data_5FBK # _entry.id 5FBK # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5FBK WWPDB D_1000216321 # _pdbx_database_related.content_type unspecified _pdbx_database_related.db_id 5FBH _pdbx_database_related.db_name PDB _pdbx_database_related.details . # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5FBK _pdbx_database_status.recvd_initial_deposition_date 2015-12-14 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Zhang, T.' 1 'Zhang, C.' 2 'Miller, C.L.' 3 'Zou, J.' 4 'Moremen, K.W.' 5 'Brown, E.M.' 6 'Yang, J.J.' 7 'Hu, J.' 8 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'Sci Adv' _citation.journal_id_ASTM ? _citation.journal_id_CSD ? _citation.journal_id_ISSN 2375-2548 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 2 _citation.language ? _citation.page_first e1600241 _citation.page_last e1600241 _citation.title ;Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist. ; _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1126/sciadv.1600241 _citation.pdbx_database_id_PubMed 27386547 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Zhang, C.' 1 primary 'Zhang, T.' 2 primary 'Zou, J.' 3 primary 'Miller, C.L.' 4 primary 'Gorkhali, R.' 5 primary 'Yang, J.Y.' 6 primary 'Schilmiller, A.' 7 primary 'Wang, S.' 8 primary 'Huang, K.' 9 primary 'Brown, E.M.' 10 primary 'Moremen, K.W.' 11 primary 'Hu, J.' 12 primary 'Yang, J.J.' 13 # _cell.angle_alpha 90.000 _cell.angle_alpha_esd ? _cell.angle_beta 105.100 _cell.angle_beta_esd ? _cell.angle_gamma 90.000 _cell.angle_gamma_esd ? _cell.entry_id 5FBK _cell.details ? _cell.formula_units_Z ? _cell.length_a 170.872 _cell.length_a_esd ? _cell.length_b 82.916 _cell.length_b_esd ? _cell.length_c 94.256 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 8 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 5FBK _symmetry.cell_setting ? _symmetry.Int_Tables_number 5 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'C 1 2 1' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Extracellular calcium-sensing receptor' 64215.383 2 ? ? 'UNP residues 20-541' ? 2 non-polymer syn CYCLOMETHYLTRYPTOPHAN 216.236 2 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 8 ? ? ? ? 4 non-polymer syn 'CHLORIDE ION' 35.453 6 ? ? ? ? 5 non-polymer syn 'BICARBONATE ION' 61.017 2 ? ? ? ? 6 non-polymer syn 'MAGNESIUM ION' 24.305 3 ? ? ? ? 7 water nat water 18.015 323 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'CaSR,Parathyroid cell calcium-sensing receptor 1,PCaR1' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer yes _entity_poly.pdbx_seq_one_letter_code ;MRLLTALFAYFIVALILAFSVSAKSMHHHHHHHHSAWSHPQFEKEFYGPDQRAQKKGDIILGGLFPIHFGVAAKDQDLKS RPESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSE HIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIA ADDDYGRPGIEKFREEAEERDI(CSO)IDFSELISQYSDEEEIQHVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNIT GKIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHLQEGAKGPLP VDTFLRGHEESGDRFSNSSTAFRPLCTGDENISSVETPYIDYTHLRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSC ADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDE(CSO)GDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINE EKILWSGFSREVPFSN ; _entity_poly.pdbx_seq_one_letter_code_can ;MRLLTALFAYFIVALILAFSVSAKSMHHHHHHHHSAWSHPQFEKEFYGPDQRAQKKGDIILGGLFPIHFGVAAKDQDLKS RPESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSE HIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIA ADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGKIW LASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTF LRGHEESGDRFSNSSTAFRPLCTGDENISSVETPYIDYTHLRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIK KVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGF SREVPFSN ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 MET n 1 2 ARG n 1 3 LEU n 1 4 LEU n 1 5 THR n 1 6 ALA n 1 7 LEU n 1 8 PHE n 1 9 ALA n 1 10 TYR n 1 11 PHE n 1 12 ILE n 1 13 VAL n 1 14 ALA n 1 15 LEU n 1 16 ILE n 1 17 LEU n 1 18 ALA n 1 19 PHE n 1 20 SER n 1 21 VAL n 1 22 SER n 1 23 ALA n 1 24 LYS n 1 25 SER n 1 26 MET n 1 27 HIS n 1 28 HIS n 1 29 HIS n 1 30 HIS n 1 31 HIS n 1 32 HIS n 1 33 HIS n 1 34 HIS n 1 35 SER n 1 36 ALA n 1 37 TRP n 1 38 SER n 1 39 HIS n 1 40 PRO n 1 41 GLN n 1 42 PHE n 1 43 GLU n 1 44 LYS n 1 45 GLU n 1 46 PHE n 1 47 TYR n 1 48 GLY n 1 49 PRO n 1 50 ASP n 1 51 GLN n 1 52 ARG n 1 53 ALA n 1 54 GLN n 1 55 LYS n 1 56 LYS n 1 57 GLY n 1 58 ASP n 1 59 ILE n 1 60 ILE n 1 61 LEU n 1 62 GLY n 1 63 GLY n 1 64 LEU n 1 65 PHE n 1 66 PRO n 1 67 ILE n 1 68 HIS n 1 69 PHE n 1 70 GLY n 1 71 VAL n 1 72 ALA n 1 73 ALA n 1 74 LYS n 1 75 ASP n 1 76 GLN n 1 77 ASP n 1 78 LEU n 1 79 LYS n 1 80 SER n 1 81 ARG n 1 82 PRO n 1 83 GLU n 1 84 SER n 1 85 VAL n 1 86 GLU n 1 87 CYS n 1 88 ILE n 1 89 ARG n 1 90 TYR n 1 91 ASN n 1 92 PHE n 1 93 ARG n 1 94 GLY n 1 95 PHE n 1 96 ARG n 1 97 TRP n 1 98 LEU n 1 99 GLN n 1 100 ALA n 1 101 MET n 1 102 ILE n 1 103 PHE n 1 104 ALA n 1 105 ILE n 1 106 GLU n 1 107 GLU n 1 108 ILE n 1 109 ASN n 1 110 SER n 1 111 SER n 1 112 PRO n 1 113 ALA n 1 114 LEU n 1 115 LEU n 1 116 PRO n 1 117 ASN n 1 118 LEU n 1 119 THR n 1 120 LEU n 1 121 GLY n 1 122 TYR n 1 123 ARG n 1 124 ILE n 1 125 PHE n 1 126 ASP n 1 127 THR n 1 128 CYS n 1 129 ASN n 1 130 THR n 1 131 VAL n 1 132 SER n 1 133 LYS n 1 134 ALA n 1 135 LEU n 1 136 GLU n 1 137 ALA n 1 138 THR n 1 139 LEU n 1 140 SER n 1 141 PHE n 1 142 VAL n 1 143 ALA n 1 144 GLN n 1 145 ASN n 1 146 LYS n 1 147 ILE n 1 148 ASP n 1 149 SER n 1 150 LEU n 1 151 ASN n 1 152 LEU n 1 153 ASP n 1 154 GLU n 1 155 PHE n 1 156 CYS n 1 157 ASN n 1 158 CYS n 1 159 SER n 1 160 GLU n 1 161 HIS n 1 162 ILE n 1 163 PRO n 1 164 SER n 1 165 THR n 1 166 ILE n 1 167 ALA n 1 168 VAL n 1 169 VAL n 1 170 GLY n 1 171 ALA n 1 172 THR n 1 173 GLY n 1 174 SER n 1 175 GLY n 1 176 VAL n 1 177 SER n 1 178 THR n 1 179 ALA n 1 180 VAL n 1 181 ALA n 1 182 ASN n 1 183 LEU n 1 184 LEU n 1 185 GLY n 1 186 LEU n 1 187 PHE n 1 188 TYR n 1 189 ILE n 1 190 PRO n 1 191 GLN n 1 192 VAL n 1 193 SER n 1 194 TYR n 1 195 ALA n 1 196 SER n 1 197 SER n 1 198 SER n 1 199 ARG n 1 200 LEU n 1 201 LEU n 1 202 SER n 1 203 ASN n 1 204 LYS n 1 205 ASN n 1 206 GLN n 1 207 PHE n 1 208 LYS n 1 209 SER n 1 210 PHE n 1 211 LEU n 1 212 ARG n 1 213 THR n 1 214 ILE n 1 215 PRO n 1 216 ASN n 1 217 ASP n 1 218 GLU n 1 219 HIS n 1 220 GLN n 1 221 ALA n 1 222 THR n 1 223 ALA n 1 224 MET n 1 225 ALA n 1 226 ASP n 1 227 ILE n 1 228 ILE n 1 229 GLU n 1 230 TYR n 1 231 PHE n 1 232 ARG n 1 233 TRP n 1 234 ASN n 1 235 TRP n 1 236 VAL n 1 237 GLY n 1 238 THR n 1 239 ILE n 1 240 ALA n 1 241 ALA n 1 242 ASP n 1 243 ASP n 1 244 ASP n 1 245 TYR n 1 246 GLY n 1 247 ARG n 1 248 PRO n 1 249 GLY n 1 250 ILE n 1 251 GLU n 1 252 LYS n 1 253 PHE n 1 254 ARG n 1 255 GLU n 1 256 GLU n 1 257 ALA n 1 258 GLU n 1 259 GLU n 1 260 ARG n 1 261 ASP n 1 262 ILE n 1 263 CSO n 1 264 ILE n 1 265 ASP n 1 266 PHE n 1 267 SER n 1 268 GLU n 1 269 LEU n 1 270 ILE n 1 271 SER n 1 272 GLN n 1 273 TYR n 1 274 SER n 1 275 ASP n 1 276 GLU n 1 277 GLU n 1 278 GLU n 1 279 ILE n 1 280 GLN n 1 281 HIS n 1 282 VAL n 1 283 VAL n 1 284 GLU n 1 285 VAL n 1 286 ILE n 1 287 GLN n 1 288 ASN n 1 289 SER n 1 290 THR n 1 291 ALA n 1 292 LYS n 1 293 VAL n 1 294 ILE n 1 295 VAL n 1 296 VAL n 1 297 PHE n 1 298 SER n 1 299 SER n 1 300 GLY n 1 301 PRO n 1 302 ASP n 1 303 LEU n 1 304 GLU n 1 305 PRO n 1 306 LEU n 1 307 ILE n 1 308 LYS n 1 309 GLU n 1 310 ILE n 1 311 VAL n 1 312 ARG n 1 313 ARG n 1 314 ASN n 1 315 ILE n 1 316 THR n 1 317 GLY n 1 318 LYS n 1 319 ILE n 1 320 TRP n 1 321 LEU n 1 322 ALA n 1 323 SER n 1 324 GLU n 1 325 ALA n 1 326 TRP n 1 327 ALA n 1 328 SER n 1 329 SER n 1 330 SER n 1 331 LEU n 1 332 ILE n 1 333 ALA n 1 334 MET n 1 335 PRO n 1 336 GLN n 1 337 TYR n 1 338 PHE n 1 339 HIS n 1 340 VAL n 1 341 VAL n 1 342 GLY n 1 343 GLY n 1 344 THR n 1 345 ILE n 1 346 GLY n 1 347 PHE n 1 348 ALA n 1 349 LEU n 1 350 LYS n 1 351 ALA n 1 352 GLY n 1 353 GLN n 1 354 ILE n 1 355 PRO n 1 356 GLY n 1 357 PHE n 1 358 ARG n 1 359 GLU n 1 360 PHE n 1 361 LEU n 1 362 LYS n 1 363 LYS n 1 364 VAL n 1 365 HIS n 1 366 PRO n 1 367 ARG n 1 368 LYS n 1 369 SER n 1 370 VAL n 1 371 HIS n 1 372 ASN n 1 373 GLY n 1 374 PHE n 1 375 ALA n 1 376 LYS n 1 377 GLU n 1 378 PHE n 1 379 TRP n 1 380 GLU n 1 381 GLU n 1 382 THR n 1 383 PHE n 1 384 ASN n 1 385 CYS n 1 386 HIS n 1 387 LEU n 1 388 GLN n 1 389 GLU n 1 390 GLY n 1 391 ALA n 1 392 LYS n 1 393 GLY n 1 394 PRO n 1 395 LEU n 1 396 PRO n 1 397 VAL n 1 398 ASP n 1 399 THR n 1 400 PHE n 1 401 LEU n 1 402 ARG n 1 403 GLY n 1 404 HIS n 1 405 GLU n 1 406 GLU n 1 407 SER n 1 408 GLY n 1 409 ASP n 1 410 ARG n 1 411 PHE n 1 412 SER n 1 413 ASN n 1 414 SER n 1 415 SER n 1 416 THR n 1 417 ALA n 1 418 PHE n 1 419 ARG n 1 420 PRO n 1 421 LEU n 1 422 CYS n 1 423 THR n 1 424 GLY n 1 425 ASP n 1 426 GLU n 1 427 ASN n 1 428 ILE n 1 429 SER n 1 430 SER n 1 431 VAL n 1 432 GLU n 1 433 THR n 1 434 PRO n 1 435 TYR n 1 436 ILE n 1 437 ASP n 1 438 TYR n 1 439 THR n 1 440 HIS n 1 441 LEU n 1 442 ARG n 1 443 ILE n 1 444 SER n 1 445 TYR n 1 446 ASN n 1 447 VAL n 1 448 TYR n 1 449 LEU n 1 450 ALA n 1 451 VAL n 1 452 TYR n 1 453 SER n 1 454 ILE n 1 455 ALA n 1 456 HIS n 1 457 ALA n 1 458 LEU n 1 459 GLN n 1 460 ASP n 1 461 ILE n 1 462 TYR n 1 463 THR n 1 464 CYS n 1 465 LEU n 1 466 PRO n 1 467 GLY n 1 468 ARG n 1 469 GLY n 1 470 LEU n 1 471 PHE n 1 472 THR n 1 473 ASN n 1 474 GLY n 1 475 SER n 1 476 CYS n 1 477 ALA n 1 478 ASP n 1 479 ILE n 1 480 LYS n 1 481 LYS n 1 482 VAL n 1 483 GLU n 1 484 ALA n 1 485 TRP n 1 486 GLN n 1 487 VAL n 1 488 LEU n 1 489 LYS n 1 490 HIS n 1 491 LEU n 1 492 ARG n 1 493 HIS n 1 494 LEU n 1 495 ASN n 1 496 PHE n 1 497 THR n 1 498 ASN n 1 499 ASN n 1 500 MET n 1 501 GLY n 1 502 GLU n 1 503 GLN n 1 504 VAL n 1 505 THR n 1 506 PHE n 1 507 ASP n 1 508 GLU n 1 509 CSO n 1 510 GLY n 1 511 ASP n 1 512 LEU n 1 513 VAL n 1 514 GLY n 1 515 ASN n 1 516 TYR n 1 517 SER n 1 518 ILE n 1 519 ILE n 1 520 ASN n 1 521 TRP n 1 522 HIS n 1 523 LEU n 1 524 SER n 1 525 PRO n 1 526 GLU n 1 527 ASP n 1 528 GLY n 1 529 SER n 1 530 ILE n 1 531 VAL n 1 532 PHE n 1 533 LYS n 1 534 GLU n 1 535 VAL n 1 536 GLY n 1 537 TYR n 1 538 TYR n 1 539 ASN n 1 540 VAL n 1 541 TYR n 1 542 ALA n 1 543 LYS n 1 544 LYS n 1 545 GLY n 1 546 GLU n 1 547 ARG n 1 548 LEU n 1 549 PHE n 1 550 ILE n 1 551 ASN n 1 552 GLU n 1 553 GLU n 1 554 LYS n 1 555 ILE n 1 556 LEU n 1 557 TRP n 1 558 SER n 1 559 GLY n 1 560 PHE n 1 561 SER n 1 562 ARG n 1 563 GLU n 1 564 VAL n 1 565 PRO n 1 566 PHE n 1 567 SER n 1 568 ASN n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 568 _entity_src_gen.gene_src_common_name Human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'CASR, GPRC2A, PCAR1' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 9606 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line HEK293 _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code CASR_HUMAN _struct_ref.pdbx_db_accession P41180 _struct_ref.pdbx_db_isoform ? _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;YGPDQRAQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFD TCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQ FKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHVVEVI QNSTAKVIVVFSSGPDLEPLIKEIVRRNITGKIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHP RKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSNSSTAFRPLCTGDENISSVETPYIDYTHLRISYN VYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNYSIINWHLSPE DGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFSREVPFSN ; _struct_ref.pdbx_align_begin 20 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5FBK A 47 ? 568 ? P41180 20 ? 541 ? 20 541 2 1 5FBK B 47 ? 568 ? P41180 20 ? 541 ? 20 541 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 5FBK MET A 1 ? UNP P41180 ? ? 'initiating methionine' -26 1 1 5FBK ARG A 2 ? UNP P41180 ? ? 'expression tag' -25 2 1 5FBK LEU A 3 ? UNP P41180 ? ? 'expression tag' -24 3 1 5FBK LEU A 4 ? UNP P41180 ? ? 'expression tag' -23 4 1 5FBK THR A 5 ? UNP P41180 ? ? 'expression tag' -22 5 1 5FBK ALA A 6 ? UNP P41180 ? ? 'expression tag' -21 6 1 5FBK LEU A 7 ? UNP P41180 ? ? 'expression tag' -20 7 1 5FBK PHE A 8 ? UNP P41180 ? ? 'expression tag' -19 8 1 5FBK ALA A 9 ? UNP P41180 ? ? 'expression tag' -18 9 1 5FBK TYR A 10 ? UNP P41180 ? ? 'expression tag' -17 10 1 5FBK PHE A 11 ? UNP P41180 ? ? 'expression tag' -16 11 1 5FBK ILE A 12 ? UNP P41180 ? ? 'expression tag' -15 12 1 5FBK VAL A 13 ? UNP P41180 ? ? 'expression tag' -14 13 1 5FBK ALA A 14 ? UNP P41180 ? ? 'expression tag' -13 14 1 5FBK LEU A 15 ? UNP P41180 ? ? 'expression tag' -12 15 1 5FBK ILE A 16 ? UNP P41180 ? ? 'expression tag' -11 16 1 5FBK LEU A 17 ? UNP P41180 ? ? 'expression tag' -10 17 1 5FBK ALA A 18 ? UNP P41180 ? ? 'expression tag' -9 18 1 5FBK PHE A 19 ? UNP P41180 ? ? 'expression tag' -8 19 1 5FBK SER A 20 ? UNP P41180 ? ? 'expression tag' -7 20 1 5FBK VAL A 21 ? UNP P41180 ? ? 'expression tag' -6 21 1 5FBK SER A 22 ? UNP P41180 ? ? 'expression tag' -5 22 1 5FBK ALA A 23 ? UNP P41180 ? ? 'expression tag' -4 23 1 5FBK LYS A 24 ? UNP P41180 ? ? 'expression tag' -3 24 1 5FBK SER A 25 ? UNP P41180 ? ? 'expression tag' -2 25 1 5FBK MET A 26 ? UNP P41180 ? ? 'expression tag' -1 26 1 5FBK HIS A 27 ? UNP P41180 ? ? 'expression tag' 0 27 1 5FBK HIS A 28 ? UNP P41180 ? ? 'expression tag' 1 28 1 5FBK HIS A 29 ? UNP P41180 ? ? 'expression tag' 2 29 1 5FBK HIS A 30 ? UNP P41180 ? ? 'expression tag' 3 30 1 5FBK HIS A 31 ? UNP P41180 ? ? 'expression tag' 4 31 1 5FBK HIS A 32 ? UNP P41180 ? ? 'expression tag' 5 32 1 5FBK HIS A 33 ? UNP P41180 ? ? 'expression tag' 6 33 1 5FBK HIS A 34 ? UNP P41180 ? ? 'expression tag' 7 34 1 5FBK SER A 35 ? UNP P41180 ? ? 'expression tag' 8 35 1 5FBK ALA A 36 ? UNP P41180 ? ? 'expression tag' 9 36 1 5FBK TRP A 37 ? UNP P41180 ? ? 'expression tag' 10 37 1 5FBK SER A 38 ? UNP P41180 ? ? 'expression tag' 11 38 1 5FBK HIS A 39 ? UNP P41180 ? ? 'expression tag' 12 39 1 5FBK PRO A 40 ? UNP P41180 ? ? 'expression tag' 13 40 1 5FBK GLN A 41 ? UNP P41180 ? ? 'expression tag' 14 41 1 5FBK PHE A 42 ? UNP P41180 ? ? 'expression tag' 15 42 1 5FBK GLU A 43 ? UNP P41180 ? ? 'expression tag' 16 43 1 5FBK LYS A 44 ? UNP P41180 ? ? 'expression tag' 17 44 1 5FBK GLU A 45 ? UNP P41180 ? ? 'expression tag' 18 45 1 5FBK PHE A 46 ? UNP P41180 ? ? 'expression tag' 19 46 2 5FBK MET B 1 ? UNP P41180 ? ? 'initiating methionine' -26 47 2 5FBK ARG B 2 ? UNP P41180 ? ? 'expression tag' -25 48 2 5FBK LEU B 3 ? UNP P41180 ? ? 'expression tag' -24 49 2 5FBK LEU B 4 ? UNP P41180 ? ? 'expression tag' -23 50 2 5FBK THR B 5 ? UNP P41180 ? ? 'expression tag' -22 51 2 5FBK ALA B 6 ? UNP P41180 ? ? 'expression tag' -21 52 2 5FBK LEU B 7 ? UNP P41180 ? ? 'expression tag' -20 53 2 5FBK PHE B 8 ? UNP P41180 ? ? 'expression tag' -19 54 2 5FBK ALA B 9 ? UNP P41180 ? ? 'expression tag' -18 55 2 5FBK TYR B 10 ? UNP P41180 ? ? 'expression tag' -17 56 2 5FBK PHE B 11 ? UNP P41180 ? ? 'expression tag' -16 57 2 5FBK ILE B 12 ? UNP P41180 ? ? 'expression tag' -15 58 2 5FBK VAL B 13 ? UNP P41180 ? ? 'expression tag' -14 59 2 5FBK ALA B 14 ? UNP P41180 ? ? 'expression tag' -13 60 2 5FBK LEU B 15 ? UNP P41180 ? ? 'expression tag' -12 61 2 5FBK ILE B 16 ? UNP P41180 ? ? 'expression tag' -11 62 2 5FBK LEU B 17 ? UNP P41180 ? ? 'expression tag' -10 63 2 5FBK ALA B 18 ? UNP P41180 ? ? 'expression tag' -9 64 2 5FBK PHE B 19 ? UNP P41180 ? ? 'expression tag' -8 65 2 5FBK SER B 20 ? UNP P41180 ? ? 'expression tag' -7 66 2 5FBK VAL B 21 ? UNP P41180 ? ? 'expression tag' -6 67 2 5FBK SER B 22 ? UNP P41180 ? ? 'expression tag' -5 68 2 5FBK ALA B 23 ? UNP P41180 ? ? 'expression tag' -4 69 2 5FBK LYS B 24 ? UNP P41180 ? ? 'expression tag' -3 70 2 5FBK SER B 25 ? UNP P41180 ? ? 'expression tag' -2 71 2 5FBK MET B 26 ? UNP P41180 ? ? 'expression tag' -1 72 2 5FBK HIS B 27 ? UNP P41180 ? ? 'expression tag' 0 73 2 5FBK HIS B 28 ? UNP P41180 ? ? 'expression tag' 1 74 2 5FBK HIS B 29 ? UNP P41180 ? ? 'expression tag' 2 75 2 5FBK HIS B 30 ? UNP P41180 ? ? 'expression tag' 3 76 2 5FBK HIS B 31 ? UNP P41180 ? ? 'expression tag' 4 77 2 5FBK HIS B 32 ? UNP P41180 ? ? 'expression tag' 5 78 2 5FBK HIS B 33 ? UNP P41180 ? ? 'expression tag' 6 79 2 5FBK HIS B 34 ? UNP P41180 ? ? 'expression tag' 7 80 2 5FBK SER B 35 ? UNP P41180 ? ? 'expression tag' 8 81 2 5FBK ALA B 36 ? UNP P41180 ? ? 'expression tag' 9 82 2 5FBK TRP B 37 ? UNP P41180 ? ? 'expression tag' 10 83 2 5FBK SER B 38 ? UNP P41180 ? ? 'expression tag' 11 84 2 5FBK HIS B 39 ? UNP P41180 ? ? 'expression tag' 12 85 2 5FBK PRO B 40 ? UNP P41180 ? ? 'expression tag' 13 86 2 5FBK GLN B 41 ? UNP P41180 ? ? 'expression tag' 14 87 2 5FBK PHE B 42 ? UNP P41180 ? ? 'expression tag' 15 88 2 5FBK GLU B 43 ? UNP P41180 ? ? 'expression tag' 16 89 2 5FBK LYS B 44 ? UNP P41180 ? ? 'expression tag' 17 90 2 5FBK GLU B 45 ? UNP P41180 ? ? 'expression tag' 18 91 2 5FBK PHE B 46 ? UNP P41180 ? ? 'expression tag' 19 92 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BCT non-polymer . 'BICARBONATE ION' ? 'C H O3 -1' 61.017 CL non-polymer . 'CHLORIDE ION' ? 'Cl -1' 35.453 CSO 'L-peptide linking' n S-HYDROXYCYSTEINE ? 'C3 H7 N O3 S' 137.158 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MG non-polymer . 'MAGNESIUM ION' ? 'Mg 2' 24.305 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 TCR 'L-peptide linking' n CYCLOMETHYLTRYPTOPHAN ? 'C12 H12 N2 O2' 216.236 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5FBK _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.51 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 51.02 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH 7.0 _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 294 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '10% PEG 8000, 200 mM MgCl2, 10 mM CaCl2 and 100 mM Tris-HCl' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'MARMOSAIC 300 mm CCD' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2015-06-21 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9785 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'APS BEAMLINE 21-ID-D' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.9785 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline 21-ID-D _diffrn_source.pdbx_synchrotron_site APS # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5FBK _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 2.100 _reflns.d_resolution_low 40.000 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 74547 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 100.000 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 3.800 _reflns.pdbx_Rmerge_I_obs 0.072 _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI 18.063 _reflns.pdbx_netI_over_sigmaI 9.000 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared 0.975 _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all 0.076 _reflns.pdbx_Rpim_I_all 0.043 _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all 284906 _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # loop_ _reflns_shell.d_res_high _reflns_shell.d_res_low _reflns_shell.meanI_over_sigI_all _reflns_shell.meanI_over_sigI_obs _reflns_shell.number_measured_all _reflns_shell.number_measured_obs _reflns_shell.number_possible _reflns_shell.number_unique_all _reflns_shell.number_unique_obs _reflns_shell.percent_possible_all _reflns_shell.percent_possible_obs _reflns_shell.Rmerge_F_all _reflns_shell.Rmerge_F_obs _reflns_shell.Rmerge_I_all _reflns_shell.Rmerge_I_obs _reflns_shell.meanI_over_sigI_gt _reflns_shell.meanI_over_uI_all _reflns_shell.meanI_over_uI_gt _reflns_shell.number_measured_gt _reflns_shell.number_unique_gt _reflns_shell.percent_possible_gt _reflns_shell.Rmerge_F_gt _reflns_shell.Rmerge_I_gt _reflns_shell.pdbx_redundancy _reflns_shell.pdbx_Rsym_value _reflns_shell.pdbx_chi_squared _reflns_shell.pdbx_netI_over_sigmaI_all _reflns_shell.pdbx_netI_over_sigmaI_obs _reflns_shell.pdbx_Rrim_I_all _reflns_shell.pdbx_Rpim_I_all _reflns_shell.pdbx_rejects _reflns_shell.pdbx_ordinal _reflns_shell.pdbx_diffrn_id _reflns_shell.pdbx_CC_half _reflns_shell.pdbx_R_split 2.100 2.180 ? ? ? ? ? 7381 ? 100.000 ? ? ? ? 0.913 ? ? ? ? ? ? ? ? 3.800 ? 0.915 ? ? ? 0.541 0 1 1 0.631 ? 2.180 2.260 ? ? ? ? ? 7435 ? 100.000 ? ? ? ? 0.663 ? ? ? ? ? ? ? ? 3.800 ? 0.939 ? ? 0.771 0.393 0 2 1 0.762 ? 2.260 2.370 ? ? ? ? ? 7421 ? 100.000 ? ? ? ? 0.475 ? ? ? ? ? ? ? ? 3.800 ? 0.932 ? ? 0.552 0.281 0 3 1 0.862 ? 2.370 2.490 ? ? ? ? ? 7408 ? 100.000 ? ? ? ? 0.340 ? ? ? ? ? ? ? ? 3.800 ? 0.965 ? ? 0.395 0.201 0 4 1 0.918 ? 2.490 2.650 ? ? ? ? ? 7427 ? 100.000 ? ? ? ? 0.240 ? ? ? ? ? ? ? ? 3.800 ? 1.001 ? ? 0.279 0.142 0 5 1 0.959 ? 2.650 2.850 ? ? ? ? ? 7456 ? 100.000 ? ? ? ? 0.150 ? ? ? ? ? ? ? ? 3.800 ? 1.037 ? ? 0.175 0.089 0 6 1 0.982 ? 2.850 3.140 ? ? ? ? ? 7465 ? 100.000 ? ? ? ? 0.091 ? ? ? ? ? ? ? ? 3.800 ? 0.964 ? ? 0.106 0.054 0 7 1 0.991 ? 3.140 3.590 ? ? ? ? ? 7452 ? 100.000 ? ? ? ? 0.068 ? ? ? ? ? ? ? ? 3.800 ? 0.990 ? ? 0.079 0.040 0 8 1 0.994 ? 3.590 4.520 ? ? ? ? ? 7513 ? 99.900 ? ? ? ? 0.041 ? ? ? ? ? ? ? ? 3.800 ? 0.970 ? ? 0.047 0.024 0 9 1 0.998 ? 4.520 40.000 ? ? ? ? ? 7589 ? 99.800 ? ? ? ? 0.029 ? ? ? ? ? ? ? ? 3.700 ? 1.040 ? ? 0.034 0.017 0 10 1 0.998 ? # _refine.aniso_B[1][1] 0.0300 _refine.aniso_B[1][2] -0.0000 _refine.aniso_B[1][3] -1.7000 _refine.aniso_B[2][2] 1.4500 _refine.aniso_B[2][3] -0.0000 _refine.aniso_B[3][3] -0.4900 _refine.B_iso_max 123.010 _refine.B_iso_mean 44.9870 _refine.B_iso_min 21.880 _refine.correlation_coeff_Fo_to_Fc 0.9630 _refine.correlation_coeff_Fo_to_Fc_free 0.9490 _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY' _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 5FBK _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 2.1000 _refine.ls_d_res_low 37.7700 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 72544 _refine.ls_number_reflns_R_free 2000 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 99.7800 _refine.ls_percent_reflns_R_free 2.7000 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.1910 _refine.ls_R_factor_R_free 0.2227 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.1901 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details MASK _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.000 _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_method_to_determine_struct ? _refine.pdbx_starting_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R 0.1770 _refine.pdbx_overall_ESU_R_Free 0.1560 _refine.pdbx_solvent_vdw_probe_radii 1.2000 _refine.pdbx_solvent_ion_probe_radii 0.8000 _refine.pdbx_solvent_shrinkage_radii 0.8000 _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B 5.3350 _refine.overall_SU_ML 0.1340 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_hist.cycle_id final _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.d_res_high 2.1000 _refine_hist.d_res_low 37.7700 _refine_hist.pdbx_number_atoms_ligand 161 _refine_hist.number_atoms_solvent 323 _refine_hist.number_atoms_total 7901 _refine_hist.pdbx_number_residues_total 954 _refine_hist.pdbx_B_iso_mean_ligand 64.88 _refine_hist.pdbx_B_iso_mean_solvent 46.14 _refine_hist.pdbx_number_atoms_protein 7417 _refine_hist.pdbx_number_atoms_nucleic_acid 0 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.criterion _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.rejects _refine_ls_restr.type _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' ? 0.010 0.019 7766 ? r_bond_refined_d ? ? 'X-RAY DIFFRACTION' ? 0.004 0.020 7093 ? r_bond_other_d ? ? 'X-RAY DIFFRACTION' ? 1.379 1.960 10569 ? r_angle_refined_deg ? ? 'X-RAY DIFFRACTION' ? 0.981 3.000 16207 ? r_angle_other_deg ? ? 'X-RAY DIFFRACTION' ? 5.807 5.000 949 ? r_dihedral_angle_1_deg ? ? 'X-RAY DIFFRACTION' ? 30.525 24.029 350 ? r_dihedral_angle_2_deg ? ? 'X-RAY DIFFRACTION' ? 16.497 15.000 1174 ? r_dihedral_angle_3_deg ? ? 'X-RAY DIFFRACTION' ? 20.173 15.000 38 ? r_dihedral_angle_4_deg ? ? 'X-RAY DIFFRACTION' ? 0.079 0.200 1180 ? r_chiral_restr ? ? 'X-RAY DIFFRACTION' ? 0.006 0.020 8837 ? r_gen_planes_refined ? ? 'X-RAY DIFFRACTION' ? 0.003 0.020 1853 ? r_gen_planes_other ? ? 'X-RAY DIFFRACTION' ? 2.666 4.420 3817 ? r_mcbond_it ? ? 'X-RAY DIFFRACTION' ? 2.666 4.421 3816 ? r_mcbond_other ? ? 'X-RAY DIFFRACTION' ? 4.109 6.617 4759 ? r_mcangle_it ? ? # loop_ _refine_ls_restr_ncs.pdbx_ordinal _refine_ls_restr_ncs.pdbx_refine_id _refine_ls_restr_ncs.pdbx_ens_id _refine_ls_restr_ncs.dom_id _refine_ls_restr_ncs.pdbx_type _refine_ls_restr_ncs.pdbx_auth_asym_id _refine_ls_restr_ncs.pdbx_number _refine_ls_restr_ncs.rms_dev_position _refine_ls_restr_ncs.weight_position _refine_ls_restr_ncs.ncs_model_details _refine_ls_restr_ncs.rms_dev_B_iso _refine_ls_restr_ncs.weight_B_iso 1 'X-RAY DIFFRACTION' 1 1 'interatomic distance' A 25787 0.110 0.050 ? ? ? 2 'X-RAY DIFFRACTION' 1 2 'interatomic distance' B 25787 0.110 0.050 ? ? ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.d_res_high 2.0960 _refine_ls_shell.d_res_low 2.1500 _refine_ls_shell.number_reflns_all 5325 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.number_reflns_R_free 143 _refine_ls_shell.number_reflns_R_work 5182 _refine_ls_shell.percent_reflns_obs 97.8000 _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_obs ? _refine_ls_shell.R_factor_R_free 0.3140 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.R_factor_R_work 0.3050 _refine_ls_shell.redundancy_reflns_all ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.wR_factor_all ? _refine_ls_shell.wR_factor_obs ? _refine_ls_shell.wR_factor_R_free ? _refine_ls_shell.wR_factor_R_work ? _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.pdbx_phase_error ? _refine_ls_shell.pdbx_fsc_work ? _refine_ls_shell.pdbx_fsc_free ? # loop_ _struct_ncs_dom.pdbx_ens_id _struct_ncs_dom.id _struct_ncs_dom.details 1 1 A 1 2 B # loop_ _struct_ncs_dom_lim.pdbx_ens_id _struct_ncs_dom_lim.dom_id _struct_ncs_dom_lim.pdbx_component_id _struct_ncs_dom_lim.pdbx_refine_code _struct_ncs_dom_lim.beg_auth_asym_id _struct_ncs_dom_lim.beg_auth_seq_id _struct_ncs_dom_lim.end_auth_asym_id _struct_ncs_dom_lim.end_auth_seq_id _struct_ncs_dom_lim.selection_details _struct_ncs_dom_lim.beg_label_asym_id _struct_ncs_dom_lim.beg_label_comp_id _struct_ncs_dom_lim.beg_label_seq_id _struct_ncs_dom_lim.beg_label_alt_id _struct_ncs_dom_lim.end_label_asym_id _struct_ncs_dom_lim.end_label_comp_id _struct_ncs_dom_lim.end_label_seq_id _struct_ncs_dom_lim.end_label_alt_id 1 1 0 0 A 22 A 531 ? ? ? ? ? ? ? ? ? 1 2 0 0 B 22 B 531 ? ? ? ? ? ? ? ? ? # _struct_ncs_ens.id 1 _struct_ncs_ens.details ? # _struct.entry_id 5FBK _struct.title 'Crystal structure of the extracellular domain of human calcium sensing receptor' _struct.pdbx_descriptor 'Extracellular calcium-sensing receptor' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5FBK _struct_keywords.text 'membrane protein, G-protein coupled receptor, ectodomain, SIGNALING PROTEIN' _struct_keywords.pdbx_keywords 'SIGNALING PROTEIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 3 ? E N N 3 ? F N N 3 ? G N N 3 ? H N N 4 ? I N N 4 ? J N N 4 ? K N N 5 ? L N N 6 ? M N N 2 ? N N N 3 ? O N N 3 ? P N N 3 ? Q N N 3 ? R N N 4 ? S N N 4 ? T N N 4 ? U N N 5 ? V N N 6 ? W N N 6 ? X N N 7 ? Y N N 7 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 ASN A 91 ? SER A 110 ? ASN A 64 SER A 83 1 ? 20 HELX_P HELX_P2 AA2 THR A 130 ? VAL A 142 ? THR A 103 VAL A 115 1 ? 13 HELX_P HELX_P3 AA3 VAL A 142 ? ASN A 151 ? VAL A 115 ASN A 124 1 ? 10 HELX_P HELX_P4 AA4 ASN A 151 ? CYS A 156 ? ASN A 124 CYS A 129 1 ? 6 HELX_P HELX_P5 AA5 GLY A 173 ? PHE A 187 ? GLY A 146 PHE A 160 1 ? 15 HELX_P HELX_P6 AA6 SER A 198 ? ASN A 203 ? SER A 171 ASN A 176 5 ? 6 HELX_P HELX_P7 AA7 ASP A 217 ? PHE A 231 ? ASP A 190 PHE A 204 1 ? 15 HELX_P HELX_P8 AA8 TYR A 245 ? ARG A 260 ? TYR A 218 ARG A 233 1 ? 16 HELX_P HELX_P9 AA9 ASP A 275 ? SER A 289 ? ASP A 248 SER A 262 1 ? 15 HELX_P HELX_P10 AB1 SER A 299 ? ARG A 313 ? SER A 272 ARG A 286 1 ? 15 HELX_P HELX_P11 AB2 SER A 323 ? SER A 328 ? SER A 296 SER A 301 1 ? 6 HELX_P HELX_P12 AB3 MET A 334 ? GLN A 336 ? MET A 307 GLN A 309 5 ? 3 HELX_P HELX_P13 AB4 TYR A 337 ? GLY A 342 ? TYR A 310 GLY A 315 1 ? 6 HELX_P HELX_P14 AB5 GLY A 356 ? LYS A 363 ? GLY A 329 LYS A 336 1 ? 8 HELX_P HELX_P15 AB6 PHE A 374 ? ASN A 384 ? PHE A 347 ASN A 357 1 ? 11 HELX_P HELX_P16 AB7 ASN A 427 ? VAL A 431 ? ASN A 400 VAL A 404 5 ? 5 HELX_P HELX_P17 AB8 ARG A 442 ? THR A 463 ? ARG A 415 THR A 436 1 ? 22 HELX_P HELX_P18 AB9 PHE A 471 ? SER A 475 ? PHE A 444 SER A 448 5 ? 5 HELX_P HELX_P19 AC1 ASP A 478 ? VAL A 482 ? ASP A 451 VAL A 455 5 ? 5 HELX_P HELX_P20 AC2 GLU A 483 ? HIS A 493 ? GLU A 456 HIS A 466 1 ? 11 HELX_P HELX_P21 AC3 GLU A 552 ? ILE A 555 ? GLU A 525 ILE A 528 5 ? 4 HELX_P HELX_P22 AC4 LEU A 556 ? PHE A 560 ? LEU A 529 PHE A 533 5 ? 5 HELX_P HELX_P23 AC5 ASN B 91 ? SER B 110 ? ASN B 64 SER B 83 1 ? 20 HELX_P HELX_P24 AC6 THR B 130 ? VAL B 142 ? THR B 103 VAL B 115 1 ? 13 HELX_P HELX_P25 AC7 VAL B 142 ? ASP B 148 ? VAL B 115 ASP B 121 1 ? 7 HELX_P HELX_P26 AC8 GLY B 173 ? GLY B 185 ? GLY B 146 GLY B 158 1 ? 13 HELX_P HELX_P27 AC9 LEU B 186 ? TYR B 188 ? LEU B 159 TYR B 161 5 ? 3 HELX_P HELX_P28 AD1 SER B 198 ? ASN B 203 ? SER B 171 ASN B 176 5 ? 6 HELX_P HELX_P29 AD2 ASN B 216 ? PHE B 231 ? ASN B 189 PHE B 204 1 ? 16 HELX_P HELX_P30 AD3 TYR B 245 ? ARG B 260 ? TYR B 218 ARG B 233 1 ? 16 HELX_P HELX_P31 AD4 ASP B 275 ? SER B 289 ? ASP B 248 SER B 262 1 ? 15 HELX_P HELX_P32 AD5 SER B 299 ? ARG B 313 ? SER B 272 ARG B 286 1 ? 15 HELX_P HELX_P33 AD6 SER B 323 ? SER B 328 ? SER B 296 SER B 301 1 ? 6 HELX_P HELX_P34 AD7 MET B 334 ? GLN B 336 ? MET B 307 GLN B 309 5 ? 3 HELX_P HELX_P35 AD8 TYR B 337 ? GLY B 342 ? TYR B 310 GLY B 315 1 ? 6 HELX_P HELX_P36 AD9 GLY B 356 ? LYS B 363 ? GLY B 329 LYS B 336 1 ? 8 HELX_P HELX_P37 AE1 PHE B 374 ? ASN B 384 ? PHE B 347 ASN B 357 1 ? 11 HELX_P HELX_P38 AE2 ASN B 427 ? VAL B 431 ? ASN B 400 VAL B 404 5 ? 5 HELX_P HELX_P39 AE3 ARG B 442 ? THR B 463 ? ARG B 415 THR B 436 1 ? 22 HELX_P HELX_P40 AE4 PHE B 471 ? SER B 475 ? PHE B 444 SER B 448 5 ? 5 HELX_P HELX_P41 AE5 ASP B 478 ? VAL B 482 ? ASP B 451 VAL B 455 5 ? 5 HELX_P HELX_P42 AE6 GLU B 483 ? HIS B 493 ? GLU B 456 HIS B 466 1 ? 11 HELX_P HELX_P43 AE7 GLU B 552 ? ILE B 555 ? GLU B 525 ILE B 528 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 87 SG ? ? ? 1_555 A CYS 128 SG ? ? A CYS 60 A CYS 101 1_555 ? ? ? ? ? ? ? 2.033 ? disulf2 disulf ? ? A CYS 385 SG ? ? ? 1_555 A CYS 422 SG ? ? A CYS 358 A CYS 395 1_555 ? ? ? ? ? ? ? 2.037 ? disulf3 disulf ? ? A CYS 464 SG ? ? ? 1_555 A CYS 476 SG ? ? A CYS 437 A CYS 449 1_555 ? ? ? ? ? ? ? 2.065 ? disulf4 disulf ? ? B CYS 87 SG ? ? ? 1_555 B CYS 128 SG ? ? B CYS 60 B CYS 101 1_555 ? ? ? ? ? ? ? 2.018 ? disulf5 disulf ? ? B CYS 385 SG ? ? ? 1_555 B CYS 422 SG ? ? B CYS 358 B CYS 395 1_555 ? ? ? ? ? ? ? 2.034 ? disulf6 disulf ? ? B CYS 464 SG ? ? ? 1_555 B CYS 476 SG ? ? B CYS 437 B CYS 449 1_555 ? ? ? ? ? ? ? 2.115 ? metalc1 metalc ? ? A ILE 108 O ? ? ? 1_555 L MG . MG ? ? A ILE 81 A MG 610 1_555 ? ? ? ? ? ? ? 2.683 ? metalc2 metalc ? ? A SER 111 O ? ? ? 1_555 L MG . MG ? ? A SER 84 A MG 610 1_555 ? ? ? ? ? ? ? 2.859 ? metalc3 metalc ? ? A LEU 114 O ? ? ? 1_555 L MG . MG ? ? A LEU 87 A MG 610 1_555 ? ? ? ? ? ? ? 2.211 ? covale1 covale both ? A ILE 262 C ? ? ? 1_555 A CSO 263 N ? ? A ILE 235 A CSO 236 1_555 ? ? ? ? ? ? ? 1.330 ? covale2 covale both ? A CSO 263 C ? ? ? 1_555 A ILE 264 N ? ? A CSO 236 A ILE 237 1_555 ? ? ? ? ? ? ? 1.332 ? covale3 covale one ? A ASN 288 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 261 A NAG 605 1_555 ? ? ? ? ? ? ? 1.444 ? covale4 covale one ? A ASN 314 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 287 A NAG 604 1_555 ? ? ? ? ? ? ? 1.447 ? covale5 covale one ? A ASN 495 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 468 A NAG 603 1_555 ? ? ? ? ? ? ? 1.463 ? covale6 covale both ? A GLU 508 C ? ? ? 1_555 A CSO 509 N ? ? A GLU 481 A CSO 482 1_555 ? ? ? ? ? ? ? 1.343 ? covale7 covale both ? A CSO 509 C ? ? ? 1_555 A GLY 510 N ? ? A CSO 482 A GLY 483 1_555 ? ? ? ? ? ? ? 1.333 ? covale8 covale one ? A ASN 515 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 488 A NAG 602 1_555 ? ? ? ? ? ? ? 1.465 ? metalc4 metalc ? ? B ILE 108 O ? ? ? 1_555 W MG . MG ? ? B ILE 81 B MG 611 1_555 ? ? ? ? ? ? ? 2.485 ? metalc5 metalc ? ? B SER 111 O ? ? ? 1_555 W MG . MG ? ? B SER 84 B MG 611 1_555 ? ? ? ? ? ? ? 2.823 ? metalc6 metalc ? ? B LEU 114 O ? ? ? 1_555 W MG . MG ? ? B LEU 87 B MG 611 1_555 ? ? ? ? ? ? ? 2.299 ? covale9 covale both ? B ILE 262 C ? ? ? 1_555 B CSO 263 N ? ? B ILE 235 B CSO 236 1_555 ? ? ? ? ? ? ? 1.335 ? covale10 covale both ? B CSO 263 C ? ? ? 1_555 B ILE 264 N ? ? B CSO 236 B ILE 237 1_555 ? ? ? ? ? ? ? 1.331 ? metalc7 metalc ? ? B SER 267 O ? ? ? 1_555 V MG . MG ? ? B SER 240 B MG 610 1_555 ? ? ? ? ? ? ? 2.168 ? metalc8 metalc ? ? B SER 267 OG ? ? ? 1_555 V MG . MG ? ? B SER 240 B MG 610 1_555 ? ? ? ? ? ? ? 2.180 ? covale11 covale one ? B ASN 288 ND2 ? ? ? 1_555 Q NAG . C1 ? ? B ASN 261 B NAG 605 1_555 ? ? ? ? ? ? ? 1.452 ? covale12 covale one ? B ASN 314 ND2 ? ? ? 1_555 P NAG . C1 ? ? B ASN 287 B NAG 604 1_555 ? ? ? ? ? ? ? 1.449 ? covale13 covale one ? B ASN 495 ND2 ? ? ? 1_555 O NAG . C1 ? ? B ASN 468 B NAG 603 1_555 ? ? ? ? ? ? ? 1.445 ? covale14 covale both ? B GLU 508 C ? ? ? 1_555 B CSO 509 N ? ? B GLU 481 B CSO 482 1_555 ? ? ? ? ? ? ? 1.330 ? covale15 covale both ? B CSO 509 C ? ? ? 1_555 B GLY 510 N ? ? B CSO 482 B GLY 483 1_555 ? ? ? ? ? ? ? 1.331 ? covale16 covale one ? B ASN 515 ND2 ? ? ? 1_555 N NAG . C1 ? ? B ASN 488 B NAG 602 1_555 ? ? ? ? ? ? ? 1.447 ? metalc9 metalc ? ? L MG . MG ? ? ? 1_555 X HOH . O ? ? A MG 610 A HOH 732 1_555 ? ? ? ? ? ? ? 2.528 ? metalc10 metalc ? ? V MG . MG ? ? ? 1_555 Y HOH . O ? ? B MG 610 B HOH 817 1_555 ? ? ? ? ? ? ? 2.125 ? metalc11 metalc ? ? V MG . MG ? ? ? 1_555 Y HOH . O ? ? B MG 610 B HOH 838 1_555 ? ? ? ? ? ? ? 2.221 ? metalc12 metalc ? ? V MG . MG ? ? ? 1_555 X HOH . O ? ? B MG 610 A HOH 740 1_555 ? ? ? ? ? ? ? 2.085 ? metalc13 metalc ? ? V MG . MG ? ? ? 1_555 Y HOH . O ? ? B MG 610 B HOH 800 1_555 ? ? ? ? ? ? ? 2.050 ? metalc14 metalc ? ? W MG . MG ? ? ? 1_555 Y HOH . O ? ? B MG 611 B HOH 773 1_555 ? ? ? ? ? ? ? 2.308 ? metalc15 metalc ? ? W MG . MG ? ? ? 1_555 Y HOH . O ? ? B MG 611 B HOH 820 1_555 ? ? ? ? ? ? ? 2.485 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLY 170 A . ? GLY 143 A ALA 171 A ? ALA 144 A 1 -5.13 2 VAL 564 A . ? VAL 537 A PRO 565 A ? PRO 538 A 1 -13.74 3 GLY 170 B . ? GLY 143 B ALA 171 B ? ALA 144 B 1 -5.07 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 6 ? AA2 ? 2 ? AA3 ? 8 ? AA4 ? 2 ? AA5 ? 6 ? AA6 ? 2 ? AA7 ? 8 ? AA8 ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? parallel AA1 3 4 ? parallel AA1 4 5 ? parallel AA1 5 6 ? parallel AA2 1 2 ? anti-parallel AA3 1 2 ? parallel AA3 2 3 ? parallel AA3 3 4 ? parallel AA3 4 5 ? parallel AA3 5 6 ? anti-parallel AA3 6 7 ? anti-parallel AA3 7 8 ? anti-parallel AA4 1 2 ? anti-parallel AA5 1 2 ? anti-parallel AA5 2 3 ? parallel AA5 3 4 ? parallel AA5 4 5 ? parallel AA5 5 6 ? parallel AA6 1 2 ? anti-parallel AA7 1 2 ? parallel AA7 2 3 ? parallel AA7 3 4 ? parallel AA7 4 5 ? parallel AA7 5 6 ? anti-parallel AA7 6 7 ? anti-parallel AA7 7 8 ? anti-parallel AA8 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 ALA A 53 ? LYS A 55 ? ALA A 26 LYS A 28 AA1 2 LEU A 120 ? ASP A 126 ? LEU A 93 ASP A 99 AA1 3 ILE A 59 ? PHE A 65 ? ILE A 32 PHE A 38 AA1 4 THR A 165 ? VAL A 169 ? THR A 138 VAL A 142 AA1 5 GLN A 191 ? SER A 193 ? GLN A 164 SER A 166 AA1 6 PHE A 210 ? ARG A 212 ? PHE A 183 ARG A 185 AA2 1 HIS A 68 ? VAL A 71 ? HIS A 41 VAL A 44 AA2 2 CYS A 87 ? TYR A 90 ? CYS A 60 TYR A 63 AA3 1 ILE A 264 ? ILE A 270 ? ILE A 237 ILE A 243 AA3 2 VAL A 236 ? ALA A 241 ? VAL A 209 ALA A 214 AA3 3 VAL A 293 ? PHE A 297 ? VAL A 266 PHE A 270 AA3 4 ILE A 319 ? ALA A 322 ? ILE A 292 ALA A 295 AA3 5 ILE A 345 ? LEU A 349 ? ILE A 318 LEU A 322 AA3 6 TYR A 516 ? LEU A 523 ? TYR A 489 LEU A 496 AA3 7 ILE A 530 ? TYR A 538 ? ILE A 503 TYR A 511 AA3 8 LEU A 548 ? ILE A 550 ? LEU A 521 ILE A 523 AA4 1 ASN A 495 ? THR A 497 ? ASN A 468 THR A 470 AA4 2 GLN A 503 ? THR A 505 ? GLN A 476 THR A 478 AA5 1 ALA B 53 ? LYS B 55 ? ALA B 26 LYS B 28 AA5 2 LEU B 120 ? ASP B 126 ? LEU B 93 ASP B 99 AA5 3 ILE B 59 ? PHE B 65 ? ILE B 32 PHE B 38 AA5 4 THR B 165 ? VAL B 169 ? THR B 138 VAL B 142 AA5 5 GLN B 191 ? SER B 193 ? GLN B 164 SER B 166 AA5 6 PHE B 210 ? ARG B 212 ? PHE B 183 ARG B 185 AA6 1 HIS B 68 ? VAL B 71 ? HIS B 41 VAL B 44 AA6 2 CYS B 87 ? TYR B 90 ? CYS B 60 TYR B 63 AA7 1 CSO B 263 ? ILE B 270 ? CSO B 236 ILE B 243 AA7 2 TRP B 235 ? ALA B 241 ? TRP B 208 ALA B 214 AA7 3 VAL B 293 ? PHE B 297 ? VAL B 266 PHE B 270 AA7 4 ILE B 319 ? ALA B 322 ? ILE B 292 ALA B 295 AA7 5 ILE B 345 ? LEU B 349 ? ILE B 318 LEU B 322 AA7 6 TYR B 516 ? LEU B 523 ? TYR B 489 LEU B 496 AA7 7 ILE B 530 ? TYR B 538 ? ILE B 503 TYR B 511 AA7 8 LEU B 548 ? ILE B 550 ? LEU B 521 ILE B 523 AA8 1 PHE B 496 ? THR B 497 ? PHE B 469 THR B 470 AA8 2 GLN B 503 ? VAL B 504 ? GLN B 476 VAL B 477 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N ALA A 53 ? N ALA A 26 O ILE A 124 ? O ILE A 97 AA1 2 3 O GLY A 121 ? O GLY A 94 N ILE A 59 ? N ILE A 32 AA1 3 4 N GLY A 62 ? N GLY A 35 O ALA A 167 ? O ALA A 140 AA1 4 5 N VAL A 168 ? N VAL A 141 O VAL A 192 ? O VAL A 165 AA1 5 6 N GLN A 191 ? N GLN A 164 O LEU A 211 ? O LEU A 184 AA2 1 2 N PHE A 69 ? N PHE A 42 O ARG A 89 ? O ARG A 62 AA3 1 2 O ASP A 265 ? O ASP A 238 N VAL A 236 ? N VAL A 209 AA3 2 3 N GLY A 237 ? N GLY A 210 O VAL A 295 ? O VAL A 268 AA3 3 4 N VAL A 296 ? N VAL A 269 O LEU A 321 ? O LEU A 294 AA3 4 5 N TRP A 320 ? N TRP A 293 O ILE A 345 ? O ILE A 318 AA3 5 6 N ALA A 348 ? N ALA A 321 O SER A 517 ? O SER A 490 AA3 6 7 N HIS A 522 ? N HIS A 495 O VAL A 531 ? O VAL A 504 AA3 7 8 N TYR A 537 ? N TYR A 510 O PHE A 549 ? O PHE A 522 AA4 1 2 N PHE A 496 ? N PHE A 469 O VAL A 504 ? O VAL A 477 AA5 1 2 N ALA B 53 ? N ALA B 26 O ILE B 124 ? O ILE B 97 AA5 2 3 O PHE B 125 ? O PHE B 98 N GLY B 63 ? N GLY B 36 AA5 3 4 N GLY B 62 ? N GLY B 35 O ALA B 167 ? O ALA B 140 AA5 4 5 N VAL B 168 ? N VAL B 141 O VAL B 192 ? O VAL B 165 AA5 5 6 N GLN B 191 ? N GLN B 164 O LEU B 211 ? O LEU B 184 AA6 1 2 N PHE B 69 ? N PHE B 42 O ARG B 89 ? O ARG B 62 AA7 1 2 O ASP B 265 ? O ASP B 238 N VAL B 236 ? N VAL B 209 AA7 2 3 N GLY B 237 ? N GLY B 210 O VAL B 295 ? O VAL B 268 AA7 3 4 N ILE B 294 ? N ILE B 267 O ILE B 319 ? O ILE B 292 AA7 4 5 N ALA B 322 ? N ALA B 295 O ILE B 345 ? O ILE B 318 AA7 5 6 N ALA B 348 ? N ALA B 321 O SER B 517 ? O SER B 490 AA7 6 7 N HIS B 522 ? N HIS B 495 O VAL B 531 ? O VAL B 504 AA7 7 8 N TYR B 537 ? N TYR B 510 O PHE B 549 ? O PHE B 522 AA8 1 2 N PHE B 496 ? N PHE B 469 O VAL B 504 ? O VAL B 477 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A TCR 601 ? 12 'binding site for residue TCR A 601' AC2 Software A CL 606 ? 6 'binding site for residue CL A 606' AC3 Software A CL 607 ? 7 'binding site for residue CL A 607' AC4 Software A CL 608 ? 3 'binding site for residue CL A 608' AC5 Software A BCT 609 ? 7 'binding site for residue BCT A 609' AC6 Software A MG 610 ? 5 'binding site for residue MG A 610' AC7 Software B TCR 601 ? 12 'binding site for residue TCR B 601' AC8 Software B CL 606 ? 5 'binding site for residue CL B 606' AC9 Software B CL 607 ? 7 'binding site for residue CL B 607' AD1 Software B CL 608 ? 2 'binding site for residue CL B 608' AD2 Software B BCT 609 ? 7 'binding site for residue BCT B 609' AD3 Software B MG 610 ? 5 'binding site for residue MG B 610' AD4 Software B MG 611 ? 7 'binding site for residue MG B 611' AD5 Software A NAG 605 ? 2 'binding site for Mono-Saccharide NAG A 605 bound to ASN A 261' AD6 Software A NAG 604 ? 2 'binding site for Mono-Saccharide NAG A 604 bound to ASN A 287' AD7 Software A NAG 603 ? 2 'binding site for Mono-Saccharide NAG A 603 bound to ASN A 468' AD8 Software A NAG 602 ? 6 'binding site for Mono-Saccharide NAG A 602 bound to ASN A 488' AD9 Software B NAG 605 ? 4 'binding site for Mono-Saccharide NAG B 605 bound to ASN B 261' AE1 Software B NAG 604 ? 1 'binding site for Mono-Saccharide NAG B 604 bound to ASN B 287' AE2 Software B NAG 603 ? 5 'binding site for Mono-Saccharide NAG B 603 bound to ASN B 468' AE3 Software B NAG 602 ? 7 'binding site for Mono-Saccharide NAG B 602 bound to ASN B 488' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 12 ARG A 93 ? ARG A 66 . ? 1_555 ? 2 AC1 12 TRP A 97 ? TRP A 70 . ? 1_555 ? 3 AC1 12 THR A 172 ? THR A 145 . ? 1_555 ? 4 AC1 12 GLY A 173 ? GLY A 146 . ? 1_555 ? 5 AC1 12 SER A 174 ? SER A 147 . ? 1_555 ? 6 AC1 12 ALA A 195 ? ALA A 168 . ? 1_555 ? 7 AC1 12 SER A 196 ? SER A 169 . ? 1_555 ? 8 AC1 12 SER A 197 ? SER A 170 . ? 1_555 ? 9 AC1 12 TYR A 245 ? TYR A 218 . ? 1_555 ? 10 AC1 12 GLU A 324 ? GLU A 297 . ? 1_555 ? 11 AC1 12 ALA A 325 ? ALA A 298 . ? 1_555 ? 12 AC1 12 HOH X . ? HOH A 709 . ? 1_555 ? 13 AC2 6 PHE A 65 ? PHE A 38 . ? 1_555 ? 14 AC2 6 PRO A 66 ? PRO A 39 . ? 1_555 ? 15 AC2 6 THR A 127 ? THR A 100 . ? 1_555 ? 16 AC2 6 ALA A 171 ? ALA A 144 . ? 1_555 ? 17 AC2 6 THR A 172 ? THR A 145 . ? 1_555 ? 18 AC2 6 HOH X . ? HOH A 827 . ? 1_555 ? 19 AC3 7 ALA A 181 ? ALA A 154 . ? 1_555 ? 20 AC3 7 GLY A 185 ? GLY A 158 . ? 1_555 ? 21 AC3 7 PHE A 207 ? PHE A 180 . ? 1_555 ? 22 AC3 7 LYS A 208 ? LYS A 181 . ? 1_555 ? 23 AC3 7 SER A 209 ? SER A 182 . ? 1_555 ? 24 AC3 7 PHE A 210 ? PHE A 183 . ? 1_555 ? 25 AC3 7 HOH X . ? HOH A 750 . ? 1_555 ? 26 AC4 3 SER A 329 ? SER A 302 . ? 1_555 ? 27 AC4 3 HOH X . ? HOH A 762 . ? 1_555 ? 28 AC4 3 HOH X . ? HOH A 824 . ? 1_555 ? 29 AC5 7 ARG A 93 ? ARG A 66 . ? 1_555 ? 30 AC5 7 ARG A 96 ? ARG A 69 . ? 1_555 ? 31 AC5 7 TRP A 97 ? TRP A 70 . ? 1_555 ? 32 AC5 7 LEU A 441 ? LEU A 414 . ? 1_555 ? 33 AC5 7 ARG A 442 ? ARG A 415 . ? 1_555 ? 34 AC5 7 ILE A 443 ? ILE A 416 . ? 1_555 ? 35 AC5 7 SER A 444 ? SER A 417 . ? 1_555 ? 36 AC6 5 ILE A 108 ? ILE A 81 . ? 1_555 ? 37 AC6 5 SER A 111 ? SER A 84 . ? 1_555 ? 38 AC6 5 LEU A 114 ? LEU A 87 . ? 1_555 ? 39 AC6 5 LEU A 115 ? LEU A 88 . ? 1_555 ? 40 AC6 5 HOH X . ? HOH A 732 . ? 1_555 ? 41 AC7 12 ARG B 93 ? ARG B 66 . ? 1_555 ? 42 AC7 12 TRP B 97 ? TRP B 70 . ? 1_555 ? 43 AC7 12 THR B 172 ? THR B 145 . ? 1_555 ? 44 AC7 12 GLY B 173 ? GLY B 146 . ? 1_555 ? 45 AC7 12 SER B 174 ? SER B 147 . ? 1_555 ? 46 AC7 12 ALA B 195 ? ALA B 168 . ? 1_555 ? 47 AC7 12 SER B 196 ? SER B 169 . ? 1_555 ? 48 AC7 12 SER B 197 ? SER B 170 . ? 1_555 ? 49 AC7 12 TYR B 245 ? TYR B 218 . ? 1_555 ? 50 AC7 12 GLU B 324 ? GLU B 297 . ? 1_555 ? 51 AC7 12 ALA B 325 ? ALA B 298 . ? 1_555 ? 52 AC7 12 HOH Y . ? HOH B 757 . ? 1_555 ? 53 AC8 5 PRO B 66 ? PRO B 39 . ? 1_555 ? 54 AC8 5 THR B 127 ? THR B 100 . ? 1_555 ? 55 AC8 5 ALA B 171 ? ALA B 144 . ? 1_555 ? 56 AC8 5 THR B 172 ? THR B 145 . ? 1_555 ? 57 AC8 5 HOH Y . ? HOH B 830 . ? 1_555 ? 58 AC9 7 ALA B 181 ? ALA B 154 . ? 1_555 ? 59 AC9 7 PHE B 207 ? PHE B 180 . ? 1_555 ? 60 AC9 7 LYS B 208 ? LYS B 181 . ? 1_555 ? 61 AC9 7 SER B 209 ? SER B 182 . ? 1_555 ? 62 AC9 7 PHE B 210 ? PHE B 183 . ? 1_555 ? 63 AC9 7 HOH Y . ? HOH B 745 . ? 1_555 ? 64 AC9 7 HOH Y . ? HOH B 758 . ? 1_555 ? 65 AD1 2 SER B 329 ? SER B 302 . ? 1_555 ? 66 AD1 2 HOH Y . ? HOH B 850 . ? 1_555 ? 67 AD2 7 ARG B 93 ? ARG B 66 . ? 1_555 ? 68 AD2 7 ARG B 96 ? ARG B 69 . ? 1_555 ? 69 AD2 7 TRP B 97 ? TRP B 70 . ? 1_555 ? 70 AD2 7 ARG B 442 ? ARG B 415 . ? 1_555 ? 71 AD2 7 ILE B 443 ? ILE B 416 . ? 1_555 ? 72 AD2 7 SER B 444 ? SER B 417 . ? 1_555 ? 73 AD2 7 HOH Y . ? HOH B 786 . ? 1_555 ? 74 AD3 5 HOH X . ? HOH A 740 . ? 1_555 ? 75 AD3 5 SER B 267 ? SER B 240 . ? 1_555 ? 76 AD3 5 HOH Y . ? HOH B 800 . ? 1_555 ? 77 AD3 5 HOH Y . ? HOH B 817 . ? 1_555 ? 78 AD3 5 HOH Y . ? HOH B 838 . ? 1_555 ? 79 AD4 7 ILE B 108 ? ILE B 81 . ? 1_555 ? 80 AD4 7 ASN B 109 ? ASN B 82 . ? 1_555 ? 81 AD4 7 SER B 111 ? SER B 84 . ? 1_555 ? 82 AD4 7 LEU B 114 ? LEU B 87 . ? 1_555 ? 83 AD4 7 LEU B 115 ? LEU B 88 . ? 1_555 ? 84 AD4 7 HOH Y . ? HOH B 773 . ? 1_555 ? 85 AD4 7 HOH Y . ? HOH B 820 . ? 1_555 ? 86 AD5 2 GLU A 284 ? GLU A 257 . ? 1_555 ? 87 AD5 2 ASN A 288 ? ASN A 261 . ? 1_555 ? 88 AD6 2 ASN A 314 ? ASN A 287 . ? 1_555 ? 89 AD6 2 ARG A 419 ? ARG A 392 . ? 2_556 ? 90 AD7 2 ASN A 495 ? ASN A 468 . ? 1_555 ? 91 AD7 2 THR A 505 ? THR A 478 . ? 1_555 ? 92 AD8 6 LYS A 350 ? LYS A 323 . ? 1_555 ? 93 AD8 6 GLU A 502 ? GLU A 475 . ? 1_555 ? 94 AD8 6 ASN A 515 ? ASN A 488 . ? 1_555 ? 95 AD8 6 ASN A 539 ? ASN A 512 . ? 1_555 ? 96 AD8 6 TYR A 541 ? TYR A 514 . ? 1_555 ? 97 AD8 6 HOH X . ? HOH A 781 . ? 1_555 ? 98 AD9 4 HIS B 281 ? HIS B 254 . ? 1_555 ? 99 AD9 4 GLU B 284 ? GLU B 257 . ? 1_555 ? 100 AD9 4 ASN B 288 ? ASN B 261 . ? 1_555 ? 101 AD9 4 HOH Y . ? HOH B 753 . ? 1_555 ? 102 AE1 1 ASN B 314 ? ASN B 287 . ? 1_555 ? 103 AE2 5 ASP B 460 ? ASP B 433 . ? 2_556 ? 104 AE2 5 ASN B 495 ? ASN B 468 . ? 1_555 ? 105 AE2 5 GLN B 503 ? GLN B 476 . ? 1_555 ? 106 AE2 5 HOH Y . ? HOH B 739 . ? 2_556 ? 107 AE2 5 HOH Y . ? HOH B 811 . ? 1_555 ? 108 AE3 7 LEU B 465 ? LEU B 438 . ? 2_556 ? 109 AE3 7 PRO B 466 ? PRO B 439 . ? 2_556 ? 110 AE3 7 VAL B 513 ? VAL B 486 . ? 1_555 ? 111 AE3 7 ASN B 515 ? ASN B 488 . ? 1_555 ? 112 AE3 7 ASN B 539 ? ASN B 512 . ? 1_555 ? 113 AE3 7 TYR B 541 ? TYR B 514 . ? 1_555 ? 114 AE3 7 HOH Y . ? HOH B 804 . ? 1_555 ? # _atom_sites.entry_id 5FBK _atom_sites.fract_transf_matrix[1][1] 0.005852 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.001579 _atom_sites.fract_transf_matrix[2][1] -0.000000 _atom_sites.fract_transf_matrix[2][2] 0.012060 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] -0.000000 _atom_sites.fract_transf_matrix[3][3] 0.010989 _atom_sites.fract_transf_vector[1] 0.000000 _atom_sites.fract_transf_vector[2] 0.000000 _atom_sites.fract_transf_vector[3] 0.000000 # loop_ _atom_type.symbol C CL MG N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . PRO A 1 49 ? -9.676 -3.448 19.256 1.00 82.29 ? 22 PRO A N 1 ATOM 2 C CA . PRO A 1 49 ? -9.670 -4.085 17.950 1.00 79.86 ? 22 PRO A CA 1 ATOM 3 C C . PRO A 1 49 ? -8.590 -5.171 17.802 1.00 84.09 ? 22 PRO A C 1 ATOM 4 O O . PRO A 1 49 ? -8.462 -5.738 16.715 1.00 78.38 ? 22 PRO A O 1 ATOM 5 C CB . PRO A 1 49 ? -9.384 -2.916 16.998 1.00 78.74 ? 22 PRO A CB 1 ATOM 6 N N . ASP A 1 50 ? -7.846 -5.465 18.879 1.00 82.00 ? 23 ASP A N 1 ATOM 7 C CA . ASP A 1 50 ? -6.716 -6.419 18.849 1.00 80.51 ? 23 ASP A CA 1 ATOM 8 C C . ASP A 1 50 ? -7.157 -7.875 18.644 1.00 76.12 ? 23 ASP A C 1 ATOM 9 O O . ASP A 1 50 ? -6.915 -8.462 17.587 1.00 80.73 ? 23 ASP A O 1 ATOM 10 C CB . ASP A 1 50 ? -5.869 -6.305 20.135 1.00 74.67 ? 23 ASP A CB 1 ATOM 11 N N . GLN A 1 51 ? -7.794 -8.463 19.653 1.00 77.23 ? 24 GLN A N 1 ATOM 12 C CA . GLN A 1 51 ? -8.326 -9.823 19.512 1.00 70.02 ? 24 GLN A CA 1 ATOM 13 C C . GLN A 1 51 ? -9.689 -9.795 18.785 1.00 62.84 ? 24 GLN A C 1 ATOM 14 O O . GLN A 1 51 ? -10.557 -8.962 19.029 1.00 54.55 ? 24 GLN A O 1 ATOM 15 C CB . GLN A 1 51 ? -8.362 -10.562 20.844 1.00 71.02 ? 24 GLN A CB 1 ATOM 16 C CG . GLN A 1 51 ? -9.242 -9.949 21.904 1.00 72.11 ? 24 GLN A CG 1 ATOM 17 C CD . GLN A 1 51 ? -9.314 -10.829 23.128 1.00 75.80 ? 24 GLN A CD 1 ATOM 18 O OE1 . GLN A 1 51 ? -10.391 -11.066 23.671 1.00 78.66 ? 24 GLN A OE1 1 ATOM 19 N NE2 . GLN A 1 51 ? -8.166 -11.334 23.566 1.00 75.63 ? 24 GLN A NE2 1 ATOM 20 N N . ARG A 1 52 ? -9.814 -10.680 17.820 1.00 56.51 ? 25 ARG A N 1 ATOM 21 C CA . ARG A 1 52 ? -10.893 -10.631 16.870 1.00 53.41 ? 25 ARG A CA 1 ATOM 22 C C . ARG A 1 52 ? -10.904 -11.938 16.134 1.00 47.40 ? 25 ARG A C 1 ATOM 23 O O . ARG A 1 52 ? -9.954 -12.700 16.221 1.00 45.87 ? 25 ARG A O 1 ATOM 24 C CB . ARG A 1 52 ? -10.679 -9.479 15.877 1.00 56.32 ? 25 ARG A CB 1 ATOM 25 C CG . ARG A 1 52 ? -9.394 -9.587 15.068 1.00 61.19 ? 25 ARG A CG 1 ATOM 26 C CD . ARG A 1 52 ? -9.351 -8.594 13.913 1.00 61.99 ? 25 ARG A CD 1 ATOM 27 N NE . ARG A 1 52 ? -9.099 -7.226 14.366 1.00 61.66 ? 25 ARG A NE 1 ATOM 28 C CZ . ARG A 1 52 ? -9.220 -6.140 13.606 1.00 63.99 ? 25 ARG A CZ 1 ATOM 29 N NH1 . ARG A 1 52 ? -9.594 -6.238 12.332 1.00 65.41 ? 25 ARG A NH1 1 ATOM 30 N NH2 . ARG A 1 52 ? -8.971 -4.944 14.126 1.00 65.55 ? 25 ARG A NH2 1 ATOM 31 N N . ALA A 1 53 ? -11.976 -12.196 15.407 1.00 46.15 ? 26 ALA A N 1 ATOM 32 C CA . ALA A 1 53 ? -12.005 -13.271 14.439 1.00 44.71 ? 26 ALA A CA 1 ATOM 33 C C . ALA A 1 53 ? -12.249 -12.615 13.114 1.00 45.57 ? 26 ALA A C 1 ATOM 34 O O . ALA A 1 53 ? -13.202 -11.860 12.952 1.00 43.64 ? 26 ALA A O 1 ATOM 35 C CB . ALA A 1 53 ? -13.093 -14.270 14.749 1.00 48.01 ? 26 ALA A CB 1 ATOM 36 N N . GLN A 1 54 ? -11.365 -12.895 12.163 1.00 49.44 ? 27 GLN A N 1 ATOM 37 C CA . GLN A 1 54 ? -11.311 -12.164 10.905 1.00 52.82 ? 27 GLN A CA 1 ATOM 38 C C . GLN A 1 54 ? -10.893 -13.063 9.754 1.00 54.40 ? 27 GLN A C 1 ATOM 39 O O . GLN A 1 54 ? -10.006 -13.905 9.908 1.00 50.74 ? 27 GLN A O 1 ATOM 40 C CB . GLN A 1 54 ? -10.335 -10.999 11.024 1.00 56.70 ? 27 GLN A CB 1 ATOM 41 C CG . GLN A 1 54 ? -9.997 -10.347 9.694 1.00 64.76 ? 27 GLN A CG 1 ATOM 42 C CD . GLN A 1 54 ? -9.872 -8.846 9.786 1.00 70.87 ? 27 GLN A CD 1 ATOM 43 O OE1 . GLN A 1 54 ? -9.838 -8.274 10.876 1.00 69.72 ? 27 GLN A OE1 1 ATOM 44 N NE2 . GLN A 1 54 ? -9.835 -8.188 8.628 1.00 78.74 ? 27 GLN A NE2 1 ATOM 45 N N . LYS A 1 55 ? -11.561 -12.887 8.617 1.00 54.92 ? 28 LYS A N 1 ATOM 46 C CA . LYS A 1 55 ? -11.209 -13.572 7.397 1.00 56.50 ? 28 LYS A CA 1 ATOM 47 C C . LYS A 1 55 ? -11.694 -12.788 6.186 1.00 55.88 ? 28 LYS A C 1 ATOM 48 O O . LYS A 1 55 ? -12.852 -12.351 6.128 1.00 52.48 ? 28 LYS A O 1 ATOM 49 C CB . LYS A 1 55 ? -11.804 -14.969 7.376 1.00 62.41 ? 28 LYS A CB 1 ATOM 50 C CG . LYS A 1 55 ? -11.331 -15.781 6.187 1.00 68.07 ? 28 LYS A CG 1 ATOM 51 C CD . LYS A 1 55 ? -11.744 -17.232 6.310 1.00 70.95 ? 28 LYS A CD 1 ATOM 52 C CE . LYS A 1 55 ? -11.295 -18.018 5.092 1.00 74.32 ? 28 LYS A CE 1 ATOM 53 N NZ . LYS A 1 55 ? -11.678 -19.445 5.236 1.00 81.80 ? 28 LYS A NZ 1 ATOM 54 N N . LYS A 1 56 ? -10.804 -12.636 5.207 1.00 49.91 ? 29 LYS A N 1 ATOM 55 C CA . LYS A 1 56 ? -11.094 -11.864 4.007 1.00 47.29 ? 29 LYS A CA 1 ATOM 56 C C . LYS A 1 56 ? -12.137 -12.572 3.136 1.00 43.76 ? 29 LYS A C 1 ATOM 57 O O . LYS A 1 56 ? -12.335 -13.776 3.239 1.00 43.99 ? 29 LYS A O 1 ATOM 58 C CB . LYS A 1 56 ? -9.800 -11.605 3.216 1.00 45.06 ? 29 LYS A CB 1 ATOM 59 N N . GLY A 1 57 ? -12.809 -11.790 2.298 1.00 43.74 ? 30 GLY A N 1 ATOM 60 C CA . GLY A 1 57 ? -13.831 -12.282 1.372 1.00 43.07 ? 30 GLY A CA 1 ATOM 61 C C . GLY A 1 57 ? -14.239 -11.148 0.448 1.00 44.68 ? 30 GLY A C 1 ATOM 62 O O . GLY A 1 57 ? -13.727 -10.039 0.550 1.00 46.96 ? 30 GLY A O 1 ATOM 63 N N . ASP A 1 58 ? -15.162 -11.412 -0.462 1.00 48.36 ? 31 ASP A N 1 ATOM 64 C CA . ASP A 1 58 ? -15.648 -10.373 -1.362 1.00 51.96 ? 31 ASP A CA 1 ATOM 65 C C . ASP A 1 58 ? -16.646 -9.470 -0.656 1.00 53.78 ? 31 ASP A C 1 ATOM 66 O O . ASP A 1 58 ? -16.737 -8.278 -0.953 1.00 52.65 ? 31 ASP A O 1 ATOM 67 C CB . ASP A 1 58 ? -16.309 -11.016 -2.577 1.00 58.18 ? 31 ASP A CB 1 ATOM 68 C CG . ASP A 1 58 ? -15.353 -11.920 -3.343 1.00 61.60 ? 31 ASP A CG 1 ATOM 69 O OD1 . ASP A 1 58 ? -14.240 -11.447 -3.684 1.00 60.70 ? 31 ASP A OD1 1 ATOM 70 O OD2 . ASP A 1 58 ? -15.711 -13.097 -3.568 1.00 62.89 ? 31 ASP A OD2 1 ATOM 71 N N . ILE A 1 59 ? -17.430 -10.068 0.239 1.00 53.40 ? 32 ILE A N 1 ATOM 72 C CA . ILE A 1 59 ? -18.450 -9.356 0.997 1.00 55.54 ? 32 ILE A CA 1 ATOM 73 C C . ILE A 1 59 ? -18.235 -9.692 2.462 1.00 52.70 ? 32 ILE A C 1 ATOM 74 O O . ILE A 1 59 ? -18.221 -10.859 2.832 1.00 52.87 ? 32 ILE A O 1 ATOM 75 C CB . ILE A 1 59 ? -19.872 -9.748 0.539 1.00 56.76 ? 32 ILE A CB 1 ATOM 76 C CG1 . ILE A 1 59 ? -20.156 -9.215 -0.871 1.00 60.61 ? 32 ILE A CG1 1 ATOM 77 C CG2 . ILE A 1 59 ? -20.923 -9.174 1.469 1.00 57.45 ? 32 ILE A CG2 1 ATOM 78 C CD1 . ILE A 1 59 ? -21.230 -10.002 -1.597 1.00 63.02 ? 32 ILE A CD1 1 ATOM 79 N N . ILE A 1 60 ? -18.060 -8.658 3.279 1.00 50.51 ? 33 ILE A N 1 ATOM 80 C CA . ILE A 1 60 ? -17.705 -8.813 4.694 1.00 50.66 ? 33 ILE A CA 1 ATOM 81 C C . ILE A 1 60 ? -18.911 -8.606 5.617 1.00 48.10 ? 33 ILE A C 1 ATOM 82 O O . ILE A 1 60 ? -19.586 -7.588 5.520 1.00 47.33 ? 33 ILE A O 1 ATOM 83 C CB . ILE A 1 60 ? -16.626 -7.784 5.106 1.00 53.68 ? 33 ILE A CB 1 ATOM 84 C CG1 . ILE A 1 60 ? -15.444 -7.798 4.122 1.00 55.01 ? 33 ILE A CG1 1 ATOM 85 C CG2 . ILE A 1 60 ? -16.144 -8.041 6.537 1.00 53.32 ? 33 ILE A CG2 1 ATOM 86 C CD1 . ILE A 1 60 ? -14.734 -9.133 4.014 1.00 57.50 ? 33 ILE A CD1 1 ATOM 87 N N . LEU A 1 61 ? -19.169 -9.578 6.494 1.00 44.91 ? 34 LEU A N 1 ATOM 88 C CA . LEU A 1 61 ? -20.132 -9.433 7.584 1.00 42.28 ? 34 LEU A CA 1 ATOM 89 C C . LEU A 1 61 ? -19.413 -9.085 8.884 1.00 41.02 ? 34 LEU A C 1 ATOM 90 O O . LEU A 1 61 ? -18.482 -9.774 9.302 1.00 42.05 ? 34 LEU A O 1 ATOM 91 C CB . LEU A 1 61 ? -20.934 -10.723 7.807 1.00 42.54 ? 34 LEU A CB 1 ATOM 92 C CG . LEU A 1 61 ? -21.682 -11.368 6.644 1.00 45.54 ? 34 LEU A CG 1 ATOM 93 C CD1 . LEU A 1 61 ? -22.790 -12.266 7.155 1.00 47.16 ? 34 LEU A CD1 1 ATOM 94 C CD2 . LEU A 1 61 ? -22.259 -10.362 5.672 1.00 51.52 ? 34 LEU A CD2 1 ATOM 95 N N . GLY A 1 62 ? -19.853 -8.010 9.524 1.00 40.18 ? 35 GLY A N 1 ATOM 96 C CA . GLY A 1 62 ? -19.422 -7.703 10.889 1.00 36.37 ? 35 GLY A CA 1 ATOM 97 C C . GLY A 1 62 ? -20.122 -8.618 11.872 1.00 33.37 ? 35 GLY A C 1 ATOM 98 O O . GLY A 1 62 ? -21.230 -9.110 11.594 1.00 34.95 ? 35 GLY A O 1 ATOM 99 N N . GLY A 1 63 ? -19.483 -8.857 13.008 1.00 30.93 ? 36 GLY A N 1 ATOM 100 C CA . GLY A 1 63 ? -20.068 -9.644 14.093 1.00 31.86 ? 36 GLY A CA 1 ATOM 101 C C . GLY A 1 63 ? -19.750 -9.031 15.453 1.00 33.11 ? 36 GLY A C 1 ATOM 102 O O . GLY A 1 63 ? -18.669 -8.492 15.652 1.00 31.59 ? 36 GLY A O 1 ATOM 103 N N . LEU A 1 64 ? -20.704 -9.110 16.381 1.00 34.39 ? 37 LEU A N 1 ATOM 104 C CA . LEU A 1 64 ? -20.507 -8.641 17.749 1.00 32.53 ? 37 LEU A CA 1 ATOM 105 C C . LEU A 1 64 ? -21.057 -9.692 18.702 1.00 30.49 ? 37 LEU A C 1 ATOM 106 O O . LEU A 1 64 ? -22.232 -10.074 18.594 1.00 31.90 ? 37 LEU A O 1 ATOM 107 C CB . LEU A 1 64 ? -21.250 -7.323 17.952 1.00 35.08 ? 37 LEU A CB 1 ATOM 108 C CG . LEU A 1 64 ? -20.772 -5.879 17.695 1.00 34.64 ? 37 LEU A CG 1 ATOM 109 C CD1 . LEU A 1 64 ? -19.386 -5.755 17.115 1.00 36.22 ? 37 LEU A CD1 1 ATOM 110 C CD2 . LEU A 1 64 ? -21.790 -5.023 16.949 1.00 34.47 ? 37 LEU A CD2 1 ATOM 111 N N . PHE A 1 65 ? -20.221 -10.150 19.627 1.00 28.61 ? 38 PHE A N 1 ATOM 112 C CA . PHE A 1 65 ? -20.595 -11.183 20.576 1.00 29.67 ? 38 PHE A CA 1 ATOM 113 C C . PHE A 1 65 ? -19.965 -10.897 21.933 1.00 29.05 ? 38 PHE A C 1 ATOM 114 O O . PHE A 1 65 ? -18.876 -10.340 22.016 1.00 30.93 ? 38 PHE A O 1 ATOM 115 C CB . PHE A 1 65 ? -20.145 -12.581 20.097 1.00 31.87 ? 38 PHE A CB 1 ATOM 116 C CG . PHE A 1 65 ? -20.760 -12.988 18.781 1.00 31.46 ? 38 PHE A CG 1 ATOM 117 C CD1 . PHE A 1 65 ? -20.171 -12.624 17.587 1.00 31.80 ? 38 PHE A CD1 1 ATOM 118 C CD2 . PHE A 1 65 ? -21.923 -13.716 18.750 1.00 31.26 ? 38 PHE A CD2 1 ATOM 119 C CE1 . PHE A 1 65 ? -20.744 -12.959 16.380 1.00 31.98 ? 38 PHE A CE1 1 ATOM 120 C CE2 . PHE A 1 65 ? -22.500 -14.074 17.550 1.00 33.65 ? 38 PHE A CE2 1 ATOM 121 C CZ . PHE A 1 65 ? -21.905 -13.687 16.359 1.00 34.02 ? 38 PHE A CZ 1 ATOM 122 N N . PRO A 1 66 ? -20.645 -11.293 23.006 1.00 29.03 ? 39 PRO A N 1 ATOM 123 C CA . PRO A 1 66 ? -20.092 -11.166 24.344 1.00 32.62 ? 39 PRO A CA 1 ATOM 124 C C . PRO A 1 66 ? -19.203 -12.382 24.715 1.00 33.55 ? 39 PRO A C 1 ATOM 125 O O . PRO A 1 66 ? -19.647 -13.318 25.382 1.00 34.36 ? 39 PRO A O 1 ATOM 126 C CB . PRO A 1 66 ? -21.343 -11.100 25.207 1.00 31.34 ? 39 PRO A CB 1 ATOM 127 C CG . PRO A 1 66 ? -22.318 -11.977 24.476 1.00 30.53 ? 39 PRO A CG 1 ATOM 128 C CD . PRO A 1 66 ? -21.950 -11.964 23.022 1.00 29.30 ? 39 PRO A CD 1 ATOM 129 N N . ILE A 1 67 ? -17.947 -12.329 24.288 1.00 35.15 ? 40 ILE A N 1 ATOM 130 C CA . ILE A 1 67 ? -16.952 -13.366 24.608 1.00 35.71 ? 40 ILE A CA 1 ATOM 131 C C . ILE A 1 67 ? -16.520 -13.276 26.080 1.00 34.97 ? 40 ILE A C 1 ATOM 132 O O . ILE A 1 67 ? -16.189 -14.282 26.699 1.00 32.87 ? 40 ILE A O 1 ATOM 133 C CB . ILE A 1 67 ? -15.733 -13.244 23.671 1.00 35.41 ? 40 ILE A CB 1 ATOM 134 C CG1 . ILE A 1 67 ? -16.199 -13.259 22.211 1.00 35.59 ? 40 ILE A CG1 1 ATOM 135 C CG2 . ILE A 1 67 ? -14.730 -14.362 23.942 1.00 37.67 ? 40 ILE A CG2 1 ATOM 136 C CD1 . ILE A 1 67 ? -17.086 -14.427 21.837 1.00 37.33 ? 40 ILE A CD1 1 ATOM 137 N N . HIS A 1 68 ? -16.568 -12.070 26.642 1.00 36.69 ? 41 HIS A N 1 ATOM 138 C CA . HIS A 1 68 ? -16.546 -11.921 28.083 1.00 37.80 ? 41 HIS A CA 1 ATOM 139 C C . HIS A 1 68 ? -17.843 -11.352 28.616 1.00 35.08 ? 41 HIS A C 1 ATOM 140 O O . HIS A 1 68 ? -18.559 -10.628 27.919 1.00 35.14 ? 41 HIS A O 1 ATOM 141 C CB . HIS A 1 68 ? -15.421 -11.014 28.497 1.00 38.46 ? 41 HIS A CB 1 ATOM 142 C CG . HIS A 1 68 ? -14.084 -11.547 28.131 1.00 41.05 ? 41 HIS A CG 1 ATOM 143 N ND1 . HIS A 1 68 ? -13.555 -11.398 26.869 1.00 40.74 ? 41 HIS A ND1 1 ATOM 144 C CD2 . HIS A 1 68 ? -13.181 -12.261 28.845 1.00 39.19 ? 41 HIS A CD2 1 ATOM 145 C CE1 . HIS A 1 68 ? -12.363 -11.972 26.829 1.00 41.37 ? 41 HIS A CE1 1 ATOM 146 N NE2 . HIS A 1 68 ? -12.124 -12.519 28.007 1.00 41.47 ? 41 HIS A NE2 1 ATOM 147 N N . PHE A 1 69 ? -18.125 -11.677 29.874 1.00 33.69 ? 42 PHE A N 1 ATOM 148 C CA . PHE A 1 69 ? -19.377 -11.269 30.514 1.00 35.81 ? 42 PHE A CA 1 ATOM 149 C C . PHE A 1 69 ? -19.397 -9.806 30.916 1.00 34.91 ? 42 PHE A C 1 ATOM 150 O O . PHE A 1 69 ? -20.456 -9.239 31.136 1.00 36.36 ? 42 PHE A O 1 ATOM 151 C CB . PHE A 1 69 ? -19.675 -12.131 31.752 1.00 36.28 ? 42 PHE A CB 1 ATOM 152 C CG . PHE A 1 69 ? -20.250 -13.482 31.433 1.00 36.94 ? 42 PHE A CG 1 ATOM 153 C CD1 . PHE A 1 69 ? -21.469 -13.589 30.800 1.00 38.63 ? 42 PHE A CD1 1 ATOM 154 C CD2 . PHE A 1 69 ? -19.610 -14.640 31.836 1.00 40.81 ? 42 PHE A CD2 1 ATOM 155 C CE1 . PHE A 1 69 ? -22.020 -14.832 30.531 1.00 39.70 ? 42 PHE A CE1 1 ATOM 156 C CE2 . PHE A 1 69 ? -20.158 -15.887 31.579 1.00 40.55 ? 42 PHE A CE2 1 ATOM 157 C CZ . PHE A 1 69 ? -21.363 -15.983 30.920 1.00 40.96 ? 42 PHE A CZ 1 ATOM 158 N N . GLY A 1 70 ? -18.231 -9.203 31.038 1.00 34.16 ? 43 GLY A N 1 ATOM 159 C CA . GLY A 1 70 ? -18.162 -7.888 31.574 1.00 36.07 ? 43 GLY A CA 1 ATOM 160 C C . GLY A 1 70 ? -16.755 -7.359 31.515 1.00 40.84 ? 43 GLY A C 1 ATOM 161 O O . GLY A 1 70 ? -15.881 -7.907 30.829 1.00 40.28 ? 43 GLY A O 1 ATOM 162 N N . VAL A 1 71 ? -16.572 -6.272 32.237 1.00 40.40 ? 44 VAL A N 1 ATOM 163 C CA . VAL A 1 71 ? -15.357 -5.516 32.235 1.00 44.90 ? 44 VAL A CA 1 ATOM 164 C C . VAL A 1 71 ? -14.930 -5.326 33.720 1.00 48.60 ? 44 VAL A C 1 ATOM 165 O O . VAL A 1 71 ? -15.756 -5.374 34.654 1.00 42.38 ? 44 VAL A O 1 ATOM 166 C CB . VAL A 1 71 ? -15.627 -4.177 31.512 1.00 48.52 ? 44 VAL A CB 1 ATOM 167 C CG1 . VAL A 1 71 ? -14.872 -3.053 32.145 1.00 54.16 ? 44 VAL A CG1 1 ATOM 168 C CG2 . VAL A 1 71 ? -15.309 -4.270 30.020 1.00 45.91 ? 44 VAL A CG2 1 ATOM 169 N N . ALA A 1 72 ? -13.637 -5.131 33.922 1.00 50.64 ? 45 ALA A N 1 ATOM 170 C CA . ALA A 1 72 ? -13.072 -4.901 35.244 1.00 56.60 ? 45 ALA A CA 1 ATOM 171 C C . ALA A 1 72 ? -13.425 -3.480 35.673 1.00 61.72 ? 45 ALA A C 1 ATOM 172 O O . ALA A 1 72 ? -12.938 -2.506 35.106 1.00 67.02 ? 45 ALA A O 1 ATOM 173 C CB . ALA A 1 72 ? -11.562 -5.114 35.202 1.00 58.12 ? 45 ALA A CB 1 ATOM 174 N N . ALA A 1 73 ? -14.324 -3.371 36.640 1.00 73.91 ? 46 ALA A N 1 ATOM 175 C CA . ALA A 1 73 ? -14.789 -2.067 37.105 1.00 85.27 ? 46 ALA A CA 1 ATOM 176 C C . ALA A 1 73 ? -13.646 -1.395 37.834 1.00 86.97 ? 46 ALA A C 1 ATOM 177 O O . ALA A 1 73 ? -13.168 -1.918 38.830 1.00 90.62 ? 46 ALA A O 1 ATOM 178 C CB . ALA A 1 73 ? -15.978 -2.224 38.040 1.00 89.09 ? 46 ALA A CB 1 ATOM 179 N N . LYS A 1 74 ? -13.198 -0.253 37.329 1.00 85.00 ? 47 LYS A N 1 ATOM 180 C CA . LYS A 1 74 ? -12.045 0.426 37.903 1.00 80.17 ? 47 LYS A CA 1 ATOM 181 C C . LYS A 1 74 ? -12.193 1.923 37.696 1.00 80.75 ? 47 LYS A C 1 ATOM 182 O O . LYS A 1 74 ? -11.777 2.438 36.654 1.00 92.14 ? 47 LYS A O 1 ATOM 183 C CB . LYS A 1 74 ? -10.769 -0.080 37.233 1.00 77.97 ? 47 LYS A CB 1 ATOM 184 N N . ASP A 1 75 ? -12.780 2.622 38.674 1.00 77.92 ? 48 ASP A N 1 ATOM 185 C CA . ASP A 1 75 ? -13.039 4.067 38.544 1.00 74.08 ? 48 ASP A CA 1 ATOM 186 C C . ASP A 1 75 ? -11.730 4.777 38.200 1.00 69.74 ? 48 ASP A C 1 ATOM 187 O O . ASP A 1 75 ? -10.708 4.565 38.865 1.00 64.90 ? 48 ASP A O 1 ATOM 188 C CB . ASP A 1 75 ? -13.649 4.655 39.828 1.00 76.07 ? 48 ASP A CB 1 ATOM 189 N N . GLN A 1 76 ? -11.749 5.560 37.122 1.00 62.45 ? 49 GLN A N 1 ATOM 190 C CA . GLN A 1 76 ? -10.559 6.272 36.679 1.00 64.64 ? 49 GLN A CA 1 ATOM 191 C C . GLN A 1 76 ? -10.508 7.617 37.390 1.00 54.94 ? 49 GLN A C 1 ATOM 192 O O . GLN A 1 76 ? -11.451 8.408 37.328 1.00 52.18 ? 49 GLN A O 1 ATOM 193 C CB . GLN A 1 76 ? -10.566 6.483 35.161 1.00 71.66 ? 49 GLN A CB 1 ATOM 194 C CG . GLN A 1 76 ? -9.225 6.238 34.481 1.00 77.22 ? 49 GLN A CG 1 ATOM 195 C CD . GLN A 1 76 ? -9.170 4.922 33.722 1.00 80.91 ? 49 GLN A CD 1 ATOM 196 O OE1 . GLN A 1 76 ? -10.202 4.363 33.344 1.00 87.10 ? 49 GLN A OE1 1 ATOM 197 N NE2 . GLN A 1 76 ? -7.957 4.423 33.487 1.00 82.95 ? 49 GLN A NE2 1 ATOM 198 N N . ASP A 1 77 ? -9.413 7.871 38.089 1.00 47.49 ? 50 ASP A N 1 ATOM 199 C CA . ASP A 1 77 ? -9.258 9.145 38.769 1.00 46.42 ? 50 ASP A CA 1 ATOM 200 C C . ASP A 1 77 ? -8.742 10.240 37.818 1.00 39.50 ? 50 ASP A C 1 ATOM 201 O O . ASP A 1 77 ? -8.710 11.411 38.192 1.00 39.29 ? 50 ASP A O 1 ATOM 202 C CB . ASP A 1 77 ? -8.378 8.994 40.030 1.00 50.64 ? 50 ASP A CB 1 ATOM 203 C CG . ASP A 1 77 ? -7.015 8.384 39.741 1.00 55.50 ? 50 ASP A CG 1 ATOM 204 O OD1 . ASP A 1 77 ? -6.583 8.385 38.560 1.00 54.40 ? 50 ASP A OD1 1 ATOM 205 O OD2 . ASP A 1 77 ? -6.379 7.896 40.707 1.00 63.25 ? 50 ASP A OD2 1 ATOM 206 N N . LEU A 1 78 ? -8.340 9.845 36.608 1.00 36.67 ? 51 LEU A N 1 ATOM 207 C CA . LEU A 1 78 ? -7.846 10.749 35.576 1.00 38.09 ? 51 LEU A CA 1 ATOM 208 C C . LEU A 1 78 ? -6.656 11.609 36.021 1.00 40.61 ? 51 LEU A C 1 ATOM 209 O O . LEU A 1 78 ? -6.553 12.792 35.653 1.00 40.26 ? 51 LEU A O 1 ATOM 210 C CB . LEU A 1 78 ? -8.969 11.644 35.069 1.00 36.38 ? 51 LEU A CB 1 ATOM 211 C CG . LEU A 1 78 ? -10.207 10.932 34.561 1.00 40.18 ? 51 LEU A CG 1 ATOM 212 C CD1 . LEU A 1 78 ? -11.267 11.965 34.212 1.00 43.03 ? 51 LEU A CD1 1 ATOM 213 C CD2 . LEU A 1 78 ? -9.860 10.097 33.350 1.00 40.92 ? 51 LEU A CD2 1 ATOM 214 N N . LYS A 1 79 ? -5.777 11.017 36.828 1.00 40.81 ? 52 LYS A N 1 ATOM 215 C CA . LYS A 1 79 ? -4.483 11.599 37.162 1.00 42.35 ? 52 LYS A CA 1 ATOM 216 C C . LYS A 1 79 ? -3.488 11.376 36.032 1.00 40.50 ? 52 LYS A C 1 ATOM 217 O O . LYS A 1 79 ? -2.534 12.120 35.897 1.00 45.70 ? 52 LYS A O 1 ATOM 218 C CB . LYS A 1 79 ? -3.949 11.006 38.473 1.00 46.67 ? 52 LYS A CB 1 ATOM 219 C CG . LYS A 1 79 ? -4.616 11.644 39.682 1.00 53.69 ? 52 LYS A CG 1 ATOM 220 C CD . LYS A 1 79 ? -4.554 10.789 40.932 1.00 58.99 ? 52 LYS A CD 1 ATOM 221 C CE . LYS A 1 79 ? -4.194 11.595 42.157 1.00 64.58 ? 52 LYS A CE 1 ATOM 222 N NZ . LYS A 1 79 ? -2.730 11.489 42.392 1.00 69.92 ? 52 LYS A NZ 1 ATOM 223 N N . SER A 1 80 ? -3.714 10.348 35.233 1.00 41.18 ? 53 SER A N 1 ATOM 224 C CA . SER A 1 80 ? -2.952 10.110 34.014 1.00 45.55 ? 53 SER A CA 1 ATOM 225 C C . SER A 1 80 ? -3.937 9.684 32.928 1.00 45.13 ? 53 SER A C 1 ATOM 226 O O . SER A 1 80 ? -5.123 9.481 33.205 1.00 43.66 ? 53 SER A O 1 ATOM 227 C CB . SER A 1 80 ? -1.923 9.013 34.246 1.00 44.27 ? 53 SER A CB 1 ATOM 228 O OG . SER A 1 80 ? -2.543 7.889 34.830 1.00 48.98 ? 53 SER A OG 1 ATOM 229 N N . ARG A 1 81 ? -3.455 9.565 31.697 1.00 47.33 ? 54 ARG A N 1 ATOM 230 C CA . ARG A 1 81 ? -4.335 9.330 30.553 1.00 50.10 ? 54 ARG A CA 1 ATOM 231 C C . ARG A 1 81 ? -5.108 8.039 30.738 1.00 49.07 ? 54 ARG A C 1 ATOM 232 O O . ARG A 1 81 ? -4.521 7.021 31.067 1.00 45.12 ? 54 ARG A O 1 ATOM 233 C CB . ARG A 1 81 ? -3.543 9.255 29.256 1.00 55.73 ? 54 ARG A CB 1 ATOM 234 C CG . ARG A 1 81 ? -4.429 8.988 28.044 1.00 66.54 ? 54 ARG A CG 1 ATOM 235 C CD . ARG A 1 81 ? -3.717 8.970 26.710 1.00 70.13 ? 54 ARG A CD 1 ATOM 236 N NE . ARG A 1 81 ? -3.036 10.225 26.421 1.00 76.96 ? 54 ARG A NE 1 ATOM 237 C CZ . ARG A 1 81 ? -1.769 10.492 26.729 1.00 79.08 ? 54 ARG A CZ 1 ATOM 238 N NH1 . ARG A 1 81 ? -1.007 9.591 27.348 1.00 79.46 ? 54 ARG A NH1 1 ATOM 239 N NH2 . ARG A 1 81 ? -1.258 11.676 26.417 1.00 78.68 ? 54 ARG A NH2 1 ATOM 240 N N . PRO A 1 82 ? -6.427 8.065 30.502 1.00 48.76 ? 55 PRO A N 1 ATOM 241 C CA . PRO A 1 82 ? -7.150 6.814 30.732 1.00 50.03 ? 55 PRO A CA 1 ATOM 242 C C . PRO A 1 82 ? -6.672 5.697 29.815 1.00 46.63 ? 55 PRO A C 1 ATOM 243 O O . PRO A 1 82 ? -6.417 5.926 28.651 1.00 53.40 ? 55 PRO A O 1 ATOM 244 C CB . PRO A 1 82 ? -8.608 7.182 30.406 1.00 50.83 ? 55 PRO A CB 1 ATOM 245 C CG . PRO A 1 82 ? -8.649 8.673 30.437 1.00 49.93 ? 55 PRO A CG 1 ATOM 246 C CD . PRO A 1 82 ? -7.306 9.106 29.946 1.00 47.66 ? 55 PRO A CD 1 ATOM 247 N N . GLU A 1 83 ? -6.536 4.505 30.365 1.00 48.32 ? 56 GLU A N 1 ATOM 248 C CA . GLU A 1 83 ? -6.211 3.304 29.603 1.00 54.67 ? 56 GLU A CA 1 ATOM 249 C C . GLU A 1 83 ? -7.503 2.553 29.276 1.00 53.52 ? 56 GLU A C 1 ATOM 250 O O . GLU A 1 83 ? -8.536 2.824 29.865 1.00 54.99 ? 56 GLU A O 1 ATOM 251 C CB . GLU A 1 83 ? -5.293 2.393 30.437 1.00 57.12 ? 56 GLU A CB 1 ATOM 252 N N . SER A 1 84 ? -7.441 1.601 28.358 1.00 50.75 ? 57 SER A N 1 ATOM 253 C CA . SER A 1 84 ? -8.621 0.823 27.994 1.00 51.09 ? 57 SER A CA 1 ATOM 254 C C . SER A 1 84 ? -9.020 -0.129 29.144 1.00 51.48 ? 57 SER A C 1 ATOM 255 O O . SER A 1 84 ? -8.181 -0.561 29.933 1.00 49.33 ? 57 SER A O 1 ATOM 256 C CB . SER A 1 84 ? -8.343 0.037 26.718 1.00 54.25 ? 57 SER A CB 1 ATOM 257 O OG . SER A 1 84 ? -7.460 -1.032 27.021 1.00 63.03 ? 57 SER A OG 1 ATOM 258 N N . VAL A 1 85 ? -10.303 -0.458 29.225 1.00 53.00 ? 58 VAL A N 1 ATOM 259 C CA . VAL A 1 85 ? -10.791 -1.339 30.284 1.00 51.64 ? 58 VAL A CA 1 ATOM 260 C C . VAL A 1 85 ? -10.498 -2.806 29.935 1.00 49.88 ? 58 VAL A C 1 ATOM 261 O O . VAL A 1 85 ? -10.384 -3.177 28.765 1.00 46.07 ? 58 VAL A O 1 ATOM 262 C CB . VAL A 1 85 ? -12.315 -1.201 30.603 1.00 56.30 ? 58 VAL A CB 1 ATOM 263 C CG1 . VAL A 1 85 ? -12.531 -1.267 32.118 1.00 56.05 ? 58 VAL A CG1 1 ATOM 264 C CG2 . VAL A 1 85 ? -12.937 0.084 30.049 1.00 56.62 ? 58 VAL A CG2 1 ATOM 265 N N . GLU A 1 86 ? -10.366 -3.613 30.982 1.00 49.10 ? 59 GLU A N 1 ATOM 266 C CA . GLU A 1 86 ? -10.018 -5.020 30.897 1.00 48.13 ? 59 GLU A CA 1 ATOM 267 C C . GLU A 1 86 ? -11.296 -5.791 30.867 1.00 45.70 ? 59 GLU A C 1 ATOM 268 O O . GLU A 1 86 ? -12.126 -5.601 31.752 1.00 45.03 ? 59 GLU A O 1 ATOM 269 C CB . GLU A 1 86 ? -9.276 -5.441 32.192 1.00 52.13 ? 59 GLU A CB 1 ATOM 270 C CG . GLU A 1 86 ? -8.277 -6.593 32.068 1.00 53.46 ? 59 GLU A CG 1 ATOM 271 C CD . GLU A 1 86 ? -7.936 -7.275 33.417 1.00 58.63 ? 59 GLU A CD 1 ATOM 272 O OE1 . GLU A 1 86 ? -8.199 -6.692 34.508 1.00 52.62 ? 59 GLU A OE1 1 ATOM 273 O OE2 . GLU A 1 86 ? -7.414 -8.431 33.391 1.00 55.41 ? 59 GLU A OE2 1 ATOM 274 N N . CYS A 1 87 ? -11.447 -6.678 29.888 1.00 48.01 ? 60 CYS A N 1 ATOM 275 C CA . CYS A 1 87 ? -12.572 -7.585 29.861 1.00 47.24 ? 60 CYS A CA 1 ATOM 276 C C . CYS A 1 87 ? -12.295 -8.743 30.798 1.00 48.88 ? 60 CYS A C 1 ATOM 277 O O . CYS A 1 87 ? -11.172 -9.211 30.894 1.00 48.77 ? 60 CYS A O 1 ATOM 278 C CB . CYS A 1 87 ? -12.837 -8.078 28.444 1.00 52.93 ? 60 CYS A CB 1 ATOM 279 S SG . CYS A 1 87 ? -13.383 -6.714 27.386 1.00 54.65 ? 60 CYS A SG 1 ATOM 280 N N . ILE A 1 88 ? -13.328 -9.209 31.485 1.00 45.60 ? 61 ILE A N 1 ATOM 281 C CA . ILE A 1 88 ? -13.162 -10.279 32.452 1.00 44.63 ? 61 ILE A CA 1 ATOM 282 C C . ILE A 1 88 ? -14.314 -11.275 32.354 1.00 44.83 ? 61 ILE A C 1 ATOM 283 O O . ILE A 1 88 ? -15.432 -10.933 31.899 1.00 40.37 ? 61 ILE A O 1 ATOM 284 C CB . ILE A 1 88 ? -13.003 -9.762 33.896 1.00 47.35 ? 61 ILE A CB 1 ATOM 285 C CG1 . ILE A 1 88 ? -14.223 -8.952 34.319 1.00 49.91 ? 61 ILE A CG1 1 ATOM 286 C CG2 . ILE A 1 88 ? -11.728 -8.943 34.014 1.00 51.72 ? 61 ILE A CG2 1 ATOM 287 C CD1 . ILE A 1 88 ? -14.359 -8.766 35.824 1.00 50.12 ? 61 ILE A CD1 1 ATOM 288 N N . ARG A 1 89 ? -14.000 -12.496 32.777 1.00 41.31 ? 62 ARG A N 1 ATOM 289 C CA . ARG A 1 89 ? -14.926 -13.605 32.901 1.00 44.59 ? 62 ARG A CA 1 ATOM 290 C C . ARG A 1 89 ? -15.341 -14.166 31.553 1.00 44.22 ? 62 ARG A C 1 ATOM 291 O O . ARG A 1 89 ? -16.273 -13.670 30.916 1.00 43.04 ? 62 ARG A O 1 ATOM 292 C CB . ARG A 1 89 ? -16.146 -13.232 33.741 1.00 45.22 ? 62 ARG A CB 1 ATOM 293 C CG . ARG A 1 89 ? -15.786 -12.975 35.189 1.00 50.25 ? 62 ARG A CG 1 ATOM 294 C CD . ARG A 1 89 ? -17.023 -13.004 36.095 1.00 54.88 ? 62 ARG A CD 1 ATOM 295 N NE . ARG A 1 89 ? -17.911 -11.911 35.709 1.00 57.42 ? 62 ARG A NE 1 ATOM 296 C CZ . ARG A 1 89 ? -19.235 -11.920 35.809 1.00 63.69 ? 62 ARG A CZ 1 ATOM 297 N NH1 . ARG A 1 89 ? -19.894 -12.978 36.291 1.00 65.18 ? 62 ARG A NH1 1 ATOM 298 N NH2 . ARG A 1 89 ? -19.913 -10.848 35.406 1.00 64.17 ? 62 ARG A NH2 1 ATOM 299 N N . TYR A 1 90 ? -14.662 -15.240 31.157 1.00 45.52 ? 63 TYR A N 1 ATOM 300 C CA . TYR A 1 90 ? -14.863 -15.830 29.848 1.00 43.68 ? 63 TYR A CA 1 ATOM 301 C C . TYR A 1 90 ? -16.290 -16.363 29.722 1.00 42.72 ? 63 TYR A C 1 ATOM 302 O O . TYR A 1 90 ? -16.817 -16.970 30.654 1.00 45.02 ? 63 TYR A O 1 ATOM 303 C CB . TYR A 1 90 ? -13.844 -16.936 29.572 1.00 41.74 ? 63 TYR A CB 1 ATOM 304 C CG . TYR A 1 90 ? -13.654 -17.154 28.099 1.00 40.47 ? 63 TYR A CG 1 ATOM 305 C CD1 . TYR A 1 90 ? -12.847 -16.312 27.369 1.00 42.33 ? 63 TYR A CD1 1 ATOM 306 C CD2 . TYR A 1 90 ? -14.324 -18.173 27.420 1.00 42.63 ? 63 TYR A CD2 1 ATOM 307 C CE1 . TYR A 1 90 ? -12.684 -16.475 26.004 1.00 41.52 ? 63 TYR A CE1 1 ATOM 308 C CE2 . TYR A 1 90 ? -14.159 -18.346 26.051 1.00 41.54 ? 63 TYR A CE2 1 ATOM 309 C CZ . TYR A 1 90 ? -13.332 -17.488 25.360 1.00 40.37 ? 63 TYR A CZ 1 ATOM 310 O OH . TYR A 1 90 ? -13.164 -17.621 24.020 1.00 40.06 ? 63 TYR A OH 1 ATOM 311 N N . ASN A 1 91 ? -16.921 -16.087 28.583 1.00 41.55 ? 64 ASN A N 1 ATOM 312 C CA . ASN A 1 91 ? -18.300 -16.508 28.329 1.00 42.40 ? 64 ASN A CA 1 ATOM 313 C C . ASN A 1 91 ? -18.323 -17.610 27.284 1.00 40.33 ? 64 ASN A C 1 ATOM 314 O O . ASN A 1 91 ? -18.380 -17.330 26.083 1.00 37.10 ? 64 ASN A O 1 ATOM 315 C CB . ASN A 1 91 ? -19.133 -15.312 27.847 1.00 41.41 ? 64 ASN A CB 1 ATOM 316 C CG . ASN A 1 91 ? -20.588 -15.670 27.558 1.00 41.16 ? 64 ASN A CG 1 ATOM 317 O OD1 . ASN A 1 91 ? -21.047 -16.782 27.826 1.00 36.37 ? 64 ASN A OD1 1 ATOM 318 N ND2 . ASN A 1 91 ? -21.313 -14.726 26.991 1.00 40.84 ? 64 ASN A ND2 1 ATOM 319 N N . PHE A 1 92 ? -18.300 -18.862 27.739 1.00 38.90 ? 65 PHE A N 1 ATOM 320 C CA . PHE A 1 92 ? -18.172 -19.978 26.806 1.00 40.23 ? 65 PHE A CA 1 ATOM 321 C C . PHE A 1 92 ? -19.350 -20.076 25.849 1.00 37.51 ? 65 PHE A C 1 ATOM 322 O O . PHE A 1 92 ? -19.188 -20.381 24.678 1.00 38.47 ? 65 PHE A O 1 ATOM 323 C CB . PHE A 1 92 ? -17.975 -21.298 27.558 1.00 43.19 ? 65 PHE A CB 1 ATOM 324 C CG . PHE A 1 92 ? -16.623 -21.430 28.194 1.00 42.66 ? 65 PHE A CG 1 ATOM 325 C CD1 . PHE A 1 92 ? -15.497 -21.659 27.414 1.00 43.52 ? 65 PHE A CD1 1 ATOM 326 C CD2 . PHE A 1 92 ? -16.472 -21.327 29.570 1.00 44.30 ? 65 PHE A CD2 1 ATOM 327 C CE1 . PHE A 1 92 ? -14.241 -21.780 27.995 1.00 44.89 ? 65 PHE A CE1 1 ATOM 328 C CE2 . PHE A 1 92 ? -15.221 -21.452 30.160 1.00 45.15 ? 65 PHE A CE2 1 ATOM 329 C CZ . PHE A 1 92 ? -14.105 -21.679 29.371 1.00 45.46 ? 65 PHE A CZ 1 ATOM 330 N N . ARG A 1 93 ? -20.539 -19.786 26.344 1.00 36.43 ? 66 ARG A N 1 ATOM 331 C CA . ARG A 1 93 ? -21.723 -19.825 25.522 1.00 36.25 ? 66 ARG A CA 1 ATOM 332 C C . ARG A 1 93 ? -21.643 -18.778 24.412 1.00 36.49 ? 66 ARG A C 1 ATOM 333 O O . ARG A 1 93 ? -22.049 -19.022 23.287 1.00 35.30 ? 66 ARG A O 1 ATOM 334 C CB . ARG A 1 93 ? -22.950 -19.593 26.401 1.00 35.74 ? 66 ARG A CB 1 ATOM 335 C CG . ARG A 1 93 ? -24.268 -19.694 25.681 1.00 34.06 ? 66 ARG A CG 1 ATOM 336 C CD . ARG A 1 93 ? -25.381 -19.655 26.701 1.00 34.68 ? 66 ARG A CD 1 ATOM 337 N NE . ARG A 1 93 ? -26.686 -19.645 26.061 1.00 36.65 ? 66 ARG A NE 1 ATOM 338 C CZ . ARG A 1 93 ? -27.808 -19.241 26.652 1.00 40.35 ? 66 ARG A CZ 1 ATOM 339 N NH1 . ARG A 1 93 ? -27.784 -18.800 27.909 1.00 41.23 ? 66 ARG A NH1 1 ATOM 340 N NH2 . ARG A 1 93 ? -28.954 -19.258 25.978 1.00 41.74 ? 66 ARG A NH2 1 ATOM 341 N N . GLY A 1 94 ? -21.115 -17.609 24.746 1.00 38.58 ? 67 GLY A N 1 ATOM 342 C CA . GLY A 1 94 ? -20.948 -16.537 23.773 1.00 39.94 ? 67 GLY A CA 1 ATOM 343 C C . GLY A 1 94 ? -19.958 -16.897 22.685 1.00 37.98 ? 67 GLY A C 1 ATOM 344 O O . GLY A 1 94 ? -20.137 -16.525 21.520 1.00 37.65 ? 67 GLY A O 1 ATOM 345 N N . PHE A 1 95 ? -18.895 -17.589 23.071 1.00 37.91 ? 68 PHE A N 1 ATOM 346 C CA . PHE A 1 95 ? -17.906 -18.063 22.099 1.00 39.56 ? 68 PHE A CA 1 ATOM 347 C C . PHE A 1 95 ? -18.530 -19.083 21.169 1.00 37.04 ? 68 PHE A C 1 ATOM 348 O O . PHE A 1 95 ? -18.253 -19.079 19.980 1.00 38.69 ? 68 PHE A O 1 ATOM 349 C CB . PHE A 1 95 ? -16.702 -18.677 22.797 1.00 41.68 ? 68 PHE A CB 1 ATOM 350 C CG . PHE A 1 95 ? -15.642 -19.142 21.854 1.00 44.88 ? 68 PHE A CG 1 ATOM 351 C CD1 . PHE A 1 95 ? -14.924 -18.233 21.094 1.00 44.47 ? 68 PHE A CD1 1 ATOM 352 C CD2 . PHE A 1 95 ? -15.368 -20.492 21.712 1.00 46.93 ? 68 PHE A CD2 1 ATOM 353 C CE1 . PHE A 1 95 ? -13.938 -18.669 20.230 1.00 44.89 ? 68 PHE A CE1 1 ATOM 354 C CE2 . PHE A 1 95 ? -14.395 -20.932 20.833 1.00 46.47 ? 68 PHE A CE2 1 ATOM 355 C CZ . PHE A 1 95 ? -13.676 -20.023 20.093 1.00 43.78 ? 68 PHE A CZ 1 ATOM 356 N N . ARG A 1 96 ? -19.418 -19.918 21.706 1.00 36.63 ? 69 ARG A N 1 ATOM 357 C CA . ARG A 1 96 ? -20.207 -20.822 20.881 1.00 35.32 ? 69 ARG A CA 1 ATOM 358 C C . ARG A 1 96 ? -21.093 -20.063 19.910 1.00 37.71 ? 69 ARG A C 1 ATOM 359 O O . ARG A 1 96 ? -21.220 -20.451 18.729 1.00 38.33 ? 69 ARG A O 1 ATOM 360 C CB . ARG A 1 96 ? -21.054 -21.788 21.740 1.00 37.74 ? 69 ARG A CB 1 ATOM 361 C CG . ARG A 1 96 ? -22.141 -22.498 20.932 1.00 36.07 ? 69 ARG A CG 1 ATOM 362 C CD . ARG A 1 96 ? -22.646 -23.784 21.536 1.00 37.95 ? 69 ARG A CD 1 ATOM 363 N NE . ARG A 1 96 ? -22.953 -23.740 22.966 1.00 39.54 ? 69 ARG A NE 1 ATOM 364 C CZ . ARG A 1 96 ? -24.074 -23.263 23.494 1.00 39.39 ? 69 ARG A CZ 1 ATOM 365 N NH1 . ARG A 1 96 ? -25.010 -22.720 22.733 1.00 40.40 ? 69 ARG A NH1 1 ATOM 366 N NH2 . ARG A 1 96 ? -24.231 -23.275 24.799 1.00 41.12 ? 69 ARG A NH2 1 ATOM 367 N N . TRP A 1 97 ? -21.726 -18.989 20.381 1.00 35.11 ? 70 TRP A N 1 ATOM 368 C CA . TRP A 1 97 ? -22.519 -18.143 19.472 1.00 36.20 ? 70 TRP A CA 1 ATOM 369 C C . TRP A 1 97 ? -21.674 -17.609 18.328 1.00 33.59 ? 70 TRP A C 1 ATOM 370 O O . TRP A 1 97 ? -22.105 -17.625 17.181 1.00 32.49 ? 70 TRP A O 1 ATOM 371 C CB . TRP A 1 97 ? -23.169 -16.957 20.206 1.00 36.82 ? 70 TRP A CB 1 ATOM 372 C CG . TRP A 1 97 ? -24.175 -17.351 21.231 1.00 36.05 ? 70 TRP A CG 1 ATOM 373 C CD1 . TRP A 1 97 ? -24.720 -18.576 21.424 1.00 38.48 ? 70 TRP A CD1 1 ATOM 374 C CD2 . TRP A 1 97 ? -24.774 -16.490 22.182 1.00 37.35 ? 70 TRP A CD2 1 ATOM 375 N NE1 . TRP A 1 97 ? -25.613 -18.545 22.468 1.00 36.87 ? 70 TRP A NE1 1 ATOM 376 C CE2 . TRP A 1 97 ? -25.663 -17.265 22.948 1.00 37.80 ? 70 TRP A CE2 1 ATOM 377 C CE3 . TRP A 1 97 ? -24.637 -15.131 22.471 1.00 35.81 ? 70 TRP A CE3 1 ATOM 378 C CZ2 . TRP A 1 97 ? -26.403 -16.726 23.988 1.00 40.14 ? 70 TRP A CZ2 1 ATOM 379 C CZ3 . TRP A 1 97 ? -25.372 -14.603 23.492 1.00 38.13 ? 70 TRP A CZ3 1 ATOM 380 C CH2 . TRP A 1 97 ? -26.237 -15.393 24.247 1.00 37.02 ? 70 TRP A CH2 1 ATOM 381 N N . LEU A 1 98 ? -20.488 -17.115 18.655 1.00 33.19 ? 71 LEU A N 1 ATOM 382 C CA . LEU A 1 98 ? -19.601 -16.583 17.644 1.00 36.31 ? 71 LEU A CA 1 ATOM 383 C C . LEU A 1 98 ? -19.244 -17.691 16.640 1.00 38.66 ? 71 LEU A C 1 ATOM 384 O O . LEU A 1 98 ? -19.144 -17.439 15.440 1.00 36.49 ? 71 LEU A O 1 ATOM 385 C CB . LEU A 1 98 ? -18.336 -16.031 18.298 1.00 37.87 ? 71 LEU A CB 1 ATOM 386 C CG . LEU A 1 98 ? -17.204 -15.564 17.388 1.00 38.82 ? 71 LEU A CG 1 ATOM 387 C CD1 . LEU A 1 98 ? -16.407 -14.452 18.061 1.00 39.43 ? 71 LEU A CD1 1 ATOM 388 C CD2 . LEU A 1 98 ? -16.260 -16.708 17.020 1.00 42.45 ? 71 LEU A CD2 1 ATOM 389 N N . GLN A 1 99 ? -19.061 -18.910 17.147 1.00 40.68 ? 72 GLN A N 1 ATOM 390 C CA . GLN A 1 99 ? -18.765 -20.063 16.290 1.00 43.60 ? 72 GLN A CA 1 ATOM 391 C C . GLN A 1 99 ? -19.890 -20.360 15.300 1.00 46.35 ? 72 GLN A C 1 ATOM 392 O O . GLN A 1 99 ? -19.619 -20.738 14.153 1.00 44.59 ? 72 GLN A O 1 ATOM 393 C CB . GLN A 1 99 ? -18.440 -21.311 17.127 1.00 42.37 ? 72 GLN A CB 1 ATOM 394 C CG . GLN A 1 99 ? -17.101 -21.249 17.855 1.00 43.17 ? 72 GLN A CG 1 ATOM 395 C CD . GLN A 1 99 ? -15.925 -21.674 16.984 1.00 48.03 ? 72 GLN A CD 1 ATOM 396 O OE1 . GLN A 1 99 ? -15.295 -22.708 17.233 1.00 55.69 ? 72 GLN A OE1 1 ATOM 397 N NE2 . GLN A 1 99 ? -15.632 -20.900 15.963 1.00 43.90 ? 72 GLN A NE2 1 ATOM 398 N N . ALA A 1 100 ? -21.138 -20.193 15.740 1.00 44.52 ? 73 ALA A N 1 ATOM 399 C CA . ALA A 1 100 ? -22.287 -20.435 14.880 1.00 44.16 ? 73 ALA A CA 1 ATOM 400 C C . ALA A 1 100 ? -22.307 -19.493 13.684 1.00 43.85 ? 73 ALA A C 1 ATOM 401 O O . ALA A 1 100 ? -22.780 -19.857 12.613 1.00 40.91 ? 73 ALA A O 1 ATOM 402 C CB . ALA A 1 100 ? -23.576 -20.313 15.667 1.00 48.90 ? 73 ALA A CB 1 ATOM 403 N N . MET A 1 101 ? -21.777 -18.287 13.860 1.00 41.81 ? 74 MET A N 1 ATOM 404 C CA . MET A 1 101 ? -21.667 -17.353 12.756 1.00 39.49 ? 74 MET A CA 1 ATOM 405 C C . MET A 1 101 ? -20.581 -17.818 11.779 1.00 40.39 ? 74 MET A C 1 ATOM 406 O O . MET A 1 101 ? -20.801 -17.801 10.581 1.00 39.90 ? 74 MET A O 1 ATOM 407 C CB . MET A 1 101 ? -21.342 -15.945 13.265 1.00 36.72 ? 74 MET A CB 1 ATOM 408 C CG . MET A 1 101 ? -21.007 -14.957 12.167 1.00 37.22 ? 74 MET A CG 1 ATOM 409 S SD . MET A 1 101 ? -21.028 -13.225 12.687 1.00 37.55 ? 74 MET A SD 1 ATOM 410 C CE . MET A 1 101 ? -20.572 -12.415 11.163 1.00 37.46 ? 74 MET A CE 1 ATOM 411 N N . ILE A 1 102 ? -19.402 -18.160 12.299 1.00 42.67 ? 75 ILE A N 1 ATOM 412 C CA . ILE A 1 102 ? -18.306 -18.621 11.454 1.00 46.26 ? 75 ILE A CA 1 ATOM 413 C C . ILE A 1 102 ? -18.735 -19.890 10.721 1.00 46.19 ? 75 ILE A C 1 ATOM 414 O O . ILE A 1 102 ? -18.505 -20.010 9.531 1.00 51.59 ? 75 ILE A O 1 ATOM 415 C CB . ILE A 1 102 ? -16.997 -18.853 12.250 1.00 47.17 ? 75 ILE A CB 1 ATOM 416 C CG1 . ILE A 1 102 ? -16.426 -17.519 12.759 1.00 46.61 ? 75 ILE A CG1 1 ATOM 417 C CG2 . ILE A 1 102 ? -15.931 -19.534 11.381 1.00 46.88 ? 75 ILE A CG2 1 ATOM 418 C CD1 . ILE A 1 102 ? -15.311 -17.663 13.777 1.00 45.34 ? 75 ILE A CD1 1 ATOM 419 N N . PHE A 1 103 ? -19.375 -20.814 11.431 1.00 48.44 ? 76 PHE A N 1 ATOM 420 C CA . PHE A 1 103 ? -19.888 -22.036 10.829 1.00 50.55 ? 76 PHE A CA 1 ATOM 421 C C . PHE A 1 103 ? -20.843 -21.751 9.672 1.00 49.54 ? 76 PHE A C 1 ATOM 422 O O . PHE A 1 103 ? -20.708 -22.336 8.596 1.00 48.25 ? 76 PHE A O 1 ATOM 423 C CB . PHE A 1 103 ? -20.604 -22.890 11.878 1.00 52.77 ? 76 PHE A CB 1 ATOM 424 C CG . PHE A 1 103 ? -21.210 -24.153 11.326 1.00 53.41 ? 76 PHE A CG 1 ATOM 425 C CD1 . PHE A 1 103 ? -20.425 -25.286 11.124 1.00 51.92 ? 76 PHE A CD1 1 ATOM 426 C CD2 . PHE A 1 103 ? -22.567 -24.211 10.996 1.00 53.38 ? 76 PHE A CD2 1 ATOM 427 C CE1 . PHE A 1 103 ? -20.980 -26.450 10.605 1.00 49.52 ? 76 PHE A CE1 1 ATOM 428 C CE2 . PHE A 1 103 ? -23.122 -25.369 10.469 1.00 53.34 ? 76 PHE A CE2 1 ATOM 429 C CZ . PHE A 1 103 ? -22.324 -26.494 10.279 1.00 50.51 ? 76 PHE A CZ 1 ATOM 430 N N . ALA A 1 104 ? -21.814 -20.868 9.894 1.00 46.72 ? 77 ALA A N 1 ATOM 431 C CA . ALA A 1 104 ? -22.803 -20.547 8.858 1.00 44.12 ? 77 ALA A CA 1 ATOM 432 C C . ALA A 1 104 ? -22.129 -19.995 7.618 1.00 44.05 ? 77 ALA A C 1 ATOM 433 O O . ALA A 1 104 ? -22.545 -20.297 6.499 1.00 39.39 ? 77 ALA A O 1 ATOM 434 C CB . ALA A 1 104 ? -23.834 -19.561 9.371 1.00 43.77 ? 77 ALA A CB 1 ATOM 435 N N . ILE A 1 105 ? -21.106 -19.171 7.822 1.00 41.67 ? 78 ILE A N 1 ATOM 436 C CA . ILE A 1 105 ? -20.415 -18.527 6.704 1.00 44.70 ? 78 ILE A CA 1 ATOM 437 C C . ILE A 1 105 ? -19.573 -19.540 5.904 1.00 47.76 ? 78 ILE A C 1 ATOM 438 O O . ILE A 1 105 ? -19.539 -19.476 4.688 1.00 47.09 ? 78 ILE A O 1 ATOM 439 C CB . ILE A 1 105 ? -19.524 -17.364 7.188 1.00 43.54 ? 78 ILE A CB 1 ATOM 440 C CG1 . ILE A 1 105 ? -20.387 -16.153 7.529 1.00 43.35 ? 78 ILE A CG1 1 ATOM 441 C CG2 . ILE A 1 105 ? -18.504 -16.957 6.141 1.00 43.36 ? 78 ILE A CG2 1 ATOM 442 C CD1 . ILE A 1 105 ? -19.668 -15.140 8.390 1.00 44.19 ? 78 ILE A CD1 1 ATOM 443 N N . GLU A 1 106 ? -18.897 -20.451 6.597 1.00 51.02 ? 79 GLU A N 1 ATOM 444 C CA . GLU A 1 106 ? -18.121 -21.497 5.926 1.00 54.11 ? 79 GLU A CA 1 ATOM 445 C C . GLU A 1 106 ? -19.055 -22.421 5.141 1.00 56.21 ? 79 GLU A C 1 ATOM 446 O O . GLU A 1 106 ? -18.817 -22.692 3.974 1.00 62.74 ? 79 GLU A O 1 ATOM 447 C CB . GLU A 1 106 ? -17.274 -22.277 6.925 1.00 53.84 ? 79 GLU A CB 1 ATOM 448 C CG . GLU A 1 106 ? -16.123 -21.454 7.506 1.00 57.58 ? 79 GLU A CG 1 ATOM 449 C CD . GLU A 1 106 ? -15.185 -22.255 8.408 1.00 60.21 ? 79 GLU A CD 1 ATOM 450 O OE1 . GLU A 1 106 ? -15.388 -23.480 8.567 1.00 63.20 ? 79 GLU A OE1 1 ATOM 451 O OE2 . GLU A 1 106 ? -14.241 -21.658 8.974 1.00 59.60 ? 79 GLU A OE2 1 ATOM 452 N N . GLU A 1 107 ? -20.150 -22.837 5.768 1.00 56.43 ? 80 GLU A N 1 ATOM 453 C CA . GLU A 1 107 ? -21.204 -23.611 5.103 1.00 57.14 ? 80 GLU A CA 1 ATOM 454 C C . GLU A 1 107 ? -21.752 -22.941 3.834 1.00 58.77 ? 80 GLU A C 1 ATOM 455 O O . GLU A 1 107 ? -21.998 -23.597 2.816 1.00 62.61 ? 80 GLU A O 1 ATOM 456 C CB . GLU A 1 107 ? -22.360 -23.850 6.079 1.00 56.44 ? 80 GLU A CB 1 ATOM 457 C CG . GLU A 1 107 ? -23.401 -24.843 5.605 1.00 53.91 ? 80 GLU A CG 1 ATOM 458 C CD . GLU A 1 107 ? -24.425 -25.135 6.676 1.00 57.00 ? 80 GLU A CD 1 ATOM 459 O OE1 . GLU A 1 107 ? -25.339 -24.304 6.860 1.00 61.69 ? 80 GLU A OE1 1 ATOM 460 O OE2 . GLU A 1 107 ? -24.322 -26.188 7.333 1.00 53.47 ? 80 GLU A OE2 1 ATOM 461 N N . ILE A 1 108 ? -21.989 -21.641 3.910 1.00 58.42 ? 81 ILE A N 1 ATOM 462 C CA . ILE A 1 108 ? -22.517 -20.904 2.769 1.00 59.86 ? 81 ILE A CA 1 ATOM 463 C C . ILE A 1 108 ? -21.481 -20.865 1.655 1.00 56.76 ? 81 ILE A C 1 ATOM 464 O O . ILE A 1 108 ? -21.804 -21.100 0.487 1.00 55.59 ? 81 ILE A O 1 ATOM 465 C CB . ILE A 1 108 ? -22.939 -19.475 3.177 1.00 58.64 ? 81 ILE A CB 1 ATOM 466 C CG1 . ILE A 1 108 ? -24.244 -19.542 3.981 1.00 58.62 ? 81 ILE A CG1 1 ATOM 467 C CG2 . ILE A 1 108 ? -23.122 -18.578 1.955 1.00 55.70 ? 81 ILE A CG2 1 ATOM 468 C CD1 . ILE A 1 108 ? -24.470 -18.321 4.845 1.00 62.06 ? 81 ILE A CD1 1 ATOM 469 N N . ASN A 1 109 ? -20.244 -20.568 2.029 1.00 56.21 ? 82 ASN A N 1 ATOM 470 C CA . ASN A 1 109 ? -19.140 -20.555 1.082 1.00 60.68 ? 82 ASN A CA 1 ATOM 471 C C . ASN A 1 109 ? -18.885 -21.924 0.443 1.00 64.82 ? 82 ASN A C 1 ATOM 472 O O . ASN A 1 109 ? -18.445 -22.000 -0.696 1.00 70.07 ? 82 ASN A O 1 ATOM 473 C CB . ASN A 1 109 ? -17.867 -20.053 1.759 1.00 56.44 ? 82 ASN A CB 1 ATOM 474 C CG . ASN A 1 109 ? -17.869 -18.550 1.959 1.00 58.00 ? 82 ASN A CG 1 ATOM 475 O OD1 . ASN A 1 109 ? -18.618 -17.796 1.299 1.00 51.39 ? 82 ASN A OD1 1 ATOM 476 N ND2 . ASN A 1 109 ? -17.009 -18.094 2.858 1.00 58.22 ? 82 ASN A ND2 1 ATOM 477 N N . SER A 1 110 ? -19.176 -22.989 1.185 1.00 65.39 ? 83 SER A N 1 ATOM 478 C CA . SER A 1 110 ? -19.101 -24.353 0.671 1.00 66.98 ? 83 SER A CA 1 ATOM 479 C C . SER A 1 110 ? -20.282 -24.748 -0.208 1.00 71.17 ? 83 SER A C 1 ATOM 480 O O . SER A 1 110 ? -20.265 -25.812 -0.806 1.00 77.02 ? 83 SER A O 1 ATOM 481 C CB . SER A 1 110 ? -19.000 -25.340 1.829 1.00 66.23 ? 83 SER A CB 1 ATOM 482 O OG . SER A 1 110 ? -17.714 -25.264 2.408 1.00 64.64 ? 83 SER A OG 1 ATOM 483 N N . SER A 1 111 ? -21.311 -23.915 -0.279 1.00 78.43 ? 84 SER A N 1 ATOM 484 C CA . SER A 1 111 ? -22.484 -24.231 -1.071 1.00 81.35 ? 84 SER A CA 1 ATOM 485 C C . SER A 1 111 ? -22.323 -23.625 -2.455 1.00 87.36 ? 84 SER A C 1 ATOM 486 O O . SER A 1 111 ? -22.177 -22.407 -2.601 1.00 89.40 ? 84 SER A O 1 ATOM 487 C CB . SER A 1 111 ? -23.758 -23.708 -0.410 1.00 80.44 ? 84 SER A CB 1 ATOM 488 O OG . SER A 1 111 ? -24.895 -24.104 -1.157 1.00 86.67 ? 84 SER A OG 1 ATOM 489 N N . PRO A 1 112 ? -22.345 -24.475 -3.485 1.00 94.73 ? 85 PRO A N 1 ATOM 490 C CA . PRO A 1 112 ? -22.207 -23.949 -4.838 1.00 93.93 ? 85 PRO A CA 1 ATOM 491 C C . PRO A 1 112 ? -23.430 -23.123 -5.244 1.00 89.00 ? 85 PRO A C 1 ATOM 492 O O . PRO A 1 112 ? -23.286 -22.093 -5.898 1.00 80.25 ? 85 PRO A O 1 ATOM 493 C CB . PRO A 1 112 ? -22.083 -25.215 -5.689 1.00 97.44 ? 85 PRO A CB 1 ATOM 494 C CG . PRO A 1 112 ? -22.815 -26.271 -4.918 1.00 98.47 ? 85 PRO A CG 1 ATOM 495 C CD . PRO A 1 112 ? -22.691 -25.911 -3.465 1.00 94.92 ? 85 PRO A CD 1 ATOM 496 N N . ALA A 1 113 ? -24.612 -23.582 -4.826 1.00 89.47 ? 86 ALA A N 1 ATOM 497 C CA . ALA A 1 113 ? -25.896 -22.967 -5.170 1.00 89.19 ? 86 ALA A CA 1 ATOM 498 C C . ALA A 1 113 ? -26.007 -21.532 -4.674 1.00 88.13 ? 86 ALA A C 1 ATOM 499 O O . ALA A 1 113 ? -26.317 -20.614 -5.435 1.00 87.17 ? 86 ALA A O 1 ATOM 500 C CB . ALA A 1 113 ? -27.033 -23.794 -4.575 1.00 88.42 ? 86 ALA A CB 1 ATOM 501 N N . LEU A 1 114 ? -25.745 -21.362 -3.384 1.00 86.49 ? 87 LEU A N 1 ATOM 502 C CA . LEU A 1 114 ? -25.956 -20.097 -2.703 1.00 78.29 ? 87 LEU A CA 1 ATOM 503 C C . LEU A 1 114 ? -24.752 -19.181 -2.915 1.00 70.44 ? 87 LEU A C 1 ATOM 504 O O . LEU A 1 114 ? -23.646 -19.496 -2.471 1.00 71.25 ? 87 LEU A O 1 ATOM 505 C CB . LEU A 1 114 ? -26.167 -20.380 -1.215 1.00 77.50 ? 87 LEU A CB 1 ATOM 506 C CG . LEU A 1 114 ? -26.831 -19.315 -0.354 1.00 78.42 ? 87 LEU A CG 1 ATOM 507 C CD1 . LEU A 1 114 ? -28.213 -18.941 -0.876 1.00 79.47 ? 87 LEU A CD1 1 ATOM 508 C CD2 . LEU A 1 114 ? -26.902 -19.846 1.068 1.00 77.63 ? 87 LEU A CD2 1 ATOM 509 N N . LEU A 1 115 ? -24.975 -18.066 -3.610 1.00 67.61 ? 88 LEU A N 1 ATOM 510 C CA . LEU A 1 115 ? -23.922 -17.078 -3.914 1.00 70.91 ? 88 LEU A CA 1 ATOM 511 C C . LEU A 1 115 ? -22.698 -17.679 -4.612 1.00 76.28 ? 88 LEU A C 1 ATOM 512 O O . LEU A 1 115 ? -21.591 -17.690 -4.058 1.00 72.47 ? 88 LEU A O 1 ATOM 513 C CB . LEU A 1 115 ? -23.477 -16.332 -2.652 1.00 69.27 ? 88 LEU A CB 1 ATOM 514 C CG . LEU A 1 115 ? -24.525 -15.511 -1.901 1.00 66.88 ? 88 LEU A CG 1 ATOM 515 C CD1 . LEU A 1 115 ? -23.871 -14.904 -0.666 1.00 65.32 ? 88 LEU A CD1 1 ATOM 516 C CD2 . LEU A 1 115 ? -25.133 -14.437 -2.794 1.00 67.82 ? 88 LEU A CD2 1 ATOM 517 N N . PRO A 1 116 ? -22.891 -18.155 -5.852 1.00 82.10 ? 89 PRO A N 1 ATOM 518 C CA . PRO A 1 116 ? -21.834 -18.887 -6.556 1.00 81.88 ? 89 PRO A CA 1 ATOM 519 C C . PRO A 1 116 ? -20.625 -18.020 -6.925 1.00 75.74 ? 89 PRO A C 1 ATOM 520 O O . PRO A 1 116 ? -19.486 -18.455 -6.758 1.00 75.83 ? 89 PRO A O 1 ATOM 521 C CB . PRO A 1 116 ? -22.542 -19.407 -7.809 1.00 84.09 ? 89 PRO A CB 1 ATOM 522 C CG . PRO A 1 116 ? -23.679 -18.476 -8.021 1.00 82.83 ? 89 PRO A CG 1 ATOM 523 C CD . PRO A 1 116 ? -24.111 -18.010 -6.666 1.00 80.83 ? 89 PRO A CD 1 ATOM 524 N N . ASN A 1 117 ? -20.858 -16.802 -7.398 1.00 69.28 ? 90 ASN A N 1 ATOM 525 C CA . ASN A 1 117 ? -19.751 -15.942 -7.799 1.00 71.40 ? 90 ASN A CA 1 ATOM 526 C C . ASN A 1 117 ? -18.824 -15.530 -6.641 1.00 75.81 ? 90 ASN A C 1 ATOM 527 O O . ASN A 1 117 ? -17.642 -15.259 -6.869 1.00 75.94 ? 90 ASN A O 1 ATOM 528 C CB . ASN A 1 117 ? -20.282 -14.686 -8.499 1.00 71.34 ? 90 ASN A CB 1 ATOM 529 N N . LEU A 1 118 ? -19.343 -15.523 -5.405 1.00 75.95 ? 91 LEU A N 1 ATOM 530 C CA . LEU A 1 118 ? -18.744 -14.750 -4.305 1.00 66.09 ? 91 LEU A CA 1 ATOM 531 C C . LEU A 1 118 ? -18.428 -15.515 -3.017 1.00 61.66 ? 91 LEU A C 1 ATOM 532 O O . LEU A 1 118 ? -19.028 -16.538 -2.717 1.00 62.35 ? 91 LEU A O 1 ATOM 533 C CB . LEU A 1 118 ? -19.680 -13.585 -3.980 1.00 64.50 ? 91 LEU A CB 1 ATOM 534 N N . THR A 1 119 ? -17.462 -15.007 -2.261 1.00 62.03 ? 92 THR A N 1 ATOM 535 C CA . THR A 1 119 ? -17.162 -15.515 -0.914 1.00 65.24 ? 92 THR A CA 1 ATOM 536 C C . THR A 1 119 ? -17.554 -14.487 0.153 1.00 63.47 ? 92 THR A C 1 ATOM 537 O O . THR A 1 119 ? -17.256 -13.291 0.023 1.00 59.46 ? 92 THR A O 1 ATOM 538 C CB . THR A 1 119 ? -15.661 -15.793 -0.728 1.00 68.91 ? 92 THR A CB 1 ATOM 539 O OG1 . THR A 1 119 ? -14.925 -14.582 -0.953 1.00 72.16 ? 92 THR A OG1 1 ATOM 540 C CG2 . THR A 1 119 ? -15.193 -16.884 -1.687 1.00 70.89 ? 92 THR A CG2 1 ATOM 541 N N . LEU A 1 120 ? -18.195 -14.970 1.214 1.00 57.45 ? 93 LEU A N 1 ATOM 542 C CA . LEU A 1 120 ? -18.442 -14.150 2.394 1.00 54.01 ? 93 LEU A CA 1 ATOM 543 C C . LEU A 1 120 ? -17.268 -14.242 3.361 1.00 51.08 ? 93 LEU A C 1 ATOM 544 O O . LEU A 1 120 ? -16.874 -15.337 3.758 1.00 52.21 ? 93 LEU A O 1 ATOM 545 C CB . LEU A 1 120 ? -19.705 -14.619 3.108 1.00 51.83 ? 93 LEU A CB 1 ATOM 546 C CG . LEU A 1 120 ? -21.023 -14.546 2.333 1.00 50.86 ? 93 LEU A CG 1 ATOM 547 C CD1 . LEU A 1 120 ? -22.144 -14.992 3.252 1.00 51.16 ? 93 LEU A CD1 1 ATOM 548 C CD2 . LEU A 1 120 ? -21.306 -13.157 1.787 1.00 51.02 ? 93 LEU A CD2 1 ATOM 549 N N . GLY A 1 121 ? -16.706 -13.098 3.732 1.00 48.66 ? 94 GLY A N 1 ATOM 550 C CA . GLY A 1 121 ? -15.744 -13.021 4.855 1.00 48.28 ? 94 GLY A CA 1 ATOM 551 C C . GLY A 1 121 ? -16.377 -12.434 6.115 1.00 46.06 ? 94 GLY A C 1 ATOM 552 O O . GLY A 1 121 ? -17.580 -12.183 6.152 1.00 45.81 ? 94 GLY A O 1 ATOM 553 N N . TYR A 1 122 ? -15.562 -12.189 7.135 1.00 46.30 ? 95 TYR A N 1 ATOM 554 C CA . TYR A 1 122 ? -16.075 -11.676 8.380 1.00 48.09 ? 95 TYR A CA 1 ATOM 555 C C . TYR A 1 122 ? -15.057 -10.939 9.229 1.00 50.93 ? 95 TYR A C 1 ATOM 556 O O . TYR A 1 122 ? -13.835 -11.100 9.072 1.00 48.35 ? 95 TYR A O 1 ATOM 557 C CB . TYR A 1 122 ? -16.681 -12.811 9.186 1.00 46.23 ? 95 TYR A CB 1 ATOM 558 C CG . TYR A 1 122 ? -15.748 -13.970 9.448 1.00 49.93 ? 95 TYR A CG 1 ATOM 559 C CD1 . TYR A 1 122 ? -14.804 -13.917 10.481 1.00 50.06 ? 95 TYR A CD1 1 ATOM 560 C CD2 . TYR A 1 122 ? -15.832 -15.144 8.694 1.00 50.28 ? 95 TYR A CD2 1 ATOM 561 C CE1 . TYR A 1 122 ? -13.965 -14.990 10.753 1.00 50.39 ? 95 TYR A CE1 1 ATOM 562 C CE2 . TYR A 1 122 ? -14.996 -16.228 8.962 1.00 47.77 ? 95 TYR A CE2 1 ATOM 563 C CZ . TYR A 1 122 ? -14.062 -16.143 9.987 1.00 48.54 ? 95 TYR A CZ 1 ATOM 564 O OH . TYR A 1 122 ? -13.218 -17.194 10.276 1.00 45.57 ? 95 TYR A OH 1 ATOM 565 N N . ARG A 1 123 ? -15.597 -10.108 10.122 1.00 50.91 ? 96 ARG A N 1 ATOM 566 C CA . ARG A 1 123 ? -14.813 -9.319 11.069 1.00 51.07 ? 96 ARG A CA 1 ATOM 567 C C . ARG A 1 123 ? -15.630 -9.242 12.355 1.00 45.75 ? 96 ARG A C 1 ATOM 568 O O . ARG A 1 123 ? -16.620 -8.503 12.422 1.00 43.73 ? 96 ARG A O 1 ATOM 569 C CB . ARG A 1 123 ? -14.559 -7.922 10.515 1.00 57.35 ? 96 ARG A CB 1 ATOM 570 C CG . ARG A 1 123 ? -13.113 -7.472 10.582 1.00 68.05 ? 96 ARG A CG 1 ATOM 571 C CD . ARG A 1 123 ? -13.023 -5.962 10.333 1.00 76.14 ? 96 ARG A CD 1 ATOM 572 N NE . ARG A 1 123 ? -13.499 -5.650 8.986 1.00 82.42 ? 96 ARG A NE 1 ATOM 573 C CZ . ARG A 1 123 ? -14.053 -4.494 8.614 1.00 87.32 ? 96 ARG A CZ 1 ATOM 574 N NH1 . ARG A 1 123 ? -14.218 -3.477 9.467 1.00 83.13 ? 96 ARG A NH1 1 ATOM 575 N NH2 . ARG A 1 123 ? -14.457 -4.356 7.356 1.00 92.36 ? 96 ARG A NH2 1 ATOM 576 N N . ILE A 1 124 ? -15.206 -10.002 13.356 1.00 40.55 ? 97 ILE A N 1 ATOM 577 C CA . ILE A 1 124 ? -16.011 -10.278 14.529 1.00 39.91 ? 97 ILE A CA 1 ATOM 578 C C . ILE A 1 124 ? -15.277 -9.875 15.790 1.00 40.72 ? 97 ILE A C 1 ATOM 579 O O . ILE A 1 124 ? -14.133 -10.267 15.999 1.00 39.11 ? 97 ILE A O 1 ATOM 580 C CB . ILE A 1 124 ? -16.362 -11.776 14.612 1.00 40.17 ? 97 ILE A CB 1 ATOM 581 C CG1 . ILE A 1 124 ? -17.052 -12.241 13.319 1.00 38.10 ? 97 ILE A CG1 1 ATOM 582 C CG2 . ILE A 1 124 ? -17.243 -12.032 15.831 1.00 40.99 ? 97 ILE A CG2 1 ATOM 583 C CD1 . ILE A 1 124 ? -17.330 -13.732 13.270 1.00 39.26 ? 97 ILE A CD1 1 ATOM 584 N N . PHE A 1 125 ? -15.950 -9.082 16.623 1.00 41.10 ? 98 PHE A N 1 ATOM 585 C CA . PHE A 1 125 ? -15.356 -8.482 17.806 1.00 37.78 ? 98 PHE A CA 1 ATOM 586 C C . PHE A 1 125 ? -16.117 -8.864 19.060 1.00 37.61 ? 98 PHE A C 1 ATOM 587 O O . PHE A 1 125 ? -17.301 -9.166 19.007 1.00 37.14 ? 98 PHE A O 1 ATOM 588 C CB . PHE A 1 125 ? -15.351 -6.955 17.675 1.00 40.03 ? 98 PHE A CB 1 ATOM 589 C CG . PHE A 1 125 ? -14.492 -6.436 16.556 1.00 43.94 ? 98 PHE A CG 1 ATOM 590 C CD1 . PHE A 1 125 ? -13.113 -6.335 16.715 1.00 46.64 ? 98 PHE A CD1 1 ATOM 591 C CD2 . PHE A 1 125 ? -15.055 -6.019 15.357 1.00 43.48 ? 98 PHE A CD2 1 ATOM 592 C CE1 . PHE A 1 125 ? -12.317 -5.860 15.681 1.00 46.55 ? 98 PHE A CE1 1 ATOM 593 C CE2 . PHE A 1 125 ? -14.265 -5.525 14.329 1.00 42.87 ? 98 PHE A CE2 1 ATOM 594 C CZ . PHE A 1 125 ? -12.895 -5.451 14.494 1.00 44.24 ? 98 PHE A CZ 1 ATOM 595 N N . ASP A 1 126 ? -15.407 -8.793 20.185 1.00 36.97 ? 99 ASP A N 1 ATOM 596 C CA . ASP A 1 126 ? -15.922 -9.029 21.531 1.00 36.17 ? 99 ASP A CA 1 ATOM 597 C C . ASP A 1 126 ? -16.506 -7.711 22.077 1.00 35.57 ? 99 ASP A C 1 ATOM 598 O O . ASP A 1 126 ? -15.828 -6.691 22.076 1.00 36.07 ? 99 ASP A O 1 ATOM 599 C CB . ASP A 1 126 ? -14.741 -9.473 22.420 1.00 34.82 ? 99 ASP A CB 1 ATOM 600 C CG . ASP A 1 126 ? -15.134 -9.826 23.845 1.00 38.70 ? 99 ASP A CG 1 ATOM 601 O OD1 . ASP A 1 126 ? -16.342 -9.801 24.218 1.00 39.04 ? 99 ASP A OD1 1 ATOM 602 O OD2 . ASP A 1 126 ? -14.210 -10.188 24.617 1.00 39.08 ? 99 ASP A OD2 1 ATOM 603 N N . THR A 1 127 ? -17.758 -7.727 22.534 1.00 35.78 ? 100 THR A N 1 ATOM 604 C CA . THR A 1 127 ? -18.358 -6.539 23.160 1.00 35.22 ? 100 THR A CA 1 ATOM 605 C C . THR A 1 127 ? -18.104 -6.462 24.668 1.00 35.00 ? 100 THR A C 1 ATOM 606 O O . THR A 1 127 ? -18.288 -5.401 25.263 1.00 34.99 ? 100 THR A O 1 ATOM 607 C CB . THR A 1 127 ? -19.869 -6.510 22.960 1.00 34.64 ? 100 THR A CB 1 ATOM 608 O OG1 . THR A 1 127 ? -20.450 -7.622 23.662 1.00 34.36 ? 100 THR A OG1 1 ATOM 609 C CG2 . THR A 1 127 ? -20.212 -6.587 21.477 1.00 35.71 ? 100 THR A CG2 1 ATOM 610 N N . CYS A 1 128 ? -17.730 -7.583 25.280 1.00 34.87 ? 101 CYS A N 1 ATOM 611 C CA . CYS A 1 128 ? -17.686 -7.730 26.734 1.00 37.36 ? 101 CYS A CA 1 ATOM 612 C C . CYS A 1 128 ? -18.983 -7.277 27.375 1.00 37.73 ? 101 CYS A C 1 ATOM 613 O O . CYS A 1 128 ? -18.978 -6.814 28.505 1.00 36.95 ? 101 CYS A O 1 ATOM 614 C CB . CYS A 1 128 ? -16.483 -6.969 27.323 1.00 43.24 ? 101 CYS A CB 1 ATOM 615 S SG . CYS A 1 128 ? -15.002 -7.462 26.410 1.00 50.66 ? 101 CYS A SG 1 ATOM 616 N N . ASN A 1 129 ? -20.103 -7.446 26.668 1.00 37.66 ? 102 ASN A N 1 ATOM 617 C CA . ASN A 1 129 ? -21.407 -6.956 27.116 1.00 38.00 ? 102 ASN A CA 1 ATOM 618 C C . ASN A 1 129 ? -21.429 -5.470 27.453 1.00 37.08 ? 102 ASN A C 1 ATOM 619 O O . ASN A 1 129 ? -22.221 -5.064 28.293 1.00 37.31 ? 102 ASN A O 1 ATOM 620 C CB . ASN A 1 129 ? -21.889 -7.739 28.343 1.00 42.55 ? 102 ASN A CB 1 ATOM 621 C CG . ASN A 1 129 ? -22.690 -8.965 27.993 1.00 45.71 ? 102 ASN A CG 1 ATOM 622 O OD1 . ASN A 1 129 ? -23.416 -9.000 26.995 1.00 50.66 ? 102 ASN A OD1 1 ATOM 623 N ND2 . ASN A 1 129 ? -22.581 -9.989 28.842 1.00 48.86 ? 102 ASN A ND2 1 ATOM 624 N N . THR A 1 130 ? -20.587 -4.664 26.807 1.00 31.58 ? 103 THR A N 1 ATOM 625 C CA . THR A 1 130 ? -20.466 -3.251 27.143 1.00 33.60 ? 103 THR A CA 1 ATOM 626 C C . THR A 1 130 ? -20.647 -2.378 25.916 1.00 32.05 ? 103 THR A C 1 ATOM 627 O O . THR A 1 130 ? -20.174 -2.717 24.817 1.00 31.64 ? 103 THR A O 1 ATOM 628 C CB . THR A 1 130 ? -19.113 -2.844 27.790 1.00 35.22 ? 103 THR A CB 1 ATOM 629 O OG1 . THR A 1 130 ? -18.093 -2.732 26.784 1.00 40.73 ? 103 THR A OG1 1 ATOM 630 C CG2 . THR A 1 130 ? -18.679 -3.811 28.807 1.00 34.17 ? 103 THR A CG2 1 ATOM 631 N N . VAL A 1 131 ? -21.306 -1.239 26.121 1.00 27.35 ? 104 VAL A N 1 ATOM 632 C CA . VAL A 1 131 ? -21.511 -0.283 25.054 1.00 28.18 ? 104 VAL A CA 1 ATOM 633 C C . VAL A 1 131 ? -20.175 0.212 24.463 1.00 28.91 ? 104 VAL A C 1 ATOM 634 O O . VAL A 1 131 ? -20.049 0.300 23.263 1.00 28.78 ? 104 VAL A O 1 ATOM 635 C CB . VAL A 1 131 ? -22.385 0.911 25.505 1.00 26.37 ? 104 VAL A CB 1 ATOM 636 C CG1 . VAL A 1 131 ? -22.354 2.057 24.498 1.00 25.80 ? 104 VAL A CG1 1 ATOM 637 C CG2 . VAL A 1 131 ? -23.828 0.462 25.667 1.00 27.78 ? 104 VAL A CG2 1 ATOM 638 N N . SER A 1 132 ? -19.214 0.569 25.299 1.00 28.72 ? 105 SER A N 1 ATOM 639 C CA . SER A 1 132 ? -17.999 1.234 24.807 1.00 29.84 ? 105 SER A CA 1 ATOM 640 C C . SER A 1 132 ? -17.198 0.300 23.897 1.00 31.18 ? 105 SER A C 1 ATOM 641 O O . SER A 1 132 ? -16.769 0.711 22.825 1.00 33.07 ? 105 SER A O 1 ATOM 642 C CB . SER A 1 132 ? -17.122 1.702 25.973 1.00 31.43 ? 105 SER A CB 1 ATOM 643 O OG . SER A 1 132 ? -16.720 0.587 26.755 1.00 33.14 ? 105 SER A OG 1 ATOM 644 N N . LYS A 1 133 ? -17.033 -0.953 24.296 1.00 31.47 ? 106 LYS A N 1 ATOM 645 C CA . LYS A 1 133 ? -16.322 -1.920 23.452 1.00 35.97 ? 106 LYS A CA 1 ATOM 646 C C . LYS A 1 133 ? -17.085 -2.170 22.151 1.00 36.31 ? 106 LYS A C 1 ATOM 647 O O . LYS A 1 133 ? -16.485 -2.203 21.068 1.00 31.13 ? 106 LYS A O 1 ATOM 648 C CB . LYS A 1 133 ? -16.122 -3.253 24.171 1.00 37.52 ? 106 LYS A CB 1 ATOM 649 C CG . LYS A 1 133 ? -15.339 -3.208 25.469 1.00 40.87 ? 106 LYS A CG 1 ATOM 650 C CD . LYS A 1 133 ? -13.871 -2.982 25.239 1.00 45.18 ? 106 LYS A CD 1 ATOM 651 C CE . LYS A 1 133 ? -13.158 -2.870 26.585 1.00 50.02 ? 106 LYS A CE 1 ATOM 652 N NZ . LYS A 1 133 ? -11.682 -2.758 26.422 1.00 52.31 ? 106 LYS A NZ 1 ATOM 653 N N . ALA A 1 134 ? -18.408 -2.335 22.246 1.00 35.04 ? 107 ALA A N 1 ATOM 654 C CA . ALA A 1 134 ? -19.225 -2.519 21.037 1.00 33.95 ? 107 ALA A CA 1 ATOM 655 C C . ALA A 1 134 ? -19.055 -1.356 20.082 1.00 34.35 ? 107 ALA A C 1 ATOM 656 O O . ALA A 1 134 ? -18.993 -1.538 18.866 1.00 32.50 ? 107 ALA A O 1 ATOM 657 C CB . ALA A 1 134 ? -20.689 -2.702 21.382 1.00 33.00 ? 107 ALA A CB 1 ATOM 658 N N . LEU A 1 135 ? -18.988 -0.150 20.629 1.00 34.80 ? 108 LEU A N 1 ATOM 659 C CA . LEU A 1 135 ? -18.890 1.050 19.788 1.00 36.82 ? 108 LEU A CA 1 ATOM 660 C C . LEU A 1 135 ? -17.531 1.261 19.139 1.00 33.90 ? 108 LEU A C 1 ATOM 661 O O . LEU A 1 135 ? -17.468 1.796 18.045 1.00 33.75 ? 108 LEU A O 1 ATOM 662 C CB . LEU A 1 135 ? -19.254 2.315 20.555 1.00 37.54 ? 108 LEU A CB 1 ATOM 663 C CG . LEU A 1 135 ? -20.565 3.012 20.228 1.00 42.93 ? 108 LEU A CG 1 ATOM 664 C CD1 . LEU A 1 135 ? -21.634 2.109 19.641 1.00 41.30 ? 108 LEU A CD1 1 ATOM 665 C CD2 . LEU A 1 135 ? -21.069 3.724 21.475 1.00 44.83 ? 108 LEU A CD2 1 ATOM 666 N N . GLU A 1 136 ? -16.464 0.925 19.843 1.00 35.21 ? 109 GLU A N 1 ATOM 667 C CA . GLU A 1 136 ? -15.114 0.922 19.254 1.00 39.14 ? 109 GLU A CA 1 ATOM 668 C C . GLU A 1 136 ? -15.129 0.003 18.042 1.00 35.64 ? 109 GLU A C 1 ATOM 669 O O . GLU A 1 136 ? -14.681 0.378 16.961 1.00 36.33 ? 109 GLU A O 1 ATOM 670 C CB . GLU A 1 136 ? -14.062 0.415 20.244 1.00 39.90 ? 109 GLU A CB 1 ATOM 671 C CG . GLU A 1 136 ? -13.797 1.349 21.414 1.00 46.35 ? 109 GLU A CG 1 ATOM 672 C CD . GLU A 1 136 ? -12.890 0.757 22.497 1.00 51.07 ? 109 GLU A CD 1 ATOM 673 O OE1 . GLU A 1 136 ? -12.320 -0.335 22.323 1.00 60.16 ? 109 GLU A OE1 1 ATOM 674 O OE2 . GLU A 1 136 ? -12.739 1.394 23.550 1.00 61.98 ? 109 GLU A OE2 1 ATOM 675 N N . ALA A 1 137 ? -15.685 -1.183 18.221 1.00 36.41 ? 110 ALA A N 1 ATOM 676 C CA . ALA A 1 137 ? -15.825 -2.139 17.109 1.00 37.57 ? 110 ALA A CA 1 ATOM 677 C C . ALA A 1 137 ? -16.631 -1.555 15.963 1.00 39.37 ? 110 ALA A C 1 ATOM 678 O O . ALA A 1 137 ? -16.243 -1.644 14.801 1.00 39.88 ? 110 ALA A O 1 ATOM 679 C CB . ALA A 1 137 ? -16.474 -3.419 17.594 1.00 38.21 ? 110 ALA A CB 1 ATOM 680 N N . THR A 1 138 ? -17.755 -0.942 16.298 1.00 36.91 ? 111 THR A N 1 ATOM 681 C CA . THR A 1 138 ? -18.650 -0.412 15.288 1.00 35.39 ? 111 THR A CA 1 ATOM 682 C C . THR A 1 138 ? -18.009 0.731 14.495 1.00 36.81 ? 111 THR A C 1 ATOM 683 O O . THR A 1 138 ? -18.273 0.880 13.302 1.00 37.52 ? 111 THR A O 1 ATOM 684 C CB . THR A 1 138 ? -19.990 0.011 15.929 1.00 33.65 ? 111 THR A CB 1 ATOM 685 O OG1 . THR A 1 138 ? -20.567 -1.137 16.580 1.00 32.87 ? 111 THR A OG1 1 ATOM 686 C CG2 . THR A 1 138 ? -20.956 0.543 14.895 1.00 33.73 ? 111 THR A CG2 1 ATOM 687 N N . LEU A 1 139 ? -17.183 1.542 15.145 1.00 35.04 ? 112 LEU A N 1 ATOM 688 C CA . LEU A 1 139 ? -16.448 2.579 14.429 1.00 38.01 ? 112 LEU A CA 1 ATOM 689 C C . LEU A 1 139 ? -15.522 1.966 13.355 1.00 37.96 ? 112 LEU A C 1 ATOM 690 O O . LEU A 1 139 ? -15.358 2.549 12.290 1.00 37.93 ? 112 LEU A O 1 ATOM 691 C CB . LEU A 1 139 ? -15.658 3.461 15.389 1.00 38.47 ? 112 LEU A CB 1 ATOM 692 C CG . LEU A 1 139 ? -16.489 4.406 16.261 1.00 39.54 ? 112 LEU A CG 1 ATOM 693 C CD1 . LEU A 1 139 ? -15.620 4.976 17.374 1.00 39.60 ? 112 LEU A CD1 1 ATOM 694 C CD2 . LEU A 1 139 ? -17.089 5.530 15.449 1.00 39.84 ? 112 LEU A CD2 1 ATOM 695 N N . SER A 1 140 ? -14.957 0.793 13.615 1.00 38.37 ? 113 SER A N 1 ATOM 696 C CA . SER A 1 140 ? -14.234 0.063 12.556 1.00 40.58 ? 113 SER A CA 1 ATOM 697 C C . SER A 1 140 ? -15.151 -0.373 11.427 1.00 42.81 ? 113 SER A C 1 ATOM 698 O O . SER A 1 140 ? -14.782 -0.250 10.266 1.00 44.39 ? 113 SER A O 1 ATOM 699 C CB . SER A 1 140 ? -13.577 -1.210 13.076 1.00 42.02 ? 113 SER A CB 1 ATOM 700 O OG . SER A 1 140 ? -12.871 -0.933 14.251 1.00 53.00 ? 113 SER A OG 1 ATOM 701 N N . PHE A 1 141 ? -16.332 -0.900 11.755 1.00 41.49 ? 114 PHE A N 1 ATOM 702 C CA . PHE A 1 141 ? -17.264 -1.319 10.709 1.00 38.72 ? 114 PHE A CA 1 ATOM 703 C C . PHE A 1 141 ? -17.654 -0.188 9.772 1.00 41.83 ? 114 PHE A C 1 ATOM 704 O O . PHE A 1 141 ? -17.917 -0.435 8.609 1.00 41.57 ? 114 PHE A O 1 ATOM 705 C CB . PHE A 1 141 ? -18.584 -1.867 11.267 1.00 38.88 ? 114 PHE A CB 1 ATOM 706 C CG . PHE A 1 141 ? -18.448 -3.098 12.105 1.00 39.02 ? 114 PHE A CG 1 ATOM 707 C CD1 . PHE A 1 141 ? -17.484 -4.046 11.841 1.00 39.89 ? 114 PHE A CD1 1 ATOM 708 C CD2 . PHE A 1 141 ? -19.324 -3.318 13.151 1.00 39.65 ? 114 PHE A CD2 1 ATOM 709 C CE1 . PHE A 1 141 ? -17.376 -5.175 12.623 1.00 39.90 ? 114 PHE A CE1 1 ATOM 710 C CE2 . PHE A 1 141 ? -19.230 -4.454 13.932 1.00 39.35 ? 114 PHE A CE2 1 ATOM 711 C CZ . PHE A 1 141 ? -18.250 -5.385 13.670 1.00 38.66 ? 114 PHE A CZ 1 ATOM 712 N N . VAL A 1 142 ? -17.748 1.038 10.272 1.00 41.17 ? 115 VAL A N 1 ATOM 713 C CA . VAL A 1 142 ? -18.196 2.141 9.438 1.00 40.14 ? 115 VAL A CA 1 ATOM 714 C C . VAL A 1 142 ? -17.040 3.028 8.962 1.00 45.05 ? 115 VAL A C 1 ATOM 715 O O . VAL A 1 142 ? -17.277 4.118 8.444 1.00 47.72 ? 115 VAL A O 1 ATOM 716 C CB . VAL A 1 142 ? -19.245 3.018 10.163 1.00 40.58 ? 115 VAL A CB 1 ATOM 717 C CG1 . VAL A 1 142 ? -20.420 2.165 10.626 1.00 41.22 ? 115 VAL A CG1 1 ATOM 718 C CG2 . VAL A 1 142 ? -18.629 3.769 11.342 1.00 40.07 ? 115 VAL A CG2 1 ATOM 719 N N . ALA A 1 143 ? -15.801 2.586 9.154 1.00 46.27 ? 116 ALA A N 1 ATOM 720 C CA . ALA A 1 143 ? -14.632 3.435 8.893 1.00 51.09 ? 116 ALA A CA 1 ATOM 721 C C . ALA A 1 143 ? -14.671 4.092 7.513 1.00 55.71 ? 116 ALA A C 1 ATOM 722 O O . ALA A 1 143 ? -14.453 5.296 7.403 1.00 55.54 ? 116 ALA A O 1 ATOM 723 C CB . ALA A 1 143 ? -13.351 2.632 9.056 1.00 51.96 ? 116 ALA A CB 1 ATOM 724 N N . GLN A 1 144 ? -14.970 3.306 6.476 1.00 59.28 ? 117 GLN A N 1 ATOM 725 C CA . GLN A 1 144 ? -15.067 3.831 5.107 1.00 66.84 ? 117 GLN A CA 1 ATOM 726 C C . GLN A 1 144 ? -16.187 4.871 4.974 1.00 69.90 ? 117 GLN A C 1 ATOM 727 O O . GLN A 1 144 ? -15.941 6.027 4.623 1.00 73.06 ? 117 GLN A O 1 ATOM 728 C CB . GLN A 1 144 ? -15.302 2.686 4.107 1.00 69.66 ? 117 GLN A CB 1 ATOM 729 C CG . GLN A 1 144 ? -15.189 3.073 2.631 1.00 73.39 ? 117 GLN A CG 1 ATOM 730 C CD . GLN A 1 144 ? -14.067 4.064 2.316 1.00 72.23 ? 117 GLN A CD 1 ATOM 731 O OE1 . GLN A 1 144 ? -14.299 5.232 1.963 1.00 69.28 ? 117 GLN A OE1 1 ATOM 732 N NE2 . GLN A 1 144 ? -12.844 3.587 2.429 1.00 70.24 ? 117 GLN A NE2 1 ATOM 733 N N . ASN A 1 145 ? -17.411 4.437 5.272 1.00 67.33 ? 118 ASN A N 1 ATOM 734 C CA . ASN A 1 145 ? -18.608 5.288 5.239 1.00 66.18 ? 118 ASN A CA 1 ATOM 735 C C . ASN A 1 145 ? -18.402 6.627 5.940 1.00 70.59 ? 118 ASN A C 1 ATOM 736 O O . ASN A 1 145 ? -18.844 7.661 5.441 1.00 72.98 ? 118 ASN A O 1 ATOM 737 C CB . ASN A 1 145 ? -19.808 4.605 5.922 1.00 60.66 ? 118 ASN A CB 1 ATOM 738 C CG . ASN A 1 145 ? -20.066 3.195 5.423 1.00 55.44 ? 118 ASN A CG 1 ATOM 739 O OD1 . ASN A 1 145 ? -20.942 2.975 4.592 1.00 55.75 ? 118 ASN A OD1 1 ATOM 740 N ND2 . ASN A 1 145 ? -19.329 2.230 5.957 1.00 54.38 ? 118 ASN A ND2 1 ATOM 741 N N . LYS A 1 146 ? -17.764 6.586 7.112 1.00 75.58 ? 119 LYS A N 1 ATOM 742 C CA . LYS A 1 146 ? -17.560 7.776 7.954 1.00 79.55 ? 119 LYS A CA 1 ATOM 743 C C . LYS A 1 146 ? -16.680 8.813 7.274 1.00 79.80 ? 119 LYS A C 1 ATOM 744 O O . LYS A 1 146 ? -16.985 10.010 7.313 1.00 77.31 ? 119 LYS A O 1 ATOM 745 C CB . LYS A 1 146 ? -16.940 7.394 9.302 1.00 80.31 ? 119 LYS A CB 1 ATOM 746 C CG . LYS A 1 146 ? -16.844 8.561 10.270 1.00 85.19 ? 119 LYS A CG 1 ATOM 747 C CD . LYS A 1 146 ? -15.688 8.419 11.240 1.00 90.10 ? 119 LYS A CD 1 ATOM 748 C CE . LYS A 1 146 ? -15.208 9.775 11.744 1.00 97.31 ? 119 LYS A CE 1 ATOM 749 N NZ . LYS A 1 146 ? -14.004 10.269 11.024 1.00 103.69 ? 119 LYS A NZ 1 ATOM 750 N N . ILE A 1 147 ? -15.585 8.341 6.674 1.00 83.42 ? 120 ILE A N 1 ATOM 751 C CA . ILE A 1 147 ? -14.693 9.180 5.867 1.00 88.70 ? 120 ILE A CA 1 ATOM 752 C C . ILE A 1 147 ? -15.476 9.914 4.754 1.00 90.04 ? 120 ILE A C 1 ATOM 753 O O . ILE A 1 147 ? -15.252 11.105 4.507 1.00 91.42 ? 120 ILE A O 1 ATOM 754 C CB . ILE A 1 147 ? -13.525 8.340 5.286 1.00 89.61 ? 120 ILE A CB 1 ATOM 755 C CG1 . ILE A 1 147 ? -12.596 7.869 6.409 1.00 87.60 ? 120 ILE A CG1 1 ATOM 756 C CG2 . ILE A 1 147 ? -12.703 9.139 4.285 1.00 92.06 ? 120 ILE A CG2 1 ATOM 757 C CD1 . ILE A 1 147 ? -11.793 6.638 6.045 1.00 88.86 ? 120 ILE A CD1 1 ATOM 758 N N . ASP A 1 148 ? -16.406 9.208 4.110 1.00 89.30 ? 121 ASP A N 1 ATOM 759 C CA . ASP A 1 148 ? -17.249 9.798 3.063 1.00 89.15 ? 121 ASP A CA 1 ATOM 760 C C . ASP A 1 148 ? -18.226 10.842 3.615 1.00 88.26 ? 121 ASP A C 1 ATOM 761 O O . ASP A 1 148 ? -18.399 11.899 3.013 1.00 91.37 ? 121 ASP A O 1 ATOM 762 C CB . ASP A 1 148 ? -18.036 8.712 2.315 1.00 86.90 ? 121 ASP A CB 1 ATOM 763 C CG . ASP A 1 148 ? -17.139 7.697 1.626 1.00 85.42 ? 121 ASP A CG 1 ATOM 764 O OD1 . ASP A 1 148 ? -15.902 7.871 1.626 1.00 78.42 ? 121 ASP A OD1 1 ATOM 765 O OD2 . ASP A 1 148 ? -17.682 6.710 1.088 1.00 89.43 ? 121 ASP A OD2 1 ATOM 766 N N . SER A 1 149 ? -18.863 10.541 4.746 1.00 84.14 ? 122 SER A N 1 ATOM 767 C CA . SER A 1 149 ? -19.823 11.462 5.365 1.00 88.10 ? 122 SER A CA 1 ATOM 768 C C . SER A 1 149 ? -19.220 12.838 5.714 1.00 89.30 ? 122 SER A C 1 ATOM 769 O O . SER A 1 149 ? -19.905 13.857 5.583 1.00 87.99 ? 122 SER A O 1 ATOM 770 C CB . SER A 1 149 ? -20.446 10.837 6.622 1.00 82.12 ? 122 SER A CB 1 ATOM 771 N N . LEU A 1 150 ? -17.954 12.865 6.143 1.00 89.47 ? 123 LEU A N 1 ATOM 772 C CA . LEU A 1 150 ? -17.302 14.106 6.597 1.00 93.39 ? 123 LEU A CA 1 ATOM 773 C C . LEU A 1 150 ? -16.362 14.768 5.578 1.00 95.31 ? 123 LEU A C 1 ATOM 774 O O . LEU A 1 150 ? -15.802 15.832 5.865 1.00 92.63 ? 123 LEU A O 1 ATOM 775 C CB . LEU A 1 150 ? -16.498 13.836 7.870 1.00 97.13 ? 123 LEU A CB 1 ATOM 776 C CG . LEU A 1 150 ? -17.241 13.160 9.020 1.00 97.41 ? 123 LEU A CG 1 ATOM 777 C CD1 . LEU A 1 150 ? -16.242 12.787 10.106 1.00 96.95 ? 123 LEU A CD1 1 ATOM 778 C CD2 . LEU A 1 150 ? -18.345 14.063 9.560 1.00 96.90 ? 123 LEU A CD2 1 ATOM 779 N N . ASN A 1 151 ? -16.191 14.151 4.405 1.00 96.42 ? 124 ASN A N 1 ATOM 780 C CA . ASN A 1 151 ? -15.181 14.587 3.420 1.00 94.47 ? 124 ASN A CA 1 ATOM 781 C C . ASN A 1 151 ? -13.760 14.491 3.992 1.00 95.07 ? 124 ASN A C 1 ATOM 782 O O . ASN A 1 151 ? -12.867 15.255 3.608 1.00 100.73 ? 124 ASN A O 1 ATOM 783 C CB . ASN A 1 151 ? -15.470 16.013 2.919 1.00 80.98 ? 124 ASN A CB 1 ATOM 784 N N . LEU A 1 152 ? -13.562 13.527 4.892 1.00 93.28 ? 125 LEU A N 1 ATOM 785 C CA . LEU A 1 152 ? -12.307 13.383 5.632 1.00 97.90 ? 125 LEU A CA 1 ATOM 786 C C . LEU A 1 152 ? -11.166 12.818 4.773 1.00 106.49 ? 125 LEU A C 1 ATOM 787 O O . LEU A 1 152 ? -9.991 12.919 5.155 1.00 108.65 ? 125 LEU A O 1 ATOM 788 C CB . LEU A 1 152 ? -12.509 12.466 6.845 1.00 95.91 ? 125 LEU A CB 1 ATOM 789 C CG . LEU A 1 152 ? -12.043 12.936 8.224 1.00 92.39 ? 125 LEU A CG 1 ATOM 790 C CD1 . LEU A 1 152 ? -11.857 11.701 9.090 1.00 92.27 ? 125 LEU A CD1 1 ATOM 791 C CD2 . LEU A 1 152 ? -10.771 13.777 8.206 1.00 89.55 ? 125 LEU A CD2 1 ATOM 792 N N . ASP A 1 153 ? -11.518 12.204 3.636 1.00 109.36 ? 126 ASP A N 1 ATOM 793 C CA . ASP A 1 153 ? -10.535 11.633 2.701 1.00 107.43 ? 126 ASP A CA 1 ATOM 794 C C . ASP A 1 153 ? -9.611 12.692 2.096 1.00 109.02 ? 126 ASP A C 1 ATOM 795 O O . ASP A 1 153 ? -8.475 12.389 1.727 1.00 108.91 ? 126 ASP A O 1 ATOM 796 C CB . ASP A 1 153 ? -11.248 10.890 1.567 1.00 98.04 ? 126 ASP A CB 1 ATOM 797 N N . GLU A 1 154 ? -10.103 13.927 1.989 1.00 108.97 ? 127 GLU A N 1 ATOM 798 C CA . GLU A 1 154 ? -9.315 15.021 1.427 1.00 109.95 ? 127 GLU A CA 1 ATOM 799 C C . GLU A 1 154 ? -8.488 15.798 2.471 1.00 112.27 ? 127 GLU A C 1 ATOM 800 O O . GLU A 1 154 ? -7.384 16.250 2.162 1.00 123.01 ? 127 GLU A O 1 ATOM 801 C CB . GLU A 1 154 ? -10.222 15.982 0.652 1.00 107.42 ? 127 GLU A CB 1 ATOM 802 C CG . GLU A 1 154 ? -10.741 17.160 1.461 1.00 106.56 ? 127 GLU A CG 1 ATOM 803 C CD . GLU A 1 154 ? -11.727 17.997 0.684 1.00 105.48 ? 127 GLU A CD 1 ATOM 804 O OE1 . GLU A 1 154 ? -12.592 17.409 0.000 1.00 99.78 ? 127 GLU A OE1 1 ATOM 805 O OE2 . GLU A 1 154 ? -11.635 19.242 0.760 1.00 105.17 ? 127 GLU A OE2 1 ATOM 806 N N . PHE A 1 155 ? -9.011 15.962 3.689 1.00 107.22 ? 128 PHE A N 1 ATOM 807 C CA . PHE A 1 155 ? -8.406 16.877 4.674 1.00 101.75 ? 128 PHE A CA 1 ATOM 808 C C . PHE A 1 155 ? -7.395 16.237 5.648 1.00 98.62 ? 128 PHE A C 1 ATOM 809 O O . PHE A 1 155 ? -6.781 16.942 6.454 1.00 100.12 ? 128 PHE A O 1 ATOM 810 C CB . PHE A 1 155 ? -9.510 17.601 5.457 1.00 97.72 ? 128 PHE A CB 1 ATOM 811 N N . CYS A 1 156 ? -7.226 14.917 5.575 1.00 97.13 ? 129 CYS A N 1 ATOM 812 C CA . CYS A 1 156 ? -6.195 14.198 6.340 1.00 93.41 ? 129 CYS A CA 1 ATOM 813 C C . CYS A 1 156 ? -5.686 13.038 5.494 1.00 93.48 ? 129 CYS A C 1 ATOM 814 O O . CYS A 1 156 ? -6.299 12.700 4.478 1.00 95.37 ? 129 CYS A O 1 ATOM 815 C CB . CYS A 1 156 ? -6.765 13.674 7.661 1.00 94.32 ? 129 CYS A CB 1 ATOM 816 N N . ASN A 1 157 ? -4.569 12.433 5.898 1.00 95.16 ? 130 ASN A N 1 ATOM 817 C CA . ASN A 1 157 ? -4.009 11.283 5.173 1.00 96.50 ? 130 ASN A CA 1 ATOM 818 C C . ASN A 1 157 ? -4.843 10.020 5.432 1.00 97.24 ? 130 ASN A C 1 ATOM 819 O O . ASN A 1 157 ? -4.874 9.520 6.559 1.00 100.20 ? 130 ASN A O 1 ATOM 820 C CB . ASN A 1 157 ? -2.547 11.048 5.576 1.00 90.82 ? 130 ASN A CB 1 ATOM 821 N N . CYS A 1 158 ? -5.514 9.515 4.393 1.00 96.15 ? 131 CYS A N 1 ATOM 822 C CA . CYS A 1 158 ? -6.463 8.400 4.538 1.00 97.91 ? 131 CYS A CA 1 ATOM 823 C C . CYS A 1 158 ? -6.274 7.311 3.466 1.00 99.68 ? 131 CYS A C 1 ATOM 824 O O . CYS A 1 158 ? -6.198 7.609 2.272 1.00 100.21 ? 131 CYS A O 1 ATOM 825 C CB . CYS A 1 158 ? -7.905 8.931 4.502 1.00 97.81 ? 131 CYS A CB 1 ATOM 826 S SG . CYS A 1 158 ? -8.450 9.765 6.017 1.00 98.16 ? 131 CYS A SG 1 ATOM 827 N N . SER A 1 159 ? -6.231 6.050 3.905 1.00 98.48 ? 132 SER A N 1 ATOM 828 C CA . SER A 1 159 ? -6.003 4.896 3.018 1.00 96.35 ? 132 SER A CA 1 ATOM 829 C C . SER A 1 159 ? -7.109 4.696 1.976 1.00 96.51 ? 132 SER A C 1 ATOM 830 O O . SER A 1 159 ? -8.210 5.227 2.109 1.00 99.82 ? 132 SER A O 1 ATOM 831 C CB . SER A 1 159 ? -5.846 3.610 3.842 1.00 93.93 ? 132 SER A CB 1 ATOM 832 O OG . SER A 1 159 ? -4.964 3.806 4.935 1.00 92.58 ? 132 SER A OG 1 ATOM 833 N N . GLU A 1 160 ? -6.794 3.939 0.928 1.00 96.06 ? 133 GLU A N 1 ATOM 834 C CA . GLU A 1 160 ? -7.772 3.588 -0.104 1.00 95.17 ? 133 GLU A CA 1 ATOM 835 C C . GLU A 1 160 ? -8.163 2.106 -0.027 1.00 96.16 ? 133 GLU A C 1 ATOM 836 O O . GLU A 1 160 ? -8.943 1.627 -0.852 1.00 92.33 ? 133 GLU A O 1 ATOM 837 C CB . GLU A 1 160 ? -7.227 3.921 -1.498 1.00 90.57 ? 133 GLU A CB 1 ATOM 838 N N . HIS A 1 161 ? -7.638 1.393 0.971 1.00 99.97 ? 134 HIS A N 1 ATOM 839 C CA . HIS A 1 161 ? -7.913 -0.036 1.138 1.00 104.06 ? 134 HIS A CA 1 ATOM 840 C C . HIS A 1 161 ? -8.698 -0.350 2.424 1.00 104.37 ? 134 HIS A C 1 ATOM 841 O O . HIS A 1 161 ? -8.414 -1.341 3.105 1.00 99.32 ? 134 HIS A O 1 ATOM 842 C CB . HIS A 1 161 ? -6.596 -0.818 1.112 1.00 106.50 ? 134 HIS A CB 1 ATOM 843 C CG . HIS A 1 161 ? -5.905 -0.779 -0.214 1.00 109.90 ? 134 HIS A CG 1 ATOM 844 N ND1 . HIS A 1 161 ? -5.349 0.372 -0.729 1.00 109.98 ? 134 HIS A ND1 1 ATOM 845 C CD2 . HIS A 1 161 ? -5.688 -1.747 -1.136 1.00 109.97 ? 134 HIS A CD2 1 ATOM 846 C CE1 . HIS A 1 161 ? -4.816 0.112 -1.909 1.00 109.42 ? 134 HIS A CE1 1 ATOM 847 N NE2 . HIS A 1 161 ? -5.008 -1.167 -2.179 1.00 111.15 ? 134 HIS A NE2 1 ATOM 848 N N . ILE A 1 162 ? -9.689 0.484 2.746 1.00 102.08 ? 135 ILE A N 1 ATOM 849 C CA . ILE A 1 162 ? -10.578 0.223 3.887 1.00 100.78 ? 135 ILE A CA 1 ATOM 850 C C . ILE A 1 162 ? -11.766 -0.624 3.401 1.00 97.44 ? 135 ILE A C 1 ATOM 851 O O . ILE A 1 162 ? -12.615 -0.131 2.654 1.00 93.28 ? 135 ILE A O 1 ATOM 852 C CB . ILE A 1 162 ? -11.086 1.527 4.555 1.00 98.45 ? 135 ILE A CB 1 ATOM 853 C CG1 . ILE A 1 162 ? -9.914 2.422 4.987 1.00 95.57 ? 135 ILE A CG1 1 ATOM 854 C CG2 . ILE A 1 162 ? -11.979 1.211 5.751 1.00 96.28 ? 135 ILE A CG2 1 ATOM 855 C CD1 . ILE A 1 162 ? -9.644 3.575 4.052 1.00 93.79 ? 135 ILE A CD1 1 ATOM 856 N N . PRO A 1 163 ? -11.835 -1.902 3.828 1.00 99.92 ? 136 PRO A N 1 ATOM 857 C CA . PRO A 1 163 ? -12.871 -2.791 3.303 1.00 95.69 ? 136 PRO A CA 1 ATOM 858 C C . PRO A 1 163 ? -14.226 -2.503 3.944 1.00 85.26 ? 136 PRO A C 1 ATOM 859 O O . PRO A 1 163 ? -14.300 -2.211 5.144 1.00 74.15 ? 136 PRO A O 1 ATOM 860 C CB . PRO A 1 163 ? -12.365 -4.179 3.693 1.00 98.80 ? 136 PRO A CB 1 ATOM 861 C CG . PRO A 1 163 ? -11.612 -3.948 4.967 1.00 102.48 ? 136 PRO A CG 1 ATOM 862 C CD . PRO A 1 163 ? -11.105 -2.524 4.951 1.00 101.65 ? 136 PRO A CD 1 ATOM 863 N N . SER A 1 164 ? -15.281 -2.592 3.142 1.00 74.08 ? 137 SER A N 1 ATOM 864 C CA . SER A 1 164 ? -16.595 -2.190 3.570 1.00 67.71 ? 137 SER A CA 1 ATOM 865 C C . SER A 1 164 ? -17.311 -3.333 4.275 1.00 66.51 ? 137 SER A C 1 ATOM 866 O O . SER A 1 164 ? -17.262 -4.488 3.833 1.00 68.92 ? 137 SER A O 1 ATOM 867 C CB . SER A 1 164 ? -17.423 -1.710 2.383 1.00 64.96 ? 137 SER A CB 1 ATOM 868 O OG . SER A 1 164 ? -16.979 -0.428 1.981 1.00 69.81 ? 137 SER A OG 1 ATOM 869 N N . THR A 1 165 ? -17.970 -2.998 5.378 1.00 61.85 ? 138 THR A N 1 ATOM 870 C CA . THR A 1 165 ? -18.845 -3.931 6.074 1.00 54.01 ? 138 THR A CA 1 ATOM 871 C C . THR A 1 165 ? -20.229 -3.746 5.485 1.00 47.03 ? 138 THR A C 1 ATOM 872 O O . THR A 1 165 ? -20.727 -2.644 5.417 1.00 46.39 ? 138 THR A O 1 ATOM 873 C CB . THR A 1 165 ? -18.865 -3.648 7.575 1.00 55.35 ? 138 THR A CB 1 ATOM 874 O OG1 . THR A 1 165 ? -17.519 -3.583 8.060 1.00 58.53 ? 138 THR A OG1 1 ATOM 875 C CG2 . THR A 1 165 ? -19.602 -4.748 8.313 1.00 59.15 ? 138 THR A CG2 1 ATOM 876 N N . ILE A 1 166 ? -20.848 -4.830 5.055 1.00 42.88 ? 139 ILE A N 1 ATOM 877 C CA . ILE A 1 166 ? -22.128 -4.755 4.358 1.00 43.04 ? 139 ILE A CA 1 ATOM 878 C C . ILE A 1 166 ? -23.322 -5.048 5.263 1.00 37.34 ? 139 ILE A C 1 ATOM 879 O O . ILE A 1 166 ? -24.439 -4.687 4.932 1.00 35.97 ? 139 ILE A O 1 ATOM 880 C CB . ILE A 1 166 ? -22.145 -5.716 3.138 1.00 44.78 ? 139 ILE A CB 1 ATOM 881 C CG1 . ILE A 1 166 ? -22.792 -5.031 1.944 1.00 47.31 ? 139 ILE A CG1 1 ATOM 882 C CG2 . ILE A 1 166 ? -22.826 -7.037 3.442 1.00 46.64 ? 139 ILE A CG2 1 ATOM 883 C CD1 . ILE A 1 166 ? -21.881 -3.958 1.369 1.00 50.41 ? 139 ILE A CD1 1 ATOM 884 N N . ALA A 1 167 ? -23.070 -5.731 6.377 1.00 36.21 ? 140 ALA A N 1 ATOM 885 C CA . ALA A 1 167 ? -24.101 -6.034 7.369 1.00 35.80 ? 140 ALA A CA 1 ATOM 886 C C . ALA A 1 167 ? -23.430 -6.475 8.656 1.00 33.87 ? 140 ALA A C 1 ATOM 887 O O . ALA A 1 167 ? -22.275 -6.921 8.638 1.00 35.26 ? 140 ALA A O 1 ATOM 888 C CB . ALA A 1 167 ? -25.032 -7.115 6.851 1.00 36.95 ? 140 ALA A CB 1 ATOM 889 N N . VAL A 1 168 ? -24.143 -6.364 9.775 1.00 32.25 ? 141 VAL A N 1 ATOM 890 C CA . VAL A 1 168 ? -23.583 -6.709 11.082 1.00 30.89 ? 141 VAL A CA 1 ATOM 891 C C . VAL A 1 168 ? -24.541 -7.640 11.777 1.00 33.00 ? 141 VAL A C 1 ATOM 892 O O . VAL A 1 168 ? -25.756 -7.417 11.763 1.00 36.47 ? 141 VAL A O 1 ATOM 893 C CB . VAL A 1 168 ? -23.316 -5.456 11.937 1.00 32.35 ? 141 VAL A CB 1 ATOM 894 C CG1 . VAL A 1 168 ? -22.887 -5.805 13.365 1.00 32.09 ? 141 VAL A CG1 1 ATOM 895 C CG2 . VAL A 1 168 ? -22.248 -4.599 11.271 1.00 33.48 ? 141 VAL A CG2 1 ATOM 896 N N . VAL A 1 169 ? -23.978 -8.681 12.373 1.00 32.57 ? 142 VAL A N 1 ATOM 897 C CA . VAL A 1 169 ? -24.701 -9.631 13.188 1.00 33.35 ? 142 VAL A CA 1 ATOM 898 C C . VAL A 1 169 ? -24.429 -9.318 14.662 1.00 32.53 ? 142 VAL A C 1 ATOM 899 O O . VAL A 1 169 ? -23.285 -9.370 15.109 1.00 31.37 ? 142 VAL A O 1 ATOM 900 C CB . VAL A 1 169 ? -24.253 -11.066 12.867 1.00 35.70 ? 142 VAL A CB 1 ATOM 901 C CG1 . VAL A 1 169 ? -24.889 -12.076 13.825 1.00 33.71 ? 142 VAL A CG1 1 ATOM 902 C CG2 . VAL A 1 169 ? -24.626 -11.421 11.424 1.00 37.13 ? 142 VAL A CG2 1 ATOM 903 N N . GLY A 1 170 ? -25.486 -8.992 15.407 1.00 31.97 ? 143 GLY A N 1 ATOM 904 C CA . GLY A 1 170 ? -25.353 -8.619 16.809 1.00 29.37 ? 143 GLY A CA 1 ATOM 905 C C . GLY A 1 170 ? -26.200 -7.399 17.142 1.00 28.46 ? 143 GLY A C 1 ATOM 906 O O . GLY A 1 170 ? -26.964 -6.905 16.297 1.00 27.10 ? 143 GLY A O 1 ATOM 907 N N . ALA A 1 171 ? -26.101 -6.911 18.369 1.00 25.80 ? 144 ALA A N 1 ATOM 908 C CA . ALA A 1 171 ? -25.330 -7.508 19.454 1.00 26.06 ? 144 ALA A CA 1 ATOM 909 C C . ALA A 1 171 ? -26.255 -8.333 20.350 1.00 27.40 ? 144 ALA A C 1 ATOM 910 O O . ALA A 1 171 ? -27.391 -8.632 19.965 1.00 27.69 ? 144 ALA A O 1 ATOM 911 C CB . ALA A 1 171 ? -24.666 -6.382 20.236 1.00 26.44 ? 144 ALA A CB 1 ATOM 912 N N . THR A 1 172 ? -25.812 -8.656 21.562 1.00 27.71 ? 145 THR A N 1 ATOM 913 C CA . THR A 1 172 ? -26.650 -9.425 22.494 1.00 31.13 ? 145 THR A CA 1 ATOM 914 C C . THR A 1 172 ? -27.571 -8.568 23.355 1.00 29.67 ? 145 THR A C 1 ATOM 915 O O . THR A 1 172 ? -28.802 -8.605 23.177 1.00 27.63 ? 145 THR A O 1 ATOM 916 C CB . THR A 1 172 ? -25.798 -10.325 23.390 1.00 32.37 ? 145 THR A CB 1 ATOM 917 O OG1 . THR A 1 172 ? -25.122 -11.256 22.553 1.00 34.41 ? 145 THR A OG1 1 ATOM 918 C CG2 . THR A 1 172 ? -26.662 -11.111 24.392 1.00 32.41 ? 145 THR A CG2 1 ATOM 919 N N . GLY A 1 173 ? -26.988 -7.797 24.276 1.00 29.36 ? 146 GLY A N 1 ATOM 920 C CA . GLY A 1 173 ? -27.784 -6.938 25.158 1.00 28.62 ? 146 GLY A CA 1 ATOM 921 C C . GLY A 1 173 ? -28.479 -5.834 24.362 1.00 28.96 ? 146 GLY A C 1 ATOM 922 O O . GLY A 1 173 ? -27.869 -5.199 23.501 1.00 28.16 ? 146 GLY A O 1 ATOM 923 N N . SER A 1 174 ? -29.751 -5.572 24.657 1.00 28.50 ? 147 SER A N 1 ATOM 924 C CA . SER A 1 174 ? -30.480 -4.513 23.934 1.00 27.53 ? 147 SER A CA 1 ATOM 925 C C . SER A 1 174 ? -29.846 -3.145 24.084 1.00 27.01 ? 147 SER A C 1 ATOM 926 O O . SER A 1 174 ? -29.929 -2.333 23.171 1.00 26.67 ? 147 SER A O 1 ATOM 927 C CB . SER A 1 174 ? -31.948 -4.453 24.345 1.00 28.25 ? 147 SER A CB 1 ATOM 928 O OG . SER A 1 174 ? -32.666 -5.537 23.784 1.00 27.44 ? 147 SER A OG 1 ATOM 929 N N . GLY A 1 175 ? -29.242 -2.877 25.247 1.00 27.25 ? 148 GLY A N 1 ATOM 930 C CA . GLY A 1 175 ? -28.547 -1.602 25.497 1.00 26.08 ? 148 GLY A CA 1 ATOM 931 C C . GLY A 1 175 ? -27.356 -1.415 24.590 1.00 24.81 ? 148 GLY A C 1 ATOM 932 O O . GLY A 1 175 ? -27.099 -0.326 24.092 1.00 28.18 ? 148 GLY A O 1 ATOM 933 N N . VAL A 1 176 ? -26.667 -2.508 24.311 1.00 24.12 ? 149 VAL A N 1 ATOM 934 C CA . VAL A 1 176 ? -25.557 -2.508 23.374 1.00 24.30 ? 149 VAL A CA 1 ATOM 935 C C . VAL A 1 176 ? -26.098 -2.366 21.954 1.00 25.64 ? 149 VAL A C 1 ATOM 936 O O . VAL A 1 176 ? -25.568 -1.577 21.180 1.00 25.59 ? 149 VAL A O 1 ATOM 937 C CB . VAL A 1 176 ? -24.698 -3.791 23.557 1.00 25.15 ? 149 VAL A CB 1 ATOM 938 C CG1 . VAL A 1 176 ? -23.579 -3.888 22.533 1.00 25.24 ? 149 VAL A CG1 1 ATOM 939 C CG2 . VAL A 1 176 ? -24.101 -3.814 24.961 1.00 25.23 ? 149 VAL A CG2 1 ATOM 940 N N . SER A 1 177 ? -27.131 -3.138 21.595 1.00 25.21 ? 150 SER A N 1 ATOM 941 C CA . SER A 1 177 ? -27.648 -3.103 20.217 1.00 26.39 ? 150 SER A CA 1 ATOM 942 C C . SER A 1 177 ? -28.228 -1.745 19.873 1.00 27.71 ? 150 SER A C 1 ATOM 943 O O . SER A 1 177 ? -28.067 -1.296 18.733 1.00 29.33 ? 150 SER A O 1 ATOM 944 C CB . SER A 1 177 ? -28.704 -4.196 19.929 1.00 27.08 ? 150 SER A CB 1 ATOM 945 O OG . SER A 1 177 ? -28.112 -5.489 19.793 1.00 23.62 ? 150 SER A OG 1 ATOM 946 N N . THR A 1 178 ? -28.896 -1.090 20.836 1.00 26.60 ? 151 THR A N 1 ATOM 947 C CA . THR A 1 178 ? -29.417 0.267 20.603 1.00 25.97 ? 151 THR A CA 1 ATOM 948 C C . THR A 1 178 ? -28.307 1.269 20.253 1.00 24.02 ? 151 THR A C 1 ATOM 949 O O . THR A 1 178 ? -28.412 2.008 19.301 1.00 25.60 ? 151 THR A O 1 ATOM 950 C CB . THR A 1 178 ? -30.300 0.838 21.755 1.00 25.36 ? 151 THR A CB 1 ATOM 951 O OG1 . THR A 1 178 ? -29.633 0.735 22.992 1.00 31.13 ? 151 THR A OG1 1 ATOM 952 C CG2 . THR A 1 178 ? -31.572 0.063 21.855 1.00 28.98 ? 151 THR A CG2 1 ATOM 953 N N . ALA A 1 179 ? -27.227 1.268 21.009 1.00 25.13 ? 152 ALA A N 1 ATOM 954 C CA . ALA A 1 179 ? -26.133 2.174 20.751 1.00 25.83 ? 152 ALA A CA 1 ATOM 955 C C . ALA A 1 179 ? -25.444 1.854 19.411 1.00 27.20 ? 152 ALA A C 1 ATOM 956 O O . ALA A 1 179 ? -25.070 2.741 18.671 1.00 28.61 ? 152 ALA A O 1 ATOM 957 C CB . ALA A 1 179 ? -25.116 2.101 21.883 1.00 26.49 ? 152 ALA A CB 1 ATOM 958 N N . VAL A 1 180 ? -25.223 0.584 19.134 1.00 27.81 ? 153 VAL A N 1 ATOM 959 C CA . VAL A 1 180 ? -24.689 0.182 17.825 1.00 27.32 ? 153 VAL A CA 1 ATOM 960 C C . VAL A 1 180 ? -25.642 0.631 16.700 1.00 28.37 ? 153 VAL A C 1 ATOM 961 O O . VAL A 1 180 ? -25.200 1.179 15.697 1.00 27.81 ? 153 VAL A O 1 ATOM 962 C CB . VAL A 1 180 ? -24.454 -1.338 17.774 1.00 27.98 ? 153 VAL A CB 1 ATOM 963 C CG1 . VAL A 1 180 ? -24.107 -1.805 16.374 1.00 30.79 ? 153 VAL A CG1 1 ATOM 964 C CG2 . VAL A 1 180 ? -23.337 -1.722 18.723 1.00 29.11 ? 153 VAL A CG2 1 ATOM 965 N N . ALA A 1 181 ? -26.945 0.418 16.880 1.00 28.48 ? 154 ALA A N 1 ATOM 966 C CA . ALA A 1 181 ? -27.924 0.751 15.840 1.00 29.79 ? 154 ALA A CA 1 ATOM 967 C C . ALA A 1 181 ? -27.992 2.226 15.500 1.00 31.23 ? 154 ALA A C 1 ATOM 968 O O . ALA A 1 181 ? -28.256 2.587 14.353 1.00 29.48 ? 154 ALA A O 1 ATOM 969 C CB . ALA A 1 181 ? -29.303 0.243 16.224 1.00 29.22 ? 154 ALA A CB 1 ATOM 970 N N . ASN A 1 182 ? -27.775 3.094 16.486 1.00 30.32 ? 155 ASN A N 1 ATOM 971 C CA . ASN A 1 182 ? -27.769 4.521 16.209 1.00 29.93 ? 155 ASN A CA 1 ATOM 972 C C . ASN A 1 182 ? -26.685 4.848 15.178 1.00 31.22 ? 155 ASN A C 1 ATOM 973 O O . ASN A 1 182 ? -26.852 5.748 14.358 1.00 30.90 ? 155 ASN A O 1 ATOM 974 C CB . ASN A 1 182 ? -27.477 5.340 17.474 1.00 30.89 ? 155 ASN A CB 1 ATOM 975 C CG . ASN A 1 182 ? -28.655 5.397 18.441 1.00 30.99 ? 155 ASN A CG 1 ATOM 976 O OD1 . ASN A 1 182 ? -29.816 5.420 18.045 1.00 29.77 ? 155 ASN A OD1 1 ATOM 977 N ND2 . ASN A 1 182 ? -28.342 5.425 19.714 1.00 33.49 ? 155 ASN A ND2 1 ATOM 978 N N . LEU A 1 183 ? -25.556 4.162 15.289 1.00 30.55 ? 156 LEU A N 1 ATOM 979 C CA . LEU A 1 183 ? -24.421 4.432 14.428 1.00 33.74 ? 156 LEU A CA 1 ATOM 980 C C . LEU A 1 183 ? -24.556 3.742 13.059 1.00 32.79 ? 156 LEU A C 1 ATOM 981 O O . LEU A 1 183 ? -24.378 4.368 12.025 1.00 31.32 ? 156 LEU A O 1 ATOM 982 C CB . LEU A 1 183 ? -23.153 3.975 15.122 1.00 33.89 ? 156 LEU A CB 1 ATOM 983 C CG . LEU A 1 183 ? -21.856 4.493 14.547 1.00 38.97 ? 156 LEU A CG 1 ATOM 984 C CD1 . LEU A 1 183 ? -21.920 5.955 14.142 1.00 40.34 ? 156 LEU A CD1 1 ATOM 985 C CD2 . LEU A 1 183 ? -20.730 4.236 15.541 1.00 39.55 ? 156 LEU A CD2 1 ATOM 986 N N . LEU A 1 184 ? -24.871 2.457 13.068 1.00 31.64 ? 157 LEU A N 1 ATOM 987 C CA . LEU A 1 184 ? -25.059 1.730 11.818 1.00 31.39 ? 157 LEU A CA 1 ATOM 988 C C . LEU A 1 184 ? -26.203 2.296 10.998 1.00 31.03 ? 157 LEU A C 1 ATOM 989 O O . LEU A 1 184 ? -26.082 2.415 9.783 1.00 32.19 ? 157 LEU A O 1 ATOM 990 C CB . LEU A 1 184 ? -25.284 0.266 12.073 1.00 29.86 ? 157 LEU A CB 1 ATOM 991 C CG . LEU A 1 184 ? -24.079 -0.460 12.650 1.00 31.37 ? 157 LEU A CG 1 ATOM 992 C CD1 . LEU A 1 184 ? -24.472 -1.891 12.919 1.00 30.35 ? 157 LEU A CD1 1 ATOM 993 C CD2 . LEU A 1 184 ? -22.849 -0.434 11.733 1.00 32.18 ? 157 LEU A CD2 1 ATOM 994 N N . GLY A 1 185 ? -27.284 2.699 11.661 1.00 31.07 ? 158 GLY A N 1 ATOM 995 C CA . GLY A 1 185 ? -28.439 3.319 10.985 1.00 31.92 ? 158 GLY A CA 1 ATOM 996 C C . GLY A 1 185 ? -28.115 4.607 10.225 1.00 35.40 ? 158 GLY A C 1 ATOM 997 O O . GLY A 1 185 ? -28.773 4.937 9.232 1.00 33.70 ? 158 GLY A O 1 ATOM 998 N N . LEU A 1 186 ? -27.117 5.346 10.698 1.00 36.34 ? 159 LEU A N 1 ATOM 999 C CA . LEU A 1 186 ? -26.647 6.525 9.985 1.00 39.38 ? 159 LEU A CA 1 ATOM 1000 C C . LEU A 1 186 ? -26.226 6.215 8.584 1.00 35.72 ? 159 LEU A C 1 ATOM 1001 O O . LEU A 1 186 ? -26.437 7.035 7.703 1.00 39.22 ? 159 LEU A O 1 ATOM 1002 C CB . LEU A 1 186 ? -25.411 7.141 10.643 1.00 42.56 ? 159 LEU A CB 1 ATOM 1003 C CG . LEU A 1 186 ? -25.630 8.103 11.777 1.00 45.40 ? 159 LEU A CG 1 ATOM 1004 C CD1 . LEU A 1 186 ? -24.262 8.623 12.217 1.00 45.76 ? 159 LEU A CD1 1 ATOM 1005 C CD2 . LEU A 1 186 ? -26.521 9.239 11.299 1.00 49.35 ? 159 LEU A CD2 1 ATOM 1006 N N . PHE A 1 187 ? -25.588 5.062 8.398 1.00 34.95 ? 160 PHE A N 1 ATOM 1007 C CA . PHE A 1 187 ? -25.064 4.663 7.094 1.00 38.12 ? 160 PHE A CA 1 ATOM 1008 C C . PHE A 1 187 ? -25.912 3.602 6.417 1.00 36.49 ? 160 PHE A C 1 ATOM 1009 O O . PHE A 1 187 ? -25.513 3.030 5.408 1.00 37.25 ? 160 PHE A O 1 ATOM 1010 C CB . PHE A 1 187 ? -23.648 4.170 7.286 1.00 38.60 ? 160 PHE A CB 1 ATOM 1011 C CG . PHE A 1 187 ? -22.793 5.159 8.010 1.00 40.96 ? 160 PHE A CG 1 ATOM 1012 C CD1 . PHE A 1 187 ? -22.469 6.371 7.408 1.00 43.10 ? 160 PHE A CD1 1 ATOM 1013 C CD2 . PHE A 1 187 ? -22.360 4.914 9.302 1.00 38.18 ? 160 PHE A CD2 1 ATOM 1014 C CE1 . PHE A 1 187 ? -21.699 7.308 8.078 1.00 44.54 ? 160 PHE A CE1 1 ATOM 1015 C CE2 . PHE A 1 187 ? -21.591 5.837 9.968 1.00 41.09 ? 160 PHE A CE2 1 ATOM 1016 C CZ . PHE A 1 187 ? -21.257 7.036 9.364 1.00 42.50 ? 160 PHE A CZ 1 ATOM 1017 N N . TYR A 1 188 ? -27.099 3.366 6.962 1.00 35.48 ? 161 TYR A N 1 ATOM 1018 C CA . TYR A 1 188 ? -28.011 2.374 6.442 1.00 36.17 ? 161 TYR A CA 1 ATOM 1019 C C . TYR A 1 188 ? -27.352 1.027 6.280 1.00 36.97 ? 161 TYR A C 1 ATOM 1020 O O . TYR A 1 188 ? -27.620 0.308 5.318 1.00 38.28 ? 161 TYR A O 1 ATOM 1021 C CB . TYR A 1 188 ? -28.616 2.849 5.120 1.00 37.93 ? 161 TYR A CB 1 ATOM 1022 C CG . TYR A 1 188 ? -29.546 3.989 5.308 1.00 35.66 ? 161 TYR A CG 1 ATOM 1023 C CD1 . TYR A 1 188 ? -29.080 5.298 5.347 1.00 37.49 ? 161 TYR A CD1 1 ATOM 1024 C CD2 . TYR A 1 188 ? -30.887 3.760 5.499 1.00 38.20 ? 161 TYR A CD2 1 ATOM 1025 C CE1 . TYR A 1 188 ? -29.946 6.356 5.554 1.00 39.29 ? 161 TYR A CE1 1 ATOM 1026 C CE2 . TYR A 1 188 ? -31.759 4.798 5.699 1.00 41.67 ? 161 TYR A CE2 1 ATOM 1027 C CZ . TYR A 1 188 ? -31.289 6.091 5.726 1.00 39.72 ? 161 TYR A CZ 1 ATOM 1028 O OH . TYR A 1 188 ? -32.202 7.091 5.920 1.00 45.89 ? 161 TYR A OH 1 ATOM 1029 N N . ILE A 1 189 ? -26.500 0.679 7.241 1.00 34.89 ? 162 ILE A N 1 ATOM 1030 C CA . ILE A 1 189 ? -25.914 -0.637 7.284 1.00 33.65 ? 162 ILE A CA 1 ATOM 1031 C C . ILE A 1 189 ? -26.830 -1.559 8.082 1.00 34.34 ? 162 ILE A C 1 ATOM 1032 O O . ILE A 1 189 ? -27.132 -1.275 9.241 1.00 32.36 ? 162 ILE A O 1 ATOM 1033 C CB . ILE A 1 189 ? -24.521 -0.601 7.921 1.00 34.97 ? 162 ILE A CB 1 ATOM 1034 C CG1 . ILE A 1 189 ? -23.580 0.194 7.009 1.00 35.53 ? 162 ILE A CG1 1 ATOM 1035 C CG2 . ILE A 1 189 ? -23.997 -2.012 8.130 1.00 32.99 ? 162 ILE A CG2 1 ATOM 1036 C CD1 . ILE A 1 189 ? -22.286 0.601 7.670 1.00 38.36 ? 162 ILE A CD1 1 ATOM 1037 N N . PRO A 1 190 ? -27.273 -2.662 7.471 1.00 34.13 ? 163 PRO A N 1 ATOM 1038 C CA . PRO A 1 190 ? -28.207 -3.532 8.170 1.00 33.22 ? 163 PRO A CA 1 ATOM 1039 C C . PRO A 1 190 ? -27.551 -4.228 9.321 1.00 31.67 ? 163 PRO A C 1 ATOM 1040 O O . PRO A 1 190 ? -26.362 -4.584 9.252 1.00 33.02 ? 163 PRO A O 1 ATOM 1041 C CB . PRO A 1 190 ? -28.643 -4.533 7.106 1.00 34.48 ? 163 PRO A CB 1 ATOM 1042 C CG . PRO A 1 190 ? -27.571 -4.490 6.080 1.00 35.72 ? 163 PRO A CG 1 ATOM 1043 C CD . PRO A 1 190 ? -27.056 -3.091 6.078 1.00 36.31 ? 163 PRO A CD 1 ATOM 1044 N N . GLN A 1 191 ? -28.333 -4.373 10.391 1.00 28.94 ? 164 GLN A N 1 ATOM 1045 C CA . GLN A 1 191 ? -27.909 -4.998 11.618 1.00 28.20 ? 164 GLN A CA 1 ATOM 1046 C C . GLN A 1 191 ? -28.972 -6.013 11.978 1.00 28.24 ? 164 GLN A C 1 ATOM 1047 O O . GLN A 1 191 ? -30.147 -5.664 12.083 1.00 29.94 ? 164 GLN A O 1 ATOM 1048 C CB . GLN A 1 191 ? -27.780 -3.940 12.729 1.00 27.25 ? 164 GLN A CB 1 ATOM 1049 C CG . GLN A 1 191 ? -27.323 -4.475 14.075 1.00 27.86 ? 164 GLN A CG 1 ATOM 1050 C CD . GLN A 1 191 ? -27.397 -3.443 15.186 1.00 27.49 ? 164 GLN A CD 1 ATOM 1051 O OE1 . GLN A 1 191 ? -27.585 -2.258 14.941 1.00 27.30 ? 164 GLN A OE1 1 ATOM 1052 N NE2 . GLN A 1 191 ? -27.266 -3.902 16.425 1.00 29.20 ? 164 GLN A NE2 1 ATOM 1053 N N . VAL A 1 192 ? -28.562 -7.265 12.165 1.00 29.61 ? 165 VAL A N 1 ATOM 1054 C CA . VAL A 1 192 ? -29.489 -8.336 12.497 1.00 31.19 ? 165 VAL A CA 1 ATOM 1055 C C . VAL A 1 192 ? -29.058 -8.902 13.829 1.00 31.05 ? 165 VAL A C 1 ATOM 1056 O O . VAL A 1 192 ? -28.018 -9.544 13.935 1.00 32.86 ? 165 VAL A O 1 ATOM 1057 C CB . VAL A 1 192 ? -29.510 -9.468 11.443 1.00 32.71 ? 165 VAL A CB 1 ATOM 1058 C CG1 . VAL A 1 192 ? -30.603 -10.473 11.756 1.00 35.96 ? 165 VAL A CG1 1 ATOM 1059 C CG2 . VAL A 1 192 ? -29.718 -8.899 10.059 1.00 33.15 ? 165 VAL A CG2 1 ATOM 1060 N N . SER A 1 193 ? -29.860 -8.667 14.861 1.00 29.63 ? 166 SER A N 1 ATOM 1061 C CA . SER A 1 193 ? -29.502 -9.156 16.170 1.00 28.44 ? 166 SER A CA 1 ATOM 1062 C C . SER A 1 193 ? -30.093 -10.521 16.384 1.00 30.34 ? 166 SER A C 1 ATOM 1063 O O . SER A 1 193 ? -31.249 -10.790 16.014 1.00 29.60 ? 166 SER A O 1 ATOM 1064 C CB . SER A 1 193 ? -29.984 -8.220 17.275 1.00 28.89 ? 166 SER A CB 1 ATOM 1065 O OG . SER A 1 193 ? -29.638 -8.777 18.544 1.00 27.04 ? 166 SER A OG 1 ATOM 1066 N N . TYR A 1 194 ? -29.291 -11.354 17.029 1.00 29.77 ? 167 TYR A N 1 ATOM 1067 C CA . TYR A 1 194 ? -29.668 -12.716 17.379 1.00 31.39 ? 167 TYR A CA 1 ATOM 1068 C C . TYR A 1 194 ? -30.269 -12.803 18.803 1.00 30.56 ? 167 TYR A C 1 ATOM 1069 O O . TYR A 1 194 ? -30.826 -13.836 19.169 1.00 29.59 ? 167 TYR A O 1 ATOM 1070 C CB . TYR A 1 194 ? -28.437 -13.638 17.247 1.00 29.94 ? 167 TYR A CB 1 ATOM 1071 C CG . TYR A 1 194 ? -27.218 -13.082 17.967 1.00 30.15 ? 167 TYR A CG 1 ATOM 1072 C CD1 . TYR A 1 194 ? -27.063 -13.248 19.332 1.00 30.71 ? 167 TYR A CD1 1 ATOM 1073 C CD2 . TYR A 1 194 ? -26.230 -12.378 17.272 1.00 28.34 ? 167 TYR A CD2 1 ATOM 1074 C CE1 . TYR A 1 194 ? -25.962 -12.735 19.994 1.00 31.54 ? 167 TYR A CE1 1 ATOM 1075 C CE2 . TYR A 1 194 ? -25.132 -11.873 17.922 1.00 29.31 ? 167 TYR A CE2 1 ATOM 1076 C CZ . TYR A 1 194 ? -25.000 -12.039 19.279 1.00 31.31 ? 167 TYR A CZ 1 ATOM 1077 O OH . TYR A 1 194 ? -23.923 -11.506 19.936 1.00 30.87 ? 167 TYR A OH 1 ATOM 1078 N N . ALA A 1 195 ? -30.172 -11.733 19.607 1.00 28.38 ? 168 ALA A N 1 ATOM 1079 C CA . ALA A 1 195 ? -30.660 -11.808 20.982 1.00 28.77 ? 168 ALA A CA 1 ATOM 1080 C C . ALA A 1 195 ? -31.299 -10.547 21.615 1.00 29.56 ? 168 ALA A C 1 ATOM 1081 O O . ALA A 1 195 ? -31.852 -10.642 22.721 1.00 28.35 ? 168 ALA A O 1 ATOM 1082 C CB . ALA A 1 195 ? -29.529 -12.281 21.868 1.00 30.18 ? 168 ALA A CB 1 ATOM 1083 N N . SER A 1 196 ? -31.216 -9.398 20.963 1.00 26.88 ? 169 SER A N 1 ATOM 1084 C CA . SER A 1 196 ? -31.722 -8.157 21.548 1.00 27.02 ? 169 SER A CA 1 ATOM 1085 C C . SER A 1 196 ? -33.219 -8.098 21.351 1.00 25.51 ? 169 SER A C 1 ATOM 1086 O O . SER A 1 196 ? -33.695 -7.933 20.239 1.00 25.12 ? 169 SER A O 1 ATOM 1087 C CB . SER A 1 196 ? -31.053 -6.933 20.921 1.00 27.31 ? 169 SER A CB 1 ATOM 1088 O OG . SER A 1 196 ? -29.681 -6.897 21.235 1.00 26.77 ? 169 SER A OG 1 ATOM 1089 N N . SER A 1 197 ? -33.956 -8.260 22.443 1.00 25.64 ? 170 SER A N 1 ATOM 1090 C CA . SER A 1 197 ? -35.386 -8.438 22.374 1.00 27.46 ? 170 SER A CA 1 ATOM 1091 C C . SER A 1 197 ? -36.196 -7.223 22.792 1.00 27.03 ? 170 SER A C 1 ATOM 1092 O O . SER A 1 197 ? -37.430 -7.290 22.802 1.00 28.04 ? 170 SER A O 1 ATOM 1093 C CB . SER A 1 197 ? -35.806 -9.654 23.227 1.00 25.86 ? 170 SER A CB 1 ATOM 1094 O OG . SER A 1 197 ? -35.318 -9.555 24.539 1.00 25.68 ? 170 SER A OG 1 ATOM 1095 N N . SER A 1 198 ? -35.546 -6.118 23.136 1.00 26.81 ? 171 SER A N 1 ATOM 1096 C CA . SER A 1 198 ? -36.305 -4.936 23.595 1.00 25.80 ? 171 SER A CA 1 ATOM 1097 C C . SER A 1 198 ? -37.315 -4.426 22.564 1.00 26.41 ? 171 SER A C 1 ATOM 1098 O O . SER A 1 198 ? -36.992 -4.284 21.373 1.00 25.08 ? 171 SER A O 1 ATOM 1099 C CB . SER A 1 198 ? -35.352 -3.793 23.929 1.00 25.88 ? 171 SER A CB 1 ATOM 1100 O OG . SER A 1 198 ? -36.072 -2.630 24.300 1.00 25.29 ? 171 SER A OG 1 ATOM 1101 N N . ARG A 1 199 ? -38.521 -4.095 23.028 1.00 26.77 ? 172 ARG A N 1 ATOM 1102 C CA . ARG A 1 199 ? -39.550 -3.478 22.168 1.00 25.68 ? 172 ARG A CA 1 ATOM 1103 C C . ARG A 1 199 ? -39.107 -2.121 21.621 1.00 25.56 ? 172 ARG A C 1 ATOM 1104 O O . ARG A 1 199 ? -39.616 -1.662 20.613 1.00 25.72 ? 172 ARG A O 1 ATOM 1105 C CB . ARG A 1 199 ? -40.884 -3.360 22.909 1.00 28.00 ? 172 ARG A CB 1 ATOM 1106 C CG . ARG A 1 199 ? -40.879 -2.359 24.069 1.00 29.15 ? 172 ARG A CG 1 ATOM 1107 C CD . ARG A 1 199 ? -41.462 -1.062 23.597 1.00 30.15 ? 172 ARG A CD 1 ATOM 1108 N NE . ARG A 1 199 ? -41.593 -0.090 24.674 1.00 29.71 ? 172 ARG A NE 1 ATOM 1109 C CZ . ARG A 1 199 ? -41.746 1.218 24.488 1.00 28.45 ? 172 ARG A CZ 1 ATOM 1110 N NH1 . ARG A 1 199 ? -41.771 1.735 23.270 1.00 27.04 ? 172 ARG A NH1 1 ATOM 1111 N NH2 . ARG A 1 199 ? -41.868 2.019 25.538 1.00 28.49 ? 172 ARG A NH2 1 ATOM 1112 N N . LEU A 1 200 ? -38.151 -1.469 22.270 1.00 24.50 ? 173 LEU A N 1 ATOM 1113 C CA . LEU A 1 200 ? -37.665 -0.174 21.807 1.00 24.58 ? 173 LEU A CA 1 ATOM 1114 C C . LEU A 1 200 ? -37.028 -0.261 20.435 1.00 24.77 ? 173 LEU A C 1 ATOM 1115 O O . LEU A 1 200 ? -37.106 0.690 19.660 1.00 27.89 ? 173 LEU A O 1 ATOM 1116 C CB . LEU A 1 200 ? -36.614 0.393 22.774 1.00 25.66 ? 173 LEU A CB 1 ATOM 1117 C CG . LEU A 1 200 ? -37.085 0.664 24.204 1.00 28.78 ? 173 LEU A CG 1 ATOM 1118 C CD1 . LEU A 1 200 ? -35.896 1.137 25.036 1.00 30.68 ? 173 LEU A CD1 1 ATOM 1119 C CD2 . LEU A 1 200 ? -38.198 1.698 24.242 1.00 29.52 ? 173 LEU A CD2 1 ATOM 1120 N N . LEU A 1 201 ? -36.359 -1.381 20.159 1.00 26.65 ? 174 LEU A N 1 ATOM 1121 C CA . LEU A 1 201 ? -35.710 -1.600 18.872 1.00 26.76 ? 174 LEU A CA 1 ATOM 1122 C C . LEU A 1 201 ? -36.699 -1.816 17.715 1.00 28.36 ? 174 LEU A C 1 ATOM 1123 O O . LEU A 1 201 ? -36.269 -1.845 16.560 1.00 30.09 ? 174 LEU A O 1 ATOM 1124 C CB . LEU A 1 201 ? -34.725 -2.761 18.952 1.00 27.51 ? 174 LEU A CB 1 ATOM 1125 C CG . LEU A 1 201 ? -33.472 -2.453 19.765 1.00 28.41 ? 174 LEU A CG 1 ATOM 1126 C CD1 . LEU A 1 201 ? -32.826 -3.699 20.318 1.00 26.65 ? 174 LEU A CD1 1 ATOM 1127 C CD2 . LEU A 1 201 ? -32.464 -1.674 18.938 1.00 29.78 ? 174 LEU A CD2 1 ATOM 1128 N N . SER A 1 202 ? -37.993 -1.950 18.014 1.00 26.73 ? 175 SER A N 1 ATOM 1129 C CA . SER A 1 202 ? -39.055 -2.038 16.974 1.00 27.72 ? 175 SER A CA 1 ATOM 1130 C C . SER A 1 202 ? -39.387 -0.715 16.328 1.00 28.33 ? 175 SER A C 1 ATOM 1131 O O . SER A 1 202 ? -40.122 -0.668 15.344 1.00 31.06 ? 175 SER A O 1 ATOM 1132 C CB . SER A 1 202 ? -40.359 -2.603 17.573 1.00 26.59 ? 175 SER A CB 1 ATOM 1133 O OG . SER A 1 202 ? -40.181 -3.934 18.039 1.00 28.21 ? 175 SER A OG 1 ATOM 1134 N N . ASN A 1 203 ? -38.871 0.365 16.891 1.00 29.71 ? 176 ASN A N 1 ATOM 1135 C CA . ASN A 1 203 ? -39.081 1.692 16.370 1.00 29.35 ? 176 ASN A CA 1 ATOM 1136 C C . ASN A 1 203 ? -38.174 1.990 15.175 1.00 30.31 ? 176 ASN A C 1 ATOM 1137 O O . ASN A 1 203 ? -36.970 2.282 15.337 1.00 27.68 ? 176 ASN A O 1 ATOM 1138 C CB . ASN A 1 203 ? -38.795 2.683 17.487 1.00 31.57 ? 176 ASN A CB 1 ATOM 1139 C CG . ASN A 1 203 ? -39.000 4.115 17.055 1.00 33.98 ? 176 ASN A CG 1 ATOM 1140 O OD1 . ASN A 1 203 ? -39.132 4.413 15.875 1.00 34.40 ? 176 ASN A OD1 1 ATOM 1141 N ND2 . ASN A 1 203 ? -38.965 5.011 18.003 1.00 38.04 ? 176 ASN A ND2 1 ATOM 1142 N N . LYS A 1 204 ? -38.745 1.929 13.971 1.00 32.67 ? 177 LYS A N 1 ATOM 1143 C CA . LYS A 1 204 ? -37.964 2.111 12.734 1.00 33.94 ? 177 LYS A CA 1 ATOM 1144 C C . LYS A 1 204 ? -37.658 3.562 12.396 1.00 34.55 ? 177 LYS A C 1 ATOM 1145 O O . LYS A 1 204 ? -36.788 3.808 11.572 1.00 37.56 ? 177 LYS A O 1 ATOM 1146 C CB . LYS A 1 204 ? -38.614 1.411 11.521 1.00 34.63 ? 177 LYS A CB 1 ATOM 1147 C CG . LYS A 1 204 ? -38.770 -0.104 11.627 1.00 32.89 ? 177 LYS A CG 1 ATOM 1148 C CD . LYS A 1 204 ? -37.471 -0.866 11.901 1.00 33.54 ? 177 LYS A CD 1 ATOM 1149 C CE . LYS A 1 204 ? -37.166 -0.957 13.397 1.00 31.59 ? 177 LYS A CE 1 ATOM 1150 N NZ . LYS A 1 204 ? -36.346 -2.131 13.717 1.00 34.05 ? 177 LYS A NZ 1 ATOM 1151 N N . ASN A 1 205 ? -38.337 4.522 13.007 1.00 36.16 ? 178 ASN A N 1 ATOM 1152 C CA . ASN A 1 205 ? -37.896 5.915 12.910 1.00 37.64 ? 178 ASN A CA 1 ATOM 1153 C C . ASN A 1 205 ? -36.538 6.146 13.544 1.00 37.79 ? 178 ASN A C 1 ATOM 1154 O O . ASN A 1 205 ? -35.695 6.828 12.968 1.00 35.84 ? 178 ASN A O 1 ATOM 1155 C CB . ASN A 1 205 ? -38.878 6.865 13.568 1.00 42.39 ? 178 ASN A CB 1 ATOM 1156 C CG . ASN A 1 205 ? -40.181 6.942 12.816 1.00 45.87 ? 178 ASN A CG 1 ATOM 1157 O OD1 . ASN A 1 205 ? -40.196 6.868 11.589 1.00 52.40 ? 178 ASN A OD1 1 ATOM 1158 N ND2 . ASN A 1 205 ? -41.282 7.060 13.541 1.00 47.04 ? 178 ASN A ND2 1 ATOM 1159 N N . GLN A 1 206 ? -36.328 5.564 14.718 1.00 35.27 ? 179 GLN A N 1 ATOM 1160 C CA . GLN A 1 206 ? -35.054 5.673 15.379 1.00 32.92 ? 179 GLN A CA 1 ATOM 1161 C C . GLN A 1 206 ? -34.035 4.652 14.864 1.00 32.43 ? 179 GLN A C 1 ATOM 1162 O O . GLN A 1 206 ? -32.863 4.980 14.704 1.00 27.77 ? 179 GLN A O 1 ATOM 1163 C CB . GLN A 1 206 ? -35.205 5.559 16.894 1.00 34.90 ? 179 GLN A CB 1 ATOM 1164 C CG . GLN A 1 206 ? -33.843 5.571 17.563 1.00 42.66 ? 179 GLN A CG 1 ATOM 1165 C CD . GLN A 1 206 ? -33.691 6.491 18.755 1.00 50.87 ? 179 GLN A CD 1 ATOM 1166 O OE1 . GLN A 1 206 ? -32.868 6.224 19.651 1.00 54.62 ? 179 GLN A OE1 1 ATOM 1167 N NE2 . GLN A 1 206 ? -34.396 7.619 18.735 1.00 56.73 ? 179 GLN A NE2 1 ATOM 1168 N N . PHE A 1 207 ? -34.471 3.425 14.593 1.00 29.93 ? 180 PHE A N 1 ATOM 1169 C CA . PHE A 1 207 ? -33.543 2.366 14.261 1.00 28.66 ? 180 PHE A CA 1 ATOM 1170 C C . PHE A 1 207 ? -33.833 1.845 12.851 1.00 31.31 ? 180 PHE A C 1 ATOM 1171 O O . PHE A 1 207 ? -34.417 0.765 12.654 1.00 32.01 ? 180 PHE A O 1 ATOM 1172 C CB . PHE A 1 207 ? -33.609 1.259 15.306 1.00 27.69 ? 180 PHE A CB 1 ATOM 1173 C CG . PHE A 1 207 ? -33.381 1.737 16.712 1.00 27.22 ? 180 PHE A CG 1 ATOM 1174 C CD1 . PHE A 1 207 ? -32.137 2.170 17.110 1.00 26.65 ? 180 PHE A CD1 1 ATOM 1175 C CD2 . PHE A 1 207 ? -34.416 1.737 17.641 1.00 25.92 ? 180 PHE A CD2 1 ATOM 1176 C CE1 . PHE A 1 207 ? -31.912 2.604 18.413 1.00 28.09 ? 180 PHE A CE1 1 ATOM 1177 C CE2 . PHE A 1 207 ? -34.215 2.165 18.938 1.00 27.09 ? 180 PHE A CE2 1 ATOM 1178 C CZ . PHE A 1 207 ? -32.962 2.600 19.342 1.00 28.11 ? 180 PHE A CZ 1 ATOM 1179 N N . LYS A 1 208 ? -33.359 2.607 11.875 1.00 30.99 ? 181 LYS A N 1 ATOM 1180 C CA . LYS A 1 208 ? -33.723 2.403 10.489 1.00 36.45 ? 181 LYS A CA 1 ATOM 1181 C C . LYS A 1 208 ? -33.188 1.111 9.899 1.00 34.69 ? 181 LYS A C 1 ATOM 1182 O O . LYS A 1 208 ? -33.782 0.590 8.968 1.00 37.98 ? 181 LYS A O 1 ATOM 1183 C CB . LYS A 1 208 ? -33.236 3.568 9.631 1.00 40.62 ? 181 LYS A CB 1 ATOM 1184 C CG . LYS A 1 208 ? -33.937 4.871 9.919 1.00 46.86 ? 181 LYS A CG 1 ATOM 1185 C CD . LYS A 1 208 ? -33.162 6.003 9.281 1.00 51.70 ? 181 LYS A CD 1 ATOM 1186 C CE . LYS A 1 208 ? -33.874 7.324 9.485 1.00 58.27 ? 181 LYS A CE 1 ATOM 1187 N NZ . LYS A 1 208 ? -33.062 8.400 8.853 1.00 62.33 ? 181 LYS A NZ 1 ATOM 1188 N N . SER A 1 209 ? -32.059 0.632 10.397 1.00 29.59 ? 182 SER A N 1 ATOM 1189 C CA . SER A 1 209 ? -31.392 -0.498 9.769 1.00 31.17 ? 182 SER A CA 1 ATOM 1190 C C . SER A 1 209 ? -31.360 -1.748 10.628 1.00 31.47 ? 182 SER A C 1 ATOM 1191 O O . SER A 1 209 ? -30.624 -2.670 10.339 1.00 32.92 ? 182 SER A O 1 ATOM 1192 C CB . SER A 1 209 ? -29.973 -0.095 9.328 1.00 31.53 ? 182 SER A CB 1 ATOM 1193 O OG . SER A 1 209 ? -29.072 -0.063 10.416 1.00 31.66 ? 182 SER A OG 1 ATOM 1194 N N . PHE A 1 210 ? -32.206 -1.800 11.657 1.00 31.34 ? 183 PHE A N 1 ATOM 1195 C CA . PHE A 1 210 ? -32.176 -2.880 12.627 1.00 28.49 ? 183 PHE A CA 1 ATOM 1196 C C . PHE A 1 210 ? -33.265 -3.907 12.360 1.00 28.78 ? 183 PHE A C 1 ATOM 1197 O O . PHE A 1 210 ? -34.437 -3.551 12.167 1.00 27.64 ? 183 PHE A O 1 ATOM 1198 C CB . PHE A 1 210 ? -32.360 -2.334 14.041 1.00 27.61 ? 183 PHE A CB 1 ATOM 1199 C CG . PHE A 1 210 ? -32.299 -3.396 15.096 1.00 26.11 ? 183 PHE A CG 1 ATOM 1200 C CD1 . PHE A 1 210 ? -31.089 -3.786 15.643 1.00 26.14 ? 183 PHE A CD1 1 ATOM 1201 C CD2 . PHE A 1 210 ? -33.444 -4.015 15.520 1.00 27.16 ? 183 PHE A CD2 1 ATOM 1202 C CE1 . PHE A 1 210 ? -31.033 -4.789 16.586 1.00 26.67 ? 183 PHE A CE1 1 ATOM 1203 C CE2 . PHE A 1 210 ? -33.398 -5.007 16.486 1.00 27.73 ? 183 PHE A CE2 1 ATOM 1204 C CZ . PHE A 1 210 ? -32.196 -5.396 17.017 1.00 27.10 ? 183 PHE A CZ 1 ATOM 1205 N N . LEU A 1 211 ? -32.868 -5.178 12.435 1.00 27.57 ? 184 LEU A N 1 ATOM 1206 C CA . LEU A 1 211 ? -33.769 -6.306 12.373 1.00 29.54 ? 184 LEU A CA 1 ATOM 1207 C C . LEU A 1 211 ? -33.282 -7.355 13.325 1.00 28.96 ? 184 LEU A C 1 ATOM 1208 O O . LEU A 1 211 ? -32.187 -7.243 13.853 1.00 31.37 ? 184 LEU A O 1 ATOM 1209 C CB . LEU A 1 211 ? -33.747 -6.937 10.978 1.00 35.01 ? 184 LEU A CB 1 ATOM 1210 C CG . LEU A 1 211 ? -34.075 -5.959 9.861 1.00 37.20 ? 184 LEU A CG 1 ATOM 1211 C CD1 . LEU A 1 211 ? -32.804 -5.605 9.112 1.00 39.84 ? 184 LEU A CD1 1 ATOM 1212 C CD2 . LEU A 1 211 ? -35.118 -6.540 8.941 1.00 41.36 ? 184 LEU A CD2 1 ATOM 1213 N N . ARG A 1 212 ? -34.072 -8.400 13.539 1.00 28.17 ? 185 ARG A N 1 ATOM 1214 C CA . ARG A 1 212 ? -33.653 -9.414 14.477 1.00 29.42 ? 185 ARG A CA 1 ATOM 1215 C C . ARG A 1 212 ? -34.326 -10.752 14.262 1.00 30.60 ? 185 ARG A C 1 ATOM 1216 O O . ARG A 1 212 ? -35.471 -10.823 13.795 1.00 31.55 ? 185 ARG A O 1 ATOM 1217 C CB . ARG A 1 212 ? -33.902 -8.941 15.910 1.00 28.10 ? 185 ARG A CB 1 ATOM 1218 C CG . ARG A 1 212 ? -35.309 -8.443 16.156 1.00 28.20 ? 185 ARG A CG 1 ATOM 1219 C CD . ARG A 1 212 ? -35.486 -7.994 17.593 1.00 27.02 ? 185 ARG A CD 1 ATOM 1220 N NE . ARG A 1 212 ? -36.587 -7.043 17.715 1.00 28.49 ? 185 ARG A NE 1 ATOM 1221 C CZ . ARG A 1 212 ? -36.764 -6.222 18.748 1.00 27.74 ? 185 ARG A CZ 1 ATOM 1222 N NH1 . ARG A 1 212 ? -35.901 -6.210 19.770 1.00 27.09 ? 185 ARG A NH1 1 ATOM 1223 N NH2 . ARG A 1 212 ? -37.803 -5.396 18.754 1.00 27.46 ? 185 ARG A NH2 1 ATOM 1224 N N . THR A 1 213 ? -33.601 -11.800 14.653 1.00 29.85 ? 186 THR A N 1 ATOM 1225 C CA . THR A 1 213 ? -34.093 -13.161 14.557 1.00 32.61 ? 186 THR A CA 1 ATOM 1226 C C . THR A 1 213 ? -34.562 -13.689 15.905 1.00 32.75 ? 186 THR A C 1 ATOM 1227 O O . THR A 1 213 ? -34.757 -14.866 16.051 1.00 33.96 ? 186 THR A O 1 ATOM 1228 C CB . THR A 1 213 ? -33.020 -14.099 14.013 1.00 31.21 ? 186 THR A CB 1 ATOM 1229 O OG1 . THR A 1 213 ? -31.806 -13.917 14.746 1.00 30.16 ? 186 THR A OG1 1 ATOM 1230 C CG2 . THR A 1 213 ? -32.778 -13.799 12.568 1.00 32.56 ? 186 THR A CG2 1 ATOM 1231 N N . ILE A 1 214 ? -34.784 -12.801 16.864 1.00 31.23 ? 187 ILE A N 1 ATOM 1232 C CA . ILE A 1 214 ? -35.418 -13.160 18.116 1.00 31.52 ? 187 ILE A CA 1 ATOM 1233 C C . ILE A 1 214 ? -36.684 -12.335 18.252 1.00 32.09 ? 187 ILE A C 1 ATOM 1234 O O . ILE A 1 214 ? -36.705 -11.187 17.813 1.00 32.42 ? 187 ILE A O 1 ATOM 1235 C CB . ILE A 1 214 ? -34.480 -12.877 19.303 1.00 33.44 ? 187 ILE A CB 1 ATOM 1236 C CG1 . ILE A 1 214 ? -35.054 -13.482 20.579 1.00 31.88 ? 187 ILE A CG1 1 ATOM 1237 C CG2 . ILE A 1 214 ? -34.203 -11.371 19.462 1.00 32.24 ? 187 ILE A CG2 1 ATOM 1238 C CD1 . ILE A 1 214 ? -34.080 -13.519 21.734 1.00 31.77 ? 187 ILE A CD1 1 ATOM 1239 N N . PRO A 1 215 ? -37.749 -12.905 18.853 1.00 33.67 ? 188 PRO A N 1 ATOM 1240 C CA . PRO A 1 215 ? -38.926 -12.064 19.048 1.00 32.88 ? 188 PRO A CA 1 ATOM 1241 C C . PRO A 1 215 ? -38.697 -10.946 20.059 1.00 31.26 ? 188 PRO A C 1 ATOM 1242 O O . PRO A 1 215 ? -37.908 -11.079 20.981 1.00 31.20 ? 188 PRO A O 1 ATOM 1243 C CB . PRO A 1 215 ? -39.996 -13.045 19.558 1.00 34.66 ? 188 PRO A CB 1 ATOM 1244 C CG . PRO A 1 215 ? -39.454 -14.410 19.253 1.00 35.27 ? 188 PRO A CG 1 ATOM 1245 C CD . PRO A 1 215 ? -37.972 -14.281 19.345 1.00 32.83 ? 188 PRO A CD 1 ATOM 1246 N N . ASN A 1 216 ? -39.410 -9.855 19.885 1.00 32.13 ? 189 ASN A N 1 ATOM 1247 C CA . ASN A 1 216 ? -39.439 -8.838 20.909 1.00 34.64 ? 189 ASN A CA 1 ATOM 1248 C C . ASN A 1 216 ? -40.230 -9.309 22.134 1.00 33.51 ? 189 ASN A C 1 ATOM 1249 O O . ASN A 1 216 ? -40.976 -10.277 22.096 1.00 37.01 ? 189 ASN A O 1 ATOM 1250 C CB . ASN A 1 216 ? -39.896 -7.489 20.340 1.00 35.40 ? 189 ASN A CB 1 ATOM 1251 C CG . ASN A 1 216 ? -41.397 -7.300 20.355 1.00 36.71 ? 189 ASN A CG 1 ATOM 1252 O OD1 . ASN A 1 216 ? -42.075 -7.720 21.273 1.00 38.22 ? 189 ASN A OD1 1 ATOM 1253 N ND2 . ASN A 1 216 ? -41.914 -6.589 19.365 1.00 39.05 ? 189 ASN A ND2 1 ATOM 1254 N N . ASP A 1 217 ? -40.012 -8.618 23.234 1.00 36.03 ? 190 ASP A N 1 ATOM 1255 C CA . ASP A 1 217 ? -40.482 -9.057 24.551 1.00 34.68 ? 190 ASP A CA 1 ATOM 1256 C C . ASP A 1 217 ? -41.952 -8.744 24.888 1.00 33.44 ? 190 ASP A C 1 ATOM 1257 O O . ASP A 1 217 ? -42.396 -9.016 26.005 1.00 33.59 ? 190 ASP A O 1 ATOM 1258 C CB . ASP A 1 217 ? -39.566 -8.439 25.608 1.00 34.77 ? 190 ASP A CB 1 ATOM 1259 C CG . ASP A 1 217 ? -38.246 -9.187 25.747 1.00 37.38 ? 190 ASP A CG 1 ATOM 1260 O OD1 . ASP A 1 217 ? -38.269 -10.439 25.626 1.00 36.20 ? 190 ASP A OD1 1 ATOM 1261 O OD2 . ASP A 1 217 ? -37.194 -8.504 25.974 1.00 34.90 ? 190 ASP A OD2 1 ATOM 1262 N N . GLU A 1 218 ? -42.689 -8.131 23.975 1.00 33.46 ? 191 GLU A N 1 ATOM 1263 C CA . GLU A 1 218 ? -44.063 -7.751 24.275 1.00 32.78 ? 191 GLU A CA 1 ATOM 1264 C C . GLU A 1 218 ? -44.908 -8.976 24.694 1.00 35.20 ? 191 GLU A C 1 ATOM 1265 O O . GLU A 1 218 ? -45.636 -8.914 25.689 1.00 34.65 ? 191 GLU A O 1 ATOM 1266 C CB . GLU A 1 218 ? -44.692 -7.016 23.096 1.00 33.74 ? 191 GLU A CB 1 ATOM 1267 C CG . GLU A 1 218 ? -44.033 -5.658 22.802 1.00 34.51 ? 191 GLU A CG 1 ATOM 1268 C CD . GLU A 1 218 ? -44.560 -4.560 23.712 1.00 35.07 ? 191 GLU A CD 1 ATOM 1269 O OE1 . GLU A 1 218 ? -45.610 -4.006 23.352 1.00 36.66 ? 191 GLU A OE1 1 ATOM 1270 O OE2 . GLU A 1 218 ? -43.949 -4.246 24.775 1.00 32.28 ? 191 GLU A OE2 1 ATOM 1271 N N . HIS A 1 219 ? -44.773 -10.097 23.989 1.00 33.38 ? 192 HIS A N 1 ATOM 1272 C CA . HIS A 1 219 ? -45.556 -11.289 24.302 1.00 33.98 ? 192 HIS A CA 1 ATOM 1273 C C . HIS A 1 219 ? -45.051 -11.926 25.568 1.00 34.10 ? 192 HIS A C 1 ATOM 1274 O O . HIS A 1 219 ? -45.835 -12.454 26.358 1.00 37.39 ? 192 HIS A O 1 ATOM 1275 C CB . HIS A 1 219 ? -45.571 -12.324 23.163 1.00 35.29 ? 192 HIS A CB 1 ATOM 1276 C CG . HIS A 1 219 ? -46.607 -12.056 22.119 1.00 35.83 ? 192 HIS A CG 1 ATOM 1277 N ND1 . HIS A 1 219 ? -47.956 -12.034 22.400 1.00 38.87 ? 192 HIS A ND1 1 ATOM 1278 C CD2 . HIS A 1 219 ? -46.492 -11.823 20.789 1.00 36.63 ? 192 HIS A CD2 1 ATOM 1279 C CE1 . HIS A 1 219 ? -48.627 -11.772 21.288 1.00 39.42 ? 192 HIS A CE1 1 ATOM 1280 N NE2 . HIS A 1 219 ? -47.760 -11.642 20.300 1.00 36.82 ? 192 HIS A NE2 1 ATOM 1281 N N . GLN A 1 220 ? -43.748 -11.902 25.773 1.00 32.67 ? 193 GLN A N 1 ATOM 1282 C CA . GLN A 1 220 ? -43.187 -12.537 26.936 1.00 33.38 ? 193 GLN A CA 1 ATOM 1283 C C . GLN A 1 220 ? -43.651 -11.856 28.239 1.00 33.75 ? 193 GLN A C 1 ATOM 1284 O O . GLN A 1 220 ? -43.933 -12.522 29.238 1.00 31.35 ? 193 GLN A O 1 ATOM 1285 C CB . GLN A 1 220 ? -41.666 -12.523 26.852 1.00 36.19 ? 193 GLN A CB 1 ATOM 1286 C CG . GLN A 1 220 ? -41.059 -13.478 27.830 1.00 36.99 ? 193 GLN A CG 1 ATOM 1287 C CD . GLN A 1 220 ? -39.548 -13.434 27.845 1.00 39.01 ? 193 GLN A CD 1 ATOM 1288 O OE1 . GLN A 1 220 ? -38.884 -13.122 26.853 1.00 43.28 ? 193 GLN A OE1 1 ATOM 1289 N NE2 . GLN A 1 220 ? -39.005 -13.814 28.952 1.00 37.89 ? 193 GLN A NE2 1 ATOM 1290 N N . ALA A 1 221 ? -43.684 -10.531 28.238 1.00 29.45 ? 194 ALA A N 1 ATOM 1291 C CA . ALA A 1 221 ? -44.113 -9.788 29.406 1.00 29.28 ? 194 ALA A CA 1 ATOM 1292 C C . ALA A 1 221 ? -45.603 -10.041 29.646 1.00 30.85 ? 194 ALA A C 1 ATOM 1293 O O . ALA A 1 221 ? -46.044 -10.151 30.780 1.00 29.76 ? 194 ALA A O 1 ATOM 1294 C CB . ALA A 1 221 ? -43.845 -8.300 29.230 1.00 28.51 ? 194 ALA A CB 1 ATOM 1295 N N . THR A 1 222 ? -46.372 -10.129 28.569 1.00 30.75 ? 195 THR A N 1 ATOM 1296 C CA . THR A 1 222 ? -47.788 -10.440 28.663 1.00 30.29 ? 195 THR A CA 1 ATOM 1297 C C . THR A 1 222 ? -47.987 -11.834 29.278 1.00 31.92 ? 195 THR A C 1 ATOM 1298 O O . THR A 1 222 ? -48.855 -12.039 30.122 1.00 32.74 ? 195 THR A O 1 ATOM 1299 C CB . THR A 1 222 ? -48.454 -10.337 27.273 1.00 31.29 ? 195 THR A CB 1 ATOM 1300 O OG1 . THR A 1 222 ? -48.179 -9.063 26.721 1.00 31.28 ? 195 THR A OG1 1 ATOM 1301 C CG2 . THR A 1 222 ? -49.955 -10.493 27.340 1.00 31.30 ? 195 THR A CG2 1 ATOM 1302 N N . ALA A 1 223 ? -47.185 -12.789 28.843 1.00 32.48 ? 196 ALA A N 1 ATOM 1303 C CA . ALA A 1 223 ? -47.269 -14.149 29.328 1.00 31.92 ? 196 ALA A CA 1 ATOM 1304 C C . ALA A 1 223 ? -47.047 -14.210 30.811 1.00 34.23 ? 196 ALA A C 1 ATOM 1305 O O . ALA A 1 223 ? -47.698 -14.993 31.503 1.00 33.04 ? 196 ALA A O 1 ATOM 1306 C CB . ALA A 1 223 ? -46.262 -15.033 28.617 1.00 31.61 ? 196 ALA A CB 1 ATOM 1307 N N . MET A 1 224 ? -46.108 -13.408 31.301 1.00 34.58 ? 197 MET A N 1 ATOM 1308 C CA . MET A 1 224 ? -45.869 -13.336 32.734 1.00 35.07 ? 197 MET A CA 1 ATOM 1309 C C . MET A 1 224 ? -47.139 -12.885 33.456 1.00 34.75 ? 197 MET A C 1 ATOM 1310 O O . MET A 1 224 ? -47.496 -13.439 34.491 1.00 33.23 ? 197 MET A O 1 ATOM 1311 C CB . MET A 1 224 ? -44.729 -12.382 33.047 1.00 38.32 ? 197 MET A CB 1 ATOM 1312 C CG . MET A 1 224 ? -43.348 -12.952 32.811 1.00 39.91 ? 197 MET A CG 1 ATOM 1313 S SD . MET A 1 224 ? -42.134 -11.617 32.767 1.00 46.80 ? 197 MET A SD 1 ATOM 1314 C CE . MET A 1 224 ? -40.610 -12.558 32.826 1.00 43.05 ? 197 MET A CE 1 ATOM 1315 N N . ALA A 1 225 ? -47.825 -11.885 32.920 1.00 34.20 ? 198 ALA A N 1 ATOM 1316 C CA . ALA A 1 225 ? -49.099 -11.448 33.522 1.00 35.74 ? 198 ALA A CA 1 ATOM 1317 C C . ALA A 1 225 ? -50.172 -12.556 33.444 1.00 35.69 ? 198 ALA A C 1 ATOM 1318 O O . ALA A 1 225 ? -50.924 -12.763 34.405 1.00 31.72 ? 198 ALA A O 1 ATOM 1319 C CB . ALA A 1 225 ? -49.596 -10.161 32.884 1.00 36.38 ? 198 ALA A CB 1 ATOM 1320 N N . ASP A 1 226 ? -50.220 -13.262 32.313 1.00 36.68 ? 199 ASP A N 1 ATOM 1321 C CA . ASP A 1 226 ? -51.182 -14.363 32.110 1.00 37.35 ? 199 ASP A CA 1 ATOM 1322 C C . ASP A 1 226 ? -50.990 -15.486 33.124 1.00 38.49 ? 199 ASP A C 1 ATOM 1323 O O . ASP A 1 226 ? -51.971 -16.010 33.684 1.00 37.22 ? 199 ASP A O 1 ATOM 1324 C CB . ASP A 1 226 ? -51.071 -14.937 30.709 1.00 36.43 ? 199 ASP A CB 1 ATOM 1325 C CG . ASP A 1 226 ? -51.827 -14.137 29.696 1.00 37.71 ? 199 ASP A CG 1 ATOM 1326 O OD1 . ASP A 1 226 ? -52.672 -13.308 30.101 1.00 40.56 ? 199 ASP A OD1 1 ATOM 1327 O OD2 . ASP A 1 226 ? -51.582 -14.339 28.487 1.00 36.24 ? 199 ASP A OD2 1 ATOM 1328 N N . ILE A 1 227 ? -49.732 -15.819 33.386 1.00 34.85 ? 200 ILE A N 1 ATOM 1329 C CA . ILE A 1 227 ? -49.429 -16.861 34.330 1.00 35.49 ? 200 ILE A CA 1 ATOM 1330 C C . ILE A 1 227 ? -49.903 -16.481 35.751 1.00 38.05 ? 200 ILE A C 1 ATOM 1331 O O . ILE A 1 227 ? -50.500 -17.290 36.475 1.00 36.34 ? 200 ILE A O 1 ATOM 1332 C CB . ILE A 1 227 ? -47.920 -17.140 34.355 1.00 34.03 ? 200 ILE A CB 1 ATOM 1333 C CG1 . ILE A 1 227 ? -47.488 -17.867 33.071 1.00 34.98 ? 200 ILE A CG1 1 ATOM 1334 C CG2 . ILE A 1 227 ? -47.567 -17.975 35.560 1.00 34.25 ? 200 ILE A CG2 1 ATOM 1335 C CD1 . ILE A 1 227 ? -45.989 -18.124 32.969 1.00 34.57 ? 200 ILE A CD1 1 ATOM 1336 N N . ILE A 1 228 ? -49.577 -15.266 36.161 1.00 35.98 ? 201 ILE A N 1 ATOM 1337 C CA . ILE A 1 228 ? -49.982 -14.767 37.461 1.00 36.77 ? 201 ILE A CA 1 ATOM 1338 C C . ILE A 1 228 ? -51.516 -14.812 37.595 1.00 35.30 ? 201 ILE A C 1 ATOM 1339 O O . ILE A 1 228 ? -52.019 -15.292 38.576 1.00 32.48 ? 201 ILE A O 1 ATOM 1340 C CB . ILE A 1 228 ? -49.431 -13.343 37.703 1.00 36.18 ? 201 ILE A CB 1 ATOM 1341 C CG1 . ILE A 1 228 ? -47.916 -13.416 37.900 1.00 36.07 ? 201 ILE A CG1 1 ATOM 1342 C CG2 . ILE A 1 228 ? -50.092 -12.680 38.909 1.00 37.77 ? 201 ILE A CG2 1 ATOM 1343 C CD1 . ILE A 1 228 ? -47.241 -12.057 37.820 1.00 36.18 ? 201 ILE A CD1 1 ATOM 1344 N N . GLU A 1 229 ? -52.230 -14.305 36.597 1.00 35.67 ? 202 GLU A N 1 ATOM 1345 C CA . GLU A 1 229 ? -53.684 -14.337 36.576 1.00 38.91 ? 202 GLU A CA 1 ATOM 1346 C C . GLU A 1 229 ? -54.219 -15.770 36.651 1.00 42.46 ? 202 GLU A C 1 ATOM 1347 O O . GLU A 1 229 ? -55.213 -16.016 37.321 1.00 40.69 ? 202 GLU A O 1 ATOM 1348 C CB . GLU A 1 229 ? -54.192 -13.657 35.316 1.00 41.83 ? 202 GLU A CB 1 ATOM 1349 C CG . GLU A 1 229 ? -55.696 -13.626 35.138 1.00 42.61 ? 202 GLU A CG 1 ATOM 1350 C CD . GLU A 1 229 ? -56.081 -13.081 33.783 1.00 45.47 ? 202 GLU A CD 1 ATOM 1351 O OE1 . GLU A 1 229 ? -55.371 -13.357 32.787 1.00 46.90 ? 202 GLU A OE1 1 ATOM 1352 O OE2 . GLU A 1 229 ? -57.099 -12.377 33.698 1.00 52.55 ? 202 GLU A OE2 1 ATOM 1353 N N . TYR A 1 230 ? -53.541 -16.702 35.979 1.00 42.16 ? 203 TYR A N 1 ATOM 1354 C CA . TYR A 1 230 ? -53.905 -18.112 36.009 1.00 41.65 ? 203 TYR A CA 1 ATOM 1355 C C . TYR A 1 230 ? -53.890 -18.699 37.426 1.00 40.86 ? 203 TYR A C 1 ATOM 1356 O O . TYR A 1 230 ? -54.842 -19.371 37.846 1.00 43.78 ? 203 TYR A O 1 ATOM 1357 C CB . TYR A 1 230 ? -52.973 -18.919 35.106 1.00 42.40 ? 203 TYR A CB 1 ATOM 1358 C CG . TYR A 1 230 ? -53.315 -20.381 35.036 1.00 43.52 ? 203 TYR A CG 1 ATOM 1359 C CD1 . TYR A 1 230 ? -54.285 -20.840 34.154 1.00 47.04 ? 203 TYR A CD1 1 ATOM 1360 C CD2 . TYR A 1 230 ? -52.692 -21.300 35.869 1.00 44.27 ? 203 TYR A CD2 1 ATOM 1361 C CE1 . TYR A 1 230 ? -54.615 -22.182 34.089 1.00 47.30 ? 203 TYR A CE1 1 ATOM 1362 C CE2 . TYR A 1 230 ? -53.012 -22.645 35.816 1.00 47.86 ? 203 TYR A CE2 1 ATOM 1363 C CZ . TYR A 1 230 ? -53.978 -23.080 34.920 1.00 47.92 ? 203 TYR A CZ 1 ATOM 1364 O OH . TYR A 1 230 ? -54.331 -24.406 34.873 1.00 49.21 ? 203 TYR A OH 1 ATOM 1365 N N . PHE A 1 231 ? -52.816 -18.455 38.156 1.00 35.89 ? 204 PHE A N 1 ATOM 1366 C CA . PHE A 1 231 ? -52.706 -18.927 39.529 1.00 37.75 ? 204 PHE A CA 1 ATOM 1367 C C . PHE A 1 231 ? -53.382 -18.017 40.553 1.00 37.56 ? 204 PHE A C 1 ATOM 1368 O O . PHE A 1 231 ? -53.289 -18.283 41.753 1.00 40.55 ? 204 PHE A O 1 ATOM 1369 C CB . PHE A 1 231 ? -51.250 -19.139 39.929 1.00 37.02 ? 204 PHE A CB 1 ATOM 1370 C CG . PHE A 1 231 ? -50.615 -20.315 39.264 1.00 38.07 ? 204 PHE A CG 1 ATOM 1371 C CD1 . PHE A 1 231 ? -50.855 -21.607 39.724 1.00 41.38 ? 204 PHE A CD1 1 ATOM 1372 C CD2 . PHE A 1 231 ? -49.791 -20.137 38.174 1.00 38.23 ? 204 PHE A CD2 1 ATOM 1373 C CE1 . PHE A 1 231 ? -50.262 -22.704 39.100 1.00 41.21 ? 204 PHE A CE1 1 ATOM 1374 C CE2 . PHE A 1 231 ? -49.198 -21.216 37.545 1.00 40.74 ? 204 PHE A CE2 1 ATOM 1375 C CZ . PHE A 1 231 ? -49.431 -22.503 38.005 1.00 40.82 ? 204 PHE A CZ 1 ATOM 1376 N N . ARG A 1 232 ? -54.056 -16.958 40.097 1.00 37.60 ? 205 ARG A N 1 ATOM 1377 C CA . ARG A 1 232 ? -54.717 -16.036 41.004 1.00 42.13 ? 205 ARG A CA 1 ATOM 1378 C C . ARG A 1 232 ? -53.754 -15.383 42.001 1.00 42.65 ? 205 ARG A C 1 ATOM 1379 O O . ARG A 1 232 ? -54.142 -15.017 43.109 1.00 44.25 ? 205 ARG A O 1 ATOM 1380 C CB . ARG A 1 232 ? -55.844 -16.783 41.746 1.00 45.88 ? 205 ARG A CB 1 ATOM 1381 C CG . ARG A 1 232 ? -57.200 -16.530 41.149 1.00 48.12 ? 205 ARG A CG 1 ATOM 1382 C CD . ARG A 1 232 ? -57.440 -17.094 39.751 1.00 49.59 ? 205 ARG A CD 1 ATOM 1383 N NE . ARG A 1 232 ? -57.812 -18.505 39.804 1.00 53.46 ? 205 ARG A NE 1 ATOM 1384 C CZ . ARG A 1 232 ? -58.641 -19.120 38.955 1.00 51.68 ? 205 ARG A CZ 1 ATOM 1385 N NH1 . ARG A 1 232 ? -59.208 -18.471 37.954 1.00 50.30 ? 205 ARG A NH1 1 ATOM 1386 N NH2 . ARG A 1 232 ? -58.904 -20.408 39.115 1.00 54.37 ? 205 ARG A NH2 1 ATOM 1387 N N . TRP A 1 233 ? -52.492 -15.246 41.615 1.00 39.83 ? 206 TRP A N 1 ATOM 1388 C CA . TRP A 1 233 ? -51.539 -14.530 42.450 1.00 37.80 ? 206 TRP A CA 1 ATOM 1389 C C . TRP A 1 233 ? -51.752 -13.020 42.402 1.00 34.97 ? 206 TRP A C 1 ATOM 1390 O O . TRP A 1 233 ? -52.371 -12.496 41.494 1.00 32.36 ? 206 TRP A O 1 ATOM 1391 C CB . TRP A 1 233 ? -50.126 -14.854 42.031 1.00 38.93 ? 206 TRP A CB 1 ATOM 1392 C CG . TRP A 1 233 ? -49.743 -16.261 42.209 1.00 40.20 ? 206 TRP A CG 1 ATOM 1393 C CD1 . TRP A 1 233 ? -50.208 -17.126 43.156 1.00 41.11 ? 206 TRP A CD1 1 ATOM 1394 C CD2 . TRP A 1 233 ? -48.762 -16.984 41.448 1.00 41.31 ? 206 TRP A CD2 1 ATOM 1395 N NE1 . TRP A 1 233 ? -49.571 -18.342 43.030 1.00 41.89 ? 206 TRP A NE1 1 ATOM 1396 C CE2 . TRP A 1 233 ? -48.686 -18.282 41.986 1.00 41.81 ? 206 TRP A CE2 1 ATOM 1397 C CE3 . TRP A 1 233 ? -47.948 -16.657 40.359 1.00 41.97 ? 206 TRP A CE3 1 ATOM 1398 C CZ2 . TRP A 1 233 ? -47.829 -19.250 41.473 1.00 43.55 ? 206 TRP A CZ2 1 ATOM 1399 C CZ3 . TRP A 1 233 ? -47.096 -17.609 39.850 1.00 41.24 ? 206 TRP A CZ3 1 ATOM 1400 C CH2 . TRP A 1 233 ? -47.037 -18.890 40.402 1.00 43.85 ? 206 TRP A CH2 1 ATOM 1401 N N . ASN A 1 234 ? -51.302 -12.336 43.445 1.00 35.53 ? 207 ASN A N 1 ATOM 1402 C CA . ASN A 1 234 ? -51.409 -10.905 43.506 1.00 36.72 ? 207 ASN A CA 1 ATOM 1403 C C . ASN A 1 234 ? -50.373 -10.314 44.443 1.00 36.46 ? 207 ASN A C 1 ATOM 1404 O O . ASN A 1 234 ? -49.604 -11.063 45.050 1.00 38.29 ? 207 ASN A O 1 ATOM 1405 C CB . ASN A 1 234 ? -52.823 -10.495 43.868 1.00 38.44 ? 207 ASN A CB 1 ATOM 1406 C CG . ASN A 1 234 ? -53.238 -9.255 43.135 1.00 37.70 ? 207 ASN A CG 1 ATOM 1407 O OD1 . ASN A 1 234 ? -52.541 -8.251 43.198 1.00 39.42 ? 207 ASN A OD1 1 ATOM 1408 N ND2 . ASN A 1 234 ? -54.316 -9.323 42.387 1.00 39.04 ? 207 ASN A ND2 1 ATOM 1409 N N . TRP A 1 235 ? -50.288 -8.984 44.505 1.00 36.89 ? 208 TRP A N 1 ATOM 1410 C CA . TRP A 1 235 ? -49.201 -8.292 45.263 1.00 38.53 ? 208 TRP A CA 1 ATOM 1411 C C . TRP A 1 235 ? -47.838 -8.945 44.988 1.00 36.82 ? 208 TRP A C 1 ATOM 1412 O O . TRP A 1 235 ? -47.167 -9.486 45.879 1.00 39.79 ? 208 TRP A O 1 ATOM 1413 C CB . TRP A 1 235 ? -49.537 -8.178 46.749 1.00 37.61 ? 208 TRP A CB 1 ATOM 1414 C CG . TRP A 1 235 ? -50.693 -7.268 46.936 1.00 38.75 ? 208 TRP A CG 1 ATOM 1415 C CD1 . TRP A 1 235 ? -51.977 -7.620 47.213 1.00 37.55 ? 208 TRP A CD1 1 ATOM 1416 C CD2 . TRP A 1 235 ? -50.689 -5.842 46.777 1.00 38.82 ? 208 TRP A CD2 1 ATOM 1417 N NE1 . TRP A 1 235 ? -52.772 -6.500 47.258 1.00 38.22 ? 208 TRP A NE1 1 ATOM 1418 C CE2 . TRP A 1 235 ? -52.007 -5.395 46.986 1.00 39.60 ? 208 TRP A CE2 1 ATOM 1419 C CE3 . TRP A 1 235 ? -49.698 -4.904 46.478 1.00 40.56 ? 208 TRP A CE3 1 ATOM 1420 C CZ2 . TRP A 1 235 ? -52.361 -4.040 46.923 1.00 40.03 ? 208 TRP A CZ2 1 ATOM 1421 C CZ3 . TRP A 1 235 ? -50.047 -3.554 46.417 1.00 41.49 ? 208 TRP A CZ3 1 ATOM 1422 C CH2 . TRP A 1 235 ? -51.368 -3.138 46.636 1.00 41.61 ? 208 TRP A CH2 1 ATOM 1423 N N . VAL A 1 236 ? -47.461 -8.881 43.714 1.00 33.10 ? 209 VAL A N 1 ATOM 1424 C CA . VAL A 1 236 ? -46.192 -9.469 43.234 1.00 34.19 ? 209 VAL A CA 1 ATOM 1425 C C . VAL A 1 236 ? -45.104 -8.420 43.341 1.00 33.18 ? 209 VAL A C 1 ATOM 1426 O O . VAL A 1 236 ? -45.406 -7.242 43.446 1.00 35.23 ? 209 VAL A O 1 ATOM 1427 C CB . VAL A 1 236 ? -46.228 -9.946 41.755 1.00 35.12 ? 209 VAL A CB 1 ATOM 1428 C CG1 . VAL A 1 236 ? -47.342 -10.950 41.514 1.00 36.65 ? 209 VAL A CG1 1 ATOM 1429 C CG2 . VAL A 1 236 ? -46.387 -8.789 40.787 1.00 34.58 ? 209 VAL A CG2 1 ATOM 1430 N N . GLY A 1 237 ? -43.846 -8.847 43.302 1.00 32.19 ? 210 GLY A N 1 ATOM 1431 C CA . GLY A 1 237 ? -42.724 -7.910 43.242 1.00 32.82 ? 210 GLY A CA 1 ATOM 1432 C C . GLY A 1 237 ? -42.143 -7.932 41.841 1.00 33.28 ? 210 GLY A C 1 ATOM 1433 O O . GLY A 1 237 ? -42.336 -8.920 41.099 1.00 32.79 ? 210 GLY A O 1 ATOM 1434 N N . THR A 1 238 ? -41.497 -6.828 41.448 1.00 32.80 ? 211 THR A N 1 ATOM 1435 C CA . THR A 1 238 ? -40.758 -6.786 40.174 1.00 30.64 ? 211 THR A CA 1 ATOM 1436 C C . THR A 1 238 ? -39.313 -6.295 40.333 1.00 29.82 ? 211 THR A C 1 ATOM 1437 O O . THR A 1 238 ? -38.993 -5.438 41.165 1.00 29.35 ? 211 THR A O 1 ATOM 1438 C CB . THR A 1 238 ? -41.432 -5.921 39.100 1.00 30.51 ? 211 THR A CB 1 ATOM 1439 O OG1 . THR A 1 238 ? -41.417 -4.552 39.504 1.00 32.36 ? 211 THR A OG1 1 ATOM 1440 C CG2 . THR A 1 238 ? -42.857 -6.355 38.807 1.00 30.60 ? 211 THR A CG2 1 ATOM 1441 N N . ILE A 1 239 ? -38.436 -6.887 39.538 1.00 29.79 ? 212 ILE A N 1 ATOM 1442 C CA . ILE A 1 239 ? -37.032 -6.512 39.498 1.00 30.08 ? 212 ILE A CA 1 ATOM 1443 C C . ILE A 1 239 ? -36.624 -6.504 38.040 1.00 30.88 ? 212 ILE A C 1 ATOM 1444 O O . ILE A 1 239 ? -36.917 -7.449 37.293 1.00 28.84 ? 212 ILE A O 1 ATOM 1445 C CB . ILE A 1 239 ? -36.157 -7.500 40.262 1.00 32.96 ? 212 ILE A CB 1 ATOM 1446 C CG1 . ILE A 1 239 ? -36.556 -7.489 41.739 1.00 34.33 ? 212 ILE A CG1 1 ATOM 1447 C CG2 . ILE A 1 239 ? -34.670 -7.148 40.115 1.00 33.84 ? 212 ILE A CG2 1 ATOM 1448 C CD1 . ILE A 1 239 ? -35.911 -8.587 42.540 1.00 36.51 ? 212 ILE A CD1 1 ATOM 1449 N N . ALA A 1 240 ? -35.917 -5.458 37.646 1.00 29.38 ? 213 ALA A N 1 ATOM 1450 C CA . ALA A 1 240 ? -35.488 -5.320 36.267 1.00 27.94 ? 213 ALA A CA 1 ATOM 1451 C C . ALA A 1 240 ? -34.044 -4.826 36.206 1.00 27.77 ? 213 ALA A C 1 ATOM 1452 O O . ALA A 1 240 ? -33.607 -4.008 37.028 1.00 28.18 ? 213 ALA A O 1 ATOM 1453 C CB . ALA A 1 240 ? -36.403 -4.347 35.567 1.00 27.82 ? 213 ALA A CB 1 ATOM 1454 N N . ALA A 1 241 ? -33.304 -5.340 35.247 1.00 25.59 ? 214 ALA A N 1 ATOM 1455 C CA . ALA A 1 241 ? -31.990 -4.814 34.930 1.00 25.69 ? 214 ALA A CA 1 ATOM 1456 C C . ALA A 1 241 ? -32.203 -3.385 34.470 1.00 26.12 ? 214 ALA A C 1 ATOM 1457 O O . ALA A 1 241 ? -33.142 -3.102 33.715 1.00 26.27 ? 214 ALA A O 1 ATOM 1458 C CB . ALA A 1 241 ? -31.341 -5.648 33.840 1.00 24.09 ? 214 ALA A CB 1 ATOM 1459 N N . ASP A 1 242 ? -31.354 -2.478 34.937 1.00 26.16 ? 215 ASP A N 1 ATOM 1460 C CA . ASP A 1 242 ? -31.512 -1.056 34.653 1.00 27.14 ? 215 ASP A CA 1 ATOM 1461 C C . ASP A 1 242 ? -30.904 -0.734 33.303 1.00 29.10 ? 215 ASP A C 1 ATOM 1462 O O . ASP A 1 242 ? -29.893 -0.047 33.213 1.00 29.69 ? 215 ASP A O 1 ATOM 1463 C CB . ASP A 1 242 ? -30.851 -0.198 35.743 1.00 27.18 ? 215 ASP A CB 1 ATOM 1464 C CG . ASP A 1 242 ? -31.270 1.274 35.678 1.00 28.60 ? 215 ASP A CG 1 ATOM 1465 O OD1 . ASP A 1 242 ? -32.212 1.650 34.937 1.00 26.20 ? 215 ASP A OD1 1 ATOM 1466 O OD2 . ASP A 1 242 ? -30.626 2.094 36.361 1.00 30.63 ? 215 ASP A OD2 1 ATOM 1467 N N . ASP A 1 243 ? -31.554 -1.212 32.253 1.00 28.50 ? 216 ASP A N 1 ATOM 1468 C CA . ASP A 1 243 ? -31.062 -1.032 30.898 1.00 29.54 ? 216 ASP A CA 1 ATOM 1469 C C . ASP A 1 243 ? -32.234 -1.172 29.926 1.00 27.56 ? 216 ASP A C 1 ATOM 1470 O O . ASP A 1 243 ? -33.396 -1.270 30.347 1.00 27.42 ? 216 ASP A O 1 ATOM 1471 C CB . ASP A 1 243 ? -29.942 -2.066 30.606 1.00 30.59 ? 216 ASP A CB 1 ATOM 1472 C CG . ASP A 1 243 ? -30.452 -3.538 30.650 1.00 32.16 ? 216 ASP A CG 1 ATOM 1473 O OD1 . ASP A 1 243 ? -31.649 -3.807 30.419 1.00 32.31 ? 216 ASP A OD1 1 ATOM 1474 O OD2 . ASP A 1 243 ? -29.646 -4.433 30.917 1.00 39.55 ? 216 ASP A OD2 1 ATOM 1475 N N . ASP A 1 244 ? -31.947 -1.173 28.634 1.00 25.56 ? 217 ASP A N 1 ATOM 1476 C CA . ASP A 1 244 ? -33.009 -1.188 27.617 1.00 27.38 ? 217 ASP A CA 1 ATOM 1477 C C . ASP A 1 244 ? -33.668 -2.528 27.433 1.00 27.09 ? 217 ASP A C 1 ATOM 1478 O O . ASP A 1 244 ? -34.573 -2.645 26.626 1.00 27.12 ? 217 ASP A O 1 ATOM 1479 C CB . ASP A 1 244 ? -32.461 -0.705 26.270 1.00 30.19 ? 217 ASP A CB 1 ATOM 1480 C CG . ASP A 1 244 ? -32.261 0.809 26.219 1.00 32.63 ? 217 ASP A CG 1 ATOM 1481 O OD1 . ASP A 1 244 ? -32.907 1.538 26.996 1.00 36.09 ? 217 ASP A OD1 1 ATOM 1482 O OD2 . ASP A 1 244 ? -31.484 1.265 25.363 1.00 37.45 ? 217 ASP A OD2 1 ATOM 1483 N N . TYR A 1 245 ? -33.206 -3.557 28.149 1.00 26.41 ? 218 TYR A N 1 ATOM 1484 C CA . TYR A 1 245 ? -33.902 -4.853 28.180 1.00 25.75 ? 218 TYR A CA 1 ATOM 1485 C C . TYR A 1 245 ? -34.856 -4.891 29.355 1.00 25.03 ? 218 TYR A C 1 ATOM 1486 O O . TYR A 1 245 ? -36.055 -5.077 29.195 1.00 25.72 ? 218 TYR A O 1 ATOM 1487 C CB . TYR A 1 245 ? -32.899 -6.001 28.277 1.00 27.07 ? 218 TYR A CB 1 ATOM 1488 C CG . TYR A 1 245 ? -33.475 -7.389 28.527 1.00 26.93 ? 218 TYR A CG 1 ATOM 1489 C CD1 . TYR A 1 245 ? -34.325 -7.996 27.601 1.00 27.86 ? 218 TYR A CD1 1 ATOM 1490 C CD2 . TYR A 1 245 ? -33.107 -8.124 29.633 1.00 28.32 ? 218 TYR A CD2 1 ATOM 1491 C CE1 . TYR A 1 245 ? -34.829 -9.268 27.805 1.00 27.42 ? 218 TYR A CE1 1 ATOM 1492 C CE2 . TYR A 1 245 ? -33.613 -9.426 29.840 1.00 30.13 ? 218 TYR A CE2 1 ATOM 1493 C CZ . TYR A 1 245 ? -34.464 -9.984 28.918 1.00 27.88 ? 218 TYR A CZ 1 ATOM 1494 O OH . TYR A 1 245 ? -34.977 -11.243 29.096 1.00 31.43 ? 218 TYR A OH 1 ATOM 1495 N N . GLY A 1 246 ? -34.307 -4.689 30.538 1.00 23.44 ? 219 GLY A N 1 ATOM 1496 C CA . GLY A 1 246 ? -35.081 -4.796 31.753 1.00 25.64 ? 219 GLY A CA 1 ATOM 1497 C C . GLY A 1 246 ? -36.194 -3.782 31.914 1.00 25.49 ? 219 GLY A C 1 ATOM 1498 O O . GLY A 1 246 ? -37.318 -4.147 32.266 1.00 28.15 ? 219 GLY A O 1 ATOM 1499 N N . ARG A 1 247 ? -35.904 -2.509 31.679 1.00 26.10 ? 220 ARG A N 1 ATOM 1500 C CA . ARG A 1 247 ? -36.916 -1.472 31.945 1.00 26.22 ? 220 ARG A CA 1 ATOM 1501 C C . ARG A 1 247 ? -38.149 -1.578 31.028 1.00 26.34 ? 220 ARG A C 1 ATOM 1502 O O . ARG A 1 247 ? -39.261 -1.523 31.502 1.00 26.60 ? 220 ARG A O 1 ATOM 1503 C CB . ARG A 1 247 ? -36.307 -0.069 31.880 1.00 27.58 ? 220 ARG A CB 1 ATOM 1504 C CG . ARG A 1 247 ? -35.292 0.220 32.980 1.00 27.20 ? 220 ARG A CG 1 ATOM 1505 C CD . ARG A 1 247 ? -34.804 1.656 32.907 1.00 27.17 ? 220 ARG A CD 1 ATOM 1506 N NE . ARG A 1 247 ? -34.279 2.000 31.587 1.00 27.35 ? 220 ARG A NE 1 ATOM 1507 C CZ . ARG A 1 247 ? -32.998 2.177 31.287 1.00 28.89 ? 220 ARG A CZ 1 ATOM 1508 N NH1 . ARG A 1 247 ? -32.051 2.086 32.197 1.00 31.88 ? 220 ARG A NH1 1 ATOM 1509 N NH2 . ARG A 1 247 ? -32.655 2.451 30.049 1.00 33.32 ? 220 ARG A NH2 1 ATOM 1510 N N . PRO A 1 248 ? -37.962 -1.733 29.719 1.00 25.35 ? 221 PRO A N 1 ATOM 1511 C CA . PRO A 1 248 ? -39.169 -1.886 28.883 1.00 26.98 ? 221 PRO A CA 1 ATOM 1512 C C . PRO A 1 248 ? -39.914 -3.229 29.042 1.00 27.36 ? 221 PRO A C 1 ATOM 1513 O O . PRO A 1 248 ? -41.103 -3.293 28.797 1.00 30.23 ? 221 PRO A O 1 ATOM 1514 C CB . PRO A 1 248 ? -38.645 -1.721 27.448 1.00 26.30 ? 221 PRO A CB 1 ATOM 1515 C CG . PRO A 1 248 ? -37.218 -1.374 27.576 1.00 27.43 ? 221 PRO A CG 1 ATOM 1516 C CD . PRO A 1 248 ? -36.726 -1.684 28.931 1.00 25.94 ? 221 PRO A CD 1 ATOM 1517 N N . GLY A 1 249 ? -39.215 -4.292 29.403 1.00 29.12 ? 222 GLY A N 1 ATOM 1518 C CA . GLY A 1 249 ? -39.874 -5.574 29.671 1.00 28.04 ? 222 GLY A CA 1 ATOM 1519 C C . GLY A 1 249 ? -40.800 -5.448 30.875 1.00 30.32 ? 222 GLY A C 1 ATOM 1520 O O . GLY A 1 249 ? -41.964 -5.851 30.839 1.00 27.28 ? 222 GLY A O 1 ATOM 1521 N N . ILE A 1 250 ? -40.280 -4.847 31.933 1.00 29.00 ? 223 ILE A N 1 ATOM 1522 C CA . ILE A 1 250 ? -41.055 -4.682 33.124 1.00 30.49 ? 223 ILE A CA 1 ATOM 1523 C C . ILE A 1 250 ? -42.159 -3.638 32.960 1.00 29.52 ? 223 ILE A C 1 ATOM 1524 O O . ILE A 1 250 ? -43.212 -3.774 33.576 1.00 27.77 ? 223 ILE A O 1 ATOM 1525 C CB . ILE A 1 250 ? -40.130 -4.472 34.364 1.00 35.08 ? 223 ILE A CB 1 ATOM 1526 C CG1 . ILE A 1 250 ? -40.727 -5.167 35.554 1.00 39.86 ? 223 ILE A CG1 1 ATOM 1527 C CG2 . ILE A 1 250 ? -39.880 -3.006 34.667 1.00 40.47 ? 223 ILE A CG2 1 ATOM 1528 C CD1 . ILE A 1 250 ? -40.661 -6.681 35.447 1.00 37.40 ? 223 ILE A CD1 1 ATOM 1529 N N . GLU A 1 251 ? -41.940 -2.613 32.134 1.00 28.84 ? 224 GLU A N 1 ATOM 1530 C CA . GLU A 1 251 ? -42.965 -1.607 31.854 1.00 31.46 ? 224 GLU A CA 1 ATOM 1531 C C . GLU A 1 251 ? -44.176 -2.242 31.160 1.00 32.61 ? 224 GLU A C 1 ATOM 1532 O O . GLU A 1 251 ? -45.314 -1.871 31.454 1.00 28.66 ? 224 GLU A O 1 ATOM 1533 C CB . GLU A 1 251 ? -42.386 -0.428 31.021 1.00 36.24 ? 224 GLU A CB 1 ATOM 1534 C CG . GLU A 1 251 ? -43.342 0.483 30.202 1.00 40.72 ? 224 GLU A CG 1 ATOM 1535 C CD . GLU A 1 251 ? -42.633 1.427 29.162 1.00 46.12 ? 224 GLU A CD 1 ATOM 1536 O OE1 . GLU A 1 251 ? -41.656 1.039 28.415 1.00 39.57 ? 224 GLU A OE1 1 ATOM 1537 O OE2 . GLU A 1 251 ? -43.085 2.602 29.056 1.00 52.05 ? 224 GLU A OE2 1 ATOM 1538 N N . LYS A 1 252 ? -43.920 -3.154 30.216 1.00 30.24 ? 225 LYS A N 1 ATOM 1539 C CA . LYS A 1 252 ? -44.984 -3.859 29.505 1.00 30.47 ? 225 LYS A CA 1 ATOM 1540 C C . LYS A 1 252 ? -45.681 -4.787 30.489 1.00 31.58 ? 225 LYS A C 1 ATOM 1541 O O . LYS A 1 252 ? -46.904 -4.918 30.468 1.00 30.27 ? 225 LYS A O 1 ATOM 1542 C CB . LYS A 1 252 ? -44.438 -4.663 28.323 1.00 29.73 ? 225 LYS A CB 1 ATOM 1543 C CG . LYS A 1 252 ? -45.459 -5.518 27.591 1.00 30.03 ? 225 LYS A CG 1 ATOM 1544 C CD . LYS A 1 252 ? -46.638 -4.714 27.052 1.00 30.84 ? 225 LYS A CD 1 ATOM 1545 C CE . LYS A 1 252 ? -47.472 -5.591 26.119 1.00 32.61 ? 225 LYS A CE 1 ATOM 1546 N NZ . LYS A 1 252 ? -48.742 -4.934 25.715 1.00 34.04 ? 225 LYS A NZ 1 ATOM 1547 N N . PHE A 1 253 ? -44.898 -5.424 31.344 1.00 30.18 ? 226 PHE A N 1 ATOM 1548 C CA . PHE A 1 253 ? -45.475 -6.273 32.355 1.00 33.00 ? 226 PHE A CA 1 ATOM 1549 C C . PHE A 1 253 ? -46.406 -5.500 33.264 1.00 34.89 ? 226 PHE A C 1 ATOM 1550 O O . PHE A 1 253 ? -47.507 -5.959 33.573 1.00 34.79 ? 226 PHE A O 1 ATOM 1551 C CB . PHE A 1 253 ? -44.425 -6.969 33.200 1.00 32.55 ? 226 PHE A CB 1 ATOM 1552 C CG . PHE A 1 253 ? -45.018 -7.683 34.371 1.00 32.35 ? 226 PHE A CG 1 ATOM 1553 C CD1 . PHE A 1 253 ? -45.758 -8.855 34.181 1.00 33.18 ? 226 PHE A CD1 1 ATOM 1554 C CD2 . PHE A 1 253 ? -44.920 -7.151 35.646 1.00 31.76 ? 226 PHE A CD2 1 ATOM 1555 C CE1 . PHE A 1 253 ? -46.347 -9.503 35.248 1.00 32.22 ? 226 PHE A CE1 1 ATOM 1556 C CE2 . PHE A 1 253 ? -45.493 -7.806 36.725 1.00 32.33 ? 226 PHE A CE2 1 ATOM 1557 C CZ . PHE A 1 253 ? -46.211 -8.982 36.524 1.00 31.23 ? 226 PHE A CZ 1 ATOM 1558 N N . ARG A 1 254 ? -45.973 -4.323 33.687 1.00 35.39 ? 227 ARG A N 1 ATOM 1559 C CA . ARG A 1 254 ? -46.812 -3.484 34.510 1.00 36.97 ? 227 ARG A CA 1 ATOM 1560 C C . ARG A 1 254 ? -48.162 -3.163 33.819 1.00 35.35 ? 227 ARG A C 1 ATOM 1561 O O . ARG A 1 254 ? -49.208 -3.225 34.442 1.00 32.61 ? 227 ARG A O 1 ATOM 1562 C CB . ARG A 1 254 ? -46.096 -2.193 34.875 1.00 38.36 ? 227 ARG A CB 1 ATOM 1563 C CG . ARG A 1 254 ? -46.898 -1.379 35.855 1.00 39.74 ? 227 ARG A CG 1 ATOM 1564 C CD . ARG A 1 254 ? -46.144 -0.172 36.363 1.00 39.28 ? 227 ARG A CD 1 ATOM 1565 N NE . ARG A 1 254 ? -45.244 -0.562 37.460 1.00 39.14 ? 227 ARG A NE 1 ATOM 1566 C CZ . ARG A 1 254 ? -45.627 -0.674 38.737 1.00 36.83 ? 227 ARG A CZ 1 ATOM 1567 N NH1 . ARG A 1 254 ? -46.873 -0.428 39.087 1.00 39.93 ? 227 ARG A NH1 1 ATOM 1568 N NH2 . ARG A 1 254 ? -44.760 -1.020 39.670 1.00 34.55 ? 227 ARG A NH2 1 ATOM 1569 N N . GLU A 1 255 ? -48.121 -2.800 32.549 1.00 32.87 ? 228 GLU A N 1 ATOM 1570 C CA . GLU A 1 255 ? -49.337 -2.469 31.809 1.00 34.43 ? 228 GLU A CA 1 ATOM 1571 C C . GLU A 1 255 ? -50.313 -3.659 31.752 1.00 34.58 ? 228 GLU A C 1 ATOM 1572 O O . GLU A 1 255 ? -51.520 -3.515 31.967 1.00 33.38 ? 228 GLU A O 1 ATOM 1573 C CB . GLU A 1 255 ? -48.970 -2.008 30.404 1.00 34.58 ? 228 GLU A CB 1 ATOM 1574 C CG . GLU A 1 255 ? -50.143 -1.709 29.497 1.00 38.97 ? 228 GLU A CG 1 ATOM 1575 C CD . GLU A 1 255 ? -49.740 -1.573 28.029 1.00 44.17 ? 228 GLU A CD 1 ATOM 1576 O OE1 . GLU A 1 255 ? -48.580 -1.212 27.740 1.00 45.85 ? 228 GLU A OE1 1 ATOM 1577 O OE2 . GLU A 1 255 ? -50.596 -1.814 27.151 1.00 49.13 ? 228 GLU A OE2 1 ATOM 1578 N N . GLU A 1 256 ? -49.776 -4.839 31.477 1.00 35.09 ? 229 GLU A N 1 ATOM 1579 C CA . GLU A 1 256 ? -50.589 -6.033 31.394 1.00 36.88 ? 229 GLU A CA 1 ATOM 1580 C C . GLU A 1 256 ? -51.062 -6.473 32.763 1.00 40.36 ? 229 GLU A C 1 ATOM 1581 O O . GLU A 1 256 ? -52.188 -6.971 32.900 1.00 43.56 ? 229 GLU A O 1 ATOM 1582 C CB . GLU A 1 256 ? -49.825 -7.149 30.699 1.00 36.43 ? 229 GLU A CB 1 ATOM 1583 C CG . GLU A 1 256 ? -49.514 -6.803 29.261 1.00 38.14 ? 229 GLU A CG 1 ATOM 1584 C CD . GLU A 1 256 ? -50.762 -6.557 28.421 1.00 39.87 ? 229 GLU A CD 1 ATOM 1585 O OE1 . GLU A 1 256 ? -51.763 -7.251 28.639 1.00 40.11 ? 229 GLU A OE1 1 ATOM 1586 O OE2 . GLU A 1 256 ? -50.740 -5.663 27.538 1.00 42.39 ? 229 GLU A OE2 1 ATOM 1587 N N . ALA A 1 257 ? -50.234 -6.260 33.780 1.00 37.80 ? 230 ALA A N 1 ATOM 1588 C CA . ALA A 1 257 ? -50.614 -6.602 35.130 1.00 38.37 ? 230 ALA A CA 1 ATOM 1589 C C . ALA A 1 257 ? -51.787 -5.725 35.563 1.00 41.03 ? 230 ALA A C 1 ATOM 1590 O O . ALA A 1 257 ? -52.727 -6.224 36.176 1.00 40.46 ? 230 ALA A O 1 ATOM 1591 C CB . ALA A 1 257 ? -49.437 -6.457 36.083 1.00 37.23 ? 230 ALA A CB 1 ATOM 1592 N N . GLU A 1 258 ? -51.733 -4.439 35.239 1.00 40.10 ? 231 GLU A N 1 ATOM 1593 C CA . GLU A 1 258 ? -52.796 -3.502 35.596 1.00 43.23 ? 231 GLU A CA 1 ATOM 1594 C C . GLU A 1 258 ? -54.102 -3.934 34.934 1.00 47.84 ? 231 GLU A C 1 ATOM 1595 O O . GLU A 1 258 ? -55.141 -3.981 35.591 1.00 50.31 ? 231 GLU A O 1 ATOM 1596 C CB . GLU A 1 258 ? -52.440 -2.045 35.206 1.00 44.07 ? 231 GLU A CB 1 ATOM 1597 C CG . GLU A 1 258 ? -51.297 -1.393 36.015 1.00 49.62 ? 231 GLU A CG 1 ATOM 1598 C CD . GLU A 1 258 ? -50.571 -0.208 35.293 1.00 53.66 ? 231 GLU A CD 1 ATOM 1599 O OE1 . GLU A 1 258 ? -50.863 0.074 34.104 1.00 54.69 ? 231 GLU A OE1 1 ATOM 1600 O OE2 . GLU A 1 258 ? -49.686 0.453 35.910 1.00 51.63 ? 231 GLU A OE2 1 ATOM 1601 N N . GLU A 1 259 ? -54.032 -4.299 33.657 1.00 45.35 ? 232 GLU A N 1 ATOM 1602 C CA . GLU A 1 259 ? -55.192 -4.786 32.918 1.00 49.76 ? 232 GLU A CA 1 ATOM 1603 C C . GLU A 1 259 ? -55.875 -5.997 33.600 1.00 49.53 ? 232 GLU A C 1 ATOM 1604 O O . GLU A 1 259 ? -57.074 -6.200 33.446 1.00 46.05 ? 232 GLU A O 1 ATOM 1605 C CB . GLU A 1 259 ? -54.773 -5.194 31.511 1.00 55.22 ? 232 GLU A CB 1 ATOM 1606 C CG . GLU A 1 259 ? -55.830 -4.963 30.456 1.00 66.98 ? 232 GLU A CG 1 ATOM 1607 C CD . GLU A 1 259 ? -55.876 -3.498 30.032 1.00 73.93 ? 232 GLU A CD 1 ATOM 1608 O OE1 . GLU A 1 259 ? -54.787 -2.882 29.871 1.00 76.62 ? 232 GLU A OE1 1 ATOM 1609 O OE2 . GLU A 1 259 ? -56.994 -2.961 29.861 1.00 76.81 ? 232 GLU A OE2 1 ATOM 1610 N N . ARG A 1 260 ? -55.108 -6.787 34.346 1.00 41.64 ? 233 ARG A N 1 ATOM 1611 C CA . ARG A 1 260 ? -55.625 -7.973 34.985 1.00 40.69 ? 233 ARG A CA 1 ATOM 1612 C C . ARG A 1 260 ? -55.832 -7.783 36.486 1.00 41.93 ? 233 ARG A C 1 ATOM 1613 O O . ARG A 1 260 ? -55.995 -8.758 37.211 1.00 41.10 ? 233 ARG A O 1 ATOM 1614 C CB . ARG A 1 260 ? -54.666 -9.115 34.735 1.00 39.09 ? 233 ARG A CB 1 ATOM 1615 C CG . ARG A 1 260 ? -54.556 -9.507 33.271 1.00 39.72 ? 233 ARG A CG 1 ATOM 1616 C CD . ARG A 1 260 ? -53.258 -10.268 33.003 1.00 39.81 ? 233 ARG A CD 1 ATOM 1617 N NE . ARG A 1 260 ? -53.165 -10.771 31.628 1.00 39.68 ? 233 ARG A NE 1 ATOM 1618 C CZ . ARG A 1 260 ? -53.021 -10.009 30.554 1.00 39.30 ? 233 ARG A CZ 1 ATOM 1619 N NH1 . ARG A 1 260 ? -52.929 -8.688 30.652 1.00 39.68 ? 233 ARG A NH1 1 ATOM 1620 N NH2 . ARG A 1 260 ? -52.968 -10.566 29.364 1.00 42.66 ? 233 ARG A NH2 1 ATOM 1621 N N . ASP A 1 261 ? -55.826 -6.530 36.950 1.00 43.43 ? 234 ASP A N 1 ATOM 1622 C CA . ASP A 1 261 ? -55.939 -6.221 38.383 1.00 43.15 ? 234 ASP A CA 1 ATOM 1623 C C . ASP A 1 261 ? -54.921 -6.948 39.250 1.00 42.44 ? 234 ASP A C 1 ATOM 1624 O O . ASP A 1 261 ? -55.221 -7.360 40.378 1.00 43.59 ? 234 ASP A O 1 ATOM 1625 C CB . ASP A 1 261 ? -57.359 -6.488 38.891 1.00 43.87 ? 234 ASP A CB 1 ATOM 1626 C CG . ASP A 1 261 ? -58.396 -5.702 38.126 1.00 48.70 ? 234 ASP A CG 1 ATOM 1627 O OD1 . ASP A 1 261 ? -58.178 -4.499 37.869 1.00 54.02 ? 234 ASP A OD1 1 ATOM 1628 O OD2 . ASP A 1 261 ? -59.428 -6.283 37.748 1.00 56.63 ? 234 ASP A OD2 1 ATOM 1629 N N . ILE A 1 262 ? -53.710 -7.097 38.728 1.00 38.86 ? 235 ILE A N 1 ATOM 1630 C CA . ILE A 1 262 ? -52.589 -7.579 39.532 1.00 37.06 ? 235 ILE A CA 1 ATOM 1631 C C . ILE A 1 262 ? -51.896 -6.367 40.117 1.00 38.98 ? 235 ILE A C 1 ATOM 1632 O O . ILE A 1 262 ? -51.472 -5.487 39.376 1.00 39.13 ? 235 ILE A O 1 ATOM 1633 C CB . ILE A 1 262 ? -51.600 -8.374 38.679 1.00 38.89 ? 235 ILE A CB 1 ATOM 1634 C CG1 . ILE A 1 262 ? -52.297 -9.625 38.141 1.00 41.92 ? 235 ILE A CG1 1 ATOM 1635 C CG2 . ILE A 1 262 ? -50.372 -8.782 39.482 1.00 37.05 ? 235 ILE A CG2 1 ATOM 1636 C CD1 . ILE A 1 262 ? -51.587 -10.259 36.966 1.00 45.26 ? 235 ILE A CD1 1 HETATM 1637 N N . CSO A 1 263 ? -51.782 -6.337 41.442 1.00 37.98 ? 236 CSO A N 1 HETATM 1638 C CA . CSO A 1 263 ? -51.145 -5.247 42.163 1.00 38.41 ? 236 CSO A CA 1 HETATM 1639 C CB . CSO A 1 263 ? -51.814 -5.021 43.532 1.00 40.36 ? 236 CSO A CB 1 HETATM 1640 S SG . CSO A 1 263 ? -53.552 -4.703 43.357 1.00 44.32 ? 236 CSO A SG 1 HETATM 1641 C C . CSO A 1 263 ? -49.693 -5.601 42.350 1.00 37.07 ? 236 CSO A C 1 HETATM 1642 O O . CSO A 1 263 ? -49.344 -6.756 42.559 1.00 37.28 ? 236 CSO A O 1 HETATM 1643 O OD . CSO A 1 263 ? -53.719 -3.230 42.385 1.00 49.59 ? 236 CSO A OD 1 ATOM 1644 N N . ILE A 1 264 ? -48.826 -4.592 42.286 1.00 35.23 ? 237 ILE A N 1 ATOM 1645 C CA . ILE A 1 264 ? -47.372 -4.788 42.404 1.00 33.51 ? 237 ILE A CA 1 ATOM 1646 C C . ILE A 1 264 ? -46.890 -4.128 43.671 1.00 33.43 ? 237 ILE A C 1 ATOM 1647 O O . ILE A 1 264 ? -47.070 -2.941 43.837 1.00 35.41 ? 237 ILE A O 1 ATOM 1648 C CB . ILE A 1 264 ? -46.649 -4.209 41.156 1.00 31.96 ? 237 ILE A CB 1 ATOM 1649 C CG1 . ILE A 1 264 ? -47.107 -4.988 39.910 1.00 31.27 ? 237 ILE A CG1 1 ATOM 1650 C CG2 . ILE A 1 264 ? -45.118 -4.255 41.325 1.00 30.63 ? 237 ILE A CG2 1 ATOM 1651 C CD1 . ILE A 1 264 ? -46.746 -4.374 38.570 1.00 33.75 ? 237 ILE A CD1 1 ATOM 1652 N N . ASP A 1 265 ? -46.233 -4.888 44.536 1.00 35.52 ? 238 ASP A N 1 ATOM 1653 C CA . ASP A 1 265 ? -45.835 -4.401 45.852 1.00 38.62 ? 238 ASP A CA 1 ATOM 1654 C C . ASP A 1 265 ? -44.509 -3.635 45.836 1.00 37.47 ? 238 ASP A C 1 ATOM 1655 O O . ASP A 1 265 ? -44.291 -2.773 46.666 1.00 37.05 ? 238 ASP A O 1 ATOM 1656 C CB . ASP A 1 265 ? -45.731 -5.567 46.849 1.00 40.81 ? 238 ASP A CB 1 ATOM 1657 C CG . ASP A 1 265 ? -45.496 -5.094 48.283 1.00 43.23 ? 238 ASP A CG 1 ATOM 1658 O OD1 . ASP A 1 265 ? -46.302 -4.277 48.775 1.00 46.31 ? 238 ASP A OD1 1 ATOM 1659 O OD2 . ASP A 1 265 ? -44.499 -5.516 48.912 1.00 44.39 ? 238 ASP A OD2 1 ATOM 1660 N N . PHE A 1 266 ? -43.603 -3.996 44.935 1.00 36.21 ? 239 PHE A N 1 ATOM 1661 C CA . PHE A 1 266 ? -42.354 -3.243 44.794 1.00 34.91 ? 239 PHE A CA 1 ATOM 1662 C C . PHE A 1 266 ? -41.806 -3.342 43.377 1.00 33.26 ? 239 PHE A C 1 ATOM 1663 O O . PHE A 1 266 ? -42.166 -4.250 42.636 1.00 34.20 ? 239 PHE A O 1 ATOM 1664 C CB . PHE A 1 266 ? -41.317 -3.688 45.823 1.00 31.88 ? 239 PHE A CB 1 ATOM 1665 C CG . PHE A 1 266 ? -40.857 -5.117 45.680 1.00 33.16 ? 239 PHE A CG 1 ATOM 1666 C CD1 . PHE A 1 266 ? -39.890 -5.473 44.751 1.00 33.99 ? 239 PHE A CD1 1 ATOM 1667 C CD2 . PHE A 1 266 ? -41.354 -6.111 46.520 1.00 33.53 ? 239 PHE A CD2 1 ATOM 1668 C CE1 . PHE A 1 266 ? -39.430 -6.783 44.653 1.00 32.59 ? 239 PHE A CE1 1 ATOM 1669 C CE2 . PHE A 1 266 ? -40.911 -7.420 46.411 1.00 33.64 ? 239 PHE A CE2 1 ATOM 1670 C CZ . PHE A 1 266 ? -39.930 -7.756 45.494 1.00 31.81 ? 239 PHE A CZ 1 ATOM 1671 N N . SER A 1 267 ? -40.949 -2.391 43.026 1.00 33.93 ? 240 SER A N 1 ATOM 1672 C CA . SER A 1 267 ? -40.256 -2.396 41.759 1.00 34.83 ? 240 SER A CA 1 ATOM 1673 C C . SER A 1 267 ? -38.845 -1.853 41.927 1.00 32.66 ? 240 SER A C 1 ATOM 1674 O O . SER A 1 267 ? -38.660 -0.683 42.210 1.00 33.76 ? 240 SER A O 1 ATOM 1675 C CB . SER A 1 267 ? -40.998 -1.529 40.748 1.00 38.04 ? 240 SER A CB 1 ATOM 1676 O OG . SER A 1 267 ? -42.193 -2.135 40.305 1.00 47.54 ? 240 SER A OG 1 ATOM 1677 N N . GLU A 1 268 ? -37.850 -2.700 41.711 1.00 31.07 ? 241 GLU A N 1 ATOM 1678 C CA . GLU A 1 268 ? -36.465 -2.332 41.947 1.00 32.41 ? 241 GLU A CA 1 ATOM 1679 C C . GLU A 1 268 ? -35.637 -2.576 40.706 1.00 31.96 ? 241 GLU A C 1 ATOM 1680 O O . GLU A 1 268 ? -36.019 -3.386 39.825 1.00 33.33 ? 241 GLU A O 1 ATOM 1681 C CB . GLU A 1 268 ? -35.897 -3.145 43.111 1.00 35.85 ? 241 GLU A CB 1 ATOM 1682 C CG . GLU A 1 268 ? -36.583 -2.873 44.457 1.00 39.54 ? 241 GLU A CG 1 ATOM 1683 C CD . GLU A 1 268 ? -36.527 -1.407 44.889 1.00 42.29 ? 241 GLU A CD 1 ATOM 1684 O OE1 . GLU A 1 268 ? -37.516 -0.892 45.455 1.00 43.95 ? 241 GLU A OE1 1 ATOM 1685 O OE2 . GLU A 1 268 ? -35.498 -0.756 44.641 1.00 45.44 ? 241 GLU A OE2 1 ATOM 1686 N N . LEU A 1 269 ? -34.507 -1.884 40.635 1.00 28.96 ? 242 LEU A N 1 ATOM 1687 C CA . LEU A 1 269 ? -33.608 -2.007 39.504 1.00 30.31 ? 242 LEU A CA 1 ATOM 1688 C C . LEU A 1 269 ? -32.295 -2.556 39.961 1.00 31.51 ? 242 LEU A C 1 ATOM 1689 O O . LEU A 1 269 ? -31.876 -2.258 41.069 1.00 34.60 ? 242 LEU A O 1 ATOM 1690 C CB . LEU A 1 269 ? -33.395 -0.650 38.867 1.00 30.51 ? 242 LEU A CB 1 ATOM 1691 C CG . LEU A 1 269 ? -34.676 -0.028 38.335 1.00 34.11 ? 242 LEU A CG 1 ATOM 1692 C CD1 . LEU A 1 269 ? -34.427 1.426 37.964 1.00 35.56 ? 242 LEU A CD1 1 ATOM 1693 C CD2 . LEU A 1 269 ? -35.229 -0.804 37.137 1.00 32.97 ? 242 LEU A CD2 1 ATOM 1694 N N . ILE A 1 270 ? -31.651 -3.352 39.107 1.00 30.51 ? 243 ILE A N 1 ATOM 1695 C CA . ILE A 1 270 ? -30.333 -3.915 39.381 1.00 32.17 ? 243 ILE A CA 1 ATOM 1696 C C . ILE A 1 270 ? -29.433 -3.879 38.159 1.00 32.18 ? 243 ILE A C 1 ATOM 1697 O O . ILE A 1 270 ? -29.908 -3.716 37.041 1.00 30.53 ? 243 ILE A O 1 ATOM 1698 C CB . ILE A 1 270 ? -30.429 -5.410 39.782 1.00 34.29 ? 243 ILE A CB 1 ATOM 1699 C CG1 . ILE A 1 270 ? -31.150 -6.216 38.693 1.00 32.69 ? 243 ILE A CG1 1 ATOM 1700 C CG2 . ILE A 1 270 ? -31.127 -5.544 41.127 1.00 35.66 ? 243 ILE A CG2 1 ATOM 1701 C CD1 . ILE A 1 270 ? -31.185 -7.708 38.948 1.00 34.26 ? 243 ILE A CD1 1 ATOM 1702 N N . SER A 1 271 ? -28.137 -4.075 38.377 1.00 32.44 ? 244 SER A N 1 ATOM 1703 C CA . SER A 1 271 ? -27.226 -4.356 37.284 1.00 35.01 ? 244 SER A CA 1 ATOM 1704 C C . SER A 1 271 ? -25.977 -5.092 37.743 1.00 37.61 ? 244 SER A C 1 ATOM 1705 O O . SER A 1 271 ? -25.709 -5.248 38.939 1.00 36.90 ? 244 SER A O 1 ATOM 1706 C CB . SER A 1 271 ? -26.828 -3.094 36.518 1.00 39.01 ? 244 SER A CB 1 ATOM 1707 O OG . SER A 1 271 ? -25.607 -2.562 36.980 1.00 40.12 ? 244 SER A OG 1 ATOM 1708 N N . GLN A 1 272 ? -25.235 -5.560 36.751 1.00 34.71 ? 245 GLN A N 1 ATOM 1709 C CA . GLN A 1 272 ? -23.954 -6.187 36.954 1.00 34.88 ? 245 GLN A CA 1 ATOM 1710 C C . GLN A 1 272 ? -23.084 -5.326 37.832 1.00 35.39 ? 245 GLN A C 1 ATOM 1711 O O . GLN A 1 272 ? -22.327 -5.848 38.638 1.00 37.00 ? 245 GLN A O 1 ATOM 1712 C CB . GLN A 1 272 ? -23.268 -6.362 35.607 1.00 35.23 ? 245 GLN A CB 1 ATOM 1713 C CG . GLN A 1 272 ? -22.004 -7.182 35.686 1.00 38.65 ? 245 GLN A CG 1 ATOM 1714 C CD . GLN A 1 272 ? -21.400 -7.586 34.355 1.00 40.87 ? 245 GLN A CD 1 ATOM 1715 O OE1 . GLN A 1 272 ? -20.293 -8.112 34.337 1.00 42.03 ? 245 GLN A OE1 1 ATOM 1716 N NE2 . GLN A 1 272 ? -22.105 -7.348 33.245 1.00 40.50 ? 245 GLN A NE2 1 ATOM 1717 N N . TYR A 1 273 ? -23.187 -4.007 37.674 1.00 33.48 ? 246 TYR A N 1 ATOM 1718 C CA . TYR A 1 273 ? -22.274 -3.098 38.351 1.00 36.91 ? 246 TYR A CA 1 ATOM 1719 C C . TYR A 1 273 ? -22.861 -2.423 39.576 1.00 36.18 ? 246 TYR A C 1 ATOM 1720 O O . TYR A 1 273 ? -22.243 -1.528 40.114 1.00 38.49 ? 246 TYR A O 1 ATOM 1721 C CB . TYR A 1 273 ? -21.679 -2.090 37.338 1.00 36.68 ? 246 TYR A CB 1 ATOM 1722 C CG . TYR A 1 273 ? -21.008 -2.811 36.198 1.00 34.50 ? 246 TYR A CG 1 ATOM 1723 C CD1 . TYR A 1 273 ? -19.796 -3.464 36.389 1.00 36.12 ? 246 TYR A CD1 1 ATOM 1724 C CD2 . TYR A 1 273 ? -21.630 -2.926 34.941 1.00 37.98 ? 246 TYR A CD2 1 ATOM 1725 C CE1 . TYR A 1 273 ? -19.186 -4.157 35.355 1.00 34.90 ? 246 TYR A CE1 1 ATOM 1726 C CE2 . TYR A 1 273 ? -21.031 -3.616 33.889 1.00 34.42 ? 246 TYR A CE2 1 ATOM 1727 C CZ . TYR A 1 273 ? -19.807 -4.233 34.102 1.00 36.09 ? 246 TYR A CZ 1 ATOM 1728 O OH . TYR A 1 273 ? -19.198 -4.937 33.075 1.00 36.11 ? 246 TYR A OH 1 ATOM 1729 N N . SER A 1 274 ? -24.019 -2.877 40.064 1.00 37.76 ? 247 SER A N 1 ATOM 1730 C CA . SER A 1 274 ? -24.556 -2.364 41.330 1.00 36.16 ? 247 SER A CA 1 ATOM 1731 C C . SER A 1 274 ? -23.515 -2.522 42.455 1.00 39.40 ? 247 SER A C 1 ATOM 1732 O O . SER A 1 274 ? -22.937 -3.594 42.616 1.00 38.21 ? 247 SER A O 1 ATOM 1733 C CB . SER A 1 274 ? -25.820 -3.126 41.752 1.00 36.61 ? 247 SER A CB 1 ATOM 1734 O OG . SER A 1 274 ? -26.878 -2.994 40.825 1.00 38.42 ? 247 SER A OG 1 ATOM 1735 N N . ASP A 1 275 ? -23.323 -1.491 43.264 1.00 40.55 ? 248 ASP A N 1 ATOM 1736 C CA . ASP A 1 275 ? -22.467 -1.620 44.438 1.00 44.23 ? 248 ASP A CA 1 ATOM 1737 C C . ASP A 1 275 ? -23.188 -2.291 45.617 1.00 44.32 ? 248 ASP A C 1 ATOM 1738 O O . ASP A 1 275 ? -24.391 -2.596 45.556 1.00 40.03 ? 248 ASP A O 1 ATOM 1739 C CB . ASP A 1 275 ? -21.882 -0.263 44.834 1.00 46.72 ? 248 ASP A CB 1 ATOM 1740 C CG . ASP A 1 275 ? -22.927 0.726 45.281 1.00 48.40 ? 248 ASP A CG 1 ATOM 1741 O OD1 . ASP A 1 275 ? -23.951 0.321 45.885 1.00 48.68 ? 248 ASP A OD1 1 ATOM 1742 O OD2 . ASP A 1 275 ? -22.708 1.933 45.035 1.00 55.46 ? 248 ASP A OD2 1 ATOM 1743 N N . GLU A 1 276 ? -22.437 -2.545 46.685 1.00 45.00 ? 249 GLU A N 1 ATOM 1744 C CA . GLU A 1 276 ? -22.960 -3.254 47.854 1.00 48.87 ? 249 GLU A CA 1 ATOM 1745 C C . GLU A 1 276 ? -24.216 -2.628 48.465 1.00 44.63 ? 249 GLU A C 1 ATOM 1746 O O . GLU A 1 276 ? -25.121 -3.338 48.908 1.00 41.82 ? 249 GLU A O 1 ATOM 1747 C CB . GLU A 1 276 ? -21.892 -3.340 48.960 1.00 56.47 ? 249 GLU A CB 1 ATOM 1748 C CG . GLU A 1 276 ? -20.829 -4.396 48.728 1.00 65.34 ? 249 GLU A CG 1 ATOM 1749 C CD . GLU A 1 276 ? -20.107 -4.792 50.011 1.00 72.94 ? 249 GLU A CD 1 ATOM 1750 O OE1 . GLU A 1 276 ? -20.200 -4.049 51.016 1.00 74.08 ? 249 GLU A OE1 1 ATOM 1751 O OE2 . GLU A 1 276 ? -19.443 -5.853 50.008 1.00 77.39 ? 249 GLU A OE2 1 ATOM 1752 N N . GLU A 1 277 ? -24.243 -1.309 48.539 1.00 44.57 ? 250 GLU A N 1 ATOM 1753 C CA . GLU A 1 277 ? -25.391 -0.601 49.120 1.00 48.33 ? 250 GLU A CA 1 ATOM 1754 C C . GLU A 1 277 ? -26.633 -0.772 48.282 1.00 43.83 ? 250 GLU A C 1 ATOM 1755 O O . GLU A 1 277 ? -27.715 -0.933 48.813 1.00 43.61 ? 250 GLU A O 1 ATOM 1756 C CB . GLU A 1 277 ? -25.123 0.891 49.201 1.00 53.05 ? 250 GLU A CB 1 ATOM 1757 C CG . GLU A 1 277 ? -24.045 1.289 50.185 1.00 64.27 ? 250 GLU A CG 1 ATOM 1758 C CD . GLU A 1 277 ? -23.694 2.752 50.044 1.00 73.51 ? 250 GLU A CD 1 ATOM 1759 O OE1 . GLU A 1 277 ? -24.011 3.516 50.978 1.00 83.15 ? 250 GLU A OE1 1 ATOM 1760 O OE2 . GLU A 1 277 ? -23.136 3.136 48.983 1.00 78.92 ? 250 GLU A OE2 1 ATOM 1761 N N . GLU A 1 278 ? -26.463 -0.701 46.969 1.00 42.55 ? 251 GLU A N 1 ATOM 1762 C CA . GLU A 1 278 ? -27.578 -0.820 46.032 1.00 41.22 ? 251 GLU A CA 1 ATOM 1763 C C . GLU A 1 278 ? -28.176 -2.202 46.142 1.00 37.70 ? 251 GLU A C 1 ATOM 1764 O O . GLU A 1 278 ? -29.379 -2.341 46.263 1.00 38.78 ? 251 GLU A O 1 ATOM 1765 C CB . GLU A 1 278 ? -27.111 -0.532 44.602 1.00 42.67 ? 251 GLU A CB 1 ATOM 1766 C CG . GLU A 1 278 ? -26.751 0.937 44.411 1.00 46.69 ? 251 GLU A CG 1 ATOM 1767 C CD . GLU A 1 278 ? -26.007 1.248 43.114 1.00 47.90 ? 251 GLU A CD 1 ATOM 1768 O OE1 . GLU A 1 278 ? -25.052 0.522 42.713 1.00 44.16 ? 251 GLU A OE1 1 ATOM 1769 O OE2 . GLU A 1 278 ? -26.372 2.267 42.505 1.00 49.15 ? 251 GLU A OE2 1 ATOM 1770 N N . ILE A 1 279 ? -27.322 -3.215 46.156 1.00 37.99 ? 252 ILE A N 1 ATOM 1771 C CA . ILE A 1 279 ? -27.763 -4.599 46.298 1.00 39.65 ? 252 ILE A CA 1 ATOM 1772 C C . ILE A 1 279 ? -28.450 -4.811 47.628 1.00 40.95 ? 252 ILE A C 1 ATOM 1773 O O . ILE A 1 279 ? -29.488 -5.468 47.710 1.00 45.37 ? 252 ILE A O 1 ATOM 1774 C CB . ILE A 1 279 ? -26.574 -5.557 46.131 1.00 43.29 ? 252 ILE A CB 1 ATOM 1775 C CG1 . ILE A 1 279 ? -26.156 -5.575 44.661 1.00 47.10 ? 252 ILE A CG1 1 ATOM 1776 C CG2 . ILE A 1 279 ? -26.904 -6.983 46.569 1.00 41.88 ? 252 ILE A CG2 1 ATOM 1777 C CD1 . ILE A 1 279 ? -24.686 -5.881 44.449 1.00 51.17 ? 252 ILE A CD1 1 ATOM 1778 N N . GLN A 1 280 ? -27.873 -4.241 48.674 1.00 42.56 ? 253 GLN A N 1 ATOM 1779 C CA . GLN A 1 280 ? -28.393 -4.428 50.022 1.00 41.49 ? 253 GLN A CA 1 ATOM 1780 C C . GLN A 1 280 ? -29.789 -3.849 50.128 1.00 41.00 ? 253 GLN A C 1 ATOM 1781 O O . GLN A 1 280 ? -30.687 -4.439 50.746 1.00 39.22 ? 253 GLN A O 1 ATOM 1782 C CB . GLN A 1 280 ? -27.466 -3.747 51.026 1.00 43.65 ? 253 GLN A CB 1 ATOM 1783 C CG . GLN A 1 280 ? -27.900 -3.869 52.480 1.00 46.90 ? 253 GLN A CG 1 ATOM 1784 C CD . GLN A 1 280 ? -26.907 -3.209 53.443 1.00 54.31 ? 253 GLN A CD 1 ATOM 1785 O OE1 . GLN A 1 280 ? -25.871 -2.651 53.022 1.00 56.55 ? 253 GLN A OE1 1 ATOM 1786 N NE2 . GLN A 1 280 ? -27.197 -3.295 54.744 1.00 54.84 ? 253 GLN A NE2 1 ATOM 1787 N N . HIS A 1 281 ? -29.968 -2.680 49.524 1.00 40.11 ? 254 HIS A N 1 ATOM 1788 C CA . HIS A 1 281 ? -31.265 -2.029 49.508 1.00 39.23 ? 254 HIS A CA 1 ATOM 1789 C C . HIS A 1 281 ? -32.326 -2.921 48.849 1.00 39.43 ? 254 HIS A C 1 ATOM 1790 O O . HIS A 1 281 ? -33.438 -3.063 49.380 1.00 39.08 ? 254 HIS A O 1 ATOM 1791 C CB . HIS A 1 281 ? -31.196 -0.682 48.792 1.00 41.22 ? 254 HIS A CB 1 ATOM 1792 C CG . HIS A 1 281 ? -32.539 -0.099 48.518 1.00 43.53 ? 254 HIS A CG 1 ATOM 1793 N ND1 . HIS A 1 281 ? -33.283 0.526 49.491 1.00 45.82 ? 254 HIS A ND1 1 ATOM 1794 C CD2 . HIS A 1 281 ? -33.308 -0.113 47.403 1.00 43.78 ? 254 HIS A CD2 1 ATOM 1795 C CE1 . HIS A 1 281 ? -34.444 0.899 48.984 1.00 45.00 ? 254 HIS A CE1 1 ATOM 1796 N NE2 . HIS A 1 281 ? -34.488 0.514 47.721 1.00 45.68 ? 254 HIS A NE2 1 ATOM 1797 N N . VAL A 1 282 ? -31.985 -3.532 47.713 1.00 37.34 ? 255 VAL A N 1 ATOM 1798 C CA . VAL A 1 282 ? -32.956 -4.367 46.993 1.00 36.69 ? 255 VAL A CA 1 ATOM 1799 C C . VAL A 1 282 ? -33.296 -5.614 47.813 1.00 36.85 ? 255 VAL A C 1 ATOM 1800 O O . VAL A 1 282 ? -34.477 -5.974 47.946 1.00 34.12 ? 255 VAL A O 1 ATOM 1801 C CB . VAL A 1 282 ? -32.457 -4.783 45.594 1.00 35.47 ? 255 VAL A CB 1 ATOM 1802 C CG1 . VAL A 1 282 ? -33.454 -5.719 44.919 1.00 33.58 ? 255 VAL A CG1 1 ATOM 1803 C CG2 . VAL A 1 282 ? -32.254 -3.553 44.726 1.00 36.85 ? 255 VAL A CG2 1 ATOM 1804 N N . VAL A 1 283 ? -32.274 -6.229 48.409 1.00 36.93 ? 256 VAL A N 1 ATOM 1805 C CA . VAL A 1 283 ? -32.491 -7.392 49.285 1.00 38.76 ? 256 VAL A CA 1 ATOM 1806 C C . VAL A 1 283 ? -33.391 -7.046 50.479 1.00 39.07 ? 256 VAL A C 1 ATOM 1807 O O . VAL A 1 283 ? -34.294 -7.808 50.840 1.00 38.45 ? 256 VAL A O 1 ATOM 1808 C CB . VAL A 1 283 ? -31.171 -7.980 49.778 1.00 41.58 ? 256 VAL A CB 1 ATOM 1809 C CG1 . VAL A 1 283 ? -31.409 -9.071 50.817 1.00 43.83 ? 256 VAL A CG1 1 ATOM 1810 C CG2 . VAL A 1 283 ? -30.400 -8.565 48.606 1.00 42.81 ? 256 VAL A CG2 1 ATOM 1811 N N . GLU A 1 284 ? -33.175 -5.878 51.062 1.00 40.19 ? 257 GLU A N 1 ATOM 1812 C CA . GLU A 1 284 ? -34.045 -5.418 52.140 1.00 42.09 ? 257 GLU A CA 1 ATOM 1813 C C . GLU A 1 284 ? -35.489 -5.219 51.695 1.00 43.93 ? 257 GLU A C 1 ATOM 1814 O O . GLU A 1 284 ? -36.415 -5.584 52.431 1.00 45.98 ? 257 GLU A O 1 ATOM 1815 C CB . GLU A 1 284 ? -33.498 -4.143 52.763 1.00 43.71 ? 257 GLU A CB 1 ATOM 1816 C CG . GLU A 1 284 ? -32.288 -4.419 53.644 1.00 45.35 ? 257 GLU A CG 1 ATOM 1817 C CD . GLU A 1 284 ? -31.748 -3.168 54.304 1.00 50.82 ? 257 GLU A CD 1 ATOM 1818 O OE1 . GLU A 1 284 ? -32.518 -2.190 54.462 1.00 52.80 ? 257 GLU A OE1 1 ATOM 1819 O OE2 . GLU A 1 284 ? -30.552 -3.160 54.669 1.00 57.63 ? 257 GLU A OE2 1 ATOM 1820 N N . VAL A 1 285 ? -35.694 -4.647 50.508 1.00 41.81 ? 258 VAL A N 1 ATOM 1821 C CA . VAL A 1 285 ? -37.049 -4.502 49.972 1.00 39.10 ? 258 VAL A CA 1 ATOM 1822 C C . VAL A 1 285 ? -37.692 -5.893 49.860 1.00 39.28 ? 258 VAL A C 1 ATOM 1823 O O . VAL A 1 285 ? -38.853 -6.085 50.241 1.00 36.41 ? 258 VAL A O 1 ATOM 1824 C CB . VAL A 1 285 ? -37.074 -3.771 48.603 1.00 37.99 ? 258 VAL A CB 1 ATOM 1825 C CG1 . VAL A 1 285 ? -38.440 -3.862 47.954 1.00 36.60 ? 258 VAL A CG1 1 ATOM 1826 C CG2 . VAL A 1 285 ? -36.677 -2.304 48.752 1.00 36.57 ? 258 VAL A CG2 1 ATOM 1827 N N . ILE A 1 286 ? -36.945 -6.851 49.336 1.00 36.14 ? 259 ILE A N 1 ATOM 1828 C CA . ILE A 1 286 ? -37.459 -8.200 49.189 1.00 40.68 ? 259 ILE A CA 1 ATOM 1829 C C . ILE A 1 286 ? -37.782 -8.797 50.570 1.00 42.79 ? 259 ILE A C 1 ATOM 1830 O O . ILE A 1 286 ? -38.874 -9.323 50.775 1.00 42.90 ? 259 ILE A O 1 ATOM 1831 C CB . ILE A 1 286 ? -36.483 -9.115 48.412 1.00 40.30 ? 259 ILE A CB 1 ATOM 1832 C CG1 . ILE A 1 286 ? -36.308 -8.639 46.961 1.00 39.69 ? 259 ILE A CG1 1 ATOM 1833 C CG2 . ILE A 1 286 ? -36.998 -10.545 48.394 1.00 41.71 ? 259 ILE A CG2 1 ATOM 1834 C CD1 . ILE A 1 286 ? -35.118 -9.263 46.254 1.00 38.00 ? 259 ILE A CD1 1 ATOM 1835 N N . GLN A 1 287 ? -36.851 -8.664 51.518 1.00 45.61 ? 260 GLN A N 1 ATOM 1836 C CA . GLN A 1 287 ? -37.058 -9.154 52.889 1.00 45.57 ? 260 GLN A CA 1 ATOM 1837 C C . GLN A 1 287 ? -38.273 -8.547 53.574 1.00 45.79 ? 260 GLN A C 1 ATOM 1838 O O . GLN A 1 287 ? -39.012 -9.265 54.242 1.00 46.65 ? 260 GLN A O 1 ATOM 1839 C CB . GLN A 1 287 ? -35.823 -8.913 53.751 1.00 47.12 ? 260 GLN A CB 1 ATOM 1840 C CG . GLN A 1 287 ? -34.739 -9.956 53.542 1.00 49.41 ? 260 GLN A CG 1 ATOM 1841 C CD . GLN A 1 287 ? -33.493 -9.710 54.385 1.00 52.59 ? 260 GLN A CD 1 ATOM 1842 O OE1 . GLN A 1 287 ? -33.013 -8.583 54.503 1.00 55.47 ? 260 GLN A OE1 1 ATOM 1843 N NE2 . GLN A 1 287 ? -32.968 -10.772 54.981 1.00 55.84 ? 260 GLN A NE2 1 ATOM 1844 N N . ASN A 1 288 ? -38.492 -7.246 53.397 1.00 42.15 ? 261 ASN A N 1 ATOM 1845 C CA . ASN A 1 288 ? -39.598 -6.551 54.059 1.00 44.27 ? 261 ASN A CA 1 ATOM 1846 C C . ASN A 1 288 ? -40.952 -6.657 53.340 1.00 46.16 ? 261 ASN A C 1 ATOM 1847 O O . ASN A 1 288 ? -41.942 -6.140 53.832 1.00 51.10 ? 261 ASN A O 1 ATOM 1848 C CB . ASN A 1 288 ? -39.264 -5.065 54.263 1.00 45.88 ? 261 ASN A CB 1 ATOM 1849 C CG . ASN A 1 288 ? -38.009 -4.856 55.089 1.00 49.94 ? 261 ASN A CG 1 ATOM 1850 O OD1 . ASN A 1 288 ? -37.367 -5.812 55.516 1.00 50.35 ? 261 ASN A OD1 1 ATOM 1851 N ND2 . ASN A 1 288 ? -37.646 -3.603 55.304 1.00 58.36 ? 261 ASN A ND2 1 ATOM 1852 N N . SER A 1 289 ? -41.003 -7.313 52.188 1.00 42.41 ? 262 SER A N 1 ATOM 1853 C CA . SER A 1 289 ? -42.247 -7.431 51.430 1.00 42.10 ? 262 SER A CA 1 ATOM 1854 C C . SER A 1 289 ? -42.941 -8.756 51.729 1.00 39.77 ? 262 SER A C 1 ATOM 1855 O O . SER A 1 289 ? -42.282 -9.773 51.885 1.00 40.30 ? 262 SER A O 1 ATOM 1856 C CB . SER A 1 289 ? -41.942 -7.358 49.929 1.00 39.18 ? 262 SER A CB 1 ATOM 1857 O OG . SER A 1 289 ? -43.069 -7.683 49.151 1.00 38.29 ? 262 SER A OG 1 ATOM 1858 N N . THR A 1 290 ? -44.268 -8.737 51.755 1.00 38.99 ? 263 THR A N 1 ATOM 1859 C CA . THR A 1 290 ? -45.048 -9.964 51.825 1.00 42.67 ? 263 THR A CA 1 ATOM 1860 C C . THR A 1 290 ? -45.054 -10.756 50.511 1.00 44.23 ? 263 THR A C 1 ATOM 1861 O O . THR A 1 290 ? -45.461 -11.933 50.495 1.00 40.97 ? 263 THR A O 1 ATOM 1862 C CB . THR A 1 290 ? -46.522 -9.677 52.174 1.00 43.59 ? 263 THR A CB 1 ATOM 1863 O OG1 . THR A 1 290 ? -47.075 -8.778 51.206 1.00 48.15 ? 263 THR A OG1 1 ATOM 1864 C CG2 . THR A 1 290 ? -46.637 -9.060 53.550 1.00 46.92 ? 263 THR A CG2 1 ATOM 1865 N N . ALA A 1 291 ? -44.641 -10.116 49.414 1.00 41.90 ? 264 ALA A N 1 ATOM 1866 C CA . ALA A 1 291 ? -44.725 -10.733 48.092 1.00 44.45 ? 264 ALA A CA 1 ATOM 1867 C C . ALA A 1 291 ? -43.932 -12.029 48.031 1.00 43.50 ? 264 ALA A C 1 ATOM 1868 O O . ALA A 1 291 ? -42.813 -12.105 48.508 1.00 42.97 ? 264 ALA A O 1 ATOM 1869 C CB . ALA A 1 291 ? -44.239 -9.783 47.019 1.00 46.31 ? 264 ALA A CB 1 ATOM 1870 N N . LYS A 1 292 ? -44.556 -13.045 47.459 1.00 43.32 ? 265 LYS A N 1 ATOM 1871 C CA . LYS A 1 292 ? -43.951 -14.350 47.287 1.00 46.88 ? 265 LYS A CA 1 ATOM 1872 C C . LYS A 1 292 ? -43.505 -14.517 45.830 1.00 43.32 ? 265 LYS A C 1 ATOM 1873 O O . LYS A 1 292 ? -42.474 -15.124 45.539 1.00 41.24 ? 265 LYS A O 1 ATOM 1874 C CB . LYS A 1 292 ? -44.983 -15.415 47.654 1.00 52.48 ? 265 LYS A CB 1 ATOM 1875 C CG . LYS A 1 292 ? -44.414 -16.792 47.952 1.00 66.39 ? 265 LYS A CG 1 ATOM 1876 C CD . LYS A 1 292 ? -45.539 -17.835 48.009 1.00 71.36 ? 265 LYS A CD 1 ATOM 1877 C CE . LYS A 1 292 ? -45.283 -18.967 49.005 1.00 72.96 ? 265 LYS A CE 1 ATOM 1878 N NZ . LYS A 1 292 ? -44.107 -19.827 48.678 1.00 72.33 ? 265 LYS A NZ 1 ATOM 1879 N N . VAL A 1 293 ? -44.304 -13.981 44.921 1.00 38.52 ? 266 VAL A N 1 ATOM 1880 C CA . VAL A 1 293 ? -44.013 -14.062 43.520 1.00 38.71 ? 266 VAL A CA 1 ATOM 1881 C C . VAL A 1 293 ? -43.181 -12.838 43.123 1.00 40.05 ? 266 VAL A C 1 ATOM 1882 O O . VAL A 1 293 ? -43.616 -11.702 43.346 1.00 36.55 ? 266 VAL A O 1 ATOM 1883 C CB . VAL A 1 293 ? -45.311 -14.061 42.709 1.00 41.22 ? 266 VAL A CB 1 ATOM 1884 C CG1 . VAL A 1 293 ? -44.998 -14.156 41.227 1.00 41.39 ? 266 VAL A CG1 1 ATOM 1885 C CG2 . VAL A 1 293 ? -46.205 -15.221 43.140 1.00 46.50 ? 266 VAL A CG2 1 ATOM 1886 N N . ILE A 1 294 ? -42.004 -13.073 42.533 1.00 37.64 ? 267 ILE A N 1 ATOM 1887 C CA . ILE A 1 294 ? -41.168 -11.986 42.036 1.00 36.66 ? 267 ILE A CA 1 ATOM 1888 C C . ILE A 1 294 ? -40.849 -12.148 40.550 1.00 34.60 ? 267 ILE A C 1 ATOM 1889 O O . ILE A 1 294 ? -40.254 -13.148 40.125 1.00 34.74 ? 267 ILE A O 1 ATOM 1890 C CB . ILE A 1 294 ? -39.885 -11.843 42.869 1.00 36.87 ? 267 ILE A CB 1 ATOM 1891 C CG1 . ILE A 1 294 ? -40.269 -11.746 44.356 1.00 35.83 ? 267 ILE A CG1 1 ATOM 1892 C CG2 . ILE A 1 294 ? -39.094 -10.610 42.412 1.00 35.52 ? 267 ILE A CG2 1 ATOM 1893 C CD1 . ILE A 1 294 ? -39.110 -11.691 45.319 1.00 37.05 ? 267 ILE A CD1 1 ATOM 1894 N N . VAL A 1 295 ? -41.273 -11.153 39.779 1.00 30.74 ? 268 VAL A N 1 ATOM 1895 C CA . VAL A 1 295 ? -41.051 -11.120 38.350 1.00 31.15 ? 268 VAL A CA 1 ATOM 1896 C C . VAL A 1 295 ? -39.740 -10.399 38.060 1.00 31.75 ? 268 VAL A C 1 ATOM 1897 O O . VAL A 1 295 ? -39.565 -9.260 38.479 1.00 30.35 ? 268 VAL A O 1 ATOM 1898 C CB . VAL A 1 295 ? -42.185 -10.389 37.642 1.00 30.86 ? 268 VAL A CB 1 ATOM 1899 C CG1 . VAL A 1 295 ? -41.986 -10.433 36.141 1.00 31.38 ? 268 VAL A CG1 1 ATOM 1900 C CG2 . VAL A 1 295 ? -43.525 -11.023 38.010 1.00 32.52 ? 268 VAL A CG2 1 ATOM 1901 N N . VAL A 1 296 ? -38.827 -11.066 37.342 1.00 29.84 ? 269 VAL A N 1 ATOM 1902 C CA . VAL A 1 296 ? -37.479 -10.568 37.138 1.00 29.48 ? 269 VAL A CA 1 ATOM 1903 C C . VAL A 1 296 ? -37.134 -10.539 35.647 1.00 30.74 ? 269 VAL A C 1 ATOM 1904 O O . VAL A 1 296 ? -37.005 -11.580 34.988 1.00 28.59 ? 269 VAL A O 1 ATOM 1905 C CB . VAL A 1 296 ? -36.441 -11.421 37.887 1.00 31.03 ? 269 VAL A CB 1 ATOM 1906 C CG1 . VAL A 1 296 ? -35.040 -10.814 37.776 1.00 32.31 ? 269 VAL A CG1 1 ATOM 1907 C CG2 . VAL A 1 296 ? -36.835 -11.541 39.356 1.00 33.13 ? 269 VAL A CG2 1 ATOM 1908 N N . PHE A 1 297 ? -36.964 -9.329 35.135 1.00 28.91 ? 270 PHE A N 1 ATOM 1909 C CA . PHE A 1 297 ? -36.607 -9.129 33.750 1.00 27.99 ? 270 PHE A CA 1 ATOM 1910 C C . PHE A 1 297 ? -35.154 -8.680 33.715 1.00 28.11 ? 270 PHE A C 1 ATOM 1911 O O . PHE A 1 297 ? -34.862 -7.495 33.932 1.00 28.64 ? 270 PHE A O 1 ATOM 1912 C CB . PHE A 1 297 ? -37.530 -8.078 33.140 1.00 28.02 ? 270 PHE A CB 1 ATOM 1913 C CG . PHE A 1 297 ? -38.160 -8.531 31.867 1.00 28.23 ? 270 PHE A CG 1 ATOM 1914 C CD1 . PHE A 1 297 ? -37.407 -8.600 30.719 1.00 28.16 ? 270 PHE A CD1 1 ATOM 1915 C CD2 . PHE A 1 297 ? -39.493 -8.949 31.835 1.00 30.17 ? 270 PHE A CD2 1 ATOM 1916 C CE1 . PHE A 1 297 ? -37.969 -9.064 29.540 1.00 29.46 ? 270 PHE A CE1 1 ATOM 1917 C CE2 . PHE A 1 297 ? -40.069 -9.413 30.647 1.00 30.65 ? 270 PHE A CE2 1 ATOM 1918 C CZ . PHE A 1 297 ? -39.304 -9.468 29.501 1.00 30.01 ? 270 PHE A CZ 1 ATOM 1919 N N . SER A 1 298 ? -34.250 -9.617 33.433 1.00 26.40 ? 271 SER A N 1 ATOM 1920 C CA . SER A 1 298 ? -32.822 -9.346 33.498 1.00 27.24 ? 271 SER A CA 1 ATOM 1921 C C . SER A 1 298 ? -32.004 -10.415 32.774 1.00 28.12 ? 271 SER A C 1 ATOM 1922 O O . SER A 1 298 ? -32.435 -11.559 32.638 1.00 26.65 ? 271 SER A O 1 ATOM 1923 C CB . SER A 1 298 ? -32.369 -9.313 34.970 1.00 28.91 ? 271 SER A CB 1 ATOM 1924 O OG . SER A 1 298 ? -30.953 -9.073 35.098 1.00 30.83 ? 271 SER A OG 1 ATOM 1925 N N . SER A 1 299 ? -30.809 -10.033 32.328 1.00 28.36 ? 272 SER A N 1 ATOM 1926 C CA . SER A 1 299 ? -29.800 -11.005 31.921 1.00 30.04 ? 272 SER A CA 1 ATOM 1927 C C . SER A 1 299 ? -29.209 -11.658 33.175 1.00 30.92 ? 272 SER A C 1 ATOM 1928 O O . SER A 1 299 ? -29.357 -11.144 34.295 1.00 30.90 ? 272 SER A O 1 ATOM 1929 C CB . SER A 1 299 ? -28.687 -10.320 31.121 1.00 29.79 ? 272 SER A CB 1 ATOM 1930 O OG . SER A 1 299 ? -27.918 -9.464 31.964 1.00 32.72 ? 272 SER A OG 1 ATOM 1931 N N . GLY A 1 300 ? -28.537 -12.785 32.972 1.00 32.27 ? 273 GLY A N 1 ATOM 1932 C CA . GLY A 1 300 ? -27.820 -13.477 34.036 1.00 31.92 ? 273 GLY A CA 1 ATOM 1933 C C . GLY A 1 300 ? -26.781 -12.583 34.685 1.00 31.55 ? 273 GLY A C 1 ATOM 1934 O O . GLY A 1 300 ? -26.731 -12.486 35.899 1.00 33.73 ? 273 GLY A O 1 ATOM 1935 N N . PRO A 1 301 ? -25.937 -11.923 33.878 1.00 31.84 ? 274 PRO A N 1 ATOM 1936 C CA . PRO A 1 301 ? -24.871 -11.124 34.482 1.00 32.54 ? 274 PRO A CA 1 ATOM 1937 C C . PRO A 1 301 ? -25.395 -9.973 35.340 1.00 32.90 ? 274 PRO A C 1 ATOM 1938 O O . PRO A 1 301 ? -24.809 -9.660 36.382 1.00 32.23 ? 274 PRO A O 1 ATOM 1939 C CB . PRO A 1 301 ? -24.090 -10.608 33.270 1.00 31.78 ? 274 PRO A CB 1 ATOM 1940 C CG . PRO A 1 301 ? -24.292 -11.682 32.239 1.00 34.99 ? 274 PRO A CG 1 ATOM 1941 C CD . PRO A 1 301 ? -25.710 -12.150 32.442 1.00 33.52 ? 274 PRO A CD 1 ATOM 1942 N N . ASP A 1 302 ? -26.495 -9.362 34.921 1.00 31.08 ? 275 ASP A N 1 ATOM 1943 C CA . ASP A 1 302 ? -27.073 -8.270 35.692 1.00 32.96 ? 275 ASP A CA 1 ATOM 1944 C C . ASP A 1 302 ? -27.814 -8.742 36.938 1.00 33.01 ? 275 ASP A C 1 ATOM 1945 O O . ASP A 1 302 ? -28.021 -7.960 37.841 1.00 32.93 ? 275 ASP A O 1 ATOM 1946 C CB . ASP A 1 302 ? -28.016 -7.429 34.824 1.00 33.36 ? 275 ASP A CB 1 ATOM 1947 C CG . ASP A 1 302 ? -27.270 -6.563 33.824 1.00 33.87 ? 275 ASP A CG 1 ATOM 1948 O OD1 . ASP A 1 302 ? -26.333 -5.831 34.232 1.00 34.50 ? 275 ASP A OD1 1 ATOM 1949 O OD2 . ASP A 1 302 ? -27.636 -6.613 32.633 1.00 35.69 ? 275 ASP A OD2 1 ATOM 1950 N N . LEU A 1 303 ? -28.219 -10.008 36.966 1.00 35.49 ? 276 LEU A N 1 ATOM 1951 C CA . LEU A 1 303 ? -28.951 -10.572 38.097 1.00 37.33 ? 276 LEU A CA 1 ATOM 1952 C C . LEU A 1 303 ? -28.006 -11.195 39.145 1.00 37.34 ? 276 LEU A C 1 ATOM 1953 O O . LEU A 1 303 ? -28.330 -11.247 40.331 1.00 33.43 ? 276 LEU A O 1 ATOM 1954 C CB . LEU A 1 303 ? -29.924 -11.639 37.581 1.00 37.37 ? 276 LEU A CB 1 ATOM 1955 C CG . LEU A 1 303 ? -31.248 -12.003 38.263 1.00 41.90 ? 276 LEU A CG 1 ATOM 1956 C CD1 . LEU A 1 303 ? -31.678 -13.452 38.083 1.00 38.72 ? 276 LEU A CD1 1 ATOM 1957 C CD2 . LEU A 1 303 ? -31.234 -11.618 39.713 1.00 41.77 ? 276 LEU A CD2 1 ATOM 1958 N N . GLU A 1 304 ? -26.846 -11.654 38.699 1.00 37.17 ? 277 GLU A N 1 ATOM 1959 C CA . GLU A 1 304 ? -25.949 -12.483 39.521 1.00 41.97 ? 277 GLU A CA 1 ATOM 1960 C C . GLU A 1 304 ? -25.582 -11.895 40.890 1.00 41.59 ? 277 GLU A C 1 ATOM 1961 O O . GLU A 1 304 ? -25.669 -12.598 41.900 1.00 40.72 ? 277 GLU A O 1 ATOM 1962 C CB . GLU A 1 304 ? -24.677 -12.817 38.737 1.00 44.41 ? 277 GLU A CB 1 ATOM 1963 C CG . GLU A 1 304 ? -23.731 -13.759 39.461 1.00 51.95 ? 277 GLU A CG 1 ATOM 1964 C CD . GLU A 1 304 ? -22.459 -14.048 38.680 1.00 55.56 ? 277 GLU A CD 1 ATOM 1965 O OE1 . GLU A 1 304 ? -22.094 -13.261 37.779 1.00 54.03 ? 277 GLU A OE1 1 ATOM 1966 O OE2 . GLU A 1 304 ? -21.822 -15.078 38.973 1.00 61.11 ? 277 GLU A OE2 1 ATOM 1967 N N . PRO A 1 305 ? -25.177 -10.616 40.935 1.00 39.63 ? 278 PRO A N 1 ATOM 1968 C CA . PRO A 1 305 ? -24.819 -10.072 42.243 1.00 42.19 ? 278 PRO A CA 1 ATOM 1969 C C . PRO A 1 305 ? -26.011 -10.029 43.216 1.00 41.83 ? 278 PRO A C 1 ATOM 1970 O O . PRO A 1 305 ? -25.834 -10.268 44.410 1.00 41.76 ? 278 PRO A O 1 ATOM 1971 C CB . PRO A 1 305 ? -24.305 -8.662 41.919 1.00 42.38 ? 278 PRO A CB 1 ATOM 1972 C CG . PRO A 1 305 ? -23.942 -8.697 40.464 1.00 41.78 ? 278 PRO A CG 1 ATOM 1973 C CD . PRO A 1 305 ? -24.938 -9.636 39.856 1.00 41.88 ? 278 PRO A CD 1 ATOM 1974 N N . LEU A 1 306 ? -27.209 -9.755 42.716 1.00 37.97 ? 279 LEU A N 1 ATOM 1975 C CA . LEU A 1 306 ? -28.374 -9.766 43.574 1.00 37.75 ? 279 LEU A CA 1 ATOM 1976 C C . LEU A 1 306 ? -28.602 -11.185 44.128 1.00 38.26 ? 279 LEU A C 1 ATOM 1977 O O . LEU A 1 306 ? -28.847 -11.361 45.329 1.00 37.28 ? 279 LEU A O 1 ATOM 1978 C CB . LEU A 1 306 ? -29.638 -9.280 42.848 1.00 37.05 ? 279 LEU A CB 1 ATOM 1979 C CG . LEU A 1 306 ? -30.926 -9.467 43.668 1.00 36.37 ? 279 LEU A CG 1 ATOM 1980 C CD1 . LEU A 1 306 ? -30.832 -8.694 44.973 1.00 38.92 ? 279 LEU A CD1 1 ATOM 1981 C CD2 . LEU A 1 306 ? -32.165 -9.040 42.906 1.00 37.37 ? 279 LEU A CD2 1 ATOM 1982 N N . ILE A 1 307 ? -28.546 -12.182 43.253 1.00 34.76 ? 280 ILE A N 1 ATOM 1983 C CA . ILE A 1 307 ? -28.849 -13.537 43.651 1.00 37.77 ? 280 ILE A CA 1 ATOM 1984 C C . ILE A 1 307 ? -27.836 -14.048 44.676 1.00 39.18 ? 280 ILE A C 1 ATOM 1985 O O . ILE A 1 307 ? -28.216 -14.713 45.630 1.00 38.81 ? 280 ILE A O 1 ATOM 1986 C CB . ILE A 1 307 ? -28.958 -14.471 42.429 1.00 42.57 ? 280 ILE A CB 1 ATOM 1987 C CG1 . ILE A 1 307 ? -30.297 -14.260 41.721 1.00 45.65 ? 280 ILE A CG1 1 ATOM 1988 C CG2 . ILE A 1 307 ? -28.821 -15.935 42.820 1.00 46.67 ? 280 ILE A CG2 1 ATOM 1989 C CD1 . ILE A 1 307 ? -31.545 -14.695 42.469 1.00 46.12 ? 280 ILE A CD1 1 ATOM 1990 N N . LYS A 1 308 ? -26.565 -13.715 44.495 1.00 40.97 ? 281 LYS A N 1 ATOM 1991 C CA . LYS A 1 308 ? -25.555 -14.118 45.454 1.00 43.03 ? 281 LYS A CA 1 ATOM 1992 C C . LYS A 1 308 ? -25.911 -13.650 46.842 1.00 44.42 ? 281 LYS A C 1 ATOM 1993 O O . LYS A 1 308 ? -25.792 -14.403 47.794 1.00 46.39 ? 281 LYS A O 1 ATOM 1994 C CB . LYS A 1 308 ? -24.173 -13.597 45.071 1.00 40.57 ? 281 LYS A CB 1 ATOM 1995 C CG . LYS A 1 308 ? -23.571 -14.384 43.935 1.00 39.37 ? 281 LYS A CG 1 ATOM 1996 C CD . LYS A 1 308 ? -22.187 -13.882 43.597 1.00 39.62 ? 281 LYS A CD 1 ATOM 1997 C CE . LYS A 1 308 ? -21.569 -14.765 42.538 1.00 42.64 ? 281 LYS A CE 1 ATOM 1998 N NZ . LYS A 1 308 ? -20.316 -14.150 42.021 1.00 45.06 ? 281 LYS A NZ 1 ATOM 1999 N N . GLU A 1 309 ? -26.344 -12.408 46.963 1.00 46.04 ? 282 GLU A N 1 ATOM 2000 C CA . GLU A 1 309 ? -26.652 -11.858 48.272 1.00 44.85 ? 282 GLU A CA 1 ATOM 2001 C C . GLU A 1 309 ? -27.924 -12.481 48.829 1.00 47.51 ? 282 GLU A C 1 ATOM 2002 O O . GLU A 1 309 ? -28.011 -12.736 50.021 1.00 48.06 ? 282 GLU A O 1 ATOM 2003 C CB . GLU A 1 309 ? -26.766 -10.343 48.200 1.00 44.40 ? 282 GLU A CB 1 ATOM 2004 C CG . GLU A 1 309 ? -27.039 -9.668 49.540 1.00 49.62 ? 282 GLU A CG 1 ATOM 2005 C CD . GLU A 1 309 ? -25.908 -9.819 50.562 1.00 51.40 ? 282 GLU A CD 1 ATOM 2006 O OE1 . GLU A 1 309 ? -26.161 -9.560 51.763 1.00 53.73 ? 282 GLU A OE1 1 ATOM 2007 O OE2 . GLU A 1 309 ? -24.776 -10.209 50.187 1.00 49.56 ? 282 GLU A OE2 1 ATOM 2008 N N . ILE A 1 310 ? -28.898 -12.759 47.968 1.00 46.69 ? 283 ILE A N 1 ATOM 2009 C CA . ILE A 1 310 ? -30.130 -13.413 48.407 1.00 46.44 ? 283 ILE A CA 1 ATOM 2010 C C . ILE A 1 310 ? -29.840 -14.820 48.963 1.00 45.93 ? 283 ILE A C 1 ATOM 2011 O O . ILE A 1 310 ? -30.412 -15.250 49.962 1.00 42.69 ? 283 ILE A O 1 ATOM 2012 C CB . ILE A 1 310 ? -31.161 -13.479 47.267 1.00 47.53 ? 283 ILE A CB 1 ATOM 2013 C CG1 . ILE A 1 310 ? -31.708 -12.084 47.002 1.00 48.17 ? 283 ILE A CG1 1 ATOM 2014 C CG2 . ILE A 1 310 ? -32.329 -14.394 47.632 1.00 48.32 ? 283 ILE A CG2 1 ATOM 2015 C CD1 . ILE A 1 310 ? -32.574 -11.992 45.764 1.00 51.45 ? 283 ILE A CD1 1 ATOM 2016 N N . VAL A 1 311 ? -28.955 -15.527 48.288 1.00 48.33 ? 284 VAL A N 1 ATOM 2017 C CA . VAL A 1 311 ? -28.499 -16.818 48.745 1.00 51.21 ? 284 VAL A CA 1 ATOM 2018 C C . VAL A 1 311 ? -27.741 -16.679 50.071 1.00 51.64 ? 284 VAL A C 1 ATOM 2019 O O . VAL A 1 311 ? -28.007 -17.411 51.025 1.00 50.71 ? 284 VAL A O 1 ATOM 2020 C CB . VAL A 1 311 ? -27.634 -17.468 47.659 1.00 50.43 ? 284 VAL A CB 1 ATOM 2021 C CG1 . VAL A 1 311 ? -26.876 -18.670 48.200 1.00 52.26 ? 284 VAL A CG1 1 ATOM 2022 C CG2 . VAL A 1 311 ? -28.522 -17.881 46.501 1.00 49.70 ? 284 VAL A CG2 1 ATOM 2023 N N . ARG A 1 312 ? -26.825 -15.719 50.137 1.00 50.96 ? 285 ARG A N 1 ATOM 2024 C CA . ARG A 1 312 ? -26.081 -15.448 51.363 1.00 53.09 ? 285 ARG A CA 1 ATOM 2025 C C . ARG A 1 312 ? -27.034 -15.298 52.554 1.00 55.76 ? 285 ARG A C 1 ATOM 2026 O O . ARG A 1 312 ? -26.774 -15.837 53.622 1.00 57.00 ? 285 ARG A O 1 ATOM 2027 C CB . ARG A 1 312 ? -25.219 -14.196 51.217 1.00 53.61 ? 285 ARG A CB 1 ATOM 2028 C CG . ARG A 1 312 ? -23.807 -14.343 51.736 1.00 61.73 ? 285 ARG A CG 1 ATOM 2029 C CD . ARG A 1 312 ? -23.062 -13.011 51.802 1.00 67.71 ? 285 ARG A CD 1 ATOM 2030 N NE . ARG A 1 312 ? -23.818 -11.876 52.349 1.00 74.47 ? 285 ARG A NE 1 ATOM 2031 C CZ . ARG A 1 312 ? -23.942 -11.530 53.633 1.00 75.13 ? 285 ARG A CZ 1 ATOM 2032 N NH1 . ARG A 1 312 ? -24.661 -10.449 53.937 1.00 73.80 ? 285 ARG A NH1 1 ATOM 2033 N NH2 . ARG A 1 312 ? -23.383 -12.240 54.610 1.00 79.42 ? 285 ARG A NH2 1 ATOM 2034 N N . ARG A 1 313 ? -28.150 -14.604 52.363 1.00 54.41 ? 286 ARG A N 1 ATOM 2035 C CA . ARG A 1 313 ? -29.106 -14.391 53.444 1.00 54.55 ? 286 ARG A CA 1 ATOM 2036 C C . ARG A 1 313 ? -30.203 -15.440 53.533 1.00 56.32 ? 286 ARG A C 1 ATOM 2037 O O . ARG A 1 313 ? -31.106 -15.312 54.345 1.00 61.18 ? 286 ARG A O 1 ATOM 2038 C CB . ARG A 1 313 ? -29.751 -13.038 53.289 1.00 53.33 ? 286 ARG A CB 1 ATOM 2039 C CG . ARG A 1 313 ? -28.741 -11.922 53.194 1.00 56.63 ? 286 ARG A CG 1 ATOM 2040 C CD . ARG A 1 313 ? -29.389 -10.626 53.605 1.00 59.67 ? 286 ARG A CD 1 ATOM 2041 N NE . ARG A 1 313 ? -28.513 -9.466 53.447 1.00 58.89 ? 286 ARG A NE 1 ATOM 2042 C CZ . ARG A 1 313 ? -28.825 -8.247 53.873 1.00 60.40 ? 286 ARG A CZ 1 ATOM 2043 N NH1 . ARG A 1 313 ? -29.984 -8.024 54.488 1.00 57.54 ? 286 ARG A NH1 1 ATOM 2044 N NH2 . ARG A 1 313 ? -27.980 -7.246 53.683 1.00 66.09 ? 286 ARG A NH2 1 ATOM 2045 N N . ASN A 1 314 ? -30.138 -16.472 52.704 1.00 56.03 ? 287 ASN A N 1 ATOM 2046 C CA . ASN A 1 314 ? -31.041 -17.606 52.822 1.00 55.46 ? 287 ASN A CA 1 ATOM 2047 C C . ASN A 1 314 ? -32.516 -17.250 52.657 1.00 58.32 ? 287 ASN A C 1 ATOM 2048 O O . ASN A 1 314 ? -33.381 -17.739 53.396 1.00 52.86 ? 287 ASN A O 1 ATOM 2049 C CB . ASN A 1 314 ? -30.811 -18.300 54.170 1.00 59.50 ? 287 ASN A CB 1 ATOM 2050 C CG . ASN A 1 314 ? -31.285 -19.728 54.178 1.00 65.99 ? 287 ASN A CG 1 ATOM 2051 O OD1 . ASN A 1 314 ? -31.377 -20.370 53.124 1.00 64.95 ? 287 ASN A OD1 1 ATOM 2052 N ND2 . ASN A 1 314 ? -31.588 -20.243 55.378 1.00 76.69 ? 287 ASN A ND2 1 ATOM 2053 N N . ILE A 1 315 ? -32.814 -16.391 51.690 1.00 58.84 ? 288 ILE A N 1 ATOM 2054 C CA . ILE A 1 315 ? -34.199 -16.002 51.462 1.00 53.14 ? 288 ILE A CA 1 ATOM 2055 C C . ILE A 1 315 ? -34.893 -17.049 50.594 1.00 54.42 ? 288 ILE A C 1 ATOM 2056 O O . ILE A 1 315 ? -34.644 -17.141 49.389 1.00 54.54 ? 288 ILE A O 1 ATOM 2057 C CB . ILE A 1 315 ? -34.281 -14.602 50.859 1.00 53.34 ? 288 ILE A CB 1 ATOM 2058 C CG1 . ILE A 1 315 ? -33.759 -13.590 51.881 1.00 54.14 ? 288 ILE A CG1 1 ATOM 2059 C CG2 . ILE A 1 315 ? -35.715 -14.282 50.474 1.00 53.86 ? 288 ILE A CG2 1 ATOM 2060 C CD1 . ILE A 1 315 ? -33.300 -12.282 51.289 1.00 53.91 ? 288 ILE A CD1 1 ATOM 2061 N N . THR A 1 316 ? -35.789 -17.814 51.216 1.00 48.17 ? 289 THR A N 1 ATOM 2062 C CA . THR A 1 316 ? -36.340 -19.005 50.594 1.00 47.60 ? 289 THR A CA 1 ATOM 2063 C C . THR A 1 316 ? -37.809 -18.817 50.382 1.00 47.34 ? 289 THR A C 1 ATOM 2064 O O . THR A 1 316 ? -38.414 -17.872 50.872 1.00 49.03 ? 289 THR A O 1 ATOM 2065 C CB . THR A 1 316 ? -36.154 -20.294 51.449 1.00 52.25 ? 289 THR A CB 1 ATOM 2066 O OG1 . THR A 1 316 ? -36.909 -20.197 52.665 1.00 50.68 ? 289 THR A OG1 1 ATOM 2067 C CG2 . THR A 1 316 ? -34.681 -20.556 51.773 1.00 51.68 ? 289 THR A CG2 1 ATOM 2068 N N . GLY A 1 317 ? -38.381 -19.748 49.644 1.00 45.26 ? 290 GLY A N 1 ATOM 2069 C CA . GLY A 1 317 ? -39.815 -19.775 49.433 1.00 44.39 ? 290 GLY A CA 1 ATOM 2070 C C . GLY A 1 317 ? -40.363 -18.779 48.427 1.00 44.62 ? 290 GLY A C 1 ATOM 2071 O O . GLY A 1 317 ? -41.571 -18.652 48.312 1.00 42.57 ? 290 GLY A O 1 ATOM 2072 N N . LYS A 1 318 ? -39.500 -18.070 47.694 1.00 45.06 ? 291 LYS A N 1 ATOM 2073 C CA . LYS A 1 318 ? -39.982 -17.153 46.652 1.00 42.36 ? 291 LYS A CA 1 ATOM 2074 C C . LYS A 1 318 ? -40.300 -17.892 45.363 1.00 39.56 ? 291 LYS A C 1 ATOM 2075 O O . LYS A 1 318 ? -39.627 -18.843 44.996 1.00 38.99 ? 291 LYS A O 1 ATOM 2076 C CB . LYS A 1 318 ? -38.960 -16.047 46.369 1.00 42.29 ? 291 LYS A CB 1 ATOM 2077 C CG . LYS A 1 318 ? -38.645 -15.164 47.560 1.00 40.29 ? 291 LYS A CG 1 ATOM 2078 C CD . LYS A 1 318 ? -39.886 -14.502 48.142 1.00 38.70 ? 291 LYS A CD 1 ATOM 2079 C CE . LYS A 1 318 ? -39.537 -13.752 49.415 1.00 40.14 ? 291 LYS A CE 1 ATOM 2080 N NZ . LYS A 1 318 ? -40.759 -13.257 50.089 1.00 41.35 ? 291 LYS A NZ 1 ATOM 2081 N N . ILE A 1 319 ? -41.343 -17.453 44.687 1.00 38.24 ? 292 ILE A N 1 ATOM 2082 C CA . ILE A 1 319 ? -41.652 -17.954 43.358 1.00 38.27 ? 292 ILE A CA 1 ATOM 2083 C C . ILE A 1 319 ? -41.096 -16.956 42.331 1.00 39.86 ? 292 ILE A C 1 ATOM 2084 O O . ILE A 1 319 ? -41.647 -15.852 42.175 1.00 39.87 ? 292 ILE A O 1 ATOM 2085 C CB . ILE A 1 319 ? -43.172 -18.144 43.188 1.00 39.05 ? 292 ILE A CB 1 ATOM 2086 C CG1 . ILE A 1 319 ? -43.694 -19.229 44.160 1.00 38.79 ? 292 ILE A CG1 1 ATOM 2087 C CG2 . ILE A 1 319 ? -43.510 -18.537 41.760 1.00 38.43 ? 292 ILE A CG2 1 ATOM 2088 C CD1 . ILE A 1 319 ? -45.209 -19.329 44.228 1.00 40.18 ? 292 ILE A CD1 1 ATOM 2089 N N . TRP A 1 320 ? -40.004 -17.335 41.660 1.00 36.15 ? 293 TRP A N 1 ATOM 2090 C CA . TRP A 1 320 ? -39.349 -16.476 40.662 1.00 36.45 ? 293 TRP A CA 1 ATOM 2091 C C . TRP A 1 320 ? -39.923 -16.694 39.262 1.00 33.95 ? 293 TRP A C 1 ATOM 2092 O O . TRP A 1 320 ? -39.981 -17.821 38.800 1.00 35.12 ? 293 TRP A O 1 ATOM 2093 C CB . TRP A 1 320 ? -37.848 -16.752 40.623 1.00 37.32 ? 293 TRP A CB 1 ATOM 2094 C CG . TRP A 1 320 ? -37.181 -16.598 41.924 1.00 39.04 ? 293 TRP A CG 1 ATOM 2095 C CD1 . TRP A 1 320 ? -36.861 -17.590 42.803 1.00 42.61 ? 293 TRP A CD1 1 ATOM 2096 C CD2 . TRP A 1 320 ? -36.751 -15.381 42.522 1.00 41.63 ? 293 TRP A CD2 1 ATOM 2097 N NE1 . TRP A 1 320 ? -36.257 -17.064 43.917 1.00 43.16 ? 293 TRP A NE1 1 ATOM 2098 C CE2 . TRP A 1 320 ? -36.180 -15.708 43.774 1.00 42.14 ? 293 TRP A CE2 1 ATOM 2099 C CE3 . TRP A 1 320 ? -36.796 -14.040 42.130 1.00 43.98 ? 293 TRP A CE3 1 ATOM 2100 C CZ2 . TRP A 1 320 ? -35.658 -14.752 44.628 1.00 42.98 ? 293 TRP A CZ2 1 ATOM 2101 C CZ3 . TRP A 1 320 ? -36.265 -13.085 42.982 1.00 46.31 ? 293 TRP A CZ3 1 ATOM 2102 C CH2 . TRP A 1 320 ? -35.711 -13.448 44.221 1.00 47.91 ? 293 TRP A CH2 1 ATOM 2103 N N . LEU A 1 321 ? -40.398 -15.630 38.624 1.00 35.16 ? 294 LEU A N 1 ATOM 2104 C CA . LEU A 1 321 ? -40.774 -15.679 37.211 1.00 35.48 ? 294 LEU A CA 1 ATOM 2105 C C . LEU A 1 321 ? -39.646 -15.040 36.389 1.00 37.12 ? 294 LEU A C 1 ATOM 2106 O O . LEU A 1 321 ? -39.342 -13.846 36.558 1.00 35.72 ? 294 LEU A O 1 ATOM 2107 C CB . LEU A 1 321 ? -42.095 -14.984 36.914 1.00 38.58 ? 294 LEU A CB 1 ATOM 2108 C CG . LEU A 1 321 ? -43.346 -15.419 37.683 1.00 43.33 ? 294 LEU A CG 1 ATOM 2109 C CD1 . LEU A 1 321 ? -44.574 -14.765 37.055 1.00 43.72 ? 294 LEU A CD1 1 ATOM 2110 C CD2 . LEU A 1 321 ? -43.501 -16.933 37.679 1.00 45.82 ? 294 LEU A CD2 1 ATOM 2111 N N . ALA A 1 322 ? -39.049 -15.837 35.508 1.00 35.28 ? 295 ALA A N 1 ATOM 2112 C CA . ALA A 1 322 ? -37.765 -15.511 34.887 1.00 34.69 ? 295 ALA A CA 1 ATOM 2113 C C . ALA A 1 322 ? -37.921 -15.147 33.444 1.00 32.69 ? 295 ALA A C 1 ATOM 2114 O O . ALA A 1 322 ? -38.489 -15.921 32.667 1.00 33.76 ? 295 ALA A O 1 ATOM 2115 C CB . ALA A 1 322 ? -36.813 -16.697 34.987 1.00 35.10 ? 295 ALA A CB 1 ATOM 2116 N N . SER A 1 323 ? -37.424 -13.974 33.068 1.00 29.27 ? 296 SER A N 1 ATOM 2117 C CA . SER A 1 323 ? -37.359 -13.660 31.661 1.00 30.99 ? 296 SER A CA 1 ATOM 2118 C C . SER A 1 323 ? -36.314 -14.575 30.987 1.00 31.08 ? 296 SER A C 1 ATOM 2119 O O . SER A 1 323 ? -35.454 -15.173 31.631 1.00 31.04 ? 296 SER A O 1 ATOM 2120 C CB . SER A 1 323 ? -37.041 -12.176 31.412 1.00 31.03 ? 296 SER A CB 1 ATOM 2121 O OG . SER A 1 323 ? -35.699 -11.868 31.719 1.00 27.96 ? 296 SER A OG 1 ATOM 2122 N N . GLU A 1 324 ? -36.397 -14.630 29.677 1.00 31.93 ? 297 GLU A N 1 ATOM 2123 C CA . GLU A 1 324 ? -35.749 -15.629 28.859 1.00 33.75 ? 297 GLU A CA 1 ATOM 2124 C C . GLU A 1 324 ? -34.251 -15.515 28.942 1.00 32.85 ? 297 GLU A C 1 ATOM 2125 O O . GLU A 1 324 ? -33.543 -16.522 28.785 1.00 32.12 ? 297 GLU A O 1 ATOM 2126 C CB . GLU A 1 324 ? -36.228 -15.477 27.417 1.00 35.27 ? 297 GLU A CB 1 ATOM 2127 C CG . GLU A 1 324 ? -35.583 -16.425 26.423 1.00 42.42 ? 297 GLU A CG 1 ATOM 2128 C CD . GLU A 1 324 ? -34.289 -15.890 25.837 1.00 45.02 ? 297 GLU A CD 1 ATOM 2129 O OE1 . GLU A 1 324 ? -34.178 -14.642 25.742 1.00 52.32 ? 297 GLU A OE1 1 ATOM 2130 O OE2 . GLU A 1 324 ? -33.407 -16.708 25.454 1.00 46.60 ? 297 GLU A OE2 1 ATOM 2131 N N . ALA A 1 325 ? -33.756 -14.305 29.206 1.00 31.29 ? 298 ALA A N 1 ATOM 2132 C CA . ALA A 1 325 ? -32.311 -14.088 29.232 1.00 32.51 ? 298 ALA A CA 1 ATOM 2133 C C . ALA A 1 325 ? -31.669 -14.767 30.419 1.00 32.71 ? 298 ALA A C 1 ATOM 2134 O O . ALA A 1 325 ? -30.519 -15.150 30.328 1.00 36.39 ? 298 ALA A O 1 ATOM 2135 C CB . ALA A 1 325 ? -31.965 -12.606 29.200 1.00 32.00 ? 298 ALA A CB 1 ATOM 2136 N N . TRP A 1 326 ? -32.379 -14.906 31.542 1.00 33.41 ? 299 TRP A N 1 ATOM 2137 C CA . TRP A 1 326 ? -31.798 -15.626 32.689 1.00 33.41 ? 299 TRP A CA 1 ATOM 2138 C C . TRP A 1 326 ? -32.466 -16.951 33.035 1.00 32.74 ? 299 TRP A C 1 ATOM 2139 O O . TRP A 1 326 ? -31.917 -17.699 33.825 1.00 31.06 ? 299 TRP A O 1 ATOM 2140 C CB . TRP A 1 326 ? -31.716 -14.748 33.937 1.00 34.23 ? 299 TRP A CB 1 ATOM 2141 C CG . TRP A 1 326 ? -32.974 -14.523 34.716 1.00 32.74 ? 299 TRP A CG 1 ATOM 2142 C CD1 . TRP A 1 326 ? -33.885 -13.539 34.524 1.00 32.09 ? 299 TRP A CD1 1 ATOM 2143 C CD2 . TRP A 1 326 ? -33.409 -15.255 35.861 1.00 35.09 ? 299 TRP A CD2 1 ATOM 2144 N NE1 . TRP A 1 326 ? -34.870 -13.603 35.478 1.00 34.89 ? 299 TRP A NE1 1 ATOM 2145 C CE2 . TRP A 1 326 ? -34.605 -14.656 36.309 1.00 34.32 ? 299 TRP A CE2 1 ATOM 2146 C CE3 . TRP A 1 326 ? -32.903 -16.360 36.560 1.00 36.38 ? 299 TRP A CE3 1 ATOM 2147 C CZ2 . TRP A 1 326 ? -35.313 -15.128 37.411 1.00 35.41 ? 299 TRP A CZ2 1 ATOM 2148 C CZ3 . TRP A 1 326 ? -33.605 -16.827 37.661 1.00 36.13 ? 299 TRP A CZ3 1 ATOM 2149 C CH2 . TRP A 1 326 ? -34.800 -16.212 38.075 1.00 36.81 ? 299 TRP A CH2 1 ATOM 2150 N N . ALA A 1 327 ? -33.596 -17.261 32.408 1.00 34.51 ? 300 ALA A N 1 ATOM 2151 C CA . ALA A 1 327 ? -34.311 -18.515 32.690 1.00 36.14 ? 300 ALA A CA 1 ATOM 2152 C C . ALA A 1 327 ? -33.477 -19.763 32.352 1.00 39.16 ? 300 ALA A C 1 ATOM 2153 O O . ALA A 1 327 ? -33.795 -20.852 32.841 1.00 36.67 ? 300 ALA A O 1 ATOM 2154 C CB . ALA A 1 327 ? -35.633 -18.555 31.948 1.00 35.08 ? 300 ALA A CB 1 ATOM 2155 N N . SER A 1 328 ? -32.430 -19.598 31.530 1.00 37.05 ? 301 SER A N 1 ATOM 2156 C CA . SER A 1 328 ? -31.511 -20.698 31.220 1.00 39.60 ? 301 SER A CA 1 ATOM 2157 C C . SER A 1 328 ? -30.056 -20.342 31.504 1.00 40.61 ? 301 SER A C 1 ATOM 2158 O O . SER A 1 328 ? -29.175 -20.964 30.948 1.00 39.40 ? 301 SER A O 1 ATOM 2159 C CB . SER A 1 328 ? -31.615 -21.092 29.737 1.00 40.25 ? 301 SER A CB 1 ATOM 2160 O OG . SER A 1 328 ? -32.955 -21.359 29.383 1.00 44.37 ? 301 SER A OG 1 ATOM 2161 N N . SER A 1 329 ? -29.804 -19.342 32.345 1.00 38.57 ? 302 SER A N 1 ATOM 2162 C CA . SER A 1 329 ? -28.452 -18.828 32.514 1.00 39.30 ? 302 SER A CA 1 ATOM 2163 C C . SER A 1 329 ? -27.673 -19.664 33.516 1.00 40.87 ? 302 SER A C 1 ATOM 2164 O O . SER A 1 329 ? -28.113 -19.844 34.646 1.00 40.92 ? 302 SER A O 1 ATOM 2165 C CB . SER A 1 329 ? -28.483 -17.396 33.003 1.00 38.16 ? 302 SER A CB 1 ATOM 2166 O OG . SER A 1 329 ? -27.196 -17.016 33.455 1.00 38.01 ? 302 SER A OG 1 ATOM 2167 N N . SER A 1 330 ? -26.505 -20.132 33.097 1.00 41.16 ? 303 SER A N 1 ATOM 2168 C CA . SER A 1 330 ? -25.611 -20.940 33.934 1.00 37.29 ? 303 SER A CA 1 ATOM 2169 C C . SER A 1 330 ? -25.018 -20.153 35.103 1.00 38.77 ? 303 SER A C 1 ATOM 2170 O O . SER A 1 330 ? -24.550 -20.739 36.083 1.00 40.76 ? 303 SER A O 1 ATOM 2171 C CB . SER A 1 330 ? -24.482 -21.515 33.073 1.00 37.81 ? 303 SER A CB 1 ATOM 2172 O OG . SER A 1 330 ? -23.615 -20.479 32.626 1.00 39.67 ? 303 SER A OG 1 ATOM 2173 N N . LEU A 1 331 ? -25.056 -18.831 35.030 1.00 39.20 ? 304 LEU A N 1 ATOM 2174 C CA . LEU A 1 331 ? -24.637 -18.000 36.160 1.00 39.41 ? 304 LEU A CA 1 ATOM 2175 C C . LEU A 1 331 ? -25.603 -18.047 37.331 1.00 41.57 ? 304 LEU A C 1 ATOM 2176 O O . LEU A 1 331 ? -25.231 -17.782 38.475 1.00 41.43 ? 304 LEU A O 1 ATOM 2177 C CB . LEU A 1 331 ? -24.490 -16.549 35.715 1.00 41.20 ? 304 LEU A CB 1 ATOM 2178 C CG . LEU A 1 331 ? -23.427 -16.340 34.630 1.00 40.50 ? 304 LEU A CG 1 ATOM 2179 C CD1 . LEU A 1 331 ? -23.445 -14.887 34.169 1.00 39.67 ? 304 LEU A CD1 1 ATOM 2180 C CD2 . LEU A 1 331 ? -22.057 -16.717 35.178 1.00 38.51 ? 304 LEU A CD2 1 ATOM 2181 N N . ILE A 1 332 ? -26.857 -18.361 37.043 1.00 43.61 ? 305 ILE A N 1 ATOM 2182 C CA . ILE A 1 332 ? -27.890 -18.349 38.066 1.00 42.01 ? 305 ILE A CA 1 ATOM 2183 C C . ILE A 1 332 ? -28.343 -19.756 38.432 1.00 39.84 ? 305 ILE A C 1 ATOM 2184 O O . ILE A 1 332 ? -28.649 -20.016 39.585 1.00 38.71 ? 305 ILE A O 1 ATOM 2185 C CB . ILE A 1 332 ? -29.101 -17.526 37.598 1.00 41.00 ? 305 ILE A CB 1 ATOM 2186 C CG1 . ILE A 1 332 ? -28.644 -16.147 37.058 1.00 41.46 ? 305 ILE A CG1 1 ATOM 2187 C CG2 . ILE A 1 332 ? -30.116 -17.389 38.729 1.00 39.14 ? 305 ILE A CG2 1 ATOM 2188 C CD1 . ILE A 1 332 ? -27.985 -15.210 38.063 1.00 40.61 ? 305 ILE A CD1 1 ATOM 2189 N N . ALA A 1 333 ? -28.430 -20.643 37.444 1.00 42.16 ? 306 ALA A N 1 ATOM 2190 C CA . ALA A 1 333 ? -28.903 -22.003 37.671 1.00 43.66 ? 306 ALA A CA 1 ATOM 2191 C C . ALA A 1 333 ? -27.763 -22.852 38.213 1.00 46.03 ? 306 ALA A C 1 ATOM 2192 O O . ALA A 1 333 ? -27.252 -23.731 37.539 1.00 47.29 ? 306 ALA A O 1 ATOM 2193 C CB . ALA A 1 333 ? -29.456 -22.607 36.387 1.00 41.94 ? 306 ALA A CB 1 ATOM 2194 N N . MET A 1 334 ? -27.395 -22.590 39.454 1.00 50.78 ? 307 MET A N 1 ATOM 2195 C CA . MET A 1 334 ? -26.296 -23.286 40.101 1.00 53.10 ? 307 MET A CA 1 ATOM 2196 C C . MET A 1 334 ? -26.816 -24.039 41.317 1.00 53.39 ? 307 MET A C 1 ATOM 2197 O O . MET A 1 334 ? -27.576 -23.480 42.115 1.00 49.23 ? 307 MET A O 1 ATOM 2198 C CB . MET A 1 334 ? -25.228 -22.295 40.506 1.00 54.24 ? 307 MET A CB 1 ATOM 2199 C CG . MET A 1 334 ? -24.590 -21.641 39.296 1.00 58.52 ? 307 MET A CG 1 ATOM 2200 S SD . MET A 1 334 ? -22.960 -21.006 39.658 1.00 64.82 ? 307 MET A SD 1 ATOM 2201 C CE . MET A 1 334 ? -22.079 -22.554 39.781 1.00 66.71 ? 307 MET A CE 1 ATOM 2202 N N . PRO A 1 335 ? -26.414 -25.316 41.459 1.00 55.32 ? 308 PRO A N 1 ATOM 2203 C CA . PRO A 1 335 ? -26.911 -26.181 42.531 1.00 52.66 ? 308 PRO A CA 1 ATOM 2204 C C . PRO A 1 335 ? -26.882 -25.529 43.898 1.00 48.36 ? 308 PRO A C 1 ATOM 2205 O O . PRO A 1 335 ? -27.845 -25.632 44.641 1.00 48.06 ? 308 PRO A O 1 ATOM 2206 C CB . PRO A 1 335 ? -25.955 -27.378 42.481 1.00 54.45 ? 308 PRO A CB 1 ATOM 2207 C CG . PRO A 1 335 ? -25.561 -27.452 41.044 1.00 57.30 ? 308 PRO A CG 1 ATOM 2208 C CD . PRO A 1 335 ? -25.446 -26.026 40.596 1.00 56.68 ? 308 PRO A CD 1 ATOM 2209 N N . GLN A 1 336 ? -25.816 -24.819 44.222 1.00 48.46 ? 309 GLN A N 1 ATOM 2210 C CA . GLN A 1 336 ? -25.737 -24.206 45.545 1.00 50.07 ? 309 GLN A CA 1 ATOM 2211 C C . GLN A 1 336 ? -26.679 -23.012 45.759 1.00 48.04 ? 309 GLN A C 1 ATOM 2212 O O . GLN A 1 336 ? -26.741 -22.479 46.867 1.00 47.87 ? 309 GLN A O 1 ATOM 2213 C CB . GLN A 1 336 ? -24.299 -23.822 45.898 1.00 52.49 ? 309 GLN A CB 1 ATOM 2214 C CG . GLN A 1 336 ? -23.739 -22.622 45.163 1.00 56.63 ? 309 GLN A CG 1 ATOM 2215 C CD . GLN A 1 336 ? -23.083 -22.981 43.857 1.00 57.66 ? 309 GLN A CD 1 ATOM 2216 O OE1 . GLN A 1 336 ? -23.400 -24.000 43.235 1.00 58.37 ? 309 GLN A OE1 1 ATOM 2217 N NE2 . GLN A 1 336 ? -22.169 -22.130 43.419 1.00 64.29 ? 309 GLN A NE2 1 ATOM 2218 N N . TYR A 1 337 ? -27.388 -22.580 44.722 1.00 43.72 ? 310 TYR A N 1 ATOM 2219 C CA . TYR A 1 337 ? -28.405 -21.549 44.893 1.00 44.34 ? 310 TYR A CA 1 ATOM 2220 C C . TYR A 1 337 ? -29.805 -22.152 44.947 1.00 44.65 ? 310 TYR A C 1 ATOM 2221 O O . TYR A 1 337 ? -30.783 -21.417 45.038 1.00 47.31 ? 310 TYR A O 1 ATOM 2222 C CB . TYR A 1 337 ? -28.366 -20.550 43.734 1.00 43.82 ? 310 TYR A CB 1 ATOM 2223 C CG . TYR A 1 337 ? -27.048 -19.837 43.449 1.00 42.85 ? 310 TYR A CG 1 ATOM 2224 C CD1 . TYR A 1 337 ? -26.066 -19.661 44.429 1.00 43.05 ? 310 TYR A CD1 1 ATOM 2225 C CD2 . TYR A 1 337 ? -26.823 -19.273 42.197 1.00 42.59 ? 310 TYR A CD2 1 ATOM 2226 C CE1 . TYR A 1 337 ? -24.887 -18.968 44.145 1.00 41.79 ? 310 TYR A CE1 1 ATOM 2227 C CE2 . TYR A 1 337 ? -25.662 -18.577 41.904 1.00 42.26 ? 310 TYR A CE2 1 ATOM 2228 C CZ . TYR A 1 337 ? -24.701 -18.427 42.878 1.00 41.98 ? 310 TYR A CZ 1 ATOM 2229 O OH . TYR A 1 337 ? -23.568 -17.754 42.544 1.00 46.75 ? 310 TYR A OH 1 ATOM 2230 N N . PHE A 1 338 ? -29.917 -23.475 44.873 1.00 42.69 ? 311 PHE A N 1 ATOM 2231 C CA . PHE A 1 338 ? -31.204 -24.097 44.577 1.00 44.15 ? 311 PHE A CA 1 ATOM 2232 C C . PHE A 1 338 ? -32.245 -23.872 45.671 1.00 46.06 ? 311 PHE A C 1 ATOM 2233 O O . PHE A 1 338 ? -33.457 -23.858 45.406 1.00 41.84 ? 311 PHE A O 1 ATOM 2234 C CB . PHE A 1 338 ? -31.041 -25.587 44.302 1.00 44.57 ? 311 PHE A CB 1 ATOM 2235 C CG . PHE A 1 338 ? -32.261 -26.217 43.712 1.00 47.08 ? 311 PHE A CG 1 ATOM 2236 C CD1 . PHE A 1 338 ? -32.484 -26.157 42.348 1.00 49.40 ? 311 PHE A CD1 1 ATOM 2237 C CD2 . PHE A 1 338 ? -33.198 -26.845 44.515 1.00 48.40 ? 311 PHE A CD2 1 ATOM 2238 C CE1 . PHE A 1 338 ? -33.617 -26.716 41.790 1.00 50.25 ? 311 PHE A CE1 1 ATOM 2239 C CE2 . PHE A 1 338 ? -34.338 -27.411 43.965 1.00 50.82 ? 311 PHE A CE2 1 ATOM 2240 C CZ . PHE A 1 338 ? -34.544 -27.350 42.598 1.00 51.25 ? 311 PHE A CZ 1 ATOM 2241 N N . HIS A 1 339 ? -31.772 -23.693 46.894 1.00 48.93 ? 312 HIS A N 1 ATOM 2242 C CA . HIS A 1 339 ? -32.663 -23.443 48.025 1.00 51.71 ? 312 HIS A CA 1 ATOM 2243 C C . HIS A 1 339 ? -33.336 -22.081 47.933 1.00 51.27 ? 312 HIS A C 1 ATOM 2244 O O . HIS A 1 339 ? -34.365 -21.861 48.559 1.00 51.28 ? 312 HIS A O 1 ATOM 2245 C CB . HIS A 1 339 ? -31.931 -23.635 49.355 1.00 55.61 ? 312 HIS A CB 1 ATOM 2246 C CG . HIS A 1 339 ? -30.801 -22.676 49.587 1.00 63.42 ? 312 HIS A CG 1 ATOM 2247 N ND1 . HIS A 1 339 ? -29.589 -22.751 48.922 1.00 64.83 ? 312 HIS A ND1 1 ATOM 2248 C CD2 . HIS A 1 339 ? -30.688 -21.642 50.453 1.00 66.25 ? 312 HIS A CD2 1 ATOM 2249 C CE1 . HIS A 1 339 ? -28.789 -21.797 49.362 1.00 64.37 ? 312 HIS A CE1 1 ATOM 2250 N NE2 . HIS A 1 339 ? -29.433 -21.107 50.287 1.00 67.53 ? 312 HIS A NE2 1 ATOM 2251 N N . VAL A 1 340 ? -32.776 -21.182 47.122 1.00 51.84 ? 313 VAL A N 1 ATOM 2252 C CA . VAL A 1 340 ? -33.412 -19.888 46.823 1.00 48.58 ? 313 VAL A CA 1 ATOM 2253 C C . VAL A 1 340 ? -34.116 -19.884 45.477 1.00 46.68 ? 313 VAL A C 1 ATOM 2254 O O . VAL A 1 340 ? -35.198 -19.335 45.311 1.00 47.20 ? 313 VAL A O 1 ATOM 2255 C CB . VAL A 1 340 ? -32.355 -18.761 46.857 1.00 51.59 ? 313 VAL A CB 1 ATOM 2256 C CG1 . VAL A 1 340 ? -32.898 -17.454 46.297 1.00 49.16 ? 313 VAL A CG1 1 ATOM 2257 C CG2 . VAL A 1 340 ? -31.866 -18.568 48.285 1.00 51.13 ? 313 VAL A CG2 1 ATOM 2258 N N . VAL A 1 341 ? -33.500 -20.544 44.519 1.00 45.77 ? 314 VAL A N 1 ATOM 2259 C CA . VAL A 1 341 ? -33.810 -20.361 43.121 1.00 46.03 ? 314 VAL A CA 1 ATOM 2260 C C . VAL A 1 341 ? -34.604 -21.549 42.544 1.00 43.60 ? 314 VAL A C 1 ATOM 2261 O O . VAL A 1 341 ? -35.176 -21.471 41.458 1.00 40.35 ? 314 VAL A O 1 ATOM 2262 C CB . VAL A 1 341 ? -32.449 -20.071 42.429 1.00 46.26 ? 314 VAL A CB 1 ATOM 2263 C CG1 . VAL A 1 341 ? -32.036 -21.156 41.473 1.00 45.30 ? 314 VAL A CG1 1 ATOM 2264 C CG2 . VAL A 1 341 ? -32.415 -18.665 41.844 1.00 48.95 ? 314 VAL A CG2 1 ATOM 2265 N N . GLY A 1 342 ? -34.659 -22.645 43.294 1.00 41.63 ? 315 GLY A N 1 ATOM 2266 C CA . GLY A 1 342 ? -35.404 -23.825 42.900 1.00 39.24 ? 315 GLY A CA 1 ATOM 2267 C C . GLY A 1 342 ? -36.870 -23.515 42.648 1.00 38.55 ? 315 GLY A C 1 ATOM 2268 O O . GLY A 1 342 ? -37.491 -22.702 43.347 1.00 36.32 ? 315 GLY A O 1 ATOM 2269 N N . GLY A 1 343 ? -37.414 -24.160 41.628 1.00 34.54 ? 316 GLY A N 1 ATOM 2270 C CA . GLY A 1 343 ? -38.801 -23.970 41.255 1.00 33.96 ? 316 GLY A CA 1 ATOM 2271 C C . GLY A 1 343 ? -39.106 -22.740 40.410 1.00 36.60 ? 316 GLY A C 1 ATOM 2272 O O . GLY A 1 343 ? -40.273 -22.432 40.178 1.00 35.90 ? 316 GLY A O 1 ATOM 2273 N N . THR A 1 344 ? -38.077 -22.019 39.971 1.00 36.16 ? 317 THR A N 1 ATOM 2274 C CA . THR A 1 344 ? -38.237 -20.874 39.089 1.00 34.74 ? 317 THR A CA 1 ATOM 2275 C C . THR A 1 344 ? -39.046 -21.293 37.889 1.00 34.49 ? 317 THR A C 1 ATOM 2276 O O . THR A 1 344 ? -38.885 -22.401 37.401 1.00 34.06 ? 317 THR A O 1 ATOM 2277 C CB . THR A 1 344 ? -36.821 -20.374 38.633 1.00 35.14 ? 317 THR A CB 1 ATOM 2278 O OG1 . THR A 1 344 ? -36.180 -19.670 39.711 1.00 35.77 ? 317 THR A OG1 1 ATOM 2279 C CG2 . THR A 1 344 ? -36.875 -19.458 37.433 1.00 33.06 ? 317 THR A CG2 1 ATOM 2280 N N . ILE A 1 345 ? -39.944 -20.418 37.444 1.00 32.72 ? 318 ILE A N 1 ATOM 2281 C CA . ILE A 1 345 ? -40.716 -20.635 36.239 1.00 33.78 ? 318 ILE A CA 1 ATOM 2282 C C . ILE A 1 345 ? -40.275 -19.558 35.243 1.00 35.40 ? 318 ILE A C 1 ATOM 2283 O O . ILE A 1 345 ? -40.226 -18.381 35.588 1.00 35.59 ? 318 ILE A O 1 ATOM 2284 C CB . ILE A 1 345 ? -42.228 -20.492 36.491 1.00 34.74 ? 318 ILE A CB 1 ATOM 2285 C CG1 . ILE A 1 345 ? -42.740 -21.606 37.428 1.00 36.14 ? 318 ILE A CG1 1 ATOM 2286 C CG2 . ILE A 1 345 ? -42.973 -20.565 35.170 1.00 36.69 ? 318 ILE A CG2 1 ATOM 2287 C CD1 . ILE A 1 345 ? -44.085 -21.313 38.076 1.00 35.54 ? 318 ILE A CD1 1 ATOM 2288 N N . GLY A 1 346 ? -39.936 -19.963 34.025 1.00 35.40 ? 319 GLY A N 1 ATOM 2289 C CA . GLY A 1 346 ? -39.348 -19.052 33.049 1.00 35.93 ? 319 GLY A CA 1 ATOM 2290 C C . GLY A 1 346 ? -39.645 -19.387 31.606 1.00 36.39 ? 319 GLY A C 1 ATOM 2291 O O . GLY A 1 346 ? -40.399 -20.308 31.306 1.00 35.97 ? 319 GLY A O 1 ATOM 2292 N N . PHE A 1 347 ? -39.072 -18.599 30.711 1.00 35.49 ? 320 PHE A N 1 ATOM 2293 C CA . PHE A 1 347 ? -39.335 -18.724 29.293 1.00 34.77 ? 320 PHE A CA 1 ATOM 2294 C C . PHE A 1 347 ? -38.112 -19.171 28.544 1.00 35.37 ? 320 PHE A C 1 ATOM 2295 O O . PHE A 1 347 ? -36.996 -18.856 28.933 1.00 37.67 ? 320 PHE A O 1 ATOM 2296 C CB . PHE A 1 347 ? -39.872 -17.396 28.761 1.00 35.58 ? 320 PHE A CB 1 ATOM 2297 C CG . PHE A 1 347 ? -41.200 -17.060 29.343 1.00 35.14 ? 320 PHE A CG 1 ATOM 2298 C CD1 . PHE A 1 347 ? -42.355 -17.537 28.751 1.00 36.70 ? 320 PHE A CD1 1 ATOM 2299 C CD2 . PHE A 1 347 ? -41.300 -16.360 30.540 1.00 35.83 ? 320 PHE A CD2 1 ATOM 2300 C CE1 . PHE A 1 347 ? -43.587 -17.277 29.302 1.00 37.31 ? 320 PHE A CE1 1 ATOM 2301 C CE2 . PHE A 1 347 ? -42.540 -16.101 31.104 1.00 36.67 ? 320 PHE A CE2 1 ATOM 2302 C CZ . PHE A 1 347 ? -43.684 -16.549 30.472 1.00 37.10 ? 320 PHE A CZ 1 ATOM 2303 N N . ALA A 1 348 ? -38.353 -19.934 27.485 1.00 35.48 ? 321 ALA A N 1 ATOM 2304 C CA . ALA A 1 348 ? -37.309 -20.395 26.599 1.00 35.79 ? 321 ALA A CA 1 ATOM 2305 C C . ALA A 1 348 ? -37.764 -20.350 25.158 1.00 36.59 ? 321 ALA A C 1 ATOM 2306 O O . ALA A 1 348 ? -38.934 -20.633 24.853 1.00 40.20 ? 321 ALA A O 1 ATOM 2307 C CB . ALA A 1 348 ? -36.905 -21.795 26.977 1.00 38.26 ? 321 ALA A CB 1 ATOM 2308 N N . LEU A 1 349 ? -36.851 -19.937 24.278 1.00 39.63 ? 322 LEU A N 1 ATOM 2309 C CA . LEU A 1 349 ? -37.121 -19.798 22.838 1.00 41.73 ? 322 LEU A CA 1 ATOM 2310 C C . LEU A 1 349 ? -37.198 -21.209 22.250 1.00 43.34 ? 322 LEU A C 1 ATOM 2311 O O . LEU A 1 349 ? -36.686 -22.167 22.844 1.00 39.18 ? 322 LEU A O 1 ATOM 2312 C CB . LEU A 1 349 ? -35.986 -19.031 22.114 1.00 43.54 ? 322 LEU A CB 1 ATOM 2313 C CG . LEU A 1 349 ? -35.991 -17.514 21.822 1.00 46.66 ? 322 LEU A CG 1 ATOM 2314 C CD1 . LEU A 1 349 ? -37.005 -16.704 22.609 1.00 47.45 ? 322 LEU A CD1 1 ATOM 2315 C CD2 . LEU A 1 349 ? -34.579 -16.971 22.009 1.00 46.75 ? 322 LEU A CD2 1 ATOM 2316 N N . LYS A 1 350 ? -37.770 -21.320 21.062 1.00 42.25 ? 323 LYS A N 1 ATOM 2317 C CA . LYS A 1 350 ? -37.835 -22.607 20.343 1.00 49.14 ? 323 LYS A CA 1 ATOM 2318 C C . LYS A 1 350 ? -36.430 -23.027 19.894 1.00 47.93 ? 323 LYS A C 1 ATOM 2319 O O . LYS A 1 350 ? -35.679 -22.226 19.353 1.00 45.50 ? 323 LYS A O 1 ATOM 2320 C CB . LYS A 1 350 ? -38.752 -22.461 19.116 1.00 52.37 ? 323 LYS A CB 1 ATOM 2321 C CG . LYS A 1 350 ? -39.348 -23.742 18.511 1.00 61.95 ? 323 LYS A CG 1 ATOM 2322 C CD . LYS A 1 350 ? -39.207 -23.808 16.996 1.00 65.46 ? 323 LYS A CD 1 ATOM 2323 C CE . LYS A 1 350 ? -39.540 -22.467 16.300 1.00 69.67 ? 323 LYS A CE 1 ATOM 2324 N NZ . LYS A 1 350 ? -40.323 -22.556 15.025 1.00 74.83 ? 323 LYS A NZ 1 ATOM 2325 N N . ALA A 1 351 ? -36.056 -24.276 20.149 1.00 48.29 ? 324 ALA A N 1 ATOM 2326 C CA . ALA A 1 351 ? -34.777 -24.813 19.663 1.00 48.20 ? 324 ALA A CA 1 ATOM 2327 C C . ALA A 1 351 ? -34.785 -24.990 18.151 1.00 45.99 ? 324 ALA A C 1 ATOM 2328 O O . ALA A 1 351 ? -35.838 -25.158 17.542 1.00 46.22 ? 324 ALA A O 1 ATOM 2329 C CB . ALA A 1 351 ? -34.478 -26.145 20.338 1.00 52.06 ? 324 ALA A CB 1 ATOM 2330 N N . GLY A 1 352 ? -33.601 -24.938 17.557 1.00 44.71 ? 325 GLY A N 1 ATOM 2331 C CA . GLY A 1 352 ? -33.419 -25.205 16.140 1.00 45.72 ? 325 GLY A CA 1 ATOM 2332 C C . GLY A 1 352 ? -32.274 -26.179 15.976 1.00 52.14 ? 325 GLY A C 1 ATOM 2333 O O . GLY A 1 352 ? -31.526 -26.426 16.928 1.00 57.11 ? 325 GLY A O 1 ATOM 2334 N N . GLN A 1 353 ? -32.120 -26.754 14.788 1.00 52.75 ? 326 GLN A N 1 ATOM 2335 C CA . GLN A 1 353 ? -31.018 -27.686 14.562 1.00 53.64 ? 326 GLN A CA 1 ATOM 2336 C C . GLN A 1 353 ? -30.029 -27.171 13.548 1.00 47.45 ? 326 GLN A C 1 ATOM 2337 O O . GLN A 1 353 ? -30.390 -26.482 12.600 1.00 45.49 ? 326 GLN A O 1 ATOM 2338 C CB . GLN A 1 353 ? -31.561 -29.054 14.163 1.00 62.10 ? 326 GLN A CB 1 ATOM 2339 C CG . GLN A 1 353 ? -31.709 -29.966 15.370 1.00 67.90 ? 326 GLN A CG 1 ATOM 2340 C CD . GLN A 1 353 ? -33.032 -30.684 15.389 1.00 75.74 ? 326 GLN A CD 1 ATOM 2341 O OE1 . GLN A 1 353 ? -33.474 -31.219 14.363 1.00 81.94 ? 326 GLN A OE1 1 ATOM 2342 N NE2 . GLN A 1 353 ? -33.681 -30.706 16.557 1.00 75.77 ? 326 GLN A NE2 1 ATOM 2343 N N . ILE A 1 354 ? -28.770 -27.480 13.789 1.00 45.99 ? 327 ILE A N 1 ATOM 2344 C CA . ILE A 1 354 ? -27.704 -27.139 12.870 1.00 52.30 ? 327 ILE A CA 1 ATOM 2345 C C . ILE A 1 354 ? -26.830 -28.385 12.687 1.00 52.42 ? 327 ILE A C 1 ATOM 2346 O O . ILE A 1 354 ? -25.906 -28.624 13.477 1.00 52.86 ? 327 ILE A O 1 ATOM 2347 C CB . ILE A 1 354 ? -26.826 -25.974 13.381 1.00 51.73 ? 327 ILE A CB 1 ATOM 2348 C CG1 . ILE A 1 354 ? -27.679 -24.806 13.897 1.00 52.08 ? 327 ILE A CG1 1 ATOM 2349 C CG2 . ILE A 1 354 ? -25.908 -25.522 12.259 1.00 52.29 ? 327 ILE A CG2 1 ATOM 2350 C CD1 . ILE A 1 354 ? -26.853 -23.682 14.487 1.00 52.20 ? 327 ILE A CD1 1 ATOM 2351 N N . PRO A 1 355 ? -27.141 -29.199 11.664 1.00 55.98 ? 328 PRO A N 1 ATOM 2352 C CA . PRO A 1 355 ? -26.328 -30.397 11.402 1.00 53.69 ? 328 PRO A CA 1 ATOM 2353 C C . PRO A 1 355 ? -24.862 -30.061 11.162 1.00 49.70 ? 328 PRO A C 1 ATOM 2354 O O . PRO A 1 355 ? -24.552 -29.178 10.372 1.00 45.80 ? 328 PRO A O 1 ATOM 2355 C CB . PRO A 1 355 ? -26.967 -30.971 10.134 1.00 55.50 ? 328 PRO A CB 1 ATOM 2356 C CG . PRO A 1 355 ? -28.403 -30.553 10.223 1.00 56.47 ? 328 PRO A CG 1 ATOM 2357 C CD . PRO A 1 355 ? -28.364 -29.171 10.833 1.00 55.90 ? 328 PRO A CD 1 ATOM 2358 N N . GLY A 1 356 ? -23.978 -30.747 11.874 1.00 50.91 ? 329 GLY A N 1 ATOM 2359 C CA . GLY A 1 356 ? -22.541 -30.571 11.707 1.00 52.81 ? 329 GLY A CA 1 ATOM 2360 C C . GLY A 1 356 ? -21.930 -29.532 12.628 1.00 57.75 ? 329 GLY A C 1 ATOM 2361 O O . GLY A 1 356 ? -20.706 -29.358 12.633 1.00 60.17 ? 329 GLY A O 1 ATOM 2362 N N . PHE A 1 357 ? -22.756 -28.837 13.413 1.00 54.60 ? 330 PHE A N 1 ATOM 2363 C CA . PHE A 1 357 ? -22.242 -27.706 14.179 1.00 51.12 ? 330 PHE A CA 1 ATOM 2364 C C . PHE A 1 357 ? -21.428 -28.239 15.344 1.00 47.56 ? 330 PHE A C 1 ATOM 2365 O O . PHE A 1 357 ? -20.305 -27.819 15.566 1.00 46.75 ? 330 PHE A O 1 ATOM 2366 C CB . PHE A 1 357 ? -23.381 -26.786 14.651 1.00 51.23 ? 330 PHE A CB 1 ATOM 2367 C CG . PHE A 1 357 ? -22.924 -25.605 15.471 1.00 46.32 ? 330 PHE A CG 1 ATOM 2368 C CD1 . PHE A 1 357 ? -21.926 -24.762 15.012 1.00 43.94 ? 330 PHE A CD1 1 ATOM 2369 C CD2 . PHE A 1 357 ? -23.514 -25.328 16.692 1.00 46.01 ? 330 PHE A CD2 1 ATOM 2370 C CE1 . PHE A 1 357 ? -21.525 -23.669 15.755 1.00 46.19 ? 330 PHE A CE1 1 ATOM 2371 C CE2 . PHE A 1 357 ? -23.107 -24.238 17.446 1.00 46.01 ? 330 PHE A CE2 1 ATOM 2372 C CZ . PHE A 1 357 ? -22.117 -23.404 16.970 1.00 43.72 ? 330 PHE A CZ 1 ATOM 2373 N N . ARG A 1 358 ? -21.985 -29.196 16.068 1.00 49.93 ? 331 ARG A N 1 ATOM 2374 C CA . ARG A 1 358 ? -21.263 -29.811 17.179 1.00 53.58 ? 331 ARG A CA 1 ATOM 2375 C C . ARG A 1 358 ? -19.855 -30.308 16.791 1.00 58.12 ? 331 ARG A C 1 ATOM 2376 O O . ARG A 1 358 ? -18.887 -30.094 17.532 1.00 56.20 ? 331 ARG A O 1 ATOM 2377 C CB . ARG A 1 358 ? -22.079 -30.947 17.766 1.00 54.05 ? 331 ARG A CB 1 ATOM 2378 C CG . ARG A 1 358 ? -21.435 -31.549 18.994 1.00 56.32 ? 331 ARG A CG 1 ATOM 2379 C CD . ARG A 1 358 ? -22.398 -32.426 19.763 1.00 60.70 ? 331 ARG A CD 1 ATOM 2380 N NE . ARG A 1 358 ? -22.087 -32.309 21.176 1.00 64.93 ? 331 ARG A NE 1 ATOM 2381 C CZ . ARG A 1 358 ? -22.810 -31.643 22.075 1.00 68.92 ? 331 ARG A CZ 1 ATOM 2382 N NH1 . ARG A 1 358 ? -23.963 -31.054 21.761 1.00 67.50 ? 331 ARG A NH1 1 ATOM 2383 N NH2 . ARG A 1 358 ? -22.382 -31.601 23.325 1.00 74.91 ? 331 ARG A NH2 1 ATOM 2384 N N . GLU A 1 359 ? -19.745 -30.951 15.628 1.00 59.15 ? 332 GLU A N 1 ATOM 2385 C CA . GLU A 1 359 ? -18.457 -31.468 15.146 1.00 61.32 ? 332 GLU A CA 1 ATOM 2386 C C . GLU A 1 359 ? -17.513 -30.319 14.785 1.00 57.14 ? 332 GLU A C 1 ATOM 2387 O O . GLU A 1 359 ? -16.318 -30.387 15.054 1.00 58.56 ? 332 GLU A O 1 ATOM 2388 C CB . GLU A 1 359 ? -18.647 -32.406 13.945 1.00 63.17 ? 332 GLU A CB 1 ATOM 2389 C CG . GLU A 1 359 ? -19.591 -33.575 14.204 1.00 68.95 ? 332 GLU A CG 1 ATOM 2390 C CD . GLU A 1 359 ? -21.026 -33.306 13.747 1.00 75.74 ? 332 GLU A CD 1 ATOM 2391 O OE1 . GLU A 1 359 ? -21.427 -33.905 12.723 1.00 81.12 ? 332 GLU A OE1 1 ATOM 2392 O OE2 . GLU A 1 359 ? -21.752 -32.503 14.397 1.00 70.94 ? 332 GLU A OE2 1 ATOM 2393 N N . PHE A 1 360 ? -18.055 -29.267 14.178 1.00 55.80 ? 333 PHE A N 1 ATOM 2394 C CA . PHE A 1 360 ? -17.282 -28.058 13.901 1.00 53.99 ? 333 PHE A CA 1 ATOM 2395 C C . PHE A 1 360 ? -16.719 -27.458 15.191 1.00 54.03 ? 333 PHE A C 1 ATOM 2396 O O . PHE A 1 360 ? -15.542 -27.083 15.270 1.00 52.82 ? 333 PHE A O 1 ATOM 2397 C CB . PHE A 1 360 ? -18.170 -27.042 13.197 1.00 56.96 ? 333 PHE A CB 1 ATOM 2398 C CG . PHE A 1 360 ? -17.520 -25.718 12.998 1.00 59.47 ? 333 PHE A CG 1 ATOM 2399 C CD1 . PHE A 1 360 ? -16.646 -25.519 11.945 1.00 60.46 ? 333 PHE A CD1 1 ATOM 2400 C CD2 . PHE A 1 360 ? -17.786 -24.656 13.864 1.00 59.36 ? 333 PHE A CD2 1 ATOM 2401 C CE1 . PHE A 1 360 ? -16.034 -24.289 11.750 1.00 58.27 ? 333 PHE A CE1 1 ATOM 2402 C CE2 . PHE A 1 360 ? -17.184 -23.425 13.675 1.00 59.41 ? 333 PHE A CE2 1 ATOM 2403 C CZ . PHE A 1 360 ? -16.303 -23.244 12.618 1.00 59.40 ? 333 PHE A CZ 1 ATOM 2404 N N . LEU A 1 361 ? -17.580 -27.381 16.200 1.00 52.54 ? 334 LEU A N 1 ATOM 2405 C CA . LEU A 1 361 ? -17.217 -26.889 17.533 1.00 54.33 ? 334 LEU A CA 1 ATOM 2406 C C . LEU A 1 361 ? -16.030 -27.648 18.132 1.00 55.03 ? 334 LEU A C 1 ATOM 2407 O O . LEU A 1 361 ? -15.128 -27.048 18.716 1.00 53.74 ? 334 LEU A O 1 ATOM 2408 C CB . LEU A 1 361 ? -18.422 -27.015 18.489 1.00 52.88 ? 334 LEU A CB 1 ATOM 2409 C CG . LEU A 1 361 ? -19.274 -25.807 18.900 1.00 53.40 ? 334 LEU A CG 1 ATOM 2410 C CD1 . LEU A 1 361 ? -19.226 -24.667 17.899 1.00 53.84 ? 334 LEU A CD1 1 ATOM 2411 C CD2 . LEU A 1 361 ? -20.703 -26.223 19.202 1.00 51.75 ? 334 LEU A CD2 1 ATOM 2412 N N . LYS A 1 362 ? -16.037 -28.970 17.999 1.00 58.98 ? 335 LYS A N 1 ATOM 2413 C CA . LYS A 1 362 ? -14.940 -29.797 18.527 1.00 61.71 ? 335 LYS A CA 1 ATOM 2414 C C . LYS A 1 362 ? -13.618 -29.660 17.747 1.00 56.85 ? 335 LYS A C 1 ATOM 2415 O O . LYS A 1 362 ? -12.575 -30.055 18.253 1.00 59.28 ? 335 LYS A O 1 ATOM 2416 C CB . LYS A 1 362 ? -15.370 -31.261 18.616 1.00 63.37 ? 335 LYS A CB 1 ATOM 2417 C CG . LYS A 1 362 ? -16.368 -31.521 19.738 1.00 65.48 ? 335 LYS A CG 1 ATOM 2418 C CD . LYS A 1 362 ? -17.188 -32.773 19.492 1.00 63.72 ? 335 LYS A CD 1 ATOM 2419 C CE . LYS A 1 362 ? -17.963 -33.176 20.731 1.00 65.86 ? 335 LYS A CE 1 ATOM 2420 N NZ . LYS A 1 362 ? -18.750 -34.415 20.476 1.00 68.76 ? 335 LYS A NZ 1 ATOM 2421 N N . LYS A 1 363 ? -13.660 -29.088 16.544 1.00 54.35 ? 336 LYS A N 1 ATOM 2422 C CA . LYS A 1 363 ? -12.447 -28.851 15.758 1.00 53.50 ? 336 LYS A CA 1 ATOM 2423 C C . LYS A 1 363 ? -11.598 -27.658 16.213 1.00 55.86 ? 336 LYS A C 1 ATOM 2424 O O . LYS A 1 363 ? -10.495 -27.455 15.684 1.00 58.82 ? 336 LYS A O 1 ATOM 2425 C CB . LYS A 1 363 ? -12.803 -28.677 14.271 1.00 50.82 ? 336 LYS A CB 1 ATOM 2426 N N . VAL A 1 364 ? -12.072 -26.862 17.177 1.00 57.31 ? 337 VAL A N 1 ATOM 2427 C CA . VAL A 1 364 ? -11.337 -25.633 17.522 1.00 59.53 ? 337 VAL A CA 1 ATOM 2428 C C . VAL A 1 364 ? -9.932 -25.936 18.075 1.00 62.17 ? 337 VAL A C 1 ATOM 2429 O O . VAL A 1 364 ? -9.728 -26.903 18.816 1.00 61.57 ? 337 VAL A O 1 ATOM 2430 C CB . VAL A 1 364 ? -12.116 -24.674 18.472 1.00 57.85 ? 337 VAL A CB 1 ATOM 2431 C CG1 . VAL A 1 364 ? -12.364 -25.273 19.846 1.00 56.05 ? 337 VAL A CG1 1 ATOM 2432 C CG2 . VAL A 1 364 ? -11.367 -23.360 18.621 1.00 56.28 ? 337 VAL A CG2 1 ATOM 2433 N N . HIS A 1 365 ? -8.962 -25.106 17.701 1.00 65.77 ? 338 HIS A N 1 ATOM 2434 C CA . HIS A 1 365 ? -7.584 -25.306 18.145 1.00 68.32 ? 338 HIS A CA 1 ATOM 2435 C C . HIS A 1 365 ? -6.774 -24.026 18.114 1.00 62.32 ? 338 HIS A C 1 ATOM 2436 O O . HIS A 1 365 ? -6.825 -23.310 17.121 1.00 62.78 ? 338 HIS A O 1 ATOM 2437 C CB . HIS A 1 365 ? -6.884 -26.340 17.259 1.00 74.08 ? 338 HIS A CB 1 ATOM 2438 C CG . HIS A 1 365 ? -5.764 -27.040 17.951 1.00 78.85 ? 338 HIS A CG 1 ATOM 2439 N ND1 . HIS A 1 365 ? -5.977 -28.107 18.794 1.00 85.28 ? 338 HIS A ND1 1 ATOM 2440 C CD2 . HIS A 1 365 ? -4.433 -26.804 17.968 1.00 80.80 ? 338 HIS A CD2 1 ATOM 2441 C CE1 . HIS A 1 365 ? -4.823 -28.515 19.286 1.00 84.62 ? 338 HIS A CE1 1 ATOM 2442 N NE2 . HIS A 1 365 ? -3.869 -27.739 18.803 1.00 88.95 ? 338 HIS A NE2 1 ATOM 2443 N N . PRO A 1 366 ? -5.994 -23.757 19.179 1.00 60.26 ? 339 PRO A N 1 ATOM 2444 C CA . PRO A 1 366 ? -5.232 -22.511 19.232 1.00 61.73 ? 339 PRO A CA 1 ATOM 2445 C C . PRO A 1 366 ? -4.173 -22.385 18.141 1.00 65.74 ? 339 PRO A C 1 ATOM 2446 O O . PRO A 1 366 ? -3.857 -21.274 17.722 1.00 72.72 ? 339 PRO A O 1 ATOM 2447 C CB . PRO A 1 366 ? -4.579 -22.532 20.624 1.00 59.78 ? 339 PRO A CB 1 ATOM 2448 C CG . PRO A 1 366 ? -4.710 -23.920 21.131 1.00 58.03 ? 339 PRO A CG 1 ATOM 2449 C CD . PRO A 1 366 ? -5.875 -24.536 20.426 1.00 59.27 ? 339 PRO A CD 1 ATOM 2450 N N . ARG A 1 367 ? -3.616 -23.510 17.710 1.00 66.87 ? 340 ARG A N 1 ATOM 2451 C CA . ARG A 1 367 ? -2.660 -23.523 16.606 1.00 67.56 ? 340 ARG A CA 1 ATOM 2452 C C . ARG A 1 367 ? -3.394 -23.424 15.278 1.00 63.64 ? 340 ARG A C 1 ATOM 2453 O O . ARG A 1 367 ? -3.170 -22.490 14.515 1.00 67.86 ? 340 ARG A O 1 ATOM 2454 C CB . ARG A 1 367 ? -1.781 -24.788 16.646 1.00 68.01 ? 340 ARG A CB 1 ATOM 2455 N N . LYS A 1 368 ? -4.288 -24.372 15.018 1.00 63.32 ? 341 LYS A N 1 ATOM 2456 C CA . LYS A 1 368 ? -4.913 -24.517 13.701 1.00 67.12 ? 341 LYS A CA 1 ATOM 2457 C C . LYS A 1 368 ? -5.875 -23.381 13.325 1.00 69.81 ? 341 LYS A C 1 ATOM 2458 O O . LYS A 1 368 ? -5.951 -23.006 12.155 1.00 74.70 ? 341 LYS A O 1 ATOM 2459 C CB . LYS A 1 368 ? -5.637 -25.873 13.599 1.00 65.71 ? 341 LYS A CB 1 ATOM 2460 N N . SER A 1 369 ? -6.616 -22.848 14.299 1.00 70.69 ? 342 SER A N 1 ATOM 2461 C CA . SER A 1 369 ? -7.616 -21.800 14.030 1.00 64.30 ? 342 SER A CA 1 ATOM 2462 C C . SER A 1 369 ? -6.960 -20.439 13.795 1.00 64.76 ? 342 SER A C 1 ATOM 2463 O O . SER A 1 369 ? -7.034 -19.535 14.643 1.00 60.22 ? 342 SER A O 1 ATOM 2464 C CB . SER A 1 369 ? -8.634 -21.714 15.174 1.00 65.28 ? 342 SER A CB 1 ATOM 2465 O OG . SER A 1 369 ? -9.169 -22.991 15.493 1.00 66.64 ? 342 SER A OG 1 ATOM 2466 N N . VAL A 1 370 ? -6.341 -20.296 12.620 1.00 65.61 ? 343 VAL A N 1 ATOM 2467 C CA . VAL A 1 370 ? -5.592 -19.088 12.247 1.00 66.21 ? 343 VAL A CA 1 ATOM 2468 C C . VAL A 1 370 ? -6.462 -17.835 12.214 1.00 64.75 ? 343 VAL A C 1 ATOM 2469 O O . VAL A 1 370 ? -5.999 -16.747 12.554 1.00 65.06 ? 343 VAL A O 1 ATOM 2470 C CB . VAL A 1 370 ? -4.929 -19.233 10.855 1.00 64.33 ? 343 VAL A CB 1 ATOM 2471 N N . HIS A 1 371 ? -7.718 -17.995 11.807 1.00 63.50 ? 344 HIS A N 1 ATOM 2472 C CA . HIS A 1 371 ? -8.609 -16.864 11.604 1.00 62.68 ? 344 HIS A CA 1 ATOM 2473 C C . HIS A 1 371 ? -9.302 -16.389 12.891 1.00 61.43 ? 344 HIS A C 1 ATOM 2474 O O . HIS A 1 371 ? -9.689 -15.223 12.986 1.00 58.83 ? 344 HIS A O 1 ATOM 2475 C CB . HIS A 1 371 ? -9.639 -17.206 10.522 1.00 67.26 ? 344 HIS A CB 1 ATOM 2476 C CG . HIS A 1 371 ? -9.023 -17.528 9.192 1.00 72.14 ? 344 HIS A CG 1 ATOM 2477 N ND1 . HIS A 1 371 ? -8.348 -16.590 8.439 1.00 73.41 ? 344 HIS A ND1 1 ATOM 2478 C CD2 . HIS A 1 371 ? -8.980 -18.680 8.481 1.00 72.00 ? 344 HIS A CD2 1 ATOM 2479 C CE1 . HIS A 1 371 ? -7.921 -17.149 7.321 1.00 71.96 ? 344 HIS A CE1 1 ATOM 2480 N NE2 . HIS A 1 371 ? -8.294 -18.415 7.321 1.00 70.17 ? 344 HIS A NE2 1 ATOM 2481 N N . ASN A 1 372 ? -9.436 -17.277 13.875 1.00 53.19 ? 345 ASN A N 1 ATOM 2482 C CA . ASN A 1 372 ? -10.131 -16.969 15.110 1.00 49.26 ? 345 ASN A CA 1 ATOM 2483 C C . ASN A 1 372 ? -9.203 -16.701 16.284 1.00 47.98 ? 345 ASN A C 1 ATOM 2484 O O . ASN A 1 372 ? -8.872 -17.598 17.046 1.00 47.35 ? 345 ASN A O 1 ATOM 2485 C CB . ASN A 1 372 ? -11.082 -18.114 15.448 1.00 50.83 ? 345 ASN A CB 1 ATOM 2486 C CG . ASN A 1 372 ? -12.027 -17.791 16.604 1.00 49.74 ? 345 ASN A CG 1 ATOM 2487 O OD1 . ASN A 1 372 ? -11.847 -16.808 17.346 1.00 47.21 ? 345 ASN A OD1 1 ATOM 2488 N ND2 . ASN A 1 372 ? -13.043 -18.632 16.764 1.00 44.31 ? 345 ASN A ND2 1 ATOM 2489 N N . GLY A 1 373 ? -8.842 -15.435 16.459 1.00 48.47 ? 346 GLY A N 1 ATOM 2490 C CA . GLY A 1 373 ? -8.007 -15.003 17.588 1.00 50.12 ? 346 GLY A CA 1 ATOM 2491 C C . GLY A 1 373 ? -8.593 -15.080 18.996 1.00 51.46 ? 346 GLY A C 1 ATOM 2492 O O . GLY A 1 373 ? -7.945 -14.655 19.958 1.00 52.68 ? 346 GLY A O 1 ATOM 2493 N N . PHE A 1 374 ? -9.814 -15.594 19.136 1.00 48.97 ? 347 PHE A N 1 ATOM 2494 C CA . PHE A 1 374 ? -10.370 -15.854 20.460 1.00 46.28 ? 347 PHE A CA 1 ATOM 2495 C C . PHE A 1 374 ? -10.074 -17.291 20.886 1.00 48.92 ? 347 PHE A C 1 ATOM 2496 O O . PHE A 1 374 ? -10.315 -17.664 22.024 1.00 49.59 ? 347 PHE A O 1 ATOM 2497 C CB . PHE A 1 374 ? -11.892 -15.611 20.452 1.00 45.88 ? 347 PHE A CB 1 ATOM 2498 C CG . PHE A 1 374 ? -12.285 -14.185 20.158 1.00 42.40 ? 347 PHE A CG 1 ATOM 2499 C CD1 . PHE A 1 374 ? -12.090 -13.202 21.111 1.00 43.75 ? 347 PHE A CD1 1 ATOM 2500 C CD2 . PHE A 1 374 ? -12.853 -13.824 18.936 1.00 39.35 ? 347 PHE A CD2 1 ATOM 2501 C CE1 . PHE A 1 374 ? -12.436 -11.878 20.852 1.00 41.79 ? 347 PHE A CE1 1 ATOM 2502 C CE2 . PHE A 1 374 ? -13.199 -12.508 18.669 1.00 38.79 ? 347 PHE A CE2 1 ATOM 2503 C CZ . PHE A 1 374 ? -12.995 -11.533 19.632 1.00 39.98 ? 347 PHE A CZ 1 ATOM 2504 N N . ALA A 1 375 ? -9.600 -18.115 19.960 1.00 52.18 ? 348 ALA A N 1 ATOM 2505 C CA . ALA A 1 375 ? -9.366 -19.533 20.243 1.00 51.82 ? 348 ALA A CA 1 ATOM 2506 C C . ALA A 1 375 ? -8.274 -19.728 21.302 1.00 48.21 ? 348 ALA A C 1 ATOM 2507 O O . ALA A 1 375 ? -8.370 -20.622 22.146 1.00 46.60 ? 348 ALA A O 1 ATOM 2508 C CB . ALA A 1 375 ? -9.024 -20.276 18.953 1.00 54.23 ? 348 ALA A CB 1 ATOM 2509 N N . LYS A 1 376 ? -7.257 -18.874 21.270 1.00 49.46 ? 349 LYS A N 1 ATOM 2510 C CA . LYS A 1 376 ? -6.189 -18.926 22.266 1.00 50.29 ? 349 LYS A CA 1 ATOM 2511 C C . LYS A 1 376 ? -6.753 -18.855 23.671 1.00 53.62 ? 349 LYS A C 1 ATOM 2512 O O . LYS A 1 376 ? -6.608 -19.806 24.463 1.00 55.19 ? 349 LYS A O 1 ATOM 2513 C CB . LYS A 1 376 ? -5.173 -17.807 22.065 1.00 50.02 ? 349 LYS A CB 1 ATOM 2514 N N . GLU A 1 377 ? -7.414 -17.742 23.990 1.00 51.14 ? 350 GLU A N 1 ATOM 2515 C CA . GLU A 1 377 ? -7.922 -17.556 25.348 1.00 48.51 ? 350 GLU A CA 1 ATOM 2516 C C . GLU A 1 377 ? -8.961 -18.612 25.684 1.00 47.83 ? 350 GLU A C 1 ATOM 2517 O O . GLU A 1 377 ? -9.041 -19.068 26.835 1.00 45.26 ? 350 GLU A O 1 ATOM 2518 C CB . GLU A 1 377 ? -8.509 -16.153 25.546 1.00 50.86 ? 350 GLU A CB 1 ATOM 2519 C CG . GLU A 1 377 ? -8.964 -15.892 26.976 1.00 53.46 ? 350 GLU A CG 1 ATOM 2520 C CD . GLU A 1 377 ? -9.591 -14.525 27.175 1.00 57.03 ? 350 GLU A CD 1 ATOM 2521 O OE1 . GLU A 1 377 ? -9.744 -13.778 26.182 1.00 59.92 ? 350 GLU A OE1 1 ATOM 2522 O OE2 . GLU A 1 377 ? -9.953 -14.209 28.333 1.00 55.68 ? 350 GLU A OE2 1 ATOM 2523 N N . PHE A 1 378 ? -9.755 -19.005 24.688 1.00 47.66 ? 351 PHE A N 1 ATOM 2524 C CA . PHE A 1 378 ? -10.715 -20.088 24.881 1.00 47.94 ? 351 PHE A CA 1 ATOM 2525 C C . PHE A 1 378 ? -10.014 -21.320 25.441 1.00 48.22 ? 351 PHE A C 1 ATOM 2526 O O . PHE A 1 378 ? -10.526 -21.982 26.340 1.00 51.28 ? 351 PHE A O 1 ATOM 2527 C CB . PHE A 1 378 ? -11.417 -20.465 23.567 1.00 46.18 ? 351 PHE A CB 1 ATOM 2528 C CG . PHE A 1 378 ? -12.114 -21.788 23.635 1.00 49.77 ? 351 PHE A CG 1 ATOM 2529 C CD1 . PHE A 1 378 ? -13.347 -21.905 24.258 1.00 51.31 ? 351 PHE A CD1 1 ATOM 2530 C CD2 . PHE A 1 378 ? -11.523 -22.931 23.117 1.00 54.47 ? 351 PHE A CD2 1 ATOM 2531 C CE1 . PHE A 1 378 ? -13.993 -23.132 24.345 1.00 51.53 ? 351 PHE A CE1 1 ATOM 2532 C CE2 . PHE A 1 378 ? -12.160 -24.162 23.206 1.00 54.87 ? 351 PHE A CE2 1 ATOM 2533 C CZ . PHE A 1 378 ? -13.395 -24.262 23.822 1.00 53.51 ? 351 PHE A CZ 1 ATOM 2534 N N . TRP A 1 379 ? -8.850 -21.629 24.884 1.00 49.66 ? 352 TRP A N 1 ATOM 2535 C CA . TRP A 1 379 ? -8.108 -22.843 25.238 1.00 54.95 ? 352 TRP A CA 1 ATOM 2536 C C . TRP A 1 379 ? -7.593 -22.752 26.663 1.00 54.45 ? 352 TRP A C 1 ATOM 2537 O O . TRP A 1 379 ? -7.829 -23.629 27.500 1.00 51.22 ? 352 TRP A O 1 ATOM 2538 C CB . TRP A 1 379 ? -6.943 -23.036 24.262 1.00 60.25 ? 352 TRP A CB 1 ATOM 2539 C CG . TRP A 1 379 ? -6.487 -24.452 24.173 1.00 66.72 ? 352 TRP A CG 1 ATOM 2540 C CD1 . TRP A 1 379 ? -5.382 -24.996 24.757 1.00 65.10 ? 352 TRP A CD1 1 ATOM 2541 C CD2 . TRP A 1 379 ? -7.135 -25.513 23.460 1.00 69.24 ? 352 TRP A CD2 1 ATOM 2542 N NE1 . TRP A 1 379 ? -5.304 -26.329 24.460 1.00 65.81 ? 352 TRP A NE1 1 ATOM 2543 C CE2 . TRP A 1 379 ? -6.362 -26.675 23.659 1.00 67.93 ? 352 TRP A CE2 1 ATOM 2544 C CE3 . TRP A 1 379 ? -8.295 -25.593 22.667 1.00 64.52 ? 352 TRP A CE3 1 ATOM 2545 C CZ2 . TRP A 1 379 ? -6.713 -27.915 23.103 1.00 66.05 ? 352 TRP A CZ2 1 ATOM 2546 C CZ3 . TRP A 1 379 ? -8.639 -26.819 22.111 1.00 64.99 ? 352 TRP A CZ3 1 ATOM 2547 C CH2 . TRP A 1 379 ? -7.848 -27.965 22.331 1.00 65.22 ? 352 TRP A CH2 1 ATOM 2548 N N . GLU A 1 380 ? -6.936 -21.636 26.933 1.00 53.55 ? 353 GLU A N 1 ATOM 2549 C CA . GLU A 1 380 ? -6.406 -21.340 28.250 1.00 55.55 ? 353 GLU A CA 1 ATOM 2550 C C . GLU A 1 380 ? -7.468 -21.366 29.345 1.00 58.09 ? 353 GLU A C 1 ATOM 2551 O O . GLU A 1 380 ? -7.224 -21.862 30.440 1.00 53.82 ? 353 GLU A O 1 ATOM 2552 C CB . GLU A 1 380 ? -5.719 -19.979 28.208 1.00 60.62 ? 353 GLU A CB 1 ATOM 2553 C CG . GLU A 1 380 ? -4.479 -19.992 27.329 1.00 63.84 ? 353 GLU A CG 1 ATOM 2554 C CD . GLU A 1 380 ? -3.724 -18.686 27.349 1.00 68.75 ? 353 GLU A CD 1 ATOM 2555 O OE1 . GLU A 1 380 ? -4.327 -17.657 27.720 1.00 72.47 ? 353 GLU A OE1 1 ATOM 2556 O OE2 . GLU A 1 380 ? -2.526 -18.694 26.986 1.00 72.19 ? 353 GLU A OE2 1 ATOM 2557 N N . GLU A 1 381 ? -8.643 -20.823 29.051 1.00 57.51 ? 354 GLU A N 1 ATOM 2558 C CA . GLU A 1 381 ? -9.715 -20.807 30.024 1.00 56.80 ? 354 GLU A CA 1 ATOM 2559 C C . GLU A 1 381 ? -10.306 -22.187 30.210 1.00 55.95 ? 354 GLU A C 1 ATOM 2560 O O . GLU A 1 381 ? -10.625 -22.569 31.328 1.00 56.88 ? 354 GLU A O 1 ATOM 2561 C CB . GLU A 1 381 ? -10.796 -19.799 29.618 1.00 58.12 ? 354 GLU A CB 1 ATOM 2562 C CG . GLU A 1 381 ? -10.342 -18.368 29.848 1.00 58.26 ? 354 GLU A CG 1 ATOM 2563 C CD . GLU A 1 381 ? -9.891 -18.107 31.285 1.00 62.79 ? 354 GLU A CD 1 ATOM 2564 O OE1 . GLU A 1 381 ? -10.637 -18.412 32.250 1.00 68.24 ? 354 GLU A OE1 1 ATOM 2565 O OE2 . GLU A 1 381 ? -8.758 -17.608 31.458 1.00 60.96 ? 354 GLU A OE2 1 ATOM 2566 N N . THR A 1 382 ? -10.442 -22.939 29.124 1.00 54.18 ? 355 THR A N 1 ATOM 2567 C CA . THR A 1 382 ? -11.048 -24.272 29.203 1.00 54.28 ? 355 THR A CA 1 ATOM 2568 C C . THR A 1 382 ? -10.170 -25.222 30.038 1.00 57.23 ? 355 THR A C 1 ATOM 2569 O O . THR A 1 382 ? -10.661 -25.953 30.893 1.00 57.51 ? 355 THR A O 1 ATOM 2570 C CB . THR A 1 382 ? -11.259 -24.882 27.798 1.00 52.97 ? 355 THR A CB 1 ATOM 2571 O OG1 . THR A 1 382 ? -12.146 -24.055 27.026 1.00 51.73 ? 355 THR A OG1 1 ATOM 2572 C CG2 . THR A 1 382 ? -11.845 -26.281 27.894 1.00 54.26 ? 355 THR A CG2 1 ATOM 2573 N N . PHE A 1 383 ? -8.865 -25.196 29.790 1.00 60.02 ? 356 PHE A N 1 ATOM 2574 C CA . PHE A 1 383 ? -7.945 -26.167 30.387 1.00 58.97 ? 356 PHE A CA 1 ATOM 2575 C C . PHE A 1 383 ? -7.130 -25.613 31.552 1.00 63.93 ? 356 PHE A C 1 ATOM 2576 O O . PHE A 1 383 ? -6.292 -26.321 32.099 1.00 64.70 ? 356 PHE A O 1 ATOM 2577 C CB . PHE A 1 383 ? -7.044 -26.725 29.286 1.00 55.21 ? 356 PHE A CB 1 ATOM 2578 C CG . PHE A 1 383 ? -7.807 -27.411 28.205 1.00 53.84 ? 356 PHE A CG 1 ATOM 2579 C CD1 . PHE A 1 383 ? -8.537 -28.547 28.495 1.00 54.78 ? 356 PHE A CD1 1 ATOM 2580 C CD2 . PHE A 1 383 ? -7.833 -26.915 26.909 1.00 54.71 ? 356 PHE A CD2 1 ATOM 2581 C CE1 . PHE A 1 383 ? -9.256 -29.197 27.514 1.00 54.14 ? 356 PHE A CE1 1 ATOM 2582 C CE2 . PHE A 1 383 ? -8.556 -27.565 25.921 1.00 53.03 ? 356 PHE A CE2 1 ATOM 2583 C CZ . PHE A 1 383 ? -9.261 -28.707 26.223 1.00 52.90 ? 356 PHE A CZ 1 ATOM 2584 N N . ASN A 1 384 ? -7.386 -24.356 31.926 1.00 66.19 ? 357 ASN A N 1 ATOM 2585 C CA . ASN A 1 384 ? -6.730 -23.713 33.072 1.00 65.95 ? 357 ASN A CA 1 ATOM 2586 C C . ASN A 1 384 ? -5.210 -23.743 32.922 1.00 70.11 ? 357 ASN A C 1 ATOM 2587 O O . ASN A 1 384 ? -4.492 -24.161 33.827 1.00 72.71 ? 357 ASN A O 1 ATOM 2588 C CB . ASN A 1 384 ? -7.173 -24.359 34.389 1.00 66.06 ? 357 ASN A CB 1 ATOM 2589 N N . CYS A 1 385 ? -4.728 -23.293 31.766 1.00 69.28 ? 358 CYS A N 1 ATOM 2590 C CA . CYS A 1 385 ? -3.311 -23.385 31.430 1.00 74.11 ? 358 CYS A CA 1 ATOM 2591 C C . CYS A 1 385 ? -2.850 -22.159 30.639 1.00 73.01 ? 358 CYS A C 1 ATOM 2592 O O . CYS A 1 385 ? -3.667 -21.326 30.257 1.00 75.71 ? 358 CYS A O 1 ATOM 2593 C CB . CYS A 1 385 ? -3.039 -24.683 30.650 1.00 78.03 ? 358 CYS A CB 1 ATOM 2594 S SG . CYS A 1 385 ? -3.953 -24.897 29.094 1.00 85.41 ? 358 CYS A SG 1 ATOM 2595 N N . HIS A 1 386 ? -1.543 -22.056 30.402 1.00 73.08 ? 359 HIS A N 1 ATOM 2596 C CA . HIS A 1 386 ? -0.954 -20.930 29.667 1.00 70.73 ? 359 HIS A CA 1 ATOM 2597 C C . HIS A 1 386 ? -0.323 -21.421 28.373 1.00 73.38 ? 359 HIS A C 1 ATOM 2598 O O . HIS A 1 386 ? 0.147 -22.548 28.300 1.00 73.75 ? 359 HIS A O 1 ATOM 2599 C CB . HIS A 1 386 ? 0.112 -20.241 30.519 1.00 65.93 ? 359 HIS A CB 1 ATOM 2600 N N . LEU A 1 387 ? -0.330 -20.578 27.350 1.00 74.84 ? 360 LEU A N 1 ATOM 2601 C CA . LEU A 1 387 ? 0.381 -20.857 26.114 1.00 76.74 ? 360 LEU A CA 1 ATOM 2602 C C . LEU A 1 387 ? 1.558 -19.898 26.026 1.00 74.75 ? 360 LEU A C 1 ATOM 2603 O O . LEU A 1 387 ? 2.375 -19.994 25.117 1.00 82.02 ? 360 LEU A O 1 ATOM 2604 C CB . LEU A 1 387 ? -0.545 -20.665 24.914 1.00 79.81 ? 360 LEU A CB 1 ATOM 2605 C CG . LEU A 1 387 ? -1.750 -21.633 24.776 1.00 83.93 ? 360 LEU A CG 1 ATOM 2606 C CD1 . LEU A 1 387 ? -3.006 -21.002 24.168 1.00 86.11 ? 360 LEU A CD1 1 ATOM 2607 C CD2 . LEU A 1 387 ? -1.347 -22.862 23.972 1.00 85.06 ? 360 LEU A CD2 1 ATOM 2608 N N . ARG A 1 419 ? -0.734 -21.582 37.168 1.00 77.22 ? 392 ARG A N 1 ATOM 2609 C CA . ARG A 1 419 ? -1.250 -22.157 35.922 1.00 80.39 ? 392 ARG A CA 1 ATOM 2610 C C . ARG A 1 419 ? -0.152 -22.761 35.012 1.00 82.03 ? 392 ARG A C 1 ATOM 2611 O O . ARG A 1 419 ? 0.646 -22.024 34.424 1.00 81.07 ? 392 ARG A O 1 ATOM 2612 C CB . ARG A 1 419 ? -2.041 -21.095 35.143 1.00 77.25 ? 392 ARG A CB 1 ATOM 2613 N N . PRO A 1 420 ? -0.132 -24.105 34.862 1.00 81.88 ? 393 PRO A N 1 ATOM 2614 C CA . PRO A 1 420 ? 0.870 -24.761 33.998 1.00 83.09 ? 393 PRO A CA 1 ATOM 2615 C C . PRO A 1 420 ? 0.736 -24.432 32.518 1.00 85.01 ? 393 PRO A C 1 ATOM 2616 O O . PRO A 1 420 ? -0.277 -23.881 32.100 1.00 89.33 ? 393 PRO A O 1 ATOM 2617 C CB . PRO A 1 420 ? 0.579 -26.251 34.173 1.00 82.09 ? 393 PRO A CB 1 ATOM 2618 C CG . PRO A 1 420 ? -0.820 -26.331 34.662 1.00 81.30 ? 393 PRO A CG 1 ATOM 2619 C CD . PRO A 1 420 ? -1.096 -25.070 35.420 1.00 81.72 ? 393 PRO A CD 1 ATOM 2620 N N . LEU A 1 421 ? 1.745 -24.810 31.736 1.00 85.39 ? 394 LEU A N 1 ATOM 2621 C CA . LEU A 1 421 ? 1.706 -24.650 30.274 1.00 82.31 ? 394 LEU A CA 1 ATOM 2622 C C . LEU A 1 421 ? 0.743 -25.645 29.612 1.00 83.33 ? 394 LEU A C 1 ATOM 2623 O O . LEU A 1 421 ? 0.601 -26.770 30.083 1.00 81.73 ? 394 LEU A O 1 ATOM 2624 C CB . LEU A 1 421 ? 3.105 -24.790 29.649 1.00 79.57 ? 394 LEU A CB 1 ATOM 2625 C CG . LEU A 1 421 ? 4.046 -23.581 29.698 1.00 79.83 ? 394 LEU A CG 1 ATOM 2626 C CD1 . LEU A 1 421 ? 5.256 -23.842 28.812 1.00 76.25 ? 394 LEU A CD1 1 ATOM 2627 C CD2 . LEU A 1 421 ? 3.359 -22.286 29.275 1.00 82.70 ? 394 LEU A CD2 1 ATOM 2628 N N . CYS A 1 422 ? 0.086 -25.221 28.526 1.00 87.51 ? 395 CYS A N 1 ATOM 2629 C CA . CYS A 1 422 ? -0.814 -26.096 27.757 1.00 90.95 ? 395 CYS A CA 1 ATOM 2630 C C . CYS A 1 422 ? 0.013 -26.964 26.820 1.00 92.05 ? 395 CYS A C 1 ATOM 2631 O O . CYS A 1 422 ? 0.950 -26.480 26.186 1.00 90.99 ? 395 CYS A O 1 ATOM 2632 C CB . CYS A 1 422 ? -1.827 -25.302 26.904 1.00 92.11 ? 395 CYS A CB 1 ATOM 2633 S SG . CYS A 1 422 ? -2.767 -23.982 27.714 1.00 93.38 ? 395 CYS A SG 1 ATOM 2634 N N . THR A 1 423 ? -0.356 -28.236 26.708 1.00 94.05 ? 396 THR A N 1 ATOM 2635 C CA . THR A 1 423 ? 0.334 -29.157 25.802 1.00 91.06 ? 396 THR A CA 1 ATOM 2636 C C . THR A 1 423 ? 0.022 -28.810 24.338 1.00 95.66 ? 396 THR A C 1 ATOM 2637 O O . THR A 1 423 ? 0.888 -28.924 23.471 1.00 98.05 ? 396 THR A O 1 ATOM 2638 C CB . THR A 1 423 ? -0.021 -30.641 26.089 1.00 85.37 ? 396 THR A CB 1 ATOM 2639 O OG1 . THR A 1 423 ? -1.402 -30.891 25.801 1.00 80.49 ? 396 THR A OG1 1 ATOM 2640 C CG2 . THR A 1 423 ? 0.269 -31.010 27.547 1.00 84.02 ? 396 THR A CG2 1 ATOM 2641 N N . GLY A 1 424 ? -1.203 -28.350 24.078 1.00 96.29 ? 397 GLY A N 1 ATOM 2642 C CA . GLY A 1 424 ? -1.707 -28.172 22.715 1.00 91.46 ? 397 GLY A CA 1 ATOM 2643 C C . GLY A 1 424 ? -2.365 -29.435 22.185 1.00 87.75 ? 397 GLY A C 1 ATOM 2644 O O . GLY A 1 424 ? -2.798 -29.476 21.044 1.00 84.62 ? 397 GLY A O 1 ATOM 2645 N N . ASP A 1 425 ? -2.440 -30.471 23.015 1.00 87.09 ? 398 ASP A N 1 ATOM 2646 C CA . ASP A 1 425 ? -2.980 -31.759 22.597 1.00 89.82 ? 398 ASP A CA 1 ATOM 2647 C C . ASP A 1 425 ? -4.176 -32.158 23.443 1.00 84.62 ? 398 ASP A C 1 ATOM 2648 O O . ASP A 1 425 ? -4.685 -33.265 23.299 1.00 84.13 ? 398 ASP A O 1 ATOM 2649 C CB . ASP A 1 425 ? -1.912 -32.858 22.728 1.00 92.86 ? 398 ASP A CB 1 ATOM 2650 C CG . ASP A 1 425 ? -0.648 -32.560 21.931 1.00 96.07 ? 398 ASP A CG 1 ATOM 2651 O OD1 . ASP A 1 425 ? -0.748 -32.164 20.748 1.00 97.74 ? 398 ASP A OD1 1 ATOM 2652 O OD2 . ASP A 1 425 ? 0.455 -32.734 22.492 1.00 101.02 ? 398 ASP A OD2 1 ATOM 2653 N N . GLU A 1 426 ? -4.627 -31.277 24.332 1.00 77.31 ? 399 GLU A N 1 ATOM 2654 C CA . GLU A 1 426 ? -5.666 -31.669 25.294 1.00 70.01 ? 399 GLU A CA 1 ATOM 2655 C C . GLU A 1 426 ? -7.025 -31.789 24.595 1.00 61.30 ? 399 GLU A C 1 ATOM 2656 O O . GLU A 1 426 ? -7.167 -31.434 23.420 1.00 58.36 ? 399 GLU A O 1 ATOM 2657 C CB . GLU A 1 426 ? -5.692 -30.772 26.556 1.00 69.33 ? 399 GLU A CB 1 ATOM 2658 C CG . GLU A 1 426 ? -5.354 -29.300 26.362 1.00 70.79 ? 399 GLU A CG 1 ATOM 2659 C CD . GLU A 1 426 ? -3.874 -28.985 26.487 1.00 70.13 ? 399 GLU A CD 1 ATOM 2660 O OE1 . GLU A 1 426 ? -3.324 -29.167 27.594 1.00 76.48 ? 399 GLU A OE1 1 ATOM 2661 O OE2 . GLU A 1 426 ? -3.268 -28.524 25.493 1.00 63.76 ? 399 GLU A OE2 1 ATOM 2662 N N . ASN A 1 427 ? -8.009 -32.321 25.307 1.00 58.97 ? 400 ASN A N 1 ATOM 2663 C CA . ASN A 1 427 ? -9.252 -32.746 24.677 1.00 62.91 ? 400 ASN A CA 1 ATOM 2664 C C . ASN A 1 427 ? -10.474 -31.947 25.132 1.00 62.33 ? 400 ASN A C 1 ATOM 2665 O O . ASN A 1 427 ? -10.873 -32.009 26.305 1.00 58.46 ? 400 ASN A O 1 ATOM 2666 C CB . ASN A 1 427 ? -9.480 -34.232 24.955 1.00 63.86 ? 400 ASN A CB 1 ATOM 2667 C CG . ASN A 1 427 ? -10.531 -34.845 24.042 1.00 68.98 ? 400 ASN A CG 1 ATOM 2668 O OD1 . ASN A 1 427 ? -10.794 -34.351 22.942 1.00 70.21 ? 400 ASN A OD1 1 ATOM 2669 N ND2 . ASN A 1 427 ? -11.149 -35.929 24.504 1.00 74.09 ? 400 ASN A ND2 1 ATOM 2670 N N . ILE A 1 428 ? -11.074 -31.220 24.188 1.00 65.39 ? 401 ILE A N 1 ATOM 2671 C CA . ILE A 1 428 ? -12.265 -30.397 24.458 1.00 69.20 ? 401 ILE A CA 1 ATOM 2672 C C . ILE A 1 428 ? -13.355 -31.181 25.206 1.00 66.89 ? 401 ILE A C 1 ATOM 2673 O O . ILE A 1 428 ? -14.052 -30.617 26.045 1.00 61.25 ? 401 ILE A O 1 ATOM 2674 C CB . ILE A 1 428 ? -12.832 -29.786 23.150 1.00 71.40 ? 401 ILE A CB 1 ATOM 2675 C CG1 . ILE A 1 428 ? -11.939 -28.645 22.670 1.00 73.45 ? 401 ILE A CG1 1 ATOM 2676 C CG2 . ILE A 1 428 ? -14.245 -29.239 23.335 1.00 73.39 ? 401 ILE A CG2 1 ATOM 2677 C CD1 . ILE A 1 428 ? -12.052 -28.386 21.183 1.00 75.86 ? 401 ILE A CD1 1 ATOM 2678 N N . SER A 1 429 ? -13.478 -32.482 24.929 1.00 68.54 ? 402 SER A N 1 ATOM 2679 C CA . SER A 1 429 ? -14.528 -33.290 25.560 1.00 66.33 ? 402 SER A CA 1 ATOM 2680 C C . SER A 1 429 ? -14.272 -33.686 27.024 1.00 66.54 ? 402 SER A C 1 ATOM 2681 O O . SER A 1 429 ? -15.168 -34.217 27.674 1.00 73.59 ? 402 SER A O 1 ATOM 2682 C CB . SER A 1 429 ? -14.852 -34.517 24.710 1.00 64.77 ? 402 SER A CB 1 ATOM 2683 O OG . SER A 1 429 ? -15.432 -34.106 23.480 1.00 63.19 ? 402 SER A OG 1 ATOM 2684 N N . SER A 1 430 ? -13.088 -33.408 27.562 1.00 66.42 ? 403 SER A N 1 ATOM 2685 C CA . SER A 1 430 ? -12.778 -33.787 28.946 1.00 71.06 ? 403 SER A CA 1 ATOM 2686 C C . SER A 1 430 ? -13.258 -32.783 30.004 1.00 74.75 ? 403 SER A C 1 ATOM 2687 O O . SER A 1 430 ? -13.338 -33.123 31.191 1.00 71.55 ? 403 SER A O 1 ATOM 2688 C CB . SER A 1 430 ? -11.273 -33.999 29.107 1.00 73.13 ? 403 SER A CB 1 ATOM 2689 O OG . SER A 1 430 ? -10.578 -32.788 28.906 1.00 77.17 ? 403 SER A OG 1 ATOM 2690 N N . VAL A 1 431 ? -13.560 -31.551 29.582 1.00 78.63 ? 404 VAL A N 1 ATOM 2691 C CA . VAL A 1 431 ? -13.943 -30.472 30.509 1.00 76.04 ? 404 VAL A CA 1 ATOM 2692 C C . VAL A 1 431 ? -15.344 -29.970 30.185 1.00 72.36 ? 404 VAL A C 1 ATOM 2693 O O . VAL A 1 431 ? -15.603 -29.563 29.053 1.00 76.63 ? 404 VAL A O 1 ATOM 2694 C CB . VAL A 1 431 ? -12.967 -29.277 30.429 1.00 73.97 ? 404 VAL A CB 1 ATOM 2695 C CG1 . VAL A 1 431 ? -13.218 -28.304 31.575 1.00 71.57 ? 404 VAL A CG1 1 ATOM 2696 C CG2 . VAL A 1 431 ? -11.518 -29.755 30.445 1.00 72.20 ? 404 VAL A CG2 1 ATOM 2697 N N . GLU A 1 432 ? -16.234 -29.987 31.178 1.00 69.43 ? 405 GLU A N 1 ATOM 2698 C CA . GLU A 1 432 ? -17.594 -29.467 31.003 1.00 72.87 ? 405 GLU A CA 1 ATOM 2699 C C . GLU A 1 432 ? -17.655 -27.939 31.171 1.00 66.22 ? 405 GLU A C 1 ATOM 2700 O O . GLU A 1 432 ? -17.376 -27.397 32.244 1.00 65.26 ? 405 GLU A O 1 ATOM 2701 C CB . GLU A 1 432 ? -18.589 -30.170 31.928 1.00 76.18 ? 405 GLU A CB 1 ATOM 2702 C CG . GLU A 1 432 ? -19.163 -31.435 31.301 1.00 84.41 ? 405 GLU A CG 1 ATOM 2703 C CD . GLU A 1 432 ? -19.951 -32.283 32.283 1.00 92.11 ? 405 GLU A CD 1 ATOM 2704 O OE1 . GLU A 1 432 ? -19.777 -33.523 32.271 1.00 96.96 ? 405 GLU A OE1 1 ATOM 2705 O OE2 . GLU A 1 432 ? -20.737 -31.712 33.072 1.00 96.54 ? 405 GLU A OE2 1 ATOM 2706 N N . THR A 1 433 ? -17.971 -27.260 30.070 1.00 59.26 ? 406 THR A N 1 ATOM 2707 C CA . THR A 1 433 ? -18.314 -25.837 30.064 1.00 51.89 ? 406 THR A CA 1 ATOM 2708 C C . THR A 1 433 ? -19.534 -25.703 29.172 1.00 53.61 ? 406 THR A C 1 ATOM 2709 O O . THR A 1 433 ? -19.901 -26.655 28.488 1.00 51.72 ? 406 THR A O 1 ATOM 2710 C CB . THR A 1 433 ? -17.193 -24.970 29.462 1.00 49.92 ? 406 THR A CB 1 ATOM 2711 O OG1 . THR A 1 433 ? -17.040 -25.270 28.068 1.00 45.62 ? 406 THR A OG1 1 ATOM 2712 C CG2 . THR A 1 433 ? -15.847 -25.183 30.203 1.00 50.74 ? 406 THR A CG2 1 ATOM 2713 N N . PRO A 1 434 ? -20.164 -24.515 29.142 1.00 51.10 ? 407 PRO A N 1 ATOM 2714 C CA . PRO A 1 434 ? -21.281 -24.327 28.196 1.00 47.77 ? 407 PRO A CA 1 ATOM 2715 C C . PRO A 1 434 ? -20.899 -24.403 26.715 1.00 47.15 ? 407 PRO A C 1 ATOM 2716 O O . PRO A 1 434 ? -21.774 -24.481 25.859 1.00 49.50 ? 407 PRO A O 1 ATOM 2717 C CB . PRO A 1 434 ? -21.798 -22.931 28.550 1.00 47.95 ? 407 PRO A CB 1 ATOM 2718 C CG . PRO A 1 434 ? -21.470 -22.790 30.001 1.00 48.12 ? 407 PRO A CG 1 ATOM 2719 C CD . PRO A 1 434 ? -20.150 -23.480 30.193 1.00 48.18 ? 407 PRO A CD 1 ATOM 2720 N N . TYR A 1 435 ? -19.610 -24.385 26.405 1.00 44.89 ? 408 TYR A N 1 ATOM 2721 C CA . TYR A 1 435 ? -19.191 -24.430 25.019 1.00 48.29 ? 408 TYR A CA 1 ATOM 2722 C C . TYR A 1 435 ? -19.828 -25.603 24.294 1.00 51.40 ? 408 TYR A C 1 ATOM 2723 O O . TYR A 1 435 ? -20.423 -25.439 23.227 1.00 46.11 ? 408 TYR A O 1 ATOM 2724 C CB . TYR A 1 435 ? -17.676 -24.552 24.916 1.00 48.03 ? 408 TYR A CB 1 ATOM 2725 C CG . TYR A 1 435 ? -17.157 -24.592 23.495 1.00 49.82 ? 408 TYR A CG 1 ATOM 2726 C CD1 . TYR A 1 435 ? -17.415 -23.551 22.629 1.00 48.90 ? 408 TYR A CD1 1 ATOM 2727 C CD2 . TYR A 1 435 ? -16.372 -25.656 23.029 1.00 50.51 ? 408 TYR A CD2 1 ATOM 2728 C CE1 . TYR A 1 435 ? -16.939 -23.558 21.337 1.00 51.94 ? 408 TYR A CE1 1 ATOM 2729 C CE2 . TYR A 1 435 ? -15.883 -25.669 21.725 1.00 50.53 ? 408 TYR A CE2 1 ATOM 2730 C CZ . TYR A 1 435 ? -16.173 -24.611 20.881 1.00 51.86 ? 408 TYR A CZ 1 ATOM 2731 O OH . TYR A 1 435 ? -15.721 -24.547 19.580 1.00 47.30 ? 408 TYR A OH 1 ATOM 2732 N N . ILE A 1 436 ? -19.676 -26.784 24.885 1.00 52.71 ? 409 ILE A N 1 ATOM 2733 C CA . ILE A 1 436 ? -20.179 -28.018 24.299 1.00 57.48 ? 409 ILE A CA 1 ATOM 2734 C C . ILE A 1 436 ? -21.223 -28.725 25.164 1.00 58.35 ? 409 ILE A C 1 ATOM 2735 O O . ILE A 1 436 ? -21.952 -29.562 24.661 1.00 56.94 ? 409 ILE A O 1 ATOM 2736 C CB . ILE A 1 436 ? -18.998 -28.957 23.929 1.00 61.77 ? 409 ILE A CB 1 ATOM 2737 C CG1 . ILE A 1 436 ? -19.171 -29.444 22.512 1.00 65.12 ? 409 ILE A CG1 1 ATOM 2738 C CG2 . ILE A 1 436 ? -18.812 -30.117 24.911 1.00 64.61 ? 409 ILE A CG2 1 ATOM 2739 C CD1 . ILE A 1 436 ? -18.856 -28.373 21.500 1.00 65.63 ? 409 ILE A CD1 1 ATOM 2740 N N . ASP A 1 437 ? -21.307 -28.394 26.449 1.00 55.77 ? 410 ASP A N 1 ATOM 2741 C CA . ASP A 1 437 ? -22.343 -28.962 27.290 1.00 59.70 ? 410 ASP A CA 1 ATOM 2742 C C . ASP A 1 437 ? -23.653 -28.224 27.064 1.00 58.10 ? 410 ASP A C 1 ATOM 2743 O O . ASP A 1 437 ? -24.024 -27.348 27.839 1.00 60.78 ? 410 ASP A O 1 ATOM 2744 C CB . ASP A 1 437 ? -21.940 -28.907 28.772 1.00 65.27 ? 410 ASP A CB 1 ATOM 2745 C CG . ASP A 1 437 ? -22.986 -29.527 29.700 1.00 70.15 ? 410 ASP A CG 1 ATOM 2746 O OD1 . ASP A 1 437 ? -23.868 -30.270 29.206 1.00 80.02 ? 410 ASP A OD1 1 ATOM 2747 O OD2 . ASP A 1 437 ? -22.920 -29.270 30.928 1.00 71.33 ? 410 ASP A OD2 1 ATOM 2748 N N . TYR A 1 438 ? -24.350 -28.587 25.998 1.00 55.47 ? 411 TYR A N 1 ATOM 2749 C CA . TYR A 1 438 ? -25.698 -28.072 25.754 1.00 55.45 ? 411 TYR A CA 1 ATOM 2750 C C . TYR A 1 438 ? -26.556 -29.164 25.139 1.00 55.06 ? 411 TYR A C 1 ATOM 2751 O O . TYR A 1 438 ? -26.027 -30.053 24.470 1.00 49.63 ? 411 TYR A O 1 ATOM 2752 C CB . TYR A 1 438 ? -25.654 -26.890 24.782 1.00 53.21 ? 411 TYR A CB 1 ATOM 2753 C CG . TYR A 1 438 ? -25.137 -27.281 23.414 1.00 48.48 ? 411 TYR A CG 1 ATOM 2754 C CD1 . TYR A 1 438 ? -25.989 -27.826 22.451 1.00 46.77 ? 411 TYR A CD1 1 ATOM 2755 C CD2 . TYR A 1 438 ? -23.792 -27.117 23.085 1.00 47.91 ? 411 TYR A CD2 1 ATOM 2756 C CE1 . TYR A 1 438 ? -25.521 -28.178 21.196 1.00 42.76 ? 411 TYR A CE1 1 ATOM 2757 C CE2 . TYR A 1 438 ? -23.323 -27.466 21.828 1.00 46.17 ? 411 TYR A CE2 1 ATOM 2758 C CZ . TYR A 1 438 ? -24.192 -28.005 20.894 1.00 44.77 ? 411 TYR A CZ 1 ATOM 2759 O OH . TYR A 1 438 ? -23.716 -28.362 19.643 1.00 48.44 ? 411 TYR A OH 1 ATOM 2760 N N . THR A 1 439 ? -27.869 -29.053 25.357 1.00 59.42 ? 412 THR A N 1 ATOM 2761 C CA . THR A 1 439 ? -28.889 -29.901 24.745 1.00 61.03 ? 412 THR A CA 1 ATOM 2762 C C . THR A 1 439 ? -29.430 -29.251 23.487 1.00 57.53 ? 412 THR A C 1 ATOM 2763 O O . THR A 1 439 ? -29.416 -29.837 22.423 1.00 58.62 ? 412 THR A O 1 ATOM 2764 C CB . THR A 1 439 ? -30.110 -30.066 25.683 1.00 67.11 ? 412 THR A CB 1 ATOM 2765 O OG1 . THR A 1 439 ? -29.685 -30.438 27.001 1.00 69.08 ? 412 THR A OG1 1 ATOM 2766 C CG2 . THR A 1 439 ? -31.067 -31.122 25.139 1.00 72.42 ? 412 THR A CG2 1 ATOM 2767 N N . HIS A 1 440 ? -29.942 -28.035 23.635 1.00 56.40 ? 413 HIS A N 1 ATOM 2768 C CA . HIS A 1 440 ? -30.604 -27.348 22.549 1.00 56.58 ? 413 HIS A CA 1 ATOM 2769 C C . HIS A 1 440 ? -29.842 -26.114 22.100 1.00 52.31 ? 413 HIS A C 1 ATOM 2770 O O . HIS A 1 440 ? -29.294 -25.374 22.912 1.00 54.62 ? 413 HIS A O 1 ATOM 2771 C CB . HIS A 1 440 ? -31.992 -26.892 22.983 1.00 62.04 ? 413 HIS A CB 1 ATOM 2772 C CG . HIS A 1 440 ? -32.806 -27.952 23.641 1.00 67.80 ? 413 HIS A CG 1 ATOM 2773 N ND1 . HIS A 1 440 ? -33.502 -28.901 22.923 1.00 71.67 ? 413 HIS A ND1 1 ATOM 2774 C CD2 . HIS A 1 440 ? -33.057 -28.202 24.948 1.00 68.46 ? 413 HIS A CD2 1 ATOM 2775 C CE1 . HIS A 1 440 ? -34.141 -29.697 23.762 1.00 71.49 ? 413 HIS A CE1 1 ATOM 2776 N NE2 . HIS A 1 440 ? -33.890 -29.292 24.995 1.00 72.88 ? 413 HIS A NE2 1 ATOM 2777 N N . LEU A 1 441 ? -29.854 -25.880 20.797 1.00 48.16 ? 414 LEU A N 1 ATOM 2778 C CA . LEU A 1 441 ? -29.377 -24.635 20.232 1.00 43.29 ? 414 LEU A CA 1 ATOM 2779 C C . LEU A 1 441 ? -30.553 -23.679 20.072 1.00 44.54 ? 414 LEU A C 1 ATOM 2780 O O . LEU A 1 441 ? -31.510 -23.991 19.367 1.00 39.94 ? 414 LEU A O 1 ATOM 2781 C CB . LEU A 1 441 ? -28.762 -24.886 18.868 1.00 38.69 ? 414 LEU A CB 1 ATOM 2782 C CG . LEU A 1 441 ? -27.580 -25.838 18.882 1.00 39.02 ? 414 LEU A CG 1 ATOM 2783 C CD1 . LEU A 1 441 ? -27.261 -26.305 17.469 1.00 39.50 ? 414 LEU A CD1 1 ATOM 2784 C CD2 . LEU A 1 441 ? -26.361 -25.163 19.507 1.00 39.26 ? 414 LEU A CD2 1 ATOM 2785 N N . ARG A 1 442 ? -30.489 -22.528 20.748 1.00 46.59 ? 415 ARG A N 1 ATOM 2786 C CA . ARG A 1 442 ? -31.574 -21.545 20.692 1.00 42.29 ? 415 ARG A CA 1 ATOM 2787 C C . ARG A 1 442 ? -31.036 -20.220 20.204 1.00 37.91 ? 415 ARG A C 1 ATOM 2788 O O . ARG A 1 442 ? -31.221 -19.907 19.033 1.00 34.93 ? 415 ARG A O 1 ATOM 2789 C CB . ARG A 1 442 ? -32.259 -21.428 22.040 1.00 43.52 ? 415 ARG A CB 1 ATOM 2790 C CG . ARG A 1 442 ? -32.738 -22.760 22.546 1.00 47.41 ? 415 ARG A CG 1 ATOM 2791 C CD . ARG A 1 442 ? -33.780 -22.566 23.612 1.00 50.36 ? 415 ARG A CD 1 ATOM 2792 N NE . ARG A 1 442 ? -33.688 -23.597 24.636 1.00 57.25 ? 415 ARG A NE 1 ATOM 2793 C CZ . ARG A 1 442 ? -34.561 -24.585 24.827 1.00 58.86 ? 415 ARG A CZ 1 ATOM 2794 N NH1 . ARG A 1 442 ? -35.645 -24.740 24.066 1.00 54.52 ? 415 ARG A NH1 1 ATOM 2795 N NH2 . ARG A 1 442 ? -34.340 -25.436 25.815 1.00 67.19 ? 415 ARG A NH2 1 ATOM 2796 N N . ILE A 1 443 ? -30.319 -19.477 21.058 1.00 35.57 ? 416 ILE A N 1 ATOM 2797 C CA . ILE A 1 443 ? -29.648 -18.268 20.588 1.00 34.87 ? 416 ILE A CA 1 ATOM 2798 C C . ILE A 1 443 ? -28.659 -18.620 19.469 1.00 33.02 ? 416 ILE A C 1 ATOM 2799 O O . ILE A 1 443 ? -28.529 -17.887 18.508 1.00 34.27 ? 416 ILE A O 1 ATOM 2800 C CB . ILE A 1 443 ? -28.918 -17.494 21.709 1.00 32.83 ? 416 ILE A CB 1 ATOM 2801 C CG1 . ILE A 1 443 ? -29.872 -17.114 22.847 1.00 31.84 ? 416 ILE A CG1 1 ATOM 2802 C CG2 . ILE A 1 443 ? -28.245 -16.250 21.143 1.00 31.18 ? 416 ILE A CG2 1 ATOM 2803 C CD1 . ILE A 1 443 ? -30.991 -16.196 22.451 1.00 31.01 ? 416 ILE A CD1 1 ATOM 2804 N N . SER A 1 444 ? -27.966 -19.743 19.588 1.00 35.41 ? 417 SER A N 1 ATOM 2805 C CA . SER A 1 444 ? -27.033 -20.194 18.526 1.00 35.16 ? 417 SER A CA 1 ATOM 2806 C C . SER A 1 444 ? -27.746 -20.356 17.193 1.00 34.30 ? 417 SER A C 1 ATOM 2807 O O . SER A 1 444 ? -27.217 -20.014 16.132 1.00 33.45 ? 417 SER A O 1 ATOM 2808 C CB . SER A 1 444 ? -26.386 -21.534 18.898 1.00 36.16 ? 417 SER A CB 1 ATOM 2809 O OG . SER A 1 444 ? -25.819 -21.510 20.193 1.00 36.25 ? 417 SER A OG 1 ATOM 2810 N N . TYR A 1 445 ? -28.972 -20.851 17.243 1.00 34.54 ? 418 TYR A N 1 ATOM 2811 C CA . TYR A 1 445 ? -29.750 -20.971 16.035 1.00 36.69 ? 418 TYR A CA 1 ATOM 2812 C C . TYR A 1 445 ? -30.102 -19.600 15.475 1.00 36.65 ? 418 TYR A C 1 ATOM 2813 O O . TYR A 1 445 ? -30.032 -19.399 14.265 1.00 42.13 ? 418 TYR A O 1 ATOM 2814 C CB . TYR A 1 445 ? -31.004 -21.802 16.268 1.00 37.11 ? 418 TYR A CB 1 ATOM 2815 C CG . TYR A 1 445 ? -31.691 -22.154 14.985 1.00 41.26 ? 418 TYR A CG 1 ATOM 2816 C CD1 . TYR A 1 445 ? -31.067 -22.967 14.051 1.00 43.31 ? 418 TYR A CD1 1 ATOM 2817 C CD2 . TYR A 1 445 ? -32.966 -21.682 14.695 1.00 46.80 ? 418 TYR A CD2 1 ATOM 2818 C CE1 . TYR A 1 445 ? -31.673 -23.289 12.855 1.00 44.90 ? 418 TYR A CE1 1 ATOM 2819 C CE2 . TYR A 1 445 ? -33.598 -22.021 13.505 1.00 47.87 ? 418 TYR A CE2 1 ATOM 2820 C CZ . TYR A 1 445 ? -32.937 -22.825 12.585 1.00 46.90 ? 418 TYR A CZ 1 ATOM 2821 O OH . TYR A 1 445 ? -33.534 -23.167 11.391 1.00 51.02 ? 418 TYR A OH 1 ATOM 2822 N N . ASN A 1 446 ? -30.468 -18.650 16.343 1.00 35.97 ? 419 ASN A N 1 ATOM 2823 C CA . ASN A 1 446 ? -30.718 -17.261 15.907 1.00 33.65 ? 419 ASN A CA 1 ATOM 2824 C C . ASN A 1 446 ? -29.517 -16.646 15.186 1.00 32.02 ? 419 ASN A C 1 ATOM 2825 O O . ASN A 1 446 ? -29.659 -15.873 14.235 1.00 33.52 ? 419 ASN A O 1 ATOM 2826 C CB . ASN A 1 446 ? -31.090 -16.374 17.103 1.00 32.91 ? 419 ASN A CB 1 ATOM 2827 C CG . ASN A 1 446 ? -32.401 -16.776 17.752 1.00 33.57 ? 419 ASN A CG 1 ATOM 2828 O OD1 . ASN A 1 446 ? -33.115 -17.651 17.260 1.00 34.13 ? 419 ASN A OD1 1 ATOM 2829 N ND2 . ASN A 1 446 ? -32.727 -16.136 18.864 1.00 33.53 ? 419 ASN A ND2 1 ATOM 2830 N N . VAL A 1 447 ? -28.332 -16.960 15.670 1.00 32.66 ? 420 VAL A N 1 ATOM 2831 C CA . VAL A 1 447 ? -27.127 -16.438 15.037 1.00 34.85 ? 420 VAL A CA 1 ATOM 2832 C C . VAL A 1 447 ? -27.001 -16.978 13.621 1.00 37.38 ? 420 VAL A C 1 ATOM 2833 O O . VAL A 1 447 ? -26.754 -16.227 12.671 1.00 37.17 ? 420 VAL A O 1 ATOM 2834 C CB . VAL A 1 447 ? -25.868 -16.829 15.812 1.00 34.39 ? 420 VAL A CB 1 ATOM 2835 C CG1 . VAL A 1 447 ? -24.627 -16.324 15.077 1.00 35.62 ? 420 VAL A CG1 1 ATOM 2836 C CG2 . VAL A 1 447 ? -25.919 -16.276 17.221 1.00 34.42 ? 420 VAL A CG2 1 ATOM 2837 N N . TYR A 1 448 ? -27.183 -18.297 13.514 1.00 39.07 ? 421 TYR A N 1 ATOM 2838 C CA . TYR A 1 448 ? -27.194 -19.038 12.249 1.00 39.26 ? 421 TYR A CA 1 ATOM 2839 C C . TYR A 1 448 ? -28.191 -18.451 11.273 1.00 35.59 ? 421 TYR A C 1 ATOM 2840 O O . TYR A 1 448 ? -27.859 -18.163 10.123 1.00 39.17 ? 421 TYR A O 1 ATOM 2841 C CB . TYR A 1 448 ? -27.529 -20.502 12.571 1.00 44.71 ? 421 TYR A CB 1 ATOM 2842 C CG . TYR A 1 448 ? -27.507 -21.488 11.434 1.00 47.99 ? 421 TYR A CG 1 ATOM 2843 C CD1 . TYR A 1 448 ? -26.301 -21.923 10.890 1.00 52.33 ? 421 TYR A CD1 1 ATOM 2844 C CD2 . TYR A 1 448 ? -28.692 -22.042 10.943 1.00 51.41 ? 421 TYR A CD2 1 ATOM 2845 C CE1 . TYR A 1 448 ? -26.275 -22.853 9.858 1.00 54.20 ? 421 TYR A CE1 1 ATOM 2846 C CE2 . TYR A 1 448 ? -28.677 -22.973 9.915 1.00 54.56 ? 421 TYR A CE2 1 ATOM 2847 C CZ . TYR A 1 448 ? -27.465 -23.379 9.377 1.00 55.87 ? 421 TYR A CZ 1 ATOM 2848 O OH . TYR A 1 448 ? -27.437 -24.309 8.364 1.00 58.26 ? 421 TYR A OH 1 ATOM 2849 N N . LEU A 1 449 ? -29.414 -18.246 11.733 1.00 37.40 ? 422 LEU A N 1 ATOM 2850 C CA . LEU A 1 449 ? -30.449 -17.609 10.899 1.00 36.97 ? 422 LEU A CA 1 ATOM 2851 C C . LEU A 1 449 ? -30.149 -16.180 10.535 1.00 36.26 ? 422 LEU A C 1 ATOM 2852 O O . LEU A 1 449 ? -30.563 -15.721 9.480 1.00 37.21 ? 422 LEU A O 1 ATOM 2853 C CB . LEU A 1 449 ? -31.808 -17.646 11.578 1.00 40.15 ? 422 LEU A CB 1 ATOM 2854 C CG . LEU A 1 449 ? -32.563 -18.968 11.637 1.00 47.67 ? 422 LEU A CG 1 ATOM 2855 C CD1 . LEU A 1 449 ? -33.902 -18.727 12.324 1.00 47.11 ? 422 LEU A CD1 1 ATOM 2856 C CD2 . LEU A 1 449 ? -32.773 -19.541 10.235 1.00 47.58 ? 422 LEU A CD2 1 ATOM 2857 N N . ALA A 1 450 ? -29.477 -15.444 11.417 1.00 35.97 ? 423 ALA A N 1 ATOM 2858 C CA . ALA A 1 450 ? -29.125 -14.057 11.095 1.00 35.95 ? 423 ALA A CA 1 ATOM 2859 C C . ALA A 1 450 ? -28.165 -14.017 9.908 1.00 35.65 ? 423 ALA A C 1 ATOM 2860 O O . ALA A 1 450 ? -28.304 -13.200 8.999 1.00 35.52 ? 423 ALA A O 1 ATOM 2861 C CB . ALA A 1 450 ? -28.493 -13.356 12.298 1.00 36.70 ? 423 ALA A CB 1 ATOM 2862 N N . VAL A 1 451 ? -27.182 -14.902 9.922 1.00 39.19 ? 424 VAL A N 1 ATOM 2863 C CA . VAL A 1 451 ? -26.212 -14.949 8.835 1.00 39.34 ? 424 VAL A CA 1 ATOM 2864 C C . VAL A 1 451 ? -26.903 -15.376 7.526 1.00 40.42 ? 424 VAL A C 1 ATOM 2865 O O . VAL A 1 451 ? -26.702 -14.773 6.469 1.00 40.46 ? 424 VAL A O 1 ATOM 2866 C CB . VAL A 1 451 ? -25.070 -15.919 9.173 1.00 41.03 ? 424 VAL A CB 1 ATOM 2867 C CG1 . VAL A 1 451 ? -24.164 -16.124 7.965 1.00 44.51 ? 424 VAL A CG1 1 ATOM 2868 C CG2 . VAL A 1 451 ? -24.268 -15.401 10.361 1.00 41.79 ? 424 VAL A CG2 1 ATOM 2869 N N . TYR A 1 452 ? -27.749 -16.396 7.616 1.00 39.84 ? 425 TYR A N 1 ATOM 2870 C CA . TYR A 1 452 ? -28.488 -16.880 6.449 1.00 41.78 ? 425 TYR A CA 1 ATOM 2871 C C . TYR A 1 452 ? -29.494 -15.848 5.913 1.00 41.84 ? 425 TYR A C 1 ATOM 2872 O O . TYR A 1 452 ? -29.728 -15.776 4.704 1.00 40.99 ? 425 TYR A O 1 ATOM 2873 C CB . TYR A 1 452 ? -29.152 -18.241 6.758 1.00 42.45 ? 425 TYR A CB 1 ATOM 2874 C CG . TYR A 1 452 ? -28.290 -19.425 6.331 1.00 45.55 ? 425 TYR A CG 1 ATOM 2875 C CD1 . TYR A 1 452 ? -28.357 -19.928 5.028 1.00 48.02 ? 425 TYR A CD1 1 ATOM 2876 C CD2 . TYR A 1 452 ? -27.402 -20.023 7.212 1.00 45.72 ? 425 TYR A CD2 1 ATOM 2877 C CE1 . TYR A 1 452 ? -27.566 -21.000 4.621 1.00 48.36 ? 425 TYR A CE1 1 ATOM 2878 C CE2 . TYR A 1 452 ? -26.601 -21.088 6.816 1.00 50.20 ? 425 TYR A CE2 1 ATOM 2879 C CZ . TYR A 1 452 ? -26.688 -21.575 5.517 1.00 51.56 ? 425 TYR A CZ 1 ATOM 2880 O OH . TYR A 1 452 ? -25.881 -22.627 5.139 1.00 51.26 ? 425 TYR A OH 1 ATOM 2881 N N . SER A 1 453 ? -30.084 -15.042 6.803 1.00 38.90 ? 426 SER A N 1 ATOM 2882 C CA . SER A 1 453 ? -30.945 -13.947 6.370 1.00 36.59 ? 426 SER A CA 1 ATOM 2883 C C . SER A 1 453 ? -30.158 -12.983 5.497 1.00 35.84 ? 426 SER A C 1 ATOM 2884 O O . SER A 1 453 ? -30.602 -12.574 4.424 1.00 37.19 ? 426 SER A O 1 ATOM 2885 C CB . SER A 1 453 ? -31.562 -13.215 7.574 1.00 36.83 ? 426 SER A CB 1 ATOM 2886 O OG . SER A 1 453 ? -32.462 -14.052 8.291 1.00 38.46 ? 426 SER A OG 1 ATOM 2887 N N . ILE A 1 454 ? -28.957 -12.643 5.929 1.00 36.50 ? 427 ILE A N 1 ATOM 2888 C CA . ILE A 1 454 ? -28.126 -11.746 5.136 1.00 37.49 ? 427 ILE A CA 1 ATOM 2889 C C . ILE A 1 454 ? -27.749 -12.405 3.799 1.00 39.50 ? 427 ILE A C 1 ATOM 2890 O O . ILE A 1 454 ? -27.802 -11.769 2.744 1.00 37.02 ? 427 ILE A O 1 ATOM 2891 C CB . ILE A 1 454 ? -26.865 -11.337 5.921 1.00 37.57 ? 427 ILE A CB 1 ATOM 2892 C CG1 . ILE A 1 454 ? -27.280 -10.476 7.127 1.00 38.74 ? 427 ILE A CG1 1 ATOM 2893 C CG2 . ILE A 1 454 ? -25.896 -10.561 5.035 1.00 38.09 ? 427 ILE A CG2 1 ATOM 2894 C CD1 . ILE A 1 454 ? -26.237 -10.396 8.216 1.00 37.46 ? 427 ILE A CD1 1 ATOM 2895 N N . ALA A 1 455 ? -27.356 -13.671 3.862 1.00 40.22 ? 428 ALA A N 1 ATOM 2896 C CA . ALA A 1 455 ? -26.928 -14.406 2.674 1.00 42.26 ? 428 ALA A CA 1 ATOM 2897 C C . ALA A 1 455 ? -28.063 -14.521 1.643 1.00 43.61 ? 428 ALA A C 1 ATOM 2898 O O . ALA A 1 455 ? -27.852 -14.301 0.448 1.00 42.35 ? 428 ALA A O 1 ATOM 2899 C CB . ALA A 1 455 ? -26.436 -15.788 3.075 1.00 43.55 ? 428 ALA A CB 1 ATOM 2900 N N . HIS A 1 456 ? -29.262 -14.848 2.113 1.00 41.47 ? 429 HIS A N 1 ATOM 2901 C CA . HIS A 1 456 ? -30.418 -14.926 1.241 1.00 43.88 ? 429 HIS A CA 1 ATOM 2902 C C . HIS A 1 456 ? -30.826 -13.595 0.647 1.00 45.40 ? 429 HIS A C 1 ATOM 2903 O O . HIS A 1 456 ? -31.366 -13.564 -0.455 1.00 42.57 ? 429 HIS A O 1 ATOM 2904 C CB . HIS A 1 456 ? -31.609 -15.558 1.950 1.00 45.35 ? 429 HIS A CB 1 ATOM 2905 C CG . HIS A 1 456 ? -31.509 -17.041 2.047 1.00 50.22 ? 429 HIS A CG 1 ATOM 2906 N ND1 . HIS A 1 456 ? -31.504 -17.855 0.937 1.00 54.25 ? 429 HIS A ND1 1 ATOM 2907 C CD2 . HIS A 1 456 ? -31.378 -17.861 3.118 1.00 53.73 ? 429 HIS A CD2 1 ATOM 2908 C CE1 . HIS A 1 456 ? -31.383 -19.114 1.319 1.00 55.48 ? 429 HIS A CE1 1 ATOM 2909 N NE2 . HIS A 1 456 ? -31.303 -19.144 2.638 1.00 54.62 ? 429 HIS A NE2 1 ATOM 2910 N N . ALA A 1 457 ? -30.609 -12.499 1.377 1.00 43.92 ? 430 ALA A N 1 ATOM 2911 C CA . ALA A 1 457 ? -30.930 -11.190 0.840 1.00 42.11 ? 430 ALA A CA 1 ATOM 2912 C C . ALA A 1 457 ? -29.962 -10.885 -0.299 1.00 43.64 ? 430 ALA A C 1 ATOM 2913 O O . ALA A 1 457 ? -30.364 -10.309 -1.319 1.00 42.12 ? 430 ALA A O 1 ATOM 2914 C CB . ALA A 1 457 ? -30.840 -10.118 1.916 1.00 41.00 ? 430 ALA A CB 1 ATOM 2915 N N . LEU A 1 458 ? -28.693 -11.239 -0.090 1.00 40.40 ? 431 LEU A N 1 ATOM 2916 C CA . LEU A 1 458 ? -27.681 -11.139 -1.120 1.00 43.00 ? 431 LEU A CA 1 ATOM 2917 C C . LEU A 1 458 ? -28.009 -12.056 -2.315 1.00 48.11 ? 431 LEU A C 1 ATOM 2918 O O . LEU A 1 458 ? -27.799 -11.682 -3.453 1.00 44.60 ? 431 LEU A O 1 ATOM 2919 C CB . LEU A 1 458 ? -26.307 -11.513 -0.566 1.00 42.04 ? 431 LEU A CB 1 ATOM 2920 C CG . LEU A 1 458 ? -25.686 -10.545 0.442 1.00 42.83 ? 431 LEU A CG 1 ATOM 2921 C CD1 . LEU A 1 458 ? -24.504 -11.184 1.153 1.00 40.94 ? 431 LEU A CD1 1 ATOM 2922 C CD2 . LEU A 1 458 ? -25.262 -9.248 -0.245 1.00 44.67 ? 431 LEU A CD2 1 ATOM 2923 N N . GLN A 1 459 ? -28.527 -13.248 -2.049 1.00 50.55 ? 432 GLN A N 1 ATOM 2924 C CA . GLN A 1 459 ? -28.892 -14.163 -3.125 1.00 55.02 ? 432 GLN A CA 1 ATOM 2925 C C . GLN A 1 459 ? -30.031 -13.568 -3.953 1.00 53.96 ? 432 GLN A C 1 ATOM 2926 O O . GLN A 1 459 ? -30.030 -13.707 -5.174 1.00 48.24 ? 432 GLN A O 1 ATOM 2927 C CB . GLN A 1 459 ? -29.272 -15.541 -2.566 1.00 57.01 ? 432 GLN A CB 1 ATOM 2928 C CG . GLN A 1 459 ? -29.655 -16.603 -3.597 1.00 60.07 ? 432 GLN A CG 1 ATOM 2929 C CD . GLN A 1 459 ? -28.487 -17.092 -4.463 1.00 65.69 ? 432 GLN A CD 1 ATOM 2930 O OE1 . GLN A 1 459 ? -27.315 -16.759 -4.228 1.00 65.57 ? 432 GLN A OE1 1 ATOM 2931 N NE2 . GLN A 1 459 ? -28.807 -17.909 -5.464 1.00 63.80 ? 432 GLN A NE2 1 ATOM 2932 N N . ASP A 1 460 ? -30.992 -12.910 -3.295 1.00 52.77 ? 433 ASP A N 1 ATOM 2933 C CA . ASP A 1 460 ? -32.100 -12.244 -3.987 1.00 49.28 ? 433 ASP A CA 1 ATOM 2934 C C . ASP A 1 460 ? -31.579 -11.151 -4.897 1.00 51.26 ? 433 ASP A C 1 ATOM 2935 O O . ASP A 1 460 ? -32.199 -10.838 -5.920 1.00 52.59 ? 433 ASP A O 1 ATOM 2936 C CB . ASP A 1 460 ? -33.120 -11.649 -3.009 1.00 52.66 ? 433 ASP A CB 1 ATOM 2937 C CG . ASP A 1 460 ? -33.990 -12.711 -2.331 1.00 54.90 ? 433 ASP A CG 1 ATOM 2938 O OD1 . ASP A 1 460 ? -33.960 -13.891 -2.724 1.00 57.15 ? 433 ASP A OD1 1 ATOM 2939 O OD2 . ASP A 1 460 ? -34.728 -12.359 -1.390 1.00 56.00 ? 433 ASP A OD2 1 ATOM 2940 N N . ILE A 1 461 ? -30.464 -10.533 -4.521 1.00 50.66 ? 434 ILE A N 1 ATOM 2941 C CA . ILE A 1 461 ? -29.844 -9.543 -5.394 1.00 55.53 ? 434 ILE A CA 1 ATOM 2942 C C . ILE A 1 461 ? -29.217 -10.261 -6.590 1.00 58.42 ? 434 ILE A C 1 ATOM 2943 O O . ILE A 1 461 ? -29.376 -9.814 -7.719 1.00 56.29 ? 434 ILE A O 1 ATOM 2944 C CB . ILE A 1 461 ? -28.790 -8.677 -4.671 1.00 53.81 ? 434 ILE A CB 1 ATOM 2945 C CG1 . ILE A 1 461 ? -29.482 -7.713 -3.702 1.00 54.82 ? 434 ILE A CG1 1 ATOM 2946 C CG2 . ILE A 1 461 ? -27.969 -7.866 -5.675 1.00 54.00 ? 434 ILE A CG2 1 ATOM 2947 C CD1 . ILE A 1 461 ? -28.527 -7.007 -2.753 1.00 54.15 ? 434 ILE A CD1 1 ATOM 2948 N N . TYR A 1 462 ? -28.499 -11.354 -6.321 1.00 64.72 ? 435 TYR A N 1 ATOM 2949 C CA . TYR A 1 462 ? -27.840 -12.139 -7.364 1.00 69.04 ? 435 TYR A CA 1 ATOM 2950 C C . TYR A 1 462 ? -28.836 -12.560 -8.451 1.00 66.40 ? 435 TYR A C 1 ATOM 2951 O O . TYR A 1 462 ? -28.544 -12.456 -9.626 1.00 69.13 ? 435 TYR A O 1 ATOM 2952 C CB . TYR A 1 462 ? -27.150 -13.381 -6.770 1.00 75.57 ? 435 TYR A CB 1 ATOM 2953 C CG . TYR A 1 462 ? -26.286 -14.148 -7.764 1.00 82.90 ? 435 TYR A CG 1 ATOM 2954 C CD1 . TYR A 1 462 ? -26.866 -14.947 -8.752 1.00 89.11 ? 435 TYR A CD1 1 ATOM 2955 C CD2 . TYR A 1 462 ? -24.889 -14.079 -7.711 1.00 86.72 ? 435 TYR A CD2 1 ATOM 2956 C CE1 . TYR A 1 462 ? -26.089 -15.646 -9.661 1.00 94.30 ? 435 TYR A CE1 1 ATOM 2957 C CE2 . TYR A 1 462 ? -24.101 -14.778 -8.616 1.00 91.99 ? 435 TYR A CE2 1 ATOM 2958 C CZ . TYR A 1 462 ? -24.708 -15.559 -9.591 1.00 96.22 ? 435 TYR A CZ 1 ATOM 2959 O OH . TYR A 1 462 ? -23.950 -16.256 -10.506 1.00 100.60 ? 435 TYR A OH 1 ATOM 2960 N N . THR A 1 463 ? -30.007 -13.026 -8.035 1.00 64.20 ? 436 THR A N 1 ATOM 2961 C CA . THR A 1 463 ? -31.022 -13.574 -8.926 1.00 59.86 ? 436 THR A CA 1 ATOM 2962 C C . THR A 1 463 ? -32.082 -12.566 -9.402 1.00 62.88 ? 436 THR A C 1 ATOM 2963 O O . THR A 1 463 ? -33.061 -12.947 -10.044 1.00 66.40 ? 436 THR A O 1 ATOM 2964 C CB . THR A 1 463 ? -31.758 -14.729 -8.216 1.00 58.98 ? 436 THR A CB 1 ATOM 2965 O OG1 . THR A 1 463 ? -32.438 -14.229 -7.061 1.00 56.86 ? 436 THR A OG1 1 ATOM 2966 C CG2 . THR A 1 463 ? -30.781 -15.829 -7.798 1.00 59.45 ? 436 THR A CG2 1 ATOM 2967 N N . CYS A 1 464 ? -31.905 -11.287 -9.091 1.00 65.87 ? 437 CYS A N 1 ATOM 2968 C CA . CYS A 1 464 ? -32.915 -10.267 -9.429 1.00 67.40 ? 437 CYS A CA 1 ATOM 2969 C C . CYS A 1 464 ? -33.055 -10.109 -10.935 1.00 64.28 ? 437 CYS A C 1 ATOM 2970 O O . CYS A 1 464 ? -32.046 -10.004 -11.635 1.00 65.63 ? 437 CYS A O 1 ATOM 2971 C CB . CYS A 1 464 ? -32.530 -8.906 -8.824 1.00 68.52 ? 437 CYS A CB 1 ATOM 2972 S SG . CYS A 1 464 ? -33.736 -7.564 -9.104 1.00 79.91 ? 437 CYS A SG 1 ATOM 2973 N N . LEU A 1 465 ? -34.296 -10.063 -11.421 1.00 64.63 ? 438 LEU A N 1 ATOM 2974 C CA . LEU A 1 465 ? -34.570 -9.845 -12.850 1.00 64.33 ? 438 LEU A CA 1 ATOM 2975 C C . LEU A 1 465 ? -35.152 -8.452 -13.114 1.00 66.17 ? 438 LEU A C 1 ATOM 2976 O O . LEU A 1 465 ? -36.139 -8.057 -12.472 1.00 63.18 ? 438 LEU A O 1 ATOM 2977 C CB . LEU A 1 465 ? -35.513 -10.923 -13.389 1.00 63.28 ? 438 LEU A CB 1 ATOM 2978 C CG . LEU A 1 465 ? -34.939 -12.343 -13.299 1.00 64.53 ? 438 LEU A CG 1 ATOM 2979 C CD1 . LEU A 1 465 ? -35.987 -13.397 -13.650 1.00 66.81 ? 438 LEU A CD1 1 ATOM 2980 C CD2 . LEU A 1 465 ? -33.702 -12.487 -14.177 1.00 62.04 ? 438 LEU A CD2 1 ATOM 2981 N N . PRO A 1 466 ? -34.541 -7.701 -14.061 1.00 70.41 ? 439 PRO A N 1 ATOM 2982 C CA . PRO A 1 466 ? -34.955 -6.338 -14.412 1.00 71.96 ? 439 PRO A CA 1 ATOM 2983 C C . PRO A 1 466 ? -36.467 -6.165 -14.577 1.00 72.15 ? 439 PRO A C 1 ATOM 2984 O O . PRO A 1 466 ? -37.118 -7.005 -15.196 1.00 78.15 ? 439 PRO A O 1 ATOM 2985 C CB . PRO A 1 466 ? -34.253 -6.098 -15.747 1.00 73.35 ? 439 PRO A CB 1 ATOM 2986 C CG . PRO A 1 466 ? -33.024 -6.937 -15.685 1.00 72.73 ? 439 PRO A CG 1 ATOM 2987 C CD . PRO A 1 466 ? -33.354 -8.126 -14.834 1.00 71.90 ? 439 PRO A CD 1 ATOM 2988 N N . GLY A 1 467 ? -37.009 -5.089 -14.016 1.00 65.28 ? 440 GLY A N 1 ATOM 2989 C CA . GLY A 1 467 ? -38.446 -4.868 -13.975 1.00 61.97 ? 440 GLY A CA 1 ATOM 2990 C C . GLY A 1 467 ? -39.132 -5.524 -12.786 1.00 67.62 ? 440 GLY A C 1 ATOM 2991 O O . GLY A 1 467 ? -40.144 -5.018 -12.287 1.00 72.25 ? 440 GLY A O 1 ATOM 2992 N N . ARG A 1 468 ? -38.586 -6.642 -12.316 1.00 65.08 ? 441 ARG A N 1 ATOM 2993 C CA . ARG A 1 468 ? -39.147 -7.344 -11.168 1.00 65.06 ? 441 ARG A CA 1 ATOM 2994 C C . ARG A 1 468 ? -38.405 -7.002 -9.844 1.00 63.02 ? 441 ARG A C 1 ATOM 2995 O O . ARG A 1 468 ? -38.677 -7.611 -8.812 1.00 60.49 ? 441 ARG A O 1 ATOM 2996 C CB . ARG A 1 468 ? -39.123 -8.854 -11.441 1.00 63.05 ? 441 ARG A CB 1 ATOM 2997 N N . GLY A 1 469 ? -37.477 -6.039 -9.886 1.00 64.31 ? 442 GLY A N 1 ATOM 2998 C CA . GLY A 1 469 ? -36.643 -5.670 -8.733 1.00 67.38 ? 442 GLY A CA 1 ATOM 2999 C C . GLY A 1 469 ? -37.299 -4.708 -7.753 1.00 67.69 ? 442 GLY A C 1 ATOM 3000 O O . GLY A 1 469 ? -38.420 -4.232 -7.978 1.00 62.96 ? 442 GLY A O 1 ATOM 3001 N N . LEU A 1 470 ? -36.596 -4.417 -6.657 1.00 67.54 ? 443 LEU A N 1 ATOM 3002 C CA . LEU A 1 470 ? -37.201 -3.650 -5.557 1.00 61.16 ? 443 LEU A CA 1 ATOM 3003 C C . LEU A 1 470 ? -36.939 -2.156 -5.649 1.00 55.90 ? 443 LEU A C 1 ATOM 3004 O O . LEU A 1 470 ? -37.620 -1.371 -5.003 1.00 59.74 ? 443 LEU A O 1 ATOM 3005 C CB . LEU A 1 470 ? -36.698 -4.165 -4.204 1.00 57.95 ? 443 LEU A CB 1 ATOM 3006 C CG . LEU A 1 470 ? -37.167 -5.545 -3.774 1.00 53.94 ? 443 LEU A CG 1 ATOM 3007 C CD1 . LEU A 1 470 ? -36.447 -5.966 -2.511 1.00 55.17 ? 443 LEU A CD1 1 ATOM 3008 C CD2 . LEU A 1 470 ? -38.673 -5.568 -3.559 1.00 53.52 ? 443 LEU A CD2 1 ATOM 3009 N N . PHE A 1 471 ? -35.956 -1.772 -6.444 1.00 57.50 ? 444 PHE A N 1 ATOM 3010 C CA . PHE A 1 471 ? -35.482 -0.394 -6.491 1.00 62.32 ? 444 PHE A CA 1 ATOM 3011 C C . PHE A 1 471 ? -36.248 0.408 -7.548 1.00 74.36 ? 444 PHE A C 1 ATOM 3012 O O . PHE A 1 471 ? -37.277 -0.059 -8.032 1.00 82.34 ? 444 PHE A O 1 ATOM 3013 C CB . PHE A 1 471 ? -33.964 -0.420 -6.681 1.00 63.10 ? 444 PHE A CB 1 ATOM 3014 C CG . PHE A 1 471 ? -33.274 -1.212 -5.606 1.00 65.29 ? 444 PHE A CG 1 ATOM 3015 C CD1 . PHE A 1 471 ? -33.072 -0.655 -4.350 1.00 61.93 ? 444 PHE A CD1 1 ATOM 3016 C CD2 . PHE A 1 471 ? -32.915 -2.540 -5.810 1.00 64.32 ? 444 PHE A CD2 1 ATOM 3017 C CE1 . PHE A 1 471 ? -32.479 -1.388 -3.336 1.00 63.65 ? 444 PHE A CE1 1 ATOM 3018 C CE2 . PHE A 1 471 ? -32.315 -3.277 -4.797 1.00 67.92 ? 444 PHE A CE2 1 ATOM 3019 C CZ . PHE A 1 471 ? -32.099 -2.699 -3.555 1.00 65.63 ? 444 PHE A CZ 1 ATOM 3020 N N . THR A 1 472 ? -35.796 1.620 -7.868 1.00 82.71 ? 445 THR A N 1 ATOM 3021 C CA . THR A 1 472 ? -36.561 2.517 -8.748 1.00 88.78 ? 445 THR A CA 1 ATOM 3022 C C . THR A 1 472 ? -36.841 1.859 -10.109 1.00 91.96 ? 445 THR A C 1 ATOM 3023 O O . THR A 1 472 ? -35.964 1.214 -10.697 1.00 90.10 ? 445 THR A O 1 ATOM 3024 C CB . THR A 1 472 ? -35.862 3.887 -8.936 1.00 91.86 ? 445 THR A CB 1 ATOM 3025 O OG1 . THR A 1 472 ? -34.455 3.689 -9.110 1.00 95.71 ? 445 THR A OG1 1 ATOM 3026 C CG2 . THR A 1 472 ? -36.098 4.780 -7.716 1.00 92.26 ? 445 THR A CG2 1 ATOM 3027 N N . ASN A 1 473 ? -38.085 1.991 -10.574 1.00 94.79 ? 446 ASN A N 1 ATOM 3028 C CA . ASN A 1 473 ? -38.512 1.459 -11.874 1.00 94.64 ? 446 ASN A CA 1 ATOM 3029 C C . ASN A 1 473 ? -38.306 -0.057 -11.991 1.00 92.31 ? 446 ASN A C 1 ATOM 3030 O O . ASN A 1 473 ? -37.937 -0.562 -13.055 1.00 94.66 ? 446 ASN A O 1 ATOM 3031 C CB . ASN A 1 473 ? -37.777 2.179 -13.025 1.00 93.14 ? 446 ASN A CB 1 ATOM 3032 C CG . ASN A 1 473 ? -38.097 3.663 -13.103 1.00 90.89 ? 446 ASN A CG 1 ATOM 3033 O OD1 . ASN A 1 473 ? -37.216 4.476 -13.394 1.00 82.67 ? 446 ASN A OD1 1 ATOM 3034 N ND2 . ASN A 1 473 ? -39.358 4.025 -12.867 1.00 87.31 ? 446 ASN A ND2 1 ATOM 3035 N N . GLY A 1 474 ? -38.542 -0.775 -10.895 1.00 81.63 ? 447 GLY A N 1 ATOM 3036 C CA . GLY A 1 474 ? -38.286 -2.206 -10.840 1.00 76.11 ? 447 GLY A CA 1 ATOM 3037 C C . GLY A 1 474 ? -36.838 -2.586 -11.127 1.00 74.29 ? 447 GLY A C 1 ATOM 3038 O O . GLY A 1 474 ? -36.579 -3.719 -11.524 1.00 77.87 ? 447 GLY A O 1 ATOM 3039 N N . SER A 1 475 ? -35.895 -1.657 -10.943 1.00 66.41 ? 448 SER A N 1 ATOM 3040 C CA . SER A 1 475 ? -34.478 -1.936 -11.202 1.00 64.19 ? 448 SER A CA 1 ATOM 3041 C C . SER A 1 475 ? -33.888 -2.879 -10.156 1.00 65.33 ? 448 SER A C 1 ATOM 3042 O O . SER A 1 475 ? -34.500 -3.128 -9.109 1.00 62.57 ? 448 SER A O 1 ATOM 3043 C CB . SER A 1 475 ? -33.655 -0.643 -11.239 1.00 62.88 ? 448 SER A CB 1 ATOM 3044 N N . CYS A 1 476 ? -32.701 -3.396 -10.462 1.00 64.60 ? 449 CYS A N 1 ATOM 3045 C CA . CYS A 1 476 ? -31.985 -4.325 -9.605 1.00 67.32 ? 449 CYS A CA 1 ATOM 3046 C C . CYS A 1 476 ? -30.669 -3.706 -9.151 1.00 67.14 ? 449 CYS A C 1 ATOM 3047 O O . CYS A 1 476 ? -30.141 -2.825 -9.811 1.00 69.85 ? 449 CYS A O 1 ATOM 3048 C CB . CYS A 1 476 ? -31.682 -5.625 -10.364 1.00 72.22 ? 449 CYS A CB 1 ATOM 3049 S SG . CYS A 1 476 ? -33.146 -6.600 -10.832 1.00 76.42 ? 449 CYS A SG 1 ATOM 3050 N N . ALA A 1 477 ? -30.139 -4.185 -8.030 1.00 63.57 ? 450 ALA A N 1 ATOM 3051 C CA . ALA A 1 477 ? -28.808 -3.803 -7.570 1.00 61.55 ? 450 ALA A CA 1 ATOM 3052 C C . ALA A 1 477 ? -27.777 -4.683 -8.257 1.00 60.58 ? 450 ALA A C 1 ATOM 3053 O O . ALA A 1 477 ? -28.087 -5.802 -8.625 1.00 63.03 ? 450 ALA A O 1 ATOM 3054 C CB . ALA A 1 477 ? -28.711 -3.965 -6.052 1.00 63.00 ? 450 ALA A CB 1 ATOM 3055 N N . ASP A 1 478 ? -26.551 -4.185 -8.392 1.00 62.60 ? 451 ASP A N 1 ATOM 3056 C CA . ASP A 1 478 ? -25.438 -4.949 -8.934 1.00 63.86 ? 451 ASP A CA 1 ATOM 3057 C C . ASP A 1 478 ? -24.659 -5.627 -7.815 1.00 65.82 ? 451 ASP A C 1 ATOM 3058 O O . ASP A 1 478 ? -24.032 -4.966 -6.995 1.00 69.56 ? 451 ASP A O 1 ATOM 3059 C CB . ASP A 1 478 ? -24.504 -4.023 -9.718 1.00 70.21 ? 451 ASP A CB 1 ATOM 3060 C CG . ASP A 1 478 ? -23.223 -4.717 -10.176 1.00 73.14 ? 451 ASP A CG 1 ATOM 3061 O OD1 . ASP A 1 478 ? -23.128 -5.957 -10.087 1.00 75.89 ? 451 ASP A OD1 1 ATOM 3062 O OD2 . ASP A 1 478 ? -22.295 -4.012 -10.624 1.00 82.82 ? 451 ASP A OD2 1 ATOM 3063 N N . ILE A 1 479 ? -24.652 -6.955 -7.816 1.00 70.16 ? 452 ILE A N 1 ATOM 3064 C CA . ILE A 1 479 ? -24.013 -7.720 -6.746 1.00 70.40 ? 452 ILE A CA 1 ATOM 3065 C C . ILE A 1 479 ? -22.482 -7.615 -6.717 1.00 73.19 ? 452 ILE A C 1 ATOM 3066 O O . ILE A 1 479 ? -21.851 -7.926 -5.702 1.00 73.61 ? 452 ILE A O 1 ATOM 3067 C CB . ILE A 1 479 ? -24.459 -9.200 -6.761 1.00 73.08 ? 452 ILE A CB 1 ATOM 3068 C CG1 . ILE A 1 479 ? -24.047 -9.877 -5.450 1.00 73.81 ? 452 ILE A CG1 1 ATOM 3069 C CG2 . ILE A 1 479 ? -23.908 -9.947 -7.976 1.00 73.91 ? 452 ILE A CG2 1 ATOM 3070 C CD1 . ILE A 1 479 ? -24.911 -11.047 -5.066 1.00 75.12 ? 452 ILE A CD1 1 ATOM 3071 N N . LYS A 1 480 ? -21.887 -7.180 -7.822 1.00 74.91 ? 453 LYS A N 1 ATOM 3072 C CA . LYS A 1 480 ? -20.447 -6.925 -7.865 1.00 75.62 ? 453 LYS A CA 1 ATOM 3073 C C . LYS A 1 480 ? -20.095 -5.611 -7.164 1.00 73.60 ? 453 LYS A C 1 ATOM 3074 O O . LYS A 1 480 ? -18.956 -5.432 -6.737 1.00 71.32 ? 453 LYS A O 1 ATOM 3075 C CB . LYS A 1 480 ? -19.944 -6.911 -9.317 1.00 79.19 ? 453 LYS A CB 1 ATOM 3076 N N . LYS A 1 481 ? -21.067 -4.698 -7.068 1.00 72.75 ? 454 LYS A N 1 ATOM 3077 C CA . LYS A 1 481 ? -20.897 -3.406 -6.395 1.00 68.19 ? 454 LYS A CA 1 ATOM 3078 C C . LYS A 1 481 ? -22.028 -3.149 -5.381 1.00 59.10 ? 454 LYS A C 1 ATOM 3079 O O . LYS A 1 481 ? -22.619 -2.067 -5.359 1.00 56.37 ? 454 LYS A O 1 ATOM 3080 C CB . LYS A 1 481 ? -20.865 -2.282 -7.447 1.00 69.25 ? 454 LYS A CB 1 ATOM 3081 N N . VAL A 1 482 ? -22.326 -4.140 -4.545 1.00 57.73 ? 455 VAL A N 1 ATOM 3082 C CA . VAL A 1 482 ? -23.456 -4.022 -3.600 1.00 59.36 ? 455 VAL A CA 1 ATOM 3083 C C . VAL A 1 482 ? -23.190 -2.935 -2.572 1.00 54.41 ? 455 VAL A C 1 ATOM 3084 O O . VAL A 1 482 ? -22.109 -2.864 -2.000 1.00 50.93 ? 455 VAL A O 1 ATOM 3085 C CB . VAL A 1 482 ? -23.751 -5.281 -2.730 1.00 61.37 ? 455 VAL A CB 1 ATOM 3086 C CG1 . VAL A 1 482 ? -25.255 -5.517 -2.687 1.00 63.89 ? 455 VAL A CG1 1 ATOM 3087 C CG2 . VAL A 1 482 ? -23.032 -6.527 -3.197 1.00 62.19 ? 455 VAL A CG2 1 ATOM 3088 N N . GLU A 1 483 ? -24.206 -2.141 -2.293 1.00 54.98 ? 456 GLU A N 1 ATOM 3089 C CA . GLU A 1 483 ? -24.144 -1.213 -1.176 1.00 53.84 ? 456 GLU A CA 1 ATOM 3090 C C . GLU A 1 483 ? -25.039 -1.700 -0.035 1.00 48.05 ? 456 GLU A C 1 ATOM 3091 O O . GLU A 1 483 ? -26.094 -2.314 -0.258 1.00 45.08 ? 456 GLU A O 1 ATOM 3092 C CB . GLU A 1 483 ? -24.517 0.179 -1.665 1.00 57.93 ? 456 GLU A CB 1 ATOM 3093 C CG . GLU A 1 483 ? -23.454 0.713 -2.613 1.00 62.56 ? 456 GLU A CG 1 ATOM 3094 C CD . GLU A 1 483 ? -23.782 2.060 -3.223 1.00 70.02 ? 456 GLU A CD 1 ATOM 3095 O OE1 . GLU A 1 483 ? -24.950 2.511 -3.148 1.00 72.84 ? 456 GLU A OE1 1 ATOM 3096 O OE2 . GLU A 1 483 ? -22.854 2.664 -3.808 1.00 79.24 ? 456 GLU A OE2 1 ATOM 3097 N N . ALA A 1 484 ? -24.607 -1.407 1.188 1.00 44.40 ? 457 ALA A N 1 ATOM 3098 C CA . ALA A 1 484 ? -25.287 -1.851 2.411 1.00 40.66 ? 457 ALA A CA 1 ATOM 3099 C C . ALA A 1 484 ? -26.769 -1.538 2.385 1.00 34.83 ? 457 ALA A C 1 ATOM 3100 O O . ALA A 1 484 ? -27.594 -2.394 2.701 1.00 33.96 ? 457 ALA A O 1 ATOM 3101 C CB . ALA A 1 484 ? -24.628 -1.218 3.644 1.00 41.20 ? 457 ALA A CB 1 ATOM 3102 N N . TRP A 1 485 ? -27.117 -0.325 1.989 1.00 32.95 ? 458 TRP A N 1 ATOM 3103 C CA . TRP A 1 485 ? -28.519 0.078 1.968 1.00 37.43 ? 458 TRP A CA 1 ATOM 3104 C C . TRP A 1 485 ? -29.416 -0.796 1.069 1.00 41.99 ? 458 TRP A C 1 ATOM 3105 O O . TRP A 1 485 ? -30.636 -0.885 1.288 1.00 36.50 ? 458 TRP A O 1 ATOM 3106 C CB . TRP A 1 485 ? -28.659 1.556 1.593 1.00 38.78 ? 458 TRP A CB 1 ATOM 3107 C CG . TRP A 1 485 ? -28.297 1.888 0.179 1.00 42.99 ? 458 TRP A CG 1 ATOM 3108 C CD1 . TRP A 1 485 ? -27.058 2.202 -0.301 1.00 42.15 ? 458 TRP A CD1 1 ATOM 3109 C CD2 . TRP A 1 485 ? -29.197 1.967 -0.936 1.00 40.71 ? 458 TRP A CD2 1 ATOM 3110 N NE1 . TRP A 1 485 ? -27.130 2.451 -1.648 1.00 44.75 ? 458 TRP A NE1 1 ATOM 3111 C CE2 . TRP A 1 485 ? -28.430 2.312 -2.063 1.00 44.25 ? 458 TRP A CE2 1 ATOM 3112 C CE3 . TRP A 1 485 ? -30.566 1.755 -1.090 1.00 42.45 ? 458 TRP A CE3 1 ATOM 3113 C CZ2 . TRP A 1 485 ? -28.991 2.456 -3.336 1.00 44.65 ? 458 TRP A CZ2 1 ATOM 3114 C CZ3 . TRP A 1 485 ? -31.135 1.898 -2.359 1.00 44.72 ? 458 TRP A CZ3 1 ATOM 3115 C CH2 . TRP A 1 485 ? -30.345 2.249 -3.463 1.00 43.94 ? 458 TRP A CH2 1 ATOM 3116 N N . GLN A 1 486 ? -28.799 -1.442 0.073 1.00 43.03 ? 459 GLN A N 1 ATOM 3117 C CA . GLN A 1 486 ? -29.536 -2.303 -0.854 1.00 41.51 ? 459 GLN A CA 1 ATOM 3118 C C . GLN A 1 486 ? -29.772 -3.631 -0.201 1.00 37.63 ? 459 GLN A C 1 ATOM 3119 O O . GLN A 1 486 ? -30.822 -4.220 -0.368 1.00 38.90 ? 459 GLN A O 1 ATOM 3120 C CB . GLN A 1 486 ? -28.756 -2.502 -2.155 1.00 44.29 ? 459 GLN A CB 1 ATOM 3121 C CG . GLN A 1 486 ? -28.639 -1.231 -2.959 1.00 44.46 ? 459 GLN A CG 1 ATOM 3122 C CD . GLN A 1 486 ? -27.608 -1.313 -4.080 1.00 46.55 ? 459 GLN A CD 1 ATOM 3123 O OE1 . GLN A 1 486 ? -26.556 -1.961 -3.964 1.00 44.04 ? 459 GLN A OE1 1 ATOM 3124 N NE2 . GLN A 1 486 ? -27.891 -0.601 -5.161 1.00 49.35 ? 459 GLN A NE2 1 ATOM 3125 N N . VAL A 1 487 ? -28.789 -4.081 0.569 1.00 36.09 ? 460 VAL A N 1 ATOM 3126 C CA . VAL A 1 487 ? -28.951 -5.278 1.365 1.00 35.15 ? 460 VAL A CA 1 ATOM 3127 C C . VAL A 1 487 ? -30.086 -5.052 2.377 1.00 34.76 ? 460 VAL A C 1 ATOM 3128 O O . VAL A 1 487 ? -30.913 -5.931 2.601 1.00 36.17 ? 460 VAL A O 1 ATOM 3129 C CB . VAL A 1 487 ? -27.632 -5.694 2.054 1.00 35.34 ? 460 VAL A CB 1 ATOM 3130 C CG1 . VAL A 1 487 ? -27.805 -7.008 2.791 1.00 38.53 ? 460 VAL A CG1 1 ATOM 3131 C CG2 . VAL A 1 487 ? -26.511 -5.848 1.035 1.00 36.26 ? 460 VAL A CG2 1 ATOM 3132 N N . LEU A 1 488 ? -30.117 -3.876 3.002 1.00 35.65 ? 461 LEU A N 1 ATOM 3133 C CA . LEU A 1 488 ? -31.181 -3.532 3.969 1.00 34.46 ? 461 LEU A CA 1 ATOM 3134 C C . LEU A 1 488 ? -32.529 -3.637 3.292 1.00 32.74 ? 461 LEU A C 1 ATOM 3135 O O . LEU A 1 488 ? -33.462 -4.261 3.809 1.00 34.90 ? 461 LEU A O 1 ATOM 3136 C CB . LEU A 1 488 ? -30.982 -2.110 4.487 1.00 33.17 ? 461 LEU A CB 1 ATOM 3137 C CG . LEU A 1 488 ? -31.965 -1.589 5.553 1.00 34.36 ? 461 LEU A CG 1 ATOM 3138 C CD1 . LEU A 1 488 ? -32.111 -2.546 6.716 1.00 33.42 ? 461 LEU A CD1 1 ATOM 3139 C CD2 . LEU A 1 488 ? -31.623 -0.191 6.067 1.00 35.15 ? 461 LEU A CD2 1 ATOM 3140 N N . LYS A 1 489 ? -32.623 -3.032 2.120 1.00 32.93 ? 462 LYS A N 1 ATOM 3141 C CA . LYS A 1 489 ? -33.858 -3.077 1.350 1.00 38.00 ? 462 LYS A CA 1 ATOM 3142 C C . LYS A 1 489 ? -34.326 -4.516 1.121 1.00 37.92 ? 462 LYS A C 1 ATOM 3143 O O . LYS A 1 489 ? -35.479 -4.867 1.376 1.00 37.65 ? 462 LYS A O 1 ATOM 3144 C CB . LYS A 1 489 ? -33.657 -2.367 0.022 1.00 40.73 ? 462 LYS A CB 1 ATOM 3145 C CG . LYS A 1 489 ? -34.860 -2.415 -0.890 1.00 42.09 ? 462 LYS A CG 1 ATOM 3146 C CD . LYS A 1 489 ? -36.088 -1.829 -0.231 1.00 42.71 ? 462 LYS A CD 1 ATOM 3147 C CE . LYS A 1 489 ? -37.206 -1.737 -1.247 1.00 45.09 ? 462 LYS A CE 1 ATOM 3148 N NZ . LYS A 1 489 ? -38.351 -0.956 -0.732 1.00 45.13 ? 462 LYS A NZ 1 ATOM 3149 N N . HIS A 1 490 ? -33.399 -5.365 0.714 1.00 38.62 ? 463 HIS A N 1 ATOM 3150 C CA . HIS A 1 490 ? -33.725 -6.759 0.507 1.00 39.53 ? 463 HIS A CA 1 ATOM 3151 C C . HIS A 1 490 ? -34.051 -7.524 1.773 1.00 39.79 ? 463 HIS A C 1 ATOM 3152 O O . HIS A 1 490 ? -34.875 -8.435 1.746 1.00 36.52 ? 463 HIS A O 1 ATOM 3153 C CB . HIS A 1 490 ? -32.608 -7.436 -0.277 1.00 43.50 ? 463 HIS A CB 1 ATOM 3154 C CG . HIS A 1 490 ? -32.773 -7.272 -1.746 1.00 48.59 ? 463 HIS A CG 1 ATOM 3155 N ND1 . HIS A 1 490 ? -33.532 -8.144 -2.493 1.00 47.84 ? 463 HIS A ND1 1 ATOM 3156 C CD2 . HIS A 1 490 ? -32.364 -6.296 -2.591 1.00 50.44 ? 463 HIS A CD2 1 ATOM 3157 C CE1 . HIS A 1 490 ? -33.544 -7.735 -3.746 1.00 51.27 ? 463 HIS A CE1 1 ATOM 3158 N NE2 . HIS A 1 490 ? -32.848 -6.615 -3.833 1.00 50.70 ? 463 HIS A NE2 1 ATOM 3159 N N . LEU A 1 491 ? -33.399 -7.174 2.880 1.00 36.98 ? 464 LEU A N 1 ATOM 3160 C CA . LEU A 1 491 ? -33.711 -7.811 4.142 1.00 32.36 ? 464 LEU A CA 1 ATOM 3161 C C . LEU A 1 491 ? -35.125 -7.437 4.556 1.00 32.67 ? 464 LEU A C 1 ATOM 3162 O O . LEU A 1 491 ? -35.854 -8.267 5.121 1.00 33.56 ? 464 LEU A O 1 ATOM 3163 C CB . LEU A 1 491 ? -32.719 -7.397 5.221 1.00 32.71 ? 464 LEU A CB 1 ATOM 3164 C CG . LEU A 1 491 ? -31.376 -8.082 5.178 1.00 32.07 ? 464 LEU A CG 1 ATOM 3165 C CD1 . LEU A 1 491 ? -30.348 -7.329 5.993 1.00 33.24 ? 464 LEU A CD1 1 ATOM 3166 C CD2 . LEU A 1 491 ? -31.515 -9.496 5.693 1.00 33.42 ? 464 LEU A CD2 1 ATOM 3167 N N . ARG A 1 492 ? -35.523 -6.195 4.306 1.00 33.84 ? 465 ARG A N 1 ATOM 3168 C CA . ARG A 1 492 ? -36.866 -5.757 4.687 1.00 37.75 ? 465 ARG A CA 1 ATOM 3169 C C . ARG A 1 492 ? -37.973 -6.549 3.999 1.00 41.83 ? 465 ARG A C 1 ATOM 3170 O O . ARG A 1 492 ? -39.076 -6.669 4.536 1.00 41.63 ? 465 ARG A O 1 ATOM 3171 C CB . ARG A 1 492 ? -37.062 -4.273 4.379 1.00 39.02 ? 465 ARG A CB 1 ATOM 3172 C CG . ARG A 1 492 ? -36.294 -3.337 5.305 1.00 43.61 ? 465 ARG A CG 1 ATOM 3173 C CD . ARG A 1 492 ? -36.883 -1.954 5.264 1.00 46.06 ? 465 ARG A CD 1 ATOM 3174 N NE . ARG A 1 492 ? -36.072 -0.974 5.980 1.00 49.56 ? 465 ARG A NE 1 ATOM 3175 C CZ . ARG A 1 492 ? -36.127 0.343 5.766 1.00 49.46 ? 465 ARG A CZ 1 ATOM 3176 N NH1 . ARG A 1 492 ? -36.944 0.837 4.845 1.00 46.47 ? 465 ARG A NH1 1 ATOM 3177 N NH2 . ARG A 1 492 ? -35.341 1.166 6.458 1.00 48.69 ? 465 ARG A NH2 1 ATOM 3178 N N . HIS A 1 493 ? -37.686 -7.058 2.805 1.00 44.26 ? 466 HIS A N 1 ATOM 3179 C CA . HIS A 1 493 ? -38.667 -7.822 2.031 1.00 48.17 ? 466 HIS A CA 1 ATOM 3180 C C . HIS A 1 493 ? -38.343 -9.310 1.918 1.00 46.83 ? 466 HIS A C 1 ATOM 3181 O O . HIS A 1 493 ? -38.951 -10.027 1.145 1.00 45.49 ? 466 HIS A O 1 ATOM 3182 C CB . HIS A 1 493 ? -38.804 -7.137 0.671 1.00 51.05 ? 466 HIS A CB 1 ATOM 3183 C CG . HIS A 1 493 ? -39.229 -5.707 0.823 1.00 57.21 ? 466 HIS A CG 1 ATOM 3184 N ND1 . HIS A 1 493 ? -40.233 -5.358 1.705 1.00 61.88 ? 466 HIS A ND1 1 ATOM 3185 C CD2 . HIS A 1 493 ? -38.734 -4.543 0.339 1.00 56.47 ? 466 HIS A CD2 1 ATOM 3186 C CE1 . HIS A 1 493 ? -40.371 -4.048 1.728 1.00 59.97 ? 466 HIS A CE1 1 ATOM 3187 N NE2 . HIS A 1 493 ? -39.479 -3.529 0.904 1.00 62.11 ? 466 HIS A NE2 1 ATOM 3188 N N . LEU A 1 494 ? -37.419 -9.770 2.742 1.00 43.51 ? 467 LEU A N 1 ATOM 3189 C CA . LEU A 1 494 ? -36.921 -11.122 2.649 1.00 44.44 ? 467 LEU A CA 1 ATOM 3190 C C . LEU A 1 494 ? -37.966 -12.140 3.085 1.00 47.61 ? 467 LEU A C 1 ATOM 3191 O O . LEU A 1 494 ? -38.743 -11.898 4.019 1.00 43.90 ? 467 LEU A O 1 ATOM 3192 C CB . LEU A 1 494 ? -35.679 -11.269 3.516 1.00 44.62 ? 467 LEU A CB 1 ATOM 3193 C CG . LEU A 1 494 ? -35.020 -12.639 3.541 1.00 44.25 ? 467 LEU A CG 1 ATOM 3194 C CD1 . LEU A 1 494 ? -34.416 -12.930 2.177 1.00 47.34 ? 467 LEU A CD1 1 ATOM 3195 C CD2 . LEU A 1 494 ? -33.964 -12.713 4.622 1.00 44.55 ? 467 LEU A CD2 1 ATOM 3196 N N . ASN A 1 495 ? -37.987 -13.277 2.383 1.00 47.78 ? 468 ASN A N 1 ATOM 3197 C CA . ASN A 1 495 ? -38.855 -14.388 2.728 1.00 49.13 ? 468 ASN A CA 1 ATOM 3198 C C . ASN A 1 495 ? -38.196 -15.664 2.253 1.00 47.99 ? 468 ASN A C 1 ATOM 3199 O O . ASN A 1 495 ? -38.165 -15.922 1.065 1.00 49.56 ? 468 ASN A O 1 ATOM 3200 C CB . ASN A 1 495 ? -40.217 -14.204 2.063 1.00 51.63 ? 468 ASN A CB 1 ATOM 3201 C CG . ASN A 1 495 ? -41.207 -15.272 2.459 1.00 60.35 ? 468 ASN A CG 1 ATOM 3202 O OD1 . ASN A 1 495 ? -40.858 -16.241 3.125 1.00 65.53 ? 468 ASN A OD1 1 ATOM 3203 N ND2 . ASN A 1 495 ? -42.471 -15.095 2.039 1.00 72.44 ? 468 ASN A ND2 1 ATOM 3204 N N . PHE A 1 496 ? -37.612 -16.432 3.162 1.00 47.28 ? 469 PHE A N 1 ATOM 3205 C CA . PHE A 1 496 ? -36.990 -17.696 2.777 1.00 47.63 ? 469 PHE A CA 1 ATOM 3206 C C . PHE A 1 496 ? -37.391 -18.790 3.728 1.00 50.47 ? 469 PHE A C 1 ATOM 3207 O O . PHE A 1 496 ? -37.956 -18.543 4.811 1.00 48.25 ? 469 PHE A O 1 ATOM 3208 C CB . PHE A 1 496 ? -35.470 -17.587 2.718 1.00 46.25 ? 469 PHE A CB 1 ATOM 3209 C CG . PHE A 1 496 ? -34.802 -17.505 4.071 1.00 48.11 ? 469 PHE A CG 1 ATOM 3210 C CD1 . PHE A 1 496 ? -34.690 -16.293 4.737 1.00 47.12 ? 469 PHE A CD1 1 ATOM 3211 C CD2 . PHE A 1 496 ? -34.273 -18.640 4.670 1.00 49.59 ? 469 PHE A CD2 1 ATOM 3212 C CE1 . PHE A 1 496 ? -34.070 -16.206 5.974 1.00 47.07 ? 469 PHE A CE1 1 ATOM 3213 C CE2 . PHE A 1 496 ? -33.656 -18.564 5.909 1.00 51.80 ? 469 PHE A CE2 1 ATOM 3214 C CZ . PHE A 1 496 ? -33.554 -17.338 6.559 1.00 50.17 ? 469 PHE A CZ 1 ATOM 3215 N N . THR A 1 497 ? -37.111 -20.016 3.319 1.00 51.54 ? 470 THR A N 1 ATOM 3216 C CA . THR A 1 497 ? -37.476 -21.141 4.147 1.00 53.67 ? 470 THR A CA 1 ATOM 3217 C C . THR A 1 497 ? -36.206 -21.688 4.743 1.00 52.47 ? 470 THR A C 1 ATOM 3218 O O . THR A 1 497 ? -35.217 -21.847 4.055 1.00 58.86 ? 470 THR A O 1 ATOM 3219 C CB . THR A 1 497 ? -38.365 -22.172 3.443 1.00 55.59 ? 470 THR A CB 1 ATOM 3220 O OG1 . THR A 1 497 ? -37.871 -23.482 3.720 1.00 64.51 ? 470 THR A OG1 1 ATOM 3221 C CG2 . THR A 1 497 ? -38.460 -21.908 1.951 1.00 55.81 ? 470 THR A CG2 1 ATOM 3222 N N . ASN A 1 498 ? -36.227 -21.909 6.045 1.00 55.84 ? 471 ASN A N 1 ATOM 3223 C CA . ASN A 1 498 ? -35.035 -22.339 6.747 1.00 60.86 ? 471 ASN A CA 1 ATOM 3224 C C . ASN A 1 498 ? -34.965 -23.861 6.813 1.00 61.91 ? 471 ASN A C 1 ATOM 3225 O O . ASN A 1 498 ? -35.934 -24.555 6.485 1.00 61.35 ? 471 ASN A O 1 ATOM 3226 C CB . ASN A 1 498 ? -34.946 -21.686 8.148 1.00 63.14 ? 471 ASN A CB 1 ATOM 3227 C CG . ASN A 1 498 ? -36.060 -22.123 9.111 1.00 65.35 ? 471 ASN A CG 1 ATOM 3228 O OD1 . ASN A 1 498 ? -36.707 -23.151 8.936 1.00 61.77 ? 471 ASN A OD1 1 ATOM 3229 N ND2 . ASN A 1 498 ? -36.270 -21.322 10.151 1.00 67.58 ? 471 ASN A ND2 1 ATOM 3230 N N . ASN A 1 499 ? -33.804 -24.356 7.231 1.00 62.49 ? 472 ASN A N 1 ATOM 3231 C CA . ASN A 1 499 ? -33.533 -25.793 7.367 1.00 61.10 ? 472 ASN A CA 1 ATOM 3232 C C . ASN A 1 499 ? -34.532 -26.542 8.249 1.00 66.16 ? 472 ASN A C 1 ATOM 3233 O O . ASN A 1 499 ? -34.659 -27.746 8.137 1.00 68.34 ? 472 ASN A O 1 ATOM 3234 C CB . ASN A 1 499 ? -32.106 -26.027 7.885 1.00 60.47 ? 472 ASN A CB 1 ATOM 3235 C CG . ASN A 1 499 ? -31.876 -25.430 9.275 1.00 63.80 ? 472 ASN A CG 1 ATOM 3236 O OD1 . ASN A 1 499 ? -31.959 -24.209 9.461 1.00 69.19 ? 472 ASN A OD1 1 ATOM 3237 N ND2 . ASN A 1 499 ? -31.602 -26.284 10.254 1.00 55.79 ? 472 ASN A ND2 1 ATOM 3238 N N . MET A 1 500 ? -35.250 -25.835 9.114 1.00 69.33 ? 473 MET A N 1 ATOM 3239 C CA . MET A 1 500 ? -36.290 -26.459 9.920 1.00 67.38 ? 473 MET A CA 1 ATOM 3240 C C . MET A 1 500 ? -37.645 -26.478 9.185 1.00 65.73 ? 473 MET A C 1 ATOM 3241 O O . MET A 1 500 ? -38.661 -26.824 9.786 1.00 64.20 ? 473 MET A O 1 ATOM 3242 C CB . MET A 1 500 ? -36.433 -25.726 11.271 1.00 70.10 ? 473 MET A CB 1 ATOM 3243 C CG . MET A 1 500 ? -36.536 -26.645 12.467 1.00 73.33 ? 473 MET A CG 1 ATOM 3244 S SD . MET A 1 500 ? -34.924 -27.106 13.120 1.00 77.79 ? 473 MET A SD 1 ATOM 3245 C CE . MET A 1 500 ? -34.201 -28.083 11.807 1.00 82.28 ? 473 MET A CE 1 ATOM 3246 N N . GLY A 1 501 ? -37.669 -26.097 7.907 1.00 68.47 ? 474 GLY A N 1 ATOM 3247 C CA . GLY A 1 501 ? -38.922 -26.016 7.129 1.00 73.57 ? 474 GLY A CA 1 ATOM 3248 C C . GLY A 1 501 ? -39.832 -24.817 7.418 1.00 72.52 ? 474 GLY A C 1 ATOM 3249 O O . GLY A 1 501 ? -40.975 -24.779 6.962 1.00 70.66 ? 474 GLY A O 1 ATOM 3250 N N . GLU A 1 502 ? -39.327 -23.830 8.153 1.00 71.91 ? 475 GLU A N 1 ATOM 3251 C CA . GLU A 1 502 ? -40.106 -22.644 8.513 1.00 72.43 ? 475 GLU A CA 1 ATOM 3252 C C . GLU A 1 502 ? -39.773 -21.460 7.599 1.00 65.47 ? 475 GLU A C 1 ATOM 3253 O O . GLU A 1 502 ? -38.619 -21.284 7.206 1.00 62.65 ? 475 GLU A O 1 ATOM 3254 C CB . GLU A 1 502 ? -39.808 -22.242 9.957 1.00 77.01 ? 475 GLU A CB 1 ATOM 3255 C CG . GLU A 1 502 ? -40.968 -21.578 10.669 1.00 82.35 ? 475 GLU A CG 1 ATOM 3256 C CD . GLU A 1 502 ? -41.994 -22.559 11.188 1.00 85.45 ? 475 GLU A CD 1 ATOM 3257 O OE1 . GLU A 1 502 ? -42.660 -22.216 12.186 1.00 92.89 ? 475 GLU A OE1 1 ATOM 3258 O OE2 . GLU A 1 502 ? -42.139 -23.658 10.610 1.00 85.17 ? 475 GLU A OE2 1 ATOM 3259 N N . GLN A 1 503 ? -40.788 -20.662 7.269 1.00 61.19 ? 476 GLN A N 1 ATOM 3260 C CA . GLN A 1 503 ? -40.590 -19.410 6.541 1.00 60.12 ? 476 GLN A CA 1 ATOM 3261 C C . GLN A 1 503 ? -40.024 -18.352 7.484 1.00 55.51 ? 476 GLN A C 1 ATOM 3262 O O . GLN A 1 503 ? -40.513 -18.174 8.593 1.00 49.08 ? 476 GLN A O 1 ATOM 3263 C CB . GLN A 1 503 ? -41.901 -18.888 5.936 1.00 61.22 ? 476 GLN A CB 1 ATOM 3264 C CG . GLN A 1 503 ? -42.454 -19.725 4.788 1.00 64.70 ? 476 GLN A CG 1 ATOM 3265 C CD . GLN A 1 503 ? -41.443 -19.969 3.672 1.00 66.25 ? 476 GLN A CD 1 ATOM 3266 O OE1 . GLN A 1 503 ? -41.006 -21.099 3.465 1.00 64.41 ? 476 GLN A OE1 1 ATOM 3267 N NE2 . GLN A 1 503 ? -41.056 -18.917 2.963 1.00 67.41 ? 476 GLN A NE2 1 ATOM 3268 N N . VAL A 1 504 ? -38.974 -17.665 7.047 1.00 52.11 ? 477 VAL A N 1 ATOM 3269 C CA . VAL A 1 504 ? -38.411 -16.569 7.818 1.00 47.69 ? 477 VAL A CA 1 ATOM 3270 C C . VAL A 1 504 ? -38.658 -15.275 7.074 1.00 45.89 ? 477 VAL A C 1 ATOM 3271 O O . VAL A 1 504 ? -38.210 -15.110 5.931 1.00 44.01 ? 477 VAL A O 1 ATOM 3272 C CB . VAL A 1 504 ? -36.912 -16.752 8.043 1.00 51.46 ? 477 VAL A CB 1 ATOM 3273 C CG1 . VAL A 1 504 ? -36.339 -15.548 8.769 1.00 51.23 ? 477 VAL A CG1 1 ATOM 3274 C CG2 . VAL A 1 504 ? -36.661 -18.030 8.830 1.00 50.28 ? 477 VAL A CG2 1 ATOM 3275 N N . THR A 1 505 ? -39.422 -14.389 7.713 1.00 41.55 ? 478 THR A N 1 ATOM 3276 C CA . THR A 1 505 ? -39.673 -13.033 7.222 1.00 45.17 ? 478 THR A CA 1 ATOM 3277 C C . THR A 1 505 ? -39.675 -12.101 8.403 1.00 40.63 ? 478 THR A C 1 ATOM 3278 O O . THR A 1 505 ? -39.923 -12.522 9.521 1.00 42.75 ? 478 THR A O 1 ATOM 3279 C CB . THR A 1 505 ? -41.072 -12.881 6.578 1.00 47.60 ? 478 THR A CB 1 ATOM 3280 O OG1 . THR A 1 505 ? -42.081 -13.260 7.528 1.00 48.69 ? 478 THR A OG1 1 ATOM 3281 C CG2 . THR A 1 505 ? -41.217 -13.747 5.369 1.00 51.91 ? 478 THR A CG2 1 ATOM 3282 N N . PHE A 1 506 ? -39.458 -10.829 8.128 1.00 38.87 ? 479 PHE A N 1 ATOM 3283 C CA . PHE A 1 506 ? -39.467 -9.800 9.139 1.00 38.75 ? 479 PHE A CA 1 ATOM 3284 C C . PHE A 1 506 ? -40.661 -8.892 8.896 1.00 38.71 ? 479 PHE A C 1 ATOM 3285 O O . PHE A 1 506 ? -40.955 -8.556 7.760 1.00 40.22 ? 479 PHE A O 1 ATOM 3286 C CB . PHE A 1 506 ? -38.161 -8.995 9.068 1.00 37.74 ? 479 PHE A CB 1 ATOM 3287 C CG . PHE A 1 506 ? -36.926 -9.840 9.211 1.00 36.16 ? 479 PHE A CG 1 ATOM 3288 C CD1 . PHE A 1 506 ? -36.558 -10.347 10.447 1.00 34.83 ? 479 PHE A CD1 1 ATOM 3289 C CD2 . PHE A 1 506 ? -36.154 -10.160 8.109 1.00 37.09 ? 479 PHE A CD2 1 ATOM 3290 C CE1 . PHE A 1 506 ? -35.428 -11.136 10.597 1.00 35.55 ? 479 PHE A CE1 1 ATOM 3291 C CE2 . PHE A 1 506 ? -35.011 -10.940 8.246 1.00 39.21 ? 479 PHE A CE2 1 ATOM 3292 C CZ . PHE A 1 506 ? -34.650 -11.443 9.492 1.00 38.26 ? 479 PHE A CZ 1 ATOM 3293 N N . ASP A 1 507 ? -41.341 -8.466 9.964 1.00 37.68 ? 480 ASP A N 1 ATOM 3294 C CA . ASP A 1 507 ? -42.480 -7.562 9.808 1.00 37.25 ? 480 ASP A CA 1 ATOM 3295 C C . ASP A 1 507 ? -41.996 -6.141 9.525 1.00 37.49 ? 480 ASP A C 1 ATOM 3296 O O . ASP A 1 507 ? -40.772 -5.897 9.393 1.00 36.50 ? 480 ASP A O 1 ATOM 3297 C CB . ASP A 1 507 ? -43.438 -7.643 11.016 1.00 39.10 ? 480 ASP A CB 1 ATOM 3298 C CG . ASP A 1 507 ? -42.832 -7.095 12.326 1.00 41.57 ? 480 ASP A CG 1 ATOM 3299 O OD1 . ASP A 1 507 ? -41.818 -6.341 12.315 1.00 40.08 ? 480 ASP A OD1 1 ATOM 3300 O OD2 . ASP A 1 507 ? -43.388 -7.443 13.381 1.00 40.20 ? 480 ASP A OD2 1 ATOM 3301 N N . GLU A 1 508 ? -42.941 -5.207 9.418 1.00 37.82 ? 481 GLU A N 1 ATOM 3302 C CA . GLU A 1 508 ? -42.605 -3.802 9.135 1.00 41.28 ? 481 GLU A CA 1 ATOM 3303 C C . GLU A 1 508 ? -41.709 -3.137 10.214 1.00 40.12 ? 481 GLU A C 1 ATOM 3304 O O . GLU A 1 508 ? -41.079 -2.132 9.926 1.00 37.66 ? 481 GLU A O 1 ATOM 3305 C CB . GLU A 1 508 ? -43.865 -2.969 8.912 1.00 48.64 ? 481 GLU A CB 1 ATOM 3306 C CG . GLU A 1 508 ? -44.839 -2.954 10.077 1.00 56.64 ? 481 GLU A CG 1 ATOM 3307 C CD . GLU A 1 508 ? -46.032 -3.886 9.884 1.00 65.68 ? 481 GLU A CD 1 ATOM 3308 O OE1 . GLU A 1 508 ? -47.147 -3.354 9.644 1.00 71.49 ? 481 GLU A OE1 1 ATOM 3309 O OE2 . GLU A 1 508 ? -45.857 -5.137 9.970 1.00 64.13 ? 481 GLU A OE2 1 HETATM 3310 N N . CSO A 1 509 ? -41.653 -3.701 11.432 1.00 35.79 ? 482 CSO A N 1 HETATM 3311 C CA . CSO A 1 509 ? -40.769 -3.208 12.493 1.00 35.46 ? 482 CSO A CA 1 HETATM 3312 C CB . CSO A 1 509 ? -41.481 -3.319 13.846 1.00 38.60 ? 482 CSO A CB 1 HETATM 3313 S SG . CSO A 1 509 ? -42.882 -2.240 13.864 1.00 45.24 ? 482 CSO A SG 1 HETATM 3314 C C . CSO A 1 509 ? -39.454 -3.934 12.547 1.00 33.87 ? 482 CSO A C 1 HETATM 3315 O O . CSO A 1 509 ? -38.647 -3.674 13.423 1.00 32.85 ? 482 CSO A O 1 HETATM 3316 O OD . CSO A 1 509 ? -44.162 -3.423 13.620 1.00 53.88 ? 482 CSO A OD 1 ATOM 3317 N N . GLY A 1 510 ? -39.189 -4.831 11.597 1.00 34.96 ? 483 GLY A N 1 ATOM 3318 C CA . GLY A 1 510 ? -37.938 -5.607 11.599 1.00 30.68 ? 483 GLY A CA 1 ATOM 3319 C C . GLY A 1 510 ? -37.945 -6.785 12.556 1.00 32.24 ? 483 GLY A C 1 ATOM 3320 O O . GLY A 1 510 ? -36.898 -7.361 12.827 1.00 29.37 ? 483 GLY A O 1 ATOM 3321 N N . ASP A 1 511 ? -39.133 -7.158 13.040 1.00 32.11 ? 484 ASP A N 1 ATOM 3322 C CA . ASP A 1 511 ? -39.284 -8.214 14.030 1.00 35.48 ? 484 ASP A CA 1 ATOM 3323 C C . ASP A 1 511 ? -39.709 -9.583 13.442 1.00 40.72 ? 484 ASP A C 1 ATOM 3324 O O . ASP A 1 511 ? -40.338 -9.665 12.391 1.00 38.97 ? 484 ASP A O 1 ATOM 3325 C CB . ASP A 1 511 ? -40.340 -7.804 15.059 1.00 37.15 ? 484 ASP A CB 1 ATOM 3326 C CG . ASP A 1 511 ? -39.898 -6.608 15.929 1.00 39.07 ? 484 ASP A CG 1 ATOM 3327 O OD1 . ASP A 1 511 ? -38.675 -6.412 16.132 1.00 37.58 ? 484 ASP A OD1 1 ATOM 3328 O OD2 . ASP A 1 511 ? -40.790 -5.881 16.418 1.00 38.46 ? 484 ASP A OD2 1 ATOM 3329 N N . LEU A 1 512 ? -39.305 -10.634 14.145 1.00 43.22 ? 485 LEU A N 1 ATOM 3330 C CA . LEU A 1 512 ? -39.636 -12.014 13.858 1.00 48.55 ? 485 LEU A CA 1 ATOM 3331 C C . LEU A 1 512 ? -40.532 -12.502 15.020 1.00 48.24 ? 485 LEU A C 1 ATOM 3332 O O . LEU A 1 512 ? -40.302 -12.170 16.191 1.00 45.63 ? 485 LEU A O 1 ATOM 3333 C CB . LEU A 1 512 ? -38.317 -12.822 13.680 1.00 50.73 ? 485 LEU A CB 1 ATOM 3334 C CG . LEU A 1 512 ? -38.381 -14.269 13.202 1.00 56.77 ? 485 LEU A CG 1 ATOM 3335 C CD1 . LEU A 1 512 ? -39.012 -14.356 11.821 1.00 62.46 ? 485 LEU A CD1 1 ATOM 3336 C CD2 . LEU A 1 512 ? -37.005 -14.923 13.149 1.00 60.24 ? 485 LEU A CD2 1 ATOM 3337 N N . VAL A 1 513 ? -41.593 -13.228 14.679 1.00 46.92 ? 486 VAL A N 1 ATOM 3338 C CA . VAL A 1 513 ? -42.533 -13.807 15.658 1.00 43.81 ? 486 VAL A CA 1 ATOM 3339 C C . VAL A 1 513 ? -42.030 -15.155 16.158 1.00 40.17 ? 486 VAL A C 1 ATOM 3340 O O . VAL A 1 513 ? -41.423 -15.897 15.416 1.00 39.00 ? 486 VAL A O 1 ATOM 3341 C CB . VAL A 1 513 ? -43.938 -14.058 15.047 1.00 50.46 ? 486 VAL A CB 1 ATOM 3342 C CG1 . VAL A 1 513 ? -44.975 -14.293 16.145 1.00 50.03 ? 486 VAL A CG1 1 ATOM 3343 C CG2 . VAL A 1 513 ? -44.396 -12.903 14.154 1.00 53.52 ? 486 VAL A CG2 1 ATOM 3344 N N . GLY A 1 514 ? -42.298 -15.485 17.414 1.00 39.03 ? 487 GLY A N 1 ATOM 3345 C CA . GLY A 1 514 ? -41.907 -16.778 17.949 1.00 40.59 ? 487 GLY A CA 1 ATOM 3346 C C . GLY A 1 514 ? -42.758 -17.121 19.141 1.00 42.38 ? 487 GLY A C 1 ATOM 3347 O O . GLY A 1 514 ? -43.274 -16.220 19.790 1.00 44.80 ? 487 GLY A O 1 ATOM 3348 N N . ASN A 1 515 ? -42.924 -18.420 19.396 1.00 41.60 ? 488 ASN A N 1 ATOM 3349 C CA . ASN A 1 515 ? -43.631 -18.909 20.581 1.00 44.54 ? 488 ASN A CA 1 ATOM 3350 C C . ASN A 1 515 ? -42.615 -19.121 21.700 1.00 42.91 ? 488 ASN A C 1 ATOM 3351 O O . ASN A 1 515 ? -41.410 -19.007 21.483 1.00 46.14 ? 488 ASN A O 1 ATOM 3352 C CB . ASN A 1 515 ? -44.340 -20.249 20.324 1.00 45.13 ? 488 ASN A CB 1 ATOM 3353 C CG . ASN A 1 515 ? -45.503 -20.147 19.347 1.00 44.26 ? 488 ASN A CG 1 ATOM 3354 O OD1 . ASN A 1 515 ? -46.279 -19.191 19.371 1.00 47.26 ? 488 ASN A OD1 1 ATOM 3355 N ND2 . ASN A 1 515 ? -45.637 -21.179 18.490 1.00 53.19 ? 488 ASN A ND2 1 ATOM 3356 N N . TYR A 1 516 ? -43.099 -19.450 22.889 1.00 40.38 ? 489 TYR A N 1 ATOM 3357 C CA . TYR A 1 516 ? -42.215 -19.824 23.979 1.00 41.48 ? 489 TYR A CA 1 ATOM 3358 C C . TYR A 1 516 ? -42.625 -21.156 24.602 1.00 40.15 ? 489 TYR A C 1 ATOM 3359 O O . TYR A 1 516 ? -43.807 -21.507 24.672 1.00 38.91 ? 489 TYR A O 1 ATOM 3360 C CB . TYR A 1 516 ? -42.213 -18.738 25.080 1.00 41.03 ? 489 TYR A CB 1 ATOM 3361 C CG . TYR A 1 516 ? -41.812 -17.344 24.633 1.00 39.82 ? 489 TYR A CG 1 ATOM 3362 C CD1 . TYR A 1 516 ? -40.473 -16.964 24.533 1.00 39.59 ? 489 TYR A CD1 1 ATOM 3363 C CD2 . TYR A 1 516 ? -42.784 -16.403 24.330 1.00 41.75 ? 489 TYR A CD2 1 ATOM 3364 C CE1 . TYR A 1 516 ? -40.127 -15.678 24.127 1.00 40.21 ? 489 TYR A CE1 1 ATOM 3365 C CE2 . TYR A 1 516 ? -42.458 -15.127 23.921 1.00 42.22 ? 489 TYR A CE2 1 ATOM 3366 C CZ . TYR A 1 516 ? -41.125 -14.764 23.822 1.00 42.26 ? 489 TYR A CZ 1 ATOM 3367 O OH . TYR A 1 516 ? -40.819 -13.475 23.440 1.00 47.60 ? 489 TYR A OH 1 ATOM 3368 N N . SER A 1 517 ? -41.617 -21.859 25.082 1.00 40.52 ? 490 SER A N 1 ATOM 3369 C CA . SER A 1 517 ? -41.774 -22.946 26.023 1.00 40.26 ? 490 SER A CA 1 ATOM 3370 C C . SER A 1 517 ? -41.729 -22.322 27.401 1.00 39.02 ? 490 SER A C 1 ATOM 3371 O O . SER A 1 517 ? -41.047 -21.306 27.609 1.00 34.67 ? 490 SER A O 1 ATOM 3372 C CB . SER A 1 517 ? -40.587 -23.888 25.876 1.00 40.75 ? 490 SER A CB 1 ATOM 3373 O OG . SER A 1 517 ? -40.545 -24.842 26.911 1.00 52.27 ? 490 SER A OG 1 ATOM 3374 N N . ILE A 1 518 ? -42.448 -22.926 28.341 1.00 35.14 ? 491 ILE A N 1 ATOM 3375 C CA . ILE A 1 518 ? -42.392 -22.495 29.727 1.00 35.98 ? 491 ILE A CA 1 ATOM 3376 C C . ILE A 1 518 ? -41.685 -23.584 30.483 1.00 38.42 ? 491 ILE A C 1 ATOM 3377 O O . ILE A 1 518 ? -42.071 -24.747 30.401 1.00 45.25 ? 491 ILE A O 1 ATOM 3378 C CB . ILE A 1 518 ? -43.774 -22.228 30.320 1.00 36.50 ? 491 ILE A CB 1 ATOM 3379 C CG1 . ILE A 1 518 ? -44.476 -21.135 29.529 1.00 38.00 ? 491 ILE A CG1 1 ATOM 3380 C CG2 . ILE A 1 518 ? -43.660 -21.808 31.776 1.00 35.77 ? 491 ILE A CG2 1 ATOM 3381 C CD1 . ILE A 1 518 ? -45.953 -21.007 29.823 1.00 41.97 ? 491 ILE A CD1 1 ATOM 3382 N N . ILE A 1 519 ? -40.640 -23.206 31.200 1.00 36.89 ? 492 ILE A N 1 ATOM 3383 C CA . ILE A 1 519 ? -39.791 -24.159 31.869 1.00 36.69 ? 492 ILE A CA 1 ATOM 3384 C C . ILE A 1 519 ? -39.775 -23.916 33.368 1.00 36.51 ? 492 ILE A C 1 ATOM 3385 O O . ILE A 1 519 ? -40.141 -22.839 33.834 1.00 35.90 ? 492 ILE A O 1 ATOM 3386 C CB . ILE A 1 519 ? -38.346 -24.135 31.309 1.00 36.88 ? 492 ILE A CB 1 ATOM 3387 C CG1 . ILE A 1 519 ? -37.722 -22.739 31.427 1.00 38.49 ? 492 ILE A CG1 1 ATOM 3388 C CG2 . ILE A 1 519 ? -38.348 -24.626 29.855 1.00 35.70 ? 492 ILE A CG2 1 ATOM 3389 C CD1 . ILE A 1 519 ? -36.218 -22.715 31.281 1.00 38.80 ? 492 ILE A CD1 1 ATOM 3390 N N . ASN A 1 520 ? -39.336 -24.926 34.109 1.00 36.99 ? 493 ASN A N 1 ATOM 3391 C CA . ASN A 1 520 ? -39.415 -24.931 35.576 1.00 38.78 ? 493 ASN A CA 1 ATOM 3392 C C . ASN A 1 520 ? -38.161 -25.590 36.094 1.00 37.63 ? 493 ASN A C 1 ATOM 3393 O O . ASN A 1 520 ? -37.718 -26.605 35.567 1.00 43.25 ? 493 ASN A O 1 ATOM 3394 C CB . ASN A 1 520 ? -40.674 -25.684 36.012 1.00 39.15 ? 493 ASN A CB 1 ATOM 3395 C CG . ASN A 1 520 ? -40.941 -25.626 37.509 1.00 42.38 ? 493 ASN A CG 1 ATOM 3396 O OD1 . ASN A 1 520 ? -40.657 -24.643 38.206 1.00 47.71 ? 493 ASN A OD1 1 ATOM 3397 N ND2 . ASN A 1 520 ? -41.546 -26.668 37.999 1.00 42.85 ? 493 ASN A ND2 1 ATOM 3398 N N . TRP A 1 521 ? -37.545 -24.986 37.090 1.00 38.87 ? 494 TRP A N 1 ATOM 3399 C CA . TRP A 1 521 ? -36.207 -25.396 37.509 1.00 40.18 ? 494 TRP A CA 1 ATOM 3400 C C . TRP A 1 521 ? -36.306 -26.548 38.506 1.00 45.00 ? 494 TRP A C 1 ATOM 3401 O O . TRP A 1 521 ? -36.736 -26.344 39.653 1.00 44.31 ? 494 TRP A O 1 ATOM 3402 C CB . TRP A 1 521 ? -35.449 -24.214 38.134 1.00 37.81 ? 494 TRP A CB 1 ATOM 3403 C CG . TRP A 1 521 ? -34.981 -23.186 37.149 1.00 38.28 ? 494 TRP A CG 1 ATOM 3404 C CD1 . TRP A 1 521 ? -35.442 -23.000 35.883 1.00 36.00 ? 494 TRP A CD1 1 ATOM 3405 C CD2 . TRP A 1 521 ? -33.951 -22.197 37.354 1.00 36.73 ? 494 TRP A CD2 1 ATOM 3406 N NE1 . TRP A 1 521 ? -34.751 -21.968 35.285 1.00 39.30 ? 494 TRP A NE1 1 ATOM 3407 C CE2 . TRP A 1 521 ? -33.836 -21.461 36.167 1.00 37.45 ? 494 TRP A CE2 1 ATOM 3408 C CE3 . TRP A 1 521 ? -33.115 -21.880 38.421 1.00 39.79 ? 494 TRP A CE3 1 ATOM 3409 C CZ2 . TRP A 1 521 ? -32.920 -20.413 36.013 1.00 40.76 ? 494 TRP A CZ2 1 ATOM 3410 C CZ3 . TRP A 1 521 ? -32.194 -20.828 38.274 1.00 42.27 ? 494 TRP A CZ3 1 ATOM 3411 C CH2 . TRP A 1 521 ? -32.105 -20.114 37.070 1.00 41.28 ? 494 TRP A CH2 1 ATOM 3412 N N . HIS A 1 522 ? -35.912 -27.744 38.051 1.00 49.52 ? 495 HIS A N 1 ATOM 3413 C CA . HIS A 1 522 ? -35.829 -28.951 38.884 1.00 53.70 ? 495 HIS A CA 1 ATOM 3414 C C . HIS A 1 522 ? -34.364 -29.280 39.197 1.00 52.83 ? 495 HIS A C 1 ATOM 3415 O O . HIS A 1 522 ? -33.447 -28.802 38.538 1.00 50.27 ? 495 HIS A O 1 ATOM 3416 C CB . HIS A 1 522 ? -36.425 -30.163 38.143 1.00 53.13 ? 495 HIS A CB 1 ATOM 3417 C CG . HIS A 1 522 ? -37.907 -30.107 37.917 1.00 56.20 ? 495 HIS A CG 1 ATOM 3418 N ND1 . HIS A 1 522 ? -38.687 -29.008 38.221 1.00 59.88 ? 495 HIS A ND1 1 ATOM 3419 C CD2 . HIS A 1 522 ? -38.747 -31.016 37.364 1.00 57.49 ? 495 HIS A CD2 1 ATOM 3420 C CE1 . HIS A 1 522 ? -39.944 -29.256 37.892 1.00 59.23 ? 495 HIS A CE1 1 ATOM 3421 N NE2 . HIS A 1 522 ? -40.007 -30.464 37.365 1.00 61.10 ? 495 HIS A NE2 1 ATOM 3422 N N . LEU A 1 523 ? -34.169 -30.154 40.178 1.00 58.67 ? 496 LEU A N 1 ATOM 3423 C CA . LEU A 1 523 ? -32.853 -30.686 40.531 1.00 60.25 ? 496 LEU A CA 1 ATOM 3424 C C . LEU A 1 523 ? -32.748 -32.098 39.954 1.00 64.88 ? 496 LEU A C 1 ATOM 3425 O O . LEU A 1 523 ? -33.689 -32.870 40.078 1.00 68.03 ? 496 LEU A O 1 ATOM 3426 C CB . LEU A 1 523 ? -32.724 -30.758 42.048 1.00 62.28 ? 496 LEU A CB 1 ATOM 3427 C CG . LEU A 1 523 ? -31.560 -30.061 42.745 1.00 62.24 ? 496 LEU A CG 1 ATOM 3428 C CD1 . LEU A 1 523 ? -31.413 -30.630 44.144 1.00 59.33 ? 496 LEU A CD1 1 ATOM 3429 C CD2 . LEU A 1 523 ? -30.245 -30.171 42.002 1.00 65.68 ? 496 LEU A CD2 1 ATOM 3430 N N . SER A 1 524 ? -31.626 -32.440 39.324 1.00 67.80 ? 497 SER A N 1 ATOM 3431 C CA . SER A 1 524 ? -31.430 -33.793 38.792 1.00 73.31 ? 497 SER A CA 1 ATOM 3432 C C . SER A 1 524 ? -31.175 -34.778 39.945 1.00 74.68 ? 497 SER A C 1 ATOM 3433 O O . SER A 1 524 ? -30.302 -34.541 40.783 1.00 71.52 ? 497 SER A O 1 ATOM 3434 C CB . SER A 1 524 ? -30.254 -33.834 37.808 1.00 73.97 ? 497 SER A CB 1 ATOM 3435 O OG . SER A 1 524 ? -30.157 -35.091 37.156 1.00 74.65 ? 497 SER A OG 1 ATOM 3436 N N . PRO A 1 525 ? -31.949 -35.876 40.003 1.00 77.83 ? 498 PRO A N 1 ATOM 3437 C CA . PRO A 1 525 ? -31.677 -36.884 41.035 1.00 80.95 ? 498 PRO A CA 1 ATOM 3438 C C . PRO A 1 525 ? -30.372 -37.645 40.753 1.00 80.54 ? 498 PRO A C 1 ATOM 3439 O O . PRO A 1 525 ? -29.659 -38.008 41.688 1.00 81.65 ? 498 PRO A O 1 ATOM 3440 C CB . PRO A 1 525 ? -32.901 -37.800 40.966 1.00 80.83 ? 498 PRO A CB 1 ATOM 3441 C CG . PRO A 1 525 ? -33.397 -37.673 39.558 1.00 82.09 ? 498 PRO A CG 1 ATOM 3442 C CD . PRO A 1 525 ? -33.026 -36.292 39.082 1.00 79.69 ? 498 PRO A CD 1 ATOM 3443 N N . GLU A 1 526 ? -30.056 -37.851 39.473 1.00 81.74 ? 499 GLU A N 1 ATOM 3444 C CA . GLU A 1 526 ? -28.775 -38.445 39.068 1.00 84.54 ? 499 GLU A CA 1 ATOM 3445 C C . GLU A 1 526 ? -27.622 -37.495 39.369 1.00 84.17 ? 499 GLU A C 1 ATOM 3446 O O . GLU A 1 526 ? -26.666 -37.836 40.064 1.00 79.43 ? 499 GLU A O 1 ATOM 3447 C CB . GLU A 1 526 ? -28.722 -38.737 37.551 1.00 84.99 ? 499 GLU A CB 1 ATOM 3448 C CG . GLU A 1 526 ? -30.027 -39.062 36.844 1.00 89.73 ? 499 GLU A CG 1 ATOM 3449 C CD . GLU A 1 526 ? -30.872 -40.094 37.568 1.00 96.73 ? 499 GLU A CD 1 ATOM 3450 O OE1 . GLU A 1 526 ? -32.007 -40.345 37.104 1.00 101.00 ? 499 GLU A OE1 1 ATOM 3451 O OE2 . GLU A 1 526 ? -30.417 -40.651 38.593 1.00 96.46 ? 499 GLU A OE2 1 ATOM 3452 N N . ASP A 1 527 ? -27.756 -36.287 38.831 1.00 83.92 ? 500 ASP A N 1 ATOM 3453 C CA . ASP A 1 527 ? -26.636 -35.391 38.577 1.00 78.45 ? 500 ASP A CA 1 ATOM 3454 C C . ASP A 1 527 ? -26.379 -34.376 39.694 1.00 72.83 ? 500 ASP A C 1 ATOM 3455 O O . ASP A 1 527 ? -25.250 -33.912 39.863 1.00 63.52 ? 500 ASP A O 1 ATOM 3456 C CB . ASP A 1 527 ? -26.922 -34.647 37.264 1.00 79.53 ? 500 ASP A CB 1 ATOM 3457 C CG . ASP A 1 527 ? -25.678 -34.299 36.505 1.00 85.64 ? 500 ASP A CG 1 ATOM 3458 O OD1 . ASP A 1 527 ? -24.580 -34.277 37.098 1.00 91.17 ? 500 ASP A OD1 1 ATOM 3459 O OD2 . ASP A 1 527 ? -25.802 -34.051 35.291 1.00 94.73 ? 500 ASP A OD2 1 ATOM 3460 N N . GLY A 1 528 ? -27.427 -34.021 40.438 1.00 66.87 ? 501 GLY A N 1 ATOM 3461 C CA . GLY A 1 528 ? -27.356 -32.907 41.385 1.00 66.02 ? 501 GLY A CA 1 ATOM 3462 C C . GLY A 1 528 ? -27.436 -31.538 40.706 1.00 65.23 ? 501 GLY A C 1 ATOM 3463 O O . GLY A 1 528 ? -27.431 -30.510 41.386 1.00 62.73 ? 501 GLY A O 1 ATOM 3464 N N . SER A 1 529 ? -27.530 -31.517 39.374 1.00 59.75 ? 502 SER A N 1 ATOM 3465 C CA . SER A 1 529 ? -27.532 -30.275 38.621 1.00 58.97 ? 502 SER A CA 1 ATOM 3466 C C . SER A 1 529 ? -28.966 -29.814 38.369 1.00 61.66 ? 502 SER A C 1 ATOM 3467 O O . SER A 1 529 ? -29.924 -30.589 38.514 1.00 60.00 ? 502 SER A O 1 ATOM 3468 C CB . SER A 1 529 ? -26.791 -30.436 37.296 1.00 58.77 ? 502 SER A CB 1 ATOM 3469 O OG . SER A 1 529 ? -27.484 -31.312 36.423 1.00 63.47 ? 502 SER A OG 1 ATOM 3470 N N . ILE A 1 530 ? -29.103 -28.548 37.984 1.00 53.69 ? 503 ILE A N 1 ATOM 3471 C CA . ILE A 1 530 ? -30.408 -27.970 37.711 1.00 50.90 ? 503 ILE A CA 1 ATOM 3472 C C . ILE A 1 530 ? -30.853 -28.355 36.320 1.00 49.72 ? 503 ILE A C 1 ATOM 3473 O O . ILE A 1 530 ? -30.072 -28.302 35.371 1.00 53.43 ? 503 ILE A O 1 ATOM 3474 C CB . ILE A 1 530 ? -30.392 -26.446 37.942 1.00 52.87 ? 503 ILE A CB 1 ATOM 3475 C CG1 . ILE A 1 530 ? -30.158 -26.223 39.438 1.00 52.51 ? 503 ILE A CG1 1 ATOM 3476 C CG2 . ILE A 1 530 ? -31.692 -25.793 37.475 1.00 52.00 ? 503 ILE A CG2 1 ATOM 3477 C CD1 . ILE A 1 530 ? -30.020 -24.796 39.870 1.00 57.18 ? 503 ILE A CD1 1 ATOM 3478 N N . VAL A 1 531 ? -32.103 -28.804 36.213 1.00 49.17 ? 504 VAL A N 1 ATOM 3479 C CA . VAL A 1 531 ? -32.650 -29.202 34.928 1.00 51.10 ? 504 VAL A CA 1 ATOM 3480 C C . VAL A 1 531 ? -33.877 -28.363 34.637 1.00 49.91 ? 504 VAL A C 1 ATOM 3481 O O . VAL A 1 531 ? -34.658 -28.019 35.529 1.00 53.14 ? 504 VAL A O 1 ATOM 3482 C CB . VAL A 1 531 ? -32.931 -30.728 34.826 1.00 55.03 ? 504 VAL A CB 1 ATOM 3483 C CG1 . VAL A 1 531 ? -31.736 -31.528 35.341 1.00 54.92 ? 504 VAL A CG1 1 ATOM 3484 C CG2 . VAL A 1 531 ? -34.187 -31.133 35.571 1.00 54.40 ? 504 VAL A CG2 1 ATOM 3485 N N . PHE A 1 532 ? -34.029 -28.047 33.364 1.00 48.86 ? 505 PHE A N 1 ATOM 3486 C CA . PHE A 1 532 ? -35.063 -27.163 32.904 1.00 50.18 ? 505 PHE A CA 1 ATOM 3487 C C . PHE A 1 532 ? -36.226 -27.981 32.337 1.00 50.58 ? 505 PHE A C 1 ATOM 3488 O O . PHE A 1 532 ? -36.243 -28.320 31.160 1.00 51.83 ? 505 PHE A O 1 ATOM 3489 C CB . PHE A 1 532 ? -34.476 -26.213 31.848 1.00 52.76 ? 505 PHE A CB 1 ATOM 3490 C CG . PHE A 1 532 ? -33.280 -25.414 32.329 1.00 50.34 ? 505 PHE A CG 1 ATOM 3491 C CD1 . PHE A 1 532 ? -33.343 -24.651 33.491 1.00 49.63 ? 505 PHE A CD1 1 ATOM 3492 C CD2 . PHE A 1 532 ? -32.096 -25.417 31.615 1.00 51.30 ? 505 PHE A CD2 1 ATOM 3493 C CE1 . PHE A 1 532 ? -32.241 -23.922 33.938 1.00 48.56 ? 505 PHE A CE1 1 ATOM 3494 C CE2 . PHE A 1 532 ? -30.992 -24.686 32.054 1.00 51.90 ? 505 PHE A CE2 1 ATOM 3495 C CZ . PHE A 1 532 ? -31.064 -23.939 33.217 1.00 46.84 ? 505 PHE A CZ 1 ATOM 3496 N N . LYS A 1 533 ? -37.212 -28.270 33.175 1.00 50.16 ? 506 LYS A N 1 ATOM 3497 C CA . LYS A 1 533 ? -38.353 -29.101 32.771 1.00 53.16 ? 506 LYS A CA 1 ATOM 3498 C C . LYS A 1 533 ? -39.393 -28.244 32.055 1.00 49.68 ? 506 LYS A C 1 ATOM 3499 O O . LYS A 1 533 ? -39.766 -27.180 32.569 1.00 48.01 ? 506 LYS A O 1 ATOM 3500 C CB . LYS A 1 533 ? -38.981 -29.761 34.019 1.00 59.10 ? 506 LYS A CB 1 ATOM 3501 C CG . LYS A 1 533 ? -39.574 -31.155 33.809 1.00 64.86 ? 506 LYS A CG 1 ATOM 3502 C CD . LYS A 1 533 ? -40.641 -31.165 32.721 1.00 72.62 ? 506 LYS A CD 1 ATOM 3503 C CE . LYS A 1 533 ? -41.747 -32.192 32.955 1.00 78.49 ? 506 LYS A CE 1 ATOM 3504 N NZ . LYS A 1 533 ? -41.292 -33.608 32.897 1.00 78.43 ? 506 LYS A NZ 1 ATOM 3505 N N . GLU A 1 534 ? -39.842 -28.674 30.873 1.00 45.93 ? 507 GLU A N 1 ATOM 3506 C CA . GLU A 1 534 ? -40.955 -27.980 30.203 1.00 50.48 ? 507 GLU A CA 1 ATOM 3507 C C . GLU A 1 534 ? -42.277 -28.287 30.898 1.00 51.23 ? 507 GLU A C 1 ATOM 3508 O O . GLU A 1 534 ? -42.646 -29.447 31.032 1.00 53.53 ? 507 GLU A O 1 ATOM 3509 C CB . GLU A 1 534 ? -41.107 -28.342 28.723 1.00 51.51 ? 507 GLU A CB 1 ATOM 3510 C CG . GLU A 1 534 ? -42.349 -27.665 28.133 1.00 56.39 ? 507 GLU A CG 1 ATOM 3511 C CD . GLU A 1 534 ? -42.517 -27.781 26.621 1.00 59.69 ? 507 GLU A CD 1 ATOM 3512 O OE1 . GLU A 1 534 ? -43.683 -27.758 26.153 1.00 58.63 ? 507 GLU A OE1 1 ATOM 3513 O OE2 . GLU A 1 534 ? -41.499 -27.879 25.901 1.00 64.18 ? 507 GLU A OE2 1 ATOM 3514 N N . VAL A 1 535 ? -43.000 -27.245 31.289 1.00 44.10 ? 508 VAL A N 1 ATOM 3515 C CA . VAL A 1 535 ? -44.268 -27.399 31.975 1.00 40.94 ? 508 VAL A CA 1 ATOM 3516 C C . VAL A 1 535 ? -45.400 -26.693 31.278 1.00 40.97 ? 508 VAL A C 1 ATOM 3517 O O . VAL A 1 535 ? -46.540 -26.687 31.754 1.00 45.11 ? 508 VAL A O 1 ATOM 3518 C CB . VAL A 1 535 ? -44.182 -26.910 33.412 1.00 40.00 ? 508 VAL A CB 1 ATOM 3519 C CG1 . VAL A 1 535 ? -43.119 -27.695 34.144 1.00 41.89 ? 508 VAL A CG1 1 ATOM 3520 C CG2 . VAL A 1 535 ? -43.861 -25.418 33.467 1.00 44.50 ? 508 VAL A CG2 1 ATOM 3521 N N . GLY A 1 536 ? -45.114 -26.121 30.125 1.00 39.54 ? 509 GLY A N 1 ATOM 3522 C CA . GLY A 1 536 ? -46.151 -25.387 29.438 1.00 41.37 ? 509 GLY A CA 1 ATOM 3523 C C . GLY A 1 536 ? -45.619 -24.720 28.207 1.00 37.96 ? 509 GLY A C 1 ATOM 3524 O O . GLY A 1 536 ? -44.478 -24.937 27.816 1.00 34.79 ? 509 GLY A O 1 ATOM 3525 N N . TYR A 1 537 ? -46.473 -23.950 27.562 1.00 37.46 ? 510 TYR A N 1 ATOM 3526 C CA . TYR A 1 537 ? -46.037 -23.201 26.408 1.00 42.09 ? 510 TYR A CA 1 ATOM 3527 C C . TYR A 1 537 ? -46.919 -21.993 26.276 1.00 40.50 ? 510 TYR A C 1 ATOM 3528 O O . TYR A 1 537 ? -47.993 -21.900 26.904 1.00 40.82 ? 510 TYR A O 1 ATOM 3529 C CB . TYR A 1 537 ? -46.042 -24.047 25.116 1.00 47.15 ? 510 TYR A CB 1 ATOM 3530 C CG . TYR A 1 537 ? -47.413 -24.580 24.708 1.00 54.22 ? 510 TYR A CG 1 ATOM 3531 C CD1 . TYR A 1 537 ? -48.341 -23.764 24.040 1.00 61.22 ? 510 TYR A CD1 1 ATOM 3532 C CD2 . TYR A 1 537 ? -47.797 -25.907 24.980 1.00 62.33 ? 510 TYR A CD2 1 ATOM 3533 C CE1 . TYR A 1 537 ? -49.601 -24.243 23.674 1.00 62.49 ? 510 TYR A CE1 1 ATOM 3534 C CE2 . TYR A 1 537 ? -49.060 -26.394 24.604 1.00 58.26 ? 510 TYR A CE2 1 ATOM 3535 C CZ . TYR A 1 537 ? -49.948 -25.557 23.952 1.00 58.93 ? 510 TYR A CZ 1 ATOM 3536 O OH . TYR A 1 537 ? -51.186 -26.007 23.580 1.00 67.29 ? 510 TYR A OH 1 ATOM 3537 N N . TYR A 1 538 ? -46.439 -21.064 25.471 1.00 38.58 ? 511 TYR A N 1 ATOM 3538 C CA . TYR A 1 538 ? -47.151 -19.855 25.202 1.00 38.87 ? 511 TYR A CA 1 ATOM 3539 C C . TYR A 1 538 ? -47.213 -19.697 23.691 1.00 39.62 ? 511 TYR A C 1 ATOM 3540 O O . TYR A 1 538 ? -46.173 -19.540 23.019 1.00 40.25 ? 511 TYR A O 1 ATOM 3541 C CB . TYR A 1 538 ? -46.468 -18.669 25.883 1.00 35.83 ? 511 TYR A CB 1 ATOM 3542 C CG . TYR A 1 538 ? -47.358 -17.458 26.003 1.00 35.73 ? 511 TYR A CG 1 ATOM 3543 C CD1 . TYR A 1 538 ? -48.356 -17.412 26.971 1.00 36.22 ? 511 TYR A CD1 1 ATOM 3544 C CD2 . TYR A 1 538 ? -47.198 -16.361 25.172 1.00 35.12 ? 511 TYR A CD2 1 ATOM 3545 C CE1 . TYR A 1 538 ? -49.180 -16.316 27.103 1.00 36.12 ? 511 TYR A CE1 1 ATOM 3546 C CE2 . TYR A 1 538 ? -48.026 -15.259 25.297 1.00 34.34 ? 511 TYR A CE2 1 ATOM 3547 C CZ . TYR A 1 538 ? -49.012 -15.253 26.272 1.00 34.86 ? 511 TYR A CZ 1 ATOM 3548 O OH . TYR A 1 538 ? -49.848 -14.201 26.436 1.00 32.92 ? 511 TYR A OH 1 ATOM 3549 N N . ASN A 1 539 ? -48.433 -19.777 23.166 1.00 37.42 ? 512 ASN A N 1 ATOM 3550 C CA . ASN A 1 539 ? -48.672 -19.742 21.727 1.00 40.76 ? 512 ASN A CA 1 ATOM 3551 C C . ASN A 1 539 ? -49.147 -18.369 21.357 1.00 38.41 ? 512 ASN A C 1 ATOM 3552 O O . ASN A 1 539 ? -50.306 -18.028 21.578 1.00 38.51 ? 512 ASN A O 1 ATOM 3553 C CB . ASN A 1 539 ? -49.728 -20.792 21.335 1.00 42.30 ? 512 ASN A CB 1 ATOM 3554 C CG . ASN A 1 539 ? -50.263 -20.612 19.916 1.00 46.64 ? 512 ASN A CG 1 ATOM 3555 O OD1 . ASN A 1 539 ? -49.738 -19.845 19.110 1.00 50.36 ? 512 ASN A OD1 1 ATOM 3556 N ND2 . ASN A 1 539 ? -51.321 -21.346 19.602 1.00 49.81 ? 512 ASN A ND2 1 ATOM 3557 N N . VAL A 1 540 ? -48.256 -17.586 20.756 1.00 38.37 ? 513 VAL A N 1 ATOM 3558 C CA . VAL A 1 540 ? -48.551 -16.180 20.449 1.00 38.68 ? 513 VAL A CA 1 ATOM 3559 C C . VAL A 1 540 ? -49.522 -16.007 19.288 1.00 44.35 ? 513 VAL A C 1 ATOM 3560 O O . VAL A 1 540 ? -49.965 -14.877 19.047 1.00 44.91 ? 513 VAL A O 1 ATOM 3561 C CB . VAL A 1 540 ? -47.266 -15.338 20.202 1.00 39.37 ? 513 VAL A CB 1 ATOM 3562 C CG1 . VAL A 1 540 ? -46.327 -15.427 21.392 1.00 38.49 ? 513 VAL A CG1 1 ATOM 3563 C CG2 . VAL A 1 540 ? -46.523 -15.755 18.929 1.00 39.47 ? 513 VAL A CG2 1 ATOM 3564 N N . TYR A 1 541 ? -49.894 -17.096 18.596 1.00 45.87 ? 514 TYR A N 1 ATOM 3565 C CA . TYR A 1 541 ? -50.866 -16.998 17.488 1.00 51.48 ? 514 TYR A CA 1 ATOM 3566 C C . TYR A 1 541 ? -52.323 -17.141 17.905 1.00 51.25 ? 514 TYR A C 1 ATOM 3567 O O . TYR A 1 541 ? -53.209 -16.809 17.135 1.00 52.79 ? 514 TYR A O 1 ATOM 3568 C CB . TYR A 1 541 ? -50.571 -18.003 16.374 1.00 56.08 ? 514 TYR A CB 1 ATOM 3569 C CG . TYR A 1 541 ? -49.219 -17.773 15.760 1.00 56.28 ? 514 TYR A CG 1 ATOM 3570 C CD1 . TYR A 1 541 ? -48.087 -18.321 16.340 1.00 57.09 ? 514 TYR A CD1 1 ATOM 3571 C CD2 . TYR A 1 541 ? -49.065 -16.965 14.636 1.00 59.47 ? 514 TYR A CD2 1 ATOM 3572 C CE1 . TYR A 1 541 ? -46.835 -18.097 15.815 1.00 57.04 ? 514 TYR A CE1 1 ATOM 3573 C CE2 . TYR A 1 541 ? -47.809 -16.744 14.089 1.00 59.30 ? 514 TYR A CE2 1 ATOM 3574 C CZ . TYR A 1 541 ? -46.699 -17.317 14.690 1.00 58.62 ? 514 TYR A CZ 1 ATOM 3575 O OH . TYR A 1 541 ? -45.434 -17.122 14.184 1.00 62.17 ? 514 TYR A OH 1 ATOM 3576 N N . ALA A 1 542 ? -52.565 -17.593 19.128 1.00 49.72 ? 515 ALA A N 1 ATOM 3577 C CA . ALA A 1 542 ? -53.926 -17.827 19.601 1.00 50.69 ? 515 ALA A CA 1 ATOM 3578 C C . ALA A 1 542 ? -54.522 -16.495 20.033 1.00 53.62 ? 515 ALA A C 1 ATOM 3579 O O . ALA A 1 542 ? -53.801 -15.505 20.154 1.00 52.85 ? 515 ALA A O 1 ATOM 3580 C CB . ALA A 1 542 ? -53.920 -18.818 20.752 1.00 48.67 ? 515 ALA A CB 1 ATOM 3581 N N . LYS A 1 543 ? -55.835 -16.467 20.238 1.00 56.22 ? 516 LYS A N 1 ATOM 3582 C CA . LYS A 1 543 ? -56.525 -15.238 20.624 1.00 60.02 ? 516 LYS A CA 1 ATOM 3583 C C . LYS A 1 543 ? -56.164 -14.875 22.065 1.00 59.36 ? 516 LYS A C 1 ATOM 3584 O O . LYS A 1 543 ? -55.820 -15.747 22.858 1.00 58.67 ? 516 LYS A O 1 ATOM 3585 C CB . LYS A 1 543 ? -58.047 -15.392 20.470 1.00 60.61 ? 516 LYS A CB 1 ATOM 3586 N N . LYS A 1 544 ? -56.257 -13.589 22.394 1.00 60.12 ? 517 LYS A N 1 ATOM 3587 C CA . LYS A 1 544 ? -56.013 -13.102 23.755 1.00 61.83 ? 517 LYS A CA 1 ATOM 3588 C C . LYS A 1 544 ? -56.660 -14.027 24.780 1.00 60.43 ? 517 LYS A C 1 ATOM 3589 O O . LYS A 1 544 ? -57.789 -14.456 24.584 1.00 61.64 ? 517 LYS A O 1 ATOM 3590 C CB . LYS A 1 544 ? -56.657 -11.738 23.964 1.00 65.20 ? 517 LYS A CB 1 ATOM 3591 C CG . LYS A 1 544 ? -55.903 -10.522 23.464 1.00 72.66 ? 517 LYS A CG 1 ATOM 3592 C CD . LYS A 1 544 ? -56.725 -9.253 23.716 1.00 78.78 ? 517 LYS A CD 1 ATOM 3593 C CE . LYS A 1 544 ? -56.456 -8.159 22.692 1.00 80.68 ? 517 LYS A CE 1 ATOM 3594 N NZ . LYS A 1 544 ? -55.155 -7.477 22.919 1.00 83.22 ? 517 LYS A NZ 1 ATOM 3595 N N . GLY A 1 545 ? -55.967 -14.294 25.882 1.00 59.66 ? 518 GLY A N 1 ATOM 3596 C CA . GLY A 1 545 ? -56.508 -15.120 26.962 1.00 56.88 ? 518 GLY A CA 1 ATOM 3597 C C . GLY A 1 545 ? -56.583 -16.608 26.664 1.00 55.57 ? 518 GLY A C 1 ATOM 3598 O O . GLY A 1 545 ? -57.067 -17.373 27.491 1.00 53.99 ? 518 GLY A O 1 ATOM 3599 N N . GLU A 1 546 ? -56.115 -17.023 25.487 1.00 54.92 ? 519 GLU A N 1 ATOM 3600 C CA . GLU A 1 546 ? -56.072 -18.433 25.120 1.00 53.36 ? 519 GLU A CA 1 ATOM 3601 C C . GLU A 1 546 ? -54.684 -18.844 24.632 1.00 50.93 ? 519 GLU A C 1 ATOM 3602 O O . GLU A 1 546 ? -54.527 -19.853 23.956 1.00 50.59 ? 519 GLU A O 1 ATOM 3603 C CB . GLU A 1 546 ? -57.125 -18.700 24.050 1.00 58.74 ? 519 GLU A CB 1 ATOM 3604 C CG . GLU A 1 546 ? -58.543 -18.657 24.604 1.00 62.43 ? 519 GLU A CG 1 ATOM 3605 C CD . GLU A 1 546 ? -59.596 -18.638 23.523 1.00 67.40 ? 519 GLU A CD 1 ATOM 3606 O OE1 . GLU A 1 546 ? -59.285 -19.047 22.386 1.00 73.00 ? 519 GLU A OE1 1 ATOM 3607 O OE2 . GLU A 1 546 ? -60.736 -18.212 23.808 1.00 69.92 ? 519 GLU A OE2 1 ATOM 3608 N N . ARG A 1 547 ? -53.673 -18.075 25.018 1.00 46.77 ? 520 ARG A N 1 ATOM 3609 C CA . ARG A 1 547 ? -52.304 -18.289 24.554 1.00 42.61 ? 520 ARG A CA 1 ATOM 3610 C C . ARG A 1 547 ? -51.485 -19.115 25.515 1.00 38.25 ? 520 ARG A C 1 ATOM 3611 O O . ARG A 1 547 ? -50.550 -19.791 25.112 1.00 33.32 ? 520 ARG A O 1 ATOM 3612 C CB . ARG A 1 547 ? -51.632 -16.940 24.325 1.00 43.73 ? 520 ARG A CB 1 ATOM 3613 C CG . ARG A 1 547 ? -52.330 -16.102 23.280 1.00 43.34 ? 520 ARG A CG 1 ATOM 3614 C CD . ARG A 1 547 ? -51.658 -14.761 23.101 1.00 43.19 ? 520 ARG A CD 1 ATOM 3615 N NE . ARG A 1 547 ? -52.428 -13.948 22.176 1.00 45.79 ? 520 ARG A NE 1 ATOM 3616 C CZ . ARG A 1 547 ? -52.513 -12.624 22.206 1.00 48.29 ? 520 ARG A CZ 1 ATOM 3617 N NH1 . ARG A 1 547 ? -51.860 -11.909 23.126 1.00 53.07 ? 520 ARG A NH1 1 ATOM 3618 N NH2 . ARG A 1 547 ? -53.270 -12.010 21.314 1.00 47.88 ? 520 ARG A NH2 1 ATOM 3619 N N . LEU A 1 548 ? -51.810 -19.022 26.793 1.00 35.88 ? 521 LEU A N 1 ATOM 3620 C CA . LEU A 1 548 ? -51.150 -19.809 27.809 1.00 38.24 ? 521 LEU A CA 1 ATOM 3621 C C . LEU A 1 548 ? -51.667 -21.242 27.931 1.00 42.17 ? 521 LEU A C 1 ATOM 3622 O O . LEU A 1 548 ? -52.884 -21.477 28.044 1.00 43.39 ? 521 LEU A O 1 ATOM 3623 C CB . LEU A 1 548 ? -51.340 -19.135 29.164 1.00 35.99 ? 521 LEU A CB 1 ATOM 3624 C CG . LEU A 1 548 ? -50.608 -19.734 30.372 1.00 35.20 ? 521 LEU A CG 1 ATOM 3625 C CD1 . LEU A 1 548 ? -49.113 -19.725 30.177 1.00 35.54 ? 521 LEU A CD1 1 ATOM 3626 C CD2 . LEU A 1 548 ? -50.994 -18.916 31.596 1.00 35.83 ? 521 LEU A CD2 1 ATOM 3627 N N . PHE A 1 549 ? -50.734 -22.187 27.941 1.00 40.79 ? 522 PHE A N 1 ATOM 3628 C CA . PHE A 1 549 ? -51.004 -23.516 28.439 1.00 41.93 ? 522 PHE A CA 1 ATOM 3629 C C . PHE A 1 549 ? -49.982 -23.912 29.481 1.00 40.71 ? 522 PHE A C 1 ATOM 3630 O O . PHE A 1 549 ? -48.786 -23.876 29.209 1.00 42.29 ? 522 PHE A O 1 ATOM 3631 C CB . PHE A 1 549 ? -50.955 -24.538 27.315 1.00 44.71 ? 522 PHE A CB 1 ATOM 3632 C CG . PHE A 1 549 ? -50.932 -25.952 27.813 1.00 49.09 ? 522 PHE A CG 1 ATOM 3633 C CD1 . PHE A 1 549 ? -52.112 -26.569 28.238 1.00 50.73 ? 522 PHE A CD1 1 ATOM 3634 C CD2 . PHE A 1 549 ? -49.732 -26.645 27.928 1.00 50.00 ? 522 PHE A CD2 1 ATOM 3635 C CE1 . PHE A 1 549 ? -52.093 -27.860 28.733 1.00 50.52 ? 522 PHE A CE1 1 ATOM 3636 C CE2 . PHE A 1 549 ? -49.708 -27.939 28.425 1.00 54.48 ? 522 PHE A CE2 1 ATOM 3637 C CZ . PHE A 1 549 ? -50.893 -28.546 28.827 1.00 52.66 ? 522 PHE A CZ 1 ATOM 3638 N N . ILE A 1 550 ? -50.463 -24.376 30.635 1.00 42.22 ? 523 ILE A N 1 ATOM 3639 C CA . ILE A 1 550 ? -49.607 -24.900 31.689 1.00 46.10 ? 523 ILE A CA 1 ATOM 3640 C C . ILE A 1 550 ? -50.093 -26.245 32.170 1.00 47.65 ? 523 ILE A C 1 ATOM 3641 O O . ILE A 1 550 ? -51.285 -26.443 32.368 1.00 49.23 ? 523 ILE A O 1 ATOM 3642 C CB . ILE A 1 550 ? -49.596 -23.970 32.900 1.00 53.78 ? 523 ILE A CB 1 ATOM 3643 C CG1 . ILE A 1 550 ? -48.702 -22.784 32.593 1.00 61.16 ? 523 ILE A CG1 1 ATOM 3644 C CG2 . ILE A 1 550 ? -49.058 -24.677 34.144 1.00 56.21 ? 523 ILE A CG2 1 ATOM 3645 C CD1 . ILE A 1 550 ? -48.966 -21.605 33.478 1.00 65.28 ? 523 ILE A CD1 1 ATOM 3646 N N . ASN A 1 551 ? -49.158 -27.174 32.338 1.00 48.38 ? 524 ASN A N 1 ATOM 3647 C CA . ASN A 1 551 ? -49.442 -28.432 32.981 1.00 47.19 ? 524 ASN A CA 1 ATOM 3648 C C . ASN A 1 551 ? -49.057 -28.343 34.455 1.00 43.06 ? 524 ASN A C 1 ATOM 3649 O O . ASN A 1 551 ? -47.929 -28.654 34.827 1.00 39.65 ? 524 ASN A O 1 ATOM 3650 C CB . ASN A 1 551 ? -48.683 -29.558 32.281 1.00 50.66 ? 524 ASN A CB 1 ATOM 3651 C CG . ASN A 1 551 ? -49.230 -30.924 32.641 1.00 55.82 ? 524 ASN A CG 1 ATOM 3652 O OD1 . ASN A 1 551 ? -49.679 -31.147 33.773 1.00 55.12 ? 524 ASN A OD1 1 ATOM 3653 N ND2 . ASN A 1 551 ? -49.220 -31.840 31.681 1.00 56.13 ? 524 ASN A ND2 1 ATOM 3654 N N . GLU A 1 552 ? -50.026 -27.955 35.283 1.00 45.35 ? 525 GLU A N 1 ATOM 3655 C CA . GLU A 1 552 ? -49.824 -27.767 36.743 1.00 49.10 ? 525 GLU A CA 1 ATOM 3656 C C . GLU A 1 552 ? -49.207 -28.985 37.434 1.00 48.28 ? 525 GLU A C 1 ATOM 3657 O O . GLU A 1 552 ? -48.349 -28.844 38.307 1.00 46.48 ? 525 GLU A O 1 ATOM 3658 C CB . GLU A 1 552 ? -51.159 -27.472 37.456 1.00 47.85 ? 525 GLU A CB 1 ATOM 3659 C CG . GLU A 1 552 ? -52.094 -26.465 36.778 1.00 49.85 ? 525 GLU A CG 1 ATOM 3660 C CD . GLU A 1 552 ? -53.368 -26.149 37.562 1.00 50.72 ? 525 GLU A CD 1 ATOM 3661 O OE1 . GLU A 1 552 ? -53.430 -26.432 38.777 1.00 49.12 ? 525 GLU A OE1 1 ATOM 3662 O OE2 . GLU A 1 552 ? -54.309 -25.578 36.959 1.00 51.68 ? 525 GLU A OE2 1 ATOM 3663 N N . GLU A 1 553 ? -49.621 -30.179 37.002 1.00 52.27 ? 526 GLU A N 1 ATOM 3664 C CA . GLU A 1 553 ? -49.106 -31.446 37.551 1.00 54.06 ? 526 GLU A CA 1 ATOM 3665 C C . GLU A 1 553 ? -47.577 -31.601 37.433 1.00 54.70 ? 526 GLU A C 1 ATOM 3666 O O . GLU A 1 553 ? -46.952 -32.246 38.273 1.00 52.49 ? 526 GLU A O 1 ATOM 3667 C CB . GLU A 1 553 ? -49.816 -32.641 36.894 1.00 51.35 ? 526 GLU A CB 1 ATOM 3668 N N . LYS A 1 554 ? -46.974 -30.971 36.426 1.00 53.21 ? 527 LYS A N 1 ATOM 3669 C CA . LYS A 1 554 ? -45.519 -31.057 36.239 1.00 54.48 ? 527 LYS A CA 1 ATOM 3670 C C . LYS A 1 554 ? -44.683 -30.054 37.029 1.00 51.35 ? 527 LYS A C 1 ATOM 3671 O O . LYS A 1 554 ? -43.446 -30.155 37.074 1.00 49.05 ? 527 LYS A O 1 ATOM 3672 C CB . LYS A 1 554 ? -45.196 -30.896 34.773 1.00 58.34 ? 527 LYS A CB 1 ATOM 3673 C CG . LYS A 1 554 ? -45.775 -32.010 33.934 1.00 61.78 ? 527 LYS A CG 1 ATOM 3674 C CD . LYS A 1 554 ? -45.507 -31.770 32.467 1.00 63.89 ? 527 LYS A CD 1 ATOM 3675 C CE . LYS A 1 554 ? -45.461 -33.069 31.692 1.00 63.95 ? 527 LYS A CE 1 ATOM 3676 N NZ . LYS A 1 554 ? -45.648 -32.789 30.245 1.00 64.45 ? 527 LYS A NZ 1 ATOM 3677 N N . ILE A 1 555 ? -45.337 -29.102 37.686 1.00 49.01 ? 528 ILE A N 1 ATOM 3678 C CA . ILE A 1 555 ? -44.586 -28.067 38.390 1.00 46.31 ? 528 ILE A CA 1 ATOM 3679 C C . ILE A 1 555 ? -44.163 -28.623 39.721 1.00 45.29 ? 528 ILE A C 1 ATOM 3680 O O . ILE A 1 555 ? -44.960 -29.254 40.407 1.00 41.71 ? 528 ILE A O 1 ATOM 3681 C CB . ILE A 1 555 ? -45.429 -26.790 38.580 1.00 46.92 ? 528 ILE A CB 1 ATOM 3682 C CG1 . ILE A 1 555 ? -45.658 -26.124 37.224 1.00 45.72 ? 528 ILE A CG1 1 ATOM 3683 C CG2 . ILE A 1 555 ? -44.740 -25.805 39.519 1.00 47.21 ? 528 ILE A CG2 1 ATOM 3684 C CD1 . ILE A 1 555 ? -46.821 -25.152 37.238 1.00 45.90 ? 528 ILE A CD1 1 ATOM 3685 N N . LEU A 1 556 ? -42.890 -28.448 40.053 1.00 45.63 ? 529 LEU A N 1 ATOM 3686 C CA . LEU A 1 556 ? -42.423 -28.647 41.394 1.00 46.21 ? 529 LEU A CA 1 ATOM 3687 C C . LEU A 1 556 ? -42.216 -27.295 42.044 1.00 49.27 ? 529 LEU A C 1 ATOM 3688 O O . LEU A 1 556 ? -41.390 -26.484 41.592 1.00 52.74 ? 529 LEU A O 1 ATOM 3689 C CB . LEU A 1 556 ? -41.160 -29.496 41.372 1.00 50.69 ? 529 LEU A CB 1 ATOM 3690 C CG . LEU A 1 556 ? -41.412 -30.897 40.771 1.00 54.32 ? 529 LEU A CG 1 ATOM 3691 C CD1 . LEU A 1 556 ? -40.110 -31.681 40.612 1.00 52.50 ? 529 LEU A CD1 1 ATOM 3692 C CD2 . LEU A 1 556 ? -42.425 -31.689 41.603 1.00 52.91 ? 529 LEU A CD2 1 ATOM 3693 N N . TRP A 1 557 ? -42.984 -27.047 43.105 1.00 47.05 ? 530 TRP A N 1 ATOM 3694 C CA . TRP A 1 557 ? -42.936 -25.774 43.800 1.00 46.54 ? 530 TRP A CA 1 ATOM 3695 C C . TRP A 1 557 ? -41.710 -25.754 44.672 1.00 46.75 ? 530 TRP A C 1 ATOM 3696 O O . TRP A 1 557 ? -41.349 -26.761 45.288 1.00 49.67 ? 530 TRP A O 1 ATOM 3697 C CB . TRP A 1 557 ? -44.201 -25.548 44.600 1.00 46.05 ? 530 TRP A CB 1 ATOM 3698 C CG . TRP A 1 557 ? -45.354 -25.535 43.697 1.00 47.14 ? 530 TRP A CG 1 ATOM 3699 C CD1 . TRP A 1 557 ? -46.218 -26.546 43.457 1.00 46.52 ? 530 TRP A CD1 1 ATOM 3700 C CD2 . TRP A 1 557 ? -45.729 -24.464 42.825 1.00 50.02 ? 530 TRP A CD2 1 ATOM 3701 N NE1 . TRP A 1 557 ? -47.134 -26.173 42.499 1.00 47.07 ? 530 TRP A NE1 1 ATOM 3702 C CE2 . TRP A 1 557 ? -46.860 -24.895 42.102 1.00 45.90 ? 530 TRP A CE2 1 ATOM 3703 C CE3 . TRP A 1 557 ? -45.216 -23.177 42.586 1.00 47.15 ? 530 TRP A CE3 1 ATOM 3704 C CZ2 . TRP A 1 557 ? -47.494 -24.090 41.164 1.00 46.05 ? 530 TRP A CZ2 1 ATOM 3705 C CZ3 . TRP A 1 557 ? -45.838 -22.383 41.646 1.00 45.35 ? 530 TRP A CZ3 1 ATOM 3706 C CH2 . TRP A 1 557 ? -46.971 -22.837 40.951 1.00 47.18 ? 530 TRP A CH2 1 ATOM 3707 N N . SER A 1 558 ? -41.048 -24.611 44.682 1.00 43.33 ? 531 SER A N 1 ATOM 3708 C CA . SER A 1 558 ? -39.736 -24.466 45.296 1.00 45.15 ? 531 SER A CA 1 ATOM 3709 C C . SER A 1 558 ? -38.755 -25.497 44.719 1.00 45.32 ? 531 SER A C 1 ATOM 3710 O O . SER A 1 558 ? -37.678 -25.699 45.278 1.00 43.87 ? 531 SER A O 1 ATOM 3711 C CB . SER A 1 558 ? -39.810 -24.574 46.818 1.00 45.08 ? 531 SER A CB 1 ATOM 3712 O OG . SER A 1 558 ? -40.639 -23.549 47.319 1.00 47.96 ? 531 SER A OG 1 ATOM 3713 N N . GLY A 1 559 ? -39.121 -26.103 43.585 1.00 43.76 ? 532 GLY A N 1 ATOM 3714 C CA . GLY A 1 559 ? -38.249 -27.019 42.858 1.00 50.50 ? 532 GLY A CA 1 ATOM 3715 C C . GLY A 1 559 ? -38.460 -28.505 43.108 1.00 54.75 ? 532 GLY A C 1 ATOM 3716 O O . GLY A 1 559 ? -37.970 -29.322 42.323 1.00 56.54 ? 532 GLY A O 1 ATOM 3717 N N . PHE A 1 560 ? -39.200 -28.846 44.172 1.00 56.09 ? 533 PHE A N 1 ATOM 3718 C CA . PHE A 1 560 ? -39.356 -30.243 44.639 1.00 58.40 ? 533 PHE A CA 1 ATOM 3719 C C . PHE A 1 560 ? -40.779 -30.718 45.028 1.00 58.60 ? 533 PHE A C 1 ATOM 3720 O O . PHE A 1 560 ? -41.008 -31.930 45.099 1.00 56.22 ? 533 PHE A O 1 ATOM 3721 C CB . PHE A 1 560 ? -38.419 -30.490 45.836 1.00 56.41 ? 533 PHE A CB 1 ATOM 3722 C CG . PHE A 1 560 ? -38.689 -29.593 47.018 1.00 59.45 ? 533 PHE A CG 1 ATOM 3723 C CD1 . PHE A 1 560 ? -39.575 -29.987 48.024 1.00 59.79 ? 533 PHE A CD1 1 ATOM 3724 C CD2 . PHE A 1 560 ? -38.050 -28.352 47.133 1.00 58.09 ? 533 PHE A CD2 1 ATOM 3725 C CE1 . PHE A 1 560 ? -39.825 -29.157 49.115 1.00 63.07 ? 533 PHE A CE1 1 ATOM 3726 C CE2 . PHE A 1 560 ? -38.296 -27.517 48.220 1.00 60.68 ? 533 PHE A CE2 1 ATOM 3727 C CZ . PHE A 1 560 ? -39.184 -27.918 49.214 1.00 63.58 ? 533 PHE A CZ 1 ATOM 3728 N N . SER A 1 561 ? -41.718 -29.798 45.288 1.00 56.15 ? 534 SER A N 1 ATOM 3729 C CA . SER A 1 561 ? -43.011 -30.154 45.900 1.00 51.01 ? 534 SER A CA 1 ATOM 3730 C C . SER A 1 561 ? -44.160 -30.216 44.897 1.00 51.26 ? 534 SER A C 1 ATOM 3731 O O . SER A 1 561 ? -44.420 -29.245 44.186 1.00 49.21 ? 534 SER A O 1 ATOM 3732 C CB . SER A 1 561 ? -43.355 -29.153 46.999 1.00 52.48 ? 534 SER A CB 1 ATOM 3733 O OG . SER A 1 561 ? -44.572 -29.488 47.640 1.00 49.09 ? 534 SER A OG 1 ATOM 3734 N N . ARG A 1 562 ? -44.829 -31.372 44.846 1.00 52.60 ? 535 ARG A N 1 ATOM 3735 C CA . ARG A 1 562 ? -46.083 -31.554 44.103 1.00 54.18 ? 535 ARG A CA 1 ATOM 3736 C C . ARG A 1 562 ? -47.316 -31.091 44.895 1.00 55.44 ? 535 ARG A C 1 ATOM 3737 O O . ARG A 1 562 ? -48.392 -30.910 44.323 1.00 58.49 ? 535 ARG A O 1 ATOM 3738 C CB . ARG A 1 562 ? -46.265 -33.017 43.694 1.00 55.40 ? 535 ARG A CB 1 ATOM 3739 C CG . ARG A 1 562 ? -45.594 -33.395 42.382 1.00 60.30 ? 535 ARG A CG 1 ATOM 3740 C CD . ARG A 1 562 ? -46.451 -33.053 41.162 1.00 63.49 ? 535 ARG A CD 1 ATOM 3741 N NE . ARG A 1 562 ? -46.668 -31.610 41.025 1.00 70.61 ? 535 ARG A NE 1 ATOM 3742 C CZ . ARG A 1 562 ? -47.850 -30.977 41.046 1.00 70.61 ? 535 ARG A CZ 1 ATOM 3743 N NH1 . ARG A 1 562 ? -49.000 -31.639 41.164 1.00 69.23 ? 535 ARG A NH1 1 ATOM 3744 N NH2 . ARG A 1 562 ? -47.879 -29.651 40.923 1.00 72.18 ? 535 ARG A NH2 1 ATOM 3745 N N . GLU A 1 563 ? -47.154 -30.900 46.201 1.00 56.28 ? 536 GLU A N 1 ATOM 3746 C CA . GLU A 1 563 ? -48.229 -30.422 47.069 1.00 57.29 ? 536 GLU A CA 1 ATOM 3747 C C . GLU A 1 563 ? -48.252 -28.894 47.117 1.00 55.68 ? 536 GLU A C 1 ATOM 3748 O O . GLU A 1 563 ? -47.231 -28.281 47.411 1.00 53.20 ? 536 GLU A O 1 ATOM 3749 C CB . GLU A 1 563 ? -48.030 -30.970 48.482 1.00 59.65 ? 536 GLU A CB 1 ATOM 3750 C CG . GLU A 1 563 ? -48.456 -32.428 48.633 1.00 63.58 ? 536 GLU A CG 1 ATOM 3751 C CD . GLU A 1 563 ? -47.546 -33.390 47.905 1.00 64.41 ? 536 GLU A CD 1 ATOM 3752 O OE1 . GLU A 1 563 ? -46.346 -33.417 48.266 1.00 60.30 ? 536 GLU A OE1 1 ATOM 3753 O OE2 . GLU A 1 563 ? -48.032 -34.103 46.988 1.00 61.08 ? 536 GLU A OE2 1 ATOM 3754 N N . VAL A 1 564 ? -49.414 -28.292 46.839 1.00 55.13 ? 537 VAL A N 1 ATOM 3755 C CA . VAL A 1 564 ? -49.560 -26.825 46.804 1.00 54.78 ? 537 VAL A CA 1 ATOM 3756 C C . VAL A 1 564 ? -50.768 -26.372 47.622 1.00 50.77 ? 537 VAL A C 1 ATOM 3757 O O . VAL A 1 564 ? -51.865 -26.893 47.417 1.00 47.94 ? 537 VAL A O 1 ATOM 3758 C CB . VAL A 1 564 ? -49.797 -26.247 45.380 1.00 56.20 ? 537 VAL A CB 1 ATOM 3759 C CG1 . VAL A 1 564 ? -48.930 -25.009 45.181 1.00 57.11 ? 537 VAL A CG1 1 ATOM 3760 C CG2 . VAL A 1 564 ? -49.564 -27.281 44.286 1.00 59.43 ? 537 VAL A CG2 1 ATOM 3761 N N . PRO A 1 565 ? -50.574 -25.429 48.567 1.00 48.99 ? 538 PRO A N 1 ATOM 3762 C CA . PRO A 1 565 ? -49.296 -24.960 49.116 1.00 49.72 ? 538 PRO A CA 1 ATOM 3763 C C . PRO A 1 565 ? -48.842 -25.916 50.222 1.00 51.54 ? 538 PRO A C 1 ATOM 3764 O O . PRO A 1 565 ? -49.541 -26.898 50.496 1.00 50.33 ? 538 PRO A O 1 ATOM 3765 C CB . PRO A 1 565 ? -49.627 -23.568 49.648 1.00 48.55 ? 538 PRO A CB 1 ATOM 3766 C CG . PRO A 1 565 ? -51.086 -23.609 49.961 1.00 49.17 ? 538 PRO A CG 1 ATOM 3767 C CD . PRO A 1 565 ? -51.716 -24.746 49.198 1.00 48.65 ? 538 PRO A CD 1 ATOM 3768 N N . PHE A 1 566 ? -47.684 -25.661 50.826 1.00 55.58 ? 539 PHE A N 1 ATOM 3769 C CA . PHE A 1 566 ? -47.103 -26.597 51.813 1.00 60.86 ? 539 PHE A CA 1 ATOM 3770 C C . PHE A 1 566 ? -46.393 -25.883 52.977 1.00 57.93 ? 539 PHE A C 1 ATOM 3771 O O . PHE A 1 566 ? -46.004 -24.721 52.851 1.00 53.27 ? 539 PHE A O 1 ATOM 3772 C CB . PHE A 1 566 ? -46.154 -27.604 51.118 1.00 62.90 ? 539 PHE A CB 1 ATOM 3773 C CG . PHE A 1 566 ? -44.971 -26.967 50.425 1.00 64.07 ? 539 PHE A CG 1 ATOM 3774 C CD1 . PHE A 1 566 ? -43.784 -26.712 51.123 1.00 65.76 ? 539 PHE A CD1 1 ATOM 3775 C CD2 . PHE A 1 566 ? -45.034 -26.622 49.073 1.00 64.54 ? 539 PHE A CD2 1 ATOM 3776 C CE1 . PHE A 1 566 ? -42.689 -26.124 50.488 1.00 63.88 ? 539 PHE A CE1 1 ATOM 3777 C CE2 . PHE A 1 566 ? -43.945 -26.032 48.437 1.00 66.83 ? 539 PHE A CE2 1 ATOM 3778 C CZ . PHE A 1 566 ? -42.770 -25.786 49.145 1.00 63.33 ? 539 PHE A CZ 1 ATOM 3779 N N . GLY B 1 48 ? -17.048 18.260 8.261 1.00 76.05 ? 21 GLY B N 1 ATOM 3780 C CA . GLY B 1 48 ? -18.393 17.880 8.815 1.00 76.76 ? 21 GLY B CA 1 ATOM 3781 C C . GLY B 1 48 ? -19.573 18.484 8.058 1.00 77.12 ? 21 GLY B C 1 ATOM 3782 O O . GLY B 1 48 ? -19.458 18.736 6.860 1.00 81.61 ? 21 GLY B O 1 ATOM 3783 N N . PRO B 1 49 ? -20.724 18.700 8.746 1.00 76.64 ? 22 PRO B N 1 ATOM 3784 C CA . PRO B 1 49 ? -21.932 19.346 8.170 1.00 70.86 ? 22 PRO B CA 1 ATOM 3785 C C . PRO B 1 49 ? -21.773 20.761 7.557 1.00 68.89 ? 22 PRO B C 1 ATOM 3786 O O . PRO B 1 49 ? -20.909 21.566 7.962 1.00 61.37 ? 22 PRO B O 1 ATOM 3787 C CB . PRO B 1 49 ? -22.906 19.379 9.355 1.00 72.54 ? 22 PRO B CB 1 ATOM 3788 C CG . PRO B 1 49 ? -22.534 18.176 10.164 1.00 71.58 ? 22 PRO B CG 1 ATOM 3789 C CD . PRO B 1 49 ? -21.047 17.985 10.003 1.00 73.47 ? 22 PRO B CD 1 ATOM 3790 N N . ASP B 1 50 ? -22.626 21.030 6.568 1.00 67.31 ? 23 ASP B N 1 ATOM 3791 C CA . ASP B 1 50 ? -22.598 22.281 5.804 1.00 69.93 ? 23 ASP B CA 1 ATOM 3792 C C . ASP B 1 50 ? -22.944 23.524 6.640 1.00 63.16 ? 23 ASP B C 1 ATOM 3793 O O . ASP B 1 50 ? -22.100 24.392 6.806 1.00 63.50 ? 23 ASP B O 1 ATOM 3794 C CB . ASP B 1 50 ? -23.529 22.188 4.578 1.00 74.24 ? 23 ASP B CB 1 ATOM 3795 C CG . ASP B 1 50 ? -22.985 21.256 3.488 1.00 79.90 ? 23 ASP B CG 1 ATOM 3796 O OD1 . ASP B 1 50 ? -21.747 21.109 3.371 1.00 81.17 ? 23 ASP B OD1 1 ATOM 3797 O OD2 . ASP B 1 50 ? -23.800 20.680 2.732 1.00 83.31 ? 23 ASP B OD2 1 ATOM 3798 N N . GLN B 1 51 ? -24.178 23.598 7.145 1.00 56.58 ? 24 GLN B N 1 ATOM 3799 C CA . GLN B 1 51 ? -24.653 24.727 7.963 1.00 53.37 ? 24 GLN B CA 1 ATOM 3800 C C . GLN B 1 51 ? -24.088 24.605 9.373 1.00 48.38 ? 24 GLN B C 1 ATOM 3801 O O . GLN B 1 51 ? -24.282 23.592 10.008 1.00 44.43 ? 24 GLN B O 1 ATOM 3802 C CB . GLN B 1 51 ? -26.180 24.684 8.045 1.00 55.25 ? 24 GLN B CB 1 ATOM 3803 C CG . GLN B 1 51 ? -26.860 26.001 8.397 1.00 60.24 ? 24 GLN B CG 1 ATOM 3804 C CD . GLN B 1 51 ? -28.368 25.861 8.618 1.00 59.94 ? 24 GLN B CD 1 ATOM 3805 O OE1 . GLN B 1 51 ? -28.881 24.764 8.836 1.00 57.43 ? 24 GLN B OE1 1 ATOM 3806 N NE2 . GLN B 1 51 ? -29.075 26.988 8.611 1.00 60.03 ? 24 GLN B NE2 1 ATOM 3807 N N . ARG B 1 52 ? -23.427 25.638 9.876 1.00 43.08 ? 25 ARG B N 1 ATOM 3808 C CA . ARG B 1 52 ? -22.733 25.539 11.150 1.00 43.55 ? 25 ARG B CA 1 ATOM 3809 C C . ARG B 1 52 ? -22.369 26.927 11.614 1.00 41.40 ? 25 ARG B C 1 ATOM 3810 O O . ARG B 1 52 ? -22.495 27.874 10.866 1.00 40.95 ? 25 ARG B O 1 ATOM 3811 C CB . ARG B 1 52 ? -21.469 24.719 10.989 1.00 45.02 ? 25 ARG B CB 1 ATOM 3812 C CG . ARG B 1 52 ? -20.492 25.327 9.993 1.00 53.30 ? 25 ARG B CG 1 ATOM 3813 C CD . ARG B 1 52 ? -19.132 24.651 10.054 1.00 53.82 ? 25 ARG B CD 1 ATOM 3814 N NE . ARG B 1 52 ? -19.152 23.333 9.439 1.00 53.63 ? 25 ARG B NE 1 ATOM 3815 C CZ . ARG B 1 52 ? -18.178 22.437 9.542 1.00 54.92 ? 25 ARG B CZ 1 ATOM 3816 N NH1 . ARG B 1 52 ? -17.075 22.688 10.253 1.00 58.38 ? 25 ARG B NH1 1 ATOM 3817 N NH2 . ARG B 1 52 ? -18.315 21.269 8.933 1.00 58.62 ? 25 ARG B NH2 1 ATOM 3818 N N . ALA B 1 53 ? -21.980 27.047 12.877 1.00 38.20 ? 26 ALA B N 1 ATOM 3819 C CA . ALA B 1 53 ? -21.376 28.253 13.376 1.00 37.24 ? 26 ALA B CA 1 ATOM 3820 C C . ALA B 1 53 ? -19.994 27.856 13.812 1.00 40.68 ? 26 ALA B C 1 ATOM 3821 O O . ALA B 1 53 ? -19.833 26.941 14.609 1.00 39.26 ? 26 ALA B O 1 ATOM 3822 C CB . ALA B 1 53 ? -22.161 28.847 14.527 1.00 36.59 ? 26 ALA B CB 1 ATOM 3823 N N . GLN B 1 54 ? -19.004 28.551 13.268 1.00 42.76 ? 27 GLN B N 1 ATOM 3824 C CA . GLN B 1 54 ? -17.626 28.144 13.378 1.00 47.12 ? 27 GLN B CA 1 ATOM 3825 C C . GLN B 1 54 ? -16.714 29.356 13.451 1.00 48.53 ? 27 GLN B C 1 ATOM 3826 O O . GLN B 1 54 ? -16.916 30.352 12.751 1.00 45.30 ? 27 GLN B O 1 ATOM 3827 C CB . GLN B 1 54 ? -17.242 27.268 12.203 1.00 51.19 ? 27 GLN B CB 1 ATOM 3828 C CG . GLN B 1 54 ? -15.755 27.010 12.099 1.00 57.98 ? 27 GLN B CG 1 ATOM 3829 C CD . GLN B 1 54 ? -15.423 25.591 11.701 1.00 66.64 ? 27 GLN B CD 1 ATOM 3830 O OE1 . GLN B 1 54 ? -16.283 24.845 11.246 1.00 74.81 ? 27 GLN B OE1 1 ATOM 3831 N NE2 . GLN B 1 54 ? -14.162 25.207 11.879 1.00 71.79 ? 27 GLN B NE2 1 ATOM 3832 N N . LYS B 1 55 ? -15.735 29.270 14.344 1.00 46.65 ? 28 LYS B N 1 ATOM 3833 C CA . LYS B 1 55 ? -14.696 30.271 14.438 1.00 48.40 ? 28 LYS B CA 1 ATOM 3834 C C . LYS B 1 55 ? -13.438 29.655 15.012 1.00 47.57 ? 28 LYS B C 1 ATOM 3835 O O . LYS B 1 55 ? -13.486 28.949 16.027 1.00 45.71 ? 28 LYS B O 1 ATOM 3836 C CB . LYS B 1 55 ? -15.151 31.432 15.293 1.00 53.57 ? 28 LYS B CB 1 ATOM 3837 C CG . LYS B 1 55 ? -14.148 32.562 15.320 1.00 57.10 ? 28 LYS B CG 1 ATOM 3838 C CD . LYS B 1 55 ? -14.729 33.781 16.005 1.00 62.72 ? 28 LYS B CD 1 ATOM 3839 C CE . LYS B 1 55 ? -13.702 34.900 16.073 1.00 66.46 ? 28 LYS B CE 1 ATOM 3840 N NZ . LYS B 1 55 ? -14.301 36.102 16.713 1.00 69.75 ? 28 LYS B NZ 1 ATOM 3841 N N . LYS B 1 56 ? -12.313 29.927 14.357 1.00 42.46 ? 29 LYS B N 1 ATOM 3842 C CA . LYS B 1 56 ? -11.039 29.339 14.734 1.00 42.72 ? 29 LYS B CA 1 ATOM 3843 C C . LYS B 1 56 ? -10.567 29.932 16.070 1.00 40.23 ? 29 LYS B C 1 ATOM 3844 O O . LYS B 1 56 ? -11.003 31.017 16.495 1.00 37.55 ? 29 LYS B O 1 ATOM 3845 C CB . LYS B 1 56 ? -9.986 29.537 13.636 1.00 44.14 ? 29 LYS B CB 1 ATOM 3846 N N . GLY B 1 57 ? -9.710 29.174 16.742 1.00 41.06 ? 30 GLY B N 1 ATOM 3847 C CA . GLY B 1 57 ? -9.149 29.576 18.040 1.00 41.32 ? 30 GLY B CA 1 ATOM 3848 C C . GLY B 1 57 ? -8.045 28.625 18.455 1.00 38.96 ? 30 GLY B C 1 ATOM 3849 O O . GLY B 1 57 ? -7.762 27.645 17.763 1.00 38.13 ? 30 GLY B O 1 ATOM 3850 N N . ASP B 1 58 ? -7.422 28.903 19.593 1.00 41.73 ? 31 ASP B N 1 ATOM 3851 C CA . ASP B 1 58 ? -6.392 28.011 20.131 1.00 41.54 ? 31 ASP B CA 1 ATOM 3852 C C . ASP B 1 58 ? -7.008 26.765 20.736 1.00 39.26 ? 31 ASP B C 1 ATOM 3853 O O . ASP B 1 58 ? -6.442 25.675 20.639 1.00 41.38 ? 31 ASP B O 1 ATOM 3854 C CB . ASP B 1 58 ? -5.594 28.740 21.194 1.00 45.69 ? 31 ASP B CB 1 ATOM 3855 C CG . ASP B 1 58 ? -4.912 29.966 20.644 1.00 46.97 ? 31 ASP B CG 1 ATOM 3856 O OD1 . ASP B 1 58 ? -4.184 29.808 19.640 1.00 50.88 ? 31 ASP B OD1 1 ATOM 3857 O OD2 . ASP B 1 58 ? -5.137 31.072 21.188 1.00 50.04 ? 31 ASP B OD2 1 ATOM 3858 N N . ILE B 1 59 ? -8.188 26.930 21.331 1.00 39.24 ? 32 ILE B N 1 ATOM 3859 C CA . ILE B 1 59 ? -8.940 25.820 21.925 1.00 39.48 ? 32 ILE B CA 1 ATOM 3860 C C . ILE B 1 59 ? -10.382 25.863 21.431 1.00 35.81 ? 32 ILE B C 1 ATOM 3861 O O . ILE B 1 59 ? -11.034 26.886 21.551 1.00 36.73 ? 32 ILE B O 1 ATOM 3862 C CB . ILE B 1 59 ? -8.914 25.921 23.460 1.00 40.09 ? 32 ILE B CB 1 ATOM 3863 C CG1 . ILE B 1 59 ? -7.503 25.659 23.972 1.00 42.68 ? 32 ILE B CG1 1 ATOM 3864 C CG2 . ILE B 1 59 ? -9.842 24.907 24.097 1.00 39.36 ? 32 ILE B CG2 1 ATOM 3865 C CD1 . ILE B 1 59 ? -7.245 26.311 25.307 1.00 45.81 ? 32 ILE B CD1 1 ATOM 3866 N N . ILE B 1 60 ? -10.860 24.744 20.895 1.00 36.35 ? 33 ILE B N 1 ATOM 3867 C CA . ILE B 1 60 ? -12.178 24.668 20.258 1.00 39.14 ? 33 ILE B CA 1 ATOM 3868 C C . ILE B 1 60 ? -13.235 23.974 21.144 1.00 34.87 ? 33 ILE B C 1 ATOM 3869 O O . ILE B 1 60 ? -13.033 22.853 21.568 1.00 33.16 ? 33 ILE B O 1 ATOM 3870 C CB . ILE B 1 60 ? -12.095 23.880 18.929 1.00 39.94 ? 33 ILE B CB 1 ATOM 3871 C CG1 . ILE B 1 60 ? -10.947 24.395 18.035 1.00 41.31 ? 33 ILE B CG1 1 ATOM 3872 C CG2 . ILE B 1 60 ? -13.420 23.951 18.172 1.00 38.93 ? 33 ILE B CG2 1 ATOM 3873 C CD1 . ILE B 1 60 ? -11.054 25.850 17.652 1.00 41.77 ? 33 ILE B CD1 1 ATOM 3874 N N . LEU B 1 61 ? -14.350 24.657 21.386 1.00 34.02 ? 34 LEU B N 1 ATOM 3875 C CA . LEU B 1 61 ? -15.548 24.046 21.971 1.00 33.21 ? 34 LEU B CA 1 ATOM 3876 C C . LEU B 1 61 ? -16.541 23.622 20.895 1.00 31.85 ? 34 LEU B C 1 ATOM 3877 O O . LEU B 1 61 ? -16.928 24.418 20.059 1.00 32.75 ? 34 LEU B O 1 ATOM 3878 C CB . LEU B 1 61 ? -16.270 25.010 22.909 1.00 35.39 ? 34 LEU B CB 1 ATOM 3879 C CG . LEU B 1 61 ? -15.478 25.684 24.030 1.00 39.09 ? 34 LEU B CG 1 ATOM 3880 C CD1 . LEU B 1 61 ? -16.413 26.134 25.138 1.00 38.73 ? 34 LEU B CD1 1 ATOM 3881 C CD2 . LEU B 1 61 ? -14.410 24.795 24.597 1.00 42.48 ? 34 LEU B CD2 1 ATOM 3882 N N . GLY B 1 62 ? -16.946 22.360 20.927 1.00 30.20 ? 35 GLY B N 1 ATOM 3883 C CA . GLY B 1 62 ? -18.078 21.885 20.157 1.00 29.70 ? 35 GLY B CA 1 ATOM 3884 C C . GLY B 1 62 ? -19.379 22.367 20.770 1.00 28.67 ? 35 GLY B C 1 ATOM 3885 O O . GLY B 1 62 ? -19.461 22.608 21.967 1.00 29.90 ? 35 GLY B O 1 ATOM 3886 N N . GLY B 1 63 ? -20.397 22.507 19.936 1.00 27.72 ? 36 GLY B N 1 ATOM 3887 C CA . GLY B 1 63 ? -21.738 22.878 20.381 1.00 28.98 ? 36 GLY B CA 1 ATOM 3888 C C . GLY B 1 63 ? -22.791 22.093 19.607 1.00 28.38 ? 36 GLY B C 1 ATOM 3889 O O . GLY B 1 63 ? -22.619 21.809 18.426 1.00 26.91 ? 36 GLY B O 1 ATOM 3890 N N . LEU B 1 64 ? -23.874 21.731 20.291 1.00 29.52 ? 37 LEU B N 1 ATOM 3891 C CA . LEU B 1 64 ? -24.995 21.043 19.677 1.00 28.19 ? 37 LEU B CA 1 ATOM 3892 C C . LEU B 1 64 ? -26.279 21.692 20.154 1.00 28.65 ? 37 LEU B C 1 ATOM 3893 O O . LEU B 1 64 ? -26.526 21.762 21.371 1.00 27.39 ? 37 LEU B O 1 ATOM 3894 C CB . LEU B 1 64 ? -24.980 19.585 20.067 1.00 28.06 ? 37 LEU B CB 1 ATOM 3895 C CG . LEU B 1 64 ? -23.804 18.757 19.510 1.00 29.48 ? 37 LEU B CG 1 ATOM 3896 C CD1 . LEU B 1 64 ? -23.762 17.379 20.170 1.00 29.55 ? 37 LEU B CD1 1 ATOM 3897 C CD2 . LEU B 1 64 ? -23.813 18.653 17.990 1.00 28.67 ? 37 LEU B CD2 1 ATOM 3898 N N . PHE B 1 65 ? -27.110 22.149 19.205 1.00 25.33 ? 38 PHE B N 1 ATOM 3899 C CA . PHE B 1 65 ? -28.368 22.836 19.542 1.00 25.57 ? 38 PHE B CA 1 ATOM 3900 C C . PHE B 1 65 ? -29.456 22.467 18.535 1.00 25.02 ? 38 PHE B C 1 ATOM 3901 O O . PHE B 1 65 ? -29.148 22.158 17.391 1.00 24.99 ? 38 PHE B O 1 ATOM 3902 C CB . PHE B 1 65 ? -28.208 24.361 19.520 1.00 25.83 ? 38 PHE B CB 1 ATOM 3903 C CG . PHE B 1 65 ? -27.210 24.876 20.504 1.00 27.08 ? 38 PHE B CG 1 ATOM 3904 C CD1 . PHE B 1 65 ? -25.859 24.939 20.168 1.00 27.69 ? 38 PHE B CD1 1 ATOM 3905 C CD2 . PHE B 1 65 ? -27.607 25.257 21.771 1.00 27.02 ? 38 PHE B CD2 1 ATOM 3906 C CE1 . PHE B 1 65 ? -24.926 25.349 21.090 1.00 26.63 ? 38 PHE B CE1 1 ATOM 3907 C CE2 . PHE B 1 65 ? -26.680 25.689 22.691 1.00 26.98 ? 38 PHE B CE2 1 ATOM 3908 C CZ . PHE B 1 65 ? -25.340 25.726 22.346 1.00 27.17 ? 38 PHE B CZ 1 ATOM 3909 N N . PRO B 1 66 ? -30.719 22.465 18.974 1.00 25.55 ? 39 PRO B N 1 ATOM 3910 C CA . PRO B 1 66 ? -31.839 22.117 18.110 1.00 27.68 ? 39 PRO B CA 1 ATOM 3911 C C . PRO B 1 66 ? -32.353 23.361 17.418 1.00 27.02 ? 39 PRO B C 1 ATOM 3912 O O . PRO B 1 66 ? -33.299 23.999 17.893 1.00 28.81 ? 39 PRO B O 1 ATOM 3913 C CB . PRO B 1 66 ? -32.853 21.540 19.085 1.00 27.70 ? 39 PRO B CB 1 ATOM 3914 C CG . PRO B 1 66 ? -32.589 22.260 20.368 1.00 26.14 ? 39 PRO B CG 1 ATOM 3915 C CD . PRO B 1 66 ? -31.158 22.676 20.364 1.00 26.28 ? 39 PRO B CD 1 ATOM 3916 N N . ILE B 1 67 ? -31.676 23.725 16.334 1.00 27.74 ? 40 ILE B N 1 ATOM 3917 C CA . ILE B 1 67 ? -32.038 24.897 15.530 1.00 29.63 ? 40 ILE B CA 1 ATOM 3918 C C . ILE B 1 67 ? -33.339 24.602 14.762 1.00 31.31 ? 40 ILE B C 1 ATOM 3919 O O . ILE B 1 67 ? -34.114 25.514 14.477 1.00 31.01 ? 40 ILE B O 1 ATOM 3920 C CB . ILE B 1 67 ? -30.894 25.296 14.596 1.00 30.72 ? 40 ILE B CB 1 ATOM 3921 C CG1 . ILE B 1 67 ? -29.599 25.519 15.405 1.00 28.73 ? 40 ILE B CG1 1 ATOM 3922 C CG2 . ILE B 1 67 ? -31.238 26.561 13.789 1.00 32.85 ? 40 ILE B CG2 1 ATOM 3923 C CD1 . ILE B 1 67 ? -29.731 26.479 16.553 1.00 26.60 ? 40 ILE B CD1 1 ATOM 3924 N N . HIS B 1 68 ? -33.585 23.326 14.468 1.00 29.82 ? 41 HIS B N 1 ATOM 3925 C CA . HIS B 1 68 ? -34.904 22.904 14.038 1.00 33.39 ? 41 HIS B CA 1 ATOM 3926 C C . HIS B 1 68 ? -35.490 21.920 14.999 1.00 32.83 ? 41 HIS B C 1 ATOM 3927 O O . HIS B 1 68 ? -34.756 21.201 15.685 1.00 31.21 ? 41 HIS B O 1 ATOM 3928 C CB . HIS B 1 68 ? -34.821 22.265 12.667 1.00 33.25 ? 41 HIS B CB 1 ATOM 3929 C CG . HIS B 1 68 ? -34.354 23.201 11.616 1.00 35.82 ? 41 HIS B CG 1 ATOM 3930 N ND1 . HIS B 1 68 ? -33.017 23.454 11.397 1.00 34.83 ? 41 HIS B ND1 1 ATOM 3931 C CD2 . HIS B 1 68 ? -35.039 23.932 10.703 1.00 34.58 ? 41 HIS B CD2 1 ATOM 3932 C CE1 . HIS B 1 68 ? -32.897 24.304 10.396 1.00 34.90 ? 41 HIS B CE1 1 ATOM 3933 N NE2 . HIS B 1 68 ? -34.106 24.604 9.956 1.00 36.61 ? 41 HIS B NE2 1 ATOM 3934 N N . PHE B 1 69 ? -36.813 21.856 15.015 1.00 32.31 ? 42 PHE B N 1 ATOM 3935 C CA . PHE B 1 69 ? -37.537 20.967 15.926 1.00 33.71 ? 42 PHE B CA 1 ATOM 3936 C C . PHE B 1 69 ? -37.530 19.513 15.515 1.00 35.51 ? 42 PHE B C 1 ATOM 3937 O O . PHE B 1 69 ? -37.817 18.651 16.315 1.00 37.73 ? 42 PHE B O 1 ATOM 3938 C CB . PHE B 1 69 ? -38.991 21.400 16.070 1.00 33.99 ? 42 PHE B CB 1 ATOM 3939 C CG . PHE B 1 69 ? -39.188 22.569 16.986 1.00 35.37 ? 42 PHE B CG 1 ATOM 3940 C CD1 . PHE B 1 69 ? -38.843 22.489 18.319 1.00 35.63 ? 42 PHE B CD1 1 ATOM 3941 C CD2 . PHE B 1 69 ? -39.731 23.755 16.516 1.00 36.56 ? 42 PHE B CD2 1 ATOM 3942 C CE1 . PHE B 1 69 ? -39.043 23.558 19.175 1.00 34.66 ? 42 PHE B CE1 1 ATOM 3943 C CE2 . PHE B 1 69 ? -39.900 24.839 17.363 1.00 34.72 ? 42 PHE B CE2 1 ATOM 3944 C CZ . PHE B 1 69 ? -39.569 24.736 18.691 1.00 35.82 ? 42 PHE B CZ 1 ATOM 3945 N N . GLY B 1 70 ? -37.228 19.233 14.256 1.00 36.91 ? 43 GLY B N 1 ATOM 3946 C CA . GLY B 1 70 ? -37.345 17.889 13.747 1.00 34.77 ? 43 GLY B CA 1 ATOM 3947 C C . GLY B 1 70 ? -36.843 17.792 12.329 1.00 38.48 ? 43 GLY B C 1 ATOM 3948 O O . GLY B 1 70 ? -36.204 18.705 11.793 1.00 39.31 ? 43 GLY B O 1 ATOM 3949 N N . VAL B 1 71 ? -37.170 16.677 11.720 1.00 41.29 ? 44 VAL B N 1 ATOM 3950 C CA . VAL B 1 71 ? -36.675 16.315 10.418 1.00 43.42 ? 44 VAL B CA 1 ATOM 3951 C C . VAL B 1 71 ? -37.878 16.005 9.510 1.00 45.95 ? 44 VAL B C 1 ATOM 3952 O O . VAL B 1 71 ? -38.966 15.638 9.992 1.00 42.21 ? 44 VAL B O 1 ATOM 3953 C CB . VAL B 1 71 ? -35.744 15.123 10.596 1.00 46.53 ? 44 VAL B CB 1 ATOM 3954 C CG1 . VAL B 1 71 ? -35.869 14.149 9.467 1.00 52.41 ? 44 VAL B CG1 1 ATOM 3955 C CG2 . VAL B 1 71 ? -34.314 15.602 10.761 1.00 49.28 ? 44 VAL B CG2 1 ATOM 3956 N N . ALA B 1 72 ? -37.684 16.196 8.204 1.00 50.57 ? 45 ALA B N 1 ATOM 3957 C CA . ALA B 1 72 ? -38.769 16.057 7.236 1.00 55.34 ? 45 ALA B CA 1 ATOM 3958 C C . ALA B 1 72 ? -39.150 14.609 7.136 1.00 58.99 ? 45 ALA B C 1 ATOM 3959 O O . ALA B 1 72 ? -38.299 13.745 6.893 1.00 61.88 ? 45 ALA B O 1 ATOM 3960 C CB . ALA B 1 72 ? -38.357 16.548 5.868 1.00 56.48 ? 45 ALA B CB 1 ATOM 3961 N N . ALA B 1 73 ? -40.443 14.361 7.294 1.00 60.75 ? 46 ALA B N 1 ATOM 3962 C CA . ALA B 1 73 ? -40.991 13.015 7.274 1.00 67.89 ? 46 ALA B CA 1 ATOM 3963 C C . ALA B 1 73 ? -41.038 12.492 5.823 1.00 67.07 ? 46 ALA B C 1 ATOM 3964 O O . ALA B 1 73 ? -42.094 12.436 5.196 1.00 73.26 ? 46 ALA B O 1 ATOM 3965 C CB . ALA B 1 73 ? -42.379 12.999 7.931 1.00 64.04 ? 46 ALA B CB 1 ATOM 3966 N N . LYS B 1 74 ? -39.867 12.142 5.294 1.00 62.97 ? 47 LYS B N 1 ATOM 3967 C CA . LYS B 1 74 ? -39.759 11.422 4.029 1.00 67.42 ? 47 LYS B CA 1 ATOM 3968 C C . LYS B 1 74 ? -39.404 10.028 4.495 1.00 71.06 ? 47 LYS B C 1 ATOM 3969 O O . LYS B 1 74 ? -38.219 9.699 4.636 1.00 75.79 ? 47 LYS B O 1 ATOM 3970 C CB . LYS B 1 74 ? -38.648 12.006 3.113 1.00 63.22 ? 47 LYS B CB 1 ATOM 3971 C CG . LYS B 1 74 ? -37.829 10.973 2.321 1.00 59.64 ? 47 LYS B CG 1 ATOM 3972 C CD . LYS B 1 74 ? -36.616 11.616 1.637 1.00 59.98 ? 47 LYS B CD 1 ATOM 3973 C CE . LYS B 1 74 ? -36.802 11.733 0.124 1.00 59.67 ? 47 LYS B CE 1 ATOM 3974 N NZ . LYS B 1 74 ? -35.698 12.544 -0.476 1.00 61.00 ? 47 LYS B NZ 1 ATOM 3975 N N . ASP B 1 75 ? -40.416 9.229 4.822 1.00 67.63 ? 48 ASP B N 1 ATOM 3976 C CA . ASP B 1 75 ? -40.150 7.840 5.197 1.00 69.77 ? 48 ASP B CA 1 ATOM 3977 C C . ASP B 1 75 ? -39.410 7.156 4.033 1.00 75.54 ? 48 ASP B C 1 ATOM 3978 O O . ASP B 1 75 ? -39.846 7.240 2.872 1.00 71.37 ? 48 ASP B O 1 ATOM 3979 C CB . ASP B 1 75 ? -41.446 7.096 5.566 1.00 67.77 ? 48 ASP B CB 1 ATOM 3980 C CG . ASP B 1 75 ? -41.584 6.870 7.062 1.00 66.50 ? 48 ASP B CG 1 ATOM 3981 O OD1 . ASP B 1 75 ? -42.336 5.929 7.463 1.00 65.68 ? 48 ASP B OD1 1 ATOM 3982 O OD2 . ASP B 1 75 ? -40.931 7.614 7.840 1.00 61.79 ? 48 ASP B OD2 1 ATOM 3983 N N . GLN B 1 76 ? -38.277 6.529 4.347 1.00 75.38 ? 49 GLN B N 1 ATOM 3984 C CA . GLN B 1 76 ? -37.389 6.007 3.320 1.00 77.28 ? 49 GLN B CA 1 ATOM 3985 C C . GLN B 1 76 ? -37.768 4.571 2.997 1.00 77.91 ? 49 GLN B C 1 ATOM 3986 O O . GLN B 1 76 ? -37.564 3.662 3.805 1.00 70.22 ? 49 GLN B O 1 ATOM 3987 C CB . GLN B 1 76 ? -35.922 6.052 3.756 1.00 81.31 ? 49 GLN B CB 1 ATOM 3988 C CG . GLN B 1 76 ? -35.229 7.391 3.567 1.00 84.52 ? 49 GLN B CG 1 ATOM 3989 C CD . GLN B 1 76 ? -35.069 8.161 4.871 1.00 86.38 ? 49 GLN B CD 1 ATOM 3990 O OE1 . GLN B 1 76 ? -34.967 7.573 5.960 1.00 79.43 ? 49 GLN B OE1 1 ATOM 3991 N NE2 . GLN B 1 76 ? -35.022 9.483 4.766 1.00 85.55 ? 49 GLN B NE2 1 ATOM 3992 N N . ASP B 1 77 ? -38.312 4.383 1.800 1.00 71.50 ? 50 ASP B N 1 ATOM 3993 C CA . ASP B 1 77 ? -38.603 3.056 1.288 1.00 67.25 ? 50 ASP B CA 1 ATOM 3994 C C . ASP B 1 77 ? -37.355 2.420 0.651 1.00 58.19 ? 50 ASP B C 1 ATOM 3995 O O . ASP B 1 77 ? -37.384 1.253 0.287 1.00 62.75 ? 50 ASP B O 1 ATOM 3996 C CB . ASP B 1 77 ? -39.779 3.107 0.302 1.00 67.46 ? 50 ASP B CB 1 ATOM 3997 C CG . ASP B 1 77 ? -39.571 4.115 -0.820 1.00 65.43 ? 50 ASP B CG 1 ATOM 3998 O OD1 . ASP B 1 77 ? -38.424 4.551 -1.048 1.00 66.33 ? 50 ASP B OD1 1 ATOM 3999 O OD2 . ASP B 1 77 ? -40.562 4.468 -1.496 1.00 67.51 ? 50 ASP B OD2 1 ATOM 4000 N N . LEU B 1 78 ? -36.272 3.191 0.537 1.00 50.58 ? 51 LEU B N 1 ATOM 4001 C CA . LEU B 1 78 ? -34.985 2.725 0.012 1.00 50.69 ? 51 LEU B CA 1 ATOM 4002 C C . LEU B 1 78 ? -35.047 2.133 -1.394 1.00 55.65 ? 51 LEU B C 1 ATOM 4003 O O . LEU B 1 78 ? -34.381 1.128 -1.684 1.00 56.29 ? 51 LEU B O 1 ATOM 4004 C CB . LEU B 1 78 ? -34.362 1.703 0.958 1.00 49.38 ? 51 LEU B CB 1 ATOM 4005 C CG . LEU B 1 78 ? -34.158 2.169 2.387 1.00 48.87 ? 51 LEU B CG 1 ATOM 4006 C CD1 . LEU B 1 78 ? -33.674 1.000 3.226 1.00 49.21 ? 51 LEU B CD1 1 ATOM 4007 C CD2 . LEU B 1 78 ? -33.157 3.306 2.409 1.00 48.34 ? 51 LEU B CD2 1 ATOM 4008 N N . LYS B 1 79 ? -35.850 2.755 -2.253 1.00 58.17 ? 52 LYS B N 1 ATOM 4009 C CA . LYS B 1 79 ? -35.831 2.439 -3.682 1.00 59.25 ? 52 LYS B CA 1 ATOM 4010 C C . LYS B 1 79 ? -34.649 3.065 -4.390 1.00 58.98 ? 52 LYS B C 1 ATOM 4011 O O . LYS B 1 79 ? -34.184 2.544 -5.401 1.00 58.08 ? 52 LYS B O 1 ATOM 4012 C CB . LYS B 1 79 ? -37.130 2.886 -4.322 1.00 61.05 ? 52 LYS B CB 1 ATOM 4013 C CG . LYS B 1 79 ? -38.267 1.968 -3.932 1.00 64.32 ? 52 LYS B CG 1 ATOM 4014 C CD . LYS B 1 79 ? -39.634 2.567 -4.229 1.00 66.32 ? 52 LYS B CD 1 ATOM 4015 C CE . LYS B 1 79 ? -40.390 1.726 -5.260 1.00 65.67 ? 52 LYS B CE 1 ATOM 4016 N NZ . LYS B 1 79 ? -41.106 0.584 -4.617 1.00 66.88 ? 52 LYS B NZ 1 ATOM 4017 N N . SER B 1 80 ? -34.173 4.186 -3.855 1.00 56.10 ? 53 SER B N 1 ATOM 4018 C CA . SER B 1 80 ? -32.978 4.855 -4.354 1.00 59.98 ? 53 SER B CA 1 ATOM 4019 C C . SER B 1 80 ? -32.091 5.152 -3.158 1.00 60.85 ? 53 SER B C 1 ATOM 4020 O O . SER B 1 80 ? -32.542 5.022 -2.018 1.00 60.39 ? 53 SER B O 1 ATOM 4021 C CB . SER B 1 80 ? -33.350 6.143 -5.082 1.00 61.94 ? 53 SER B CB 1 ATOM 4022 O OG . SER B 1 80 ? -34.303 6.881 -4.329 1.00 66.00 ? 53 SER B OG 1 ATOM 4023 N N . ARG B 1 81 ? -30.846 5.552 -3.414 1.00 61.17 ? 54 ARG B N 1 ATOM 4024 C CA . ARG B 1 81 ? -29.869 5.737 -2.350 1.00 62.36 ? 54 ARG B CA 1 ATOM 4025 C C . ARG B 1 81 ? -30.359 6.810 -1.382 1.00 60.32 ? 54 ARG B C 1 ATOM 4026 O O . ARG B 1 81 ? -30.728 7.895 -1.816 1.00 59.62 ? 54 ARG B O 1 ATOM 4027 C CB . ARG B 1 81 ? -28.505 6.121 -2.914 1.00 65.27 ? 54 ARG B CB 1 ATOM 4028 C CG . ARG B 1 81 ? -27.405 6.248 -1.857 1.00 72.62 ? 54 ARG B CG 1 ATOM 4029 C CD . ARG B 1 81 ? -25.981 6.195 -2.455 1.00 76.51 ? 54 ARG B CD 1 ATOM 4030 N NE . ARG B 1 81 ? -25.959 6.726 -3.822 1.00 83.80 ? 54 ARG B NE 1 ATOM 4031 C CZ . ARG B 1 81 ? -25.947 6.006 -4.950 1.00 90.05 ? 54 ARG B CZ 1 ATOM 4032 N NH1 . ARG B 1 81 ? -25.921 4.674 -4.935 1.00 88.83 ? 54 ARG B NH1 1 ATOM 4033 N NH2 . ARG B 1 81 ? -25.953 6.637 -6.123 1.00 93.76 ? 54 ARG B NH2 1 ATOM 4034 N N . PRO B 1 82 ? -30.379 6.509 -0.065 1.00 58.35 ? 55 PRO B N 1 ATOM 4035 C CA . PRO B 1 82 ? -30.905 7.547 0.828 1.00 56.65 ? 55 PRO B CA 1 ATOM 4036 C C . PRO B 1 82 ? -30.102 8.847 0.723 1.00 54.00 ? 55 PRO B C 1 ATOM 4037 O O . PRO B 1 82 ? -28.874 8.817 0.694 1.00 51.85 ? 55 PRO B O 1 ATOM 4038 C CB . PRO B 1 82 ? -30.766 6.927 2.225 1.00 55.83 ? 55 PRO B CB 1 ATOM 4039 C CG . PRO B 1 82 ? -30.504 5.479 1.996 1.00 54.47 ? 55 PRO B CG 1 ATOM 4040 C CD . PRO B 1 82 ? -29.762 5.412 0.702 1.00 56.75 ? 55 PRO B CD 1 ATOM 4041 N N . GLU B 1 83 ? -30.813 9.958 0.611 1.00 54.46 ? 56 GLU B N 1 ATOM 4042 C CA . GLU B 1 83 ? -30.209 11.294 0.583 1.00 58.80 ? 56 GLU B CA 1 ATOM 4043 C C . GLU B 1 83 ? -30.213 11.840 2.005 1.00 57.11 ? 56 GLU B C 1 ATOM 4044 O O . GLU B 1 83 ? -30.905 11.316 2.876 1.00 55.05 ? 56 GLU B O 1 ATOM 4045 C CB . GLU B 1 83 ? -31.000 12.235 -0.356 1.00 58.63 ? 56 GLU B CB 1 ATOM 4046 C CG . GLU B 1 83 ? -30.215 12.751 -1.566 1.00 60.15 ? 56 GLU B CG 1 ATOM 4047 C CD . GLU B 1 83 ? -30.978 12.657 -2.898 1.00 63.41 ? 56 GLU B CD 1 ATOM 4048 O OE1 . GLU B 1 83 ? -31.985 11.899 -3.022 1.00 61.04 ? 56 GLU B OE1 1 ATOM 4049 O OE2 . GLU B 1 83 ? -30.543 13.334 -3.859 1.00 61.64 ? 56 GLU B OE2 1 ATOM 4050 N N . SER B 1 84 ? -29.449 12.892 2.247 1.00 61.59 ? 57 SER B N 1 ATOM 4051 C CA . SER B 1 84 ? -29.444 13.491 3.569 1.00 66.33 ? 57 SER B CA 1 ATOM 4052 C C . SER B 1 84 ? -30.823 14.070 3.845 1.00 67.11 ? 57 SER B C 1 ATOM 4053 O O . SER B 1 84 ? -31.479 14.663 2.986 1.00 70.65 ? 57 SER B O 1 ATOM 4054 C CB . SER B 1 84 ? -28.381 14.569 3.712 1.00 66.56 ? 57 SER B CB 1 ATOM 4055 O OG . SER B 1 84 ? -28.658 15.660 2.860 1.00 72.93 ? 57 SER B OG 1 ATOM 4056 N N . VAL B 1 85 ? -31.263 13.871 5.064 1.00 64.09 ? 58 VAL B N 1 ATOM 4057 C CA . VAL B 1 85 ? -32.597 14.239 5.430 1.00 61.80 ? 58 VAL B CA 1 ATOM 4058 C C . VAL B 1 85 ? -32.691 15.755 5.712 1.00 61.24 ? 58 VAL B C 1 ATOM 4059 O O . VAL B 1 85 ? -31.721 16.385 6.131 1.00 49.62 ? 58 VAL B O 1 ATOM 4060 C CB . VAL B 1 85 ? -32.990 13.361 6.616 1.00 60.02 ? 58 VAL B CB 1 ATOM 4061 C CG1 . VAL B 1 85 ? -33.631 14.175 7.698 1.00 58.84 ? 58 VAL B CG1 1 ATOM 4062 C CG2 . VAL B 1 85 ? -33.897 12.226 6.148 1.00 61.77 ? 58 VAL B CG2 1 ATOM 4063 N N . GLU B 1 86 ? -33.871 16.321 5.477 1.00 57.54 ? 59 GLU B N 1 ATOM 4064 C CA . GLU B 1 86 ? -34.077 17.760 5.576 1.00 53.16 ? 59 GLU B CA 1 ATOM 4065 C C . GLU B 1 86 ? -34.562 18.054 6.978 1.00 47.63 ? 59 GLU B C 1 ATOM 4066 O O . GLU B 1 86 ? -35.441 17.365 7.487 1.00 47.10 ? 59 GLU B O 1 ATOM 4067 C CB . GLU B 1 86 ? -35.115 18.231 4.552 1.00 53.67 ? 59 GLU B CB 1 ATOM 4068 N N . CYS B 1 87 ? -33.986 19.072 7.605 1.00 43.44 ? 60 CYS B N 1 ATOM 4069 C CA . CYS B 1 87 ? -34.480 19.551 8.880 1.00 41.21 ? 60 CYS B CA 1 ATOM 4070 C C . CYS B 1 87 ? -35.617 20.504 8.650 1.00 42.90 ? 60 CYS B C 1 ATOM 4071 O O . CYS B 1 87 ? -35.631 21.234 7.666 1.00 44.98 ? 60 CYS B O 1 ATOM 4072 C CB . CYS B 1 87 ? -33.377 20.227 9.637 1.00 42.09 ? 60 CYS B CB 1 ATOM 4073 S SG . CYS B 1 87 ? -32.164 19.002 10.137 1.00 49.84 ? 60 CYS B SG 1 ATOM 4074 N N . ILE B 1 88 ? -36.587 20.478 9.554 1.00 41.20 ? 61 ILE B N 1 ATOM 4075 C CA . ILE B 1 88 ? -37.825 21.173 9.368 1.00 41.83 ? 61 ILE B CA 1 ATOM 4076 C C . ILE B 1 88 ? -38.281 21.836 10.665 1.00 39.47 ? 61 ILE B C 1 ATOM 4077 O O . ILE B 1 88 ? -37.976 21.350 11.758 1.00 39.29 ? 61 ILE B O 1 ATOM 4078 C CB . ILE B 1 88 ? -38.837 20.122 8.821 1.00 47.31 ? 61 ILE B CB 1 ATOM 4079 C CG1 . ILE B 1 88 ? -39.401 20.556 7.479 1.00 50.71 ? 61 ILE B CG1 1 ATOM 4080 C CG2 . ILE B 1 88 ? -39.935 19.739 9.802 1.00 47.17 ? 61 ILE B CG2 1 ATOM 4081 C CD1 . ILE B 1 88 ? -38.345 20.777 6.408 1.00 54.02 ? 61 ILE B CD1 1 ATOM 4082 N N . ARG B 1 89 ? -38.965 22.968 10.508 1.00 36.46 ? 62 ARG B N 1 ATOM 4083 C CA . ARG B 1 89 ? -39.593 23.763 11.569 1.00 39.93 ? 62 ARG B CA 1 ATOM 4084 C C . ARG B 1 89 ? -38.579 24.508 12.422 1.00 40.39 ? 62 ARG B C 1 ATOM 4085 O O . ARG B 1 89 ? -38.006 23.944 13.380 1.00 37.26 ? 62 ARG B O 1 ATOM 4086 C CB . ARG B 1 89 ? -40.481 22.911 12.452 1.00 45.91 ? 62 ARG B CB 1 ATOM 4087 C CG . ARG B 1 89 ? -41.659 22.275 11.751 1.00 53.16 ? 62 ARG B CG 1 ATOM 4088 C CD . ARG B 1 89 ? -42.396 21.439 12.755 1.00 57.81 ? 62 ARG B CD 1 ATOM 4089 N NE . ARG B 1 89 ? -43.397 22.229 13.454 1.00 61.50 ? 62 ARG B NE 1 ATOM 4090 C CZ . ARG B 1 89 ? -43.983 21.863 14.587 1.00 61.78 ? 62 ARG B CZ 1 ATOM 4091 N NH1 . ARG B 1 89 ? -43.649 20.730 15.192 1.00 60.28 ? 62 ARG B NH1 1 ATOM 4092 N NH2 . ARG B 1 89 ? -44.901 22.655 15.121 1.00 63.81 ? 62 ARG B NH2 1 ATOM 4093 N N . TYR B 1 90 ? -38.363 25.772 12.080 1.00 35.44 ? 63 TYR B N 1 ATOM 4094 C CA . TYR B 1 90 ? -37.321 26.552 12.735 1.00 37.68 ? 63 TYR B CA 1 ATOM 4095 C C . TYR B 1 90 ? -37.609 26.695 14.225 1.00 35.87 ? 63 TYR B C 1 ATOM 4096 O O . TYR B 1 90 ? -38.746 26.939 14.618 1.00 36.77 ? 63 TYR B O 1 ATOM 4097 C CB . TYR B 1 90 ? -37.134 27.921 12.066 1.00 36.12 ? 63 TYR B CB 1 ATOM 4098 C CG . TYR B 1 90 ? -35.746 28.491 12.309 1.00 35.49 ? 63 TYR B CG 1 ATOM 4099 C CD1 . TYR B 1 90 ? -34.673 28.067 11.565 1.00 34.37 ? 63 TYR B CD1 1 ATOM 4100 C CD2 . TYR B 1 90 ? -35.507 29.447 13.307 1.00 34.38 ? 63 TYR B CD2 1 ATOM 4101 C CE1 . TYR B 1 90 ? -33.409 28.572 11.785 1.00 35.36 ? 63 TYR B CE1 1 ATOM 4102 C CE2 . TYR B 1 90 ? -34.229 29.949 13.528 1.00 31.53 ? 63 TYR B CE2 1 ATOM 4103 C CZ . TYR B 1 90 ? -33.193 29.507 12.765 1.00 31.85 ? 63 TYR B CZ 1 ATOM 4104 O OH . TYR B 1 90 ? -31.902 29.959 12.939 1.00 35.73 ? 63 TYR B OH 1 ATOM 4105 N N . ASN B 1 91 ? -36.575 26.522 15.046 1.00 32.81 ? 64 ASN B N 1 ATOM 4106 C CA . ASN B 1 91 ? -36.702 26.652 16.496 1.00 32.71 ? 64 ASN B CA 1 ATOM 4107 C C . ASN B 1 91 ? -36.011 27.935 16.971 1.00 35.81 ? 64 ASN B C 1 ATOM 4108 O O . ASN B 1 91 ? -34.800 27.931 17.282 1.00 35.35 ? 64 ASN B O 1 ATOM 4109 C CB . ASN B 1 91 ? -36.070 25.441 17.168 1.00 32.35 ? 64 ASN B CB 1 ATOM 4110 C CG . ASN B 1 91 ? -36.199 25.464 18.688 1.00 31.24 ? 64 ASN B CG 1 ATOM 4111 O OD1 . ASN B 1 91 ? -36.836 26.334 19.271 1.00 32.05 ? 64 ASN B OD1 1 ATOM 4112 N ND2 . ASN B 1 91 ? -35.557 24.513 19.329 1.00 31.35 ? 64 ASN B ND2 1 ATOM 4113 N N . PHE B 1 92 ? -36.763 29.032 17.062 1.00 34.00 ? 65 PHE B N 1 ATOM 4114 C CA . PHE B 1 92 ? -36.145 30.319 17.404 1.00 35.21 ? 65 PHE B CA 1 ATOM 4115 C C . PHE B 1 92 ? -35.482 30.296 18.794 1.00 33.03 ? 65 PHE B C 1 ATOM 4116 O O . PHE B 1 92 ? -34.458 30.896 19.000 1.00 31.86 ? 65 PHE B O 1 ATOM 4117 C CB . PHE B 1 92 ? -37.174 31.458 17.302 1.00 37.18 ? 65 PHE B CB 1 ATOM 4118 C CG . PHE B 1 92 ? -37.547 31.795 15.885 1.00 38.91 ? 65 PHE B CG 1 ATOM 4119 C CD1 . PHE B 1 92 ? -36.643 32.453 15.069 1.00 38.58 ? 65 PHE B CD1 1 ATOM 4120 C CD2 . PHE B 1 92 ? -38.787 31.423 15.361 1.00 38.97 ? 65 PHE B CD2 1 ATOM 4121 C CE1 . PHE B 1 92 ? -36.960 32.749 13.758 1.00 41.37 ? 65 PHE B CE1 1 ATOM 4122 C CE2 . PHE B 1 92 ? -39.123 31.733 14.048 1.00 40.13 ? 65 PHE B CE2 1 ATOM 4123 C CZ . PHE B 1 92 ? -38.205 32.395 13.245 1.00 40.50 ? 65 PHE B CZ 1 ATOM 4124 N N . ARG B 1 93 ? -36.108 29.617 19.736 1.00 32.56 ? 66 ARG B N 1 ATOM 4125 C CA . ARG B 1 93 ? -35.593 29.537 21.078 1.00 32.28 ? 66 ARG B CA 1 ATOM 4126 C C . ARG B 1 93 ? -34.252 28.813 21.076 1.00 30.80 ? 66 ARG B C 1 ATOM 4127 O O . ARG B 1 93 ? -33.335 29.189 21.775 1.00 32.89 ? 66 ARG B O 1 ATOM 4128 C CB . ARG B 1 93 ? -36.607 28.834 21.966 1.00 32.96 ? 66 ARG B CB 1 ATOM 4129 C CG . ARG B 1 93 ? -36.201 28.747 23.424 1.00 35.57 ? 66 ARG B CG 1 ATOM 4130 C CD . ARG B 1 93 ? -37.356 28.212 24.207 1.00 36.07 ? 66 ARG B CD 1 ATOM 4131 N NE . ARG B 1 93 ? -37.013 28.014 25.600 1.00 39.19 ? 66 ARG B NE 1 ATOM 4132 C CZ . ARG B 1 93 ? -37.638 27.161 26.405 1.00 39.93 ? 66 ARG B CZ 1 ATOM 4133 N NH1 . ARG B 1 93 ? -38.643 26.411 25.949 1.00 44.95 ? 66 ARG B NH1 1 ATOM 4134 N NH2 . ARG B 1 93 ? -37.243 27.036 27.659 1.00 38.95 ? 66 ARG B NH2 1 ATOM 4135 N N . GLY B 1 94 ? -34.146 27.779 20.262 1.00 30.89 ? 67 GLY B N 1 ATOM 4136 C CA . GLY B 1 94 ? -32.912 27.027 20.133 1.00 28.85 ? 67 GLY B CA 1 ATOM 4137 C C . GLY B 1 94 ? -31.786 27.833 19.532 1.00 28.26 ? 67 GLY B C 1 ATOM 4138 O O . GLY B 1 94 ? -30.624 27.705 19.930 1.00 26.74 ? 67 GLY B O 1 ATOM 4139 N N . PHE B 1 95 ? -32.116 28.669 18.563 1.00 26.95 ? 68 PHE B N 1 ATOM 4140 C CA . PHE B 1 95 ? -31.134 29.589 17.992 1.00 29.17 ? 68 PHE B CA 1 ATOM 4141 C C . PHE B 1 95 ? -30.647 30.586 19.043 1.00 28.13 ? 68 PHE B C 1 ATOM 4142 O O . PHE B 1 95 ? -29.492 30.955 19.048 1.00 26.57 ? 68 PHE B O 1 ATOM 4143 C CB . PHE B 1 95 ? -31.722 30.338 16.794 1.00 30.13 ? 68 PHE B CB 1 ATOM 4144 C CG . PHE B 1 95 ? -30.748 31.261 16.128 1.00 31.98 ? 68 PHE B CG 1 ATOM 4145 C CD1 . PHE B 1 95 ? -29.653 30.759 15.451 1.00 32.10 ? 68 PHE B CD1 1 ATOM 4146 C CD2 . PHE B 1 95 ? -30.924 32.641 16.191 1.00 33.28 ? 68 PHE B CD2 1 ATOM 4147 C CE1 . PHE B 1 95 ? -28.741 31.612 14.856 1.00 35.37 ? 68 PHE B CE1 1 ATOM 4148 C CE2 . PHE B 1 95 ? -30.019 33.492 15.591 1.00 32.87 ? 68 PHE B CE2 1 ATOM 4149 C CZ . PHE B 1 95 ? -28.933 32.979 14.917 1.00 32.77 ? 68 PHE B CZ 1 ATOM 4150 N N . ARG B 1 96 ? -31.551 31.033 19.906 1.00 30.07 ? 69 ARG B N 1 ATOM 4151 C CA . ARG B 1 96 ? -31.189 31.892 21.023 1.00 31.20 ? 69 ARG B CA 1 ATOM 4152 C C . ARG B 1 96 ? -30.238 31.151 21.973 1.00 34.10 ? 69 ARG B C 1 ATOM 4153 O O . ARG B 1 96 ? -29.257 31.726 22.451 1.00 34.73 ? 69 ARG B O 1 ATOM 4154 C CB . ARG B 1 96 ? -32.424 32.380 21.795 1.00 31.97 ? 69 ARG B CB 1 ATOM 4155 C CG . ARG B 1 96 ? -32.062 32.945 23.166 1.00 35.16 ? 69 ARG B CG 1 ATOM 4156 C CD . ARG B 1 96 ? -33.086 33.892 23.754 1.00 34.76 ? 69 ARG B CD 1 ATOM 4157 N NE . ARG B 1 96 ? -34.467 33.458 23.664 1.00 36.62 ? 69 ARG B NE 1 ATOM 4158 C CZ . ARG B 1 96 ? -35.066 32.599 24.488 1.00 37.09 ? 69 ARG B CZ 1 ATOM 4159 N NH1 . ARG B 1 96 ? -34.395 32.018 25.465 1.00 39.21 ? 69 ARG B NH1 1 ATOM 4160 N NH2 . ARG B 1 96 ? -36.348 32.308 24.316 1.00 37.41 ? 69 ARG B NH2 1 ATOM 4161 N N . TRP B 1 97 ? -30.514 29.875 22.231 1.00 33.17 ? 70 TRP B N 1 ATOM 4162 C CA . TRP B 1 97 ? -29.598 29.075 23.035 1.00 29.90 ? 70 TRP B CA 1 ATOM 4163 C C . TRP B 1 97 ? -28.217 29.044 22.405 1.00 30.42 ? 70 TRP B C 1 ATOM 4164 O O . TRP B 1 97 ? -27.208 29.195 23.098 1.00 30.15 ? 70 TRP B O 1 ATOM 4165 C CB . TRP B 1 97 ? -30.103 27.660 23.210 1.00 27.40 ? 70 TRP B CB 1 ATOM 4166 C CG . TRP B 1 97 ? -31.351 27.565 23.961 1.00 25.73 ? 70 TRP B CG 1 ATOM 4167 C CD1 . TRP B 1 97 ? -31.954 28.533 24.676 1.00 27.18 ? 70 TRP B CD1 1 ATOM 4168 C CD2 . TRP B 1 97 ? -32.133 26.391 24.133 1.00 25.57 ? 70 TRP B CD2 1 ATOM 4169 N NE1 . TRP B 1 97 ? -33.091 28.046 25.261 1.00 26.87 ? 70 TRP B NE1 1 ATOM 4170 C CE2 . TRP B 1 97 ? -33.214 26.725 24.937 1.00 26.06 ? 70 TRP B CE2 1 ATOM 4171 C CE3 . TRP B 1 97 ? -32.019 25.081 23.669 1.00 25.40 ? 70 TRP B CE3 1 ATOM 4172 C CZ2 . TRP B 1 97 ? -34.182 25.804 25.295 1.00 26.75 ? 70 TRP B CZ2 1 ATOM 4173 C CZ3 . TRP B 1 97 ? -32.969 24.178 24.021 1.00 25.35 ? 70 TRP B CZ3 1 ATOM 4174 C CH2 . TRP B 1 97 ? -34.052 24.543 24.799 1.00 26.13 ? 70 TRP B CH2 1 ATOM 4175 N N . LEU B 1 98 ? -28.163 28.826 21.098 1.00 27.34 ? 71 LEU B N 1 ATOM 4176 C CA . LEU B 1 98 ? -26.895 28.767 20.421 1.00 28.97 ? 71 LEU B CA 1 ATOM 4177 C C . LEU B 1 98 ? -26.169 30.109 20.574 1.00 31.58 ? 71 LEU B C 1 ATOM 4178 O O . LEU B 1 98 ? -24.938 30.154 20.698 1.00 32.62 ? 71 LEU B O 1 ATOM 4179 C CB . LEU B 1 98 ? -27.098 28.435 18.939 1.00 30.17 ? 71 LEU B CB 1 ATOM 4180 C CG . LEU B 1 98 ? -25.889 28.478 18.003 1.00 31.70 ? 71 LEU B CG 1 ATOM 4181 C CD1 . LEU B 1 98 ? -26.047 27.488 16.856 1.00 33.24 ? 71 LEU B CD1 1 ATOM 4182 C CD2 . LEU B 1 98 ? -25.655 29.862 17.442 1.00 33.27 ? 71 LEU B CD2 1 ATOM 4183 N N . GLN B 1 99 ? -26.931 31.195 20.500 1.00 32.90 ? 72 GLN B N 1 ATOM 4184 C CA . GLN B 1 99 ? -26.365 32.532 20.648 1.00 34.04 ? 72 GLN B CA 1 ATOM 4185 C C . GLN B 1 99 ? -25.733 32.739 22.013 1.00 32.74 ? 72 GLN B C 1 ATOM 4186 O O . GLN B 1 99 ? -24.729 33.434 22.120 1.00 34.52 ? 72 GLN B O 1 ATOM 4187 C CB . GLN B 1 99 ? -27.433 33.604 20.402 1.00 33.22 ? 72 GLN B CB 1 ATOM 4188 C CG . GLN B 1 99 ? -27.825 33.749 18.942 1.00 35.15 ? 72 GLN B CG 1 ATOM 4189 C CD . GLN B 1 99 ? -26.890 34.659 18.156 1.00 37.67 ? 72 GLN B CD 1 ATOM 4190 O OE1 . GLN B 1 99 ? -27.295 35.745 17.695 1.00 42.32 ? 72 GLN B OE1 1 ATOM 4191 N NE2 . GLN B 1 99 ? -25.670 34.219 17.958 1.00 36.11 ? 72 GLN B NE2 1 ATOM 4192 N N . ALA B 1 100 ? -26.346 32.171 23.053 1.00 32.40 ? 73 ALA B N 1 ATOM 4193 C CA . ALA B 1 100 ? -25.820 32.285 24.407 1.00 32.36 ? 73 ALA B CA 1 ATOM 4194 C C . ALA B 1 100 ? -24.439 31.655 24.523 1.00 32.35 ? 73 ALA B C 1 ATOM 4195 O O . ALA B 1 100 ? -23.618 32.127 25.288 1.00 32.22 ? 73 ALA B O 1 ATOM 4196 C CB . ALA B 1 100 ? -26.779 31.685 25.412 1.00 33.33 ? 73 ALA B CB 1 ATOM 4197 N N . MET B 1 101 ? -24.179 30.603 23.746 1.00 31.78 ? 74 MET B N 1 ATOM 4198 C CA . MET B 1 101 ? -22.864 30.000 23.707 1.00 30.50 ? 74 MET B CA 1 ATOM 4199 C C . MET B 1 101 ? -21.854 30.912 23.008 1.00 34.36 ? 74 MET B C 1 ATOM 4200 O O . MET B 1 101 ? -20.752 31.126 23.520 1.00 31.12 ? 74 MET B O 1 ATOM 4201 C CB . MET B 1 101 ? -22.904 28.656 23.009 1.00 28.99 ? 74 MET B CB 1 ATOM 4202 C CG . MET B 1 101 ? -21.543 28.052 22.769 1.00 28.77 ? 74 MET B CG 1 ATOM 4203 S SD . MET B 1 101 ? -21.566 26.320 22.344 1.00 27.44 ? 74 MET B SD 1 ATOM 4204 C CE . MET B 1 101 ? -19.831 25.980 22.105 1.00 27.28 ? 74 MET B CE 1 ATOM 4205 N N . ILE B 1 102 ? -22.226 31.449 21.845 1.00 35.51 ? 75 ILE B N 1 ATOM 4206 C CA . ILE B 1 102 ? -21.345 32.368 21.115 1.00 36.06 ? 75 ILE B CA 1 ATOM 4207 C C . ILE B 1 102 ? -21.089 33.626 21.944 1.00 34.26 ? 75 ILE B C 1 ATOM 4208 O O . ILE B 1 102 ? -19.946 34.053 22.049 1.00 34.84 ? 75 ILE B O 1 ATOM 4209 C CB . ILE B 1 102 ? -21.895 32.738 19.724 1.00 39.86 ? 75 ILE B CB 1 ATOM 4210 C CG1 . ILE B 1 102 ? -21.890 31.505 18.817 1.00 38.58 ? 75 ILE B CG1 1 ATOM 4211 C CG2 . ILE B 1 102 ? -21.060 33.844 19.069 1.00 38.49 ? 75 ILE B CG2 1 ATOM 4212 C CD1 . ILE B 1 102 ? -22.676 31.694 17.534 1.00 39.22 ? 75 ILE B CD1 1 ATOM 4213 N N . PHE B 1 103 ? -22.128 34.164 22.577 1.00 32.88 ? 76 PHE B N 1 ATOM 4214 C CA . PHE B 1 103 ? -21.986 35.304 23.455 1.00 34.41 ? 76 PHE B CA 1 ATOM 4215 C C . PHE B 1 103 ? -20.985 35.039 24.581 1.00 39.20 ? 76 PHE B C 1 ATOM 4216 O O . PHE B 1 103 ? -20.101 35.855 24.836 1.00 38.73 ? 76 PHE B O 1 ATOM 4217 C CB . PHE B 1 103 ? -23.333 35.692 24.050 1.00 36.87 ? 76 PHE B CB 1 ATOM 4218 C CG . PHE B 1 103 ? -23.269 36.847 25.021 1.00 39.79 ? 76 PHE B CG 1 ATOM 4219 C CD1 . PHE B 1 103 ? -23.235 38.169 24.562 1.00 41.83 ? 76 PHE B CD1 1 ATOM 4220 C CD2 . PHE B 1 103 ? -23.227 36.623 26.394 1.00 42.96 ? 76 PHE B CD2 1 ATOM 4221 C CE1 . PHE B 1 103 ? -23.153 39.236 25.450 1.00 41.07 ? 76 PHE B CE1 1 ATOM 4222 C CE2 . PHE B 1 103 ? -23.153 37.687 27.296 1.00 42.91 ? 76 PHE B CE2 1 ATOM 4223 C CZ . PHE B 1 103 ? -23.119 38.995 26.823 1.00 45.78 ? 76 PHE B CZ 1 ATOM 4224 N N . ALA B 1 104 ? -21.133 33.903 25.257 1.00 36.86 ? 77 ALA B N 1 ATOM 4225 C CA . ALA B 1 104 ? -20.249 33.563 26.369 1.00 36.16 ? 77 ALA B CA 1 ATOM 4226 C C . ALA B 1 104 ? -18.813 33.473 25.915 1.00 35.28 ? 77 ALA B C 1 ATOM 4227 O O . ALA B 1 104 ? -17.919 33.922 26.630 1.00 34.02 ? 77 ALA B O 1 ATOM 4228 C CB . ALA B 1 104 ? -20.671 32.254 27.024 1.00 36.44 ? 77 ALA B CB 1 ATOM 4229 N N . ILE B 1 105 ? -18.591 32.915 24.727 1.00 32.75 ? 78 ILE B N 1 ATOM 4230 C CA . ILE B 1 105 ? -17.233 32.742 24.207 1.00 34.26 ? 78 ILE B CA 1 ATOM 4231 C C . ILE B 1 105 ? -16.589 34.085 23.817 1.00 40.21 ? 78 ILE B C 1 ATOM 4232 O O . ILE B 1 105 ? -15.391 34.299 24.060 1.00 41.63 ? 78 ILE B O 1 ATOM 4233 C CB . ILE B 1 105 ? -17.197 31.776 23.026 1.00 32.88 ? 78 ILE B CB 1 ATOM 4234 C CG1 . ILE B 1 105 ? -17.358 30.345 23.524 1.00 36.46 ? 78 ILE B CG1 1 ATOM 4235 C CG2 . ILE B 1 105 ? -15.904 31.878 22.237 1.00 32.67 ? 78 ILE B CG2 1 ATOM 4236 C CD1 . ILE B 1 105 ? -17.757 29.384 22.437 1.00 36.23 ? 78 ILE B CD1 1 ATOM 4237 N N . GLU B 1 106 ? -17.370 34.981 23.212 1.00 41.02 ? 79 GLU B N 1 ATOM 4238 C CA . GLU B 1 106 ? -16.866 36.307 22.845 1.00 40.45 ? 79 GLU B CA 1 ATOM 4239 C C . GLU B 1 106 ? -16.534 37.080 24.115 1.00 39.79 ? 79 GLU B C 1 ATOM 4240 O O . GLU B 1 106 ? -15.462 37.658 24.203 1.00 40.00 ? 79 GLU B O 1 ATOM 4241 C CB . GLU B 1 106 ? -17.879 37.071 21.989 1.00 38.53 ? 79 GLU B CB 1 ATOM 4242 C CG . GLU B 1 106 ? -18.004 36.474 20.589 1.00 42.57 ? 79 GLU B CG 1 ATOM 4243 C CD . GLU B 1 106 ? -18.941 37.261 19.679 1.00 46.32 ? 79 GLU B CD 1 ATOM 4244 O OE1 . GLU B 1 106 ? -19.526 38.274 20.151 1.00 49.83 ? 79 GLU B OE1 1 ATOM 4245 O OE2 . GLU B 1 106 ? -19.107 36.845 18.494 1.00 45.04 ? 79 GLU B OE2 1 ATOM 4246 N N . GLU B 1 107 ? -17.451 37.058 25.083 1.00 38.98 ? 80 GLU B N 1 ATOM 4247 C CA . GLU B 1 107 ? -17.252 37.688 26.393 1.00 40.27 ? 80 GLU B CA 1 ATOM 4248 C C . GLU B 1 107 ? -15.979 37.192 27.096 1.00 45.12 ? 80 GLU B C 1 ATOM 4249 O O . GLU B 1 107 ? -15.226 37.980 27.667 1.00 48.46 ? 80 GLU B O 1 ATOM 4250 C CB . GLU B 1 107 ? -18.437 37.409 27.296 1.00 39.90 ? 80 GLU B CB 1 ATOM 4251 C CG . GLU B 1 107 ? -18.441 38.166 28.608 1.00 41.66 ? 80 GLU B CG 1 ATOM 4252 C CD . GLU B 1 107 ? -19.722 37.937 29.386 1.00 45.76 ? 80 GLU B CD 1 ATOM 4253 O OE1 . GLU B 1 107 ? -19.859 36.867 30.004 1.00 50.16 ? 80 GLU B OE1 1 ATOM 4254 O OE2 . GLU B 1 107 ? -20.607 38.813 29.386 1.00 48.87 ? 80 GLU B OE2 1 ATOM 4255 N N . ILE B 1 108 ? -15.738 35.896 27.033 1.00 41.87 ? 81 ILE B N 1 ATOM 4256 C CA . ILE B 1 108 ? -14.553 35.325 27.629 1.00 43.52 ? 81 ILE B CA 1 ATOM 4257 C C . ILE B 1 108 ? -13.294 35.805 26.904 1.00 45.04 ? 81 ILE B C 1 ATOM 4258 O O . ILE B 1 108 ? -12.326 36.219 27.544 1.00 40.97 ? 81 ILE B O 1 ATOM 4259 C CB . ILE B 1 108 ? -14.624 33.786 27.632 1.00 39.66 ? 81 ILE B CB 1 ATOM 4260 C CG1 . ILE B 1 108 ? -15.640 33.333 28.687 1.00 39.76 ? 81 ILE B CG1 1 ATOM 4261 C CG2 . ILE B 1 108 ? -13.264 33.167 27.908 1.00 38.35 ? 81 ILE B CG2 1 ATOM 4262 C CD1 . ILE B 1 108 ? -16.174 31.929 28.448 1.00 39.58 ? 81 ILE B CD1 1 ATOM 4263 N N . ASN B 1 109 ? -13.314 35.735 25.581 1.00 41.72 ? 82 ASN B N 1 ATOM 4264 C CA . ASN B 1 109 ? -12.201 36.211 24.771 1.00 44.57 ? 82 ASN B CA 1 ATOM 4265 C C . ASN B 1 109 ? -11.932 37.715 24.962 1.00 49.11 ? 82 ASN B C 1 ATOM 4266 O O . ASN B 1 109 ? -10.795 38.157 24.838 1.00 52.33 ? 82 ASN B O 1 ATOM 4267 C CB . ASN B 1 109 ? -12.449 35.918 23.293 1.00 43.46 ? 82 ASN B CB 1 ATOM 4268 C CG . ASN B 1 109 ? -12.225 34.458 22.936 1.00 44.24 ? 82 ASN B CG 1 ATOM 4269 O OD1 . ASN B 1 109 ? -11.529 33.706 23.649 1.00 42.98 ? 82 ASN B OD1 1 ATOM 4270 N ND2 . ASN B 1 109 ? -12.814 34.040 21.819 1.00 39.20 ? 82 ASN B ND2 1 ATOM 4271 N N . SER B 1 110 ? -12.979 38.479 25.261 1.00 47.36 ? 83 SER B N 1 ATOM 4272 C CA . SER B 1 110 ? -12.859 39.900 25.575 1.00 53.65 ? 83 SER B CA 1 ATOM 4273 C C . SER B 1 110 ? -12.365 40.182 26.985 1.00 56.22 ? 83 SER B C 1 ATOM 4274 O O . SER B 1 110 ? -12.098 41.324 27.324 1.00 64.61 ? 83 SER B O 1 ATOM 4275 C CB . SER B 1 110 ? -14.208 40.603 25.394 1.00 50.21 ? 83 SER B CB 1 ATOM 4276 O OG . SER B 1 110 ? -14.484 40.722 24.012 1.00 56.18 ? 83 SER B OG 1 ATOM 4277 N N . SER B 1 111 ? -12.273 39.160 27.817 1.00 60.96 ? 84 SER B N 1 ATOM 4278 C CA . SER B 1 111 ? -11.866 39.359 29.191 1.00 64.02 ? 84 SER B CA 1 ATOM 4279 C C . SER B 1 111 ? -10.366 39.170 29.268 1.00 64.06 ? 84 SER B C 1 ATOM 4280 O O . SER B 1 111 ? -9.847 38.101 28.914 1.00 60.39 ? 84 SER B O 1 ATOM 4281 C CB . SER B 1 111 ? -12.578 38.384 30.127 1.00 66.64 ? 84 SER B CB 1 ATOM 4282 O OG . SER B 1 111 ? -12.215 38.634 31.473 1.00 70.22 ? 84 SER B OG 1 ATOM 4283 N N . PRO B 1 112 ? -9.658 40.210 29.722 1.00 68.63 ? 85 PRO B N 1 ATOM 4284 C CA . PRO B 1 112 ? -8.207 40.082 29.827 1.00 71.95 ? 85 PRO B CA 1 ATOM 4285 C C . PRO B 1 112 ? -7.818 39.079 30.912 1.00 68.65 ? 85 PRO B C 1 ATOM 4286 O O . PRO B 1 112 ? -6.883 38.302 30.721 1.00 72.63 ? 85 PRO B O 1 ATOM 4287 C CB . PRO B 1 112 ? -7.757 41.499 30.195 1.00 71.86 ? 85 PRO B CB 1 ATOM 4288 C CG . PRO B 1 112 ? -8.926 42.098 30.912 1.00 72.29 ? 85 PRO B CG 1 ATOM 4289 C CD . PRO B 1 112 ? -10.161 41.450 30.347 1.00 69.32 ? 85 PRO B CD 1 ATOM 4290 N N . ALA B 1 113 ? -8.569 39.085 32.014 1.00 67.89 ? 86 ALA B N 1 ATOM 4291 C CA . ALA B 1 113 ? -8.313 38.228 33.170 1.00 69.82 ? 86 ALA B CA 1 ATOM 4292 C C . ALA B 1 113 ? -8.387 36.738 32.830 1.00 68.34 ? 86 ALA B C 1 ATOM 4293 O O . ALA B 1 113 ? -7.471 35.969 33.113 1.00 72.91 ? 86 ALA B O 1 ATOM 4294 C CB . ALA B 1 113 ? -9.317 38.550 34.271 1.00 67.80 ? 86 ALA B CB 1 ATOM 4295 N N . LEU B 1 114 ? -9.496 36.349 32.219 1.00 63.30 ? 87 LEU B N 1 ATOM 4296 C CA . LEU B 1 114 ? -9.816 34.949 31.983 1.00 56.46 ? 87 LEU B CA 1 ATOM 4297 C C . LEU B 1 114 ? -9.152 34.448 30.708 1.00 52.92 ? 87 LEU B C 1 ATOM 4298 O O . LEU B 1 114 ? -9.457 34.935 29.625 1.00 57.84 ? 87 LEU B O 1 ATOM 4299 C CB . LEU B 1 114 ? -11.333 34.824 31.898 1.00 58.84 ? 87 LEU B CB 1 ATOM 4300 C CG . LEU B 1 114 ? -11.969 33.459 32.109 1.00 61.93 ? 87 LEU B CG 1 ATOM 4301 C CD1 . LEU B 1 114 ? -11.620 32.870 33.471 1.00 60.83 ? 87 LEU B CD1 1 ATOM 4302 C CD2 . LEU B 1 114 ? -13.473 33.618 31.955 1.00 63.48 ? 87 LEU B CD2 1 ATOM 4303 N N . LEU B 1 115 ? -8.233 33.494 30.844 1.00 48.22 ? 88 LEU B N 1 ATOM 4304 C CA . LEU B 1 115 ? -7.482 32.914 29.718 1.00 50.40 ? 88 LEU B CA 1 ATOM 4305 C C . LEU B 1 115 ? -6.780 33.990 28.861 1.00 57.99 ? 88 LEU B C 1 ATOM 4306 O O . LEU B 1 115 ? -7.100 34.167 27.674 1.00 54.39 ? 88 LEU B O 1 ATOM 4307 C CB . LEU B 1 115 ? -8.390 32.036 28.841 1.00 50.30 ? 88 LEU B CB 1 ATOM 4308 C CG . LEU B 1 115 ? -9.068 30.824 29.481 1.00 48.12 ? 88 LEU B CG 1 ATOM 4309 C CD1 . LEU B 1 115 ? -9.955 30.120 28.462 1.00 47.44 ? 88 LEU B CD1 1 ATOM 4310 C CD2 . LEU B 1 115 ? -8.043 29.845 30.037 1.00 48.31 ? 88 LEU B CD2 1 ATOM 4311 N N . PRO B 1 116 ? -5.804 34.695 29.458 1.00 67.29 ? 89 PRO B N 1 ATOM 4312 C CA . PRO B 1 116 ? -5.147 35.832 28.799 1.00 69.71 ? 89 PRO B CA 1 ATOM 4313 C C . PRO B 1 116 ? -4.342 35.455 27.555 1.00 66.00 ? 89 PRO B C 1 ATOM 4314 O O . PRO B 1 116 ? -4.428 36.145 26.542 1.00 67.83 ? 89 PRO B O 1 ATOM 4315 C CB . PRO B 1 116 ? -4.223 36.391 29.893 1.00 69.37 ? 89 PRO B CB 1 ATOM 4316 C CG . PRO B 1 116 ? -3.965 35.247 30.800 1.00 68.35 ? 89 PRO B CG 1 ATOM 4317 C CD . PRO B 1 116 ? -5.198 34.393 30.768 1.00 66.57 ? 89 PRO B CD 1 ATOM 4318 N N . ASN B 1 117 ? -3.578 34.375 27.615 1.00 62.21 ? 90 ASN B N 1 ATOM 4319 C CA . ASN B 1 117 ? -2.758 34.001 26.466 1.00 71.39 ? 90 ASN B CA 1 ATOM 4320 C C . ASN B 1 117 ? -3.567 33.618 25.208 1.00 73.36 ? 90 ASN B C 1 ATOM 4321 O O . ASN B 1 117 ? -3.080 33.768 24.085 1.00 69.59 ? 90 ASN B O 1 ATOM 4322 C CB . ASN B 1 117 ? -1.826 32.846 26.851 1.00 71.71 ? 90 ASN B CB 1 ATOM 4323 N N . LEU B 1 118 ? -4.803 33.144 25.409 1.00 75.16 ? 91 LEU B N 1 ATOM 4324 C CA . LEU B 1 118 ? -5.478 32.288 24.432 1.00 68.24 ? 91 LEU B CA 1 ATOM 4325 C C . LEU B 1 118 ? -6.856 32.761 23.963 1.00 57.57 ? 91 LEU B C 1 ATOM 4326 O O . LEU B 1 118 ? -7.541 33.535 24.635 1.00 50.58 ? 91 LEU B O 1 ATOM 4327 C CB . LEU B 1 118 ? -5.627 30.881 25.020 1.00 72.52 ? 91 LEU B CB 1 ATOM 4328 C CG . LEU B 1 118 ? -4.331 30.173 25.409 1.00 80.71 ? 91 LEU B CG 1 ATOM 4329 C CD1 . LEU B 1 118 ? -4.664 28.766 25.879 1.00 83.36 ? 91 LEU B CD1 1 ATOM 4330 C CD2 . LEU B 1 118 ? -3.323 30.129 24.265 1.00 82.55 ? 91 LEU B CD2 1 ATOM 4331 N N . THR B 1 119 ? -7.254 32.243 22.806 1.00 52.24 ? 92 THR B N 1 ATOM 4332 C CA . THR B 1 119 ? -8.602 32.437 22.284 1.00 48.04 ? 92 THR B CA 1 ATOM 4333 C C . THR B 1 119 ? -9.385 31.119 22.238 1.00 44.29 ? 92 THR B C 1 ATOM 4334 O O . THR B 1 119 ? -8.874 30.078 21.789 1.00 46.98 ? 92 THR B O 1 ATOM 4335 C CB . THR B 1 119 ? -8.566 32.968 20.850 1.00 48.38 ? 92 THR B CB 1 ATOM 4336 O OG1 . THR B 1 119 ? -7.852 32.031 20.036 1.00 51.44 ? 92 THR B OG1 1 ATOM 4337 C CG2 . THR B 1 119 ? -7.892 34.328 20.780 1.00 47.56 ? 92 THR B CG2 1 ATOM 4338 N N . LEU B 1 120 ? -10.622 31.168 22.710 1.00 42.39 ? 93 LEU B N 1 ATOM 4339 C CA . LEU B 1 120 ? -11.558 30.062 22.506 1.00 44.23 ? 93 LEU B CA 1 ATOM 4340 C C . LEU B 1 120 ? -12.262 30.233 21.174 1.00 39.79 ? 93 LEU B C 1 ATOM 4341 O O . LEU B 1 120 ? -12.884 31.282 20.918 1.00 37.83 ? 93 LEU B O 1 ATOM 4342 C CB . LEU B 1 120 ? -12.622 30.033 23.607 1.00 42.96 ? 93 LEU B CB 1 ATOM 4343 C CG . LEU B 1 120 ? -12.132 29.803 25.030 1.00 42.45 ? 93 LEU B CG 1 ATOM 4344 C CD1 . LEU B 1 120 ? -13.337 29.738 25.949 1.00 45.31 ? 93 LEU B CD1 1 ATOM 4345 C CD2 . LEU B 1 120 ? -11.303 28.532 25.146 1.00 42.97 ? 93 LEU B CD2 1 ATOM 4346 N N . GLY B 1 121 ? -12.176 29.208 20.345 1.00 37.39 ? 94 GLY B N 1 ATOM 4347 C CA . GLY B 1 121 ? -13.036 29.118 19.174 1.00 38.69 ? 94 GLY B CA 1 ATOM 4348 C C . GLY B 1 121 ? -14.191 28.136 19.372 1.00 40.00 ? 94 GLY B C 1 ATOM 4349 O O . GLY B 1 121 ? -14.401 27.590 20.453 1.00 35.03 ? 94 GLY B O 1 ATOM 4350 N N . TYR B 1 122 ? -14.932 27.880 18.301 1.00 40.16 ? 95 TYR B N 1 ATOM 4351 C CA . TYR B 1 122 ? -16.068 27.003 18.396 1.00 37.51 ? 95 TYR B CA 1 ATOM 4352 C C . TYR B 1 122 ? -16.448 26.358 17.071 1.00 39.76 ? 95 TYR B C 1 ATOM 4353 O O . TYR B 1 122 ? -16.087 26.837 15.985 1.00 34.95 ? 95 TYR B O 1 ATOM 4354 C CB . TYR B 1 122 ? -17.257 27.753 18.988 1.00 36.86 ? 95 TYR B CB 1 ATOM 4355 C CG . TYR B 1 122 ? -17.648 29.028 18.272 1.00 40.62 ? 95 TYR B CG 1 ATOM 4356 C CD1 . TYR B 1 122 ? -18.417 28.994 17.112 1.00 40.74 ? 95 TYR B CD1 1 ATOM 4357 C CD2 . TYR B 1 122 ? -17.289 30.281 18.777 1.00 42.17 ? 95 TYR B CD2 1 ATOM 4358 C CE1 . TYR B 1 122 ? -18.795 30.168 16.470 1.00 40.44 ? 95 TYR B CE1 1 ATOM 4359 C CE2 . TYR B 1 122 ? -17.664 31.457 18.143 1.00 42.02 ? 95 TYR B CE2 1 ATOM 4360 C CZ . TYR B 1 122 ? -18.413 31.390 16.981 1.00 41.37 ? 95 TYR B CZ 1 ATOM 4361 O OH . TYR B 1 122 ? -18.790 32.547 16.367 1.00 39.81 ? 95 TYR B OH 1 ATOM 4362 N N . ARG B 1 123 ? -17.194 25.267 17.201 1.00 34.79 ? 96 ARG B N 1 ATOM 4363 C CA . ARG B 1 123 ? -17.711 24.513 16.093 1.00 36.89 ? 96 ARG B CA 1 ATOM 4364 C C . ARG B 1 123 ? -19.083 23.985 16.530 1.00 35.66 ? 96 ARG B C 1 ATOM 4365 O O . ARG B 1 123 ? -19.174 23.004 17.280 1.00 33.18 ? 96 ARG B O 1 ATOM 4366 C CB . ARG B 1 123 ? -16.763 23.369 15.789 1.00 41.00 ? 96 ARG B CB 1 ATOM 4367 C CG . ARG B 1 123 ? -15.972 23.540 14.520 1.00 48.53 ? 96 ARG B CG 1 ATOM 4368 C CD . ARG B 1 123 ? -14.984 22.408 14.295 1.00 53.67 ? 96 ARG B CD 1 ATOM 4369 N NE . ARG B 1 123 ? -15.601 21.248 13.634 1.00 60.69 ? 96 ARG B NE 1 ATOM 4370 C CZ . ARG B 1 123 ? -15.330 19.963 13.889 1.00 63.69 ? 96 ARG B CZ 1 ATOM 4371 N NH1 . ARG B 1 123 ? -14.454 19.589 14.834 1.00 62.34 ? 96 ARG B NH1 1 ATOM 4372 N NH2 . ARG B 1 123 ? -15.964 19.029 13.194 1.00 65.03 ? 96 ARG B NH2 1 ATOM 4373 N N . ILE B 1 124 ? -20.141 24.635 16.050 1.00 33.12 ? 97 ILE B N 1 ATOM 4374 C CA . ILE B 1 124 ? -21.488 24.423 16.559 1.00 32.26 ? 97 ILE B CA 1 ATOM 4375 C C . ILE B 1 124 ? -22.398 23.922 15.442 1.00 32.48 ? 97 ILE B C 1 ATOM 4376 O O . ILE B 1 124 ? -22.469 24.549 14.383 1.00 28.60 ? 97 ILE B O 1 ATOM 4377 C CB . ILE B 1 124 ? -22.053 25.715 17.149 1.00 32.51 ? 97 ILE B CB 1 ATOM 4378 C CG1 . ILE B 1 124 ? -21.096 26.263 18.231 1.00 31.92 ? 97 ILE B CG1 1 ATOM 4379 C CG2 . ILE B 1 124 ? -23.455 25.476 17.715 1.00 34.72 ? 97 ILE B CG2 1 ATOM 4380 C CD1 . ILE B 1 124 ? -21.504 27.605 18.795 1.00 30.40 ? 97 ILE B CD1 1 ATOM 4381 N N . PHE B 1 125 ? -23.107 22.826 15.710 1.00 30.09 ? 98 PHE B N 1 ATOM 4382 C CA . PHE B 1 125 ? -23.975 22.160 14.733 1.00 32.03 ? 98 PHE B CA 1 ATOM 4383 C C . PHE B 1 125 ? -25.416 22.042 15.218 1.00 32.55 ? 98 PHE B C 1 ATOM 4384 O O . PHE B 1 125 ? -25.684 22.068 16.422 1.00 30.68 ? 98 PHE B O 1 ATOM 4385 C CB . PHE B 1 125 ? -23.476 20.768 14.449 1.00 32.42 ? 98 PHE B CB 1 ATOM 4386 C CG . PHE B 1 125 ? -22.122 20.733 13.822 1.00 35.59 ? 98 PHE B CG 1 ATOM 4387 C CD1 . PHE B 1 125 ? -21.963 21.013 12.473 1.00 39.54 ? 98 PHE B CD1 1 ATOM 4388 C CD2 . PHE B 1 125 ? -21.005 20.419 14.572 1.00 36.06 ? 98 PHE B CD2 1 ATOM 4389 C CE1 . PHE B 1 125 ? -20.700 20.984 11.883 1.00 41.64 ? 98 PHE B CE1 1 ATOM 4390 C CE2 . PHE B 1 125 ? -19.749 20.388 13.993 1.00 38.47 ? 98 PHE B CE2 1 ATOM 4391 C CZ . PHE B 1 125 ? -19.594 20.674 12.651 1.00 40.74 ? 98 PHE B CZ 1 ATOM 4392 N N . ASP B 1 126 ? -26.319 21.914 14.249 1.00 30.94 ? 99 ASP B N 1 ATOM 4393 C CA . ASP B 1 126 ? -27.753 21.739 14.453 1.00 30.00 ? 99 ASP B CA 1 ATOM 4394 C C . ASP B 1 126 ? -28.049 20.238 14.609 1.00 30.23 ? 99 ASP B C 1 ATOM 4395 O O . ASP B 1 126 ? -27.695 19.452 13.746 1.00 28.72 ? 99 ASP B O 1 ATOM 4396 C CB . ASP B 1 126 ? -28.489 22.289 13.203 1.00 30.85 ? 99 ASP B CB 1 ATOM 4397 C CG . ASP B 1 126 ? -30.011 22.233 13.304 1.00 31.48 ? 99 ASP B CG 1 ATOM 4398 O OD1 . ASP B 1 126 ? -30.584 21.814 14.338 1.00 31.92 ? 99 ASP B OD1 1 ATOM 4399 O OD2 . ASP B 1 126 ? -30.659 22.632 12.316 1.00 33.98 ? 99 ASP B OD2 1 ATOM 4400 N N . THR B 1 127 ? -28.715 19.848 15.694 1.00 29.69 ? 100 THR B N 1 ATOM 4401 C CA . THR B 1 127 ? -29.124 18.460 15.862 1.00 27.42 ? 100 THR B CA 1 ATOM 4402 C C . THR B 1 127 ? -30.485 18.140 15.236 1.00 29.93 ? 100 THR B C 1 ATOM 4403 O O . THR B 1 127 ? -30.819 16.956 15.053 1.00 29.78 ? 100 THR B O 1 ATOM 4404 C CB . THR B 1 127 ? -29.238 18.107 17.336 1.00 26.17 ? 100 THR B CB 1 ATOM 4405 O OG1 . THR B 1 127 ? -30.298 18.865 17.921 1.00 23.59 ? 100 THR B OG1 1 ATOM 4406 C CG2 . THR B 1 127 ? -27.922 18.386 18.055 1.00 26.56 ? 100 THR B CG2 1 ATOM 4407 N N . CYS B 1 128 ? -31.280 19.174 14.952 1.00 28.61 ? 101 CYS B N 1 ATOM 4408 C CA . CYS B 1 128 ? -32.679 19.000 14.550 1.00 32.28 ? 101 CYS B CA 1 ATOM 4409 C C . CYS B 1 128 ? -33.443 18.105 15.529 1.00 31.59 ? 101 CYS B C 1 ATOM 4410 O O . CYS B 1 128 ? -34.364 17.406 15.131 1.00 28.22 ? 101 CYS B O 1 ATOM 4411 C CB . CYS B 1 128 ? -32.785 18.452 13.110 1.00 35.40 ? 101 CYS B CB 1 ATOM 4412 S SG . CYS B 1 128 ? -31.752 19.465 12.057 1.00 43.55 ? 101 CYS B SG 1 ATOM 4413 N N . ASN B 1 129 ? -33.053 18.144 16.803 1.00 31.80 ? 102 ASN B N 1 ATOM 4414 C CA . ASN B 1 129 ? -33.608 17.259 17.820 1.00 34.66 ? 102 ASN B CA 1 ATOM 4415 C C . ASN B 1 129 ? -33.584 15.793 17.477 1.00 30.79 ? 102 ASN B C 1 ATOM 4416 O O . ASN B 1 129 ? -34.463 15.079 17.900 1.00 30.62 ? 102 ASN B O 1 ATOM 4417 C CB . ASN B 1 129 ? -35.067 17.607 18.102 1.00 40.06 ? 102 ASN B CB 1 ATOM 4418 C CG . ASN B 1 129 ? -35.219 18.586 19.211 1.00 46.27 ? 102 ASN B CG 1 ATOM 4419 O OD1 . ASN B 1 129 ? -34.419 18.628 20.162 1.00 55.09 ? 102 ASN B OD1 1 ATOM 4420 N ND2 . ASN B 1 129 ? -36.252 19.390 19.115 1.00 54.10 ? 102 ASN B ND2 1 ATOM 4421 N N . THR B 1 130 ? -32.602 15.351 16.708 1.00 29.10 ? 103 THR B N 1 ATOM 4422 C CA . THR B 1 130 ? -32.603 14.002 16.188 1.00 31.87 ? 103 THR B CA 1 ATOM 4423 C C . THR B 1 130 ? -31.253 13.374 16.487 1.00 32.11 ? 103 THR B C 1 ATOM 4424 O O . THR B 1 130 ? -30.190 14.035 16.373 1.00 29.48 ? 103 THR B O 1 ATOM 4425 C CB . THR B 1 130 ? -32.881 14.009 14.647 1.00 35.03 ? 103 THR B CB 1 ATOM 4426 O OG1 . THR B 1 130 ? -34.105 14.704 14.402 1.00 40.01 ? 103 THR B OG1 1 ATOM 4427 C CG2 . THR B 1 130 ? -33.032 12.629 14.061 1.00 36.47 ? 103 THR B CG2 1 ATOM 4428 N N . VAL B 1 131 ? -31.300 12.098 16.866 1.00 28.10 ? 104 VAL B N 1 ATOM 4429 C CA . VAL B 1 131 ? -30.080 11.362 17.136 1.00 29.03 ? 104 VAL B CA 1 ATOM 4430 C C . VAL B 1 131 ? -29.150 11.343 15.911 1.00 29.14 ? 104 VAL B C 1 ATOM 4431 O O . VAL B 1 131 ? -27.943 11.529 16.047 1.00 29.01 ? 104 VAL B O 1 ATOM 4432 C CB . VAL B 1 131 ? -30.382 9.934 17.621 1.00 27.39 ? 104 VAL B CB 1 ATOM 4433 C CG1 . VAL B 1 131 ? -29.132 9.058 17.572 1.00 27.30 ? 104 VAL B CG1 1 ATOM 4434 C CG2 . VAL B 1 131 ? -30.911 9.969 19.044 1.00 27.79 ? 104 VAL B CG2 1 ATOM 4435 N N . SER B 1 132 ? -29.698 11.107 14.718 1.00 30.23 ? 105 SER B N 1 ATOM 4436 C CA . SER B 1 132 ? -28.842 10.863 13.541 1.00 31.38 ? 105 SER B CA 1 ATOM 4437 C C . SER B 1 132 ? -28.014 12.101 13.177 1.00 30.07 ? 105 SER B C 1 ATOM 4438 O O . SER B 1 132 ? -26.810 12.007 12.934 1.00 31.99 ? 105 SER B O 1 ATOM 4439 C CB . SER B 1 132 ? -29.683 10.405 12.342 1.00 31.12 ? 105 SER B CB 1 ATOM 4440 O OG . SER B 1 132 ? -30.618 11.412 12.024 1.00 32.54 ? 105 SER B OG 1 ATOM 4441 N N . LYS B 1 133 ? -28.643 13.259 13.163 1.00 29.72 ? 106 LYS B N 1 ATOM 4442 C CA . LYS B 1 133 ? -27.901 14.494 12.916 1.00 31.47 ? 106 LYS B CA 1 ATOM 4443 C C . LYS B 1 133 ? -26.878 14.783 14.016 1.00 30.44 ? 106 LYS B C 1 ATOM 4444 O O . LYS B 1 133 ? -25.746 15.181 13.731 1.00 31.82 ? 106 LYS B O 1 ATOM 4445 C CB . LYS B 1 133 ? -28.841 15.682 12.824 1.00 33.61 ? 106 LYS B CB 1 ATOM 4446 C CG . LYS B 1 133 ? -29.870 15.588 11.728 1.00 38.19 ? 106 LYS B CG 1 ATOM 4447 C CD . LYS B 1 133 ? -29.271 15.829 10.362 1.00 44.19 ? 106 LYS B CD 1 ATOM 4448 C CE . LYS B 1 133 ? -30.331 15.641 9.283 1.00 47.23 ? 106 LYS B CE 1 ATOM 4449 N NZ . LYS B 1 133 ? -29.798 15.994 7.945 1.00 50.66 ? 106 LYS B NZ 1 ATOM 4450 N N . ALA B 1 134 ? -27.283 14.622 15.272 1.00 26.69 ? 107 ALA B N 1 ATOM 4451 C CA . ALA B 1 134 ? -26.363 14.845 16.384 1.00 26.15 ? 107 ALA B CA 1 ATOM 4452 C C . ALA B 1 134 ? -25.133 13.977 16.252 1.00 27.25 ? 107 ALA B C 1 ATOM 4453 O O . ALA B 1 134 ? -24.004 14.431 16.505 1.00 28.99 ? 107 ALA B O 1 ATOM 4454 C CB . ALA B 1 134 ? -27.039 14.591 17.712 1.00 26.36 ? 107 ALA B CB 1 ATOM 4455 N N . LEU B 1 135 ? -25.341 12.734 15.849 1.00 28.27 ? 108 LEU B N 1 ATOM 4456 C CA . LEU B 1 135 ? -24.234 11.802 15.718 1.00 31.80 ? 108 LEU B CA 1 ATOM 4457 C C . LEU B 1 135 ? -23.280 12.095 14.540 1.00 32.53 ? 108 LEU B C 1 ATOM 4458 O O . LEU B 1 135 ? -22.088 11.848 14.649 1.00 33.33 ? 108 LEU B O 1 ATOM 4459 C CB . LEU B 1 135 ? -24.758 10.371 15.605 1.00 32.93 ? 108 LEU B CB 1 ATOM 4460 C CG . LEU B 1 135 ? -25.006 9.595 16.879 1.00 36.19 ? 108 LEU B CG 1 ATOM 4461 C CD1 . LEU B 1 135 ? -25.329 8.151 16.518 1.00 37.36 ? 108 LEU B CD1 1 ATOM 4462 C CD2 . LEU B 1 135 ? -23.867 9.657 17.887 1.00 34.64 ? 108 LEU B CD2 1 ATOM 4463 N N . GLU B 1 136 ? -23.812 12.541 13.410 1.00 33.52 ? 109 GLU B N 1 ATOM 4464 C CA . GLU B 1 136 ? -22.974 13.016 12.299 1.00 37.66 ? 109 GLU B CA 1 ATOM 4465 C C . GLU B 1 136 ? -22.059 14.129 12.787 1.00 34.84 ? 109 GLU B C 1 ATOM 4466 O O . GLU B 1 136 ? -20.856 14.103 12.534 1.00 31.19 ? 109 GLU B O 1 ATOM 4467 C CB . GLU B 1 136 ? -23.819 13.569 11.148 1.00 41.38 ? 109 GLU B CB 1 ATOM 4468 C CG . GLU B 1 136 ? -24.628 12.533 10.400 1.00 46.04 ? 109 GLU B CG 1 ATOM 4469 C CD . GLU B 1 136 ? -25.567 13.150 9.354 1.00 55.10 ? 109 GLU B CD 1 ATOM 4470 O OE1 . GLU B 1 136 ? -25.494 14.384 9.092 1.00 56.11 ? 109 GLU B OE1 1 ATOM 4471 O OE2 . GLU B 1 136 ? -26.378 12.381 8.788 1.00 61.57 ? 109 GLU B OE2 1 ATOM 4472 N N . ALA B 1 137 ? -22.642 15.094 13.492 1.00 33.78 ? 110 ALA B N 1 ATOM 4473 C CA . ALA B 1 137 ? -21.879 16.208 14.067 1.00 33.13 ? 110 ALA B CA 1 ATOM 4474 C C . ALA B 1 137 ? -20.816 15.693 15.005 1.00 33.06 ? 110 ALA B C 1 ATOM 4475 O O . ALA B 1 137 ? -19.658 16.094 14.930 1.00 33.80 ? 110 ALA B O 1 ATOM 4476 C CB . ALA B 1 137 ? -22.796 17.151 14.811 1.00 34.72 ? 110 ALA B CB 1 ATOM 4477 N N . THR B 1 138 ? -21.200 14.762 15.864 1.00 29.86 ? 111 THR B N 1 ATOM 4478 C CA . THR B 1 138 ? -20.288 14.242 16.842 1.00 30.95 ? 111 THR B CA 1 ATOM 4479 C C . THR B 1 138 ? -19.114 13.468 16.224 1.00 32.73 ? 111 THR B C 1 ATOM 4480 O O . THR B 1 138 ? -17.984 13.522 16.738 1.00 32.25 ? 111 THR B O 1 ATOM 4481 C CB . THR B 1 138 ? -21.046 13.379 17.871 1.00 29.50 ? 111 THR B CB 1 ATOM 4482 O OG1 . THR B 1 138 ? -22.057 14.203 18.489 1.00 31.36 ? 111 THR B OG1 1 ATOM 4483 C CG2 . THR B 1 138 ? -20.091 12.859 18.941 1.00 29.44 ? 111 THR B CG2 1 ATOM 4484 N N . LEU B 1 139 ? -19.367 12.747 15.135 1.00 34.14 ? 112 LEU B N 1 ATOM 4485 C CA . LEU B 1 139 ? -18.269 12.086 14.403 1.00 35.36 ? 112 LEU B CA 1 ATOM 4486 C C . LEU B 1 139 ? -17.229 13.106 13.911 1.00 35.78 ? 112 LEU B C 1 ATOM 4487 O O . LEU B 1 139 ? -16.039 12.831 13.898 1.00 36.99 ? 112 LEU B O 1 ATOM 4488 C CB . LEU B 1 139 ? -18.808 11.256 13.241 1.00 35.70 ? 112 LEU B CB 1 ATOM 4489 C CG . LEU B 1 139 ? -19.537 9.984 13.641 1.00 36.24 ? 112 LEU B CG 1 ATOM 4490 C CD1 . LEU B 1 139 ? -20.292 9.422 12.451 1.00 38.83 ? 112 LEU B CD1 1 ATOM 4491 C CD2 . LEU B 1 139 ? -18.580 8.938 14.175 1.00 34.77 ? 112 LEU B CD2 1 ATOM 4492 N N . SER B 1 140 ? -17.677 14.297 13.541 1.00 37.88 ? 113 SER B N 1 ATOM 4493 C CA . SER B 1 140 ? -16.753 15.356 13.182 1.00 40.11 ? 113 SER B CA 1 ATOM 4494 C C . SER B 1 140 ? -15.979 15.867 14.426 1.00 42.25 ? 113 SER B C 1 ATOM 4495 O O . SER B 1 140 ? -14.789 16.107 14.333 1.00 43.49 ? 113 SER B O 1 ATOM 4496 C CB . SER B 1 140 ? -17.471 16.450 12.382 1.00 41.21 ? 113 SER B CB 1 ATOM 4497 O OG . SER B 1 140 ? -17.898 17.518 13.188 1.00 47.18 ? 113 SER B OG 1 ATOM 4498 N N . PHE B 1 141 ? -16.620 15.994 15.591 1.00 39.47 ? 114 PHE B N 1 ATOM 4499 C CA . PHE B 1 141 ? -15.892 16.394 16.806 1.00 37.48 ? 114 PHE B CA 1 ATOM 4500 C C . PHE B 1 141 ? -14.778 15.421 17.172 1.00 38.68 ? 114 PHE B C 1 ATOM 4501 O O . PHE B 1 141 ? -13.799 15.831 17.752 1.00 42.55 ? 114 PHE B O 1 ATOM 4502 C CB . PHE B 1 141 ? -16.788 16.473 18.048 1.00 34.30 ? 114 PHE B CB 1 ATOM 4503 C CG . PHE B 1 141 ? -17.861 17.503 17.980 1.00 33.95 ? 114 PHE B CG 1 ATOM 4504 C CD1 . PHE B 1 141 ? -17.661 18.706 17.341 1.00 33.22 ? 114 PHE B CD1 1 ATOM 4505 C CD2 . PHE B 1 141 ? -19.084 17.267 18.601 1.00 30.05 ? 114 PHE B CD2 1 ATOM 4506 C CE1 . PHE B 1 141 ? -18.667 19.642 17.282 1.00 32.82 ? 114 PHE B CE1 1 ATOM 4507 C CE2 . PHE B 1 141 ? -20.078 18.219 18.572 1.00 29.45 ? 114 PHE B CE2 1 ATOM 4508 C CZ . PHE B 1 141 ? -19.867 19.406 17.910 1.00 32.94 ? 114 PHE B CZ 1 ATOM 4509 N N . VAL B 1 142 ? -14.961 14.134 16.909 1.00 40.24 ? 115 VAL B N 1 ATOM 4510 C CA . VAL B 1 142 ? -13.978 13.147 17.318 1.00 39.89 ? 115 VAL B CA 1 ATOM 4511 C C . VAL B 1 142 ? -13.080 12.703 16.164 1.00 41.73 ? 115 VAL B C 1 ATOM 4512 O O . VAL B 1 142 ? -12.335 11.741 16.312 1.00 44.06 ? 115 VAL B O 1 ATOM 4513 C CB . VAL B 1 142 ? -14.628 11.903 17.966 1.00 38.70 ? 115 VAL B CB 1 ATOM 4514 C CG1 . VAL B 1 142 ? -15.511 12.318 19.141 1.00 41.55 ? 115 VAL B CG1 1 ATOM 4515 C CG2 . VAL B 1 142 ? -15.414 11.091 16.955 1.00 39.09 ? 115 VAL B CG2 1 ATOM 4516 N N . ALA B 1 143 ? -13.142 13.396 15.033 1.00 44.83 ? 116 ALA B N 1 ATOM 4517 C CA . ALA B 1 143 ? -12.446 12.959 13.818 1.00 48.89 ? 116 ALA B CA 1 ATOM 4518 C C . ALA B 1 143 ? -10.970 12.649 14.061 1.00 53.99 ? 116 ALA B C 1 ATOM 4519 O O . ALA B 1 143 ? -10.490 11.595 13.654 1.00 55.82 ? 116 ALA B O 1 ATOM 4520 C CB . ALA B 1 143 ? -12.591 14.005 12.730 1.00 49.97 ? 116 ALA B CB 1 ATOM 4521 N N . GLN B 1 144 ? -10.273 13.541 14.761 1.00 59.45 ? 117 GLN B N 1 ATOM 4522 C CA . GLN B 1 144 ? -8.849 13.349 15.092 1.00 67.94 ? 117 GLN B CA 1 ATOM 4523 C C . GLN B 1 144 ? -8.649 12.104 15.983 1.00 68.99 ? 117 GLN B C 1 ATOM 4524 O O . GLN B 1 144 ? -7.960 11.149 15.600 1.00 70.49 ? 117 GLN B O 1 ATOM 4525 C CB . GLN B 1 144 ? -8.309 14.620 15.777 1.00 70.98 ? 117 GLN B CB 1 ATOM 4526 C CG . GLN B 1 144 ? -6.796 14.842 15.776 1.00 81.84 ? 117 GLN B CG 1 ATOM 4527 C CD . GLN B 1 144 ? -5.976 13.578 15.967 1.00 84.01 ? 117 GLN B CD 1 ATOM 4528 O OE1 . GLN B 1 144 ? -5.831 13.108 17.086 1.00 88.56 ? 117 GLN B OE1 1 ATOM 4529 N NE2 . GLN B 1 144 ? -5.435 13.021 14.876 1.00 82.89 ? 117 GLN B NE2 1 ATOM 4530 N N . ASN B 1 145 ? -9.277 12.124 17.156 1.00 69.02 ? 118 ASN B N 1 ATOM 4531 C CA . ASN B 1 145 ? -9.237 11.015 18.128 1.00 69.05 ? 118 ASN B CA 1 ATOM 4532 C C . ASN B 1 145 ? -9.501 9.646 17.500 1.00 73.23 ? 118 ASN B C 1 ATOM 4533 O O . ASN B 1 145 ? -8.836 8.670 17.834 1.00 74.10 ? 118 ASN B O 1 ATOM 4534 C CB . ASN B 1 145 ? -10.290 11.199 19.240 1.00 68.28 ? 118 ASN B CB 1 ATOM 4535 C CG . ASN B 1 145 ? -10.254 12.570 19.887 1.00 61.60 ? 118 ASN B CG 1 ATOM 4536 O OD1 . ASN B 1 145 ? -9.680 12.742 20.957 1.00 65.92 ? 118 ASN B OD1 1 ATOM 4537 N ND2 . ASN B 1 145 ? -10.884 13.548 19.249 1.00 61.11 ? 118 ASN B ND2 1 ATOM 4538 N N . LYS B 1 146 ? -10.502 9.587 16.615 1.00 83.07 ? 119 LYS B N 1 ATOM 4539 C CA . LYS B 1 146 ? -10.928 8.338 15.964 1.00 84.51 ? 119 LYS B CA 1 ATOM 4540 C C . LYS B 1 146 ? -9.828 7.767 15.066 1.00 89.64 ? 119 LYS B C 1 ATOM 4541 O O . LYS B 1 146 ? -9.570 6.560 15.094 1.00 89.44 ? 119 LYS B O 1 ATOM 4542 C CB . LYS B 1 146 ? -12.195 8.552 15.127 1.00 82.88 ? 119 LYS B CB 1 ATOM 4543 C CG . LYS B 1 146 ? -12.754 7.256 14.551 1.00 85.20 ? 119 LYS B CG 1 ATOM 4544 C CD . LYS B 1 146 ? -13.486 7.464 13.236 1.00 87.19 ? 119 LYS B CD 1 ATOM 4545 C CE . LYS B 1 146 ? -13.423 6.247 12.302 1.00 89.74 ? 119 LYS B CE 1 ATOM 4546 N NZ . LYS B 1 146 ? -14.630 5.363 12.275 1.00 88.94 ? 119 LYS B NZ 1 ATOM 4547 N N . ILE B 1 147 ? -9.194 8.637 14.276 1.00 88.67 ? 120 ILE B N 1 ATOM 4548 C CA . ILE B 1 147 ? -8.037 8.260 13.460 1.00 86.94 ? 120 ILE B CA 1 ATOM 4549 C C . ILE B 1 147 ? -6.983 7.542 14.312 1.00 89.65 ? 120 ILE B C 1 ATOM 4550 O O . ILE B 1 147 ? -6.321 6.628 13.828 1.00 95.64 ? 120 ILE B O 1 ATOM 4551 C CB . ILE B 1 147 ? -7.400 9.478 12.766 1.00 83.22 ? 120 ILE B CB 1 ATOM 4552 N N . ASP B 1 148 ? -6.846 7.944 15.579 1.00 88.03 ? 121 ASP B N 1 ATOM 4553 C CA . ASP B 1 148 ? -6.065 7.175 16.563 1.00 85.69 ? 121 ASP B CA 1 ATOM 4554 C C . ASP B 1 148 ? -6.767 5.869 16.928 1.00 81.76 ? 121 ASP B C 1 ATOM 4555 O O . ASP B 1 148 ? -6.680 4.891 16.186 1.00 85.29 ? 121 ASP B O 1 ATOM 4556 C CB . ASP B 1 148 ? -5.793 7.985 17.843 1.00 84.49 ? 121 ASP B CB 1 ATOM 4557 C CG . ASP B 1 148 ? -5.194 9.345 17.559 1.00 82.72 ? 121 ASP B CG 1 ATOM 4558 O OD1 . ASP B 1 148 ? -4.642 9.534 16.453 1.00 81.84 ? 121 ASP B OD1 1 ATOM 4559 O OD2 . ASP B 1 148 ? -5.282 10.224 18.440 1.00 80.55 ? 121 ASP B OD2 1 ATOM 4560 N N . SER B 1 164 ? -9.394 19.907 16.359 1.00 59.99 ? 137 SER B N 1 ATOM 4561 C CA . SER B 1 164 ? -9.436 19.173 17.639 1.00 57.96 ? 137 SER B CA 1 ATOM 4562 C C . SER B 1 164 ? -10.392 19.764 18.694 1.00 51.84 ? 137 SER B C 1 ATOM 4563 O O . SER B 1 164 ? -10.190 20.877 19.176 1.00 50.21 ? 137 SER B O 1 ATOM 4564 C CB . SER B 1 164 ? -8.038 19.078 18.223 1.00 59.79 ? 137 SER B CB 1 ATOM 4565 O OG . SER B 1 164 ? -8.001 18.043 19.191 1.00 59.66 ? 137 SER B OG 1 ATOM 4566 N N . THR B 1 165 ? -11.420 18.996 19.066 1.00 47.99 ? 138 THR B N 1 ATOM 4567 C CA . THR B 1 165 ? -12.476 19.472 19.966 1.00 42.50 ? 138 THR B CA 1 ATOM 4568 C C . THR B 1 165 ? -12.159 19.066 21.375 1.00 35.79 ? 138 THR B C 1 ATOM 4569 O O . THR B 1 165 ? -11.927 17.905 21.644 1.00 40.98 ? 138 THR B O 1 ATOM 4570 C CB . THR B 1 165 ? -13.836 18.874 19.582 1.00 45.89 ? 138 THR B CB 1 ATOM 4571 O OG1 . THR B 1 165 ? -14.031 19.034 18.178 1.00 48.29 ? 138 THR B OG1 1 ATOM 4572 C CG2 . THR B 1 165 ? -14.949 19.570 20.324 1.00 45.11 ? 138 THR B CG2 1 ATOM 4573 N N . ILE B 1 166 ? -12.148 20.024 22.280 1.00 33.67 ? 139 ILE B N 1 ATOM 4574 C CA . ILE B 1 166 ? -11.712 19.778 23.656 1.00 36.16 ? 139 ILE B CA 1 ATOM 4575 C C . ILE B 1 166 ? -12.866 19.560 24.639 1.00 33.18 ? 139 ILE B C 1 ATOM 4576 O O . ILE B 1 166 ? -12.667 19.012 25.701 1.00 33.34 ? 139 ILE B O 1 ATOM 4577 C CB . ILE B 1 166 ? -10.805 20.937 24.146 1.00 36.94 ? 139 ILE B CB 1 ATOM 4578 C CG1 . ILE B 1 166 ? -9.626 20.364 24.878 1.00 41.74 ? 139 ILE B CG1 1 ATOM 4579 C CG2 . ILE B 1 166 ? -11.538 21.973 24.991 1.00 38.87 ? 139 ILE B CG2 1 ATOM 4580 C CD1 . ILE B 1 166 ? -8.665 19.694 23.920 1.00 44.75 ? 139 ILE B CD1 1 ATOM 4581 N N . ALA B 1 167 ? -14.050 20.028 24.281 1.00 31.07 ? 140 ALA B N 1 ATOM 4582 C CA . ALA B 1 167 ? -15.241 19.851 25.087 1.00 29.70 ? 140 ALA B CA 1 ATOM 4583 C C . ALA B 1 167 ? -16.462 20.171 24.215 1.00 30.33 ? 140 ALA B C 1 ATOM 4584 O O . ALA B 1 167 ? -16.333 20.886 23.219 1.00 29.63 ? 140 ALA B O 1 ATOM 4585 C CB . ALA B 1 167 ? -15.201 20.769 26.289 1.00 28.02 ? 140 ALA B CB 1 ATOM 4586 N N . VAL B 1 168 ? -17.625 19.627 24.592 1.00 27.27 ? 141 VAL B N 1 ATOM 4587 C CA . VAL B 1 168 ? -18.849 19.809 23.833 1.00 27.32 ? 141 VAL B CA 1 ATOM 4588 C C . VAL B 1 168 ? -19.937 20.297 24.751 1.00 26.59 ? 141 VAL B C 1 ATOM 4589 O O . VAL B 1 168 ? -20.081 19.796 25.860 1.00 28.22 ? 141 VAL B O 1 ATOM 4590 C CB . VAL B 1 168 ? -19.268 18.509 23.132 1.00 27.17 ? 141 VAL B CB 1 ATOM 4591 C CG1 . VAL B 1 168 ? -20.621 18.671 22.450 1.00 28.47 ? 141 VAL B CG1 1 ATOM 4592 C CG2 . VAL B 1 168 ? -18.214 18.125 22.097 1.00 27.34 ? 141 VAL B CG2 1 ATOM 4593 N N . VAL B 1 169 ? -20.647 21.327 24.300 1.00 25.56 ? 142 VAL B N 1 ATOM 4594 C CA . VAL B 1 169 ? -21.797 21.872 24.979 1.00 25.49 ? 142 VAL B CA 1 ATOM 4595 C C . VAL B 1 169 ? -23.036 21.321 24.288 1.00 27.51 ? 142 VAL B C 1 ATOM 4596 O O . VAL B 1 169 ? -23.239 21.569 23.095 1.00 27.06 ? 142 VAL B O 1 ATOM 4597 C CB . VAL B 1 169 ? -21.781 23.414 24.907 1.00 26.88 ? 142 VAL B CB 1 ATOM 4598 C CG1 . VAL B 1 169 ? -23.065 24.002 25.458 1.00 25.69 ? 142 VAL B CG1 1 ATOM 4599 C CG2 . VAL B 1 169 ? -20.588 23.953 25.687 1.00 27.25 ? 142 VAL B CG2 1 ATOM 4600 N N . GLY B 1 170 ? -23.850 20.559 25.025 1.00 26.98 ? 143 GLY B N 1 ATOM 4601 C CA . GLY B 1 170 ? -25.058 19.943 24.463 1.00 27.87 ? 143 GLY B CA 1 ATOM 4602 C C . GLY B 1 170 ? -25.235 18.504 24.913 1.00 26.44 ? 143 GLY B C 1 ATOM 4603 O O . GLY B 1 170 ? -24.460 18.028 25.745 1.00 26.60 ? 143 GLY B O 1 ATOM 4604 N N . ALA B 1 171 ? -26.260 17.810 24.415 1.00 24.32 ? 144 ALA B N 1 ATOM 4605 C CA . ALA B 1 171 ? -27.303 18.351 23.541 1.00 25.37 ? 144 ALA B CA 1 ATOM 4606 C C . ALA B 1 171 ? -28.549 18.689 24.391 1.00 25.26 ? 144 ALA B C 1 ATOM 4607 O O . ALA B 1 171 ? -28.457 18.798 25.610 1.00 25.80 ? 144 ALA B O 1 ATOM 4608 C CB . ALA B 1 171 ? -27.644 17.316 22.485 1.00 23.74 ? 144 ALA B CB 1 ATOM 4609 N N . THR B 1 172 ? -29.714 18.822 23.763 1.00 23.75 ? 145 THR B N 1 ATOM 4610 C CA . THR B 1 172 ? -30.937 19.152 24.484 1.00 24.63 ? 145 THR B CA 1 ATOM 4611 C C . THR B 1 172 ? -31.726 17.928 24.978 1.00 26.22 ? 145 THR B C 1 ATOM 4612 O O . THR B 1 172 ? -31.828 17.703 26.183 1.00 27.19 ? 145 THR B O 1 ATOM 4613 C CB . THR B 1 172 ? -31.843 20.037 23.617 1.00 24.91 ? 145 THR B CB 1 ATOM 4614 O OG1 . THR B 1 172 ? -31.148 21.256 23.345 1.00 26.71 ? 145 THR B OG1 1 ATOM 4615 C CG2 . THR B 1 172 ? -33.175 20.363 24.338 1.00 24.32 ? 145 THR B CG2 1 ATOM 4616 N N . GLY B 1 173 ? -32.319 17.165 24.061 1.00 24.76 ? 146 GLY B N 1 ATOM 4617 C CA . GLY B 1 173 ? -33.083 15.986 24.436 1.00 24.62 ? 146 GLY B CA 1 ATOM 4618 C C . GLY B 1 173 ? -32.186 14.891 25.037 1.00 24.77 ? 146 GLY B C 1 ATOM 4619 O O . GLY B 1 173 ? -31.088 14.634 24.523 1.00 24.13 ? 146 GLY B O 1 ATOM 4620 N N . SER B 1 174 ? -32.655 14.228 26.099 1.00 23.54 ? 147 SER B N 1 ATOM 4621 C CA . SER B 1 174 ? -31.841 13.198 26.777 1.00 23.72 ? 147 SER B CA 1 ATOM 4622 C C . SER B 1 174 ? -31.484 12.047 25.877 1.00 23.75 ? 147 SER B C 1 ATOM 4623 O O . SER B 1 174 ? -30.390 11.515 25.987 1.00 22.27 ? 147 SER B O 1 ATOM 4624 C CB . SER B 1 174 ? -32.523 12.663 28.030 1.00 23.61 ? 147 SER B CB 1 ATOM 4625 O OG . SER B 1 174 ? -32.440 13.613 29.052 1.00 24.02 ? 147 SER B OG 1 ATOM 4626 N N . GLY B 1 175 ? -32.373 11.685 24.955 1.00 24.74 ? 148 GLY B N 1 ATOM 4627 C CA . GLY B 1 175 ? -32.050 10.646 23.979 1.00 24.73 ? 148 GLY B CA 1 ATOM 4628 C C . GLY B 1 175 ? -30.918 11.028 23.031 1.00 25.03 ? 148 GLY B C 1 ATOM 4629 O O . GLY B 1 175 ? -30.079 10.199 22.694 1.00 26.36 ? 148 GLY B O 1 ATOM 4630 N N . VAL B 1 176 ? -30.900 12.291 22.594 1.00 24.64 ? 149 VAL B N 1 ATOM 4631 C CA . VAL B 1 176 ? -29.804 12.816 21.768 1.00 23.69 ? 149 VAL B CA 1 ATOM 4632 C C . VAL B 1 176 ? -28.503 12.879 22.587 1.00 24.29 ? 149 VAL B C 1 ATOM 4633 O O . VAL B 1 176 ? -27.447 12.417 22.126 1.00 23.71 ? 149 VAL B O 1 ATOM 4634 C CB . VAL B 1 176 ? -30.163 14.198 21.182 1.00 24.37 ? 149 VAL B CB 1 ATOM 4635 C CG1 . VAL B 1 176 ? -29.002 14.785 20.394 1.00 25.56 ? 149 VAL B CG1 1 ATOM 4636 C CG2 . VAL B 1 176 ? -31.382 14.077 20.289 1.00 25.45 ? 149 VAL B CG2 1 ATOM 4637 N N . SER B 1 177 ? -28.572 13.402 23.811 1.00 22.66 ? 150 SER B N 1 ATOM 4638 C CA . SER B 1 177 ? -27.352 13.500 24.652 1.00 23.02 ? 150 SER B CA 1 ATOM 4639 C C . SER B 1 177 ? -26.758 12.130 24.985 1.00 25.23 ? 150 SER B C 1 ATOM 4640 O O . SER B 1 177 ? -25.555 11.985 25.074 1.00 23.53 ? 150 SER B O 1 ATOM 4641 C CB . SER B 1 177 ? -27.599 14.271 25.962 1.00 21.88 ? 150 SER B CB 1 ATOM 4642 O OG . SER B 1 177 ? -27.668 15.661 25.686 1.00 22.44 ? 150 SER B OG 1 ATOM 4643 N N . THR B 1 178 ? -27.620 11.138 25.213 1.00 26.37 ? 151 THR B N 1 ATOM 4644 C CA . THR B 1 178 ? -27.181 9.792 25.448 1.00 28.02 ? 151 THR B CA 1 ATOM 4645 C C . THR B 1 178 ? -26.349 9.239 24.313 1.00 28.45 ? 151 THR B C 1 ATOM 4646 O O . THR B 1 178 ? -25.305 8.677 24.541 1.00 27.27 ? 151 THR B O 1 ATOM 4647 C CB . THR B 1 178 ? -28.410 8.893 25.640 1.00 28.97 ? 151 THR B CB 1 ATOM 4648 O OG1 . THR B 1 178 ? -28.953 9.173 26.920 1.00 32.65 ? 151 THR B OG1 1 ATOM 4649 C CG2 . THR B 1 178 ? -28.068 7.439 25.589 1.00 31.95 ? 151 THR B CG2 1 ATOM 4650 N N . ALA B 1 179 ? -26.850 9.352 23.100 1.00 28.29 ? 152 ALA B N 1 ATOM 4651 C CA . ALA B 1 179 ? -26.150 8.824 21.942 1.00 26.94 ? 152 ALA B CA 1 ATOM 4652 C C . ALA B 1 179 ? -24.871 9.581 21.722 1.00 26.76 ? 152 ALA B C 1 ATOM 4653 O O . ALA B 1 179 ? -23.860 8.989 21.401 1.00 28.16 ? 152 ALA B O 1 ATOM 4654 C CB . ALA B 1 179 ? -27.029 8.902 20.722 1.00 27.24 ? 152 ALA B CB 1 ATOM 4655 N N . VAL B 1 180 ? -24.908 10.899 21.886 1.00 26.68 ? 153 VAL B N 1 ATOM 4656 C CA . VAL B 1 180 ? -23.681 11.699 21.821 1.00 26.03 ? 153 VAL B CA 1 ATOM 4657 C C . VAL B 1 180 ? -22.683 11.253 22.905 1.00 26.19 ? 153 VAL B C 1 ATOM 4658 O O . VAL B 1 180 ? -21.512 11.051 22.616 1.00 28.15 ? 153 VAL B O 1 ATOM 4659 C CB . VAL B 1 180 ? -23.976 13.194 21.938 1.00 25.98 ? 153 VAL B CB 1 ATOM 4660 C CG1 . VAL B 1 180 ? -22.700 14.003 22.040 1.00 26.65 ? 153 VAL B CG1 1 ATOM 4661 C CG2 . VAL B 1 180 ? -24.749 13.660 20.713 1.00 28.95 ? 153 VAL B CG2 1 ATOM 4662 N N . ALA B 1 181 ? -23.160 11.038 24.124 1.00 27.01 ? 154 ALA B N 1 ATOM 4663 C CA . ALA B 1 181 ? -22.285 10.661 25.249 1.00 28.77 ? 154 ALA B CA 1 ATOM 4664 C C . ALA B 1 181 ? -21.602 9.314 25.079 1.00 29.24 ? 154 ALA B C 1 ATOM 4665 O O . ALA B 1 181 ? -20.460 9.140 25.514 1.00 29.54 ? 154 ALA B O 1 ATOM 4666 C CB . ALA B 1 181 ? -23.046 10.691 26.565 1.00 27.79 ? 154 ALA B CB 1 ATOM 4667 N N . ASN B 1 182 ? -22.292 8.361 24.461 1.00 28.88 ? 155 ASN B N 1 ATOM 4668 C CA . ASN B 1 182 ? -21.709 7.055 24.209 1.00 29.44 ? 155 ASN B CA 1 ATOM 4669 C C . ASN B 1 182 ? -20.472 7.184 23.319 1.00 29.99 ? 155 ASN B C 1 ATOM 4670 O O . ASN B 1 182 ? -19.490 6.448 23.497 1.00 30.45 ? 155 ASN B O 1 ATOM 4671 C CB . ASN B 1 182 ? -22.694 6.136 23.501 1.00 32.17 ? 155 ASN B CB 1 ATOM 4672 C CG . ASN B 1 182 ? -23.802 5.609 24.412 1.00 34.18 ? 155 ASN B CG 1 ATOM 4673 O OD1 . ASN B 1 182 ? -23.591 5.350 25.592 1.00 34.79 ? 155 ASN B OD1 1 ATOM 4674 N ND2 . ASN B 1 182 ? -24.977 5.393 23.826 1.00 36.57 ? 155 ASN B ND2 1 ATOM 4675 N N . LEU B 1 183 ? -20.505 8.143 22.400 1.00 28.65 ? 156 LEU B N 1 ATOM 4676 C CA . LEU B 1 183 ? -19.380 8.386 21.491 1.00 32.64 ? 156 LEU B CA 1 ATOM 4677 C C . LEU B 1 183 ? -18.269 9.261 22.106 1.00 31.70 ? 156 LEU B C 1 ATOM 4678 O O . LEU B 1 183 ? -17.101 8.907 22.079 1.00 32.10 ? 156 LEU B O 1 ATOM 4679 C CB . LEU B 1 183 ? -19.914 8.999 20.205 1.00 35.29 ? 156 LEU B CB 1 ATOM 4680 C CG . LEU B 1 183 ? -19.353 8.609 18.842 1.00 41.58 ? 156 LEU B CG 1 ATOM 4681 C CD1 . LEU B 1 183 ? -19.499 9.761 17.866 1.00 42.81 ? 156 LEU B CD1 1 ATOM 4682 C CD2 . LEU B 1 183 ? -17.910 8.113 18.898 1.00 42.60 ? 156 LEU B CD2 1 ATOM 4683 N N . LEU B 1 184 ? -18.637 10.391 22.691 1.00 30.04 ? 157 LEU B N 1 ATOM 4684 C CA . LEU B 1 184 ? -17.661 11.264 23.318 1.00 29.31 ? 157 LEU B CA 1 ATOM 4685 C C . LEU B 1 184 ? -16.931 10.603 24.472 1.00 30.33 ? 157 LEU B C 1 ATOM 4686 O O . LEU B 1 184 ? -15.731 10.816 24.650 1.00 28.79 ? 157 LEU B O 1 ATOM 4687 C CB . LEU B 1 184 ? -18.325 12.561 23.784 1.00 28.26 ? 157 LEU B CB 1 ATOM 4688 C CG . LEU B 1 184 ? -18.822 13.450 22.641 1.00 27.62 ? 157 LEU B CG 1 ATOM 4689 C CD1 . LEU B 1 184 ? -19.509 14.660 23.243 1.00 27.50 ? 157 LEU B CD1 1 ATOM 4690 C CD2 . LEU B 1 184 ? -17.712 13.918 21.701 1.00 29.63 ? 157 LEU B CD2 1 ATOM 4691 N N . GLY B 1 185 ? -17.657 9.803 25.247 1.00 30.53 ? 158 GLY B N 1 ATOM 4692 C CA . GLY B 1 185 ? -17.098 9.098 26.382 1.00 31.52 ? 158 GLY B CA 1 ATOM 4693 C C . GLY B 1 185 ? -16.008 8.115 26.016 1.00 33.88 ? 158 GLY B C 1 ATOM 4694 O O . GLY B 1 185 ? -15.111 7.843 26.827 1.00 34.98 ? 158 GLY B O 1 ATOM 4695 N N . LEU B 1 186 ? -16.066 7.596 24.797 1.00 34.40 ? 159 LEU B N 1 ATOM 4696 C CA . LEU B 1 186 ? -14.997 6.759 24.290 1.00 37.40 ? 159 LEU B CA 1 ATOM 4697 C C . LEU B 1 186 ? -13.645 7.443 24.306 1.00 39.70 ? 159 LEU B C 1 ATOM 4698 O O . LEU B 1 186 ? -12.643 6.783 24.538 1.00 37.48 ? 159 LEU B O 1 ATOM 4699 C CB . LEU B 1 186 ? -15.254 6.348 22.852 1.00 40.78 ? 159 LEU B CB 1 ATOM 4700 C CG . LEU B 1 186 ? -16.148 5.156 22.598 1.00 42.41 ? 159 LEU B CG 1 ATOM 4701 C CD1 . LEU B 1 186 ? -16.177 4.918 21.091 1.00 42.50 ? 159 LEU B CD1 1 ATOM 4702 C CD2 . LEU B 1 186 ? -15.584 3.958 23.336 1.00 43.31 ? 159 LEU B CD2 1 ATOM 4703 N N . PHE B 1 187 ? -13.628 8.746 24.030 1.00 37.81 ? 160 PHE B N 1 ATOM 4704 C CA . PHE B 1 187 ? -12.395 9.514 23.938 1.00 35.29 ? 160 PHE B CA 1 ATOM 4705 C C . PHE B 1 187 ? -12.174 10.416 25.132 1.00 34.48 ? 160 PHE B C 1 ATOM 4706 O O . PHE B 1 187 ? -11.305 11.295 25.111 1.00 36.17 ? 160 PHE B O 1 ATOM 4707 C CB . PHE B 1 187 ? -12.448 10.324 22.643 1.00 36.84 ? 160 PHE B CB 1 ATOM 4708 C CG . PHE B 1 187 ? -12.709 9.469 21.452 1.00 42.84 ? 160 PHE B CG 1 ATOM 4709 C CD1 . PHE B 1 187 ? -11.746 8.536 21.042 1.00 46.60 ? 160 PHE B CD1 1 ATOM 4710 C CD2 . PHE B 1 187 ? -13.925 9.513 20.784 1.00 41.37 ? 160 PHE B CD2 1 ATOM 4711 C CE1 . PHE B 1 187 ? -11.988 7.700 19.956 1.00 51.34 ? 160 PHE B CE1 1 ATOM 4712 C CE2 . PHE B 1 187 ? -14.162 8.691 19.700 1.00 43.72 ? 160 PHE B CE2 1 ATOM 4713 C CZ . PHE B 1 187 ? -13.208 7.773 19.287 1.00 47.22 ? 160 PHE B CZ 1 ATOM 4714 N N . TYR B 1 188 ? -13.001 10.243 26.157 1.00 31.12 ? 161 TYR B N 1 ATOM 4715 C CA . TYR B 1 188 ? -12.955 11.088 27.345 1.00 31.63 ? 161 TYR B CA 1 ATOM 4716 C C . TYR B 1 188 ? -13.027 12.555 27.032 1.00 31.19 ? 161 TYR B C 1 ATOM 4717 O O . TYR B 1 188 ? -12.360 13.376 27.674 1.00 33.36 ? 161 TYR B O 1 ATOM 4718 C CB . TYR B 1 188 ? -11.708 10.760 28.189 1.00 32.55 ? 161 TYR B CB 1 ATOM 4719 C CG . TYR B 1 188 ? -11.813 9.387 28.777 1.00 31.77 ? 161 TYR B CG 1 ATOM 4720 C CD1 . TYR B 1 188 ? -11.450 8.266 28.047 1.00 32.94 ? 161 TYR B CD1 1 ATOM 4721 C CD2 . TYR B 1 188 ? -12.331 9.200 30.050 1.00 33.94 ? 161 TYR B CD2 1 ATOM 4722 C CE1 . TYR B 1 188 ? -11.568 6.995 28.578 1.00 34.18 ? 161 TYR B CE1 1 ATOM 4723 C CE2 . TYR B 1 188 ? -12.450 7.934 30.593 1.00 35.67 ? 161 TYR B CE2 1 ATOM 4724 C CZ . TYR B 1 188 ? -12.063 6.835 29.851 1.00 36.94 ? 161 TYR B CZ 1 ATOM 4725 O OH . TYR B 1 188 ? -12.176 5.568 30.399 1.00 46.19 ? 161 TYR B OH 1 ATOM 4726 N N . ILE B 1 189 ? -13.840 12.894 26.034 1.00 29.36 ? 162 ILE B N 1 ATOM 4727 C CA . ILE B 1 189 ? -14.114 14.278 25.735 1.00 28.62 ? 162 ILE B CA 1 ATOM 4728 C C . ILE B 1 189 ? -15.265 14.738 26.614 1.00 26.93 ? 162 ILE B C 1 ATOM 4729 O O . ILE B 1 189 ? -16.332 14.163 26.569 1.00 26.38 ? 162 ILE B O 1 ATOM 4730 C CB . ILE B 1 189 ? -14.460 14.464 24.257 1.00 30.77 ? 162 ILE B CB 1 ATOM 4731 C CG1 . ILE B 1 189 ? -13.212 14.127 23.425 1.00 33.89 ? 162 ILE B CG1 1 ATOM 4732 C CG2 . ILE B 1 189 ? -14.908 15.888 23.993 1.00 29.27 ? 162 ILE B CG2 1 ATOM 4733 C CD1 . ILE B 1 189 ? -13.482 13.937 21.954 1.00 34.75 ? 162 ILE B CD1 1 ATOM 4734 N N . PRO B 1 190 ? -15.049 15.787 27.408 1.00 26.65 ? 163 PRO B N 1 ATOM 4735 C CA . PRO B 1 190 ? -16.134 16.241 28.292 1.00 26.13 ? 163 PRO B CA 1 ATOM 4736 C C . PRO B 1 190 ? -17.283 16.805 27.521 1.00 25.90 ? 163 PRO B C 1 ATOM 4737 O O . PRO B 1 190 ? -17.091 17.499 26.492 1.00 28.96 ? 163 PRO B O 1 ATOM 4738 C CB . PRO B 1 190 ? -15.478 17.335 29.147 1.00 25.57 ? 163 PRO B CB 1 ATOM 4739 C CG . PRO B 1 190 ? -14.304 17.790 28.361 1.00 26.46 ? 163 PRO B CG 1 ATOM 4740 C CD . PRO B 1 190 ? -13.824 16.583 27.594 1.00 26.41 ? 163 PRO B CD 1 ATOM 4741 N N . GLN B 1 191 ? -18.466 16.527 28.032 1.00 24.69 ? 164 GLN B N 1 ATOM 4742 C CA . GLN B 1 191 ? -19.711 16.987 27.456 1.00 24.25 ? 164 GLN B CA 1 ATOM 4743 C C . GLN B 1 191 ? -20.506 17.598 28.577 1.00 23.24 ? 164 GLN B C 1 ATOM 4744 O O . GLN B 1 191 ? -20.733 16.937 29.598 1.00 23.75 ? 164 GLN B O 1 ATOM 4745 C CB . GLN B 1 191 ? -20.467 15.790 26.857 1.00 24.29 ? 164 GLN B CB 1 ATOM 4746 C CG . GLN B 1 191 ? -21.816 16.135 26.208 1.00 22.97 ? 164 GLN B CG 1 ATOM 4747 C CD . GLN B 1 191 ? -22.611 14.895 25.799 1.00 24.46 ? 164 GLN B CD 1 ATOM 4748 O OE1 . GLN B 1 191 ? -22.090 13.780 25.771 1.00 26.00 ? 164 GLN B OE1 1 ATOM 4749 N NE2 . GLN B 1 191 ? -23.881 15.091 25.459 1.00 25.29 ? 164 GLN B NE2 1 ATOM 4750 N N . VAL B 1 192 ? -20.930 18.845 28.391 1.00 22.54 ? 165 VAL B N 1 ATOM 4751 C CA . VAL B 1 192 ? -21.706 19.566 29.391 1.00 23.66 ? 165 VAL B CA 1 ATOM 4752 C C . VAL B 1 192 ? -23.046 19.899 28.779 1.00 24.19 ? 165 VAL B C 1 ATOM 4753 O O . VAL B 1 192 ? -23.124 20.762 27.901 1.00 25.71 ? 165 VAL B O 1 ATOM 4754 C CB . VAL B 1 192 ? -21.008 20.853 29.884 1.00 23.88 ? 165 VAL B CB 1 ATOM 4755 C CG1 . VAL B 1 192 ? -21.775 21.454 31.067 1.00 25.45 ? 165 VAL B CG1 1 ATOM 4756 C CG2 . VAL B 1 192 ? -19.586 20.569 30.294 1.00 24.60 ? 165 VAL B CG2 1 ATOM 4757 N N . SER B 1 193 ? -24.107 19.217 29.223 1.00 23.21 ? 166 SER B N 1 ATOM 4758 C CA . SER B 1 193 ? -25.425 19.496 28.669 1.00 23.85 ? 166 SER B CA 1 ATOM 4759 C C . SER B 1 193 ? -26.116 20.576 29.452 1.00 24.37 ? 166 SER B C 1 ATOM 4760 O O . SER B 1 193 ? -26.049 20.617 30.684 1.00 23.21 ? 166 SER B O 1 ATOM 4761 C CB . SER B 1 193 ? -26.318 18.274 28.642 1.00 25.52 ? 166 SER B CB 1 ATOM 4762 O OG . SER B 1 193 ? -27.597 18.628 28.131 1.00 25.42 ? 166 SER B OG 1 ATOM 4763 N N . TYR B 1 194 ? -26.772 21.453 28.701 1.00 25.19 ? 167 TYR B N 1 ATOM 4764 C CA . TYR B 1 194 ? -27.520 22.577 29.228 1.00 26.92 ? 167 TYR B CA 1 ATOM 4765 C C . TYR B 1 194 ? -28.998 22.212 29.470 1.00 26.88 ? 167 TYR B C 1 ATOM 4766 O O . TYR B 1 194 ? -29.720 22.962 30.108 1.00 25.88 ? 167 TYR B O 1 ATOM 4767 C CB . TYR B 1 194 ? -27.393 23.807 28.279 1.00 26.99 ? 167 TYR B CB 1 ATOM 4768 C CG . TYR B 1 194 ? -27.687 23.469 26.841 1.00 26.16 ? 167 TYR B CG 1 ATOM 4769 C CD1 . TYR B 1 194 ? -28.998 23.333 26.393 1.00 27.05 ? 167 TYR B CD1 1 ATOM 4770 C CD2 . TYR B 1 194 ? -26.661 23.201 25.948 1.00 25.45 ? 167 TYR B CD2 1 ATOM 4771 C CE1 . TYR B 1 194 ? -29.276 22.978 25.092 1.00 25.44 ? 167 TYR B CE1 1 ATOM 4772 C CE2 . TYR B 1 194 ? -26.923 22.838 24.651 1.00 24.67 ? 167 TYR B CE2 1 ATOM 4773 C CZ . TYR B 1 194 ? -28.232 22.719 24.221 1.00 26.78 ? 167 TYR B CZ 1 ATOM 4774 O OH . TYR B 1 194 ? -28.493 22.358 22.907 1.00 24.62 ? 167 TYR B OH 1 ATOM 4775 N N . ALA B 1 195 ? -29.447 21.057 28.989 1.00 28.28 ? 168 ALA B N 1 ATOM 4776 C CA . ALA B 1 195 ? -30.872 20.707 29.103 1.00 26.27 ? 168 ALA B CA 1 ATOM 4777 C C . ALA B 1 195 ? -31.270 19.246 29.298 1.00 25.16 ? 168 ALA B C 1 ATOM 4778 O O . ALA B 1 195 ? -32.427 18.972 29.577 1.00 25.21 ? 168 ALA B O 1 ATOM 4779 C CB . ALA B 1 195 ? -31.605 21.261 27.895 1.00 25.84 ? 168 ALA B CB 1 ATOM 4780 N N . SER B 1 196 ? -30.359 18.295 29.124 1.00 25.47 ? 169 SER B N 1 ATOM 4781 C CA . SER B 1 196 ? -30.724 16.883 29.216 1.00 25.81 ? 169 SER B CA 1 ATOM 4782 C C . SER B 1 196 ? -30.806 16.487 30.675 1.00 25.81 ? 169 SER B C 1 ATOM 4783 O O . SER B 1 196 ? -29.786 16.423 31.378 1.00 28.00 ? 169 SER B O 1 ATOM 4784 C CB . SER B 1 196 ? -29.695 16.002 28.490 1.00 27.01 ? 169 SER B CB 1 ATOM 4785 O OG . SER B 1 196 ? -29.688 16.313 27.112 1.00 26.38 ? 169 SER B OG 1 ATOM 4786 N N . SER B 1 197 ? -32.012 16.188 31.118 1.00 25.33 ? 170 SER B N 1 ATOM 4787 C CA . SER B 1 197 ? -32.282 16.004 32.527 1.00 23.92 ? 170 SER B CA 1 ATOM 4788 C C . SER B 1 197 ? -32.564 14.577 32.954 1.00 24.03 ? 170 SER B C 1 ATOM 4789 O O . SER B 1 197 ? -32.787 14.329 34.141 1.00 23.89 ? 170 SER B O 1 ATOM 4790 C CB . SER B 1 197 ? -33.464 16.894 32.929 1.00 25.28 ? 170 SER B CB 1 ATOM 4791 O OG . SER B 1 197 ? -34.599 16.643 32.101 1.00 24.06 ? 170 SER B OG 1 ATOM 4792 N N . SER B 1 198 ? -32.488 13.611 32.047 1.00 23.42 ? 171 SER B N 1 ATOM 4793 C CA . SER B 1 198 ? -32.774 12.235 32.422 1.00 22.10 ? 171 SER B CA 1 ATOM 4794 C C . SER B 1 198 ? -31.845 11.703 33.532 1.00 25.44 ? 171 SER B C 1 ATOM 4795 O O . SER B 1 198 ? -30.618 11.908 33.487 1.00 27.15 ? 171 SER B O 1 ATOM 4796 C CB . SER B 1 198 ? -32.640 11.312 31.223 1.00 22.77 ? 171 SER B CB 1 ATOM 4797 O OG . SER B 1 198 ? -32.851 9.955 31.614 1.00 22.29 ? 171 SER B OG 1 ATOM 4798 N N . ARG B 1 199 ? -32.421 10.979 34.496 1.00 24.58 ? 172 ARG B N 1 ATOM 4799 C CA . ARG B 1 199 ? -31.633 10.311 35.554 1.00 25.13 ? 172 ARG B CA 1 ATOM 4800 C C . ARG B 1 199 ? -30.649 9.310 34.976 1.00 23.88 ? 172 ARG B C 1 ATOM 4801 O O . ARG B 1 199 ? -29.659 8.982 35.620 1.00 26.63 ? 172 ARG B O 1 ATOM 4802 C CB . ARG B 1 199 ? -32.534 9.519 36.539 1.00 25.85 ? 172 ARG B CB 1 ATOM 4803 C CG . ARG B 1 199 ? -33.001 8.185 35.976 1.00 26.24 ? 172 ARG B CG 1 ATOM 4804 C CD . ARG B 1 199 ? -33.542 7.248 37.012 1.00 28.56 ? 172 ARG B CD 1 ATOM 4805 N NE . ARG B 1 199 ? -34.056 6.008 36.436 1.00 28.18 ? 172 ARG B NE 1 ATOM 4806 C CZ . ARG B 1 199 ? -33.355 4.893 36.232 1.00 26.69 ? 172 ARG B CZ 1 ATOM 4807 N NH1 . ARG B 1 199 ? -32.074 4.801 36.538 1.00 27.23 ? 172 ARG B NH1 1 ATOM 4808 N NH2 . ARG B 1 199 ? -33.962 3.838 35.728 1.00 27.63 ? 172 ARG B NH2 1 ATOM 4809 N N . LEU B 1 200 ? -30.920 8.817 33.777 1.00 24.29 ? 173 LEU B N 1 ATOM 4810 C CA . LEU B 1 200 ? -30.083 7.789 33.156 1.00 25.74 ? 173 LEU B CA 1 ATOM 4811 C C . LEU B 1 200 ? -28.687 8.289 32.885 1.00 26.79 ? 173 LEU B C 1 ATOM 4812 O O . LEU B 1 200 ? -27.703 7.540 33.062 1.00 26.05 ? 173 LEU B O 1 ATOM 4813 C CB . LEU B 1 200 ? -30.731 7.274 31.877 1.00 27.79 ? 173 LEU B CB 1 ATOM 4814 C CG . LEU B 1 200 ? -32.116 6.644 32.023 1.00 30.56 ? 173 LEU B CG 1 ATOM 4815 C CD1 . LEU B 1 200 ? -32.676 6.267 30.651 1.00 33.29 ? 173 LEU B CD1 1 ATOM 4816 C CD2 . LEU B 1 200 ? -32.094 5.434 32.925 1.00 31.50 ? 173 LEU B CD2 1 ATOM 4817 N N . LEU B 1 201 ? -28.580 9.581 32.567 1.00 24.82 ? 174 LEU B N 1 ATOM 4818 C CA . LEU B 1 201 ? -27.264 10.218 32.346 1.00 25.55 ? 174 LEU B CA 1 ATOM 4819 C C . LEU B 1 201 ? -26.387 10.448 33.605 1.00 27.60 ? 174 LEU B C 1 ATOM 4820 O O . LEU B 1 201 ? -25.216 10.839 33.477 1.00 26.94 ? 174 LEU B O 1 ATOM 4821 C CB . LEU B 1 201 ? -27.470 11.552 31.616 1.00 24.97 ? 174 LEU B CB 1 ATOM 4822 C CG . LEU B 1 201 ? -27.925 11.376 30.170 1.00 25.00 ? 174 LEU B CG 1 ATOM 4823 C CD1 . LEU B 1 201 ? -28.651 12.604 29.662 1.00 24.28 ? 174 LEU B CD1 1 ATOM 4824 C CD2 . LEU B 1 201 ? -26.742 11.078 29.256 1.00 26.50 ? 174 LEU B CD2 1 ATOM 4825 N N . SER B 1 202 ? -26.947 10.228 34.803 1.00 27.82 ? 175 SER B N 1 ATOM 4826 C CA . SER B 1 202 ? -26.182 10.296 36.054 1.00 29.32 ? 175 SER B CA 1 ATOM 4827 C C . SER B 1 202 ? -25.261 9.095 36.289 1.00 31.33 ? 175 SER B C 1 ATOM 4828 O O . SER B 1 202 ? -24.459 9.103 37.218 1.00 31.67 ? 175 SER B O 1 ATOM 4829 C CB . SER B 1 202 ? -27.123 10.376 37.263 1.00 30.63 ? 175 SER B CB 1 ATOM 4830 O OG . SER B 1 202 ? -27.822 11.611 37.268 1.00 31.41 ? 175 SER B OG 1 ATOM 4831 N N . ASN B 1 203 ? -25.416 8.058 35.483 1.00 31.81 ? 176 ASN B N 1 ATOM 4832 C CA . ASN B 1 203 ? -24.622 6.844 35.600 1.00 32.38 ? 176 ASN B CA 1 ATOM 4833 C C . ASN B 1 203 ? -23.223 7.053 34.975 1.00 33.37 ? 176 ASN B C 1 ATOM 4834 O O . ASN B 1 203 ? -23.072 7.031 33.741 1.00 29.59 ? 176 ASN B O 1 ATOM 4835 C CB . ASN B 1 203 ? -25.388 5.745 34.874 1.00 33.91 ? 176 ASN B CB 1 ATOM 4836 C CG . ASN B 1 203 ? -24.731 4.367 34.972 1.00 38.22 ? 176 ASN B CG 1 ATOM 4837 O OD1 . ASN B 1 203 ? -25.362 3.360 34.662 1.00 43.18 ? 176 ASN B OD1 1 ATOM 4838 N ND2 . ASN B 1 203 ? -23.513 4.309 35.418 1.00 37.16 ? 176 ASN B ND2 1 ATOM 4839 N N . LYS B 1 204 ? -22.217 7.250 35.824 1.00 33.51 ? 177 LYS B N 1 ATOM 4840 C CA . LYS B 1 204 ? -20.850 7.526 35.355 1.00 38.05 ? 177 LYS B CA 1 ATOM 4841 C C . LYS B 1 204 ? -20.081 6.282 34.889 1.00 38.46 ? 177 LYS B C 1 ATOM 4842 O O . LYS B 1 204 ? -19.077 6.426 34.202 1.00 40.86 ? 177 LYS B O 1 ATOM 4843 C CB . LYS B 1 204 ? -20.018 8.296 36.387 1.00 38.25 ? 177 LYS B CB 1 ATOM 4844 C CG . LYS B 1 204 ? -20.544 9.669 36.785 1.00 39.41 ? 177 LYS B CG 1 ATOM 4845 C CD . LYS B 1 204 ? -20.755 10.640 35.614 1.00 41.63 ? 177 LYS B CD 1 ATOM 4846 C CE . LYS B 1 204 ? -22.138 10.480 34.955 1.00 40.68 ? 177 LYS B CE 1 ATOM 4847 N NZ . LYS B 1 204 ? -22.614 11.722 34.316 1.00 39.76 ? 177 LYS B NZ 1 ATOM 4848 N N . ASN B 1 205 ? -20.562 5.086 35.200 1.00 38.89 ? 178 ASN B N 1 ATOM 4849 C CA . ASN B 1 205 ? -20.050 3.888 34.542 1.00 42.62 ? 178 ASN B CA 1 ATOM 4850 C C . ASN B 1 205 ? -20.332 3.867 33.061 1.00 43.51 ? 178 ASN B C 1 ATOM 4851 O O . ASN B 1 205 ? -19.467 3.503 32.287 1.00 45.11 ? 178 ASN B O 1 ATOM 4852 C CB . ASN B 1 205 ? -20.643 2.616 35.140 1.00 46.98 ? 178 ASN B CB 1 ATOM 4853 C CG . ASN B 1 205 ? -20.187 2.385 36.550 1.00 53.93 ? 178 ASN B CG 1 ATOM 4854 O OD1 . ASN B 1 205 ? -19.063 2.750 36.914 1.00 59.96 ? 178 ASN B OD1 1 ATOM 4855 N ND2 . ASN B 1 205 ? -21.062 1.810 37.372 1.00 56.73 ? 178 ASN B ND2 1 ATOM 4856 N N . GLN B 1 206 ? -21.550 4.225 32.661 1.00 40.09 ? 179 GLN B N 1 ATOM 4857 C CA . GLN B 1 206 ? -21.884 4.274 31.252 1.00 38.37 ? 179 GLN B CA 1 ATOM 4858 C C . GLN B 1 206 ? -21.447 5.580 30.595 1.00 35.80 ? 179 GLN B C 1 ATOM 4859 O O . GLN B 1 206 ? -20.973 5.570 29.466 1.00 35.14 ? 179 GLN B O 1 ATOM 4860 C CB . GLN B 1 206 ? -23.375 4.038 31.014 1.00 42.74 ? 179 GLN B CB 1 ATOM 4861 C CG . GLN B 1 206 ? -23.728 4.227 29.540 1.00 48.01 ? 179 GLN B CG 1 ATOM 4862 C CD . GLN B 1 206 ? -24.558 3.138 28.900 1.00 54.37 ? 179 GLN B CD 1 ATOM 4863 O OE1 . GLN B 1 206 ? -25.317 3.409 27.949 1.00 58.23 ? 179 GLN B OE1 1 ATOM 4864 N NE2 . GLN B 1 206 ? -24.383 1.893 29.353 1.00 57.80 ? 179 GLN B NE2 1 ATOM 4865 N N . PHE B 1 207 ? -21.609 6.699 31.288 1.00 33.33 ? 180 PHE B N 1 ATOM 4866 C CA . PHE B 1 207 ? -21.406 8.010 30.694 1.00 30.84 ? 180 PHE B CA 1 ATOM 4867 C C . PHE B 1 207 ? -20.246 8.711 31.420 1.00 31.25 ? 180 PHE B C 1 ATOM 4868 O O . PHE B 1 207 ? -20.427 9.650 32.222 1.00 33.89 ? 180 PHE B O 1 ATOM 4869 C CB . PHE B 1 207 ? -22.697 8.837 30.723 1.00 28.39 ? 180 PHE B CB 1 ATOM 4870 C CG . PHE B 1 207 ? -23.867 8.155 30.066 1.00 28.60 ? 180 PHE B CG 1 ATOM 4871 C CD1 . PHE B 1 207 ? -23.903 7.986 28.692 1.00 28.60 ? 180 PHE B CD1 1 ATOM 4872 C CD2 . PHE B 1 207 ? -24.934 7.681 30.821 1.00 27.35 ? 180 PHE B CD2 1 ATOM 4873 C CE1 . PHE B 1 207 ? -24.977 7.356 28.078 1.00 27.07 ? 180 PHE B CE1 1 ATOM 4874 C CE2 . PHE B 1 207 ? -26.016 7.057 30.219 1.00 27.77 ? 180 PHE B CE2 1 ATOM 4875 C CZ . PHE B 1 207 ? -26.029 6.867 28.848 1.00 26.98 ? 180 PHE B CZ 1 ATOM 4876 N N . LYS B 1 208 ? -19.049 8.296 31.034 1.00 31.67 ? 181 LYS B N 1 ATOM 4877 C CA . LYS B 1 208 ? -17.832 8.668 31.720 1.00 33.58 ? 181 LYS B CA 1 ATOM 4878 C C . LYS B 1 208 ? -17.444 10.113 31.566 1.00 30.85 ? 181 LYS B C 1 ATOM 4879 O O . LYS B 1 208 ? -16.781 10.641 32.447 1.00 30.45 ? 181 LYS B O 1 ATOM 4880 C CB . LYS B 1 208 ? -16.686 7.843 31.211 1.00 38.72 ? 181 LYS B CB 1 ATOM 4881 C CG . LYS B 1 208 ? -16.772 6.386 31.580 1.00 43.00 ? 181 LYS B CG 1 ATOM 4882 C CD . LYS B 1 208 ? -15.770 5.632 30.755 1.00 47.81 ? 181 LYS B CD 1 ATOM 4883 C CE . LYS B 1 208 ? -15.764 4.162 31.119 1.00 55.58 ? 181 LYS B CE 1 ATOM 4884 N NZ . LYS B 1 208 ? -14.759 3.473 30.250 1.00 62.06 ? 181 LYS B NZ 1 ATOM 4885 N N . SER B 1 209 ? -17.875 10.776 30.493 1.00 25.88 ? 182 SER B N 1 ATOM 4886 C CA . SER B 1 209 ? -17.461 12.162 30.280 1.00 25.66 ? 182 SER B CA 1 ATOM 4887 C C . SER B 1 209 ? -18.591 13.196 30.323 1.00 24.32 ? 182 SER B C 1 ATOM 4888 O O . SER B 1 209 ? -18.401 14.337 29.909 1.00 24.85 ? 182 SER B O 1 ATOM 4889 C CB . SER B 1 209 ? -16.682 12.272 28.973 1.00 26.15 ? 182 SER B CB 1 ATOM 4890 O OG . SER B 1 209 ? -17.527 12.263 27.850 1.00 26.27 ? 182 SER B OG 1 ATOM 4891 N N . PHE B 1 210 ? -19.735 12.819 30.872 1.00 23.83 ? 183 PHE B N 1 ATOM 4892 C CA . PHE B 1 210 ? -20.941 13.653 30.815 1.00 24.60 ? 183 PHE B CA 1 ATOM 4893 C C . PHE B 1 210 ? -21.173 14.420 32.099 1.00 23.27 ? 183 PHE B C 1 ATOM 4894 O O . PHE B 1 210 ? -21.157 13.851 33.190 1.00 23.94 ? 183 PHE B O 1 ATOM 4895 C CB . PHE B 1 210 ? -22.176 12.795 30.514 1.00 24.56 ? 183 PHE B CB 1 ATOM 4896 C CG . PHE B 1 210 ? -23.467 13.586 30.430 1.00 24.90 ? 183 PHE B CG 1 ATOM 4897 C CD1 . PHE B 1 210 ? -24.228 13.829 31.557 1.00 23.62 ? 183 PHE B CD1 1 ATOM 4898 C CD2 . PHE B 1 210 ? -23.908 14.080 29.217 1.00 25.29 ? 183 PHE B CD2 1 ATOM 4899 C CE1 . PHE B 1 210 ? -25.396 14.563 31.478 1.00 25.07 ? 183 PHE B CE1 1 ATOM 4900 C CE2 . PHE B 1 210 ? -25.083 14.809 29.128 1.00 27.33 ? 183 PHE B CE2 1 ATOM 4901 C CZ . PHE B 1 210 ? -25.838 15.042 30.254 1.00 26.19 ? 183 PHE B CZ 1 ATOM 4902 N N . LEU B 1 211 ? -21.447 15.707 31.943 1.00 23.88 ? 184 LEU B N 1 ATOM 4903 C CA . LEU B 1 211 ? -21.854 16.577 33.022 1.00 24.74 ? 184 LEU B CA 1 ATOM 4904 C C . LEU B 1 211 ? -22.979 17.437 32.528 1.00 23.12 ? 184 LEU B C 1 ATOM 4905 O O . LEU B 1 211 ? -23.250 17.490 31.352 1.00 23.50 ? 184 LEU B O 1 ATOM 4906 C CB . LEU B 1 211 ? -20.705 17.471 33.455 1.00 29.38 ? 184 LEU B CB 1 ATOM 4907 C CG . LEU B 1 211 ? -19.437 16.737 33.861 1.00 33.94 ? 184 LEU B CG 1 ATOM 4908 C CD1 . LEU B 1 211 ? -18.392 16.889 32.788 1.00 35.17 ? 184 LEU B CD1 1 ATOM 4909 C CD2 . LEU B 1 211 ? -18.909 17.242 35.195 1.00 38.42 ? 184 LEU B CD2 1 ATOM 4910 N N . ARG B 1 212 ? -23.628 18.152 33.424 1.00 24.25 ? 185 ARG B N 1 ATOM 4911 C CA . ARG B 1 212 ? -24.710 19.023 33.014 1.00 24.31 ? 185 ARG B CA 1 ATOM 4912 C C . ARG B 1 212 ? -24.953 20.159 33.979 1.00 26.10 ? 185 ARG B C 1 ATOM 4913 O O . ARG B 1 212 ? -24.700 20.054 35.184 1.00 27.09 ? 185 ARG B O 1 ATOM 4914 C CB . ARG B 1 212 ? -25.990 18.216 32.815 1.00 25.22 ? 185 ARG B CB 1 ATOM 4915 C CG . ARG B 1 212 ? -26.357 17.334 33.984 1.00 24.45 ? 185 ARG B CG 1 ATOM 4916 C CD . ARG B 1 212 ? -27.633 16.580 33.728 1.00 25.69 ? 185 ARG B CD 1 ATOM 4917 N NE . ARG B 1 212 ? -27.775 15.386 34.577 1.00 25.46 ? 185 ARG B NE 1 ATOM 4918 C CZ . ARG B 1 212 ? -28.589 14.372 34.323 1.00 24.91 ? 185 ARG B CZ 1 ATOM 4919 N NH1 . ARG B 1 212 ? -29.397 14.365 33.248 1.00 24.15 ? 185 ARG B NH1 1 ATOM 4920 N NH2 . ARG B 1 212 ? -28.595 13.351 35.138 1.00 25.83 ? 185 ARG B NH2 1 ATOM 4921 N N . THR B 1 213 ? -25.446 21.258 33.432 1.00 27.13 ? 186 THR B N 1 ATOM 4922 C CA . THR B 1 213 ? -25.776 22.429 34.222 1.00 28.69 ? 186 THR B CA 1 ATOM 4923 C C . THR B 1 213 ? -27.267 22.515 34.495 1.00 30.35 ? 186 THR B C 1 ATOM 4924 O O . THR B 1 213 ? -27.745 23.563 34.893 1.00 34.59 ? 186 THR B O 1 ATOM 4925 C CB . THR B 1 213 ? -25.329 23.718 33.521 1.00 28.85 ? 186 THR B CB 1 ATOM 4926 O OG1 . THR B 1 213 ? -25.780 23.710 32.156 1.00 28.03 ? 186 THR B OG1 1 ATOM 4927 C CG2 . THR B 1 213 ? -23.834 23.825 33.548 1.00 28.16 ? 186 THR B CG2 1 ATOM 4928 N N . ILE B 1 214 ? -27.998 21.430 34.259 1.00 31.01 ? 187 ILE B N 1 ATOM 4929 C CA . ILE B 1 214 ? -29.425 21.346 34.587 1.00 30.60 ? 187 ILE B CA 1 ATOM 4930 C C . ILE B 1 214 ? -29.595 20.207 35.576 1.00 30.86 ? 187 ILE B C 1 ATOM 4931 O O . ILE B 1 214 ? -28.883 19.215 35.470 1.00 30.32 ? 187 ILE B O 1 ATOM 4932 C CB . ILE B 1 214 ? -30.280 21.080 33.342 1.00 30.86 ? 187 ILE B CB 1 ATOM 4933 C CG1 . ILE B 1 214 ? -31.761 21.217 33.682 1.00 32.19 ? 187 ILE B CG1 1 ATOM 4934 C CG2 . ILE B 1 214 ? -30.014 19.689 32.747 1.00 29.78 ? 187 ILE B CG2 1 ATOM 4935 C CD1 . ILE B 1 214 ? -32.670 21.276 32.476 1.00 32.15 ? 187 ILE B CD1 1 ATOM 4936 N N . PRO B 1 215 ? -30.532 20.335 36.534 1.00 32.02 ? 188 PRO B N 1 ATOM 4937 C CA . PRO B 1 215 ? -30.694 19.229 37.478 1.00 32.51 ? 188 PRO B CA 1 ATOM 4938 C C . PRO B 1 215 ? -31.405 18.016 36.882 1.00 33.83 ? 188 PRO B C 1 ATOM 4939 O O . PRO B 1 215 ? -32.099 18.106 35.868 1.00 32.09 ? 188 PRO B O 1 ATOM 4940 C CB . PRO B 1 215 ? -31.604 19.805 38.569 1.00 34.59 ? 188 PRO B CB 1 ATOM 4941 C CG . PRO B 1 215 ? -31.626 21.274 38.344 1.00 32.54 ? 188 PRO B CG 1 ATOM 4942 C CD . PRO B 1 215 ? -31.381 21.486 36.894 1.00 31.31 ? 188 PRO B CD 1 ATOM 4943 N N . ASN B 1 216 ? -31.206 16.917 37.579 1.00 30.66 ? 189 ASN B N 1 ATOM 4944 C CA . ASN B 1 216 ? -31.716 15.596 37.299 1.00 34.18 ? 189 ASN B CA 1 ATOM 4945 C C . ASN B 1 216 ? -33.223 15.454 37.626 1.00 34.34 ? 189 ASN B C 1 ATOM 4946 O O . ASN B 1 216 ? -33.690 15.952 38.642 1.00 32.72 ? 189 ASN B O 1 ATOM 4947 C CB . ASN B 1 216 ? -30.794 14.749 38.176 1.00 37.87 ? 189 ASN B CB 1 ATOM 4948 C CG . ASN B 1 216 ? -31.222 13.359 38.386 1.00 37.53 ? 189 ASN B CG 1 ATOM 4949 O OD1 . ASN B 1 216 ? -32.386 13.055 38.493 1.00 38.49 ? 189 ASN B OD1 1 ATOM 4950 N ND2 . ASN B 1 216 ? -30.227 12.498 38.586 1.00 38.03 ? 189 ASN B ND2 1 ATOM 4951 N N . ASP B 1 217 ? -33.978 14.760 36.774 1.00 31.64 ? 190 ASP B N 1 ATOM 4952 C CA . ASP B 1 217 ? -35.425 14.747 36.889 1.00 32.48 ? 190 ASP B CA 1 ATOM 4953 C C . ASP B 1 217 ? -35.967 13.929 38.066 1.00 32.48 ? 190 ASP B C 1 ATOM 4954 O O . ASP B 1 217 ? -37.150 13.977 38.323 1.00 30.98 ? 190 ASP B O 1 ATOM 4955 C CB . ASP B 1 217 ? -36.104 14.239 35.615 1.00 29.98 ? 190 ASP B CB 1 ATOM 4956 C CG . ASP B 1 217 ? -36.130 15.259 34.522 1.00 32.29 ? 190 ASP B CG 1 ATOM 4957 O OD1 . ASP B 1 217 ? -36.276 16.466 34.819 1.00 33.89 ? 190 ASP B OD1 1 ATOM 4958 O OD2 . ASP B 1 217 ? -36.034 14.864 33.338 1.00 30.92 ? 190 ASP B OD2 1 ATOM 4959 N N . GLU B 1 218 ? -35.128 13.194 38.788 1.00 31.13 ? 191 GLU B N 1 ATOM 4960 C CA . GLU B 1 218 ? -35.581 12.567 40.014 1.00 32.62 ? 191 GLU B CA 1 ATOM 4961 C C . GLU B 1 218 ? -36.315 13.579 40.925 1.00 32.30 ? 191 GLU B C 1 ATOM 4962 O O . GLU B 1 218 ? -37.348 13.266 41.536 1.00 34.64 ? 191 GLU B O 1 ATOM 4963 C CB . GLU B 1 218 ? -34.415 11.897 40.754 1.00 32.54 ? 191 GLU B CB 1 ATOM 4964 C CG . GLU B 1 218 ? -33.841 10.694 40.011 1.00 34.66 ? 191 GLU B CG 1 ATOM 4965 C CD . GLU B 1 218 ? -34.644 9.420 40.208 1.00 36.01 ? 191 GLU B CD 1 ATOM 4966 O OE1 . GLU B 1 218 ? -34.405 8.755 41.236 1.00 41.08 ? 191 GLU B OE1 1 ATOM 4967 O OE2 . GLU B 1 218 ? -35.497 9.067 39.354 1.00 33.86 ? 191 GLU B OE2 1 ATOM 4968 N N . HIS B 1 219 ? -35.783 14.783 40.989 1.00 30.63 ? 192 HIS B N 1 ATOM 4969 C CA . HIS B 1 219 ? -36.297 15.814 41.858 1.00 34.17 ? 192 HIS B CA 1 ATOM 4970 C C . HIS B 1 219 ? -37.581 16.441 41.334 1.00 33.13 ? 192 HIS B C 1 ATOM 4971 O O . HIS B 1 219 ? -38.530 16.674 42.087 1.00 32.11 ? 192 HIS B O 1 ATOM 4972 C CB . HIS B 1 219 ? -35.221 16.872 42.008 1.00 37.74 ? 192 HIS B CB 1 ATOM 4973 C CG . HIS B 1 219 ? -33.943 16.315 42.511 1.00 41.47 ? 192 HIS B CG 1 ATOM 4974 N ND1 . HIS B 1 219 ? -33.863 15.651 43.716 1.00 44.66 ? 192 HIS B ND1 1 ATOM 4975 C CD2 . HIS B 1 219 ? -32.718 16.228 41.943 1.00 44.47 ? 192 HIS B CD2 1 ATOM 4976 C CE1 . HIS B 1 219 ? -32.627 15.224 43.896 1.00 46.39 ? 192 HIS B CE1 1 ATOM 4977 N NE2 . HIS B 1 219 ? -31.912 15.562 42.837 1.00 47.20 ? 192 HIS B NE2 1 ATOM 4978 N N . GLN B 1 220 ? -37.613 16.679 40.036 1.00 32.55 ? 193 GLN B N 1 ATOM 4979 C CA . GLN B 1 220 ? -38.806 17.215 39.408 1.00 30.26 ? 193 GLN B CA 1 ATOM 4980 C C . GLN B 1 220 ? -39.984 16.255 39.521 1.00 28.31 ? 193 GLN B C 1 ATOM 4981 O O . GLN B 1 220 ? -41.093 16.676 39.776 1.00 25.13 ? 193 GLN B O 1 ATOM 4982 C CB . GLN B 1 220 ? -38.578 17.516 37.955 1.00 31.93 ? 193 GLN B CB 1 ATOM 4983 C CG . GLN B 1 220 ? -39.642 18.435 37.389 1.00 34.46 ? 193 GLN B CG 1 ATOM 4984 C CD . GLN B 1 220 ? -39.491 18.654 35.908 1.00 37.70 ? 193 GLN B CD 1 ATOM 4985 O OE1 . GLN B 1 220 ? -38.435 18.412 35.315 1.00 47.44 ? 193 GLN B OE1 1 ATOM 4986 N NE2 . GLN B 1 220 ? -40.529 19.106 35.304 1.00 35.16 ? 193 GLN B NE2 1 ATOM 4987 N N . ALA B 1 221 ? -39.738 14.964 39.347 1.00 26.52 ? 194 ALA B N 1 ATOM 4988 C CA . ALA B 1 221 ? -40.813 14.011 39.445 1.00 27.44 ? 194 ALA B CA 1 ATOM 4989 C C . ALA B 1 221 ? -41.347 13.954 40.876 1.00 29.09 ? 194 ALA B C 1 ATOM 4990 O O . ALA B 1 221 ? -42.552 13.845 41.083 1.00 31.67 ? 194 ALA B O 1 ATOM 4991 C CB . ALA B 1 221 ? -40.368 12.640 38.988 1.00 26.59 ? 194 ALA B CB 1 ATOM 4992 N N . THR B 1 222 ? -40.453 14.024 41.852 1.00 28.03 ? 195 THR B N 1 ATOM 4993 C CA . THR B 1 222 ? -40.855 14.044 43.250 1.00 30.36 ? 195 THR B CA 1 ATOM 4994 C C . THR B 1 222 ? -41.676 15.304 43.543 1.00 28.70 ? 195 THR B C 1 ATOM 4995 O O . THR B 1 222 ? -42.720 15.238 44.186 1.00 28.76 ? 195 THR B O 1 ATOM 4996 C CB . THR B 1 222 ? -39.618 13.970 44.179 1.00 30.40 ? 195 THR B CB 1 ATOM 4997 O OG1 . THR B 1 222 ? -38.853 12.816 43.827 1.00 32.79 ? 195 THR B OG1 1 ATOM 4998 C CG2 . THR B 1 222 ? -40.037 13.841 45.627 1.00 31.47 ? 195 THR B CG2 1 ATOM 4999 N N . ALA B 1 223 ? -41.222 16.434 43.035 1.00 27.97 ? 196 ALA B N 1 ATOM 5000 C CA . ALA B 1 223 ? -41.958 17.684 43.199 1.00 30.03 ? 196 ALA B CA 1 ATOM 5001 C C . ALA B 1 223 ? -43.381 17.615 42.645 1.00 31.41 ? 196 ALA B C 1 ATOM 5002 O O . ALA B 1 223 ? -44.310 18.186 43.247 1.00 28.86 ? 196 ALA B O 1 ATOM 5003 C CB . ALA B 1 223 ? -41.227 18.824 42.530 1.00 28.03 ? 196 ALA B CB 1 ATOM 5004 N N . MET B 1 224 ? -43.553 16.960 41.496 1.00 29.47 ? 197 MET B N 1 ATOM 5005 C CA . MET B 1 224 ? -44.904 16.746 40.959 1.00 33.61 ? 197 MET B CA 1 ATOM 5006 C C . MET B 1 224 ? -45.798 15.983 41.939 1.00 31.35 ? 197 MET B C 1 ATOM 5007 O O . MET B 1 224 ? -46.950 16.357 42.163 1.00 30.02 ? 197 MET B O 1 ATOM 5008 C CB . MET B 1 224 ? -44.863 15.968 39.662 1.00 35.90 ? 197 MET B CB 1 ATOM 5009 C CG . MET B 1 224 ? -44.482 16.800 38.479 1.00 43.44 ? 197 MET B CG 1 ATOM 5010 S SD . MET B 1 224 ? -44.076 15.735 37.074 1.00 49.62 ? 197 MET B SD 1 ATOM 5011 C CE . MET B 1 224 ? -44.246 16.945 35.779 1.00 50.22 ? 197 MET B CE 1 ATOM 5012 N N . ALA B 1 225 ? -45.270 14.913 42.526 1.00 31.89 ? 198 ALA B N 1 ATOM 5013 C CA . ALA B 1 225 ? -46.042 14.182 43.545 1.00 32.69 ? 198 ALA B CA 1 ATOM 5014 C C . ALA B 1 225 ? -46.338 15.071 44.765 1.00 32.64 ? 198 ALA B C 1 ATOM 5015 O O . ALA B 1 225 ? -47.463 15.037 45.302 1.00 32.38 ? 198 ALA B O 1 ATOM 5016 C CB . ALA B 1 225 ? -45.326 12.935 43.974 1.00 30.97 ? 198 ALA B CB 1 ATOM 5017 N N . ASP B 1 226 ? -45.352 15.882 45.170 1.00 31.56 ? 199 ASP B N 1 ATOM 5018 C CA . ASP B 1 226 ? -45.532 16.799 46.295 1.00 34.16 ? 199 ASP B CA 1 ATOM 5019 C C . ASP B 1 226 ? -46.649 17.832 46.036 1.00 35.11 ? 199 ASP B C 1 ATOM 5020 O O . ASP B 1 226 ? -47.413 18.117 46.934 1.00 34.64 ? 199 ASP B O 1 ATOM 5021 C CB . ASP B 1 226 ? -44.236 17.536 46.639 1.00 34.28 ? 199 ASP B CB 1 ATOM 5022 C CG . ASP B 1 226 ? -43.294 16.713 47.475 1.00 34.29 ? 199 ASP B CG 1 ATOM 5023 O OD1 . ASP B 1 226 ? -43.722 15.699 48.054 1.00 34.94 ? 199 ASP B OD1 1 ATOM 5024 O OD2 . ASP B 1 226 ? -42.110 17.103 47.575 1.00 37.99 ? 199 ASP B OD2 1 ATOM 5025 N N . ILE B 1 227 ? -46.711 18.409 44.834 1.00 34.86 ? 200 ILE B N 1 ATOM 5026 C CA . ILE B 1 227 ? -47.771 19.365 44.466 1.00 37.92 ? 200 ILE B CA 1 ATOM 5027 C C . ILE B 1 227 ? -49.163 18.748 44.554 1.00 36.93 ? 200 ILE B C 1 ATOM 5028 O O . ILE B 1 227 ? -50.081 19.336 45.114 1.00 37.50 ? 200 ILE B O 1 ATOM 5029 C CB . ILE B 1 227 ? -47.578 19.933 43.048 1.00 40.78 ? 200 ILE B CB 1 ATOM 5030 C CG1 . ILE B 1 227 ? -46.492 20.989 43.055 1.00 46.40 ? 200 ILE B CG1 1 ATOM 5031 C CG2 . ILE B 1 227 ? -48.857 20.583 42.533 1.00 47.15 ? 200 ILE B CG2 1 ATOM 5032 C CD1 . ILE B 1 227 ? -46.158 21.557 41.686 1.00 49.72 ? 200 ILE B CD1 1 ATOM 5033 N N . ILE B 1 228 ? -49.316 17.563 43.987 1.00 33.75 ? 201 ILE B N 1 ATOM 5034 C CA . ILE B 1 228 ? -50.585 16.851 44.069 1.00 33.73 ? 201 ILE B CA 1 ATOM 5035 C C . ILE B 1 228 ? -50.970 16.617 45.543 1.00 35.76 ? 201 ILE B C 1 ATOM 5036 O O . ILE B 1 228 ? -52.081 16.908 45.948 1.00 35.70 ? 201 ILE B O 1 ATOM 5037 C CB . ILE B 1 228 ? -50.514 15.548 43.273 1.00 33.63 ? 201 ILE B CB 1 ATOM 5038 C CG1 . ILE B 1 228 ? -50.439 15.872 41.778 1.00 34.75 ? 201 ILE B CG1 1 ATOM 5039 C CG2 . ILE B 1 228 ? -51.713 14.652 43.558 1.00 34.14 ? 201 ILE B CG2 1 ATOM 5040 C CD1 . ILE B 1 228 ? -50.020 14.691 40.940 1.00 37.28 ? 201 ILE B CD1 1 ATOM 5041 N N . GLU B 1 229 ? -50.046 16.115 46.347 1.00 32.61 ? 202 GLU B N 1 ATOM 5042 C CA . GLU B 1 229 ? -50.297 15.933 47.774 1.00 34.87 ? 202 GLU B CA 1 ATOM 5043 C C . GLU B 1 229 ? -50.625 17.259 48.497 1.00 35.37 ? 202 GLU B C 1 ATOM 5044 O O . GLU B 1 229 ? -51.461 17.294 49.391 1.00 38.09 ? 202 GLU B O 1 ATOM 5045 C CB . GLU B 1 229 ? -49.083 15.263 48.410 1.00 36.62 ? 202 GLU B CB 1 ATOM 5046 C CG . GLU B 1 229 ? -49.184 15.001 49.894 1.00 38.03 ? 202 GLU B CG 1 ATOM 5047 C CD . GLU B 1 229 ? -47.894 14.446 50.468 1.00 41.45 ? 202 GLU B CD 1 ATOM 5048 O OE1 . GLU B 1 229 ? -47.937 13.800 51.528 1.00 45.39 ? 202 GLU B OE1 1 ATOM 5049 O OE2 . GLU B 1 229 ? -46.822 14.657 49.867 1.00 45.53 ? 202 GLU B OE2 1 ATOM 5050 N N . TYR B 1 230 ? -49.978 18.341 48.097 1.00 36.43 ? 203 TYR B N 1 ATOM 5051 C CA . TYR B 1 230 ? -50.217 19.677 48.653 1.00 38.68 ? 203 TYR B CA 1 ATOM 5052 C C . TYR B 1 230 ? -51.657 20.145 48.501 1.00 38.68 ? 203 TYR B C 1 ATOM 5053 O O . TYR B 1 230 ? -52.249 20.688 49.449 1.00 36.91 ? 203 TYR B O 1 ATOM 5054 C CB . TYR B 1 230 ? -49.298 20.669 47.962 1.00 39.51 ? 203 TYR B CB 1 ATOM 5055 C CG . TYR B 1 230 ? -49.401 22.091 48.437 1.00 40.20 ? 203 TYR B CG 1 ATOM 5056 C CD1 . TYR B 1 230 ? -48.670 22.529 49.536 1.00 40.71 ? 203 TYR B CD1 1 ATOM 5057 C CD2 . TYR B 1 230 ? -50.199 23.008 47.762 1.00 40.88 ? 203 TYR B CD2 1 ATOM 5058 C CE1 . TYR B 1 230 ? -48.757 23.830 49.971 1.00 40.19 ? 203 TYR B CE1 1 ATOM 5059 C CE2 . TYR B 1 230 ? -50.275 24.310 48.180 1.00 40.15 ? 203 TYR B CE2 1 ATOM 5060 C CZ . TYR B 1 230 ? -49.554 24.714 49.288 1.00 42.07 ? 203 TYR B CZ 1 ATOM 5061 O OH . TYR B 1 230 ? -49.622 26.028 49.698 1.00 40.38 ? 203 TYR B OH 1 ATOM 5062 N N . PHE B 1 231 ? -52.212 19.932 47.311 1.00 36.00 ? 204 PHE B N 1 ATOM 5063 C CA . PHE B 1 231 ? -53.602 20.267 47.074 1.00 37.40 ? 204 PHE B CA 1 ATOM 5064 C C . PHE B 1 231 ? -54.568 19.209 47.565 1.00 37.34 ? 204 PHE B C 1 ATOM 5065 O O . PHE B 1 231 ? -55.749 19.322 47.333 1.00 35.74 ? 204 PHE B O 1 ATOM 5066 C CB . PHE B 1 231 ? -53.838 20.584 45.602 1.00 36.29 ? 204 PHE B CB 1 ATOM 5067 C CG . PHE B 1 231 ? -53.277 21.904 45.197 1.00 36.45 ? 204 PHE B CG 1 ATOM 5068 C CD1 . PHE B 1 231 ? -53.923 23.081 45.570 1.00 36.48 ? 204 PHE B CD1 1 ATOM 5069 C CD2 . PHE B 1 231 ? -52.090 21.989 44.475 1.00 36.27 ? 204 PHE B CD2 1 ATOM 5070 C CE1 . PHE B 1 231 ? -53.416 24.313 45.218 1.00 35.80 ? 204 PHE B CE1 1 ATOM 5071 C CE2 . PHE B 1 231 ? -51.573 23.227 44.116 1.00 34.71 ? 204 PHE B CE2 1 ATOM 5072 C CZ . PHE B 1 231 ? -52.233 24.389 44.499 1.00 35.54 ? 204 PHE B CZ 1 ATOM 5073 N N . ARG B 1 232 ? -54.062 18.183 48.244 1.00 38.98 ? 205 ARG B N 1 ATOM 5074 C CA . ARG B 1 232 ? -54.879 17.090 48.751 1.00 38.06 ? 205 ARG B CA 1 ATOM 5075 C C . ARG B 1 232 ? -55.595 16.404 47.623 1.00 36.41 ? 205 ARG B C 1 ATOM 5076 O O . ARG B 1 232 ? -56.656 15.854 47.841 1.00 37.68 ? 205 ARG B O 1 ATOM 5077 C CB . ARG B 1 232 ? -55.951 17.555 49.755 1.00 37.97 ? 205 ARG B CB 1 ATOM 5078 C CG . ARG B 1 232 ? -55.562 18.636 50.759 1.00 38.04 ? 205 ARG B CG 1 ATOM 5079 C CD . ARG B 1 232 ? -54.376 18.312 51.606 1.00 38.83 ? 205 ARG B CD 1 ATOM 5080 N NE . ARG B 1 232 ? -54.101 19.398 52.542 1.00 42.47 ? 205 ARG B NE 1 ATOM 5081 C CZ . ARG B 1 232 ? -53.320 19.312 53.622 1.00 43.74 ? 205 ARG B CZ 1 ATOM 5082 N NH1 . ARG B 1 232 ? -52.759 18.162 53.963 1.00 43.46 ? 205 ARG B NH1 1 ATOM 5083 N NH2 . ARG B 1 232 ? -53.111 20.383 54.378 1.00 41.57 ? 205 ARG B NH2 1 ATOM 5084 N N . TRP B 1 233 ? -55.043 16.429 46.416 1.00 37.06 ? 206 TRP B N 1 ATOM 5085 C CA . TRP B 1 233 ? -55.622 15.653 45.335 1.00 36.34 ? 206 TRP B CA 1 ATOM 5086 C C . TRP B 1 233 ? -55.237 14.197 45.548 1.00 35.62 ? 206 TRP B C 1 ATOM 5087 O O . TRP B 1 233 ? -54.264 13.908 46.234 1.00 37.75 ? 206 TRP B O 1 ATOM 5088 C CB . TRP B 1 233 ? -55.140 16.136 43.981 1.00 36.85 ? 206 TRP B CB 1 ATOM 5089 C CG . TRP B 1 233 ? -55.521 17.529 43.684 1.00 38.56 ? 206 TRP B CG 1 ATOM 5090 C CD1 . TRP B 1 233 ? -56.609 18.203 44.158 1.00 38.86 ? 206 TRP B CD1 1 ATOM 5091 C CD2 . TRP B 1 233 ? -54.838 18.435 42.808 1.00 35.55 ? 206 TRP B CD2 1 ATOM 5092 N NE1 . TRP B 1 233 ? -56.639 19.467 43.646 1.00 37.40 ? 206 TRP B NE1 1 ATOM 5093 C CE2 . TRP B 1 233 ? -55.566 19.639 42.817 1.00 34.28 ? 206 TRP B CE2 1 ATOM 5094 C CE3 . TRP B 1 233 ? -53.674 18.353 42.030 1.00 32.28 ? 206 TRP B CE3 1 ATOM 5095 C CZ2 . TRP B 1 233 ? -55.180 20.746 42.080 1.00 34.14 ? 206 TRP B CZ2 1 ATOM 5096 C CZ3 . TRP B 1 233 ? -53.301 19.458 41.295 1.00 32.75 ? 206 TRP B CZ3 1 ATOM 5097 C CH2 . TRP B 1 233 ? -54.044 20.638 41.335 1.00 33.07 ? 206 TRP B CH2 1 ATOM 5098 N N . ASN B 1 234 ? -56.003 13.283 44.985 1.00 33.97 ? 207 ASN B N 1 ATOM 5099 C CA . ASN B 1 234 ? -55.685 11.868 45.138 1.00 38.17 ? 207 ASN B CA 1 ATOM 5100 C C . ASN B 1 234 ? -55.950 11.057 43.894 1.00 36.48 ? 207 ASN B C 1 ATOM 5101 O O . ASN B 1 234 ? -55.928 9.839 43.937 1.00 35.80 ? 207 ASN B O 1 ATOM 5102 C CB . ASN B 1 234 ? -56.516 11.271 46.288 1.00 40.51 ? 207 ASN B CB 1 ATOM 5103 C CG . ASN B 1 234 ? -57.986 11.230 45.957 1.00 40.14 ? 207 ASN B CG 1 ATOM 5104 O OD1 . ASN B 1 234 ? -58.385 11.478 44.825 1.00 38.59 ? 207 ASN B OD1 1 ATOM 5105 N ND2 . ASN B 1 234 ? -58.806 10.940 46.949 1.00 47.24 ? 207 ASN B ND2 1 ATOM 5106 N N . TRP B 1 235 ? -56.208 11.729 42.785 1.00 36.96 ? 208 TRP B N 1 ATOM 5107 C CA . TRP B 1 235 ? -56.693 11.051 41.609 1.00 39.20 ? 208 TRP B CA 1 ATOM 5108 C C . TRP B 1 235 ? -56.132 11.740 40.395 1.00 38.01 ? 208 TRP B C 1 ATOM 5109 O O . TRP B 1 235 ? -56.455 12.908 40.163 1.00 37.34 ? 208 TRP B O 1 ATOM 5110 C CB . TRP B 1 235 ? -58.208 11.159 41.634 1.00 41.86 ? 208 TRP B CB 1 ATOM 5111 C CG . TRP B 1 235 ? -58.992 10.480 40.578 1.00 40.88 ? 208 TRP B CG 1 ATOM 5112 C CD1 . TRP B 1 235 ? -59.864 11.071 39.696 1.00 41.08 ? 208 TRP B CD1 1 ATOM 5113 C CD2 . TRP B 1 235 ? -59.073 9.076 40.346 1.00 40.71 ? 208 TRP B CD2 1 ATOM 5114 N NE1 . TRP B 1 235 ? -60.471 10.114 38.924 1.00 40.82 ? 208 TRP B NE1 1 ATOM 5115 C CE2 . TRP B 1 235 ? -60.003 8.880 39.293 1.00 40.13 ? 208 TRP B CE2 1 ATOM 5116 C CE3 . TRP B 1 235 ? -58.459 7.957 40.925 1.00 43.48 ? 208 TRP B CE3 1 ATOM 5117 C CZ2 . TRP B 1 235 ? -60.325 7.610 38.802 1.00 41.19 ? 208 TRP B CZ2 1 ATOM 5118 C CZ3 . TRP B 1 235 ? -58.779 6.687 40.432 1.00 41.75 ? 208 TRP B CZ3 1 ATOM 5119 C CH2 . TRP B 1 235 ? -59.707 6.528 39.384 1.00 40.12 ? 208 TRP B CH2 1 ATOM 5120 N N . VAL B 1 236 ? -55.216 11.076 39.683 1.00 36.34 ? 209 VAL B N 1 ATOM 5121 C CA . VAL B 1 236 ? -54.675 11.646 38.459 1.00 35.25 ? 209 VAL B CA 1 ATOM 5122 C C . VAL B 1 236 ? -54.485 10.687 37.297 1.00 33.11 ? 209 VAL B C 1 ATOM 5123 O O . VAL B 1 236 ? -54.492 9.476 37.454 1.00 36.56 ? 209 VAL B O 1 ATOM 5124 C CB . VAL B 1 236 ? -53.308 12.295 38.784 1.00 34.29 ? 209 VAL B CB 1 ATOM 5125 C CG1 . VAL B 1 236 ? -53.408 13.125 40.038 1.00 34.00 ? 209 VAL B CG1 1 ATOM 5126 C CG2 . VAL B 1 236 ? -52.219 11.243 38.983 1.00 34.16 ? 209 VAL B CG2 1 ATOM 5127 N N . GLY B 1 237 ? -54.249 11.268 36.127 1.00 32.49 ? 210 GLY B N 1 ATOM 5128 C CA . GLY B 1 237 ? -53.787 10.535 34.938 1.00 30.87 ? 210 GLY B CA 1 ATOM 5129 C C . GLY B 1 237 ? -52.336 10.917 34.634 1.00 31.44 ? 210 GLY B C 1 ATOM 5130 O O . GLY B 1 237 ? -51.880 11.996 35.052 1.00 30.69 ? 210 GLY B O 1 ATOM 5131 N N . THR B 1 238 ? -51.616 10.057 33.900 1.00 28.68 ? 211 THR B N 1 ATOM 5132 C CA . THR B 1 238 ? -50.261 10.370 33.441 1.00 29.66 ? 211 THR B CA 1 ATOM 5133 C C . THR B 1 238 ? -50.081 10.138 31.947 1.00 29.14 ? 211 THR B C 1 ATOM 5134 O O . THR B 1 238 ? -50.633 9.194 31.350 1.00 28.05 ? 211 THR B O 1 ATOM 5135 C CB . THR B 1 238 ? -49.144 9.570 34.165 1.00 31.00 ? 211 THR B CB 1 ATOM 5136 O OG1 . THR B 1 238 ? -49.259 8.175 33.858 1.00 32.85 ? 211 THR B OG1 1 ATOM 5137 C CG2 . THR B 1 238 ? -49.206 9.775 35.653 1.00 32.66 ? 211 THR B CG2 1 ATOM 5138 N N . ILE B 1 239 ? -49.279 11.010 31.353 1.00 29.47 ? 212 ILE B N 1 ATOM 5139 C CA . ILE B 1 239 ? -48.873 10.895 29.954 1.00 29.06 ? 212 ILE B CA 1 ATOM 5140 C C . ILE B 1 239 ? -47.389 11.208 29.879 1.00 29.00 ? 212 ILE B C 1 ATOM 5141 O O . ILE B 1 239 ? -46.905 12.138 30.525 1.00 27.91 ? 212 ILE B O 1 ATOM 5142 C CB . ILE B 1 239 ? -49.642 11.867 29.089 1.00 31.47 ? 212 ILE B CB 1 ATOM 5143 C CG1 . ILE B 1 239 ? -51.132 11.517 29.152 1.00 33.96 ? 212 ILE B CG1 1 ATOM 5144 C CG2 . ILE B 1 239 ? -49.138 11.811 27.651 1.00 32.85 ? 212 ILE B CG2 1 ATOM 5145 C CD1 . ILE B 1 239 ? -52.011 12.552 28.527 1.00 36.33 ? 212 ILE B CD1 1 ATOM 5146 N N . ALA B 1 240 ? -46.645 10.408 29.119 1.00 29.09 ? 213 ALA B N 1 ATOM 5147 C CA . ALA B 1 240 ? -45.201 10.602 28.993 1.00 28.95 ? 213 ALA B CA 1 ATOM 5148 C C . ALA B 1 240 ? -44.777 10.401 27.553 1.00 29.01 ? 213 ALA B C 1 ATOM 5149 O O . ALA B 1 240 ? -45.306 9.531 26.860 1.00 28.54 ? 213 ALA B O 1 ATOM 5150 C CB . ALA B 1 240 ? -44.460 9.616 29.879 1.00 29.05 ? 213 ALA B CB 1 ATOM 5151 N N . ALA B 1 241 ? -43.767 11.165 27.139 1.00 28.57 ? 214 ALA B N 1 ATOM 5152 C CA . ALA B 1 241 ? -43.102 10.937 25.885 1.00 26.47 ? 214 ALA B CA 1 ATOM 5153 C C . ALA B 1 241 ? -42.391 9.609 25.957 1.00 27.86 ? 214 ALA B C 1 ATOM 5154 O O . ALA B 1 241 ? -41.723 9.282 26.965 1.00 28.60 ? 214 ALA B O 1 ATOM 5155 C CB . ALA B 1 241 ? -42.111 12.032 25.600 1.00 25.74 ? 214 ALA B CB 1 ATOM 5156 N N . ASP B 1 242 ? -42.514 8.846 24.890 1.00 27.34 ? 215 ASP B N 1 ATOM 5157 C CA . ASP B 1 242 ? -41.926 7.530 24.834 1.00 28.18 ? 215 ASP B CA 1 ATOM 5158 C C . ASP B 1 242 ? -40.452 7.643 24.467 1.00 27.31 ? 215 ASP B C 1 ATOM 5159 O O . ASP B 1 242 ? -40.053 7.261 23.389 1.00 25.47 ? 215 ASP B O 1 ATOM 5160 C CB . ASP B 1 242 ? -42.695 6.681 23.818 1.00 30.22 ? 215 ASP B CB 1 ATOM 5161 C CG . ASP B 1 242 ? -42.364 5.215 23.907 1.00 32.30 ? 215 ASP B CG 1 ATOM 5162 O OD1 . ASP B 1 242 ? -41.743 4.761 24.900 1.00 33.25 ? 215 ASP B OD1 1 ATOM 5163 O OD2 . ASP B 1 242 ? -42.752 4.493 22.980 1.00 35.23 ? 215 ASP B OD2 1 ATOM 5164 N N . ASP B 1 243 ? -39.643 8.145 25.392 1.00 25.96 ? 216 ASP B N 1 ATOM 5165 C CA . ASP B 1 243 ? -38.213 8.312 25.182 1.00 27.38 ? 216 ASP B CA 1 ATOM 5166 C C . ASP B 1 243 ? -37.488 8.313 26.555 1.00 27.14 ? 216 ASP B C 1 ATOM 5167 O O . ASP B 1 243 ? -38.112 8.084 27.583 1.00 25.01 ? 216 ASP B O 1 ATOM 5168 C CB . ASP B 1 243 ? -37.940 9.596 24.367 1.00 27.47 ? 216 ASP B CB 1 ATOM 5169 C CG . ASP B 1 243 ? -38.385 10.879 25.115 1.00 32.26 ? 216 ASP B CG 1 ATOM 5170 O OD1 . ASP B 1 243 ? -38.422 10.903 26.370 1.00 30.55 ? 216 ASP B OD1 1 ATOM 5171 O OD2 . ASP B 1 243 ? -38.714 11.871 24.443 1.00 35.34 ? 216 ASP B OD2 1 ATOM 5172 N N . ASP B 1 244 ? -36.191 8.593 26.559 1.00 28.12 ? 217 ASP B N 1 ATOM 5173 C CA . ASP B 1 244 ? -35.380 8.567 27.783 1.00 30.06 ? 217 ASP B CA 1 ATOM 5174 C C . ASP B 1 244 ? -35.578 9.765 28.697 1.00 28.49 ? 217 ASP B C 1 ATOM 5175 O O . ASP B 1 244 ? -34.952 9.823 29.770 1.00 26.74 ? 217 ASP B O 1 ATOM 5176 C CB . ASP B 1 244 ? -33.890 8.468 27.437 1.00 34.89 ? 217 ASP B CB 1 ATOM 5177 C CG . ASP B 1 244 ? -33.481 7.058 27.008 1.00 39.39 ? 217 ASP B CG 1 ATOM 5178 O OD1 . ASP B 1 244 ? -34.183 6.088 27.368 1.00 41.93 ? 217 ASP B OD1 1 ATOM 5179 O OD2 . ASP B 1 244 ? -32.453 6.935 26.312 1.00 51.18 ? 217 ASP B OD2 1 ATOM 5180 N N . TYR B 1 245 ? -36.429 10.711 28.290 1.00 26.14 ? 218 TYR B N 1 ATOM 5181 C CA . TYR B 1 245 ? -36.842 11.790 29.159 1.00 24.09 ? 218 TYR B CA 1 ATOM 5182 C C . TYR B 1 245 ? -38.181 11.420 29.828 1.00 24.91 ? 218 TYR B C 1 ATOM 5183 O O . TYR B 1 245 ? -38.273 11.315 31.046 1.00 23.62 ? 218 TYR B O 1 ATOM 5184 C CB . TYR B 1 245 ? -36.937 13.096 28.377 1.00 25.41 ? 218 TYR B CB 1 ATOM 5185 C CG . TYR B 1 245 ? -37.601 14.267 29.102 1.00 24.02 ? 218 TYR B CG 1 ATOM 5186 C CD1 . TYR B 1 245 ? -37.013 14.831 30.199 1.00 24.34 ? 218 TYR B CD1 1 ATOM 5187 C CD2 . TYR B 1 245 ? -38.821 14.803 28.641 1.00 24.46 ? 218 TYR B CD2 1 ATOM 5188 C CE1 . TYR B 1 245 ? -37.605 15.900 30.856 1.00 24.83 ? 218 TYR B CE1 1 ATOM 5189 C CE2 . TYR B 1 245 ? -39.420 15.890 29.264 1.00 25.08 ? 218 TYR B CE2 1 ATOM 5190 C CZ . TYR B 1 245 ? -38.806 16.423 30.379 1.00 27.04 ? 218 TYR B CZ 1 ATOM 5191 O OH . TYR B 1 245 ? -39.378 17.470 31.014 1.00 28.41 ? 218 TYR B OH 1 ATOM 5192 N N . GLY B 1 246 ? -39.192 11.156 29.025 1.00 25.10 ? 219 GLY B N 1 ATOM 5193 C CA . GLY B 1 246 ? -40.536 10.872 29.506 1.00 24.36 ? 219 GLY B CA 1 ATOM 5194 C C . GLY B 1 246 ? -40.681 9.629 30.342 1.00 25.25 ? 219 GLY B C 1 ATOM 5195 O O . GLY B 1 246 ? -41.334 9.683 31.386 1.00 25.88 ? 219 GLY B O 1 ATOM 5196 N N . ARG B 1 247 ? -40.095 8.503 29.908 1.00 24.98 ? 220 ARG B N 1 ATOM 5197 C CA . ARG B 1 247 ? -40.304 7.242 30.596 1.00 25.72 ? 220 ARG B CA 1 ATOM 5198 C C . ARG B 1 247 ? -39.686 7.193 31.997 1.00 27.01 ? 220 ARG B C 1 ATOM 5199 O O . ARG B 1 247 ? -40.375 6.795 32.939 1.00 26.82 ? 220 ARG B O 1 ATOM 5200 C CB . ARG B 1 247 ? -39.834 6.038 29.779 1.00 26.36 ? 220 ARG B CB 1 ATOM 5201 C CG . ARG B 1 247 ? -40.663 5.784 28.538 1.00 28.36 ? 220 ARG B CG 1 ATOM 5202 C CD . ARG B 1 247 ? -40.205 4.533 27.787 1.00 29.23 ? 220 ARG B CD 1 ATOM 5203 N NE . ARG B 1 247 ? -38.773 4.555 27.487 1.00 29.95 ? 220 ARG B NE 1 ATOM 5204 C CZ . ARG B 1 247 ? -38.230 4.739 26.285 1.00 29.50 ? 220 ARG B CZ 1 ATOM 5205 N NH1 . ARG B 1 247 ? -38.967 4.913 25.213 1.00 28.83 ? 220 ARG B NH1 1 ATOM 5206 N NH2 . ARG B 1 247 ? -36.917 4.728 26.163 1.00 31.03 ? 220 ARG B NH2 1 ATOM 5207 N N . PRO B 1 248 ? -38.405 7.584 32.140 1.00 27.10 ? 221 PRO B N 1 ATOM 5208 C CA . PRO B 1 248 ? -37.857 7.556 33.514 1.00 26.19 ? 221 PRO B CA 1 ATOM 5209 C C . PRO B 1 248 ? -38.436 8.639 34.414 1.00 26.18 ? 221 PRO B C 1 ATOM 5210 O O . PRO B 1 248 ? -38.510 8.430 35.614 1.00 26.71 ? 221 PRO B O 1 ATOM 5211 C CB . PRO B 1 248 ? -36.344 7.750 33.326 1.00 26.65 ? 221 PRO B CB 1 ATOM 5212 C CG . PRO B 1 248 ? -36.072 7.789 31.845 1.00 28.06 ? 221 PRO B CG 1 ATOM 5213 C CD . PRO B 1 248 ? -37.388 7.952 31.129 1.00 27.18 ? 221 PRO B CD 1 ATOM 5214 N N . GLY B 1 249 ? -38.854 9.777 33.859 1.00 26.26 ? 222 GLY B N 1 ATOM 5215 C CA . GLY B 1 249 ? -39.516 10.831 34.647 1.00 26.62 ? 222 GLY B CA 1 ATOM 5216 C C . GLY B 1 249 ? -40.843 10.342 35.225 1.00 26.64 ? 222 GLY B C 1 ATOM 5217 O O . GLY B 1 249 ? -41.110 10.484 36.408 1.00 25.80 ? 222 GLY B O 1 ATOM 5218 N N . ILE B 1 250 ? -41.673 9.739 34.380 1.00 26.87 ? 223 ILE B N 1 ATOM 5219 C CA . ILE B 1 250 ? -42.982 9.289 34.818 1.00 29.41 ? 223 ILE B CA 1 ATOM 5220 C C . ILE B 1 250 ? -42.892 8.062 35.711 1.00 29.50 ? 223 ILE B C 1 ATOM 5221 O O . ILE B 1 250 ? -43.715 7.915 36.610 1.00 28.81 ? 223 ILE B O 1 ATOM 5222 C CB . ILE B 1 250 ? -43.974 9.102 33.649 1.00 30.78 ? 223 ILE B CB 1 ATOM 5223 C CG1 . ILE B 1 250 ? -45.397 9.477 34.102 1.00 32.59 ? 223 ILE B CG1 1 ATOM 5224 C CG2 . ILE B 1 250 ? -43.911 7.698 33.064 1.00 31.97 ? 223 ILE B CG2 1 ATOM 5225 C CD1 . ILE B 1 250 ? -45.603 10.972 34.326 1.00 32.11 ? 223 ILE B CD1 1 ATOM 5226 N N . GLU B 1 251 ? -41.883 7.213 35.507 1.00 29.01 ? 224 GLU B N 1 ATOM 5227 C CA . GLU B 1 251 ? -41.697 6.065 36.391 1.00 28.68 ? 224 GLU B CA 1 ATOM 5228 C C . GLU B 1 251 ? -41.359 6.491 37.824 1.00 28.53 ? 224 GLU B C 1 ATOM 5229 O O . GLU B 1 251 ? -41.848 5.890 38.789 1.00 29.00 ? 224 GLU B O 1 ATOM 5230 C CB . GLU B 1 251 ? -40.636 5.117 35.836 1.00 32.00 ? 224 GLU B CB 1 ATOM 5231 C CG . GLU B 1 251 ? -40.211 4.024 36.804 1.00 33.93 ? 224 GLU B CG 1 ATOM 5232 C CD . GLU B 1 251 ? -41.351 3.090 37.279 1.00 36.43 ? 224 GLU B CD 1 ATOM 5233 O OE1 . GLU B 1 251 ? -41.093 2.286 38.204 1.00 41.41 ? 224 GLU B OE1 1 ATOM 5234 O OE2 . GLU B 1 251 ? -42.492 3.122 36.748 1.00 36.91 ? 224 GLU B OE2 1 ATOM 5235 N N . LYS B 1 252 ? -40.526 7.514 37.959 1.00 26.72 ? 225 LYS B N 1 ATOM 5236 C CA . LYS B 1 252 ? -40.215 8.069 39.268 1.00 26.79 ? 225 LYS B CA 1 ATOM 5237 C C . LYS B 1 252 ? -41.434 8.753 39.869 1.00 27.11 ? 225 LYS B C 1 ATOM 5238 O O . LYS B 1 252 ? -41.720 8.624 41.062 1.00 28.60 ? 225 LYS B O 1 ATOM 5239 C CB . LYS B 1 252 ? -39.075 9.071 39.149 1.00 27.01 ? 225 LYS B CB 1 ATOM 5240 C CG . LYS B 1 252 ? -38.706 9.774 40.444 1.00 27.92 ? 225 LYS B CG 1 ATOM 5241 C CD . LYS B 1 252 ? -38.327 8.792 41.561 1.00 27.73 ? 225 LYS B CD 1 ATOM 5242 C CE . LYS B 1 252 ? -37.691 9.580 42.710 1.00 30.32 ? 225 LYS B CE 1 ATOM 5243 N NZ . LYS B 1 252 ? -37.481 8.715 43.886 1.00 32.51 ? 225 LYS B NZ 1 ATOM 5244 N N . PHE B 1 253 ? -42.182 9.455 39.034 1.00 27.71 ? 226 PHE B N 1 ATOM 5245 C CA . PHE B 1 253 ? -43.428 10.044 39.498 1.00 27.86 ? 226 PHE B CA 1 ATOM 5246 C C . PHE B 1 253 ? -44.386 9.002 40.046 1.00 27.54 ? 226 PHE B C 1 ATOM 5247 O O . PHE B 1 253 ? -45.013 9.213 41.101 1.00 29.23 ? 226 PHE B O 1 ATOM 5248 C CB . PHE B 1 253 ? -44.146 10.836 38.412 1.00 26.94 ? 226 PHE B CB 1 ATOM 5249 C CG . PHE B 1 253 ? -45.514 11.288 38.836 1.00 27.77 ? 226 PHE B CG 1 ATOM 5250 C CD1 . PHE B 1 253 ? -45.663 12.313 39.772 1.00 28.86 ? 226 PHE B CD1 1 ATOM 5251 C CD2 . PHE B 1 253 ? -46.646 10.642 38.381 1.00 28.55 ? 226 PHE B CD2 1 ATOM 5252 C CE1 . PHE B 1 253 ? -46.921 12.706 40.206 1.00 29.18 ? 226 PHE B CE1 1 ATOM 5253 C CE2 . PHE B 1 253 ? -47.914 11.035 38.808 1.00 31.20 ? 226 PHE B CE2 1 ATOM 5254 C CZ . PHE B 1 253 ? -48.049 12.077 39.718 1.00 30.89 ? 226 PHE B CZ 1 ATOM 5255 N N . ARG B 1 254 ? -44.513 7.891 39.335 1.00 28.54 ? 227 ARG B N 1 ATOM 5256 C CA . ARG B 1 254 ? -45.401 6.811 39.748 1.00 29.78 ? 227 ARG B CA 1 ATOM 5257 C C . ARG B 1 254 ? -45.027 6.314 41.129 1.00 31.21 ? 227 ARG B C 1 ATOM 5258 O O . ARG B 1 254 ? -45.881 6.151 41.982 1.00 31.86 ? 227 ARG B O 1 ATOM 5259 C CB . ARG B 1 254 ? -45.374 5.643 38.740 1.00 29.98 ? 227 ARG B CB 1 ATOM 5260 C CG . ARG B 1 254 ? -46.327 4.479 39.078 1.00 31.08 ? 227 ARG B CG 1 ATOM 5261 C CD . ARG B 1 254 ? -45.941 3.138 38.419 1.00 32.08 ? 227 ARG B CD 1 ATOM 5262 N NE . ARG B 1 254 ? -44.573 2.778 38.780 1.00 32.62 ? 227 ARG B NE 1 ATOM 5263 C CZ . ARG B 1 254 ? -44.174 2.396 39.999 1.00 36.45 ? 227 ARG B CZ 1 ATOM 5264 N NH1 . ARG B 1 254 ? -45.042 2.246 41.005 1.00 34.65 ? 227 ARG B NH1 1 ATOM 5265 N NH2 . ARG B 1 254 ? -42.889 2.149 40.225 1.00 35.80 ? 227 ARG B NH2 1 ATOM 5266 N N . GLU B 1 255 ? -43.743 6.086 41.340 1.00 31.49 ? 228 GLU B N 1 ATOM 5267 C CA . GLU B 1 255 ? -43.247 5.603 42.619 1.00 34.59 ? 228 GLU B CA 1 ATOM 5268 C C . GLU B 1 255 ? -43.582 6.592 43.753 1.00 34.71 ? 228 GLU B C 1 ATOM 5269 O O . GLU B 1 255 ? -44.043 6.195 44.814 1.00 33.09 ? 228 GLU B O 1 ATOM 5270 C CB . GLU B 1 255 ? -41.728 5.367 42.521 1.00 35.84 ? 228 GLU B CB 1 ATOM 5271 C CG . GLU B 1 255 ? -41.053 4.932 43.801 1.00 44.10 ? 228 GLU B CG 1 ATOM 5272 C CD . GLU B 1 255 ? -39.527 5.020 43.734 1.00 49.86 ? 228 GLU B CD 1 ATOM 5273 O OE1 . GLU B 1 255 ? -38.955 4.932 42.628 1.00 59.21 ? 228 GLU B OE1 1 ATOM 5274 O OE2 . GLU B 1 255 ? -38.887 5.174 44.795 1.00 59.09 ? 228 GLU B OE2 1 ATOM 5275 N N . GLU B 1 256 ? -43.309 7.869 43.534 1.00 33.57 ? 229 GLU B N 1 ATOM 5276 C CA . GLU B 1 256 ? -43.539 8.871 44.549 1.00 33.71 ? 229 GLU B CA 1 ATOM 5277 C C . GLU B 1 256 ? -45.039 9.074 44.774 1.00 34.30 ? 229 GLU B C 1 ATOM 5278 O O . GLU B 1 256 ? -45.474 9.308 45.898 1.00 30.68 ? 229 GLU B O 1 ATOM 5279 C CB . GLU B 1 256 ? -42.844 10.184 44.175 1.00 34.18 ? 229 GLU B CB 1 ATOM 5280 C CG . GLU B 1 256 ? -41.318 10.061 44.144 1.00 38.15 ? 229 GLU B CG 1 ATOM 5281 C CD . GLU B 1 256 ? -40.734 9.651 45.485 1.00 40.56 ? 229 GLU B CD 1 ATOM 5282 O OE1 . GLU B 1 256 ? -41.260 10.115 46.520 1.00 43.44 ? 229 GLU B OE1 1 ATOM 5283 O OE2 . GLU B 1 256 ? -39.759 8.864 45.509 1.00 40.32 ? 229 GLU B OE2 1 ATOM 5284 N N . ALA B 1 257 ? -45.821 8.945 43.714 1.00 33.61 ? 230 ALA B N 1 ATOM 5285 C CA . ALA B 1 257 ? -47.257 9.072 43.851 1.00 37.05 ? 230 ALA B CA 1 ATOM 5286 C C . ALA B 1 257 ? -47.832 7.937 44.699 1.00 38.68 ? 230 ALA B C 1 ATOM 5287 O O . ALA B 1 257 ? -48.669 8.174 45.581 1.00 37.26 ? 230 ALA B O 1 ATOM 5288 C CB . ALA B 1 257 ? -47.916 9.092 42.498 1.00 36.22 ? 230 ALA B CB 1 ATOM 5289 N N . GLU B 1 258 ? -47.366 6.717 44.448 1.00 39.34 ? 231 GLU B N 1 ATOM 5290 C CA . GLU B 1 258 ? -47.809 5.575 45.231 1.00 44.20 ? 231 GLU B CA 1 ATOM 5291 C C . GLU B 1 258 ? -47.472 5.767 46.700 1.00 41.68 ? 231 GLU B C 1 ATOM 5292 O O . GLU B 1 258 ? -48.304 5.537 47.549 1.00 44.23 ? 231 GLU B O 1 ATOM 5293 C CB . GLU B 1 258 ? -47.234 4.273 44.688 1.00 46.26 ? 231 GLU B CB 1 ATOM 5294 C CG . GLU B 1 258 ? -47.938 3.928 43.382 1.00 51.87 ? 231 GLU B CG 1 ATOM 5295 C CD . GLU B 1 258 ? -47.504 2.633 42.715 1.00 54.28 ? 231 GLU B CD 1 ATOM 5296 O OE1 . GLU B 1 258 ? -46.838 1.781 43.377 1.00 52.39 ? 231 GLU B OE1 1 ATOM 5297 O OE2 . GLU B 1 258 ? -47.839 2.497 41.504 1.00 49.21 ? 231 GLU B OE2 1 ATOM 5298 N N . GLU B 1 259 ? -46.264 6.236 46.980 1.00 42.58 ? 232 GLU B N 1 ATOM 5299 C CA . GLU B 1 259 ? -45.829 6.531 48.346 1.00 44.71 ? 232 GLU B CA 1 ATOM 5300 C C . GLU B 1 259 ? -46.780 7.491 49.078 1.00 40.60 ? 232 GLU B C 1 ATOM 5301 O O . GLU B 1 259 ? -46.880 7.452 50.290 1.00 41.02 ? 232 GLU B O 1 ATOM 5302 C CB . GLU B 1 259 ? -44.422 7.156 48.334 1.00 49.95 ? 232 GLU B CB 1 ATOM 5303 C CG . GLU B 1 259 ? -43.615 6.842 49.574 1.00 61.33 ? 232 GLU B CG 1 ATOM 5304 C CD . GLU B 1 259 ? -43.257 5.375 49.677 1.00 69.82 ? 232 GLU B CD 1 ATOM 5305 O OE1 . GLU B 1 259 ? -43.153 4.894 50.821 1.00 83.20 ? 232 GLU B OE1 1 ATOM 5306 O OE2 . GLU B 1 259 ? -43.104 4.702 48.629 1.00 80.10 ? 232 GLU B OE2 1 ATOM 5307 N N . ARG B 1 260 ? -47.432 8.381 48.338 1.00 38.10 ? 233 ARG B N 1 ATOM 5308 C CA . ARG B 1 260 ? -48.304 9.392 48.933 1.00 36.98 ? 233 ARG B CA 1 ATOM 5309 C C . ARG B 1 260 ? -49.776 9.003 48.815 1.00 37.16 ? 233 ARG B C 1 ATOM 5310 O O . ARG B 1 260 ? -50.641 9.843 48.988 1.00 36.45 ? 233 ARG B O 1 ATOM 5311 C CB . ARG B 1 260 ? -48.042 10.750 48.262 1.00 34.36 ? 233 ARG B CB 1 ATOM 5312 C CG . ARG B 1 260 ? -46.638 11.276 48.524 1.00 34.24 ? 233 ARG B CG 1 ATOM 5313 C CD . ARG B 1 260 ? -46.222 12.296 47.474 1.00 34.30 ? 233 ARG B CD 1 ATOM 5314 N NE . ARG B 1 260 ? -44.945 12.945 47.777 1.00 32.06 ? 233 ARG B NE 1 ATOM 5315 C CZ . ARG B 1 260 ? -43.762 12.341 47.728 1.00 33.57 ? 233 ARG B CZ 1 ATOM 5316 N NH1 . ARG B 1 260 ? -43.654 11.061 47.399 1.00 32.87 ? 233 ARG B NH1 1 ATOM 5317 N NH2 . ARG B 1 260 ? -42.672 13.020 48.037 1.00 33.99 ? 233 ARG B NH2 1 ATOM 5318 N N . ASP B 1 261 ? -50.058 7.745 48.477 1.00 39.10 ? 234 ASP B N 1 ATOM 5319 C CA . ASP B 1 261 ? -51.437 7.282 48.224 1.00 42.31 ? 234 ASP B CA 1 ATOM 5320 C C . ASP B 1 261 ? -52.187 8.108 47.187 1.00 42.77 ? 234 ASP B C 1 ATOM 5321 O O . ASP B 1 261 ? -53.391 8.339 47.320 1.00 38.86 ? 234 ASP B O 1 ATOM 5322 C CB . ASP B 1 261 ? -52.229 7.203 49.534 1.00 46.13 ? 234 ASP B CB 1 ATOM 5323 C CG . ASP B 1 261 ? -51.533 6.323 50.568 1.00 49.56 ? 234 ASP B CG 1 ATOM 5324 O OD1 . ASP B 1 261 ? -51.066 5.229 50.204 1.00 51.04 ? 234 ASP B OD1 1 ATOM 5325 O OD2 . ASP B 1 261 ? -51.411 6.741 51.731 1.00 57.06 ? 234 ASP B OD2 1 ATOM 5326 N N . ILE B 1 262 ? -51.468 8.547 46.149 1.00 39.54 ? 235 ILE B N 1 ATOM 5327 C CA . ILE B 1 262 ? -52.085 9.164 44.988 1.00 36.66 ? 235 ILE B CA 1 ATOM 5328 C C . ILE B 1 262 ? -52.355 8.057 43.995 1.00 37.76 ? 235 ILE B C 1 ATOM 5329 O O . ILE B 1 262 ? -51.428 7.348 43.618 1.00 39.27 ? 235 ILE B O 1 ATOM 5330 C CB . ILE B 1 262 ? -51.161 10.216 44.358 1.00 36.05 ? 235 ILE B CB 1 ATOM 5331 C CG1 . ILE B 1 262 ? -50.932 11.361 45.349 1.00 36.12 ? 235 ILE B CG1 1 ATOM 5332 C CG2 . ILE B 1 262 ? -51.771 10.750 43.085 1.00 35.16 ? 235 ILE B CG2 1 ATOM 5333 C CD1 . ILE B 1 262 ? -49.758 12.235 45.016 1.00 35.14 ? 235 ILE B CD1 1 HETATM 5334 N N . CSO B 1 263 ? -53.622 7.893 43.609 1.00 38.38 ? 236 CSO B N 1 HETATM 5335 C CA . CSO B 1 263 ? -54.031 6.831 42.693 1.00 39.23 ? 236 CSO B CA 1 HETATM 5336 C CB . CSO B 1 263 ? -55.441 6.301 42.978 1.00 42.70 ? 236 CSO B CB 1 HETATM 5337 S SG . CSO B 1 263 ? -55.578 5.680 44.644 1.00 53.34 ? 236 CSO B SG 1 HETATM 5338 C C . CSO B 1 263 ? -53.959 7.377 41.304 1.00 37.01 ? 236 CSO B C 1 HETATM 5339 O O . CSO B 1 263 ? -54.299 8.548 41.069 1.00 37.35 ? 236 CSO B O 1 HETATM 5340 O OD . CSO B 1 263 ? -54.405 4.392 44.845 1.00 49.97 ? 236 CSO B OD 1 ATOM 5341 N N . ILE B 1 264 ? -53.477 6.542 40.386 1.00 32.77 ? 237 ILE B N 1 ATOM 5342 C CA . ILE B 1 264 ? -53.268 6.920 39.006 1.00 32.75 ? 237 ILE B CA 1 ATOM 5343 C C . ILE B 1 264 ? -54.215 6.092 38.152 1.00 32.96 ? 237 ILE B C 1 ATOM 5344 O O . ILE B 1 264 ? -54.143 4.867 38.112 1.00 32.54 ? 237 ILE B O 1 ATOM 5345 C CB . ILE B 1 264 ? -51.811 6.678 38.532 1.00 30.73 ? 237 ILE B CB 1 ATOM 5346 C CG1 . ILE B 1 264 ? -50.862 7.531 39.353 1.00 31.11 ? 237 ILE B CG1 1 ATOM 5347 C CG2 . ILE B 1 264 ? -51.685 6.967 37.034 1.00 29.96 ? 237 ILE B CG2 1 ATOM 5348 C CD1 . ILE B 1 264 ? -49.393 7.172 39.190 1.00 33.07 ? 237 ILE B CD1 1 ATOM 5349 N N . ASP B 1 265 ? -55.104 6.781 37.466 1.00 34.48 ? 238 ASP B N 1 ATOM 5350 C CA . ASP B 1 265 ? -56.187 6.125 36.776 1.00 35.10 ? 238 ASP B CA 1 ATOM 5351 C C . ASP B 1 265 ? -55.788 5.652 35.398 1.00 36.18 ? 238 ASP B C 1 ATOM 5352 O O . ASP B 1 265 ? -56.389 4.709 34.872 1.00 39.60 ? 238 ASP B O 1 ATOM 5353 C CB . ASP B 1 265 ? -57.381 7.069 36.647 1.00 36.10 ? 238 ASP B CB 1 ATOM 5354 C CG . ASP B 1 265 ? -58.616 6.367 36.061 1.00 38.32 ? 238 ASP B CG 1 ATOM 5355 O OD1 . ASP B 1 265 ? -58.960 5.272 36.548 1.00 37.37 ? 238 ASP B OD1 1 ATOM 5356 O OD2 . ASP B 1 265 ? -59.213 6.908 35.107 1.00 37.60 ? 238 ASP B OD2 1 ATOM 5357 N N . PHE B 1 266 ? -54.826 6.325 34.777 1.00 32.83 ? 239 PHE B N 1 ATOM 5358 C CA . PHE B 1 266 ? -54.297 5.837 33.513 1.00 31.95 ? 239 PHE B CA 1 ATOM 5359 C C . PHE B 1 266 ? -52.865 6.292 33.290 1.00 32.60 ? 239 PHE B C 1 ATOM 5360 O O . PHE B 1 266 ? -52.393 7.244 33.912 1.00 31.17 ? 239 PHE B O 1 ATOM 5361 C CB . PHE B 1 266 ? -55.181 6.272 32.339 1.00 31.37 ? 239 PHE B CB 1 ATOM 5362 C CG . PHE B 1 266 ? -55.262 7.772 32.136 1.00 31.08 ? 239 PHE B CG 1 ATOM 5363 C CD1 . PHE B 1 266 ? -54.269 8.447 31.449 1.00 31.21 ? 239 PHE B CD1 1 ATOM 5364 C CD2 . PHE B 1 266 ? -56.354 8.500 32.604 1.00 30.65 ? 239 PHE B CD2 1 ATOM 5365 C CE1 . PHE B 1 266 ? -54.328 9.818 31.262 1.00 29.72 ? 239 PHE B CE1 1 ATOM 5366 C CE2 . PHE B 1 266 ? -56.444 9.864 32.396 1.00 30.15 ? 239 PHE B CE2 1 ATOM 5367 C CZ . PHE B 1 266 ? -55.424 10.526 31.722 1.00 31.92 ? 239 PHE B CZ 1 ATOM 5368 N N . SER B 1 267 ? -52.171 5.596 32.405 1.00 31.13 ? 240 SER B N 1 ATOM 5369 C CA . SER B 1 267 ? -50.812 5.961 32.054 1.00 32.14 ? 240 SER B CA 1 ATOM 5370 C C . SER B 1 267 ? -50.551 5.618 30.587 1.00 33.42 ? 240 SER B C 1 ATOM 5371 O O . SER B 1 267 ? -50.579 4.458 30.190 1.00 33.62 ? 240 SER B O 1 ATOM 5372 C CB . SER B 1 267 ? -49.824 5.296 33.007 1.00 33.64 ? 240 SER B CB 1 ATOM 5373 O OG . SER B 1 267 ? -49.909 3.894 32.919 1.00 35.62 ? 240 SER B OG 1 ATOM 5374 N N . GLU B 1 268 ? -50.319 6.647 29.781 1.00 33.35 ? 241 GLU B N 1 ATOM 5375 C CA . GLU B 1 268 ? -50.190 6.497 28.344 1.00 31.59 ? 241 GLU B CA 1 ATOM 5376 C C . GLU B 1 268 ? -48.878 7.102 27.873 1.00 31.31 ? 241 GLU B C 1 ATOM 5377 O O . GLU B 1 268 ? -48.311 7.989 28.517 1.00 28.92 ? 241 GLU B O 1 ATOM 5378 C CB . GLU B 1 268 ? -51.386 7.174 27.635 1.00 33.24 ? 241 GLU B CB 1 ATOM 5379 C CG . GLU B 1 268 ? -52.760 6.555 27.967 1.00 34.50 ? 241 GLU B CG 1 ATOM 5380 C CD . GLU B 1 268 ? -52.864 5.073 27.605 1.00 34.50 ? 241 GLU B CD 1 ATOM 5381 O OE1 . GLU B 1 268 ? -53.510 4.308 28.337 1.00 36.62 ? 241 GLU B OE1 1 ATOM 5382 O OE2 . GLU B 1 268 ? -52.274 4.661 26.597 1.00 35.97 ? 241 GLU B OE2 1 ATOM 5383 N N . LEU B 1 269 ? -48.407 6.615 26.731 1.00 32.15 ? 242 LEU B N 1 ATOM 5384 C CA . LEU B 1 269 ? -47.189 7.121 26.095 1.00 33.12 ? 242 LEU B CA 1 ATOM 5385 C C . LEU B 1 269 ? -47.566 7.798 24.824 1.00 32.92 ? 242 LEU B C 1 ATOM 5386 O O . LEU B 1 269 ? -48.510 7.380 24.167 1.00 33.08 ? 242 LEU B O 1 ATOM 5387 C CB . LEU B 1 269 ? -46.223 5.988 25.767 1.00 33.82 ? 242 LEU B CB 1 ATOM 5388 C CG . LEU B 1 269 ? -45.760 5.230 27.012 1.00 35.76 ? 242 LEU B CG 1 ATOM 5389 C CD1 . LEU B 1 269 ? -45.036 3.975 26.586 1.00 37.35 ? 242 LEU B CD1 1 ATOM 5390 C CD2 . LEU B 1 269 ? -44.880 6.089 27.889 1.00 35.38 ? 242 LEU B CD2 1 ATOM 5391 N N . ILE B 1 270 ? -46.816 8.831 24.473 1.00 33.42 ? 243 ILE B N 1 ATOM 5392 C CA . ILE B 1 270 ? -47.000 9.549 23.215 1.00 35.61 ? 243 ILE B CA 1 ATOM 5393 C C . ILE B 1 270 ? -45.658 9.901 22.614 1.00 34.48 ? 243 ILE B C 1 ATOM 5394 O O . ILE B 1 270 ? -44.627 9.887 23.306 1.00 29.40 ? 243 ILE B O 1 ATOM 5395 C CB . ILE B 1 270 ? -47.713 10.905 23.418 1.00 40.42 ? 243 ILE B CB 1 ATOM 5396 C CG1 . ILE B 1 270 ? -46.962 11.755 24.445 1.00 43.04 ? 243 ILE B CG1 1 ATOM 5397 C CG2 . ILE B 1 270 ? -49.150 10.674 23.829 1.00 45.95 ? 243 ILE B CG2 1 ATOM 5398 C CD1 . ILE B 1 270 ? -47.509 13.139 24.628 1.00 47.93 ? 243 ILE B CD1 1 ATOM 5399 N N . SER B 1 271 ? -45.678 10.259 21.339 1.00 33.88 ? 244 SER B N 1 ATOM 5400 C CA . SER B 1 271 ? -44.524 10.882 20.732 1.00 37.92 ? 244 SER B CA 1 ATOM 5401 C C . SER B 1 271 ? -44.870 11.753 19.547 1.00 38.15 ? 244 SER B C 1 ATOM 5402 O O . SER B 1 271 ? -45.983 11.744 19.044 1.00 37.44 ? 244 SER B O 1 ATOM 5403 C CB . SER B 1 271 ? -43.479 9.837 20.325 1.00 40.22 ? 244 SER B CB 1 ATOM 5404 O OG . SER B 1 271 ? -43.588 9.476 18.970 1.00 43.89 ? 244 SER B OG 1 ATOM 5405 N N . GLN B 1 272 ? -43.861 12.491 19.111 1.00 38.66 ? 245 GLN B N 1 ATOM 5406 C CA . GLN B 1 272 ? -43.912 13.279 17.906 1.00 42.97 ? 245 GLN B CA 1 ATOM 5407 C C . GLN B 1 272 ? -44.440 12.472 16.733 1.00 43.69 ? 245 GLN B C 1 ATOM 5408 O O . GLN B 1 272 ? -45.138 13.007 15.902 1.00 43.77 ? 245 GLN B O 1 ATOM 5409 C CB . GLN B 1 272 ? -42.508 13.767 17.573 1.00 44.52 ? 245 GLN B CB 1 ATOM 5410 C CG . GLN B 1 272 ? -42.459 14.774 16.453 1.00 49.87 ? 245 GLN B CG 1 ATOM 5411 C CD . GLN B 1 272 ? -41.071 15.370 16.331 1.00 49.96 ? 245 GLN B CD 1 ATOM 5412 O OE1 . GLN B 1 272 ? -40.123 14.850 16.921 1.00 54.64 ? 245 GLN B OE1 1 ATOM 5413 N NE2 . GLN B 1 272 ? -40.937 16.456 15.586 1.00 54.66 ? 245 GLN B NE2 1 ATOM 5414 N N . TYR B 1 273 ? -44.103 11.187 16.677 1.00 44.64 ? 246 TYR B N 1 ATOM 5415 C CA . TYR B 1 273 ? -44.436 10.358 15.525 1.00 46.39 ? 246 TYR B CA 1 ATOM 5416 C C . TYR B 1 273 ? -45.584 9.385 15.774 1.00 47.74 ? 246 TYR B C 1 ATOM 5417 O O . TYR B 1 273 ? -45.805 8.511 14.955 1.00 51.44 ? 246 TYR B O 1 ATOM 5418 C CB . TYR B 1 273 ? -43.169 9.635 15.011 1.00 49.49 ? 246 TYR B CB 1 ATOM 5419 C CG . TYR B 1 273 ? -42.079 10.638 14.665 1.00 57.51 ? 246 TYR B CG 1 ATOM 5420 C CD1 . TYR B 1 273 ? -42.191 11.459 13.536 1.00 61.31 ? 246 TYR B CD1 1 ATOM 5421 C CD2 . TYR B 1 273 ? -40.978 10.816 15.492 1.00 61.60 ? 246 TYR B CD2 1 ATOM 5422 C CE1 . TYR B 1 273 ? -41.221 12.407 13.223 1.00 63.35 ? 246 TYR B CE1 1 ATOM 5423 C CE2 . TYR B 1 273 ? -40.002 11.764 15.191 1.00 65.97 ? 246 TYR B CE2 1 ATOM 5424 C CZ . TYR B 1 273 ? -40.123 12.559 14.053 1.00 69.08 ? 246 TYR B CZ 1 ATOM 5425 O OH . TYR B 1 273 ? -39.148 13.513 13.756 1.00 74.12 ? 246 TYR B OH 1 ATOM 5426 N N . SER B 1 274 ? -46.340 9.537 16.865 1.00 42.08 ? 247 SER B N 1 ATOM 5427 C CA . SER B 1 274 ? -47.546 8.727 17.041 1.00 40.86 ? 247 SER B CA 1 ATOM 5428 C C . SER B 1 274 ? -48.487 8.906 15.832 1.00 44.71 ? 247 SER B C 1 ATOM 5429 O O . SER B 1 274 ? -48.744 10.032 15.390 1.00 40.66 ? 247 SER B O 1 ATOM 5430 C CB . SER B 1 274 ? -48.319 9.149 18.277 1.00 42.26 ? 247 SER B CB 1 ATOM 5431 O OG . SER B 1 274 ? -47.568 8.981 19.457 1.00 42.77 ? 247 SER B OG 1 ATOM 5432 N N . ASP B 1 275 ? -49.014 7.815 15.308 1.00 44.90 ? 248 ASP B N 1 ATOM 5433 C CA . ASP B 1 275 ? -50.002 7.914 14.215 1.00 49.72 ? 248 ASP B CA 1 ATOM 5434 C C . ASP B 1 275 ? -51.416 8.225 14.728 1.00 48.53 ? 248 ASP B C 1 ATOM 5435 O O . ASP B 1 275 ? -51.643 8.285 15.947 1.00 49.21 ? 248 ASP B O 1 ATOM 5436 C CB . ASP B 1 275 ? -49.974 6.650 13.352 1.00 48.80 ? 248 ASP B CB 1 ATOM 5437 C CG . ASP B 1 275 ? -50.370 5.410 14.105 1.00 51.69 ? 248 ASP B CG 1 ATOM 5438 O OD1 . ASP B 1 275 ? -51.236 5.489 15.014 1.00 55.88 ? 248 ASP B OD1 1 ATOM 5439 O OD2 . ASP B 1 275 ? -49.827 4.334 13.757 1.00 56.31 ? 248 ASP B OD2 1 ATOM 5440 N N . GLU B 1 276 ? -52.355 8.408 13.802 1.00 44.37 ? 249 GLU B N 1 ATOM 5441 C CA . GLU B 1 276 ? -53.739 8.792 14.141 1.00 44.52 ? 249 GLU B CA 1 ATOM 5442 C C . GLU B 1 276 ? -54.430 7.837 15.095 1.00 41.14 ? 249 GLU B C 1 ATOM 5443 O O . GLU B 1 276 ? -55.133 8.270 16.003 1.00 43.14 ? 249 GLU B O 1 ATOM 5444 C CB . GLU B 1 276 ? -54.610 8.965 12.892 1.00 43.80 ? 249 GLU B CB 1 ATOM 5445 N N . GLU B 1 277 ? -54.218 6.548 14.911 1.00 42.27 ? 250 GLU B N 1 ATOM 5446 C CA . GLU B 1 277 ? -54.831 5.543 15.787 1.00 42.58 ? 250 GLU B CA 1 ATOM 5447 C C . GLU B 1 277 ? -54.272 5.626 17.216 1.00 41.45 ? 250 GLU B C 1 ATOM 5448 O O . GLU B 1 277 ? -55.012 5.497 18.179 1.00 44.18 ? 250 GLU B O 1 ATOM 5449 C CB . GLU B 1 277 ? -54.627 4.124 15.230 1.00 39.40 ? 250 GLU B CB 1 ATOM 5450 N N . GLU B 1 278 ? -52.969 5.830 17.338 1.00 44.70 ? 251 GLU B N 1 ATOM 5451 C CA . GLU B 1 278 ? -52.300 5.886 18.649 1.00 43.63 ? 251 GLU B CA 1 ATOM 5452 C C . GLU B 1 278 ? -52.787 7.106 19.407 1.00 42.62 ? 251 GLU B C 1 ATOM 5453 O O . GLU B 1 278 ? -53.176 7.007 20.565 1.00 42.57 ? 251 GLU B O 1 ATOM 5454 C CB . GLU B 1 278 ? -50.778 5.917 18.476 1.00 45.09 ? 251 GLU B CB 1 ATOM 5455 C CG . GLU B 1 278 ? -50.237 4.599 17.943 1.00 49.46 ? 251 GLU B CG 1 ATOM 5456 C CD . GLU B 1 278 ? -48.790 4.645 17.449 1.00 52.42 ? 251 GLU B CD 1 ATOM 5457 O OE1 . GLU B 1 278 ? -48.361 5.606 16.764 1.00 48.47 ? 251 GLU B OE1 1 ATOM 5458 O OE2 . GLU B 1 278 ? -48.080 3.669 17.740 1.00 57.47 ? 251 GLU B OE2 1 ATOM 5459 N N . ILE B 1 279 ? -52.820 8.239 18.723 1.00 42.43 ? 252 ILE B N 1 ATOM 5460 C CA . ILE B 1 279 ? -53.319 9.484 19.303 1.00 45.20 ? 252 ILE B CA 1 ATOM 5461 C C . ILE B 1 279 ? -54.788 9.342 19.713 1.00 49.29 ? 252 ILE B C 1 ATOM 5462 O O . ILE B 1 279 ? -55.189 9.776 20.802 1.00 45.69 ? 252 ILE B O 1 ATOM 5463 C CB . ILE B 1 279 ? -53.138 10.657 18.311 1.00 44.93 ? 252 ILE B CB 1 ATOM 5464 C CG1 . ILE B 1 279 ? -51.651 10.963 18.108 1.00 44.48 ? 252 ILE B CG1 1 ATOM 5465 C CG2 . ILE B 1 279 ? -53.887 11.903 18.761 1.00 43.98 ? 252 ILE B CG2 1 ATOM 5466 C CD1 . ILE B 1 279 ? -50.885 11.108 19.406 1.00 49.45 ? 252 ILE B CD1 1 ATOM 5467 N N . GLN B 1 280 ? -55.580 8.714 18.848 1.00 50.22 ? 253 GLN B N 1 ATOM 5468 C CA . GLN B 1 280 ? -57.011 8.563 19.086 1.00 50.89 ? 253 GLN B CA 1 ATOM 5469 C C . GLN B 1 280 ? -57.236 7.740 20.333 1.00 44.81 ? 253 GLN B C 1 ATOM 5470 O O . GLN B 1 280 ? -58.105 8.048 21.163 1.00 43.01 ? 253 GLN B O 1 ATOM 5471 C CB . GLN B 1 280 ? -57.671 7.876 17.880 1.00 55.71 ? 253 GLN B CB 1 ATOM 5472 C CG . GLN B 1 280 ? -59.168 7.652 18.009 1.00 64.02 ? 253 GLN B CG 1 ATOM 5473 C CD . GLN B 1 280 ? -59.785 6.952 16.794 1.00 74.54 ? 253 GLN B CD 1 ATOM 5474 O OE1 . GLN B 1 280 ? -59.079 6.482 15.885 1.00 79.87 ? 253 GLN B OE1 1 ATOM 5475 N NE2 . GLN B 1 280 ? -61.113 6.864 16.784 1.00 78.71 ? 253 GLN B NE2 1 ATOM 5476 N N . HIS B 1 281 ? -56.458 6.676 20.455 1.00 41.69 ? 254 HIS B N 1 ATOM 5477 C CA . HIS B 1 281 ? -56.553 5.823 21.616 1.00 42.87 ? 254 HIS B CA 1 ATOM 5478 C C . HIS B 1 281 ? -56.281 6.606 22.919 1.00 42.02 ? 254 HIS B C 1 ATOM 5479 O O . HIS B 1 281 ? -57.010 6.439 23.910 1.00 41.35 ? 254 HIS B O 1 ATOM 5480 C CB . HIS B 1 281 ? -55.605 4.626 21.508 1.00 45.23 ? 254 HIS B CB 1 ATOM 5481 C CG . HIS B 1 281 ? -55.655 3.752 22.716 1.00 48.72 ? 254 HIS B CG 1 ATOM 5482 N ND1 . HIS B 1 281 ? -54.664 3.730 23.676 1.00 52.49 ? 254 HIS B ND1 1 ATOM 5483 C CD2 . HIS B 1 281 ? -56.642 2.949 23.174 1.00 50.18 ? 254 HIS B CD2 1 ATOM 5484 C CE1 . HIS B 1 281 ? -55.020 2.913 24.652 1.00 51.66 ? 254 HIS B CE1 1 ATOM 5485 N NE2 . HIS B 1 281 ? -56.217 2.427 24.371 1.00 52.45 ? 254 HIS B NE2 1 ATOM 5486 N N . VAL B 1 282 ? -55.256 7.467 22.919 1.00 37.26 ? 255 VAL B N 1 ATOM 5487 C CA . VAL B 1 282 ? -54.916 8.210 24.136 1.00 36.54 ? 255 VAL B CA 1 ATOM 5488 C C . VAL B 1 282 ? -56.039 9.181 24.473 1.00 36.93 ? 255 VAL B C 1 ATOM 5489 O O . VAL B 1 282 ? -56.425 9.313 25.648 1.00 36.01 ? 255 VAL B O 1 ATOM 5490 C CB . VAL B 1 282 ? -53.555 8.942 24.030 1.00 33.38 ? 255 VAL B CB 1 ATOM 5491 C CG1 . VAL B 1 282 ? -53.278 9.779 25.274 1.00 32.50 ? 255 VAL B CG1 1 ATOM 5492 C CG2 . VAL B 1 282 ? -52.425 7.934 23.844 1.00 32.04 ? 255 VAL B CG2 1 ATOM 5493 N N . VAL B 1 283 ? -56.550 9.869 23.452 1.00 38.24 ? 256 VAL B N 1 ATOM 5494 C CA . VAL B 1 283 ? -57.634 10.835 23.646 1.00 39.36 ? 256 VAL B CA 1 ATOM 5495 C C . VAL B 1 283 ? -58.865 10.137 24.229 1.00 41.50 ? 256 VAL B C 1 ATOM 5496 O O . VAL B 1 283 ? -59.536 10.669 25.110 1.00 40.07 ? 256 VAL B O 1 ATOM 5497 C CB . VAL B 1 283 ? -57.979 11.562 22.334 1.00 42.77 ? 256 VAL B CB 1 ATOM 5498 C CG1 . VAL B 1 283 ? -59.242 12.408 22.477 1.00 41.99 ? 256 VAL B CG1 1 ATOM 5499 C CG2 . VAL B 1 283 ? -56.828 12.460 21.913 1.00 43.79 ? 256 VAL B CG2 1 ATOM 5500 N N . GLU B 1 284 ? -59.151 8.936 23.743 1.00 44.35 ? 257 GLU B N 1 ATOM 5501 C CA . GLU B 1 284 ? -60.259 8.150 24.274 1.00 43.63 ? 257 GLU B CA 1 ATOM 5502 C C . GLU B 1 284 ? -60.057 7.757 25.726 1.00 44.56 ? 257 GLU B C 1 ATOM 5503 O O . GLU B 1 284 ? -61.008 7.834 26.519 1.00 42.34 ? 257 GLU B O 1 ATOM 5504 C CB . GLU B 1 284 ? -60.502 6.909 23.425 1.00 45.92 ? 257 GLU B CB 1 ATOM 5505 C CG . GLU B 1 284 ? -61.181 7.236 22.107 1.00 53.59 ? 257 GLU B CG 1 ATOM 5506 C CD . GLU B 1 284 ? -61.482 5.998 21.276 1.00 61.31 ? 257 GLU B CD 1 ATOM 5507 O OE1 . GLU B 1 284 ? -61.597 4.894 21.869 1.00 62.38 ? 257 GLU B OE1 1 ATOM 5508 O OE2 . GLU B 1 284 ? -61.603 6.145 20.035 1.00 68.12 ? 257 GLU B OE2 1 ATOM 5509 N N . VAL B 1 285 ? -58.834 7.351 26.088 1.00 40.63 ? 258 VAL B N 1 ATOM 5510 C CA . VAL B 1 285 ? -58.526 7.068 27.494 1.00 38.75 ? 258 VAL B CA 1 ATOM 5511 C C . VAL B 1 285 ? -58.803 8.324 28.348 1.00 37.39 ? 258 VAL B C 1 ATOM 5512 O O . VAL B 1 285 ? -59.426 8.243 29.409 1.00 35.65 ? 258 VAL B O 1 ATOM 5513 C CB . VAL B 1 285 ? -57.063 6.591 27.686 1.00 42.36 ? 258 VAL B CB 1 ATOM 5514 C CG1 . VAL B 1 285 ? -56.706 6.536 29.161 1.00 42.60 ? 258 VAL B CG1 1 ATOM 5515 C CG2 . VAL B 1 285 ? -56.836 5.218 27.059 1.00 41.14 ? 258 VAL B CG2 1 ATOM 5516 N N . ILE B 1 286 ? -58.377 9.488 27.858 1.00 35.21 ? 259 ILE B N 1 ATOM 5517 C CA . ILE B 1 286 ? -58.607 10.724 28.570 1.00 38.66 ? 259 ILE B CA 1 ATOM 5518 C C . ILE B 1 286 ? -60.124 10.986 28.676 1.00 42.46 ? 259 ILE B C 1 ATOM 5519 O O . ILE B 1 286 ? -60.631 11.279 29.752 1.00 41.02 ? 259 ILE B O 1 ATOM 5520 C CB . ILE B 1 286 ? -57.863 11.917 27.921 1.00 40.63 ? 259 ILE B CB 1 ATOM 5521 C CG1 . ILE B 1 286 ? -56.337 11.742 27.995 1.00 40.35 ? 259 ILE B CG1 1 ATOM 5522 C CG2 . ILE B 1 286 ? -58.237 13.234 28.595 1.00 41.86 ? 259 ILE B CG2 1 ATOM 5523 C CD1 . ILE B 1 286 ? -55.574 12.695 27.079 1.00 42.25 ? 259 ILE B CD1 1 ATOM 5524 N N . GLN B 1 287 ? -60.838 10.871 27.563 1.00 48.07 ? 260 GLN B N 1 ATOM 5525 C CA . GLN B 1 287 ? -62.299 11.088 27.542 1.00 48.18 ? 260 GLN B CA 1 ATOM 5526 C C . GLN B 1 287 ? -63.060 10.146 28.482 1.00 47.83 ? 260 GLN B C 1 ATOM 5527 O O . GLN B 1 287 ? -64.000 10.572 29.131 1.00 52.52 ? 260 GLN B O 1 ATOM 5528 C CB . GLN B 1 287 ? -62.842 10.958 26.112 1.00 49.93 ? 260 GLN B CB 1 ATOM 5529 C CG . GLN B 1 287 ? -62.641 12.200 25.247 1.00 54.38 ? 260 GLN B CG 1 ATOM 5530 C CD . GLN B 1 287 ? -63.182 12.039 23.820 1.00 59.47 ? 260 GLN B CD 1 ATOM 5531 O OE1 . GLN B 1 287 ? -62.958 11.022 23.165 1.00 62.55 ? 260 GLN B OE1 1 ATOM 5532 N NE2 . GLN B 1 287 ? -63.863 13.063 23.325 1.00 62.32 ? 260 GLN B NE2 1 ATOM 5533 N N . ASN B 1 288 ? -62.642 8.884 28.566 1.00 46.00 ? 261 ASN B N 1 ATOM 5534 C CA . ASN B 1 288 ? -63.322 7.882 29.396 1.00 47.64 ? 261 ASN B CA 1 ATOM 5535 C C . ASN B 1 288 ? -62.907 7.857 30.867 1.00 48.45 ? 261 ASN B C 1 ATOM 5536 O O . ASN B 1 288 ? -63.428 7.051 31.646 1.00 50.37 ? 261 ASN B O 1 ATOM 5537 C CB . ASN B 1 288 ? -63.138 6.475 28.811 1.00 51.85 ? 261 ASN B CB 1 ATOM 5538 C CG . ASN B 1 288 ? -63.676 6.343 27.396 1.00 57.34 ? 261 ASN B CG 1 ATOM 5539 O OD1 . ASN B 1 288 ? -64.179 7.313 26.811 1.00 62.75 ? 261 ASN B OD1 1 ATOM 5540 N ND2 . ASN B 1 288 ? -63.563 5.136 26.832 1.00 64.94 ? 261 ASN B ND2 1 ATOM 5541 N N . SER B 1 289 ? -61.978 8.724 31.257 1.00 42.83 ? 262 SER B N 1 ATOM 5542 C CA . SER B 1 289 ? -61.524 8.774 32.630 1.00 39.83 ? 262 SER B CA 1 ATOM 5543 C C . SER B 1 289 ? -62.193 9.913 33.380 1.00 38.86 ? 262 SER B C 1 ATOM 5544 O O . SER B 1 289 ? -62.379 10.998 32.841 1.00 36.11 ? 262 SER B O 1 ATOM 5545 C CB . SER B 1 289 ? -60.001 8.982 32.665 1.00 41.09 ? 262 SER B CB 1 ATOM 5546 O OG . SER B 1 289 ? -59.552 9.224 33.990 1.00 37.42 ? 262 SER B OG 1 ATOM 5547 N N . THR B 1 290 ? -62.498 9.692 34.650 1.00 40.79 ? 263 THR B N 1 ATOM 5548 C CA . THR B 1 290 ? -62.953 10.789 35.516 1.00 46.76 ? 263 THR B CA 1 ATOM 5549 C C . THR B 1 290 ? -61.813 11.697 36.023 1.00 48.81 ? 263 THR B C 1 ATOM 5550 O O . THR B 1 290 ? -62.083 12.743 36.621 1.00 51.87 ? 263 THR B O 1 ATOM 5551 C CB . THR B 1 290 ? -63.736 10.243 36.727 1.00 47.99 ? 263 THR B CB 1 ATOM 5552 O OG1 . THR B 1 290 ? -62.900 9.362 37.477 1.00 47.13 ? 263 THR B OG1 1 ATOM 5553 C CG2 . THR B 1 290 ? -64.977 9.483 36.253 1.00 49.34 ? 263 THR B CG2 1 ATOM 5554 N N . ALA B 1 291 ? -60.553 11.319 35.774 1.00 47.53 ? 264 ALA B N 1 ATOM 5555 C CA . ALA B 1 291 ? -59.412 12.140 36.197 1.00 42.90 ? 264 ALA B CA 1 ATOM 5556 C C . ALA B 1 291 ? -59.476 13.534 35.588 1.00 38.62 ? 264 ALA B C 1 ATOM 5557 O O . ALA B 1 291 ? -59.749 13.713 34.404 1.00 39.56 ? 264 ALA B O 1 ATOM 5558 C CB . ALA B 1 291 ? -58.098 11.473 35.824 1.00 43.43 ? 264 ALA B CB 1 ATOM 5559 N N . LYS B 1 292 ? -59.205 14.519 36.421 1.00 37.10 ? 265 LYS B N 1 ATOM 5560 C CA . LYS B 1 292 ? -59.184 15.907 36.019 1.00 36.65 ? 265 LYS B CA 1 ATOM 5561 C C . LYS B 1 292 ? -57.733 16.389 35.927 1.00 33.07 ? 265 LYS B C 1 ATOM 5562 O O . LYS B 1 292 ? -57.393 17.219 35.078 1.00 34.60 ? 265 LYS B O 1 ATOM 5563 C CB . LYS B 1 292 ? -59.959 16.729 37.065 1.00 40.78 ? 265 LYS B CB 1 ATOM 5564 C CG . LYS B 1 292 ? -60.414 18.116 36.623 1.00 46.22 ? 265 LYS B CG 1 ATOM 5565 C CD . LYS B 1 292 ? -60.900 18.939 37.823 1.00 52.90 ? 265 LYS B CD 1 ATOM 5566 C CE . LYS B 1 292 ? -62.031 19.925 37.507 1.00 56.02 ? 265 LYS B CE 1 ATOM 5567 N NZ . LYS B 1 292 ? -61.658 21.010 36.557 1.00 56.18 ? 265 LYS B NZ 1 ATOM 5568 N N . VAL B 1 293 ? -56.905 15.931 36.852 1.00 33.13 ? 266 VAL B N 1 ATOM 5569 C CA . VAL B 1 293 ? -55.489 16.284 36.887 1.00 31.86 ? 266 VAL B CA 1 ATOM 5570 C C . VAL B 1 293 ? -54.734 15.309 36.003 1.00 30.80 ? 266 VAL B C 1 ATOM 5571 O O . VAL B 1 293 ? -54.797 14.105 36.219 1.00 30.64 ? 266 VAL B O 1 ATOM 5572 C CB . VAL B 1 293 ? -54.922 16.213 38.307 1.00 32.55 ? 266 VAL B CB 1 ATOM 5573 C CG1 . VAL B 1 293 ? -53.443 16.623 38.341 1.00 32.01 ? 266 VAL B CG1 1 ATOM 5574 C CG2 . VAL B 1 293 ? -55.740 17.095 39.246 1.00 33.69 ? 266 VAL B CG2 1 ATOM 5575 N N . ILE B 1 294 ? -54.026 15.832 35.012 1.00 31.09 ? 267 ILE B N 1 ATOM 5576 C CA . ILE B 1 294 ? -53.174 15.004 34.169 1.00 30.68 ? 267 ILE B CA 1 ATOM 5577 C C . ILE B 1 294 ? -51.710 15.479 34.220 1.00 28.45 ? 267 ILE B C 1 ATOM 5578 O O . ILE B 1 294 ? -51.395 16.625 33.870 1.00 26.11 ? 267 ILE B O 1 ATOM 5579 C CB . ILE B 1 294 ? -53.707 14.956 32.726 1.00 31.89 ? 267 ILE B CB 1 ATOM 5580 C CG1 . ILE B 1 294 ? -55.179 14.534 32.769 1.00 33.21 ? 267 ILE B CG1 1 ATOM 5581 C CG2 . ILE B 1 294 ? -52.875 13.984 31.892 1.00 33.72 ? 267 ILE B CG2 1 ATOM 5582 C CD1 . ILE B 1 294 ? -55.888 14.527 31.435 1.00 35.11 ? 267 ILE B CD1 1 ATOM 5583 N N . VAL B 1 295 ? -50.836 14.571 34.656 1.00 29.38 ? 268 VAL B N 1 ATOM 5584 C CA . VAL B 1 295 ? -49.397 14.806 34.748 1.00 29.28 ? 268 VAL B CA 1 ATOM 5585 C C . VAL B 1 295 ? -48.737 14.384 33.446 1.00 29.16 ? 268 VAL B C 1 ATOM 5586 O O . VAL B 1 295 ? -48.886 13.251 33.014 1.00 29.67 ? 268 VAL B O 1 ATOM 5587 C CB . VAL B 1 295 ? -48.771 13.997 35.884 1.00 30.19 ? 268 VAL B CB 1 ATOM 5588 C CG1 . VAL B 1 295 ? -47.278 14.305 36.013 1.00 30.06 ? 268 VAL B CG1 1 ATOM 5589 C CG2 . VAL B 1 295 ? -49.473 14.329 37.177 1.00 31.93 ? 268 VAL B CG2 1 ATOM 5590 N N . VAL B 1 296 ? -48.011 15.298 32.829 1.00 27.55 ? 269 VAL B N 1 ATOM 5591 C CA . VAL B 1 296 ? -47.457 15.064 31.493 1.00 27.32 ? 269 VAL B CA 1 ATOM 5592 C C . VAL B 1 296 ? -45.950 15.318 31.492 1.00 27.04 ? 269 VAL B C 1 ATOM 5593 O O . VAL B 1 296 ? -45.513 16.452 31.687 1.00 26.76 ? 269 VAL B O 1 ATOM 5594 C CB . VAL B 1 296 ? -48.151 15.958 30.448 1.00 28.86 ? 269 VAL B CB 1 ATOM 5595 C CG1 . VAL B 1 296 ? -47.659 15.644 29.040 1.00 29.67 ? 269 VAL B CG1 1 ATOM 5596 C CG2 . VAL B 1 296 ? -49.671 15.800 30.515 1.00 31.10 ? 269 VAL B CG2 1 ATOM 5597 N N . PHE B 1 297 ? -45.169 14.259 31.286 1.00 25.75 ? 270 PHE B N 1 ATOM 5598 C CA . PHE B 1 297 ? -43.710 14.350 31.233 1.00 25.98 ? 270 PHE B CA 1 ATOM 5599 C C . PHE B 1 297 ? -43.282 14.211 29.777 1.00 25.84 ? 270 PHE B C 1 ATOM 5600 O O . PHE B 1 297 ? -43.226 13.114 29.259 1.00 24.91 ? 270 PHE B O 1 ATOM 5601 C CB . PHE B 1 297 ? -43.069 13.276 32.097 1.00 25.49 ? 270 PHE B CB 1 ATOM 5602 C CG . PHE B 1 297 ? -42.010 13.787 33.025 1.00 26.08 ? 270 PHE B CG 1 ATOM 5603 C CD1 . PHE B 1 297 ? -40.780 14.196 32.544 1.00 26.89 ? 270 PHE B CD1 1 ATOM 5604 C CD2 . PHE B 1 297 ? -42.239 13.859 34.381 1.00 27.63 ? 270 PHE B CD2 1 ATOM 5605 C CE1 . PHE B 1 297 ? -39.792 14.690 33.413 1.00 27.91 ? 270 PHE B CE1 1 ATOM 5606 C CE2 . PHE B 1 297 ? -41.260 14.333 35.250 1.00 28.84 ? 270 PHE B CE2 1 ATOM 5607 C CZ . PHE B 1 297 ? -40.031 14.744 34.764 1.00 27.62 ? 270 PHE B CZ 1 ATOM 5608 N N . SER B 1 298 ? -43.010 15.329 29.113 1.00 24.92 ? 271 SER B N 1 ATOM 5609 C CA . SER B 1 298 ? -42.785 15.337 27.665 1.00 25.44 ? 271 SER B CA 1 ATOM 5610 C C . SER B 1 298 ? -42.169 16.633 27.203 1.00 25.90 ? 271 SER B C 1 ATOM 5611 O O . SER B 1 298 ? -42.342 17.683 27.831 1.00 25.21 ? 271 SER B O 1 ATOM 5612 C CB . SER B 1 298 ? -44.131 15.166 26.906 1.00 27.38 ? 271 SER B CB 1 ATOM 5613 O OG . SER B 1 298 ? -43.975 15.176 25.470 1.00 26.82 ? 271 SER B OG 1 ATOM 5614 N N . SER B 1 299 ? -41.453 16.565 26.088 1.00 26.16 ? 272 SER B N 1 ATOM 5615 C CA . SER B 1 299 ? -41.084 17.753 25.348 1.00 26.41 ? 272 SER B CA 1 ATOM 5616 C C . SER B 1 299 ? -42.311 18.275 24.594 1.00 27.66 ? 272 SER B C 1 ATOM 5617 O O . SER B 1 299 ? -43.315 17.559 24.413 1.00 26.71 ? 272 SER B O 1 ATOM 5618 C CB . SER B 1 299 ? -39.976 17.436 24.338 1.00 26.90 ? 272 SER B CB 1 ATOM 5619 O OG . SER B 1 299 ? -40.484 16.586 23.311 1.00 28.67 ? 272 SER B OG 1 ATOM 5620 N N . GLY B 1 300 ? -42.199 19.514 24.124 1.00 27.37 ? 273 GLY B N 1 ATOM 5621 C CA . GLY B 1 300 ? -43.219 20.128 23.287 1.00 29.28 ? 273 GLY B CA 1 ATOM 5622 C C . GLY B 1 300 ? -43.477 19.369 22.014 1.00 28.73 ? 273 GLY B C 1 ATOM 5623 O O . GLY B 1 300 ? -44.625 19.056 21.710 1.00 32.03 ? 273 GLY B O 1 ATOM 5624 N N . PRO B 1 301 ? -42.418 19.036 21.269 1.00 30.37 ? 274 PRO B N 1 ATOM 5625 C CA . PRO B 1 301 ? -42.638 18.329 20.011 1.00 30.53 ? 274 PRO B CA 1 ATOM 5626 C C . PRO B 1 301 ? -43.328 16.990 20.173 1.00 29.76 ? 274 PRO B C 1 ATOM 5627 O O . PRO B 1 301 ? -44.162 16.606 19.340 1.00 30.45 ? 274 PRO B O 1 ATOM 5628 C CB . PRO B 1 301 ? -41.215 18.174 19.443 1.00 31.09 ? 274 PRO B CB 1 ATOM 5629 C CG . PRO B 1 301 ? -40.467 19.317 20.027 1.00 30.47 ? 274 PRO B CG 1 ATOM 5630 C CD . PRO B 1 301 ? -41.024 19.488 21.410 1.00 30.82 ? 274 PRO B CD 1 ATOM 5631 N N . ASP B 1 302 ? -43.009 16.269 21.241 1.00 31.40 ? 275 ASP B N 1 ATOM 5632 C CA . ASP B 1 302 ? -43.664 14.978 21.483 1.00 32.64 ? 275 ASP B CA 1 ATOM 5633 C C . ASP B 1 302 ? -45.097 15.090 21.993 1.00 31.58 ? 275 ASP B C 1 ATOM 5634 O O . ASP B 1 302 ? -45.852 14.137 21.881 1.00 28.54 ? 275 ASP B O 1 ATOM 5635 C CB . ASP B 1 302 ? -42.854 14.123 22.450 1.00 35.01 ? 275 ASP B CB 1 ATOM 5636 C CG . ASP B 1 302 ? -41.587 13.588 21.820 1.00 36.99 ? 275 ASP B CG 1 ATOM 5637 O OD1 . ASP B 1 302 ? -41.692 12.945 20.753 1.00 36.11 ? 275 ASP B OD1 1 ATOM 5638 O OD2 . ASP B 1 302 ? -40.492 13.827 22.391 1.00 38.25 ? 275 ASP B OD2 1 ATOM 5639 N N . LEU B 1 303 ? -45.456 16.234 22.570 1.00 29.94 ? 276 LEU B N 1 ATOM 5640 C CA . LEU B 1 303 ? -46.802 16.438 23.091 1.00 30.12 ? 276 LEU B CA 1 ATOM 5641 C C . LEU B 1 303 ? -47.762 17.023 22.039 1.00 33.53 ? 276 LEU B C 1 ATOM 5642 O O . LEU B 1 303 ? -48.973 16.818 22.113 1.00 32.36 ? 276 LEU B O 1 ATOM 5643 C CB . LEU B 1 303 ? -46.759 17.384 24.281 1.00 29.23 ? 276 LEU B CB 1 ATOM 5644 C CG . LEU B 1 303 ? -48.087 17.569 25.004 1.00 28.94 ? 276 LEU B CG 1 ATOM 5645 C CD1 . LEU B 1 303 ? -48.693 16.257 25.488 1.00 29.85 ? 276 LEU B CD1 1 ATOM 5646 C CD2 . LEU B 1 303 ? -47.935 18.548 26.147 1.00 31.67 ? 276 LEU B CD2 1 ATOM 5647 N N . GLU B 1 304 ? -47.203 17.760 21.085 1.00 34.07 ? 277 GLU B N 1 ATOM 5648 C CA . GLU B 1 304 ? -47.979 18.583 20.156 1.00 38.81 ? 277 GLU B CA 1 ATOM 5649 C C . GLU B 1 304 ? -49.102 17.852 19.408 1.00 37.40 ? 277 GLU B C 1 ATOM 5650 O O . GLU B 1 304 ? -50.225 18.340 19.362 1.00 37.73 ? 277 GLU B O 1 ATOM 5651 C CB . GLU B 1 304 ? -47.040 19.291 19.162 1.00 38.98 ? 277 GLU B CB 1 ATOM 5652 C CG . GLU B 1 304 ? -47.750 20.267 18.248 1.00 40.54 ? 277 GLU B CG 1 ATOM 5653 C CD . GLU B 1 304 ? -46.818 20.931 17.255 1.00 41.33 ? 277 GLU B CD 1 ATOM 5654 O OE1 . GLU B 1 304 ? -45.729 20.381 16.974 1.00 46.39 ? 277 GLU B OE1 1 ATOM 5655 O OE2 . GLU B 1 304 ? -47.182 21.999 16.732 1.00 42.35 ? 277 GLU B OE2 1 ATOM 5656 N N . PRO B 1 305 ? -48.811 16.677 18.837 1.00 38.36 ? 278 PRO B N 1 ATOM 5657 C CA . PRO B 1 305 ? -49.899 15.981 18.141 1.00 38.82 ? 278 PRO B CA 1 ATOM 5658 C C . PRO B 1 305 ? -51.062 15.574 19.058 1.00 38.94 ? 278 PRO B C 1 ATOM 5659 O O . PRO B 1 305 ? -52.225 15.621 18.645 1.00 37.92 ? 278 PRO B O 1 ATOM 5660 C CB . PRO B 1 305 ? -49.209 14.755 17.536 1.00 38.15 ? 278 PRO B CB 1 ATOM 5661 C CG . PRO B 1 305 ? -47.762 15.114 17.499 1.00 39.25 ? 278 PRO B CG 1 ATOM 5662 C CD . PRO B 1 305 ? -47.537 15.961 18.714 1.00 37.71 ? 278 PRO B CD 1 ATOM 5663 N N . LEU B 1 306 ? -50.769 15.204 20.297 1.00 35.66 ? 279 LEU B N 1 ATOM 5664 C CA . LEU B 1 306 ? -51.835 14.861 21.220 1.00 36.05 ? 279 LEU B CA 1 ATOM 5665 C C . LEU B 1 306 ? -52.680 16.088 21.524 1.00 37.02 ? 279 LEU B C 1 ATOM 5666 O O . LEU B 1 306 ? -53.913 16.021 21.498 1.00 40.09 ? 279 LEU B O 1 ATOM 5667 C CB . LEU B 1 306 ? -51.295 14.272 22.526 1.00 36.00 ? 279 LEU B CB 1 ATOM 5668 C CG . LEU B 1 306 ? -52.364 14.084 23.600 1.00 36.35 ? 279 LEU B CG 1 ATOM 5669 C CD1 . LEU B 1 306 ? -53.436 13.130 23.118 1.00 37.18 ? 279 LEU B CD1 1 ATOM 5670 C CD2 . LEU B 1 306 ? -51.766 13.576 24.908 1.00 37.70 ? 279 LEU B CD2 1 ATOM 5671 N N . ILE B 1 307 ? -52.021 17.203 21.799 1.00 33.87 ? 280 ILE B N 1 ATOM 5672 C CA . ILE B 1 307 ? -52.724 18.410 22.182 1.00 37.14 ? 280 ILE B CA 1 ATOM 5673 C C . ILE B 1 307 ? -53.595 18.921 21.037 1.00 39.36 ? 280 ILE B C 1 ATOM 5674 O O . ILE B 1 307 ? -54.720 19.335 21.277 1.00 37.68 ? 280 ILE B O 1 ATOM 5675 C CB . ILE B 1 307 ? -51.756 19.487 22.687 1.00 37.80 ? 280 ILE B CB 1 ATOM 5676 C CG1 . ILE B 1 307 ? -51.290 19.147 24.105 1.00 38.21 ? 280 ILE B CG1 1 ATOM 5677 C CG2 . ILE B 1 307 ? -52.378 20.869 22.660 1.00 39.94 ? 280 ILE B CG2 1 ATOM 5678 C CD1 . ILE B 1 307 ? -52.342 19.234 25.205 1.00 39.41 ? 280 ILE B CD1 1 ATOM 5679 N N . LYS B 1 308 ? -53.103 18.843 19.801 1.00 39.78 ? 281 LYS B N 1 ATOM 5680 C CA . LYS B 1 308 ? -53.901 19.255 18.647 1.00 41.48 ? 281 LYS B CA 1 ATOM 5681 C C . LYS B 1 308 ? -55.215 18.494 18.586 1.00 40.73 ? 281 LYS B C 1 ATOM 5682 O O . LYS B 1 308 ? -56.252 19.086 18.376 1.00 40.11 ? 281 LYS B O 1 ATOM 5683 C CB . LYS B 1 308 ? -53.149 19.060 17.342 1.00 40.41 ? 281 LYS B CB 1 ATOM 5684 C CG . LYS B 1 308 ? -52.108 20.122 17.134 1.00 43.16 ? 281 LYS B CG 1 ATOM 5685 C CD . LYS B 1 308 ? -51.405 19.946 15.808 1.00 46.96 ? 281 LYS B CD 1 ATOM 5686 C CE . LYS B 1 308 ? -50.451 21.100 15.586 1.00 50.91 ? 281 LYS B CE 1 ATOM 5687 N NZ . LYS B 1 308 ? -49.572 20.837 14.421 1.00 55.85 ? 281 LYS B NZ 1 ATOM 5688 N N . GLU B 1 309 ? -55.174 17.192 18.811 1.00 42.48 ? 282 GLU B N 1 ATOM 5689 C CA . GLU B 1 309 ? -56.392 16.391 18.779 1.00 45.69 ? 282 GLU B CA 1 ATOM 5690 C C . GLU B 1 309 ? -57.307 16.702 19.969 1.00 46.01 ? 282 GLU B C 1 ATOM 5691 O O . GLU B 1 309 ? -58.524 16.732 19.817 1.00 49.01 ? 282 GLU B O 1 ATOM 5692 C CB . GLU B 1 309 ? -56.067 14.900 18.717 1.00 43.41 ? 282 GLU B CB 1 ATOM 5693 C CG . GLU B 1 309 ? -57.285 13.986 18.608 1.00 48.97 ? 282 GLU B CG 1 ATOM 5694 C CD . GLU B 1 309 ? -58.087 14.158 17.313 1.00 51.24 ? 282 GLU B CD 1 ATOM 5695 O OE1 . GLU B 1 309 ? -59.226 13.649 17.261 1.00 53.00 ? 282 GLU B OE1 1 ATOM 5696 O OE2 . GLU B 1 309 ? -57.587 14.775 16.352 1.00 46.49 ? 282 GLU B OE2 1 ATOM 5697 N N . ILE B 1 310 ? -56.728 16.938 21.140 1.00 43.95 ? 283 ILE B N 1 ATOM 5698 C CA . ILE B 1 310 ? -57.517 17.286 22.312 1.00 41.98 ? 283 ILE B CA 1 ATOM 5699 C C . ILE B 1 310 ? -58.267 18.607 22.083 1.00 41.47 ? 283 ILE B C 1 ATOM 5700 O O . ILE B 1 310 ? -59.425 18.755 22.470 1.00 39.09 ? 283 ILE B O 1 ATOM 5701 C CB . ILE B 1 310 ? -56.638 17.364 23.567 1.00 42.40 ? 283 ILE B CB 1 ATOM 5702 C CG1 . ILE B 1 310 ? -56.220 15.948 23.977 1.00 44.84 ? 283 ILE B CG1 1 ATOM 5703 C CG2 . ILE B 1 310 ? -57.390 17.986 24.723 1.00 44.55 ? 283 ILE B CG2 1 ATOM 5704 C CD1 . ILE B 1 310 ? -55.179 15.900 25.076 1.00 47.67 ? 283 ILE B CD1 1 ATOM 5705 N N . VAL B 1 311 ? -57.581 19.560 21.473 1.00 39.11 ? 284 VAL B N 1 ATOM 5706 C CA . VAL B 1 311 ? -58.168 20.824 21.101 1.00 41.29 ? 284 VAL B CA 1 ATOM 5707 C C . VAL B 1 311 ? -59.263 20.604 20.037 1.00 44.80 ? 284 VAL B C 1 ATOM 5708 O O . VAL B 1 311 ? -60.367 21.117 20.162 1.00 45.53 ? 284 VAL B O 1 ATOM 5709 C CB . VAL B 1 311 ? -57.078 21.778 20.606 1.00 41.73 ? 284 VAL B CB 1 ATOM 5710 C CG1 . VAL B 1 311 ? -57.665 22.989 19.913 1.00 41.99 ? 284 VAL B CG1 1 ATOM 5711 C CG2 . VAL B 1 311 ? -56.217 22.220 21.781 1.00 43.85 ? 284 VAL B CG2 1 ATOM 5712 N N . ARG B 1 312 ? -58.969 19.797 19.030 1.00 44.48 ? 285 ARG B N 1 ATOM 5713 C CA . ARG B 1 312 ? -59.954 19.471 18.008 1.00 49.12 ? 285 ARG B CA 1 ATOM 5714 C C . ARG B 1 312 ? -61.264 18.966 18.633 1.00 49.57 ? 285 ARG B C 1 ATOM 5715 O O . ARG B 1 312 ? -62.333 19.356 18.209 1.00 57.39 ? 285 ARG B O 1 ATOM 5716 C CB . ARG B 1 312 ? -59.396 18.439 17.028 1.00 52.38 ? 285 ARG B CB 1 ATOM 5717 C CG . ARG B 1 312 ? -59.607 18.815 15.568 1.00 59.05 ? 285 ARG B CG 1 ATOM 5718 C CD . ARG B 1 312 ? -59.539 17.603 14.656 1.00 61.07 ? 285 ARG B CD 1 ATOM 5719 N NE . ARG B 1 312 ? -60.675 16.742 14.994 1.00 64.34 ? 285 ARG B NE 1 ATOM 5720 C CZ . ARG B 1 312 ? -60.710 15.415 14.939 1.00 64.79 ? 285 ARG B CZ 1 ATOM 5721 N NH1 . ARG B 1 312 ? -61.824 14.793 15.307 1.00 64.93 ? 285 ARG B NH1 1 ATOM 5722 N NH2 . ARG B 1 312 ? -59.658 14.711 14.542 1.00 72.70 ? 285 ARG B NH2 1 ATOM 5723 N N . ARG B 1 313 ? -61.178 18.119 19.653 1.00 48.08 ? 286 ARG B N 1 ATOM 5724 C CA . ARG B 1 313 ? -62.357 17.572 20.303 1.00 42.90 ? 286 ARG B CA 1 ATOM 5725 C C . ARG B 1 313 ? -62.866 18.413 21.457 1.00 44.64 ? 286 ARG B C 1 ATOM 5726 O O . ARG B 1 313 ? -63.776 18.006 22.153 1.00 46.77 ? 286 ARG B O 1 ATOM 5727 C CB . ARG B 1 313 ? -62.062 16.170 20.809 1.00 46.66 ? 286 ARG B CB 1 ATOM 5728 C CG . ARG B 1 313 ? -61.555 15.250 19.728 1.00 49.33 ? 286 ARG B CG 1 ATOM 5729 C CD . ARG B 1 313 ? -61.825 13.818 20.110 1.00 55.39 ? 286 ARG B CD 1 ATOM 5730 N NE . ARG B 1 313 ? -61.284 12.858 19.149 1.00 59.79 ? 286 ARG B NE 1 ATOM 5731 C CZ . ARG B 1 313 ? -61.518 11.548 19.199 1.00 64.81 ? 286 ARG B CZ 1 ATOM 5732 N NH1 . ARG B 1 313 ? -62.284 11.029 20.162 1.00 66.18 ? 286 ARG B NH1 1 ATOM 5733 N NH2 . ARG B 1 313 ? -60.976 10.742 18.297 1.00 67.69 ? 286 ARG B NH2 1 ATOM 5734 N N . ASN B 1 314 ? -62.251 19.560 21.706 1.00 47.51 ? 287 ASN B N 1 ATOM 5735 C CA . ASN B 1 314 ? -62.737 20.483 22.718 1.00 52.05 ? 287 ASN B CA 1 ATOM 5736 C C . ASN B 1 314 ? -62.801 19.889 24.137 1.00 49.87 ? 287 ASN B C 1 ATOM 5737 O O . ASN B 1 314 ? -63.755 20.123 24.873 1.00 46.32 ? 287 ASN B O 1 ATOM 5738 C CB . ASN B 1 314 ? -64.120 21.013 22.302 1.00 60.86 ? 287 ASN B CB 1 ATOM 5739 C CG . ASN B 1 314 ? -64.451 22.348 22.948 1.00 71.05 ? 287 ASN B CG 1 ATOM 5740 O OD1 . ASN B 1 314 ? -63.552 23.081 23.344 1.00 70.83 ? 287 ASN B OD1 1 ATOM 5741 N ND2 . ASN B 1 314 ? -65.738 22.673 23.062 1.00 79.47 ? 287 ASN B ND2 1 ATOM 5742 N N . ILE B 1 315 ? -61.774 19.141 24.536 1.00 50.05 ? 288 ILE B N 1 ATOM 5743 C CA . ILE B 1 315 ? -61.740 18.561 25.875 1.00 46.90 ? 288 ILE B CA 1 ATOM 5744 C C . ILE B 1 315 ? -61.253 19.606 26.859 1.00 48.15 ? 288 ILE B C 1 ATOM 5745 O O . ILE B 1 315 ? -60.079 19.960 26.914 1.00 47.78 ? 288 ILE B O 1 ATOM 5746 C CB . ILE B 1 315 ? -60.901 17.291 25.921 1.00 47.45 ? 288 ILE B CB 1 ATOM 5747 C CG1 . ILE B 1 315 ? -61.590 16.224 25.068 1.00 49.38 ? 288 ILE B CG1 1 ATOM 5748 C CG2 . ILE B 1 315 ? -60.728 16.792 27.356 1.00 48.83 ? 288 ILE B CG2 1 ATOM 5749 C CD1 . ILE B 1 315 ? -60.670 15.127 24.589 1.00 49.72 ? 288 ILE B CD1 1 ATOM 5750 N N . THR B 1 316 ? -62.187 20.060 27.675 1.00 46.20 ? 289 THR B N 1 ATOM 5751 C CA . THR B 1 316 ? -62.052 21.270 28.434 1.00 45.00 ? 289 THR B CA 1 ATOM 5752 C C . THR B 1 316 ? -61.991 20.899 29.910 1.00 41.59 ? 289 THR B C 1 ATOM 5753 O O . THR B 1 316 ? -62.354 19.792 30.281 1.00 41.48 ? 289 THR B O 1 ATOM 5754 C CB . THR B 1 316 ? -63.292 22.137 28.054 1.00 49.12 ? 289 THR B CB 1 ATOM 5755 O OG1 . THR B 1 316 ? -62.865 23.377 27.493 1.00 54.92 ? 289 THR B OG1 1 ATOM 5756 C CG2 . THR B 1 316 ? -64.251 22.349 29.208 1.00 47.13 ? 289 THR B CG2 1 ATOM 5757 N N . GLY B 1 317 ? -61.487 21.799 30.751 1.00 42.37 ? 290 GLY B N 1 ATOM 5758 C CA . GLY B 1 317 ? -61.538 21.597 32.201 1.00 44.24 ? 290 GLY B CA 1 ATOM 5759 C C . GLY B 1 317 ? -60.511 20.663 32.832 1.00 45.77 ? 290 GLY B C 1 ATOM 5760 O O . GLY B 1 317 ? -60.619 20.353 34.023 1.00 46.93 ? 290 GLY B O 1 ATOM 5761 N N . LYS B 1 318 ? -59.508 20.214 32.072 1.00 42.24 ? 291 LYS B N 1 ATOM 5762 C CA . LYS B 1 318 ? -58.418 19.430 32.673 1.00 38.42 ? 291 LYS B CA 1 ATOM 5763 C C . LYS B 1 318 ? -57.414 20.325 33.378 1.00 35.96 ? 291 LYS B C 1 ATOM 5764 O O . LYS B 1 318 ? -57.145 21.447 32.945 1.00 33.34 ? 291 LYS B O 1 ATOM 5765 C CB . LYS B 1 318 ? -57.710 18.589 31.618 1.00 41.11 ? 291 LYS B CB 1 ATOM 5766 C CG . LYS B 1 318 ? -58.620 17.587 30.934 1.00 42.62 ? 291 LYS B CG 1 ATOM 5767 C CD . LYS B 1 318 ? -59.286 16.640 31.921 1.00 42.15 ? 291 LYS B CD 1 ATOM 5768 C CE . LYS B 1 318 ? -60.306 15.772 31.214 1.00 44.55 ? 291 LYS B CE 1 ATOM 5769 N NZ . LYS B 1 318 ? -61.072 14.963 32.190 1.00 48.02 ? 291 LYS B NZ 1 ATOM 5770 N N . ILE B 1 319 ? -56.876 19.833 34.487 1.00 35.13 ? 292 ILE B N 1 ATOM 5771 C CA . ILE B 1 319 ? -55.755 20.487 35.159 1.00 35.24 ? 292 ILE B CA 1 ATOM 5772 C C . ILE B 1 319 ? -54.472 19.790 34.703 1.00 33.07 ? 292 ILE B C 1 ATOM 5773 O O . ILE B 1 319 ? -54.191 18.653 35.110 1.00 34.29 ? 292 ILE B O 1 ATOM 5774 C CB . ILE B 1 319 ? -55.893 20.405 36.694 1.00 36.27 ? 292 ILE B CB 1 ATOM 5775 C CG1 . ILE B 1 319 ? -57.140 21.193 37.136 1.00 37.89 ? 292 ILE B CG1 1 ATOM 5776 C CG2 . ILE B 1 319 ? -54.655 20.974 37.388 1.00 36.73 ? 292 ILE B CG2 1 ATOM 5777 C CD1 . ILE B 1 319 ? -57.499 21.030 38.599 1.00 36.04 ? 292 ILE B CD1 1 ATOM 5778 N N . TRP B 1 320 ? -53.705 20.471 33.858 1.00 30.30 ? 293 TRP B N 1 ATOM 5779 C CA . TRP B 1 320 ? -52.446 19.931 33.335 1.00 30.02 ? 293 TRP B CA 1 ATOM 5780 C C . TRP B 1 320 ? -51.285 20.277 34.256 1.00 29.92 ? 293 TRP B C 1 ATOM 5781 O O . TRP B 1 320 ? -51.086 21.435 34.600 1.00 29.55 ? 293 TRP B O 1 ATOM 5782 C CB . TRP B 1 320 ? -52.159 20.474 31.940 1.00 29.66 ? 293 TRP B CB 1 ATOM 5783 C CG . TRP B 1 320 ? -53.251 20.223 30.971 1.00 32.63 ? 293 TRP B CG 1 ATOM 5784 C CD1 . TRP B 1 320 ? -54.234 21.112 30.584 1.00 35.62 ? 293 TRP B CD1 1 ATOM 5785 C CD2 . TRP B 1 320 ? -53.501 19.015 30.257 1.00 33.25 ? 293 TRP B CD2 1 ATOM 5786 N NE1 . TRP B 1 320 ? -55.067 20.516 29.676 1.00 35.99 ? 293 TRP B NE1 1 ATOM 5787 C CE2 . TRP B 1 320 ? -54.637 19.232 29.453 1.00 32.28 ? 293 TRP B CE2 1 ATOM 5788 C CE3 . TRP B 1 320 ? -52.856 17.782 30.190 1.00 33.31 ? 293 TRP B CE3 1 ATOM 5789 C CZ2 . TRP B 1 320 ? -55.156 18.253 28.628 1.00 33.25 ? 293 TRP B CZ2 1 ATOM 5790 C CZ3 . TRP B 1 320 ? -53.376 16.807 29.357 1.00 37.22 ? 293 TRP B CZ3 1 ATOM 5791 C CH2 . TRP B 1 320 ? -54.519 17.050 28.587 1.00 34.05 ? 293 TRP B CH2 1 ATOM 5792 N N . LEU B 1 321 ? -50.525 19.264 34.660 1.00 30.11 ? 294 LEU B N 1 ATOM 5793 C CA . LEU B 1 321 ? -49.273 19.471 35.379 1.00 31.67 ? 294 LEU B CA 1 ATOM 5794 C C . LEU B 1 321 ? -48.111 19.167 34.429 1.00 29.46 ? 294 LEU B C 1 ATOM 5795 O O . LEU B 1 321 ? -47.956 18.026 33.932 1.00 28.54 ? 294 LEU B O 1 ATOM 5796 C CB . LEU B 1 321 ? -49.283 18.579 36.614 1.00 35.76 ? 294 LEU B CB 1 ATOM 5797 C CG . LEU B 1 321 ? -48.172 18.712 37.655 1.00 41.79 ? 294 LEU B CG 1 ATOM 5798 C CD1 . LEU B 1 321 ? -47.846 20.167 37.993 1.00 42.03 ? 294 LEU B CD1 1 ATOM 5799 C CD2 . LEU B 1 321 ? -48.559 17.956 38.920 1.00 45.09 ? 294 LEU B CD2 1 ATOM 5800 N N . ALA B 1 322 ? -47.303 20.196 34.152 1.00 26.86 ? 295 ALA B N 1 ATOM 5801 C CA . ALA B 1 322 ? -46.351 20.153 33.035 1.00 28.00 ? 295 ALA B CA 1 ATOM 5802 C C . ALA B 1 322 ? -44.919 19.951 33.514 1.00 28.36 ? 295 ALA B C 1 ATOM 5803 O O . ALA B 1 322 ? -44.442 20.692 34.360 1.00 25.28 ? 295 ALA B O 1 ATOM 5804 C CB . ALA B 1 322 ? -46.438 21.432 32.220 1.00 27.46 ? 295 ALA B CB 1 ATOM 5805 N N . SER B 1 323 ? -44.222 18.982 32.931 1.00 26.36 ? 296 SER B N 1 ATOM 5806 C CA . SER B 1 323 ? -42.797 18.916 33.119 1.00 27.98 ? 296 SER B CA 1 ATOM 5807 C C . SER B 1 323 ? -42.129 20.118 32.418 1.00 29.41 ? 296 SER B C 1 ATOM 5808 O O . SER B 1 323 ? -42.676 20.760 31.519 1.00 29.12 ? 296 SER B O 1 ATOM 5809 C CB . SER B 1 323 ? -42.187 17.568 32.622 1.00 27.27 ? 296 SER B CB 1 ATOM 5810 O OG . SER B 1 323 ? -42.156 17.504 31.213 1.00 27.47 ? 296 SER B OG 1 ATOM 5811 N N . GLU B 1 324 ? -40.887 20.335 32.783 1.00 29.00 ? 297 GLU B N 1 ATOM 5812 C CA . GLU B 1 324 ? -40.194 21.548 32.489 1.00 32.63 ? 297 GLU B CA 1 ATOM 5813 C C . GLU B 1 324 ? -39.938 21.728 30.991 1.00 29.94 ? 297 GLU B C 1 ATOM 5814 O O . GLU B 1 324 ? -39.849 22.852 30.507 1.00 28.02 ? 297 GLU B O 1 ATOM 5815 C CB . GLU B 1 324 ? -38.901 21.515 33.291 1.00 36.83 ? 297 GLU B CB 1 ATOM 5816 C CG . GLU B 1 324 ? -38.012 22.695 33.096 1.00 44.86 ? 297 GLU B CG 1 ATOM 5817 C CD . GLU B 1 324 ? -37.074 22.513 31.933 1.00 50.56 ? 297 GLU B CD 1 ATOM 5818 O OE1 . GLU B 1 324 ? -36.725 21.349 31.630 1.00 55.41 ? 297 GLU B OE1 1 ATOM 5819 O OE2 . GLU B 1 324 ? -36.697 23.542 31.320 1.00 56.30 ? 297 GLU B OE2 1 ATOM 5820 N N . ALA B 1 325 ? -39.859 20.622 30.257 1.00 28.05 ? 298 ALA B N 1 ATOM 5821 C CA . ALA B 1 325 ? -39.591 20.696 28.826 1.00 27.71 ? 298 ALA B CA 1 ATOM 5822 C C . ALA B 1 325 ? -40.753 21.252 28.011 1.00 28.50 ? 298 ALA B C 1 ATOM 5823 O O . ALA B 1 325 ? -40.509 21.871 26.982 1.00 32.67 ? 298 ALA B O 1 ATOM 5824 C CB . ALA B 1 325 ? -39.184 19.345 28.270 1.00 26.81 ? 298 ALA B CB 1 ATOM 5825 N N . TRP B 1 326 ? -41.993 21.061 28.456 1.00 27.06 ? 299 TRP B N 1 ATOM 5826 C CA . TRP B 1 326 ? -43.116 21.679 27.738 1.00 28.38 ? 299 TRP B CA 1 ATOM 5827 C C . TRP B 1 326 ? -43.807 22.802 28.475 1.00 29.94 ? 299 TRP B C 1 ATOM 5828 O O . TRP B 1 326 ? -44.616 23.503 27.875 1.00 31.09 ? 299 TRP B O 1 ATOM 5829 C CB . TRP B 1 326 ? -44.129 20.648 27.272 1.00 29.51 ? 299 TRP B CB 1 ATOM 5830 C CG . TRP B 1 326 ? -45.080 20.078 28.297 1.00 28.28 ? 299 TRP B CG 1 ATOM 5831 C CD1 . TRP B 1 326 ? -44.878 18.989 29.069 1.00 30.46 ? 299 TRP B CD1 1 ATOM 5832 C CD2 . TRP B 1 326 ? -46.419 20.512 28.556 1.00 29.52 ? 299 TRP B CD2 1 ATOM 5833 N NE1 . TRP B 1 326 ? -46.002 18.718 29.825 1.00 30.67 ? 299 TRP B NE1 1 ATOM 5834 C CE2 . TRP B 1 326 ? -46.963 19.642 29.522 1.00 29.49 ? 299 TRP B CE2 1 ATOM 5835 C CE3 . TRP B 1 326 ? -47.215 21.565 28.067 1.00 29.29 ? 299 TRP B CE3 1 ATOM 5836 C CZ2 . TRP B 1 326 ? -48.253 19.803 30.026 1.00 30.01 ? 299 TRP B CZ2 1 ATOM 5837 C CZ3 . TRP B 1 326 ? -48.496 21.718 28.557 1.00 28.02 ? 299 TRP B CZ3 1 ATOM 5838 C CH2 . TRP B 1 326 ? -49.009 20.840 29.522 1.00 29.22 ? 299 TRP B CH2 1 ATOM 5839 N N . ALA B 1 327 ? -43.465 23.010 29.749 1.00 32.10 ? 300 ALA B N 1 ATOM 5840 C CA . ALA B 1 327 ? -44.124 24.042 30.556 1.00 31.67 ? 300 ALA B CA 1 ATOM 5841 C C . ALA B 1 327 ? -43.879 25.442 30.007 1.00 34.48 ? 300 ALA B C 1 ATOM 5842 O O . ALA B 1 327 ? -44.638 26.364 30.329 1.00 32.44 ? 300 ALA B O 1 ATOM 5843 C CB . ALA B 1 327 ? -43.685 23.961 32.004 1.00 31.35 ? 300 ALA B CB 1 ATOM 5844 N N . SER B 1 328 ? -42.832 25.608 29.184 1.00 33.56 ? 301 SER B N 1 ATOM 5845 C CA . SER B 1 328 ? -42.571 26.900 28.507 1.00 32.68 ? 301 SER B CA 1 ATOM 5846 C C . SER B 1 328 ? -42.507 26.752 26.995 1.00 31.57 ? 301 SER B C 1 ATOM 5847 O O . SER B 1 328 ? -41.923 27.583 26.341 1.00 33.37 ? 301 SER B O 1 ATOM 5848 C CB . SER B 1 328 ? -41.255 27.512 28.983 1.00 31.55 ? 301 SER B CB 1 ATOM 5849 O OG . SER B 1 328 ? -41.219 27.562 30.382 1.00 36.65 ? 301 SER B OG 1 ATOM 5850 N N . SER B 1 329 ? -43.092 25.700 26.440 1.00 32.54 ? 302 SER B N 1 ATOM 5851 C CA . SER B 1 329 ? -42.927 25.433 25.026 1.00 34.67 ? 302 SER B CA 1 ATOM 5852 C C . SER B 1 329 ? -43.910 26.241 24.198 1.00 35.43 ? 302 SER B C 1 ATOM 5853 O O . SER B 1 329 ? -45.115 26.135 24.407 1.00 38.07 ? 302 SER B O 1 ATOM 5854 C CB . SER B 1 329 ? -43.134 23.957 24.740 1.00 32.70 ? 302 SER B CB 1 ATOM 5855 O OG . SER B 1 329 ? -43.254 23.752 23.357 1.00 34.14 ? 302 SER B OG 1 ATOM 5856 N N . SER B 1 330 ? -43.388 26.975 23.215 1.00 34.67 ? 303 SER B N 1 ATOM 5857 C CA . SER B 1 330 ? -44.193 27.782 22.297 1.00 35.64 ? 303 SER B CA 1 ATOM 5858 C C . SER B 1 330 ? -45.066 26.943 21.373 1.00 36.52 ? 303 SER B C 1 ATOM 5859 O O . SER B 1 330 ? -46.026 27.441 20.798 1.00 36.55 ? 303 SER B O 1 ATOM 5860 C CB . SER B 1 330 ? -43.290 28.698 21.462 1.00 35.64 ? 303 SER B CB 1 ATOM 5861 O OG . SER B 1 330 ? -42.555 27.948 20.517 1.00 37.45 ? 303 SER B OG 1 ATOM 5862 N N . LEU B 1 331 ? -44.741 25.668 21.224 1.00 37.52 ? 304 LEU B N 1 ATOM 5863 C CA . LEU B 1 331 ? -45.567 24.758 20.434 1.00 35.18 ? 304 LEU B CA 1 ATOM 5864 C C . LEU B 1 331 ? -46.885 24.423 21.109 1.00 34.55 ? 304 LEU B C 1 ATOM 5865 O O . LEU B 1 331 ? -47.857 24.027 20.449 1.00 31.83 ? 304 LEU B O 1 ATOM 5866 C CB . LEU B 1 331 ? -44.821 23.452 20.170 1.00 35.25 ? 304 LEU B CB 1 ATOM 5867 C CG . LEU B 1 331 ? -43.532 23.621 19.364 1.00 37.24 ? 304 LEU B CG 1 ATOM 5868 C CD1 . LEU B 1 331 ? -42.803 22.298 19.268 1.00 37.51 ? 304 LEU B CD1 1 ATOM 5869 C CD2 . LEU B 1 331 ? -43.859 24.163 17.971 1.00 38.55 ? 304 LEU B CD2 1 ATOM 5870 N N . ILE B 1 332 ? -46.911 24.532 22.429 1.00 34.96 ? 305 ILE B N 1 ATOM 5871 C CA . ILE B 1 332 ? -48.087 24.151 23.199 1.00 32.44 ? 305 ILE B CA 1 ATOM 5872 C C . ILE B 1 332 ? -48.792 25.374 23.764 1.00 33.38 ? 305 ILE B C 1 ATOM 5873 O O . ILE B 1 332 ? -50.020 25.406 23.803 1.00 36.39 ? 305 ILE B O 1 ATOM 5874 C CB . ILE B 1 332 ? -47.715 23.208 24.337 1.00 32.13 ? 305 ILE B CB 1 ATOM 5875 C CG1 . ILE B 1 332 ? -46.835 22.044 23.823 1.00 32.44 ? 305 ILE B CG1 1 ATOM 5876 C CG2 . ILE B 1 332 ? -48.971 22.712 25.024 1.00 32.10 ? 305 ILE B CG2 1 ATOM 5877 C CD1 . ILE B 1 332 ? -47.487 21.095 22.837 1.00 31.73 ? 305 ILE B CD1 1 ATOM 5878 N N . ALA B 1 333 ? -48.034 26.383 24.172 1.00 31.92 ? 306 ALA B N 1 ATOM 5879 C CA . ALA B 1 333 ? -48.615 27.602 24.745 1.00 34.88 ? 306 ALA B CA 1 ATOM 5880 C C . ALA B 1 333 ? -49.078 28.552 23.643 1.00 37.03 ? 306 ALA B C 1 ATOM 5881 O O . ALA B 1 333 ? -48.486 29.605 23.415 1.00 37.12 ? 306 ALA B O 1 ATOM 5882 C CB . ALA B 1 333 ? -47.609 28.299 25.656 1.00 34.81 ? 306 ALA B CB 1 ATOM 5883 N N . MET B 1 334 ? -50.143 28.168 22.963 1.00 39.43 ? 307 MET B N 1 ATOM 5884 C CA . MET B 1 334 ? -50.671 28.945 21.851 1.00 41.75 ? 307 MET B CA 1 ATOM 5885 C C . MET B 1 334 ? -52.077 29.396 22.178 1.00 42.08 ? 307 MET B C 1 ATOM 5886 O O . MET B 1 334 ? -52.889 28.585 22.640 1.00 37.66 ? 307 MET B O 1 ATOM 5887 C CB . MET B 1 334 ? -50.660 28.104 20.593 1.00 44.88 ? 307 MET B CB 1 ATOM 5888 C CG . MET B 1 334 ? -49.243 27.767 20.172 1.00 46.96 ? 307 MET B CG 1 ATOM 5889 S SD . MET B 1 334 ? -49.152 27.367 18.444 1.00 54.42 ? 307 MET B SD 1 ATOM 5890 C CE . MET B 1 334 ? -49.363 29.014 17.766 1.00 55.67 ? 307 MET B CE 1 ATOM 5891 N N . PRO B 1 335 ? -52.366 30.687 21.950 1.00 45.07 ? 308 PRO B N 1 ATOM 5892 C CA . PRO B 1 335 ? -53.674 31.255 22.287 1.00 47.17 ? 308 PRO B CA 1 ATOM 5893 C C . PRO B 1 335 ? -54.858 30.393 21.833 1.00 41.40 ? 308 PRO B C 1 ATOM 5894 O O . PRO B 1 335 ? -55.794 30.211 22.586 1.00 45.50 ? 308 PRO B O 1 ATOM 5895 C CB . PRO B 1 335 ? -53.664 32.608 21.560 1.00 48.30 ? 308 PRO B CB 1 ATOM 5896 C CG . PRO B 1 335 ? -52.221 32.991 21.535 1.00 49.82 ? 308 PRO B CG 1 ATOM 5897 C CD . PRO B 1 335 ? -51.488 31.690 21.314 1.00 48.35 ? 308 PRO B CD 1 ATOM 5898 N N . GLN B 1 336 ? -54.806 29.832 20.642 1.00 41.59 ? 309 GLN B N 1 ATOM 5899 C CA . GLN B 1 336 ? -55.934 29.033 20.162 1.00 46.86 ? 309 GLN B CA 1 ATOM 5900 C C . GLN B 1 336 ? -56.100 27.667 20.823 1.00 45.28 ? 309 GLN B C 1 ATOM 5901 O O . GLN B 1 336 ? -57.084 26.973 20.555 1.00 45.71 ? 309 GLN B O 1 ATOM 5902 C CB . GLN B 1 336 ? -55.904 28.872 18.634 1.00 50.89 ? 309 GLN B CB 1 ATOM 5903 C CG . GLN B 1 336 ? -54.863 27.926 18.103 1.00 51.85 ? 309 GLN B CG 1 ATOM 5904 C CD . GLN B 1 336 ? -53.549 28.601 17.827 1.00 58.53 ? 309 GLN B CD 1 ATOM 5905 O OE1 . GLN B 1 336 ? -53.214 29.655 18.406 1.00 58.41 ? 309 GLN B OE1 1 ATOM 5906 N NE2 . GLN B 1 336 ? -52.771 27.987 16.947 1.00 61.26 ? 309 GLN B NE2 1 ATOM 5907 N N . TYR B 1 337 ? -55.158 27.273 21.684 1.00 42.22 ? 310 TYR B N 1 ATOM 5908 C CA . TYR B 1 337 ? -55.338 26.083 22.505 1.00 38.76 ? 310 TYR B CA 1 ATOM 5909 C C . TYR B 1 337 ? -55.778 26.430 23.930 1.00 38.35 ? 310 TYR B C 1 ATOM 5910 O O . TYR B 1 337 ? -55.936 25.532 24.756 1.00 40.62 ? 310 TYR B O 1 ATOM 5911 C CB . TYR B 1 337 ? -54.046 25.294 22.610 1.00 40.22 ? 310 TYR B CB 1 ATOM 5912 C CG . TYR B 1 337 ? -53.379 24.875 21.322 1.00 41.40 ? 310 TYR B CG 1 ATOM 5913 C CD1 . TYR B 1 337 ? -54.090 24.724 20.124 1.00 46.07 ? 310 TYR B CD1 1 ATOM 5914 C CD2 . TYR B 1 337 ? -52.031 24.582 21.313 1.00 39.52 ? 310 TYR B CD2 1 ATOM 5915 C CE1 . TYR B 1 337 ? -53.454 24.311 18.962 1.00 42.00 ? 310 TYR B CE1 1 ATOM 5916 C CE2 . TYR B 1 337 ? -51.392 24.175 20.165 1.00 40.13 ? 310 TYR B CE2 1 ATOM 5917 C CZ . TYR B 1 337 ? -52.102 24.045 18.998 1.00 41.40 ? 310 TYR B CZ 1 ATOM 5918 O OH . TYR B 1 337 ? -51.445 23.618 17.889 1.00 38.32 ? 310 TYR B OH 1 ATOM 5919 N N . PHE B 1 338 ? -55.970 27.710 24.238 1.00 36.61 ? 311 PHE B N 1 ATOM 5920 C CA . PHE B 1 338 ? -56.066 28.132 25.635 1.00 39.16 ? 311 PHE B CA 1 ATOM 5921 C C . PHE B 1 338 ? -57.282 27.572 26.352 1.00 39.61 ? 311 PHE B C 1 ATOM 5922 O O . PHE B 1 338 ? -57.268 27.375 27.574 1.00 37.72 ? 311 PHE B O 1 ATOM 5923 C CB . PHE B 1 338 ? -56.050 29.655 25.761 1.00 41.66 ? 311 PHE B CB 1 ATOM 5924 C CG . PHE B 1 338 ? -55.828 30.137 27.167 1.00 43.68 ? 311 PHE B CG 1 ATOM 5925 C CD1 . PHE B 1 338 ? -54.543 30.259 27.676 1.00 45.34 ? 311 PHE B CD1 1 ATOM 5926 C CD2 . PHE B 1 338 ? -56.903 30.445 27.990 1.00 46.34 ? 311 PHE B CD2 1 ATOM 5927 C CE1 . PHE B 1 338 ? -54.331 30.692 28.975 1.00 46.79 ? 311 PHE B CE1 1 ATOM 5928 C CE2 . PHE B 1 338 ? -56.700 30.885 29.299 1.00 45.20 ? 311 PHE B CE2 1 ATOM 5929 C CZ . PHE B 1 338 ? -55.414 31.007 29.790 1.00 46.36 ? 311 PHE B CZ 1 ATOM 5930 N N . HIS B 1 339 ? -58.327 27.300 25.589 1.00 40.60 ? 312 HIS B N 1 ATOM 5931 C CA . HIS B 1 339 ? -59.535 26.728 26.142 1.00 42.79 ? 312 HIS B CA 1 ATOM 5932 C C . HIS B 1 339 ? -59.328 25.299 26.649 1.00 42.00 ? 312 HIS B C 1 ATOM 5933 O O . HIS B 1 339 ? -60.111 24.812 27.461 1.00 42.07 ? 312 HIS B O 1 ATOM 5934 C CB . HIS B 1 339 ? -60.720 26.834 25.141 1.00 46.13 ? 312 HIS B CB 1 ATOM 5935 C CG . HIS B 1 339 ? -60.547 26.045 23.874 1.00 48.81 ? 312 HIS B CG 1 ATOM 5936 N ND1 . HIS B 1 339 ? -59.692 26.424 22.862 1.00 50.94 ? 312 HIS B ND1 1 ATOM 5937 C CD2 . HIS B 1 339 ? -61.164 24.921 23.439 1.00 50.79 ? 312 HIS B CD2 1 ATOM 5938 C CE1 . HIS B 1 339 ? -59.768 25.551 21.872 1.00 53.14 ? 312 HIS B CE1 1 ATOM 5939 N NE2 . HIS B 1 339 ? -60.662 24.633 22.193 1.00 52.05 ? 312 HIS B NE2 1 ATOM 5940 N N . VAL B 1 340 ? -58.283 24.627 26.168 1.00 41.24 ? 313 VAL B N 1 ATOM 5941 C CA . VAL B 1 340 ? -57.893 23.300 26.681 1.00 42.82 ? 313 VAL B CA 1 ATOM 5942 C C . VAL B 1 340 ? -56.722 23.390 27.685 1.00 39.55 ? 313 VAL B C 1 ATOM 5943 O O . VAL B 1 340 ? -56.669 22.686 28.678 1.00 37.02 ? 313 VAL B O 1 ATOM 5944 C CB . VAL B 1 340 ? -57.501 22.370 25.507 1.00 45.74 ? 313 VAL B CB 1 ATOM 5945 C CG1 . VAL B 1 340 ? -56.827 21.087 25.990 1.00 46.62 ? 313 VAL B CG1 1 ATOM 5946 C CG2 . VAL B 1 340 ? -58.732 22.033 24.684 1.00 48.11 ? 313 VAL B CG2 1 ATOM 5947 N N . VAL B 1 341 ? -55.804 24.286 27.402 1.00 36.55 ? 314 VAL B N 1 ATOM 5948 C CA . VAL B 1 341 ? -54.479 24.269 27.978 1.00 38.26 ? 314 VAL B CA 1 ATOM 5949 C C . VAL B 1 341 ? -54.308 25.389 29.017 1.00 39.19 ? 314 VAL B C 1 ATOM 5950 O O . VAL B 1 341 ? -53.360 25.395 29.809 1.00 36.12 ? 314 VAL B O 1 ATOM 5951 C CB . VAL B 1 341 ? -53.491 24.321 26.776 1.00 39.61 ? 314 VAL B CB 1 ATOM 5952 C CG1 . VAL B 1 341 ? -52.699 25.601 26.736 1.00 40.81 ? 314 VAL B CG1 1 ATOM 5953 C CG2 . VAL B 1 341 ? -52.667 23.058 26.701 1.00 41.90 ? 314 VAL B CG2 1 ATOM 5954 N N . GLY B 1 342 ? -55.258 26.325 29.048 1.00 36.34 ? 315 GLY B N 1 ATOM 5955 C CA . GLY B 1 342 ? -55.232 27.396 30.025 1.00 34.29 ? 315 GLY B CA 1 ATOM 5956 C C . GLY B 1 342 ? -55.193 26.887 31.446 1.00 32.37 ? 315 GLY B C 1 ATOM 5957 O O . GLY B 1 342 ? -55.828 25.902 31.784 1.00 33.31 ? 315 GLY B O 1 ATOM 5958 N N . GLY B 1 343 ? -54.417 27.571 32.279 1.00 33.82 ? 316 GLY B N 1 ATOM 5959 C CA . GLY B 1 343 ? -54.261 27.213 33.673 1.00 32.23 ? 316 GLY B CA 1 ATOM 5960 C C . GLY B 1 343 ? -53.299 26.081 33.981 1.00 31.40 ? 316 GLY B C 1 ATOM 5961 O O . GLY B 1 343 ? -53.196 25.690 35.154 1.00 29.29 ? 316 GLY B O 1 ATOM 5962 N N . THR B 1 344 ? -52.556 25.585 32.985 1.00 32.69 ? 317 THR B N 1 ATOM 5963 C CA . THR B 1 344 ? -51.568 24.537 33.282 1.00 32.65 ? 317 THR B CA 1 ATOM 5964 C C . THR B 1 344 ? -50.598 25.062 34.348 1.00 30.96 ? 317 THR B C 1 ATOM 5965 O O . THR B 1 344 ? -50.236 26.233 34.376 1.00 29.94 ? 317 THR B O 1 ATOM 5966 C CB . THR B 1 344 ? -50.799 23.846 32.088 1.00 32.51 ? 317 THR B CB 1 ATOM 5967 O OG1 . THR B 1 344 ? -49.420 24.223 32.008 1.00 38.81 ? 317 THR B OG1 1 ATOM 5968 C CG2 . THR B 1 344 ? -51.455 23.978 30.793 1.00 29.24 ? 317 THR B CG2 1 ATOM 5969 N N . ILE B 1 345 ? -50.185 24.166 35.216 1.00 29.17 ? 318 ILE B N 1 ATOM 5970 C CA . ILE B 1 345 ? -49.177 24.462 36.220 1.00 30.90 ? 318 ILE B CA 1 ATOM 5971 C C . ILE B 1 345 ? -47.949 23.652 35.827 1.00 31.54 ? 318 ILE B C 1 ATOM 5972 O O . ILE B 1 345 ? -48.075 22.476 35.538 1.00 30.46 ? 318 ILE B O 1 ATOM 5973 C CB . ILE B 1 345 ? -49.650 24.041 37.608 1.00 32.28 ? 318 ILE B CB 1 ATOM 5974 C CG1 . ILE B 1 345 ? -50.841 24.905 38.021 1.00 37.66 ? 318 ILE B CG1 1 ATOM 5975 C CG2 . ILE B 1 345 ? -48.532 24.175 38.632 1.00 34.41 ? 318 ILE B CG2 1 ATOM 5976 C CD1 . ILE B 1 345 ? -51.697 24.289 39.106 1.00 40.22 ? 318 ILE B CD1 1 ATOM 5977 N N . GLY B 1 346 ? -46.769 24.264 35.860 1.00 32.46 ? 319 GLY B N 1 ATOM 5978 C CA . GLY B 1 346 ? -45.559 23.583 35.431 1.00 34.93 ? 319 GLY B CA 1 ATOM 5979 C C . GLY B 1 346 ? -44.289 24.005 36.140 1.00 36.34 ? 319 GLY B C 1 ATOM 5980 O O . GLY B 1 346 ? -44.271 24.926 36.961 1.00 36.28 ? 319 GLY B O 1 ATOM 5981 N N . PHE B 1 347 ? -43.205 23.328 35.795 1.00 36.42 ? 320 PHE B N 1 ATOM 5982 C CA . PHE B 1 347 ? -41.915 23.612 36.387 1.00 35.49 ? 320 PHE B CA 1 ATOM 5983 C C . PHE B 1 347 ? -41.093 24.366 35.393 1.00 33.45 ? 320 PHE B C 1 ATOM 5984 O O . PHE B 1 347 ? -41.272 24.252 34.184 1.00 34.42 ? 320 PHE B O 1 ATOM 5985 C CB . PHE B 1 347 ? -41.238 22.332 36.823 1.00 36.94 ? 320 PHE B CB 1 ATOM 5986 C CG . PHE B 1 347 ? -41.949 21.669 37.939 1.00 37.45 ? 320 PHE B CG 1 ATOM 5987 C CD1 . PHE B 1 347 ? -41.674 22.015 39.258 1.00 40.71 ? 320 PHE B CD1 1 ATOM 5988 C CD2 . PHE B 1 347 ? -42.961 20.783 37.682 1.00 39.95 ? 320 PHE B CD2 1 ATOM 5989 C CE1 . PHE B 1 347 ? -42.374 21.441 40.305 1.00 40.02 ? 320 PHE B CE1 1 ATOM 5990 C CE2 . PHE B 1 347 ? -43.670 20.207 38.720 1.00 36.92 ? 320 PHE B CE2 1 ATOM 5991 C CZ . PHE B 1 347 ? -43.368 20.526 40.029 1.00 38.91 ? 320 PHE B CZ 1 ATOM 5992 N N . ALA B 1 348 ? -40.232 25.208 35.919 1.00 32.56 ? 321 ALA B N 1 ATOM 5993 C CA . ALA B 1 348 ? -39.332 25.969 35.113 1.00 34.37 ? 321 ALA B CA 1 ATOM 5994 C C . ALA B 1 348 ? -38.109 25.993 35.973 1.00 37.31 ? 321 ALA B C 1 ATOM 5995 O O . ALA B 1 348 ? -38.196 25.879 37.193 1.00 36.79 ? 321 ALA B O 1 ATOM 5996 C CB . ALA B 1 348 ? -39.852 27.362 34.877 1.00 35.10 ? 321 ALA B CB 1 ATOM 5997 N N . LEU B 1 349 ? -36.966 26.113 35.342 1.00 38.78 ? 322 LEU B N 1 ATOM 5998 C CA . LEU B 1 349 ? -35.737 26.244 36.088 1.00 41.23 ? 322 LEU B CA 1 ATOM 5999 C C . LEU B 1 349 ? -35.600 27.644 36.594 1.00 40.18 ? 322 LEU B C 1 ATOM 6000 O O . LEU B 1 349 ? -36.325 28.532 36.147 1.00 42.75 ? 322 LEU B O 1 ATOM 6001 C CB . LEU B 1 349 ? -34.589 25.953 35.171 1.00 43.48 ? 322 LEU B CB 1 ATOM 6002 C CG . LEU B 1 349 ? -34.059 24.541 35.023 1.00 44.44 ? 322 LEU B CG 1 ATOM 6003 C CD1 . LEU B 1 349 ? -34.867 23.401 35.614 1.00 47.90 ? 322 LEU B CD1 1 ATOM 6004 C CD2 . LEU B 1 349 ? -33.861 24.343 33.541 1.00 46.17 ? 322 LEU B CD2 1 ATOM 6005 N N . LYS B 1 350 ? -34.687 27.850 37.535 1.00 40.04 ? 323 LYS B N 1 ATOM 6006 C CA . LYS B 1 350 ? -34.461 29.190 38.055 1.00 41.84 ? 323 LYS B CA 1 ATOM 6007 C C . LYS B 1 350 ? -33.893 30.066 36.940 1.00 38.40 ? 323 LYS B C 1 ATOM 6008 O O . LYS B 1 350 ? -33.031 29.645 36.184 1.00 37.51 ? 323 LYS B O 1 ATOM 6009 C CB . LYS B 1 350 ? -33.557 29.174 39.301 1.00 43.96 ? 323 LYS B CB 1 ATOM 6010 C CG . LYS B 1 350 ? -34.258 28.698 40.579 1.00 49.84 ? 323 LYS B CG 1 ATOM 6011 C CD . LYS B 1 350 ? -35.639 29.359 40.790 1.00 53.00 ? 323 LYS B CD 1 ATOM 6012 C CE . LYS B 1 350 ? -35.999 29.709 42.212 1.00 57.33 ? 323 LYS B CE 1 ATOM 6013 N NZ . LYS B 1 350 ? -35.990 28.579 43.169 1.00 62.86 ? 323 LYS B NZ 1 ATOM 6014 N N . ALA B 1 351 ? -34.414 31.278 36.822 1.00 38.38 ? 324 ALA B N 1 ATOM 6015 C CA . ALA B 1 351 ? -33.901 32.228 35.863 1.00 37.37 ? 324 ALA B CA 1 ATOM 6016 C C . ALA B 1 351 ? -32.537 32.721 36.301 1.00 39.17 ? 324 ALA B C 1 ATOM 6017 O O . ALA B 1 351 ? -32.227 32.764 37.489 1.00 43.03 ? 324 ALA B O 1 ATOM 6018 C CB . ALA B 1 351 ? -34.857 33.392 35.717 1.00 40.06 ? 324 ALA B CB 1 ATOM 6019 N N . GLY B 1 352 ? -31.714 33.072 35.326 1.00 39.08 ? 325 GLY B N 1 ATOM 6020 C CA . GLY B 1 352 ? -30.412 33.649 35.575 1.00 39.22 ? 325 GLY B CA 1 ATOM 6021 C C . GLY B 1 352 ? -30.308 34.907 34.749 1.00 42.83 ? 325 GLY B C 1 ATOM 6022 O O . GLY B 1 352 ? -31.140 35.135 33.870 1.00 42.02 ? 325 GLY B O 1 ATOM 6023 N N . GLN B 1 353 ? -29.309 35.737 35.036 1.00 41.95 ? 326 GLN B N 1 ATOM 6024 C CA . GLN B 1 353 ? -29.126 36.940 34.266 1.00 45.43 ? 326 GLN B CA 1 ATOM 6025 C C . GLN B 1 353 ? -27.852 36.907 33.463 1.00 42.56 ? 326 GLN B C 1 ATOM 6026 O O . GLN B 1 353 ? -26.846 36.353 33.886 1.00 41.92 ? 326 GLN B O 1 ATOM 6027 C CB . GLN B 1 353 ? -29.184 38.155 35.179 1.00 54.54 ? 326 GLN B CB 1 ATOM 6028 C CG . GLN B 1 353 ? -30.579 38.757 35.219 1.00 62.91 ? 326 GLN B CG 1 ATOM 6029 C CD . GLN B 1 353 ? -30.996 39.130 36.614 1.00 73.80 ? 326 GLN B CD 1 ATOM 6030 O OE1 . GLN B 1 353 ? -30.213 39.712 37.370 1.00 81.94 ? 326 GLN B OE1 1 ATOM 6031 N NE2 . GLN B 1 353 ? -32.237 38.794 36.975 1.00 77.99 ? 326 GLN B NE2 1 ATOM 6032 N N . ILE B 1 354 ? -27.921 37.476 32.267 1.00 38.58 ? 327 ILE B N 1 ATOM 6033 C CA . ILE B 1 354 ? -26.761 37.625 31.423 1.00 39.82 ? 327 ILE B CA 1 ATOM 6034 C C . ILE B 1 354 ? -26.775 39.063 30.903 1.00 41.70 ? 327 ILE B C 1 ATOM 6035 O O . ILE B 1 354 ? -27.425 39.356 29.886 1.00 38.24 ? 327 ILE B O 1 ATOM 6036 C CB . ILE B 1 354 ? -26.764 36.658 30.223 1.00 39.87 ? 327 ILE B CB 1 ATOM 6037 C CG1 . ILE B 1 354 ? -27.100 35.225 30.661 1.00 42.83 ? 327 ILE B CG1 1 ATOM 6038 C CG2 . ILE B 1 354 ? -25.413 36.716 29.538 1.00 39.10 ? 327 ILE B CG2 1 ATOM 6039 C CD1 . ILE B 1 354 ? -27.202 34.254 29.503 1.00 45.09 ? 327 ILE B CD1 1 ATOM 6040 N N . PRO B 1 355 ? -26.079 39.968 31.609 1.00 42.59 ? 328 PRO B N 1 ATOM 6041 C CA . PRO B 1 355 ? -26.011 41.355 31.147 1.00 41.03 ? 328 PRO B CA 1 ATOM 6042 C C . PRO B 1 355 ? -25.424 41.476 29.759 1.00 40.78 ? 328 PRO B C 1 ATOM 6043 O O . PRO B 1 355 ? -24.371 40.908 29.482 1.00 41.38 ? 328 PRO B O 1 ATOM 6044 C CB . PRO B 1 355 ? -25.084 42.022 32.182 1.00 41.03 ? 328 PRO B CB 1 ATOM 6045 C CG . PRO B 1 355 ? -25.324 41.232 33.433 1.00 42.52 ? 328 PRO B CG 1 ATOM 6046 C CD . PRO B 1 355 ? -25.512 39.807 32.965 1.00 41.24 ? 328 PRO B CD 1 ATOM 6047 N N . GLY B 1 356 ? -26.119 42.202 28.883 1.00 43.64 ? 329 GLY B N 1 ATOM 6048 C CA . GLY B 1 356 ? -25.632 42.456 27.531 1.00 41.55 ? 329 GLY B CA 1 ATOM 6049 C C . GLY B 1 356 ? -26.105 41.429 26.521 1.00 44.17 ? 329 GLY B C 1 ATOM 6050 O O . GLY B 1 356 ? -25.830 41.571 25.327 1.00 45.73 ? 329 GLY B O 1 ATOM 6051 N N . PHE B 1 357 ? -26.812 40.387 26.966 1.00 43.59 ? 330 PHE B N 1 ATOM 6052 C CA . PHE B 1 357 ? -27.130 39.282 26.045 1.00 41.48 ? 330 PHE B CA 1 ATOM 6053 C C . PHE B 1 357 ? -28.235 39.737 25.100 1.00 39.32 ? 330 PHE B C 1 ATOM 6054 O O . PHE B 1 357 ? -28.120 39.586 23.897 1.00 41.61 ? 330 PHE B O 1 ATOM 6055 C CB . PHE B 1 357 ? -27.533 38.016 26.806 1.00 37.74 ? 330 PHE B CB 1 ATOM 6056 C CG . PHE B 1 357 ? -27.907 36.847 25.919 1.00 33.71 ? 330 PHE B CG 1 ATOM 6057 C CD1 . PHE B 1 357 ? -27.065 36.406 24.935 1.00 34.10 ? 330 PHE B CD1 1 ATOM 6058 C CD2 . PHE B 1 357 ? -29.093 36.169 26.113 1.00 33.30 ? 330 PHE B CD2 1 ATOM 6059 C CE1 . PHE B 1 357 ? -27.401 35.332 24.134 1.00 31.98 ? 330 PHE B CE1 1 ATOM 6060 C CE2 . PHE B 1 357 ? -29.440 35.090 25.316 1.00 33.32 ? 330 PHE B CE2 1 ATOM 6061 C CZ . PHE B 1 357 ? -28.575 34.664 24.331 1.00 30.72 ? 330 PHE B CZ 1 ATOM 6062 N N . ARG B 1 358 ? -29.280 40.324 25.645 1.00 41.83 ? 331 ARG B N 1 ATOM 6063 C CA . ARG B 1 358 ? -30.358 40.857 24.806 1.00 47.78 ? 331 ARG B CA 1 ATOM 6064 C C . ARG B 1 358 ? -29.865 41.792 23.682 1.00 48.54 ? 331 ARG B C 1 ATOM 6065 O O . ARG B 1 358 ? -30.303 41.676 22.533 1.00 48.19 ? 331 ARG B O 1 ATOM 6066 C CB . ARG B 1 358 ? -31.380 41.569 25.672 1.00 48.76 ? 331 ARG B CB 1 ATOM 6067 C CG . ARG B 1 358 ? -32.578 42.029 24.877 1.00 52.81 ? 331 ARG B CG 1 ATOM 6068 C CD . ARG B 1 358 ? -33.725 42.426 25.768 1.00 52.23 ? 331 ARG B CD 1 ATOM 6069 N NE . ARG B 1 358 ? -34.949 42.096 25.075 1.00 58.34 ? 331 ARG B NE 1 ATOM 6070 C CZ . ARG B 1 358 ? -35.766 41.096 25.385 1.00 62.70 ? 331 ARG B CZ 1 ATOM 6071 N NH1 . ARG B 1 358 ? -35.552 40.311 26.434 1.00 62.00 ? 331 ARG B NH1 1 ATOM 6072 N NH2 . ARG B 1 358 ? -36.850 40.915 24.646 1.00 66.91 ? 331 ARG B NH2 1 ATOM 6073 N N . GLU B 1 359 ? -28.926 42.677 24.005 1.00 47.78 ? 332 GLU B N 1 ATOM 6074 C CA . GLU B 1 359 ? -28.354 43.604 23.020 1.00 47.37 ? 332 GLU B CA 1 ATOM 6075 C C . GLU B 1 359 ? -27.533 42.850 21.974 1.00 49.38 ? 332 GLU B C 1 ATOM 6076 O O . GLU B 1 359 ? -27.577 43.168 20.778 1.00 48.73 ? 332 GLU B O 1 ATOM 6077 C CB . GLU B 1 359 ? -27.480 44.672 23.710 1.00 46.62 ? 332 GLU B CB 1 ATOM 6078 N N . PHE B 1 360 ? -26.775 41.853 22.420 1.00 43.00 ? 333 PHE B N 1 ATOM 6079 C CA . PHE B 1 360 ? -26.051 40.983 21.496 1.00 43.18 ? 333 PHE B CA 1 ATOM 6080 C C . PHE B 1 360 ? -27.007 40.289 20.510 1.00 43.53 ? 333 PHE B C 1 ATOM 6081 O O . PHE B 1 360 ? -26.744 40.200 19.305 1.00 42.64 ? 333 PHE B O 1 ATOM 6082 C CB . PHE B 1 360 ? -25.277 39.933 22.288 1.00 39.97 ? 333 PHE B CB 1 ATOM 6083 C CG . PHE B 1 360 ? -24.605 38.914 21.439 1.00 38.46 ? 333 PHE B CG 1 ATOM 6084 C CD1 . PHE B 1 360 ? -23.414 39.200 20.814 1.00 36.75 ? 333 PHE B CD1 1 ATOM 6085 C CD2 . PHE B 1 360 ? -25.169 37.647 21.270 1.00 35.74 ? 333 PHE B CD2 1 ATOM 6086 C CE1 . PHE B 1 360 ? -22.782 38.252 20.033 1.00 37.03 ? 333 PHE B CE1 1 ATOM 6087 C CE2 . PHE B 1 360 ? -24.543 36.694 20.498 1.00 33.87 ? 333 PHE B CE2 1 ATOM 6088 C CZ . PHE B 1 360 ? -23.348 36.989 19.881 1.00 37.75 ? 333 PHE B CZ 1 ATOM 6089 N N . LEU B 1 361 ? -28.099 39.781 21.057 1.00 45.92 ? 334 LEU B N 1 ATOM 6090 C CA . LEU B 1 361 ? -29.135 39.106 20.282 1.00 46.72 ? 334 LEU B CA 1 ATOM 6091 C C . LEU B 1 361 ? -29.676 40.008 19.155 1.00 51.04 ? 334 LEU B C 1 ATOM 6092 O O . LEU B 1 361 ? -29.886 39.551 18.043 1.00 47.63 ? 334 LEU B O 1 ATOM 6093 C CB . LEU B 1 361 ? -30.290 38.698 21.206 1.00 45.26 ? 334 LEU B CB 1 ATOM 6094 C CG . LEU B 1 361 ? -30.507 37.248 21.655 1.00 46.98 ? 334 LEU B CG 1 ATOM 6095 C CD1 . LEU B 1 361 ? -29.249 36.398 21.629 1.00 47.58 ? 334 LEU B CD1 1 ATOM 6096 C CD2 . LEU B 1 361 ? -31.187 37.200 23.010 1.00 47.68 ? 334 LEU B CD2 1 ATOM 6097 N N . LYS B 1 362 ? -29.906 41.283 19.461 1.00 54.83 ? 335 LYS B N 1 ATOM 6098 C CA . LYS B 1 362 ? -30.428 42.239 18.472 1.00 57.31 ? 335 LYS B CA 1 ATOM 6099 C C . LYS B 1 362 ? -29.426 42.634 17.389 1.00 57.33 ? 335 LYS B C 1 ATOM 6100 O O . LYS B 1 362 ? -29.829 43.161 16.363 1.00 58.45 ? 335 LYS B O 1 ATOM 6101 C CB . LYS B 1 362 ? -30.979 43.475 19.167 1.00 57.22 ? 335 LYS B CB 1 ATOM 6102 C CG . LYS B 1 362 ? -32.292 43.203 19.875 1.00 59.67 ? 335 LYS B CG 1 ATOM 6103 C CD . LYS B 1 362 ? -32.550 44.207 20.977 1.00 61.45 ? 335 LYS B CD 1 ATOM 6104 C CE . LYS B 1 362 ? -33.972 44.109 21.487 1.00 65.66 ? 335 LYS B CE 1 ATOM 6105 N NZ . LYS B 1 362 ? -34.213 45.120 22.554 1.00 72.49 ? 335 LYS B NZ 1 ATOM 6106 N N . LYS B 1 363 ? -28.142 42.347 17.590 1.00 56.26 ? 336 LYS B N 1 ATOM 6107 C CA . LYS B 1 363 ? -27.136 42.612 16.566 1.00 54.24 ? 336 LYS B CA 1 ATOM 6108 C C . LYS B 1 363 ? -27.020 41.555 15.463 1.00 52.89 ? 336 LYS B C 1 ATOM 6109 O O . LYS B 1 363 ? -26.164 41.697 14.584 1.00 46.73 ? 336 LYS B O 1 ATOM 6110 C CB . LYS B 1 363 ? -25.764 42.798 17.219 1.00 62.14 ? 336 LYS B CB 1 ATOM 6111 C CG . LYS B 1 363 ? -25.668 44.017 18.134 1.00 64.87 ? 336 LYS B CG 1 ATOM 6112 C CD . LYS B 1 363 ? -24.466 43.942 19.075 1.00 68.20 ? 336 LYS B CD 1 ATOM 6113 C CE . LYS B 1 363 ? -23.161 43.639 18.347 1.00 70.88 ? 336 LYS B CE 1 ATOM 6114 N NZ . LYS B 1 363 ? -21.984 43.722 19.260 1.00 74.60 ? 336 LYS B NZ 1 ATOM 6115 N N . VAL B 1 364 ? -27.820 40.482 15.499 1.00 51.37 ? 337 VAL B N 1 ATOM 6116 C CA . VAL B 1 364 ? -27.675 39.434 14.461 1.00 51.98 ? 337 VAL B CA 1 ATOM 6117 C C . VAL B 1 364 ? -27.904 40.002 13.094 1.00 47.85 ? 337 VAL B C 1 ATOM 6118 O O . VAL B 1 364 ? -28.836 40.782 12.905 1.00 46.19 ? 337 VAL B O 1 ATOM 6119 C CB . VAL B 1 364 ? -28.731 38.295 14.431 1.00 49.35 ? 337 VAL B CB 1 ATOM 6120 C CG1 . VAL B 1 364 ? -28.028 36.971 14.216 1.00 49.90 ? 337 VAL B CG1 1 ATOM 6121 C CG2 . VAL B 1 364 ? -29.576 38.254 15.661 1.00 55.64 ? 337 VAL B CG2 1 ATOM 6122 N N . HIS B 1 365 ? -27.133 39.514 12.135 1.00 50.15 ? 338 HIS B N 1 ATOM 6123 C CA . HIS B 1 365 ? -27.304 39.950 10.770 1.00 53.34 ? 338 HIS B CA 1 ATOM 6124 C C . HIS B 1 365 ? -26.737 38.962 9.777 1.00 48.88 ? 338 HIS B C 1 ATOM 6125 O O . HIS B 1 365 ? -25.620 38.498 9.959 1.00 46.73 ? 338 HIS B O 1 ATOM 6126 C CB . HIS B 1 365 ? -26.627 41.296 10.563 1.00 58.44 ? 338 HIS B CB 1 ATOM 6127 C CG . HIS B 1 365 ? -27.232 42.084 9.452 1.00 62.50 ? 338 HIS B CG 1 ATOM 6128 N ND1 . HIS B 1 365 ? -28.363 42.846 9.630 1.00 65.42 ? 338 HIS B ND1 1 ATOM 6129 C CD2 . HIS B 1 365 ? -26.896 42.199 8.147 1.00 61.90 ? 338 HIS B CD2 1 ATOM 6130 C CE1 . HIS B 1 365 ? -28.687 43.416 8.487 1.00 66.18 ? 338 HIS B CE1 1 ATOM 6131 N NE2 . HIS B 1 365 ? -27.815 43.036 7.570 1.00 64.05 ? 338 HIS B NE2 1 ATOM 6132 N N . PRO B 1 366 ? -27.482 38.678 8.692 1.00 45.89 ? 339 PRO B N 1 ATOM 6133 C CA . PRO B 1 366 ? -27.018 37.695 7.719 1.00 49.17 ? 339 PRO B CA 1 ATOM 6134 C C . PRO B 1 366 ? -25.745 38.099 6.988 1.00 52.21 ? 339 PRO B C 1 ATOM 6135 O O . PRO B 1 366 ? -24.975 37.244 6.571 1.00 51.36 ? 339 PRO B O 1 ATOM 6136 C CB . PRO B 1 366 ? -28.196 37.562 6.742 1.00 50.35 ? 339 PRO B CB 1 ATOM 6137 C CG . PRO B 1 366 ? -29.088 38.705 7.006 1.00 47.51 ? 339 PRO B CG 1 ATOM 6138 C CD . PRO B 1 366 ? -28.846 39.150 8.406 1.00 48.66 ? 339 PRO B CD 1 ATOM 6139 N N . ARG B 1 367 ? -25.543 39.396 6.823 1.00 57.61 ? 340 ARG B N 1 ATOM 6140 C CA . ARG B 1 367 ? -24.311 39.913 6.232 1.00 63.14 ? 340 ARG B CA 1 ATOM 6141 C C . ARG B 1 367 ? -23.193 39.944 7.266 1.00 60.37 ? 340 ARG B C 1 ATOM 6142 O O . ARG B 1 367 ? -22.161 39.325 7.071 1.00 61.43 ? 340 ARG B O 1 ATOM 6143 C CB . ARG B 1 367 ? -24.530 41.323 5.648 1.00 61.46 ? 340 ARG B CB 1 ATOM 6144 N N . LYS B 1 368 ? -23.413 40.663 8.361 1.00 64.84 ? 341 LYS B N 1 ATOM 6145 C CA . LYS B 1 368 ? -22.354 40.935 9.345 1.00 67.71 ? 341 LYS B CA 1 ATOM 6146 C C . LYS B 1 368 ? -21.895 39.698 10.146 1.00 69.26 ? 341 LYS B C 1 ATOM 6147 O O . LYS B 1 368 ? -20.707 39.575 10.460 1.00 70.25 ? 341 LYS B O 1 ATOM 6148 C CB . LYS B 1 368 ? -22.783 42.051 10.300 1.00 65.73 ? 341 LYS B CB 1 ATOM 6149 N N . SER B 1 369 ? -22.812 38.777 10.453 1.00 64.74 ? 342 SER B N 1 ATOM 6150 C CA . SER B 1 369 ? -22.467 37.567 11.227 1.00 60.33 ? 342 SER B CA 1 ATOM 6151 C C . SER B 1 369 ? -21.744 36.525 10.359 1.00 59.00 ? 342 SER B C 1 ATOM 6152 O O . SER B 1 369 ? -22.297 35.475 10.013 1.00 54.61 ? 342 SER B O 1 ATOM 6153 C CB . SER B 1 369 ? -23.721 36.959 11.863 1.00 58.61 ? 342 SER B CB 1 ATOM 6154 O OG . SER B 1 369 ? -24.496 37.941 12.547 1.00 58.52 ? 342 SER B OG 1 ATOM 6155 N N . VAL B 1 370 ? -20.492 36.824 10.036 1.00 60.97 ? 343 VAL B N 1 ATOM 6156 C CA . VAL B 1 370 ? -19.679 35.991 9.153 1.00 62.48 ? 343 VAL B CA 1 ATOM 6157 C C . VAL B 1 370 ? -19.460 34.583 9.703 1.00 62.22 ? 343 VAL B C 1 ATOM 6158 O O . VAL B 1 370 ? -19.373 33.628 8.937 1.00 64.86 ? 343 VAL B O 1 ATOM 6159 C CB . VAL B 1 370 ? -18.289 36.643 8.908 1.00 64.85 ? 343 VAL B CB 1 ATOM 6160 N N . HIS B 1 371 ? -19.356 34.458 11.026 1.00 60.93 ? 344 HIS B N 1 ATOM 6161 C CA . HIS B 1 371 ? -19.016 33.176 11.656 1.00 57.96 ? 344 HIS B CA 1 ATOM 6162 C C . HIS B 1 371 ? -20.229 32.255 11.889 1.00 55.82 ? 344 HIS B C 1 ATOM 6163 O O . HIS B 1 371 ? -20.087 31.031 11.929 1.00 59.35 ? 344 HIS B O 1 ATOM 6164 C CB . HIS B 1 371 ? -18.284 33.437 12.967 1.00 58.31 ? 344 HIS B CB 1 ATOM 6165 C CG . HIS B 1 371 ? -16.995 34.182 12.792 1.00 61.94 ? 344 HIS B CG 1 ATOM 6166 N ND1 . HIS B 1 371 ? -15.904 33.643 12.136 1.00 60.62 ? 344 HIS B ND1 1 ATOM 6167 C CD2 . HIS B 1 371 ? -16.625 35.427 13.177 1.00 60.15 ? 344 HIS B CD2 1 ATOM 6168 C CE1 . HIS B 1 371 ? -14.917 34.520 12.133 1.00 57.41 ? 344 HIS B CE1 1 ATOM 6169 N NE2 . HIS B 1 371 ? -15.328 35.609 12.761 1.00 60.06 ? 344 HIS B NE2 1 ATOM 6170 N N . ASN B 1 372 ? -21.417 32.840 11.989 1.00 46.79 ? 345 ASN B N 1 ATOM 6171 C CA . ASN B 1 372 ? -22.628 32.089 12.246 1.00 40.04 ? 345 ASN B CA 1 ATOM 6172 C C . ASN B 1 372 ? -23.462 31.843 10.986 1.00 41.05 ? 345 ASN B C 1 ATOM 6173 O O . ASN B 1 372 ? -24.353 32.622 10.666 1.00 42.98 ? 345 ASN B O 1 ATOM 6174 C CB . ASN B 1 372 ? -23.446 32.848 13.283 1.00 39.31 ? 345 ASN B CB 1 ATOM 6175 C CG . ASN B 1 372 ? -24.628 32.059 13.805 1.00 37.57 ? 345 ASN B CG 1 ATOM 6176 O OD1 . ASN B 1 372 ? -25.001 31.019 13.257 1.00 37.12 ? 345 ASN B OD1 1 ATOM 6177 N ND2 . ASN B 1 372 ? -25.255 32.579 14.855 1.00 36.83 ? 345 ASN B ND2 1 ATOM 6178 N N . GLY B 1 373 ? -23.212 30.719 10.327 1.00 38.44 ? 346 GLY B N 1 ATOM 6179 C CA . GLY B 1 373 ? -23.973 30.291 9.178 1.00 39.25 ? 346 GLY B CA 1 ATOM 6180 C C . GLY B 1 373 ? -25.425 29.903 9.398 1.00 41.77 ? 346 GLY B C 1 ATOM 6181 O O . GLY B 1 373 ? -26.072 29.467 8.445 1.00 50.84 ? 346 GLY B O 1 ATOM 6182 N N . PHE B 1 374 ? -25.948 30.029 10.622 1.00 38.49 ? 347 PHE B N 1 ATOM 6183 C CA . PHE B 1 374 ? -27.372 29.842 10.882 1.00 37.29 ? 347 PHE B CA 1 ATOM 6184 C C . PHE B 1 374 ? -28.113 31.167 10.823 1.00 37.73 ? 347 PHE B C 1 ATOM 6185 O O . PHE B 1 374 ? -29.336 31.196 10.834 1.00 39.28 ? 347 PHE B O 1 ATOM 6186 C CB . PHE B 1 374 ? -27.623 29.217 12.263 1.00 35.09 ? 347 PHE B CB 1 ATOM 6187 C CG . PHE B 1 374 ? -27.073 27.842 12.398 1.00 32.65 ? 347 PHE B CG 1 ATOM 6188 C CD1 . PHE B 1 374 ? -27.688 26.776 11.775 1.00 30.21 ? 347 PHE B CD1 1 ATOM 6189 C CD2 . PHE B 1 374 ? -25.925 27.614 13.155 1.00 33.34 ? 347 PHE B CD2 1 ATOM 6190 C CE1 . PHE B 1 374 ? -27.174 25.491 11.895 1.00 33.12 ? 347 PHE B CE1 1 ATOM 6191 C CE2 . PHE B 1 374 ? -25.406 26.343 13.283 1.00 31.73 ? 347 PHE B CE2 1 ATOM 6192 C CZ . PHE B 1 374 ? -26.036 25.273 12.660 1.00 34.56 ? 347 PHE B CZ 1 ATOM 6193 N N . ALA B 1 375 ? -27.368 32.265 10.793 1.00 38.20 ? 348 ALA B N 1 ATOM 6194 C CA . ALA B 1 375 ? -27.981 33.584 10.787 1.00 39.03 ? 348 ALA B CA 1 ATOM 6195 C C . ALA B 1 375 ? -28.815 33.827 9.509 1.00 38.25 ? 348 ALA B C 1 ATOM 6196 O O . ALA B 1 375 ? -29.866 34.453 9.564 1.00 39.52 ? 348 ALA B O 1 ATOM 6197 C CB . ALA B 1 375 ? -26.911 34.651 10.937 1.00 41.57 ? 348 ALA B CB 1 ATOM 6198 N N . LYS B 1 376 ? -28.347 33.295 8.389 1.00 38.71 ? 349 LYS B N 1 ATOM 6199 C CA . LYS B 1 376 ? -29.053 33.372 7.131 1.00 42.18 ? 349 LYS B CA 1 ATOM 6200 C C . LYS B 1 376 ? -30.464 32.821 7.288 1.00 44.65 ? 349 LYS B C 1 ATOM 6201 O O . LYS B 1 376 ? -31.440 33.572 7.161 1.00 45.76 ? 349 LYS B O 1 ATOM 6202 C CB . LYS B 1 376 ? -28.292 32.588 6.058 1.00 41.83 ? 349 LYS B CB 1 ATOM 6203 N N . GLU B 1 377 ? -30.584 31.528 7.593 1.00 43.36 ? 350 GLU B N 1 ATOM 6204 C CA . GLU B 1 377 ? -31.911 30.912 7.710 1.00 43.79 ? 350 GLU B CA 1 ATOM 6205 C C . GLU B 1 377 ? -32.738 31.572 8.803 1.00 40.90 ? 350 GLU B C 1 ATOM 6206 O O . GLU B 1 377 ? -33.961 31.723 8.667 1.00 42.06 ? 350 GLU B O 1 ATOM 6207 C CB . GLU B 1 377 ? -31.837 29.400 7.934 1.00 45.53 ? 350 GLU B CB 1 ATOM 6208 C CG . GLU B 1 377 ? -33.211 28.739 7.931 1.00 50.25 ? 350 GLU B CG 1 ATOM 6209 C CD . GLU B 1 377 ? -33.181 27.247 8.208 1.00 55.57 ? 350 GLU B CD 1 ATOM 6210 O OE1 . GLU B 1 377 ? -32.080 26.721 8.498 1.00 60.26 ? 350 GLU B OE1 1 ATOM 6211 O OE2 . GLU B 1 377 ? -34.275 26.609 8.146 1.00 51.31 ? 350 GLU B OE2 1 ATOM 6212 N N . PHE B 1 378 ? -32.085 31.974 9.889 1.00 36.55 ? 351 PHE B N 1 ATOM 6213 C CA . PHE B 1 378 ? -32.783 32.702 10.938 1.00 36.20 ? 351 PHE B CA 1 ATOM 6214 C C . PHE B 1 378 ? -33.512 33.911 10.369 1.00 34.48 ? 351 PHE B C 1 ATOM 6215 O O . PHE B 1 378 ? -34.633 34.217 10.749 1.00 36.68 ? 351 PHE B O 1 ATOM 6216 C CB . PHE B 1 378 ? -31.807 33.182 12.022 1.00 34.75 ? 351 PHE B CB 1 ATOM 6217 C CG . PHE B 1 378 ? -32.386 34.246 12.917 1.00 34.48 ? 351 PHE B CG 1 ATOM 6218 C CD1 . PHE B 1 378 ? -33.268 33.915 13.918 1.00 35.91 ? 351 PHE B CD1 1 ATOM 6219 C CD2 . PHE B 1 378 ? -32.086 35.581 12.719 1.00 36.60 ? 351 PHE B CD2 1 ATOM 6220 C CE1 . PHE B 1 378 ? -33.831 34.885 14.726 1.00 37.03 ? 351 PHE B CE1 1 ATOM 6221 C CE2 . PHE B 1 378 ? -32.651 36.557 13.525 1.00 36.20 ? 351 PHE B CE2 1 ATOM 6222 C CZ . PHE B 1 378 ? -33.520 36.210 14.530 1.00 37.20 ? 351 PHE B CZ 1 ATOM 6223 N N . TRP B 1 379 ? -32.823 34.628 9.497 1.00 39.95 ? 352 TRP B N 1 ATOM 6224 C CA . TRP B 1 379 ? -33.340 35.872 8.932 1.00 43.39 ? 352 TRP B CA 1 ATOM 6225 C C . TRP B 1 379 ? -34.532 35.569 8.049 1.00 38.22 ? 352 TRP B C 1 ATOM 6226 O O . TRP B 1 379 ? -35.607 36.149 8.199 1.00 41.17 ? 352 TRP B O 1 ATOM 6227 C CB . TRP B 1 379 ? -32.232 36.573 8.125 1.00 45.87 ? 352 TRP B CB 1 ATOM 6228 C CG . TRP B 1 379 ? -32.459 38.038 7.991 1.00 51.43 ? 352 TRP B CG 1 ATOM 6229 C CD1 . TRP B 1 379 ? -32.917 38.689 6.896 1.00 51.18 ? 352 TRP B CD1 1 ATOM 6230 C CD2 . TRP B 1 379 ? -32.237 39.043 8.994 1.00 53.60 ? 352 TRP B CD2 1 ATOM 6231 N NE1 . TRP B 1 379 ? -33.000 40.034 7.146 1.00 53.69 ? 352 TRP B NE1 1 ATOM 6232 C CE2 . TRP B 1 379 ? -32.584 40.284 8.423 1.00 55.83 ? 352 TRP B CE2 1 ATOM 6233 C CE3 . TRP B 1 379 ? -31.772 39.014 10.310 1.00 54.70 ? 352 TRP B CE3 1 ATOM 6234 C CZ2 . TRP B 1 379 ? -32.492 41.491 9.125 1.00 55.00 ? 352 TRP B CZ2 1 ATOM 6235 C CZ3 . TRP B 1 379 ? -31.679 40.207 11.013 1.00 57.80 ? 352 TRP B CZ3 1 ATOM 6236 C CH2 . TRP B 1 379 ? -32.038 41.433 10.417 1.00 58.60 ? 352 TRP B CH2 1 ATOM 6237 N N . GLU B 1 380 ? -34.318 34.632 7.141 1.00 38.71 ? 353 GLU B N 1 ATOM 6238 C CA . GLU B 1 380 ? -35.347 34.164 6.214 1.00 41.49 ? 353 GLU B CA 1 ATOM 6239 C C . GLU B 1 380 ? -36.591 33.678 6.919 1.00 43.94 ? 353 GLU B C 1 ATOM 6240 O O . GLU B 1 380 ? -37.700 33.978 6.491 1.00 42.12 ? 353 GLU B O 1 ATOM 6241 C CB . GLU B 1 380 ? -34.785 33.059 5.338 1.00 40.68 ? 353 GLU B CB 1 ATOM 6242 C CG . GLU B 1 380 ? -33.702 33.570 4.399 1.00 44.86 ? 353 GLU B CG 1 ATOM 6243 C CD . GLU B 1 380 ? -33.200 32.507 3.447 1.00 48.00 ? 353 GLU B CD 1 ATOM 6244 O OE1 . GLU B 1 380 ? -33.394 31.302 3.732 1.00 54.45 ? 353 GLU B OE1 1 ATOM 6245 O OE2 . GLU B 1 380 ? -32.591 32.877 2.420 1.00 52.67 ? 353 GLU B OE2 1 ATOM 6246 N N . GLU B 1 381 ? -36.419 32.952 8.022 1.00 43.01 ? 354 GLU B N 1 ATOM 6247 C CA . GLU B 1 381 ? -37.562 32.461 8.765 1.00 43.16 ? 354 GLU B CA 1 ATOM 6248 C C . GLU B 1 381 ? -38.253 33.573 9.509 1.00 43.53 ? 354 GLU B C 1 ATOM 6249 O O . GLU B 1 381 ? -39.476 33.607 9.562 1.00 45.96 ? 354 GLU B O 1 ATOM 6250 C CB . GLU B 1 381 ? -37.145 31.365 9.739 1.00 44.15 ? 354 GLU B CB 1 ATOM 6251 C CG . GLU B 1 381 ? -36.861 30.071 9.037 1.00 46.27 ? 354 GLU B CG 1 ATOM 6252 C CD . GLU B 1 381 ? -38.131 29.529 8.445 1.00 47.90 ? 354 GLU B CD 1 ATOM 6253 O OE1 . GLU B 1 381 ? -38.147 29.388 7.227 1.00 52.43 ? 354 GLU B OE1 1 ATOM 6254 O OE2 . GLU B 1 381 ? -39.112 29.326 9.197 1.00 48.73 ? 354 GLU B OE2 1 ATOM 6255 N N . THR B 1 382 ? -37.484 34.489 10.086 1.00 43.11 ? 355 THR B N 1 ATOM 6256 C CA . THR B 1 382 ? -38.077 35.576 10.879 1.00 44.57 ? 355 THR B CA 1 ATOM 6257 C C . THR B 1 382 ? -38.937 36.498 9.984 1.00 44.68 ? 355 THR B C 1 ATOM 6258 O O . THR B 1 382 ? -40.054 36.878 10.351 1.00 45.44 ? 355 THR B O 1 ATOM 6259 C CB . THR B 1 382 ? -36.985 36.428 11.575 1.00 46.92 ? 355 THR B CB 1 ATOM 6260 O OG1 . THR B 1 382 ? -36.207 35.609 12.468 1.00 45.91 ? 355 THR B OG1 1 ATOM 6261 C CG2 . THR B 1 382 ? -37.596 37.575 12.351 1.00 46.74 ? 355 THR B CG2 1 ATOM 6262 N N . PHE B 1 383 ? -38.405 36.850 8.825 1.00 43.92 ? 356 PHE B N 1 ATOM 6263 C CA . PHE B 1 383 ? -39.029 37.858 7.964 1.00 51.53 ? 356 PHE B CA 1 ATOM 6264 C C . PHE B 1 383 ? -39.752 37.276 6.754 1.00 54.10 ? 356 PHE B C 1 ATOM 6265 O O . PHE B 1 383 ? -40.294 38.023 5.945 1.00 54.48 ? 356 PHE B O 1 ATOM 6266 C CB . PHE B 1 383 ? -37.967 38.859 7.520 1.00 49.53 ? 356 PHE B CB 1 ATOM 6267 C CG . PHE B 1 383 ? -37.335 39.581 8.671 1.00 50.21 ? 356 PHE B CG 1 ATOM 6268 C CD1 . PHE B 1 383 ? -38.104 40.399 9.497 1.00 49.79 ? 356 PHE B CD1 1 ATOM 6269 C CD2 . PHE B 1 383 ? -35.989 39.412 8.963 1.00 51.44 ? 356 PHE B CD2 1 ATOM 6270 C CE1 . PHE B 1 383 ? -37.532 41.052 10.578 1.00 50.16 ? 356 PHE B CE1 1 ATOM 6271 C CE2 . PHE B 1 383 ? -35.417 40.066 10.041 1.00 51.07 ? 356 PHE B CE2 1 ATOM 6272 C CZ . PHE B 1 383 ? -36.187 40.887 10.847 1.00 49.14 ? 356 PHE B CZ 1 ATOM 6273 N N . ASN B 1 384 ? -39.791 35.947 6.662 1.00 57.90 ? 357 ASN B N 1 ATOM 6274 C CA . ASN B 1 384 ? -40.540 35.248 5.622 1.00 58.45 ? 357 ASN B CA 1 ATOM 6275 C C . ASN B 1 384 ? -40.081 35.682 4.227 1.00 55.21 ? 357 ASN B C 1 ATOM 6276 O O . ASN B 1 384 ? -40.890 36.047 3.380 1.00 59.45 ? 357 ASN B O 1 ATOM 6277 C CB . ASN B 1 384 ? -42.037 35.509 5.830 1.00 59.09 ? 357 ASN B CB 1 ATOM 6278 C CG . ASN B 1 384 ? -42.914 34.409 5.284 1.00 62.56 ? 357 ASN B CG 1 ATOM 6279 O OD1 . ASN B 1 384 ? -44.002 34.184 5.807 1.00 67.70 ? 357 ASN B OD1 1 ATOM 6280 N ND2 . ASN B 1 384 ? -42.471 33.734 4.228 1.00 57.21 ? 357 ASN B ND2 1 ATOM 6281 N N . CYS B 1 385 ? -38.777 35.619 3.999 1.00 50.10 ? 358 CYS B N 1 ATOM 6282 C CA . CYS B 1 385 ? -38.182 36.126 2.787 1.00 49.19 ? 358 CYS B CA 1 ATOM 6283 C C . CYS B 1 385 ? -37.003 35.265 2.366 1.00 51.50 ? 358 CYS B C 1 ATOM 6284 O O . CYS B 1 385 ? -36.623 34.352 3.075 1.00 51.31 ? 358 CYS B O 1 ATOM 6285 C CB . CYS B 1 385 ? -37.754 37.588 2.987 1.00 56.00 ? 358 CYS B CB 1 ATOM 6286 S SG . CYS B 1 385 ? -36.574 37.918 4.330 1.00 59.81 ? 358 CYS B SG 1 ATOM 6287 N N . HIS B 1 386 ? -36.434 35.554 1.203 1.00 53.13 ? 359 HIS B N 1 ATOM 6288 C CA . HIS B 1 386 ? -35.323 34.790 0.654 1.00 55.46 ? 359 HIS B CA 1 ATOM 6289 C C . HIS B 1 386 ? -34.101 35.684 0.561 1.00 59.62 ? 359 HIS B C 1 ATOM 6290 O O . HIS B 1 386 ? -34.224 36.878 0.307 1.00 62.82 ? 359 HIS B O 1 ATOM 6291 C CB . HIS B 1 386 ? -35.696 34.243 -0.728 1.00 58.67 ? 359 HIS B CB 1 ATOM 6292 C CG . HIS B 1 386 ? -34.544 33.661 -1.484 1.00 61.65 ? 359 HIS B CG 1 ATOM 6293 N ND1 . HIS B 1 386 ? -34.038 32.407 -1.219 1.00 66.43 ? 359 HIS B ND1 1 ATOM 6294 C CD2 . HIS B 1 386 ? -33.809 34.155 -2.509 1.00 64.27 ? 359 HIS B CD2 1 ATOM 6295 C CE1 . HIS B 1 386 ? -33.038 32.153 -2.047 1.00 66.50 ? 359 HIS B CE1 1 ATOM 6296 N NE2 . HIS B 1 386 ? -32.877 33.199 -2.838 1.00 64.94 ? 359 HIS B NE2 1 ATOM 6297 N N . LEU B 1 387 ? -32.921 35.100 0.735 1.00 63.87 ? 360 LEU B N 1 ATOM 6298 C CA . LEU B 1 387 ? -31.667 35.859 0.713 1.00 68.83 ? 360 LEU B CA 1 ATOM 6299 C C . LEU B 1 387 ? -30.917 35.746 -0.610 1.00 68.21 ? 360 LEU B C 1 ATOM 6300 O O . LEU B 1 387 ? -30.699 34.647 -1.114 1.00 70.30 ? 360 LEU B O 1 ATOM 6301 C CB . LEU B 1 387 ? -30.743 35.378 1.835 1.00 74.03 ? 360 LEU B CB 1 ATOM 6302 C CG . LEU B 1 387 ? -30.087 36.417 2.716 1.00 77.58 ? 360 LEU B CG 1 ATOM 6303 C CD1 . LEU B 1 387 ? -31.084 37.467 3.167 1.00 76.26 ? 360 LEU B CD1 1 ATOM 6304 C CD2 . LEU B 1 387 ? -29.453 35.700 3.900 1.00 77.79 ? 360 LEU B CD2 1 ATOM 6305 N N . GLN B 1 388 ? -30.506 36.896 -1.143 1.00 74.07 ? 361 GLN B N 1 ATOM 6306 C CA . GLN B 1 388 ? -29.643 36.970 -2.326 1.00 74.18 ? 361 GLN B CA 1 ATOM 6307 C C . GLN B 1 388 ? -28.238 36.465 -2.017 1.00 72.64 ? 361 GLN B C 1 ATOM 6308 O O . GLN B 1 388 ? -27.828 35.419 -2.512 1.00 75.00 ? 361 GLN B O 1 ATOM 6309 C CB . GLN B 1 388 ? -29.565 38.418 -2.829 1.00 74.53 ? 361 GLN B CB 1 ATOM 6310 N N . PHE B 1 418 ? -44.287 33.048 -4.986 1.00 44.62 ? 391 PHE B N 1 ATOM 6311 C CA . PHE B 1 418 ? -43.064 33.845 -4.902 1.00 47.00 ? 391 PHE B CA 1 ATOM 6312 C C . PHE B 1 418 ? -42.669 34.162 -3.451 1.00 44.73 ? 391 PHE B C 1 ATOM 6313 O O . PHE B 1 418 ? -43.478 34.666 -2.669 1.00 45.74 ? 391 PHE B O 1 ATOM 6314 C CB . PHE B 1 418 ? -43.229 35.166 -5.688 1.00 47.13 ? 391 PHE B CB 1 ATOM 6315 C CG . PHE B 1 418 ? -42.002 36.018 -5.696 1.00 44.76 ? 391 PHE B CG 1 ATOM 6316 C CD1 . PHE B 1 418 ? -40.832 35.556 -6.286 1.00 48.96 ? 391 PHE B CD1 1 ATOM 6317 C CD2 . PHE B 1 418 ? -42.013 37.286 -5.137 1.00 46.78 ? 391 PHE B CD2 1 ATOM 6318 C CE1 . PHE B 1 418 ? -39.675 36.342 -6.314 1.00 50.30 ? 391 PHE B CE1 1 ATOM 6319 C CE2 . PHE B 1 418 ? -40.876 38.084 -5.165 1.00 50.21 ? 391 PHE B CE2 1 ATOM 6320 C CZ . PHE B 1 418 ? -39.699 37.613 -5.752 1.00 51.33 ? 391 PHE B CZ 1 ATOM 6321 N N . ARG B 1 419 ? -41.411 33.902 -3.116 1.00 44.82 ? 392 ARG B N 1 ATOM 6322 C CA . ARG B 1 419 ? -40.865 34.257 -1.822 1.00 48.71 ? 392 ARG B CA 1 ATOM 6323 C C . ARG B 1 419 ? -40.148 35.588 -1.989 1.00 44.27 ? 392 ARG B C 1 ATOM 6324 O O . ARG B 1 419 ? -39.134 35.671 -2.686 1.00 40.65 ? 392 ARG B O 1 ATOM 6325 C CB . ARG B 1 419 ? -39.890 33.183 -1.364 1.00 53.29 ? 392 ARG B CB 1 ATOM 6326 C CG . ARG B 1 419 ? -39.392 33.340 0.059 1.00 63.33 ? 392 ARG B CG 1 ATOM 6327 C CD . ARG B 1 419 ? -38.953 31.975 0.558 1.00 69.74 ? 392 ARG B CD 1 ATOM 6328 N NE . ARG B 1 419 ? -38.314 31.993 1.875 1.00 75.88 ? 392 ARG B NE 1 ATOM 6329 C CZ . ARG B 1 419 ? -38.959 32.059 3.039 1.00 73.71 ? 392 ARG B CZ 1 ATOM 6330 N NH1 . ARG B 1 419 ? -40.278 32.153 3.082 1.00 73.08 ? 392 ARG B NH1 1 ATOM 6331 N NH2 . ARG B 1 419 ? -38.278 32.053 4.176 1.00 72.52 ? 392 ARG B NH2 1 ATOM 6332 N N . PRO B 1 420 ? -40.666 36.636 -1.360 1.00 46.57 ? 393 PRO B N 1 ATOM 6333 C CA . PRO B 1 420 ? -40.041 37.954 -1.543 1.00 53.35 ? 393 PRO B CA 1 ATOM 6334 C C . PRO B 1 420 ? -38.573 37.956 -1.102 1.00 61.74 ? 393 PRO B C 1 ATOM 6335 O O . PRO B 1 420 ? -38.233 37.214 -0.171 1.00 66.58 ? 393 PRO B O 1 ATOM 6336 C CB . PRO B 1 420 ? -40.916 38.879 -0.693 1.00 51.99 ? 393 PRO B CB 1 ATOM 6337 C CG . PRO B 1 420 ? -41.665 37.982 0.249 1.00 51.34 ? 393 PRO B CG 1 ATOM 6338 C CD . PRO B 1 420 ? -41.782 36.651 -0.397 1.00 49.08 ? 393 PRO B CD 1 ATOM 6339 N N . LEU B 1 421 ? -37.703 38.700 -1.800 1.00 61.29 ? 394 LEU B N 1 ATOM 6340 C CA . LEU B 1 421 ? -36.295 38.835 -1.387 1.00 63.52 ? 394 LEU B CA 1 ATOM 6341 C C . LEU B 1 421 ? -36.193 39.687 -0.118 1.00 69.83 ? 394 LEU B C 1 ATOM 6342 O O . LEU B 1 421 ? -37.005 40.596 0.088 1.00 71.91 ? 394 LEU B O 1 ATOM 6343 C CB . LEU B 1 421 ? -35.436 39.455 -2.497 1.00 58.84 ? 394 LEU B CB 1 ATOM 6344 N N . CYS B 1 422 ? -35.214 39.370 0.737 1.00 70.31 ? 395 CYS B N 1 ATOM 6345 C CA . CYS B 1 422 ? -34.971 40.141 1.966 1.00 68.58 ? 395 CYS B CA 1 ATOM 6346 C C . CYS B 1 422 ? -34.174 41.383 1.614 1.00 64.38 ? 395 CYS B C 1 ATOM 6347 O O . CYS B 1 422 ? -33.240 41.319 0.812 1.00 57.02 ? 395 CYS B O 1 ATOM 6348 C CB . CYS B 1 422 ? -34.177 39.341 3.019 1.00 69.22 ? 395 CYS B CB 1 ATOM 6349 S SG . CYS B 1 422 ? -34.762 37.674 3.439 1.00 68.43 ? 395 CYS B SG 1 ATOM 6350 N N . THR B 1 423 ? -34.531 42.507 2.228 1.00 68.32 ? 396 THR B N 1 ATOM 6351 C CA . THR B 1 423 ? -33.816 43.762 1.988 1.00 69.50 ? 396 THR B CA 1 ATOM 6352 C C . THR B 1 423 ? -32.427 43.708 2.618 1.00 68.14 ? 396 THR B C 1 ATOM 6353 O O . THR B 1 423 ? -31.470 44.236 2.061 1.00 72.12 ? 396 THR B O 1 ATOM 6354 C CB . THR B 1 423 ? -34.596 44.997 2.511 1.00 69.56 ? 396 THR B CB 1 ATOM 6355 O OG1 . THR B 1 423 ? -34.715 44.953 3.938 1.00 62.27 ? 396 THR B OG1 1 ATOM 6356 C CG2 . THR B 1 423 ? -35.998 45.069 1.895 1.00 71.23 ? 396 THR B CG2 1 ATOM 6357 N N . GLY B 1 424 ? -32.319 43.033 3.759 1.00 68.52 ? 397 GLY B N 1 ATOM 6358 C CA . GLY B 1 424 ? -31.113 43.071 4.569 1.00 66.54 ? 397 GLY B CA 1 ATOM 6359 C C . GLY B 1 424 ? -31.140 44.216 5.566 1.00 68.98 ? 397 GLY B C 1 ATOM 6360 O O . GLY B 1 424 ? -30.182 44.417 6.295 1.00 73.60 ? 397 GLY B O 1 ATOM 6361 N N . ASP B 1 425 ? -32.239 44.966 5.610 1.00 68.89 ? 398 ASP B N 1 ATOM 6362 C CA . ASP B 1 425 ? -32.349 46.142 6.474 1.00 66.59 ? 398 ASP B CA 1 ATOM 6363 C C . ASP B 1 425 ? -33.528 46.020 7.416 1.00 62.23 ? 398 ASP B C 1 ATOM 6364 O O . ASP B 1 425 ? -33.851 46.967 8.128 1.00 61.37 ? 398 ASP B O 1 ATOM 6365 C CB . ASP B 1 425 ? -32.544 47.413 5.628 1.00 72.05 ? 398 ASP B CB 1 ATOM 6366 C CG . ASP B 1 425 ? -31.426 47.632 4.607 1.00 76.50 ? 398 ASP B CG 1 ATOM 6367 O OD1 . ASP B 1 425 ? -30.233 47.525 4.969 1.00 79.71 ? 398 ASP B OD1 1 ATOM 6368 O OD2 . ASP B 1 425 ? -31.750 47.929 3.437 1.00 78.09 ? 398 ASP B OD2 1 ATOM 6369 N N . GLU B 1 426 ? -34.185 44.867 7.433 1.00 58.36 ? 399 GLU B N 1 ATOM 6370 C CA . GLU B 1 426 ? -35.407 44.745 8.222 1.00 57.16 ? 399 GLU B CA 1 ATOM 6371 C C . GLU B 1 426 ? -35.067 44.657 9.723 1.00 56.04 ? 399 GLU B C 1 ATOM 6372 O O . GLU B 1 426 ? -33.895 44.595 10.111 1.00 52.31 ? 399 GLU B O 1 ATOM 6373 C CB . GLU B 1 426 ? -36.326 43.606 7.737 1.00 59.29 ? 399 GLU B CB 1 ATOM 6374 C CG . GLU B 1 426 ? -35.638 42.361 7.208 1.00 60.20 ? 399 GLU B CG 1 ATOM 6375 C CD . GLU B 1 426 ? -35.338 42.392 5.726 1.00 55.69 ? 399 GLU B CD 1 ATOM 6376 O OE1 . GLU B 1 426 ? -36.295 42.435 4.930 1.00 61.41 ? 399 GLU B OE1 1 ATOM 6377 O OE2 . GLU B 1 426 ? -34.142 42.339 5.349 1.00 54.88 ? 399 GLU B OE2 1 ATOM 6378 N N . ASN B 1 427 ? -36.091 44.733 10.559 1.00 51.58 ? 400 ASN B N 1 ATOM 6379 C CA . ASN B 1 427 ? -35.893 44.986 11.961 1.00 57.88 ? 400 ASN B CA 1 ATOM 6380 C C . ASN B 1 427 ? -36.342 43.845 12.869 1.00 57.41 ? 400 ASN B C 1 ATOM 6381 O O . ASN B 1 427 ? -37.541 43.550 12.959 1.00 53.06 ? 400 ASN B O 1 ATOM 6382 C CB . ASN B 1 427 ? -36.622 46.273 12.365 1.00 59.53 ? 400 ASN B CB 1 ATOM 6383 C CG . ASN B 1 427 ? -36.107 46.831 13.667 1.00 66.05 ? 400 ASN B CG 1 ATOM 6384 O OD1 . ASN B 1 427 ? -36.531 46.413 14.744 1.00 69.06 ? 400 ASN B OD1 1 ATOM 6385 N ND2 . ASN B 1 427 ? -35.156 47.761 13.577 1.00 68.49 ? 400 ASN B ND2 1 ATOM 6386 N N . ILE B 1 428 ? -35.374 43.254 13.579 1.00 55.37 ? 401 ILE B N 1 ATOM 6387 C CA . ILE B 1 428 ? -35.633 42.127 14.488 1.00 56.54 ? 401 ILE B CA 1 ATOM 6388 C C . ILE B 1 428 ? -36.786 42.419 15.445 1.00 54.25 ? 401 ILE B C 1 ATOM 6389 O O . ILE B 1 428 ? -37.550 41.514 15.782 1.00 52.98 ? 401 ILE B O 1 ATOM 6390 C CB . ILE B 1 428 ? -34.351 41.714 15.264 1.00 62.71 ? 401 ILE B CB 1 ATOM 6391 C CG1 . ILE B 1 428 ? -33.400 40.971 14.325 1.00 65.16 ? 401 ILE B CG1 1 ATOM 6392 C CG2 . ILE B 1 428 ? -34.652 40.804 16.452 1.00 63.28 ? 401 ILE B CG2 1 ATOM 6393 C CD1 . ILE B 1 428 ? -31.956 41.048 14.768 1.00 70.39 ? 401 ILE B CD1 1 ATOM 6394 N N . SER B 1 429 ? -36.934 43.678 15.858 1.00 53.19 ? 402 SER B N 1 ATOM 6395 C CA . SER B 1 429 ? -37.963 44.036 16.837 1.00 53.44 ? 402 SER B CA 1 ATOM 6396 C C . SER B 1 429 ? -39.399 44.119 16.284 1.00 52.74 ? 402 SER B C 1 ATOM 6397 O O . SER B 1 429 ? -40.346 44.226 17.056 1.00 53.41 ? 402 SER B O 1 ATOM 6398 C CB . SER B 1 429 ? -37.572 45.346 17.539 1.00 54.03 ? 402 SER B CB 1 ATOM 6399 N N . SER B 1 430 ? -39.576 44.035 14.967 1.00 54.53 ? 403 SER B N 1 ATOM 6400 C CA . SER B 1 430 ? -40.914 44.151 14.380 1.00 54.62 ? 403 SER B CA 1 ATOM 6401 C C . SER B 1 430 ? -41.713 42.842 14.359 1.00 62.01 ? 403 SER B C 1 ATOM 6402 O O . SER B 1 430 ? -42.941 42.865 14.177 1.00 58.88 ? 403 SER B O 1 ATOM 6403 C CB . SER B 1 430 ? -40.805 44.692 12.962 1.00 55.63 ? 403 SER B CB 1 ATOM 6404 O OG . SER B 1 430 ? -40.124 43.772 12.135 1.00 54.97 ? 403 SER B OG 1 ATOM 6405 N N . VAL B 1 431 ? -41.028 41.707 14.532 1.00 63.73 ? 404 VAL B N 1 ATOM 6406 C CA . VAL B 1 431 ? -41.667 40.386 14.437 1.00 60.37 ? 404 VAL B CA 1 ATOM 6407 C C . VAL B 1 431 ? -41.493 39.639 15.751 1.00 56.77 ? 404 VAL B C 1 ATOM 6408 O O . VAL B 1 431 ? -40.373 39.444 16.201 1.00 51.82 ? 404 VAL B O 1 ATOM 6409 C CB . VAL B 1 431 ? -41.050 39.527 13.306 1.00 62.32 ? 404 VAL B CB 1 ATOM 6410 C CG1 . VAL B 1 431 ? -41.900 38.292 13.048 1.00 61.32 ? 404 VAL B CG1 1 ATOM 6411 C CG2 . VAL B 1 431 ? -40.893 40.333 12.019 1.00 63.91 ? 404 VAL B CG2 1 ATOM 6412 N N . GLU B 1 432 ? -42.605 39.217 16.350 1.00 59.03 ? 405 GLU B N 1 ATOM 6413 C CA . GLU B 1 432 ? -42.579 38.458 17.601 1.00 58.39 ? 405 GLU B CA 1 ATOM 6414 C C . GLU B 1 432 ? -42.299 36.974 17.323 1.00 55.58 ? 405 GLU B C 1 ATOM 6415 O O . GLU B 1 432 ? -43.102 36.279 16.689 1.00 57.04 ? 405 GLU B O 1 ATOM 6416 C CB . GLU B 1 432 ? -43.905 38.613 18.371 1.00 56.11 ? 405 GLU B CB 1 ATOM 6417 N N . THR B 1 433 ? -41.134 36.518 17.771 1.00 49.97 ? 406 THR B N 1 ATOM 6418 C CA . THR B 1 433 ? -40.805 35.099 17.842 1.00 46.37 ? 406 THR B CA 1 ATOM 6419 C C . THR B 1 433 ? -40.189 34.859 19.219 1.00 48.26 ? 406 THR B C 1 ATOM 6420 O O . THR B 1 433 ? -39.894 35.808 19.942 1.00 45.38 ? 406 THR B O 1 ATOM 6421 C CB . THR B 1 433 ? -39.777 34.691 16.780 1.00 45.76 ? 406 THR B CB 1 ATOM 6422 O OG1 . THR B 1 433 ? -38.525 35.337 17.050 1.00 42.06 ? 406 THR B OG1 1 ATOM 6423 C CG2 . THR B 1 433 ? -40.265 35.048 15.339 1.00 45.86 ? 406 THR B CG2 1 ATOM 6424 N N . PRO B 1 434 ? -39.980 33.591 19.595 1.00 46.68 ? 407 PRO B N 1 ATOM 6425 C CA . PRO B 1 434 ? -39.265 33.340 20.864 1.00 43.81 ? 407 PRO B CA 1 ATOM 6426 C C . PRO B 1 434 ? -37.815 33.824 20.891 1.00 43.28 ? 407 PRO B C 1 ATOM 6427 O O . PRO B 1 434 ? -37.192 33.847 21.960 1.00 46.46 ? 407 PRO B O 1 ATOM 6428 C CB . PRO B 1 434 ? -39.322 31.820 20.995 1.00 45.90 ? 407 PRO B CB 1 ATOM 6429 C CG . PRO B 1 434 ? -40.588 31.447 20.275 1.00 46.95 ? 407 PRO B CG 1 ATOM 6430 C CD . PRO B 1 434 ? -40.689 32.394 19.109 1.00 43.85 ? 407 PRO B CD 1 ATOM 6431 N N . TYR B 1 435 ? -37.263 34.217 19.748 1.00 38.37 ? 408 TYR B N 1 ATOM 6432 C CA . TYR B 1 435 ? -35.878 34.658 19.725 1.00 40.07 ? 408 TYR B CA 1 ATOM 6433 C C . TYR B 1 435 ? -35.646 35.745 20.757 1.00 44.40 ? 408 TYR B C 1 ATOM 6434 O O . TYR B 1 435 ? -34.710 35.669 21.558 1.00 49.60 ? 408 TYR B O 1 ATOM 6435 C CB . TYR B 1 435 ? -35.505 35.173 18.348 1.00 36.40 ? 408 TYR B CB 1 ATOM 6436 C CG . TYR B 1 435 ? -34.091 35.651 18.227 1.00 38.11 ? 408 TYR B CG 1 ATOM 6437 C CD1 . TYR B 1 435 ? -33.035 34.798 18.497 1.00 38.65 ? 408 TYR B CD1 1 ATOM 6438 C CD2 . TYR B 1 435 ? -33.790 36.956 17.826 1.00 38.84 ? 408 TYR B CD2 1 ATOM 6439 C CE1 . TYR B 1 435 ? -31.730 35.216 18.373 1.00 37.93 ? 408 TYR B CE1 1 ATOM 6440 C CE2 . TYR B 1 435 ? -32.473 37.381 17.697 1.00 39.50 ? 408 TYR B CE2 1 ATOM 6441 C CZ . TYR B 1 435 ? -31.448 36.507 17.987 1.00 37.52 ? 408 TYR B CZ 1 ATOM 6442 O OH . TYR B 1 435 ? -30.123 36.852 17.854 1.00 34.00 ? 408 TYR B OH 1 ATOM 6443 N N . ILE B 1 436 ? -36.498 36.758 20.709 1.00 47.02 ? 409 ILE B N 1 ATOM 6444 C CA . ILE B 1 436 ? -36.381 37.914 21.571 1.00 51.04 ? 409 ILE B CA 1 ATOM 6445 C C . ILE B 1 436 ? -37.595 38.135 22.458 1.00 50.60 ? 409 ILE B C 1 ATOM 6446 O O . ILE B 1 436 ? -37.485 38.826 23.457 1.00 50.25 ? 409 ILE B O 1 ATOM 6447 C CB . ILE B 1 436 ? -36.047 39.178 20.744 1.00 56.12 ? 409 ILE B CB 1 ATOM 6448 C CG1 . ILE B 1 436 ? -34.880 39.896 21.384 1.00 58.59 ? 409 ILE B CG1 1 ATOM 6449 C CG2 . ILE B 1 436 ? -37.242 40.113 20.538 1.00 58.71 ? 409 ILE B CG2 1 ATOM 6450 C CD1 . ILE B 1 436 ? -33.571 39.199 21.121 1.00 57.75 ? 409 ILE B CD1 1 ATOM 6451 N N . ASP B 1 437 ? -38.734 37.543 22.130 1.00 49.09 ? 410 ASP B N 1 ATOM 6452 C CA . ASP B 1 437 ? -39.893 37.648 22.994 1.00 52.66 ? 410 ASP B CA 1 ATOM 6453 C C . ASP B 1 437 ? -39.779 36.659 24.151 1.00 52.74 ? 410 ASP B C 1 ATOM 6454 O O . ASP B 1 437 ? -40.406 35.605 24.138 1.00 54.54 ? 410 ASP B O 1 ATOM 6455 C CB . ASP B 1 437 ? -41.187 37.421 22.206 1.00 57.86 ? 410 ASP B CB 1 ATOM 6456 C CG . ASP B 1 437 ? -42.446 37.625 23.056 1.00 64.23 ? 410 ASP B CG 1 ATOM 6457 O OD1 . ASP B 1 437 ? -42.348 38.191 24.167 1.00 72.81 ? 410 ASP B OD1 1 ATOM 6458 O OD2 . ASP B 1 437 ? -43.544 37.204 22.618 1.00 70.22 ? 410 ASP B OD2 1 ATOM 6459 N N . TYR B 1 438 ? -38.985 37.015 25.161 1.00 50.79 ? 411 TYR B N 1 ATOM 6460 C CA . TYR B 1 438 ? -38.876 36.222 26.400 1.00 45.96 ? 411 TYR B CA 1 ATOM 6461 C C . TYR B 1 438 ? -38.777 37.179 27.564 1.00 45.46 ? 411 TYR B C 1 ATOM 6462 O O . TYR B 1 438 ? -38.263 38.278 27.425 1.00 45.25 ? 411 TYR B O 1 ATOM 6463 C CB . TYR B 1 438 ? -37.614 35.325 26.394 1.00 42.27 ? 411 TYR B CB 1 ATOM 6464 C CG . TYR B 1 438 ? -36.299 36.109 26.336 1.00 38.22 ? 411 TYR B CG 1 ATOM 6465 C CD1 . TYR B 1 438 ? -35.702 36.605 27.495 1.00 35.13 ? 411 TYR B CD1 1 ATOM 6466 C CD2 . TYR B 1 438 ? -35.684 36.382 25.125 1.00 36.37 ? 411 TYR B CD2 1 ATOM 6467 C CE1 . TYR B 1 438 ? -34.532 37.332 27.445 1.00 31.37 ? 411 TYR B CE1 1 ATOM 6468 C CE2 . TYR B 1 438 ? -34.506 37.103 25.072 1.00 36.89 ? 411 TYR B CE2 1 ATOM 6469 C CZ . TYR B 1 438 ? -33.944 37.580 26.251 1.00 34.21 ? 411 TYR B CZ 1 ATOM 6470 O OH . TYR B 1 438 ? -32.774 38.312 26.189 1.00 38.29 ? 411 TYR B OH 1 ATOM 6471 N N . THR B 1 439 ? -39.186 36.728 28.736 1.00 46.82 ? 412 THR B N 1 ATOM 6472 C CA . THR B 1 439 ? -38.935 37.522 29.920 1.00 51.98 ? 412 THR B CA 1 ATOM 6473 C C . THR B 1 439 ? -37.750 36.969 30.750 1.00 50.07 ? 412 THR B C 1 ATOM 6474 O O . THR B 1 439 ? -36.867 37.717 31.112 1.00 49.30 ? 412 THR B O 1 ATOM 6475 C CB . THR B 1 439 ? -40.211 37.794 30.750 1.00 55.22 ? 412 THR B CB 1 ATOM 6476 O OG1 . THR B 1 439 ? -39.830 38.320 32.024 1.00 63.32 ? 412 THR B OG1 1 ATOM 6477 C CG2 . THR B 1 439 ? -41.057 36.547 30.953 1.00 57.66 ? 412 THR B CG2 1 ATOM 6478 N N . HIS B 1 440 ? -37.689 35.665 30.997 1.00 47.80 ? 413 HIS B N 1 ATOM 6479 C CA . HIS B 1 440 ? -36.584 35.077 31.786 1.00 46.05 ? 413 HIS B CA 1 ATOM 6480 C C . HIS B 1 440 ? -35.687 34.167 30.951 1.00 43.47 ? 413 HIS B C 1 ATOM 6481 O O . HIS B 1 440 ? -36.166 33.419 30.107 1.00 46.41 ? 413 HIS B O 1 ATOM 6482 C CB . HIS B 1 440 ? -37.127 34.260 32.947 1.00 47.30 ? 413 HIS B CB 1 ATOM 6483 C CG . HIS B 1 440 ? -38.057 35.012 33.844 1.00 49.94 ? 413 HIS B CG 1 ATOM 6484 N ND1 . HIS B 1 440 ? -37.618 35.785 34.897 1.00 51.68 ? 413 HIS B ND1 1 ATOM 6485 C CD2 . HIS B 1 440 ? -39.407 35.099 33.852 1.00 53.37 ? 413 HIS B CD2 1 ATOM 6486 C CE1 . HIS B 1 440 ? -38.655 36.321 35.512 1.00 51.84 ? 413 HIS B CE1 1 ATOM 6487 N NE2 . HIS B 1 440 ? -39.753 35.922 34.897 1.00 55.13 ? 413 HIS B NE2 1 ATOM 6488 N N . LEU B 1 441 ? -34.380 34.241 31.192 1.00 39.40 ? 414 LEU B N 1 ATOM 6489 C CA . LEU B 1 441 ? -33.419 33.310 30.629 1.00 36.14 ? 414 LEU B CA 1 ATOM 6490 C C . LEU B 1 441 ? -33.254 32.146 31.598 1.00 38.98 ? 414 LEU B C 1 ATOM 6491 O O . LEU B 1 441 ? -32.820 32.349 32.731 1.00 38.30 ? 414 LEU B O 1 ATOM 6492 C CB . LEU B 1 441 ? -32.060 33.959 30.441 1.00 34.53 ? 414 LEU B CB 1 ATOM 6493 C CG . LEU B 1 441 ? -32.085 35.161 29.511 1.00 35.00 ? 414 LEU B CG 1 ATOM 6494 C CD1 . LEU B 1 441 ? -30.817 35.975 29.659 1.00 34.25 ? 414 LEU B CD1 1 ATOM 6495 C CD2 . LEU B 1 441 ? -32.266 34.696 28.085 1.00 35.54 ? 414 LEU B CD2 1 ATOM 6496 N N . ARG B 1 442 ? -33.566 30.931 31.135 1.00 34.81 ? 415 ARG B N 1 ATOM 6497 C CA . ARG B 1 442 ? -33.459 29.747 31.959 1.00 32.88 ? 415 ARG B CA 1 ATOM 6498 C C . ARG B 1 442 ? -32.495 28.747 31.319 1.00 31.57 ? 415 ARG B C 1 ATOM 6499 O O . ARG B 1 442 ? -31.336 28.661 31.752 1.00 29.15 ? 415 ARG B O 1 ATOM 6500 C CB . ARG B 1 442 ? -34.838 29.164 32.208 1.00 34.19 ? 415 ARG B CB 1 ATOM 6501 C CG . ARG B 1 442 ? -35.813 30.189 32.777 1.00 36.26 ? 415 ARG B CG 1 ATOM 6502 C CD . ARG B 1 442 ? -37.035 29.512 33.363 1.00 39.00 ? 415 ARG B CD 1 ATOM 6503 N NE . ARG B 1 442 ? -38.212 30.375 33.490 1.00 42.57 ? 415 ARG B NE 1 ATOM 6504 C CZ . ARG B 1 442 ? -38.661 30.915 34.631 1.00 46.64 ? 415 ARG B CZ 1 ATOM 6505 N NH1 . ARG B 1 442 ? -38.044 30.719 35.797 1.00 48.46 ? 415 ARG B NH1 1 ATOM 6506 N NH2 . ARG B 1 442 ? -39.749 31.668 34.609 1.00 47.48 ? 415 ARG B NH2 1 ATOM 6507 N N . ILE B 1 443 ? -32.930 28.044 30.264 1.00 26.70 ? 416 ILE B N 1 ATOM 6508 C CA . ILE B 1 443 ? -32.025 27.166 29.534 1.00 26.64 ? 416 ILE B CA 1 ATOM 6509 C C . ILE B 1 443 ? -30.874 27.984 28.950 1.00 27.65 ? 416 ILE B C 1 ATOM 6510 O O . ILE B 1 443 ? -29.747 27.528 28.913 1.00 28.49 ? 416 ILE B O 1 ATOM 6511 C CB . ILE B 1 443 ? -32.723 26.374 28.412 1.00 25.30 ? 416 ILE B CB 1 ATOM 6512 C CG1 . ILE B 1 443 ? -33.884 25.522 28.950 1.00 25.90 ? 416 ILE B CG1 1 ATOM 6513 C CG2 . ILE B 1 443 ? -31.737 25.507 27.658 1.00 23.47 ? 416 ILE B CG2 1 ATOM 6514 C CD1 . ILE B 1 443 ? -33.470 24.449 29.900 1.00 27.29 ? 416 ILE B CD1 1 ATOM 6515 N N . SER B 1 444 ? -31.155 29.191 28.486 1.00 28.21 ? 417 SER B N 1 ATOM 6516 C CA . SER B 1 444 ? -30.101 30.062 27.961 1.00 27.85 ? 417 SER B CA 1 ATOM 6517 C C . SER B 1 444 ? -29.020 30.300 29.004 1.00 27.00 ? 417 SER B C 1 ATOM 6518 O O . SER B 1 444 ? -27.833 30.370 28.692 1.00 26.97 ? 417 SER B O 1 ATOM 6519 C CB . SER B 1 444 ? -30.687 31.404 27.517 1.00 29.00 ? 417 SER B CB 1 ATOM 6520 O OG . SER B 1 444 ? -31.817 31.249 26.665 1.00 29.96 ? 417 SER B OG 1 ATOM 6521 N N . TYR B 1 445 ? -29.430 30.445 30.249 1.00 29.27 ? 418 TYR B N 1 ATOM 6522 C CA . TYR B 1 445 ? -28.466 30.622 31.327 1.00 32.28 ? 418 TYR B CA 1 ATOM 6523 C C . TYR B 1 445 ? -27.620 29.358 31.531 1.00 30.45 ? 418 TYR B C 1 ATOM 6524 O O . TYR B 1 445 ? -26.412 29.451 31.694 1.00 31.87 ? 418 TYR B O 1 ATOM 6525 C CB . TYR B 1 445 ? -29.154 31.035 32.621 1.00 31.62 ? 418 TYR B CB 1 ATOM 6526 C CG . TYR B 1 445 ? -28.156 31.464 33.660 1.00 34.40 ? 418 TYR B CG 1 ATOM 6527 C CD1 . TYR B 1 445 ? -27.376 32.594 33.459 1.00 34.37 ? 418 TYR B CD1 1 ATOM 6528 C CD2 . TYR B 1 445 ? -27.979 30.748 34.840 1.00 35.92 ? 418 TYR B CD2 1 ATOM 6529 C CE1 . TYR B 1 445 ? -26.450 33.012 34.404 1.00 36.33 ? 418 TYR B CE1 1 ATOM 6530 C CE2 . TYR B 1 445 ? -27.037 31.154 35.790 1.00 38.75 ? 418 TYR B CE2 1 ATOM 6531 C CZ . TYR B 1 445 ? -26.282 32.293 35.565 1.00 37.25 ? 418 TYR B CZ 1 ATOM 6532 O OH . TYR B 1 445 ? -25.339 32.708 36.494 1.00 43.13 ? 418 TYR B OH 1 ATOM 6533 N N . ASN B 1 446 ? -28.252 28.184 31.467 1.00 29.94 ? 419 ASN B N 1 ATOM 6534 C CA . ASN B 1 446 ? -27.533 26.915 31.535 1.00 27.19 ? 419 ASN B CA 1 ATOM 6535 C C . ASN B 1 446 ? -26.493 26.774 30.440 1.00 28.14 ? 419 ASN B C 1 ATOM 6536 O O . ASN B 1 446 ? -25.387 26.211 30.653 1.00 26.44 ? 419 ASN B O 1 ATOM 6537 C CB . ASN B 1 446 ? -28.482 25.744 31.411 1.00 28.48 ? 419 ASN B CB 1 ATOM 6538 C CG . ASN B 1 446 ? -29.419 25.625 32.575 1.00 27.63 ? 419 ASN B CG 1 ATOM 6539 O OD1 . ASN B 1 446 ? -29.349 26.379 33.527 1.00 29.02 ? 419 ASN B OD1 1 ATOM 6540 N ND2 . ASN B 1 446 ? -30.334 24.688 32.478 1.00 31.24 ? 419 ASN B ND2 1 ATOM 6541 N N . VAL B 1 447 ? -26.810 27.290 29.257 1.00 26.99 ? 420 VAL B N 1 ATOM 6542 C CA . VAL B 1 447 ? -25.822 27.255 28.172 1.00 26.93 ? 420 VAL B CA 1 ATOM 6543 C C . VAL B 1 447 ? -24.590 28.090 28.531 1.00 27.54 ? 420 VAL B C 1 ATOM 6544 O O . VAL B 1 447 ? -23.465 27.668 28.351 1.00 26.20 ? 420 VAL B O 1 ATOM 6545 C CB . VAL B 1 447 ? -26.411 27.786 26.856 1.00 26.39 ? 420 VAL B CB 1 ATOM 6546 C CG1 . VAL B 1 447 ? -25.356 27.792 25.760 1.00 24.83 ? 420 VAL B CG1 1 ATOM 6547 C CG2 . VAL B 1 447 ? -27.606 26.936 26.435 1.00 27.16 ? 420 VAL B CG2 1 ATOM 6548 N N . TYR B 1 448 ? -24.864 29.318 28.962 1.00 32.51 ? 421 TYR B N 1 ATOM 6549 C CA . TYR B 1 448 ? -23.885 30.299 29.406 1.00 32.10 ? 421 TYR B CA 1 ATOM 6550 C C . TYR B 1 448 ? -22.984 29.713 30.505 1.00 31.49 ? 421 TYR B C 1 ATOM 6551 O O . TYR B 1 448 ? -21.757 29.788 30.415 1.00 30.25 ? 421 TYR B O 1 ATOM 6552 C CB . TYR B 1 448 ? -24.653 31.502 29.942 1.00 35.60 ? 421 TYR B CB 1 ATOM 6553 C CG . TYR B 1 448 ? -23.833 32.673 30.402 1.00 37.84 ? 421 TYR B CG 1 ATOM 6554 C CD1 . TYR B 1 448 ? -23.210 33.511 29.479 1.00 39.00 ? 421 TYR B CD1 1 ATOM 6555 C CD2 . TYR B 1 448 ? -23.745 33.002 31.765 1.00 39.31 ? 421 TYR B CD2 1 ATOM 6556 C CE1 . TYR B 1 448 ? -22.478 34.616 29.897 1.00 42.28 ? 421 TYR B CE1 1 ATOM 6557 C CE2 . TYR B 1 448 ? -23.021 34.113 32.189 1.00 41.55 ? 421 TYR B CE2 1 ATOM 6558 C CZ . TYR B 1 448 ? -22.399 34.918 31.245 1.00 40.51 ? 421 TYR B CZ 1 ATOM 6559 O OH . TYR B 1 448 ? -21.685 36.003 31.637 1.00 41.83 ? 421 TYR B OH 1 ATOM 6560 N N . LEU B 1 449 ? -23.598 29.092 31.504 1.00 31.78 ? 422 LEU B N 1 ATOM 6561 C CA . LEU B 1 449 ? -22.830 28.392 32.545 1.00 32.74 ? 422 LEU B CA 1 ATOM 6562 C C . LEU B 1 449 ? -22.048 27.200 32.053 1.00 30.93 ? 422 LEU B C 1 ATOM 6563 O O . LEU B 1 449 ? -20.989 26.898 32.603 1.00 30.70 ? 422 LEU B O 1 ATOM 6564 C CB . LEU B 1 449 ? -23.721 27.915 33.685 1.00 34.30 ? 422 LEU B CB 1 ATOM 6565 C CG . LEU B 1 449 ? -24.251 28.947 34.660 1.00 38.76 ? 422 LEU B CG 1 ATOM 6566 C CD1 . LEU B 1 449 ? -25.061 28.217 35.721 1.00 40.06 ? 422 LEU B CD1 1 ATOM 6567 C CD2 . LEU B 1 449 ? -23.121 29.749 35.301 1.00 39.46 ? 422 LEU B CD2 1 ATOM 6568 N N . ALA B 1 450 ? -22.560 26.498 31.051 1.00 28.88 ? 423 ALA B N 1 ATOM 6569 C CA . ALA B 1 450 ? -21.835 25.361 30.528 1.00 27.77 ? 423 ALA B CA 1 ATOM 6570 C C . ALA B 1 450 ? -20.537 25.837 29.914 1.00 28.78 ? 423 ALA B C 1 ATOM 6571 O O . ALA B 1 450 ? -19.461 25.210 30.092 1.00 25.74 ? 423 ALA B O 1 ATOM 6572 C CB . ALA B 1 450 ? -22.655 24.591 29.510 1.00 28.56 ? 423 ALA B CB 1 ATOM 6573 N N . VAL B 1 451 ? -20.612 26.933 29.172 1.00 28.14 ? 424 VAL B N 1 ATOM 6574 C CA . VAL B 1 451 ? -19.399 27.433 28.514 1.00 28.39 ? 424 VAL B CA 1 ATOM 6575 C C . VAL B 1 451 ? -18.388 27.941 29.566 1.00 28.28 ? 424 VAL B C 1 ATOM 6576 O O . VAL B 1 451 ? -17.194 27.671 29.481 1.00 29.80 ? 424 VAL B O 1 ATOM 6577 C CB . VAL B 1 451 ? -19.742 28.559 27.525 1.00 30.56 ? 424 VAL B CB 1 ATOM 6578 C CG1 . VAL B 1 451 ? -18.483 29.244 26.994 1.00 27.75 ? 424 VAL B CG1 1 ATOM 6579 C CG2 . VAL B 1 451 ? -20.585 28.003 26.365 1.00 31.42 ? 424 VAL B CG2 1 ATOM 6580 N N . TYR B 1 452 ? -18.893 28.677 30.541 1.00 27.96 ? 425 TYR B N 1 ATOM 6581 C CA . TYR B 1 452 ? -18.070 29.223 31.599 1.00 31.22 ? 425 TYR B CA 1 ATOM 6582 C C . TYR B 1 452 ? -17.462 28.120 32.490 1.00 31.57 ? 425 TYR B C 1 ATOM 6583 O O . TYR B 1 452 ? -16.341 28.263 32.965 1.00 34.48 ? 425 TYR B O 1 ATOM 6584 C CB . TYR B 1 452 ? -18.851 30.269 32.410 1.00 31.39 ? 425 TYR B CB 1 ATOM 6585 C CG . TYR B 1 452 ? -18.591 31.678 31.931 1.00 34.66 ? 425 TYR B CG 1 ATOM 6586 C CD1 . TYR B 1 452 ? -17.496 32.422 32.408 1.00 35.51 ? 425 TYR B CD1 1 ATOM 6587 C CD2 . TYR B 1 452 ? -19.425 32.277 31.010 1.00 36.47 ? 425 TYR B CD2 1 ATOM 6588 C CE1 . TYR B 1 452 ? -17.249 33.708 31.966 1.00 35.16 ? 425 TYR B CE1 1 ATOM 6589 C CE2 . TYR B 1 452 ? -19.182 33.562 30.555 1.00 37.13 ? 425 TYR B CE2 1 ATOM 6590 C CZ . TYR B 1 452 ? -18.090 34.269 31.028 1.00 39.88 ? 425 TYR B CZ 1 ATOM 6591 O OH . TYR B 1 452 ? -17.869 35.543 30.562 1.00 38.66 ? 425 TYR B OH 1 ATOM 6592 N N . SER B 1 453 ? -18.182 27.009 32.676 1.00 31.48 ? 426 SER B N 1 ATOM 6593 C CA . SER B 1 453 ? -17.629 25.868 33.382 1.00 28.63 ? 426 SER B CA 1 ATOM 6594 C C . SER B 1 453 ? -16.412 25.378 32.619 1.00 29.78 ? 426 SER B C 1 ATOM 6595 O O . SER B 1 453 ? -15.358 25.107 33.208 1.00 30.41 ? 426 SER B O 1 ATOM 6596 C CB . SER B 1 453 ? -18.661 24.752 33.546 1.00 29.08 ? 426 SER B CB 1 ATOM 6597 O OG . SER B 1 453 ? -19.736 25.158 34.381 1.00 31.03 ? 426 SER B OG 1 ATOM 6598 N N . ILE B 1 454 ? -16.532 25.242 31.307 1.00 27.57 ? 427 ILE B N 1 ATOM 6599 C CA . ILE B 1 454 ? -15.395 24.761 30.533 1.00 28.44 ? 427 ILE B CA 1 ATOM 6600 C C . ILE B 1 454 ? -14.233 25.779 30.620 1.00 30.30 ? 427 ILE B C 1 ATOM 6601 O O . ILE B 1 454 ? -13.068 25.405 30.781 1.00 31.67 ? 427 ILE B O 1 ATOM 6602 C CB . ILE B 1 454 ? -15.789 24.490 29.088 1.00 27.61 ? 427 ILE B CB 1 ATOM 6603 C CG1 . ILE B 1 454 ? -16.772 23.312 29.033 1.00 28.28 ? 427 ILE B CG1 1 ATOM 6604 C CG2 . ILE B 1 454 ? -14.571 24.194 28.235 1.00 27.45 ? 427 ILE B CG2 1 ATOM 6605 C CD1 . ILE B 1 454 ? -17.603 23.263 27.774 1.00 29.17 ? 427 ILE B CD1 1 ATOM 6606 N N . ALA B 1 455 ? -14.559 27.057 30.504 1.00 30.12 ? 428 ALA B N 1 ATOM 6607 C CA . ALA B 1 455 ? -13.560 28.112 30.494 1.00 30.61 ? 428 ALA B CA 1 ATOM 6608 C C . ALA B 1 455 ? -12.798 28.188 31.843 1.00 31.68 ? 428 ALA B C 1 ATOM 6609 O O . ALA B 1 455 ? -11.576 28.305 31.857 1.00 29.98 ? 428 ALA B O 1 ATOM 6610 C CB . ALA B 1 455 ? -14.214 29.440 30.206 1.00 29.80 ? 428 ALA B CB 1 ATOM 6611 N N . HIS B 1 456 ? -13.541 28.105 32.944 1.00 30.96 ? 429 HIS B N 1 ATOM 6612 C CA . HIS B 1 456 ? -12.944 28.070 34.268 1.00 32.85 ? 429 HIS B CA 1 ATOM 6613 C C . HIS B 1 456 ? -12.101 26.856 34.520 1.00 31.67 ? 429 HIS B C 1 ATOM 6614 O O . HIS B 1 456 ? -11.109 26.955 35.234 1.00 30.93 ? 429 HIS B O 1 ATOM 6615 C CB . HIS B 1 456 ? -13.997 28.209 35.352 1.00 34.23 ? 429 HIS B CB 1 ATOM 6616 C CG . HIS B 1 456 ? -14.481 29.609 35.517 1.00 39.67 ? 429 HIS B CG 1 ATOM 6617 N ND1 . HIS B 1 456 ? -13.648 30.634 35.905 1.00 43.06 ? 429 HIS B ND1 1 ATOM 6618 C CD2 . HIS B 1 456 ? -15.699 30.168 35.322 1.00 43.90 ? 429 HIS B CD2 1 ATOM 6619 C CE1 . HIS B 1 456 ? -14.339 31.756 35.976 1.00 44.32 ? 429 HIS B CE1 1 ATOM 6620 N NE2 . HIS B 1 456 ? -15.583 31.503 35.613 1.00 44.45 ? 429 HIS B NE2 1 ATOM 6621 N N . ALA B 1 457 ? -12.474 25.709 33.955 1.00 30.76 ? 430 ALA B N 1 ATOM 6622 C CA . ALA B 1 457 ? -11.663 24.511 34.092 1.00 30.95 ? 430 ALA B CA 1 ATOM 6623 C C . ALA B 1 457 ? -10.340 24.721 33.369 1.00 34.27 ? 430 ALA B C 1 ATOM 6624 O O . ALA B 1 457 ? -9.274 24.310 33.846 1.00 32.38 ? 430 ALA B O 1 ATOM 6625 C CB . ALA B 1 457 ? -12.369 23.288 33.539 1.00 28.81 ? 430 ALA B CB 1 ATOM 6626 N N . LEU B 1 458 ? -10.421 25.352 32.202 1.00 33.82 ? 431 LEU B N 1 ATOM 6627 C CA . LEU B 1 458 ? -9.231 25.727 31.448 1.00 34.05 ? 431 LEU B CA 1 ATOM 6628 C C . LEU B 1 458 ? -8.393 26.771 32.187 1.00 33.84 ? 431 LEU B C 1 ATOM 6629 O O . LEU B 1 458 ? -7.180 26.717 32.136 1.00 32.09 ? 431 LEU B O 1 ATOM 6630 C CB . LEU B 1 458 ? -9.613 26.271 30.071 1.00 33.78 ? 431 LEU B CB 1 ATOM 6631 C CG . LEU B 1 458 ? -10.201 25.254 29.090 1.00 31.36 ? 431 LEU B CG 1 ATOM 6632 C CD1 . LEU B 1 458 ? -10.828 26.000 27.930 1.00 33.17 ? 431 LEU B CD1 1 ATOM 6633 C CD2 . LEU B 1 458 ? -9.159 24.284 28.588 1.00 32.08 ? 431 LEU B CD2 1 ATOM 6634 N N . GLN B 1 459 ? -9.044 27.717 32.845 1.00 33.24 ? 432 GLN B N 1 ATOM 6635 C CA . GLN B 1 459 ? -8.338 28.717 33.606 1.00 38.48 ? 432 GLN B CA 1 ATOM 6636 C C . GLN B 1 459 ? -7.564 28.057 34.761 1.00 42.37 ? 432 GLN B C 1 ATOM 6637 O O . GLN B 1 459 ? -6.436 28.461 35.042 1.00 38.53 ? 432 GLN B O 1 ATOM 6638 C CB . GLN B 1 459 ? -9.299 29.784 34.131 1.00 40.44 ? 432 GLN B CB 1 ATOM 6639 C CG . GLN B 1 459 ? -8.674 30.910 34.959 1.00 44.39 ? 432 GLN B CG 1 ATOM 6640 C CD . GLN B 1 459 ? -7.805 31.875 34.158 1.00 51.48 ? 432 GLN B CD 1 ATOM 6641 O OE1 . GLN B 1 459 ? -7.707 31.793 32.925 1.00 53.75 ? 432 GLN B OE1 1 ATOM 6642 N NE2 . GLN B 1 459 ? -7.157 32.805 34.868 1.00 50.93 ? 432 GLN B NE2 1 ATOM 6643 N N . ASP B 1 460 ? -8.161 27.034 35.389 1.00 40.47 ? 433 ASP B N 1 ATOM 6644 C CA . ASP B 1 460 ? -7.503 26.279 36.463 1.00 39.13 ? 433 ASP B CA 1 ATOM 6645 C C . ASP B 1 460 ? -6.255 25.569 35.923 1.00 41.90 ? 433 ASP B C 1 ATOM 6646 O O . ASP B 1 460 ? -5.273 25.397 36.653 1.00 37.56 ? 433 ASP B O 1 ATOM 6647 C CB . ASP B 1 460 ? -8.449 25.266 37.112 1.00 38.19 ? 433 ASP B CB 1 ATOM 6648 C CG . ASP B 1 460 ? -9.539 25.921 37.982 1.00 37.83 ? 433 ASP B CG 1 ATOM 6649 O OD1 . ASP B 1 460 ? -9.482 27.125 38.263 1.00 39.36 ? 433 ASP B OD1 1 ATOM 6650 O OD2 . ASP B 1 460 ? -10.461 25.216 38.413 1.00 42.07 ? 433 ASP B OD2 1 ATOM 6651 N N . ILE B 1 461 ? -6.281 25.177 34.654 1.00 39.46 ? 434 ILE B N 1 ATOM 6652 C CA . ILE B 1 461 ? -5.087 24.620 34.017 1.00 41.66 ? 434 ILE B CA 1 ATOM 6653 C C . ILE B 1 461 ? -4.048 25.721 33.777 1.00 45.11 ? 434 ILE B C 1 ATOM 6654 O O . ILE B 1 461 ? -2.882 25.539 34.095 1.00 44.17 ? 434 ILE B O 1 ATOM 6655 C CB . ILE B 1 461 ? -5.396 23.900 32.695 1.00 39.56 ? 434 ILE B CB 1 ATOM 6656 C CG1 . ILE B 1 461 ? -6.183 22.613 32.976 1.00 38.15 ? 434 ILE B CG1 1 ATOM 6657 C CG2 . ILE B 1 461 ? -4.106 23.563 31.965 1.00 41.02 ? 434 ILE B CG2 1 ATOM 6658 C CD1 . ILE B 1 461 ? -6.734 21.944 31.737 1.00 39.70 ? 434 ILE B CD1 1 ATOM 6659 N N . TYR B 1 462 ? -4.487 26.867 33.268 1.00 43.79 ? 435 TYR B N 1 ATOM 6660 C CA . TYR B 1 462 ? -3.598 27.993 33.024 1.00 47.80 ? 435 TYR B CA 1 ATOM 6661 C C . TYR B 1 462 ? -2.823 28.425 34.274 1.00 46.39 ? 435 TYR B C 1 ATOM 6662 O O . TYR B 1 462 ? -1.624 28.654 34.204 1.00 45.90 ? 435 TYR B O 1 ATOM 6663 C CB . TYR B 1 462 ? -4.384 29.200 32.542 1.00 48.66 ? 435 TYR B CB 1 ATOM 6664 C CG . TYR B 1 462 ? -3.504 30.372 32.187 1.00 55.52 ? 435 TYR B CG 1 ATOM 6665 C CD1 . TYR B 1 462 ? -2.648 30.315 31.082 1.00 62.10 ? 435 TYR B CD1 1 ATOM 6666 C CD2 . TYR B 1 462 ? -3.515 31.540 32.955 1.00 55.67 ? 435 TYR B CD2 1 ATOM 6667 C CE1 . TYR B 1 462 ? -1.833 31.386 30.754 1.00 62.93 ? 435 TYR B CE1 1 ATOM 6668 C CE2 . TYR B 1 462 ? -2.699 32.610 32.634 1.00 58.96 ? 435 TYR B CE2 1 ATOM 6669 C CZ . TYR B 1 462 ? -1.864 32.524 31.533 1.00 60.92 ? 435 TYR B CZ 1 ATOM 6670 O OH . TYR B 1 462 ? -1.063 33.585 31.191 1.00 70.98 ? 435 TYR B OH 1 ATOM 6671 N N . THR B 1 463 ? -3.525 28.530 35.395 1.00 42.32 ? 436 THR B N 1 ATOM 6672 C CA . THR B 1 463 ? -2.965 29.034 36.633 1.00 43.23 ? 436 THR B CA 1 ATOM 6673 C C . THR B 1 463 ? -2.350 27.950 37.521 1.00 44.06 ? 436 THR B C 1 ATOM 6674 O O . THR B 1 463 ? -1.918 28.251 38.623 1.00 51.80 ? 436 THR B O 1 ATOM 6675 C CB . THR B 1 463 ? -4.044 29.742 37.473 1.00 40.16 ? 436 THR B CB 1 ATOM 6676 O OG1 . THR B 1 463 ? -5.092 28.809 37.802 1.00 40.03 ? 436 THR B OG1 1 ATOM 6677 C CG2 . THR B 1 463 ? -4.608 30.909 36.712 1.00 40.40 ? 436 THR B CG2 1 ATOM 6678 N N . CYS B 1 464 ? -2.308 26.706 37.056 1.00 42.99 ? 437 CYS B N 1 ATOM 6679 C CA . CYS B 1 464 ? -1.824 25.611 37.863 1.00 46.02 ? 437 CYS B CA 1 ATOM 6680 C C . CYS B 1 464 ? -0.326 25.804 38.181 1.00 48.84 ? 437 CYS B C 1 ATOM 6681 O O . CYS B 1 464 ? 0.478 26.065 37.286 1.00 47.14 ? 437 CYS B O 1 ATOM 6682 C CB . CYS B 1 464 ? -2.017 24.276 37.129 1.00 45.96 ? 437 CYS B CB 1 ATOM 6683 S SG . CYS B 1 464 ? -1.521 22.812 38.058 1.00 53.29 ? 437 CYS B SG 1 ATOM 6684 N N . LEU B 1 465 ? 0.034 25.632 39.448 1.00 52.87 ? 438 LEU B N 1 ATOM 6685 C CA . LEU B 1 465 ? 1.443 25.702 39.881 1.00 55.37 ? 438 LEU B CA 1 ATOM 6686 C C . LEU B 1 465 ? 1.965 24.308 40.227 1.00 48.04 ? 438 LEU B C 1 ATOM 6687 O O . LEU B 1 465 ? 1.314 23.568 40.968 1.00 46.01 ? 438 LEU B O 1 ATOM 6688 C CB . LEU B 1 465 ? 1.577 26.652 41.069 1.00 59.30 ? 438 LEU B CB 1 ATOM 6689 C CG . LEU B 1 465 ? 1.190 28.108 40.740 1.00 63.84 ? 438 LEU B CG 1 ATOM 6690 C CD1 . LEU B 1 465 ? 1.135 28.987 41.991 1.00 62.17 ? 438 LEU B CD1 1 ATOM 6691 C CD2 . LEU B 1 465 ? 2.133 28.703 39.694 1.00 62.65 ? 438 LEU B CD2 1 ATOM 6692 N N . PRO B 1 466 ? 3.122 23.935 39.663 1.00 47.89 ? 439 PRO B N 1 ATOM 6693 C CA . PRO B 1 466 ? 3.739 22.622 39.873 1.00 49.11 ? 439 PRO B CA 1 ATOM 6694 C C . PRO B 1 466 ? 3.700 22.169 41.330 1.00 46.72 ? 439 PRO B C 1 ATOM 6695 O O . PRO B 1 466 ? 3.980 22.968 42.237 1.00 45.17 ? 439 PRO B O 1 ATOM 6696 C CB . PRO B 1 466 ? 5.188 22.850 39.444 1.00 51.19 ? 439 PRO B CB 1 ATOM 6697 C CG . PRO B 1 466 ? 5.114 23.916 38.409 1.00 51.86 ? 439 PRO B CG 1 ATOM 6698 C CD . PRO B 1 466 ? 3.926 24.775 38.753 1.00 52.80 ? 439 PRO B CD 1 ATOM 6699 N N . GLY B 1 467 ? 3.354 20.905 41.546 1.00 42.99 ? 440 GLY B N 1 ATOM 6700 C CA . GLY B 1 467 ? 3.125 20.383 42.884 1.00 45.49 ? 440 GLY B CA 1 ATOM 6701 C C . GLY B 1 467 ? 1.702 20.585 43.384 1.00 48.83 ? 440 GLY B C 1 ATOM 6702 O O . GLY B 1 467 ? 1.208 19.794 44.181 1.00 49.90 ? 440 GLY B O 1 ATOM 6703 N N . ARG B 1 468 ? 1.045 21.651 42.924 1.00 54.47 ? 441 ARG B N 1 ATOM 6704 C CA . ARG B 1 468 ? -0.328 21.955 43.309 1.00 57.19 ? 441 ARG B CA 1 ATOM 6705 C C . ARG B 1 468 ? -1.372 21.498 42.260 1.00 54.62 ? 441 ARG B C 1 ATOM 6706 O O . ARG B 1 468 ? -2.548 21.816 42.392 1.00 51.78 ? 441 ARG B O 1 ATOM 6707 C CB . ARG B 1 468 ? -0.461 23.464 43.565 1.00 60.35 ? 441 ARG B CB 1 ATOM 6708 N N . GLY B 1 469 ? -0.935 20.749 41.248 1.00 48.68 ? 442 GLY B N 1 ATOM 6709 C CA . GLY B 1 469 ? -1.825 20.244 40.203 1.00 48.68 ? 442 GLY B CA 1 ATOM 6710 C C . GLY B 1 469 ? -2.599 18.967 40.545 1.00 44.50 ? 442 GLY B C 1 ATOM 6711 O O . GLY B 1 469 ? -2.404 18.372 41.601 1.00 43.41 ? 442 GLY B O 1 ATOM 6712 N N . LEU B 1 470 ? -3.491 18.552 39.645 1.00 41.24 ? 443 LEU B N 1 ATOM 6713 C CA . LEU B 1 470 ? -4.422 17.424 39.902 1.00 37.84 ? 443 LEU B CA 1 ATOM 6714 C C . LEU B 1 470 ? -3.916 16.106 39.364 1.00 36.16 ? 443 LEU B C 1 ATOM 6715 O O . LEU B 1 470 ? -4.451 15.039 39.667 1.00 37.97 ? 443 LEU B O 1 ATOM 6716 C CB . LEU B 1 470 ? -5.796 17.712 39.260 1.00 38.64 ? 443 LEU B CB 1 ATOM 6717 C CG . LEU B 1 470 ? -6.629 18.830 39.883 1.00 37.72 ? 443 LEU B CG 1 ATOM 6718 C CD1 . LEU B 1 470 ? -7.864 19.103 39.029 1.00 35.06 ? 443 LEU B CD1 1 ATOM 6719 C CD2 . LEU B 1 470 ? -7.036 18.492 41.305 1.00 38.90 ? 443 LEU B CD2 1 ATOM 6720 N N . PHE B 1 471 ? -2.891 16.160 38.530 1.00 37.16 ? 444 PHE B N 1 ATOM 6721 C CA . PHE B 1 471 ? -2.428 14.957 37.843 1.00 38.58 ? 444 PHE B CA 1 ATOM 6722 C C . PHE B 1 471 ? -1.294 14.297 38.648 1.00 40.54 ? 444 PHE B C 1 ATOM 6723 O O . PHE B 1 471 ? -1.087 14.647 39.806 1.00 41.85 ? 444 PHE B O 1 ATOM 6724 C CB . PHE B 1 471 ? -2.064 15.355 36.412 1.00 37.85 ? 444 PHE B CB 1 ATOM 6725 C CG . PHE B 1 471 ? -3.208 16.011 35.701 1.00 35.39 ? 444 PHE B CG 1 ATOM 6726 C CD1 . PHE B 1 471 ? -4.238 15.248 35.181 1.00 35.99 ? 444 PHE B CD1 1 ATOM 6727 C CD2 . PHE B 1 471 ? -3.309 17.391 35.640 1.00 39.66 ? 444 PHE B CD2 1 ATOM 6728 C CE1 . PHE B 1 471 ? -5.329 15.841 34.568 1.00 34.35 ? 444 PHE B CE1 1 ATOM 6729 C CE2 . PHE B 1 471 ? -4.401 17.995 35.022 1.00 39.85 ? 444 PHE B CE2 1 ATOM 6730 C CZ . PHE B 1 471 ? -5.419 17.211 34.494 1.00 35.49 ? 444 PHE B CZ 1 ATOM 6731 N N . THR B 1 472 ? -0.607 13.326 38.071 1.00 43.77 ? 445 THR B N 1 ATOM 6732 C CA . THR B 1 472 ? 0.408 12.566 38.801 1.00 49.00 ? 445 THR B CA 1 ATOM 6733 C C . THR B 1 472 ? 1.456 13.446 39.486 1.00 46.63 ? 445 THR B C 1 ATOM 6734 O O . THR B 1 472 ? 1.991 14.361 38.862 1.00 46.12 ? 445 THR B O 1 ATOM 6735 C CB . THR B 1 472 ? 1.161 11.646 37.836 1.00 51.10 ? 445 THR B CB 1 ATOM 6736 O OG1 . THR B 1 472 ? 0.215 10.926 37.036 1.00 52.51 ? 445 THR B OG1 1 ATOM 6737 C CG2 . THR B 1 472 ? 2.044 10.652 38.594 1.00 51.48 ? 445 THR B CG2 1 ATOM 6738 N N . ASN B 1 473 ? 1.744 13.162 40.757 1.00 48.12 ? 446 ASN B N 1 ATOM 6739 C CA . ASN B 1 473 ? 2.794 13.878 41.513 1.00 51.00 ? 446 ASN B CA 1 ATOM 6740 C C . ASN B 1 473 ? 2.547 15.386 41.588 1.00 50.23 ? 446 ASN B C 1 ATOM 6741 O O . ASN B 1 473 ? 3.486 16.190 41.518 1.00 48.09 ? 446 ASN B O 1 ATOM 6742 C CB . ASN B 1 473 ? 4.193 13.605 40.915 1.00 51.77 ? 446 ASN B CB 1 ATOM 6743 C CG . ASN B 1 473 ? 4.618 12.156 41.058 1.00 54.95 ? 446 ASN B CG 1 ATOM 6744 O OD1 . ASN B 1 473 ? 4.175 11.453 41.963 1.00 62.87 ? 446 ASN B OD1 1 ATOM 6745 N ND2 . ASN B 1 473 ? 5.485 11.705 40.165 1.00 59.83 ? 446 ASN B ND2 1 ATOM 6746 N N . GLY B 1 474 ? 1.274 15.761 41.704 1.00 46.30 ? 447 GLY B N 1 ATOM 6747 C CA . GLY B 1 474 ? 0.885 17.160 41.690 1.00 40.02 ? 447 GLY B CA 1 ATOM 6748 C C . GLY B 1 474 ? 1.295 17.875 40.418 1.00 38.28 ? 447 GLY B C 1 ATOM 6749 O O . GLY B 1 474 ? 1.407 19.096 40.416 1.00 38.51 ? 447 GLY B O 1 ATOM 6750 N N . SER B 1 475 ? 1.490 17.142 39.322 1.00 37.34 ? 448 SER B N 1 ATOM 6751 C CA . SER B 1 475 ? 1.845 17.770 38.065 1.00 39.45 ? 448 SER B CA 1 ATOM 6752 C C . SER B 1 475 ? 0.656 18.526 37.463 1.00 43.51 ? 448 SER B C 1 ATOM 6753 O O . SER B 1 475 ? -0.500 18.316 37.843 1.00 37.64 ? 448 SER B O 1 ATOM 6754 C CB . SER B 1 475 ? 2.371 16.754 37.062 1.00 40.50 ? 448 SER B CB 1 ATOM 6755 O OG . SER B 1 475 ? 1.396 15.767 36.792 1.00 43.25 ? 448 SER B OG 1 ATOM 6756 N N . CYS B 1 476 ? 0.980 19.415 36.529 1.00 45.84 ? 449 CYS B N 1 ATOM 6757 C CA . CYS B 1 476 ? 0.005 20.263 35.873 1.00 49.82 ? 449 CYS B CA 1 ATOM 6758 C C . CYS B 1 476 ? -0.098 19.834 34.432 1.00 48.87 ? 449 CYS B C 1 ATOM 6759 O O . CYS B 1 476 ? 0.825 19.246 33.896 1.00 50.69 ? 449 CYS B O 1 ATOM 6760 C CB . CYS B 1 476 ? 0.450 21.730 35.922 1.00 50.95 ? 449 CYS B CB 1 ATOM 6761 S SG . CYS B 1 476 ? 0.505 22.474 37.555 1.00 51.82 ? 449 CYS B SG 1 ATOM 6762 N N . ALA B 1 477 ? -1.231 20.127 33.811 1.00 48.86 ? 450 ALA B N 1 ATOM 6763 C CA . ALA B 1 477 ? -1.381 19.938 32.376 1.00 47.62 ? 450 ALA B CA 1 ATOM 6764 C C . ALA B 1 477 ? -0.822 21.173 31.690 1.00 47.40 ? 450 ALA B C 1 ATOM 6765 O O . ALA B 1 477 ? -0.797 22.245 32.269 1.00 45.32 ? 450 ALA B O 1 ATOM 6766 C CB . ALA B 1 477 ? -2.841 19.761 32.024 1.00 49.07 ? 450 ALA B CB 1 ATOM 6767 N N . ASP B 1 478 ? -0.360 21.012 30.462 1.00 48.88 ? 451 ASP B N 1 ATOM 6768 C CA . ASP B 1 478 ? 0.162 22.119 29.681 1.00 48.77 ? 451 ASP B CA 1 ATOM 6769 C C . ASP B 1 478 ? -0.953 22.707 28.831 1.00 47.10 ? 451 ASP B C 1 ATOM 6770 O O . ASP B 1 478 ? -1.442 22.048 27.930 1.00 49.07 ? 451 ASP B O 1 ATOM 6771 C CB . ASP B 1 478 ? 1.305 21.629 28.777 1.00 52.89 ? 451 ASP B CB 1 ATOM 6772 C CG . ASP B 1 478 ? 1.791 22.705 27.800 1.00 55.71 ? 451 ASP B CG 1 ATOM 6773 O OD1 . ASP B 1 478 ? 1.398 23.885 27.935 1.00 51.59 ? 451 ASP B OD1 1 ATOM 6774 O OD2 . ASP B 1 478 ? 2.562 22.359 26.888 1.00 63.96 ? 451 ASP B OD2 1 ATOM 6775 N N . ILE B 1 479 ? -1.306 23.959 29.081 1.00 47.01 ? 452 ILE B N 1 ATOM 6776 C CA . ILE B 1 479 ? -2.416 24.596 28.392 1.00 52.77 ? 452 ILE B CA 1 ATOM 6777 C C . ILE B 1 479 ? -2.162 24.848 26.898 1.00 59.97 ? 452 ILE B C 1 ATOM 6778 O O . ILE B 1 479 ? -3.109 25.058 26.142 1.00 60.58 ? 452 ILE B O 1 ATOM 6779 C CB . ILE B 1 479 ? -2.860 25.895 29.104 1.00 54.41 ? 452 ILE B CB 1 ATOM 6780 C CG1 . ILE B 1 479 ? -4.229 26.329 28.576 1.00 56.84 ? 452 ILE B CG1 1 ATOM 6781 C CG2 . ILE B 1 479 ? -1.819 27.006 28.965 1.00 53.95 ? 452 ILE B CG2 1 ATOM 6782 C CD1 . ILE B 1 479 ? -5.026 27.151 29.552 1.00 54.62 ? 452 ILE B CD1 1 ATOM 6783 N N . LYS B 1 480 ? -0.893 24.816 26.479 1.00 61.77 ? 453 LYS B N 1 ATOM 6784 C CA . LYS B 1 480 ? -0.541 24.894 25.063 1.00 60.17 ? 453 LYS B CA 1 ATOM 6785 C C . LYS B 1 480 ? -0.815 23.581 24.339 1.00 57.86 ? 453 LYS B C 1 ATOM 6786 O O . LYS B 1 480 ? -0.990 23.579 23.131 1.00 61.90 ? 453 LYS B O 1 ATOM 6787 C CB . LYS B 1 480 ? 0.948 25.241 24.888 1.00 64.01 ? 453 LYS B CB 1 ATOM 6788 C CG . LYS B 1 480 ? 1.428 26.524 25.556 1.00 66.26 ? 453 LYS B CG 1 ATOM 6789 C CD . LYS B 1 480 ? 0.454 27.657 25.311 1.00 72.98 ? 453 LYS B CD 1 ATOM 6790 C CE . LYS B 1 480 ? 1.034 29.003 25.686 1.00 78.73 ? 453 LYS B CE 1 ATOM 6791 N NZ . LYS B 1 480 ? -0.008 30.047 25.466 1.00 84.30 ? 453 LYS B NZ 1 ATOM 6792 N N . LYS B 1 481 ? -0.808 22.469 25.076 1.00 53.91 ? 454 LYS B N 1 ATOM 6793 C CA . LYS B 1 481 ? -1.079 21.132 24.534 1.00 50.33 ? 454 LYS B CA 1 ATOM 6794 C C . LYS B 1 481 ? -2.144 20.397 25.380 1.00 47.56 ? 454 LYS B C 1 ATOM 6795 O O . LYS B 1 481 ? -1.973 19.228 25.732 1.00 48.48 ? 454 LYS B O 1 ATOM 6796 C CB . LYS B 1 481 ? 0.205 20.292 24.481 1.00 50.02 ? 454 LYS B CB 1 ATOM 6797 N N . VAL B 1 482 ? -3.251 21.075 25.681 1.00 45.79 ? 455 VAL B N 1 ATOM 6798 C CA . VAL B 1 482 ? -4.302 20.476 26.528 1.00 43.28 ? 455 VAL B CA 1 ATOM 6799 C C . VAL B 1 482 ? -4.955 19.275 25.856 1.00 39.84 ? 455 VAL B C 1 ATOM 6800 O O . VAL B 1 482 ? -5.267 19.323 24.680 1.00 41.00 ? 455 VAL B O 1 ATOM 6801 C CB . VAL B 1 482 ? -5.502 21.398 26.850 1.00 47.69 ? 455 VAL B CB 1 ATOM 6802 C CG1 . VAL B 1 482 ? -5.863 21.255 28.319 1.00 49.92 ? 455 VAL B CG1 1 ATOM 6803 C CG2 . VAL B 1 482 ? -5.279 22.854 26.501 1.00 52.19 ? 455 VAL B CG2 1 ATOM 6804 N N . GLU B 1 483 ? -5.191 18.221 26.615 1.00 38.45 ? 456 GLU B N 1 ATOM 6805 C CA . GLU B 1 483 ? -5.970 17.084 26.147 1.00 40.02 ? 456 GLU B CA 1 ATOM 6806 C C . GLU B 1 483 ? -7.338 17.047 26.845 1.00 38.66 ? 456 GLU B C 1 ATOM 6807 O O . GLU B 1 483 ? -7.476 17.467 27.993 1.00 35.00 ? 456 GLU B O 1 ATOM 6808 C CB . GLU B 1 483 ? -5.195 15.793 26.358 1.00 43.82 ? 456 GLU B CB 1 ATOM 6809 C CG . GLU B 1 483 ? -3.956 15.761 25.459 1.00 52.39 ? 456 GLU B CG 1 ATOM 6810 C CD . GLU B 1 483 ? -3.056 14.564 25.684 1.00 60.48 ? 456 GLU B CD 1 ATOM 6811 O OE1 . GLU B 1 483 ? -3.246 13.806 26.663 1.00 61.13 ? 456 GLU B OE1 1 ATOM 6812 O OE2 . GLU B 1 483 ? -2.140 14.380 24.857 1.00 72.14 ? 456 GLU B OE2 1 ATOM 6813 N N . ALA B 1 484 ? -8.341 16.591 26.105 1.00 34.17 ? 457 ALA B N 1 ATOM 6814 C CA . ALA B 1 484 ? -9.738 16.625 26.541 1.00 32.22 ? 457 ALA B CA 1 ATOM 6815 C C . ALA B 1 484 ? -9.924 15.976 27.907 1.00 29.24 ? 457 ALA B C 1 ATOM 6816 O O . ALA B 1 484 ? -10.576 16.545 28.778 1.00 27.33 ? 457 ALA B O 1 ATOM 6817 C CB . ALA B 1 484 ? -10.604 15.925 25.504 1.00 32.74 ? 457 ALA B CB 1 ATOM 6818 N N . TRP B 1 485 ? -9.307 14.825 28.105 1.00 28.00 ? 458 TRP B N 1 ATOM 6819 C CA . TRP B 1 485 ? -9.402 14.134 29.377 1.00 32.18 ? 458 TRP B CA 1 ATOM 6820 C C . TRP B 1 485 ? -8.913 14.961 30.579 1.00 32.43 ? 458 TRP B C 1 ATOM 6821 O O . TRP B 1 485 ? -9.366 14.735 31.722 1.00 28.42 ? 458 TRP B O 1 ATOM 6822 C CB . TRP B 1 485 ? -8.683 12.787 29.324 1.00 35.75 ? 458 TRP B CB 1 ATOM 6823 C CG . TRP B 1 485 ? -7.183 12.869 29.224 1.00 38.21 ? 458 TRP B CG 1 ATOM 6824 C CD1 . TRP B 1 485 ? -6.426 12.934 28.076 1.00 37.67 ? 458 TRP B CD1 1 ATOM 6825 C CD2 . TRP B 1 485 ? -6.253 12.851 30.315 1.00 37.85 ? 458 TRP B CD2 1 ATOM 6826 N NE1 . TRP B 1 485 ? -5.080 12.988 28.396 1.00 38.01 ? 458 TRP B NE1 1 ATOM 6827 C CE2 . TRP B 1 485 ? -4.943 12.929 29.756 1.00 38.21 ? 458 TRP B CE2 1 ATOM 6828 C CE3 . TRP B 1 485 ? -6.393 12.793 31.707 1.00 38.04 ? 458 TRP B CE3 1 ATOM 6829 C CZ2 . TRP B 1 485 ? -3.786 12.951 30.546 1.00 37.91 ? 458 TRP B CZ2 1 ATOM 6830 C CZ3 . TRP B 1 485 ? -5.236 12.825 32.500 1.00 39.12 ? 458 TRP B CZ3 1 ATOM 6831 C CH2 . TRP B 1 485 ? -3.951 12.904 31.909 1.00 39.27 ? 458 TRP B CH2 1 ATOM 6832 N N . GLN B 1 486 ? -8.034 15.940 30.319 1.00 31.24 ? 459 GLN B N 1 ATOM 6833 C CA . GLN B 1 486 ? -7.492 16.791 31.385 1.00 33.09 ? 459 GLN B CA 1 ATOM 6834 C C . GLN B 1 486 ? -8.508 17.827 31.717 1.00 30.23 ? 459 GLN B C 1 ATOM 6835 O O . GLN B 1 486 ? -8.641 18.223 32.868 1.00 28.80 ? 459 GLN B O 1 ATOM 6836 C CB . GLN B 1 486 ? -6.168 17.461 30.973 1.00 32.39 ? 459 GLN B CB 1 ATOM 6837 C CG . GLN B 1 486 ? -5.052 16.453 30.804 1.00 34.07 ? 459 GLN B CG 1 ATOM 6838 C CD . GLN B 1 486 ? -3.833 17.006 30.079 1.00 37.80 ? 459 GLN B CD 1 ATOM 6839 O OE1 . GLN B 1 486 ? -3.933 17.856 29.180 1.00 39.65 ? 459 GLN B OE1 1 ATOM 6840 N NE2 . GLN B 1 486 ? -2.671 16.522 30.474 1.00 38.04 ? 459 GLN B NE2 1 ATOM 6841 N N . VAL B 1 487 ? -9.212 18.282 30.693 1.00 28.51 ? 460 VAL B N 1 ATOM 6842 C CA . VAL B 1 487 ? -10.296 19.225 30.903 1.00 29.08 ? 460 VAL B CA 1 ATOM 6843 C C . VAL B 1 487 ? -11.404 18.534 31.724 1.00 27.28 ? 460 VAL B C 1 ATOM 6844 O O . VAL B 1 487 ? -11.949 19.136 32.628 1.00 28.45 ? 460 VAL B O 1 ATOM 6845 C CB . VAL B 1 487 ? -10.821 19.802 29.576 1.00 30.65 ? 460 VAL B CB 1 ATOM 6846 C CG1 . VAL B 1 487 ? -11.882 20.866 29.837 1.00 30.99 ? 460 VAL B CG1 1 ATOM 6847 C CG2 . VAL B 1 487 ? -9.685 20.447 28.779 1.00 32.80 ? 460 VAL B CG2 1 ATOM 6848 N N . LEU B 1 488 ? -11.694 17.273 31.414 1.00 27.99 ? 461 LEU B N 1 ATOM 6849 C CA . LEU B 1 488 ? -12.696 16.488 32.139 1.00 26.90 ? 461 LEU B CA 1 ATOM 6850 C C . LEU B 1 488 ? -12.286 16.446 33.624 1.00 28.75 ? 461 LEU B C 1 ATOM 6851 O O . LEU B 1 488 ? -13.097 16.690 34.533 1.00 25.21 ? 461 LEU B O 1 ATOM 6852 C CB . LEU B 1 488 ? -12.776 15.078 31.552 1.00 26.56 ? 461 LEU B CB 1 ATOM 6853 C CG . LEU B 1 488 ? -13.995 14.144 31.654 1.00 30.54 ? 461 LEU B CG 1 ATOM 6854 C CD1 . LEU B 1 488 ? -13.659 12.677 31.757 1.00 29.66 ? 461 LEU B CD1 1 ATOM 6855 C CD2 . LEU B 1 488 ? -15.007 14.546 32.711 1.00 30.39 ? 461 LEU B CD2 1 ATOM 6856 N N . LYS B 1 489 ? -11.010 16.159 33.860 1.00 28.57 ? 462 LYS B N 1 ATOM 6857 C CA . LYS B 1 489 ? -10.495 16.094 35.221 1.00 28.81 ? 462 LYS B CA 1 ATOM 6858 C C . LYS B 1 489 ? -10.736 17.386 35.946 1.00 29.46 ? 462 LYS B C 1 ATOM 6859 O O . LYS B 1 489 ? -11.242 17.408 37.062 1.00 30.33 ? 462 LYS B O 1 ATOM 6860 C CB . LYS B 1 489 ? -9.008 15.746 35.194 1.00 32.84 ? 462 LYS B CB 1 ATOM 6861 C CG . LYS B 1 489 ? -8.320 15.745 36.556 1.00 34.99 ? 462 LYS B CG 1 ATOM 6862 C CD . LYS B 1 489 ? -8.961 14.780 37.528 1.00 34.20 ? 462 LYS B CD 1 ATOM 6863 C CE . LYS B 1 489 ? -8.095 14.672 38.777 1.00 36.39 ? 462 LYS B CE 1 ATOM 6864 N NZ . LYS B 1 489 ? -8.554 13.588 39.658 1.00 36.77 ? 462 LYS B NZ 1 ATOM 6865 N N . HIS B 1 490 ? -10.393 18.487 35.306 1.00 29.36 ? 463 HIS B N 1 ATOM 6866 C CA . HIS B 1 490 ? -10.603 19.763 35.909 1.00 30.14 ? 463 HIS B CA 1 ATOM 6867 C C . HIS B 1 490 ? -12.069 20.143 36.088 1.00 31.98 ? 463 HIS B C 1 ATOM 6868 O O . HIS B 1 490 ? -12.401 20.828 37.059 1.00 28.39 ? 463 HIS B O 1 ATOM 6869 C CB . HIS B 1 490 ? -9.852 20.837 35.136 1.00 33.63 ? 463 HIS B CB 1 ATOM 6870 C CG . HIS B 1 490 ? -8.433 20.972 35.582 1.00 34.76 ? 463 HIS B CG 1 ATOM 6871 N ND1 . HIS B 1 490 ? -8.066 21.808 36.606 1.00 33.99 ? 463 HIS B ND1 1 ATOM 6872 C CD2 . HIS B 1 490 ? -7.310 20.317 35.202 1.00 35.13 ? 463 HIS B CD2 1 ATOM 6873 C CE1 . HIS B 1 490 ? -6.767 21.692 36.816 1.00 35.58 ? 463 HIS B CE1 1 ATOM 6874 N NE2 . HIS B 1 490 ? -6.288 20.791 35.978 1.00 35.63 ? 463 HIS B NE2 1 ATOM 6875 N N . LEU B 1 491 ? -12.934 19.700 35.169 1.00 31.13 ? 464 LEU B N 1 ATOM 6876 C CA . LEU B 1 491 ? -14.370 19.948 35.292 1.00 32.00 ? 464 LEU B CA 1 ATOM 6877 C C . LEU B 1 491 ? -14.922 19.213 36.494 1.00 31.88 ? 464 LEU B C 1 ATOM 6878 O O . LEU B 1 491 ? -15.760 19.733 37.222 1.00 32.32 ? 464 LEU B O 1 ATOM 6879 C CB . LEU B 1 491 ? -15.126 19.501 34.018 1.00 30.26 ? 464 LEU B CB 1 ATOM 6880 C CG . LEU B 1 491 ? -15.038 20.483 32.875 1.00 27.73 ? 464 LEU B CG 1 ATOM 6881 C CD1 . LEU B 1 491 ? -15.446 19.832 31.578 1.00 30.50 ? 464 LEU B CD1 1 ATOM 6882 C CD2 . LEU B 1 491 ? -15.909 21.671 33.160 1.00 29.63 ? 464 LEU B CD2 1 ATOM 6883 N N . ARG B 1 492 ? -14.432 18.005 36.717 1.00 33.99 ? 465 ARG B N 1 ATOM 6884 C CA . ARG B 1 492 ? -14.852 17.257 37.893 1.00 36.38 ? 465 ARG B CA 1 ATOM 6885 C C . ARG B 1 492 ? -14.518 17.926 39.227 1.00 34.43 ? 465 ARG B C 1 ATOM 6886 O O . ARG B 1 492 ? -15.256 17.776 40.198 1.00 37.29 ? 465 ARG B O 1 ATOM 6887 C CB . ARG B 1 492 ? -14.180 15.918 37.927 1.00 39.84 ? 465 ARG B CB 1 ATOM 6888 C CG . ARG B 1 492 ? -14.700 14.938 36.921 1.00 47.03 ? 465 ARG B CG 1 ATOM 6889 C CD . ARG B 1 492 ? -14.272 13.613 37.482 1.00 54.97 ? 465 ARG B CD 1 ATOM 6890 N NE . ARG B 1 492 ? -14.370 12.526 36.543 1.00 57.88 ? 465 ARG B NE 1 ATOM 6891 C CZ . ARG B 1 492 ? -13.609 11.440 36.604 1.00 59.82 ? 465 ARG B CZ 1 ATOM 6892 N NH1 . ARG B 1 492 ? -12.637 11.316 37.526 1.00 57.00 ? 465 ARG B NH1 1 ATOM 6893 N NH2 . ARG B 1 492 ? -13.790 10.489 35.706 1.00 58.10 ? 465 ARG B NH2 1 ATOM 6894 N N . HIS B 1 493 ? -13.411 18.648 39.291 1.00 31.21 ? 466 HIS B N 1 ATOM 6895 C CA . HIS B 1 493 ? -13.011 19.277 40.558 1.00 35.37 ? 466 HIS B CA 1 ATOM 6896 C C . HIS B 1 493 ? -13.322 20.765 40.572 1.00 33.28 ? 466 HIS B C 1 ATOM 6897 O O . HIS B 1 493 ? -12.875 21.484 41.449 1.00 35.74 ? 466 HIS B O 1 ATOM 6898 C CB . HIS B 1 493 ? -11.525 19.030 40.831 1.00 37.63 ? 466 HIS B CB 1 ATOM 6899 C CG . HIS B 1 493 ? -11.185 17.598 41.066 1.00 43.56 ? 466 HIS B CG 1 ATOM 6900 N ND1 . HIS B 1 493 ? -10.733 17.123 42.281 1.00 50.85 ? 466 HIS B ND1 1 ATOM 6901 C CD2 . HIS B 1 493 ? -11.219 16.533 40.236 1.00 47.12 ? 466 HIS B CD2 1 ATOM 6902 C CE1 . HIS B 1 493 ? -10.497 15.826 42.183 1.00 50.60 ? 466 HIS B CE1 1 ATOM 6903 N NE2 . HIS B 1 493 ? -10.784 15.442 40.953 1.00 50.75 ? 466 HIS B NE2 1 ATOM 6904 N N . LEU B 1 494 ? -14.110 21.215 39.604 1.00 31.21 ? 467 LEU B N 1 ATOM 6905 C CA . LEU B 1 494 ? -14.322 22.616 39.385 1.00 30.74 ? 467 LEU B CA 1 ATOM 6906 C C . LEU B 1 494 ? -15.169 23.197 40.507 1.00 31.85 ? 467 LEU B C 1 ATOM 6907 O O . LEU B 1 494 ? -16.112 22.546 40.986 1.00 32.21 ? 467 LEU B O 1 ATOM 6908 C CB . LEU B 1 494 ? -14.991 22.837 38.013 1.00 29.57 ? 467 LEU B CB 1 ATOM 6909 C CG . LEU B 1 494 ? -15.282 24.279 37.650 1.00 30.61 ? 467 LEU B CG 1 ATOM 6910 C CD1 . LEU B 1 494 ? -13.963 25.014 37.442 1.00 33.96 ? 467 LEU B CD1 1 ATOM 6911 C CD2 . LEU B 1 494 ? -16.149 24.359 36.402 1.00 31.49 ? 467 LEU B CD2 1 ATOM 6912 N N . ASN B 1 495 ? -14.825 24.421 40.914 1.00 29.69 ? 468 ASN B N 1 ATOM 6913 C CA . ASN B 1 495 ? -15.629 25.150 41.875 1.00 33.24 ? 468 ASN B CA 1 ATOM 6914 C C . ASN B 1 495 ? -15.444 26.625 41.611 1.00 35.45 ? 468 ASN B C 1 ATOM 6915 O O . ASN B 1 495 ? -14.395 27.156 41.910 1.00 35.29 ? 468 ASN B O 1 ATOM 6916 C CB . ASN B 1 495 ? -15.187 24.804 43.294 1.00 35.44 ? 468 ASN B CB 1 ATOM 6917 C CG . ASN B 1 495 ? -16.035 25.471 44.357 1.00 37.47 ? 468 ASN B CG 1 ATOM 6918 O OD1 . ASN B 1 495 ? -16.891 26.300 44.068 1.00 37.70 ? 468 ASN B OD1 1 ATOM 6919 N ND2 . ASN B 1 495 ? -15.804 25.082 45.609 1.00 41.43 ? 468 ASN B ND2 1 ATOM 6920 N N . PHE B 1 496 ? -16.425 27.280 40.992 1.00 34.00 ? 469 PHE B N 1 ATOM 6921 C CA . PHE B 1 496 ? -16.311 28.713 40.746 1.00 32.92 ? 469 PHE B CA 1 ATOM 6922 C C . PHE B 1 496 ? -17.586 29.421 41.153 1.00 35.15 ? 469 PHE B C 1 ATOM 6923 O O . PHE B 1 496 ? -18.627 28.784 41.366 1.00 34.86 ? 469 PHE B O 1 ATOM 6924 C CB . PHE B 1 496 ? -15.951 29.003 39.284 1.00 33.91 ? 469 PHE B CB 1 ATOM 6925 C CG . PHE B 1 496 ? -17.093 28.790 38.304 1.00 35.81 ? 469 PHE B CG 1 ATOM 6926 C CD1 . PHE B 1 496 ? -17.345 27.533 37.782 1.00 34.51 ? 469 PHE B CD1 1 ATOM 6927 C CD2 . PHE B 1 496 ? -17.881 29.850 37.885 1.00 34.67 ? 469 PHE B CD2 1 ATOM 6928 C CE1 . PHE B 1 496 ? -18.376 27.328 36.876 1.00 33.85 ? 469 PHE B CE1 1 ATOM 6929 C CE2 . PHE B 1 496 ? -18.899 29.656 36.964 1.00 35.38 ? 469 PHE B CE2 1 ATOM 6930 C CZ . PHE B 1 496 ? -19.160 28.384 36.481 1.00 34.63 ? 469 PHE B CZ 1 ATOM 6931 N N . THR B 1 497 ? -17.489 30.736 41.258 1.00 34.42 ? 470 THR B N 1 ATOM 6932 C CA . THR B 1 497 ? -18.614 31.562 41.626 1.00 41.46 ? 470 THR B CA 1 ATOM 6933 C C . THR B 1 497 ? -19.130 32.169 40.349 1.00 39.18 ? 470 THR B C 1 ATOM 6934 O O . THR B 1 497 ? -18.358 32.723 39.590 1.00 42.27 ? 470 THR B O 1 ATOM 6935 C CB . THR B 1 497 ? -18.162 32.730 42.575 1.00 44.43 ? 470 THR B CB 1 ATOM 6936 O OG1 . THR B 1 497 ? -17.445 32.191 43.696 1.00 45.18 ? 470 THR B OG1 1 ATOM 6937 C CG2 . THR B 1 497 ? -19.347 33.597 43.102 1.00 44.56 ? 470 THR B CG2 1 ATOM 6938 N N . ASN B 1 498 ? -20.423 32.040 40.100 1.00 41.57 ? 471 ASN B N 1 ATOM 6939 C CA . ASN B 1 498 ? -21.007 32.580 38.874 1.00 43.95 ? 471 ASN B CA 1 ATOM 6940 C C . ASN B 1 498 ? -21.474 34.011 39.114 1.00 48.65 ? 471 ASN B C 1 ATOM 6941 O O . ASN B 1 498 ? -21.530 34.480 40.262 1.00 45.87 ? 471 ASN B O 1 ATOM 6942 C CB . ASN B 1 498 ? -22.131 31.677 38.313 1.00 38.52 ? 471 ASN B CB 1 ATOM 6943 C CG . ASN B 1 498 ? -23.345 31.568 39.223 1.00 41.18 ? 471 ASN B CG 1 ATOM 6944 O OD1 . ASN B 1 498 ? -23.596 32.412 40.086 1.00 43.93 ? 471 ASN B OD1 1 ATOM 6945 N ND2 . ASN B 1 498 ? -24.135 30.528 39.007 1.00 43.03 ? 471 ASN B ND2 1 ATOM 6946 N N . ASN B 1 499 ? -21.777 34.693 38.012 1.00 49.66 ? 472 ASN B N 1 ATOM 6947 C CA . ASN B 1 499 ? -22.238 36.079 38.020 1.00 47.34 ? 472 ASN B CA 1 ATOM 6948 C C . ASN B 1 499 ? -23.449 36.322 38.909 1.00 47.36 ? 472 ASN B C 1 ATOM 6949 O O . ASN B 1 499 ? -23.692 37.438 39.300 1.00 58.42 ? 472 ASN B O 1 ATOM 6950 C CB . ASN B 1 499 ? -22.501 36.582 36.587 1.00 49.49 ? 472 ASN B CB 1 ATOM 6951 C CG . ASN B 1 499 ? -23.662 35.866 35.897 1.00 50.55 ? 472 ASN B CG 1 ATOM 6952 O OD1 . ASN B 1 499 ? -24.652 36.496 35.543 1.00 46.95 ? 472 ASN B OD1 1 ATOM 6953 N ND2 . ASN B 1 499 ? -23.556 34.550 35.729 1.00 51.24 ? 472 ASN B ND2 1 ATOM 6954 N N . MET B 1 500 ? -24.207 35.288 39.243 1.00 49.46 ? 473 MET B N 1 ATOM 6955 C CA . MET B 1 500 ? -25.323 35.429 40.170 1.00 50.22 ? 473 MET B CA 1 ATOM 6956 C C . MET B 1 500 ? -24.896 35.242 41.632 1.00 55.18 ? 473 MET B C 1 ATOM 6957 O O . MET B 1 500 ? -25.753 35.169 42.520 1.00 57.72 ? 473 MET B O 1 ATOM 6958 C CB . MET B 1 500 ? -26.388 34.387 39.841 1.00 53.09 ? 473 MET B CB 1 ATOM 6959 C CG . MET B 1 500 ? -26.907 34.427 38.411 1.00 54.72 ? 473 MET B CG 1 ATOM 6960 S SD . MET B 1 500 ? -28.201 35.641 38.160 1.00 55.22 ? 473 MET B SD 1 ATOM 6961 C CE . MET B 1 500 ? -29.494 35.064 39.269 1.00 55.43 ? 473 MET B CE 1 ATOM 6962 N N . GLY B 1 501 ? -23.585 35.152 41.881 1.00 55.84 ? 474 GLY B N 1 ATOM 6963 C CA . GLY B 1 501 ? -23.043 34.931 43.229 1.00 60.35 ? 474 GLY B CA 1 ATOM 6964 C C . GLY B 1 501 ? -23.085 33.502 43.752 1.00 60.66 ? 474 GLY B C 1 ATOM 6965 O O . GLY B 1 501 ? -22.738 33.255 44.908 1.00 59.04 ? 474 GLY B O 1 ATOM 6966 N N . GLU B 1 502 ? -23.493 32.558 42.907 1.00 58.76 ? 475 GLU B N 1 ATOM 6967 C CA . GLU B 1 502 ? -23.666 31.183 43.331 1.00 58.17 ? 475 GLU B CA 1 ATOM 6968 C C . GLU B 1 502 ? -22.423 30.368 42.978 1.00 51.73 ? 475 GLU B C 1 ATOM 6969 O O . GLU B 1 502 ? -21.789 30.597 41.947 1.00 48.90 ? 475 GLU B O 1 ATOM 6970 C CB . GLU B 1 502 ? -24.886 30.579 42.648 1.00 66.63 ? 475 GLU B CB 1 ATOM 6971 C CG . GLU B 1 502 ? -26.164 31.379 42.791 1.00 73.76 ? 475 GLU B CG 1 ATOM 6972 C CD . GLU B 1 502 ? -26.764 31.255 44.174 1.00 80.68 ? 475 GLU B CD 1 ATOM 6973 O OE1 . GLU B 1 502 ? -26.670 30.162 44.779 1.00 87.08 ? 475 GLU B OE1 1 ATOM 6974 O OE2 . GLU B 1 502 ? -27.334 32.251 44.657 1.00 85.40 ? 475 GLU B OE2 1 ATOM 6975 N N . GLN B 1 503 ? -22.073 29.428 43.851 1.00 46.65 ? 476 GLN B N 1 ATOM 6976 C CA . GLN B 1 503 ? -20.971 28.500 43.598 1.00 43.50 ? 476 GLN B CA 1 ATOM 6977 C C . GLN B 1 503 ? -21.427 27.427 42.622 1.00 38.44 ? 476 GLN B C 1 ATOM 6978 O O . GLN B 1 503 ? -22.482 26.826 42.783 1.00 37.94 ? 476 GLN B O 1 ATOM 6979 C CB . GLN B 1 503 ? -20.501 27.828 44.901 1.00 45.69 ? 476 GLN B CB 1 ATOM 6980 C CG . GLN B 1 503 ? -19.794 28.758 45.870 1.00 47.48 ? 476 GLN B CG 1 ATOM 6981 C CD . GLN B 1 503 ? -18.585 29.414 45.245 1.00 48.57 ? 476 GLN B CD 1 ATOM 6982 O OE1 . GLN B 1 503 ? -17.660 28.732 44.798 1.00 49.69 ? 476 GLN B OE1 1 ATOM 6983 N NE2 . GLN B 1 503 ? -18.579 30.741 45.200 1.00 49.77 ? 476 GLN B NE2 1 ATOM 6984 N N . VAL B 1 504 ? -20.632 27.178 41.603 1.00 37.03 ? 477 VAL B N 1 ATOM 6985 C CA . VAL B 1 504 ? -20.938 26.109 40.684 1.00 34.21 ? 477 VAL B CA 1 ATOM 6986 C C . VAL B 1 504 ? -19.924 24.997 40.868 1.00 32.68 ? 477 VAL B C 1 ATOM 6987 O O . VAL B 1 504 ? -18.730 25.218 40.643 1.00 30.26 ? 477 VAL B O 1 ATOM 6988 C CB . VAL B 1 504 ? -20.944 26.613 39.235 1.00 34.09 ? 477 VAL B CB 1 ATOM 6989 C CG1 . VAL B 1 504 ? -21.177 25.466 38.267 1.00 32.48 ? 477 VAL B CG1 1 ATOM 6990 C CG2 . VAL B 1 504 ? -22.016 27.684 39.050 1.00 37.92 ? 477 VAL B CG2 1 ATOM 6991 N N . THR B 1 505 ? -20.421 23.813 41.251 1.00 31.86 ? 478 THR B N 1 ATOM 6992 C CA . THR B 1 505 ? -19.655 22.581 41.322 1.00 32.14 ? 478 THR B CA 1 ATOM 6993 C C . THR B 1 505 ? -20.533 21.442 40.851 1.00 31.58 ? 478 THR B C 1 ATOM 6994 O O . THR B 1 505 ? -21.747 21.542 40.911 1.00 32.75 ? 478 THR B O 1 ATOM 6995 C CB . THR B 1 505 ? -19.252 22.246 42.771 1.00 35.74 ? 478 THR B CB 1 ATOM 6996 O OG1 . THR B 1 505 ? -20.428 22.133 43.575 1.00 35.36 ? 478 THR B OG1 1 ATOM 6997 C CG2 . THR B 1 505 ? -18.376 23.320 43.379 1.00 36.50 ? 478 THR B CG2 1 ATOM 6998 N N . PHE B 1 506 ? -19.924 20.351 40.406 1.00 30.87 ? 479 PHE B N 1 ATOM 6999 C CA . PHE B 1 506 ? -20.649 19.175 39.938 1.00 31.91 ? 479 PHE B CA 1 ATOM 7000 C C . PHE B 1 506 ? -20.470 18.067 40.931 1.00 33.18 ? 479 PHE B C 1 ATOM 7001 O O . PHE B 1 506 ? -19.387 17.898 41.438 1.00 35.96 ? 479 PHE B O 1 ATOM 7002 C CB . PHE B 1 506 ? -20.146 18.731 38.547 1.00 31.85 ? 479 PHE B CB 1 ATOM 7003 C CG . PHE B 1 506 ? -20.288 19.795 37.502 1.00 31.33 ? 479 PHE B CG 1 ATOM 7004 C CD1 . PHE B 1 506 ? -21.529 20.063 36.930 1.00 31.27 ? 479 PHE B CD1 1 ATOM 7005 C CD2 . PHE B 1 506 ? -19.205 20.563 37.127 1.00 31.21 ? 479 PHE B CD2 1 ATOM 7006 C CE1 . PHE B 1 506 ? -21.677 21.063 35.987 1.00 31.60 ? 479 PHE B CE1 1 ATOM 7007 C CE2 . PHE B 1 506 ? -19.340 21.573 36.186 1.00 32.34 ? 479 PHE B CE2 1 ATOM 7008 C CZ . PHE B 1 506 ? -20.575 21.821 35.608 1.00 33.54 ? 479 PHE B CZ 1 ATOM 7009 N N . ASP B 1 507 ? -21.527 17.307 41.217 1.00 35.87 ? 480 ASP B N 1 ATOM 7010 C CA . ASP B 1 507 ? -21.413 16.208 42.172 1.00 36.81 ? 480 ASP B CA 1 ATOM 7011 C C . ASP B 1 507 ? -20.723 15.020 41.522 1.00 34.99 ? 480 ASP B C 1 ATOM 7012 O O . ASP B 1 507 ? -20.305 15.086 40.350 1.00 31.87 ? 480 ASP B O 1 ATOM 7013 C CB . ASP B 1 507 ? -22.784 15.837 42.782 1.00 38.39 ? 480 ASP B CB 1 ATOM 7014 C CG . ASP B 1 507 ? -23.766 15.185 41.772 1.00 38.56 ? 480 ASP B CG 1 ATOM 7015 O OD1 . ASP B 1 507 ? -23.378 14.674 40.694 1.00 33.56 ? 480 ASP B OD1 1 ATOM 7016 O OD2 . ASP B 1 507 ? -24.960 15.177 42.108 1.00 40.81 ? 480 ASP B OD2 1 ATOM 7017 N N . GLU B 1 508 ? -20.604 13.934 42.275 1.00 37.01 ? 481 GLU B N 1 ATOM 7018 C CA . GLU B 1 508 ? -19.961 12.697 41.786 1.00 39.52 ? 481 GLU B CA 1 ATOM 7019 C C . GLU B 1 508 ? -20.607 12.086 40.525 1.00 40.07 ? 481 GLU B C 1 ATOM 7020 O O . GLU B 1 508 ? -19.940 11.373 39.769 1.00 46.64 ? 481 GLU B O 1 ATOM 7021 C CB . GLU B 1 508 ? -19.950 11.644 42.912 1.00 37.82 ? 481 GLU B CB 1 HETATM 7022 N N . CSO B 1 509 ? -21.882 12.378 40.284 1.00 37.84 ? 482 CSO B N 1 HETATM 7023 C CA . CSO B 1 509 ? -22.567 11.917 39.064 1.00 40.14 ? 482 CSO B CA 1 HETATM 7024 C CB . CSO B 1 509 ? -24.018 11.588 39.411 1.00 44.62 ? 482 CSO B CB 1 HETATM 7025 S SG . CSO B 1 509 ? -24.038 10.217 40.557 1.00 54.32 ? 482 CSO B SG 1 HETATM 7026 C C . CSO B 1 509 ? -22.515 12.908 37.914 1.00 36.94 ? 482 CSO B C 1 HETATM 7027 O O . CSO B 1 509 ? -23.140 12.689 36.884 1.00 35.25 ? 482 CSO B O 1 HETATM 7028 O OD . CSO B 1 509 ? -24.550 11.108 41.977 1.00 56.18 ? 482 CSO B OD 1 ATOM 7029 N N . GLY B 1 510 ? -21.771 14.002 38.064 1.00 33.45 ? 483 GLY B N 1 ATOM 7030 C CA . GLY B 1 510 ? -21.719 15.042 37.042 1.00 29.79 ? 483 GLY B CA 1 ATOM 7031 C C . GLY B 1 510 ? -22.944 15.941 37.024 1.00 29.22 ? 483 GLY B C 1 ATOM 7032 O O . GLY B 1 510 ? -23.135 16.694 36.091 1.00 31.75 ? 483 GLY B O 1 ATOM 7033 N N . ASP B 1 511 ? -23.728 15.928 38.092 1.00 29.30 ? 484 ASP B N 1 ATOM 7034 C CA . ASP B 1 511 ? -24.958 16.712 38.183 1.00 30.88 ? 484 ASP B CA 1 ATOM 7035 C C . ASP B 1 511 ? -24.750 18.026 38.914 1.00 31.68 ? 484 ASP B C 1 ATOM 7036 O O . ASP B 1 511 ? -23.915 18.166 39.828 1.00 34.24 ? 484 ASP B O 1 ATOM 7037 C CB . ASP B 1 511 ? -26.053 15.888 38.896 1.00 34.31 ? 484 ASP B CB 1 ATOM 7038 C CG . ASP B 1 511 ? -26.511 14.661 38.071 1.00 37.80 ? 484 ASP B CG 1 ATOM 7039 O OD1 . ASP B 1 511 ? -26.417 14.689 36.828 1.00 40.28 ? 484 ASP B OD1 1 ATOM 7040 O OD2 . ASP B 1 511 ? -26.957 13.652 38.658 1.00 42.63 ? 484 ASP B OD2 1 ATOM 7041 N N . LEU B 1 512 ? -25.546 18.998 38.538 1.00 31.41 ? 485 LEU B N 1 ATOM 7042 C CA . LEU B 1 512 ? -25.507 20.274 39.179 1.00 34.56 ? 485 LEU B CA 1 ATOM 7043 C C . LEU B 1 512 ? -26.876 20.490 39.764 1.00 36.07 ? 485 LEU B C 1 ATOM 7044 O O . LEU B 1 512 ? -27.857 20.599 39.040 1.00 35.30 ? 485 LEU B O 1 ATOM 7045 C CB . LEU B 1 512 ? -25.247 21.366 38.172 1.00 34.93 ? 485 LEU B CB 1 ATOM 7046 C CG . LEU B 1 512 ? -25.328 22.762 38.745 1.00 37.93 ? 485 LEU B CG 1 ATOM 7047 C CD1 . LEU B 1 512 ? -24.195 22.994 39.730 1.00 41.78 ? 485 LEU B CD1 1 ATOM 7048 C CD2 . LEU B 1 512 ? -25.270 23.774 37.633 1.00 38.05 ? 485 LEU B CD2 1 ATOM 7049 N N . VAL B 1 513 ? -26.911 20.614 41.070 1.00 38.76 ? 486 VAL B N 1 ATOM 7050 C CA . VAL B 1 513 ? -28.150 20.655 41.832 1.00 40.79 ? 486 VAL B CA 1 ATOM 7051 C C . VAL B 1 513 ? -28.796 22.013 41.624 1.00 39.03 ? 486 VAL B C 1 ATOM 7052 O O . VAL B 1 513 ? -28.111 23.010 41.402 1.00 41.68 ? 486 VAL B O 1 ATOM 7053 C CB . VAL B 1 513 ? -27.882 20.379 43.333 1.00 44.45 ? 486 VAL B CB 1 ATOM 7054 C CG1 . VAL B 1 513 ? -27.155 19.053 43.503 1.00 46.73 ? 486 VAL B CG1 1 ATOM 7055 C CG2 . VAL B 1 513 ? -27.051 21.491 43.957 1.00 48.07 ? 486 VAL B CG2 1 ATOM 7056 N N . GLY B 1 514 ? -30.115 22.047 41.689 1.00 37.72 ? 487 GLY B N 1 ATOM 7057 C CA . GLY B 1 514 ? -30.852 23.286 41.459 1.00 37.98 ? 487 GLY B CA 1 ATOM 7058 C C . GLY B 1 514 ? -32.256 23.149 42.002 1.00 39.94 ? 487 GLY B C 1 ATOM 7059 O O . GLY B 1 514 ? -32.738 22.026 42.215 1.00 36.60 ? 487 GLY B O 1 ATOM 7060 N N . ASN B 1 515 ? -32.890 24.287 42.262 1.00 39.28 ? 488 ASN B N 1 ATOM 7061 C CA . ASN B 1 515 ? -34.298 24.343 42.659 1.00 41.29 ? 488 ASN B CA 1 ATOM 7062 C C . ASN B 1 515 ? -35.164 24.586 41.420 1.00 37.74 ? 488 ASN B C 1 ATOM 7063 O O . ASN B 1 515 ? -34.632 24.749 40.334 1.00 35.85 ? 488 ASN B O 1 ATOM 7064 C CB . ASN B 1 515 ? -34.501 25.474 43.653 1.00 44.59 ? 488 ASN B CB 1 ATOM 7065 C CG . ASN B 1 515 ? -33.845 25.213 45.005 1.00 44.05 ? 488 ASN B CG 1 ATOM 7066 O OD1 . ASN B 1 515 ? -33.856 24.094 45.523 1.00 40.71 ? 488 ASN B OD1 1 ATOM 7067 N ND2 . ASN B 1 515 ? -33.285 26.274 45.589 1.00 49.80 ? 488 ASN B ND2 1 ATOM 7068 N N . TYR B 1 516 ? -36.485 24.593 41.582 1.00 33.98 ? 489 TYR B N 1 ATOM 7069 C CA . TYR B 1 516 ? -37.403 24.907 40.469 1.00 34.07 ? 489 TYR B CA 1 ATOM 7070 C C . TYR B 1 516 ? -38.329 26.055 40.824 1.00 34.28 ? 489 TYR B C 1 ATOM 7071 O O . TYR B 1 516 ? -38.670 26.239 41.993 1.00 35.92 ? 489 TYR B O 1 ATOM 7072 C CB . TYR B 1 516 ? -38.276 23.696 40.102 1.00 33.86 ? 489 TYR B CB 1 ATOM 7073 C CG . TYR B 1 516 ? -37.521 22.451 39.697 1.00 31.69 ? 489 TYR B CG 1 ATOM 7074 C CD1 . TYR B 1 516 ? -36.991 22.306 38.401 1.00 33.39 ? 489 TYR B CD1 1 ATOM 7075 C CD2 . TYR B 1 516 ? -37.369 21.392 40.586 1.00 32.57 ? 489 TYR B CD2 1 ATOM 7076 C CE1 . TYR B 1 516 ? -36.307 21.147 38.028 1.00 32.80 ? 489 TYR B CE1 1 ATOM 7077 C CE2 . TYR B 1 516 ? -36.681 20.241 40.233 1.00 32.13 ? 489 TYR B CE2 1 ATOM 7078 C CZ . TYR B 1 516 ? -36.156 20.118 38.948 1.00 33.72 ? 489 TYR B CZ 1 ATOM 7079 O OH . TYR B 1 516 ? -35.472 18.977 38.622 1.00 32.61 ? 489 TYR B OH 1 ATOM 7080 N N . SER B 1 517 ? -38.690 26.836 39.814 1.00 35.78 ? 490 SER B N 1 ATOM 7081 C CA . SER B 1 517 ? -39.775 27.784 39.880 1.00 35.51 ? 490 SER B CA 1 ATOM 7082 C C . SER B 1 517 ? -41.027 27.042 39.452 1.00 37.36 ? 490 SER B C 1 ATOM 7083 O O . SER B 1 517 ? -40.936 26.092 38.666 1.00 32.00 ? 490 SER B O 1 ATOM 7084 C CB . SER B 1 517 ? -39.554 28.950 38.929 1.00 37.00 ? 490 SER B CB 1 ATOM 7085 O OG . SER B 1 517 ? -38.506 29.748 39.403 1.00 47.49 ? 490 SER B OG 1 ATOM 7086 N N . ILE B 1 518 ? -42.189 27.496 39.938 1.00 33.78 ? 491 ILE B N 1 ATOM 7087 C CA . ILE B 1 518 ? -43.464 26.951 39.515 1.00 33.38 ? 491 ILE B CA 1 ATOM 7088 C C . ILE B 1 518 ? -44.221 28.029 38.791 1.00 35.83 ? 491 ILE B C 1 ATOM 7089 O O . ILE B 1 518 ? -44.394 29.151 39.319 1.00 37.62 ? 491 ILE B O 1 ATOM 7090 C CB . ILE B 1 518 ? -44.271 26.401 40.700 1.00 34.33 ? 491 ILE B CB 1 ATOM 7091 C CG1 . ILE B 1 518 ? -43.470 25.309 41.410 1.00 36.30 ? 491 ILE B CG1 1 ATOM 7092 C CG2 . ILE B 1 518 ? -45.594 25.805 40.233 1.00 33.42 ? 491 ILE B CG2 1 ATOM 7093 C CD1 . ILE B 1 518 ? -44.000 24.953 42.779 1.00 38.11 ? 491 ILE B CD1 1 ATOM 7094 N N . ILE B 1 519 ? -44.675 27.708 37.581 1.00 33.34 ? 492 ILE B N 1 ATOM 7095 C CA . ILE B 1 519 ? -45.346 28.693 36.731 1.00 32.60 ? 492 ILE B CA 1 ATOM 7096 C C . ILE B 1 519 ? -46.758 28.240 36.359 1.00 33.51 ? 492 ILE B C 1 ATOM 7097 O O . ILE B 1 519 ? -47.110 27.061 36.500 1.00 31.94 ? 492 ILE B O 1 ATOM 7098 C CB . ILE B 1 519 ? -44.543 29.003 35.454 1.00 34.49 ? 492 ILE B CB 1 ATOM 7099 C CG1 . ILE B 1 519 ? -44.307 27.731 34.648 1.00 36.28 ? 492 ILE B CG1 1 ATOM 7100 C CG2 . ILE B 1 519 ? -43.230 29.698 35.802 1.00 33.77 ? 492 ILE B CG2 1 ATOM 7101 C CD1 . ILE B 1 519 ? -43.893 27.997 33.217 1.00 39.07 ? 492 ILE B CD1 1 ATOM 7102 N N . ASN B 1 520 ? -47.560 29.176 35.864 1.00 33.47 ? 493 ASN B N 1 ATOM 7103 C CA . ASN B 1 520 ? -48.980 28.931 35.612 1.00 33.37 ? 493 ASN B CA 1 ATOM 7104 C C . ASN B 1 520 ? -49.399 29.696 34.375 1.00 34.62 ? 493 ASN B C 1 ATOM 7105 O O . ASN B 1 520 ? -49.011 30.855 34.203 1.00 37.14 ? 493 ASN B O 1 ATOM 7106 C CB . ASN B 1 520 ? -49.763 29.380 36.824 1.00 35.46 ? 493 ASN B CB 1 ATOM 7107 C CG . ASN B 1 520 ? -51.252 29.053 36.732 1.00 38.22 ? 493 ASN B CG 1 ATOM 7108 O OD1 . ASN B 1 520 ? -51.701 28.044 36.160 1.00 38.89 ? 493 ASN B OD1 1 ATOM 7109 N ND2 . ASN B 1 520 ? -52.018 29.873 37.370 1.00 34.86 ? 493 ASN B ND2 1 ATOM 7110 N N . TRP B 1 521 ? -50.148 29.056 33.488 1.00 32.97 ? 494 TRP B N 1 ATOM 7111 C CA . TRP B 1 521 ? -50.405 29.655 32.183 1.00 35.90 ? 494 TRP B CA 1 ATOM 7112 C C . TRP B 1 521 ? -51.627 30.597 32.232 1.00 38.82 ? 494 TRP B C 1 ATOM 7113 O O . TRP B 1 521 ? -52.774 30.134 32.364 1.00 35.67 ? 494 TRP B O 1 ATOM 7114 C CB . TRP B 1 521 ? -50.645 28.565 31.164 1.00 37.52 ? 494 TRP B CB 1 ATOM 7115 C CG . TRP B 1 521 ? -49.420 27.818 30.787 1.00 38.91 ? 494 TRP B CG 1 ATOM 7116 C CD1 . TRP B 1 521 ? -48.251 27.738 31.490 1.00 36.43 ? 494 TRP B CD1 1 ATOM 7117 C CD2 . TRP B 1 521 ? -49.261 26.981 29.645 1.00 37.92 ? 494 TRP B CD2 1 ATOM 7118 N NE1 . TRP B 1 521 ? -47.362 26.944 30.829 1.00 38.62 ? 494 TRP B NE1 1 ATOM 7119 C CE2 . TRP B 1 521 ? -47.956 26.453 29.700 1.00 37.45 ? 494 TRP B CE2 1 ATOM 7120 C CE3 . TRP B 1 521 ? -50.085 26.641 28.565 1.00 38.38 ? 494 TRP B CE3 1 ATOM 7121 C CZ2 . TRP B 1 521 ? -47.452 25.605 28.725 1.00 37.46 ? 494 TRP B CZ2 1 ATOM 7122 C CZ3 . TRP B 1 521 ? -49.581 25.793 27.591 1.00 35.93 ? 494 TRP B CZ3 1 ATOM 7123 C CH2 . TRP B 1 521 ? -48.270 25.286 27.684 1.00 36.26 ? 494 TRP B CH2 1 ATOM 7124 N N . HIS B 1 522 ? -51.358 31.897 32.140 1.00 41.85 ? 495 HIS B N 1 ATOM 7125 C CA . HIS B 1 522 ? -52.395 32.946 32.070 1.00 45.68 ? 495 HIS B CA 1 ATOM 7126 C C . HIS B 1 522 ? -52.498 33.493 30.658 1.00 47.43 ? 495 HIS B C 1 ATOM 7127 O O . HIS B 1 522 ? -51.598 33.288 29.837 1.00 48.29 ? 495 HIS B O 1 ATOM 7128 C CB . HIS B 1 522 ? -52.018 34.131 32.949 1.00 44.64 ? 495 HIS B CB 1 ATOM 7129 C CG . HIS B 1 522 ? -52.038 33.847 34.409 1.00 47.85 ? 495 HIS B CG 1 ATOM 7130 N ND1 . HIS B 1 522 ? -52.220 32.586 34.930 1.00 52.12 ? 495 HIS B ND1 1 ATOM 7131 C CD2 . HIS B 1 522 ? -51.837 34.664 35.464 1.00 50.73 ? 495 HIS B CD2 1 ATOM 7132 C CE1 . HIS B 1 522 ? -52.164 32.649 36.246 1.00 49.68 ? 495 HIS B CE1 1 ATOM 7133 N NE2 . HIS B 1 522 ? -51.934 33.896 36.595 1.00 52.34 ? 495 HIS B NE2 1 ATOM 7134 N N . LEU B 1 523 ? -53.586 34.211 30.400 1.00 51.86 ? 496 LEU B N 1 ATOM 7135 C CA . LEU B 1 523 ? -53.810 34.909 29.134 1.00 54.18 ? 496 LEU B CA 1 ATOM 7136 C C . LEU B 1 523 ? -53.549 36.382 29.386 1.00 54.61 ? 496 LEU B C 1 ATOM 7137 O O . LEU B 1 523 ? -54.019 36.926 30.375 1.00 56.44 ? 496 LEU B O 1 ATOM 7138 C CB . LEU B 1 523 ? -55.252 34.733 28.682 1.00 54.79 ? 496 LEU B CB 1 ATOM 7139 C CG . LEU B 1 523 ? -55.542 34.164 27.290 1.00 56.51 ? 496 LEU B CG 1 ATOM 7140 C CD1 . LEU B 1 523 ? -56.975 34.507 26.913 1.00 55.07 ? 496 LEU B CD1 1 ATOM 7141 C CD2 . LEU B 1 523 ? -54.598 34.647 26.207 1.00 56.48 ? 496 LEU B CD2 1 ATOM 7142 N N . SER B 1 524 ? -52.780 37.026 28.520 1.00 61.30 ? 497 SER B N 1 ATOM 7143 C CA . SER B 1 524 ? -52.497 38.457 28.685 1.00 68.35 ? 497 SER B CA 1 ATOM 7144 C C . SER B 1 524 ? -53.746 39.283 28.337 1.00 68.85 ? 497 SER B C 1 ATOM 7145 O O . SER B 1 524 ? -54.336 39.093 27.267 1.00 63.02 ? 497 SER B O 1 ATOM 7146 C CB . SER B 1 524 ? -51.325 38.882 27.794 1.00 73.66 ? 497 SER B CB 1 ATOM 7147 O OG . SER B 1 524 ? -50.920 40.218 28.058 1.00 74.20 ? 497 SER B OG 1 ATOM 7148 N N . PRO B 1 525 ? -54.164 40.186 29.243 1.00 71.77 ? 498 PRO B N 1 ATOM 7149 C CA . PRO B 1 525 ? -55.295 41.054 28.915 1.00 76.08 ? 498 PRO B CA 1 ATOM 7150 C C . PRO B 1 525 ? -54.908 42.105 27.859 1.00 77.19 ? 498 PRO B C 1 ATOM 7151 O O . PRO B 1 525 ? -55.729 42.454 27.015 1.00 78.81 ? 498 PRO B O 1 ATOM 7152 C CB . PRO B 1 525 ? -55.649 41.698 30.258 1.00 75.59 ? 498 PRO B CB 1 ATOM 7153 C CG . PRO B 1 525 ? -54.374 41.694 31.035 1.00 76.32 ? 498 PRO B CG 1 ATOM 7154 C CD . PRO B 1 525 ? -53.575 40.512 30.557 1.00 75.37 ? 498 PRO B CD 1 ATOM 7155 N N . GLU B 1 526 ? -53.658 42.566 27.894 1.00 79.23 ? 499 GLU B N 1 ATOM 7156 C CA . GLU B 1 526 ? -53.128 43.470 26.879 1.00 78.98 ? 499 GLU B CA 1 ATOM 7157 C C . GLU B 1 526 ? -52.972 42.734 25.547 1.00 84.08 ? 499 GLU B C 1 ATOM 7158 O O . GLU B 1 526 ? -53.517 43.141 24.524 1.00 90.04 ? 499 GLU B O 1 ATOM 7159 C CB . GLU B 1 526 ? -51.771 44.036 27.322 1.00 74.35 ? 499 GLU B CB 1 ATOM 7160 N N . ASP B 1 527 ? -52.273 41.607 25.595 1.00 88.10 ? 500 ASP B N 1 ATOM 7161 C CA . ASP B 1 527 ? -51.653 40.995 24.423 1.00 83.17 ? 500 ASP B CA 1 ATOM 7162 C C . ASP B 1 527 ? -52.484 39.889 23.748 1.00 78.45 ? 500 ASP B C 1 ATOM 7163 O O . ASP B 1 527 ? -52.337 39.650 22.547 1.00 80.60 ? 500 ASP B O 1 ATOM 7164 C CB . ASP B 1 527 ? -50.301 40.419 24.868 1.00 82.54 ? 500 ASP B CB 1 ATOM 7165 C CG . ASP B 1 527 ? -49.256 40.466 23.791 1.00 84.62 ? 500 ASP B CG 1 ATOM 7166 O OD1 . ASP B 1 527 ? -49.610 40.584 22.598 1.00 80.73 ? 500 ASP B OD1 1 ATOM 7167 O OD2 . ASP B 1 527 ? -48.063 40.369 24.153 1.00 87.28 ? 500 ASP B OD2 1 ATOM 7168 N N . GLY B 1 528 ? -53.332 39.205 24.515 1.00 69.28 ? 501 GLY B N 1 ATOM 7169 C CA . GLY B 1 528 ? -53.997 37.984 24.040 1.00 65.96 ? 501 GLY B CA 1 ATOM 7170 C C . GLY B 1 528 ? -53.089 36.745 24.038 1.00 63.23 ? 501 GLY B C 1 ATOM 7171 O O . GLY B 1 528 ? -53.528 35.633 23.695 1.00 59.23 ? 501 GLY B O 1 ATOM 7172 N N . SER B 1 529 ? -51.824 36.921 24.422 1.00 61.71 ? 502 SER B N 1 ATOM 7173 C CA . SER B 1 529 ? -50.853 35.828 24.392 1.00 60.87 ? 502 SER B CA 1 ATOM 7174 C C . SER B 1 529 ? -50.792 35.143 25.754 1.00 59.50 ? 502 SER B C 1 ATOM 7175 O O . SER B 1 529 ? -51.276 35.679 26.764 1.00 58.65 ? 502 SER B O 1 ATOM 7176 C CB . SER B 1 529 ? -49.470 36.351 24.024 1.00 61.85 ? 502 SER B CB 1 ATOM 7177 O OG . SER B 1 529 ? -48.957 37.199 25.041 1.00 67.91 ? 502 SER B OG 1 ATOM 7178 N N . ILE B 1 530 ? -50.193 33.958 25.774 1.00 57.21 ? 503 ILE B N 1 ATOM 7179 C CA . ILE B 1 530 ? -50.053 33.198 27.004 1.00 53.55 ? 503 ILE B CA 1 ATOM 7180 C C . ILE B 1 530 ? -48.870 33.745 27.818 1.00 51.26 ? 503 ILE B C 1 ATOM 7181 O O . ILE B 1 530 ? -47.795 33.980 27.297 1.00 50.06 ? 503 ILE B O 1 ATOM 7182 C CB . ILE B 1 530 ? -49.978 31.685 26.700 1.00 56.24 ? 503 ILE B CB 1 ATOM 7183 C CG1 . ILE B 1 530 ? -51.331 31.255 26.109 1.00 55.08 ? 503 ILE B CG1 1 ATOM 7184 C CG2 . ILE B 1 530 ? -49.648 30.881 27.953 1.00 56.21 ? 503 ILE B CG2 1 ATOM 7185 C CD1 . ILE B 1 530 ? -51.438 29.811 25.677 1.00 57.19 ? 503 ILE B CD1 1 ATOM 7186 N N . VAL B 1 531 ? -49.113 33.990 29.096 1.00 46.15 ? 504 VAL B N 1 ATOM 7187 C CA . VAL B 1 531 ? -48.127 34.541 30.007 1.00 46.46 ? 504 VAL B CA 1 ATOM 7188 C C . VAL B 1 531 ? -47.814 33.453 31.013 1.00 43.92 ? 504 VAL B C 1 ATOM 7189 O O . VAL B 1 531 ? -48.727 32.793 31.489 1.00 42.14 ? 504 VAL B O 1 ATOM 7190 C CB . VAL B 1 531 ? -48.721 35.732 30.796 1.00 49.31 ? 504 VAL B CB 1 ATOM 7191 C CG1 . VAL B 1 531 ? -47.693 36.330 31.737 1.00 51.31 ? 504 VAL B CG1 1 ATOM 7192 C CG2 . VAL B 1 531 ? -49.261 36.795 29.855 1.00 51.20 ? 504 VAL B CG2 1 ATOM 7193 N N . PHE B 1 532 ? -46.538 33.283 31.327 1.00 43.00 ? 505 PHE B N 1 ATOM 7194 C CA . PHE B 1 532 ? -46.082 32.285 32.283 1.00 44.72 ? 505 PHE B CA 1 ATOM 7195 C C . PHE B 1 532 ? -45.884 32.937 33.628 1.00 44.92 ? 505 PHE B C 1 ATOM 7196 O O . PHE B 1 532 ? -44.808 33.441 33.929 1.00 47.19 ? 505 PHE B O 1 ATOM 7197 C CB . PHE B 1 532 ? -44.767 31.646 31.819 1.00 46.32 ? 505 PHE B CB 1 ATOM 7198 C CG . PHE B 1 532 ? -44.856 31.011 30.463 1.00 46.03 ? 505 PHE B CG 1 ATOM 7199 C CD1 . PHE B 1 532 ? -45.848 30.089 30.186 1.00 43.43 ? 505 PHE B CD1 1 ATOM 7200 C CD2 . PHE B 1 532 ? -43.938 31.320 29.472 1.00 50.52 ? 505 PHE B CD2 1 ATOM 7201 C CE1 . PHE B 1 532 ? -45.934 29.494 28.947 1.00 44.29 ? 505 PHE B CE1 1 ATOM 7202 C CE2 . PHE B 1 532 ? -44.020 30.722 28.221 1.00 50.14 ? 505 PHE B CE2 1 ATOM 7203 C CZ . PHE B 1 532 ? -45.022 29.804 27.959 1.00 47.07 ? 505 PHE B CZ 1 ATOM 7204 N N . LYS B 1 533 ? -46.931 32.924 34.442 1.00 46.18 ? 506 LYS B N 1 ATOM 7205 C CA . LYS B 1 533 ? -46.899 33.612 35.722 1.00 46.54 ? 506 LYS B CA 1 ATOM 7206 C C . LYS B 1 533 ? -46.197 32.705 36.739 1.00 43.30 ? 506 LYS B C 1 ATOM 7207 O O . LYS B 1 533 ? -46.563 31.540 36.878 1.00 38.64 ? 506 LYS B O 1 ATOM 7208 C CB . LYS B 1 533 ? -48.339 33.951 36.158 1.00 51.79 ? 506 LYS B CB 1 ATOM 7209 C CG . LYS B 1 533 ? -48.520 35.248 36.926 1.00 61.70 ? 506 LYS B CG 1 ATOM 7210 C CD . LYS B 1 533 ? -47.665 35.279 38.183 1.00 69.92 ? 506 LYS B CD 1 ATOM 7211 C CE . LYS B 1 533 ? -48.306 36.067 39.321 1.00 77.16 ? 506 LYS B CE 1 ATOM 7212 N NZ . LYS B 1 533 ? -48.436 37.526 39.050 1.00 81.82 ? 506 LYS B NZ 1 ATOM 7213 N N . GLU B 1 534 ? -45.215 33.244 37.467 1.00 41.27 ? 507 GLU B N 1 ATOM 7214 C CA . GLU B 1 534 ? -44.631 32.548 38.610 1.00 42.65 ? 507 GLU B CA 1 ATOM 7215 C C . GLU B 1 534 ? -45.569 32.549 39.809 1.00 39.52 ? 507 GLU B C 1 ATOM 7216 O O . GLU B 1 534 ? -46.033 33.591 40.270 1.00 41.84 ? 507 GLU B O 1 ATOM 7217 C CB . GLU B 1 534 ? -43.258 33.117 38.992 1.00 49.67 ? 507 GLU B CB 1 ATOM 7218 C CG . GLU B 1 534 ? -42.195 32.869 37.916 1.00 56.44 ? 507 GLU B CG 1 ATOM 7219 C CD . GLU B 1 534 ? -40.757 32.954 38.427 1.00 68.24 ? 507 GLU B CD 1 ATOM 7220 O OE1 . GLU B 1 534 ? -40.546 33.629 39.458 1.00 72.41 ? 507 GLU B OE1 1 ATOM 7221 O OE2 . GLU B 1 534 ? -39.840 32.350 37.797 1.00 70.62 ? 507 GLU B OE2 1 ATOM 7222 N N . VAL B 1 535 ? -45.869 31.362 40.305 1.00 36.21 ? 508 VAL B N 1 ATOM 7223 C CA . VAL B 1 535 ? -46.801 31.221 41.409 1.00 35.60 ? 508 VAL B CA 1 ATOM 7224 C C . VAL B 1 535 ? -46.180 30.498 42.591 1.00 34.73 ? 508 VAL B C 1 ATOM 7225 O O . VAL B 1 535 ? -46.849 30.244 43.591 1.00 37.94 ? 508 VAL B O 1 ATOM 7226 C CB . VAL B 1 535 ? -48.082 30.495 40.955 1.00 34.91 ? 508 VAL B CB 1 ATOM 7227 C CG1 . VAL B 1 535 ? -48.784 31.287 39.856 1.00 33.95 ? 508 VAL B CG1 1 ATOM 7228 C CG2 . VAL B 1 535 ? -47.790 29.082 40.471 1.00 37.31 ? 508 VAL B CG2 1 ATOM 7229 N N . GLY B 1 536 ? -44.907 30.140 42.484 1.00 35.16 ? 509 GLY B N 1 ATOM 7230 C CA . GLY B 1 536 ? -44.272 29.356 43.546 1.00 33.75 ? 509 GLY B CA 1 ATOM 7231 C C . GLY B 1 536 ? -42.864 28.889 43.222 1.00 32.28 ? 509 GLY B C 1 ATOM 7232 O O . GLY B 1 536 ? -42.316 29.225 42.204 1.00 28.86 ? 509 GLY B O 1 ATOM 7233 N N . TYR B 1 537 ? -42.303 28.074 44.099 1.00 34.14 ? 510 TYR B N 1 ATOM 7234 C CA . TYR B 1 537 ? -41.015 27.480 43.869 1.00 36.23 ? 510 TYR B CA 1 ATOM 7235 C C . TYR B 1 537 ? -40.931 26.195 44.669 1.00 34.74 ? 510 TYR B C 1 ATOM 7236 O O . TYR B 1 537 ? -41.746 25.928 45.553 1.00 33.65 ? 510 TYR B O 1 ATOM 7237 C CB . TYR B 1 537 ? -39.855 28.455 44.195 1.00 41.07 ? 510 TYR B CB 1 ATOM 7238 C CG . TYR B 1 537 ? -39.817 28.996 45.601 1.00 43.50 ? 510 TYR B CG 1 ATOM 7239 C CD1 . TYR B 1 537 ? -40.485 30.181 45.916 1.00 47.02 ? 510 TYR B CD1 1 ATOM 7240 C CD2 . TYR B 1 537 ? -39.102 28.348 46.609 1.00 44.85 ? 510 TYR B CD2 1 ATOM 7241 C CE1 . TYR B 1 537 ? -40.460 30.703 47.197 1.00 48.04 ? 510 TYR B CE1 1 ATOM 7242 C CE2 . TYR B 1 537 ? -39.065 28.865 47.895 1.00 47.59 ? 510 TYR B CE2 1 ATOM 7243 C CZ . TYR B 1 537 ? -39.747 30.042 48.177 1.00 50.36 ? 510 TYR B CZ 1 ATOM 7244 O OH . TYR B 1 537 ? -39.744 30.548 49.443 1.00 58.87 ? 510 TYR B OH 1 ATOM 7245 N N . TYR B 1 538 ? -39.953 25.382 44.311 1.00 33.40 ? 511 TYR B N 1 ATOM 7246 C CA . TYR B 1 538 ? -39.708 24.112 44.960 1.00 32.15 ? 511 TYR B CA 1 ATOM 7247 C C . TYR B 1 538 ? -38.243 24.046 45.359 1.00 34.69 ? 511 TYR B C 1 ATOM 7248 O O . TYR B 1 538 ? -37.347 24.120 44.504 1.00 33.60 ? 511 TYR B O 1 ATOM 7249 C CB . TYR B 1 538 ? -40.036 22.967 44.024 1.00 30.22 ? 511 TYR B CB 1 ATOM 7250 C CG . TYR B 1 538 ? -40.000 21.597 44.671 1.00 30.51 ? 511 TYR B CG 1 ATOM 7251 C CD1 . TYR B 1 538 ? -41.068 21.128 45.403 1.00 29.22 ? 511 TYR B CD1 1 ATOM 7252 C CD2 . TYR B 1 538 ? -38.886 20.766 44.530 1.00 31.06 ? 511 TYR B CD2 1 ATOM 7253 C CE1 . TYR B 1 538 ? -41.033 19.872 45.967 1.00 29.74 ? 511 TYR B CE1 1 ATOM 7254 C CE2 . TYR B 1 538 ? -38.842 19.504 45.091 1.00 31.11 ? 511 TYR B CE2 1 ATOM 7255 C CZ . TYR B 1 538 ? -39.919 19.064 45.815 1.00 30.93 ? 511 TYR B CZ 1 ATOM 7256 O OH . TYR B 1 538 ? -39.897 17.813 46.373 1.00 31.20 ? 511 TYR B OH 1 ATOM 7257 N N . ASN B 1 539 ? -38.024 23.925 46.661 1.00 36.96 ? 512 ASN B N 1 ATOM 7258 C CA . ASN B 1 539 ? -36.680 23.879 47.261 1.00 41.29 ? 512 ASN B CA 1 ATOM 7259 C C . ASN B 1 539 ? -36.335 22.427 47.487 1.00 40.75 ? 512 ASN B C 1 ATOM 7260 O O . ASN B 1 539 ? -36.874 21.754 48.395 1.00 41.04 ? 512 ASN B O 1 ATOM 7261 C CB . ASN B 1 539 ? -36.630 24.706 48.551 1.00 45.54 ? 512 ASN B CB 1 ATOM 7262 C CG . ASN B 1 539 ? -36.395 26.197 48.281 1.00 49.99 ? 512 ASN B CG 1 ATOM 7263 O OD1 . ASN B 1 539 ? -36.168 26.621 47.137 1.00 48.11 ? 512 ASN B OD1 1 ATOM 7264 N ND2 . ASN B 1 539 ? -36.446 26.997 49.338 1.00 56.61 ? 512 ASN B ND2 1 ATOM 7265 N N . VAL B 1 540 ? -35.479 21.925 46.602 1.00 39.15 ? 513 VAL B N 1 ATOM 7266 C CA . VAL B 1 540 ? -35.289 20.490 46.469 1.00 36.47 ? 513 VAL B CA 1 ATOM 7267 C C . VAL B 1 540 ? -34.728 19.836 47.724 1.00 37.27 ? 513 VAL B C 1 ATOM 7268 O O . VAL B 1 540 ? -35.217 18.775 48.158 1.00 39.35 ? 513 VAL B O 1 ATOM 7269 C CB . VAL B 1 540 ? -34.421 20.204 45.236 1.00 37.36 ? 513 VAL B CB 1 ATOM 7270 C CG1 . VAL B 1 540 ? -34.040 18.736 45.153 1.00 39.69 ? 513 VAL B CG1 1 ATOM 7271 C CG2 . VAL B 1 540 ? -35.180 20.614 43.986 1.00 35.70 ? 513 VAL B CG2 1 ATOM 7272 N N . TYR B 1 541 ? -33.737 20.461 48.340 1.00 41.31 ? 514 TYR B N 1 ATOM 7273 C CA . TYR B 1 541 ? -33.043 19.818 49.484 1.00 50.28 ? 514 TYR B CA 1 ATOM 7274 C C . TYR B 1 541 ? -33.501 20.320 50.869 1.00 58.37 ? 514 TYR B C 1 ATOM 7275 O O . TYR B 1 541 ? -32.667 20.508 51.758 1.00 65.46 ? 514 TYR B O 1 ATOM 7276 C CB . TYR B 1 541 ? -31.517 19.934 49.308 1.00 50.42 ? 514 TYR B CB 1 ATOM 7277 C CG . TYR B 1 541 ? -31.055 19.367 47.990 1.00 49.69 ? 514 TYR B CG 1 ATOM 7278 C CD1 . TYR B 1 541 ? -31.100 20.149 46.840 1.00 50.64 ? 514 TYR B CD1 1 ATOM 7279 C CD2 . TYR B 1 541 ? -30.628 18.043 47.875 1.00 50.42 ? 514 TYR B CD2 1 ATOM 7280 C CE1 . TYR B 1 541 ? -30.714 19.643 45.618 1.00 52.24 ? 514 TYR B CE1 1 ATOM 7281 C CE2 . TYR B 1 541 ? -30.234 17.522 46.648 1.00 50.39 ? 514 TYR B CE2 1 ATOM 7282 C CZ . TYR B 1 541 ? -30.276 18.336 45.524 1.00 51.82 ? 514 TYR B CZ 1 ATOM 7283 O OH . TYR B 1 541 ? -29.903 17.883 44.277 1.00 58.78 ? 514 TYR B OH 1 ATOM 7284 N N . ALA B 1 542 ? -34.807 20.583 51.019 1.00 56.13 ? 515 ALA B N 1 ATOM 7285 C CA . ALA B 1 542 ? -35.442 20.815 52.314 1.00 54.89 ? 515 ALA B CA 1 ATOM 7286 C C . ALA B 1 542 ? -36.172 19.564 52.801 1.00 59.93 ? 515 ALA B C 1 ATOM 7287 O O . ALA B 1 542 ? -36.445 18.626 52.021 1.00 59.97 ? 515 ALA B O 1 ATOM 7288 C CB . ALA B 1 542 ? -36.424 21.983 52.197 1.00 56.64 ? 515 ALA B CB 1 ATOM 7289 N N . LYS B 1 543 ? -36.541 19.568 54.084 1.00 64.66 ? 516 LYS B N 1 ATOM 7290 C CA . LYS B 1 543 ? -37.226 18.419 54.689 1.00 63.16 ? 516 LYS B CA 1 ATOM 7291 C C . LYS B 1 543 ? -38.663 18.334 54.197 1.00 65.38 ? 516 LYS B C 1 ATOM 7292 O O . LYS B 1 543 ? -39.242 19.348 53.791 1.00 67.79 ? 516 LYS B O 1 ATOM 7293 C CB . LYS B 1 543 ? -37.202 18.513 56.216 1.00 66.05 ? 516 LYS B CB 1 ATOM 7294 N N . LYS B 1 544 ? -39.215 17.118 54.206 1.00 66.31 ? 517 LYS B N 1 ATOM 7295 C CA . LYS B 1 544 ? -40.603 16.870 53.796 1.00 71.97 ? 517 LYS B CA 1 ATOM 7296 C C . LYS B 1 544 ? -41.521 17.933 54.394 1.00 73.95 ? 517 LYS B C 1 ATOM 7297 O O . LYS B 1 544 ? -41.345 18.342 55.542 1.00 75.75 ? 517 LYS B O 1 ATOM 7298 C CB . LYS B 1 544 ? -41.070 15.458 54.206 1.00 71.17 ? 517 LYS B CB 1 ATOM 7299 C CG . LYS B 1 544 ? -42.424 15.045 53.617 1.00 69.39 ? 517 LYS B CG 1 ATOM 7300 C CD . LYS B 1 544 ? -42.255 14.555 52.178 1.00 64.77 ? 517 LYS B CD 1 ATOM 7301 C CE . LYS B 1 544 ? -43.479 14.819 51.311 1.00 63.55 ? 517 LYS B CE 1 ATOM 7302 N NZ . LYS B 1 544 ? -44.594 13.872 51.586 1.00 63.54 ? 517 LYS B NZ 1 ATOM 7303 N N . GLY B 1 545 ? -42.465 18.420 53.590 1.00 74.33 ? 518 GLY B N 1 ATOM 7304 C CA . GLY B 1 545 ? -43.414 19.437 54.039 1.00 66.94 ? 518 GLY B CA 1 ATOM 7305 C C . GLY B 1 545 ? -42.856 20.845 54.183 1.00 64.31 ? 518 GLY B C 1 ATOM 7306 O O . GLY B 1 545 ? -43.596 21.739 54.579 1.00 65.06 ? 518 GLY B O 1 ATOM 7307 N N . GLU B 1 546 ? -41.577 21.059 53.854 1.00 58.08 ? 519 GLU B N 1 ATOM 7308 C CA . GLU B 1 546 ? -40.983 22.406 53.843 1.00 54.73 ? 519 GLU B CA 1 ATOM 7309 C C . GLU B 1 546 ? -40.313 22.731 52.490 1.00 48.21 ? 519 GLU B C 1 ATOM 7310 O O . GLU B 1 546 ? -39.473 23.614 52.396 1.00 48.96 ? 519 GLU B O 1 ATOM 7311 C CB . GLU B 1 546 ? -39.986 22.552 54.992 1.00 56.70 ? 519 GLU B CB 1 ATOM 7312 N N . ARG B 1 547 ? -40.722 22.034 51.435 1.00 48.81 ? 520 ARG B N 1 ATOM 7313 C CA . ARG B 1 547 ? -40.082 22.161 50.106 1.00 46.60 ? 520 ARG B CA 1 ATOM 7314 C C . ARG B 1 547 ? -40.863 23.027 49.135 1.00 40.02 ? 520 ARG B C 1 ATOM 7315 O O . ARG B 1 547 ? -40.310 23.759 48.340 1.00 37.31 ? 520 ARG B O 1 ATOM 7316 C CB . ARG B 1 547 ? -40.006 20.804 49.462 1.00 50.99 ? 520 ARG B CB 1 ATOM 7317 C CG . ARG B 1 547 ? -39.219 19.802 50.259 1.00 58.67 ? 520 ARG B CG 1 ATOM 7318 C CD . ARG B 1 547 ? -39.245 18.454 49.571 1.00 63.02 ? 520 ARG B CD 1 ATOM 7319 N NE . ARG B 1 547 ? -38.594 17.468 50.408 1.00 66.83 ? 520 ARG B NE 1 ATOM 7320 C CZ . ARG B 1 547 ? -38.903 16.178 50.433 1.00 68.50 ? 520 ARG B CZ 1 ATOM 7321 N NH1 . ARG B 1 547 ? -39.877 15.674 49.662 1.00 63.97 ? 520 ARG B NH1 1 ATOM 7322 N NH2 . ARG B 1 547 ? -38.230 15.390 51.257 1.00 72.01 ? 520 ARG B NH2 1 ATOM 7323 N N . LEU B 1 548 ? -42.169 22.948 49.241 1.00 39.18 ? 521 LEU B N 1 ATOM 7324 C CA . LEU B 1 548 ? -43.045 23.489 48.262 1.00 43.12 ? 521 LEU B CA 1 ATOM 7325 C C . LEU B 1 548 ? -43.542 24.822 48.794 1.00 43.61 ? 521 LEU B C 1 ATOM 7326 O O . LEU B 1 548 ? -44.008 24.895 49.912 1.00 42.38 ? 521 LEU B O 1 ATOM 7327 C CB . LEU B 1 548 ? -44.169 22.495 48.027 1.00 45.28 ? 521 LEU B CB 1 ATOM 7328 C CG . LEU B 1 548 ? -45.209 22.860 46.995 1.00 46.62 ? 521 LEU B CG 1 ATOM 7329 C CD1 . LEU B 1 548 ? -44.620 23.102 45.612 1.00 45.59 ? 521 LEU B CD1 1 ATOM 7330 C CD2 . LEU B 1 548 ? -46.223 21.732 46.943 1.00 48.94 ? 521 LEU B CD2 1 ATOM 7331 N N . PHE B 1 549 ? -43.361 25.880 48.010 1.00 43.55 ? 522 PHE B N 1 ATOM 7332 C CA . PHE B 1 549 ? -43.887 27.203 48.345 1.00 46.72 ? 522 PHE B CA 1 ATOM 7333 C C . PHE B 1 549 ? -44.754 27.635 47.177 1.00 48.43 ? 522 PHE B C 1 ATOM 7334 O O . PHE B 1 549 ? -44.279 27.734 46.053 1.00 51.46 ? 522 PHE B O 1 ATOM 7335 C CB . PHE B 1 549 ? -42.765 28.197 48.664 1.00 47.90 ? 522 PHE B CB 1 ATOM 7336 C CG . PHE B 1 549 ? -41.927 27.776 49.841 1.00 52.05 ? 522 PHE B CG 1 ATOM 7337 C CD1 . PHE B 1 549 ? -40.914 26.833 49.689 1.00 51.52 ? 522 PHE B CD1 1 ATOM 7338 C CD2 . PHE B 1 549 ? -42.186 28.275 51.116 1.00 52.67 ? 522 PHE B CD2 1 ATOM 7339 C CE1 . PHE B 1 549 ? -40.155 26.420 50.779 1.00 52.87 ? 522 PHE B CE1 1 ATOM 7340 C CE2 . PHE B 1 549 ? -41.432 27.866 52.203 1.00 52.89 ? 522 PHE B CE2 1 ATOM 7341 C CZ . PHE B 1 549 ? -40.415 26.938 52.035 1.00 52.27 ? 522 PHE B CZ 1 ATOM 7342 N N . ILE B 1 550 ? -46.053 27.759 47.428 1.00 45.97 ? 523 ILE B N 1 ATOM 7343 C CA . ILE B 1 550 ? -47.016 28.148 46.396 1.00 46.90 ? 523 ILE B CA 1 ATOM 7344 C C . ILE B 1 550 ? -47.845 29.321 46.895 1.00 44.11 ? 523 ILE B C 1 ATOM 7345 O O . ILE B 1 550 ? -48.342 29.281 48.008 1.00 42.86 ? 523 ILE B O 1 ATOM 7346 C CB . ILE B 1 550 ? -47.980 26.993 46.024 1.00 47.01 ? 523 ILE B CB 1 ATOM 7347 C CG1 . ILE B 1 550 ? -47.288 25.967 45.139 1.00 50.24 ? 523 ILE B CG1 1 ATOM 7348 C CG2 . ILE B 1 550 ? -49.205 27.519 45.279 1.00 48.69 ? 523 ILE B CG2 1 ATOM 7349 C CD1 . ILE B 1 550 ? -47.989 24.620 45.077 1.00 50.02 ? 523 ILE B CD1 1 ATOM 7350 N N . ASN B 1 551 ? -48.023 30.330 46.050 1.00 43.80 ? 524 ASN B N 1 ATOM 7351 C CA . ASN B 1 551 ? -49.029 31.373 46.289 1.00 44.63 ? 524 ASN B CA 1 ATOM 7352 C C . ASN B 1 551 ? -50.346 31.054 45.557 1.00 41.20 ? 524 ASN B C 1 ATOM 7353 O O . ASN B 1 551 ? -50.537 31.424 44.409 1.00 34.72 ? 524 ASN B O 1 ATOM 7354 C CB . ASN B 1 551 ? -48.492 32.729 45.866 1.00 49.33 ? 524 ASN B CB 1 ATOM 7355 C CG . ASN B 1 551 ? -47.159 33.055 46.521 1.00 55.56 ? 524 ASN B CG 1 ATOM 7356 O OD1 . ASN B 1 551 ? -46.968 32.845 47.724 1.00 59.28 ? 524 ASN B OD1 1 ATOM 7357 N ND2 . ASN B 1 551 ? -46.219 33.550 45.727 1.00 58.23 ? 524 ASN B ND2 1 ATOM 7358 N N . GLU B 1 552 ? -51.235 30.338 46.241 1.00 43.95 ? 525 GLU B N 1 ATOM 7359 C CA . GLU B 1 552 ? -52.517 29.860 45.674 1.00 44.26 ? 525 GLU B CA 1 ATOM 7360 C C . GLU B 1 552 ? -53.340 30.986 45.047 1.00 41.17 ? 525 GLU B C 1 ATOM 7361 O O . GLU B 1 552 ? -54.004 30.783 44.034 1.00 39.56 ? 525 GLU B O 1 ATOM 7362 C CB . GLU B 1 552 ? -53.401 29.172 46.732 1.00 49.19 ? 525 GLU B CB 1 ATOM 7363 C CG . GLU B 1 552 ? -52.768 28.028 47.502 1.00 54.85 ? 525 GLU B CG 1 ATOM 7364 C CD . GLU B 1 552 ? -51.676 28.477 48.439 1.00 58.72 ? 525 GLU B CD 1 ATOM 7365 O OE1 . GLU B 1 552 ? -51.596 29.672 48.778 1.00 68.12 ? 525 GLU B OE1 1 ATOM 7366 O OE2 . GLU B 1 552 ? -50.869 27.635 48.832 1.00 67.77 ? 525 GLU B OE2 1 ATOM 7367 N N . GLU B 1 553 ? -53.323 32.159 45.678 1.00 40.75 ? 526 GLU B N 1 ATOM 7368 C CA . GLU B 1 553 ? -54.110 33.298 45.204 1.00 43.42 ? 526 GLU B CA 1 ATOM 7369 C C . GLU B 1 553 ? -53.729 33.696 43.779 1.00 40.72 ? 526 GLU B C 1 ATOM 7370 O O . GLU B 1 553 ? -54.537 34.265 43.055 1.00 39.41 ? 526 GLU B O 1 ATOM 7371 C CB . GLU B 1 553 ? -53.992 34.505 46.158 1.00 44.82 ? 526 GLU B CB 1 ATOM 7372 C CG . GLU B 1 553 ? -52.640 35.207 46.170 1.00 48.76 ? 526 GLU B CG 1 ATOM 7373 C CD . GLU B 1 553 ? -51.612 34.540 47.070 1.00 54.71 ? 526 GLU B CD 1 ATOM 7374 O OE1 . GLU B 1 553 ? -51.907 33.498 47.691 1.00 58.93 ? 526 GLU B OE1 1 ATOM 7375 O OE2 . GLU B 1 553 ? -50.489 35.068 47.159 1.00 59.82 ? 526 GLU B OE2 1 ATOM 7376 N N . LYS B 1 554 ? -52.494 33.411 43.377 1.00 38.43 ? 527 LYS B N 1 ATOM 7377 C CA . LYS B 1 554 ? -52.041 33.781 42.044 1.00 38.19 ? 527 LYS B CA 1 ATOM 7378 C C . LYS B 1 554 ? -52.449 32.793 40.951 1.00 35.62 ? 527 LYS B C 1 ATOM 7379 O O . LYS B 1 554 ? -52.235 33.074 39.783 1.00 34.48 ? 527 LYS B O 1 ATOM 7380 C CB . LYS B 1 554 ? -50.523 33.966 42.051 1.00 40.40 ? 527 LYS B CB 1 ATOM 7381 C CG . LYS B 1 554 ? -50.069 35.116 42.925 1.00 44.76 ? 527 LYS B CG 1 ATOM 7382 C CD . LYS B 1 554 ? -48.555 35.178 42.999 1.00 51.47 ? 527 LYS B CD 1 ATOM 7383 C CE . LYS B 1 554 ? -48.072 36.581 43.274 1.00 55.75 ? 527 LYS B CE 1 ATOM 7384 N NZ . LYS B 1 554 ? -46.664 36.549 43.758 1.00 64.92 ? 527 LYS B NZ 1 ATOM 7385 N N . ILE B 1 555 ? -52.996 31.637 41.322 1.00 33.54 ? 528 ILE B N 1 ATOM 7386 C CA . ILE B 1 555 ? -53.296 30.588 40.356 1.00 35.61 ? 528 ILE B CA 1 ATOM 7387 C C . ILE B 1 555 ? -54.639 30.839 39.680 1.00 35.11 ? 528 ILE B C 1 ATOM 7388 O O . ILE B 1 555 ? -55.627 31.095 40.354 1.00 37.60 ? 528 ILE B O 1 ATOM 7389 C CB . ILE B 1 555 ? -53.279 29.173 41.013 1.00 35.40 ? 528 ILE B CB 1 ATOM 7390 C CG1 . ILE B 1 555 ? -51.869 28.803 41.465 1.00 38.35 ? 528 ILE B CG1 1 ATOM 7391 C CG2 . ILE B 1 555 ? -53.758 28.098 40.052 1.00 37.81 ? 528 ILE B CG2 1 ATOM 7392 C CD1 . ILE B 1 555 ? -51.831 27.672 42.476 1.00 40.00 ? 528 ILE B CD1 1 ATOM 7393 N N . LEU B 1 556 ? -54.650 30.800 38.357 1.00 36.38 ? 529 LEU B N 1 ATOM 7394 C CA . LEU B 1 556 ? -55.861 30.589 37.546 1.00 41.64 ? 529 LEU B CA 1 ATOM 7395 C C . LEU B 1 556 ? -56.008 29.139 37.142 1.00 45.04 ? 529 LEU B C 1 ATOM 7396 O O . LEU B 1 556 ? -55.162 28.606 36.420 1.00 48.93 ? 529 LEU B O 1 ATOM 7397 C CB . LEU B 1 556 ? -55.810 31.373 36.227 1.00 45.65 ? 529 LEU B CB 1 ATOM 7398 N N . TRP B 1 557 ? -57.099 28.513 37.572 1.00 44.66 ? 530 TRP B N 1 ATOM 7399 C CA . TRP B 1 557 ? -57.351 27.112 37.247 1.00 48.76 ? 530 TRP B CA 1 ATOM 7400 C C . TRP B 1 557 ? -57.847 26.896 35.813 1.00 53.11 ? 530 TRP B C 1 ATOM 7401 O O . TRP B 1 557 ? -57.770 25.779 35.309 1.00 55.02 ? 530 TRP B O 1 ATOM 7402 C CB . TRP B 1 557 ? -58.279 26.499 38.283 1.00 46.23 ? 530 TRP B CB 1 ATOM 7403 C CG . TRP B 1 557 ? -57.662 26.559 39.625 1.00 48.23 ? 530 TRP B CG 1 ATOM 7404 C CD1 . TRP B 1 557 ? -57.928 27.465 40.613 1.00 49.27 ? 530 TRP B CD1 1 ATOM 7405 C CD2 . TRP B 1 557 ? -56.609 25.728 40.118 1.00 47.79 ? 530 TRP B CD2 1 ATOM 7406 N NE1 . TRP B 1 557 ? -57.133 27.226 41.703 1.00 47.13 ? 530 TRP B NE1 1 ATOM 7407 C CE2 . TRP B 1 557 ? -56.317 26.161 41.431 1.00 46.95 ? 530 TRP B CE2 1 ATOM 7408 C CE3 . TRP B 1 557 ? -55.894 24.646 39.585 1.00 45.08 ? 530 TRP B CE3 1 ATOM 7409 C CZ2 . TRP B 1 557 ? -55.339 25.551 42.220 1.00 45.72 ? 530 TRP B CZ2 1 ATOM 7410 C CZ3 . TRP B 1 557 ? -54.924 24.045 40.370 1.00 44.67 ? 530 TRP B CZ3 1 ATOM 7411 C CH2 . TRP B 1 557 ? -54.656 24.494 41.668 1.00 44.39 ? 530 TRP B CH2 1 ATOM 7412 N N . SER B 1 558 ? -58.371 27.953 35.181 1.00 62.09 ? 531 SER B N 1 ATOM 7413 C CA . SER B 1 558 ? -58.362 28.099 33.705 1.00 66.75 ? 531 SER B CA 1 ATOM 7414 C C . SER B 1 558 ? -57.392 29.235 33.316 1.00 69.53 ? 531 SER B C 1 ATOM 7415 O O . SER B 1 558 ? -57.324 29.659 32.159 1.00 71.41 ? 531 SER B O 1 ATOM 7416 C CB . SER B 1 558 ? -59.765 28.377 33.151 1.00 69.96 ? 531 SER B CB 1 ATOM 7417 O OG . SER B 1 558 ? -60.018 29.766 32.980 1.00 69.54 ? 531 SER B OG 1 HETATM 7418 N N . TCR C 2 . ? -32.694 -10.306 25.146 1.00 32.04 ? 601 TCR A N 1 HETATM 7419 C CA . TCR C 2 . ? -31.721 -9.739 26.113 1.00 31.53 ? 601 TCR A CA 1 HETATM 7420 C CB . TCR C 2 . ? -30.340 -10.393 26.063 1.00 31.34 ? 601 TCR A CB 1 HETATM 7421 C CG . TCR C 2 . ? -30.523 -11.873 26.055 1.00 33.78 ? 601 TCR A CG 1 HETATM 7422 C CD2 . TCR C 2 . ? -29.642 -12.995 26.459 1.00 36.00 ? 601 TCR A CD2 1 HETATM 7423 C CE2 . TCR C 2 . ? -30.432 -14.225 26.224 1.00 37.31 ? 601 TCR A CE2 1 HETATM 7424 C CE3 . TCR C 2 . ? -28.340 -13.051 26.939 1.00 37.40 ? 601 TCR A CE3 1 HETATM 7425 C CD1 . TCR C 2 . ? -31.759 -12.526 25.642 1.00 33.96 ? 601 TCR A CD1 1 HETATM 7426 N NE1 . TCR C 2 . ? -31.645 -13.869 25.753 1.00 35.72 ? 601 TCR A NE1 1 HETATM 7427 C CZ2 . TCR C 2 . ? -29.839 -15.449 26.505 1.00 38.75 ? 601 TCR A CZ2 1 HETATM 7428 C CZ3 . TCR C 2 . ? -27.796 -14.307 27.200 1.00 40.92 ? 601 TCR A CZ3 1 HETATM 7429 C CH2 . TCR C 2 . ? -28.532 -15.483 26.980 1.00 39.20 ? 601 TCR A CH2 1 HETATM 7430 C C9 . TCR C 2 . ? -32.957 -11.750 25.212 1.00 34.67 ? 601 TCR A C9 1 HETATM 7431 C C . TCR C 2 . ? -31.586 -8.289 25.754 1.00 29.23 ? 601 TCR A C 1 HETATM 7432 O OXT . TCR C 2 . ? -30.771 -7.553 26.372 1.00 25.48 ? 601 TCR A OXT 1 HETATM 7433 O O1 . TCR C 2 . ? -32.339 -7.872 24.846 1.00 28.25 ? 601 TCR A O1 1 HETATM 7434 C C1 . NAG D 3 . ? -46.641 -21.398 17.446 1.00 62.35 ? 602 NAG A C1 1 HETATM 7435 C C2 . NAG D 3 . ? -46.121 -21.791 16.058 1.00 66.77 ? 602 NAG A C2 1 HETATM 7436 C C3 . NAG D 3 . ? -47.258 -21.960 15.059 1.00 71.24 ? 602 NAG A C3 1 HETATM 7437 C C4 . NAG D 3 . ? -48.380 -22.872 15.546 1.00 73.69 ? 602 NAG A C4 1 HETATM 7438 C C5 . NAG D 3 . ? -48.484 -23.042 17.075 1.00 70.96 ? 602 NAG A C5 1 HETATM 7439 C C6 . NAG D 3 . ? -48.489 -24.534 17.397 1.00 66.37 ? 602 NAG A C6 1 HETATM 7440 C C7 . NAG D 3 . ? -43.870 -21.008 15.441 1.00 66.85 ? 602 NAG A C7 1 HETATM 7441 C C8 . NAG D 3 . ? -43.033 -19.926 14.803 1.00 66.08 ? 602 NAG A C8 1 HETATM 7442 N N2 . NAG D 3 . ? -45.189 -20.821 15.489 1.00 65.88 ? 602 NAG A N2 1 HETATM 7443 O O3 . NAG D 3 . ? -46.732 -22.512 13.873 1.00 71.26 ? 602 NAG A O3 1 HETATM 7444 O O4 . NAG D 3 . ? -49.608 -22.376 15.028 1.00 76.07 ? 602 NAG A O4 1 HETATM 7445 O O5 . NAG D 3 . ? -47.487 -22.432 17.909 1.00 68.95 ? 602 NAG A O5 1 HETATM 7446 O O6 . NAG D 3 . ? -48.646 -24.702 18.788 1.00 65.14 ? 602 NAG A O6 1 HETATM 7447 O O7 . NAG D 3 . ? -43.341 -22.017 15.900 1.00 72.00 ? 602 NAG A O7 1 HETATM 7448 C C1 . NAG E 3 . ? -43.578 -16.016 2.295 1.00 79.23 ? 603 NAG A C1 1 HETATM 7449 C C2 . NAG E 3 . ? -44.861 -15.213 2.571 1.00 82.40 ? 603 NAG A C2 1 HETATM 7450 C C3 . NAG E 3 . ? -46.134 -16.059 2.487 1.00 81.66 ? 603 NAG A C3 1 HETATM 7451 C C4 . NAG E 3 . ? -46.136 -16.838 1.191 1.00 80.60 ? 603 NAG A C4 1 HETATM 7452 C C5 . NAG E 3 . ? -44.912 -17.739 1.205 1.00 84.53 ? 603 NAG A C5 1 HETATM 7453 C C6 . NAG E 3 . ? -44.944 -18.668 -0.003 1.00 82.72 ? 603 NAG A C6 1 HETATM 7454 C C7 . NAG E 3 . ? -44.983 -13.258 4.051 1.00 84.96 ? 603 NAG A C7 1 HETATM 7455 C C8 . NAG E 3 . ? -44.921 -12.730 5.457 1.00 79.92 ? 603 NAG A C8 1 HETATM 7456 N N2 . NAG E 3 . ? -44.813 -14.574 3.881 1.00 86.09 ? 603 NAG A N2 1 HETATM 7457 O O3 . NAG E 3 . ? -47.293 -15.259 2.546 1.00 79.46 ? 603 NAG A O3 1 HETATM 7458 O O4 . NAG E 3 . ? -47.319 -17.591 1.098 1.00 82.13 ? 603 NAG A O4 1 HETATM 7459 O O5 . NAG E 3 . ? -43.740 -16.931 1.212 1.00 83.62 ? 603 NAG A O5 1 HETATM 7460 O O6 . NAG E 3 . ? -43.632 -18.985 -0.396 1.00 87.34 ? 603 NAG A O6 1 HETATM 7461 O O7 . NAG E 3 . ? -45.173 -12.480 3.116 1.00 87.88 ? 603 NAG A O7 1 HETATM 7462 C C1 . NAG F 3 . ? -32.053 -21.581 55.672 1.00 88.22 ? 604 NAG A C1 1 HETATM 7463 C C2 . NAG F 3 . ? -31.461 -22.733 56.467 1.00 88.64 ? 604 NAG A C2 1 HETATM 7464 C C3 . NAG F 3 . ? -31.802 -24.004 55.689 1.00 91.57 ? 604 NAG A C3 1 HETATM 7465 C C4 . NAG F 3 . ? -33.148 -23.934 54.930 1.00 92.14 ? 604 NAG A C4 1 HETATM 7466 C C5 . NAG F 3 . ? -34.094 -22.775 55.320 1.00 91.51 ? 604 NAG A C5 1 HETATM 7467 C C6 . NAG F 3 . ? -35.222 -23.206 56.260 1.00 90.54 ? 604 NAG A C6 1 HETATM 7468 C C7 . NAG F 3 . ? -29.474 -21.682 57.479 1.00 79.83 ? 604 NAG A C7 1 HETATM 7469 C C8 . NAG F 3 . ? -27.975 -21.665 57.592 1.00 77.98 ? 604 NAG A C8 1 HETATM 7470 N N2 . NAG F 3 . ? -30.020 -22.598 56.668 1.00 82.97 ? 604 NAG A N2 1 HETATM 7471 O O3 . NAG F 3 . ? -31.793 -25.097 56.577 1.00 92.17 ? 604 NAG A O3 1 HETATM 7472 O O4 . NAG F 3 . ? -32.905 -23.845 53.535 1.00 86.56 ? 604 NAG A O4 1 HETATM 7473 O O5 . NAG F 3 . ? -33.452 -21.637 55.879 1.00 88.95 ? 604 NAG A O5 1 HETATM 7474 O O6 . NAG F 3 . ? -36.358 -22.409 56.000 1.00 86.77 ? 604 NAG A O6 1 HETATM 7475 O O7 . NAG F 3 . ? -30.125 -20.869 58.132 1.00 75.63 ? 604 NAG A O7 1 HETATM 7476 C C1 . NAG G 3 . ? -36.453 -3.267 56.044 1.00 71.24 ? 605 NAG A C1 1 HETATM 7477 C C2 . NAG G 3 . ? -36.047 -1.804 55.898 1.00 74.78 ? 605 NAG A C2 1 HETATM 7478 C C3 . NAG G 3 . ? -35.121 -1.398 57.039 1.00 77.41 ? 605 NAG A C3 1 HETATM 7479 C C4 . NAG G 3 . ? -35.856 -1.521 58.362 1.00 81.06 ? 605 NAG A C4 1 HETATM 7480 C C5 . NAG G 3 . ? -36.703 -2.808 58.418 1.00 84.91 ? 605 NAG A C5 1 HETATM 7481 C C6 . NAG G 3 . ? -38.199 -2.508 58.359 1.00 86.43 ? 605 NAG A C6 1 HETATM 7482 C C7 . NAG G 3 . ? -36.085 -1.294 53.516 1.00 65.16 ? 605 NAG A C7 1 HETATM 7483 C C8 . NAG G 3 . ? -35.312 -1.093 52.249 1.00 67.08 ? 605 NAG A C8 1 HETATM 7484 N N2 . NAG G 3 . ? -35.404 -1.592 54.611 1.00 71.98 ? 605 NAG A N2 1 HETATM 7485 O O3 . NAG G 3 . ? -34.674 -0.074 56.889 1.00 75.27 ? 605 NAG A O3 1 HETATM 7486 O O4 . NAG G 3 . ? -34.877 -1.492 59.375 1.00 78.90 ? 605 NAG A O4 1 HETATM 7487 O O5 . NAG G 3 . ? -36.393 -3.739 57.385 1.00 81.54 ? 605 NAG A O5 1 HETATM 7488 O O6 . NAG G 3 . ? -38.610 -2.078 59.632 1.00 86.85 ? 605 NAG A O6 1 HETATM 7489 O O7 . NAG G 3 . ? -37.297 -1.184 53.513 1.00 62.74 ? 605 NAG A O7 1 HETATM 7490 CL CL . CL H 4 . ? -22.650 -8.635 22.260 1.00 42.11 ? 606 CL A CL 1 HETATM 7491 CL CL . CL I 4 . ? -30.616 1.214 12.883 1.00 51.21 ? 607 CL A CL 1 HETATM 7492 CL CL . CL J 4 . ? -25.868 -15.822 31.022 1.00 57.79 ? 608 CL A CL 1 HETATM 7493 C C . BCT K 5 . ? -28.021 -21.109 22.978 1.00 36.01 ? 609 BCT A C 1 HETATM 7494 O O1 . BCT K 5 . ? -27.960 -21.690 21.794 1.00 34.35 ? 609 BCT A O1 1 HETATM 7495 O O2 . BCT K 5 . ? -26.963 -20.965 23.602 1.00 36.05 ? 609 BCT A O2 1 HETATM 7496 O O3 . BCT K 5 . ? -29.119 -20.684 23.417 1.00 40.91 ? 609 BCT A O3 1 HETATM 7497 MG MG . MG L 6 . ? -21.550 -19.733 -1.808 1.00 56.91 ? 610 MG A MG 1 HETATM 7498 N N . TCR M 2 . ? -34.884 17.993 29.647 1.00 30.90 ? 601 TCR B N 1 HETATM 7499 C CA . TCR M 2 . ? -35.503 17.418 28.424 1.00 28.43 ? 601 TCR B CA 1 HETATM 7500 C CB . TCR M 2 . ? -35.410 18.258 27.161 1.00 31.11 ? 601 TCR B CB 1 HETATM 7501 C CG . TCR M 2 . ? -35.745 19.666 27.499 1.00 34.30 ? 601 TCR B CG 1 HETATM 7502 C CD2 . TCR M 2 . ? -36.217 20.779 26.680 1.00 36.56 ? 601 TCR B CD2 1 HETATM 7503 C CE2 . TCR M 2 . ? -36.375 21.923 27.610 1.00 40.08 ? 601 TCR B CE2 1 HETATM 7504 C CE3 . TCR M 2 . ? -36.459 20.905 25.332 1.00 42.75 ? 601 TCR B CE3 1 HETATM 7505 C CD1 . TCR M 2 . ? -35.691 20.211 28.853 1.00 37.58 ? 601 TCR B CD1 1 HETATM 7506 N NE1 . TCR M 2 . ? -36.058 21.517 28.844 1.00 37.72 ? 601 TCR B NE1 1 HETATM 7507 C CZ2 . TCR M 2 . ? -36.807 23.149 27.102 1.00 43.27 ? 601 TCR B CZ2 1 HETATM 7508 C CZ3 . TCR M 2 . ? -36.875 22.163 24.858 1.00 46.03 ? 601 TCR B CZ3 1 HETATM 7509 C CH2 . TCR M 2 . ? -37.058 23.262 25.730 1.00 43.58 ? 601 TCR B CH2 1 HETATM 7510 C C9 . TCR M 2 . ? -35.299 19.359 30.040 1.00 35.61 ? 601 TCR B C9 1 HETATM 7511 C C . TCR M 2 . ? -34.762 16.148 28.136 1.00 26.20 ? 601 TCR B C 1 HETATM 7512 O OXT . TCR M 2 . ? -33.868 15.826 28.961 1.00 24.03 ? 601 TCR B OXT 1 HETATM 7513 O O1 . TCR M 2 . ? -35.053 15.494 27.092 1.00 23.41 ? 601 TCR B O1 1 HETATM 7514 C C1 . NAG N 3 . ? -32.636 26.343 46.881 1.00 55.70 ? 602 NAG B C1 1 HETATM 7515 C C2 . NAG N 3 . ? -31.180 26.071 47.215 1.00 57.29 ? 602 NAG B C2 1 HETATM 7516 C C3 . NAG N 3 . ? -30.946 26.078 48.728 1.00 61.75 ? 602 NAG B C3 1 HETATM 7517 C C4 . NAG N 3 . ? -31.509 27.341 49.365 1.00 65.53 ? 602 NAG B C4 1 HETATM 7518 C C5 . NAG N 3 . ? -32.971 27.481 48.944 1.00 64.54 ? 602 NAG B C5 1 HETATM 7519 C C6 . NAG N 3 . ? -33.599 28.750 49.505 1.00 64.89 ? 602 NAG B C6 1 HETATM 7520 C C7 . NAG N 3 . ? -30.091 24.596 45.611 1.00 56.15 ? 602 NAG B C7 1 HETATM 7521 C C8 . NAG N 3 . ? -29.767 23.168 45.277 1.00 59.23 ? 602 NAG B C8 1 HETATM 7522 N N2 . NAG N 3 . ? -30.792 24.766 46.728 1.00 54.18 ? 602 NAG B N2 1 HETATM 7523 O O3 . NAG N 3 . ? -29.570 25.960 49.003 1.00 63.54 ? 602 NAG B O3 1 HETATM 7524 O O4 . NAG N 3 . ? -31.385 27.262 50.771 1.00 67.93 ? 602 NAG B O4 1 HETATM 7525 O O5 . NAG N 3 . ? -33.003 27.552 47.530 1.00 60.89 ? 602 NAG B O5 1 HETATM 7526 O O6 . NAG N 3 . ? -32.986 29.867 48.903 1.00 61.91 ? 602 NAG B O6 1 HETATM 7527 O O7 . NAG N 3 . ? -29.734 25.513 44.870 1.00 47.90 ? 602 NAG B O7 1 HETATM 7528 C C1 . NAG O 3 . ? -16.478 25.646 46.756 1.00 47.03 ? 603 NAG B C1 1 HETATM 7529 C C2 . NAG O 3 . ? -16.647 24.775 47.991 1.00 47.25 ? 603 NAG B C2 1 HETATM 7530 C C3 . NAG O 3 . ? -17.179 25.603 49.162 1.00 47.78 ? 603 NAG B C3 1 HETATM 7531 C C4 . NAG O 3 . ? -16.301 26.793 49.379 1.00 48.93 ? 603 NAG B C4 1 HETATM 7532 C C5 . NAG O 3 . ? -16.289 27.624 48.112 1.00 49.94 ? 603 NAG B C5 1 HETATM 7533 C C6 . NAG O 3 . ? -15.432 28.865 48.307 1.00 50.61 ? 603 NAG B C6 1 HETATM 7534 C C7 . NAG O 3 . ? -17.202 22.465 47.361 1.00 48.33 ? 603 NAG B C7 1 HETATM 7535 C C8 . NAG O 3 . ? -18.305 21.480 47.115 1.00 49.48 ? 603 NAG B C8 1 HETATM 7536 N N2 . NAG O 3 . ? -17.564 23.695 47.706 1.00 46.84 ? 603 NAG B N2 1 HETATM 7537 O O3 . NAG O 3 . ? -17.139 24.897 50.371 1.00 49.31 ? 603 NAG B O3 1 HETATM 7538 O O4 . NAG O 3 . ? -16.847 27.521 50.442 1.00 54.85 ? 603 NAG B O4 1 HETATM 7539 O O5 . NAG O 3 . ? -15.745 26.829 47.083 1.00 48.45 ? 603 NAG B O5 1 HETATM 7540 O O6 . NAG O 3 . ? -14.202 28.480 48.896 1.00 54.74 ? 603 NAG B O6 1 HETATM 7541 O O7 . NAG O 3 . ? -16.040 22.099 47.219 1.00 51.87 ? 603 NAG B O7 1 HETATM 7542 C C1 . NAG P 3 . ? -66.047 23.953 23.666 1.00 96.74 ? 604 NAG B C1 1 HETATM 7543 C C2 . NAG P 3 . ? -66.139 25.017 22.544 1.00 104.03 ? 604 NAG B C2 1 HETATM 7544 C C3 . NAG P 3 . ? -67.580 25.453 22.274 1.00 104.09 ? 604 NAG B C3 1 HETATM 7545 C C4 . NAG P 3 . ? -68.365 25.745 23.569 1.00 104.20 ? 604 NAG B C4 1 HETATM 7546 C C5 . NAG P 3 . ? -67.633 25.231 24.815 1.00 103.92 ? 604 NAG B C5 1 HETATM 7547 C C6 . NAG P 3 . ? -68.491 25.234 26.076 1.00 97.51 ? 604 NAG B C6 1 HETATM 7548 C C7 . NAG P 3 . ? -64.731 26.953 21.875 1.00 101.87 ? 604 NAG B C7 1 HETATM 7549 C C8 . NAG P 3 . ? -63.863 28.097 22.331 1.00 96.87 ? 604 NAG B C8 1 HETATM 7550 N N2 . NAG P 3 . ? -65.278 26.176 22.822 1.00 106.43 ? 604 NAG B N2 1 HETATM 7551 O O3 . NAG P 3 . ? -68.185 24.430 21.507 1.00 101.68 ? 604 NAG B O3 1 HETATM 7552 O O4 . NAG P 3 . ? -68.568 27.134 23.702 1.00 102.20 ? 604 NAG B O4 1 HETATM 7553 O O5 . NAG P 3 . ? -67.171 23.922 24.527 1.00 99.98 ? 604 NAG B O5 1 HETATM 7554 O O6 . NAG P 3 . ? -67.709 24.715 27.129 1.00 91.98 ? 604 NAG B O6 1 HETATM 7555 O O7 . NAG P 3 . ? -64.904 26.775 20.671 1.00 101.59 ? 604 NAG B O7 1 HETATM 7556 C C1 . NAG Q 3 . ? -63.982 4.793 25.485 1.00 81.01 ? 605 NAG B C1 1 HETATM 7557 C C2 . NAG Q 3 . ? -63.461 3.434 24.960 1.00 85.69 ? 605 NAG B C2 1 HETATM 7558 C C3 . NAG Q 3 . ? -64.277 2.770 23.839 1.00 90.67 ? 605 NAG B C3 1 HETATM 7559 C C4 . NAG Q 3 . ? -65.750 3.128 23.933 1.00 96.82 ? 605 NAG B C4 1 HETATM 7560 C C5 . NAG Q 3 . ? -65.812 4.652 23.982 1.00 98.04 ? 605 NAG B C5 1 HETATM 7561 C C6 . NAG Q 3 . ? -67.205 5.215 23.706 1.00 100.56 ? 605 NAG B C6 1 HETATM 7562 C C7 . NAG Q 3 . ? -61.040 3.385 25.344 1.00 77.73 ? 605 NAG B C7 1 HETATM 7563 C C8 . NAG Q 3 . ? -59.654 3.458 24.759 1.00 74.58 ? 605 NAG B C8 1 HETATM 7564 N N2 . NAG Q 3 . ? -62.073 3.506 24.506 1.00 82.24 ? 605 NAG B N2 1 HETATM 7565 O O3 . NAG Q 3 . ? -64.134 1.370 23.906 1.00 89.35 ? 605 NAG B O3 1 HETATM 7566 O O4 . NAG Q 3 . ? -66.466 2.572 22.853 1.00 92.78 ? 605 NAG B O4 1 HETATM 7567 O O5 . NAG Q 3 . ? -65.371 4.996 25.283 1.00 86.84 ? 605 NAG B O5 1 HETATM 7568 O O6 . NAG Q 3 . ? -68.112 4.715 24.665 1.00 107.81 ? 605 NAG B O6 1 HETATM 7569 O O7 . NAG Q 3 . ? -61.185 3.225 26.553 1.00 74.13 ? 605 NAG B O7 1 HETATM 7570 CL CL . CL R 4 . ? -29.954 19.418 20.652 1.00 43.01 ? 606 CL B CL 1 HETATM 7571 CL CL . CL S 4 . ? -19.948 10.075 28.544 1.00 49.65 ? 607 CL B CL 1 HETATM 7572 CL CL . CL T 4 . ? -40.522 23.402 22.631 1.00 58.63 ? 608 CL B CL 1 HETATM 7573 C C . BCT U 5 . ? -34.657 29.757 27.749 1.00 33.63 ? 609 BCT B C 1 HETATM 7574 O O1 . BCT U 5 . ? -35.039 29.721 26.540 1.00 38.46 ? 609 BCT B O1 1 HETATM 7575 O O2 . BCT U 5 . ? -35.120 29.003 28.632 1.00 35.63 ? 609 BCT B O2 1 HETATM 7576 O O3 . BCT U 5 . ? -33.731 30.615 28.085 1.00 28.08 ? 609 BCT B O3 1 HETATM 7577 MG MG . MG V 6 . ? -49.775 2.672 31.119 1.00 45.02 ? 610 MG B MG 1 HETATM 7578 MG MG . MG W 6 . ? -9.904 35.664 27.491 1.00 57.45 ? 611 MG B MG 1 HETATM 7579 O O . HOH X 7 . ? -11.893 -9.282 24.038 1.00 45.98 ? 701 HOH A O 1 HETATM 7580 O O . HOH X 7 . ? -46.911 -4.824 21.467 1.00 50.38 ? 702 HOH A O 1 HETATM 7581 O O . HOH X 7 . ? -46.087 -0.966 27.844 1.00 44.26 ? 703 HOH A O 1 HETATM 7582 O O . HOH X 7 . ? -33.702 -0.464 42.902 1.00 39.80 ? 704 HOH A O 1 HETATM 7583 O O . HOH X 7 . ? -21.923 -5.428 41.209 1.00 40.16 ? 705 HOH A O 1 HETATM 7584 O O . HOH X 7 . ? -35.726 -25.167 46.797 1.00 49.48 ? 706 HOH A O 1 HETATM 7585 O O . HOH X 7 . ? -36.461 -11.967 27.162 1.00 36.30 ? 707 HOH A O 1 HETATM 7586 O O . HOH X 7 . ? -40.274 -4.091 50.939 1.00 41.80 ? 708 HOH A O 1 HETATM 7587 O O . HOH X 7 . ? -29.424 -7.476 28.575 1.00 31.79 ? 709 HOH A O 1 HETATM 7588 O O . HOH X 7 . ? -40.564 -16.473 51.303 1.00 56.65 ? 710 HOH A O 1 HETATM 7589 O O . HOH X 7 . ? -48.339 2.524 35.092 1.00 44.07 ? 711 HOH A O 1 HETATM 7590 O O . HOH X 7 . ? -54.235 -16.193 32.402 1.00 36.49 ? 712 HOH A O 1 HETATM 7591 O O . HOH X 7 . ? -38.490 -9.573 16.806 1.00 36.21 ? 713 HOH A O 1 HETATM 7592 O O . HOH X 7 . ? -49.681 -12.090 24.550 1.00 36.30 ? 714 HOH A O 1 HETATM 7593 O O . HOH X 7 . ? -0.614 12.582 34.183 1.00 55.06 ? 715 HOH A O 1 HETATM 7594 O O . HOH X 7 . ? -23.156 -17.263 39.983 1.00 40.70 ? 716 HOH A O 1 HETATM 7595 O O . HOH X 7 . ? -31.194 4.446 12.743 1.00 31.04 ? 717 HOH A O 1 HETATM 7596 O O . HOH X 7 . ? -34.773 -17.883 15.229 1.00 54.08 ? 718 HOH A O 1 HETATM 7597 O O . HOH X 7 . ? -53.664 -15.149 45.695 1.00 50.96 ? 719 HOH A O 1 HETATM 7598 O O . HOH X 7 . ? -42.163 -1.389 27.303 1.00 28.68 ? 720 HOH A O 1 HETATM 7599 O O . HOH X 7 . ? -41.876 -5.214 26.100 1.00 31.85 ? 721 HOH A O 1 HETATM 7600 O O . HOH X 7 . ? -34.293 -19.210 28.618 1.00 34.76 ? 722 HOH A O 1 HETATM 7601 O O . HOH X 7 . ? -27.653 1.645 25.771 1.00 48.69 ? 723 HOH A O 1 HETATM 7602 O O . HOH X 7 . ? -44.114 -14.063 51.319 1.00 66.98 ? 724 HOH A O 1 HETATM 7603 O O . HOH X 7 . ? -9.686 -6.916 27.913 1.00 54.11 ? 725 HOH A O 1 HETATM 7604 O O . HOH X 7 . ? -39.015 -5.740 7.384 1.00 38.98 ? 726 HOH A O 1 HETATM 7605 O O . HOH X 7 . ? -37.790 3.166 20.423 1.00 40.29 ? 727 HOH A O 1 HETATM 7606 O O . HOH X 7 . ? -36.834 -18.215 47.447 1.00 37.07 ? 728 HOH A O 1 HETATM 7607 O O . HOH X 7 . ? -28.978 7.328 13.916 1.00 30.14 ? 729 HOH A O 1 HETATM 7608 O O . HOH X 7 . ? -53.284 -13.174 26.764 1.00 49.48 ? 730 HOH A O 1 HETATM 7609 O O . HOH X 7 . ? -14.649 -25.293 26.828 1.00 41.15 ? 731 HOH A O 1 HETATM 7610 O O . HOH X 7 . ? -20.396 -17.756 -0.735 1.00 51.23 ? 732 HOH A O 1 HETATM 7611 O O . HOH X 7 . ? -29.936 -7.140 31.316 1.00 31.83 ? 733 HOH A O 1 HETATM 7612 O O . HOH X 7 . ? -37.653 -25.979 21.515 1.00 50.79 ? 734 HOH A O 1 HETATM 7613 O O . HOH X 7 . ? -39.301 1.589 29.629 1.00 32.37 ? 735 HOH A O 1 HETATM 7614 O O . HOH X 7 . ? -27.376 0.541 34.014 1.00 56.96 ? 736 HOH A O 1 HETATM 7615 O O . HOH X 7 . ? -20.975 -19.094 29.231 1.00 34.64 ? 737 HOH A O 1 HETATM 7616 O O . HOH X 7 . ? -8.839 -11.346 26.955 1.00 58.75 ? 738 HOH A O 1 HETATM 7617 O O . HOH X 7 . ? -23.402 -19.971 29.975 1.00 47.62 ? 739 HOH A O 1 HETATM 7618 O O . HOH X 7 . ? -49.121 1.070 32.283 1.00 38.79 ? 740 HOH A O 1 HETATM 7619 O O . HOH X 7 . ? -22.338 -10.557 37.049 1.00 36.95 ? 741 HOH A O 1 HETATM 7620 O O . HOH X 7 . ? -38.679 -0.258 3.051 1.00 56.53 ? 742 HOH A O 1 HETATM 7621 O O . HOH X 7 . ? -43.444 -5.772 15.806 1.00 51.59 ? 743 HOH A O 1 HETATM 7622 O O . HOH X 7 . ? -54.530 -12.494 39.829 1.00 45.99 ? 744 HOH A O 1 HETATM 7623 O O . HOH X 7 . ? -18.924 -30.190 10.740 1.00 57.47 ? 745 HOH A O 1 HETATM 7624 O O . HOH X 7 . ? -18.673 -19.187 30.424 1.00 45.67 ? 746 HOH A O 1 HETATM 7625 O O . HOH X 7 . ? -25.669 -8.672 30.626 1.00 47.46 ? 747 HOH A O 1 HETATM 7626 O O . HOH X 7 . ? -40.365 -10.528 48.824 1.00 45.25 ? 748 HOH A O 1 HETATM 7627 O O . HOH X 7 . ? -30.979 -28.003 19.095 1.00 52.40 ? 749 HOH A O 1 HETATM 7628 O O . HOH X 7 . ? -29.067 -0.951 13.048 1.00 33.76 ? 750 HOH A O 1 HETATM 7629 O O . HOH X 7 . ? -23.231 -11.531 48.347 1.00 54.97 ? 751 HOH A O 1 HETATM 7630 O O . HOH X 7 . ? -39.220 -4.648 25.624 1.00 24.97 ? 752 HOH A O 1 HETATM 7631 O O . HOH X 7 . ? -51.004 -2.809 38.964 1.00 52.05 ? 753 HOH A O 1 HETATM 7632 O O . HOH X 7 . ? -24.616 -6.604 32.227 1.00 43.07 ? 754 HOH A O 1 HETATM 7633 O O . HOH X 7 . ? -35.410 -1.874 8.495 1.00 48.37 ? 755 HOH A O 1 HETATM 7634 O O . HOH X 7 . ? -28.663 3.811 35.478 1.00 41.97 ? 756 HOH A O 1 HETATM 7635 O O . HOH X 7 . ? -37.259 -5.861 26.846 1.00 25.14 ? 757 HOH A O 1 HETATM 7636 O O . HOH X 7 . ? -39.162 -20.411 42.779 1.00 37.93 ? 758 HOH A O 1 HETATM 7637 O O . HOH X 7 . ? -35.136 -9.707 -0.685 1.00 40.34 ? 759 HOH A O 1 HETATM 7638 O O . HOH X 7 . ? -46.428 0.597 31.971 1.00 32.05 ? 760 HOH A O 1 HETATM 7639 O O . HOH X 7 . ? -44.439 -1.710 25.774 1.00 38.93 ? 761 HOH A O 1 HETATM 7640 O O . HOH X 7 . ? -28.029 -13.929 30.278 1.00 39.10 ? 762 HOH A O 1 HETATM 7641 O O . HOH X 7 . ? -39.325 -19.401 19.695 1.00 46.44 ? 763 HOH A O 1 HETATM 7642 O O . HOH X 7 . ? -40.102 -11.479 52.121 1.00 46.60 ? 764 HOH A O 1 HETATM 7643 O O . HOH X 7 . ? -27.502 -7.561 40.549 1.00 41.60 ? 765 HOH A O 1 HETATM 7644 O O . HOH X 7 . ? -20.705 -5.637 30.834 1.00 45.50 ? 766 HOH A O 1 HETATM 7645 O O . HOH X 7 . ? -12.785 -7.797 20.246 1.00 38.73 ? 767 HOH A O 1 HETATM 7646 O O . HOH X 7 . ? -34.486 -12.084 -6.938 1.00 61.18 ? 768 HOH A O 1 HETATM 7647 O O . HOH X 7 . ? -16.611 1.120 29.500 1.00 51.17 ? 769 HOH A O 1 HETATM 7648 O O . HOH X 7 . ? -36.611 -4.912 14.981 1.00 37.38 ? 770 HOH A O 1 HETATM 7649 O O . HOH X 7 . ? -43.624 -10.230 21.182 1.00 36.01 ? 771 HOH A O 1 HETATM 7650 O O . HOH X 7 . ? -43.065 -13.776 21.157 1.00 43.29 ? 772 HOH A O 1 HETATM 7651 O O . HOH X 7 . ? -25.481 1.993 2.798 1.00 45.02 ? 773 HOH A O 1 HETATM 7652 O O . HOH X 7 . ? -30.978 6.791 15.886 1.00 38.12 ? 774 HOH A O 1 HETATM 7653 O O . HOH X 7 . ? -19.054 -15.164 38.481 1.00 62.20 ? 775 HOH A O 1 HETATM 7654 O O . HOH X 7 . ? -39.759 0.311 33.586 1.00 42.49 ? 776 HOH A O 1 HETATM 7655 O O . HOH X 7 . ? -39.211 -34.035 44.542 1.00 65.68 ? 777 HOH A O 1 HETATM 7656 O O . HOH X 7 . ? -23.362 -10.003 45.755 1.00 44.40 ? 778 HOH A O 1 HETATM 7657 O O . HOH X 7 . ? -53.564 -9.876 26.686 1.00 49.15 ? 779 HOH A O 1 HETATM 7658 O O . HOH X 7 . ? -30.179 7.395 9.140 1.00 43.11 ? 780 HOH A O 1 HETATM 7659 O O . HOH X 7 . ? -41.614 -20.363 17.799 1.00 46.29 ? 781 HOH A O 1 HETATM 7660 O O . HOH X 7 . ? -35.756 3.968 6.319 1.00 41.73 ? 782 HOH A O 1 HETATM 7661 O O . HOH X 7 . ? -30.786 -0.220 44.986 1.00 51.15 ? 783 HOH A O 1 HETATM 7662 O O . HOH X 7 . ? -37.307 -13.291 -0.387 1.00 53.44 ? 784 HOH A O 1 HETATM 7663 O O . HOH X 7 . ? -40.338 -0.551 45.200 1.00 47.93 ? 785 HOH A O 1 HETATM 7664 O O . HOH X 7 . ? -12.437 -16.233 32.689 1.00 54.66 ? 786 HOH A O 1 HETATM 7665 O O . HOH X 7 . ? -40.934 0.877 20.615 1.00 38.40 ? 787 HOH A O 1 HETATM 7666 O O . HOH X 7 . ? -0.100 12.137 23.837 1.00 58.05 ? 788 HOH A O 1 HETATM 7667 O O . HOH X 7 . ? -24.138 -15.042 26.606 1.00 38.99 ? 789 HOH A O 1 HETATM 7668 O O . HOH X 7 . ? -41.429 -10.013 17.850 1.00 34.40 ? 790 HOH A O 1 HETATM 7669 O O . HOH X 7 . ? -46.995 -12.338 45.584 1.00 33.80 ? 791 HOH A O 1 HETATM 7670 O O . HOH X 7 . ? -41.558 1.542 13.467 1.00 39.44 ? 792 HOH A O 1 HETATM 7671 O O . HOH X 7 . ? -52.670 -0.876 31.778 1.00 43.65 ? 793 HOH A O 1 HETATM 7672 O O . HOH X 7 . ? -32.104 -29.218 31.556 1.00 51.28 ? 794 HOH A O 1 HETATM 7673 O O . HOH X 7 . ? -31.542 -18.328 26.997 1.00 38.42 ? 795 HOH A O 1 HETATM 7674 O O . HOH X 7 . ? -17.579 -7.691 35.326 1.00 48.53 ? 796 HOH A O 1 HETATM 7675 O O . HOH X 7 . ? -17.461 -27.761 26.600 1.00 45.54 ? 797 HOH A O 1 HETATM 7676 O O . HOH X 7 . ? -53.460 -16.763 27.646 1.00 45.12 ? 798 HOH A O 1 HETATM 7677 O O . HOH X 7 . ? -0.696 10.527 31.550 1.00 49.74 ? 799 HOH A O 1 HETATM 7678 O O . HOH X 7 . ? -45.514 -5.949 51.623 1.00 48.63 ? 800 HOH A O 1 HETATM 7679 O O . HOH X 7 . ? -11.299 -13.438 33.398 1.00 57.31 ? 801 HOH A O 1 HETATM 7680 O O . HOH X 7 . ? -42.309 -0.468 37.424 1.00 45.96 ? 802 HOH A O 1 HETATM 7681 O O . HOH X 7 . ? -47.743 -2.382 24.645 1.00 53.75 ? 803 HOH A O 1 HETATM 7682 O O . HOH X 7 . ? -38.745 -31.083 29.569 1.00 54.30 ? 804 HOH A O 1 HETATM 7683 O O . HOH X 7 . ? -42.455 -11.586 11.642 1.00 52.58 ? 805 HOH A O 1 HETATM 7684 O O . HOH X 7 . ? -21.888 -0.300 1.570 1.00 41.15 ? 806 HOH A O 1 HETATM 7685 O O . HOH X 7 . ? -19.530 -2.034 46.434 1.00 56.03 ? 807 HOH A O 1 HETATM 7686 O O . HOH X 7 . ? -29.451 0.308 28.026 1.00 26.55 ? 808 HOH A O 1 HETATM 7687 O O . HOH X 7 . ? -31.191 3.960 27.126 1.00 50.63 ? 809 HOH A O 1 HETATM 7688 O O . HOH X 7 . ? -53.083 -3.824 27.226 1.00 67.33 ? 810 HOH A O 1 HETATM 7689 O O . HOH X 7 . ? -30.674 -17.967 29.312 1.00 41.01 ? 811 HOH A O 1 HETATM 7690 O O . HOH X 7 . ? -25.363 5.513 20.046 1.00 37.34 ? 812 HOH A O 1 HETATM 7691 O O . HOH X 7 . ? -34.389 -6.372 55.995 1.00 58.89 ? 813 HOH A O 1 HETATM 7692 O O . HOH X 7 . ? -24.200 -12.406 28.093 1.00 49.66 ? 814 HOH A O 1 HETATM 7693 O O . HOH X 7 . ? -28.718 -4.548 27.692 1.00 39.12 ? 815 HOH A O 1 HETATM 7694 O O . HOH X 7 . ? -19.922 1.290 28.142 1.00 28.05 ? 816 HOH A O 1 HETATM 7695 O O . HOH X 7 . ? -22.284 -0.595 28.902 1.00 42.82 ? 817 HOH A O 1 HETATM 7696 O O . HOH X 7 . ? -38.688 -3.310 38.403 1.00 36.10 ? 818 HOH A O 1 HETATM 7697 O O . HOH X 7 . ? -14.138 -4.108 20.867 1.00 46.81 ? 819 HOH A O 1 HETATM 7698 O O . HOH X 7 . ? -26.903 -23.004 26.239 1.00 44.71 ? 820 HOH A O 1 HETATM 7699 O O . HOH X 7 . ? -49.967 -1.881 41.451 1.00 44.84 ? 821 HOH A O 1 HETATM 7700 O O . HOH X 7 . ? -2.129 -29.724 17.238 1.00 57.06 ? 822 HOH A O 1 HETATM 7701 O O . HOH X 7 . ? -61.094 -22.573 39.193 1.00 52.90 ? 823 HOH A O 1 HETATM 7702 O O . HOH X 7 . ? -25.744 -18.676 30.221 1.00 50.12 ? 824 HOH A O 1 HETATM 7703 O O . HOH X 7 . ? -42.030 -0.936 47.700 1.00 56.90 ? 825 HOH A O 1 HETATM 7704 O O . HOH X 7 . ? -44.463 -5.289 18.182 1.00 55.28 ? 826 HOH A O 1 HETATM 7705 O O . HOH X 7 . ? -23.908 -7.430 24.353 1.00 28.55 ? 827 HOH A O 1 HETATM 7706 O O . HOH X 7 . ? -35.304 -15.932 -0.716 1.00 62.76 ? 828 HOH A O 1 HETATM 7707 O O . HOH X 7 . ? -53.053 -28.557 34.171 1.00 45.73 ? 829 HOH A O 1 HETATM 7708 O O . HOH X 7 . ? -37.029 1.520 40.352 1.00 56.70 ? 830 HOH A O 1 HETATM 7709 O O . HOH X 7 . ? -27.893 1.675 -7.613 1.00 60.79 ? 831 HOH A O 1 HETATM 7710 O O . HOH X 7 . ? -26.661 -9.391 27.807 1.00 50.27 ? 832 HOH A O 1 HETATM 7711 O O . HOH X 7 . ? -25.644 -30.613 32.425 1.00 63.77 ? 833 HOH A O 1 HETATM 7712 O O . HOH X 7 . ? -28.878 9.475 7.862 1.00 62.57 ? 834 HOH A O 1 HETATM 7713 O O . HOH X 7 . ? -43.621 -8.449 16.986 1.00 52.42 ? 835 HOH A O 1 HETATM 7714 O O . HOH X 7 . ? -46.131 -29.405 29.318 1.00 53.04 ? 836 HOH A O 1 HETATM 7715 O O . HOH X 7 . ? -30.390 6.779 11.785 1.00 36.26 ? 837 HOH A O 1 HETATM 7716 O O . HOH X 7 . ? -45.244 -8.459 19.756 1.00 56.64 ? 838 HOH A O 1 HETATM 7717 O O . HOH X 7 . ? -54.410 -16.955 29.933 1.00 45.13 ? 839 HOH A O 1 HETATM 7718 O O . HOH X 7 . ? -20.645 -9.773 38.863 1.00 50.93 ? 840 HOH A O 1 HETATM 7719 O O . HOH X 7 . ? -45.310 0.106 23.922 1.00 58.66 ? 841 HOH A O 1 HETATM 7720 O O . HOH X 7 . ? -27.131 -27.750 30.012 1.00 63.13 ? 842 HOH A O 1 HETATM 7721 O O . HOH X 7 . ? -0.138 13.358 29.701 1.00 59.79 ? 843 HOH A O 1 HETATM 7722 O O . HOH X 7 . ? -34.394 11.021 20.577 1.00 51.91 ? 844 HOH A O 1 HETATM 7723 O O . HOH X 7 . ? -16.483 -28.802 10.659 1.00 64.24 ? 845 HOH A O 1 HETATM 7724 O O . HOH X 7 . ? -28.730 3.617 30.817 1.00 51.93 ? 846 HOH A O 1 HETATM 7725 O O . HOH X 7 . ? -44.251 1.213 33.714 1.00 53.38 ? 847 HOH A O 1 HETATM 7726 O O . HOH X 7 . ? -39.869 2.577 32.007 1.00 30.08 ? 848 HOH A O 1 HETATM 7727 O O . HOH X 7 . ? -25.320 -22.479 29.343 1.00 55.61 ? 849 HOH A O 1 HETATM 7728 O O . HOH X 7 . ? -21.374 -10.317 43.394 1.00 54.10 ? 850 HOH A O 1 HETATM 7729 O O . HOH X 7 . ? -11.409 -7.007 23.106 1.00 52.26 ? 851 HOH A O 1 HETATM 7730 O O . HOH X 7 . ? -20.799 -7.487 42.849 1.00 50.64 ? 852 HOH A O 1 HETATM 7731 O O . HOH X 7 . ? -30.300 2.190 45.742 1.00 58.96 ? 853 HOH A O 1 HETATM 7732 O O . HOH Y 7 . ? -9.330 22.662 20.656 1.00 51.85 ? 701 HOH B O 1 HETATM 7733 O O . HOH Y 7 . ? -21.547 4.848 26.929 1.00 42.54 ? 702 HOH B O 1 HETATM 7734 O O . HOH Y 7 . ? -40.244 28.083 21.510 1.00 45.65 ? 703 HOH B O 1 HETATM 7735 O O . HOH Y 7 . ? -27.803 17.820 37.282 1.00 43.33 ? 704 HOH B O 1 HETATM 7736 O O . HOH Y 7 . ? -55.189 24.317 35.933 1.00 41.76 ? 705 HOH B O 1 HETATM 7737 O O . HOH Y 7 . ? -58.274 14.347 39.081 1.00 37.21 ? 706 HOH B O 1 HETATM 7738 O O . HOH Y 7 . ? -26.634 13.405 41.323 1.00 47.89 ? 707 HOH B O 1 HETATM 7739 O O . HOH Y 7 . ? -36.956 36.097 15.171 1.00 36.81 ? 708 HOH B O 1 HETATM 7740 O O . HOH Y 7 . ? -12.050 25.496 40.406 1.00 37.45 ? 709 HOH B O 1 HETATM 7741 O O . HOH Y 7 . ? -29.330 22.483 9.920 1.00 40.64 ? 710 HOH B O 1 HETATM 7742 O O . HOH Y 7 . ? -56.073 16.616 15.376 1.00 54.88 ? 711 HOH B O 1 HETATM 7743 O O . HOH Y 7 . ? -35.482 28.688 45.752 1.00 61.37 ? 712 HOH B O 1 HETATM 7744 O O . HOH Y 7 . ? -39.638 14.190 25.110 1.00 25.91 ? 713 HOH B O 1 HETATM 7745 O O . HOH Y 7 . ? -44.453 17.820 17.069 1.00 36.00 ? 714 HOH B O 1 HETATM 7746 O O . HOH Y 7 . ? -60.071 5.961 30.475 1.00 37.06 ? 715 HOH B O 1 HETATM 7747 O O . HOH Y 7 . ? -40.037 9.321 48.673 1.00 64.63 ? 716 HOH B O 1 HETATM 7748 O O . HOH Y 7 . ? -30.608 7.709 22.131 1.00 40.25 ? 717 HOH B O 1 HETATM 7749 O O . HOH Y 7 . ? -43.995 3.726 45.653 1.00 48.24 ? 718 HOH B O 1 HETATM 7750 O O . HOH Y 7 . ? -47.225 27.024 49.971 1.00 48.36 ? 719 HOH B O 1 HETATM 7751 O O . HOH Y 7 . ? -51.940 16.074 51.657 1.00 42.92 ? 720 HOH B O 1 HETATM 7752 O O . HOH Y 7 . ? -47.496 12.282 14.888 1.00 47.15 ? 721 HOH B O 1 HETATM 7753 O O . HOH Y 7 . ? -34.816 18.723 36.096 1.00 39.69 ? 722 HOH B O 1 HETATM 7754 O O . HOH Y 7 . ? 5.997 9.513 38.820 1.00 60.70 ? 723 HOH B O 1 HETATM 7755 O O . HOH Y 7 . ? -48.771 23.650 18.019 1.00 35.21 ? 724 HOH B O 1 HETATM 7756 O O . HOH Y 7 . ? -17.032 20.205 40.235 1.00 34.51 ? 725 HOH B O 1 HETATM 7757 O O . HOH Y 7 . ? -23.820 35.003 7.926 1.00 59.78 ? 726 HOH B O 1 HETATM 7758 O O . HOH Y 7 . ? -37.974 37.597 18.275 1.00 48.23 ? 727 HOH B O 1 HETATM 7759 O O . HOH Y 7 . ? -38.628 16.441 21.444 1.00 40.82 ? 728 HOH B O 1 HETATM 7760 O O . HOH Y 7 . ? -24.659 14.148 34.912 1.00 32.78 ? 729 HOH B O 1 HETATM 7761 O O . HOH Y 7 . ? -10.424 22.594 37.982 1.00 28.23 ? 730 HOH B O 1 HETATM 7762 O O . HOH Y 7 . ? -60.082 5.483 33.036 1.00 45.34 ? 731 HOH B O 1 HETATM 7763 O O . HOH Y 7 . ? -36.458 12.300 32.771 1.00 27.13 ? 732 HOH B O 1 HETATM 7764 O O . HOH Y 7 . ? -43.768 3.784 34.506 1.00 33.86 ? 733 HOH B O 1 HETATM 7765 O O . HOH Y 7 . ? -33.304 36.434 33.017 1.00 38.05 ? 734 HOH B O 1 HETATM 7766 O O . HOH Y 7 . ? -53.170 15.305 16.174 1.00 44.34 ? 735 HOH B O 1 HETATM 7767 O O . HOH Y 7 . ? -35.985 31.161 0.881 1.00 62.15 ? 736 HOH B O 1 HETATM 7768 O O . HOH Y 7 . ? -37.142 31.893 38.598 1.00 57.11 ? 737 HOH B O 1 HETATM 7769 O O . HOH Y 7 . ? -59.181 12.513 32.087 1.00 42.93 ? 738 HOH B O 1 HETATM 7770 O O . HOH Y 7 . ? -5.107 25.904 39.271 1.00 52.03 ? 739 HOH B O 1 HETATM 7771 O O . HOH Y 7 . ? -62.245 7.218 35.628 1.00 43.72 ? 740 HOH B O 1 HETATM 7772 O O . HOH Y 7 . ? -38.090 25.114 29.664 1.00 44.02 ? 741 HOH B O 1 HETATM 7773 O O . HOH Y 7 . ? -28.063 4.888 33.032 1.00 39.88 ? 742 HOH B O 1 HETATM 7774 O O . HOH Y 7 . ? -51.485 2.137 27.019 1.00 57.66 ? 743 HOH B O 1 HETATM 7775 O O . HOH Y 7 . ? -14.790 5.261 27.478 1.00 43.78 ? 744 HOH B O 1 HETATM 7776 O O . HOH Y 7 . ? -19.321 7.147 28.046 1.00 41.35 ? 745 HOH B O 1 HETATM 7777 O O . HOH Y 7 . ? -37.735 18.746 32.737 1.00 39.01 ? 746 HOH B O 1 HETATM 7778 O O . HOH Y 7 . ? -37.092 25.967 32.436 1.00 36.19 ? 747 HOH B O 1 HETATM 7779 O O . HOH Y 7 . ? -31.505 26.554 41.780 1.00 56.56 ? 748 HOH B O 1 HETATM 7780 O O . HOH Y 7 . ? -37.381 11.567 8.201 1.00 64.09 ? 749 HOH B O 1 HETATM 7781 O O . HOH Y 7 . ? -25.310 21.672 11.619 1.00 31.80 ? 750 HOH B O 1 HETATM 7782 O O . HOH Y 7 . ? -40.266 25.187 31.816 1.00 36.89 ? 751 HOH B O 1 HETATM 7783 O O . HOH Y 7 . ? -23.692 34.927 16.246 1.00 45.42 ? 752 HOH B O 1 HETATM 7784 O O . HOH Y 7 . ? -67.811 0.287 23.414 1.00 69.07 ? 753 HOH B O 1 HETATM 7785 O O . HOH Y 7 . ? 7.276 9.901 41.112 1.00 65.65 ? 754 HOH B O 1 HETATM 7786 O O . HOH Y 7 . ? -35.703 14.804 45.522 1.00 42.34 ? 755 HOH B O 1 HETATM 7787 O O . HOH Y 7 . ? -7.696 29.523 38.090 1.00 48.10 ? 756 HOH B O 1 HETATM 7788 O O . HOH Y 7 . ? -37.054 15.315 25.259 1.00 27.00 ? 757 HOH B O 1 HETATM 7789 O O . HOH Y 7 . ? -20.204 12.428 27.395 1.00 24.36 ? 758 HOH B O 1 HETATM 7790 O O . HOH Y 7 . ? -46.689 -0.620 42.095 1.00 37.72 ? 759 HOH B O 1 HETATM 7791 O O . HOH Y 7 . ? -60.221 24.150 30.189 1.00 49.42 ? 760 HOH B O 1 HETATM 7792 O O . HOH Y 7 . ? -53.187 13.315 48.676 1.00 51.66 ? 761 HOH B O 1 HETATM 7793 O O . HOH Y 7 . ? -37.612 38.777 15.758 1.00 46.95 ? 762 HOH B O 1 HETATM 7794 O O . HOH Y 7 . ? -48.027 6.593 35.730 1.00 32.86 ? 763 HOH B O 1 HETATM 7795 O O . HOH Y 7 . ? -19.203 4.569 25.479 1.00 33.32 ? 764 HOH B O 1 HETATM 7796 O O . HOH Y 7 . ? -28.644 29.451 7.474 1.00 48.64 ? 765 HOH B O 1 HETATM 7797 O O . HOH Y 7 . ? -36.689 12.450 45.499 1.00 51.16 ? 766 HOH B O 1 HETATM 7798 O O . HOH Y 7 . ? -23.794 20.146 42.126 1.00 42.82 ? 767 HOH B O 1 HETATM 7799 O O . HOH Y 7 . ? -36.657 10.223 37.129 1.00 27.54 ? 768 HOH B O 1 HETATM 7800 O O . HOH Y 7 . ? -44.028 30.642 -3.652 1.00 41.66 ? 769 HOH B O 1 HETATM 7801 O O . HOH Y 7 . ? -33.071 25.690 38.252 1.00 39.68 ? 770 HOH B O 1 HETATM 7802 O O . HOH Y 7 . ? -39.930 34.241 29.701 1.00 53.30 ? 771 HOH B O 1 HETATM 7803 O O . HOH Y 7 . ? -23.877 43.058 24.043 1.00 61.51 ? 772 HOH B O 1 HETATM 7804 O O . HOH Y 7 . ? -9.877 33.825 26.096 1.00 46.71 ? 773 HOH B O 1 HETATM 7805 O O . HOH Y 7 . ? -36.182 21.224 21.192 1.00 42.85 ? 774 HOH B O 1 HETATM 7806 O O . HOH Y 7 . ? -3.051 21.617 35.281 1.00 45.47 ? 775 HOH B O 1 HETATM 7807 O O . HOH Y 7 . ? -45.164 33.488 43.159 1.00 53.50 ? 776 HOH B O 1 HETATM 7808 O O . HOH Y 7 . ? -39.767 20.993 24.444 1.00 36.25 ? 777 HOH B O 1 HETATM 7809 O O . HOH Y 7 . ? -52.265 4.153 41.154 1.00 52.49 ? 778 HOH B O 1 HETATM 7810 O O . HOH Y 7 . ? -40.387 24.527 27.819 1.00 36.25 ? 779 HOH B O 1 HETATM 7811 O O . HOH Y 7 . ? -46.771 18.059 49.646 1.00 43.27 ? 780 HOH B O 1 HETATM 7812 O O . HOH Y 7 . ? -31.135 27.927 35.014 1.00 52.55 ? 781 HOH B O 1 HETATM 7813 O O . HOH Y 7 . ? -40.066 26.863 10.117 1.00 40.61 ? 782 HOH B O 1 HETATM 7814 O O . HOH Y 7 . ? -28.987 6.508 36.744 1.00 48.04 ? 783 HOH B O 1 HETATM 7815 O O . HOH Y 7 . ? -49.704 3.652 39.754 1.00 51.45 ? 784 HOH B O 1 HETATM 7816 O O . HOH Y 7 . ? -56.713 30.561 43.319 1.00 57.63 ? 785 HOH B O 1 HETATM 7817 O O . HOH Y 7 . ? -37.527 30.341 29.209 1.00 49.44 ? 786 HOH B O 1 HETATM 7818 O O . HOH Y 7 . ? -39.709 28.495 16.758 1.00 38.40 ? 787 HOH B O 1 HETATM 7819 O O . HOH Y 7 . ? -28.836 23.078 38.125 1.00 57.78 ? 788 HOH B O 1 HETATM 7820 O O . HOH Y 7 . ? -12.664 20.993 44.220 1.00 62.40 ? 789 HOH B O 1 HETATM 7821 O O . HOH Y 7 . ? -47.695 7.709 31.554 1.00 29.48 ? 790 HOH B O 1 HETATM 7822 O O . HOH Y 7 . ? -35.897 24.159 22.110 1.00 38.25 ? 791 HOH B O 1 HETATM 7823 O O . HOH Y 7 . ? -58.620 20.716 29.253 1.00 37.48 ? 792 HOH B O 1 HETATM 7824 O O . HOH Y 7 . ? -50.215 5.097 24.688 1.00 53.84 ? 793 HOH B O 1 HETATM 7825 O O . HOH Y 7 . ? -41.817 4.385 32.487 1.00 33.40 ? 794 HOH B O 1 HETATM 7826 O O . HOH Y 7 . ? 3.689 20.328 36.444 1.00 45.45 ? 795 HOH B O 1 HETATM 7827 O O . HOH Y 7 . ? -54.935 23.233 33.300 1.00 40.45 ? 796 HOH B O 1 HETATM 7828 O O . HOH Y 7 . ? -38.935 28.280 19.477 1.00 31.88 ? 797 HOH B O 1 HETATM 7829 O O . HOH Y 7 . ? -37.020 6.163 36.551 1.00 31.04 ? 798 HOH B O 1 HETATM 7830 O O . HOH Y 7 . ? -9.042 12.848 26.040 1.00 36.45 ? 799 HOH B O 1 HETATM 7831 O O . HOH Y 7 . ? -47.934 3.525 30.826 1.00 48.03 ? 800 HOH B O 1 HETATM 7832 O O . HOH Y 7 . ? -25.270 16.773 11.380 1.00 49.88 ? 801 HOH B O 1 HETATM 7833 O O . HOH Y 7 . ? -37.200 16.930 46.867 1.00 45.40 ? 802 HOH B O 1 HETATM 7834 O O . HOH Y 7 . ? -3.947 20.712 37.791 1.00 42.56 ? 803 HOH B O 1 HETATM 7835 O O . HOH Y 7 . ? -32.867 23.221 48.096 1.00 46.50 ? 804 HOH B O 1 HETATM 7836 O O . HOH Y 7 . ? -39.990 12.405 48.954 1.00 45.80 ? 805 HOH B O 1 HETATM 7837 O O . HOH Y 7 . ? -38.530 0.915 38.160 1.00 54.60 ? 806 HOH B O 1 HETATM 7838 O O . HOH Y 7 . ? -46.255 38.014 23.292 1.00 70.83 ? 807 HOH B O 1 HETATM 7839 O O . HOH Y 7 . ? -35.317 10.770 34.711 1.00 23.21 ? 808 HOH B O 1 HETATM 7840 O O . HOH Y 7 . ? -34.774 8.165 24.051 1.00 34.70 ? 809 HOH B O 1 HETATM 7841 O O . HOH Y 7 . ? -29.191 12.265 9.538 1.00 48.76 ? 810 HOH B O 1 HETATM 7842 O O . HOH Y 7 . ? -19.998 25.209 47.121 1.00 54.11 ? 811 HOH B O 1 HETATM 7843 O O . HOH Y 7 . ? -35.906 5.535 23.537 1.00 50.00 ? 812 HOH B O 1 HETATM 7844 O O . HOH Y 7 . ? -32.260 9.665 14.690 1.00 38.75 ? 813 HOH B O 1 HETATM 7845 O O . HOH Y 7 . ? -29.888 40.330 28.524 1.00 45.18 ? 814 HOH B O 1 HETATM 7846 O O . HOH Y 7 . ? -30.140 39.201 31.392 1.00 42.49 ? 815 HOH B O 1 HETATM 7847 O O . HOH Y 7 . ? -34.000 10.974 17.323 1.00 38.33 ? 816 HOH B O 1 HETATM 7848 O O . HOH Y 7 . ? -49.669 1.825 29.173 1.00 45.82 ? 817 HOH B O 1 HETATM 7849 O O . HOH Y 7 . ? -13.379 23.450 46.124 1.00 52.74 ? 818 HOH B O 1 HETATM 7850 O O . HOH Y 7 . ? -7.718 15.965 23.263 1.00 41.93 ? 819 HOH B O 1 HETATM 7851 O O . HOH Y 7 . ? -7.967 36.657 26.292 1.00 52.88 ? 820 HOH B O 1 HETATM 7852 O O . HOH Y 7 . ? -36.835 3.995 34.950 1.00 27.95 ? 821 HOH B O 1 HETATM 7853 O O . HOH Y 7 . ? -18.580 13.007 34.430 1.00 58.65 ? 822 HOH B O 1 HETATM 7854 O O . HOH Y 7 . ? -20.789 32.155 46.895 1.00 57.72 ? 823 HOH B O 1 HETATM 7855 O O . HOH Y 7 . ? -1.010 14.968 32.419 1.00 46.18 ? 824 HOH B O 1 HETATM 7856 O O . HOH Y 7 . ? -45.038 2.650 23.595 1.00 51.59 ? 825 HOH B O 1 HETATM 7857 O O . HOH Y 7 . ? -29.973 31.388 38.913 1.00 60.11 ? 826 HOH B O 1 HETATM 7858 O O . HOH Y 7 . ? -59.151 30.162 39.019 1.00 45.05 ? 827 HOH B O 1 HETATM 7859 O O . HOH Y 7 . ? -0.737 18.208 28.909 1.00 57.80 ? 828 HOH B O 1 HETATM 7860 O O . HOH Y 7 . ? -51.526 3.967 45.601 1.00 59.85 ? 829 HOH B O 1 HETATM 7861 O O . HOH Y 7 . ? -31.678 17.770 21.066 1.00 28.99 ? 830 HOH B O 1 HETATM 7862 O O . HOH Y 7 . ? -33.852 12.995 22.680 1.00 37.95 ? 831 HOH B O 1 HETATM 7863 O O . HOH Y 7 . ? -35.283 12.413 24.669 1.00 39.84 ? 832 HOH B O 1 HETATM 7864 O O . HOH Y 7 . ? -12.867 32.678 18.238 1.00 53.13 ? 833 HOH B O 1 HETATM 7865 O O . HOH Y 7 . ? -37.230 14.781 16.046 1.00 45.13 ? 834 HOH B O 1 HETATM 7866 O O . HOH Y 7 . ? -36.590 6.244 39.226 1.00 46.15 ? 835 HOH B O 1 HETATM 7867 O O . HOH Y 7 . ? -29.305 17.247 39.938 1.00 33.51 ? 836 HOH B O 1 HETATM 7868 O O . HOH Y 7 . ? -14.617 35.911 20.159 1.00 58.50 ? 837 HOH B O 1 HETATM 7869 O O . HOH Y 7 . ? -51.842 1.894 31.358 1.00 47.55 ? 838 HOH B O 1 HETATM 7870 O O . HOH Y 7 . ? -43.638 27.879 17.624 1.00 58.18 ? 839 HOH B O 1 HETATM 7871 O O . HOH Y 7 . ? -25.684 24.616 42.443 1.00 61.62 ? 840 HOH B O 1 HETATM 7872 O O . HOH Y 7 . ? -43.181 1.787 43.440 1.00 47.07 ? 841 HOH B O 1 HETATM 7873 O O . HOH Y 7 . ? -48.933 3.578 26.409 1.00 51.64 ? 842 HOH B O 1 HETATM 7874 O O . HOH Y 7 . ? -37.702 29.271 51.433 1.00 55.94 ? 843 HOH B O 1 HETATM 7875 O O . HOH Y 7 . ? -27.661 10.966 41.531 1.00 49.80 ? 844 HOH B O 1 HETATM 7876 O O . HOH Y 7 . ? -36.422 4.585 29.606 1.00 37.80 ? 845 HOH B O 1 HETATM 7877 O O . HOH Y 7 . ? -37.595 4.424 32.354 1.00 28.04 ? 846 HOH B O 1 HETATM 7878 O O . HOH Y 7 . ? -38.212 30.872 26.679 1.00 55.02 ? 847 HOH B O 1 HETATM 7879 O O . HOH Y 7 . ? -24.309 39.666 36.370 1.00 59.02 ? 848 HOH B O 1 HETATM 7880 O O . HOH Y 7 . ? -56.519 4.144 47.368 1.00 56.21 ? 849 HOH B O 1 HETATM 7881 O O . HOH Y 7 . ? -39.723 25.740 22.888 1.00 45.10 ? 850 HOH B O 1 HETATM 7882 O O . HOH Y 7 . ? -30.408 12.116 41.892 1.00 63.34 ? 851 HOH B O 1 HETATM 7883 O O . HOH Y 7 . ? -4.804 22.118 39.930 1.00 54.71 ? 852 HOH B O 1 HETATM 7884 O O . HOH Y 7 . ? -52.061 3.542 35.637 1.00 64.96 ? 853 HOH B O 1 HETATM 7885 O O . HOH Y 7 . ? -42.265 0.005 34.891 1.00 44.24 ? 854 HOH B O 1 HETATM 7886 O O . HOH Y 7 . ? -17.526 5.134 27.223 1.00 36.97 ? 855 HOH B O 1 HETATM 7887 O O . HOH Y 7 . ? -56.468 2.797 31.698 1.00 51.71 ? 856 HOH B O 1 HETATM 7888 O O . HOH Y 7 . ? -18.216 13.733 36.961 1.00 56.50 ? 857 HOH B O 1 HETATM 7889 O O . HOH Y 7 . ? -33.691 24.210 50.508 1.00 55.85 ? 858 HOH B O 1 HETATM 7890 O O . HOH Y 7 . ? -14.081 17.857 43.990 1.00 53.92 ? 859 HOH B O 1 HETATM 7891 O O . HOH Y 7 . ? -49.364 4.243 36.751 1.00 34.48 ? 860 HOH B O 1 HETATM 7892 O O . HOH Y 7 . ? -36.539 17.179 23.088 1.00 39.11 ? 861 HOH B O 1 HETATM 7893 O O . HOH Y 7 . ? -37.856 19.928 22.686 1.00 56.09 ? 862 HOH B O 1 HETATM 7894 O O . HOH Y 7 . ? -28.903 5.136 28.371 1.00 43.76 ? 863 HOH B O 1 HETATM 7895 O O . HOH Y 7 . ? -46.229 4.659 34.703 1.00 54.21 ? 864 HOH B O 1 HETATM 7896 O O . HOH Y 7 . ? -46.255 5.588 31.872 1.00 32.20 ? 865 HOH B O 1 HETATM 7897 O O . HOH Y 7 . ? -32.777 38.534 31.497 1.00 45.00 ? 866 HOH B O 1 HETATM 7898 O O . HOH Y 7 . ? -28.067 20.519 9.379 1.00 47.60 ? 867 HOH B O 1 HETATM 7899 O O . HOH Y 7 . ? -37.775 1.353 35.405 1.00 37.19 ? 868 HOH B O 1 HETATM 7900 O O . HOH Y 7 . ? -41.951 29.972 16.590 1.00 53.45 ? 869 HOH B O 1 HETATM 7901 O O . HOH Y 7 . ? -28.830 28.717 4.468 1.00 59.40 ? 870 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 MET 1 -26 ? ? ? A . n A 1 2 ARG 2 -25 ? ? ? A . n A 1 3 LEU 3 -24 ? ? ? A . n A 1 4 LEU 4 -23 ? ? ? A . n A 1 5 THR 5 -22 ? ? ? A . n A 1 6 ALA 6 -21 ? ? ? A . n A 1 7 LEU 7 -20 ? ? ? A . n A 1 8 PHE 8 -19 ? ? ? A . n A 1 9 ALA 9 -18 ? ? ? A . n A 1 10 TYR 10 -17 ? ? ? A . n A 1 11 PHE 11 -16 ? ? ? A . n A 1 12 ILE 12 -15 ? ? ? A . n A 1 13 VAL 13 -14 ? ? ? A . n A 1 14 ALA 14 -13 ? ? ? A . n A 1 15 LEU 15 -12 ? ? ? A . n A 1 16 ILE 16 -11 ? ? ? A . n A 1 17 LEU 17 -10 ? ? ? A . n A 1 18 ALA 18 -9 ? ? ? A . n A 1 19 PHE 19 -8 ? ? ? A . n A 1 20 SER 20 -7 ? ? ? A . n A 1 21 VAL 21 -6 ? ? ? A . n A 1 22 SER 22 -5 ? ? ? A . n A 1 23 ALA 23 -4 ? ? ? A . n A 1 24 LYS 24 -3 ? ? ? A . n A 1 25 SER 25 -2 ? ? ? A . n A 1 26 MET 26 -1 ? ? ? A . n A 1 27 HIS 27 0 ? ? ? A . n A 1 28 HIS 28 1 ? ? ? A . n A 1 29 HIS 29 2 ? ? ? A . n A 1 30 HIS 30 3 ? ? ? A . n A 1 31 HIS 31 4 ? ? ? A . n A 1 32 HIS 32 5 ? ? ? A . n A 1 33 HIS 33 6 ? ? ? A . n A 1 34 HIS 34 7 ? ? ? A . n A 1 35 SER 35 8 ? ? ? A . n A 1 36 ALA 36 9 ? ? ? A . n A 1 37 TRP 37 10 ? ? ? A . n A 1 38 SER 38 11 ? ? ? A . n A 1 39 HIS 39 12 ? ? ? A . n A 1 40 PRO 40 13 ? ? ? A . n A 1 41 GLN 41 14 ? ? ? A . n A 1 42 PHE 42 15 ? ? ? A . n A 1 43 GLU 43 16 ? ? ? A . n A 1 44 LYS 44 17 ? ? ? A . n A 1 45 GLU 45 18 ? ? ? A . n A 1 46 PHE 46 19 ? ? ? A . n A 1 47 TYR 47 20 ? ? ? A . n A 1 48 GLY 48 21 ? ? ? A . n A 1 49 PRO 49 22 22 PRO PRO A . n A 1 50 ASP 50 23 23 ASP ASP A . n A 1 51 GLN 51 24 24 GLN GLN A . n A 1 52 ARG 52 25 25 ARG ARG A . n A 1 53 ALA 53 26 26 ALA ALA A . n A 1 54 GLN 54 27 27 GLN GLN A . n A 1 55 LYS 55 28 28 LYS LYS A . n A 1 56 LYS 56 29 29 LYS LYS A . n A 1 57 GLY 57 30 30 GLY GLY A . n A 1 58 ASP 58 31 31 ASP ASP A . n A 1 59 ILE 59 32 32 ILE ILE A . n A 1 60 ILE 60 33 33 ILE ILE A . n A 1 61 LEU 61 34 34 LEU LEU A . n A 1 62 GLY 62 35 35 GLY GLY A . n A 1 63 GLY 63 36 36 GLY GLY A . n A 1 64 LEU 64 37 37 LEU LEU A . n A 1 65 PHE 65 38 38 PHE PHE A . n A 1 66 PRO 66 39 39 PRO PRO A . n A 1 67 ILE 67 40 40 ILE ILE A . n A 1 68 HIS 68 41 41 HIS HIS A . n A 1 69 PHE 69 42 42 PHE PHE A . n A 1 70 GLY 70 43 43 GLY GLY A . n A 1 71 VAL 71 44 44 VAL VAL A . n A 1 72 ALA 72 45 45 ALA ALA A . n A 1 73 ALA 73 46 46 ALA ALA A . n A 1 74 LYS 74 47 47 LYS LYS A . n A 1 75 ASP 75 48 48 ASP ASP A . n A 1 76 GLN 76 49 49 GLN GLN A . n A 1 77 ASP 77 50 50 ASP ASP A . n A 1 78 LEU 78 51 51 LEU LEU A . n A 1 79 LYS 79 52 52 LYS LYS A . n A 1 80 SER 80 53 53 SER SER A . n A 1 81 ARG 81 54 54 ARG ARG A . n A 1 82 PRO 82 55 55 PRO PRO A . n A 1 83 GLU 83 56 56 GLU GLU A . n A 1 84 SER 84 57 57 SER SER A . n A 1 85 VAL 85 58 58 VAL VAL A . n A 1 86 GLU 86 59 59 GLU GLU A . n A 1 87 CYS 87 60 60 CYS CYS A . n A 1 88 ILE 88 61 61 ILE ILE A . n A 1 89 ARG 89 62 62 ARG ARG A . n A 1 90 TYR 90 63 63 TYR TYR A . n A 1 91 ASN 91 64 64 ASN ASN A . n A 1 92 PHE 92 65 65 PHE PHE A . n A 1 93 ARG 93 66 66 ARG ARG A . n A 1 94 GLY 94 67 67 GLY GLY A . n A 1 95 PHE 95 68 68 PHE PHE A . n A 1 96 ARG 96 69 69 ARG ARG A . n A 1 97 TRP 97 70 70 TRP TRP A . n A 1 98 LEU 98 71 71 LEU LEU A . n A 1 99 GLN 99 72 72 GLN GLN A . n A 1 100 ALA 100 73 73 ALA ALA A . n A 1 101 MET 101 74 74 MET MET A . n A 1 102 ILE 102 75 75 ILE ILE A . n A 1 103 PHE 103 76 76 PHE PHE A . n A 1 104 ALA 104 77 77 ALA ALA A . n A 1 105 ILE 105 78 78 ILE ILE A . n A 1 106 GLU 106 79 79 GLU GLU A . n A 1 107 GLU 107 80 80 GLU GLU A . n A 1 108 ILE 108 81 81 ILE ILE A . n A 1 109 ASN 109 82 82 ASN ASN A . n A 1 110 SER 110 83 83 SER SER A . n A 1 111 SER 111 84 84 SER SER A . n A 1 112 PRO 112 85 85 PRO PRO A . n A 1 113 ALA 113 86 86 ALA ALA A . n A 1 114 LEU 114 87 87 LEU LEU A . n A 1 115 LEU 115 88 88 LEU LEU A . n A 1 116 PRO 116 89 89 PRO PRO A . n A 1 117 ASN 117 90 90 ASN ASN A . n A 1 118 LEU 118 91 91 LEU LEU A . n A 1 119 THR 119 92 92 THR THR A . n A 1 120 LEU 120 93 93 LEU LEU A . n A 1 121 GLY 121 94 94 GLY GLY A . n A 1 122 TYR 122 95 95 TYR TYR A . n A 1 123 ARG 123 96 96 ARG ARG A . n A 1 124 ILE 124 97 97 ILE ILE A . n A 1 125 PHE 125 98 98 PHE PHE A . n A 1 126 ASP 126 99 99 ASP ASP A . n A 1 127 THR 127 100 100 THR THR A . n A 1 128 CYS 128 101 101 CYS CYS A . n A 1 129 ASN 129 102 102 ASN ASN A . n A 1 130 THR 130 103 103 THR THR A . n A 1 131 VAL 131 104 104 VAL VAL A . n A 1 132 SER 132 105 105 SER SER A . n A 1 133 LYS 133 106 106 LYS LYS A . n A 1 134 ALA 134 107 107 ALA ALA A . n A 1 135 LEU 135 108 108 LEU LEU A . n A 1 136 GLU 136 109 109 GLU GLU A . n A 1 137 ALA 137 110 110 ALA ALA A . n A 1 138 THR 138 111 111 THR THR A . n A 1 139 LEU 139 112 112 LEU LEU A . n A 1 140 SER 140 113 113 SER SER A . n A 1 141 PHE 141 114 114 PHE PHE A . n A 1 142 VAL 142 115 115 VAL VAL A . n A 1 143 ALA 143 116 116 ALA ALA A . n A 1 144 GLN 144 117 117 GLN GLN A . n A 1 145 ASN 145 118 118 ASN ASN A . n A 1 146 LYS 146 119 119 LYS LYS A . n A 1 147 ILE 147 120 120 ILE ILE A . n A 1 148 ASP 148 121 121 ASP ASP A . n A 1 149 SER 149 122 122 SER SER A . n A 1 150 LEU 150 123 123 LEU LEU A . n A 1 151 ASN 151 124 124 ASN ASN A . n A 1 152 LEU 152 125 125 LEU LEU A . n A 1 153 ASP 153 126 126 ASP ASP A . n A 1 154 GLU 154 127 127 GLU GLU A . n A 1 155 PHE 155 128 128 PHE PHE A . n A 1 156 CYS 156 129 129 CYS CYS A . n A 1 157 ASN 157 130 130 ASN ASN A . n A 1 158 CYS 158 131 131 CYS CYS A . n A 1 159 SER 159 132 132 SER SER A . n A 1 160 GLU 160 133 133 GLU GLU A . n A 1 161 HIS 161 134 134 HIS HIS A . n A 1 162 ILE 162 135 135 ILE ILE A . n A 1 163 PRO 163 136 136 PRO PRO A . n A 1 164 SER 164 137 137 SER SER A . n A 1 165 THR 165 138 138 THR THR A . n A 1 166 ILE 166 139 139 ILE ILE A . n A 1 167 ALA 167 140 140 ALA ALA A . n A 1 168 VAL 168 141 141 VAL VAL A . n A 1 169 VAL 169 142 142 VAL VAL A . n A 1 170 GLY 170 143 143 GLY GLY A . n A 1 171 ALA 171 144 144 ALA ALA A . n A 1 172 THR 172 145 145 THR THR A . n A 1 173 GLY 173 146 146 GLY GLY A . n A 1 174 SER 174 147 147 SER SER A . n A 1 175 GLY 175 148 148 GLY GLY A . n A 1 176 VAL 176 149 149 VAL VAL A . n A 1 177 SER 177 150 150 SER SER A . n A 1 178 THR 178 151 151 THR THR A . n A 1 179 ALA 179 152 152 ALA ALA A . n A 1 180 VAL 180 153 153 VAL VAL A . n A 1 181 ALA 181 154 154 ALA ALA A . n A 1 182 ASN 182 155 155 ASN ASN A . n A 1 183 LEU 183 156 156 LEU LEU A . n A 1 184 LEU 184 157 157 LEU LEU A . n A 1 185 GLY 185 158 158 GLY GLY A . n A 1 186 LEU 186 159 159 LEU LEU A . n A 1 187 PHE 187 160 160 PHE PHE A . n A 1 188 TYR 188 161 161 TYR TYR A . n A 1 189 ILE 189 162 162 ILE ILE A . n A 1 190 PRO 190 163 163 PRO PRO A . n A 1 191 GLN 191 164 164 GLN GLN A . n A 1 192 VAL 192 165 165 VAL VAL A . n A 1 193 SER 193 166 166 SER SER A . n A 1 194 TYR 194 167 167 TYR TYR A . n A 1 195 ALA 195 168 168 ALA ALA A . n A 1 196 SER 196 169 169 SER SER A . n A 1 197 SER 197 170 170 SER SER A . n A 1 198 SER 198 171 171 SER SER A . n A 1 199 ARG 199 172 172 ARG ARG A . n A 1 200 LEU 200 173 173 LEU LEU A . n A 1 201 LEU 201 174 174 LEU LEU A . n A 1 202 SER 202 175 175 SER SER A . n A 1 203 ASN 203 176 176 ASN ASN A . n A 1 204 LYS 204 177 177 LYS LYS A . n A 1 205 ASN 205 178 178 ASN ASN A . n A 1 206 GLN 206 179 179 GLN GLN A . n A 1 207 PHE 207 180 180 PHE PHE A . n A 1 208 LYS 208 181 181 LYS LYS A . n A 1 209 SER 209 182 182 SER SER A . n A 1 210 PHE 210 183 183 PHE PHE A . n A 1 211 LEU 211 184 184 LEU LEU A . n A 1 212 ARG 212 185 185 ARG ARG A . n A 1 213 THR 213 186 186 THR THR A . n A 1 214 ILE 214 187 187 ILE ILE A . n A 1 215 PRO 215 188 188 PRO PRO A . n A 1 216 ASN 216 189 189 ASN ASN A . n A 1 217 ASP 217 190 190 ASP ASP A . n A 1 218 GLU 218 191 191 GLU GLU A . n A 1 219 HIS 219 192 192 HIS HIS A . n A 1 220 GLN 220 193 193 GLN GLN A . n A 1 221 ALA 221 194 194 ALA ALA A . n A 1 222 THR 222 195 195 THR THR A . n A 1 223 ALA 223 196 196 ALA ALA A . n A 1 224 MET 224 197 197 MET MET A . n A 1 225 ALA 225 198 198 ALA ALA A . n A 1 226 ASP 226 199 199 ASP ASP A . n A 1 227 ILE 227 200 200 ILE ILE A . n A 1 228 ILE 228 201 201 ILE ILE A . n A 1 229 GLU 229 202 202 GLU GLU A . n A 1 230 TYR 230 203 203 TYR TYR A . n A 1 231 PHE 231 204 204 PHE PHE A . n A 1 232 ARG 232 205 205 ARG ARG A . n A 1 233 TRP 233 206 206 TRP TRP A . n A 1 234 ASN 234 207 207 ASN ASN A . n A 1 235 TRP 235 208 208 TRP TRP A . n A 1 236 VAL 236 209 209 VAL VAL A . n A 1 237 GLY 237 210 210 GLY GLY A . n A 1 238 THR 238 211 211 THR THR A . n A 1 239 ILE 239 212 212 ILE ILE A . n A 1 240 ALA 240 213 213 ALA ALA A . n A 1 241 ALA 241 214 214 ALA ALA A . n A 1 242 ASP 242 215 215 ASP ASP A . n A 1 243 ASP 243 216 216 ASP ASP A . n A 1 244 ASP 244 217 217 ASP ASP A . n A 1 245 TYR 245 218 218 TYR TYR A . n A 1 246 GLY 246 219 219 GLY GLY A . n A 1 247 ARG 247 220 220 ARG ARG A . n A 1 248 PRO 248 221 221 PRO PRO A . n A 1 249 GLY 249 222 222 GLY GLY A . n A 1 250 ILE 250 223 223 ILE ILE A . n A 1 251 GLU 251 224 224 GLU GLU A . n A 1 252 LYS 252 225 225 LYS LYS A . n A 1 253 PHE 253 226 226 PHE PHE A . n A 1 254 ARG 254 227 227 ARG ARG A . n A 1 255 GLU 255 228 228 GLU GLU A . n A 1 256 GLU 256 229 229 GLU GLU A . n A 1 257 ALA 257 230 230 ALA ALA A . n A 1 258 GLU 258 231 231 GLU GLU A . n A 1 259 GLU 259 232 232 GLU GLU A . n A 1 260 ARG 260 233 233 ARG ARG A . n A 1 261 ASP 261 234 234 ASP ASP A . n A 1 262 ILE 262 235 235 ILE ILE A . n A 1 263 CSO 263 236 236 CSO CSO A . n A 1 264 ILE 264 237 237 ILE ILE A . n A 1 265 ASP 265 238 238 ASP ASP A . n A 1 266 PHE 266 239 239 PHE PHE A . n A 1 267 SER 267 240 240 SER SER A . n A 1 268 GLU 268 241 241 GLU GLU A . n A 1 269 LEU 269 242 242 LEU LEU A . n A 1 270 ILE 270 243 243 ILE ILE A . n A 1 271 SER 271 244 244 SER SER A . n A 1 272 GLN 272 245 245 GLN GLN A . n A 1 273 TYR 273 246 246 TYR TYR A . n A 1 274 SER 274 247 247 SER SER A . n A 1 275 ASP 275 248 248 ASP ASP A . n A 1 276 GLU 276 249 249 GLU GLU A . n A 1 277 GLU 277 250 250 GLU GLU A . n A 1 278 GLU 278 251 251 GLU GLU A . n A 1 279 ILE 279 252 252 ILE ILE A . n A 1 280 GLN 280 253 253 GLN GLN A . n A 1 281 HIS 281 254 254 HIS HIS A . n A 1 282 VAL 282 255 255 VAL VAL A . n A 1 283 VAL 283 256 256 VAL VAL A . n A 1 284 GLU 284 257 257 GLU GLU A . n A 1 285 VAL 285 258 258 VAL VAL A . n A 1 286 ILE 286 259 259 ILE ILE A . n A 1 287 GLN 287 260 260 GLN GLN A . n A 1 288 ASN 288 261 261 ASN ASN A . n A 1 289 SER 289 262 262 SER SER A . n A 1 290 THR 290 263 263 THR THR A . n A 1 291 ALA 291 264 264 ALA ALA A . n A 1 292 LYS 292 265 265 LYS LYS A . n A 1 293 VAL 293 266 266 VAL VAL A . n A 1 294 ILE 294 267 267 ILE ILE A . n A 1 295 VAL 295 268 268 VAL VAL A . n A 1 296 VAL 296 269 269 VAL VAL A . n A 1 297 PHE 297 270 270 PHE PHE A . n A 1 298 SER 298 271 271 SER SER A . n A 1 299 SER 299 272 272 SER SER A . n A 1 300 GLY 300 273 273 GLY GLY A . n A 1 301 PRO 301 274 274 PRO PRO A . n A 1 302 ASP 302 275 275 ASP ASP A . n A 1 303 LEU 303 276 276 LEU LEU A . n A 1 304 GLU 304 277 277 GLU GLU A . n A 1 305 PRO 305 278 278 PRO PRO A . n A 1 306 LEU 306 279 279 LEU LEU A . n A 1 307 ILE 307 280 280 ILE ILE A . n A 1 308 LYS 308 281 281 LYS LYS A . n A 1 309 GLU 309 282 282 GLU GLU A . n A 1 310 ILE 310 283 283 ILE ILE A . n A 1 311 VAL 311 284 284 VAL VAL A . n A 1 312 ARG 312 285 285 ARG ARG A . n A 1 313 ARG 313 286 286 ARG ARG A . n A 1 314 ASN 314 287 287 ASN ASN A . n A 1 315 ILE 315 288 288 ILE ILE A . n A 1 316 THR 316 289 289 THR THR A . n A 1 317 GLY 317 290 290 GLY GLY A . n A 1 318 LYS 318 291 291 LYS LYS A . n A 1 319 ILE 319 292 292 ILE ILE A . n A 1 320 TRP 320 293 293 TRP TRP A . n A 1 321 LEU 321 294 294 LEU LEU A . n A 1 322 ALA 322 295 295 ALA ALA A . n A 1 323 SER 323 296 296 SER SER A . n A 1 324 GLU 324 297 297 GLU GLU A . n A 1 325 ALA 325 298 298 ALA ALA A . n A 1 326 TRP 326 299 299 TRP TRP A . n A 1 327 ALA 327 300 300 ALA ALA A . n A 1 328 SER 328 301 301 SER SER A . n A 1 329 SER 329 302 302 SER SER A . n A 1 330 SER 330 303 303 SER SER A . n A 1 331 LEU 331 304 304 LEU LEU A . n A 1 332 ILE 332 305 305 ILE ILE A . n A 1 333 ALA 333 306 306 ALA ALA A . n A 1 334 MET 334 307 307 MET MET A . n A 1 335 PRO 335 308 308 PRO PRO A . n A 1 336 GLN 336 309 309 GLN GLN A . n A 1 337 TYR 337 310 310 TYR TYR A . n A 1 338 PHE 338 311 311 PHE PHE A . n A 1 339 HIS 339 312 312 HIS HIS A . n A 1 340 VAL 340 313 313 VAL VAL A . n A 1 341 VAL 341 314 314 VAL VAL A . n A 1 342 GLY 342 315 315 GLY GLY A . n A 1 343 GLY 343 316 316 GLY GLY A . n A 1 344 THR 344 317 317 THR THR A . n A 1 345 ILE 345 318 318 ILE ILE A . n A 1 346 GLY 346 319 319 GLY GLY A . n A 1 347 PHE 347 320 320 PHE PHE A . n A 1 348 ALA 348 321 321 ALA ALA A . n A 1 349 LEU 349 322 322 LEU LEU A . n A 1 350 LYS 350 323 323 LYS LYS A . n A 1 351 ALA 351 324 324 ALA ALA A . n A 1 352 GLY 352 325 325 GLY GLY A . n A 1 353 GLN 353 326 326 GLN GLN A . n A 1 354 ILE 354 327 327 ILE ILE A . n A 1 355 PRO 355 328 328 PRO PRO A . n A 1 356 GLY 356 329 329 GLY GLY A . n A 1 357 PHE 357 330 330 PHE PHE A . n A 1 358 ARG 358 331 331 ARG ARG A . n A 1 359 GLU 359 332 332 GLU GLU A . n A 1 360 PHE 360 333 333 PHE PHE A . n A 1 361 LEU 361 334 334 LEU LEU A . n A 1 362 LYS 362 335 335 LYS LYS A . n A 1 363 LYS 363 336 336 LYS LYS A . n A 1 364 VAL 364 337 337 VAL VAL A . n A 1 365 HIS 365 338 338 HIS HIS A . n A 1 366 PRO 366 339 339 PRO PRO A . n A 1 367 ARG 367 340 340 ARG ARG A . n A 1 368 LYS 368 341 341 LYS LYS A . n A 1 369 SER 369 342 342 SER SER A . n A 1 370 VAL 370 343 343 VAL VAL A . n A 1 371 HIS 371 344 344 HIS HIS A . n A 1 372 ASN 372 345 345 ASN ASN A . n A 1 373 GLY 373 346 346 GLY GLY A . n A 1 374 PHE 374 347 347 PHE PHE A . n A 1 375 ALA 375 348 348 ALA ALA A . n A 1 376 LYS 376 349 349 LYS LYS A . n A 1 377 GLU 377 350 350 GLU GLU A . n A 1 378 PHE 378 351 351 PHE PHE A . n A 1 379 TRP 379 352 352 TRP TRP A . n A 1 380 GLU 380 353 353 GLU GLU A . n A 1 381 GLU 381 354 354 GLU GLU A . n A 1 382 THR 382 355 355 THR THR A . n A 1 383 PHE 383 356 356 PHE PHE A . n A 1 384 ASN 384 357 357 ASN ASN A . n A 1 385 CYS 385 358 358 CYS CYS A . n A 1 386 HIS 386 359 359 HIS HIS A . n A 1 387 LEU 387 360 360 LEU LEU A . n A 1 388 GLN 388 361 ? ? ? A . n A 1 389 GLU 389 362 ? ? ? A . n A 1 390 GLY 390 363 ? ? ? A . n A 1 391 ALA 391 364 ? ? ? A . n A 1 392 LYS 392 365 ? ? ? A . n A 1 393 GLY 393 366 ? ? ? A . n A 1 394 PRO 394 367 ? ? ? A . n A 1 395 LEU 395 368 ? ? ? A . n A 1 396 PRO 396 369 ? ? ? A . n A 1 397 VAL 397 370 ? ? ? A . n A 1 398 ASP 398 371 ? ? ? A . n A 1 399 THR 399 372 ? ? ? A . n A 1 400 PHE 400 373 ? ? ? A . n A 1 401 LEU 401 374 ? ? ? A . n A 1 402 ARG 402 375 ? ? ? A . n A 1 403 GLY 403 376 ? ? ? A . n A 1 404 HIS 404 377 ? ? ? A . n A 1 405 GLU 405 378 ? ? ? A . n A 1 406 GLU 406 379 ? ? ? A . n A 1 407 SER 407 380 ? ? ? A . n A 1 408 GLY 408 381 ? ? ? A . n A 1 409 ASP 409 382 ? ? ? A . n A 1 410 ARG 410 383 ? ? ? A . n A 1 411 PHE 411 384 ? ? ? A . n A 1 412 SER 412 385 ? ? ? A . n A 1 413 ASN 413 386 ? ? ? A . n A 1 414 SER 414 387 ? ? ? A . n A 1 415 SER 415 388 ? ? ? A . n A 1 416 THR 416 389 ? ? ? A . n A 1 417 ALA 417 390 ? ? ? A . n A 1 418 PHE 418 391 ? ? ? A . n A 1 419 ARG 419 392 392 ARG ARG A . n A 1 420 PRO 420 393 393 PRO PRO A . n A 1 421 LEU 421 394 394 LEU LEU A . n A 1 422 CYS 422 395 395 CYS CYS A . n A 1 423 THR 423 396 396 THR THR A . n A 1 424 GLY 424 397 397 GLY GLY A . n A 1 425 ASP 425 398 398 ASP ASP A . n A 1 426 GLU 426 399 399 GLU GLU A . n A 1 427 ASN 427 400 400 ASN ASN A . n A 1 428 ILE 428 401 401 ILE ILE A . n A 1 429 SER 429 402 402 SER SER A . n A 1 430 SER 430 403 403 SER SER A . n A 1 431 VAL 431 404 404 VAL VAL A . n A 1 432 GLU 432 405 405 GLU GLU A . n A 1 433 THR 433 406 406 THR THR A . n A 1 434 PRO 434 407 407 PRO PRO A . n A 1 435 TYR 435 408 408 TYR TYR A . n A 1 436 ILE 436 409 409 ILE ILE A . n A 1 437 ASP 437 410 410 ASP ASP A . n A 1 438 TYR 438 411 411 TYR TYR A . n A 1 439 THR 439 412 412 THR THR A . n A 1 440 HIS 440 413 413 HIS HIS A . n A 1 441 LEU 441 414 414 LEU LEU A . n A 1 442 ARG 442 415 415 ARG ARG A . n A 1 443 ILE 443 416 416 ILE ILE A . n A 1 444 SER 444 417 417 SER SER A . n A 1 445 TYR 445 418 418 TYR TYR A . n A 1 446 ASN 446 419 419 ASN ASN A . n A 1 447 VAL 447 420 420 VAL VAL A . n A 1 448 TYR 448 421 421 TYR TYR A . n A 1 449 LEU 449 422 422 LEU LEU A . n A 1 450 ALA 450 423 423 ALA ALA A . n A 1 451 VAL 451 424 424 VAL VAL A . n A 1 452 TYR 452 425 425 TYR TYR A . n A 1 453 SER 453 426 426 SER SER A . n A 1 454 ILE 454 427 427 ILE ILE A . n A 1 455 ALA 455 428 428 ALA ALA A . n A 1 456 HIS 456 429 429 HIS HIS A . n A 1 457 ALA 457 430 430 ALA ALA A . n A 1 458 LEU 458 431 431 LEU LEU A . n A 1 459 GLN 459 432 432 GLN GLN A . n A 1 460 ASP 460 433 433 ASP ASP A . n A 1 461 ILE 461 434 434 ILE ILE A . n A 1 462 TYR 462 435 435 TYR TYR A . n A 1 463 THR 463 436 436 THR THR A . n A 1 464 CYS 464 437 437 CYS CYS A . n A 1 465 LEU 465 438 438 LEU LEU A . n A 1 466 PRO 466 439 439 PRO PRO A . n A 1 467 GLY 467 440 440 GLY GLY A . n A 1 468 ARG 468 441 441 ARG ARG A . n A 1 469 GLY 469 442 442 GLY GLY A . n A 1 470 LEU 470 443 443 LEU LEU A . n A 1 471 PHE 471 444 444 PHE PHE A . n A 1 472 THR 472 445 445 THR THR A . n A 1 473 ASN 473 446 446 ASN ASN A . n A 1 474 GLY 474 447 447 GLY GLY A . n A 1 475 SER 475 448 448 SER SER A . n A 1 476 CYS 476 449 449 CYS CYS A . n A 1 477 ALA 477 450 450 ALA ALA A . n A 1 478 ASP 478 451 451 ASP ASP A . n A 1 479 ILE 479 452 452 ILE ILE A . n A 1 480 LYS 480 453 453 LYS LYS A . n A 1 481 LYS 481 454 454 LYS LYS A . n A 1 482 VAL 482 455 455 VAL VAL A . n A 1 483 GLU 483 456 456 GLU GLU A . n A 1 484 ALA 484 457 457 ALA ALA A . n A 1 485 TRP 485 458 458 TRP TRP A . n A 1 486 GLN 486 459 459 GLN GLN A . n A 1 487 VAL 487 460 460 VAL VAL A . n A 1 488 LEU 488 461 461 LEU LEU A . n A 1 489 LYS 489 462 462 LYS LYS A . n A 1 490 HIS 490 463 463 HIS HIS A . n A 1 491 LEU 491 464 464 LEU LEU A . n A 1 492 ARG 492 465 465 ARG ARG A . n A 1 493 HIS 493 466 466 HIS HIS A . n A 1 494 LEU 494 467 467 LEU LEU A . n A 1 495 ASN 495 468 468 ASN ASN A . n A 1 496 PHE 496 469 469 PHE PHE A . n A 1 497 THR 497 470 470 THR THR A . n A 1 498 ASN 498 471 471 ASN ASN A . n A 1 499 ASN 499 472 472 ASN ASN A . n A 1 500 MET 500 473 473 MET MET A . n A 1 501 GLY 501 474 474 GLY GLY A . n A 1 502 GLU 502 475 475 GLU GLU A . n A 1 503 GLN 503 476 476 GLN GLN A . n A 1 504 VAL 504 477 477 VAL VAL A . n A 1 505 THR 505 478 478 THR THR A . n A 1 506 PHE 506 479 479 PHE PHE A . n A 1 507 ASP 507 480 480 ASP ASP A . n A 1 508 GLU 508 481 481 GLU GLU A . n A 1 509 CSO 509 482 482 CSO CSO A . n A 1 510 GLY 510 483 483 GLY GLY A . n A 1 511 ASP 511 484 484 ASP ASP A . n A 1 512 LEU 512 485 485 LEU LEU A . n A 1 513 VAL 513 486 486 VAL VAL A . n A 1 514 GLY 514 487 487 GLY GLY A . n A 1 515 ASN 515 488 488 ASN ASN A . n A 1 516 TYR 516 489 489 TYR TYR A . n A 1 517 SER 517 490 490 SER SER A . n A 1 518 ILE 518 491 491 ILE ILE A . n A 1 519 ILE 519 492 492 ILE ILE A . n A 1 520 ASN 520 493 493 ASN ASN A . n A 1 521 TRP 521 494 494 TRP TRP A . n A 1 522 HIS 522 495 495 HIS HIS A . n A 1 523 LEU 523 496 496 LEU LEU A . n A 1 524 SER 524 497 497 SER SER A . n A 1 525 PRO 525 498 498 PRO PRO A . n A 1 526 GLU 526 499 499 GLU GLU A . n A 1 527 ASP 527 500 500 ASP ASP A . n A 1 528 GLY 528 501 501 GLY GLY A . n A 1 529 SER 529 502 502 SER SER A . n A 1 530 ILE 530 503 503 ILE ILE A . n A 1 531 VAL 531 504 504 VAL VAL A . n A 1 532 PHE 532 505 505 PHE PHE A . n A 1 533 LYS 533 506 506 LYS LYS A . n A 1 534 GLU 534 507 507 GLU GLU A . n A 1 535 VAL 535 508 508 VAL VAL A . n A 1 536 GLY 536 509 509 GLY GLY A . n A 1 537 TYR 537 510 510 TYR TYR A . n A 1 538 TYR 538 511 511 TYR TYR A . n A 1 539 ASN 539 512 512 ASN ASN A . n A 1 540 VAL 540 513 513 VAL VAL A . n A 1 541 TYR 541 514 514 TYR TYR A . n A 1 542 ALA 542 515 515 ALA ALA A . n A 1 543 LYS 543 516 516 LYS LYS A . n A 1 544 LYS 544 517 517 LYS LYS A . n A 1 545 GLY 545 518 518 GLY GLY A . n A 1 546 GLU 546 519 519 GLU GLU A . n A 1 547 ARG 547 520 520 ARG ARG A . n A 1 548 LEU 548 521 521 LEU LEU A . n A 1 549 PHE 549 522 522 PHE PHE A . n A 1 550 ILE 550 523 523 ILE ILE A . n A 1 551 ASN 551 524 524 ASN ASN A . n A 1 552 GLU 552 525 525 GLU GLU A . n A 1 553 GLU 553 526 526 GLU GLU A . n A 1 554 LYS 554 527 527 LYS LYS A . n A 1 555 ILE 555 528 528 ILE ILE A . n A 1 556 LEU 556 529 529 LEU LEU A . n A 1 557 TRP 557 530 530 TRP TRP A . n A 1 558 SER 558 531 531 SER SER A . n A 1 559 GLY 559 532 532 GLY GLY A . n A 1 560 PHE 560 533 533 PHE PHE A . n A 1 561 SER 561 534 534 SER SER A . n A 1 562 ARG 562 535 535 ARG ARG A . n A 1 563 GLU 563 536 536 GLU GLU A . n A 1 564 VAL 564 537 537 VAL VAL A . n A 1 565 PRO 565 538 538 PRO PRO A . n A 1 566 PHE 566 539 539 PHE PHE A . n A 1 567 SER 567 540 ? ? ? A . n A 1 568 ASN 568 541 ? ? ? A . n B 1 1 MET 1 -26 ? ? ? B . n B 1 2 ARG 2 -25 ? ? ? B . n B 1 3 LEU 3 -24 ? ? ? B . n B 1 4 LEU 4 -23 ? ? ? B . n B 1 5 THR 5 -22 ? ? ? B . n B 1 6 ALA 6 -21 ? ? ? B . n B 1 7 LEU 7 -20 ? ? ? B . n B 1 8 PHE 8 -19 ? ? ? B . n B 1 9 ALA 9 -18 ? ? ? B . n B 1 10 TYR 10 -17 ? ? ? B . n B 1 11 PHE 11 -16 ? ? ? B . n B 1 12 ILE 12 -15 ? ? ? B . n B 1 13 VAL 13 -14 ? ? ? B . n B 1 14 ALA 14 -13 ? ? ? B . n B 1 15 LEU 15 -12 ? ? ? B . n B 1 16 ILE 16 -11 ? ? ? B . n B 1 17 LEU 17 -10 ? ? ? B . n B 1 18 ALA 18 -9 ? ? ? B . n B 1 19 PHE 19 -8 ? ? ? B . n B 1 20 SER 20 -7 ? ? ? B . n B 1 21 VAL 21 -6 ? ? ? B . n B 1 22 SER 22 -5 ? ? ? B . n B 1 23 ALA 23 -4 ? ? ? B . n B 1 24 LYS 24 -3 ? ? ? B . n B 1 25 SER 25 -2 ? ? ? B . n B 1 26 MET 26 -1 ? ? ? B . n B 1 27 HIS 27 0 ? ? ? B . n B 1 28 HIS 28 1 ? ? ? B . n B 1 29 HIS 29 2 ? ? ? B . n B 1 30 HIS 30 3 ? ? ? B . n B 1 31 HIS 31 4 ? ? ? B . n B 1 32 HIS 32 5 ? ? ? B . n B 1 33 HIS 33 6 ? ? ? B . n B 1 34 HIS 34 7 ? ? ? B . n B 1 35 SER 35 8 ? ? ? B . n B 1 36 ALA 36 9 ? ? ? B . n B 1 37 TRP 37 10 ? ? ? B . n B 1 38 SER 38 11 ? ? ? B . n B 1 39 HIS 39 12 ? ? ? B . n B 1 40 PRO 40 13 ? ? ? B . n B 1 41 GLN 41 14 ? ? ? B . n B 1 42 PHE 42 15 ? ? ? B . n B 1 43 GLU 43 16 ? ? ? B . n B 1 44 LYS 44 17 ? ? ? B . n B 1 45 GLU 45 18 ? ? ? B . n B 1 46 PHE 46 19 ? ? ? B . n B 1 47 TYR 47 20 ? ? ? B . n B 1 48 GLY 48 21 21 GLY GLY B . n B 1 49 PRO 49 22 22 PRO PRO B . n B 1 50 ASP 50 23 23 ASP ASP B . n B 1 51 GLN 51 24 24 GLN GLN B . n B 1 52 ARG 52 25 25 ARG ARG B . n B 1 53 ALA 53 26 26 ALA ALA B . n B 1 54 GLN 54 27 27 GLN GLN B . n B 1 55 LYS 55 28 28 LYS LYS B . n B 1 56 LYS 56 29 29 LYS LYS B . n B 1 57 GLY 57 30 30 GLY GLY B . n B 1 58 ASP 58 31 31 ASP ASP B . n B 1 59 ILE 59 32 32 ILE ILE B . n B 1 60 ILE 60 33 33 ILE ILE B . n B 1 61 LEU 61 34 34 LEU LEU B . n B 1 62 GLY 62 35 35 GLY GLY B . n B 1 63 GLY 63 36 36 GLY GLY B . n B 1 64 LEU 64 37 37 LEU LEU B . n B 1 65 PHE 65 38 38 PHE PHE B . n B 1 66 PRO 66 39 39 PRO PRO B . n B 1 67 ILE 67 40 40 ILE ILE B . n B 1 68 HIS 68 41 41 HIS HIS B . n B 1 69 PHE 69 42 42 PHE PHE B . n B 1 70 GLY 70 43 43 GLY GLY B . n B 1 71 VAL 71 44 44 VAL VAL B . n B 1 72 ALA 72 45 45 ALA ALA B . n B 1 73 ALA 73 46 46 ALA ALA B . n B 1 74 LYS 74 47 47 LYS LYS B . n B 1 75 ASP 75 48 48 ASP ASP B . n B 1 76 GLN 76 49 49 GLN GLN B . n B 1 77 ASP 77 50 50 ASP ASP B . n B 1 78 LEU 78 51 51 LEU LEU B . n B 1 79 LYS 79 52 52 LYS LYS B . n B 1 80 SER 80 53 53 SER SER B . n B 1 81 ARG 81 54 54 ARG ARG B . n B 1 82 PRO 82 55 55 PRO PRO B . n B 1 83 GLU 83 56 56 GLU GLU B . n B 1 84 SER 84 57 57 SER SER B . n B 1 85 VAL 85 58 58 VAL VAL B . n B 1 86 GLU 86 59 59 GLU GLU B . n B 1 87 CYS 87 60 60 CYS CYS B . n B 1 88 ILE 88 61 61 ILE ILE B . n B 1 89 ARG 89 62 62 ARG ARG B . n B 1 90 TYR 90 63 63 TYR TYR B . n B 1 91 ASN 91 64 64 ASN ASN B . n B 1 92 PHE 92 65 65 PHE PHE B . n B 1 93 ARG 93 66 66 ARG ARG B . n B 1 94 GLY 94 67 67 GLY GLY B . n B 1 95 PHE 95 68 68 PHE PHE B . n B 1 96 ARG 96 69 69 ARG ARG B . n B 1 97 TRP 97 70 70 TRP TRP B . n B 1 98 LEU 98 71 71 LEU LEU B . n B 1 99 GLN 99 72 72 GLN GLN B . n B 1 100 ALA 100 73 73 ALA ALA B . n B 1 101 MET 101 74 74 MET MET B . n B 1 102 ILE 102 75 75 ILE ILE B . n B 1 103 PHE 103 76 76 PHE PHE B . n B 1 104 ALA 104 77 77 ALA ALA B . n B 1 105 ILE 105 78 78 ILE ILE B . n B 1 106 GLU 106 79 79 GLU GLU B . n B 1 107 GLU 107 80 80 GLU GLU B . n B 1 108 ILE 108 81 81 ILE ILE B . n B 1 109 ASN 109 82 82 ASN ASN B . n B 1 110 SER 110 83 83 SER SER B . n B 1 111 SER 111 84 84 SER SER B . n B 1 112 PRO 112 85 85 PRO PRO B . n B 1 113 ALA 113 86 86 ALA ALA B . n B 1 114 LEU 114 87 87 LEU LEU B . n B 1 115 LEU 115 88 88 LEU LEU B . n B 1 116 PRO 116 89 89 PRO PRO B . n B 1 117 ASN 117 90 90 ASN ASN B . n B 1 118 LEU 118 91 91 LEU LEU B . n B 1 119 THR 119 92 92 THR THR B . n B 1 120 LEU 120 93 93 LEU LEU B . n B 1 121 GLY 121 94 94 GLY GLY B . n B 1 122 TYR 122 95 95 TYR TYR B . n B 1 123 ARG 123 96 96 ARG ARG B . n B 1 124 ILE 124 97 97 ILE ILE B . n B 1 125 PHE 125 98 98 PHE PHE B . n B 1 126 ASP 126 99 99 ASP ASP B . n B 1 127 THR 127 100 100 THR THR B . n B 1 128 CYS 128 101 101 CYS CYS B . n B 1 129 ASN 129 102 102 ASN ASN B . n B 1 130 THR 130 103 103 THR THR B . n B 1 131 VAL 131 104 104 VAL VAL B . n B 1 132 SER 132 105 105 SER SER B . n B 1 133 LYS 133 106 106 LYS LYS B . n B 1 134 ALA 134 107 107 ALA ALA B . n B 1 135 LEU 135 108 108 LEU LEU B . n B 1 136 GLU 136 109 109 GLU GLU B . n B 1 137 ALA 137 110 110 ALA ALA B . n B 1 138 THR 138 111 111 THR THR B . n B 1 139 LEU 139 112 112 LEU LEU B . n B 1 140 SER 140 113 113 SER SER B . n B 1 141 PHE 141 114 114 PHE PHE B . n B 1 142 VAL 142 115 115 VAL VAL B . n B 1 143 ALA 143 116 116 ALA ALA B . n B 1 144 GLN 144 117 117 GLN GLN B . n B 1 145 ASN 145 118 118 ASN ASN B . n B 1 146 LYS 146 119 119 LYS LYS B . n B 1 147 ILE 147 120 120 ILE ILE B . n B 1 148 ASP 148 121 121 ASP ASP B . n B 1 149 SER 149 122 ? ? ? B . n B 1 150 LEU 150 123 ? ? ? B . n B 1 151 ASN 151 124 ? ? ? B . n B 1 152 LEU 152 125 ? ? ? B . n B 1 153 ASP 153 126 ? ? ? B . n B 1 154 GLU 154 127 ? ? ? B . n B 1 155 PHE 155 128 ? ? ? B . n B 1 156 CYS 156 129 ? ? ? B . n B 1 157 ASN 157 130 ? ? ? B . n B 1 158 CYS 158 131 ? ? ? B . n B 1 159 SER 159 132 ? ? ? B . n B 1 160 GLU 160 133 ? ? ? B . n B 1 161 HIS 161 134 ? ? ? B . n B 1 162 ILE 162 135 ? ? ? B . n B 1 163 PRO 163 136 ? ? ? B . n B 1 164 SER 164 137 137 SER SER B . n B 1 165 THR 165 138 138 THR THR B . n B 1 166 ILE 166 139 139 ILE ILE B . n B 1 167 ALA 167 140 140 ALA ALA B . n B 1 168 VAL 168 141 141 VAL VAL B . n B 1 169 VAL 169 142 142 VAL VAL B . n B 1 170 GLY 170 143 143 GLY GLY B . n B 1 171 ALA 171 144 144 ALA ALA B . n B 1 172 THR 172 145 145 THR THR B . n B 1 173 GLY 173 146 146 GLY GLY B . n B 1 174 SER 174 147 147 SER SER B . n B 1 175 GLY 175 148 148 GLY GLY B . n B 1 176 VAL 176 149 149 VAL VAL B . n B 1 177 SER 177 150 150 SER SER B . n B 1 178 THR 178 151 151 THR THR B . n B 1 179 ALA 179 152 152 ALA ALA B . n B 1 180 VAL 180 153 153 VAL VAL B . n B 1 181 ALA 181 154 154 ALA ALA B . n B 1 182 ASN 182 155 155 ASN ASN B . n B 1 183 LEU 183 156 156 LEU LEU B . n B 1 184 LEU 184 157 157 LEU LEU B . n B 1 185 GLY 185 158 158 GLY GLY B . n B 1 186 LEU 186 159 159 LEU LEU B . n B 1 187 PHE 187 160 160 PHE PHE B . n B 1 188 TYR 188 161 161 TYR TYR B . n B 1 189 ILE 189 162 162 ILE ILE B . n B 1 190 PRO 190 163 163 PRO PRO B . n B 1 191 GLN 191 164 164 GLN GLN B . n B 1 192 VAL 192 165 165 VAL VAL B . n B 1 193 SER 193 166 166 SER SER B . n B 1 194 TYR 194 167 167 TYR TYR B . n B 1 195 ALA 195 168 168 ALA ALA B . n B 1 196 SER 196 169 169 SER SER B . n B 1 197 SER 197 170 170 SER SER B . n B 1 198 SER 198 171 171 SER SER B . n B 1 199 ARG 199 172 172 ARG ARG B . n B 1 200 LEU 200 173 173 LEU LEU B . n B 1 201 LEU 201 174 174 LEU LEU B . n B 1 202 SER 202 175 175 SER SER B . n B 1 203 ASN 203 176 176 ASN ASN B . n B 1 204 LYS 204 177 177 LYS LYS B . n B 1 205 ASN 205 178 178 ASN ASN B . n B 1 206 GLN 206 179 179 GLN GLN B . n B 1 207 PHE 207 180 180 PHE PHE B . n B 1 208 LYS 208 181 181 LYS LYS B . n B 1 209 SER 209 182 182 SER SER B . n B 1 210 PHE 210 183 183 PHE PHE B . n B 1 211 LEU 211 184 184 LEU LEU B . n B 1 212 ARG 212 185 185 ARG ARG B . n B 1 213 THR 213 186 186 THR THR B . n B 1 214 ILE 214 187 187 ILE ILE B . n B 1 215 PRO 215 188 188 PRO PRO B . n B 1 216 ASN 216 189 189 ASN ASN B . n B 1 217 ASP 217 190 190 ASP ASP B . n B 1 218 GLU 218 191 191 GLU GLU B . n B 1 219 HIS 219 192 192 HIS HIS B . n B 1 220 GLN 220 193 193 GLN GLN B . n B 1 221 ALA 221 194 194 ALA ALA B . n B 1 222 THR 222 195 195 THR THR B . n B 1 223 ALA 223 196 196 ALA ALA B . n B 1 224 MET 224 197 197 MET MET B . n B 1 225 ALA 225 198 198 ALA ALA B . n B 1 226 ASP 226 199 199 ASP ASP B . n B 1 227 ILE 227 200 200 ILE ILE B . n B 1 228 ILE 228 201 201 ILE ILE B . n B 1 229 GLU 229 202 202 GLU GLU B . n B 1 230 TYR 230 203 203 TYR TYR B . n B 1 231 PHE 231 204 204 PHE PHE B . n B 1 232 ARG 232 205 205 ARG ARG B . n B 1 233 TRP 233 206 206 TRP TRP B . n B 1 234 ASN 234 207 207 ASN ASN B . n B 1 235 TRP 235 208 208 TRP TRP B . n B 1 236 VAL 236 209 209 VAL VAL B . n B 1 237 GLY 237 210 210 GLY GLY B . n B 1 238 THR 238 211 211 THR THR B . n B 1 239 ILE 239 212 212 ILE ILE B . n B 1 240 ALA 240 213 213 ALA ALA B . n B 1 241 ALA 241 214 214 ALA ALA B . n B 1 242 ASP 242 215 215 ASP ASP B . n B 1 243 ASP 243 216 216 ASP ASP B . n B 1 244 ASP 244 217 217 ASP ASP B . n B 1 245 TYR 245 218 218 TYR TYR B . n B 1 246 GLY 246 219 219 GLY GLY B . n B 1 247 ARG 247 220 220 ARG ARG B . n B 1 248 PRO 248 221 221 PRO PRO B . n B 1 249 GLY 249 222 222 GLY GLY B . n B 1 250 ILE 250 223 223 ILE ILE B . n B 1 251 GLU 251 224 224 GLU GLU B . n B 1 252 LYS 252 225 225 LYS LYS B . n B 1 253 PHE 253 226 226 PHE PHE B . n B 1 254 ARG 254 227 227 ARG ARG B . n B 1 255 GLU 255 228 228 GLU GLU B . n B 1 256 GLU 256 229 229 GLU GLU B . n B 1 257 ALA 257 230 230 ALA ALA B . n B 1 258 GLU 258 231 231 GLU GLU B . n B 1 259 GLU 259 232 232 GLU GLU B . n B 1 260 ARG 260 233 233 ARG ARG B . n B 1 261 ASP 261 234 234 ASP ASP B . n B 1 262 ILE 262 235 235 ILE ILE B . n B 1 263 CSO 263 236 236 CSO CSO B . n B 1 264 ILE 264 237 237 ILE ILE B . n B 1 265 ASP 265 238 238 ASP ASP B . n B 1 266 PHE 266 239 239 PHE PHE B . n B 1 267 SER 267 240 240 SER SER B . n B 1 268 GLU 268 241 241 GLU GLU B . n B 1 269 LEU 269 242 242 LEU LEU B . n B 1 270 ILE 270 243 243 ILE ILE B . n B 1 271 SER 271 244 244 SER SER B . n B 1 272 GLN 272 245 245 GLN GLN B . n B 1 273 TYR 273 246 246 TYR TYR B . n B 1 274 SER 274 247 247 SER SER B . n B 1 275 ASP 275 248 248 ASP ASP B . n B 1 276 GLU 276 249 249 GLU GLU B . n B 1 277 GLU 277 250 250 GLU GLU B . n B 1 278 GLU 278 251 251 GLU GLU B . n B 1 279 ILE 279 252 252 ILE ILE B . n B 1 280 GLN 280 253 253 GLN GLN B . n B 1 281 HIS 281 254 254 HIS HIS B . n B 1 282 VAL 282 255 255 VAL VAL B . n B 1 283 VAL 283 256 256 VAL VAL B . n B 1 284 GLU 284 257 257 GLU GLU B . n B 1 285 VAL 285 258 258 VAL VAL B . n B 1 286 ILE 286 259 259 ILE ILE B . n B 1 287 GLN 287 260 260 GLN GLN B . n B 1 288 ASN 288 261 261 ASN ASN B . n B 1 289 SER 289 262 262 SER SER B . n B 1 290 THR 290 263 263 THR THR B . n B 1 291 ALA 291 264 264 ALA ALA B . n B 1 292 LYS 292 265 265 LYS LYS B . n B 1 293 VAL 293 266 266 VAL VAL B . n B 1 294 ILE 294 267 267 ILE ILE B . n B 1 295 VAL 295 268 268 VAL VAL B . n B 1 296 VAL 296 269 269 VAL VAL B . n B 1 297 PHE 297 270 270 PHE PHE B . n B 1 298 SER 298 271 271 SER SER B . n B 1 299 SER 299 272 272 SER SER B . n B 1 300 GLY 300 273 273 GLY GLY B . n B 1 301 PRO 301 274 274 PRO PRO B . n B 1 302 ASP 302 275 275 ASP ASP B . n B 1 303 LEU 303 276 276 LEU LEU B . n B 1 304 GLU 304 277 277 GLU GLU B . n B 1 305 PRO 305 278 278 PRO PRO B . n B 1 306 LEU 306 279 279 LEU LEU B . n B 1 307 ILE 307 280 280 ILE ILE B . n B 1 308 LYS 308 281 281 LYS LYS B . n B 1 309 GLU 309 282 282 GLU GLU B . n B 1 310 ILE 310 283 283 ILE ILE B . n B 1 311 VAL 311 284 284 VAL VAL B . n B 1 312 ARG 312 285 285 ARG ARG B . n B 1 313 ARG 313 286 286 ARG ARG B . n B 1 314 ASN 314 287 287 ASN ASN B . n B 1 315 ILE 315 288 288 ILE ILE B . n B 1 316 THR 316 289 289 THR THR B . n B 1 317 GLY 317 290 290 GLY GLY B . n B 1 318 LYS 318 291 291 LYS LYS B . n B 1 319 ILE 319 292 292 ILE ILE B . n B 1 320 TRP 320 293 293 TRP TRP B . n B 1 321 LEU 321 294 294 LEU LEU B . n B 1 322 ALA 322 295 295 ALA ALA B . n B 1 323 SER 323 296 296 SER SER B . n B 1 324 GLU 324 297 297 GLU GLU B . n B 1 325 ALA 325 298 298 ALA ALA B . n B 1 326 TRP 326 299 299 TRP TRP B . n B 1 327 ALA 327 300 300 ALA ALA B . n B 1 328 SER 328 301 301 SER SER B . n B 1 329 SER 329 302 302 SER SER B . n B 1 330 SER 330 303 303 SER SER B . n B 1 331 LEU 331 304 304 LEU LEU B . n B 1 332 ILE 332 305 305 ILE ILE B . n B 1 333 ALA 333 306 306 ALA ALA B . n B 1 334 MET 334 307 307 MET MET B . n B 1 335 PRO 335 308 308 PRO PRO B . n B 1 336 GLN 336 309 309 GLN GLN B . n B 1 337 TYR 337 310 310 TYR TYR B . n B 1 338 PHE 338 311 311 PHE PHE B . n B 1 339 HIS 339 312 312 HIS HIS B . n B 1 340 VAL 340 313 313 VAL VAL B . n B 1 341 VAL 341 314 314 VAL VAL B . n B 1 342 GLY 342 315 315 GLY GLY B . n B 1 343 GLY 343 316 316 GLY GLY B . n B 1 344 THR 344 317 317 THR THR B . n B 1 345 ILE 345 318 318 ILE ILE B . n B 1 346 GLY 346 319 319 GLY GLY B . n B 1 347 PHE 347 320 320 PHE PHE B . n B 1 348 ALA 348 321 321 ALA ALA B . n B 1 349 LEU 349 322 322 LEU LEU B . n B 1 350 LYS 350 323 323 LYS LYS B . n B 1 351 ALA 351 324 324 ALA ALA B . n B 1 352 GLY 352 325 325 GLY GLY B . n B 1 353 GLN 353 326 326 GLN GLN B . n B 1 354 ILE 354 327 327 ILE ILE B . n B 1 355 PRO 355 328 328 PRO PRO B . n B 1 356 GLY 356 329 329 GLY GLY B . n B 1 357 PHE 357 330 330 PHE PHE B . n B 1 358 ARG 358 331 331 ARG ARG B . n B 1 359 GLU 359 332 332 GLU GLU B . n B 1 360 PHE 360 333 333 PHE PHE B . n B 1 361 LEU 361 334 334 LEU LEU B . n B 1 362 LYS 362 335 335 LYS LYS B . n B 1 363 LYS 363 336 336 LYS LYS B . n B 1 364 VAL 364 337 337 VAL VAL B . n B 1 365 HIS 365 338 338 HIS HIS B . n B 1 366 PRO 366 339 339 PRO PRO B . n B 1 367 ARG 367 340 340 ARG ARG B . n B 1 368 LYS 368 341 341 LYS LYS B . n B 1 369 SER 369 342 342 SER SER B . n B 1 370 VAL 370 343 343 VAL VAL B . n B 1 371 HIS 371 344 344 HIS HIS B . n B 1 372 ASN 372 345 345 ASN ASN B . n B 1 373 GLY 373 346 346 GLY GLY B . n B 1 374 PHE 374 347 347 PHE PHE B . n B 1 375 ALA 375 348 348 ALA ALA B . n B 1 376 LYS 376 349 349 LYS LYS B . n B 1 377 GLU 377 350 350 GLU GLU B . n B 1 378 PHE 378 351 351 PHE PHE B . n B 1 379 TRP 379 352 352 TRP TRP B . n B 1 380 GLU 380 353 353 GLU GLU B . n B 1 381 GLU 381 354 354 GLU GLU B . n B 1 382 THR 382 355 355 THR THR B . n B 1 383 PHE 383 356 356 PHE PHE B . n B 1 384 ASN 384 357 357 ASN ASN B . n B 1 385 CYS 385 358 358 CYS CYS B . n B 1 386 HIS 386 359 359 HIS HIS B . n B 1 387 LEU 387 360 360 LEU LEU B . n B 1 388 GLN 388 361 361 GLN GLN B . n B 1 389 GLU 389 362 ? ? ? B . n B 1 390 GLY 390 363 ? ? ? B . n B 1 391 ALA 391 364 ? ? ? B . n B 1 392 LYS 392 365 ? ? ? B . n B 1 393 GLY 393 366 ? ? ? B . n B 1 394 PRO 394 367 ? ? ? B . n B 1 395 LEU 395 368 ? ? ? B . n B 1 396 PRO 396 369 ? ? ? B . n B 1 397 VAL 397 370 ? ? ? B . n B 1 398 ASP 398 371 ? ? ? B . n B 1 399 THR 399 372 ? ? ? B . n B 1 400 PHE 400 373 ? ? ? B . n B 1 401 LEU 401 374 ? ? ? B . n B 1 402 ARG 402 375 ? ? ? B . n B 1 403 GLY 403 376 ? ? ? B . n B 1 404 HIS 404 377 ? ? ? B . n B 1 405 GLU 405 378 ? ? ? B . n B 1 406 GLU 406 379 ? ? ? B . n B 1 407 SER 407 380 ? ? ? B . n B 1 408 GLY 408 381 ? ? ? B . n B 1 409 ASP 409 382 ? ? ? B . n B 1 410 ARG 410 383 ? ? ? B . n B 1 411 PHE 411 384 ? ? ? B . n B 1 412 SER 412 385 ? ? ? B . n B 1 413 ASN 413 386 ? ? ? B . n B 1 414 SER 414 387 ? ? ? B . n B 1 415 SER 415 388 ? ? ? B . n B 1 416 THR 416 389 ? ? ? B . n B 1 417 ALA 417 390 ? ? ? B . n B 1 418 PHE 418 391 391 PHE PHE B . n B 1 419 ARG 419 392 392 ARG ARG B . n B 1 420 PRO 420 393 393 PRO PRO B . n B 1 421 LEU 421 394 394 LEU LEU B . n B 1 422 CYS 422 395 395 CYS CYS B . n B 1 423 THR 423 396 396 THR THR B . n B 1 424 GLY 424 397 397 GLY GLY B . n B 1 425 ASP 425 398 398 ASP ASP B . n B 1 426 GLU 426 399 399 GLU GLU B . n B 1 427 ASN 427 400 400 ASN ASN B . n B 1 428 ILE 428 401 401 ILE ILE B . n B 1 429 SER 429 402 402 SER SER B . n B 1 430 SER 430 403 403 SER SER B . n B 1 431 VAL 431 404 404 VAL VAL B . n B 1 432 GLU 432 405 405 GLU GLU B . n B 1 433 THR 433 406 406 THR THR B . n B 1 434 PRO 434 407 407 PRO PRO B . n B 1 435 TYR 435 408 408 TYR TYR B . n B 1 436 ILE 436 409 409 ILE ILE B . n B 1 437 ASP 437 410 410 ASP ASP B . n B 1 438 TYR 438 411 411 TYR TYR B . n B 1 439 THR 439 412 412 THR THR B . n B 1 440 HIS 440 413 413 HIS HIS B . n B 1 441 LEU 441 414 414 LEU LEU B . n B 1 442 ARG 442 415 415 ARG ARG B . n B 1 443 ILE 443 416 416 ILE ILE B . n B 1 444 SER 444 417 417 SER SER B . n B 1 445 TYR 445 418 418 TYR TYR B . n B 1 446 ASN 446 419 419 ASN ASN B . n B 1 447 VAL 447 420 420 VAL VAL B . n B 1 448 TYR 448 421 421 TYR TYR B . n B 1 449 LEU 449 422 422 LEU LEU B . n B 1 450 ALA 450 423 423 ALA ALA B . n B 1 451 VAL 451 424 424 VAL VAL B . n B 1 452 TYR 452 425 425 TYR TYR B . n B 1 453 SER 453 426 426 SER SER B . n B 1 454 ILE 454 427 427 ILE ILE B . n B 1 455 ALA 455 428 428 ALA ALA B . n B 1 456 HIS 456 429 429 HIS HIS B . n B 1 457 ALA 457 430 430 ALA ALA B . n B 1 458 LEU 458 431 431 LEU LEU B . n B 1 459 GLN 459 432 432 GLN GLN B . n B 1 460 ASP 460 433 433 ASP ASP B . n B 1 461 ILE 461 434 434 ILE ILE B . n B 1 462 TYR 462 435 435 TYR TYR B . n B 1 463 THR 463 436 436 THR THR B . n B 1 464 CYS 464 437 437 CYS CYS B . n B 1 465 LEU 465 438 438 LEU LEU B . n B 1 466 PRO 466 439 439 PRO PRO B . n B 1 467 GLY 467 440 440 GLY GLY B . n B 1 468 ARG 468 441 441 ARG ARG B . n B 1 469 GLY 469 442 442 GLY GLY B . n B 1 470 LEU 470 443 443 LEU LEU B . n B 1 471 PHE 471 444 444 PHE PHE B . n B 1 472 THR 472 445 445 THR THR B . n B 1 473 ASN 473 446 446 ASN ASN B . n B 1 474 GLY 474 447 447 GLY GLY B . n B 1 475 SER 475 448 448 SER SER B . n B 1 476 CYS 476 449 449 CYS CYS B . n B 1 477 ALA 477 450 450 ALA ALA B . n B 1 478 ASP 478 451 451 ASP ASP B . n B 1 479 ILE 479 452 452 ILE ILE B . n B 1 480 LYS 480 453 453 LYS LYS B . n B 1 481 LYS 481 454 454 LYS LYS B . n B 1 482 VAL 482 455 455 VAL VAL B . n B 1 483 GLU 483 456 456 GLU GLU B . n B 1 484 ALA 484 457 457 ALA ALA B . n B 1 485 TRP 485 458 458 TRP TRP B . n B 1 486 GLN 486 459 459 GLN GLN B . n B 1 487 VAL 487 460 460 VAL VAL B . n B 1 488 LEU 488 461 461 LEU LEU B . n B 1 489 LYS 489 462 462 LYS LYS B . n B 1 490 HIS 490 463 463 HIS HIS B . n B 1 491 LEU 491 464 464 LEU LEU B . n B 1 492 ARG 492 465 465 ARG ARG B . n B 1 493 HIS 493 466 466 HIS HIS B . n B 1 494 LEU 494 467 467 LEU LEU B . n B 1 495 ASN 495 468 468 ASN ASN B . n B 1 496 PHE 496 469 469 PHE PHE B . n B 1 497 THR 497 470 470 THR THR B . n B 1 498 ASN 498 471 471 ASN ASN B . n B 1 499 ASN 499 472 472 ASN ASN B . n B 1 500 MET 500 473 473 MET MET B . n B 1 501 GLY 501 474 474 GLY GLY B . n B 1 502 GLU 502 475 475 GLU GLU B . n B 1 503 GLN 503 476 476 GLN GLN B . n B 1 504 VAL 504 477 477 VAL VAL B . n B 1 505 THR 505 478 478 THR THR B . n B 1 506 PHE 506 479 479 PHE PHE B . n B 1 507 ASP 507 480 480 ASP ASP B . n B 1 508 GLU 508 481 481 GLU GLU B . n B 1 509 CSO 509 482 482 CSO CSO B . n B 1 510 GLY 510 483 483 GLY GLY B . n B 1 511 ASP 511 484 484 ASP ASP B . n B 1 512 LEU 512 485 485 LEU LEU B . n B 1 513 VAL 513 486 486 VAL VAL B . n B 1 514 GLY 514 487 487 GLY GLY B . n B 1 515 ASN 515 488 488 ASN ASN B . n B 1 516 TYR 516 489 489 TYR TYR B . n B 1 517 SER 517 490 490 SER SER B . n B 1 518 ILE 518 491 491 ILE ILE B . n B 1 519 ILE 519 492 492 ILE ILE B . n B 1 520 ASN 520 493 493 ASN ASN B . n B 1 521 TRP 521 494 494 TRP TRP B . n B 1 522 HIS 522 495 495 HIS HIS B . n B 1 523 LEU 523 496 496 LEU LEU B . n B 1 524 SER 524 497 497 SER SER B . n B 1 525 PRO 525 498 498 PRO PRO B . n B 1 526 GLU 526 499 499 GLU GLU B . n B 1 527 ASP 527 500 500 ASP ASP B . n B 1 528 GLY 528 501 501 GLY GLY B . n B 1 529 SER 529 502 502 SER SER B . n B 1 530 ILE 530 503 503 ILE ILE B . n B 1 531 VAL 531 504 504 VAL VAL B . n B 1 532 PHE 532 505 505 PHE PHE B . n B 1 533 LYS 533 506 506 LYS LYS B . n B 1 534 GLU 534 507 507 GLU GLU B . n B 1 535 VAL 535 508 508 VAL VAL B . n B 1 536 GLY 536 509 509 GLY GLY B . n B 1 537 TYR 537 510 510 TYR TYR B . n B 1 538 TYR 538 511 511 TYR TYR B . n B 1 539 ASN 539 512 512 ASN ASN B . n B 1 540 VAL 540 513 513 VAL VAL B . n B 1 541 TYR 541 514 514 TYR TYR B . n B 1 542 ALA 542 515 515 ALA ALA B . n B 1 543 LYS 543 516 516 LYS LYS B . n B 1 544 LYS 544 517 517 LYS LYS B . n B 1 545 GLY 545 518 518 GLY GLY B . n B 1 546 GLU 546 519 519 GLU GLU B . n B 1 547 ARG 547 520 520 ARG ARG B . n B 1 548 LEU 548 521 521 LEU LEU B . n B 1 549 PHE 549 522 522 PHE PHE B . n B 1 550 ILE 550 523 523 ILE ILE B . n B 1 551 ASN 551 524 524 ASN ASN B . n B 1 552 GLU 552 525 525 GLU GLU B . n B 1 553 GLU 553 526 526 GLU GLU B . n B 1 554 LYS 554 527 527 LYS LYS B . n B 1 555 ILE 555 528 528 ILE ILE B . n B 1 556 LEU 556 529 529 LEU LEU B . n B 1 557 TRP 557 530 530 TRP TRP B . n B 1 558 SER 558 531 531 SER SER B . n B 1 559 GLY 559 532 ? ? ? B . n B 1 560 PHE 560 533 ? ? ? B . n B 1 561 SER 561 534 ? ? ? B . n B 1 562 ARG 562 535 ? ? ? B . n B 1 563 GLU 563 536 ? ? ? B . n B 1 564 VAL 564 537 ? ? ? B . n B 1 565 PRO 565 538 ? ? ? B . n B 1 566 PHE 566 539 ? ? ? B . n B 1 567 SER 567 540 ? ? ? B . n B 1 568 ASN 568 541 ? ? ? B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 TCR 1 601 599 TCR ADW A . D 3 NAG 1 602 600 NAG NAG A . E 3 NAG 1 603 601 NAG NAG A . F 3 NAG 1 604 602 NAG NAG A . G 3 NAG 1 605 603 NAG NAG A . H 4 CL 1 606 700 CL CL A . I 4 CL 1 607 701 CL CL A . J 4 CL 1 608 702 CL CL A . K 5 BCT 1 609 750 BCT BCT A . L 6 MG 1 610 800 MG MG A . M 2 TCR 1 601 599 TCR ADW B . N 3 NAG 1 602 600 NAG NAG B . O 3 NAG 1 603 601 NAG NAG B . P 3 NAG 1 604 602 NAG NAG B . Q 3 NAG 1 605 603 NAG NAG B . R 4 CL 1 606 700 CL CL B . S 4 CL 1 607 701 CL CL B . T 4 CL 1 608 702 CL CL B . U 5 BCT 1 609 750 BCT BCT B . V 6 MG 1 610 800 MG MG B . W 6 MG 1 611 801 MG MG B . X 7 HOH 1 701 875 HOH HOH A . X 7 HOH 2 702 897 HOH HOH A . X 7 HOH 3 703 862 HOH HOH A . X 7 HOH 4 704 836 HOH HOH A . X 7 HOH 5 705 846 HOH HOH A . X 7 HOH 6 706 905 HOH HOH A . X 7 HOH 7 707 823 HOH HOH A . X 7 HOH 8 708 853 HOH HOH A . X 7 HOH 9 709 811 HOH HOH A . X 7 HOH 10 710 926 HOH HOH A . X 7 HOH 11 711 867 HOH HOH A . X 7 HOH 12 712 825 HOH HOH A . X 7 HOH 13 713 828 HOH HOH A . X 7 HOH 14 714 822 HOH HOH A . X 7 HOH 15 715 921 HOH HOH A . X 7 HOH 16 716 844 HOH HOH A . X 7 HOH 17 717 810 HOH HOH A . X 7 HOH 18 718 911 HOH HOH A . X 7 HOH 19 719 895 HOH HOH A . X 7 HOH 20 720 806 HOH HOH A . X 7 HOH 21 721 814 HOH HOH A . X 7 HOH 22 722 818 HOH HOH A . X 7 HOH 23 723 887 HOH HOH A . X 7 HOH 24 724 950 HOH HOH A . X 7 HOH 25 725 917 HOH HOH A . X 7 HOH 26 726 843 HOH HOH A . X 7 HOH 27 727 840 HOH HOH A . X 7 HOH 28 728 829 HOH HOH A . X 7 HOH 29 729 808 HOH HOH A . X 7 HOH 30 730 892 HOH HOH A . X 7 HOH 31 731 854 HOH HOH A . X 7 HOH 32 732 906 HOH HOH A . X 7 HOH 33 733 955 HOH HOH A . X 7 HOH 34 734 904 HOH HOH A . X 7 HOH 35 735 812 HOH HOH A . X 7 HOH 36 736 935 HOH HOH A . X 7 HOH 37 737 819 HOH HOH A . X 7 HOH 38 738 940 HOH HOH A . X 7 HOH 39 739 884 HOH HOH A . X 7 HOH 40 740 840 HOH HOH A . X 7 HOH 41 741 826 HOH HOH A . X 7 HOH 42 742 933 HOH HOH A . X 7 HOH 43 743 894 HOH HOH A . X 7 HOH 44 744 872 HOH HOH A . X 7 HOH 45 745 939 HOH HOH A . X 7 HOH 46 746 876 HOH HOH A . X 7 HOH 47 747 893 HOH HOH A . X 7 HOH 48 748 870 HOH HOH A . X 7 HOH 49 749 908 HOH HOH A . X 7 HOH 50 750 815 HOH HOH A . X 7 HOH 51 751 931 HOH HOH A . X 7 HOH 52 752 802 HOH HOH A . X 7 HOH 53 753 910 HOH HOH A . X 7 HOH 54 754 863 HOH HOH A . X 7 HOH 55 755 885 HOH HOH A . X 7 HOH 56 756 852 HOH HOH A . X 7 HOH 57 757 803 HOH HOH A . X 7 HOH 58 758 830 HOH HOH A . X 7 HOH 59 759 848 HOH HOH A . X 7 HOH 60 760 813 HOH HOH A . X 7 HOH 61 761 835 HOH HOH A . X 7 HOH 62 762 845 HOH HOH A . X 7 HOH 63 763 873 HOH HOH A . X 7 HOH 64 764 882 HOH HOH A . X 7 HOH 65 765 851 HOH HOH A . X 7 HOH 66 766 878 HOH HOH A . X 7 HOH 67 767 841 HOH HOH A . X 7 HOH 68 768 943 HOH HOH A . X 7 HOH 69 769 890 HOH HOH A . X 7 HOH 70 770 827 HOH HOH A . X 7 HOH 71 771 821 HOH HOH A . X 7 HOH 72 772 857 HOH HOH A . X 7 HOH 73 773 865 HOH HOH A . X 7 HOH 74 774 838 HOH HOH A . X 7 HOH 75 775 946 HOH HOH A . X 7 HOH 76 776 849 HOH HOH A . X 7 HOH 77 777 952 HOH HOH A . X 7 HOH 78 778 860 HOH HOH A . X 7 HOH 79 779 898 HOH HOH A . X 7 HOH 80 780 861 HOH HOH A . X 7 HOH 81 781 881 HOH HOH A . X 7 HOH 82 782 855 HOH HOH A . X 7 HOH 83 783 899 HOH HOH A . X 7 HOH 84 784 909 HOH HOH A . X 7 HOH 85 785 883 HOH HOH A . X 7 HOH 86 786 927 HOH HOH A . X 7 HOH 87 787 839 HOH HOH A . X 7 HOH 88 788 942 HOH HOH A . X 7 HOH 89 789 842 HOH HOH A . X 7 HOH 90 790 817 HOH HOH A . X 7 HOH 91 791 816 HOH HOH A . X 7 HOH 92 792 837 HOH HOH A . X 7 HOH 93 793 859 HOH HOH A . X 7 HOH 94 794 902 HOH HOH A . X 7 HOH 95 795 834 HOH HOH A . X 7 HOH 96 796 889 HOH HOH A . X 7 HOH 97 797 869 HOH HOH A . X 7 HOH 98 798 864 HOH HOH A . X 7 HOH 99 799 896 HOH HOH A . X 7 HOH 100 800 879 HOH HOH A . X 7 HOH 101 801 923 HOH HOH A . X 7 HOH 102 802 877 HOH HOH A . X 7 HOH 103 803 916 HOH HOH A . X 7 HOH 104 804 930 HOH HOH A . X 7 HOH 105 805 919 HOH HOH A . X 7 HOH 106 806 847 HOH HOH A . X 7 HOH 107 807 929 HOH HOH A . X 7 HOH 108 808 804 HOH HOH A . X 7 HOH 109 809 903 HOH HOH A . X 7 HOH 110 810 954 HOH HOH A . X 7 HOH 111 811 850 HOH HOH A . X 7 HOH 112 812 833 HOH HOH A . X 7 HOH 113 813 938 HOH HOH A . X 7 HOH 114 814 886 HOH HOH A . X 7 HOH 115 815 832 HOH HOH A . X 7 HOH 116 816 805 HOH HOH A . X 7 HOH 117 817 856 HOH HOH A . X 7 HOH 118 818 824 HOH HOH A . X 7 HOH 119 819 880 HOH HOH A . X 7 HOH 120 820 871 HOH HOH A . X 7 HOH 121 821 868 HOH HOH A . X 7 HOH 122 822 934 HOH HOH A . X 7 HOH 123 823 922 HOH HOH A . X 7 HOH 124 824 891 HOH HOH A . X 7 HOH 125 825 937 HOH HOH A . X 7 HOH 126 826 925 HOH HOH A . X 7 HOH 127 827 807 HOH HOH A . X 7 HOH 128 828 944 HOH HOH A . X 7 HOH 129 829 874 HOH HOH A . X 7 HOH 130 830 932 HOH HOH A . X 7 HOH 131 831 947 HOH HOH A . X 7 HOH 132 832 888 HOH HOH A . X 7 HOH 133 833 948 HOH HOH A . X 7 HOH 134 834 945 HOH HOH A . X 7 HOH 135 835 915 HOH HOH A . X 7 HOH 136 836 912 HOH HOH A . X 7 HOH 137 837 820 HOH HOH A . X 7 HOH 138 838 918 HOH HOH A . X 7 HOH 139 839 866 HOH HOH A . X 7 HOH 140 840 907 HOH HOH A . X 7 HOH 141 841 941 HOH HOH A . X 7 HOH 142 842 949 HOH HOH A . X 7 HOH 143 843 960 HOH HOH A . X 7 HOH 144 844 920 HOH HOH A . X 7 HOH 145 845 951 HOH HOH A . X 7 HOH 146 846 913 HOH HOH A . X 7 HOH 147 847 924 HOH HOH A . X 7 HOH 148 848 809 HOH HOH A . X 7 HOH 149 849 928 HOH HOH A . X 7 HOH 150 850 914 HOH HOH A . X 7 HOH 151 851 900 HOH HOH A . X 7 HOH 152 852 901 HOH HOH A . X 7 HOH 153 853 936 HOH HOH A . Y 7 HOH 1 701 915 HOH HOH B . Y 7 HOH 2 702 868 HOH HOH B . Y 7 HOH 3 703 899 HOH HOH B . Y 7 HOH 4 704 870 HOH HOH B . Y 7 HOH 5 705 859 HOH HOH B . Y 7 HOH 6 706 845 HOH HOH B . Y 7 HOH 7 707 907 HOH HOH B . Y 7 HOH 8 708 828 HOH HOH B . Y 7 HOH 9 709 833 HOH HOH B . Y 7 HOH 10 710 852 HOH HOH B . Y 7 HOH 11 711 932 HOH HOH B . Y 7 HOH 12 712 962 HOH HOH B . Y 7 HOH 13 713 972 HOH HOH B . Y 7 HOH 14 714 827 HOH HOH B . Y 7 HOH 15 715 829 HOH HOH B . Y 7 HOH 16 716 964 HOH HOH B . Y 7 HOH 17 717 854 HOH HOH B . Y 7 HOH 18 718 903 HOH HOH B . Y 7 HOH 19 719 902 HOH HOH B . Y 7 HOH 20 720 862 HOH HOH B . Y 7 HOH 21 721 892 HOH HOH B . Y 7 HOH 22 722 847 HOH HOH B . Y 7 HOH 23 723 956 HOH HOH B . Y 7 HOH 24 724 826 HOH HOH B . Y 7 HOH 25 725 825 HOH HOH B . Y 7 HOH 26 726 952 HOH HOH B . Y 7 HOH 27 727 906 HOH HOH B . Y 7 HOH 28 728 853 HOH HOH B . Y 7 HOH 29 729 817 HOH HOH B . Y 7 HOH 30 730 811 HOH HOH B . Y 7 HOH 31 731 881 HOH HOH B . Y 7 HOH 32 732 808 HOH HOH B . Y 7 HOH 33 733 823 HOH HOH B . Y 7 HOH 34 734 838 HOH HOH B . Y 7 HOH 35 735 872 HOH HOH B . Y 7 HOH 36 736 965 HOH HOH B . Y 7 HOH 37 737 949 HOH HOH B . Y 7 HOH 38 738 866 HOH HOH B . Y 7 HOH 39 739 911 HOH HOH B . Y 7 HOH 40 740 874 HOH HOH B . Y 7 HOH 41 741 875 HOH HOH B . Y 7 HOH 42 742 850 HOH HOH B . Y 7 HOH 43 743 947 HOH HOH B . Y 7 HOH 44 744 871 HOH HOH B . Y 7 HOH 45 745 869 HOH HOH B . Y 7 HOH 46 746 851 HOH HOH B . Y 7 HOH 47 747 832 HOH HOH B . Y 7 HOH 48 748 940 HOH HOH B . Y 7 HOH 49 749 967 HOH HOH B . Y 7 HOH 50 750 815 HOH HOH B . Y 7 HOH 51 751 835 HOH HOH B . Y 7 HOH 52 752 878 HOH HOH B . Y 7 HOH 53 753 970 HOH HOH B . Y 7 HOH 54 754 968 HOH HOH B . Y 7 HOH 55 755 858 HOH HOH B . Y 7 HOH 56 756 910 HOH HOH B . Y 7 HOH 57 757 806 HOH HOH B . Y 7 HOH 58 758 804 HOH HOH B . Y 7 HOH 59 759 841 HOH HOH B . Y 7 HOH 60 760 912 HOH HOH B . Y 7 HOH 61 761 921 HOH HOH B . Y 7 HOH 62 762 901 HOH HOH B . Y 7 HOH 63 763 818 HOH HOH B . Y 7 HOH 64 764 819 HOH HOH B . Y 7 HOH 65 765 904 HOH HOH B . Y 7 HOH 66 766 920 HOH HOH B . Y 7 HOH 67 767 863 HOH HOH B . Y 7 HOH 68 768 807 HOH HOH B . Y 7 HOH 69 769 861 HOH HOH B . Y 7 HOH 70 770 855 HOH HOH B . Y 7 HOH 71 771 931 HOH HOH B . Y 7 HOH 72 772 959 HOH HOH B . Y 7 HOH 73 773 898 HOH HOH B . Y 7 HOH 74 774 873 HOH HOH B . Y 7 HOH 75 775 876 HOH HOH B . Y 7 HOH 76 776 927 HOH HOH B . Y 7 HOH 77 777 839 HOH HOH B . Y 7 HOH 78 778 918 HOH HOH B . Y 7 HOH 79 779 831 HOH HOH B . Y 7 HOH 80 780 879 HOH HOH B . Y 7 HOH 81 781 917 HOH HOH B . Y 7 HOH 82 782 865 HOH HOH B . Y 7 HOH 83 783 900 HOH HOH B . Y 7 HOH 84 784 916 HOH HOH B . Y 7 HOH 85 785 934 HOH HOH B . Y 7 HOH 86 786 914 HOH HOH B . Y 7 HOH 87 787 848 HOH HOH B . Y 7 HOH 88 788 953 HOH HOH B . Y 7 HOH 89 789 963 HOH HOH B . Y 7 HOH 90 790 812 HOH HOH B . Y 7 HOH 91 791 842 HOH HOH B . Y 7 HOH 92 792 843 HOH HOH B . Y 7 HOH 93 793 939 HOH HOH B . Y 7 HOH 94 794 821 HOH HOH B . Y 7 HOH 95 795 894 HOH HOH B . Y 7 HOH 96 796 857 HOH HOH B . Y 7 HOH 97 797 814 HOH HOH B . Y 7 HOH 98 798 813 HOH HOH B . Y 7 HOH 99 799 834 HOH HOH B . Y 7 HOH 100 800 897 HOH HOH B . Y 7 HOH 101 801 905 HOH HOH B . Y 7 HOH 102 802 877 HOH HOH B . Y 7 HOH 103 803 864 HOH HOH B . Y 7 HOH 104 804 893 HOH HOH B . Y 7 HOH 105 805 896 HOH HOH B . Y 7 HOH 106 806 937 HOH HOH B . Y 7 HOH 107 807 971 HOH HOH B . Y 7 HOH 108 808 803 HOH HOH B . Y 7 HOH 109 809 824 HOH HOH B . Y 7 HOH 110 810 913 HOH HOH B . Y 7 HOH 111 811 933 HOH HOH B . Y 7 HOH 112 812 909 HOH HOH B . Y 7 HOH 113 813 846 HOH HOH B . Y 7 HOH 114 814 884 HOH HOH B . Y 7 HOH 115 815 867 HOH HOH B . Y 7 HOH 116 816 830 HOH HOH B . Y 7 HOH 117 817 890 HOH HOH B . Y 7 HOH 118 818 941 HOH HOH B . Y 7 HOH 119 819 860 HOH HOH B . Y 7 HOH 120 820 919 HOH HOH B . Y 7 HOH 121 821 809 HOH HOH B . Y 7 HOH 122 822 957 HOH HOH B . Y 7 HOH 123 823 948 HOH HOH B . Y 7 HOH 124 824 883 HOH HOH B . Y 7 HOH 125 825 925 HOH HOH B . Y 7 HOH 126 826 954 HOH HOH B . Y 7 HOH 127 827 882 HOH HOH B . Y 7 HOH 128 828 961 HOH HOH B . Y 7 HOH 129 829 955 HOH HOH B . Y 7 HOH 130 830 805 HOH HOH B . Y 7 HOH 131 831 844 HOH HOH B . Y 7 HOH 132 832 856 HOH HOH B . Y 7 HOH 133 833 924 HOH HOH B . Y 7 HOH 134 834 887 HOH HOH B . Y 7 HOH 135 835 891 HOH HOH B . Y 7 HOH 136 836 820 HOH HOH B . Y 7 HOH 137 837 944 HOH HOH B . Y 7 HOH 138 838 885 HOH HOH B . Y 7 HOH 139 839 951 HOH HOH B . Y 7 HOH 140 840 950 HOH HOH B . Y 7 HOH 141 841 889 HOH HOH B . Y 7 HOH 142 842 922 HOH HOH B . Y 7 HOH 143 843 943 HOH HOH B . Y 7 HOH 144 844 908 HOH HOH B . Y 7 HOH 145 845 837 HOH HOH B . Y 7 HOH 146 846 810 HOH HOH B . Y 7 HOH 147 847 945 HOH HOH B . Y 7 HOH 148 848 935 HOH HOH B . Y 7 HOH 149 849 936 HOH HOH B . Y 7 HOH 150 850 888 HOH HOH B . Y 7 HOH 151 851 969 HOH HOH B . Y 7 HOH 152 852 928 HOH HOH B . Y 7 HOH 153 853 966 HOH HOH B . Y 7 HOH 154 854 858 HOH HOH B . Y 7 HOH 155 855 836 HOH HOH B . Y 7 HOH 156 856 923 HOH HOH B . Y 7 HOH 157 857 938 HOH HOH B . Y 7 HOH 158 858 946 HOH HOH B . Y 7 HOH 159 859 926 HOH HOH B . Y 7 HOH 160 860 822 HOH HOH B . Y 7 HOH 161 861 849 HOH HOH B . Y 7 HOH 162 862 942 HOH HOH B . Y 7 HOH 163 863 880 HOH HOH B . Y 7 HOH 164 864 930 HOH HOH B . Y 7 HOH 165 865 816 HOH HOH B . Y 7 HOH 166 866 886 HOH HOH B . Y 7 HOH 167 867 895 HOH HOH B . Y 7 HOH 168 868 831 HOH HOH B . Y 7 HOH 169 869 929 HOH HOH B . Y 7 HOH 170 870 958 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A CSO 263 A CSO 236 ? CYS 'modified residue' 2 A CSO 509 A CSO 482 ? CYS 'modified residue' 3 B CSO 263 B CSO 236 ? CYS 'modified residue' 4 B CSO 509 B CSO 482 ? CYS 'modified residue' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 8310 ? 1 MORE -87 ? 1 'SSA (A^2)' 38740 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 O ? A ILE 108 ? A ILE 81 ? 1_555 MG ? L MG . ? A MG 610 ? 1_555 O ? A SER 111 ? A SER 84 ? 1_555 74.9 ? 2 O ? A ILE 108 ? A ILE 81 ? 1_555 MG ? L MG . ? A MG 610 ? 1_555 O ? A LEU 114 ? A LEU 87 ? 1_555 102.8 ? 3 O ? A SER 111 ? A SER 84 ? 1_555 MG ? L MG . ? A MG 610 ? 1_555 O ? A LEU 114 ? A LEU 87 ? 1_555 79.0 ? 4 O ? A ILE 108 ? A ILE 81 ? 1_555 MG ? L MG . ? A MG 610 ? 1_555 O ? X HOH . ? A HOH 732 ? 1_555 94.5 ? 5 O ? A SER 111 ? A SER 84 ? 1_555 MG ? L MG . ? A MG 610 ? 1_555 O ? X HOH . ? A HOH 732 ? 1_555 161.7 ? 6 O ? A LEU 114 ? A LEU 87 ? 1_555 MG ? L MG . ? A MG 610 ? 1_555 O ? X HOH . ? A HOH 732 ? 1_555 118.4 ? 7 O ? B ILE 108 ? B ILE 81 ? 1_555 MG ? W MG . ? B MG 611 ? 1_555 O ? B SER 111 ? B SER 84 ? 1_555 79.4 ? 8 O ? B ILE 108 ? B ILE 81 ? 1_555 MG ? W MG . ? B MG 611 ? 1_555 O ? B LEU 114 ? B LEU 87 ? 1_555 103.9 ? 9 O ? B SER 111 ? B SER 84 ? 1_555 MG ? W MG . ? B MG 611 ? 1_555 O ? B LEU 114 ? B LEU 87 ? 1_555 78.6 ? 10 O ? B ILE 108 ? B ILE 81 ? 1_555 MG ? W MG . ? B MG 611 ? 1_555 O ? Y HOH . ? B HOH 773 ? 1_555 101.7 ? 11 O ? B SER 111 ? B SER 84 ? 1_555 MG ? W MG . ? B MG 611 ? 1_555 O ? Y HOH . ? B HOH 773 ? 1_555 172.9 ? 12 O ? B LEU 114 ? B LEU 87 ? 1_555 MG ? W MG . ? B MG 611 ? 1_555 O ? Y HOH . ? B HOH 773 ? 1_555 107.8 ? 13 O ? B ILE 108 ? B ILE 81 ? 1_555 MG ? W MG . ? B MG 611 ? 1_555 O ? Y HOH . ? B HOH 820 ? 1_555 132.9 ? 14 O ? B SER 111 ? B SER 84 ? 1_555 MG ? W MG . ? B MG 611 ? 1_555 O ? Y HOH . ? B HOH 820 ? 1_555 83.3 ? 15 O ? B LEU 114 ? B LEU 87 ? 1_555 MG ? W MG . ? B MG 611 ? 1_555 O ? Y HOH . ? B HOH 820 ? 1_555 115.0 ? 16 O ? Y HOH . ? B HOH 773 ? 1_555 MG ? W MG . ? B MG 611 ? 1_555 O ? Y HOH . ? B HOH 820 ? 1_555 91.0 ? 17 O ? B SER 267 ? B SER 240 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 OG ? B SER 267 ? B SER 240 ? 1_555 82.5 ? 18 O ? B SER 267 ? B SER 240 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? Y HOH . ? B HOH 817 ? 1_555 87.4 ? 19 OG ? B SER 267 ? B SER 240 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? Y HOH . ? B HOH 817 ? 1_555 169.3 ? 20 O ? B SER 267 ? B SER 240 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? Y HOH . ? B HOH 838 ? 1_555 89.4 ? 21 OG ? B SER 267 ? B SER 240 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? Y HOH . ? B HOH 838 ? 1_555 92.9 ? 22 O ? Y HOH . ? B HOH 817 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? Y HOH . ? B HOH 838 ? 1_555 90.3 ? 23 O ? B SER 267 ? B SER 240 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? X HOH . ? A HOH 740 ? 1_555 171.3 ? 24 OG ? B SER 267 ? B SER 240 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? X HOH . ? A HOH 740 ? 1_555 89.4 ? 25 O ? Y HOH . ? B HOH 817 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? X HOH . ? A HOH 740 ? 1_555 100.9 ? 26 O ? Y HOH . ? B HOH 838 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? X HOH . ? A HOH 740 ? 1_555 87.9 ? 27 O ? B SER 267 ? B SER 240 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? Y HOH . ? B HOH 800 ? 1_555 85.9 ? 28 OG ? B SER 267 ? B SER 240 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? Y HOH . ? B HOH 800 ? 1_555 86.6 ? 29 O ? Y HOH . ? B HOH 817 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? Y HOH . ? B HOH 800 ? 1_555 89.4 ? 30 O ? Y HOH . ? B HOH 838 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? Y HOH . ? B HOH 800 ? 1_555 175.3 ? 31 O ? X HOH . ? A HOH 740 ? 1_555 MG ? V MG . ? B MG 610 ? 1_555 O ? Y HOH . ? B HOH 800 ? 1_555 96.8 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2016-06-22 2 'Structure model' 1 1 2016-07-20 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Database references' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0049 1 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? SCALEPACK ? ? ? . 2 ? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? 3.15 3 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 4 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? . 5 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CA A LEU 37 ? ? CB A LEU 37 ? ? CG A LEU 37 ? ? 129.44 115.30 14.14 2.30 N 2 1 CB B VAL 337 ? ? CA B VAL 337 ? ? C B VAL 337 ? ? 99.00 111.40 -12.40 1.90 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 23 ? ? -68.99 -70.27 2 1 ARG A 62 ? ? 72.37 97.18 3 1 ALA A 168 ? ? -145.24 -9.24 4 1 PHE A 180 ? ? -118.87 79.02 5 1 ARG A 415 ? ? -122.63 -75.55 6 1 SER A 531 ? ? 54.87 15.54 7 1 ARG B 62 ? ? 72.59 96.47 8 1 THR B 145 ? ? -90.27 -69.27 9 1 ALA B 168 ? ? -146.28 -11.94 10 1 PHE B 180 ? ? -117.28 78.88 11 1 ASN B 207 ? ? -142.23 11.00 12 1 ARG B 415 ? ? -120.98 -75.79 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A PRO 22 ? CG ? A PRO 49 CG 2 1 Y 1 A PRO 22 ? CD ? A PRO 49 CD 3 1 Y 1 A ASP 23 ? CG ? A ASP 50 CG 4 1 Y 1 A ASP 23 ? OD1 ? A ASP 50 OD1 5 1 Y 1 A ASP 23 ? OD2 ? A ASP 50 OD2 6 1 Y 1 A LYS 29 ? CG ? A LYS 56 CG 7 1 Y 1 A LYS 29 ? CD ? A LYS 56 CD 8 1 Y 1 A LYS 29 ? CE ? A LYS 56 CE 9 1 Y 1 A LYS 29 ? NZ ? A LYS 56 NZ 10 1 Y 1 A LYS 47 ? CG ? A LYS 74 CG 11 1 Y 1 A LYS 47 ? CD ? A LYS 74 CD 12 1 Y 1 A LYS 47 ? CE ? A LYS 74 CE 13 1 Y 1 A LYS 47 ? NZ ? A LYS 74 NZ 14 1 Y 1 A ASP 48 ? CG ? A ASP 75 CG 15 1 Y 1 A ASP 48 ? OD1 ? A ASP 75 OD1 16 1 Y 1 A ASP 48 ? OD2 ? A ASP 75 OD2 17 1 Y 1 A GLU 56 ? CG ? A GLU 83 CG 18 1 Y 1 A GLU 56 ? CD ? A GLU 83 CD 19 1 Y 1 A GLU 56 ? OE1 ? A GLU 83 OE1 20 1 Y 1 A GLU 56 ? OE2 ? A GLU 83 OE2 21 1 Y 1 A ASN 90 ? CG ? A ASN 117 CG 22 1 Y 1 A ASN 90 ? OD1 ? A ASN 117 OD1 23 1 Y 1 A ASN 90 ? ND2 ? A ASN 117 ND2 24 1 Y 1 A LEU 91 ? CG ? A LEU 118 CG 25 1 Y 1 A LEU 91 ? CD1 ? A LEU 118 CD1 26 1 Y 1 A LEU 91 ? CD2 ? A LEU 118 CD2 27 1 Y 1 A SER 122 ? OG ? A SER 149 OG 28 1 Y 1 A ASN 124 ? CG ? A ASN 151 CG 29 1 Y 1 A ASN 124 ? OD1 ? A ASN 151 OD1 30 1 Y 1 A ASN 124 ? ND2 ? A ASN 151 ND2 31 1 Y 1 A ASP 126 ? CG ? A ASP 153 CG 32 1 Y 1 A ASP 126 ? OD1 ? A ASP 153 OD1 33 1 Y 1 A ASP 126 ? OD2 ? A ASP 153 OD2 34 1 Y 1 A PHE 128 ? CG ? A PHE 155 CG 35 1 Y 1 A PHE 128 ? CD1 ? A PHE 155 CD1 36 1 Y 1 A PHE 128 ? CD2 ? A PHE 155 CD2 37 1 Y 1 A PHE 128 ? CE1 ? A PHE 155 CE1 38 1 Y 1 A PHE 128 ? CE2 ? A PHE 155 CE2 39 1 Y 1 A PHE 128 ? CZ ? A PHE 155 CZ 40 1 Y 1 A CYS 129 ? SG ? A CYS 156 SG 41 1 Y 1 A ASN 130 ? CG ? A ASN 157 CG 42 1 Y 1 A ASN 130 ? OD1 ? A ASN 157 OD1 43 1 Y 1 A ASN 130 ? ND2 ? A ASN 157 ND2 44 1 Y 1 A GLU 133 ? CG ? A GLU 160 CG 45 1 Y 1 A GLU 133 ? CD ? A GLU 160 CD 46 1 Y 1 A GLU 133 ? OE1 ? A GLU 160 OE1 47 1 Y 1 A GLU 133 ? OE2 ? A GLU 160 OE2 48 1 Y 1 A LYS 336 ? CG ? A LYS 363 CG 49 1 Y 1 A LYS 336 ? CD ? A LYS 363 CD 50 1 Y 1 A LYS 336 ? CE ? A LYS 363 CE 51 1 Y 1 A LYS 336 ? NZ ? A LYS 363 NZ 52 1 Y 1 A ARG 340 ? CG ? A ARG 367 CG 53 1 Y 1 A ARG 340 ? CD ? A ARG 367 CD 54 1 Y 1 A ARG 340 ? NE ? A ARG 367 NE 55 1 Y 1 A ARG 340 ? CZ ? A ARG 367 CZ 56 1 Y 1 A ARG 340 ? NH1 ? A ARG 367 NH1 57 1 Y 1 A ARG 340 ? NH2 ? A ARG 367 NH2 58 1 Y 1 A LYS 341 ? CG ? A LYS 368 CG 59 1 Y 1 A LYS 341 ? CD ? A LYS 368 CD 60 1 Y 1 A LYS 341 ? CE ? A LYS 368 CE 61 1 Y 1 A LYS 341 ? NZ ? A LYS 368 NZ 62 1 Y 1 A VAL 343 ? CG1 ? A VAL 370 CG1 63 1 Y 1 A VAL 343 ? CG2 ? A VAL 370 CG2 64 1 Y 1 A LYS 349 ? CG ? A LYS 376 CG 65 1 Y 1 A LYS 349 ? CD ? A LYS 376 CD 66 1 Y 1 A LYS 349 ? CE ? A LYS 376 CE 67 1 Y 1 A LYS 349 ? NZ ? A LYS 376 NZ 68 1 Y 1 A ASN 357 ? CG ? A ASN 384 CG 69 1 Y 1 A ASN 357 ? OD1 ? A ASN 384 OD1 70 1 Y 1 A ASN 357 ? ND2 ? A ASN 384 ND2 71 1 Y 1 A HIS 359 ? CG ? A HIS 386 CG 72 1 Y 1 A HIS 359 ? ND1 ? A HIS 386 ND1 73 1 Y 1 A HIS 359 ? CD2 ? A HIS 386 CD2 74 1 Y 1 A HIS 359 ? CE1 ? A HIS 386 CE1 75 1 Y 1 A HIS 359 ? NE2 ? A HIS 386 NE2 76 1 Y 1 A ARG 392 ? CG ? A ARG 419 CG 77 1 Y 1 A ARG 392 ? CD ? A ARG 419 CD 78 1 Y 1 A ARG 392 ? NE ? A ARG 419 NE 79 1 Y 1 A ARG 392 ? CZ ? A ARG 419 CZ 80 1 Y 1 A ARG 392 ? NH1 ? A ARG 419 NH1 81 1 Y 1 A ARG 392 ? NH2 ? A ARG 419 NH2 82 1 Y 1 A ARG 441 ? CG ? A ARG 468 CG 83 1 Y 1 A ARG 441 ? CD ? A ARG 468 CD 84 1 Y 1 A ARG 441 ? NE ? A ARG 468 NE 85 1 Y 1 A ARG 441 ? CZ ? A ARG 468 CZ 86 1 Y 1 A ARG 441 ? NH1 ? A ARG 468 NH1 87 1 Y 1 A ARG 441 ? NH2 ? A ARG 468 NH2 88 1 Y 1 A SER 448 ? OG ? A SER 475 OG 89 1 Y 1 A LYS 453 ? CG ? A LYS 480 CG 90 1 Y 1 A LYS 453 ? CD ? A LYS 480 CD 91 1 Y 1 A LYS 453 ? CE ? A LYS 480 CE 92 1 Y 1 A LYS 453 ? NZ ? A LYS 480 NZ 93 1 Y 1 A LYS 454 ? CG ? A LYS 481 CG 94 1 Y 1 A LYS 454 ? CD ? A LYS 481 CD 95 1 Y 1 A LYS 454 ? CE ? A LYS 481 CE 96 1 Y 1 A LYS 454 ? NZ ? A LYS 481 NZ 97 1 Y 1 A LYS 516 ? CG ? A LYS 543 CG 98 1 Y 1 A LYS 516 ? CD ? A LYS 543 CD 99 1 Y 1 A LYS 516 ? CE ? A LYS 543 CE 100 1 Y 1 A LYS 516 ? NZ ? A LYS 543 NZ 101 1 Y 1 A GLU 526 ? CG ? A GLU 553 CG 102 1 Y 1 A GLU 526 ? CD ? A GLU 553 CD 103 1 Y 1 A GLU 526 ? OE1 ? A GLU 553 OE1 104 1 Y 1 A GLU 526 ? OE2 ? A GLU 553 OE2 105 1 Y 1 B LYS 29 ? CG ? B LYS 56 CG 106 1 Y 1 B LYS 29 ? CD ? B LYS 56 CD 107 1 Y 1 B LYS 29 ? CE ? B LYS 56 CE 108 1 Y 1 B LYS 29 ? NZ ? B LYS 56 NZ 109 1 Y 1 B GLU 59 ? CG ? B GLU 86 CG 110 1 Y 1 B GLU 59 ? CD ? B GLU 86 CD 111 1 Y 1 B GLU 59 ? OE1 ? B GLU 86 OE1 112 1 Y 1 B GLU 59 ? OE2 ? B GLU 86 OE2 113 1 Y 1 B ASN 90 ? CG ? B ASN 117 CG 114 1 Y 1 B ASN 90 ? OD1 ? B ASN 117 OD1 115 1 Y 1 B ASN 90 ? ND2 ? B ASN 117 ND2 116 1 Y 1 B ILE 120 ? CG1 ? B ILE 147 CG1 117 1 Y 1 B ILE 120 ? CG2 ? B ILE 147 CG2 118 1 Y 1 B ILE 120 ? CD1 ? B ILE 147 CD1 119 1 Y 1 B GLU 249 ? CG ? B GLU 276 CG 120 1 Y 1 B GLU 249 ? CD ? B GLU 276 CD 121 1 Y 1 B GLU 249 ? OE1 ? B GLU 276 OE1 122 1 Y 1 B GLU 249 ? OE2 ? B GLU 276 OE2 123 1 Y 1 B GLU 250 ? CG ? B GLU 277 CG 124 1 Y 1 B GLU 250 ? CD ? B GLU 277 CD 125 1 Y 1 B GLU 250 ? OE1 ? B GLU 277 OE1 126 1 Y 1 B GLU 250 ? OE2 ? B GLU 277 OE2 127 1 Y 1 B GLU 332 ? CG ? B GLU 359 CG 128 1 Y 1 B GLU 332 ? CD ? B GLU 359 CD 129 1 Y 1 B GLU 332 ? OE1 ? B GLU 359 OE1 130 1 Y 1 B GLU 332 ? OE2 ? B GLU 359 OE2 131 1 Y 1 B ARG 340 ? CG ? B ARG 367 CG 132 1 Y 1 B ARG 340 ? CD ? B ARG 367 CD 133 1 Y 1 B ARG 340 ? NE ? B ARG 367 NE 134 1 Y 1 B ARG 340 ? CZ ? B ARG 367 CZ 135 1 Y 1 B ARG 340 ? NH1 ? B ARG 367 NH1 136 1 Y 1 B ARG 340 ? NH2 ? B ARG 367 NH2 137 1 Y 1 B LYS 341 ? CG ? B LYS 368 CG 138 1 Y 1 B LYS 341 ? CD ? B LYS 368 CD 139 1 Y 1 B LYS 341 ? CE ? B LYS 368 CE 140 1 Y 1 B LYS 341 ? NZ ? B LYS 368 NZ 141 1 Y 1 B VAL 343 ? CG1 ? B VAL 370 CG1 142 1 Y 1 B VAL 343 ? CG2 ? B VAL 370 CG2 143 1 Y 1 B LYS 349 ? CG ? B LYS 376 CG 144 1 Y 1 B LYS 349 ? CD ? B LYS 376 CD 145 1 Y 1 B LYS 349 ? CE ? B LYS 376 CE 146 1 Y 1 B LYS 349 ? NZ ? B LYS 376 NZ 147 1 Y 1 B GLN 361 ? CG ? B GLN 388 CG 148 1 Y 1 B GLN 361 ? CD ? B GLN 388 CD 149 1 Y 1 B GLN 361 ? OE1 ? B GLN 388 OE1 150 1 Y 1 B GLN 361 ? NE2 ? B GLN 388 NE2 151 1 Y 1 B LEU 394 ? CG ? B LEU 421 CG 152 1 Y 1 B LEU 394 ? CD1 ? B LEU 421 CD1 153 1 Y 1 B LEU 394 ? CD2 ? B LEU 421 CD2 154 1 Y 1 B SER 402 ? OG ? B SER 429 OG 155 1 Y 1 B GLU 405 ? CG ? B GLU 432 CG 156 1 Y 1 B GLU 405 ? CD ? B GLU 432 CD 157 1 Y 1 B GLU 405 ? OE1 ? B GLU 432 OE1 158 1 Y 1 B GLU 405 ? OE2 ? B GLU 432 OE2 159 1 Y 1 B ARG 441 ? CG ? B ARG 468 CG 160 1 Y 1 B ARG 441 ? CD ? B ARG 468 CD 161 1 Y 1 B ARG 441 ? NE ? B ARG 468 NE 162 1 Y 1 B ARG 441 ? CZ ? B ARG 468 CZ 163 1 Y 1 B ARG 441 ? NH1 ? B ARG 468 NH1 164 1 Y 1 B ARG 441 ? NH2 ? B ARG 468 NH2 165 1 Y 1 B LYS 454 ? CG ? B LYS 481 CG 166 1 Y 1 B LYS 454 ? CD ? B LYS 481 CD 167 1 Y 1 B LYS 454 ? CE ? B LYS 481 CE 168 1 Y 1 B LYS 454 ? NZ ? B LYS 481 NZ 169 1 Y 1 B GLU 481 ? CG ? B GLU 508 CG 170 1 Y 1 B GLU 481 ? CD ? B GLU 508 CD 171 1 Y 1 B GLU 481 ? OE1 ? B GLU 508 OE1 172 1 Y 1 B GLU 481 ? OE2 ? B GLU 508 OE2 173 1 Y 1 B GLU 499 ? CG ? B GLU 526 CG 174 1 Y 1 B GLU 499 ? CD ? B GLU 526 CD 175 1 Y 1 B GLU 499 ? OE1 ? B GLU 526 OE1 176 1 Y 1 B GLU 499 ? OE2 ? B GLU 526 OE2 177 1 Y 1 B LYS 516 ? CG ? B LYS 543 CG 178 1 Y 1 B LYS 516 ? CD ? B LYS 543 CD 179 1 Y 1 B LYS 516 ? CE ? B LYS 543 CE 180 1 Y 1 B LYS 516 ? NZ ? B LYS 543 NZ 181 1 Y 1 B GLU 519 ? CG ? B GLU 546 CG 182 1 Y 1 B GLU 519 ? CD ? B GLU 546 CD 183 1 Y 1 B GLU 519 ? OE1 ? B GLU 546 OE1 184 1 Y 1 B GLU 519 ? OE2 ? B GLU 546 OE2 185 1 Y 1 B LEU 529 ? CG ? B LEU 556 CG 186 1 Y 1 B LEU 529 ? CD1 ? B LEU 556 CD1 187 1 Y 1 B LEU 529 ? CD2 ? B LEU 556 CD2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A MET -26 ? A MET 1 2 1 Y 1 A ARG -25 ? A ARG 2 3 1 Y 1 A LEU -24 ? A LEU 3 4 1 Y 1 A LEU -23 ? A LEU 4 5 1 Y 1 A THR -22 ? A THR 5 6 1 Y 1 A ALA -21 ? A ALA 6 7 1 Y 1 A LEU -20 ? A LEU 7 8 1 Y 1 A PHE -19 ? A PHE 8 9 1 Y 1 A ALA -18 ? A ALA 9 10 1 Y 1 A TYR -17 ? A TYR 10 11 1 Y 1 A PHE -16 ? A PHE 11 12 1 Y 1 A ILE -15 ? A ILE 12 13 1 Y 1 A VAL -14 ? A VAL 13 14 1 Y 1 A ALA -13 ? A ALA 14 15 1 Y 1 A LEU -12 ? A LEU 15 16 1 Y 1 A ILE -11 ? A ILE 16 17 1 Y 1 A LEU -10 ? A LEU 17 18 1 Y 1 A ALA -9 ? A ALA 18 19 1 Y 1 A PHE -8 ? A PHE 19 20 1 Y 1 A SER -7 ? A SER 20 21 1 Y 1 A VAL -6 ? A VAL 21 22 1 Y 1 A SER -5 ? A SER 22 23 1 Y 1 A ALA -4 ? A ALA 23 24 1 Y 1 A LYS -3 ? A LYS 24 25 1 Y 1 A SER -2 ? A SER 25 26 1 Y 1 A MET -1 ? A MET 26 27 1 Y 1 A HIS 0 ? A HIS 27 28 1 Y 1 A HIS 1 ? A HIS 28 29 1 Y 1 A HIS 2 ? A HIS 29 30 1 Y 1 A HIS 3 ? A HIS 30 31 1 Y 1 A HIS 4 ? A HIS 31 32 1 Y 1 A HIS 5 ? A HIS 32 33 1 Y 1 A HIS 6 ? A HIS 33 34 1 Y 1 A HIS 7 ? A HIS 34 35 1 Y 1 A SER 8 ? A SER 35 36 1 Y 1 A ALA 9 ? A ALA 36 37 1 Y 1 A TRP 10 ? A TRP 37 38 1 Y 1 A SER 11 ? A SER 38 39 1 Y 1 A HIS 12 ? A HIS 39 40 1 Y 1 A PRO 13 ? A PRO 40 41 1 Y 1 A GLN 14 ? A GLN 41 42 1 Y 1 A PHE 15 ? A PHE 42 43 1 Y 1 A GLU 16 ? A GLU 43 44 1 Y 1 A LYS 17 ? A LYS 44 45 1 Y 1 A GLU 18 ? A GLU 45 46 1 Y 1 A PHE 19 ? A PHE 46 47 1 Y 1 A TYR 20 ? A TYR 47 48 1 Y 1 A GLY 21 ? A GLY 48 49 1 Y 1 A GLN 361 ? A GLN 388 50 1 Y 1 A GLU 362 ? A GLU 389 51 1 Y 1 A GLY 363 ? A GLY 390 52 1 Y 1 A ALA 364 ? A ALA 391 53 1 Y 1 A LYS 365 ? A LYS 392 54 1 Y 1 A GLY 366 ? A GLY 393 55 1 Y 1 A PRO 367 ? A PRO 394 56 1 Y 1 A LEU 368 ? A LEU 395 57 1 Y 1 A PRO 369 ? A PRO 396 58 1 Y 1 A VAL 370 ? A VAL 397 59 1 Y 1 A ASP 371 ? A ASP 398 60 1 Y 1 A THR 372 ? A THR 399 61 1 Y 1 A PHE 373 ? A PHE 400 62 1 Y 1 A LEU 374 ? A LEU 401 63 1 Y 1 A ARG 375 ? A ARG 402 64 1 Y 1 A GLY 376 ? A GLY 403 65 1 Y 1 A HIS 377 ? A HIS 404 66 1 Y 1 A GLU 378 ? A GLU 405 67 1 Y 1 A GLU 379 ? A GLU 406 68 1 Y 1 A SER 380 ? A SER 407 69 1 Y 1 A GLY 381 ? A GLY 408 70 1 Y 1 A ASP 382 ? A ASP 409 71 1 Y 1 A ARG 383 ? A ARG 410 72 1 Y 1 A PHE 384 ? A PHE 411 73 1 Y 1 A SER 385 ? A SER 412 74 1 Y 1 A ASN 386 ? A ASN 413 75 1 Y 1 A SER 387 ? A SER 414 76 1 Y 1 A SER 388 ? A SER 415 77 1 Y 1 A THR 389 ? A THR 416 78 1 Y 1 A ALA 390 ? A ALA 417 79 1 Y 1 A PHE 391 ? A PHE 418 80 1 Y 1 A SER 540 ? A SER 567 81 1 Y 1 A ASN 541 ? A ASN 568 82 1 Y 1 B MET -26 ? B MET 1 83 1 Y 1 B ARG -25 ? B ARG 2 84 1 Y 1 B LEU -24 ? B LEU 3 85 1 Y 1 B LEU -23 ? B LEU 4 86 1 Y 1 B THR -22 ? B THR 5 87 1 Y 1 B ALA -21 ? B ALA 6 88 1 Y 1 B LEU -20 ? B LEU 7 89 1 Y 1 B PHE -19 ? B PHE 8 90 1 Y 1 B ALA -18 ? B ALA 9 91 1 Y 1 B TYR -17 ? B TYR 10 92 1 Y 1 B PHE -16 ? B PHE 11 93 1 Y 1 B ILE -15 ? B ILE 12 94 1 Y 1 B VAL -14 ? B VAL 13 95 1 Y 1 B ALA -13 ? B ALA 14 96 1 Y 1 B LEU -12 ? B LEU 15 97 1 Y 1 B ILE -11 ? B ILE 16 98 1 Y 1 B LEU -10 ? B LEU 17 99 1 Y 1 B ALA -9 ? B ALA 18 100 1 Y 1 B PHE -8 ? B PHE 19 101 1 Y 1 B SER -7 ? B SER 20 102 1 Y 1 B VAL -6 ? B VAL 21 103 1 Y 1 B SER -5 ? B SER 22 104 1 Y 1 B ALA -4 ? B ALA 23 105 1 Y 1 B LYS -3 ? B LYS 24 106 1 Y 1 B SER -2 ? B SER 25 107 1 Y 1 B MET -1 ? B MET 26 108 1 Y 1 B HIS 0 ? B HIS 27 109 1 Y 1 B HIS 1 ? B HIS 28 110 1 Y 1 B HIS 2 ? B HIS 29 111 1 Y 1 B HIS 3 ? B HIS 30 112 1 Y 1 B HIS 4 ? B HIS 31 113 1 Y 1 B HIS 5 ? B HIS 32 114 1 Y 1 B HIS 6 ? B HIS 33 115 1 Y 1 B HIS 7 ? B HIS 34 116 1 Y 1 B SER 8 ? B SER 35 117 1 Y 1 B ALA 9 ? B ALA 36 118 1 Y 1 B TRP 10 ? B TRP 37 119 1 Y 1 B SER 11 ? B SER 38 120 1 Y 1 B HIS 12 ? B HIS 39 121 1 Y 1 B PRO 13 ? B PRO 40 122 1 Y 1 B GLN 14 ? B GLN 41 123 1 Y 1 B PHE 15 ? B PHE 42 124 1 Y 1 B GLU 16 ? B GLU 43 125 1 Y 1 B LYS 17 ? B LYS 44 126 1 Y 1 B GLU 18 ? B GLU 45 127 1 Y 1 B PHE 19 ? B PHE 46 128 1 Y 1 B TYR 20 ? B TYR 47 129 1 Y 1 B SER 122 ? B SER 149 130 1 Y 1 B LEU 123 ? B LEU 150 131 1 Y 1 B ASN 124 ? B ASN 151 132 1 Y 1 B LEU 125 ? B LEU 152 133 1 Y 1 B ASP 126 ? B ASP 153 134 1 Y 1 B GLU 127 ? B GLU 154 135 1 Y 1 B PHE 128 ? B PHE 155 136 1 Y 1 B CYS 129 ? B CYS 156 137 1 Y 1 B ASN 130 ? B ASN 157 138 1 Y 1 B CYS 131 ? B CYS 158 139 1 Y 1 B SER 132 ? B SER 159 140 1 Y 1 B GLU 133 ? B GLU 160 141 1 Y 1 B HIS 134 ? B HIS 161 142 1 Y 1 B ILE 135 ? B ILE 162 143 1 Y 1 B PRO 136 ? B PRO 163 144 1 Y 1 B GLU 362 ? B GLU 389 145 1 Y 1 B GLY 363 ? B GLY 390 146 1 Y 1 B ALA 364 ? B ALA 391 147 1 Y 1 B LYS 365 ? B LYS 392 148 1 Y 1 B GLY 366 ? B GLY 393 149 1 Y 1 B PRO 367 ? B PRO 394 150 1 Y 1 B LEU 368 ? B LEU 395 151 1 Y 1 B PRO 369 ? B PRO 396 152 1 Y 1 B VAL 370 ? B VAL 397 153 1 Y 1 B ASP 371 ? B ASP 398 154 1 Y 1 B THR 372 ? B THR 399 155 1 Y 1 B PHE 373 ? B PHE 400 156 1 Y 1 B LEU 374 ? B LEU 401 157 1 Y 1 B ARG 375 ? B ARG 402 158 1 Y 1 B GLY 376 ? B GLY 403 159 1 Y 1 B HIS 377 ? B HIS 404 160 1 Y 1 B GLU 378 ? B GLU 405 161 1 Y 1 B GLU 379 ? B GLU 406 162 1 Y 1 B SER 380 ? B SER 407 163 1 Y 1 B GLY 381 ? B GLY 408 164 1 Y 1 B ASP 382 ? B ASP 409 165 1 Y 1 B ARG 383 ? B ARG 410 166 1 Y 1 B PHE 384 ? B PHE 411 167 1 Y 1 B SER 385 ? B SER 412 168 1 Y 1 B ASN 386 ? B ASN 413 169 1 Y 1 B SER 387 ? B SER 414 170 1 Y 1 B SER 388 ? B SER 415 171 1 Y 1 B THR 389 ? B THR 416 172 1 Y 1 B ALA 390 ? B ALA 417 173 1 Y 1 B GLY 532 ? B GLY 559 174 1 Y 1 B PHE 533 ? B PHE 560 175 1 Y 1 B SER 534 ? B SER 561 176 1 Y 1 B ARG 535 ? B ARG 562 177 1 Y 1 B GLU 536 ? B GLU 563 178 1 Y 1 B VAL 537 ? B VAL 564 179 1 Y 1 B PRO 538 ? B PRO 565 180 1 Y 1 B PHE 539 ? B PHE 566 181 1 Y 1 B SER 540 ? B SER 567 182 1 Y 1 B ASN 541 ? B ASN 568 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 CYCLOMETHYLTRYPTOPHAN TCR 3 N-ACETYL-D-GLUCOSAMINE NAG 4 'CHLORIDE ION' CL 5 'BICARBONATE ION' BCT 6 'MAGNESIUM ION' MG 7 water HOH #