 125.80 ? 789 GLU A CD 1 ATOM 5787 O OE1 . GLU A 1 763 ? -113.769 -20.266 21.908 1.00 125.50 ? 789 GLU A OE1 1 ATOM 5788 O OE2 . GLU A 1 763 ? -115.299 -21.466 20.875 1.00 109.55 ? 789 GLU A OE2 1 ATOM 5789 N N . HIS A 1 764 ? -108.863 -19.818 19.825 1.00 146.92 ? 790 HIS A N 1 ATOM 5790 C CA . HIS A 1 764 ? -107.900 -18.725 19.733 1.00 131.36 ? 790 HIS A CA 1 ATOM 5791 C C . HIS A 1 764 ? -106.469 -19.115 19.355 1.00 133.14 ? 790 HIS A C 1 ATOM 5792 O O . HIS A 1 764 ? -105.628 -19.268 20.239 1.00 135.47 ? 790 HIS A O 1 ATOM 5793 C CB . HIS A 1 764 ? -107.831 -17.993 21.076 1.00 125.99 ? 790 HIS A CB 1 ATOM 5794 C CG . HIS A 1 764 ? -109.149 -17.486 21.568 1.00 119.68 ? 790 HIS A CG 1 ATOM 5795 N ND1 . HIS A 1 764 ? -109.960 -18.226 22.401 1.00 114.57 ? 790 HIS A ND1 1 ATOM 5796 C CD2 . HIS A 1 764 ? -109.763 -16.292 21.406 1.00 116.95 ? 790 HIS A CD2 1 ATOM 5797 C CE1 . HIS A 1 764 ? -111.024 -17.513 22.721 1.00 117.48 ? 790 HIS A CE1 1 ATOM 5798 N NE2 . HIS A 1 764 ? -110.931 -16.338 22.126 1.00 120.16 ? 790 HIS A NE2 1 ATOM 5799 N N . LEU A 1 765 ? -106.184 -19.287 18.062 1.00 143.30 ? 791 LEU A N 1 ATOM 5800 C CA . LEU A 1 765 ? -104.800 -19.598 17.635 1.00 140.94 ? 791 LEU A CA 1 ATOM 5801 C C . LEU A 1 765 ? -104.061 -18.250 17.525 1.00 130.79 ? 791 LEU A C 1 ATOM 5802 O O . LEU A 1 765 ? -102.874 -18.182 17.160 1.00 106.84 ? 791 LEU A O 1 ATOM 5803 C CB . LEU A 1 765 ? -104.719 -20.394 16.311 1.00 141.21 ? 791 LEU A CB 1 ATOM 5804 C CG . LEU A 1 765 ? -105.219 -21.852 16.272 1.00 131.89 ? 791 LEU A CG 1 ATOM 5805 C CD1 . LEU A 1 765 ? -106.711 -21.932 16.535 1.00 119.41 ? 791 LEU A CD1 1 ATOM 5806 C CD2 . LEU A 1 765 ? -104.892 -22.510 14.936 1.00 124.45 ? 791 LEU A CD2 1 ATOM 5807 N N . ASN A 1 766 ? -104.804 -17.187 17.847 1.00 105.97 ? 792 ASN A N 1 ATOM 5808 C CA . ASN A 1 766 ? -104.313 -15.814 17.839 1.00 118.32 ? 792 ASN A CA 1 ATOM 5809 C C . ASN A 1 766 ? -103.513 -15.446 19.116 1.00 121.35 ? 792 ASN A C 1 ATOM 5810 O O . ASN A 1 766 ? -102.873 -14.391 19.177 1.00 117.53 ? 792 ASN A O 1 ATOM 5811 C CB . ASN A 1 766 ? -105.500 -14.846 17.637 1.00 111.34 ? 792 ASN A CB 1 ATOM 5812 C CG . ASN A 1 766 ? -106.678 -15.161 18.555 1.00 120.82 ? 792 ASN A CG 1 ATOM 5813 O OD1 . ASN A 1 766 ? -106.941 -16.330 18.859 1.00 103.90 ? 792 ASN A OD1 1 ATOM 5814 N ND2 . ASN A 1 766 ? -107.461 -14.138 18.899 1.00 116.74 ? 792 ASN A ND2 1 ATOM 5815 N N . VAL A 1 767 ? -103.552 -16.324 20.119 1.00 112.28 ? 793 VAL A N 1 ATOM 5816 C CA . VAL A 1 767 ? -102.846 -16.110 21.381 1.00 93.87 ? 793 VAL A CA 1 ATOM 5817 C C . VAL A 1 767 ? -101.718 -17.140 21.485 1.00 96.10 ? 793 VAL A C 1 ATOM 5818 O O . VAL A 1 767 ? -101.967 -18.325 21.671 1.00 97.28 ? 793 VAL A O 1 ATOM 5819 C CB . VAL A 1 767 ? -103.790 -16.264 22.596 1.00 92.23 ? 793 VAL A CB 1 ATOM 5820 C CG1 . VAL A 1 767 ? -105.014 -15.369 22.443 1.00 83.54 ? 793 VAL A CG1 1 ATOM 5821 C CG2 . VAL A 1 767 ? -104.249 -17.702 22.762 1.00 104.55 ? 793 VAL A CG2 1 ATOM 5822 N N . LYS A 1 768 ? -100.481 -16.698 21.313 1.00 93.38 ? 794 LYS A N 1 ATOM 5823 C CA . LYS A 1 768 ? -99.343 -17.600 21.386 1.00 95.91 ? 794 LYS A CA 1 ATOM 5824 C C . LYS A 1 768 ? -99.265 -18.278 22.758 1.00 97.06 ? 794 LYS A C 1 ATOM 5825 O O . LYS A 1 768 ? -99.542 -17.664 23.788 1.00 106.97 ? 794 LYS A O 1 ATOM 5826 C CB . LYS A 1 768 ? -98.042 -16.825 21.135 1.00 115.22 ? 794 LYS A CB 1 ATOM 5827 C CG . LYS A 1 768 ? -96.762 -17.662 21.209 1.00 122.97 ? 794 LYS A CG 1 ATOM 5828 C CD . LYS A 1 768 ? -96.642 -18.679 20.083 1.00 133.44 ? 794 LYS A CD 1 ATOM 5829 C CE . LYS A 1 768 ? -96.542 -17.992 18.721 1.00 140.54 ? 794 LYS A CE 1 ATOM 5830 N NZ . LYS A 1 768 ? -96.371 -18.952 17.593 1.00 131.82 ? 794 LYS A NZ 1 ATOM 5831 N N . ILE A 1 769 ? -98.927 -19.559 22.752 1.00 90.88 ? 795 ILE A N 1 ATOM 5832 C CA . ILE A 1 769 ? -98.774 -20.330 23.975 1.00 87.63 ? 795 ILE A CA 1 ATOM 5833 C C . ILE A 1 769 ? -97.430 -21.010 23.808 1.00 87.71 ? 795 ILE A C 1 ATOM 5834 O O . ILE A 1 769 ? -97.353 -22.184 23.460 1.00 97.79 ? 795 ILE A O 1 ATOM 5835 C CB . ILE A 1 769 ? -99.853 -21.416 24.162 1.00 95.05 ? 795 ILE A CB 1 ATOM 5836 C CG1 . ILE A 1 769 ? -101.270 -20.828 24.137 1.00 96.11 ? 795 ILE A CG1 1 ATOM 5837 C CG2 . ILE A 1 769 ? -99.619 -22.164 25.472 1.00 96.96 ? 795 ILE A CG2 1 ATOM 5838 C CD1 . ILE A 1 769 ? -101.583 -19.874 25.263 1.00 109.67 ? 795 ILE A CD1 1 ATOM 5839 N N . PRO A 1 770 ? -96.357 -20.269 24.052 1.00 88.17 ? 796 PRO A N 1 ATOM 5840 C CA . PRO A 1 770 ? -95.077 -20.907 23.875 1.00 79.10 ? 796 PRO A CA 1 ATOM 5841 C C . PRO A 1 770 ? -94.942 -22.171 24.690 1.00 90.17 ? 796 PRO A C 1 ATOM 5842 O O . PRO A 1 770 ? -95.473 -22.275 25.800 1.00 105.05 ? 796 PRO A O 1 ATOM 5843 C CB . PRO A 1 770 ? -94.087 -19.852 24.357 1.00 89.25 ? 796 PRO A CB 1 ATOM 5844 C CG . PRO A 1 770 ? -94.868 -18.907 25.223 1.00 87.42 ? 796 PRO A CG 1 ATOM 5845 C CD . PRO A 1 770 ? -96.323 -19.215 25.077 1.00 92.84 ? 796 PRO A CD 1 ATOM 5846 N N . ARG A 1 771 ? -94.300 -23.157 24.101 1.00 99.17 ? 797 ARG A N 1 ATOM 5847 C CA . ARG A 1 771 ? -94.072 -24.423 24.764 1.00 110.71 ? 797 ARG A CA 1 ATOM 5848 C C . ARG A 1 771 ? -95.340 -25.219 25.090 1.00 116.48 ? 797 ARG A C 1 ATOM 5849 O O . ARG A 1 771 ? -95.545 -25.599 26.237 1.00 129.35 ? 797 ARG A O 1 ATOM 5850 C CB . ARG A 1 771 ? -93.217 -24.207 26.026 1.00 108.04 ? 797 ARG A CB 1 ATOM 5851 C CG . ARG A 1 771 ? -91.866 -23.556 25.725 1.00 114.77 ? 797 ARG A CG 1 ATOM 5852 C CD . ARG A 1 771 ? -91.041 -23.223 26.968 1.00 111.16 ? 797 ARG A CD 1 ATOM 5853 N NE . ARG A 1 771 ? -90.578 -24.388 27.721 1.00 109.64 ? 797 ARG A NE 1 ATOM 5854 C CZ . ARG A 1 771 ? -89.874 -24.317 28.854 1.00 115.13 ? 797 ARG A CZ 1 ATOM 5855 N NH1 . ARG A 1 771 ? -89.565 -23.138 29.385 1.00 126.93 ? 797 ARG A NH1 1 ATOM 5856 N NH2 . ARG A 1 771 ? -89.494 -25.426 29.472 1.00 109.56 ? 797 ARG A NH2 1 ATOM 5857 N N . LEU A 1 772 ? -96.203 -25.440 24.093 1.00 114.82 ? 798 LEU A N 1 ATOM 5858 C CA . LEU A 1 772 ? -97.413 -26.257 24.299 1.00 94.60 ? 798 LEU A CA 1 ATOM 5859 C C . LEU A 1 772 ? -96.932 -27.641 24.613 1.00 88.30 ? 798 LEU A C 1 ATOM 5860 O O . LEU A 1 772 ? -97.571 -28.392 25.339 1.00 88.02 ? 798 LEU A O 1 ATOM 5861 C CB . LEU A 1 772 ? -98.265 -26.330 23.045 1.00 101.46 ? 798 LEU A CB 1 ATOM 5862 C CG . LEU A 1 772 ? -99.055 -25.082 22.699 1.00 119.53 ? 798 LEU A CG 1 ATOM 5863 C CD1 . LEU A 1 772 ? -99.610 -25.159 21.288 1.00 132.04 ? 798 LEU A CD1 1 ATOM 5864 C CD2 . LEU A 1 772 ? -100.165 -24.892 23.721 1.00 113.00 ? 798 LEU A CD2 1 ATOM 5865 N N . VAL A 1 773 ? -95.779 -27.966 24.049 1.00 90.85 ? 799 VAL A N 1 ATOM 5866 C CA . VAL A 1 773 ? -95.155 -29.252 24.248 1.00 99.17 ? 799 VAL A CA 1 ATOM 5867 C C . VAL A 1 773 ? -94.925 -29.493 25.743 1.00 99.86 ? 799 VAL A C 1 ATOM 5868 O O . VAL A 1 773 ? -95.114 -30.605 26.234 1.00 105.96 ? 799 VAL A O 1 ATOM 5869 C CB . VAL A 1 773 ? -93.808 -29.314 23.512 1.00 103.77 ? 799 VAL A CB 1 ATOM 5870 C CG1 . VAL A 1 773 ? -93.203 -30.697 23.633 1.00 107.16 ? 799 VAL A CG1 1 ATOM 5871 C CG2 . VAL A 1 773 ? -93.989 -28.972 22.041 1.00 114.27 ? 799 VAL A CG2 1 ATOM 5872 N N . ASP A 1 774 ? -94.534 -28.442 26.464 1.00 112.34 ? 800 ASP A N 1 ATOM 5873 C CA . ASP A 1 774 ? -94.278 -28.544 27.912 1.00 112.70 ? 800 ASP A CA 1 ATOM 5874 C C . ASP A 1 774 ? -95.518 -28.409 28.799 1.00 100.50 ? 800 ASP A C 1 ATOM 5875 O O . ASP A 1 774 ? -95.437 -28.670 29.995 1.00 106.39 ? 800 ASP A O 1 ATOM 5876 C CB . ASP A 1 774 ? -93.156 -27.593 28.352 1.00 108.18 ? 800 ASP A CB 1 ATOM 5877 C CG . ASP A 1 774 ? -91.778 -28.025 27.829 1.00 117.38 ? 800 ASP A CG 1 ATOM 5878 O OD1 . ASP A 1 774 ? -91.543 -29.246 27.674 1.00 110.62 ? 800 ASP A OD1 1 ATOM 5879 O OD2 . ASP A 1 774 ? -90.895 -27.156 27.666 1.00 132.01 ? 800 ASP A OD2 1 ATOM 5880 N N . VAL A 1 775 ? -96.641 -27.962 28.238 1.00 97.02 ? 801 VAL A N 1 ATOM 5881 C CA . VAL A 1 775 ? -97.893 -27.870 29.015 1.00 100.52 ? 801 VAL A CA 1 ATOM 5882 C C . VAL A 1 775 ? -98.309 -29.347 29.140 1.00 102.19 ? 801 VAL A C 1 ATOM 5883 O O . VAL A 1 775 ? -98.674 -29.987 28.151 1.00 102.46 ? 801 VAL A O 1 ATOM 5884 C CB . VAL A 1 775 ? -98.966 -27.006 28.319 1.00 94.79 ? 801 VAL A CB 1 ATOM 5885 C CG1 . VAL A 1 775 ? -100.240 -26.984 29.132 1.00 92.26 ? 801 VAL A CG1 1 ATOM 5886 C CG2 . VAL A 1 775 ? -98.468 -25.579 28.146 1.00 89.05 ? 801 VAL A CG2 1 ATOM 5887 N N . ILE A 1 776 ? -98.247 -29.873 30.361 1.00 100.28 ? 802 ILE A N 1 ATOM 5888 C CA . ILE A 1 776 ? -98.501 -31.287 30.614 1.00 89.68 ? 802 ILE A CA 1 ATOM 5889 C C . ILE A 1 776 ? -99.528 -31.689 31.663 1.00 92.40 ? 802 ILE A C 1 ATOM 5890 O O . ILE A 1 776 ? -99.910 -30.909 32.535 1.00 107.23 ? 802 ILE A O 1 ATOM 5891 C CB . ILE A 1 776 ? -97.142 -31.937 30.970 1.00 92.00 ? 802 ILE A CB 1 ATOM 5892 C CG1 . ILE A 1 776 ? -96.243 -31.930 29.720 1.00 97.42 ? 802 ILE A CG1 1 ATOM 5893 C CG2 . ILE A 1 776 ? -97.303 -33.351 31.498 1.00 95.01 ? 802 ILE A CG2 1 ATOM 5894 C CD1 . ILE A 1 776 ? -94.852 -32.498 29.929 1.00 104.08 ? 802 ILE A CD1 1 ATOM 5895 N N . CYS A 1 777 ? -99.991 -32.930 31.521 1.00 96.52 ? 803 CYS A N 1 ATOM 5896 C CA . CYS A 1 777 ? -100.963 -33.529 32.418 1.00 92.98 ? 803 CYS A CA 1 ATOM 5897 C C . CYS A 1 777 ? -100.290 -34.070 33.659 1.00 93.66 ? 803 CYS A C 1 ATOM 5898 O O . CYS A 1 777 ? -99.386 -34.919 33.577 1.00 81.26 ? 803 CYS A O 1 ATOM 5899 C CB . CYS A 1 777 ? -101.683 -34.701 31.732 1.00 108.40 ? 803 CYS A CB 1 ATOM 5900 S SG . CYS A 1 777 ? -102.684 -34.298 30.287 1.00 100.09 ? 803 CYS A SG 1 ATOM 5901 N N . ALA A 1 778 ? -100.736 -33.578 34.807 1.00 101.87 ? 804 ALA A N 1 ATOM 5902 C CA . ALA A 1 778 ? -100.215 -34.013 36.095 1.00 109.90 ? 804 ALA A CA 1 ATOM 5903 C C . ALA A 1 778 ? -100.948 -35.281 36.485 1.00 114.82 ? 804 ALA A C 1 ATOM 5904 O O . ALA A 1 778 ? -100.362 -36.209 37.039 1.00 126.25 ? 804 ALA A O 1 ATOM 5905 C CB . ALA A 1 778 ? -100.453 -32.941 37.144 1.00 106.05 ? 804 ALA A CB 1 ATOM 5906 N N . SER A 1 779 ? -102.246 -35.296 36.194 1.00 114.43 ? 805 SER A N 1 ATOM 5907 C CA . SER A 1 779 ? -103.100 -36.430 36.500 1.00 109.05 ? 805 SER A CA 1 ATOM 5908 C C . SER A 1 779 ? -104.237 -36.524 35.469 1.00 116.56 ? 805 SER A C 1 ATOM 5909 O O . SER A 1 779 ? -104.530 -35.540 34.782 1.00 105.30 ? 805 SER A O 1 ATOM 5910 C CB . SER A 1 779 ? -103.674 -36.267 37.903 1.00 95.03 ? 805 SER A CB 1 ATOM 5911 O OG . SER A 1 779 ? -104.499 -35.121 37.974 1.00 89.18 ? 805 SER A OG 1 ATOM 5912 N N . PRO A 1 780 ? -104.895 -37.688 35.383 1.00 125.37 ? 806 PRO A N 1 ATOM 5913 C CA . PRO A 1 780 ? -104.575 -38.845 36.233 1.00 112.69 ? 806 PRO A CA 1 ATOM 5914 C C . PRO A 1 780 ? -103.533 -39.813 35.647 1.00 110.35 ? 806 PRO A C 1 ATOM 5915 O O . PRO A 1 780 ? -103.158 -39.707 34.480 1.00 103.88 ? 806 PRO A O 1 ATOM 5916 C CB . PRO A 1 780 ? -105.934 -39.543 36.413 1.00 118.66 ? 806 PRO A CB 1 ATOM 5917 C CG . PRO A 1 780 ? -106.950 -38.689 35.698 1.00 116.46 ? 806 PRO A CG 1 ATOM 5918 C CD . PRO A 1 780 ? -106.190 -37.868 34.709 1.00 118.11 ? 806 PRO A CD 1 ATOM 5919 N N . GLY A 1 781 ? -103.222 -40.891 36.338 1.00 111.32 ? 807 GLY A N 1 ATOM 5920 C CA . GLY A 1 781 ? -102.007 -41.614 36.042 1.00 101.39 ? 807 GLY A CA 1 ATOM 5921 C C . GLY A 1 781 ? -101.840 -42.103 34.620 1.00 107.01 ? 807 GLY A C 1 ATOM 5922 O O . GLY A 1 781 ? -100.763 -41.980 34.076 1.00 105.64 ? 807 GLY A O 1 ATOM 5923 N N . ASP A 1 782 ? -102.888 -42.604 34.001 1.00 128.29 ? 808 ASP A N 1 ATOM 5924 C CA . ASP A 1 782 ? -102.743 -42.996 32.616 1.00 134.66 ? 808 ASP A CA 1 ATOM 5925 C C . ASP A 1 782 ? -102.411 -41.740 31.856 1.00 122.63 ? 808 ASP A C 1 ATOM 5926 O O . ASP A 1 782 ? -101.613 -41.746 30.931 1.00 120.28 ? 808 ASP A O 1 ATOM 5927 C CB . ASP A 1 782 ? -104.013 -43.650 32.062 1.00 136.25 ? 808 ASP A CB 1 ATOM 5928 C CG . ASP A 1 782 ? -105.258 -43.241 32.809 1.00 144.00 ? 808 ASP A CG 1 ATOM 5929 O OD1 . ASP A 1 782 ? -105.287 -43.391 34.047 1.00 145.54 ? 808 ASP A OD1 1 ATOM 5930 O OD2 . ASP A 1 782 ? -106.212 -42.773 32.154 1.00 132.37 ? 808 ASP A OD2 1 ATOM 5931 N N . GLN A 1 783 ? -103.067 -40.665 32.252 1.00 125.28 ? 809 GLN A N 1 ATOM 5932 C CA . GLN A 1 783 ? -102.868 -39.360 31.654 1.00 134.98 ? 809 GLN A CA 1 ATOM 5933 C C . GLN A 1 783 ? -101.491 -38.746 31.857 1.00 134.15 ? 809 GLN A C 1 ATOM 5934 O O . GLN A 1 783 ? -100.968 -38.083 30.974 1.00 124.89 ? 809 GLN A O 1 ATOM 5935 C CB . GLN A 1 783 ? -103.954 -38.399 32.101 1.00 143.37 ? 809 GLN A CB 1 ATOM 5936 C CG . GLN A 1 783 ? -104.797 -37.889 30.951 1.00 145.07 ? 809 GLN A CG 1 ATOM 5937 C CD . GLN A 1 783 ? -105.158 -38.981 29.971 1.00 142.51 ? 809 GLN A CD 1 ATOM 5938 O OE1 . GLN A 1 783 ? -104.291 -39.609 29.370 1.00 133.30 ? 809 GLN A OE1 1 ATOM 5939 N NE2 . GLN A 1 783 ? -106.448 -39.213 29.805 1.00 140.42 ? 809 GLN A NE2 1 ATOM 5940 N N . ARG A 1 784 ? -100.901 -38.956 33.022 1.00 135.82 ? 810 ARG A N 1 ATOM 5941 C CA . ARG A 1 784 ? -99.752 -38.165 33.414 1.00 130.30 ? 810 ARG A CA 1 ATOM 5942 C C . ARG A 1 784 ? -98.635 -38.267 32.399 1.00 125.63 ? 810 ARG A C 1 ATOM 5943 O O . ARG A 1 784 ? -98.348 -39.326 31.862 1.00 100.77 ? 810 ARG A O 1 ATOM 5944 C CB . ARG A 1 784 ? -99.253 -38.568 34.807 1.00 120.76 ? 810 ARG A CB 1 ATOM 5945 C CG . ARG A 1 784 ? -97.831 -38.141 35.132 1.00 123.62 ? 810 ARG A CG 1 ATOM 5946 C CD . ARG A 1 784 ? -97.458 -38.414 36.578 1.00 126.10 ? 810 ARG A CD 1 ATOM 5947 N NE . ARG A 1 784 ? -97.112 -37.192 37.297 1.00 126.86 ? 810 ARG A NE 1 ATOM 5948 C CZ . ARG A 1 784 ? -95.911 -36.929 37.798 1.00 126.85 ? 810 ARG A CZ 1 ATOM 5949 N NH1 . ARG A 1 784 ? -95.691 -35.791 38.433 1.00 120.10 ? 810 ARG A NH1 1 ATOM 5950 N NH2 . ARG A 1 784 ? -94.928 -37.804 37.667 1.00 136.13 ? 810 ARG A NH2 1 ATOM 5951 N N . GLY A 1 785 ? -98.014 -37.120 32.161 1.00 112.71 ? 811 GLY A N 1 ATOM 5952 C CA . GLY A 1 785 ? -96.908 -36.990 31.244 1.00 119.18 ? 811 GLY A CA 1 ATOM 5953 C C . GLY A 1 785 ? -97.297 -36.647 29.829 1.00 125.59 ? 811 GLY A C 1 ATOM 5954 O O . GLY A 1 785 ? -96.442 -36.433 28.984 1.00 118.27 ? 811 GLY A O 1 ATOM 5955 N N . LYS A 1 786 ? -98.585 -36.540 29.572 1.00 130.02 ? 812 LYS A N 1 ATOM 5956 C CA . LYS A 1 786 ? -99.031 -36.326 28.216 1.00 137.91 ? 812 LYS A CA 1 ATOM 5957 C C . LYS A 1 786 ? -99.412 -34.882 28.010 1.00 119.74 ? 812 LYS A C 1 ATOM 5958 O O . LYS A 1 786 ? -100.120 -34.309 28.813 1.00 109.45 ? 812 LYS A O 1 ATOM 5959 C CB . LYS A 1 786 ? -100.210 -37.246 27.896 1.00 153.97 ? 812 LYS A CB 1 ATOM 5960 C CG . LYS A 1 786 ? -99.839 -38.471 27.074 1.00 156.67 ? 812 LYS A CG 1 ATOM 5961 C CD . LYS A 1 786 ? -101.071 -39.265 26.664 1.00 164.69 ? 812 LYS A CD 1 ATOM 5962 C CE . LYS A 1 786 ? -100.815 -40.113 25.425 1.00 159.11 ? 812 LYS A CE 1 ATOM 5963 N NZ . LYS A 1 786 ? -101.989 -40.947 25.030 1.00 151.12 ? 812 LYS A NZ 1 ATOM 5964 N N . SER A 1 787 ? -98.934 -34.293 26.929 1.00 106.00 ? 813 SER A N 1 ATOM 5965 C CA . SER A 1 787 ? -99.225 -32.908 26.661 1.00 102.45 ? 813 SER A CA 1 ATOM 5966 C C . SER A 1 787 ? -100.709 -32.728 26.490 1.00 99.02 ? 813 SER A C 1 ATOM 5967 O O . SER A 1 787 ? -101.357 -33.514 25.835 1.00 105.71 ? 813 SER A O 1 ATOM 5968 C CB . SER A 1 787 ? -98.521 -32.483 25.394 1.00 104.12 ? 813 SER A CB 1 ATOM 5969 O OG . SER A 1 787 ? -99.050 -31.265 24.938 1.00 119.32 ? 813 SER A OG 1 ATOM 5970 N N . ILE A 1 788 ? -101.248 -31.666 27.057 1.00 93.35 ? 814 ILE A N 1 ATOM 5971 C CA . ILE A 1 788 ? -102.719 -31.496 27.084 1.00 96.71 ? 814 ILE A CA 1 ATOM 5972 C C . ILE A 1 788 ? -103.380 -31.362 25.726 1.00 97.12 ? 814 ILE A C 1 ATOM 5973 O O . ILE A 1 788 ? -104.565 -31.048 25.643 1.00 102.31 ? 814 ILE A O 1 ATOM 5974 C CB . ILE A 1 788 ? -103.190 -30.309 27.941 1.00 105.47 ? 814 ILE A CB 1 ATOM 5975 C CG1 . ILE A 1 788 ? -102.783 -28.987 27.296 1.00 112.35 ? 814 ILE A CG1 1 ATOM 5976 C CG2 . ILE A 1 788 ? -102.692 -30.454 29.373 1.00 102.84 ? 814 ILE A CG2 1 ATOM 5977 C CD1 . ILE A 1 788 ? -103.308 -27.781 28.038 1.00 114.65 ? 814 ILE A CD1 1 ATOM 5978 N N . VAL A 1 789 ? -102.598 -31.503 24.667 1.00 108.80 ? 815 VAL A N 1 ATOM 5979 C CA . VAL A 1 789 ? -103.129 -31.434 23.310 1.00 113.52 ? 815 VAL A CA 1 ATOM 5980 C C . VAL A 1 789 ? -102.995 -32.805 22.645 1.00 122.66 ? 815 VAL A C 1 ATOM 5981 O O . VAL A 1 789 ? -103.822 -33.193 21.818 1.00 123.11 ? 815 VAL A O 1 ATOM 5982 C CB . VAL A 1 789 ? -102.477 -30.314 22.478 1.00 97.60 ? 815 VAL A CB 1 ATOM 5983 C CG1 . VAL A 1 789 ? -102.912 -28.960 23.008 1.00 91.59 ? 815 VAL A CG1 1 ATOM 5984 C CG2 . VAL A 1 789 ? -100.960 -30.439 22.504 1.00 86.48 ? 815 VAL A CG2 1 ATOM 5985 N N . SER A 1 790 ? -102.035 -33.573 23.111 1.00 118.67 ? 816 SER A N 1 ATOM 5986 C CA . SER A 1 790 ? -101.841 -34.905 22.609 1.00 125.99 ? 816 SER A CA 1 ATOM 5987 C C . SER A 1 790 ? -103.055 -35.748 22.973 1.00 140.41 ? 816 SER A C 1 ATOM 5988 O O . SER A 1 790 ? -103.239 -36.855 22.466 1.00 149.52 ? 816 SER A O 1 ATOM 5989 C CB . SER A 1 790 ? -100.582 -35.508 23.210 1.00 132.09 ? 816 SER A CB 1 ATOM 5990 O OG . SER A 1 790 ? -100.547 -36.909 23.014 1.00 143.66 ? 816 SER A OG 1 ATOM 5991 N N . LEU A 1 791 ? -103.877 -35.241 23.876 1.00 134.07 ? 817 LEU A N 1 ATOM 5992 C CA . LEU A 1 791 ? -104.910 -36.046 24.486 1.00 137.77 ? 817 LEU A CA 1 ATOM 5993 C C . LEU A 1 791 ? -105.855 -36.665 23.488 1.00 147.52 ? 817 LEU A C 1 ATOM 5994 O O . LEU A 1 791 ? -106.338 -36.008 22.577 1.00 144.19 ? 817 LEU A O 1 ATOM 5995 C CB . LEU A 1 791 ? -105.737 -35.179 25.414 1.00 129.35 ? 817 LEU A CB 1 ATOM 5996 C CG . LEU A 1 791 ? -105.071 -34.900 26.742 1.00 124.28 ? 817 LEU A CG 1 ATOM 5997 C CD1 . LEU A 1 791 ? -106.017 -34.157 27.660 1.00 109.59 ? 817 LEU A CD1 1 ATOM 5998 C CD2 . LEU A 1 791 ? -104.638 -36.212 27.350 1.00 121.50 ? 817 LEU A CD2 1 ATOM 5999 N N . GLU A 1 792 ? -106.132 -37.944 23.705 1.00 156.40 ? 818 GLU A N 1 ATOM 6000 C CA . GLU A 1 792 ? -107.105 -38.679 22.929 1.00 144.50 ? 818 GLU A CA 1 ATOM 6001 C C . GLU A 1 792 ? -108.421 -38.385 23.577 1.00 133.22 ? 818 GLU A C 1 ATOM 6002 O O . GLU A 1 792 ? -108.974 -39.200 24.295 1.00 138.79 ? 818 GLU A O 1 ATOM 6003 C CB . GLU A 1 792 ? -106.826 -40.180 22.978 1.00 143.84 ? 818 GLU A CB 1 ATOM 6004 C CG . GLU A 1 792 ? -105.879 -40.632 24.079 1.00 145.75 ? 818 GLU A CG 1 ATOM 6005 C CD . GLU A 1 792 ? -106.356 -40.242 25.455 1.00 136.25 ? 818 GLU A CD 1 ATOM 6006 O OE1 . GLU A 1 792 ? -106.796 -39.094 25.620 1.00 121.26 ? 818 GLU A OE1 1 ATOM 6007 O OE2 . GLU A 1 792 ? -106.296 -41.086 26.366 1.00 118.69 ? 818 GLU A OE2 1 ATOM 6008 N N . LEU A 1 793 ? -108.920 -37.194 23.331 1.00 124.26 ? 819 LEU A N 1 ATOM 6009 C CA . LEU A 1 793 ? -110.088 -36.724 24.035 1.00 143.09 ? 819 LEU A CA 1 ATOM 6010 C C . LEU A 1 793 ? -111.288 -37.600 23.755 1.00 157.25 ? 819 LEU A C 1 ATOM 6011 O O . LEU A 1 793 ? -112.162 -37.781 24.601 1.00 144.13 ? 819 LEU A O 1 ATOM 6012 C CB . LEU A 1 793 ? -110.390 -35.288 23.654 1.00 152.24 ? 819 LEU A CB 1 ATOM 6013 C CG . LEU A 1 793 ? -111.218 -34.537 24.694 1.00 171.34 ? 819 LEU A CG 1 ATOM 6014 C CD1 . LEU A 1 793 ? -110.419 -34.309 25.963 1.00 174.52 ? 819 LEU A CD1 1 ATOM 6015 C CD2 . LEU A 1 793 ? -111.702 -33.209 24.140 1.00 175.78 ? 819 LEU A CD2 1 ATOM 6016 N N . THR A 1 794 ? -111.361 -38.089 22.528 1.00 166.49 ? 820 THR A N 1 ATOM 6017 C CA . THR A 1 794 ? -112.607 -38.705 22.031 1.00 147.49 ? 820 THR A CA 1 ATOM 6018 C C . THR A 1 794 ? -113.274 -39.651 23.041 1.00 151.24 ? 820 THR A C 1 ATOM 6019 O O . THR A 1 794 ? -114.497 -39.614 23.219 1.00 152.83 ? 820 THR A O 1 ATOM 6020 C CB . THR A 1 794 ? -112.375 -39.464 20.711 1.00 139.01 ? 820 THR A CB 1 ATOM 6021 O OG1 . THR A 1 794 ? -111.457 -40.543 20.925 1.00 132.98 ? 820 THR A OG1 1 ATOM 6022 C CG2 . THR A 1 794 ? -111.830 -38.522 19.633 1.00 138.97 ? 820 THR A CG2 1 ATOM 6023 N N . THR A 1 795 ? -112.461 -40.463 23.721 1.00 155.79 ? 821 THR A N 1 ATOM 6024 C CA . THR A 1 795 ? -112.942 -41.429 24.726 1.00 141.75 ? 821 THR A CA 1 ATOM 6025 C C . THR A 1 795 ? -113.761 -40.721 25.817 1.00 135.14 ? 821 THR A C 1 ATOM 6026 O O . THR A 1 795 ? -114.280 -41.351 26.739 1.00 113.68 ? 821 THR A O 1 ATOM 6027 C CB . THR A 1 795 ? -111.747 -42.129 25.415 1.00 140.30 ? 821 THR A CB 1 ATOM 6028 O OG1 . THR A 1 795 ? -110.834 -42.623 24.428 1.00 144.90 ? 821 THR A OG1 1 ATOM 6029 C CG2 . THR A 1 795 ? -112.212 -43.276 26.319 1.00 137.55 ? 821 THR A CG2 1 ATOM 6030 N N . CYS A 1 796 ? -113.874 -39.406 25.697 1.00 136.82 ? 822 CYS A N 1 ATOM 6031 C CA . CYS A 1 796 ? -114.592 -38.604 26.661 1.00 135.18 ? 822 CYS A CA 1 ATOM 6032 C C . CYS A 1 796 ? -116.107 -38.574 26.408 1.00 123.83 ? 822 CYS A C 1 ATOM 6033 O O . CYS A 1 796 ? -116.878 -38.478 27.361 1.00 105.46 ? 822 CYS A O 1 ATOM 6034 C CB . CYS A 1 796 ? -113.989 -37.191 26.672 1.00 137.73 ? 822 CYS A CB 1 ATOM 6035 S SG . CYS A 1 796 ? -114.722 -36.021 27.831 1.00 168.19 ? 822 CYS A SG 1 ATOM 6036 N N . VAL A 1 797 ? -116.523 -38.698 25.141 1.00 130.91 ? 823 VAL A N 1 ATOM 6037 C CA . VAL A 1 797 ? -117.966 -38.679 24.761 1.00 142.03 ? 823 VAL A CA 1 ATOM 6038 C C . VAL A 1 797 ? -118.788 -37.689 25.593 1.00 127.47 ? 823 VAL A C 1 ATOM 6039 O O . VAL A 1 797 ? -118.823 -36.497 25.298 1.00 115.90 ? 823 VAL A O 1 ATOM 6040 C CB . VAL A 1 797 ? -118.629 -40.083 24.859 1.00 126.09 ? 823 VAL A CB 1 ATOM 6041 C CG1 . VAL A 1 797 ? -120.139 -39.982 24.658 1.00 97.02 ? 823 VAL A CG1 1 ATOM 6042 C CG2 . VAL A 1 797 ? -118.001 -41.050 23.860 1.00 117.40 ? 823 VAL A CG2 1 HETATM 6043 C C1 . NAG B 2 . ? -48.633 -17.177 -9.677 1.00 106.28 ? 901 NAG A C1 1 HETATM 6044 C C2 . NAG B 2 . ? -49.274 -16.695 -10.973 1.00 102.78 ? 901 NAG A C2 1 HETATM 6045 C C3 . NAG B 2 . ? -48.300 -16.811 -12.140 1.00 104.06 ? 901 NAG A C3 1 HETATM 6046 C C4 . NAG B 2 . ? -46.952 -16.192 -11.789 1.00 111.93 ? 901 NAG A C4 1 HETATM 6047 C C5 . NAG B 2 . ? -46.450 -16.704 -10.444 1.00 114.19 ? 901 NAG A C5 1 HETATM 6048 C C6 . NAG B 2 . ? -45.140 -16.028 -10.058 1.00 116.48 ? 901 NAG A C6 1 HETATM 6049 C C7 . NAG B 2 . ? -51.636 -16.870 -11.500 1.00 102.70 ? 901 NAG A C7 1 HETATM 6050 C C8 . NAG B 2 . ? -52.751 -17.779 -11.924 1.00 83.51 ? 901 NAG A C8 1 HETATM 6051 N N2 . NAG B 2 . ? -50.472 -17.463 -11.249 1.00 122.09 ? 901 NAG A N2 1 HETATM 6052 O O3 . NAG B 2 . ? -48.847 -16.147 -13.285 1.00 104.69 ? 901 NAG A O3 1 HETATM 6053 O O4 . NAG B 2 . ? -46.000 -16.515 -12.809 1.00 110.61 ? 901 NAG A O4 1 HETATM 6054 O O5 . NAG B 2 . ? -47.431 -16.447 -9.442 1.00 118.78 ? 901 NAG A O5 1 HETATM 6055 O O6 . NAG B 2 . ? -44.328 -15.856 -11.225 1.00 122.09 ? 901 NAG A O6 1 HETATM 6056 O O7 . NAG B 2 . ? -51.787 -15.664 -11.391 1.00 95.36 ? 901 NAG A O7 1 HETATM 6057 C C1 . NAG C 2 . ? -58.931 -16.555 11.949 1.00 44.28 ? 902 NAG A C1 1 HETATM 6058 C C2 . NAG C 2 . ? -60.094 -17.177 12.728 1.00 47.83 ? 902 NAG A C2 1 HETATM 6059 C C3 . NAG C 2 . ? -61.416 -17.067 12.003 1.00 54.48 ? 902 NAG A C3 1 HETATM 6060 C C4 . NAG C 2 . ? -61.628 -15.634 11.481 1.00 48.43 ? 902 NAG A C4 1 HETATM 6061 C C5 . NAG C 2 . ? -60.333 -15.213 10.810 1.00 53.25 ? 902 NAG A C5 1 HETATM 6062 C C6 . NAG C 2 . ? -60.350 -13.869 10.123 1.00 52.91 ? 902 NAG A C6 1 HETATM 6063 C C7 . NAG C 2 . ? -60.014 -19.109 14.148 1.00 60.13 ? 902 NAG A C7 1 HETATM 6064 C C8 . NAG C 2 . ? -59.663 -20.561 14.297 1.00 59.09 ? 902 NAG A C8 1 HETATM 6065 N N2 . NAG C 2 . ? -59.826 -18.566 12.963 1.00 62.03 ? 902 NAG A N2 1 HETATM 6066 O O3 . NAG C 2 . ? -62.463 -17.565 12.833 1.00 50.04 ? 902 NAG A O3 1 HETATM 6067 O O4 . NAG C 2 . ? -62.620 -15.662 10.484 1.00 52.90 ? 902 NAG A O4 1 HETATM 6068 O O5 . NAG C 2 . ? -59.337 -15.228 11.776 1.00 48.31 ? 902 NAG A O5 1 HETATM 6069 O O6 . NAG C 2 . ? -61.165 -13.060 10.921 1.00 73.88 ? 902 NAG A O6 1 HETATM 6070 O O7 . NAG C 2 . ? -60.425 -18.457 15.087 1.00 55.67 ? 902 NAG A O7 1 HETATM 6071 C C1 . NAG D 2 . ? -63.929 -15.475 11.031 1.00 57.13 ? 903 NAG A C1 1 HETATM 6072 C C2 . NAG D 2 . ? -64.877 -15.032 9.937 1.00 57.17 ? 903 NAG A C2 1 HETATM 6073 C C3 . NAG D 2 . ? -66.206 -14.722 10.541 1.00 54.83 ? 903 NAG A C3 1 HETATM 6074 C C4 . NAG D 2 . ? -66.731 -15.882 11.333 1.00 63.96 ? 903 NAG A C4 1 HETATM 6075 C C5 . NAG D 2 . ? -65.652 -16.372 12.276 1.00 68.84 ? 903 NAG A C5 1 HETATM 6076 C C6 . NAG D 2 . ? -66.125 -17.616 13.020 1.00 67.09 ? 903 NAG A C6 1 HETATM 6077 C C7 . NAG D 2 . ? -64.559 -13.575 8.020 1.00 61.80 ? 903 NAG A C7 1 HETATM 6078 C C8 . NAG D 2 . ? -64.094 -12.224 7.548 1.00 52.95 ? 903 NAG A C8 1 HETATM 6079 N N2 . NAG D 2 . ? -64.447 -13.801 9.330 1.00 59.59 ? 903 NAG A N2 1 HETATM 6080 O O3 . NAG D 2 . ? -67.101 -14.401 9.521 1.00 60.29 ? 903 NAG A O3 1 HETATM 6081 O O4 . NAG D 2 . ? -67.766 -15.348 12.114 1.00 74.23 ? 903 NAG A O4 1 HETATM 6082 O O5 . NAG D 2 . ? -64.452 -16.647 11.564 1.00 60.67 ? 903 NAG A O5 1 HETATM 6083 O O6 . NAG D 2 . ? -65.980 -18.754 12.188 1.00 72.00 ? 903 NAG A O6 1 HETATM 6084 O O7 . NAG D 2 . ? -65.010 -14.401 7.221 1.00 62.59 ? 903 NAG A O7 1 HETATM 6085 C C1 . BMA E 3 . ? -69.008 -15.981 11.789 1.00 81.29 ? 904 BMA A C1 1 HETATM 6086 C C2 . BMA E 3 . ? -69.950 -15.830 12.984 1.00 89.92 ? 904 BMA A C2 1 HETATM 6087 C C3 . BMA E 3 . ? -71.326 -16.406 12.679 1.00 98.41 ? 904 BMA A C3 1 HETATM 6088 C C4 . BMA E 3 . ? -71.845 -15.762 11.415 1.00 101.40 ? 904 BMA A C4 1 HETATM 6089 C C5 . BMA E 3 . ? -70.856 -15.958 10.268 1.00 109.69 ? 904 BMA A C5 1 HETATM 6090 C C6 . BMA E 3 . ? -71.399 -15.309 8.993 1.00 115.42 ? 904 BMA A C6 1 HETATM 6091 O O2 . BMA E 3 . ? -70.101 -14.443 13.321 1.00 68.47 ? 904 BMA A O2 1 HETATM 6092 O O3 . BMA E 3 . ? -72.249 -16.148 13.744 1.00 105.35 ? 904 BMA A O3 1 HETATM 6093 O O4 . BMA E 3 . ? -73.100 -16.343 11.077 1.00 103.14 ? 904 BMA A O4 1 HETATM 6094 O O5 . BMA E 3 . ? -69.573 -15.405 10.613 1.00 95.67 ? 904 BMA A O5 1 HETATM 6095 O O6 . BMA E 3 . ? -72.335 -14.268 9.324 1.00 130.41 ? 904 BMA A O6 1 HETATM 6096 C C1 . MAN F 4 . ? -72.595 -13.427 8.179 1.00 138.30 ? 905 MAN A C1 1 HETATM 6097 C C2 . MAN F 4 . ? -71.513 -12.342 8.082 1.00 135.92 ? 905 MAN A C2 1 HETATM 6098 C C3 . MAN F 4 . ? -71.662 -11.251 9.153 1.00 138.20 ? 905 MAN A C3 1 HETATM 6099 C C4 . MAN F 4 . ? -73.107 -10.768 9.268 1.00 122.89 ? 905 MAN A C4 1 HETATM 6100 C C5 . MAN F 4 . ? -74.040 -11.981 9.364 1.00 118.44 ? 905 MAN A C5 1 HETATM 6101 C C6 . MAN F 4 . ? -75.493 -11.565 9.462 1.00 114.21 ? 905 MAN A C6 1 HETATM 6102 O O2 . MAN F 4 . ? -71.539 -11.775 6.793 1.00 135.82 ? 905 MAN A O2 1 HETATM 6103 O O3 . MAN F 4 . ? -70.827 -10.150 8.861 1.00 129.30 ? 905 MAN A O3 1 HETATM 6104 O O4 . MAN F 4 . ? -73.244 -9.899 10.384 1.00 100.36 ? 905 MAN A O4 1 HETATM 6105 O O5 . MAN F 4 . ? -73.881 -12.829 8.242 1.00 124.11 ? 905 MAN A O5 1 HETATM 6106 O O6 . MAN F 4 . ? -75.932 -11.909 10.753 1.00 102.47 ? 905 MAN A O6 1 HETATM 6107 C C1 . NAG G 2 . ? -59.437 8.124 9.349 1.00 72.13 ? 906 NAG A C1 1 HETATM 6108 C C2 . NAG G 2 . ? -60.874 7.978 8.854 1.00 72.76 ? 906 NAG A C2 1 HETATM 6109 C C3 . NAG G 2 . ? -61.124 8.989 7.744 1.00 74.30 ? 906 NAG A C3 1 HETATM 6110 C C4 . NAG G 2 . ? -60.795 10.388 8.248 1.00 73.03 ? 906 NAG A C4 1 HETATM 6111 C C5 . NAG G 2 . ? -59.333 10.399 8.694 1.00 75.03 ? 906 NAG A C5 1 HETATM 6112 C C6 . NAG G 2 . ? -58.854 11.743 9.215 1.00 77.74 ? 906 NAG A C6 1 HETATM 6113 C C7 . NAG G 2 . ? -62.151 5.932 8.461 1.00 72.37 ? 906 NAG A C7 1 HETATM 6114 C C8 . NAG G 2 . ? -62.178 4.616 7.735 1.00 64.21 ? 906 NAG A C8 1 HETATM 6115 N N2 . NAG G 2 . ? -61.066 6.670 8.270 1.00 73.34 ? 906 NAG A N2 1 HETATM 6116 O O3 . NAG G 2 . ? -62.452 8.875 7.273 1.00 81.87 ? 906 NAG A O3 1 HETATM 6117 O O4 . NAG G 2 . ? -61.034 11.317 7.222 1.00 74.15 ? 906 NAG A O4 1 HETATM 6118 O O5 . NAG G 2 . ? -59.167 9.462 9.724 1.00 71.98 ? 906 NAG A O5 1 HETATM 6119 O O6 . NAG G 2 . ? -59.443 11.978 10.468 1.00 80.15 ? 906 NAG A O6 1 HETATM 6120 O O7 . NAG G 2 . ? -63.074 6.270 9.203 1.00 82.63 ? 906 NAG A O7 1 HETATM 6121 C C1 . NAG H 2 . ? -46.907 13.946 20.152 1.00 90.35 ? 907 NAG A C1 1 HETATM 6122 C C2 . NAG H 2 . ? -45.529 13.498 20.606 1.00 92.52 ? 907 NAG A C2 1 HETATM 6123 C C3 . NAG H 2 . ? -44.525 13.865 19.531 1.00 97.82 ? 907 NAG A C3 1 HETATM 6124 C C4 . NAG H 2 . ? -44.911 13.229 18.216 1.00 99.01 ? 907 NAG A C4 1 HETATM 6125 C C5 . NAG H 2 . ? -46.366 13.510 17.856 1.00 97.74 ? 907 NAG A C5 1 HETATM 6126 C C6 . NAG H 2 . ? -46.786 12.586 16.721 1.00 95.87 ? 907 NAG A C6 1 HETATM 6127 C C7 . NAG H 2 . ? -44.445 13.516 22.743 1.00 91.83 ? 907 NAG A C7 1 HETATM 6128 C C8 . NAG H 2 . ? -44.067 14.323 23.950 1.00 105.72 ? 907 NAG A C8 1 HETATM 6129 N N2 . NAG H 2 . ? -45.156 14.153 21.846 1.00 81.86 ? 907 NAG A N2 1 HETATM 6130 O O3 . NAG H 2 . ? -43.245 13.413 19.889 1.00 116.23 ? 907 NAG A O3 1 HETATM 6131 O O4 . NAG H 2 . ? -44.056 13.757 17.223 1.00 108.71 ? 907 NAG A O4 1 HETATM 6132 O O5 . NAG H 2 . ? -47.250 13.305 18.942 1.00 85.70 ? 907 NAG A O5 1 HETATM 6133 O O6 . NAG H 2 . ? -48.049 12.985 16.241 1.00 89.35 ? 907 NAG A O6 1 HETATM 6134 O O7 . NAG H 2 . ? -44.117 12.325 22.602 1.00 96.59 ? 907 NAG A O7 1 HETATM 6135 C C1 . NAG I 2 . ? -65.940 -3.419 33.790 1.00 45.62 ? 908 NAG A C1 1 HETATM 6136 C C2 . NAG I 2 . ? -67.098 -3.852 32.883 1.00 42.55 ? 908 NAG A C2 1 HETATM 6137 C C3 . NAG I 2 . ? -67.740 -5.090 33.457 1.00 54.56 ? 908 NAG A C3 1 HETATM 6138 C C4 . NAG I 2 . ? -66.709 -6.181 33.768 1.00 54.44 ? 908 NAG A C4 1 HETATM 6139 C C5 . NAG I 2 . ? -65.514 -5.571 34.507 1.00 52.22 ? 908 NAG A C5 1 HETATM 6140 C C6 . NAG I 2 . ? -64.444 -6.612 34.697 1.00 46.62 ? 908 NAG A C6 1 HETATM 6141 C C7 . NAG I 2 . ? -68.287 -2.060 31.655 1.00 43.74 ? 908 NAG A C7 1 HETATM 6142 C C8 . NAG I 2 . ? -69.286 -0.956 31.782 1.00 43.48 ? 908 NAG A C8 1 HETATM 6143 N N2 . NAG I 2 . ? -68.062 -2.787 32.773 1.00 45.97 ? 908 NAG A N2 1 HETATM 6144 O O3 . NAG I 2 . ? -68.729 -5.540 32.565 1.00 52.26 ? 908 NAG A O3 1 HETATM 6145 O O4 . NAG I 2 . ? -67.373 -7.087 34.622 1.00 64.71 ? 908 NAG A O4 1 HETATM 6146 O O5 . NAG I 2 . ? -64.972 -4.461 33.799 1.00 57.66 ? 908 NAG A O5 1 HETATM 6147 O O6 . NAG I 2 . ? -63.938 -7.002 33.460 1.00 47.87 ? 908 NAG A O6 1 HETATM 6148 O O7 . NAG I 2 . ? -67.717 -2.195 30.572 1.00 51.15 ? 908 NAG A O7 1 HETATM 6149 C C1 . NAG J 2 . ? -67.498 -8.352 33.947 1.00 80.08 ? 909 NAG A C1 1 HETATM 6150 C C2 . NAG J 2 . ? -67.799 -9.443 34.967 1.00 87.56 ? 909 NAG A C2 1 HETATM 6151 C C3 . NAG J 2 . ? -67.953 -10.799 34.287 1.00 108.21 ? 909 NAG A C3 1 HETATM 6152 C C4 . NAG J 2 . ? -68.906 -10.709 33.102 1.00 118.41 ? 909 NAG A C4 1 HETATM 6153 C C5 . NAG J 2 . ? -68.540 -9.542 32.193 1.00 116.41 ? 909 NAG A C5 1 HETATM 6154 C C6 . NAG J 2 . ? -69.538 -9.406 31.049 1.00 104.21 ? 909 NAG A C6 1 HETATM 6155 C C7 . NAG J 2 . ? -66.738 -8.704 37.020 1.00 74.37 ? 909 NAG A C7 1 HETATM 6156 C C8 . NAG J 2 . ? -65.470 -8.691 37.820 1.00 72.18 ? 909 NAG A C8 1 HETATM 6157 N N2 . NAG J 2 . ? -66.741 -9.503 35.957 1.00 58.87 ? 909 NAG A N2 1 HETATM 6158 O O3 . NAG J 2 . ? -68.453 -11.752 35.231 1.00 121.31 ? 909 NAG A O3 1 HETATM 6159 O O4 . NAG J 2 . ? -68.855 -11.930 32.354 1.00 129.06 ? 909 NAG A O4 1 HETATM 6160 O O5 . NAG J 2 . ? -68.521 -8.335 32.953 1.00 94.84 ? 909 NAG A O5 1 HETATM 6161 O O6 . NAG J 2 . ? -70.570 -8.486 31.423 1.00 97.46 ? 909 NAG A O6 1 HETATM 6162 O O7 . NAG J 2 . ? -67.705 -8.025 37.325 1.00 86.79 ? 909 NAG A O7 1 HETATM 6163 C C1 . NAG K 2 . ? -66.678 14.982 52.843 1.00 77.11 ? 910 NAG A C1 1 HETATM 6164 C C2 . NAG K 2 . ? -66.734 15.531 54.266 1.00 88.16 ? 910 NAG A C2 1 HETATM 6165 C C3 . NAG K 2 . ? -66.128 16.933 54.311 1.00 92.81 ? 910 NAG A C3 1 HETATM 6166 C C4 . NAG K 2 . ? -64.767 16.900 53.639 1.00 96.22 ? 910 NAG A C4 1 HETATM 6167 C C5 . NAG K 2 . ? -64.826 16.302 52.249 1.00 91.36 ? 910 NAG A C5 1 HETATM 6168 C C6 . NAG K 2 . ? -63.395 16.083 51.810 1.00 92.89 ? 910 NAG A C6 1 HETATM 6169 C C7 . NAG K 2 . ? -69.213 15.850 54.304 1.00 104.69 ? 910 NAG A C7 1 HETATM 6170 C C8 . NAG K 2 . ? -70.485 15.548 55.049 1.00 103.16 ? 910 NAG A C8 1 HETATM 6171 N N2 . NAG K 2 . ? -68.071 15.390 54.859 1.00 89.85 ? 910 NAG A N2 1 HETATM 6172 O O3 . NAG K 2 . ? -65.887 17.339 55.636 1.00 91.06 ? 910 NAG A O3 1 HETATM 6173 O O4 . NAG K 2 . ? -64.224 18.190 53.551 1.00 95.52 ? 910 NAG A O4 1 HETATM 6174 O O5 . NAG K 2 . ? -65.360 15.019 52.385 1.00 87.32 ? 910 NAG A O5 1 HETATM 6175 O O6 . NAG K 2 . ? -62.855 15.130 52.719 1.00 85.24 ? 910 NAG A O6 1 HETATM 6176 O O7 . NAG K 2 . ? -69.284 16.501 53.251 1.00 91.69 ? 910 NAG A O7 1 HETATM 6177 C C1 . NAG L 2 . ? -76.401 18.705 47.138 1.00 111.16 ? 911 NAG A C1 1 HETATM 6178 C C2 . NAG L 2 . ? -75.487 19.923 47.306 1.00 113.83 ? 911 NAG A C2 1 HETATM 6179 C C3 . NAG L 2 . ? -75.534 20.436 48.738 1.00 122.69 ? 911 NAG A C3 1 HETATM 6180 C C4 . NAG L 2 . ? -76.960 20.480 49.300 1.00 129.10 ? 911 NAG A C4 1 HETATM 6181 C C5 . NAG L 2 . ? -77.770 19.233 48.960 1.00 140.32 ? 911 NAG A C5 1 HETATM 6182 C C6 . NAG L 2 . ? -79.216 19.390 49.436 1.00 142.32 ? 911 NAG A C6 1 HETATM 6183 C C7 . NAG L 2 . ? -73.536 20.107 45.800 1.00 111.00 ? 911 NAG A C7 1 HETATM 6184 C C8 . NAG L 2 . ? -72.077 19.803 45.591 1.00 101.82 ? 911 NAG A C8 1 HETATM 6185 N N2 . NAG L 2 . ? -74.090 19.670 46.940 1.00 111.50 ? 911 NAG A N2 1 HETATM 6186 O O3 . NAG L 2 . ? -74.970 21.729 48.744 1.00 115.94 ? 911 NAG A O3 1 HETATM 6187 O O4 . NAG L 2 . ? -76.907 20.563 50.706 1.00 127.85 ? 911 NAG A O4 1 HETATM 6188 O O5 . NAG L 2 . ? -77.718 18.978 47.569 1.00 121.44 ? 911 NAG A O5 1 HETATM 6189 O O6 . NAG L 2 . ? -79.933 20.236 48.563 1.00 145.25 ? 911 NAG A O6 1 HETATM 6190 O O7 . NAG L 2 . ? -74.155 20.732 44.939 1.00 108.50 ? 911 NAG A O7 1 HETATM 6191 C C1 . NAG M 2 . ? -76.843 -2.345 37.004 1.00 45.78 ? 912 NAG A C1 1 HETATM 6192 C C2 . NAG M 2 . ? -76.344 -3.549 36.215 1.00 43.69 ? 912 NAG A C2 1 HETATM 6193 C C3 . NAG M 2 . ? -76.182 -3.241 34.749 1.00 47.27 ? 912 NAG A C3 1 HETATM 6194 C C4 . NAG M 2 . ? -77.500 -2.738 34.225 1.00 45.76 ? 912 NAG A C4 1 HETATM 6195 C C5 . NAG M 2 . ? -77.977 -1.593 35.090 1.00 48.71 ? 912 NAG A C5 1 HETATM 6196 C C6 . NAG M 2 . ? -79.260 -0.987 34.543 1.00 46.80 ? 912 NAG A C6 1 HETATM 6197 C C7 . NAG M 2 . ? -74.778 -5.176 37.059 1.00 46.52 ? 912 NAG A C7 1 HETATM 6198 C C8 . NAG M 2 . ? -73.400 -5.454 37.538 1.00 46.03 ? 912 NAG A C8 1 HETATM 6199 N N2 . NAG M 2 . ? -75.043 -3.939 36.690 1.00 50.29 ? 912 NAG A N2 1 HETATM 6200 O O3 . NAG M 2 . ? -75.620 -4.349 34.033 1.00 45.88 ? 912 NAG A O3 1 HETATM 6201 O O4 . NAG M 2 . ? -77.258 -2.215 32.952 1.00 54.65 ? 912 NAG A O4 1 HETATM 6202 O O5 . NAG M 2 . ? -78.101 -1.976 36.451 1.00 50.60 ? 912 NAG A O5 1 HETATM 6203 O O6 . NAG M 2 . ? -80.221 -2.002 34.487 1.00 45.37 ? 912 NAG A O6 1 HETATM 6204 O O7 . NAG M 2 . ? -75.615 -6.051 37.067 1.00 51.98 ? 912 NAG A O7 1 HETATM 6205 C C1 . NAG N 2 . ? -78.299 -2.637 32.048 1.00 50.66 ? 913 NAG A C1 1 HETATM 6206 C C2 . NAG N 2 . ? -78.203 -1.812 30.785 1.00 52.93 ? 913 NAG A C2 1 HETATM 6207 C C3 . NAG N 2 . ? -79.115 -2.238 29.627 1.00 57.98 ? 913 NAG A C3 1 HETATM 6208 C C4 . NAG N 2 . ? -79.091 -3.764 29.480 1.00 58.33 ? 913 NAG A C4 1 HETATM 6209 C C5 . NAG N 2 . ? -79.214 -4.402 30.874 1.00 62.68 ? 913 NAG A C5 1 HETATM 6210 C C6 . NAG N 2 . ? -79.126 -5.926 30.884 1.00 56.89 ? 913 NAG A C6 1 HETATM 6211 C C7 . NAG N 2 . ? -77.053 0.284 30.878 1.00 49.69 ? 913 NAG A C7 1 HETATM 6212 C C8 . NAG N 2 . ? -77.124 1.771 31.027 1.00 42.88 ? 913 NAG A C8 1 HETATM 6213 N N2 . NAG N 2 . ? -78.214 -0.386 31.013 1.00 43.70 ? 913 NAG A N2 1 HETATM 6214 O O3 . NAG N 2 . ? -78.572 -1.668 28.453 1.00 45.89 ? 913 NAG A O3 1 HETATM 6215 O O4 . NAG N 2 . ? -80.101 -4.207 28.586 1.00 68.06 ? 913 NAG A O4 1 HETATM 6216 O O5 . NAG N 2 . ? -78.102 -3.956 31.631 1.00 56.91 ? 913 NAG A O5 1 HETATM 6217 O O6 . NAG N 2 . ? -77.847 -6.233 30.356 1.00 75.99 ? 913 NAG A O6 1 HETATM 6218 O O7 . NAG N 2 . ? -75.958 -0.284 30.628 1.00 53.38 ? 913 NAG A O7 1 HETATM 6219 C C1 . BMA O 3 . ? -79.573 -4.782 27.365 1.00 68.33 ? 914 BMA A C1 1 HETATM 6220 C C2 . BMA O 3 . ? -80.598 -5.743 26.769 1.00 82.25 ? 914 BMA A C2 1 HETATM 6221 C C3 . BMA O 3 . ? -80.013 -6.431 25.529 1.00 99.38 ? 914 BMA A C3 1 HETATM 6222 C C4 . BMA O 3 . ? -79.615 -5.353 24.540 1.00 97.38 ? 914 BMA A C4 1 HETATM 6223 C C5 . BMA O 3 . ? -78.685 -4.331 25.195 1.00 98.11 ? 914 BMA A C5 1 HETATM 6224 C C6 . BMA O 3 . ? -78.293 -3.214 24.205 1.00 106.67 ? 914 BMA A C6 1 HETATM 6225 O O2 . BMA O 3 . ? -81.739 -4.964 26.425 1.00 83.76 ? 914 BMA A O2 1 HETATM 6226 O O3 . BMA O 3 . ? -80.797 -7.445 24.836 1.00 107.38 ? 914 BMA A O3 1 HETATM 6227 O O4 . BMA O 3 . ? -78.934 -5.984 23.459 1.00 103.82 ? 914 BMA A O4 1 HETATM 6228 O O5 . BMA O 3 . ? -79.306 -3.793 26.377 1.00 83.78 ? 914 BMA A O5 1 HETATM 6229 O O6 . BMA O 3 . ? -79.425 -2.382 23.882 1.00 125.48 ? 914 BMA A O6 1 HETATM 6230 C C1 . MAN P 4 . ? -79.153 -1.414 22.818 1.00 128.10 ? 915 MAN A C1 1 HETATM 6231 C C2 . MAN P 4 . ? -80.198 -0.285 22.862 1.00 119.52 ? 915 MAN A C2 1 HETATM 6232 C C3 . MAN P 4 . ? -81.609 -0.824 22.537 1.00 114.32 ? 915 MAN A C3 1 HETATM 6233 C C4 . MAN P 4 . ? -81.607 -1.630 21.238 1.00 104.70 ? 915 MAN A C4 1 HETATM 6234 C C5 . MAN P 4 . ? -80.450 -2.626 21.292 1.00 103.58 ? 915 MAN A C5 1 HETATM 6235 C C6 . MAN P 4 . ? -80.323 -3.499 20.068 1.00 93.27 ? 915 MAN A C6 1 HETATM 6236 O O2 . MAN P 4 . ? -79.811 0.706 21.938 1.00 97.01 ? 915 MAN A O2 1 HETATM 6237 O O3 . MAN P 4 . ? -82.618 0.169 22.530 1.00 110.89 ? 915 MAN A O3 1 HETATM 6238 O O4 . MAN P 4 . ? -82.811 -2.353 21.172 1.00 88.82 ? 915 MAN A O4 1 HETATM 6239 O O5 . MAN P 4 . ? -79.212 -1.966 21.512 1.00 109.63 ? 915 MAN A O5 1 HETATM 6240 O O6 . MAN P 4 . ? -79.053 -4.102 20.179 1.00 92.88 ? 915 MAN A O6 1 HETATM 6241 C C1 . MAN Q 4 . ? -82.184 -7.592 25.206 1.00 116.42 ? 916 MAN A C1 1 HETATM 6242 C C2 . MAN Q 4 . ? -82.334 -8.619 26.323 1.00 124.11 ? 916 MAN A C2 1 HETATM 6243 C C3 . MAN Q 4 . ? -81.887 -9.993 25.827 1.00 127.31 ? 916 MAN A C3 1 HETATM 6244 C C4 . MAN Q 4 . ? -82.698 -10.391 24.597 1.00 127.02 ? 916 MAN A C4 1 HETATM 6245 C C5 . MAN Q 4 . ? -82.699 -9.271 23.554 1.00 129.71 ? 916 MAN A C5 1 HETATM 6246 C C6 . MAN Q 4 . ? -83.666 -9.614 22.420 1.00 126.32 ? 916 MAN A C6 1 HETATM 6247 O O2 . MAN Q 4 . ? -83.697 -8.671 26.691 1.00 109.41 ? 916 MAN A O2 1 HETATM 6248 O O3 . MAN Q 4 . ? -82.059 -10.953 26.844 1.00 115.74 ? 916 MAN A O3 1 HETATM 6249 O O4 . MAN Q 4 . ? -82.154 -11.569 24.029 1.00 112.61 ? 916 MAN A O4 1 HETATM 6250 O O5 . MAN Q 4 . ? -83.017 -7.998 24.120 1.00 131.61 ? 916 MAN A O5 1 HETATM 6251 O O6 . MAN Q 4 . ? -83.126 -10.668 21.647 1.00 119.51 ? 916 MAN A O6 1 HETATM 6252 C C1 . NAG R 2 . ? -87.106 12.673 33.188 1.00 65.45 ? 917 NAG A C1 1 HETATM 6253 C C2 . NAG R 2 . ? -86.091 13.800 33.108 1.00 64.15 ? 917 NAG A C2 1 HETATM 6254 C C3 . NAG R 2 . ? -86.026 14.247 31.664 1.00 71.02 ? 917 NAG A C3 1 HETATM 6255 C C4 . NAG R 2 . ? -85.574 13.045 30.858 1.00 80.81 ? 917 NAG A C4 1 HETATM 6256 C C5 . NAG R 2 . ? -86.515 11.856 31.093 1.00 81.18 ? 917 NAG A C5 1 HETATM 6257 C C6 . NAG R 2 . ? -86.058 10.624 30.310 1.00 87.35 ? 917 NAG A C6 1 HETATM 6258 C C7 . NAG R 2 . ? -85.728 15.640 34.684 1.00 70.41 ? 917 NAG A C7 1 HETATM 6259 C C8 . NAG R 2 . ? -86.407 16.605 35.613 1.00 67.50 ? 917 NAG A C8 1 HETATM 6260 N N2 . NAG R 2 . ? -86.540 14.836 33.998 1.00 70.61 ? 917 NAG A N2 1 HETATM 6261 O O3 . NAG R 2 . ? -85.088 15.280 31.488 1.00 85.03 ? 917 NAG A O3 1 HETATM 6262 O O4 . NAG R 2 . ? -85.516 13.414 29.504 1.00 85.57 ? 917 NAG A O4 1 HETATM 6263 O O5 . NAG R 2 . ? -86.605 11.561 32.483 1.00 72.59 ? 917 NAG A O5 1 HETATM 6264 O O6 . NAG R 2 . ? -84.661 10.416 30.472 1.00 77.90 ? 917 NAG A O6 1 HETATM 6265 O O7 . NAG R 2 . ? -84.506 15.648 34.568 1.00 72.05 ? 917 NAG A O7 1 HETATM 6266 S S . SO4 S 5 . ? -93.636 -22.059 53.359 1.00 90.28 ? 918 SO4 A S 1 HETATM 6267 O O1 . SO4 S 5 . ? -92.542 -21.717 52.423 1.00 85.84 ? 918 SO4 A O1 1 HETATM 6268 O O2 . SO4 S 5 . ? -94.132 -23.379 52.929 1.00 87.97 ? 918 SO4 A O2 1 HETATM 6269 O O3 . SO4 S 5 . ? -94.708 -21.027 53.308 1.00 71.23 ? 918 SO4 A O3 1 HETATM 6270 O O4 . SO4 S 5 . ? -93.132 -22.147 54.754 1.00 96.14 ? 918 SO4 A O4 1 HETATM 6271 S S . SO4 T 5 . ? -42.063 -11.749 -6.512 1.00 120.97 ? 919 SO4 A S 1 HETATM 6272 O O1 . SO4 T 5 . ? -41.089 -12.700 -7.090 1.00 132.40 ? 919 SO4 A O1 1 HETATM 6273 O O2 . SO4 T 5 . ? -42.977 -11.251 -7.564 1.00 108.98 ? 919 SO4 A O2 1 HETATM 6274 O O3 . SO4 T 5 . ? -42.858 -12.476 -5.495 1.00 136.52 ? 919 SO4 A O3 1 HETATM 6275 O O4 . SO4 T 5 . ? -41.328 -10.608 -5.906 1.00 94.36 ? 919 SO4 A O4 1 HETATM 6276 S S . SO4 U 5 . ? -38.371 5.963 6.471 1.00 112.87 ? 920 SO4 A S 1 HETATM 6277 O O1 . SO4 U 5 . ? -38.144 7.422 6.328 1.00 98.98 ? 920 SO4 A O1 1 HETATM 6278 O O2 . SO4 U 5 . ? -39.214 5.508 5.335 1.00 97.61 ? 920 SO4 A O2 1 HETATM 6279 O O3 . SO4 U 5 . ? -39.050 5.739 7.765 1.00 109.36 ? 920 SO4 A O3 1 HETATM 6280 O O4 . SO4 U 5 . ? -37.091 5.205 6.457 1.00 104.59 ? 920 SO4 A O4 1 HETATM 6281 O O1 . MES V 6 . ? -58.122 1.145 0.956 0.50 58.46 ? 921 MES A O1 1 HETATM 6282 C C2 . MES V 6 . ? -59.484 1.274 0.563 0.50 80.37 ? 921 MES A C2 1 HETATM 6283 C C3 . MES V 6 . ? -60.137 -0.097 0.249 0.50 81.47 ? 921 MES A C3 1 HETATM 6284 N N4 . MES V 6 . ? -59.342 -0.939 -0.689 0.50 82.00 ? 921 MES A N4 1 HETATM 6285 C C5 . MES V 6 . ? -57.905 -0.920 -0.354 0.50 68.13 ? 921 MES A C5 1 HETATM 6286 C C6 . MES V 6 . ? -57.418 0.518 -0.104 0.50 70.59 ? 921 MES A C6 1 HETATM 6287 C C7 . MES V 6 . ? -59.800 -2.352 -0.681 0.50 79.38 ? 921 MES A C7 1 HETATM 6288 C C8 . MES V 6 . ? -61.324 -2.478 -0.731 0.50 74.79 ? 921 MES A C8 1 HETATM 6289 S S . MES V 6 . ? -61.839 -3.441 0.523 0.50 78.70 ? 921 MES A S 1 HETATM 6290 O O1S . MES V 6 . ? -62.672 -4.549 0.021 0.50 79.13 ? 921 MES A O1S 1 HETATM 6291 O O2S . MES V 6 . ? -60.672 -4.005 1.246 0.50 86.40 ? 921 MES A O2S 1 HETATM 6292 O O3S . MES V 6 . ? -62.620 -2.638 1.479 0.50 74.19 ? 921 MES A O3S 1 HETATM 6293 O O . HOH W 7 . ? -53.771 -22.914 -6.899 1.00 80.55 ? 1001 HOH A O 1 HETATM 6294 O O . HOH W 7 . ? -47.799 -0.137 40.618 1.00 57.96 ? 1002 HOH A O 1 HETATM 6295 O O . HOH W 7 . ? -59.191 13.715 45.867 1.00 45.50 ? 1003 HOH A O 1 HETATM 6296 O O . HOH W 7 . ? -85.650 -12.128 48.302 1.00 57.95 ? 1004 HOH A O 1 HETATM 6297 O O . HOH W 7 . ? -89.197 7.476 54.270 1.00 69.96 ? 1005 HOH A O 1 HETATM 6298 O O . HOH W 7 . ? -85.429 -7.558 24.451 1.00 92.62 ? 1006 HOH A O 1 HETATM 6299 O O . HOH W 7 . ? -67.938 17.799 44.846 1.00 65.34 ? 1007 HOH A O 1 HETATM 6300 O O . HOH W 7 . ? -109.626 -9.840 38.143 1.00 92.98 ? 1008 HOH A O 1 HETATM 6301 O O . HOH W 7 . ? -57.726 12.159 42.168 1.00 52.18 ? 1009 HOH A O 1 HETATM 6302 O O . HOH W 7 . ? -40.897 -6.149 21.366 1.00 48.34 ? 1010 HOH A O 1 HETATM 6303 O O . HOH W 7 . ? -61.302 -21.558 10.906 1.00 55.18 ? 1011 HOH A O 1 HETATM 6304 O O . HOH W 7 . ? -55.798 -13.002 20.651 1.00 77.57 ? 1012 HOH A O 1 HETATM 6305 O O . HOH W 7 . ? -47.217 12.148 14.001 1.00 72.04 ? 1013 HOH A O 1 HETATM 6306 O O . HOH W 7 . ? -80.695 -36.219 -1.212 1.00 91.95 ? 1014 HOH A O 1 HETATM 6307 O O . HOH W 7 . ? -80.060 13.014 40.602 1.00 54.26 ? 1015 HOH A O 1 HETATM 6308 O O . HOH W 7 . ? -71.080 2.655 54.350 1.00 67.82 ? 1016 HOH A O 1 HETATM 6309 O O . HOH W 7 . ? -65.559 4.753 23.140 1.00 50.07 ? 1017 HOH A O 1 HETATM 6310 O O . HOH W 7 . ? -60.868 4.101 13.783 1.00 50.59 ? 1018 HOH A O 1 HETATM 6311 O O . HOH W 7 . ? -77.459 -6.178 33.932 1.00 63.53 ? 1019 HOH A O 1 HETATM 6312 O O . HOH W 7 . ? -65.890 11.538 44.551 1.00 49.73 ? 1020 HOH A O 1 HETATM 6313 O O . HOH W 7 . ? -80.009 -7.235 39.733 1.00 66.64 ? 1021 HOH A O 1 HETATM 6314 O O . HOH W 7 . ? -58.515 3.033 8.660 1.00 53.11 ? 1022 HOH A O 1 HETATM 6315 O O . HOH W 7 . ? -54.617 4.978 11.475 1.00 49.46 ? 1023 HOH A O 1 HETATM 6316 O O . HOH W 7 . ? -70.279 -7.295 47.353 1.00 42.23 ? 1024 HOH A O 1 HETATM 6317 O O . HOH W 7 . ? -80.557 -4.329 35.644 1.00 53.45 ? 1025 HOH A O 1 HETATM 6318 O O . HOH W 7 . ? -80.868 0.293 31.528 1.00 59.74 ? 1026 HOH A O 1 HETATM 6319 O O . HOH W 7 . ? -63.792 13.669 31.874 1.00 49.47 ? 1027 HOH A O 1 HETATM 6320 O O . HOH W 7 . ? -81.050 -9.639 49.818 1.00 57.34 ? 1028 HOH A O 1 HETATM 6321 O O . HOH W 7 . ? -87.951 9.201 48.574 1.00 65.57 ? 1029 HOH A O 1 HETATM 6322 O O . HOH W 7 . ? -40.804 -18.817 13.051 1.00 54.43 ? 1030 HOH A O 1 HETATM 6323 O O . HOH W 7 . ? -67.276 -6.564 46.033 1.00 50.90 ? 1031 HOH A O 1 HETATM 6324 O O . HOH W 7 . ? -68.861 -15.258 4.645 1.00 71.36 ? 1032 HOH A O 1 HETATM 6325 O O . HOH W 7 . ? -64.690 -12.283 0.085 1.00 57.91 ? 1033 HOH A O 1 HETATM 6326 O O . HOH W 7 . ? -48.490 -9.956 23.513 1.00 48.46 ? 1034 HOH A O 1 HETATM 6327 O O . HOH W 7 . ? -63.780 -39.706 -4.447 1.00 78.98 ? 1035 HOH A O 1 HETATM 6328 O O . HOH W 7 . ? -56.037 -13.406 -3.466 1.00 61.22 ? 1036 HOH A O 1 HETATM 6329 O O . HOH W 7 . ? -41.439 1.006 22.352 1.00 50.98 ? 1037 HOH A O 1 HETATM 6330 O O . HOH W 7 . ? -60.092 -30.797 -5.032 1.00 69.66 ? 1038 HOH A O 1 HETATM 6331 O O . HOH W 7 . ? -69.733 14.078 35.075 1.00 50.96 ? 1039 HOH A O 1 HETATM 6332 O O . HOH W 7 . ? -75.717 14.415 36.154 1.00 60.44 ? 1040 HOH A O 1 HETATM 6333 O O . HOH W 7 . ? -56.432 12.724 39.711 1.00 67.11 ? 1041 HOH A O 1 HETATM 6334 O O . HOH W 7 . ? -53.099 -28.638 14.265 1.00 62.73 ? 1042 HOH A O 1 HETATM 6335 O O . HOH W 7 . ? -59.193 -17.958 -5.727 1.00 58.45 ? 1043 HOH A O 1 HETATM 6336 O O . HOH W 7 . ? -46.510 -24.559 23.233 1.00 70.79 ? 1044 HOH A O 1 HETATM 6337 O O . HOH W 7 . ? -53.984 -8.064 -0.632 1.00 47.05 ? 1045 HOH A O 1 HETATM 6338 O O . HOH W 7 . ? -52.218 0.224 8.314 1.00 47.03 ? 1046 HOH A O 1 HETATM 6339 O O . HOH W 7 . ? -68.290 8.045 50.134 1.00 55.37 ? 1047 HOH A O 1 HETATM 6340 O O . HOH W 7 . ? -36.726 4.831 32.065 1.00 82.34 ? 1048 HOH A O 1 HETATM 6341 O O . HOH W 7 . ? -48.939 11.550 33.410 1.00 75.28 ? 1049 HOH A O 1 HETATM 6342 O O . HOH W 7 . ? -66.762 5.661 48.901 1.00 58.44 ? 1050 HOH A O 1 HETATM 6343 O O . HOH W 7 . ? -108.263 2.396 36.849 1.00 89.29 ? 1051 HOH A O 1 HETATM 6344 O O . HOH W 7 . ? -78.116 -5.359 38.304 1.00 67.81 ? 1052 HOH A O 1 HETATM 6345 O O . HOH W 7 . ? -91.135 4.695 48.702 1.00 67.38 ? 1053 HOH A O 1 HETATM 6346 O O . HOH W 7 . ? -63.181 -5.294 31.187 1.00 56.43 ? 1054 HOH A O 1 HETATM 6347 O O . HOH W 7 . ? -52.224 12.458 13.400 1.00 67.79 ? 1055 HOH A O 1 HETATM 6348 O O . HOH W 7 . ? -68.404 -1.773 50.938 1.00 48.09 ? 1056 HOH A O 1 HETATM 6349 O O . HOH W 7 . ? -49.506 2.887 39.329 1.00 55.45 ? 1057 HOH A O 1 HETATM 6350 O O . HOH W 7 . ? -47.954 -11.633 -1.375 1.00 54.26 ? 1058 HOH A O 1 HETATM 6351 O O . HOH W 7 . ? -55.689 5.862 6.797 1.00 51.45 ? 1059 HOH A O 1 HETATM 6352 O O . HOH W 7 . ? -59.620 -21.990 19.020 1.00 76.85 ? 1060 HOH A O 1 HETATM 6353 O O . HOH W 7 . ? -61.235 6.899 12.258 1.00 68.16 ? 1061 HOH A O 1 HETATM 6354 O O . HOH W 7 . ? -43.214 7.064 9.396 1.00 61.04 ? 1062 HOH A O 1 HETATM 6355 O O . HOH W 7 . ? -42.687 -19.866 8.414 1.00 60.20 ? 1063 HOH A O 1 HETATM 6356 O O . HOH W 7 . ? -69.013 -25.110 -7.169 1.00 70.82 ? 1064 HOH A O 1 HETATM 6357 O O . HOH W 7 . ? -60.784 8.725 50.365 1.00 67.72 ? 1065 HOH A O 1 HETATM 6358 O O . HOH W 7 . ? -68.012 -5.397 48.917 1.00 43.47 ? 1066 HOH A O 1 HETATM 6359 O O . HOH W 7 . ? -60.858 -5.122 16.799 1.00 56.12 ? 1067 HOH A O 1 HETATM 6360 O O . HOH W 7 . ? -62.508 11.789 4.718 1.00 54.30 ? 1068 HOH A O 1 HETATM 6361 O O . HOH W 7 . ? -83.042 -4.575 36.853 1.00 58.12 ? 1069 HOH A O 1 HETATM 6362 O O . HOH W 7 . ? -87.206 -15.163 38.306 1.00 79.96 ? 1070 HOH A O 1 HETATM 6363 O O . HOH W 7 . ? -82.760 -18.697 -7.017 1.00 81.84 ? 1071 HOH A O 1 HETATM 6364 O O . HOH W 7 . ? -47.471 16.146 34.549 1.00 81.23 ? 1072 HOH A O 1 HETATM 6365 O O . HOH W 7 . ? -92.659 -22.606 46.241 1.00 72.18 ? 1073 HOH A O 1 HETATM 6366 O O . HOH W 7 . ? -54.817 -29.206 16.431 1.00 70.09 ? 1074 HOH A O 1 HETATM 6367 O O . HOH W 7 . ? -72.583 -4.479 33.248 1.00 73.40 ? 1075 HOH A O 1 HETATM 6368 O O . HOH W 7 . ? -79.635 14.152 28.739 1.00 82.77 ? 1076 HOH A O 1 HETATM 6369 O O . HOH W 7 . ? -60.771 6.867 52.591 1.00 57.63 ? 1077 HOH A O 1 HETATM 6370 O O . HOH W 7 . ? -75.048 12.607 26.486 1.00 63.82 ? 1078 HOH A O 1 HETATM 6371 O O . HOH W 7 . ? -66.318 3.336 20.683 1.00 66.25 ? 1079 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLU 1 27 ? ? ? A . n A 1 2 GLU 2 28 ? ? ? A . n A 1 3 ASN 3 29 ? ? ? A . n A 1 4 PHE 4 30 ? ? ? A . n A 1 5 SER 5 31 ? ? ? A . n A 1 6 ARG 6 32 ? ? ? A . n A 1 7 SER 7 33 33 SER SER A . n A 1 8 TYR 8 34 34 TYR TYR A . n A 1 9 PRO 9 35 35 PRO PRO A . n A 1 10 CYS 10 36 36 CYS CYS A . n A 1 11 ASP 11 37 37 ASP ASP A . n A 1 12 GLU 12 38 38 GLU GLU A . n A 1 13 LYS 13 39 39 LYS LYS A . n A 1 14 LYS 14 40 40 LYS LYS A . n A 1 15 GLN 15 41 41 GLN GLN A . n A 1 16 ASN 16 42 42 ASN ASN A . n A 1 17 ASP 17 43 43 ASP ASP A . n A 1 18 SER 18 44 44 SER SER A . n A 1 19 VAL 19 45 45 VAL VAL A . n A 1 20 ILE 20 46 46 ILE ILE A . n A 1 21 ALA 21 47 47 ALA ALA A . n A 1 22 GLU 22 48 48 GLU GLU A . n A 1 23 CYS 23 49 49 CYS CYS A . n A 1 24 SER 24 50 50 SER SER A . n A 1 25 ASN 25 51 51 ASN ASN A . n A 1 26 ARG 26 52 52 ARG ARG A . n A 1 27 ARG 27 53 53 ARG ARG A . n A 1 28 LEU 28 54 54 LEU LEU A . n A 1 29 GLN 29 55 55 GLN GLN A . n A 1 30 GLU 30 56 56 GLU GLU A . n A 1 31 VAL 31 57 57 VAL VAL A . n A 1 32 PRO 32 58 58 PRO PRO A . n A 1 33 GLN 33 59 59 GLN GLN A . n A 1 34 THR 34 60 60 THR THR A . n A 1 35 VAL 35 61 61 VAL VAL A . n A 1 36 GLY 36 62 62 GLY GLY A . n A 1 37 LYS 37 63 63 LYS LYS A . n A 1 38 TYR 38 64 64 TYR TYR A . n A 1 39 VAL 39 65 65 VAL VAL A . n A 1 40 THR 40 66 66 THR THR A . n A 1 41 GLU 41 67 67 GLU GLU A . n A 1 42 LEU 42 68 68 LEU LEU A . n A 1 43 ASP 43 69 69 ASP ASP A . n A 1 44 LEU 44 70 70 LEU LEU A . n A 1 45 SER 45 71 71 SER SER A . n A 1 46 ASP 46 72 72 ASP ASP A . n A 1 47 ASN 47 73 73 ASN ASN A . n A 1 48 PHE 48 74 74 PHE PHE A . n A 1 49 ILE 49 75 75 ILE ILE A . n A 1 50 THR 50 76 76 THR THR A . n A 1 51 HIS 51 77 77 HIS HIS A . n A 1 52 ILE 52 78 78 ILE ILE A . n A 1 53 THR 53 79 79 THR THR A . n A 1 54 ASN 54 80 80 ASN ASN A . n A 1 55 GLU 55 81 81 GLU GLU A . n A 1 56 SER 56 82 82 SER SER A . n A 1 57 PHE 57 83 83 PHE PHE A . n A 1 58 GLN 58 84 84 GLN GLN A . n A 1 59 GLY 59 85 85 GLY GLY A . n A 1 60 LEU 60 86 86 LEU LEU A . n A 1 61 GLN 61 87 87 GLN GLN A . n A 1 62 ASN 62 88 88 ASN ASN A . n A 1 63 LEU 63 89 89 LEU LEU A . n A 1 64 THR 64 90 90 THR THR A . n A 1 65 LYS 65 91 91 LYS LYS A . n A 1 66 ILE 66 92 92 ILE ILE A . n A 1 67 ASN 67 93 93 ASN ASN A . n A 1 68 LEU 68 94 94 LEU LEU A . n A 1 69 ASN 69 95 95 ASN ASN A . n A 1 70 HIS 70 96 96 HIS HIS A . n A 1 71 ASN 71 97 97 ASN ASN A . n A 1 72 PRO 72 98 98 PRO PRO A . n A 1 73 ASN 73 99 99 ASN ASN A . n A 1 74 VAL 74 100 100 VAL VAL A . n A 1 75 GLN 75 101 ? ? ? A . n A 1 76 HIS 76 102 ? ? ? A . n A 1 77 GLN 77 103 ? ? ? A . n A 1 78 ASN 78 104 ? ? ? A . n A 1 79 GLY 79 105 ? ? ? A . n A 1 80 ASN 80 106 ? ? ? A . n A 1 81 PRO 81 107 ? ? ? A . n A 1 82 GLY 82 108 ? ? ? A . n A 1 83 ILE 83 109 ? ? ? A . n A 1 84 GLN 84 110 ? ? ? A . n A 1 85 SER 85 111 ? ? ? A . n A 1 86 ASN 86 112 ? ? ? A . n A 1 87 GLY 87 113 113 GLY GLY A . n A 1 88 LEU 88 114 114 LEU LEU A . n A 1 89 ASN 89 115 115 ASN ASN A . n A 1 90 ILE 90 116 116 ILE ILE A . n A 1 91 THR 91 117 117 THR THR A . n A 1 92 ASP 92 118 118 ASP ASP A . n A 1 93 GLY 93 119 119 GLY GLY A . n A 1 94 ALA 94 120 120 ALA ALA A . n A 1 95 PHE 95 121 121 PHE PHE A . n A 1 96 LEU 96 122 122 LEU LEU A . n A 1 97 ASN 97 123 123 ASN ASN A . n A 1 98 LEU 98 124 124 LEU LEU A . n A 1 99 LYS 99 125 125 LYS LYS A . n A 1 100 ASN 100 126 126 ASN ASN A . n A 1 101 LEU 101 127 127 LEU LEU A . n A 1 102 ARG 102 128 128 ARG ARG A . n A 1 103 GLU 103 129 129 GLU GLU A . n A 1 104 LEU 104 130 130 LEU LEU A . n A 1 105 LEU 105 131 131 LEU LEU A . n A 1 106 LEU 106 132 132 LEU LEU A . n A 1 107 GLU 107 133 133 GLU GLU A . n A 1 108 ASP 108 134 134 ASP ASP A . n A 1 109 ASN 109 135 135 ASN ASN A . n A 1 110 GLN 110 136 136 GLN GLN A . n A 1 111 LEU 111 137 137 LEU LEU A . n A 1 112 PRO 112 138 138 PRO PRO A . n A 1 113 GLN 113 139 139 GLN GLN A . n A 1 114 ILE 114 140 140 ILE ILE A . n A 1 115 PRO 115 141 141 PRO PRO A . n A 1 116 SER 116 142 142 SER SER A . n A 1 117 GLY 117 143 143 GLY GLY A . n A 1 118 LEU 118 144 144 LEU LEU A . n A 1 119 PRO 119 145 145 PRO PRO A . n A 1 120 GLU 120 146 146 GLU GLU A . n A 1 121 SER 121 147 147 SER SER A . n A 1 122 LEU 122 148 148 LEU LEU A . n A 1 123 THR 123 149 149 THR THR A . n A 1 124 GLU 124 150 150 GLU GLU A . n A 1 125 LEU 125 151 151 LEU LEU A . n A 1 126 SER 126 152 152 SER SER A . n A 1 127 LEU 127 153 153 LEU LEU A . n A 1 128 ILE 128 154 154 ILE ILE A . n A 1 129 GLN 129 155 155 GLN GLN A . n A 1 130 ASN 130 156 156 ASN ASN A . n A 1 131 ASN 131 157 157 ASN ASN A . n A 1 132 ILE 132 158 158 ILE ILE A . n A 1 133 TYR 133 159 159 TYR TYR A . n A 1 134 ASN 134 160 160 ASN ASN A . n A 1 135 ILE 135 161 161 ILE ILE A . n A 1 136 THR 136 162 162 THR THR A . n A 1 137 LYS 137 163 163 LYS LYS A . n A 1 138 GLU 138 164 164 GLU GLU A . n A 1 139 GLY 139 165 165 GLY GLY A . n A 1 140 ILE 140 166 166 ILE ILE A . n A 1 141 SER 141 167 167 SER SER A . n A 1 142 ARG 142 168 168 ARG ARG A . n A 1 143 LEU 143 169 169 LEU LEU A . n A 1 144 ILE 144 170 170 ILE ILE A . n A 1 145 ASN 145 171 171 ASN ASN A . n A 1 146 LEU 146 172 172 LEU LEU A . n A 1 147 LYS 147 173 173 LYS LYS A . n A 1 148 ASN 148 174 174 ASN ASN A . n A 1 149 LEU 149 175 175 LEU LEU A . n A 1 150 TYR 150 176 176 TYR TYR A . n A 1 151 LEU 151 177 177 LEU LEU A . n A 1 152 ALA 152 178 178 ALA ALA A . n A 1 153 TRP 153 179 179 TRP TRP A . n A 1 154 ASN 154 180 180 ASN ASN A . n A 1 155 CYS 155 181 181 CYS CYS A . n A 1 156 TYR 156 182 182 TYR TYR A . n A 1 157 PHE 157 183 183 PHE PHE A . n A 1 158 ASN 158 184 184 ASN ASN A . n A 1 159 LYS 159 185 185 LYS LYS A . n A 1 160 VAL 160 186 186 VAL VAL A . n A 1 161 CYS 161 187 187 CYS CYS A . n A 1 162 GLU 162 188 188 GLU GLU A . n A 1 163 LYS 163 189 189 LYS LYS A . n A 1 164 THR 164 190 190 THR THR A . n A 1 165 ASN 165 191 191 ASN ASN A . n A 1 166 ILE 166 192 192 ILE ILE A . n A 1 167 GLU 167 193 193 GLU GLU A . n A 1 168 ASP 168 194 194 ASP ASP A . n A 1 169 GLY 169 195 195 GLY GLY A . n A 1 170 VAL 170 196 196 VAL VAL A . n A 1 171 PHE 171 197 197 PHE PHE A . n A 1 172 GLU 172 198 198 GLU GLU A . n A 1 173 THR 173 199 199 THR THR A . n A 1 174 LEU 174 200 200 LEU LEU A . n A 1 175 THR 175 201 201 THR THR A . n A 1 176 ASN 176 202 202 ASN ASN A . n A 1 177 LEU 177 203 203 LEU LEU A . n A 1 178 GLU 178 204 204 GLU GLU A . n A 1 179 LEU 179 205 205 LEU LEU A . n A 1 180 LEU 180 206 206 LEU LEU A . n A 1 181 SER 181 207 207 SER SER A . n A 1 182 LEU 182 208 208 LEU LEU A . n A 1 183 SER 183 209 209 SER SER A . n A 1 184 PHE 184 210 210 PHE PHE A . n A 1 185 ASN 185 211 211 ASN ASN A . n A 1 186 SER 186 212 212 SER SER A . n A 1 187 LEU 187 213 213 LEU LEU A . n A 1 188 SER 188 214 214 SER SER A . n A 1 189 HIS 189 215 215 HIS HIS A . n A 1 190 VAL 190 216 216 VAL VAL A . n A 1 191 PRO 191 217 217 PRO PRO A . n A 1 192 PRO 192 218 218 PRO PRO A . n A 1 193 LYS 193 219 219 LYS LYS A . n A 1 194 LEU 194 220 220 LEU LEU A . n A 1 195 PRO 195 221 221 PRO PRO A . n A 1 196 SER 196 222 222 SER SER A . n A 1 197 SER 197 223 223 SER SER A . n A 1 198 LEU 198 224 224 LEU LEU A . n A 1 199 ARG 199 225 225 ARG ARG A . n A 1 200 LYS 200 226 226 LYS LYS A . n A 1 201 LEU 201 227 227 LEU LEU A . n A 1 202 PHE 202 228 228 PHE PHE A . n A 1 203 LEU 203 229 229 LEU LEU A . n A 1 204 SER 204 230 230 SER SER A . n A 1 205 ASN 205 231 231 ASN ASN A . n A 1 206 THR 206 232 232 THR THR A . n A 1 207 GLN 207 233 233 GLN GLN A . n A 1 208 ILE 208 234 234 ILE ILE A . n A 1 209 LYS 209 235 235 LYS LYS A . n A 1 210 TYR 210 236 236 TYR TYR A . n A 1 211 ILE 211 237 237 ILE ILE A . n A 1 212 SER 212 238 238 SER SER A . n A 1 213 GLU 213 239 239 GLU GLU A . n A 1 214 GLU 214 240 240 GLU GLU A . n A 1 215 ASP 215 241 241 ASP ASP A . n A 1 216 PHE 216 242 242 PHE PHE A . n A 1 217 LYS 217 243 243 LYS LYS A . n A 1 218 GLY 218 244 244 GLY GLY A . n A 1 219 LEU 219 245 245 LEU LEU A . n A 1 220 ILE 220 246 246 ILE ILE A . n A 1 221 ASN 221 247 247 ASN ASN A . n A 1 222 LEU 222 248 248 LEU LEU A . n A 1 223 THR 223 249 249 THR THR A . n A 1 224 LEU 224 250 250 LEU LEU A . n A 1 225 LEU 225 251 251 LEU LEU A . n A 1 226 ASP 226 252 252 ASP ASP A . n A 1 227 LEU 227 253 253 LEU LEU A . n A 1 228 SER 228 254 254 SER SER A . n A 1 229 GLY 229 255 255 GLY GLY A . n A 1 230 ASN 230 256 256 ASN ASN A . n A 1 231 CYS 231 257 257 CYS CYS A . n A 1 232 PRO 232 258 258 PRO PRO A . n A 1 233 ARG 233 259 259 ARG ARG A . n A 1 234 CYS 234 260 260 CYS CYS A . n A 1 235 PHE 235 261 261 PHE PHE A . n A 1 236 ASN 236 262 262 ASN ASN A . n A 1 237 ALA 237 263 263 ALA ALA A . n A 1 238 PRO 238 264 264 PRO PRO A . n A 1 239 PHE 239 265 265 PHE PHE A . n A 1 240 PRO 240 266 266 PRO PRO A . n A 1 241 CYS 241 267 267 CYS CYS A . n A 1 242 VAL 242 268 268 VAL VAL A . n A 1 243 PRO 243 269 269 PRO PRO A . n A 1 244 CYS 244 270 270 CYS CYS A . n A 1 245 ASP 245 271 271 ASP ASP A . n A 1 246 GLY 246 272 272 GLY GLY A . n A 1 247 GLY 247 273 273 GLY GLY A . n A 1 248 ALA 248 274 274 ALA ALA A . n A 1 249 SER 249 275 275 SER SER A . n A 1 250 ILE 250 276 276 ILE ILE A . n A 1 251 ASN 251 277 277 ASN ASN A . n A 1 252 ILE 252 278 278 ILE ILE A . n A 1 253 ASP 253 279 279 ASP ASP A . n A 1 254 ARG 254 280 280 ARG ARG A . n A 1 255 PHE 255 281 281 PHE PHE A . n A 1 256 ALA 256 282 282 ALA ALA A . n A 1 257 PHE 257 283 283 PHE PHE A . n A 1 258 GLN 258 284 284 GLN GLN A . n A 1 259 ASN 259 285 285 ASN ASN A . n A 1 260 LEU 260 286 286 LEU LEU A . n A 1 261 THR 261 287 287 THR THR A . n A 1 262 GLN 262 288 288 GLN GLN A . n A 1 263 LEU 263 289 289 LEU LEU A . n A 1 264 ARG 264 290 290 ARG ARG A . n A 1 265 TYR 265 291 291 TYR TYR A . n A 1 266 LEU 266 292 292 LEU LEU A . n A 1 267 ASN 267 293 293 ASN ASN A . n A 1 268 LEU 268 294 294 LEU LEU A . n A 1 269 SER 269 295 295 SER SER A . n A 1 270 SER 270 296 296 SER SER A . n A 1 271 THR 271 297 297 THR THR A . n A 1 272 SER 272 298 298 SER SER A . n A 1 273 LEU 273 299 299 LEU LEU A . n A 1 274 ARG 274 300 300 ARG ARG A . n A 1 275 LYS 275 301 301 LYS LYS A . n A 1 276 ILE 276 302 302 ILE ILE A . n A 1 277 ASN 277 303 303 ASN ASN A . n A 1 278 ALA 278 304 304 ALA ALA A . n A 1 279 ALA 279 305 305 ALA ALA A . n A 1 280 TRP 280 306 306 TRP TRP A . n A 1 281 PHE 281 307 307 PHE PHE A . n A 1 282 LYS 282 308 308 LYS LYS A . n A 1 283 ASN 283 309 309 ASN ASN A . n A 1 284 MET 284 310 310 MET MET A . n A 1 285 PRO 285 311 311 PRO PRO A . n A 1 286 HIS 286 312 312 HIS HIS A . n A 1 287 LEU 287 313 313 LEU LEU A . n A 1 288 LYS 288 314 314 LYS LYS A . n A 1 289 VAL 289 315 315 VAL VAL A . n A 1 290 LEU 290 316 316 LEU LEU A . n A 1 291 ASP 291 317 317 ASP ASP A . n A 1 292 LEU 292 318 318 LEU LEU A . n A 1 293 GLU 293 319 319 GLU GLU A . n A 1 294 PHE 294 320 320 PHE PHE A . n A 1 295 ASN 295 321 321 ASN ASN A . n A 1 296 TYR 296 322 322 TYR TYR A . n A 1 297 LEU 297 323 323 LEU LEU A . n A 1 298 VAL 298 324 324 VAL VAL A . n A 1 299 GLY 299 325 325 GLY GLY A . n A 1 300 GLU 300 326 326 GLU GLU A . n A 1 301 ILE 301 327 327 ILE ILE A . n A 1 302 ALA 302 328 328 ALA ALA A . n A 1 303 SER 303 329 329 SER SER A . n A 1 304 GLY 304 330 330 GLY GLY A . n A 1 305 ALA 305 331 331 ALA ALA A . n A 1 306 PHE 306 332 332 PHE PHE A . n A 1 307 LEU 307 333 333 LEU LEU A . n A 1 308 THR 308 334 334 THR THR A . n A 1 309 MET 309 335 335 MET MET A . n A 1 310 LEU 310 336 336 LEU LEU A . n A 1 311 PRO 311 337 337 PRO PRO A . n A 1 312 ARG 312 338 338 ARG ARG A . n A 1 313 LEU 313 339 339 LEU LEU A . n A 1 314 GLU 314 340 340 GLU GLU A . n A 1 315 ILE 315 341 341 ILE ILE A . n A 1 316 LEU 316 342 342 LEU LEU A . n A 1 317 ASP 317 343 343 ASP ASP A . n A 1 318 LEU 318 344 344 LEU LEU A . n A 1 319 SER 319 345 345 SER SER A . n A 1 320 PHE 320 346 346 PHE PHE A . n A 1 321 ASN 321 347 347 ASN ASN A . n A 1 322 TYR 322 348 348 TYR TYR A . n A 1 323 ILE 323 349 349 ILE ILE A . n A 1 324 LYS 324 350 350 LYS LYS A . n A 1 325 GLY 325 351 351 GLY GLY A . n A 1 326 SER 326 352 352 SER SER A . n A 1 327 TYR 327 353 353 TYR TYR A . n A 1 328 PRO 328 354 354 PRO PRO A . n A 1 329 GLN 329 355 355 GLN GLN A . n A 1 330 HIS 330 356 356 HIS HIS A . n A 1 331 ILE 331 357 357 ILE ILE A . n A 1 332 ASN 332 358 358 ASN ASN A . n A 1 333 ILE 333 359 359 ILE ILE A . n A 1 334 SER 334 360 360 SER SER A . n A 1 335 ARG 335 361 361 ARG ARG A . n A 1 336 ASN 336 362 362 ASN ASN A . n A 1 337 PHE 337 363 363 PHE PHE A . n A 1 338 SER 338 364 364 SER SER A . n A 1 339 LYS 339 365 365 LYS LYS A . n A 1 340 LEU 340 366 366 LEU LEU A . n A 1 341 LEU 341 367 367 LEU LEU A . n A 1 342 SER 342 368 368 SER SER A . n A 1 343 LEU 343 369 369 LEU LEU A . n A 1 344 ARG 344 370 370 ARG ARG A . n A 1 345 ALA 345 371 371 ALA ALA A . n A 1 346 LEU 346 372 372 LEU LEU A . n A 1 347 HIS 347 373 373 HIS HIS A . n A 1 348 LEU 348 374 374 LEU LEU A . n A 1 349 ARG 349 375 375 ARG ARG A . n A 1 350 GLY 350 376 376 GLY GLY A . n A 1 351 TYR 351 377 377 TYR TYR A . n A 1 352 VAL 352 378 378 VAL VAL A . n A 1 353 PHE 353 379 379 PHE PHE A . n A 1 354 GLN 354 380 380 GLN GLN A . n A 1 355 GLU 355 381 381 GLU GLU A . n A 1 356 LEU 356 382 382 LEU LEU A . n A 1 357 ARG 357 383 383 ARG ARG A . n A 1 358 GLU 358 384 384 GLU GLU A . n A 1 359 ASP 359 385 385 ASP ASP A . n A 1 360 ASP 360 386 386 ASP ASP A . n A 1 361 PHE 361 387 387 PHE PHE A . n A 1 362 GLN 362 388 388 GLN GLN A . n A 1 363 PRO 363 389 389 PRO PRO A . n A 1 364 LEU 364 390 390 LEU LEU A . n A 1 365 MET 365 391 391 MET MET A . n A 1 366 GLN 366 392 392 GLN GLN A . n A 1 367 LEU 367 393 393 LEU LEU A . n A 1 368 PRO 368 394 394 PRO PRO A . n A 1 369 ASN 369 395 395 ASN ASN A . n A 1 370 LEU 370 396 396 LEU LEU A . n A 1 371 SER 371 397 397 SER SER A . n A 1 372 THR 372 398 398 THR THR A . n A 1 373 ILE 373 399 399 ILE ILE A . n A 1 374 ASN 374 400 400 ASN ASN A . n A 1 375 LEU 375 401 401 LEU LEU A . n A 1 376 GLY 376 402 402 GLY GLY A . n A 1 377 ILE 377 403 403 ILE ILE A . n A 1 378 ASN 378 404 404 ASN ASN A . n A 1 379 PHE 379 405 405 PHE PHE A . n A 1 380 ILE 380 406 406 ILE ILE A . n A 1 381 LYS 381 407 407 LYS LYS A . n A 1 382 GLN 382 408 408 GLN GLN A . n A 1 383 ILE 383 409 409 ILE ILE A . n A 1 384 ASP 384 410 410 ASP ASP A . n A 1 385 PHE 385 411 411 PHE PHE A . n A 1 386 LYS 386 412 412 LYS LYS A . n A 1 387 LEU 387 413 413 LEU LEU A . n A 1 388 PHE 388 414 414 PHE PHE A . n A 1 389 GLN 389 415 415 GLN GLN A . n A 1 390 ASN 390 416 416 ASN ASN A . n A 1 391 PHE 391 417 417 PHE PHE A . n A 1 392 SER 392 418 418 SER SER A . n A 1 393 ASN 393 419 419 ASN ASN A . n A 1 394 LEU 394 420 420 LEU LEU A . n A 1 395 GLU 395 421 421 GLU GLU A . n A 1 396 ILE 396 422 422 ILE ILE A . n A 1 397 ILE 397 423 423 ILE ILE A . n A 1 398 TYR 398 424 424 TYR TYR A . n A 1 399 LEU 399 425 425 LEU LEU A . n A 1 400 SER 400 426 426 SER SER A . n A 1 401 GLU 401 427 427 GLU GLU A . n A 1 402 ASN 402 428 428 ASN ASN A . n A 1 403 ARG 403 429 429 ARG ARG A . n A 1 404 ILE 404 430 430 ILE ILE A . n A 1 405 SER 405 431 431 SER SER A . n A 1 406 PRO 406 432 432 PRO PRO A . n A 1 407 LEU 407 433 433 LEU LEU A . n A 1 408 VAL 408 434 434 VAL VAL A . n A 1 409 LYS 409 435 ? ? ? A . n A 1 410 ASP 410 436 ? ? ? A . n A 1 411 THR 411 437 ? ? ? A . n A 1 412 ARG 412 438 ? ? ? A . n A 1 413 GLN 413 439 ? ? ? A . n A 1 414 SER 414 440 ? ? ? A . n A 1 415 TYR 415 441 ? ? ? A . n A 1 416 ALA 416 442 ? ? ? A . n A 1 417 ASN 417 443 443 ASN ASN A . n A 1 418 SER 418 444 444 SER SER A . n A 1 419 SER 419 445 445 SER SER A . n A 1 420 SER 420 446 446 SER SER A . n A 1 421 PHE 421 447 447 PHE PHE A . n A 1 422 GLN 422 448 448 GLN GLN A . n A 1 423 ARG 423 449 449 ARG ARG A . n A 1 424 HIS 424 450 450 HIS HIS A . n A 1 425 ILE 425 451 451 ILE ILE A . n A 1 426 ASN 426 452 ? ? ? A . n A 1 427 GLN 427 453 ? ? ? A . n A 1 428 SER 428 454 ? ? ? A . n A 1 429 ASN 429 455 ? ? ? A . n A 1 430 SER 430 456 ? ? ? A . n A 1 431 THR 431 457 ? ? ? A . n A 1 432 ASP 432 458 ? ? ? A . n A 1 433 PHE 433 459 ? ? ? A . n A 1 434 GLU 434 460 ? ? ? A . n A 1 435 PHE 435 461 ? ? ? A . n A 1 436 ASP 436 462 ? ? ? A . n A 1 437 PRO 437 463 463 PRO PRO A . n A 1 438 HIS 438 464 464 HIS HIS A . n A 1 439 SER 439 465 465 SER SER A . n A 1 440 ASN 440 466 466 ASN ASN A . n A 1 441 PHE 441 467 467 PHE PHE A . n A 1 442 TYR 442 468 468 TYR TYR A . n A 1 443 HIS 443 469 469 HIS HIS A . n A 1 444 PHE 444 470 470 PHE PHE A . n A 1 445 THR 445 471 471 THR THR A . n A 1 446 ARG 446 472 472 ARG ARG A . n A 1 447 PRO 447 473 473 PRO PRO A . n A 1 448 LEU 448 474 474 LEU LEU A . n A 1 449 ILE 449 475 475 ILE ILE A . n A 1 450 LYS 450 476 476 LYS LYS A . n A 1 451 PRO 451 477 477 PRO PRO A . n A 1 452 GLN 452 478 478 GLN GLN A . n A 1 453 CYS 453 479 479 CYS CYS A . n A 1 454 ALA 454 480 480 ALA ALA A . n A 1 455 ALA 455 481 481 ALA ALA A . n A 1 456 TYR 456 482 482 TYR TYR A . n A 1 457 GLY 457 483 483 GLY GLY A . n A 1 458 LYS 458 484 484 LYS LYS A . n A 1 459 ALA 459 485 485 ALA ALA A . n A 1 460 LEU 460 486 486 LEU LEU A . n A 1 461 ASP 461 487 487 ASP ASP A . n A 1 462 LEU 462 488 488 LEU LEU A . n A 1 463 SER 463 489 489 SER SER A . n A 1 464 LEU 464 490 490 LEU LEU A . n A 1 465 ASN 465 491 491 ASN ASN A . n A 1 466 SER 466 492 492 SER SER A . n A 1 467 ILE 467 493 493 ILE ILE A . n A 1 468 PHE 468 494 494 PHE PHE A . n A 1 469 PHE 469 495 495 PHE PHE A . n A 1 470 ILE 470 496 496 ILE ILE A . n A 1 471 GLY 471 497 497 GLY GLY A . n A 1 472 PRO 472 498 498 PRO PRO A . n A 1 473 ASN 473 499 499 ASN ASN A . n A 1 474 GLN 474 500 500 GLN GLN A . n A 1 475 PHE 475 501 501 PHE PHE A . n A 1 476 GLU 476 502 502 GLU GLU A . n A 1 477 ASN 477 503 503 ASN ASN A . n A 1 478 LEU 478 504 504 LEU LEU A . n A 1 479 PRO 479 505 505 PRO PRO A . n A 1 480 ASP 480 506 506 ASP ASP A . n A 1 481 ILE 481 507 507 ILE ILE A . n A 1 482 ALA 482 508 508 ALA ALA A . n A 1 483 CYS 483 509 509 CYS CYS A . n A 1 484 LEU 484 510 510 LEU LEU A . n A 1 485 ASN 485 511 511 ASN ASN A . n A 1 486 LEU 486 512 512 LEU LEU A . n A 1 487 SER 487 513 513 SER SER A . n A 1 488 ALA 488 514 514 ALA ALA A . n A 1 489 ASN 489 515 515 ASN ASN A . n A 1 490 SER 490 516 516 SER SER A . n A 1 491 ASN 491 517 517 ASN ASN A . n A 1 492 ALA 492 518 518 ALA ALA A . n A 1 493 GLN 493 519 519 GLN GLN A . n A 1 494 VAL 494 520 520 VAL VAL A . n A 1 495 LEU 495 521 521 LEU LEU A . n A 1 496 SER 496 522 522 SER SER A . n A 1 497 GLY 497 523 523 GLY GLY A . n A 1 498 THR 498 524 524 THR THR A . n A 1 499 GLU 499 525 525 GLU GLU A . n A 1 500 PHE 500 526 526 PHE PHE A . n A 1 501 SER 501 527 527 SER SER A . n A 1 502 ALA 502 528 528 ALA ALA A . n A 1 503 ILE 503 529 529 ILE ILE A . n A 1 504 PRO 504 530 530 PRO PRO A . n A 1 505 HIS 505 531 531 HIS HIS A . n A 1 506 VAL 506 532 532 VAL VAL A . n A 1 507 LYS 507 533 533 LYS LYS A . n A 1 508 TYR 508 534 534 TYR TYR A . n A 1 509 LEU 509 535 535 LEU LEU A . n A 1 510 ASP 510 536 536 ASP ASP A . n A 1 511 LEU 511 537 537 LEU LEU A . n A 1 512 THR 512 538 538 THR THR A . n A 1 513 ASN 513 539 539 ASN ASN A . n A 1 514 ASN 514 540 540 ASN ASN A . n A 1 515 ARG 515 541 541 ARG ARG A . n A 1 516 LEU 516 542 542 LEU LEU A . n A 1 517 ASP 517 543 543 ASP ASP A . n A 1 518 PHE 518 544 544 PHE PHE A . n A 1 519 ASP 519 545 545 ASP ASP A . n A 1 520 ASN 520 546 546 ASN ASN A . n A 1 521 ALA 521 547 547 ALA ALA A . n A 1 522 SER 522 548 548 SER SER A . n A 1 523 ALA 523 549 549 ALA ALA A . n A 1 524 LEU 524 550 550 LEU LEU A . n A 1 525 THR 525 551 551 THR THR A . n A 1 526 GLU 526 552 552 GLU GLU A . n A 1 527 LEU 527 553 553 LEU LEU A . n A 1 528 SER 528 554 554 SER SER A . n A 1 529 ASP 529 555 555 ASP ASP A . n A 1 530 LEU 530 556 556 LEU LEU A . n A 1 531 GLU 531 557 557 GLU GLU A . n A 1 532 VAL 532 558 558 VAL VAL A . n A 1 533 LEU 533 559 559 LEU LEU A . n A 1 534 ASP 534 560 560 ASP ASP A . n A 1 535 LEU 535 561 561 LEU LEU A . n A 1 536 SER 536 562 562 SER SER A . n A 1 537 TYR 537 563 563 TYR TYR A . n A 1 538 ASN 538 564 564 ASN ASN A . n A 1 539 SER 539 565 565 SER SER A . n A 1 540 HIS 540 566 566 HIS HIS A . n A 1 541 TYR 541 567 567 TYR TYR A . n A 1 542 PHE 542 568 568 PHE PHE A . n A 1 543 ARG 543 569 569 ARG ARG A . n A 1 544 ILE 544 570 570 ILE ILE A . n A 1 545 ALA 545 571 571 ALA ALA A . n A 1 546 GLY 546 572 572 GLY GLY A . n A 1 547 VAL 547 573 573 VAL VAL A . n A 1 548 THR 548 574 574 THR THR A . n A 1 549 HIS 549 575 575 HIS HIS A . n A 1 550 HIS 550 576 576 HIS HIS A . n A 1 551 LEU 551 577 577 LEU LEU A . n A 1 552 GLU 552 578 578 GLU GLU A . n A 1 553 PHE 553 579 579 PHE PHE A . n A 1 554 ILE 554 580 580 ILE ILE A . n A 1 555 GLN 555 581 581 GLN GLN A . n A 1 556 ASN 556 582 582 ASN ASN A . n A 1 557 PHE 557 583 583 PHE PHE A . n A 1 558 THR 558 584 584 THR THR A . n A 1 559 ASN 559 585 585 ASN ASN A . n A 1 560 LEU 560 586 586 LEU LEU A . n A 1 561 LYS 561 587 587 LYS LYS A . n A 1 562 VAL 562 588 588 VAL VAL A . n A 1 563 LEU 563 589 589 LEU LEU A . n A 1 564 ASN 564 590 590 ASN ASN A . n A 1 565 LEU 565 591 591 LEU LEU A . n A 1 566 SER 566 592 592 SER SER A . n A 1 567 HIS 567 593 593 HIS HIS A . n A 1 568 ASN 568 594 594 ASN ASN A . n A 1 569 ASN 569 595 595 ASN ASN A . n A 1 570 ILE 570 596 596 ILE ILE A . n A 1 571 TYR 571 597 597 TYR TYR A . n A 1 572 THR 572 598 598 THR THR A . n A 1 573 LEU 573 599 599 LEU LEU A . n A 1 574 THR 574 600 600 THR THR A . n A 1 575 ASP 575 601 601 ASP ASP A . n A 1 576 LYS 576 602 602 LYS LYS A . n A 1 577 TYR 577 603 603 TYR TYR A . n A 1 578 ASN 578 604 604 ASN ASN A . n A 1 579 LEU 579 605 605 LEU LEU A . n A 1 580 GLU 580 606 606 GLU GLU A . n A 1 581 SER 581 607 607 SER SER A . n A 1 582 LYS 582 608 608 LYS LYS A . n A 1 583 SER 583 609 609 SER SER A . n A 1 584 LEU 584 610 610 LEU LEU A . n A 1 585 VAL 585 611 611 VAL VAL A . n A 1 586 GLU 586 612 612 GLU GLU A . n A 1 587 LEU 587 613 613 LEU LEU A . n A 1 588 VAL 588 614 614 VAL VAL A . n A 1 589 PHE 589 615 615 PHE PHE A . n A 1 590 SER 590 616 616 SER SER A . n A 1 591 GLY 591 617 617 GLY GLY A . n A 1 592 ASN 592 618 618 ASN ASN A . n A 1 593 ARG 593 619 619 ARG ARG A . n A 1 594 LEU 594 620 620 LEU LEU A . n A 1 595 ASP 595 621 621 ASP ASP A . n A 1 596 ILE 596 622 622 ILE ILE A . n A 1 597 LEU 597 623 623 LEU LEU A . n A 1 598 TRP 598 624 624 TRP TRP A . n A 1 599 ASN 599 625 625 ASN ASN A . n A 1 600 ASP 600 626 626 ASP ASP A . n A 1 601 ASP 601 627 627 ASP ASP A . n A 1 602 ASP 602 628 628 ASP ASP A . n A 1 603 ASN 603 629 629 ASN ASN A . n A 1 604 ARG 604 630 630 ARG ARG A . n A 1 605 TYR 605 631 631 TYR TYR A . n A 1 606 ILE 606 632 632 ILE ILE A . n A 1 607 SER 607 633 633 SER SER A . n A 1 608 ILE 608 634 634 ILE ILE A . n A 1 609 PHE 609 635 635 PHE PHE A . n A 1 610 LYS 610 636 636 LYS LYS A . n A 1 611 GLY 611 637 637 GLY GLY A . n A 1 612 LEU 612 638 638 LEU LEU A . n A 1 613 LYS 613 639 639 LYS LYS A . n A 1 614 ASN 614 640 640 ASN ASN A . n A 1 615 LEU 615 641 641 LEU LEU A . n A 1 616 THR 616 642 642 THR THR A . n A 1 617 ARG 617 643 643 ARG ARG A . n A 1 618 LEU 618 644 644 LEU LEU A . n A 1 619 ASP 619 645 645 ASP ASP A . n A 1 620 LEU 620 646 646 LEU LEU A . n A 1 621 SER 621 647 647 SER SER A . n A 1 622 LEU 622 648 648 LEU LEU A . n A 1 623 ASN 623 649 649 ASN ASN A . n A 1 624 ARG 624 650 650 ARG ARG A . n A 1 625 LEU 625 651 651 LEU LEU A . n A 1 626 LYS 626 652 652 LYS LYS A . n A 1 627 HIS 627 653 653 HIS HIS A . n A 1 628 ILE 628 654 654 ILE ILE A . n A 1 629 PRO 629 655 655 PRO PRO A . n A 1 630 ASN 630 656 656 ASN ASN A . n A 1 631 GLU 631 657 657 GLU GLU A . n A 1 632 ALA 632 658 658 ALA ALA A . n A 1 633 PHE 633 659 659 PHE PHE A . n A 1 634 LEU 634 660 660 LEU LEU A . n A 1 635 ASN 635 661 661 ASN ASN A . n A 1 636 LEU 636 662 662 LEU LEU A . n A 1 637 PRO 637 663 663 PRO PRO A . n A 1 638 ALA 638 664 664 ALA ALA A . n A 1 639 SER 639 665 665 SER SER A . n A 1 640 LEU 640 666 666 LEU LEU A . n A 1 641 THR 641 667 667 THR THR A . n A 1 642 GLU 642 668 668 GLU GLU A . n A 1 643 LEU 643 669 669 LEU LEU A . n A 1 644 HIS 644 670 670 HIS HIS A . n A 1 645 ILE 645 671 671 ILE ILE A . n A 1 646 ASN 646 672 672 ASN ASN A . n A 1 647 ASP 647 673 673 ASP ASP A . n A 1 648 ASN 648 674 674 ASN ASN A . n A 1 649 MET 649 675 675 MET MET A . n A 1 650 LEU 650 676 676 LEU LEU A . n A 1 651 LYS 651 677 677 LYS LYS A . n A 1 652 PHE 652 678 678 PHE PHE A . n A 1 653 PHE 653 679 679 PHE PHE A . n A 1 654 ASN 654 680 680 ASN ASN A . n A 1 655 TRP 655 681 681 TRP TRP A . n A 1 656 THR 656 682 682 THR THR A . n A 1 657 LEU 657 683 683 LEU LEU A . n A 1 658 LEU 658 684 684 LEU LEU A . n A 1 659 GLN 659 685 685 GLN GLN A . n A 1 660 GLN 660 686 686 GLN GLN A . n A 1 661 PHE 661 687 687 PHE PHE A . n A 1 662 PRO 662 688 688 PRO PRO A . n A 1 663 ARG 663 689 689 ARG ARG A . n A 1 664 LEU 664 690 690 LEU LEU A . n A 1 665 GLU 665 691 691 GLU GLU A . n A 1 666 LEU 666 692 692 LEU LEU A . n A 1 667 LEU 667 693 693 LEU LEU A . n A 1 668 ASP 668 694 694 ASP ASP A . n A 1 669 LEU 669 695 695 LEU LEU A . n A 1 670 ARG 670 696 696 ARG ARG A . n A 1 671 GLY 671 697 697 GLY GLY A . n A 1 672 ASN 672 698 698 ASN ASN A . n A 1 673 LYS 673 699 699 LYS LYS A . n A 1 674 LEU 674 700 700 LEU LEU A . n A 1 675 LEU 675 701 701 LEU LEU A . n A 1 676 PHE 676 702 702 PHE PHE A . n A 1 677 LEU 677 703 703 LEU LEU A . n A 1 678 THR 678 704 704 THR THR A . n A 1 679 ASP 679 705 705 ASP ASP A . n A 1 680 SER 680 706 706 SER SER A . n A 1 681 LEU 681 707 707 LEU LEU A . n A 1 682 SER 682 708 708 SER SER A . n A 1 683 ASP 683 709 709 ASP ASP A . n A 1 684 PHE 684 710 710 PHE PHE A . n A 1 685 THR 685 711 711 THR THR A . n A 1 686 SER 686 712 712 SER SER A . n A 1 687 SER 687 713 713 SER SER A . n A 1 688 LEU 688 714 714 LEU LEU A . n A 1 689 ARG 689 715 715 ARG ARG A . n A 1 690 THR 690 716 716 THR THR A . n A 1 691 LEU 691 717 717 LEU LEU A . n A 1 692 LEU 692 718 718 LEU LEU A . n A 1 693 LEU 693 719 719 LEU LEU A . n A 1 694 SER 694 720 720 SER SER A . n A 1 695 HIS 695 721 721 HIS HIS A . n A 1 696 ASN 696 722 722 ASN ASN A . n A 1 697 ARG 697 723 723 ARG ARG A . n A 1 698 ILE 698 724 724 ILE ILE A . n A 1 699 SER 699 725 725 SER SER A . n A 1 700 HIS 700 726 726 HIS HIS A . n A 1 701 LEU 701 727 727 LEU LEU A . n A 1 702 PRO 702 728 728 PRO PRO A . n A 1 703 SER 703 729 729 SER SER A . n A 1 704 GLY 704 730 730 GLY GLY A . n A 1 705 PHE 705 731 731 PHE PHE A . n A 1 706 LEU 706 732 732 LEU LEU A . n A 1 707 SER 707 733 ? ? ? A . n A 1 708 GLU 708 734 ? ? ? A . n A 1 709 VAL 709 735 ? ? ? A . n A 1 710 SER 710 736 736 SER SER A . n A 1 711 SER 711 737 737 SER SER A . n A 1 712 LEU 712 738 738 LEU LEU A . n A 1 713 LYS 713 739 739 LYS LYS A . n A 1 714 HIS 714 740 740 HIS HIS A . n A 1 715 LEU 715 741 741 LEU LEU A . n A 1 716 ASP 716 742 742 ASP ASP A . n A 1 717 LEU 717 743 743 LEU LEU A . n A 1 718 SER 718 744 744 SER SER A . n A 1 719 SER 719 745 745 SER SER A . n A 1 720 ASN 720 746 746 ASN ASN A . n A 1 721 LEU 721 747 747 LEU LEU A . n A 1 722 LEU 722 748 748 LEU LEU A . n A 1 723 LYS 723 749 749 LYS LYS A . n A 1 724 THR 724 750 750 THR THR A . n A 1 725 ILE 725 751 751 ILE ILE A . n A 1 726 ASN 726 752 752 ASN ASN A . n A 1 727 LYS 727 753 753 LYS LYS A . n A 1 728 SER 728 754 754 SER SER A . n A 1 729 ALA 729 755 755 ALA ALA A . n A 1 730 LEU 730 756 756 LEU LEU A . n A 1 731 GLU 731 757 ? ? ? A . n A 1 732 THR 732 758 ? ? ? A . n A 1 733 LYS 733 759 ? ? ? A . n A 1 734 THR 734 760 ? ? ? A . n A 1 735 THR 735 761 ? ? ? A . n A 1 736 THR 736 762 ? ? ? A . n A 1 737 LYS 737 763 763 LYS LYS A . n A 1 738 LEU 738 764 764 LEU LEU A . n A 1 739 SER 739 765 765 SER SER A . n A 1 740 MET 740 766 766 MET MET A . n A 1 741 LEU 741 767 767 LEU LEU A . n A 1 742 GLU 742 768 768 GLU GLU A . n A 1 743 LEU 743 769 769 LEU LEU A . n A 1 744 HIS 744 770 770 HIS HIS A . n A 1 745 GLY 745 771 771 GLY GLY A . n A 1 746 ASN 746 772 772 ASN ASN A . n A 1 747 PRO 747 773 773 PRO PRO A . n A 1 748 PHE 748 774 774 PHE PHE A . n A 1 749 GLU 749 775 775 GLU GLU A . n A 1 750 CYS 750 776 776 CYS CYS A . n A 1 751 THR 751 777 777 THR THR A . n A 1 752 CYS 752 778 778 CYS CYS A . n A 1 753 ASP 753 779 779 ASP ASP A . n A 1 754 ILE 754 780 780 ILE ILE A . n A 1 755 GLY 755 781 781 GLY GLY A . n A 1 756 ASP 756 782 782 ASP ASP A . n A 1 757 PHE 757 783 783 PHE PHE A . n A 1 758 ARG 758 784 784 ARG ARG A . n A 1 759 ARG 759 785 785 ARG ARG A . n A 1 760 TRP 760 786 786 TRP TRP A . n A 1 761 MET 761 787 787 MET MET A . n A 1 762 ASP 762 788 788 ASP ASP A . n A 1 763 GLU 763 789 789 GLU GLU A . n A 1 764 HIS 764 790 790 HIS HIS A . n A 1 765 LEU 765 791 791 LEU LEU A . n A 1 766 ASN 766 792 792 ASN ASN A . n A 1 767 VAL 767 793 793 VAL VAL A . n A 1 768 LYS 768 794 794 LYS LYS A . n A 1 769 ILE 769 795 795 ILE ILE A . n A 1 770 PRO 770 796 796 PRO PRO A . n A 1 771 ARG 771 797 797 ARG ARG A . n A 1 772 LEU 772 798 798 LEU LEU A . n A 1 773 VAL 773 799 799 VAL VAL A . n A 1 774 ASP 774 800 800 ASP ASP A . n A 1 775 VAL 775 801 801 VAL VAL A . n A 1 776 ILE 776 802 802 ILE ILE A . n A 1 777 CYS 777 803 803 CYS CYS A . n A 1 778 ALA 778 804 804 ALA ALA A . n A 1 779 SER 779 805 805 SER SER A . n A 1 780 PRO 780 806 806 PRO PRO A . n A 1 781 GLY 781 807 807 GLY GLY A . n A 1 782 ASP 782 808 808 ASP ASP A . n A 1 783 GLN 783 809 809 GLN GLN A . n A 1 784 ARG 784 810 810 ARG ARG A . n A 1 785 GLY 785 811 811 GLY GLY A . n A 1 786 LYS 786 812 812 LYS LYS A . n A 1 787 SER 787 813 813 SER SER A . n A 1 788 ILE 788 814 814 ILE ILE A . n A 1 789 VAL 789 815 815 VAL VAL A . n A 1 790 SER 790 816 816 SER SER A . n A 1 791 LEU 791 817 817 LEU LEU A . n A 1 792 GLU 792 818 818 GLU GLU A . n A 1 793 LEU 793 819 819 LEU LEU A . n A 1 794 THR 794 820 820 THR THR A . n A 1 795 THR 795 821 821 THR THR A . n A 1 796 CYS 796 822 822 CYS CYS A . n A 1 797 VAL 797 823 823 VAL VAL A . n A 1 798 SER 798 824 ? ? ? A . n A 1 799 ASP 799 825 ? ? ? A . n A 1 800 VAL 800 826 ? ? ? A . n A 1 801 THR 801 827 ? ? ? A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 901 1070 NAG NAG A . C 2 NAG 1 902 1080 NAG NAG A . D 2 NAG 2 903 1081 NAG NAG A . E 3 BMA 3 904 1082 BMA BMA A . F 4 MAN 4 905 1083 MAN MAN A . G 2 NAG 1 906 1110 NAG NAG A . H 2 NAG 1 907 1120 NAG NAG A . I 2 NAG 1 908 1140 NAG NAG A . J 2 NAG 2 909 1141 NAG NAG A . K 2 NAG 1 910 1150 NAG NAG A . L 2 NAG 1 911 1160 NAG NAG A . M 2 NAG 1 912 1170 NAG NAG A . N 2 NAG 2 913 1171 NAG NAG A . O 3 BMA 3 914 1172 BMA BMA A . P 4 MAN 4 915 1173 MAN MAN A . Q 4 MAN 5 916 1174 MAN MAN A . R 2 NAG 1 917 1180 NAG NAG A . S 5 SO4 1 918 1 SO4 SO4 A . T 5 SO4 1 919 2 SO4 SO4 A . U 5 SO4 1 920 3 SO4 SO4 A . V 6 MES 1 921 1 MES MES A . W 7 HOH 1 1001 95 HOH HOH A . W 7 HOH 2 1002 77 HOH HOH A . W 7 HOH 3 1003 50 HOH HOH A . W 7 HOH 4 1004 10 HOH HOH A . W 7 HOH 5 1005 72 HOH HOH A . W 7 HOH 6 1006 63 HOH HOH A . W 7 HOH 7 1007 65 HOH HOH A . W 7 HOH 8 1008 15 HOH HOH A . W 7 HOH 9 1009 47 HOH HOH A . W 7 HOH 10 1010 20 HOH HOH A . W 7 HOH 11 1011 14 HOH HOH A . W 7 HOH 12 1012 107 HOH HOH A . W 7 HOH 13 1013 73 HOH HOH A . W 7 HOH 14 1014 43 HOH HOH A . W 7 HOH 15 1015 48 HOH HOH A . W 7 HOH 16 1016 6 HOH HOH A . W 7 HOH 17 1017 16 HOH HOH A . W 7 HOH 18 1018 31 HOH HOH A . W 7 HOH 19 1019 74 HOH HOH A . W 7 HOH 20 1020 2 HOH HOH A . W 7 HOH 21 1021 62 HOH HOH A . W 7 HOH 22 1022 42 HOH HOH A . W 7 HOH 23 1023 1 HOH HOH A . W 7 HOH 24 1024 108 HOH HOH A . W 7 HOH 25 1025 45 HOH HOH A . W 7 HOH 26 1026 30 HOH HOH A . W 7 HOH 27 1027 38 HOH HOH A . W 7 HOH 28 1028 32 HOH HOH A . W 7 HOH 29 1029 4 HOH HOH A . W 7 HOH 30 1030 23 HOH HOH A . W 7 HOH 31 1031 41 HOH HOH A . W 7 HOH 32 1032 89 HOH HOH A . W 7 HOH 33 1033 19 HOH HOH A . W 7 HOH 34 1034 81 HOH HOH A . W 7 HOH 35 1035 13 HOH HOH A . W 7 HOH 36 1036 84 HOH HOH A . W 7 HOH 37 1037 12 HOH HOH A . W 7 HOH 38 1038 110 HOH HOH A . W 7 HOH 39 1039 79 HOH HOH A . W 7 HOH 40 1040 11 HOH HOH A . W 7 HOH 41 1041 70 HOH HOH A . W 7 HOH 42 1042 46 HOH HOH A . W 7 HOH 43 1043 36 HOH HOH A . W 7 HOH 44 1044 44 HOH HOH A . W 7 HOH 45 1045 3 HOH HOH A . W 7 HOH 46 1046 80 HOH HOH A . W 7 HOH 47 1047 39 HOH HOH A . W 7 HOH 48 1048 58 HOH HOH A . W 7 HOH 49 1049 67 HOH HOH A . W 7 HOH 50 1050 17 HOH HOH A . W 7 HOH 51 1051 90 HOH HOH A . W 7 HOH 52 1052 55 HOH HOH A . W 7 HOH 53 1053 18 HOH HOH A . W 7 HOH 54 1054 53 HOH HOH A . W 7 HOH 55 1055 52 HOH HOH A . W 7 HOH 56 1056 5 HOH HOH A . W 7 HOH 57 1057 26 HOH HOH A . W 7 HOH 58 1058 22 HOH HOH A . W 7 HOH 59 1059 27 HOH HOH A . W 7 HOH 60 1060 85 HOH HOH A . W 7 HOH 61 1061 51 HOH HOH A . W 7 HOH 62 1062 92 HOH HOH A . W 7 HOH 63 1063 24 HOH HOH A . W 7 HOH 64 1064 35 HOH HOH A . W 7 HOH 65 1065 59 HOH HOH A . W 7 HOH 66 1066 37 HOH HOH A . W 7 HOH 67 1067 68 HOH HOH A . W 7 HOH 68 1068 8 HOH HOH A . W 7 HOH 69 1069 69 HOH HOH A . W 7 HOH 70 1070 88 HOH HOH A . W 7 HOH 71 1071 93 HOH HOH A . W 7 HOH 72 1072 91 HOH HOH A . W 7 HOH 73 1073 87 HOH HOH A . W 7 HOH 74 1074 33 HOH HOH A . W 7 HOH 75 1075 56 HOH HOH A . W 7 HOH 76 1076 64 HOH HOH A . W 7 HOH 77 1077 71 HOH HOH A . W 7 HOH 78 1078 54 HOH HOH A . W 7 HOH 79 1079 61 HOH HOH A . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 4970 ? 1 MORE 50 ? 1 'SSA (A^2)' 34180 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2016-03-09 2 'Structure model' 1 1 2016-06-22 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group Other # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0073 1 ? 'data processing' ? ? ? ? ? ? ? ? ? ? ? XDS ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? . 4 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OD2 A ASP 694 ? ? NH1 A ARG 696 ? ? 2.02 2 1 OD1 A ASN 95 ? ? N A GLU 133 ? ? 2.16 3 1 ND2 A ASN 416 ? ? C2 A NAG 907 ? ? 2.18 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 C A LEU 137 ? ? N A PRO 138 ? ? CD A PRO 138 ? ? 142.32 128.40 13.92 2.10 Y 2 1 C A ARG 472 ? ? N A PRO 473 ? ? CD A PRO 473 ? ? 141.06 128.40 12.66 2.10 Y # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 GLN A 41 ? ? 88.11 158.71 2 1 CYS A 49 ? ? -142.75 56.08 3 1 GLN A 87 ? ? 66.24 -59.04 4 1 PRO A 141 ? ? -35.93 117.33 5 1 ILE A 170 ? ? 70.11 -54.96 6 1 CYS A 181 ? ? -106.29 47.04 7 1 PHE A 183 ? ? -34.82 125.88 8 1 SER A 214 ? ? 71.86 -37.58 9 1 PHE A 261 ? ? 2.85 109.65 10 1 LEU A 286 ? ? -92.19 59.87 11 1 SER A 296 ? ? 61.18 63.63 12 1 TYR A 322 ? ? -118.39 58.72 13 1 SER A 329 ? ? -141.72 56.99 14 1 SER A 360 ? ? -49.36 153.94 15 1 VAL A 378 ? ? 77.67 105.41 16 1 ASN A 416 ? ? -91.95 43.91 17 1 HIS A 464 ? ? 78.03 -7.51 18 1 ASN A 466 ? ? 138.01 -138.01 19 1 PHE A 467 ? ? 106.47 -22.93 20 1 TYR A 468 ? ? 82.76 13.45 21 1 ASN A 491 ? ? -115.88 -161.58 22 1 ASN A 546 ? ? -164.15 108.93 23 1 ASP A 601 ? ? 69.30 -58.80 24 1 ASN A 618 ? ? -102.91 -159.98 25 1 ASP A 627 ? ? 130.71 -164.49 26 1 ASN A 674 ? ? -111.69 -152.94 27 1 PHE A 687 ? ? -116.12 73.37 28 1 ASN A 698 ? ? -119.36 -159.33 29 1 ASN A 746 ? ? -114.52 -154.29 30 1 ILE A 814 ? ? -63.20 4.55 31 1 THR A 821 ? ? -55.99 -1.29 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 ASN _pdbx_validate_peptide_omega.auth_asym_id_1 A _pdbx_validate_peptide_omega.auth_seq_id_1 466 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 PHE _pdbx_validate_peptide_omega.auth_asym_id_2 A _pdbx_validate_peptide_omega.auth_seq_id_2 467 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega -149.43 # _pdbx_validate_planes.id 1 _pdbx_validate_planes.PDB_model_num 1 _pdbx_validate_planes.auth_comp_id TYR _pdbx_validate_planes.auth_asym_id A _pdbx_validate_planes.auth_seq_id 353 _pdbx_validate_planes.PDB_ins_code ? _pdbx_validate_planes.label_alt_id ? _pdbx_validate_planes.rmsd 0.057 _pdbx_validate_planes.type 'SIDE CHAIN' # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLU 27 ? A GLU 1 2 1 Y 1 A GLU 28 ? A GLU 2 3 1 Y 1 A ASN 29 ? A ASN 3 4 1 Y 1 A PHE 30 ? A PHE 4 5 1 Y 1 A SER 31 ? A SER 5 6 1 Y 1 A ARG 32 ? A ARG 6 7 1 Y 1 A GLN 101 ? A GLN 75 8 1 Y 1 A HIS 102 ? A HIS 76 9 1 Y 1 A GLN 103 ? A GLN 77 10 1 Y 1 A ASN 104 ? A ASN 78 11 1 Y 1 A GLY 105 ? A GLY 79 12 1 Y 1 A ASN 106 ? A ASN 80 13 1 Y 1 A PRO 107 ? A PRO 81 14 1 Y 1 A GLY 108 ? A GLY 82 15 1 Y 1 A ILE 109 ? A ILE 83 16 1 Y 1 A GLN 110 ? A GLN 84 17 1 Y 1 A SER 111 ? A SER 85 18 1 Y 1 A ASN 112 ? A ASN 86 19 1 Y 1 A LYS 435 ? A LYS 409 20 1 Y 1 A ASP 436 ? A ASP 410 21 1 Y 1 A THR 437 ? A THR 411 22 1 Y 1 A ARG 438 ? A ARG 412 23 1 Y 1 A GLN 439 ? A GLN 413 24 1 Y 1 A SER 440 ? A SER 414 25 1 Y 1 A TYR 441 ? A TYR 415 26 1 Y 1 A ALA 442 ? A ALA 416 27 1 Y 1 A ASN 452 ? A ASN 426 28 1 Y 1 A GLN 453 ? A GLN 427 29 1 Y 1 A SER 454 ? A SER 428 30 1 Y 1 A ASN 455 ? A ASN 429 31 1 Y 1 A SER 456 ? A SER 430 32 1 Y 1 A THR 457 ? A THR 431 33 1 Y 1 A ASP 458 ? A ASP 432 34 1 Y 1 A PHE 459 ? A PHE 433 35 1 Y 1 A GLU 460 ? A GLU 434 36 1 Y 1 A PHE 461 ? A PHE 435 37 1 Y 1 A ASP 462 ? A ASP 436 38 1 Y 1 A SER 733 ? A SER 707 39 1 Y 1 A GLU 734 ? A GLU 708 40 1 Y 1 A VAL 735 ? A VAL 709 41 1 Y 1 A GLU 757 ? A GLU 731 42 1 Y 1 A THR 758 ? A THR 732 43 1 Y 1 A LYS 759 ? A LYS 733 44 1 Y 1 A THR 760 ? A THR 734 45 1 Y 1 A THR 761 ? A THR 735 46 1 Y 1 A THR 762 ? A THR 736 47 1 Y 1 A SER 824 ? A SER 798 48 1 Y 1 A ASP 825 ? A ASP 799 49 1 Y 1 A VAL 826 ? A VAL 800 50 1 Y 1 A THR 827 ? A THR 801 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 BETA-D-MANNOSE BMA 4 ALPHA-D-MANNOSE MAN 5 'SULFATE ION' SO4 6 '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' MES 7 water HOH #