data_5HBV # _entry.id 5HBV # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5HBV WWPDB D_1000216802 # _pdbx_database_related.db_name PDB _pdbx_database_related.details '5HBT is a complex with human nAChR, and this is with mouse nAChR.' _pdbx_database_related.db_id 5HBT _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5HBV _pdbx_database_status.recvd_initial_deposition_date 2016-01-02 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal _audit_author.identifier_ORCID 'Noridomi, K.' 1 ? 'Watanabe, G.' 2 ? 'Hansen, M.N.' 3 ? 'Han, G.W.' 4 ? 'Chen, L.' 5 ? # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev Elife _citation.journal_id_ASTM ? _citation.journal_id_CSD ? _citation.journal_id_ISSN 2050-084X _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 6 _citation.language ? _citation.page_first ? _citation.page_last ? _citation.title 'Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications.' _citation.year 2017 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.7554/eLife.23043 _citation.pdbx_database_id_PubMed 28440223 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Noridomi, K.' 1 primary 'Watanabe, G.' 2 primary 'Hansen, M.N.' 3 primary 'Han, G.W.' 4 primary 'Chen, L.' 5 # _cell.entry_id 5HBV _cell.length_a 159.905 _cell.length_b 42.024 _cell.length_c 137.583 _cell.angle_alpha 90.00 _cell.angle_beta 116.46 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? # _symmetry.entry_id 5HBV _symmetry.space_group_name_H-M 'C 1 2 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 5 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer nat 'Alpha-bungarotoxin isoform V31' 8033.334 1 ? ? 'UNP residues 22-95' ? 2 polymer man 'Acetylcholine receptor subunit alpha 1' 24729.012 1 ? 'V8E, W149R, V155A' 'UNP residues 22-231' ? 3 polymer nat 'Fab35, Light Chain' 23392.982 1 ? ? ? ? 4 polymer nat 'Fab35, Heavy Chain' 23879.758 1 ? ? ? ? 5 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 2 ? ? ? ? 6 non-polymer man BETA-D-MANNOSE 180.156 1 ? ? ? ? 7 non-polymer man ALPHA-D-MANNOSE 180.156 6 ? ? ? ? 8 water nat water 18.015 46 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'BGTX V31,Long neurotoxin 1' # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no IVCHTTATSPISAVTCPPGENLCYRKMWCDVFCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNPHPKQRPG IVCHTTATSPISAVTCPPGENLCYRKMWCDVFCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNPHPKQRPG A ? 2 'polypeptide(L)' no no ;KSEHETRLEAKLFEDYSSVVRPVEDHREIVQVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIH IPSEKIWRPDVVLYNNADGDFAIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTRTYDGSAVAIN PESDQPDLSNFMESGEWVIKEARGWKHWVFYSCCPTTPYLDITYHFVMQRLP ; ;KSEHETRLEAKLFEDYSSVVRPVEDHREIVQVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIH IPSEKIWRPDVVLYNNADGDFAIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTRTYDGSAVAIN PESDQPDLSNFMESGEWVIKEARGWKHWVFYSCCPTTPYLDITYHFVMQRLP ; B ? 3 'polypeptide(L)' no no ;DIVITQSPSLLSASVGDRVTLTCKGSQNIDNYLAWYQQKLGEAPKLLIYKTNSLQTGIPSRFSGSGSGTDYTLTISSLHS EDLATYYCYQYINGYTFGTGTKLELKRADAAPTVSIFPPSTEQLATGGASVVCLMNNFYPRDISVKWKIDGTERRDGVLD SVTDQDSKDSTYSMSSTLSLTKADYESHNLYTCEVVHKTSSSPVVKSFNRNEC ; ;DIVITQSPSLLSASVGDRVTLTCKGSQNIDNYLAWYQQKLGEAPKLLIYKTNSLQTGIPSRFSGSGSGTDYTLTISSLHS EDLATYYCYQYINGYTFGTGTKLELKRADAAPTVSIFPPSTEQLATGGASVVCLMNNFYPRDISVKWKIDGTERRDGVLD SVTDQDSKDSTYSMSSTLSLTKADYESHNLYTCEVVHKTSSSPVVKSFNRNEC ; C ? 4 'polypeptide(L)' no no ;EVQLQESGPGLVQPSETLSLTCTVSGFSLTSYSVSWLRQPSGKGPEWMGRMWDDGGTVYNSGLKSRLSISRDTSKNQVFL KMNSLQTDDTGTYYCTRDERIRAINWFAYWGQGTLVTVSSAETTAPSVYPLAPGTALKSNSMVTLGCLVKGYFPEPVTVT WNSGALSSGVHTFPAVLQSGLYTLTSSVTVPSSTWPSQTVTCNVAHPGQQHQRWTRKLC ; ;EVQLQESGPGLVQPSETLSLTCTVSGFSLTSYSVSWLRQPSGKGPEWMGRMWDDGGTVYNSGLKSRLSISRDTSKNQVFL KMNSLQTDDTGTYYCTRDERIRAINWFAYWGQGTLVTVSSAETTAPSVYPLAPGTALKSNSMVTLGCLVKGYFPEPVTVT WNSGALSSGVHTFPAVLQSGLYTLTSSVTVPSSTWPSQTVTCNVAHPGQQHQRWTRKLC ; D ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ILE n 1 2 VAL n 1 3 CYS n 1 4 HIS n 1 5 THR n 1 6 THR n 1 7 ALA n 1 8 THR n 1 9 SER n 1 10 PRO n 1 11 ILE n 1 12 SER n 1 13 ALA n 1 14 VAL n 1 15 THR n 1 16 CYS n 1 17 PRO n 1 18 PRO n 1 19 GLY n 1 20 GLU n 1 21 ASN n 1 22 LEU n 1 23 CYS n 1 24 TYR n 1 25 ARG n 1 26 LYS n 1 27 MET n 1 28 TRP n 1 29 CYS n 1 30 ASP n 1 31 VAL n 1 32 PHE n 1 33 CYS n 1 34 SER n 1 35 SER n 1 36 ARG n 1 37 GLY n 1 38 LYS n 1 39 VAL n 1 40 VAL n 1 41 GLU n 1 42 LEU n 1 43 GLY n 1 44 CYS n 1 45 ALA n 1 46 ALA n 1 47 THR n 1 48 CYS n 1 49 PRO n 1 50 SER n 1 51 LYS n 1 52 LYS n 1 53 PRO n 1 54 TYR n 1 55 GLU n 1 56 GLU n 1 57 VAL n 1 58 THR n 1 59 CYS n 1 60 CYS n 1 61 SER n 1 62 THR n 1 63 ASP n 1 64 LYS n 1 65 CYS n 1 66 ASN n 1 67 PRO n 1 68 HIS n 1 69 PRO n 1 70 LYS n 1 71 GLN n 1 72 ARG n 1 73 PRO n 1 74 GLY n 2 1 LYS n 2 2 SER n 2 3 GLU n 2 4 HIS n 2 5 GLU n 2 6 THR n 2 7 ARG n 2 8 LEU n 2 9 GLU n 2 10 ALA n 2 11 LYS n 2 12 LEU n 2 13 PHE n 2 14 GLU n 2 15 ASP n 2 16 TYR n 2 17 SER n 2 18 SER n 2 19 VAL n 2 20 VAL n 2 21 ARG n 2 22 PRO n 2 23 VAL n 2 24 GLU n 2 25 ASP n 2 26 HIS n 2 27 ARG n 2 28 GLU n 2 29 ILE n 2 30 VAL n 2 31 GLN n 2 32 VAL n 2 33 THR n 2 34 VAL n 2 35 GLY n 2 36 LEU n 2 37 GLN n 2 38 LEU n 2 39 ILE n 2 40 GLN n 2 41 LEU n 2 42 ILE n 2 43 ASN n 2 44 VAL n 2 45 ASP n 2 46 GLU n 2 47 VAL n 2 48 ASN n 2 49 GLN n 2 50 ILE n 2 51 VAL n 2 52 THR n 2 53 THR n 2 54 ASN n 2 55 VAL n 2 56 ARG n 2 57 LEU n 2 58 LYS n 2 59 GLN n 2 60 GLN n 2 61 TRP n 2 62 VAL n 2 63 ASP n 2 64 TYR n 2 65 ASN n 2 66 LEU n 2 67 LYS n 2 68 TRP n 2 69 ASN n 2 70 PRO n 2 71 ASP n 2 72 ASP n 2 73 TYR n 2 74 GLY n 2 75 GLY n 2 76 VAL n 2 77 LYS n 2 78 LYS n 2 79 ILE n 2 80 HIS n 2 81 ILE n 2 82 PRO n 2 83 SER n 2 84 GLU n 2 85 LYS n 2 86 ILE n 2 87 TRP n 2 88 ARG n 2 89 PRO n 2 90 ASP n 2 91 VAL n 2 92 VAL n 2 93 LEU n 2 94 TYR n 2 95 ASN n 2 96 ASN n 2 97 ALA n 2 98 ASP n 2 99 GLY n 2 100 ASP n 2 101 PHE n 2 102 ALA n 2 103 ILE n 2 104 VAL n 2 105 LYS n 2 106 PHE n 2 107 THR n 2 108 LYS n 2 109 VAL n 2 110 LEU n 2 111 LEU n 2 112 ASP n 2 113 TYR n 2 114 THR n 2 115 GLY n 2 116 HIS n 2 117 ILE n 2 118 THR n 2 119 TRP n 2 120 THR n 2 121 PRO n 2 122 PRO n 2 123 ALA n 2 124 ILE n 2 125 PHE n 2 126 LYS n 2 127 SER n 2 128 TYR n 2 129 CYS n 2 130 GLU n 2 131 ILE n 2 132 ILE n 2 133 VAL n 2 134 THR n 2 135 HIS n 2 136 PHE n 2 137 PRO n 2 138 PHE n 2 139 ASP n 2 140 GLU n 2 141 GLN n 2 142 ASN n 2 143 CYS n 2 144 SER n 2 145 MET n 2 146 LYS n 2 147 LEU n 2 148 GLY n 2 149 THR n 2 150 ARG n 2 151 THR n 2 152 TYR n 2 153 ASP n 2 154 GLY n 2 155 SER n 2 156 ALA n 2 157 VAL n 2 158 ALA n 2 159 ILE n 2 160 ASN n 2 161 PRO n 2 162 GLU n 2 163 SER n 2 164 ASP n 2 165 GLN n 2 166 PRO n 2 167 ASP n 2 168 LEU n 2 169 SER n 2 170 ASN n 2 171 PHE n 2 172 MET n 2 173 GLU n 2 174 SER n 2 175 GLY n 2 176 GLU n 2 177 TRP n 2 178 VAL n 2 179 ILE n 2 180 LYS n 2 181 GLU n 2 182 ALA n 2 183 ARG n 2 184 GLY n 2 185 TRP n 2 186 LYS n 2 187 HIS n 2 188 TRP n 2 189 VAL n 2 190 PHE n 2 191 TYR n 2 192 SER n 2 193 CYS n 2 194 CYS n 2 195 PRO n 2 196 THR n 2 197 THR n 2 198 PRO n 2 199 TYR n 2 200 LEU n 2 201 ASP n 2 202 ILE n 2 203 THR n 2 204 TYR n 2 205 HIS n 2 206 PHE n 2 207 VAL n 2 208 MET n 2 209 GLN n 2 210 ARG n 2 211 LEU n 2 212 PRO n 3 1 ASP n 3 2 ILE n 3 3 VAL n 3 4 ILE n 3 5 THR n 3 6 GLN n 3 7 SER n 3 8 PRO n 3 9 SER n 3 10 LEU n 3 11 LEU n 3 12 SER n 3 13 ALA n 3 14 SER n 3 15 VAL n 3 16 GLY n 3 17 ASP n 3 18 ARG n 3 19 VAL n 3 20 THR n 3 21 LEU n 3 22 THR n 3 23 CYS n 3 24 LYS n 3 25 GLY n 3 26 SER n 3 27 GLN n 3 28 ASN n 3 29 ILE n 3 30 ASP n 3 31 ASN n 3 32 TYR n 3 33 LEU n 3 34 ALA n 3 35 TRP n 3 36 TYR n 3 37 GLN n 3 38 GLN n 3 39 LYS n 3 40 LEU n 3 41 GLY n 3 42 GLU n 3 43 ALA n 3 44 PRO n 3 45 LYS n 3 46 LEU n 3 47 LEU n 3 48 ILE n 3 49 TYR n 3 50 LYS n 3 51 THR n 3 52 ASN n 3 53 SER n 3 54 LEU n 3 55 GLN n 3 56 THR n 3 57 GLY n 3 58 ILE n 3 59 PRO n 3 60 SER n 3 61 ARG n 3 62 PHE n 3 63 SER n 3 64 GLY n 3 65 SER n 3 66 GLY n 3 67 SER n 3 68 GLY n 3 69 THR n 3 70 ASP n 3 71 TYR n 3 72 THR n 3 73 LEU n 3 74 THR n 3 75 ILE n 3 76 SER n 3 77 SER n 3 78 LEU n 3 79 HIS n 3 80 SER n 3 81 GLU n 3 82 ASP n 3 83 LEU n 3 84 ALA n 3 85 THR n 3 86 TYR n 3 87 TYR n 3 88 CYS n 3 89 TYR n 3 90 GLN n 3 91 TYR n 3 92 ILE n 3 93 ASN n 3 94 GLY n 3 95 TYR n 3 96 THR n 3 97 PHE n 3 98 GLY n 3 99 THR n 3 100 GLY n 3 101 THR n 3 102 LYS n 3 103 LEU n 3 104 GLU n 3 105 LEU n 3 106 LYS n 3 107 ARG n 3 108 ALA n 3 109 ASP n 3 110 ALA n 3 111 ALA n 3 112 PRO n 3 113 THR n 3 114 VAL n 3 115 SER n 3 116 ILE n 3 117 PHE n 3 118 PRO n 3 119 PRO n 3 120 SER n 3 121 THR n 3 122 GLU n 3 123 GLN n 3 124 LEU n 3 125 ALA n 3 126 THR n 3 127 GLY n 3 128 GLY n 3 129 ALA n 3 130 SER n 3 131 VAL n 3 132 VAL n 3 133 CYS n 3 134 LEU n 3 135 MET n 3 136 ASN n 3 137 ASN n 3 138 PHE n 3 139 TYR n 3 140 PRO n 3 141 ARG n 3 142 ASP n 3 143 ILE n 3 144 SER n 3 145 VAL n 3 146 LYS n 3 147 TRP n 3 148 LYS n 3 149 ILE n 3 150 ASP n 3 151 GLY n 3 152 THR n 3 153 GLU n 3 154 ARG n 3 155 ARG n 3 156 ASP n 3 157 GLY n 3 158 VAL n 3 159 LEU n 3 160 ASP n 3 161 SER n 3 162 VAL n 3 163 THR n 3 164 ASP n 3 165 GLN n 3 166 ASP n 3 167 SER n 3 168 LYS n 3 169 ASP n 3 170 SER n 3 171 THR n 3 172 TYR n 3 173 SER n 3 174 MET n 3 175 SER n 3 176 SER n 3 177 THR n 3 178 LEU n 3 179 SER n 3 180 LEU n 3 181 THR n 3 182 LYS n 3 183 ALA n 3 184 ASP n 3 185 TYR n 3 186 GLU n 3 187 SER n 3 188 HIS n 3 189 ASN n 3 190 LEU n 3 191 TYR n 3 192 THR n 3 193 CYS n 3 194 GLU n 3 195 VAL n 3 196 VAL n 3 197 HIS n 3 198 LYS n 3 199 THR n 3 200 SER n 3 201 SER n 3 202 SER n 3 203 PRO n 3 204 VAL n 3 205 VAL n 3 206 LYS n 3 207 SER n 3 208 PHE n 3 209 ASN n 3 210 ARG n 3 211 ASN n 3 212 GLU n 3 213 CYS n 4 1 GLU n 4 2 VAL n 4 3 GLN n 4 4 LEU n 4 5 GLN n 4 6 GLU n 4 7 SER n 4 8 GLY n 4 9 PRO n 4 10 GLY n 4 11 LEU n 4 12 VAL n 4 13 GLN n 4 14 PRO n 4 15 SER n 4 16 GLU n 4 17 THR n 4 18 LEU n 4 19 SER n 4 20 LEU n 4 21 THR n 4 22 CYS n 4 23 THR n 4 24 VAL n 4 25 SER n 4 26 GLY n 4 27 PHE n 4 28 SER n 4 29 LEU n 4 30 THR n 4 31 SER n 4 32 TYR n 4 33 SER n 4 34 VAL n 4 35 SER n 4 36 TRP n 4 37 LEU n 4 38 ARG n 4 39 GLN n 4 40 PRO n 4 41 SER n 4 42 GLY n 4 43 LYS n 4 44 GLY n 4 45 PRO n 4 46 GLU n 4 47 TRP n 4 48 MET n 4 49 GLY n 4 50 ARG n 4 51 MET n 4 52 TRP n 4 53 ASP n 4 54 ASP n 4 55 GLY n 4 56 GLY n 4 57 THR n 4 58 VAL n 4 59 TYR n 4 60 ASN n 4 61 SER n 4 62 GLY n 4 63 LEU n 4 64 LYS n 4 65 SER n 4 66 ARG n 4 67 LEU n 4 68 SER n 4 69 ILE n 4 70 SER n 4 71 ARG n 4 72 ASP n 4 73 THR n 4 74 SER n 4 75 LYS n 4 76 ASN n 4 77 GLN n 4 78 VAL n 4 79 PHE n 4 80 LEU n 4 81 LYS n 4 82 MET n 4 83 ASN n 4 84 SER n 4 85 LEU n 4 86 GLN n 4 87 THR n 4 88 ASP n 4 89 ASP n 4 90 THR n 4 91 GLY n 4 92 THR n 4 93 TYR n 4 94 TYR n 4 95 CYS n 4 96 THR n 4 97 ARG n 4 98 ASP n 4 99 GLU n 4 100 ARG n 4 101 ILE n 4 102 ARG n 4 103 ALA n 4 104 ILE n 4 105 ASN n 4 106 TRP n 4 107 PHE n 4 108 ALA n 4 109 TYR n 4 110 TRP n 4 111 GLY n 4 112 GLN n 4 113 GLY n 4 114 THR n 4 115 LEU n 4 116 VAL n 4 117 THR n 4 118 VAL n 4 119 SER n 4 120 SER n 4 121 ALA n 4 122 GLU n 4 123 THR n 4 124 THR n 4 125 ALA n 4 126 PRO n 4 127 SER n 4 128 VAL n 4 129 TYR n 4 130 PRO n 4 131 LEU n 4 132 ALA n 4 133 PRO n 4 134 GLY n 4 135 THR n 4 136 ALA n 4 137 LEU n 4 138 LYS n 4 139 SER n 4 140 ASN n 4 141 SER n 4 142 MET n 4 143 VAL n 4 144 THR n 4 145 LEU n 4 146 GLY n 4 147 CYS n 4 148 LEU n 4 149 VAL n 4 150 LYS n 4 151 GLY n 4 152 TYR n 4 153 PHE n 4 154 PRO n 4 155 GLU n 4 156 PRO n 4 157 VAL n 4 158 THR n 4 159 VAL n 4 160 THR n 4 161 TRP n 4 162 ASN n 4 163 SER n 4 164 GLY n 4 165 ALA n 4 166 LEU n 4 167 SER n 4 168 SER n 4 169 GLY n 4 170 VAL n 4 171 HIS n 4 172 THR n 4 173 PHE n 4 174 PRO n 4 175 ALA n 4 176 VAL n 4 177 LEU n 4 178 GLN n 4 179 SER n 4 180 GLY n 4 181 LEU n 4 182 TYR n 4 183 THR n 4 184 LEU n 4 185 THR n 4 186 SER n 4 187 SER n 4 188 VAL n 4 189 THR n 4 190 VAL n 4 191 PRO n 4 192 SER n 4 193 SER n 4 194 THR n 4 195 TRP n 4 196 PRO n 4 197 SER n 4 198 GLN n 4 199 THR n 4 200 VAL n 4 201 THR n 4 202 CYS n 4 203 ASN n 4 204 VAL n 4 205 ALA n 4 206 HIS n 4 207 PRO n 4 208 GLY n 4 209 GLN n 4 210 GLN n 4 211 HIS n 4 212 GLN n 4 213 ARG n 4 214 TRP n 4 215 THR n 4 216 ARG n 4 217 LYS n 4 218 LEU n 4 219 CYS n # _entity_src_gen.entity_id 2 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 212 _entity_src_gen.gene_src_common_name Mouse _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'Chrna1, Acra' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Mus musculus' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 10090 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name Pichia _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 4919 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # loop_ _entity_src_nat.entity_id _entity_src_nat.pdbx_src_id _entity_src_nat.pdbx_alt_source_flag _entity_src_nat.pdbx_beg_seq_num _entity_src_nat.pdbx_end_seq_num _entity_src_nat.common_name _entity_src_nat.pdbx_organism_scientific _entity_src_nat.pdbx_ncbi_taxonomy_id _entity_src_nat.genus _entity_src_nat.species _entity_src_nat.strain _entity_src_nat.tissue _entity_src_nat.tissue_fraction _entity_src_nat.pdbx_secretion _entity_src_nat.pdbx_fragment _entity_src_nat.pdbx_variant _entity_src_nat.pdbx_cell_line _entity_src_nat.pdbx_atcc _entity_src_nat.pdbx_cellular_location _entity_src_nat.pdbx_organ _entity_src_nat.pdbx_organelle _entity_src_nat.pdbx_cell _entity_src_nat.pdbx_plasmid_name _entity_src_nat.pdbx_plasmid_details _entity_src_nat.details 1 1 sample 1 74 'Many-banded krait' 'Bungarus multicinctus' 8616 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 3 1 sample 1 213 'Norway rat' 'Rattus norvegicus' 10116 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 4 1 sample 1 219 'Norway rat' 'Rattus norvegicus' 10116 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 UNP ACHA_MOUSE P04756 ? 2 ;EHETRLVAKLFEDYSSVVRPVEDHREIVQVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIP SEKIWRPDVVLYNNADGDFAIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE SDQPDLSNFMESGEWVIKEARGWKHWVFYSCCPTTPYLDITYHFVMQRLP ; 22 2 PDB 5HBV 5HBV ? 3 ? 1 3 PDB 5HBV 5HBV ? 4 ? 1 4 UNP 3L21V_BUNMU P60616 ? 1 IVCHTTATSPISAVTCPPGENLCYRKMWCDVFCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNPHPKQRPG 22 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5HBV B 3 ? 212 ? P04756 22 ? 231 ? 2 211 2 2 5HBV C 1 ? 213 ? 5HBV 1 ? 213 ? 1 213 3 3 5HBV D 1 ? 219 ? 5HBV 1 ? 219 ? 1 219 4 4 5HBV A 1 ? 74 ? P60616 22 ? 95 ? 1 74 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 5HBV LYS B 1 ? UNP P04756 ? ? 'expression tag' 0 1 1 5HBV SER B 2 ? UNP P04756 ? ? 'expression tag' 1 2 1 5HBV GLU B 9 ? UNP P04756 VAL 28 'engineered mutation' 8 3 1 5HBV ARG B 150 ? UNP P04756 TRP 169 'engineered mutation' 149 4 1 5HBV ALA B 156 ? UNP P04756 VAL 175 'engineered mutation' 155 5 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5HBV _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.59 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 52.42 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 298 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details 'sodium cacodylate trihydrate, calcium acetate hydrate, PEG 8000' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'MARMOSAIC 300 mm CCD' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2014-02-10 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.0 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'APS BEAMLINE 23-ID-B' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 1.0 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline 23-ID-B _diffrn_source.pdbx_synchrotron_site APS # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5HBV _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 2.560 _reflns.d_resolution_low 50.000 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 26304 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 95.800 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 3.500 _reflns.pdbx_Rmerge_I_obs 0.129 _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI 11.886 _reflns.pdbx_netI_over_sigmaI 6.400 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared 1.491 _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all 0.143 _reflns.pdbx_Rpim_I_all 0.082 _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all 93174 _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # loop_ _reflns_shell.d_res_high _reflns_shell.d_res_low _reflns_shell.meanI_over_sigI_all _reflns_shell.meanI_over_sigI_obs _reflns_shell.number_measured_all _reflns_shell.number_measured_obs _reflns_shell.number_possible _reflns_shell.number_unique_all _reflns_shell.number_unique_obs _reflns_shell.percent_possible_all _reflns_shell.percent_possible_obs _reflns_shell.Rmerge_F_all _reflns_shell.Rmerge_F_obs _reflns_shell.Rmerge_I_all _reflns_shell.Rmerge_I_obs _reflns_shell.meanI_over_sigI_gt _reflns_shell.meanI_over_uI_all _reflns_shell.meanI_over_uI_gt _reflns_shell.number_measured_gt _reflns_shell.number_unique_gt _reflns_shell.percent_possible_gt _reflns_shell.Rmerge_F_gt _reflns_shell.Rmerge_I_gt _reflns_shell.pdbx_redundancy _reflns_shell.pdbx_Rsym_value _reflns_shell.pdbx_chi_squared _reflns_shell.pdbx_netI_over_sigmaI_all _reflns_shell.pdbx_netI_over_sigmaI_obs _reflns_shell.pdbx_Rrim_I_all _reflns_shell.pdbx_Rpim_I_all _reflns_shell.pdbx_rejects _reflns_shell.pdbx_ordinal _reflns_shell.pdbx_diffrn_id _reflns_shell.pdbx_CC_half _reflns_shell.pdbx_R_split 2.560 2.600 ? ? ? ? ? 600 ? 43.800 ? ? ? ? ? ? ? ? ? ? ? ? ? 2.900 ? 0.939 ? ? ? 0.666 0 1 1 0.400 ? 2.600 2.650 ? ? ? ? ? 1180 ? 87.900 ? ? ? ? ? ? ? ? ? ? ? ? ? 3.100 ? 0.904 ? ? ? 0.666 0 2 1 0.508 ? 2.650 2.700 ? ? ? ? ? 1248 ? 91.600 ? ? ? ? 0.944 ? ? ? ? ? ? ? ? 3.100 ? 0.986 ? ? ? 0.604 0 3 1 0.508 ? 2.700 2.760 ? ? ? ? ? 1294 ? 96.100 ? ? ? ? 0.865 ? ? ? ? ? ? ? ? 3.300 ? 1.000 ? ? ? 0.552 0 4 1 0.543 ? 2.760 2.820 ? ? ? ? ? 1347 ? 97.500 ? ? ? ? 0.760 ? ? ? ? ? ? ? ? 3.400 ? 1.032 ? ? 0.902 0.480 0 5 1 0.646 ? 2.820 2.880 ? ? ? ? ? 1330 ? 98.500 ? ? ? ? 0.683 ? ? ? ? ? ? ? ? 3.400 ? 1.053 ? ? 0.810 0.430 0 6 1 0.689 ? 2.880 2.960 ? ? ? ? ? 1333 ? 99.700 ? ? ? ? 0.571 ? ? ? ? ? ? ? ? 3.500 ? 1.032 ? ? 0.672 0.352 0 7 1 0.804 ? 2.960 3.040 ? ? ? ? ? 1391 ? 99.800 ? ? ? ? 0.487 ? ? ? ? ? ? ? ? 3.600 ? 1.135 ? ? 0.573 0.299 0 8 1 0.857 ? 3.040 3.120 ? ? ? ? ? 1328 ? 99.800 ? ? ? ? 0.420 ? ? ? ? ? ? ? ? 3.700 ? 1.150 ? ? 0.494 0.257 0 9 1 0.923 ? 3.120 3.230 ? ? ? ? ? 1388 ? 100.000 ? ? ? ? 0.341 ? ? ? ? ? ? ? ? 3.700 ? 1.235 ? ? 0.400 0.207 0 10 1 0.917 ? 3.230 3.340 ? ? ? ? ? 1352 ? 100.000 ? ? ? ? 0.257 ? ? ? ? ? ? ? ? 3.700 ? 1.249 ? ? 0.300 0.155 0 11 1 0.949 ? 3.340 3.470 ? ? ? ? ? 1358 ? 100.000 ? ? ? ? 0.202 ? ? ? ? ? ? ? ? 3.700 ? 1.366 ? ? 0.237 0.123 0 12 1 0.963 ? 3.470 3.630 ? ? ? ? ? 1380 ? 100.000 ? ? ? ? 0.165 ? ? ? ? ? ? ? ? 3.700 ? 1.549 ? ? 0.193 0.100 0 13 1 0.980 ? 3.630 3.820 ? ? ? ? ? 1383 ? 100.000 ? ? ? ? 0.135 ? ? ? ? ? ? ? ? 3.700 ? 1.641 ? ? 0.157 0.081 0 14 1 0.981 ? 3.820 4.060 ? ? ? ? ? 1351 ? 100.000 ? ? ? ? 0.109 ? ? ? ? ? ? ? ? 3.700 ? 1.750 ? ? 0.127 0.065 0 15 1 0.990 ? 4.060 4.380 ? ? ? ? ? 1380 ? 100.000 ? ? ? ? 0.087 ? ? ? ? ? ? ? ? 3.700 ? 1.933 ? ? 0.102 0.053 0 16 1 0.991 ? 4.380 4.820 ? ? ? ? ? 1393 ? 99.900 ? ? ? ? 0.079 ? ? ? ? ? ? ? ? 3.700 ? 2.405 ? ? 0.093 0.048 0 17 1 0.991 ? 4.820 5.510 ? ? ? ? ? 1381 ? 100.000 ? ? ? ? 0.077 ? ? ? ? ? ? ? ? 3.600 ? 2.497 ? ? 0.091 0.047 0 18 1 0.992 ? 5.510 6.940 ? ? ? ? ? 1422 ? 100.000 ? ? ? ? 0.065 ? ? ? ? ? ? ? ? 3.700 ? 1.771 ? ? 0.076 0.039 0 19 1 0.995 ? 6.940 50.000 ? ? ? ? ? 1465 ? 99.900 ? ? ? ? 0.047 ? ? ? ? ? ? ? ? 3.400 ? 2.201 ? ? 0.056 0.030 0 20 1 0.995 ? # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 5HBV _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 21877 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 50.01 _refine.ls_d_res_high 2.70 _refine.ls_percent_reflns_obs 99.51 _refine.ls_R_factor_obs 0.22938 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.22740 _refine.ls_R_factor_R_free 0.26799 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 4.9 _refine.ls_number_reflns_R_free 1117 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.931 _refine.correlation_coeff_Fo_to_Fc_free 0.902 _refine.B_iso_mean 67.870 _refine.aniso_B[1][1] 5.76 _refine.aniso_B[2][2] -1.07 _refine.aniso_B[3][3] -3.71 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.85 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free 0.376 _refine.overall_SU_ML 0.357 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 18.720 _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id 1 _refine_hist.pdbx_number_atoms_protein 5554 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 105 _refine_hist.number_atoms_solvent 46 _refine_hist.number_atoms_total 5705 _refine_hist.d_res_high 2.70 _refine_hist.d_res_low 50.01 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.007 0.020 ? 5817 'X-RAY DIFFRACTION' ? r_bond_other_d 0.001 0.020 ? 5147 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.216 1.970 ? 7954 'X-RAY DIFFRACTION' ? r_angle_other_deg 0.876 3.000 ? 12035 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.626 5.000 ? 712 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 32.967 24.353 ? 232 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 15.251 15.000 ? 917 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 17.766 15.000 ? 24 'X-RAY DIFFRACTION' ? r_chiral_restr 0.072 0.200 ? 926 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.004 0.021 ? 6303 'X-RAY DIFFRACTION' ? r_gen_planes_other 0.001 0.020 ? 1126 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 2.589 7.057 ? 2860 'X-RAY DIFFRACTION' ? r_mcbond_other 2.588 7.056 ? 2859 'X-RAY DIFFRACTION' ? r_mcangle_it 4.508 10.576 ? 3568 'X-RAY DIFFRACTION' ? r_mcangle_other 4.508 10.577 ? 3569 'X-RAY DIFFRACTION' ? r_scbond_it 2.120 7.003 ? 2957 'X-RAY DIFFRACTION' ? r_scbond_other 2.120 7.003 ? 2957 'X-RAY DIFFRACTION' ? r_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_scangle_other 3.687 10.478 ? 4387 'X-RAY DIFFRACTION' ? r_long_range_B_refined 6.562 78.561 ? 5940 'X-RAY DIFFRACTION' ? r_long_range_B_other 6.563 78.580 ? 5939 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.700 _refine_ls_shell.d_res_low 2.770 _refine_ls_shell.number_reflns_R_work 1563 _refine_ls_shell.R_factor_R_work 0.370 _refine_ls_shell.percent_reflns_obs 96.00 _refine_ls_shell.R_factor_R_free 0.325 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 67 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? # _struct.entry_id 5HBV _struct.title 'Complex structure of Fab35 and mouse nAChR alpha1' _struct.pdbx_descriptor 'Acetylcholine receptor subunit alpha 1, Fab35, Light Chain, Fab35, Heavy Chain, Alpha-bungarotoxin isoform V31' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5HBV _struct_keywords.text 'Nicotinic acetylcholine receptor alpha1, Fab35, Complex, Myasthenia gravis, TRANSPORT PROTEIN-TOXIN complex' _struct_keywords.pdbx_keywords 'TRANSPORT PROTEIN/TOXIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 5 ? G N N 6 ? H N N 7 ? I N N 7 ? J N N 7 ? K N N 7 ? L N N 7 ? M N N 7 ? N N N 8 ? O N N 8 ? P N N 8 ? Q N N 8 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 PHE A 32 ? GLY A 37 ? PHE A 32 GLY A 37 1 ? 6 HELX_P HELX_P2 AA2 SER B 2 ? GLU B 14 ? SER B 1 GLU B 13 1 ? 13 HELX_P HELX_P3 AA3 ASN B 69 ? GLY B 74 ? ASN B 68 GLY B 73 5 ? 6 HELX_P HELX_P4 AA4 GLU B 84 ? ILE B 86 ? GLU B 83 ILE B 85 5 ? 3 HELX_P HELX_P5 AA5 HIS C 79 ? LEU C 83 ? HIS C 79 LEU C 83 5 ? 5 HELX_P HELX_P6 AA6 SER C 120 ? THR C 126 ? SER C 120 THR C 126 1 ? 7 HELX_P HELX_P7 AA7 THR C 181 ? SER C 187 ? THR C 181 SER C 187 1 ? 7 HELX_P HELX_P8 AA8 SER D 61 ? LYS D 64 ? SER D 61 LYS D 64 5 ? 4 HELX_P HELX_P9 AA9 GLN D 86 ? ASP D 89 ? GLN D 86 ASP D 89 5 ? 4 HELX_P HELX_P10 AB1 LEU D 166 ? SER D 168 ? LEU D 166 SER D 168 5 ? 3 HELX_P HELX_P11 AB2 SER D 193 ? GLN D 198 ? SER D 193 GLN D 198 1 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 3 SG ? ? ? 1_555 A CYS 23 SG ? ? A CYS 3 A CYS 23 1_555 ? ? ? ? ? ? ? 2.047 ? disulf2 disulf ? ? A CYS 3 SG ? ? ? 1_555 A CYS 16 SG ? ? A CYS 3 A CYS 16 1_555 ? ? ? ? ? ? ? 2.091 ? disulf3 disulf ? ? A CYS 16 SG ? ? ? 1_555 A CYS 44 SG ? ? A CYS 16 A CYS 44 1_555 ? ? ? ? ? ? ? 2.026 ? disulf4 disulf ? ? A CYS 29 SG ? ? ? 1_555 A CYS 33 SG ? ? A CYS 29 A CYS 33 1_555 ? ? ? ? ? ? ? 2.070 ? disulf5 disulf ? ? A CYS 48 SG ? ? ? 1_555 A CYS 59 SG ? ? A CYS 48 A CYS 59 1_555 ? ? ? ? ? ? ? 2.044 ? disulf6 disulf ? ? A CYS 60 SG ? ? ? 1_555 A CYS 65 SG ? ? A CYS 60 A CYS 65 1_555 ? ? ? ? ? ? ? 2.026 ? disulf7 disulf ? ? B CYS 129 SG ? ? ? 1_555 B CYS 143 SG ? ? B CYS 128 B CYS 142 1_555 ? ? ? ? ? ? ? 2.043 ? disulf8 disulf ? ? B CYS 193 SG ? ? ? 1_555 B CYS 194 SG ? ? B CYS 192 B CYS 193 1_555 ? ? ? ? ? ? ? 2.059 ? disulf9 disulf ? ? C CYS 23 SG ? ? ? 1_555 C CYS 88 SG ? ? C CYS 23 C CYS 88 1_555 ? ? ? ? ? ? ? 2.054 ? disulf10 disulf ? ? C CYS 133 SG ? ? ? 1_555 C CYS 193 SG ? ? C CYS 133 C CYS 193 1_555 ? ? ? ? ? ? ? 2.033 ? disulf11 disulf ? ? D CYS 22 SG ? ? ? 1_555 D CYS 95 SG ? ? D CYS 22 D CYS 95 1_555 ? ? ? ? ? ? ? 2.038 ? disulf12 disulf ? ? D CYS 147 SG ? ? ? 1_555 D CYS 202 SG ? ? D CYS 147 D CYS 202 1_555 ? ? ? ? ? ? ? 2.037 ? covale1 covale one ? B ASN 142 ND2 ? ? ? 1_555 E NAG . C1 ? ? B ASN 141 B NAG 301 1_555 ? ? ? ? ? ? ? 1.440 ? covale2 covale both ? E NAG . O4 ? ? ? 1_555 F NAG . C1 ? ? B NAG 301 B NAG 302 1_555 ? ? ? ? ? ? ? 1.438 ? covale3 covale both ? F NAG . O4 ? ? ? 1_555 G BMA . C1 ? ? B NAG 302 B BMA 303 1_555 ? ? ? ? ? ? ? 1.432 ? covale4 covale one ? G BMA . O3 ? ? ? 1_555 H MAN . C1 ? ? B BMA 303 B MAN 304 1_555 ? ? ? ? ? ? ? 1.441 ? covale5 covale one ? G BMA . O6 ? ? ? 1_555 K MAN . C1 ? ? B BMA 303 B MAN 307 1_555 ? ? ? ? ? ? ? 1.436 ? covale6 covale one ? H MAN . O2 ? ? ? 1_555 I MAN . C1 ? ? B MAN 304 B MAN 305 1_555 ? ? ? ? ? ? ? 1.443 ? covale7 covale one ? I MAN . O2 ? ? ? 1_555 J MAN . C1 ? ? B MAN 305 B MAN 306 1_555 ? ? ? ? ? ? ? 1.446 ? covale8 covale one ? K MAN . O3 ? ? ? 1_555 M MAN . C1 ? ? B MAN 307 B MAN 309 1_555 ? ? ? ? ? ? ? 1.452 ? covale9 covale one ? K MAN . O6 ? ? ? 1_555 L MAN . C1 ? ? B MAN 307 B MAN 308 1_555 ? ? ? ? ? ? ? 1.445 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 SER 9 A . ? SER 9 A PRO 10 A ? PRO 10 A 1 -1.53 2 SER 7 C . ? SER 7 C PRO 8 C ? PRO 8 C 1 -10.30 3 TYR 139 C . ? TYR 139 C PRO 140 C ? PRO 140 C 1 -1.64 4 PHE 153 D . ? PHE 153 D PRO 154 D ? PRO 154 D 1 -3.18 5 GLU 155 D . ? GLU 155 D PRO 156 D ? PRO 156 D 1 1.52 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 2 ? AA2 ? 9 ? AA3 ? 8 ? AA4 ? 4 ? AA5 ? 6 ? AA6 ? 4 ? AA7 ? 4 ? AA8 ? 4 ? AA9 ? 4 ? AB1 ? 6 ? AB2 ? 4 ? AB3 ? 4 ? AB4 ? 4 ? AB5 ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA2 1 2 ? anti-parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA2 4 5 ? anti-parallel AA2 5 6 ? anti-parallel AA2 6 7 ? anti-parallel AA2 7 8 ? anti-parallel AA3 1 2 ? anti-parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA3 4 5 ? anti-parallel AA3 5 6 ? anti-parallel AA3 7 8 ? parallel AA4 1 2 ? anti-parallel AA4 2 3 ? anti-parallel AA4 3 4 ? anti-parallel AA5 1 2 ? parallel AA5 2 3 ? anti-parallel AA5 3 4 ? anti-parallel AA5 4 5 ? anti-parallel AA5 5 6 ? anti-parallel AA6 1 2 ? parallel AA6 2 3 ? anti-parallel AA6 3 4 ? anti-parallel AA7 1 2 ? anti-parallel AA7 2 3 ? anti-parallel AA7 3 4 ? anti-parallel AA8 1 2 ? anti-parallel AA8 2 3 ? anti-parallel AA8 3 4 ? anti-parallel AA9 1 2 ? anti-parallel AA9 2 3 ? anti-parallel AA9 3 4 ? anti-parallel AB1 1 2 ? parallel AB1 2 3 ? anti-parallel AB1 3 4 ? anti-parallel AB1 4 5 ? anti-parallel AB1 5 6 ? anti-parallel AB2 1 2 ? parallel AB2 2 3 ? anti-parallel AB2 3 4 ? anti-parallel AB3 1 2 ? anti-parallel AB3 2 3 ? anti-parallel AB3 3 4 ? anti-parallel AB4 1 2 ? anti-parallel AB4 2 3 ? anti-parallel AB4 3 4 ? anti-parallel AB5 1 2 ? anti-parallel AB5 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 VAL A 2 ? THR A 5 ? VAL A 2 THR A 5 AA1 2 SER A 12 ? THR A 15 ? SER A 12 THR A 15 AA2 1 GLU A 56 ? CYS A 60 ? GLU A 56 CYS A 60 AA2 2 LEU A 22 ? TRP A 28 ? LEU A 22 TRP A 28 AA2 3 VAL A 39 ? ALA A 45 ? VAL A 39 ALA A 45 AA2 4 TRP B 177 ? TYR B 191 ? TRP B 176 TYR B 190 AA2 5 CYS B 194 ? ARG B 210 ? CYS B 193 ARG B 209 AA2 6 GLU B 140 ? THR B 149 ? GLU B 139 THR B 148 AA2 7 PRO B 122 ? ILE B 131 ? PRO B 121 ILE B 130 AA2 8 ILE B 50 ? LYS B 67 ? ILE B 49 LYS B 66 AA2 9 VAL B 91 ? TYR B 94 ? VAL B 90 TYR B 93 AA3 1 LYS B 78 ? PRO B 82 ? LYS B 77 PRO B 81 AA3 2 LYS B 108 ? ASP B 112 ? LYS B 107 ASP B 111 AA3 3 THR B 114 ? TRP B 119 ? THR B 113 TRP B 118 AA3 4 ILE B 50 ? LYS B 67 ? ILE B 49 LYS B 66 AA3 5 PRO B 122 ? ILE B 131 ? PRO B 121 ILE B 130 AA3 6 GLU B 140 ? THR B 149 ? GLU B 139 THR B 148 AA3 7 VAL B 30 ? ASP B 45 ? VAL B 29 ASP B 44 AA3 8 VAL B 157 ? PRO B 161 ? VAL B 156 PRO B 160 AA4 1 ILE C 4 ? SER C 7 ? ILE C 4 SER C 7 AA4 2 VAL C 19 ? GLY C 25 ? VAL C 19 GLY C 25 AA4 3 ASP C 70 ? ILE C 75 ? ASP C 70 ILE C 75 AA4 4 PHE C 62 ? SER C 67 ? PHE C 62 SER C 67 AA5 1 LEU C 10 ? ALA C 13 ? LEU C 10 ALA C 13 AA5 2 THR C 101 ? LEU C 105 ? THR C 101 LEU C 105 AA5 3 THR C 85 ? GLN C 90 ? THR C 85 GLN C 90 AA5 4 LEU C 33 ? GLN C 38 ? LEU C 33 GLN C 38 AA5 5 LYS C 45 ? TYR C 49 ? LYS C 45 TYR C 49 AA5 6 SER C 53 ? LEU C 54 ? SER C 53 LEU C 54 AA6 1 LEU C 10 ? ALA C 13 ? LEU C 10 ALA C 13 AA6 2 THR C 101 ? LEU C 105 ? THR C 101 LEU C 105 AA6 3 THR C 85 ? GLN C 90 ? THR C 85 GLN C 90 AA6 4 THR C 96 ? PHE C 97 ? THR C 96 PHE C 97 AA7 1 THR C 113 ? PHE C 117 ? THR C 113 PHE C 117 AA7 2 ALA C 129 ? PHE C 138 ? ALA C 129 PHE C 138 AA7 3 TYR C 172 ? LEU C 180 ? TYR C 172 LEU C 180 AA7 4 VAL C 158 ? VAL C 162 ? VAL C 158 VAL C 162 AA8 1 THR C 152 ? GLU C 153 ? THR C 152 GLU C 153 AA8 2 ILE C 143 ? ILE C 149 ? ILE C 143 ILE C 149 AA8 3 TYR C 191 ? HIS C 197 ? TYR C 191 HIS C 197 AA8 4 VAL C 204 ? PHE C 208 ? VAL C 204 PHE C 208 AA9 1 GLN D 3 ? SER D 7 ? GLN D 3 SER D 7 AA9 2 LEU D 18 ? SER D 25 ? LEU D 18 SER D 25 AA9 3 GLN D 77 ? MET D 82 ? GLN D 77 MET D 82 AA9 4 LEU D 67 ? ASP D 72 ? LEU D 67 ASP D 72 AB1 1 LEU D 11 ? VAL D 12 ? LEU D 11 VAL D 12 AB1 2 LEU D 115 ? VAL D 118 ? LEU D 115 VAL D 118 AB1 3 GLY D 91 ? ILE D 101 ? GLY D 91 ILE D 101 AB1 4 SER D 33 ? PRO D 40 ? SER D 33 PRO D 40 AB1 5 GLU D 46 ? MET D 51 ? GLU D 46 MET D 51 AB1 6 THR D 57 ? TYR D 59 ? THR D 57 TYR D 59 AB2 1 LEU D 11 ? VAL D 12 ? LEU D 11 VAL D 12 AB2 2 LEU D 115 ? VAL D 118 ? LEU D 115 VAL D 118 AB2 3 GLY D 91 ? ILE D 101 ? GLY D 91 ILE D 101 AB2 4 ILE D 104 ? TRP D 110 ? ILE D 104 TRP D 110 AB3 1 SER D 127 ? LEU D 131 ? SER D 127 LEU D 131 AB3 2 VAL D 143 ? TYR D 152 ? VAL D 143 TYR D 152 AB3 3 TYR D 182 ? VAL D 190 ? TYR D 182 VAL D 190 AB3 4 VAL D 170 ? THR D 172 ? VAL D 170 THR D 172 AB4 1 SER D 127 ? LEU D 131 ? SER D 127 LEU D 131 AB4 2 VAL D 143 ? TYR D 152 ? VAL D 143 TYR D 152 AB4 3 TYR D 182 ? VAL D 190 ? TYR D 182 VAL D 190 AB4 4 VAL D 176 ? LEU D 177 ? VAL D 176 LEU D 177 AB5 1 THR D 158 ? TRP D 161 ? THR D 158 TRP D 161 AB5 2 THR D 201 ? HIS D 206 ? THR D 201 HIS D 206 AB5 3 HIS D 211 ? ARG D 216 ? HIS D 211 ARG D 216 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N CYS A 3 ? N CYS A 3 O VAL A 14 ? O VAL A 14 AA2 1 2 O CYS A 60 ? O CYS A 60 N CYS A 23 ? N CYS A 23 AA2 2 3 N TRP A 28 ? N TRP A 28 O VAL A 39 ? O VAL A 39 AA2 3 4 N VAL A 40 ? N VAL A 40 O PHE B 190 ? O PHE B 189 AA2 4 5 N HIS B 187 ? N HIS B 186 O ASP B 201 ? O ASP B 200 AA2 5 6 O TYR B 204 ? O TYR B 203 N MET B 145 ? N MET B 144 AA2 6 7 O ASN B 142 ? O ASN B 141 N GLU B 130 ? N GLU B 129 AA2 7 8 O PHE B 125 ? O PHE B 124 N THR B 53 ? N THR B 52 AA3 1 2 N ILE B 79 ? N ILE B 78 O LEU B 111 ? O LEU B 110 AA3 2 3 N LEU B 110 ? N LEU B 109 O THR B 118 ? O THR B 117 AA3 3 4 O TRP B 119 ? O TRP B 118 N GLN B 59 ? N GLN B 58 AA3 4 5 N THR B 53 ? N THR B 52 O PHE B 125 ? O PHE B 124 AA3 5 6 N GLU B 130 ? N GLU B 129 O ASN B 142 ? O ASN B 141 AA3 7 8 N VAL B 32 ? N VAL B 31 O ASN B 160 ? O ASN B 159 AA4 1 2 N SER C 7 ? N SER C 7 O THR C 22 ? O THR C 22 AA4 2 3 N LEU C 21 ? N LEU C 21 O LEU C 73 ? O LEU C 73 AA4 3 4 O THR C 72 ? O THR C 72 N SER C 65 ? N SER C 65 AA5 1 2 N LEU C 11 ? N LEU C 11 O GLU C 104 ? O GLU C 104 AA5 2 3 O THR C 101 ? O THR C 101 N TYR C 86 ? N TYR C 86 AA5 3 4 O TYR C 89 ? O TYR C 89 N ALA C 34 ? N ALA C 34 AA5 4 5 N GLN C 37 ? N GLN C 37 O LYS C 45 ? O LYS C 45 AA5 5 6 N TYR C 49 ? N TYR C 49 O SER C 53 ? O SER C 53 AA6 1 2 N LEU C 11 ? N LEU C 11 O GLU C 104 ? O GLU C 104 AA6 2 3 O THR C 101 ? O THR C 101 N TYR C 86 ? N TYR C 86 AA6 3 4 N GLN C 90 ? N GLN C 90 O THR C 96 ? O THR C 96 AA7 1 2 N THR C 113 ? N THR C 113 O ASN C 136 ? O ASN C 136 AA7 2 3 N ALA C 129 ? N ALA C 129 O LEU C 180 ? O LEU C 180 AA7 3 4 O SER C 175 ? O SER C 175 N SER C 161 ? N SER C 161 AA8 1 2 O THR C 152 ? O THR C 152 N ILE C 149 ? N ILE C 149 AA8 2 3 N LYS C 146 ? N LYS C 146 O GLU C 194 ? O GLU C 194 AA8 3 4 N CYS C 193 ? N CYS C 193 O LYS C 206 ? O LYS C 206 AA9 1 2 N GLN D 5 ? N GLN D 5 O THR D 23 ? O THR D 23 AA9 2 3 N CYS D 22 ? N CYS D 22 O VAL D 78 ? O VAL D 78 AA9 3 4 O GLN D 77 ? O GLN D 77 N ASP D 72 ? N ASP D 72 AB1 1 2 N VAL D 12 ? N VAL D 12 O THR D 117 ? O THR D 117 AB1 2 3 O VAL D 116 ? O VAL D 116 N GLY D 91 ? N GLY D 91 AB1 3 4 O TYR D 94 ? O TYR D 94 N LEU D 37 ? N LEU D 37 AB1 4 5 N VAL D 34 ? N VAL D 34 O MET D 51 ? O MET D 51 AB1 5 6 N ARG D 50 ? N ARG D 50 O VAL D 58 ? O VAL D 58 AB2 1 2 N VAL D 12 ? N VAL D 12 O THR D 117 ? O THR D 117 AB2 2 3 O VAL D 116 ? O VAL D 116 N GLY D 91 ? N GLY D 91 AB2 3 4 N ILE D 101 ? N ILE D 101 O ILE D 104 ? O ILE D 104 AB3 1 2 N SER D 127 ? N SER D 127 O LYS D 150 ? O LYS D 150 AB3 2 3 N VAL D 149 ? N VAL D 149 O LEU D 184 ? O LEU D 184 AB3 3 4 O SER D 187 ? O SER D 187 N HIS D 171 ? N HIS D 171 AB4 1 2 N SER D 127 ? N SER D 127 O LYS D 150 ? O LYS D 150 AB4 2 3 N VAL D 149 ? N VAL D 149 O LEU D 184 ? O LEU D 184 AB4 3 4 O THR D 183 ? O THR D 183 N VAL D 176 ? N VAL D 176 AB5 1 2 N THR D 160 ? N THR D 160 O ASN D 203 ? O ASN D 203 AB5 2 3 N HIS D 206 ? N HIS D 206 O HIS D 211 ? O HIS D 211 # _struct_site.id AC1 _struct_site.pdbx_evidence_code Software _struct_site.pdbx_auth_asym_id B _struct_site.pdbx_auth_comp_id ASN _struct_site.pdbx_auth_seq_id 141 _struct_site.pdbx_auth_ins_code ? _struct_site.pdbx_num_residues 12 _struct_site.details 'binding site for Poly-Saccharide residues NAG B 301 through MAN B 309 bound to ASN B 141' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 12 THR A 6 ? THR A 6 . ? 1_555 ? 2 AC1 12 ALA A 7 ? ALA A 7 . ? 1_555 ? 3 AC1 12 THR A 8 ? THR A 8 . ? 1_555 ? 4 AC1 12 SER A 9 ? SER A 9 . ? 1_555 ? 5 AC1 12 LEU A 42 ? LEU A 42 . ? 1_555 ? 6 AC1 12 ASN B 142 ? ASN B 141 . ? 1_555 ? 7 AC1 12 TRP B 185 ? TRP B 184 . ? 1_555 ? 8 AC1 12 LYS B 186 ? LYS B 185 . ? 1_555 ? 9 AC1 12 HIS B 187 ? HIS B 186 . ? 1_555 ? 10 AC1 12 TRP B 188 ? TRP B 187 . ? 1_555 ? 11 AC1 12 THR B 203 ? THR B 202 . ? 1_555 ? 12 AC1 12 HOH O . ? HOH B 413 . ? 1_555 ? # _atom_sites.entry_id 5HBV _atom_sites.fract_transf_matrix[1][1] 0.006254 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.003112 _atom_sites.fract_transf_matrix[2][1] -0.000000 _atom_sites.fract_transf_matrix[2][2] 0.023796 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] -0.000000 _atom_sites.fract_transf_matrix[3][3] 0.008119 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ILE A 1 1 ? -5.737 -25.535 -11.850 1.00 53.53 ? 1 ILE A N 1 ATOM 2 C CA . ILE A 1 1 ? -4.735 -26.631 -11.689 1.00 53.14 ? 1 ILE A CA 1 ATOM 3 C C . ILE A 1 1 ? -3.922 -26.414 -10.421 1.00 52.86 ? 1 ILE A C 1 ATOM 4 O O . ILE A 1 1 ? -3.626 -25.281 -10.072 1.00 51.61 ? 1 ILE A O 1 ATOM 5 C CB . ILE A 1 1 ? -3.793 -26.722 -12.914 1.00 53.92 ? 1 ILE A CB 1 ATOM 6 C CG1 . ILE A 1 1 ? -2.907 -27.974 -12.849 1.00 53.22 ? 1 ILE A CG1 1 ATOM 7 C CG2 . ILE A 1 1 ? -2.929 -25.476 -13.049 1.00 55.67 ? 1 ILE A CG2 1 ATOM 8 C CD1 . ILE A 1 1 ? -2.079 -28.202 -14.098 1.00 52.84 ? 1 ILE A CD1 1 ATOM 9 N N . VAL A 1 2 ? -3.567 -27.508 -9.749 1.00 55.10 ? 2 VAL A N 1 ATOM 10 C CA . VAL A 1 2 ? -2.701 -27.479 -8.564 1.00 55.73 ? 2 VAL A CA 1 ATOM 11 C C . VAL A 1 2 ? -1.263 -27.851 -8.959 1.00 56.72 ? 2 VAL A C 1 ATOM 12 O O . VAL A 1 2 ? -1.056 -28.830 -9.680 1.00 53.72 ? 2 VAL A O 1 ATOM 13 C CB . VAL A 1 2 ? -3.224 -28.439 -7.475 1.00 55.29 ? 2 VAL A CB 1 ATOM 14 C CG1 . VAL A 1 2 ? -2.328 -28.413 -6.236 1.00 54.48 ? 2 VAL A CG1 1 ATOM 15 C CG2 . VAL A 1 2 ? -4.660 -28.077 -7.111 1.00 55.96 ? 2 VAL A CG2 1 ATOM 16 N N . CYS A 1 3 ? -0.290 -27.071 -8.472 1.00 58.39 ? 3 CYS A N 1 ATOM 17 C CA . CYS A 1 3 ? 1.142 -27.243 -8.790 1.00 59.23 ? 3 CYS A CA 1 ATOM 18 C C . CYS A 1 3 ? 1.985 -27.319 -7.522 1.00 56.03 ? 3 CYS A C 1 ATOM 19 O O . CYS A 1 3 ? 1.697 -26.619 -6.555 1.00 57.01 ? 3 CYS A O 1 ATOM 20 C CB . CYS A 1 3 ? 1.651 -26.046 -9.606 1.00 63.24 ? 3 CYS A CB 1 ATOM 21 S SG . CYS A 1 3 ? 0.625 -25.552 -11.019 1.00 72.19 ? 3 CYS A SG 1 ATOM 22 N N . HIS A 1 4 ? 3.034 -28.140 -7.527 1.00 52.94 ? 4 HIS A N 1 ATOM 23 C CA . HIS A 1 4 ? 4.053 -28.065 -6.470 1.00 49.93 ? 4 HIS A CA 1 ATOM 24 C C . HIS A 1 4 ? 4.830 -26.775 -6.657 1.00 46.99 ? 4 HIS A C 1 ATOM 25 O O . HIS A 1 4 ? 4.993 -26.315 -7.778 1.00 47.38 ? 4 HIS A O 1 ATOM 26 C CB . HIS A 1 4 ? 5.020 -29.247 -6.500 1.00 50.83 ? 4 HIS A CB 1 ATOM 27 C CG . HIS A 1 4 ? 4.417 -30.538 -6.042 1.00 51.74 ? 4 HIS A CG 1 ATOM 28 N ND1 . HIS A 1 4 ? 4.189 -31.596 -6.895 1.00 50.94 ? 4 HIS A ND1 1 ATOM 29 C CD2 . HIS A 1 4 ? 4.000 -30.942 -4.819 1.00 51.26 ? 4 HIS A CD2 1 ATOM 30 C CE1 . HIS A 1 4 ? 3.656 -32.596 -6.216 1.00 51.83 ? 4 HIS A CE1 1 ATOM 31 N NE2 . HIS A 1 4 ? 3.529 -32.225 -4.955 1.00 49.89 ? 4 HIS A NE2 1 ATOM 32 N N . THR A 1 5 ? 5.305 -26.196 -5.560 1.00 46.64 ? 5 THR A N 1 ATOM 33 C CA . THR A 1 5 ? 6.011 -24.917 -5.611 1.00 45.00 ? 5 THR A CA 1 ATOM 34 C C . THR A 1 5 ? 7.178 -24.855 -4.618 1.00 45.80 ? 5 THR A C 1 ATOM 35 O O . THR A 1 5 ? 7.031 -25.195 -3.447 1.00 45.86 ? 5 THR A O 1 ATOM 36 C CB . THR A 1 5 ? 5.047 -23.726 -5.390 1.00 43.83 ? 5 THR A CB 1 ATOM 37 O OG1 . THR A 1 5 ? 5.751 -22.495 -5.562 1.00 44.17 ? 5 THR A OG1 1 ATOM 38 C CG2 . THR A 1 5 ? 4.428 -23.732 -4.002 1.00 43.95 ? 5 THR A CG2 1 ATOM 39 N N . THR A 1 6 ? 8.337 -24.417 -5.109 1.00 46.86 ? 6 THR A N 1 ATOM 40 C CA . THR A 1 6 ? 9.478 -24.085 -4.257 1.00 46.35 ? 6 THR A CA 1 ATOM 41 C C . THR A 1 6 ? 9.427 -22.624 -3.775 1.00 45.19 ? 6 THR A C 1 ATOM 42 O O . THR A 1 6 ? 10.376 -22.151 -3.158 1.00 48.48 ? 6 THR A O 1 ATOM 43 C CB . THR A 1 6 ? 10.821 -24.339 -4.979 1.00 46.49 ? 6 THR A CB 1 ATOM 44 O OG1 . THR A 1 6 ? 10.875 -23.569 -6.188 1.00 46.35 ? 6 THR A OG1 1 ATOM 45 C CG2 . THR A 1 6 ? 10.993 -25.826 -5.294 1.00 46.12 ? 6 THR A CG2 1 ATOM 46 N N . ALA A 1 7 ? 8.340 -21.905 -4.053 1.00 42.73 ? 7 ALA A N 1 ATOM 47 C CA . ALA A 1 7 ? 8.104 -20.613 -3.416 1.00 44.62 ? 7 ALA A CA 1 ATOM 48 C C . ALA A 1 7 ? 8.045 -20.749 -1.899 1.00 45.45 ? 7 ALA A C 1 ATOM 49 O O . ALA A 1 7 ? 8.533 -19.885 -1.187 1.00 49.56 ? 7 ALA A O 1 ATOM 50 C CB . ALA A 1 7 ? 6.820 -19.984 -3.932 1.00 45.62 ? 7 ALA A CB 1 ATOM 51 N N . THR A 1 8 ? 7.452 -21.839 -1.419 1.00 45.33 ? 8 THR A N 1 ATOM 52 C CA . THR A 1 8 ? 7.338 -22.123 0.010 1.00 44.32 ? 8 THR A CA 1 ATOM 53 C C . THR A 1 8 ? 8.447 -23.053 0.496 1.00 43.63 ? 8 THR A C 1 ATOM 54 O O . THR A 1 8 ? 9.209 -23.589 -0.303 1.00 43.55 ? 8 THR A O 1 ATOM 55 C CB . THR A 1 8 ? 5.983 -22.786 0.303 1.00 43.96 ? 8 THR A CB 1 ATOM 56 O OG1 . THR A 1 8 ? 5.846 -23.970 -0.501 1.00 42.95 ? 8 THR A OG1 1 ATOM 57 C CG2 . THR A 1 8 ? 4.850 -21.818 -0.009 1.00 43.38 ? 8 THR A CG2 1 ATOM 58 N N . SER A 1 9 ? 8.521 -23.227 1.816 1.00 44.49 ? 9 SER A N 1 ATOM 59 C CA . SER A 1 9 ? 9.431 -24.186 2.456 1.00 44.00 ? 9 SER A CA 1 ATOM 60 C C . SER A 1 9 ? 8.786 -24.803 3.720 1.00 44.43 ? 9 SER A C 1 ATOM 61 O O . SER A 1 9 ? 8.452 -24.071 4.655 1.00 43.49 ? 9 SER A O 1 ATOM 62 C CB . SER A 1 9 ? 10.740 -23.524 2.839 1.00 43.80 ? 9 SER A CB 1 ATOM 63 O OG . SER A 1 9 ? 11.577 -24.463 3.484 1.00 44.79 ? 9 SER A OG 1 ATOM 64 N N . PRO A 1 10 ? 8.594 -26.143 3.746 1.00 43.14 ? 10 PRO A N 1 ATOM 65 C CA . PRO A 1 10 ? 8.906 -27.095 2.678 1.00 42.49 ? 10 PRO A CA 1 ATOM 66 C C . PRO A 1 10 ? 8.045 -26.888 1.426 1.00 42.87 ? 10 PRO A C 1 ATOM 67 O O . PRO A 1 10 ? 7.152 -26.034 1.405 1.00 42.71 ? 10 PRO A O 1 ATOM 68 C CB . PRO A 1 10 ? 8.620 -28.449 3.325 1.00 42.59 ? 10 PRO A CB 1 ATOM 69 C CG . PRO A 1 10 ? 7.582 -28.165 4.349 1.00 42.32 ? 10 PRO A CG 1 ATOM 70 C CD . PRO A 1 10 ? 7.944 -26.811 4.888 1.00 42.89 ? 10 PRO A CD 1 ATOM 71 N N . ILE A 1 11 ? 8.340 -27.669 0.393 1.00 44.49 ? 11 ILE A N 1 ATOM 72 C CA . ILE A 1 11 ? 7.650 -27.584 -0.899 1.00 43.62 ? 11 ILE A CA 1 ATOM 73 C C . ILE A 1 11 ? 6.181 -27.926 -0.670 1.00 43.36 ? 11 ILE A C 1 ATOM 74 O O . ILE A 1 11 ? 5.873 -28.801 0.134 1.00 45.35 ? 11 ILE A O 1 ATOM 75 C CB . ILE A 1 11 ? 8.284 -28.544 -1.937 1.00 43.07 ? 11 ILE A CB 1 ATOM 76 C CG1 . ILE A 1 11 ? 9.733 -28.132 -2.240 1.00 43.25 ? 11 ILE A CG1 1 ATOM 77 C CG2 . ILE A 1 11 ? 7.475 -28.584 -3.230 1.00 44.00 ? 11 ILE A CG2 1 ATOM 78 C CD1 . ILE A 1 11 ? 10.610 -29.261 -2.741 1.00 42.39 ? 11 ILE A CD1 1 ATOM 79 N N . SER A 1 12 ? 5.295 -27.214 -1.360 1.00 44.72 ? 12 SER A N 1 ATOM 80 C CA . SER A 1 12 ? 3.851 -27.292 -1.139 1.00 45.74 ? 12 SER A CA 1 ATOM 81 C C . SER A 1 12 ? 3.094 -27.382 -2.445 1.00 44.12 ? 12 SER A C 1 ATOM 82 O O . SER A 1 12 ? 3.586 -26.956 -3.476 1.00 41.97 ? 12 SER A O 1 ATOM 83 C CB . SER A 1 12 ? 3.370 -26.041 -0.418 1.00 47.58 ? 12 SER A CB 1 ATOM 84 O OG . SER A 1 12 ? 4.240 -25.723 0.644 1.00 55.54 ? 12 SER A OG 1 ATOM 85 N N . ALA A 1 13 ? 1.882 -27.924 -2.373 1.00 44.80 ? 13 ALA A N 1 ATOM 86 C CA . ALA A 1 13 ? 0.943 -27.914 -3.487 1.00 44.93 ? 13 ALA A CA 1 ATOM 87 C C . ALA A 1 13 ? 0.088 -26.658 -3.368 1.00 45.12 ? 13 ALA A C 1 ATOM 88 O O . ALA A 1 13 ? -0.514 -26.408 -2.320 1.00 46.18 ? 13 ALA A O 1 ATOM 89 C CB . ALA A 1 13 ? 0.073 -29.160 -3.465 1.00 44.36 ? 13 ALA A CB 1 ATOM 90 N N . VAL A 1 14 ? 0.039 -25.880 -4.444 1.00 45.92 ? 14 VAL A N 1 ATOM 91 C CA . VAL A 1 14 ? -0.664 -24.600 -4.473 1.00 48.66 ? 14 VAL A CA 1 ATOM 92 C C . VAL A 1 14 ? -1.588 -24.546 -5.699 1.00 50.18 ? 14 VAL A C 1 ATOM 93 O O . VAL A 1 14 ? -1.246 -25.082 -6.759 1.00 50.12 ? 14 VAL A O 1 ATOM 94 C CB . VAL A 1 14 ? 0.370 -23.443 -4.447 1.00 48.54 ? 14 VAL A CB 1 ATOM 95 C CG1 . VAL A 1 14 ? -0.176 -22.142 -5.031 1.00 50.34 ? 14 VAL A CG1 1 ATOM 96 C CG2 . VAL A 1 14 ? 0.860 -23.226 -3.020 1.00 47.50 ? 14 VAL A CG2 1 ATOM 97 N N . THR A 1 15 ? -2.757 -23.914 -5.540 1.00 51.17 ? 15 THR A N 1 ATOM 98 C CA . THR A 1 15 ? -3.656 -23.666 -6.668 1.00 53.40 ? 15 THR A CA 1 ATOM 99 C C . THR A 1 15 ? -3.016 -22.608 -7.548 1.00 54.11 ? 15 THR A C 1 ATOM 100 O O . THR A 1 15 ? -2.862 -21.460 -7.138 1.00 51.20 ? 15 THR A O 1 ATOM 101 C CB . THR A 1 15 ? -5.059 -23.191 -6.239 1.00 53.86 ? 15 THR A CB 1 ATOM 102 O OG1 . THR A 1 15 ? -5.720 -24.229 -5.509 1.00 56.45 ? 15 THR A OG1 1 ATOM 103 C CG2 . THR A 1 15 ? -5.913 -22.845 -7.455 1.00 53.65 ? 15 THR A CG2 1 ATOM 104 N N . CYS A 1 16 ? -2.623 -23.023 -8.748 1.00 61.39 ? 16 CYS A N 1 ATOM 105 C CA . CYS A 1 16 ? -1.981 -22.133 -9.708 1.00 66.21 ? 16 CYS A CA 1 ATOM 106 C C . CYS A 1 16 ? -3.021 -21.041 -10.112 1.00 67.28 ? 16 CYS A C 1 ATOM 107 O O . CYS A 1 16 ? -4.176 -21.377 -10.394 1.00 63.58 ? 16 CYS A O 1 ATOM 108 C CB . CYS A 1 16 ? -1.367 -22.942 -10.898 1.00 66.45 ? 16 CYS A CB 1 ATOM 109 S SG . CYS A 1 16 ? 0.357 -23.515 -10.630 1.00 74.33 ? 16 CYS A SG 1 ATOM 110 N N . PRO A 1 17 ? -2.634 -19.733 -10.071 1.00 70.74 ? 17 PRO A N 1 ATOM 111 C CA . PRO A 1 17 ? -3.603 -18.627 -10.297 1.00 72.99 ? 17 PRO A CA 1 ATOM 112 C C . PRO A 1 17 ? -4.208 -18.546 -11.719 1.00 74.46 ? 17 PRO A C 1 ATOM 113 O O . PRO A 1 17 ? -3.725 -19.223 -12.625 1.00 74.12 ? 17 PRO A O 1 ATOM 114 C CB . PRO A 1 17 ? -2.776 -17.358 -10.003 1.00 71.76 ? 17 PRO A CB 1 ATOM 115 C CG . PRO A 1 17 ? -1.512 -17.816 -9.372 1.00 70.50 ? 17 PRO A CG 1 ATOM 116 C CD . PRO A 1 17 ? -1.270 -19.201 -9.875 1.00 70.42 ? 17 PRO A CD 1 ATOM 117 N N . PRO A 1 18 ? -5.247 -17.701 -11.918 1.00 76.27 ? 18 PRO A N 1 ATOM 118 C CA . PRO A 1 18 ? -5.948 -17.691 -13.214 1.00 76.54 ? 18 PRO A CA 1 ATOM 119 C C . PRO A 1 18 ? -5.082 -17.112 -14.329 1.00 78.89 ? 18 PRO A C 1 ATOM 120 O O . PRO A 1 18 ? -4.448 -16.071 -14.137 1.00 81.71 ? 18 PRO A O 1 ATOM 121 C CB . PRO A 1 18 ? -7.179 -16.808 -12.963 1.00 76.49 ? 18 PRO A CB 1 ATOM 122 C CG . PRO A 1 18 ? -6.968 -16.145 -11.638 1.00 77.35 ? 18 PRO A CG 1 ATOM 123 C CD . PRO A 1 18 ? -5.649 -16.567 -11.067 1.00 75.82 ? 18 PRO A CD 1 ATOM 124 N N . GLY A 1 19 ? -5.058 -17.794 -15.474 1.00 78.78 ? 19 GLY A N 1 ATOM 125 C CA . GLY A 1 19 ? -4.133 -17.479 -16.568 1.00 77.48 ? 19 GLY A CA 1 ATOM 126 C C . GLY A 1 19 ? -2.983 -18.466 -16.568 1.00 76.85 ? 19 GLY A C 1 ATOM 127 O O . GLY A 1 19 ? -2.649 -19.042 -17.603 1.00 78.27 ? 19 GLY A O 1 ATOM 128 N N . GLU A 1 20 ? -2.381 -18.651 -15.394 1.00 77.77 ? 20 GLU A N 1 ATOM 129 C CA . GLU A 1 20 ? -1.313 -19.626 -15.187 1.00 75.84 ? 20 GLU A CA 1 ATOM 130 C C . GLU A 1 20 ? -1.911 -21.003 -14.894 1.00 73.45 ? 20 GLU A C 1 ATOM 131 O O . GLU A 1 20 ? -2.296 -21.302 -13.765 1.00 77.03 ? 20 GLU A O 1 ATOM 132 C CB . GLU A 1 20 ? -0.376 -19.162 -14.059 1.00 75.31 ? 20 GLU A CB 1 ATOM 133 C CG . GLU A 1 20 ? 0.275 -17.806 -14.332 1.00 74.00 ? 20 GLU A CG 1 ATOM 134 C CD . GLU A 1 20 ? 1.216 -17.344 -13.236 1.00 73.90 ? 20 GLU A CD 1 ATOM 135 O OE1 . GLU A 1 20 ? 1.757 -16.228 -13.358 1.00 72.66 ? 20 GLU A OE1 1 ATOM 136 O OE2 . GLU A 1 20 ? 1.426 -18.085 -12.254 1.00 77.26 ? 20 GLU A OE2 1 ATOM 137 N N . ASN A 1 21 ? -1.987 -21.836 -15.926 1.00 70.59 ? 21 ASN A N 1 ATOM 138 C CA . ASN A 1 21 ? -2.589 -23.167 -15.812 1.00 69.84 ? 21 ASN A CA 1 ATOM 139 C C . ASN A 1 21 ? -1.667 -24.276 -16.355 1.00 67.27 ? 21 ASN A C 1 ATOM 140 O O . ASN A 1 21 ? -2.133 -25.313 -16.839 1.00 64.58 ? 21 ASN A O 1 ATOM 141 C CB . ASN A 1 21 ? -3.990 -23.184 -16.456 1.00 71.29 ? 21 ASN A CB 1 ATOM 142 C CG . ASN A 1 21 ? -4.046 -22.405 -17.751 1.00 71.36 ? 21 ASN A CG 1 ATOM 143 O OD1 . ASN A 1 21 ? -3.271 -22.661 -18.675 1.00 72.36 ? 21 ASN A OD1 1 ATOM 144 N ND2 . ASN A 1 21 ? -4.950 -21.432 -17.816 1.00 69.06 ? 21 ASN A ND2 1 ATOM 145 N N . LEU A 1 22 ? -0.356 -24.044 -16.251 1.00 66.05 ? 22 LEU A N 1 ATOM 146 C CA . LEU A 1 22 ? 0.655 -25.092 -16.392 1.00 66.80 ? 22 LEU A CA 1 ATOM 147 C C . LEU A 1 22 ? 1.490 -25.127 -15.121 1.00 65.18 ? 22 LEU A C 1 ATOM 148 O O . LEU A 1 22 ? 1.736 -24.083 -14.506 1.00 66.87 ? 22 LEU A O 1 ATOM 149 C CB . LEU A 1 22 ? 1.581 -24.820 -17.576 1.00 67.88 ? 22 LEU A CB 1 ATOM 150 C CG . LEU A 1 22 ? 0.943 -24.662 -18.952 1.00 68.37 ? 22 LEU A CG 1 ATOM 151 C CD1 . LEU A 1 22 ? 2.005 -24.240 -19.958 1.00 69.41 ? 22 LEU A CD1 1 ATOM 152 C CD2 . LEU A 1 22 ? 0.264 -25.953 -19.387 1.00 66.90 ? 22 LEU A CD2 1 ATOM 153 N N . CYS A 1 23 ? 1.915 -26.327 -14.734 1.00 61.62 ? 23 CYS A N 1 ATOM 154 C CA . CYS A 1 23 ? 2.882 -26.501 -13.655 1.00 62.13 ? 23 CYS A CA 1 ATOM 155 C C . CYS A 1 23 ? 4.206 -26.904 -14.301 1.00 60.57 ? 23 CYS A C 1 ATOM 156 O O . CYS A 1 23 ? 4.208 -27.682 -15.260 1.00 64.54 ? 23 CYS A O 1 ATOM 157 C CB . CYS A 1 23 ? 2.395 -27.545 -12.644 1.00 61.85 ? 23 CYS A CB 1 ATOM 158 S SG . CYS A 1 23 ? 0.685 -27.302 -12.080 1.00 64.29 ? 23 CYS A SG 1 ATOM 159 N N . TYR A 1 24 ? 5.315 -26.353 -13.797 1.00 56.80 ? 24 TYR A N 1 ATOM 160 C CA . TYR A 1 24 ? 6.642 -26.537 -14.404 1.00 54.99 ? 24 TYR A CA 1 ATOM 161 C C . TYR A 1 24 ? 7.698 -27.029 -13.396 1.00 54.89 ? 24 TYR A C 1 ATOM 162 O O . TYR A 1 24 ? 7.492 -26.965 -12.185 1.00 54.79 ? 24 TYR A O 1 ATOM 163 C CB . TYR A 1 24 ? 7.105 -25.229 -15.090 1.00 53.79 ? 24 TYR A CB 1 ATOM 164 C CG . TYR A 1 24 ? 7.671 -24.173 -14.156 1.00 53.24 ? 24 TYR A CG 1 ATOM 165 C CD1 . TYR A 1 24 ? 9.008 -24.206 -13.768 1.00 54.64 ? 24 TYR A CD1 1 ATOM 166 C CD2 . TYR A 1 24 ? 6.879 -23.142 -13.666 1.00 53.61 ? 24 TYR A CD2 1 ATOM 167 C CE1 . TYR A 1 24 ? 9.534 -23.255 -12.904 1.00 56.10 ? 24 TYR A CE1 1 ATOM 168 C CE2 . TYR A 1 24 ? 7.397 -22.183 -12.799 1.00 53.69 ? 24 TYR A CE2 1 ATOM 169 C CZ . TYR A 1 24 ? 8.726 -22.243 -12.420 1.00 54.37 ? 24 TYR A CZ 1 ATOM 170 O OH . TYR A 1 24 ? 9.263 -21.304 -11.566 1.00 52.15 ? 24 TYR A OH 1 ATOM 171 N N . ARG A 1 25 ? 8.818 -27.523 -13.929 1.00 55.29 ? 25 ARG A N 1 ATOM 172 C CA . ARG A 1 25 ? 10.020 -27.852 -13.157 1.00 54.92 ? 25 ARG A CA 1 ATOM 173 C C . ARG A 1 25 ? 11.280 -27.465 -13.948 1.00 54.44 ? 25 ARG A C 1 ATOM 174 O O . ARG A 1 25 ? 11.520 -28.015 -15.026 1.00 53.29 ? 25 ARG A O 1 ATOM 175 C CB . ARG A 1 25 ? 10.063 -29.345 -12.843 1.00 56.62 ? 25 ARG A CB 1 ATOM 176 C CG . ARG A 1 25 ? 11.301 -29.788 -12.059 1.00 60.24 ? 25 ARG A CG 1 ATOM 177 C CD . ARG A 1 25 ? 11.816 -31.136 -12.521 1.00 63.37 ? 25 ARG A CD 1 ATOM 178 N NE . ARG A 1 25 ? 10.918 -32.213 -12.109 1.00 64.83 ? 25 ARG A NE 1 ATOM 179 C CZ . ARG A 1 25 ? 10.736 -33.360 -12.763 1.00 68.36 ? 25 ARG A CZ 1 ATOM 180 N NH1 . ARG A 1 25 ? 11.379 -33.635 -13.901 1.00 68.98 ? 25 ARG A NH1 1 ATOM 181 N NH2 . ARG A 1 25 ? 9.879 -34.250 -12.274 1.00 72.38 ? 25 ARG A NH2 1 ATOM 182 N N . LYS A 1 26 ? 12.075 -26.543 -13.399 1.00 54.01 ? 26 LYS A N 1 ATOM 183 C CA . LYS A 1 26 ? 13.366 -26.133 -13.972 1.00 54.23 ? 26 LYS A CA 1 ATOM 184 C C . LYS A 1 26 ? 14.499 -26.655 -13.120 1.00 50.86 ? 26 LYS A C 1 ATOM 185 O O . LYS A 1 26 ? 14.461 -26.500 -11.904 1.00 49.91 ? 26 LYS A O 1 ATOM 186 C CB . LYS A 1 26 ? 13.508 -24.612 -13.970 1.00 57.73 ? 26 LYS A CB 1 ATOM 187 C CG . LYS A 1 26 ? 12.622 -23.856 -14.936 1.00 60.42 ? 26 LYS A CG 1 ATOM 188 C CD . LYS A 1 26 ? 12.756 -22.355 -14.727 1.00 63.85 ? 26 LYS A CD 1 ATOM 189 C CE . LYS A 1 26 ? 14.075 -21.814 -15.260 1.00 66.70 ? 26 LYS A CE 1 ATOM 190 N NZ . LYS A 1 26 ? 14.241 -20.366 -14.945 1.00 69.40 ? 26 LYS A NZ 1 ATOM 191 N N . MET A 1 27 ? 15.526 -27.215 -13.752 1.00 50.44 ? 27 MET A N 1 ATOM 192 C CA . MET A 1 27 ? 16.715 -27.689 -13.031 1.00 50.91 ? 27 MET A CA 1 ATOM 193 C C . MET A 1 27 ? 18.010 -27.231 -13.690 1.00 49.62 ? 27 MET A C 1 ATOM 194 O O . MET A 1 27 ? 18.101 -27.166 -14.912 1.00 48.45 ? 27 MET A O 1 ATOM 195 C CB . MET A 1 27 ? 16.700 -29.211 -12.914 1.00 51.29 ? 27 MET A CB 1 ATOM 196 C CG . MET A 1 27 ? 15.549 -29.730 -12.075 1.00 52.08 ? 27 MET A CG 1 ATOM 197 S SD . MET A 1 27 ? 15.643 -31.504 -11.794 1.00 53.48 ? 27 MET A SD 1 ATOM 198 C CE . MET A 1 27 ? 15.342 -32.136 -13.441 1.00 55.64 ? 27 MET A CE 1 ATOM 199 N N . TRP A 1 28 ? 19.007 -26.911 -12.868 1.00 48.73 ? 28 TRP A N 1 ATOM 200 C CA . TRP A 1 28 ? 20.291 -26.417 -13.369 1.00 49.10 ? 28 TRP A CA 1 ATOM 201 C C . TRP A 1 28 ? 21.403 -26.582 -12.330 1.00 48.66 ? 28 TRP A C 1 ATOM 202 O O . TRP A 1 28 ? 21.156 -26.485 -11.128 1.00 50.77 ? 28 TRP A O 1 ATOM 203 C CB . TRP A 1 28 ? 20.170 -24.947 -13.823 1.00 48.81 ? 28 TRP A CB 1 ATOM 204 C CG . TRP A 1 28 ? 20.106 -23.895 -12.714 1.00 48.12 ? 28 TRP A CG 1 ATOM 205 C CD1 . TRP A 1 28 ? 21.167 -23.236 -12.141 1.00 47.71 ? 28 TRP A CD1 1 ATOM 206 C CD2 . TRP A 1 28 ? 18.931 -23.370 -12.086 1.00 47.22 ? 28 TRP A CD2 1 ATOM 207 N NE1 . TRP A 1 28 ? 20.724 -22.349 -11.190 1.00 47.62 ? 28 TRP A NE1 1 ATOM 208 C CE2 . TRP A 1 28 ? 19.357 -22.410 -11.132 1.00 47.15 ? 28 TRP A CE2 1 ATOM 209 C CE3 . TRP A 1 28 ? 17.562 -23.620 -12.229 1.00 47.62 ? 28 TRP A CE3 1 ATOM 210 C CZ2 . TRP A 1 28 ? 18.458 -21.697 -10.328 1.00 46.39 ? 28 TRP A CZ2 1 ATOM 211 C CZ3 . TRP A 1 28 ? 16.660 -22.906 -11.418 1.00 48.47 ? 28 TRP A CZ3 1 ATOM 212 C CH2 . TRP A 1 28 ? 17.118 -21.959 -10.482 1.00 47.31 ? 28 TRP A CH2 1 ATOM 213 N N . CYS A 1 29 ? 22.619 -26.839 -12.799 1.00 47.57 ? 29 CYS A N 1 ATOM 214 C CA . CYS A 1 29 ? 23.772 -26.913 -11.914 1.00 47.71 ? 29 CYS A CA 1 ATOM 215 C C . CYS A 1 29 ? 24.142 -25.514 -11.495 1.00 47.19 ? 29 CYS A C 1 ATOM 216 O O . CYS A 1 29 ? 24.189 -24.618 -12.324 1.00 48.36 ? 29 CYS A O 1 ATOM 217 C CB . CYS A 1 29 ? 24.985 -27.552 -12.597 1.00 49.17 ? 29 CYS A CB 1 ATOM 218 S SG . CYS A 1 29 ? 24.951 -29.357 -12.654 1.00 56.70 ? 29 CYS A SG 1 ATOM 219 N N . ASP A 1 30 ? 24.380 -25.334 -10.201 1.00 47.47 ? 30 ASP A N 1 ATOM 220 C CA . ASP A 1 30 ? 25.051 -24.147 -9.683 1.00 45.28 ? 30 ASP A CA 1 ATOM 221 C C . ASP A 1 30 ? 26.397 -24.630 -9.152 1.00 43.41 ? 30 ASP A C 1 ATOM 222 O O . ASP A 1 30 ? 26.797 -25.757 -9.422 1.00 41.49 ? 30 ASP A O 1 ATOM 223 C CB . ASP A 1 30 ? 24.177 -23.422 -8.630 1.00 44.92 ? 30 ASP A CB 1 ATOM 224 C CG . ASP A 1 30 ? 24.072 -24.163 -7.302 1.00 44.27 ? 30 ASP A CG 1 ATOM 225 O OD1 . ASP A 1 30 ? 24.691 -25.230 -7.126 1.00 46.49 ? 30 ASP A OD1 1 ATOM 226 O OD2 . ASP A 1 30 ? 23.357 -23.668 -6.413 1.00 43.72 ? 30 ASP A OD2 1 ATOM 227 N N . VAL A 1 31 ? 27.080 -23.788 -8.391 1.00 44.14 ? 31 VAL A N 1 ATOM 228 C CA . VAL A 1 31 ? 28.391 -24.116 -7.845 1.00 45.48 ? 31 VAL A CA 1 ATOM 229 C C . VAL A 1 31 ? 28.448 -25.386 -6.975 1.00 44.29 ? 31 VAL A C 1 ATOM 230 O O . VAL A 1 31 ? 29.489 -26.024 -6.908 1.00 43.26 ? 31 VAL A O 1 ATOM 231 C CB . VAL A 1 31 ? 28.933 -22.928 -7.030 1.00 49.77 ? 31 VAL A CB 1 ATOM 232 C CG1 . VAL A 1 31 ? 28.184 -22.787 -5.704 1.00 52.35 ? 31 VAL A CG1 1 ATOM 233 C CG2 . VAL A 1 31 ? 30.431 -23.066 -6.802 1.00 52.84 ? 31 VAL A CG2 1 ATOM 234 N N . PHE A 1 32 ? 27.342 -25.740 -6.321 1.00 44.45 ? 32 PHE A N 1 ATOM 235 C CA . PHE A 1 32 ? 27.267 -26.938 -5.468 1.00 45.74 ? 32 PHE A CA 1 ATOM 236 C C . PHE A 1 32 ? 26.875 -28.229 -6.197 1.00 46.55 ? 32 PHE A C 1 ATOM 237 O O . PHE A 1 32 ? 26.631 -29.245 -5.537 1.00 46.37 ? 32 PHE A O 1 ATOM 238 C CB . PHE A 1 32 ? 26.268 -26.704 -4.315 1.00 46.13 ? 32 PHE A CB 1 ATOM 239 C CG . PHE A 1 32 ? 26.648 -25.572 -3.404 1.00 45.47 ? 32 PHE A CG 1 ATOM 240 C CD1 . PHE A 1 32 ? 27.617 -25.751 -2.431 1.00 45.13 ? 32 PHE A CD1 1 ATOM 241 C CD2 . PHE A 1 32 ? 26.043 -24.329 -3.523 1.00 45.83 ? 32 PHE A CD2 1 ATOM 242 C CE1 . PHE A 1 32 ? 27.977 -24.716 -1.589 1.00 45.63 ? 32 PHE A CE1 1 ATOM 243 C CE2 . PHE A 1 32 ? 26.399 -23.286 -2.685 1.00 46.19 ? 32 PHE A CE2 1 ATOM 244 C CZ . PHE A 1 32 ? 27.369 -23.480 -1.717 1.00 46.41 ? 32 PHE A CZ 1 ATOM 245 N N . CYS A 1 33 ? 26.835 -28.213 -7.532 1.00 48.96 ? 33 CYS A N 1 ATOM 246 C CA . CYS A 1 33 ? 26.194 -29.297 -8.291 1.00 50.09 ? 33 CYS A CA 1 ATOM 247 C C . CYS A 1 33 ? 26.787 -30.678 -8.009 1.00 50.20 ? 33 CYS A C 1 ATOM 248 O O . CYS A 1 33 ? 26.037 -31.647 -7.900 1.00 50.95 ? 33 CYS A O 1 ATOM 249 C CB . CYS A 1 33 ? 26.182 -29.018 -9.805 1.00 51.24 ? 33 CYS A CB 1 ATOM 250 S SG . CYS A 1 33 ? 24.960 -30.026 -10.695 1.00 54.99 ? 33 CYS A SG 1 ATOM 251 N N . SER A 1 34 ? 28.110 -30.763 -7.859 1.00 49.77 ? 34 SER A N 1 ATOM 252 C CA . SER A 1 34 ? 28.771 -32.055 -7.612 1.00 49.49 ? 34 SER A CA 1 ATOM 253 C C . SER A 1 34 ? 28.487 -32.652 -6.232 1.00 49.62 ? 34 SER A C 1 ATOM 254 O O . SER A 1 34 ? 28.601 -33.862 -6.071 1.00 54.21 ? 34 SER A O 1 ATOM 255 C CB . SER A 1 34 ? 30.289 -31.972 -7.841 1.00 48.59 ? 34 SER A CB 1 ATOM 256 O OG . SER A 1 34 ? 30.924 -31.183 -6.862 1.00 48.80 ? 34 SER A OG 1 ATOM 257 N N . SER A 1 35 ? 28.126 -31.822 -5.250 1.00 49.26 ? 35 SER A N 1 ATOM 258 C CA . SER A 1 35 ? 27.845 -32.297 -3.884 1.00 47.80 ? 35 SER A CA 1 ATOM 259 C C . SER A 1 35 ? 26.359 -32.471 -3.603 1.00 45.91 ? 35 SER A C 1 ATOM 260 O O . SER A 1 35 ? 25.979 -33.462 -2.992 1.00 49.19 ? 35 SER A O 1 ATOM 261 C CB . SER A 1 35 ? 28.485 -31.379 -2.829 1.00 48.28 ? 35 SER A CB 1 ATOM 262 O OG . SER A 1 35 ? 28.302 -30.007 -3.136 1.00 51.00 ? 35 SER A OG 1 ATOM 263 N N . ARG A 1 36 ? 25.530 -31.524 -4.043 1.00 45.03 ? 36 ARG A N 1 ATOM 264 C CA . ARG A 1 36 ? 24.082 -31.526 -3.751 1.00 43.87 ? 36 ARG A CA 1 ATOM 265 C C . ARG A 1 36 ? 23.183 -31.826 -4.962 1.00 41.84 ? 36 ARG A C 1 ATOM 266 O O . ARG A 1 36 ? 21.966 -31.889 -4.813 1.00 39.42 ? 36 ARG A O 1 ATOM 267 C CB . ARG A 1 36 ? 23.659 -30.169 -3.188 1.00 45.81 ? 36 ARG A CB 1 ATOM 268 C CG . ARG A 1 36 ? 24.541 -29.606 -2.087 1.00 48.50 ? 36 ARG A CG 1 ATOM 269 C CD . ARG A 1 36 ? 24.068 -28.211 -1.709 1.00 50.79 ? 36 ARG A CD 1 ATOM 270 N NE . ARG A 1 36 ? 24.977 -27.523 -0.791 1.00 51.91 ? 36 ARG A NE 1 ATOM 271 C CZ . ARG A 1 36 ? 24.860 -26.248 -0.415 1.00 51.72 ? 36 ARG A CZ 1 ATOM 272 N NH1 . ARG A 1 36 ? 23.870 -25.479 -0.868 1.00 50.27 ? 36 ARG A NH1 1 ATOM 273 N NH2 . ARG A 1 36 ? 25.744 -25.734 0.429 1.00 52.70 ? 36 ARG A NH2 1 ATOM 274 N N . GLY A 1 37 ? 23.761 -31.985 -6.152 1.00 40.55 ? 37 GLY A N 1 ATOM 275 C CA . GLY A 1 37 ? 22.970 -32.162 -7.366 1.00 41.88 ? 37 GLY A CA 1 ATOM 276 C C . GLY A 1 37 ? 22.431 -30.844 -7.887 1.00 43.31 ? 37 GLY A C 1 ATOM 277 O O . GLY A 1 37 ? 22.798 -29.776 -7.393 1.00 44.81 ? 37 GLY A O 1 ATOM 278 N N . LYS A 1 38 ? 21.556 -30.922 -8.886 1.00 43.80 ? 38 LYS A N 1 ATOM 279 C CA . LYS A 1 38 ? 21.023 -29.727 -9.547 1.00 44.50 ? 38 LYS A CA 1 ATOM 280 C C . LYS A 1 38 ? 20.062 -28.942 -8.663 1.00 43.48 ? 38 LYS A C 1 ATOM 281 O O . LYS A 1 38 ? 19.382 -29.520 -7.817 1.00 43.45 ? 38 LYS A O 1 ATOM 282 C CB . LYS A 1 38 ? 20.327 -30.098 -10.864 1.00 47.26 ? 38 LYS A CB 1 ATOM 283 C CG . LYS A 1 38 ? 21.308 -30.399 -11.986 1.00 50.12 ? 38 LYS A CG 1 ATOM 284 C CD . LYS A 1 38 ? 20.614 -30.857 -13.257 1.00 52.59 ? 38 LYS A CD 1 ATOM 285 C CE . LYS A 1 38 ? 21.615 -31.064 -14.381 1.00 54.15 ? 38 LYS A CE 1 ATOM 286 N NZ . LYS A 1 38 ? 21.066 -31.950 -15.445 1.00 56.22 ? 38 LYS A NZ 1 ATOM 287 N N . VAL A 1 39 ? 20.017 -27.625 -8.877 1.00 42.02 ? 39 VAL A N 1 ATOM 288 C CA . VAL A 1 39 ? 19.008 -26.757 -8.257 1.00 41.24 ? 39 VAL A CA 1 ATOM 289 C C . VAL A 1 39 ? 17.649 -27.174 -8.820 1.00 40.61 ? 39 VAL A C 1 ATOM 290 O O . VAL A 1 39 ? 17.554 -27.573 -9.985 1.00 38.77 ? 39 VAL A O 1 ATOM 291 C CB . VAL A 1 39 ? 19.259 -25.246 -8.545 1.00 41.83 ? 39 VAL A CB 1 ATOM 292 C CG1 . VAL A 1 39 ? 18.133 -24.381 -7.979 1.00 41.39 ? 39 VAL A CG1 1 ATOM 293 C CG2 . VAL A 1 39 ? 20.603 -24.788 -7.985 1.00 41.85 ? 39 VAL A CG2 1 ATOM 294 N N . VAL A 1 40 ? 16.616 -27.102 -7.987 1.00 40.97 ? 40 VAL A N 1 ATOM 295 C CA . VAL A 1 40 ? 15.268 -27.517 -8.366 1.00 42.52 ? 40 VAL A CA 1 ATOM 296 C C . VAL A 1 40 ? 14.326 -26.355 -8.108 1.00 45.15 ? 40 VAL A C 1 ATOM 297 O O . VAL A 1 40 ? 14.221 -25.882 -6.971 1.00 46.42 ? 40 VAL A O 1 ATOM 298 C CB . VAL A 1 40 ? 14.802 -28.739 -7.551 1.00 41.89 ? 40 VAL A CB 1 ATOM 299 C CG1 . VAL A 1 40 ? 13.406 -29.176 -7.981 1.00 41.06 ? 40 VAL A CG1 1 ATOM 300 C CG2 . VAL A 1 40 ? 15.804 -29.884 -7.688 1.00 43.03 ? 40 VAL A CG2 1 ATOM 301 N N . GLU A 1 41 ? 13.657 -25.895 -9.163 1.00 46.11 ? 41 GLU A N 1 ATOM 302 C CA . GLU A 1 41 ? 12.662 -24.834 -9.068 1.00 47.90 ? 41 GLU A CA 1 ATOM 303 C C . GLU A 1 41 ? 11.325 -25.375 -9.576 1.00 46.71 ? 41 GLU A C 1 ATOM 304 O O . GLU A 1 41 ? 11.274 -25.992 -10.639 1.00 45.13 ? 41 GLU A O 1 ATOM 305 C CB . GLU A 1 41 ? 13.120 -23.629 -9.886 1.00 50.72 ? 41 GLU A CB 1 ATOM 306 C CG . GLU A 1 41 ? 12.210 -22.413 -9.818 1.00 53.95 ? 41 GLU A CG 1 ATOM 307 C CD . GLU A 1 41 ? 12.824 -21.206 -10.508 1.00 58.28 ? 41 GLU A CD 1 ATOM 308 O OE1 . GLU A 1 41 ? 12.281 -20.776 -11.556 1.00 60.27 ? 41 GLU A OE1 1 ATOM 309 O OE2 . GLU A 1 41 ? 13.863 -20.706 -10.009 1.00 59.51 ? 41 GLU A OE2 1 ATOM 310 N N . LEU A 1 42 ? 10.260 -25.145 -8.802 1.00 45.62 ? 42 LEU A N 1 ATOM 311 C CA . LEU A 1 42 ? 8.907 -25.626 -9.111 1.00 44.39 ? 42 LEU A CA 1 ATOM 312 C C . LEU A 1 42 ? 7.900 -24.476 -9.007 1.00 46.42 ? 42 LEU A C 1 ATOM 313 O O . LEU A 1 42 ? 8.018 -23.626 -8.111 1.00 44.93 ? 42 LEU A O 1 ATOM 314 C CB . LEU A 1 42 ? 8.514 -26.737 -8.137 1.00 42.16 ? 42 LEU A CB 1 ATOM 315 C CG . LEU A 1 42 ? 9.513 -27.885 -7.994 1.00 40.90 ? 42 LEU A CG 1 ATOM 316 C CD1 . LEU A 1 42 ? 9.105 -28.838 -6.885 1.00 40.48 ? 42 LEU A CD1 1 ATOM 317 C CD2 . LEU A 1 42 ? 9.652 -28.624 -9.309 1.00 40.63 ? 42 LEU A CD2 1 ATOM 318 N N . GLY A 1 43 ? 6.918 -24.438 -9.912 1.00 47.31 ? 43 GLY A N 1 ATOM 319 C CA . GLY A 1 43 ? 5.919 -23.371 -9.869 1.00 49.10 ? 43 GLY A CA 1 ATOM 320 C C . GLY A 1 43 ? 4.837 -23.369 -10.930 1.00 49.87 ? 43 GLY A C 1 ATOM 321 O O . GLY A 1 43 ? 4.550 -24.387 -11.544 1.00 46.48 ? 43 GLY A O 1 ATOM 322 N N . CYS A 1 44 ? 4.242 -22.193 -11.116 1.00 55.77 ? 44 CYS A N 1 ATOM 323 C CA . CYS A 1 44 ? 3.166 -21.959 -12.070 1.00 62.36 ? 44 CYS A CA 1 ATOM 324 C C . CYS A 1 44 ? 3.662 -21.136 -13.251 1.00 65.79 ? 44 CYS A C 1 ATOM 325 O O . CYS A 1 44 ? 4.539 -20.280 -13.101 1.00 67.34 ? 44 CYS A O 1 ATOM 326 C CB . CYS A 1 44 ? 2.049 -21.156 -11.399 1.00 67.16 ? 44 CYS A CB 1 ATOM 327 S SG . CYS A 1 44 ? 1.335 -21.892 -9.912 1.00 71.65 ? 44 CYS A SG 1 ATOM 328 N N . ALA A 1 45 ? 3.076 -21.375 -14.418 1.00 68.43 ? 45 ALA A N 1 ATOM 329 C CA . ALA A 1 45 ? 3.290 -20.512 -15.576 1.00 70.55 ? 45 ALA A CA 1 ATOM 330 C C . ALA A 1 45 ? 2.112 -20.627 -16.535 1.00 73.22 ? 45 ALA A C 1 ATOM 331 O O . ALA A 1 45 ? 1.467 -21.677 -16.604 1.00 72.23 ? 45 ALA A O 1 ATOM 332 C CB . ALA A 1 45 ? 4.590 -20.881 -16.274 1.00 71.68 ? 45 ALA A CB 1 ATOM 333 N N . ALA A 1 46 ? 1.831 -19.544 -17.260 1.00 78.40 ? 46 ALA A N 1 ATOM 334 C CA . ALA A 1 46 ? 0.793 -19.547 -18.302 1.00 80.08 ? 46 ALA A CA 1 ATOM 335 C C . ALA A 1 46 ? 1.271 -20.353 -19.503 1.00 82.14 ? 46 ALA A C 1 ATOM 336 O O . ALA A 1 46 ? 0.653 -21.357 -19.866 1.00 81.53 ? 46 ALA A O 1 ATOM 337 C CB . ALA A 1 46 ? 0.424 -18.125 -18.709 1.00 79.58 ? 46 ALA A CB 1 ATOM 338 N N . THR A 1 47 ? 2.381 -19.912 -20.094 1.00 84.16 ? 47 THR A N 1 ATOM 339 C CA . THR A 1 47 ? 3.084 -20.658 -21.141 1.00 84.51 ? 47 THR A CA 1 ATOM 340 C C . THR A 1 47 ? 4.366 -21.245 -20.557 1.00 85.31 ? 47 THR A C 1 ATOM 341 O O . THR A 1 47 ? 4.832 -20.811 -19.497 1.00 82.36 ? 47 THR A O 1 ATOM 342 C CB . THR A 1 47 ? 3.423 -19.759 -22.345 1.00 82.92 ? 47 THR A CB 1 ATOM 343 O OG1 . THR A 1 47 ? 4.045 -18.549 -21.889 1.00 78.48 ? 47 THR A OG1 1 ATOM 344 C CG2 . THR A 1 47 ? 2.160 -19.417 -23.125 1.00 82.67 ? 47 THR A CG2 1 ATOM 345 N N . CYS A 1 48 ? 4.931 -22.224 -21.261 1.00 87.81 ? 48 CYS A N 1 ATOM 346 C CA . CYS A 1 48 ? 6.097 -22.966 -20.771 1.00 88.53 ? 48 CYS A CA 1 ATOM 347 C C . CYS A 1 48 ? 7.336 -22.053 -20.776 1.00 90.26 ? 48 CYS A C 1 ATOM 348 O O . CYS A 1 48 ? 7.602 -21.398 -21.791 1.00 86.91 ? 48 CYS A O 1 ATOM 349 C CB . CYS A 1 48 ? 6.330 -24.218 -21.629 1.00 88.68 ? 48 CYS A CB 1 ATOM 350 S SG . CYS A 1 48 ? 7.269 -25.547 -20.836 1.00 92.79 ? 48 CYS A SG 1 ATOM 351 N N . PRO A 1 49 ? 8.090 -21.995 -19.648 1.00 91.28 ? 49 PRO A N 1 ATOM 352 C CA . PRO A 1 49 ? 9.160 -20.986 -19.562 1.00 90.24 ? 49 PRO A CA 1 ATOM 353 C C . PRO A 1 49 ? 10.336 -21.215 -20.513 1.00 90.64 ? 49 PRO A C 1 ATOM 354 O O . PRO A 1 49 ? 10.484 -22.301 -21.081 1.00 89.09 ? 49 PRO A O 1 ATOM 355 C CB . PRO A 1 49 ? 9.624 -21.048 -18.094 1.00 89.16 ? 49 PRO A CB 1 ATOM 356 C CG . PRO A 1 49 ? 8.944 -22.207 -17.466 1.00 88.83 ? 49 PRO A CG 1 ATOM 357 C CD . PRO A 1 49 ? 8.069 -22.889 -18.473 1.00 90.23 ? 49 PRO A CD 1 ATOM 358 N N . SER A 1 50 ? 11.152 -20.174 -20.671 1.00 95.54 ? 50 SER A N 1 ATOM 359 C CA . SER A 1 50 ? 12.293 -20.188 -21.586 1.00 97.36 ? 50 SER A CA 1 ATOM 360 C C . SER A 1 50 ? 13.426 -21.060 -21.045 1.00 97.75 ? 50 SER A C 1 ATOM 361 O O . SER A 1 50 ? 13.985 -20.777 -19.979 1.00 98.47 ? 50 SER A O 1 ATOM 362 C CB . SER A 1 50 ? 12.822 -18.765 -21.819 1.00 97.90 ? 50 SER A CB 1 ATOM 363 O OG . SER A 1 50 ? 11.796 -17.889 -22.251 1.00 99.27 ? 50 SER A OG 1 ATOM 364 N N . LYS A 1 51 ? 13.752 -22.120 -21.781 1.00 96.90 ? 51 LYS A N 1 ATOM 365 C CA . LYS A 1 51 ? 14.928 -22.932 -21.491 1.00 95.49 ? 51 LYS A CA 1 ATOM 366 C C . LYS A 1 51 ? 16.186 -22.159 -21.901 1.00 95.82 ? 51 LYS A C 1 ATOM 367 O O . LYS A 1 51 ? 16.155 -21.338 -22.817 1.00 95.43 ? 51 LYS A O 1 ATOM 368 C CB . LYS A 1 51 ? 14.858 -24.269 -22.238 1.00 94.59 ? 51 LYS A CB 1 ATOM 369 C CG . LYS A 1 51 ? 15.870 -25.307 -21.770 1.00 92.48 ? 51 LYS A CG 1 ATOM 370 C CD . LYS A 1 51 ? 15.891 -26.525 -22.682 1.00 90.91 ? 51 LYS A CD 1 ATOM 371 C CE . LYS A 1 51 ? 17.186 -27.314 -22.544 1.00 89.17 ? 51 LYS A CE 1 ATOM 372 N NZ . LYS A 1 51 ? 18.388 -26.576 -23.028 1.00 85.80 ? 51 LYS A NZ 1 ATOM 373 N N . LYS A 1 52 ? 17.279 -22.420 -21.193 1.00 97.24 ? 52 LYS A N 1 ATOM 374 C CA . LYS A 1 52 ? 18.607 -21.900 -21.524 1.00 99.13 ? 52 LYS A CA 1 ATOM 375 C C . LYS A 1 52 ? 19.534 -23.115 -21.626 1.00 101.70 ? 52 LYS A C 1 ATOM 376 O O . LYS A 1 52 ? 19.219 -24.163 -21.055 1.00 107.93 ? 52 LYS A O 1 ATOM 377 C CB . LYS A 1 52 ? 19.062 -20.909 -20.449 1.00 97.27 ? 52 LYS A CB 1 ATOM 378 C CG . LYS A 1 52 ? 18.169 -19.675 -20.376 1.00 97.38 ? 52 LYS A CG 1 ATOM 379 C CD . LYS A 1 52 ? 18.250 -18.948 -19.042 1.00 95.90 ? 52 LYS A CD 1 ATOM 380 C CE . LYS A 1 52 ? 17.083 -17.982 -18.877 1.00 93.57 ? 52 LYS A CE 1 ATOM 381 N NZ . LYS A 1 52 ? 16.971 -17.479 -17.484 1.00 93.72 ? 52 LYS A NZ 1 ATOM 382 N N . PRO A 1 53 ? 20.668 -22.998 -22.351 1.00 101.72 ? 53 PRO A N 1 ATOM 383 C CA . PRO A 1 53 ? 21.479 -24.197 -22.659 1.00 102.18 ? 53 PRO A CA 1 ATOM 384 C C . PRO A 1 53 ? 21.830 -25.062 -21.438 1.00 104.45 ? 53 PRO A C 1 ATOM 385 O O . PRO A 1 53 ? 21.809 -26.293 -21.524 1.00 105.03 ? 53 PRO A O 1 ATOM 386 C CB . PRO A 1 53 ? 22.753 -23.616 -23.290 1.00 102.18 ? 53 PRO A CB 1 ATOM 387 C CG . PRO A 1 53 ? 22.377 -22.250 -23.749 1.00 102.74 ? 53 PRO A CG 1 ATOM 388 C CD . PRO A 1 53 ? 21.338 -21.759 -22.788 1.00 102.11 ? 53 PRO A CD 1 ATOM 389 N N . TYR A 1 54 ? 22.123 -24.401 -20.319 1.00 105.44 ? 54 TYR A N 1 ATOM 390 C CA . TYR A 1 54 ? 22.490 -25.063 -19.059 1.00 105.20 ? 54 TYR A CA 1 ATOM 391 C C . TYR A 1 54 ? 21.285 -25.546 -18.224 1.00 99.95 ? 54 TYR A C 1 ATOM 392 O O . TYR A 1 54 ? 21.408 -26.528 -17.487 1.00 98.49 ? 54 TYR A O 1 ATOM 393 C CB . TYR A 1 54 ? 23.437 -24.166 -18.226 1.00 111.77 ? 54 TYR A CB 1 ATOM 394 C CG . TYR A 1 54 ? 22.845 -22.895 -17.611 1.00 115.84 ? 54 TYR A CG 1 ATOM 395 C CD1 . TYR A 1 54 ? 22.728 -21.706 -18.353 1.00 115.97 ? 54 TYR A CD1 1 ATOM 396 C CD2 . TYR A 1 54 ? 22.451 -22.867 -16.269 1.00 116.78 ? 54 TYR A CD2 1 ATOM 397 C CE1 . TYR A 1 54 ? 22.205 -20.549 -17.785 1.00 117.39 ? 54 TYR A CE1 1 ATOM 398 C CE2 . TYR A 1 54 ? 21.929 -21.712 -15.693 1.00 118.84 ? 54 TYR A CE2 1 ATOM 399 C CZ . TYR A 1 54 ? 21.808 -20.558 -16.452 1.00 120.61 ? 54 TYR A CZ 1 ATOM 400 O OH . TYR A 1 54 ? 21.290 -19.416 -15.883 1.00 122.06 ? 54 TYR A OH 1 ATOM 401 N N . GLU A 1 55 ? 20.138 -24.867 -18.347 1.00 92.79 ? 55 GLU A N 1 ATOM 402 C CA . GLU A 1 55 ? 18.906 -25.235 -17.625 1.00 86.27 ? 55 GLU A CA 1 ATOM 403 C C . GLU A 1 55 ? 18.184 -26.421 -18.279 1.00 82.83 ? 55 GLU A C 1 ATOM 404 O O . GLU A 1 55 ? 18.579 -26.880 -19.351 1.00 82.66 ? 55 GLU A O 1 ATOM 405 C CB . GLU A 1 55 ? 17.948 -24.039 -17.539 1.00 86.14 ? 55 GLU A CB 1 ATOM 406 C CG . GLU A 1 55 ? 18.507 -22.805 -16.843 1.00 86.85 ? 55 GLU A CG 1 ATOM 407 C CD . GLU A 1 55 ? 17.465 -21.712 -16.636 1.00 88.18 ? 55 GLU A CD 1 ATOM 408 O OE1 . GLU A 1 55 ? 16.410 -21.741 -17.311 1.00 85.75 ? 55 GLU A OE1 1 ATOM 409 O OE2 . GLU A 1 55 ? 17.707 -20.809 -15.802 1.00 88.16 ? 55 GLU A OE2 1 ATOM 410 N N . GLU A 1 56 ? 17.125 -26.903 -17.624 1.00 80.80 ? 56 GLU A N 1 ATOM 411 C CA . GLU A 1 56 ? 16.365 -28.070 -18.080 1.00 78.94 ? 56 GLU A CA 1 ATOM 412 C C . GLU A 1 56 ? 14.894 -27.984 -17.641 1.00 74.56 ? 56 GLU A C 1 ATOM 413 O O . GLU A 1 56 ? 14.474 -28.622 -16.674 1.00 73.80 ? 56 GLU A O 1 ATOM 414 C CB . GLU A 1 56 ? 17.025 -29.343 -17.539 1.00 81.81 ? 56 GLU A CB 1 ATOM 415 C CG . GLU A 1 56 ? 16.428 -30.652 -18.040 1.00 85.57 ? 56 GLU A CG 1 ATOM 416 C CD . GLU A 1 56 ? 16.475 -31.752 -16.995 1.00 88.82 ? 56 GLU A CD 1 ATOM 417 O OE1 . GLU A 1 56 ? 17.544 -31.937 -16.367 1.00 88.59 ? 56 GLU A OE1 1 ATOM 418 O OE2 . GLU A 1 56 ? 15.438 -32.427 -16.802 1.00 91.93 ? 56 GLU A OE2 1 ATOM 419 N N . VAL A 1 57 ? 14.124 -27.189 -18.377 1.00 72.95 ? 57 VAL A N 1 ATOM 420 C CA . VAL A 1 57 ? 12.697 -26.988 -18.110 1.00 73.71 ? 57 VAL A CA 1 ATOM 421 C C . VAL A 1 57 ? 11.844 -28.183 -18.556 1.00 74.00 ? 57 VAL A C 1 ATOM 422 O O . VAL A 1 57 ? 12.176 -28.855 -19.527 1.00 77.37 ? 57 VAL A O 1 ATOM 423 C CB . VAL A 1 57 ? 12.182 -25.683 -18.783 1.00 73.53 ? 57 VAL A CB 1 ATOM 424 C CG1 . VAL A 1 57 ? 12.054 -25.826 -20.301 1.00 75.62 ? 57 VAL A CG1 1 ATOM 425 C CG2 . VAL A 1 57 ? 10.855 -25.242 -18.182 1.00 72.86 ? 57 VAL A CG2 1 ATOM 426 N N . THR A 1 58 ? 10.765 -28.450 -17.822 1.00 76.64 ? 58 THR A N 1 ATOM 427 C CA . THR A 1 58 ? 9.680 -29.338 -18.277 1.00 78.99 ? 58 THR A CA 1 ATOM 428 C C . THR A 1 58 ? 8.323 -28.731 -17.892 1.00 80.20 ? 58 THR A C 1 ATOM 429 O O . THR A 1 58 ? 8.255 -27.875 -17.006 1.00 80.86 ? 58 THR A O 1 ATOM 430 C CB . THR A 1 58 ? 9.789 -30.770 -17.701 1.00 79.65 ? 58 THR A CB 1 ATOM 431 O OG1 . THR A 1 58 ? 9.591 -30.747 -16.283 1.00 82.31 ? 58 THR A OG1 1 ATOM 432 C CG2 . THR A 1 58 ? 11.148 -31.393 -18.015 1.00 81.57 ? 58 THR A CG2 1 ATOM 433 N N . CYS A 1 59 ? 7.258 -29.173 -18.564 1.00 79.23 ? 59 CYS A N 1 ATOM 434 C CA . CYS A 1 59 ? 5.900 -28.655 -18.347 1.00 77.42 ? 59 CYS A CA 1 ATOM 435 C C . CYS A 1 59 ? 4.870 -29.776 -18.307 1.00 73.66 ? 59 CYS A C 1 ATOM 436 O O . CYS A 1 59 ? 5.103 -30.852 -18.849 1.00 73.13 ? 59 CYS A O 1 ATOM 437 C CB . CYS A 1 59 ? 5.540 -27.664 -19.454 1.00 81.03 ? 59 CYS A CB 1 ATOM 438 S SG . CYS A 1 59 ? 6.188 -26.004 -19.163 1.00 91.26 ? 59 CYS A SG 1 ATOM 439 N N . CYS A 1 60 ? 3.735 -29.516 -17.656 1.00 71.83 ? 60 CYS A N 1 ATOM 440 C CA . CYS A 1 60 ? 2.588 -30.446 -17.677 1.00 71.90 ? 60 CYS A CA 1 ATOM 441 C C . CYS A 1 60 ? 1.281 -29.792 -17.192 1.00 69.57 ? 60 CYS A C 1 ATOM 442 O O . CYS A 1 60 ? 1.312 -28.780 -16.485 1.00 67.45 ? 60 CYS A O 1 ATOM 443 C CB . CYS A 1 60 ? 2.894 -31.718 -16.881 1.00 69.22 ? 60 CYS A CB 1 ATOM 444 S SG . CYS A 1 60 ? 3.669 -31.397 -15.292 1.00 69.02 ? 60 CYS A SG 1 ATOM 445 N N . SER A 1 61 ? 0.152 -30.391 -17.585 1.00 67.31 ? 61 SER A N 1 ATOM 446 C CA . SER A 1 61 ? -1.185 -29.789 -17.425 1.00 67.21 ? 61 SER A CA 1 ATOM 447 C C . SER A 1 61 ? -2.126 -30.562 -16.497 1.00 65.50 ? 61 SER A C 1 ATOM 448 O O . SER A 1 61 ? -3.339 -30.389 -16.572 1.00 67.05 ? 61 SER A O 1 ATOM 449 C CB . SER A 1 61 ? -1.854 -29.663 -18.793 1.00 67.66 ? 61 SER A CB 1 ATOM 450 O OG . SER A 1 61 ? -0.952 -29.141 -19.741 1.00 72.57 ? 61 SER A OG 1 ATOM 451 N N . THR A 1 62 ? -1.565 -31.370 -15.604 1.00 65.07 ? 62 THR A N 1 ATOM 452 C CA . THR A 1 62 ? -2.345 -32.217 -14.690 1.00 66.43 ? 62 THR A CA 1 ATOM 453 C C . THR A 1 62 ? -1.902 -31.959 -13.234 1.00 64.93 ? 62 THR A C 1 ATOM 454 O O . THR A 1 62 ? -0.810 -31.450 -12.988 1.00 64.37 ? 62 THR A O 1 ATOM 455 C CB . THR A 1 62 ? -2.273 -33.723 -15.078 1.00 66.96 ? 62 THR A CB 1 ATOM 456 O OG1 . THR A 1 62 ? -2.428 -34.540 -13.910 1.00 68.28 ? 62 THR A OG1 1 ATOM 457 C CG2 . THR A 1 62 ? -0.951 -34.091 -15.762 1.00 67.75 ? 62 THR A CG2 1 ATOM 458 N N . ASP A 1 63 ? -2.765 -32.301 -12.280 1.00 61.90 ? 63 ASP A N 1 ATOM 459 C CA . ASP A 1 63 ? -2.564 -31.920 -10.875 1.00 60.27 ? 63 ASP A CA 1 ATOM 460 C C . ASP A 1 63 ? -1.346 -32.595 -10.233 1.00 58.80 ? 63 ASP A C 1 ATOM 461 O O . ASP A 1 63 ? -1.179 -33.806 -10.345 1.00 59.97 ? 63 ASP A O 1 ATOM 462 C CB . ASP A 1 63 ? -3.828 -32.208 -10.040 1.00 60.21 ? 63 ASP A CB 1 ATOM 463 C CG . ASP A 1 63 ? -4.895 -31.111 -10.162 1.00 60.12 ? 63 ASP A CG 1 ATOM 464 O OD1 . ASP A 1 63 ? -4.720 -30.143 -10.936 1.00 58.57 ? 63 ASP A OD1 1 ATOM 465 O OD2 . ASP A 1 63 ? -5.921 -31.215 -9.459 1.00 60.72 ? 63 ASP A OD2 1 ATOM 466 N N . LYS A 1 64 ? -0.510 -31.787 -9.573 1.00 57.00 ? 64 LYS A N 1 ATOM 467 C CA . LYS A 1 64 ? 0.711 -32.234 -8.888 1.00 57.05 ? 64 LYS A CA 1 ATOM 468 C C . LYS A 1 64 ? 1.700 -32.988 -9.795 1.00 56.49 ? 64 LYS A C 1 ATOM 469 O O . LYS A 1 64 ? 2.457 -33.852 -9.341 1.00 54.50 ? 64 LYS A O 1 ATOM 470 C CB . LYS A 1 64 ? 0.352 -33.074 -7.658 1.00 59.27 ? 64 LYS A CB 1 ATOM 471 C CG . LYS A 1 64 ? -0.481 -32.350 -6.611 1.00 60.85 ? 64 LYS A CG 1 ATOM 472 C CD . LYS A 1 64 ? -0.633 -33.236 -5.385 1.00 62.71 ? 64 LYS A CD 1 ATOM 473 C CE . LYS A 1 64 ? -1.509 -32.619 -4.316 1.00 63.78 ? 64 LYS A CE 1 ATOM 474 N NZ . LYS A 1 64 ? -1.750 -33.606 -3.228 1.00 64.85 ? 64 LYS A NZ 1 ATOM 475 N N . CYS A 1 65 ? 1.722 -32.619 -11.072 1.00 56.43 ? 65 CYS A N 1 ATOM 476 C CA . CYS A 1 65 ? 2.561 -33.288 -12.060 1.00 56.11 ? 65 CYS A CA 1 ATOM 477 C C . CYS A 1 65 ? 4.023 -32.822 -12.067 1.00 54.68 ? 65 CYS A C 1 ATOM 478 O O . CYS A 1 65 ? 4.805 -33.358 -12.855 1.00 55.47 ? 65 CYS A O 1 ATOM 479 C CB . CYS A 1 65 ? 1.974 -33.076 -13.454 1.00 58.25 ? 65 CYS A CB 1 ATOM 480 S SG . CYS A 1 65 ? 2.087 -31.366 -14.027 1.00 60.39 ? 65 CYS A SG 1 ATOM 481 N N . ASN A 1 66 ? 4.386 -31.841 -11.222 1.00 50.85 ? 66 ASN A N 1 ATOM 482 C CA . ASN A 1 66 ? 5.753 -31.287 -11.167 1.00 49.19 ? 66 ASN A CA 1 ATOM 483 C C . ASN A 1 66 ? 6.429 -31.476 -9.804 1.00 50.75 ? 66 ASN A C 1 ATOM 484 O O . ASN A 1 66 ? 6.909 -30.510 -9.207 1.00 52.19 ? 66 ASN A O 1 ATOM 485 C CB . ASN A 1 66 ? 5.753 -29.792 -11.557 1.00 48.05 ? 66 ASN A CB 1 ATOM 486 C CG . ASN A 1 66 ? 5.135 -28.890 -10.493 1.00 46.24 ? 66 ASN A CG 1 ATOM 487 O OD1 . ASN A 1 66 ? 4.191 -29.275 -9.800 1.00 45.63 ? 66 ASN A OD1 1 ATOM 488 N ND2 . ASN A 1 66 ? 5.674 -27.689 -10.358 1.00 43.47 ? 66 ASN A ND2 1 ATOM 489 N N . PRO A 1 67 ? 6.506 -32.724 -9.316 1.00 52.00 ? 67 PRO A N 1 ATOM 490 C CA . PRO A 1 67 ? 7.128 -32.917 -8.011 1.00 51.38 ? 67 PRO A CA 1 ATOM 491 C C . PRO A 1 67 ? 8.646 -32.740 -8.038 1.00 50.68 ? 67 PRO A C 1 ATOM 492 O O . PRO A 1 67 ? 9.255 -32.668 -9.109 1.00 50.18 ? 67 PRO A O 1 ATOM 493 C CB . PRO A 1 67 ? 6.785 -34.373 -7.692 1.00 51.33 ? 67 PRO A CB 1 ATOM 494 C CG . PRO A 1 67 ? 6.813 -35.025 -9.029 1.00 52.65 ? 67 PRO A CG 1 ATOM 495 C CD . PRO A 1 67 ? 6.188 -34.017 -9.955 1.00 52.21 ? 67 PRO A CD 1 ATOM 496 N N . HIS A 1 68 ? 9.229 -32.682 -6.845 1.00 51.15 ? 68 HIS A N 1 ATOM 497 C CA . HIS A 1 68 ? 10.668 -32.818 -6.652 1.00 50.84 ? 68 HIS A CA 1 ATOM 498 C C . HIS A 1 68 ? 11.098 -34.177 -7.240 1.00 53.42 ? 68 HIS A C 1 ATOM 499 O O . HIS A 1 68 ? 10.399 -35.169 -7.024 1.00 54.84 ? 68 HIS A O 1 ATOM 500 C CB . HIS A 1 68 ? 10.985 -32.759 -5.156 1.00 49.18 ? 68 HIS A CB 1 ATOM 501 C CG . HIS A 1 68 ? 12.430 -32.547 -4.851 1.00 50.34 ? 68 HIS A CG 1 ATOM 502 N ND1 . HIS A 1 68 ? 13.331 -33.585 -4.759 1.00 51.15 ? 68 HIS A ND1 1 ATOM 503 C CD2 . HIS A 1 68 ? 13.135 -31.416 -4.614 1.00 51.25 ? 68 HIS A CD2 1 ATOM 504 C CE1 . HIS A 1 68 ? 14.529 -33.104 -4.481 1.00 50.84 ? 68 HIS A CE1 1 ATOM 505 N NE2 . HIS A 1 68 ? 14.437 -31.791 -4.386 1.00 51.47 ? 68 HIS A NE2 1 ATOM 506 N N . PRO A 1 69 ? 12.231 -34.236 -7.985 1.00 54.94 ? 69 PRO A N 1 ATOM 507 C CA . PRO A 1 69 ? 12.635 -35.481 -8.672 1.00 55.94 ? 69 PRO A CA 1 ATOM 508 C C . PRO A 1 69 ? 12.838 -36.735 -7.800 1.00 57.86 ? 69 PRO A C 1 ATOM 509 O O . PRO A 1 69 ? 12.885 -37.841 -8.341 1.00 61.12 ? 69 PRO A O 1 ATOM 510 C CB . PRO A 1 69 ? 13.951 -35.099 -9.372 1.00 55.82 ? 69 PRO A CB 1 ATOM 511 C CG . PRO A 1 69 ? 14.400 -33.833 -8.740 1.00 55.78 ? 69 PRO A CG 1 ATOM 512 C CD . PRO A 1 69 ? 13.153 -33.130 -8.304 1.00 56.57 ? 69 PRO A CD 1 ATOM 513 N N . LYS A 1 70 ? 12.972 -36.561 -6.485 1.00 59.28 ? 70 LYS A N 1 ATOM 514 C CA . LYS A 1 70 ? 12.932 -37.666 -5.526 1.00 60.76 ? 70 LYS A CA 1 ATOM 515 C C . LYS A 1 70 ? 11.589 -37.740 -4.768 1.00 64.67 ? 70 LYS A C 1 ATOM 516 O O . LYS A 1 70 ? 11.558 -38.048 -3.570 1.00 65.77 ? 70 LYS A O 1 ATOM 517 C CB . LYS A 1 70 ? 14.114 -37.545 -4.559 1.00 58.06 ? 70 LYS A CB 1 ATOM 518 C CG . LYS A 1 70 ? 15.451 -37.631 -5.269 1.00 57.04 ? 70 LYS A CG 1 ATOM 519 C CD . LYS A 1 70 ? 16.596 -37.773 -4.290 1.00 57.17 ? 70 LYS A CD 1 ATOM 520 C CE . LYS A 1 70 ? 17.912 -37.945 -5.026 1.00 58.27 ? 70 LYS A CE 1 ATOM 521 N NZ . LYS A 1 70 ? 19.087 -38.009 -4.106 1.00 61.29 ? 70 LYS A NZ 1 ATOM 522 N N . GLN A 1 71 ? 10.492 -37.457 -5.479 1.00 68.05 ? 71 GLN A N 1 ATOM 523 C CA . GLN A 1 71 ? 9.121 -37.628 -4.971 1.00 70.49 ? 71 GLN A CA 1 ATOM 524 C C . GLN A 1 71 ? 8.180 -38.002 -6.127 1.00 71.46 ? 71 GLN A C 1 ATOM 525 O O . GLN A 1 71 ? 8.438 -37.652 -7.285 1.00 68.32 ? 71 GLN A O 1 ATOM 526 C CB . GLN A 1 71 ? 8.632 -36.362 -4.252 1.00 71.40 ? 71 GLN A CB 1 ATOM 527 C CG . GLN A 1 71 ? 9.308 -36.128 -2.906 1.00 73.40 ? 71 GLN A CG 1 ATOM 528 C CD . GLN A 1 71 ? 8.658 -35.039 -2.074 1.00 76.46 ? 71 GLN A CD 1 ATOM 529 O OE1 . GLN A 1 71 ? 8.464 -33.913 -2.542 1.00 79.85 ? 71 GLN A OE1 1 ATOM 530 N NE2 . GLN A 1 71 ? 8.344 -35.362 -0.820 1.00 76.49 ? 71 GLN A NE2 1 ATOM 531 N N . ARG A 1 72 ? 7.104 -38.722 -5.808 1.00 72.72 ? 72 ARG A N 1 ATOM 532 C CA . ARG A 1 72 ? 6.192 -39.253 -6.829 1.00 75.31 ? 72 ARG A CA 1 ATOM 533 C C . ARG A 1 72 ? 5.215 -38.167 -7.325 1.00 77.20 ? 72 ARG A C 1 ATOM 534 O O . ARG A 1 72 ? 4.778 -37.333 -6.524 1.00 80.96 ? 72 ARG A O 1 ATOM 535 C CB . ARG A 1 72 ? 5.416 -40.453 -6.270 1.00 74.64 ? 72 ARG A CB 1 ATOM 536 N N . PRO A 1 73 ? 4.877 -38.161 -8.641 1.00 75.40 ? 73 PRO A N 1 ATOM 537 C CA . PRO A 1 73 ? 3.852 -37.223 -9.142 1.00 75.33 ? 73 PRO A CA 1 ATOM 538 C C . PRO A 1 73 ? 2.428 -37.612 -8.737 1.00 77.50 ? 73 PRO A C 1 ATOM 539 O O . PRO A 1 73 ? 2.222 -38.673 -8.143 1.00 80.39 ? 73 PRO A O 1 ATOM 540 C CB . PRO A 1 73 ? 4.025 -37.281 -10.667 1.00 74.04 ? 73 PRO A CB 1 ATOM 541 C CG . PRO A 1 73 ? 4.656 -38.597 -10.935 1.00 73.40 ? 73 PRO A CG 1 ATOM 542 C CD . PRO A 1 73 ? 5.515 -38.909 -9.743 1.00 74.36 ? 73 PRO A CD 1 ATOM 543 N N . GLY A 1 74 ? 1.462 -36.748 -9.054 1.00 78.96 ? 74 GLY A N 1 ATOM 544 C CA . GLY A 1 74 ? 0.054 -36.967 -8.696 1.00 78.72 ? 74 GLY A CA 1 ATOM 545 C C . GLY A 1 74 ? -0.222 -36.819 -7.208 1.00 80.30 ? 74 GLY A C 1 ATOM 546 O O . GLY A 1 74 ? 0.468 -36.095 -6.489 1.00 81.87 ? 74 GLY A O 1 ATOM 547 O OXT . GLY A 1 74 ? -1.146 -37.427 -6.669 1.00 83.14 ? 74 GLY A OXT 1 ATOM 548 N N . LYS B 2 1 ? 44.088 -6.264 31.463 1.00 64.47 ? 0 LYS B N 1 ATOM 549 C CA . LYS B 2 1 ? 45.462 -6.789 31.758 1.00 64.96 ? 0 LYS B CA 1 ATOM 550 C C . LYS B 2 1 ? 45.774 -8.071 30.973 1.00 63.47 ? 0 LYS B C 1 ATOM 551 O O . LYS B 2 1 ? 44.926 -8.952 30.815 1.00 58.83 ? 0 LYS B O 1 ATOM 552 C CB . LYS B 2 1 ? 45.654 -7.012 33.268 1.00 66.80 ? 0 LYS B CB 1 ATOM 553 C CG . LYS B 2 1 ? 47.014 -7.584 33.680 1.00 68.97 ? 0 LYS B CG 1 ATOM 554 C CD . LYS B 2 1 ? 47.568 -6.942 34.949 1.00 70.89 ? 0 LYS B CD 1 ATOM 555 C CE . LYS B 2 1 ? 46.670 -7.133 36.166 1.00 71.34 ? 0 LYS B CE 1 ATOM 556 N NZ . LYS B 2 1 ? 47.255 -6.521 37.394 1.00 71.98 ? 0 LYS B NZ 1 ATOM 557 N N . SER B 2 2 ? 47.011 -8.144 30.493 1.00 63.44 ? 1 SER B N 1 ATOM 558 C CA . SER B 2 2 ? 47.510 -9.258 29.701 1.00 62.91 ? 1 SER B CA 1 ATOM 559 C C . SER B 2 2 ? 47.294 -10.620 30.366 1.00 60.81 ? 1 SER B C 1 ATOM 560 O O . SER B 2 2 ? 46.788 -11.544 29.728 1.00 58.22 ? 1 SER B O 1 ATOM 561 C CB . SER B 2 2 ? 49.001 -9.042 29.422 1.00 65.05 ? 1 SER B CB 1 ATOM 562 O OG . SER B 2 2 ? 49.525 -10.052 28.586 1.00 69.35 ? 1 SER B OG 1 ATOM 563 N N . GLU B 2 3 ? 47.669 -10.725 31.643 1.00 60.95 ? 2 GLU B N 1 ATOM 564 C CA . GLU B 2 3 ? 47.569 -11.980 32.411 1.00 62.44 ? 2 GLU B CA 1 ATOM 565 C C . GLU B 2 3 ? 46.159 -12.585 32.412 1.00 59.26 ? 2 GLU B C 1 ATOM 566 O O . GLU B 2 3 ? 46.004 -13.795 32.276 1.00 58.25 ? 2 GLU B O 1 ATOM 567 C CB . GLU B 2 3 ? 48.030 -11.760 33.863 1.00 68.80 ? 2 GLU B CB 1 ATOM 568 C CG . GLU B 2 3 ? 48.132 -13.027 34.723 1.00 73.11 ? 2 GLU B CG 1 ATOM 569 C CD . GLU B 2 3 ? 48.285 -12.730 36.212 1.00 77.34 ? 2 GLU B CD 1 ATOM 570 O OE1 . GLU B 2 3 ? 47.544 -13.337 37.033 1.00 74.17 ? 2 GLU B OE1 1 ATOM 571 O OE2 . GLU B 2 3 ? 49.146 -11.886 36.561 1.00 79.79 ? 2 GLU B OE2 1 ATOM 572 N N . HIS B 2 4 ? 45.142 -11.745 32.577 1.00 58.59 ? 3 HIS B N 1 ATOM 573 C CA . HIS B 2 4 ? 43.756 -12.218 32.613 1.00 57.88 ? 3 HIS B CA 1 ATOM 574 C C . HIS B 2 4 ? 43.271 -12.677 31.239 1.00 55.80 ? 3 HIS B C 1 ATOM 575 O O . HIS B 2 4 ? 42.552 -13.669 31.139 1.00 57.26 ? 3 HIS B O 1 ATOM 576 C CB . HIS B 2 4 ? 42.814 -11.145 33.179 1.00 59.02 ? 3 HIS B CB 1 ATOM 577 C CG . HIS B 2 4 ? 43.099 -10.783 34.604 1.00 59.87 ? 3 HIS B CG 1 ATOM 578 N ND1 . HIS B 2 4 ? 43.395 -11.725 35.567 1.00 61.54 ? 3 HIS B ND1 1 ATOM 579 C CD2 . HIS B 2 4 ? 43.131 -9.583 35.229 1.00 57.98 ? 3 HIS B CD2 1 ATOM 580 C CE1 . HIS B 2 4 ? 43.608 -11.119 36.721 1.00 60.35 ? 3 HIS B CE1 1 ATOM 581 N NE2 . HIS B 2 4 ? 43.454 -9.820 36.542 1.00 58.67 ? 3 HIS B NE2 1 ATOM 582 N N . GLU B 2 5 ? 43.667 -11.963 30.190 1.00 53.47 ? 4 GLU B N 1 ATOM 583 C CA . GLU B 2 5 ? 43.260 -12.314 28.829 1.00 52.41 ? 4 GLU B CA 1 ATOM 584 C C . GLU B 2 5 ? 43.945 -13.591 28.359 1.00 48.80 ? 4 GLU B C 1 ATOM 585 O O . GLU B 2 5 ? 43.347 -14.386 27.642 1.00 46.57 ? 4 GLU B O 1 ATOM 586 C CB . GLU B 2 5 ? 43.537 -11.163 27.869 1.00 54.36 ? 4 GLU B CB 1 ATOM 587 C CG . GLU B 2 5 ? 42.707 -9.929 28.180 1.00 57.39 ? 4 GLU B CG 1 ATOM 588 C CD . GLU B 2 5 ? 42.978 -8.768 27.243 1.00 60.71 ? 4 GLU B CD 1 ATOM 589 O OE1 . GLU B 2 5 ? 44.161 -8.523 26.907 1.00 62.57 ? 4 GLU B OE1 1 ATOM 590 O OE2 . GLU B 2 5 ? 41.997 -8.090 26.854 1.00 64.11 ? 4 GLU B OE2 1 ATOM 591 N N . THR B 2 6 ? 45.195 -13.781 28.771 1.00 46.83 ? 5 THR B N 1 ATOM 592 C CA . THR B 2 6 ? 45.896 -15.044 28.553 1.00 46.92 ? 5 THR B CA 1 ATOM 593 C C . THR B 2 6 ? 45.121 -16.206 29.183 1.00 47.06 ? 5 THR B C 1 ATOM 594 O O . THR B 2 6 ? 44.758 -17.156 28.484 1.00 48.24 ? 5 THR B O 1 ATOM 595 C CB . THR B 2 6 ? 47.334 -14.988 29.115 1.00 46.43 ? 5 THR B CB 1 ATOM 596 O OG1 . THR B 2 6 ? 48.102 -14.052 28.349 1.00 45.60 ? 5 THR B OG1 1 ATOM 597 C CG2 . THR B 2 6 ? 48.020 -16.358 29.078 1.00 45.39 ? 5 THR B CG2 1 ATOM 598 N N . ARG B 2 7 ? 44.854 -16.114 30.487 1.00 45.72 ? 6 ARG B N 1 ATOM 599 C CA . ARG B 2 7 ? 44.103 -17.157 31.199 1.00 46.00 ? 6 ARG B CA 1 ATOM 600 C C . ARG B 2 7 ? 42.717 -17.401 30.576 1.00 44.67 ? 6 ARG B C 1 ATOM 601 O O . ARG B 2 7 ? 42.283 -18.557 30.427 1.00 42.19 ? 6 ARG B O 1 ATOM 602 C CB . ARG B 2 7 ? 43.957 -16.822 32.693 1.00 46.27 ? 6 ARG B CB 1 ATOM 603 C CG . ARG B 2 7 ? 43.367 -17.977 33.500 1.00 48.00 ? 6 ARG B CG 1 ATOM 604 C CD . ARG B 2 7 ? 43.372 -17.748 35.002 1.00 49.47 ? 6 ARG B CD 1 ATOM 605 N NE . ARG B 2 7 ? 44.712 -17.453 35.510 1.00 49.17 ? 6 ARG B NE 1 ATOM 606 C CZ . ARG B 2 7 ? 45.160 -16.253 35.883 1.00 51.05 ? 6 ARG B CZ 1 ATOM 607 N NH1 . ARG B 2 7 ? 44.394 -15.156 35.839 1.00 51.84 ? 6 ARG B NH1 1 ATOM 608 N NH2 . ARG B 2 7 ? 46.412 -16.149 36.313 1.00 51.86 ? 6 ARG B NH2 1 ATOM 609 N N . LEU B 2 8 ? 42.045 -16.308 30.219 1.00 42.69 ? 7 LEU B N 1 ATOM 610 C CA . LEU B 2 8 ? 40.720 -16.359 29.617 1.00 42.15 ? 7 LEU B CA 1 ATOM 611 C C . LEU B 2 8 ? 40.716 -17.205 28.351 1.00 43.40 ? 7 LEU B C 1 ATOM 612 O O . LEU B 2 8 ? 39.853 -18.070 28.184 1.00 43.42 ? 7 LEU B O 1 ATOM 613 C CB . LEU B 2 8 ? 40.224 -14.950 29.303 1.00 40.52 ? 7 LEU B CB 1 ATOM 614 C CG . LEU B 2 8 ? 38.851 -14.802 28.657 1.00 40.72 ? 7 LEU B CG 1 ATOM 615 C CD1 . LEU B 2 8 ? 37.775 -15.472 29.487 1.00 40.26 ? 7 LEU B CD1 1 ATOM 616 C CD2 . LEU B 2 8 ? 38.525 -13.328 28.467 1.00 41.67 ? 7 LEU B CD2 1 ATOM 617 N N . GLU B 2 9 ? 41.692 -16.970 27.479 1.00 45.03 ? 8 GLU B N 1 ATOM 618 C CA . GLU B 2 9 ? 41.773 -17.704 26.214 1.00 46.06 ? 8 GLU B CA 1 ATOM 619 C C . GLU B 2 9 ? 42.058 -19.190 26.459 1.00 46.78 ? 8 GLU B C 1 ATOM 620 O O . GLU B 2 9 ? 41.466 -20.052 25.808 1.00 46.10 ? 8 GLU B O 1 ATOM 621 C CB . GLU B 2 9 ? 42.821 -17.091 25.279 1.00 46.44 ? 8 GLU B CB 1 ATOM 622 C CG . GLU B 2 9 ? 42.574 -17.412 23.812 1.00 48.29 ? 8 GLU B CG 1 ATOM 623 C CD . GLU B 2 9 ? 43.605 -16.811 22.866 1.00 50.19 ? 8 GLU B CD 1 ATOM 624 O OE1 . GLU B 2 9 ? 44.248 -15.789 23.203 1.00 51.68 ? 8 GLU B OE1 1 ATOM 625 O OE2 . GLU B 2 9 ? 43.766 -17.366 21.760 1.00 51.38 ? 8 GLU B OE2 1 ATOM 626 N N . ALA B 2 10 ? 42.939 -19.481 27.415 1.00 46.37 ? 9 ALA B N 1 ATOM 627 C CA . ALA B 2 10 ? 43.244 -20.862 27.793 1.00 46.92 ? 9 ALA B CA 1 ATOM 628 C C . ALA B 2 10 ? 41.997 -21.594 28.337 1.00 48.85 ? 9 ALA B C 1 ATOM 629 O O . ALA B 2 10 ? 41.635 -22.673 27.846 1.00 46.90 ? 9 ALA B O 1 ATOM 630 C CB . ALA B 2 10 ? 44.370 -20.883 28.817 1.00 46.09 ? 9 ALA B CB 1 ATOM 631 N N . LYS B 2 11 ? 41.345 -20.984 29.329 1.00 48.75 ? 10 LYS B N 1 ATOM 632 C CA . LYS B 2 11 ? 40.130 -21.543 29.945 1.00 48.13 ? 10 LYS B CA 1 ATOM 633 C C . LYS B 2 11 ? 39.007 -21.801 28.947 1.00 46.62 ? 10 LYS B C 1 ATOM 634 O O . LYS B 2 11 ? 38.312 -22.811 29.037 1.00 45.25 ? 10 LYS B O 1 ATOM 635 C CB . LYS B 2 11 ? 39.597 -20.620 31.055 1.00 50.61 ? 10 LYS B CB 1 ATOM 636 C CG . LYS B 2 11 ? 39.808 -21.132 32.472 1.00 51.41 ? 10 LYS B CG 1 ATOM 637 C CD . LYS B 2 11 ? 41.267 -21.227 32.882 1.00 51.78 ? 10 LYS B CD 1 ATOM 638 C CE . LYS B 2 11 ? 41.390 -21.078 34.393 1.00 53.78 ? 10 LYS B CE 1 ATOM 639 N NZ . LYS B 2 11 ? 42.626 -21.680 34.952 1.00 56.23 ? 10 LYS B NZ 1 ATOM 640 N N . LEU B 2 12 ? 38.819 -20.868 28.018 1.00 46.80 ? 11 LEU B N 1 ATOM 641 C CA . LEU B 2 12 ? 37.761 -20.980 27.005 1.00 46.04 ? 11 LEU B CA 1 ATOM 642 C C . LEU B 2 12 ? 37.984 -22.137 26.042 1.00 46.09 ? 11 LEU B C 1 ATOM 643 O O . LEU B 2 12 ? 37.024 -22.722 25.556 1.00 45.57 ? 11 LEU B O 1 ATOM 644 C CB . LEU B 2 12 ? 37.650 -19.687 26.188 1.00 45.08 ? 11 LEU B CB 1 ATOM 645 C CG . LEU B 2 12 ? 37.022 -18.457 26.844 1.00 43.82 ? 11 LEU B CG 1 ATOM 646 C CD1 . LEU B 2 12 ? 37.442 -17.192 26.103 1.00 43.29 ? 11 LEU B CD1 1 ATOM 647 C CD2 . LEU B 2 12 ? 35.506 -18.582 26.885 1.00 43.72 ? 11 LEU B CD2 1 ATOM 648 N N . PHE B 2 13 ? 39.249 -22.444 25.765 1.00 47.72 ? 12 PHE B N 1 ATOM 649 C CA . PHE B 2 13 ? 39.619 -23.376 24.705 1.00 49.18 ? 12 PHE B CA 1 ATOM 650 C C . PHE B 2 13 ? 40.165 -24.722 25.167 1.00 51.72 ? 12 PHE B C 1 ATOM 651 O O . PHE B 2 13 ? 40.378 -25.592 24.323 1.00 52.35 ? 12 PHE B O 1 ATOM 652 C CB . PHE B 2 13 ? 40.600 -22.695 23.739 1.00 48.92 ? 12 PHE B CB 1 ATOM 653 C CG . PHE B 2 13 ? 39.930 -21.745 22.785 1.00 47.74 ? 12 PHE B CG 1 ATOM 654 C CD1 . PHE B 2 13 ? 39.159 -22.238 21.743 1.00 48.47 ? 12 PHE B CD1 1 ATOM 655 C CD2 . PHE B 2 13 ? 40.048 -20.372 22.936 1.00 46.63 ? 12 PHE B CD2 1 ATOM 656 C CE1 . PHE B 2 13 ? 38.526 -21.380 20.863 1.00 50.83 ? 12 PHE B CE1 1 ATOM 657 C CE2 . PHE B 2 13 ? 39.420 -19.505 22.061 1.00 48.47 ? 12 PHE B CE2 1 ATOM 658 C CZ . PHE B 2 13 ? 38.655 -20.007 21.023 1.00 50.72 ? 12 PHE B CZ 1 ATOM 659 N N . GLU B 2 14 ? 40.375 -24.909 26.475 1.00 54.32 ? 13 GLU B N 1 ATOM 660 C CA . GLU B 2 14 ? 40.816 -26.206 27.010 1.00 55.18 ? 13 GLU B CA 1 ATOM 661 C C . GLU B 2 14 ? 39.931 -27.332 26.512 1.00 52.44 ? 13 GLU B C 1 ATOM 662 O O . GLU B 2 14 ? 40.428 -28.297 25.935 1.00 54.99 ? 13 GLU B O 1 ATOM 663 C CB . GLU B 2 14 ? 40.815 -26.231 28.543 1.00 60.57 ? 13 GLU B CB 1 ATOM 664 C CG . GLU B 2 14 ? 42.136 -25.848 29.191 1.00 66.24 ? 13 GLU B CG 1 ATOM 665 C CD . GLU B 2 14 ? 42.075 -25.923 30.711 1.00 72.04 ? 13 GLU B CD 1 ATOM 666 O OE1 . GLU B 2 14 ? 41.627 -26.971 31.234 1.00 73.18 ? 13 GLU B OE1 1 ATOM 667 O OE2 . GLU B 2 14 ? 42.474 -24.938 31.384 1.00 76.26 ? 13 GLU B OE2 1 ATOM 668 N N . ASP B 2 15 ? 38.626 -27.190 26.734 1.00 49.59 ? 14 ASP B N 1 ATOM 669 C CA . ASP B 2 15 ? 37.641 -28.210 26.359 1.00 50.23 ? 14 ASP B CA 1 ATOM 670 C C . ASP B 2 15 ? 36.713 -27.765 25.217 1.00 47.99 ? 14 ASP B C 1 ATOM 671 O O . ASP B 2 15 ? 35.564 -28.203 25.138 1.00 47.34 ? 14 ASP B O 1 ATOM 672 C CB . ASP B 2 15 ? 36.811 -28.596 27.586 1.00 53.33 ? 14 ASP B CB 1 ATOM 673 C CG . ASP B 2 15 ? 37.641 -29.236 28.666 1.00 55.56 ? 14 ASP B CG 1 ATOM 674 O OD1 . ASP B 2 15 ? 38.232 -30.303 28.393 1.00 61.94 ? 14 ASP B OD1 1 ATOM 675 O OD2 . ASP B 2 15 ? 37.695 -28.678 29.782 1.00 55.88 ? 14 ASP B OD2 1 ATOM 676 N N . TYR B 2 16 ? 37.218 -26.922 24.322 1.00 44.09 ? 15 TYR B N 1 ATOM 677 C CA . TYR B 2 16 ? 36.427 -26.424 23.211 1.00 43.06 ? 15 TYR B CA 1 ATOM 678 C C . TYR B 2 16 ? 36.582 -27.356 22.024 1.00 42.94 ? 15 TYR B C 1 ATOM 679 O O . TYR B 2 16 ? 37.634 -27.969 21.856 1.00 42.83 ? 15 TYR B O 1 ATOM 680 C CB . TYR B 2 16 ? 36.886 -25.018 22.828 1.00 41.83 ? 15 TYR B CB 1 ATOM 681 C CG . TYR B 2 16 ? 36.022 -24.351 21.789 1.00 39.58 ? 15 TYR B CG 1 ATOM 682 C CD1 . TYR B 2 16 ? 34.803 -23.774 22.139 1.00 39.44 ? 15 TYR B CD1 1 ATOM 683 C CD2 . TYR B 2 16 ? 36.410 -24.301 20.461 1.00 38.09 ? 15 TYR B CD2 1 ATOM 684 C CE1 . TYR B 2 16 ? 33.998 -23.160 21.191 1.00 38.17 ? 15 TYR B CE1 1 ATOM 685 C CE2 . TYR B 2 16 ? 35.613 -23.683 19.507 1.00 37.86 ? 15 TYR B CE2 1 ATOM 686 C CZ . TYR B 2 16 ? 34.409 -23.116 19.879 1.00 36.89 ? 15 TYR B CZ 1 ATOM 687 O OH . TYR B 2 16 ? 33.611 -22.511 18.947 1.00 35.87 ? 15 TYR B OH 1 ATOM 688 N N . SER B 2 17 ? 35.531 -27.448 21.210 1.00 43.49 ? 16 SER B N 1 ATOM 689 C CA . SER B 2 17 ? 35.582 -28.127 19.913 1.00 44.82 ? 16 SER B CA 1 ATOM 690 C C . SER B 2 17 ? 35.065 -27.207 18.783 1.00 44.15 ? 16 SER B C 1 ATOM 691 O O . SER B 2 17 ? 33.895 -26.792 18.779 1.00 42.72 ? 16 SER B O 1 ATOM 692 C CB . SER B 2 17 ? 34.768 -29.419 19.953 1.00 45.78 ? 16 SER B CB 1 ATOM 693 O OG . SER B 2 17 ? 34.832 -30.099 18.706 1.00 49.55 ? 16 SER B OG 1 ATOM 694 N N . SER B 2 18 ? 35.935 -26.917 17.815 1.00 42.27 ? 17 SER B N 1 ATOM 695 C CA . SER B 2 18 ? 35.554 -26.120 16.651 1.00 43.74 ? 17 SER B CA 1 ATOM 696 C C . SER B 2 18 ? 34.735 -26.900 15.614 1.00 44.00 ? 17 SER B C 1 ATOM 697 O O . SER B 2 18 ? 34.256 -26.309 14.641 1.00 44.67 ? 17 SER B O 1 ATOM 698 C CB . SER B 2 18 ? 36.796 -25.509 15.992 1.00 44.17 ? 17 SER B CB 1 ATOM 699 O OG . SER B 2 18 ? 37.752 -26.499 15.687 1.00 44.64 ? 17 SER B OG 1 ATOM 700 N N . VAL B 2 19 ? 34.565 -28.206 15.821 1.00 44.52 ? 18 VAL B N 1 ATOM 701 C CA . VAL B 2 19 ? 33.863 -29.073 14.870 1.00 46.05 ? 18 VAL B CA 1 ATOM 702 C C . VAL B 2 19 ? 32.334 -29.097 15.078 1.00 47.15 ? 18 VAL B C 1 ATOM 703 O O . VAL B 2 19 ? 31.581 -29.188 14.108 1.00 48.45 ? 18 VAL B O 1 ATOM 704 C CB . VAL B 2 19 ? 34.470 -30.497 14.914 1.00 45.56 ? 18 VAL B CB 1 ATOM 705 C CG1 . VAL B 2 19 ? 33.662 -31.489 14.079 1.00 46.40 ? 18 VAL B CG1 1 ATOM 706 C CG2 . VAL B 2 19 ? 35.919 -30.440 14.444 1.00 44.60 ? 18 VAL B CG2 1 ATOM 707 N N . VAL B 2 20 ? 31.881 -29.025 16.327 1.00 47.63 ? 19 VAL B N 1 ATOM 708 C CA . VAL B 2 20 ? 30.442 -29.102 16.639 1.00 48.47 ? 19 VAL B CA 1 ATOM 709 C C . VAL B 2 20 ? 29.744 -27.736 16.585 1.00 46.71 ? 19 VAL B C 1 ATOM 710 O O . VAL B 2 20 ? 30.326 -26.725 16.974 1.00 48.95 ? 19 VAL B O 1 ATOM 711 C CB . VAL B 2 20 ? 30.193 -29.760 18.025 1.00 50.96 ? 19 VAL B CB 1 ATOM 712 C CG1 . VAL B 2 20 ? 30.886 -31.118 18.101 1.00 51.02 ? 19 VAL B CG1 1 ATOM 713 C CG2 . VAL B 2 20 ? 30.625 -28.856 19.184 1.00 51.83 ? 19 VAL B CG2 1 ATOM 714 N N . ARG B 2 21 ? 28.499 -27.711 16.110 1.00 45.08 ? 20 ARG B N 1 ATOM 715 C CA . ARG B 2 21 ? 27.678 -26.494 16.154 1.00 44.12 ? 20 ARG B CA 1 ATOM 716 C C . ARG B 2 21 ? 27.485 -26.079 17.612 1.00 44.19 ? 20 ARG B C 1 ATOM 717 O O . ARG B 2 21 ? 27.245 -26.940 18.456 1.00 45.00 ? 20 ARG B O 1 ATOM 718 C CB . ARG B 2 21 ? 26.308 -26.710 15.497 1.00 42.90 ? 20 ARG B CB 1 ATOM 719 C CG . ARG B 2 21 ? 26.369 -26.908 13.995 1.00 44.17 ? 20 ARG B CG 1 ATOM 720 C CD . ARG B 2 21 ? 24.989 -26.918 13.347 1.00 45.63 ? 20 ARG B CD 1 ATOM 721 N NE . ARG B 2 21 ? 24.112 -27.959 13.908 1.00 46.57 ? 20 ARG B NE 1 ATOM 722 C CZ . ARG B 2 21 ? 22.867 -27.787 14.372 1.00 46.68 ? 20 ARG B CZ 1 ATOM 723 N NH1 . ARG B 2 21 ? 22.258 -26.603 14.353 1.00 47.62 ? 20 ARG B NH1 1 ATOM 724 N NH2 . ARG B 2 21 ? 22.206 -28.831 14.860 1.00 46.36 ? 20 ARG B NH2 1 ATOM 725 N N . PRO B 2 22 ? 27.596 -24.770 17.923 1.00 44.91 ? 21 PRO B N 1 ATOM 726 C CA . PRO B 2 22 ? 27.455 -24.329 19.314 1.00 46.28 ? 21 PRO B CA 1 ATOM 727 C C . PRO B 2 22 ? 25.991 -24.259 19.763 1.00 47.60 ? 21 PRO B C 1 ATOM 728 O O . PRO B 2 22 ? 25.424 -23.176 19.920 1.00 46.60 ? 21 PRO B O 1 ATOM 729 C CB . PRO B 2 22 ? 28.134 -22.957 19.307 1.00 46.24 ? 21 PRO B CB 1 ATOM 730 C CG . PRO B 2 22 ? 27.884 -22.444 17.937 1.00 46.46 ? 21 PRO B CG 1 ATOM 731 C CD . PRO B 2 22 ? 27.956 -23.648 17.037 1.00 45.03 ? 21 PRO B CD 1 ATOM 732 N N . VAL B 2 23 ? 25.415 -25.437 19.979 1.00 51.00 ? 22 VAL B N 1 ATOM 733 C CA . VAL B 2 23 ? 24.027 -25.600 20.397 1.00 55.73 ? 22 VAL B CA 1 ATOM 734 C C . VAL B 2 23 ? 23.952 -26.675 21.474 1.00 61.35 ? 22 VAL B C 1 ATOM 735 O O . VAL B 2 23 ? 24.749 -27.615 21.476 1.00 63.91 ? 22 VAL B O 1 ATOM 736 C CB . VAL B 2 23 ? 23.102 -25.991 19.219 1.00 55.85 ? 22 VAL B CB 1 ATOM 737 C CG1 . VAL B 2 23 ? 22.943 -24.824 18.258 1.00 55.89 ? 22 VAL B CG1 1 ATOM 738 C CG2 . VAL B 2 23 ? 23.603 -27.233 18.479 1.00 55.20 ? 22 VAL B CG2 1 ATOM 739 N N . GLU B 2 24 ? 22.977 -26.541 22.367 1.00 67.99 ? 23 GLU B N 1 ATOM 740 C CA . GLU B 2 24 ? 22.838 -27.445 23.511 1.00 70.68 ? 23 GLU B CA 1 ATOM 741 C C . GLU B 2 24 ? 22.123 -28.726 23.062 1.00 71.93 ? 23 GLU B C 1 ATOM 742 O O . GLU B 2 24 ? 22.597 -29.829 23.336 1.00 75.93 ? 23 GLU B O 1 ATOM 743 C CB . GLU B 2 24 ? 22.093 -26.744 24.662 1.00 74.78 ? 23 GLU B CB 1 ATOM 744 C CG . GLU B 2 24 ? 22.800 -26.814 26.015 1.00 77.37 ? 23 GLU B CG 1 ATOM 745 C CD . GLU B 2 24 ? 22.363 -25.709 26.969 1.00 79.09 ? 23 GLU B CD 1 ATOM 746 O OE1 . GLU B 2 24 ? 21.176 -25.317 26.935 1.00 81.99 ? 23 GLU B OE1 1 ATOM 747 O OE2 . GLU B 2 24 ? 23.211 -25.226 27.752 1.00 79.44 ? 23 GLU B OE2 1 ATOM 748 N N . ASP B 2 25 ? 20.993 -28.564 22.371 1.00 71.23 ? 24 ASP B N 1 ATOM 749 C CA . ASP B 2 25 ? 20.270 -29.666 21.720 1.00 71.83 ? 24 ASP B CA 1 ATOM 750 C C . ASP B 2 25 ? 20.562 -29.584 20.223 1.00 72.64 ? 24 ASP B C 1 ATOM 751 O O . ASP B 2 25 ? 20.503 -28.500 19.647 1.00 74.18 ? 24 ASP B O 1 ATOM 752 C CB . ASP B 2 25 ? 18.762 -29.525 21.980 1.00 72.84 ? 24 ASP B CB 1 ATOM 753 C CG . ASP B 2 25 ? 17.957 -30.778 21.602 1.00 74.30 ? 24 ASP B CG 1 ATOM 754 O OD1 . ASP B 2 25 ? 18.205 -31.391 20.539 1.00 70.54 ? 24 ASP B OD1 1 ATOM 755 O OD2 . ASP B 2 25 ? 17.041 -31.138 22.376 1.00 76.92 ? 24 ASP B OD2 1 ATOM 756 N N . HIS B 2 26 ? 20.837 -30.726 19.589 1.00 74.90 ? 25 HIS B N 1 ATOM 757 C CA . HIS B 2 26 ? 21.193 -30.757 18.155 1.00 76.30 ? 25 HIS B CA 1 ATOM 758 C C . HIS B 2 26 ? 20.026 -30.407 17.202 1.00 74.65 ? 25 HIS B C 1 ATOM 759 O O . HIS B 2 26 ? 20.239 -30.262 15.998 1.00 76.43 ? 25 HIS B O 1 ATOM 760 C CB . HIS B 2 26 ? 21.841 -32.103 17.764 1.00 79.66 ? 25 HIS B CB 1 ATOM 761 C CG . HIS B 2 26 ? 20.875 -33.132 17.254 1.00 85.09 ? 25 HIS B CG 1 ATOM 762 N ND1 . HIS B 2 26 ? 19.855 -33.648 18.026 1.00 86.25 ? 25 HIS B ND1 1 ATOM 763 C CD2 . HIS B 2 26 ? 20.782 -33.745 16.049 1.00 87.58 ? 25 HIS B CD2 1 ATOM 764 C CE1 . HIS B 2 26 ? 19.172 -34.530 17.317 1.00 86.25 ? 25 HIS B CE1 1 ATOM 765 N NE2 . HIS B 2 26 ? 19.714 -34.607 16.114 1.00 88.28 ? 25 HIS B NE2 1 ATOM 766 N N . ARG B 2 27 ? 18.808 -30.303 17.734 1.00 71.49 ? 26 ARG B N 1 ATOM 767 C CA . ARG B 2 27 ? 17.657 -29.797 16.976 1.00 70.88 ? 26 ARG B CA 1 ATOM 768 C C . ARG B 2 27 ? 17.653 -28.263 16.830 1.00 68.36 ? 26 ARG B C 1 ATOM 769 O O . ARG B 2 27 ? 17.032 -27.746 15.897 1.00 66.76 ? 26 ARG B O 1 ATOM 770 C CB . ARG B 2 27 ? 16.342 -30.275 17.619 1.00 73.48 ? 26 ARG B CB 1 ATOM 771 C CG . ARG B 2 27 ? 15.953 -31.713 17.270 1.00 74.61 ? 26 ARG B CG 1 ATOM 772 C CD . ARG B 2 27 ? 15.726 -32.599 18.493 1.00 77.42 ? 26 ARG B CD 1 ATOM 773 N NE . ARG B 2 27 ? 14.854 -32.002 19.509 1.00 79.96 ? 26 ARG B NE 1 ATOM 774 C CZ . ARG B 2 27 ? 14.499 -32.591 20.654 1.00 80.49 ? 26 ARG B CZ 1 ATOM 775 N NH1 . ARG B 2 27 ? 14.918 -33.821 20.957 1.00 81.95 ? 26 ARG B NH1 1 ATOM 776 N NH2 . ARG B 2 27 ? 13.707 -31.946 21.505 1.00 80.20 ? 26 ARG B NH2 1 ATOM 777 N N . GLU B 2 28 ? 18.321 -27.544 17.741 1.00 65.28 ? 27 GLU B N 1 ATOM 778 C CA . GLU B 2 28 ? 18.489 -26.084 17.616 1.00 63.09 ? 27 GLU B CA 1 ATOM 779 C C . GLU B 2 28 ? 19.178 -25.693 16.306 1.00 57.98 ? 27 GLU B C 1 ATOM 780 O O . GLU B 2 28 ? 20.175 -26.304 15.909 1.00 55.06 ? 27 GLU B O 1 ATOM 781 C CB . GLU B 2 28 ? 19.341 -25.511 18.753 1.00 66.63 ? 27 GLU B CB 1 ATOM 782 C CG . GLU B 2 28 ? 18.695 -25.465 20.122 1.00 71.42 ? 27 GLU B CG 1 ATOM 783 C CD . GLU B 2 28 ? 19.562 -24.726 21.132 1.00 75.91 ? 27 GLU B CD 1 ATOM 784 O OE1 . GLU B 2 28 ? 19.981 -25.349 22.135 1.00 78.27 ? 27 GLU B OE1 1 ATOM 785 O OE2 . GLU B 2 28 ? 19.840 -23.523 20.915 1.00 77.37 ? 27 GLU B OE2 1 ATOM 786 N N . ILE B 2 29 ? 18.649 -24.655 15.666 1.00 53.36 ? 28 ILE B N 1 ATOM 787 C CA . ILE B 2 29 ? 19.237 -24.069 14.467 1.00 50.43 ? 28 ILE B CA 1 ATOM 788 C C . ILE B 2 29 ? 20.073 -22.867 14.901 1.00 47.61 ? 28 ILE B C 1 ATOM 789 O O . ILE B 2 29 ? 19.562 -22.002 15.616 1.00 49.24 ? 28 ILE B O 1 ATOM 790 C CB . ILE B 2 29 ? 18.134 -23.604 13.489 1.00 50.94 ? 28 ILE B CB 1 ATOM 791 C CG1 . ILE B 2 29 ? 17.254 -24.799 13.082 1.00 49.84 ? 28 ILE B CG1 1 ATOM 792 C CG2 . ILE B 2 29 ? 18.744 -22.899 12.270 1.00 51.21 ? 28 ILE B CG2 1 ATOM 793 C CD1 . ILE B 2 29 ? 16.017 -24.432 12.289 1.00 50.28 ? 28 ILE B CD1 1 ATOM 794 N N . VAL B 2 30 ? 21.341 -22.810 14.479 1.00 43.50 ? 29 VAL B N 1 ATOM 795 C CA . VAL B 2 30 ? 22.215 -21.679 14.814 1.00 41.20 ? 29 VAL B CA 1 ATOM 796 C C . VAL B 2 30 ? 21.793 -20.472 13.988 1.00 39.47 ? 29 VAL B C 1 ATOM 797 O O . VAL B 2 30 ? 21.701 -20.574 12.772 1.00 40.40 ? 29 VAL B O 1 ATOM 798 C CB . VAL B 2 30 ? 23.704 -21.978 14.540 1.00 41.56 ? 29 VAL B CB 1 ATOM 799 C CG1 . VAL B 2 30 ? 24.562 -20.728 14.762 1.00 42.02 ? 29 VAL B CG1 1 ATOM 800 C CG2 . VAL B 2 30 ? 24.199 -23.111 15.427 1.00 41.86 ? 29 VAL B CG2 1 ATOM 801 N N . GLN B 2 31 ? 21.538 -19.341 14.643 1.00 38.20 ? 30 GLN B N 1 ATOM 802 C CA . GLN B 2 31 ? 21.173 -18.109 13.939 1.00 38.24 ? 30 GLN B CA 1 ATOM 803 C C . GLN B 2 31 ? 22.421 -17.287 13.656 1.00 38.89 ? 30 GLN B C 1 ATOM 804 O O . GLN B 2 31 ? 23.128 -16.887 14.594 1.00 39.34 ? 30 GLN B O 1 ATOM 805 C CB . GLN B 2 31 ? 20.195 -17.272 14.760 1.00 38.27 ? 30 GLN B CB 1 ATOM 806 C CG . GLN B 2 31 ? 18.894 -17.980 15.103 1.00 38.83 ? 30 GLN B CG 1 ATOM 807 C CD . GLN B 2 31 ? 18.104 -18.396 13.882 1.00 38.86 ? 30 GLN B CD 1 ATOM 808 O OE1 . GLN B 2 31 ? 17.729 -17.565 13.056 1.00 40.33 ? 30 GLN B OE1 1 ATOM 809 N NE2 . GLN B 2 31 ? 17.852 -19.692 13.757 1.00 39.37 ? 30 GLN B NE2 1 ATOM 810 N N . VAL B 2 32 ? 22.695 -17.052 12.369 1.00 37.13 ? 31 VAL B N 1 ATOM 811 C CA . VAL B 2 32 ? 23.815 -16.224 11.939 1.00 37.46 ? 31 VAL B CA 1 ATOM 812 C C . VAL B 2 32 ? 23.248 -14.986 11.249 1.00 38.90 ? 31 VAL B C 1 ATOM 813 O O . VAL B 2 32 ? 22.464 -15.105 10.304 1.00 40.07 ? 31 VAL B O 1 ATOM 814 C CB . VAL B 2 32 ? 24.744 -16.996 10.979 1.00 37.85 ? 31 VAL B CB 1 ATOM 815 C CG1 . VAL B 2 32 ? 25.825 -16.092 10.402 1.00 38.43 ? 31 VAL B CG1 1 ATOM 816 C CG2 . VAL B 2 32 ? 25.392 -18.171 11.688 1.00 38.18 ? 31 VAL B CG2 1 ATOM 817 N N . THR B 2 33 ? 23.632 -13.803 11.726 1.00 39.89 ? 32 THR B N 1 ATOM 818 C CA . THR B 2 33 ? 23.214 -12.548 11.107 1.00 40.51 ? 32 THR B CA 1 ATOM 819 C C . THR B 2 33 ? 24.272 -12.146 10.097 1.00 41.42 ? 32 THR B C 1 ATOM 820 O O . THR B 2 33 ? 25.425 -11.923 10.467 1.00 42.32 ? 32 THR B O 1 ATOM 821 C CB . THR B 2 33 ? 23.018 -11.433 12.148 1.00 39.59 ? 32 THR B CB 1 ATOM 822 O OG1 . THR B 2 33 ? 21.997 -11.831 13.063 1.00 40.18 ? 32 THR B OG1 1 ATOM 823 C CG2 . THR B 2 33 ? 22.600 -10.127 11.492 1.00 39.43 ? 32 THR B CG2 1 ATOM 824 N N . VAL B 2 34 ? 23.869 -12.058 8.829 1.00 41.87 ? 33 VAL B N 1 ATOM 825 C CA . VAL B 2 34 ? 24.790 -11.822 7.725 1.00 43.38 ? 33 VAL B CA 1 ATOM 826 C C . VAL B 2 34 ? 24.557 -10.436 7.146 1.00 43.88 ? 33 VAL B C 1 ATOM 827 O O . VAL B 2 34 ? 23.436 -9.955 7.090 1.00 45.23 ? 33 VAL B O 1 ATOM 828 C CB . VAL B 2 34 ? 24.630 -12.879 6.611 1.00 45.43 ? 33 VAL B CB 1 ATOM 829 C CG1 . VAL B 2 34 ? 25.676 -12.677 5.518 1.00 47.98 ? 33 VAL B CG1 1 ATOM 830 C CG2 . VAL B 2 34 ? 24.760 -14.286 7.181 1.00 46.61 ? 33 VAL B CG2 1 ATOM 831 N N . GLY B 2 35 ? 25.640 -9.796 6.730 1.00 45.25 ? 34 GLY B N 1 ATOM 832 C CA . GLY B 2 35 ? 25.580 -8.510 6.059 1.00 45.49 ? 34 GLY B CA 1 ATOM 833 C C . GLY B 2 35 ? 26.773 -8.359 5.138 1.00 46.58 ? 34 GLY B C 1 ATOM 834 O O . GLY B 2 35 ? 27.902 -8.669 5.531 1.00 48.32 ? 34 GLY B O 1 ATOM 835 N N . LEU B 2 36 ? 26.521 -7.893 3.916 1.00 46.99 ? 35 LEU B N 1 ATOM 836 C CA . LEU B 2 36 ? 27.584 -7.586 2.964 1.00 48.11 ? 35 LEU B CA 1 ATOM 837 C C . LEU B 2 36 ? 27.936 -6.095 3.017 1.00 46.83 ? 35 LEU B C 1 ATOM 838 O O . LEU B 2 36 ? 27.059 -5.251 2.864 1.00 46.70 ? 35 LEU B O 1 ATOM 839 C CB . LEU B 2 36 ? 27.132 -7.960 1.557 1.00 49.30 ? 35 LEU B CB 1 ATOM 840 C CG . LEU B 2 36 ? 28.140 -7.739 0.431 1.00 50.61 ? 35 LEU B CG 1 ATOM 841 C CD1 . LEU B 2 36 ? 29.393 -8.573 0.645 1.00 51.30 ? 35 LEU B CD1 1 ATOM 842 C CD2 . LEU B 2 36 ? 27.493 -8.066 -0.903 1.00 51.74 ? 35 LEU B CD2 1 ATOM 843 N N . GLN B 2 37 ? 29.213 -5.784 3.233 1.00 45.94 ? 36 GLN B N 1 ATOM 844 C CA . GLN B 2 37 ? 29.715 -4.410 3.160 1.00 45.72 ? 36 GLN B CA 1 ATOM 845 C C . GLN B 2 37 ? 30.526 -4.225 1.890 1.00 44.60 ? 36 GLN B C 1 ATOM 846 O O . GLN B 2 37 ? 31.551 -4.877 1.701 1.00 44.31 ? 36 GLN B O 1 ATOM 847 C CB . GLN B 2 37 ? 30.598 -4.085 4.356 1.00 46.08 ? 36 GLN B CB 1 ATOM 848 C CG . GLN B 2 37 ? 30.007 -4.520 5.672 1.00 47.66 ? 36 GLN B CG 1 ATOM 849 C CD . GLN B 2 37 ? 30.714 -3.910 6.854 1.00 49.39 ? 36 GLN B CD 1 ATOM 850 O OE1 . GLN B 2 37 ? 31.871 -3.493 6.764 1.00 51.13 ? 36 GLN B OE1 1 ATOM 851 N NE2 . GLN B 2 37 ? 30.021 -3.861 7.982 1.00 51.92 ? 36 GLN B NE2 1 ATOM 852 N N . LEU B 2 38 ? 30.064 -3.338 1.022 1.00 44.13 ? 37 LEU B N 1 ATOM 853 C CA . LEU B 2 38 ? 30.777 -3.024 -0.206 1.00 44.83 ? 37 LEU B CA 1 ATOM 854 C C . LEU B 2 38 ? 31.746 -1.874 0.085 1.00 42.31 ? 37 LEU B C 1 ATOM 855 O O . LEU B 2 38 ? 31.352 -0.875 0.688 1.00 42.01 ? 37 LEU B O 1 ATOM 856 C CB . LEU B 2 38 ? 29.774 -2.647 -1.294 1.00 46.57 ? 37 LEU B CB 1 ATOM 857 C CG . LEU B 2 38 ? 30.336 -2.461 -2.695 1.00 50.14 ? 37 LEU B CG 1 ATOM 858 C CD1 . LEU B 2 38 ? 31.022 -3.734 -3.178 1.00 53.06 ? 37 LEU B CD1 1 ATOM 859 C CD2 . LEU B 2 38 ? 29.213 -2.056 -3.636 1.00 51.82 ? 37 LEU B CD2 1 ATOM 860 N N . ILE B 2 39 ? 33.005 -2.026 -0.328 1.00 39.12 ? 38 ILE B N 1 ATOM 861 C CA . ILE B 2 39 ? 34.076 -1.060 -0.005 1.00 37.48 ? 38 ILE B CA 1 ATOM 862 C C . ILE B 2 39 ? 34.487 -0.237 -1.221 1.00 36.66 ? 38 ILE B C 1 ATOM 863 O O . ILE B 2 39 ? 34.508 0.989 -1.160 1.00 35.84 ? 38 ILE B O 1 ATOM 864 C CB . ILE B 2 39 ? 35.330 -1.770 0.582 1.00 36.69 ? 38 ILE B CB 1 ATOM 865 C CG1 . ILE B 2 39 ? 34.959 -2.585 1.830 1.00 36.51 ? 38 ILE B CG1 1 ATOM 866 C CG2 . ILE B 2 39 ? 36.441 -0.780 0.905 1.00 35.71 ? 38 ILE B CG2 1 ATOM 867 C CD1 . ILE B 2 39 ? 34.290 -1.788 2.926 1.00 36.76 ? 38 ILE B CD1 1 ATOM 868 N N . GLN B 2 40 ? 34.839 -0.913 -2.311 1.00 37.24 ? 39 GLN B N 1 ATOM 869 C CA . GLN B 2 40 ? 35.277 -0.237 -3.529 1.00 38.49 ? 39 GLN B CA 1 ATOM 870 C C . GLN B 2 40 ? 35.261 -1.164 -4.744 1.00 38.73 ? 39 GLN B C 1 ATOM 871 O O . GLN B 2 40 ? 35.684 -2.317 -4.633 1.00 37.68 ? 39 GLN B O 1 ATOM 872 C CB . GLN B 2 40 ? 36.698 0.303 -3.329 1.00 39.07 ? 39 GLN B CB 1 ATOM 873 C CG . GLN B 2 40 ? 37.064 1.442 -4.257 1.00 39.43 ? 39 GLN B CG 1 ATOM 874 C CD . GLN B 2 40 ? 38.359 2.114 -3.858 1.00 41.03 ? 39 GLN B CD 1 ATOM 875 O OE1 . GLN B 2 40 ? 39.204 1.514 -3.193 1.00 43.58 ? 39 GLN B OE1 1 ATOM 876 N NE2 . GLN B 2 40 ? 38.523 3.368 -4.261 1.00 40.98 ? 39 GLN B NE2 1 ATOM 877 N N . LEU B 2 41 ? 34.779 -0.659 -5.888 1.00 39.15 ? 40 LEU B N 1 ATOM 878 C CA . LEU B 2 41 ? 35.015 -1.311 -7.180 1.00 39.71 ? 40 LEU B CA 1 ATOM 879 C C . LEU B 2 41 ? 36.478 -1.087 -7.508 1.00 38.52 ? 40 LEU B C 1 ATOM 880 O O . LEU B 2 41 ? 36.914 0.061 -7.571 1.00 38.29 ? 40 LEU B O 1 ATOM 881 C CB . LEU B 2 41 ? 34.181 -0.704 -8.315 1.00 41.45 ? 40 LEU B CB 1 ATOM 882 C CG . LEU B 2 41 ? 32.675 -0.500 -8.176 1.00 43.09 ? 40 LEU B CG 1 ATOM 883 C CD1 . LEU B 2 41 ? 32.107 -0.175 -9.544 1.00 44.26 ? 40 LEU B CD1 1 ATOM 884 C CD2 . LEU B 2 41 ? 31.970 -1.706 -7.604 1.00 43.50 ? 40 LEU B CD2 1 ATOM 885 N N . ILE B 2 42 ? 37.226 -2.170 -7.708 1.00 37.33 ? 41 ILE B N 1 ATOM 886 C CA . ILE B 2 42 ? 38.674 -2.085 -7.977 1.00 37.25 ? 41 ILE B CA 1 ATOM 887 C C . ILE B 2 42 ? 39.055 -2.454 -9.414 1.00 38.12 ? 41 ILE B C 1 ATOM 888 O O . ILE B 2 42 ? 40.205 -2.271 -9.802 1.00 39.54 ? 41 ILE B O 1 ATOM 889 C CB . ILE B 2 42 ? 39.521 -2.914 -6.963 1.00 35.85 ? 41 ILE B CB 1 ATOM 890 C CG1 . ILE B 2 42 ? 39.260 -4.420 -7.080 1.00 36.13 ? 41 ILE B CG1 1 ATOM 891 C CG2 . ILE B 2 42 ? 39.227 -2.478 -5.537 1.00 36.05 ? 41 ILE B CG2 1 ATOM 892 C CD1 . ILE B 2 42 ? 40.051 -5.263 -6.104 1.00 36.14 ? 41 ILE B CD1 1 ATOM 893 N N . ASN B 2 43 ? 38.110 -2.978 -10.194 1.00 38.72 ? 42 ASN B N 1 ATOM 894 C CA . ASN B 2 43 ? 38.365 -3.325 -11.593 1.00 39.70 ? 42 ASN B CA 1 ATOM 895 C C . ASN B 2 43 ? 37.040 -3.459 -12.349 1.00 39.80 ? 42 ASN B C 1 ATOM 896 O O . ASN B 2 43 ? 36.058 -3.924 -11.783 1.00 39.90 ? 42 ASN B O 1 ATOM 897 C CB . ASN B 2 43 ? 39.158 -4.631 -11.674 1.00 40.62 ? 42 ASN B CB 1 ATOM 898 C CG . ASN B 2 43 ? 39.583 -4.974 -13.087 1.00 42.38 ? 42 ASN B CG 1 ATOM 899 O OD1 . ASN B 2 43 ? 38.922 -5.759 -13.767 1.00 45.84 ? 42 ASN B OD1 1 ATOM 900 N ND2 . ASN B 2 43 ? 40.684 -4.383 -13.540 1.00 42.78 ? 42 ASN B ND2 1 ATOM 901 N N . VAL B 2 44 ? 37.007 -3.024 -13.608 1.00 40.35 ? 43 VAL B N 1 ATOM 902 C CA . VAL B 2 44 ? 35.819 -3.175 -14.459 1.00 41.15 ? 43 VAL B CA 1 ATOM 903 C C . VAL B 2 44 ? 36.225 -3.631 -15.866 1.00 42.86 ? 43 VAL B C 1 ATOM 904 O O . VAL B 2 44 ? 36.775 -2.858 -16.651 1.00 42.98 ? 43 VAL B O 1 ATOM 905 C CB . VAL B 2 44 ? 34.997 -1.866 -14.548 1.00 41.23 ? 43 VAL B CB 1 ATOM 906 C CG1 . VAL B 2 44 ? 33.793 -2.039 -15.469 1.00 41.15 ? 43 VAL B CG1 1 ATOM 907 C CG2 . VAL B 2 44 ? 34.544 -1.415 -13.166 1.00 41.25 ? 43 VAL B CG2 1 ATOM 908 N N . ASP B 2 45 ? 35.940 -4.897 -16.161 1.00 46.06 ? 44 ASP B N 1 ATOM 909 C CA . ASP B 2 45 ? 36.138 -5.501 -17.480 1.00 47.44 ? 44 ASP B CA 1 ATOM 910 C C . ASP B 2 45 ? 34.833 -5.395 -18.278 1.00 47.21 ? 44 ASP B C 1 ATOM 911 O O . ASP B 2 45 ? 33.872 -6.102 -17.985 1.00 48.59 ? 44 ASP B O 1 ATOM 912 C CB . ASP B 2 45 ? 36.531 -6.972 -17.279 1.00 48.81 ? 44 ASP B CB 1 ATOM 913 C CG . ASP B 2 45 ? 36.942 -7.669 -18.560 1.00 51.10 ? 44 ASP B CG 1 ATOM 914 O OD1 . ASP B 2 45 ? 36.423 -7.331 -19.651 1.00 53.26 ? 44 ASP B OD1 1 ATOM 915 O OD2 . ASP B 2 45 ? 37.784 -8.587 -18.462 1.00 51.04 ? 44 ASP B OD2 1 ATOM 916 N N . GLU B 2 46 ? 34.797 -4.512 -19.275 1.00 47.96 ? 45 GLU B N 1 ATOM 917 C CA . GLU B 2 46 ? 33.575 -4.281 -20.073 1.00 49.99 ? 45 GLU B CA 1 ATOM 918 C C . GLU B 2 46 ? 33.424 -5.259 -21.242 1.00 52.30 ? 45 GLU B C 1 ATOM 919 O O . GLU B 2 46 ? 32.323 -5.417 -21.781 1.00 52.83 ? 45 GLU B O 1 ATOM 920 C CB . GLU B 2 46 ? 33.526 -2.842 -20.581 1.00 50.12 ? 45 GLU B CB 1 ATOM 921 C CG . GLU B 2 46 ? 33.714 -1.814 -19.474 1.00 52.95 ? 45 GLU B CG 1 ATOM 922 C CD . GLU B 2 46 ? 33.000 -0.503 -19.734 1.00 55.67 ? 45 GLU B CD 1 ATOM 923 O OE1 . GLU B 2 46 ? 31.756 -0.474 -19.623 1.00 57.24 ? 45 GLU B OE1 1 ATOM 924 O OE2 . GLU B 2 46 ? 33.680 0.505 -20.027 1.00 58.65 ? 45 GLU B OE2 1 ATOM 925 N N . VAL B 2 47 ? 34.527 -5.913 -21.618 1.00 52.85 ? 46 VAL B N 1 ATOM 926 C CA . VAL B 2 47 ? 34.533 -6.942 -22.666 1.00 53.05 ? 46 VAL B CA 1 ATOM 927 C C . VAL B 2 47 ? 33.778 -8.188 -22.192 1.00 51.65 ? 46 VAL B C 1 ATOM 928 O O . VAL B 2 47 ? 32.914 -8.701 -22.906 1.00 51.22 ? 46 VAL B O 1 ATOM 929 C CB . VAL B 2 47 ? 35.990 -7.317 -23.080 1.00 53.94 ? 46 VAL B CB 1 ATOM 930 C CG1 . VAL B 2 47 ? 36.031 -8.545 -23.989 1.00 54.01 ? 46 VAL B CG1 1 ATOM 931 C CG2 . VAL B 2 47 ? 36.673 -6.136 -23.758 1.00 53.49 ? 46 VAL B CG2 1 ATOM 932 N N . ASN B 2 48 ? 34.127 -8.654 -20.993 1.00 50.60 ? 47 ASN B N 1 ATOM 933 C CA . ASN B 2 48 ? 33.519 -9.834 -20.365 1.00 50.79 ? 47 ASN B CA 1 ATOM 934 C C . ASN B 2 48 ? 32.454 -9.501 -19.317 1.00 49.27 ? 47 ASN B C 1 ATOM 935 O O . ASN B 2 48 ? 31.869 -10.414 -18.738 1.00 50.26 ? 47 ASN B O 1 ATOM 936 C CB . ASN B 2 48 ? 34.605 -10.672 -19.697 1.00 52.98 ? 47 ASN B CB 1 ATOM 937 C CG . ASN B 2 48 ? 35.748 -10.985 -20.633 1.00 56.38 ? 47 ASN B CG 1 ATOM 938 O OD1 . ASN B 2 48 ? 36.894 -10.618 -20.377 1.00 57.64 ? 47 ASN B OD1 1 ATOM 939 N ND2 . ASN B 2 48 ? 35.436 -11.644 -21.745 1.00 59.38 ? 47 ASN B ND2 1 ATOM 940 N N . GLN B 2 49 ? 32.222 -8.210 -19.065 1.00 47.96 ? 48 GLN B N 1 ATOM 941 C CA . GLN B 2 49 ? 31.216 -7.737 -18.112 1.00 47.53 ? 48 GLN B CA 1 ATOM 942 C C . GLN B 2 49 ? 31.457 -8.284 -16.699 1.00 44.30 ? 48 GLN B C 1 ATOM 943 O O . GLN B 2 49 ? 30.541 -8.773 -16.038 1.00 43.26 ? 48 GLN B O 1 ATOM 944 C CB . GLN B 2 49 ? 29.795 -8.041 -18.619 1.00 50.55 ? 48 GLN B CB 1 ATOM 945 C CG . GLN B 2 49 ? 29.482 -7.398 -19.966 1.00 53.70 ? 48 GLN B CG 1 ATOM 946 C CD . GLN B 2 49 ? 28.219 -7.931 -20.631 1.00 55.74 ? 48 GLN B CD 1 ATOM 947 O OE1 . GLN B 2 49 ? 28.113 -7.924 -21.856 1.00 59.03 ? 48 GLN B OE1 1 ATOM 948 N NE2 . GLN B 2 49 ? 27.258 -8.385 -19.833 1.00 56.32 ? 48 GLN B NE2 1 ATOM 949 N N . ILE B 2 50 ? 32.704 -8.177 -16.248 1.00 42.67 ? 49 ILE B N 1 ATOM 950 C CA . ILE B 2 50 ? 33.109 -8.627 -14.916 1.00 42.20 ? 49 ILE B CA 1 ATOM 951 C C . ILE B 2 50 ? 33.614 -7.439 -14.100 1.00 39.90 ? 49 ILE B C 1 ATOM 952 O O . ILE B 2 50 ? 34.461 -6.687 -14.573 1.00 37.22 ? 49 ILE B O 1 ATOM 953 C CB . ILE B 2 50 ? 34.216 -9.699 -15.014 1.00 43.60 ? 49 ILE B CB 1 ATOM 954 C CG1 . ILE B 2 50 ? 33.653 -10.986 -15.628 1.00 45.41 ? 49 ILE B CG1 1 ATOM 955 C CG2 . ILE B 2 50 ? 34.832 -10.004 -13.649 1.00 44.55 ? 49 ILE B CG2 1 ATOM 956 C CD1 . ILE B 2 50 ? 34.701 -11.846 -16.303 1.00 46.44 ? 49 ILE B CD1 1 ATOM 957 N N . VAL B 2 51 ? 33.104 -7.301 -12.873 1.00 39.32 ? 50 VAL B N 1 ATOM 958 C CA . VAL B 2 51 ? 33.591 -6.293 -11.915 1.00 39.44 ? 50 VAL B CA 1 ATOM 959 C C . VAL B 2 51 ? 34.199 -6.953 -10.672 1.00 37.72 ? 50 VAL B C 1 ATOM 960 O O . VAL B 2 51 ? 33.576 -7.805 -10.051 1.00 36.46 ? 50 VAL B O 1 ATOM 961 C CB . VAL B 2 51 ? 32.504 -5.259 -11.517 1.00 40.00 ? 50 VAL B CB 1 ATOM 962 C CG1 . VAL B 2 51 ? 31.959 -4.577 -12.757 1.00 40.88 ? 50 VAL B CG1 1 ATOM 963 C CG2 . VAL B 2 51 ? 31.360 -5.883 -10.729 1.00 41.60 ? 50 VAL B CG2 1 ATOM 964 N N . THR B 2 52 ? 35.433 -6.578 -10.345 1.00 37.86 ? 51 THR B N 1 ATOM 965 C CA . THR B 2 52 ? 36.077 -7.019 -9.119 1.00 38.48 ? 51 THR B CA 1 ATOM 966 C C . THR B 2 52 ? 35.746 -5.991 -8.053 1.00 40.24 ? 51 THR B C 1 ATOM 967 O O . THR B 2 52 ? 36.015 -4.798 -8.244 1.00 41.46 ? 51 THR B O 1 ATOM 968 C CB . THR B 2 52 ? 37.608 -7.114 -9.260 1.00 38.12 ? 51 THR B CB 1 ATOM 969 O OG1 . THR B 2 52 ? 37.952 -7.938 -10.380 1.00 37.85 ? 51 THR B OG1 1 ATOM 970 C CG2 . THR B 2 52 ? 38.224 -7.715 -8.014 1.00 38.05 ? 51 THR B CG2 1 ATOM 971 N N . THR B 2 53 ? 35.159 -6.444 -6.945 1.00 40.50 ? 52 THR B N 1 ATOM 972 C CA . THR B 2 53 ? 34.879 -5.567 -5.814 1.00 42.83 ? 52 THR B CA 1 ATOM 973 C C . THR B 2 53 ? 35.629 -6.019 -4.581 1.00 42.49 ? 52 THR B C 1 ATOM 974 O O . THR B 2 53 ? 35.890 -7.203 -4.401 1.00 43.35 ? 52 THR B O 1 ATOM 975 C CB . THR B 2 53 ? 33.384 -5.511 -5.470 1.00 44.34 ? 52 THR B CB 1 ATOM 976 O OG1 . THR B 2 53 ? 32.933 -6.807 -5.060 1.00 48.26 ? 52 THR B OG1 1 ATOM 977 C CG2 . THR B 2 53 ? 32.590 -5.045 -6.665 1.00 44.26 ? 52 THR B CG2 1 ATOM 978 N N . ASN B 2 54 ? 35.970 -5.050 -3.742 1.00 43.21 ? 53 ASN B N 1 ATOM 979 C CA . ASN B 2 54 ? 36.505 -5.298 -2.421 1.00 43.82 ? 53 ASN B CA 1 ATOM 980 C C . ASN B 2 54 ? 35.322 -5.244 -1.447 1.00 42.11 ? 53 ASN B C 1 ATOM 981 O O . ASN B 2 54 ? 34.585 -4.262 -1.417 1.00 39.89 ? 53 ASN B O 1 ATOM 982 C CB . ASN B 2 54 ? 37.535 -4.227 -2.101 1.00 45.86 ? 53 ASN B CB 1 ATOM 983 C CG . ASN B 2 54 ? 38.285 -4.493 -0.821 1.00 49.48 ? 53 ASN B CG 1 ATOM 984 O OD1 . ASN B 2 54 ? 37.800 -5.169 0.092 1.00 52.64 ? 53 ASN B OD1 1 ATOM 985 N ND2 . ASN B 2 54 ? 39.478 -3.931 -0.734 1.00 53.36 ? 53 ASN B ND2 1 ATOM 986 N N . VAL B 2 55 ? 35.137 -6.310 -0.669 1.00 41.67 ? 54 VAL B N 1 ATOM 987 C CA . VAL B 2 55 ? 34.032 -6.397 0.294 1.00 41.72 ? 54 VAL B CA 1 ATOM 988 C C . VAL B 2 55 ? 34.510 -6.788 1.685 1.00 42.35 ? 54 VAL B C 1 ATOM 989 O O . VAL B 2 55 ? 35.683 -7.109 1.883 1.00 44.10 ? 54 VAL B O 1 ATOM 990 C CB . VAL B 2 55 ? 32.945 -7.400 -0.147 1.00 40.04 ? 54 VAL B CB 1 ATOM 991 C CG1 . VAL B 2 55 ? 32.342 -6.974 -1.472 1.00 40.39 ? 54 VAL B CG1 1 ATOM 992 C CG2 . VAL B 2 55 ? 33.495 -8.818 -0.229 1.00 40.33 ? 54 VAL B CG2 1 ATOM 993 N N . ARG B 2 56 ? 33.595 -6.701 2.646 1.00 41.44 ? 55 ARG B N 1 ATOM 994 C CA . ARG B 2 56 ? 33.717 -7.409 3.910 1.00 42.78 ? 55 ARG B CA 1 ATOM 995 C C . ARG B 2 56 ? 32.414 -8.148 4.131 1.00 42.49 ? 55 ARG B C 1 ATOM 996 O O . ARG B 2 56 ? 31.331 -7.631 3.846 1.00 41.68 ? 55 ARG B O 1 ATOM 997 C CB . ARG B 2 56 ? 34.028 -6.468 5.066 1.00 45.10 ? 55 ARG B CB 1 ATOM 998 C CG . ARG B 2 56 ? 35.439 -5.914 5.011 1.00 48.36 ? 55 ARG B CG 1 ATOM 999 C CD . ARG B 2 56 ? 35.627 -4.682 5.882 1.00 53.19 ? 55 ARG B CD 1 ATOM 1000 N NE . ARG B 2 56 ? 36.636 -3.779 5.313 1.00 57.66 ? 55 ARG B NE 1 ATOM 1001 C CZ . ARG B 2 56 ? 36.745 -2.468 5.568 1.00 60.53 ? 55 ARG B CZ 1 ATOM 1002 N NH1 . ARG B 2 56 ? 35.912 -1.833 6.405 1.00 59.71 ? 55 ARG B NH1 1 ATOM 1003 N NH2 . ARG B 2 56 ? 37.706 -1.771 4.962 1.00 61.68 ? 55 ARG B NH2 1 ATOM 1004 N N . LEU B 2 57 ? 32.534 -9.372 4.626 1.00 43.88 ? 56 LEU B N 1 ATOM 1005 C CA . LEU B 2 57 ? 31.414 -10.283 4.741 1.00 44.31 ? 56 LEU B CA 1 ATOM 1006 C C . LEU B 2 57 ? 31.043 -10.396 6.210 1.00 43.06 ? 56 LEU B C 1 ATOM 1007 O O . LEU B 2 57 ? 31.419 -11.353 6.870 1.00 44.34 ? 56 LEU B O 1 ATOM 1008 C CB . LEU B 2 57 ? 31.823 -11.630 4.141 1.00 46.20 ? 56 LEU B CB 1 ATOM 1009 C CG . LEU B 2 57 ? 30.831 -12.789 4.171 1.00 48.65 ? 56 LEU B CG 1 ATOM 1010 C CD1 . LEU B 2 57 ? 29.483 -12.345 3.646 1.00 50.46 ? 56 LEU B CD1 1 ATOM 1011 C CD2 . LEU B 2 57 ? 31.359 -13.974 3.369 1.00 49.32 ? 56 LEU B CD2 1 ATOM 1012 N N . LYS B 2 58 ? 30.308 -9.408 6.717 1.00 42.47 ? 57 LYS B N 1 ATOM 1013 C CA . LYS B 2 58 ? 30.070 -9.286 8.160 1.00 43.83 ? 57 LYS B CA 1 ATOM 1014 C C . LYS B 2 58 ? 29.130 -10.359 8.705 1.00 42.28 ? 57 LYS B C 1 ATOM 1015 O O . LYS B 2 58 ? 28.011 -10.509 8.217 1.00 42.73 ? 57 LYS B O 1 ATOM 1016 C CB . LYS B 2 58 ? 29.520 -7.902 8.518 1.00 46.97 ? 57 LYS B CB 1 ATOM 1017 C CG . LYS B 2 58 ? 29.676 -7.547 9.999 1.00 49.37 ? 57 LYS B CG 1 ATOM 1018 C CD . LYS B 2 58 ? 28.809 -6.357 10.389 1.00 52.43 ? 57 LYS B CD 1 ATOM 1019 C CE . LYS B 2 58 ? 28.665 -6.204 11.897 1.00 53.48 ? 57 LYS B CE 1 ATOM 1020 N NZ . LYS B 2 58 ? 27.538 -5.292 12.255 1.00 53.71 ? 57 LYS B NZ 1 ATOM 1021 N N . GLN B 2 59 ? 29.593 -11.081 9.728 1.00 40.23 ? 58 GLN B N 1 ATOM 1022 C CA . GLN B 2 59 ? 28.852 -12.197 10.323 1.00 39.59 ? 58 GLN B CA 1 ATOM 1023 C C . GLN B 2 59 ? 28.725 -12.040 11.844 1.00 39.80 ? 58 GLN B C 1 ATOM 1024 O O . GLN B 2 59 ? 29.650 -11.562 12.506 1.00 40.69 ? 58 GLN B O 1 ATOM 1025 C CB . GLN B 2 59 ? 29.552 -13.517 9.995 1.00 38.16 ? 58 GLN B CB 1 ATOM 1026 C CG . GLN B 2 59 ? 29.583 -13.862 8.515 1.00 36.70 ? 58 GLN B CG 1 ATOM 1027 C CD . GLN B 2 59 ? 30.755 -14.743 8.152 1.00 35.57 ? 58 GLN B CD 1 ATOM 1028 O OE1 . GLN B 2 59 ? 30.876 -15.858 8.643 1.00 37.60 ? 58 GLN B OE1 1 ATOM 1029 N NE2 . GLN B 2 59 ? 31.624 -14.248 7.296 1.00 34.47 ? 58 GLN B NE2 1 ATOM 1030 N N . GLN B 2 60 ? 27.575 -12.440 12.387 1.00 39.58 ? 59 GLN B N 1 ATOM 1031 C CA . GLN B 2 60 ? 27.331 -12.400 13.823 1.00 39.65 ? 59 GLN B CA 1 ATOM 1032 C C . GLN B 2 60 ? 26.524 -13.608 14.275 1.00 38.91 ? 59 GLN B C 1 ATOM 1033 O O . GLN B 2 60 ? 25.464 -13.880 13.711 1.00 37.16 ? 59 GLN B O 1 ATOM 1034 C CB . GLN B 2 60 ? 26.548 -11.151 14.209 1.00 41.54 ? 59 GLN B CB 1 ATOM 1035 C CG . GLN B 2 60 ? 27.240 -9.828 13.954 1.00 43.93 ? 59 GLN B CG 1 ATOM 1036 C CD . GLN B 2 60 ? 26.350 -8.656 14.325 1.00 45.34 ? 59 GLN B CD 1 ATOM 1037 O OE1 . GLN B 2 60 ? 25.912 -8.536 15.468 1.00 47.84 ? 59 GLN B OE1 1 ATOM 1038 N NE2 . GLN B 2 60 ? 26.070 -7.790 13.358 1.00 47.50 ? 59 GLN B NE2 1 ATOM 1039 N N . TRP B 2 61 ? 27.020 -14.302 15.302 1.00 38.47 ? 60 TRP B N 1 ATOM 1040 C CA . TRP B 2 61 ? 26.282 -15.377 15.975 1.00 38.34 ? 60 TRP B CA 1 ATOM 1041 C C . TRP B 2 61 ? 26.717 -15.487 17.433 1.00 37.45 ? 60 TRP B C 1 ATOM 1042 O O . TRP B 2 61 ? 27.674 -14.832 17.838 1.00 37.38 ? 60 TRP B O 1 ATOM 1043 C CB . TRP B 2 61 ? 26.500 -16.709 15.247 1.00 38.76 ? 60 TRP B CB 1 ATOM 1044 C CG . TRP B 2 61 ? 27.921 -17.250 15.308 1.00 38.03 ? 60 TRP B CG 1 ATOM 1045 C CD1 . TRP B 2 61 ? 28.413 -18.181 16.191 1.00 37.59 ? 60 TRP B CD1 1 ATOM 1046 C CD2 . TRP B 2 61 ? 29.009 -16.903 14.449 1.00 36.63 ? 60 TRP B CD2 1 ATOM 1047 N NE1 . TRP B 2 61 ? 29.739 -18.429 15.932 1.00 36.80 ? 60 TRP B NE1 1 ATOM 1048 C CE2 . TRP B 2 61 ? 30.132 -17.660 14.867 1.00 37.02 ? 60 TRP B CE2 1 ATOM 1049 C CE3 . TRP B 2 61 ? 29.149 -16.027 13.368 1.00 36.92 ? 60 TRP B CE3 1 ATOM 1050 C CZ2 . TRP B 2 61 ? 31.379 -17.564 14.239 1.00 36.47 ? 60 TRP B CZ2 1 ATOM 1051 C CZ3 . TRP B 2 61 ? 30.391 -15.933 12.738 1.00 37.07 ? 60 TRP B CZ3 1 ATOM 1052 C CH2 . TRP B 2 61 ? 31.489 -16.697 13.181 1.00 37.21 ? 60 TRP B CH2 1 ATOM 1053 N N . VAL B 2 62 ? 26.022 -16.325 18.201 1.00 37.94 ? 61 VAL B N 1 ATOM 1054 C CA . VAL B 2 62 ? 26.330 -16.556 19.626 1.00 39.76 ? 61 VAL B CA 1 ATOM 1055 C C . VAL B 2 62 ? 26.839 -17.985 19.859 1.00 40.12 ? 61 VAL B C 1 ATOM 1056 O O . VAL B 2 62 ? 26.166 -18.940 19.487 1.00 41.62 ? 61 VAL B O 1 ATOM 1057 C CB . VAL B 2 62 ? 25.081 -16.307 20.508 1.00 39.87 ? 61 VAL B CB 1 ATOM 1058 C CG1 . VAL B 2 62 ? 25.322 -16.737 21.953 1.00 40.42 ? 61 VAL B CG1 1 ATOM 1059 C CG2 . VAL B 2 62 ? 24.691 -14.836 20.457 1.00 40.29 ? 61 VAL B CG2 1 ATOM 1060 N N . ASP B 2 63 ? 28.014 -18.121 20.474 1.00 40.18 ? 62 ASP B N 1 ATOM 1061 C CA . ASP B 2 63 ? 28.561 -19.426 20.847 1.00 42.19 ? 62 ASP B CA 1 ATOM 1062 C C . ASP B 2 63 ? 28.393 -19.573 22.346 1.00 42.77 ? 62 ASP B C 1 ATOM 1063 O O . ASP B 2 63 ? 29.083 -18.894 23.101 1.00 45.32 ? 62 ASP B O 1 ATOM 1064 C CB . ASP B 2 63 ? 30.045 -19.537 20.459 1.00 42.81 ? 62 ASP B CB 1 ATOM 1065 C CG . ASP B 2 63 ? 30.599 -20.967 20.604 1.00 44.76 ? 62 ASP B CG 1 ATOM 1066 O OD1 . ASP B 2 63 ? 30.181 -21.709 21.528 1.00 44.87 ? 62 ASP B OD1 1 ATOM 1067 O OD2 . ASP B 2 63 ? 31.460 -21.355 19.779 1.00 45.02 ? 62 ASP B OD2 1 ATOM 1068 N N . TYR B 2 64 ? 27.499 -20.465 22.776 1.00 43.50 ? 63 TYR B N 1 ATOM 1069 C CA . TYR B 2 64 ? 27.151 -20.582 24.209 1.00 45.04 ? 63 TYR B CA 1 ATOM 1070 C C . TYR B 2 64 ? 28.300 -21.083 25.097 1.00 42.46 ? 63 TYR B C 1 ATOM 1071 O O . TYR B 2 64 ? 28.371 -20.741 26.280 1.00 41.09 ? 63 TYR B O 1 ATOM 1072 C CB . TYR B 2 64 ? 25.877 -21.425 24.417 1.00 48.07 ? 63 TYR B CB 1 ATOM 1073 C CG . TYR B 2 64 ? 26.076 -22.922 24.442 1.00 51.90 ? 63 TYR B CG 1 ATOM 1074 C CD1 . TYR B 2 64 ? 26.198 -23.648 23.256 1.00 56.18 ? 63 TYR B CD1 1 ATOM 1075 C CD2 . TYR B 2 64 ? 26.123 -23.621 25.650 1.00 53.75 ? 63 TYR B CD2 1 ATOM 1076 C CE1 . TYR B 2 64 ? 26.371 -25.029 23.269 1.00 59.20 ? 63 TYR B CE1 1 ATOM 1077 C CE2 . TYR B 2 64 ? 26.300 -24.998 25.677 1.00 56.36 ? 63 TYR B CE2 1 ATOM 1078 C CZ . TYR B 2 64 ? 26.420 -25.702 24.485 1.00 59.25 ? 63 TYR B CZ 1 ATOM 1079 O OH . TYR B 2 64 ? 26.597 -27.070 24.496 1.00 61.05 ? 63 TYR B OH 1 ATOM 1080 N N . ASN B 2 65 ? 29.208 -21.860 24.512 1.00 40.87 ? 64 ASN B N 1 ATOM 1081 C CA . ASN B 2 65 ? 30.376 -22.370 25.230 1.00 39.46 ? 64 ASN B CA 1 ATOM 1082 C C . ASN B 2 65 ? 31.483 -21.349 25.449 1.00 37.47 ? 64 ASN B C 1 ATOM 1083 O O . ASN B 2 65 ? 32.442 -21.650 26.157 1.00 36.92 ? 64 ASN B O 1 ATOM 1084 C CB . ASN B 2 65 ? 30.944 -23.606 24.521 1.00 40.62 ? 64 ASN B CB 1 ATOM 1085 C CG . ASN B 2 65 ? 30.068 -24.833 24.707 1.00 41.34 ? 64 ASN B CG 1 ATOM 1086 O OD1 . ASN B 2 65 ? 29.807 -25.256 25.836 1.00 42.99 ? 64 ASN B OD1 1 ATOM 1087 N ND2 . ASN B 2 65 ? 29.602 -25.403 23.604 1.00 40.59 ? 64 ASN B ND2 1 ATOM 1088 N N . LEU B 2 66 ? 31.357 -20.157 24.866 1.00 37.53 ? 65 LEU B N 1 ATOM 1089 C CA . LEU B 2 66 ? 32.370 -19.099 25.009 1.00 37.91 ? 65 LEU B CA 1 ATOM 1090 C C . LEU B 2 66 ? 31.913 -17.911 25.866 1.00 37.73 ? 65 LEU B C 1 ATOM 1091 O O . LEU B 2 66 ? 32.419 -16.803 25.704 1.00 37.32 ? 65 LEU B O 1 ATOM 1092 C CB . LEU B 2 66 ? 32.824 -18.628 23.619 1.00 37.21 ? 65 LEU B CB 1 ATOM 1093 C CG . LEU B 2 66 ? 33.437 -19.731 22.746 1.00 36.78 ? 65 LEU B CG 1 ATOM 1094 C CD1 . LEU B 2 66 ? 33.689 -19.237 21.332 1.00 36.83 ? 65 LEU B CD1 1 ATOM 1095 C CD2 . LEU B 2 66 ? 34.719 -20.265 23.374 1.00 36.70 ? 65 LEU B CD2 1 ATOM 1096 N N . LYS B 2 67 ? 30.981 -18.151 26.790 1.00 38.08 ? 66 LYS B N 1 ATOM 1097 C CA . LYS B 2 67 ? 30.593 -17.149 27.779 1.00 38.37 ? 66 LYS B CA 1 ATOM 1098 C C . LYS B 2 67 ? 31.635 -17.140 28.890 1.00 37.98 ? 66 LYS B C 1 ATOM 1099 O O . LYS B 2 67 ? 32.282 -18.158 29.146 1.00 37.06 ? 66 LYS B O 1 ATOM 1100 C CB . LYS B 2 67 ? 29.213 -17.467 28.363 1.00 40.34 ? 66 LYS B CB 1 ATOM 1101 C CG . LYS B 2 67 ? 28.088 -17.450 27.332 1.00 43.28 ? 66 LYS B CG 1 ATOM 1102 C CD . LYS B 2 67 ? 26.892 -18.318 27.718 1.00 44.96 ? 66 LYS B CD 1 ATOM 1103 C CE . LYS B 2 67 ? 26.037 -17.670 28.795 1.00 47.70 ? 66 LYS B CE 1 ATOM 1104 N NZ . LYS B 2 67 ? 25.393 -16.382 28.387 1.00 49.48 ? 66 LYS B NZ 1 ATOM 1105 N N . TRP B 2 68 ? 31.810 -15.986 29.535 1.00 37.89 ? 67 TRP B N 1 ATOM 1106 C CA . TRP B 2 68 ? 32.613 -15.898 30.757 1.00 38.20 ? 67 TRP B CA 1 ATOM 1107 C C . TRP B 2 68 ? 32.074 -14.837 31.719 1.00 38.60 ? 67 TRP B C 1 ATOM 1108 O O . TRP B 2 68 ? 31.217 -14.028 31.352 1.00 37.64 ? 67 TRP B O 1 ATOM 1109 C CB . TRP B 2 68 ? 34.101 -15.658 30.436 1.00 38.95 ? 67 TRP B CB 1 ATOM 1110 C CG . TRP B 2 68 ? 34.443 -14.253 30.011 1.00 39.24 ? 67 TRP B CG 1 ATOM 1111 C CD1 . TRP B 2 68 ? 34.749 -13.201 30.820 1.00 39.31 ? 67 TRP B CD1 1 ATOM 1112 C CD2 . TRP B 2 68 ? 34.531 -13.765 28.670 1.00 40.71 ? 67 TRP B CD2 1 ATOM 1113 N NE1 . TRP B 2 68 ? 35.003 -12.083 30.071 1.00 40.10 ? 67 TRP B NE1 1 ATOM 1114 C CE2 . TRP B 2 68 ? 34.878 -12.402 28.745 1.00 40.33 ? 67 TRP B CE2 1 ATOM 1115 C CE3 . TRP B 2 68 ? 34.348 -14.349 27.409 1.00 40.28 ? 67 TRP B CE3 1 ATOM 1116 C CZ2 . TRP B 2 68 ? 35.037 -11.612 27.611 1.00 40.63 ? 67 TRP B CZ2 1 ATOM 1117 C CZ3 . TRP B 2 68 ? 34.504 -13.568 26.291 1.00 40.03 ? 67 TRP B CZ3 1 ATOM 1118 C CH2 . TRP B 2 68 ? 34.848 -12.210 26.394 1.00 40.66 ? 67 TRP B CH2 1 ATOM 1119 N N . ASN B 2 69 ? 32.595 -14.872 32.947 1.00 39.03 ? 68 ASN B N 1 ATOM 1120 C CA . ASN B 2 69 ? 32.242 -13.948 34.023 1.00 39.56 ? 68 ASN B CA 1 ATOM 1121 C C . ASN B 2 69 ? 33.332 -12.883 34.104 1.00 39.33 ? 68 ASN B C 1 ATOM 1122 O O . ASN B 2 69 ? 34.463 -13.206 34.463 1.00 39.35 ? 68 ASN B O 1 ATOM 1123 C CB . ASN B 2 69 ? 32.145 -14.725 35.354 1.00 41.13 ? 68 ASN B CB 1 ATOM 1124 C CG . ASN B 2 69 ? 31.476 -13.932 36.470 1.00 41.32 ? 68 ASN B CG 1 ATOM 1125 O OD1 . ASN B 2 69 ? 31.379 -12.705 36.419 1.00 42.40 ? 68 ASN B OD1 1 ATOM 1126 N ND2 . ASN B 2 69 ? 31.008 -14.641 37.491 1.00 40.42 ? 68 ASN B ND2 1 ATOM 1127 N N . PRO B 2 70 ? 33.013 -11.615 33.762 1.00 39.63 ? 69 PRO B N 1 ATOM 1128 C CA . PRO B 2 70 ? 34.052 -10.584 33.778 1.00 41.26 ? 69 PRO B CA 1 ATOM 1129 C C . PRO B 2 70 ? 34.804 -10.419 35.099 1.00 42.83 ? 69 PRO B C 1 ATOM 1130 O O . PRO B 2 70 ? 35.986 -10.074 35.073 1.00 44.50 ? 69 PRO B O 1 ATOM 1131 C CB . PRO B 2 70 ? 33.280 -9.306 33.430 1.00 40.10 ? 69 PRO B CB 1 ATOM 1132 C CG . PRO B 2 70 ? 32.180 -9.781 32.565 1.00 38.93 ? 69 PRO B CG 1 ATOM 1133 C CD . PRO B 2 70 ? 31.764 -11.091 33.179 1.00 39.55 ? 69 PRO B CD 1 ATOM 1134 N N . ASP B 2 71 ? 34.149 -10.679 36.229 1.00 44.50 ? 70 ASP B N 1 ATOM 1135 C CA . ASP B 2 71 ? 34.810 -10.576 37.537 1.00 46.67 ? 70 ASP B CA 1 ATOM 1136 C C . ASP B 2 71 ? 35.933 -11.603 37.727 1.00 46.85 ? 70 ASP B C 1 ATOM 1137 O O . ASP B 2 71 ? 36.875 -11.347 38.477 1.00 48.51 ? 70 ASP B O 1 ATOM 1138 C CB . ASP B 2 71 ? 33.789 -10.658 38.685 1.00 49.89 ? 70 ASP B CB 1 ATOM 1139 C CG . ASP B 2 71 ? 32.965 -9.370 38.845 1.00 52.36 ? 70 ASP B CG 1 ATOM 1140 O OD1 . ASP B 2 71 ? 32.719 -8.668 37.842 1.00 54.29 ? 70 ASP B OD1 1 ATOM 1141 O OD2 . ASP B 2 71 ? 32.555 -9.060 39.985 1.00 56.53 ? 70 ASP B OD2 1 ATOM 1142 N N . ASP B 2 72 ? 35.840 -12.745 37.041 1.00 47.79 ? 71 ASP B N 1 ATOM 1143 C CA . ASP B 2 72 ? 36.927 -13.745 37.024 1.00 48.36 ? 71 ASP B CA 1 ATOM 1144 C C . ASP B 2 72 ? 38.187 -13.325 36.264 1.00 45.83 ? 71 ASP B C 1 ATOM 1145 O O . ASP B 2 72 ? 39.243 -13.929 36.461 1.00 44.01 ? 71 ASP B O 1 ATOM 1146 C CB . ASP B 2 72 ? 36.443 -15.081 36.427 1.00 49.88 ? 71 ASP B CB 1 ATOM 1147 C CG . ASP B 2 72 ? 35.464 -15.810 37.323 1.00 51.56 ? 71 ASP B CG 1 ATOM 1148 O OD1 . ASP B 2 72 ? 35.437 -15.513 38.535 1.00 51.77 ? 71 ASP B OD1 1 ATOM 1149 O OD2 . ASP B 2 72 ? 34.737 -16.702 36.823 1.00 51.72 ? 71 ASP B OD2 1 ATOM 1150 N N . TYR B 2 73 ? 38.080 -12.334 35.380 1.00 44.67 ? 72 TYR B N 1 ATOM 1151 C CA . TYR B 2 73 ? 39.194 -11.947 34.506 1.00 45.15 ? 72 TYR B CA 1 ATOM 1152 C C . TYR B 2 73 ? 39.379 -10.430 34.509 1.00 45.25 ? 72 TYR B C 1 ATOM 1153 O O . TYR B 2 73 ? 39.420 -9.787 33.452 1.00 44.84 ? 72 TYR B O 1 ATOM 1154 C CB . TYR B 2 73 ? 38.967 -12.512 33.090 1.00 43.75 ? 72 TYR B CB 1 ATOM 1155 C CG . TYR B 2 73 ? 38.772 -14.018 33.097 1.00 43.92 ? 72 TYR B CG 1 ATOM 1156 C CD1 . TYR B 2 73 ? 39.866 -14.890 33.124 1.00 43.99 ? 72 TYR B CD1 1 ATOM 1157 C CD2 . TYR B 2 73 ? 37.498 -14.574 33.130 1.00 43.75 ? 72 TYR B CD2 1 ATOM 1158 C CE1 . TYR B 2 73 ? 39.690 -16.271 33.157 1.00 42.85 ? 72 TYR B CE1 1 ATOM 1159 C CE2 . TYR B 2 73 ? 37.316 -15.951 33.164 1.00 43.44 ? 72 TYR B CE2 1 ATOM 1160 C CZ . TYR B 2 73 ? 38.411 -16.797 33.179 1.00 42.83 ? 72 TYR B CZ 1 ATOM 1161 O OH . TYR B 2 73 ? 38.212 -18.163 33.221 1.00 42.92 ? 72 TYR B OH 1 ATOM 1162 N N . GLY B 2 74 ? 39.483 -9.881 35.722 1.00 45.02 ? 73 GLY B N 1 ATOM 1163 C CA . GLY B 2 74 ? 39.712 -8.450 35.960 1.00 44.14 ? 73 GLY B CA 1 ATOM 1164 C C . GLY B 2 74 ? 38.772 -7.474 35.272 1.00 43.16 ? 73 GLY B C 1 ATOM 1165 O O . GLY B 2 74 ? 39.171 -6.359 34.945 1.00 43.79 ? 73 GLY B O 1 ATOM 1166 N N . GLY B 2 75 ? 37.528 -7.885 35.053 1.00 43.07 ? 74 GLY B N 1 ATOM 1167 C CA . GLY B 2 75 ? 36.528 -7.037 34.407 1.00 43.79 ? 74 GLY B CA 1 ATOM 1168 C C . GLY B 2 75 ? 36.624 -6.910 32.895 1.00 45.00 ? 74 GLY B C 1 ATOM 1169 O O . GLY B 2 75 ? 36.024 -5.993 32.330 1.00 44.49 ? 74 GLY B O 1 ATOM 1170 N N . VAL B 2 76 ? 37.352 -7.824 32.240 1.00 45.70 ? 75 VAL B N 1 ATOM 1171 C CA . VAL B 2 76 ? 37.444 -7.859 30.771 1.00 46.55 ? 75 VAL B CA 1 ATOM 1172 C C . VAL B 2 76 ? 36.110 -8.318 30.169 1.00 46.60 ? 75 VAL B C 1 ATOM 1173 O O . VAL B 2 76 ? 35.622 -9.402 30.489 1.00 45.75 ? 75 VAL B O 1 ATOM 1174 C CB . VAL B 2 76 ? 38.548 -8.826 30.278 1.00 46.92 ? 75 VAL B CB 1 ATOM 1175 C CG1 . VAL B 2 76 ? 38.498 -8.977 28.760 1.00 47.87 ? 75 VAL B CG1 1 ATOM 1176 C CG2 . VAL B 2 76 ? 39.932 -8.353 30.711 1.00 47.10 ? 75 VAL B CG2 1 ATOM 1177 N N . LYS B 2 77 ? 35.544 -7.490 29.295 1.00 47.04 ? 76 LYS B N 1 ATOM 1178 C CA . LYS B 2 77 ? 34.247 -7.757 28.667 1.00 49.00 ? 76 LYS B CA 1 ATOM 1179 C C . LYS B 2 77 ? 34.335 -8.164 27.189 1.00 47.94 ? 76 LYS B C 1 ATOM 1180 O O . LYS B 2 77 ? 33.321 -8.507 26.579 1.00 46.38 ? 76 LYS B O 1 ATOM 1181 C CB . LYS B 2 77 ? 33.350 -6.530 28.820 1.00 51.32 ? 76 LYS B CB 1 ATOM 1182 C CG . LYS B 2 77 ? 33.078 -6.175 30.271 1.00 55.24 ? 76 LYS B CG 1 ATOM 1183 C CD . LYS B 2 77 ? 32.034 -5.082 30.409 1.00 58.33 ? 76 LYS B CD 1 ATOM 1184 C CE . LYS B 2 77 ? 31.599 -4.944 31.859 1.00 62.99 ? 76 LYS B CE 1 ATOM 1185 N NZ . LYS B 2 77 ? 30.545 -3.905 32.038 1.00 66.31 ? 76 LYS B NZ 1 ATOM 1186 N N . LYS B 2 78 ? 35.534 -8.126 26.615 1.00 47.59 ? 77 LYS B N 1 ATOM 1187 C CA . LYS B 2 78 ? 35.733 -8.557 25.236 1.00 48.49 ? 77 LYS B CA 1 ATOM 1188 C C . LYS B 2 78 ? 37.198 -8.855 24.916 1.00 47.54 ? 77 LYS B C 1 ATOM 1189 O O . LYS B 2 78 ? 38.115 -8.294 25.528 1.00 46.13 ? 77 LYS B O 1 ATOM 1190 C CB . LYS B 2 78 ? 35.138 -7.553 24.230 1.00 48.25 ? 77 LYS B CB 1 ATOM 1191 C CG . LYS B 2 78 ? 35.386 -6.085 24.522 1.00 49.76 ? 77 LYS B CG 1 ATOM 1192 C CD . LYS B 2 78 ? 34.477 -5.203 23.674 1.00 51.19 ? 77 LYS B CD 1 ATOM 1193 N N . ILE B 2 79 ? 37.390 -9.775 23.976 1.00 46.95 ? 78 ILE B N 1 ATOM 1194 C CA . ILE B 2 79 ? 38.711 -10.115 23.459 1.00 47.95 ? 78 ILE B CA 1 ATOM 1195 C C . ILE B 2 79 ? 38.633 -10.361 21.965 1.00 45.61 ? 78 ILE B C 1 ATOM 1196 O O . ILE B 2 79 ? 37.563 -10.651 21.432 1.00 44.64 ? 78 ILE B O 1 ATOM 1197 C CB . ILE B 2 79 ? 39.337 -11.354 24.153 1.00 49.18 ? 78 ILE B CB 1 ATOM 1198 C CG1 . ILE B 2 79 ? 38.316 -12.484 24.304 1.00 50.96 ? 78 ILE B CG1 1 ATOM 1199 C CG2 . ILE B 2 79 ? 39.897 -10.984 25.522 1.00 50.49 ? 78 ILE B CG2 1 ATOM 1200 C CD1 . ILE B 2 79 ? 38.937 -13.787 24.767 1.00 52.13 ? 78 ILE B CD1 1 ATOM 1201 N N . HIS B 2 80 ? 39.780 -10.213 21.306 1.00 45.49 ? 79 HIS B N 1 ATOM 1202 C CA . HIS B 2 80 ? 39.954 -10.605 19.916 1.00 45.17 ? 79 HIS B CA 1 ATOM 1203 C C . HIS B 2 80 ? 40.635 -11.969 19.879 1.00 44.98 ? 79 HIS B C 1 ATOM 1204 O O . HIS B 2 80 ? 41.684 -12.161 20.495 1.00 44.62 ? 79 HIS B O 1 ATOM 1205 C CB . HIS B 2 80 ? 40.789 -9.571 19.165 1.00 45.68 ? 79 HIS B CB 1 ATOM 1206 C CG . HIS B 2 80 ? 40.148 -8.218 19.096 1.00 46.95 ? 79 HIS B CG 1 ATOM 1207 N ND1 . HIS B 2 80 ? 39.172 -7.903 18.173 1.00 47.04 ? 79 HIS B ND1 1 ATOM 1208 C CD2 . HIS B 2 80 ? 40.336 -7.105 19.842 1.00 47.25 ? 79 HIS B CD2 1 ATOM 1209 C CE1 . HIS B 2 80 ? 38.792 -6.651 18.348 1.00 47.34 ? 79 HIS B CE1 1 ATOM 1210 N NE2 . HIS B 2 80 ? 39.482 -6.145 19.355 1.00 48.97 ? 79 HIS B NE2 1 ATOM 1211 N N . ILE B 2 81 ? 40.028 -12.922 19.182 1.00 45.66 ? 80 ILE B N 1 ATOM 1212 C CA . ILE B 2 81 ? 40.626 -14.248 19.019 1.00 46.71 ? 80 ILE B CA 1 ATOM 1213 C C . ILE B 2 81 ? 40.640 -14.646 17.544 1.00 43.77 ? 80 ILE B C 1 ATOM 1214 O O . ILE B 2 81 ? 39.749 -14.250 16.790 1.00 42.11 ? 80 ILE B O 1 ATOM 1215 C CB . ILE B 2 81 ? 39.918 -15.336 19.866 1.00 49.97 ? 80 ILE B CB 1 ATOM 1216 C CG1 . ILE B 2 81 ? 38.420 -15.391 19.562 1.00 51.60 ? 80 ILE B CG1 1 ATOM 1217 C CG2 . ILE B 2 81 ? 40.149 -15.103 21.360 1.00 50.43 ? 80 ILE B CG2 1 ATOM 1218 C CD1 . ILE B 2 81 ? 37.685 -16.408 20.403 1.00 54.57 ? 80 ILE B CD1 1 ATOM 1219 N N . PRO B 2 82 ? 41.657 -15.428 17.125 1.00 42.32 ? 81 PRO B N 1 ATOM 1220 C CA . PRO B 2 82 ? 41.758 -15.784 15.710 1.00 40.41 ? 81 PRO B CA 1 ATOM 1221 C C . PRO B 2 82 ? 40.564 -16.602 15.261 1.00 37.59 ? 81 PRO B C 1 ATOM 1222 O O . PRO B 2 82 ? 40.149 -17.507 15.978 1.00 37.12 ? 81 PRO B O 1 ATOM 1223 C CB . PRO B 2 82 ? 43.037 -16.631 15.642 1.00 40.72 ? 81 PRO B CB 1 ATOM 1224 C CG . PRO B 2 82 ? 43.760 -16.361 16.916 1.00 41.42 ? 81 PRO B CG 1 ATOM 1225 C CD . PRO B 2 82 ? 42.684 -16.128 17.920 1.00 42.19 ? 81 PRO B CD 1 ATOM 1226 N N . SER B 2 83 ? 40.016 -16.278 14.094 1.00 35.54 ? 82 SER B N 1 ATOM 1227 C CA . SER B 2 83 ? 38.834 -16.969 13.587 1.00 35.53 ? 82 SER B CA 1 ATOM 1228 C C . SER B 2 83 ? 39.125 -18.450 13.239 1.00 36.37 ? 82 SER B C 1 ATOM 1229 O O . SER B 2 83 ? 38.199 -19.263 13.171 1.00 36.83 ? 82 SER B O 1 ATOM 1230 C CB . SER B 2 83 ? 38.228 -16.210 12.392 1.00 34.60 ? 82 SER B CB 1 ATOM 1231 O OG . SER B 2 83 ? 39.177 -16.013 11.364 1.00 33.58 ? 82 SER B OG 1 ATOM 1232 N N . GLU B 2 84 ? 40.402 -18.796 13.054 1.00 35.81 ? 83 GLU B N 1 ATOM 1233 C CA . GLU B 2 84 ? 40.815 -20.192 12.866 1.00 36.41 ? 83 GLU B CA 1 ATOM 1234 C C . GLU B 2 84 ? 40.474 -21.096 14.067 1.00 37.56 ? 83 GLU B C 1 ATOM 1235 O O . GLU B 2 84 ? 40.238 -22.291 13.886 1.00 40.16 ? 83 GLU B O 1 ATOM 1236 C CB . GLU B 2 84 ? 42.324 -20.305 12.577 1.00 35.42 ? 83 GLU B CB 1 ATOM 1237 C CG . GLU B 2 84 ? 42.798 -19.631 11.294 1.00 34.55 ? 83 GLU B CG 1 ATOM 1238 C CD . GLU B 2 84 ? 43.254 -18.189 11.483 1.00 35.44 ? 83 GLU B CD 1 ATOM 1239 O OE1 . GLU B 2 84 ? 44.018 -17.686 10.634 1.00 35.26 ? 83 GLU B OE1 1 ATOM 1240 O OE2 . GLU B 2 84 ? 42.848 -17.543 12.475 1.00 36.03 ? 83 GLU B OE2 1 ATOM 1241 N N . LYS B 2 85 ? 40.440 -20.536 15.275 1.00 36.80 ? 84 LYS B N 1 ATOM 1242 C CA . LYS B 2 85 ? 40.269 -21.335 16.489 1.00 36.87 ? 84 LYS B CA 1 ATOM 1243 C C . LYS B 2 85 ? 38.826 -21.694 16.852 1.00 37.54 ? 84 LYS B C 1 ATOM 1244 O O . LYS B 2 85 ? 38.623 -22.624 17.637 1.00 39.18 ? 84 LYS B O 1 ATOM 1245 C CB . LYS B 2 85 ? 40.928 -20.641 17.680 1.00 36.62 ? 84 LYS B CB 1 ATOM 1246 C CG . LYS B 2 85 ? 42.391 -20.289 17.433 1.00 37.50 ? 84 LYS B CG 1 ATOM 1247 C CD . LYS B 2 85 ? 43.282 -20.560 18.630 1.00 37.09 ? 84 LYS B CD 1 ATOM 1248 C CE . LYS B 2 85 ? 42.880 -19.736 19.834 1.00 36.98 ? 84 LYS B CE 1 ATOM 1249 N NZ . LYS B 2 85 ? 43.660 -20.189 21.008 1.00 37.52 ? 84 LYS B NZ 1 ATOM 1250 N N . ILE B 2 86 ? 37.835 -20.988 16.304 1.00 36.86 ? 85 ILE B N 1 ATOM 1251 C CA . ILE B 2 86 ? 36.424 -21.238 16.669 1.00 37.29 ? 85 ILE B CA 1 ATOM 1252 C C . ILE B 2 86 ? 35.619 -21.964 15.589 1.00 36.67 ? 85 ILE B C 1 ATOM 1253 O O . ILE B 2 86 ? 36.029 -22.032 14.427 1.00 37.27 ? 85 ILE B O 1 ATOM 1254 C CB . ILE B 2 86 ? 35.673 -19.944 17.088 1.00 36.84 ? 85 ILE B CB 1 ATOM 1255 C CG1 . ILE B 2 86 ? 35.601 -18.928 15.948 1.00 37.49 ? 85 ILE B CG1 1 ATOM 1256 C CG2 . ILE B 2 86 ? 36.332 -19.330 18.313 1.00 36.85 ? 85 ILE B CG2 1 ATOM 1257 C CD1 . ILE B 2 86 ? 34.563 -17.855 16.180 1.00 38.81 ? 85 ILE B CD1 1 ATOM 1258 N N . TRP B 2 87 ? 34.469 -22.504 15.991 1.00 35.54 ? 86 TRP B N 1 ATOM 1259 C CA . TRP B 2 87 ? 33.469 -22.964 15.036 1.00 35.86 ? 86 TRP B CA 1 ATOM 1260 C C . TRP B 2 87 ? 32.993 -21.780 14.214 1.00 36.10 ? 86 TRP B C 1 ATOM 1261 O O . TRP B 2 87 ? 32.891 -20.665 14.729 1.00 36.23 ? 86 TRP B O 1 ATOM 1262 C CB . TRP B 2 87 ? 32.267 -23.600 15.740 1.00 35.81 ? 86 TRP B CB 1 ATOM 1263 C CG . TRP B 2 87 ? 31.170 -23.987 14.789 1.00 35.49 ? 86 TRP B CG 1 ATOM 1264 C CD1 . TRP B 2 87 ? 31.041 -25.170 14.127 1.00 35.70 ? 86 TRP B CD1 1 ATOM 1265 C CD2 . TRP B 2 87 ? 30.072 -23.170 14.369 1.00 35.86 ? 86 TRP B CD2 1 ATOM 1266 N NE1 . TRP B 2 87 ? 29.923 -25.147 13.329 1.00 35.95 ? 86 TRP B NE1 1 ATOM 1267 C CE2 . TRP B 2 87 ? 29.310 -23.929 13.458 1.00 35.85 ? 86 TRP B CE2 1 ATOM 1268 C CE3 . TRP B 2 87 ? 29.658 -21.865 14.675 1.00 36.46 ? 86 TRP B CE3 1 ATOM 1269 C CZ2 . TRP B 2 87 ? 28.150 -23.432 12.853 1.00 35.83 ? 86 TRP B CZ2 1 ATOM 1270 C CZ3 . TRP B 2 87 ? 28.503 -21.368 14.070 1.00 36.16 ? 86 TRP B CZ3 1 ATOM 1271 C CH2 . TRP B 2 87 ? 27.764 -22.155 13.170 1.00 35.76 ? 86 TRP B CH2 1 ATOM 1272 N N . ARG B 2 88 ? 32.706 -22.033 12.939 1.00 36.88 ? 87 ARG B N 1 ATOM 1273 C CA . ARG B 2 88 ? 32.148 -21.029 12.039 1.00 37.71 ? 87 ARG B CA 1 ATOM 1274 C C . ARG B 2 88 ? 31.092 -21.674 11.150 1.00 37.87 ? 87 ARG B C 1 ATOM 1275 O O . ARG B 2 88 ? 31.220 -22.846 10.797 1.00 37.39 ? 87 ARG B O 1 ATOM 1276 C CB . ARG B 2 88 ? 33.242 -20.431 11.159 1.00 39.27 ? 87 ARG B CB 1 ATOM 1277 C CG . ARG B 2 88 ? 34.490 -19.992 11.908 1.00 41.42 ? 87 ARG B CG 1 ATOM 1278 C CD . ARG B 2 88 ? 35.504 -19.398 10.958 1.00 44.42 ? 87 ARG B CD 1 ATOM 1279 N NE . ARG B 2 88 ? 36.031 -20.391 10.018 1.00 47.90 ? 87 ARG B NE 1 ATOM 1280 C CZ . ARG B 2 88 ? 36.959 -21.314 10.296 1.00 48.95 ? 87 ARG B CZ 1 ATOM 1281 N NH1 . ARG B 2 88 ? 37.502 -21.419 11.511 1.00 50.19 ? 87 ARG B NH1 1 ATOM 1282 N NH2 . ARG B 2 88 ? 37.347 -22.152 9.339 1.00 49.16 ? 87 ARG B NH2 1 ATOM 1283 N N . PRO B 2 89 ? 30.058 -20.906 10.757 1.00 39.31 ? 88 PRO B N 1 ATOM 1284 C CA . PRO B 2 89 ? 29.036 -21.439 9.852 1.00 40.02 ? 88 PRO B CA 1 ATOM 1285 C C . PRO B 2 89 ? 29.513 -21.683 8.419 1.00 40.77 ? 88 PRO B C 1 ATOM 1286 O O . PRO B 2 89 ? 28.806 -22.334 7.661 1.00 44.24 ? 88 PRO B O 1 ATOM 1287 C CB . PRO B 2 89 ? 27.956 -20.358 9.879 1.00 39.43 ? 88 PRO B CB 1 ATOM 1288 C CG . PRO B 2 89 ? 28.708 -19.109 10.127 1.00 39.52 ? 88 PRO B CG 1 ATOM 1289 C CD . PRO B 2 89 ? 29.791 -19.495 11.092 1.00 39.68 ? 88 PRO B CD 1 ATOM 1290 N N . ASP B 2 90 ? 30.682 -21.151 8.060 1.00 42.41 ? 89 ASP B N 1 ATOM 1291 C CA . ASP B 2 90 ? 31.313 -21.338 6.747 1.00 42.07 ? 89 ASP B CA 1 ATOM 1292 C C . ASP B 2 90 ? 30.476 -20.731 5.607 1.00 41.24 ? 89 ASP B C 1 ATOM 1293 O O . ASP B 2 90 ? 30.186 -21.376 4.595 1.00 40.55 ? 89 ASP B O 1 ATOM 1294 C CB . ASP B 2 90 ? 31.677 -22.811 6.505 1.00 43.93 ? 89 ASP B CB 1 ATOM 1295 C CG . ASP B 2 90 ? 32.783 -22.986 5.465 1.00 47.75 ? 89 ASP B CG 1 ATOM 1296 O OD1 . ASP B 2 90 ? 33.502 -22.002 5.174 1.00 49.44 ? 89 ASP B OD1 1 ATOM 1297 O OD2 . ASP B 2 90 ? 32.930 -24.117 4.931 1.00 51.08 ? 89 ASP B OD2 1 ATOM 1298 N N . VAL B 2 91 ? 30.112 -19.464 5.796 1.00 40.57 ? 90 VAL B N 1 ATOM 1299 C CA . VAL B 2 91 ? 29.407 -18.684 4.788 1.00 39.50 ? 90 VAL B CA 1 ATOM 1300 C C . VAL B 2 91 ? 30.416 -18.353 3.695 1.00 40.00 ? 90 VAL B C 1 ATOM 1301 O O . VAL B 2 91 ? 31.536 -17.944 3.989 1.00 41.18 ? 90 VAL B O 1 ATOM 1302 C CB . VAL B 2 91 ? 28.816 -17.384 5.383 1.00 38.89 ? 90 VAL B CB 1 ATOM 1303 C CG1 . VAL B 2 91 ? 28.178 -16.521 4.300 1.00 39.14 ? 90 VAL B CG1 1 ATOM 1304 C CG2 . VAL B 2 91 ? 27.803 -17.711 6.478 1.00 38.86 ? 90 VAL B CG2 1 ATOM 1305 N N . VAL B 2 92 ? 30.021 -18.553 2.442 1.00 42.06 ? 91 VAL B N 1 ATOM 1306 C CA . VAL B 2 92 ? 30.907 -18.340 1.295 1.00 44.05 ? 91 VAL B CA 1 ATOM 1307 C C . VAL B 2 92 ? 30.187 -17.521 0.245 1.00 45.36 ? 91 VAL B C 1 ATOM 1308 O O . VAL B 2 92 ? 28.957 -17.529 0.186 1.00 44.84 ? 91 VAL B O 1 ATOM 1309 C CB . VAL B 2 92 ? 31.407 -19.671 0.654 1.00 44.28 ? 91 VAL B CB 1 ATOM 1310 C CG1 . VAL B 2 92 ? 32.329 -20.422 1.609 1.00 43.76 ? 91 VAL B CG1 1 ATOM 1311 C CG2 . VAL B 2 92 ? 30.252 -20.573 0.222 1.00 43.63 ? 91 VAL B CG2 1 ATOM 1312 N N . LEU B 2 93 ? 30.977 -16.819 -0.564 1.00 47.48 ? 92 LEU B N 1 ATOM 1313 C CA . LEU B 2 93 ? 30.496 -16.082 -1.722 1.00 49.28 ? 92 LEU B CA 1 ATOM 1314 C C . LEU B 2 93 ? 30.641 -16.993 -2.938 1.00 48.26 ? 92 LEU B C 1 ATOM 1315 O O . LEU B 2 93 ? 31.633 -17.706 -3.058 1.00 45.78 ? 92 LEU B O 1 ATOM 1316 C CB . LEU B 2 93 ? 31.325 -14.802 -1.940 1.00 54.40 ? 92 LEU B CB 1 ATOM 1317 C CG . LEU B 2 93 ? 31.009 -13.491 -1.199 1.00 57.31 ? 92 LEU B CG 1 ATOM 1318 C CD1 . LEU B 2 93 ? 32.197 -12.529 -1.233 1.00 57.87 ? 92 LEU B CD1 1 ATOM 1319 C CD2 . LEU B 2 93 ? 29.788 -12.815 -1.812 1.00 59.38 ? 92 LEU B CD2 1 ATOM 1320 N N . TYR B 2 94 ? 29.663 -16.963 -3.840 1.00 49.54 ? 93 TYR B N 1 ATOM 1321 C CA . TYR B 2 94 ? 29.717 -17.756 -5.083 1.00 49.35 ? 93 TYR B CA 1 ATOM 1322 C C . TYR B 2 94 ? 28.931 -17.066 -6.224 1.00 52.96 ? 93 TYR B C 1 ATOM 1323 O O . TYR B 2 94 ? 28.427 -15.967 -6.035 1.00 50.42 ? 93 TYR B O 1 ATOM 1324 C CB . TYR B 2 94 ? 29.266 -19.199 -4.810 1.00 45.37 ? 93 TYR B CB 1 ATOM 1325 C CG . TYR B 2 94 ? 27.858 -19.337 -4.281 1.00 43.89 ? 93 TYR B CG 1 ATOM 1326 C CD1 . TYR B 2 94 ? 27.598 -19.296 -2.918 1.00 42.96 ? 93 TYR B CD1 1 ATOM 1327 C CD2 . TYR B 2 94 ? 26.789 -19.540 -5.143 1.00 43.27 ? 93 TYR B CD2 1 ATOM 1328 C CE1 . TYR B 2 94 ? 26.309 -19.432 -2.432 1.00 43.33 ? 93 TYR B CE1 1 ATOM 1329 C CE2 . TYR B 2 94 ? 25.497 -19.680 -4.668 1.00 42.87 ? 93 TYR B CE2 1 ATOM 1330 C CZ . TYR B 2 94 ? 25.260 -19.623 -3.314 1.00 43.75 ? 93 TYR B CZ 1 ATOM 1331 O OH . TYR B 2 94 ? 23.971 -19.763 -2.846 1.00 46.79 ? 93 TYR B OH 1 ATOM 1332 N N . ASN B 2 95 ? 28.799 -17.746 -7.365 1.00 59.74 ? 94 ASN B N 1 ATOM 1333 C CA . ASN B 2 95 ? 28.642 -17.143 -8.712 1.00 63.88 ? 94 ASN B CA 1 ATOM 1334 C C . ASN B 2 95 ? 29.813 -16.196 -9.054 1.00 66.75 ? 94 ASN B C 1 ATOM 1335 O O . ASN B 2 95 ? 29.647 -15.121 -9.620 1.00 64.32 ? 94 ASN B O 1 ATOM 1336 C CB . ASN B 2 95 ? 27.188 -16.667 -9.043 1.00 66.55 ? 94 ASN B CB 1 ATOM 1337 C CG . ASN B 2 95 ? 26.822 -15.272 -8.524 1.00 70.10 ? 94 ASN B CG 1 ATOM 1338 O OD1 . ASN B 2 95 ? 27.586 -14.595 -7.842 1.00 74.14 ? 94 ASN B OD1 1 ATOM 1339 N ND2 . ASN B 2 95 ? 25.609 -14.840 -8.865 1.00 68.30 ? 94 ASN B ND2 1 ATOM 1340 N N . ASN B 2 96 ? 31.014 -16.666 -8.712 1.00 75.10 ? 95 ASN B N 1 ATOM 1341 C CA . ASN B 2 96 ? 32.278 -15.967 -8.954 1.00 78.37 ? 95 ASN B CA 1 ATOM 1342 C C . ASN B 2 96 ? 32.771 -16.338 -10.358 1.00 83.75 ? 95 ASN B C 1 ATOM 1343 O O . ASN B 2 96 ? 32.700 -17.508 -10.754 1.00 84.66 ? 95 ASN B O 1 ATOM 1344 C CB . ASN B 2 96 ? 33.299 -16.385 -7.880 1.00 75.67 ? 95 ASN B CB 1 ATOM 1345 C CG . ASN B 2 96 ? 34.485 -15.438 -7.781 1.00 74.83 ? 95 ASN B CG 1 ATOM 1346 O OD1 . ASN B 2 96 ? 35.216 -15.235 -8.746 1.00 75.85 ? 95 ASN B OD1 1 ATOM 1347 N ND2 . ASN B 2 96 ? 34.692 -14.870 -6.600 1.00 72.69 ? 95 ASN B ND2 1 ATOM 1348 N N . ALA B 2 97 ? 33.276 -15.348 -11.096 1.00 88.95 ? 96 ALA B N 1 ATOM 1349 C CA . ALA B 2 97 ? 33.641 -15.526 -12.510 1.00 94.35 ? 96 ALA B CA 1 ATOM 1350 C C . ALA B 2 97 ? 34.941 -16.323 -12.711 1.00 98.72 ? 96 ALA B C 1 ATOM 1351 O O . ALA B 2 97 ? 34.975 -17.235 -13.541 1.00 95.86 ? 96 ALA B O 1 ATOM 1352 C CB . ALA B 2 97 ? 33.732 -14.177 -13.207 1.00 96.50 ? 96 ALA B CB 1 ATOM 1353 N N . ASP B 2 98 ? 35.995 -15.964 -11.967 1.00 103.43 ? 97 ASP B N 1 ATOM 1354 C CA . ASP B 2 98 ? 37.292 -16.678 -11.988 1.00 106.70 ? 97 ASP B CA 1 ATOM 1355 C C . ASP B 2 98 ? 37.634 -17.260 -10.602 1.00 105.18 ? 97 ASP B C 1 ATOM 1356 O O . ASP B 2 98 ? 38.191 -16.559 -9.746 1.00 103.05 ? 97 ASP B O 1 ATOM 1357 C CB . ASP B 2 98 ? 38.422 -15.741 -12.453 1.00 110.58 ? 97 ASP B CB 1 ATOM 1358 C CG . ASP B 2 98 ? 38.318 -15.360 -13.932 1.00 113.40 ? 97 ASP B CG 1 ATOM 1359 O OD1 . ASP B 2 98 ? 38.027 -16.240 -14.777 1.00 110.00 ? 97 ASP B OD1 1 ATOM 1360 O OD2 . ASP B 2 98 ? 38.553 -14.173 -14.252 1.00 112.70 ? 97 ASP B OD2 1 ATOM 1361 N N . GLY B 2 99 ? 37.308 -18.542 -10.403 1.00 102.99 ? 98 GLY B N 1 ATOM 1362 C CA . GLY B 2 99 ? 37.481 -19.236 -9.112 1.00 100.08 ? 98 GLY B CA 1 ATOM 1363 C C . GLY B 2 99 ? 36.167 -19.284 -8.343 1.00 96.71 ? 98 GLY B C 1 ATOM 1364 O O . GLY B 2 99 ? 35.875 -18.375 -7.563 1.00 101.63 ? 98 GLY B O 1 ATOM 1365 N N . ASP B 2 100 ? 35.403 -20.362 -8.544 1.00 86.65 ? 99 ASP B N 1 ATOM 1366 C CA . ASP B 2 100 ? 33.971 -20.442 -8.159 1.00 80.05 ? 99 ASP B CA 1 ATOM 1367 C C . ASP B 2 100 ? 33.567 -19.954 -6.751 1.00 72.37 ? 99 ASP B C 1 ATOM 1368 O O . ASP B 2 100 ? 32.560 -19.253 -6.625 1.00 72.27 ? 99 ASP B O 1 ATOM 1369 C CB . ASP B 2 100 ? 33.429 -21.869 -8.386 1.00 80.17 ? 99 ASP B CB 1 ATOM 1370 C CG . ASP B 2 100 ? 32.855 -22.085 -9.797 1.00 82.35 ? 99 ASP B CG 1 ATOM 1371 O OD1 . ASP B 2 100 ? 32.738 -21.124 -10.598 1.00 82.03 ? 99 ASP B OD1 1 ATOM 1372 O OD2 . ASP B 2 100 ? 32.504 -23.243 -10.103 1.00 82.19 ? 99 ASP B OD2 1 ATOM 1373 N N . PHE B 2 101 ? 34.318 -20.330 -5.715 1.00 63.42 ? 100 PHE B N 1 ATOM 1374 C CA . PHE B 2 101 ? 34.140 -19.750 -4.371 1.00 58.92 ? 100 PHE B CA 1 ATOM 1375 C C . PHE B 2 101 ? 35.178 -18.657 -4.112 1.00 56.58 ? 100 PHE B C 1 ATOM 1376 O O . PHE B 2 101 ? 36.344 -18.806 -4.480 1.00 58.85 ? 100 PHE B O 1 ATOM 1377 C CB . PHE B 2 101 ? 34.223 -20.824 -3.282 1.00 58.16 ? 100 PHE B CB 1 ATOM 1378 C CG . PHE B 2 101 ? 33.061 -21.781 -3.287 1.00 59.45 ? 100 PHE B CG 1 ATOM 1379 C CD1 . PHE B 2 101 ? 31.814 -21.384 -2.823 1.00 59.95 ? 100 PHE B CD1 1 ATOM 1380 C CD2 . PHE B 2 101 ? 33.207 -23.080 -3.765 1.00 60.08 ? 100 PHE B CD2 1 ATOM 1381 C CE1 . PHE B 2 101 ? 30.736 -22.262 -2.842 1.00 60.50 ? 100 PHE B CE1 1 ATOM 1382 C CE2 . PHE B 2 101 ? 32.136 -23.961 -3.778 1.00 58.84 ? 100 PHE B CE2 1 ATOM 1383 C CZ . PHE B 2 101 ? 30.900 -23.553 -3.317 1.00 58.52 ? 100 PHE B CZ 1 ATOM 1384 N N . ALA B 2 102 ? 34.754 -17.561 -3.484 1.00 52.65 ? 101 ALA B N 1 ATOM 1385 C CA . ALA B 2 102 ? 35.664 -16.467 -3.148 1.00 51.69 ? 101 ALA B CA 1 ATOM 1386 C C . ALA B 2 102 ? 36.469 -16.816 -1.899 1.00 52.58 ? 101 ALA B C 1 ATOM 1387 O O . ALA B 2 102 ? 35.911 -17.304 -0.924 1.00 52.96 ? 101 ALA B O 1 ATOM 1388 C CB . ALA B 2 102 ? 34.893 -15.178 -2.935 1.00 50.96 ? 101 ALA B CB 1 ATOM 1389 N N . ILE B 2 103 ? 37.775 -16.563 -1.937 1.00 56.10 ? 102 ILE B N 1 ATOM 1390 C CA . ILE B 2 103 ? 38.651 -16.786 -0.787 1.00 59.68 ? 102 ILE B CA 1 ATOM 1391 C C . ILE B 2 103 ? 38.564 -15.546 0.118 1.00 58.31 ? 102 ILE B C 1 ATOM 1392 O O . ILE B 2 103 ? 38.835 -14.424 -0.319 1.00 60.10 ? 102 ILE B O 1 ATOM 1393 C CB . ILE B 2 103 ? 40.112 -17.112 -1.220 1.00 63.38 ? 102 ILE B CB 1 ATOM 1394 C CG1 . ILE B 2 103 ? 40.132 -18.400 -2.062 1.00 68.10 ? 102 ILE B CG1 1 ATOM 1395 C CG2 . ILE B 2 103 ? 41.030 -17.300 -0.010 1.00 63.82 ? 102 ILE B CG2 1 ATOM 1396 C CD1 . ILE B 2 103 ? 41.484 -18.781 -2.639 1.00 70.19 ? 102 ILE B CD1 1 ATOM 1397 N N . VAL B 2 104 ? 38.169 -15.770 1.371 1.00 56.44 ? 103 VAL B N 1 ATOM 1398 C CA . VAL B 2 104 ? 37.974 -14.716 2.365 1.00 55.13 ? 103 VAL B CA 1 ATOM 1399 C C . VAL B 2 104 ? 39.096 -14.793 3.395 1.00 54.20 ? 103 VAL B C 1 ATOM 1400 O O . VAL B 2 104 ? 39.344 -15.868 3.945 1.00 55.25 ? 103 VAL B O 1 ATOM 1401 C CB . VAL B 2 104 ? 36.632 -14.900 3.101 1.00 55.49 ? 103 VAL B CB 1 ATOM 1402 C CG1 . VAL B 2 104 ? 36.274 -13.648 3.882 1.00 56.98 ? 103 VAL B CG1 1 ATOM 1403 C CG2 . VAL B 2 104 ? 35.515 -15.246 2.118 1.00 56.83 ? 103 VAL B CG2 1 ATOM 1404 N N . LYS B 2 105 ? 39.757 -13.660 3.663 1.00 51.59 ? 104 LYS B N 1 ATOM 1405 C CA . LYS B 2 105 ? 40.836 -13.595 4.662 1.00 48.28 ? 104 LYS B CA 1 ATOM 1406 C C . LYS B 2 105 ? 40.295 -13.826 6.064 1.00 46.29 ? 104 LYS B C 1 ATOM 1407 O O . LYS B 2 105 ? 39.250 -13.296 6.416 1.00 47.07 ? 104 LYS B O 1 ATOM 1408 C CB . LYS B 2 105 ? 41.550 -12.243 4.633 1.00 48.51 ? 104 LYS B CB 1 ATOM 1409 C CG . LYS B 2 105 ? 42.785 -12.205 5.521 1.00 49.91 ? 104 LYS B CG 1 ATOM 1410 C CD . LYS B 2 105 ? 43.514 -10.875 5.474 1.00 51.20 ? 104 LYS B CD 1 ATOM 1411 C CE . LYS B 2 105 ? 44.630 -10.840 6.511 1.00 52.83 ? 104 LYS B CE 1 ATOM 1412 N NZ . LYS B 2 105 ? 45.375 -9.551 6.491 1.00 54.87 ? 104 LYS B NZ 1 ATOM 1413 N N . PHE B 2 106 ? 41.023 -14.602 6.859 1.00 45.01 ? 105 PHE B N 1 ATOM 1414 C CA . PHE B 2 106 ? 40.613 -14.936 8.228 1.00 44.83 ? 105 PHE B CA 1 ATOM 1415 C C . PHE B 2 106 ? 41.203 -13.938 9.234 1.00 41.68 ? 105 PHE B C 1 ATOM 1416 O O . PHE B 2 106 ? 42.221 -14.188 9.875 1.00 40.47 ? 105 PHE B O 1 ATOM 1417 C CB . PHE B 2 106 ? 40.992 -16.392 8.560 1.00 47.04 ? 105 PHE B CB 1 ATOM 1418 C CG . PHE B 2 106 ? 40.081 -17.433 7.936 1.00 50.45 ? 105 PHE B CG 1 ATOM 1419 C CD1 . PHE B 2 106 ? 39.157 -17.123 6.925 1.00 53.01 ? 105 PHE B CD1 1 ATOM 1420 C CD2 . PHE B 2 106 ? 40.163 -18.747 8.357 1.00 52.93 ? 105 PHE B CD2 1 ATOM 1421 C CE1 . PHE B 2 106 ? 38.339 -18.099 6.380 1.00 54.78 ? 105 PHE B CE1 1 ATOM 1422 C CE2 . PHE B 2 106 ? 39.349 -19.729 7.807 1.00 54.50 ? 105 PHE B CE2 1 ATOM 1423 C CZ . PHE B 2 106 ? 38.439 -19.407 6.818 1.00 54.77 ? 105 PHE B CZ 1 ATOM 1424 N N . THR B 2 107 ? 40.538 -12.792 9.342 1.00 39.55 ? 106 THR B N 1 ATOM 1425 C CA . THR B 2 107 ? 40.824 -11.802 10.371 1.00 38.90 ? 106 THR B CA 1 ATOM 1426 C C . THR B 2 107 ? 40.317 -12.306 11.710 1.00 39.09 ? 106 THR B C 1 ATOM 1427 O O . THR B 2 107 ? 39.521 -13.238 11.770 1.00 41.49 ? 106 THR B O 1 ATOM 1428 C CB . THR B 2 107 ? 40.113 -10.467 10.078 1.00 38.21 ? 106 THR B CB 1 ATOM 1429 O OG1 . THR B 2 107 ? 38.705 -10.696 9.929 1.00 37.75 ? 106 THR B OG1 1 ATOM 1430 C CG2 . THR B 2 107 ? 40.669 -9.820 8.811 1.00 37.74 ? 106 THR B CG2 1 ATOM 1431 N N . LYS B 2 108 ? 40.747 -11.660 12.785 1.00 39.84 ? 107 LYS B N 1 ATOM 1432 C CA . LYS B 2 108 ? 40.300 -12.034 14.124 1.00 40.19 ? 107 LYS B CA 1 ATOM 1433 C C . LYS B 2 108 ? 38.827 -11.662 14.318 1.00 37.36 ? 107 LYS B C 1 ATOM 1434 O O . LYS B 2 108 ? 38.281 -10.851 13.569 1.00 34.57 ? 107 LYS B O 1 ATOM 1435 C CB . LYS B 2 108 ? 41.193 -11.399 15.194 1.00 43.30 ? 107 LYS B CB 1 ATOM 1436 C CG . LYS B 2 108 ? 42.669 -11.784 15.042 1.00 47.89 ? 107 LYS B CG 1 ATOM 1437 C CD . LYS B 2 108 ? 43.293 -12.385 16.304 1.00 52.61 ? 107 LYS B CD 1 ATOM 1438 C CE . LYS B 2 108 ? 43.893 -11.348 17.247 1.00 55.09 ? 107 LYS B CE 1 ATOM 1439 N NZ . LYS B 2 108 ? 45.189 -10.814 16.739 1.00 58.55 ? 107 LYS B NZ 1 ATOM 1440 N N . VAL B 2 109 ? 38.189 -12.308 15.292 1.00 36.00 ? 108 VAL B N 1 ATOM 1441 C CA . VAL B 2 109 ? 36.802 -12.022 15.664 1.00 35.65 ? 108 VAL B CA 1 ATOM 1442 C C . VAL B 2 109 ? 36.782 -11.184 16.941 1.00 35.09 ? 108 VAL B C 1 ATOM 1443 O O . VAL B 2 109 ? 37.716 -11.254 17.741 1.00 33.23 ? 108 VAL B O 1 ATOM 1444 C CB . VAL B 2 109 ? 35.956 -13.319 15.865 1.00 37.21 ? 108 VAL B CB 1 ATOM 1445 C CG1 . VAL B 2 109 ? 36.079 -14.244 14.665 1.00 37.76 ? 108 VAL B CG1 1 ATOM 1446 C CG2 . VAL B 2 109 ? 36.317 -14.078 17.144 1.00 36.95 ? 108 VAL B CG2 1 ATOM 1447 N N . LEU B 2 110 ? 35.726 -10.388 17.107 1.00 35.45 ? 109 LEU B N 1 ATOM 1448 C CA . LEU B 2 110 ? 35.402 -9.739 18.381 1.00 35.94 ? 109 LEU B CA 1 ATOM 1449 C C . LEU B 2 110 ? 34.477 -10.691 19.129 1.00 35.23 ? 109 LEU B C 1 ATOM 1450 O O . LEU B 2 110 ? 33.380 -10.979 18.655 1.00 36.04 ? 109 LEU B O 1 ATOM 1451 C CB . LEU B 2 110 ? 34.697 -8.389 18.158 1.00 36.63 ? 109 LEU B CB 1 ATOM 1452 C CG . LEU B 2 110 ? 34.267 -7.579 19.400 1.00 36.76 ? 109 LEU B CG 1 ATOM 1453 C CD1 . LEU B 2 110 ? 35.475 -7.042 20.153 1.00 36.20 ? 109 LEU B CD1 1 ATOM 1454 C CD2 . LEU B 2 110 ? 33.314 -6.441 19.034 1.00 36.16 ? 109 LEU B CD2 1 ATOM 1455 N N . LEU B 2 111 ? 34.934 -11.185 20.279 1.00 34.87 ? 110 LEU B N 1 ATOM 1456 C CA . LEU B 2 111 ? 34.123 -12.019 21.167 1.00 34.98 ? 110 LEU B CA 1 ATOM 1457 C C . LEU B 2 111 ? 33.794 -11.204 22.407 1.00 35.57 ? 110 LEU B C 1 ATOM 1458 O O . LEU B 2 111 ? 34.616 -10.410 22.852 1.00 35.94 ? 110 LEU B O 1 ATOM 1459 C CB . LEU B 2 111 ? 34.887 -13.282 21.565 1.00 34.13 ? 110 LEU B CB 1 ATOM 1460 C CG . LEU B 2 111 ? 34.221 -14.250 22.557 1.00 33.14 ? 110 LEU B CG 1 ATOM 1461 C CD1 . LEU B 2 111 ? 32.990 -14.927 21.975 1.00 33.32 ? 110 LEU B CD1 1 ATOM 1462 C CD2 . LEU B 2 111 ? 35.225 -15.292 23.016 1.00 33.08 ? 110 LEU B CD2 1 ATOM 1463 N N . ASP B 2 112 ? 32.602 -11.404 22.962 1.00 35.62 ? 111 ASP B N 1 ATOM 1464 C CA . ASP B 2 112 ? 32.254 -10.785 24.232 1.00 37.12 ? 111 ASP B CA 1 ATOM 1465 C C . ASP B 2 112 ? 31.722 -11.810 25.231 1.00 37.23 ? 111 ASP B C 1 ATOM 1466 O O . ASP B 2 112 ? 31.437 -12.959 24.867 1.00 36.50 ? 111 ASP B O 1 ATOM 1467 C CB . ASP B 2 112 ? 31.325 -9.559 24.028 1.00 38.38 ? 111 ASP B CB 1 ATOM 1468 C CG . ASP B 2 112 ? 29.838 -9.914 23.859 1.00 39.62 ? 111 ASP B CG 1 ATOM 1469 O OD1 . ASP B 2 112 ? 29.352 -10.946 24.376 1.00 39.38 ? 111 ASP B OD1 1 ATOM 1470 O OD2 . ASP B 2 112 ? 29.132 -9.103 23.221 1.00 41.05 ? 111 ASP B OD2 1 ATOM 1471 N N . TYR B 2 113 ? 31.600 -11.371 26.484 1.00 37.12 ? 112 TYR B N 1 ATOM 1472 C CA . TYR B 2 113 ? 31.285 -12.244 27.628 1.00 37.12 ? 112 TYR B CA 1 ATOM 1473 C C . TYR B 2 113 ? 29.952 -13.006 27.576 1.00 36.88 ? 112 TYR B C 1 ATOM 1474 O O . TYR B 2 113 ? 29.776 -13.965 28.329 1.00 36.25 ? 112 TYR B O 1 ATOM 1475 C CB . TYR B 2 113 ? 31.392 -11.463 28.950 1.00 37.53 ? 112 TYR B CB 1 ATOM 1476 C CG . TYR B 2 113 ? 30.299 -10.438 29.191 1.00 38.28 ? 112 TYR B CG 1 ATOM 1477 C CD1 . TYR B 2 113 ? 30.435 -9.110 28.753 1.00 38.56 ? 112 TYR B CD1 1 ATOM 1478 C CD2 . TYR B 2 113 ? 29.141 -10.782 29.878 1.00 38.05 ? 112 TYR B CD2 1 ATOM 1479 C CE1 . TYR B 2 113 ? 29.435 -8.172 28.976 1.00 38.18 ? 112 TYR B CE1 1 ATOM 1480 C CE2 . TYR B 2 113 ? 28.139 -9.849 30.104 1.00 38.55 ? 112 TYR B CE2 1 ATOM 1481 C CZ . TYR B 2 113 ? 28.288 -8.551 29.652 1.00 38.52 ? 112 TYR B CZ 1 ATOM 1482 O OH . TYR B 2 113 ? 27.289 -7.640 29.890 1.00 39.36 ? 112 TYR B OH 1 ATOM 1483 N N . THR B 2 114 ? 29.027 -12.594 26.705 1.00 37.47 ? 113 THR B N 1 ATOM 1484 C CA . THR B 2 114 ? 27.792 -13.366 26.451 1.00 37.95 ? 113 THR B CA 1 ATOM 1485 C C . THR B 2 114 ? 27.979 -14.450 25.374 1.00 38.79 ? 113 THR B C 1 ATOM 1486 O O . THR B 2 114 ? 27.002 -15.088 24.962 1.00 39.23 ? 113 THR B O 1 ATOM 1487 C CB . THR B 2 114 ? 26.614 -12.456 26.025 1.00 37.33 ? 113 THR B CB 1 ATOM 1488 O OG1 . THR B 2 114 ? 26.851 -11.929 24.717 1.00 37.48 ? 113 THR B OG1 1 ATOM 1489 C CG2 . THR B 2 114 ? 26.436 -11.303 26.997 1.00 38.20 ? 113 THR B CG2 1 ATOM 1490 N N . GLY B 2 115 ? 29.220 -14.653 24.917 1.00 38.26 ? 114 GLY B N 1 ATOM 1491 C CA . GLY B 2 115 ? 29.498 -15.530 23.790 1.00 37.94 ? 114 GLY B CA 1 ATOM 1492 C C . GLY B 2 115 ? 29.139 -14.967 22.422 1.00 37.39 ? 114 GLY B C 1 ATOM 1493 O O . GLY B 2 115 ? 29.151 -15.712 21.444 1.00 37.82 ? 114 GLY B O 1 ATOM 1494 N N . HIS B 2 116 ? 28.834 -13.667 22.334 1.00 36.25 ? 115 HIS B N 1 ATOM 1495 C CA . HIS B 2 116 ? 28.533 -13.047 21.052 1.00 36.01 ? 115 HIS B CA 1 ATOM 1496 C C . HIS B 2 116 ? 29.803 -12.949 20.213 1.00 35.77 ? 115 HIS B C 1 ATOM 1497 O O . HIS B 2 116 ? 30.858 -12.583 20.721 1.00 35.06 ? 115 HIS B O 1 ATOM 1498 C CB . HIS B 2 116 ? 27.929 -11.653 21.218 1.00 35.76 ? 115 HIS B CB 1 ATOM 1499 C CG . HIS B 2 116 ? 27.368 -11.094 19.945 1.00 36.90 ? 115 HIS B CG 1 ATOM 1500 N ND1 . HIS B 2 116 ? 28.116 -10.340 19.067 1.00 37.17 ? 115 HIS B ND1 1 ATOM 1501 C CD2 . HIS B 2 116 ? 26.137 -11.203 19.389 1.00 37.81 ? 115 HIS B CD2 1 ATOM 1502 C CE1 . HIS B 2 116 ? 27.366 -9.995 18.035 1.00 37.26 ? 115 HIS B CE1 1 ATOM 1503 N NE2 . HIS B 2 116 ? 26.160 -10.506 18.205 1.00 37.28 ? 115 HIS B NE2 1 ATOM 1504 N N . ILE B 2 117 ? 29.682 -13.282 18.932 1.00 36.27 ? 116 ILE B N 1 ATOM 1505 C CA . ILE B 2 117 ? 30.771 -13.156 17.974 1.00 36.36 ? 116 ILE B CA 1 ATOM 1506 C C . ILE B 2 117 ? 30.388 -12.123 16.908 1.00 36.25 ? 116 ILE B C 1 ATOM 1507 O O . ILE B 2 117 ? 29.236 -12.061 16.474 1.00 35.01 ? 116 ILE B O 1 ATOM 1508 C CB . ILE B 2 117 ? 31.112 -14.528 17.359 1.00 36.89 ? 116 ILE B CB 1 ATOM 1509 C CG1 . ILE B 2 117 ? 31.751 -15.414 18.437 1.00 37.64 ? 116 ILE B CG1 1 ATOM 1510 C CG2 . ILE B 2 117 ? 32.051 -14.389 16.161 1.00 36.25 ? 116 ILE B CG2 1 ATOM 1511 C CD1 . ILE B 2 117 ? 31.707 -16.894 18.126 1.00 39.15 ? 116 ILE B CD1 1 ATOM 1512 N N . THR B 2 118 ? 31.354 -11.277 16.554 1.00 36.60 ? 117 THR B N 1 ATOM 1513 C CA . THR B 2 118 ? 31.266 -10.402 15.391 1.00 37.84 ? 117 THR B CA 1 ATOM 1514 C C . THR B 2 118 ? 32.527 -10.629 14.579 1.00 37.82 ? 117 THR B C 1 ATOM 1515 O O . THR B 2 118 ? 33.633 -10.579 15.117 1.00 39.26 ? 117 THR B O 1 ATOM 1516 C CB . THR B 2 118 ? 31.183 -8.908 15.767 1.00 39.53 ? 117 THR B CB 1 ATOM 1517 O OG1 . THR B 2 118 ? 29.975 -8.652 16.495 1.00 41.40 ? 117 THR B OG1 1 ATOM 1518 C CG2 . THR B 2 118 ? 31.200 -8.025 14.508 1.00 39.58 ? 117 THR B CG2 1 ATOM 1519 N N . TRP B 2 119 ? 32.351 -10.880 13.288 1.00 36.90 ? 118 TRP B N 1 ATOM 1520 C CA . TRP B 2 119 ? 33.458 -11.191 12.391 1.00 36.36 ? 118 TRP B CA 1 ATOM 1521 C C . TRP B 2 119 ? 33.173 -10.496 11.074 1.00 35.87 ? 118 TRP B C 1 ATOM 1522 O O . TRP B 2 119 ? 32.061 -10.580 10.553 1.00 34.89 ? 118 TRP B O 1 ATOM 1523 C CB . TRP B 2 119 ? 33.560 -12.706 12.215 1.00 35.93 ? 118 TRP B CB 1 ATOM 1524 C CG . TRP B 2 119 ? 34.740 -13.202 11.439 1.00 35.67 ? 118 TRP B CG 1 ATOM 1525 C CD1 . TRP B 2 119 ? 36.002 -12.680 11.419 1.00 35.69 ? 118 TRP B CD1 1 ATOM 1526 C CD2 . TRP B 2 119 ? 34.771 -14.353 10.595 1.00 35.92 ? 118 TRP B CD2 1 ATOM 1527 N NE1 . TRP B 2 119 ? 36.811 -13.429 10.597 1.00 35.02 ? 118 TRP B NE1 1 ATOM 1528 C CE2 . TRP B 2 119 ? 36.079 -14.462 10.081 1.00 35.00 ? 118 TRP B CE2 1 ATOM 1529 C CE3 . TRP B 2 119 ? 33.812 -15.303 10.214 1.00 36.65 ? 118 TRP B CE3 1 ATOM 1530 C CZ2 . TRP B 2 119 ? 36.453 -15.476 9.207 1.00 35.80 ? 118 TRP B CZ2 1 ATOM 1531 C CZ3 . TRP B 2 119 ? 34.185 -16.311 9.337 1.00 36.17 ? 118 TRP B CZ3 1 ATOM 1532 C CH2 . TRP B 2 119 ? 35.495 -16.390 8.846 1.00 35.90 ? 118 TRP B CH2 1 ATOM 1533 N N . THR B 2 120 ? 34.177 -9.802 10.556 1.00 35.94 ? 119 THR B N 1 ATOM 1534 C CA . THR B 2 120 ? 34.011 -8.919 9.414 1.00 37.33 ? 119 THR B CA 1 ATOM 1535 C C . THR B 2 120 ? 35.176 -9.135 8.442 1.00 38.36 ? 119 THR B C 1 ATOM 1536 O O . THR B 2 120 ? 35.906 -8.192 8.111 1.00 40.00 ? 119 THR B O 1 ATOM 1537 C CB . THR B 2 120 ? 33.941 -7.446 9.887 1.00 37.62 ? 119 THR B CB 1 ATOM 1538 O OG1 . THR B 2 120 ? 33.131 -7.356 11.064 1.00 38.70 ? 119 THR B OG1 1 ATOM 1539 C CG2 . THR B 2 120 ? 33.352 -6.541 8.809 1.00 38.38 ? 119 THR B CG2 1 ATOM 1540 N N . PRO B 2 121 ? 35.351 -10.386 7.970 1.00 37.78 ? 120 PRO B N 1 ATOM 1541 C CA . PRO B 2 121 ? 36.512 -10.721 7.158 1.00 37.31 ? 120 PRO B CA 1 ATOM 1542 C C . PRO B 2 121 ? 36.439 -10.114 5.753 1.00 37.39 ? 120 PRO B C 1 ATOM 1543 O O . PRO B 2 121 ? 35.380 -10.171 5.124 1.00 38.63 ? 120 PRO B O 1 ATOM 1544 C CB . PRO B 2 121 ? 36.436 -12.244 7.086 1.00 37.65 ? 120 PRO B CB 1 ATOM 1545 C CG . PRO B 2 121 ? 34.977 -12.542 7.125 1.00 37.27 ? 120 PRO B CG 1 ATOM 1546 C CD . PRO B 2 121 ? 34.443 -11.542 8.110 1.00 37.30 ? 120 PRO B CD 1 ATOM 1547 N N . PRO B 2 122 ? 37.555 -9.542 5.257 1.00 37.51 ? 121 PRO B N 1 ATOM 1548 C CA . PRO B 2 122 ? 37.562 -8.949 3.925 1.00 36.50 ? 121 PRO B CA 1 ATOM 1549 C C . PRO B 2 122 ? 37.728 -9.991 2.831 1.00 38.10 ? 121 PRO B C 1 ATOM 1550 O O . PRO B 2 122 ? 38.241 -11.087 3.085 1.00 39.20 ? 121 PRO B O 1 ATOM 1551 C CB . PRO B 2 122 ? 38.789 -8.051 3.966 1.00 36.43 ? 121 PRO B CB 1 ATOM 1552 C CG . PRO B 2 122 ? 39.740 -8.800 4.825 1.00 36.98 ? 121 PRO B CG 1 ATOM 1553 C CD . PRO B 2 122 ? 38.891 -9.460 5.882 1.00 37.60 ? 121 PRO B CD 1 ATOM 1554 N N . ALA B 2 123 ? 37.323 -9.632 1.617 1.00 38.64 ? 122 ALA B N 1 ATOM 1555 C CA . ALA B 2 123 ? 37.434 -10.523 0.467 1.00 38.44 ? 122 ALA B CA 1 ATOM 1556 C C . ALA B 2 123 ? 37.412 -9.737 -0.822 1.00 39.01 ? 122 ALA B C 1 ATOM 1557 O O . ALA B 2 123 ? 36.958 -8.599 -0.854 1.00 39.37 ? 122 ALA B O 1 ATOM 1558 C CB . ALA B 2 123 ? 36.296 -11.532 0.475 1.00 38.75 ? 122 ALA B CB 1 ATOM 1559 N N . ILE B 2 124 ? 37.907 -10.365 -1.884 1.00 40.48 ? 123 ILE B N 1 ATOM 1560 C CA . ILE B 2 124 ? 37.815 -9.824 -3.231 1.00 40.70 ? 123 ILE B CA 1 ATOM 1561 C C . ILE B 2 124 ? 36.864 -10.730 -4.005 1.00 42.17 ? 123 ILE B C 1 ATOM 1562 O O . ILE B 2 124 ? 37.137 -11.914 -4.170 1.00 43.35 ? 123 ILE B O 1 ATOM 1563 C CB . ILE B 2 124 ? 39.188 -9.797 -3.912 1.00 40.30 ? 123 ILE B CB 1 ATOM 1564 C CG1 . ILE B 2 124 ? 40.152 -8.907 -3.132 1.00 41.48 ? 123 ILE B CG1 1 ATOM 1565 C CG2 . ILE B 2 124 ? 39.073 -9.289 -5.338 1.00 40.72 ? 123 ILE B CG2 1 ATOM 1566 C CD1 . ILE B 2 124 ? 41.607 -9.240 -3.389 1.00 43.35 ? 123 ILE B CD1 1 ATOM 1567 N N . PHE B 2 125 ? 35.740 -10.176 -4.449 1.00 44.66 ? 124 PHE B N 1 ATOM 1568 C CA . PHE B 2 125 ? 34.777 -10.909 -5.262 1.00 46.58 ? 124 PHE B CA 1 ATOM 1569 C C . PHE B 2 125 ? 34.805 -10.411 -6.701 1.00 44.56 ? 124 PHE B C 1 ATOM 1570 O O . PHE B 2 125 ? 35.050 -9.238 -6.941 1.00 43.54 ? 124 PHE B O 1 ATOM 1571 C CB . PHE B 2 125 ? 33.371 -10.754 -4.690 1.00 50.42 ? 124 PHE B CB 1 ATOM 1572 C CG . PHE B 2 125 ? 32.374 -11.690 -5.307 1.00 54.48 ? 124 PHE B CG 1 ATOM 1573 C CD1 . PHE B 2 125 ? 32.373 -13.037 -4.963 1.00 56.14 ? 124 PHE B CD1 1 ATOM 1574 C CD2 . PHE B 2 125 ? 31.460 -11.240 -6.257 1.00 56.92 ? 124 PHE B CD2 1 ATOM 1575 C CE1 . PHE B 2 125 ? 31.468 -13.916 -5.537 1.00 58.26 ? 124 PHE B CE1 1 ATOM 1576 C CE2 . PHE B 2 125 ? 30.550 -12.117 -6.840 1.00 58.00 ? 124 PHE B CE2 1 ATOM 1577 C CZ . PHE B 2 125 ? 30.555 -13.453 -6.479 1.00 59.35 ? 124 PHE B CZ 1 ATOM 1578 N N . LYS B 2 126 ? 34.548 -11.315 -7.643 1.00 45.48 ? 125 LYS B N 1 ATOM 1579 C CA . LYS B 2 126 ? 34.452 -10.990 -9.065 1.00 48.16 ? 125 LYS B CA 1 ATOM 1580 C C . LYS B 2 126 ? 33.053 -11.336 -9.553 1.00 46.94 ? 125 LYS B C 1 ATOM 1581 O O . LYS B 2 126 ? 32.771 -12.496 -9.813 1.00 48.44 ? 125 LYS B O 1 ATOM 1582 C CB . LYS B 2 126 ? 35.483 -11.787 -9.880 1.00 50.29 ? 125 LYS B CB 1 ATOM 1583 C CG . LYS B 2 126 ? 36.945 -11.444 -9.613 1.00 52.72 ? 125 LYS B CG 1 ATOM 1584 C CD . LYS B 2 126 ? 37.846 -11.975 -10.731 1.00 55.80 ? 125 LYS B CD 1 ATOM 1585 C CE . LYS B 2 126 ? 39.284 -12.250 -10.287 1.00 57.60 ? 125 LYS B CE 1 ATOM 1586 N NZ . LYS B 2 126 ? 40.109 -11.024 -10.091 1.00 58.60 ? 125 LYS B NZ 1 ATOM 1587 N N . SER B 2 127 ? 32.182 -10.336 -9.663 1.00 48.67 ? 126 SER B N 1 ATOM 1588 C CA . SER B 2 127 ? 30.821 -10.540 -10.188 1.00 52.03 ? 126 SER B CA 1 ATOM 1589 C C . SER B 2 127 ? 30.824 -10.683 -11.701 1.00 54.70 ? 126 SER B C 1 ATOM 1590 O O . SER B 2 127 ? 31.729 -10.194 -12.374 1.00 53.44 ? 126 SER B O 1 ATOM 1591 C CB . SER B 2 127 ? 29.879 -9.383 -9.813 1.00 52.71 ? 126 SER B CB 1 ATOM 1592 O OG . SER B 2 127 ? 29.284 -9.584 -8.543 1.00 54.14 ? 126 SER B OG 1 ATOM 1593 N N . TYR B 2 128 ? 29.811 -11.379 -12.216 1.00 58.77 ? 127 TYR B N 1 ATOM 1594 C CA . TYR B 2 128 ? 29.418 -11.273 -13.619 1.00 62.52 ? 127 TYR B CA 1 ATOM 1595 C C . TYR B 2 128 ? 28.190 -10.368 -13.650 1.00 58.89 ? 127 TYR B C 1 ATOM 1596 O O . TYR B 2 128 ? 27.298 -10.503 -12.810 1.00 59.35 ? 127 TYR B O 1 ATOM 1597 C CB . TYR B 2 128 ? 29.098 -12.646 -14.208 1.00 68.30 ? 127 TYR B CB 1 ATOM 1598 C CG . TYR B 2 128 ? 28.692 -12.605 -15.668 1.00 76.02 ? 127 TYR B CG 1 ATOM 1599 C CD1 . TYR B 2 128 ? 29.655 -12.595 -16.683 1.00 79.84 ? 127 TYR B CD1 1 ATOM 1600 C CD2 . TYR B 2 128 ? 27.342 -12.575 -16.042 1.00 80.15 ? 127 TYR B CD2 1 ATOM 1601 C CE1 . TYR B 2 128 ? 29.287 -12.557 -18.027 1.00 81.41 ? 127 TYR B CE1 1 ATOM 1602 C CE2 . TYR B 2 128 ? 26.966 -12.535 -17.382 1.00 82.11 ? 127 TYR B CE2 1 ATOM 1603 C CZ . TYR B 2 128 ? 27.939 -12.528 -18.371 1.00 83.02 ? 127 TYR B CZ 1 ATOM 1604 O OH . TYR B 2 128 ? 27.560 -12.492 -19.697 1.00 84.31 ? 127 TYR B OH 1 ATOM 1605 N N . CYS B 2 129 ? 28.151 -9.445 -14.607 1.00 55.99 ? 128 CYS B N 1 ATOM 1606 C CA . CYS B 2 129 ? 27.102 -8.426 -14.669 1.00 55.81 ? 128 CYS B CA 1 ATOM 1607 C C . CYS B 2 129 ? 26.263 -8.563 -15.935 1.00 54.46 ? 128 CYS B C 1 ATOM 1608 O O . CYS B 2 129 ? 26.799 -8.816 -17.009 1.00 53.75 ? 128 CYS B O 1 ATOM 1609 C CB . CYS B 2 129 ? 27.726 -7.032 -14.594 1.00 55.67 ? 128 CYS B CB 1 ATOM 1610 S SG . CYS B 2 129 ? 28.812 -6.814 -13.161 1.00 56.08 ? 128 CYS B SG 1 ATOM 1611 N N . GLU B 2 130 ? 24.949 -8.409 -15.795 1.00 54.78 ? 129 GLU B N 1 ATOM 1612 C CA . GLU B 2 130 ? 24.034 -8.424 -16.933 1.00 56.47 ? 129 GLU B CA 1 ATOM 1613 C C . GLU B 2 130 ? 23.802 -6.991 -17.363 1.00 53.09 ? 129 GLU B C 1 ATOM 1614 O O . GLU B 2 130 ? 23.585 -6.128 -16.522 1.00 50.46 ? 129 GLU B O 1 ATOM 1615 C CB . GLU B 2 130 ? 22.688 -9.048 -16.550 1.00 61.88 ? 129 GLU B CB 1 ATOM 1616 C CG . GLU B 2 130 ? 22.754 -10.488 -16.045 1.00 67.29 ? 129 GLU B CG 1 ATOM 1617 C CD . GLU B 2 130 ? 23.222 -11.500 -17.089 1.00 71.81 ? 129 GLU B CD 1 ATOM 1618 O OE1 . GLU B 2 130 ? 23.124 -11.231 -18.311 1.00 75.76 ? 129 GLU B OE1 1 ATOM 1619 O OE2 . GLU B 2 130 ? 23.683 -12.587 -16.678 1.00 74.84 ? 129 GLU B OE2 1 ATOM 1620 N N . ILE B 2 131 ? 23.841 -6.740 -18.665 1.00 52.99 ? 130 ILE B N 1 ATOM 1621 C CA . ILE B 2 131 ? 23.519 -5.421 -19.203 1.00 55.70 ? 130 ILE B CA 1 ATOM 1622 C C . ILE B 2 131 ? 22.001 -5.235 -19.138 1.00 56.90 ? 130 ILE B C 1 ATOM 1623 O O . ILE B 2 131 ? 21.257 -6.081 -19.625 1.00 56.42 ? 130 ILE B O 1 ATOM 1624 C CB . ILE B 2 131 ? 24.012 -5.258 -20.665 1.00 56.69 ? 130 ILE B CB 1 ATOM 1625 C CG1 . ILE B 2 131 ? 25.546 -5.341 -20.743 1.00 56.98 ? 130 ILE B CG1 1 ATOM 1626 C CG2 . ILE B 2 131 ? 23.520 -3.947 -21.277 1.00 56.28 ? 130 ILE B CG2 1 ATOM 1627 C CD1 . ILE B 2 131 ? 26.277 -4.106 -20.257 1.00 57.61 ? 130 ILE B CD1 1 ATOM 1628 N N . ILE B 2 132 ? 21.558 -4.138 -18.527 1.00 60.18 ? 131 ILE B N 1 ATOM 1629 C CA . ILE B 2 132 ? 20.145 -3.788 -18.465 1.00 63.54 ? 131 ILE B CA 1 ATOM 1630 C C . ILE B 2 132 ? 19.791 -3.059 -19.751 1.00 71.25 ? 131 ILE B C 1 ATOM 1631 O O . ILE B 2 132 ? 20.391 -2.027 -20.073 1.00 69.84 ? 131 ILE B O 1 ATOM 1632 C CB . ILE B 2 132 ? 19.816 -2.891 -17.254 1.00 62.82 ? 131 ILE B CB 1 ATOM 1633 C CG1 . ILE B 2 132 ? 20.113 -3.637 -15.947 1.00 61.78 ? 131 ILE B CG1 1 ATOM 1634 C CG2 . ILE B 2 132 ? 18.356 -2.430 -17.299 1.00 63.38 ? 131 ILE B CG2 1 ATOM 1635 C CD1 . ILE B 2 132 ? 19.949 -2.791 -14.700 1.00 62.37 ? 131 ILE B CD1 1 ATOM 1636 N N . VAL B 2 133 ? 18.796 -3.595 -20.458 1.00 84.73 ? 132 VAL B N 1 ATOM 1637 C CA . VAL B 2 133 ? 18.418 -3.131 -21.802 1.00 93.35 ? 132 VAL B CA 1 ATOM 1638 C C . VAL B 2 133 ? 17.099 -2.329 -21.826 1.00 104.05 ? 132 VAL B C 1 ATOM 1639 O O . VAL B 2 133 ? 16.542 -2.099 -22.903 1.00 109.68 ? 132 VAL B O 1 ATOM 1640 C CB . VAL B 2 133 ? 18.365 -4.314 -22.817 1.00 90.38 ? 132 VAL B CB 1 ATOM 1641 C CG1 . VAL B 2 133 ? 19.732 -4.974 -22.935 1.00 90.11 ? 132 VAL B CG1 1 ATOM 1642 C CG2 . VAL B 2 133 ? 17.308 -5.356 -22.447 1.00 89.82 ? 132 VAL B CG2 1 ATOM 1643 N N . THR B 2 134 ? 16.617 -1.892 -20.657 1.00 112.55 ? 133 THR B N 1 ATOM 1644 C CA . THR B 2 134 ? 15.337 -1.173 -20.551 1.00 119.18 ? 133 THR B CA 1 ATOM 1645 C C . THR B 2 134 ? 15.444 0.203 -21.210 1.00 127.29 ? 133 THR B C 1 ATOM 1646 O O . THR B 2 134 ? 14.670 0.528 -22.111 1.00 132.01 ? 133 THR B O 1 ATOM 1647 C CB . THR B 2 134 ? 14.877 -1.014 -19.079 1.00 117.26 ? 133 THR B CB 1 ATOM 1648 O OG1 . THR B 2 134 ? 14.977 -2.271 -18.398 1.00 117.96 ? 133 THR B OG1 1 ATOM 1649 C CG2 . THR B 2 134 ? 13.433 -0.524 -19.000 1.00 115.77 ? 133 THR B CG2 1 ATOM 1650 N N . HIS B 2 135 ? 16.412 0.993 -20.754 1.00 134.95 ? 134 HIS B N 1 ATOM 1651 C CA . HIS B 2 135 ? 16.721 2.300 -21.340 1.00 140.83 ? 134 HIS B CA 1 ATOM 1652 C C . HIS B 2 135 ? 18.192 2.599 -21.069 1.00 142.57 ? 134 HIS B C 1 ATOM 1653 O O . HIS B 2 135 ? 18.566 2.829 -19.915 1.00 142.99 ? 134 HIS B O 1 ATOM 1654 C CB . HIS B 2 135 ? 15.837 3.402 -20.728 1.00 143.68 ? 134 HIS B CB 1 ATOM 1655 C CG . HIS B 2 135 ? 14.525 3.599 -21.429 1.00 143.72 ? 134 HIS B CG 1 ATOM 1656 N ND1 . HIS B 2 135 ? 13.411 2.833 -21.158 1.00 143.91 ? 134 HIS B ND1 1 ATOM 1657 C CD2 . HIS B 2 135 ? 14.147 4.486 -22.380 1.00 144.36 ? 134 HIS B CD2 1 ATOM 1658 C CE1 . HIS B 2 135 ? 12.407 3.232 -21.919 1.00 142.12 ? 134 HIS B CE1 1 ATOM 1659 N NE2 . HIS B 2 135 ? 12.828 4.234 -22.670 1.00 143.06 ? 134 HIS B NE2 1 ATOM 1660 N N . PHE B 2 136 ? 19.024 2.574 -22.113 1.00 143.28 ? 135 PHE B N 1 ATOM 1661 C CA . PHE B 2 136 ? 20.462 2.827 -21.949 1.00 144.05 ? 135 PHE B CA 1 ATOM 1662 C C . PHE B 2 136 ? 21.111 3.743 -23.010 1.00 143.87 ? 135 PHE B C 1 ATOM 1663 O O . PHE B 2 136 ? 22.014 3.327 -23.745 1.00 145.86 ? 135 PHE B O 1 ATOM 1664 C CB . PHE B 2 136 ? 21.237 1.500 -21.738 1.00 144.87 ? 135 PHE B CB 1 ATOM 1665 C CG . PHE B 2 136 ? 21.221 0.556 -22.919 1.00 145.60 ? 135 PHE B CG 1 ATOM 1666 C CD1 . PHE B 2 136 ? 20.063 -0.134 -23.275 1.00 142.89 ? 135 PHE B CD1 1 ATOM 1667 C CD2 . PHE B 2 136 ? 22.388 0.319 -23.654 1.00 142.80 ? 135 PHE B CD2 1 ATOM 1668 C CE1 . PHE B 2 136 ? 20.060 -1.012 -24.353 1.00 139.90 ? 135 PHE B CE1 1 ATOM 1669 C CE2 . PHE B 2 136 ? 22.388 -0.556 -24.731 1.00 140.01 ? 135 PHE B CE2 1 ATOM 1670 C CZ . PHE B 2 136 ? 21.223 -1.224 -25.080 1.00 139.07 ? 135 PHE B CZ 1 ATOM 1671 N N . PRO B 2 137 ? 20.642 5.009 -23.089 1.00 138.15 ? 136 PRO B N 1 ATOM 1672 C CA . PRO B 2 137 ? 21.521 6.085 -23.566 1.00 131.40 ? 136 PRO B CA 1 ATOM 1673 C C . PRO B 2 137 ? 22.678 6.290 -22.576 1.00 126.58 ? 136 PRO B C 1 ATOM 1674 O O . PRO B 2 137 ? 23.838 6.395 -22.988 1.00 124.52 ? 136 PRO B O 1 ATOM 1675 C CB . PRO B 2 137 ? 20.598 7.310 -23.612 1.00 130.37 ? 136 PRO B CB 1 ATOM 1676 C CG . PRO B 2 137 ? 19.224 6.752 -23.737 1.00 130.96 ? 136 PRO B CG 1 ATOM 1677 C CD . PRO B 2 137 ? 19.237 5.451 -22.991 1.00 134.46 ? 136 PRO B CD 1 ATOM 1678 N N . PHE B 2 138 ? 22.338 6.351 -21.286 1.00 119.80 ? 137 PHE B N 1 ATOM 1679 C CA . PHE B 2 138 ? 23.298 6.206 -20.193 1.00 112.57 ? 137 PHE B CA 1 ATOM 1680 C C . PHE B 2 138 ? 23.331 4.723 -19.805 1.00 105.42 ? 137 PHE B C 1 ATOM 1681 O O . PHE B 2 138 ? 22.311 4.168 -19.391 1.00 100.47 ? 137 PHE B O 1 ATOM 1682 C CB . PHE B 2 138 ? 22.887 7.067 -18.995 1.00 109.29 ? 137 PHE B CB 1 ATOM 1683 N N . ASP B 2 139 ? 24.503 4.099 -19.932 1.00 97.79 ? 138 ASP B N 1 ATOM 1684 C CA . ASP B 2 139 ? 24.654 2.641 -19.782 1.00 89.29 ? 138 ASP B CA 1 ATOM 1685 C C . ASP B 2 139 ? 24.403 2.181 -18.350 1.00 82.26 ? 138 ASP B C 1 ATOM 1686 O O . ASP B 2 139 ? 24.680 2.918 -17.404 1.00 81.90 ? 138 ASP B O 1 ATOM 1687 C CB . ASP B 2 139 ? 26.054 2.197 -20.207 1.00 91.31 ? 138 ASP B CB 1 ATOM 1688 C CG . ASP B 2 139 ? 26.371 2.562 -21.641 1.00 93.79 ? 138 ASP B CG 1 ATOM 1689 O OD1 . ASP B 2 139 ? 25.611 2.144 -22.541 1.00 96.67 ? 138 ASP B OD1 1 ATOM 1690 O OD2 . ASP B 2 139 ? 27.375 3.273 -21.861 1.00 94.70 ? 138 ASP B OD2 1 ATOM 1691 N N . GLU B 2 140 ? 23.878 0.963 -18.211 1.00 73.38 ? 139 GLU B N 1 ATOM 1692 C CA . GLU B 2 140 ? 23.529 0.385 -16.909 1.00 67.16 ? 139 GLU B CA 1 ATOM 1693 C C . GLU B 2 140 ? 23.781 -1.111 -16.901 1.00 59.97 ? 139 GLU B C 1 ATOM 1694 O O . GLU B 2 140 ? 23.505 -1.791 -17.890 1.00 58.81 ? 139 GLU B O 1 ATOM 1695 C CB . GLU B 2 140 ? 22.056 0.626 -16.582 1.00 69.38 ? 139 GLU B CB 1 ATOM 1696 C CG . GLU B 2 140 ? 21.756 1.998 -16.005 1.00 73.39 ? 139 GLU B CG 1 ATOM 1697 C CD . GLU B 2 140 ? 20.292 2.187 -15.626 1.00 77.14 ? 139 GLU B CD 1 ATOM 1698 O OE1 . GLU B 2 140 ? 19.596 1.188 -15.325 1.00 79.38 ? 139 GLU B OE1 1 ATOM 1699 O OE2 . GLU B 2 140 ? 19.833 3.351 -15.621 1.00 79.99 ? 139 GLU B OE2 1 ATOM 1700 N N . GLN B 2 141 ? 24.287 -1.616 -15.781 1.00 52.79 ? 140 GLN B N 1 ATOM 1701 C CA . GLN B 2 141 ? 24.500 -3.039 -15.618 1.00 49.96 ? 140 GLN B CA 1 ATOM 1702 C C . GLN B 2 141 ? 24.233 -3.491 -14.193 1.00 45.88 ? 140 GLN B C 1 ATOM 1703 O O . GLN B 2 141 ? 24.436 -2.740 -13.251 1.00 43.71 ? 140 GLN B O 1 ATOM 1704 C CB . GLN B 2 141 ? 25.908 -3.431 -16.069 1.00 52.73 ? 140 GLN B CB 1 ATOM 1705 C CG . GLN B 2 141 ? 27.053 -2.725 -15.364 1.00 55.65 ? 140 GLN B CG 1 ATOM 1706 C CD . GLN B 2 141 ? 28.408 -3.130 -15.929 1.00 58.77 ? 140 GLN B CD 1 ATOM 1707 O OE1 . GLN B 2 141 ? 28.629 -3.070 -17.142 1.00 62.17 ? 140 GLN B OE1 1 ATOM 1708 N NE2 . GLN B 2 141 ? 29.323 -3.540 -15.053 1.00 59.34 ? 140 GLN B NE2 1 ATOM 1709 N N . ASN B 2 142 ? 23.783 -4.739 -14.070 1.00 44.51 ? 141 ASN B N 1 ATOM 1710 C CA . ASN B 2 142 ? 23.343 -5.338 -12.818 1.00 42.79 ? 141 ASN B CA 1 ATOM 1711 C C . ASN B 2 142 ? 24.321 -6.451 -12.445 1.00 43.64 ? 141 ASN B C 1 ATOM 1712 O O . ASN B 2 142 ? 24.462 -7.422 -13.188 1.00 43.99 ? 141 ASN B O 1 ATOM 1713 C CB . ASN B 2 142 ? 21.934 -5.904 -13.017 1.00 42.20 ? 141 ASN B CB 1 ATOM 1714 C CG . ASN B 2 142 ? 21.297 -6.401 -11.733 1.00 42.28 ? 141 ASN B CG 1 ATOM 1715 O OD1 . ASN B 2 142 ? 21.856 -6.258 -10.641 1.00 43.50 ? 141 ASN B OD1 1 ATOM 1716 N ND2 . ASN B 2 142 ? 20.106 -6.988 -11.862 1.00 40.78 ? 141 ASN B ND2 1 ATOM 1717 N N . CYS B 2 143 ? 24.986 -6.291 -11.299 1.00 45.29 ? 142 CYS B N 1 ATOM 1718 C CA . CYS B 2 143 ? 25.996 -7.230 -10.790 1.00 46.62 ? 142 CYS B CA 1 ATOM 1719 C C . CYS B 2 143 ? 25.513 -7.810 -9.474 1.00 44.90 ? 142 CYS B C 1 ATOM 1720 O O . CYS B 2 143 ? 25.065 -7.058 -8.617 1.00 43.26 ? 142 CYS B O 1 ATOM 1721 C CB . CYS B 2 143 ? 27.313 -6.501 -10.552 1.00 49.57 ? 142 CYS B CB 1 ATOM 1722 S SG . CYS B 2 143 ? 27.826 -5.490 -11.957 1.00 56.73 ? 142 CYS B SG 1 ATOM 1723 N N . SER B 2 144 ? 25.600 -9.134 -9.310 1.00 45.31 ? 143 SER B N 1 ATOM 1724 C CA . SER B 2 144 ? 25.090 -9.788 -8.098 1.00 46.02 ? 143 SER B CA 1 ATOM 1725 C C . SER B 2 144 ? 26.075 -10.777 -7.476 1.00 45.49 ? 143 SER B C 1 ATOM 1726 O O . SER B 2 144 ? 26.919 -11.342 -8.172 1.00 45.89 ? 143 SER B O 1 ATOM 1727 C CB . SER B 2 144 ? 23.743 -10.461 -8.374 1.00 45.85 ? 143 SER B CB 1 ATOM 1728 O OG . SER B 2 144 ? 23.908 -11.757 -8.903 1.00 47.42 ? 143 SER B OG 1 ATOM 1729 N N . MET B 2 145 ? 25.946 -10.958 -6.159 1.00 45.64 ? 144 MET B N 1 ATOM 1730 C CA . MET B 2 145 ? 26.783 -11.870 -5.373 1.00 46.90 ? 144 MET B CA 1 ATOM 1731 C C . MET B 2 145 ? 25.889 -12.697 -4.473 1.00 46.96 ? 144 MET B C 1 ATOM 1732 O O . MET B 2 145 ? 25.085 -12.133 -3.733 1.00 45.20 ? 144 MET B O 1 ATOM 1733 C CB . MET B 2 145 ? 27.752 -11.110 -4.470 1.00 47.99 ? 144 MET B CB 1 ATOM 1734 C CG . MET B 2 145 ? 28.305 -9.820 -5.032 1.00 50.36 ? 144 MET B CG 1 ATOM 1735 S SD . MET B 2 145 ? 29.270 -8.999 -3.758 1.00 51.51 ? 144 MET B SD 1 ATOM 1736 C CE . MET B 2 145 ? 29.962 -7.669 -4.729 1.00 51.77 ? 144 MET B CE 1 ATOM 1737 N N . LYS B 2 146 ? 26.049 -14.020 -4.519 1.00 48.46 ? 145 LYS B N 1 ATOM 1738 C CA . LYS B 2 146 ? 25.315 -14.925 -3.638 1.00 49.59 ? 145 LYS B CA 1 ATOM 1739 C C . LYS B 2 146 ? 26.154 -15.297 -2.418 1.00 48.36 ? 145 LYS B C 1 ATOM 1740 O O . LYS B 2 146 ? 27.361 -15.489 -2.524 1.00 47.91 ? 145 LYS B O 1 ATOM 1741 C CB . LYS B 2 146 ? 24.885 -16.179 -4.398 1.00 52.10 ? 145 LYS B CB 1 ATOM 1742 C CG . LYS B 2 146 ? 24.018 -15.855 -5.604 1.00 55.63 ? 145 LYS B CG 1 ATOM 1743 C CD . LYS B 2 146 ? 23.099 -16.995 -6.001 1.00 56.93 ? 145 LYS B CD 1 ATOM 1744 C CE . LYS B 2 146 ? 22.106 -16.542 -7.063 1.00 60.12 ? 145 LYS B CE 1 ATOM 1745 N NZ . LYS B 2 146 ? 20.730 -17.024 -6.751 1.00 65.11 ? 145 LYS B NZ 1 ATOM 1746 N N . LEU B 2 147 ? 25.491 -15.376 -1.267 1.00 47.27 ? 146 LEU B N 1 ATOM 1747 C CA . LEU B 2 147 ? 26.086 -15.810 -0.015 1.00 46.43 ? 146 LEU B CA 1 ATOM 1748 C C . LEU B 2 147 ? 25.316 -16.995 0.531 1.00 46.03 ? 146 LEU B C 1 ATOM 1749 O O . LEU B 2 147 ? 24.085 -16.994 0.506 1.00 44.22 ? 146 LEU B O 1 ATOM 1750 C CB . LEU B 2 147 ? 25.999 -14.699 1.023 1.00 47.59 ? 146 LEU B CB 1 ATOM 1751 C CG . LEU B 2 147 ? 26.887 -13.482 0.841 1.00 48.03 ? 146 LEU B CG 1 ATOM 1752 C CD1 . LEU B 2 147 ? 26.597 -12.530 1.977 1.00 47.23 ? 146 LEU B CD1 1 ATOM 1753 C CD2 . LEU B 2 147 ? 28.344 -13.887 0.858 1.00 50.23 ? 146 LEU B CD2 1 ATOM 1754 N N . GLY B 2 148 ? 26.036 -17.981 1.059 1.00 45.19 ? 147 GLY B N 1 ATOM 1755 C CA . GLY B 2 148 ? 25.403 -19.113 1.731 1.00 43.21 ? 147 GLY B CA 1 ATOM 1756 C C . GLY B 2 148 ? 26.413 -19.997 2.420 1.00 41.05 ? 147 GLY B C 1 ATOM 1757 O O . GLY B 2 148 ? 27.587 -19.970 2.072 1.00 41.39 ? 147 GLY B O 1 ATOM 1758 N N . THR B 2 149 ? 25.949 -20.781 3.392 1.00 40.52 ? 148 THR B N 1 ATOM 1759 C CA . THR B 2 149 ? 26.790 -21.770 4.073 1.00 40.36 ? 148 THR B CA 1 ATOM 1760 C C . THR B 2 149 ? 27.191 -22.878 3.098 1.00 41.07 ? 148 THR B C 1 ATOM 1761 O O . THR B 2 149 ? 26.342 -23.414 2.383 1.00 39.56 ? 148 THR B O 1 ATOM 1762 C CB . THR B 2 149 ? 26.080 -22.393 5.294 1.00 40.21 ? 148 THR B CB 1 ATOM 1763 O OG1 . THR B 2 149 ? 24.791 -22.885 4.913 1.00 40.79 ? 148 THR B OG1 1 ATOM 1764 C CG2 . THR B 2 149 ? 25.901 -21.368 6.409 1.00 40.56 ? 148 THR B CG2 1 ATOM 1765 N N . ARG B 2 150 ? 28.486 -23.193 3.071 1.00 43.85 ? 149 ARG B N 1 ATOM 1766 C CA . ARG B 2 150 ? 29.068 -24.179 2.144 1.00 45.60 ? 149 ARG B CA 1 ATOM 1767 C C . ARG B 2 150 ? 28.501 -25.598 2.308 1.00 45.00 ? 149 ARG B C 1 ATOM 1768 O O . ARG B 2 150 ? 28.266 -26.289 1.310 1.00 46.83 ? 149 ARG B O 1 ATOM 1769 C CB . ARG B 2 150 ? 30.595 -24.230 2.326 1.00 47.68 ? 149 ARG B CB 1 ATOM 1770 C CG . ARG B 2 150 ? 31.345 -25.110 1.327 1.00 50.24 ? 149 ARG B CG 1 ATOM 1771 C CD . ARG B 2 150 ? 32.736 -25.468 1.830 1.00 53.07 ? 149 ARG B CD 1 ATOM 1772 N NE . ARG B 2 150 ? 33.659 -24.333 1.766 1.00 55.37 ? 149 ARG B NE 1 ATOM 1773 C CZ . ARG B 2 150 ? 34.240 -23.876 0.652 1.00 57.89 ? 149 ARG B CZ 1 ATOM 1774 N NH1 . ARG B 2 150 ? 33.999 -24.432 -0.539 1.00 59.56 ? 149 ARG B NH1 1 ATOM 1775 N NH2 . ARG B 2 150 ? 35.068 -22.834 0.724 1.00 59.37 ? 149 ARG B NH2 1 ATOM 1776 N N . THR B 2 151 ? 28.287 -26.020 3.552 1.00 42.11 ? 150 THR B N 1 ATOM 1777 C CA . THR B 2 151 ? 27.921 -27.402 3.857 1.00 42.59 ? 150 THR B CA 1 ATOM 1778 C C . THR B 2 151 ? 26.641 -27.550 4.674 1.00 42.66 ? 150 THR B C 1 ATOM 1779 O O . THR B 2 151 ? 25.796 -28.398 4.344 1.00 42.81 ? 150 THR B O 1 ATOM 1780 C CB . THR B 2 151 ? 29.074 -28.090 4.592 1.00 43.35 ? 150 THR B CB 1 ATOM 1781 O OG1 . THR B 2 151 ? 30.231 -28.056 3.748 1.00 46.01 ? 150 THR B OG1 1 ATOM 1782 C CG2 . THR B 2 151 ? 28.736 -29.538 4.932 1.00 43.66 ? 150 THR B CG2 1 ATOM 1783 N N . TYR B 2 152 ? 26.516 -26.762 5.745 1.00 40.79 ? 151 TYR B N 1 ATOM 1784 C CA . TYR B 2 152 ? 25.300 -26.753 6.559 1.00 40.20 ? 151 TYR B CA 1 ATOM 1785 C C . TYR B 2 152 ? 24.091 -26.360 5.714 1.00 40.45 ? 151 TYR B C 1 ATOM 1786 O O . TYR B 2 152 ? 24.212 -25.604 4.750 1.00 38.37 ? 151 TYR B O 1 ATOM 1787 C CB . TYR B 2 152 ? 25.421 -25.799 7.753 1.00 38.84 ? 151 TYR B CB 1 ATOM 1788 C CG . TYR B 2 152 ? 26.425 -26.241 8.791 1.00 38.96 ? 151 TYR B CG 1 ATOM 1789 C CD1 . TYR B 2 152 ? 26.246 -27.428 9.501 1.00 39.07 ? 151 TYR B CD1 1 ATOM 1790 C CD2 . TYR B 2 152 ? 27.555 -25.470 9.074 1.00 39.30 ? 151 TYR B CD2 1 ATOM 1791 C CE1 . TYR B 2 152 ? 27.162 -27.841 10.459 1.00 38.70 ? 151 TYR B CE1 1 ATOM 1792 C CE2 . TYR B 2 152 ? 28.478 -25.876 10.028 1.00 39.54 ? 151 TYR B CE2 1 ATOM 1793 C CZ . TYR B 2 152 ? 28.276 -27.062 10.716 1.00 39.33 ? 151 TYR B CZ 1 ATOM 1794 O OH . TYR B 2 152 ? 29.194 -27.465 11.656 1.00 39.56 ? 151 TYR B OH 1 ATOM 1795 N N . ASP B 2 153 ? 22.940 -26.911 6.084 1.00 41.96 ? 152 ASP B N 1 ATOM 1796 C CA . ASP B 2 153 ? 21.673 -26.639 5.421 1.00 43.38 ? 152 ASP B CA 1 ATOM 1797 C C . ASP B 2 153 ? 20.821 -25.792 6.361 1.00 42.33 ? 152 ASP B C 1 ATOM 1798 O O . ASP B 2 153 ? 21.226 -25.528 7.491 1.00 41.43 ? 152 ASP B O 1 ATOM 1799 C CB . ASP B 2 153 ? 20.972 -27.947 4.987 1.00 46.62 ? 152 ASP B CB 1 ATOM 1800 C CG . ASP B 2 153 ? 20.630 -28.887 6.162 1.00 50.75 ? 152 ASP B CG 1 ATOM 1801 O OD1 . ASP B 2 153 ? 19.882 -28.489 7.086 1.00 53.21 ? 152 ASP B OD1 1 ATOM 1802 O OD2 . ASP B 2 153 ? 21.079 -30.055 6.133 1.00 53.34 ? 152 ASP B OD2 1 ATOM 1803 N N . GLY B 2 154 ? 19.643 -25.383 5.888 1.00 43.37 ? 153 GLY B N 1 ATOM 1804 C CA . GLY B 2 154 ? 18.746 -24.491 6.621 1.00 42.39 ? 153 GLY B CA 1 ATOM 1805 C C . GLY B 2 154 ? 18.183 -24.993 7.938 1.00 43.13 ? 153 GLY B C 1 ATOM 1806 O O . GLY B 2 154 ? 17.680 -24.194 8.722 1.00 46.17 ? 153 GLY B O 1 ATOM 1807 N N . SER B 2 155 ? 18.239 -26.301 8.187 1.00 44.35 ? 154 SER B N 1 ATOM 1808 C CA . SER B 2 155 ? 17.826 -26.865 9.482 1.00 46.25 ? 154 SER B CA 1 ATOM 1809 C C . SER B 2 155 ? 18.984 -27.001 10.500 1.00 46.67 ? 154 SER B C 1 ATOM 1810 O O . SER B 2 155 ? 18.782 -27.547 11.598 1.00 47.69 ? 154 SER B O 1 ATOM 1811 C CB . SER B 2 155 ? 17.157 -28.222 9.272 1.00 45.86 ? 154 SER B CB 1 ATOM 1812 O OG . SER B 2 155 ? 18.115 -29.183 8.857 1.00 48.84 ? 154 SER B OG 1 ATOM 1813 N N . ALA B 2 156 ? 20.182 -26.537 10.131 1.00 44.35 ? 155 ALA B N 1 ATOM 1814 C CA . ALA B 2 156 ? 21.329 -26.472 11.048 1.00 43.42 ? 155 ALA B CA 1 ATOM 1815 C C . ALA B 2 156 ? 21.801 -25.036 11.295 1.00 42.80 ? 155 ALA B C 1 ATOM 1816 O O . ALA B 2 156 ? 22.069 -24.653 12.442 1.00 40.29 ? 155 ALA B O 1 ATOM 1817 C CB . ALA B 2 156 ? 22.472 -27.308 10.500 1.00 43.03 ? 155 ALA B CB 1 ATOM 1818 N N . VAL B 2 157 ? 21.936 -24.266 10.211 1.00 41.93 ? 156 VAL B N 1 ATOM 1819 C CA . VAL B 2 157 ? 22.354 -22.870 10.271 1.00 41.51 ? 156 VAL B CA 1 ATOM 1820 C C . VAL B 2 157 ? 21.441 -22.041 9.377 1.00 40.89 ? 156 VAL B C 1 ATOM 1821 O O . VAL B 2 157 ? 21.404 -22.246 8.159 1.00 41.30 ? 156 VAL B O 1 ATOM 1822 C CB . VAL B 2 157 ? 23.821 -22.690 9.814 1.00 43.12 ? 156 VAL B CB 1 ATOM 1823 C CG1 . VAL B 2 157 ? 24.220 -21.219 9.830 1.00 44.09 ? 156 VAL B CG1 1 ATOM 1824 C CG2 . VAL B 2 157 ? 24.770 -23.505 10.691 1.00 43.43 ? 156 VAL B CG2 1 ATOM 1825 N N . ALA B 2 158 ? 20.705 -21.118 9.995 1.00 40.52 ? 157 ALA B N 1 ATOM 1826 C CA . ALA B 2 158 ? 19.886 -20.137 9.289 1.00 39.69 ? 157 ALA B CA 1 ATOM 1827 C C . ALA B 2 158 ? 20.644 -18.812 9.168 1.00 40.05 ? 157 ALA B C 1 ATOM 1828 O O . ALA B 2 158 ? 21.056 -18.248 10.185 1.00 42.34 ? 157 ALA B O 1 ATOM 1829 C CB . ALA B 2 158 ? 18.588 -19.922 10.038 1.00 39.44 ? 157 ALA B CB 1 ATOM 1830 N N . ILE B 2 159 ? 20.842 -18.322 7.941 1.00 39.11 ? 158 ILE B N 1 ATOM 1831 C CA . ILE B 2 159 ? 21.433 -16.987 7.738 1.00 38.46 ? 158 ILE B CA 1 ATOM 1832 C C . ILE B 2 159 ? 20.326 -15.953 7.609 1.00 38.04 ? 158 ILE B C 1 ATOM 1833 O O . ILE B 2 159 ? 19.355 -16.167 6.894 1.00 37.69 ? 158 ILE B O 1 ATOM 1834 C CB . ILE B 2 159 ? 22.419 -16.890 6.550 1.00 37.67 ? 158 ILE B CB 1 ATOM 1835 C CG1 . ILE B 2 159 ? 21.804 -17.345 5.222 1.00 38.27 ? 158 ILE B CG1 1 ATOM 1836 C CG2 . ILE B 2 159 ? 23.683 -17.678 6.855 1.00 37.89 ? 158 ILE B CG2 1 ATOM 1837 C CD1 . ILE B 2 159 ? 22.668 -17.028 4.013 1.00 38.79 ? 158 ILE B CD1 1 ATOM 1838 N N . ASN B 2 160 ? 20.480 -14.843 8.323 1.00 38.66 ? 159 ASN B N 1 ATOM 1839 C CA . ASN B 2 160 ? 19.475 -13.781 8.374 1.00 39.80 ? 159 ASN B CA 1 ATOM 1840 C C . ASN B 2 160 ? 20.134 -12.459 7.975 1.00 40.11 ? 159 ASN B C 1 ATOM 1841 O O . ASN B 2 160 ? 21.121 -12.053 8.603 1.00 39.75 ? 159 ASN B O 1 ATOM 1842 C CB . ASN B 2 160 ? 18.907 -13.657 9.793 1.00 40.59 ? 159 ASN B CB 1 ATOM 1843 C CG . ASN B 2 160 ? 18.427 -14.984 10.355 1.00 40.61 ? 159 ASN B CG 1 ATOM 1844 O OD1 . ASN B 2 160 ? 17.757 -15.746 9.664 1.00 42.45 ? 159 ASN B OD1 1 ATOM 1845 N ND2 . ASN B 2 160 ? 18.769 -15.264 11.616 1.00 39.35 ? 159 ASN B ND2 1 ATOM 1846 N N . PRO B 2 161 ? 19.603 -11.774 6.943 1.00 40.01 ? 160 PRO B N 1 ATOM 1847 C CA . PRO B 2 161 ? 20.226 -10.512 6.536 1.00 39.71 ? 160 PRO B CA 1 ATOM 1848 C C . PRO B 2 161 ? 20.035 -9.426 7.582 1.00 39.16 ? 160 PRO B C 1 ATOM 1849 O O . PRO B 2 161 ? 18.918 -9.243 8.030 1.00 40.42 ? 160 PRO B O 1 ATOM 1850 C CB . PRO B 2 161 ? 19.490 -10.154 5.244 1.00 39.44 ? 160 PRO B CB 1 ATOM 1851 C CG . PRO B 2 161 ? 18.176 -10.826 5.350 1.00 40.12 ? 160 PRO B CG 1 ATOM 1852 C CD . PRO B 2 161 ? 18.395 -12.073 6.153 1.00 40.46 ? 160 PRO B CD 1 ATOM 1853 N N . GLU B 2 162 ? 21.110 -8.740 7.976 1.00 41.15 ? 161 GLU B N 1 ATOM 1854 C CA . GLU B 2 162 ? 21.012 -7.607 8.918 1.00 45.15 ? 161 GLU B CA 1 ATOM 1855 C C . GLU B 2 162 ? 20.210 -6.400 8.391 1.00 44.66 ? 161 GLU B C 1 ATOM 1856 O O . GLU B 2 162 ? 19.605 -5.662 9.172 1.00 44.58 ? 161 GLU B O 1 ATOM 1857 C CB . GLU B 2 162 ? 22.398 -7.147 9.404 1.00 48.18 ? 161 GLU B CB 1 ATOM 1858 C CG . GLU B 2 162 ? 23.293 -6.469 8.371 1.00 52.47 ? 161 GLU B CG 1 ATOM 1859 C CD . GLU B 2 162 ? 24.603 -5.932 8.961 1.00 57.65 ? 161 GLU B CD 1 ATOM 1860 O OE1 . GLU B 2 162 ? 25.451 -5.459 8.159 1.00 62.85 ? 161 GLU B OE1 1 ATOM 1861 O OE2 . GLU B 2 162 ? 24.796 -5.966 10.208 1.00 55.05 ? 161 GLU B OE2 1 ATOM 1862 N N . SER B 2 163 ? 20.206 -6.210 7.077 1.00 44.76 ? 162 SER B N 1 ATOM 1863 C CA . SER B 2 163 ? 19.486 -5.108 6.445 1.00 46.04 ? 162 SER B CA 1 ATOM 1864 C C . SER B 2 163 ? 18.915 -5.553 5.103 1.00 46.69 ? 162 SER B C 1 ATOM 1865 O O . SER B 2 163 ? 19.286 -6.604 4.594 1.00 46.55 ? 162 SER B O 1 ATOM 1866 C CB . SER B 2 163 ? 20.441 -3.919 6.278 1.00 46.34 ? 162 SER B CB 1 ATOM 1867 O OG . SER B 2 163 ? 20.238 -3.230 5.060 1.00 47.41 ? 162 SER B OG 1 ATOM 1868 N N . ASP B 2 164 ? 18.010 -4.752 4.544 1.00 49.19 ? 163 ASP B N 1 ATOM 1869 C CA . ASP B 2 164 ? 17.490 -4.977 3.186 1.00 51.76 ? 163 ASP B CA 1 ATOM 1870 C C . ASP B 2 164 ? 18.509 -4.669 2.100 1.00 51.75 ? 163 ASP B C 1 ATOM 1871 O O . ASP B 2 164 ? 18.392 -5.177 0.986 1.00 50.25 ? 163 ASP B O 1 ATOM 1872 C CB . ASP B 2 164 ? 16.253 -4.116 2.919 1.00 56.29 ? 163 ASP B CB 1 ATOM 1873 C CG . ASP B 2 164 ? 14.976 -4.737 3.438 1.00 62.31 ? 163 ASP B CG 1 ATOM 1874 O OD1 . ASP B 2 164 ? 15.024 -5.561 4.382 1.00 68.22 ? 163 ASP B OD1 1 ATOM 1875 O OD2 . ASP B 2 164 ? 13.908 -4.393 2.884 1.00 68.16 ? 163 ASP B OD2 1 ATOM 1876 N N . GLN B 2 165 ? 19.479 -3.814 2.414 1.00 53.42 ? 164 GLN B N 1 ATOM 1877 C CA . GLN B 2 165 ? 20.478 -3.367 1.455 1.00 55.54 ? 164 GLN B CA 1 ATOM 1878 C C . GLN B 2 165 ? 21.877 -3.729 1.937 1.00 52.68 ? 164 GLN B C 1 ATOM 1879 O O . GLN B 2 165 ? 22.089 -3.893 3.145 1.00 50.55 ? 164 GLN B O 1 ATOM 1880 C CB . GLN B 2 165 ? 20.397 -1.848 1.293 1.00 60.23 ? 164 GLN B CB 1 ATOM 1881 C CG . GLN B 2 165 ? 19.031 -1.333 0.861 1.00 64.46 ? 164 GLN B CG 1 ATOM 1882 C CD . GLN B 2 165 ? 18.984 0.180 0.763 1.00 69.21 ? 164 GLN B CD 1 ATOM 1883 O OE1 . GLN B 2 165 ? 19.439 0.889 1.666 1.00 73.55 ? 164 GLN B OE1 1 ATOM 1884 N NE2 . GLN B 2 165 ? 18.418 0.686 -0.330 1.00 73.05 ? 164 GLN B NE2 1 ATOM 1885 N N . PRO B 2 166 ? 22.838 -3.848 0.997 1.00 50.22 ? 165 PRO B N 1 ATOM 1886 C CA . PRO B 2 166 ? 24.232 -3.959 1.413 1.00 48.33 ? 165 PRO B CA 1 ATOM 1887 C C . PRO B 2 166 ? 24.709 -2.660 2.043 1.00 46.64 ? 165 PRO B C 1 ATOM 1888 O O . PRO B 2 166 ? 24.279 -1.584 1.636 1.00 47.81 ? 165 PRO B O 1 ATOM 1889 C CB . PRO B 2 166 ? 24.977 -4.223 0.104 1.00 49.11 ? 165 PRO B CB 1 ATOM 1890 C CG . PRO B 2 166 ? 24.104 -3.651 -0.956 1.00 50.20 ? 165 PRO B CG 1 ATOM 1891 C CD . PRO B 2 166 ? 22.702 -3.875 -0.474 1.00 50.48 ? 165 PRO B CD 1 ATOM 1892 N N . ASP B 2 167 ? 25.581 -2.782 3.035 1.00 45.38 ? 166 ASP B N 1 ATOM 1893 C CA . ASP B 2 167 ? 26.142 -1.642 3.745 1.00 44.82 ? 166 ASP B CA 1 ATOM 1894 C C . ASP B 2 167 ? 27.086 -0.862 2.812 1.00 45.85 ? 166 ASP B C 1 ATOM 1895 O O . ASP B 2 167 ? 28.135 -1.372 2.406 1.00 46.00 ? 166 ASP B O 1 ATOM 1896 C CB . ASP B 2 167 ? 26.880 -2.144 4.995 1.00 44.12 ? 166 ASP B CB 1 ATOM 1897 C CG . ASP B 2 167 ? 27.400 -1.026 5.885 1.00 44.86 ? 166 ASP B CG 1 ATOM 1898 O OD1 . ASP B 2 167 ? 27.223 0.166 5.558 1.00 44.16 ? 166 ASP B OD1 1 ATOM 1899 O OD2 . ASP B 2 167 ? 28.000 -1.354 6.934 1.00 46.26 ? 166 ASP B OD2 1 ATOM 1900 N N . LEU B 2 168 ? 26.692 0.368 2.474 1.00 45.85 ? 167 LEU B N 1 ATOM 1901 C CA . LEU B 2 168 ? 27.515 1.277 1.670 1.00 44.37 ? 167 LEU B CA 1 ATOM 1902 C C . LEU B 2 168 ? 28.129 2.418 2.496 1.00 42.19 ? 167 LEU B C 1 ATOM 1903 O O . LEU B 2 168 ? 28.514 3.437 1.933 1.00 41.86 ? 167 LEU B O 1 ATOM 1904 C CB . LEU B 2 168 ? 26.674 1.857 0.523 1.00 45.19 ? 167 LEU B CB 1 ATOM 1905 C CG . LEU B 2 168 ? 26.010 0.852 -0.425 1.00 47.20 ? 167 LEU B CG 1 ATOM 1906 C CD1 . LEU B 2 168 ? 25.218 1.574 -1.502 1.00 48.07 ? 167 LEU B CD1 1 ATOM 1907 C CD2 . LEU B 2 168 ? 27.038 -0.064 -1.068 1.00 48.45 ? 167 LEU B CD2 1 ATOM 1908 N N . SER B 2 169 ? 28.261 2.240 3.812 1.00 42.39 ? 168 SER B N 1 ATOM 1909 C CA . SER B 2 169 ? 28.710 3.329 4.689 1.00 42.92 ? 168 SER B CA 1 ATOM 1910 C C . SER B 2 169 ? 30.217 3.575 4.613 1.00 42.73 ? 168 SER B C 1 ATOM 1911 O O . SER B 2 169 ? 30.653 4.706 4.810 1.00 46.71 ? 168 SER B O 1 ATOM 1912 C CB . SER B 2 169 ? 28.246 3.128 6.139 1.00 42.81 ? 168 SER B CB 1 ATOM 1913 O OG . SER B 2 169 ? 28.982 2.120 6.798 1.00 45.92 ? 168 SER B OG 1 ATOM 1914 N N . ASN B 2 170 ? 31.002 2.541 4.311 1.00 42.57 ? 169 ASN B N 1 ATOM 1915 C CA . ASN B 2 170 ? 32.439 2.711 4.019 1.00 43.52 ? 169 ASN B CA 1 ATOM 1916 C C . ASN B 2 170 ? 32.763 2.507 2.540 1.00 42.55 ? 169 ASN B C 1 ATOM 1917 O O . ASN B 2 170 ? 33.906 2.195 2.194 1.00 41.16 ? 169 ASN B O 1 ATOM 1918 C CB . ASN B 2 170 ? 33.278 1.763 4.872 1.00 44.72 ? 169 ASN B CB 1 ATOM 1919 C CG . ASN B 2 170 ? 32.907 1.828 6.331 1.00 46.05 ? 169 ASN B CG 1 ATOM 1920 O OD1 . ASN B 2 170 ? 32.555 2.889 6.846 1.00 48.02 ? 169 ASN B OD1 1 ATOM 1921 N ND2 . ASN B 2 170 ? 32.963 0.690 7.003 1.00 47.23 ? 169 ASN B ND2 1 ATOM 1922 N N . PHE B 2 171 ? 31.770 2.724 1.674 1.00 42.63 ? 170 PHE B N 1 ATOM 1923 C CA . PHE B 2 171 ? 31.943 2.578 0.237 1.00 42.32 ? 170 PHE B CA 1 ATOM 1924 C C . PHE B 2 171 ? 32.594 3.816 -0.330 1.00 44.12 ? 170 PHE B C 1 ATOM 1925 O O . PHE B 2 171 ? 32.082 4.918 -0.153 1.00 46.25 ? 170 PHE B O 1 ATOM 1926 C CB . PHE B 2 171 ? 30.611 2.367 -0.471 1.00 40.56 ? 170 PHE B CB 1 ATOM 1927 C CG . PHE B 2 171 ? 30.750 2.186 -1.954 1.00 40.09 ? 170 PHE B CG 1 ATOM 1928 C CD1 . PHE B 2 171 ? 31.422 1.080 -2.466 1.00 39.84 ? 170 PHE B CD1 1 ATOM 1929 C CD2 . PHE B 2 171 ? 30.229 3.118 -2.839 1.00 38.87 ? 170 PHE B CD2 1 ATOM 1930 C CE1 . PHE B 2 171 ? 31.561 0.900 -3.829 1.00 39.07 ? 170 PHE B CE1 1 ATOM 1931 C CE2 . PHE B 2 171 ? 30.362 2.942 -4.204 1.00 38.55 ? 170 PHE B CE2 1 ATOM 1932 C CZ . PHE B 2 171 ? 31.032 1.837 -4.701 1.00 38.91 ? 170 PHE B CZ 1 ATOM 1933 N N . MET B 2 172 ? 33.720 3.629 -1.009 1.00 48.30 ? 171 MET B N 1 ATOM 1934 C CA . MET B 2 172 ? 34.379 4.715 -1.714 1.00 50.43 ? 171 MET B CA 1 ATOM 1935 C C . MET B 2 172 ? 33.833 4.719 -3.131 1.00 51.66 ? 171 MET B C 1 ATOM 1936 O O . MET B 2 172 ? 34.036 3.771 -3.892 1.00 49.83 ? 171 MET B O 1 ATOM 1937 C CB . MET B 2 172 ? 35.899 4.544 -1.714 1.00 52.69 ? 171 MET B CB 1 ATOM 1938 C CG . MET B 2 172 ? 36.667 5.653 -2.434 1.00 55.43 ? 171 MET B CG 1 ATOM 1939 S SD . MET B 2 172 ? 36.222 7.350 -1.984 1.00 57.14 ? 171 MET B SD 1 ATOM 1940 C CE . MET B 2 172 ? 36.963 7.485 -0.357 1.00 57.08 ? 171 MET B CE 1 ATOM 1941 N N . GLU B 2 173 ? 33.109 5.786 -3.451 1.00 52.95 ? 172 GLU B N 1 ATOM 1942 C CA . GLU B 2 173 ? 32.532 6.001 -4.776 1.00 52.75 ? 172 GLU B CA 1 ATOM 1943 C C . GLU B 2 173 ? 33.571 6.054 -5.907 1.00 51.17 ? 172 GLU B C 1 ATOM 1944 O O . GLU B 2 173 ? 34.763 6.288 -5.679 1.00 46.06 ? 172 GLU B O 1 ATOM 1945 C CB . GLU B 2 173 ? 31.666 7.277 -4.789 1.00 56.69 ? 172 GLU B CB 1 ATOM 1946 C CG . GLU B 2 173 ? 32.383 8.590 -4.422 1.00 60.52 ? 172 GLU B CG 1 ATOM 1947 C CD . GLU B 2 173 ? 32.320 8.968 -2.941 1.00 64.48 ? 172 GLU B CD 1 ATOM 1948 O OE1 . GLU B 2 173 ? 31.975 8.108 -2.090 1.00 67.00 ? 172 GLU B OE1 1 ATOM 1949 O OE2 . GLU B 2 173 ? 32.641 10.138 -2.622 1.00 66.80 ? 172 GLU B OE2 1 ATOM 1950 N N . SER B 2 174 ? 33.082 5.837 -7.125 1.00 50.61 ? 173 SER B N 1 ATOM 1951 C CA . SER B 2 174 ? 33.898 5.862 -8.331 1.00 50.59 ? 173 SER B CA 1 ATOM 1952 C C . SER B 2 174 ? 33.871 7.236 -9.011 1.00 52.60 ? 173 SER B C 1 ATOM 1953 O O . SER B 2 174 ? 33.056 8.113 -8.679 1.00 51.64 ? 173 SER B O 1 ATOM 1954 C CB . SER B 2 174 ? 33.406 4.784 -9.306 1.00 50.45 ? 173 SER B CB 1 ATOM 1955 O OG . SER B 2 174 ? 33.987 4.921 -10.591 1.00 48.43 ? 173 SER B OG 1 ATOM 1956 N N . GLY B 2 175 ? 34.790 7.401 -9.961 1.00 54.24 ? 174 GLY B N 1 ATOM 1957 C CA . GLY B 2 175 ? 34.846 8.568 -10.843 1.00 54.61 ? 174 GLY B CA 1 ATOM 1958 C C . GLY B 2 175 ? 34.021 8.433 -12.117 1.00 54.25 ? 174 GLY B C 1 ATOM 1959 O O . GLY B 2 175 ? 33.658 9.445 -12.723 1.00 56.50 ? 174 GLY B O 1 ATOM 1960 N N . GLU B 2 176 ? 33.740 7.194 -12.533 1.00 52.68 ? 175 GLU B N 1 ATOM 1961 C CA . GLU B 2 176 ? 32.942 6.918 -13.734 1.00 50.82 ? 175 GLU B CA 1 ATOM 1962 C C . GLU B 2 176 ? 31.537 6.402 -13.422 1.00 47.13 ? 175 GLU B C 1 ATOM 1963 O O . GLU B 2 176 ? 30.589 6.812 -14.082 1.00 47.02 ? 175 GLU B O 1 ATOM 1964 C CB . GLU B 2 176 ? 33.695 5.945 -14.656 1.00 53.46 ? 175 GLU B CB 1 ATOM 1965 C CG . GLU B 2 176 ? 32.962 5.495 -15.928 1.00 57.58 ? 175 GLU B CG 1 ATOM 1966 C CD . GLU B 2 176 ? 32.935 6.532 -17.052 1.00 59.92 ? 175 GLU B CD 1 ATOM 1967 O OE1 . GLU B 2 176 ? 33.012 7.748 -16.773 1.00 61.36 ? 175 GLU B OE1 1 ATOM 1968 O OE2 . GLU B 2 176 ? 32.823 6.122 -18.234 1.00 62.36 ? 175 GLU B OE2 1 ATOM 1969 N N . TRP B 2 177 ? 31.393 5.513 -12.441 1.00 45.75 ? 176 TRP B N 1 ATOM 1970 C CA . TRP B 2 177 ? 30.098 4.867 -12.167 1.00 45.87 ? 176 TRP B CA 1 ATOM 1971 C C . TRP B 2 177 ? 29.433 5.304 -10.866 1.00 45.30 ? 176 TRP B C 1 ATOM 1972 O O . TRP B 2 177 ? 30.087 5.822 -9.954 1.00 47.90 ? 176 TRP B O 1 ATOM 1973 C CB . TRP B 2 177 ? 30.258 3.346 -12.151 1.00 46.19 ? 176 TRP B CB 1 ATOM 1974 C CG . TRP B 2 177 ? 30.589 2.801 -13.472 1.00 45.73 ? 176 TRP B CG 1 ATOM 1975 C CD1 . TRP B 2 177 ? 29.720 2.502 -14.480 1.00 45.77 ? 176 TRP B CD1 1 ATOM 1976 C CD2 . TRP B 2 177 ? 31.895 2.500 -13.958 1.00 46.16 ? 176 TRP B CD2 1 ATOM 1977 N NE1 . TRP B 2 177 ? 30.408 2.026 -15.569 1.00 46.76 ? 176 TRP B NE1 1 ATOM 1978 C CE2 . TRP B 2 177 ? 31.747 2.016 -15.276 1.00 45.45 ? 176 TRP B CE2 1 ATOM 1979 C CE3 . TRP B 2 177 ? 33.181 2.595 -13.410 1.00 46.03 ? 176 TRP B CE3 1 ATOM 1980 C CZ2 . TRP B 2 177 ? 32.836 1.625 -16.054 1.00 45.20 ? 176 TRP B CZ2 1 ATOM 1981 C CZ3 . TRP B 2 177 ? 34.267 2.207 -14.188 1.00 45.53 ? 176 TRP B CZ3 1 ATOM 1982 C CH2 . TRP B 2 177 ? 34.084 1.726 -15.497 1.00 45.45 ? 176 TRP B CH2 1 ATOM 1983 N N . VAL B 2 178 ? 28.127 5.065 -10.792 1.00 42.44 ? 177 VAL B N 1 ATOM 1984 C CA . VAL B 2 178 ? 27.354 5.305 -9.576 1.00 43.79 ? 177 VAL B CA 1 ATOM 1985 C C . VAL B 2 178 ? 26.420 4.125 -9.316 1.00 43.24 ? 177 VAL B C 1 ATOM 1986 O O . VAL B 2 178 ? 25.865 3.569 -10.260 1.00 42.90 ? 177 VAL B O 1 ATOM 1987 C CB . VAL B 2 178 ? 26.560 6.635 -9.650 1.00 43.28 ? 177 VAL B CB 1 ATOM 1988 C CG1 . VAL B 2 178 ? 25.591 6.660 -10.831 1.00 43.92 ? 177 VAL B CG1 1 ATOM 1989 C CG2 . VAL B 2 178 ? 25.815 6.895 -8.347 1.00 42.79 ? 177 VAL B CG2 1 ATOM 1990 N N . ILE B 2 179 ? 26.262 3.738 -8.047 1.00 42.96 ? 178 ILE B N 1 ATOM 1991 C CA . ILE B 2 179 ? 25.323 2.675 -7.684 1.00 44.30 ? 178 ILE B CA 1 ATOM 1992 C C . ILE B 2 179 ? 23.925 3.296 -7.677 1.00 43.69 ? 178 ILE B C 1 ATOM 1993 O O . ILE B 2 179 ? 23.566 3.980 -6.729 1.00 43.80 ? 178 ILE B O 1 ATOM 1994 C CB . ILE B 2 179 ? 25.664 2.005 -6.315 1.00 45.39 ? 178 ILE B CB 1 ATOM 1995 C CG1 . ILE B 2 179 ? 26.870 1.060 -6.444 1.00 45.07 ? 178 ILE B CG1 1 ATOM 1996 C CG2 . ILE B 2 179 ? 24.490 1.175 -5.781 1.00 46.31 ? 178 ILE B CG2 1 ATOM 1997 C CD1 . ILE B 2 179 ? 28.201 1.752 -6.579 1.00 46.06 ? 178 ILE B CD1 1 ATOM 1998 N N . LYS B 2 180 ? 23.167 3.075 -8.753 1.00 45.42 ? 179 LYS B N 1 ATOM 1999 C CA . LYS B 2 180 ? 21.741 3.460 -8.839 1.00 48.98 ? 179 LYS B CA 1 ATOM 2000 C C . LYS B 2 180 ? 20.880 2.869 -7.734 1.00 51.46 ? 179 LYS B C 1 ATOM 2001 O O . LYS B 2 180 ? 20.005 3.542 -7.188 1.00 51.12 ? 179 LYS B O 1 ATOM 2002 C CB . LYS B 2 180 ? 21.119 2.989 -10.162 1.00 52.01 ? 179 LYS B CB 1 ATOM 2003 C CG . LYS B 2 180 ? 20.983 4.052 -11.234 1.00 56.39 ? 179 LYS B CG 1 ATOM 2004 C CD . LYS B 2 180 ? 20.104 3.569 -12.380 1.00 59.52 ? 179 LYS B CD 1 ATOM 2005 C CE . LYS B 2 180 ? 18.615 3.625 -12.040 1.00 61.57 ? 179 LYS B CE 1 ATOM 2006 N NZ . LYS B 2 180 ? 17.768 3.141 -13.169 1.00 63.18 ? 179 LYS B NZ 1 ATOM 2007 N N . GLU B 2 181 ? 21.123 1.595 -7.444 1.00 54.42 ? 180 GLU B N 1 ATOM 2008 C CA . GLU B 2 181 ? 20.208 0.771 -6.671 1.00 57.87 ? 180 GLU B CA 1 ATOM 2009 C C . GLU B 2 181 ? 20.975 -0.441 -6.161 1.00 55.24 ? 180 GLU B C 1 ATOM 2010 O O . GLU B 2 181 ? 21.929 -0.876 -6.807 1.00 55.90 ? 180 GLU B O 1 ATOM 2011 C CB . GLU B 2 181 ? 19.057 0.329 -7.577 1.00 63.78 ? 180 GLU B CB 1 ATOM 2012 C CG . GLU B 2 181 ? 17.937 -0.428 -6.883 1.00 71.55 ? 180 GLU B CG 1 ATOM 2013 C CD . GLU B 2 181 ? 16.760 -0.729 -7.809 1.00 80.00 ? 180 GLU B CD 1 ATOM 2014 O OE1 . GLU B 2 181 ? 15.698 -1.131 -7.283 1.00 87.68 ? 180 GLU B OE1 1 ATOM 2015 O OE2 . GLU B 2 181 ? 16.882 -0.571 -9.053 1.00 80.98 ? 180 GLU B OE2 1 ATOM 2016 N N . ALA B 2 182 ? 20.564 -0.973 -5.010 1.00 52.32 ? 181 ALA B N 1 ATOM 2017 C CA . ALA B 2 182 ? 21.245 -2.117 -4.391 1.00 50.76 ? 181 ALA B CA 1 ATOM 2018 C C . ALA B 2 182 ? 20.414 -2.734 -3.279 1.00 48.84 ? 181 ALA B C 1 ATOM 2019 O O . ALA B 2 182 ? 20.118 -2.062 -2.302 1.00 48.70 ? 181 ALA B O 1 ATOM 2020 C CB . ALA B 2 182 ? 22.601 -1.699 -3.835 1.00 50.80 ? 181 ALA B CB 1 ATOM 2021 N N . ARG B 2 183 ? 20.065 -4.011 -3.425 1.00 49.10 ? 182 ARG B N 1 ATOM 2022 C CA . ARG B 2 183 ? 19.290 -4.738 -2.420 1.00 51.36 ? 182 ARG B CA 1 ATOM 2023 C C . ARG B 2 183 ? 19.835 -6.142 -2.141 1.00 49.69 ? 182 ARG B C 1 ATOM 2024 O O . ARG B 2 183 ? 20.616 -6.696 -2.924 1.00 47.00 ? 182 ARG B O 1 ATOM 2025 C CB . ARG B 2 183 ? 17.808 -4.821 -2.835 1.00 54.74 ? 182 ARG B CB 1 ATOM 2026 C CG . ARG B 2 183 ? 16.960 -3.635 -2.362 1.00 59.25 ? 182 ARG B CG 1 ATOM 2027 C CD . ARG B 2 183 ? 15.540 -4.017 -1.961 1.00 61.93 ? 182 ARG B CD 1 ATOM 2028 N NE . ARG B 2 183 ? 15.519 -5.034 -0.904 1.00 66.57 ? 182 ARG B NE 1 ATOM 2029 C CZ . ARG B 2 183 ? 14.448 -5.377 -0.182 1.00 70.71 ? 182 ARG B CZ 1 ATOM 2030 N NH1 . ARG B 2 183 ? 13.265 -4.782 -0.354 1.00 73.43 ? 182 ARG B NH1 1 ATOM 2031 N NH2 . ARG B 2 183 ? 14.566 -6.330 0.740 1.00 71.01 ? 182 ARG B NH2 1 ATOM 2032 N N . GLY B 2 184 ? 19.412 -6.678 -0.993 1.00 46.54 ? 183 GLY B N 1 ATOM 2033 C CA . GLY B 2 184 ? 19.633 -8.059 -0.597 1.00 44.22 ? 183 GLY B CA 1 ATOM 2034 C C . GLY B 2 184 ? 18.299 -8.789 -0.485 1.00 43.91 ? 183 GLY B C 1 ATOM 2035 O O . GLY B 2 184 ? 17.340 -8.272 0.098 1.00 43.05 ? 183 GLY B O 1 ATOM 2036 N N . TRP B 2 185 ? 18.237 -9.989 -1.056 1.00 43.25 ? 184 TRP B N 1 ATOM 2037 C CA . TRP B 2 185 ? 17.075 -10.861 -0.940 1.00 43.48 ? 184 TRP B CA 1 ATOM 2038 C C . TRP B 2 185 ? 17.513 -12.233 -0.434 1.00 43.24 ? 184 TRP B C 1 ATOM 2039 O O . TRP B 2 185 ? 18.494 -12.795 -0.925 1.00 41.89 ? 184 TRP B O 1 ATOM 2040 C CB . TRP B 2 185 ? 16.407 -11.021 -2.295 1.00 44.39 ? 184 TRP B CB 1 ATOM 2041 C CG . TRP B 2 185 ? 15.866 -9.762 -2.846 1.00 45.08 ? 184 TRP B CG 1 ATOM 2042 C CD1 . TRP B 2 185 ? 16.386 -9.020 -3.868 1.00 46.16 ? 184 TRP B CD1 1 ATOM 2043 C CD2 . TRP B 2 185 ? 14.685 -9.086 -2.418 1.00 45.63 ? 184 TRP B CD2 1 ATOM 2044 N NE1 . TRP B 2 185 ? 15.596 -7.920 -4.107 1.00 47.63 ? 184 TRP B NE1 1 ATOM 2045 C CE2 . TRP B 2 185 ? 14.545 -7.934 -3.227 1.00 46.88 ? 184 TRP B CE2 1 ATOM 2046 C CE3 . TRP B 2 185 ? 13.729 -9.340 -1.429 1.00 44.98 ? 184 TRP B CE3 1 ATOM 2047 C CZ2 . TRP B 2 185 ? 13.485 -7.036 -3.072 1.00 46.10 ? 184 TRP B CZ2 1 ATOM 2048 C CZ3 . TRP B 2 185 ? 12.672 -8.450 -1.280 1.00 45.41 ? 184 TRP B CZ3 1 ATOM 2049 C CH2 . TRP B 2 185 ? 12.561 -7.311 -2.097 1.00 45.68 ? 184 TRP B CH2 1 ATOM 2050 N N . LYS B 2 186 ? 16.782 -12.759 0.545 1.00 43.34 ? 185 LYS B N 1 ATOM 2051 C CA . LYS B 2 186 ? 17.021 -14.097 1.076 1.00 44.19 ? 185 LYS B CA 1 ATOM 2052 C C . LYS B 2 186 ? 16.153 -15.089 0.308 1.00 44.88 ? 185 LYS B C 1 ATOM 2053 O O . LYS B 2 186 ? 14.999 -14.787 -0.003 1.00 44.50 ? 185 LYS B O 1 ATOM 2054 C CB . LYS B 2 186 ? 16.687 -14.137 2.565 1.00 43.89 ? 185 LYS B CB 1 ATOM 2055 C CG . LYS B 2 186 ? 16.997 -15.451 3.252 1.00 44.52 ? 185 LYS B CG 1 ATOM 2056 C CD . LYS B 2 186 ? 16.690 -15.357 4.735 1.00 45.16 ? 185 LYS B CD 1 ATOM 2057 C CE . LYS B 2 186 ? 16.644 -16.728 5.383 1.00 45.49 ? 185 LYS B CE 1 ATOM 2058 N NZ . LYS B 2 186 ? 16.305 -16.612 6.829 1.00 46.23 ? 185 LYS B NZ 1 ATOM 2059 N N . HIS B 2 187 ? 16.712 -16.260 -0.003 1.00 45.60 ? 186 HIS B N 1 ATOM 2060 C CA . HIS B 2 187 ? 15.983 -17.311 -0.723 1.00 45.86 ? 186 HIS B CA 1 ATOM 2061 C C . HIS B 2 187 ? 16.069 -18.661 -0.033 1.00 45.79 ? 186 HIS B C 1 ATOM 2062 O O . HIS B 2 187 ? 17.022 -18.956 0.695 1.00 44.94 ? 186 HIS B O 1 ATOM 2063 C CB . HIS B 2 187 ? 16.532 -17.494 -2.132 1.00 48.09 ? 186 HIS B CB 1 ATOM 2064 C CG . HIS B 2 187 ? 16.578 -16.241 -2.935 1.00 48.62 ? 186 HIS B CG 1 ATOM 2065 N ND1 . HIS B 2 187 ? 17.663 -15.395 -2.918 1.00 50.53 ? 186 HIS B ND1 1 ATOM 2066 C CD2 . HIS B 2 187 ? 15.684 -15.693 -3.788 1.00 49.13 ? 186 HIS B CD2 1 ATOM 2067 C CE1 . HIS B 2 187 ? 17.431 -14.375 -3.721 1.00 52.68 ? 186 HIS B CE1 1 ATOM 2068 N NE2 . HIS B 2 187 ? 16.236 -14.531 -4.262 1.00 51.31 ? 186 HIS B NE2 1 ATOM 2069 N N . TRP B 2 188 ? 15.051 -19.473 -0.296 1.00 46.58 ? 187 TRP B N 1 ATOM 2070 C CA . TRP B 2 188 ? 15.018 -20.877 0.062 1.00 45.90 ? 187 TRP B CA 1 ATOM 2071 C C . TRP B 2 188 ? 15.303 -21.576 -1.252 1.00 42.66 ? 187 TRP B C 1 ATOM 2072 O O . TRP B 2 188 ? 14.583 -21.368 -2.222 1.00 41.29 ? 187 TRP B O 1 ATOM 2073 C CB . TRP B 2 188 ? 13.646 -21.263 0.631 1.00 49.34 ? 187 TRP B CB 1 ATOM 2074 C CG . TRP B 2 188 ? 13.488 -20.904 2.094 1.00 54.15 ? 187 TRP B CG 1 ATOM 2075 C CD1 . TRP B 2 188 ? 13.451 -21.772 3.144 1.00 56.57 ? 187 TRP B CD1 1 ATOM 2076 C CD2 . TRP B 2 188 ? 13.388 -19.586 2.664 1.00 58.75 ? 187 TRP B CD2 1 ATOM 2077 N NE1 . TRP B 2 188 ? 13.318 -21.088 4.330 1.00 58.42 ? 187 TRP B NE1 1 ATOM 2078 C CE2 . TRP B 2 188 ? 13.279 -19.745 4.067 1.00 58.57 ? 187 TRP B CE2 1 ATOM 2079 C CE3 . TRP B 2 188 ? 13.374 -18.285 2.126 1.00 60.48 ? 187 TRP B CE3 1 ATOM 2080 C CZ2 . TRP B 2 188 ? 13.155 -18.656 4.942 1.00 59.44 ? 187 TRP B CZ2 1 ATOM 2081 C CZ3 . TRP B 2 188 ? 13.251 -17.196 2.999 1.00 60.58 ? 187 TRP B CZ3 1 ATOM 2082 C CH2 . TRP B 2 188 ? 13.142 -17.393 4.393 1.00 60.67 ? 187 TRP B CH2 1 ATOM 2083 N N . VAL B 2 189 ? 16.380 -22.352 -1.295 1.00 40.81 ? 188 VAL B N 1 ATOM 2084 C CA . VAL B 2 189 ? 16.828 -23.008 -2.518 1.00 41.62 ? 188 VAL B CA 1 ATOM 2085 C C . VAL B 2 189 ? 16.810 -24.509 -2.300 1.00 41.42 ? 188 VAL B C 1 ATOM 2086 O O . VAL B 2 189 ? 17.346 -24.983 -1.289 1.00 40.90 ? 188 VAL B O 1 ATOM 2087 C CB . VAL B 2 189 ? 18.259 -22.568 -2.891 1.00 41.64 ? 188 VAL B CB 1 ATOM 2088 C CG1 . VAL B 2 189 ? 18.697 -23.191 -4.210 1.00 40.32 ? 188 VAL B CG1 1 ATOM 2089 C CG2 . VAL B 2 189 ? 18.333 -21.050 -2.957 1.00 42.35 ? 188 VAL B CG2 1 ATOM 2090 N N . PHE B 2 190 ? 16.212 -25.249 -3.243 1.00 41.35 ? 189 PHE B N 1 ATOM 2091 C CA . PHE B 2 190 ? 16.144 -26.718 -3.157 1.00 41.81 ? 189 PHE B CA 1 ATOM 2092 C C . PHE B 2 190 ? 17.020 -27.390 -4.198 1.00 42.16 ? 189 PHE B C 1 ATOM 2093 O O . PHE B 2 190 ? 17.148 -26.896 -5.315 1.00 44.07 ? 189 PHE B O 1 ATOM 2094 C CB . PHE B 2 190 ? 14.714 -27.203 -3.299 1.00 41.67 ? 189 PHE B CB 1 ATOM 2095 C CG . PHE B 2 190 ? 13.834 -26.822 -2.143 1.00 42.94 ? 189 PHE B CG 1 ATOM 2096 C CD1 . PHE B 2 190 ? 13.763 -27.630 -1.014 1.00 43.16 ? 189 PHE B CD1 1 ATOM 2097 C CD2 . PHE B 2 190 ? 13.078 -25.652 -2.179 1.00 42.82 ? 189 PHE B CD2 1 ATOM 2098 C CE1 . PHE B 2 190 ? 12.946 -27.287 0.051 1.00 44.10 ? 189 PHE B CE1 1 ATOM 2099 C CE2 . PHE B 2 190 ? 12.266 -25.302 -1.114 1.00 43.82 ? 189 PHE B CE2 1 ATOM 2100 C CZ . PHE B 2 190 ? 12.199 -26.120 0.004 1.00 44.17 ? 189 PHE B CZ 1 ATOM 2101 N N . TYR B 2 191 ? 17.614 -28.518 -3.815 1.00 42.54 ? 190 TYR B N 1 ATOM 2102 C CA . TYR B 2 191 ? 18.504 -29.287 -4.680 1.00 43.25 ? 190 TYR B CA 1 ATOM 2103 C C . TYR B 2 191 ? 18.022 -30.726 -4.821 1.00 45.02 ? 190 TYR B C 1 ATOM 2104 O O . TYR B 2 191 ? 17.360 -31.256 -3.922 1.00 45.56 ? 190 TYR B O 1 ATOM 2105 C CB . TYR B 2 191 ? 19.911 -29.307 -4.103 1.00 42.50 ? 190 TYR B CB 1 ATOM 2106 C CG . TYR B 2 191 ? 20.577 -27.968 -4.055 1.00 41.21 ? 190 TYR B CG 1 ATOM 2107 C CD1 . TYR B 2 191 ? 20.308 -27.075 -3.031 1.00 40.47 ? 190 TYR B CD1 1 ATOM 2108 C CD2 . TYR B 2 191 ? 21.487 -27.592 -5.037 1.00 41.63 ? 190 TYR B CD2 1 ATOM 2109 C CE1 . TYR B 2 191 ? 20.924 -25.836 -2.987 1.00 41.17 ? 190 TYR B CE1 1 ATOM 2110 C CE2 . TYR B 2 191 ? 22.111 -26.360 -5.003 1.00 41.16 ? 190 TYR B CE2 1 ATOM 2111 C CZ . TYR B 2 191 ? 21.829 -25.486 -3.975 1.00 41.08 ? 190 TYR B CZ 1 ATOM 2112 O OH . TYR B 2 191 ? 22.449 -24.261 -3.935 1.00 42.01 ? 190 TYR B OH 1 ATOM 2113 N N . SER B 2 192 ? 18.400 -31.351 -5.937 1.00 46.53 ? 191 SER B N 1 ATOM 2114 C CA . SER B 2 192 ? 17.991 -32.720 -6.287 1.00 47.50 ? 191 SER B CA 1 ATOM 2115 C C . SER B 2 192 ? 18.246 -33.750 -5.201 1.00 48.34 ? 191 SER B C 1 ATOM 2116 O O . SER B 2 192 ? 17.425 -34.638 -5.009 1.00 48.04 ? 191 SER B O 1 ATOM 2117 C CB . SER B 2 192 ? 18.685 -33.177 -7.571 1.00 48.05 ? 191 SER B CB 1 ATOM 2118 O OG . SER B 2 192 ? 18.150 -32.482 -8.680 1.00 51.26 ? 191 SER B OG 1 ATOM 2119 N N . CYS B 2 193 ? 19.370 -33.624 -4.495 1.00 50.81 ? 192 CYS B N 1 ATOM 2120 C CA . CYS B 2 193 ? 19.714 -34.526 -3.384 1.00 53.06 ? 192 CYS B CA 1 ATOM 2121 C C . CYS B 2 193 ? 18.611 -34.667 -2.339 1.00 55.56 ? 192 CYS B C 1 ATOM 2122 O O . CYS B 2 193 ? 18.355 -35.765 -1.840 1.00 56.63 ? 192 CYS B O 1 ATOM 2123 C CB . CYS B 2 193 ? 20.975 -34.038 -2.651 1.00 53.43 ? 192 CYS B CB 1 ATOM 2124 S SG . CYS B 2 193 ? 20.799 -32.437 -1.803 1.00 54.61 ? 192 CYS B SG 1 ATOM 2125 N N . CYS B 2 194 ? 17.966 -33.540 -2.035 1.00 58.25 ? 193 CYS B N 1 ATOM 2126 C CA . CYS B 2 194 ? 17.361 -33.296 -0.738 1.00 58.92 ? 193 CYS B CA 1 ATOM 2127 C C . CYS B 2 194 ? 15.957 -32.688 -0.893 1.00 57.87 ? 193 CYS B C 1 ATOM 2128 O O . CYS B 2 194 ? 15.814 -31.464 -0.913 1.00 56.16 ? 193 CYS B O 1 ATOM 2129 C CB . CYS B 2 194 ? 18.294 -32.356 0.044 1.00 60.71 ? 193 CYS B CB 1 ATOM 2130 S SG . CYS B 2 194 ? 20.042 -32.872 0.062 1.00 64.21 ? 193 CYS B SG 1 ATOM 2131 N N . PRO B 2 195 ? 14.916 -33.541 -1.019 1.00 58.02 ? 194 PRO B N 1 ATOM 2132 C CA . PRO B 2 195 ? 13.545 -33.030 -1.159 1.00 58.16 ? 194 PRO B CA 1 ATOM 2133 C C . PRO B 2 195 ? 12.999 -32.337 0.090 1.00 58.19 ? 194 PRO B C 1 ATOM 2134 O O . PRO B 2 195 ? 12.270 -31.356 -0.024 1.00 60.03 ? 194 PRO B O 1 ATOM 2135 C CB . PRO B 2 195 ? 12.725 -34.294 -1.451 1.00 58.04 ? 194 PRO B CB 1 ATOM 2136 C CG . PRO B 2 195 ? 13.514 -35.406 -0.867 1.00 57.81 ? 194 PRO B CG 1 ATOM 2137 C CD . PRO B 2 195 ? 14.949 -35.017 -1.055 1.00 57.72 ? 194 PRO B CD 1 ATOM 2138 N N . THR B 2 196 ? 13.347 -32.847 1.263 1.00 59.09 ? 195 THR B N 1 ATOM 2139 C CA . THR B 2 196 ? 12.776 -32.366 2.515 1.00 60.87 ? 195 THR B CA 1 ATOM 2140 C C . THR B 2 196 ? 13.560 -31.226 3.161 1.00 62.38 ? 195 THR B C 1 ATOM 2141 O O . THR B 2 196 ? 12.979 -30.454 3.923 1.00 65.39 ? 195 THR B O 1 ATOM 2142 C CB . THR B 2 196 ? 12.654 -33.521 3.523 1.00 60.28 ? 195 THR B CB 1 ATOM 2143 O OG1 . THR B 2 196 ? 13.868 -34.284 3.524 1.00 60.77 ? 195 THR B OG1 1 ATOM 2144 C CG2 . THR B 2 196 ? 11.495 -34.424 3.143 1.00 59.74 ? 195 THR B CG2 1 ATOM 2145 N N . THR B 2 197 ? 14.854 -31.110 2.853 1.00 63.65 ? 196 THR B N 1 ATOM 2146 C CA . THR B 2 197 ? 15.760 -30.201 3.570 1.00 63.92 ? 196 THR B CA 1 ATOM 2147 C C . THR B 2 197 ? 16.208 -29.015 2.701 1.00 57.67 ? 196 THR B C 1 ATOM 2148 O O . THR B 2 197 ? 17.010 -29.200 1.786 1.00 56.70 ? 196 THR B O 1 ATOM 2149 C CB . THR B 2 197 ? 17.017 -30.959 4.072 1.00 68.83 ? 196 THR B CB 1 ATOM 2150 O OG1 . THR B 2 197 ? 16.624 -32.090 4.866 1.00 70.09 ? 196 THR B OG1 1 ATOM 2151 C CG2 . THR B 2 197 ? 17.898 -30.049 4.919 1.00 70.38 ? 196 THR B CG2 1 ATOM 2152 N N . PRO B 2 198 ? 15.723 -27.791 3.004 1.00 53.44 ? 197 PRO B N 1 ATOM 2153 C CA . PRO B 2 198 ? 16.086 -26.615 2.204 1.00 51.17 ? 197 PRO B CA 1 ATOM 2154 C C . PRO B 2 198 ? 17.471 -26.037 2.536 1.00 47.44 ? 197 PRO B C 1 ATOM 2155 O O . PRO B 2 198 ? 18.009 -26.267 3.621 1.00 44.62 ? 197 PRO B O 1 ATOM 2156 C CB . PRO B 2 198 ? 15.012 -25.603 2.590 1.00 51.75 ? 197 PRO B CB 1 ATOM 2157 C CG . PRO B 2 198 ? 14.760 -25.906 4.032 1.00 53.80 ? 197 PRO B CG 1 ATOM 2158 C CD . PRO B 2 198 ? 14.921 -27.402 4.182 1.00 54.04 ? 197 PRO B CD 1 ATOM 2159 N N . TYR B 2 199 ? 18.025 -25.290 1.588 1.00 44.78 ? 198 TYR B N 1 ATOM 2160 C CA . TYR B 2 199 ? 19.230 -24.498 1.810 1.00 44.72 ? 198 TYR B CA 1 ATOM 2161 C C . TYR B 2 199 ? 18.871 -23.020 1.673 1.00 43.62 ? 198 TYR B C 1 ATOM 2162 O O . TYR B 2 199 ? 17.801 -22.683 1.168 1.00 43.71 ? 198 TYR B O 1 ATOM 2163 C CB . TYR B 2 199 ? 20.313 -24.875 0.806 1.00 44.04 ? 198 TYR B CB 1 ATOM 2164 C CG . TYR B 2 199 ? 20.896 -26.251 1.006 1.00 43.76 ? 198 TYR B CG 1 ATOM 2165 C CD1 . TYR B 2 199 ? 20.231 -27.386 0.533 1.00 45.13 ? 198 TYR B CD1 1 ATOM 2166 C CD2 . TYR B 2 199 ? 22.121 -26.427 1.649 1.00 43.25 ? 198 TYR B CD2 1 ATOM 2167 C CE1 . TYR B 2 199 ? 20.770 -28.655 0.695 1.00 44.70 ? 198 TYR B CE1 1 ATOM 2168 C CE2 . TYR B 2 199 ? 22.667 -27.692 1.820 1.00 44.03 ? 198 TYR B CE2 1 ATOM 2169 C CZ . TYR B 2 199 ? 21.989 -28.803 1.340 1.00 43.98 ? 198 TYR B CZ 1 ATOM 2170 O OH . TYR B 2 199 ? 22.516 -30.060 1.503 1.00 42.91 ? 198 TYR B OH 1 ATOM 2171 N N . LEU B 2 200 ? 19.768 -22.147 2.124 1.00 42.80 ? 199 LEU B N 1 ATOM 2172 C CA . LEU B 2 200 ? 19.494 -20.716 2.185 1.00 42.98 ? 199 LEU B CA 1 ATOM 2173 C C . LEU B 2 200 ? 20.600 -19.909 1.530 1.00 42.02 ? 199 LEU B C 1 ATOM 2174 O O . LEU B 2 200 ? 21.776 -20.111 1.838 1.00 40.43 ? 199 LEU B O 1 ATOM 2175 C CB . LEU B 2 200 ? 19.347 -20.285 3.639 1.00 43.91 ? 199 LEU B CB 1 ATOM 2176 C CG . LEU B 2 200 ? 18.227 -20.979 4.428 1.00 45.07 ? 199 LEU B CG 1 ATOM 2177 C CD1 . LEU B 2 200 ? 18.407 -20.738 5.919 1.00 44.46 ? 199 LEU B CD1 1 ATOM 2178 C CD2 . LEU B 2 200 ? 16.842 -20.531 3.961 1.00 45.54 ? 199 LEU B CD2 1 ATOM 2179 N N . ASP B 2 201 ? 20.219 -19.014 0.616 1.00 42.03 ? 200 ASP B N 1 ATOM 2180 C CA . ASP B 2 201 ? 21.123 -17.969 0.135 1.00 43.25 ? 200 ASP B CA 1 ATOM 2181 C C . ASP B 2 201 ? 20.605 -16.559 0.465 1.00 41.87 ? 200 ASP B C 1 ATOM 2182 O O . ASP B 2 201 ? 19.408 -16.358 0.711 1.00 38.78 ? 200 ASP B O 1 ATOM 2183 C CB . ASP B 2 201 ? 21.458 -18.133 -1.368 1.00 44.85 ? 200 ASP B CB 1 ATOM 2184 C CG . ASP B 2 201 ? 20.416 -17.510 -2.311 1.00 47.31 ? 200 ASP B CG 1 ATOM 2185 O OD1 . ASP B 2 201 ? 20.083 -16.317 -2.163 1.00 49.10 ? 200 ASP B OD1 1 ATOM 2186 O OD2 . ASP B 2 201 ? 19.963 -18.203 -3.251 1.00 49.87 ? 200 ASP B OD2 1 ATOM 2187 N N . ILE B 2 202 ? 21.541 -15.608 0.489 1.00 40.87 ? 201 ILE B N 1 ATOM 2188 C CA . ILE B 2 202 ? 21.245 -14.177 0.447 1.00 39.32 ? 201 ILE B CA 1 ATOM 2189 C C . ILE B 2 202 ? 21.976 -13.638 -0.788 1.00 38.74 ? 201 ILE B C 1 ATOM 2190 O O . ILE B 2 202 ? 23.211 -13.640 -0.825 1.00 38.14 ? 201 ILE B O 1 ATOM 2191 C CB . ILE B 2 202 ? 21.720 -13.434 1.719 1.00 39.38 ? 201 ILE B CB 1 ATOM 2192 C CG1 . ILE B 2 202 ? 21.108 -14.048 2.979 1.00 39.72 ? 201 ILE B CG1 1 ATOM 2193 C CG2 . ILE B 2 202 ? 21.311 -11.968 1.676 1.00 40.56 ? 201 ILE B CG2 1 ATOM 2194 C CD1 . ILE B 2 202 ? 21.748 -13.570 4.265 1.00 40.00 ? 201 ILE B CD1 1 ATOM 2195 N N . THR B 2 203 ? 21.219 -13.204 -1.800 1.00 37.71 ? 202 THR B N 1 ATOM 2196 C CA . THR B 2 203 ? 21.793 -12.583 -3.000 1.00 36.79 ? 202 THR B CA 1 ATOM 2197 C C . THR B 2 203 ? 21.750 -11.054 -2.905 1.00 36.30 ? 202 THR B C 1 ATOM 2198 O O . THR B 2 203 ? 20.673 -10.457 -2.898 1.00 35.22 ? 202 THR B O 1 ATOM 2199 C CB . THR B 2 203 ? 21.060 -13.013 -4.282 1.00 35.69 ? 202 THR B CB 1 ATOM 2200 O OG1 . THR B 2 203 ? 21.068 -14.435 -4.387 1.00 37.31 ? 202 THR B OG1 1 ATOM 2201 C CG2 . THR B 2 203 ? 21.737 -12.437 -5.512 1.00 35.99 ? 202 THR B CG2 1 ATOM 2202 N N . TYR B 2 204 ? 22.927 -10.437 -2.828 1.00 35.88 ? 203 TYR B N 1 ATOM 2203 C CA . TYR B 2 204 ? 23.058 -8.986 -2.898 1.00 35.39 ? 203 TYR B CA 1 ATOM 2204 C C . TYR B 2 204 ? 23.328 -8.605 -4.338 1.00 35.53 ? 203 TYR B C 1 ATOM 2205 O O . TYR B 2 204 ? 24.193 -9.213 -4.970 1.00 35.64 ? 203 TYR B O 1 ATOM 2206 C CB . TYR B 2 204 ? 24.200 -8.497 -1.999 1.00 34.42 ? 203 TYR B CB 1 ATOM 2207 C CG . TYR B 2 204 ? 23.934 -8.708 -0.527 1.00 34.02 ? 203 TYR B CG 1 ATOM 2208 C CD1 . TYR B 2 204 ? 23.285 -7.736 0.239 1.00 34.66 ? 203 TYR B CD1 1 ATOM 2209 C CD2 . TYR B 2 204 ? 24.315 -9.883 0.101 1.00 34.25 ? 203 TYR B CD2 1 ATOM 2210 C CE1 . TYR B 2 204 ? 23.032 -7.937 1.592 1.00 35.19 ? 203 TYR B CE1 1 ATOM 2211 C CE2 . TYR B 2 204 ? 24.074 -10.084 1.450 1.00 34.79 ? 203 TYR B CE2 1 ATOM 2212 C CZ . TYR B 2 204 ? 23.437 -9.123 2.192 1.00 35.30 ? 203 TYR B CZ 1 ATOM 2213 O OH . TYR B 2 204 ? 23.213 -9.389 3.527 1.00 36.62 ? 203 TYR B OH 1 ATOM 2214 N N . HIS B 2 205 ? 22.583 -7.626 -4.858 1.00 35.86 ? 204 HIS B N 1 ATOM 2215 C CA . HIS B 2 205 ? 22.862 -7.044 -6.180 1.00 37.01 ? 204 HIS B CA 1 ATOM 2216 C C . HIS B 2 205 ? 23.000 -5.529 -6.071 1.00 39.00 ? 204 HIS B C 1 ATOM 2217 O O . HIS B 2 205 ? 22.417 -4.914 -5.184 1.00 38.70 ? 204 HIS B O 1 ATOM 2218 C CB . HIS B 2 205 ? 21.772 -7.405 -7.204 1.00 37.31 ? 204 HIS B CB 1 ATOM 2219 C CG . HIS B 2 205 ? 20.512 -6.600 -7.067 1.00 38.40 ? 204 HIS B CG 1 ATOM 2220 N ND1 . HIS B 2 205 ? 19.460 -6.992 -6.266 1.00 38.69 ? 204 HIS B ND1 1 ATOM 2221 C CD2 . HIS B 2 205 ? 20.143 -5.420 -7.621 1.00 38.82 ? 204 HIS B CD2 1 ATOM 2222 C CE1 . HIS B 2 205 ? 18.503 -6.084 -6.324 1.00 39.18 ? 204 HIS B CE1 1 ATOM 2223 N NE2 . HIS B 2 205 ? 18.889 -5.122 -7.145 1.00 39.21 ? 204 HIS B NE2 1 ATOM 2224 N N . PHE B 2 206 ? 23.783 -4.939 -6.971 1.00 41.46 ? 205 PHE B N 1 ATOM 2225 C CA . PHE B 2 206 ? 23.813 -3.490 -7.147 1.00 42.59 ? 205 PHE B CA 1 ATOM 2226 C C . PHE B 2 206 ? 23.806 -3.159 -8.642 1.00 42.09 ? 205 PHE B C 1 ATOM 2227 O O . PHE B 2 206 ? 24.470 -3.819 -9.432 1.00 39.96 ? 205 PHE B O 1 ATOM 2228 C CB . PHE B 2 206 ? 25.016 -2.865 -6.426 1.00 44.51 ? 205 PHE B CB 1 ATOM 2229 C CG . PHE B 2 206 ? 26.343 -3.337 -6.934 1.00 47.09 ? 205 PHE B CG 1 ATOM 2230 C CD1 . PHE B 2 206 ? 26.936 -4.485 -6.415 1.00 50.24 ? 205 PHE B CD1 1 ATOM 2231 C CD2 . PHE B 2 206 ? 27.008 -2.637 -7.940 1.00 49.12 ? 205 PHE B CD2 1 ATOM 2232 C CE1 . PHE B 2 206 ? 28.171 -4.924 -6.896 1.00 52.06 ? 205 PHE B CE1 1 ATOM 2233 C CE2 . PHE B 2 206 ? 28.239 -3.075 -8.427 1.00 50.51 ? 205 PHE B CE2 1 ATOM 2234 C CZ . PHE B 2 206 ? 28.824 -4.219 -7.903 1.00 50.27 ? 205 PHE B CZ 1 ATOM 2235 N N . VAL B 2 207 ? 23.027 -2.150 -9.018 1.00 43.66 ? 206 VAL B N 1 ATOM 2236 C CA . VAL B 2 207 ? 22.960 -1.674 -10.395 1.00 43.51 ? 206 VAL B CA 1 ATOM 2237 C C . VAL B 2 207 ? 23.885 -0.467 -10.508 1.00 44.25 ? 206 VAL B C 1 ATOM 2238 O O . VAL B 2 207 ? 23.648 0.561 -9.870 1.00 42.29 ? 206 VAL B O 1 ATOM 2239 C CB . VAL B 2 207 ? 21.518 -1.271 -10.780 1.00 42.94 ? 206 VAL B CB 1 ATOM 2240 C CG1 . VAL B 2 207 ? 21.455 -0.762 -12.218 1.00 43.10 ? 206 VAL B CG1 1 ATOM 2241 C CG2 . VAL B 2 207 ? 20.576 -2.449 -10.595 1.00 42.55 ? 206 VAL B CG2 1 ATOM 2242 N N . MET B 2 208 ? 24.940 -0.603 -11.306 1.00 46.97 ? 207 MET B N 1 ATOM 2243 C CA . MET B 2 208 ? 25.882 0.499 -11.545 1.00 50.12 ? 207 MET B CA 1 ATOM 2244 C C . MET B 2 208 ? 25.602 1.165 -12.899 1.00 52.33 ? 207 MET B C 1 ATOM 2245 O O . MET B 2 208 ? 25.471 0.487 -13.915 1.00 53.55 ? 207 MET B O 1 ATOM 2246 C CB . MET B 2 208 ? 27.343 0.040 -11.428 1.00 50.33 ? 207 MET B CB 1 ATOM 2247 C CG . MET B 2 208 ? 27.786 -1.053 -12.386 1.00 51.43 ? 207 MET B CG 1 ATOM 2248 S SD . MET B 2 208 ? 29.430 -1.687 -11.984 1.00 51.39 ? 207 MET B SD 1 ATOM 2249 C CE . MET B 2 208 ? 30.490 -0.529 -12.844 1.00 52.79 ? 207 MET B CE 1 ATOM 2250 N N . GLN B 2 209 ? 25.487 2.494 -12.881 1.00 55.72 ? 208 GLN B N 1 ATOM 2251 C CA . GLN B 2 209 ? 25.194 3.313 -14.056 1.00 56.74 ? 208 GLN B CA 1 ATOM 2252 C C . GLN B 2 209 ? 26.367 4.243 -14.331 1.00 56.99 ? 208 GLN B C 1 ATOM 2253 O O . GLN B 2 209 ? 26.981 4.749 -13.404 1.00 61.04 ? 208 GLN B O 1 ATOM 2254 C CB . GLN B 2 209 ? 23.946 4.154 -13.791 1.00 60.72 ? 208 GLN B CB 1 ATOM 2255 C CG . GLN B 2 209 ? 23.494 5.024 -14.960 1.00 64.75 ? 208 GLN B CG 1 ATOM 2256 C CD . GLN B 2 209 ? 22.174 5.727 -14.692 1.00 66.55 ? 208 GLN B CD 1 ATOM 2257 O OE1 . GLN B 2 209 ? 21.957 6.294 -13.618 1.00 69.78 ? 208 GLN B OE1 1 ATOM 2258 N NE2 . GLN B 2 209 ? 21.286 5.700 -15.676 1.00 69.35 ? 208 GLN B NE2 1 ATOM 2259 N N . ARG B 2 210 ? 26.661 4.479 -15.604 1.00 59.48 ? 209 ARG B N 1 ATOM 2260 C CA . ARG B 2 210 ? 27.759 5.366 -16.003 1.00 59.77 ? 209 ARG B CA 1 ATOM 2261 C C . ARG B 2 210 ? 27.352 6.830 -15.839 1.00 56.21 ? 209 ARG B C 1 ATOM 2262 O O . ARG B 2 210 ? 26.215 7.189 -16.132 1.00 54.32 ? 209 ARG B O 1 ATOM 2263 C CB . ARG B 2 210 ? 28.140 5.089 -17.459 1.00 64.52 ? 209 ARG B CB 1 ATOM 2264 C CG . ARG B 2 210 ? 29.485 5.650 -17.901 1.00 68.93 ? 209 ARG B CG 1 ATOM 2265 C CD . ARG B 2 210 ? 29.730 5.418 -19.390 1.00 74.10 ? 209 ARG B CD 1 ATOM 2266 N NE . ARG B 2 210 ? 29.536 4.016 -19.781 1.00 79.06 ? 209 ARG B NE 1 ATOM 2267 C CZ . ARG B 2 210 ? 30.383 3.012 -19.530 1.00 81.15 ? 209 ARG B CZ 1 ATOM 2268 N NH1 . ARG B 2 210 ? 31.529 3.214 -18.875 1.00 81.95 ? 209 ARG B NH1 1 ATOM 2269 N NH2 . ARG B 2 210 ? 30.080 1.782 -19.939 1.00 80.65 ? 209 ARG B NH2 1 ATOM 2270 N N . LEU B 2 211 ? 28.280 7.659 -15.359 1.00 56.47 ? 210 LEU B N 1 ATOM 2271 C CA . LEU B 2 211 ? 28.088 9.118 -15.272 1.00 57.72 ? 210 LEU B CA 1 ATOM 2272 C C . LEU B 2 211 ? 28.298 9.790 -16.645 1.00 59.94 ? 210 LEU B C 1 ATOM 2273 O O . LEU B 2 211 ? 29.007 9.249 -17.496 1.00 58.30 ? 210 LEU B O 1 ATOM 2274 C CB . LEU B 2 211 ? 29.072 9.739 -14.266 1.00 57.29 ? 210 LEU B CB 1 ATOM 2275 C CG . LEU B 2 211 ? 28.947 9.386 -12.778 1.00 57.77 ? 210 LEU B CG 1 ATOM 2276 C CD1 . LEU B 2 211 ? 30.164 9.874 -12.005 1.00 56.93 ? 210 LEU B CD1 1 ATOM 2277 C CD2 . LEU B 2 211 ? 27.674 9.965 -12.174 1.00 57.52 ? 210 LEU B CD2 1 ATOM 2278 N N . PRO B 2 212 ? 27.698 10.982 -16.860 1.00 63.94 ? 211 PRO B N 1 ATOM 2279 C CA . PRO B 2 212 ? 27.970 11.739 -18.090 1.00 64.84 ? 211 PRO B CA 1 ATOM 2280 C C . PRO B 2 212 ? 29.371 12.355 -18.109 1.00 65.26 ? 211 PRO B C 1 ATOM 2281 O O . PRO B 2 212 ? 29.844 12.871 -17.098 1.00 65.90 ? 211 PRO B O 1 ATOM 2282 C CB . PRO B 2 212 ? 26.906 12.840 -18.062 1.00 64.55 ? 211 PRO B CB 1 ATOM 2283 C CG . PRO B 2 212 ? 26.632 13.050 -16.619 1.00 64.21 ? 211 PRO B CG 1 ATOM 2284 C CD . PRO B 2 212 ? 26.716 11.680 -16.007 1.00 64.82 ? 211 PRO B CD 1 ATOM 2285 O OXT . PRO B 2 212 ? 30.062 12.356 -19.129 1.00 66.93 ? 211 PRO B OXT 1 ATOM 2286 N N . ASP C 3 1 ? 26.539 -6.011 38.097 1.00 91.60 ? 1 ASP C N 1 ATOM 2287 C CA . ASP C 3 1 ? 26.168 -7.230 38.883 1.00 92.42 ? 1 ASP C CA 1 ATOM 2288 C C . ASP C 3 1 ? 24.649 -7.342 39.094 1.00 90.16 ? 1 ASP C C 1 ATOM 2289 O O . ASP C 3 1 ? 23.926 -6.339 39.059 1.00 90.13 ? 1 ASP C O 1 ATOM 2290 C CB . ASP C 3 1 ? 26.901 -7.250 40.231 1.00 93.26 ? 1 ASP C CB 1 ATOM 2291 C CG . ASP C 3 1 ? 28.418 -7.345 40.080 1.00 95.44 ? 1 ASP C CG 1 ATOM 2292 O OD1 . ASP C 3 1 ? 28.980 -6.752 39.128 1.00 91.99 ? 1 ASP C OD1 1 ATOM 2293 O OD2 . ASP C 3 1 ? 29.049 -8.014 40.927 1.00 97.37 ? 1 ASP C OD2 1 ATOM 2294 N N . ILE C 3 2 ? 24.189 -8.574 39.315 1.00 83.72 ? 2 ILE C N 1 ATOM 2295 C CA . ILE C 3 2 ? 22.763 -8.905 39.382 1.00 79.60 ? 2 ILE C CA 1 ATOM 2296 C C . ILE C 3 2 ? 22.308 -9.017 40.840 1.00 77.79 ? 2 ILE C C 1 ATOM 2297 O O . ILE C 3 2 ? 22.780 -9.887 41.569 1.00 69.29 ? 2 ILE C O 1 ATOM 2298 C CB . ILE C 3 2 ? 22.476 -10.242 38.656 1.00 77.70 ? 2 ILE C CB 1 ATOM 2299 C CG1 . ILE C 3 2 ? 22.868 -10.144 37.177 1.00 77.04 ? 2 ILE C CG1 1 ATOM 2300 C CG2 . ILE C 3 2 ? 21.006 -10.633 38.787 1.00 77.27 ? 2 ILE C CG2 1 ATOM 2301 C CD1 . ILE C 3 2 ? 23.007 -11.485 36.487 1.00 77.00 ? 2 ILE C CD1 1 ATOM 2302 N N . VAL C 3 3 ? 21.383 -8.147 41.249 1.00 77.89 ? 3 VAL C N 1 ATOM 2303 C CA . VAL C 3 3 ? 20.789 -8.207 42.589 1.00 76.83 ? 3 VAL C CA 1 ATOM 2304 C C . VAL C 3 3 ? 19.724 -9.308 42.615 1.00 72.18 ? 3 VAL C C 1 ATOM 2305 O O . VAL C 3 3 ? 18.985 -9.503 41.642 1.00 65.95 ? 3 VAL C O 1 ATOM 2306 C CB . VAL C 3 3 ? 20.177 -6.850 43.017 1.00 82.70 ? 3 VAL C CB 1 ATOM 2307 C CG1 . VAL C 3 3 ? 19.481 -6.959 44.378 1.00 84.75 ? 3 VAL C CG1 1 ATOM 2308 C CG2 . VAL C 3 3 ? 21.251 -5.762 43.046 1.00 82.72 ? 3 VAL C CG2 1 ATOM 2309 N N . ILE C 3 4 ? 19.657 -10.007 43.745 1.00 70.21 ? 4 ILE C N 1 ATOM 2310 C CA . ILE C 3 4 ? 18.801 -11.178 43.926 1.00 69.44 ? 4 ILE C CA 1 ATOM 2311 C C . ILE C 3 4 ? 17.970 -11.023 45.200 1.00 66.93 ? 4 ILE C C 1 ATOM 2312 O O . ILE C 3 4 ? 18.512 -10.660 46.250 1.00 69.43 ? 4 ILE C O 1 ATOM 2313 C CB . ILE C 3 4 ? 19.684 -12.441 44.019 1.00 71.45 ? 4 ILE C CB 1 ATOM 2314 C CG1 . ILE C 3 4 ? 20.015 -12.960 42.620 1.00 68.27 ? 4 ILE C CG1 1 ATOM 2315 C CG2 . ILE C 3 4 ? 19.003 -13.547 44.799 1.00 75.45 ? 4 ILE C CG2 1 ATOM 2316 C CD1 . ILE C 3 4 ? 21.144 -13.958 42.601 1.00 66.37 ? 4 ILE C CD1 1 ATOM 2317 N N . THR C 3 5 ? 16.675 -11.335 45.111 1.00 62.51 ? 5 THR C N 1 ATOM 2318 C CA . THR C 3 5 ? 15.771 -11.265 46.267 1.00 63.67 ? 5 THR C CA 1 ATOM 2319 C C . THR C 3 5 ? 15.071 -12.610 46.499 1.00 64.35 ? 5 THR C C 1 ATOM 2320 O O . THR C 3 5 ? 14.387 -13.115 45.610 1.00 63.93 ? 5 THR C O 1 ATOM 2321 C CB . THR C 3 5 ? 14.720 -10.138 46.106 1.00 61.79 ? 5 THR C CB 1 ATOM 2322 O OG1 . THR C 3 5 ? 13.907 -10.381 44.955 1.00 61.81 ? 5 THR C OG1 1 ATOM 2323 C CG2 . THR C 3 5 ? 15.400 -8.780 45.954 1.00 61.44 ? 5 THR C CG2 1 ATOM 2324 N N . GLN C 3 6 ? 15.252 -13.178 47.694 1.00 66.65 ? 6 GLN C N 1 ATOM 2325 C CA . GLN C 3 6 ? 14.596 -14.434 48.090 1.00 67.88 ? 6 GLN C CA 1 ATOM 2326 C C . GLN C 3 6 ? 13.295 -14.214 48.854 1.00 69.26 ? 6 GLN C C 1 ATOM 2327 O O . GLN C 3 6 ? 13.275 -13.474 49.841 1.00 69.66 ? 6 GLN C O 1 ATOM 2328 C CB . GLN C 3 6 ? 15.511 -15.253 48.994 1.00 67.24 ? 6 GLN C CB 1 ATOM 2329 C CG . GLN C 3 6 ? 16.725 -15.800 48.291 1.00 66.26 ? 6 GLN C CG 1 ATOM 2330 C CD . GLN C 3 6 ? 17.492 -16.784 49.146 1.00 65.29 ? 6 GLN C CD 1 ATOM 2331 O OE1 . GLN C 3 6 ? 18.630 -16.533 49.524 1.00 62.76 ? 6 GLN C OE1 1 ATOM 2332 N NE2 . GLN C 3 6 ? 16.873 -17.916 49.448 1.00 66.29 ? 6 GLN C NE2 1 ATOM 2333 N N . SER C 3 7 ? 12.227 -14.882 48.414 1.00 70.43 ? 7 SER C N 1 ATOM 2334 C CA . SER C 3 7 ? 10.990 -14.979 49.194 1.00 72.59 ? 7 SER C CA 1 ATOM 2335 C C . SER C 3 7 ? 10.634 -16.462 49.437 1.00 73.61 ? 7 SER C C 1 ATOM 2336 O O . SER C 3 7 ? 11.059 -17.326 48.668 1.00 73.99 ? 7 SER C O 1 ATOM 2337 C CB . SER C 3 7 ? 9.841 -14.223 48.502 1.00 72.45 ? 7 SER C CB 1 ATOM 2338 O OG . SER C 3 7 ? 9.248 -14.963 47.450 1.00 70.02 ? 7 SER C OG 1 ATOM 2339 N N . PRO C 3 8 ? 9.908 -16.781 50.512 1.00 76.22 ? 8 PRO C N 1 ATOM 2340 C CA . PRO C 3 8 ? 9.594 -15.861 51.608 1.00 76.32 ? 8 PRO C CA 1 ATOM 2341 C C . PRO C 3 8 ? 10.806 -15.619 52.513 1.00 76.37 ? 8 PRO C C 1 ATOM 2342 O O . PRO C 3 8 ? 11.686 -16.475 52.609 1.00 73.37 ? 8 PRO C O 1 ATOM 2343 C CB . PRO C 3 8 ? 8.476 -16.591 52.374 1.00 78.71 ? 8 PRO C CB 1 ATOM 2344 C CG . PRO C 3 8 ? 8.477 -17.997 51.864 1.00 77.90 ? 8 PRO C CG 1 ATOM 2345 C CD . PRO C 3 8 ? 8.953 -17.899 50.452 1.00 77.20 ? 8 PRO C CD 1 ATOM 2346 N N . SER C 3 9 ? 10.838 -14.455 53.160 1.00 79.21 ? 9 SER C N 1 ATOM 2347 C CA . SER C 3 9 ? 11.939 -14.071 54.046 1.00 80.22 ? 9 SER C CA 1 ATOM 2348 C C . SER C 3 9 ? 12.083 -15.044 55.206 1.00 78.25 ? 9 SER C C 1 ATOM 2349 O O . SER C 3 9 ? 13.170 -15.560 55.463 1.00 74.29 ? 9 SER C O 1 ATOM 2350 C CB . SER C 3 9 ? 11.716 -12.658 54.590 1.00 83.65 ? 9 SER C CB 1 ATOM 2351 O OG . SER C 3 9 ? 12.811 -12.237 55.390 1.00 89.27 ? 9 SER C OG 1 ATOM 2352 N N . LEU C 3 10 ? 10.972 -15.271 55.902 1.00 81.11 ? 10 LEU C N 1 ATOM 2353 C CA . LEU C 3 10 ? 10.886 -16.258 56.975 1.00 81.96 ? 10 LEU C CA 1 ATOM 2354 C C . LEU C 3 10 ? 9.788 -17.255 56.610 1.00 79.11 ? 10 LEU C C 1 ATOM 2355 O O . LEU C 3 10 ? 8.714 -16.847 56.162 1.00 76.92 ? 10 LEU C O 1 ATOM 2356 C CB . LEU C 3 10 ? 10.553 -15.568 58.295 1.00 85.28 ? 10 LEU C CB 1 ATOM 2357 C CG . LEU C 3 10 ? 11.102 -16.268 59.540 1.00 90.78 ? 10 LEU C CG 1 ATOM 2358 C CD1 . LEU C 3 10 ? 12.538 -15.831 59.814 1.00 91.42 ? 10 LEU C CD1 1 ATOM 2359 C CD2 . LEU C 3 10 ? 10.219 -15.990 60.748 1.00 93.47 ? 10 LEU C CD2 1 ATOM 2360 N N . LEU C 3 11 ? 10.055 -18.548 56.793 1.00 77.05 ? 11 LEU C N 1 ATOM 2361 C CA . LEU C 3 11 ? 9.101 -19.600 56.429 1.00 77.51 ? 11 LEU C CA 1 ATOM 2362 C C . LEU C 3 11 ? 8.866 -20.563 57.592 1.00 77.53 ? 11 LEU C C 1 ATOM 2363 O O . LEU C 3 11 ? 9.821 -21.079 58.193 1.00 72.43 ? 11 LEU C O 1 ATOM 2364 C CB . LEU C 3 11 ? 9.589 -20.359 55.191 1.00 79.58 ? 11 LEU C CB 1 ATOM 2365 C CG . LEU C 3 11 ? 8.792 -21.579 54.697 1.00 80.02 ? 11 LEU C CG 1 ATOM 2366 C CD1 . LEU C 3 11 ? 7.292 -21.320 54.641 1.00 81.29 ? 11 LEU C CD1 1 ATOM 2367 C CD2 . LEU C 3 11 ? 9.308 -22.004 53.330 1.00 79.64 ? 11 LEU C CD2 1 ATOM 2368 N N . SER C 3 12 ? 7.583 -20.778 57.898 1.00 78.52 ? 12 SER C N 1 ATOM 2369 C CA . SER C 3 12 ? 7.131 -21.733 58.908 1.00 76.58 ? 12 SER C CA 1 ATOM 2370 C C . SER C 3 12 ? 6.375 -22.886 58.231 1.00 71.81 ? 12 SER C C 1 ATOM 2371 O O . SER C 3 12 ? 5.448 -22.644 57.454 1.00 67.02 ? 12 SER C O 1 ATOM 2372 C CB . SER C 3 12 ? 6.228 -21.032 59.924 1.00 77.36 ? 12 SER C CB 1 ATOM 2373 O OG . SER C 3 12 ? 6.224 -21.734 61.152 1.00 80.64 ? 12 SER C OG 1 ATOM 2374 N N . ALA C 3 13 ? 6.779 -24.125 58.520 1.00 68.67 ? 13 ALA C N 1 ATOM 2375 C CA . ALA C 3 13 ? 6.129 -25.313 57.945 1.00 67.20 ? 13 ALA C CA 1 ATOM 2376 C C . ALA C 3 13 ? 6.467 -26.579 58.729 1.00 64.88 ? 13 ALA C C 1 ATOM 2377 O O . ALA C 3 13 ? 7.559 -26.692 59.296 1.00 62.67 ? 13 ALA C O 1 ATOM 2378 C CB . ALA C 3 13 ? 6.528 -25.483 56.485 1.00 67.78 ? 13 ALA C CB 1 ATOM 2379 N N . SER C 3 14 ? 5.530 -27.530 58.740 1.00 62.87 ? 14 SER C N 1 ATOM 2380 C CA . SER C 3 14 ? 5.680 -28.781 59.496 1.00 61.73 ? 14 SER C CA 1 ATOM 2381 C C . SER C 3 14 ? 6.405 -29.863 58.694 1.00 60.62 ? 14 SER C C 1 ATOM 2382 O O . SER C 3 14 ? 6.614 -29.722 57.487 1.00 58.48 ? 14 SER C O 1 ATOM 2383 C CB . SER C 3 14 ? 4.307 -29.299 59.932 1.00 61.89 ? 14 SER C CB 1 ATOM 2384 O OG . SER C 3 14 ? 3.511 -29.626 58.809 1.00 64.13 ? 14 SER C OG 1 ATOM 2385 N N . VAL C 3 15 ? 6.761 -30.948 59.381 1.00 60.54 ? 15 VAL C N 1 ATOM 2386 C CA . VAL C 3 15 ? 7.429 -32.107 58.766 1.00 59.70 ? 15 VAL C CA 1 ATOM 2387 C C . VAL C 3 15 ? 6.500 -32.775 57.728 1.00 61.68 ? 15 VAL C C 1 ATOM 2388 O O . VAL C 3 15 ? 5.288 -32.889 57.941 1.00 58.44 ? 15 VAL C O 1 ATOM 2389 C CB . VAL C 3 15 ? 7.902 -33.118 59.848 1.00 57.66 ? 15 VAL C CB 1 ATOM 2390 C CG1 . VAL C 3 15 ? 8.529 -34.374 59.245 1.00 57.46 ? 15 VAL C CG1 1 ATOM 2391 C CG2 . VAL C 3 15 ? 8.903 -32.453 60.785 1.00 58.46 ? 15 VAL C CG2 1 ATOM 2392 N N . GLY C 3 16 ? 7.081 -33.184 56.599 1.00 62.71 ? 16 GLY C N 1 ATOM 2393 C CA . GLY C 3 16 ? 6.326 -33.726 55.474 1.00 65.35 ? 16 GLY C CA 1 ATOM 2394 C C . GLY C 3 16 ? 5.754 -32.714 54.484 1.00 71.09 ? 16 GLY C C 1 ATOM 2395 O O . GLY C 3 16 ? 5.226 -33.121 53.445 1.00 73.55 ? 16 GLY C O 1 ATOM 2396 N N . ASP C 3 17 ? 5.853 -31.411 54.781 1.00 74.75 ? 17 ASP C N 1 ATOM 2397 C CA . ASP C 3 17 ? 5.320 -30.358 53.893 1.00 74.36 ? 17 ASP C CA 1 ATOM 2398 C C . ASP C 3 17 ? 6.172 -30.175 52.636 1.00 74.79 ? 17 ASP C C 1 ATOM 2399 O O . ASP C 3 17 ? 7.396 -30.386 52.657 1.00 68.33 ? 17 ASP C O 1 ATOM 2400 C CB . ASP C 3 17 ? 5.221 -28.998 54.610 1.00 75.87 ? 17 ASP C CB 1 ATOM 2401 C CG . ASP C 3 17 ? 4.086 -28.931 55.624 1.00 76.76 ? 17 ASP C CG 1 ATOM 2402 O OD1 . ASP C 3 17 ? 3.497 -29.982 55.962 1.00 82.31 ? 17 ASP C OD1 1 ATOM 2403 O OD2 . ASP C 3 17 ? 3.788 -27.810 56.090 1.00 73.44 ? 17 ASP C OD2 1 ATOM 2404 N N . ARG C 3 18 ? 5.494 -29.761 51.560 1.00 75.59 ? 18 ARG C N 1 ATOM 2405 C CA . ARG C 3 18 ? 6.106 -29.481 50.265 1.00 75.06 ? 18 ARG C CA 1 ATOM 2406 C C . ARG C 3 18 ? 6.334 -27.973 50.176 1.00 75.14 ? 18 ARG C C 1 ATOM 2407 O O . ARG C 3 18 ? 5.478 -27.234 49.684 1.00 78.75 ? 18 ARG C O 1 ATOM 2408 C CB . ARG C 3 18 ? 5.196 -29.990 49.126 1.00 76.97 ? 18 ARG C CB 1 ATOM 2409 C CG . ARG C 3 18 ? 5.928 -30.419 47.854 1.00 78.81 ? 18 ARG C CG 1 ATOM 2410 C CD . ARG C 3 18 ? 5.026 -30.436 46.624 1.00 77.08 ? 18 ARG C CD 1 ATOM 2411 N NE . ARG C 3 18 ? 5.076 -29.157 45.909 1.00 77.59 ? 18 ARG C NE 1 ATOM 2412 C CZ . ARG C 3 18 ? 5.854 -28.870 44.860 1.00 78.20 ? 18 ARG C CZ 1 ATOM 2413 N NH1 . ARG C 3 18 ? 6.685 -29.772 44.331 1.00 77.20 ? 18 ARG C NH1 1 ATOM 2414 N NH2 . ARG C 3 18 ? 5.795 -27.650 44.321 1.00 77.92 ? 18 ARG C NH2 1 ATOM 2415 N N . VAL C 3 19 ? 7.481 -27.522 50.686 1.00 74.28 ? 19 VAL C N 1 ATOM 2416 C CA . VAL C 3 19 ? 7.848 -26.092 50.654 1.00 72.84 ? 19 VAL C CA 1 ATOM 2417 C C . VAL C 3 19 ? 8.575 -25.716 49.361 1.00 68.89 ? 19 VAL C C 1 ATOM 2418 O O . VAL C 3 19 ? 9.296 -26.534 48.790 1.00 68.21 ? 19 VAL C O 1 ATOM 2419 C CB . VAL C 3 19 ? 8.704 -25.664 51.874 1.00 74.93 ? 19 VAL C CB 1 ATOM 2420 C CG1 . VAL C 3 19 ? 7.944 -25.934 53.164 1.00 76.85 ? 19 VAL C CG1 1 ATOM 2421 C CG2 . VAL C 3 19 ? 10.078 -26.337 51.905 1.00 75.06 ? 19 VAL C CG2 1 ATOM 2422 N N . THR C 3 20 ? 8.374 -24.477 48.914 1.00 64.34 ? 20 THR C N 1 ATOM 2423 C CA . THR C 3 20 ? 9.029 -23.952 47.719 1.00 62.43 ? 20 THR C CA 1 ATOM 2424 C C . THR C 3 20 ? 9.594 -22.547 47.981 1.00 58.45 ? 20 THR C C 1 ATOM 2425 O O . THR C 3 20 ? 8.842 -21.611 48.261 1.00 53.91 ? 20 THR C O 1 ATOM 2426 C CB . THR C 3 20 ? 8.068 -23.913 46.507 1.00 65.08 ? 20 THR C CB 1 ATOM 2427 O OG1 . THR C 3 20 ? 6.975 -23.028 46.774 1.00 68.24 ? 20 THR C OG1 1 ATOM 2428 C CG2 . THR C 3 20 ? 7.520 -25.305 46.194 1.00 66.02 ? 20 THR C CG2 1 ATOM 2429 N N . LEU C 3 21 ? 10.919 -22.418 47.887 1.00 56.56 ? 21 LEU C N 1 ATOM 2430 C CA . LEU C 3 21 ? 11.605 -21.127 47.999 1.00 55.27 ? 21 LEU C CA 1 ATOM 2431 C C . LEU C 3 21 ? 11.732 -20.530 46.606 1.00 53.38 ? 21 LEU C C 1 ATOM 2432 O O . LEU C 3 21 ? 11.873 -21.273 45.643 1.00 50.94 ? 21 LEU C O 1 ATOM 2433 C CB . LEU C 3 21 ? 13.001 -21.293 48.603 1.00 54.93 ? 21 LEU C CB 1 ATOM 2434 C CG . LEU C 3 21 ? 13.167 -22.246 49.787 1.00 54.33 ? 21 LEU C CG 1 ATOM 2435 C CD1 . LEU C 3 21 ? 14.547 -22.064 50.400 1.00 54.11 ? 21 LEU C CD1 1 ATOM 2436 C CD2 . LEU C 3 21 ? 12.075 -22.033 50.821 1.00 54.60 ? 21 LEU C CD2 1 ATOM 2437 N N . THR C 3 22 ? 11.675 -19.201 46.507 1.00 53.50 ? 22 THR C N 1 ATOM 2438 C CA . THR C 3 22 ? 11.854 -18.495 45.229 1.00 55.18 ? 22 THR C CA 1 ATOM 2439 C C . THR C 3 22 ? 13.072 -17.574 45.278 1.00 55.02 ? 22 THR C C 1 ATOM 2440 O O . THR C 3 22 ? 13.563 -17.216 46.348 1.00 56.31 ? 22 THR C O 1 ATOM 2441 C CB . THR C 3 22 ? 10.619 -17.655 44.832 1.00 55.08 ? 22 THR C CB 1 ATOM 2442 O OG1 . THR C 3 22 ? 10.308 -16.743 45.883 1.00 59.58 ? 22 THR C OG1 1 ATOM 2443 C CG2 . THR C 3 22 ? 9.406 -18.533 44.556 1.00 53.93 ? 22 THR C CG2 1 ATOM 2444 N N . CYS C 3 23 ? 13.550 -17.199 44.099 1.00 55.85 ? 23 CYS C N 1 ATOM 2445 C CA . CYS C 3 23 ? 14.741 -16.375 43.969 1.00 56.03 ? 23 CYS C CA 1 ATOM 2446 C C . CYS C 3 23 ? 14.681 -15.680 42.616 1.00 55.70 ? 23 CYS C C 1 ATOM 2447 O O . CYS C 3 23 ? 15.001 -16.276 41.594 1.00 54.46 ? 23 CYS C O 1 ATOM 2448 C CB . CYS C 3 23 ? 15.990 -17.251 44.132 1.00 57.43 ? 23 CYS C CB 1 ATOM 2449 S SG . CYS C 3 23 ? 17.596 -16.432 43.973 1.00 57.62 ? 23 CYS C SG 1 ATOM 2450 N N . LYS C 3 24 ? 14.223 -14.425 42.634 1.00 60.43 ? 24 LYS C N 1 ATOM 2451 C CA . LYS C 3 24 ? 14.050 -13.595 41.432 1.00 62.34 ? 24 LYS C CA 1 ATOM 2452 C C . LYS C 3 24 ? 15.246 -12.662 41.265 1.00 63.78 ? 24 LYS C C 1 ATOM 2453 O O . LYS C 3 24 ? 15.743 -12.095 42.252 1.00 68.57 ? 24 LYS C O 1 ATOM 2454 C CB . LYS C 3 24 ? 12.762 -12.768 41.522 1.00 62.75 ? 24 LYS C CB 1 ATOM 2455 C CG . LYS C 3 24 ? 11.576 -13.560 42.053 1.00 67.76 ? 24 LYS C CG 1 ATOM 2456 C CD . LYS C 3 24 ? 10.227 -12.931 41.732 1.00 70.17 ? 24 LYS C CD 1 ATOM 2457 C CE . LYS C 3 24 ? 9.104 -13.708 42.411 1.00 71.06 ? 24 LYS C CE 1 ATOM 2458 N NZ . LYS C 3 24 ? 7.758 -13.371 41.873 1.00 71.92 ? 24 LYS C NZ 1 ATOM 2459 N N . GLY C 3 25 ? 15.701 -12.509 40.021 1.00 60.68 ? 25 GLY C N 1 ATOM 2460 C CA . GLY C 3 25 ? 16.855 -11.669 39.698 1.00 57.26 ? 25 GLY C CA 1 ATOM 2461 C C . GLY C 3 25 ? 16.458 -10.352 39.069 1.00 55.34 ? 25 GLY C C 1 ATOM 2462 O O . GLY C 3 25 ? 15.434 -10.266 38.399 1.00 53.44 ? 25 GLY C O 1 ATOM 2463 N N . SER C 3 26 ? 17.282 -9.328 39.279 1.00 58.70 ? 26 SER C N 1 ATOM 2464 C CA . SER C 3 26 ? 17.083 -8.005 38.656 1.00 59.91 ? 26 SER C CA 1 ATOM 2465 C C . SER C 3 26 ? 17.275 -8.029 37.136 1.00 61.13 ? 26 SER C C 1 ATOM 2466 O O . SER C 3 26 ? 16.627 -7.267 36.428 1.00 61.18 ? 26 SER C O 1 ATOM 2467 C CB . SER C 3 26 ? 18.006 -6.955 39.298 1.00 59.24 ? 26 SER C CB 1 ATOM 2468 O OG . SER C 3 26 ? 19.292 -7.488 39.574 1.00 58.62 ? 26 SER C OG 1 ATOM 2469 N N . GLN C 3 27 ? 18.161 -8.907 36.656 1.00 67.79 ? 27 GLN C N 1 ATOM 2470 C CA . GLN C 3 27 ? 18.385 -9.148 35.215 1.00 70.86 ? 27 GLN C CA 1 ATOM 2471 C C . GLN C 3 27 ? 18.333 -10.650 34.893 1.00 68.79 ? 27 GLN C C 1 ATOM 2472 O O . GLN C 3 27 ? 18.226 -11.483 35.800 1.00 69.68 ? 27 GLN C O 1 ATOM 2473 C CB . GLN C 3 27 ? 19.742 -8.586 34.786 1.00 72.68 ? 27 GLN C CB 1 ATOM 2474 C CG . GLN C 3 27 ? 19.973 -7.134 35.170 1.00 75.90 ? 27 GLN C CG 1 ATOM 2475 C CD . GLN C 3 27 ? 21.365 -6.673 34.803 1.00 80.02 ? 27 GLN C CD 1 ATOM 2476 O OE1 . GLN C 3 27 ? 21.797 -6.828 33.659 1.00 80.56 ? 27 GLN C OE1 1 ATOM 2477 N NE2 . GLN C 3 27 ? 22.080 -6.108 35.773 1.00 84.11 ? 27 GLN C NE2 1 ATOM 2478 N N . ASN C 3 28 ? 18.411 -10.983 33.603 1.00 65.13 ? 28 ASN C N 1 ATOM 2479 C CA . ASN C 3 28 ? 18.462 -12.380 33.148 1.00 62.88 ? 28 ASN C CA 1 ATOM 2480 C C . ASN C 3 28 ? 19.712 -13.092 33.697 1.00 62.79 ? 28 ASN C C 1 ATOM 2481 O O . ASN C 3 28 ? 20.828 -12.579 33.584 1.00 63.34 ? 28 ASN C O 1 ATOM 2482 C CB . ASN C 3 28 ? 18.434 -12.442 31.615 1.00 61.60 ? 28 ASN C CB 1 ATOM 2483 C CG . ASN C 3 28 ? 18.539 -13.858 31.070 1.00 63.01 ? 28 ASN C CG 1 ATOM 2484 O OD1 . ASN C 3 28 ? 18.454 -14.842 31.808 1.00 62.03 ? 28 ASN C OD1 1 ATOM 2485 N ND2 . ASN C 3 28 ? 18.730 -13.966 29.758 1.00 63.42 ? 28 ASN C ND2 1 ATOM 2486 N N . ILE C 3 29 ? 19.497 -14.261 34.307 1.00 63.40 ? 29 ILE C N 1 ATOM 2487 C CA . ILE C 3 29 ? 20.564 -15.069 34.929 1.00 62.62 ? 29 ILE C CA 1 ATOM 2488 C C . ILE C 3 29 ? 20.982 -16.250 34.034 1.00 61.81 ? 29 ILE C C 1 ATOM 2489 O O . ILE C 3 29 ? 22.080 -16.793 34.200 1.00 60.97 ? 29 ILE C O 1 ATOM 2490 C CB . ILE C 3 29 ? 20.149 -15.555 36.347 1.00 62.08 ? 29 ILE C CB 1 ATOM 2491 C CG1 . ILE C 3 29 ? 19.860 -14.345 37.249 1.00 63.86 ? 29 ILE C CG1 1 ATOM 2492 C CG2 . ILE C 3 29 ? 21.245 -16.411 36.983 1.00 62.47 ? 29 ILE C CG2 1 ATOM 2493 C CD1 . ILE C 3 29 ? 19.149 -14.663 38.549 1.00 65.55 ? 29 ILE C CD1 1 ATOM 2494 N N . ASP C 3 30 ? 20.114 -16.646 33.097 1.00 59.72 ? 30 ASP C N 1 ATOM 2495 C CA . ASP C 3 30 ? 20.456 -17.619 32.059 1.00 58.99 ? 30 ASP C CA 1 ATOM 2496 C C . ASP C 3 30 ? 20.856 -18.992 32.649 1.00 55.67 ? 30 ASP C C 1 ATOM 2497 O O . ASP C 3 30 ? 21.787 -19.645 32.176 1.00 56.76 ? 30 ASP C O 1 ATOM 2498 C CB . ASP C 3 30 ? 21.559 -17.027 31.156 1.00 60.89 ? 30 ASP C CB 1 ATOM 2499 C CG . ASP C 3 30 ? 21.638 -17.685 29.787 1.00 63.88 ? 30 ASP C CG 1 ATOM 2500 O OD1 . ASP C 3 30 ? 20.808 -18.563 29.464 1.00 67.65 ? 30 ASP C OD1 1 ATOM 2501 O OD2 . ASP C 3 30 ? 22.556 -17.313 29.025 1.00 67.16 ? 30 ASP C OD2 1 ATOM 2502 N N . ASN C 3 31 ? 20.138 -19.401 33.696 1.00 50.83 ? 31 ASN C N 1 ATOM 2503 C CA . ASN C 3 31 ? 20.296 -20.700 34.370 1.00 48.36 ? 31 ASN C CA 1 ATOM 2504 C C . ASN C 3 31 ? 21.561 -20.916 35.207 1.00 46.81 ? 31 ASN C C 1 ATOM 2505 O O . ASN C 3 31 ? 21.713 -21.976 35.810 1.00 46.65 ? 31 ASN C O 1 ATOM 2506 C CB . ASN C 3 31 ? 20.101 -21.878 33.395 1.00 49.12 ? 31 ASN C CB 1 ATOM 2507 C CG . ASN C 3 31 ? 18.657 -22.062 32.993 1.00 51.28 ? 31 ASN C CG 1 ATOM 2508 O OD1 . ASN C 3 31 ? 18.221 -21.572 31.948 1.00 54.21 ? 31 ASN C OD1 1 ATOM 2509 N ND2 . ASN C 3 31 ? 17.895 -22.758 33.832 1.00 51.80 ? 31 ASN C ND2 1 ATOM 2510 N N . TYR C 3 32 ? 22.442 -19.923 35.285 1.00 46.54 ? 32 TYR C N 1 ATOM 2511 C CA . TYR C 3 32 ? 23.657 -20.043 36.088 1.00 47.34 ? 32 TYR C CA 1 ATOM 2512 C C . TYR C 3 32 ? 23.336 -19.591 37.514 1.00 47.69 ? 32 TYR C C 1 ATOM 2513 O O . TYR C 3 32 ? 23.633 -18.456 37.915 1.00 44.63 ? 32 TYR C O 1 ATOM 2514 C CB . TYR C 3 32 ? 24.789 -19.210 35.488 1.00 48.10 ? 32 TYR C CB 1 ATOM 2515 C CG . TYR C 3 32 ? 25.312 -19.703 34.149 1.00 48.86 ? 32 TYR C CG 1 ATOM 2516 C CD1 . TYR C 3 32 ? 24.710 -19.306 32.956 1.00 48.30 ? 32 TYR C CD1 1 ATOM 2517 C CD2 . TYR C 3 32 ? 26.426 -20.545 34.075 1.00 48.66 ? 32 TYR C CD2 1 ATOM 2518 C CE1 . TYR C 3 32 ? 25.183 -19.749 31.730 1.00 48.86 ? 32 TYR C CE1 1 ATOM 2519 C CE2 . TYR C 3 32 ? 26.913 -20.987 32.853 1.00 49.03 ? 32 TYR C CE2 1 ATOM 2520 C CZ . TYR C 3 32 ? 26.291 -20.586 31.684 1.00 48.80 ? 32 TYR C CZ 1 ATOM 2521 O OH . TYR C 3 32 ? 26.771 -21.028 30.474 1.00 48.68 ? 32 TYR C OH 1 ATOM 2522 N N . LEU C 3 33 ? 22.709 -20.495 38.264 1.00 47.35 ? 33 LEU C N 1 ATOM 2523 C CA . LEU C 3 33 ? 22.240 -20.204 39.611 1.00 45.59 ? 33 LEU C CA 1 ATOM 2524 C C . LEU C 3 33 ? 22.342 -21.429 40.513 1.00 45.22 ? 33 LEU C C 1 ATOM 2525 O O . LEU C 3 33 ? 21.919 -22.526 40.134 1.00 44.41 ? 33 LEU C O 1 ATOM 2526 C CB . LEU C 3 33 ? 20.804 -19.703 39.554 1.00 46.47 ? 33 LEU C CB 1 ATOM 2527 C CG . LEU C 3 33 ? 20.186 -19.335 40.910 1.00 48.79 ? 33 LEU C CG 1 ATOM 2528 C CD1 . LEU C 3 33 ? 19.545 -17.953 40.875 1.00 50.78 ? 33 LEU C CD1 1 ATOM 2529 C CD2 . LEU C 3 33 ? 19.183 -20.388 41.361 1.00 47.91 ? 33 LEU C CD2 1 ATOM 2530 N N . ALA C 3 34 ? 22.903 -21.223 41.705 1.00 45.27 ? 34 ALA C N 1 ATOM 2531 C CA . ALA C 3 34 ? 23.128 -22.295 42.679 1.00 44.91 ? 34 ALA C CA 1 ATOM 2532 C C . ALA C 3 34 ? 22.327 -22.055 43.950 1.00 44.23 ? 34 ALA C C 1 ATOM 2533 O O . ALA C 3 34 ? 21.854 -20.946 44.182 1.00 44.10 ? 34 ALA C O 1 ATOM 2534 C CB . ALA C 3 34 ? 24.609 -22.406 43.003 1.00 44.47 ? 34 ALA C CB 1 ATOM 2535 N N . TRP C 3 35 ? 22.165 -23.112 44.747 1.00 43.78 ? 35 TRP C N 1 ATOM 2536 C CA . TRP C 3 35 ? 21.517 -23.040 46.066 1.00 45.19 ? 35 TRP C CA 1 ATOM 2537 C C . TRP C 3 35 ? 22.405 -23.738 47.103 1.00 48.23 ? 35 TRP C C 1 ATOM 2538 O O . TRP C 3 35 ? 22.914 -24.831 46.841 1.00 47.42 ? 35 TRP C O 1 ATOM 2539 C CB . TRP C 3 35 ? 20.147 -23.728 46.059 1.00 42.15 ? 35 TRP C CB 1 ATOM 2540 C CG . TRP C 3 35 ? 19.107 -23.085 45.217 1.00 40.81 ? 35 TRP C CG 1 ATOM 2541 C CD1 . TRP C 3 35 ? 18.881 -23.305 43.887 1.00 41.31 ? 35 TRP C CD1 1 ATOM 2542 C CD2 . TRP C 3 35 ? 18.115 -22.145 45.641 1.00 40.49 ? 35 TRP C CD2 1 ATOM 2543 N NE1 . TRP C 3 35 ? 17.819 -22.551 43.454 1.00 40.05 ? 35 TRP C NE1 1 ATOM 2544 C CE2 . TRP C 3 35 ? 17.330 -21.826 44.509 1.00 40.19 ? 35 TRP C CE2 1 ATOM 2545 C CE3 . TRP C 3 35 ? 17.814 -21.534 46.868 1.00 41.23 ? 35 TRP C CE3 1 ATOM 2546 C CZ2 . TRP C 3 35 ? 16.264 -20.913 44.564 1.00 40.03 ? 35 TRP C CZ2 1 ATOM 2547 C CZ3 . TRP C 3 35 ? 16.749 -20.625 46.923 1.00 39.86 ? 35 TRP C CZ3 1 ATOM 2548 C CH2 . TRP C 3 35 ? 15.989 -20.330 45.776 1.00 39.85 ? 35 TRP C CH2 1 ATOM 2549 N N . TYR C 3 36 ? 22.588 -23.117 48.270 1.00 51.64 ? 36 TYR C N 1 ATOM 2550 C CA . TYR C 3 36 ? 23.286 -23.768 49.379 1.00 55.57 ? 36 TYR C CA 1 ATOM 2551 C C . TYR C 3 36 ? 22.552 -23.636 50.719 1.00 58.85 ? 36 TYR C C 1 ATOM 2552 O O . TYR C 3 36 ? 21.778 -22.695 50.946 1.00 57.56 ? 36 TYR C O 1 ATOM 2553 C CB . TYR C 3 36 ? 24.748 -23.298 49.480 1.00 57.18 ? 36 TYR C CB 1 ATOM 2554 C CG . TYR C 3 36 ? 24.975 -21.887 49.989 1.00 58.74 ? 36 TYR C CG 1 ATOM 2555 C CD1 . TYR C 3 36 ? 25.018 -21.614 51.358 1.00 59.69 ? 36 TYR C CD1 1 ATOM 2556 C CD2 . TYR C 3 36 ? 25.197 -20.834 49.107 1.00 60.22 ? 36 TYR C CD2 1 ATOM 2557 C CE1 . TYR C 3 36 ? 25.245 -20.329 51.832 1.00 59.45 ? 36 TYR C CE1 1 ATOM 2558 C CE2 . TYR C 3 36 ? 25.427 -19.544 49.572 1.00 61.35 ? 36 TYR C CE2 1 ATOM 2559 C CZ . TYR C 3 36 ? 25.455 -19.300 50.935 1.00 59.97 ? 36 TYR C CZ 1 ATOM 2560 O OH . TYR C 3 36 ? 25.679 -18.029 51.400 1.00 61.69 ? 36 TYR C OH 1 ATOM 2561 N N . GLN C 3 37 ? 22.824 -24.603 51.590 1.00 62.24 ? 37 GLN C N 1 ATOM 2562 C CA . GLN C 3 37 ? 22.186 -24.742 52.892 1.00 65.61 ? 37 GLN C CA 1 ATOM 2563 C C . GLN C 3 37 ? 23.201 -24.314 53.938 1.00 68.34 ? 37 GLN C C 1 ATOM 2564 O O . GLN C 3 37 ? 24.341 -24.776 53.909 1.00 68.74 ? 37 GLN C O 1 ATOM 2565 C CB . GLN C 3 37 ? 21.801 -26.211 53.096 1.00 66.14 ? 37 GLN C CB 1 ATOM 2566 C CG . GLN C 3 37 ? 21.096 -26.563 54.397 1.00 65.84 ? 37 GLN C CG 1 ATOM 2567 C CD . GLN C 3 37 ? 20.825 -28.054 54.503 1.00 65.00 ? 37 GLN C CD 1 ATOM 2568 O OE1 . GLN C 3 37 ? 21.736 -28.871 54.367 1.00 61.76 ? 37 GLN C OE1 1 ATOM 2569 N NE2 . GLN C 3 37 ? 19.569 -28.417 54.747 1.00 66.83 ? 37 GLN C NE2 1 ATOM 2570 N N . GLN C 3 38 ? 22.794 -23.439 54.854 1.00 72.85 ? 38 GLN C N 1 ATOM 2571 C CA . GLN C 3 38 ? 23.668 -23.009 55.947 1.00 77.63 ? 38 GLN C CA 1 ATOM 2572 C C . GLN C 3 38 ? 22.991 -23.226 57.298 1.00 77.29 ? 38 GLN C C 1 ATOM 2573 O O . GLN C 3 38 ? 22.139 -22.441 57.719 1.00 74.77 ? 38 GLN C O 1 ATOM 2574 C CB . GLN C 3 38 ? 24.077 -21.543 55.767 1.00 81.26 ? 38 GLN C CB 1 ATOM 2575 C CG . GLN C 3 38 ? 25.146 -21.067 56.745 1.00 81.76 ? 38 GLN C CG 1 ATOM 2576 C CD . GLN C 3 38 ? 25.779 -19.751 56.330 1.00 83.56 ? 38 GLN C CD 1 ATOM 2577 O OE1 . GLN C 3 38 ? 25.148 -18.912 55.680 1.00 82.63 ? 38 GLN C OE1 1 ATOM 2578 N NE2 . GLN C 3 38 ? 27.038 -19.565 56.703 1.00 85.83 ? 38 GLN C NE2 1 ATOM 2579 N N . LYS C 3 39 ? 23.366 -24.318 57.956 1.00 80.00 ? 39 LYS C N 1 ATOM 2580 C CA . LYS C 3 39 ? 23.013 -24.543 59.355 1.00 84.90 ? 39 LYS C CA 1 ATOM 2581 C C . LYS C 3 39 ? 23.932 -23.698 60.235 1.00 88.24 ? 39 LYS C C 1 ATOM 2582 O O . LYS C 3 39 ? 25.033 -23.332 59.817 1.00 91.27 ? 39 LYS C O 1 ATOM 2583 C CB . LYS C 3 39 ? 23.131 -26.024 59.715 1.00 85.77 ? 39 LYS C CB 1 ATOM 2584 C CG . LYS C 3 39 ? 22.094 -26.905 59.035 1.00 85.24 ? 39 LYS C CG 1 ATOM 2585 C CD . LYS C 3 39 ? 22.429 -28.378 59.202 1.00 86.84 ? 39 LYS C CD 1 ATOM 2586 C CE . LYS C 3 39 ? 21.393 -29.254 58.528 1.00 87.50 ? 39 LYS C CE 1 ATOM 2587 N NZ . LYS C 3 39 ? 21.740 -30.699 58.583 1.00 86.64 ? 39 LYS C NZ 1 ATOM 2588 N N . LEU C 3 40 ? 23.480 -23.403 61.453 1.00 92.53 ? 40 LEU C N 1 ATOM 2589 C CA . LEU C 3 40 ? 24.195 -22.478 62.341 1.00 92.53 ? 40 LEU C CA 1 ATOM 2590 C C . LEU C 3 40 ? 25.487 -23.110 62.880 1.00 88.57 ? 40 LEU C C 1 ATOM 2591 O O . LEU C 3 40 ? 25.481 -24.250 63.358 1.00 81.27 ? 40 LEU C O 1 ATOM 2592 C CB . LEU C 3 40 ? 23.295 -22.011 63.497 1.00 94.79 ? 40 LEU C CB 1 ATOM 2593 C CG . LEU C 3 40 ? 23.636 -20.633 64.086 1.00 94.51 ? 40 LEU C CG 1 ATOM 2594 C CD1 . LEU C 3 40 ? 23.107 -19.520 63.188 1.00 93.38 ? 40 LEU C CD1 1 ATOM 2595 C CD2 . LEU C 3 40 ? 23.093 -20.491 65.505 1.00 93.56 ? 40 LEU C CD2 1 ATOM 2596 N N . GLY C 3 41 ? 26.585 -22.358 62.776 1.00 86.56 ? 41 GLY C N 1 ATOM 2597 C CA . GLY C 3 41 ? 27.907 -22.818 63.193 1.00 85.64 ? 41 GLY C CA 1 ATOM 2598 C C . GLY C 3 41 ? 28.466 -23.999 62.417 1.00 85.49 ? 41 GLY C C 1 ATOM 2599 O O . GLY C 3 41 ? 29.300 -24.732 62.946 1.00 87.67 ? 41 GLY C O 1 ATOM 2600 N N . GLU C 3 42 ? 28.017 -24.182 61.172 1.00 83.87 ? 42 GLU C N 1 ATOM 2601 C CA . GLU C 3 42 ? 28.478 -25.277 60.310 1.00 83.77 ? 42 GLU C CA 1 ATOM 2602 C C . GLU C 3 42 ? 28.889 -24.746 58.948 1.00 78.80 ? 42 GLU C C 1 ATOM 2603 O O . GLU C 3 42 ? 28.458 -23.664 58.548 1.00 81.44 ? 42 GLU C O 1 ATOM 2604 C CB . GLU C 3 42 ? 27.374 -26.311 60.133 1.00 88.31 ? 42 GLU C CB 1 ATOM 2605 C CG . GLU C 3 42 ? 27.033 -27.063 61.405 1.00 94.13 ? 42 GLU C CG 1 ATOM 2606 C CD . GLU C 3 42 ? 26.393 -28.410 61.130 1.00 98.83 ? 42 GLU C CD 1 ATOM 2607 O OE1 . GLU C 3 42 ? 25.429 -28.464 60.335 1.00 100.14 ? 42 GLU C OE1 1 ATOM 2608 O OE2 . GLU C 3 42 ? 26.856 -29.416 61.711 1.00 102.46 ? 42 GLU C OE2 1 ATOM 2609 N N . ALA C 3 43 ? 29.718 -25.511 58.238 1.00 72.27 ? 43 ALA C N 1 ATOM 2610 C CA . ALA C 3 43 ? 30.147 -25.136 56.886 1.00 69.36 ? 43 ALA C CA 1 ATOM 2611 C C . ALA C 3 43 ? 28.956 -25.215 55.920 1.00 65.71 ? 43 ALA C C 1 ATOM 2612 O O . ALA C 3 43 ? 28.248 -26.230 55.912 1.00 63.14 ? 43 ALA C O 1 ATOM 2613 C CB . ALA C 3 43 ? 31.270 -26.045 56.409 1.00 69.13 ? 43 ALA C CB 1 ATOM 2614 N N . PRO C 3 44 ? 28.710 -24.143 55.128 1.00 62.38 ? 44 PRO C N 1 ATOM 2615 C CA . PRO C 3 44 ? 27.643 -24.190 54.117 1.00 61.11 ? 44 PRO C CA 1 ATOM 2616 C C . PRO C 3 44 ? 27.790 -25.358 53.140 1.00 60.16 ? 44 PRO C C 1 ATOM 2617 O O . PRO C 3 44 ? 28.910 -25.726 52.779 1.00 59.74 ? 44 PRO C O 1 ATOM 2618 C CB . PRO C 3 44 ? 27.788 -22.854 53.383 1.00 60.00 ? 44 PRO C CB 1 ATOM 2619 C CG . PRO C 3 44 ? 28.373 -21.934 54.389 1.00 60.66 ? 44 PRO C CG 1 ATOM 2620 C CD . PRO C 3 44 ? 29.264 -22.780 55.262 1.00 62.50 ? 44 PRO C CD 1 ATOM 2621 N N . LYS C 3 45 ? 26.662 -25.942 52.744 1.00 60.50 ? 45 LYS C N 1 ATOM 2622 C CA . LYS C 3 45 ? 26.643 -27.116 51.864 1.00 61.68 ? 45 LYS C CA 1 ATOM 2623 C C . LYS C 3 45 ? 25.884 -26.801 50.571 1.00 58.75 ? 45 LYS C C 1 ATOM 2624 O O . LYS C 3 45 ? 24.739 -26.341 50.614 1.00 56.76 ? 45 LYS C O 1 ATOM 2625 C CB . LYS C 3 45 ? 25.998 -28.303 52.584 1.00 64.56 ? 45 LYS C CB 1 ATOM 2626 C CG . LYS C 3 45 ? 26.004 -29.601 51.789 1.00 67.59 ? 45 LYS C CG 1 ATOM 2627 C CD . LYS C 3 45 ? 25.573 -30.786 52.638 1.00 69.72 ? 45 LYS C CD 1 ATOM 2628 C CE . LYS C 3 45 ? 26.724 -31.337 53.462 1.00 71.81 ? 45 LYS C CE 1 ATOM 2629 N NZ . LYS C 3 45 ? 26.276 -32.499 54.277 1.00 74.89 ? 45 LYS C NZ 1 ATOM 2630 N N . LEU C 3 46 ? 26.526 -27.057 49.431 1.00 53.88 ? 46 LEU C N 1 ATOM 2631 C CA . LEU C 3 46 ? 25.911 -26.830 48.126 1.00 51.49 ? 46 LEU C CA 1 ATOM 2632 C C . LEU C 3 46 ? 24.836 -27.885 47.861 1.00 48.40 ? 46 LEU C C 1 ATOM 2633 O O . LEU C 3 46 ? 25.093 -29.087 47.976 1.00 47.31 ? 46 LEU C O 1 ATOM 2634 C CB . LEU C 3 46 ? 26.973 -26.885 47.026 1.00 51.62 ? 46 LEU C CB 1 ATOM 2635 C CG . LEU C 3 46 ? 26.526 -26.532 45.605 1.00 52.21 ? 46 LEU C CG 1 ATOM 2636 C CD1 . LEU C 3 46 ? 26.198 -25.047 45.496 1.00 52.93 ? 46 LEU C CD1 1 ATOM 2637 C CD2 . LEU C 3 46 ? 27.588 -26.922 44.585 1.00 53.57 ? 46 LEU C CD2 1 ATOM 2638 N N . LEU C 3 47 ? 23.637 -27.424 47.514 1.00 46.47 ? 47 LEU C N 1 ATOM 2639 C CA . LEU C 3 47 ? 22.523 -28.306 47.180 1.00 47.25 ? 47 LEU C CA 1 ATOM 2640 C C . LEU C 3 47 ? 22.451 -28.457 45.666 1.00 47.32 ? 47 LEU C C 1 ATOM 2641 O O . LEU C 3 47 ? 22.630 -29.552 45.134 1.00 48.56 ? 47 LEU C O 1 ATOM 2642 C CB . LEU C 3 47 ? 21.197 -27.751 47.724 1.00 47.21 ? 47 LEU C CB 1 ATOM 2643 C CG . LEU C 3 47 ? 21.118 -27.422 49.222 1.00 45.33 ? 47 LEU C CG 1 ATOM 2644 C CD1 . LEU C 3 47 ? 19.782 -26.778 49.570 1.00 43.90 ? 47 LEU C CD1 1 ATOM 2645 C CD2 . LEU C 3 47 ? 21.354 -28.666 50.063 1.00 44.72 ? 47 LEU C CD2 1 ATOM 2646 N N . ILE C 3 48 ? 22.229 -27.341 44.980 1.00 46.73 ? 48 ILE C N 1 ATOM 2647 C CA . ILE C 3 48 ? 21.993 -27.331 43.545 1.00 46.91 ? 48 ILE C CA 1 ATOM 2648 C C . ILE C 3 48 ? 22.904 -26.322 42.842 1.00 44.26 ? 48 ILE C C 1 ATOM 2649 O O . ILE C 3 48 ? 23.262 -25.298 43.413 1.00 43.43 ? 48 ILE C O 1 ATOM 2650 C CB . ILE C 3 48 ? 20.487 -27.082 43.274 1.00 48.53 ? 48 ILE C CB 1 ATOM 2651 C CG1 . ILE C 3 48 ? 19.727 -28.404 43.449 1.00 50.04 ? 48 ILE C CG1 1 ATOM 2652 C CG2 . ILE C 3 48 ? 20.225 -26.540 41.871 1.00 49.20 ? 48 ILE C CG2 1 ATOM 2653 C CD1 . ILE C 3 48 ? 18.266 -28.246 43.786 1.00 51.01 ? 48 ILE C CD1 1 ATOM 2654 N N . TYR C 3 49 ? 23.288 -26.652 41.612 1.00 43.20 ? 49 TYR C N 1 ATOM 2655 C CA . TYR C 3 49 ? 24.016 -25.742 40.720 1.00 42.83 ? 49 TYR C CA 1 ATOM 2656 C C . TYR C 3 49 ? 23.440 -25.855 39.310 1.00 41.48 ? 49 TYR C C 1 ATOM 2657 O O . TYR C 3 49 ? 22.692 -26.788 39.010 1.00 40.13 ? 49 TYR C O 1 ATOM 2658 C CB . TYR C 3 49 ? 25.523 -26.035 40.733 1.00 42.38 ? 49 TYR C CB 1 ATOM 2659 C CG . TYR C 3 49 ? 25.914 -27.354 40.109 1.00 42.49 ? 49 TYR C CG 1 ATOM 2660 C CD1 . TYR C 3 49 ? 25.657 -28.555 40.758 1.00 42.77 ? 49 TYR C CD1 1 ATOM 2661 C CD2 . TYR C 3 49 ? 26.545 -27.404 38.870 1.00 42.82 ? 49 TYR C CD2 1 ATOM 2662 C CE1 . TYR C 3 49 ? 26.012 -29.767 40.190 1.00 42.44 ? 49 TYR C CE1 1 ATOM 2663 C CE2 . TYR C 3 49 ? 26.907 -28.614 38.298 1.00 42.12 ? 49 TYR C CE2 1 ATOM 2664 C CZ . TYR C 3 49 ? 26.635 -29.790 38.965 1.00 41.71 ? 49 TYR C CZ 1 ATOM 2665 O OH . TYR C 3 49 ? 26.986 -30.994 38.416 1.00 42.60 ? 49 TYR C OH 1 ATOM 2666 N N . LYS C 3 50 ? 23.791 -24.894 38.463 1.00 40.46 ? 50 LYS C N 1 ATOM 2667 C CA . LYS C 3 50 ? 23.161 -24.708 37.151 1.00 41.58 ? 50 LYS C CA 1 ATOM 2668 C C . LYS C 3 50 ? 21.640 -24.942 37.165 1.00 41.05 ? 50 LYS C C 1 ATOM 2669 O O . LYS C 3 50 ? 21.131 -25.815 36.463 1.00 41.37 ? 50 LYS C O 1 ATOM 2670 C CB . LYS C 3 50 ? 23.846 -25.588 36.100 1.00 43.09 ? 50 LYS C CB 1 ATOM 2671 C CG . LYS C 3 50 ? 23.602 -25.147 34.659 1.00 44.47 ? 50 LYS C CG 1 ATOM 2672 C CD . LYS C 3 50 ? 24.462 -23.947 34.279 1.00 46.41 ? 50 LYS C CD 1 ATOM 2673 C CE . LYS C 3 50 ? 23.929 -23.238 33.045 1.00 47.75 ? 50 LYS C CE 1 ATOM 2674 N NZ . LYS C 3 50 ? 23.998 -24.111 31.837 1.00 49.36 ? 50 LYS C NZ 1 ATOM 2675 N N . THR C 3 51 ? 20.937 -24.183 38.005 1.00 40.55 ? 51 THR C N 1 ATOM 2676 C CA . THR C 3 51 ? 19.468 -24.241 38.147 1.00 41.48 ? 51 THR C CA 1 ATOM 2677 C C . THR C 3 51 ? 18.890 -25.526 38.753 1.00 42.78 ? 51 THR C C 1 ATOM 2678 O O . THR C 3 51 ? 18.089 -25.430 39.687 1.00 41.74 ? 51 THR C O 1 ATOM 2679 C CB . THR C 3 51 ? 18.727 -23.941 36.823 1.00 41.87 ? 51 THR C CB 1 ATOM 2680 O OG1 . THR C 3 51 ? 19.071 -22.627 36.385 1.00 42.56 ? 51 THR C OG1 1 ATOM 2681 C CG2 . THR C 3 51 ? 17.200 -24.018 36.996 1.00 41.91 ? 51 THR C CG2 1 ATOM 2682 N N . ASN C 3 52 ? 19.239 -26.696 38.202 1.00 43.10 ? 52 ASN C N 1 ATOM 2683 C CA . ASN C 3 52 ? 18.626 -27.972 38.611 1.00 42.38 ? 52 ASN C CA 1 ATOM 2684 C C . ASN C 3 52 ? 19.547 -29.209 38.726 1.00 43.37 ? 52 ASN C C 1 ATOM 2685 O O . ASN C 3 52 ? 19.040 -30.316 38.914 1.00 44.69 ? 52 ASN C O 1 ATOM 2686 C CB . ASN C 3 52 ? 17.445 -28.283 37.672 1.00 41.81 ? 52 ASN C CB 1 ATOM 2687 C CG . ASN C 3 52 ? 17.859 -28.416 36.212 1.00 40.77 ? 52 ASN C CG 1 ATOM 2688 O OD1 . ASN C 3 52 ? 19.014 -28.680 35.894 1.00 40.56 ? 52 ASN C OD1 1 ATOM 2689 N ND2 . ASN C 3 52 ? 16.905 -28.231 35.319 1.00 39.20 ? 52 ASN C ND2 1 ATOM 2690 N N . SER C 3 53 ? 20.869 -29.052 38.628 1.00 44.30 ? 53 SER C N 1 ATOM 2691 C CA . SER C 3 53 ? 21.772 -30.196 38.816 1.00 45.42 ? 53 SER C CA 1 ATOM 2692 C C . SER C 3 53 ? 21.915 -30.446 40.305 1.00 47.47 ? 53 SER C C 1 ATOM 2693 O O . SER C 3 53 ? 22.366 -29.561 41.038 1.00 46.56 ? 53 SER C O 1 ATOM 2694 C CB . SER C 3 53 ? 23.160 -29.955 38.213 1.00 45.40 ? 53 SER C CB 1 ATOM 2695 O OG . SER C 3 53 ? 23.112 -29.872 36.805 1.00 45.16 ? 53 SER C OG 1 ATOM 2696 N N . LEU C 3 54 ? 21.525 -31.640 40.747 1.00 49.90 ? 54 LEU C N 1 ATOM 2697 C CA . LEU C 3 54 ? 21.651 -32.028 42.151 1.00 51.81 ? 54 LEU C CA 1 ATOM 2698 C C . LEU C 3 54 ? 23.106 -32.356 42.445 1.00 52.25 ? 54 LEU C C 1 ATOM 2699 O O . LEU C 3 54 ? 23.734 -33.097 41.697 1.00 53.36 ? 54 LEU C O 1 ATOM 2700 C CB . LEU C 3 54 ? 20.769 -33.240 42.443 1.00 53.51 ? 54 LEU C CB 1 ATOM 2701 C CG . LEU C 3 54 ? 20.665 -33.721 43.893 1.00 56.17 ? 54 LEU C CG 1 ATOM 2702 C CD1 . LEU C 3 54 ? 20.009 -32.664 44.770 1.00 57.70 ? 54 LEU C CD1 1 ATOM 2703 C CD2 . LEU C 3 54 ? 19.894 -35.034 43.957 1.00 55.88 ? 54 LEU C CD2 1 ATOM 2704 N N . GLN C 3 55 ? 23.639 -31.793 43.524 1.00 55.40 ? 55 GLN C N 1 ATOM 2705 C CA . GLN C 3 55 ? 25.019 -32.049 43.939 1.00 59.77 ? 55 GLN C CA 1 ATOM 2706 C C . GLN C 3 55 ? 25.112 -33.487 44.441 1.00 62.23 ? 55 GLN C C 1 ATOM 2707 O O . GLN C 3 55 ? 24.156 -34.003 45.020 1.00 65.05 ? 55 GLN C O 1 ATOM 2708 C CB . GLN C 3 55 ? 25.434 -31.053 45.034 1.00 60.89 ? 55 GLN C CB 1 ATOM 2709 C CG . GLN C 3 55 ? 26.866 -31.167 45.563 1.00 61.92 ? 55 GLN C CG 1 ATOM 2710 C CD . GLN C 3 55 ? 27.930 -30.628 44.616 1.00 63.96 ? 55 GLN C CD 1 ATOM 2711 O OE1 . GLN C 3 55 ? 27.633 -30.174 43.506 1.00 66.08 ? 55 GLN C OE1 1 ATOM 2712 N NE2 . GLN C 3 55 ? 29.189 -30.672 45.061 1.00 62.88 ? 55 GLN C NE2 1 ATOM 2713 N N . THR C 3 56 ? 26.256 -34.127 44.206 1.00 65.17 ? 56 THR C N 1 ATOM 2714 C CA . THR C 3 56 ? 26.472 -35.518 44.615 1.00 66.83 ? 56 THR C CA 1 ATOM 2715 C C . THR C 3 56 ? 26.475 -35.620 46.140 1.00 64.96 ? 56 THR C C 1 ATOM 2716 O O . THR C 3 56 ? 27.201 -34.892 46.800 1.00 63.98 ? 56 THR C O 1 ATOM 2717 C CB . THR C 3 56 ? 27.805 -36.070 44.072 1.00 69.27 ? 56 THR C CB 1 ATOM 2718 O OG1 . THR C 3 56 ? 28.869 -35.182 44.432 1.00 71.31 ? 56 THR C OG1 1 ATOM 2719 C CG2 . THR C 3 56 ? 27.759 -36.217 42.547 1.00 69.84 ? 56 THR C CG2 1 ATOM 2720 N N . GLY C 3 57 ? 25.645 -36.512 46.682 1.00 66.11 ? 57 GLY C N 1 ATOM 2721 C CA . GLY C 3 57 ? 25.465 -36.663 48.132 1.00 65.42 ? 57 GLY C CA 1 ATOM 2722 C C . GLY C 3 57 ? 24.153 -36.108 48.665 1.00 63.75 ? 57 GLY C C 1 ATOM 2723 O O . GLY C 3 57 ? 23.621 -36.612 49.655 1.00 63.31 ? 57 GLY C O 1 ATOM 2724 N N . ILE C 3 58 ? 23.620 -35.084 48.005 1.00 62.70 ? 58 ILE C N 1 ATOM 2725 C CA . ILE C 3 58 ? 22.444 -34.373 48.500 1.00 62.11 ? 58 ILE C CA 1 ATOM 2726 C C . ILE C 3 58 ? 21.181 -35.227 48.303 1.00 61.81 ? 58 ILE C C 1 ATOM 2727 O O . ILE C 3 58 ? 21.022 -35.848 47.248 1.00 60.83 ? 58 ILE C O 1 ATOM 2728 C CB . ILE C 3 58 ? 22.285 -32.995 47.807 1.00 60.86 ? 58 ILE C CB 1 ATOM 2729 C CG1 . ILE C 3 58 ? 23.509 -32.099 48.079 1.00 59.97 ? 58 ILE C CG1 1 ATOM 2730 C CG2 . ILE C 3 58 ? 21.008 -32.278 48.247 1.00 61.22 ? 58 ILE C CG2 1 ATOM 2731 C CD1 . ILE C 3 58 ? 23.709 -31.657 49.518 1.00 58.57 ? 58 ILE C CD1 1 ATOM 2732 N N . PRO C 3 59 ? 20.288 -35.264 49.322 1.00 61.49 ? 59 PRO C N 1 ATOM 2733 C CA . PRO C 3 59 ? 18.998 -35.953 49.228 1.00 60.91 ? 59 PRO C CA 1 ATOM 2734 C C . PRO C 3 59 ? 18.180 -35.633 47.977 1.00 59.63 ? 59 PRO C C 1 ATOM 2735 O O . PRO C 3 59 ? 18.173 -34.493 47.508 1.00 62.53 ? 59 PRO C O 1 ATOM 2736 C CB . PRO C 3 59 ? 18.242 -35.441 50.456 1.00 60.84 ? 59 PRO C CB 1 ATOM 2737 C CG . PRO C 3 59 ? 19.296 -35.156 51.454 1.00 60.45 ? 59 PRO C CG 1 ATOM 2738 C CD . PRO C 3 59 ? 20.546 -34.805 50.703 1.00 60.68 ? 59 PRO C CD 1 ATOM 2739 N N . SER C 3 60 ? 17.469 -36.637 47.478 1.00 58.38 ? 60 SER C N 1 ATOM 2740 C CA . SER C 3 60 ? 16.588 -36.473 46.322 1.00 56.19 ? 60 SER C CA 1 ATOM 2741 C C . SER C 3 60 ? 15.350 -35.598 46.579 1.00 55.09 ? 60 SER C C 1 ATOM 2742 O O . SER C 3 60 ? 14.677 -35.211 45.627 1.00 54.98 ? 60 SER C O 1 ATOM 2743 C CB . SER C 3 60 ? 16.166 -37.846 45.793 1.00 54.52 ? 60 SER C CB 1 ATOM 2744 O OG . SER C 3 60 ? 17.299 -38.560 45.332 1.00 52.81 ? 60 SER C OG 1 ATOM 2745 N N . ARG C 3 61 ? 15.041 -35.296 47.844 1.00 56.20 ? 61 ARG C N 1 ATOM 2746 C CA . ARG C 3 61 ? 13.943 -34.364 48.176 1.00 57.79 ? 61 ARG C CA 1 ATOM 2747 C C . ARG C 3 61 ? 14.194 -32.916 47.738 1.00 57.25 ? 61 ARG C C 1 ATOM 2748 O O . ARG C 3 61 ? 13.240 -32.150 47.580 1.00 57.78 ? 61 ARG C O 1 ATOM 2749 C CB . ARG C 3 61 ? 13.590 -34.402 49.675 1.00 59.12 ? 61 ARG C CB 1 ATOM 2750 C CG . ARG C 3 61 ? 14.687 -33.960 50.644 1.00 59.51 ? 61 ARG C CG 1 ATOM 2751 C CD . ARG C 3 61 ? 14.161 -33.929 52.071 1.00 58.82 ? 61 ARG C CD 1 ATOM 2752 N NE . ARG C 3 61 ? 15.211 -33.704 53.068 1.00 58.15 ? 61 ARG C NE 1 ATOM 2753 C CZ . ARG C 3 61 ? 16.069 -34.627 53.510 1.00 58.28 ? 61 ARG C CZ 1 ATOM 2754 N NH1 . ARG C 3 61 ? 16.069 -35.868 53.031 1.00 59.38 ? 61 ARG C NH1 1 ATOM 2755 N NH2 . ARG C 3 61 ? 16.964 -34.295 54.433 1.00 58.69 ? 61 ARG C NH2 1 ATOM 2756 N N . PHE C 3 62 ? 15.462 -32.545 47.561 1.00 55.73 ? 62 PHE C N 1 ATOM 2757 C CA . PHE C 3 62 ? 15.819 -31.227 47.028 1.00 55.62 ? 62 PHE C CA 1 ATOM 2758 C C . PHE C 3 62 ? 15.771 -31.236 45.508 1.00 52.32 ? 62 PHE C C 1 ATOM 2759 O O . PHE C 3 62 ? 16.285 -32.158 44.881 1.00 55.19 ? 62 PHE C O 1 ATOM 2760 C CB . PHE C 3 62 ? 17.221 -30.816 47.485 1.00 56.85 ? 62 PHE C CB 1 ATOM 2761 C CG . PHE C 3 62 ? 17.338 -30.631 48.964 1.00 55.50 ? 62 PHE C CG 1 ATOM 2762 C CD1 . PHE C 3 62 ? 16.899 -29.458 49.558 1.00 55.36 ? 62 PHE C CD1 1 ATOM 2763 C CD2 . PHE C 3 62 ? 17.875 -31.634 49.765 1.00 55.42 ? 62 PHE C CD2 1 ATOM 2764 C CE1 . PHE C 3 62 ? 16.999 -29.283 50.928 1.00 56.99 ? 62 PHE C CE1 1 ATOM 2765 C CE2 . PHE C 3 62 ? 17.977 -31.468 51.135 1.00 55.34 ? 62 PHE C CE2 1 ATOM 2766 C CZ . PHE C 3 62 ? 17.539 -30.289 51.718 1.00 57.14 ? 62 PHE C CZ 1 ATOM 2767 N N . SER C 3 63 ? 15.159 -30.209 44.924 1.00 48.63 ? 63 SER C N 1 ATOM 2768 C CA . SER C 3 63 ? 15.130 -30.040 43.472 1.00 46.73 ? 63 SER C CA 1 ATOM 2769 C C . SER C 3 63 ? 15.054 -28.567 43.095 1.00 45.54 ? 63 SER C C 1 ATOM 2770 O O . SER C 3 63 ? 14.499 -27.752 43.830 1.00 44.50 ? 63 SER C O 1 ATOM 2771 C CB . SER C 3 63 ? 13.952 -30.793 42.856 1.00 45.89 ? 63 SER C CB 1 ATOM 2772 O OG . SER C 3 63 ? 12.725 -30.209 43.236 1.00 46.04 ? 63 SER C OG 1 ATOM 2773 N N . GLY C 3 64 ? 15.623 -28.244 41.940 1.00 44.49 ? 64 GLY C N 1 ATOM 2774 C CA . GLY C 3 64 ? 15.671 -26.883 41.443 1.00 44.82 ? 64 GLY C CA 1 ATOM 2775 C C . GLY C 3 64 ? 14.912 -26.733 40.145 1.00 45.85 ? 64 GLY C C 1 ATOM 2776 O O . GLY C 3 64 ? 14.628 -27.714 39.457 1.00 48.35 ? 64 GLY C O 1 ATOM 2777 N N . SER C 3 65 ? 14.581 -25.492 39.815 1.00 47.03 ? 65 SER C N 1 ATOM 2778 C CA . SER C 3 65 ? 13.855 -25.175 38.587 1.00 47.42 ? 65 SER C CA 1 ATOM 2779 C C . SER C 3 65 ? 13.874 -23.681 38.344 1.00 46.30 ? 65 SER C C 1 ATOM 2780 O O . SER C 3 65 ? 14.118 -22.899 39.262 1.00 45.55 ? 65 SER C O 1 ATOM 2781 C CB . SER C 3 65 ? 12.408 -25.671 38.665 1.00 49.49 ? 65 SER C CB 1 ATOM 2782 O OG . SER C 3 65 ? 11.860 -25.450 39.955 1.00 54.85 ? 65 SER C OG 1 ATOM 2783 N N . GLY C 3 66 ? 13.620 -23.303 37.098 1.00 46.64 ? 66 GLY C N 1 ATOM 2784 C CA . GLY C 3 66 ? 13.590 -21.908 36.695 1.00 48.31 ? 66 GLY C CA 1 ATOM 2785 C C . GLY C 3 66 ? 14.237 -21.651 35.352 1.00 51.13 ? 66 GLY C C 1 ATOM 2786 O O . GLY C 3 66 ? 14.876 -22.529 34.750 1.00 48.71 ? 66 GLY C O 1 ATOM 2787 N N . SER C 3 67 ? 14.045 -20.424 34.884 1.00 53.34 ? 67 SER C N 1 ATOM 2788 C CA . SER C 3 67 ? 14.726 -19.921 33.701 1.00 54.44 ? 67 SER C CA 1 ATOM 2789 C C . SER C 3 67 ? 14.663 -18.405 33.706 1.00 53.85 ? 67 SER C C 1 ATOM 2790 O O . SER C 3 67 ? 13.851 -17.807 34.416 1.00 52.77 ? 67 SER C O 1 ATOM 2791 C CB . SER C 3 67 ? 14.099 -20.481 32.415 1.00 56.04 ? 67 SER C CB 1 ATOM 2792 O OG . SER C 3 67 ? 12.823 -19.916 32.157 1.00 57.33 ? 67 SER C OG 1 ATOM 2793 N N . GLY C 3 68 ? 15.533 -17.795 32.910 1.00 56.08 ? 68 GLY C N 1 ATOM 2794 C CA . GLY C 3 68 ? 15.564 -16.347 32.755 1.00 56.78 ? 68 GLY C CA 1 ATOM 2795 C C . GLY C 3 68 ? 15.855 -15.644 34.063 1.00 57.57 ? 68 GLY C C 1 ATOM 2796 O O . GLY C 3 68 ? 17.005 -15.569 34.504 1.00 57.91 ? 68 GLY C O 1 ATOM 2797 N N . THR C 3 69 ? 14.791 -15.171 34.701 1.00 59.40 ? 69 THR C N 1 ATOM 2798 C CA . THR C 3 69 ? 14.899 -14.302 35.872 1.00 59.14 ? 69 THR C CA 1 ATOM 2799 C C . THR C 3 69 ? 14.403 -14.930 37.195 1.00 59.69 ? 69 THR C C 1 ATOM 2800 O O . THR C 3 69 ? 14.941 -14.607 38.261 1.00 58.51 ? 69 THR C O 1 ATOM 2801 C CB . THR C 3 69 ? 14.211 -12.950 35.571 1.00 59.31 ? 69 THR C CB 1 ATOM 2802 O OG1 . THR C 3 69 ? 14.699 -11.953 36.472 1.00 61.04 ? 69 THR C OG1 1 ATOM 2803 C CG2 . THR C 3 69 ? 12.682 -13.041 35.652 1.00 59.49 ? 69 THR C CG2 1 ATOM 2804 N N . ASP C 3 70 ? 13.424 -15.842 37.121 1.00 59.22 ? 70 ASP C N 1 ATOM 2805 C CA . ASP C 3 70 ? 12.808 -16.467 38.306 1.00 58.08 ? 70 ASP C CA 1 ATOM 2806 C C . ASP C 3 70 ? 13.231 -17.924 38.496 1.00 55.54 ? 70 ASP C C 1 ATOM 2807 O O . ASP C 3 70 ? 13.194 -18.722 37.556 1.00 55.58 ? 70 ASP C O 1 ATOM 2808 C CB . ASP C 3 70 ? 11.285 -16.426 38.188 1.00 59.76 ? 70 ASP C CB 1 ATOM 2809 C CG . ASP C 3 70 ? 10.742 -15.020 38.001 1.00 61.50 ? 70 ASP C CG 1 ATOM 2810 O OD1 . ASP C 3 70 ? 11.284 -14.063 38.596 1.00 63.76 ? 70 ASP C OD1 1 ATOM 2811 O OD2 . ASP C 3 70 ? 9.749 -14.878 37.259 1.00 64.54 ? 70 ASP C OD2 1 ATOM 2812 N N . TYR C 3 71 ? 13.611 -18.263 39.726 1.00 53.69 ? 71 TYR C N 1 ATOM 2813 C CA . TYR C 3 71 ? 14.144 -19.589 40.066 1.00 52.61 ? 71 TYR C CA 1 ATOM 2814 C C . TYR C 3 71 ? 13.516 -20.106 41.357 1.00 51.97 ? 71 TYR C C 1 ATOM 2815 O O . TYR C 3 71 ? 12.985 -19.324 42.144 1.00 52.48 ? 71 TYR C O 1 ATOM 2816 C CB . TYR C 3 71 ? 15.675 -19.526 40.170 1.00 50.74 ? 71 TYR C CB 1 ATOM 2817 C CG . TYR C 3 71 ? 16.288 -19.158 38.848 1.00 50.76 ? 71 TYR C CG 1 ATOM 2818 C CD1 . TYR C 3 71 ? 16.443 -17.824 38.475 1.00 50.03 ? 71 TYR C CD1 1 ATOM 2819 C CD2 . TYR C 3 71 ? 16.649 -20.145 37.929 1.00 51.76 ? 71 TYR C CD2 1 ATOM 2820 C CE1 . TYR C 3 71 ? 16.967 -17.484 37.237 1.00 50.18 ? 71 TYR C CE1 1 ATOM 2821 C CE2 . TYR C 3 71 ? 17.186 -19.815 36.693 1.00 49.76 ? 71 TYR C CE2 1 ATOM 2822 C CZ . TYR C 3 71 ? 17.338 -18.486 36.351 1.00 49.39 ? 71 TYR C CZ 1 ATOM 2823 O OH . TYR C 3 71 ? 17.864 -18.160 35.130 1.00 47.65 ? 71 TYR C OH 1 ATOM 2824 N N . THR C 3 72 ? 13.564 -21.422 41.557 1.00 50.98 ? 72 THR C N 1 ATOM 2825 C CA . THR C 3 72 ? 12.930 -22.051 42.719 1.00 51.22 ? 72 THR C CA 1 ATOM 2826 C C . THR C 3 72 ? 13.676 -23.283 43.200 1.00 50.64 ? 72 THR C C 1 ATOM 2827 O O . THR C 3 72 ? 14.160 -24.074 42.394 1.00 51.01 ? 72 THR C O 1 ATOM 2828 C CB . THR C 3 72 ? 11.477 -22.486 42.422 1.00 51.02 ? 72 THR C CB 1 ATOM 2829 O OG1 . THR C 3 72 ? 11.403 -23.026 41.099 1.00 53.74 ? 72 THR C OG1 1 ATOM 2830 C CG2 . THR C 3 72 ? 10.516 -21.321 42.536 1.00 50.54 ? 72 THR C CG2 1 ATOM 2831 N N . LEU C 3 73 ? 13.759 -23.411 44.523 1.00 50.28 ? 73 LEU C N 1 ATOM 2832 C CA . LEU C 3 73 ? 14.205 -24.618 45.203 1.00 51.63 ? 73 LEU C CA 1 ATOM 2833 C C . LEU C 3 73 ? 12.973 -25.219 45.870 1.00 53.99 ? 73 LEU C C 1 ATOM 2834 O O . LEU C 3 73 ? 12.175 -24.496 46.473 1.00 52.71 ? 73 LEU C O 1 ATOM 2835 C CB . LEU C 3 73 ? 15.265 -24.282 46.259 1.00 51.87 ? 73 LEU C CB 1 ATOM 2836 C CG . LEU C 3 73 ? 15.745 -25.371 47.236 1.00 51.13 ? 73 LEU C CG 1 ATOM 2837 C CD1 . LEU C 3 73 ? 16.595 -26.401 46.515 1.00 50.92 ? 73 LEU C CD1 1 ATOM 2838 C CD2 . LEU C 3 73 ? 16.524 -24.752 48.390 1.00 50.85 ? 73 LEU C CD2 1 ATOM 2839 N N . THR C 3 74 ? 12.824 -26.537 45.759 1.00 55.44 ? 74 THR C N 1 ATOM 2840 C CA . THR C 3 74 ? 11.711 -27.252 46.367 1.00 54.35 ? 74 THR C CA 1 ATOM 2841 C C . THR C 3 74 ? 12.261 -28.331 47.273 1.00 53.66 ? 74 THR C C 1 ATOM 2842 O O . THR C 3 74 ? 13.218 -29.014 46.920 1.00 53.61 ? 74 THR C O 1 ATOM 2843 C CB . THR C 3 74 ? 10.790 -27.885 45.304 1.00 54.99 ? 74 THR C CB 1 ATOM 2844 O OG1 . THR C 3 74 ? 10.203 -26.852 44.501 1.00 54.29 ? 74 THR C OG1 1 ATOM 2845 C CG2 . THR C 3 74 ? 9.664 -28.710 45.955 1.00 55.16 ? 74 THR C CG2 1 ATOM 2846 N N . ILE C 3 75 ? 11.660 -28.448 48.453 1.00 54.88 ? 75 ILE C N 1 ATOM 2847 C CA . ILE C 3 75 ? 11.883 -29.564 49.357 1.00 56.47 ? 75 ILE C CA 1 ATOM 2848 C C . ILE C 3 75 ? 10.532 -30.258 49.416 1.00 55.93 ? 75 ILE C C 1 ATOM 2849 O O . ILE C 3 75 ? 9.575 -29.695 49.951 1.00 55.27 ? 75 ILE C O 1 ATOM 2850 C CB . ILE C 3 75 ? 12.331 -29.100 50.763 1.00 58.59 ? 75 ILE C CB 1 ATOM 2851 C CG1 . ILE C 3 75 ? 13.449 -28.051 50.658 1.00 58.43 ? 75 ILE C CG1 1 ATOM 2852 C CG2 . ILE C 3 75 ? 12.786 -30.296 51.602 1.00 58.80 ? 75 ILE C CG2 1 ATOM 2853 C CD1 . ILE C 3 75 ? 13.978 -27.572 51.993 1.00 59.32 ? 75 ILE C CD1 1 ATOM 2854 N N . SER C 3 76 ? 10.455 -31.461 48.849 1.00 56.66 ? 76 SER C N 1 ATOM 2855 C CA . SER C 3 76 ? 9.163 -32.119 48.591 1.00 58.67 ? 76 SER C CA 1 ATOM 2856 C C . SER C 3 76 ? 8.497 -32.640 49.870 1.00 59.30 ? 76 SER C C 1 ATOM 2857 O O . SER C 3 76 ? 7.293 -32.464 50.072 1.00 57.17 ? 76 SER C O 1 ATOM 2858 C CB . SER C 3 76 ? 9.323 -33.249 47.562 1.00 58.05 ? 76 SER C CB 1 ATOM 2859 O OG . SER C 3 76 ? 10.395 -34.112 47.908 1.00 60.38 ? 76 SER C OG 1 ATOM 2860 N N . SER C 3 77 ? 9.286 -33.286 50.721 1.00 61.49 ? 77 SER C N 1 ATOM 2861 C CA . SER C 3 77 ? 8.821 -33.750 52.023 1.00 62.70 ? 77 SER C CA 1 ATOM 2862 C C . SER C 3 77 ? 9.827 -33.269 53.064 1.00 62.08 ? 77 SER C C 1 ATOM 2863 O O . SER C 3 77 ? 10.947 -33.781 53.140 1.00 59.67 ? 77 SER C O 1 ATOM 2864 C CB . SER C 3 77 ? 8.699 -35.274 52.024 1.00 64.56 ? 77 SER C CB 1 ATOM 2865 O OG . SER C 3 77 ? 8.029 -35.737 53.182 1.00 67.41 ? 77 SER C OG 1 ATOM 2866 N N . LEU C 3 78 ? 9.425 -32.271 53.846 1.00 60.85 ? 78 LEU C N 1 ATOM 2867 C CA . LEU C 3 78 ? 10.332 -31.604 54.780 1.00 61.58 ? 78 LEU C CA 1 ATOM 2868 C C . LEU C 3 78 ? 10.745 -32.485 55.964 1.00 61.80 ? 78 LEU C C 1 ATOM 2869 O O . LEU C 3 78 ? 9.897 -32.927 56.732 1.00 60.89 ? 78 LEU C O 1 ATOM 2870 C CB . LEU C 3 78 ? 9.676 -30.322 55.301 1.00 62.15 ? 78 LEU C CB 1 ATOM 2871 C CG . LEU C 3 78 ? 10.445 -29.460 56.302 1.00 61.87 ? 78 LEU C CG 1 ATOM 2872 C CD1 . LEU C 3 78 ? 11.835 -29.125 55.783 1.00 62.46 ? 78 LEU C CD1 1 ATOM 2873 C CD2 . LEU C 3 78 ? 9.661 -28.192 56.603 1.00 62.34 ? 78 LEU C CD2 1 ATOM 2874 N N . HIS C 3 79 ? 12.044 -32.738 56.097 1.00 63.85 ? 79 HIS C N 1 ATOM 2875 C CA . HIS C 3 79 ? 12.595 -33.390 57.287 1.00 66.09 ? 79 HIS C CA 1 ATOM 2876 C C . HIS C 3 79 ? 12.935 -32.332 58.339 1.00 70.00 ? 79 HIS C C 1 ATOM 2877 O O . HIS C 3 79 ? 12.973 -31.134 58.042 1.00 68.18 ? 79 HIS C O 1 ATOM 2878 C CB . HIS C 3 79 ? 13.837 -34.219 56.934 1.00 67.54 ? 79 HIS C CB 1 ATOM 2879 C CG . HIS C 3 79 ? 13.526 -35.489 56.205 1.00 70.42 ? 79 HIS C CG 1 ATOM 2880 N ND1 . HIS C 3 79 ? 13.792 -36.734 56.732 1.00 74.40 ? 79 HIS C ND1 1 ATOM 2881 C CD2 . HIS C 3 79 ? 12.953 -35.708 54.998 1.00 73.04 ? 79 HIS C CD2 1 ATOM 2882 C CE1 . HIS C 3 79 ? 13.402 -37.665 55.878 1.00 74.63 ? 79 HIS C CE1 1 ATOM 2883 N NE2 . HIS C 3 79 ? 12.890 -37.069 54.818 1.00 72.93 ? 79 HIS C NE2 1 ATOM 2884 N N . SER C 3 80 ? 13.169 -32.785 59.570 1.00 76.69 ? 80 SER C N 1 ATOM 2885 C CA . SER C 3 80 ? 13.555 -31.903 60.684 1.00 78.27 ? 80 SER C CA 1 ATOM 2886 C C . SER C 3 80 ? 14.987 -31.362 60.533 1.00 80.02 ? 80 SER C C 1 ATOM 2887 O O . SER C 3 80 ? 15.257 -30.208 60.886 1.00 78.36 ? 80 SER C O 1 ATOM 2888 C CB . SER C 3 80 ? 13.417 -32.636 62.023 1.00 78.06 ? 80 SER C CB 1 ATOM 2889 O OG . SER C 3 80 ? 14.406 -33.646 62.160 1.00 78.72 ? 80 SER C OG 1 ATOM 2890 N N . GLU C 3 81 ? 15.890 -32.190 59.997 1.00 80.15 ? 81 GLU C N 1 ATOM 2891 C CA . GLU C 3 81 ? 17.286 -31.784 59.758 1.00 80.90 ? 81 GLU C CA 1 ATOM 2892 C C . GLU C 3 81 ? 17.503 -30.883 58.529 1.00 75.17 ? 81 GLU C C 1 ATOM 2893 O O . GLU C 3 81 ? 18.643 -30.632 58.142 1.00 70.46 ? 81 GLU C O 1 ATOM 2894 C CB . GLU C 3 81 ? 18.194 -33.023 59.681 1.00 86.92 ? 81 GLU C CB 1 ATOM 2895 C CG . GLU C 3 81 ? 18.297 -33.802 60.992 1.00 93.71 ? 81 GLU C CG 1 ATOM 2896 C CD . GLU C 3 81 ? 18.894 -33.003 62.154 1.00 98.18 ? 81 GLU C CD 1 ATOM 2897 O OE1 . GLU C 3 81 ? 19.607 -31.996 61.926 1.00 98.19 ? 81 GLU C OE1 1 ATOM 2898 O OE2 . GLU C 3 81 ? 18.651 -33.393 63.316 1.00 102.08 ? 81 GLU C OE2 1 ATOM 2899 N N . ASP C 3 82 ? 16.415 -30.403 57.926 1.00 72.51 ? 82 ASP C N 1 ATOM 2900 C CA . ASP C 3 82 ? 16.459 -29.356 56.905 1.00 71.95 ? 82 ASP C CA 1 ATOM 2901 C C . ASP C 3 82 ? 16.179 -27.962 57.489 1.00 72.73 ? 82 ASP C C 1 ATOM 2902 O O . ASP C 3 82 ? 15.964 -27.004 56.743 1.00 73.35 ? 82 ASP C O 1 ATOM 2903 C CB . ASP C 3 82 ? 15.435 -29.671 55.802 1.00 69.12 ? 82 ASP C CB 1 ATOM 2904 C CG . ASP C 3 82 ? 15.705 -30.993 55.101 1.00 65.13 ? 82 ASP C CG 1 ATOM 2905 O OD1 . ASP C 3 82 ? 16.889 -31.362 54.927 1.00 61.33 ? 82 ASP C OD1 1 ATOM 2906 O OD2 . ASP C 3 82 ? 14.724 -31.663 54.709 1.00 60.41 ? 82 ASP C OD2 1 ATOM 2907 N N . LEU C 3 83 ? 16.173 -27.844 58.815 1.00 74.09 ? 83 LEU C N 1 ATOM 2908 C CA . LEU C 3 83 ? 15.986 -26.552 59.464 1.00 75.19 ? 83 LEU C CA 1 ATOM 2909 C C . LEU C 3 83 ? 17.299 -25.777 59.358 1.00 72.63 ? 83 LEU C C 1 ATOM 2910 O O . LEU C 3 83 ? 18.284 -26.106 60.027 1.00 74.49 ? 83 LEU C O 1 ATOM 2911 C CB . LEU C 3 83 ? 15.540 -26.734 60.922 1.00 77.64 ? 83 LEU C CB 1 ATOM 2912 C CG . LEU C 3 83 ? 15.386 -25.462 61.769 1.00 78.49 ? 83 LEU C CG 1 ATOM 2913 C CD1 . LEU C 3 83 ? 13.986 -25.333 62.353 1.00 79.90 ? 83 LEU C CD1 1 ATOM 2914 C CD2 . LEU C 3 83 ? 16.448 -25.402 62.865 1.00 77.56 ? 83 LEU C CD2 1 ATOM 2915 N N . ALA C 3 84 ? 17.303 -24.770 58.488 1.00 66.37 ? 84 ALA C N 1 ATOM 2916 C CA . ALA C 3 84 ? 18.490 -23.970 58.209 1.00 64.69 ? 84 ALA C CA 1 ATOM 2917 C C . ALA C 3 84 ? 18.097 -22.697 57.459 1.00 66.79 ? 84 ALA C C 1 ATOM 2918 O O . ALA C 3 84 ? 16.907 -22.442 57.228 1.00 67.88 ? 84 ALA C O 1 ATOM 2919 C CB . ALA C 3 84 ? 19.482 -24.786 57.385 1.00 63.74 ? 84 ALA C CB 1 ATOM 2920 N N . THR C 3 85 ? 19.099 -21.894 57.104 1.00 67.88 ? 85 THR C N 1 ATOM 2921 C CA . THR C 3 85 ? 18.932 -20.789 56.161 1.00 67.21 ? 85 THR C CA 1 ATOM 2922 C C . THR C 3 85 ? 19.374 -21.267 54.770 1.00 65.43 ? 85 THR C C 1 ATOM 2923 O O . THR C 3 85 ? 20.402 -21.949 54.634 1.00 61.72 ? 85 THR C O 1 ATOM 2924 C CB . THR C 3 85 ? 19.757 -19.556 56.584 1.00 69.68 ? 85 THR C CB 1 ATOM 2925 O OG1 . THR C 3 85 ? 19.631 -19.354 57.997 1.00 72.46 ? 85 THR C OG1 1 ATOM 2926 C CG2 . THR C 3 85 ? 19.280 -18.304 55.852 1.00 70.31 ? 85 THR C CG2 1 ATOM 2927 N N . TYR C 3 86 ? 18.587 -20.912 53.753 1.00 62.95 ? 86 TYR C N 1 ATOM 2928 C CA . TYR C 3 86 ? 18.819 -21.339 52.374 1.00 61.28 ? 86 TYR C CA 1 ATOM 2929 C C . TYR C 3 86 ? 19.123 -20.143 51.480 1.00 62.92 ? 86 TYR C C 1 ATOM 2930 O O . TYR C 3 86 ? 18.261 -19.288 51.262 1.00 62.57 ? 86 TYR C O 1 ATOM 2931 C CB . TYR C 3 86 ? 17.597 -22.093 51.851 1.00 59.53 ? 86 TYR C CB 1 ATOM 2932 C CG . TYR C 3 86 ? 17.450 -23.453 52.477 1.00 58.24 ? 86 TYR C CG 1 ATOM 2933 C CD1 . TYR C 3 86 ? 18.226 -24.523 52.040 1.00 57.54 ? 86 TYR C CD1 1 ATOM 2934 C CD2 . TYR C 3 86 ? 16.558 -23.669 53.527 1.00 57.39 ? 86 TYR C CD2 1 ATOM 2935 C CE1 . TYR C 3 86 ? 18.110 -25.775 52.621 1.00 57.94 ? 86 TYR C CE1 1 ATOM 2936 C CE2 . TYR C 3 86 ? 16.434 -24.918 54.113 1.00 57.46 ? 86 TYR C CE2 1 ATOM 2937 C CZ . TYR C 3 86 ? 17.213 -25.967 53.655 1.00 57.30 ? 86 TYR C CZ 1 ATOM 2938 O OH . TYR C 3 86 ? 17.101 -27.206 54.222 1.00 55.25 ? 86 TYR C OH 1 ATOM 2939 N N . TYR C 3 87 ? 20.348 -20.100 50.956 1.00 63.75 ? 87 TYR C N 1 ATOM 2940 C CA . TYR C 3 87 ? 20.818 -18.990 50.131 1.00 64.04 ? 87 TYR C CA 1 ATOM 2941 C C . TYR C 3 87 ? 20.936 -19.413 48.665 1.00 61.67 ? 87 TYR C C 1 ATOM 2942 O O . TYR C 3 87 ? 21.570 -20.432 48.372 1.00 60.66 ? 87 TYR C O 1 ATOM 2943 C CB . TYR C 3 87 ? 22.185 -18.527 50.629 1.00 67.21 ? 87 TYR C CB 1 ATOM 2944 C CG . TYR C 3 87 ? 22.196 -17.933 52.025 1.00 72.13 ? 87 TYR C CG 1 ATOM 2945 C CD1 . TYR C 3 87 ? 22.044 -16.558 52.219 1.00 75.98 ? 87 TYR C CD1 1 ATOM 2946 C CD2 . TYR C 3 87 ? 22.383 -18.738 53.152 1.00 74.73 ? 87 TYR C CD2 1 ATOM 2947 C CE1 . TYR C 3 87 ? 22.063 -16.003 53.492 1.00 77.15 ? 87 TYR C CE1 1 ATOM 2948 C CE2 . TYR C 3 87 ? 22.403 -18.193 54.429 1.00 75.73 ? 87 TYR C CE2 1 ATOM 2949 C CZ . TYR C 3 87 ? 22.245 -16.826 54.591 1.00 79.04 ? 87 TYR C CZ 1 ATOM 2950 O OH . TYR C 3 87 ? 22.264 -16.276 55.848 1.00 84.80 ? 87 TYR C OH 1 ATOM 2951 N N . CYS C 3 88 ? 20.331 -18.641 47.756 1.00 56.92 ? 88 CYS C N 1 ATOM 2952 C CA . CYS C 3 88 ? 20.593 -18.781 46.323 1.00 54.83 ? 88 CYS C CA 1 ATOM 2953 C C . CYS C 3 88 ? 21.752 -17.862 45.923 1.00 54.01 ? 88 CYS C C 1 ATOM 2954 O O . CYS C 3 88 ? 22.034 -16.877 46.606 1.00 53.19 ? 88 CYS C O 1 ATOM 2955 C CB . CYS C 3 88 ? 19.347 -18.483 45.480 1.00 55.09 ? 88 CYS C CB 1 ATOM 2956 S SG . CYS C 3 88 ? 18.598 -16.859 45.715 1.00 57.00 ? 88 CYS C SG 1 ATOM 2957 N N . TYR C 3 89 ? 22.447 -18.208 44.839 1.00 52.13 ? 89 TYR C N 1 ATOM 2958 C CA . TYR C 3 89 ? 23.505 -17.345 44.296 1.00 49.43 ? 89 TYR C CA 1 ATOM 2959 C C . TYR C 3 89 ? 23.748 -17.545 42.797 1.00 48.19 ? 89 TYR C C 1 ATOM 2960 O O . TYR C 3 89 ? 23.503 -18.619 42.245 1.00 46.65 ? 89 TYR C O 1 ATOM 2961 C CB . TYR C 3 89 ? 24.812 -17.459 45.108 1.00 47.75 ? 89 TYR C CB 1 ATOM 2962 C CG . TYR C 3 89 ? 25.745 -18.616 44.792 1.00 45.63 ? 89 TYR C CG 1 ATOM 2963 C CD1 . TYR C 3 89 ? 26.729 -18.496 43.819 1.00 45.19 ? 89 TYR C CD1 1 ATOM 2964 C CD2 . TYR C 3 89 ? 25.692 -19.801 45.519 1.00 45.80 ? 89 TYR C CD2 1 ATOM 2965 C CE1 . TYR C 3 89 ? 27.606 -19.536 43.547 1.00 44.81 ? 89 TYR C CE1 1 ATOM 2966 C CE2 . TYR C 3 89 ? 26.570 -20.850 45.260 1.00 44.64 ? 89 TYR C CE2 1 ATOM 2967 C CZ . TYR C 3 89 ? 27.524 -20.713 44.268 1.00 44.51 ? 89 TYR C CZ 1 ATOM 2968 O OH . TYR C 3 89 ? 28.396 -21.745 43.988 1.00 42.94 ? 89 TYR C OH 1 ATOM 2969 N N . GLN C 3 90 ? 24.260 -16.482 42.184 1.00 46.69 ? 90 GLN C N 1 ATOM 2970 C CA . GLN C 3 90 ? 24.381 -16.319 40.738 1.00 46.23 ? 90 GLN C CA 1 ATOM 2971 C C . GLN C 3 90 ? 25.860 -16.182 40.402 1.00 46.16 ? 90 GLN C C 1 ATOM 2972 O O . GLN C 3 90 ? 26.605 -15.577 41.167 1.00 50.36 ? 90 GLN C O 1 ATOM 2973 C CB . GLN C 3 90 ? 23.595 -15.066 40.330 1.00 45.19 ? 90 GLN C CB 1 ATOM 2974 C CG . GLN C 3 90 ? 23.971 -14.410 39.008 1.00 46.83 ? 90 GLN C CG 1 ATOM 2975 C CD . GLN C 3 90 ? 25.236 -13.565 39.065 1.00 45.99 ? 90 GLN C CD 1 ATOM 2976 O OE1 . GLN C 3 90 ? 26.112 -13.726 38.225 1.00 48.22 ? 90 GLN C OE1 1 ATOM 2977 N NE2 . GLN C 3 90 ? 25.341 -12.677 40.049 1.00 42.93 ? 90 GLN C NE2 1 ATOM 2978 N N . TYR C 3 91 ? 26.283 -16.722 39.259 1.00 45.56 ? 91 TYR C N 1 ATOM 2979 C CA . TYR C 3 91 ? 27.717 -16.787 38.927 1.00 45.23 ? 91 TYR C CA 1 ATOM 2980 C C . TYR C 3 91 ? 28.087 -16.626 37.435 1.00 44.54 ? 91 TYR C C 1 ATOM 2981 O O . TYR C 3 91 ? 29.101 -17.174 37.001 1.00 44.46 ? 91 TYR C O 1 ATOM 2982 C CB . TYR C 3 91 ? 28.322 -18.077 39.527 1.00 45.84 ? 91 TYR C CB 1 ATOM 2983 C CG . TYR C 3 91 ? 27.610 -19.364 39.142 1.00 47.00 ? 91 TYR C CG 1 ATOM 2984 C CD1 . TYR C 3 91 ? 26.492 -19.809 39.856 1.00 46.83 ? 91 TYR C CD1 1 ATOM 2985 C CD2 . TYR C 3 91 ? 28.062 -20.146 38.075 1.00 47.06 ? 91 TYR C CD2 1 ATOM 2986 C CE1 . TYR C 3 91 ? 25.845 -20.986 39.513 1.00 46.16 ? 91 TYR C CE1 1 ATOM 2987 C CE2 . TYR C 3 91 ? 27.420 -21.328 37.728 1.00 46.70 ? 91 TYR C CE2 1 ATOM 2988 C CZ . TYR C 3 91 ? 26.313 -21.740 38.448 1.00 46.86 ? 91 TYR C CZ 1 ATOM 2989 O OH . TYR C 3 91 ? 25.675 -22.902 38.104 1.00 46.95 ? 91 TYR C OH 1 ATOM 2990 N N . ILE C 3 92 ? 27.301 -15.853 36.673 1.00 44.09 ? 92 ILE C N 1 ATOM 2991 C CA . ILE C 3 92 ? 27.703 -15.432 35.308 1.00 46.48 ? 92 ILE C CA 1 ATOM 2992 C C . ILE C 3 92 ? 28.135 -13.978 35.247 1.00 48.31 ? 92 ILE C C 1 ATOM 2993 O O . ILE C 3 92 ? 29.028 -13.650 34.470 1.00 50.04 ? 92 ILE C O 1 ATOM 2994 C CB . ILE C 3 92 ? 26.659 -15.639 34.163 1.00 47.95 ? 92 ILE C CB 1 ATOM 2995 C CG1 . ILE C 3 92 ? 25.240 -15.890 34.674 1.00 49.70 ? 92 ILE C CG1 1 ATOM 2996 C CG2 . ILE C 3 92 ? 27.118 -16.738 33.211 1.00 48.84 ? 92 ILE C CG2 1 ATOM 2997 C CD1 . ILE C 3 92 ? 24.465 -14.630 34.975 1.00 51.60 ? 92 ILE C CD1 1 ATOM 2998 N N . ASN C 3 93 ? 27.487 -13.110 36.022 1.00 49.77 ? 93 ASN C N 1 ATOM 2999 C CA . ASN C 3 93 ? 27.805 -11.685 36.044 1.00 51.16 ? 93 ASN C CA 1 ATOM 3000 C C . ASN C 3 93 ? 28.149 -11.275 37.477 1.00 50.59 ? 93 ASN C C 1 ATOM 3001 O O . ASN C 3 93 ? 27.275 -10.918 38.270 1.00 54.54 ? 93 ASN C O 1 ATOM 3002 C CB . ASN C 3 93 ? 26.645 -10.869 35.465 1.00 52.46 ? 93 ASN C CB 1 ATOM 3003 C CG . ASN C 3 93 ? 27.116 -9.592 34.801 1.00 54.96 ? 93 ASN C CG 1 ATOM 3004 O OD1 . ASN C 3 93 ? 27.824 -8.790 35.415 1.00 56.58 ? 93 ASN C OD1 1 ATOM 3005 N ND2 . ASN C 3 93 ? 26.745 -9.406 33.531 1.00 54.49 ? 93 ASN C ND2 1 ATOM 3006 N N . GLY C 3 94 ? 29.439 -11.345 37.798 1.00 48.87 ? 94 GLY C N 1 ATOM 3007 C CA . GLY C 3 94 ? 29.913 -11.194 39.161 1.00 47.71 ? 94 GLY C CA 1 ATOM 3008 C C . GLY C 3 94 ? 29.493 -12.378 40.006 1.00 49.83 ? 94 GLY C C 1 ATOM 3009 O O . GLY C 3 94 ? 29.180 -13.458 39.480 1.00 51.14 ? 94 GLY C O 1 ATOM 3010 N N . TYR C 3 95 ? 29.507 -12.172 41.319 1.00 49.08 ? 95 TYR C N 1 ATOM 3011 C CA . TYR C 3 95 ? 29.067 -13.168 42.285 1.00 46.80 ? 95 TYR C CA 1 ATOM 3012 C C . TYR C 3 95 ? 28.191 -12.477 43.304 1.00 47.02 ? 95 TYR C C 1 ATOM 3013 O O . TYR C 3 95 ? 28.706 -11.844 44.226 1.00 50.91 ? 95 TYR C O 1 ATOM 3014 C CB . TYR C 3 95 ? 30.267 -13.785 42.985 1.00 45.51 ? 95 TYR C CB 1 ATOM 3015 C CG . TYR C 3 95 ? 31.155 -14.609 42.093 1.00 45.13 ? 95 TYR C CG 1 ATOM 3016 C CD1 . TYR C 3 95 ? 30.831 -15.925 41.789 1.00 44.76 ? 95 TYR C CD1 1 ATOM 3017 C CD2 . TYR C 3 95 ? 32.337 -14.081 41.567 1.00 44.38 ? 95 TYR C CD2 1 ATOM 3018 C CE1 . TYR C 3 95 ? 31.655 -16.697 40.985 1.00 44.82 ? 95 TYR C CE1 1 ATOM 3019 C CE2 . TYR C 3 95 ? 33.168 -14.844 40.760 1.00 43.60 ? 95 TYR C CE2 1 ATOM 3020 C CZ . TYR C 3 95 ? 32.822 -16.152 40.470 1.00 44.08 ? 95 TYR C CZ 1 ATOM 3021 O OH . TYR C 3 95 ? 33.627 -16.933 39.671 1.00 43.58 ? 95 TYR C OH 1 ATOM 3022 N N . THR C 3 96 ? 26.876 -12.578 43.129 1.00 47.26 ? 96 THR C N 1 ATOM 3023 C CA . THR C 3 96 ? 25.926 -12.020 44.093 1.00 49.45 ? 96 THR C CA 1 ATOM 3024 C C . THR C 3 96 ? 25.110 -13.120 44.746 1.00 51.84 ? 96 THR C C 1 ATOM 3025 O O . THR C 3 96 ? 24.838 -14.155 44.133 1.00 51.15 ? 96 THR C O 1 ATOM 3026 C CB . THR C 3 96 ? 24.956 -11.017 43.460 1.00 47.89 ? 96 THR C CB 1 ATOM 3027 O OG1 . THR C 3 96 ? 24.040 -11.708 42.601 1.00 46.65 ? 96 THR C OG1 1 ATOM 3028 C CG2 . THR C 3 96 ? 25.723 -9.961 42.692 1.00 47.90 ? 96 THR C CG2 1 ATOM 3029 N N . PHE C 3 97 ? 24.708 -12.853 45.987 1.00 53.51 ? 97 PHE C N 1 ATOM 3030 C CA . PHE C 3 97 ? 24.018 -13.810 46.833 1.00 53.05 ? 97 PHE C CA 1 ATOM 3031 C C . PHE C 3 97 ? 22.626 -13.305 47.201 1.00 55.61 ? 97 PHE C C 1 ATOM 3032 O O . PHE C 3 97 ? 22.352 -12.102 47.173 1.00 56.02 ? 97 PHE C O 1 ATOM 3033 C CB . PHE C 3 97 ? 24.834 -14.036 48.094 1.00 52.68 ? 97 PHE C CB 1 ATOM 3034 C CG . PHE C 3 97 ? 26.139 -14.747 47.857 1.00 52.83 ? 97 PHE C CG 1 ATOM 3035 C CD1 . PHE C 3 97 ? 27.219 -14.080 47.287 1.00 52.73 ? 97 PHE C CD1 1 ATOM 3036 C CD2 . PHE C 3 97 ? 26.296 -16.084 48.221 1.00 52.19 ? 97 PHE C CD2 1 ATOM 3037 C CE1 . PHE C 3 97 ? 28.425 -14.734 47.080 1.00 53.07 ? 97 PHE C CE1 1 ATOM 3038 C CE2 . PHE C 3 97 ? 27.497 -16.742 48.014 1.00 51.78 ? 97 PHE C CE2 1 ATOM 3039 C CZ . PHE C 3 97 ? 28.566 -16.066 47.444 1.00 52.97 ? 97 PHE C CZ 1 ATOM 3040 N N . GLY C 3 98 ? 21.750 -14.244 47.539 1.00 60.71 ? 98 GLY C N 1 ATOM 3041 C CA . GLY C 3 98 ? 20.394 -13.932 47.970 1.00 62.63 ? 98 GLY C CA 1 ATOM 3042 C C . GLY C 3 98 ? 20.354 -13.519 49.422 1.00 64.76 ? 98 GLY C C 1 ATOM 3043 O O . GLY C 3 98 ? 21.254 -13.855 50.202 1.00 58.27 ? 98 GLY C O 1 ATOM 3044 N N . THR C 3 99 ? 19.296 -12.791 49.774 1.00 71.25 ? 99 THR C N 1 ATOM 3045 C CA . THR C 3 99 ? 19.145 -12.219 51.115 1.00 78.09 ? 99 THR C CA 1 ATOM 3046 C C . THR C 3 99 ? 19.063 -13.299 52.199 1.00 80.89 ? 99 THR C C 1 ATOM 3047 O O . THR C 3 99 ? 19.702 -13.177 53.250 1.00 81.38 ? 99 THR C O 1 ATOM 3048 C CB . THR C 3 99 ? 17.924 -11.271 51.186 1.00 79.00 ? 99 THR C CB 1 ATOM 3049 O OG1 . THR C 3 99 ? 16.880 -11.746 50.323 1.00 77.86 ? 99 THR C OG1 1 ATOM 3050 C CG2 . THR C 3 99 ? 18.315 -9.857 50.754 1.00 78.86 ? 99 THR C CG2 1 ATOM 3051 N N . GLY C 3 100 ? 18.295 -14.353 51.916 1.00 85.35 ? 100 GLY C N 1 ATOM 3052 C CA . GLY C 3 100 ? 18.191 -15.536 52.781 1.00 88.36 ? 100 GLY C CA 1 ATOM 3053 C C . GLY C 3 100 ? 16.748 -15.845 53.151 1.00 89.43 ? 100 GLY C C 1 ATOM 3054 O O . GLY C 3 100 ? 16.000 -14.944 53.541 1.00 92.61 ? 100 GLY C O 1 ATOM 3055 N N . THR C 3 101 ? 16.358 -17.114 53.006 1.00 89.18 ? 101 THR C N 1 ATOM 3056 C CA . THR C 3 101 ? 15.070 -17.627 53.484 1.00 85.98 ? 101 THR C CA 1 ATOM 3057 C C . THR C 3 101 ? 15.365 -18.523 54.681 1.00 83.59 ? 101 THR C C 1 ATOM 3058 O O . THR C 3 101 ? 16.042 -19.544 54.528 1.00 79.24 ? 101 THR C O 1 ATOM 3059 C CB . THR C 3 101 ? 14.327 -18.441 52.396 1.00 84.98 ? 101 THR C CB 1 ATOM 3060 O OG1 . THR C 3 101 ? 13.880 -17.567 51.348 1.00 83.28 ? 101 THR C OG1 1 ATOM 3061 C CG2 . THR C 3 101 ? 13.116 -19.183 52.980 1.00 85.36 ? 101 THR C CG2 1 ATOM 3062 N N . LYS C 3 102 ? 14.871 -18.138 55.860 1.00 83.87 ? 102 LYS C N 1 ATOM 3063 C CA . LYS C 3 102 ? 15.056 -18.936 57.077 1.00 85.74 ? 102 LYS C CA 1 ATOM 3064 C C . LYS C 3 102 ? 13.889 -19.905 57.245 1.00 86.66 ? 102 LYS C C 1 ATOM 3065 O O . LYS C 3 102 ? 12.723 -19.506 57.133 1.00 83.28 ? 102 LYS C O 1 ATOM 3066 C CB . LYS C 3 102 ? 15.186 -18.045 58.311 1.00 84.90 ? 102 LYS C CB 1 ATOM 3067 C CG . LYS C 3 102 ? 15.639 -18.790 59.563 1.00 85.69 ? 102 LYS C CG 1 ATOM 3068 C CD . LYS C 3 102 ? 16.417 -17.892 60.516 1.00 87.21 ? 102 LYS C CD 1 ATOM 3069 C CE . LYS C 3 102 ? 17.867 -17.731 60.075 1.00 88.07 ? 102 LYS C CE 1 ATOM 3070 N NZ . LYS C 3 102 ? 18.589 -16.667 60.825 1.00 86.49 ? 102 LYS C NZ 1 ATOM 3071 N N . LEU C 3 103 ? 14.218 -21.171 57.512 1.00 86.99 ? 103 LEU C N 1 ATOM 3072 C CA . LEU C 3 103 ? 13.231 -22.242 57.621 1.00 87.94 ? 103 LEU C CA 1 ATOM 3073 C C . LEU C 3 103 ? 13.013 -22.596 59.089 1.00 88.62 ? 103 LEU C C 1 ATOM 3074 O O . LEU C 3 103 ? 13.958 -23.004 59.775 1.00 86.00 ? 103 LEU C O 1 ATOM 3075 C CB . LEU C 3 103 ? 13.704 -23.476 56.847 1.00 88.05 ? 103 LEU C CB 1 ATOM 3076 C CG . LEU C 3 103 ? 12.579 -24.386 56.349 1.00 87.76 ? 103 LEU C CG 1 ATOM 3077 C CD1 . LEU C 3 103 ? 12.008 -23.861 55.039 1.00 88.63 ? 103 LEU C CD1 1 ATOM 3078 C CD2 . LEU C 3 103 ? 13.059 -25.816 56.172 1.00 87.63 ? 103 LEU C CD2 1 ATOM 3079 N N . GLU C 3 104 ? 11.776 -22.423 59.562 1.00 90.57 ? 104 GLU C N 1 ATOM 3080 C CA . GLU C 3 104 ? 11.396 -22.774 60.935 1.00 92.14 ? 104 GLU C CA 1 ATOM 3081 C C . GLU C 3 104 ? 10.294 -23.832 60.938 1.00 88.67 ? 104 GLU C C 1 ATOM 3082 O O . GLU C 3 104 ? 9.369 -23.785 60.123 1.00 81.19 ? 104 GLU C O 1 ATOM 3083 C CB . GLU C 3 104 ? 10.963 -21.528 61.718 1.00 94.41 ? 104 GLU C CB 1 ATOM 3084 C CG . GLU C 3 104 ? 12.132 -20.744 62.304 1.00 95.31 ? 104 GLU C CG 1 ATOM 3085 C CD . GLU C 3 104 ? 11.694 -19.664 63.277 1.00 98.09 ? 104 GLU C CD 1 ATOM 3086 O OE1 . GLU C 3 104 ? 10.796 -18.868 62.921 1.00 100.58 ? 104 GLU C OE1 1 ATOM 3087 O OE2 . GLU C 3 104 ? 12.252 -19.608 64.397 1.00 93.47 ? 104 GLU C OE2 1 ATOM 3088 N N . LEU C 3 105 ? 10.413 -24.782 61.865 1.00 87.74 ? 105 LEU C N 1 ATOM 3089 C CA . LEU C 3 105 ? 9.519 -25.937 61.941 1.00 86.44 ? 105 LEU C CA 1 ATOM 3090 C C . LEU C 3 105 ? 8.315 -25.684 62.843 1.00 82.66 ? 105 LEU C C 1 ATOM 3091 O O . LEU C 3 105 ? 8.458 -25.135 63.938 1.00 83.71 ? 105 LEU C O 1 ATOM 3092 C CB . LEU C 3 105 ? 10.281 -27.165 62.448 1.00 86.81 ? 105 LEU C CB 1 ATOM 3093 C CG . LEU C 3 105 ? 11.384 -27.667 61.516 1.00 90.13 ? 105 LEU C CG 1 ATOM 3094 C CD1 . LEU C 3 105 ? 12.282 -28.670 62.232 1.00 90.85 ? 105 LEU C CD1 1 ATOM 3095 C CD2 . LEU C 3 105 ? 10.793 -28.262 60.244 1.00 90.65 ? 105 LEU C CD2 1 ATOM 3096 N N . LYS C 3 106 ? 7.136 -26.082 62.364 1.00 78.81 ? 106 LYS C N 1 ATOM 3097 C CA . LYS C 3 106 ? 5.929 -26.165 63.188 1.00 76.97 ? 106 LYS C CA 1 ATOM 3098 C C . LYS C 3 106 ? 6.008 -27.428 64.034 1.00 75.67 ? 106 LYS C C 1 ATOM 3099 O O . LYS C 3 106 ? 6.669 -28.401 63.662 1.00 74.00 ? 106 LYS C O 1 ATOM 3100 C CB . LYS C 3 106 ? 4.659 -26.190 62.332 1.00 77.87 ? 106 LYS C CB 1 ATOM 3101 C CG . LYS C 3 106 ? 4.271 -24.844 61.743 1.00 78.96 ? 106 LYS C CG 1 ATOM 3102 C CD . LYS C 3 106 ? 3.448 -24.020 62.726 1.00 82.09 ? 106 LYS C CD 1 ATOM 3103 C CE . LYS C 3 106 ? 3.133 -22.628 62.191 1.00 83.87 ? 106 LYS C CE 1 ATOM 3104 N NZ . LYS C 3 106 ? 2.573 -22.640 60.808 1.00 84.49 ? 106 LYS C NZ 1 ATOM 3105 N N . ARG C 3 107 ? 5.336 -27.404 65.180 1.00 76.16 ? 107 ARG C N 1 ATOM 3106 C CA . ARG C 3 107 ? 5.441 -28.489 66.147 1.00 72.86 ? 107 ARG C CA 1 ATOM 3107 C C . ARG C 3 107 ? 4.285 -28.473 67.134 1.00 72.10 ? 107 ARG C C 1 ATOM 3108 O O . ARG C 3 107 ? 3.520 -27.510 67.211 1.00 69.79 ? 107 ARG C O 1 ATOM 3109 C CB . ARG C 3 107 ? 6.762 -28.370 66.921 1.00 72.88 ? 107 ARG C CB 1 ATOM 3110 C CG . ARG C 3 107 ? 7.535 -29.671 67.049 1.00 73.97 ? 107 ARG C CG 1 ATOM 3111 C CD . ARG C 3 107 ? 8.220 -29.789 68.401 1.00 73.27 ? 107 ARG C CD 1 ATOM 3112 N NE . ARG C 3 107 ? 7.272 -30.235 69.419 1.00 72.47 ? 107 ARG C NE 1 ATOM 3113 C CZ . ARG C 3 107 ? 7.596 -30.700 70.623 1.00 73.49 ? 107 ARG C CZ 1 ATOM 3114 N NH1 . ARG C 3 107 ? 8.868 -30.782 71.022 1.00 74.24 ? 107 ARG C NH1 1 ATOM 3115 N NH2 . ARG C 3 107 ? 6.626 -31.089 71.445 1.00 74.46 ? 107 ARG C NH2 1 ATOM 3116 N N . ALA C 3 108 ? 4.171 -29.562 67.885 1.00 75.34 ? 108 ALA C N 1 ATOM 3117 C CA . ALA C 3 108 ? 3.275 -29.632 69.037 1.00 75.07 ? 108 ALA C CA 1 ATOM 3118 C C . ALA C 3 108 ? 3.827 -28.773 70.172 1.00 72.80 ? 108 ALA C C 1 ATOM 3119 O O . ALA C 3 108 ? 5.045 -28.582 70.276 1.00 73.46 ? 108 ALA C O 1 ATOM 3120 C CB . ALA C 3 108 ? 3.119 -31.074 69.498 1.00 76.51 ? 108 ALA C CB 1 ATOM 3121 N N . ASP C 3 109 ? 2.933 -28.274 71.024 1.00 69.79 ? 109 ASP C N 1 ATOM 3122 C CA . ASP C 3 109 ? 3.332 -27.481 72.190 1.00 67.63 ? 109 ASP C CA 1 ATOM 3123 C C . ASP C 3 109 ? 4.149 -28.327 73.169 1.00 66.04 ? 109 ASP C C 1 ATOM 3124 O O . ASP C 3 109 ? 3.883 -29.518 73.348 1.00 69.20 ? 109 ASP C O 1 ATOM 3125 C CB . ASP C 3 109 ? 2.108 -26.896 72.907 1.00 69.25 ? 109 ASP C CB 1 ATOM 3126 C CG . ASP C 3 109 ? 1.365 -25.870 72.066 1.00 72.63 ? 109 ASP C CG 1 ATOM 3127 O OD1 . ASP C 3 109 ? 1.450 -25.932 70.822 1.00 78.84 ? 109 ASP C OD1 1 ATOM 3128 O OD2 . ASP C 3 109 ? 0.686 -25.000 72.646 1.00 74.15 ? 109 ASP C OD2 1 ATOM 3129 N N . ALA C 3 110 ? 5.152 -27.705 73.778 1.00 63.97 ? 110 ALA C N 1 ATOM 3130 C CA . ALA C 3 110 ? 5.975 -28.339 74.807 1.00 64.50 ? 110 ALA C CA 1 ATOM 3131 C C . ALA C 3 110 ? 6.198 -27.353 75.964 1.00 65.15 ? 110 ALA C C 1 ATOM 3132 O O . ALA C 3 110 ? 6.306 -26.138 75.746 1.00 64.65 ? 110 ALA C O 1 ATOM 3133 C CB . ALA C 3 110 ? 7.301 -28.794 74.218 1.00 63.36 ? 110 ALA C CB 1 ATOM 3134 N N . ALA C 3 111 ? 6.256 -27.884 77.187 1.00 63.60 ? 111 ALA C N 1 ATOM 3135 C CA . ALA C 3 111 ? 6.389 -27.067 78.394 1.00 62.03 ? 111 ALA C CA 1 ATOM 3136 C C . ALA C 3 111 ? 7.851 -26.988 78.842 1.00 59.24 ? 111 ALA C C 1 ATOM 3137 O O . ALA C 3 111 ? 8.566 -27.999 78.815 1.00 56.70 ? 111 ALA C O 1 ATOM 3138 C CB . ALA C 3 111 ? 5.522 -27.621 79.514 1.00 62.09 ? 111 ALA C CB 1 ATOM 3139 N N . PRO C 3 112 ? 8.296 -25.789 79.265 1.00 55.95 ? 112 PRO C N 1 ATOM 3140 C CA . PRO C 3 112 ? 9.698 -25.609 79.629 1.00 55.71 ? 112 PRO C CA 1 ATOM 3141 C C . PRO C 3 112 ? 10.062 -26.271 80.952 1.00 55.86 ? 112 PRO C C 1 ATOM 3142 O O . PRO C 3 112 ? 9.311 -26.147 81.916 1.00 55.89 ? 112 PRO C O 1 ATOM 3143 C CB . PRO C 3 112 ? 9.831 -24.089 79.747 1.00 54.74 ? 112 PRO C CB 1 ATOM 3144 C CG . PRO C 3 112 ? 8.465 -23.625 80.115 1.00 54.22 ? 112 PRO C CG 1 ATOM 3145 C CD . PRO C 3 112 ? 7.532 -24.531 79.382 1.00 53.11 ? 112 PRO C CD 1 ATOM 3146 N N . THR C 3 113 ? 11.196 -26.972 80.980 1.00 57.24 ? 113 THR C N 1 ATOM 3147 C CA . THR C 3 113 ? 11.784 -27.462 82.227 1.00 59.58 ? 113 THR C CA 1 ATOM 3148 C C . THR C 3 113 ? 12.567 -26.311 82.852 1.00 62.14 ? 113 THR C C 1 ATOM 3149 O O . THR C 3 113 ? 13.680 -25.994 82.417 1.00 62.52 ? 113 THR C O 1 ATOM 3150 C CB . THR C 3 113 ? 12.720 -28.676 82.002 1.00 60.01 ? 113 THR C CB 1 ATOM 3151 O OG1 . THR C 3 113 ? 11.951 -29.801 81.564 1.00 60.06 ? 113 THR C OG1 1 ATOM 3152 C CG2 . THR C 3 113 ? 13.467 -29.056 83.286 1.00 59.10 ? 113 THR C CG2 1 ATOM 3153 N N . VAL C 3 114 ? 11.977 -25.703 83.879 1.00 65.49 ? 114 VAL C N 1 ATOM 3154 C CA . VAL C 3 114 ? 12.573 -24.558 84.564 1.00 66.05 ? 114 VAL C CA 1 ATOM 3155 C C . VAL C 3 114 ? 13.415 -25.037 85.745 1.00 67.11 ? 114 VAL C C 1 ATOM 3156 O O . VAL C 3 114 ? 12.938 -25.798 86.583 1.00 70.73 ? 114 VAL C O 1 ATOM 3157 C CB . VAL C 3 114 ? 11.498 -23.572 85.072 1.00 64.87 ? 114 VAL C CB 1 ATOM 3158 C CG1 . VAL C 3 114 ? 12.150 -22.331 85.672 1.00 64.91 ? 114 VAL C CG1 1 ATOM 3159 C CG2 . VAL C 3 114 ? 10.551 -23.184 83.939 1.00 64.76 ? 114 VAL C CG2 1 ATOM 3160 N N . SER C 3 115 ? 14.668 -24.595 85.788 1.00 67.53 ? 115 SER C N 1 ATOM 3161 C CA . SER C 3 115 ? 15.532 -24.773 86.950 1.00 66.69 ? 115 SER C CA 1 ATOM 3162 C C . SER C 3 115 ? 16.223 -23.449 87.243 1.00 66.54 ? 115 SER C C 1 ATOM 3163 O O . SER C 3 115 ? 16.357 -22.602 86.359 1.00 63.20 ? 115 SER C O 1 ATOM 3164 C CB . SER C 3 115 ? 16.557 -25.890 86.715 1.00 66.81 ? 115 SER C CB 1 ATOM 3165 O OG . SER C 3 115 ? 17.421 -25.597 85.632 1.00 65.62 ? 115 SER C OG 1 ATOM 3166 N N . ILE C 3 116 ? 16.653 -23.291 88.493 1.00 70.52 ? 116 ILE C N 1 ATOM 3167 C CA . ILE C 3 116 ? 17.267 -22.053 88.993 1.00 70.32 ? 116 ILE C CA 1 ATOM 3168 C C . ILE C 3 116 ? 18.531 -22.411 89.767 1.00 73.64 ? 116 ILE C C 1 ATOM 3169 O O . ILE C 3 116 ? 18.572 -23.438 90.451 1.00 77.30 ? 116 ILE C O 1 ATOM 3170 C CB . ILE C 3 116 ? 16.285 -21.230 89.877 1.00 68.27 ? 116 ILE C CB 1 ATOM 3171 C CG1 . ILE C 3 116 ? 16.938 -19.926 90.358 1.00 66.66 ? 116 ILE C CG1 1 ATOM 3172 C CG2 . ILE C 3 116 ? 15.780 -22.038 91.070 1.00 67.45 ? 116 ILE C CG2 1 ATOM 3173 C CD1 . ILE C 3 116 ? 15.955 -18.899 90.874 1.00 66.42 ? 116 ILE C CD1 1 ATOM 3174 N N . PHE C 3 117 ? 19.552 -21.562 89.647 1.00 75.47 ? 117 PHE C N 1 ATOM 3175 C CA . PHE C 3 117 ? 20.859 -21.788 90.268 1.00 76.60 ? 117 PHE C CA 1 ATOM 3176 C C . PHE C 3 117 ? 21.302 -20.498 90.958 1.00 80.52 ? 117 PHE C C 1 ATOM 3177 O O . PHE C 3 117 ? 21.355 -19.451 90.308 1.00 84.05 ? 117 PHE C O 1 ATOM 3178 C CB . PHE C 3 117 ? 21.889 -22.202 89.213 1.00 75.57 ? 117 PHE C CB 1 ATOM 3179 C CG . PHE C 3 117 ? 21.400 -23.272 88.279 1.00 75.96 ? 117 PHE C CG 1 ATOM 3180 C CD1 . PHE C 3 117 ? 20.700 -22.936 87.123 1.00 76.92 ? 117 PHE C CD1 1 ATOM 3181 C CD2 . PHE C 3 117 ? 21.618 -24.614 88.560 1.00 78.24 ? 117 PHE C CD2 1 ATOM 3182 C CE1 . PHE C 3 117 ? 20.235 -23.918 86.262 1.00 77.49 ? 117 PHE C CE1 1 ATOM 3183 C CE2 . PHE C 3 117 ? 21.158 -25.604 87.701 1.00 80.40 ? 117 PHE C CE2 1 ATOM 3184 C CZ . PHE C 3 117 ? 20.464 -25.255 86.549 1.00 79.84 ? 117 PHE C CZ 1 ATOM 3185 N N . PRO C 3 118 ? 21.611 -20.560 92.273 1.00 84.17 ? 118 PRO C N 1 ATOM 3186 C CA . PRO C 3 118 ? 22.056 -19.360 92.984 1.00 83.18 ? 118 PRO C CA 1 ATOM 3187 C C . PRO C 3 118 ? 23.516 -19.034 92.665 1.00 82.82 ? 118 PRO C C 1 ATOM 3188 O O . PRO C 3 118 ? 24.243 -19.909 92.189 1.00 79.92 ? 118 PRO C O 1 ATOM 3189 C CB . PRO C 3 118 ? 21.895 -19.753 94.452 1.00 83.35 ? 118 PRO C CB 1 ATOM 3190 C CG . PRO C 3 118 ? 22.144 -21.219 94.466 1.00 84.22 ? 118 PRO C CG 1 ATOM 3191 C CD . PRO C 3 118 ? 21.646 -21.749 93.148 1.00 85.59 ? 118 PRO C CD 1 ATOM 3192 N N . PRO C 3 119 ? 23.948 -17.786 92.929 1.00 86.91 ? 119 PRO C N 1 ATOM 3193 C CA . PRO C 3 119 ? 25.315 -17.387 92.592 1.00 92.74 ? 119 PRO C CA 1 ATOM 3194 C C . PRO C 3 119 ? 26.357 -18.161 93.400 1.00 98.53 ? 119 PRO C C 1 ATOM 3195 O O . PRO C 3 119 ? 26.175 -18.376 94.601 1.00 102.71 ? 119 PRO C O 1 ATOM 3196 C CB . PRO C 3 119 ? 25.343 -15.895 92.938 1.00 92.00 ? 119 PRO C CB 1 ATOM 3197 C CG . PRO C 3 119 ? 24.297 -15.732 93.976 1.00 91.00 ? 119 PRO C CG 1 ATOM 3198 C CD . PRO C 3 119 ? 23.216 -16.705 93.611 1.00 88.18 ? 119 PRO C CD 1 ATOM 3199 N N . SER C 3 120 ? 27.431 -18.572 92.727 1.00 103.00 ? 120 SER C N 1 ATOM 3200 C CA . SER C 3 120 ? 28.435 -19.466 93.304 1.00 105.86 ? 120 SER C CA 1 ATOM 3201 C C . SER C 3 120 ? 29.385 -18.740 94.257 1.00 111.79 ? 120 SER C C 1 ATOM 3202 O O . SER C 3 120 ? 29.371 -17.509 94.352 1.00 111.04 ? 120 SER C O 1 ATOM 3203 C CB . SER C 3 120 ? 29.237 -20.126 92.184 1.00 104.60 ? 120 SER C CB 1 ATOM 3204 O OG . SER C 3 120 ? 29.823 -19.143 91.349 1.00 106.52 ? 120 SER C OG 1 ATOM 3205 N N . THR C 3 121 ? 30.208 -19.525 94.950 1.00 115.59 ? 121 THR C N 1 ATOM 3206 C CA . THR C 3 121 ? 31.215 -19.010 95.886 1.00 115.35 ? 121 THR C CA 1 ATOM 3207 C C . THR C 3 121 ? 32.296 -18.167 95.196 1.00 112.71 ? 121 THR C C 1 ATOM 3208 O O . THR C 3 121 ? 32.691 -17.119 95.716 1.00 108.82 ? 121 THR C O 1 ATOM 3209 C CB . THR C 3 121 ? 31.898 -20.160 96.662 1.00 117.10 ? 121 THR C CB 1 ATOM 3210 O OG1 . THR C 3 121 ? 32.378 -21.153 95.743 1.00 115.43 ? 121 THR C OG1 1 ATOM 3211 C CG2 . THR C 3 121 ? 30.918 -20.803 97.638 1.00 116.82 ? 121 THR C CG2 1 ATOM 3212 N N . GLU C 3 122 ? 32.757 -18.628 94.031 1.00 111.10 ? 122 GLU C N 1 ATOM 3213 C CA . GLU C 3 122 ? 33.785 -17.925 93.248 1.00 112.78 ? 122 GLU C CA 1 ATOM 3214 C C . GLU C 3 122 ? 33.373 -16.496 92.891 1.00 116.73 ? 122 GLU C C 1 ATOM 3215 O O . GLU C 3 122 ? 34.146 -15.558 93.090 1.00 122.93 ? 122 GLU C O 1 ATOM 3216 C CB . GLU C 3 122 ? 34.117 -18.679 91.952 1.00 110.47 ? 122 GLU C CB 1 ATOM 3217 C CG . GLU C 3 122 ? 34.905 -19.969 92.127 1.00 108.97 ? 122 GLU C CG 1 ATOM 3218 C CD . GLU C 3 122 ? 34.029 -21.208 92.114 1.00 108.85 ? 122 GLU C CD 1 ATOM 3219 O OE1 . GLU C 3 122 ? 34.325 -22.130 91.325 1.00 108.24 ? 122 GLU C OE1 1 ATOM 3220 O OE2 . GLU C 3 122 ? 33.041 -21.252 92.883 1.00 106.36 ? 122 GLU C OE2 1 ATOM 3221 N N . GLN C 3 123 ? 32.159 -16.339 92.368 1.00 118.91 ? 123 GLN C N 1 ATOM 3222 C CA . GLN C 3 123 ? 31.665 -15.024 91.944 1.00 124.67 ? 123 GLN C CA 1 ATOM 3223 C C . GLN C 3 123 ? 31.472 -14.059 93.118 1.00 127.65 ? 123 GLN C C 1 ATOM 3224 O O . GLN C 3 123 ? 31.756 -12.865 92.991 1.00 124.53 ? 123 GLN C O 1 ATOM 3225 C CB . GLN C 3 123 ? 30.359 -15.162 91.161 1.00 126.18 ? 123 GLN C CB 1 ATOM 3226 C CG . GLN C 3 123 ? 29.985 -13.905 90.382 1.00 125.01 ? 123 GLN C CG 1 ATOM 3227 C CD . GLN C 3 123 ? 28.706 -14.042 89.577 1.00 123.45 ? 123 GLN C CD 1 ATOM 3228 O OE1 . GLN C 3 123 ? 28.254 -13.077 88.962 1.00 123.68 ? 123 GLN C OE1 1 ATOM 3229 N NE2 . GLN C 3 123 ? 28.116 -15.235 89.576 1.00 120.61 ? 123 GLN C NE2 1 ATOM 3230 N N . LEU C 3 124 ? 30.991 -14.582 94.246 1.00 132.53 ? 124 LEU C N 1 ATOM 3231 C CA . LEU C 3 124 ? 30.829 -13.796 95.480 1.00 133.73 ? 124 LEU C CA 1 ATOM 3232 C C . LEU C 3 124 ? 32.144 -13.188 95.985 1.00 131.58 ? 124 LEU C C 1 ATOM 3233 O O . LEU C 3 124 ? 32.138 -12.108 96.580 1.00 127.61 ? 124 LEU C O 1 ATOM 3234 C CB . LEU C 3 124 ? 30.198 -14.654 96.585 1.00 136.98 ? 124 LEU C CB 1 ATOM 3235 C CG . LEU C 3 124 ? 28.727 -15.033 96.369 1.00 138.27 ? 124 LEU C CG 1 ATOM 3236 C CD1 . LEU C 3 124 ? 28.338 -16.244 97.210 1.00 136.93 ? 124 LEU C CD1 1 ATOM 3237 C CD2 . LEU C 3 124 ? 27.811 -13.852 96.663 1.00 139.66 ? 124 LEU C CD2 1 ATOM 3238 N N . ALA C 3 125 ? 33.255 -13.885 95.745 1.00 129.57 ? 125 ALA C N 1 ATOM 3239 C CA . ALA C 3 125 ? 34.589 -13.380 96.086 1.00 128.56 ? 125 ALA C CA 1 ATOM 3240 C C . ALA C 3 125 ? 35.000 -12.167 95.243 1.00 126.72 ? 125 ALA C C 1 ATOM 3241 O O . ALA C 3 125 ? 35.621 -11.237 95.762 1.00 126.48 ? 125 ALA C O 1 ATOM 3242 C CB . ALA C 3 125 ? 35.625 -14.487 95.952 1.00 129.12 ? 125 ALA C CB 1 ATOM 3243 N N . THR C 3 126 ? 34.636 -12.170 93.959 1.00 123.82 ? 126 THR C N 1 ATOM 3244 C CA . THR C 3 126 ? 35.009 -11.094 93.023 1.00 122.58 ? 126 THR C CA 1 ATOM 3245 C C . THR C 3 126 ? 34.236 -9.762 93.183 1.00 118.32 ? 126 THR C C 1 ATOM 3246 O O . THR C 3 126 ? 34.512 -8.799 92.461 1.00 111.66 ? 126 THR C O 1 ATOM 3247 C CB . THR C 3 126 ? 34.882 -11.577 91.558 1.00 123.48 ? 126 THR C CB 1 ATOM 3248 O OG1 . THR C 3 126 ? 33.559 -12.075 91.325 1.00 124.65 ? 126 THR C OG1 1 ATOM 3249 C CG2 . THR C 3 126 ? 35.887 -12.685 91.269 1.00 121.97 ? 126 THR C CG2 1 ATOM 3250 N N . GLY C 3 127 ? 33.287 -9.703 94.120 1.00 116.49 ? 127 GLY C N 1 ATOM 3251 C CA . GLY C 3 127 ? 32.493 -8.500 94.355 1.00 113.95 ? 127 GLY C CA 1 ATOM 3252 C C . GLY C 3 127 ? 31.371 -8.374 93.343 1.00 113.38 ? 127 GLY C C 1 ATOM 3253 O O . GLY C 3 127 ? 31.084 -7.277 92.863 1.00 118.35 ? 127 GLY C O 1 ATOM 3254 N N . GLY C 3 128 ? 30.740 -9.503 93.024 1.00 107.59 ? 128 GLY C N 1 ATOM 3255 C CA . GLY C 3 128 ? 29.634 -9.551 92.067 1.00 104.91 ? 128 GLY C CA 1 ATOM 3256 C C . GLY C 3 128 ? 28.730 -10.742 92.323 1.00 103.72 ? 128 GLY C C 1 ATOM 3257 O O . GLY C 3 128 ? 29.076 -11.637 93.098 1.00 105.43 ? 128 GLY C O 1 ATOM 3258 N N . ALA C 3 129 ? 27.567 -10.748 91.675 1.00 101.19 ? 129 ALA C N 1 ATOM 3259 C CA . ALA C 3 129 ? 26.605 -11.846 91.814 1.00 96.90 ? 129 ALA C CA 1 ATOM 3260 C C . ALA C 3 129 ? 25.681 -11.944 90.599 1.00 90.80 ? 129 ALA C C 1 ATOM 3261 O O . ALA C 3 129 ? 25.143 -10.935 90.134 1.00 85.31 ? 129 ALA C O 1 ATOM 3262 C CB . ALA C 3 129 ? 25.791 -11.673 93.087 1.00 98.26 ? 129 ALA C CB 1 ATOM 3263 N N . SER C 3 130 ? 25.507 -13.165 90.095 1.00 83.95 ? 130 SER C N 1 ATOM 3264 C CA . SER C 3 130 ? 24.643 -13.434 88.952 1.00 80.85 ? 130 SER C CA 1 ATOM 3265 C C . SER C 3 130 ? 23.746 -14.626 89.264 1.00 75.66 ? 130 SER C C 1 ATOM 3266 O O . SER C 3 130 ? 24.242 -15.732 89.488 1.00 73.59 ? 130 SER C O 1 ATOM 3267 C CB . SER C 3 130 ? 25.471 -13.702 87.687 1.00 79.71 ? 130 SER C CB 1 ATOM 3268 O OG . SER C 3 130 ? 26.065 -12.505 87.204 1.00 75.10 ? 130 SER C OG 1 ATOM 3269 N N . VAL C 3 131 ? 22.435 -14.388 89.290 1.00 72.23 ? 131 VAL C N 1 ATOM 3270 C CA . VAL C 3 131 ? 21.442 -15.449 89.497 1.00 72.46 ? 131 VAL C CA 1 ATOM 3271 C C . VAL C 3 131 ? 20.921 -15.848 88.123 1.00 71.51 ? 131 VAL C C 1 ATOM 3272 O O . VAL C 3 131 ? 20.500 -14.978 87.361 1.00 71.80 ? 131 VAL C O 1 ATOM 3273 C CB . VAL C 3 131 ? 20.246 -14.982 90.364 1.00 71.14 ? 131 VAL C CB 1 ATOM 3274 C CG1 . VAL C 3 131 ? 19.468 -16.188 90.877 1.00 70.27 ? 131 VAL C CG1 1 ATOM 3275 C CG2 . VAL C 3 131 ? 20.709 -14.109 91.525 1.00 71.67 ? 131 VAL C CG2 1 ATOM 3276 N N . VAL C 3 132 ? 20.933 -17.145 87.810 1.00 70.76 ? 132 VAL C N 1 ATOM 3277 C CA . VAL C 3 132 ? 20.553 -17.621 86.470 1.00 74.99 ? 132 VAL C CA 1 ATOM 3278 C C . VAL C 3 132 ? 19.342 -18.562 86.499 1.00 73.28 ? 132 VAL C C 1 ATOM 3279 O O . VAL C 3 132 ? 19.148 -19.317 87.454 1.00 72.04 ? 132 VAL C O 1 ATOM 3280 C CB . VAL C 3 132 ? 21.758 -18.274 85.735 1.00 78.80 ? 132 VAL C CB 1 ATOM 3281 C CG1 . VAL C 3 132 ? 22.058 -19.667 86.271 1.00 80.66 ? 132 VAL C CG1 1 ATOM 3282 C CG2 . VAL C 3 132 ? 21.526 -18.317 84.224 1.00 80.29 ? 132 VAL C CG2 1 ATOM 3283 N N . CYS C 3 133 ? 18.543 -18.497 85.435 1.00 72.95 ? 133 CYS C N 1 ATOM 3284 C CA . CYS C 3 133 ? 17.325 -19.291 85.289 1.00 72.70 ? 133 CYS C CA 1 ATOM 3285 C C . CYS C 3 133 ? 17.262 -19.843 83.865 1.00 69.57 ? 133 CYS C C 1 ATOM 3286 O O . CYS C 3 133 ? 17.288 -19.072 82.905 1.00 65.57 ? 133 CYS C O 1 ATOM 3287 C CB . CYS C 3 133 ? 16.106 -18.413 85.577 1.00 74.05 ? 133 CYS C CB 1 ATOM 3288 S SG . CYS C 3 133 ? 14.555 -19.298 85.829 1.00 74.77 ? 133 CYS C SG 1 ATOM 3289 N N . LEU C 3 134 ? 17.189 -21.170 83.743 1.00 67.42 ? 134 LEU C N 1 ATOM 3290 C CA . LEU C 3 134 ? 17.219 -21.852 82.450 1.00 68.23 ? 134 LEU C CA 1 ATOM 3291 C C . LEU C 3 134 ? 15.880 -22.512 82.162 1.00 66.91 ? 134 LEU C C 1 ATOM 3292 O O . LEU C 3 134 ? 15.426 -23.349 82.934 1.00 68.33 ? 134 LEU C O 1 ATOM 3293 C CB . LEU C 3 134 ? 18.309 -22.922 82.441 1.00 69.10 ? 134 LEU C CB 1 ATOM 3294 C CG . LEU C 3 134 ? 19.711 -22.474 82.851 1.00 72.11 ? 134 LEU C CG 1 ATOM 3295 C CD1 . LEU C 3 134 ? 20.648 -23.666 82.803 1.00 73.39 ? 134 LEU C CD1 1 ATOM 3296 C CD2 . LEU C 3 134 ? 20.229 -21.354 81.962 1.00 73.58 ? 134 LEU C CD2 1 ATOM 3297 N N . MET C 3 135 ? 15.270 -22.137 81.040 1.00 65.99 ? 135 MET C N 1 ATOM 3298 C CA . MET C 3 135 ? 13.993 -22.690 80.598 1.00 65.60 ? 135 MET C CA 1 ATOM 3299 C C . MET C 3 135 ? 14.226 -23.516 79.337 1.00 67.78 ? 135 MET C C 1 ATOM 3300 O O . MET C 3 135 ? 14.247 -22.977 78.229 1.00 67.96 ? 135 MET C O 1 ATOM 3301 C CB . MET C 3 135 ? 13.018 -21.553 80.322 1.00 63.60 ? 135 MET C CB 1 ATOM 3302 C CG . MET C 3 135 ? 12.650 -20.763 81.566 1.00 62.40 ? 135 MET C CG 1 ATOM 3303 S SD . MET C 3 135 ? 12.611 -18.989 81.282 1.00 60.25 ? 135 MET C SD 1 ATOM 3304 C CE . MET C 3 135 ? 14.364 -18.633 81.198 1.00 60.52 ? 135 MET C CE 1 ATOM 3305 N N . ASN C 3 136 ? 14.397 -24.825 79.521 1.00 67.58 ? 136 ASN C N 1 ATOM 3306 C CA . ASN C 3 136 ? 14.828 -25.728 78.452 1.00 65.04 ? 136 ASN C CA 1 ATOM 3307 C C . ASN C 3 136 ? 13.672 -26.459 77.781 1.00 62.80 ? 136 ASN C C 1 ATOM 3308 O O . ASN C 3 136 ? 12.739 -26.902 78.448 1.00 59.54 ? 136 ASN C O 1 ATOM 3309 C CB . ASN C 3 136 ? 15.828 -26.750 79.003 1.00 64.97 ? 136 ASN C CB 1 ATOM 3310 C CG . ASN C 3 136 ? 17.149 -26.118 79.395 1.00 66.61 ? 136 ASN C CG 1 ATOM 3311 O OD1 . ASN C 3 136 ? 17.706 -25.302 78.656 1.00 68.62 ? 136 ASN C OD1 1 ATOM 3312 N ND2 . ASN C 3 136 ? 17.663 -26.494 80.560 1.00 68.54 ? 136 ASN C ND2 1 ATOM 3313 N N . ASN C 3 137 ? 13.758 -26.566 76.453 1.00 62.48 ? 137 ASN C N 1 ATOM 3314 C CA . ASN C 3 137 ? 12.907 -27.446 75.640 1.00 63.36 ? 137 ASN C CA 1 ATOM 3315 C C . ASN C 3 137 ? 11.418 -27.085 75.686 1.00 63.49 ? 137 ASN C C 1 ATOM 3316 O O . ASN C 3 137 ? 10.634 -27.734 76.383 1.00 69.31 ? 137 ASN C O 1 ATOM 3317 C CB . ASN C 3 137 ? 13.120 -28.919 76.031 1.00 61.89 ? 137 ASN C CB 1 ATOM 3318 C CG . ASN C 3 137 ? 14.585 -29.295 76.107 1.00 63.48 ? 137 ASN C CG 1 ATOM 3319 O OD1 . ASN C 3 137 ? 15.369 -28.977 75.215 1.00 65.30 ? 137 ASN C OD1 1 ATOM 3320 N ND2 . ASN C 3 137 ? 14.965 -29.969 77.185 1.00 67.67 ? 137 ASN C ND2 1 ATOM 3321 N N . PHE C 3 138 ? 11.035 -26.059 74.932 1.00 60.00 ? 138 PHE C N 1 ATOM 3322 C CA . PHE C 3 138 ? 9.633 -25.658 74.839 1.00 60.19 ? 138 PHE C CA 1 ATOM 3323 C C . PHE C 3 138 ? 9.219 -25.211 73.435 1.00 58.86 ? 138 PHE C C 1 ATOM 3324 O O . PHE C 3 138 ? 10.063 -25.002 72.567 1.00 59.51 ? 138 PHE C O 1 ATOM 3325 C CB . PHE C 3 138 ? 9.345 -24.563 75.872 1.00 61.81 ? 138 PHE C CB 1 ATOM 3326 C CG . PHE C 3 138 ? 10.144 -23.300 75.672 1.00 62.11 ? 138 PHE C CG 1 ATOM 3327 C CD1 . PHE C 3 138 ? 11.418 -23.154 76.230 1.00 62.21 ? 138 PHE C CD1 1 ATOM 3328 C CD2 . PHE C 3 138 ? 9.609 -22.241 74.946 1.00 60.92 ? 138 PHE C CD2 1 ATOM 3329 C CE1 . PHE C 3 138 ? 12.134 -21.977 76.052 1.00 61.28 ? 138 PHE C CE1 1 ATOM 3330 C CE2 . PHE C 3 138 ? 10.322 -21.068 74.766 1.00 60.86 ? 138 PHE C CE2 1 ATOM 3331 C CZ . PHE C 3 138 ? 11.586 -20.936 75.320 1.00 61.86 ? 138 PHE C CZ 1 ATOM 3332 N N . TYR C 3 139 ? 7.909 -25.086 73.230 1.00 58.05 ? 139 TYR C N 1 ATOM 3333 C CA . TYR C 3 139 ? 7.335 -24.591 71.975 1.00 59.49 ? 139 TYR C CA 1 ATOM 3334 C C . TYR C 3 139 ? 5.913 -24.092 72.248 1.00 60.35 ? 139 TYR C C 1 ATOM 3335 O O . TYR C 3 139 ? 5.202 -24.745 73.006 1.00 63.03 ? 139 TYR C O 1 ATOM 3336 C CB . TYR C 3 139 ? 7.301 -25.702 70.914 1.00 59.67 ? 139 TYR C CB 1 ATOM 3337 C CG . TYR C 3 139 ? 6.858 -25.210 69.553 1.00 59.21 ? 139 TYR C CG 1 ATOM 3338 C CD1 . TYR C 3 139 ? 5.501 -25.089 69.240 1.00 59.67 ? 139 TYR C CD1 1 ATOM 3339 C CD2 . TYR C 3 139 ? 7.793 -24.829 68.587 1.00 59.31 ? 139 TYR C CD2 1 ATOM 3340 C CE1 . TYR C 3 139 ? 5.088 -24.613 68.004 1.00 60.86 ? 139 TYR C CE1 1 ATOM 3341 C CE2 . TYR C 3 139 ? 7.390 -24.360 67.341 1.00 59.23 ? 139 TYR C CE2 1 ATOM 3342 C CZ . TYR C 3 139 ? 6.037 -24.252 67.055 1.00 60.30 ? 139 TYR C CZ 1 ATOM 3343 O OH . TYR C 3 139 ? 5.617 -23.785 65.832 1.00 59.26 ? 139 TYR C OH 1 ATOM 3344 N N . PRO C 3 140 ? 5.474 -22.966 71.667 1.00 65.91 ? 140 PRO C N 1 ATOM 3345 C CA . PRO C 3 140 ? 6.258 -22.092 70.774 1.00 69.89 ? 140 PRO C CA 1 ATOM 3346 C C . PRO C 3 140 ? 7.275 -21.217 71.511 1.00 73.00 ? 140 PRO C C 1 ATOM 3347 O O . PRO C 3 140 ? 7.510 -21.422 72.699 1.00 70.15 ? 140 PRO C O 1 ATOM 3348 C CB . PRO C 3 140 ? 5.179 -21.211 70.100 1.00 70.23 ? 140 PRO C CB 1 ATOM 3349 C CG . PRO C 3 140 ? 3.852 -21.664 70.630 1.00 68.56 ? 140 PRO C CG 1 ATOM 3350 C CD . PRO C 3 140 ? 4.108 -22.452 71.872 1.00 67.59 ? 140 PRO C CD 1 ATOM 3351 N N . ARG C 3 141 ? 7.881 -20.263 70.801 1.00 79.86 ? 141 ARG C N 1 ATOM 3352 C CA . ARG C 3 141 ? 8.728 -19.237 71.425 1.00 84.53 ? 141 ARG C CA 1 ATOM 3353 C C . ARG C 3 141 ? 7.845 -18.063 71.886 1.00 84.51 ? 141 ARG C C 1 ATOM 3354 O O . ARG C 3 141 ? 7.898 -16.961 71.339 1.00 88.84 ? 141 ARG C O 1 ATOM 3355 C CB . ARG C 3 141 ? 9.841 -18.786 70.463 1.00 86.71 ? 141 ARG C CB 1 ATOM 3356 C CG . ARG C 3 141 ? 10.817 -17.798 71.081 1.00 91.04 ? 141 ARG C CG 1 ATOM 3357 C CD . ARG C 3 141 ? 12.230 -17.898 70.529 1.00 93.11 ? 141 ARG C CD 1 ATOM 3358 N NE . ARG C 3 141 ? 12.353 -17.597 69.104 1.00 93.16 ? 141 ARG C NE 1 ATOM 3359 C CZ . ARG C 3 141 ? 13.512 -17.530 68.441 1.00 91.36 ? 141 ARG C CZ 1 ATOM 3360 N NH1 . ARG C 3 141 ? 14.677 -17.743 69.058 1.00 87.62 ? 141 ARG C NH1 1 ATOM 3361 N NH2 . ARG C 3 141 ? 13.510 -17.249 67.141 1.00 93.03 ? 141 ARG C NH2 1 ATOM 3362 N N . ASP C 3 142 ? 7.018 -18.331 72.891 1.00 84.10 ? 142 ASP C N 1 ATOM 3363 C CA . ASP C 3 142 ? 6.072 -17.361 73.435 1.00 86.44 ? 142 ASP C CA 1 ATOM 3364 C C . ASP C 3 142 ? 6.141 -17.511 74.935 1.00 83.38 ? 142 ASP C C 1 ATOM 3365 O O . ASP C 3 142 ? 5.272 -18.133 75.557 1.00 84.19 ? 142 ASP C O 1 ATOM 3366 C CB . ASP C 3 142 ? 4.646 -17.622 72.932 1.00 91.75 ? 142 ASP C CB 1 ATOM 3367 C CG . ASP C 3 142 ? 4.486 -17.351 71.447 1.00 98.70 ? 142 ASP C CG 1 ATOM 3368 O OD1 . ASP C 3 142 ? 5.070 -16.365 70.946 1.00 102.36 ? 142 ASP C OD1 1 ATOM 3369 O OD2 . ASP C 3 142 ? 3.762 -18.120 70.776 1.00 105.77 ? 142 ASP C OD2 1 ATOM 3370 N N . ILE C 3 143 ? 7.197 -16.932 75.499 1.00 79.44 ? 143 ILE C N 1 ATOM 3371 C CA . ILE C 3 143 ? 7.582 -17.151 76.888 1.00 74.67 ? 143 ILE C CA 1 ATOM 3372 C C . ILE C 3 143 ? 7.956 -15.815 77.545 1.00 72.28 ? 143 ILE C C 1 ATOM 3373 O O . ILE C 3 143 ? 8.654 -14.997 76.947 1.00 74.09 ? 143 ILE C O 1 ATOM 3374 C CB . ILE C 3 143 ? 8.732 -18.190 76.968 1.00 72.22 ? 143 ILE C CB 1 ATOM 3375 C CG1 . ILE C 3 143 ? 8.980 -18.635 78.413 1.00 73.73 ? 143 ILE C CG1 1 ATOM 3376 C CG2 . ILE C 3 143 ? 10.015 -17.665 76.333 1.00 71.35 ? 143 ILE C CG2 1 ATOM 3377 C CD1 . ILE C 3 143 ? 9.863 -19.863 78.524 1.00 72.17 ? 143 ILE C CD1 1 ATOM 3378 N N . SER C 3 144 ? 7.460 -15.590 78.757 1.00 69.44 ? 144 SER C N 1 ATOM 3379 C CA . SER C 3 144 ? 7.799 -14.402 79.536 1.00 67.84 ? 144 SER C CA 1 ATOM 3380 C C . SER C 3 144 ? 8.401 -14.854 80.854 1.00 66.11 ? 144 SER C C 1 ATOM 3381 O O . SER C 3 144 ? 7.817 -15.692 81.545 1.00 66.30 ? 144 SER C O 1 ATOM 3382 C CB . SER C 3 144 ? 6.556 -13.544 79.785 1.00 67.01 ? 144 SER C CB 1 ATOM 3383 O OG . SER C 3 144 ? 6.194 -12.819 78.620 1.00 66.96 ? 144 SER C OG 1 ATOM 3384 N N . VAL C 3 145 ? 9.565 -14.298 81.192 1.00 63.83 ? 145 VAL C N 1 ATOM 3385 C CA . VAL C 3 145 ? 10.234 -14.578 82.466 1.00 61.99 ? 145 VAL C CA 1 ATOM 3386 C C . VAL C 3 145 ? 10.099 -13.355 83.356 1.00 61.08 ? 145 VAL C C 1 ATOM 3387 O O . VAL C 3 145 ? 10.029 -12.229 82.869 1.00 62.21 ? 145 VAL C O 1 ATOM 3388 C CB . VAL C 3 145 ? 11.735 -14.895 82.304 1.00 61.12 ? 145 VAL C CB 1 ATOM 3389 C CG1 . VAL C 3 145 ? 12.221 -15.747 83.469 1.00 60.62 ? 145 VAL C CG1 1 ATOM 3390 C CG2 . VAL C 3 145 ? 12.009 -15.604 80.988 1.00 63.43 ? 145 VAL C CG2 1 ATOM 3391 N N . LYS C 3 146 ? 10.060 -13.584 84.661 1.00 62.75 ? 146 LYS C N 1 ATOM 3392 C CA . LYS C 3 146 ? 9.978 -12.502 85.632 1.00 64.39 ? 146 LYS C CA 1 ATOM 3393 C C . LYS C 3 146 ? 10.803 -12.858 86.863 1.00 64.01 ? 146 LYS C C 1 ATOM 3394 O O . LYS C 3 146 ? 10.689 -13.966 87.387 1.00 65.77 ? 146 LYS C O 1 ATOM 3395 C CB . LYS C 3 146 ? 8.515 -12.262 86.006 1.00 66.28 ? 146 LYS C CB 1 ATOM 3396 C CG . LYS C 3 146 ? 8.207 -10.858 86.502 1.00 68.44 ? 146 LYS C CG 1 ATOM 3397 C CD . LYS C 3 146 ? 6.810 -10.418 86.088 1.00 71.50 ? 146 LYS C CD 1 ATOM 3398 C CE . LYS C 3 146 ? 6.761 -9.970 84.631 1.00 73.17 ? 146 LYS C CE 1 ATOM 3399 N NZ . LYS C 3 146 ? 5.429 -9.407 84.269 1.00 74.22 ? 146 LYS C NZ 1 ATOM 3400 N N . TRP C 3 147 ? 11.644 -11.924 87.298 1.00 63.17 ? 147 TRP C N 1 ATOM 3401 C CA . TRP C 3 147 ? 12.451 -12.084 88.509 1.00 64.49 ? 147 TRP C CA 1 ATOM 3402 C C . TRP C 3 147 ? 11.785 -11.369 89.670 1.00 64.26 ? 147 TRP C C 1 ATOM 3403 O O . TRP C 3 147 ? 11.120 -10.361 89.467 1.00 62.47 ? 147 TRP C O 1 ATOM 3404 C CB . TRP C 3 147 ? 13.857 -11.534 88.285 1.00 64.13 ? 147 TRP C CB 1 ATOM 3405 C CG . TRP C 3 147 ? 14.644 -12.411 87.405 1.00 65.46 ? 147 TRP C CG 1 ATOM 3406 C CD1 . TRP C 3 147 ? 14.708 -12.365 86.047 1.00 66.09 ? 147 TRP C CD1 1 ATOM 3407 C CD2 . TRP C 3 147 ? 15.462 -13.508 87.812 1.00 67.17 ? 147 TRP C CD2 1 ATOM 3408 N NE1 . TRP C 3 147 ? 15.531 -13.359 85.578 1.00 66.81 ? 147 TRP C NE1 1 ATOM 3409 C CE2 . TRP C 3 147 ? 16.010 -14.076 86.641 1.00 66.59 ? 147 TRP C CE2 1 ATOM 3410 C CE3 . TRP C 3 147 ? 15.796 -14.061 89.056 1.00 66.95 ? 147 TRP C CE3 1 ATOM 3411 C CZ2 . TRP C 3 147 ? 16.877 -15.172 86.675 1.00 66.61 ? 147 TRP C CZ2 1 ATOM 3412 C CZ3 . TRP C 3 147 ? 16.654 -15.150 89.092 1.00 67.23 ? 147 TRP C CZ3 1 ATOM 3413 C CH2 . TRP C 3 147 ? 17.186 -15.696 87.904 1.00 68.08 ? 147 TRP C CH2 1 ATOM 3414 N N . LYS C 3 148 ? 11.962 -11.899 90.878 1.00 66.90 ? 148 LYS C N 1 ATOM 3415 C CA . LYS C 3 148 ? 11.398 -11.298 92.086 1.00 71.25 ? 148 LYS C CA 1 ATOM 3416 C C . LYS C 3 148 ? 12.389 -11.307 93.249 1.00 73.88 ? 148 LYS C C 1 ATOM 3417 O O . LYS C 3 148 ? 13.007 -12.333 93.545 1.00 73.53 ? 148 LYS C O 1 ATOM 3418 C CB . LYS C 3 148 ? 10.108 -12.014 92.480 1.00 73.50 ? 148 LYS C CB 1 ATOM 3419 C CG . LYS C 3 148 ? 8.933 -11.665 91.593 1.00 75.63 ? 148 LYS C CG 1 ATOM 3420 C CD . LYS C 3 148 ? 7.631 -12.222 92.143 1.00 77.93 ? 148 LYS C CD 1 ATOM 3421 C CE . LYS C 3 148 ? 6.568 -12.292 91.058 1.00 80.35 ? 148 LYS C CE 1 ATOM 3422 N NZ . LYS C 3 148 ? 6.383 -11.008 90.322 1.00 80.21 ? 148 LYS C NZ 1 ATOM 3423 N N . ILE C 3 149 ? 12.530 -10.144 93.889 1.00 78.11 ? 149 ILE C N 1 ATOM 3424 C CA . ILE C 3 149 ? 13.366 -9.971 95.085 1.00 78.24 ? 149 ILE C CA 1 ATOM 3425 C C . ILE C 3 149 ? 12.448 -9.613 96.257 1.00 73.91 ? 149 ILE C C 1 ATOM 3426 O O . ILE C 3 149 ? 11.807 -8.563 96.262 1.00 69.79 ? 149 ILE C O 1 ATOM 3427 C CB . ILE C 3 149 ? 14.524 -8.946 94.873 1.00 82.47 ? 149 ILE C CB 1 ATOM 3428 C CG1 . ILE C 3 149 ? 14.030 -7.504 94.582 1.00 84.69 ? 149 ILE C CG1 1 ATOM 3429 C CG2 . ILE C 3 149 ? 15.438 -9.425 93.747 1.00 83.06 ? 149 ILE C CG2 1 ATOM 3430 C CD1 . ILE C 3 149 ? 13.971 -6.575 95.785 1.00 82.00 ? 149 ILE C CD1 1 ATOM 3431 N N . ASP C 3 150 ? 12.349 -10.528 97.221 1.00 74.24 ? 150 ASP C N 1 ATOM 3432 C CA . ASP C 3 150 ? 11.435 -10.382 98.357 1.00 74.68 ? 150 ASP C CA 1 ATOM 3433 C C . ASP C 3 150 ? 10.021 -10.008 97.899 1.00 72.36 ? 150 ASP C C 1 ATOM 3434 O O . ASP C 3 150 ? 9.417 -9.081 98.433 1.00 72.27 ? 150 ASP C O 1 ATOM 3435 C CB . ASP C 3 150 ? 11.971 -9.339 99.362 1.00 75.44 ? 150 ASP C CB 1 ATOM 3436 C CG . ASP C 3 150 ? 13.318 -9.721 99.969 1.00 73.81 ? 150 ASP C CG 1 ATOM 3437 O OD1 . ASP C 3 150 ? 13.621 -10.932 100.106 1.00 71.44 ? 150 ASP C OD1 1 ATOM 3438 O OD2 . ASP C 3 150 ? 14.075 -8.794 100.332 1.00 72.76 ? 150 ASP C OD2 1 ATOM 3439 N N . GLY C 3 151 ? 9.517 -10.703 96.880 1.00 73.85 ? 151 GLY C N 1 ATOM 3440 C CA . GLY C 3 151 ? 8.150 -10.490 96.393 1.00 73.83 ? 151 GLY C CA 1 ATOM 3441 C C . GLY C 3 151 ? 7.930 -9.432 95.318 1.00 72.86 ? 151 GLY C C 1 ATOM 3442 O O . GLY C 3 151 ? 6.998 -9.573 94.525 1.00 76.87 ? 151 GLY C O 1 ATOM 3443 N N . THR C 3 152 ? 8.740 -8.369 95.292 1.00 71.41 ? 152 THR C N 1 ATOM 3444 C CA . THR C 3 152 ? 8.643 -7.340 94.241 1.00 72.81 ? 152 THR C CA 1 ATOM 3445 C C . THR C 3 152 ? 9.617 -7.648 93.117 1.00 72.39 ? 152 THR C C 1 ATOM 3446 O O . THR C 3 152 ? 10.700 -8.186 93.358 1.00 69.80 ? 152 THR C O 1 ATOM 3447 C CB . THR C 3 152 ? 8.943 -5.922 94.762 1.00 72.73 ? 152 THR C CB 1 ATOM 3448 O OG1 . THR C 3 152 ? 10.289 -5.859 95.245 1.00 73.08 ? 152 THR C OG1 1 ATOM 3449 C CG2 . THR C 3 152 ? 7.967 -5.535 95.875 1.00 73.69 ? 152 THR C CG2 1 ATOM 3450 N N . GLU C 3 153 ? 9.239 -7.290 91.894 1.00 72.06 ? 153 GLU C N 1 ATOM 3451 C CA . GLU C 3 153 ? 10.025 -7.691 90.734 1.00 74.76 ? 153 GLU C CA 1 ATOM 3452 C C . GLU C 3 153 ? 11.216 -6.775 90.479 1.00 75.82 ? 153 GLU C C 1 ATOM 3453 O O . GLU C 3 153 ? 11.271 -5.655 90.993 1.00 74.66 ? 153 GLU C O 1 ATOM 3454 C CB . GLU C 3 153 ? 9.162 -7.852 89.476 1.00 75.34 ? 153 GLU C CB 1 ATOM 3455 C CG . GLU C 3 153 ? 8.453 -6.601 88.986 1.00 76.61 ? 153 GLU C CG 1 ATOM 3456 C CD . GLU C 3 153 ? 8.037 -6.677 87.528 1.00 77.89 ? 153 GLU C CD 1 ATOM 3457 O OE1 . GLU C 3 153 ? 8.336 -7.681 86.842 1.00 75.21 ? 153 GLU C OE1 1 ATOM 3458 O OE2 . GLU C 3 153 ? 7.405 -5.707 87.063 1.00 82.34 ? 153 GLU C OE2 1 ATOM 3459 N N . ARG C 3 154 ? 12.168 -7.284 89.696 1.00 77.24 ? 154 ARG C N 1 ATOM 3460 C CA . ARG C 3 154 ? 13.365 -6.542 89.307 1.00 79.75 ? 154 ARG C CA 1 ATOM 3461 C C . ARG C 3 154 ? 13.614 -6.696 87.812 1.00 77.14 ? 154 ARG C C 1 ATOM 3462 O O . ARG C 3 154 ? 14.116 -7.723 87.364 1.00 74.45 ? 154 ARG C O 1 ATOM 3463 C CB . ARG C 3 154 ? 14.584 -7.032 90.096 1.00 83.99 ? 154 ARG C CB 1 ATOM 3464 C CG . ARG C 3 154 ? 15.873 -6.260 89.816 1.00 85.90 ? 154 ARG C CG 1 ATOM 3465 C CD . ARG C 3 154 ? 15.899 -4.923 90.536 1.00 88.70 ? 154 ARG C CD 1 ATOM 3466 N NE . ARG C 3 154 ? 16.052 -5.117 91.978 1.00 93.14 ? 154 ARG C NE 1 ATOM 3467 C CZ . ARG C 3 154 ? 17.191 -5.430 92.600 1.00 93.80 ? 154 ARG C CZ 1 ATOM 3468 N NH1 . ARG C 3 154 ? 18.331 -5.588 91.927 1.00 94.34 ? 154 ARG C NH1 1 ATOM 3469 N NH2 . ARG C 3 154 ? 17.191 -5.587 93.920 1.00 95.07 ? 154 ARG C NH2 1 ATOM 3470 N N . ARG C 3 155 ? 13.244 -5.665 87.057 1.00 80.91 ? 155 ARG C N 1 ATOM 3471 C CA . ARG C 3 155 ? 13.568 -5.558 85.628 1.00 84.84 ? 155 ARG C CA 1 ATOM 3472 C C . ARG C 3 155 ? 15.037 -5.163 85.368 1.00 84.78 ? 155 ARG C C 1 ATOM 3473 O O . ARG C 3 155 ? 15.590 -5.494 84.313 1.00 85.24 ? 155 ARG C O 1 ATOM 3474 C CB . ARG C 3 155 ? 12.595 -4.588 84.914 1.00 88.30 ? 155 ARG C CB 1 ATOM 3475 C CG . ARG C 3 155 ? 12.896 -3.081 84.993 1.00 91.88 ? 155 ARG C CG 1 ATOM 3476 C CD . ARG C 3 155 ? 12.716 -2.488 86.388 1.00 93.75 ? 155 ARG C CD 1 ATOM 3477 N NE . ARG C 3 155 ? 12.552 -1.029 86.370 1.00 95.13 ? 155 ARG C NE 1 ATOM 3478 C CZ . ARG C 3 155 ? 12.271 -0.272 87.436 1.00 93.27 ? 155 ARG C CZ 1 ATOM 3479 N NH1 . ARG C 3 155 ? 12.125 -0.811 88.645 1.00 92.76 ? 155 ARG C NH1 1 ATOM 3480 N NH2 . ARG C 3 155 ? 12.134 1.044 87.293 1.00 92.90 ? 155 ARG C NH2 1 ATOM 3481 N N . ASP C 3 156 ? 15.656 -4.466 86.325 1.00 82.52 ? 156 ASP C N 1 ATOM 3482 C CA . ASP C 3 156 ? 16.995 -3.885 86.148 1.00 79.02 ? 156 ASP C CA 1 ATOM 3483 C C . ASP C 3 156 ? 18.086 -4.956 86.225 1.00 73.62 ? 156 ASP C C 1 ATOM 3484 O O . ASP C 3 156 ? 18.046 -5.817 87.103 1.00 69.90 ? 156 ASP C O 1 ATOM 3485 C CB . ASP C 3 156 ? 17.261 -2.802 87.211 1.00 83.04 ? 156 ASP C CB 1 ATOM 3486 C CG . ASP C 3 156 ? 16.269 -1.631 87.138 1.00 87.32 ? 156 ASP C CG 1 ATOM 3487 O OD1 . ASP C 3 156 ? 16.137 -1.005 86.060 1.00 85.40 ? 156 ASP C OD1 1 ATOM 3488 O OD2 . ASP C 3 156 ? 15.629 -1.328 88.171 1.00 88.90 ? 156 ASP C OD2 1 ATOM 3489 N N . GLY C 3 157 ? 19.049 -4.898 85.303 1.00 70.26 ? 157 GLY C N 1 ATOM 3490 C CA . GLY C 3 157 ? 20.205 -5.807 85.305 1.00 67.47 ? 157 GLY C CA 1 ATOM 3491 C C . GLY C 3 157 ? 19.935 -7.242 84.872 1.00 67.77 ? 157 GLY C C 1 ATOM 3492 O O . GLY C 3 157 ? 20.620 -8.170 85.325 1.00 65.83 ? 157 GLY C O 1 ATOM 3493 N N . VAL C 3 158 ? 18.956 -7.420 83.981 1.00 67.01 ? 158 VAL C N 1 ATOM 3494 C CA . VAL C 3 158 ? 18.561 -8.738 83.475 1.00 64.64 ? 158 VAL C CA 1 ATOM 3495 C C . VAL C 3 158 ? 18.949 -8.841 82.002 1.00 62.99 ? 158 VAL C C 1 ATOM 3496 O O . VAL C 3 158 ? 18.758 -7.894 81.242 1.00 62.02 ? 158 VAL C O 1 ATOM 3497 C CB . VAL C 3 158 ? 17.042 -8.973 83.638 1.00 63.79 ? 158 VAL C CB 1 ATOM 3498 C CG1 . VAL C 3 158 ? 16.637 -10.338 83.087 1.00 63.32 ? 158 VAL C CG1 1 ATOM 3499 C CG2 . VAL C 3 158 ? 16.640 -8.851 85.103 1.00 63.89 ? 158 VAL C CG2 1 ATOM 3500 N N . LEU C 3 159 ? 19.491 -9.995 81.616 1.00 63.45 ? 159 LEU C N 1 ATOM 3501 C CA . LEU C 3 159 ? 19.919 -10.255 80.243 1.00 63.10 ? 159 LEU C CA 1 ATOM 3502 C C . LEU C 3 159 ? 19.429 -11.629 79.786 1.00 63.84 ? 159 LEU C C 1 ATOM 3503 O O . LEU C 3 159 ? 19.984 -12.647 80.198 1.00 60.77 ? 159 LEU C O 1 ATOM 3504 C CB . LEU C 3 159 ? 21.444 -10.189 80.145 1.00 62.75 ? 159 LEU C CB 1 ATOM 3505 C CG . LEU C 3 159 ? 22.102 -8.831 80.405 1.00 63.66 ? 159 LEU C CG 1 ATOM 3506 C CD1 . LEU C 3 159 ? 23.611 -9.023 80.473 1.00 66.45 ? 159 LEU C CD1 1 ATOM 3507 C CD2 . LEU C 3 159 ? 21.743 -7.793 79.352 1.00 60.91 ? 159 LEU C CD2 1 ATOM 3508 N N . ASP C 3 160 ? 18.395 -11.633 78.935 1.00 67.92 ? 160 ASP C N 1 ATOM 3509 C CA . ASP C 3 160 ? 17.796 -12.859 78.381 1.00 68.56 ? 160 ASP C CA 1 ATOM 3510 C C . ASP C 3 160 ? 18.473 -13.249 77.071 1.00 67.28 ? 160 ASP C C 1 ATOM 3511 O O . ASP C 3 160 ? 18.961 -12.389 76.344 1.00 66.36 ? 160 ASP C O 1 ATOM 3512 C CB . ASP C 3 160 ? 16.300 -12.668 78.097 1.00 70.88 ? 160 ASP C CB 1 ATOM 3513 C CG . ASP C 3 160 ? 15.527 -12.112 79.286 1.00 75.59 ? 160 ASP C CG 1 ATOM 3514 O OD1 . ASP C 3 160 ? 15.636 -10.896 79.550 1.00 81.45 ? 160 ASP C OD1 1 ATOM 3515 O OD2 . ASP C 3 160 ? 14.783 -12.875 79.939 1.00 78.31 ? 160 ASP C OD2 1 ATOM 3516 N N . SER C 3 161 ? 18.486 -14.547 76.770 1.00 68.30 ? 161 SER C N 1 ATOM 3517 C CA . SER C 3 161 ? 18.952 -15.045 75.469 1.00 69.00 ? 161 SER C CA 1 ATOM 3518 C C . SER C 3 161 ? 18.259 -16.353 75.080 1.00 70.38 ? 161 SER C C 1 ATOM 3519 O O . SER C 3 161 ? 18.398 -17.363 75.779 1.00 69.21 ? 161 SER C O 1 ATOM 3520 C CB . SER C 3 161 ? 20.466 -15.250 75.477 1.00 68.08 ? 161 SER C CB 1 ATOM 3521 O OG . SER C 3 161 ? 20.831 -16.375 76.249 1.00 67.63 ? 161 SER C OG 1 ATOM 3522 N N . VAL C 3 162 ? 17.537 -16.325 73.956 1.00 71.54 ? 162 VAL C N 1 ATOM 3523 C CA . VAL C 3 162 ? 16.811 -17.490 73.440 1.00 69.21 ? 162 VAL C CA 1 ATOM 3524 C C . VAL C 3 162 ? 17.591 -18.091 72.270 1.00 73.24 ? 162 VAL C C 1 ATOM 3525 O O . VAL C 3 162 ? 18.065 -17.354 71.403 1.00 76.33 ? 162 VAL C O 1 ATOM 3526 C CB . VAL C 3 162 ? 15.389 -17.136 72.934 1.00 66.09 ? 162 VAL C CB 1 ATOM 3527 C CG1 . VAL C 3 162 ? 14.501 -18.378 72.974 1.00 68.06 ? 162 VAL C CG1 1 ATOM 3528 C CG2 . VAL C 3 162 ? 14.765 -15.996 73.734 1.00 64.97 ? 162 VAL C CG2 1 ATOM 3529 N N . THR C 3 163 ? 17.714 -19.419 72.239 1.00 74.58 ? 163 THR C N 1 ATOM 3530 C CA . THR C 3 163 ? 18.402 -20.116 71.143 1.00 76.83 ? 163 THR C CA 1 ATOM 3531 C C . THR C 3 163 ? 17.527 -20.225 69.880 1.00 81.85 ? 163 THR C C 1 ATOM 3532 O O . THR C 3 163 ? 16.337 -19.882 69.898 1.00 80.49 ? 163 THR C O 1 ATOM 3533 C CB . THR C 3 163 ? 18.826 -21.545 71.551 1.00 73.86 ? 163 THR C CB 1 ATOM 3534 O OG1 . THR C 3 163 ? 17.675 -22.285 71.972 1.00 75.23 ? 163 THR C OG1 1 ATOM 3535 C CG2 . THR C 3 163 ? 19.858 -21.522 72.665 1.00 71.39 ? 163 THR C CG2 1 ATOM 3536 N N . ASP C 3 164 ? 18.147 -20.692 68.792 1.00 86.60 ? 164 ASP C N 1 ATOM 3537 C CA . ASP C 3 164 ? 17.443 -21.096 67.565 1.00 87.38 ? 164 ASP C CA 1 ATOM 3538 C C . ASP C 3 164 ? 16.973 -22.548 67.718 1.00 85.04 ? 164 ASP C C 1 ATOM 3539 O O . ASP C 3 164 ? 17.606 -23.329 68.446 1.00 79.22 ? 164 ASP C O 1 ATOM 3540 C CB . ASP C 3 164 ? 18.367 -20.974 66.346 1.00 91.77 ? 164 ASP C CB 1 ATOM 3541 C CG . ASP C 3 164 ? 18.901 -19.555 66.149 1.00 96.53 ? 164 ASP C CG 1 ATOM 3542 O OD1 . ASP C 3 164 ? 18.086 -18.609 66.105 1.00 98.62 ? 164 ASP C OD1 1 ATOM 3543 O OD2 . ASP C 3 164 ? 20.137 -19.387 66.030 1.00 98.37 ? 164 ASP C OD2 1 ATOM 3544 N N . GLN C 3 165 ? 15.878 -22.902 67.030 1.00 82.93 ? 165 GLN C N 1 ATOM 3545 C CA . GLN C 3 165 ? 15.245 -24.236 67.154 1.00 82.42 ? 165 GLN C CA 1 ATOM 3546 C C . GLN C 3 165 ? 16.265 -25.370 67.125 1.00 84.04 ? 165 GLN C C 1 ATOM 3547 O O . GLN C 3 165 ? 17.165 -25.374 66.285 1.00 87.58 ? 165 GLN C O 1 ATOM 3548 C CB . GLN C 3 165 ? 14.207 -24.475 66.046 1.00 78.14 ? 165 GLN C CB 1 ATOM 3549 C CG . GLN C 3 165 ? 12.919 -23.698 66.233 1.00 77.32 ? 165 GLN C CG 1 ATOM 3550 C CD . GLN C 3 165 ? 11.808 -24.126 65.290 1.00 77.44 ? 165 GLN C CD 1 ATOM 3551 O OE1 . GLN C 3 165 ? 11.767 -23.710 64.129 1.00 76.18 ? 165 GLN C OE1 1 ATOM 3552 N NE2 . GLN C 3 165 ? 10.882 -24.939 65.793 1.00 76.77 ? 165 GLN C NE2 1 ATOM 3553 N N . ASP C 3 166 ? 16.121 -26.320 68.047 1.00 87.41 ? 166 ASP C N 1 ATOM 3554 C CA . ASP C 3 166 ? 17.052 -27.443 68.152 1.00 92.61 ? 166 ASP C CA 1 ATOM 3555 C C . ASP C 3 166 ? 16.931 -28.348 66.921 1.00 96.91 ? 166 ASP C C 1 ATOM 3556 O O . ASP C 3 166 ? 15.829 -28.566 66.407 1.00 93.34 ? 166 ASP C O 1 ATOM 3557 C CB . ASP C 3 166 ? 16.794 -28.245 69.436 1.00 92.58 ? 166 ASP C CB 1 ATOM 3558 C CG . ASP C 3 166 ? 17.911 -29.226 69.751 1.00 92.57 ? 166 ASP C CG 1 ATOM 3559 O OD1 . ASP C 3 166 ? 19.082 -28.799 69.822 1.00 92.46 ? 166 ASP C OD1 1 ATOM 3560 O OD2 . ASP C 3 166 ? 17.616 -30.426 69.935 1.00 95.27 ? 166 ASP C OD2 1 ATOM 3561 N N . SER C 3 167 ? 18.074 -28.849 66.452 1.00 100.78 ? 167 SER C N 1 ATOM 3562 C CA . SER C 3 167 ? 18.136 -29.751 65.296 1.00 99.87 ? 167 SER C CA 1 ATOM 3563 C C . SER C 3 167 ? 17.328 -31.026 65.526 1.00 101.28 ? 167 SER C C 1 ATOM 3564 O O . SER C 3 167 ? 16.669 -31.521 64.611 1.00 99.11 ? 167 SER C O 1 ATOM 3565 C CB . SER C 3 167 ? 19.590 -30.141 65.002 1.00 100.99 ? 167 SER C CB 1 ATOM 3566 O OG . SER C 3 167 ? 20.447 -29.014 65.014 1.00 101.37 ? 167 SER C OG 1 ATOM 3567 N N . LYS C 3 168 ? 17.378 -31.530 66.760 1.00 103.80 ? 168 LYS C N 1 ATOM 3568 C CA . LYS C 3 168 ? 16.810 -32.829 67.115 1.00 103.24 ? 168 LYS C CA 1 ATOM 3569 C C . LYS C 3 168 ? 15.288 -32.765 67.261 1.00 99.41 ? 168 LYS C C 1 ATOM 3570 O O . LYS C 3 168 ? 14.577 -33.425 66.504 1.00 95.21 ? 168 LYS C O 1 ATOM 3571 C CB . LYS C 3 168 ? 17.474 -33.368 68.401 1.00 105.87 ? 168 LYS C CB 1 ATOM 3572 C CG . LYS C 3 168 ? 17.669 -34.880 68.433 1.00 107.75 ? 168 LYS C CG 1 ATOM 3573 C CD . LYS C 3 168 ? 18.747 -35.286 69.434 1.00 109.78 ? 168 LYS C CD 1 ATOM 3574 C CE . LYS C 3 168 ? 19.161 -36.741 69.266 1.00 108.96 ? 168 LYS C CE 1 ATOM 3575 N NZ . LYS C 3 168 ? 18.051 -37.691 69.555 1.00 107.65 ? 168 LYS C NZ 1 ATOM 3576 N N . ASP C 3 169 ? 14.798 -31.945 68.197 1.00 99.63 ? 169 ASP C N 1 ATOM 3577 C CA . ASP C 3 169 ? 13.372 -31.969 68.611 1.00 99.71 ? 169 ASP C CA 1 ATOM 3578 C C . ASP C 3 169 ? 12.539 -30.691 68.350 1.00 94.81 ? 169 ASP C C 1 ATOM 3579 O O . ASP C 3 169 ? 11.416 -30.586 68.843 1.00 91.78 ? 169 ASP C O 1 ATOM 3580 C CB . ASP C 3 169 ? 13.247 -32.409 70.091 1.00 102.50 ? 169 ASP C CB 1 ATOM 3581 C CG . ASP C 3 169 ? 13.958 -31.471 71.072 1.00 105.51 ? 169 ASP C CG 1 ATOM 3582 O OD1 . ASP C 3 169 ? 14.293 -30.320 70.711 1.00 107.15 ? 169 ASP C OD1 1 ATOM 3583 O OD2 . ASP C 3 169 ? 14.183 -31.900 72.226 1.00 104.11 ? 169 ASP C OD2 1 ATOM 3584 N N . SER C 3 170 ? 13.081 -29.742 67.581 1.00 93.48 ? 170 SER C N 1 ATOM 3585 C CA . SER C 3 170 ? 12.365 -28.511 67.165 1.00 92.42 ? 170 SER C CA 1 ATOM 3586 C C . SER C 3 170 ? 11.896 -27.586 68.313 1.00 89.23 ? 170 SER C C 1 ATOM 3587 O O . SER C 3 170 ? 10.911 -26.852 68.161 1.00 87.72 ? 170 SER C O 1 ATOM 3588 C CB . SER C 3 170 ? 11.170 -28.855 66.252 1.00 92.32 ? 170 SER C CB 1 ATOM 3589 O OG . SER C 3 170 ? 11.536 -29.735 65.205 1.00 94.15 ? 170 SER C OG 1 ATOM 3590 N N . THR C 3 171 ? 12.607 -27.612 69.442 1.00 85.38 ? 171 THR C N 1 ATOM 3591 C CA . THR C 3 171 ? 12.272 -26.774 70.601 1.00 82.39 ? 171 THR C CA 1 ATOM 3592 C C . THR C 3 171 ? 13.238 -25.605 70.738 1.00 78.76 ? 171 THR C C 1 ATOM 3593 O O . THR C 3 171 ? 14.391 -25.680 70.304 1.00 79.69 ? 171 THR C O 1 ATOM 3594 C CB . THR C 3 171 ? 12.296 -27.570 71.929 1.00 82.41 ? 171 THR C CB 1 ATOM 3595 O OG1 . THR C 3 171 ? 13.611 -28.093 72.176 1.00 79.48 ? 171 THR C OG1 1 ATOM 3596 C CG2 . THR C 3 171 ? 11.274 -28.703 71.907 1.00 82.53 ? 171 THR C CG2 1 ATOM 3597 N N . TYR C 3 172 ? 12.750 -24.532 71.349 1.00 74.48 ? 172 TYR C N 1 ATOM 3598 C CA . TYR C 3 172 ? 13.585 -23.410 71.752 1.00 72.74 ? 172 TYR C CA 1 ATOM 3599 C C . TYR C 3 172 ? 14.010 -23.605 73.208 1.00 70.03 ? 172 TYR C C 1 ATOM 3600 O O . TYR C 3 172 ? 13.512 -24.494 73.907 1.00 70.34 ? 172 TYR C O 1 ATOM 3601 C CB . TYR C 3 172 ? 12.821 -22.098 71.606 1.00 74.62 ? 172 TYR C CB 1 ATOM 3602 C CG . TYR C 3 172 ? 12.245 -21.843 70.224 1.00 76.26 ? 172 TYR C CG 1 ATOM 3603 C CD1 . TYR C 3 172 ? 12.998 -21.203 69.241 1.00 74.30 ? 172 TYR C CD1 1 ATOM 3604 C CD2 . TYR C 3 172 ? 10.933 -22.225 69.907 1.00 77.78 ? 172 TYR C CD2 1 ATOM 3605 C CE1 . TYR C 3 172 ? 12.467 -20.951 67.982 1.00 75.39 ? 172 TYR C CE1 1 ATOM 3606 C CE2 . TYR C 3 172 ? 10.394 -21.982 68.646 1.00 75.62 ? 172 TYR C CE2 1 ATOM 3607 C CZ . TYR C 3 172 ? 11.163 -21.343 67.685 1.00 75.19 ? 172 TYR C CZ 1 ATOM 3608 O OH . TYR C 3 172 ? 10.643 -21.099 66.429 1.00 70.33 ? 172 TYR C OH 1 ATOM 3609 N N . SER C 3 173 ? 14.945 -22.773 73.649 1.00 66.61 ? 173 SER C N 1 ATOM 3610 C CA . SER C 3 173 ? 15.442 -22.788 75.025 1.00 64.90 ? 173 SER C CA 1 ATOM 3611 C C . SER C 3 173 ? 15.889 -21.376 75.386 1.00 67.92 ? 173 SER C C 1 ATOM 3612 O O . SER C 3 173 ? 16.511 -20.706 74.565 1.00 73.10 ? 173 SER C O 1 ATOM 3613 C CB . SER C 3 173 ? 16.609 -23.764 75.174 1.00 60.51 ? 173 SER C CB 1 ATOM 3614 O OG . SER C 3 173 ? 16.165 -25.100 75.046 1.00 58.44 ? 173 SER C OG 1 ATOM 3615 N N . MET C 3 174 ? 15.579 -20.931 76.603 1.00 68.60 ? 174 MET C N 1 ATOM 3616 C CA . MET C 3 174 ? 15.916 -19.574 77.047 1.00 68.15 ? 174 MET C CA 1 ATOM 3617 C C . MET C 3 174 ? 16.756 -19.616 78.318 1.00 66.78 ? 174 MET C C 1 ATOM 3618 O O . MET C 3 174 ? 16.691 -20.573 79.095 1.00 64.52 ? 174 MET C O 1 ATOM 3619 C CB . MET C 3 174 ? 14.639 -18.764 77.280 1.00 68.90 ? 174 MET C CB 1 ATOM 3620 C CG . MET C 3 174 ? 14.839 -17.267 77.474 1.00 69.06 ? 174 MET C CG 1 ATOM 3621 S SD . MET C 3 174 ? 13.234 -16.435 77.533 1.00 73.86 ? 174 MET C SD 1 ATOM 3622 C CE . MET C 3 174 ? 13.600 -14.766 76.985 1.00 74.03 ? 174 MET C CE 1 ATOM 3623 N N . SER C 3 175 ? 17.553 -18.566 78.501 1.00 66.05 ? 175 SER C N 1 ATOM 3624 C CA . SER C 3 175 ? 18.362 -18.373 79.697 1.00 64.64 ? 175 SER C CA 1 ATOM 3625 C C . SER C 3 175 ? 18.427 -16.879 80.015 1.00 63.81 ? 175 SER C C 1 ATOM 3626 O O . SER C 3 175 ? 18.854 -16.094 79.169 1.00 64.18 ? 175 SER C O 1 ATOM 3627 C CB . SER C 3 175 ? 19.770 -18.920 79.473 1.00 63.20 ? 175 SER C CB 1 ATOM 3628 O OG . SER C 3 175 ? 20.633 -18.589 80.549 1.00 65.45 ? 175 SER C OG 1 ATOM 3629 N N . SER C 3 176 ? 17.989 -16.489 81.213 1.00 62.54 ? 176 SER C N 1 ATOM 3630 C CA . SER C 3 176 ? 18.158 -15.108 81.678 1.00 63.29 ? 176 SER C CA 1 ATOM 3631 C C . SER C 3 176 ? 19.009 -15.075 82.943 1.00 61.71 ? 176 SER C C 1 ATOM 3632 O O . SER C 3 176 ? 18.923 -15.982 83.778 1.00 57.42 ? 176 SER C O 1 ATOM 3633 C CB . SER C 3 176 ? 16.808 -14.407 81.888 1.00 62.98 ? 176 SER C CB 1 ATOM 3634 O OG . SER C 3 176 ? 16.244 -14.689 83.151 1.00 63.43 ? 176 SER C OG 1 ATOM 3635 N N . THR C 3 177 ? 19.835 -14.032 83.063 1.00 61.15 ? 177 THR C N 1 ATOM 3636 C CA . THR C 3 177 ? 20.725 -13.872 84.211 1.00 60.38 ? 177 THR C CA 1 ATOM 3637 C C . THR C 3 177 ? 20.583 -12.457 84.802 1.00 60.92 ? 177 THR C C 1 ATOM 3638 O O . THR C 3 177 ? 20.812 -11.444 84.124 1.00 55.66 ? 177 THR C O 1 ATOM 3639 C CB . THR C 3 177 ? 22.210 -14.240 83.895 1.00 59.22 ? 177 THR C CB 1 ATOM 3640 O OG1 . THR C 3 177 ? 23.081 -13.133 84.163 1.00 60.15 ? 177 THR C OG1 1 ATOM 3641 C CG2 . THR C 3 177 ? 22.399 -14.724 82.447 1.00 59.45 ? 177 THR C CG2 1 ATOM 3642 N N . LEU C 3 178 ? 20.174 -12.422 86.071 1.00 63.60 ? 178 LEU C N 1 ATOM 3643 C CA . LEU C 3 178 ? 20.086 -11.200 86.868 1.00 65.70 ? 178 LEU C CA 1 ATOM 3644 C C . LEU C 3 178 ? 21.467 -10.910 87.465 1.00 67.26 ? 178 LEU C C 1 ATOM 3645 O O . LEU C 3 178 ? 21.971 -11.708 88.259 1.00 65.32 ? 178 LEU C O 1 ATOM 3646 C CB . LEU C 3 178 ? 19.045 -11.396 87.982 1.00 65.60 ? 178 LEU C CB 1 ATOM 3647 C CG . LEU C 3 178 ? 18.845 -10.329 89.062 1.00 65.67 ? 178 LEU C CG 1 ATOM 3648 C CD1 . LEU C 3 178 ? 18.340 -9.031 88.461 1.00 66.10 ? 178 LEU C CD1 1 ATOM 3649 C CD2 . LEU C 3 178 ? 17.875 -10.845 90.116 1.00 66.48 ? 178 LEU C CD2 1 ATOM 3650 N N . SER C 3 179 ? 22.072 -9.784 87.080 1.00 69.65 ? 179 SER C N 1 ATOM 3651 C CA . SER C 3 179 ? 23.407 -9.397 87.565 1.00 73.96 ? 179 SER C CA 1 ATOM 3652 C C . SER C 3 179 ? 23.330 -8.319 88.664 1.00 76.14 ? 179 SER C C 1 ATOM 3653 O O . SER C 3 179 ? 22.733 -7.260 88.470 1.00 77.02 ? 179 SER C O 1 ATOM 3654 C CB . SER C 3 179 ? 24.292 -8.934 86.399 1.00 74.67 ? 179 SER C CB 1 ATOM 3655 O OG . SER C 3 179 ? 23.636 -7.983 85.579 1.00 76.95 ? 179 SER C OG 1 ATOM 3656 N N . LEU C 3 180 ? 23.950 -8.608 89.809 1.00 78.80 ? 180 LEU C N 1 ATOM 3657 C CA . LEU C 3 180 ? 23.874 -7.774 91.015 1.00 79.56 ? 180 LEU C CA 1 ATOM 3658 C C . LEU C 3 180 ? 25.257 -7.596 91.616 1.00 79.62 ? 180 LEU C C 1 ATOM 3659 O O . LEU C 3 180 ? 26.142 -8.430 91.398 1.00 80.21 ? 180 LEU C O 1 ATOM 3660 C CB . LEU C 3 180 ? 23.020 -8.469 92.079 1.00 80.36 ? 180 LEU C CB 1 ATOM 3661 C CG . LEU C 3 180 ? 21.674 -9.069 91.680 1.00 81.39 ? 180 LEU C CG 1 ATOM 3662 C CD1 . LEU C 3 180 ? 21.201 -10.064 92.729 1.00 80.02 ? 180 LEU C CD1 1 ATOM 3663 C CD2 . LEU C 3 180 ? 20.656 -7.960 91.479 1.00 83.62 ? 180 LEU C CD2 1 ATOM 3664 N N . THR C 3 181 ? 25.430 -6.538 92.407 1.00 76.64 ? 181 THR C N 1 ATOM 3665 C CA . THR C 3 181 ? 26.591 -6.436 93.297 1.00 76.25 ? 181 THR C CA 1 ATOM 3666 C C . THR C 3 181 ? 26.394 -7.412 94.457 1.00 77.94 ? 181 THR C C 1 ATOM 3667 O O . THR C 3 181 ? 25.261 -7.788 94.765 1.00 79.71 ? 181 THR C O 1 ATOM 3668 C CB . THR C 3 181 ? 26.783 -5.016 93.868 1.00 75.12 ? 181 THR C CB 1 ATOM 3669 O OG1 . THR C 3 181 ? 25.612 -4.616 94.588 1.00 74.61 ? 181 THR C OG1 1 ATOM 3670 C CG2 . THR C 3 181 ? 27.058 -4.013 92.762 1.00 75.45 ? 181 THR C CG2 1 ATOM 3671 N N . LYS C 3 182 ? 27.493 -7.825 95.088 1.00 80.28 ? 182 LYS C N 1 ATOM 3672 C CA . LYS C 3 182 ? 27.432 -8.628 96.324 1.00 81.48 ? 182 LYS C CA 1 ATOM 3673 C C . LYS C 3 182 ? 26.698 -7.856 97.436 1.00 79.19 ? 182 LYS C C 1 ATOM 3674 O O . LYS C 3 182 ? 25.978 -8.454 98.242 1.00 73.67 ? 182 LYS C O 1 ATOM 3675 C CB . LYS C 3 182 ? 28.841 -9.019 96.790 1.00 83.37 ? 182 LYS C CB 1 ATOM 3676 C CG . LYS C 3 182 ? 28.880 -10.082 97.884 1.00 85.18 ? 182 LYS C CG 1 ATOM 3677 C CD . LYS C 3 182 ? 30.262 -10.194 98.521 1.00 86.77 ? 182 LYS C CD 1 ATOM 3678 C CE . LYS C 3 182 ? 30.531 -9.100 99.551 1.00 86.36 ? 182 LYS C CE 1 ATOM 3679 N NZ . LYS C 3 182 ? 29.672 -9.200 100.764 1.00 84.27 ? 182 LYS C NZ 1 ATOM 3680 N N . ALA C 3 183 ? 26.888 -6.534 97.457 1.00 79.75 ? 183 ALA C N 1 ATOM 3681 C CA . ALA C 3 183 ? 26.128 -5.622 98.317 1.00 79.71 ? 183 ALA C CA 1 ATOM 3682 C C . ALA C 3 183 ? 24.619 -5.762 98.117 1.00 79.76 ? 183 ALA C C 1 ATOM 3683 O O . ALA C 3 183 ? 23.883 -5.934 99.088 1.00 81.82 ? 183 ALA C O 1 ATOM 3684 C CB . ALA C 3 183 ? 26.556 -4.180 98.061 1.00 79.43 ? 183 ALA C CB 1 ATOM 3685 N N . ASP C 3 184 ? 24.177 -5.704 96.860 1.00 78.85 ? 184 ASP C N 1 ATOM 3686 C CA . ASP C 3 184 ? 22.747 -5.796 96.509 1.00 79.27 ? 184 ASP C CA 1 ATOM 3687 C C . ASP C 3 184 ? 22.166 -7.224 96.611 1.00 76.31 ? 184 ASP C C 1 ATOM 3688 O O . ASP C 3 184 ? 20.949 -7.386 96.738 1.00 73.80 ? 184 ASP C O 1 ATOM 3689 C CB . ASP C 3 184 ? 22.525 -5.235 95.090 1.00 83.14 ? 184 ASP C CB 1 ATOM 3690 C CG . ASP C 3 184 ? 21.066 -4.858 94.800 1.00 85.13 ? 184 ASP C CG 1 ATOM 3691 O OD1 . ASP C 3 184 ? 20.221 -4.866 95.720 1.00 86.27 ? 184 ASP C OD1 1 ATOM 3692 O OD2 . ASP C 3 184 ? 20.770 -4.531 93.626 1.00 84.85 ? 184 ASP C OD2 1 ATOM 3693 N N . TYR C 3 185 ? 23.022 -8.247 96.553 1.00 74.54 ? 185 TYR C N 1 ATOM 3694 C CA . TYR C 3 185 ? 22.562 -9.638 96.589 1.00 73.21 ? 185 TYR C CA 1 ATOM 3695 C C . TYR C 3 185 ? 21.976 -10.017 97.945 1.00 77.34 ? 185 TYR C C 1 ATOM 3696 O O . TYR C 3 185 ? 20.787 -10.305 98.038 1.00 78.84 ? 185 TYR C O 1 ATOM 3697 C CB . TYR C 3 185 ? 23.680 -10.608 96.213 1.00 70.26 ? 185 TYR C CB 1 ATOM 3698 C CG . TYR C 3 185 ? 23.274 -12.062 96.326 1.00 69.22 ? 185 TYR C CG 1 ATOM 3699 C CD1 . TYR C 3 185 ? 22.221 -12.572 95.568 1.00 69.21 ? 185 TYR C CD1 1 ATOM 3700 C CD2 . TYR C 3 185 ? 23.941 -12.931 97.192 1.00 68.88 ? 185 TYR C CD2 1 ATOM 3701 C CE1 . TYR C 3 185 ? 21.845 -13.908 95.665 1.00 69.23 ? 185 TYR C CE1 1 ATOM 3702 C CE2 . TYR C 3 185 ? 23.575 -14.267 97.297 1.00 68.23 ? 185 TYR C CE2 1 ATOM 3703 C CZ . TYR C 3 185 ? 22.526 -14.753 96.535 1.00 68.37 ? 185 TYR C CZ 1 ATOM 3704 O OH . TYR C 3 185 ? 22.163 -16.077 96.637 1.00 64.42 ? 185 TYR C OH 1 ATOM 3705 N N . GLU C 3 186 ? 22.802 -10.012 98.992 1.00 82.82 ? 186 GLU C N 1 ATOM 3706 C CA . GLU C 3 186 ? 22.329 -10.393 100.335 1.00 83.19 ? 186 GLU C CA 1 ATOM 3707 C C . GLU C 3 186 ? 21.657 -9.237 101.094 1.00 81.50 ? 186 GLU C C 1 ATOM 3708 O O . GLU C 3 186 ? 21.177 -9.431 102.211 1.00 77.51 ? 186 GLU C O 1 ATOM 3709 C CB . GLU C 3 186 ? 23.448 -11.042 101.164 1.00 83.53 ? 186 GLU C CB 1 ATOM 3710 C CG . GLU C 3 186 ? 22.957 -12.136 102.114 1.00 84.83 ? 186 GLU C CG 1 ATOM 3711 C CD . GLU C 3 186 ? 22.478 -13.395 101.398 1.00 85.59 ? 186 GLU C CD 1 ATOM 3712 O OE1 . GLU C 3 186 ? 23.320 -14.265 101.092 1.00 86.21 ? 186 GLU C OE1 1 ATOM 3713 O OE2 . GLU C 3 186 ? 21.256 -13.525 101.154 1.00 83.99 ? 186 GLU C OE2 1 ATOM 3714 N N . SER C 3 187 ? 21.606 -8.050 100.478 1.00 78.88 ? 187 SER C N 1 ATOM 3715 C CA . SER C 3 187 ? 20.628 -7.012 100.847 1.00 78.98 ? 187 SER C CA 1 ATOM 3716 C C . SER C 3 187 ? 19.172 -7.506 100.785 1.00 78.22 ? 187 SER C C 1 ATOM 3717 O O . SER C 3 187 ? 18.293 -6.887 101.381 1.00 78.69 ? 187 SER C O 1 ATOM 3718 C CB . SER C 3 187 ? 20.761 -5.772 99.945 1.00 79.17 ? 187 SER C CB 1 ATOM 3719 O OG . SER C 3 187 ? 21.832 -4.940 100.350 1.00 81.31 ? 187 SER C OG 1 ATOM 3720 N N . HIS C 3 188 ? 18.917 -8.578 100.030 1.00 76.29 ? 188 HIS C N 1 ATOM 3721 C CA . HIS C 3 188 ? 17.608 -9.225 99.977 1.00 75.32 ? 188 HIS C CA 1 ATOM 3722 C C . HIS C 3 188 ? 17.734 -10.717 100.292 1.00 75.88 ? 188 HIS C C 1 ATOM 3723 O O . HIS C 3 188 ? 18.842 -11.256 100.377 1.00 73.40 ? 188 HIS C O 1 ATOM 3724 C CB . HIS C 3 188 ? 16.986 -9.004 98.598 1.00 76.74 ? 188 HIS C CB 1 ATOM 3725 C CG . HIS C 3 188 ? 16.898 -7.560 98.208 1.00 77.14 ? 188 HIS C CG 1 ATOM 3726 N ND1 . HIS C 3 188 ? 17.877 -6.924 97.473 1.00 75.16 ? 188 HIS C ND1 1 ATOM 3727 C CD2 . HIS C 3 188 ? 15.959 -6.623 98.476 1.00 78.56 ? 188 HIS C CD2 1 ATOM 3728 C CE1 . HIS C 3 188 ? 17.536 -5.659 97.296 1.00 76.74 ? 188 HIS C CE1 1 ATOM 3729 N NE2 . HIS C 3 188 ? 16.376 -5.452 97.892 1.00 79.56 ? 188 HIS C NE2 1 ATOM 3730 N N . ASN C 3 189 ? 16.586 -11.370 100.460 1.00 78.06 ? 189 ASN C N 1 ATOM 3731 C CA . ASN C 3 189 ? 16.513 -12.734 100.980 1.00 82.59 ? 189 ASN C CA 1 ATOM 3732 C C . ASN C 3 189 ? 15.899 -13.721 99.983 1.00 86.80 ? 189 ASN C C 1 ATOM 3733 O O . ASN C 3 189 ? 16.541 -14.712 99.629 1.00 91.25 ? 189 ASN C O 1 ATOM 3734 C CB . ASN C 3 189 ? 15.716 -12.735 102.291 1.00 84.38 ? 189 ASN C CB 1 ATOM 3735 C CG . ASN C 3 189 ? 16.065 -13.910 103.189 1.00 84.56 ? 189 ASN C CG 1 ATOM 3736 O OD1 . ASN C 3 189 ? 15.796 -15.062 102.861 1.00 83.46 ? 189 ASN C OD1 1 ATOM 3737 N ND2 . ASN C 3 189 ? 16.660 -13.617 104.338 1.00 88.56 ? 189 ASN C ND2 1 ATOM 3738 N N . LEU C 3 190 ? 14.669 -13.448 99.538 1.00 87.94 ? 190 LEU C N 1 ATOM 3739 C CA . LEU C 3 190 ? 13.902 -14.365 98.675 1.00 85.97 ? 190 LEU C CA 1 ATOM 3740 C C . LEU C 3 190 ? 14.110 -14.080 97.180 1.00 82.93 ? 190 LEU C C 1 ATOM 3741 O O . LEU C 3 190 ? 13.692 -13.027 96.689 1.00 80.04 ? 190 LEU C O 1 ATOM 3742 C CB . LEU C 3 190 ? 12.413 -14.263 99.021 1.00 86.89 ? 190 LEU C CB 1 ATOM 3743 C CG . LEU C 3 190 ? 11.416 -15.167 98.293 1.00 87.82 ? 190 LEU C CG 1 ATOM 3744 C CD1 . LEU C 3 190 ? 11.730 -16.636 98.536 1.00 87.22 ? 190 LEU C CD1 1 ATOM 3745 C CD2 . LEU C 3 190 ? 10.000 -14.831 98.736 1.00 87.41 ? 190 LEU C CD2 1 ATOM 3746 N N . TYR C 3 191 ? 14.733 -15.030 96.471 1.00 79.84 ? 191 TYR C N 1 ATOM 3747 C CA . TYR C 3 191 ? 15.033 -14.909 95.030 1.00 76.57 ? 191 TYR C CA 1 ATOM 3748 C C . TYR C 3 191 ? 14.241 -15.918 94.197 1.00 73.28 ? 191 TYR C C 1 ATOM 3749 O O . TYR C 3 191 ? 14.428 -17.133 94.340 1.00 70.03 ? 191 TYR C O 1 ATOM 3750 C CB . TYR C 3 191 ? 16.533 -15.096 94.785 1.00 76.88 ? 191 TYR C CB 1 ATOM 3751 C CG . TYR C 3 191 ? 17.326 -13.852 95.084 1.00 77.80 ? 191 TYR C CG 1 ATOM 3752 C CD1 . TYR C 3 191 ? 17.256 -12.754 94.231 1.00 79.34 ? 191 TYR C CD1 1 ATOM 3753 C CD2 . TYR C 3 191 ? 18.127 -13.753 96.227 1.00 76.37 ? 191 TYR C CD2 1 ATOM 3754 C CE1 . TYR C 3 191 ? 17.964 -11.595 94.494 1.00 80.13 ? 191 TYR C CE1 1 ATOM 3755 C CE2 . TYR C 3 191 ? 18.842 -12.594 96.498 1.00 76.69 ? 191 TYR C CE2 1 ATOM 3756 C CZ . TYR C 3 191 ? 18.753 -11.519 95.624 1.00 79.17 ? 191 TYR C CZ 1 ATOM 3757 O OH . TYR C 3 191 ? 19.437 -10.354 95.849 1.00 82.04 ? 191 TYR C OH 1 ATOM 3758 N N . THR C 3 192 ? 13.388 -15.404 93.306 1.00 69.70 ? 192 THR C N 1 ATOM 3759 C CA . THR C 3 192 ? 12.395 -16.222 92.592 1.00 69.31 ? 192 THR C CA 1 ATOM 3760 C C . THR C 3 192 ? 12.362 -15.950 91.079 1.00 67.10 ? 192 THR C C 1 ATOM 3761 O O . THR C 3 192 ? 12.444 -14.800 90.645 1.00 65.33 ? 192 THR C O 1 ATOM 3762 C CB . THR C 3 192 ? 10.966 -16.091 93.207 1.00 68.32 ? 192 THR C CB 1 ATOM 3763 O OG1 . THR C 3 192 ? 10.008 -15.831 92.175 1.00 67.62 ? 192 THR C OG1 1 ATOM 3764 C CG2 . THR C 3 192 ? 10.877 -14.992 94.281 1.00 69.16 ? 192 THR C CG2 1 ATOM 3765 N N . CYS C 3 193 ? 12.237 -17.032 90.303 1.00 66.07 ? 193 CYS C N 1 ATOM 3766 C CA . CYS C 3 193 ? 12.144 -16.994 88.841 1.00 65.79 ? 193 CYS C CA 1 ATOM 3767 C C . CYS C 3 193 ? 10.748 -17.476 88.438 1.00 61.03 ? 193 CYS C C 1 ATOM 3768 O O . CYS C 3 193 ? 10.360 -18.596 88.765 1.00 56.80 ? 193 CYS C O 1 ATOM 3769 C CB . CYS C 3 193 ? 13.219 -17.897 88.215 1.00 69.27 ? 193 CYS C CB 1 ATOM 3770 S SG . CYS C 3 193 ? 13.264 -17.838 86.409 1.00 79.57 ? 193 CYS C SG 1 ATOM 3771 N N . GLU C 3 194 ? 10.008 -16.621 87.731 1.00 61.97 ? 194 GLU C N 1 ATOM 3772 C CA . GLU C 3 194 ? 8.595 -16.851 87.397 1.00 63.74 ? 194 GLU C CA 1 ATOM 3773 C C . GLU C 3 194 ? 8.405 -16.885 85.876 1.00 62.29 ? 194 GLU C C 1 ATOM 3774 O O . GLU C 3 194 ? 8.621 -15.877 85.200 1.00 60.88 ? 194 GLU C O 1 ATOM 3775 C CB . GLU C 3 194 ? 7.736 -15.750 88.024 1.00 65.97 ? 194 GLU C CB 1 ATOM 3776 C CG . GLU C 3 194 ? 6.253 -16.066 88.102 1.00 69.41 ? 194 GLU C CG 1 ATOM 3777 C CD . GLU C 3 194 ? 5.491 -15.086 88.985 1.00 73.86 ? 194 GLU C CD 1 ATOM 3778 O OE1 . GLU C 3 194 ? 5.067 -15.480 90.096 1.00 74.00 ? 194 GLU C OE1 1 ATOM 3779 O OE2 . GLU C 3 194 ? 5.323 -13.916 88.571 1.00 76.94 ? 194 GLU C OE2 1 ATOM 3780 N N . VAL C 3 195 ? 7.990 -18.047 85.361 1.00 60.99 ? 195 VAL C N 1 ATOM 3781 C CA . VAL C 3 195 ? 7.976 -18.345 83.925 1.00 60.17 ? 195 VAL C CA 1 ATOM 3782 C C . VAL C 3 195 ? 6.553 -18.559 83.427 1.00 58.65 ? 195 VAL C C 1 ATOM 3783 O O . VAL C 3 195 ? 5.860 -19.438 83.923 1.00 59.35 ? 195 VAL C O 1 ATOM 3784 C CB . VAL C 3 195 ? 8.773 -19.635 83.628 1.00 60.94 ? 195 VAL C CB 1 ATOM 3785 C CG1 . VAL C 3 195 ? 8.808 -19.923 82.126 1.00 61.38 ? 195 VAL C CG1 1 ATOM 3786 C CG2 . VAL C 3 195 ? 10.181 -19.537 84.207 1.00 60.87 ? 195 VAL C CG2 1 ATOM 3787 N N . VAL C 3 196 ? 6.148 -17.779 82.427 1.00 59.02 ? 196 VAL C N 1 ATOM 3788 C CA . VAL C 3 196 ? 4.789 -17.819 81.877 1.00 62.87 ? 196 VAL C CA 1 ATOM 3789 C C . VAL C 3 196 ? 4.830 -18.312 80.434 1.00 65.31 ? 196 VAL C C 1 ATOM 3790 O O . VAL C 3 196 ? 5.398 -17.654 79.563 1.00 67.34 ? 196 VAL C O 1 ATOM 3791 C CB . VAL C 3 196 ? 4.129 -16.421 81.898 1.00 63.77 ? 196 VAL C CB 1 ATOM 3792 C CG1 . VAL C 3 196 ? 2.750 -16.452 81.241 1.00 63.73 ? 196 VAL C CG1 1 ATOM 3793 C CG2 . VAL C 3 196 ? 4.022 -15.895 83.324 1.00 65.31 ? 196 VAL C CG2 1 ATOM 3794 N N . HIS C 3 197 ? 4.213 -19.464 80.195 1.00 66.70 ? 197 HIS C N 1 ATOM 3795 C CA . HIS C 3 197 ? 4.124 -20.054 78.867 1.00 68.91 ? 197 HIS C CA 1 ATOM 3796 C C . HIS C 3 197 ? 2.725 -20.618 78.699 1.00 71.59 ? 197 HIS C C 1 ATOM 3797 O O . HIS C 3 197 ? 2.097 -21.020 79.678 1.00 74.09 ? 197 HIS C O 1 ATOM 3798 C CB . HIS C 3 197 ? 5.174 -21.156 78.719 1.00 70.37 ? 197 HIS C CB 1 ATOM 3799 C CG . HIS C 3 197 ? 5.340 -21.656 77.319 1.00 72.51 ? 197 HIS C CG 1 ATOM 3800 N ND1 . HIS C 3 197 ? 5.413 -20.812 76.233 1.00 77.37 ? 197 HIS C ND1 1 ATOM 3801 C CD2 . HIS C 3 197 ? 5.473 -22.910 76.829 1.00 73.84 ? 197 HIS C CD2 1 ATOM 3802 C CE1 . HIS C 3 197 ? 5.566 -21.525 75.133 1.00 76.76 ? 197 HIS C CE1 1 ATOM 3803 N NE2 . HIS C 3 197 ? 5.610 -22.802 75.467 1.00 75.13 ? 197 HIS C NE2 1 ATOM 3804 N N . LYS C 3 198 ? 2.237 -20.649 77.463 1.00 75.33 ? 198 LYS C N 1 ATOM 3805 C CA . LYS C 3 198 ? 0.861 -21.089 77.196 1.00 78.84 ? 198 LYS C CA 1 ATOM 3806 C C . LYS C 3 198 ? 0.578 -22.584 77.472 1.00 77.27 ? 198 LYS C C 1 ATOM 3807 O O . LYS C 3 198 ? -0.580 -23.000 77.414 1.00 77.01 ? 198 LYS C O 1 ATOM 3808 C CB . LYS C 3 198 ? 0.427 -20.706 75.774 1.00 83.53 ? 198 LYS C CB 1 ATOM 3809 C CG . LYS C 3 198 ? 1.147 -21.440 74.646 1.00 89.18 ? 198 LYS C CG 1 ATOM 3810 C CD . LYS C 3 198 ? 0.404 -21.311 73.325 1.00 93.11 ? 198 LYS C CD 1 ATOM 3811 C CE . LYS C 3 198 ? -0.890 -22.113 73.317 1.00 95.89 ? 198 LYS C CE 1 ATOM 3812 N NZ . LYS C 3 198 ? -1.431 -22.299 71.942 1.00 99.24 ? 198 LYS C NZ 1 ATOM 3813 N N . THR C 3 199 ? 1.614 -23.377 77.775 1.00 75.32 ? 199 THR C N 1 ATOM 3814 C CA . THR C 3 199 ? 1.432 -24.755 78.267 1.00 77.95 ? 199 THR C CA 1 ATOM 3815 C C . THR C 3 199 ? 1.055 -24.860 79.763 1.00 80.34 ? 199 THR C C 1 ATOM 3816 O O . THR C 3 199 ? 1.045 -25.962 80.319 1.00 82.76 ? 199 THR C O 1 ATOM 3817 C CB . THR C 3 199 ? 2.689 -25.620 78.023 1.00 77.75 ? 199 THR C CB 1 ATOM 3818 O OG1 . THR C 3 199 ? 3.797 -25.077 78.750 1.00 75.85 ? 199 THR C OG1 1 ATOM 3819 C CG2 . THR C 3 199 ? 3.021 -25.695 76.536 1.00 78.86 ? 199 THR C CG2 1 ATOM 3820 N N . SER C 3 200 ? 0.784 -23.729 80.419 1.00 79.16 ? 200 SER C N 1 ATOM 3821 C CA . SER C 3 200 ? 0.121 -23.725 81.725 1.00 76.02 ? 200 SER C CA 1 ATOM 3822 C C . SER C 3 200 ? -0.713 -22.458 81.885 1.00 73.75 ? 200 SER C C 1 ATOM 3823 O O . SER C 3 200 ? -0.380 -21.413 81.320 1.00 67.29 ? 200 SER C O 1 ATOM 3824 C CB . SER C 3 200 ? 1.148 -23.829 82.854 1.00 75.42 ? 200 SER C CB 1 ATOM 3825 O OG . SER C 3 200 ? 0.506 -23.894 84.118 1.00 73.97 ? 200 SER C OG 1 ATOM 3826 N N . SER C 3 201 ? -1.803 -22.565 82.644 1.00 75.97 ? 201 SER C N 1 ATOM 3827 C CA . SER C 3 201 ? -2.655 -21.411 82.948 1.00 79.39 ? 201 SER C CA 1 ATOM 3828 C C . SER C 3 201 ? -1.915 -20.488 83.909 1.00 79.42 ? 201 SER C C 1 ATOM 3829 O O . SER C 3 201 ? -1.698 -19.310 83.620 1.00 80.56 ? 201 SER C O 1 ATOM 3830 C CB . SER C 3 201 ? -3.987 -21.861 83.561 1.00 80.47 ? 201 SER C CB 1 ATOM 3831 O OG . SER C 3 201 ? -3.792 -22.552 84.786 1.00 80.69 ? 201 SER C OG 1 ATOM 3832 N N . SER C 3 202 ? -1.520 -21.055 85.045 1.00 77.68 ? 202 SER C N 1 ATOM 3833 C CA . SER C 3 202 ? -0.686 -20.366 86.021 1.00 76.68 ? 202 SER C CA 1 ATOM 3834 C C . SER C 3 202 ? 0.781 -20.457 85.590 1.00 72.10 ? 202 SER C C 1 ATOM 3835 O O . SER C 3 202 ? 1.141 -21.363 84.840 1.00 72.57 ? 202 SER C O 1 ATOM 3836 C CB . SER C 3 202 ? -0.866 -21.001 87.403 1.00 77.32 ? 202 SER C CB 1 ATOM 3837 O OG . SER C 3 202 ? -0.691 -22.408 87.337 1.00 79.19 ? 202 SER C OG 1 ATOM 3838 N N . PRO C 3 203 ? 1.633 -19.522 86.059 1.00 67.40 ? 203 PRO C N 1 ATOM 3839 C CA . PRO C 3 203 ? 3.066 -19.625 85.775 1.00 64.81 ? 203 PRO C CA 1 ATOM 3840 C C . PRO C 3 203 ? 3.757 -20.777 86.502 1.00 63.41 ? 203 PRO C C 1 ATOM 3841 O O . PRO C 3 203 ? 3.281 -21.242 87.536 1.00 67.85 ? 203 PRO C O 1 ATOM 3842 C CB . PRO C 3 203 ? 3.624 -18.287 86.275 1.00 64.15 ? 203 PRO C CB 1 ATOM 3843 C CG . PRO C 3 203 ? 2.641 -17.810 87.278 1.00 63.99 ? 203 PRO C CG 1 ATOM 3844 C CD . PRO C 3 203 ? 1.309 -18.276 86.779 1.00 66.02 ? 203 PRO C CD 1 ATOM 3845 N N . VAL C 3 204 ? 4.867 -21.232 85.937 1.00 60.68 ? 204 VAL C N 1 ATOM 3846 C CA . VAL C 3 204 ? 5.782 -22.127 86.627 1.00 60.03 ? 204 VAL C CA 1 ATOM 3847 C C . VAL C 3 204 ? 6.651 -21.232 87.503 1.00 60.32 ? 204 VAL C C 1 ATOM 3848 O O . VAL C 3 204 ? 7.073 -20.165 87.059 1.00 60.00 ? 204 VAL C O 1 ATOM 3849 C CB . VAL C 3 204 ? 6.664 -22.915 85.631 1.00 58.37 ? 204 VAL C CB 1 ATOM 3850 C CG1 . VAL C 3 204 ? 7.707 -23.762 86.360 1.00 56.83 ? 204 VAL C CG1 1 ATOM 3851 C CG2 . VAL C 3 204 ? 5.793 -23.775 84.729 1.00 58.16 ? 204 VAL C CG2 1 ATOM 3852 N N . VAL C 3 205 ? 6.913 -21.667 88.735 1.00 62.74 ? 205 VAL C N 1 ATOM 3853 C CA . VAL C 3 205 ? 7.755 -20.912 89.677 1.00 63.07 ? 205 VAL C CA 1 ATOM 3854 C C . VAL C 3 205 ? 8.878 -21.787 90.202 1.00 61.87 ? 205 VAL C C 1 ATOM 3855 O O . VAL C 3 205 ? 8.656 -22.942 90.558 1.00 64.12 ? 205 VAL C O 1 ATOM 3856 C CB . VAL C 3 205 ? 6.962 -20.324 90.874 1.00 63.42 ? 205 VAL C CB 1 ATOM 3857 C CG1 . VAL C 3 205 ? 6.145 -19.117 90.431 1.00 62.48 ? 205 VAL C CG1 1 ATOM 3858 C CG2 . VAL C 3 205 ? 6.064 -21.367 91.538 1.00 66.47 ? 205 VAL C CG2 1 ATOM 3859 N N . LYS C 3 206 ? 10.087 -21.235 90.206 1.00 62.74 ? 206 LYS C N 1 ATOM 3860 C CA . LYS C 3 206 ? 11.244 -21.844 90.863 1.00 63.43 ? 206 LYS C CA 1 ATOM 3861 C C . LYS C 3 206 ? 11.961 -20.749 91.639 1.00 63.15 ? 206 LYS C C 1 ATOM 3862 O O . LYS C 3 206 ? 11.996 -19.594 91.202 1.00 58.49 ? 206 LYS C O 1 ATOM 3863 C CB . LYS C 3 206 ? 12.187 -22.489 89.844 1.00 63.48 ? 206 LYS C CB 1 ATOM 3864 C CG . LYS C 3 206 ? 11.602 -23.694 89.116 1.00 64.39 ? 206 LYS C CG 1 ATOM 3865 C CD . LYS C 3 206 ? 11.499 -24.925 90.004 1.00 65.53 ? 206 LYS C CD 1 ATOM 3866 C CE . LYS C 3 206 ? 10.693 -26.023 89.327 1.00 67.15 ? 206 LYS C CE 1 ATOM 3867 N NZ . LYS C 3 206 ? 10.610 -27.255 90.158 1.00 69.09 ? 206 LYS C NZ 1 ATOM 3868 N N . SER C 3 207 ? 12.519 -21.110 92.794 1.00 66.29 ? 207 SER C N 1 ATOM 3869 C CA . SER C 3 207 ? 13.082 -20.120 93.719 1.00 65.94 ? 207 SER C CA 1 ATOM 3870 C C . SER C 3 207 ? 14.008 -20.715 94.783 1.00 68.39 ? 207 SER C C 1 ATOM 3871 O O . SER C 3 207 ? 14.158 -21.937 94.899 1.00 63.77 ? 207 SER C O 1 ATOM 3872 C CB . SER C 3 207 ? 11.938 -19.333 94.380 1.00 61.31 ? 207 SER C CB 1 ATOM 3873 O OG . SER C 3 207 ? 10.931 -20.191 94.873 1.00 56.93 ? 207 SER C OG 1 ATOM 3874 N N . PHE C 3 208 ? 14.644 -19.810 95.526 1.00 75.83 ? 208 PHE C N 1 ATOM 3875 C CA . PHE C 3 208 ? 15.469 -20.135 96.692 1.00 79.31 ? 208 PHE C CA 1 ATOM 3876 C C . PHE C 3 208 ? 15.540 -18.916 97.633 1.00 81.90 ? 208 PHE C C 1 ATOM 3877 O O . PHE C 3 208 ? 14.931 -17.869 97.368 1.00 79.61 ? 208 PHE C O 1 ATOM 3878 C CB . PHE C 3 208 ? 16.880 -20.534 96.236 1.00 81.62 ? 208 PHE C CB 1 ATOM 3879 C CG . PHE C 3 208 ? 17.642 -19.413 95.575 1.00 84.21 ? 208 PHE C CG 1 ATOM 3880 C CD1 . PHE C 3 208 ? 18.445 -18.555 96.327 1.00 84.57 ? 208 PHE C CD1 1 ATOM 3881 C CD2 . PHE C 3 208 ? 17.539 -19.199 94.203 1.00 84.98 ? 208 PHE C CD2 1 ATOM 3882 C CE1 . PHE C 3 208 ? 19.134 -17.514 95.722 1.00 86.13 ? 208 PHE C CE1 1 ATOM 3883 C CE2 . PHE C 3 208 ? 18.229 -18.161 93.592 1.00 84.39 ? 208 PHE C CE2 1 ATOM 3884 C CZ . PHE C 3 208 ? 19.028 -17.319 94.351 1.00 85.95 ? 208 PHE C CZ 1 ATOM 3885 N N . ASN C 3 209 ? 16.291 -19.066 98.724 1.00 85.75 ? 209 ASN C N 1 ATOM 3886 C CA . ASN C 3 209 ? 16.668 -17.939 99.591 1.00 85.66 ? 209 ASN C CA 1 ATOM 3887 C C . ASN C 3 209 ? 17.944 -18.265 100.396 1.00 90.12 ? 209 ASN C C 1 ATOM 3888 O O . ASN C 3 209 ? 18.592 -19.284 100.130 1.00 87.37 ? 209 ASN C O 1 ATOM 3889 C CB . ASN C 3 209 ? 15.483 -17.543 100.488 1.00 82.76 ? 209 ASN C CB 1 ATOM 3890 C CG . ASN C 3 209 ? 14.989 -18.677 101.361 1.00 79.11 ? 209 ASN C CG 1 ATOM 3891 O OD1 . ASN C 3 209 ? 15.412 -19.820 101.222 1.00 78.41 ? 209 ASN C OD1 1 ATOM 3892 N ND2 . ASN C 3 209 ? 14.074 -18.360 102.267 1.00 78.07 ? 209 ASN C ND2 1 ATOM 3893 N N . ARG C 3 210 ? 18.309 -17.402 101.350 1.00 98.41 ? 210 ARG C N 1 ATOM 3894 C CA . ARG C 3 210 ? 19.515 -17.580 102.197 1.00 105.16 ? 210 ARG C CA 1 ATOM 3895 C C . ARG C 3 210 ? 19.778 -19.000 102.737 1.00 111.29 ? 210 ARG C C 1 ATOM 3896 O O . ARG C 3 210 ? 20.933 -19.436 102.774 1.00 114.55 ? 210 ARG C O 1 ATOM 3897 C CB . ARG C 3 210 ? 19.518 -16.573 103.364 1.00 105.12 ? 210 ARG C CB 1 ATOM 3898 C CG . ARG C 3 210 ? 18.361 -16.701 104.350 1.00 104.05 ? 210 ARG C CG 1 ATOM 3899 C CD . ARG C 3 210 ? 18.728 -17.476 105.606 1.00 103.17 ? 210 ARG C CD 1 ATOM 3900 N NE . ARG C 3 210 ? 17.539 -17.924 106.324 1.00 104.10 ? 210 ARG C NE 1 ATOM 3901 N N . ASN C 3 211 ? 18.725 -19.711 103.151 1.00 114.88 ? 211 ASN C N 1 ATOM 3902 C CA . ASN C 3 211 ? 18.855 -21.103 103.611 1.00 112.94 ? 211 ASN C CA 1 ATOM 3903 C C . ASN C 3 211 ? 19.118 -22.034 102.427 1.00 111.20 ? 211 ASN C C 1 ATOM 3904 O O . ASN C 3 211 ? 20.123 -22.742 102.394 1.00 113.45 ? 211 ASN C O 1 ATOM 3905 C CB . ASN C 3 211 ? 17.597 -21.557 104.365 1.00 112.84 ? 211 ASN C CB 1 ATOM 3906 C CG . ASN C 3 211 ? 17.670 -23.012 104.815 1.00 113.60 ? 211 ASN C CG 1 ATOM 3907 O OD1 . ASN C 3 211 ? 16.751 -23.794 104.575 1.00 112.78 ? 211 ASN C OD1 1 ATOM 3908 N ND2 . ASN C 3 211 ? 18.770 -23.380 105.462 1.00 113.91 ? 211 ASN C ND2 1 ATOM 3909 N N . GLU D 4 1 ? 36.532 -36.475 53.066 1.00 85.00 ? 1 GLU D N 1 ATOM 3910 C CA . GLU D 4 1 ? 37.743 -36.338 52.208 1.00 86.20 ? 1 GLU D CA 1 ATOM 3911 C C . GLU D 4 1 ? 37.979 -34.876 51.822 1.00 84.88 ? 1 GLU D C 1 ATOM 3912 O O . GLU D 4 1 ? 38.990 -34.293 52.212 1.00 86.74 ? 1 GLU D O 1 ATOM 3913 C CB . GLU D 4 1 ? 37.633 -37.229 50.964 1.00 88.40 ? 1 GLU D CB 1 ATOM 3914 C CG . GLU D 4 1 ? 37.458 -38.710 51.289 1.00 91.25 ? 1 GLU D CG 1 ATOM 3915 C CD . GLU D 4 1 ? 37.689 -39.630 50.097 1.00 92.79 ? 1 GLU D CD 1 ATOM 3916 O OE1 . GLU D 4 1 ? 37.266 -39.283 48.973 1.00 96.42 ? 1 GLU D OE1 1 ATOM 3917 O OE2 . GLU D 4 1 ? 38.288 -40.712 50.286 1.00 90.03 ? 1 GLU D OE2 1 ATOM 3918 N N . VAL D 4 2 ? 37.038 -34.284 51.085 1.00 81.72 ? 2 VAL D N 1 ATOM 3919 C CA . VAL D 4 2 ? 37.149 -32.883 50.659 1.00 82.86 ? 2 VAL D CA 1 ATOM 3920 C C . VAL D 4 2 ? 36.873 -31.965 51.854 1.00 84.20 ? 2 VAL D C 1 ATOM 3921 O O . VAL D 4 2 ? 35.720 -31.822 52.261 1.00 81.82 ? 2 VAL D O 1 ATOM 3922 C CB . VAL D 4 2 ? 36.176 -32.555 49.496 1.00 81.29 ? 2 VAL D CB 1 ATOM 3923 C CG1 . VAL D 4 2 ? 36.191 -31.064 49.157 1.00 79.65 ? 2 VAL D CG1 1 ATOM 3924 C CG2 . VAL D 4 2 ? 36.527 -33.378 48.265 1.00 81.96 ? 2 VAL D CG2 1 ATOM 3925 N N . GLN D 4 3 ? 37.929 -31.347 52.394 1.00 87.83 ? 3 GLN D N 1 ATOM 3926 C CA . GLN D 4 3 ? 37.831 -30.485 53.584 1.00 91.06 ? 3 GLN D CA 1 ATOM 3927 C C . GLN D 4 3 ? 38.547 -29.143 53.430 1.00 89.69 ? 3 GLN D C 1 ATOM 3928 O O . GLN D 4 3 ? 39.573 -29.048 52.750 1.00 87.51 ? 3 GLN D O 1 ATOM 3929 C CB . GLN D 4 3 ? 38.414 -31.198 54.804 1.00 95.70 ? 3 GLN D CB 1 ATOM 3930 C CG . GLN D 4 3 ? 37.618 -32.406 55.263 1.00 99.97 ? 3 GLN D CG 1 ATOM 3931 C CD . GLN D 4 3 ? 38.028 -32.881 56.644 1.00 102.74 ? 3 GLN D CD 1 ATOM 3932 O OE1 . GLN D 4 3 ? 39.216 -32.952 56.965 1.00 104.20 ? 3 GLN D OE1 1 ATOM 3933 N NE2 . GLN D 4 3 ? 37.041 -33.211 57.471 1.00 105.48 ? 3 GLN D NE2 1 ATOM 3934 N N . LEU D 4 4 ? 37.990 -28.124 54.087 1.00 91.84 ? 4 LEU D N 1 ATOM 3935 C CA . LEU D 4 4 ? 38.604 -26.799 54.218 1.00 93.54 ? 4 LEU D CA 1 ATOM 3936 C C . LEU D 4 4 ? 38.452 -26.313 55.663 1.00 94.03 ? 4 LEU D C 1 ATOM 3937 O O . LEU D 4 4 ? 37.380 -26.462 56.256 1.00 89.77 ? 4 LEU D O 1 ATOM 3938 C CB . LEU D 4 4 ? 37.940 -25.785 53.277 1.00 94.20 ? 4 LEU D CB 1 ATOM 3939 C CG . LEU D 4 4 ? 37.889 -26.106 51.776 1.00 97.14 ? 4 LEU D CG 1 ATOM 3940 C CD1 . LEU D 4 4 ? 36.595 -26.819 51.397 1.00 98.11 ? 4 LEU D CD1 1 ATOM 3941 C CD2 . LEU D 4 4 ? 38.039 -24.845 50.938 1.00 96.15 ? 4 LEU D CD2 1 ATOM 3942 N N . GLN D 4 5 ? 39.522 -25.744 56.223 1.00 94.04 ? 5 GLN D N 1 ATOM 3943 C CA . GLN D 4 5 ? 39.484 -25.125 57.552 1.00 92.20 ? 5 GLN D CA 1 ATOM 3944 C C . GLN D 4 5 ? 40.068 -23.714 57.482 1.00 89.83 ? 5 GLN D C 1 ATOM 3945 O O . GLN D 4 5 ? 41.185 -23.532 57.003 1.00 89.34 ? 5 GLN D O 1 ATOM 3946 C CB . GLN D 4 5 ? 40.263 -25.960 58.576 1.00 93.33 ? 5 GLN D CB 1 ATOM 3947 C CG . GLN D 4 5 ? 39.741 -27.382 58.786 1.00 93.59 ? 5 GLN D CG 1 ATOM 3948 C CD . GLN D 4 5 ? 40.263 -28.396 57.773 1.00 93.09 ? 5 GLN D CD 1 ATOM 3949 O OE1 . GLN D 4 5 ? 41.042 -28.064 56.878 1.00 90.62 ? 5 GLN D OE1 1 ATOM 3950 N NE2 . GLN D 4 5 ? 39.829 -29.647 57.914 1.00 90.74 ? 5 GLN D NE2 1 ATOM 3951 N N . GLU D 4 6 ? 39.308 -22.733 57.967 1.00 90.42 ? 6 GLU D N 1 ATOM 3952 C CA . GLU D 4 6 ? 39.739 -21.336 58.016 1.00 93.16 ? 6 GLU D CA 1 ATOM 3953 C C . GLU D 4 6 ? 40.225 -21.002 59.421 1.00 94.73 ? 6 GLU D C 1 ATOM 3954 O O . GLU D 4 6 ? 39.454 -21.094 60.378 1.00 93.94 ? 6 GLU D O 1 ATOM 3955 C CB . GLU D 4 6 ? 38.587 -20.395 57.657 1.00 96.66 ? 6 GLU D CB 1 ATOM 3956 C CG . GLU D 4 6 ? 37.968 -20.641 56.290 1.00 99.51 ? 6 GLU D CG 1 ATOM 3957 C CD . GLU D 4 6 ? 36.832 -21.653 56.302 1.00 102.18 ? 6 GLU D CD 1 ATOM 3958 O OE1 . GLU D 4 6 ? 36.799 -22.523 57.199 1.00 103.59 ? 6 GLU D OE1 1 ATOM 3959 O OE2 . GLU D 4 6 ? 35.969 -21.585 55.401 1.00 104.80 ? 6 GLU D OE2 1 ATOM 3960 N N . SER D 4 7 ? 41.495 -20.618 59.539 1.00 98.20 ? 7 SER D N 1 ATOM 3961 C CA . SER D 4 7 ? 42.090 -20.203 60.815 1.00 97.54 ? 7 SER D CA 1 ATOM 3962 C C . SER D 4 7 ? 42.547 -18.746 60.739 1.00 99.49 ? 7 SER D C 1 ATOM 3963 O O . SER D 4 7 ? 42.830 -18.232 59.654 1.00 97.52 ? 7 SER D O 1 ATOM 3964 C CB . SER D 4 7 ? 43.267 -21.114 61.179 1.00 95.58 ? 7 SER D CB 1 ATOM 3965 O OG . SER D 4 7 ? 44.217 -21.174 60.131 1.00 90.83 ? 7 SER D OG 1 ATOM 3966 N N . GLY D 4 8 ? 42.606 -18.092 61.899 1.00 103.43 ? 8 GLY D N 1 ATOM 3967 C CA . GLY D 4 8 ? 43.040 -16.694 61.998 1.00 106.72 ? 8 GLY D CA 1 ATOM 3968 C C . GLY D 4 8 ? 42.461 -15.981 63.210 1.00 108.83 ? 8 GLY D C 1 ATOM 3969 O O . GLY D 4 8 ? 41.407 -16.379 63.711 1.00 112.17 ? 8 GLY D O 1 ATOM 3970 N N . PRO D 4 9 ? 43.129 -14.903 63.672 1.00 112.56 ? 9 PRO D N 1 ATOM 3971 C CA . PRO D 4 9 ? 42.750 -14.231 64.918 1.00 114.60 ? 9 PRO D CA 1 ATOM 3972 C C . PRO D 4 9 ? 41.405 -13.515 64.810 1.00 115.53 ? 9 PRO D C 1 ATOM 3973 O O . PRO D 4 9 ? 41.157 -12.822 63.820 1.00 121.89 ? 9 PRO D O 1 ATOM 3974 C CB . PRO D 4 9 ? 43.882 -13.220 65.124 1.00 115.54 ? 9 PRO D CB 1 ATOM 3975 C CG . PRO D 4 9 ? 44.334 -12.890 63.746 1.00 113.48 ? 9 PRO D CG 1 ATOM 3976 C CD . PRO D 4 9 ? 44.168 -14.150 62.941 1.00 113.25 ? 9 PRO D CD 1 ATOM 3977 N N . GLY D 4 10 ? 40.551 -13.692 65.817 1.00 110.86 ? 10 GLY D N 1 ATOM 3978 C CA . GLY D 4 10 ? 39.223 -13.074 65.833 1.00 109.87 ? 10 GLY D CA 1 ATOM 3979 C C . GLY D 4 10 ? 39.269 -11.562 65.944 1.00 108.98 ? 10 GLY D C 1 ATOM 3980 O O . GLY D 4 10 ? 38.462 -10.861 65.325 1.00 96.52 ? 10 GLY D O 1 ATOM 3981 N N . LEU D 4 11 ? 40.218 -11.071 66.741 1.00 116.79 ? 11 LEU D N 1 ATOM 3982 C CA . LEU D 4 11 ? 40.454 -9.642 66.916 1.00 119.85 ? 11 LEU D CA 1 ATOM 3983 C C . LEU D 4 11 ? 41.644 -9.187 66.078 1.00 119.71 ? 11 LEU D C 1 ATOM 3984 O O . LEU D 4 11 ? 42.709 -9.814 66.098 1.00 117.47 ? 11 LEU D O 1 ATOM 3985 C CB . LEU D 4 11 ? 40.735 -9.319 68.388 1.00 120.57 ? 11 LEU D CB 1 ATOM 3986 C CG . LEU D 4 11 ? 40.803 -7.821 68.731 1.00 124.23 ? 11 LEU D CG 1 ATOM 3987 C CD1 . LEU D 4 11 ? 39.408 -7.212 68.774 1.00 123.87 ? 11 LEU D CD1 1 ATOM 3988 C CD2 . LEU D 4 11 ? 41.539 -7.571 70.039 1.00 126.89 ? 11 LEU D CD2 1 ATOM 3989 N N . VAL D 4 12 ? 41.437 -8.103 65.333 1.00 118.35 ? 12 VAL D N 1 ATOM 3990 C CA . VAL D 4 12 ? 42.521 -7.284 64.795 1.00 120.53 ? 12 VAL D CA 1 ATOM 3991 C C . VAL D 4 12 ? 42.105 -5.838 65.020 1.00 120.19 ? 12 VAL D C 1 ATOM 3992 O O . VAL D 4 12 ? 40.968 -5.473 64.717 1.00 121.07 ? 12 VAL D O 1 ATOM 3993 C CB . VAL D 4 12 ? 42.757 -7.522 63.289 1.00 121.92 ? 12 VAL D CB 1 ATOM 3994 C CG1 . VAL D 4 12 ? 43.888 -6.632 62.776 1.00 122.38 ? 12 VAL D CG1 1 ATOM 3995 C CG2 . VAL D 4 12 ? 43.058 -8.992 63.019 1.00 122.86 ? 12 VAL D CG2 1 ATOM 3996 N N . GLN D 4 13 ? 43.014 -5.025 65.553 1.00 117.95 ? 13 GLN D N 1 ATOM 3997 C CA . GLN D 4 13 ? 42.717 -3.620 65.847 1.00 116.76 ? 13 GLN D CA 1 ATOM 3998 C C . GLN D 4 13 ? 42.872 -2.783 64.566 1.00 109.36 ? 13 GLN D C 1 ATOM 3999 O O . GLN D 4 13 ? 43.716 -3.113 63.728 1.00 107.68 ? 13 GLN D O 1 ATOM 4000 C CB . GLN D 4 13 ? 43.616 -3.112 66.978 1.00 122.52 ? 13 GLN D CB 1 ATOM 4001 C CG . GLN D 4 13 ? 43.415 -3.883 68.282 1.00 126.28 ? 13 GLN D CG 1 ATOM 4002 C CD . GLN D 4 13 ? 44.348 -3.460 69.401 1.00 130.65 ? 13 GLN D CD 1 ATOM 4003 O OE1 . GLN D 4 13 ? 45.277 -2.677 69.200 1.00 134.66 ? 13 GLN D OE1 1 ATOM 4004 N NE2 . GLN D 4 13 ? 44.104 -3.991 70.596 1.00 129.43 ? 13 GLN D NE2 1 ATOM 4005 N N . PRO D 4 14 ? 42.065 -1.703 64.405 1.00 103.75 ? 14 PRO D N 1 ATOM 4006 C CA . PRO D 4 14 ? 41.969 -1.005 63.102 1.00 105.40 ? 14 PRO D CA 1 ATOM 4007 C C . PRO D 4 14 ? 43.276 -0.404 62.555 1.00 111.66 ? 14 PRO D C 1 ATOM 4008 O O . PRO D 4 14 ? 44.237 -0.210 63.305 1.00 115.63 ? 14 PRO D O 1 ATOM 4009 C CB . PRO D 4 14 ? 40.937 0.107 63.364 1.00 101.60 ? 14 PRO D CB 1 ATOM 4010 C CG . PRO D 4 14 ? 40.229 -0.290 64.612 1.00 100.88 ? 14 PRO D CG 1 ATOM 4011 C CD . PRO D 4 14 ? 41.240 -1.033 65.427 1.00 100.66 ? 14 PRO D CD 1 ATOM 4012 N N . SER D 4 15 ? 43.277 -0.109 61.253 1.00 114.82 ? 15 SER D N 1 ATOM 4013 C CA . SER D 4 15 ? 44.448 0.409 60.521 1.00 112.81 ? 15 SER D CA 1 ATOM 4014 C C . SER D 4 15 ? 45.644 -0.555 60.559 1.00 112.44 ? 15 SER D C 1 ATOM 4015 O O . SER D 4 15 ? 46.797 -0.129 60.681 1.00 114.10 ? 15 SER D O 1 ATOM 4016 C CB . SER D 4 15 ? 44.851 1.804 61.029 1.00 111.62 ? 15 SER D CB 1 ATOM 4017 O OG . SER D 4 15 ? 43.742 2.686 61.047 1.00 109.95 ? 15 SER D OG 1 ATOM 4018 N N . GLU D 4 16 ? 45.352 -1.852 60.452 1.00 110.15 ? 16 GLU D N 1 ATOM 4019 C CA . GLU D 4 16 ? 46.369 -2.908 60.452 1.00 110.50 ? 16 GLU D CA 1 ATOM 4020 C C . GLU D 4 16 ? 46.040 -3.941 59.365 1.00 105.60 ? 16 GLU D C 1 ATOM 4021 O O . GLU D 4 16 ? 45.090 -3.752 58.601 1.00 99.82 ? 16 GLU D O 1 ATOM 4022 C CB . GLU D 4 16 ? 46.446 -3.561 61.839 1.00 112.56 ? 16 GLU D CB 1 ATOM 4023 C CG . GLU D 4 16 ? 46.818 -2.596 62.957 1.00 115.16 ? 16 GLU D CG 1 ATOM 4024 C CD . GLU D 4 16 ? 47.002 -3.271 64.306 1.00 119.08 ? 16 GLU D CD 1 ATOM 4025 O OE1 . GLU D 4 16 ? 47.784 -2.742 65.127 1.00 116.24 ? 16 GLU D OE1 1 ATOM 4026 O OE2 . GLU D 4 16 ? 46.368 -4.322 64.553 1.00 123.97 ? 16 GLU D OE2 1 ATOM 4027 N N . THR D 4 17 ? 46.841 -5.007 59.284 1.00 102.72 ? 17 THR D N 1 ATOM 4028 C CA . THR D 4 17 ? 46.630 -6.092 58.318 1.00 100.91 ? 17 THR D CA 1 ATOM 4029 C C . THR D 4 17 ? 46.020 -7.335 58.970 1.00 98.88 ? 17 THR D C 1 ATOM 4030 O O . THR D 4 17 ? 46.309 -7.638 60.127 1.00 100.97 ? 17 THR D O 1 ATOM 4031 C CB . THR D 4 17 ? 47.952 -6.498 57.625 1.00 100.82 ? 17 THR D CB 1 ATOM 4032 O OG1 . THR D 4 17 ? 48.811 -7.160 58.562 1.00 99.13 ? 17 THR D OG1 1 ATOM 4033 C CG2 . THR D 4 17 ? 48.673 -5.276 57.044 1.00 101.05 ? 17 THR D CG2 1 ATOM 4034 N N . LEU D 4 18 ? 45.187 -8.043 58.204 1.00 94.28 ? 18 LEU D N 1 ATOM 4035 C CA . LEU D 4 18 ? 44.566 -9.301 58.622 1.00 88.93 ? 18 LEU D CA 1 ATOM 4036 C C . LEU D 4 18 ? 45.190 -10.417 57.810 1.00 83.95 ? 18 LEU D C 1 ATOM 4037 O O . LEU D 4 18 ? 45.175 -10.358 56.585 1.00 85.93 ? 18 LEU D O 1 ATOM 4038 C CB . LEU D 4 18 ? 43.051 -9.262 58.375 1.00 91.97 ? 18 LEU D CB 1 ATOM 4039 C CG . LEU D 4 18 ? 42.254 -10.572 58.232 1.00 92.64 ? 18 LEU D CG 1 ATOM 4040 C CD1 . LEU D 4 18 ? 42.385 -11.453 59.467 1.00 92.22 ? 18 LEU D CD1 1 ATOM 4041 C CD2 . LEU D 4 18 ? 40.796 -10.246 57.931 1.00 92.44 ? 18 LEU D CD2 1 ATOM 4042 N N . SER D 4 19 ? 45.719 -11.427 58.496 1.00 79.49 ? 19 SER D N 1 ATOM 4043 C CA . SER D 4 19 ? 46.332 -12.585 57.862 1.00 76.59 ? 19 SER D CA 1 ATOM 4044 C C . SER D 4 19 ? 45.531 -13.852 58.192 1.00 78.11 ? 19 SER D C 1 ATOM 4045 O O . SER D 4 19 ? 45.476 -14.271 59.352 1.00 77.15 ? 19 SER D O 1 ATOM 4046 C CB . SER D 4 19 ? 47.778 -12.726 58.333 1.00 75.75 ? 19 SER D CB 1 ATOM 4047 O OG . SER D 4 19 ? 48.434 -13.792 57.673 1.00 77.01 ? 19 SER D OG 1 ATOM 4048 N N . LEU D 4 20 ? 44.905 -14.440 57.166 1.00 79.82 ? 20 LEU D N 1 ATOM 4049 C CA . LEU D 4 20 ? 44.161 -15.704 57.282 1.00 75.78 ? 20 LEU D CA 1 ATOM 4050 C C . LEU D 4 20 ? 44.852 -16.837 56.536 1.00 72.61 ? 20 LEU D C 1 ATOM 4051 O O . LEU D 4 20 ? 45.723 -16.609 55.703 1.00 72.58 ? 20 LEU D O 1 ATOM 4052 C CB . LEU D 4 20 ? 42.746 -15.545 56.728 1.00 75.74 ? 20 LEU D CB 1 ATOM 4053 C CG . LEU D 4 20 ? 41.850 -14.515 57.409 1.00 77.93 ? 20 LEU D CG 1 ATOM 4054 C CD1 . LEU D 4 20 ? 40.518 -14.417 56.677 1.00 77.27 ? 20 LEU D CD1 1 ATOM 4055 C CD2 . LEU D 4 20 ? 41.640 -14.872 58.874 1.00 79.86 ? 20 LEU D CD2 1 ATOM 4056 N N . THR D 4 21 ? 44.438 -18.060 56.851 1.00 72.67 ? 21 THR D N 1 ATOM 4057 C CA . THR D 4 21 ? 44.961 -19.272 56.227 1.00 75.86 ? 21 THR D CA 1 ATOM 4058 C C . THR D 4 21 ? 43.802 -20.220 55.910 1.00 79.92 ? 21 THR D C 1 ATOM 4059 O O . THR D 4 21 ? 42.788 -20.215 56.611 1.00 85.10 ? 21 THR D O 1 ATOM 4060 C CB . THR D 4 21 ? 45.951 -19.990 57.164 1.00 75.11 ? 21 THR D CB 1 ATOM 4061 O OG1 . THR D 4 21 ? 46.845 -19.034 57.750 1.00 76.85 ? 21 THR D OG1 1 ATOM 4062 C CG2 . THR D 4 21 ? 46.754 -21.046 56.411 1.00 75.03 ? 21 THR D CG2 1 ATOM 4063 N N . CYS D 4 22 ? 43.951 -21.014 54.851 1.00 80.31 ? 22 CYS D N 1 ATOM 4064 C CA . CYS D 4 22 ? 42.966 -22.036 54.483 1.00 79.55 ? 22 CYS D CA 1 ATOM 4065 C C . CYS D 4 22 ? 43.692 -23.357 54.265 1.00 75.59 ? 22 CYS D C 1 ATOM 4066 O O . CYS D 4 22 ? 44.200 -23.635 53.179 1.00 73.03 ? 22 CYS D O 1 ATOM 4067 C CB . CYS D 4 22 ? 42.172 -21.615 53.236 1.00 82.75 ? 22 CYS D CB 1 ATOM 4068 S SG . CYS D 4 22 ? 41.018 -22.852 52.570 1.00 85.56 ? 22 CYS D SG 1 ATOM 4069 N N . THR D 4 23 ? 43.765 -24.153 55.327 1.00 75.20 ? 23 THR D N 1 ATOM 4070 C CA . THR D 4 23 ? 44.321 -25.502 55.252 1.00 74.74 ? 23 THR D CA 1 ATOM 4071 C C . THR D 4 23 ? 43.289 -26.406 54.582 1.00 75.48 ? 23 THR D C 1 ATOM 4072 O O . THR D 4 23 ? 42.084 -26.288 54.842 1.00 74.80 ? 23 THR D O 1 ATOM 4073 C CB . THR D 4 23 ? 44.719 -26.049 56.646 1.00 72.80 ? 23 THR D CB 1 ATOM 4074 O OG1 . THR D 4 23 ? 44.165 -25.213 57.672 1.00 71.42 ? 23 THR D OG1 1 ATOM 4075 C CG2 . THR D 4 23 ? 46.234 -26.078 56.814 1.00 72.08 ? 23 THR D CG2 1 ATOM 4076 N N . VAL D 4 24 ? 43.785 -27.303 53.730 1.00 73.07 ? 24 VAL D N 1 ATOM 4077 C CA . VAL D 4 24 ? 42.970 -28.043 52.763 1.00 71.54 ? 24 VAL D CA 1 ATOM 4078 C C . VAL D 4 24 ? 43.402 -29.518 52.754 1.00 71.46 ? 24 VAL D C 1 ATOM 4079 O O . VAL D 4 24 ? 44.573 -29.823 52.991 1.00 73.22 ? 24 VAL D O 1 ATOM 4080 C CB . VAL D 4 24 ? 43.111 -27.357 51.368 1.00 71.35 ? 24 VAL D CB 1 ATOM 4081 C CG1 . VAL D 4 24 ? 42.939 -28.315 50.196 1.00 71.39 ? 24 VAL D CG1 1 ATOM 4082 C CG2 . VAL D 4 24 ? 42.141 -26.186 51.249 1.00 71.04 ? 24 VAL D CG2 1 ATOM 4083 N N . SER D 4 25 ? 42.456 -30.426 52.502 1.00 71.45 ? 25 SER D N 1 ATOM 4084 C CA . SER D 4 25 ? 42.777 -31.849 52.271 1.00 72.95 ? 25 SER D CA 1 ATOM 4085 C C . SER D 4 25 ? 41.747 -32.540 51.367 1.00 73.25 ? 25 SER D C 1 ATOM 4086 O O . SER D 4 25 ? 40.627 -32.047 51.196 1.00 72.03 ? 25 SER D O 1 ATOM 4087 C CB . SER D 4 25 ? 42.907 -32.605 53.600 1.00 73.80 ? 25 SER D CB 1 ATOM 4088 O OG . SER D 4 25 ? 41.646 -32.798 54.216 1.00 74.19 ? 25 SER D OG 1 ATOM 4089 N N . GLY D 4 26 ? 42.150 -33.674 50.789 1.00 73.96 ? 26 GLY D N 1 ATOM 4090 C CA . GLY D 4 26 ? 41.314 -34.439 49.851 1.00 74.84 ? 26 GLY D CA 1 ATOM 4091 C C . GLY D 4 26 ? 41.665 -34.231 48.385 1.00 77.45 ? 26 GLY D C 1 ATOM 4092 O O . GLY D 4 26 ? 41.449 -35.127 47.566 1.00 78.99 ? 26 GLY D O 1 ATOM 4093 N N . PHE D 4 27 ? 42.199 -33.051 48.057 1.00 77.87 ? 27 PHE D N 1 ATOM 4094 C CA . PHE D 4 27 ? 42.548 -32.673 46.685 1.00 74.32 ? 27 PHE D CA 1 ATOM 4095 C C . PHE D 4 27 ? 43.818 -31.828 46.646 1.00 75.07 ? 27 PHE D C 1 ATOM 4096 O O . PHE D 4 27 ? 44.272 -31.322 47.680 1.00 75.04 ? 27 PHE D O 1 ATOM 4097 C CB . PHE D 4 27 ? 41.397 -31.880 46.051 1.00 73.22 ? 27 PHE D CB 1 ATOM 4098 C CG . PHE D 4 27 ? 41.079 -30.580 46.755 1.00 69.69 ? 27 PHE D CG 1 ATOM 4099 C CD1 . PHE D 4 27 ? 40.283 -30.563 47.901 1.00 69.73 ? 27 PHE D CD1 1 ATOM 4100 C CD2 . PHE D 4 27 ? 41.558 -29.368 46.263 1.00 66.37 ? 27 PHE D CD2 1 ATOM 4101 C CE1 . PHE D 4 27 ? 39.984 -29.366 48.544 1.00 69.16 ? 27 PHE D CE1 1 ATOM 4102 C CE2 . PHE D 4 27 ? 41.262 -28.169 46.902 1.00 65.36 ? 27 PHE D CE2 1 ATOM 4103 C CZ . PHE D 4 27 ? 40.473 -28.166 48.041 1.00 65.88 ? 27 PHE D CZ 1 ATOM 4104 N N . SER D 4 28 ? 44.375 -31.678 45.445 1.00 74.79 ? 28 SER D N 1 ATOM 4105 C CA . SER D 4 28 ? 45.527 -30.809 45.215 1.00 74.58 ? 28 SER D CA 1 ATOM 4106 C C . SER D 4 28 ? 45.071 -29.448 44.696 1.00 74.53 ? 28 SER D C 1 ATOM 4107 O O . SER D 4 28 ? 44.126 -29.352 43.911 1.00 74.14 ? 28 SER D O 1 ATOM 4108 C CB . SER D 4 28 ? 46.498 -31.443 44.218 1.00 75.31 ? 28 SER D CB 1 ATOM 4109 O OG . SER D 4 28 ? 46.002 -31.373 42.894 1.00 78.27 ? 28 SER D OG 1 ATOM 4110 N N . LEU D 4 29 ? 45.777 -28.405 45.121 1.00 75.41 ? 29 LEU D N 1 ATOM 4111 C CA . LEU D 4 29 ? 45.495 -27.036 44.690 1.00 74.01 ? 29 LEU D CA 1 ATOM 4112 C C . LEU D 4 29 ? 45.943 -26.748 43.250 1.00 73.91 ? 29 LEU D C 1 ATOM 4113 O O . LEU D 4 29 ? 45.529 -25.742 42.675 1.00 76.84 ? 29 LEU D O 1 ATOM 4114 C CB . LEU D 4 29 ? 46.158 -26.037 45.645 1.00 72.93 ? 29 LEU D CB 1 ATOM 4115 C CG . LEU D 4 29 ? 45.740 -26.120 47.116 1.00 72.41 ? 29 LEU D CG 1 ATOM 4116 C CD1 . LEU D 4 29 ? 46.578 -25.168 47.960 1.00 73.63 ? 29 LEU D CD1 1 ATOM 4117 C CD2 . LEU D 4 29 ? 44.258 -25.824 47.274 1.00 70.35 ? 29 LEU D CD2 1 ATOM 4118 N N . THR D 4 30 ? 46.793 -27.610 42.684 1.00 72.12 ? 30 THR D N 1 ATOM 4119 C CA . THR D 4 30 ? 47.231 -27.495 41.287 1.00 72.89 ? 30 THR D CA 1 ATOM 4120 C C . THR D 4 30 ? 46.138 -27.825 40.265 1.00 72.89 ? 30 THR D C 1 ATOM 4121 O O . THR D 4 30 ? 46.205 -27.359 39.122 1.00 74.93 ? 30 THR D O 1 ATOM 4122 C CB . THR D 4 30 ? 48.416 -28.435 40.990 1.00 74.02 ? 30 THR D CB 1 ATOM 4123 O OG1 . THR D 4 30 ? 48.056 -29.781 41.333 1.00 75.30 ? 30 THR D OG1 1 ATOM 4124 C CG2 . THR D 4 30 ? 49.654 -28.011 41.771 1.00 73.84 ? 30 THR D CG2 1 ATOM 4125 N N . SER D 4 31 ? 45.169 -28.653 40.663 1.00 70.04 ? 31 SER D N 1 ATOM 4126 C CA . SER D 4 31 ? 44.032 -29.021 39.809 1.00 70.01 ? 31 SER D CA 1 ATOM 4127 C C . SER D 4 31 ? 42.695 -28.347 40.190 1.00 66.32 ? 31 SER D C 1 ATOM 4128 O O . SER D 4 31 ? 41.757 -28.352 39.386 1.00 67.10 ? 31 SER D O 1 ATOM 4129 C CB . SER D 4 31 ? 43.874 -30.548 39.788 1.00 71.15 ? 31 SER D CB 1 ATOM 4130 O OG . SER D 4 31 ? 43.871 -31.074 41.101 1.00 72.52 ? 31 SER D OG 1 ATOM 4131 N N . TYR D 4 32 ? 42.606 -27.771 41.390 1.00 61.84 ? 32 TYR D N 1 ATOM 4132 C CA . TYR D 4 32 ? 41.390 -27.090 41.842 1.00 60.59 ? 32 TYR D CA 1 ATOM 4133 C C . TYR D 4 32 ? 41.681 -25.672 42.308 1.00 58.80 ? 32 TYR D C 1 ATOM 4134 O O . TYR D 4 32 ? 42.633 -25.451 43.064 1.00 59.17 ? 32 TYR D O 1 ATOM 4135 C CB . TYR D 4 32 ? 40.743 -27.876 42.981 1.00 61.08 ? 32 TYR D CB 1 ATOM 4136 C CG . TYR D 4 32 ? 39.909 -29.042 42.506 1.00 62.63 ? 32 TYR D CG 1 ATOM 4137 C CD1 . TYR D 4 32 ? 38.645 -28.836 41.961 1.00 63.39 ? 32 TYR D CD1 1 ATOM 4138 C CD2 . TYR D 4 32 ? 40.380 -30.350 42.596 1.00 63.04 ? 32 TYR D CD2 1 ATOM 4139 C CE1 . TYR D 4 32 ? 37.874 -29.898 41.521 1.00 63.68 ? 32 TYR D CE1 1 ATOM 4140 C CE2 . TYR D 4 32 ? 39.613 -31.419 42.160 1.00 63.39 ? 32 TYR D CE2 1 ATOM 4141 C CZ . TYR D 4 32 ? 38.363 -31.186 41.623 1.00 63.48 ? 32 TYR D CZ 1 ATOM 4142 O OH . TYR D 4 32 ? 37.599 -32.239 41.191 1.00 66.03 ? 32 TYR D OH 1 ATOM 4143 N N . SER D 4 33 ? 40.853 -24.720 41.866 1.00 54.89 ? 33 SER D N 1 ATOM 4144 C CA . SER D 4 33 ? 40.941 -23.333 42.336 1.00 52.44 ? 33 SER D CA 1 ATOM 4145 C C . SER D 4 33 ? 40.372 -23.227 43.745 1.00 51.04 ? 33 SER D C 1 ATOM 4146 O O . SER D 4 33 ? 39.607 -24.090 44.189 1.00 52.85 ? 33 SER D O 1 ATOM 4147 C CB . SER D 4 33 ? 40.196 -22.366 41.399 1.00 51.08 ? 33 SER D CB 1 ATOM 4148 O OG . SER D 4 33 ? 40.788 -22.319 40.108 1.00 49.23 ? 33 SER D OG 1 ATOM 4149 N N . VAL D 4 34 ? 40.760 -22.168 44.444 1.00 50.16 ? 34 VAL D N 1 ATOM 4150 C CA . VAL D 4 34 ? 40.252 -21.877 45.782 1.00 49.86 ? 34 VAL D CA 1 ATOM 4151 C C . VAL D 4 34 ? 39.921 -20.395 45.860 1.00 50.58 ? 34 VAL D C 1 ATOM 4152 O O . VAL D 4 34 ? 40.769 -19.557 45.543 1.00 50.82 ? 34 VAL D O 1 ATOM 4153 C CB . VAL D 4 34 ? 41.284 -22.240 46.873 1.00 49.26 ? 34 VAL D CB 1 ATOM 4154 C CG1 . VAL D 4 34 ? 40.846 -21.739 48.245 1.00 50.28 ? 34 VAL D CG1 1 ATOM 4155 C CG2 . VAL D 4 34 ? 41.506 -23.742 46.909 1.00 49.50 ? 34 VAL D CG2 1 ATOM 4156 N N . SER D 4 35 ? 38.697 -20.089 46.294 1.00 52.31 ? 35 SER D N 1 ATOM 4157 C CA . SER D 4 35 ? 38.228 -18.705 46.463 1.00 53.77 ? 35 SER D CA 1 ATOM 4158 C C . SER D 4 35 ? 38.131 -18.307 47.940 1.00 55.32 ? 35 SER D C 1 ATOM 4159 O O . SER D 4 35 ? 38.129 -19.158 48.822 1.00 55.04 ? 35 SER D O 1 ATOM 4160 C CB . SER D 4 35 ? 36.873 -18.503 45.763 1.00 52.78 ? 35 SER D CB 1 ATOM 4161 O OG . SER D 4 35 ? 37.049 -18.094 44.420 1.00 51.06 ? 35 SER D OG 1 ATOM 4162 N N . TRP D 4 36 ? 38.074 -16.997 48.179 1.00 58.79 ? 36 TRP D N 1 ATOM 4163 C CA . TRP D 4 36 ? 37.844 -16.418 49.501 1.00 60.09 ? 36 TRP D CA 1 ATOM 4164 C C . TRP D 4 36 ? 36.549 -15.614 49.471 1.00 60.61 ? 36 TRP D C 1 ATOM 4165 O O . TRP D 4 36 ? 36.376 -14.736 48.615 1.00 55.08 ? 36 TRP D O 1 ATOM 4166 C CB . TRP D 4 36 ? 39.000 -15.495 49.893 1.00 62.40 ? 36 TRP D CB 1 ATOM 4167 C CG . TRP D 4 36 ? 40.219 -16.211 50.373 1.00 63.71 ? 36 TRP D CG 1 ATOM 4168 C CD1 . TRP D 4 36 ? 41.362 -16.449 49.668 1.00 64.50 ? 36 TRP D CD1 1 ATOM 4169 C CD2 . TRP D 4 36 ? 40.422 -16.777 51.672 1.00 64.56 ? 36 TRP D CD2 1 ATOM 4170 N NE1 . TRP D 4 36 ? 42.266 -17.135 50.448 1.00 65.15 ? 36 TRP D NE1 1 ATOM 4171 C CE2 . TRP D 4 36 ? 41.715 -17.348 51.683 1.00 64.47 ? 36 TRP D CE2 1 ATOM 4172 C CE3 . TRP D 4 36 ? 39.633 -16.864 52.829 1.00 65.92 ? 36 TRP D CE3 1 ATOM 4173 C CZ2 . TRP D 4 36 ? 42.242 -17.994 52.807 1.00 65.73 ? 36 TRP D CZ2 1 ATOM 4174 C CZ3 . TRP D 4 36 ? 40.158 -17.509 53.952 1.00 66.30 ? 36 TRP D CZ3 1 ATOM 4175 C CH2 . TRP D 4 36 ? 41.453 -18.065 53.929 1.00 66.27 ? 36 TRP D CH2 1 ATOM 4176 N N . LEU D 4 37 ? 35.649 -15.928 50.404 1.00 64.54 ? 37 LEU D N 1 ATOM 4177 C CA . LEU D 4 37 ? 34.384 -15.209 50.578 1.00 67.15 ? 37 LEU D CA 1 ATOM 4178 C C . LEU D 4 37 ? 34.316 -14.656 51.995 1.00 66.75 ? 37 LEU D C 1 ATOM 4179 O O . LEU D 4 37 ? 35.043 -15.108 52.887 1.00 64.26 ? 37 LEU D O 1 ATOM 4180 C CB . LEU D 4 37 ? 33.188 -16.145 50.355 1.00 68.71 ? 37 LEU D CB 1 ATOM 4181 C CG . LEU D 4 37 ? 33.226 -17.111 49.171 1.00 70.31 ? 37 LEU D CG 1 ATOM 4182 C CD1 . LEU D 4 37 ? 32.066 -18.088 49.230 1.00 71.36 ? 37 LEU D CD1 1 ATOM 4183 C CD2 . LEU D 4 37 ? 33.210 -16.335 47.872 1.00 72.29 ? 37 LEU D CD2 1 ATOM 4184 N N . ARG D 4 38 ? 33.429 -13.687 52.196 1.00 67.15 ? 38 ARG D N 1 ATOM 4185 C CA . ARG D 4 38 ? 33.123 -13.187 53.530 1.00 71.92 ? 38 ARG D CA 1 ATOM 4186 C C . ARG D 4 38 ? 31.694 -12.659 53.617 1.00 76.37 ? 38 ARG D C 1 ATOM 4187 O O . ARG D 4 38 ? 31.130 -12.222 52.610 1.00 74.22 ? 38 ARG D O 1 ATOM 4188 C CB . ARG D 4 38 ? 34.107 -12.085 53.930 1.00 72.56 ? 38 ARG D CB 1 ATOM 4189 C CG . ARG D 4 38 ? 34.017 -10.825 53.078 1.00 73.02 ? 38 ARG D CG 1 ATOM 4190 C CD . ARG D 4 38 ? 34.780 -9.671 53.692 1.00 73.12 ? 38 ARG D CD 1 ATOM 4191 N NE . ARG D 4 38 ? 34.388 -8.393 53.103 1.00 72.98 ? 38 ARG D NE 1 ATOM 4192 C CZ . ARG D 4 38 ? 34.958 -7.222 53.381 1.00 73.73 ? 38 ARG D CZ 1 ATOM 4193 N NH1 . ARG D 4 38 ? 35.970 -7.137 54.248 1.00 73.42 ? 38 ARG D NH1 1 ATOM 4194 N NH2 . ARG D 4 38 ? 34.515 -6.121 52.783 1.00 74.17 ? 38 ARG D NH2 1 ATOM 4195 N N . GLN D 4 39 ? 31.131 -12.685 54.827 1.00 82.13 ? 39 GLN D N 1 ATOM 4196 C CA . GLN D 4 39 ? 29.801 -12.129 55.097 1.00 84.61 ? 39 GLN D CA 1 ATOM 4197 C C . GLN D 4 39 ? 29.898 -11.045 56.177 1.00 90.00 ? 39 GLN D C 1 ATOM 4198 O O . GLN D 4 39 ? 30.019 -11.359 57.366 1.00 86.11 ? 39 GLN D O 1 ATOM 4199 C CB . GLN D 4 39 ? 28.834 -13.240 55.518 1.00 81.99 ? 39 GLN D CB 1 ATOM 4200 C CG . GLN D 4 39 ? 27.375 -12.808 55.621 1.00 77.94 ? 39 GLN D CG 1 ATOM 4201 C CD . GLN D 4 39 ? 26.419 -13.988 55.716 1.00 76.18 ? 39 GLN D CD 1 ATOM 4202 O OE1 . GLN D 4 39 ? 26.813 -15.100 56.078 1.00 72.48 ? 39 GLN D OE1 1 ATOM 4203 N NE2 . GLN D 4 39 ? 25.153 -13.750 55.385 1.00 74.56 ? 39 GLN D NE2 1 ATOM 4204 N N . PRO D 4 40 ? 29.882 -9.761 55.761 1.00 97.63 ? 40 PRO D N 1 ATOM 4205 C CA . PRO D 4 40 ? 29.733 -8.652 56.708 1.00 101.32 ? 40 PRO D CA 1 ATOM 4206 C C . PRO D 4 40 ? 28.424 -8.709 57.514 1.00 104.53 ? 40 PRO D C 1 ATOM 4207 O O . PRO D 4 40 ? 27.402 -9.182 57.004 1.00 105.24 ? 40 PRO D O 1 ATOM 4208 C CB . PRO D 4 40 ? 29.766 -7.415 55.804 1.00 100.78 ? 40 PRO D CB 1 ATOM 4209 C CG . PRO D 4 40 ? 30.597 -7.832 54.642 1.00 99.83 ? 40 PRO D CG 1 ATOM 4210 C CD . PRO D 4 40 ? 30.255 -9.276 54.416 1.00 98.96 ? 40 PRO D CD 1 ATOM 4211 N N . SER D 4 41 ? 28.476 -8.222 58.756 1.00 105.34 ? 41 SER D N 1 ATOM 4212 C CA . SER D 4 41 ? 27.354 -8.314 59.705 1.00 102.92 ? 41 SER D CA 1 ATOM 4213 C C . SER D 4 41 ? 26.168 -7.437 59.296 1.00 103.50 ? 41 SER D C 1 ATOM 4214 O O . SER D 4 41 ? 26.329 -6.240 59.050 1.00 101.76 ? 41 SER D O 1 ATOM 4215 C CB . SER D 4 41 ? 27.815 -7.920 61.109 1.00 101.53 ? 41 SER D CB 1 ATOM 4216 O OG . SER D 4 41 ? 28.983 -8.632 61.479 1.00 102.88 ? 41 SER D OG 1 ATOM 4217 N N . GLY D 4 42 ? 24.981 -8.039 59.241 1.00 104.38 ? 42 GLY D N 1 ATOM 4218 C CA . GLY D 4 42 ? 23.781 -7.362 58.748 1.00 106.43 ? 42 GLY D CA 1 ATOM 4219 C C . GLY D 4 42 ? 23.793 -7.125 57.245 1.00 108.87 ? 42 GLY D C 1 ATOM 4220 O O . GLY D 4 42 ? 23.176 -6.172 56.759 1.00 111.80 ? 42 GLY D O 1 ATOM 4221 N N . LYS D 4 43 ? 24.493 -7.995 56.512 1.00 108.23 ? 43 LYS D N 1 ATOM 4222 C CA . LYS D 4 43 ? 24.627 -7.899 55.052 1.00 104.87 ? 43 LYS D CA 1 ATOM 4223 C C . LYS D 4 43 ? 24.769 -9.293 54.446 1.00 97.55 ? 43 LYS D C 1 ATOM 4224 O O . LYS D 4 43 ? 24.918 -10.279 55.172 1.00 98.30 ? 43 LYS D O 1 ATOM 4225 C CB . LYS D 4 43 ? 25.851 -7.051 54.681 1.00 107.93 ? 43 LYS D CB 1 ATOM 4226 C CG . LYS D 4 43 ? 25.682 -5.555 54.887 1.00 108.95 ? 43 LYS D CG 1 ATOM 4227 C CD . LYS D 4 43 ? 26.897 -4.792 54.385 1.00 109.05 ? 43 LYS D CD 1 ATOM 4228 C CE . LYS D 4 43 ? 26.665 -3.292 54.436 1.00 109.55 ? 43 LYS D CE 1 ATOM 4229 N NZ . LYS D 4 43 ? 27.809 -2.533 53.862 1.00 110.11 ? 43 LYS D NZ 1 ATOM 4230 N N . GLY D 4 44 ? 24.731 -9.366 53.117 1.00 91.01 ? 44 GLY D N 1 ATOM 4231 C CA . GLY D 4 44 ? 24.920 -10.629 52.399 1.00 87.24 ? 44 GLY D CA 1 ATOM 4232 C C . GLY D 4 44 ? 26.386 -11.030 52.275 1.00 81.47 ? 44 GLY D C 1 ATOM 4233 O O . GLY D 4 44 ? 27.276 -10.255 52.651 1.00 80.24 ? 44 GLY D O 1 ATOM 4234 N N . PRO D 4 45 ? 26.654 -12.250 51.761 1.00 75.13 ? 45 PRO D N 1 ATOM 4235 C CA . PRO D 4 45 ? 28.034 -12.606 51.409 1.00 71.88 ? 45 PRO D CA 1 ATOM 4236 C C . PRO D 4 45 ? 28.547 -11.883 50.155 1.00 68.41 ? 45 PRO D C 1 ATOM 4237 O O . PRO D 4 45 ? 27.752 -11.320 49.387 1.00 65.46 ? 45 PRO D O 1 ATOM 4238 C CB . PRO D 4 45 ? 27.964 -14.126 51.166 1.00 72.25 ? 45 PRO D CB 1 ATOM 4239 C CG . PRO D 4 45 ? 26.718 -14.579 51.842 1.00 72.22 ? 45 PRO D CG 1 ATOM 4240 C CD . PRO D 4 45 ? 25.766 -13.427 51.713 1.00 73.54 ? 45 PRO D CD 1 ATOM 4241 N N . GLU D 4 46 ? 29.869 -11.897 49.972 1.00 66.91 ? 46 GLU D N 1 ATOM 4242 C CA . GLU D 4 46 ? 30.512 -11.391 48.746 1.00 67.80 ? 46 GLU D CA 1 ATOM 4243 C C . GLU D 4 46 ? 31.870 -12.064 48.480 1.00 65.30 ? 46 GLU D C 1 ATOM 4244 O O . GLU D 4 46 ? 32.616 -12.374 49.414 1.00 67.29 ? 46 GLU D O 1 ATOM 4245 C CB . GLU D 4 46 ? 30.667 -9.861 48.781 1.00 69.66 ? 46 GLU D CB 1 ATOM 4246 C CG . GLU D 4 46 ? 31.764 -9.318 49.700 1.00 72.16 ? 46 GLU D CG 1 ATOM 4247 C CD . GLU D 4 46 ? 31.875 -7.799 49.663 1.00 74.49 ? 46 GLU D CD 1 ATOM 4248 O OE1 . GLU D 4 46 ? 31.551 -7.190 48.615 1.00 72.65 ? 46 GLU D OE1 1 ATOM 4249 O OE2 . GLU D 4 46 ? 32.298 -7.212 50.686 1.00 74.85 ? 46 GLU D OE2 1 ATOM 4250 N N . TRP D 4 47 ? 32.178 -12.269 47.198 1.00 60.59 ? 47 TRP D N 1 ATOM 4251 C CA . TRP D 4 47 ? 33.419 -12.931 46.776 1.00 55.94 ? 47 TRP D CA 1 ATOM 4252 C C . TRP D 4 47 ? 34.587 -11.938 46.834 1.00 57.14 ? 47 TRP D C 1 ATOM 4253 O O . TRP D 4 47 ? 34.531 -10.862 46.228 1.00 57.68 ? 47 TRP D O 1 ATOM 4254 C CB . TRP D 4 47 ? 33.240 -13.531 45.370 1.00 51.59 ? 47 TRP D CB 1 ATOM 4255 C CG . TRP D 4 47 ? 34.476 -14.090 44.721 1.00 47.16 ? 47 TRP D CG 1 ATOM 4256 C CD1 . TRP D 4 47 ? 35.087 -15.286 44.990 1.00 45.94 ? 47 TRP D CD1 1 ATOM 4257 C CD2 . TRP D 4 47 ? 35.231 -13.482 43.671 1.00 44.15 ? 47 TRP D CD2 1 ATOM 4258 N NE1 . TRP D 4 47 ? 36.186 -15.450 44.180 1.00 45.05 ? 47 TRP D NE1 1 ATOM 4259 C CE2 . TRP D 4 47 ? 36.296 -14.358 43.359 1.00 44.79 ? 47 TRP D CE2 1 ATOM 4260 C CE3 . TRP D 4 47 ? 35.118 -12.275 42.967 1.00 44.26 ? 47 TRP D CE3 1 ATOM 4261 C CZ2 . TRP D 4 47 ? 37.244 -14.066 42.370 1.00 44.85 ? 47 TRP D CZ2 1 ATOM 4262 C CZ3 . TRP D 4 47 ? 36.061 -11.981 41.980 1.00 44.40 ? 47 TRP D CZ3 1 ATOM 4263 C CH2 . TRP D 4 47 ? 37.112 -12.876 41.694 1.00 44.80 ? 47 TRP D CH2 1 ATOM 4264 N N . MET D 4 48 ? 35.632 -12.299 47.577 1.00 56.72 ? 48 MET D N 1 ATOM 4265 C CA . MET D 4 48 ? 36.794 -11.430 47.761 1.00 57.03 ? 48 MET D CA 1 ATOM 4266 C C . MET D 4 48 ? 37.800 -11.600 46.629 1.00 54.91 ? 48 MET D C 1 ATOM 4267 O O . MET D 4 48 ? 38.269 -10.622 46.058 1.00 56.16 ? 48 MET D O 1 ATOM 4268 C CB . MET D 4 48 ? 37.466 -11.718 49.102 1.00 59.92 ? 48 MET D CB 1 ATOM 4269 C CG . MET D 4 48 ? 36.554 -11.523 50.311 1.00 60.89 ? 48 MET D CG 1 ATOM 4270 S SD . MET D 4 48 ? 37.390 -11.881 51.871 1.00 62.54 ? 48 MET D SD 1 ATOM 4271 C CE . MET D 4 48 ? 38.386 -10.403 52.045 1.00 63.08 ? 48 MET D CE 1 ATOM 4272 N N . GLY D 4 49 ? 38.132 -12.844 46.309 1.00 52.57 ? 49 GLY D N 1 ATOM 4273 C CA . GLY D 4 49 ? 39.078 -13.131 45.237 1.00 51.18 ? 49 GLY D CA 1 ATOM 4274 C C . GLY D 4 49 ? 39.366 -14.615 45.141 1.00 51.64 ? 49 GLY D C 1 ATOM 4275 O O . GLY D 4 49 ? 38.850 -15.401 45.940 1.00 49.32 ? 49 GLY D O 1 ATOM 4276 N N . ARG D 4 50 ? 40.201 -14.991 44.170 1.00 52.59 ? 50 ARG D N 1 ATOM 4277 C CA . ARG D 4 50 ? 40.505 -16.396 43.888 1.00 53.97 ? 50 ARG D CA 1 ATOM 4278 C C . ARG D 4 50 ? 42.006 -16.637 43.719 1.00 53.68 ? 50 ARG D C 1 ATOM 4279 O O . ARG D 4 50 ? 42.725 -15.800 43.161 1.00 50.43 ? 50 ARG D O 1 ATOM 4280 C CB . ARG D 4 50 ? 39.748 -16.874 42.629 1.00 54.55 ? 50 ARG D CB 1 ATOM 4281 C CG . ARG D 4 50 ? 40.044 -18.314 42.208 1.00 54.61 ? 50 ARG D CG 1 ATOM 4282 C CD . ARG D 4 50 ? 39.316 -18.730 40.940 1.00 55.68 ? 50 ARG D CD 1 ATOM 4283 N NE . ARG D 4 50 ? 37.870 -18.850 41.145 1.00 55.57 ? 50 ARG D NE 1 ATOM 4284 C CZ . ARG D 4 50 ? 36.936 -18.027 40.662 1.00 55.65 ? 50 ARG D CZ 1 ATOM 4285 N NH1 . ARG D 4 50 ? 37.249 -16.977 39.902 1.00 56.62 ? 50 ARG D NH1 1 ATOM 4286 N NH2 . ARG D 4 50 ? 35.657 -18.259 40.944 1.00 55.54 ? 50 ARG D NH2 1 ATOM 4287 N N . MET D 4 51 ? 42.445 -17.793 44.222 1.00 53.49 ? 51 MET D N 1 ATOM 4288 C CA . MET D 4 51 ? 43.740 -18.382 43.909 1.00 53.99 ? 51 MET D CA 1 ATOM 4289 C C . MET D 4 51 ? 43.455 -19.391 42.816 1.00 51.31 ? 51 MET D C 1 ATOM 4290 O O . MET D 4 51 ? 42.796 -20.399 43.067 1.00 50.82 ? 51 MET D O 1 ATOM 4291 C CB . MET D 4 51 ? 44.325 -19.090 45.147 1.00 58.17 ? 51 MET D CB 1 ATOM 4292 C CG . MET D 4 51 ? 45.509 -20.030 44.908 1.00 60.39 ? 51 MET D CG 1 ATOM 4293 S SD . MET D 4 51 ? 46.909 -19.293 44.038 1.00 64.40 ? 51 MET D SD 1 ATOM 4294 C CE . MET D 4 51 ? 47.470 -18.119 45.255 1.00 63.49 ? 51 MET D CE 1 ATOM 4295 N N . TRP D 4 52 ? 43.932 -19.121 41.606 1.00 49.75 ? 52 TRP D N 1 ATOM 4296 C CA . TRP D 4 52 ? 43.706 -20.031 40.483 1.00 50.03 ? 52 TRP D CA 1 ATOM 4297 C C . TRP D 4 52 ? 44.446 -21.353 40.652 1.00 51.04 ? 52 TRP D C 1 ATOM 4298 O O . TRP D 4 52 ? 45.426 -21.438 41.389 1.00 54.60 ? 52 TRP D O 1 ATOM 4299 C CB . TRP D 4 52 ? 44.118 -19.387 39.162 1.00 48.95 ? 52 TRP D CB 1 ATOM 4300 C CG . TRP D 4 52 ? 43.164 -18.356 38.676 1.00 48.11 ? 52 TRP D CG 1 ATOM 4301 C CD1 . TRP D 4 52 ? 43.335 -17.000 38.691 1.00 47.90 ? 52 TRP D CD1 1 ATOM 4302 C CD2 . TRP D 4 52 ? 41.886 -18.593 38.087 1.00 46.99 ? 52 TRP D CD2 1 ATOM 4303 N NE1 . TRP D 4 52 ? 42.239 -16.378 38.144 1.00 47.33 ? 52 TRP D NE1 1 ATOM 4304 C CE2 . TRP D 4 52 ? 41.334 -17.334 37.765 1.00 47.57 ? 52 TRP D CE2 1 ATOM 4305 C CE3 . TRP D 4 52 ? 41.154 -19.749 37.793 1.00 47.08 ? 52 TRP D CE3 1 ATOM 4306 C CZ2 . TRP D 4 52 ? 40.078 -17.200 37.165 1.00 47.77 ? 52 TRP D CZ2 1 ATOM 4307 C CZ3 . TRP D 4 52 ? 39.902 -19.614 37.195 1.00 47.06 ? 52 TRP D CZ3 1 ATOM 4308 C CH2 . TRP D 4 52 ? 39.379 -18.349 36.890 1.00 47.43 ? 52 TRP D CH2 1 ATOM 4309 N N . ASP D 4 53 ? 43.955 -22.379 39.963 1.00 51.99 ? 53 ASP D N 1 ATOM 4310 C CA . ASP D 4 53 ? 44.631 -23.679 39.906 1.00 53.05 ? 53 ASP D CA 1 ATOM 4311 C C . ASP D 4 53 ? 46.021 -23.609 39.255 1.00 54.65 ? 53 ASP D C 1 ATOM 4312 O O . ASP D 4 53 ? 46.894 -24.408 39.583 1.00 61.29 ? 53 ASP D O 1 ATOM 4313 C CB . ASP D 4 53 ? 43.757 -24.727 39.193 1.00 53.87 ? 53 ASP D CB 1 ATOM 4314 C CG . ASP D 4 53 ? 43.476 -24.386 37.723 1.00 54.74 ? 53 ASP D CG 1 ATOM 4315 O OD1 . ASP D 4 53 ? 43.357 -23.181 37.380 1.00 52.12 ? 53 ASP D OD1 1 ATOM 4316 O OD2 . ASP D 4 53 ? 43.358 -25.341 36.920 1.00 54.87 ? 53 ASP D OD2 1 ATOM 4317 N N . ASP D 4 54 ? 46.217 -22.659 38.339 1.00 54.80 ? 54 ASP D N 1 ATOM 4318 C CA . ASP D 4 54 ? 47.518 -22.439 37.673 1.00 53.72 ? 54 ASP D CA 1 ATOM 4319 C C . ASP D 4 54 ? 48.504 -21.512 38.424 1.00 52.29 ? 54 ASP D C 1 ATOM 4320 O O . ASP D 4 54 ? 49.535 -21.130 37.865 1.00 52.01 ? 54 ASP D O 1 ATOM 4321 C CB . ASP D 4 54 ? 47.295 -21.918 36.243 1.00 53.25 ? 54 ASP D CB 1 ATOM 4322 C CG . ASP D 4 54 ? 46.601 -20.565 36.206 1.00 54.23 ? 54 ASP D CG 1 ATOM 4323 O OD1 . ASP D 4 54 ? 47.082 -19.604 36.846 1.00 53.03 ? 54 ASP D OD1 1 ATOM 4324 O OD2 . ASP D 4 54 ? 45.558 -20.465 35.529 1.00 57.02 ? 54 ASP D OD2 1 ATOM 4325 N N . GLY D 4 55 ? 48.178 -21.122 39.656 1.00 52.09 ? 55 GLY D N 1 ATOM 4326 C CA . GLY D 4 55 ? 49.084 -20.317 40.486 1.00 52.39 ? 55 GLY D CA 1 ATOM 4327 C C . GLY D 4 55 ? 48.784 -18.829 40.543 1.00 50.64 ? 55 GLY D C 1 ATOM 4328 O O . GLY D 4 55 ? 49.066 -18.190 41.553 1.00 50.22 ? 55 GLY D O 1 ATOM 4329 N N . GLY D 4 56 ? 48.220 -18.269 39.473 1.00 49.80 ? 56 GLY D N 1 ATOM 4330 C CA . GLY D 4 56 ? 47.866 -16.847 39.438 1.00 49.57 ? 56 GLY D CA 1 ATOM 4331 C C . GLY D 4 56 ? 46.679 -16.501 40.322 1.00 49.23 ? 56 GLY D C 1 ATOM 4332 O O . GLY D 4 56 ? 46.141 -17.370 41.009 1.00 53.21 ? 56 GLY D O 1 ATOM 4333 N N . THR D 4 57 ? 46.281 -15.229 40.319 1.00 47.42 ? 57 THR D N 1 ATOM 4334 C CA . THR D 4 57 ? 45.197 -14.750 41.177 1.00 48.52 ? 57 THR D CA 1 ATOM 4335 C C . THR D 4 57 ? 44.304 -13.725 40.475 1.00 48.18 ? 57 THR D C 1 ATOM 4336 O O . THR D 4 57 ? 44.682 -13.139 39.468 1.00 51.22 ? 57 THR D O 1 ATOM 4337 C CB . THR D 4 57 ? 45.734 -14.134 42.501 1.00 50.75 ? 57 THR D CB 1 ATOM 4338 O OG1 . THR D 4 57 ? 46.366 -12.871 42.248 1.00 53.01 ? 57 THR D OG1 1 ATOM 4339 C CG2 . THR D 4 57 ? 46.735 -15.063 43.191 1.00 50.70 ? 57 THR D CG2 1 ATOM 4340 N N . VAL D 4 58 ? 43.109 -13.537 41.023 1.00 48.25 ? 58 VAL D N 1 ATOM 4341 C CA . VAL D 4 58 ? 42.172 -12.504 40.576 1.00 47.82 ? 58 VAL D CA 1 ATOM 4342 C C . VAL D 4 58 ? 41.403 -11.987 41.796 1.00 48.29 ? 58 VAL D C 1 ATOM 4343 O O . VAL D 4 58 ? 41.097 -12.762 42.706 1.00 47.81 ? 58 VAL D O 1 ATOM 4344 C CB . VAL D 4 58 ? 41.199 -13.034 39.493 1.00 47.03 ? 58 VAL D CB 1 ATOM 4345 C CG1 . VAL D 4 58 ? 40.422 -14.256 39.978 1.00 45.87 ? 58 VAL D CG1 1 ATOM 4346 C CG2 . VAL D 4 58 ? 40.242 -11.939 39.039 1.00 47.67 ? 58 VAL D CG2 1 ATOM 4347 N N . TYR D 4 59 ? 41.104 -10.687 41.809 1.00 49.01 ? 59 TYR D N 1 ATOM 4348 C CA . TYR D 4 59 ? 40.486 -10.038 42.961 1.00 50.58 ? 59 TYR D CA 1 ATOM 4349 C C . TYR D 4 59 ? 39.228 -9.273 42.589 1.00 50.95 ? 59 TYR D C 1 ATOM 4350 O O . TYR D 4 59 ? 39.094 -8.762 41.475 1.00 51.19 ? 59 TYR D O 1 ATOM 4351 C CB . TYR D 4 59 ? 41.471 -9.064 43.628 1.00 52.24 ? 59 TYR D CB 1 ATOM 4352 C CG . TYR D 4 59 ? 42.796 -9.690 43.991 1.00 53.01 ? 59 TYR D CG 1 ATOM 4353 C CD1 . TYR D 4 59 ? 42.965 -10.381 45.194 1.00 53.14 ? 59 TYR D CD1 1 ATOM 4354 C CD2 . TYR D 4 59 ? 43.881 -9.607 43.120 1.00 53.49 ? 59 TYR D CD2 1 ATOM 4355 C CE1 . TYR D 4 59 ? 44.182 -10.963 45.518 1.00 53.91 ? 59 TYR D CE1 1 ATOM 4356 C CE2 . TYR D 4 59 ? 45.099 -10.186 43.433 1.00 54.09 ? 59 TYR D CE2 1 ATOM 4357 C CZ . TYR D 4 59 ? 45.248 -10.862 44.628 1.00 55.52 ? 59 TYR D CZ 1 ATOM 4358 O OH . TYR D 4 59 ? 46.465 -11.440 44.917 1.00 59.04 ? 59 TYR D OH 1 ATOM 4359 N N . ASN D 4 60 ? 38.307 -9.227 43.548 1.00 52.31 ? 60 ASN D N 1 ATOM 4360 C CA . ASN D 4 60 ? 37.241 -8.238 43.607 1.00 53.75 ? 60 ASN D CA 1 ATOM 4361 C C . ASN D 4 60 ? 37.906 -6.881 43.393 1.00 58.61 ? 60 ASN D C 1 ATOM 4362 O O . ASN D 4 60 ? 38.791 -6.498 44.166 1.00 60.46 ? 60 ASN D O 1 ATOM 4363 C CB . ASN D 4 60 ? 36.579 -8.318 44.994 1.00 52.86 ? 60 ASN D CB 1 ATOM 4364 C CG . ASN D 4 60 ? 35.346 -7.448 45.134 1.00 52.97 ? 60 ASN D CG 1 ATOM 4365 O OD1 . ASN D 4 60 ? 35.305 -6.297 44.695 1.00 53.37 ? 60 ASN D OD1 1 ATOM 4366 N ND2 . ASN D 4 60 ? 34.332 -7.996 45.788 1.00 53.21 ? 60 ASN D ND2 1 ATOM 4367 N N . SER D 4 61 ? 37.505 -6.170 42.339 1.00 63.99 ? 61 SER D N 1 ATOM 4368 C CA . SER D 4 61 ? 38.127 -4.881 41.983 1.00 67.61 ? 61 SER D CA 1 ATOM 4369 C C . SER D 4 61 ? 38.020 -3.812 43.087 1.00 70.32 ? 61 SER D C 1 ATOM 4370 O O . SER D 4 61 ? 38.876 -2.930 43.170 1.00 75.28 ? 61 SER D O 1 ATOM 4371 C CB . SER D 4 61 ? 37.549 -4.343 40.671 1.00 66.47 ? 61 SER D CB 1 ATOM 4372 O OG . SER D 4 61 ? 36.143 -4.215 40.757 1.00 66.25 ? 61 SER D OG 1 ATOM 4373 N N . GLY D 4 62 ? 36.979 -3.895 43.917 1.00 69.02 ? 62 GLY D N 1 ATOM 4374 C CA . GLY D 4 62 ? 36.815 -3.007 45.069 1.00 69.33 ? 62 GLY D CA 1 ATOM 4375 C C . GLY D 4 62 ? 37.822 -3.207 46.191 1.00 69.22 ? 62 GLY D C 1 ATOM 4376 O O . GLY D 4 62 ? 38.151 -2.253 46.892 1.00 70.07 ? 62 GLY D O 1 ATOM 4377 N N . LEU D 4 63 ? 38.303 -4.441 46.358 1.00 69.14 ? 63 LEU D N 1 ATOM 4378 C CA . LEU D 4 63 ? 39.288 -4.794 47.392 1.00 71.23 ? 63 LEU D CA 1 ATOM 4379 C C . LEU D 4 63 ? 40.704 -4.991 46.828 1.00 73.61 ? 63 LEU D C 1 ATOM 4380 O O . LEU D 4 63 ? 41.585 -5.516 47.524 1.00 70.86 ? 63 LEU D O 1 ATOM 4381 C CB . LEU D 4 63 ? 38.855 -6.092 48.087 1.00 72.88 ? 63 LEU D CB 1 ATOM 4382 C CG . LEU D 4 63 ? 37.444 -6.156 48.676 1.00 73.89 ? 63 LEU D CG 1 ATOM 4383 C CD1 . LEU D 4 63 ? 37.148 -7.555 49.197 1.00 73.28 ? 63 LEU D CD1 1 ATOM 4384 C CD2 . LEU D 4 63 ? 37.278 -5.121 49.781 1.00 74.58 ? 63 LEU D CD2 1 ATOM 4385 N N . LYS D 4 64 ? 40.927 -4.536 45.594 1.00 75.98 ? 64 LYS D N 1 ATOM 4386 C CA . LYS D 4 64 ? 42.080 -4.955 44.779 1.00 76.41 ? 64 LYS D CA 1 ATOM 4387 C C . LYS D 4 64 ? 43.451 -4.591 45.378 1.00 74.90 ? 64 LYS D C 1 ATOM 4388 O O . LYS D 4 64 ? 44.372 -5.411 45.350 1.00 73.78 ? 64 LYS D O 1 ATOM 4389 C CB . LYS D 4 64 ? 41.933 -4.387 43.356 1.00 76.36 ? 64 LYS D CB 1 ATOM 4390 C CG . LYS D 4 64 ? 42.943 -4.894 42.338 1.00 76.72 ? 64 LYS D CG 1 ATOM 4391 C CD . LYS D 4 64 ? 42.564 -4.456 40.928 1.00 77.45 ? 64 LYS D CD 1 ATOM 4392 C CE . LYS D 4 64 ? 43.784 -4.276 40.034 1.00 77.45 ? 64 LYS D CE 1 ATOM 4393 N NZ . LYS D 4 64 ? 44.731 -5.429 40.078 1.00 77.25 ? 64 LYS D NZ 1 ATOM 4394 N N . SER D 4 65 ? 43.574 -3.379 45.919 1.00 74.99 ? 65 SER D N 1 ATOM 4395 C CA . SER D 4 65 ? 44.835 -2.899 46.515 1.00 76.42 ? 65 SER D CA 1 ATOM 4396 C C . SER D 4 65 ? 45.108 -3.467 47.921 1.00 79.82 ? 65 SER D C 1 ATOM 4397 O O . SER D 4 65 ? 46.265 -3.725 48.278 1.00 78.73 ? 65 SER D O 1 ATOM 4398 C CB . SER D 4 65 ? 44.851 -1.369 46.565 1.00 73.21 ? 65 SER D CB 1 ATOM 4399 O OG . SER D 4 65 ? 43.729 -0.880 47.270 1.00 72.72 ? 65 SER D OG 1 ATOM 4400 N N . ARG D 4 66 ? 44.049 -3.655 48.709 1.00 80.38 ? 66 ARG D N 1 ATOM 4401 C CA . ARG D 4 66 ? 44.170 -4.201 50.067 1.00 78.84 ? 66 ARG D CA 1 ATOM 4402 C C . ARG D 4 66 ? 44.524 -5.691 50.077 1.00 77.78 ? 66 ARG D C 1 ATOM 4403 O O . ARG D 4 66 ? 45.284 -6.142 50.939 1.00 76.16 ? 66 ARG D O 1 ATOM 4404 C CB . ARG D 4 66 ? 42.866 -4.022 50.840 1.00 80.50 ? 66 ARG D CB 1 ATOM 4405 C CG . ARG D 4 66 ? 42.415 -2.583 51.036 1.00 83.47 ? 66 ARG D CG 1 ATOM 4406 C CD . ARG D 4 66 ? 41.015 -2.538 51.627 1.00 85.96 ? 66 ARG D CD 1 ATOM 4407 N NE . ARG D 4 66 ? 40.940 -3.310 52.866 1.00 89.69 ? 66 ARG D NE 1 ATOM 4408 C CZ . ARG D 4 66 ? 39.817 -3.722 53.459 1.00 95.21 ? 66 ARG D CZ 1 ATOM 4409 N NH1 . ARG D 4 66 ? 38.611 -3.445 52.951 1.00 95.68 ? 66 ARG D NH1 1 ATOM 4410 N NH2 . ARG D 4 66 ? 39.906 -4.432 54.584 1.00 95.90 ? 66 ARG D NH2 1 ATOM 4411 N N . LEU D 4 67 ? 43.960 -6.445 49.131 1.00 74.89 ? 67 LEU D N 1 ATOM 4412 C CA . LEU D 4 67 ? 44.109 -7.903 49.099 1.00 73.60 ? 67 LEU D CA 1 ATOM 4413 C C . LEU D 4 67 ? 45.407 -8.380 48.461 1.00 70.92 ? 67 LEU D C 1 ATOM 4414 O O . LEU D 4 67 ? 46.016 -7.681 47.652 1.00 69.45 ? 67 LEU D O 1 ATOM 4415 C CB . LEU D 4 67 ? 42.939 -8.551 48.349 1.00 77.11 ? 67 LEU D CB 1 ATOM 4416 C CG . LEU D 4 67 ? 41.615 -8.679 49.096 1.00 80.23 ? 67 LEU D CG 1 ATOM 4417 C CD1 . LEU D 4 67 ? 40.545 -9.214 48.154 1.00 81.39 ? 67 LEU D CD1 1 ATOM 4418 C CD2 . LEU D 4 67 ? 41.762 -9.582 50.316 1.00 82.37 ? 67 LEU D CD2 1 ATOM 4419 N N . SER D 4 68 ? 45.806 -9.590 48.842 1.00 70.16 ? 68 SER D N 1 ATOM 4420 C CA . SER D 4 68 ? 46.877 -10.326 48.171 1.00 72.30 ? 68 SER D CA 1 ATOM 4421 C C . SER D 4 68 ? 46.835 -11.799 48.603 1.00 70.93 ? 68 SER D C 1 ATOM 4422 O O . SER D 4 68 ? 47.077 -12.112 49.770 1.00 72.82 ? 68 SER D O 1 ATOM 4423 C CB . SER D 4 68 ? 48.251 -9.705 48.451 1.00 74.66 ? 68 SER D CB 1 ATOM 4424 O OG . SER D 4 68 ? 48.362 -9.276 49.795 1.00 81.47 ? 68 SER D OG 1 ATOM 4425 N N . ILE D 4 69 ? 46.515 -12.683 47.655 1.00 66.45 ? 69 ILE D N 1 ATOM 4426 C CA . ILE D 4 69 ? 46.321 -14.110 47.907 1.00 64.50 ? 69 ILE D CA 1 ATOM 4427 C C . ILE D 4 69 ? 47.571 -14.862 47.451 1.00 64.62 ? 69 ILE D C 1 ATOM 4428 O O . ILE D 4 69 ? 48.168 -14.511 46.434 1.00 67.74 ? 69 ILE D O 1 ATOM 4429 C CB . ILE D 4 69 ? 45.075 -14.638 47.150 1.00 64.76 ? 69 ILE D CB 1 ATOM 4430 C CG1 . ILE D 4 69 ? 43.795 -13.980 47.684 1.00 65.96 ? 69 ILE D CG1 1 ATOM 4431 C CG2 . ILE D 4 69 ? 44.949 -16.151 47.275 1.00 63.45 ? 69 ILE D CG2 1 ATOM 4432 C CD1 . ILE D 4 69 ? 42.627 -14.020 46.720 1.00 65.49 ? 69 ILE D CD1 1 ATOM 4433 N N . SER D 4 70 ? 47.961 -15.887 48.209 1.00 63.54 ? 70 SER D N 1 ATOM 4434 C CA . SER D 4 70 ? 49.118 -16.730 47.882 1.00 63.86 ? 70 SER D CA 1 ATOM 4435 C C . SER D 4 70 ? 48.813 -18.181 48.251 1.00 66.05 ? 70 SER D C 1 ATOM 4436 O O . SER D 4 70 ? 47.712 -18.475 48.719 1.00 66.10 ? 70 SER D O 1 ATOM 4437 C CB . SER D 4 70 ? 50.371 -16.229 48.611 1.00 63.42 ? 70 SER D CB 1 ATOM 4438 O OG . SER D 4 70 ? 50.232 -16.315 50.018 1.00 60.70 ? 70 SER D OG 1 ATOM 4439 N N . ARG D 4 71 ? 49.762 -19.086 48.008 1.00 68.56 ? 71 ARG D N 1 ATOM 4440 C CA . ARG D 4 71 ? 49.595 -20.492 48.388 1.00 70.98 ? 71 ARG D CA 1 ATOM 4441 C C . ARG D 4 71 ? 50.916 -21.240 48.564 1.00 71.78 ? 71 ARG D C 1 ATOM 4442 O O . ARG D 4 71 ? 51.975 -20.757 48.171 1.00 73.95 ? 71 ARG D O 1 ATOM 4443 C CB . ARG D 4 71 ? 48.705 -21.228 47.370 1.00 72.87 ? 71 ARG D CB 1 ATOM 4444 C CG . ARG D 4 71 ? 49.283 -21.400 45.967 1.00 73.05 ? 71 ARG D CG 1 ATOM 4445 C CD . ARG D 4 71 ? 48.427 -22.361 45.154 1.00 74.89 ? 71 ARG D CD 1 ATOM 4446 N NE . ARG D 4 71 ? 48.958 -22.615 43.809 1.00 77.21 ? 71 ARG D NE 1 ATOM 4447 C CZ . ARG D 4 71 ? 48.273 -23.154 42.791 1.00 75.45 ? 71 ARG D CZ 1 ATOM 4448 N NH1 . ARG D 4 71 ? 46.990 -23.504 42.923 1.00 74.40 ? 71 ARG D NH1 1 ATOM 4449 N NH2 . ARG D 4 71 ? 48.878 -23.338 41.617 1.00 72.98 ? 71 ARG D NH2 1 ATOM 4450 N N . ASP D 4 72 ? 50.818 -22.426 49.157 1.00 72.12 ? 72 ASP D N 1 ATOM 4451 C CA . ASP D 4 72 ? 51.943 -23.338 49.335 1.00 75.40 ? 72 ASP D CA 1 ATOM 4452 C C . ASP D 4 72 ? 51.416 -24.760 49.126 1.00 78.51 ? 72 ASP D C 1 ATOM 4453 O O . ASP D 4 72 ? 50.757 -25.318 50.009 1.00 81.17 ? 72 ASP D O 1 ATOM 4454 C CB . ASP D 4 72 ? 52.533 -23.156 50.741 1.00 76.26 ? 72 ASP D CB 1 ATOM 4455 C CG . ASP D 4 72 ? 53.884 -23.836 50.916 1.00 75.15 ? 72 ASP D CG 1 ATOM 4456 O OD1 . ASP D 4 72 ? 54.053 -25.005 50.503 1.00 74.11 ? 72 ASP D OD1 1 ATOM 4457 O OD2 . ASP D 4 72 ? 54.783 -23.190 51.489 1.00 74.21 ? 72 ASP D OD2 1 ATOM 4458 N N . THR D 4 73 ? 51.702 -25.338 47.959 1.00 79.07 ? 73 THR D N 1 ATOM 4459 C CA . THR D 4 73 ? 51.067 -26.600 47.545 1.00 82.86 ? 73 THR D CA 1 ATOM 4460 C C . THR D 4 73 ? 51.507 -27.832 48.353 1.00 85.87 ? 73 THR D C 1 ATOM 4461 O O . THR D 4 73 ? 50.756 -28.810 48.440 1.00 83.65 ? 73 THR D O 1 ATOM 4462 C CB . THR D 4 73 ? 51.265 -26.877 46.037 1.00 82.38 ? 73 THR D CB 1 ATOM 4463 O OG1 . THR D 4 73 ? 52.661 -26.958 45.734 1.00 84.65 ? 73 THR D OG1 1 ATOM 4464 C CG2 . THR D 4 73 ? 50.622 -25.774 45.196 1.00 81.10 ? 73 THR D CG2 1 ATOM 4465 N N . SER D 4 74 ? 52.705 -27.779 48.942 1.00 91.44 ? 74 SER D N 1 ATOM 4466 C CA . SER D 4 74 ? 53.196 -28.842 49.835 1.00 93.39 ? 74 SER D CA 1 ATOM 4467 C C . SER D 4 74 ? 52.511 -28.776 51.200 1.00 91.49 ? 74 SER D C 1 ATOM 4468 O O . SER D 4 74 ? 52.117 -29.804 51.752 1.00 88.77 ? 74 SER D O 1 ATOM 4469 C CB . SER D 4 74 ? 54.707 -28.729 50.023 1.00 94.67 ? 74 SER D CB 1 ATOM 4470 O OG . SER D 4 74 ? 55.031 -27.543 50.729 1.00 97.10 ? 74 SER D OG 1 ATOM 4471 N N . LYS D 4 75 ? 52.391 -27.562 51.740 1.00 91.62 ? 75 LYS D N 1 ATOM 4472 C CA . LYS D 4 75 ? 51.633 -27.324 52.979 1.00 93.74 ? 75 LYS D CA 1 ATOM 4473 C C . LYS D 4 75 ? 50.104 -27.389 52.804 1.00 91.81 ? 75 LYS D C 1 ATOM 4474 O O . LYS D 4 75 ? 49.386 -27.444 53.803 1.00 90.62 ? 75 LYS D O 1 ATOM 4475 C CB . LYS D 4 75 ? 52.017 -25.974 53.612 1.00 95.97 ? 75 LYS D CB 1 ATOM 4476 C CG . LYS D 4 75 ? 53.416 -25.939 54.218 1.00 98.95 ? 75 LYS D CG 1 ATOM 4477 C CD . LYS D 4 75 ? 53.583 -24.802 55.222 1.00 97.31 ? 75 LYS D CD 1 ATOM 4478 C CE . LYS D 4 75 ? 54.914 -24.894 55.952 1.00 94.71 ? 75 LYS D CE 1 ATOM 4479 N NZ . LYS D 4 75 ? 55.038 -23.858 57.010 1.00 94.10 ? 75 LYS D NZ 1 ATOM 4480 N N . ASN D 4 76 ? 49.618 -27.375 51.555 1.00 88.85 ? 76 ASN D N 1 ATOM 4481 C CA . ASN D 4 76 ? 48.181 -27.436 51.236 1.00 82.31 ? 76 ASN D CA 1 ATOM 4482 C C . ASN D 4 76 ? 47.427 -26.287 51.910 1.00 80.32 ? 76 ASN D C 1 ATOM 4483 O O . ASN D 4 76 ? 46.345 -26.459 52.481 1.00 79.86 ? 76 ASN D O 1 ATOM 4484 C CB . ASN D 4 76 ? 47.593 -28.828 51.580 1.00 81.43 ? 76 ASN D CB 1 ATOM 4485 C CG . ASN D 4 76 ? 47.223 -29.646 50.346 1.00 83.24 ? 76 ASN D CG 1 ATOM 4486 O OD1 . ASN D 4 76 ? 47.654 -29.366 49.224 1.00 84.73 ? 76 ASN D OD1 1 ATOM 4487 N ND2 . ASN D 4 76 ? 46.415 -30.676 50.559 1.00 84.35 ? 76 ASN D ND2 1 ATOM 4488 N N . GLN D 4 77 ? 48.025 -25.103 51.818 1.00 79.10 ? 77 GLN D N 1 ATOM 4489 C CA . GLN D 4 77 ? 47.509 -23.903 52.457 1.00 78.92 ? 77 GLN D CA 1 ATOM 4490 C C . GLN D 4 77 ? 47.344 -22.800 51.426 1.00 75.44 ? 77 GLN D C 1 ATOM 4491 O O . GLN D 4 77 ? 48.171 -22.651 50.523 1.00 75.38 ? 77 GLN D O 1 ATOM 4492 C CB . GLN D 4 77 ? 48.459 -23.443 53.562 1.00 83.38 ? 77 GLN D CB 1 ATOM 4493 C CG . GLN D 4 77 ? 48.307 -24.220 54.859 1.00 86.41 ? 77 GLN D CG 1 ATOM 4494 C CD . GLN D 4 77 ? 49.340 -23.847 55.907 1.00 88.30 ? 77 GLN D CD 1 ATOM 4495 O OE1 . GLN D 4 77 ? 50.505 -23.588 55.595 1.00 93.66 ? 77 GLN D OE1 1 ATOM 4496 N NE2 . GLN D 4 77 ? 48.918 -23.830 57.164 1.00 89.80 ? 77 GLN D NE2 1 ATOM 4497 N N . VAL D 4 78 ? 46.255 -22.051 51.562 1.00 72.20 ? 78 VAL D N 1 ATOM 4498 C CA . VAL D 4 78 ? 46.011 -20.843 50.782 1.00 70.78 ? 78 VAL D CA 1 ATOM 4499 C C . VAL D 4 78 ? 45.945 -19.714 51.799 1.00 69.20 ? 78 VAL D C 1 ATOM 4500 O O . VAL D 4 78 ? 45.295 -19.852 52.838 1.00 70.33 ? 78 VAL D O 1 ATOM 4501 C CB . VAL D 4 78 ? 44.689 -20.922 49.988 1.00 70.20 ? 78 VAL D CB 1 ATOM 4502 C CG1 . VAL D 4 78 ? 44.543 -19.730 49.049 1.00 68.85 ? 78 VAL D CG1 1 ATOM 4503 C CG2 . VAL D 4 78 ? 44.619 -22.228 49.204 1.00 70.56 ? 78 VAL D CG2 1 ATOM 4504 N N . PHE D 4 79 ? 46.621 -18.610 51.499 1.00 65.60 ? 79 PHE D N 1 ATOM 4505 C CA . PHE D 4 79 ? 46.768 -17.510 52.442 1.00 63.41 ? 79 PHE D CA 1 ATOM 4506 C C . PHE D 4 79 ? 46.016 -16.289 51.951 1.00 62.94 ? 79 PHE D C 1 ATOM 4507 O O . PHE D 4 79 ? 45.748 -16.148 50.764 1.00 65.40 ? 79 PHE D O 1 ATOM 4508 C CB . PHE D 4 79 ? 48.247 -17.184 52.637 1.00 62.02 ? 79 PHE D CB 1 ATOM 4509 C CG . PHE D 4 79 ? 49.093 -18.390 52.939 1.00 61.33 ? 79 PHE D CG 1 ATOM 4510 C CD1 . PHE D 4 79 ? 49.187 -18.883 54.241 1.00 59.70 ? 79 PHE D CD1 1 ATOM 4511 C CD2 . PHE D 4 79 ? 49.777 -19.052 51.919 1.00 60.15 ? 79 PHE D CD2 1 ATOM 4512 C CE1 . PHE D 4 79 ? 49.957 -20.005 54.522 1.00 58.94 ? 79 PHE D CE1 1 ATOM 4513 C CE2 . PHE D 4 79 ? 50.548 -20.175 52.194 1.00 60.28 ? 79 PHE D CE2 1 ATOM 4514 C CZ . PHE D 4 79 ? 50.638 -20.652 53.500 1.00 59.04 ? 79 PHE D CZ 1 ATOM 4515 N N . LEU D 4 80 ? 45.655 -15.426 52.886 1.00 64.16 ? 80 LEU D N 1 ATOM 4516 C CA . LEU D 4 80 ? 45.064 -14.142 52.576 1.00 68.89 ? 80 LEU D CA 1 ATOM 4517 C C . LEU D 4 80 ? 45.773 -13.097 53.418 1.00 72.96 ? 80 LEU D C 1 ATOM 4518 O O . LEU D 4 80 ? 46.157 -13.373 54.556 1.00 72.92 ? 80 LEU D O 1 ATOM 4519 C CB . LEU D 4 80 ? 43.577 -14.151 52.912 1.00 71.26 ? 80 LEU D CB 1 ATOM 4520 C CG . LEU D 4 80 ? 42.767 -12.948 52.416 1.00 72.06 ? 80 LEU D CG 1 ATOM 4521 C CD1 . LEU D 4 80 ? 42.549 -13.042 50.913 1.00 74.24 ? 80 LEU D CD1 1 ATOM 4522 C CD2 . LEU D 4 80 ? 41.438 -12.855 53.151 1.00 72.52 ? 80 LEU D CD2 1 ATOM 4523 N N . LYS D 4 81 ? 45.967 -11.915 52.841 1.00 74.79 ? 81 LYS D N 1 ATOM 4524 C CA . LYS D 4 81 ? 46.443 -10.748 53.572 1.00 76.32 ? 81 LYS D CA 1 ATOM 4525 C C . LYS D 4 81 ? 45.570 -9.579 53.154 1.00 78.50 ? 81 LYS D C 1 ATOM 4526 O O . LYS D 4 81 ? 45.334 -9.389 51.963 1.00 82.45 ? 81 LYS D O 1 ATOM 4527 C CB . LYS D 4 81 ? 47.922 -10.464 53.276 1.00 77.73 ? 81 LYS D CB 1 ATOM 4528 C CG . LYS D 4 81 ? 48.913 -11.107 54.247 1.00 79.94 ? 81 LYS D CG 1 ATOM 4529 C CD . LYS D 4 81 ? 49.425 -12.467 53.778 1.00 82.27 ? 81 LYS D CD 1 ATOM 4530 C CE . LYS D 4 81 ? 50.487 -13.015 54.728 1.00 84.51 ? 81 LYS D CE 1 ATOM 4531 N NZ . LYS D 4 81 ? 51.234 -14.188 54.186 1.00 83.98 ? 81 LYS D NZ 1 ATOM 4532 N N . MET D 4 82 ? 45.086 -8.809 54.127 1.00 79.83 ? 82 MET D N 1 ATOM 4533 C CA . MET D 4 82 ? 44.170 -7.702 53.855 1.00 81.64 ? 82 MET D CA 1 ATOM 4534 C C . MET D 4 82 ? 44.504 -6.484 54.724 1.00 85.05 ? 82 MET D C 1 ATOM 4535 O O . MET D 4 82 ? 44.047 -6.377 55.863 1.00 89.52 ? 82 MET D O 1 ATOM 4536 C CB . MET D 4 82 ? 42.731 -8.164 54.077 1.00 80.53 ? 82 MET D CB 1 ATOM 4537 C CG . MET D 4 82 ? 41.694 -7.230 53.487 1.00 83.02 ? 82 MET D CG 1 ATOM 4538 S SD . MET D 4 82 ? 40.033 -7.648 54.032 1.00 89.91 ? 82 MET D SD 1 ATOM 4539 C CE . MET D 4 82 ? 39.084 -7.129 52.604 1.00 91.13 ? 82 MET D CE 1 ATOM 4540 N N . ASN D 4 83 ? 45.297 -5.566 54.173 1.00 87.33 ? 83 ASN D N 1 ATOM 4541 C CA . ASN D 4 83 ? 45.762 -4.385 54.921 1.00 91.66 ? 83 ASN D CA 1 ATOM 4542 C C . ASN D 4 83 ? 44.703 -3.271 55.030 1.00 93.09 ? 83 ASN D C 1 ATOM 4543 O O . ASN D 4 83 ? 43.643 -3.348 54.408 1.00 91.01 ? 83 ASN D O 1 ATOM 4544 C CB . ASN D 4 83 ? 47.113 -3.865 54.375 1.00 91.85 ? 83 ASN D CB 1 ATOM 4545 C CG . ASN D 4 83 ? 47.032 -3.362 52.945 1.00 91.86 ? 83 ASN D CG 1 ATOM 4546 O OD1 . ASN D 4 83 ? 46.521 -2.273 52.684 1.00 92.91 ? 83 ASN D OD1 1 ATOM 4547 N ND2 . ASN D 4 83 ? 47.570 -4.144 52.014 1.00 91.73 ? 83 ASN D ND2 1 ATOM 4548 N N . SER D 4 84 ? 45.005 -2.264 55.854 1.00 97.17 ? 84 SER D N 1 ATOM 4549 C CA . SER D 4 84 ? 44.138 -1.098 56.107 1.00 99.60 ? 84 SER D CA 1 ATOM 4550 C C . SER D 4 84 ? 42.698 -1.472 56.500 1.00 99.23 ? 84 SER D C 1 ATOM 4551 O O . SER D 4 84 ? 41.735 -1.175 55.785 1.00 96.87 ? 84 SER D O 1 ATOM 4552 C CB . SER D 4 84 ? 44.170 -0.116 54.921 1.00 100.08 ? 84 SER D CB 1 ATOM 4553 O OG . SER D 4 84 ? 43.414 -0.583 53.820 1.00 100.73 ? 84 SER D OG 1 ATOM 4554 N N . LEU D 4 85 ? 42.576 -2.121 57.655 1.00 99.80 ? 85 LEU D N 1 ATOM 4555 C CA . LEU D 4 85 ? 41.285 -2.582 58.171 1.00 101.56 ? 85 LEU D CA 1 ATOM 4556 C C . LEU D 4 85 ? 40.467 -1.448 58.783 1.00 103.77 ? 85 LEU D C 1 ATOM 4557 O O . LEU D 4 85 ? 40.983 -0.360 59.047 1.00 107.73 ? 85 LEU D O 1 ATOM 4558 C CB . LEU D 4 85 ? 41.493 -3.685 59.210 1.00 100.77 ? 85 LEU D CB 1 ATOM 4559 C CG . LEU D 4 85 ? 42.107 -4.972 58.652 1.00 102.03 ? 85 LEU D CG 1 ATOM 4560 C CD1 . LEU D 4 85 ? 42.809 -5.768 59.743 1.00 101.89 ? 85 LEU D CD1 1 ATOM 4561 C CD2 . LEU D 4 85 ? 41.045 -5.816 57.959 1.00 103.12 ? 85 LEU D CD2 1 ATOM 4562 N N . GLN D 4 86 ? 39.185 -1.725 59.003 1.00 104.50 ? 86 GLN D N 1 ATOM 4563 C CA . GLN D 4 86 ? 38.251 -0.765 59.601 1.00 105.64 ? 86 GLN D CA 1 ATOM 4564 C C . GLN D 4 86 ? 37.002 -1.486 60.126 1.00 106.63 ? 86 GLN D C 1 ATOM 4565 O O . GLN D 4 86 ? 36.843 -2.692 59.921 1.00 104.33 ? 86 GLN D O 1 ATOM 4566 C CB . GLN D 4 86 ? 37.876 0.329 58.587 1.00 103.63 ? 86 GLN D CB 1 ATOM 4567 C CG . GLN D 4 86 ? 37.238 -0.178 57.299 1.00 103.11 ? 86 GLN D CG 1 ATOM 4568 C CD . GLN D 4 86 ? 37.214 0.871 56.203 1.00 102.83 ? 86 GLN D CD 1 ATOM 4569 O OE1 . GLN D 4 86 ? 37.088 2.065 56.472 1.00 102.88 ? 86 GLN D OE1 1 ATOM 4570 N NE2 . GLN D 4 86 ? 37.334 0.427 54.956 1.00 99.62 ? 86 GLN D NE2 1 ATOM 4571 N N . THR D 4 87 ? 36.133 -0.747 60.812 1.00 108.36 ? 87 THR D N 1 ATOM 4572 C CA . THR D 4 87 ? 34.925 -1.318 61.422 1.00 109.75 ? 87 THR D CA 1 ATOM 4573 C C . THR D 4 87 ? 33.956 -1.958 60.417 1.00 111.60 ? 87 THR D C 1 ATOM 4574 O O . THR D 4 87 ? 33.300 -2.951 60.741 1.00 113.22 ? 87 THR D O 1 ATOM 4575 C CB . THR D 4 87 ? 34.150 -0.260 62.232 1.00 109.70 ? 87 THR D CB 1 ATOM 4576 O OG1 . THR D 4 87 ? 33.936 0.902 61.419 1.00 107.78 ? 87 THR D OG1 1 ATOM 4577 C CG2 . THR D 4 87 ? 34.920 0.125 63.490 1.00 110.41 ? 87 THR D CG2 1 ATOM 4578 N N . ASP D 4 88 ? 33.883 -1.406 59.203 1.00 109.77 ? 88 ASP D N 1 ATOM 4579 C CA . ASP D 4 88 ? 33.002 -1.942 58.148 1.00 105.70 ? 88 ASP D CA 1 ATOM 4580 C C . ASP D 4 88 ? 33.380 -3.341 57.617 1.00 101.25 ? 88 ASP D C 1 ATOM 4581 O O . ASP D 4 88 ? 32.578 -3.949 56.907 1.00 103.23 ? 88 ASP D O 1 ATOM 4582 C CB . ASP D 4 88 ? 32.900 -0.960 56.968 1.00 106.92 ? 88 ASP D CB 1 ATOM 4583 C CG . ASP D 4 88 ? 32.113 0.295 57.315 1.00 108.66 ? 88 ASP D CG 1 ATOM 4584 O OD1 . ASP D 4 88 ? 32.582 1.083 58.165 1.00 111.81 ? 88 ASP D OD1 1 ATOM 4585 O OD2 . ASP D 4 88 ? 31.028 0.501 56.731 1.00 108.17 ? 88 ASP D OD2 1 ATOM 4586 N N . ASP D 4 89 ? 34.572 -3.845 57.959 1.00 95.37 ? 89 ASP D N 1 ATOM 4587 C CA . ASP D 4 89 ? 35.046 -5.171 57.519 1.00 90.47 ? 89 ASP D CA 1 ATOM 4588 C C . ASP D 4 89 ? 34.897 -6.263 58.602 1.00 85.95 ? 89 ASP D C 1 ATOM 4589 O O . ASP D 4 89 ? 35.733 -7.170 58.713 1.00 79.68 ? 89 ASP D O 1 ATOM 4590 C CB . ASP D 4 89 ? 36.510 -5.061 57.064 1.00 90.30 ? 89 ASP D CB 1 ATOM 4591 C CG . ASP D 4 89 ? 36.735 -3.938 56.047 1.00 89.19 ? 89 ASP D CG 1 ATOM 4592 O OD1 . ASP D 4 89 ? 35.799 -3.579 55.295 1.00 84.99 ? 89 ASP D OD1 1 ATOM 4593 O OD2 . ASP D 4 89 ? 37.865 -3.414 56.000 1.00 90.66 ? 89 ASP D OD2 1 ATOM 4594 N N . THR D 4 90 ? 33.811 -6.182 59.370 1.00 85.43 ? 90 THR D N 1 ATOM 4595 C CA . THR D 4 90 ? 33.544 -7.087 60.486 1.00 85.89 ? 90 THR D CA 1 ATOM 4596 C C . THR D 4 90 ? 32.580 -8.183 60.031 1.00 82.18 ? 90 THR D C 1 ATOM 4597 O O . THR D 4 90 ? 31.452 -7.888 59.630 1.00 79.48 ? 90 THR D O 1 ATOM 4598 C CB . THR D 4 90 ? 32.909 -6.316 61.667 1.00 88.40 ? 90 THR D CB 1 ATOM 4599 O OG1 . THR D 4 90 ? 33.744 -5.205 62.018 1.00 89.93 ? 90 THR D OG1 1 ATOM 4600 C CG2 . THR D 4 90 ? 32.702 -7.220 62.895 1.00 87.38 ? 90 THR D CG2 1 ATOM 4601 N N . GLY D 4 91 ? 33.013 -9.440 60.102 1.00 78.57 ? 91 GLY D N 1 ATOM 4602 C CA . GLY D 4 91 ? 32.158 -10.551 59.685 1.00 75.91 ? 91 GLY D CA 1 ATOM 4603 C C . GLY D 4 91 ? 32.795 -11.924 59.774 1.00 75.21 ? 91 GLY D C 1 ATOM 4604 O O . GLY D 4 91 ? 33.805 -12.110 60.463 1.00 73.65 ? 91 GLY D O 1 ATOM 4605 N N . THR D 4 92 ? 32.180 -12.886 59.079 1.00 74.68 ? 92 THR D N 1 ATOM 4606 C CA . THR D 4 92 ? 32.708 -14.250 58.954 1.00 73.45 ? 92 THR D CA 1 ATOM 4607 C C . THR D 4 92 ? 33.447 -14.381 57.617 1.00 71.25 ? 92 THR D C 1 ATOM 4608 O O . THR D 4 92 ? 33.067 -13.739 56.630 1.00 66.94 ? 92 THR D O 1 ATOM 4609 C CB . THR D 4 92 ? 31.586 -15.311 59.055 1.00 74.62 ? 92 THR D CB 1 ATOM 4610 O OG1 . THR D 4 92 ? 30.725 -15.003 60.160 1.00 75.07 ? 92 THR D OG1 1 ATOM 4611 C CG2 . THR D 4 92 ? 32.173 -16.718 59.250 1.00 74.43 ? 92 THR D CG2 1 ATOM 4612 N N . TYR D 4 93 ? 34.505 -15.197 57.605 1.00 68.45 ? 93 TYR D N 1 ATOM 4613 C CA . TYR D 4 93 ? 35.416 -15.331 56.458 1.00 66.27 ? 93 TYR D CA 1 ATOM 4614 C C . TYR D 4 93 ? 35.609 -16.797 56.068 1.00 64.68 ? 93 TYR D C 1 ATOM 4615 O O . TYR D 4 93 ? 36.192 -17.569 56.837 1.00 60.88 ? 93 TYR D O 1 ATOM 4616 C CB . TYR D 4 93 ? 36.781 -14.696 56.795 1.00 67.24 ? 93 TYR D CB 1 ATOM 4617 C CG . TYR D 4 93 ? 36.804 -13.188 56.641 1.00 65.69 ? 93 TYR D CG 1 ATOM 4618 C CD1 . TYR D 4 93 ? 36.120 -12.365 57.533 1.00 65.36 ? 93 TYR D CD1 1 ATOM 4619 C CD2 . TYR D 4 93 ? 37.497 -12.583 55.595 1.00 65.95 ? 93 TYR D CD2 1 ATOM 4620 C CE1 . TYR D 4 93 ? 36.124 -10.984 57.389 1.00 65.41 ? 93 TYR D CE1 1 ATOM 4621 C CE2 . TYR D 4 93 ? 37.505 -11.202 55.443 1.00 65.93 ? 93 TYR D CE2 1 ATOM 4622 C CZ . TYR D 4 93 ? 36.819 -10.408 56.343 1.00 65.32 ? 93 TYR D CZ 1 ATOM 4623 O OH . TYR D 4 93 ? 36.824 -9.044 56.196 1.00 66.33 ? 93 TYR D OH 1 ATOM 4624 N N . TYR D 4 94 ? 35.136 -17.167 54.870 1.00 66.11 ? 94 TYR D N 1 ATOM 4625 C CA . TYR D 4 94 ? 35.248 -18.547 54.357 1.00 64.63 ? 94 TYR D CA 1 ATOM 4626 C C . TYR D 4 94 ? 36.188 -18.667 53.153 1.00 62.13 ? 94 TYR D C 1 ATOM 4627 O O . TYR D 4 94 ? 36.332 -17.723 52.369 1.00 58.46 ? 94 TYR D O 1 ATOM 4628 C CB . TYR D 4 94 ? 33.884 -19.096 53.926 1.00 63.73 ? 94 TYR D CB 1 ATOM 4629 C CG . TYR D 4 94 ? 32.723 -18.812 54.850 1.00 62.69 ? 94 TYR D CG 1 ATOM 4630 C CD1 . TYR D 4 94 ? 32.000 -17.623 54.735 1.00 61.86 ? 94 TYR D CD1 1 ATOM 4631 C CD2 . TYR D 4 94 ? 32.311 -19.748 55.805 1.00 62.15 ? 94 TYR D CD2 1 ATOM 4632 C CE1 . TYR D 4 94 ? 30.916 -17.359 55.560 1.00 62.12 ? 94 TYR D CE1 1 ATOM 4633 C CE2 . TYR D 4 94 ? 31.227 -19.492 56.638 1.00 62.60 ? 94 TYR D CE2 1 ATOM 4634 C CZ . TYR D 4 94 ? 30.533 -18.296 56.510 1.00 63.31 ? 94 TYR D CZ 1 ATOM 4635 O OH . TYR D 4 94 ? 29.458 -18.020 57.325 1.00 65.34 ? 94 TYR D OH 1 ATOM 4636 N N . CYS D 4 95 ? 36.803 -19.842 53.016 1.00 60.92 ? 95 CYS D N 1 ATOM 4637 C CA . CYS D 4 95 ? 37.490 -20.249 51.794 1.00 65.53 ? 95 CYS D CA 1 ATOM 4638 C C . CYS D 4 95 ? 36.687 -21.395 51.182 1.00 63.26 ? 95 CYS D C 1 ATOM 4639 O O . CYS D 4 95 ? 36.038 -22.153 51.903 1.00 62.44 ? 95 CYS D O 1 ATOM 4640 C CB . CYS D 4 95 ? 38.945 -20.668 52.057 1.00 70.06 ? 95 CYS D CB 1 ATOM 4641 S SG . CYS D 4 95 ? 39.171 -22.151 53.071 1.00 80.41 ? 95 CYS D SG 1 ATOM 4642 N N . THR D 4 96 ? 36.724 -21.500 49.855 1.00 61.39 ? 96 THR D N 1 ATOM 4643 C CA . THR D 4 96 ? 35.867 -22.427 49.106 1.00 59.09 ? 96 THR D CA 1 ATOM 4644 C C . THR D 4 96 ? 36.635 -23.135 48.002 1.00 56.77 ? 96 THR D C 1 ATOM 4645 O O . THR D 4 96 ? 37.574 -22.574 47.455 1.00 57.56 ? 96 THR D O 1 ATOM 4646 C CB . THR D 4 96 ? 34.685 -21.683 48.452 1.00 57.37 ? 96 THR D CB 1 ATOM 4647 O OG1 . THR D 4 96 ? 35.178 -20.607 47.646 1.00 59.72 ? 96 THR D OG1 1 ATOM 4648 C CG2 . THR D 4 96 ? 33.760 -21.122 49.499 1.00 57.13 ? 96 THR D CG2 1 ATOM 4649 N N . ARG D 4 97 ? 36.232 -24.364 47.685 1.00 54.70 ? 97 ARG D N 1 ATOM 4650 C CA . ARG D 4 97 ? 36.764 -25.072 46.529 1.00 54.87 ? 97 ARG D CA 1 ATOM 4651 C C . ARG D 4 97 ? 35.828 -24.847 45.348 1.00 57.15 ? 97 ARG D C 1 ATOM 4652 O O . ARG D 4 97 ? 34.636 -25.169 45.415 1.00 54.24 ? 97 ARG D O 1 ATOM 4653 C CB . ARG D 4 97 ? 36.913 -26.565 46.796 1.00 54.80 ? 97 ARG D CB 1 ATOM 4654 C CG . ARG D 4 97 ? 37.898 -27.216 45.842 1.00 55.89 ? 97 ARG D CG 1 ATOM 4655 C CD . ARG D 4 97 ? 37.887 -28.730 45.923 1.00 56.74 ? 97 ARG D CD 1 ATOM 4656 N NE . ARG D 4 97 ? 36.840 -29.315 45.090 1.00 57.67 ? 97 ARG D NE 1 ATOM 4657 C CZ . ARG D 4 97 ? 36.810 -30.580 44.668 1.00 59.19 ? 97 ARG D CZ 1 ATOM 4658 N NH1 . ARG D 4 97 ? 37.782 -31.441 44.979 1.00 58.17 ? 97 ARG D NH1 1 ATOM 4659 N NH2 . ARG D 4 97 ? 35.794 -30.991 43.911 1.00 60.14 ? 97 ARG D NH2 1 ATOM 4660 N N . ASP D 4 98 ? 36.382 -24.302 44.267 1.00 58.36 ? 98 ASP D N 1 ATOM 4661 C CA . ASP D 4 98 ? 35.604 -23.949 43.091 1.00 58.88 ? 98 ASP D CA 1 ATOM 4662 C C . ASP D 4 98 ? 35.594 -25.083 42.070 1.00 57.00 ? 98 ASP D C 1 ATOM 4663 O O . ASP D 4 98 ? 36.621 -25.714 41.821 1.00 57.38 ? 98 ASP D O 1 ATOM 4664 C CB . ASP D 4 98 ? 36.156 -22.665 42.460 1.00 61.72 ? 98 ASP D CB 1 ATOM 4665 C CG . ASP D 4 98 ? 35.992 -21.439 43.360 1.00 64.53 ? 98 ASP D CG 1 ATOM 4666 O OD1 . ASP D 4 98 ? 35.531 -21.585 44.519 1.00 65.72 ? 98 ASP D OD1 1 ATOM 4667 O OD2 . ASP D 4 98 ? 36.328 -20.324 42.898 1.00 63.88 ? 98 ASP D OD2 1 ATOM 4668 N N . GLU D 4 99 ? 34.418 -25.341 41.504 1.00 56.57 ? 99 GLU D N 1 ATOM 4669 C CA . GLU D 4 99 ? 34.257 -26.251 40.374 1.00 59.09 ? 99 GLU D CA 1 ATOM 4670 C C . GLU D 4 99 ? 34.107 -25.367 39.132 1.00 59.18 ? 99 GLU D C 1 ATOM 4671 O O . GLU D 4 99 ? 33.822 -24.174 39.267 1.00 59.17 ? 99 GLU D O 1 ATOM 4672 C CB . GLU D 4 99 ? 33.019 -27.140 40.571 1.00 59.11 ? 99 GLU D CB 1 ATOM 4673 C CG . GLU D 4 99 ? 33.214 -28.607 40.190 1.00 60.55 ? 99 GLU D CG 1 ATOM 4674 C CD . GLU D 4 99 ? 33.924 -29.440 41.260 1.00 61.66 ? 99 GLU D CD 1 ATOM 4675 O OE1 . GLU D 4 99 ? 33.852 -29.108 42.466 1.00 58.03 ? 99 GLU D OE1 1 ATOM 4676 O OE2 . GLU D 4 99 ? 34.550 -30.459 40.891 1.00 63.69 ? 99 GLU D OE2 1 ATOM 4677 N N . ARG D 4 100 ? 34.290 -25.940 37.936 1.00 59.86 ? 100 ARG D N 1 ATOM 4678 C CA . ARG D 4 100 ? 34.155 -25.178 36.671 1.00 59.35 ? 100 ARG D CA 1 ATOM 4679 C C . ARG D 4 100 ? 33.473 -25.915 35.521 1.00 54.55 ? 100 ARG D C 1 ATOM 4680 O O . ARG D 4 100 ? 33.376 -27.135 35.504 1.00 56.57 ? 100 ARG D O 1 ATOM 4681 C CB . ARG D 4 100 ? 35.519 -24.645 36.191 1.00 62.37 ? 100 ARG D CB 1 ATOM 4682 C CG . ARG D 4 100 ? 36.628 -25.681 36.050 1.00 64.98 ? 100 ARG D CG 1 ATOM 4683 C CD . ARG D 4 100 ? 36.744 -26.284 34.658 1.00 65.96 ? 100 ARG D CD 1 ATOM 4684 N NE . ARG D 4 100 ? 37.407 -25.381 33.707 1.00 67.44 ? 100 ARG D NE 1 ATOM 4685 C CZ . ARG D 4 100 ? 38.314 -25.738 32.784 1.00 67.23 ? 100 ARG D CZ 1 ATOM 4686 N NH1 . ARG D 4 100 ? 38.735 -27.001 32.655 1.00 68.70 ? 100 ARG D NH1 1 ATOM 4687 N NH2 . ARG D 4 100 ? 38.827 -24.810 31.979 1.00 65.19 ? 100 ARG D NH2 1 ATOM 4688 N N . ILE D 4 101 ? 32.992 -25.129 34.568 1.00 50.77 ? 101 ILE D N 1 ATOM 4689 C CA . ILE D 4 101 ? 32.547 -25.622 33.269 1.00 47.46 ? 101 ILE D CA 1 ATOM 4690 C C . ILE D 4 101 ? 33.088 -24.622 32.242 1.00 45.31 ? 101 ILE D C 1 ATOM 4691 O O . ILE D 4 101 ? 32.763 -23.435 32.294 1.00 43.84 ? 101 ILE D O 1 ATOM 4692 C CB . ILE D 4 101 ? 31.000 -25.781 33.186 1.00 46.51 ? 101 ILE D CB 1 ATOM 4693 C CG1 . ILE D 4 101 ? 30.564 -26.321 31.816 1.00 46.09 ? 101 ILE D CG1 1 ATOM 4694 C CG2 . ILE D 4 101 ? 30.258 -24.472 33.458 1.00 46.14 ? 101 ILE D CG2 1 ATOM 4695 C CD1 . ILE D 4 101 ? 31.068 -27.711 31.523 1.00 46.77 ? 101 ILE D CD1 1 ATOM 4696 N N . ARG D 4 102 ? 33.938 -25.102 31.337 1.00 43.30 ? 102 ARG D N 1 ATOM 4697 C CA . ARG D 4 102 ? 34.604 -24.249 30.360 1.00 41.81 ? 102 ARG D CA 1 ATOM 4698 C C . ARG D 4 102 ? 35.300 -23.080 31.085 1.00 41.99 ? 102 ARG D C 1 ATOM 4699 O O . ARG D 4 102 ? 36.185 -23.341 31.895 1.00 43.46 ? 102 ARG D O 1 ATOM 4700 C CB . ARG D 4 102 ? 33.617 -23.822 29.258 1.00 40.82 ? 102 ARG D CB 1 ATOM 4701 C CG . ARG D 4 102 ? 32.895 -24.973 28.565 1.00 40.37 ? 102 ARG D CG 1 ATOM 4702 C CD . ARG D 4 102 ? 33.825 -26.096 28.117 1.00 40.50 ? 102 ARG D CD 1 ATOM 4703 N NE . ARG D 4 102 ? 33.124 -27.103 27.312 1.00 40.93 ? 102 ARG D NE 1 ATOM 4704 C CZ . ARG D 4 102 ? 32.877 -27.022 26.002 1.00 40.66 ? 102 ARG D CZ 1 ATOM 4705 N NH1 . ARG D 4 102 ? 33.277 -25.977 25.278 1.00 42.44 ? 102 ARG D NH1 1 ATOM 4706 N NH2 . ARG D 4 102 ? 32.228 -28.010 25.394 1.00 39.75 ? 102 ARG D NH2 1 ATOM 4707 N N . ALA D 4 103 ? 34.905 -21.827 30.838 1.00 41.45 ? 103 ALA D N 1 ATOM 4708 C CA . ALA D 4 103 ? 35.516 -20.663 31.500 1.00 42.01 ? 103 ALA D CA 1 ATOM 4709 C C . ALA D 4 103 ? 34.738 -20.152 32.716 1.00 42.61 ? 103 ALA D C 1 ATOM 4710 O O . ALA D 4 103 ? 35.197 -19.226 33.387 1.00 46.27 ? 103 ALA D O 1 ATOM 4711 C CB . ALA D 4 103 ? 35.691 -19.532 30.499 1.00 42.42 ? 103 ALA D CB 1 ATOM 4712 N N . ILE D 4 104 ? 33.578 -20.745 32.992 1.00 42.26 ? 104 ILE D N 1 ATOM 4713 C CA . ILE D 4 104 ? 32.701 -20.332 34.089 1.00 42.33 ? 104 ILE D CA 1 ATOM 4714 C C . ILE D 4 104 ? 33.124 -21.053 35.373 1.00 43.22 ? 104 ILE D C 1 ATOM 4715 O O . ILE D 4 104 ? 33.608 -22.184 35.321 1.00 44.11 ? 104 ILE D O 1 ATOM 4716 C CB . ILE D 4 104 ? 31.224 -20.679 33.770 1.00 42.54 ? 104 ILE D CB 1 ATOM 4717 C CG1 . ILE D 4 104 ? 30.774 -20.036 32.449 1.00 42.68 ? 104 ILE D CG1 1 ATOM 4718 C CG2 . ILE D 4 104 ? 30.287 -20.259 34.901 1.00 43.28 ? 104 ILE D CG2 1 ATOM 4719 C CD1 . ILE D 4 104 ? 30.678 -18.525 32.474 1.00 44.01 ? 104 ILE D CD1 1 ATOM 4720 N N . ASN D 4 105 ? 32.943 -20.389 36.516 1.00 43.76 ? 105 ASN D N 1 ATOM 4721 C CA . ASN D 4 105 ? 33.265 -20.961 37.834 1.00 44.73 ? 105 ASN D CA 1 ATOM 4722 C C . ASN D 4 105 ? 32.114 -20.789 38.835 1.00 44.58 ? 105 ASN D C 1 ATOM 4723 O O . ASN D 4 105 ? 31.294 -19.875 38.715 1.00 45.07 ? 105 ASN D O 1 ATOM 4724 C CB . ASN D 4 105 ? 34.525 -20.304 38.396 1.00 45.06 ? 105 ASN D CB 1 ATOM 4725 C CG . ASN D 4 105 ? 35.650 -20.259 37.390 1.00 45.30 ? 105 ASN D CG 1 ATOM 4726 O OD1 . ASN D 4 105 ? 36.128 -21.293 36.943 1.00 45.88 ? 105 ASN D OD1 1 ATOM 4727 N ND2 . ASN D 4 105 ? 36.062 -19.057 37.013 1.00 46.50 ? 105 ASN D ND2 1 ATOM 4728 N N . TRP D 4 106 ? 32.062 -21.684 39.815 1.00 43.57 ? 106 TRP D N 1 ATOM 4729 C CA . TRP D 4 106 ? 31.135 -21.556 40.936 1.00 44.42 ? 106 TRP D CA 1 ATOM 4730 C C . TRP D 4 106 ? 31.741 -22.168 42.202 1.00 45.66 ? 106 TRP D C 1 ATOM 4731 O O . TRP D 4 106 ? 32.765 -22.850 42.135 1.00 44.32 ? 106 TRP D O 1 ATOM 4732 C CB . TRP D 4 106 ? 29.769 -22.160 40.589 1.00 44.00 ? 106 TRP D CB 1 ATOM 4733 C CG . TRP D 4 106 ? 29.712 -23.655 40.493 1.00 43.76 ? 106 TRP D CG 1 ATOM 4734 C CD1 . TRP D 4 106 ? 29.367 -24.515 41.481 1.00 44.83 ? 106 TRP D CD1 1 ATOM 4735 C CD2 . TRP D 4 106 ? 29.968 -24.458 39.337 1.00 44.85 ? 106 TRP D CD2 1 ATOM 4736 N NE1 . TRP D 4 106 ? 29.397 -25.806 41.026 1.00 45.42 ? 106 TRP D NE1 1 ATOM 4737 C CE2 . TRP D 4 106 ? 29.764 -25.802 39.710 1.00 45.01 ? 106 TRP D CE2 1 ATOM 4738 C CE3 . TRP D 4 106 ? 30.354 -24.174 38.020 1.00 45.94 ? 106 TRP D CE3 1 ATOM 4739 C CZ2 . TRP D 4 106 ? 29.940 -26.869 38.817 1.00 45.09 ? 106 TRP D CZ2 1 ATOM 4740 C CZ3 . TRP D 4 106 ? 30.530 -25.237 37.130 1.00 44.89 ? 106 TRP D CZ3 1 ATOM 4741 C CH2 . TRP D 4 106 ? 30.323 -26.566 37.537 1.00 44.62 ? 106 TRP D CH2 1 ATOM 4742 N N . PHE D 4 107 ? 31.116 -21.899 43.348 1.00 47.41 ? 107 PHE D N 1 ATOM 4743 C CA . PHE D 4 107 ? 31.650 -22.321 44.652 1.00 48.31 ? 107 PHE D CA 1 ATOM 4744 C C . PHE D 4 107 ? 31.025 -23.654 45.036 1.00 50.30 ? 107 PHE D C 1 ATOM 4745 O O . PHE D 4 107 ? 29.816 -23.734 45.230 1.00 51.81 ? 107 PHE D O 1 ATOM 4746 C CB . PHE D 4 107 ? 31.367 -21.263 45.721 1.00 46.51 ? 107 PHE D CB 1 ATOM 4747 C CG . PHE D 4 107 ? 31.676 -19.867 45.272 1.00 45.72 ? 107 PHE D CG 1 ATOM 4748 C CD1 . PHE D 4 107 ? 32.976 -19.503 44.972 1.00 45.04 ? 107 PHE D CD1 1 ATOM 4749 C CD2 . PHE D 4 107 ? 30.663 -18.924 45.124 1.00 46.13 ? 107 PHE D CD2 1 ATOM 4750 C CE1 . PHE D 4 107 ? 33.273 -18.222 44.546 1.00 45.56 ? 107 PHE D CE1 1 ATOM 4751 C CE2 . PHE D 4 107 ? 30.950 -17.634 44.702 1.00 46.04 ? 107 PHE D CE2 1 ATOM 4752 C CZ . PHE D 4 107 ? 32.259 -17.284 44.410 1.00 45.93 ? 107 PHE D CZ 1 ATOM 4753 N N . ALA D 4 108 ? 31.843 -24.698 45.131 1.00 52.99 ? 108 ALA D N 1 ATOM 4754 C CA . ALA D 4 108 ? 31.343 -26.053 45.379 1.00 55.29 ? 108 ALA D CA 1 ATOM 4755 C C . ALA D 4 108 ? 31.336 -26.390 46.865 1.00 55.85 ? 108 ALA D C 1 ATOM 4756 O O . ALA D 4 108 ? 30.313 -26.809 47.399 1.00 57.26 ? 108 ALA D O 1 ATOM 4757 C CB . ALA D 4 108 ? 32.171 -27.071 44.606 1.00 56.99 ? 108 ALA D CB 1 ATOM 4758 N N . TYR D 4 109 ? 32.480 -26.199 47.520 1.00 56.71 ? 109 TYR D N 1 ATOM 4759 C CA . TYR D 4 109 ? 32.669 -26.583 48.919 1.00 56.84 ? 109 TYR D CA 1 ATOM 4760 C C . TYR D 4 109 ? 33.041 -25.398 49.785 1.00 56.16 ? 109 TYR D C 1 ATOM 4761 O O . TYR D 4 109 ? 33.418 -24.350 49.275 1.00 56.43 ? 109 TYR D O 1 ATOM 4762 C CB . TYR D 4 109 ? 33.727 -27.675 49.007 1.00 56.70 ? 109 TYR D CB 1 ATOM 4763 C CG . TYR D 4 109 ? 33.254 -28.962 48.372 1.00 58.57 ? 109 TYR D CG 1 ATOM 4764 C CD1 . TYR D 4 109 ? 32.433 -29.844 49.078 1.00 59.93 ? 109 TYR D CD1 1 ATOM 4765 C CD2 . TYR D 4 109 ? 33.593 -29.288 47.057 1.00 58.89 ? 109 TYR D CD2 1 ATOM 4766 C CE1 . TYR D 4 109 ? 31.982 -31.024 48.504 1.00 60.40 ? 109 TYR D CE1 1 ATOM 4767 C CE2 . TYR D 4 109 ? 33.150 -30.468 46.473 1.00 59.95 ? 109 TYR D CE2 1 ATOM 4768 C CZ . TYR D 4 109 ? 32.342 -31.332 47.202 1.00 61.36 ? 109 TYR D CZ 1 ATOM 4769 O OH . TYR D 4 109 ? 31.892 -32.505 46.644 1.00 62.73 ? 109 TYR D OH 1 ATOM 4770 N N . TRP D 4 110 ? 32.885 -25.570 51.094 1.00 55.80 ? 110 TRP D N 1 ATOM 4771 C CA . TRP D 4 110 ? 33.166 -24.529 52.090 1.00 56.19 ? 110 TRP D CA 1 ATOM 4772 C C . TRP D 4 110 ? 33.876 -25.130 53.305 1.00 59.05 ? 110 TRP D C 1 ATOM 4773 O O . TRP D 4 110 ? 33.837 -26.345 53.538 1.00 60.84 ? 110 TRP D O 1 ATOM 4774 C CB . TRP D 4 110 ? 31.864 -23.892 52.580 1.00 54.31 ? 110 TRP D CB 1 ATOM 4775 C CG . TRP D 4 110 ? 31.299 -22.770 51.756 1.00 52.14 ? 110 TRP D CG 1 ATOM 4776 C CD1 . TRP D 4 110 ? 31.412 -21.435 52.013 1.00 52.33 ? 110 TRP D CD1 1 ATOM 4777 C CD2 . TRP D 4 110 ? 30.476 -22.883 50.586 1.00 51.05 ? 110 TRP D CD2 1 ATOM 4778 N NE1 . TRP D 4 110 ? 30.735 -20.705 51.065 1.00 51.70 ? 110 TRP D NE1 1 ATOM 4779 C CE2 . TRP D 4 110 ? 30.150 -21.566 50.176 1.00 50.60 ? 110 TRP D CE2 1 ATOM 4780 C CE3 . TRP D 4 110 ? 29.992 -23.967 49.835 1.00 51.37 ? 110 TRP D CE3 1 ATOM 4781 C CZ2 . TRP D 4 110 ? 29.360 -21.300 49.049 1.00 51.32 ? 110 TRP D CZ2 1 ATOM 4782 C CZ3 . TRP D 4 110 ? 29.201 -23.703 48.708 1.00 51.25 ? 110 TRP D CZ3 1 ATOM 4783 C CH2 . TRP D 4 110 ? 28.894 -22.376 48.330 1.00 51.27 ? 110 TRP D CH2 1 ATOM 4784 N N . GLY D 4 111 ? 34.521 -24.260 54.072 1.00 61.14 ? 111 GLY D N 1 ATOM 4785 C CA . GLY D 4 111 ? 34.972 -24.591 55.415 1.00 64.95 ? 111 GLY D CA 1 ATOM 4786 C C . GLY D 4 111 ? 34.005 -23.975 56.410 1.00 70.30 ? 111 GLY D C 1 ATOM 4787 O O . GLY D 4 111 ? 33.127 -23.185 56.024 1.00 68.51 ? 111 GLY D O 1 ATOM 4788 N N . GLN D 4 112 ? 34.164 -24.349 57.684 1.00 74.33 ? 112 GLN D N 1 ATOM 4789 C CA . GLN D 4 112 ? 33.300 -23.875 58.781 1.00 77.50 ? 112 GLN D CA 1 ATOM 4790 C C . GLN D 4 112 ? 33.205 -22.346 58.822 1.00 77.61 ? 112 GLN D C 1 ATOM 4791 O O . GLN D 4 112 ? 32.112 -21.788 58.949 1.00 75.21 ? 112 GLN D O 1 ATOM 4792 C CB . GLN D 4 112 ? 33.830 -24.380 60.128 1.00 82.31 ? 112 GLN D CB 1 ATOM 4793 C CG . GLN D 4 112 ? 32.926 -24.076 61.330 1.00 86.15 ? 112 GLN D CG 1 ATOM 4794 C CD . GLN D 4 112 ? 33.671 -23.651 62.594 1.00 88.26 ? 112 GLN D CD 1 ATOM 4795 O OE1 . GLN D 4 112 ? 34.903 -23.546 62.618 1.00 90.03 ? 112 GLN D OE1 1 ATOM 4796 N NE2 . GLN D 4 112 ? 32.912 -23.391 63.657 1.00 87.87 ? 112 GLN D NE2 1 ATOM 4797 N N . GLY D 4 113 ? 34.359 -21.691 58.732 1.00 77.72 ? 113 GLY D N 1 ATOM 4798 C CA . GLY D 4 113 ? 34.446 -20.234 58.701 1.00 78.23 ? 113 GLY D CA 1 ATOM 4799 C C . GLY D 4 113 ? 35.408 -19.724 59.751 1.00 79.88 ? 113 GLY D C 1 ATOM 4800 O O . GLY D 4 113 ? 36.127 -20.503 60.383 1.00 75.84 ? 113 GLY D O 1 ATOM 4801 N N . THR D 4 114 ? 35.435 -18.402 59.898 1.00 83.74 ? 114 THR D N 1 ATOM 4802 C CA . THR D 4 114 ? 36.178 -17.715 60.959 1.00 85.27 ? 114 THR D CA 1 ATOM 4803 C C . THR D 4 114 ? 35.565 -16.339 61.172 1.00 89.11 ? 114 THR D C 1 ATOM 4804 O O . THR D 4 114 ? 35.454 -15.556 60.222 1.00 87.09 ? 114 THR D O 1 ATOM 4805 C CB . THR D 4 114 ? 37.669 -17.504 60.616 1.00 84.20 ? 114 THR D CB 1 ATOM 4806 O OG1 . THR D 4 114 ? 38.281 -18.756 60.302 1.00 85.09 ? 114 THR D OG1 1 ATOM 4807 C CG2 . THR D 4 114 ? 38.420 -16.860 61.796 1.00 85.11 ? 114 THR D CG2 1 ATOM 4808 N N . LEU D 4 115 ? 35.176 -16.045 62.411 1.00 93.36 ? 115 LEU D N 1 ATOM 4809 C CA . LEU D 4 115 ? 34.674 -14.720 62.757 1.00 95.49 ? 115 LEU D CA 1 ATOM 4810 C C . LEU D 4 115 ? 35.862 -13.769 62.912 1.00 93.33 ? 115 LEU D C 1 ATOM 4811 O O . LEU D 4 115 ? 36.866 -14.112 63.543 1.00 88.51 ? 115 LEU D O 1 ATOM 4812 C CB . LEU D 4 115 ? 33.837 -14.765 64.042 1.00 98.54 ? 115 LEU D CB 1 ATOM 4813 C CG . LEU D 4 115 ? 32.892 -13.578 64.277 1.00 101.53 ? 115 LEU D CG 1 ATOM 4814 C CD1 . LEU D 4 115 ? 31.782 -13.522 63.231 1.00 101.28 ? 115 LEU D CD1 1 ATOM 4815 C CD2 . LEU D 4 115 ? 32.303 -13.642 65.679 1.00 102.32 ? 115 LEU D CD2 1 ATOM 4816 N N . VAL D 4 116 ? 35.745 -12.592 62.301 1.00 93.47 ? 116 VAL D N 1 ATOM 4817 C CA . VAL D 4 116 ? 36.782 -11.569 62.339 1.00 95.09 ? 116 VAL D CA 1 ATOM 4818 C C . VAL D 4 116 ? 36.112 -10.230 62.631 1.00 96.30 ? 116 VAL D C 1 ATOM 4819 O O . VAL D 4 116 ? 35.253 -9.777 61.868 1.00 90.43 ? 116 VAL D O 1 ATOM 4820 C CB . VAL D 4 116 ? 37.569 -11.511 61.009 1.00 97.46 ? 116 VAL D CB 1 ATOM 4821 C CG1 . VAL D 4 116 ? 38.495 -10.296 60.964 1.00 98.84 ? 116 VAL D CG1 1 ATOM 4822 C CG2 . VAL D 4 116 ? 38.360 -12.801 60.808 1.00 96.34 ? 116 VAL D CG2 1 ATOM 4823 N N . THR D 4 117 ? 36.535 -9.605 63.729 1.00 101.16 ? 117 THR D N 1 ATOM 4824 C CA . THR D 4 117 ? 35.922 -8.378 64.236 1.00 102.40 ? 117 THR D CA 1 ATOM 4825 C C . THR D 4 117 ? 36.994 -7.296 64.427 1.00 101.99 ? 117 THR D C 1 ATOM 4826 O O . THR D 4 117 ? 38.099 -7.580 64.902 1.00 97.22 ? 117 THR D O 1 ATOM 4827 C CB . THR D 4 117 ? 35.110 -8.652 65.531 1.00 104.51 ? 117 THR D CB 1 ATOM 4828 O OG1 . THR D 4 117 ? 34.709 -7.417 66.136 1.00 106.57 ? 117 THR D OG1 1 ATOM 4829 C CG2 . THR D 4 117 ? 35.906 -9.485 66.541 1.00 104.87 ? 117 THR D CG2 1 ATOM 4830 N N . VAL D 4 118 ? 36.649 -6.065 64.040 1.00 106.20 ? 118 VAL D N 1 ATOM 4831 C CA . VAL D 4 118 ? 37.599 -4.947 63.947 1.00 109.58 ? 118 VAL D CA 1 ATOM 4832 C C . VAL D 4 118 ? 37.281 -3.850 64.975 1.00 108.65 ? 118 VAL D C 1 ATOM 4833 O O . VAL D 4 118 ? 36.464 -2.955 64.715 1.00 104.81 ? 118 VAL D O 1 ATOM 4834 C CB . VAL D 4 118 ? 37.622 -4.343 62.518 1.00 111.96 ? 118 VAL D CB 1 ATOM 4835 C CG1 . VAL D 4 118 ? 38.647 -3.215 62.421 1.00 113.33 ? 118 VAL D CG1 1 ATOM 4836 C CG2 . VAL D 4 118 ? 37.912 -5.425 61.483 1.00 114.21 ? 118 VAL D CG2 1 ATOM 4837 N N . SER D 4 119 ? 37.941 -3.937 66.133 1.00 107.75 ? 119 SER D N 1 ATOM 4838 C CA . SER D 4 119 ? 37.826 -2.940 67.206 1.00 105.37 ? 119 SER D CA 1 ATOM 4839 C C . SER D 4 119 ? 39.127 -2.837 68.002 1.00 105.09 ? 119 SER D C 1 ATOM 4840 O O . SER D 4 119 ? 39.875 -3.814 68.124 1.00 102.28 ? 119 SER D O 1 ATOM 4841 C CB . SER D 4 119 ? 36.671 -3.293 68.149 1.00 104.14 ? 119 SER D CB 1 ATOM 4842 O OG . SER D 4 119 ? 36.485 -2.297 69.143 1.00 100.68 ? 119 SER D OG 1 ATOM 4843 N N . SER D 4 120 ? 39.371 -1.649 68.553 1.00 105.45 ? 120 SER D N 1 ATOM 4844 C CA . SER D 4 120 ? 40.604 -1.356 69.293 1.00 104.03 ? 120 SER D CA 1 ATOM 4845 C C . SER D 4 120 ? 40.705 -2.056 70.653 1.00 104.50 ? 120 SER D C 1 ATOM 4846 O O . SER D 4 120 ? 41.812 -2.227 71.169 1.00 106.06 ? 120 SER D O 1 ATOM 4847 C CB . SER D 4 120 ? 40.748 0.155 69.496 1.00 100.36 ? 120 SER D CB 1 ATOM 4848 O OG . SER D 4 120 ? 40.736 0.838 68.255 1.00 96.93 ? 120 SER D OG 1 ATOM 4849 N N . ALA D 4 121 ? 39.562 -2.458 71.218 1.00 102.76 ? 121 ALA D N 1 ATOM 4850 C CA . ALA D 4 121 ? 39.490 -3.040 72.567 1.00 102.04 ? 121 ALA D CA 1 ATOM 4851 C C . ALA D 4 121 ? 40.431 -4.225 72.803 1.00 100.88 ? 121 ALA D C 1 ATOM 4852 O O . ALA D 4 121 ? 40.747 -4.975 71.883 1.00 98.21 ? 121 ALA D O 1 ATOM 4853 C CB . ALA D 4 121 ? 38.057 -3.447 72.881 1.00 102.41 ? 121 ALA D CB 1 ATOM 4854 N N . GLU D 4 122 ? 40.864 -4.376 74.053 1.00 104.74 ? 122 GLU D N 1 ATOM 4855 C CA . GLU D 4 122 ? 41.821 -5.413 74.443 1.00 107.99 ? 122 GLU D CA 1 ATOM 4856 C C . GLU D 4 122 ? 41.115 -6.768 74.528 1.00 107.90 ? 122 GLU D C 1 ATOM 4857 O O . GLU D 4 122 ? 39.935 -6.836 74.877 1.00 108.43 ? 122 GLU D O 1 ATOM 4858 C CB . GLU D 4 122 ? 42.469 -5.060 75.795 1.00 110.35 ? 122 GLU D CB 1 ATOM 4859 C CG . GLU D 4 122 ? 43.779 -5.787 76.108 1.00 114.06 ? 122 GLU D CG 1 ATOM 4860 C CD . GLU D 4 122 ? 45.016 -5.163 75.462 1.00 117.00 ? 122 GLU D CD 1 ATOM 4861 O OE1 . GLU D 4 122 ? 44.884 -4.387 74.491 1.00 119.11 ? 122 GLU D OE1 1 ATOM 4862 O OE2 . GLU D 4 122 ? 46.138 -5.461 75.928 1.00 117.52 ? 122 GLU D OE2 1 ATOM 4863 N N . THR D 4 123 ? 41.842 -7.836 74.200 1.00 109.15 ? 123 THR D N 1 ATOM 4864 C CA . THR D 4 123 ? 41.326 -9.203 74.320 1.00 107.54 ? 123 THR D CA 1 ATOM 4865 C C . THR D 4 123 ? 41.174 -9.558 75.796 1.00 103.54 ? 123 THR D C 1 ATOM 4866 O O . THR D 4 123 ? 42.169 -9.686 76.513 1.00 98.22 ? 123 THR D O 1 ATOM 4867 C CB . THR D 4 123 ? 42.258 -10.239 73.656 1.00 108.42 ? 123 THR D CB 1 ATOM 4868 O OG1 . THR D 4 123 ? 43.578 -10.128 74.205 1.00 111.30 ? 123 THR D OG1 1 ATOM 4869 C CG2 . THR D 4 123 ? 42.318 -10.033 72.152 1.00 106.98 ? 123 THR D CG2 1 ATOM 4870 N N . THR D 4 124 ? 39.927 -9.716 76.236 1.00 102.90 ? 124 THR D N 1 ATOM 4871 C CA . THR D 4 124 ? 39.619 -9.892 77.651 1.00 104.68 ? 124 THR D CA 1 ATOM 4872 C C . THR D 4 124 ? 39.529 -11.377 78.003 1.00 107.15 ? 124 THR D C 1 ATOM 4873 O O . THR D 4 124 ? 39.045 -12.190 77.204 1.00 100.63 ? 124 THR D O 1 ATOM 4874 C CB . THR D 4 124 ? 38.302 -9.185 78.028 1.00 103.10 ? 124 THR D CB 1 ATOM 4875 O OG1 . THR D 4 124 ? 38.210 -7.933 77.334 1.00 99.30 ? 124 THR D OG1 1 ATOM 4876 C CG2 . THR D 4 124 ? 38.234 -8.938 79.536 1.00 102.07 ? 124 THR D CG2 1 ATOM 4877 N N . ALA D 4 125 ? 40.000 -11.712 79.206 1.00 110.62 ? 125 ALA D N 1 ATOM 4878 C CA . ALA D 4 125 ? 40.023 -13.091 79.695 1.00 113.89 ? 125 ALA D CA 1 ATOM 4879 C C . ALA D 4 125 ? 38.646 -13.474 80.244 1.00 113.67 ? 125 ALA D C 1 ATOM 4880 O O . ALA D 4 125 ? 38.090 -12.727 81.052 1.00 116.45 ? 125 ALA D O 1 ATOM 4881 C CB . ALA D 4 125 ? 41.078 -13.246 80.782 1.00 113.53 ? 125 ALA D CB 1 ATOM 4882 N N . PRO D 4 126 ? 38.093 -14.637 79.827 1.00 110.41 ? 126 PRO D N 1 ATOM 4883 C CA . PRO D 4 126 ? 36.783 -15.058 80.353 1.00 108.00 ? 126 PRO D CA 1 ATOM 4884 C C . PRO D 4 126 ? 36.795 -15.415 81.841 1.00 104.02 ? 126 PRO D C 1 ATOM 4885 O O . PRO D 4 126 ? 37.859 -15.512 82.452 1.00 106.45 ? 126 PRO D O 1 ATOM 4886 C CB . PRO D 4 126 ? 36.435 -16.298 79.515 1.00 109.42 ? 126 PRO D CB 1 ATOM 4887 C CG . PRO D 4 126 ? 37.731 -16.785 78.976 1.00 111.86 ? 126 PRO D CG 1 ATOM 4888 C CD . PRO D 4 126 ? 38.615 -15.586 78.825 1.00 111.55 ? 126 PRO D CD 1 ATOM 4889 N N . SER D 4 127 ? 35.603 -15.581 82.406 1.00 100.60 ? 127 SER D N 1 ATOM 4890 C CA . SER D 4 127 ? 35.432 -16.074 83.769 1.00 99.94 ? 127 SER D CA 1 ATOM 4891 C C . SER D 4 127 ? 34.371 -17.159 83.730 1.00 104.26 ? 127 SER D C 1 ATOM 4892 O O . SER D 4 127 ? 33.235 -16.892 83.333 1.00 105.97 ? 127 SER D O 1 ATOM 4893 C CB . SER D 4 127 ? 34.998 -14.952 84.706 1.00 96.63 ? 127 SER D CB 1 ATOM 4894 O OG . SER D 4 127 ? 35.910 -13.876 84.649 1.00 95.06 ? 127 SER D OG 1 ATOM 4895 N N . VAL D 4 128 ? 34.750 -18.375 84.118 1.00 106.21 ? 128 VAL D N 1 ATOM 4896 C CA . VAL D 4 128 ? 33.841 -19.518 84.121 1.00 104.53 ? 128 VAL D CA 1 ATOM 4897 C C . VAL D 4 128 ? 33.509 -19.878 85.569 1.00 103.66 ? 128 VAL D C 1 ATOM 4898 O O . VAL D 4 128 ? 34.318 -20.499 86.264 1.00 99.29 ? 128 VAL D O 1 ATOM 4899 C CB . VAL D 4 128 ? 34.439 -20.723 83.358 1.00 104.30 ? 128 VAL D CB 1 ATOM 4900 C CG1 . VAL D 4 128 ? 33.481 -21.914 83.375 1.00 105.35 ? 128 VAL D CG1 1 ATOM 4901 C CG2 . VAL D 4 128 ? 34.770 -20.319 81.925 1.00 102.03 ? 128 VAL D CG2 1 ATOM 4902 N N . TYR D 4 129 ? 32.324 -19.452 86.012 1.00 105.02 ? 129 TYR D N 1 ATOM 4903 C CA . TYR D 4 129 ? 31.786 -19.798 87.329 1.00 105.50 ? 129 TYR D CA 1 ATOM 4904 C C . TYR D 4 129 ? 30.857 -21.019 87.205 1.00 106.14 ? 129 TYR D C 1 ATOM 4905 O O . TYR D 4 129 ? 30.248 -21.219 86.149 1.00 103.52 ? 129 TYR D O 1 ATOM 4906 C CB . TYR D 4 129 ? 31.001 -18.622 87.911 1.00 105.03 ? 129 TYR D CB 1 ATOM 4907 C CG . TYR D 4 129 ? 31.767 -17.316 87.984 1.00 103.77 ? 129 TYR D CG 1 ATOM 4908 C CD1 . TYR D 4 129 ? 32.741 -17.110 88.955 1.00 102.74 ? 129 TYR D CD1 1 ATOM 4909 C CD2 . TYR D 4 129 ? 31.500 -16.274 87.094 1.00 104.58 ? 129 TYR D CD2 1 ATOM 4910 C CE1 . TYR D 4 129 ? 33.438 -15.911 89.033 1.00 102.43 ? 129 TYR D CE1 1 ATOM 4911 C CE2 . TYR D 4 129 ? 32.190 -15.069 87.166 1.00 103.38 ? 129 TYR D CE2 1 ATOM 4912 C CZ . TYR D 4 129 ? 33.157 -14.894 88.136 1.00 101.53 ? 129 TYR D CZ 1 ATOM 4913 O OH . TYR D 4 129 ? 33.840 -13.705 88.209 1.00 102.70 ? 129 TYR D OH 1 ATOM 4914 N N . PRO D 4 130 ? 30.735 -21.830 88.280 1.00 108.56 ? 130 PRO D N 1 ATOM 4915 C CA . PRO D 4 130 ? 29.846 -22.994 88.269 1.00 109.54 ? 130 PRO D CA 1 ATOM 4916 C C . PRO D 4 130 ? 28.403 -22.640 88.628 1.00 109.04 ? 130 PRO D C 1 ATOM 4917 O O . PRO D 4 130 ? 28.168 -21.658 89.334 1.00 103.60 ? 130 PRO D O 1 ATOM 4918 C CB . PRO D 4 130 ? 30.445 -23.882 89.359 1.00 111.51 ? 130 PRO D CB 1 ATOM 4919 C CG . PRO D 4 130 ? 30.952 -22.905 90.362 1.00 111.92 ? 130 PRO D CG 1 ATOM 4920 C CD . PRO D 4 130 ? 31.452 -21.723 89.567 1.00 111.57 ? 130 PRO D CD 1 ATOM 4921 N N . LEU D 4 131 ? 27.459 -23.447 88.142 1.00 109.72 ? 131 LEU D N 1 ATOM 4922 C CA . LEU D 4 131 ? 26.039 -23.321 88.479 1.00 110.65 ? 131 LEU D CA 1 ATOM 4923 C C . LEU D 4 131 ? 25.519 -24.686 88.924 1.00 112.26 ? 131 LEU D C 1 ATOM 4924 O O . LEU D 4 131 ? 25.440 -25.617 88.112 1.00 112.34 ? 131 LEU D O 1 ATOM 4925 C CB . LEU D 4 131 ? 25.225 -22.815 87.278 1.00 109.52 ? 131 LEU D CB 1 ATOM 4926 C CG . LEU D 4 131 ? 25.724 -21.555 86.559 1.00 106.93 ? 131 LEU D CG 1 ATOM 4927 C CD1 . LEU D 4 131 ? 25.003 -21.377 85.225 1.00 103.99 ? 131 LEU D CD1 1 ATOM 4928 C CD2 . LEU D 4 131 ? 25.573 -20.330 87.453 1.00 105.42 ? 131 LEU D CD2 1 ATOM 4929 N N . ALA D 4 132 ? 25.182 -24.797 90.212 1.00 112.32 ? 132 ALA D N 1 ATOM 4930 C CA . ALA D 4 132 ? 24.678 -26.041 90.803 1.00 114.63 ? 132 ALA D CA 1 ATOM 4931 C C . ALA D 4 132 ? 23.456 -25.769 91.689 1.00 113.94 ? 132 ALA D C 1 ATOM 4932 O O . ALA D 4 132 ? 23.425 -24.759 92.394 1.00 111.97 ? 132 ALA D O 1 ATOM 4933 C CB . ALA D 4 132 ? 25.773 -26.712 91.614 1.00 117.37 ? 132 ALA D CB 1 ATOM 4934 N N . PRO D 4 133 ? 22.452 -26.675 91.667 1.00 115.76 ? 133 PRO D N 1 ATOM 4935 C CA . PRO D 4 133 ? 21.200 -26.443 92.397 1.00 117.40 ? 133 PRO D CA 1 ATOM 4936 C C . PRO D 4 133 ? 21.316 -26.633 93.912 1.00 119.04 ? 133 PRO D C 1 ATOM 4937 O O . PRO D 4 133 ? 22.267 -27.256 94.391 1.00 119.91 ? 133 PRO D O 1 ATOM 4938 C CB . PRO D 4 133 ? 20.259 -27.493 91.802 1.00 115.79 ? 133 PRO D CB 1 ATOM 4939 C CG . PRO D 4 133 ? 21.157 -28.619 91.434 1.00 114.64 ? 133 PRO D CG 1 ATOM 4940 C CD . PRO D 4 133 ? 22.446 -27.988 90.989 1.00 114.75 ? 133 PRO D CD 1 ATOM 4941 N N . GLY D 4 134 ? 20.339 -26.096 94.643 1.00 121.74 ? 134 GLY D N 1 ATOM 4942 C CA . GLY D 4 134 ? 20.284 -26.198 96.103 1.00 127.36 ? 134 GLY D CA 1 ATOM 4943 C C . GLY D 4 134 ? 19.550 -27.440 96.577 1.00 131.52 ? 134 GLY D C 1 ATOM 4944 O O . GLY D 4 134 ? 20.144 -28.317 97.209 1.00 130.27 ? 134 GLY D O 1 ATOM 4945 N N . THR D 4 135 ? 18.256 -27.504 96.262 1.00 137.35 ? 135 THR D N 1 ATOM 4946 C CA . THR D 4 135 ? 17.382 -28.613 96.673 1.00 141.91 ? 135 THR D CA 1 ATOM 4947 C C . THR D 4 135 ? 17.493 -29.802 95.702 1.00 144.08 ? 135 THR D C 1 ATOM 4948 O O . THR D 4 135 ? 17.777 -29.618 94.515 1.00 143.75 ? 135 THR D O 1 ATOM 4949 C CB . THR D 4 135 ? 15.905 -28.146 96.764 1.00 140.31 ? 135 THR D CB 1 ATOM 4950 O OG1 . THR D 4 135 ? 15.824 -26.947 97.546 1.00 140.07 ? 135 THR D OG1 1 ATOM 4951 C CG2 . THR D 4 135 ? 15.013 -29.212 97.398 1.00 138.59 ? 135 THR D CG2 1 ATOM 4952 N N . ALA D 4 136 ? 17.281 -31.012 96.225 1.00 145.13 ? 136 ALA D N 1 ATOM 4953 C CA . ALA D 4 136 ? 17.249 -32.246 95.430 1.00 145.00 ? 136 ALA D CA 1 ATOM 4954 C C . ALA D 4 136 ? 15.947 -33.001 95.725 1.00 149.31 ? 136 ALA D C 1 ATOM 4955 O O . ALA D 4 136 ? 15.811 -33.611 96.789 1.00 150.21 ? 136 ALA D O 1 ATOM 4956 C CB . ALA D 4 136 ? 18.457 -33.112 95.753 1.00 139.54 ? 136 ALA D CB 1 ATOM 4957 N N . LEU D 4 137 ? 14.998 -32.951 94.785 1.00 151.37 ? 137 LEU D N 1 ATOM 4958 C CA . LEU D 4 137 ? 13.648 -33.508 94.992 1.00 151.71 ? 137 LEU D CA 1 ATOM 4959 C C . LEU D 4 137 ? 13.607 -35.043 94.896 1.00 152.66 ? 137 LEU D C 1 ATOM 4960 O O . LEU D 4 137 ? 13.482 -35.717 95.922 1.00 154.17 ? 137 LEU D O 1 ATOM 4961 C CB . LEU D 4 137 ? 12.629 -32.874 94.021 1.00 149.58 ? 137 LEU D CB 1 ATOM 4962 C CG . LEU D 4 137 ? 12.281 -31.390 94.216 1.00 144.95 ? 137 LEU D CG 1 ATOM 4963 C CD1 . LEU D 4 137 ? 11.525 -30.852 93.008 1.00 140.93 ? 137 LEU D CD1 1 ATOM 4964 C CD2 . LEU D 4 137 ? 11.477 -31.164 95.490 1.00 141.73 ? 137 LEU D CD2 1 ATOM 4965 N N . LYS D 4 138 ? 13.718 -35.583 93.679 1.00 151.55 ? 138 LYS D N 1 ATOM 4966 C CA . LYS D 4 138 ? 13.581 -37.027 93.424 1.00 149.83 ? 138 LYS D CA 1 ATOM 4967 C C . LYS D 4 138 ? 14.842 -37.623 92.792 1.00 151.48 ? 138 LYS D C 1 ATOM 4968 O O . LYS D 4 138 ? 15.732 -36.890 92.346 1.00 149.43 ? 138 LYS D O 1 ATOM 4969 C CB . LYS D 4 138 ? 12.379 -37.286 92.507 1.00 145.28 ? 138 LYS D CB 1 ATOM 4970 C CG . LYS D 4 138 ? 11.029 -37.150 93.192 1.00 142.33 ? 138 LYS D CG 1 ATOM 4971 C CD . LYS D 4 138 ? 9.888 -37.630 92.302 1.00 142.19 ? 138 LYS D CD 1 ATOM 4972 C CE . LYS D 4 138 ? 9.599 -36.680 91.146 1.00 141.93 ? 138 LYS D CE 1 ATOM 4973 N NZ . LYS D 4 138 ? 9.142 -35.335 91.596 1.00 141.10 ? 138 LYS D NZ 1 ATOM 4974 N N . SER D 4 139 ? 14.906 -38.957 92.773 1.00 150.90 ? 139 SER D N 1 ATOM 4975 C CA . SER D 4 139 ? 15.948 -39.700 92.056 1.00 149.97 ? 139 SER D CA 1 ATOM 4976 C C . SER D 4 139 ? 15.428 -40.109 90.669 1.00 149.88 ? 139 SER D C 1 ATOM 4977 O O . SER D 4 139 ? 15.090 -41.274 90.433 1.00 148.61 ? 139 SER D O 1 ATOM 4978 C CB . SER D 4 139 ? 16.408 -40.921 92.865 1.00 147.80 ? 139 SER D CB 1 ATOM 4979 O OG . SER D 4 139 ? 15.316 -41.740 93.241 1.00 146.30 ? 139 SER D OG 1 ATOM 4980 N N . ASN D 4 140 ? 15.383 -39.127 89.764 1.00 150.42 ? 140 ASN D N 1 ATOM 4981 C CA . ASN D 4 140 ? 14.804 -39.275 88.409 1.00 148.53 ? 140 ASN D CA 1 ATOM 4982 C C . ASN D 4 140 ? 15.872 -39.147 87.313 1.00 148.78 ? 140 ASN D C 1 ATOM 4983 O O . ASN D 4 140 ? 16.997 -38.730 87.587 1.00 152.27 ? 140 ASN D O 1 ATOM 4984 C CB . ASN D 4 140 ? 13.652 -38.270 88.182 1.00 145.68 ? 140 ASN D CB 1 ATOM 4985 C CG . ASN D 4 140 ? 14.028 -36.826 88.509 1.00 142.88 ? 140 ASN D CG 1 ATOM 4986 O OD1 . ASN D 4 140 ? 15.161 -36.391 88.299 1.00 140.93 ? 140 ASN D OD1 1 ATOM 4987 N ND2 . ASN D 4 140 ? 13.062 -36.074 89.026 1.00 139.51 ? 140 ASN D ND2 1 ATOM 4988 N N . SER D 4 141 ? 15.513 -39.480 86.072 1.00 143.97 ? 141 SER D N 1 ATOM 4989 C CA . SER D 4 141 ? 16.492 -39.545 84.968 1.00 140.66 ? 141 SER D CA 1 ATOM 4990 C C . SER D 4 141 ? 16.912 -38.190 84.340 1.00 135.96 ? 141 SER D C 1 ATOM 4991 O O . SER D 4 141 ? 17.670 -38.189 83.363 1.00 136.17 ? 141 SER D O 1 ATOM 4992 C CB . SER D 4 141 ? 15.993 -40.506 83.872 1.00 138.38 ? 141 SER D CB 1 ATOM 4993 O OG . SER D 4 141 ? 14.835 -40.012 83.226 1.00 138.48 ? 141 SER D OG 1 ATOM 4994 N N . MET D 4 142 ? 16.456 -37.060 84.896 1.00 127.42 ? 142 MET D N 1 ATOM 4995 C CA . MET D 4 142 ? 16.766 -35.725 84.355 1.00 120.61 ? 142 MET D CA 1 ATOM 4996 C C . MET D 4 142 ? 17.143 -34.724 85.470 1.00 115.25 ? 142 MET D C 1 ATOM 4997 O O . MET D 4 142 ? 16.330 -34.456 86.356 1.00 109.53 ? 142 MET D O 1 ATOM 4998 C CB . MET D 4 142 ? 15.561 -35.176 83.565 1.00 121.15 ? 142 MET D CB 1 ATOM 4999 C CG . MET D 4 142 ? 14.825 -36.161 82.653 1.00 119.70 ? 142 MET D CG 1 ATOM 5000 S SD . MET D 4 142 ? 15.765 -36.781 81.241 1.00 116.66 ? 142 MET D SD 1 ATOM 5001 C CE . MET D 4 142 ? 14.479 -37.619 80.316 1.00 115.30 ? 142 MET D CE 1 ATOM 5002 N N . VAL D 4 143 ? 18.371 -34.192 85.420 1.00 112.43 ? 143 VAL D N 1 ATOM 5003 C CA . VAL D 4 143 ? 18.814 -33.063 86.276 1.00 109.65 ? 143 VAL D CA 1 ATOM 5004 C C . VAL D 4 143 ? 19.739 -32.113 85.485 1.00 108.55 ? 143 VAL D C 1 ATOM 5005 O O . VAL D 4 143 ? 20.766 -32.542 84.953 1.00 105.61 ? 143 VAL D O 1 ATOM 5006 C CB . VAL D 4 143 ? 19.493 -33.559 87.590 1.00 105.66 ? 143 VAL D CB 1 ATOM 5007 C CG1 . VAL D 4 143 ? 20.534 -32.573 88.130 1.00 103.48 ? 143 VAL D CG1 1 ATOM 5008 C CG2 . VAL D 4 143 ? 18.444 -33.826 88.663 1.00 104.09 ? 143 VAL D CG2 1 ATOM 5009 N N . THR D 4 144 ? 19.376 -30.828 85.434 1.00 108.47 ? 144 THR D N 1 ATOM 5010 C CA . THR D 4 144 ? 20.134 -29.815 84.686 1.00 109.56 ? 144 THR D CA 1 ATOM 5011 C C . THR D 4 144 ? 21.290 -29.235 85.511 1.00 111.27 ? 144 THR D C 1 ATOM 5012 O O . THR D 4 144 ? 21.113 -28.900 86.685 1.00 111.71 ? 144 THR D O 1 ATOM 5013 C CB . THR D 4 144 ? 19.232 -28.647 84.225 1.00 108.27 ? 144 THR D CB 1 ATOM 5014 O OG1 . THR D 4 144 ? 18.462 -28.160 85.331 1.00 112.64 ? 144 THR D OG1 1 ATOM 5015 C CG2 . THR D 4 144 ? 18.292 -29.088 83.116 1.00 106.37 ? 144 THR D CG2 1 ATOM 5016 N N . LEU D 4 145 ? 22.464 -29.129 84.885 1.00 113.54 ? 145 LEU D N 1 ATOM 5017 C CA . LEU D 4 145 ? 23.653 -28.482 85.470 1.00 116.37 ? 145 LEU D CA 1 ATOM 5018 C C . LEU D 4 145 ? 24.288 -27.580 84.413 1.00 110.35 ? 145 LEU D C 1 ATOM 5019 O O . LEU D 4 145 ? 24.185 -27.879 83.223 1.00 106.93 ? 145 LEU D O 1 ATOM 5020 C CB . LEU D 4 145 ? 24.668 -29.534 85.930 1.00 122.70 ? 145 LEU D CB 1 ATOM 5021 C CG . LEU D 4 145 ? 24.271 -30.408 87.128 1.00 126.34 ? 145 LEU D CG 1 ATOM 5022 C CD1 . LEU D 4 145 ? 25.105 -31.681 87.177 1.00 128.36 ? 145 LEU D CD1 1 ATOM 5023 C CD2 . LEU D 4 145 ? 24.400 -29.634 88.433 1.00 127.33 ? 145 LEU D CD2 1 ATOM 5024 N N . GLY D 4 146 ? 24.950 -26.498 84.834 1.00 105.91 ? 146 GLY D N 1 ATOM 5025 C CA . GLY D 4 146 ? 25.473 -25.509 83.879 1.00 103.80 ? 146 GLY D CA 1 ATOM 5026 C C . GLY D 4 146 ? 26.687 -24.691 84.279 1.00 102.44 ? 146 GLY D C 1 ATOM 5027 O O . GLY D 4 146 ? 27.094 -24.686 85.442 1.00 98.55 ? 146 GLY D O 1 ATOM 5028 N N . CYS D 4 147 ? 27.255 -24.005 83.282 1.00 106.29 ? 147 CYS D N 1 ATOM 5029 C CA . CYS D 4 147 ? 28.449 -23.155 83.427 1.00 112.56 ? 147 CYS D CA 1 ATOM 5030 C C . CYS D 4 147 ? 28.146 -21.715 83.003 1.00 109.96 ? 147 CYS D C 1 ATOM 5031 O O . CYS D 4 147 ? 27.481 -21.495 81.985 1.00 110.46 ? 147 CYS D O 1 ATOM 5032 C CB . CYS D 4 147 ? 29.602 -23.697 82.567 1.00 119.76 ? 147 CYS D CB 1 ATOM 5033 S SG . CYS D 4 147 ? 30.699 -24.871 83.402 1.00 130.75 ? 147 CYS D SG 1 ATOM 5034 N N . LEU D 4 148 ? 28.660 -20.751 83.770 1.00 104.84 ? 148 LEU D N 1 ATOM 5035 C CA . LEU D 4 148 ? 28.463 -19.319 83.505 1.00 101.30 ? 148 LEU D CA 1 ATOM 5036 C C . LEU D 4 148 ? 29.742 -18.699 82.947 1.00 97.28 ? 148 LEU D C 1 ATOM 5037 O O . LEU D 4 148 ? 30.692 -18.481 83.697 1.00 99.21 ? 148 LEU D O 1 ATOM 5038 C CB . LEU D 4 148 ? 28.050 -18.590 84.795 1.00 100.40 ? 148 LEU D CB 1 ATOM 5039 C CG . LEU D 4 148 ? 27.900 -17.059 84.766 1.00 98.33 ? 148 LEU D CG 1 ATOM 5040 C CD1 . LEU D 4 148 ? 26.956 -16.601 83.663 1.00 97.04 ? 148 LEU D CD1 1 ATOM 5041 C CD2 . LEU D 4 148 ? 27.422 -16.553 86.117 1.00 98.32 ? 148 LEU D CD2 1 ATOM 5042 N N . VAL D 4 149 ? 29.749 -18.406 81.645 1.00 93.06 ? 149 VAL D N 1 ATOM 5043 C CA . VAL D 4 149 ? 30.899 -17.785 80.966 1.00 90.42 ? 149 VAL D CA 1 ATOM 5044 C C . VAL D 4 149 ? 30.704 -16.266 80.956 1.00 86.81 ? 149 VAL D C 1 ATOM 5045 O O . VAL D 4 149 ? 29.882 -15.765 80.189 1.00 83.66 ? 149 VAL D O 1 ATOM 5046 C CB . VAL D 4 149 ? 31.058 -18.306 79.508 1.00 88.88 ? 149 VAL D CB 1 ATOM 5047 C CG1 . VAL D 4 149 ? 32.369 -17.821 78.899 1.00 88.41 ? 149 VAL D CG1 1 ATOM 5048 C CG2 . VAL D 4 149 ? 30.983 -19.828 79.461 1.00 87.86 ? 149 VAL D CG2 1 ATOM 5049 N N . LYS D 4 150 ? 31.457 -15.539 81.789 1.00 84.88 ? 150 LYS D N 1 ATOM 5050 C CA . LYS D 4 150 ? 31.252 -14.088 81.969 1.00 85.61 ? 150 LYS D CA 1 ATOM 5051 C C . LYS D 4 150 ? 32.462 -13.224 81.602 1.00 82.75 ? 150 LYS D C 1 ATOM 5052 O O . LYS D 4 150 ? 33.576 -13.484 82.045 1.00 81.82 ? 150 LYS D O 1 ATOM 5053 C CB . LYS D 4 150 ? 30.845 -13.791 83.418 1.00 85.92 ? 150 LYS D CB 1 ATOM 5054 C CG . LYS D 4 150 ? 29.989 -12.540 83.571 1.00 87.46 ? 150 LYS D CG 1 ATOM 5055 C CD . LYS D 4 150 ? 29.527 -12.330 85.008 1.00 89.45 ? 150 LYS D CD 1 ATOM 5056 C CE . LYS D 4 150 ? 30.487 -11.453 85.801 1.00 92.19 ? 150 LYS D CE 1 ATOM 5057 N NZ . LYS D 4 150 ? 30.224 -10.003 85.573 1.00 91.96 ? 150 LYS D NZ 1 ATOM 5058 N N . GLY D 4 151 ? 32.224 -12.201 80.785 1.00 83.25 ? 151 GLY D N 1 ATOM 5059 C CA . GLY D 4 151 ? 33.172 -11.107 80.592 1.00 87.45 ? 151 GLY D CA 1 ATOM 5060 C C . GLY D 4 151 ? 34.394 -11.429 79.753 1.00 91.00 ? 151 GLY D C 1 ATOM 5061 O O . GLY D 4 151 ? 35.521 -11.317 80.237 1.00 95.01 ? 151 GLY D O 1 ATOM 5062 N N . TYR D 4 152 ? 34.168 -11.808 78.495 1.00 92.68 ? 152 TYR D N 1 ATOM 5063 C CA . TYR D 4 152 ? 35.248 -12.095 77.540 1.00 93.35 ? 152 TYR D CA 1 ATOM 5064 C C . TYR D 4 152 ? 35.070 -11.275 76.264 1.00 93.79 ? 152 TYR D C 1 ATOM 5065 O O . TYR D 4 152 ? 33.954 -10.837 75.953 1.00 90.44 ? 152 TYR D O 1 ATOM 5066 C CB . TYR D 4 152 ? 35.301 -13.596 77.213 1.00 95.36 ? 152 TYR D CB 1 ATOM 5067 C CG . TYR D 4 152 ? 34.097 -14.138 76.462 1.00 97.64 ? 152 TYR D CG 1 ATOM 5068 C CD1 . TYR D 4 152 ? 34.045 -14.108 75.067 1.00 97.55 ? 152 TYR D CD1 1 ATOM 5069 C CD2 . TYR D 4 152 ? 33.013 -14.690 77.145 1.00 98.96 ? 152 TYR D CD2 1 ATOM 5070 C CE1 . TYR D 4 152 ? 32.947 -14.598 74.375 1.00 97.39 ? 152 TYR D CE1 1 ATOM 5071 C CE2 . TYR D 4 152 ? 31.911 -15.187 76.460 1.00 98.12 ? 152 TYR D CE2 1 ATOM 5072 C CZ . TYR D 4 152 ? 31.884 -15.139 75.076 1.00 98.60 ? 152 TYR D CZ 1 ATOM 5073 O OH . TYR D 4 152 ? 30.799 -15.623 74.384 1.00 100.27 ? 152 TYR D OH 1 ATOM 5074 N N . PHE D 4 153 ? 36.172 -11.078 75.533 1.00 93.21 ? 153 PHE D N 1 ATOM 5075 C CA . PHE D 4 153 ? 36.151 -10.356 74.251 1.00 93.24 ? 153 PHE D CA 1 ATOM 5076 C C . PHE D 4 153 ? 37.237 -10.882 73.297 1.00 94.81 ? 153 PHE D C 1 ATOM 5077 O O . PHE D 4 153 ? 38.379 -11.034 73.731 1.00 95.12 ? 153 PHE D O 1 ATOM 5078 C CB . PHE D 4 153 ? 36.356 -8.857 74.489 1.00 88.05 ? 153 PHE D CB 1 ATOM 5079 C CG . PHE D 4 153 ? 36.007 -7.998 73.309 1.00 82.73 ? 153 PHE D CG 1 ATOM 5080 C CD1 . PHE D 4 153 ? 34.716 -7.505 73.151 1.00 82.69 ? 153 PHE D CD1 1 ATOM 5081 C CD2 . PHE D 4 153 ? 36.968 -7.669 72.360 1.00 81.58 ? 153 PHE D CD2 1 ATOM 5082 C CE1 . PHE D 4 153 ? 34.386 -6.703 72.065 1.00 82.45 ? 153 PHE D CE1 1 ATOM 5083 C CE2 . PHE D 4 153 ? 36.644 -6.868 71.272 1.00 81.88 ? 153 PHE D CE2 1 ATOM 5084 C CZ . PHE D 4 153 ? 35.351 -6.383 71.123 1.00 81.01 ? 153 PHE D CZ 1 ATOM 5085 N N . PRO D 4 154 ? 36.927 -11.165 72.021 1.00 100.00 ? 154 PRO D N 1 ATOM 5086 C CA . PRO D 4 154 ? 35.591 -11.089 71.403 1.00 100.09 ? 154 PRO D CA 1 ATOM 5087 C C . PRO D 4 154 ? 34.992 -12.475 71.143 1.00 99.53 ? 154 PRO D C 1 ATOM 5088 O O . PRO D 4 154 ? 35.585 -13.494 71.524 1.00 94.61 ? 154 PRO D O 1 ATOM 5089 C CB . PRO D 4 154 ? 35.883 -10.392 70.076 1.00 99.25 ? 154 PRO D CB 1 ATOM 5090 C CG . PRO D 4 154 ? 37.242 -10.888 69.708 1.00 102.35 ? 154 PRO D CG 1 ATOM 5091 C CD . PRO D 4 154 ? 37.981 -11.210 70.989 1.00 102.44 ? 154 PRO D CD 1 ATOM 5092 N N . GLU D 4 155 ? 33.826 -12.499 70.495 1.00 101.63 ? 155 GLU D N 1 ATOM 5093 C CA . GLU D 4 155 ? 33.186 -13.754 70.065 1.00 105.30 ? 155 GLU D CA 1 ATOM 5094 C C . GLU D 4 155 ? 34.002 -14.440 68.958 1.00 109.27 ? 155 GLU D C 1 ATOM 5095 O O . GLU D 4 155 ? 34.784 -13.771 68.275 1.00 109.82 ? 155 GLU D O 1 ATOM 5096 C CB . GLU D 4 155 ? 31.744 -13.505 69.585 1.00 102.89 ? 155 GLU D CB 1 ATOM 5097 C CG . GLU D 4 155 ? 30.691 -13.717 70.663 1.00 101.15 ? 155 GLU D CG 1 ATOM 5098 C CD . GLU D 4 155 ? 29.274 -13.567 70.140 1.00 99.41 ? 155 GLU D CD 1 ATOM 5099 O OE1 . GLU D 4 155 ? 28.999 -12.575 69.433 1.00 99.03 ? 155 GLU D OE1 1 ATOM 5100 O OE2 . GLU D 4 155 ? 28.432 -14.438 70.443 1.00 96.89 ? 155 GLU D OE2 1 ATOM 5101 N N . PRO D 4 156 ? 33.835 -15.754 68.761 1.00 115.74 ? 156 PRO D N 1 ATOM 5102 C CA . PRO D 4 156 ? 32.902 -16.623 69.497 1.00 117.40 ? 156 PRO D CA 1 ATOM 5103 C C . PRO D 4 156 ? 33.528 -17.247 70.750 1.00 118.38 ? 156 PRO D C 1 ATOM 5104 O O . PRO D 4 156 ? 34.616 -16.848 71.161 1.00 115.38 ? 156 PRO D O 1 ATOM 5105 C CB . PRO D 4 156 ? 32.575 -17.701 68.459 1.00 116.83 ? 156 PRO D CB 1 ATOM 5106 C CG . PRO D 4 156 ? 33.838 -17.839 67.677 1.00 116.48 ? 156 PRO D CG 1 ATOM 5107 C CD . PRO D 4 156 ? 34.499 -16.483 67.664 1.00 117.19 ? 156 PRO D CD 1 ATOM 5108 N N . VAL D 4 157 ? 32.813 -18.190 71.362 1.00 118.47 ? 157 VAL D N 1 ATOM 5109 C CA . VAL D 4 157 ? 33.345 -19.035 72.435 1.00 119.58 ? 157 VAL D CA 1 ATOM 5110 C C . VAL D 4 157 ? 32.766 -20.450 72.255 1.00 121.87 ? 157 VAL D C 1 ATOM 5111 O O . VAL D 4 157 ? 31.643 -20.598 71.759 1.00 117.80 ? 157 VAL D O 1 ATOM 5112 C CB . VAL D 4 157 ? 33.028 -18.432 73.831 1.00 116.91 ? 157 VAL D CB 1 ATOM 5113 C CG1 . VAL D 4 157 ? 31.576 -18.662 74.233 1.00 117.41 ? 157 VAL D CG1 1 ATOM 5114 C CG2 . VAL D 4 157 ? 33.967 -18.978 74.896 1.00 114.82 ? 157 VAL D CG2 1 ATOM 5115 N N . THR D 4 158 ? 33.531 -21.476 72.637 1.00 125.35 ? 158 THR D N 1 ATOM 5116 C CA . THR D 4 158 ? 33.118 -22.881 72.452 1.00 126.43 ? 158 THR D CA 1 ATOM 5117 C C . THR D 4 158 ? 33.261 -23.684 73.751 1.00 131.62 ? 158 THR D C 1 ATOM 5118 O O . THR D 4 158 ? 34.341 -23.745 74.349 1.00 131.88 ? 158 THR D O 1 ATOM 5119 C CB . THR D 4 158 ? 33.866 -23.572 71.278 1.00 124.98 ? 158 THR D CB 1 ATOM 5120 O OG1 . THR D 4 158 ? 33.394 -24.917 71.129 1.00 124.71 ? 158 THR D OG1 1 ATOM 5121 C CG2 . THR D 4 158 ? 35.381 -23.602 71.478 1.00 123.43 ? 158 THR D CG2 1 ATOM 5122 N N . VAL D 4 159 ? 32.153 -24.299 74.168 1.00 135.79 ? 159 VAL D N 1 ATOM 5123 C CA . VAL D 4 159 ? 32.052 -24.987 75.454 1.00 140.68 ? 159 VAL D CA 1 ATOM 5124 C C . VAL D 4 159 ? 32.093 -26.502 75.249 1.00 139.89 ? 159 VAL D C 1 ATOM 5125 O O . VAL D 4 159 ? 31.459 -27.031 74.333 1.00 136.70 ? 159 VAL D O 1 ATOM 5126 C CB . VAL D 4 159 ? 30.744 -24.608 76.191 1.00 145.02 ? 159 VAL D CB 1 ATOM 5127 C CG1 . VAL D 4 159 ? 30.768 -25.103 77.636 1.00 146.68 ? 159 VAL D CG1 1 ATOM 5128 C CG2 . VAL D 4 159 ? 30.519 -23.100 76.146 1.00 144.86 ? 159 VAL D CG2 1 ATOM 5129 N N . THR D 4 160 ? 32.842 -27.180 76.116 1.00 139.79 ? 160 THR D N 1 ATOM 5130 C CA . THR D 4 160 ? 32.942 -28.637 76.130 1.00 142.03 ? 160 THR D CA 1 ATOM 5131 C C . THR D 4 160 ? 32.468 -29.140 77.497 1.00 142.60 ? 160 THR D C 1 ATOM 5132 O O . THR D 4 160 ? 32.690 -28.477 78.512 1.00 141.49 ? 160 THR D O 1 ATOM 5133 C CB . THR D 4 160 ? 34.391 -29.103 75.857 1.00 142.55 ? 160 THR D CB 1 ATOM 5134 O OG1 . THR D 4 160 ? 35.210 -28.881 77.011 1.00 142.80 ? 160 THR D OG1 1 ATOM 5135 C CG2 . THR D 4 160 ? 34.992 -28.357 74.667 1.00 140.71 ? 160 THR D CG2 1 ATOM 5136 N N . TRP D 4 161 ? 31.819 -30.303 77.515 1.00 145.42 ? 161 TRP D N 1 ATOM 5137 C CA . TRP D 4 161 ? 31.268 -30.895 78.743 1.00 147.27 ? 161 TRP D CA 1 ATOM 5138 C C . TRP D 4 161 ? 31.825 -32.306 78.952 1.00 147.98 ? 161 TRP D C 1 ATOM 5139 O O . TRP D 4 161 ? 31.609 -33.177 78.105 1.00 154.08 ? 161 TRP D O 1 ATOM 5140 C CB . TRP D 4 161 ? 29.738 -30.942 78.659 1.00 146.62 ? 161 TRP D CB 1 ATOM 5141 C CG . TRP D 4 161 ? 29.068 -29.673 79.079 1.00 141.77 ? 161 TRP D CG 1 ATOM 5142 C CD1 . TRP D 4 161 ? 28.602 -28.681 78.265 1.00 140.86 ? 161 TRP D CD1 1 ATOM 5143 C CD2 . TRP D 4 161 ? 28.787 -29.261 80.419 1.00 139.51 ? 161 TRP D CD2 1 ATOM 5144 N NE1 . TRP D 4 161 ? 28.048 -27.673 79.018 1.00 142.24 ? 161 TRP D NE1 1 ATOM 5145 C CE2 . TRP D 4 161 ? 28.149 -28.004 80.344 1.00 142.50 ? 161 TRP D CE2 1 ATOM 5146 C CE3 . TRP D 4 161 ? 29.017 -29.831 81.680 1.00 139.75 ? 161 TRP D CE3 1 ATOM 5147 C CZ2 . TRP D 4 161 ? 27.733 -27.304 81.483 1.00 145.57 ? 161 TRP D CZ2 1 ATOM 5148 C CZ3 . TRP D 4 161 ? 28.599 -29.139 82.816 1.00 141.66 ? 161 TRP D CZ3 1 ATOM 5149 C CH2 . TRP D 4 161 ? 27.966 -27.886 82.707 1.00 145.80 ? 161 TRP D CH2 1 ATOM 5150 N N . ASN D 4 162 ? 32.498 -32.525 80.091 1.00 141.33 ? 162 ASN D N 1 ATOM 5151 C CA . ASN D 4 162 ? 33.280 -33.752 80.380 1.00 135.54 ? 162 ASN D CA 1 ATOM 5152 C C . ASN D 4 162 ? 33.902 -34.398 79.123 1.00 132.69 ? 162 ASN D C 1 ATOM 5153 O O . ASN D 4 162 ? 33.438 -35.437 78.641 1.00 134.27 ? 162 ASN D O 1 ATOM 5154 C CB . ASN D 4 162 ? 32.486 -34.769 81.241 1.00 133.19 ? 162 ASN D CB 1 ATOM 5155 C CG . ASN D 4 162 ? 31.061 -35.005 80.751 1.00 133.20 ? 162 ASN D CG 1 ATOM 5156 O OD1 . ASN D 4 162 ? 30.108 -34.855 81.513 1.00 128.04 ? 162 ASN D OD1 1 ATOM 5157 N ND2 . ASN D 4 162 ? 30.910 -35.393 79.489 1.00 132.36 ? 162 ASN D ND2 1 ATOM 5158 N N . SER D 4 163 ? 34.953 -33.749 78.615 1.00 124.93 ? 163 SER D N 1 ATOM 5159 C CA . SER D 4 163 ? 35.556 -34.044 77.304 1.00 121.30 ? 163 SER D CA 1 ATOM 5160 C C . SER D 4 163 ? 34.546 -33.809 76.162 1.00 117.20 ? 163 SER D C 1 ATOM 5161 O O . SER D 4 163 ? 34.382 -32.670 75.725 1.00 113.99 ? 163 SER D O 1 ATOM 5162 C CB . SER D 4 163 ? 36.209 -35.439 77.263 1.00 121.78 ? 163 SER D CB 1 ATOM 5163 O OG . SER D 4 163 ? 37.352 -35.489 78.096 1.00 122.00 ? 163 SER D OG 1 ATOM 5164 N N . GLY D 4 164 ? 33.890 -34.867 75.678 1.00 116.13 ? 164 GLY D N 1 ATOM 5165 C CA . GLY D 4 164 ? 32.778 -34.742 74.726 1.00 116.15 ? 164 GLY D CA 1 ATOM 5166 C C . GLY D 4 164 ? 31.694 -35.803 74.872 1.00 118.16 ? 164 GLY D C 1 ATOM 5167 O O . GLY D 4 164 ? 30.962 -36.073 73.915 1.00 115.25 ? 164 GLY D O 1 ATOM 5168 N N . ALA D 4 165 ? 31.566 -36.378 76.073 1.00 120.77 ? 165 ALA D N 1 ATOM 5169 C CA . ALA D 4 165 ? 30.584 -37.435 76.345 1.00 121.75 ? 165 ALA D CA 1 ATOM 5170 C C . ALA D 4 165 ? 29.185 -36.882 76.628 1.00 123.32 ? 165 ALA D C 1 ATOM 5171 O O . ALA D 4 165 ? 28.238 -37.659 76.758 1.00 128.50 ? 165 ALA D O 1 ATOM 5172 C CB . ALA D 4 165 ? 31.048 -38.306 77.507 1.00 119.14 ? 165 ALA D CB 1 ATOM 5173 N N . LEU D 4 166 ? 29.060 -35.558 76.742 1.00 119.64 ? 166 LEU D N 1 ATOM 5174 C CA . LEU D 4 166 ? 27.766 -34.904 76.903 1.00 117.50 ? 166 LEU D CA 1 ATOM 5175 C C . LEU D 4 166 ? 26.880 -35.114 75.676 1.00 118.92 ? 166 LEU D C 1 ATOM 5176 O O . LEU D 4 166 ? 25.778 -35.649 75.794 1.00 125.81 ? 166 LEU D O 1 ATOM 5177 C CB . LEU D 4 166 ? 27.960 -33.412 77.156 1.00 113.83 ? 166 LEU D CB 1 ATOM 5178 N N . SER D 4 167 ? 27.376 -34.696 74.511 1.00 115.53 ? 167 SER D N 1 ATOM 5179 C CA . SER D 4 167 ? 26.705 -34.906 73.215 1.00 115.73 ? 167 SER D CA 1 ATOM 5180 C C . SER D 4 167 ? 25.275 -34.301 73.134 1.00 121.15 ? 167 SER D C 1 ATOM 5181 O O . SER D 4 167 ? 25.146 -33.077 73.071 1.00 123.19 ? 167 SER D O 1 ATOM 5182 C CB . SER D 4 167 ? 26.757 -36.393 72.818 1.00 112.80 ? 167 SER D CB 1 ATOM 5183 O OG . SER D 4 167 ? 26.097 -36.624 71.585 1.00 106.32 ? 167 SER D OG 1 ATOM 5184 N N . SER D 4 168 ? 24.224 -35.134 73.159 1.00 124.75 ? 168 SER D N 1 ATOM 5185 C CA . SER D 4 168 ? 22.837 -34.679 72.903 1.00 126.01 ? 168 SER D CA 1 ATOM 5186 C C . SER D 4 168 ? 22.142 -33.985 74.086 1.00 125.85 ? 168 SER D C 1 ATOM 5187 O O . SER D 4 168 ? 21.104 -33.348 73.895 1.00 126.82 ? 168 SER D O 1 ATOM 5188 C CB . SER D 4 168 ? 21.956 -35.843 72.414 1.00 127.02 ? 168 SER D CB 1 ATOM 5189 O OG . SER D 4 168 ? 22.206 -36.139 71.051 1.00 129.34 ? 168 SER D OG 1 ATOM 5190 N N . GLY D 4 169 ? 22.698 -34.111 75.291 1.00 125.97 ? 169 GLY D N 1 ATOM 5191 C CA . GLY D 4 169 ? 22.121 -33.489 76.487 1.00 126.02 ? 169 GLY D CA 1 ATOM 5192 C C . GLY D 4 169 ? 22.371 -31.996 76.676 1.00 125.69 ? 169 GLY D C 1 ATOM 5193 O O . GLY D 4 169 ? 21.675 -31.354 77.466 1.00 126.38 ? 169 GLY D O 1 ATOM 5194 N N . VAL D 4 170 ? 23.347 -31.438 75.956 1.00 123.56 ? 170 VAL D N 1 ATOM 5195 C CA . VAL D 4 170 ? 23.823 -30.062 76.195 1.00 119.77 ? 170 VAL D CA 1 ATOM 5196 C C . VAL D 4 170 ? 22.973 -29.001 75.477 1.00 110.66 ? 170 VAL D C 1 ATOM 5197 O O . VAL D 4 170 ? 22.475 -29.227 74.374 1.00 108.04 ? 170 VAL D O 1 ATOM 5198 C CB . VAL D 4 170 ? 25.332 -29.926 75.818 1.00 122.56 ? 170 VAL D CB 1 ATOM 5199 C CG1 . VAL D 4 170 ? 25.799 -28.472 75.712 1.00 123.57 ? 170 VAL D CG1 1 ATOM 5200 C CG2 . VAL D 4 170 ? 26.191 -30.668 76.831 1.00 122.34 ? 170 VAL D CG2 1 ATOM 5201 N N . HIS D 4 171 ? 22.801 -27.857 76.143 1.00 102.82 ? 171 HIS D N 1 ATOM 5202 C CA . HIS D 4 171 ? 22.327 -26.616 75.528 1.00 95.70 ? 171 HIS D CA 1 ATOM 5203 C C . HIS D 4 171 ? 23.351 -25.528 75.824 1.00 90.22 ? 171 HIS D C 1 ATOM 5204 O O . HIS D 4 171 ? 23.862 -25.452 76.946 1.00 86.45 ? 171 HIS D O 1 ATOM 5205 C CB . HIS D 4 171 ? 20.982 -26.179 76.121 1.00 95.57 ? 171 HIS D CB 1 ATOM 5206 C CG . HIS D 4 171 ? 19.786 -26.684 75.380 1.00 94.13 ? 171 HIS D CG 1 ATOM 5207 N ND1 . HIS D 4 171 ? 19.712 -26.703 74.004 1.00 94.77 ? 171 HIS D ND1 1 ATOM 5208 C CD2 . HIS D 4 171 ? 18.596 -27.149 75.829 1.00 91.99 ? 171 HIS D CD2 1 ATOM 5209 C CE1 . HIS D 4 171 ? 18.537 -27.182 73.636 1.00 96.87 ? 171 HIS D CE1 1 ATOM 5210 N NE2 . HIS D 4 171 ? 17.840 -27.459 74.725 1.00 94.01 ? 171 HIS D NE2 1 ATOM 5211 N N . THR D 4 172 ? 23.661 -24.708 74.821 1.00 85.15 ? 172 THR D N 1 ATOM 5212 C CA . THR D 4 172 ? 24.417 -23.462 75.026 1.00 84.12 ? 172 THR D CA 1 ATOM 5213 C C . THR D 4 172 ? 23.674 -22.335 74.306 1.00 81.11 ? 172 THR D C 1 ATOM 5214 O O . THR D 4 172 ? 23.064 -22.560 73.256 1.00 79.78 ? 172 THR D O 1 ATOM 5215 C CB . THR D 4 172 ? 25.892 -23.542 74.549 1.00 84.02 ? 172 THR D CB 1 ATOM 5216 O OG1 . THR D 4 172 ? 25.990 -23.163 73.170 1.00 86.92 ? 172 THR D OG1 1 ATOM 5217 C CG2 . THR D 4 172 ? 26.486 -24.942 74.741 1.00 82.08 ? 172 THR D CG2 1 ATOM 5218 N N . PHE D 4 173 ? 23.738 -21.131 74.873 1.00 77.20 ? 173 PHE D N 1 ATOM 5219 C CA . PHE D 4 173 ? 22.861 -20.027 74.472 1.00 73.67 ? 173 PHE D CA 1 ATOM 5220 C C . PHE D 4 173 ? 23.645 -18.907 73.786 1.00 70.13 ? 173 PHE D C 1 ATOM 5221 O O . PHE D 4 173 ? 24.854 -18.798 73.989 1.00 65.87 ? 173 PHE D O 1 ATOM 5222 C CB . PHE D 4 173 ? 22.123 -19.475 75.700 1.00 73.16 ? 173 PHE D CB 1 ATOM 5223 C CG . PHE D 4 173 ? 21.367 -20.521 76.485 1.00 72.95 ? 173 PHE D CG 1 ATOM 5224 C CD1 . PHE D 4 173 ? 22.009 -21.281 77.466 1.00 72.33 ? 173 PHE D CD1 1 ATOM 5225 C CD2 . PHE D 4 173 ? 20.007 -20.742 76.253 1.00 73.74 ? 173 PHE D CD2 1 ATOM 5226 C CE1 . PHE D 4 173 ? 21.317 -22.242 78.191 1.00 71.98 ? 173 PHE D CE1 1 ATOM 5227 C CE2 . PHE D 4 173 ? 19.308 -21.706 76.975 1.00 73.49 ? 173 PHE D CE2 1 ATOM 5228 C CZ . PHE D 4 173 ? 19.966 -22.457 77.943 1.00 73.78 ? 173 PHE D CZ 1 ATOM 5229 N N . PRO D 4 174 ? 22.963 -18.073 72.967 1.00 72.16 ? 174 PRO D N 1 ATOM 5230 C CA . PRO D 4 174 ? 23.633 -16.899 72.404 1.00 74.88 ? 174 PRO D CA 1 ATOM 5231 C C . PRO D 4 174 ? 24.140 -15.949 73.487 1.00 77.69 ? 174 PRO D C 1 ATOM 5232 O O . PRO D 4 174 ? 23.426 -15.693 74.460 1.00 80.51 ? 174 PRO D O 1 ATOM 5233 C CB . PRO D 4 174 ? 22.532 -16.218 71.573 1.00 73.49 ? 174 PRO D CB 1 ATOM 5234 C CG . PRO D 4 174 ? 21.583 -17.306 71.234 1.00 72.93 ? 174 PRO D CG 1 ATOM 5235 C CD . PRO D 4 174 ? 21.596 -18.222 72.425 1.00 74.32 ? 174 PRO D CD 1 ATOM 5236 N N . ALA D 4 175 ? 25.361 -15.448 73.314 1.00 78.59 ? 175 ALA D N 1 ATOM 5237 C CA . ALA D 4 175 ? 25.945 -14.481 74.241 1.00 80.14 ? 175 ALA D CA 1 ATOM 5238 C C . ALA D 4 175 ? 25.281 -13.110 74.094 1.00 82.26 ? 175 ALA D C 1 ATOM 5239 O O . ALA D 4 175 ? 24.616 -12.833 73.089 1.00 79.52 ? 175 ALA D O 1 ATOM 5240 C CB . ALA D 4 175 ? 27.445 -14.368 74.017 1.00 80.52 ? 175 ALA D CB 1 ATOM 5241 N N . VAL D 4 176 ? 25.457 -12.268 75.112 1.00 85.27 ? 176 VAL D N 1 ATOM 5242 C CA . VAL D 4 176 ? 24.897 -10.914 75.125 1.00 86.75 ? 176 VAL D CA 1 ATOM 5243 C C . VAL D 4 176 ? 25.970 -9.918 75.556 1.00 85.69 ? 176 VAL D C 1 ATOM 5244 O O . VAL D 4 176 ? 26.823 -10.243 76.387 1.00 83.50 ? 176 VAL D O 1 ATOM 5245 C CB . VAL D 4 176 ? 23.680 -10.802 76.075 1.00 89.58 ? 176 VAL D CB 1 ATOM 5246 C CG1 . VAL D 4 176 ? 22.933 -9.491 75.837 1.00 91.58 ? 176 VAL D CG1 1 ATOM 5247 C CG2 . VAL D 4 176 ? 22.738 -11.991 75.900 1.00 87.80 ? 176 VAL D CG2 1 ATOM 5248 N N . LEU D 4 177 ? 25.911 -8.714 74.980 1.00 87.56 ? 177 LEU D N 1 ATOM 5249 C CA . LEU D 4 177 ? 26.823 -7.614 75.317 1.00 90.44 ? 177 LEU D CA 1 ATOM 5250 C C . LEU D 4 177 ? 26.198 -6.716 76.377 1.00 91.96 ? 177 LEU D C 1 ATOM 5251 O O . LEU D 4 177 ? 25.083 -6.230 76.191 1.00 90.10 ? 177 LEU D O 1 ATOM 5252 C CB . LEU D 4 177 ? 27.161 -6.782 74.073 1.00 90.36 ? 177 LEU D CB 1 ATOM 5253 C CG . LEU D 4 177 ? 28.364 -7.309 73.287 1.00 93.21 ? 177 LEU D CG 1 ATOM 5254 C CD1 . LEU D 4 177 ? 28.316 -6.892 71.822 1.00 94.74 ? 177 LEU D CD1 1 ATOM 5255 C CD2 . LEU D 4 177 ? 29.670 -6.867 73.933 1.00 93.71 ? 177 LEU D CD2 1 ATOM 5256 N N . GLN D 4 178 ? 26.921 -6.497 77.476 1.00 94.24 ? 178 GLN D N 1 ATOM 5257 C CA . GLN D 4 178 ? 26.437 -5.663 78.577 1.00 97.68 ? 178 GLN D CA 1 ATOM 5258 C C . GLN D 4 178 ? 27.083 -4.280 78.538 1.00 98.46 ? 178 GLN D C 1 ATOM 5259 O O . GLN D 4 178 ? 26.382 -3.268 78.608 1.00 102.63 ? 178 GLN D O 1 ATOM 5260 C CB . GLN D 4 178 ? 26.699 -6.354 79.918 1.00 101.16 ? 178 GLN D CB 1 ATOM 5261 C CG . GLN D 4 178 ? 25.801 -5.876 81.056 1.00 99.96 ? 178 GLN D CG 1 ATOM 5262 C CD . GLN D 4 178 ? 25.826 -6.796 82.270 1.00 99.56 ? 178 GLN D CD 1 ATOM 5263 O OE1 . GLN D 4 178 ? 26.642 -7.717 82.360 1.00 95.57 ? 178 GLN D OE1 1 ATOM 5264 N NE2 . GLN D 4 178 ? 24.922 -6.548 83.213 1.00 100.45 ? 178 GLN D NE2 1 ATOM 5265 N N . SER D 4 179 ? 28.411 -4.243 78.437 1.00 96.52 ? 179 SER D N 1 ATOM 5266 C CA . SER D 4 179 ? 29.151 -2.986 78.258 1.00 97.31 ? 179 SER D CA 1 ATOM 5267 C C . SER D 4 179 ? 30.466 -3.269 77.545 1.00 98.13 ? 179 SER D C 1 ATOM 5268 O O . SER D 4 179 ? 31.540 -3.240 78.149 1.00 101.93 ? 179 SER D O 1 ATOM 5269 C CB . SER D 4 179 ? 29.403 -2.292 79.604 1.00 97.36 ? 179 SER D CB 1 ATOM 5270 O OG . SER D 4 179 ? 28.223 -1.698 80.109 1.00 96.29 ? 179 SER D OG 1 ATOM 5271 N N . GLY D 4 180 ? 30.361 -3.579 76.257 1.00 96.96 ? 180 GLY D N 1 ATOM 5272 C CA . GLY D 4 180 ? 31.526 -3.856 75.423 1.00 93.37 ? 180 GLY D CA 1 ATOM 5273 C C . GLY D 4 180 ? 32.247 -5.177 75.664 1.00 92.16 ? 180 GLY D C 1 ATOM 5274 O O . GLY D 4 180 ? 33.330 -5.380 75.111 1.00 95.27 ? 180 GLY D O 1 ATOM 5275 N N . LEU D 4 181 ? 31.671 -6.076 76.470 1.00 88.20 ? 181 LEU D N 1 ATOM 5276 C CA . LEU D 4 181 ? 32.240 -7.416 76.672 1.00 87.79 ? 181 LEU D CA 1 ATOM 5277 C C . LEU D 4 181 ? 31.143 -8.478 76.834 1.00 85.33 ? 181 LEU D C 1 ATOM 5278 O O . LEU D 4 181 ? 30.123 -8.253 77.492 1.00 83.49 ? 181 LEU D O 1 ATOM 5279 C CB . LEU D 4 181 ? 33.241 -7.443 77.839 1.00 88.90 ? 181 LEU D CB 1 ATOM 5280 C CG . LEU D 4 181 ? 32.756 -7.474 79.294 1.00 91.19 ? 181 LEU D CG 1 ATOM 5281 C CD1 . LEU D 4 181 ? 33.923 -7.753 80.233 1.00 89.97 ? 181 LEU D CD1 1 ATOM 5282 C CD2 . LEU D 4 181 ? 32.053 -6.176 79.674 1.00 93.01 ? 181 LEU D CD2 1 ATOM 5283 N N . TYR D 4 182 ? 31.379 -9.633 76.221 1.00 84.66 ? 182 TYR D N 1 ATOM 5284 C CA . TYR D 4 182 ? 30.357 -10.662 76.058 1.00 86.28 ? 182 TYR D CA 1 ATOM 5285 C C . TYR D 4 182 ? 30.213 -11.517 77.307 1.00 85.15 ? 182 TYR D C 1 ATOM 5286 O O . TYR D 4 182 ? 31.109 -11.570 78.149 1.00 84.73 ? 182 TYR D O 1 ATOM 5287 C CB . TYR D 4 182 ? 30.682 -11.566 74.855 1.00 87.50 ? 182 TYR D CB 1 ATOM 5288 C CG . TYR D 4 182 ? 30.404 -10.945 73.502 1.00 84.10 ? 182 TYR D CG 1 ATOM 5289 C CD1 . TYR D 4 182 ? 29.112 -10.928 72.976 1.00 84.03 ? 182 TYR D CD1 1 ATOM 5290 C CD2 . TYR D 4 182 ? 31.433 -10.394 72.735 1.00 84.50 ? 182 TYR D CD2 1 ATOM 5291 C CE1 . TYR D 4 182 ? 28.848 -10.372 71.729 1.00 85.53 ? 182 TYR D CE1 1 ATOM 5292 C CE2 . TYR D 4 182 ? 31.180 -9.833 71.487 1.00 86.11 ? 182 TYR D CE2 1 ATOM 5293 C CZ . TYR D 4 182 ? 29.885 -9.822 70.986 1.00 85.84 ? 182 TYR D CZ 1 ATOM 5294 O OH . TYR D 4 182 ? 29.622 -9.266 69.753 1.00 82.11 ? 182 TYR D OH 1 ATOM 5295 N N . THR D 4 183 ? 29.074 -12.198 77.397 1.00 87.34 ? 183 THR D N 1 ATOM 5296 C CA . THR D 4 183 ? 28.792 -13.129 78.491 1.00 87.01 ? 183 THR D CA 1 ATOM 5297 C C . THR D 4 183 ? 27.743 -14.171 78.053 1.00 86.32 ? 183 THR D C 1 ATOM 5298 O O . THR D 4 183 ? 26.735 -13.829 77.431 1.00 84.78 ? 183 THR D O 1 ATOM 5299 C CB . THR D 4 183 ? 28.364 -12.372 79.772 1.00 85.15 ? 183 THR D CB 1 ATOM 5300 O OG1 . THR D 4 183 ? 27.947 -13.306 80.773 1.00 83.55 ? 183 THR D OG1 1 ATOM 5301 C CG2 . THR D 4 183 ? 27.240 -11.365 79.490 1.00 85.16 ? 183 THR D CG2 1 ATOM 5302 N N . LEU D 4 184 ? 27.996 -15.434 78.393 1.00 88.46 ? 184 LEU D N 1 ATOM 5303 C CA . LEU D 4 184 ? 27.267 -16.579 77.839 1.00 92.04 ? 184 LEU D CA 1 ATOM 5304 C C . LEU D 4 184 ? 27.080 -17.691 78.877 1.00 92.96 ? 184 LEU D C 1 ATOM 5305 O O . LEU D 4 184 ? 27.870 -17.818 79.816 1.00 88.97 ? 184 LEU D O 1 ATOM 5306 C CB . LEU D 4 184 ? 28.042 -17.103 76.624 1.00 93.89 ? 184 LEU D CB 1 ATOM 5307 C CG . LEU D 4 184 ? 27.623 -18.393 75.902 1.00 94.44 ? 184 LEU D CG 1 ATOM 5308 C CD1 . LEU D 4 184 ? 27.856 -18.259 74.402 1.00 94.97 ? 184 LEU D CD1 1 ATOM 5309 C CD2 . LEU D 4 184 ? 28.358 -19.617 76.440 1.00 92.69 ? 184 LEU D CD2 1 ATOM 5310 N N . THR D 4 185 ? 26.030 -18.490 78.697 1.00 95.27 ? 185 THR D N 1 ATOM 5311 C CA . THR D 4 185 ? 25.772 -19.655 79.549 1.00 97.80 ? 185 THR D CA 1 ATOM 5312 C C . THR D 4 185 ? 25.656 -20.941 78.733 1.00 99.62 ? 185 THR D C 1 ATOM 5313 O O . THR D 4 185 ? 25.439 -20.913 77.518 1.00 93.81 ? 185 THR D O 1 ATOM 5314 C CB . THR D 4 185 ? 24.494 -19.470 80.391 1.00 97.43 ? 185 THR D CB 1 ATOM 5315 O OG1 . THR D 4 185 ? 23.409 -19.074 79.543 1.00 95.54 ? 185 THR D OG1 1 ATOM 5316 C CG2 . THR D 4 185 ? 24.712 -18.413 81.460 1.00 97.69 ? 185 THR D CG2 1 ATOM 5317 N N . SER D 4 186 ? 25.821 -22.063 79.429 1.00 107.02 ? 186 SER D N 1 ATOM 5318 C CA . SER D 4 186 ? 25.703 -23.400 78.844 1.00 110.41 ? 186 SER D CA 1 ATOM 5319 C C . SER D 4 186 ? 25.237 -24.394 79.911 1.00 109.65 ? 186 SER D C 1 ATOM 5320 O O . SER D 4 186 ? 25.568 -24.242 81.089 1.00 105.86 ? 186 SER D O 1 ATOM 5321 C CB . SER D 4 186 ? 27.045 -23.836 78.248 1.00 112.84 ? 186 SER D CB 1 ATOM 5322 O OG . SER D 4 186 ? 27.040 -25.206 77.886 1.00 116.42 ? 186 SER D OG 1 ATOM 5323 N N . SER D 4 187 ? 24.481 -25.405 79.487 1.00 110.04 ? 187 SER D N 1 ATOM 5324 C CA . SER D 4 187 ? 23.859 -26.369 80.400 1.00 114.38 ? 187 SER D CA 1 ATOM 5325 C C . SER D 4 187 ? 23.925 -27.800 79.876 1.00 116.34 ? 187 SER D C 1 ATOM 5326 O O . SER D 4 187 ? 24.325 -28.028 78.734 1.00 116.75 ? 187 SER D O 1 ATOM 5327 C CB . SER D 4 187 ? 22.402 -25.981 80.639 1.00 115.94 ? 187 SER D CB 1 ATOM 5328 O OG . SER D 4 187 ? 21.650 -26.045 79.439 1.00 113.64 ? 187 SER D OG 1 ATOM 5329 N N . VAL D 4 188 ? 23.529 -28.753 80.721 1.00 116.14 ? 188 VAL D N 1 ATOM 5330 C CA . VAL D 4 188 ? 23.480 -30.172 80.346 1.00 117.56 ? 188 VAL D CA 1 ATOM 5331 C C . VAL D 4 188 ? 22.543 -30.967 81.268 1.00 119.90 ? 188 VAL D C 1 ATOM 5332 O O . VAL D 4 188 ? 22.516 -30.735 82.479 1.00 119.58 ? 188 VAL D O 1 ATOM 5333 C CB . VAL D 4 188 ? 24.898 -30.805 80.343 1.00 116.02 ? 188 VAL D CB 1 ATOM 5334 C CG1 . VAL D 4 188 ? 25.466 -30.927 81.756 1.00 114.72 ? 188 VAL D CG1 1 ATOM 5335 C CG2 . VAL D 4 188 ? 24.890 -32.157 79.636 1.00 115.24 ? 188 VAL D CG2 1 ATOM 5336 N N . THR D 4 189 ? 21.789 -31.899 80.681 1.00 122.60 ? 189 THR D N 1 ATOM 5337 C CA . THR D 4 189 ? 20.871 -32.772 81.422 1.00 125.85 ? 189 THR D CA 1 ATOM 5338 C C . THR D 4 189 ? 21.464 -34.174 81.573 1.00 131.15 ? 189 THR D C 1 ATOM 5339 O O . THR D 4 189 ? 21.917 -34.766 80.589 1.00 127.98 ? 189 THR D O 1 ATOM 5340 C CB . THR D 4 189 ? 19.508 -32.896 80.712 1.00 124.05 ? 189 THR D CB 1 ATOM 5341 O OG1 . THR D 4 189 ? 19.710 -33.219 79.331 1.00 125.08 ? 189 THR D OG1 1 ATOM 5342 C CG2 . THR D 4 189 ? 18.720 -31.602 80.819 1.00 122.36 ? 189 THR D CG2 1 ATOM 5343 N N . VAL D 4 190 ? 21.442 -34.693 82.803 1.00 140.01 ? 190 VAL D N 1 ATOM 5344 C CA . VAL D 4 190 ? 21.975 -36.025 83.141 1.00 146.52 ? 190 VAL D CA 1 ATOM 5345 C C . VAL D 4 190 ? 20.981 -36.807 84.011 1.00 149.57 ? 190 VAL D C 1 ATOM 5346 O O . VAL D 4 190 ? 19.994 -36.232 84.481 1.00 149.79 ? 190 VAL D O 1 ATOM 5347 C CB . VAL D 4 190 ? 23.339 -35.922 83.880 1.00 148.87 ? 190 VAL D CB 1 ATOM 5348 C CG1 . VAL D 4 190 ? 24.376 -35.264 82.983 1.00 150.49 ? 190 VAL D CG1 1 ATOM 5349 C CG2 . VAL D 4 190 ? 23.228 -35.164 85.204 1.00 148.12 ? 190 VAL D CG2 1 ATOM 5350 N N . PRO D 4 191 ? 21.228 -38.122 84.221 1.00 151.33 ? 191 PRO D N 1 ATOM 5351 C CA . PRO D 4 191 ? 20.494 -38.829 85.278 1.00 149.63 ? 191 PRO D CA 1 ATOM 5352 C C . PRO D 4 191 ? 20.856 -38.279 86.659 1.00 150.72 ? 191 PRO D C 1 ATOM 5353 O O . PRO D 4 191 ? 22.036 -38.047 86.936 1.00 151.92 ? 191 PRO D O 1 ATOM 5354 C CB . PRO D 4 191 ? 20.952 -40.287 85.128 1.00 149.01 ? 191 PRO D CB 1 ATOM 5355 C CG . PRO D 4 191 ? 21.479 -40.393 83.739 1.00 148.99 ? 191 PRO D CG 1 ATOM 5356 C CD . PRO D 4 191 ? 22.054 -39.046 83.420 1.00 150.15 ? 191 PRO D CD 1 ATOM 5357 N N . SER D 4 192 ? 19.852 -38.074 87.511 1.00 150.10 ? 192 SER D N 1 ATOM 5358 C CA . SER D 4 192 ? 20.068 -37.478 88.837 1.00 147.87 ? 192 SER D CA 1 ATOM 5359 C C . SER D 4 192 ? 20.877 -38.367 89.797 1.00 148.79 ? 192 SER D C 1 ATOM 5360 O O . SER D 4 192 ? 21.399 -37.872 90.791 1.00 149.22 ? 192 SER D O 1 ATOM 5361 C CB . SER D 4 192 ? 18.733 -37.083 89.480 1.00 145.36 ? 192 SER D CB 1 ATOM 5362 O OG . SER D 4 192 ? 18.011 -38.217 89.916 1.00 147.97 ? 192 SER D OG 1 ATOM 5363 N N . SER D 4 193 ? 20.955 -39.669 89.513 1.00 146.78 ? 193 SER D N 1 ATOM 5364 C CA . SER D 4 193 ? 21.864 -40.578 90.224 1.00 140.61 ? 193 SER D CA 1 ATOM 5365 C C . SER D 4 193 ? 23.341 -40.330 89.870 1.00 137.28 ? 193 SER D C 1 ATOM 5366 O O . SER D 4 193 ? 24.224 -40.601 90.686 1.00 134.24 ? 193 SER D O 1 ATOM 5367 C CB . SER D 4 193 ? 21.493 -42.039 89.937 1.00 139.02 ? 193 SER D CB 1 ATOM 5368 O OG . SER D 4 193 ? 21.452 -42.298 88.543 1.00 136.08 ? 193 SER D OG 1 ATOM 5369 N N . THR D 4 194 ? 23.598 -39.825 88.661 1.00 133.27 ? 194 THR D N 1 ATOM 5370 C CA . THR D 4 194 ? 24.960 -39.526 88.194 1.00 129.49 ? 194 THR D CA 1 ATOM 5371 C C . THR D 4 194 ? 25.603 -38.337 88.919 1.00 129.62 ? 194 THR D C 1 ATOM 5372 O O . THR D 4 194 ? 26.780 -38.396 89.264 1.00 123.31 ? 194 THR D O 1 ATOM 5373 C CB . THR D 4 194 ? 24.990 -39.245 86.668 1.00 123.72 ? 194 THR D CB 1 ATOM 5374 O OG1 . THR D 4 194 ? 24.254 -40.257 85.971 1.00 119.45 ? 194 THR D OG1 1 ATOM 5375 C CG2 . THR D 4 194 ? 26.417 -39.219 86.133 1.00 121.17 ? 194 THR D CG2 1 ATOM 5376 N N . TRP D 4 195 ? 24.834 -37.271 89.142 1.00 133.51 ? 195 TRP D N 1 ATOM 5377 C CA . TRP D 4 195 ? 25.383 -36.006 89.658 1.00 138.12 ? 195 TRP D CA 1 ATOM 5378 C C . TRP D 4 195 ? 26.050 -36.100 91.045 1.00 144.68 ? 195 TRP D C 1 ATOM 5379 O O . TRP D 4 195 ? 27.111 -35.508 91.244 1.00 144.03 ? 195 TRP D O 1 ATOM 5380 C CB . TRP D 4 195 ? 24.311 -34.909 89.659 1.00 135.60 ? 195 TRP D CB 1 ATOM 5381 N N . PRO D 4 196 ? 25.433 -36.827 92.004 1.00 155.09 ? 196 PRO D N 1 ATOM 5382 C CA . PRO D 4 196 ? 26.104 -37.099 93.288 1.00 159.70 ? 196 PRO D CA 1 ATOM 5383 C C . PRO D 4 196 ? 27.280 -38.079 93.187 1.00 163.57 ? 196 PRO D C 1 ATOM 5384 O O . PRO D 4 196 ? 28.337 -37.827 93.774 1.00 163.47 ? 196 PRO D O 1 ATOM 5385 C CB . PRO D 4 196 ? 24.987 -37.698 94.161 1.00 158.60 ? 196 PRO D CB 1 ATOM 5386 C CG . PRO D 4 196 ? 23.717 -37.274 93.518 1.00 157.74 ? 196 PRO D CG 1 ATOM 5387 C CD . PRO D 4 196 ? 24.014 -37.220 92.051 1.00 156.46 ? 196 PRO D CD 1 ATOM 5388 N N . SER D 4 197 ? 27.086 -39.182 92.459 1.00 164.63 ? 197 SER D N 1 ATOM 5389 C CA . SER D 4 197 ? 28.112 -40.228 92.323 1.00 160.51 ? 197 SER D CA 1 ATOM 5390 C C . SER D 4 197 ? 29.311 -39.756 91.489 1.00 155.72 ? 197 SER D C 1 ATOM 5391 O O . SER D 4 197 ? 30.414 -39.609 92.025 1.00 152.55 ? 197 SER D O 1 ATOM 5392 C CB . SER D 4 197 ? 27.509 -41.509 91.729 1.00 159.90 ? 197 SER D CB 1 ATOM 5393 O OG . SER D 4 197 ? 26.868 -41.251 90.492 1.00 161.12 ? 197 SER D OG 1 ATOM 5394 N N . GLN D 4 198 ? 29.093 -39.515 90.194 1.00 149.32 ? 198 GLN D N 1 ATOM 5395 C CA . GLN D 4 198 ? 30.142 -38.966 89.315 1.00 140.91 ? 198 GLN D CA 1 ATOM 5396 C C . GLN D 4 198 ? 30.412 -37.497 89.642 1.00 139.49 ? 198 GLN D C 1 ATOM 5397 O O . GLN D 4 198 ? 29.505 -36.766 90.050 1.00 138.37 ? 198 GLN D O 1 ATOM 5398 C CB . GLN D 4 198 ? 29.775 -39.088 87.819 1.00 132.80 ? 198 GLN D CB 1 ATOM 5399 C CG . GLN D 4 198 ? 30.352 -40.297 87.091 1.00 124.82 ? 198 GLN D CG 1 ATOM 5400 C CD . GLN D 4 198 ? 29.552 -41.565 87.310 1.00 119.16 ? 198 GLN D CD 1 ATOM 5401 O OE1 . GLN D 4 198 ? 29.107 -41.850 88.421 1.00 114.52 ? 198 GLN D OE1 1 ATOM 5402 N NE2 . GLN D 4 198 ? 29.368 -42.338 86.246 1.00 114.61 ? 198 GLN D NE2 1 ATOM 5403 N N . THR D 4 199 ? 31.664 -37.079 89.463 1.00 137.40 ? 199 THR D N 1 ATOM 5404 C CA . THR D 4 199 ? 32.020 -35.661 89.479 1.00 136.27 ? 199 THR D CA 1 ATOM 5405 C C . THR D 4 199 ? 31.556 -35.053 88.150 1.00 137.15 ? 199 THR D C 1 ATOM 5406 O O . THR D 4 199 ? 31.609 -35.715 87.106 1.00 133.78 ? 199 THR D O 1 ATOM 5407 C CB . THR D 4 199 ? 33.540 -35.446 89.666 1.00 133.24 ? 199 THR D CB 1 ATOM 5408 O OG1 . THR D 4 199 ? 34.009 -36.229 90.771 1.00 130.84 ? 199 THR D OG1 1 ATOM 5409 C CG2 . THR D 4 199 ? 33.863 -33.973 89.923 1.00 130.66 ? 199 THR D CG2 1 ATOM 5410 N N . VAL D 4 200 ? 31.115 -33.796 88.203 1.00 136.32 ? 200 VAL D N 1 ATOM 5411 C CA . VAL D 4 200 ? 30.525 -33.097 87.047 1.00 132.97 ? 200 VAL D CA 1 ATOM 5412 C C . VAL D 4 200 ? 31.348 -31.842 86.734 1.00 126.33 ? 200 VAL D C 1 ATOM 5413 O O . VAL D 4 200 ? 31.650 -31.055 87.634 1.00 120.62 ? 200 VAL D O 1 ATOM 5414 C CB . VAL D 4 200 ? 29.024 -32.752 87.264 1.00 136.42 ? 200 VAL D CB 1 ATOM 5415 C CG1 . VAL D 4 200 ? 28.144 -33.947 86.918 1.00 136.44 ? 200 VAL D CG1 1 ATOM 5416 C CG2 . VAL D 4 200 ? 28.743 -32.289 88.691 1.00 135.87 ? 200 VAL D CG2 1 ATOM 5417 N N . THR D 4 201 ? 31.717 -31.674 85.461 1.00 120.67 ? 201 THR D N 1 ATOM 5418 C CA . THR D 4 201 ? 32.705 -30.668 85.059 1.00 117.20 ? 201 THR D CA 1 ATOM 5419 C C . THR D 4 201 ? 32.578 -30.269 83.582 1.00 118.17 ? 201 THR D C 1 ATOM 5420 O O . THR D 4 201 ? 32.504 -31.132 82.700 1.00 110.25 ? 201 THR D O 1 ATOM 5421 C CB . THR D 4 201 ? 34.138 -31.188 85.339 1.00 115.38 ? 201 THR D CB 1 ATOM 5422 O OG1 . THR D 4 201 ? 34.381 -31.188 86.750 1.00 109.10 ? 201 THR D OG1 1 ATOM 5423 C CG2 . THR D 4 201 ? 35.225 -30.344 84.648 1.00 116.62 ? 201 THR D CG2 1 ATOM 5424 N N . CYS D 4 202 ? 32.572 -28.953 83.339 1.00 122.98 ? 202 CYS D N 1 ATOM 5425 C CA . CYS D 4 202 ? 32.603 -28.368 81.992 1.00 127.60 ? 202 CYS D CA 1 ATOM 5426 C C . CYS D 4 202 ? 33.950 -27.684 81.752 1.00 131.21 ? 202 CYS D C 1 ATOM 5427 O O . CYS D 4 202 ? 34.661 -27.341 82.705 1.00 131.32 ? 202 CYS D O 1 ATOM 5428 C CB . CYS D 4 202 ? 31.460 -27.353 81.808 1.00 129.15 ? 202 CYS D CB 1 ATOM 5429 S SG . CYS D 4 202 ? 31.891 -25.589 81.914 1.00 130.33 ? 202 CYS D SG 1 ATOM 5430 N N . ASN D 4 203 ? 34.288 -27.499 80.474 1.00 132.46 ? 203 ASN D N 1 ATOM 5431 C CA . ASN D 4 203 ? 35.526 -26.820 80.062 1.00 133.19 ? 203 ASN D CA 1 ATOM 5432 C C . ASN D 4 203 ? 35.262 -25.974 78.805 1.00 134.31 ? 203 ASN D C 1 ATOM 5433 O O . ASN D 4 203 ? 34.623 -26.440 77.864 1.00 128.65 ? 203 ASN D O 1 ATOM 5434 C CB . ASN D 4 203 ? 36.672 -27.823 79.808 1.00 135.00 ? 203 ASN D CB 1 ATOM 5435 C CG . ASN D 4 203 ? 36.396 -29.211 80.382 1.00 134.33 ? 203 ASN D CG 1 ATOM 5436 O OD1 . ASN D 4 203 ? 35.457 -29.892 79.965 1.00 133.14 ? 203 ASN D OD1 1 ATOM 5437 N ND2 . ASN D 4 203 ? 37.219 -29.637 81.334 1.00 130.59 ? 203 ASN D ND2 1 ATOM 5438 N N . VAL D 4 204 ? 35.774 -24.743 78.793 1.00 139.45 ? 204 VAL D N 1 ATOM 5439 C CA . VAL D 4 204 ? 35.427 -23.736 77.775 1.00 138.94 ? 204 VAL D CA 1 ATOM 5440 C C . VAL D 4 204 ? 36.668 -23.299 76.989 1.00 137.92 ? 204 VAL D C 1 ATOM 5441 O O . VAL D 4 204 ? 37.783 -23.404 77.499 1.00 144.17 ? 204 VAL D O 1 ATOM 5442 C CB . VAL D 4 204 ? 34.798 -22.493 78.451 1.00 141.96 ? 204 VAL D CB 1 ATOM 5443 C CG1 . VAL D 4 204 ? 34.142 -21.575 77.421 1.00 144.84 ? 204 VAL D CG1 1 ATOM 5444 C CG2 . VAL D 4 204 ? 33.798 -22.914 79.528 1.00 142.27 ? 204 VAL D CG2 1 ATOM 5445 N N . ALA D 4 205 ? 36.471 -22.818 75.757 1.00 130.86 ? 205 ALA D N 1 ATOM 5446 C CA . ALA D 4 205 ? 37.567 -22.288 74.926 1.00 127.55 ? 205 ALA D CA 1 ATOM 5447 C C . ALA D 4 205 ? 37.171 -21.001 74.186 1.00 125.10 ? 205 ALA D C 1 ATOM 5448 O O . ALA D 4 205 ? 36.048 -20.885 73.697 1.00 123.15 ? 205 ALA D O 1 ATOM 5449 C CB . ALA D 4 205 ? 38.045 -23.346 73.940 1.00 126.99 ? 205 ALA D CB 1 ATOM 5450 N N . HIS D 4 206 ? 38.120 -20.063 74.095 1.00 122.16 ? 206 HIS D N 1 ATOM 5451 C CA . HIS D 4 206 ? 37.903 -18.711 73.546 1.00 115.96 ? 206 HIS D CA 1 ATOM 5452 C C . HIS D 4 206 ? 39.057 -18.376 72.572 1.00 114.38 ? 206 HIS D C 1 ATOM 5453 O O . HIS D 4 206 ? 40.207 -18.271 73.004 1.00 112.64 ? 206 HIS D O 1 ATOM 5454 C CB . HIS D 4 206 ? 37.827 -17.708 74.712 1.00 113.17 ? 206 HIS D CB 1 ATOM 5455 C CG . HIS D 4 206 ? 37.853 -16.265 74.302 1.00 110.02 ? 206 HIS D CG 1 ATOM 5456 N ND1 . HIS D 4 206 ? 38.781 -15.374 74.797 1.00 108.55 ? 206 HIS D ND1 1 ATOM 5457 C CD2 . HIS D 4 206 ? 37.061 -15.555 73.464 1.00 106.65 ? 206 HIS D CD2 1 ATOM 5458 C CE1 . HIS D 4 206 ? 38.566 -14.180 74.274 1.00 105.55 ? 206 HIS D CE1 1 ATOM 5459 N NE2 . HIS D 4 206 ? 37.528 -14.263 73.460 1.00 101.21 ? 206 HIS D NE2 1 ATOM 5460 N N . PRO D 4 207 ? 38.756 -18.205 71.261 1.00 112.86 ? 207 PRO D N 1 ATOM 5461 C CA . PRO D 4 207 ? 39.791 -18.165 70.216 1.00 110.22 ? 207 PRO D CA 1 ATOM 5462 C C . PRO D 4 207 ? 40.596 -16.864 70.089 1.00 107.15 ? 207 PRO D C 1 ATOM 5463 O O . PRO D 4 207 ? 41.761 -16.918 69.694 1.00 105.17 ? 207 PRO D O 1 ATOM 5464 C CB . PRO D 4 207 ? 38.984 -18.394 68.937 1.00 110.83 ? 207 PRO D CB 1 ATOM 5465 C CG . PRO D 4 207 ? 37.685 -17.731 69.220 1.00 111.77 ? 207 PRO D CG 1 ATOM 5466 C CD . PRO D 4 207 ? 37.422 -17.936 70.689 1.00 113.11 ? 207 PRO D CD 1 ATOM 5467 N N . GLY D 4 208 ? 39.987 -15.719 70.403 1.00 106.30 ? 208 GLY D N 1 ATOM 5468 C CA . GLY D 4 208 ? 40.643 -14.412 70.267 1.00 103.58 ? 208 GLY D CA 1 ATOM 5469 C C . GLY D 4 208 ? 41.843 -14.185 71.175 1.00 102.15 ? 208 GLY D C 1 ATOM 5470 O O . GLY D 4 208 ? 42.844 -13.606 70.742 1.00 98.82 ? 208 GLY D O 1 ATOM 5471 N N . GLN D 4 209 ? 41.729 -14.627 72.431 1.00 100.82 ? 209 GLN D N 1 ATOM 5472 C CA . GLN D 4 209 ? 42.821 -14.574 73.419 1.00 96.75 ? 209 GLN D CA 1 ATOM 5473 C C . GLN D 4 209 ? 43.458 -15.946 73.702 1.00 93.90 ? 209 GLN D C 1 ATOM 5474 O O . GLN D 4 209 ? 44.336 -16.051 74.558 1.00 90.64 ? 209 GLN D O 1 ATOM 5475 C CB . GLN D 4 209 ? 42.300 -13.986 74.734 1.00 96.29 ? 209 GLN D CB 1 ATOM 5476 N N . GLN D 4 210 ? 43.015 -16.981 72.982 1.00 95.60 ? 210 GLN D N 1 ATOM 5477 C CA . GLN D 4 210 ? 43.444 -18.373 73.187 1.00 97.18 ? 210 GLN D CA 1 ATOM 5478 C C . GLN D 4 210 ? 43.042 -18.962 74.551 1.00 96.94 ? 210 GLN D C 1 ATOM 5479 O O . GLN D 4 210 ? 43.613 -19.963 74.977 1.00 97.09 ? 210 GLN D O 1 ATOM 5480 C CB . GLN D 4 210 ? 44.959 -18.509 72.970 1.00 96.72 ? 210 GLN D CB 1 ATOM 5481 N N . HIS D 4 211 ? 42.035 -18.373 75.199 1.00 99.75 ? 211 HIS D N 1 ATOM 5482 C CA . HIS D 4 211 ? 41.697 -18.694 76.590 1.00 103.55 ? 211 HIS D CA 1 ATOM 5483 C C . HIS D 4 211 ? 41.119 -20.105 76.740 1.00 112.10 ? 211 HIS D C 1 ATOM 5484 O O . HIS D 4 211 ? 40.432 -20.595 75.841 1.00 107.59 ? 211 HIS D O 1 ATOM 5485 C CB . HIS D 4 211 ? 40.713 -17.663 77.150 1.00 99.37 ? 211 HIS D CB 1 ATOM 5486 N N . GLN D 4 212 ? 41.415 -20.739 77.881 1.00 121.01 ? 212 GLN D N 1 ATOM 5487 C CA . GLN D 4 212 ? 41.004 -22.125 78.177 1.00 124.03 ? 212 GLN D CA 1 ATOM 5488 C C . GLN D 4 212 ? 40.926 -22.353 79.696 1.00 128.25 ? 212 GLN D C 1 ATOM 5489 O O . GLN D 4 212 ? 41.791 -21.877 80.436 1.00 128.62 ? 212 GLN D O 1 ATOM 5490 C CB . GLN D 4 212 ? 41.999 -23.110 77.540 1.00 123.62 ? 212 GLN D CB 1 ATOM 5491 C CG . GLN D 4 212 ? 41.725 -24.599 77.771 1.00 123.28 ? 212 GLN D CG 1 ATOM 5492 C CD . GLN D 4 212 ? 40.456 -25.104 77.101 1.00 122.23 ? 212 GLN D CD 1 ATOM 5493 O OE1 . GLN D 4 212 ? 40.088 -24.658 76.015 1.00 119.47 ? 212 GLN D OE1 1 ATOM 5494 N NE2 . GLN D 4 212 ? 39.788 -26.057 77.745 1.00 123.19 ? 212 GLN D NE2 1 ATOM 5495 N N . ARG D 4 213 ? 39.897 -23.078 80.149 1.00 132.71 ? 213 ARG D N 1 ATOM 5496 C CA . ARG D 4 213 ? 39.717 -23.397 81.581 1.00 137.51 ? 213 ARG D CA 1 ATOM 5497 C C . ARG D 4 213 ? 38.731 -24.557 81.803 1.00 137.91 ? 213 ARG D C 1 ATOM 5498 O O . ARG D 4 213 ? 37.898 -24.841 80.941 1.00 126.17 ? 213 ARG D O 1 ATOM 5499 C CB . ARG D 4 213 ? 39.227 -22.157 82.349 1.00 140.91 ? 213 ARG D CB 1 ATOM 5500 C CG . ARG D 4 213 ? 39.638 -22.093 83.821 1.00 139.77 ? 213 ARG D CG 1 ATOM 5501 C CD . ARG D 4 213 ? 38.606 -21.333 84.645 1.00 139.58 ? 213 ARG D CD 1 ATOM 5502 N NE . ARG D 4 213 ? 39.033 -21.075 86.023 1.00 137.54 ? 213 ARG D NE 1 ATOM 5503 C CZ . ARG D 4 213 ? 38.283 -20.484 86.959 1.00 134.01 ? 213 ARG D CZ 1 ATOM 5504 N NH1 . ARG D 4 213 ? 37.040 -20.076 86.695 1.00 131.75 ? 213 ARG D NH1 1 ATOM 5505 N NH2 . ARG D 4 213 ? 38.781 -20.300 88.180 1.00 132.47 ? 213 ARG D NH2 1 ATOM 5506 N N . TRP D 4 214 ? 38.851 -25.211 82.962 1.00 145.57 ? 214 TRP D N 1 ATOM 5507 C CA . TRP D 4 214 ? 37.918 -26.253 83.426 1.00 152.80 ? 214 TRP D CA 1 ATOM 5508 C C . TRP D 4 214 ? 37.385 -25.933 84.834 1.00 155.14 ? 214 TRP D C 1 ATOM 5509 O O . TRP D 4 214 ? 38.096 -25.325 85.639 1.00 158.76 ? 214 TRP D O 1 ATOM 5510 C CB . TRP D 4 214 ? 38.597 -27.635 83.406 1.00 158.54 ? 214 TRP D CB 1 ATOM 5511 C CG . TRP D 4 214 ? 39.920 -27.741 84.158 1.00 164.96 ? 214 TRP D CG 1 ATOM 5512 C CD1 . TRP D 4 214 ? 40.108 -27.702 85.516 1.00 165.11 ? 214 TRP D CD1 1 ATOM 5513 C CD2 . TRP D 4 214 ? 41.224 -27.938 83.583 1.00 167.88 ? 214 TRP D CD2 1 ATOM 5514 N NE1 . TRP D 4 214 ? 41.443 -27.843 85.817 1.00 166.16 ? 214 TRP D NE1 1 ATOM 5515 C CE2 . TRP D 4 214 ? 42.151 -27.992 84.653 1.00 166.85 ? 214 TRP D CE2 1 ATOM 5516 C CE3 . TRP D 4 214 ? 41.701 -28.067 82.268 1.00 165.42 ? 214 TRP D CE3 1 ATOM 5517 C CZ2 . TRP D 4 214 ? 43.529 -28.170 84.447 1.00 163.71 ? 214 TRP D CZ2 1 ATOM 5518 C CZ3 . TRP D 4 214 ? 43.075 -28.243 82.064 1.00 162.57 ? 214 TRP D CZ3 1 ATOM 5519 C CH2 . TRP D 4 214 ? 43.969 -28.293 83.151 1.00 161.49 ? 214 TRP D CH2 1 ATOM 5520 N N . THR D 4 215 ? 36.139 -26.334 85.120 1.00 153.47 ? 215 THR D N 1 ATOM 5521 C CA . THR D 4 215 ? 35.501 -26.097 86.435 1.00 150.47 ? 215 THR D CA 1 ATOM 5522 C C . THR D 4 215 ? 34.616 -27.275 86.862 1.00 147.39 ? 215 THR D C 1 ATOM 5523 O O . THR D 4 215 ? 33.828 -27.773 86.063 1.00 144.33 ? 215 THR D O 1 ATOM 5524 C CB . THR D 4 215 ? 34.612 -24.827 86.430 1.00 147.54 ? 215 THR D CB 1 ATOM 5525 O OG1 . THR D 4 215 ? 35.310 -23.736 85.819 1.00 150.80 ? 215 THR D OG1 1 ATOM 5526 C CG2 . THR D 4 215 ? 34.210 -24.428 87.855 1.00 143.59 ? 215 THR D CG2 1 ATOM 5527 N N . ARG D 4 216 ? 34.739 -27.688 88.126 1.00 145.89 ? 216 ARG D N 1 ATOM 5528 C CA . ARG D 4 216 ? 33.891 -28.731 88.719 1.00 144.92 ? 216 ARG D CA 1 ATOM 5529 C C . ARG D 4 216 ? 32.858 -28.124 89.668 1.00 145.99 ? 216 ARG D C 1 ATOM 5530 O O . ARG D 4 216 ? 33.086 -27.053 90.242 1.00 145.30 ? 216 ARG D O 1 ATOM 5531 C CB . ARG D 4 216 ? 34.748 -29.749 89.471 1.00 144.00 ? 216 ARG D CB 1 ATOM 5532 N N . LYS D 4 217 ? 31.737 -28.826 89.844 1.00 144.06 ? 217 LYS D N 1 ATOM 5533 C CA . LYS D 4 217 ? 30.603 -28.307 90.620 1.00 142.03 ? 217 LYS D CA 1 ATOM 5534 C C . LYS D 4 217 ? 30.812 -28.518 92.114 1.00 133.21 ? 217 LYS D C 1 ATOM 5535 O O . LYS D 4 217 ? 31.163 -29.617 92.544 1.00 130.43 ? 217 LYS D O 1 ATOM 5536 C CB . LYS D 4 217 ? 29.281 -28.962 90.196 1.00 147.54 ? 217 LYS D CB 1 ATOM 5537 C CG . LYS D 4 217 ? 28.986 -28.946 88.700 1.00 154.52 ? 217 LYS D CG 1 ATOM 5538 C CD . LYS D 4 217 ? 28.905 -27.545 88.104 1.00 159.66 ? 217 LYS D CD 1 ATOM 5539 C CE . LYS D 4 217 ? 29.248 -27.554 86.620 1.00 164.90 ? 217 LYS D CE 1 ATOM 5540 N NZ . LYS D 4 217 ? 29.446 -26.181 86.082 1.00 167.39 ? 217 LYS D NZ 1 ATOM 5541 N N . LEU D 4 218 ? 30.570 -27.462 92.890 1.00 127.10 ? 218 LEU D N 1 ATOM 5542 C CA . LEU D 4 218 ? 30.755 -27.466 94.343 1.00 122.55 ? 218 LEU D CA 1 ATOM 5543 C C . LEU D 4 218 ? 29.393 -27.595 95.041 1.00 114.60 ? 218 LEU D C 1 ATOM 5544 O O . LEU D 4 218 ? 29.003 -26.743 95.848 1.00 112.66 ? 218 LEU D O 1 ATOM 5545 C CB . LEU D 4 218 ? 31.484 -26.185 94.783 1.00 123.64 ? 218 LEU D CB 1 ATOM 5546 C CG . LEU D 4 218 ? 32.732 -25.773 93.990 1.00 123.85 ? 218 LEU D CG 1 ATOM 5547 C CD1 . LEU D 4 218 ? 33.361 -24.535 94.612 1.00 122.77 ? 218 LEU D CD1 1 ATOM 5548 C CD2 . LEU D 4 218 ? 33.747 -26.904 93.902 1.00 124.00 ? 218 LEU D CD2 1 ATOM 5549 N N . CYS D 4 219 ? 28.683 -28.678 94.725 1.00 104.80 ? 219 CYS D N 1 ATOM 5550 C CA . CYS D 4 219 ? 27.331 -28.910 95.238 1.00 101.57 ? 219 CYS D CA 1 ATOM 5551 C C . CYS D 4 219 ? 27.354 -29.339 96.698 1.00 97.77 ? 219 CYS D C 1 ATOM 5552 O O . CYS D 4 219 ? 27.036 -28.546 97.583 1.00 95.20 ? 219 CYS D O 1 ATOM 5553 C CB . CYS D 4 219 ? 26.600 -29.956 94.386 1.00 101.62 ? 219 CYS D CB 1 ATOM 5554 S SG . CYS D 4 219 ? 27.644 -31.306 93.784 1.00 101.46 ? 219 CYS D SG 1 HETATM 5555 C C1 . NAG E 5 . ? 19.389 -7.524 -10.734 1.00 42.66 ? 301 NAG B C1 1 HETATM 5556 C C2 . NAG E 5 . ? 17.879 -7.320 -10.758 1.00 42.58 ? 301 NAG B C2 1 HETATM 5557 C C3 . NAG E 5 . ? 17.289 -7.897 -9.477 1.00 42.21 ? 301 NAG B C3 1 HETATM 5558 C C4 . NAG E 5 . ? 17.700 -9.349 -9.268 1.00 42.75 ? 301 NAG B C4 1 HETATM 5559 C C5 . NAG E 5 . ? 19.221 -9.426 -9.321 1.00 43.91 ? 301 NAG B C5 1 HETATM 5560 C C6 . NAG E 5 . ? 19.802 -10.815 -9.090 1.00 45.09 ? 301 NAG B C6 1 HETATM 5561 C C7 . NAG E 5 . ? 17.304 -5.293 -12.041 1.00 43.49 ? 301 NAG B C7 1 HETATM 5562 C C8 . NAG E 5 . ? 16.940 -3.839 -11.947 1.00 42.46 ? 301 NAG B C8 1 HETATM 5563 N N2 . NAG E 5 . ? 17.522 -5.914 -10.871 1.00 42.91 ? 301 NAG B N2 1 HETATM 5564 O O3 . NAG E 5 . ? 15.875 -7.772 -9.543 1.00 42.47 ? 301 NAG B O3 1 HETATM 5565 O O4 . NAG E 5 . ? 17.291 -9.797 -7.978 1.00 44.30 ? 301 NAG B O4 1 HETATM 5566 O O5 . NAG E 5 . ? 19.649 -8.928 -10.592 1.00 43.04 ? 301 NAG B O5 1 HETATM 5567 O O6 . NAG E 5 . ? 19.297 -11.720 -10.073 1.00 48.10 ? 301 NAG B O6 1 HETATM 5568 O O7 . NAG E 5 . ? 17.385 -5.842 -13.130 1.00 43.96 ? 301 NAG B O7 1 HETATM 5569 C C1 . NAG F 5 . ? 15.922 -10.225 -7.877 1.00 45.78 ? 302 NAG B C1 1 HETATM 5570 C C2 . NAG F 5 . ? 15.823 -11.308 -6.800 1.00 46.59 ? 302 NAG B C2 1 HETATM 5571 C C3 . NAG F 5 . ? 14.388 -11.713 -6.483 1.00 48.12 ? 302 NAG B C3 1 HETATM 5572 C C4 . NAG F 5 . ? 13.533 -10.479 -6.218 1.00 49.03 ? 302 NAG B C4 1 HETATM 5573 C C5 . NAG F 5 . ? 13.731 -9.410 -7.290 1.00 47.97 ? 302 NAG B C5 1 HETATM 5574 C C6 . NAG F 5 . ? 13.037 -8.114 -6.909 1.00 47.07 ? 302 NAG B C6 1 HETATM 5575 C C7 . NAG F 5 . ? 17.790 -12.728 -6.598 1.00 42.22 ? 302 NAG B C7 1 HETATM 5576 C C8 . NAG F 5 . ? 18.498 -13.976 -7.032 1.00 41.98 ? 302 NAG B C8 1 HETATM 5577 N N2 . NAG F 5 . ? 16.601 -12.487 -7.148 1.00 43.75 ? 302 NAG B N2 1 HETATM 5578 O O3 . NAG F 5 . ? 14.405 -12.545 -5.319 1.00 46.89 ? 302 NAG B O3 1 HETATM 5579 O O4 . NAG F 5 . ? 12.154 -10.862 -6.218 1.00 52.58 ? 302 NAG B O4 1 HETATM 5580 O O5 . NAG F 5 . ? 15.115 -9.114 -7.500 1.00 46.97 ? 302 NAG B O5 1 HETATM 5581 O O6 . NAG F 5 . ? 13.093 -7.244 -8.042 1.00 45.65 ? 302 NAG B O6 1 HETATM 5582 O O7 . NAG F 5 . ? 18.292 -11.979 -5.781 1.00 41.71 ? 302 NAG B O7 1 HETATM 5583 C C1 . BMA G 6 . ? 11.567 -10.779 -4.914 1.00 57.68 ? 303 BMA B C1 1 HETATM 5584 C C2 . BMA G 6 . ? 10.068 -10.894 -5.093 1.00 62.21 ? 303 BMA B C2 1 HETATM 5585 C C3 . BMA G 6 . ? 9.345 -10.905 -3.748 1.00 66.37 ? 303 BMA B C3 1 HETATM 5586 C C4 . BMA G 6 . ? 9.965 -11.927 -2.799 1.00 64.99 ? 303 BMA B C4 1 HETATM 5587 C C5 . BMA G 6 . ? 11.491 -11.835 -2.757 1.00 62.81 ? 303 BMA B C5 1 HETATM 5588 C C6 . BMA G 6 . ? 12.118 -12.992 -1.971 1.00 63.38 ? 303 BMA B C6 1 HETATM 5589 O O2 . BMA G 6 . ? 9.813 -12.096 -5.831 1.00 62.59 ? 303 BMA B O2 1 HETATM 5590 O O3 . BMA G 6 . ? 7.972 -11.278 -3.948 1.00 74.84 ? 303 BMA B O3 1 HETATM 5591 O O4 . BMA G 6 . ? 9.440 -11.731 -1.482 1.00 63.50 ? 303 BMA B O4 1 HETATM 5592 O O5 . BMA G 6 . ? 12.035 -11.831 -4.081 1.00 58.70 ? 303 BMA B O5 1 HETATM 5593 O O6 . BMA G 6 . ? 11.895 -14.213 -2.691 1.00 64.56 ? 303 BMA B O6 1 HETATM 5594 C C1 . MAN H 7 . ? 7.047 -10.179 -3.839 1.00 87.02 ? 304 MAN B C1 1 HETATM 5595 C C2 . MAN H 7 . ? 5.613 -10.711 -3.806 1.00 91.67 ? 304 MAN B C2 1 HETATM 5596 C C3 . MAN H 7 . ? 5.339 -11.463 -5.107 1.00 89.55 ? 304 MAN B C3 1 HETATM 5597 C C4 . MAN H 7 . ? 5.523 -10.523 -6.298 1.00 88.70 ? 304 MAN B C4 1 HETATM 5598 C C5 . MAN H 7 . ? 6.807 -9.685 -6.230 1.00 90.94 ? 304 MAN B C5 1 HETATM 5599 C C6 . MAN H 7 . ? 6.687 -8.461 -7.140 1.00 92.49 ? 304 MAN B C6 1 HETATM 5600 O O2 . MAN H 7 . ? 4.634 -9.659 -3.718 1.00 101.04 ? 304 MAN B O2 1 HETATM 5601 O O3 . MAN H 7 . ? 4.012 -12.004 -5.112 1.00 86.98 ? 304 MAN B O3 1 HETATM 5602 O O4 . MAN H 7 . ? 5.568 -11.303 -7.493 1.00 88.49 ? 304 MAN B O4 1 HETATM 5603 O O5 . MAN H 7 . ? 7.153 -9.229 -4.907 1.00 91.44 ? 304 MAN B O5 1 HETATM 5604 O O6 . MAN H 7 . ? 6.667 -8.868 -8.513 1.00 94.45 ? 304 MAN B O6 1 HETATM 5605 C C1 . MAN I 7 . ? 4.699 -8.830 -2.539 1.00 109.63 ? 305 MAN B C1 1 HETATM 5606 C C2 . MAN I 7 . ? 3.308 -8.274 -2.264 1.00 114.91 ? 305 MAN B C2 1 HETATM 5607 C C3 . MAN I 7 . ? 2.881 -7.317 -3.385 1.00 114.68 ? 305 MAN B C3 1 HETATM 5608 C C4 . MAN I 7 . ? 3.955 -6.269 -3.712 1.00 111.31 ? 305 MAN B C4 1 HETATM 5609 C C5 . MAN I 7 . ? 5.364 -6.857 -3.765 1.00 108.37 ? 305 MAN B C5 1 HETATM 5610 C C6 . MAN I 7 . ? 6.433 -5.769 -3.773 1.00 106.99 ? 305 MAN B C6 1 HETATM 5611 O O2 . MAN I 7 . ? 3.342 -7.569 -1.013 1.00 123.33 ? 305 MAN B O2 1 HETATM 5612 O O3 . MAN I 7 . ? 1.658 -6.661 -3.019 1.00 114.56 ? 305 MAN B O3 1 HETATM 5613 O O4 . MAN I 7 . ? 3.673 -5.679 -4.988 1.00 107.66 ? 305 MAN B O4 1 HETATM 5614 O O5 . MAN I 7 . ? 5.607 -7.728 -2.652 1.00 109.40 ? 305 MAN B O5 1 HETATM 5615 O O6 . MAN I 7 . ? 7.731 -6.374 -3.747 1.00 103.37 ? 305 MAN B O6 1 HETATM 5616 C C1 . MAN J 7 . ? 2.625 -8.192 0.077 1.00 130.07 ? 306 MAN B C1 1 HETATM 5617 C C2 . MAN J 7 . ? 2.186 -7.079 1.019 1.00 133.11 ? 306 MAN B C2 1 HETATM 5618 C C3 . MAN J 7 . ? 3.412 -6.393 1.621 1.00 132.15 ? 306 MAN B C3 1 HETATM 5619 C C4 . MAN J 7 . ? 4.390 -7.392 2.242 1.00 130.88 ? 306 MAN B C4 1 HETATM 5620 C C5 . MAN J 7 . ? 4.606 -8.665 1.414 1.00 129.92 ? 306 MAN B C5 1 HETATM 5621 C C6 . MAN J 7 . ? 5.215 -9.751 2.304 1.00 123.90 ? 306 MAN B C6 1 HETATM 5622 O O2 . MAN J 7 . ? 1.350 -7.625 2.048 1.00 134.61 ? 306 MAN B O2 1 HETATM 5623 O O3 . MAN J 7 . ? 2.994 -5.451 2.615 1.00 133.48 ? 306 MAN B O3 1 HETATM 5624 O O4 . MAN J 7 . ? 5.654 -6.739 2.399 1.00 130.51 ? 306 MAN B O4 1 HETATM 5625 O O5 . MAN J 7 . ? 3.387 -9.151 0.824 1.00 133.58 ? 306 MAN B O5 1 HETATM 5626 O O6 . MAN J 7 . ? 5.684 -10.858 1.525 1.00 118.49 ? 306 MAN B O6 1 HETATM 5627 C C1 . MAN K 7 . ? 12.147 -15.393 -1.912 1.00 66.83 ? 307 MAN B C1 1 HETATM 5628 C C2 . MAN K 7 . ? 12.067 -16.600 -2.844 1.00 68.59 ? 307 MAN B C2 1 HETATM 5629 C C3 . MAN K 7 . ? 10.626 -16.816 -3.298 1.00 70.88 ? 307 MAN B C3 1 HETATM 5630 C C4 . MAN K 7 . ? 9.719 -16.945 -2.072 1.00 72.75 ? 307 MAN B C4 1 HETATM 5631 C C5 . MAN K 7 . ? 9.863 -15.670 -1.231 1.00 75.00 ? 307 MAN B C5 1 HETATM 5632 C C6 . MAN K 7 . ? 8.941 -15.580 -0.011 1.00 79.62 ? 307 MAN B C6 1 HETATM 5633 O O2 . MAN K 7 . ? 12.582 -17.764 -2.184 1.00 66.14 ? 307 MAN B O2 1 HETATM 5634 O O3 . MAN K 7 . ? 10.540 -17.968 -4.158 1.00 71.11 ? 307 MAN B O3 1 HETATM 5635 O O4 . MAN K 7 . ? 8.368 -17.159 -2.501 1.00 73.37 ? 307 MAN B O4 1 HETATM 5636 O O5 . MAN K 7 . ? 11.236 -15.558 -0.824 1.00 71.08 ? 307 MAN B O5 1 HETATM 5637 O O6 . MAN K 7 . ? 9.587 -16.089 1.166 1.00 85.30 ? 307 MAN B O6 1 HETATM 5638 C C1 . MAN L 7 . ? 8.847 -15.811 2.376 1.00 89.53 ? 308 MAN B C1 1 HETATM 5639 C C2 . MAN L 7 . ? 9.556 -16.549 3.510 1.00 91.32 ? 308 MAN B C2 1 HETATM 5640 C C3 . MAN L 7 . ? 9.360 -18.067 3.364 1.00 91.53 ? 308 MAN B C3 1 HETATM 5641 C C4 . MAN L 7 . ? 7.889 -18.456 3.190 1.00 91.40 ? 308 MAN B C4 1 HETATM 5642 C C5 . MAN L 7 . ? 7.196 -17.596 2.122 1.00 89.32 ? 308 MAN B C5 1 HETATM 5643 C C6 . MAN L 7 . ? 5.678 -17.819 2.100 1.00 85.97 ? 308 MAN B C6 1 HETATM 5644 O O2 . MAN L 7 . ? 9.088 -16.067 4.779 1.00 91.08 ? 308 MAN B O2 1 HETATM 5645 O O3 . MAN L 7 . ? 9.906 -18.752 4.498 1.00 91.65 ? 308 MAN B O3 1 HETATM 5646 O O4 . MAN L 7 . ? 7.813 -19.851 2.843 1.00 88.56 ? 308 MAN B O4 1 HETATM 5647 O O5 . MAN L 7 . ? 7.462 -16.194 2.340 1.00 91.63 ? 308 MAN B O5 1 HETATM 5648 O O6 . MAN L 7 . ? 5.189 -17.918 0.755 1.00 81.41 ? 308 MAN B O6 1 HETATM 5649 C C1 . MAN M 7 . ? 10.563 -17.661 -5.577 1.00 70.80 ? 309 MAN B C1 1 HETATM 5650 C C2 . MAN M 7 . ? 9.870 -18.781 -6.341 1.00 70.49 ? 309 MAN B C2 1 HETATM 5651 C C3 . MAN M 7 . ? 10.646 -20.088 -6.213 1.00 70.72 ? 309 MAN B C3 1 HETATM 5652 C C4 . MAN M 7 . ? 12.096 -19.909 -6.657 1.00 72.89 ? 309 MAN B C4 1 HETATM 5653 C C5 . MAN M 7 . ? 12.733 -18.652 -6.052 1.00 75.57 ? 309 MAN B C5 1 HETATM 5654 C C6 . MAN M 7 . ? 14.054 -18.359 -6.761 1.00 78.64 ? 309 MAN B C6 1 HETATM 5655 O O2 . MAN M 7 . ? 9.782 -18.403 -7.718 1.00 70.62 ? 309 MAN B O2 1 HETATM 5656 O O3 . MAN M 7 . ? 10.016 -21.102 -6.999 1.00 68.36 ? 309 MAN B O3 1 HETATM 5657 O O4 . MAN M 7 . ? 12.854 -21.065 -6.268 1.00 71.70 ? 309 MAN B O4 1 HETATM 5658 O O5 . MAN M 7 . ? 11.875 -17.498 -6.132 1.00 73.19 ? 309 MAN B O5 1 HETATM 5659 O O6 . MAN M 7 . ? 14.590 -17.099 -6.335 1.00 81.89 ? 309 MAN B O6 1 HETATM 5660 O O . HOH N 8 . ? 23.542 -27.319 -8.327 1.00 34.19 ? 101 HOH A O 1 HETATM 5661 O O . HOH N 8 . ? 15.016 -23.644 -5.471 1.00 36.11 ? 102 HOH A O 1 HETATM 5662 O O . HOH N 8 . ? 7.311 -31.761 0.223 1.00 49.69 ? 103 HOH A O 1 HETATM 5663 O O . HOH O 8 . ? 23.417 -16.961 17.045 1.00 29.02 ? 401 HOH B O 1 HETATM 5664 O O . HOH O 8 . ? 42.354 -15.105 12.515 1.00 36.42 ? 402 HOH B O 1 HETATM 5665 O O . HOH O 8 . ? 37.105 -24.792 27.943 1.00 37.98 ? 403 HOH B O 1 HETATM 5666 O O . HOH O 8 . ? 30.581 -0.429 3.114 1.00 43.17 ? 404 HOH B O 1 HETATM 5667 O O . HOH O 8 . ? 41.797 -14.240 36.051 1.00 49.33 ? 405 HOH B O 1 HETATM 5668 O O . HOH O 8 . ? 32.248 -25.131 9.994 1.00 50.47 ? 406 HOH B O 1 HETATM 5669 O O . HOH O 8 . ? 34.536 -23.652 25.653 1.00 33.76 ? 407 HOH B O 1 HETATM 5670 O O . HOH O 8 . ? 33.030 -20.690 28.780 1.00 28.72 ? 408 HOH B O 1 HETATM 5671 O O . HOH O 8 . ? 31.587 -19.923 17.167 1.00 48.84 ? 409 HOH B O 1 HETATM 5672 O O . HOH O 8 . ? 37.786 -4.885 3.140 1.00 45.49 ? 410 HOH B O 1 HETATM 5673 O O . HOH O 8 . ? 17.113 -29.101 -0.994 1.00 45.70 ? 411 HOH B O 1 HETATM 5674 O O . HOH O 8 . ? 34.083 2.198 -6.084 1.00 33.90 ? 412 HOH B O 1 HETATM 5675 O O . HOH O 8 . ? 19.478 -9.582 -5.393 1.00 36.77 ? 413 HOH B O 1 HETATM 5676 O O . HOH O 8 . ? 37.055 -9.356 11.672 1.00 45.41 ? 414 HOH B O 1 HETATM 5677 O O . HOH O 8 . ? 29.358 -30.108 12.251 1.00 41.94 ? 415 HOH B O 1 HETATM 5678 O O . HOH O 8 . ? 36.687 4.385 -5.997 1.00 34.71 ? 416 HOH B O 1 HETATM 5679 O O . HOH O 8 . ? 32.071 -8.028 -7.782 1.00 51.89 ? 417 HOH B O 1 HETATM 5680 O O . HOH O 8 . ? 36.126 2.650 -7.953 1.00 33.28 ? 418 HOH B O 1 HETATM 5681 O O . HOH O 8 . ? 18.286 -18.074 -5.886 1.00 34.90 ? 419 HOH B O 1 HETATM 5682 O O . HOH O 8 . ? 37.037 -5.444 28.020 1.00 38.49 ? 420 HOH B O 1 HETATM 5683 O O . HOH O 8 . ? 28.176 -12.711 -10.314 1.00 43.66 ? 421 HOH B O 1 HETATM 5684 O O . HOH O 8 . ? 13.807 -15.199 7.404 1.00 38.88 ? 422 HOH B O 1 HETATM 5685 O O . HOH O 8 . ? 28.070 0.598 -17.076 1.00 57.31 ? 423 HOH B O 1 HETATM 5686 O O . HOH O 8 . ? 40.519 -6.859 -18.368 1.00 42.41 ? 424 HOH B O 1 HETATM 5687 O O . HOH O 8 . ? 34.305 -24.791 11.778 1.00 34.32 ? 425 HOH B O 1 HETATM 5688 O O . HOH O 8 . ? 27.879 -5.951 16.101 1.00 57.09 ? 426 HOH B O 1 HETATM 5689 O O . HOH O 8 . ? 35.145 -7.296 13.705 1.00 35.42 ? 427 HOH B O 1 HETATM 5690 O O . HOH P 8 . ? 19.605 -27.971 61.214 1.00 44.83 ? 301 HOH C O 1 HETATM 5691 O O . HOH P 8 . ? 20.817 -33.656 39.096 1.00 40.44 ? 302 HOH C O 1 HETATM 5692 O O . HOH P 8 . ? 21.543 -25.403 31.998 1.00 54.36 ? 303 HOH C O 1 HETATM 5693 O O . HOH P 8 . ? 16.705 -23.144 40.745 1.00 35.22 ? 304 HOH C O 1 HETATM 5694 O O . HOH P 8 . ? 28.519 -23.317 30.150 1.00 47.40 ? 305 HOH C O 1 HETATM 5695 O O . HOH P 8 . ? 26.220 -28.091 56.962 1.00 49.68 ? 306 HOH C O 1 HETATM 5696 O O . HOH P 8 . ? 14.156 -7.269 82.385 1.00 59.87 ? 307 HOH C O 1 HETATM 5697 O O . HOH P 8 . ? 22.315 -32.440 63.343 1.00 52.75 ? 308 HOH C O 1 HETATM 5698 O O . HOH Q 8 . ? 34.223 -16.844 34.121 1.00 38.79 ? 301 HOH D O 1 HETATM 5699 O O . HOH Q 8 . ? 31.985 -17.738 37.174 1.00 41.47 ? 302 HOH D O 1 HETATM 5700 O O . HOH Q 8 . ? 48.417 -5.281 47.478 1.00 48.68 ? 303 HOH D O 1 HETATM 5701 O O . HOH Q 8 . ? 48.601 -9.869 43.974 1.00 50.50 ? 304 HOH D O 1 HETATM 5702 O O . HOH Q 8 . ? 38.668 -24.856 40.033 1.00 37.76 ? 305 HOH D O 1 HETATM 5703 O O . HOH Q 8 . ? 37.502 -22.167 34.466 1.00 42.50 ? 306 HOH D O 1 HETATM 5704 O O . HOH Q 8 . ? 26.234 -10.063 47.163 1.00 47.07 ? 307 HOH D O 1 HETATM 5705 O O . HOH Q 8 . ? 38.797 -27.191 38.698 1.00 37.23 ? 308 HOH D O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ILE 1 1 1 ILE ILE A . n A 1 2 VAL 2 2 2 VAL VAL A . n A 1 3 CYS 3 3 3 CYS CYS A . n A 1 4 HIS 4 4 4 HIS HIS A . n A 1 5 THR 5 5 5 THR THR A . n A 1 6 THR 6 6 6 THR THR A . n A 1 7 ALA 7 7 7 ALA ALA A . n A 1 8 THR 8 8 8 THR THR A . n A 1 9 SER 9 9 9 SER SER A . n A 1 10 PRO 10 10 10 PRO PRO A . n A 1 11 ILE 11 11 11 ILE ILE A . n A 1 12 SER 12 12 12 SER SER A . n A 1 13 ALA 13 13 13 ALA ALA A . n A 1 14 VAL 14 14 14 VAL VAL A . n A 1 15 THR 15 15 15 THR THR A . n A 1 16 CYS 16 16 16 CYS CYS A . n A 1 17 PRO 17 17 17 PRO PRO A . n A 1 18 PRO 18 18 18 PRO PRO A . n A 1 19 GLY 19 19 19 GLY GLY A . n A 1 20 GLU 20 20 20 GLU GLU A . n A 1 21 ASN 21 21 21 ASN ASN A . n A 1 22 LEU 22 22 22 LEU LEU A . n A 1 23 CYS 23 23 23 CYS CYS A . n A 1 24 TYR 24 24 24 TYR TYR A . n A 1 25 ARG 25 25 25 ARG ARG A . n A 1 26 LYS 26 26 26 LYS LYS A . n A 1 27 MET 27 27 27 MET MET A . n A 1 28 TRP 28 28 28 TRP TRP A . n A 1 29 CYS 29 29 29 CYS CYS A . n A 1 30 ASP 30 30 30 ASP ASP A . n A 1 31 VAL 31 31 31 VAL VAL A . n A 1 32 PHE 32 32 32 PHE PHE A . n A 1 33 CYS 33 33 33 CYS CYS A . n A 1 34 SER 34 34 34 SER SER A . n A 1 35 SER 35 35 35 SER SER A . n A 1 36 ARG 36 36 36 ARG ARG A . n A 1 37 GLY 37 37 37 GLY GLY A . n A 1 38 LYS 38 38 38 LYS LYS A . n A 1 39 VAL 39 39 39 VAL VAL A . n A 1 40 VAL 40 40 40 VAL VAL A . n A 1 41 GLU 41 41 41 GLU GLU A . n A 1 42 LEU 42 42 42 LEU LEU A . n A 1 43 GLY 43 43 43 GLY GLY A . n A 1 44 CYS 44 44 44 CYS CYS A . n A 1 45 ALA 45 45 45 ALA ALA A . n A 1 46 ALA 46 46 46 ALA ALA A . n A 1 47 THR 47 47 47 THR THR A . n A 1 48 CYS 48 48 48 CYS CYS A . n A 1 49 PRO 49 49 49 PRO PRO A . n A 1 50 SER 50 50 50 SER SER A . n A 1 51 LYS 51 51 51 LYS LYS A . n A 1 52 LYS 52 52 52 LYS LYS A . n A 1 53 PRO 53 53 53 PRO PRO A . n A 1 54 TYR 54 54 54 TYR TYR A . n A 1 55 GLU 55 55 55 GLU GLU A . n A 1 56 GLU 56 56 56 GLU GLU A . n A 1 57 VAL 57 57 57 VAL VAL A . n A 1 58 THR 58 58 58 THR THR A . n A 1 59 CYS 59 59 59 CYS CYS A . n A 1 60 CYS 60 60 60 CYS CYS A . n A 1 61 SER 61 61 61 SER SER A . n A 1 62 THR 62 62 62 THR THR A . n A 1 63 ASP 63 63 63 ASP ASP A . n A 1 64 LYS 64 64 64 LYS LYS A . n A 1 65 CYS 65 65 65 CYS CYS A . n A 1 66 ASN 66 66 66 ASN ASN A . n A 1 67 PRO 67 67 67 PRO PRO A . n A 1 68 HIS 68 68 68 HIS HIS A . n A 1 69 PRO 69 69 69 PRO PRO A . n A 1 70 LYS 70 70 70 LYS LYS A . n A 1 71 GLN 71 71 71 GLN GLN A . n A 1 72 ARG 72 72 72 ARG ARG A . n A 1 73 PRO 73 73 73 PRO PRO A . n A 1 74 GLY 74 74 74 GLY GLY A . n B 2 1 LYS 1 0 0 LYS LYS B . n B 2 2 SER 2 1 1 SER SER B . n B 2 3 GLU 3 2 2 GLU GLU B . n B 2 4 HIS 4 3 3 HIS HIS B . n B 2 5 GLU 5 4 4 GLU GLU B . n B 2 6 THR 6 5 5 THR THR B . n B 2 7 ARG 7 6 6 ARG ARG B . n B 2 8 LEU 8 7 7 LEU LEU B . n B 2 9 GLU 9 8 8 GLU GLU B . n B 2 10 ALA 10 9 9 ALA ALA B . n B 2 11 LYS 11 10 10 LYS LYS B . n B 2 12 LEU 12 11 11 LEU LEU B . n B 2 13 PHE 13 12 12 PHE PHE B . n B 2 14 GLU 14 13 13 GLU GLU B . n B 2 15 ASP 15 14 14 ASP ASP B . n B 2 16 TYR 16 15 15 TYR TYR B . n B 2 17 SER 17 16 16 SER SER B . n B 2 18 SER 18 17 17 SER SER B . n B 2 19 VAL 19 18 18 VAL VAL B . n B 2 20 VAL 20 19 19 VAL VAL B . n B 2 21 ARG 21 20 20 ARG ARG B . n B 2 22 PRO 22 21 21 PRO PRO B . n B 2 23 VAL 23 22 22 VAL VAL B . n B 2 24 GLU 24 23 23 GLU GLU B . n B 2 25 ASP 25 24 24 ASP ASP B . n B 2 26 HIS 26 25 25 HIS HIS B . n B 2 27 ARG 27 26 26 ARG ARG B . n B 2 28 GLU 28 27 27 GLU GLU B . n B 2 29 ILE 29 28 28 ILE ILE B . n B 2 30 VAL 30 29 29 VAL VAL B . n B 2 31 GLN 31 30 30 GLN GLN B . n B 2 32 VAL 32 31 31 VAL VAL B . n B 2 33 THR 33 32 32 THR THR B . n B 2 34 VAL 34 33 33 VAL VAL B . n B 2 35 GLY 35 34 34 GLY GLY B . n B 2 36 LEU 36 35 35 LEU LEU B . n B 2 37 GLN 37 36 36 GLN GLN B . n B 2 38 LEU 38 37 37 LEU LEU B . n B 2 39 ILE 39 38 38 ILE ILE B . n B 2 40 GLN 40 39 39 GLN GLN B . n B 2 41 LEU 41 40 40 LEU LEU B . n B 2 42 ILE 42 41 41 ILE ILE B . n B 2 43 ASN 43 42 42 ASN ASN B . n B 2 44 VAL 44 43 43 VAL VAL B . n B 2 45 ASP 45 44 44 ASP ASP B . n B 2 46 GLU 46 45 45 GLU GLU B . n B 2 47 VAL 47 46 46 VAL VAL B . n B 2 48 ASN 48 47 47 ASN ASN B . n B 2 49 GLN 49 48 48 GLN GLN B . n B 2 50 ILE 50 49 49 ILE ILE B . n B 2 51 VAL 51 50 50 VAL VAL B . n B 2 52 THR 52 51 51 THR THR B . n B 2 53 THR 53 52 52 THR THR B . n B 2 54 ASN 54 53 53 ASN ASN B . n B 2 55 VAL 55 54 54 VAL VAL B . n B 2 56 ARG 56 55 55 ARG ARG B . n B 2 57 LEU 57 56 56 LEU LEU B . n B 2 58 LYS 58 57 57 LYS LYS B . n B 2 59 GLN 59 58 58 GLN GLN B . n B 2 60 GLN 60 59 59 GLN GLN B . n B 2 61 TRP 61 60 60 TRP TRP B . n B 2 62 VAL 62 61 61 VAL VAL B . n B 2 63 ASP 63 62 62 ASP ASP B . n B 2 64 TYR 64 63 63 TYR TYR B . n B 2 65 ASN 65 64 64 ASN ASN B . n B 2 66 LEU 66 65 65 LEU LEU B . n B 2 67 LYS 67 66 66 LYS LYS B . n B 2 68 TRP 68 67 67 TRP TRP B . n B 2 69 ASN 69 68 68 ASN ASN B . n B 2 70 PRO 70 69 69 PRO PRO B . n B 2 71 ASP 71 70 70 ASP ASP B . n B 2 72 ASP 72 71 71 ASP ASP B . n B 2 73 TYR 73 72 72 TYR TYR B . n B 2 74 GLY 74 73 73 GLY GLY B . n B 2 75 GLY 75 74 74 GLY GLY B . n B 2 76 VAL 76 75 75 VAL VAL B . n B 2 77 LYS 77 76 76 LYS LYS B . n B 2 78 LYS 78 77 77 LYS LYS B . n B 2 79 ILE 79 78 78 ILE ILE B . n B 2 80 HIS 80 79 79 HIS HIS B . n B 2 81 ILE 81 80 80 ILE ILE B . n B 2 82 PRO 82 81 81 PRO PRO B . n B 2 83 SER 83 82 82 SER SER B . n B 2 84 GLU 84 83 83 GLU GLU B . n B 2 85 LYS 85 84 84 LYS LYS B . n B 2 86 ILE 86 85 85 ILE ILE B . n B 2 87 TRP 87 86 86 TRP TRP B . n B 2 88 ARG 88 87 87 ARG ARG B . n B 2 89 PRO 89 88 88 PRO PRO B . n B 2 90 ASP 90 89 89 ASP ASP B . n B 2 91 VAL 91 90 90 VAL VAL B . n B 2 92 VAL 92 91 91 VAL VAL B . n B 2 93 LEU 93 92 92 LEU LEU B . n B 2 94 TYR 94 93 93 TYR TYR B . n B 2 95 ASN 95 94 94 ASN ASN B . n B 2 96 ASN 96 95 95 ASN ASN B . n B 2 97 ALA 97 96 96 ALA ALA B . n B 2 98 ASP 98 97 97 ASP ASP B . n B 2 99 GLY 99 98 98 GLY GLY B . n B 2 100 ASP 100 99 99 ASP ASP B . n B 2 101 PHE 101 100 100 PHE PHE B . n B 2 102 ALA 102 101 101 ALA ALA B . n B 2 103 ILE 103 102 102 ILE ILE B . n B 2 104 VAL 104 103 103 VAL VAL B . n B 2 105 LYS 105 104 104 LYS LYS B . n B 2 106 PHE 106 105 105 PHE PHE B . n B 2 107 THR 107 106 106 THR THR B . n B 2 108 LYS 108 107 107 LYS LYS B . n B 2 109 VAL 109 108 108 VAL VAL B . n B 2 110 LEU 110 109 109 LEU LEU B . n B 2 111 LEU 111 110 110 LEU LEU B . n B 2 112 ASP 112 111 111 ASP ASP B . n B 2 113 TYR 113 112 112 TYR TYR B . n B 2 114 THR 114 113 113 THR THR B . n B 2 115 GLY 115 114 114 GLY GLY B . n B 2 116 HIS 116 115 115 HIS HIS B . n B 2 117 ILE 117 116 116 ILE ILE B . n B 2 118 THR 118 117 117 THR THR B . n B 2 119 TRP 119 118 118 TRP TRP B . n B 2 120 THR 120 119 119 THR THR B . n B 2 121 PRO 121 120 120 PRO PRO B . n B 2 122 PRO 122 121 121 PRO PRO B . n B 2 123 ALA 123 122 122 ALA ALA B . n B 2 124 ILE 124 123 123 ILE ILE B . n B 2 125 PHE 125 124 124 PHE PHE B . n B 2 126 LYS 126 125 125 LYS LYS B . n B 2 127 SER 127 126 126 SER SER B . n B 2 128 TYR 128 127 127 TYR TYR B . n B 2 129 CYS 129 128 128 CYS CYS B . n B 2 130 GLU 130 129 129 GLU GLU B . n B 2 131 ILE 131 130 130 ILE ILE B . n B 2 132 ILE 132 131 131 ILE ILE B . n B 2 133 VAL 133 132 132 VAL VAL B . n B 2 134 THR 134 133 133 THR THR B . n B 2 135 HIS 135 134 134 HIS HIS B . n B 2 136 PHE 136 135 135 PHE PHE B . n B 2 137 PRO 137 136 136 PRO PRO B . n B 2 138 PHE 138 137 137 PHE PHE B . n B 2 139 ASP 139 138 138 ASP ASP B . n B 2 140 GLU 140 139 139 GLU GLU B . n B 2 141 GLN 141 140 140 GLN GLN B . n B 2 142 ASN 142 141 141 ASN ASN B . n B 2 143 CYS 143 142 142 CYS CYS B . n B 2 144 SER 144 143 143 SER SER B . n B 2 145 MET 145 144 144 MET MET B . n B 2 146 LYS 146 145 145 LYS LYS B . n B 2 147 LEU 147 146 146 LEU LEU B . n B 2 148 GLY 148 147 147 GLY GLY B . n B 2 149 THR 149 148 148 THR THR B . n B 2 150 ARG 150 149 149 ARG ARG B . n B 2 151 THR 151 150 150 THR THR B . n B 2 152 TYR 152 151 151 TYR TYR B . n B 2 153 ASP 153 152 152 ASP ASP B . n B 2 154 GLY 154 153 153 GLY GLY B . n B 2 155 SER 155 154 154 SER SER B . n B 2 156 ALA 156 155 155 ALA ALA B . n B 2 157 VAL 157 156 156 VAL VAL B . n B 2 158 ALA 158 157 157 ALA ALA B . n B 2 159 ILE 159 158 158 ILE ILE B . n B 2 160 ASN 160 159 159 ASN ASN B . n B 2 161 PRO 161 160 160 PRO PRO B . n B 2 162 GLU 162 161 161 GLU GLU B . n B 2 163 SER 163 162 162 SER SER B . n B 2 164 ASP 164 163 163 ASP ASP B . n B 2 165 GLN 165 164 164 GLN GLN B . n B 2 166 PRO 166 165 165 PRO PRO B . n B 2 167 ASP 167 166 166 ASP ASP B . n B 2 168 LEU 168 167 167 LEU LEU B . n B 2 169 SER 169 168 168 SER SER B . n B 2 170 ASN 170 169 169 ASN ASN B . n B 2 171 PHE 171 170 170 PHE PHE B . n B 2 172 MET 172 171 171 MET MET B . n B 2 173 GLU 173 172 172 GLU GLU B . n B 2 174 SER 174 173 173 SER SER B . n B 2 175 GLY 175 174 174 GLY GLY B . n B 2 176 GLU 176 175 175 GLU GLU B . n B 2 177 TRP 177 176 176 TRP TRP B . n B 2 178 VAL 178 177 177 VAL VAL B . n B 2 179 ILE 179 178 178 ILE ILE B . n B 2 180 LYS 180 179 179 LYS LYS B . n B 2 181 GLU 181 180 180 GLU GLU B . n B 2 182 ALA 182 181 181 ALA ALA B . n B 2 183 ARG 183 182 182 ARG ARG B . n B 2 184 GLY 184 183 183 GLY GLY B . n B 2 185 TRP 185 184 184 TRP TRP B . n B 2 186 LYS 186 185 185 LYS LYS B . n B 2 187 HIS 187 186 186 HIS HIS B . n B 2 188 TRP 188 187 187 TRP TRP B . n B 2 189 VAL 189 188 188 VAL VAL B . n B 2 190 PHE 190 189 189 PHE PHE B . n B 2 191 TYR 191 190 190 TYR TYR B . n B 2 192 SER 192 191 191 SER SER B . n B 2 193 CYS 193 192 192 CYS CYS B . n B 2 194 CYS 194 193 193 CYS CYS B . n B 2 195 PRO 195 194 194 PRO PRO B . n B 2 196 THR 196 195 195 THR THR B . n B 2 197 THR 197 196 196 THR THR B . n B 2 198 PRO 198 197 197 PRO PRO B . n B 2 199 TYR 199 198 198 TYR TYR B . n B 2 200 LEU 200 199 199 LEU LEU B . n B 2 201 ASP 201 200 200 ASP ASP B . n B 2 202 ILE 202 201 201 ILE ILE B . n B 2 203 THR 203 202 202 THR THR B . n B 2 204 TYR 204 203 203 TYR TYR B . n B 2 205 HIS 205 204 204 HIS HIS B . n B 2 206 PHE 206 205 205 PHE PHE B . n B 2 207 VAL 207 206 206 VAL VAL B . n B 2 208 MET 208 207 207 MET MET B . n B 2 209 GLN 209 208 208 GLN GLN B . n B 2 210 ARG 210 209 209 ARG ARG B . n B 2 211 LEU 211 210 210 LEU LEU B . n B 2 212 PRO 212 211 211 PRO PRO B . n C 3 1 ASP 1 1 1 ASP ASP C . n C 3 2 ILE 2 2 2 ILE ILE C . n C 3 3 VAL 3 3 3 VAL VAL C . n C 3 4 ILE 4 4 4 ILE ILE C . n C 3 5 THR 5 5 5 THR THR C . n C 3 6 GLN 6 6 6 GLN GLN C . n C 3 7 SER 7 7 7 SER SER C . n C 3 8 PRO 8 8 8 PRO PRO C . n C 3 9 SER 9 9 9 SER SER C . n C 3 10 LEU 10 10 10 LEU LEU C . n C 3 11 LEU 11 11 11 LEU LEU C . n C 3 12 SER 12 12 12 SER SER C . n C 3 13 ALA 13 13 13 ALA ALA C . n C 3 14 SER 14 14 14 SER SER C . n C 3 15 VAL 15 15 15 VAL VAL C . n C 3 16 GLY 16 16 16 GLY GLY C . n C 3 17 ASP 17 17 17 ASP ASP C . n C 3 18 ARG 18 18 18 ARG ARG C . n C 3 19 VAL 19 19 19 VAL VAL C . n C 3 20 THR 20 20 20 THR THR C . n C 3 21 LEU 21 21 21 LEU LEU C . n C 3 22 THR 22 22 22 THR THR C . n C 3 23 CYS 23 23 23 CYS CYS C . n C 3 24 LYS 24 24 24 LYS LYS C . n C 3 25 GLY 25 25 25 GLY GLY C . n C 3 26 SER 26 26 26 SER SER C . n C 3 27 GLN 27 27 27 GLN GLN C . n C 3 28 ASN 28 28 28 ASN ASN C . n C 3 29 ILE 29 29 29 ILE ILE C . n C 3 30 ASP 30 30 30 ASP ASP C . n C 3 31 ASN 31 31 31 ASN ASN C . n C 3 32 TYR 32 32 32 TYR TYR C . n C 3 33 LEU 33 33 33 LEU LEU C . n C 3 34 ALA 34 34 34 ALA ALA C . n C 3 35 TRP 35 35 35 TRP TRP C . n C 3 36 TYR 36 36 36 TYR TYR C . n C 3 37 GLN 37 37 37 GLN GLN C . n C 3 38 GLN 38 38 38 GLN GLN C . n C 3 39 LYS 39 39 39 LYS LYS C . n C 3 40 LEU 40 40 40 LEU LEU C . n C 3 41 GLY 41 41 41 GLY GLY C . n C 3 42 GLU 42 42 42 GLU GLU C . n C 3 43 ALA 43 43 43 ALA ALA C . n C 3 44 PRO 44 44 44 PRO PRO C . n C 3 45 LYS 45 45 45 LYS LYS C . n C 3 46 LEU 46 46 46 LEU LEU C . n C 3 47 LEU 47 47 47 LEU LEU C . n C 3 48 ILE 48 48 48 ILE ILE C . n C 3 49 TYR 49 49 49 TYR TYR C . n C 3 50 LYS 50 50 50 LYS LYS C . n C 3 51 THR 51 51 51 THR THR C . n C 3 52 ASN 52 52 52 ASN ASN C . n C 3 53 SER 53 53 53 SER SER C . n C 3 54 LEU 54 54 54 LEU LEU C . n C 3 55 GLN 55 55 55 GLN GLN C . n C 3 56 THR 56 56 56 THR THR C . n C 3 57 GLY 57 57 57 GLY GLY C . n C 3 58 ILE 58 58 58 ILE ILE C . n C 3 59 PRO 59 59 59 PRO PRO C . n C 3 60 SER 60 60 60 SER SER C . n C 3 61 ARG 61 61 61 ARG ARG C . n C 3 62 PHE 62 62 62 PHE PHE C . n C 3 63 SER 63 63 63 SER SER C . n C 3 64 GLY 64 64 64 GLY GLY C . n C 3 65 SER 65 65 65 SER SER C . n C 3 66 GLY 66 66 66 GLY GLY C . n C 3 67 SER 67 67 67 SER SER C . n C 3 68 GLY 68 68 68 GLY GLY C . n C 3 69 THR 69 69 69 THR THR C . n C 3 70 ASP 70 70 70 ASP ASP C . n C 3 71 TYR 71 71 71 TYR TYR C . n C 3 72 THR 72 72 72 THR THR C . n C 3 73 LEU 73 73 73 LEU LEU C . n C 3 74 THR 74 74 74 THR THR C . n C 3 75 ILE 75 75 75 ILE ILE C . n C 3 76 SER 76 76 76 SER SER C . n C 3 77 SER 77 77 77 SER SER C . n C 3 78 LEU 78 78 78 LEU LEU C . n C 3 79 HIS 79 79 79 HIS HIS C . n C 3 80 SER 80 80 80 SER SER C . n C 3 81 GLU 81 81 81 GLU GLU C . n C 3 82 ASP 82 82 82 ASP ASP C . n C 3 83 LEU 83 83 83 LEU LEU C . n C 3 84 ALA 84 84 84 ALA ALA C . n C 3 85 THR 85 85 85 THR THR C . n C 3 86 TYR 86 86 86 TYR TYR C . n C 3 87 TYR 87 87 87 TYR TYR C . n C 3 88 CYS 88 88 88 CYS CYS C . n C 3 89 TYR 89 89 89 TYR TYR C . n C 3 90 GLN 90 90 90 GLN GLN C . n C 3 91 TYR 91 91 91 TYR TYR C . n C 3 92 ILE 92 92 92 ILE ILE C . n C 3 93 ASN 93 93 93 ASN ASN C . n C 3 94 GLY 94 94 94 GLY GLY C . n C 3 95 TYR 95 95 95 TYR TYR C . n C 3 96 THR 96 96 96 THR THR C . n C 3 97 PHE 97 97 97 PHE PHE C . n C 3 98 GLY 98 98 98 GLY GLY C . n C 3 99 THR 99 99 99 THR THR C . n C 3 100 GLY 100 100 100 GLY GLY C . n C 3 101 THR 101 101 101 THR THR C . n C 3 102 LYS 102 102 102 LYS LYS C . n C 3 103 LEU 103 103 103 LEU LEU C . n C 3 104 GLU 104 104 104 GLU GLU C . n C 3 105 LEU 105 105 105 LEU LEU C . n C 3 106 LYS 106 106 106 LYS LYS C . n C 3 107 ARG 107 107 107 ARG ARG C . n C 3 108 ALA 108 108 108 ALA ALA C . n C 3 109 ASP 109 109 109 ASP ASP C . n C 3 110 ALA 110 110 110 ALA ALA C . n C 3 111 ALA 111 111 111 ALA ALA C . n C 3 112 PRO 112 112 112 PRO PRO C . n C 3 113 THR 113 113 113 THR THR C . n C 3 114 VAL 114 114 114 VAL VAL C . n C 3 115 SER 115 115 115 SER SER C . n C 3 116 ILE 116 116 116 ILE ILE C . n C 3 117 PHE 117 117 117 PHE PHE C . n C 3 118 PRO 118 118 118 PRO PRO C . n C 3 119 PRO 119 119 119 PRO PRO C . n C 3 120 SER 120 120 120 SER SER C . n C 3 121 THR 121 121 121 THR THR C . n C 3 122 GLU 122 122 122 GLU GLU C . n C 3 123 GLN 123 123 123 GLN GLN C . n C 3 124 LEU 124 124 124 LEU LEU C . n C 3 125 ALA 125 125 125 ALA ALA C . n C 3 126 THR 126 126 126 THR THR C . n C 3 127 GLY 127 127 127 GLY GLY C . n C 3 128 GLY 128 128 128 GLY GLY C . n C 3 129 ALA 129 129 129 ALA ALA C . n C 3 130 SER 130 130 130 SER SER C . n C 3 131 VAL 131 131 131 VAL VAL C . n C 3 132 VAL 132 132 132 VAL VAL C . n C 3 133 CYS 133 133 133 CYS CYS C . n C 3 134 LEU 134 134 134 LEU LEU C . n C 3 135 MET 135 135 135 MET MET C . n C 3 136 ASN 136 136 136 ASN ASN C . n C 3 137 ASN 137 137 137 ASN ASN C . n C 3 138 PHE 138 138 138 PHE PHE C . n C 3 139 TYR 139 139 139 TYR TYR C . n C 3 140 PRO 140 140 140 PRO PRO C . n C 3 141 ARG 141 141 141 ARG ARG C . n C 3 142 ASP 142 142 142 ASP ASP C . n C 3 143 ILE 143 143 143 ILE ILE C . n C 3 144 SER 144 144 144 SER SER C . n C 3 145 VAL 145 145 145 VAL VAL C . n C 3 146 LYS 146 146 146 LYS LYS C . n C 3 147 TRP 147 147 147 TRP TRP C . n C 3 148 LYS 148 148 148 LYS LYS C . n C 3 149 ILE 149 149 149 ILE ILE C . n C 3 150 ASP 150 150 150 ASP ASP C . n C 3 151 GLY 151 151 151 GLY GLY C . n C 3 152 THR 152 152 152 THR THR C . n C 3 153 GLU 153 153 153 GLU GLU C . n C 3 154 ARG 154 154 154 ARG ARG C . n C 3 155 ARG 155 155 155 ARG ARG C . n C 3 156 ASP 156 156 156 ASP ASP C . n C 3 157 GLY 157 157 157 GLY GLY C . n C 3 158 VAL 158 158 158 VAL VAL C . n C 3 159 LEU 159 159 159 LEU LEU C . n C 3 160 ASP 160 160 160 ASP ASP C . n C 3 161 SER 161 161 161 SER SER C . n C 3 162 VAL 162 162 162 VAL VAL C . n C 3 163 THR 163 163 163 THR THR C . n C 3 164 ASP 164 164 164 ASP ASP C . n C 3 165 GLN 165 165 165 GLN GLN C . n C 3 166 ASP 166 166 166 ASP ASP C . n C 3 167 SER 167 167 167 SER SER C . n C 3 168 LYS 168 168 168 LYS LYS C . n C 3 169 ASP 169 169 169 ASP ASP C . n C 3 170 SER 170 170 170 SER SER C . n C 3 171 THR 171 171 171 THR THR C . n C 3 172 TYR 172 172 172 TYR TYR C . n C 3 173 SER 173 173 173 SER SER C . n C 3 174 MET 174 174 174 MET MET C . n C 3 175 SER 175 175 175 SER SER C . n C 3 176 SER 176 176 176 SER SER C . n C 3 177 THR 177 177 177 THR THR C . n C 3 178 LEU 178 178 178 LEU LEU C . n C 3 179 SER 179 179 179 SER SER C . n C 3 180 LEU 180 180 180 LEU LEU C . n C 3 181 THR 181 181 181 THR THR C . n C 3 182 LYS 182 182 182 LYS LYS C . n C 3 183 ALA 183 183 183 ALA ALA C . n C 3 184 ASP 184 184 184 ASP ASP C . n C 3 185 TYR 185 185 185 TYR TYR C . n C 3 186 GLU 186 186 186 GLU GLU C . n C 3 187 SER 187 187 187 SER SER C . n C 3 188 HIS 188 188 188 HIS HIS C . n C 3 189 ASN 189 189 189 ASN ASN C . n C 3 190 LEU 190 190 190 LEU LEU C . n C 3 191 TYR 191 191 191 TYR TYR C . n C 3 192 THR 192 192 192 THR THR C . n C 3 193 CYS 193 193 193 CYS CYS C . n C 3 194 GLU 194 194 194 GLU GLU C . n C 3 195 VAL 195 195 195 VAL VAL C . n C 3 196 VAL 196 196 196 VAL VAL C . n C 3 197 HIS 197 197 197 HIS HIS C . n C 3 198 LYS 198 198 198 LYS LYS C . n C 3 199 THR 199 199 199 THR THR C . n C 3 200 SER 200 200 200 SER SER C . n C 3 201 SER 201 201 201 SER SER C . n C 3 202 SER 202 202 202 SER SER C . n C 3 203 PRO 203 203 203 PRO PRO C . n C 3 204 VAL 204 204 204 VAL VAL C . n C 3 205 VAL 205 205 205 VAL VAL C . n C 3 206 LYS 206 206 206 LYS LYS C . n C 3 207 SER 207 207 207 SER SER C . n C 3 208 PHE 208 208 208 PHE PHE C . n C 3 209 ASN 209 209 209 ASN ASN C . n C 3 210 ARG 210 210 210 ARG ARG C . n C 3 211 ASN 211 211 211 ASN ASN C . n C 3 212 GLU 212 212 ? ? ? C . n C 3 213 CYS 213 213 ? ? ? C . n D 4 1 GLU 1 1 1 GLU GLU D . n D 4 2 VAL 2 2 2 VAL VAL D . n D 4 3 GLN 3 3 3 GLN GLN D . n D 4 4 LEU 4 4 4 LEU LEU D . n D 4 5 GLN 5 5 5 GLN GLN D . n D 4 6 GLU 6 6 6 GLU GLU D . n D 4 7 SER 7 7 7 SER SER D . n D 4 8 GLY 8 8 8 GLY GLY D . n D 4 9 PRO 9 9 9 PRO PRO D . n D 4 10 GLY 10 10 10 GLY GLY D . n D 4 11 LEU 11 11 11 LEU LEU D . n D 4 12 VAL 12 12 12 VAL VAL D . n D 4 13 GLN 13 13 13 GLN GLN D . n D 4 14 PRO 14 14 14 PRO PRO D . n D 4 15 SER 15 15 15 SER SER D . n D 4 16 GLU 16 16 16 GLU GLU D . n D 4 17 THR 17 17 17 THR THR D . n D 4 18 LEU 18 18 18 LEU LEU D . n D 4 19 SER 19 19 19 SER SER D . n D 4 20 LEU 20 20 20 LEU LEU D . n D 4 21 THR 21 21 21 THR THR D . n D 4 22 CYS 22 22 22 CYS CYS D . n D 4 23 THR 23 23 23 THR THR D . n D 4 24 VAL 24 24 24 VAL VAL D . n D 4 25 SER 25 25 25 SER SER D . n D 4 26 GLY 26 26 26 GLY GLY D . n D 4 27 PHE 27 27 27 PHE PHE D . n D 4 28 SER 28 28 28 SER SER D . n D 4 29 LEU 29 29 29 LEU LEU D . n D 4 30 THR 30 30 30 THR THR D . n D 4 31 SER 31 31 31 SER SER D . n D 4 32 TYR 32 32 32 TYR TYR D . n D 4 33 SER 33 33 33 SER SER D . n D 4 34 VAL 34 34 34 VAL VAL D . n D 4 35 SER 35 35 35 SER SER D . n D 4 36 TRP 36 36 36 TRP TRP D . n D 4 37 LEU 37 37 37 LEU LEU D . n D 4 38 ARG 38 38 38 ARG ARG D . n D 4 39 GLN 39 39 39 GLN GLN D . n D 4 40 PRO 40 40 40 PRO PRO D . n D 4 41 SER 41 41 41 SER SER D . n D 4 42 GLY 42 42 42 GLY GLY D . n D 4 43 LYS 43 43 43 LYS LYS D . n D 4 44 GLY 44 44 44 GLY GLY D . n D 4 45 PRO 45 45 45 PRO PRO D . n D 4 46 GLU 46 46 46 GLU GLU D . n D 4 47 TRP 47 47 47 TRP TRP D . n D 4 48 MET 48 48 48 MET MET D . n D 4 49 GLY 49 49 49 GLY GLY D . n D 4 50 ARG 50 50 50 ARG ARG D . n D 4 51 MET 51 51 51 MET MET D . n D 4 52 TRP 52 52 52 TRP TRP D . n D 4 53 ASP 53 53 53 ASP ASP D . n D 4 54 ASP 54 54 54 ASP ASP D . n D 4 55 GLY 55 55 55 GLY GLY D . n D 4 56 GLY 56 56 56 GLY GLY D . n D 4 57 THR 57 57 57 THR THR D . n D 4 58 VAL 58 58 58 VAL VAL D . n D 4 59 TYR 59 59 59 TYR TYR D . n D 4 60 ASN 60 60 60 ASN ASN D . n D 4 61 SER 61 61 61 SER SER D . n D 4 62 GLY 62 62 62 GLY GLY D . n D 4 63 LEU 63 63 63 LEU LEU D . n D 4 64 LYS 64 64 64 LYS LYS D . n D 4 65 SER 65 65 65 SER SER D . n D 4 66 ARG 66 66 66 ARG ARG D . n D 4 67 LEU 67 67 67 LEU LEU D . n D 4 68 SER 68 68 68 SER SER D . n D 4 69 ILE 69 69 69 ILE ILE D . n D 4 70 SER 70 70 70 SER SER D . n D 4 71 ARG 71 71 71 ARG ARG D . n D 4 72 ASP 72 72 72 ASP ASP D . n D 4 73 THR 73 73 73 THR THR D . n D 4 74 SER 74 74 74 SER SER D . n D 4 75 LYS 75 75 75 LYS LYS D . n D 4 76 ASN 76 76 76 ASN ASN D . n D 4 77 GLN 77 77 77 GLN GLN D . n D 4 78 VAL 78 78 78 VAL VAL D . n D 4 79 PHE 79 79 79 PHE PHE D . n D 4 80 LEU 80 80 80 LEU LEU D . n D 4 81 LYS 81 81 81 LYS LYS D . n D 4 82 MET 82 82 82 MET MET D . n D 4 83 ASN 83 83 83 ASN ASN D . n D 4 84 SER 84 84 84 SER SER D . n D 4 85 LEU 85 85 85 LEU LEU D . n D 4 86 GLN 86 86 86 GLN GLN D . n D 4 87 THR 87 87 87 THR THR D . n D 4 88 ASP 88 88 88 ASP ASP D . n D 4 89 ASP 89 89 89 ASP ASP D . n D 4 90 THR 90 90 90 THR THR D . n D 4 91 GLY 91 91 91 GLY GLY D . n D 4 92 THR 92 92 92 THR THR D . n D 4 93 TYR 93 93 93 TYR TYR D . n D 4 94 TYR 94 94 94 TYR TYR D . n D 4 95 CYS 95 95 95 CYS CYS D . n D 4 96 THR 96 96 96 THR THR D . n D 4 97 ARG 97 97 97 ARG ARG D . n D 4 98 ASP 98 98 98 ASP ASP D . n D 4 99 GLU 99 99 99 GLU GLU D . n D 4 100 ARG 100 100 100 ARG ARG D . n D 4 101 ILE 101 101 101 ILE ILE D . n D 4 102 ARG 102 102 102 ARG ARG D . n D 4 103 ALA 103 103 103 ALA ALA D . n D 4 104 ILE 104 104 104 ILE ILE D . n D 4 105 ASN 105 105 105 ASN ASN D . n D 4 106 TRP 106 106 106 TRP TRP D . n D 4 107 PHE 107 107 107 PHE PHE D . n D 4 108 ALA 108 108 108 ALA ALA D . n D 4 109 TYR 109 109 109 TYR TYR D . n D 4 110 TRP 110 110 110 TRP TRP D . n D 4 111 GLY 111 111 111 GLY GLY D . n D 4 112 GLN 112 112 112 GLN GLN D . n D 4 113 GLY 113 113 113 GLY GLY D . n D 4 114 THR 114 114 114 THR THR D . n D 4 115 LEU 115 115 115 LEU LEU D . n D 4 116 VAL 116 116 116 VAL VAL D . n D 4 117 THR 117 117 117 THR THR D . n D 4 118 VAL 118 118 118 VAL VAL D . n D 4 119 SER 119 119 119 SER SER D . n D 4 120 SER 120 120 120 SER SER D . n D 4 121 ALA 121 121 121 ALA ALA D . n D 4 122 GLU 122 122 122 GLU GLU D . n D 4 123 THR 123 123 123 THR THR D . n D 4 124 THR 124 124 124 THR THR D . n D 4 125 ALA 125 125 125 ALA ALA D . n D 4 126 PRO 126 126 126 PRO PRO D . n D 4 127 SER 127 127 127 SER SER D . n D 4 128 VAL 128 128 128 VAL VAL D . n D 4 129 TYR 129 129 129 TYR TYR D . n D 4 130 PRO 130 130 130 PRO PRO D . n D 4 131 LEU 131 131 131 LEU LEU D . n D 4 132 ALA 132 132 132 ALA ALA D . n D 4 133 PRO 133 133 133 PRO PRO D . n D 4 134 GLY 134 134 134 GLY GLY D . n D 4 135 THR 135 135 135 THR THR D . n D 4 136 ALA 136 136 136 ALA ALA D . n D 4 137 LEU 137 137 137 LEU LEU D . n D 4 138 LYS 138 138 138 LYS LYS D . n D 4 139 SER 139 139 139 SER SER D . n D 4 140 ASN 140 140 140 ASN ASN D . n D 4 141 SER 141 141 141 SER SER D . n D 4 142 MET 142 142 142 MET MET D . n D 4 143 VAL 143 143 143 VAL VAL D . n D 4 144 THR 144 144 144 THR THR D . n D 4 145 LEU 145 145 145 LEU LEU D . n D 4 146 GLY 146 146 146 GLY GLY D . n D 4 147 CYS 147 147 147 CYS CYS D . n D 4 148 LEU 148 148 148 LEU LEU D . n D 4 149 VAL 149 149 149 VAL VAL D . n D 4 150 LYS 150 150 150 LYS LYS D . n D 4 151 GLY 151 151 151 GLY GLY D . n D 4 152 TYR 152 152 152 TYR TYR D . n D 4 153 PHE 153 153 153 PHE PHE D . n D 4 154 PRO 154 154 154 PRO PRO D . n D 4 155 GLU 155 155 155 GLU GLU D . n D 4 156 PRO 156 156 156 PRO PRO D . n D 4 157 VAL 157 157 157 VAL VAL D . n D 4 158 THR 158 158 158 THR THR D . n D 4 159 VAL 159 159 159 VAL VAL D . n D 4 160 THR 160 160 160 THR THR D . n D 4 161 TRP 161 161 161 TRP TRP D . n D 4 162 ASN 162 162 162 ASN ASN D . n D 4 163 SER 163 163 163 SER SER D . n D 4 164 GLY 164 164 164 GLY GLY D . n D 4 165 ALA 165 165 165 ALA ALA D . n D 4 166 LEU 166 166 166 LEU LEU D . n D 4 167 SER 167 167 167 SER SER D . n D 4 168 SER 168 168 168 SER SER D . n D 4 169 GLY 169 169 169 GLY GLY D . n D 4 170 VAL 170 170 170 VAL VAL D . n D 4 171 HIS 171 171 171 HIS HIS D . n D 4 172 THR 172 172 172 THR THR D . n D 4 173 PHE 173 173 173 PHE PHE D . n D 4 174 PRO 174 174 174 PRO PRO D . n D 4 175 ALA 175 175 175 ALA ALA D . n D 4 176 VAL 176 176 176 VAL VAL D . n D 4 177 LEU 177 177 177 LEU LEU D . n D 4 178 GLN 178 178 178 GLN GLN D . n D 4 179 SER 179 179 179 SER SER D . n D 4 180 GLY 180 180 180 GLY GLY D . n D 4 181 LEU 181 181 181 LEU LEU D . n D 4 182 TYR 182 182 182 TYR TYR D . n D 4 183 THR 183 183 183 THR THR D . n D 4 184 LEU 184 184 184 LEU LEU D . n D 4 185 THR 185 185 185 THR THR D . n D 4 186 SER 186 186 186 SER SER D . n D 4 187 SER 187 187 187 SER SER D . n D 4 188 VAL 188 188 188 VAL VAL D . n D 4 189 THR 189 189 189 THR THR D . n D 4 190 VAL 190 190 190 VAL VAL D . n D 4 191 PRO 191 191 191 PRO PRO D . n D 4 192 SER 192 192 192 SER SER D . n D 4 193 SER 193 193 193 SER SER D . n D 4 194 THR 194 194 194 THR THR D . n D 4 195 TRP 195 195 195 TRP TRP D . n D 4 196 PRO 196 196 196 PRO PRO D . n D 4 197 SER 197 197 197 SER SER D . n D 4 198 GLN 198 198 198 GLN GLN D . n D 4 199 THR 199 199 199 THR THR D . n D 4 200 VAL 200 200 200 VAL VAL D . n D 4 201 THR 201 201 201 THR THR D . n D 4 202 CYS 202 202 202 CYS CYS D . n D 4 203 ASN 203 203 203 ASN ASN D . n D 4 204 VAL 204 204 204 VAL VAL D . n D 4 205 ALA 205 205 205 ALA ALA D . n D 4 206 HIS 206 206 206 HIS HIS D . n D 4 207 PRO 207 207 207 PRO PRO D . n D 4 208 GLY 208 208 208 GLY GLY D . n D 4 209 GLN 209 209 209 GLN GLN D . n D 4 210 GLN 210 210 210 GLN GLN D . n D 4 211 HIS 211 211 211 HIS HIS D . n D 4 212 GLN 212 212 212 GLN GLN D . n D 4 213 ARG 213 213 213 ARG ARG D . n D 4 214 TRP 214 214 214 TRP TRP D . n D 4 215 THR 215 215 215 THR THR D . n D 4 216 ARG 216 216 216 ARG ARG D . n D 4 217 LYS 217 217 217 LYS LYS D . n D 4 218 LEU 218 218 218 LEU LEU D . n D 4 219 CYS 219 219 219 CYS CYS D . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code E 5 NAG 1 301 302 NAG NAG B . F 5 NAG 2 302 303 NAG NAG B . G 6 BMA 3 303 304 BMA BMA B . H 7 MAN 4 304 305 MAN MAN B . I 7 MAN 5 305 306 MAN MAN B . J 7 MAN 6 306 307 MAN MAN B . K 7 MAN 7 307 308 MAN MAN B . L 7 MAN 8 308 309 MAN MAN B . M 7 MAN 9 309 311 MAN MAN B . N 8 HOH 1 101 14 HOH HOH A . N 8 HOH 2 102 7 HOH HOH A . N 8 HOH 3 103 17 HOH HOH A . O 8 HOH 1 401 10 HOH HOH B . O 8 HOH 2 402 56 HOH HOH B . O 8 HOH 3 403 54 HOH HOH B . O 8 HOH 4 404 18 HOH HOH B . O 8 HOH 5 405 1 HOH HOH B . O 8 HOH 6 406 2 HOH HOH B . O 8 HOH 7 407 12 HOH HOH B . O 8 HOH 8 408 3 HOH HOH B . O 8 HOH 9 409 55 HOH HOH B . O 8 HOH 10 410 28 HOH HOH B . O 8 HOH 11 411 15 HOH HOH B . O 8 HOH 12 412 57 HOH HOH B . O 8 HOH 13 413 51 HOH HOH B . O 8 HOH 14 414 6 HOH HOH B . O 8 HOH 15 415 83 HOH HOH B . O 8 HOH 16 416 26 HOH HOH B . O 8 HOH 17 417 89 HOH HOH B . O 8 HOH 18 418 20 HOH HOH B . O 8 HOH 19 419 101 HOH HOH B . O 8 HOH 20 420 104 HOH HOH B . O 8 HOH 21 421 16 HOH HOH B . O 8 HOH 22 422 43 HOH HOH B . O 8 HOH 23 423 19 HOH HOH B . O 8 HOH 24 424 46 HOH HOH B . O 8 HOH 25 425 8 HOH HOH B . O 8 HOH 26 426 21 HOH HOH B . O 8 HOH 27 427 60 HOH HOH B . P 8 HOH 1 301 105 HOH HOH C . P 8 HOH 2 302 73 HOH HOH C . P 8 HOH 3 303 205 HOH HOH C . P 8 HOH 4 304 9 HOH HOH C . P 8 HOH 5 305 58 HOH HOH C . P 8 HOH 6 306 132 HOH HOH C . P 8 HOH 7 307 11 HOH HOH C . P 8 HOH 8 308 35 HOH HOH C . Q 8 HOH 1 301 4 HOH HOH D . Q 8 HOH 2 302 5 HOH HOH D . Q 8 HOH 3 303 33 HOH HOH D . Q 8 HOH 4 304 118 HOH HOH D . Q 8 HOH 5 305 22 HOH HOH D . Q 8 HOH 6 306 59 HOH HOH D . Q 8 HOH 7 307 13 HOH HOH D . Q 8 HOH 8 308 202 HOH HOH D . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details tetrameric _pdbx_struct_assembly.oligomeric_count 4 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2017-05-03 2 'Structure model' 1 1 2017-05-10 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Database references' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0158 1 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 2 ? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? 3.15 3 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 4 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? . 5 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 30 ? ? -112.32 -166.87 2 1 GLU A 56 ? ? -150.67 79.08 3 1 ASN A 66 ? ? -118.89 55.14 4 1 LEU B 56 ? ? -107.38 79.86 5 1 ALA B 181 ? ? -166.76 119.78 6 1 LEU C 47 ? ? -96.73 -61.69 7 1 LYS C 50 ? ? 39.20 57.74 8 1 THR C 51 ? ? 67.75 -53.08 9 1 TYR C 91 ? ? -145.44 31.10 10 1 ASN C 137 ? ? 63.44 78.63 11 1 SER D 68 ? ? -165.05 113.41 12 1 ARG D 102 ? ? 52.48 -117.02 13 1 LEU D 137 ? ? -76.19 -73.60 14 1 ASN D 162 ? ? 31.19 73.89 15 1 SER D 163 ? ? 61.93 -97.75 16 1 SER D 167 ? ? 58.12 -106.91 17 1 SER D 179 ? ? -153.53 71.93 18 1 LEU D 218 ? ? -102.65 58.19 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A ARG 72 ? CG ? A ARG 72 CG 2 1 Y 1 A ARG 72 ? CD ? A ARG 72 CD 3 1 Y 1 A ARG 72 ? NE ? A ARG 72 NE 4 1 Y 1 A ARG 72 ? CZ ? A ARG 72 CZ 5 1 Y 1 A ARG 72 ? NH1 ? A ARG 72 NH1 6 1 Y 1 A ARG 72 ? NH2 ? A ARG 72 NH2 7 1 Y 1 B LYS 77 ? CE ? B LYS 78 CE 8 1 Y 1 B LYS 77 ? NZ ? B LYS 78 NZ 9 1 Y 1 B PHE 137 ? CG ? B PHE 138 CG 10 1 Y 1 B PHE 137 ? CD1 ? B PHE 138 CD1 11 1 Y 1 B PHE 137 ? CD2 ? B PHE 138 CD2 12 1 Y 1 B PHE 137 ? CE1 ? B PHE 138 CE1 13 1 Y 1 B PHE 137 ? CE2 ? B PHE 138 CE2 14 1 Y 1 B PHE 137 ? CZ ? B PHE 138 CZ 15 1 Y 1 C ARG 210 ? CZ ? C ARG 210 CZ 16 1 Y 1 C ARG 210 ? NH1 ? C ARG 210 NH1 17 1 Y 1 C ARG 210 ? NH2 ? C ARG 210 NH2 18 1 Y 1 D LEU 166 ? CG ? D LEU 166 CG 19 1 Y 1 D LEU 166 ? CD1 ? D LEU 166 CD1 20 1 Y 1 D LEU 166 ? CD2 ? D LEU 166 CD2 21 1 Y 1 D TRP 195 ? CG ? D TRP 195 CG 22 1 Y 1 D TRP 195 ? CD1 ? D TRP 195 CD1 23 1 Y 1 D TRP 195 ? CD2 ? D TRP 195 CD2 24 1 Y 1 D TRP 195 ? NE1 ? D TRP 195 NE1 25 1 Y 1 D TRP 195 ? CE2 ? D TRP 195 CE2 26 1 Y 1 D TRP 195 ? CE3 ? D TRP 195 CE3 27 1 Y 1 D TRP 195 ? CZ2 ? D TRP 195 CZ2 28 1 Y 1 D TRP 195 ? CZ3 ? D TRP 195 CZ3 29 1 Y 1 D TRP 195 ? CH2 ? D TRP 195 CH2 30 1 Y 1 D GLN 209 ? CG ? D GLN 209 CG 31 1 Y 1 D GLN 209 ? CD ? D GLN 209 CD 32 1 Y 1 D GLN 209 ? OE1 ? D GLN 209 OE1 33 1 Y 1 D GLN 209 ? NE2 ? D GLN 209 NE2 34 1 Y 1 D GLN 210 ? CG ? D GLN 210 CG 35 1 Y 1 D GLN 210 ? CD ? D GLN 210 CD 36 1 Y 1 D GLN 210 ? OE1 ? D GLN 210 OE1 37 1 Y 1 D GLN 210 ? NE2 ? D GLN 210 NE2 38 1 Y 1 D HIS 211 ? CG ? D HIS 211 CG 39 1 Y 1 D HIS 211 ? ND1 ? D HIS 211 ND1 40 1 Y 1 D HIS 211 ? CD2 ? D HIS 211 CD2 41 1 Y 1 D HIS 211 ? CE1 ? D HIS 211 CE1 42 1 Y 1 D HIS 211 ? NE2 ? D HIS 211 NE2 43 1 Y 1 D ARG 216 ? CG ? D ARG 216 CG 44 1 Y 1 D ARG 216 ? CD ? D ARG 216 CD 45 1 Y 1 D ARG 216 ? NE ? D ARG 216 NE 46 1 Y 1 D ARG 216 ? CZ ? D ARG 216 CZ 47 1 Y 1 D ARG 216 ? NH1 ? D ARG 216 NH1 48 1 Y 1 D ARG 216 ? NH2 ? D ARG 216 NH2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 C GLU 212 ? C GLU 212 2 1 Y 1 C CYS 213 ? C CYS 213 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 5 N-ACETYL-D-GLUCOSAMINE NAG 6 BETA-D-MANNOSE BMA 7 ALPHA-D-MANNOSE MAN 8 water HOH #