data_5EGH # _entry.id 5EGH # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5EGH WWPDB D_1000214865 # _pdbx_database_related.db_name PDB _pdbx_database_related.details . _pdbx_database_related.db_id 5EGE _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5EGH _pdbx_database_status.recvd_initial_deposition_date 2015-10-27 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBJ _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Morita, J.' 1 'Kano, K.' 2 'Kato, K.' 3 'Takita, H.' 4 'Ishitani, R.' 5 'Nishimasu, H.' 6 'Nureki, O.' 7 'Aoki, J.' 8 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country UK _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'Sci Rep' _citation.journal_id_ASTM ? _citation.journal_id_CSD ? _citation.journal_id_ISSN 2045-2322 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 6 _citation.language ? _citation.page_first 20995 _citation.page_last 20995 _citation.title 'Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase' _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1038/srep20995 _citation.pdbx_database_id_PubMed 26888014 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Morita, J.' 1 primary 'Kano, K.' 2 primary 'Kato, K.' 3 primary 'Takita, H.' 4 primary 'Sakagami, H.' 5 primary 'Yamamoto, Y.' 6 primary 'Mihara, E.' 7 primary 'Ueda, H.' 8 primary 'Sato, T.' 9 primary 'Tokuyama, H.' 10 primary 'Arai, H.' 11 primary 'Asou, H.' 12 primary 'Takagi, J.' 13 primary 'Ishitani, R.' 14 primary 'Nishimasu, H.' 15 primary 'Nureki, O.' 16 primary 'Aoki, J.' 17 # _cell.length_a 63.620 _cell.length_b 68.849 _cell.length_c 69.761 _cell.angle_alpha 60.590 _cell.angle_beta 86.990 _cell.angle_gamma 68.100 _cell.entry_id 5EGH _cell.Z_PDB 2 _cell.pdbx_unique_axis ? # _symmetry.space_group_name_H-M 'P 1' _symmetry.entry_id 5EGH _symmetry.Int_Tables_number 1 _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 6' 49598.664 2 3.1.4.-,3.1.4.38 'C393A, C412S' 'UNP residues 1-421' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 11 ? ? ? ? 3 non-polymer man BETA-L-FUCOSE 164.156 2 ? ? ? ? 4 non-polymer syn 'ZINC ION' 65.409 4 ? ? ? ? 5 non-polymer syn 1,2-ETHANEDIOL 62.068 5 ? ? ? ? 6 non-polymer syn PHOSPHOCHOLINE 184.151 2 ? ? ? ? 7 water nat water 18.015 528 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'NPP-6,Choline-specific glycerophosphodiester phosphodiesterase,Glycerophosphocholine cholinephosphodiesterase,GPC-Cpde' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;MAAKLWTFLLGFGLSWVWPASAHRKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMT GRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKTV PTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALRAVDTVLKYMIQWIQDRGLQQDLNVILFSD HGMTDIFWMDKVIELSNYISLDDLQQVKDRGPVVSLWPVPGKHSEIYHKLRTVEHMTVYEKESIPNRFYYKKGKFVSPLT LVADEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGPDFKSNFRAAPIRSVDVYNIMAHVAGITP LPNNGSWSRVVSMLKGQTSSASRENLYFQ ; _entity_poly.pdbx_seq_one_letter_code_can ;MAAKLWTFLLGFGLSWVWPASAHRKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMT GRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKTV PTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALRAVDTVLKYMIQWIQDRGLQQDLNVILFSD HGMTDIFWMDKVIELSNYISLDDLQQVKDRGPVVSLWPVPGKHSEIYHKLRTVEHMTVYEKESIPNRFYYKKGKFVSPLT LVADEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGPDFKSNFRAAPIRSVDVYNIMAHVAGITP LPNNGSWSRVVSMLKGQTSSASRENLYFQ ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 MET n 1 2 ALA n 1 3 ALA n 1 4 LYS n 1 5 LEU n 1 6 TRP n 1 7 THR n 1 8 PHE n 1 9 LEU n 1 10 LEU n 1 11 GLY n 1 12 PHE n 1 13 GLY n 1 14 LEU n 1 15 SER n 1 16 TRP n 1 17 VAL n 1 18 TRP n 1 19 PRO n 1 20 ALA n 1 21 SER n 1 22 ALA n 1 23 HIS n 1 24 ARG n 1 25 LYS n 1 26 LEU n 1 27 LEU n 1 28 VAL n 1 29 LEU n 1 30 LEU n 1 31 LEU n 1 32 ASP n 1 33 GLY n 1 34 PHE n 1 35 ARG n 1 36 SER n 1 37 ASP n 1 38 TYR n 1 39 ILE n 1 40 SER n 1 41 GLU n 1 42 ASP n 1 43 ALA n 1 44 LEU n 1 45 ALA n 1 46 SER n 1 47 LEU n 1 48 PRO n 1 49 GLY n 1 50 PHE n 1 51 ARG n 1 52 GLU n 1 53 ILE n 1 54 VAL n 1 55 ASN n 1 56 ARG n 1 57 GLY n 1 58 VAL n 1 59 LYS n 1 60 VAL n 1 61 ASP n 1 62 TYR n 1 63 LEU n 1 64 THR n 1 65 PRO n 1 66 ASP n 1 67 PHE n 1 68 PRO n 1 69 SER n 1 70 LEU n 1 71 SER n 1 72 TYR n 1 73 PRO n 1 74 ASN n 1 75 TYR n 1 76 TYR n 1 77 THR n 1 78 LEU n 1 79 MET n 1 80 THR n 1 81 GLY n 1 82 ARG n 1 83 HIS n 1 84 CYS n 1 85 GLU n 1 86 VAL n 1 87 HIS n 1 88 GLN n 1 89 MET n 1 90 ILE n 1 91 GLY n 1 92 ASN n 1 93 TYR n 1 94 MET n 1 95 TRP n 1 96 ASP n 1 97 PRO n 1 98 ARG n 1 99 THR n 1 100 ASN n 1 101 LYS n 1 102 SER n 1 103 PHE n 1 104 ASP n 1 105 ILE n 1 106 GLY n 1 107 VAL n 1 108 ASN n 1 109 ARG n 1 110 ASP n 1 111 SER n 1 112 LEU n 1 113 MET n 1 114 PRO n 1 115 LEU n 1 116 TRP n 1 117 TRP n 1 118 ASN n 1 119 GLY n 1 120 SER n 1 121 GLU n 1 122 PRO n 1 123 LEU n 1 124 TRP n 1 125 ILE n 1 126 THR n 1 127 LEU n 1 128 MET n 1 129 LYS n 1 130 ALA n 1 131 ARG n 1 132 ARG n 1 133 LYS n 1 134 VAL n 1 135 TYR n 1 136 MET n 1 137 TYR n 1 138 TYR n 1 139 TRP n 1 140 PRO n 1 141 GLY n 1 142 CYS n 1 143 GLU n 1 144 VAL n 1 145 GLU n 1 146 ILE n 1 147 LEU n 1 148 GLY n 1 149 VAL n 1 150 ARG n 1 151 PRO n 1 152 THR n 1 153 TYR n 1 154 CYS n 1 155 LEU n 1 156 GLU n 1 157 TYR n 1 158 LYS n 1 159 THR n 1 160 VAL n 1 161 PRO n 1 162 THR n 1 163 ASP n 1 164 ILE n 1 165 ASN n 1 166 PHE n 1 167 ALA n 1 168 ASN n 1 169 ALA n 1 170 VAL n 1 171 SER n 1 172 ASP n 1 173 ALA n 1 174 LEU n 1 175 ASP n 1 176 SER n 1 177 LEU n 1 178 LYS n 1 179 SER n 1 180 GLY n 1 181 ARG n 1 182 ALA n 1 183 ASP n 1 184 LEU n 1 185 ALA n 1 186 ALA n 1 187 ILE n 1 188 TYR n 1 189 HIS n 1 190 GLU n 1 191 ARG n 1 192 ILE n 1 193 ASP n 1 194 VAL n 1 195 GLU n 1 196 GLY n 1 197 HIS n 1 198 HIS n 1 199 TYR n 1 200 GLY n 1 201 PRO n 1 202 SER n 1 203 SER n 1 204 PRO n 1 205 GLN n 1 206 ARG n 1 207 LYS n 1 208 ASP n 1 209 ALA n 1 210 LEU n 1 211 ARG n 1 212 ALA n 1 213 VAL n 1 214 ASP n 1 215 THR n 1 216 VAL n 1 217 LEU n 1 218 LYS n 1 219 TYR n 1 220 MET n 1 221 ILE n 1 222 GLN n 1 223 TRP n 1 224 ILE n 1 225 GLN n 1 226 ASP n 1 227 ARG n 1 228 GLY n 1 229 LEU n 1 230 GLN n 1 231 GLN n 1 232 ASP n 1 233 LEU n 1 234 ASN n 1 235 VAL n 1 236 ILE n 1 237 LEU n 1 238 PHE n 1 239 SER n 1 240 ASP n 1 241 HIS n 1 242 GLY n 1 243 MET n 1 244 THR n 1 245 ASP n 1 246 ILE n 1 247 PHE n 1 248 TRP n 1 249 MET n 1 250 ASP n 1 251 LYS n 1 252 VAL n 1 253 ILE n 1 254 GLU n 1 255 LEU n 1 256 SER n 1 257 ASN n 1 258 TYR n 1 259 ILE n 1 260 SER n 1 261 LEU n 1 262 ASP n 1 263 ASP n 1 264 LEU n 1 265 GLN n 1 266 GLN n 1 267 VAL n 1 268 LYS n 1 269 ASP n 1 270 ARG n 1 271 GLY n 1 272 PRO n 1 273 VAL n 1 274 VAL n 1 275 SER n 1 276 LEU n 1 277 TRP n 1 278 PRO n 1 279 VAL n 1 280 PRO n 1 281 GLY n 1 282 LYS n 1 283 HIS n 1 284 SER n 1 285 GLU n 1 286 ILE n 1 287 TYR n 1 288 HIS n 1 289 LYS n 1 290 LEU n 1 291 ARG n 1 292 THR n 1 293 VAL n 1 294 GLU n 1 295 HIS n 1 296 MET n 1 297 THR n 1 298 VAL n 1 299 TYR n 1 300 GLU n 1 301 LYS n 1 302 GLU n 1 303 SER n 1 304 ILE n 1 305 PRO n 1 306 ASN n 1 307 ARG n 1 308 PHE n 1 309 TYR n 1 310 TYR n 1 311 LYS n 1 312 LYS n 1 313 GLY n 1 314 LYS n 1 315 PHE n 1 316 VAL n 1 317 SER n 1 318 PRO n 1 319 LEU n 1 320 THR n 1 321 LEU n 1 322 VAL n 1 323 ALA n 1 324 ASP n 1 325 GLU n 1 326 GLY n 1 327 TRP n 1 328 PHE n 1 329 ILE n 1 330 ALA n 1 331 GLU n 1 332 SER n 1 333 ARG n 1 334 GLU n 1 335 MET n 1 336 LEU n 1 337 PRO n 1 338 PHE n 1 339 TRP n 1 340 MET n 1 341 ASN n 1 342 SER n 1 343 THR n 1 344 GLY n 1 345 LYS n 1 346 ARG n 1 347 GLU n 1 348 GLY n 1 349 TRP n 1 350 GLN n 1 351 ARG n 1 352 GLY n 1 353 TRP n 1 354 HIS n 1 355 GLY n 1 356 TYR n 1 357 ASP n 1 358 ASN n 1 359 GLU n 1 360 LEU n 1 361 MET n 1 362 ASP n 1 363 MET n 1 364 ARG n 1 365 GLY n 1 366 ILE n 1 367 PHE n 1 368 LEU n 1 369 ALA n 1 370 ILE n 1 371 GLY n 1 372 PRO n 1 373 ASP n 1 374 PHE n 1 375 LYS n 1 376 SER n 1 377 ASN n 1 378 PHE n 1 379 ARG n 1 380 ALA n 1 381 ALA n 1 382 PRO n 1 383 ILE n 1 384 ARG n 1 385 SER n 1 386 VAL n 1 387 ASP n 1 388 VAL n 1 389 TYR n 1 390 ASN n 1 391 ILE n 1 392 MET n 1 393 ALA n 1 394 HIS n 1 395 VAL n 1 396 ALA n 1 397 GLY n 1 398 ILE n 1 399 THR n 1 400 PRO n 1 401 LEU n 1 402 PRO n 1 403 ASN n 1 404 ASN n 1 405 GLY n 1 406 SER n 1 407 TRP n 1 408 SER n 1 409 ARG n 1 410 VAL n 1 411 VAL n 1 412 SER n 1 413 MET n 1 414 LEU n 1 415 LYS n 1 416 GLY n 1 417 GLN n 1 418 THR n 1 419 SER n 1 420 SER n 1 421 ALA n 1 422 SER n 1 423 ARG n 1 424 GLU n 1 425 ASN n 1 426 LEU n 1 427 TYR n 1 428 PHE n 1 429 GLN n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 429 _entity_src_gen.gene_src_common_name Mouse _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene Enpp6 _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Mus musculus' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 10090 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 9606 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line HEK293T _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.db_code ENPP6_MOUSE _struct_ref.db_name UNP _struct_ref.details ? _struct_ref.entity_id 1 _struct_ref.id 1 _struct_ref.seq_align ? _struct_ref.seq_dif ? _struct_ref.pdbx_db_accession Q8BGN3 _struct_ref.pdbx_db_isoform ? _struct_ref.pdbx_seq_one_letter_code ;MAAKLWTFLLGFGLSWVWPASAHRKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMT GRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKTV PTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALRAVDTVLKYMIQWIQDRGLQQDLNVILFSD HGMTDIFWMDKVIELSNYISLDDLQQVKDRGPVVSLWPVPGKHSEIYHKLRTVEHMTVYEKESIPNRFYYKKGKFVSPLT LVADEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGPDFKSNFRAAPIRSVDVYNIMCHVAGITP LPNNGSWSRVVCMLKGQTSSA ; _struct_ref.pdbx_align_begin 1 _struct_ref.pdbx_align_end ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5EGH A 1 ? 421 ? Q8BGN3 1 ? 421 ? 1 421 2 1 5EGH B 1 ? 421 ? Q8BGN3 1 ? 421 ? 1 421 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 5EGH ALA A 393 ? UNP Q8BGN3 CYS 393 'engineered mutation' 393 1 1 5EGH SER A 412 ? UNP Q8BGN3 CYS 412 'engineered mutation' 412 2 1 5EGH SER A 422 ? UNP Q8BGN3 ? ? 'expression tag' 422 3 1 5EGH ARG A 423 ? UNP Q8BGN3 ? ? 'expression tag' 423 4 1 5EGH GLU A 424 ? UNP Q8BGN3 ? ? 'expression tag' 424 5 1 5EGH ASN A 425 ? UNP Q8BGN3 ? ? 'expression tag' 425 6 1 5EGH LEU A 426 ? UNP Q8BGN3 ? ? 'expression tag' 426 7 1 5EGH TYR A 427 ? UNP Q8BGN3 ? ? 'expression tag' 427 8 1 5EGH PHE A 428 ? UNP Q8BGN3 ? ? 'expression tag' 428 9 1 5EGH GLN A 429 ? UNP Q8BGN3 ? ? 'expression tag' 429 10 2 5EGH ALA B 393 ? UNP Q8BGN3 CYS 393 'engineered mutation' 393 11 2 5EGH SER B 412 ? UNP Q8BGN3 CYS 412 'engineered mutation' 412 12 2 5EGH SER B 422 ? UNP Q8BGN3 ? ? 'expression tag' 422 13 2 5EGH ARG B 423 ? UNP Q8BGN3 ? ? 'expression tag' 423 14 2 5EGH GLU B 424 ? UNP Q8BGN3 ? ? 'expression tag' 424 15 2 5EGH ASN B 425 ? UNP Q8BGN3 ? ? 'expression tag' 425 16 2 5EGH LEU B 426 ? UNP Q8BGN3 ? ? 'expression tag' 426 17 2 5EGH TYR B 427 ? UNP Q8BGN3 ? ? 'expression tag' 427 18 2 5EGH PHE B 428 ? UNP Q8BGN3 ? ? 'expression tag' 428 19 2 5EGH GLN B 429 ? UNP Q8BGN3 ? ? 'expression tag' 429 20 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 EDO non-polymer . 1,2-ETHANEDIOL 'ETHYLENE GLYCOL' 'C2 H6 O2' 62.068 FUL L-saccharide . BETA-L-FUCOSE 6-DEOXY-BETA-L-GALACTOSE 'C6 H12 O5' 164.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PC non-polymer . PHOSPHOCHOLINE ? 'C5 H15 N O4 P 1' 184.151 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5EGH _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.46 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 49.94 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details 'sodium acetate, ammonium chloride, PEG 6000, zinc sulfate' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector PIXEL _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'PSI PILATUS 6M' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2013-09-05 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.278 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'SLS BEAMLINE X06SA' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 1.278 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline X06SA _diffrn_source.pdbx_synchrotron_site SLS # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5EGH _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 1.8 _reflns.d_resolution_low 50.0 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 81806 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 94 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 3.5 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 12.8 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high . _reflns_shell.d_res_low ? _reflns_shell.number_measured_obs ? _reflns_shell.number_measured_all ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_rejects 0 _reflns_shell.Rmerge_I_obs ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_redundancy ? _reflns_shell.percent_possible_obs ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.meanI_over_sigI_all ? _reflns_shell.percent_possible_all ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_CC_half ? # _refine.entry_id 5EGH _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_d_res_high 1.8030 _refine.ls_d_res_low 45.6340 _refine.pdbx_ls_sigma_F 1.970 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_percent_reflns_obs 93.9400 _refine.ls_number_reflns_obs 81791 _refine.ls_number_reflns_all ? _refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' _refine.ls_matrix_type ? _refine.pdbx_R_Free_selection_details ? _refine.details ? _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.1766 _refine.ls_R_factor_R_work 0.1748 _refine.ls_wR_factor_R_work ? _refine.ls_R_factor_R_free 0.2111 _refine.ls_wR_factor_R_free ? _refine.ls_percent_reflns_R_free 5.0000 _refine.ls_number_reflns_R_free 4090 _refine.ls_number_reflns_R_work 77701 _refine.ls_R_factor_R_free_error ? _refine.B_iso_mean 32.8955 _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.pdbx_isotropic_thermal_model ? _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.overall_SU_R_free ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.2300 _refine.overall_SU_B ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.pdbx_solvent_vdw_probe_radii 1.1100 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.9000 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.overall_FOM_work_R_set ? _refine.B_iso_max 89.810 _refine.B_iso_min 12.670 _refine.pdbx_overall_phase_error 22.2000 _refine.occupancy_max ? _refine.occupancy_min ? _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_R_factor_R_free_error_details ? # _refine_hist.cycle_id final _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.d_res_high 1.8030 _refine_hist.d_res_low 45.6340 _refine_hist.pdbx_number_atoms_ligand 220 _refine_hist.number_atoms_solvent 528 _refine_hist.number_atoms_total 7139 _refine_hist.pdbx_number_residues_total 785 _refine_hist.pdbx_B_iso_mean_ligand 50.45 _refine_hist.pdbx_B_iso_mean_solvent 38.35 _refine_hist.pdbx_number_atoms_protein 6391 _refine_hist.pdbx_number_atoms_nucleic_acid 0 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' f_bond_d 6859 0.007 ? ? ? 'X-RAY DIFFRACTION' f_angle_d 9349 0.895 ? ? ? 'X-RAY DIFFRACTION' f_chiral_restr 1014 0.056 ? ? ? 'X-RAY DIFFRACTION' f_plane_restr 1172 0.005 ? ? ? 'X-RAY DIFFRACTION' f_dihedral_angle_d 4044 12.545 ? ? ? # loop_ _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.percent_reflns_obs _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_all _refine_ls_shell.R_factor_R_work _refine_ls_shell.R_factor_R_free _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.number_reflns_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.pdbx_refine_id _refine_ls_shell.R_factor_obs 1.8032 1.8244 29 77.0000 2213 . 0.3453 0.3730 . 117 . 2330 . 'X-RAY DIFFRACTION' . 1.8244 1.8466 29 93.0000 2617 . 0.3208 0.3275 . 138 . 2755 . 'X-RAY DIFFRACTION' . 1.8466 1.8700 29 92.0000 2666 . 0.2849 0.3358 . 140 . 2806 . 'X-RAY DIFFRACTION' . 1.8700 1.8946 29 92.0000 2595 . 0.2766 0.3233 . 137 . 2732 . 'X-RAY DIFFRACTION' . 1.8946 1.9206 29 92.0000 2637 . 0.2391 0.3032 . 137 . 2774 . 'X-RAY DIFFRACTION' . 1.9206 1.9480 29 93.0000 2684 . 0.2284 0.2649 . 142 . 2826 . 'X-RAY DIFFRACTION' . 1.9480 1.9771 29 93.0000 2623 . 0.2138 0.2429 . 138 . 2761 . 'X-RAY DIFFRACTION' . 1.9771 2.0080 29 93.0000 2684 . 0.2037 0.2395 . 141 . 2825 . 'X-RAY DIFFRACTION' . 2.0080 2.0409 29 94.0000 2636 . 0.1917 0.2466 . 139 . 2775 . 'X-RAY DIFFRACTION' . 2.0409 2.0761 29 93.0000 2645 . 0.1917 0.2331 . 139 . 2784 . 'X-RAY DIFFRACTION' . 2.0761 2.1138 29 94.0000 2723 . 0.1890 0.2366 . 143 . 2866 . 'X-RAY DIFFRACTION' . 2.1138 2.1545 29 95.0000 2673 . 0.1943 0.2367 . 141 . 2814 . 'X-RAY DIFFRACTION' . 2.1545 2.1985 29 94.0000 2702 . 0.1924 0.2222 . 142 . 2844 . 'X-RAY DIFFRACTION' . 2.1985 2.2463 29 95.0000 2723 . 0.1854 0.2275 . 144 . 2867 . 'X-RAY DIFFRACTION' . 2.2463 2.2985 29 95.0000 2691 . 0.1829 0.2409 . 141 . 2832 . 'X-RAY DIFFRACTION' . 2.2985 2.3560 29 95.0000 2696 . 0.1858 0.2133 . 142 . 2838 . 'X-RAY DIFFRACTION' . 2.3560 2.4197 29 95.0000 2729 . 0.1799 0.1946 . 144 . 2873 . 'X-RAY DIFFRACTION' . 2.4197 2.4909 29 95.0000 2715 . 0.1875 0.2561 . 143 . 2858 . 'X-RAY DIFFRACTION' . 2.4909 2.5713 29 95.0000 2716 . 0.1835 0.2190 . 143 . 2859 . 'X-RAY DIFFRACTION' . 2.5713 2.6632 29 96.0000 2727 . 0.1765 0.2433 . 143 . 2870 . 'X-RAY DIFFRACTION' . 2.6632 2.7698 29 96.0000 2760 . 0.1795 0.2234 . 145 . 2905 . 'X-RAY DIFFRACTION' . 2.7698 2.8958 29 96.0000 2737 . 0.1828 0.2140 . 144 . 2881 . 'X-RAY DIFFRACTION' . 2.8958 3.0485 29 96.0000 2721 . 0.1819 0.2333 . 144 . 2865 . 'X-RAY DIFFRACTION' . 3.0485 3.2394 29 95.0000 2686 . 0.1731 0.1975 . 141 . 2827 . 'X-RAY DIFFRACTION' . 3.2394 3.4895 29 95.0000 2717 . 0.1624 0.1960 . 143 . 2860 . 'X-RAY DIFFRACTION' . 3.4895 3.8405 29 96.0000 2742 . 0.1545 0.1925 . 144 . 2886 . 'X-RAY DIFFRACTION' . 3.8405 4.3958 29 96.0000 2750 . 0.1390 0.1629 . 145 . 2895 . 'X-RAY DIFFRACTION' . 4.3958 5.5367 29 96.0000 2713 . 0.1341 0.1665 . 143 . 2856 . 'X-RAY DIFFRACTION' . 5.5367 45.6485 29 97.0000 2780 . 0.1626 0.1835 . 147 . 2927 . 'X-RAY DIFFRACTION' . # _struct.entry_id 5EGH _struct.title 'Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase in complex with phosphocholine' _struct.pdbx_descriptor 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E.C.3.1.4.-,3.1.4.38)' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5EGH _struct_keywords.text 'Choline metabolism, Phosphodiesterase, HYDROLASE' _struct_keywords.pdbx_keywords HYDROLASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 2 ? E N N 2 ? F N N 2 ? G N N 3 ? H N N 2 ? I N N 2 ? J N N 4 ? K N N 4 ? L N N 5 ? M N N 5 ? N N N 6 ? O N N 5 ? P N N 2 ? Q N N 2 ? R N N 3 ? S N N 2 ? T N N 2 ? U N N 2 ? V N N 4 ? W N N 4 ? X N N 5 ? Y N N 6 ? Z N N 5 ? AA N N 7 ? BA N N 7 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 ARG A 35 ? ILE A 39 ? ARG A 35 ILE A 39 5 ? 5 HELX_P HELX_P2 AA2 SER A 40 ? ALA A 45 ? SER A 40 ALA A 45 1 ? 6 HELX_P HELX_P3 AA3 LEU A 47 ? GLY A 57 ? LEU A 47 GLY A 57 1 ? 11 HELX_P HELX_P4 AA4 LEU A 70 ? GLY A 81 ? LEU A 70 GLY A 81 1 ? 12 HELX_P HELX_P5 AA5 HIS A 83 ? GLN A 88 ? HIS A 83 GLN A 88 1 ? 6 HELX_P HELX_P6 AA6 ASN A 108 ? TRP A 117 ? ASN A 108 TRP A 117 5 ? 10 HELX_P HELX_P7 AA7 PRO A 122 ? ALA A 130 ? PRO A 122 ALA A 130 1 ? 9 HELX_P HELX_P8 AA8 THR A 162 ? SER A 179 ? THR A 162 SER A 179 1 ? 18 HELX_P HELX_P9 AA9 GLU A 190 ? GLY A 200 ? GLU A 190 GLY A 200 1 ? 11 HELX_P HELX_P10 AB1 SER A 203 ? ARG A 227 ? SER A 203 ARG A 227 1 ? 25 HELX_P HELX_P11 AB2 SER A 256 ? TYR A 258 ? SER A 256 TYR A 258 5 ? 3 HELX_P HELX_P12 AB3 SER A 260 ? ASP A 262 ? SER A 260 ASP A 262 5 ? 3 HELX_P HELX_P13 AB4 LYS A 282 ? ARG A 291 ? LYS A 282 ARG A 291 1 ? 10 HELX_P HELX_P14 AB5 GLU A 302 ? ILE A 304 ? GLU A 302 ILE A 304 5 ? 3 HELX_P HELX_P15 AB6 PRO A 305 ? TYR A 309 ? PRO A 305 TYR A 309 5 ? 5 HELX_P HELX_P16 AB7 SER A 332 ? LEU A 336 ? SER A 332 LEU A 336 5 ? 5 HELX_P HELX_P17 AB8 LEU A 360 ? ARG A 364 ? LEU A 360 ARG A 364 5 ? 5 HELX_P HELX_P18 AB9 ASP A 387 ? GLY A 397 ? ASP A 387 GLY A 397 1 ? 11 HELX_P HELX_P19 AC1 VAL A 410 ? LEU A 414 ? VAL A 410 LEU A 414 5 ? 5 HELX_P HELX_P20 AC2 ARG B 35 ? ILE B 39 ? ARG B 35 ILE B 39 5 ? 5 HELX_P HELX_P21 AC3 SER B 40 ? ALA B 45 ? SER B 40 ALA B 45 1 ? 6 HELX_P HELX_P22 AC4 LEU B 47 ? GLY B 57 ? LEU B 47 GLY B 57 1 ? 11 HELX_P HELX_P23 AC5 LEU B 70 ? GLY B 81 ? LEU B 70 GLY B 81 1 ? 12 HELX_P HELX_P24 AC6 HIS B 83 ? GLN B 88 ? HIS B 83 GLN B 88 1 ? 6 HELX_P HELX_P25 AC7 ASN B 108 ? TRP B 117 ? ASN B 108 TRP B 117 5 ? 10 HELX_P HELX_P26 AC8 PRO B 122 ? ALA B 130 ? PRO B 122 ALA B 130 1 ? 9 HELX_P HELX_P27 AC9 THR B 162 ? SER B 179 ? THR B 162 SER B 179 1 ? 18 HELX_P HELX_P28 AD1 GLU B 190 ? GLY B 200 ? GLU B 190 GLY B 200 1 ? 11 HELX_P HELX_P29 AD2 SER B 203 ? ARG B 227 ? SER B 203 ARG B 227 1 ? 25 HELX_P HELX_P30 AD3 LEU B 229 ? GLN B 231 ? LEU B 229 GLN B 231 5 ? 3 HELX_P HELX_P31 AD4 SER B 256 ? TYR B 258 ? SER B 256 TYR B 258 5 ? 3 HELX_P HELX_P32 AD5 SER B 260 ? ASP B 262 ? SER B 260 ASP B 262 5 ? 3 HELX_P HELX_P33 AD6 LYS B 282 ? ARG B 291 ? LYS B 282 ARG B 291 1 ? 10 HELX_P HELX_P34 AD7 GLU B 302 ? ILE B 304 ? GLU B 302 ILE B 304 5 ? 3 HELX_P HELX_P35 AD8 PRO B 305 ? TYR B 309 ? PRO B 305 TYR B 309 5 ? 5 HELX_P HELX_P36 AD9 SER B 332 ? LEU B 336 ? SER B 332 LEU B 336 5 ? 5 HELX_P HELX_P37 AE1 LEU B 360 ? ARG B 364 ? LEU B 360 ARG B 364 5 ? 5 HELX_P HELX_P38 AE2 ASP B 387 ? GLY B 397 ? ASP B 387 GLY B 397 1 ? 11 HELX_P HELX_P39 AE3 VAL B 410 ? LEU B 414 ? VAL B 410 LEU B 414 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 142 SG ? ? ? 1_555 A CYS 154 SG ? ? A CYS 142 A CYS 154 1_555 ? ? ? ? ? ? ? 2.085 ? disulf2 disulf ? ? B CYS 142 SG ? ? ? 1_555 B CYS 154 SG ? ? B CYS 142 B CYS 154 1_555 ? ? ? ? ? ? ? 2.096 ? metalc1 metalc ? ? A ASP 32 OD1 ? ? ? 1_555 K ZN . ZN ? ? A ASP 32 A ZN 509 1_555 ? ? ? ? ? ? ? 1.977 ? metalc2 metalc ? ? A SER 71 OG ? ? ? 1_555 K ZN . ZN ? ? A SER 71 A ZN 509 1_555 ? ? ? ? ? ? ? 2.368 ? covale1 covale one ? A ASN 118 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 118 A NAG 501 1_555 ? ? ? ? ? ? ? 1.436 ? metalc3 metalc ? ? A ASP 193 OD1 ? ? ? 1_555 J ZN . ZN ? ? A ASP 193 A ZN 508 1_555 ? ? ? ? ? ? ? 2.573 ? metalc4 metalc ? ? A ASP 193 OD2 ? ? ? 1_555 J ZN . ZN ? ? A ASP 193 A ZN 508 1_555 ? ? ? ? ? ? ? 2.257 ? metalc5 metalc ? ? A HIS 197 NE2 ? ? ? 1_555 J ZN . ZN ? ? A HIS 197 A ZN 508 1_555 ? ? ? ? ? ? ? 2.072 ? metalc6 metalc ? ? A ASP 240 OD2 ? ? ? 1_555 K ZN . ZN ? ? A ASP 240 A ZN 509 1_555 ? ? ? ? ? ? ? 2.119 ? metalc7 metalc ? ? A HIS 241 NE2 ? ? ? 1_555 K ZN . ZN ? ? A HIS 241 A ZN 509 1_555 ? ? ? ? ? ? ? 2.081 ? covale2 covale one ? A ASN 341 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 341 A NAG 503 1_555 ? ? ? ? ? ? ? 1.440 ? metalc8 metalc ? ? A HIS 354 NE2 ? ? ? 1_555 J ZN . ZN ? ? A HIS 354 A ZN 508 1_555 ? ? ? ? ? ? ? 1.999 ? covale3 covale one ? A ASN 404 ND2 ? ? ? 1_555 H NAG . C1 ? ? A ASN 404 A NAG 506 1_555 ? ? ? ? ? ? ? 1.438 ? metalc9 metalc ? ? B ASP 32 OD1 ? ? ? 1_555 V ZN . ZN ? ? B ASP 32 B ZN 507 1_555 ? ? ? ? ? ? ? 1.936 ? metalc10 metalc ? ? B SER 71 OG ? ? ? 1_555 V ZN . ZN ? ? B SER 71 B ZN 507 1_555 ? ? ? ? ? ? ? 2.305 ? covale4 covale one ? B ASN 118 ND2 ? ? ? 1_555 P NAG . C1 ? ? B ASN 118 B NAG 501 1_555 ? ? ? ? ? ? ? 1.444 ? metalc11 metalc ? ? B ASP 193 OD1 ? ? ? 1_555 W ZN . ZN ? ? B ASP 193 B ZN 508 1_555 ? ? ? ? ? ? ? 2.493 ? metalc12 metalc ? ? B ASP 193 OD2 ? ? ? 1_555 W ZN . ZN ? ? B ASP 193 B ZN 508 1_555 ? ? ? ? ? ? ? 2.271 ? metalc13 metalc ? ? B HIS 197 NE2 ? ? ? 1_555 W ZN . ZN ? ? B HIS 197 B ZN 508 1_555 ? ? ? ? ? ? ? 2.140 ? metalc14 metalc ? ? B ASP 240 OD2 ? ? ? 1_555 V ZN . ZN ? ? B ASP 240 B ZN 507 1_555 ? ? ? ? ? ? ? 2.068 ? metalc15 metalc ? ? B HIS 241 NE2 ? ? ? 1_555 V ZN . ZN ? ? B HIS 241 B ZN 507 1_555 ? ? ? ? ? ? ? 2.079 ? covale5 covale one ? B ASN 341 ND2 ? ? ? 1_555 Q NAG . C1 ? ? B ASN 341 B NAG 502 1_555 ? ? ? ? ? ? ? 1.433 ? metalc16 metalc ? ? B HIS 354 NE2 ? ? ? 1_555 W ZN . ZN ? ? B HIS 354 B ZN 508 1_555 ? ? ? ? ? ? ? 2.061 ? covale6 covale one ? B ASN 404 ND2 ? ? ? 1_555 T NAG . C1 ? ? B ASN 404 B NAG 505 1_555 ? ? ? ? ? ? ? 1.444 ? covale7 covale both ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? A NAG 501 A NAG 502 1_555 ? ? ? ? ? ? ? 1.435 ? covale8 covale both ? E NAG . O4 ? ? ? 1_555 F NAG . C1 ? ? A NAG 503 A NAG 504 1_555 ? ? ? ? ? ? ? 1.450 ? covale9 covale one ? E NAG . O6 ? ? ? 1_555 G FUL . C1 ? ? A NAG 503 A FUL 505 1_555 ? ? ? ? ? ? ? 1.452 ? covale10 covale both ? H NAG . O4 ? ? ? 1_555 I NAG . C1 ? ? A NAG 506 A NAG 507 1_555 ? ? ? ? ? ? ? 1.441 ? metalc17 metalc ? ? J ZN . ZN ? ? ? 1_555 N PC . O1 ? ? A ZN 508 A PC 512 1_555 ? ? ? ? ? ? ? 2.101 ? metalc18 metalc ? ? K ZN . ZN ? ? ? 1_555 N PC . O3 ? ? A ZN 509 A PC 512 1_555 ? ? ? ? ? ? ? 1.965 ? covale11 covale both ? Q NAG . O4 ? ? ? 1_555 S NAG . C1 ? ? B NAG 502 B NAG 504 1_555 ? ? ? ? ? ? ? 1.437 ? covale12 covale one ? Q NAG . O6 ? ? ? 1_555 R FUL . C1 ? ? B NAG 502 B FUL 503 1_555 ? ? ? ? ? ? ? 1.435 ? covale13 covale both ? T NAG . O4 ? ? ? 1_555 U NAG . C1 ? ? B NAG 505 B NAG 506 1_555 ? ? ? ? ? ? ? 1.441 ? metalc19 metalc ? ? V ZN . ZN ? ? ? 1_555 Y PC . O4 ? ? B ZN 507 B PC 510 1_555 ? ? ? ? ? ? ? 2.014 ? metalc20 metalc ? ? W ZN . ZN ? ? ? 1_555 Y PC . O3 ? ? B ZN 508 B PC 510 1_555 ? ? ? ? ? ? ? 2.105 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 67 A . ? PHE 67 A PRO 68 A ? PRO 68 A 1 -4.04 2 TRP 248 A . ? TRP 248 A MET 249 A ? MET 249 A 1 -2.42 3 PHE 67 B . ? PHE 67 B PRO 68 B ? PRO 68 B 1 -3.38 4 TRP 248 B . ? TRP 248 B MET 249 B ? MET 249 B 1 -2.11 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 8 ? AA2 ? 2 ? AA3 ? 2 ? AA4 ? 2 ? AA5 ? 2 ? AA6 ? 4 ? AA7 ? 8 ? AA8 ? 2 ? AA9 ? 2 ? AB1 ? 2 ? AB2 ? 2 ? AB3 ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? parallel AA1 2 3 ? parallel AA1 3 4 ? parallel AA1 4 5 ? parallel AA1 5 6 ? anti-parallel AA1 6 7 ? anti-parallel AA1 7 8 ? parallel AA2 1 2 ? parallel AA3 1 2 ? anti-parallel AA4 1 2 ? anti-parallel AA5 1 2 ? parallel AA6 1 2 ? anti-parallel AA6 2 3 ? anti-parallel AA6 3 4 ? anti-parallel AA7 1 2 ? parallel AA7 2 3 ? parallel AA7 3 4 ? parallel AA7 4 5 ? parallel AA7 5 6 ? anti-parallel AA7 6 7 ? anti-parallel AA7 7 8 ? parallel AA8 1 2 ? parallel AA9 1 2 ? anti-parallel AB1 1 2 ? anti-parallel AB2 1 2 ? parallel AB3 1 2 ? anti-parallel AB3 2 3 ? anti-parallel AB3 3 4 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 TYR A 153 ? LEU A 155 ? TYR A 153 LEU A 155 AA1 2 VAL A 134 ? TYR A 137 ? VAL A 134 TYR A 137 AA1 3 LEU A 184 ? HIS A 189 ? LEU A 184 HIS A 189 AA1 4 LYS A 25 ? LEU A 31 ? LYS A 25 LEU A 31 AA1 5 LEU A 233 ? PHE A 238 ? LEU A 233 PHE A 238 AA1 6 PHE A 367 ? ILE A 370 ? PHE A 367 ILE A 370 AA1 7 VAL A 58 ? VAL A 60 ? VAL A 58 VAL A 60 AA1 8 PHE A 378 ? ALA A 380 ? PHE A 378 ALA A 380 AA2 1 LEU A 63 ? THR A 64 ? LEU A 63 THR A 64 AA2 2 ILE A 383 ? ARG A 384 ? ILE A 383 ARG A 384 AA3 1 TYR A 93 ? ASP A 96 ? TYR A 93 ASP A 96 AA3 2 LYS A 101 ? ASP A 104 ? LYS A 101 ASP A 104 AA4 1 THR A 244 ? ASP A 245 ? THR A 244 ASP A 245 AA4 2 GLY A 352 ? TRP A 353 ? GLY A 352 TRP A 353 AA5 1 VAL A 252 ? GLU A 254 ? VAL A 252 GLU A 254 AA5 2 PHE A 328 ? ALA A 330 ? PHE A 328 ALA A 330 AA6 1 LEU A 264 ? LYS A 268 ? LEU A 264 LYS A 268 AA6 2 VAL A 273 ? PRO A 278 ? VAL A 273 PRO A 278 AA6 3 LEU A 319 ? ALA A 323 ? LEU A 319 ALA A 323 AA6 4 MET A 296 ? GLU A 300 ? MET A 296 GLU A 300 AA7 1 TYR B 153 ? LEU B 155 ? TYR B 153 LEU B 155 AA7 2 VAL B 134 ? TYR B 137 ? VAL B 134 TYR B 137 AA7 3 LEU B 184 ? HIS B 189 ? LEU B 184 HIS B 189 AA7 4 LYS B 25 ? LEU B 31 ? LYS B 25 LEU B 31 AA7 5 LEU B 233 ? PHE B 238 ? LEU B 233 PHE B 238 AA7 6 PHE B 367 ? ILE B 370 ? PHE B 367 ILE B 370 AA7 7 VAL B 58 ? VAL B 60 ? VAL B 58 VAL B 60 AA7 8 PHE B 378 ? ALA B 380 ? PHE B 378 ALA B 380 AA8 1 LEU B 63 ? THR B 64 ? LEU B 63 THR B 64 AA8 2 ILE B 383 ? ARG B 384 ? ILE B 383 ARG B 384 AA9 1 TYR B 93 ? ASP B 96 ? TYR B 93 ASP B 96 AA9 2 LYS B 101 ? ASP B 104 ? LYS B 101 ASP B 104 AB1 1 THR B 244 ? ASP B 245 ? THR B 244 ASP B 245 AB1 2 GLY B 352 ? TRP B 353 ? GLY B 352 TRP B 353 AB2 1 VAL B 252 ? GLU B 254 ? VAL B 252 GLU B 254 AB2 2 PHE B 328 ? ALA B 330 ? PHE B 328 ALA B 330 AB3 1 LEU B 264 ? LYS B 268 ? LEU B 264 LYS B 268 AB3 2 VAL B 273 ? PRO B 278 ? VAL B 273 PRO B 278 AB3 3 LEU B 319 ? ALA B 323 ? LEU B 319 ALA B 323 AB3 4 MET B 296 ? GLU B 300 ? MET B 296 GLU B 300 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 O LEU A 155 ? O LEU A 155 N MET A 136 ? N MET A 136 AA1 2 3 N TYR A 137 ? N TYR A 137 O ALA A 186 ? O ALA A 186 AA1 3 4 O ALA A 185 ? O ALA A 185 N VAL A 28 ? N VAL A 28 AA1 4 5 N LEU A 29 ? N LEU A 29 O ILE A 236 ? O ILE A 236 AA1 5 6 N LEU A 237 ? N LEU A 237 O LEU A 368 ? O LEU A 368 AA1 6 7 O ALA A 369 ? O ALA A 369 N VAL A 58 ? N VAL A 58 AA1 7 8 N LYS A 59 ? N LYS A 59 O PHE A 378 ? O PHE A 378 AA2 1 2 N THR A 64 ? N THR A 64 O ILE A 383 ? O ILE A 383 AA3 1 2 N ASP A 96 ? N ASP A 96 O LYS A 101 ? O LYS A 101 AA4 1 2 N THR A 244 ? N THR A 244 O TRP A 353 ? O TRP A 353 AA5 1 2 N ILE A 253 ? N ILE A 253 O PHE A 328 ? O PHE A 328 AA6 1 2 N GLN A 265 ? N GLN A 265 O TRP A 277 ? O TRP A 277 AA6 2 3 N VAL A 274 ? N VAL A 274 O LEU A 321 ? O LEU A 321 AA6 3 4 O VAL A 322 ? O VAL A 322 N THR A 297 ? N THR A 297 AA7 1 2 O LEU B 155 ? O LEU B 155 N MET B 136 ? N MET B 136 AA7 2 3 N TYR B 137 ? N TYR B 137 O ALA B 186 ? O ALA B 186 AA7 3 4 O ILE B 187 ? O ILE B 187 N VAL B 28 ? N VAL B 28 AA7 4 5 N LEU B 31 ? N LEU B 31 O PHE B 238 ? O PHE B 238 AA7 5 6 N VAL B 235 ? N VAL B 235 O ILE B 370 ? O ILE B 370 AA7 6 7 O ALA B 369 ? O ALA B 369 N VAL B 58 ? N VAL B 58 AA7 7 8 N LYS B 59 ? N LYS B 59 O ALA B 380 ? O ALA B 380 AA8 1 2 N THR B 64 ? N THR B 64 O ILE B 383 ? O ILE B 383 AA9 1 2 N ASP B 96 ? N ASP B 96 O LYS B 101 ? O LYS B 101 AB1 1 2 N THR B 244 ? N THR B 244 O TRP B 353 ? O TRP B 353 AB2 1 2 N ILE B 253 ? N ILE B 253 O PHE B 328 ? O PHE B 328 AB3 1 2 N GLN B 266 ? N GLN B 266 O TRP B 277 ? O TRP B 277 AB3 2 3 N LEU B 276 ? N LEU B 276 O LEU B 319 ? O LEU B 319 AB3 3 4 O THR B 320 ? O THR B 320 N TYR B 299 ? N TYR B 299 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A ZN 508 ? 4 'binding site for residue ZN A 508' AC2 Software A ZN 509 ? 5 'binding site for residue ZN A 509' AC3 Software A EDO 510 ? 5 'binding site for residue EDO A 510' AC4 Software A EDO 511 ? 8 'binding site for residue EDO A 511' AC5 Software A PC 512 ? 13 'binding site for residue PC A 512' AC6 Software A EDO 513 ? 7 'binding site for residue EDO A 513' AC7 Software B ZN 507 ? 5 'binding site for residue ZN B 507' AC8 Software B ZN 508 ? 4 'binding site for residue ZN B 508' AC9 Software B EDO 509 ? 7 'binding site for residue EDO B 509' AD1 Software B PC 510 ? 14 'binding site for residue PC B 510' AD2 Software B EDO 511 ? 6 'binding site for residue EDO B 511' AD3 Software A ASN 118 ? 7 'binding site for Poly-Saccharide residues NAG A 501 through NAG A 502 bound to ASN A 118' AD4 Software A ASN 341 ? 7 'binding site for Poly-Saccharide residues NAG A 503 through FUL A 505 bound to ASN A 341' AD5 Software A ASN 404 ? 7 'binding site for Poly-Saccharide residues NAG A 506 through NAG A 507 bound to ASN A 404' AD6 Software B NAG 501 ? 6 'binding site for Mono-Saccharide NAG B 501 bound to ASN B 118' AD7 Software B ASN 341 ? 7 'binding site for Poly-Saccharide residues NAG B 502 through NAG B 504 bound to ASN B 341' AD8 Software B ASN 404 ? 7 'binding site for Poly-Saccharide residues NAG B 505 through NAG B 506 bound to ASN B 404' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 ASP A 193 ? ASP A 193 . ? 1_555 ? 2 AC1 4 HIS A 197 ? HIS A 197 . ? 1_555 ? 3 AC1 4 HIS A 354 ? HIS A 354 . ? 1_555 ? 4 AC1 4 PC N . ? PC A 512 . ? 1_555 ? 5 AC2 5 ASP A 32 ? ASP A 32 . ? 1_555 ? 6 AC2 5 SER A 71 ? SER A 71 . ? 1_555 ? 7 AC2 5 ASP A 240 ? ASP A 240 . ? 1_555 ? 8 AC2 5 HIS A 241 ? HIS A 241 . ? 1_555 ? 9 AC2 5 PC N . ? PC A 512 . ? 1_555 ? 10 AC3 5 GLU A 85 ? GLU A 85 . ? 1_555 ? 11 AC3 5 ASN A 306 ? ASN A 306 . ? 1_555 ? 12 AC3 5 TYR A 309 ? TYR A 309 . ? 1_555 ? 13 AC3 5 LYS A 311 ? LYS A 311 . ? 1_555 ? 14 AC3 5 HOH AA . ? HOH A 624 . ? 1_555 ? 15 AC4 8 LEU A 70 ? LEU A 70 . ? 1_555 ? 16 AC4 8 GLY A 91 ? GLY A 91 . ? 1_555 ? 17 AC4 8 ASN A 92 ? ASN A 92 . ? 1_555 ? 18 AC4 8 TYR A 93 ? TYR A 93 . ? 1_555 ? 19 AC4 8 ASP A 269 ? ASP A 269 . ? 1_555 ? 20 AC4 8 VAL A 273 ? VAL A 273 . ? 1_555 ? 21 AC4 8 SER A 275 ? SER A 275 . ? 1_555 ? 22 AC4 8 HOH AA . ? HOH A 642 . ? 1_555 ? 23 AC5 13 ASP A 32 ? ASP A 32 . ? 1_555 ? 24 AC5 13 SER A 71 ? SER A 71 . ? 1_555 ? 25 AC5 13 TYR A 72 ? TYR A 72 . ? 1_555 ? 26 AC5 13 TYR A 75 ? TYR A 75 . ? 1_555 ? 27 AC5 13 ASN A 92 ? ASN A 92 . ? 1_555 ? 28 AC5 13 TYR A 188 ? TYR A 188 . ? 1_555 ? 29 AC5 13 GLU A 190 ? GLU A 190 . ? 1_555 ? 30 AC5 13 ASP A 193 ? ASP A 193 . ? 1_555 ? 31 AC5 13 HIS A 197 ? HIS A 197 . ? 1_555 ? 32 AC5 13 HIS A 241 ? HIS A 241 . ? 1_555 ? 33 AC5 13 HIS A 354 ? HIS A 354 . ? 1_555 ? 34 AC5 13 ZN J . ? ZN A 508 . ? 1_555 ? 35 AC5 13 ZN K . ? ZN A 509 . ? 1_555 ? 36 AC6 7 TYR A 72 ? TYR A 72 . ? 1_555 ? 37 AC6 7 GLY A 106 ? GLY A 106 . ? 1_555 ? 38 AC6 7 PRO A 140 ? PRO A 140 . ? 1_555 ? 39 AC6 7 GLY A 141 ? GLY A 141 . ? 1_555 ? 40 AC6 7 GLU A 143 ? GLU A 143 . ? 1_555 ? 41 AC6 7 HOH AA . ? HOH A 639 . ? 1_555 ? 42 AC6 7 ARG B 109 ? ARG B 109 . ? 1_464 ? 43 AC7 5 ASP B 32 ? ASP B 32 . ? 1_555 ? 44 AC7 5 SER B 71 ? SER B 71 . ? 1_555 ? 45 AC7 5 ASP B 240 ? ASP B 240 . ? 1_555 ? 46 AC7 5 HIS B 241 ? HIS B 241 . ? 1_555 ? 47 AC7 5 PC Y . ? PC B 510 . ? 1_555 ? 48 AC8 4 ASP B 193 ? ASP B 193 . ? 1_555 ? 49 AC8 4 HIS B 197 ? HIS B 197 . ? 1_555 ? 50 AC8 4 HIS B 354 ? HIS B 354 . ? 1_555 ? 51 AC8 4 PC Y . ? PC B 510 . ? 1_555 ? 52 AC9 7 GLU B 85 ? GLU B 85 . ? 1_555 ? 53 AC9 7 ASN B 306 ? ASN B 306 . ? 1_555 ? 54 AC9 7 TYR B 309 ? TYR B 309 . ? 1_555 ? 55 AC9 7 TYR B 310 ? TYR B 310 . ? 1_555 ? 56 AC9 7 LYS B 311 ? LYS B 311 . ? 1_555 ? 57 AC9 7 HOH BA . ? HOH B 601 . ? 1_555 ? 58 AC9 7 HOH BA . ? HOH B 610 . ? 1_555 ? 59 AD1 14 ASP B 32 ? ASP B 32 . ? 1_555 ? 60 AD1 14 SER B 71 ? SER B 71 . ? 1_555 ? 61 AD1 14 TYR B 72 ? TYR B 72 . ? 1_555 ? 62 AD1 14 TYR B 75 ? TYR B 75 . ? 1_555 ? 63 AD1 14 ASN B 92 ? ASN B 92 . ? 1_555 ? 64 AD1 14 TYR B 157 ? TYR B 157 . ? 1_555 ? 65 AD1 14 TYR B 188 ? TYR B 188 . ? 1_555 ? 66 AD1 14 GLU B 190 ? GLU B 190 . ? 1_555 ? 67 AD1 14 ASP B 193 ? ASP B 193 . ? 1_555 ? 68 AD1 14 HIS B 197 ? HIS B 197 . ? 1_555 ? 69 AD1 14 HIS B 241 ? HIS B 241 . ? 1_555 ? 70 AD1 14 HIS B 354 ? HIS B 354 . ? 1_555 ? 71 AD1 14 ZN V . ? ZN B 507 . ? 1_555 ? 72 AD1 14 ZN W . ? ZN B 508 . ? 1_555 ? 73 AD2 6 ARG A 109 ? ARG A 109 . ? 1_646 ? 74 AD2 6 TYR B 72 ? TYR B 72 . ? 1_555 ? 75 AD2 6 GLY B 106 ? GLY B 106 . ? 1_555 ? 76 AD2 6 PRO B 140 ? PRO B 140 . ? 1_555 ? 77 AD2 6 GLY B 141 ? GLY B 141 . ? 1_555 ? 78 AD2 6 GLU B 143 ? GLU B 143 . ? 1_555 ? 79 AD3 7 LEU A 115 ? LEU A 115 . ? 1_555 ? 80 AD3 7 ASN A 118 ? ASN A 118 . ? 1_555 ? 81 AD3 7 LEU A 147 ? LEU A 147 . ? 1_555 ? 82 AD3 7 HOH AA . ? HOH A 677 . ? 1_555 ? 83 AD3 7 HOH AA . ? HOH A 736 . ? 1_555 ? 84 AD3 7 HOH AA . ? HOH A 776 . ? 1_555 ? 85 AD3 7 HOH AA . ? HOH A 812 . ? 1_555 ? 86 AD4 7 ASN A 341 ? ASN A 341 . ? 1_555 ? 87 AD4 7 GLU A 347 ? GLU A 347 . ? 1_555 ? 88 AD4 7 GLY A 348 ? GLY A 348 . ? 1_555 ? 89 AD4 7 TRP A 349 ? TRP A 349 . ? 1_555 ? 90 AD4 7 ARG A 351 ? ARG A 351 . ? 1_555 ? 91 AD4 7 HOH AA . ? HOH A 603 . ? 1_555 ? 92 AD4 7 HOH AA . ? HOH A 744 . ? 1_555 ? 93 AD5 7 ARG A 82 ? ARG A 82 . ? 1_555 ? 94 AD5 7 TYR A 309 ? TYR A 309 . ? 1_555 ? 95 AD5 7 PRO A 402 ? PRO A 402 . ? 1_555 ? 96 AD5 7 ASN A 404 ? ASN A 404 . ? 1_555 ? 97 AD5 7 HOH AA . ? HOH A 620 . ? 1_555 ? 98 AD5 7 HOH AA . ? HOH A 693 . ? 1_555 ? 99 AD5 7 HOH AA . ? HOH A 699 . ? 1_555 ? 100 AD6 6 ASN B 118 ? ASN B 118 . ? 1_555 ? 101 AD6 6 LEU B 147 ? LEU B 147 . ? 1_555 ? 102 AD6 6 HOH BA . ? HOH B 602 . ? 1_555 ? 103 AD6 6 HOH BA . ? HOH B 613 . ? 1_555 ? 104 AD6 6 HOH BA . ? HOH B 627 . ? 1_555 ? 105 AD6 6 HOH BA . ? HOH B 707 . ? 1_555 ? 106 AD7 7 ASN B 341 ? ASN B 341 . ? 1_555 ? 107 AD7 7 SER B 342 ? SER B 342 . ? 1_555 ? 108 AD7 7 GLU B 347 ? GLU B 347 . ? 1_555 ? 109 AD7 7 GLY B 348 ? GLY B 348 . ? 1_555 ? 110 AD7 7 TRP B 349 ? TRP B 349 . ? 1_555 ? 111 AD7 7 ARG B 351 ? ARG B 351 . ? 1_555 ? 112 AD7 7 HOH BA . ? HOH B 674 . ? 1_555 ? 113 AD8 7 TYR B 309 ? TYR B 309 . ? 1_555 ? 114 AD8 7 PRO B 402 ? PRO B 402 . ? 1_555 ? 115 AD8 7 ASN B 404 ? ASN B 404 . ? 1_555 ? 116 AD8 7 HOH BA . ? HOH B 609 . ? 1_555 ? 117 AD8 7 HOH BA . ? HOH B 690 . ? 1_555 ? 118 AD8 7 HOH BA . ? HOH B 709 . ? 1_555 ? 119 AD8 7 HOH BA . ? HOH B 728 . ? 1_555 ? # _atom_sites.entry_id 5EGH _atom_sites.fract_transf_matrix[1][1] 0.015718 _atom_sites.fract_transf_matrix[1][2] -0.006318 _atom_sites.fract_transf_matrix[1][3] 0.002775 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.015654 _atom_sites.fract_transf_matrix[2][3] -0.009254 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.016675 _atom_sites.fract_transf_vector[1] 0.000000 _atom_sites.fract_transf_vector[2] 0.000000 _atom_sites.fract_transf_vector[3] 0.000000 # loop_ _atom_type.symbol C N O P S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ARG A 1 24 ? -2.407 23.233 10.635 1.00 36.29 ? 24 ARG A N 1 ATOM 2 C CA . ARG A 1 24 ? -1.732 23.870 9.514 1.00 43.08 ? 24 ARG A CA 1 ATOM 3 C C . ARG A 1 24 ? -1.723 22.978 8.264 1.00 30.51 ? 24 ARG A C 1 ATOM 4 O O . ARG A 1 24 ? -2.373 21.937 8.250 1.00 33.47 ? 24 ARG A O 1 ATOM 5 C CB . ARG A 1 24 ? -0.304 24.243 9.911 1.00 43.27 ? 24 ARG A CB 1 ATOM 6 C CG . ARG A 1 24 ? 0.652 23.073 10.011 1.00 37.18 ? 24 ARG A CG 1 ATOM 7 C CD . ARG A 1 24 ? 1.883 23.453 10.824 1.00 36.17 ? 24 ARG A CD 1 ATOM 8 N NE . ARG A 1 24 ? 1.558 23.573 12.244 1.00 40.40 ? 24 ARG A NE 1 ATOM 9 C CZ . ARG A 1 24 ? 1.452 24.723 12.904 1.00 49.59 ? 24 ARG A CZ 1 ATOM 10 N NH1 . ARG A 1 24 ? 1.142 24.713 14.194 1.00 49.84 ? 24 ARG A NH1 1 ATOM 11 N NH2 . ARG A 1 24 ? 1.667 25.876 12.283 1.00 47.05 ? 24 ARG A NH2 1 ATOM 12 N N . LYS A 1 25 ? -1.002 23.414 7.226 1.00 30.84 ? 25 LYS A N 1 ATOM 13 C CA . LYS A 1 25 ? -0.949 22.696 5.954 1.00 29.18 ? 25 LYS A CA 1 ATOM 14 C C . LYS A 1 25 ? -0.266 21.340 6.120 1.00 26.69 ? 25 LYS A C 1 ATOM 15 O O . LYS A 1 25 ? 0.541 21.134 7.025 1.00 28.72 ? 25 LYS A O 1 ATOM 16 C CB . LYS A 1 25 ? -0.194 23.514 4.907 1.00 26.27 ? 25 LYS A CB 1 ATOM 17 C CG . LYS A 1 25 ? -0.746 24.917 4.640 1.00 35.80 ? 25 LYS A CG 1 ATOM 18 C CD . LYS A 1 25 ? -2.109 24.860 3.970 1.00 33.40 ? 25 LYS A CD 1 ATOM 19 C CE . LYS A 1 25 ? -2.410 26.143 3.182 1.00 36.59 ? 25 LYS A CE 1 ATOM 20 N NZ . LYS A 1 25 ? -2.177 27.364 4.007 1.00 50.97 ? 25 LYS A NZ 1 ATOM 21 N N . LEU A 1 26 ? -0.574 20.415 5.211 1.00 25.34 ? 26 LEU A N 1 ATOM 22 C CA . LEU A 1 26 ? -0.060 19.051 5.321 1.00 25.41 ? 26 LEU A CA 1 ATOM 23 C C . LEU A 1 26 ? 0.347 18.550 3.948 1.00 21.76 ? 26 LEU A C 1 ATOM 24 O O . LEU A 1 26 ? -0.424 18.671 2.995 1.00 21.43 ? 26 LEU A O 1 ATOM 25 C CB . LEU A 1 26 ? -1.104 18.105 5.928 1.00 22.77 ? 26 LEU A CB 1 ATOM 26 C CG . LEU A 1 26 ? -0.682 16.636 6.067 1.00 20.52 ? 26 LEU A CG 1 ATOM 27 C CD1 . LEU A 1 26 ? 0.646 16.495 6.829 1.00 21.82 ? 26 LEU A CD1 1 ATOM 28 C CD2 . LEU A 1 26 ? -1.786 15.804 6.749 1.00 25.63 ? 26 LEU A CD2 1 ATOM 29 N N . LEU A 1 27 ? 1.561 18.003 3.862 1.00 22.03 ? 27 LEU A N 1 ATOM 30 C CA . LEU A 1 27 ? 2.079 17.295 2.697 1.00 21.10 ? 27 LEU A CA 1 ATOM 31 C C . LEU A 1 27 ? 2.277 15.834 3.088 1.00 19.45 ? 27 LEU A C 1 ATOM 32 O O . LEU A 1 27 ? 3.003 15.557 4.040 1.00 18.62 ? 27 LEU A O 1 ATOM 33 C CB . LEU A 1 27 ? 3.411 17.903 2.243 1.00 19.04 ? 27 LEU A CB 1 ATOM 34 C CG . LEU A 1 27 ? 4.017 17.187 1.038 1.00 19.34 ? 27 LEU A CG 1 ATOM 35 C CD1 . LEU A 1 27 ? 3.076 17.290 -0.179 1.00 18.46 ? 27 LEU A CD1 1 ATOM 36 C CD2 . LEU A 1 27 ? 5.379 17.751 0.694 1.00 20.14 ? 27 LEU A CD2 1 ATOM 37 N N . VAL A 1 28 ? 1.619 14.911 2.376 1.00 15.72 ? 28 VAL A N 1 ATOM 38 C CA . VAL A 1 28 ? 1.734 13.475 2.629 1.00 19.74 ? 28 VAL A CA 1 ATOM 39 C C . VAL A 1 28 ? 2.439 12.826 1.444 1.00 18.11 ? 28 VAL A C 1 ATOM 40 O O . VAL A 1 28 ? 2.048 13.045 0.295 1.00 17.50 ? 28 VAL A O 1 ATOM 41 C CB . VAL A 1 28 ? 0.357 12.826 2.853 1.00 23.23 ? 28 VAL A CB 1 ATOM 42 C CG1 . VAL A 1 28 ? 0.502 11.308 3.041 1.00 21.88 ? 28 VAL A CG1 1 ATOM 43 C CG2 . VAL A 1 28 ? -0.336 13.464 4.042 1.00 24.38 ? 28 VAL A CG2 1 ATOM 44 N N . LEU A 1 29 ? 3.470 12.019 1.725 1.00 17.02 ? 29 LEU A N 1 ATOM 45 C CA . LEU A 1 29 ? 4.231 11.319 0.690 1.00 18.25 ? 29 LEU A CA 1 ATOM 46 C C . LEU A 1 29 ? 4.103 9.821 0.934 1.00 18.24 ? 29 LEU A C 1 ATOM 47 O O . LEU A 1 29 ? 4.512 9.340 1.987 1.00 17.89 ? 29 LEU A O 1 ATOM 48 C CB . LEU A 1 29 ? 5.715 11.715 0.722 1.00 19.08 ? 29 LEU A CB 1 ATOM 49 C CG . LEU A 1 29 ? 6.034 13.201 0.578 1.00 18.57 ? 29 LEU A CG 1 ATOM 50 C CD1 . LEU A 1 29 ? 7.558 13.408 0.529 1.00 22.39 ? 29 LEU A CD1 1 ATOM 51 C CD2 . LEU A 1 29 ? 5.353 13.768 -0.663 1.00 18.29 ? 29 LEU A CD2 1 ATOM 52 N N . LEU A 1 30 ? 3.552 9.099 -0.039 1.00 17.74 ? 30 LEU A N 1 ATOM 53 C CA . LEU A 1 30 ? 3.398 7.648 0.024 1.00 18.02 ? 30 LEU A CA 1 ATOM 54 C C . LEU A 1 30 ? 4.471 7.033 -0.869 1.00 17.81 ? 30 LEU A C 1 ATOM 55 O O . LEU A 1 30 ? 4.444 7.202 -2.093 1.00 18.16 ? 30 LEU A O 1 ATOM 56 C CB . LEU A 1 30 ? 1.983 7.244 -0.395 1.00 18.41 ? 30 LEU A CB 1 ATOM 57 C CG . LEU A 1 30 ? 1.646 5.784 -0.674 1.00 23.15 ? 30 LEU A CG 1 ATOM 58 C CD1 . LEU A 1 30 ? 2.174 4.901 0.412 1.00 20.61 ? 30 LEU A CD1 1 ATOM 59 C CD2 . LEU A 1 30 ? 0.138 5.591 -0.828 1.00 18.54 ? 30 LEU A CD2 1 ATOM 60 N N . LEU A 1 31 ? 5.437 6.337 -0.260 1.00 15.77 ? 31 LEU A N 1 ATOM 61 C CA . LEU A 1 31 ? 6.537 5.733 -1.014 1.00 18.24 ? 31 LEU A CA 1 ATOM 62 C C . LEU A 1 31 ? 6.295 4.224 -1.097 1.00 20.58 ? 31 LEU A C 1 ATOM 63 O O . LEU A 1 31 ? 6.584 3.477 -0.155 1.00 18.15 ? 31 LEU A O 1 ATOM 64 C CB . LEU A 1 31 ? 7.879 6.063 -0.365 1.00 17.22 ? 31 LEU A CB 1 ATOM 65 C CG . LEU A 1 31 ? 8.110 7.567 -0.146 1.00 24.03 ? 31 LEU A CG 1 ATOM 66 C CD1 . LEU A 1 31 ? 9.466 7.814 0.532 1.00 23.50 ? 31 LEU A CD1 1 ATOM 67 C CD2 . LEU A 1 31 ? 7.999 8.321 -1.469 1.00 20.95 ? 31 LEU A CD2 1 ATOM 68 N N . ASP A 1 32 ? 5.781 3.778 -2.235 1.00 17.54 ? 32 ASP A N 1 ATOM 69 C CA . ASP A 1 32 ? 5.346 2.393 -2.370 1.00 18.49 ? 32 ASP A CA 1 ATOM 70 C C . ASP A 1 32 ? 6.502 1.425 -2.159 1.00 15.98 ? 32 ASP A C 1 ATOM 71 O O . ASP A 1 32 ? 7.580 1.590 -2.733 1.00 19.65 ? 32 ASP A O 1 ATOM 72 C CB . ASP A 1 32 ? 4.743 2.172 -3.753 1.00 17.29 ? 32 ASP A CB 1 ATOM 73 C CG . ASP A 1 32 ? 3.808 0.997 -3.785 1.00 19.13 ? 32 ASP A CG 1 ATOM 74 O OD1 . ASP A 1 32 ? 4.215 -0.073 -3.319 1.00 19.46 ? 32 ASP A OD1 1 ATOM 75 O OD2 . ASP A 1 32 ? 2.655 1.150 -4.255 1.00 25.86 ? 32 ASP A OD2 1 ATOM 76 N N . GLY A 1 33 ? 6.267 0.396 -1.345 1.00 17.37 ? 33 GLY A N 1 ATOM 77 C CA . GLY A 1 33 ? 7.253 -0.667 -1.248 1.00 16.95 ? 33 GLY A CA 1 ATOM 78 C C . GLY A 1 33 ? 8.507 -0.342 -0.459 1.00 24.74 ? 33 GLY A C 1 ATOM 79 O O . GLY A 1 33 ? 9.512 -1.044 -0.602 1.00 20.65 ? 33 GLY A O 1 ATOM 80 N N . PHE A 1 34 ? 8.476 0.690 0.386 1.00 19.40 ? 34 PHE A N 1 ATOM 81 C CA . PHE A 1 34 ? 9.648 1.147 1.130 1.00 19.77 ? 34 PHE A CA 1 ATOM 82 C C . PHE A 1 34 ? 9.744 0.331 2.415 1.00 18.24 ? 34 PHE A C 1 ATOM 83 O O . PHE A 1 34 ? 9.031 0.598 3.392 1.00 17.39 ? 34 PHE A O 1 ATOM 84 C CB . PHE A 1 34 ? 9.508 2.641 1.410 1.00 18.71 ? 34 PHE A CB 1 ATOM 85 C CG . PHE A 1 34 ? 10.805 3.361 1.745 1.00 21.09 ? 34 PHE A CG 1 ATOM 86 C CD1 . PHE A 1 34 ? 11.604 2.958 2.806 1.00 21.20 ? 34 PHE A CD1 1 ATOM 87 C CD2 . PHE A 1 34 ? 11.156 4.508 1.048 1.00 21.08 ? 34 PHE A CD2 1 ATOM 88 C CE1 . PHE A 1 34 ? 12.769 3.661 3.142 1.00 22.60 ? 34 PHE A CE1 1 ATOM 89 C CE2 . PHE A 1 34 ? 12.320 5.215 1.368 1.00 23.47 ? 34 PHE A CE2 1 ATOM 90 C CZ . PHE A 1 34 ? 13.126 4.791 2.424 1.00 23.41 ? 34 PHE A CZ 1 ATOM 91 N N . ARG A 1 35 ? 10.634 -0.659 2.416 1.00 18.48 ? 35 ARG A N 1 ATOM 92 C CA . ARG A 1 35 ? 10.817 -1.543 3.564 1.00 18.68 ? 35 ARG A CA 1 ATOM 93 C C . ARG A 1 35 ? 11.529 -0.817 4.706 1.00 19.07 ? 35 ARG A C 1 ATOM 94 O O . ARG A 1 35 ? 12.405 0.017 4.483 1.00 21.71 ? 35 ARG A O 1 ATOM 95 C CB . ARG A 1 35 ? 11.633 -2.773 3.149 1.00 21.46 ? 35 ARG A CB 1 ATOM 96 C CG . ARG A 1 35 ? 11.671 -3.885 4.170 1.00 21.79 ? 35 ARG A CG 1 ATOM 97 C CD . ARG A 1 35 ? 12.267 -5.151 3.569 1.00 27.05 ? 35 ARG A CD 1 ATOM 98 N NE . ARG A 1 35 ? 13.726 -5.123 3.540 1.00 28.18 ? 35 ARG A NE 1 ATOM 99 C CZ . ARG A 1 35 ? 14.480 -6.103 3.045 1.00 30.54 ? 35 ARG A CZ 1 ATOM 100 N NH1 . ARG A 1 35 ? 13.912 -7.179 2.521 1.00 23.78 ? 35 ARG A NH1 1 ATOM 101 N NH2 . ARG A 1 35 ? 15.806 -6.008 3.069 1.00 38.07 ? 35 ARG A NH2 1 ATOM 102 N N A SER A 1 36 ? 11.157 -1.177 5.939 0.50 18.88 ? 36 SER A N 1 ATOM 103 N N B SER A 1 36 ? 11.169 -1.182 5.943 0.50 18.89 ? 36 SER A N 1 ATOM 104 C CA A SER A 1 36 ? 11.618 -0.448 7.119 0.50 21.08 ? 36 SER A CA 1 ATOM 105 C CA B SER A 1 36 ? 11.621 -0.430 7.113 0.50 21.07 ? 36 SER A CA 1 ATOM 106 C C A SER A 1 36 ? 13.140 -0.378 7.191 0.50 22.18 ? 36 SER A C 1 ATOM 107 C C B SER A 1 36 ? 13.142 -0.381 7.213 0.50 22.18 ? 36 SER A C 1 ATOM 108 O O A SER A 1 36 ? 13.711 0.676 7.494 0.50 20.94 ? 36 SER A O 1 ATOM 109 O O B SER A 1 36 ? 13.714 0.661 7.552 0.50 20.93 ? 36 SER A O 1 ATOM 110 C CB A SER A 1 36 ? 11.059 -1.101 8.381 0.50 23.88 ? 36 SER A CB 1 ATOM 111 C CB B SER A 1 36 ? 11.027 -1.028 8.389 0.50 23.87 ? 36 SER A CB 1 ATOM 112 O OG A SER A 1 36 ? 11.814 -0.731 9.517 0.50 21.33 ? 36 SER A OG 1 ATOM 113 O OG B SER A 1 36 ? 11.530 -2.331 8.644 0.50 20.89 ? 36 SER A OG 1 ATOM 114 N N . ASP A 1 37 ? 13.818 -1.493 6.931 1.00 22.86 ? 37 ASP A N 1 ATOM 115 C CA . ASP A 1 37 ? 15.268 -1.495 7.080 1.00 24.39 ? 37 ASP A CA 1 ATOM 116 C C . ASP A 1 37 ? 15.998 -0.858 5.899 1.00 27.14 ? 37 ASP A C 1 ATOM 117 O O . ASP A 1 37 ? 17.229 -0.818 5.905 1.00 27.01 ? 37 ASP A O 1 ATOM 118 C CB . ASP A 1 37 ? 15.789 -2.918 7.370 1.00 24.88 ? 37 ASP A CB 1 ATOM 119 C CG . ASP A 1 37 ? 15.702 -3.861 6.189 1.00 27.67 ? 37 ASP A CG 1 ATOM 120 O OD1 . ASP A 1 37 ? 15.330 -3.466 5.070 1.00 27.66 ? 37 ASP A OD1 1 ATOM 121 O OD2 . ASP A 1 37 ? 16.050 -5.045 6.395 1.00 32.03 ? 37 ASP A OD2 1 ATOM 122 N N . TYR A 1 38 ? 15.283 -0.310 4.909 1.00 21.97 ? 38 TYR A N 1 ATOM 123 C CA . TYR A 1 38 ? 15.941 0.516 3.902 1.00 21.90 ? 38 TYR A CA 1 ATOM 124 C C . TYR A 1 38 ? 16.537 1.788 4.499 1.00 22.12 ? 38 TYR A C 1 ATOM 125 O O . TYR A 1 38 ? 17.378 2.430 3.857 1.00 23.02 ? 38 TYR A O 1 ATOM 126 C CB . TYR A 1 38 ? 14.960 0.920 2.798 1.00 22.26 ? 38 TYR A CB 1 ATOM 127 C CG . TYR A 1 38 ? 14.505 -0.170 1.845 1.00 22.05 ? 38 TYR A CG 1 ATOM 128 C CD1 . TYR A 1 38 ? 15.077 -1.450 1.846 1.00 24.74 ? 38 TYR A CD1 1 ATOM 129 C CD2 . TYR A 1 38 ? 13.497 0.098 0.928 1.00 20.72 ? 38 TYR A CD2 1 ATOM 130 C CE1 . TYR A 1 38 ? 14.637 -2.433 0.938 1.00 21.17 ? 38 TYR A CE1 1 ATOM 131 C CE2 . TYR A 1 38 ? 13.044 -0.866 0.042 1.00 20.64 ? 38 TYR A CE2 1 ATOM 132 C CZ . TYR A 1 38 ? 13.614 -2.122 0.042 1.00 21.54 ? 38 TYR A CZ 1 ATOM 133 O OH . TYR A 1 38 ? 13.142 -3.039 -0.871 1.00 21.87 ? 38 TYR A OH 1 ATOM 134 N N . ILE A 1 39 ? 16.072 2.202 5.675 1.00 22.39 ? 39 ILE A N 1 ATOM 135 C CA . ILE A 1 39 ? 16.650 3.342 6.377 1.00 23.28 ? 39 ILE A CA 1 ATOM 136 C C . ILE A 1 39 ? 17.103 2.902 7.762 1.00 24.11 ? 39 ILE A C 1 ATOM 137 O O . ILE A 1 39 ? 16.910 3.612 8.757 1.00 23.26 ? 39 ILE A O 1 ATOM 138 C CB . ILE A 1 39 ? 15.661 4.518 6.455 1.00 23.70 ? 39 ILE A CB 1 ATOM 139 C CG1 . ILE A 1 39 ? 14.292 4.037 6.936 1.00 22.54 ? 39 ILE A CG1 1 ATOM 140 C CG2 . ILE A 1 39 ? 15.579 5.220 5.097 1.00 23.64 ? 39 ILE A CG2 1 ATOM 141 C CD1 . ILE A 1 39 ? 13.329 5.189 7.204 1.00 23.78 ? 39 ILE A CD1 1 ATOM 142 N N . SER A 1 40 ? 17.710 1.723 7.835 1.00 27.13 ? 40 SER A N 1 ATOM 143 C CA . SER A 1 40 ? 18.402 1.333 9.051 1.00 30.39 ? 40 SER A CA 1 ATOM 144 C C . SER A 1 40 ? 19.496 2.346 9.393 1.00 29.72 ? 40 SER A C 1 ATOM 145 O O . SER A 1 40 ? 19.859 3.206 8.593 1.00 29.89 ? 40 SER A O 1 ATOM 146 C CB . SER A 1 40 ? 19.028 -0.042 8.876 1.00 29.61 ? 40 SER A CB 1 ATOM 147 O OG . SER A 1 40 ? 20.041 0.050 7.894 1.00 29.51 ? 40 SER A OG 1 ATOM 148 N N . GLU A 1 41 ? 20.036 2.226 10.606 1.00 33.82 ? 41 GLU A N 1 ATOM 149 C CA . GLU A 1 41 ? 21.138 3.097 11.008 1.00 32.52 ? 41 GLU A CA 1 ATOM 150 C C . GLU A 1 41 ? 22.279 3.045 9.992 1.00 30.68 ? 41 GLU A C 1 ATOM 151 O O . GLU A 1 41 ? 22.784 4.086 9.549 1.00 31.99 ? 41 GLU A O 1 ATOM 152 C CB . GLU A 1 41 ? 21.628 2.705 12.403 1.00 38.52 ? 41 GLU A CB 1 ATOM 153 C CG . GLU A 1 41 ? 22.638 3.673 13.006 1.00 49.67 ? 41 GLU A CG 1 ATOM 154 C CD . GLU A 1 41 ? 21.982 4.908 13.602 1.00 59.94 ? 41 GLU A CD 1 ATOM 155 O OE1 . GLU A 1 41 ? 20.787 4.833 13.963 1.00 57.82 ? 41 GLU A OE1 1 ATOM 156 O OE2 . GLU A 1 41 ? 22.662 5.952 13.711 1.00 63.59 ? 41 GLU A OE2 1 ATOM 157 N N . ASP A 1 42 ? 22.674 1.836 9.581 1.00 35.21 ? 42 ASP A N 1 ATOM 158 C CA . ASP A 1 42 ? 23.775 1.713 8.627 1.00 34.47 ? 42 ASP A CA 1 ATOM 159 C C . ASP A 1 42 ? 23.425 2.373 7.301 1.00 36.10 ? 42 ASP A C 1 ATOM 160 O O . ASP A 1 42 ? 24.267 3.041 6.693 1.00 31.86 ? 42 ASP A O 1 ATOM 161 C CB . ASP A 1 42 ? 24.141 0.245 8.404 1.00 37.56 ? 42 ASP A CB 1 ATOM 162 C CG . ASP A 1 42 ? 24.536 -0.474 9.694 1.00 48.01 ? 42 ASP A CG 1 ATOM 163 O OD1 . ASP A 1 42 ? 24.989 0.195 10.650 1.00 41.80 ? 42 ASP A OD1 1 ATOM 164 O OD2 . ASP A 1 42 ? 24.392 -1.720 9.746 1.00 44.09 ? 42 ASP A OD2 1 ATOM 165 N N . ALA A 1 43 ? 22.179 2.210 6.844 1.00 31.56 ? 43 ALA A N 1 ATOM 166 C CA . ALA A 1 43 ? 21.791 2.780 5.557 1.00 32.57 ? 43 ALA A CA 1 ATOM 167 C C . ALA A 1 43 ? 21.765 4.304 5.605 1.00 28.63 ? 43 ALA A C 1 ATOM 168 O O . ALA A 1 43 ? 22.158 4.968 4.638 1.00 30.70 ? 43 ALA A O 1 ATOM 169 C CB . ALA A 1 43 ? 20.429 2.229 5.125 1.00 27.56 ? 43 ALA A CB 1 ATOM 170 N N . LEU A 1 44 ? 21.320 4.877 6.728 1.00 28.03 ? 44 LEU A N 1 ATOM 171 C CA . LEU A 1 44 ? 21.176 6.324 6.829 1.00 31.82 ? 44 LEU A CA 1 ATOM 172 C C . LEU A 1 44 ? 22.505 7.059 6.709 1.00 36.07 ? 44 LEU A C 1 ATOM 173 O O . LEU A 1 44 ? 22.513 8.252 6.384 1.00 34.45 ? 44 LEU A O 1 ATOM 174 C CB . LEU A 1 44 ? 20.496 6.694 8.148 1.00 30.91 ? 44 LEU A CB 1 ATOM 175 C CG . LEU A 1 44 ? 18.980 6.505 8.201 1.00 27.45 ? 44 LEU A CG 1 ATOM 176 C CD1 . LEU A 1 44 ? 18.479 6.704 9.623 1.00 28.45 ? 44 LEU A CD1 1 ATOM 177 C CD2 . LEU A 1 44 ? 18.268 7.455 7.222 1.00 25.85 ? 44 LEU A CD2 1 ATOM 178 N N . ALA A 1 45 ? 23.626 6.378 6.947 1.00 38.84 ? 45 ALA A N 1 ATOM 179 C CA . ALA A 1 45 ? 24.927 7.018 6.794 1.00 40.58 ? 45 ALA A CA 1 ATOM 180 C C . ALA A 1 45 ? 25.188 7.478 5.365 1.00 39.26 ? 45 ALA A C 1 ATOM 181 O O . ALA A 1 45 ? 26.021 8.367 5.158 1.00 42.15 ? 45 ALA A O 1 ATOM 182 C CB . ALA A 1 45 ? 26.033 6.068 7.257 1.00 39.08 ? 45 ALA A CB 1 ATOM 183 N N . SER A 1 46 ? 24.491 6.919 4.375 1.00 37.87 ? 46 SER A N 1 ATOM 184 C CA . SER A 1 46 ? 24.639 7.371 2.996 1.00 38.31 ? 46 SER A CA 1 ATOM 185 C C . SER A 1 46 ? 23.351 7.952 2.424 1.00 35.32 ? 46 SER A C 1 ATOM 186 O O . SER A 1 46 ? 23.205 8.024 1.203 1.00 39.08 ? 46 SER A O 1 ATOM 187 C CB . SER A 1 46 ? 25.140 6.233 2.106 1.00 45.67 ? 46 SER A CB 1 ATOM 188 O OG . SER A 1 46 ? 24.235 5.147 2.092 1.00 51.38 ? 46 SER A OG 1 ATOM 189 N N . LEU A 1 47 ? 22.417 8.375 3.272 1.00 33.25 ? 47 LEU A N 1 ATOM 190 C CA . LEU A 1 47 ? 21.124 8.902 2.826 1.00 33.81 ? 47 LEU A CA 1 ATOM 191 C C . LEU A 1 47 ? 20.909 10.267 3.469 1.00 28.96 ? 47 LEU A C 1 ATOM 192 O O . LEU A 1 47 ? 20.202 10.392 4.480 1.00 32.41 ? 47 LEU A O 1 ATOM 193 C CB . LEU A 1 47 ? 19.994 7.923 3.154 1.00 29.64 ? 47 LEU A CB 1 ATOM 194 C CG . LEU A 1 47 ? 20.062 6.593 2.392 1.00 32.68 ? 47 LEU A CG 1 ATOM 195 C CD1 . LEU A 1 47 ? 19.032 5.599 2.927 1.00 31.52 ? 47 LEU A CD1 1 ATOM 196 C CD2 . LEU A 1 47 ? 19.873 6.798 0.894 1.00 34.72 ? 47 LEU A CD2 1 ATOM 197 N N . PRO A 1 48 ? 21.505 11.320 2.899 1.00 31.21 ? 48 PRO A N 1 ATOM 198 C CA . PRO A 1 48 ? 21.450 12.636 3.562 1.00 27.39 ? 48 PRO A CA 1 ATOM 199 C C . PRO A 1 48 ? 20.048 13.201 3.691 1.00 27.72 ? 48 PRO A C 1 ATOM 200 O O . PRO A 1 48 ? 19.750 13.865 4.689 1.00 31.98 ? 48 PRO A O 1 ATOM 201 C CB . PRO A 1 48 ? 22.345 13.511 2.671 1.00 33.85 ? 48 PRO A CB 1 ATOM 202 C CG . PRO A 1 48 ? 22.373 12.808 1.336 1.00 36.71 ? 48 PRO A CG 1 ATOM 203 C CD . PRO A 1 48 ? 22.315 11.346 1.669 1.00 33.20 ? 48 PRO A CD 1 ATOM 204 N N . GLY A 1 49 ? 19.173 12.962 2.712 1.00 27.48 ? 49 GLY A N 1 ATOM 205 C CA . GLY A 1 49 ? 17.821 13.493 2.807 1.00 25.88 ? 49 GLY A CA 1 ATOM 206 C C . GLY A 1 49 ? 17.040 12.883 3.958 1.00 24.04 ? 49 GLY A C 1 ATOM 207 O O . GLY A 1 49 ? 16.474 13.594 4.793 1.00 26.63 ? 49 GLY A O 1 ATOM 208 N N . PHE A 1 50 ? 16.982 11.548 4.009 1.00 27.42 ? 50 PHE A N 1 ATOM 209 C CA . PHE A 1 50 ? 16.317 10.893 5.133 1.00 26.55 ? 50 PHE A CA 1 ATOM 210 C C . PHE A 1 50 ? 17.034 11.172 6.448 1.00 22.36 ? 50 PHE A C 1 ATOM 211 O O . PHE A 1 50 ? 16.388 11.333 7.489 1.00 25.51 ? 50 PHE A O 1 ATOM 212 C CB . PHE A 1 50 ? 16.211 9.388 4.893 1.00 26.17 ? 50 PHE A CB 1 ATOM 213 C CG . PHE A 1 50 ? 15.120 9.013 3.933 1.00 22.73 ? 50 PHE A CG 1 ATOM 214 C CD1 . PHE A 1 50 ? 13.803 8.964 4.347 1.00 28.85 ? 50 PHE A CD1 1 ATOM 215 C CD2 . PHE A 1 50 ? 15.414 8.726 2.620 1.00 23.29 ? 50 PHE A CD2 1 ATOM 216 C CE1 . PHE A 1 50 ? 12.794 8.640 3.456 1.00 25.93 ? 50 PHE A CE1 1 ATOM 217 C CE2 . PHE A 1 50 ? 14.414 8.396 1.731 1.00 29.55 ? 50 PHE A CE2 1 ATOM 218 C CZ . PHE A 1 50 ? 13.099 8.350 2.158 1.00 24.10 ? 50 PHE A CZ 1 ATOM 219 N N . ARG A 1 51 ? 18.367 11.226 6.431 1.00 29.28 ? 51 ARG A N 1 ATOM 220 C CA . ARG A 1 51 ? 19.077 11.504 7.675 1.00 29.98 ? 51 ARG A CA 1 ATOM 221 C C . ARG A 1 51 ? 18.660 12.853 8.242 1.00 27.76 ? 51 ARG A C 1 ATOM 222 O O . ARG A 1 51 ? 18.525 13.006 9.463 1.00 31.35 ? 51 ARG A O 1 ATOM 223 C CB . ARG A 1 51 ? 20.593 11.447 7.461 1.00 29.97 ? 51 ARG A CB 1 ATOM 224 C CG . ARG A 1 51 ? 21.379 11.392 8.767 1.00 35.45 ? 51 ARG A CG 1 ATOM 225 C CD . ARG A 1 51 ? 22.856 11.075 8.542 1.00 30.62 ? 51 ARG A CD 1 ATOM 226 N NE . ARG A 1 51 ? 23.488 12.050 7.657 1.00 37.43 ? 51 ARG A NE 1 ATOM 227 C CZ . ARG A 1 51 ? 23.995 11.762 6.462 1.00 34.43 ? 51 ARG A CZ 1 ATOM 228 N NH1 . ARG A 1 51 ? 23.965 10.516 5.998 1.00 33.81 ? 51 ARG A NH1 1 ATOM 229 N NH2 . ARG A 1 51 ? 24.546 12.721 5.734 1.00 40.18 ? 51 ARG A NH2 1 ATOM 230 N N . GLU A 1 52 ? 18.428 13.843 7.373 1.00 30.22 ? 52 GLU A N 1 ATOM 231 C CA . GLU A 1 52 ? 18.010 15.146 7.873 1.00 30.21 ? 52 GLU A CA 1 ATOM 232 C C . GLU A 1 52 ? 16.601 15.083 8.446 1.00 32.39 ? 52 GLU A C 1 ATOM 233 O O . GLU A 1 52 ? 16.331 15.663 9.504 1.00 27.99 ? 52 GLU A O 1 ATOM 234 C CB . GLU A 1 52 ? 18.090 16.211 6.778 1.00 30.67 ? 52 GLU A CB 1 ATOM 235 C CG . GLU A 1 52 ? 17.739 17.585 7.323 1.00 37.59 ? 52 GLU A CG 1 ATOM 236 C CD . GLU A 1 52 ? 17.952 18.730 6.344 1.00 42.64 ? 52 GLU A CD 1 ATOM 237 O OE1 . GLU A 1 52 ? 18.346 18.482 5.183 1.00 40.57 ? 52 GLU A OE1 1 ATOM 238 O OE2 . GLU A 1 52 ? 17.717 19.893 6.750 1.00 40.54 ? 52 GLU A OE2 1 ATOM 239 N N . ILE A 1 53 ? 15.693 14.367 7.771 1.00 25.39 ? 53 ILE A N 1 ATOM 240 C CA . ILE A 1 53 ? 14.350 14.189 8.309 1.00 27.26 ? 53 ILE A CA 1 ATOM 241 C C . ILE A 1 53 ? 14.407 13.510 9.667 1.00 26.74 ? 53 ILE A C 1 ATOM 242 O O . ILE A 1 53 ? 13.728 13.927 10.616 1.00 27.19 ? 53 ILE A O 1 ATOM 243 C CB . ILE A 1 53 ? 13.473 13.410 7.306 1.00 23.54 ? 53 ILE A CB 1 ATOM 244 C CG1 . ILE A 1 53 ? 13.344 14.213 6.014 1.00 24.91 ? 53 ILE A CG1 1 ATOM 245 C CG2 . ILE A 1 53 ? 12.108 13.123 7.907 1.00 27.36 ? 53 ILE A CG2 1 ATOM 246 C CD1 . ILE A 1 53 ? 12.604 13.490 4.882 1.00 27.60 ? 53 ILE A CD1 1 ATOM 247 N N . VAL A 1 54 ? 15.237 12.469 9.787 1.00 27.48 ? 54 VAL A N 1 ATOM 248 C CA . VAL A 1 54 ? 15.403 11.767 11.059 1.00 28.02 ? 54 VAL A CA 1 ATOM 249 C C . VAL A 1 54 ? 15.974 12.710 12.116 1.00 31.77 ? 54 VAL A C 1 ATOM 250 O O . VAL A 1 54 ? 15.544 12.713 13.275 1.00 30.47 ? 54 VAL A O 1 ATOM 251 C CB . VAL A 1 54 ? 16.301 10.530 10.862 1.00 29.19 ? 54 VAL A CB 1 ATOM 252 C CG1 . VAL A 1 54 ? 16.793 9.971 12.199 1.00 33.35 ? 54 VAL A CG1 1 ATOM 253 C CG2 . VAL A 1 54 ? 15.571 9.453 10.064 1.00 27.21 ? 54 VAL A CG2 1 ATOM 254 N N . ASN A 1 55 ? 16.958 13.525 11.729 1.00 32.33 ? 55 ASN A N 1 ATOM 255 C CA . ASN A 1 55 ? 17.640 14.362 12.713 1.00 31.61 ? 55 ASN A CA 1 ATOM 256 C C . ASN A 1 55 ? 16.758 15.494 13.202 1.00 33.76 ? 55 ASN A C 1 ATOM 257 O O . ASN A 1 55 ? 16.936 15.974 14.328 1.00 33.66 ? 55 ASN A O 1 ATOM 258 C CB . ASN A 1 55 ? 18.921 14.925 12.123 1.00 33.63 ? 55 ASN A CB 1 ATOM 259 C CG . ASN A 1 55 ? 20.000 13.892 12.030 1.00 37.65 ? 55 ASN A CG 1 ATOM 260 O OD1 . ASN A 1 55 ? 19.987 12.911 12.769 1.00 37.38 ? 55 ASN A OD1 1 ATOM 261 N ND2 . ASN A 1 55 ? 20.944 14.097 11.124 1.00 40.37 ? 55 ASN A ND2 1 ATOM 262 N N . ARG A 1 56 ? 15.799 15.922 12.383 1.00 31.92 ? 56 ARG A N 1 ATOM 263 C CA . ARG A 1 56 ? 14.976 17.084 12.681 1.00 31.97 ? 56 ARG A CA 1 ATOM 264 C C . ARG A 1 56 ? 13.503 16.739 12.893 1.00 30.61 ? 56 ARG A C 1 ATOM 265 O O . ARG A 1 56 ? 12.690 17.646 13.098 1.00 31.08 ? 56 ARG A O 1 ATOM 266 C CB . ARG A 1 56 ? 15.136 18.118 11.560 1.00 27.10 ? 56 ARG A CB 1 ATOM 267 C CG . ARG A 1 56 ? 16.590 18.595 11.384 1.00 35.86 ? 56 ARG A CG 1 ATOM 268 C CD . ARG A 1 56 ? 16.738 19.544 10.200 1.00 37.67 ? 56 ARG A CD 1 ATOM 269 N NE . ARG A 1 56 ? 15.743 20.599 10.230 1.00 45.92 ? 56 ARG A NE 1 ATOM 270 C CZ . ARG A 1 56 ? 15.374 21.306 9.169 1.00 51.20 ? 56 ARG A CZ 1 ATOM 271 N NH1 . ARG A 1 56 ? 15.918 21.060 7.984 1.00 50.08 ? 56 ARG A NH1 1 ATOM 272 N NH2 . ARG A 1 56 ? 14.454 22.254 9.292 1.00 58.22 ? 56 ARG A NH2 1 ATOM 273 N N . GLY A 1 57 ? 13.137 15.467 12.863 1.00 30.87 ? 57 GLY A N 1 ATOM 274 C CA . GLY A 1 57 ? 11.746 15.064 12.991 1.00 26.93 ? 57 GLY A CA 1 ATOM 275 C C . GLY A 1 57 ? 11.585 13.731 13.692 1.00 30.53 ? 57 GLY A C 1 ATOM 276 O O . GLY A 1 57 ? 12.391 13.357 14.550 1.00 29.23 ? 57 GLY A O 1 ATOM 277 N N . VAL A 1 58 ? 10.527 13.010 13.308 1.00 27.24 ? 58 VAL A N 1 ATOM 278 C CA . VAL A 1 58 ? 10.097 11.766 13.940 1.00 21.94 ? 58 VAL A CA 1 ATOM 279 C C . VAL A 1 58 ? 10.365 10.611 12.985 1.00 25.21 ? 58 VAL A C 1 ATOM 280 O O . VAL A 1 58 ? 10.082 10.713 11.785 1.00 21.32 ? 58 VAL A O 1 ATOM 281 C CB . VAL A 1 58 ? 8.593 11.827 14.292 1.00 29.06 ? 58 VAL A CB 1 ATOM 282 C CG1 . VAL A 1 58 ? 8.053 10.449 14.668 1.00 25.03 ? 58 VAL A CG1 1 ATOM 283 C CG2 . VAL A 1 58 ? 8.325 12.847 15.405 1.00 32.60 ? 58 VAL A CG2 1 ATOM 284 N N . LYS A 1 59 ? 10.908 9.508 13.508 1.00 26.37 ? 59 LYS A N 1 ATOM 285 C CA . LYS A 1 59 ? 10.965 8.254 12.756 1.00 28.97 ? 59 LYS A CA 1 ATOM 286 C C . LYS A 1 59 ? 10.503 7.109 13.648 1.00 28.60 ? 59 LYS A C 1 ATOM 287 O O . LYS A 1 59 ? 11.086 6.876 14.713 1.00 27.73 ? 59 LYS A O 1 ATOM 288 C CB . LYS A 1 59 ? 12.375 7.965 12.231 1.00 29.71 ? 59 LYS A CB 1 ATOM 289 C CG . LYS A 1 59 ? 12.480 6.607 11.545 1.00 25.92 ? 59 LYS A CG 1 ATOM 290 C CD . LYS A 1 59 ? 13.909 6.186 11.262 1.00 26.49 ? 59 LYS A CD 1 ATOM 291 C CE . LYS A 1 59 ? 13.950 4.798 10.639 1.00 32.65 ? 59 LYS A CE 1 ATOM 292 N NZ . LYS A 1 59 ? 13.518 3.708 11.581 1.00 31.70 ? 59 LYS A NZ 1 ATOM 293 N N . VAL A 1 60 ? 9.482 6.366 13.209 1.00 25.22 ? 60 VAL A N 1 ATOM 294 C CA . VAL A 1 60 ? 9.119 5.150 13.933 1.00 21.48 ? 60 VAL A CA 1 ATOM 295 C C . VAL A 1 60 ? 10.112 4.054 13.588 1.00 22.23 ? 60 VAL A C 1 ATOM 296 O O . VAL A 1 60 ? 10.711 4.048 12.505 1.00 21.51 ? 60 VAL A O 1 ATOM 297 C CB . VAL A 1 60 ? 7.678 4.703 13.627 1.00 27.92 ? 60 VAL A CB 1 ATOM 298 C CG1 . VAL A 1 60 ? 6.686 5.821 13.942 1.00 27.42 ? 60 VAL A CG1 1 ATOM 299 C CG2 . VAL A 1 60 ? 7.566 4.220 12.184 1.00 25.86 ? 60 VAL A CG2 1 ATOM 300 N N . ASP A 1 61 ? 10.296 3.111 14.524 1.00 24.38 ? 61 ASP A N 1 ATOM 301 C CA . ASP A 1 61 ? 11.202 2.000 14.259 1.00 29.15 ? 61 ASP A CA 1 ATOM 302 C C . ASP A 1 61 ? 10.752 1.224 13.032 1.00 24.85 ? 61 ASP A C 1 ATOM 303 O O . ASP A 1 61 ? 11.577 0.841 12.200 1.00 22.15 ? 61 ASP A O 1 ATOM 304 C CB . ASP A 1 61 ? 11.303 1.079 15.480 1.00 25.05 ? 61 ASP A CB 1 ATOM 305 C CG . ASP A 1 61 ? 12.137 1.687 16.598 1.00 29.76 ? 61 ASP A CG 1 ATOM 306 O OD1 . ASP A 1 61 ? 12.522 2.873 16.485 1.00 32.98 ? 61 ASP A OD1 1 ATOM 307 O OD2 . ASP A 1 61 ? 12.402 0.981 17.594 1.00 35.65 ? 61 ASP A OD2 1 ATOM 308 N N . TYR A 1 62 ? 9.442 1.026 12.885 1.00 23.01 ? 62 TYR A N 1 ATOM 309 C CA . TYR A 1 62 ? 8.870 0.452 11.675 1.00 24.18 ? 62 TYR A CA 1 ATOM 310 C C . TYR A 1 62 ? 7.360 0.630 11.722 1.00 21.12 ? 62 TYR A C 1 ATOM 311 O O . TYR A 1 62 ? 6.778 0.892 12.777 1.00 20.63 ? 62 TYR A O 1 ATOM 312 C CB . TYR A 1 62 ? 9.226 -1.036 11.486 1.00 21.92 ? 62 TYR A CB 1 ATOM 313 C CG . TYR A 1 62 ? 8.956 -1.959 12.664 1.00 22.92 ? 62 TYR A CG 1 ATOM 314 C CD1 . TYR A 1 62 ? 7.725 -2.611 12.816 1.00 23.15 ? 62 TYR A CD1 1 ATOM 315 C CD2 . TYR A 1 62 ? 9.948 -2.214 13.597 1.00 26.75 ? 62 TYR A CD2 1 ATOM 316 C CE1 . TYR A 1 62 ? 7.499 -3.485 13.919 1.00 22.82 ? 62 TYR A CE1 1 ATOM 317 C CE2 . TYR A 1 62 ? 9.731 -3.063 14.676 1.00 29.81 ? 62 TYR A CE2 1 ATOM 318 C CZ . TYR A 1 62 ? 8.517 -3.692 14.832 1.00 24.74 ? 62 TYR A CZ 1 ATOM 319 O OH . TYR A 1 62 ? 8.327 -4.532 15.925 1.00 23.49 ? 62 TYR A OH 1 ATOM 320 N N . LEU A 1 63 ? 6.746 0.465 10.558 1.00 16.98 ? 63 LEU A N 1 ATOM 321 C CA . LEU A 1 63 ? 5.301 0.498 10.369 1.00 20.06 ? 63 LEU A CA 1 ATOM 322 C C . LEU A 1 63 ? 4.843 -0.902 9.968 1.00 18.38 ? 63 LEU A C 1 ATOM 323 O O . LEU A 1 63 ? 5.310 -1.443 8.959 1.00 22.86 ? 63 LEU A O 1 ATOM 324 C CB . LEU A 1 63 ? 4.924 1.525 9.290 1.00 18.36 ? 63 LEU A CB 1 ATOM 325 C CG . LEU A 1 63 ? 3.433 1.675 8.954 1.00 21.17 ? 63 LEU A CG 1 ATOM 326 C CD1 . LEU A 1 63 ? 2.665 2.056 10.173 1.00 27.87 ? 63 LEU A CD1 1 ATOM 327 C CD2 . LEU A 1 63 ? 3.214 2.747 7.904 1.00 21.68 ? 63 LEU A CD2 1 ATOM 328 N N . THR A 1 64 ? 3.960 -1.499 10.764 1.00 18.39 ? 64 THR A N 1 ATOM 329 C CA . THR A 1 64 ? 3.421 -2.817 10.428 1.00 15.95 ? 64 THR A CA 1 ATOM 330 C C . THR A 1 64 ? 2.188 -2.647 9.553 1.00 19.70 ? 64 THR A C 1 ATOM 331 O O . THR A 1 64 ? 1.225 -2.006 9.987 1.00 19.07 ? 64 THR A O 1 ATOM 332 C CB . THR A 1 64 ? 3.061 -3.587 11.684 1.00 24.43 ? 64 THR A CB 1 ATOM 333 O OG1 . THR A 1 64 ? 4.246 -3.806 12.471 1.00 22.32 ? 64 THR A OG1 1 ATOM 334 C CG2 . THR A 1 64 ? 2.431 -4.941 11.321 1.00 21.51 ? 64 THR A CG2 1 ATOM 335 N N . PRO A 1 65 ? 2.156 -3.210 8.347 1.00 19.90 ? 65 PRO A N 1 ATOM 336 C CA . PRO A 1 65 ? 1.005 -3.014 7.460 1.00 19.58 ? 65 PRO A CA 1 ATOM 337 C C . PRO A 1 65 ? -0.159 -3.898 7.891 1.00 22.56 ? 65 PRO A C 1 ATOM 338 O O . PRO A 1 65 ? -0.026 -4.768 8.747 1.00 18.82 ? 65 PRO A O 1 ATOM 339 C CB . PRO A 1 65 ? 1.538 -3.441 6.085 1.00 16.36 ? 65 PRO A CB 1 ATOM 340 C CG . PRO A 1 65 ? 2.593 -4.498 6.427 1.00 18.65 ? 65 PRO A CG 1 ATOM 341 C CD . PRO A 1 65 ? 3.211 -4.042 7.734 1.00 18.52 ? 65 PRO A CD 1 ATOM 342 N N . ASP A 1 66 ? -1.319 -3.634 7.291 1.00 21.25 ? 66 ASP A N 1 ATOM 343 C CA . ASP A 1 66 ? -2.441 -4.559 7.354 1.00 19.77 ? 66 ASP A CA 1 ATOM 344 C C . ASP A 1 66 ? -2.172 -5.785 6.491 1.00 17.76 ? 66 ASP A C 1 ATOM 345 O O . ASP A 1 66 ? -1.376 -5.750 5.554 1.00 18.67 ? 66 ASP A O 1 ATOM 346 C CB . ASP A 1 66 ? -3.723 -3.905 6.832 1.00 19.87 ? 66 ASP A CB 1 ATOM 347 C CG . ASP A 1 66 ? -4.683 -3.536 7.937 1.00 27.23 ? 66 ASP A CG 1 ATOM 348 O OD1 . ASP A 1 66 ? -4.406 -3.865 9.115 1.00 28.47 ? 66 ASP A OD1 1 ATOM 349 O OD2 . ASP A 1 66 ? -5.720 -2.914 7.618 1.00 27.12 ? 66 ASP A OD2 1 ATOM 350 N N . PHE A 1 67 ? -2.851 -6.878 6.825 1.00 16.70 ? 67 PHE A N 1 ATOM 351 C CA . PHE A 1 67 ? -2.943 -8.026 5.927 1.00 19.23 ? 67 PHE A CA 1 ATOM 352 C C . PHE A 1 67 ? -4.121 -7.806 4.975 1.00 16.91 ? 67 PHE A C 1 ATOM 353 O O . PHE A 1 67 ? -5.179 -7.355 5.414 1.00 19.43 ? 67 PHE A O 1 ATOM 354 C CB . PHE A 1 67 ? -3.119 -9.350 6.710 1.00 20.52 ? 67 PHE A CB 1 ATOM 355 C CG . PHE A 1 67 ? -3.298 -10.535 5.820 1.00 18.17 ? 67 PHE A CG 1 ATOM 356 C CD1 . PHE A 1 67 ? -4.543 -10.846 5.308 1.00 21.98 ? 67 PHE A CD1 1 ATOM 357 C CD2 . PHE A 1 67 ? -2.209 -11.305 5.446 1.00 22.51 ? 67 PHE A CD2 1 ATOM 358 C CE1 . PHE A 1 67 ? -4.705 -11.911 4.437 1.00 18.33 ? 67 PHE A CE1 1 ATOM 359 C CE2 . PHE A 1 67 ? -2.378 -12.374 4.583 1.00 21.99 ? 67 PHE A CE2 1 ATOM 360 C CZ . PHE A 1 67 ? -3.630 -12.666 4.079 1.00 21.33 ? 67 PHE A CZ 1 ATOM 361 N N . PRO A 1 68 ? -3.948 -8.127 3.676 1.00 16.38 ? 68 PRO A N 1 ATOM 362 C CA . PRO A 1 68 ? -2.696 -8.596 3.065 1.00 17.28 ? 68 PRO A CA 1 ATOM 363 C C . PRO A 1 68 ? -1.736 -7.424 2.832 1.00 20.66 ? 68 PRO A C 1 ATOM 364 O O . PRO A 1 68 ? -2.176 -6.279 2.681 1.00 17.45 ? 68 PRO A O 1 ATOM 365 C CB . PRO A 1 68 ? -3.156 -9.213 1.740 1.00 18.02 ? 68 PRO A CB 1 ATOM 366 C CG . PRO A 1 68 ? -4.402 -8.343 1.348 1.00 17.18 ? 68 PRO A CG 1 ATOM 367 C CD . PRO A 1 68 ? -5.059 -8.040 2.695 1.00 17.13 ? 68 PRO A CD 1 ATOM 368 N N . SER A 1 69 ? -0.432 -7.692 2.798 1.00 15.27 ? 69 SER A N 1 ATOM 369 C CA . SER A 1 69 ? 0.543 -6.604 2.677 1.00 18.80 ? 69 SER A CA 1 ATOM 370 C C . SER A 1 69 ? 0.728 -6.214 1.206 1.00 16.35 ? 69 SER A C 1 ATOM 371 O O . SER A 1 69 ? 1.821 -6.274 0.644 1.00 18.78 ? 69 SER A O 1 ATOM 372 C CB . SER A 1 69 ? 1.858 -6.993 3.341 1.00 19.00 ? 69 SER A CB 1 ATOM 373 O OG . SER A 1 69 ? 2.341 -8.243 2.880 1.00 21.26 ? 69 SER A OG 1 ATOM 374 N N . LEU A 1 70 ? -0.395 -5.813 0.590 1.00 18.44 ? 70 LEU A N 1 ATOM 375 C CA . LEU A 1 70 ? -0.512 -5.358 -0.794 1.00 17.47 ? 70 LEU A CA 1 ATOM 376 C C . LEU A 1 70 ? -0.939 -3.892 -0.825 1.00 19.08 ? 70 LEU A C 1 ATOM 377 O O . LEU A 1 70 ? -1.395 -3.340 0.177 1.00 17.16 ? 70 LEU A O 1 ATOM 378 C CB . LEU A 1 70 ? -1.546 -6.191 -1.575 1.00 17.82 ? 70 LEU A CB 1 ATOM 379 C CG . LEU A 1 70 ? -1.300 -7.698 -1.584 1.00 18.25 ? 70 LEU A CG 1 ATOM 380 C CD1 . LEU A 1 70 ? -2.501 -8.413 -2.186 1.00 20.19 ? 70 LEU A CD1 1 ATOM 381 C CD2 . LEU A 1 70 ? -0.037 -7.980 -2.386 1.00 19.57 ? 70 LEU A CD2 1 ATOM 382 N N . SER A 1 71 ? -0.839 -3.282 -2.013 1.00 19.27 ? 71 SER A N 1 ATOM 383 C CA . SER A 1 71 ? -1.086 -1.845 -2.207 1.00 17.07 ? 71 SER A CA 1 ATOM 384 C C . SER A 1 71 ? -2.488 -1.346 -1.900 1.00 17.49 ? 71 SER A C 1 ATOM 385 O O . SER A 1 71 ? -2.687 -0.575 -0.952 1.00 17.11 ? 71 SER A O 1 ATOM 386 C CB . SER A 1 71 ? -0.787 -1.443 -3.651 1.00 22.30 ? 71 SER A CB 1 ATOM 387 O OG . SER A 1 71 ? 0.602 -1.255 -3.780 1.00 33.20 ? 71 SER A OG 1 ATOM 388 N N . TYR A 1 72 ? -3.448 -1.667 -2.762 1.00 17.02 ? 72 TYR A N 1 ATOM 389 C CA . TYR A 1 72 ? -4.784 -1.105 -2.574 1.00 16.67 ? 72 TYR A CA 1 ATOM 390 C C . TYR A 1 72 ? -5.332 -1.358 -1.176 1.00 18.11 ? 72 TYR A C 1 ATOM 391 O O . TYR A 1 72 ? -5.863 -0.403 -0.574 1.00 15.77 ? 72 TYR A O 1 ATOM 392 C CB . TYR A 1 72 ? -5.732 -1.609 -3.682 1.00 19.00 ? 72 TYR A CB 1 ATOM 393 C CG . TYR A 1 72 ? -5.591 -0.816 -4.960 1.00 20.41 ? 72 TYR A CG 1 ATOM 394 C CD1 . TYR A 1 72 ? -6.113 0.478 -5.058 1.00 19.91 ? 72 TYR A CD1 1 ATOM 395 C CD2 . TYR A 1 72 ? -4.911 -1.331 -6.052 1.00 17.46 ? 72 TYR A CD2 1 ATOM 396 C CE1 . TYR A 1 72 ? -5.968 1.222 -6.215 1.00 18.34 ? 72 TYR A CE1 1 ATOM 397 C CE2 . TYR A 1 72 ? -4.767 -0.602 -7.218 1.00 20.71 ? 72 TYR A CE2 1 ATOM 398 C CZ . TYR A 1 72 ? -5.310 0.672 -7.301 1.00 23.16 ? 72 TYR A CZ 1 ATOM 399 O OH . TYR A 1 72 ? -5.150 1.377 -8.459 1.00 21.47 ? 72 TYR A OH 1 ATOM 400 N N . PRO A 1 73 ? -5.229 -2.561 -0.587 1.00 16.72 ? 73 PRO A N 1 ATOM 401 C CA . PRO A 1 73 ? -5.633 -2.691 0.825 1.00 16.27 ? 73 PRO A CA 1 ATOM 402 C C . PRO A 1 73 ? -4.947 -1.697 1.757 1.00 15.31 ? 73 PRO A C 1 ATOM 403 O O . PRO A 1 73 ? -5.624 -1.055 2.571 1.00 16.96 ? 73 PRO A O 1 ATOM 404 C CB . PRO A 1 73 ? -5.262 -4.152 1.161 1.00 16.23 ? 73 PRO A CB 1 ATOM 405 C CG . PRO A 1 73 ? -5.396 -4.882 -0.161 1.00 18.43 ? 73 PRO A CG 1 ATOM 406 C CD . PRO A 1 73 ? -4.866 -3.872 -1.176 1.00 18.20 ? 73 PRO A CD 1 ATOM 407 N N . ASN A 1 74 ? -3.618 -1.573 1.699 1.00 13.95 ? 74 ASN A N 1 ATOM 408 C CA . ASN A 1 74 ? -2.960 -0.688 2.655 1.00 12.67 ? 74 ASN A CA 1 ATOM 409 C C . ASN A 1 74 ? -3.105 0.794 2.316 1.00 17.44 ? 74 ASN A C 1 ATOM 410 O O . ASN A 1 74 ? -3.129 1.613 3.239 1.00 16.00 ? 74 ASN A O 1 ATOM 411 C CB . ASN A 1 74 ? -1.498 -1.086 2.808 1.00 14.91 ? 74 ASN A CB 1 ATOM 412 C CG . ASN A 1 74 ? -1.356 -2.235 3.782 1.00 16.82 ? 74 ASN A CG 1 ATOM 413 O OD1 . ASN A 1 74 ? -1.247 -2.023 4.980 1.00 19.74 ? 74 ASN A OD1 1 ATOM 414 N ND2 . ASN A 1 74 ? -1.430 -3.458 3.274 1.00 17.35 ? 74 ASN A ND2 1 ATOM 415 N N . TYR A 1 75 ? -3.230 1.166 1.037 1.00 16.87 ? 75 TYR A N 1 ATOM 416 C CA . TYR A 1 75 ? -3.590 2.553 0.735 1.00 16.48 ? 75 TYR A CA 1 ATOM 417 C C . TYR A 1 75 ? -4.813 2.963 1.539 1.00 17.38 ? 75 TYR A C 1 ATOM 418 O O . TYR A 1 75 ? -4.861 4.060 2.114 1.00 16.35 ? 75 TYR A O 1 ATOM 419 C CB . TYR A 1 75 ? -3.917 2.760 -0.747 1.00 15.24 ? 75 TYR A CB 1 ATOM 420 C CG . TYR A 1 75 ? -2.864 2.451 -1.764 1.00 16.12 ? 75 TYR A CG 1 ATOM 421 C CD1 . TYR A 1 75 ? -1.509 2.401 -1.431 1.00 14.19 ? 75 TYR A CD1 1 ATOM 422 C CD2 . TYR A 1 75 ? -3.232 2.199 -3.083 1.00 17.75 ? 75 TYR A CD2 1 ATOM 423 C CE1 . TYR A 1 75 ? -0.554 2.118 -2.404 1.00 18.79 ? 75 TYR A CE1 1 ATOM 424 C CE2 . TYR A 1 75 ? -2.303 1.927 -4.041 1.00 16.23 ? 75 TYR A CE2 1 ATOM 425 C CZ . TYR A 1 75 ? -0.969 1.880 -3.716 1.00 20.54 ? 75 TYR A CZ 1 ATOM 426 O OH . TYR A 1 75 ? -0.067 1.576 -4.720 1.00 21.86 ? 75 TYR A OH 1 ATOM 427 N N . TYR A 1 76 ? -5.835 2.101 1.549 1.00 15.08 ? 76 TYR A N 1 ATOM 428 C CA . TYR A 1 76 ? -7.089 2.434 2.210 1.00 16.80 ? 76 TYR A CA 1 ATOM 429 C C . TYR A 1 76 ? -6.981 2.287 3.712 1.00 16.19 ? 76 TYR A C 1 ATOM 430 O O . TYR A 1 76 ? -7.552 3.088 4.450 1.00 18.03 ? 76 TYR A O 1 ATOM 431 C CB . TYR A 1 76 ? -8.244 1.572 1.672 1.00 13.96 ? 76 TYR A CB 1 ATOM 432 C CG . TYR A 1 76 ? -9.384 2.437 1.152 1.00 14.78 ? 76 TYR A CG 1 ATOM 433 C CD1 . TYR A 1 76 ? -9.121 3.578 0.390 1.00 19.39 ? 76 TYR A CD1 1 ATOM 434 C CD2 . TYR A 1 76 ? -10.708 2.100 1.398 1.00 16.32 ? 76 TYR A CD2 1 ATOM 435 C CE1 . TYR A 1 76 ? -10.178 4.400 -0.107 1.00 17.60 ? 76 TYR A CE1 1 ATOM 436 C CE2 . TYR A 1 76 ? -11.762 2.905 0.921 1.00 18.63 ? 76 TYR A CE2 1 ATOM 437 C CZ . TYR A 1 76 ? -11.486 4.037 0.175 1.00 20.05 ? 76 TYR A CZ 1 ATOM 438 O OH . TYR A 1 76 ? -12.535 4.818 -0.314 1.00 17.00 ? 76 TYR A OH 1 ATOM 439 N N . THR A 1 77 ? -6.180 1.343 4.200 1.00 14.22 ? 77 THR A N 1 ATOM 440 C CA . THR A 1 77 ? -5.944 1.321 5.637 1.00 15.53 ? 77 THR A CA 1 ATOM 441 C C . THR A 1 77 ? -5.306 2.627 6.111 1.00 18.13 ? 77 THR A C 1 ATOM 442 O O . THR A 1 77 ? -5.740 3.217 7.110 1.00 17.79 ? 77 THR A O 1 ATOM 443 C CB . THR A 1 77 ? -5.060 0.131 6.003 1.00 17.21 ? 77 THR A CB 1 ATOM 444 O OG1 . THR A 1 77 ? -5.728 -1.074 5.654 1.00 18.82 ? 77 THR A OG1 1 ATOM 445 C CG2 . THR A 1 77 ? -4.786 0.141 7.498 1.00 20.03 ? 77 THR A CG2 1 ATOM 446 N N . LEU A 1 78 ? -4.272 3.097 5.397 1.00 17.22 ? 78 LEU A N 1 ATOM 447 C CA . LEU A 1 78 ? -3.569 4.319 5.794 1.00 17.13 ? 78 LEU A CA 1 ATOM 448 C C . LEU A 1 78 ? -4.510 5.517 5.825 1.00 18.75 ? 78 LEU A C 1 ATOM 449 O O . LEU A 1 78 ? -4.468 6.321 6.762 1.00 17.88 ? 78 LEU A O 1 ATOM 450 C CB . LEU A 1 78 ? -2.396 4.589 4.845 1.00 14.03 ? 78 LEU A CB 1 ATOM 451 C CG . LEU A 1 78 ? -1.232 3.599 4.967 1.00 18.29 ? 78 LEU A CG 1 ATOM 452 C CD1 . LEU A 1 78 ? -0.399 3.587 3.680 1.00 18.32 ? 78 LEU A CD1 1 ATOM 453 C CD2 . LEU A 1 78 ? -0.365 3.938 6.184 1.00 18.28 ? 78 LEU A CD2 1 ATOM 454 N N . MET A 1 79 ? -5.369 5.645 4.823 1.00 18.78 ? 79 MET A N 1 ATOM 455 C CA . MET A 1 79 ? -6.204 6.839 4.702 1.00 18.26 ? 79 MET A CA 1 ATOM 456 C C . MET A 1 79 ? -7.559 6.715 5.403 1.00 20.01 ? 79 MET A C 1 ATOM 457 O O . MET A 1 79 ? -8.373 7.649 5.322 1.00 19.60 ? 79 MET A O 1 ATOM 458 C CB . MET A 1 79 ? -6.393 7.170 3.221 1.00 16.46 ? 79 MET A CB 1 ATOM 459 C CG . MET A 1 79 ? -5.226 7.939 2.630 1.00 17.62 ? 79 MET A CG 1 ATOM 460 S SD . MET A 1 79 ? -5.281 9.671 3.293 1.00 25.32 ? 79 MET A SD 1 ATOM 461 C CE . MET A 1 79 ? -3.744 10.337 2.652 1.00 23.29 ? 79 MET A CE 1 ATOM 462 N N . THR A 1 80 ? -7.838 5.590 6.069 1.00 19.15 ? 80 THR A N 1 ATOM 463 C CA . THR A 1 80 ? -9.062 5.434 6.856 1.00 18.98 ? 80 THR A CA 1 ATOM 464 C C . THR A 1 80 ? -8.826 5.107 8.319 1.00 20.31 ? 80 THR A C 1 ATOM 465 O O . THR A 1 80 ? -9.758 5.249 9.118 1.00 21.34 ? 80 THR A O 1 ATOM 466 C CB . THR A 1 80 ? -9.966 4.312 6.302 1.00 20.54 ? 80 THR A CB 1 ATOM 467 O OG1 . THR A 1 80 ? -9.314 3.043 6.464 1.00 18.52 ? 80 THR A OG1 1 ATOM 468 C CG2 . THR A 1 80 ? -10.326 4.529 4.849 1.00 17.63 ? 80 THR A CG2 1 ATOM 469 N N . GLY A 1 81 ? -7.629 4.665 8.696 1.00 20.06 ? 81 GLY A N 1 ATOM 470 C CA . GLY A 1 81 ? -7.418 4.154 10.032 1.00 20.03 ? 81 GLY A CA 1 ATOM 471 C C . GLY A 1 81 ? -8.140 2.867 10.366 1.00 22.82 ? 81 GLY A C 1 ATOM 472 O O . GLY A 1 81 ? -8.216 2.509 11.546 1.00 21.16 ? 81 GLY A O 1 ATOM 473 N N . ARG A 1 82 ? -8.656 2.145 9.370 1.00 20.09 ? 82 ARG A N 1 ATOM 474 C CA . ARG A 1 82 ? -9.480 0.965 9.597 1.00 18.45 ? 82 ARG A CA 1 ATOM 475 C C . ARG A 1 82 ? -8.857 -0.256 8.936 1.00 21.09 ? 82 ARG A C 1 ATOM 476 O O . ARG A 1 82 ? -8.176 -0.136 7.916 1.00 19.29 ? 82 ARG A O 1 ATOM 477 C CB . ARG A 1 82 ? -10.881 1.183 9.044 1.00 21.65 ? 82 ARG A CB 1 ATOM 478 C CG . ARG A 1 82 ? -11.595 2.350 9.708 1.00 22.93 ? 82 ARG A CG 1 ATOM 479 C CD . ARG A 1 82 ? -12.900 2.695 9.010 1.00 18.78 ? 82 ARG A CD 1 ATOM 480 N NE . ARG A 1 82 ? -13.719 3.554 9.864 1.00 20.57 ? 82 ARG A NE 1 ATOM 481 C CZ . ARG A 1 82 ? -15.024 3.748 9.717 1.00 28.55 ? 82 ARG A CZ 1 ATOM 482 N NH1 . ARG A 1 82 ? -15.691 3.139 8.741 1.00 23.97 ? 82 ARG A NH1 1 ATOM 483 N NH2 . ARG A 1 82 ? -15.663 4.559 10.559 1.00 28.59 ? 82 ARG A NH2 1 ATOM 484 N N . HIS A 1 83 ? -9.088 -1.429 9.536 1.00 19.24 ? 83 HIS A N 1 ATOM 485 C CA . HIS A 1 83 ? -8.635 -2.699 8.976 1.00 21.28 ? 83 HIS A CA 1 ATOM 486 C C . HIS A 1 83 ? -9.398 -3.042 7.693 1.00 20.86 ? 83 HIS A C 1 ATOM 487 O O . HIS A 1 83 ? -10.493 -2.534 7.434 1.00 20.98 ? 83 HIS A O 1 ATOM 488 C CB . HIS A 1 83 ? -8.802 -3.828 9.998 1.00 20.65 ? 83 HIS A CB 1 ATOM 489 C CG . HIS A 1 83 ? -7.928 -3.688 11.202 1.00 23.69 ? 83 HIS A CG 1 ATOM 490 N ND1 . HIS A 1 83 ? -6.549 -3.740 11.132 1.00 25.24 ? 83 HIS A ND1 1 ATOM 491 C CD2 . HIS A 1 83 ? -8.235 -3.539 12.512 1.00 25.31 ? 83 HIS A CD2 1 ATOM 492 C CE1 . HIS A 1 83 ? -6.047 -3.602 12.346 1.00 26.18 ? 83 HIS A CE1 1 ATOM 493 N NE2 . HIS A 1 83 ? -7.048 -3.482 13.201 1.00 25.08 ? 83 HIS A NE2 1 ATOM 494 N N . CYS A 1 84 ? -8.789 -3.906 6.863 1.00 18.62 ? 84 CYS A N 1 ATOM 495 C CA . CYS A 1 84 ? -9.353 -4.159 5.534 1.00 18.49 ? 84 CYS A CA 1 ATOM 496 C C . CYS A 1 84 ? -10.725 -4.816 5.595 1.00 19.67 ? 84 CYS A C 1 ATOM 497 O O . CYS A 1 84 ? -11.569 -4.555 4.725 1.00 19.96 ? 84 CYS A O 1 ATOM 498 C CB . CYS A 1 84 ? -8.414 -5.029 4.696 1.00 21.96 ? 84 CYS A CB 1 ATOM 499 S SG . CYS A 1 84 ? -6.814 -4.285 4.408 1.00 22.25 ? 84 CYS A SG 1 ATOM 500 N N . GLU A 1 85 ? -10.985 -5.649 6.609 1.00 20.48 ? 85 GLU A N 1 ATOM 501 C CA . GLU A 1 85 ? -12.330 -6.214 6.743 1.00 19.52 ? 85 GLU A CA 1 ATOM 502 C C . GLU A 1 85 ? -13.373 -5.147 7.034 1.00 20.49 ? 85 GLU A C 1 ATOM 503 O O . GLU A 1 85 ? -14.572 -5.424 6.891 1.00 21.15 ? 85 GLU A O 1 ATOM 504 C CB . GLU A 1 85 ? -12.378 -7.283 7.849 1.00 18.12 ? 85 GLU A CB 1 ATOM 505 C CG . GLU A 1 85 ? -12.406 -6.706 9.276 1.00 19.05 ? 85 GLU A CG 1 ATOM 506 C CD . GLU A 1 85 ? -12.247 -7.774 10.348 1.00 24.60 ? 85 GLU A CD 1 ATOM 507 O OE1 . GLU A 1 85 ? -12.379 -8.975 10.020 1.00 20.29 ? 85 GLU A OE1 1 ATOM 508 O OE2 . GLU A 1 85 ? -11.976 -7.400 11.512 1.00 25.77 ? 85 GLU A OE2 1 ATOM 509 N N . VAL A 1 86 ? -12.950 -3.943 7.423 1.00 19.63 ? 86 VAL A N 1 ATOM 510 C CA . VAL A 1 86 ? -13.865 -2.827 7.659 1.00 17.90 ? 86 VAL A CA 1 ATOM 511 C C . VAL A 1 86 ? -13.987 -1.935 6.428 1.00 20.34 ? 86 VAL A C 1 ATOM 512 O O . VAL A 1 86 ? -15.094 -1.626 5.980 1.00 20.23 ? 86 VAL A O 1 ATOM 513 C CB . VAL A 1 86 ? -13.415 -2.017 8.897 1.00 21.87 ? 86 VAL A CB 1 ATOM 514 C CG1 . VAL A 1 86 ? -14.333 -0.821 9.135 1.00 22.38 ? 86 VAL A CG1 1 ATOM 515 C CG2 . VAL A 1 86 ? -13.374 -2.906 10.153 1.00 23.70 ? 86 VAL A CG2 1 ATOM 516 N N . HIS A 1 87 ? -12.870 -1.466 5.862 1.00 19.27 ? 87 HIS A N 1 ATOM 517 C CA . HIS A 1 87 ? -12.988 -0.560 4.724 1.00 18.74 ? 87 HIS A CA 1 ATOM 518 C C . HIS A 1 87 ? -13.256 -1.290 3.408 1.00 19.97 ? 87 HIS A C 1 ATOM 519 O O . HIS A 1 87 ? -13.599 -0.631 2.419 1.00 17.42 ? 87 HIS A O 1 ATOM 520 C CB . HIS A 1 87 ? -11.753 0.353 4.620 1.00 21.53 ? 87 HIS A CB 1 ATOM 521 C CG . HIS A 1 87 ? -10.451 -0.346 4.336 1.00 20.93 ? 87 HIS A CG 1 ATOM 522 N ND1 . HIS A 1 87 ? -10.240 -1.122 3.218 1.00 15.03 ? 87 HIS A ND1 1 ATOM 523 C CD2 . HIS A 1 87 ? -9.269 -0.312 4.998 1.00 18.11 ? 87 HIS A CD2 1 ATOM 524 C CE1 . HIS A 1 87 ? -8.990 -1.553 3.211 1.00 16.47 ? 87 HIS A CE1 1 ATOM 525 N NE2 . HIS A 1 87 ? -8.380 -1.080 4.286 1.00 16.65 ? 87 HIS A NE2 1 ATOM 526 N N . GLN A 1 88 ? -13.119 -2.621 3.391 1.00 18.94 ? 88 GLN A N 1 ATOM 527 C CA . GLN A 1 88 ? -13.580 -3.582 2.392 1.00 16.05 ? 88 GLN A CA 1 ATOM 528 C C . GLN A 1 88 ? -12.627 -3.768 1.217 1.00 20.30 ? 88 GLN A C 1 ATOM 529 O O . GLN A 1 88 ? -12.876 -4.648 0.393 1.00 19.55 ? 88 GLN A O 1 ATOM 530 C CB . GLN A 1 88 ? -14.977 -3.248 1.831 1.00 17.00 ? 88 GLN A CB 1 ATOM 531 C CG . GLN A 1 88 ? -16.027 -3.045 2.913 1.00 21.78 ? 88 GLN A CG 1 ATOM 532 C CD . GLN A 1 88 ? -16.362 -4.323 3.688 1.00 22.21 ? 88 GLN A CD 1 ATOM 533 O OE1 . GLN A 1 88 ? -16.100 -5.429 3.230 1.00 21.57 ? 88 GLN A OE1 1 ATOM 534 N NE2 . GLN A 1 88 ? -16.971 -4.159 4.862 1.00 22.73 ? 88 GLN A NE2 1 ATOM 535 N N . MET A 1 89 ? -11.555 -2.988 1.094 1.00 17.02 ? 89 MET A N 1 ATOM 536 C CA . MET A 1 89 ? -10.605 -3.184 -0.003 1.00 16.07 ? 89 MET A CA 1 ATOM 537 C C . MET A 1 89 ? -9.627 -4.274 0.430 1.00 17.55 ? 89 MET A C 1 ATOM 538 O O . MET A 1 89 ? -8.574 -4.009 1.000 1.00 17.75 ? 89 MET A O 1 ATOM 539 C CB . MET A 1 89 ? -9.933 -1.866 -0.373 1.00 16.24 ? 89 MET A CB 1 ATOM 540 C CG . MET A 1 89 ? -10.995 -0.842 -0.805 1.00 19.06 ? 89 MET A CG 1 ATOM 541 S SD . MET A 1 89 ? -10.420 0.585 -1.747 1.00 19.10 ? 89 MET A SD 1 ATOM 542 C CE . MET A 1 89 ? -10.248 -0.173 -3.361 1.00 18.32 ? 89 MET A CE 1 ATOM 543 N N . ILE A 1 90 ? -10.011 -5.529 0.180 1.00 16.68 ? 90 ILE A N 1 ATOM 544 C CA . ILE A 1 90 ? -9.309 -6.665 0.783 1.00 15.73 ? 90 ILE A CA 1 ATOM 545 C C . ILE A 1 90 ? -8.281 -7.276 -0.154 1.00 19.67 ? 90 ILE A C 1 ATOM 546 O O . ILE A 1 90 ? -7.502 -8.146 0.281 1.00 19.74 ? 90 ILE A O 1 ATOM 547 C CB . ILE A 1 90 ? -10.305 -7.738 1.285 1.00 18.68 ? 90 ILE A CB 1 ATOM 548 C CG1 . ILE A 1 90 ? -11.341 -8.119 0.220 1.00 19.34 ? 90 ILE A CG1 1 ATOM 549 C CG2 . ILE A 1 90 ? -11.006 -7.257 2.555 1.00 19.63 ? 90 ILE A CG2 1 ATOM 550 C CD1 . ILE A 1 90 ? -10.902 -9.297 -0.683 1.00 20.38 ? 90 ILE A CD1 1 ATOM 551 N N . GLY A 1 91 ? -8.225 -6.842 -1.412 1.00 18.25 ? 91 GLY A N 1 ATOM 552 C CA . GLY A 1 91 ? -7.189 -7.320 -2.312 1.00 17.79 ? 91 GLY A CA 1 ATOM 553 C C . GLY A 1 91 ? -6.834 -6.291 -3.364 1.00 18.67 ? 91 GLY A C 1 ATOM 554 O O . GLY A 1 91 ? -7.558 -5.312 -3.580 1.00 20.59 ? 91 GLY A O 1 ATOM 555 N N . ASN A 1 92 ? -5.694 -6.525 -4.023 1.00 20.08 ? 92 ASN A N 1 ATOM 556 C CA . ASN A 1 92 ? -5.404 -5.826 -5.274 1.00 20.65 ? 92 ASN A CA 1 ATOM 557 C C . ASN A 1 92 ? -6.353 -6.267 -6.377 1.00 19.38 ? 92 ASN A C 1 ATOM 558 O O . ASN A 1 92 ? -6.650 -5.484 -7.287 1.00 18.22 ? 92 ASN A O 1 ATOM 559 C CB . ASN A 1 92 ? -3.964 -6.092 -5.737 1.00 17.00 ? 92 ASN A CB 1 ATOM 560 C CG . ASN A 1 92 ? -2.957 -5.176 -5.083 1.00 21.60 ? 92 ASN A CG 1 ATOM 561 O OD1 . ASN A 1 92 ? -3.314 -4.106 -4.592 1.00 17.56 ? 92 ASN A OD1 1 ATOM 562 N ND2 . ASN A 1 92 ? -1.688 -5.591 -5.078 1.00 18.31 ? 92 ASN A ND2 1 ATOM 563 N N . TYR A 1 93 ? -6.795 -7.520 -6.325 1.00 17.38 ? 93 TYR A N 1 ATOM 564 C CA . TYR A 1 93 ? -7.786 -8.080 -7.237 1.00 21.80 ? 93 TYR A CA 1 ATOM 565 C C . TYR A 1 93 ? -8.968 -8.609 -6.434 1.00 19.59 ? 93 TYR A C 1 ATOM 566 O O . TYR A 1 93 ? -8.781 -9.366 -5.476 1.00 22.14 ? 93 TYR A O 1 ATOM 567 C CB . TYR A 1 93 ? -7.198 -9.209 -8.089 1.00 21.05 ? 93 TYR A CB 1 ATOM 568 C CG . TYR A 1 93 ? -6.059 -8.805 -8.991 1.00 21.10 ? 93 TYR A CG 1 ATOM 569 C CD1 . TYR A 1 93 ? -4.783 -8.620 -8.479 1.00 23.30 ? 93 TYR A CD1 1 ATOM 570 C CD2 . TYR A 1 93 ? -6.251 -8.646 -10.364 1.00 22.60 ? 93 TYR A CD2 1 ATOM 571 C CE1 . TYR A 1 93 ? -3.725 -8.267 -9.295 1.00 26.41 ? 93 TYR A CE1 1 ATOM 572 C CE2 . TYR A 1 93 ? -5.198 -8.287 -11.194 1.00 23.60 ? 93 TYR A CE2 1 ATOM 573 C CZ . TYR A 1 93 ? -3.937 -8.100 -10.647 1.00 28.49 ? 93 TYR A CZ 1 ATOM 574 O OH . TYR A 1 93 ? -2.870 -7.752 -11.442 1.00 33.03 ? 93 TYR A OH 1 ATOM 575 N N . MET A 1 94 ? -10.182 -8.219 -6.827 1.00 18.87 ? 94 MET A N 1 ATOM 576 C CA . MET A 1 94 ? -11.400 -8.595 -6.127 1.00 16.79 ? 94 MET A CA 1 ATOM 577 C C . MET A 1 94 ? -12.498 -8.889 -7.143 1.00 19.63 ? 94 MET A C 1 ATOM 578 O O . MET A 1 94 ? -12.482 -8.387 -8.269 1.00 19.46 ? 94 MET A O 1 ATOM 579 C CB . MET A 1 94 ? -11.892 -7.499 -5.167 1.00 19.65 ? 94 MET A CB 1 ATOM 580 C CG . MET A 1 94 ? -10.850 -7.088 -4.125 1.00 20.11 ? 94 MET A CG 1 ATOM 581 S SD . MET A 1 94 ? -11.460 -5.816 -3.002 1.00 20.92 ? 94 MET A SD 1 ATOM 582 C CE . MET A 1 94 ? -11.427 -4.378 -4.067 1.00 20.06 ? 94 MET A CE 1 ATOM 583 N N . TRP A 1 95 ? -13.462 -9.699 -6.711 1.00 19.59 ? 95 TRP A N 1 ATOM 584 C CA . TRP A 1 95 ? -14.599 -10.082 -7.534 1.00 19.14 ? 95 TRP A CA 1 ATOM 585 C C . TRP A 1 95 ? -15.861 -10.002 -6.695 1.00 20.00 ? 95 TRP A C 1 ATOM 586 O O . TRP A 1 95 ? -15.879 -10.423 -5.539 1.00 22.96 ? 95 TRP A O 1 ATOM 587 C CB . TRP A 1 95 ? -14.434 -11.486 -8.109 1.00 22.94 ? 95 TRP A CB 1 ATOM 588 C CG . TRP A 1 95 ? -15.551 -11.916 -9.041 1.00 25.42 ? 95 TRP A CG 1 ATOM 589 C CD1 . TRP A 1 95 ? -15.937 -11.304 -10.205 1.00 24.35 ? 95 TRP A CD1 1 ATOM 590 C CD2 . TRP A 1 95 ? -16.402 -13.068 -8.891 1.00 23.23 ? 95 TRP A CD2 1 ATOM 591 N NE1 . TRP A 1 95 ? -16.984 -11.999 -10.781 1.00 28.45 ? 95 TRP A NE1 1 ATOM 592 C CE2 . TRP A 1 95 ? -17.285 -13.085 -9.994 1.00 28.50 ? 95 TRP A CE2 1 ATOM 593 C CE3 . TRP A 1 95 ? -16.511 -14.076 -7.923 1.00 24.95 ? 95 TRP A CE3 1 ATOM 594 C CZ2 . TRP A 1 95 ? -18.262 -14.084 -10.163 1.00 27.63 ? 95 TRP A CZ2 1 ATOM 595 C CZ3 . TRP A 1 95 ? -17.478 -15.073 -8.095 1.00 28.49 ? 95 TRP A CZ3 1 ATOM 596 C CH2 . TRP A 1 95 ? -18.339 -15.066 -9.207 1.00 31.62 ? 95 TRP A CH2 1 ATOM 597 N N . ASP A 1 96 ? -16.917 -9.456 -7.283 1.00 21.36 ? 96 ASP A N 1 ATOM 598 C CA . ASP A 1 96 ? -18.212 -9.425 -6.625 1.00 24.97 ? 96 ASP A CA 1 ATOM 599 C C . ASP A 1 96 ? -19.152 -10.399 -7.332 1.00 27.78 ? 96 ASP A C 1 ATOM 600 O O . ASP A 1 96 ? -19.559 -10.134 -8.472 1.00 27.13 ? 96 ASP A O 1 ATOM 601 C CB . ASP A 1 96 ? -18.786 -8.009 -6.649 1.00 28.47 ? 96 ASP A CB 1 ATOM 602 C CG . ASP A 1 96 ? -20.189 -7.949 -6.101 1.00 34.83 ? 96 ASP A CG 1 ATOM 603 O OD1 . ASP A 1 96 ? -20.505 -8.743 -5.197 1.00 36.53 ? 96 ASP A OD1 1 ATOM 604 O OD2 . ASP A 1 96 ? -20.975 -7.109 -6.585 1.00 39.01 ? 96 ASP A OD2 1 ATOM 605 N N . PRO A 1 97 ? -19.503 -11.531 -6.718 1.00 29.00 ? 97 PRO A N 1 ATOM 606 C CA . PRO A 1 97 ? -20.411 -12.478 -7.392 1.00 33.11 ? 97 PRO A CA 1 ATOM 607 C C . PRO A 1 97 ? -21.779 -11.897 -7.693 1.00 35.24 ? 97 PRO A C 1 ATOM 608 O O . PRO A 1 97 ? -22.389 -12.281 -8.696 1.00 42.45 ? 97 PRO A O 1 ATOM 609 C CB . PRO A 1 97 ? -20.511 -13.642 -6.397 1.00 29.73 ? 97 PRO A CB 1 ATOM 610 C CG . PRO A 1 97 ? -19.297 -13.516 -5.527 1.00 34.14 ? 97 PRO A CG 1 ATOM 611 C CD . PRO A 1 97 ? -19.040 -12.039 -5.418 1.00 28.15 ? 97 PRO A CD 1 ATOM 612 N N . ARG A 1 98 ? -22.282 -10.996 -6.847 1.00 34.61 ? 98 ARG A N 1 ATOM 613 C CA . ARG A 1 98 ? -23.601 -10.407 -7.065 1.00 40.24 ? 98 ARG A CA 1 ATOM 614 C C . ARG A 1 98 ? -23.679 -9.732 -8.428 1.00 44.16 ? 98 ARG A C 1 ATOM 615 O O . ARG A 1 98 ? -24.521 -10.072 -9.263 1.00 43.70 ? 98 ARG A O 1 ATOM 616 C CB . ARG A 1 98 ? -23.902 -9.396 -5.960 1.00 34.07 ? 98 ARG A CB 1 ATOM 617 C CG . ARG A 1 98 ? -23.680 -9.917 -4.550 1.00 48.99 ? 98 ARG A CG 1 ATOM 618 C CD . ARG A 1 98 ? -23.499 -8.761 -3.569 1.00 60.42 ? 98 ARG A CD 1 ATOM 619 N NE . ARG A 1 98 ? -23.260 -9.209 -2.196 1.00 71.71 ? 98 ARG A NE 1 ATOM 620 C CZ . ARG A 1 98 ? -22.056 -9.370 -1.648 1.00 71.90 ? 98 ARG A CZ 1 ATOM 621 N NH1 . ARG A 1 98 ? -20.952 -9.123 -2.347 1.00 60.87 ? 98 ARG A NH1 1 ATOM 622 N NH2 . ARG A 1 98 ? -21.956 -9.777 -0.390 1.00 69.11 ? 98 ARG A NH2 1 ATOM 623 N N . THR A 1 99 ? -22.798 -8.768 -8.664 1.00 40.79 ? 99 THR A N 1 ATOM 624 C CA . THR A 1 99 ? -22.783 -7.989 -9.890 1.00 36.95 ? 99 THR A CA 1 ATOM 625 C C . THR A 1 99 ? -21.934 -8.615 -10.988 1.00 40.68 ? 99 THR A C 1 ATOM 626 O O . THR A 1 99 ? -21.992 -8.143 -12.127 1.00 40.42 ? 99 THR A O 1 ATOM 627 C CB . THR A 1 99 ? -22.270 -6.582 -9.590 1.00 44.01 ? 99 THR A CB 1 ATOM 628 O OG1 . THR A 1 99 ? -20.950 -6.672 -9.039 1.00 37.61 ? 99 THR A OG1 1 ATOM 629 C CG2 . THR A 1 99 ? -23.189 -5.884 -8.586 1.00 41.21 ? 99 THR A CG2 1 ATOM 630 N N . ASN A 1 100 ? -21.163 -9.664 -10.676 1.00 32.99 ? 100 ASN A N 1 ATOM 631 C CA . ASN A 1 100 ? -20.216 -10.277 -11.616 1.00 31.90 ? 100 ASN A CA 1 ATOM 632 C C . ASN A 1 100 ? -19.213 -9.255 -12.171 1.00 33.36 ? 100 ASN A C 1 ATOM 633 O O . ASN A 1 100 ? -18.780 -9.348 -13.323 1.00 35.98 ? 100 ASN A O 1 ATOM 634 C CB . ASN A 1 100 ? -20.949 -10.996 -12.753 1.00 36.47 ? 100 ASN A CB 1 ATOM 635 C CG . ASN A 1 100 ? -20.044 -11.919 -13.535 1.00 37.49 ? 100 ASN A CG 1 ATOM 636 O OD1 . ASN A 1 100 ? -18.952 -12.252 -13.086 1.00 41.37 ? 100 ASN A OD1 1 ATOM 637 N ND2 . ASN A 1 100 ? -20.492 -12.340 -14.711 1.00 49.51 ? 100 ASN A ND2 1 ATOM 638 N N . LYS A 1 101 ? -18.819 -8.285 -11.347 1.00 29.85 ? 101 LYS A N 1 ATOM 639 C CA . LYS A 1 101 ? -17.855 -7.256 -11.710 1.00 26.02 ? 101 LYS A CA 1 ATOM 640 C C . LYS A 1 101 ? -16.550 -7.484 -10.952 1.00 23.45 ? 101 LYS A C 1 ATOM 641 O O . LYS A 1 101 ? -16.560 -8.012 -9.842 1.00 21.34 ? 101 LYS A O 1 ATOM 642 C CB . LYS A 1 101 ? -18.393 -5.863 -11.374 1.00 31.64 ? 101 LYS A CB 1 ATOM 643 C CG . LYS A 1 101 ? -19.739 -5.525 -11.999 1.00 35.71 ? 101 LYS A CG 1 ATOM 644 C CD . LYS A 1 101 ? -19.619 -5.265 -13.482 1.00 35.64 ? 101 LYS A CD 1 ATOM 645 C CE . LYS A 1 101 ? -20.950 -4.772 -14.049 1.00 40.68 ? 101 LYS A CE 1 ATOM 646 N NZ . LYS A 1 101 ? -20.900 -4.633 -15.532 1.00 50.79 ? 101 LYS A NZ 1 ATOM 647 N N . SER A 1 102 ? -15.435 -7.051 -11.549 1.00 26.06 ? 102 SER A N 1 ATOM 648 C CA . SER A 1 102 ? -14.103 -7.226 -10.978 1.00 20.31 ? 102 SER A CA 1 ATOM 649 C C . SER A 1 102 ? -13.414 -5.886 -10.740 1.00 23.63 ? 102 SER A C 1 ATOM 650 O O . SER A 1 102 ? -13.655 -4.902 -11.450 1.00 22.23 ? 102 SER A O 1 ATOM 651 C CB . SER A 1 102 ? -13.215 -8.067 -11.895 1.00 25.81 ? 102 SER A CB 1 ATOM 652 O OG . SER A 1 102 ? -13.724 -9.379 -12.031 1.00 24.39 ? 102 SER A OG 1 ATOM 653 N N . PHE A 1 103 ? -12.527 -5.878 -9.740 1.00 20.49 ? 103 PHE A N 1 ATOM 654 C CA . PHE A 1 103 ? -11.560 -4.808 -9.487 1.00 19.76 ? 103 PHE A CA 1 ATOM 655 C C . PHE A 1 103 ? -10.201 -5.429 -9.803 1.00 20.30 ? 103 PHE A C 1 ATOM 656 O O . PHE A 1 103 ? -9.704 -6.242 -9.027 1.00 18.78 ? 103 PHE A O 1 ATOM 657 C CB . PHE A 1 103 ? -11.641 -4.344 -8.033 1.00 18.04 ? 103 PHE A CB 1 ATOM 658 C CG . PHE A 1 103 ? -10.656 -3.251 -7.666 1.00 18.45 ? 103 PHE A CG 1 ATOM 659 C CD1 . PHE A 1 103 ? -9.350 -3.556 -7.269 1.00 17.83 ? 103 PHE A CD1 1 ATOM 660 C CD2 . PHE A 1 103 ? -11.047 -1.932 -7.670 1.00 20.73 ? 103 PHE A CD2 1 ATOM 661 C CE1 . PHE A 1 103 ? -8.446 -2.557 -6.925 1.00 21.40 ? 103 PHE A CE1 1 ATOM 662 C CE2 . PHE A 1 103 ? -10.152 -0.928 -7.330 1.00 17.42 ? 103 PHE A CE2 1 ATOM 663 C CZ . PHE A 1 103 ? -8.845 -1.237 -6.962 1.00 20.66 ? 103 PHE A CZ 1 ATOM 664 N N . ASP A 1 104 ? -9.627 -5.115 -10.963 1.00 20.48 ? 104 ASP A N 1 ATOM 665 C CA . ASP A 1 104 ? -8.367 -5.758 -11.365 1.00 21.16 ? 104 ASP A CA 1 ATOM 666 C C . ASP A 1 104 ? -7.233 -4.746 -11.222 1.00 20.00 ? 104 ASP A C 1 ATOM 667 O O . ASP A 1 104 ? -6.800 -4.102 -12.179 1.00 21.52 ? 104 ASP A O 1 ATOM 668 C CB . ASP A 1 104 ? -8.469 -6.328 -12.777 1.00 23.10 ? 104 ASP A CB 1 ATOM 669 C CG . ASP A 1 104 ? -9.412 -7.532 -12.850 1.00 28.70 ? 104 ASP A CG 1 ATOM 670 O OD1 . ASP A 1 104 ? -9.547 -8.246 -11.832 1.00 26.85 ? 104 ASP A OD1 1 ATOM 671 O OD2 . ASP A 1 104 ? -10.018 -7.762 -13.918 1.00 29.58 ? 104 ASP A OD2 1 ATOM 672 N N . ILE A 1 105 ? -6.738 -4.646 -9.984 1.00 18.18 ? 105 ILE A N 1 ATOM 673 C CA . ILE A 1 105 ? -5.672 -3.749 -9.531 1.00 16.74 ? 105 ILE A CA 1 ATOM 674 C C . ILE A 1 105 ? -5.801 -2.370 -10.171 1.00 18.52 ? 105 ILE A C 1 ATOM 675 O O . ILE A 1 105 ? -4.818 -1.729 -10.550 1.00 18.18 ? 105 ILE A O 1 ATOM 676 C CB . ILE A 1 105 ? -4.278 -4.416 -9.710 1.00 22.33 ? 105 ILE A CB 1 ATOM 677 C CG1 . ILE A 1 105 ? -3.250 -3.751 -8.785 1.00 19.11 ? 105 ILE A CG1 1 ATOM 678 C CG2 . ILE A 1 105 ? -3.795 -4.483 -11.180 1.00 25.29 ? 105 ILE A CG2 1 ATOM 679 C CD1 . ILE A 1 105 ? -1.913 -4.459 -8.724 1.00 20.36 ? 105 ILE A CD1 1 ATOM 680 N N . GLY A 1 106 ? -7.036 -1.872 -10.225 1.00 20.90 ? 106 GLY A N 1 ATOM 681 C CA . GLY A 1 106 ? -7.295 -0.520 -10.681 1.00 23.97 ? 106 GLY A CA 1 ATOM 682 C C . GLY A 1 106 ? -7.230 -0.280 -12.173 1.00 26.35 ? 106 GLY A C 1 ATOM 683 O O . GLY A 1 106 ? -7.397 0.874 -12.594 1.00 28.55 ? 106 GLY A O 1 ATOM 684 N N . VAL A 1 107 ? -7.005 -1.309 -12.991 1.00 24.32 ? 107 VAL A N 1 ATOM 685 C CA . VAL A 1 107 ? -6.752 -1.095 -14.422 1.00 22.37 ? 107 VAL A CA 1 ATOM 686 C C . VAL A 1 107 ? -8.047 -1.106 -15.234 1.00 25.89 ? 107 VAL A C 1 ATOM 687 O O . VAL A 1 107 ? -8.279 -0.224 -16.068 1.00 29.31 ? 107 VAL A O 1 ATOM 688 C CB . VAL A 1 107 ? -5.754 -2.149 -14.944 1.00 25.81 ? 107 VAL A CB 1 ATOM 689 C CG1 . VAL A 1 107 ? -5.520 -1.969 -16.432 1.00 28.71 ? 107 VAL A CG1 1 ATOM 690 C CG2 . VAL A 1 107 ? -4.435 -2.065 -14.176 1.00 26.95 ? 107 VAL A CG2 1 ATOM 691 N N . ASN A 1 108 ? -8.902 -2.099 -15.016 1.00 23.08 ? 108 ASN A N 1 ATOM 692 C CA . ASN A 1 108 ? -10.141 -2.206 -15.769 1.00 24.43 ? 108 ASN A CA 1 ATOM 693 C C . ASN A 1 108 ? -11.110 -1.088 -15.380 1.00 27.59 ? 108 ASN A C 1 ATOM 694 O O . ASN A 1 108 ? -11.070 -0.545 -14.267 1.00 23.41 ? 108 ASN A O 1 ATOM 695 C CB . ASN A 1 108 ? -10.782 -3.582 -15.558 1.00 25.47 ? 108 ASN A CB 1 ATOM 696 C CG . ASN A 1 108 ? -11.219 -3.819 -14.126 1.00 25.38 ? 108 ASN A CG 1 ATOM 697 O OD1 . ASN A 1 108 ? -10.492 -3.519 -13.175 1.00 22.87 ? 108 ASN A OD1 1 ATOM 698 N ND2 . ASN A 1 108 ? -12.412 -4.369 -13.964 1.00 24.19 ? 108 ASN A ND2 1 ATOM 699 N N . ARG A 1 109 ? -11.988 -0.734 -16.328 1.00 23.39 ? 109 ARG A N 1 ATOM 700 C CA . ARG A 1 109 ? -12.871 0.410 -16.117 1.00 28.32 ? 109 ARG A CA 1 ATOM 701 C C . ARG A 1 109 ? -13.756 0.212 -14.888 1.00 29.95 ? 109 ARG A C 1 ATOM 702 O O . ARG A 1 109 ? -14.029 1.168 -14.149 1.00 23.93 ? 109 ARG A O 1 ATOM 703 C CB . ARG A 1 109 ? -13.716 0.665 -17.369 1.00 25.88 ? 109 ARG A CB 1 ATOM 704 C CG . ARG A 1 109 ? -14.563 1.908 -17.222 1.00 27.49 ? 109 ARG A CG 1 ATOM 705 C CD . ARG A 1 109 ? -15.254 2.323 -18.497 1.00 32.66 ? 109 ARG A CD 1 ATOM 706 N NE . ARG A 1 109 ? -16.021 3.532 -18.216 1.00 35.85 ? 109 ARG A NE 1 ATOM 707 C CZ . ARG A 1 109 ? -16.530 4.338 -19.136 1.00 37.69 ? 109 ARG A CZ 1 ATOM 708 N NH1 . ARG A 1 109 ? -16.346 4.073 -20.421 1.00 32.54 ? 109 ARG A NH1 1 ATOM 709 N NH2 . ARG A 1 109 ? -17.213 5.417 -18.762 1.00 31.95 ? 109 ARG A NH2 1 ATOM 710 N N . ASP A 1 110 ? -14.159 -1.037 -14.614 1.00 23.09 ? 110 ASP A N 1 ATOM 711 C CA . ASP A 1 110 ? -15.037 -1.292 -13.477 1.00 23.58 ? 110 ASP A CA 1 ATOM 712 C C . ASP A 1 110 ? -14.359 -1.030 -12.128 1.00 19.99 ? 110 ASP A C 1 ATOM 713 O O . ASP A 1 110 ? -15.056 -0.953 -11.113 1.00 20.17 ? 110 ASP A O 1 ATOM 714 C CB . ASP A 1 110 ? -15.570 -2.729 -13.515 1.00 23.82 ? 110 ASP A CB 1 ATOM 715 C CG . ASP A 1 110 ? -16.666 -2.929 -14.552 1.00 31.35 ? 110 ASP A CG 1 ATOM 716 O OD1 . ASP A 1 110 ? -17.326 -1.935 -14.945 1.00 32.79 ? 110 ASP A OD1 1 ATOM 717 O OD2 . ASP A 1 110 ? -16.870 -4.092 -14.960 1.00 32.12 ? 110 ASP A OD2 1 ATOM 718 N N A SER A 1 111 ? -13.027 -0.899 -12.093 0.50 21.44 ? 111 SER A N 1 ATOM 719 N N B SER A 1 111 ? -13.030 -0.882 -12.086 0.50 21.44 ? 111 SER A N 1 ATOM 720 C CA A SER A 1 111 ? -12.363 -0.489 -10.857 0.50 19.89 ? 111 SER A CA 1 ATOM 721 C CA B SER A 1 111 ? -12.397 -0.501 -10.824 0.50 19.88 ? 111 SER A CA 1 ATOM 722 C C A SER A 1 111 ? -12.848 0.873 -10.375 0.50 20.82 ? 111 SER A C 1 ATOM 723 C C B SER A 1 111 ? -12.738 0.926 -10.406 0.50 20.82 ? 111 SER A C 1 ATOM 724 O O A SER A 1 111 ? -12.746 1.173 -9.177 0.50 21.01 ? 111 SER A O 1 ATOM 725 O O B SER A 1 111 ? -12.408 1.325 -9.281 0.50 21.05 ? 111 SER A O 1 ATOM 726 C CB A SER A 1 111 ? -10.841 -0.456 -11.046 0.50 20.68 ? 111 SER A CB 1 ATOM 727 C CB B SER A 1 111 ? -10.878 -0.658 -10.911 0.50 20.93 ? 111 SER A CB 1 ATOM 728 O OG A SER A 1 111 ? -10.282 -1.761 -11.146 0.50 13.75 ? 111 SER A OG 1 ATOM 729 O OG B SER A 1 111 ? -10.326 0.239 -11.856 0.50 23.25 ? 111 SER A OG 1 ATOM 730 N N . LEU A 1 112 ? -13.375 1.701 -11.277 1.00 20.58 ? 112 LEU A N 1 ATOM 731 C CA . LEU A 1 112 ? -13.857 3.022 -10.924 1.00 20.27 ? 112 LEU A CA 1 ATOM 732 C C . LEU A 1 112 ? -15.219 2.991 -10.237 1.00 24.57 ? 112 LEU A C 1 ATOM 733 O O . LEU A 1 112 ? -15.701 4.051 -9.812 1.00 22.94 ? 112 LEU A O 1 ATOM 734 C CB . LEU A 1 112 ? -13.942 3.897 -12.189 1.00 24.82 ? 112 LEU A CB 1 ATOM 735 C CG . LEU A 1 112 ? -12.604 4.178 -12.875 1.00 23.93 ? 112 LEU A CG 1 ATOM 736 C CD1 . LEU A 1 112 ? -12.821 4.792 -14.266 1.00 28.35 ? 112 LEU A CD1 1 ATOM 737 C CD2 . LEU A 1 112 ? -11.764 5.100 -12.011 1.00 23.99 ? 112 LEU A CD2 1 ATOM 738 N N . MET A 1 113 ? -15.860 1.824 -10.146 1.00 20.67 ? 113 MET A N 1 ATOM 739 C CA . MET A 1 113 ? -17.181 1.747 -9.528 1.00 20.29 ? 113 MET A CA 1 ATOM 740 C C . MET A 1 113 ? -17.086 2.056 -8.041 1.00 22.20 ? 113 MET A C 1 ATOM 741 O O . MET A 1 113 ? -16.234 1.479 -7.344 1.00 20.61 ? 113 MET A O 1 ATOM 742 C CB . MET A 1 113 ? -17.795 0.365 -9.712 1.00 22.08 ? 113 MET A CB 1 ATOM 743 C CG . MET A 1 113 ? -18.165 0.013 -11.135 1.00 24.87 ? 113 MET A CG 1 ATOM 744 S SD . MET A 1 113 ? -18.696 -1.719 -11.245 1.00 39.39 ? 113 MET A SD 1 ATOM 745 C CE . MET A 1 113 ? -20.167 -1.665 -10.220 1.00 34.19 ? 113 MET A CE 1 ATOM 746 N N . PRO A 1 114 ? -17.937 2.944 -7.512 1.00 20.12 ? 114 PRO A N 1 ATOM 747 C CA . PRO A 1 114 ? -17.918 3.207 -6.064 1.00 22.08 ? 114 PRO A CA 1 ATOM 748 C C . PRO A 1 114 ? -18.200 1.974 -5.220 1.00 21.07 ? 114 PRO A C 1 ATOM 749 O O . PRO A 1 114 ? -17.913 2.006 -4.021 1.00 22.24 ? 114 PRO A O 1 ATOM 750 C CB . PRO A 1 114 ? -19.006 4.278 -5.891 1.00 24.90 ? 114 PRO A CB 1 ATOM 751 C CG . PRO A 1 114 ? -18.979 5.018 -7.213 1.00 23.71 ? 114 PRO A CG 1 ATOM 752 C CD . PRO A 1 114 ? -18.805 3.900 -8.229 1.00 22.47 ? 114 PRO A CD 1 ATOM 753 N N . LEU A 1 115 ? -18.742 0.902 -5.818 1.00 21.50 ? 115 LEU A N 1 ATOM 754 C CA . LEU A 1 115 ? -18.882 -0.395 -5.150 1.00 23.56 ? 115 LEU A CA 1 ATOM 755 C C . LEU A 1 115 ? -17.623 -0.787 -4.378 1.00 21.83 ? 115 LEU A C 1 ATOM 756 O O . LEU A 1 115 ? -17.705 -1.326 -3.264 1.00 21.77 ? 115 LEU A O 1 ATOM 757 C CB . LEU A 1 115 ? -19.197 -1.475 -6.194 1.00 24.70 ? 115 LEU A CB 1 ATOM 758 C CG . LEU A 1 115 ? -19.136 -2.939 -5.749 1.00 26.89 ? 115 LEU A CG 1 ATOM 759 C CD1 . LEU A 1 115 ? -20.350 -3.260 -4.888 1.00 34.33 ? 115 LEU A CD1 1 ATOM 760 C CD2 . LEU A 1 115 ? -19.032 -3.897 -6.930 1.00 29.10 ? 115 LEU A CD2 1 ATOM 761 N N . TRP A 1 116 ? -16.452 -0.533 -4.955 1.00 19.48 ? 116 TRP A N 1 ATOM 762 C CA . TRP A 1 116 ? -15.200 -1.010 -4.358 1.00 18.46 ? 116 TRP A CA 1 ATOM 763 C C . TRP A 1 116 ? -14.666 -0.066 -3.296 1.00 17.81 ? 116 TRP A C 1 ATOM 764 O O . TRP A 1 116 ? -13.803 -0.455 -2.498 1.00 19.52 ? 116 TRP A O 1 ATOM 765 C CB . TRP A 1 116 ? -14.129 -1.190 -5.446 1.00 15.69 ? 116 TRP A CB 1 ATOM 766 C CG . TRP A 1 116 ? -14.589 -2.000 -6.629 1.00 20.02 ? 116 TRP A CG 1 ATOM 767 C CD1 . TRP A 1 116 ? -14.820 -1.539 -7.906 1.00 21.12 ? 116 TRP A CD1 1 ATOM 768 C CD2 . TRP A 1 116 ? -14.881 -3.410 -6.653 1.00 20.73 ? 116 TRP A CD2 1 ATOM 769 N NE1 . TRP A 1 116 ? -15.232 -2.581 -8.714 1.00 20.89 ? 116 TRP A NE1 1 ATOM 770 C CE2 . TRP A 1 116 ? -15.279 -3.734 -7.972 1.00 19.65 ? 116 TRP A CE2 1 ATOM 771 C CE3 . TRP A 1 116 ? -14.848 -4.422 -5.689 1.00 20.10 ? 116 TRP A CE3 1 ATOM 772 C CZ2 . TRP A 1 116 ? -15.637 -5.031 -8.351 1.00 19.73 ? 116 TRP A CZ2 1 ATOM 773 C CZ3 . TRP A 1 116 ? -15.197 -5.718 -6.070 1.00 22.99 ? 116 TRP A CZ3 1 ATOM 774 C CH2 . TRP A 1 116 ? -15.584 -6.006 -7.394 1.00 19.86 ? 116 TRP A CH2 1 ATOM 775 N N . TRP A 1 117 ? -15.173 1.156 -3.260 1.00 18.60 ? 117 TRP A N 1 ATOM 776 C CA . TRP A 1 117 ? -14.572 2.249 -2.510 1.00 18.34 ? 117 TRP A CA 1 ATOM 777 C C . TRP A 1 117 ? -15.455 2.787 -1.405 1.00 19.04 ? 117 TRP A C 1 ATOM 778 O O . TRP A 1 117 ? -14.944 3.468 -0.514 1.00 20.23 ? 117 TRP A O 1 ATOM 779 C CB . TRP A 1 117 ? -14.217 3.402 -3.467 1.00 18.54 ? 117 TRP A CB 1 ATOM 780 C CG . TRP A 1 117 ? -13.236 3.008 -4.541 1.00 17.55 ? 117 TRP A CG 1 ATOM 781 C CD1 . TRP A 1 117 ? -13.525 2.474 -5.775 1.00 16.63 ? 117 TRP A CD1 1 ATOM 782 C CD2 . TRP A 1 117 ? -11.807 3.102 -4.467 1.00 20.01 ? 117 TRP A CD2 1 ATOM 783 N NE1 . TRP A 1 117 ? -12.363 2.245 -6.471 1.00 18.53 ? 117 TRP A NE1 1 ATOM 784 C CE2 . TRP A 1 117 ? -11.292 2.619 -5.689 1.00 17.16 ? 117 TRP A CE2 1 ATOM 785 C CE3 . TRP A 1 117 ? -10.912 3.568 -3.486 1.00 17.44 ? 117 TRP A CE3 1 ATOM 786 C CZ2 . TRP A 1 117 ? -9.923 2.583 -5.963 1.00 17.96 ? 117 TRP A CZ2 1 ATOM 787 C CZ3 . TRP A 1 117 ? -9.549 3.528 -3.757 1.00 19.87 ? 117 TRP A CZ3 1 ATOM 788 C CH2 . TRP A 1 117 ? -9.066 3.042 -4.989 1.00 16.78 ? 117 TRP A CH2 1 ATOM 789 N N . ASN A 1 118 ? -16.754 2.496 -1.418 1.00 21.06 ? 118 ASN A N 1 ATOM 790 C CA . ASN A 1 118 ? -17.665 3.128 -0.478 1.00 22.87 ? 118 ASN A CA 1 ATOM 791 C C . ASN A 1 118 ? -17.718 2.437 0.882 1.00 22.43 ? 118 ASN A C 1 ATOM 792 O O . ASN A 1 118 ? -18.531 2.825 1.729 1.00 22.50 ? 118 ASN A O 1 ATOM 793 C CB . ASN A 1 118 ? -19.066 3.221 -1.103 1.00 21.42 ? 118 ASN A CB 1 ATOM 794 C CG . ASN A 1 118 ? -19.201 4.414 -2.049 1.00 23.97 ? 118 ASN A CG 1 ATOM 795 O OD1 . ASN A 1 118 ? -18.245 5.156 -2.267 1.00 26.10 ? 118 ASN A OD1 1 ATOM 796 N ND2 . ASN A 1 118 ? -20.404 4.615 -2.602 1.00 27.94 ? 118 ASN A ND2 1 ATOM 797 N N . GLY A 1 119 ? -16.849 1.454 1.135 1.00 20.32 ? 119 GLY A N 1 ATOM 798 C CA . GLY A 1 119 ? -16.905 0.719 2.385 1.00 22.92 ? 119 GLY A CA 1 ATOM 799 C C . GLY A 1 119 ? -16.416 1.493 3.591 1.00 23.09 ? 119 GLY A C 1 ATOM 800 O O . GLY A 1 119 ? -16.670 1.071 4.722 1.00 24.33 ? 119 GLY A O 1 ATOM 801 N N . SER A 1 120 ? -15.685 2.583 3.374 1.00 18.79 ? 120 SER A N 1 ATOM 802 C CA . SER A 1 120 ? -15.333 3.533 4.423 1.00 19.59 ? 120 SER A CA 1 ATOM 803 C C . SER A 1 120 ? -14.891 4.819 3.741 1.00 20.59 ? 120 SER A C 1 ATOM 804 O O . SER A 1 120 ? -14.438 4.798 2.596 1.00 24.56 ? 120 SER A O 1 ATOM 805 C CB . SER A 1 120 ? -14.224 3.010 5.353 1.00 21.00 ? 120 SER A CB 1 ATOM 806 O OG . SER A 1 120 ? -14.701 2.034 6.287 1.00 20.84 ? 120 SER A OG 1 ATOM 807 N N . GLU A 1 121 ? -15.051 5.936 4.447 1.00 19.50 ? 121 GLU A N 1 ATOM 808 C CA . GLU A 1 121 ? -14.706 7.256 3.928 1.00 21.03 ? 121 GLU A CA 1 ATOM 809 C C . GLU A 1 121 ? -13.230 7.561 4.180 1.00 18.41 ? 121 GLU A C 1 ATOM 810 O O . GLU A 1 121 ? -12.822 7.648 5.345 1.00 20.36 ? 121 GLU A O 1 ATOM 811 C CB . GLU A 1 121 ? -15.568 8.304 4.603 1.00 21.46 ? 121 GLU A CB 1 ATOM 812 C CG . GLU A 1 121 ? -15.365 9.708 4.071 1.00 21.98 ? 121 GLU A CG 1 ATOM 813 C CD . GLU A 1 121 ? -16.447 10.668 4.567 1.00 30.24 ? 121 GLU A CD 1 ATOM 814 O OE1 . GLU A 1 121 ? -17.640 10.443 4.262 1.00 32.56 ? 121 GLU A OE1 1 ATOM 815 O OE2 . GLU A 1 121 ? -16.103 11.643 5.264 1.00 29.28 ? 121 GLU A OE2 1 ATOM 816 N N . PRO A 1 122 ? -12.402 7.735 3.155 1.00 18.36 ? 122 PRO A N 1 ATOM 817 C CA . PRO A 1 122 ? -10.988 8.045 3.398 1.00 18.58 ? 122 PRO A CA 1 ATOM 818 C C . PRO A 1 122 ? -10.799 9.529 3.706 1.00 22.49 ? 122 PRO A C 1 ATOM 819 O O . PRO A 1 122 ? -11.676 10.351 3.449 1.00 19.40 ? 122 PRO A O 1 ATOM 820 C CB . PRO A 1 122 ? -10.317 7.646 2.079 1.00 17.25 ? 122 PRO A CB 1 ATOM 821 C CG . PRO A 1 122 ? -11.388 8.007 1.035 1.00 18.05 ? 122 PRO A CG 1 ATOM 822 C CD . PRO A 1 122 ? -12.714 7.666 1.715 1.00 20.36 ? 122 PRO A CD 1 ATOM 823 N N . LEU A 1 123 ? -9.622 9.868 4.244 1.00 19.11 ? 123 LEU A N 1 ATOM 824 C CA . LEU A 1 123 ? -9.422 11.200 4.838 1.00 22.63 ? 123 LEU A CA 1 ATOM 825 C C . LEU A 1 123 ? -9.650 12.329 3.833 1.00 24.55 ? 123 LEU A C 1 ATOM 826 O O . LEU A 1 123 ? -10.213 13.386 4.182 1.00 22.65 ? 123 LEU A O 1 ATOM 827 C CB . LEU A 1 123 ? -8.014 11.297 5.443 1.00 20.51 ? 123 LEU A CB 1 ATOM 828 C CG . LEU A 1 123 ? -7.693 12.566 6.243 1.00 22.85 ? 123 LEU A CG 1 ATOM 829 C CD1 . LEU A 1 123 ? -8.687 12.729 7.396 1.00 24.18 ? 123 LEU A CD1 1 ATOM 830 C CD2 . LEU A 1 123 ? -6.261 12.543 6.777 1.00 23.30 ? 123 LEU A CD2 1 ATOM 831 N N . TRP A 1 124 ? -9.223 12.145 2.581 1.00 17.77 ? 124 TRP A N 1 ATOM 832 C CA . TRP A 1 124 ? -9.362 13.253 1.639 1.00 19.88 ? 124 TRP A CA 1 ATOM 833 C C . TRP A 1 124 ? -10.820 13.571 1.352 1.00 21.41 ? 124 TRP A C 1 ATOM 834 O O . TRP A 1 124 ? -11.149 14.731 1.070 1.00 22.54 ? 124 TRP A O 1 ATOM 835 C CB . TRP A 1 124 ? -8.600 12.981 0.333 1.00 18.95 ? 124 TRP A CB 1 ATOM 836 C CG . TRP A 1 124 ? -9.104 11.915 -0.606 1.00 21.76 ? 124 TRP A CG 1 ATOM 837 C CD1 . TRP A 1 124 ? -9.992 12.074 -1.634 1.00 17.64 ? 124 TRP A CD1 1 ATOM 838 C CD2 . TRP A 1 124 ? -8.649 10.559 -0.674 1.00 17.30 ? 124 TRP A CD2 1 ATOM 839 N NE1 . TRP A 1 124 ? -10.156 10.882 -2.306 1.00 18.91 ? 124 TRP A NE1 1 ATOM 840 C CE2 . TRP A 1 124 ? -9.333 9.940 -1.737 1.00 21.19 ? 124 TRP A CE2 1 ATOM 841 C CE3 . TRP A 1 124 ? -7.740 9.801 0.085 1.00 17.11 ? 124 TRP A CE3 1 ATOM 842 C CZ2 . TRP A 1 124 ? -9.146 8.590 -2.067 1.00 21.28 ? 124 TRP A CZ2 1 ATOM 843 C CZ3 . TRP A 1 124 ? -7.547 8.469 -0.243 1.00 20.10 ? 124 TRP A CZ3 1 ATOM 844 C CH2 . TRP A 1 124 ? -8.245 7.874 -1.319 1.00 22.79 ? 124 TRP A CH2 1 ATOM 845 N N . ILE A 1 125 ? -11.702 12.574 1.420 1.00 20.21 ? 125 ILE A N 1 ATOM 846 C CA . ILE A 1 125 ? -13.127 12.834 1.235 1.00 22.89 ? 125 ILE A CA 1 ATOM 847 C C . ILE A 1 125 ? -13.684 13.582 2.439 1.00 22.05 ? 125 ILE A C 1 ATOM 848 O O . ILE A 1 125 ? -14.449 14.547 2.298 1.00 23.67 ? 125 ILE A O 1 ATOM 849 C CB . ILE A 1 125 ? -13.881 11.511 0.989 1.00 23.12 ? 125 ILE A CB 1 ATOM 850 C CG1 . ILE A 1 125 ? -13.345 10.813 -0.271 1.00 21.52 ? 125 ILE A CG1 1 ATOM 851 C CG2 . ILE A 1 125 ? -15.393 11.745 0.927 1.00 21.87 ? 125 ILE A CG2 1 ATOM 852 C CD1 . ILE A 1 125 ? -13.567 11.581 -1.571 1.00 20.65 ? 125 ILE A CD1 1 ATOM 853 N N . THR A 1 126 ? -13.295 13.161 3.640 1.00 23.45 ? 126 THR A N 1 ATOM 854 C CA . THR A 1 126 ? -13.721 13.871 4.843 1.00 26.05 ? 126 THR A CA 1 ATOM 855 C C . THR A 1 126 ? -13.277 15.335 4.798 1.00 27.70 ? 126 THR A C 1 ATOM 856 O O . THR A 1 126 ? -14.048 16.237 5.153 1.00 28.88 ? 126 THR A O 1 ATOM 857 C CB . THR A 1 126 ? -13.161 13.164 6.081 1.00 25.58 ? 126 THR A CB 1 ATOM 858 O OG1 . THR A 1 126 ? -13.526 11.774 6.064 1.00 25.44 ? 126 THR A OG1 1 ATOM 859 C CG2 . THR A 1 126 ? -13.694 13.796 7.364 1.00 30.75 ? 126 THR A CG2 1 ATOM 860 N N . LEU A 1 127 ? -12.045 15.590 4.337 1.00 23.13 ? 127 LEU A N 1 ATOM 861 C CA . LEU A 1 127 ? -11.548 16.961 4.228 1.00 23.94 ? 127 LEU A CA 1 ATOM 862 C C . LEU A 1 127 ? -12.345 17.765 3.203 1.00 26.73 ? 127 LEU A C 1 ATOM 863 O O . LEU A 1 127 ? -12.723 18.914 3.469 1.00 23.65 ? 127 LEU A O 1 ATOM 864 C CB . LEU A 1 127 ? -10.057 16.949 3.875 1.00 26.39 ? 127 LEU A CB 1 ATOM 865 C CG . LEU A 1 127 ? -9.121 16.595 5.043 1.00 27.71 ? 127 LEU A CG 1 ATOM 866 C CD1 . LEU A 1 127 ? -7.777 16.138 4.538 1.00 30.50 ? 127 LEU A CD1 1 ATOM 867 C CD2 . LEU A 1 127 ? -8.947 17.787 5.993 1.00 30.86 ? 127 LEU A CD2 1 ATOM 868 N N . MET A 1 128 ? -12.607 17.184 2.025 1.00 22.89 ? 128 MET A N 1 ATOM 869 C CA . MET A 1 128 ? -13.449 17.861 1.037 1.00 25.13 ? 128 MET A CA 1 ATOM 870 C C . MET A 1 128 ? -14.821 18.195 1.609 1.00 29.58 ? 128 MET A C 1 ATOM 871 O O . MET A 1 128 ? -15.335 19.300 1.395 1.00 29.61 ? 128 MET A O 1 ATOM 872 C CB . MET A 1 128 ? -13.610 17.008 -0.224 1.00 25.32 ? 128 MET A CB 1 ATOM 873 C CG . MET A 1 128 ? -12.349 16.859 -1.065 1.00 23.88 ? 128 MET A CG 1 ATOM 874 S SD . MET A 1 128 ? -11.627 18.402 -1.664 1.00 25.82 ? 128 MET A SD 1 ATOM 875 C CE . MET A 1 128 ? -12.956 18.981 -2.729 1.00 24.83 ? 128 MET A CE 1 ATOM 876 N N . LYS A 1 129 ? -15.442 17.255 2.321 1.00 24.85 ? 129 LYS A N 1 ATOM 877 C CA . LYS A 1 129 ? -16.770 17.535 2.869 1.00 30.67 ? 129 LYS A CA 1 ATOM 878 C C . LYS A 1 129 ? -16.715 18.586 3.972 1.00 33.28 ? 129 LYS A C 1 ATOM 879 O O . LYS A 1 129 ? -17.726 19.242 4.250 1.00 34.28 ? 129 LYS A O 1 ATOM 880 C CB . LYS A 1 129 ? -17.418 16.243 3.366 1.00 30.99 ? 129 LYS A CB 1 ATOM 881 C CG . LYS A 1 129 ? -17.799 15.314 2.206 1.00 30.17 ? 129 LYS A CG 1 ATOM 882 C CD . LYS A 1 129 ? -17.970 13.856 2.629 1.00 27.96 ? 129 LYS A CD 1 ATOM 883 C CE . LYS A 1 129 ? -19.193 13.659 3.505 1.00 38.76 ? 129 LYS A CE 1 ATOM 884 N NZ . LYS A 1 129 ? -19.533 12.215 3.695 1.00 38.56 ? 129 LYS A NZ 1 ATOM 885 N N . ALA A 1 130 ? -15.558 18.777 4.598 1.00 25.47 ? 130 ALA A N 1 ATOM 886 C CA . ALA A 1 130 ? -15.386 19.871 5.546 1.00 32.61 ? 130 ALA A CA 1 ATOM 887 C C . ALA A 1 130 ? -14.947 21.161 4.866 1.00 34.61 ? 130 ALA A C 1 ATOM 888 O O . ALA A 1 130 ? -14.537 22.100 5.556 1.00 36.99 ? 130 ALA A O 1 ATOM 889 C CB . ALA A 1 130 ? -14.384 19.472 6.634 1.00 28.81 ? 130 ALA A CB 1 ATOM 890 N N . ARG A 1 131 ? -15.033 21.212 3.533 1.00 29.19 ? 131 ARG A N 1 ATOM 891 C CA . ARG A 1 131 ? -14.660 22.359 2.705 1.00 33.91 ? 131 ARG A CA 1 ATOM 892 C C . ARG A 1 131 ? -13.178 22.728 2.823 1.00 39.59 ? 131 ARG A C 1 ATOM 893 O O . ARG A 1 131 ? -12.807 23.891 2.652 1.00 37.19 ? 131 ARG A O 1 ATOM 894 C CB . ARG A 1 131 ? -15.559 23.568 3.001 1.00 43.49 ? 131 ARG A CB 1 ATOM 895 C CG . ARG A 1 131 ? -17.024 23.305 2.658 1.00 41.87 ? 131 ARG A CG 1 ATOM 896 C CD . ARG A 1 131 ? -17.938 24.466 3.052 1.00 59.71 ? 131 ARG A CD 1 ATOM 897 N NE . ARG A 1 131 ? -17.491 25.736 2.481 1.00 71.41 ? 131 ARG A NE 1 ATOM 898 C CZ . ARG A 1 131 ? -17.699 26.110 1.221 1.00 72.96 ? 131 ARG A CZ 1 ATOM 899 N NH1 . ARG A 1 131 ? -18.345 25.308 0.383 1.00 71.34 ? 131 ARG A NH1 1 ATOM 900 N NH2 . ARG A 1 131 ? -17.254 27.285 0.795 1.00 63.54 ? 131 ARG A NH2 1 ATOM 901 N N . ARG A 1 132 ? -12.314 21.751 3.089 1.00 27.52 ? 132 ARG A N 1 ATOM 902 C CA . ARG A 1 132 ? -10.877 21.922 2.915 1.00 26.05 ? 132 ARG A CA 1 ATOM 903 C C . ARG A 1 132 ? -10.506 21.514 1.490 1.00 28.30 ? 132 ARG A C 1 ATOM 904 O O . ARG A 1 132 ? -11.241 20.772 0.837 1.00 34.56 ? 132 ARG A O 1 ATOM 905 C CB . ARG A 1 132 ? -10.113 21.088 3.950 1.00 28.95 ? 132 ARG A CB 1 ATOM 906 C CG . ARG A 1 132 ? -10.580 21.346 5.388 1.00 35.50 ? 132 ARG A CG 1 ATOM 907 C CD . ARG A 1 132 ? -9.860 22.542 6.004 1.00 39.29 ? 132 ARG A CD 1 ATOM 908 N NE . ARG A 1 132 ? -8.438 22.233 6.075 1.00 53.48 ? 132 ARG A NE 1 ATOM 909 C CZ . ARG A 1 132 ? -7.871 21.559 7.071 1.00 52.96 ? 132 ARG A CZ 1 ATOM 910 N NH1 . ARG A 1 132 ? -8.608 21.154 8.101 1.00 47.95 ? 132 ARG A NH1 1 ATOM 911 N NH2 . ARG A 1 132 ? -6.567 21.292 7.041 1.00 43.29 ? 132 ARG A NH2 1 ATOM 912 N N . LYS A 1 133 ? -9.387 22.037 0.988 1.00 27.95 ? 133 LYS A N 1 ATOM 913 C CA . LYS A 1 133 ? -8.976 21.798 -0.396 1.00 24.34 ? 133 LYS A CA 1 ATOM 914 C C . LYS A 1 133 ? -7.892 20.725 -0.436 1.00 24.15 ? 133 LYS A C 1 ATOM 915 O O . LYS A 1 133 ? -6.937 20.783 0.344 1.00 22.84 ? 133 LYS A O 1 ATOM 916 C CB . LYS A 1 133 ? -8.461 23.083 -1.047 1.00 29.29 ? 133 LYS A CB 1 ATOM 917 C CG . LYS A 1 133 ? -9.426 24.287 -0.979 1.00 30.37 ? 133 LYS A CG 1 ATOM 918 C CD . LYS A 1 133 ? -8.621 25.587 -0.885 1.00 33.83 ? 133 LYS A CD 1 ATOM 919 C CE . LYS A 1 133 ? -9.473 26.832 -1.103 1.00 39.51 ? 133 LYS A CE 1 ATOM 920 N NZ . LYS A 1 133 ? -10.524 26.948 -0.070 1.00 48.63 ? 133 LYS A NZ 1 ATOM 921 N N . VAL A 1 134 ? -8.028 19.761 -1.352 1.00 22.83 ? 134 VAL A N 1 ATOM 922 C CA . VAL A 1 134 ? -7.122 18.606 -1.404 1.00 21.10 ? 134 VAL A CA 1 ATOM 923 C C . VAL A 1 134 ? -6.553 18.455 -2.815 1.00 21.20 ? 134 VAL A C 1 ATOM 924 O O . VAL A 1 134 ? -7.310 18.350 -3.790 1.00 22.63 ? 134 VAL A O 1 ATOM 925 C CB . VAL A 1 134 ? -7.822 17.302 -0.976 1.00 24.14 ? 134 VAL A CB 1 ATOM 926 C CG1 . VAL A 1 134 ? -6.811 16.179 -0.938 1.00 22.99 ? 134 VAL A CG1 1 ATOM 927 C CG2 . VAL A 1 134 ? -8.481 17.446 0.397 1.00 22.98 ? 134 VAL A CG2 1 ATOM 928 N N . TYR A 1 135 ? -5.225 18.424 -2.927 1.00 18.27 ? 135 TYR A N 1 ATOM 929 C CA . TYR A 1 135 ? -4.547 18.182 -4.198 1.00 17.75 ? 135 TYR A CA 1 ATOM 930 C C . TYR A 1 135 ? -3.872 16.825 -4.120 1.00 19.75 ? 135 TYR A C 1 ATOM 931 O O . TYR A 1 135 ? -3.128 16.577 -3.174 1.00 19.34 ? 135 TYR A O 1 ATOM 932 C CB . TYR A 1 135 ? -3.485 19.240 -4.481 1.00 19.52 ? 135 TYR A CB 1 ATOM 933 C CG . TYR A 1 135 ? -3.996 20.449 -5.241 1.00 22.32 ? 135 TYR A CG 1 ATOM 934 C CD1 . TYR A 1 135 ? -5.168 21.077 -4.860 1.00 23.74 ? 135 TYR A CD1 1 ATOM 935 C CD2 . TYR A 1 135 ? -3.289 20.958 -6.319 1.00 21.85 ? 135 TYR A CD2 1 ATOM 936 C CE1 . TYR A 1 135 ? -5.636 22.199 -5.545 1.00 25.42 ? 135 TYR A CE1 1 ATOM 937 C CE2 . TYR A 1 135 ? -3.747 22.086 -7.013 1.00 26.45 ? 135 TYR A CE2 1 ATOM 938 C CZ . TYR A 1 135 ? -4.922 22.690 -6.617 1.00 28.11 ? 135 TYR A CZ 1 ATOM 939 O OH . TYR A 1 135 ? -5.384 23.805 -7.296 1.00 31.51 ? 135 TYR A OH 1 ATOM 940 N N . MET A 1 136 ? -4.089 15.970 -5.119 1.00 22.02 ? 136 MET A N 1 ATOM 941 C CA . MET A 1 136 ? -3.520 14.624 -5.072 1.00 18.24 ? 136 MET A CA 1 ATOM 942 C C . MET A 1 136 ? -2.763 14.337 -6.365 1.00 16.49 ? 136 MET A C 1 ATOM 943 O O . MET A 1 136 ? -3.265 14.603 -7.461 1.00 20.15 ? 136 MET A O 1 ATOM 944 C CB . MET A 1 136 ? -4.617 13.565 -4.830 1.00 18.91 ? 136 MET A CB 1 ATOM 945 C CG . MET A 1 136 ? -5.510 13.875 -3.610 1.00 21.20 ? 136 MET A CG 1 ATOM 946 S SD . MET A 1 136 ? -6.674 12.580 -3.147 1.00 22.58 ? 136 MET A SD 1 ATOM 947 C CE . MET A 1 136 ? -5.548 11.410 -2.381 1.00 21.65 ? 136 MET A CE 1 ATOM 948 N N . TYR A 1 137 ? -1.562 13.768 -6.239 1.00 16.89 ? 137 TYR A N 1 ATOM 949 C CA . TYR A 1 137 ? -0.673 13.562 -7.380 1.00 18.14 ? 137 TYR A CA 1 ATOM 950 C C . TYR A 1 137 ? -0.387 12.076 -7.504 1.00 16.37 ? 137 TYR A C 1 ATOM 951 O O . TYR A 1 137 ? 0.336 11.527 -6.668 1.00 16.38 ? 137 TYR A O 1 ATOM 952 C CB . TYR A 1 137 ? 0.642 14.332 -7.206 1.00 17.04 ? 137 TYR A CB 1 ATOM 953 C CG . TYR A 1 137 ? 0.473 15.824 -7.100 1.00 18.28 ? 137 TYR A CG 1 ATOM 954 C CD1 . TYR A 1 137 ? 0.114 16.409 -5.900 1.00 19.77 ? 137 TYR A CD1 1 ATOM 955 C CD2 . TYR A 1 137 ? 0.682 16.644 -8.199 1.00 21.70 ? 137 TYR A CD2 1 ATOM 956 C CE1 . TYR A 1 137 ? -0.036 17.800 -5.797 1.00 20.80 ? 137 TYR A CE1 1 ATOM 957 C CE2 . TYR A 1 137 ? 0.542 18.015 -8.106 1.00 23.72 ? 137 TYR A CE2 1 ATOM 958 C CZ . TYR A 1 137 ? 0.186 18.585 -6.903 1.00 23.79 ? 137 TYR A CZ 1 ATOM 959 O OH . TYR A 1 137 ? 0.041 19.956 -6.811 1.00 22.43 ? 137 TYR A OH 1 ATOM 960 N N . TYR A 1 138 ? -0.932 11.444 -8.551 1.00 18.60 ? 138 TYR A N 1 ATOM 961 C CA . TYR A 1 138 ? -0.751 10.032 -8.894 1.00 19.45 ? 138 TYR A CA 1 ATOM 962 C C . TYR A 1 138 ? -1.286 9.083 -7.823 1.00 20.13 ? 138 TYR A C 1 ATOM 963 O O . TYR A 1 138 ? -0.935 7.895 -7.824 1.00 17.79 ? 138 TYR A O 1 ATOM 964 C CB . TYR A 1 138 ? 0.732 9.687 -9.165 1.00 18.78 ? 138 TYR A CB 1 ATOM 965 C CG . TYR A 1 138 ? 1.449 10.654 -10.091 1.00 21.69 ? 138 TYR A CG 1 ATOM 966 C CD1 . TYR A 1 138 ? 1.028 10.825 -11.407 1.00 24.30 ? 138 TYR A CD1 1 ATOM 967 C CD2 . TYR A 1 138 ? 2.550 11.385 -9.655 1.00 20.60 ? 138 TYR A CD2 1 ATOM 968 C CE1 . TYR A 1 138 ? 1.672 11.699 -12.262 1.00 23.34 ? 138 TYR A CE1 1 ATOM 969 C CE2 . TYR A 1 138 ? 3.206 12.275 -10.510 1.00 23.15 ? 138 TYR A CE2 1 ATOM 970 C CZ . TYR A 1 138 ? 2.749 12.430 -11.813 1.00 26.88 ? 138 TYR A CZ 1 ATOM 971 O OH . TYR A 1 138 ? 3.375 13.304 -12.677 1.00 26.69 ? 138 TYR A OH 1 ATOM 972 N N . TRP A 1 139 ? -2.091 9.579 -6.897 1.00 18.16 ? 139 TRP A N 1 ATOM 973 C CA . TRP A 1 139 ? -2.518 8.785 -5.752 1.00 16.78 ? 139 TRP A CA 1 ATOM 974 C C . TRP A 1 139 ? -3.608 7.810 -6.168 1.00 15.38 ? 139 TRP A C 1 ATOM 975 O O . TRP A 1 139 ? -4.699 8.250 -6.560 1.00 18.29 ? 139 TRP A O 1 ATOM 976 C CB . TRP A 1 139 ? -3.048 9.690 -4.658 1.00 20.12 ? 139 TRP A CB 1 ATOM 977 C CG . TRP A 1 139 ? -3.181 9.036 -3.317 1.00 24.92 ? 139 TRP A CG 1 ATOM 978 C CD1 . TRP A 1 139 ? -4.204 8.236 -2.881 1.00 18.60 ? 139 TRP A CD1 1 ATOM 979 C CD2 . TRP A 1 139 ? -2.276 9.170 -2.215 1.00 18.12 ? 139 TRP A CD2 1 ATOM 980 N NE1 . TRP A 1 139 ? -3.974 7.857 -1.572 1.00 20.94 ? 139 TRP A NE1 1 ATOM 981 C CE2 . TRP A 1 139 ? -2.798 8.415 -1.146 1.00 19.74 ? 139 TRP A CE2 1 ATOM 982 C CE3 . TRP A 1 139 ? -1.068 9.853 -2.032 1.00 20.50 ? 139 TRP A CE3 1 ATOM 983 C CZ2 . TRP A 1 139 ? -2.165 8.341 0.098 1.00 19.55 ? 139 TRP A CZ2 1 ATOM 984 C CZ3 . TRP A 1 139 ? -0.443 9.774 -0.808 1.00 18.77 ? 139 TRP A CZ3 1 ATOM 985 C CH2 . TRP A 1 139 ? -0.993 9.027 0.245 1.00 19.67 ? 139 TRP A CH2 1 ATOM 986 N N . PRO A 1 140 ? -3.371 6.503 -6.089 1.00 18.85 ? 140 PRO A N 1 ATOM 987 C CA . PRO A 1 140 ? -4.370 5.525 -6.541 1.00 20.41 ? 140 PRO A CA 1 ATOM 988 C C . PRO A 1 140 ? -5.637 5.646 -5.713 1.00 18.00 ? 140 PRO A C 1 ATOM 989 O O . PRO A 1 140 ? -5.617 5.499 -4.492 1.00 20.21 ? 140 PRO A O 1 ATOM 990 C CB . PRO A 1 140 ? -3.656 4.179 -6.336 1.00 24.10 ? 140 PRO A CB 1 ATOM 991 C CG . PRO A 1 140 ? -2.190 4.538 -6.419 1.00 21.83 ? 140 PRO A CG 1 ATOM 992 C CD . PRO A 1 140 ? -2.102 5.857 -5.699 1.00 19.67 ? 140 PRO A CD 1 ATOM 993 N N . GLY A 1 141 ? -6.732 6.000 -6.386 1.00 18.38 ? 141 GLY A N 1 ATOM 994 C CA . GLY A 1 141 ? -7.997 6.301 -5.743 1.00 19.48 ? 141 GLY A CA 1 ATOM 995 C C . GLY A 1 141 ? -8.464 7.735 -5.919 1.00 21.26 ? 141 GLY A C 1 ATOM 996 O O . GLY A 1 141 ? -9.670 8.002 -5.772 1.00 20.00 ? 141 GLY A O 1 ATOM 997 N N . CYS A 1 142 ? -7.561 8.674 -6.233 1.00 18.62 ? 142 CYS A N 1 ATOM 998 C CA . CYS A 1 142 ? -8.000 10.067 -6.357 1.00 20.46 ? 142 CYS A CA 1 ATOM 999 C C . CYS A 1 142 ? -8.889 10.275 -7.569 1.00 21.59 ? 142 CYS A C 1 ATOM 1000 O O . CYS A 1 142 ? -9.615 11.282 -7.636 1.00 22.21 ? 142 CYS A O 1 ATOM 1001 C CB . CYS A 1 142 ? -6.796 11.030 -6.393 1.00 21.67 ? 142 CYS A CB 1 ATOM 1002 S SG . CYS A 1 142 ? -5.715 11.087 -7.849 1.00 25.43 ? 142 CYS A SG 1 ATOM 1003 N N . GLU A 1 143 ? -8.847 9.349 -8.526 1.00 19.91 ? 143 GLU A N 1 ATOM 1004 C CA . GLU A 1 143 ? -9.619 9.439 -9.756 1.00 26.01 ? 143 GLU A CA 1 ATOM 1005 C C . GLU A 1 143 ? -11.042 8.914 -9.608 1.00 26.68 ? 143 GLU A C 1 ATOM 1006 O O . GLU A 1 143 ? -11.792 8.932 -10.589 1.00 23.16 ? 143 GLU A O 1 ATOM 1007 C CB . GLU A 1 143 ? -8.894 8.667 -10.868 1.00 22.41 ? 143 GLU A CB 1 ATOM 1008 C CG . GLU A 1 143 ? -9.057 7.141 -10.796 1.00 24.36 ? 143 GLU A CG 1 ATOM 1009 C CD . GLU A 1 143 ? -8.151 6.429 -9.779 1.00 29.53 ? 143 GLU A CD 1 ATOM 1010 O OE1 . GLU A 1 143 ? -7.426 7.085 -9.012 1.00 25.39 ? 143 GLU A OE1 1 ATOM 1011 O OE2 . GLU A 1 143 ? -8.183 5.179 -9.743 1.00 31.71 ? 143 GLU A OE2 1 ATOM 1012 N N . VAL A 1 144 ? -11.432 8.458 -8.416 1.00 19.57 ? 144 VAL A N 1 ATOM 1013 C CA . VAL A 1 144 ? -12.721 7.811 -8.186 1.00 18.40 ? 144 VAL A CA 1 ATOM 1014 C C . VAL A 1 144 ? -13.665 8.809 -7.534 1.00 19.38 ? 144 VAL A C 1 ATOM 1015 O O . VAL A 1 144 ? -13.245 9.611 -6.697 1.00 19.98 ? 144 VAL A O 1 ATOM 1016 C CB . VAL A 1 144 ? -12.539 6.563 -7.293 1.00 23.11 ? 144 VAL A CB 1 ATOM 1017 C CG1 . VAL A 1 144 ? -13.868 5.842 -7.101 1.00 20.80 ? 144 VAL A CG1 1 ATOM 1018 C CG2 . VAL A 1 144 ? -11.510 5.642 -7.929 1.00 19.61 ? 144 VAL A CG2 1 ATOM 1019 N N . GLU A 1 145 ? -14.947 8.765 -7.915 1.00 22.52 ? 145 GLU A N 1 ATOM 1020 C CA . GLU A 1 145 ? -15.971 9.427 -7.111 1.00 23.26 ? 145 GLU A CA 1 ATOM 1021 C C . GLU A 1 145 ? -16.315 8.532 -5.924 1.00 21.87 ? 145 GLU A C 1 ATOM 1022 O O . GLU A 1 145 ? -16.966 7.493 -6.085 1.00 23.14 ? 145 GLU A O 1 ATOM 1023 C CB . GLU A 1 145 ? -17.218 9.723 -7.936 1.00 23.20 ? 145 GLU A CB 1 ATOM 1024 C CG . GLU A 1 145 ? -18.191 10.642 -7.195 1.00 27.28 ? 145 GLU A CG 1 ATOM 1025 C CD . GLU A 1 145 ? -19.553 10.715 -7.863 1.00 33.29 ? 145 GLU A CD 1 ATOM 1026 O OE1 . GLU A 1 145 ? -19.731 11.566 -8.757 1.00 36.88 ? 145 GLU A OE1 1 ATOM 1027 O OE2 . GLU A 1 145 ? -20.435 9.899 -7.508 1.00 31.54 ? 145 GLU A OE2 1 ATOM 1028 N N . ILE A 1 146 ? -15.898 8.935 -4.730 1.00 18.63 ? 146 ILE A N 1 ATOM 1029 C CA . ILE A 1 146 ? -16.058 8.118 -3.533 1.00 21.69 ? 146 ILE A CA 1 ATOM 1030 C C . ILE A 1 146 ? -17.108 8.775 -2.662 1.00 20.50 ? 146 ILE A C 1 ATOM 1031 O O . ILE A 1 146 ? -16.916 9.912 -2.206 1.00 22.35 ? 146 ILE A O 1 ATOM 1032 C CB . ILE A 1 146 ? -14.740 7.960 -2.767 1.00 20.93 ? 146 ILE A CB 1 ATOM 1033 C CG1 . ILE A 1 146 ? -13.675 7.303 -3.661 1.00 18.40 ? 146 ILE A CG1 1 ATOM 1034 C CG2 . ILE A 1 146 ? -14.999 7.197 -1.466 1.00 21.42 ? 146 ILE A CG2 1 ATOM 1035 C CD1 . ILE A 1 146 ? -12.255 7.214 -3.017 1.00 17.52 ? 146 ILE A CD1 1 ATOM 1036 N N . LEU A 1 147 ? -18.214 8.062 -2.435 1.00 20.63 ? 147 LEU A N 1 ATOM 1037 C CA . LEU A 1 147 ? -19.310 8.549 -1.593 1.00 21.72 ? 147 LEU A CA 1 ATOM 1038 C C . LEU A 1 147 ? -19.855 9.876 -2.121 1.00 25.52 ? 147 LEU A C 1 ATOM 1039 O O . LEU A 1 147 ? -20.245 10.758 -1.348 1.00 24.42 ? 147 LEU A O 1 ATOM 1040 C CB . LEU A 1 147 ? -18.865 8.689 -0.136 1.00 21.10 ? 147 LEU A CB 1 ATOM 1041 C CG . LEU A 1 147 ? -18.473 7.353 0.516 1.00 20.78 ? 147 LEU A CG 1 ATOM 1042 C CD1 . LEU A 1 147 ? -17.600 7.525 1.769 1.00 25.25 ? 147 LEU A CD1 1 ATOM 1043 C CD2 . LEU A 1 147 ? -19.715 6.537 0.838 1.00 23.76 ? 147 LEU A CD2 1 ATOM 1044 N N . GLY A 1 148 ? -19.826 10.029 -3.443 1.00 23.37 ? 148 GLY A N 1 ATOM 1045 C CA . GLY A 1 148 ? -20.318 11.210 -4.128 1.00 26.26 ? 148 GLY A CA 1 ATOM 1046 C C . GLY A 1 148 ? -19.348 12.367 -4.222 1.00 31.93 ? 148 GLY A C 1 ATOM 1047 O O . GLY A 1 148 ? -19.739 13.438 -4.718 1.00 25.79 ? 148 GLY A O 1 ATOM 1048 N N . VAL A 1 149 ? -18.094 12.189 -3.795 1.00 23.26 ? 149 VAL A N 1 ATOM 1049 C CA . VAL A 1 149 ? -17.147 13.284 -3.616 1.00 25.54 ? 149 VAL A CA 1 ATOM 1050 C C . VAL A 1 149 ? -15.844 12.965 -4.348 1.00 24.56 ? 149 VAL A C 1 ATOM 1051 O O . VAL A 1 149 ? -15.493 11.799 -4.537 1.00 21.02 ? 149 VAL A O 1 ATOM 1052 C CB . VAL A 1 149 ? -16.914 13.535 -2.102 1.00 24.11 ? 149 VAL A CB 1 ATOM 1053 C CG1 . VAL A 1 149 ? -15.833 14.583 -1.838 1.00 23.80 ? 149 VAL A CG1 1 ATOM 1054 C CG2 . VAL A 1 149 ? -18.220 13.932 -1.433 1.00 24.38 ? 149 VAL A CG2 1 ATOM 1055 N N . ARG A 1 150 ? -15.153 14.009 -4.801 1.00 24.09 ? 150 ARG A N 1 ATOM 1056 C CA . ARG A 1 150 ? -13.830 13.943 -5.405 1.00 23.15 ? 150 ARG A CA 1 ATOM 1057 C C . ARG A 1 150 ? -12.949 15.024 -4.808 1.00 25.95 ? 150 ARG A C 1 ATOM 1058 O O . ARG A 1 150 ? -13.449 16.048 -4.329 1.00 25.53 ? 150 ARG A O 1 ATOM 1059 C CB . ARG A 1 150 ? -13.887 14.130 -6.929 1.00 22.65 ? 150 ARG A CB 1 ATOM 1060 C CG . ARG A 1 150 ? -14.790 13.147 -7.682 1.00 20.47 ? 150 ARG A CG 1 ATOM 1061 C CD . ARG A 1 150 ? -14.791 13.462 -9.160 1.00 24.35 ? 150 ARG A CD 1 ATOM 1062 N NE . ARG A 1 150 ? -15.509 12.455 -9.948 1.00 24.99 ? 150 ARG A NE 1 ATOM 1063 C CZ . ARG A 1 150 ? -14.930 11.376 -10.461 1.00 23.80 ? 150 ARG A CZ 1 ATOM 1064 N NH1 . ARG A 1 150 ? -13.637 11.184 -10.275 1.00 23.97 ? 150 ARG A NH1 1 ATOM 1065 N NH2 . ARG A 1 150 ? -15.630 10.497 -11.162 1.00 23.60 ? 150 ARG A NH2 1 ATOM 1066 N N . PRO A 1 151 ? -11.623 14.844 -4.829 1.00 21.95 ? 151 PRO A N 1 ATOM 1067 C CA . PRO A 1 151 ? -10.719 15.908 -4.365 1.00 23.39 ? 151 PRO A CA 1 ATOM 1068 C C . PRO A 1 151 ? -10.694 17.102 -5.316 1.00 21.27 ? 151 PRO A C 1 ATOM 1069 O O . PRO A 1 151 ? -11.054 17.012 -6.495 1.00 22.98 ? 151 PRO A O 1 ATOM 1070 C CB . PRO A 1 151 ? -9.350 15.221 -4.325 1.00 22.61 ? 151 PRO A CB 1 ATOM 1071 C CG . PRO A 1 151 ? -9.455 14.144 -5.406 1.00 21.20 ? 151 PRO A CG 1 ATOM 1072 C CD . PRO A 1 151 ? -10.888 13.648 -5.294 1.00 22.15 ? 151 PRO A CD 1 ATOM 1073 N N . THR A 1 152 ? -10.242 18.238 -4.771 1.00 21.47 ? 152 THR A N 1 ATOM 1074 C CA . THR A 1 152 ? -10.132 19.472 -5.551 1.00 25.70 ? 152 THR A CA 1 ATOM 1075 C C . THR A 1 152 ? -9.339 19.251 -6.830 1.00 26.48 ? 152 THR A C 1 ATOM 1076 O O . THR A 1 152 ? -9.709 19.742 -7.904 1.00 22.62 ? 152 THR A O 1 ATOM 1077 C CB . THR A 1 152 ? -9.453 20.567 -4.715 1.00 23.49 ? 152 THR A CB 1 ATOM 1078 O OG1 . THR A 1 152 ? -10.124 20.726 -3.462 1.00 25.67 ? 152 THR A OG1 1 ATOM 1079 C CG2 . THR A 1 152 ? -9.457 21.907 -5.466 1.00 26.17 ? 152 THR A CG2 1 ATOM 1080 N N . TYR A 1 153 ? -8.249 18.492 -6.740 1.00 22.68 ? 153 TYR A N 1 ATOM 1081 C CA . TYR A 1 153 ? -7.368 18.273 -7.875 1.00 20.23 ? 153 TYR A CA 1 ATOM 1082 C C . TYR A 1 153 ? -6.814 16.863 -7.787 1.00 22.29 ? 153 TYR A C 1 ATOM 1083 O O . TYR A 1 153 ? -6.426 16.423 -6.705 1.00 22.80 ? 153 TYR A O 1 ATOM 1084 C CB . TYR A 1 153 ? -6.201 19.277 -7.876 1.00 21.20 ? 153 TYR A CB 1 ATOM 1085 C CG . TYR A 1 153 ? -5.162 19.001 -8.938 1.00 23.89 ? 153 TYR A CG 1 ATOM 1086 C CD1 . TYR A 1 153 ? -5.380 19.372 -10.250 1.00 29.24 ? 153 TYR A CD1 1 ATOM 1087 C CD2 . TYR A 1 153 ? -3.963 18.370 -8.622 1.00 23.34 ? 153 TYR A CD2 1 ATOM 1088 C CE1 . TYR A 1 153 ? -4.432 19.123 -11.234 1.00 30.21 ? 153 TYR A CE1 1 ATOM 1089 C CE2 . TYR A 1 153 ? -3.014 18.129 -9.587 1.00 23.93 ? 153 TYR A CE2 1 ATOM 1090 C CZ . TYR A 1 153 ? -3.253 18.507 -10.892 1.00 26.25 ? 153 TYR A CZ 1 ATOM 1091 O OH . TYR A 1 153 ? -2.306 18.261 -11.856 1.00 29.43 ? 153 TYR A OH 1 ATOM 1092 N N . CYS A 1 154 ? -6.802 16.157 -8.912 1.00 22.65 ? 154 CYS A N 1 ATOM 1093 C CA . CYS A 1 154 ? -6.231 14.812 -8.980 1.00 24.93 ? 154 CYS A CA 1 ATOM 1094 C C . CYS A 1 154 ? -5.462 14.708 -10.286 1.00 24.01 ? 154 CYS A C 1 ATOM 1095 O O . CYS A 1 154 ? -6.031 14.911 -11.365 1.00 26.73 ? 154 CYS A O 1 ATOM 1096 C CB . CYS A 1 154 ? -7.313 13.726 -8.878 1.00 23.84 ? 154 CYS A CB 1 ATOM 1097 S SG . CYS A 1 154 ? -6.836 11.972 -9.368 1.00 31.93 ? 154 CYS A SG 1 ATOM 1098 N N . LEU A 1 155 ? -4.160 14.453 -10.178 1.00 22.02 ? 155 LEU A N 1 ATOM 1099 C CA . LEU A 1 155 ? -3.335 14.088 -11.319 1.00 22.11 ? 155 LEU A CA 1 ATOM 1100 C C . LEU A 1 155 ? -3.354 12.565 -11.349 1.00 24.74 ? 155 LEU A C 1 ATOM 1101 O O . LEU A 1 155 ? -2.723 11.917 -10.512 1.00 22.48 ? 155 LEU A O 1 ATOM 1102 C CB . LEU A 1 155 ? -1.930 14.659 -11.168 1.00 22.01 ? 155 LEU A CB 1 ATOM 1103 C CG . LEU A 1 155 ? -0.886 14.314 -12.230 1.00 26.28 ? 155 LEU A CG 1 ATOM 1104 C CD1 . LEU A 1 155 ? -1.352 14.796 -13.600 1.00 28.94 ? 155 LEU A CD1 1 ATOM 1105 C CD2 . LEU A 1 155 ? 0.453 14.937 -11.848 1.00 25.06 ? 155 LEU A CD2 1 ATOM 1106 N N . GLU A 1 156 ? -4.132 11.994 -12.270 1.00 22.06 ? 156 GLU A N 1 ATOM 1107 C CA . GLU A 1 156 ? -4.442 10.568 -12.217 1.00 23.19 ? 156 GLU A CA 1 ATOM 1108 C C . GLU A 1 156 ? -3.203 9.714 -12.461 1.00 26.40 ? 156 GLU A C 1 ATOM 1109 O O . GLU A 1 156 ? -2.377 10.020 -13.324 1.00 26.44 ? 156 GLU A O 1 ATOM 1110 C CB . GLU A 1 156 ? -5.506 10.220 -13.260 1.00 32.06 ? 156 GLU A CB 1 ATOM 1111 C CG . GLU A 1 156 ? -6.016 8.785 -13.186 1.00 38.46 ? 156 GLU A CG 1 ATOM 1112 C CD . GLU A 1 156 ? -7.138 8.513 -14.186 1.00 39.65 ? 156 GLU A CD 1 ATOM 1113 O OE1 . GLU A 1 156 ? -7.433 9.411 -14.995 1.00 45.02 ? 156 GLU A OE1 1 ATOM 1114 O OE2 . GLU A 1 156 ? -7.723 7.406 -14.159 1.00 45.55 ? 156 GLU A OE2 1 ATOM 1115 N N . TYR A 1 157 ? -3.089 8.617 -11.708 1.00 20.54 ? 157 TYR A N 1 ATOM 1116 C CA . TYR A 1 157 ? -2.083 7.611 -12.013 1.00 25.66 ? 157 TYR A CA 1 ATOM 1117 C C . TYR A 1 157 ? -2.404 6.960 -13.353 1.00 27.06 ? 157 TYR A C 1 ATOM 1118 O O . TYR A 1 157 ? -3.518 6.479 -13.565 1.00 25.55 ? 157 TYR A O 1 ATOM 1119 C CB . TYR A 1 157 ? -2.042 6.547 -10.914 1.00 21.40 ? 157 TYR A CB 1 ATOM 1120 C CG . TYR A 1 157 ? -1.067 5.415 -11.161 1.00 21.56 ? 157 TYR A CG 1 ATOM 1121 C CD1 . TYR A 1 157 ? -1.379 4.379 -12.039 1.00 31.31 ? 157 TYR A CD1 1 ATOM 1122 C CD2 . TYR A 1 157 ? 0.153 5.368 -10.503 1.00 21.20 ? 157 TYR A CD2 1 ATOM 1123 C CE1 . TYR A 1 157 ? -0.503 3.346 -12.271 1.00 26.98 ? 157 TYR A CE1 1 ATOM 1124 C CE2 . TYR A 1 157 ? 1.045 4.316 -10.725 1.00 23.55 ? 157 TYR A CE2 1 ATOM 1125 C CZ . TYR A 1 157 ? 0.700 3.314 -11.621 1.00 24.60 ? 157 TYR A CZ 1 ATOM 1126 O OH . TYR A 1 157 ? 1.553 2.268 -11.874 1.00 23.50 ? 157 TYR A OH 1 ATOM 1127 N N . LYS A 1 158 ? -1.416 6.925 -14.248 1.00 26.50 ? 158 LYS A N 1 ATOM 1128 C CA . LYS A 1 158 ? -1.550 6.201 -15.511 1.00 36.33 ? 158 LYS A CA 1 ATOM 1129 C C . LYS A 1 158 ? -0.468 5.140 -15.638 1.00 33.75 ? 158 LYS A C 1 ATOM 1130 O O . LYS A 1 158 ? -0.779 3.947 -15.662 1.00 34.90 ? 158 LYS A O 1 ATOM 1131 C CB . LYS A 1 158 ? -1.516 7.189 -16.676 1.00 36.32 ? 158 LYS A CB 1 ATOM 1132 C CG . LYS A 1 158 ? -2.832 7.898 -16.851 1.00 41.85 ? 158 LYS A CG 1 ATOM 1133 C CD . LYS A 1 158 ? -2.653 9.281 -17.430 1.00 47.54 ? 158 LYS A CD 1 ATOM 1134 C CE . LYS A 1 158 ? -3.976 10.028 -17.410 1.00 49.20 ? 158 LYS A CE 1 ATOM 1135 N NZ . LYS A 1 158 ? -3.791 11.472 -17.698 1.00 53.49 ? 158 LYS A NZ 1 ATOM 1136 N N . THR A 1 159 ? 0.788 5.538 -15.719 1.00 31.15 ? 159 THR A N 1 ATOM 1137 C CA . THR A 1 159 ? 1.922 4.639 -15.748 1.00 29.18 ? 159 THR A CA 1 ATOM 1138 C C . THR A 1 159 ? 2.726 4.841 -14.478 1.00 26.92 ? 159 THR A C 1 ATOM 1139 O O . THR A 1 159 ? 2.397 5.683 -13.641 1.00 26.41 ? 159 THR A O 1 ATOM 1140 C CB . THR A 1 159 ? 2.784 4.895 -16.987 1.00 33.28 ? 159 THR A CB 1 ATOM 1141 O OG1 . THR A 1 159 ? 3.022 6.303 -17.117 1.00 33.58 ? 159 THR A OG1 1 ATOM 1142 C CG2 . THR A 1 159 ? 2.064 4.415 -18.229 1.00 35.83 ? 159 THR A CG2 1 ATOM 1143 N N . VAL A 1 160 ? 3.778 4.043 -14.328 1.00 23.61 ? 160 VAL A N 1 ATOM 1144 C CA . VAL A 1 160 ? 4.681 4.230 -13.200 1.00 24.62 ? 160 VAL A CA 1 ATOM 1145 C C . VAL A 1 160 ? 5.236 5.646 -13.307 1.00 30.23 ? 160 VAL A C 1 ATOM 1146 O O . VAL A 1 160 ? 5.804 6.007 -14.352 1.00 25.61 ? 160 VAL A O 1 ATOM 1147 C CB . VAL A 1 160 ? 5.802 3.182 -13.201 1.00 23.71 ? 160 VAL A CB 1 ATOM 1148 C CG1 . VAL A 1 160 ? 6.781 3.446 -12.081 1.00 28.31 ? 160 VAL A CG1 1 ATOM 1149 C CG2 . VAL A 1 160 ? 5.214 1.791 -13.085 1.00 30.70 ? 160 VAL A CG2 1 ATOM 1150 N N . PRO A 1 161 ? 5.056 6.494 -12.293 1.00 23.04 ? 161 PRO A N 1 ATOM 1151 C CA . PRO A 1 161 ? 5.654 7.831 -12.350 1.00 21.84 ? 161 PRO A CA 1 ATOM 1152 C C . PRO A 1 161 ? 7.175 7.737 -12.364 1.00 23.01 ? 161 PRO A C 1 ATOM 1153 O O . PRO A 1 161 ? 7.768 6.862 -11.728 1.00 24.04 ? 161 PRO A O 1 ATOM 1154 C CB . PRO A 1 161 ? 5.135 8.512 -11.073 1.00 22.52 ? 161 PRO A CB 1 ATOM 1155 C CG . PRO A 1 161 ? 3.858 7.795 -10.743 1.00 22.57 ? 161 PRO A CG 1 ATOM 1156 C CD . PRO A 1 161 ? 4.144 6.345 -11.146 1.00 22.92 ? 161 PRO A CD 1 ATOM 1157 N N . THR A 1 162 ? 7.803 8.646 -13.108 1.00 21.92 ? 162 THR A N 1 ATOM 1158 C CA . THR A 1 162 ? 9.255 8.744 -13.163 1.00 26.17 ? 162 THR A CA 1 ATOM 1159 C C . THR A 1 162 ? 9.767 9.562 -11.980 1.00 22.00 ? 162 THR A C 1 ATOM 1160 O O . THR A 1 162 ? 8.998 10.216 -11.271 1.00 21.45 ? 162 THR A O 1 ATOM 1161 C CB . THR A 1 162 ? 9.707 9.405 -14.471 1.00 27.50 ? 162 THR A CB 1 ATOM 1162 O OG1 . THR A 1 162 ? 9.286 10.773 -14.474 1.00 20.61 ? 162 THR A OG1 1 ATOM 1163 C CG2 . THR A 1 162 ? 9.102 8.700 -15.688 1.00 26.51 ? 162 THR A CG2 1 ATOM 1164 N N . ASP A 1 163 ? 11.089 9.542 -11.773 1.00 23.83 ? 163 ASP A N 1 ATOM 1165 C CA . ASP A 1 163 ? 11.677 10.393 -10.733 1.00 24.04 ? 163 ASP A CA 1 ATOM 1166 C C . ASP A 1 163 ? 11.498 11.878 -11.048 1.00 26.71 ? 163 ASP A C 1 ATOM 1167 O O . ASP A 1 163 ? 11.420 12.711 -10.133 1.00 22.78 ? 163 ASP A O 1 ATOM 1168 C CB . ASP A 1 163 ? 13.166 10.085 -10.568 1.00 24.14 ? 163 ASP A CB 1 ATOM 1169 C CG . ASP A 1 163 ? 13.419 8.680 -10.083 1.00 29.69 ? 163 ASP A CG 1 ATOM 1170 O OD1 . ASP A 1 163 ? 12.472 8.045 -9.567 1.00 30.47 ? 163 ASP A OD1 1 ATOM 1171 O OD2 . ASP A 1 163 ? 14.576 8.219 -10.197 1.00 26.65 ? 163 ASP A OD2 1 ATOM 1172 N N . ILE A 1 164 ? 11.465 12.230 -12.330 1.00 24.48 ? 164 ILE A N 1 ATOM 1173 C CA . ILE A 1 164 ? 11.134 13.598 -12.716 1.00 24.07 ? 164 ILE A CA 1 ATOM 1174 C C . ILE A 1 164 ? 9.702 13.927 -12.313 1.00 23.93 ? 164 ILE A C 1 ATOM 1175 O O . ILE A 1 164 ? 9.424 15.012 -11.783 1.00 24.30 ? 164 ILE A O 1 ATOM 1176 C CB . ILE A 1 164 ? 11.356 13.785 -14.230 1.00 25.16 ? 164 ILE A CB 1 ATOM 1177 C CG1 . ILE A 1 164 ? 12.851 13.850 -14.552 1.00 31.18 ? 164 ILE A CG1 1 ATOM 1178 C CG2 . ILE A 1 164 ? 10.613 15.003 -14.750 1.00 26.61 ? 164 ILE A CG2 1 ATOM 1179 C CD1 . ILE A 1 164 ? 13.169 13.695 -16.051 1.00 30.25 ? 164 ILE A CD1 1 ATOM 1180 N N . ASN A 1 165 ? 8.769 13.001 -12.569 1.00 21.67 ? 165 ASN A N 1 ATOM 1181 C CA . ASN A 1 165 ? 7.380 13.232 -12.171 1.00 22.03 ? 165 ASN A CA 1 ATOM 1182 C C . ASN A 1 165 ? 7.285 13.503 -10.679 1.00 21.12 ? 165 ASN A C 1 ATOM 1183 O O . ASN A 1 165 ? 6.518 14.367 -10.246 1.00 22.65 ? 165 ASN A O 1 ATOM 1184 C CB . ASN A 1 165 ? 6.491 12.035 -12.524 1.00 21.64 ? 165 ASN A CB 1 ATOM 1185 C CG . ASN A 1 165 ? 6.260 11.868 -14.017 1.00 27.37 ? 165 ASN A CG 1 ATOM 1186 O OD1 . ASN A 1 165 ? 6.239 12.842 -14.779 1.00 32.00 ? 165 ASN A OD1 1 ATOM 1187 N ND2 . ASN A 1 165 ? 6.065 10.618 -14.445 1.00 19.82 ? 165 ASN A ND2 1 ATOM 1188 N N . PHE A 1 166 ? 8.047 12.749 -9.877 1.00 22.77 ? 166 PHE A N 1 ATOM 1189 C CA . PHE A 1 166 ? 8.028 12.914 -8.425 1.00 21.77 ? 166 PHE A CA 1 ATOM 1190 C C . PHE A 1 166 ? 8.558 14.280 -8.018 1.00 23.30 ? 166 PHE A C 1 ATOM 1191 O O . PHE A 1 166 ? 7.918 15.004 -7.245 1.00 19.88 ? 166 PHE A O 1 ATOM 1192 C CB . PHE A 1 166 ? 8.853 11.806 -7.771 1.00 17.33 ? 166 PHE A CB 1 ATOM 1193 C CG . PHE A 1 166 ? 8.848 11.856 -6.271 1.00 21.86 ? 166 PHE A CG 1 ATOM 1194 C CD1 . PHE A 1 166 ? 7.656 11.779 -5.566 1.00 20.16 ? 166 PHE A CD1 1 ATOM 1195 C CD2 . PHE A 1 166 ? 10.037 11.966 -5.565 1.00 20.67 ? 166 PHE A CD2 1 ATOM 1196 C CE1 . PHE A 1 166 ? 7.649 11.825 -4.172 1.00 20.49 ? 166 PHE A CE1 1 ATOM 1197 C CE2 . PHE A 1 166 ? 10.036 12.003 -4.190 1.00 19.91 ? 166 PHE A CE2 1 ATOM 1198 C CZ . PHE A 1 166 ? 8.832 11.933 -3.489 1.00 20.22 ? 166 PHE A CZ 1 ATOM 1199 N N . ALA A 1 167 ? 9.730 14.655 -8.540 1.00 24.31 ? 167 ALA A N 1 ATOM 1200 C CA . ALA A 1 167 ? 10.312 15.953 -8.198 1.00 24.20 ? 167 ALA A CA 1 ATOM 1201 C C . ALA A 1 167 ? 9.382 17.101 -8.580 1.00 21.36 ? 167 ALA A C 1 ATOM 1202 O O . ALA A 1 167 ? 9.225 18.064 -7.815 1.00 21.20 ? 167 ALA A O 1 ATOM 1203 C CB . ALA A 1 167 ? 11.673 16.112 -8.880 1.00 26.31 ? 167 ALA A CB 1 ATOM 1204 N N . ASN A 1 168 ? 8.737 17.005 -9.745 1.00 23.53 ? 168 ASN A N 1 ATOM 1205 C CA . ASN A 1 168 ? 7.837 18.068 -10.185 1.00 23.18 ? 168 ASN A CA 1 ATOM 1206 C C . ASN A 1 168 ? 6.566 18.103 -9.350 1.00 24.97 ? 168 ASN A C 1 ATOM 1207 O O . ASN A 1 168 ? 6.053 19.182 -9.041 1.00 24.32 ? 168 ASN A O 1 ATOM 1208 C CB . ASN A 1 168 ? 7.490 17.880 -11.661 1.00 25.47 ? 168 ASN A CB 1 ATOM 1209 C CG . ASN A 1 168 ? 8.616 18.297 -12.567 1.00 27.89 ? 168 ASN A CG 1 ATOM 1210 O OD1 . ASN A 1 168 ? 9.445 19.129 -12.195 1.00 28.10 ? 168 ASN A OD1 1 ATOM 1211 N ND2 . ASN A 1 168 ? 8.650 17.735 -13.765 1.00 29.39 ? 168 ASN A ND2 1 ATOM 1212 N N . ALA A 1 169 ? 6.031 16.935 -8.987 1.00 21.98 ? 169 ALA A N 1 ATOM 1213 C CA . ALA A 1 169 ? 4.855 16.911 -8.128 1.00 21.20 ? 169 ALA A CA 1 ATOM 1214 C C . ALA A 1 169 ? 5.159 17.523 -6.761 1.00 20.70 ? 169 ALA A C 1 ATOM 1215 O O . ALA A 1 169 ? 4.343 18.270 -6.213 1.00 22.66 ? 169 ALA A O 1 ATOM 1216 C CB . ALA A 1 169 ? 4.329 15.478 -7.992 1.00 21.14 ? 169 ALA A CB 1 ATOM 1217 N N . VAL A 1 170 ? 6.334 17.230 -6.190 1.00 20.06 ? 170 VAL A N 1 ATOM 1218 C CA . VAL A 1 170 ? 6.673 17.821 -4.896 1.00 16.61 ? 170 VAL A CA 1 ATOM 1219 C C . VAL A 1 170 ? 6.710 19.345 -5.012 1.00 22.73 ? 170 VAL A C 1 ATOM 1220 O O . VAL A 1 170 ? 6.113 20.067 -4.203 1.00 23.54 ? 170 VAL A O 1 ATOM 1221 C CB . VAL A 1 170 ? 8.013 17.273 -4.367 1.00 19.09 ? 170 VAL A CB 1 ATOM 1222 C CG1 . VAL A 1 170 ? 8.439 18.046 -3.126 1.00 21.45 ? 170 VAL A CG1 1 ATOM 1223 C CG2 . VAL A 1 170 ? 7.904 15.782 -4.020 1.00 20.22 ? 170 VAL A CG2 1 ATOM 1224 N N . SER A 1 171 ? 7.420 19.855 -6.016 1.00 24.78 ? 171 SER A N 1 ATOM 1225 C CA . SER A 1 171 ? 7.475 21.305 -6.212 1.00 24.09 ? 171 SER A CA 1 ATOM 1226 C C . SER A 1 171 ? 6.087 21.893 -6.453 1.00 23.46 ? 171 SER A C 1 ATOM 1227 O O . SER A 1 171 ? 5.718 22.905 -5.842 1.00 24.69 ? 171 SER A O 1 ATOM 1228 C CB . SER A 1 171 ? 8.419 21.648 -7.369 1.00 23.65 ? 171 SER A CB 1 ATOM 1229 O OG . SER A 1 171 ? 8.550 23.060 -7.485 1.00 28.87 ? 171 SER A OG 1 ATOM 1230 N N . ASP A 1 172 ? 5.308 21.286 -7.357 1.00 23.82 ? 172 ASP A N 1 ATOM 1231 C CA . ASP A 1 172 ? 3.958 21.780 -7.624 1.00 25.57 ? 172 ASP A CA 1 ATOM 1232 C C . ASP A 1 172 ? 3.091 21.753 -6.367 1.00 26.63 ? 172 ASP A C 1 ATOM 1233 O O . ASP A 1 172 ? 2.294 22.669 -6.136 1.00 27.39 ? 172 ASP A O 1 ATOM 1234 C CB . ASP A 1 172 ? 3.297 20.964 -8.737 1.00 23.84 ? 172 ASP A CB 1 ATOM 1235 C CG . ASP A 1 172 ? 3.960 21.167 -10.096 1.00 35.19 ? 172 ASP A CG 1 ATOM 1236 O OD1 . ASP A 1 172 ? 4.661 22.183 -10.285 1.00 43.24 ? 172 ASP A OD1 1 ATOM 1237 O OD2 . ASP A 1 172 ? 3.774 20.306 -10.987 1.00 39.09 ? 172 ASP A OD2 1 ATOM 1238 N N . ALA A 1 173 ? 3.226 20.712 -5.540 1.00 22.03 ? 173 ALA A N 1 ATOM 1239 C CA . ALA A 1 173 ? 2.412 20.630 -4.332 1.00 20.77 ? 173 ALA A CA 1 ATOM 1240 C C . ALA A 1 173 ? 2.763 21.744 -3.356 1.00 25.68 ? 173 ALA A C 1 ATOM 1241 O O . ALA A 1 173 ? 1.871 22.351 -2.749 1.00 25.87 ? 173 ALA A O 1 ATOM 1242 C CB . ALA A 1 173 ? 2.585 19.266 -3.665 1.00 19.29 ? 173 ALA A CB 1 ATOM 1243 N N . LEU A 1 174 ? 4.057 22.018 -3.178 1.00 22.53 ? 174 LEU A N 1 ATOM 1244 C CA . LEU A 1 174 ? 4.444 23.115 -2.293 1.00 23.54 ? 174 LEU A CA 1 ATOM 1245 C C . LEU A 1 174 ? 3.863 24.442 -2.780 1.00 26.25 ? 174 LEU A C 1 ATOM 1246 O O . LEU A 1 174 ? 3.355 25.237 -1.975 1.00 26.77 ? 174 LEU A O 1 ATOM 1247 C CB . LEU A 1 174 ? 5.966 23.192 -2.178 1.00 21.96 ? 174 LEU A CB 1 ATOM 1248 C CG . LEU A 1 174 ? 6.695 22.009 -1.528 1.00 21.76 ? 174 LEU A CG 1 ATOM 1249 C CD1 . LEU A 1 174 ? 8.215 22.206 -1.501 1.00 21.86 ? 174 LEU A CD1 1 ATOM 1250 C CD2 . LEU A 1 174 ? 6.178 21.783 -0.124 1.00 22.83 ? 174 LEU A CD2 1 ATOM 1251 N N . ASP A 1 175 ? 3.886 24.677 -4.097 1.00 25.96 ? 175 ASP A N 1 ATOM 1252 C CA . ASP A 1 175 ? 3.274 25.889 -4.651 1.00 31.49 ? 175 ASP A CA 1 ATOM 1253 C C . ASP A 1 175 ? 1.780 25.947 -4.355 1.00 30.72 ? 175 ASP A C 1 ATOM 1254 O O . ASP A 1 175 ? 1.248 27.011 -4.011 1.00 30.71 ? 175 ASP A O 1 ATOM 1255 C CB . ASP A 1 175 ? 3.510 25.968 -6.157 1.00 31.93 ? 175 ASP A CB 1 ATOM 1256 C CG . ASP A 1 175 ? 4.945 26.314 -6.513 1.00 32.54 ? 175 ASP A CG 1 ATOM 1257 O OD1 . ASP A 1 175 ? 5.696 26.755 -5.618 1.00 34.89 ? 175 ASP A OD1 1 ATOM 1258 O OD2 . ASP A 1 175 ? 5.320 26.136 -7.692 1.00 35.68 ? 175 ASP A OD2 1 ATOM 1259 N N . SER A 1 176 ? 1.079 24.816 -4.485 1.00 26.99 ? 176 SER A N 1 ATOM 1260 C CA A SER A 1 176 ? -0.357 24.821 -4.227 0.50 29.50 ? 176 SER A CA 1 ATOM 1261 C CA B SER A 1 176 ? -0.358 24.808 -4.224 0.50 29.49 ? 176 SER A CA 1 ATOM 1262 C C . SER A 1 176 ? -0.662 25.032 -2.747 1.00 29.58 ? 176 SER A C 1 ATOM 1263 O O . SER A 1 176 ? -1.643 25.700 -2.408 1.00 30.62 ? 176 SER A O 1 ATOM 1264 C CB A SER A 1 176 ? -0.983 23.522 -4.731 0.50 27.13 ? 176 SER A CB 1 ATOM 1265 C CB B SER A 1 176 ? -0.979 23.496 -4.712 0.50 27.14 ? 176 SER A CB 1 ATOM 1266 O OG A SER A 1 176 ? -0.586 23.251 -6.066 0.50 25.26 ? 176 SER A OG 1 ATOM 1267 O OG B SER A 1 176 ? -0.381 22.363 -4.097 0.50 27.70 ? 176 SER A OG 1 ATOM 1268 N N . LEU A 1 177 ? 0.160 24.486 -1.856 1.00 24.83 ? 177 LEU A N 1 ATOM 1269 C CA . LEU A 1 177 ? -0.022 24.745 -0.430 1.00 24.00 ? 177 LEU A CA 1 ATOM 1270 C C . LEU A 1 177 ? 0.320 26.189 -0.071 1.00 31.01 ? 177 LEU A C 1 ATOM 1271 O O . LEU A 1 177 ? -0.364 26.808 0.754 1.00 32.08 ? 177 LEU A O 1 ATOM 1272 C CB . LEU A 1 177 ? 0.840 23.787 0.381 1.00 26.44 ? 177 LEU A CB 1 ATOM 1273 C CG . LEU A 1 177 ? 0.435 22.329 0.187 1.00 22.50 ? 177 LEU A CG 1 ATOM 1274 C CD1 . LEU A 1 177 ? 1.557 21.404 0.673 1.00 26.04 ? 177 LEU A CD1 1 ATOM 1275 C CD2 . LEU A 1 177 ? -0.887 22.042 0.911 1.00 24.78 ? 177 LEU A CD2 1 ATOM 1276 N N . LYS A 1 178 ? 1.395 26.728 -0.649 1.00 28.39 ? 178 LYS A N 1 ATOM 1277 C CA . LYS A 1 178 ? 1.796 28.095 -0.321 1.00 30.02 ? 178 LYS A CA 1 ATOM 1278 C C . LYS A 1 178 ? 0.736 29.093 -0.750 1.00 32.10 ? 178 LYS A C 1 ATOM 1279 O O . LYS A 1 178 ? 0.424 30.039 -0.017 1.00 32.00 ? 178 LYS A O 1 ATOM 1280 C CB . LYS A 1 178 ? 3.125 28.438 -0.990 1.00 31.46 ? 178 LYS A CB 1 ATOM 1281 C CG . LYS A 1 178 ? 3.612 29.837 -0.624 1.00 29.68 ? 178 LYS A CG 1 ATOM 1282 C CD . LYS A 1 178 ? 4.861 30.199 -1.381 1.00 41.11 ? 178 LYS A CD 1 ATOM 1283 C CE . LYS A 1 178 ? 5.292 31.636 -1.052 1.00 37.31 ? 178 LYS A CE 1 ATOM 1284 N NZ . LYS A 1 178 ? 6.358 32.095 -1.980 1.00 45.03 ? 178 LYS A NZ 1 ATOM 1285 N N . SER A 1 179 ? 0.160 28.884 -1.930 1.00 29.06 ? 179 SER A N 1 ATOM 1286 C CA . SER A 1 179 ? -0.834 29.790 -2.492 1.00 32.98 ? 179 SER A CA 1 ATOM 1287 C C . SER A 1 179 ? -2.213 29.606 -1.887 1.00 35.29 ? 179 SER A C 1 ATOM 1288 O O . SER A 1 179 ? -3.131 30.345 -2.259 1.00 40.38 ? 179 SER A O 1 ATOM 1289 C CB . SER A 1 179 ? -0.931 29.575 -4.000 1.00 33.96 ? 179 SER A CB 1 ATOM 1290 O OG . SER A 1 179 ? -1.528 28.316 -4.272 1.00 32.84 ? 179 SER A OG 1 ATOM 1291 N N . GLY A 1 180 ? -2.393 28.626 -1.005 1.00 34.08 ? 180 GLY A N 1 ATOM 1292 C CA . GLY A 1 180 ? -3.684 28.344 -0.418 1.00 33.83 ? 180 GLY A CA 1 ATOM 1293 C C . GLY A 1 180 ? -4.650 27.577 -1.301 1.00 32.01 ? 180 GLY A C 1 ATOM 1294 O O . GLY A 1 180 ? -5.781 27.318 -0.866 1.00 30.33 ? 180 GLY A O 1 ATOM 1295 N N . ARG A 1 181 ? -4.256 27.225 -2.528 1.00 26.40 ? 181 ARG A N 1 ATOM 1296 C CA . ARG A 1 181 ? -5.112 26.401 -3.379 1.00 26.69 ? 181 ARG A CA 1 ATOM 1297 C C . ARG A 1 181 ? -5.318 25.002 -2.814 1.00 28.80 ? 181 ARG A C 1 ATOM 1298 O O . ARG A 1 181 ? -6.300 24.344 -3.176 1.00 27.64 ? 181 ARG A O 1 ATOM 1299 C CB . ARG A 1 181 ? -4.525 26.301 -4.787 1.00 30.23 ? 181 ARG A CB 1 ATOM 1300 C CG . ARG A 1 181 ? -4.775 27.523 -5.657 1.00 31.39 ? 181 ARG A CG 1 ATOM 1301 C CD . ARG A 1 181 ? -4.109 27.402 -7.026 1.00 36.90 ? 181 ARG A CD 1 ATOM 1302 N NE . ARG A 1 181 ? -2.649 27.493 -6.936 1.00 44.55 ? 181 ARG A NE 1 ATOM 1303 C CZ . ARG A 1 181 ? -1.803 26.522 -7.279 1.00 45.57 ? 181 ARG A CZ 1 ATOM 1304 N NH1 . ARG A 1 181 ? -2.259 25.367 -7.756 1.00 38.99 ? 181 ARG A NH1 1 ATOM 1305 N NH2 . ARG A 1 181 ? -0.493 26.708 -7.149 1.00 44.75 ? 181 ARG A NH2 1 ATOM 1306 N N . ALA A 1 182 ? -4.396 24.527 -1.963 1.00 26.80 ? 182 ALA A N 1 ATOM 1307 C CA . ALA A 1 182 ? -4.495 23.238 -1.283 1.00 24.20 ? 182 ALA A CA 1 ATOM 1308 C C . ALA A 1 182 ? -4.265 23.424 0.207 1.00 27.22 ? 182 ALA A C 1 ATOM 1309 O O . ALA A 1 182 ? -3.430 24.229 0.625 1.00 28.43 ? 182 ALA A O 1 ATOM 1310 C CB . ALA A 1 182 ? -3.475 22.217 -1.821 1.00 26.72 ? 182 ALA A CB 1 ATOM 1311 N N . ASP A 1 183 ? -5.035 22.691 1.002 1.00 27.46 ? 183 ASP A N 1 ATOM 1312 C CA . ASP A 1 183 ? -4.793 22.529 2.425 1.00 25.17 ? 183 ASP A CA 1 ATOM 1313 C C . ASP A 1 183 ? -4.048 21.242 2.729 1.00 27.45 ? 183 ASP A C 1 ATOM 1314 O O . ASP A 1 183 ? -3.232 21.204 3.654 1.00 25.08 ? 183 ASP A O 1 ATOM 1315 C CB . ASP A 1 183 ? -6.125 22.527 3.181 1.00 29.86 ? 183 ASP A CB 1 ATOM 1316 C CG . ASP A 1 183 ? -6.862 23.837 3.041 1.00 35.34 ? 183 ASP A CG 1 ATOM 1317 O OD1 . ASP A 1 183 ? -6.200 24.880 3.211 1.00 36.04 ? 183 ASP A OD1 1 ATOM 1318 O OD2 . ASP A 1 183 ? -8.076 23.834 2.735 1.00 34.25 ? 183 ASP A OD2 1 ATOM 1319 N N . LEU A 1 184 ? -4.332 20.193 1.962 1.00 25.19 ? 184 LEU A N 1 ATOM 1320 C CA . LEU A 1 184 ? -3.607 18.932 2.011 1.00 23.19 ? 184 LEU A CA 1 ATOM 1321 C C . LEU A 1 184 ? -3.134 18.630 0.605 1.00 20.82 ? 184 LEU A C 1 ATOM 1322 O O . LEU A 1 184 ? -3.916 18.744 -0.342 1.00 20.78 ? 184 LEU A O 1 ATOM 1323 C CB . LEU A 1 184 ? -4.494 17.784 2.510 1.00 25.73 ? 184 LEU A CB 1 ATOM 1324 C CG . LEU A 1 184 ? -3.965 16.386 2.140 1.00 20.20 ? 184 LEU A CG 1 ATOM 1325 C CD1 . LEU A 1 184 ? -2.706 16.094 2.931 1.00 24.33 ? 184 LEU A CD1 1 ATOM 1326 C CD2 . LEU A 1 184 ? -5.011 15.298 2.362 1.00 28.23 ? 184 LEU A CD2 1 ATOM 1327 N N . ALA A 1 185 ? -1.870 18.239 0.458 1.00 19.34 ? 185 ALA A N 1 ATOM 1328 C CA . ALA A 1 185 ? -1.384 17.696 -0.804 1.00 18.01 ? 185 ALA A CA 1 ATOM 1329 C C . ALA A 1 185 ? -0.826 16.306 -0.549 1.00 16.32 ? 185 ALA A C 1 ATOM 1330 O O . ALA A 1 185 ? -0.113 16.098 0.431 1.00 19.96 ? 185 ALA A O 1 ATOM 1331 C CB . ALA A 1 185 ? -0.313 18.585 -1.435 1.00 17.80 ? 185 ALA A CB 1 ATOM 1332 N N . ALA A 1 186 ? -1.153 15.367 -1.428 1.00 18.77 ? 186 ALA A N 1 ATOM 1333 C CA . ALA A 1 186 ? -0.783 13.966 -1.251 1.00 16.81 ? 186 ALA A CA 1 ATOM 1334 C C . ALA A 1 186 ? -0.135 13.479 -2.538 1.00 14.67 ? 186 ALA A C 1 ATOM 1335 O O . ALA A 1 186 ? -0.697 13.655 -3.624 1.00 18.52 ? 186 ALA A O 1 ATOM 1336 C CB . ALA A 1 186 ? -2.016 13.126 -0.881 1.00 18.63 ? 186 ALA A CB 1 ATOM 1337 N N . ILE A 1 187 ? 1.058 12.894 -2.427 1.00 16.18 ? 187 ILE A N 1 ATOM 1338 C CA . ILE A 1 187 ? 1.844 12.503 -3.592 1.00 17.01 ? 187 ILE A CA 1 ATOM 1339 C C . ILE A 1 187 ? 2.197 11.033 -3.444 1.00 16.81 ? 187 ILE A C 1 ATOM 1340 O O . ILE A 1 187 ? 2.636 10.613 -2.369 1.00 18.95 ? 187 ILE A O 1 ATOM 1341 C CB . ILE A 1 187 ? 3.134 13.332 -3.734 1.00 16.57 ? 187 ILE A CB 1 ATOM 1342 C CG1 . ILE A 1 187 ? 2.807 14.819 -3.744 1.00 18.71 ? 187 ILE A CG1 1 ATOM 1343 C CG2 . ILE A 1 187 ? 3.863 12.923 -5.024 1.00 18.83 ? 187 ILE A CG2 1 ATOM 1344 C CD1 . ILE A 1 187 ? 4.039 15.706 -3.809 1.00 20.83 ? 187 ILE A CD1 1 ATOM 1345 N N . TYR A 1 188 ? 2.048 10.275 -4.531 1.00 17.86 ? 188 TYR A N 1 ATOM 1346 C CA . TYR A 1 188 ? 2.367 8.854 -4.569 1.00 17.43 ? 188 TYR A CA 1 ATOM 1347 C C . TYR A 1 188 ? 3.565 8.610 -5.481 1.00 17.87 ? 188 TYR A C 1 ATOM 1348 O O . TYR A 1 188 ? 3.629 9.159 -6.584 1.00 17.81 ? 188 TYR A O 1 ATOM 1349 C CB . TYR A 1 188 ? 1.147 8.054 -5.040 1.00 15.46 ? 188 TYR A CB 1 ATOM 1350 C CG . TYR A 1 188 ? 1.458 6.622 -5.393 1.00 17.66 ? 188 TYR A CG 1 ATOM 1351 C CD1 . TYR A 1 188 ? 1.648 5.671 -4.399 1.00 21.94 ? 188 TYR A CD1 1 ATOM 1352 C CD2 . TYR A 1 188 ? 1.562 6.226 -6.719 1.00 18.41 ? 188 TYR A CD2 1 ATOM 1353 C CE1 . TYR A 1 188 ? 1.942 4.346 -4.717 1.00 17.53 ? 188 TYR A CE1 1 ATOM 1354 C CE2 . TYR A 1 188 ? 1.854 4.906 -7.054 1.00 21.33 ? 188 TYR A CE2 1 ATOM 1355 C CZ . TYR A 1 188 ? 2.039 3.975 -6.045 1.00 21.69 ? 188 TYR A CZ 1 ATOM 1356 O OH . TYR A 1 188 ? 2.337 2.676 -6.373 1.00 20.28 ? 188 TYR A OH 1 ATOM 1357 N N . HIS A 1 189 ? 4.501 7.757 -5.028 1.00 17.41 ? 189 HIS A N 1 ATOM 1358 C CA . HIS A 1 189 ? 5.694 7.392 -5.785 1.00 18.62 ? 189 HIS A CA 1 ATOM 1359 C C . HIS A 1 189 ? 5.844 5.875 -5.749 1.00 19.89 ? 189 HIS A C 1 ATOM 1360 O O . HIS A 1 189 ? 5.782 5.283 -4.670 1.00 19.96 ? 189 HIS A O 1 ATOM 1361 C CB . HIS A 1 189 ? 6.953 8.050 -5.188 1.00 18.82 ? 189 HIS A CB 1 ATOM 1362 C CG . HIS A 1 189 ? 8.198 7.812 -5.987 1.00 19.85 ? 189 HIS A CG 1 ATOM 1363 N ND1 . HIS A 1 189 ? 8.396 8.362 -7.235 1.00 22.85 ? 189 HIS A ND1 1 ATOM 1364 C CD2 . HIS A 1 189 ? 9.315 7.096 -5.711 1.00 22.11 ? 189 HIS A CD2 1 ATOM 1365 C CE1 . HIS A 1 189 ? 9.577 7.993 -7.699 1.00 24.54 ? 189 HIS A CE1 1 ATOM 1366 N NE2 . HIS A 1 189 ? 10.158 7.229 -6.790 1.00 23.71 ? 189 HIS A NE2 1 ATOM 1367 N N . GLU A 1 190 ? 6.060 5.248 -6.918 1.00 20.06 ? 190 GLU A N 1 ATOM 1368 C CA . GLU A 1 190 ? 6.059 3.786 -7.035 1.00 19.41 ? 190 GLU A CA 1 ATOM 1369 C C . GLU A 1 190 ? 7.430 3.149 -7.261 1.00 20.25 ? 190 GLU A C 1 ATOM 1370 O O . GLU A 1 190 ? 7.582 1.940 -7.027 1.00 20.95 ? 190 GLU A O 1 ATOM 1371 C CB . GLU A 1 190 ? 5.139 3.362 -8.194 1.00 23.18 ? 190 GLU A CB 1 ATOM 1372 C CG . GLU A 1 190 ? 4.895 1.862 -8.301 1.00 22.99 ? 190 GLU A CG 1 ATOM 1373 C CD . GLU A 1 190 ? 3.977 1.508 -9.451 1.00 27.68 ? 190 GLU A CD 1 ATOM 1374 O OE1 . GLU A 1 190 ? 3.650 2.404 -10.257 1.00 25.35 ? 190 GLU A OE1 1 ATOM 1375 O OE2 . GLU A 1 190 ? 3.581 0.328 -9.553 1.00 26.18 ? 190 GLU A OE2 1 ATOM 1376 N N . ARG A 1 191 ? 8.425 3.906 -7.712 1.00 21.44 ? 191 ARG A N 1 ATOM 1377 C CA . ARG A 1 191 ? 9.578 3.268 -8.346 1.00 21.28 ? 191 ARG A CA 1 ATOM 1378 C C . ARG A 1 191 ? 10.421 2.435 -7.372 1.00 22.61 ? 191 ARG A C 1 ATOM 1379 O O . ARG A 1 191 ? 11.101 1.500 -7.807 1.00 24.31 ? 191 ARG A O 1 ATOM 1380 C CB . ARG A 1 191 ? 10.432 4.318 -9.067 1.00 22.86 ? 191 ARG A CB 1 ATOM 1381 C CG . ARG A 1 191 ? 11.109 3.738 -10.311 1.00 37.66 ? 191 ARG A CG 1 ATOM 1382 C CD . ARG A 1 191 ? 11.749 4.786 -11.211 1.00 35.65 ? 191 ARG A CD 1 ATOM 1383 N NE . ARG A 1 191 ? 12.968 5.343 -10.633 1.00 34.46 ? 191 ARG A NE 1 ATOM 1384 C CZ . ARG A 1 191 ? 14.140 4.726 -10.615 1.00 28.75 ? 191 ARG A CZ 1 ATOM 1385 N NH1 . ARG A 1 191 ? 14.265 3.512 -11.136 1.00 34.38 ? 191 ARG A NH1 1 ATOM 1386 N NH2 . ARG A 1 191 ? 15.189 5.330 -10.066 1.00 35.36 ? 191 ARG A NH2 1 ATOM 1387 N N . ILE A 1 192 ? 10.366 2.705 -6.062 1.00 19.57 ? 192 ILE A N 1 ATOM 1388 C CA . ILE A 1 192 ? 11.118 1.847 -5.149 1.00 18.30 ? 192 ILE A CA 1 ATOM 1389 C C . ILE A 1 192 ? 10.497 0.451 -5.112 1.00 21.34 ? 192 ILE A C 1 ATOM 1390 O O . ILE A 1 192 ? 11.215 -0.561 -5.036 1.00 20.86 ? 192 ILE A O 1 ATOM 1391 C CB . ILE A 1 192 ? 11.224 2.499 -3.755 1.00 16.34 ? 192 ILE A CB 1 ATOM 1392 C CG1 . ILE A 1 192 ? 12.143 3.724 -3.826 1.00 21.64 ? 192 ILE A CG1 1 ATOM 1393 C CG2 . ILE A 1 192 ? 11.801 1.519 -2.715 1.00 19.76 ? 192 ILE A CG2 1 ATOM 1394 C CD1 . ILE A 1 192 ? 12.045 4.645 -2.600 1.00 24.16 ? 192 ILE A CD1 1 ATOM 1395 N N . ASP A 1 193 ? 9.168 0.374 -5.218 1.00 19.22 ? 193 ASP A N 1 ATOM 1396 C CA . ASP A 1 193 ? 8.472 -0.900 -5.346 1.00 20.99 ? 193 ASP A CA 1 ATOM 1397 C C . ASP A 1 193 ? 8.845 -1.602 -6.649 1.00 19.90 ? 193 ASP A C 1 ATOM 1398 O O . ASP A 1 193 ? 9.180 -2.794 -6.650 1.00 20.63 ? 193 ASP A O 1 ATOM 1399 C CB . ASP A 1 193 ? 6.956 -0.653 -5.263 1.00 19.17 ? 193 ASP A CB 1 ATOM 1400 C CG . ASP A 1 193 ? 6.139 -1.937 -5.122 1.00 19.89 ? 193 ASP A CG 1 ATOM 1401 O OD1 . ASP A 1 193 ? 6.259 -2.613 -4.087 1.00 21.84 ? 193 ASP A OD1 1 ATOM 1402 O OD2 . ASP A 1 193 ? 5.343 -2.245 -6.036 1.00 22.77 ? 193 ASP A OD2 1 ATOM 1403 N N . VAL A 1 194 ? 8.801 -0.881 -7.770 1.00 21.08 ? 194 VAL A N 1 ATOM 1404 C CA . VAL A 1 194 ? 9.090 -1.515 -9.065 1.00 26.47 ? 194 VAL A CA 1 ATOM 1405 C C . VAL A 1 194 ? 10.478 -2.157 -9.066 1.00 23.34 ? 194 VAL A C 1 ATOM 1406 O O . VAL A 1 194 ? 10.655 -3.303 -9.511 1.00 21.88 ? 194 VAL A O 1 ATOM 1407 C CB . VAL A 1 194 ? 8.954 -0.501 -10.214 1.00 24.38 ? 194 VAL A CB 1 ATOM 1408 C CG1 . VAL A 1 194 ? 9.388 -1.171 -11.532 1.00 24.60 ? 194 VAL A CG1 1 ATOM 1409 C CG2 . VAL A 1 194 ? 7.526 0.016 -10.322 1.00 23.49 ? 194 VAL A CG2 1 ATOM 1410 N N . GLU A 1 195 ? 11.490 -1.421 -8.597 1.00 21.65 ? 195 GLU A N 1 ATOM 1411 C CA . GLU A 1 195 ? 12.849 -1.971 -8.625 1.00 25.62 ? 195 GLU A CA 1 ATOM 1412 C C . GLU A 1 195 ? 13.025 -3.081 -7.598 1.00 24.87 ? 195 GLU A C 1 ATOM 1413 O O . GLU A 1 195 ? 13.794 -4.026 -7.832 1.00 25.30 ? 195 GLU A O 1 ATOM 1414 C CB . GLU A 1 195 ? 13.892 -0.868 -8.387 1.00 23.32 ? 195 GLU A CB 1 ATOM 1415 C CG . GLU A 1 195 ? 13.815 0.290 -9.380 1.00 25.21 ? 195 GLU A CG 1 ATOM 1416 C CD . GLU A 1 195 ? 14.115 -0.151 -10.801 1.00 33.94 ? 195 GLU A CD 1 ATOM 1417 O OE1 . GLU A 1 195 ? 15.296 -0.095 -11.202 1.00 39.99 ? 195 GLU A OE1 1 ATOM 1418 O OE2 . GLU A 1 195 ? 13.177 -0.571 -11.511 1.00 36.48 ? 195 GLU A OE2 1 ATOM 1419 N N . GLY A 1 196 ? 12.349 -2.978 -6.450 1.00 22.29 ? 196 GLY A N 1 ATOM 1420 C CA . GLY A 1 196 ? 12.353 -4.086 -5.506 1.00 22.74 ? 196 GLY A CA 1 ATOM 1421 C C . GLY A 1 196 ? 11.795 -5.362 -6.113 1.00 22.86 ? 196 GLY A C 1 ATOM 1422 O O . GLY A 1 196 ? 12.330 -6.454 -5.893 1.00 24.47 ? 196 GLY A O 1 ATOM 1423 N N . HIS A 1 197 ? 10.738 -5.232 -6.919 1.00 19.66 ? 197 HIS A N 1 ATOM 1424 C CA . HIS A 1 197 ? 10.146 -6.378 -7.610 1.00 23.30 ? 197 HIS A CA 1 ATOM 1425 C C . HIS A 1 197 ? 11.082 -6.928 -8.679 1.00 22.74 ? 197 HIS A C 1 ATOM 1426 O O . HIS A 1 197 ? 11.351 -8.134 -8.731 1.00 24.18 ? 197 HIS A O 1 ATOM 1427 C CB . HIS A 1 197 ? 8.833 -5.963 -8.281 1.00 21.12 ? 197 HIS A CB 1 ATOM 1428 C CG . HIS A 1 197 ? 7.644 -5.926 -7.374 1.00 22.39 ? 197 HIS A CG 1 ATOM 1429 N ND1 . HIS A 1 197 ? 7.222 -7.017 -6.645 1.00 22.48 ? 197 HIS A ND1 1 ATOM 1430 C CD2 . HIS A 1 197 ? 6.750 -4.938 -7.126 1.00 21.88 ? 197 HIS A CD2 1 ATOM 1431 C CE1 . HIS A 1 197 ? 6.127 -6.699 -5.977 1.00 26.26 ? 197 HIS A CE1 1 ATOM 1432 N NE2 . HIS A 1 197 ? 5.817 -5.447 -6.258 1.00 21.53 ? 197 HIS A NE2 1 ATOM 1433 N N . HIS A 1 198 ? 11.567 -6.049 -9.561 1.00 22.87 ? 198 HIS A N 1 ATOM 1434 C CA . HIS A 1 198 ? 12.253 -6.494 -10.770 1.00 24.45 ? 198 HIS A CA 1 ATOM 1435 C C . HIS A 1 198 ? 13.644 -7.032 -10.473 1.00 25.36 ? 198 HIS A C 1 ATOM 1436 O O . HIS A 1 198 ? 14.114 -7.945 -11.164 1.00 27.31 ? 198 HIS A O 1 ATOM 1437 C CB . HIS A 1 198 ? 12.339 -5.344 -11.784 1.00 24.14 ? 198 HIS A CB 1 ATOM 1438 C CG . HIS A 1 198 ? 11.031 -5.001 -12.425 1.00 24.84 ? 198 HIS A CG 1 ATOM 1439 N ND1 . HIS A 1 198 ? 10.884 -3.932 -13.283 1.00 27.73 ? 198 HIS A ND1 1 ATOM 1440 C CD2 . HIS A 1 198 ? 9.812 -5.589 -12.342 1.00 26.76 ? 198 HIS A CD2 1 ATOM 1441 C CE1 . HIS A 1 198 ? 9.631 -3.872 -13.698 1.00 26.32 ? 198 HIS A CE1 1 ATOM 1442 N NE2 . HIS A 1 198 ? 8.961 -4.869 -13.145 1.00 26.89 ? 198 HIS A NE2 1 ATOM 1443 N N . TYR A 1 199 ? 14.323 -6.475 -9.473 1.00 25.69 ? 199 TYR A N 1 ATOM 1444 C CA . TYR A 1 199 ? 15.698 -6.843 -9.188 1.00 30.91 ? 199 TYR A CA 1 ATOM 1445 C C . TYR A 1 199 ? 15.921 -7.372 -7.783 1.00 28.77 ? 199 TYR A C 1 ATOM 1446 O O . TYR A 1 199 ? 16.973 -7.969 -7.534 1.00 31.78 ? 199 TYR A O 1 ATOM 1447 C CB . TYR A 1 199 ? 16.620 -5.638 -9.428 1.00 28.93 ? 199 TYR A CB 1 ATOM 1448 C CG . TYR A 1 199 ? 16.596 -5.147 -10.847 1.00 31.96 ? 199 TYR A CG 1 ATOM 1449 C CD1 . TYR A 1 199 ? 17.420 -5.722 -11.810 1.00 30.55 ? 199 TYR A CD1 1 ATOM 1450 C CD2 . TYR A 1 199 ? 15.757 -4.110 -11.230 1.00 29.05 ? 199 TYR A CD2 1 ATOM 1451 C CE1 . TYR A 1 199 ? 17.407 -5.277 -13.111 1.00 34.23 ? 199 TYR A CE1 1 ATOM 1452 C CE2 . TYR A 1 199 ? 15.735 -3.654 -12.528 1.00 33.07 ? 199 TYR A CE2 1 ATOM 1453 C CZ . TYR A 1 199 ? 16.563 -4.245 -13.468 1.00 34.14 ? 199 TYR A CZ 1 ATOM 1454 O OH . TYR A 1 199 ? 16.546 -3.794 -14.761 1.00 36.75 ? 199 TYR A OH 1 ATOM 1455 N N . GLY A 1 200 ? 14.969 -7.195 -6.865 1.00 25.58 ? 200 GLY A N 1 ATOM 1456 C CA . GLY A 1 200 ? 15.111 -7.688 -5.515 1.00 22.82 ? 200 GLY A CA 1 ATOM 1457 C C . GLY A 1 200 ? 15.337 -6.566 -4.518 1.00 22.34 ? 200 GLY A C 1 ATOM 1458 O O . GLY A 1 200 ? 15.870 -5.505 -4.858 1.00 22.75 ? 200 GLY A O 1 ATOM 1459 N N . PRO A 1 201 ? 14.924 -6.779 -3.264 1.00 23.11 ? 201 PRO A N 1 ATOM 1460 C CA . PRO A 1 201 ? 15.067 -5.713 -2.259 1.00 23.48 ? 201 PRO A CA 1 ATOM 1461 C C . PRO A 1 201 ? 16.510 -5.333 -1.961 1.00 27.08 ? 201 PRO A C 1 ATOM 1462 O O . PRO A 1 201 ? 16.756 -4.188 -1.569 1.00 24.66 ? 201 PRO A O 1 ATOM 1463 C CB . PRO A 1 201 ? 14.369 -6.296 -1.020 1.00 24.01 ? 201 PRO A CB 1 ATOM 1464 C CG . PRO A 1 201 ? 14.399 -7.796 -1.236 1.00 24.51 ? 201 PRO A CG 1 ATOM 1465 C CD . PRO A 1 201 ? 14.258 -7.973 -2.723 1.00 25.74 ? 201 PRO A CD 1 ATOM 1466 N N . SER A 1 202 ? 17.479 -6.240 -2.119 1.00 26.12 ? 202 SER A N 1 ATOM 1467 C CA A SER A 1 202 ? 18.874 -5.922 -1.842 0.50 27.43 ? 202 SER A CA 1 ATOM 1468 C CA B SER A 1 202 ? 18.873 -5.916 -1.841 0.50 27.43 ? 202 SER A CA 1 ATOM 1469 C C . SER A 1 202 ? 19.645 -5.477 -3.086 1.00 27.79 ? 202 SER A C 1 ATOM 1470 O O . SER A 1 202 ? 20.869 -5.338 -3.026 1.00 31.46 ? 202 SER A O 1 ATOM 1471 C CB A SER A 1 202 ? 19.569 -7.131 -1.202 0.50 28.09 ? 202 SER A CB 1 ATOM 1472 C CB B SER A 1 202 ? 19.575 -7.112 -1.183 0.50 28.09 ? 202 SER A CB 1 ATOM 1473 O OG A SER A 1 202 ? 19.509 -8.256 -2.060 0.50 26.74 ? 202 SER A OG 1 ATOM 1474 O OG B SER A 1 202 ? 19.002 -7.415 0.077 0.50 26.97 ? 202 SER A OG 1 ATOM 1475 N N . SER A 1 203 ? 18.964 -5.232 -4.198 1.00 24.54 ? 203 SER A N 1 ATOM 1476 C CA . SER A 1 203 ? 19.634 -4.964 -5.467 1.00 26.52 ? 203 SER A CA 1 ATOM 1477 C C . SER A 1 203 ? 20.175 -3.533 -5.543 1.00 31.61 ? 203 SER A C 1 ATOM 1478 O O . SER A 1 203 ? 19.653 -2.620 -4.890 1.00 28.96 ? 203 SER A O 1 ATOM 1479 C CB . SER A 1 203 ? 18.669 -5.188 -6.625 1.00 29.33 ? 203 SER A CB 1 ATOM 1480 O OG . SER A 1 203 ? 17.642 -4.204 -6.618 1.00 28.70 ? 203 SER A OG 1 ATOM 1481 N N . PRO A 1 204 ? 21.225 -3.306 -6.342 1.00 31.74 ? 204 PRO A N 1 ATOM 1482 C CA . PRO A 1 204 ? 21.653 -1.920 -6.586 1.00 31.68 ? 204 PRO A CA 1 ATOM 1483 C C . PRO A 1 204 ? 20.589 -1.100 -7.291 1.00 30.26 ? 204 PRO A C 1 ATOM 1484 O O . PRO A 1 204 ? 20.505 0.113 -7.061 1.00 30.39 ? 204 PRO A O 1 ATOM 1485 C CB . PRO A 1 204 ? 22.918 -2.079 -7.448 1.00 35.56 ? 204 PRO A CB 1 ATOM 1486 C CG . PRO A 1 204 ? 22.859 -3.477 -7.990 1.00 35.06 ? 204 PRO A CG 1 ATOM 1487 C CD . PRO A 1 204 ? 22.130 -4.287 -6.967 1.00 31.22 ? 204 PRO A CD 1 ATOM 1488 N N . GLN A 1 205 ? 19.757 -1.733 -8.125 1.00 27.31 ? 205 GLN A N 1 ATOM 1489 C CA . GLN A 1 205 ? 18.681 -1.006 -8.798 1.00 26.37 ? 205 GLN A CA 1 ATOM 1490 C C . GLN A 1 205 ? 17.673 -0.450 -7.794 1.00 25.56 ? 205 GLN A C 1 ATOM 1491 O O . GLN A 1 205 ? 17.180 0.678 -7.949 1.00 26.36 ? 205 GLN A O 1 ATOM 1492 C CB . GLN A 1 205 ? 17.972 -1.920 -9.799 1.00 29.37 ? 205 GLN A CB 1 ATOM 1493 C CG . GLN A 1 205 ? 18.813 -2.348 -10.992 1.00 33.77 ? 205 GLN A CG 1 ATOM 1494 C CD . GLN A 1 205 ? 19.780 -3.485 -10.679 1.00 32.93 ? 205 GLN A CD 1 ATOM 1495 O OE1 . GLN A 1 205 ? 19.694 -4.126 -9.637 1.00 31.17 ? 205 GLN A OE1 1 ATOM 1496 N NE2 . GLN A 1 205 ? 20.713 -3.736 -11.597 1.00 37.38 ? 205 GLN A NE2 1 ATOM 1497 N N . ARG A 1 206 ? 17.326 -1.233 -6.776 1.00 22.54 ? 206 ARG A N 1 ATOM 1498 C CA . ARG A 1 206 ? 16.435 -0.710 -5.745 1.00 26.19 ? 206 ARG A CA 1 ATOM 1499 C C . ARG A 1 206 ? 17.129 0.409 -4.975 1.00 25.03 ? 206 ARG A C 1 ATOM 1500 O O . ARG A 1 206 ? 16.529 1.449 -4.693 1.00 22.02 ? 206 ARG A O 1 ATOM 1501 C CB . ARG A 1 206 ? 15.977 -1.843 -4.815 1.00 23.33 ? 206 ARG A CB 1 ATOM 1502 C CG . ARG A 1 206 ? 14.881 -1.471 -3.791 1.00 21.30 ? 206 ARG A CG 1 ATOM 1503 C CD . ARG A 1 206 ? 15.451 -0.744 -2.564 1.00 23.32 ? 206 ARG A CD 1 ATOM 1504 N NE . ARG A 1 206 ? 16.424 -1.545 -1.823 1.00 20.27 ? 206 ARG A NE 1 ATOM 1505 C CZ . ARG A 1 206 ? 17.205 -1.080 -0.848 1.00 26.59 ? 206 ARG A CZ 1 ATOM 1506 N NH1 . ARG A 1 206 ? 17.160 0.199 -0.505 1.00 28.80 ? 206 ARG A NH1 1 ATOM 1507 N NH2 . ARG A 1 206 ? 18.039 -1.901 -0.205 1.00 27.26 ? 206 ARG A NH2 1 ATOM 1508 N N . LYS A 1 207 ? 18.405 0.214 -4.626 1.00 22.72 ? 207 LYS A N 1 ATOM 1509 C CA . LYS A 1 207 ? 19.127 1.262 -3.907 1.00 24.30 ? 207 LYS A CA 1 ATOM 1510 C C . LYS A 1 207 ? 19.250 2.533 -4.743 1.00 26.40 ? 207 LYS A C 1 ATOM 1511 O O . LYS A 1 207 ? 19.182 3.647 -4.201 1.00 26.88 ? 207 LYS A O 1 ATOM 1512 C CB . LYS A 1 207 ? 20.506 0.747 -3.467 1.00 26.04 ? 207 LYS A CB 1 ATOM 1513 C CG . LYS A 1 207 ? 20.407 -0.351 -2.420 1.00 23.17 ? 207 LYS A CG 1 ATOM 1514 C CD . LYS A 1 207 ? 21.776 -0.924 -2.051 1.00 36.93 ? 207 LYS A CD 1 ATOM 1515 C CE . LYS A 1 207 ? 21.623 -2.103 -1.118 1.00 37.92 ? 207 LYS A CE 1 ATOM 1516 N NZ . LYS A 1 207 ? 22.925 -2.774 -0.886 1.00 38.61 ? 207 LYS A NZ 1 ATOM 1517 N N . ASP A 1 208 ? 19.414 2.395 -6.065 1.00 26.44 ? 208 ASP A N 1 ATOM 1518 C CA . ASP A 1 208 ? 19.452 3.578 -6.926 1.00 28.36 ? 208 ASP A CA 1 ATOM 1519 C C . ASP A 1 208 ? 18.133 4.339 -6.885 1.00 29.41 ? 208 ASP A C 1 ATOM 1520 O O . ASP A 1 208 ? 18.125 5.575 -6.864 1.00 26.56 ? 208 ASP A O 1 ATOM 1521 C CB . ASP A 1 208 ? 19.788 3.196 -8.372 1.00 26.35 ? 208 ASP A CB 1 ATOM 1522 C CG . ASP A 1 208 ? 21.287 3.009 -8.598 1.00 42.46 ? 208 ASP A CG 1 ATOM 1523 O OD1 . ASP A 1 208 ? 22.086 3.473 -7.752 1.00 45.90 ? 208 ASP A OD1 1 ATOM 1524 O OD2 . ASP A 1 208 ? 21.669 2.409 -9.628 1.00 44.51 ? 208 ASP A OD2 1 ATOM 1525 N N . ALA A 1 209 ? 17.007 3.623 -6.883 1.00 24.03 ? 209 ALA A N 1 ATOM 1526 C CA . ALA A 1 209 ? 15.721 4.315 -6.838 1.00 23.95 ? 209 ALA A CA 1 ATOM 1527 C C . ALA A 1 209 ? 15.512 5.001 -5.489 1.00 22.14 ? 209 ALA A C 1 ATOM 1528 O O . ALA A 1 209 ? 14.917 6.085 -5.419 1.00 25.42 ? 209 ALA A O 1 ATOM 1529 C CB . ALA A 1 209 ? 14.580 3.339 -7.138 1.00 24.98 ? 209 ALA A CB 1 ATOM 1530 N N . LEU A 1 210 ? 15.990 4.385 -4.410 1.00 23.00 ? 210 LEU A N 1 ATOM 1531 C CA . LEU A 1 210 ? 15.919 5.021 -3.098 1.00 22.05 ? 210 LEU A CA 1 ATOM 1532 C C . LEU A 1 210 ? 16.777 6.279 -3.058 1.00 27.14 ? 210 LEU A C 1 ATOM 1533 O O . LEU A 1 210 ? 16.334 7.331 -2.573 1.00 25.02 ? 210 LEU A O 1 ATOM 1534 C CB . LEU A 1 210 ? 16.352 4.023 -2.019 1.00 23.95 ? 210 LEU A CB 1 ATOM 1535 C CG . LEU A 1 210 ? 16.579 4.589 -0.610 1.00 27.51 ? 210 LEU A CG 1 ATOM 1536 C CD1 . LEU A 1 210 ? 15.364 5.343 -0.145 1.00 30.21 ? 210 LEU A CD1 1 ATOM 1537 C CD2 . LEU A 1 210 ? 16.920 3.478 0.376 1.00 36.86 ? 210 LEU A CD2 1 ATOM 1538 N N . ARG A 1 211 ? 18.002 6.184 -3.583 1.00 27.81 ? 211 ARG A N 1 ATOM 1539 C CA . ARG A 1 211 ? 18.897 7.334 -3.665 1.00 30.54 ? 211 ARG A CA 1 ATOM 1540 C C . ARG A 1 211 ? 18.242 8.505 -4.386 1.00 25.66 ? 211 ARG A C 1 ATOM 1541 O O . ARG A 1 211 ? 18.370 9.657 -3.949 1.00 25.41 ? 211 ARG A O 1 ATOM 1542 C CB . ARG A 1 211 ? 20.194 6.916 -4.369 1.00 27.65 ? 211 ARG A CB 1 ATOM 1543 C CG . ARG A 1 211 ? 21.100 8.056 -4.781 1.00 38.38 ? 211 ARG A CG 1 ATOM 1544 C CD . ARG A 1 211 ? 21.770 8.672 -3.578 1.00 43.91 ? 211 ARG A CD 1 ATOM 1545 N NE . ARG A 1 211 ? 22.573 7.692 -2.858 1.00 52.29 ? 211 ARG A NE 1 ATOM 1546 C CZ . ARG A 1 211 ? 23.093 7.905 -1.655 1.00 48.67 ? 211 ARG A CZ 1 ATOM 1547 N NH1 . ARG A 1 211 ? 22.888 9.060 -1.039 1.00 51.30 ? 211 ARG A NH1 1 ATOM 1548 N NH2 . ARG A 1 211 ? 23.808 6.964 -1.060 1.00 51.60 ? 211 ARG A NH2 1 ATOM 1549 N N . ALA A 1 212 ? 17.522 8.232 -5.485 1.00 22.79 ? 212 ALA A N 1 ATOM 1550 C CA . ALA A 1 212 ? 16.860 9.310 -6.216 1.00 23.23 ? 212 ALA A CA 1 ATOM 1551 C C . ALA A 1 212 ? 15.810 9.994 -5.352 1.00 27.51 ? 212 ALA A C 1 ATOM 1552 O O . ALA A 1 212 ? 15.725 11.226 -5.327 1.00 24.61 ? 212 ALA A O 1 ATOM 1553 C CB . ALA A 1 212 ? 16.226 8.777 -7.502 1.00 22.58 ? 212 ALA A CB 1 ATOM 1554 N N . VAL A 1 213 ? 15.013 9.208 -4.621 1.00 22.95 ? 213 VAL A N 1 ATOM 1555 C CA . VAL A 1 213 ? 14.035 9.789 -3.706 1.00 22.44 ? 213 VAL A CA 1 ATOM 1556 C C . VAL A 1 213 ? 14.742 10.564 -2.602 1.00 24.73 ? 213 VAL A C 1 ATOM 1557 O O . VAL A 1 213 ? 14.335 11.674 -2.239 1.00 24.06 ? 213 VAL A O 1 ATOM 1558 C CB . VAL A 1 213 ? 13.116 8.688 -3.143 1.00 25.35 ? 213 VAL A CB 1 ATOM 1559 C CG1 . VAL A 1 213 ? 12.280 9.226 -1.980 1.00 22.43 ? 213 VAL A CG1 1 ATOM 1560 C CG2 . VAL A 1 213 ? 12.217 8.142 -4.236 1.00 23.02 ? 213 VAL A CG2 1 ATOM 1561 N N . ASP A 1 214 ? 15.833 10.011 -2.072 1.00 22.98 ? 214 ASP A N 1 ATOM 1562 C CA . ASP A 1 214 ? 16.541 10.696 -1.001 1.00 24.28 ? 214 ASP A CA 1 ATOM 1563 C C . ASP A 1 214 ? 17.022 12.074 -1.449 1.00 24.84 ? 214 ASP A C 1 ATOM 1564 O O . ASP A 1 214 ? 16.970 13.043 -0.681 1.00 25.06 ? 214 ASP A O 1 ATOM 1565 C CB . ASP A 1 214 ? 17.716 9.841 -0.526 1.00 23.04 ? 214 ASP A CB 1 ATOM 1566 C CG . ASP A 1 214 ? 18.464 10.480 0.626 1.00 26.27 ? 214 ASP A CG 1 ATOM 1567 O OD1 . ASP A 1 214 ? 18.042 10.304 1.786 1.00 29.92 ? 214 ASP A OD1 1 ATOM 1568 O OD2 . ASP A 1 214 ? 19.463 11.183 0.379 1.00 31.95 ? 214 ASP A OD2 1 ATOM 1569 N N . THR A 1 215 ? 17.475 12.182 -2.695 1.00 20.48 ? 215 THR A N 1 ATOM 1570 C CA . THR A 1 215 ? 17.955 13.466 -3.191 1.00 26.54 ? 215 THR A CA 1 ATOM 1571 C C . THR A 1 215 ? 16.807 14.449 -3.369 1.00 26.15 ? 215 THR A C 1 ATOM 1572 O O . THR A 1 215 ? 16.945 15.632 -3.044 1.00 25.64 ? 215 THR A O 1 ATOM 1573 C CB . THR A 1 215 ? 18.715 13.254 -4.497 1.00 26.74 ? 215 THR A CB 1 ATOM 1574 O OG1 . THR A 1 215 ? 19.795 12.345 -4.248 1.00 29.56 ? 215 THR A OG1 1 ATOM 1575 C CG2 . THR A 1 215 ? 19.274 14.565 -5.030 1.00 31.47 ? 215 THR A CG2 1 ATOM 1576 N N . VAL A 1 216 ? 15.657 13.975 -3.857 1.00 24.43 ? 216 VAL A N 1 ATOM 1577 C CA . VAL A 1 216 ? 14.491 14.853 -3.958 1.00 24.51 ? 216 VAL A CA 1 ATOM 1578 C C . VAL A 1 216 ? 14.089 15.373 -2.578 1.00 24.96 ? 216 VAL A C 1 ATOM 1579 O O . VAL A 1 216 ? 13.731 16.546 -2.427 1.00 24.61 ? 216 VAL A O 1 ATOM 1580 C CB . VAL A 1 216 ? 13.319 14.133 -4.659 1.00 22.17 ? 216 VAL A CB 1 ATOM 1581 C CG1 . VAL A 1 216 ? 12.054 15.003 -4.642 1.00 23.86 ? 216 VAL A CG1 1 ATOM 1582 C CG2 . VAL A 1 216 ? 13.675 13.817 -6.095 1.00 26.81 ? 216 VAL A CG2 1 ATOM 1583 N N . LEU A 1 217 ? 14.130 14.511 -1.553 1.00 24.35 ? 217 LEU A N 1 ATOM 1584 C CA . LEU A 1 217 ? 13.717 14.939 -0.212 1.00 24.13 ? 217 LEU A CA 1 ATOM 1585 C C . LEU A 1 217 ? 14.678 15.967 0.371 1.00 27.62 ? 217 LEU A C 1 ATOM 1586 O O . LEU A 1 217 ? 14.251 16.910 1.052 1.00 25.31 ? 217 LEU A O 1 ATOM 1587 C CB . LEU A 1 217 ? 13.609 13.737 0.727 1.00 25.03 ? 217 LEU A CB 1 ATOM 1588 C CG . LEU A 1 217 ? 12.588 12.683 0.311 1.00 25.73 ? 217 LEU A CG 1 ATOM 1589 C CD1 . LEU A 1 217 ? 12.560 11.545 1.317 1.00 25.66 ? 217 LEU A CD1 1 ATOM 1590 C CD2 . LEU A 1 217 ? 11.204 13.321 0.167 1.00 22.20 ? 217 LEU A CD2 1 ATOM 1591 N N . LYS A 1 218 ? 15.977 15.789 0.122 1.00 27.45 ? 218 LYS A N 1 ATOM 1592 C CA . LYS A 1 218 ? 16.978 16.768 0.533 1.00 28.69 ? 218 LYS A CA 1 ATOM 1593 C C . LYS A 1 218 ? 16.644 18.155 0.000 1.00 28.43 ? 218 LYS A C 1 ATOM 1594 O O . LYS A 1 218 ? 16.651 19.143 0.747 1.00 32.52 ? 218 LYS A O 1 ATOM 1595 C CB . LYS A 1 218 ? 18.354 16.327 0.035 1.00 28.64 ? 218 LYS A CB 1 ATOM 1596 C CG . LYS A 1 218 ? 19.435 17.377 0.197 1.00 36.88 ? 218 LYS A CG 1 ATOM 1597 C CD . LYS A 1 218 ? 20.492 16.910 1.175 1.00 45.71 ? 218 LYS A CD 1 ATOM 1598 C CE . LYS A 1 218 ? 21.245 18.093 1.792 1.00 53.50 ? 218 LYS A CE 1 ATOM 1599 N NZ . LYS A 1 218 ? 21.808 17.785 3.143 1.00 41.20 ? 218 LYS A NZ 1 ATOM 1600 N N . TYR A 1 219 ? 16.346 18.251 -1.296 1.00 26.65 ? 219 TYR A N 1 ATOM 1601 C CA . TYR A 1 219 ? 16.039 19.561 -1.864 1.00 27.14 ? 219 TYR A CA 1 ATOM 1602 C C . TYR A 1 219 ? 14.625 20.010 -1.538 1.00 30.87 ? 219 TYR A C 1 ATOM 1603 O O . TYR A 1 219 ? 14.385 21.220 -1.412 1.00 30.69 ? 219 TYR A O 1 ATOM 1604 C CB . TYR A 1 219 ? 16.310 19.552 -3.367 1.00 28.24 ? 219 TYR A CB 1 ATOM 1605 C CG . TYR A 1 219 ? 17.801 19.559 -3.617 1.00 29.66 ? 219 TYR A CG 1 ATOM 1606 C CD1 . TYR A 1 219 ? 18.550 20.716 -3.426 1.00 36.45 ? 219 TYR A CD1 1 ATOM 1607 C CD2 . TYR A 1 219 ? 18.470 18.398 -3.987 1.00 29.99 ? 219 TYR A CD2 1 ATOM 1608 C CE1 . TYR A 1 219 ? 19.923 20.721 -3.626 1.00 34.66 ? 219 TYR A CE1 1 ATOM 1609 C CE2 . TYR A 1 219 ? 19.837 18.394 -4.187 1.00 36.48 ? 219 TYR A CE2 1 ATOM 1610 C CZ . TYR A 1 219 ? 20.559 19.554 -4.000 1.00 39.24 ? 219 TYR A CZ 1 ATOM 1611 O OH . TYR A 1 219 ? 21.925 19.545 -4.196 1.00 45.27 ? 219 TYR A OH 1 ATOM 1612 N N . MET A 1 220 ? 13.695 19.067 -1.349 1.00 25.04 ? 220 MET A N 1 ATOM 1613 C CA . MET A 1 220 ? 12.371 19.422 -0.845 1.00 25.44 ? 220 MET A CA 1 ATOM 1614 C C . MET A 1 220 ? 12.463 20.214 0.447 1.00 27.91 ? 220 MET A C 1 ATOM 1615 O O . MET A 1 220 ? 11.725 21.186 0.642 1.00 24.46 ? 220 MET A O 1 ATOM 1616 C CB . MET A 1 220 ? 11.523 18.175 -0.606 1.00 24.20 ? 220 MET A CB 1 ATOM 1617 C CG . MET A 1 220 ? 10.177 18.484 0.066 1.00 26.12 ? 220 MET A CG 1 ATOM 1618 S SD . MET A 1 220 ? 9.311 17.036 0.721 1.00 27.51 ? 220 MET A SD 1 ATOM 1619 C CE . MET A 1 220 ? 10.322 16.674 2.147 1.00 25.73 ? 220 MET A CE 1 ATOM 1620 N N . ILE A 1 221 ? 13.357 19.803 1.351 1.00 25.07 ? 221 ILE A N 1 ATOM 1621 C CA . ILE A 1 221 ? 13.539 20.543 2.595 1.00 26.85 ? 221 ILE A CA 1 ATOM 1622 C C . ILE A 1 221 ? 14.004 21.962 2.294 1.00 30.56 ? 221 ILE A C 1 ATOM 1623 O O . ILE A 1 221 ? 13.555 22.927 2.928 1.00 29.73 ? 221 ILE A O 1 ATOM 1624 C CB . ILE A 1 221 ? 14.528 19.803 3.516 1.00 28.00 ? 221 ILE A CB 1 ATOM 1625 C CG1 . ILE A 1 221 ? 13.944 18.463 3.978 1.00 28.67 ? 221 ILE A CG1 1 ATOM 1626 C CG2 . ILE A 1 221 ? 14.890 20.655 4.737 1.00 30.18 ? 221 ILE A CG2 1 ATOM 1627 C CD1 . ILE A 1 221 ? 15.012 17.479 4.445 1.00 36.35 ? 221 ILE A CD1 1 ATOM 1628 N N . GLN A 1 222 ? 14.916 22.108 1.325 1.00 26.75 ? 222 GLN A N 1 ATOM 1629 C CA . GLN A 1 222 ? 15.369 23.440 0.931 1.00 31.41 ? 222 GLN A CA 1 ATOM 1630 C C . GLN A 1 222 ? 14.237 24.249 0.319 1.00 31.53 ? 222 GLN A C 1 ATOM 1631 O O . GLN A 1 222 ? 14.101 25.447 0.600 1.00 31.49 ? 222 GLN A O 1 ATOM 1632 C CB . GLN A 1 222 ? 16.534 23.336 -0.055 1.00 34.55 ? 222 GLN A CB 1 ATOM 1633 C CG . GLN A 1 222 ? 17.828 22.878 0.578 1.00 37.30 ? 222 GLN A CG 1 ATOM 1634 C CD . GLN A 1 222 ? 18.286 23.807 1.690 1.00 44.37 ? 222 GLN A CD 1 ATOM 1635 O OE1 . GLN A 1 222 ? 18.396 25.019 1.500 1.00 42.15 ? 222 GLN A OE1 1 ATOM 1636 N NE2 . GLN A 1 222 ? 18.536 23.239 2.864 1.00 44.05 ? 222 GLN A NE2 1 ATOM 1637 N N . TRP A 1 223 ? 13.428 23.620 -0.539 1.00 27.72 ? 223 TRP A N 1 ATOM 1638 C CA . TRP A 1 223 ? 12.319 24.338 -1.165 1.00 28.25 ? 223 TRP A CA 1 ATOM 1639 C C . TRP A 1 223 ? 11.321 24.819 -0.121 1.00 28.57 ? 223 TRP A C 1 ATOM 1640 O O . TRP A 1 223 ? 10.770 25.919 -0.244 1.00 31.49 ? 223 TRP A O 1 ATOM 1641 C CB . TRP A 1 223 ? 11.609 23.453 -2.197 1.00 28.67 ? 223 TRP A CB 1 ATOM 1642 C CG . TRP A 1 223 ? 12.483 22.872 -3.280 1.00 31.76 ? 223 TRP A CG 1 ATOM 1643 C CD1 . TRP A 1 223 ? 13.717 23.315 -3.685 1.00 30.54 ? 223 TRP A CD1 1 ATOM 1644 C CD2 . TRP A 1 223 ? 12.186 21.725 -4.089 1.00 28.19 ? 223 TRP A CD2 1 ATOM 1645 N NE1 . TRP A 1 223 ? 14.199 22.512 -4.694 1.00 30.57 ? 223 TRP A NE1 1 ATOM 1646 C CE2 . TRP A 1 223 ? 13.280 21.531 -4.961 1.00 29.24 ? 223 TRP A CE2 1 ATOM 1647 C CE3 . TRP A 1 223 ? 11.101 20.847 -4.161 1.00 26.61 ? 223 TRP A CE3 1 ATOM 1648 C CZ2 . TRP A 1 223 ? 13.322 20.489 -5.885 1.00 30.04 ? 223 TRP A CZ2 1 ATOM 1649 C CZ3 . TRP A 1 223 ? 11.139 19.816 -5.088 1.00 26.35 ? 223 TRP A CZ3 1 ATOM 1650 C CH2 . TRP A 1 223 ? 12.245 19.647 -5.935 1.00 30.12 ? 223 TRP A CH2 1 ATOM 1651 N N . ILE A 1 224 ? 11.066 24.002 0.907 1.00 25.86 ? 224 ILE A N 1 ATOM 1652 C CA . ILE A 1 224 ? 10.119 24.382 1.955 1.00 28.29 ? 224 ILE A CA 1 ATOM 1653 C C . ILE A 1 224 ? 10.603 25.633 2.675 1.00 32.59 ? 224 ILE A C 1 ATOM 1654 O O . ILE A 1 224 ? 9.862 26.613 2.832 1.00 30.36 ? 224 ILE A O 1 ATOM 1655 C CB . ILE A 1 224 ? 9.916 23.216 2.937 1.00 23.13 ? 224 ILE A CB 1 ATOM 1656 C CG1 . ILE A 1 224 ? 9.147 22.072 2.257 1.00 24.74 ? 224 ILE A CG1 1 ATOM 1657 C CG2 . ILE A 1 224 ? 9.188 23.689 4.195 1.00 27.22 ? 224 ILE A CG2 1 ATOM 1658 C CD1 . ILE A 1 224 ? 9.082 20.811 3.095 1.00 26.31 ? 224 ILE A CD1 1 ATOM 1659 N N . GLN A 1 225 ? 11.858 25.612 3.121 1.00 30.21 ? 225 GLN A N 1 ATOM 1660 C CA . GLN A 1 225 ? 12.452 26.784 3.755 1.00 31.87 ? 225 GLN A CA 1 ATOM 1661 C C . GLN A 1 225 ? 12.481 27.975 2.799 1.00 31.30 ? 225 GLN A C 1 ATOM 1662 O O . GLN A 1 225 ? 12.059 29.083 3.154 1.00 33.42 ? 225 GLN A O 1 ATOM 1663 C CB . GLN A 1 225 ? 13.857 26.430 4.246 1.00 33.87 ? 225 GLN A CB 1 ATOM 1664 C CG . GLN A 1 225 ? 13.843 25.531 5.474 1.00 47.12 ? 225 GLN A CG 1 ATOM 1665 C CD . GLN A 1 225 ? 15.104 24.694 5.646 1.00 48.57 ? 225 GLN A CD 1 ATOM 1666 O OE1 . GLN A 1 225 ? 16.015 24.720 4.813 1.00 50.61 ? 225 GLN A OE1 1 ATOM 1667 N NE2 . GLN A 1 225 ? 15.156 23.938 6.737 1.00 47.91 ? 225 GLN A NE2 1 ATOM 1668 N N . ASP A 1 226 ? 12.943 27.755 1.566 1.00 26.12 ? 226 ASP A N 1 ATOM 1669 C CA . ASP A 1 226 ? 13.168 28.870 0.653 1.00 32.80 ? 226 ASP A CA 1 ATOM 1670 C C . ASP A 1 226 ? 11.871 29.562 0.266 1.00 36.12 ? 226 ASP A C 1 ATOM 1671 O O . ASP A 1 226 ? 11.873 30.775 0.019 1.00 33.02 ? 226 ASP A O 1 ATOM 1672 C CB . ASP A 1 226 ? 13.898 28.400 -0.605 1.00 31.74 ? 226 ASP A CB 1 ATOM 1673 C CG . ASP A 1 226 ? 15.336 28.014 -0.338 1.00 34.23 ? 226 ASP A CG 1 ATOM 1674 O OD1 . ASP A 1 226 ? 15.810 28.183 0.807 1.00 40.64 ? 226 ASP A OD1 1 ATOM 1675 O OD2 . ASP A 1 226 ? 16.003 27.541 -1.280 1.00 39.67 ? 226 ASP A OD2 1 ATOM 1676 N N . ARG A 1 227 ? 10.760 28.821 0.201 1.00 29.35 ? 227 ARG A N 1 ATOM 1677 C CA . ARG A 1 227 ? 9.466 29.394 -0.150 1.00 29.83 ? 227 ARG A CA 1 ATOM 1678 C C . ARG A 1 227 ? 8.682 29.883 1.061 1.00 33.27 ? 227 ARG A C 1 ATOM 1679 O O . ARG A 1 227 ? 7.529 30.300 0.907 1.00 34.22 ? 227 ARG A O 1 ATOM 1680 C CB . ARG A 1 227 ? 8.631 28.381 -0.937 1.00 30.18 ? 227 ARG A CB 1 ATOM 1681 C CG . ARG A 1 227 ? 9.332 27.934 -2.190 1.00 31.05 ? 227 ARG A CG 1 ATOM 1682 C CD . ARG A 1 227 ? 8.581 26.826 -2.913 1.00 31.13 ? 227 ARG A CD 1 ATOM 1683 N NE . ARG A 1 227 ? 9.487 26.139 -3.822 1.00 31.69 ? 227 ARG A NE 1 ATOM 1684 C CZ . ARG A 1 227 ? 9.101 25.282 -4.755 1.00 35.27 ? 227 ARG A CZ 1 ATOM 1685 N NH1 . ARG A 1 227 ? 7.814 25.009 -4.905 1.00 32.19 ? 227 ARG A NH1 1 ATOM 1686 N NH2 . ARG A 1 227 ? 10.007 24.704 -5.533 1.00 35.93 ? 227 ARG A NH2 1 ATOM 1687 N N . GLY A 1 228 ? 9.273 29.840 2.252 1.00 30.72 ? 228 GLY A N 1 ATOM 1688 C CA . GLY A 1 228 ? 8.650 30.441 3.413 1.00 35.47 ? 228 GLY A CA 1 ATOM 1689 C C . GLY A 1 228 ? 7.600 29.599 4.086 1.00 41.24 ? 228 GLY A C 1 ATOM 1690 O O . GLY A 1 228 ? 6.749 30.147 4.793 1.00 37.05 ? 228 GLY A O 1 ATOM 1691 N N . LEU A 1 229 ? 7.639 28.277 3.897 1.00 33.12 ? 229 LEU A N 1 ATOM 1692 C CA . LEU A 1 229 ? 6.629 27.361 4.408 1.00 32.17 ? 229 LEU A CA 1 ATOM 1693 C C . LEU A 1 229 ? 7.047 26.634 5.680 1.00 29.79 ? 229 LEU A C 1 ATOM 1694 O O . LEU A 1 229 ? 6.234 25.893 6.238 1.00 32.40 ? 229 LEU A O 1 ATOM 1695 C CB . LEU A 1 229 ? 6.279 26.310 3.339 1.00 33.23 ? 229 LEU A CB 1 ATOM 1696 C CG . LEU A 1 229 ? 5.521 26.771 2.101 1.00 38.97 ? 229 LEU A CG 1 ATOM 1697 C CD1 . LEU A 1 229 ? 5.441 25.671 1.047 1.00 32.00 ? 229 LEU A CD1 1 ATOM 1698 C CD2 . LEU A 1 229 ? 4.135 27.222 2.515 1.00 38.11 ? 229 LEU A CD2 1 ATOM 1699 N N . GLN A 1 230 ? 8.282 26.823 6.155 1.00 30.46 ? 230 GLN A N 1 ATOM 1700 C CA . GLN A 1 230 ? 8.797 25.951 7.203 1.00 32.46 ? 230 GLN A CA 1 ATOM 1701 C C . GLN A 1 230 ? 7.917 25.957 8.448 1.00 36.34 ? 230 GLN A C 1 ATOM 1702 O O . GLN A 1 230 ? 7.778 24.922 9.107 1.00 37.55 ? 230 GLN A O 1 ATOM 1703 C CB . GLN A 1 230 ? 10.232 26.336 7.564 1.00 46.13 ? 230 GLN A CB 1 ATOM 1704 C CG . GLN A 1 230 ? 10.888 25.348 8.519 1.00 46.14 ? 230 GLN A CG 1 ATOM 1705 C CD . GLN A 1 230 ? 12.333 25.678 8.805 1.00 55.22 ? 230 GLN A CD 1 ATOM 1706 O OE1 . GLN A 1 230 ? 12.873 26.656 8.288 1.00 56.47 ? 230 GLN A OE1 1 ATOM 1707 N NE2 . GLN A 1 230 ? 12.972 24.861 9.634 1.00 61.05 ? 230 GLN A NE2 1 ATOM 1708 N N . GLN A 1 231 ? 7.291 27.088 8.775 1.00 36.59 ? 231 GLN A N 1 ATOM 1709 C CA . GLN A 1 231 ? 6.447 27.153 9.962 1.00 37.04 ? 231 GLN A CA 1 ATOM 1710 C C . GLN A 1 231 ? 4.981 26.852 9.677 1.00 38.32 ? 231 GLN A C 1 ATOM 1711 O O . GLN A 1 231 ? 4.187 26.777 10.622 1.00 35.86 ? 231 GLN A O 1 ATOM 1712 C CB . GLN A 1 231 ? 6.568 28.533 10.623 1.00 47.51 ? 231 GLN A CB 1 ATOM 1713 C CG . GLN A 1 231 ? 7.951 28.807 11.177 1.00 42.47 ? 231 GLN A CG 1 ATOM 1714 C CD . GLN A 1 231 ? 8.447 27.676 12.055 1.00 55.61 ? 231 GLN A CD 1 ATOM 1715 O OE1 . GLN A 1 231 ? 7.726 27.200 12.937 1.00 61.49 ? 231 GLN A OE1 1 ATOM 1716 N NE2 . GLN A 1 231 ? 9.677 27.226 11.809 1.00 55.44 ? 231 GLN A NE2 1 ATOM 1717 N N . ASP A 1 232 ? 4.609 26.672 8.410 1.00 34.25 ? 232 ASP A N 1 ATOM 1718 C CA . ASP A 1 232 ? 3.220 26.499 8.014 1.00 36.19 ? 232 ASP A CA 1 ATOM 1719 C C . ASP A 1 232 ? 2.889 25.093 7.529 1.00 33.58 ? 232 ASP A C 1 ATOM 1720 O O . ASP A 1 232 ? 1.754 24.863 7.107 1.00 33.32 ? 232 ASP A O 1 ATOM 1721 C CB . ASP A 1 232 ? 2.857 27.491 6.904 1.00 35.26 ? 232 ASP A CB 1 ATOM 1722 C CG . ASP A 1 232 ? 2.921 28.932 7.361 1.00 52.19 ? 232 ASP A CG 1 ATOM 1723 O OD1 . ASP A 1 232 ? 2.743 29.192 8.572 1.00 54.21 ? 232 ASP A OD1 1 ATOM 1724 O OD2 . ASP A 1 232 ? 3.149 29.805 6.499 1.00 58.15 ? 232 ASP A OD2 1 ATOM 1725 N N . LEU A 1 233 ? 3.830 24.150 7.581 1.00 31.88 ? 233 LEU A N 1 ATOM 1726 C CA . LEU A 1 233 ? 3.697 22.897 6.837 1.00 25.73 ? 233 LEU A CA 1 ATOM 1727 C C . LEU A 1 233 ? 4.269 21.733 7.633 1.00 30.87 ? 233 LEU A C 1 ATOM 1728 O O . LEU A 1 233 ? 5.438 21.772 8.025 1.00 30.91 ? 233 LEU A O 1 ATOM 1729 C CB . LEU A 1 233 ? 4.420 23.017 5.491 1.00 28.73 ? 233 LEU A CB 1 ATOM 1730 C CG . LEU A 1 233 ? 4.495 21.733 4.668 1.00 24.21 ? 233 LEU A CG 1 ATOM 1731 C CD1 . LEU A 1 233 ? 3.095 21.311 4.295 1.00 27.96 ? 233 LEU A CD1 1 ATOM 1732 C CD2 . LEU A 1 233 ? 5.360 21.928 3.419 1.00 30.01 ? 233 LEU A CD2 1 ATOM 1733 N N . ASN A 1 234 ? 3.467 20.689 7.846 1.00 23.31 ? 234 ASN A N 1 ATOM 1734 C CA . ASN A 1 234 ? 4.001 19.398 8.267 1.00 24.26 ? 234 ASN A CA 1 ATOM 1735 C C . ASN A 1 234 ? 4.126 18.485 7.054 1.00 21.75 ? 234 ASN A C 1 ATOM 1736 O O . ASN A 1 234 ? 3.366 18.595 6.091 1.00 22.67 ? 234 ASN A O 1 ATOM 1737 C CB . ASN A 1 234 ? 3.116 18.723 9.316 1.00 21.74 ? 234 ASN A CB 1 ATOM 1738 C CG . ASN A 1 234 ? 3.071 19.487 10.629 1.00 29.57 ? 234 ASN A CG 1 ATOM 1739 O OD1 . ASN A 1 234 ? 4.100 19.743 11.253 1.00 29.06 ? 234 ASN A OD1 1 ATOM 1740 N ND2 . ASN A 1 234 ? 1.868 19.846 11.060 1.00 31.54 ? 234 ASN A ND2 1 ATOM 1741 N N . VAL A 1 235 ? 5.107 17.589 7.101 1.00 21.17 ? 235 VAL A N 1 ATOM 1742 C CA . VAL A 1 235 ? 5.305 16.600 6.047 1.00 20.36 ? 235 VAL A CA 1 ATOM 1743 C C . VAL A 1 235 ? 5.277 15.222 6.697 1.00 24.95 ? 235 VAL A C 1 ATOM 1744 O O . VAL A 1 235 ? 5.993 14.968 7.672 1.00 21.90 ? 235 VAL A O 1 ATOM 1745 C CB . VAL A 1 235 ? 6.626 16.816 5.281 1.00 24.53 ? 235 VAL A CB 1 ATOM 1746 C CG1 . VAL A 1 235 ? 6.768 15.788 4.152 1.00 24.25 ? 235 VAL A CG1 1 ATOM 1747 C CG2 . VAL A 1 235 ? 6.692 18.227 4.721 1.00 25.29 ? 235 VAL A CG2 1 ATOM 1748 N N . ILE A 1 236 ? 4.443 14.337 6.171 1.00 19.33 ? 236 ILE A N 1 ATOM 1749 C CA . ILE A 1 236 ? 4.356 12.975 6.669 1.00 18.90 ? 236 ILE A CA 1 ATOM 1750 C C . ILE A 1 236 ? 4.723 12.057 5.515 1.00 19.58 ? 236 ILE A C 1 ATOM 1751 O O . ILE A 1 236 ? 4.291 12.281 4.380 1.00 20.65 ? 236 ILE A O 1 ATOM 1752 C CB . ILE A 1 236 ? 2.955 12.673 7.242 1.00 23.83 ? 236 ILE A CB 1 ATOM 1753 C CG1 . ILE A 1 236 ? 2.790 13.341 8.616 1.00 20.78 ? 236 ILE A CG1 1 ATOM 1754 C CG2 . ILE A 1 236 ? 2.687 11.154 7.333 1.00 17.80 ? 236 ILE A CG2 1 ATOM 1755 C CD1 . ILE A 1 236 ? 1.343 13.335 9.150 1.00 25.30 ? 236 ILE A CD1 1 ATOM 1756 N N . LEU A 1 237 ? 5.570 11.065 5.791 1.00 19.67 ? 237 LEU A N 1 ATOM 1757 C CA . LEU A 1 237 ? 6.006 10.102 4.790 1.00 19.48 ? 237 LEU A CA 1 ATOM 1758 C C . LEU A 1 237 ? 5.757 8.706 5.340 1.00 19.58 ? 237 LEU A C 1 ATOM 1759 O O . LEU A 1 237 ? 6.102 8.430 6.491 1.00 20.68 ? 237 LEU A O 1 ATOM 1760 C CB . LEU A 1 237 ? 7.505 10.261 4.463 1.00 22.92 ? 237 LEU A CB 1 ATOM 1761 C CG . LEU A 1 237 ? 8.091 11.609 4.029 1.00 26.97 ? 237 LEU A CG 1 ATOM 1762 C CD1 . LEU A 1 237 ? 8.387 12.520 5.235 1.00 27.85 ? 237 LEU A CD1 1 ATOM 1763 C CD2 . LEU A 1 237 ? 9.339 11.381 3.191 1.00 30.11 ? 237 LEU A CD2 1 ATOM 1764 N N . PHE A 1 238 ? 5.189 7.822 4.522 1.00 17.78 ? 238 PHE A N 1 ATOM 1765 C CA . PHE A 1 238 ? 5.020 6.436 4.944 1.00 17.62 ? 238 PHE A CA 1 ATOM 1766 C C . PHE A 1 238 ? 4.977 5.544 3.714 1.00 17.19 ? 238 PHE A C 1 ATOM 1767 O O . PHE A 1 238 ? 4.981 6.021 2.576 1.00 17.07 ? 238 PHE A O 1 ATOM 1768 C CB . PHE A 1 238 ? 3.757 6.241 5.794 1.00 15.81 ? 238 PHE A CB 1 ATOM 1769 C CG . PHE A 1 238 ? 2.531 6.901 5.229 1.00 19.09 ? 238 PHE A CG 1 ATOM 1770 C CD1 . PHE A 1 238 ? 1.944 6.440 4.061 1.00 18.10 ? 238 PHE A CD1 1 ATOM 1771 C CD2 . PHE A 1 238 ? 1.959 7.974 5.889 1.00 22.15 ? 238 PHE A CD2 1 ATOM 1772 C CE1 . PHE A 1 238 ? 0.816 7.052 3.542 1.00 18.30 ? 238 PHE A CE1 1 ATOM 1773 C CE2 . PHE A 1 238 ? 0.827 8.595 5.386 1.00 19.14 ? 238 PHE A CE2 1 ATOM 1774 C CZ . PHE A 1 238 ? 0.253 8.126 4.213 1.00 20.12 ? 238 PHE A CZ 1 ATOM 1775 N N . SER A 1 239 ? 4.936 4.236 3.959 1.00 16.98 ? 239 SER A N 1 ATOM 1776 C CA . SER A 1 239 ? 4.807 3.258 2.889 1.00 18.23 ? 239 SER A CA 1 ATOM 1777 C C . SER A 1 239 ? 3.686 2.285 3.193 1.00 18.85 ? 239 SER A C 1 ATOM 1778 O O . SER A 1 239 ? 3.217 2.174 4.330 1.00 18.87 ? 239 SER A O 1 ATOM 1779 C CB . SER A 1 239 ? 6.103 2.473 2.652 1.00 16.11 ? 239 SER A CB 1 ATOM 1780 O OG . SER A 1 239 ? 6.490 1.713 3.788 1.00 18.09 ? 239 SER A OG 1 ATOM 1781 N N . ASP A 1 240 ? 3.268 1.577 2.138 1.00 16.26 ? 240 ASP A N 1 ATOM 1782 C CA . ASP A 1 240 ? 2.183 0.624 2.236 1.00 15.10 ? 240 ASP A CA 1 ATOM 1783 C C . ASP A 1 240 ? 2.633 -0.764 2.687 1.00 16.31 ? 240 ASP A C 1 ATOM 1784 O O . ASP A 1 240 ? 1.811 -1.499 3.239 1.00 17.93 ? 240 ASP A O 1 ATOM 1785 C CB . ASP A 1 240 ? 1.422 0.532 0.897 1.00 15.54 ? 240 ASP A CB 1 ATOM 1786 C CG . ASP A 1 240 ? 2.314 0.212 -0.315 1.00 19.89 ? 240 ASP A CG 1 ATOM 1787 O OD1 . ASP A 1 240 ? 3.559 0.365 -0.272 1.00 19.13 ? 240 ASP A OD1 1 ATOM 1788 O OD2 . ASP A 1 240 ? 1.734 -0.220 -1.338 1.00 18.91 ? 240 ASP A OD2 1 ATOM 1789 N N . HIS A 1 241 ? 3.909 -1.116 2.506 1.00 17.44 ? 241 HIS A N 1 ATOM 1790 C CA . HIS A 1 241 ? 4.430 -2.438 2.871 1.00 18.69 ? 241 HIS A CA 1 ATOM 1791 C C . HIS A 1 241 ? 5.910 -2.475 2.507 1.00 18.47 ? 241 HIS A C 1 ATOM 1792 O O . HIS A 1 241 ? 6.424 -1.580 1.830 1.00 18.37 ? 241 HIS A O 1 ATOM 1793 C CB . HIS A 1 241 ? 3.694 -3.549 2.123 1.00 18.89 ? 241 HIS A CB 1 ATOM 1794 C CG . HIS A 1 241 ? 3.708 -3.335 0.646 1.00 14.46 ? 241 HIS A CG 1 ATOM 1795 N ND1 . HIS A 1 241 ? 4.857 -3.455 -0.105 1.00 17.91 ? 241 HIS A ND1 1 ATOM 1796 C CD2 . HIS A 1 241 ? 2.753 -2.884 -0.199 1.00 17.57 ? 241 HIS A CD2 1 ATOM 1797 C CE1 . HIS A 1 241 ? 4.598 -3.118 -1.356 1.00 20.80 ? 241 HIS A CE1 1 ATOM 1798 N NE2 . HIS A 1 241 ? 3.327 -2.776 -1.440 1.00 18.20 ? 241 HIS A NE2 1 ATOM 1799 N N . GLY A 1 242 ? 6.579 -3.544 2.921 1.00 18.77 ? 242 GLY A N 1 ATOM 1800 C CA . GLY A 1 242 ? 7.984 -3.783 2.572 1.00 20.86 ? 242 GLY A CA 1 ATOM 1801 C C . GLY A 1 242 ? 8.147 -4.677 1.350 1.00 19.86 ? 242 GLY A C 1 ATOM 1802 O O . GLY A 1 242 ? 7.403 -4.577 0.365 1.00 19.30 ? 242 GLY A O 1 ATOM 1803 N N . MET A 1 243 ? 9.152 -5.558 1.395 1.00 20.22 ? 243 MET A N 1 ATOM 1804 C CA . MET A 1 243 ? 9.497 -6.321 0.199 1.00 16.80 ? 243 MET A CA 1 ATOM 1805 C C . MET A 1 243 ? 10.398 -7.473 0.624 1.00 19.61 ? 243 MET A C 1 ATOM 1806 O O . MET A 1 243 ? 11.220 -7.292 1.514 1.00 20.22 ? 243 MET A O 1 ATOM 1807 C CB . MET A 1 243 ? 10.209 -5.424 -0.831 1.00 18.85 ? 243 MET A CB 1 ATOM 1808 C CG . MET A 1 243 ? 10.547 -6.091 -2.189 1.00 21.98 ? 243 MET A CG 1 ATOM 1809 S SD . MET A 1 243 ? 9.150 -6.352 -3.298 1.00 21.39 ? 243 MET A SD 1 ATOM 1810 C CE . MET A 1 243 ? 8.678 -4.653 -3.646 1.00 16.93 ? 243 MET A CE 1 ATOM 1811 N N . THR A 1 244 ? 10.223 -8.649 0.008 1.00 18.70 ? 244 THR A N 1 ATOM 1812 C CA . THR A 1 244 ? 11.053 -9.808 0.348 1.00 21.61 ? 244 THR A CA 1 ATOM 1813 C C . THR A 1 244 ? 11.529 -10.512 -0.924 1.00 23.66 ? 244 THR A C 1 ATOM 1814 O O . THR A 1 244 ? 11.031 -10.274 -2.022 1.00 21.68 ? 244 THR A O 1 ATOM 1815 C CB . THR A 1 244 ? 10.318 -10.807 1.273 1.00 21.93 ? 244 THR A CB 1 ATOM 1816 O OG1 . THR A 1 244 ? 11.265 -11.727 1.857 1.00 24.98 ? 244 THR A OG1 1 ATOM 1817 C CG2 . THR A 1 244 ? 9.298 -11.620 0.511 1.00 20.42 ? 244 THR A CG2 1 ATOM 1818 N N . ASP A 1 245 ? 12.539 -11.371 -0.776 1.00 20.26 ? 245 ASP A N 1 ATOM 1819 C CA . ASP A 1 245 ? 13.013 -12.131 -1.926 1.00 24.57 ? 245 ASP A CA 1 ATOM 1820 C C . ASP A 1 245 ? 12.026 -13.227 -2.310 1.00 21.63 ? 245 ASP A C 1 ATOM 1821 O O . ASP A 1 245 ? 11.412 -13.864 -1.449 1.00 25.61 ? 245 ASP A O 1 ATOM 1822 C CB . ASP A 1 245 ? 14.369 -12.763 -1.620 1.00 24.19 ? 245 ASP A CB 1 ATOM 1823 C CG . ASP A 1 245 ? 15.439 -11.736 -1.374 1.00 28.56 ? 245 ASP A CG 1 ATOM 1824 O OD1 . ASP A 1 245 ? 15.738 -10.980 -2.307 1.00 25.21 ? 245 ASP A OD1 1 ATOM 1825 O OD2 . ASP A 1 245 ? 15.998 -11.697 -0.251 1.00 36.84 ? 245 ASP A OD2 1 ATOM 1826 N N . ILE A 1 246 ? 11.870 -13.443 -3.614 1.00 20.31 ? 246 ILE A N 1 ATOM 1827 C CA . ILE A 1 246 ? 11.180 -14.624 -4.111 1.00 22.76 ? 246 ILE A CA 1 ATOM 1828 C C . ILE A 1 246 ? 12.143 -15.404 -4.998 1.00 23.84 ? 246 ILE A C 1 ATOM 1829 O O . ILE A 1 246 ? 13.177 -14.894 -5.448 1.00 23.58 ? 246 ILE A O 1 ATOM 1830 C CB . ILE A 1 246 ? 9.878 -14.287 -4.860 1.00 22.50 ? 246 ILE A CB 1 ATOM 1831 C CG1 . ILE A 1 246 ? 10.125 -13.206 -5.914 1.00 21.57 ? 246 ILE A CG1 1 ATOM 1832 C CG2 . ILE A 1 246 ? 8.796 -13.886 -3.853 1.00 19.07 ? 246 ILE A CG2 1 ATOM 1833 C CD1 . ILE A 1 246 ? 8.935 -12.958 -6.816 1.00 23.32 ? 246 ILE A CD1 1 ATOM 1834 N N . PHE A 1 247 ? 11.782 -16.667 -5.259 1.00 27.25 ? 247 PHE A N 1 ATOM 1835 C CA . PHE A 1 247 ? 12.717 -17.643 -5.801 1.00 26.45 ? 247 PHE A CA 1 ATOM 1836 C C . PHE A 1 247 ? 12.046 -18.477 -6.894 1.00 27.36 ? 247 PHE A C 1 ATOM 1837 O O . PHE A 1 247 ? 11.775 -19.667 -6.726 1.00 34.17 ? 247 PHE A O 1 ATOM 1838 C CB . PHE A 1 247 ? 13.260 -18.533 -4.682 1.00 27.44 ? 247 PHE A CB 1 ATOM 1839 C CG . PHE A 1 247 ? 13.903 -17.765 -3.559 1.00 27.00 ? 247 PHE A CG 1 ATOM 1840 C CD1 . PHE A 1 247 ? 13.152 -17.336 -2.476 1.00 26.87 ? 247 PHE A CD1 1 ATOM 1841 C CD2 . PHE A 1 247 ? 15.259 -17.472 -3.593 1.00 27.74 ? 247 PHE A CD2 1 ATOM 1842 C CE1 . PHE A 1 247 ? 13.736 -16.622 -1.445 1.00 31.11 ? 247 PHE A CE1 1 ATOM 1843 C CE2 . PHE A 1 247 ? 15.859 -16.766 -2.558 1.00 30.12 ? 247 PHE A CE2 1 ATOM 1844 C CZ . PHE A 1 247 ? 15.097 -16.339 -1.484 1.00 33.10 ? 247 PHE A CZ 1 ATOM 1845 N N . TRP A 1 248 ? 11.763 -17.841 -8.021 1.00 29.12 ? 248 TRP A N 1 ATOM 1846 C CA . TRP A 1 248 ? 11.380 -18.553 -9.229 1.00 34.73 ? 248 TRP A CA 1 ATOM 1847 C C . TRP A 1 248 ? 12.628 -19.346 -9.663 1.00 37.18 ? 248 TRP A C 1 ATOM 1848 O O . TRP A 1 248 ? 13.740 -18.853 -9.510 1.00 39.81 ? 248 TRP A O 1 ATOM 1849 C CB . TRP A 1 248 ? 10.918 -17.584 -10.324 1.00 30.49 ? 248 TRP A CB 1 ATOM 1850 C CG . TRP A 1 248 ? 9.670 -16.759 -9.999 1.00 26.24 ? 248 TRP A CG 1 ATOM 1851 C CD1 . TRP A 1 248 ? 8.965 -16.762 -8.832 1.00 23.25 ? 248 TRP A CD1 1 ATOM 1852 C CD2 . TRP A 1 248 ? 9.001 -15.830 -10.870 1.00 25.72 ? 248 TRP A CD2 1 ATOM 1853 N NE1 . TRP A 1 248 ? 7.892 -15.901 -8.923 1.00 24.44 ? 248 TRP A NE1 1 ATOM 1854 C CE2 . TRP A 1 248 ? 7.900 -15.309 -10.159 1.00 25.99 ? 248 TRP A CE2 1 ATOM 1855 C CE3 . TRP A 1 248 ? 9.223 -15.396 -12.183 1.00 27.34 ? 248 TRP A CE3 1 ATOM 1856 C CZ2 . TRP A 1 248 ? 7.020 -14.381 -10.718 1.00 26.38 ? 248 TRP A CZ2 1 ATOM 1857 C CZ3 . TRP A 1 248 ? 8.351 -14.465 -12.737 1.00 29.69 ? 248 TRP A CZ3 1 ATOM 1858 C CH2 . TRP A 1 248 ? 7.260 -13.971 -12.003 1.00 28.86 ? 248 TRP A CH2 1 ATOM 1859 N N . MET A 1 249 ? 12.476 -20.568 -10.170 1.00 37.97 ? 249 MET A N 1 ATOM 1860 C CA . MET A 1 249 ? 11.203 -21.254 -10.307 1.00 34.17 ? 249 MET A CA 1 ATOM 1861 C C . MET A 1 249 ? 11.010 -22.286 -9.201 1.00 36.46 ? 249 MET A C 1 ATOM 1862 O O . MET A 1 249 ? 9.935 -22.875 -9.099 1.00 43.06 ? 249 MET A O 1 ATOM 1863 C CB . MET A 1 249 ? 11.117 -21.958 -11.668 1.00 44.75 ? 249 MET A CB 1 ATOM 1864 C CG . MET A 1 249 ? 11.164 -21.026 -12.865 1.00 42.83 ? 249 MET A CG 1 ATOM 1865 S SD . MET A 1 249 ? 9.603 -20.163 -13.049 1.00 44.34 ? 249 MET A SD 1 ATOM 1866 C CE . MET A 1 249 ? 10.054 -18.820 -14.159 1.00 42.64 ? 249 MET A CE 1 ATOM 1867 N N . ASP A 1 250 ? 12.056 -22.509 -8.392 1.00 35.82 ? 250 ASP A N 1 ATOM 1868 C CA . ASP A 1 250 ? 11.993 -23.532 -7.350 1.00 38.71 ? 250 ASP A CA 1 ATOM 1869 C C . ASP A 1 250 ? 10.781 -23.334 -6.451 1.00 39.11 ? 250 ASP A C 1 ATOM 1870 O O . ASP A 1 250 ? 10.061 -24.289 -6.142 1.00 33.42 ? 250 ASP A O 1 ATOM 1871 C CB . ASP A 1 250 ? 13.268 -23.524 -6.507 1.00 43.32 ? 250 ASP A CB 1 ATOM 1872 C CG . ASP A 1 250 ? 14.432 -24.179 -7.205 1.00 53.61 ? 250 ASP A CG 1 ATOM 1873 O OD1 . ASP A 1 250 ? 14.190 -24.960 -8.151 1.00 47.83 ? 250 ASP A OD1 1 ATOM 1874 O OD2 . ASP A 1 250 ? 15.588 -23.916 -6.804 1.00 60.45 ? 250 ASP A OD2 1 ATOM 1875 N N . LYS A 1 251 ? 10.536 -22.101 -6.020 1.00 30.69 ? 251 LYS A N 1 ATOM 1876 C CA . LYS A 1 251 ? 9.509 -21.869 -5.007 1.00 25.05 ? 251 LYS A CA 1 ATOM 1877 C C . LYS A 1 251 ? 8.232 -21.310 -5.619 1.00 32.32 ? 251 LYS A C 1 ATOM 1878 O O . LYS A 1 251 ? 7.702 -20.291 -5.183 1.00 27.48 ? 251 LYS A O 1 ATOM 1879 C CB . LYS A 1 251 ? 10.050 -20.961 -3.913 1.00 28.06 ? 251 LYS A CB 1 ATOM 1880 C CG . LYS A 1 251 ? 11.290 -21.533 -3.235 1.00 28.89 ? 251 LYS A CG 1 ATOM 1881 C CD . LYS A 1 251 ? 11.616 -20.808 -1.937 1.00 30.15 ? 251 LYS A CD 1 ATOM 1882 C CE . LYS A 1 251 ? 12.827 -21.441 -1.264 1.00 40.71 ? 251 LYS A CE 1 ATOM 1883 N NZ . LYS A 1 251 ? 12.976 -20.977 0.146 1.00 37.32 ? 251 LYS A NZ 1 ATOM 1884 N N . VAL A 1 252 ? 7.732 -22.005 -6.638 1.00 30.20 ? 252 VAL A N 1 ATOM 1885 C CA . VAL A 1 252 ? 6.477 -21.682 -7.309 1.00 27.18 ? 252 VAL A CA 1 ATOM 1886 C C . VAL A 1 252 ? 5.512 -22.833 -7.062 1.00 36.07 ? 252 VAL A C 1 ATOM 1887 O O . VAL A 1 252 ? 5.865 -24.003 -7.257 1.00 33.08 ? 252 VAL A O 1 ATOM 1888 C CB . VAL A 1 252 ? 6.684 -21.452 -8.819 1.00 36.59 ? 252 VAL A CB 1 ATOM 1889 C CG1 . VAL A 1 252 ? 5.349 -21.247 -9.524 1.00 33.01 ? 252 VAL A CG1 1 ATOM 1890 C CG2 . VAL A 1 252 ? 7.604 -20.253 -9.062 1.00 35.17 ? 252 VAL A CG2 1 ATOM 1891 N N . ILE A 1 253 ? 4.310 -22.510 -6.603 1.00 27.99 ? 253 ILE A N 1 ATOM 1892 C CA . ILE A 1 253 ? 3.233 -23.479 -6.454 1.00 28.28 ? 253 ILE A CA 1 ATOM 1893 C C . ILE A 1 253 ? 2.320 -23.336 -7.663 1.00 32.25 ? 253 ILE A C 1 ATOM 1894 O O . ILE A 1 253 ? 1.757 -22.259 -7.892 1.00 31.22 ? 253 ILE A O 1 ATOM 1895 C CB . ILE A 1 253 ? 2.458 -23.247 -5.148 1.00 27.20 ? 253 ILE A CB 1 ATOM 1896 C CG1 . ILE A 1 253 ? 3.338 -23.569 -3.943 1.00 30.12 ? 253 ILE A CG1 1 ATOM 1897 C CG2 . ILE A 1 253 ? 1.153 -24.055 -5.134 1.00 27.14 ? 253 ILE A CG2 1 ATOM 1898 C CD1 . ILE A 1 253 ? 2.752 -23.076 -2.624 1.00 30.60 ? 253 ILE A CD1 1 ATOM 1899 N N . GLU A 1 254 ? 2.181 -24.407 -8.451 1.00 31.74 ? 254 GLU A N 1 ATOM 1900 C CA . GLU A 1 254 ? 1.354 -24.388 -9.664 1.00 35.89 ? 254 GLU A CA 1 ATOM 1901 C C . GLU A 1 254 ? -0.016 -24.979 -9.343 1.00 31.90 ? 254 GLU A C 1 ATOM 1902 O O . GLU A 1 254 ? -0.170 -26.198 -9.266 1.00 33.14 ? 254 GLU A O 1 ATOM 1903 C CB . GLU A 1 254 ? 2.026 -25.171 -10.792 1.00 38.16 ? 254 GLU A CB 1 ATOM 1904 C CG . GLU A 1 254 ? 3.434 -24.722 -11.175 1.00 33.96 ? 254 GLU A CG 1 ATOM 1905 C CD . GLU A 1 254 ? 3.950 -25.420 -12.434 1.00 44.23 ? 254 GLU A CD 1 ATOM 1906 O OE1 . GLU A 1 254 ? 4.599 -26.484 -12.317 1.00 46.97 ? 254 GLU A OE1 1 ATOM 1907 O OE2 . GLU A 1 254 ? 3.693 -24.914 -13.548 1.00 44.06 ? 254 GLU A OE2 1 ATOM 1908 N N . LEU A 1 255 ? -1.029 -24.123 -9.180 1.00 31.37 ? 255 LEU A N 1 ATOM 1909 C CA . LEU A 1 255 ? -2.344 -24.618 -8.768 1.00 29.74 ? 255 LEU A CA 1 ATOM 1910 C C . LEU A 1 255 ? -2.916 -25.617 -9.767 1.00 27.26 ? 255 LEU A C 1 ATOM 1911 O O . LEU A 1 255 ? -3.630 -26.545 -9.379 1.00 30.13 ? 255 LEU A O 1 ATOM 1912 C CB . LEU A 1 255 ? -3.334 -23.463 -8.592 1.00 35.76 ? 255 LEU A CB 1 ATOM 1913 C CG . LEU A 1 255 ? -3.200 -22.551 -7.369 1.00 36.39 ? 255 LEU A CG 1 ATOM 1914 C CD1 . LEU A 1 255 ? -4.325 -21.513 -7.376 1.00 27.60 ? 255 LEU A CD1 1 ATOM 1915 C CD2 . LEU A 1 255 ? -3.196 -23.351 -6.065 1.00 33.87 ? 255 LEU A CD2 1 ATOM 1916 N N . SER A 1 256 ? -2.640 -25.430 -11.061 1.00 26.85 ? 256 SER A N 1 ATOM 1917 C CA . SER A 1 256 ? -3.232 -26.318 -12.056 1.00 31.24 ? 256 SER A CA 1 ATOM 1918 C C . SER A 1 256 ? -2.664 -27.730 -11.988 1.00 35.67 ? 256 SER A C 1 ATOM 1919 O O . SER A 1 256 ? -3.172 -28.618 -12.684 1.00 31.60 ? 256 SER A O 1 ATOM 1920 C CB . SER A 1 256 ? -3.052 -25.748 -13.464 1.00 30.82 ? 256 SER A CB 1 ATOM 1921 O OG . SER A 1 256 ? -1.714 -25.862 -13.909 1.00 34.50 ? 256 SER A OG 1 ATOM 1922 N N . ASN A 1 257 ? -1.635 -27.961 -11.175 1.00 30.45 ? 257 ASN A N 1 ATOM 1923 C CA . ASN A 1 257 ? -1.195 -29.324 -10.895 1.00 28.18 ? 257 ASN A CA 1 ATOM 1924 C C . ASN A 1 257 ? -2.083 -30.021 -9.878 1.00 31.69 ? 257 ASN A C 1 ATOM 1925 O O . ASN A 1 257 ? -1.916 -31.223 -9.649 1.00 30.48 ? 257 ASN A O 1 ATOM 1926 C CB . ASN A 1 257 ? 0.251 -29.335 -10.381 1.00 33.40 ? 257 ASN A CB 1 ATOM 1927 C CG . ASN A 1 257 ? 1.276 -29.059 -11.475 1.00 34.87 ? 257 ASN A CG 1 ATOM 1928 O OD1 . ASN A 1 257 ? 0.930 -28.745 -12.610 1.00 40.24 ? 257 ASN A OD1 1 ATOM 1929 N ND2 . ASN A 1 257 ? 2.548 -29.166 -11.124 1.00 39.25 ? 257 ASN A ND2 1 ATOM 1930 N N . TYR A 1 258 ? -3.017 -29.307 -9.255 1.00 25.84 ? 258 TYR A N 1 ATOM 1931 C CA . TYR A 1 258 ? -3.813 -29.898 -8.193 1.00 25.46 ? 258 TYR A CA 1 ATOM 1932 C C . TYR A 1 258 ? -5.305 -29.838 -8.439 1.00 33.89 ? 258 TYR A C 1 ATOM 1933 O O . TYR A 1 258 ? -6.018 -30.753 -8.027 1.00 39.41 ? 258 TYR A O 1 ATOM 1934 C CB . TYR A 1 258 ? -3.522 -29.211 -6.854 1.00 30.98 ? 258 TYR A CB 1 ATOM 1935 C CG . TYR A 1 258 ? -2.074 -29.264 -6.452 1.00 30.86 ? 258 TYR A CG 1 ATOM 1936 C CD1 . TYR A 1 258 ? -1.554 -30.378 -5.822 1.00 28.50 ? 258 TYR A CD1 1 ATOM 1937 C CD2 . TYR A 1 258 ? -1.227 -28.192 -6.698 1.00 32.65 ? 258 TYR A CD2 1 ATOM 1938 C CE1 . TYR A 1 258 ? -0.222 -30.428 -5.442 1.00 37.03 ? 258 TYR A CE1 1 ATOM 1939 C CE2 . TYR A 1 258 ? 0.105 -28.230 -6.320 1.00 30.57 ? 258 TYR A CE2 1 ATOM 1940 C CZ . TYR A 1 258 ? 0.603 -29.354 -5.697 1.00 38.83 ? 258 TYR A CZ 1 ATOM 1941 O OH . TYR A 1 258 ? 1.925 -29.402 -5.317 1.00 37.73 ? 258 TYR A OH 1 ATOM 1942 N N . ILE A 1 259 ? -5.801 -28.786 -9.083 1.00 30.39 ? 259 ILE A N 1 ATOM 1943 C CA . ILE A 1 259 ? -7.229 -28.631 -9.297 1.00 36.87 ? 259 ILE A CA 1 ATOM 1944 C C . ILE A 1 259 ? -7.459 -28.158 -10.723 1.00 37.42 ? 259 ILE A C 1 ATOM 1945 O O . ILE A 1 259 ? -6.596 -27.535 -11.348 1.00 39.03 ? 259 ILE A O 1 ATOM 1946 C CB . ILE A 1 259 ? -7.857 -27.647 -8.286 1.00 35.33 ? 259 ILE A CB 1 ATOM 1947 C CG1 . ILE A 1 259 ? -7.264 -26.256 -8.489 1.00 36.39 ? 259 ILE A CG1 1 ATOM 1948 C CG2 . ILE A 1 259 ? -7.646 -28.129 -6.843 1.00 31.24 ? 259 ILE A CG2 1 ATOM 1949 C CD1 . ILE A 1 259 ? -7.899 -25.177 -7.622 1.00 39.62 ? 259 ILE A CD1 1 ATOM 1950 N N A SER A 1 260 ? -8.644 -28.462 -11.238 0.50 38.30 ? 260 SER A N 1 ATOM 1951 N N B SER A 1 260 ? -8.645 -28.459 -11.238 0.50 38.30 ? 260 SER A N 1 ATOM 1952 C CA A SER A 1 260 ? -9.032 -28.008 -12.561 0.50 35.65 ? 260 SER A CA 1 ATOM 1953 C CA B SER A 1 260 ? -9.032 -28.012 -12.565 0.50 35.65 ? 260 SER A CA 1 ATOM 1954 C C A SER A 1 260 ? -9.681 -26.638 -12.463 0.50 36.32 ? 260 SER A C 1 ATOM 1955 C C B SER A 1 260 ? -9.689 -26.645 -12.471 0.50 36.33 ? 260 SER A C 1 ATOM 1956 O O A SER A 1 260 ? -10.470 -26.376 -11.551 0.50 35.99 ? 260 SER A O 1 ATOM 1957 O O B SER A 1 260 ? -10.495 -26.392 -11.571 0.50 35.99 ? 260 SER A O 1 ATOM 1958 C CB A SER A 1 260 ? -9.997 -28.995 -13.215 0.50 38.09 ? 260 SER A CB 1 ATOM 1959 C CB B SER A 1 260 ? -9.992 -29.006 -13.215 0.50 38.09 ? 260 SER A CB 1 ATOM 1960 O OG A SER A 1 260 ? -10.519 -28.458 -14.416 0.50 32.09 ? 260 SER A OG 1 ATOM 1961 O OG B SER A 1 260 ? -11.244 -29.002 -12.551 0.50 37.31 ? 260 SER A OG 1 ATOM 1962 N N . LEU A 1 261 ? -9.342 -25.765 -13.411 1.00 37.10 ? 261 LEU A N 1 ATOM 1963 C CA . LEU A 1 261 ? -9.961 -24.445 -13.450 1.00 43.27 ? 261 LEU A CA 1 ATOM 1964 C C . LEU A 1 261 ? -11.461 -24.553 -13.682 1.00 42.53 ? 261 LEU A C 1 ATOM 1965 O O . LEU A 1 261 ? -12.223 -23.668 -13.278 1.00 38.89 ? 261 LEU A O 1 ATOM 1966 C CB . LEU A 1 261 ? -9.305 -23.594 -14.537 1.00 47.22 ? 261 LEU A CB 1 ATOM 1967 C CG . LEU A 1 261 ? -8.033 -22.807 -14.200 1.00 49.77 ? 261 LEU A CG 1 ATOM 1968 C CD1 . LEU A 1 261 ? -7.183 -23.476 -13.121 1.00 48.83 ? 261 LEU A CD1 1 ATOM 1969 C CD2 . LEU A 1 261 ? -7.215 -22.605 -15.469 1.00 53.08 ? 261 LEU A CD2 1 ATOM 1970 N N . ASP A 1 262 ? -11.903 -25.648 -14.305 1.00 39.38 ? 262 ASP A N 1 ATOM 1971 C CA . ASP A 1 262 ? -13.323 -25.879 -14.508 1.00 39.31 ? 262 ASP A CA 1 ATOM 1972 C C . ASP A 1 262 ? -14.075 -26.048 -13.197 1.00 35.45 ? 262 ASP A C 1 ATOM 1973 O O . ASP A 1 262 ? -15.304 -25.933 -13.185 1.00 40.81 ? 262 ASP A O 1 ATOM 1974 C CB . ASP A 1 262 ? -13.529 -27.114 -15.387 1.00 44.51 ? 262 ASP A CB 1 ATOM 1975 C CG . ASP A 1 262 ? -12.921 -26.960 -16.769 1.00 50.94 ? 262 ASP A CG 1 ATOM 1976 O OD1 . ASP A 1 262 ? -12.826 -25.813 -17.262 1.00 51.52 ? 262 ASP A OD1 1 ATOM 1977 O OD2 . ASP A 1 262 ? -12.542 -27.993 -17.366 1.00 56.18 ? 262 ASP A OD2 1 ATOM 1978 N N . ASP A 1 263 ? -13.382 -26.335 -12.100 1.00 29.43 ? 263 ASP A N 1 ATOM 1979 C CA . ASP A 1 263 ? -14.037 -26.456 -10.808 1.00 31.23 ? 263 ASP A CA 1 ATOM 1980 C C . ASP A 1 263 ? -14.075 -25.134 -10.057 1.00 29.67 ? 263 ASP A C 1 ATOM 1981 O O . ASP A 1 263 ? -14.456 -25.111 -8.883 1.00 28.10 ? 263 ASP A O 1 ATOM 1982 C CB . ASP A 1 263 ? -13.344 -27.520 -9.950 1.00 32.84 ? 263 ASP A CB 1 ATOM 1983 C CG . ASP A 1 263 ? -13.574 -28.934 -10.466 1.00 40.66 ? 263 ASP A CG 1 ATOM 1984 O OD1 . ASP A 1 263 ? -14.572 -29.157 -11.186 1.00 38.48 ? 263 ASP A OD1 1 ATOM 1985 O OD2 . ASP A 1 263 ? -12.756 -29.823 -10.144 1.00 40.58 ? 263 ASP A OD2 1 ATOM 1986 N N . LEU A 1 264 ? -13.685 -24.043 -10.709 1.00 28.72 ? 264 LEU A N 1 ATOM 1987 C CA . LEU A 1 264 ? -13.611 -22.730 -10.089 1.00 32.27 ? 264 LEU A CA 1 ATOM 1988 C C . LEU A 1 264 ? -14.490 -21.762 -10.857 1.00 28.37 ? 264 LEU A C 1 ATOM 1989 O O . LEU A 1 264 ? -14.378 -21.650 -12.081 1.00 32.03 ? 264 LEU A O 1 ATOM 1990 C CB . LEU A 1 264 ? -12.176 -22.208 -10.059 1.00 34.17 ? 264 LEU A CB 1 ATOM 1991 C CG . LEU A 1 264 ? -11.209 -22.988 -9.173 1.00 30.04 ? 264 LEU A CG 1 ATOM 1992 C CD1 . LEU A 1 264 ? -9.777 -22.656 -9.558 1.00 39.98 ? 264 LEU A CD1 1 ATOM 1993 C CD2 . LEU A 1 264 ? -11.467 -22.686 -7.710 1.00 31.12 ? 264 LEU A CD2 1 ATOM 1994 N N . GLN A 1 265 ? -15.360 -21.070 -10.123 1.00 25.54 ? 265 GLN A N 1 ATOM 1995 C CA . GLN A 1 265 ? -16.125 -19.965 -10.686 1.00 26.90 ? 265 GLN A CA 1 ATOM 1996 C C . GLN A 1 265 ? -15.226 -18.769 -10.982 1.00 31.33 ? 265 GLN A C 1 ATOM 1997 O O . GLN A 1 265 ? -15.422 -18.057 -11.978 1.00 28.05 ? 265 GLN A O 1 ATOM 1998 C CB . GLN A 1 265 ? -17.210 -19.578 -9.686 1.00 33.55 ? 265 GLN A CB 1 ATOM 1999 C CG . GLN A 1 265 ? -18.593 -19.416 -10.224 1.00 48.94 ? 265 GLN A CG 1 ATOM 2000 C CD . GLN A 1 265 ? -19.564 -19.127 -9.100 1.00 52.44 ? 265 GLN A CD 1 ATOM 2001 O OE1 . GLN A 1 265 ? -19.377 -19.596 -7.975 1.00 52.77 ? 265 GLN A OE1 1 ATOM 2002 N NE2 . GLN A 1 265 ? -20.588 -18.339 -9.387 1.00 60.17 ? 265 GLN A NE2 1 ATOM 2003 N N . GLN A 1 266 ? -14.245 -18.522 -10.118 1.00 26.42 ? 266 GLN A N 1 ATOM 2004 C CA . GLN A 1 266 ? -13.402 -17.339 -10.222 1.00 22.04 ? 266 GLN A CA 1 ATOM 2005 C C . GLN A 1 266 ? -12.119 -17.583 -9.435 1.00 24.22 ? 266 GLN A C 1 ATOM 2006 O O . GLN A 1 266 ? -12.113 -18.333 -8.456 1.00 21.18 ? 266 GLN A O 1 ATOM 2007 C CB . GLN A 1 266 ? -14.133 -16.100 -9.689 1.00 24.89 ? 266 GLN A CB 1 ATOM 2008 C CG . GLN A 1 266 ? -13.362 -14.792 -9.828 1.00 23.89 ? 266 GLN A CG 1 ATOM 2009 C CD . GLN A 1 266 ? -13.110 -14.410 -11.272 1.00 29.65 ? 266 GLN A CD 1 ATOM 2010 O OE1 . GLN A 1 266 ? -12.229 -14.961 -11.940 1.00 34.33 ? 266 GLN A OE1 1 ATOM 2011 N NE2 . GLN A 1 266 ? -13.879 -13.453 -11.763 1.00 28.09 ? 266 GLN A NE2 1 ATOM 2012 N N . VAL A 1 267 ? -11.034 -16.959 -9.895 1.00 26.82 ? 267 VAL A N 1 ATOM 2013 C CA . VAL A 1 267 ? -9.762 -16.876 -9.174 1.00 27.24 ? 267 VAL A CA 1 ATOM 2014 C C . VAL A 1 267 ? -9.247 -15.457 -9.331 1.00 23.15 ? 267 VAL A C 1 ATOM 2015 O O . VAL A 1 267 ? -9.331 -14.893 -10.422 1.00 24.65 ? 267 VAL A O 1 ATOM 2016 C CB . VAL A 1 267 ? -8.716 -17.864 -9.729 1.00 25.87 ? 267 VAL A CB 1 ATOM 2017 C CG1 . VAL A 1 267 ? -7.386 -17.752 -8.961 1.00 29.52 ? 267 VAL A CG1 1 ATOM 2018 C CG2 . VAL A 1 267 ? -9.236 -19.247 -9.678 1.00 32.37 ? 267 VAL A CG2 1 ATOM 2019 N N . LYS A 1 268 ? -8.715 -14.876 -8.250 1.00 22.65 ? 268 LYS A N 1 ATOM 2020 C CA . LYS A 1 268 ? -8.172 -13.519 -8.278 1.00 22.15 ? 268 LYS A CA 1 ATOM 2021 C C . LYS A 1 268 ? -6.768 -13.503 -7.683 1.00 21.75 ? 268 LYS A C 1 ATOM 2022 O O . LYS A 1 268 ? -6.547 -14.040 -6.593 1.00 21.64 ? 268 LYS A O 1 ATOM 2023 C CB . LYS A 1 268 ? -9.072 -12.531 -7.520 1.00 20.67 ? 268 LYS A CB 1 ATOM 2024 C CG . LYS A 1 268 ? -10.370 -12.177 -8.250 1.00 20.08 ? 268 LYS A CG 1 ATOM 2025 C CD . LYS A 1 268 ? -10.070 -11.576 -9.636 1.00 23.94 ? 268 LYS A CD 1 ATOM 2026 C CE . LYS A 1 268 ? -11.329 -11.105 -10.362 1.00 25.87 ? 268 LYS A CE 1 ATOM 2027 N NZ . LYS A 1 268 ? -11.036 -10.655 -11.771 1.00 22.31 ? 268 LYS A NZ 1 ATOM 2028 N N . ASP A 1 269 ? -5.833 -12.919 -8.438 1.00 21.99 ? 269 ASP A N 1 ATOM 2029 C CA . ASP A 1 269 ? -4.433 -12.646 -8.112 1.00 19.89 ? 269 ASP A CA 1 ATOM 2030 C C . ASP A 1 269 ? -3.524 -13.869 -8.226 1.00 29.86 ? 269 ASP A C 1 ATOM 2031 O O . ASP A 1 269 ? -3.971 -14.999 -8.459 1.00 24.06 ? 269 ASP A O 1 ATOM 2032 C CB . ASP A 1 269 ? -4.291 -12.008 -6.717 1.00 21.29 ? 269 ASP A CB 1 ATOM 2033 C CG . ASP A 1 269 ? -3.184 -10.943 -6.662 1.00 24.52 ? 269 ASP A CG 1 ATOM 2034 O OD1 . ASP A 1 269 ? -2.278 -10.980 -7.518 1.00 26.20 ? 269 ASP A OD1 1 ATOM 2035 O OD2 . ASP A 1 269 ? -3.209 -10.056 -5.769 1.00 26.55 ? 269 ASP A OD2 1 ATOM 2036 N N . ARG A 1 270 ? -2.228 -13.603 -8.120 1.00 24.28 ? 270 ARG A N 1 ATOM 2037 C CA . ARG A 1 270 ? -1.150 -14.577 -8.163 1.00 25.68 ? 270 ARG A CA 1 ATOM 2038 C C . ARG A 1 270 ? -0.104 -14.092 -7.178 1.00 29.19 ? 270 ARG A C 1 ATOM 2039 O O . ARG A 1 270 ? 0.059 -12.886 -6.989 1.00 31.03 ? 270 ARG A O 1 ATOM 2040 C CB . ARG A 1 270 ? -0.528 -14.685 -9.566 1.00 28.62 ? 270 ARG A CB 1 ATOM 2041 C CG . ARG A 1 270 ? -1.526 -15.017 -10.667 1.00 41.79 ? 270 ARG A CG 1 ATOM 2042 C CD . ARG A 1 270 ? -0.884 -15.050 -12.053 1.00 55.65 ? 270 ARG A CD 1 ATOM 2043 N NE . ARG A 1 270 ? -0.480 -13.729 -12.536 1.00 54.46 ? 270 ARG A NE 1 ATOM 2044 C CZ . ARG A 1 270 ? -0.180 -13.462 -13.805 1.00 53.70 ? 270 ARG A CZ 1 ATOM 2045 N NH1 . ARG A 1 270 ? 0.180 -12.237 -14.168 1.00 53.00 ? 270 ARG A NH1 1 ATOM 2046 N NH2 . ARG A 1 270 ? -0.255 -14.421 -14.718 1.00 57.75 ? 270 ARG A NH2 1 ATOM 2047 N N . GLY A 1 271 ? 0.619 -15.017 -6.567 1.00 24.37 ? 271 GLY A N 1 ATOM 2048 C CA . GLY A 1 271 ? 1.647 -14.617 -5.640 1.00 23.53 ? 271 GLY A CA 1 ATOM 2049 C C . GLY A 1 271 ? 1.395 -15.142 -4.246 1.00 23.69 ? 271 GLY A C 1 ATOM 2050 O O . GLY A 1 271 ? 1.217 -16.346 -4.038 1.00 28.97 ? 271 GLY A O 1 ATOM 2051 N N . PRO A 1 272 ? 1.410 -14.256 -3.248 1.00 21.16 ? 272 PRO A N 1 ATOM 2052 C CA . PRO A 1 272 ? 1.275 -14.733 -1.867 1.00 19.82 ? 272 PRO A CA 1 ATOM 2053 C C . PRO A 1 272 ? -0.154 -14.965 -1.397 1.00 21.67 ? 272 PRO A C 1 ATOM 2054 O O . PRO A 1 272 ? -0.380 -15.821 -0.537 1.00 23.47 ? 272 PRO A O 1 ATOM 2055 C CB . PRO A 1 272 ? 1.952 -13.619 -1.052 1.00 25.50 ? 272 PRO A CB 1 ATOM 2056 C CG . PRO A 1 272 ? 1.821 -12.425 -1.862 1.00 31.27 ? 272 PRO A CG 1 ATOM 2057 C CD . PRO A 1 272 ? 1.866 -12.856 -3.306 1.00 24.17 ? 272 PRO A CD 1 ATOM 2058 N N . VAL A 1 273 ? -1.124 -14.204 -1.907 1.00 19.61 ? 273 VAL A N 1 ATOM 2059 C CA . VAL A 1 273 ? -2.507 -14.293 -1.441 1.00 22.27 ? 273 VAL A CA 1 ATOM 2060 C C . VAL A 1 273 ? -3.405 -14.431 -2.657 1.00 24.63 ? 273 VAL A C 1 ATOM 2061 O O . VAL A 1 273 ? -3.446 -13.531 -3.507 1.00 26.04 ? 273 VAL A O 1 ATOM 2062 C CB . VAL A 1 273 ? -2.935 -13.077 -0.604 1.00 23.47 ? 273 VAL A CB 1 ATOM 2063 C CG1 . VAL A 1 273 ? -4.349 -13.286 -0.057 1.00 21.23 ? 273 VAL A CG1 1 ATOM 2064 C CG2 . VAL A 1 273 ? -1.945 -12.822 0.531 1.00 25.00 ? 273 VAL A CG2 1 ATOM 2065 N N . VAL A 1 274 ? -4.132 -15.542 -2.732 1.00 21.94 ? 274 VAL A N 1 ATOM 2066 C CA . VAL A 1 274 ? -4.964 -15.866 -3.882 1.00 21.23 ? 274 VAL A CA 1 ATOM 2067 C C . VAL A 1 274 ? -6.369 -16.178 -3.391 1.00 18.44 ? 274 VAL A C 1 ATOM 2068 O O . VAL A 1 274 ? -6.548 -16.945 -2.443 1.00 21.30 ? 274 VAL A O 1 ATOM 2069 C CB . VAL A 1 274 ? -4.385 -17.044 -4.690 1.00 22.37 ? 274 VAL A CB 1 ATOM 2070 C CG1 . VAL A 1 274 ? -5.349 -17.464 -5.803 1.00 24.26 ? 274 VAL A CG1 1 ATOM 2071 C CG2 . VAL A 1 274 ? -3.028 -16.656 -5.269 1.00 23.90 ? 274 VAL A CG2 1 ATOM 2072 N N . SER A 1 275 ? -7.364 -15.570 -4.030 1.00 18.44 ? 275 SER A N 1 ATOM 2073 C CA . SER A 1 275 ? -8.763 -15.747 -3.689 1.00 17.60 ? 275 SER A CA 1 ATOM 2074 C C . SER A 1 275 ? -9.376 -16.740 -4.679 1.00 20.65 ? 275 SER A C 1 ATOM 2075 O O . SER A 1 275 ? -9.200 -16.589 -5.893 1.00 22.50 ? 275 SER A O 1 ATOM 2076 C CB . SER A 1 275 ? -9.507 -14.407 -3.758 1.00 19.38 ? 275 SER A CB 1 ATOM 2077 O OG . SER A 1 275 ? -9.018 -13.475 -2.793 1.00 21.01 ? 275 SER A OG 1 ATOM 2078 N N . LEU A 1 276 ? -10.084 -17.745 -4.154 1.00 19.05 ? 276 LEU A N 1 ATOM 2079 C CA . LEU A 1 276 ? -10.723 -18.808 -4.939 1.00 19.25 ? 276 LEU A CA 1 ATOM 2080 C C . LEU A 1 276 ? -12.215 -18.884 -4.642 1.00 21.17 ? 276 LEU A C 1 ATOM 2081 O O . LEU A 1 276 ? -12.620 -18.887 -3.478 1.00 21.78 ? 276 LEU A O 1 ATOM 2082 C CB . LEU A 1 276 ? -10.121 -20.180 -4.622 1.00 22.88 ? 276 LEU A CB 1 ATOM 2083 C CG . LEU A 1 276 ? -8.653 -20.447 -4.886 1.00 29.12 ? 276 LEU A CG 1 ATOM 2084 C CD1 . LEU A 1 276 ? -8.363 -21.910 -4.577 1.00 32.02 ? 276 LEU A CD1 1 ATOM 2085 C CD2 . LEU A 1 276 ? -8.320 -20.127 -6.298 1.00 24.51 ? 276 LEU A CD2 1 ATOM 2086 N N . TRP A 1 277 ? -13.021 -19.016 -5.693 1.00 19.68 ? 277 TRP A N 1 ATOM 2087 C CA . TRP A 1 277 ? -14.463 -19.227 -5.573 1.00 21.41 ? 277 TRP A CA 1 ATOM 2088 C C . TRP A 1 277 ? -14.816 -20.558 -6.234 1.00 22.73 ? 277 TRP A C 1 ATOM 2089 O O . TRP A 1 277 ? -14.927 -20.616 -7.467 1.00 23.89 ? 277 TRP A O 1 ATOM 2090 C CB . TRP A 1 277 ? -15.229 -18.081 -6.249 1.00 20.21 ? 277 TRP A CB 1 ATOM 2091 C CG . TRP A 1 277 ? -15.179 -16.711 -5.568 1.00 21.15 ? 277 TRP A CG 1 ATOM 2092 C CD1 . TRP A 1 277 ? -16.157 -16.149 -4.816 1.00 22.35 ? 277 TRP A CD1 1 ATOM 2093 C CD2 . TRP A 1 277 ? -14.127 -15.732 -5.660 1.00 23.75 ? 277 TRP A CD2 1 ATOM 2094 N NE1 . TRP A 1 277 ? -15.778 -14.886 -4.402 1.00 21.77 ? 277 TRP A NE1 1 ATOM 2095 C CE2 . TRP A 1 277 ? -14.533 -14.608 -4.904 1.00 22.77 ? 277 TRP A CE2 1 ATOM 2096 C CE3 . TRP A 1 277 ? -12.878 -15.703 -6.293 1.00 21.08 ? 277 TRP A CE3 1 ATOM 2097 C CZ2 . TRP A 1 277 ? -13.729 -13.465 -4.755 1.00 21.57 ? 277 TRP A CZ2 1 ATOM 2098 C CZ3 . TRP A 1 277 ? -12.076 -14.566 -6.149 1.00 22.69 ? 277 TRP A CZ3 1 ATOM 2099 C CH2 . TRP A 1 277 ? -12.514 -13.458 -5.397 1.00 24.07 ? 277 TRP A CH2 1 ATOM 2100 N N . PRO A 1 278 ? -14.956 -21.661 -5.486 1.00 23.78 ? 278 PRO A N 1 ATOM 2101 C CA . PRO A 1 278 ? -15.322 -22.938 -6.122 1.00 26.97 ? 278 PRO A CA 1 ATOM 2102 C C . PRO A 1 278 ? -16.710 -22.894 -6.747 1.00 31.81 ? 278 PRO A C 1 ATOM 2103 O O . PRO A 1 278 ? -17.590 -22.147 -6.309 1.00 30.57 ? 278 PRO A O 1 ATOM 2104 C CB . PRO A 1 278 ? -15.284 -23.945 -4.967 1.00 26.42 ? 278 PRO A CB 1 ATOM 2105 C CG . PRO A 1 278 ? -14.415 -23.318 -3.919 1.00 28.98 ? 278 PRO A CG 1 ATOM 2106 C CD . PRO A 1 278 ? -14.613 -21.824 -4.067 1.00 23.19 ? 278 PRO A CD 1 ATOM 2107 N N . VAL A 1 279 ? -16.906 -23.724 -7.771 1.00 26.62 ? 279 VAL A N 1 ATOM 2108 C CA . VAL A 1 279 ? -18.254 -23.956 -8.295 1.00 29.47 ? 279 VAL A CA 1 ATOM 2109 C C . VAL A 1 279 ? -19.073 -24.644 -7.205 1.00 29.57 ? 279 VAL A C 1 ATOM 2110 O O . VAL A 1 279 ? -18.501 -25.269 -6.300 1.00 30.83 ? 279 VAL A O 1 ATOM 2111 C CB . VAL A 1 279 ? -18.231 -24.784 -9.592 1.00 31.10 ? 279 VAL A CB 1 ATOM 2112 C CG1 . VAL A 1 279 ? -17.401 -24.102 -10.668 1.00 29.39 ? 279 VAL A CG1 1 ATOM 2113 C CG2 . VAL A 1 279 ? -17.710 -26.172 -9.327 1.00 33.85 ? 279 VAL A CG2 1 ATOM 2114 N N . PRO A 1 280 ? -20.401 -24.536 -7.216 1.00 34.18 ? 280 PRO A N 1 ATOM 2115 C CA . PRO A 1 280 ? -21.192 -25.242 -6.200 1.00 36.99 ? 280 PRO A CA 1 ATOM 2116 C C . PRO A 1 280 ? -20.952 -26.748 -6.265 1.00 34.31 ? 280 PRO A C 1 ATOM 2117 O O . PRO A 1 280 ? -20.903 -27.342 -7.342 1.00 35.78 ? 280 PRO A O 1 ATOM 2118 C CB . PRO A 1 280 ? -22.637 -24.879 -6.559 1.00 40.28 ? 280 PRO A CB 1 ATOM 2119 C CG . PRO A 1 280 ? -22.517 -23.584 -7.338 1.00 35.73 ? 280 PRO A CG 1 ATOM 2120 C CD . PRO A 1 280 ? -21.242 -23.717 -8.107 1.00 31.69 ? 280 PRO A CD 1 ATOM 2121 N N . GLY A 1 281 ? -20.771 -27.356 -5.094 1.00 34.76 ? 281 GLY A N 1 ATOM 2122 C CA . GLY A 1 281 ? -20.506 -28.775 -4.992 1.00 35.33 ? 281 GLY A CA 1 ATOM 2123 C C . GLY A 1 281 ? -19.041 -29.166 -5.006 1.00 43.35 ? 281 GLY A C 1 ATOM 2124 O O . GLY A 1 281 ? -18.729 -30.343 -4.789 1.00 35.76 ? 281 GLY A O 1 ATOM 2125 N N . LYS A 1 282 ? -18.130 -28.224 -5.254 1.00 36.67 ? 282 LYS A N 1 ATOM 2126 C CA . LYS A 1 282 ? -16.705 -28.529 -5.294 1.00 33.20 ? 282 LYS A CA 1 ATOM 2127 C C . LYS A 1 282 ? -15.925 -27.846 -4.178 1.00 28.56 ? 282 LYS A C 1 ATOM 2128 O O . LYS A 1 282 ? -14.698 -27.971 -4.129 1.00 26.86 ? 282 LYS A O 1 ATOM 2129 C CB . LYS A 1 282 ? -16.120 -28.144 -6.651 1.00 31.67 ? 282 LYS A CB 1 ATOM 2130 C CG . LYS A 1 282 ? -16.568 -29.038 -7.803 1.00 40.89 ? 282 LYS A CG 1 ATOM 2131 C CD . LYS A 1 282 ? -16.160 -30.485 -7.565 1.00 39.44 ? 282 LYS A CD 1 ATOM 2132 C CE . LYS A 1 282 ? -16.827 -31.405 -8.569 1.00 42.09 ? 282 LYS A CE 1 ATOM 2133 N NZ . LYS A 1 282 ? -17.213 -32.707 -7.952 1.00 49.59 ? 282 LYS A NZ 1 ATOM 2134 N N . HIS A 1 283 ? -16.610 -27.132 -3.283 1.00 27.90 ? 283 HIS A N 1 ATOM 2135 C CA . HIS A 1 283 ? -15.924 -26.400 -2.222 1.00 28.03 ? 283 HIS A CA 1 ATOM 2136 C C . HIS A 1 283 ? -15.078 -27.334 -1.362 1.00 31.71 ? 283 HIS A C 1 ATOM 2137 O O . HIS A 1 283 ? -13.877 -27.102 -1.161 1.00 27.73 ? 283 HIS A O 1 ATOM 2138 C CB . HIS A 1 283 ? -16.952 -25.665 -1.364 1.00 31.74 ? 283 HIS A CB 1 ATOM 2139 C CG . HIS A 1 283 ? -16.350 -24.873 -0.250 1.00 34.74 ? 283 HIS A CG 1 ATOM 2140 N ND1 . HIS A 1 283 ? -15.936 -25.446 0.933 1.00 41.23 ? 283 HIS A ND1 1 ATOM 2141 C CD2 . HIS A 1 283 ? -16.082 -23.549 -0.140 1.00 32.55 ? 283 HIS A CD2 1 ATOM 2142 C CE1 . HIS A 1 283 ? -15.450 -24.507 1.727 1.00 33.57 ? 283 HIS A CE1 1 ATOM 2143 N NE2 . HIS A 1 283 ? -15.528 -23.349 1.100 1.00 31.04 ? 283 HIS A NE2 1 ATOM 2144 N N . SER A 1 284 ? -15.689 -28.401 -0.849 1.00 27.53 ? 284 SER A N 1 ATOM 2145 C CA . SER A 1 284 ? -14.968 -29.296 0.047 1.00 29.70 ? 284 SER A CA 1 ATOM 2146 C C . SER A 1 284 ? -13.811 -29.994 -0.659 1.00 25.98 ? 284 SER A C 1 ATOM 2147 O O . SER A 1 284 ? -12.734 -30.151 -0.074 1.00 29.65 ? 284 SER A O 1 ATOM 2148 C CB . SER A 1 284 ? -15.932 -30.319 0.648 1.00 32.11 ? 284 SER A CB 1 ATOM 2149 O OG . SER A 1 284 ? -15.245 -31.146 1.574 1.00 45.58 ? 284 SER A OG 1 ATOM 2150 N N . GLU A 1 285 ? -14.000 -30.404 -1.911 1.00 26.43 ? 285 GLU A N 1 ATOM 2151 C CA . GLU A 1 285 ? -12.951 -31.138 -2.610 1.00 28.26 ? 285 GLU A CA 1 ATOM 2152 C C . GLU A 1 285 ? -11.751 -30.246 -2.894 1.00 30.16 ? 285 GLU A C 1 ATOM 2153 O O . GLU A 1 285 ? -10.601 -30.652 -2.687 1.00 29.77 ? 285 GLU A O 1 ATOM 2154 C CB . GLU A 1 285 ? -13.504 -31.724 -3.904 1.00 35.79 ? 285 GLU A CB 1 ATOM 2155 C CG . GLU A 1 285 ? -14.485 -32.856 -3.684 1.00 39.98 ? 285 GLU A CG 1 ATOM 2156 C CD . GLU A 1 285 ? -15.190 -33.247 -4.963 1.00 45.51 ? 285 GLU A CD 1 ATOM 2157 O OE1 . GLU A 1 285 ? -16.388 -32.921 -5.112 1.00 47.77 ? 285 GLU A OE1 1 ATOM 2158 O OE2 . GLU A 1 285 ? -14.534 -33.861 -5.828 1.00 47.30 ? 285 GLU A OE2 1 ATOM 2159 N N . ILE A 1 286 ? -12.003 -29.022 -3.370 1.00 26.66 ? 286 ILE A N 1 ATOM 2160 C CA . ILE A 1 286 ? -10.914 -28.073 -3.600 1.00 27.85 ? 286 ILE A CA 1 ATOM 2161 C C . ILE A 1 286 ? -10.188 -27.780 -2.298 1.00 24.99 ? 286 ILE A C 1 ATOM 2162 O O . ILE A 1 286 ? -8.953 -27.766 -2.243 1.00 27.49 ? 286 ILE A O 1 ATOM 2163 C CB . ILE A 1 286 ? -11.440 -26.776 -4.240 1.00 26.33 ? 286 ILE A CB 1 ATOM 2164 C CG1 . ILE A 1 286 ? -12.111 -27.050 -5.585 1.00 31.87 ? 286 ILE A CG1 1 ATOM 2165 C CG2 . ILE A 1 286 ? -10.285 -25.756 -4.391 1.00 27.82 ? 286 ILE A CG2 1 ATOM 2166 C CD1 . ILE A 1 286 ? -11.150 -27.136 -6.753 1.00 41.74 ? 286 ILE A CD1 1 ATOM 2167 N N . TYR A 1 287 ? -10.946 -27.546 -1.227 1.00 22.40 ? 287 TYR A N 1 ATOM 2168 C CA . TYR A 1 287 ? -10.335 -27.293 0.071 1.00 23.37 ? 287 TYR A CA 1 ATOM 2169 C C . TYR A 1 287 ? -9.414 -28.437 0.479 1.00 30.85 ? 287 TYR A C 1 ATOM 2170 O O . TYR A 1 287 ? -8.249 -28.223 0.834 1.00 26.64 ? 287 TYR A O 1 ATOM 2171 C CB . TYR A 1 287 ? -11.418 -27.078 1.121 1.00 23.06 ? 287 TYR A CB 1 ATOM 2172 C CG . TYR A 1 287 ? -10.855 -26.933 2.503 1.00 29.17 ? 287 TYR A CG 1 ATOM 2173 C CD1 . TYR A 1 287 ? -10.182 -25.772 2.876 1.00 29.12 ? 287 TYR A CD1 1 ATOM 2174 C CD2 . TYR A 1 287 ? -10.977 -27.950 3.436 1.00 31.11 ? 287 TYR A CD2 1 ATOM 2175 C CE1 . TYR A 1 287 ? -9.658 -25.627 4.138 1.00 30.82 ? 287 TYR A CE1 1 ATOM 2176 C CE2 . TYR A 1 287 ? -10.454 -27.816 4.704 1.00 34.87 ? 287 TYR A CE2 1 ATOM 2177 C CZ . TYR A 1 287 ? -9.798 -26.647 5.051 1.00 35.61 ? 287 TYR A CZ 1 ATOM 2178 O OH . TYR A 1 287 ? -9.268 -26.494 6.307 1.00 39.80 ? 287 TYR A OH 1 ATOM 2179 N N . HIS A 1 288 ? -9.919 -29.674 0.415 1.00 28.11 ? 288 HIS A N 1 ATOM 2180 C CA . HIS A 1 288 ? -9.131 -30.800 0.914 1.00 28.99 ? 288 HIS A CA 1 ATOM 2181 C C . HIS A 1 288 ? -7.941 -31.105 0.017 1.00 28.14 ? 288 HIS A C 1 ATOM 2182 O O . HIS A 1 288 ? -6.890 -31.532 0.513 1.00 33.96 ? 288 HIS A O 1 ATOM 2183 C CB . HIS A 1 288 ? -10.023 -32.031 1.083 1.00 28.41 ? 288 HIS A CB 1 ATOM 2184 C CG . HIS A 1 288 ? -10.838 -31.994 2.335 1.00 29.89 ? 288 HIS A CG 1 ATOM 2185 N ND1 . HIS A 1 288 ? -12.162 -31.611 2.354 1.00 35.41 ? 288 HIS A ND1 1 ATOM 2186 C CD2 . HIS A 1 288 ? -10.499 -32.238 3.622 1.00 36.47 ? 288 HIS A CD2 1 ATOM 2187 C CE1 . HIS A 1 288 ? -12.610 -31.641 3.596 1.00 33.11 ? 288 HIS A CE1 1 ATOM 2188 N NE2 . HIS A 1 288 ? -11.620 -32.017 4.385 1.00 39.10 ? 288 HIS A NE2 1 ATOM 2189 N N . LYS A 1 289 ? -8.077 -30.880 -1.287 1.00 23.73 ? 289 LYS A N 1 ATOM 2190 C CA . LYS A 1 289 ? -6.968 -31.106 -2.208 1.00 27.17 ? 289 LYS A CA 1 ATOM 2191 C C . LYS A 1 289 ? -5.833 -30.115 -1.966 1.00 32.64 ? 289 LYS A C 1 ATOM 2192 O O . LYS A 1 289 ? -4.656 -30.493 -1.972 1.00 30.67 ? 289 LYS A O 1 ATOM 2193 C CB . LYS A 1 289 ? -7.471 -31.011 -3.649 1.00 30.31 ? 289 LYS A CB 1 ATOM 2194 C CG . LYS A 1 289 ? -6.442 -31.415 -4.696 1.00 39.75 ? 289 LYS A CG 1 ATOM 2195 C CD . LYS A 1 289 ? -5.846 -32.790 -4.371 1.00 47.13 ? 289 LYS A CD 1 ATOM 2196 C CE . LYS A 1 289 ? -4.876 -33.254 -5.449 1.00 46.21 ? 289 LYS A CE 1 ATOM 2197 N NZ . LYS A 1 289 ? -5.590 -33.544 -6.723 1.00 51.19 ? 289 LYS A NZ 1 ATOM 2198 N N . LEU A 1 290 ? -6.168 -28.844 -1.742 1.00 29.50 ? 290 LEU A N 1 ATOM 2199 C CA . LEU A 1 290 ? -5.149 -27.828 -1.525 1.00 25.17 ? 290 LEU A CA 1 ATOM 2200 C C . LEU A 1 290 ? -4.581 -27.861 -0.115 1.00 27.70 ? 290 LEU A C 1 ATOM 2201 O O . LEU A 1 290 ? -3.468 -27.374 0.086 1.00 29.98 ? 290 LEU A O 1 ATOM 2202 C CB . LEU A 1 290 ? -5.723 -26.439 -1.841 1.00 24.11 ? 290 LEU A CB 1 ATOM 2203 C CG . LEU A 1 290 ? -6.143 -26.270 -3.300 1.00 27.68 ? 290 LEU A CG 1 ATOM 2204 C CD1 . LEU A 1 290 ? -6.706 -24.878 -3.559 1.00 26.10 ? 290 LEU A CD1 1 ATOM 2205 C CD2 . LEU A 1 290 ? -4.978 -26.577 -4.249 1.00 31.02 ? 290 LEU A CD2 1 ATOM 2206 N N . ARG A 1 291 ? -5.305 -28.450 0.853 1.00 26.30 ? 291 ARG A N 1 ATOM 2207 C CA . ARG A 1 291 ? -4.789 -28.598 2.213 1.00 35.22 ? 291 ARG A CA 1 ATOM 2208 C C . ARG A 1 291 ? -3.516 -29.427 2.255 1.00 32.89 ? 291 ARG A C 1 ATOM 2209 O O . ARG A 1 291 ? -2.740 -29.316 3.209 1.00 33.87 ? 291 ARG A O 1 ATOM 2210 C CB . ARG A 1 291 ? -5.826 -29.257 3.125 1.00 36.40 ? 291 ARG A CB 1 ATOM 2211 C CG . ARG A 1 291 ? -6.815 -28.307 3.765 1.00 41.20 ? 291 ARG A CG 1 ATOM 2212 C CD . ARG A 1 291 ? -6.115 -27.260 4.605 1.00 42.89 ? 291 ARG A CD 1 ATOM 2213 N NE . ARG A 1 291 ? -6.098 -27.552 6.031 1.00 51.85 ? 291 ARG A NE 1 ATOM 2214 C CZ . ARG A 1 291 ? -5.889 -26.633 6.968 1.00 62.59 ? 291 ARG A CZ 1 ATOM 2215 N NH1 . ARG A 1 291 ? -5.886 -26.981 8.250 1.00 61.99 ? 291 ARG A NH1 1 ATOM 2216 N NH2 . ARG A 1 291 ? -5.693 -25.360 6.623 1.00 43.07 ? 291 ARG A NH2 1 ATOM 2217 N N . THR A 1 292 ? -3.294 -30.269 1.246 1.00 34.82 ? 292 THR A N 1 ATOM 2218 C CA . THR A 1 292 ? -2.133 -31.148 1.228 1.00 40.73 ? 292 THR A CA 1 ATOM 2219 C C . THR A 1 292 ? -0.880 -30.456 0.707 1.00 43.63 ? 292 THR A C 1 ATOM 2220 O O . THR A 1 292 ? 0.221 -30.997 0.864 1.00 41.86 ? 292 THR A O 1 ATOM 2221 C CB . THR A 1 292 ? -2.420 -32.384 0.366 1.00 38.42 ? 292 THR A CB 1 ATOM 2222 O OG1 . THR A 1 292 ? -2.433 -32.009 -1.016 1.00 37.85 ? 292 THR A OG1 1 ATOM 2223 C CG2 . THR A 1 292 ? -3.776 -32.988 0.725 1.00 40.08 ? 292 THR A CG2 1 ATOM 2224 N N . VAL A 1 293 ? -1.020 -29.275 0.112 1.00 35.32 ? 293 VAL A N 1 ATOM 2225 C CA . VAL A 1 293 ? 0.085 -28.623 -0.582 1.00 30.81 ? 293 VAL A CA 1 ATOM 2226 C C . VAL A 1 293 ? 0.999 -27.949 0.437 1.00 34.68 ? 293 VAL A C 1 ATOM 2227 O O . VAL A 1 293 ? 0.569 -27.063 1.185 1.00 30.50 ? 293 VAL A O 1 ATOM 2228 C CB . VAL A 1 293 ? -0.444 -27.615 -1.614 1.00 28.38 ? 293 VAL A CB 1 ATOM 2229 C CG1 . VAL A 1 293 ? 0.695 -27.034 -2.433 1.00 30.41 ? 293 VAL A CG1 1 ATOM 2230 C CG2 . VAL A 1 293 ? -1.458 -28.292 -2.529 1.00 34.79 ? 293 VAL A CG2 1 ATOM 2231 N N . GLU A 1 294 ? 2.262 -28.375 0.474 1.00 30.39 ? 294 GLU A N 1 ATOM 2232 C CA . GLU A 1 294 ? 3.244 -27.743 1.342 1.00 31.59 ? 294 GLU A CA 1 ATOM 2233 C C . GLU A 1 294 ? 3.581 -26.332 0.861 1.00 30.77 ? 294 GLU A C 1 ATOM 2234 O O . GLU A 1 294 ? 3.492 -26.022 -0.330 1.00 27.65 ? 294 GLU A O 1 ATOM 2235 C CB . GLU A 1 294 ? 4.523 -28.573 1.399 1.00 35.79 ? 294 GLU A CB 1 ATOM 2236 C CG . GLU A 1 294 ? 4.347 -29.945 2.015 1.00 47.65 ? 294 GLU A CG 1 ATOM 2237 C CD . GLU A 1 294 ? 5.638 -30.752 2.020 1.00 63.53 ? 294 GLU A CD 1 ATOM 2238 O OE1 . GLU A 1 294 ? 6.685 -30.216 1.581 1.00 56.64 ? 294 GLU A OE1 1 ATOM 2239 O OE2 . GLU A 1 294 ? 5.603 -31.922 2.460 1.00 66.38 ? 294 GLU A OE2 1 ATOM 2240 N N . HIS A 1 295 ? 3.972 -25.485 1.814 1.00 25.63 ? 295 HIS A N 1 ATOM 2241 C CA . HIS A 1 295 ? 4.474 -24.121 1.625 1.00 27.95 ? 295 HIS A CA 1 ATOM 2242 C C . HIS A 1 295 ? 3.372 -23.111 1.344 1.00 28.50 ? 295 HIS A C 1 ATOM 2243 O O . HIS A 1 295 ? 3.666 -21.965 0.960 1.00 27.11 ? 295 HIS A O 1 ATOM 2244 C CB . HIS A 1 295 ? 5.549 -24.056 0.541 1.00 24.78 ? 295 HIS A CB 1 ATOM 2245 C CG . HIS A 1 295 ? 6.658 -25.032 0.775 1.00 30.19 ? 295 HIS A CG 1 ATOM 2246 N ND1 . HIS A 1 295 ? 7.493 -24.947 1.866 1.00 30.00 ? 295 HIS A ND1 1 ATOM 2247 C CD2 . HIS A 1 295 ? 7.038 -26.137 0.092 1.00 34.21 ? 295 HIS A CD2 1 ATOM 2248 C CE1 . HIS A 1 295 ? 8.358 -25.946 1.832 1.00 35.29 ? 295 HIS A CE1 1 ATOM 2249 N NE2 . HIS A 1 295 ? 8.106 -26.681 0.764 1.00 35.92 ? 295 HIS A NE2 1 ATOM 2250 N N . MET A 1 296 ? 2.120 -23.482 1.573 1.00 26.98 ? 296 MET A N 1 ATOM 2251 C CA . MET A 1 296 ? 1.037 -22.514 1.631 1.00 28.73 ? 296 MET A CA 1 ATOM 2252 C C . MET A 1 296 ? 0.014 -23.017 2.635 1.00 33.07 ? 296 MET A C 1 ATOM 2253 O O . MET A 1 296 ? 0.090 -24.151 3.115 1.00 27.70 ? 296 MET A O 1 ATOM 2254 C CB . MET A 1 296 ? 0.408 -22.289 0.256 1.00 25.57 ? 296 MET A CB 1 ATOM 2255 C CG . MET A 1 296 ? -0.325 -23.499 -0.305 1.00 29.06 ? 296 MET A CG 1 ATOM 2256 S SD . MET A 1 296 ? -1.304 -22.989 -1.724 1.00 29.69 ? 296 MET A SD 1 ATOM 2257 C CE . MET A 1 296 ? -2.396 -24.408 -1.915 1.00 34.12 ? 296 MET A CE 1 ATOM 2258 N N . THR A 1 297 ? -0.941 -22.151 2.962 1.00 23.42 ? 297 THR A N 1 ATOM 2259 C CA . THR A 1 297 ? -2.059 -22.495 3.824 1.00 25.18 ? 297 THR A CA 1 ATOM 2260 C C . THR A 1 297 ? -3.341 -22.094 3.111 1.00 31.40 ? 297 THR A C 1 ATOM 2261 O O . THR A 1 297 ? -3.418 -20.993 2.559 1.00 26.80 ? 297 THR A O 1 ATOM 2262 C CB . THR A 1 297 ? -1.959 -21.786 5.182 1.00 25.25 ? 297 THR A CB 1 ATOM 2263 O OG1 . THR A 1 297 ? -0.687 -22.070 5.779 1.00 28.21 ? 297 THR A OG1 1 ATOM 2264 C CG2 . THR A 1 297 ? -3.066 -22.253 6.110 1.00 25.93 ? 297 THR A CG2 1 ATOM 2265 N N . VAL A 1 298 ? -4.335 -22.981 3.092 1.00 25.07 ? 298 VAL A N 1 ATOM 2266 C CA . VAL A 1 298 ? -5.649 -22.651 2.551 1.00 23.89 ? 298 VAL A CA 1 ATOM 2267 C C . VAL A 1 298 ? -6.605 -22.491 3.722 1.00 27.06 ? 298 VAL A C 1 ATOM 2268 O O . VAL A 1 298 ? -6.622 -23.315 4.644 1.00 26.11 ? 298 VAL A O 1 ATOM 2269 C CB . VAL A 1 298 ? -6.147 -23.692 1.528 1.00 31.10 ? 298 VAL A CB 1 ATOM 2270 C CG1 . VAL A 1 298 ? -6.099 -25.069 2.076 1.00 36.53 ? 298 VAL A CG1 1 ATOM 2271 C CG2 . VAL A 1 298 ? -7.572 -23.361 1.045 1.00 27.38 ? 298 VAL A CG2 1 ATOM 2272 N N . TYR A 1 299 ? -7.376 -21.405 3.702 1.00 24.86 ? 299 TYR A N 1 ATOM 2273 C CA . TYR A 1 299 ? -8.328 -21.095 4.755 1.00 23.36 ? 299 TYR A CA 1 ATOM 2274 C C . TYR A 1 299 ? -9.727 -20.985 4.174 1.00 26.41 ? 299 TYR A C 1 ATOM 2275 O O . TYR A 1 299 ? -9.936 -20.292 3.172 1.00 26.03 ? 299 TYR A O 1 ATOM 2276 C CB . TYR A 1 299 ? -8.021 -19.762 5.450 1.00 24.52 ? 299 TYR A CB 1 ATOM 2277 C CG . TYR A 1 299 ? -6.677 -19.643 6.112 1.00 26.60 ? 299 TYR A CG 1 ATOM 2278 C CD1 . TYR A 1 299 ? -6.428 -20.265 7.330 1.00 23.08 ? 299 TYR A CD1 1 ATOM 2279 C CD2 . TYR A 1 299 ? -5.668 -18.874 5.539 1.00 27.50 ? 299 TYR A CD2 1 ATOM 2280 C CE1 . TYR A 1 299 ? -5.201 -20.145 7.949 1.00 29.36 ? 299 TYR A CE1 1 ATOM 2281 C CE2 . TYR A 1 299 ? -4.441 -18.739 6.159 1.00 29.04 ? 299 TYR A CE2 1 ATOM 2282 C CZ . TYR A 1 299 ? -4.216 -19.386 7.361 1.00 29.51 ? 299 TYR A CZ 1 ATOM 2283 O OH . TYR A 1 299 ? -3.002 -19.272 7.995 1.00 30.97 ? 299 TYR A OH 1 ATOM 2284 N N . GLU A 1 300 ? -10.676 -21.637 4.830 1.00 25.87 ? 300 GLU A N 1 ATOM 2285 C CA . GLU A 1 300 ? -12.067 -21.255 4.701 1.00 24.28 ? 300 GLU A CA 1 ATOM 2286 C C . GLU A 1 300 ? -12.271 -19.896 5.350 1.00 24.69 ? 300 GLU A C 1 ATOM 2287 O O . GLU A 1 300 ? -11.597 -19.542 6.320 1.00 26.72 ? 300 GLU A O 1 ATOM 2288 C CB . GLU A 1 300 ? -12.970 -22.298 5.356 1.00 31.00 ? 300 GLU A CB 1 ATOM 2289 C CG . GLU A 1 300 ? -12.943 -23.638 4.651 1.00 32.79 ? 300 GLU A CG 1 ATOM 2290 C CD . GLU A 1 300 ? -13.897 -24.632 5.276 1.00 44.07 ? 300 GLU A CD 1 ATOM 2291 O OE1 . GLU A 1 300 ? -13.741 -24.932 6.479 1.00 50.77 ? 300 GLU A OE1 1 ATOM 2292 O OE2 . GLU A 1 300 ? -14.813 -25.097 4.568 1.00 43.98 ? 300 GLU A OE2 1 ATOM 2293 N N . LYS A 1 301 ? -13.202 -19.124 4.792 1.00 25.86 ? 301 LYS A N 1 ATOM 2294 C CA . LYS A 1 301 ? -13.379 -17.744 5.234 1.00 31.12 ? 301 LYS A CA 1 ATOM 2295 C C . LYS A 1 301 ? -13.557 -17.672 6.748 1.00 31.10 ? 301 LYS A C 1 ATOM 2296 O O . LYS A 1 301 ? -12.951 -16.827 7.416 1.00 25.53 ? 301 LYS A O 1 ATOM 2297 C CB . LYS A 1 301 ? -14.564 -17.115 4.490 1.00 24.71 ? 301 LYS A CB 1 ATOM 2298 C CG . LYS A 1 301 ? -14.795 -15.634 4.768 1.00 28.08 ? 301 LYS A CG 1 ATOM 2299 C CD . LYS A 1 301 ? -15.761 -15.012 3.738 1.00 27.27 ? 301 LYS A CD 1 ATOM 2300 C CE . LYS A 1 301 ? -16.046 -13.528 4.034 1.00 30.74 ? 301 LYS A CE 1 ATOM 2301 N NZ . LYS A 1 301 ? -16.816 -12.829 2.933 1.00 32.90 ? 301 LYS A NZ 1 ATOM 2302 N N . GLU A 1 302 ? -14.325 -18.602 7.323 1.00 27.68 ? 302 GLU A N 1 ATOM 2303 C CA . GLU A 1 302 ? -14.554 -18.543 8.763 1.00 31.84 ? 302 GLU A CA 1 ATOM 2304 C C . GLU A 1 302 ? -13.338 -18.961 9.586 1.00 32.91 ? 302 GLU A C 1 ATOM 2305 O O . GLU A 1 302 ? -13.306 -18.680 10.784 1.00 35.97 ? 302 GLU A O 1 ATOM 2306 C CB . GLU A 1 302 ? -15.761 -19.407 9.145 1.00 38.59 ? 302 GLU A CB 1 ATOM 2307 N N . SER A 1 303 ? -12.332 -19.588 8.983 1.00 28.65 ? 303 SER A N 1 ATOM 2308 C CA . SER A 1 303 ? -11.160 -20.053 9.715 1.00 29.10 ? 303 SER A CA 1 ATOM 2309 C C . SER A 1 303 ? -9.922 -19.184 9.509 1.00 26.44 ? 303 SER A C 1 ATOM 2310 O O . SER A 1 303 ? -8.849 -19.523 10.018 1.00 26.08 ? 303 SER A O 1 ATOM 2311 C CB . SER A 1 303 ? -10.852 -21.499 9.320 1.00 33.71 ? 303 SER A CB 1 ATOM 2312 O OG . SER A 1 303 ? -11.903 -22.357 9.734 1.00 40.07 ? 303 SER A OG 1 ATOM 2313 N N . ILE A 1 304 ? -10.036 -18.094 8.756 1.00 24.17 ? 304 ILE A N 1 ATOM 2314 C CA . ILE A 1 304 ? -8.909 -17.176 8.563 1.00 26.11 ? 304 ILE A CA 1 ATOM 2315 C C . ILE A 1 304 ? -8.466 -16.648 9.920 1.00 23.52 ? 304 ILE A C 1 ATOM 2316 O O . ILE A 1 304 ? -9.327 -16.316 10.755 1.00 24.65 ? 304 ILE A O 1 ATOM 2317 C CB . ILE A 1 304 ? -9.316 -16.020 7.629 1.00 21.09 ? 304 ILE A CB 1 ATOM 2318 C CG1 . ILE A 1 304 ? -9.511 -16.537 6.194 1.00 20.66 ? 304 ILE A CG1 1 ATOM 2319 C CG2 . ILE A 1 304 ? -8.299 -14.885 7.701 1.00 21.01 ? 304 ILE A CG2 1 ATOM 2320 C CD1 . ILE A 1 304 ? -10.198 -15.535 5.271 1.00 20.22 ? 304 ILE A CD1 1 ATOM 2321 N N . PRO A 1 305 ? -7.165 -16.565 10.207 1.00 22.89 ? 305 PRO A N 1 ATOM 2322 C CA . PRO A 1 305 ? -6.724 -16.090 11.527 1.00 27.91 ? 305 PRO A CA 1 ATOM 2323 C C . PRO A 1 305 ? -7.331 -14.737 11.877 1.00 28.27 ? 305 PRO A C 1 ATOM 2324 O O . PRO A 1 305 ? -7.335 -13.805 11.065 1.00 23.10 ? 305 PRO A O 1 ATOM 2325 C CB . PRO A 1 305 ? -5.202 -16.005 11.376 1.00 29.53 ? 305 PRO A CB 1 ATOM 2326 C CG . PRO A 1 305 ? -4.877 -17.017 10.298 1.00 27.74 ? 305 PRO A CG 1 ATOM 2327 C CD . PRO A 1 305 ? -6.029 -16.927 9.342 1.00 26.28 ? 305 PRO A CD 1 ATOM 2328 N N . ASN A 1 306 ? -7.861 -14.632 13.100 1.00 23.68 ? 306 ASN A N 1 ATOM 2329 C CA . ASN A 1 306 ? -8.500 -13.382 13.504 1.00 23.14 ? 306 ASN A CA 1 ATOM 2330 C C . ASN A 1 306 ? -7.511 -12.225 13.492 1.00 25.68 ? 306 ASN A C 1 ATOM 2331 O O . ASN A 1 306 ? -7.897 -11.075 13.266 1.00 24.41 ? 306 ASN A O 1 ATOM 2332 C CB . ASN A 1 306 ? -9.106 -13.512 14.901 1.00 21.98 ? 306 ASN A CB 1 ATOM 2333 C CG . ASN A 1 306 ? -10.292 -14.456 14.946 1.00 31.76 ? 306 ASN A CG 1 ATOM 2334 O OD1 . ASN A 1 306 ? -10.988 -14.659 13.947 1.00 28.04 ? 306 ASN A OD1 1 ATOM 2335 N ND2 . ASN A 1 306 ? -10.547 -15.015 16.128 1.00 31.69 ? 306 ASN A ND2 1 ATOM 2336 N N . ARG A 1 307 ? -6.233 -12.506 13.745 1.00 21.98 ? 307 ARG A N 1 ATOM 2337 C CA . ARG A 1 307 ? -5.250 -11.432 13.819 1.00 25.53 ? 307 ARG A CA 1 ATOM 2338 C C . ARG A 1 307 ? -5.068 -10.701 12.489 1.00 23.72 ? 307 ARG A C 1 ATOM 2339 O O . ARG A 1 307 ? -4.512 -9.598 12.479 1.00 21.56 ? 307 ARG A O 1 ATOM 2340 C CB . ARG A 1 307 ? -3.906 -11.983 14.299 1.00 23.96 ? 307 ARG A CB 1 ATOM 2341 C CG . ARG A 1 307 ? -3.199 -12.906 13.321 1.00 22.54 ? 307 ARG A CG 1 ATOM 2342 C CD . ARG A 1 307 ? -1.793 -13.221 13.842 1.00 24.31 ? 307 ARG A CD 1 ATOM 2343 N NE . ARG A 1 307 ? -1.126 -14.288 13.101 1.00 24.93 ? 307 ARG A NE 1 ATOM 2344 C CZ . ARG A 1 307 ? -0.215 -14.099 12.149 1.00 27.23 ? 307 ARG A CZ 1 ATOM 2345 N NH1 . ARG A 1 307 ? 0.130 -12.865 11.774 1.00 27.03 ? 307 ARG A NH1 1 ATOM 2346 N NH2 . ARG A 1 307 ? 0.341 -15.153 11.559 1.00 27.11 ? 307 ARG A NH2 1 ATOM 2347 N N . PHE A 1 308 ? -5.524 -11.278 11.377 1.00 24.44 ? 308 PHE A N 1 ATOM 2348 C CA . PHE A 1 308 ? -5.445 -10.599 10.085 1.00 21.45 ? 308 PHE A CA 1 ATOM 2349 C C . PHE A 1 308 ? -6.474 -9.486 9.916 1.00 21.86 ? 308 PHE A C 1 ATOM 2350 O O . PHE A 1 308 ? -6.331 -8.678 8.987 1.00 21.40 ? 308 PHE A O 1 ATOM 2351 C CB . PHE A 1 308 ? -5.624 -11.613 8.950 1.00 18.30 ? 308 PHE A CB 1 ATOM 2352 C CG . PHE A 1 308 ? -4.437 -12.515 8.735 1.00 25.02 ? 308 PHE A CG 1 ATOM 2353 C CD1 . PHE A 1 308 ? -3.187 -12.197 9.261 1.00 24.73 ? 308 PHE A CD1 1 ATOM 2354 C CD2 . PHE A 1 308 ? -4.568 -13.673 7.985 1.00 26.56 ? 308 PHE A CD2 1 ATOM 2355 C CE1 . PHE A 1 308 ? -2.083 -13.035 9.042 1.00 28.96 ? 308 PHE A CE1 1 ATOM 2356 C CE2 . PHE A 1 308 ? -3.479 -14.512 7.764 1.00 30.79 ? 308 PHE A CE2 1 ATOM 2357 C CZ . PHE A 1 308 ? -2.233 -14.189 8.291 1.00 27.18 ? 308 PHE A CZ 1 ATOM 2358 N N . TYR A 1 309 ? -7.497 -9.426 10.772 1.00 22.00 ? 309 TYR A N 1 ATOM 2359 C CA . TYR A 1 309 ? -8.594 -8.454 10.660 1.00 19.26 ? 309 TYR A CA 1 ATOM 2360 C C . TYR A 1 309 ? -9.067 -8.317 9.217 1.00 20.88 ? 309 TYR A C 1 ATOM 2361 O O . TYR A 1 309 ? -9.237 -7.216 8.683 1.00 20.93 ? 309 TYR A O 1 ATOM 2362 C CB . TYR A 1 309 ? -8.189 -7.094 11.234 1.00 20.99 ? 309 TYR A CB 1 ATOM 2363 C CG . TYR A 1 309 ? -7.896 -7.175 12.706 1.00 26.90 ? 309 TYR A CG 1 ATOM 2364 C CD1 . TYR A 1 309 ? -8.934 -7.276 13.633 1.00 30.24 ? 309 TYR A CD1 1 ATOM 2365 C CD2 . TYR A 1 309 ? -6.586 -7.190 13.174 1.00 29.11 ? 309 TYR A CD2 1 ATOM 2366 C CE1 . TYR A 1 309 ? -8.664 -7.374 15.009 1.00 30.96 ? 309 TYR A CE1 1 ATOM 2367 C CE2 . TYR A 1 309 ? -6.312 -7.293 14.532 1.00 31.22 ? 309 TYR A CE2 1 ATOM 2368 C CZ . TYR A 1 309 ? -7.354 -7.383 15.444 1.00 35.26 ? 309 TYR A CZ 1 ATOM 2369 O OH . TYR A 1 309 ? -7.076 -7.472 16.799 1.00 33.19 ? 309 TYR A OH 1 ATOM 2370 N N . TYR A 1 310 ? -9.310 -9.458 8.603 1.00 18.46 ? 310 TYR A N 1 ATOM 2371 C CA . TYR A 1 310 ? -9.578 -9.617 7.180 1.00 18.00 ? 310 TYR A CA 1 ATOM 2372 C C . TYR A 1 310 ? -10.852 -10.396 6.890 1.00 19.74 ? 310 TYR A C 1 ATOM 2373 O O . TYR A 1 310 ? -11.593 -10.032 5.961 1.00 21.70 ? 310 TYR A O 1 ATOM 2374 C CB . TYR A 1 310 ? -8.339 -10.322 6.580 1.00 20.39 ? 310 TYR A CB 1 ATOM 2375 C CG . TYR A 1 310 ? -8.394 -10.752 5.126 1.00 21.45 ? 310 TYR A CG 1 ATOM 2376 C CD1 . TYR A 1 310 ? -7.967 -9.898 4.105 1.00 17.88 ? 310 TYR A CD1 1 ATOM 2377 C CD2 . TYR A 1 310 ? -8.804 -12.037 4.776 1.00 19.64 ? 310 TYR A CD2 1 ATOM 2378 C CE1 . TYR A 1 310 ? -7.973 -10.307 2.779 1.00 19.39 ? 310 TYR A CE1 1 ATOM 2379 C CE2 . TYR A 1 310 ? -8.819 -12.453 3.440 1.00 19.55 ? 310 TYR A CE2 1 ATOM 2380 C CZ . TYR A 1 310 ? -8.397 -11.578 2.452 1.00 20.88 ? 310 TYR A CZ 1 ATOM 2381 O OH . TYR A 1 310 ? -8.390 -11.967 1.131 1.00 20.59 ? 310 TYR A OH 1 ATOM 2382 N N . LYS A 1 311 ? -11.149 -11.439 7.686 1.00 19.54 ? 311 LYS A N 1 ATOM 2383 C CA . LYS A 1 311 ? -12.153 -12.445 7.328 1.00 18.18 ? 311 LYS A CA 1 ATOM 2384 C C . LYS A 1 311 ? -13.573 -11.892 7.229 1.00 21.68 ? 311 LYS A C 1 ATOM 2385 O O . LYS A 1 311 ? -14.392 -12.475 6.513 1.00 24.48 ? 311 LYS A O 1 ATOM 2386 C CB . LYS A 1 311 ? -12.137 -13.598 8.339 1.00 21.37 ? 311 LYS A CB 1 ATOM 2387 C CG . LYS A 1 311 ? -12.677 -13.213 9.719 1.00 23.09 ? 311 LYS A CG 1 ATOM 2388 C CD . LYS A 1 311 ? -12.141 -14.137 10.811 1.00 27.29 ? 311 LYS A CD 1 ATOM 2389 C CE . LYS A 1 311 ? -12.631 -15.555 10.657 1.00 26.18 ? 311 LYS A CE 1 ATOM 2390 N NZ . LYS A 1 311 ? -11.869 -16.448 11.610 1.00 24.58 ? 311 LYS A NZ 1 ATOM 2391 N N . LYS A 1 312 ? -13.886 -10.788 7.912 1.00 21.42 ? 312 LYS A N 1 ATOM 2392 C CA . LYS A 1 312 ? -15.230 -10.221 7.852 1.00 24.32 ? 312 LYS A CA 1 ATOM 2393 C C . LYS A 1 312 ? -15.495 -9.379 6.599 1.00 25.74 ? 312 LYS A C 1 ATOM 2394 O O . LYS A 1 312 ? -16.631 -8.913 6.424 1.00 24.54 ? 312 LYS A O 1 ATOM 2395 C CB . LYS A 1 312 ? -15.502 -9.365 9.096 1.00 20.72 ? 312 LYS A CB 1 ATOM 2396 C CG . LYS A 1 312 ? -15.474 -10.115 10.434 1.00 26.88 ? 312 LYS A CG 1 ATOM 2397 C CD . LYS A 1 312 ? -15.800 -9.135 11.558 1.00 29.86 ? 312 LYS A CD 1 ATOM 2398 C CE . LYS A 1 312 ? -15.828 -9.795 12.925 1.00 42.62 ? 312 LYS A CE 1 ATOM 2399 N NZ . LYS A 1 312 ? -16.242 -8.795 13.957 1.00 58.71 ? 312 LYS A NZ 1 ATOM 2400 N N . GLY A 1 313 ? -14.507 -9.168 5.729 1.00 20.83 ? 313 GLY A N 1 ATOM 2401 C CA . GLY A 1 313 ? -14.745 -8.343 4.552 1.00 19.18 ? 313 GLY A CA 1 ATOM 2402 C C . GLY A 1 313 ? -15.733 -8.998 3.599 1.00 19.96 ? 313 GLY A C 1 ATOM 2403 O O . GLY A 1 313 ? -15.692 -10.205 3.364 1.00 20.54 ? 313 GLY A O 1 ATOM 2404 N N . LYS A 1 314 ? -16.629 -8.189 3.029 1.00 21.33 ? 314 LYS A N 1 ATOM 2405 C CA . LYS A 1 314 ? -17.694 -8.788 2.233 1.00 21.66 ? 314 LYS A CA 1 ATOM 2406 C C . LYS A 1 314 ? -17.169 -9.414 0.942 1.00 23.24 ? 314 LYS A C 1 ATOM 2407 O O . LYS A 1 314 ? -17.784 -10.352 0.430 1.00 24.53 ? 314 LYS A O 1 ATOM 2408 C CB . LYS A 1 314 ? -18.795 -7.760 1.937 1.00 26.00 ? 314 LYS A CB 1 ATOM 2409 C CG . LYS A 1 314 ? -18.429 -6.616 1.021 1.00 29.96 ? 314 LYS A CG 1 ATOM 2410 C CD . LYS A 1 314 ? -19.727 -5.910 0.574 1.00 39.75 ? 314 LYS A CD 1 ATOM 2411 C CE . LYS A 1 314 ? -19.539 -4.413 0.406 1.00 45.32 ? 314 LYS A CE 1 ATOM 2412 N NZ . LYS A 1 314 ? -20.820 -3.712 0.059 1.00 48.67 ? 314 LYS A NZ 1 ATOM 2413 N N . PHE A 1 315 ? -16.052 -8.927 0.405 1.00 19.00 ? 315 PHE A N 1 ATOM 2414 C CA . PHE A 1 315 ? -15.511 -9.447 -0.850 1.00 20.17 ? 315 PHE A CA 1 ATOM 2415 C C . PHE A 1 315 ? -14.544 -10.613 -0.651 1.00 22.49 ? 315 PHE A C 1 ATOM 2416 O O . PHE A 1 315 ? -14.094 -11.193 -1.648 1.00 20.08 ? 315 PHE A O 1 ATOM 2417 C CB . PHE A 1 315 ? -14.809 -8.326 -1.641 1.00 19.08 ? 315 PHE A CB 1 ATOM 2418 C CG . PHE A 1 315 ? -15.741 -7.192 -2.058 1.00 23.10 ? 315 PHE A CG 1 ATOM 2419 C CD1 . PHE A 1 315 ? -16.876 -7.459 -2.802 1.00 24.43 ? 315 PHE A CD1 1 ATOM 2420 C CD2 . PHE A 1 315 ? -15.470 -5.879 -1.697 1.00 22.94 ? 315 PHE A CD2 1 ATOM 2421 C CE1 . PHE A 1 315 ? -17.744 -6.426 -3.185 1.00 25.07 ? 315 PHE A CE1 1 ATOM 2422 C CE2 . PHE A 1 315 ? -16.326 -4.847 -2.082 1.00 26.36 ? 315 PHE A CE2 1 ATOM 2423 C CZ . PHE A 1 315 ? -17.460 -5.123 -2.817 1.00 26.97 ? 315 PHE A CZ 1 ATOM 2424 N N . VAL A 1 316 ? -14.212 -10.954 0.602 1.00 19.07 ? 316 VAL A N 1 ATOM 2425 C CA . VAL A 1 316 ? -13.311 -12.078 0.863 1.00 23.39 ? 316 VAL A CA 1 ATOM 2426 C C . VAL A 1 316 ? -13.941 -13.350 0.306 1.00 20.50 ? 316 VAL A C 1 ATOM 2427 O O . VAL A 1 316 ? -15.151 -13.565 0.425 1.00 19.68 ? 316 VAL A O 1 ATOM 2428 C CB . VAL A 1 316 ? -13.022 -12.200 2.370 1.00 21.64 ? 316 VAL A CB 1 ATOM 2429 C CG1 . VAL A 1 316 ? -12.352 -13.563 2.730 1.00 20.68 ? 316 VAL A CG1 1 ATOM 2430 C CG2 . VAL A 1 316 ? -12.146 -11.040 2.853 1.00 20.61 ? 316 VAL A CG2 1 ATOM 2431 N N . SER A 1 317 ? -13.125 -14.171 -0.357 1.00 21.98 ? 317 SER A N 1 ATOM 2432 C CA . SER A 1 317 ? -13.595 -15.336 -1.096 1.00 22.73 ? 317 SER A CA 1 ATOM 2433 C C . SER A 1 317 ? -13.836 -16.533 -0.172 1.00 21.88 ? 317 SER A C 1 ATOM 2434 O O . SER A 1 317 ? -13.395 -16.540 0.978 1.00 23.10 ? 317 SER A O 1 ATOM 2435 C CB . SER A 1 317 ? -12.581 -15.697 -2.177 1.00 22.21 ? 317 SER A CB 1 ATOM 2436 O OG . SER A 1 317 ? -11.292 -15.917 -1.616 1.00 21.00 ? 317 SER A OG 1 ATOM 2437 N N . PRO A 1 318 ? -14.573 -17.553 -0.643 1.00 19.48 ? 318 PRO A N 1 ATOM 2438 C CA . PRO A 1 318 ? -14.776 -18.749 0.197 1.00 23.10 ? 318 PRO A CA 1 ATOM 2439 C C . PRO A 1 318 ? -13.482 -19.420 0.613 1.00 23.20 ? 318 PRO A C 1 ATOM 2440 O O . PRO A 1 318 ? -13.377 -19.884 1.752 1.00 25.80 ? 318 PRO A O 1 ATOM 2441 C CB . PRO A 1 318 ? -15.626 -19.671 -0.693 1.00 25.04 ? 318 PRO A CB 1 ATOM 2442 C CG . PRO A 1 318 ? -16.369 -18.716 -1.610 1.00 24.53 ? 318 PRO A CG 1 ATOM 2443 C CD . PRO A 1 318 ? -15.377 -17.601 -1.879 1.00 24.94 ? 318 PRO A CD 1 ATOM 2444 N N . LEU A 1 319 ? -12.498 -19.487 -0.276 1.00 22.96 ? 319 LEU A N 1 ATOM 2445 C CA . LEU A 1 319 ? -11.186 -20.033 0.045 1.00 23.51 ? 319 LEU A CA 1 ATOM 2446 C C . LEU A 1 319 ? -10.130 -18.981 -0.242 1.00 24.38 ? 319 LEU A C 1 ATOM 2447 O O . LEU A 1 319 ? -10.187 -18.297 -1.271 1.00 22.06 ? 319 LEU A O 1 ATOM 2448 C CB . LEU A 1 319 ? -10.897 -21.299 -0.774 1.00 22.89 ? 319 LEU A CB 1 ATOM 2449 C CG . LEU A 1 319 ? -11.858 -22.467 -0.541 1.00 28.64 ? 319 LEU A CG 1 ATOM 2450 C CD1 . LEU A 1 319 ? -11.480 -23.643 -1.439 1.00 24.74 ? 319 LEU A CD1 1 ATOM 2451 C CD2 . LEU A 1 319 ? -11.879 -22.891 0.924 1.00 26.28 ? 319 LEU A CD2 1 ATOM 2452 N N . THR A 1 320 ? -9.174 -18.841 0.669 1.00 22.20 ? 320 THR A N 1 ATOM 2453 C CA . THR A 1 320 ? -8.062 -17.924 0.472 1.00 23.20 ? 320 THR A CA 1 ATOM 2454 C C . THR A 1 320 ? -6.763 -18.677 0.708 1.00 20.60 ? 320 THR A C 1 ATOM 2455 O O . THR A 1 320 ? -6.613 -19.361 1.726 1.00 23.42 ? 320 THR A O 1 ATOM 2456 C CB . THR A 1 320 ? -8.160 -16.702 1.399 1.00 21.96 ? 320 THR A CB 1 ATOM 2457 O OG1 . THR A 1 320 ? -9.431 -16.071 1.217 1.00 22.93 ? 320 THR A OG1 1 ATOM 2458 C CG2 . THR A 1 320 ? -7.051 -15.696 1.071 1.00 21.63 ? 320 THR A CG2 1 ATOM 2459 N N . LEU A 1 321 ? -5.853 -18.576 -0.250 1.00 21.17 ? 321 LEU A N 1 ATOM 2460 C CA . LEU A 1 321 ? -4.541 -19.211 -0.179 1.00 19.07 ? 321 LEU A CA 1 ATOM 2461 C C . LEU A 1 321 ? -3.514 -18.194 0.298 1.00 23.79 ? 321 LEU A C 1 ATOM 2462 O O . LEU A 1 321 ? -3.458 -17.075 -0.222 1.00 21.41 ? 321 LEU A O 1 ATOM 2463 C CB . LEU A 1 321 ? -4.133 -19.740 -1.553 1.00 20.01 ? 321 LEU A CB 1 ATOM 2464 C CG . LEU A 1 321 ? -5.129 -20.628 -2.286 1.00 25.11 ? 321 LEU A CG 1 ATOM 2465 C CD1 . LEU A 1 321 ? -4.596 -20.972 -3.675 1.00 25.73 ? 321 LEU A CD1 1 ATOM 2466 C CD2 . LEU A 1 321 ? -5.326 -21.872 -1.483 1.00 30.25 ? 321 LEU A CD2 1 ATOM 2467 N N . VAL A 1 322 ? -2.682 -18.584 1.262 1.00 21.26 ? 322 VAL A N 1 ATOM 2468 C CA . VAL A 1 322 ? -1.632 -17.703 1.773 1.00 21.28 ? 322 VAL A CA 1 ATOM 2469 C C . VAL A 1 322 ? -0.320 -18.457 1.692 1.00 22.21 ? 322 VAL A C 1 ATOM 2470 O O . VAL A 1 322 ? -0.129 -19.454 2.403 1.00 23.27 ? 322 VAL A O 1 ATOM 2471 C CB . VAL A 1 322 ? -1.909 -17.232 3.206 1.00 22.52 ? 322 VAL A CB 1 ATOM 2472 C CG1 . VAL A 1 322 ? -0.776 -16.293 3.692 1.00 25.12 ? 322 VAL A CG1 1 ATOM 2473 C CG2 . VAL A 1 322 ? -3.266 -16.557 3.272 1.00 21.20 ? 322 VAL A CG2 1 ATOM 2474 N N . ALA A 1 323 ? 0.577 -17.994 0.822 1.00 21.98 ? 323 ALA A N 1 ATOM 2475 C CA . ALA A 1 323 ? 1.871 -18.646 0.641 1.00 21.49 ? 323 ALA A CA 1 ATOM 2476 C C . ALA A 1 323 ? 2.827 -18.343 1.793 1.00 25.07 ? 323 ALA A C 1 ATOM 2477 O O . ALA A 1 323 ? 2.790 -17.270 2.404 1.00 21.16 ? 323 ALA A O 1 ATOM 2478 C CB . ALA A 1 323 ? 2.517 -18.204 -0.670 1.00 20.11 ? 323 ALA A CB 1 ATOM 2479 N N . ASP A 1 324 ? 3.703 -19.307 2.088 1.00 20.17 ? 324 ASP A N 1 ATOM 2480 C CA . ASP A 1 324 ? 4.820 -19.036 2.985 1.00 26.16 ? 324 ASP A CA 1 ATOM 2481 C C . ASP A 1 324 ? 5.757 -18.005 2.368 1.00 20.83 ? 324 ASP A C 1 ATOM 2482 O O . ASP A 1 324 ? 5.880 -17.907 1.147 1.00 23.06 ? 324 ASP A O 1 ATOM 2483 C CB . ASP A 1 324 ? 5.614 -20.310 3.279 1.00 26.61 ? 324 ASP A CB 1 ATOM 2484 C CG . ASP A 1 324 ? 4.820 -21.338 4.061 1.00 31.39 ? 324 ASP A CG 1 ATOM 2485 O OD1 . ASP A 1 324 ? 3.743 -21.003 4.593 1.00 31.73 ? 324 ASP A OD1 1 ATOM 2486 O OD2 . ASP A 1 324 ? 5.304 -22.491 4.157 1.00 31.95 ? 324 ASP A OD2 1 ATOM 2487 N N . GLU A 1 325 ? 6.429 -17.236 3.225 1.00 22.49 ? 325 GLU A N 1 ATOM 2488 C CA . GLU A 1 325 ? 7.345 -16.201 2.745 1.00 22.96 ? 325 GLU A CA 1 ATOM 2489 C C . GLU A 1 325 ? 8.340 -16.751 1.719 1.00 27.60 ? 325 GLU A C 1 ATOM 2490 O O . GLU A 1 325 ? 8.994 -17.778 1.948 1.00 25.80 ? 325 GLU A O 1 ATOM 2491 C CB . GLU A 1 325 ? 8.096 -15.589 3.930 1.00 28.30 ? 325 GLU A CB 1 ATOM 2492 C CG . GLU A 1 325 ? 8.898 -14.334 3.560 1.00 25.51 ? 325 GLU A CG 1 ATOM 2493 C CD . GLU A 1 325 ? 9.705 -13.808 4.735 1.00 31.34 ? 325 GLU A CD 1 ATOM 2494 O OE1 . GLU A 1 325 ? 10.423 -14.606 5.382 1.00 36.15 ? 325 GLU A OE1 1 ATOM 2495 O OE2 . GLU A 1 325 ? 9.597 -12.605 5.037 1.00 30.86 ? 325 GLU A OE2 1 ATOM 2496 N N . GLY A 1 326 ? 8.445 -16.059 0.580 1.00 21.69 ? 326 GLY A N 1 ATOM 2497 C CA . GLY A 1 326 ? 9.344 -16.424 -0.497 1.00 23.54 ? 326 GLY A CA 1 ATOM 2498 C C . GLY A 1 326 ? 8.749 -17.330 -1.557 1.00 21.68 ? 326 GLY A C 1 ATOM 2499 O O . GLY A 1 326 ? 9.340 -17.481 -2.637 1.00 23.42 ? 326 GLY A O 1 ATOM 2500 N N . TRP A 1 327 ? 7.604 -17.936 -1.279 1.00 23.08 ? 327 TRP A N 1 ATOM 2501 C CA . TRP A 1 327 ? 6.884 -18.782 -2.214 1.00 21.42 ? 327 TRP A CA 1 ATOM 2502 C C . TRP A 1 327 ? 5.872 -17.959 -3.002 1.00 25.85 ? 327 TRP A C 1 ATOM 2503 O O . TRP A 1 327 ? 5.460 -16.878 -2.581 1.00 26.16 ? 327 TRP A O 1 ATOM 2504 C CB . TRP A 1 327 ? 6.182 -19.902 -1.456 1.00 22.75 ? 327 TRP A CB 1 ATOM 2505 C CG . TRP A 1 327 ? 7.150 -20.913 -1.017 1.00 27.90 ? 327 TRP A CG 1 ATOM 2506 C CD1 . TRP A 1 327 ? 7.972 -20.852 0.073 1.00 26.27 ? 327 TRP A CD1 1 ATOM 2507 C CD2 . TRP A 1 327 ? 7.451 -22.129 -1.690 1.00 25.84 ? 327 TRP A CD2 1 ATOM 2508 N NE1 . TRP A 1 327 ? 8.763 -21.985 0.126 1.00 27.70 ? 327 TRP A NE1 1 ATOM 2509 C CE2 . TRP A 1 327 ? 8.456 -22.783 -0.945 1.00 29.48 ? 327 TRP A CE2 1 ATOM 2510 C CE3 . TRP A 1 327 ? 6.954 -22.743 -2.840 1.00 27.95 ? 327 TRP A CE3 1 ATOM 2511 C CZ2 . TRP A 1 327 ? 8.979 -24.013 -1.324 1.00 33.30 ? 327 TRP A CZ2 1 ATOM 2512 C CZ3 . TRP A 1 327 ? 7.470 -23.975 -3.208 1.00 30.28 ? 327 TRP A CZ3 1 ATOM 2513 C CH2 . TRP A 1 327 ? 8.471 -24.592 -2.451 1.00 30.78 ? 327 TRP A CH2 1 ATOM 2514 N N . PHE A 1 328 ? 5.461 -18.496 -4.150 1.00 24.43 ? 328 PHE A N 1 ATOM 2515 C CA . PHE A 1 328 ? 4.644 -17.758 -5.112 1.00 26.70 ? 328 PHE A CA 1 ATOM 2516 C C . PHE A 1 328 ? 3.627 -18.718 -5.711 1.00 27.36 ? 328 PHE A C 1 ATOM 2517 O O . PHE A 1 328 ? 4.013 -19.744 -6.285 1.00 29.38 ? 328 PHE A O 1 ATOM 2518 C CB . PHE A 1 328 ? 5.530 -17.148 -6.209 1.00 22.98 ? 328 PHE A CB 1 ATOM 2519 C CG . PHE A 1 328 ? 4.883 -16.015 -6.978 1.00 22.74 ? 328 PHE A CG 1 ATOM 2520 C CD1 . PHE A 1 328 ? 4.024 -16.272 -8.033 1.00 24.14 ? 328 PHE A CD1 1 ATOM 2521 C CD2 . PHE A 1 328 ? 5.178 -14.691 -6.669 1.00 25.46 ? 328 PHE A CD2 1 ATOM 2522 C CE1 . PHE A 1 328 ? 3.445 -15.231 -8.750 1.00 27.04 ? 328 PHE A CE1 1 ATOM 2523 C CE2 . PHE A 1 328 ? 4.605 -13.644 -7.389 1.00 22.31 ? 328 PHE A CE2 1 ATOM 2524 C CZ . PHE A 1 328 ? 3.742 -13.914 -8.425 1.00 28.16 ? 328 PHE A CZ 1 ATOM 2525 N N . ILE A 1 329 ? 2.340 -18.395 -5.577 1.00 22.41 ? 329 ILE A N 1 ATOM 2526 C CA . ILE A 1 329 ? 1.260 -19.230 -6.107 1.00 28.74 ? 329 ILE A CA 1 ATOM 2527 C C . ILE A 1 329 ? 0.817 -18.687 -7.457 1.00 29.64 ? 329 ILE A C 1 ATOM 2528 O O . ILE A 1 329 ? 0.531 -17.491 -7.598 1.00 28.37 ? 329 ILE A O 1 ATOM 2529 C CB . ILE A 1 329 ? 0.066 -19.268 -5.144 1.00 26.54 ? 329 ILE A CB 1 ATOM 2530 C CG1 . ILE A 1 329 ? 0.449 -19.897 -3.812 1.00 25.32 ? 329 ILE A CG1 1 ATOM 2531 C CG2 . ILE A 1 329 ? -1.107 -20.002 -5.796 1.00 26.59 ? 329 ILE A CG2 1 ATOM 2532 C CD1 . ILE A 1 329 ? -0.471 -19.477 -2.700 1.00 26.50 ? 329 ILE A CD1 1 ATOM 2533 N N . ALA A 1 330 ? 0.717 -19.566 -8.446 1.00 28.94 ? 330 ALA A N 1 ATOM 2534 C CA . ALA A 1 330 ? 0.191 -19.178 -9.742 1.00 34.41 ? 330 ALA A CA 1 ATOM 2535 C C . ALA A 1 330 ? -0.545 -20.369 -10.332 1.00 35.52 ? 330 ALA A C 1 ATOM 2536 O O . ALA A 1 330 ? -0.451 -21.488 -9.824 1.00 31.43 ? 330 ALA A O 1 ATOM 2537 C CB . ALA A 1 330 ? 1.305 -18.695 -10.676 1.00 34.52 ? 330 ALA A CB 1 ATOM 2538 N N . GLU A 1 331 ? -1.298 -20.118 -11.407 1.00 32.46 ? 331 GLU A N 1 ATOM 2539 C CA . GLU A 1 331 ? -1.903 -21.226 -12.144 1.00 40.74 ? 331 GLU A CA 1 ATOM 2540 C C . GLU A 1 331 ? -0.830 -22.185 -12.649 1.00 34.72 ? 331 GLU A C 1 ATOM 2541 O O . GLU A 1 331 ? -0.941 -23.407 -12.490 1.00 41.50 ? 331 GLU A O 1 ATOM 2542 C CB . GLU A 1 331 ? -2.746 -20.692 -13.302 1.00 51.05 ? 331 GLU A CB 1 ATOM 2543 C CG . GLU A 1 331 ? -4.014 -19.959 -12.875 1.00 57.34 ? 331 GLU A CG 1 ATOM 2544 C CD . GLU A 1 331 ? -3.779 -18.500 -12.489 1.00 65.00 ? 331 GLU A CD 1 ATOM 2545 O OE1 . GLU A 1 331 ? -2.607 -18.053 -12.439 1.00 58.37 ? 331 GLU A OE1 1 ATOM 2546 O OE2 . GLU A 1 331 ? -4.785 -17.796 -12.238 1.00 62.83 ? 331 GLU A OE2 1 ATOM 2547 N N . SER A 1 332 ? 0.232 -21.642 -13.234 1.00 36.45 ? 332 SER A N 1 ATOM 2548 C CA . SER A 1 332 ? 1.335 -22.431 -13.759 1.00 44.53 ? 332 SER A CA 1 ATOM 2549 C C . SER A 1 332 ? 2.543 -21.520 -13.923 1.00 42.61 ? 332 SER A C 1 ATOM 2550 O O . SER A 1 332 ? 2.413 -20.295 -13.971 1.00 40.34 ? 332 SER A O 1 ATOM 2551 C CB . SER A 1 332 ? 0.966 -23.075 -15.095 1.00 38.48 ? 332 SER A CB 1 ATOM 2552 O OG . SER A 1 332 ? 0.561 -22.076 -16.008 1.00 46.85 ? 332 SER A OG 1 ATOM 2553 N N . ARG A 1 333 ? 3.721 -22.140 -14.022 1.00 41.51 ? 333 ARG A N 1 ATOM 2554 C CA . ARG A 1 333 ? 4.946 -21.383 -14.259 1.00 41.73 ? 333 ARG A CA 1 ATOM 2555 C C . ARG A 1 333 ? 4.820 -20.505 -15.500 1.00 49.16 ? 333 ARG A C 1 ATOM 2556 O O . ARG A 1 333 ? 5.169 -19.318 -15.478 1.00 44.90 ? 333 ARG A O 1 ATOM 2557 C CB . ARG A 1 333 ? 6.134 -22.337 -14.392 1.00 44.08 ? 333 ARG A CB 1 ATOM 2558 C CG . ARG A 1 333 ? 6.690 -22.841 -13.072 1.00 44.61 ? 333 ARG A CG 1 ATOM 2559 C CD . ARG A 1 333 ? 7.603 -24.032 -13.301 1.00 48.48 ? 333 ARG A CD 1 ATOM 2560 N NE . ARG A 1 333 ? 8.524 -24.258 -12.193 1.00 48.28 ? 333 ARG A NE 1 ATOM 2561 C CZ . ARG A 1 333 ? 8.185 -24.797 -11.025 1.00 51.16 ? 333 ARG A CZ 1 ATOM 2562 N NH1 . ARG A 1 333 ? 6.931 -25.162 -10.792 1.00 52.43 ? 333 ARG A NH1 1 ATOM 2563 N NH2 . ARG A 1 333 ? 9.104 -24.965 -10.082 1.00 52.03 ? 333 ARG A NH2 1 ATOM 2564 N N . GLU A 1 334 ? 4.303 -21.066 -16.592 1.00 44.77 ? 334 GLU A N 1 ATOM 2565 C CA . GLU A 1 334 ? 4.161 -20.285 -17.815 1.00 48.41 ? 334 GLU A CA 1 ATOM 2566 C C . GLU A 1 334 ? 3.240 -19.085 -17.631 1.00 46.19 ? 334 GLU A C 1 ATOM 2567 O O . GLU A 1 334 ? 3.287 -18.148 -18.435 1.00 44.89 ? 334 GLU A O 1 ATOM 2568 C CB . GLU A 1 334 ? 3.648 -21.174 -18.953 1.00 56.62 ? 334 GLU A CB 1 ATOM 2569 C CG . GLU A 1 334 ? 4.668 -22.176 -19.490 1.00 54.05 ? 334 GLU A CG 1 ATOM 2570 C CD . GLU A 1 334 ? 4.921 -23.337 -18.541 1.00 62.56 ? 334 GLU A CD 1 ATOM 2571 O OE1 . GLU A 1 334 ? 4.075 -23.586 -17.653 1.00 59.40 ? 334 GLU A OE1 1 ATOM 2572 O OE2 . GLU A 1 334 ? 5.973 -24.000 -18.681 1.00 68.88 ? 334 GLU A OE2 1 ATOM 2573 N N . MET A 1 335 ? 2.414 -19.081 -16.587 1.00 45.97 ? 335 MET A N 1 ATOM 2574 C CA . MET A 1 335 ? 1.494 -17.984 -16.331 1.00 41.32 ? 335 MET A CA 1 ATOM 2575 C C . MET A 1 335 ? 1.999 -17.032 -15.248 1.00 42.34 ? 335 MET A C 1 ATOM 2576 O O . MET A 1 335 ? 1.214 -16.243 -14.713 1.00 37.36 ? 335 MET A O 1 ATOM 2577 C CB . MET A 1 335 ? 0.116 -18.534 -15.966 1.00 42.92 ? 335 MET A CB 1 ATOM 2578 C CG . MET A 1 335 ? -0.546 -19.281 -17.118 1.00 54.30 ? 335 MET A CG 1 ATOM 2579 S SD . MET A 1 335 ? -2.199 -19.875 -16.732 1.00 77.82 ? 335 MET A SD 1 ATOM 2580 C CE . MET A 1 335 ? -3.033 -18.334 -16.350 1.00 63.35 ? 335 MET A CE 1 ATOM 2581 N N . LEU A 1 336 ? 3.290 -17.087 -14.921 1.00 39.65 ? 336 LEU A N 1 ATOM 2582 C CA . LEU A 1 336 ? 3.854 -16.148 -13.962 1.00 31.66 ? 336 LEU A CA 1 ATOM 2583 C C . LEU A 1 336 ? 3.861 -14.732 -14.538 1.00 34.04 ? 336 LEU A C 1 ATOM 2584 O O . LEU A 1 336 ? 3.916 -14.549 -15.754 1.00 37.09 ? 336 LEU A O 1 ATOM 2585 C CB . LEU A 1 336 ? 5.269 -16.565 -13.591 1.00 30.57 ? 336 LEU A CB 1 ATOM 2586 C CG . LEU A 1 336 ? 5.280 -17.817 -12.714 1.00 31.13 ? 336 LEU A CG 1 ATOM 2587 C CD1 . LEU A 1 336 ? 6.688 -18.311 -12.499 1.00 33.26 ? 336 LEU A CD1 1 ATOM 2588 C CD2 . LEU A 1 336 ? 4.600 -17.543 -11.374 1.00 34.01 ? 336 LEU A CD2 1 ATOM 2589 N N . PRO A 1 337 ? 3.789 -13.645 -13.631 1.00 38.60 ? 337 PRO A N 1 ATOM 2590 C CA . PRO A 1 337 ? 3.820 -12.256 -14.140 1.00 33.87 ? 337 PRO A CA 1 ATOM 2591 C C . PRO A 1 337 ? 5.222 -11.812 -14.551 1.00 33.25 ? 337 PRO A C 1 ATOM 2592 O O . PRO A 1 337 ? 5.888 -11.006 -13.888 1.00 29.93 ? 337 PRO A O 1 ATOM 2593 C CB . PRO A 1 337 ? 3.277 -11.464 -12.947 1.00 35.01 ? 337 PRO A CB 1 ATOM 2594 C CG . PRO A 1 337 ? 3.806 -12.220 -11.767 1.00 32.44 ? 337 PRO A CG 1 ATOM 2595 C CD . PRO A 1 337 ? 3.660 -13.686 -12.161 1.00 33.61 ? 337 PRO A CD 1 ATOM 2596 N N . PHE A 1 338 ? 5.699 -12.342 -15.678 1.00 32.41 ? 338 PHE A N 1 ATOM 2597 C CA . PHE A 1 338 ? 6.995 -11.941 -16.206 1.00 31.40 ? 338 PHE A CA 1 ATOM 2598 C C . PHE A 1 338 ? 6.966 -10.467 -16.585 1.00 33.77 ? 338 PHE A C 1 ATOM 2599 O O . PHE A 1 338 ? 5.925 -9.928 -16.957 1.00 33.57 ? 338 PHE A O 1 ATOM 2600 C CB . PHE A 1 338 ? 7.369 -12.795 -17.426 1.00 32.87 ? 338 PHE A CB 1 ATOM 2601 C CG . PHE A 1 338 ? 7.492 -14.264 -17.123 1.00 33.80 ? 338 PHE A CG 1 ATOM 2602 C CD1 . PHE A 1 338 ? 8.656 -14.776 -16.575 1.00 35.83 ? 338 PHE A CD1 1 ATOM 2603 C CD2 . PHE A 1 338 ? 6.444 -15.132 -17.382 1.00 39.94 ? 338 PHE A CD2 1 ATOM 2604 C CE1 . PHE A 1 338 ? 8.773 -16.132 -16.284 1.00 36.89 ? 338 PHE A CE1 1 ATOM 2605 C CE2 . PHE A 1 338 ? 6.551 -16.486 -17.090 1.00 34.13 ? 338 PHE A CE2 1 ATOM 2606 C CZ . PHE A 1 338 ? 7.715 -16.987 -16.543 1.00 38.10 ? 338 PHE A CZ 1 ATOM 2607 N N . TRP A 1 339 ? 8.116 -9.805 -16.469 1.00 34.28 ? 339 TRP A N 1 ATOM 2608 C CA . TRP A 1 339 ? 8.189 -8.381 -16.759 1.00 36.17 ? 339 TRP A CA 1 ATOM 2609 C C . TRP A 1 339 ? 9.050 -8.112 -17.986 1.00 37.49 ? 339 TRP A C 1 ATOM 2610 O O . TRP A 1 339 ? 9.870 -8.934 -18.403 1.00 38.82 ? 339 TRP A O 1 ATOM 2611 C CB . TRP A 1 339 ? 8.696 -7.575 -15.548 1.00 31.82 ? 339 TRP A CB 1 ATOM 2612 C CG . TRP A 1 339 ? 10.109 -7.833 -15.077 1.00 28.82 ? 339 TRP A CG 1 ATOM 2613 C CD1 . TRP A 1 339 ? 10.540 -8.865 -14.291 1.00 29.04 ? 339 TRP A CD1 1 ATOM 2614 C CD2 . TRP A 1 339 ? 11.257 -7.006 -15.313 1.00 31.56 ? 339 TRP A CD2 1 ATOM 2615 N NE1 . TRP A 1 339 ? 11.884 -8.742 -14.043 1.00 30.01 ? 339 TRP A NE1 1 ATOM 2616 C CE2 . TRP A 1 339 ? 12.350 -7.612 -14.663 1.00 30.89 ? 339 TRP A CE2 1 ATOM 2617 C CE3 . TRP A 1 339 ? 11.467 -5.814 -16.020 1.00 32.18 ? 339 TRP A CE3 1 ATOM 2618 C CZ2 . TRP A 1 339 ? 13.640 -7.070 -14.697 1.00 35.86 ? 339 TRP A CZ2 1 ATOM 2619 C CZ3 . TRP A 1 339 ? 12.748 -5.275 -16.049 1.00 33.99 ? 339 TRP A CZ3 1 ATOM 2620 C CH2 . TRP A 1 339 ? 13.814 -5.902 -15.394 1.00 31.88 ? 339 TRP A CH2 1 ATOM 2621 N N . MET A 1 340 ? 8.837 -6.935 -18.568 1.00 37.88 ? 340 MET A N 1 ATOM 2622 C CA . MET A 1 340 ? 9.413 -6.589 -19.864 1.00 44.06 ? 340 MET A CA 1 ATOM 2623 C C . MET A 1 340 ? 10.804 -6.010 -19.645 1.00 43.10 ? 340 MET A C 1 ATOM 2624 O O . MET A 1 340 ? 10.995 -4.795 -19.578 1.00 43.89 ? 340 MET A O 1 ATOM 2625 C CB . MET A 1 340 ? 8.507 -5.616 -20.605 1.00 45.38 ? 340 MET A CB 1 ATOM 2626 C CG . MET A 1 340 ? 8.977 -5.312 -22.007 1.00 52.22 ? 340 MET A CG 1 ATOM 2627 S SD . MET A 1 340 ? 8.019 -4.004 -22.777 1.00 64.04 ? 340 MET A SD 1 ATOM 2628 C CE . MET A 1 340 ? 6.403 -4.774 -22.847 1.00 61.92 ? 340 MET A CE 1 ATOM 2629 N N . ASN A 1 341 ? 11.788 -6.897 -19.532 1.00 41.78 ? 341 ASN A N 1 ATOM 2630 C CA . ASN A 1 341 ? 13.184 -6.510 -19.421 1.00 43.04 ? 341 ASN A CA 1 ATOM 2631 C C . ASN A 1 341 ? 13.866 -6.375 -20.776 1.00 53.46 ? 341 ASN A C 1 ATOM 2632 O O . ASN A 1 341 ? 15.077 -6.126 -20.821 1.00 48.65 ? 341 ASN A O 1 ATOM 2633 C CB . ASN A 1 341 ? 13.945 -7.531 -18.576 1.00 48.31 ? 341 ASN A CB 1 ATOM 2634 C CG . ASN A 1 341 ? 14.078 -8.867 -19.274 1.00 43.27 ? 341 ASN A CG 1 ATOM 2635 O OD1 . ASN A 1 341 ? 13.174 -9.302 -19.981 1.00 51.28 ? 341 ASN A OD1 1 ATOM 2636 N ND2 . ASN A 1 341 ? 15.210 -9.517 -19.081 1.00 50.88 ? 341 ASN A ND2 1 ATOM 2637 N N . SER A 1 342 ? 13.123 -6.538 -21.869 1.00 55.50 ? 342 SER A N 1 ATOM 2638 C CA . SER A 1 342 ? 13.685 -6.518 -23.214 1.00 59.70 ? 342 SER A CA 1 ATOM 2639 C C . SER A 1 342 ? 12.592 -6.092 -24.186 1.00 61.75 ? 342 SER A C 1 ATOM 2640 O O . SER A 1 342 ? 11.447 -5.850 -23.797 1.00 64.99 ? 342 SER A O 1 ATOM 2641 C CB . SER A 1 342 ? 14.268 -7.883 -23.591 1.00 60.33 ? 342 SER A CB 1 ATOM 2642 O OG . SER A 1 342 ? 13.264 -8.885 -23.581 1.00 64.46 ? 342 SER A OG 1 ATOM 2643 N N . THR A 1 343 ? 12.952 -6.036 -25.470 1.00 71.03 ? 343 THR A N 1 ATOM 2644 C CA . THR A 1 343 ? 12.074 -5.435 -26.472 1.00 71.71 ? 343 THR A CA 1 ATOM 2645 C C . THR A 1 343 ? 10.791 -6.240 -26.662 1.00 70.74 ? 343 THR A C 1 ATOM 2646 O O . THR A 1 343 ? 9.685 -5.696 -26.567 1.00 72.47 ? 343 THR A O 1 ATOM 2647 C CB . THR A 1 343 ? 12.821 -5.299 -27.801 1.00 76.08 ? 343 THR A CB 1 ATOM 2648 O OG1 . THR A 1 343 ? 13.338 -6.579 -28.192 1.00 75.81 ? 343 THR A OG1 1 ATOM 2649 C CG2 . THR A 1 343 ? 13.971 -4.307 -27.669 1.00 70.67 ? 343 THR A CG2 1 ATOM 2650 N N . GLY A 1 344 ? 10.918 -7.537 -26.939 1.00 72.41 ? 344 GLY A N 1 ATOM 2651 C CA . GLY A 1 344 ? 9.774 -8.338 -27.336 1.00 72.58 ? 344 GLY A CA 1 ATOM 2652 C C . GLY A 1 344 ? 8.919 -8.873 -26.204 1.00 71.80 ? 344 GLY A C 1 ATOM 2653 O O . GLY A 1 344 ? 8.423 -8.106 -25.373 1.00 73.04 ? 344 GLY A O 1 ATOM 2654 N N . LYS A 1 345 ? 8.738 -10.192 -26.172 1.00 72.69 ? 345 LYS A N 1 ATOM 2655 C CA . LYS A 1 345 ? 7.869 -10.814 -25.181 1.00 66.33 ? 345 LYS A CA 1 ATOM 2656 C C . LYS A 1 345 ? 8.427 -10.624 -23.773 1.00 64.52 ? 345 LYS A C 1 ATOM 2657 O O . LYS A 1 345 ? 9.642 -10.563 -23.562 1.00 65.09 ? 345 LYS A O 1 ATOM 2658 C CB . LYS A 1 345 ? 7.703 -12.304 -25.486 1.00 58.20 ? 345 LYS A CB 1 ATOM 2659 N N . ARG A 1 346 ? 7.519 -10.527 -22.801 1.00 58.18 ? 346 ARG A N 1 ATOM 2660 C CA . ARG A 1 346 ? 7.907 -10.353 -21.404 1.00 49.02 ? 346 ARG A CA 1 ATOM 2661 C C . ARG A 1 346 ? 8.507 -11.649 -20.877 1.00 43.92 ? 346 ARG A C 1 ATOM 2662 O O . ARG A 1 346 ? 7.808 -12.654 -20.734 1.00 46.58 ? 346 ARG A O 1 ATOM 2663 C CB . ARG A 1 346 ? 6.706 -9.924 -20.569 1.00 49.04 ? 346 ARG A CB 1 ATOM 2664 C CG . ARG A 1 346 ? 6.231 -8.519 -20.887 1.00 51.06 ? 346 ARG A CG 1 ATOM 2665 C CD . ARG A 1 346 ? 5.062 -8.101 -20.016 1.00 47.34 ? 346 ARG A CD 1 ATOM 2666 N NE . ARG A 1 346 ? 4.033 -9.133 -19.944 1.00 63.64 ? 346 ARG A NE 1 ATOM 2667 C CZ . ARG A 1 346 ? 3.212 -9.457 -20.941 1.00 73.28 ? 346 ARG A CZ 1 ATOM 2668 N NH1 . ARG A 1 346 ? 2.307 -10.412 -20.766 1.00 73.24 ? 346 ARG A NH1 1 ATOM 2669 N NH2 . ARG A 1 346 ? 3.299 -8.841 -22.114 1.00 72.93 ? 346 ARG A NH2 1 ATOM 2670 N N . GLU A 1 347 ? 9.804 -11.624 -20.589 1.00 44.03 ? 347 GLU A N 1 ATOM 2671 C CA . GLU A 1 347 ? 10.525 -12.795 -20.125 1.00 42.62 ? 347 GLU A CA 1 ATOM 2672 C C . GLU A 1 347 ? 11.253 -12.567 -18.809 1.00 39.82 ? 347 GLU A C 1 ATOM 2673 O O . GLU A 1 347 ? 11.932 -13.483 -18.330 1.00 39.49 ? 347 GLU A O 1 ATOM 2674 C CB . GLU A 1 347 ? 11.541 -13.242 -21.190 1.00 49.44 ? 347 GLU A CB 1 ATOM 2675 C CG . GLU A 1 347 ? 12.651 -12.226 -21.427 1.00 55.28 ? 347 GLU A CG 1 ATOM 2676 C CD . GLU A 1 347 ? 13.367 -12.427 -22.754 1.00 66.08 ? 347 GLU A CD 1 ATOM 2677 O OE1 . GLU A 1 347 ? 12.758 -13.007 -23.677 1.00 71.80 ? 347 GLU A OE1 1 ATOM 2678 O OE2 . GLU A 1 347 ? 14.538 -12.005 -22.877 1.00 65.43 ? 347 GLU A OE2 1 ATOM 2679 N N . GLY A 1 348 ? 11.151 -11.377 -18.219 1.00 37.28 ? 348 GLY A N 1 ATOM 2680 C CA . GLY A 1 348 ? 11.898 -11.083 -17.005 1.00 37.10 ? 348 GLY A CA 1 ATOM 2681 C C . GLY A 1 348 ? 11.312 -11.787 -15.790 1.00 34.22 ? 348 GLY A C 1 ATOM 2682 O O . GLY A 1 348 ? 10.095 -11.774 -15.578 1.00 33.21 ? 348 GLY A O 1 ATOM 2683 N N . TRP A 1 349 ? 12.181 -12.409 -14.994 1.00 29.67 ? 349 TRP A N 1 ATOM 2684 C CA . TRP A 1 349 ? 11.769 -12.997 -13.729 1.00 29.76 ? 349 TRP A CA 1 ATOM 2685 C C . TRP A 1 349 ? 11.652 -11.912 -12.663 1.00 31.86 ? 349 TRP A C 1 ATOM 2686 O O . TRP A 1 349 ? 12.470 -10.992 -12.609 1.00 29.99 ? 349 TRP A O 1 ATOM 2687 C CB . TRP A 1 349 ? 12.775 -14.045 -13.254 1.00 33.96 ? 349 TRP A CB 1 ATOM 2688 C CG . TRP A 1 349 ? 12.814 -15.305 -14.054 1.00 35.70 ? 349 TRP A CG 1 ATOM 2689 C CD1 . TRP A 1 349 ? 12.292 -15.515 -15.303 1.00 40.57 ? 349 TRP A CD1 1 ATOM 2690 C CD2 . TRP A 1 349 ? 13.405 -16.544 -13.650 1.00 40.31 ? 349 TRP A CD2 1 ATOM 2691 N NE1 . TRP A 1 349 ? 12.530 -16.818 -15.698 1.00 35.56 ? 349 TRP A NE1 1 ATOM 2692 C CE2 . TRP A 1 349 ? 13.208 -17.466 -14.698 1.00 40.92 ? 349 TRP A CE2 1 ATOM 2693 C CE3 . TRP A 1 349 ? 14.080 -16.964 -12.499 1.00 42.07 ? 349 TRP A CE3 1 ATOM 2694 C CZ2 . TRP A 1 349 ? 13.666 -18.781 -14.626 1.00 38.28 ? 349 TRP A CZ2 1 ATOM 2695 C CZ3 . TRP A 1 349 ? 14.534 -18.272 -12.432 1.00 43.68 ? 349 TRP A CZ3 1 ATOM 2696 C CH2 . TRP A 1 349 ? 14.323 -19.161 -13.487 1.00 39.30 ? 349 TRP A CH2 1 ATOM 2697 N N . GLN A 1 350 ? 10.640 -12.034 -11.809 1.00 25.97 ? 350 GLN A N 1 ATOM 2698 C CA . GLN A 1 350 ? 10.532 -11.157 -10.651 1.00 28.21 ? 350 GLN A CA 1 ATOM 2699 C C . GLN A 1 350 ? 11.404 -11.701 -9.529 1.00 27.89 ? 350 GLN A C 1 ATOM 2700 O O . GLN A 1 350 ? 11.515 -12.920 -9.340 1.00 27.26 ? 350 GLN A O 1 ATOM 2701 C CB . GLN A 1 350 ? 9.079 -11.045 -10.188 1.00 27.07 ? 350 GLN A CB 1 ATOM 2702 C CG . GLN A 1 350 ? 8.098 -10.626 -11.276 1.00 27.44 ? 350 GLN A CG 1 ATOM 2703 C CD . GLN A 1 350 ? 8.033 -9.124 -11.475 1.00 27.37 ? 350 GLN A CD 1 ATOM 2704 O OE1 . GLN A 1 350 ? 8.760 -8.361 -10.831 1.00 27.21 ? 350 GLN A OE1 1 ATOM 2705 N NE2 . GLN A 1 350 ? 7.152 -8.690 -12.373 1.00 25.98 ? 350 GLN A NE2 1 ATOM 2706 N N . ARG A 1 351 ? 12.051 -10.793 -8.801 1.00 25.81 ? 351 ARG A N 1 ATOM 2707 C CA . ARG A 1 351 ? 12.987 -11.176 -7.758 1.00 22.04 ? 351 ARG A CA 1 ATOM 2708 C C . ARG A 1 351 ? 12.564 -10.719 -6.372 1.00 23.64 ? 351 ARG A C 1 ATOM 2709 O O . ARG A 1 351 ? 13.167 -11.151 -5.381 1.00 23.02 ? 351 ARG A O 1 ATOM 2710 C CB . ARG A 1 351 ? 14.383 -10.620 -8.076 1.00 28.79 ? 351 ARG A CB 1 ATOM 2711 C CG . ARG A 1 351 ? 14.938 -11.107 -9.400 1.00 33.09 ? 351 ARG A CG 1 ATOM 2712 C CD . ARG A 1 351 ? 15.011 -12.611 -9.418 1.00 38.35 ? 351 ARG A CD 1 ATOM 2713 N NE . ARG A 1 351 ? 16.325 -13.096 -9.836 1.00 52.66 ? 351 ARG A NE 1 ATOM 2714 C CZ . ARG A 1 351 ? 16.679 -14.378 -9.833 1.00 57.57 ? 351 ARG A CZ 1 ATOM 2715 N NH1 . ARG A 1 351 ? 15.815 -15.309 -9.438 1.00 52.65 ? 351 ARG A NH1 1 ATOM 2716 N NH2 . ARG A 1 351 ? 17.893 -14.730 -10.230 1.00 58.32 ? 351 ARG A NH2 1 ATOM 2717 N N . GLY A 1 352 ? 11.576 -9.836 -6.278 1.00 20.89 ? 352 GLY A N 1 ATOM 2718 C CA . GLY A 1 352 ? 11.034 -9.443 -5.001 1.00 22.23 ? 352 GLY A CA 1 ATOM 2719 C C . GLY A 1 352 ? 9.520 -9.382 -5.075 1.00 17.59 ? 352 GLY A C 1 ATOM 2720 O O . GLY A 1 352 ? 8.939 -9.143 -6.139 1.00 21.50 ? 352 GLY A O 1 ATOM 2721 N N . TRP A 1 353 ? 8.887 -9.585 -3.923 1.00 19.73 ? 353 TRP A N 1 ATOM 2722 C CA . TRP A 1 353 ? 7.425 -9.526 -3.873 1.00 16.58 ? 353 TRP A CA 1 ATOM 2723 C C . TRP A 1 353 ? 6.972 -9.266 -2.439 1.00 19.69 ? 353 TRP A C 1 ATOM 2724 O O . TRP A 1 353 ? 7.780 -9.209 -1.511 1.00 20.64 ? 353 TRP A O 1 ATOM 2725 C CB . TRP A 1 353 ? 6.805 -10.811 -4.435 1.00 19.95 ? 353 TRP A CB 1 ATOM 2726 C CG . TRP A 1 353 ? 5.478 -10.620 -5.120 1.00 19.41 ? 353 TRP A CG 1 ATOM 2727 C CD1 . TRP A 1 353 ? 4.240 -10.774 -4.565 1.00 18.47 ? 353 TRP A CD1 1 ATOM 2728 C CD2 . TRP A 1 353 ? 5.263 -10.271 -6.495 1.00 21.34 ? 353 TRP A CD2 1 ATOM 2729 N NE1 . TRP A 1 353 ? 3.264 -10.533 -5.512 1.00 21.96 ? 353 TRP A NE1 1 ATOM 2730 C CE2 . TRP A 1 353 ? 3.870 -10.225 -6.703 1.00 20.66 ? 353 TRP A CE2 1 ATOM 2731 C CE3 . TRP A 1 353 ? 6.116 -9.990 -7.568 1.00 20.01 ? 353 TRP A CE3 1 ATOM 2732 C CZ2 . TRP A 1 353 ? 3.308 -9.901 -7.936 1.00 25.24 ? 353 TRP A CZ2 1 ATOM 2733 C CZ3 . TRP A 1 353 ? 5.552 -9.660 -8.795 1.00 27.34 ? 353 TRP A CZ3 1 ATOM 2734 C CH2 . TRP A 1 353 ? 4.164 -9.620 -8.967 1.00 26.22 ? 353 TRP A CH2 1 ATOM 2735 N N . HIS A 1 354 ? 5.659 -9.064 -2.275 1.00 18.06 ? 354 HIS A N 1 ATOM 2736 C CA . HIS A 1 354 ? 5.071 -8.757 -0.976 1.00 18.47 ? 354 HIS A CA 1 ATOM 2737 C C . HIS A 1 354 ? 3.612 -9.192 -0.994 1.00 18.09 ? 354 HIS A C 1 ATOM 2738 O O . HIS A 1 354 ? 3.052 -9.501 -2.046 1.00 25.98 ? 354 HIS A O 1 ATOM 2739 C CB . HIS A 1 354 ? 5.165 -7.256 -0.662 1.00 19.20 ? 354 HIS A CB 1 ATOM 2740 C CG . HIS A 1 354 ? 4.590 -6.407 -1.745 1.00 20.02 ? 354 HIS A CG 1 ATOM 2741 N ND1 . HIS A 1 354 ? 3.249 -6.088 -1.808 1.00 18.22 ? 354 HIS A ND1 1 ATOM 2742 C CD2 . HIS A 1 354 ? 5.156 -5.885 -2.858 1.00 19.81 ? 354 HIS A CD2 1 ATOM 2743 C CE1 . HIS A 1 354 ? 3.022 -5.387 -2.901 1.00 17.82 ? 354 HIS A CE1 1 ATOM 2744 N NE2 . HIS A 1 354 ? 4.161 -5.243 -3.550 1.00 21.31 ? 354 HIS A NE2 1 ATOM 2745 N N . GLY A 1 355 ? 2.975 -9.148 0.173 1.00 18.11 ? 355 GLY A N 1 ATOM 2746 C CA . GLY A 1 355 ? 1.601 -9.608 0.283 1.00 17.25 ? 355 GLY A CA 1 ATOM 2747 C C . GLY A 1 355 ? 1.420 -10.612 1.403 1.00 20.30 ? 355 GLY A C 1 ATOM 2748 O O . GLY A 1 355 ? 0.314 -10.823 1.908 1.00 20.89 ? 355 GLY A O 1 ATOM 2749 N N . TYR A 1 356 ? 2.536 -11.210 1.816 1.00 21.99 ? 356 TYR A N 1 ATOM 2750 C CA . TYR A 1 356 ? 2.574 -12.230 2.855 1.00 19.26 ? 356 TYR A CA 1 ATOM 2751 C C . TYR A 1 356 ? 2.076 -11.695 4.199 1.00 22.45 ? 356 TYR A C 1 ATOM 2752 O O . TYR A 1 356 ? 1.852 -10.497 4.383 1.00 21.98 ? 356 TYR A O 1 ATOM 2753 C CB . TYR A 1 356 ? 4.006 -12.721 3.044 1.00 18.69 ? 356 TYR A CB 1 ATOM 2754 C CG . TYR A 1 356 ? 4.655 -13.173 1.765 1.00 21.03 ? 356 TYR A CG 1 ATOM 2755 C CD1 . TYR A 1 356 ? 4.405 -14.444 1.261 1.00 19.42 ? 356 TYR A CD1 1 ATOM 2756 C CD2 . TYR A 1 356 ? 5.515 -12.342 1.067 1.00 20.07 ? 356 TYR A CD2 1 ATOM 2757 C CE1 . TYR A 1 356 ? 4.993 -14.867 0.086 1.00 18.74 ? 356 TYR A CE1 1 ATOM 2758 C CE2 . TYR A 1 356 ? 6.106 -12.751 -0.124 1.00 22.18 ? 356 TYR A CE2 1 ATOM 2759 C CZ . TYR A 1 356 ? 5.839 -14.023 -0.600 1.00 22.08 ? 356 TYR A CZ 1 ATOM 2760 O OH . TYR A 1 356 ? 6.422 -14.445 -1.766 1.00 22.04 ? 356 TYR A OH 1 ATOM 2761 N N . ASP A 1 357 ? 1.949 -12.626 5.150 1.00 18.97 ? 357 ASP A N 1 ATOM 2762 C CA . ASP A 1 357 ? 1.698 -12.384 6.569 1.00 18.67 ? 357 ASP A CA 1 ATOM 2763 C C . ASP A 1 357 ? 2.260 -11.034 6.999 1.00 20.78 ? 357 ASP A C 1 ATOM 2764 O O . ASP A 1 357 ? 3.455 -10.763 6.831 1.00 18.94 ? 357 ASP A O 1 ATOM 2765 C CB . ASP A 1 357 ? 2.326 -13.526 7.383 1.00 22.38 ? 357 ASP A CB 1 ATOM 2766 C CG . ASP A 1 357 ? 1.990 -13.474 8.871 1.00 29.17 ? 357 ASP A CG 1 ATOM 2767 O OD1 . ASP A 1 357 ? 1.704 -12.391 9.430 1.00 23.88 ? 357 ASP A OD1 1 ATOM 2768 O OD2 . ASP A 1 357 ? 2.054 -14.556 9.505 1.00 32.35 ? 357 ASP A OD2 1 ATOM 2769 N N . ASN A 1 358 ? 1.398 -10.169 7.526 1.00 18.89 ? 358 ASN A N 1 ATOM 2770 C CA . ASN A 1 358 ? 1.811 -8.778 7.711 1.00 17.08 ? 358 ASN A CA 1 ATOM 2771 C C . ASN A 1 358 ? 2.720 -8.585 8.911 1.00 23.60 ? 358 ASN A C 1 ATOM 2772 O O . ASN A 1 358 ? 3.186 -7.459 9.129 1.00 21.06 ? 358 ASN A O 1 ATOM 2773 C CB . ASN A 1 358 ? 0.577 -7.880 7.863 1.00 17.68 ? 358 ASN A CB 1 ATOM 2774 C CG . ASN A 1 358 ? -0.281 -8.272 9.070 1.00 23.57 ? 358 ASN A CG 1 ATOM 2775 O OD1 . ASN A 1 358 ? -0.524 -9.451 9.292 1.00 21.62 ? 358 ASN A OD1 1 ATOM 2776 N ND2 . ASN A 1 358 ? -0.717 -7.284 9.863 1.00 18.33 ? 358 ASN A ND2 1 ATOM 2777 N N . GLU A 1 359 ? 2.964 -9.639 9.699 1.00 21.62 ? 359 GLU A N 1 ATOM 2778 C CA . GLU A 1 359 ? 3.891 -9.578 10.823 1.00 22.28 ? 359 GLU A CA 1 ATOM 2779 C C . GLU A 1 359 ? 5.298 -10.039 10.462 1.00 25.07 ? 359 GLU A C 1 ATOM 2780 O O . GLU A 1 359 ? 6.178 -10.025 11.329 1.00 27.44 ? 359 GLU A O 1 ATOM 2781 C CB . GLU A 1 359 ? 3.362 -10.418 11.990 1.00 25.99 ? 359 GLU A CB 1 ATOM 2782 C CG . GLU A 1 359 ? 2.022 -9.930 12.537 1.00 26.74 ? 359 GLU A CG 1 ATOM 2783 C CD . GLU A 1 359 ? 2.110 -8.610 13.285 1.00 31.96 ? 359 GLU A CD 1 ATOM 2784 O OE1 . GLU A 1 359 ? 3.233 -8.178 13.619 1.00 28.88 ? 359 GLU A OE1 1 ATOM 2785 O OE2 . GLU A 1 359 ? 1.039 -8.000 13.537 1.00 35.57 ? 359 GLU A OE2 1 ATOM 2786 N N . LEU A 1 360 ? 5.531 -10.437 9.214 1.00 20.78 ? 360 LEU A N 1 ATOM 2787 C CA . LEU A 1 360 ? 6.876 -10.758 8.758 1.00 21.75 ? 360 LEU A CA 1 ATOM 2788 C C . LEU A 1 360 ? 7.754 -9.511 8.721 1.00 24.19 ? 360 LEU A C 1 ATOM 2789 O O . LEU A 1 360 ? 7.348 -8.450 8.226 1.00 20.24 ? 360 LEU A O 1 ATOM 2790 C CB . LEU A 1 360 ? 6.817 -11.409 7.377 1.00 18.24 ? 360 LEU A CB 1 ATOM 2791 C CG . LEU A 1 360 ? 6.223 -12.818 7.399 1.00 21.09 ? 360 LEU A CG 1 ATOM 2792 C CD1 . LEU A 1 360 ? 5.875 -13.296 6.023 1.00 19.99 ? 360 LEU A CD1 1 ATOM 2793 C CD2 . LEU A 1 360 ? 7.258 -13.764 8.005 1.00 25.27 ? 360 LEU A CD2 1 ATOM 2794 N N . MET A 1 361 ? 8.977 -9.648 9.255 1.00 20.63 ? 361 MET A N 1 ATOM 2795 C CA . MET A 1 361 ? 9.895 -8.513 9.314 1.00 22.49 ? 361 MET A CA 1 ATOM 2796 C C . MET A 1 361 ? 10.077 -7.847 7.951 1.00 19.79 ? 361 MET A C 1 ATOM 2797 O O . MET A 1 361 ? 10.122 -6.613 7.860 1.00 21.10 ? 361 MET A O 1 ATOM 2798 C CB . MET A 1 361 ? 11.251 -8.958 9.870 1.00 24.21 ? 361 MET A CB 1 ATOM 2799 C CG . MET A 1 361 ? 12.206 -7.796 10.060 1.00 30.41 ? 361 MET A CG 1 ATOM 2800 S SD . MET A 1 361 ? 13.849 -8.379 10.523 1.00 32.86 ? 361 MET A SD 1 ATOM 2801 C CE . MET A 1 361 ? 14.038 -9.749 9.396 1.00 36.91 ? 361 MET A CE 1 ATOM 2802 N N . ASP A 1 362 ? 10.187 -8.632 6.877 1.00 20.23 ? 362 ASP A N 1 ATOM 2803 C CA . ASP A 1 362 ? 10.411 -8.010 5.569 1.00 17.22 ? 362 ASP A CA 1 ATOM 2804 C C . ASP A 1 362 ? 9.185 -7.253 5.047 1.00 19.54 ? 362 ASP A C 1 ATOM 2805 O O . ASP A 1 362 ? 9.324 -6.462 4.110 1.00 22.51 ? 362 ASP A O 1 ATOM 2806 C CB . ASP A 1 362 ? 10.831 -9.048 4.528 1.00 21.34 ? 362 ASP A CB 1 ATOM 2807 C CG . ASP A 1 362 ? 12.277 -9.537 4.706 1.00 24.75 ? 362 ASP A CG 1 ATOM 2808 O OD1 . ASP A 1 362 ? 13.006 -9.014 5.570 1.00 25.46 ? 362 ASP A OD1 1 ATOM 2809 O OD2 . ASP A 1 362 ? 12.692 -10.430 3.932 1.00 23.78 ? 362 ASP A OD2 1 ATOM 2810 N N . MET A 1 363 ? 7.997 -7.487 5.593 1.00 16.98 ? 363 MET A N 1 ATOM 2811 C CA . MET A 1 363 ? 6.810 -6.757 5.144 1.00 17.92 ? 363 MET A CA 1 ATOM 2812 C C . MET A 1 363 ? 6.651 -5.408 5.833 1.00 20.08 ? 363 MET A C 1 ATOM 2813 O O . MET A 1 363 ? 5.748 -4.633 5.470 1.00 20.42 ? 363 MET A O 1 ATOM 2814 C CB . MET A 1 363 ? 5.549 -7.604 5.353 1.00 18.49 ? 363 MET A CB 1 ATOM 2815 C CG . MET A 1 363 ? 5.483 -8.871 4.489 1.00 19.77 ? 363 MET A CG 1 ATOM 2816 S SD . MET A 1 363 ? 5.546 -8.617 2.708 1.00 20.19 ? 363 MET A SD 1 ATOM 2817 C CE . MET A 1 363 ? 7.290 -8.958 2.328 1.00 18.43 ? 363 MET A CE 1 ATOM 2818 N N . ARG A 1 364 ? 7.510 -5.105 6.804 1.00 19.17 ? 364 ARG A N 1 ATOM 2819 C CA . ARG A 1 364 ? 7.452 -3.825 7.499 1.00 20.07 ? 364 ARG A CA 1 ATOM 2820 C C . ARG A 1 364 ? 7.710 -2.662 6.550 1.00 18.75 ? 364 ARG A C 1 ATOM 2821 O O . ARG A 1 364 ? 8.602 -2.727 5.697 1.00 18.17 ? 364 ARG A O 1 ATOM 2822 C CB . ARG A 1 364 ? 8.497 -3.782 8.609 1.00 18.65 ? 364 ARG A CB 1 ATOM 2823 C CG . ARG A 1 364 ? 8.204 -4.686 9.791 1.00 21.11 ? 364 ARG A CG 1 ATOM 2824 C CD . ARG A 1 364 ? 9.474 -4.827 10.651 1.00 23.80 ? 364 ARG A CD 1 ATOM 2825 N NE . ARG A 1 364 ? 9.273 -5.804 11.711 1.00 25.90 ? 364 ARG A NE 1 ATOM 2826 C CZ . ARG A 1 364 ? 10.186 -6.134 12.623 1.00 29.25 ? 364 ARG A CZ 1 ATOM 2827 N NH1 . ARG A 1 364 ? 11.379 -5.558 12.625 1.00 27.07 ? 364 ARG A NH1 1 ATOM 2828 N NH2 . ARG A 1 364 ? 9.896 -7.054 13.536 1.00 30.56 ? 364 ARG A NH2 1 ATOM 2829 N N . GLY A 1 365 ? 6.957 -1.575 6.754 1.00 19.31 ? 365 GLY A N 1 ATOM 2830 C CA . GLY A 1 365 ? 7.141 -0.327 6.048 1.00 20.06 ? 365 GLY A CA 1 ATOM 2831 C C . GLY A 1 365 ? 7.716 0.756 6.948 1.00 19.89 ? 365 GLY A C 1 ATOM 2832 O O . GLY A 1 365 ? 8.326 0.480 7.983 1.00 18.91 ? 365 GLY A O 1 ATOM 2833 N N . ILE A 1 366 ? 7.532 2.017 6.529 1.00 17.07 ? 366 ILE A N 1 ATOM 2834 C CA . ILE A 1 366 ? 8.123 3.160 7.228 1.00 20.56 ? 366 ILE A CA 1 ATOM 2835 C C . ILE A 1 366 ? 7.070 4.209 7.589 1.00 21.96 ? 366 ILE A C 1 ATOM 2836 O O . ILE A 1 366 ? 6.006 4.298 6.978 1.00 19.54 ? 366 ILE A O 1 ATOM 2837 C CB . ILE A 1 366 ? 9.238 3.837 6.397 1.00 18.60 ? 366 ILE A CB 1 ATOM 2838 C CG1 . ILE A 1 366 ? 8.706 4.281 5.021 1.00 19.30 ? 366 ILE A CG1 1 ATOM 2839 C CG2 . ILE A 1 366 ? 10.462 2.910 6.251 1.00 16.87 ? 366 ILE A CG2 1 ATOM 2840 C CD1 . ILE A 1 366 ? 9.487 5.463 4.427 1.00 24.63 ? 366 ILE A CD1 1 ATOM 2841 N N . PHE A 1 367 ? 7.401 5.031 8.592 1.00 19.48 ? 367 PHE A N 1 ATOM 2842 C CA . PHE A 1 367 ? 6.667 6.264 8.873 1.00 20.41 ? 367 PHE A CA 1 ATOM 2843 C C . PHE A 1 367 ? 7.647 7.298 9.414 1.00 22.92 ? 367 PHE A C 1 ATOM 2844 O O . PHE A 1 367 ? 8.394 7.013 10.357 1.00 20.66 ? 367 PHE A O 1 ATOM 2845 C CB . PHE A 1 367 ? 5.529 6.059 9.886 1.00 19.81 ? 367 PHE A CB 1 ATOM 2846 C CG . PHE A 1 367 ? 4.802 7.346 10.273 1.00 23.01 ? 367 PHE A CG 1 ATOM 2847 C CD1 . PHE A 1 367 ? 5.327 8.209 11.237 1.00 25.92 ? 367 PHE A CD1 1 ATOM 2848 C CD2 . PHE A 1 367 ? 3.601 7.680 9.678 1.00 21.97 ? 367 PHE A CD2 1 ATOM 2849 C CE1 . PHE A 1 367 ? 4.670 9.376 11.581 1.00 23.66 ? 367 PHE A CE1 1 ATOM 2850 C CE2 . PHE A 1 367 ? 2.919 8.859 10.016 1.00 24.09 ? 367 PHE A CE2 1 ATOM 2851 C CZ . PHE A 1 367 ? 3.449 9.706 10.970 1.00 28.40 ? 367 PHE A CZ 1 ATOM 2852 N N . LEU A 1 368 ? 7.623 8.497 8.829 1.00 18.54 ? 368 LEU A N 1 ATOM 2853 C CA . LEU A 1 368 ? 8.399 9.623 9.335 1.00 21.61 ? 368 LEU A CA 1 ATOM 2854 C C . LEU A 1 368 ? 7.548 10.879 9.268 1.00 24.27 ? 368 LEU A C 1 ATOM 2855 O O . LEU A 1 368 ? 6.575 10.965 8.507 1.00 22.54 ? 368 LEU A O 1 ATOM 2856 C CB . LEU A 1 368 ? 9.694 9.854 8.550 1.00 20.21 ? 368 LEU A CB 1 ATOM 2857 C CG . LEU A 1 368 ? 10.674 8.684 8.497 1.00 24.98 ? 368 LEU A CG 1 ATOM 2858 C CD1 . LEU A 1 368 ? 10.381 7.887 7.257 1.00 24.61 ? 368 LEU A CD1 1 ATOM 2859 C CD2 . LEU A 1 368 ? 12.127 9.177 8.511 1.00 28.55 ? 368 LEU A CD2 1 ATOM 2860 N N . ALA A 1 369 ? 7.931 11.867 10.068 1.00 22.17 ? 369 ALA A N 1 ATOM 2861 C CA . ALA A 1 369 ? 7.200 13.123 10.067 1.00 18.97 ? 369 ALA A CA 1 ATOM 2862 C C . ALA A 1 369 ? 8.123 14.241 10.522 1.00 24.90 ? 369 ALA A C 1 ATOM 2863 O O . ALA A 1 369 ? 9.035 14.026 11.326 1.00 26.78 ? 369 ALA A O 1 ATOM 2864 C CB . ALA A 1 369 ? 5.970 13.052 10.968 1.00 23.35 ? 369 ALA A CB 1 ATOM 2865 N N . ILE A 1 370 ? 7.886 15.433 9.987 1.00 28.17 ? 370 ILE A N 1 ATOM 2866 C CA . ILE A 1 370 ? 8.720 16.588 10.294 1.00 27.93 ? 370 ILE A CA 1 ATOM 2867 C C . ILE A 1 370 ? 7.879 17.846 10.125 1.00 28.83 ? 370 ILE A C 1 ATOM 2868 O O . ILE A 1 370 ? 7.057 17.951 9.206 1.00 24.49 ? 370 ILE A O 1 ATOM 2869 C CB . ILE A 1 370 ? 9.991 16.614 9.413 1.00 25.87 ? 370 ILE A CB 1 ATOM 2870 C CG1 . ILE A 1 370 ? 10.912 17.768 9.838 1.00 26.41 ? 370 ILE A CG1 1 ATOM 2871 C CG2 . ILE A 1 370 ? 9.641 16.686 7.919 1.00 24.95 ? 370 ILE A CG2 1 ATOM 2872 C CD1 . ILE A 1 370 ? 12.253 17.778 9.131 1.00 32.09 ? 370 ILE A CD1 1 ATOM 2873 N N . GLY A 1 371 ? 8.075 18.805 11.027 1.00 25.31 ? 371 GLY A N 1 ATOM 2874 C CA . GLY A 1 371 ? 7.353 20.053 10.940 1.00 22.86 ? 371 GLY A CA 1 ATOM 2875 C C . GLY A 1 371 ? 7.005 20.607 12.308 1.00 26.85 ? 371 GLY A C 1 ATOM 2876 O O . GLY A 1 371 ? 7.314 20.009 13.339 1.00 28.19 ? 371 GLY A O 1 ATOM 2877 N N . PRO A 1 372 ? 6.328 21.757 12.336 1.00 30.91 ? 372 PRO A N 1 ATOM 2878 C CA . PRO A 1 372 ? 6.045 22.420 13.623 1.00 34.55 ? 372 PRO A CA 1 ATOM 2879 C C . PRO A 1 372 ? 5.389 21.526 14.662 1.00 39.04 ? 372 PRO A C 1 ATOM 2880 O O . PRO A 1 372 ? 5.619 21.717 15.863 1.00 38.13 ? 372 PRO A O 1 ATOM 2881 C CB . PRO A 1 372 ? 5.117 23.578 13.221 1.00 34.76 ? 372 PRO A CB 1 ATOM 2882 C CG . PRO A 1 372 ? 5.390 23.820 11.785 1.00 35.67 ? 372 PRO A CG 1 ATOM 2883 C CD . PRO A 1 372 ? 5.756 22.485 11.191 1.00 30.14 ? 372 PRO A CD 1 ATOM 2884 N N . ASP A 1 373 ? 4.598 20.538 14.249 1.00 33.71 ? 373 ASP A N 1 ATOM 2885 C CA . ASP A 1 373 ? 3.805 19.764 15.191 1.00 29.92 ? 373 ASP A CA 1 ATOM 2886 C C . ASP A 1 373 ? 4.458 18.452 15.604 1.00 34.89 ? 373 ASP A C 1 ATOM 2887 O O . ASP A 1 373 ? 3.876 17.712 16.403 1.00 32.75 ? 373 ASP A O 1 ATOM 2888 C CB . ASP A 1 373 ? 2.416 19.502 14.603 1.00 35.31 ? 373 ASP A CB 1 ATOM 2889 C CG . ASP A 1 373 ? 1.628 20.782 14.414 1.00 37.74 ? 373 ASP A CG 1 ATOM 2890 O OD1 . ASP A 1 373 ? 1.166 21.333 15.434 1.00 46.72 ? 373 ASP A OD1 1 ATOM 2891 O OD2 . ASP A 1 373 ? 1.493 21.253 13.264 1.00 35.80 ? 373 ASP A OD2 1 ATOM 2892 N N . PHE A 1 374 ? 5.649 18.150 15.106 1.00 28.76 ? 374 PHE A N 1 ATOM 2893 C CA . PHE A 1 374 ? 6.322 16.903 15.440 1.00 32.44 ? 374 PHE A CA 1 ATOM 2894 C C . PHE A 1 374 ? 7.608 17.197 16.194 1.00 28.86 ? 374 PHE A C 1 ATOM 2895 O O . PHE A 1 374 ? 8.295 18.179 15.904 1.00 33.57 ? 374 PHE A O 1 ATOM 2896 C CB . PHE A 1 374 ? 6.592 16.077 14.173 1.00 26.77 ? 374 PHE A CB 1 ATOM 2897 C CG . PHE A 1 374 ? 5.319 15.583 13.520 1.00 23.97 ? 374 PHE A CG 1 ATOM 2898 C CD1 . PHE A 1 374 ? 4.695 14.435 13.982 1.00 28.07 ? 374 PHE A CD1 1 ATOM 2899 C CD2 . PHE A 1 374 ? 4.723 16.309 12.505 1.00 29.44 ? 374 PHE A CD2 1 ATOM 2900 C CE1 . PHE A 1 374 ? 3.510 13.990 13.416 1.00 31.57 ? 374 PHE A CE1 1 ATOM 2901 C CE2 . PHE A 1 374 ? 3.531 15.876 11.931 1.00 24.11 ? 374 PHE A CE2 1 ATOM 2902 C CZ . PHE A 1 374 ? 2.919 14.725 12.394 1.00 23.31 ? 374 PHE A CZ 1 ATOM 2903 N N . LYS A 1 375 ? 7.909 16.348 17.175 1.00 31.69 ? 375 LYS A N 1 ATOM 2904 C CA . LYS A 1 375 ? 9.179 16.416 17.880 1.00 34.92 ? 375 LYS A CA 1 ATOM 2905 C C . LYS A 1 375 ? 10.330 16.192 16.908 1.00 43.36 ? 375 LYS A C 1 ATOM 2906 O O . LYS A 1 375 ? 10.160 15.642 15.816 1.00 36.66 ? 375 LYS A O 1 ATOM 2907 C CB . LYS A 1 375 ? 9.225 15.382 19.001 1.00 29.25 ? 375 LYS A CB 1 ATOM 2908 C CG . LYS A 1 375 ? 8.229 15.641 20.118 1.00 34.23 ? 375 LYS A CG 1 ATOM 2909 C CD . LYS A 1 375 ? 8.281 14.571 21.185 1.00 28.13 ? 375 LYS A CD 1 ATOM 2910 C CE . LYS A 1 375 ? 7.223 14.841 22.244 1.00 27.83 ? 375 LYS A CE 1 ATOM 2911 N NZ . LYS A 1 375 ? 6.970 13.694 23.142 1.00 36.84 ? 375 LYS A NZ 1 ATOM 2912 N N . SER A 1 376 ? 11.516 16.645 17.302 1.00 31.71 ? 376 SER A N 1 ATOM 2913 C CA . SER A 1 376 ? 12.680 16.559 16.437 1.00 33.50 ? 376 SER A CA 1 ATOM 2914 C C . SER A 1 376 ? 13.707 15.611 17.042 1.00 37.87 ? 376 SER A C 1 ATOM 2915 O O . SER A 1 376 ? 13.885 15.561 18.264 1.00 36.20 ? 376 SER A O 1 ATOM 2916 C CB . SER A 1 376 ? 13.302 17.940 16.208 1.00 39.59 ? 376 SER A CB 1 ATOM 2917 O OG . SER A 1 376 ? 13.644 18.546 17.438 1.00 51.95 ? 376 SER A OG 1 ATOM 2918 N N . ASN A 1 377 ? 14.365 14.851 16.165 1.00 31.62 ? 377 ASN A N 1 ATOM 2919 C CA . ASN A 1 377 ? 15.333 13.823 16.560 1.00 34.49 ? 377 ASN A CA 1 ATOM 2920 C C . ASN A 1 377 ? 14.705 12.822 17.530 1.00 35.90 ? 377 ASN A C 1 ATOM 2921 O O . ASN A 1 377 ? 15.311 12.419 18.524 1.00 33.40 ? 377 ASN A O 1 ATOM 2922 C CB . ASN A 1 377 ? 16.593 14.466 17.149 1.00 39.46 ? 377 ASN A CB 1 ATOM 2923 C CG . ASN A 1 377 ? 17.780 13.518 17.182 1.00 42.65 ? 377 ASN A CG 1 ATOM 2924 O OD1 . ASN A 1 377 ? 17.886 12.596 16.371 1.00 42.01 ? 377 ASN A OD1 1 ATOM 2925 N ND2 . ASN A 1 377 ? 18.679 13.740 18.129 1.00 43.63 ? 377 ASN A ND2 1 ATOM 2926 N N . PHE A 1 378 ? 13.476 12.403 17.230 1.00 31.52 ? 378 PHE A N 1 ATOM 2927 C CA . PHE A 1 378 ? 12.680 11.559 18.115 1.00 29.74 ? 378 PHE A CA 1 ATOM 2928 C C . PHE A 1 378 ? 12.482 10.196 17.460 1.00 33.66 ? 378 PHE A C 1 ATOM 2929 O O . PHE A 1 378 ? 11.874 10.107 16.387 1.00 30.19 ? 378 PHE A O 1 ATOM 2930 C CB . PHE A 1 378 ? 11.333 12.222 18.401 1.00 30.50 ? 378 PHE A CB 1 ATOM 2931 C CG . PHE A 1 378 ? 10.457 11.464 19.364 1.00 34.41 ? 378 PHE A CG 1 ATOM 2932 C CD1 . PHE A 1 378 ? 9.582 10.487 18.913 1.00 28.82 ? 378 PHE A CD1 1 ATOM 2933 C CD2 . PHE A 1 378 ? 10.482 11.755 20.720 1.00 31.85 ? 378 PHE A CD2 1 ATOM 2934 C CE1 . PHE A 1 378 ? 8.765 9.802 19.797 1.00 29.90 ? 378 PHE A CE1 1 ATOM 2935 C CE2 . PHE A 1 378 ? 9.668 11.081 21.608 1.00 32.60 ? 378 PHE A CE2 1 ATOM 2936 C CZ . PHE A 1 378 ? 8.806 10.106 21.148 1.00 32.42 ? 378 PHE A CZ 1 ATOM 2937 N N . ARG A 1 379 ? 12.993 9.142 18.104 1.00 31.79 ? 379 ARG A N 1 ATOM 2938 C CA . ARG A 1 379 ? 12.815 7.768 17.635 1.00 32.37 ? 379 ARG A CA 1 ATOM 2939 C C . ARG A 1 379 ? 11.579 7.182 18.307 1.00 29.93 ? 379 ARG A C 1 ATOM 2940 O O . ARG A 1 379 ? 11.596 6.886 19.507 1.00 32.46 ? 379 ARG A O 1 ATOM 2941 C CB . ARG A 1 379 ? 14.049 6.920 17.936 1.00 34.87 ? 379 ARG A CB 1 ATOM 2942 C CG . ARG A 1 379 ? 15.343 7.484 17.393 1.00 34.85 ? 379 ARG A CG 1 ATOM 2943 C CD . ARG A 1 379 ? 15.388 7.540 15.866 1.00 42.30 ? 379 ARG A CD 1 ATOM 2944 N NE . ARG A 1 379 ? 16.761 7.765 15.423 1.00 43.35 ? 379 ARG A NE 1 ATOM 2945 C CZ . ARG A 1 379 ? 17.330 8.963 15.312 1.00 38.24 ? 379 ARG A CZ 1 ATOM 2946 N NH1 . ARG A 1 379 ? 16.632 10.064 15.575 1.00 38.35 ? 379 ARG A NH1 1 ATOM 2947 N NH2 . ARG A 1 379 ? 18.596 9.060 14.920 1.00 40.99 ? 379 ARG A NH2 1 ATOM 2948 N N . ALA A 1 380 ? 10.508 7.008 17.538 1.00 30.97 ? 380 ALA A N 1 ATOM 2949 C CA . ALA A 1 380 ? 9.249 6.522 18.084 1.00 26.21 ? 380 ALA A CA 1 ATOM 2950 C C . ALA A 1 380 ? 9.150 5.008 17.960 1.00 26.52 ? 380 ALA A C 1 ATOM 2951 O O . ALA A 1 380 ? 9.707 4.401 17.036 1.00 23.34 ? 380 ALA A O 1 ATOM 2952 C CB . ALA A 1 380 ? 8.059 7.184 17.377 1.00 30.18 ? 380 ALA A CB 1 ATOM 2953 N N . ALA A 1 381 ? 8.421 4.406 18.914 1.00 25.72 ? 381 ALA A N 1 ATOM 2954 C CA . ALA A 1 381 ? 8.139 2.981 18.910 1.00 27.67 ? 381 ALA A CA 1 ATOM 2955 C C . ALA A 1 381 ? 7.348 2.606 17.654 1.00 23.04 ? 381 ALA A C 1 ATOM 2956 O O . ALA A 1 381 ? 6.708 3.463 17.036 1.00 22.73 ? 381 ALA A O 1 ATOM 2957 C CB . ALA A 1 381 ? 7.360 2.600 20.171 1.00 30.27 ? 381 ALA A CB 1 ATOM 2958 N N . PRO A 1 382 ? 7.396 1.334 17.242 1.00 24.99 ? 382 PRO A N 1 ATOM 2959 C CA . PRO A 1 382 ? 6.710 0.953 16.000 1.00 26.21 ? 382 PRO A CA 1 ATOM 2960 C C . PRO A 1 382 ? 5.199 1.123 16.103 1.00 25.19 ? 382 PRO A C 1 ATOM 2961 O O . PRO A 1 382 ? 4.599 0.954 17.166 1.00 29.28 ? 382 PRO A O 1 ATOM 2962 C CB . PRO A 1 382 ? 7.109 -0.515 15.794 1.00 25.76 ? 382 PRO A CB 1 ATOM 2963 C CG . PRO A 1 382 ? 7.735 -0.964 17.052 1.00 24.67 ? 382 PRO A CG 1 ATOM 2964 C CD . PRO A 1 382 ? 8.209 0.234 17.804 1.00 21.63 ? 382 PRO A CD 1 ATOM 2965 N N . ILE A 1 383 ? 4.590 1.502 14.980 1.00 25.66 ? 383 ILE A N 1 ATOM 2966 C CA . ILE A 1 383 ? 3.150 1.701 14.894 1.00 23.74 ? 383 ILE A CA 1 ATOM 2967 C C . ILE A 1 383 ? 2.592 0.804 13.790 1.00 24.03 ? 383 ILE A C 1 ATOM 2968 O O . ILE A 1 383 ? 3.331 0.142 13.056 1.00 20.84 ? 383 ILE A O 1 ATOM 2969 C CB . ILE A 1 383 ? 2.771 3.175 14.655 1.00 26.62 ? 383 ILE A CB 1 ATOM 2970 C CG1 . ILE A 1 383 ? 3.182 3.621 13.256 1.00 21.82 ? 383 ILE A CG1 1 ATOM 2971 C CG2 . ILE A 1 383 ? 3.450 4.072 15.696 1.00 28.87 ? 383 ILE A CG2 1 ATOM 2972 C CD1 . ILE A 1 383 ? 2.783 5.049 12.931 1.00 26.07 ? 383 ILE A CD1 1 ATOM 2973 N N . ARG A 1 384 ? 1.263 0.778 13.697 1.00 23.14 ? 384 ARG A N 1 ATOM 2974 C CA . ARG A 1 384 ? 0.550 -0.019 12.713 1.00 21.15 ? 384 ARG A CA 1 ATOM 2975 C C . ARG A 1 384 ? -0.066 0.908 11.679 1.00 20.67 ? 384 ARG A C 1 ATOM 2976 O O . ARG A 1 384 ? -0.318 2.083 11.946 1.00 19.55 ? 384 ARG A O 1 ATOM 2977 C CB . ARG A 1 384 ? -0.550 -0.866 13.361 1.00 24.16 ? 384 ARG A CB 1 ATOM 2978 C CG . ARG A 1 384 ? -0.039 -1.787 14.474 1.00 29.36 ? 384 ARG A CG 1 ATOM 2979 C CD . ARG A 1 384 ? -1.009 -2.915 14.787 1.00 37.11 ? 384 ARG A CD 1 ATOM 2980 N NE . ARG A 1 384 ? -0.326 -3.969 15.545 1.00 40.95 ? 384 ARG A NE 1 ATOM 2981 C CZ . ARG A 1 384 ? 0.113 -5.112 15.019 1.00 43.98 ? 384 ARG A CZ 1 ATOM 2982 N NH1 . ARG A 1 384 ? -0.081 -5.375 13.730 1.00 33.29 ? 384 ARG A NH1 1 ATOM 2983 N NH2 . ARG A 1 384 ? 0.737 -6.002 15.790 1.00 41.15 ? 384 ARG A NH2 1 ATOM 2984 N N . SER A 1 385 ? -0.307 0.359 10.490 1.00 19.12 ? 385 SER A N 1 ATOM 2985 C CA A SER A 1 385 ? -0.908 1.145 9.410 0.50 19.43 ? 385 SER A CA 1 ATOM 2986 C CA B SER A 1 385 ? -0.893 1.165 9.421 0.50 19.43 ? 385 SER A CA 1 ATOM 2987 C C . SER A 1 385 ? -2.185 1.849 9.857 1.00 20.27 ? 385 SER A C 1 ATOM 2988 O O . SER A 1 385 ? -2.453 2.990 9.460 1.00 22.26 ? 385 SER A O 1 ATOM 2989 C CB A SER A 1 385 ? -1.193 0.243 8.207 0.50 19.08 ? 385 SER A CB 1 ATOM 2990 C CB B SER A 1 385 ? -1.120 0.297 8.182 0.50 19.10 ? 385 SER A CB 1 ATOM 2991 O OG A SER A 1 385 ? -1.446 1.015 7.047 0.50 17.67 ? 385 SER A OG 1 ATOM 2992 O OG B SER A 1 385 ? 0.120 0.026 7.549 0.50 17.40 ? 385 SER A OG 1 ATOM 2993 N N . VAL A 1 386 ? -2.994 1.179 10.686 1.00 16.86 ? 386 VAL A N 1 ATOM 2994 C CA . VAL A 1 386 ? -4.241 1.783 11.155 1.00 19.79 ? 386 VAL A CA 1 ATOM 2995 C C . VAL A 1 386 ? -4.014 2.978 12.073 1.00 17.94 ? 386 VAL A C 1 ATOM 2996 O O . VAL A 1 386 ? -4.945 3.745 12.307 1.00 18.87 ? 386 VAL A O 1 ATOM 2997 C CB . VAL A 1 386 ? -5.148 0.773 11.895 1.00 21.45 ? 386 VAL A CB 1 ATOM 2998 C CG1 . VAL A 1 386 ? -5.755 -0.264 10.918 1.00 18.72 ? 386 VAL A CG1 1 ATOM 2999 C CG2 . VAL A 1 386 ? -4.399 0.079 13.043 1.00 21.83 ? 386 VAL A CG2 1 ATOM 3000 N N . ASP A 1 387 ? -2.800 3.179 12.578 1.00 20.37 ? 387 ASP A N 1 ATOM 3001 C CA . ASP A 1 387 ? -2.556 4.274 13.519 1.00 21.95 ? 387 ASP A CA 1 ATOM 3002 C C . ASP A 1 387 ? -2.309 5.627 12.847 1.00 21.70 ? 387 ASP A C 1 ATOM 3003 O O . ASP A 1 387 ? -2.383 6.665 13.524 1.00 24.08 ? 387 ASP A O 1 ATOM 3004 C CB . ASP A 1 387 ? -1.353 3.942 14.393 1.00 25.60 ? 387 ASP A CB 1 ATOM 3005 C CG . ASP A 1 387 ? -1.565 2.700 15.232 1.00 20.46 ? 387 ASP A CG 1 ATOM 3006 O OD1 . ASP A 1 387 ? -2.725 2.380 15.565 1.00 27.57 ? 387 ASP A OD1 1 ATOM 3007 O OD2 . ASP A 1 387 ? -0.563 2.053 15.567 1.00 26.00 ? 387 ASP A OD2 1 ATOM 3008 N N . VAL A 1 388 ? -2.038 5.642 11.540 1.00 19.75 ? 388 VAL A N 1 ATOM 3009 C CA . VAL A 1 388 ? -1.539 6.838 10.868 1.00 19.74 ? 388 VAL A CA 1 ATOM 3010 C C . VAL A 1 388 ? -2.645 7.875 10.698 1.00 22.34 ? 388 VAL A C 1 ATOM 3011 O O . VAL A 1 388 ? -2.409 9.088 10.812 1.00 21.46 ? 388 VAL A O 1 ATOM 3012 C CB . VAL A 1 388 ? -0.905 6.416 9.525 1.00 20.22 ? 388 VAL A CB 1 ATOM 3013 C CG1 . VAL A 1 388 ? -0.639 7.612 8.619 1.00 21.54 ? 388 VAL A CG1 1 ATOM 3014 C CG2 . VAL A 1 388 ? 0.386 5.622 9.794 1.00 22.12 ? 388 VAL A CG2 1 ATOM 3015 N N . TYR A 1 389 ? -3.870 7.409 10.447 1.00 20.69 ? 389 TYR A N 1 ATOM 3016 C CA . TYR A 1 389 ? -5.005 8.281 10.156 1.00 18.57 ? 389 TYR A CA 1 ATOM 3017 C C . TYR A 1 389 ? -5.245 9.298 11.262 1.00 19.92 ? 389 TYR A C 1 ATOM 3018 O O . TYR A 1 389 ? -5.461 10.482 10.984 1.00 19.61 ? 389 TYR A O 1 ATOM 3019 C CB . TYR A 1 389 ? -6.228 7.395 9.945 1.00 19.63 ? 389 TYR A CB 1 ATOM 3020 C CG . TYR A 1 389 ? -7.577 8.048 9.795 1.00 21.81 ? 389 TYR A CG 1 ATOM 3021 C CD1 . TYR A 1 389 ? -8.004 8.536 8.563 1.00 20.34 ? 389 TYR A CD1 1 ATOM 3022 C CD2 . TYR A 1 389 ? -8.466 8.075 10.860 1.00 21.59 ? 389 TYR A CD2 1 ATOM 3023 C CE1 . TYR A 1 389 ? -9.283 9.096 8.411 1.00 20.37 ? 389 TYR A CE1 1 ATOM 3024 C CE2 . TYR A 1 389 ? -9.723 8.615 10.725 1.00 26.83 ? 389 TYR A CE2 1 ATOM 3025 C CZ . TYR A 1 389 ? -10.127 9.124 9.501 1.00 23.16 ? 389 TYR A CZ 1 ATOM 3026 O OH . TYR A 1 389 ? -11.381 9.661 9.370 1.00 22.95 ? 389 TYR A OH 1 ATOM 3027 N N . ASN A 1 390 ? -5.214 8.846 12.527 1.00 20.60 ? 390 ASN A N 1 ATOM 3028 C CA . ASN A 1 390 ? -5.433 9.758 13.656 1.00 24.59 ? 390 ASN A CA 1 ATOM 3029 C C . ASN A 1 390 ? -4.406 10.883 13.657 1.00 24.77 ? 390 ASN A C 1 ATOM 3030 O O . ASN A 1 390 ? -4.732 12.029 13.984 1.00 25.46 ? 390 ASN A O 1 ATOM 3031 C CB . ASN A 1 390 ? -5.368 9.003 14.993 1.00 25.52 ? 390 ASN A CB 1 ATOM 3032 C CG . ASN A 1 390 ? -6.661 8.262 15.342 1.00 24.25 ? 390 ASN A CG 1 ATOM 3033 O OD1 . ASN A 1 390 ? -7.750 8.679 14.967 1.00 28.75 ? 390 ASN A OD1 1 ATOM 3034 N ND2 . ASN A 1 390 ? -6.532 7.154 16.077 1.00 26.72 ? 390 ASN A ND2 1 ATOM 3035 N N . ILE A 1 391 ? -3.152 10.568 13.319 1.00 24.86 ? 391 ILE A N 1 ATOM 3036 C CA . ILE A 1 391 ? -2.107 11.589 13.265 1.00 25.34 ? 391 ILE A CA 1 ATOM 3037 C C . ILE A 1 391 ? -2.413 12.593 12.172 1.00 27.24 ? 391 ILE A C 1 ATOM 3038 O O . ILE A 1 391 ? -2.336 13.815 12.374 1.00 24.44 ? 391 ILE A O 1 ATOM 3039 C CB . ILE A 1 391 ? -0.728 10.942 13.027 1.00 27.71 ? 391 ILE A CB 1 ATOM 3040 C CG1 . ILE A 1 391 ? -0.454 9.830 14.028 1.00 23.18 ? 391 ILE A CG1 1 ATOM 3041 C CG2 . ILE A 1 391 ? 0.367 12.023 12.986 1.00 29.90 ? 391 ILE A CG2 1 ATOM 3042 C CD1 . ILE A 1 391 ? 0.786 8.996 13.691 1.00 28.68 ? 391 ILE A CD1 1 ATOM 3043 N N . MET A 1 392 ? -2.708 12.090 10.972 1.00 19.29 ? 392 MET A N 1 ATOM 3044 C CA . MET A 1 392 ? -2.977 12.976 9.850 1.00 19.25 ? 392 MET A CA 1 ATOM 3045 C C . MET A 1 392 ? -4.157 13.887 10.151 1.00 23.65 ? 392 MET A C 1 ATOM 3046 O O . MET A 1 392 ? -4.111 15.094 9.878 1.00 25.71 ? 392 MET A O 1 ATOM 3047 C CB . MET A 1 392 ? -3.240 12.149 8.587 1.00 21.00 ? 392 MET A CB 1 ATOM 3048 C CG . MET A 1 392 ? -2.015 11.430 8.056 1.00 18.98 ? 392 MET A CG 1 ATOM 3049 S SD . MET A 1 392 ? -2.299 10.826 6.365 1.00 21.27 ? 392 MET A SD 1 ATOM 3050 C CE . MET A 1 392 ? -3.533 9.556 6.653 1.00 22.65 ? 392 MET A CE 1 ATOM 3051 N N . ALA A 1 393 ? -5.223 13.324 10.724 1.00 23.57 ? 393 ALA A N 1 ATOM 3052 C CA . ALA A 1 393 ? -6.417 14.121 11.001 1.00 25.17 ? 393 ALA A CA 1 ATOM 3053 C C . ALA A 1 393 ? -6.129 15.185 12.048 1.00 27.27 ? 393 ALA A C 1 ATOM 3054 O O . ALA A 1 393 ? -6.612 16.321 11.946 1.00 29.76 ? 393 ALA A O 1 ATOM 3055 C CB . ALA A 1 393 ? -7.546 13.213 11.475 1.00 25.81 ? 393 ALA A CB 1 ATOM 3056 N N . HIS A 1 394 ? -5.360 14.819 13.071 1.00 26.21 ? 394 HIS A N 1 ATOM 3057 C CA . HIS A 1 394 ? -5.016 15.752 14.139 1.00 33.62 ? 394 HIS A CA 1 ATOM 3058 C C . HIS A 1 394 ? -4.263 16.955 13.595 1.00 30.24 ? 394 HIS A C 1 ATOM 3059 O O . HIS A 1 394 ? -4.656 18.103 13.828 1.00 29.56 ? 394 HIS A O 1 ATOM 3060 C CB . HIS A 1 394 ? -4.180 15.044 15.201 1.00 33.86 ? 394 HIS A CB 1 ATOM 3061 C CG . HIS A 1 394 ? -3.889 15.894 16.400 1.00 40.17 ? 394 HIS A CG 1 ATOM 3062 N ND1 . HIS A 1 394 ? -2.689 16.550 16.578 1.00 41.33 ? 394 HIS A ND1 1 ATOM 3063 C CD2 . HIS A 1 394 ? -4.646 16.197 17.482 1.00 39.49 ? 394 HIS A CD2 1 ATOM 3064 C CE1 . HIS A 1 394 ? -2.721 17.224 17.715 1.00 38.34 ? 394 HIS A CE1 1 ATOM 3065 N NE2 . HIS A 1 394 ? -3.897 17.026 18.283 1.00 44.71 ? 394 HIS A NE2 1 ATOM 3066 N N . VAL A 1 395 ? -3.173 16.718 12.859 1.00 26.69 ? 395 VAL A N 1 ATOM 3067 C CA . VAL A 1 395 ? -2.379 17.856 12.397 1.00 28.05 ? 395 VAL A CA 1 ATOM 3068 C C . VAL A 1 395 ? -3.042 18.588 11.243 1.00 30.72 ? 395 VAL A C 1 ATOM 3069 O O . VAL A 1 395 ? -2.679 19.737 10.971 1.00 31.33 ? 395 VAL A O 1 ATOM 3070 C CB . VAL A 1 395 ? -0.941 17.450 12.017 1.00 27.85 ? 395 VAL A CB 1 ATOM 3071 C CG1 . VAL A 1 395 ? -0.183 16.968 13.252 1.00 26.04 ? 395 VAL A CG1 1 ATOM 3072 C CG2 . VAL A 1 395 ? -0.940 16.381 10.914 1.00 26.90 ? 395 VAL A CG2 1 ATOM 3073 N N . ALA A 1 396 ? -4.014 17.969 10.560 1.00 26.84 ? 396 ALA A N 1 ATOM 3074 C CA . ALA A 1 396 ? -4.814 18.688 9.578 1.00 28.05 ? 396 ALA A CA 1 ATOM 3075 C C . ALA A 1 396 ? -5.959 19.458 10.215 1.00 29.55 ? 396 ALA A C 1 ATOM 3076 O O . ALA A 1 396 ? -6.641 20.213 9.517 1.00 30.35 ? 396 ALA A O 1 ATOM 3077 C CB . ALA A 1 396 ? -5.397 17.728 8.525 1.00 28.48 ? 396 ALA A CB 1 ATOM 3078 N N . GLY A 1 397 ? -6.205 19.256 11.503 1.00 31.14 ? 397 GLY A N 1 ATOM 3079 C CA . GLY A 1 397 ? -7.255 19.981 12.183 1.00 33.95 ? 397 GLY A CA 1 ATOM 3080 C C . GLY A 1 397 ? -8.653 19.480 11.923 1.00 39.12 ? 397 GLY A C 1 ATOM 3081 O O . GLY A 1 397 ? -9.596 20.272 11.964 1.00 32.23 ? 397 GLY A O 1 ATOM 3082 N N . ILE A 1 398 ? -8.828 18.183 11.673 1.00 31.67 ? 398 ILE A N 1 ATOM 3083 C CA . ILE A 1 398 ? -10.153 17.640 11.409 1.00 35.03 ? 398 ILE A CA 1 ATOM 3084 C C . ILE A 1 398 ? -10.415 16.489 12.368 1.00 36.78 ? 398 ILE A C 1 ATOM 3085 O O . ILE A 1 398 ? -9.502 15.754 12.757 1.00 31.54 ? 398 ILE A O 1 ATOM 3086 C CB . ILE A 1 398 ? -10.314 17.193 9.933 1.00 39.66 ? 398 ILE A CB 1 ATOM 3087 C CG1 . ILE A 1 398 ? -11.781 16.872 9.632 1.00 40.35 ? 398 ILE A CG1 1 ATOM 3088 C CG2 . ILE A 1 398 ? -9.401 16.009 9.614 1.00 33.53 ? 398 ILE A CG2 1 ATOM 3089 C CD1 . ILE A 1 398 ? -12.141 16.935 8.164 1.00 39.10 ? 398 ILE A CD1 1 ATOM 3090 N N . THR A 1 399 ? -11.666 16.350 12.776 1.00 29.70 ? 399 THR A N 1 ATOM 3091 C CA . THR A 1 399 ? -12.011 15.282 13.700 1.00 31.03 ? 399 THR A CA 1 ATOM 3092 C C . THR A 1 399 ? -11.949 13.952 12.962 1.00 26.72 ? 399 THR A C 1 ATOM 3093 O O . THR A 1 399 ? -12.563 13.823 11.898 1.00 29.52 ? 399 THR A O 1 ATOM 3094 C CB . THR A 1 399 ? -13.401 15.507 14.281 1.00 36.33 ? 399 THR A CB 1 ATOM 3095 O OG1 . THR A 1 399 ? -13.398 16.715 15.056 1.00 37.48 ? 399 THR A OG1 1 ATOM 3096 C CG2 . THR A 1 399 ? -13.785 14.352 15.167 1.00 32.20 ? 399 THR A CG2 1 ATOM 3097 N N . PRO A 1 400 ? -11.221 12.957 13.467 1.00 31.91 ? 400 PRO A N 1 ATOM 3098 C CA . PRO A 1 400 ? -11.199 11.656 12.787 1.00 28.75 ? 400 PRO A CA 1 ATOM 3099 C C . PRO A 1 400 ? -12.521 10.920 12.940 1.00 32.77 ? 400 PRO A C 1 ATOM 3100 O O . PRO A 1 400 ? -13.137 10.923 14.009 1.00 30.80 ? 400 PRO A O 1 ATOM 3101 C CB . PRO A 1 400 ? -10.069 10.903 13.499 1.00 29.96 ? 400 PRO A CB 1 ATOM 3102 C CG . PRO A 1 400 ? -9.944 11.572 14.830 1.00 33.76 ? 400 PRO A CG 1 ATOM 3103 C CD . PRO A 1 400 ? -10.277 13.008 14.595 1.00 27.88 ? 400 PRO A CD 1 ATOM 3104 N N . LEU A 1 401 ? -12.949 10.268 11.861 1.00 28.17 ? 401 LEU A N 1 ATOM 3105 C CA . LEU A 1 401 ? -14.037 9.308 11.970 1.00 29.06 ? 401 LEU A CA 1 ATOM 3106 C C . LEU A 1 401 ? -13.582 8.131 12.839 1.00 32.93 ? 401 LEU A C 1 ATOM 3107 O O . LEU A 1 401 ? -12.381 7.857 12.932 1.00 28.22 ? 401 LEU A O 1 ATOM 3108 C CB . LEU A 1 401 ? -14.472 8.821 10.582 1.00 29.59 ? 401 LEU A CB 1 ATOM 3109 C CG . LEU A 1 401 ? -14.903 9.919 9.599 1.00 31.51 ? 401 LEU A CG 1 ATOM 3110 C CD1 . LEU A 1 401 ? -15.457 9.385 8.264 1.00 26.06 ? 401 LEU A CD1 1 ATOM 3111 C CD2 . LEU A 1 401 ? -15.902 10.885 10.240 1.00 35.90 ? 401 LEU A CD2 1 ATOM 3112 N N . PRO A 1 402 ? -14.515 7.449 13.515 1.00 27.61 ? 402 PRO A N 1 ATOM 3113 C CA . PRO A 1 402 ? -14.145 6.304 14.363 1.00 31.52 ? 402 PRO A CA 1 ATOM 3114 C C . PRO A 1 402 ? -13.358 5.268 13.575 1.00 24.19 ? 402 PRO A C 1 ATOM 3115 O O . PRO A 1 402 ? -13.716 4.923 12.451 1.00 27.32 ? 402 PRO A O 1 ATOM 3116 C CB . PRO A 1 402 ? -15.500 5.750 14.818 1.00 31.14 ? 402 PRO A CB 1 ATOM 3117 C CG . PRO A 1 402 ? -16.454 6.897 14.694 1.00 30.01 ? 402 PRO A CG 1 ATOM 3118 C CD . PRO A 1 402 ? -15.961 7.747 13.565 1.00 32.10 ? 402 PRO A CD 1 ATOM 3119 N N . ASN A 1 403 ? -12.277 4.764 14.171 1.00 26.93 ? 403 ASN A N 1 ATOM 3120 C CA . ASN A 1 403 ? -11.359 3.921 13.417 1.00 24.03 ? 403 ASN A CA 1 ATOM 3121 C C . ASN A 1 403 ? -10.667 2.948 14.373 1.00 29.27 ? 403 ASN A C 1 ATOM 3122 O O . ASN A 1 403 ? -11.000 2.860 15.558 1.00 27.14 ? 403 ASN A O 1 ATOM 3123 C CB . ASN A 1 403 ? -10.372 4.789 12.612 1.00 21.10 ? 403 ASN A CB 1 ATOM 3124 C CG . ASN A 1 403 ? -9.456 5.650 13.493 1.00 27.67 ? 403 ASN A CG 1 ATOM 3125 O OD1 . ASN A 1 403 ? -8.394 5.195 13.927 1.00 25.41 ? 403 ASN A OD1 1 ATOM 3126 N ND2 . ASN A 1 403 ? -9.859 6.906 13.742 1.00 24.74 ? 403 ASN A ND2 1 ATOM 3127 N N . ASN A 1 404 ? -9.717 2.187 13.837 1.00 25.05 ? 404 ASN A N 1 ATOM 3128 C CA . ASN A 1 404 ? -9.063 1.114 14.581 1.00 20.73 ? 404 ASN A CA 1 ATOM 3129 C C . ASN A 1 404 ? -7.663 1.496 15.027 1.00 23.51 ? 404 ASN A C 1 ATOM 3130 O O . ASN A 1 404 ? -6.967 0.671 15.626 1.00 24.33 ? 404 ASN A O 1 ATOM 3131 C CB . ASN A 1 404 ? -9.034 -0.171 13.743 1.00 27.93 ? 404 ASN A CB 1 ATOM 3132 C CG . ASN A 1 404 ? -10.410 -0.549 13.231 1.00 32.49 ? 404 ASN A CG 1 ATOM 3133 O OD1 . ASN A 1 404 ? -10.627 -0.719 12.021 1.00 22.69 ? 404 ASN A OD1 1 ATOM 3134 N ND2 . ASN A 1 404 ? -11.363 -0.676 14.157 1.00 29.99 ? 404 ASN A ND2 1 ATOM 3135 N N . GLY A 1 405 ? -7.250 2.739 14.784 1.00 21.99 ? 405 GLY A N 1 ATOM 3136 C CA . GLY A 1 405 ? -5.975 3.198 15.277 1.00 22.95 ? 405 GLY A CA 1 ATOM 3137 C C . GLY A 1 405 ? -5.970 3.350 16.785 1.00 30.62 ? 405 GLY A C 1 ATOM 3138 O O . GLY A 1 405 ? -7.004 3.529 17.436 1.00 30.62 ? 405 GLY A O 1 ATOM 3139 N N . SER A 1 406 ? -4.771 3.265 17.345 1.00 27.60 ? 406 SER A N 1 ATOM 3140 C CA . SER A 1 406 ? -4.532 3.445 18.772 1.00 33.06 ? 406 SER A CA 1 ATOM 3141 C C . SER A 1 406 ? -3.810 4.773 18.956 1.00 30.37 ? 406 SER A C 1 ATOM 3142 O O . SER A 1 406 ? -2.654 4.916 18.546 1.00 28.51 ? 406 SER A O 1 ATOM 3143 C CB . SER A 1 406 ? -3.717 2.276 19.332 1.00 28.68 ? 406 SER A CB 1 ATOM 3144 O OG . SER A 1 406 ? -3.214 2.573 20.620 1.00 32.20 ? 406 SER A OG 1 ATOM 3145 N N . TRP A 1 407 ? -4.503 5.756 19.541 1.00 28.04 ? 407 TRP A N 1 ATOM 3146 C CA . TRP A 1 407 ? -3.855 7.016 19.883 1.00 31.77 ? 407 TRP A CA 1 ATOM 3147 C C . TRP A 1 407 ? -2.698 6.795 20.855 1.00 32.55 ? 407 TRP A C 1 ATOM 3148 O O . TRP A 1 407 ? -1.662 7.463 20.762 1.00 33.93 ? 407 TRP A O 1 ATOM 3149 C CB . TRP A 1 407 ? -4.891 7.974 20.470 1.00 36.73 ? 407 TRP A CB 1 ATOM 3150 C CG . TRP A 1 407 ? -4.462 9.404 20.643 1.00 37.44 ? 407 TRP A CG 1 ATOM 3151 C CD1 . TRP A 1 407 ? -4.364 10.091 21.825 1.00 42.15 ? 407 TRP A CD1 1 ATOM 3152 C CD2 . TRP A 1 407 ? -4.123 10.342 19.610 1.00 37.07 ? 407 TRP A CD2 1 ATOM 3153 N NE1 . TRP A 1 407 ? -3.978 11.391 21.590 1.00 39.18 ? 407 TRP A NE1 1 ATOM 3154 C CE2 . TRP A 1 407 ? -3.821 11.571 20.241 1.00 43.25 ? 407 TRP A CE2 1 ATOM 3155 C CE3 . TRP A 1 407 ? -4.036 10.262 18.217 1.00 35.89 ? 407 TRP A CE3 1 ATOM 3156 C CZ2 . TRP A 1 407 ? -3.436 12.709 19.525 1.00 38.73 ? 407 TRP A CZ2 1 ATOM 3157 C CZ3 . TRP A 1 407 ? -3.656 11.397 17.507 1.00 34.32 ? 407 TRP A CZ3 1 ATOM 3158 C CH2 . TRP A 1 407 ? -3.364 12.603 18.163 1.00 34.58 ? 407 TRP A CH2 1 ATOM 3159 N N . SER A 1 408 ? -2.841 5.844 21.778 1.00 33.85 ? 408 SER A N 1 ATOM 3160 C CA . SER A 1 408 ? -1.762 5.586 22.730 1.00 34.85 ? 408 SER A CA 1 ATOM 3161 C C . SER A 1 408 ? -0.477 5.161 22.022 1.00 31.57 ? 408 SER A C 1 ATOM 3162 O O . SER A 1 408 ? 0.628 5.456 22.495 1.00 30.32 ? 408 SER A O 1 ATOM 3163 C CB . SER A 1 408 ? -2.199 4.535 23.758 1.00 33.79 ? 408 SER A CB 1 ATOM 3164 O OG . SER A 1 408 ? -2.619 3.308 23.170 1.00 31.09 ? 408 SER A OG 1 ATOM 3165 N N . ARG A 1 409 ? -0.594 4.489 20.873 1.00 29.40 ? 409 ARG A N 1 ATOM 3166 C CA . ARG A 1 409 ? 0.602 4.031 20.178 1.00 28.82 ? 409 ARG A CA 1 ATOM 3167 C C . ARG A 1 409 ? 1.344 5.139 19.436 1.00 31.74 ? 409 ARG A C 1 ATOM 3168 O O . ARG A 1 409 ? 2.480 4.900 19.009 1.00 31.64 ? 409 ARG A O 1 ATOM 3169 C CB . ARG A 1 409 ? 0.252 2.902 19.189 1.00 28.22 ? 409 ARG A CB 1 ATOM 3170 C CG . ARG A 1 409 ? -0.027 1.560 19.841 1.00 27.47 ? 409 ARG A CG 1 ATOM 3171 C CD . ARG A 1 409 ? 0.200 0.406 18.844 1.00 37.97 ? 409 ARG A CD 1 ATOM 3172 N NE . ARG A 1 409 ? -0.833 0.412 17.820 1.00 34.77 ? 409 ARG A NE 1 ATOM 3173 C CZ . ARG A 1 409 ? -1.915 -0.352 17.855 1.00 32.64 ? 409 ARG A CZ 1 ATOM 3174 N NH1 . ARG A 1 409 ? -2.091 -1.208 18.858 1.00 40.52 ? 409 ARG A NH1 1 ATOM 3175 N NH2 . ARG A 1 409 ? -2.814 -0.266 16.890 1.00 27.68 ? 409 ARG A NH2 1 ATOM 3176 N N . VAL A 1 410 ? 0.764 6.340 19.294 1.00 26.79 ? 410 VAL A N 1 ATOM 3177 C CA . VAL A 1 410 ? 1.357 7.378 18.450 1.00 27.90 ? 410 VAL A CA 1 ATOM 3178 C C . VAL A 1 410 ? 1.494 8.727 19.150 1.00 33.00 ? 410 VAL A C 1 ATOM 3179 O O . VAL A 1 410 ? 2.229 9.594 18.673 1.00 35.95 ? 410 VAL A O 1 ATOM 3180 C CB . VAL A 1 410 ? 0.550 7.583 17.148 1.00 33.16 ? 410 VAL A CB 1 ATOM 3181 C CG1 . VAL A 1 410 ? 0.233 6.250 16.478 1.00 27.84 ? 410 VAL A CG1 1 ATOM 3182 C CG2 . VAL A 1 410 ? -0.733 8.373 17.413 1.00 33.89 ? 410 VAL A CG2 1 ATOM 3183 N N . VAL A 1 411 ? 0.787 8.931 20.266 1.00 39.77 ? 411 VAL A N 1 ATOM 3184 C CA . VAL A 1 411 ? 0.621 10.289 20.797 1.00 36.80 ? 411 VAL A CA 1 ATOM 3185 C C . VAL A 1 411 ? 1.957 10.935 21.169 1.00 36.92 ? 411 VAL A C 1 ATOM 3186 O O . VAL A 1 411 ? 2.114 12.156 21.041 1.00 38.07 ? 411 VAL A O 1 ATOM 3187 C CB . VAL A 1 411 ? -0.354 10.284 21.994 1.00 33.08 ? 411 VAL A CB 1 ATOM 3188 C CG1 . VAL A 1 411 ? 0.234 9.546 23.193 1.00 34.87 ? 411 VAL A CG1 1 ATOM 3189 C CG2 . VAL A 1 411 ? -0.745 11.711 22.360 1.00 36.92 ? 411 VAL A CG2 1 ATOM 3190 N N . SER A 1 412 ? 2.949 10.146 21.593 1.00 39.46 ? 412 SER A N 1 ATOM 3191 C CA . SER A 1 412 ? 4.177 10.733 22.121 1.00 34.76 ? 412 SER A CA 1 ATOM 3192 C C . SER A 1 412 ? 5.081 11.345 21.050 1.00 36.84 ? 412 SER A C 1 ATOM 3193 O O . SER A 1 412 ? 6.062 12.007 21.408 1.00 32.47 ? 412 SER A O 1 ATOM 3194 C CB . SER A 1 412 ? 4.949 9.688 22.938 1.00 39.52 ? 412 SER A CB 1 ATOM 3195 O OG . SER A 1 412 ? 5.481 8.657 22.128 1.00 42.24 ? 412 SER A OG 1 ATOM 3196 N N . MET A 1 413 ? 4.782 11.169 19.756 1.00 36.04 ? 413 MET A N 1 ATOM 3197 C CA . MET A 1 413 ? 5.575 11.822 18.715 1.00 30.64 ? 413 MET A CA 1 ATOM 3198 C C . MET A 1 413 ? 5.153 13.263 18.459 1.00 28.85 ? 413 MET A C 1 ATOM 3199 O O . MET A 1 413 ? 5.882 13.992 17.775 1.00 30.72 ? 413 MET A O 1 ATOM 3200 C CB . MET A 1 413 ? 5.498 11.043 17.391 1.00 28.46 ? 413 MET A CB 1 ATOM 3201 C CG . MET A 1 413 ? 4.170 11.187 16.671 1.00 30.85 ? 413 MET A CG 1 ATOM 3202 S SD . MET A 1 413 ? 4.121 10.336 15.066 1.00 31.29 ? 413 MET A SD 1 ATOM 3203 C CE . MET A 1 413 ? 4.352 8.620 15.561 1.00 25.53 ? 413 MET A CE 1 ATOM 3204 N N . LEU A 1 414 ? 4.010 13.692 18.978 1.00 31.63 ? 414 LEU A N 1 ATOM 3205 C CA . LEU A 1 414 ? 3.524 15.048 18.755 1.00 28.43 ? 414 LEU A CA 1 ATOM 3206 C C . LEU A 1 414 ? 4.050 16.011 19.814 1.00 36.00 ? 414 LEU A C 1 ATOM 3207 O O . LEU A 1 414 ? 4.178 15.660 20.989 1.00 42.12 ? 414 LEU A O 1 ATOM 3208 C CB . LEU A 1 414 ? 1.996 15.073 18.764 1.00 33.43 ? 414 LEU A CB 1 ATOM 3209 C CG . LEU A 1 414 ? 1.273 14.346 17.626 1.00 32.79 ? 414 LEU A CG 1 ATOM 3210 C CD1 . LEU A 1 414 ? -0.229 14.461 17.810 1.00 38.18 ? 414 LEU A CD1 1 ATOM 3211 C CD2 . LEU A 1 414 ? 1.676 14.933 16.280 1.00 34.54 ? 414 LEU A CD2 1 ATOM 3212 N N . LYS A 1 415 ? 4.345 17.238 19.385 1.00 35.17 ? 415 LYS A N 1 ATOM 3213 C CA . LYS A 1 415 ? 4.760 18.296 20.306 1.00 41.03 ? 415 LYS A CA 1 ATOM 3214 C C . LYS A 1 415 ? 3.622 18.696 21.245 1.00 45.07 ? 415 LYS A C 1 ATOM 3215 O O . LYS A 1 415 ? 2.592 19.212 20.794 1.00 51.28 ? 415 LYS A O 1 ATOM 3216 C CB . LYS A 1 415 ? 5.239 19.522 19.536 1.00 37.54 ? 415 LYS A CB 1 ATOM 3217 C CG . LYS A 1 415 ? 6.680 19.459 19.084 1.00 39.47 ? 415 LYS A CG 1 ATOM 3218 C CD . LYS A 1 415 ? 7.121 20.806 18.519 1.00 51.33 ? 415 LYS A CD 1 ATOM 3219 C CE . LYS A 1 415 ? 8.504 20.725 17.882 1.00 50.47 ? 415 LYS A CE 1 ATOM 3220 N NZ . LYS A 1 415 ? 8.713 21.796 16.859 1.00 54.51 ? 415 LYS A NZ 1 ATOM 3221 N N . HIS B 1 23 ? 9.141 7.604 45.818 1.00 48.52 ? 23 HIS B N 1 ATOM 3222 C CA . HIS B 1 23 ? 9.257 6.391 44.994 1.00 41.35 ? 23 HIS B CA 1 ATOM 3223 C C . HIS B 1 23 ? 8.626 5.190 45.687 1.00 42.74 ? 23 HIS B C 1 ATOM 3224 O O . HIS B 1 23 ? 8.451 5.192 46.906 1.00 48.92 ? 23 HIS B O 1 ATOM 3225 C CB . HIS B 1 23 ? 10.722 6.096 44.672 1.00 47.44 ? 23 HIS B CB 1 ATOM 3226 N N . ARG B 1 24 ? 8.305 4.145 44.923 1.00 39.82 ? 24 ARG B N 1 ATOM 3227 C CA . ARG B 1 24 ? 7.506 3.048 45.443 1.00 33.54 ? 24 ARG B CA 1 ATOM 3228 C C . ARG B 1 24 ? 8.289 1.742 45.466 1.00 26.20 ? 24 ARG B C 1 ATOM 3229 O O . ARG B 1 24 ? 9.334 1.602 44.827 1.00 29.20 ? 24 ARG B O 1 ATOM 3230 C CB . ARG B 1 24 ? 6.226 2.867 44.616 1.00 30.77 ? 24 ARG B CB 1 ATOM 3231 C CG . ARG B 1 24 ? 5.165 3.837 45.014 1.00 35.64 ? 24 ARG B CG 1 ATOM 3232 C CD . ARG B 1 24 ? 3.990 3.821 44.079 1.00 31.28 ? 24 ARG B CD 1 ATOM 3233 N NE . ARG B 1 24 ? 3.059 4.875 44.463 1.00 37.81 ? 24 ARG B NE 1 ATOM 3234 C CZ . ARG B 1 24 ? 3.068 6.106 43.966 1.00 35.38 ? 24 ARG B CZ 1 ATOM 3235 N NH1 . ARG B 1 24 ? 3.955 6.452 43.040 1.00 44.37 ? 24 ARG B NH1 1 ATOM 3236 N NH2 . ARG B 1 24 ? 2.181 6.993 44.393 1.00 37.76 ? 24 ARG B NH2 1 ATOM 3237 N N . LYS B 1 25 ? 7.757 0.790 46.222 1.00 24.86 ? 25 LYS B N 1 ATOM 3238 C CA . LYS B 1 25 ? 8.229 -0.584 46.168 1.00 25.65 ? 25 LYS B CA 1 ATOM 3239 C C . LYS B 1 25 ? 7.929 -1.170 44.791 1.00 25.11 ? 25 LYS B C 1 ATOM 3240 O O . LYS B 1 25 ? 7.060 -0.691 44.058 1.00 22.49 ? 25 LYS B O 1 ATOM 3241 C CB . LYS B 1 25 ? 7.559 -1.420 47.255 1.00 24.43 ? 25 LYS B CB 1 ATOM 3242 C CG . LYS B 1 25 ? 7.679 -0.849 48.681 1.00 32.63 ? 25 LYS B CG 1 ATOM 3243 C CD . LYS B 1 25 ? 8.952 -1.287 49.369 1.00 38.44 ? 25 LYS B CD 1 ATOM 3244 C CE . LYS B 1 25 ? 9.096 -0.672 50.768 1.00 41.84 ? 25 LYS B CE 1 ATOM 3245 N NZ . LYS B 1 25 ? 7.912 -0.906 51.640 1.00 48.49 ? 25 LYS B NZ 1 ATOM 3246 N N . LEU B 1 26 ? 8.668 -2.215 44.431 1.00 23.01 ? 26 LEU B N 1 ATOM 3247 C CA . LEU B 1 26 ? 8.517 -2.812 43.110 1.00 19.93 ? 26 LEU B CA 1 ATOM 3248 C C . LEU B 1 26 ? 8.562 -4.329 43.231 1.00 19.06 ? 26 LEU B C 1 ATOM 3249 O O . LEU B 1 26 ? 9.439 -4.877 43.906 1.00 18.79 ? 26 LEU B O 1 ATOM 3250 C CB . LEU B 1 26 ? 9.606 -2.316 42.144 1.00 19.41 ? 26 LEU B CB 1 ATOM 3251 C CG . LEU B 1 26 ? 9.585 -2.888 40.720 1.00 17.84 ? 26 LEU B CG 1 ATOM 3252 C CD1 . LEU B 1 26 ? 8.258 -2.592 40.030 1.00 19.58 ? 26 LEU B CD1 1 ATOM 3253 C CD2 . LEU B 1 26 ? 10.752 -2.346 39.883 1.00 18.23 ? 26 LEU B CD2 1 ATOM 3254 N N . LEU B 1 27 ? 7.590 -4.982 42.600 1.00 19.57 ? 27 LEU B N 1 ATOM 3255 C CA . LEU B 1 27 ? 7.530 -6.429 42.430 1.00 21.91 ? 27 LEU B CA 1 ATOM 3256 C C . LEU B 1 27 ? 7.692 -6.736 40.947 1.00 20.36 ? 27 LEU B C 1 ATOM 3257 O O . LEU B 1 27 ? 6.941 -6.216 40.124 1.00 18.80 ? 27 LEU B O 1 ATOM 3258 C CB . LEU B 1 27 ? 6.197 -6.984 42.937 1.00 16.95 ? 27 LEU B CB 1 ATOM 3259 C CG . LEU B 1 27 ? 5.966 -8.474 42.662 1.00 16.33 ? 27 LEU B CG 1 ATOM 3260 C CD1 . LEU B 1 27 ? 7.028 -9.340 43.357 1.00 18.72 ? 27 LEU B CD1 1 ATOM 3261 C CD2 . LEU B 1 27 ? 4.598 -8.868 43.133 1.00 20.19 ? 27 LEU B CD2 1 ATOM 3262 N N . VAL B 1 28 ? 8.690 -7.544 40.599 1.00 16.30 ? 28 VAL B N 1 ATOM 3263 C CA . VAL B 1 28 ? 8.957 -7.881 39.205 1.00 17.30 ? 28 VAL B CA 1 ATOM 3264 C C . VAL B 1 28 ? 8.759 -9.378 39.038 1.00 16.88 ? 28 VAL B C 1 ATOM 3265 O O . VAL B 1 28 ? 9.275 -10.164 39.842 1.00 17.34 ? 28 VAL B O 1 ATOM 3266 C CB . VAL B 1 28 ? 10.380 -7.465 38.783 1.00 21.61 ? 28 VAL B CB 1 ATOM 3267 C CG1 . VAL B 1 28 ? 10.704 -8.004 37.414 1.00 23.38 ? 28 VAL B CG1 1 ATOM 3268 C CG2 . VAL B 1 28 ? 10.510 -5.941 38.789 1.00 21.72 ? 28 VAL B CG2 1 ATOM 3269 N N . LEU B 1 29 ? 8.009 -9.769 38.001 1.00 16.79 ? 29 LEU B N 1 ATOM 3270 C CA . LEU B 1 29 ? 7.738 -11.173 37.700 1.00 17.43 ? 29 LEU B CA 1 ATOM 3271 C C . LEU B 1 29 ? 8.273 -11.498 36.311 1.00 18.69 ? 29 LEU B C 1 ATOM 3272 O O . LEU B 1 29 ? 7.865 -10.875 35.328 1.00 16.45 ? 29 LEU B O 1 ATOM 3273 C CB . LEU B 1 29 ? 6.241 -11.473 37.739 1.00 20.79 ? 29 LEU B CB 1 ATOM 3274 C CG . LEU B 1 29 ? 5.454 -11.053 38.970 1.00 24.97 ? 29 LEU B CG 1 ATOM 3275 C CD1 . LEU B 1 29 ? 4.002 -11.459 38.773 1.00 23.38 ? 29 LEU B CD1 1 ATOM 3276 C CD2 . LEU B 1 29 ? 6.059 -11.717 40.199 1.00 19.36 ? 29 LEU B CD2 1 ATOM 3277 N N . LEU B 1 30 ? 9.163 -12.488 36.230 1.00 15.63 ? 30 LEU B N 1 ATOM 3278 C CA . LEU B 1 30 ? 9.690 -12.982 34.964 1.00 16.94 ? 30 LEU B CA 1 ATOM 3279 C C . LEU B 1 30 ? 9.033 -14.334 34.679 1.00 20.59 ? 30 LEU B C 1 ATOM 3280 O O . LEU B 1 30 ? 9.250 -15.310 35.412 1.00 19.56 ? 30 LEU B O 1 ATOM 3281 C CB . LEU B 1 30 ? 11.215 -13.100 35.036 1.00 19.06 ? 30 LEU B CB 1 ATOM 3282 C CG . LEU B 1 30 ? 12.022 -13.780 33.924 1.00 24.99 ? 30 LEU B CG 1 ATOM 3283 C CD1 . LEU B 1 30 ? 11.588 -13.337 32.554 1.00 29.20 ? 30 LEU B CD1 1 ATOM 3284 C CD2 . LEU B 1 30 ? 13.514 -13.501 34.108 1.00 24.55 ? 30 LEU B CD2 1 ATOM 3285 N N . LEU B 1 31 ? 8.237 -14.389 33.613 1.00 17.72 ? 31 LEU B N 1 ATOM 3286 C CA . LEU B 1 31 ? 7.503 -15.589 33.223 1.00 17.36 ? 31 LEU B CA 1 ATOM 3287 C C . LEU B 1 31 ? 8.208 -16.177 32.006 1.00 23.59 ? 31 LEU B C 1 ATOM 3288 O O . LEU B 1 31 ? 8.028 -15.700 30.881 1.00 21.50 ? 31 LEU B O 1 ATOM 3289 C CB . LEU B 1 31 ? 6.049 -15.245 32.917 1.00 19.80 ? 31 LEU B CB 1 ATOM 3290 C CG . LEU B 1 31 ? 5.285 -14.530 34.031 1.00 21.30 ? 31 LEU B CG 1 ATOM 3291 C CD1 . LEU B 1 31 ? 3.833 -14.418 33.629 1.00 24.61 ? 31 LEU B CD1 1 ATOM 3292 C CD2 . LEU B 1 31 ? 5.405 -15.282 35.364 1.00 20.97 ? 31 LEU B CD2 1 ATOM 3293 N N . ASP B 1 32 ? 9.020 -17.204 32.233 1.00 21.02 ? 32 ASP B N 1 ATOM 3294 C CA . ASP B 1 32 ? 9.851 -17.746 31.167 1.00 18.29 ? 32 ASP B CA 1 ATOM 3295 C C . ASP B 1 32 ? 9.003 -18.296 30.017 1.00 17.79 ? 32 ASP B C 1 ATOM 3296 O O . ASP B 1 32 ? 8.008 -18.994 30.228 1.00 21.10 ? 32 ASP B O 1 ATOM 3297 C CB . ASP B 1 32 ? 10.750 -18.854 31.738 1.00 19.11 ? 32 ASP B CB 1 ATOM 3298 C CG . ASP B 1 32 ? 11.980 -19.089 30.890 1.00 24.35 ? 32 ASP B CG 1 ATOM 3299 O OD1 . ASP B 1 32 ? 11.826 -19.250 29.657 1.00 22.99 ? 32 ASP B OD1 1 ATOM 3300 O OD2 . ASP B 1 32 ? 13.101 -19.070 31.443 1.00 29.11 ? 32 ASP B OD2 1 ATOM 3301 N N . GLY B 1 33 ? 9.406 -17.985 28.786 1.00 24.94 ? 33 GLY B N 1 ATOM 3302 C CA . GLY B 1 33 ? 8.785 -18.610 27.627 1.00 20.92 ? 33 GLY B CA 1 ATOM 3303 C C . GLY B 1 33 ? 7.366 -18.166 27.330 1.00 25.72 ? 33 GLY B C 1 ATOM 3304 O O . GLY B 1 33 ? 6.631 -18.884 26.645 1.00 23.42 ? 33 GLY B O 1 ATOM 3305 N N . PHE B 1 34 ? 6.957 -17.005 27.841 1.00 21.19 ? 34 PHE B N 1 ATOM 3306 C CA . PHE B 1 34 ? 5.588 -16.510 27.705 1.00 21.58 ? 34 PHE B CA 1 ATOM 3307 C C . PHE B 1 34 ? 5.526 -15.715 26.404 1.00 22.78 ? 34 PHE B C 1 ATOM 3308 O O . PHE B 1 34 ? 5.995 -14.576 26.345 1.00 23.07 ? 34 PHE B O 1 ATOM 3309 C CB . PHE B 1 34 ? 5.232 -15.649 28.915 1.00 21.46 ? 34 PHE B CB 1 ATOM 3310 C CG . PHE B 1 34 ? 3.762 -15.412 29.111 1.00 23.86 ? 34 PHE B CG 1 ATOM 3311 C CD1 . PHE B 1 34 ? 2.993 -14.808 28.127 1.00 20.19 ? 34 PHE B CD1 1 ATOM 3312 C CD2 . PHE B 1 34 ? 3.165 -15.729 30.326 1.00 24.66 ? 34 PHE B CD2 1 ATOM 3313 C CE1 . PHE B 1 34 ? 1.646 -14.558 28.329 1.00 20.96 ? 34 PHE B CE1 1 ATOM 3314 C CE2 . PHE B 1 34 ? 1.828 -15.492 30.539 1.00 26.16 ? 34 PHE B CE2 1 ATOM 3315 C CZ . PHE B 1 34 ? 1.059 -14.897 29.540 1.00 25.86 ? 34 PHE B CZ 1 ATOM 3316 N N . ARG B 1 35 ? 4.944 -16.319 25.365 1.00 23.57 ? 35 ARG B N 1 ATOM 3317 C CA . ARG B 1 35 ? 4.859 -15.726 24.036 1.00 21.64 ? 35 ARG B CA 1 ATOM 3318 C C . ARG B 1 35 ? 3.770 -14.657 23.988 1.00 23.30 ? 35 ARG B C 1 ATOM 3319 O O . ARG B 1 35 ? 2.756 -14.746 24.682 1.00 23.76 ? 35 ARG B O 1 ATOM 3320 C CB . ARG B 1 35 ? 4.579 -16.820 22.992 1.00 21.73 ? 35 ARG B CB 1 ATOM 3321 C CG . ARG B 1 35 ? 4.702 -16.367 21.540 1.00 28.44 ? 35 ARG B CG 1 ATOM 3322 C CD . ARG B 1 35 ? 4.590 -17.549 20.558 1.00 24.71 ? 35 ARG B CD 1 ATOM 3323 N NE . ARG B 1 35 ? 3.227 -18.068 20.434 1.00 31.93 ? 35 ARG B NE 1 ATOM 3324 C CZ . ARG B 1 35 ? 2.884 -19.116 19.684 1.00 35.33 ? 35 ARG B CZ 1 ATOM 3325 N NH1 . ARG B 1 35 ? 3.801 -19.783 18.992 1.00 32.49 ? 35 ARG B NH1 1 ATOM 3326 N NH2 . ARG B 1 35 ? 1.621 -19.511 19.636 1.00 33.60 ? 35 ARG B NH2 1 ATOM 3327 N N . SER B 1 36 ? 3.991 -13.646 23.140 1.00 23.71 ? 36 SER B N 1 ATOM 3328 C CA . SER B 1 36 ? 3.118 -12.475 23.104 1.00 24.08 ? 36 SER B CA 1 ATOM 3329 C C . SER B 1 36 ? 1.666 -12.854 22.864 1.00 25.64 ? 36 SER B C 1 ATOM 3330 O O . SER B 1 36 ? 0.759 -12.316 23.516 1.00 26.01 ? 36 SER B O 1 ATOM 3331 C CB . SER B 1 36 ? 3.586 -11.505 22.018 1.00 24.75 ? 36 SER B CB 1 ATOM 3332 O OG . SER B 1 36 ? 2.649 -10.459 21.862 1.00 32.45 ? 36 SER B OG 1 ATOM 3333 N N . ASP B 1 37 ? 1.413 -13.752 21.916 1.00 25.19 ? 37 ASP B N 1 ATOM 3334 C CA . ASP B 1 37 ? 0.020 -14.007 21.583 1.00 28.39 ? 37 ASP B CA 1 ATOM 3335 C C . ASP B 1 37 ? -0.646 -14.960 22.560 1.00 27.83 ? 37 ASP B C 1 ATOM 3336 O O . ASP B 1 37 ? -1.834 -15.258 22.400 1.00 27.64 ? 37 ASP B O 1 ATOM 3337 C CB . ASP B 1 37 ? -0.117 -14.503 20.131 1.00 24.20 ? 37 ASP B CB 1 ATOM 3338 C CG . ASP B 1 37 ? 0.500 -15.876 19.890 1.00 31.73 ? 37 ASP B CG 1 ATOM 3339 O OD1 . ASP B 1 37 ? 0.944 -16.541 20.847 1.00 33.15 ? 37 ASP B OD1 1 ATOM 3340 O OD2 . ASP B 1 37 ? 0.523 -16.294 18.704 1.00 33.39 ? 37 ASP B OD2 1 ATOM 3341 N N . TYR B 1 38 ? 0.087 -15.439 23.572 1.00 25.16 ? 38 TYR B N 1 ATOM 3342 C CA . TYR B 1 38 ? -0.556 -16.155 24.669 1.00 23.72 ? 38 TYR B CA 1 ATOM 3343 C C . TYR B 1 38 ? -1.607 -15.314 25.374 1.00 25.41 ? 38 TYR B C 1 ATOM 3344 O O . TYR B 1 38 ? -2.505 -15.873 26.015 1.00 24.51 ? 38 TYR B O 1 ATOM 3345 C CB . TYR B 1 38 ? 0.476 -16.595 25.700 1.00 25.02 ? 38 TYR B CB 1 ATOM 3346 C CG . TYR B 1 38 ? 1.343 -17.745 25.283 1.00 27.94 ? 38 TYR B CG 1 ATOM 3347 C CD1 . TYR B 1 38 ? 1.163 -18.390 24.056 1.00 26.24 ? 38 TYR B CD1 1 ATOM 3348 C CD2 . TYR B 1 38 ? 2.340 -18.204 26.129 1.00 20.51 ? 38 TYR B CD2 1 ATOM 3349 C CE1 . TYR B 1 38 ? 1.971 -19.460 23.693 1.00 26.86 ? 38 TYR B CE1 1 ATOM 3350 C CE2 . TYR B 1 38 ? 3.147 -19.251 25.775 1.00 28.00 ? 38 TYR B CE2 1 ATOM 3351 C CZ . TYR B 1 38 ? 2.959 -19.887 24.562 1.00 29.83 ? 38 TYR B CZ 1 ATOM 3352 O OH . TYR B 1 38 ? 3.779 -20.952 24.239 1.00 29.06 ? 38 TYR B OH 1 ATOM 3353 N N . ILE B 1 39 ? -1.501 -13.986 25.297 1.00 23.77 ? 39 ILE B N 1 ATOM 3354 C CA . ILE B 1 39 ? -2.511 -13.096 25.856 1.00 25.20 ? 39 ILE B CA 1 ATOM 3355 C C . ILE B 1 39 ? -3.055 -12.192 24.755 1.00 21.40 ? 39 ILE B C 1 ATOM 3356 O O . ILE B 1 39 ? -3.294 -10.994 24.965 1.00 26.97 ? 39 ILE B O 1 ATOM 3357 C CB . ILE B 1 39 ? -1.946 -12.284 27.033 1.00 27.44 ? 39 ILE B CB 1 ATOM 3358 C CG1 . ILE B 1 39 ? -0.632 -11.611 26.625 1.00 24.42 ? 39 ILE B CG1 1 ATOM 3359 C CG2 . ILE B 1 39 ? -1.757 -13.210 28.256 1.00 23.81 ? 39 ILE B CG2 1 ATOM 3360 C CD1 . ILE B 1 39 ? -0.090 -10.615 27.649 1.00 21.82 ? 39 ILE B CD1 1 ATOM 3361 N N . SER B 1 40 ? -3.257 -12.765 23.573 1.00 25.93 ? 40 SER B N 1 ATOM 3362 C CA . SER B 1 40 ? -4.041 -12.104 22.537 1.00 25.52 ? 40 SER B CA 1 ATOM 3363 C C . SER B 1 40 ? -5.412 -11.717 23.076 1.00 30.28 ? 40 SER B C 1 ATOM 3364 O O . SER B 1 40 ? -5.863 -12.211 24.112 1.00 29.62 ? 40 SER B O 1 ATOM 3365 C CB . SER B 1 40 ? -4.233 -13.034 21.342 1.00 25.89 ? 40 SER B CB 1 ATOM 3366 O OG . SER B 1 40 ? -5.025 -14.149 21.736 1.00 27.77 ? 40 SER B OG 1 ATOM 3367 N N . GLU B 1 41 ? -6.105 -10.853 22.327 1.00 29.36 ? 41 GLU B N 1 ATOM 3368 C CA . GLU B 1 41 ? -7.461 -10.483 22.711 1.00 35.59 ? 41 GLU B CA 1 ATOM 3369 C C . GLU B 1 41 ? -8.351 -11.714 22.860 1.00 31.30 ? 41 GLU B C 1 ATOM 3370 O O . GLU B 1 41 ? -9.128 -11.817 23.821 1.00 28.31 ? 41 GLU B O 1 ATOM 3371 C CB . GLU B 1 41 ? -8.039 -9.514 21.683 1.00 31.61 ? 41 GLU B CB 1 ATOM 3372 C CG . GLU B 1 41 ? -8.771 -8.327 22.275 1.00 49.29 ? 41 GLU B CG 1 ATOM 3373 C CD . GLU B 1 41 ? -7.919 -7.516 23.242 1.00 54.90 ? 41 GLU B CD 1 ATOM 3374 O OE1 . GLU B 1 41 ? -8.498 -6.929 24.181 1.00 57.57 ? 41 GLU B OE1 1 ATOM 3375 O OE2 . GLU B 1 41 ? -6.676 -7.461 23.073 1.00 56.02 ? 41 GLU B OE2 1 ATOM 3376 N N . ASP B 1 42 ? -8.227 -12.671 21.934 1.00 26.10 ? 42 ASP B N 1 ATOM 3377 C CA . ASP B 1 42 ? -9.019 -13.896 22.006 1.00 29.58 ? 42 ASP B CA 1 ATOM 3378 C C . ASP B 1 42 ? -8.708 -14.679 23.273 1.00 34.60 ? 42 ASP B C 1 ATOM 3379 O O . ASP B 1 42 ? -9.614 -15.172 23.955 1.00 32.85 ? 42 ASP B O 1 ATOM 3380 C CB . ASP B 1 42 ? -8.746 -14.779 20.790 1.00 32.66 ? 42 ASP B CB 1 ATOM 3381 C CG . ASP B 1 42 ? -9.315 -14.212 19.505 1.00 40.99 ? 42 ASP B CG 1 ATOM 3382 O OD1 . ASP B 1 42 ? -10.120 -13.253 19.561 1.00 37.01 ? 42 ASP B OD1 1 ATOM 3383 O OD2 . ASP B 1 42 ? -8.950 -14.743 18.436 1.00 37.07 ? 42 ASP B OD2 1 ATOM 3384 N N . ALA B 1 43 ? -7.421 -14.836 23.583 1.00 30.34 ? 43 ALA B N 1 ATOM 3385 C CA . ALA B 1 43 ? -7.036 -15.621 24.748 1.00 30.51 ? 43 ALA B CA 1 ATOM 3386 C C . ALA B 1 43 ? -7.465 -14.941 26.040 1.00 30.07 ? 43 ALA B C 1 ATOM 3387 O O . ALA B 1 43 ? -7.784 -15.614 27.025 1.00 34.77 ? 43 ALA B O 1 ATOM 3388 C CB . ALA B 1 43 ? -5.523 -15.858 24.742 1.00 33.23 ? 43 ALA B CB 1 ATOM 3389 N N . LEU B 1 44 ? -7.464 -13.605 26.064 1.00 25.83 ? 44 LEU B N 1 ATOM 3390 C CA . LEU B 1 44 ? -7.762 -12.902 27.306 1.00 28.27 ? 44 LEU B CA 1 ATOM 3391 C C . LEU B 1 44 ? -9.191 -13.139 27.769 1.00 35.78 ? 44 LEU B C 1 ATOM 3392 O O . LEU B 1 44 ? -9.487 -12.941 28.953 1.00 32.64 ? 44 LEU B O 1 ATOM 3393 C CB . LEU B 1 44 ? -7.504 -11.406 27.140 1.00 32.82 ? 44 LEU B CB 1 ATOM 3394 C CG . LEU B 1 44 ? -6.040 -10.964 27.243 1.00 30.39 ? 44 LEU B CG 1 ATOM 3395 C CD1 . LEU B 1 44 ? -5.913 -9.473 26.972 1.00 29.34 ? 44 LEU B CD1 1 ATOM 3396 C CD2 . LEU B 1 44 ? -5.471 -11.314 28.608 1.00 28.47 ? 44 LEU B CD2 1 ATOM 3397 N N . ALA B 1 45 ? -10.074 -13.577 26.863 1.00 42.86 ? 45 ALA B N 1 ATOM 3398 C CA . ALA B 1 45 ? -11.468 -13.833 27.217 1.00 38.39 ? 45 ALA B CA 1 ATOM 3399 C C . ALA B 1 45 ? -11.605 -14.893 28.307 1.00 35.94 ? 45 ALA B C 1 ATOM 3400 O O . ALA B 1 45 ? -12.593 -14.888 29.046 1.00 46.46 ? 45 ALA B O 1 ATOM 3401 C CB . ALA B 1 45 ? -12.248 -14.253 25.970 1.00 35.92 ? 45 ALA B CB 1 ATOM 3402 N N . SER B 1 46 ? -10.639 -15.803 28.435 1.00 30.79 ? 46 SER B N 1 ATOM 3403 C CA . SER B 1 46 ? -10.688 -16.818 29.486 1.00 36.26 ? 46 SER B CA 1 ATOM 3404 C C . SER B 1 46 ? -9.510 -16.717 30.454 1.00 35.91 ? 46 SER B C 1 ATOM 3405 O O . SER B 1 46 ? -9.130 -17.717 31.076 1.00 34.13 ? 46 SER B O 1 ATOM 3406 C CB . SER B 1 46 ? -10.769 -18.223 28.880 1.00 39.35 ? 46 SER B CB 1 ATOM 3407 O OG . SER B 1 46 ? -9.711 -18.480 27.972 1.00 51.37 ? 46 SER B OG 1 ATOM 3408 N N . LEU B 1 47 ? -8.928 -15.527 30.607 1.00 32.12 ? 47 LEU B N 1 ATOM 3409 C CA . LEU B 1 47 ? -7.782 -15.302 31.491 1.00 32.03 ? 47 LEU B CA 1 ATOM 3410 C C . LEU B 1 47 ? -8.097 -14.115 32.394 1.00 28.86 ? 47 LEU B C 1 ATOM 3411 O O . LEU B 1 47 ? -7.606 -12.997 32.175 1.00 29.82 ? 47 LEU B O 1 ATOM 3412 C CB . LEU B 1 47 ? -6.503 -15.072 30.683 1.00 28.56 ? 47 LEU B CB 1 ATOM 3413 C CG . LEU B 1 47 ? -5.983 -16.237 29.825 1.00 29.31 ? 47 LEU B CG 1 ATOM 3414 C CD1 . LEU B 1 47 ? -4.818 -15.779 28.951 1.00 28.18 ? 47 LEU B CD1 1 ATOM 3415 C CD2 . LEU B 1 47 ? -5.560 -17.434 30.690 1.00 29.31 ? 47 LEU B CD2 1 ATOM 3416 N N . PRO B 1 48 ? -8.900 -14.328 33.441 1.00 33.72 ? 48 PRO B N 1 ATOM 3417 C CA . PRO B 1 48 ? -9.362 -13.186 34.254 1.00 30.75 ? 48 PRO B CA 1 ATOM 3418 C C . PRO B 1 48 ? -8.254 -12.450 34.988 1.00 24.94 ? 48 PRO B C 1 ATOM 3419 O O . PRO B 1 48 ? -8.367 -11.240 35.210 1.00 28.20 ? 48 PRO B O 1 ATOM 3420 C CB . PRO B 1 48 ? -10.343 -13.840 35.233 1.00 36.02 ? 48 PRO B CB 1 ATOM 3421 C CG . PRO B 1 48 ? -9.858 -15.251 35.346 1.00 36.42 ? 48 PRO B CG 1 ATOM 3422 C CD . PRO B 1 48 ? -9.386 -15.615 33.963 1.00 36.02 ? 48 PRO B CD 1 ATOM 3423 N N . GLY B 1 49 ? -7.199 -13.145 35.401 1.00 29.85 ? 49 GLY B N 1 ATOM 3424 C CA . GLY B 1 49 ? -6.098 -12.474 36.060 1.00 30.46 ? 49 GLY B CA 1 ATOM 3425 C C . GLY B 1 49 ? -5.398 -11.496 35.139 1.00 26.33 ? 49 GLY B C 1 ATOM 3426 O O . GLY B 1 49 ? -5.219 -10.325 35.489 1.00 26.67 ? 49 GLY B O 1 ATOM 3427 N N . PHE B 1 50 ? -4.990 -11.965 33.955 1.00 24.57 ? 50 PHE B N 1 ATOM 3428 C CA . PHE B 1 50 ? -4.348 -11.065 33.001 1.00 23.70 ? 50 PHE B CA 1 ATOM 3429 C C . PHE B 1 50 ? -5.317 -10.002 32.526 1.00 25.76 ? 50 PHE B C 1 ATOM 3430 O O . PHE B 1 50 ? -4.927 -8.856 32.286 1.00 29.13 ? 50 PHE B O 1 ATOM 3431 C CB . PHE B 1 50 ? -3.790 -11.846 31.817 1.00 22.84 ? 50 PHE B CB 1 ATOM 3432 C CG . PHE B 1 50 ? -2.496 -12.541 32.118 1.00 26.29 ? 50 PHE B CG 1 ATOM 3433 C CD1 . PHE B 1 50 ? -1.300 -11.835 32.098 1.00 29.12 ? 50 PHE B CD1 1 ATOM 3434 C CD2 . PHE B 1 50 ? -2.473 -13.898 32.401 1.00 26.07 ? 50 PHE B CD2 1 ATOM 3435 C CE1 . PHE B 1 50 ? -0.098 -12.470 32.378 1.00 27.30 ? 50 PHE B CE1 1 ATOM 3436 C CE2 . PHE B 1 50 ? -1.283 -14.535 32.680 1.00 25.25 ? 50 PHE B CE2 1 ATOM 3437 C CZ . PHE B 1 50 ? -0.093 -13.819 32.666 1.00 24.44 ? 50 PHE B CZ 1 ATOM 3438 N N . ARG B 1 51 ? -6.593 -10.359 32.401 1.00 28.95 ? 51 ARG B N 1 ATOM 3439 C CA . ARG B 1 51 ? -7.561 -9.387 31.929 1.00 27.87 ? 51 ARG B CA 1 ATOM 3440 C C . ARG B 1 51 ? -7.653 -8.207 32.881 1.00 25.27 ? 51 ARG B C 1 ATOM 3441 O O . ARG B 1 51 ? -7.741 -7.054 32.443 1.00 33.78 ? 51 ARG B O 1 ATOM 3442 C CB . ARG B 1 51 ? -8.921 -10.058 31.745 1.00 33.86 ? 51 ARG B CB 1 ATOM 3443 C CG . ARG B 1 51 ? -9.895 -9.235 30.933 1.00 39.14 ? 51 ARG B CG 1 ATOM 3444 C CD . ARG B 1 51 ? -11.058 -10.080 30.418 1.00 35.28 ? 51 ARG B CD 1 ATOM 3445 N NE . ARG B 1 51 ? -11.897 -10.597 31.495 1.00 37.26 ? 51 ARG B NE 1 ATOM 3446 C CZ . ARG B 1 51 ? -12.049 -11.885 31.778 1.00 33.73 ? 51 ARG B CZ 1 ATOM 3447 N NH1 . ARG B 1 51 ? -11.419 -12.807 31.062 1.00 37.12 ? 51 ARG B NH1 1 ATOM 3448 N NH2 . ARG B 1 51 ? -12.836 -12.252 32.780 1.00 41.32 ? 51 ARG B NH2 1 ATOM 3449 N N . GLU B 1 52 ? -7.617 -8.474 34.189 1.00 27.18 ? 52 GLU B N 1 ATOM 3450 C CA . GLU B 1 52 ? -7.684 -7.396 35.165 1.00 28.82 ? 52 GLU B CA 1 ATOM 3451 C C . GLU B 1 52 ? -6.449 -6.511 35.100 1.00 26.96 ? 52 GLU B C 1 ATOM 3452 O O . GLU B 1 52 ? -6.551 -5.287 35.215 1.00 27.80 ? 52 GLU B O 1 ATOM 3453 C CB . GLU B 1 52 ? -7.855 -7.955 36.578 1.00 31.49 ? 52 GLU B CB 1 ATOM 3454 C CG . GLU B 1 52 ? -8.046 -6.833 37.576 1.00 37.38 ? 52 GLU B CG 1 ATOM 3455 C CD . GLU B 1 52 ? -8.405 -7.294 38.968 1.00 42.40 ? 52 GLU B CD 1 ATOM 3456 O OE1 . GLU B 1 52 ? -8.366 -8.516 39.238 1.00 41.88 ? 52 GLU B OE1 1 ATOM 3457 O OE2 . GLU B 1 52 ? -8.724 -6.410 39.798 1.00 43.67 ? 52 GLU B OE2 1 ATOM 3458 N N . ILE B 1 53 ? -5.269 -7.111 34.929 1.00 28.84 ? 53 ILE B N 1 ATOM 3459 C CA . ILE B 1 53 ? -4.061 -6.307 34.771 1.00 28.09 ? 53 ILE B CA 1 ATOM 3460 C C . ILE B 1 53 ? -4.155 -5.448 33.518 1.00 23.59 ? 53 ILE B C 1 ATOM 3461 O O . ILE B 1 53 ? -3.832 -4.251 33.538 1.00 25.35 ? 53 ILE B O 1 ATOM 3462 C CB . ILE B 1 53 ? -2.815 -7.214 34.756 1.00 26.72 ? 53 ILE B CB 1 ATOM 3463 C CG1 . ILE B 1 53 ? -2.699 -7.948 36.089 1.00 26.98 ? 53 ILE B CG1 1 ATOM 3464 C CG2 . ILE B 1 53 ? -1.575 -6.389 34.501 1.00 23.69 ? 53 ILE B CG2 1 ATOM 3465 C CD1 . ILE B 1 53 ? -1.623 -9.021 36.118 1.00 26.94 ? 53 ILE B CD1 1 ATOM 3466 N N . VAL B 1 54 ? -4.620 -6.033 32.409 1.00 25.52 ? 54 VAL B N 1 ATOM 3467 C CA . VAL B 1 54 ? -4.777 -5.251 31.186 1.00 27.66 ? 54 VAL B CA 1 ATOM 3468 C C . VAL B 1 54 ? -5.796 -4.137 31.400 1.00 30.23 ? 54 VAL B C 1 ATOM 3469 O O . VAL B 1 54 ? -5.571 -2.992 30.993 1.00 27.51 ? 54 VAL B O 1 ATOM 3470 C CB . VAL B 1 54 ? -5.168 -6.159 30.004 1.00 28.09 ? 54 VAL B CB 1 ATOM 3471 C CG1 . VAL B 1 54 ? -5.655 -5.328 28.826 1.00 30.47 ? 54 VAL B CG1 1 ATOM 3472 C CG2 . VAL B 1 54 ? -3.991 -7.045 29.593 1.00 25.80 ? 54 VAL B CG2 1 ATOM 3473 N N . ASN B 1 55 ? -6.908 -4.442 32.083 1.00 33.53 ? 55 ASN B N 1 ATOM 3474 C CA . ASN B 1 55 ? -7.979 -3.456 32.238 1.00 31.44 ? 55 ASN B CA 1 ATOM 3475 C C . ASN B 1 55 ? -7.592 -2.326 33.181 1.00 36.32 ? 55 ASN B C 1 ATOM 3476 O O . ASN B 1 55 ? -8.088 -1.203 33.029 1.00 32.83 ? 55 ASN B O 1 ATOM 3477 C CB . ASN B 1 55 ? -9.257 -4.118 32.753 1.00 34.73 ? 55 ASN B CB 1 ATOM 3478 C CG . ASN B 1 55 ? -9.988 -4.886 31.683 1.00 36.94 ? 55 ASN B CG 1 ATOM 3479 O OD1 . ASN B 1 55 ? -9.858 -4.595 30.493 1.00 45.24 ? 55 ASN B OD1 1 ATOM 3480 N ND2 . ASN B 1 55 ? -10.770 -5.874 32.099 1.00 37.74 ? 55 ASN B ND2 1 ATOM 3481 N N . ARG B 1 56 ? -6.728 -2.595 34.161 1.00 29.67 ? 56 ARG B N 1 ATOM 3482 C CA . ARG B 1 56 ? -6.365 -1.596 35.157 1.00 31.73 ? 56 ARG B CA 1 ATOM 3483 C C . ARG B 1 56 ? -4.910 -1.142 35.052 1.00 31.17 ? 56 ARG B C 1 ATOM 3484 O O . ARG B 1 56 ? -4.455 -0.365 35.898 1.00 28.91 ? 56 ARG B O 1 ATOM 3485 C CB . ARG B 1 56 ? -6.664 -2.134 36.560 1.00 31.52 ? 56 ARG B CB 1 ATOM 3486 C CG . ARG B 1 56 ? -8.159 -2.370 36.809 1.00 35.41 ? 56 ARG B CG 1 ATOM 3487 C CD . ARG B 1 56 ? -8.432 -2.995 38.170 1.00 37.90 ? 56 ARG B CD 1 ATOM 3488 N NE . ARG B 1 56 ? -7.901 -2.179 39.256 1.00 55.50 ? 56 ARG B NE 1 ATOM 3489 C CZ . ARG B 1 56 ? -6.942 -2.567 40.093 1.00 54.08 ? 56 ARG B CZ 1 ATOM 3490 N NH1 . ARG B 1 56 ? -6.409 -3.777 39.987 1.00 46.72 ? 56 ARG B NH1 1 ATOM 3491 N NH2 . ARG B 1 56 ? -6.525 -1.747 41.049 1.00 60.13 ? 56 ARG B NH2 1 ATOM 3492 N N . GLY B 1 57 ? -4.178 -1.583 34.030 1.00 28.96 ? 57 GLY B N 1 ATOM 3493 C CA . GLY B 1 57 ? -2.777 -1.217 33.891 1.00 28.36 ? 57 GLY B CA 1 ATOM 3494 C C . GLY B 1 57 ? -2.305 -1.070 32.457 1.00 27.26 ? 57 GLY B C 1 ATOM 3495 O O . GLY B 1 57 ? -3.076 -0.683 31.574 1.00 30.71 ? 57 GLY B O 1 ATOM 3496 N N . VAL B 1 58 ? -1.031 -1.378 32.217 1.00 25.51 ? 58 VAL B N 1 ATOM 3497 C CA . VAL B 1 58 ? -0.372 -1.197 30.925 1.00 22.59 ? 58 VAL B CA 1 ATOM 3498 C C . VAL B 1 58 ? -0.093 -2.558 30.303 1.00 27.17 ? 58 VAL B C 1 ATOM 3499 O O . VAL B 1 58 ? 0.374 -3.478 30.984 1.00 22.38 ? 58 VAL B O 1 ATOM 3500 C CB . VAL B 1 58 ? 0.945 -0.412 31.103 1.00 26.65 ? 58 VAL B CB 1 ATOM 3501 C CG1 . VAL B 1 58 ? 1.796 -0.459 29.826 1.00 27.28 ? 58 VAL B CG1 1 ATOM 3502 C CG2 . VAL B 1 58 ? 0.669 1.034 31.559 1.00 23.29 ? 58 VAL B CG2 1 ATOM 3503 N N . LYS B 1 59 ? -0.338 -2.680 28.999 1.00 24.78 ? 59 LYS B N 1 ATOM 3504 C CA . LYS B 1 59 ? 0.113 -3.844 28.247 1.00 25.17 ? 59 LYS B CA 1 ATOM 3505 C C . LYS B 1 59 ? 0.731 -3.387 26.933 1.00 30.26 ? 59 LYS B C 1 ATOM 3506 O O . LYS B 1 59 ? 0.099 -2.649 26.170 1.00 24.48 ? 59 LYS B O 1 ATOM 3507 C CB . LYS B 1 59 ? -1.040 -4.816 27.964 1.00 27.33 ? 59 LYS B CB 1 ATOM 3508 C CG . LYS B 1 59 ? -0.616 -6.026 27.145 1.00 24.12 ? 59 LYS B CG 1 ATOM 3509 C CD . LYS B 1 59 ? -1.799 -6.777 26.569 1.00 27.31 ? 59 LYS B CD 1 ATOM 3510 C CE . LYS B 1 59 ? -1.334 -7.936 25.684 1.00 33.59 ? 59 LYS B CE 1 ATOM 3511 N NZ . LYS B 1 59 ? -0.662 -7.463 24.426 1.00 31.13 ? 59 LYS B NZ 1 ATOM 3512 N N . VAL B 1 60 ? 1.956 -3.832 26.648 1.00 24.44 ? 60 VAL B N 1 ATOM 3513 C CA . VAL B 1 60 ? 2.516 -3.556 25.331 1.00 20.72 ? 60 VAL B CA 1 ATOM 3514 C C . VAL B 1 60 ? 2.019 -4.604 24.351 1.00 25.31 ? 60 VAL B C 1 ATOM 3515 O O . VAL B 1 60 ? 1.697 -5.739 24.726 1.00 23.13 ? 60 VAL B O 1 ATOM 3516 C CB . VAL B 1 60 ? 4.056 -3.495 25.360 1.00 27.11 ? 60 VAL B CB 1 ATOM 3517 C CG1 . VAL B 1 60 ? 4.524 -2.491 26.411 1.00 27.62 ? 60 VAL B CG1 1 ATOM 3518 C CG2 . VAL B 1 60 ? 4.630 -4.862 25.581 1.00 23.74 ? 60 VAL B CG2 1 ATOM 3519 N N . ASP B 1 61 ? 1.921 -4.206 23.076 1.00 24.74 ? 61 ASP B N 1 ATOM 3520 C CA . ASP B 1 61 ? 1.506 -5.149 22.043 1.00 26.05 ? 61 ASP B CA 1 ATOM 3521 C C . ASP B 1 61 ? 2.383 -6.393 22.051 1.00 23.12 ? 61 ASP B C 1 ATOM 3522 O O . ASP B 1 61 ? 1.884 -7.514 21.911 1.00 24.63 ? 61 ASP B O 1 ATOM 3523 C CB . ASP B 1 61 ? 1.545 -4.484 20.667 1.00 29.51 ? 61 ASP B CB 1 ATOM 3524 C CG . ASP B 1 61 ? 0.406 -3.486 20.462 1.00 34.86 ? 61 ASP B CG 1 ATOM 3525 O OD1 . ASP B 1 61 ? -0.459 -3.343 21.361 1.00 39.24 ? 61 ASP B OD1 1 ATOM 3526 O OD2 . ASP B 1 61 ? 0.373 -2.861 19.388 1.00 42.71 ? 61 ASP B OD2 1 ATOM 3527 N N . TYR B 1 62 ? 3.693 -6.208 22.185 1.00 24.00 ? 62 TYR B N 1 ATOM 3528 C CA . TYR B 1 62 ? 4.611 -7.322 22.400 1.00 23.38 ? 62 TYR B CA 1 ATOM 3529 C C . TYR B 1 62 ? 5.950 -6.759 22.831 1.00 24.22 ? 62 TYR B C 1 ATOM 3530 O O . TYR B 1 62 ? 6.220 -5.562 22.698 1.00 20.62 ? 62 TYR B O 1 ATOM 3531 C CB . TYR B 1 62 ? 4.784 -8.213 21.165 1.00 19.47 ? 62 TYR B CB 1 ATOM 3532 C CG . TYR B 1 62 ? 5.085 -7.492 19.871 1.00 25.13 ? 62 TYR B CG 1 ATOM 3533 C CD1 . TYR B 1 62 ? 4.052 -7.052 19.057 1.00 26.25 ? 62 TYR B CD1 1 ATOM 3534 C CD2 . TYR B 1 62 ? 6.398 -7.270 19.447 1.00 26.66 ? 62 TYR B CD2 1 ATOM 3535 C CE1 . TYR B 1 62 ? 4.305 -6.404 17.848 1.00 27.67 ? 62 TYR B CE1 1 ATOM 3536 C CE2 . TYR B 1 62 ? 6.661 -6.604 18.227 1.00 26.66 ? 62 TYR B CE2 1 ATOM 3537 C CZ . TYR B 1 62 ? 5.601 -6.184 17.439 1.00 28.96 ? 62 TYR B CZ 1 ATOM 3538 O OH . TYR B 1 62 ? 5.833 -5.527 16.239 1.00 28.24 ? 62 TYR B OH 1 ATOM 3539 N N . LEU B 1 63 ? 6.778 -7.654 23.371 1.00 20.74 ? 63 LEU B N 1 ATOM 3540 C CA . LEU B 1 63 ? 8.158 -7.382 23.753 1.00 22.31 ? 63 LEU B CA 1 ATOM 3541 C C . LEU B 1 63 ? 9.056 -8.121 22.767 1.00 19.00 ? 63 LEU B C 1 ATOM 3542 O O . LEU B 1 63 ? 8.932 -9.338 22.609 1.00 24.88 ? 63 LEU B O 1 ATOM 3543 C CB . LEU B 1 63 ? 8.410 -7.850 25.196 1.00 20.34 ? 63 LEU B CB 1 ATOM 3544 C CG . LEU B 1 63 ? 9.825 -7.652 25.751 1.00 26.95 ? 63 LEU B CG 1 ATOM 3545 C CD1 . LEU B 1 63 ? 10.144 -6.192 25.693 1.00 24.38 ? 63 LEU B CD1 1 ATOM 3546 C CD2 . LEU B 1 63 ? 9.916 -8.141 27.196 1.00 29.11 ? 63 LEU B CD2 1 ATOM 3547 N N . THR B 1 64 ? 9.942 -7.399 22.089 1.00 22.07 ? 64 THR B N 1 ATOM 3548 C CA . THR B 1 64 ? 10.884 -8.056 21.187 1.00 18.83 ? 64 THR B CA 1 ATOM 3549 C C . THR B 1 64 ? 12.152 -8.410 21.948 1.00 22.42 ? 64 THR B C 1 ATOM 3550 O O . THR B 1 64 ? 12.808 -7.505 22.486 1.00 20.92 ? 64 THR B O 1 ATOM 3551 C CB . THR B 1 64 ? 11.222 -7.157 20.011 1.00 26.56 ? 64 THR B CB 1 ATOM 3552 O OG1 . THR B 1 64 ? 10.019 -6.873 19.297 1.00 24.38 ? 64 THR B OG1 1 ATOM 3553 C CG2 . THR B 1 64 ? 12.199 -7.853 19.068 1.00 24.88 ? 64 THR B CG2 1 ATOM 3554 N N . PRO B 1 65 ? 12.523 -9.683 22.044 1.00 20.18 ? 65 PRO B N 1 ATOM 3555 C CA . PRO B 1 65 ? 13.693 -10.052 22.843 1.00 21.42 ? 65 PRO B CA 1 ATOM 3556 C C . PRO B 1 65 ? 14.987 -9.725 22.101 1.00 25.52 ? 65 PRO B C 1 ATOM 3557 O O . PRO B 1 65 ? 14.984 -9.340 20.936 1.00 22.28 ? 65 PRO B O 1 ATOM 3558 C CB . PRO B 1 65 ? 13.507 -11.554 23.036 1.00 21.80 ? 65 PRO B CB 1 ATOM 3559 C CG . PRO B 1 65 ? 12.919 -11.986 21.758 1.00 20.26 ? 65 PRO B CG 1 ATOM 3560 C CD . PRO B 1 65 ? 11.932 -10.865 21.388 1.00 20.01 ? 65 PRO B CD 1 ATOM 3561 N N . ASP B 1 66 ? 16.102 -9.837 22.825 1.00 25.88 ? 66 ASP B N 1 ATOM 3562 C CA . ASP B 1 66 ? 17.429 -9.786 22.216 1.00 24.46 ? 66 ASP B CA 1 ATOM 3563 C C . ASP B 1 66 ? 17.724 -11.093 21.476 1.00 24.85 ? 66 ASP B C 1 ATOM 3564 O O . ASP B 1 66 ? 17.120 -12.132 21.746 1.00 24.14 ? 66 ASP B O 1 ATOM 3565 C CB . ASP B 1 66 ? 18.501 -9.559 23.286 1.00 27.56 ? 66 ASP B CB 1 ATOM 3566 C CG . ASP B 1 66 ? 19.158 -8.190 23.207 1.00 29.20 ? 66 ASP B CG 1 ATOM 3567 O OD1 . ASP B 1 66 ? 18.757 -7.345 22.381 1.00 32.60 ? 66 ASP B OD1 1 ATOM 3568 O OD2 . ASP B 1 66 ? 20.092 -7.951 24.011 1.00 33.63 ? 66 ASP B OD2 1 ATOM 3569 N N . PHE B 1 67 ? 18.649 -11.026 20.515 1.00 25.13 ? 67 PHE B N 1 ATOM 3570 C CA . PHE B 1 67 ? 19.209 -12.239 19.919 1.00 26.01 ? 67 PHE B CA 1 ATOM 3571 C C . PHE B 1 67 ? 20.395 -12.695 20.770 1.00 20.31 ? 67 PHE B C 1 ATOM 3572 O O . PHE B 1 67 ? 21.197 -11.869 21.178 1.00 24.85 ? 67 PHE B O 1 ATOM 3573 C CB . PHE B 1 67 ? 19.669 -12.019 18.465 1.00 26.67 ? 67 PHE B CB 1 ATOM 3574 C CG . PHE B 1 67 ? 20.360 -13.223 17.880 1.00 27.00 ? 67 PHE B CG 1 ATOM 3575 C CD1 . PHE B 1 67 ? 19.635 -14.203 17.234 1.00 29.57 ? 67 PHE B CD1 1 ATOM 3576 C CD2 . PHE B 1 67 ? 21.733 -13.400 18.044 1.00 29.86 ? 67 PHE B CD2 1 ATOM 3577 C CE1 . PHE B 1 67 ? 20.273 -15.332 16.728 1.00 30.31 ? 67 PHE B CE1 1 ATOM 3578 C CE2 . PHE B 1 67 ? 22.368 -14.518 17.551 1.00 25.53 ? 67 PHE B CE2 1 ATOM 3579 C CZ . PHE B 1 67 ? 21.644 -15.485 16.891 1.00 25.59 ? 67 PHE B CZ 1 ATOM 3580 N N . PRO B 1 68 ? 20.512 -14.003 21.045 1.00 23.16 ? 68 PRO B N 1 ATOM 3581 C CA . PRO B 1 68 ? 19.596 -15.087 20.687 1.00 25.98 ? 68 PRO B CA 1 ATOM 3582 C C . PRO B 1 68 ? 18.417 -15.104 21.643 1.00 29.34 ? 68 PRO B C 1 ATOM 3583 O O . PRO B 1 68 ? 18.564 -14.671 22.794 1.00 27.54 ? 68 PRO B O 1 ATOM 3584 C CB . PRO B 1 68 ? 20.456 -16.342 20.847 1.00 30.31 ? 68 PRO B CB 1 ATOM 3585 C CG . PRO B 1 68 ? 21.396 -15.980 21.959 1.00 28.34 ? 68 PRO B CG 1 ATOM 3586 C CD . PRO B 1 68 ? 21.702 -14.508 21.759 1.00 26.14 ? 68 PRO B CD 1 ATOM 3587 N N . SER B 1 69 ? 17.266 -15.598 21.192 1.00 25.43 ? 69 SER B N 1 ATOM 3588 C CA . SER B 1 69 ? 16.056 -15.557 22.011 1.00 27.62 ? 69 SER B CA 1 ATOM 3589 C C . SER B 1 69 ? 16.053 -16.727 23.000 1.00 22.34 ? 69 SER B C 1 ATOM 3590 O O . SER B 1 69 ? 15.184 -17.597 23.003 1.00 24.25 ? 69 SER B O 1 ATOM 3591 C CB . SER B 1 69 ? 14.818 -15.525 21.121 1.00 28.67 ? 69 SER B CB 1 ATOM 3592 O OG . SER B 1 69 ? 14.867 -16.498 20.092 1.00 27.07 ? 69 SER B OG 1 ATOM 3593 N N . LEU B 1 70 ? 17.069 -16.702 23.860 1.00 25.78 ? 70 LEU B N 1 ATOM 3594 C CA . LEU B 1 70 ? 17.364 -17.688 24.893 1.00 25.72 ? 70 LEU B CA 1 ATOM 3595 C C . LEU B 1 70 ? 17.293 -17.031 26.268 1.00 23.91 ? 70 LEU B C 1 ATOM 3596 O O . LEU B 1 70 ? 17.347 -15.806 26.390 1.00 25.36 ? 70 LEU B O 1 ATOM 3597 C CB . LEU B 1 70 ? 18.764 -18.275 24.688 1.00 22.88 ? 70 LEU B CB 1 ATOM 3598 C CG . LEU B 1 70 ? 19.006 -19.063 23.405 1.00 24.25 ? 70 LEU B CG 1 ATOM 3599 C CD1 . LEU B 1 70 ? 20.479 -19.464 23.340 1.00 31.44 ? 70 LEU B CD1 1 ATOM 3600 C CD2 . LEU B 1 70 ? 18.113 -20.284 23.398 1.00 25.29 ? 70 LEU B CD2 1 ATOM 3601 N N . SER B 1 71 ? 17.240 -17.867 27.313 1.00 24.52 ? 71 SER B N 1 ATOM 3602 C CA . SER B 1 71 ? 17.072 -17.405 28.693 1.00 22.02 ? 71 SER B CA 1 ATOM 3603 C C . SER B 1 71 ? 18.178 -16.521 29.245 1.00 21.42 ? 71 SER B C 1 ATOM 3604 O O . SER B 1 71 ? 17.968 -15.323 29.426 1.00 20.64 ? 71 SER B O 1 ATOM 3605 C CB . SER B 1 71 ? 16.920 -18.594 29.632 1.00 25.45 ? 71 SER B CB 1 ATOM 3606 O OG . SER B 1 71 ? 15.590 -19.051 29.587 1.00 36.49 ? 71 SER B OG 1 ATOM 3607 N N . TYR B 1 72 ? 19.324 -17.098 29.616 1.00 21.95 ? 72 TYR B N 1 ATOM 3608 C CA . TYR B 1 72 ? 20.348 -16.285 30.263 1.00 18.56 ? 72 TYR B CA 1 ATOM 3609 C C . TYR B 1 72 ? 20.705 -15.025 29.495 1.00 22.26 ? 72 TYR B C 1 ATOM 3610 O O . TYR B 1 72 ? 20.840 -13.968 30.136 1.00 20.58 ? 72 TYR B O 1 ATOM 3611 C CB . TYR B 1 72 ? 21.603 -17.133 30.539 1.00 23.58 ? 72 TYR B CB 1 ATOM 3612 C CG . TYR B 1 72 ? 21.470 -17.969 31.774 1.00 20.80 ? 72 TYR B CG 1 ATOM 3613 C CD1 . TYR B 1 72 ? 21.624 -17.403 33.042 1.00 22.46 ? 72 TYR B CD1 1 ATOM 3614 C CD2 . TYR B 1 72 ? 21.201 -19.327 31.694 1.00 22.84 ? 72 TYR B CD2 1 ATOM 3615 C CE1 . TYR B 1 72 ? 21.502 -18.177 34.197 1.00 19.88 ? 72 TYR B CE1 1 ATOM 3616 C CE2 . TYR B 1 72 ? 21.078 -20.100 32.827 1.00 27.16 ? 72 TYR B CE2 1 ATOM 3617 C CZ . TYR B 1 72 ? 21.235 -19.523 34.083 1.00 26.20 ? 72 TYR B CZ 1 ATOM 3618 O OH . TYR B 1 72 ? 21.124 -20.312 35.218 1.00 24.85 ? 72 TYR B OH 1 ATOM 3619 N N . PRO B 1 73 ? 20.866 -15.041 28.163 1.00 26.42 ? 73 PRO B N 1 ATOM 3620 C CA . PRO B 1 73 ? 21.067 -13.763 27.464 1.00 24.05 ? 73 PRO B CA 1 ATOM 3621 C C . PRO B 1 73 ? 19.970 -12.744 27.742 1.00 25.09 ? 73 PRO B C 1 ATOM 3622 O O . PRO B 1 73 ? 20.265 -11.585 28.072 1.00 22.18 ? 73 PRO B O 1 ATOM 3623 C CB . PRO B 1 73 ? 21.113 -14.183 25.982 1.00 23.51 ? 73 PRO B CB 1 ATOM 3624 C CG . PRO B 1 73 ? 21.626 -15.568 26.012 1.00 26.46 ? 73 PRO B CG 1 ATOM 3625 C CD . PRO B 1 73 ? 21.003 -16.192 27.247 1.00 23.10 ? 73 PRO B CD 1 ATOM 3626 N N . ASN B 1 74 ? 18.706 -13.142 27.643 1.00 21.26 ? 74 ASN B N 1 ATOM 3627 C CA . ASN B 1 74 ? 17.660 -12.140 27.801 1.00 21.88 ? 74 ASN B CA 1 ATOM 3628 C C . ASN B 1 74 ? 17.404 -11.782 29.264 1.00 21.82 ? 74 ASN B C 1 ATOM 3629 O O . ASN B 1 74 ? 17.020 -10.641 29.547 1.00 21.29 ? 74 ASN B O 1 ATOM 3630 C CB . ASN B 1 74 ? 16.387 -12.612 27.097 1.00 21.05 ? 74 ASN B CB 1 ATOM 3631 C CG . ASN B 1 74 ? 16.397 -12.248 25.621 1.00 23.62 ? 74 ASN B CG 1 ATOM 3632 O OD1 . ASN B 1 74 ? 16.058 -11.124 25.252 1.00 25.07 ? 74 ASN B OD1 1 ATOM 3633 N ND2 . ASN B 1 74 ? 16.841 -13.180 24.778 1.00 23.76 ? 74 ASN B ND2 1 ATOM 3634 N N . TYR B 1 75 ? 17.610 -12.717 30.206 1.00 19.53 ? 75 TYR B N 1 ATOM 3635 C CA . TYR B 1 75 ? 17.570 -12.325 31.616 1.00 21.28 ? 75 TYR B CA 1 ATOM 3636 C C . TYR B 1 75 ? 18.457 -11.113 31.850 1.00 18.23 ? 75 TYR B C 1 ATOM 3637 O O . TYR B 1 75 ? 18.092 -10.182 32.580 1.00 18.46 ? 75 TYR B O 1 ATOM 3638 C CB . TYR B 1 75 ? 18.054 -13.450 32.535 1.00 21.51 ? 75 TYR B CB 1 ATOM 3639 C CG . TYR B 1 75 ? 17.337 -14.778 32.523 1.00 21.54 ? 75 TYR B CG 1 ATOM 3640 C CD1 . TYR B 1 75 ? 16.030 -14.908 32.091 1.00 21.27 ? 75 TYR B CD1 1 ATOM 3641 C CD2 . TYR B 1 75 ? 17.990 -15.917 32.993 1.00 21.18 ? 75 TYR B CD2 1 ATOM 3642 C CE1 . TYR B 1 75 ? 15.396 -16.142 32.109 1.00 23.37 ? 75 TYR B CE1 1 ATOM 3643 C CE2 . TYR B 1 75 ? 17.365 -17.142 33.021 1.00 20.85 ? 75 TYR B CE2 1 ATOM 3644 C CZ . TYR B 1 75 ? 16.081 -17.256 32.586 1.00 23.53 ? 75 TYR B CZ 1 ATOM 3645 O OH . TYR B 1 75 ? 15.485 -18.489 32.604 1.00 23.29 ? 75 TYR B OH 1 ATOM 3646 N N . TYR B 1 76 ? 19.644 -11.111 31.247 1.00 18.71 ? 76 TYR B N 1 ATOM 3647 C CA . TYR B 1 76 ? 20.582 -10.037 31.545 1.00 21.19 ? 76 TYR B CA 1 ATOM 3648 C C . TYR B 1 76 ? 20.273 -8.797 30.719 1.00 20.66 ? 76 TYR B C 1 ATOM 3649 O O . TYR B 1 76 ? 20.439 -7.676 31.206 1.00 20.66 ? 76 TYR B O 1 ATOM 3650 C CB . TYR B 1 76 ? 22.024 -10.511 31.326 1.00 18.11 ? 76 TYR B CB 1 ATOM 3651 C CG . TYR B 1 76 ? 22.931 -10.243 32.518 1.00 22.34 ? 76 TYR B CG 1 ATOM 3652 C CD1 . TYR B 1 76 ? 22.499 -10.495 33.828 1.00 22.93 ? 76 TYR B CD1 1 ATOM 3653 C CD2 . TYR B 1 76 ? 24.221 -9.767 32.339 1.00 21.25 ? 76 TYR B CD2 1 ATOM 3654 C CE1 . TYR B 1 76 ? 23.337 -10.262 34.921 1.00 23.25 ? 76 TYR B CE1 1 ATOM 3655 C CE2 . TYR B 1 76 ? 25.058 -9.525 33.419 1.00 25.69 ? 76 TYR B CE2 1 ATOM 3656 C CZ . TYR B 1 76 ? 24.616 -9.783 34.710 1.00 26.81 ? 76 TYR B CZ 1 ATOM 3657 O OH . TYR B 1 76 ? 25.452 -9.546 35.788 1.00 25.62 ? 76 TYR B OH 1 ATOM 3658 N N . THR B 1 77 ? 19.773 -8.971 29.494 1.00 22.64 ? 77 THR B N 1 ATOM 3659 C CA . THR B 1 77 ? 19.269 -7.816 28.748 1.00 19.78 ? 77 THR B CA 1 ATOM 3660 C C . THR B 1 77 ? 18.193 -7.087 29.543 1.00 19.51 ? 77 THR B C 1 ATOM 3661 O O . THR B 1 77 ? 18.250 -5.858 29.702 1.00 21.22 ? 77 THR B O 1 ATOM 3662 C CB . THR B 1 77 ? 18.722 -8.257 27.384 1.00 23.58 ? 77 THR B CB 1 ATOM 3663 O OG1 . THR B 1 77 ? 19.769 -8.836 26.603 1.00 23.90 ? 77 THR B OG1 1 ATOM 3664 C CG2 . THR B 1 77 ? 18.153 -7.050 26.613 1.00 23.07 ? 77 THR B CG2 1 ATOM 3665 N N . LEU B 1 78 ? 17.201 -7.834 30.058 1.00 19.56 ? 78 LEU B N 1 ATOM 3666 C CA . LEU B 1 78 ? 16.100 -7.213 30.796 1.00 21.38 ? 78 LEU B CA 1 ATOM 3667 C C . LEU B 1 78 ? 16.608 -6.434 32.003 1.00 19.66 ? 78 LEU B C 1 ATOM 3668 O O . LEU B 1 78 ? 16.116 -5.341 32.299 1.00 21.33 ? 78 LEU B O 1 ATOM 3669 C CB . LEU B 1 78 ? 15.086 -8.272 31.244 1.00 17.66 ? 78 LEU B CB 1 ATOM 3670 C CG . LEU B 1 78 ? 14.265 -8.960 30.149 1.00 17.29 ? 78 LEU B CG 1 ATOM 3671 C CD1 . LEU B 1 78 ? 13.752 -10.331 30.580 1.00 19.34 ? 78 LEU B CD1 1 ATOM 3672 C CD2 . LEU B 1 78 ? 13.087 -8.051 29.719 1.00 17.13 ? 78 LEU B CD2 1 ATOM 3673 N N . MET B 1 79 ? 17.601 -6.970 32.713 1.00 18.76 ? 79 MET B N 1 ATOM 3674 C CA . MET B 1 79 ? 18.002 -6.361 33.974 1.00 17.48 ? 79 MET B CA 1 ATOM 3675 C C . MET B 1 79 ? 19.195 -5.419 33.853 1.00 22.42 ? 79 MET B C 1 ATOM 3676 O O . MET B 1 79 ? 19.614 -4.852 34.867 1.00 23.07 ? 79 MET B O 1 ATOM 3677 C CB . MET B 1 79 ? 18.277 -7.459 35.005 1.00 20.73 ? 79 MET B CB 1 ATOM 3678 C CG . MET B 1 79 ? 16.982 -7.964 35.647 1.00 20.04 ? 79 MET B CG 1 ATOM 3679 S SD . MET B 1 79 ? 16.502 -6.749 36.893 1.00 27.78 ? 79 MET B SD 1 ATOM 3680 C CE . MET B 1 79 ? 14.936 -7.425 37.452 1.00 23.47 ? 79 MET B CE 1 ATOM 3681 N N . THR B 1 80 ? 19.729 -5.217 32.641 1.00 22.14 ? 80 THR B N 1 ATOM 3682 C CA . THR B 1 80 ? 20.783 -4.233 32.383 1.00 22.93 ? 80 THR B CA 1 ATOM 3683 C C . THR B 1 80 ? 20.381 -3.149 31.391 1.00 24.27 ? 80 THR B C 1 ATOM 3684 O O . THR B 1 80 ? 21.019 -2.088 31.373 1.00 26.97 ? 80 THR B O 1 ATOM 3685 C CB . THR B 1 80 ? 22.055 -4.899 31.829 1.00 21.63 ? 80 THR B CB 1 ATOM 3686 O OG1 . THR B 1 80 ? 21.804 -5.430 30.521 1.00 23.77 ? 80 THR B OG1 1 ATOM 3687 C CG2 . THR B 1 80 ? 22.576 -6.007 32.769 1.00 23.86 ? 80 THR B CG2 1 ATOM 3688 N N . GLY B 1 81 ? 19.346 -3.376 30.582 1.00 23.50 ? 81 GLY B N 1 ATOM 3689 C CA . GLY B 1 81 ? 19.031 -2.482 29.476 1.00 21.06 ? 81 GLY B CA 1 ATOM 3690 C C . GLY B 1 81 ? 20.051 -2.488 28.355 1.00 27.12 ? 81 GLY B C 1 ATOM 3691 O O . GLY B 1 81 ? 20.074 -1.557 27.549 1.00 25.49 ? 81 GLY B O 1 ATOM 3692 N N . ARG B 1 82 ? 20.904 -3.506 28.281 1.00 26.36 ? 82 ARG B N 1 ATOM 3693 C CA . ARG B 1 82 ? 21.981 -3.547 27.300 1.00 26.89 ? 82 ARG B CA 1 ATOM 3694 C C . ARG B 1 82 ? 21.871 -4.799 26.446 1.00 28.87 ? 82 ARG B C 1 ATOM 3695 O O . ARG B 1 82 ? 21.417 -5.844 26.919 1.00 24.08 ? 82 ARG B O 1 ATOM 3696 C CB . ARG B 1 82 ? 23.350 -3.508 27.996 1.00 27.64 ? 82 ARG B CB 1 ATOM 3697 C CG . ARG B 1 82 ? 23.527 -2.268 28.859 1.00 24.87 ? 82 ARG B CG 1 ATOM 3698 C CD . ARG B 1 82 ? 24.774 -2.333 29.714 1.00 25.10 ? 82 ARG B CD 1 ATOM 3699 N NE . ARG B 1 82 ? 25.073 -1.021 30.272 1.00 29.60 ? 82 ARG B NE 1 ATOM 3700 C CZ . ARG B 1 82 ? 26.262 -0.674 30.752 1.00 35.23 ? 82 ARG B CZ 1 ATOM 3701 N NH1 . ARG B 1 82 ? 27.250 -1.551 30.736 1.00 32.15 ? 82 ARG B NH1 1 ATOM 3702 N NH2 . ARG B 1 82 ? 26.458 0.544 31.241 1.00 29.75 ? 82 ARG B NH2 1 ATOM 3703 N N . HIS B 1 83 ? 22.310 -4.686 25.184 1.00 20.97 ? 83 HIS B N 1 ATOM 3704 C CA . HIS B 1 83 ? 22.359 -5.836 24.287 1.00 25.92 ? 83 HIS B CA 1 ATOM 3705 C C . HIS B 1 83 ? 23.418 -6.848 24.745 1.00 22.42 ? 83 HIS B C 1 ATOM 3706 O O . HIS B 1 83 ? 24.317 -6.526 25.515 1.00 28.40 ? 83 HIS B O 1 ATOM 3707 C CB . HIS B 1 83 ? 22.650 -5.377 22.857 1.00 28.44 ? 83 HIS B CB 1 ATOM 3708 C CG . HIS B 1 83 ? 21.577 -4.506 22.276 1.00 27.69 ? 83 HIS B CG 1 ATOM 3709 N ND1 . HIS B 1 83 ? 20.345 -4.996 21.899 1.00 32.65 ? 83 HIS B ND1 1 ATOM 3710 C CD2 . HIS B 1 83 ? 21.552 -3.179 22.009 1.00 31.54 ? 83 HIS B CD2 1 ATOM 3711 C CE1 . HIS B 1 83 ? 19.609 -4.009 21.417 1.00 30.53 ? 83 HIS B CE1 1 ATOM 3712 N NE2 . HIS B 1 83 ? 20.317 -2.895 21.477 1.00 30.52 ? 83 HIS B NE2 1 ATOM 3713 N N . CYS B 1 84 ? 23.305 -8.087 24.237 1.00 27.92 ? 84 CYS B N 1 ATOM 3714 C CA . CYS B 1 84 ? 24.142 -9.184 24.726 1.00 25.08 ? 84 CYS B CA 1 ATOM 3715 C C . CYS B 1 84 ? 25.612 -8.990 24.393 1.00 32.59 ? 84 CYS B C 1 ATOM 3716 O O . CYS B 1 84 ? 26.480 -9.481 25.127 1.00 26.54 ? 84 CYS B O 1 ATOM 3717 C CB . CYS B 1 84 ? 23.681 -10.527 24.155 1.00 27.14 ? 84 CYS B CB 1 ATOM 3718 S SG . CYS B 1 84 ? 22.004 -11.003 24.629 1.00 33.47 ? 84 CYS B SG 1 ATOM 3719 N N . GLU B 1 85 ? 25.919 -8.316 23.282 1.00 33.42 ? 85 GLU B N 1 ATOM 3720 C CA . GLU B 1 85 ? 27.318 -8.024 22.993 1.00 35.43 ? 85 GLU B CA 1 ATOM 3721 C C . GLU B 1 85 ? 27.902 -7.027 23.976 1.00 30.16 ? 85 GLU B C 1 ATOM 3722 O O . GLU B 1 85 ? 29.130 -6.914 24.064 1.00 33.71 ? 85 GLU B O 1 ATOM 3723 C CB . GLU B 1 85 ? 27.478 -7.490 21.562 1.00 33.27 ? 85 GLU B CB 1 ATOM 3724 C CG . GLU B 1 85 ? 27.085 -6.031 21.418 1.00 31.81 ? 85 GLU B CG 1 ATOM 3725 C CD . GLU B 1 85 ? 27.105 -5.560 19.972 1.00 33.75 ? 85 GLU B CD 1 ATOM 3726 O OE1 . GLU B 1 85 ? 27.566 -6.321 19.096 1.00 33.21 ? 85 GLU B OE1 1 ATOM 3727 O OE2 . GLU B 1 85 ? 26.655 -4.426 19.715 1.00 36.81 ? 85 GLU B OE2 1 ATOM 3728 N N . VAL B 1 86 ? 27.063 -6.321 24.726 1.00 29.57 ? 86 VAL B N 1 ATOM 3729 C CA . VAL B 1 86 ? 27.525 -5.396 25.761 1.00 27.43 ? 86 VAL B CA 1 ATOM 3730 C C . VAL B 1 86 ? 27.609 -6.072 27.128 1.00 33.83 ? 86 VAL B C 1 ATOM 3731 O O . VAL B 1 86 ? 28.646 -6.015 27.789 1.00 30.20 ? 86 VAL B O 1 ATOM 3732 C CB . VAL B 1 86 ? 26.621 -4.146 25.809 1.00 33.57 ? 86 VAL B CB 1 ATOM 3733 C CG1 . VAL B 1 86 ? 27.074 -3.201 26.905 1.00 28.41 ? 86 VAL B CG1 1 ATOM 3734 C CG2 . VAL B 1 86 ? 26.618 -3.440 24.448 1.00 35.39 ? 86 VAL B CG2 1 ATOM 3735 N N . HIS B 1 87 ? 26.523 -6.713 27.586 1.00 28.69 ? 87 HIS B N 1 ATOM 3736 C CA . HIS B 1 87 ? 26.587 -7.315 28.918 1.00 31.68 ? 87 HIS B CA 1 ATOM 3737 C C . HIS B 1 87 ? 27.323 -8.649 28.937 1.00 27.92 ? 87 HIS B C 1 ATOM 3738 O O . HIS B 1 87 ? 27.656 -9.134 30.023 1.00 26.16 ? 87 HIS B O 1 ATOM 3739 C CB . HIS B 1 87 ? 25.180 -7.457 29.554 1.00 25.64 ? 87 HIS B CB 1 ATOM 3740 C CG . HIS B 1 87 ? 24.230 -8.359 28.823 1.00 23.14 ? 87 HIS B CG 1 ATOM 3741 N ND1 . HIS B 1 87 ? 24.465 -9.702 28.615 1.00 20.60 ? 87 HIS B ND1 1 ATOM 3742 C CD2 . HIS B 1 87 ? 23.008 -8.108 28.296 1.00 21.64 ? 87 HIS B CD2 1 ATOM 3743 C CE1 . HIS B 1 87 ? 23.440 -10.231 27.971 1.00 21.84 ? 87 HIS B CE1 1 ATOM 3744 N NE2 . HIS B 1 87 ? 22.543 -9.283 27.765 1.00 23.50 ? 87 HIS B NE2 1 ATOM 3745 N N . GLN B 1 88 ? 27.597 -9.236 27.774 1.00 27.26 ? 88 GLN B N 1 ATOM 3746 C CA . GLN B 1 88 ? 28.488 -10.357 27.499 1.00 26.79 ? 88 GLN B CA 1 ATOM 3747 C C . GLN B 1 88 ? 27.853 -11.728 27.694 1.00 29.41 ? 88 GLN B C 1 ATOM 3748 O O . GLN B 1 88 ? 28.479 -12.721 27.325 1.00 30.23 ? 88 GLN B O 1 ATOM 3749 C CB . GLN B 1 88 ? 29.798 -10.318 28.316 1.00 31.53 ? 88 GLN B CB 1 ATOM 3750 C CG . GLN B 1 88 ? 30.549 -8.991 28.258 1.00 29.37 ? 88 GLN B CG 1 ATOM 3751 C CD . GLN B 1 88 ? 31.069 -8.637 26.866 1.00 29.47 ? 88 GLN B CD 1 ATOM 3752 O OE1 . GLN B 1 88 ? 31.183 -9.492 25.986 1.00 34.77 ? 88 GLN B OE1 1 ATOM 3753 N NE2 . GLN B 1 88 ? 31.386 -7.365 26.671 1.00 32.31 ? 88 GLN B NE2 1 ATOM 3754 N N . MET B 1 89 ? 26.637 -11.843 28.244 1.00 22.72 ? 89 MET B N 1 ATOM 3755 C CA . MET B 1 89 ? 26.042 -13.172 28.388 1.00 24.92 ? 89 MET B CA 1 ATOM 3756 C C . MET B 1 89 ? 25.340 -13.517 27.073 1.00 29.00 ? 89 MET B C 1 ATOM 3757 O O . MET B 1 89 ? 24.155 -13.236 26.874 1.00 26.56 ? 89 MET B O 1 ATOM 3758 C CB . MET B 1 89 ? 25.119 -13.222 29.604 1.00 23.42 ? 89 MET B CB 1 ATOM 3759 C CG . MET B 1 89 ? 25.847 -12.796 30.878 1.00 26.03 ? 89 MET B CG 1 ATOM 3760 S SD . MET B 1 89 ? 25.016 -13.245 32.427 1.00 26.23 ? 89 MET B SD 1 ATOM 3761 C CE . MET B 1 89 ? 25.316 -15.005 32.477 1.00 24.64 ? 89 MET B CE 1 ATOM 3762 N N . ILE B 1 90 ? 26.090 -14.135 26.150 1.00 29.63 ? 90 ILE B N 1 ATOM 3763 C CA . ILE B 1 90 ? 25.629 -14.279 24.765 1.00 24.83 ? 90 ILE B CA 1 ATOM 3764 C C . ILE B 1 90 ? 25.041 -15.654 24.476 1.00 31.83 ? 90 ILE B C 1 ATOM 3765 O O . ILE B 1 90 ? 24.543 -15.879 23.360 1.00 30.47 ? 90 ILE B O 1 ATOM 3766 C CB . ILE B 1 90 ? 26.758 -13.946 23.764 1.00 25.10 ? 90 ILE B CB 1 ATOM 3767 C CG1 . ILE B 1 90 ? 28.045 -14.721 24.078 1.00 29.87 ? 90 ILE B CG1 1 ATOM 3768 C CG2 . ILE B 1 90 ? 27.089 -12.457 23.807 1.00 28.98 ? 90 ILE B CG2 1 ATOM 3769 C CD1 . ILE B 1 90 ? 28.116 -16.128 23.510 1.00 27.52 ? 90 ILE B CD1 1 ATOM 3770 N N . GLY B 1 91 ? 25.038 -16.565 25.448 1.00 25.91 ? 91 GLY B N 1 ATOM 3771 C CA . GLY B 1 91 ? 24.455 -17.873 25.233 1.00 25.67 ? 91 GLY B CA 1 ATOM 3772 C C . GLY B 1 91 ? 23.964 -18.491 26.523 1.00 24.24 ? 91 GLY B C 1 ATOM 3773 O O . GLY B 1 91 ? 24.301 -18.042 27.618 1.00 27.13 ? 91 GLY B O 1 ATOM 3774 N N . ASN B 1 92 ? 23.129 -19.522 26.383 1.00 26.20 ? 92 ASN B N 1 ATOM 3775 C CA . ASN B 1 92 ? 22.874 -20.386 27.524 1.00 21.17 ? 92 ASN B CA 1 ATOM 3776 C C . ASN B 1 92 ? 24.102 -21.217 27.841 1.00 30.50 ? 92 ASN B C 1 ATOM 3777 O O . ASN B 1 92 ? 24.338 -21.550 29.003 1.00 26.63 ? 92 ASN B O 1 ATOM 3778 C CB . ASN B 1 92 ? 21.688 -21.305 27.267 1.00 25.97 ? 92 ASN B CB 1 ATOM 3779 C CG . ASN B 1 92 ? 20.358 -20.615 27.493 1.00 27.80 ? 92 ASN B CG 1 ATOM 3780 O OD1 . ASN B 1 92 ? 20.283 -19.574 28.153 1.00 25.58 ? 92 ASN B OD1 1 ATOM 3781 N ND2 . ASN B 1 92 ? 19.304 -21.211 26.980 1.00 25.34 ? 92 ASN B ND2 1 ATOM 3782 N N . TYR B 1 93 ? 24.893 -21.539 26.822 1.00 31.35 ? 93 TYR B N 1 ATOM 3783 C CA . TYR B 1 93 ? 26.133 -22.288 26.964 1.00 31.24 ? 93 TYR B CA 1 ATOM 3784 C C . TYR B 1 93 ? 27.260 -21.453 26.389 1.00 29.97 ? 93 TYR B C 1 ATOM 3785 O O . TYR B 1 93 ? 27.167 -20.986 25.248 1.00 33.07 ? 93 TYR B O 1 ATOM 3786 C CB . TYR B 1 93 ? 26.058 -23.627 26.240 1.00 29.85 ? 93 TYR B CB 1 ATOM 3787 C CG . TYR B 1 93 ? 25.030 -24.574 26.795 1.00 37.10 ? 93 TYR B CG 1 ATOM 3788 C CD1 . TYR B 1 93 ? 23.683 -24.427 26.490 1.00 32.08 ? 93 TYR B CD1 1 ATOM 3789 C CD2 . TYR B 1 93 ? 25.411 -25.637 27.605 1.00 29.95 ? 93 TYR B CD2 1 ATOM 3790 C CE1 . TYR B 1 93 ? 22.739 -25.303 26.992 1.00 35.33 ? 93 TYR B CE1 1 ATOM 3791 C CE2 . TYR B 1 93 ? 24.479 -26.515 28.108 1.00 29.70 ? 93 TYR B CE2 1 ATOM 3792 C CZ . TYR B 1 93 ? 23.143 -26.344 27.800 1.00 43.44 ? 93 TYR B CZ 1 ATOM 3793 O OH . TYR B 1 93 ? 22.203 -27.220 28.299 1.00 48.51 ? 93 TYR B OH 1 ATOM 3794 N N . MET B 1 94 ? 28.316 -21.254 27.176 1.00 29.44 ? 94 MET B N 1 ATOM 3795 C CA . MET B 1 94 ? 29.446 -20.442 26.757 1.00 28.69 ? 94 MET B CA 1 ATOM 3796 C C . MET B 1 94 ? 30.745 -21.122 27.169 1.00 32.36 ? 94 MET B C 1 ATOM 3797 O O . MET B 1 94 ? 30.766 -22.037 27.997 1.00 33.51 ? 94 MET B O 1 ATOM 3798 C CB . MET B 1 94 ? 29.386 -19.030 27.338 1.00 27.25 ? 94 MET B CB 1 ATOM 3799 C CG . MET B 1 94 ? 28.139 -18.228 26.913 1.00 25.76 ? 94 MET B CG 1 ATOM 3800 S SD . MET B 1 94 ? 28.124 -16.578 27.630 1.00 29.67 ? 94 MET B SD 1 ATOM 3801 C CE . MET B 1 94 ? 27.549 -16.918 29.312 1.00 29.10 ? 94 MET B CE 1 ATOM 3802 N N . TRP B 1 95 ? 31.836 -20.646 26.573 1.00 39.02 ? 95 TRP B N 1 ATOM 3803 C CA . TRP B 1 95 ? 33.163 -21.215 26.774 1.00 38.55 ? 95 TRP B CA 1 ATOM 3804 C C . TRP B 1 95 ? 34.194 -20.104 26.674 1.00 39.77 ? 95 TRP B C 1 ATOM 3805 O O . TRP B 1 95 ? 34.159 -19.307 25.731 1.00 39.07 ? 95 TRP B O 1 ATOM 3806 C CB . TRP B 1 95 ? 33.450 -22.299 25.735 1.00 40.41 ? 95 TRP B CB 1 ATOM 3807 C CG . TRP B 1 95 ? 34.712 -23.048 25.986 1.00 45.15 ? 95 TRP B CG 1 ATOM 3808 C CD1 . TRP B 1 95 ? 35.044 -23.733 27.117 1.00 51.73 ? 95 TRP B CD1 1 ATOM 3809 C CD2 . TRP B 1 95 ? 35.808 -23.208 25.082 1.00 50.52 ? 95 TRP B CD2 1 ATOM 3810 N NE1 . TRP B 1 95 ? 36.286 -24.306 26.977 1.00 55.27 ? 95 TRP B NE1 1 ATOM 3811 C CE2 . TRP B 1 95 ? 36.775 -24.001 25.733 1.00 53.99 ? 95 TRP B CE2 1 ATOM 3812 C CE3 . TRP B 1 95 ? 36.068 -22.758 23.784 1.00 52.59 ? 95 TRP B CE3 1 ATOM 3813 C CZ2 . TRP B 1 95 ? 37.983 -24.352 25.131 1.00 54.15 ? 95 TRP B CZ2 1 ATOM 3814 C CZ3 . TRP B 1 95 ? 37.268 -23.110 23.186 1.00 58.63 ? 95 TRP B CZ3 1 ATOM 3815 C CH2 . TRP B 1 95 ? 38.211 -23.896 23.860 1.00 54.76 ? 95 TRP B CH2 1 ATOM 3816 N N . ASP B 1 96 ? 35.096 -20.043 27.655 1.00 45.39 ? 96 ASP B N 1 ATOM 3817 C CA . ASP B 1 96 ? 36.212 -19.112 27.600 1.00 43.64 ? 96 ASP B CA 1 ATOM 3818 C C . ASP B 1 96 ? 37.452 -19.895 27.203 1.00 54.71 ? 96 ASP B C 1 ATOM 3819 O O . ASP B 1 96 ? 38.064 -20.554 28.060 1.00 48.13 ? 96 ASP B O 1 ATOM 3820 C CB . ASP B 1 96 ? 36.423 -18.408 28.941 1.00 47.47 ? 96 ASP B CB 1 ATOM 3821 C CG . ASP B 1 96 ? 37.488 -17.322 28.868 1.00 54.74 ? 96 ASP B CG 1 ATOM 3822 O OD1 . ASP B 1 96 ? 37.903 -16.958 27.746 1.00 54.04 ? 96 ASP B OD1 1 ATOM 3823 O OD2 . ASP B 1 96 ? 37.905 -16.825 29.935 1.00 57.40 ? 96 ASP B OD2 1 ATOM 3824 N N . PRO B 1 97 ? 37.853 -19.878 25.930 1.00 51.81 ? 97 PRO B N 1 ATOM 3825 C CA . PRO B 1 97 ? 39.054 -20.624 25.526 1.00 54.74 ? 97 PRO B CA 1 ATOM 3826 C C . PRO B 1 97 ? 40.314 -20.143 26.216 1.00 55.35 ? 97 PRO B C 1 ATOM 3827 O O . PRO B 1 97 ? 41.312 -20.875 26.239 1.00 58.87 ? 97 PRO B O 1 ATOM 3828 C CB . PRO B 1 97 ? 39.117 -20.385 24.013 1.00 59.47 ? 97 PRO B CB 1 ATOM 3829 C CG . PRO B 1 97 ? 38.406 -19.080 23.819 1.00 56.80 ? 97 PRO B CG 1 ATOM 3830 C CD . PRO B 1 97 ? 37.291 -19.088 24.822 1.00 49.06 ? 97 PRO B CD 1 ATOM 3831 N N . ARG B 1 98 ? 40.299 -18.936 26.780 1.00 56.06 ? 98 ARG B N 1 ATOM 3832 C CA . ARG B 1 98 ? 41.471 -18.437 27.488 1.00 55.93 ? 98 ARG B CA 1 ATOM 3833 C C . ARG B 1 98 ? 41.668 -19.159 28.819 1.00 61.81 ? 98 ARG B C 1 ATOM 3834 O O . ARG B 1 98 ? 42.806 -19.439 29.215 1.00 58.34 ? 98 ARG B O 1 ATOM 3835 C CB . ARG B 1 98 ? 41.337 -16.930 27.691 1.00 56.60 ? 98 ARG B CB 1 ATOM 3836 C CG . ARG B 1 98 ? 42.468 -16.293 28.466 1.00 58.14 ? 98 ARG B CG 1 ATOM 3837 C CD . ARG B 1 98 ? 42.136 -14.842 28.732 1.00 70.91 ? 98 ARG B CD 1 ATOM 3838 N NE . ARG B 1 98 ? 40.722 -14.699 29.063 1.00 72.79 ? 98 ARG B NE 1 ATOM 3839 C CZ . ARG B 1 98 ? 40.232 -14.778 30.296 1.00 73.61 ? 98 ARG B CZ 1 ATOM 3840 N NH1 . ARG B 1 98 ? 41.049 -14.985 31.322 1.00 69.87 ? 98 ARG B NH1 1 ATOM 3841 N NH2 . ARG B 1 98 ? 38.925 -14.646 30.502 1.00 64.15 ? 98 ARG B NH2 1 ATOM 3842 N N . THR B 1 99 ? 40.576 -19.481 29.516 1.00 55.81 ? 99 THR B N 1 ATOM 3843 C CA . THR B 1 99 ? 40.650 -20.165 30.801 1.00 52.86 ? 99 THR B CA 1 ATOM 3844 C C . THR B 1 99 ? 40.180 -21.611 30.750 1.00 52.35 ? 99 THR B C 1 ATOM 3845 O O . THR B 1 99 ? 40.205 -22.287 31.785 1.00 57.16 ? 99 THR B O 1 ATOM 3846 C CB . THR B 1 99 ? 39.832 -19.411 31.855 1.00 55.48 ? 99 THR B CB 1 ATOM 3847 O OG1 . THR B 1 99 ? 38.452 -19.388 31.468 1.00 58.49 ? 99 THR B OG1 1 ATOM 3848 C CG2 . THR B 1 99 ? 40.335 -17.993 31.997 1.00 54.10 ? 99 THR B CG2 1 ATOM 3849 N N . ASN B 1 100 ? 39.749 -22.100 29.587 1.00 53.69 ? 100 ASN B N 1 ATOM 3850 C CA . ASN B 1 100 ? 39.214 -23.451 29.426 1.00 54.12 ? 100 ASN B CA 1 ATOM 3851 C C . ASN B 1 100 ? 38.006 -23.706 30.334 1.00 55.81 ? 100 ASN B C 1 ATOM 3852 O O . ASN B 1 100 ? 37.707 -24.858 30.671 1.00 55.03 ? 100 ASN B O 1 ATOM 3853 C CB . ASN B 1 100 ? 40.305 -24.509 29.664 1.00 58.62 ? 100 ASN B CB 1 ATOM 3854 C CG . ASN B 1 100 ? 39.951 -25.863 29.073 1.00 61.59 ? 100 ASN B CG 1 ATOM 3855 O OD1 . ASN B 1 100 ? 39.007 -25.981 28.293 1.00 68.43 ? 100 ASN B OD1 1 ATOM 3856 N ND2 . ASN B 1 100 ? 40.714 -26.892 29.438 1.00 65.79 ? 100 ASN B ND2 1 ATOM 3857 N N . LYS B 1 101 ? 37.298 -22.648 30.730 1.00 47.33 ? 101 LYS B N 1 ATOM 3858 C CA . LYS B 1 101 ? 36.141 -22.750 31.611 1.00 45.21 ? 101 LYS B CA 1 ATOM 3859 C C . LYS B 1 101 ? 34.852 -22.520 30.825 1.00 43.75 ? 101 LYS B C 1 ATOM 3860 O O . LYS B 1 101 ? 34.817 -21.732 29.875 1.00 41.75 ? 101 LYS B O 1 ATOM 3861 C CB . LYS B 1 101 ? 36.239 -21.739 32.757 1.00 41.29 ? 101 LYS B CB 1 ATOM 3862 C CG . LYS B 1 101 ? 37.507 -21.844 33.609 1.00 50.44 ? 101 LYS B CG 1 ATOM 3863 C CD . LYS B 1 101 ? 37.318 -22.781 34.798 1.00 57.09 ? 101 LYS B CD 1 ATOM 3864 C CE . LYS B 1 101 ? 38.493 -22.712 35.768 1.00 54.99 ? 101 LYS B CE 1 ATOM 3865 N NZ . LYS B 1 101 ? 39.785 -23.013 35.091 1.00 59.49 ? 101 LYS B NZ 1 ATOM 3866 N N . SER B 1 102 ? 33.789 -23.213 31.241 1.00 36.04 ? 102 SER B N 1 ATOM 3867 C CA . SER B 1 102 ? 32.506 -23.206 30.548 1.00 37.11 ? 102 SER B CA 1 ATOM 3868 C C . SER B 1 102 ? 31.384 -22.689 31.443 1.00 34.29 ? 102 SER B C 1 ATOM 3869 O O . SER B 1 102 ? 31.426 -22.829 32.668 1.00 32.24 ? 102 SER B O 1 ATOM 3870 C CB . SER B 1 102 ? 32.134 -24.611 30.055 1.00 38.73 ? 102 SER B CB 1 ATOM 3871 O OG . SER B 1 102 ? 32.919 -24.998 28.942 1.00 44.08 ? 102 SER B OG 1 ATOM 3872 N N . PHE B 1 103 ? 30.366 -22.102 30.806 1.00 33.21 ? 103 PHE B N 1 ATOM 3873 C CA . PHE B 1 103 ? 29.089 -21.766 31.439 1.00 34.18 ? 103 PHE B CA 1 ATOM 3874 C C . PHE B 1 103 ? 28.046 -22.656 30.764 1.00 30.42 ? 103 PHE B C 1 ATOM 3875 O O . PHE B 1 103 ? 27.710 -22.451 29.595 1.00 30.95 ? 103 PHE B O 1 ATOM 3876 C CB . PHE B 1 103 ? 28.792 -20.271 31.282 1.00 28.44 ? 103 PHE B CB 1 ATOM 3877 C CG . PHE B 1 103 ? 27.471 -19.831 31.875 1.00 29.40 ? 103 PHE B CG 1 ATOM 3878 C CD1 . PHE B 1 103 ? 26.278 -20.090 31.218 1.00 29.19 ? 103 PHE B CD1 1 ATOM 3879 C CD2 . PHE B 1 103 ? 27.431 -19.122 33.070 1.00 28.82 ? 103 PHE B CD2 1 ATOM 3880 C CE1 . PHE B 1 103 ? 25.062 -19.680 31.757 1.00 27.42 ? 103 PHE B CE1 1 ATOM 3881 C CE2 . PHE B 1 103 ? 26.217 -18.706 33.609 1.00 27.14 ? 103 PHE B CE2 1 ATOM 3882 C CZ . PHE B 1 103 ? 25.040 -18.998 32.962 1.00 26.55 ? 103 PHE B CZ 1 ATOM 3883 N N . ASP B 1 104 ? 27.567 -23.672 31.478 1.00 29.73 ? 104 ASP B N 1 ATOM 3884 C CA . ASP B 1 104 ? 26.668 -24.683 30.920 1.00 26.68 ? 104 ASP B CA 1 ATOM 3885 C C . ASP B 1 104 ? 25.282 -24.492 31.529 1.00 27.86 ? 104 ASP B C 1 ATOM 3886 O O . ASP B 1 104 ? 24.882 -25.193 32.459 1.00 29.17 ? 104 ASP B O 1 ATOM 3887 C CB . ASP B 1 104 ? 27.207 -26.104 31.160 1.00 31.81 ? 104 ASP B CB 1 ATOM 3888 C CG . ASP B 1 104 ? 28.455 -26.395 30.346 1.00 40.37 ? 104 ASP B CG 1 ATOM 3889 O OD1 . ASP B 1 104 ? 28.673 -25.707 29.324 1.00 36.87 ? 104 ASP B OD1 1 ATOM 3890 O OD2 . ASP B 1 104 ? 29.212 -27.316 30.725 1.00 44.05 ? 104 ASP B OD2 1 ATOM 3891 N N . ILE B 1 105 ? 24.547 -23.529 30.965 1.00 30.76 ? 105 ILE B N 1 ATOM 3892 C CA . ILE B 1 105 ? 23.198 -23.123 31.358 1.00 29.17 ? 105 ILE B CA 1 ATOM 3893 C C . ILE B 1 105 ? 23.040 -23.072 32.879 1.00 26.33 ? 105 ILE B C 1 ATOM 3894 O O . ILE B 1 105 ? 21.994 -23.432 33.430 1.00 24.83 ? 105 ILE B O 1 ATOM 3895 C CB . ILE B 1 105 ? 22.128 -24.002 30.663 1.00 27.57 ? 105 ILE B CB 1 ATOM 3896 C CG1 . ILE B 1 105 ? 20.777 -23.262 30.614 1.00 30.70 ? 105 ILE B CG1 1 ATOM 3897 C CG2 . ILE B 1 105 ? 22.004 -25.416 31.253 1.00 30.88 ? 105 ILE B CG2 1 ATOM 3898 C CD1 . ILE B 1 105 ? 19.738 -23.922 29.717 1.00 32.38 ? 105 ILE B CD1 1 ATOM 3899 N N . GLY B 1 106 ? 24.068 -22.562 33.557 1.00 23.72 ? 106 GLY B N 1 ATOM 3900 C CA . GLY B 1 106 ? 24.000 -22.319 34.985 1.00 28.97 ? 106 GLY B CA 1 ATOM 3901 C C . GLY B 1 106 ? 24.147 -23.535 35.875 1.00 30.73 ? 106 GLY B C 1 ATOM 3902 O O . GLY B 1 106 ? 24.032 -23.401 37.098 1.00 29.22 ? 106 GLY B O 1 ATOM 3903 N N . VAL B 1 107 ? 24.413 -24.713 35.316 1.00 28.77 ? 107 VAL B N 1 ATOM 3904 C CA . VAL B 1 107 ? 24.312 -25.946 36.099 1.00 26.41 ? 107 VAL B CA 1 ATOM 3905 C C . VAL B 1 107 ? 25.659 -26.353 36.689 1.00 33.69 ? 107 VAL B C 1 ATOM 3906 O O . VAL B 1 107 ? 25.735 -26.763 37.850 1.00 28.74 ? 107 VAL B O 1 ATOM 3907 C CB . VAL B 1 107 ? 23.704 -27.068 35.231 1.00 31.57 ? 107 VAL B CB 1 ATOM 3908 C CG1 . VAL B 1 107 ? 23.801 -28.414 35.940 1.00 31.73 ? 107 VAL B CG1 1 ATOM 3909 C CG2 . VAL B 1 107 ? 22.241 -26.769 34.930 1.00 30.85 ? 107 VAL B CG2 1 ATOM 3910 N N . ASN B 1 108 ? 26.732 -26.246 35.913 1.00 32.70 ? 108 ASN B N 1 ATOM 3911 C CA . ASN B 1 108 ? 28.051 -26.594 36.418 1.00 30.16 ? 108 ASN B CA 1 ATOM 3912 C C . ASN B 1 108 ? 28.559 -25.515 37.363 1.00 36.02 ? 108 ASN B C 1 ATOM 3913 O O . ASN B 1 108 ? 28.149 -24.348 37.297 1.00 28.46 ? 108 ASN B O 1 ATOM 3914 C CB . ASN B 1 108 ? 29.031 -26.787 35.262 1.00 27.56 ? 108 ASN B CB 1 ATOM 3915 C CG . ASN B 1 108 ? 29.258 -25.521 34.471 1.00 32.24 ? 108 ASN B CG 1 ATOM 3916 O OD1 . ASN B 1 108 ? 28.307 -24.807 34.114 1.00 30.21 ? 108 ASN B OD1 1 ATOM 3917 N ND2 . ASN B 1 108 ? 30.516 -25.235 34.178 1.00 27.55 ? 108 ASN B ND2 1 ATOM 3918 N N . ARG B 1 109 ? 29.483 -25.910 38.239 1.00 29.32 ? 109 ARG B N 1 ATOM 3919 C CA . ARG B 1 109 ? 29.889 -25.006 39.310 1.00 28.72 ? 109 ARG B CA 1 ATOM 3920 C C . ARG B 1 109 ? 30.583 -23.772 38.756 1.00 25.66 ? 109 ARG B C 1 ATOM 3921 O O . ARG B 1 109 ? 30.449 -22.676 39.313 1.00 26.04 ? 109 ARG B O 1 ATOM 3922 C CB . ARG B 1 109 ? 30.794 -25.730 40.311 1.00 27.39 ? 109 ARG B CB 1 ATOM 3923 C CG . ARG B 1 109 ? 31.153 -24.842 41.486 1.00 26.36 ? 109 ARG B CG 1 ATOM 3924 C CD . ARG B 1 109 ? 32.053 -25.534 42.508 1.00 30.25 ? 109 ARG B CD 1 ATOM 3925 N NE . ARG B 1 109 ? 32.277 -24.619 43.620 1.00 28.20 ? 109 ARG B NE 1 ATOM 3926 C CZ . ARG B 1 109 ? 32.540 -24.994 44.860 1.00 34.46 ? 109 ARG B CZ 1 ATOM 3927 N NH1 . ARG B 1 109 ? 32.625 -26.285 45.158 1.00 29.73 ? 109 ARG B NH1 1 ATOM 3928 N NH2 . ARG B 1 109 ? 32.715 -24.074 45.800 1.00 30.52 ? 109 ARG B NH2 1 ATOM 3929 N N . ASP B 1 110 ? 31.304 -23.917 37.640 1.00 24.86 ? 110 ASP B N 1 ATOM 3930 C CA . ASP B 1 110 ? 31.992 -22.758 37.089 1.00 26.50 ? 110 ASP B CA 1 ATOM 3931 C C . ASP B 1 110 ? 31.027 -21.722 36.511 1.00 25.86 ? 110 ASP B C 1 ATOM 3932 O O . ASP B 1 110 ? 31.472 -20.623 36.176 1.00 24.40 ? 110 ASP B O 1 ATOM 3933 C CB . ASP B 1 110 ? 32.997 -23.181 36.017 1.00 32.94 ? 110 ASP B CB 1 ATOM 3934 C CG . ASP B 1 110 ? 34.258 -23.810 36.609 1.00 43.74 ? 110 ASP B CG 1 ATOM 3935 O OD1 . ASP B 1 110 ? 34.585 -23.522 37.785 1.00 39.92 ? 110 ASP B OD1 1 ATOM 3936 O OD2 . ASP B 1 110 ? 34.925 -24.586 35.893 1.00 40.79 ? 110 ASP B OD2 1 ATOM 3937 N N . SER B 1 111 ? 29.731 -22.037 36.408 1.00 28.32 ? 111 SER B N 1 ATOM 3938 C CA . SER B 1 111 ? 28.746 -21.016 36.039 1.00 26.27 ? 111 SER B CA 1 ATOM 3939 C C . SER B 1 111 ? 28.643 -19.913 37.084 1.00 29.05 ? 111 SER B C 1 ATOM 3940 O O . SER B 1 111 ? 28.152 -18.819 36.776 1.00 30.47 ? 111 SER B O 1 ATOM 3941 C CB . SER B 1 111 ? 27.366 -21.639 35.850 1.00 24.74 ? 111 SER B CB 1 ATOM 3942 O OG . SER B 1 111 ? 27.274 -22.373 34.646 1.00 27.01 ? 111 SER B OG 1 ATOM 3943 N N . LEU B 1 112 ? 29.080 -20.180 38.311 1.00 24.14 ? 112 LEU B N 1 ATOM 3944 C CA . LEU B 1 112 ? 29.063 -19.208 39.393 1.00 25.40 ? 112 LEU B CA 1 ATOM 3945 C C . LEU B 1 112 ? 30.221 -18.226 39.330 1.00 21.67 ? 112 LEU B C 1 ATOM 3946 O O . LEU B 1 112 ? 30.275 -17.306 40.157 1.00 26.61 ? 112 LEU B O 1 ATOM 3947 C CB . LEU B 1 112 ? 29.083 -19.944 40.738 1.00 26.92 ? 112 LEU B CB 1 ATOM 3948 C CG . LEU B 1 112 ? 27.881 -20.838 41.040 1.00 30.45 ? 112 LEU B CG 1 ATOM 3949 C CD1 . LEU B 1 112 ? 28.170 -21.706 42.255 1.00 31.28 ? 112 LEU B CD1 1 ATOM 3950 C CD2 . LEU B 1 112 ? 26.657 -19.991 41.276 1.00 25.70 ? 112 LEU B CD2 1 ATOM 3951 N N . MET B 1 113 ? 31.149 -18.399 38.393 1.00 25.44 ? 113 MET B N 1 ATOM 3952 C CA . MET B 1 113 ? 32.307 -17.510 38.322 1.00 28.78 ? 113 MET B CA 1 ATOM 3953 C C . MET B 1 113 ? 31.864 -16.125 37.875 1.00 33.31 ? 113 MET B C 1 ATOM 3954 O O . MET B 1 113 ? 31.139 -16.008 36.875 1.00 30.70 ? 113 MET B O 1 ATOM 3955 C CB . MET B 1 113 ? 33.363 -18.034 37.347 1.00 28.83 ? 113 MET B CB 1 ATOM 3956 C CG . MET B 1 113 ? 34.001 -19.347 37.739 1.00 31.06 ? 113 MET B CG 1 ATOM 3957 S SD . MET B 1 113 ? 35.166 -19.903 36.475 1.00 50.04 ? 113 MET B SD 1 ATOM 3958 C CE . MET B 1 113 ? 36.213 -18.455 36.325 1.00 35.67 ? 113 MET B CE 1 ATOM 3959 N N . PRO B 1 114 ? 32.282 -15.063 38.570 1.00 33.29 ? 114 PRO B N 1 ATOM 3960 C CA . PRO B 1 114 ? 31.925 -13.703 38.134 1.00 30.55 ? 114 PRO B CA 1 ATOM 3961 C C . PRO B 1 114 ? 32.415 -13.358 36.738 1.00 34.41 ? 114 PRO B C 1 ATOM 3962 O O . PRO B 1 114 ? 31.904 -12.393 36.157 1.00 34.85 ? 114 PRO B O 1 ATOM 3963 C CB . PRO B 1 114 ? 32.586 -12.809 39.190 1.00 30.95 ? 114 PRO B CB 1 ATOM 3964 C CG . PRO B 1 114 ? 32.736 -13.702 40.411 1.00 36.97 ? 114 PRO B CG 1 ATOM 3965 C CD . PRO B 1 114 ? 33.031 -15.068 39.840 1.00 36.99 ? 114 PRO B CD 1 ATOM 3966 N N . LEU B 1 115 ? 33.383 -14.106 36.194 1.00 32.15 ? 115 LEU B N 1 ATOM 3967 C CA . LEU B 1 115 ? 33.805 -13.928 34.803 1.00 33.94 ? 115 LEU B CA 1 ATOM 3968 C C . LEU B 1 115 ? 32.616 -13.850 33.844 1.00 31.80 ? 115 LEU B C 1 ATOM 3969 O O . LEU B 1 115 ? 32.624 -13.062 32.890 1.00 31.63 ? 115 LEU B O 1 ATOM 3970 C CB . LEU B 1 115 ? 34.720 -15.083 34.396 1.00 30.07 ? 115 LEU B CB 1 ATOM 3971 C CG . LEU B 1 115 ? 35.065 -15.168 32.909 1.00 40.00 ? 115 LEU B CG 1 ATOM 3972 C CD1 . LEU B 1 115 ? 36.155 -14.159 32.535 1.00 39.41 ? 115 LEU B CD1 1 ATOM 3973 C CD2 . LEU B 1 115 ? 35.447 -16.587 32.511 1.00 41.35 ? 115 LEU B CD2 1 ATOM 3974 N N . TRP B 1 116 ? 31.591 -14.668 34.075 1.00 31.35 ? 116 TRP B N 1 ATOM 3975 C CA . TRP B 1 116 ? 30.441 -14.722 33.176 1.00 29.47 ? 116 TRP B CA 1 ATOM 3976 C C . TRP B 1 116 ? 29.451 -13.589 33.408 1.00 26.06 ? 116 TRP B C 1 ATOM 3977 O O . TRP B 1 116 ? 28.637 -13.299 32.520 1.00 28.08 ? 116 TRP B O 1 ATOM 3978 C CB . TRP B 1 116 ? 29.707 -16.052 33.344 1.00 30.52 ? 116 TRP B CB 1 ATOM 3979 C CG . TRP B 1 116 ? 30.586 -17.277 33.232 1.00 29.21 ? 116 TRP B CG 1 ATOM 3980 C CD1 . TRP B 1 116 ? 30.917 -18.150 34.234 1.00 29.76 ? 116 TRP B CD1 1 ATOM 3981 C CD2 . TRP B 1 116 ? 31.230 -17.759 32.048 1.00 30.60 ? 116 TRP B CD2 1 ATOM 3982 N NE1 . TRP B 1 116 ? 31.732 -19.152 33.740 1.00 30.54 ? 116 TRP B NE1 1 ATOM 3983 C CE2 . TRP B 1 116 ? 31.944 -18.926 32.402 1.00 29.35 ? 116 TRP B CE2 1 ATOM 3984 C CE3 . TRP B 1 116 ? 31.287 -17.309 30.724 1.00 33.88 ? 116 TRP B CE3 1 ATOM 3985 C CZ2 . TRP B 1 116 ? 32.689 -19.650 31.477 1.00 27.77 ? 116 TRP B CZ2 1 ATOM 3986 C CZ3 . TRP B 1 116 ? 32.028 -18.035 29.806 1.00 33.56 ? 116 TRP B CZ3 1 ATOM 3987 C CH2 . TRP B 1 116 ? 32.726 -19.191 30.191 1.00 35.68 ? 116 TRP B CH2 1 ATOM 3988 N N . TRP B 1 117 ? 29.499 -12.954 34.575 1.00 24.38 ? 117 TRP B N 1 ATOM 3989 C CA . TRP B 1 117 ? 28.461 -12.049 35.040 1.00 26.43 ? 117 TRP B CA 1 ATOM 3990 C C . TRP B 1 117 ? 28.920 -10.606 35.141 1.00 25.93 ? 117 TRP B C 1 ATOM 3991 O O . TRP B 1 117 ? 28.073 -9.712 35.218 1.00 23.38 ? 117 TRP B O 1 ATOM 3992 C CB . TRP B 1 117 ? 27.947 -12.508 36.419 1.00 22.75 ? 117 TRP B CB 1 ATOM 3993 C CG . TRP B 1 117 ? 27.363 -13.889 36.389 1.00 23.25 ? 117 TRP B CG 1 ATOM 3994 C CD1 . TRP B 1 117 ? 28.028 -15.075 36.557 1.00 25.51 ? 117 TRP B CD1 1 ATOM 3995 C CD2 . TRP B 1 117 ? 25.994 -14.222 36.173 1.00 23.89 ? 117 TRP B CD2 1 ATOM 3996 N NE1 . TRP B 1 117 ? 27.149 -16.128 36.457 1.00 26.33 ? 117 TRP B NE1 1 ATOM 3997 C CE2 . TRP B 1 117 ? 25.892 -15.627 36.213 1.00 23.47 ? 117 TRP B CE2 1 ATOM 3998 C CE3 . TRP B 1 117 ? 24.834 -13.464 35.941 1.00 24.34 ? 117 TRP B CE3 1 ATOM 3999 C CZ2 . TRP B 1 117 ? 24.683 -16.292 36.040 1.00 23.99 ? 117 TRP B CZ2 1 ATOM 4000 C CZ3 . TRP B 1 117 ? 23.632 -14.130 35.772 1.00 23.10 ? 117 TRP B CZ3 1 ATOM 4001 C CH2 . TRP B 1 117 ? 23.563 -15.527 35.814 1.00 25.54 ? 117 TRP B CH2 1 ATOM 4002 N N . ASN B 1 118 ? 30.230 -10.352 35.140 1.00 25.74 ? 118 ASN B N 1 ATOM 4003 C CA . ASN B 1 118 ? 30.725 -9.018 35.472 1.00 26.54 ? 118 ASN B CA 1 ATOM 4004 C C . ASN B 1 118 ? 30.724 -8.060 34.284 1.00 27.78 ? 118 ASN B C 1 ATOM 4005 O O . ASN B 1 118 ? 31.137 -6.906 34.444 1.00 32.45 ? 118 ASN B O 1 ATOM 4006 C CB . ASN B 1 118 ? 32.135 -9.130 36.088 1.00 31.71 ? 118 ASN B CB 1 ATOM 4007 C CG . ASN B 1 118 ? 32.093 -9.437 37.592 1.00 32.04 ? 118 ASN B CG 1 ATOM 4008 O OD1 . ASN B 1 118 ? 31.015 -9.627 38.153 1.00 29.79 ? 118 ASN B OD1 1 ATOM 4009 N ND2 . ASN B 1 118 ? 33.263 -9.473 38.254 1.00 37.76 ? 118 ASN B ND2 1 ATOM 4010 N N . GLY B 1 119 ? 30.220 -8.488 33.121 1.00 31.94 ? 119 GLY B N 1 ATOM 4011 C CA . GLY B 1 119 ? 30.309 -7.671 31.918 1.00 30.07 ? 119 GLY B CA 1 ATOM 4012 C C . GLY B 1 119 ? 29.403 -6.454 31.918 1.00 35.33 ? 119 GLY B C 1 ATOM 4013 O O . GLY B 1 119 ? 29.588 -5.542 31.103 1.00 33.07 ? 119 GLY B O 1 ATOM 4014 N N . SER B 1 120 ? 28.395 -6.435 32.793 1.00 29.82 ? 120 SER B N 1 ATOM 4015 C CA . SER B 1 120 ? 27.606 -5.236 33.070 1.00 27.75 ? 120 SER B CA 1 ATOM 4016 C C . SER B 1 120 ? 26.909 -5.432 34.406 1.00 27.52 ? 120 SER B C 1 ATOM 4017 O O . SER B 1 120 ? 26.689 -6.562 34.844 1.00 29.22 ? 120 SER B O 1 ATOM 4018 C CB . SER B 1 120 ? 26.575 -4.941 31.966 1.00 29.41 ? 120 SER B CB 1 ATOM 4019 O OG . SER B 1 120 ? 27.199 -4.615 30.734 1.00 27.92 ? 120 SER B OG 1 ATOM 4020 N N . GLU B 1 121 ? 26.572 -4.320 35.050 1.00 28.07 ? 121 GLU B N 1 ATOM 4021 C CA . GLU B 1 121 ? 25.943 -4.347 36.365 1.00 24.40 ? 121 GLU B CA 1 ATOM 4022 C C . GLU B 1 121 ? 24.427 -4.434 36.228 1.00 23.63 ? 121 GLU B C 1 ATOM 4023 O O . GLU B 1 121 ? 23.815 -3.525 35.646 1.00 25.49 ? 121 GLU B O 1 ATOM 4024 C CB . GLU B 1 121 ? 26.322 -3.102 37.146 1.00 25.63 ? 121 GLU B CB 1 ATOM 4025 C CG . GLU B 1 121 ? 25.699 -2.988 38.527 1.00 27.72 ? 121 GLU B CG 1 ATOM 4026 C CD . GLU B 1 121 ? 26.339 -1.875 39.350 1.00 34.53 ? 121 GLU B CD 1 ATOM 4027 O OE1 . GLU B 1 121 ? 27.586 -1.845 39.456 1.00 39.37 ? 121 GLU B OE1 1 ATOM 4028 O OE2 . GLU B 1 121 ? 25.612 -1.023 39.878 1.00 34.16 ? 121 GLU B OE2 1 ATOM 4029 N N . PRO B 1 122 ? 23.783 -5.467 36.756 1.00 24.84 ? 122 PRO B N 1 ATOM 4030 C CA . PRO B 1 122 ? 22.322 -5.545 36.666 1.00 21.26 ? 122 PRO B CA 1 ATOM 4031 C C . PRO B 1 122 ? 21.641 -4.733 37.764 1.00 25.69 ? 122 PRO B C 1 ATOM 4032 O O . PRO B 1 122 ? 22.242 -4.363 38.772 1.00 21.88 ? 122 PRO B O 1 ATOM 4033 C CB . PRO B 1 122 ? 22.047 -7.050 36.813 1.00 20.99 ? 122 PRO B CB 1 ATOM 4034 C CG . PRO B 1 122 ? 23.177 -7.542 37.707 1.00 20.91 ? 122 PRO B CG 1 ATOM 4035 C CD . PRO B 1 122 ? 24.377 -6.676 37.377 1.00 23.64 ? 122 PRO B CD 1 ATOM 4036 N N . LEU B 1 123 ? 20.343 -4.461 37.552 1.00 20.89 ? 123 LEU B N 1 ATOM 4037 C CA . LEU B 1 123 ? 19.643 -3.495 38.401 1.00 21.84 ? 123 LEU B CA 1 ATOM 4038 C C . LEU B 1 123 ? 19.656 -3.882 39.880 1.00 22.61 ? 123 LEU B C 1 ATOM 4039 O O . LEU B 1 123 ? 19.714 -3.004 40.750 1.00 21.65 ? 123 LEU B O 1 ATOM 4040 C CB . LEU B 1 123 ? 18.198 -3.310 37.923 1.00 23.07 ? 123 LEU B CB 1 ATOM 4041 C CG . LEU B 1 123 ? 17.375 -2.236 38.641 1.00 25.71 ? 123 LEU B CG 1 ATOM 4042 C CD1 . LEU B 1 123 ? 18.046 -0.878 38.584 1.00 25.35 ? 123 LEU B CD1 1 ATOM 4043 C CD2 . LEU B 1 123 ? 15.990 -2.116 38.007 1.00 26.00 ? 123 LEU B CD2 1 ATOM 4044 N N . TRP B 1 124 ? 19.572 -5.179 40.200 1.00 22.65 ? 124 TRP B N 1 ATOM 4045 C CA . TRP B 1 124 ? 19.509 -5.518 41.619 1.00 21.45 ? 124 TRP B CA 1 ATOM 4046 C C . TRP B 1 124 ? 20.818 -5.199 42.322 1.00 20.43 ? 124 TRP B C 1 ATOM 4047 O O . TRP B 1 124 ? 20.803 -4.850 43.505 1.00 21.16 ? 124 TRP B O 1 ATOM 4048 C CB . TRP B 1 124 ? 19.118 -6.979 41.842 1.00 18.56 ? 124 TRP B CB 1 ATOM 4049 C CG . TRP B 1 124 ? 20.074 -8.061 41.435 1.00 21.21 ? 124 TRP B CG 1 ATOM 4050 C CD1 . TRP B 1 124 ? 21.055 -8.616 42.203 1.00 20.39 ? 124 TRP B CD1 1 ATOM 4051 C CD2 . TRP B 1 124 ? 20.060 -8.805 40.203 1.00 19.36 ? 124 TRP B CD2 1 ATOM 4052 N NE1 . TRP B 1 124 ? 21.686 -9.629 41.512 1.00 20.53 ? 124 TRP B NE1 1 ATOM 4053 C CE2 . TRP B 1 124 ? 21.089 -9.768 40.285 1.00 21.64 ? 124 TRP B CE2 1 ATOM 4054 C CE3 . TRP B 1 124 ? 19.288 -8.735 39.034 1.00 20.14 ? 124 TRP B CE3 1 ATOM 4055 C CZ2 . TRP B 1 124 ? 21.376 -10.657 39.239 1.00 20.82 ? 124 TRP B CZ2 1 ATOM 4056 C CZ3 . TRP B 1 124 ? 19.568 -9.620 37.991 1.00 19.40 ? 124 TRP B CZ3 1 ATOM 4057 C CH2 . TRP B 1 124 ? 20.607 -10.570 38.104 1.00 19.54 ? 124 TRP B CH2 1 ATOM 4058 N N . ILE B 1 125 ? 21.939 -5.278 41.609 1.00 19.42 ? 125 ILE B N 1 ATOM 4059 C CA . ILE B 1 125 ? 23.229 -4.945 42.215 1.00 26.86 ? 125 ILE B CA 1 ATOM 4060 C C . ILE B 1 125 ? 23.339 -3.442 42.415 1.00 26.87 ? 125 ILE B C 1 ATOM 4061 O O . ILE B 1 125 ? 23.796 -2.965 43.462 1.00 26.67 ? 125 ILE B O 1 ATOM 4062 C CB . ILE B 1 125 ? 24.378 -5.490 41.345 1.00 26.73 ? 125 ILE B CB 1 ATOM 4063 C CG1 . ILE B 1 125 ? 24.301 -7.011 41.298 1.00 26.12 ? 125 ILE B CG1 1 ATOM 4064 C CG2 . ILE B 1 125 ? 25.751 -5.006 41.873 1.00 26.64 ? 125 ILE B CG2 1 ATOM 4065 C CD1 . ILE B 1 125 ? 24.415 -7.632 42.688 1.00 25.30 ? 125 ILE B CD1 1 ATOM 4066 N N . THR B 1 126 ? 22.912 -2.674 41.417 1.00 23.20 ? 126 THR B N 1 ATOM 4067 C CA . THR B 1 126 ? 22.871 -1.227 41.575 1.00 27.40 ? 126 THR B CA 1 ATOM 4068 C C . THR B 1 126 ? 22.023 -0.834 42.777 1.00 27.48 ? 126 THR B C 1 ATOM 4069 O O . THR B 1 126 ? 22.403 0.052 43.550 1.00 28.99 ? 126 THR B O 1 ATOM 4070 C CB . THR B 1 126 ? 22.339 -0.595 40.291 1.00 23.62 ? 126 THR B CB 1 ATOM 4071 O OG1 . THR B 1 126 ? 23.181 -0.993 39.201 1.00 24.67 ? 126 THR B OG1 1 ATOM 4072 C CG2 . THR B 1 126 ? 22.347 0.926 40.398 1.00 29.59 ? 126 THR B CG2 1 ATOM 4073 N N . LEU B 1 127 ? 20.870 -1.494 42.963 1.00 27.06 ? 127 LEU B N 1 ATOM 4074 C CA . LEU B 1 127 ? 20.008 -1.181 44.098 1.00 24.10 ? 127 LEU B CA 1 ATOM 4075 C C . LEU B 1 127 ? 20.678 -1.515 45.434 1.00 27.81 ? 127 LEU B C 1 ATOM 4076 O O . LEU B 1 127 ? 20.611 -0.718 46.378 1.00 28.42 ? 127 LEU B O 1 ATOM 4077 C CB . LEU B 1 127 ? 18.661 -1.904 43.960 1.00 28.45 ? 127 LEU B CB 1 ATOM 4078 C CG . LEU B 1 127 ? 17.696 -1.252 42.956 1.00 27.72 ? 127 LEU B CG 1 ATOM 4079 C CD1 . LEU B 1 127 ? 16.722 -2.257 42.339 1.00 26.36 ? 127 LEU B CD1 1 ATOM 4080 C CD2 . LEU B 1 127 ? 16.928 -0.120 43.623 1.00 31.97 ? 127 LEU B CD2 1 ATOM 4081 N N . MET B 1 128 ? 21.331 -2.677 45.535 1.00 25.70 ? 128 MET B N 1 ATOM 4082 C CA . MET B 1 128 ? 22.058 -3.013 46.756 1.00 26.38 ? 128 MET B CA 1 ATOM 4083 C C . MET B 1 128 ? 23.142 -1.981 47.055 1.00 28.88 ? 128 MET B C 1 ATOM 4084 O O . MET B 1 128 ? 23.289 -1.538 48.198 1.00 30.34 ? 128 MET B O 1 ATOM 4085 C CB . MET B 1 128 ? 22.668 -4.409 46.643 1.00 25.84 ? 128 MET B CB 1 ATOM 4086 C CG . MET B 1 128 ? 21.642 -5.541 46.576 1.00 24.45 ? 128 MET B CG 1 ATOM 4087 S SD . MET B 1 128 ? 20.689 -5.748 48.095 1.00 28.34 ? 128 MET B SD 1 ATOM 4088 C CE . MET B 1 128 ? 22.014 -5.934 49.296 1.00 26.25 ? 128 MET B CE 1 ATOM 4089 N N . LYS B 1 129 ? 23.908 -1.575 46.037 1.00 30.66 ? 129 LYS B N 1 ATOM 4090 C CA . LYS B 1 129 ? 24.983 -0.614 46.285 1.00 34.03 ? 129 LYS B CA 1 ATOM 4091 C C . LYS B 1 129 ? 24.436 0.738 46.731 1.00 39.10 ? 129 LYS B C 1 ATOM 4092 O O . LYS B 1 129 ? 25.121 1.474 47.449 1.00 36.04 ? 129 LYS B O 1 ATOM 4093 C CB . LYS B 1 129 ? 25.866 -0.464 45.046 1.00 30.65 ? 129 LYS B CB 1 ATOM 4094 C CG . LYS B 1 129 ? 26.680 -1.708 44.746 1.00 29.43 ? 129 LYS B CG 1 ATOM 4095 C CD . LYS B 1 129 ? 27.161 -1.772 43.307 1.00 37.59 ? 129 LYS B CD 1 ATOM 4096 C CE . LYS B 1 129 ? 28.347 -0.864 43.070 1.00 43.50 ? 129 LYS B CE 1 ATOM 4097 N NZ . LYS B 1 129 ? 29.071 -1.205 41.810 1.00 44.34 ? 129 LYS B NZ 1 ATOM 4098 N N . ALA B 1 130 ? 23.204 1.069 46.343 1.00 33.28 ? 130 ALA B N 1 ATOM 4099 C CA . ALA B 1 130 ? 22.503 2.257 46.812 1.00 30.23 ? 130 ALA B CA 1 ATOM 4100 C C . ALA B 1 130 ? 21.738 2.005 48.102 1.00 33.55 ? 130 ALA B C 1 ATOM 4101 O O . ALA B 1 130 ? 20.835 2.776 48.439 1.00 37.92 ? 130 ALA B O 1 ATOM 4102 C CB . ALA B 1 130 ? 21.544 2.764 45.735 1.00 29.68 ? 130 ALA B CB 1 ATOM 4103 N N . ARG B 1 131 ? 22.059 0.924 48.809 1.00 32.02 ? 131 ARG B N 1 ATOM 4104 C CA . ARG B 1 131 ? 21.472 0.583 50.104 1.00 38.57 ? 131 ARG B CA 1 ATOM 4105 C C . ARG B 1 131 ? 19.966 0.322 50.030 1.00 38.28 ? 131 ARG B C 1 ATOM 4106 O O . ARG B 1 131 ? 19.261 0.452 51.037 1.00 35.72 ? 131 ARG B O 1 ATOM 4107 C CB . ARG B 1 131 ? 21.787 1.664 51.152 1.00 46.96 ? 131 ARG B CB 1 ATOM 4108 C CG . ARG B 1 131 ? 23.284 1.848 51.386 1.00 40.84 ? 131 ARG B CG 1 ATOM 4109 C CD . ARG B 1 131 ? 23.606 3.079 52.236 1.00 56.11 ? 131 ARG B CD 1 ATOM 4110 N NE . ARG B 1 131 ? 23.512 2.811 53.671 1.00 64.82 ? 131 ARG B NE 1 ATOM 4111 C CZ . ARG B 1 131 ? 22.568 3.303 54.469 1.00 67.30 ? 131 ARG B CZ 1 ATOM 4112 N NH1 . ARG B 1 131 ? 21.628 4.103 53.981 1.00 69.92 ? 131 ARG B NH1 1 ATOM 4113 N NH2 . ARG B 1 131 ? 22.568 3.001 55.761 1.00 70.03 ? 131 ARG B NH2 1 ATOM 4114 N N . ARG B 1 132 ? 19.446 -0.048 48.861 1.00 30.82 ? 132 ARG B N 1 ATOM 4115 C CA . ARG B 1 132 ? 18.104 -0.605 48.818 1.00 29.79 ? 132 ARG B CA 1 ATOM 4116 C C . ARG B 1 132 ? 18.173 -2.100 49.131 1.00 32.75 ? 132 ARG B C 1 ATOM 4117 O O . ARG B 1 132 ? 19.237 -2.719 49.063 1.00 35.08 ? 132 ARG B O 1 ATOM 4118 C CB . ARG B 1 132 ? 17.466 -0.365 47.448 1.00 31.41 ? 132 ARG B CB 1 ATOM 4119 C CG . ARG B 1 132 ? 17.528 1.087 46.989 1.00 34.79 ? 132 ARG B CG 1 ATOM 4120 C CD . ARG B 1 132 ? 16.462 1.943 47.648 1.00 40.77 ? 132 ARG B CD 1 ATOM 4121 N NE . ARG B 1 132 ? 16.690 3.360 47.368 1.00 49.39 ? 132 ARG B NE 1 ATOM 4122 C CZ . ARG B 1 132 ? 16.362 3.968 46.232 1.00 51.75 ? 132 ARG B CZ 1 ATOM 4123 N NH1 . ARG B 1 132 ? 15.781 3.290 45.255 1.00 53.07 ? 132 ARG B NH1 1 ATOM 4124 N NH2 . ARG B 1 132 ? 16.617 5.259 46.070 1.00 59.22 ? 132 ARG B NH2 1 ATOM 4125 N N . LYS B 1 133 ? 17.032 -2.673 49.502 1.00 27.40 ? 133 LYS B N 1 ATOM 4126 C CA . LYS B 1 133 ? 16.952 -4.076 49.890 1.00 27.52 ? 133 LYS B CA 1 ATOM 4127 C C . LYS B 1 133 ? 16.285 -4.877 48.775 1.00 28.77 ? 133 LYS B C 1 ATOM 4128 O O . LYS B 1 133 ? 15.245 -4.458 48.251 1.00 24.62 ? 133 LYS B O 1 ATOM 4129 C CB . LYS B 1 133 ? 16.184 -4.211 51.202 1.00 28.87 ? 133 LYS B CB 1 ATOM 4130 C CG . LYS B 1 133 ? 16.883 -3.484 52.353 1.00 35.03 ? 133 LYS B CG 1 ATOM 4131 C CD . LYS B 1 133 ? 15.908 -3.105 53.444 1.00 37.77 ? 133 LYS B CD 1 ATOM 4132 C CE . LYS B 1 133 ? 16.613 -2.284 54.507 1.00 48.91 ? 133 LYS B CE 1 ATOM 4133 N NZ . LYS B 1 133 ? 15.724 -2.006 55.670 1.00 58.44 ? 133 LYS B NZ 1 ATOM 4134 N N . VAL B 1 134 ? 16.886 -6.014 48.403 1.00 22.89 ? 134 VAL B N 1 ATOM 4135 C CA . VAL B 1 134 ? 16.424 -6.813 47.264 1.00 21.39 ? 134 VAL B CA 1 ATOM 4136 C C . VAL B 1 134 ? 16.231 -8.263 47.693 1.00 22.63 ? 134 VAL B C 1 ATOM 4137 O O . VAL B 1 134 ? 17.183 -8.906 48.153 1.00 23.34 ? 134 VAL B O 1 ATOM 4138 C CB . VAL B 1 134 ? 17.398 -6.756 46.074 1.00 21.23 ? 134 VAL B CB 1 ATOM 4139 C CG1 . VAL B 1 134 ? 16.799 -7.523 44.893 1.00 21.53 ? 134 VAL B CG1 1 ATOM 4140 C CG2 . VAL B 1 134 ? 17.733 -5.321 45.686 1.00 24.68 ? 134 VAL B CG2 1 ATOM 4141 N N . TYR B 1 135 ? 15.018 -8.785 47.502 1.00 18.45 ? 135 TYR B N 1 ATOM 4142 C CA . TYR B 1 135 ? 14.683 -10.195 47.700 1.00 17.62 ? 135 TYR B CA 1 ATOM 4143 C C . TYR B 1 135 ? 14.432 -10.837 46.341 1.00 23.84 ? 135 TYR B C 1 ATOM 4144 O O . TYR B 1 135 ? 13.654 -10.307 45.542 1.00 18.57 ? 135 TYR B O 1 ATOM 4145 C CB . TYR B 1 135 ? 13.422 -10.355 48.549 1.00 21.45 ? 135 TYR B CB 1 ATOM 4146 C CG . TYR B 1 135 ? 13.643 -10.319 50.047 1.00 21.88 ? 135 TYR B CG 1 ATOM 4147 C CD1 . TYR B 1 135 ? 14.479 -9.379 50.627 1.00 23.62 ? 135 TYR B CD1 1 ATOM 4148 C CD2 . TYR B 1 135 ? 12.998 -11.219 50.872 1.00 28.92 ? 135 TYR B CD2 1 ATOM 4149 C CE1 . TYR B 1 135 ? 14.671 -9.337 52.006 1.00 28.30 ? 135 TYR B CE1 1 ATOM 4150 C CE2 . TYR B 1 135 ? 13.187 -11.196 52.246 1.00 33.44 ? 135 TYR B CE2 1 ATOM 4151 C CZ . TYR B 1 135 ? 14.023 -10.256 52.805 1.00 34.18 ? 135 TYR B CZ 1 ATOM 4152 O OH . TYR B 1 135 ? 14.201 -10.247 54.171 1.00 35.85 ? 135 TYR B OH 1 ATOM 4153 N N . MET B 1 136 ? 15.066 -11.977 46.081 1.00 18.66 ? 136 MET B N 1 ATOM 4154 C CA . MET B 1 136 ? 14.925 -12.637 44.788 1.00 20.50 ? 136 MET B CA 1 ATOM 4155 C C . MET B 1 136 ? 14.541 -14.098 44.995 1.00 18.45 ? 136 MET B C 1 ATOM 4156 O O . MET B 1 136 ? 15.103 -14.779 45.861 1.00 21.66 ? 136 MET B O 1 ATOM 4157 C CB . MET B 1 136 ? 16.225 -12.506 43.976 1.00 20.75 ? 136 MET B CB 1 ATOM 4158 C CG . MET B 1 136 ? 16.671 -11.038 43.816 1.00 21.01 ? 136 MET B CG 1 ATOM 4159 S SD . MET B 1 136 ? 18.091 -10.753 42.743 1.00 23.62 ? 136 MET B SD 1 ATOM 4160 C CE . MET B 1 136 ? 17.371 -10.888 41.109 1.00 24.29 ? 136 MET B CE 1 ATOM 4161 N N . TYR B 1 137 ? 13.578 -14.570 44.210 1.00 20.51 ? 137 TYR B N 1 ATOM 4162 C CA . TYR B 1 137 ? 12.988 -15.893 44.381 1.00 20.23 ? 137 TYR B CA 1 ATOM 4163 C C . TYR B 1 137 ? 13.191 -16.674 43.090 1.00 20.60 ? 137 TYR B C 1 ATOM 4164 O O . TYR B 1 137 ? 12.564 -16.363 42.076 1.00 19.80 ? 137 TYR B O 1 ATOM 4165 C CB . TYR B 1 137 ? 11.497 -15.796 44.722 1.00 19.28 ? 137 TYR B CB 1 ATOM 4166 C CG . TYR B 1 137 ? 11.187 -15.039 45.991 1.00 19.71 ? 137 TYR B CG 1 ATOM 4167 C CD1 . TYR B 1 137 ? 11.141 -13.643 45.999 1.00 22.02 ? 137 TYR B CD1 1 ATOM 4168 C CD2 . TYR B 1 137 ? 10.910 -15.711 47.178 1.00 23.79 ? 137 TYR B CD2 1 ATOM 4169 C CE1 . TYR B 1 137 ? 10.841 -12.948 47.154 1.00 23.52 ? 137 TYR B CE1 1 ATOM 4170 C CE2 . TYR B 1 137 ? 10.600 -15.007 48.353 1.00 24.01 ? 137 TYR B CE2 1 ATOM 4171 C CZ . TYR B 1 137 ? 10.569 -13.632 48.324 1.00 26.07 ? 137 TYR B CZ 1 ATOM 4172 O OH . TYR B 1 137 ? 10.273 -12.912 49.463 1.00 24.62 ? 137 TYR B OH 1 ATOM 4173 N N . TYR B 1 138 ? 14.051 -17.692 43.136 1.00 23.08 ? 138 TYR B N 1 ATOM 4174 C CA . TYR B 1 138 ? 14.365 -18.577 42.011 1.00 18.86 ? 138 TYR B CA 1 ATOM 4175 C C . TYR B 1 138 ? 14.957 -17.845 40.808 1.00 21.92 ? 138 TYR B C 1 ATOM 4176 O O . TYR B 1 138 ? 14.996 -18.408 39.708 1.00 18.75 ? 138 TYR B O 1 ATOM 4177 C CB . TYR B 1 138 ? 13.135 -19.375 41.554 1.00 18.64 ? 138 TYR B CB 1 ATOM 4178 C CG . TYR B 1 138 ? 12.337 -20.022 42.663 1.00 23.47 ? 138 TYR B CG 1 ATOM 4179 C CD1 . TYR B 1 138 ? 12.909 -20.987 43.493 1.00 23.40 ? 138 TYR B CD1 1 ATOM 4180 C CD2 . TYR B 1 138 ? 11.010 -19.692 42.867 1.00 19.34 ? 138 TYR B CD2 1 ATOM 4181 C CE1 . TYR B 1 138 ? 12.172 -21.587 44.502 1.00 25.29 ? 138 TYR B CE1 1 ATOM 4182 C CE2 . TYR B 1 138 ? 10.261 -20.286 43.875 1.00 24.76 ? 138 TYR B CE2 1 ATOM 4183 C CZ . TYR B 1 138 ? 10.847 -21.235 44.689 1.00 27.72 ? 138 TYR B CZ 1 ATOM 4184 O OH . TYR B 1 138 ? 10.102 -21.835 45.689 1.00 25.56 ? 138 TYR B OH 1 ATOM 4185 N N . TRP B 1 139 ? 15.392 -16.598 40.970 1.00 21.19 ? 139 TRP B N 1 ATOM 4186 C CA . TRP B 1 139 ? 15.810 -15.793 39.830 1.00 21.23 ? 139 TRP B CA 1 ATOM 4187 C C . TRP B 1 139 ? 17.204 -16.210 39.376 1.00 21.65 ? 139 TRP B C 1 ATOM 4188 O O . TRP B 1 139 ? 18.162 -16.039 40.135 1.00 21.50 ? 139 TRP B O 1 ATOM 4189 C CB . TRP B 1 139 ? 15.816 -14.323 40.213 1.00 21.81 ? 139 TRP B CB 1 ATOM 4190 C CG . TRP B 1 139 ? 15.918 -13.373 39.064 1.00 22.46 ? 139 TRP B CG 1 ATOM 4191 C CD1 . TRP B 1 139 ? 17.051 -13.014 38.384 1.00 22.93 ? 139 TRP B CD1 1 ATOM 4192 C CD2 . TRP B 1 139 ? 14.847 -12.616 38.495 1.00 20.48 ? 139 TRP B CD2 1 ATOM 4193 N NE1 . TRP B 1 139 ? 16.740 -12.070 37.416 1.00 19.67 ? 139 TRP B NE1 1 ATOM 4194 C CE2 . TRP B 1 139 ? 15.395 -11.828 37.459 1.00 17.38 ? 139 TRP B CE2 1 ATOM 4195 C CE3 . TRP B 1 139 ? 13.472 -12.539 38.749 1.00 18.03 ? 139 TRP B CE3 1 ATOM 4196 C CZ2 . TRP B 1 139 ? 14.625 -10.975 36.690 1.00 19.57 ? 139 TRP B CZ2 1 ATOM 4197 C CZ3 . TRP B 1 139 ? 12.704 -11.662 37.970 1.00 17.73 ? 139 TRP B CZ3 1 ATOM 4198 C CH2 . TRP B 1 139 ? 13.286 -10.907 36.963 1.00 16.94 ? 139 TRP B CH2 1 ATOM 4199 N N . PRO B 1 140 ? 17.363 -16.748 38.168 1.00 23.99 ? 140 PRO B N 1 ATOM 4200 C CA . PRO B 1 140 ? 18.690 -17.206 37.739 1.00 25.19 ? 140 PRO B CA 1 ATOM 4201 C C . PRO B 1 140 ? 19.678 -16.054 37.738 1.00 27.08 ? 140 PRO B C 1 ATOM 4202 O O . PRO B 1 140 ? 19.457 -15.022 37.098 1.00 22.65 ? 140 PRO B O 1 ATOM 4203 C CB . PRO B 1 140 ? 18.434 -17.760 36.331 1.00 24.13 ? 140 PRO B CB 1 ATOM 4204 C CG . PRO B 1 140 ? 16.981 -18.189 36.374 1.00 30.19 ? 140 PRO B CG 1 ATOM 4205 C CD . PRO B 1 140 ? 16.329 -17.062 37.165 1.00 24.75 ? 140 PRO B CD 1 ATOM 4206 N N . GLY B 1 141 ? 20.761 -16.226 38.502 1.00 24.69 ? 141 GLY B N 1 ATOM 4207 C CA . GLY B 1 141 ? 21.725 -15.177 38.753 1.00 23.58 ? 141 GLY B CA 1 ATOM 4208 C C . GLY B 1 141 ? 21.704 -14.624 40.164 1.00 24.65 ? 141 GLY B C 1 ATOM 4209 O O . GLY B 1 141 ? 22.700 -14.017 40.588 1.00 25.94 ? 141 GLY B O 1 ATOM 4210 N N . CYS B 1 142 ? 20.610 -14.802 40.913 1.00 19.77 ? 142 CYS B N 1 ATOM 4211 C CA . CYS B 1 142 ? 20.603 -14.221 42.253 1.00 20.37 ? 142 CYS B CA 1 ATOM 4212 C C . CYS B 1 142 ? 21.587 -14.922 43.177 1.00 24.29 ? 142 CYS B C 1 ATOM 4213 O O . CYS B 1 142 ? 21.971 -14.344 44.197 1.00 22.14 ? 142 CYS B O 1 ATOM 4214 C CB . CYS B 1 142 ? 19.202 -14.236 42.883 1.00 22.96 ? 142 CYS B CB 1 ATOM 4215 S SG . CYS B 1 142 ? 18.428 -15.789 43.443 1.00 28.90 ? 142 CYS B SG 1 ATOM 4216 N N . GLU B 1 143 ? 22.018 -16.128 42.820 1.00 22.78 ? 143 GLU B N 1 ATOM 4217 C CA . GLU B 1 143 ? 22.931 -16.931 43.630 1.00 25.38 ? 143 GLU B CA 1 ATOM 4218 C C . GLU B 1 143 ? 24.401 -16.608 43.376 1.00 27.11 ? 143 GLU B C 1 ATOM 4219 O O . GLU B 1 143 ? 25.284 -17.259 43.955 1.00 23.76 ? 143 GLU B O 1 ATOM 4220 C CB . GLU B 1 143 ? 22.666 -18.416 43.372 1.00 24.29 ? 143 GLU B CB 1 ATOM 4221 C CG . GLU B 1 143 ? 23.212 -18.974 42.055 1.00 25.36 ? 143 GLU B CG 1 ATOM 4222 C CD . GLU B 1 143 ? 22.426 -18.595 40.787 1.00 38.13 ? 143 GLU B CD 1 ATOM 4223 O OE1 . GLU B 1 143 ? 21.395 -17.877 40.857 1.00 27.61 ? 143 GLU B OE1 1 ATOM 4224 O OE2 . GLU B 1 143 ? 22.859 -19.042 39.696 1.00 38.13 ? 143 GLU B OE2 1 ATOM 4225 N N . VAL B 1 144 ? 24.683 -15.613 42.544 1.00 22.78 ? 144 VAL B N 1 ATOM 4226 C CA . VAL B 1 144 ? 26.030 -15.269 42.108 1.00 23.77 ? 144 VAL B CA 1 ATOM 4227 C C . VAL B 1 144 ? 26.498 -14.019 42.849 1.00 24.30 ? 144 VAL B C 1 ATOM 4228 O O . VAL B 1 144 ? 25.716 -13.087 43.068 1.00 24.00 ? 144 VAL B O 1 ATOM 4229 C CB . VAL B 1 144 ? 26.041 -15.048 40.579 1.00 23.77 ? 144 VAL B CB 1 ATOM 4230 C CG1 . VAL B 1 144 ? 27.397 -14.634 40.080 1.00 23.70 ? 144 VAL B CG1 1 ATOM 4231 C CG2 . VAL B 1 144 ? 25.548 -16.317 39.844 1.00 22.85 ? 144 VAL B CG2 1 ATOM 4232 N N . GLU B 1 145 ? 27.778 -13.990 43.234 1.00 24.84 ? 145 GLU B N 1 ATOM 4233 C CA . GLU B 1 145 ? 28.401 -12.728 43.639 1.00 22.99 ? 145 GLU B CA 1 ATOM 4234 C C . GLU B 1 145 ? 28.754 -11.953 42.370 1.00 25.39 ? 145 GLU B C 1 ATOM 4235 O O . GLU B 1 145 ? 29.687 -12.319 41.648 1.00 24.98 ? 145 GLU B O 1 ATOM 4236 C CB . GLU B 1 145 ? 29.641 -12.965 44.509 1.00 27.89 ? 145 GLU B CB 1 ATOM 4237 C CG . GLU B 1 145 ? 30.126 -11.682 45.208 1.00 26.85 ? 145 GLU B CG 1 ATOM 4238 C CD . GLU B 1 145 ? 31.471 -11.828 45.928 1.00 37.13 ? 145 GLU B CD 1 ATOM 4239 O OE1 . GLU B 1 145 ? 31.493 -12.251 47.105 1.00 34.65 ? 145 GLU B OE1 1 ATOM 4240 O OE2 . GLU B 1 145 ? 32.513 -11.506 45.314 1.00 34.83 ? 145 GLU B OE2 1 ATOM 4241 N N . ILE B 1 146 ? 27.997 -10.900 42.069 1.00 23.03 ? 146 ILE B N 1 ATOM 4242 C CA . ILE B 1 146 ? 28.195 -10.121 40.846 1.00 23.93 ? 146 ILE B CA 1 ATOM 4243 C C . ILE B 1 146 ? 28.835 -8.798 41.224 1.00 25.04 ? 146 ILE B C 1 ATOM 4244 O O . ILE B 1 146 ? 28.262 -8.027 42.005 1.00 25.76 ? 146 ILE B O 1 ATOM 4245 C CB . ILE B 1 146 ? 26.880 -9.882 40.084 1.00 23.13 ? 146 ILE B CB 1 ATOM 4246 C CG1 . ILE B 1 146 ? 26.211 -11.204 39.707 1.00 22.33 ? 146 ILE B CG1 1 ATOM 4247 C CG2 . ILE B 1 146 ? 27.165 -9.057 38.819 1.00 22.41 ? 146 ILE B CG2 1 ATOM 4248 C CD1 . ILE B 1 146 ? 24.818 -11.028 39.083 1.00 23.40 ? 146 ILE B CD1 1 ATOM 4249 N N . LEU B 1 147 ? 30.010 -8.525 40.652 1.00 25.49 ? 147 LEU B N 1 ATOM 4250 C CA . LEU B 1 147 ? 30.753 -7.290 40.928 1.00 26.80 ? 147 LEU B CA 1 ATOM 4251 C C . LEU B 1 147 ? 30.932 -7.083 42.433 1.00 27.58 ? 147 LEU B C 1 ATOM 4252 O O . LEU B 1 147 ? 30.839 -5.966 42.950 1.00 34.12 ? 147 LEU B O 1 ATOM 4253 C CB . LEU B 1 147 ? 30.070 -6.082 40.267 1.00 27.13 ? 147 LEU B CB 1 ATOM 4254 C CG . LEU B 1 147 ? 29.963 -6.142 38.735 1.00 27.08 ? 147 LEU B CG 1 ATOM 4255 C CD1 . LEU B 1 147 ? 28.988 -5.087 38.173 1.00 27.19 ? 147 LEU B CD1 1 ATOM 4256 C CD2 . LEU B 1 147 ? 31.337 -5.979 38.087 1.00 32.73 ? 147 LEU B CD2 1 ATOM 4257 N N . GLY B 1 148 ? 31.169 -8.186 43.147 1.00 29.80 ? 148 GLY B N 1 ATOM 4258 C CA . GLY B 1 148 ? 31.406 -8.175 44.580 1.00 30.55 ? 148 GLY B CA 1 ATOM 4259 C C . GLY B 1 148 ? 30.178 -8.075 45.460 1.00 32.63 ? 148 GLY B C 1 ATOM 4260 O O . GLY B 1 148 ? 30.332 -7.982 46.684 1.00 28.18 ? 148 GLY B O 1 ATOM 4261 N N . VAL B 1 149 ? 28.965 -8.117 44.885 1.00 24.29 ? 149 VAL B N 1 ATOM 4262 C CA . VAL B 1 149 ? 27.722 -7.820 45.595 1.00 25.19 ? 149 VAL B CA 1 ATOM 4263 C C . VAL B 1 149 ? 26.726 -8.968 45.434 1.00 22.76 ? 149 VAL B C 1 ATOM 4264 O O . VAL B 1 149 ? 26.738 -9.689 44.433 1.00 23.09 ? 149 VAL B O 1 ATOM 4265 C CB . VAL B 1 149 ? 27.100 -6.492 45.087 1.00 25.52 ? 149 VAL B CB 1 ATOM 4266 C CG1 . VAL B 1 149 ? 25.906 -6.065 45.955 1.00 25.54 ? 149 VAL B CG1 1 ATOM 4267 C CG2 . VAL B 1 149 ? 28.150 -5.388 45.043 1.00 27.34 ? 149 VAL B CG2 1 ATOM 4268 N N . ARG B 1 150 ? 25.854 -9.129 46.432 1.00 22.09 ? 150 ARG B N 1 ATOM 4269 C CA . ARG B 1 150 ? 24.775 -10.107 46.421 1.00 27.49 ? 150 ARG B CA 1 ATOM 4270 C C . ARG B 1 150 ? 23.488 -9.452 46.893 1.00 24.52 ? 150 ARG B C 1 ATOM 4271 O O . ARG B 1 150 ? 23.531 -8.480 47.651 1.00 23.32 ? 150 ARG B O 1 ATOM 4272 C CB . ARG B 1 150 ? 25.069 -11.305 47.336 1.00 23.14 ? 150 ARG B CB 1 ATOM 4273 C CG . ARG B 1 150 ? 26.290 -12.123 46.937 1.00 20.46 ? 150 ARG B CG 1 ATOM 4274 C CD . ARG B 1 150 ? 26.475 -13.278 47.912 1.00 23.19 ? 150 ARG B CD 1 ATOM 4275 N NE . ARG B 1 150 ? 27.557 -14.175 47.520 1.00 24.45 ? 150 ARG B NE 1 ATOM 4276 C CZ . ARG B 1 150 ? 27.379 -15.240 46.747 1.00 25.94 ? 150 ARG B CZ 1 ATOM 4277 N NH1 . ARG B 1 150 ? 26.166 -15.518 46.292 1.00 27.35 ? 150 ARG B NH1 1 ATOM 4278 N NH2 . ARG B 1 150 ? 28.406 -16.022 46.426 1.00 26.64 ? 150 ARG B NH2 1 ATOM 4279 N N . PRO B 1 151 ? 22.333 -9.978 46.486 1.00 22.77 ? 151 PRO B N 1 ATOM 4280 C CA . PRO B 1 151 ? 21.062 -9.445 46.997 1.00 22.82 ? 151 PRO B CA 1 ATOM 4281 C C . PRO B 1 151 ? 20.872 -9.760 48.474 1.00 23.14 ? 151 PRO B C 1 ATOM 4282 O O . PRO B 1 151 ? 21.444 -10.713 49.014 1.00 23.38 ? 151 PRO B O 1 ATOM 4283 C CB . PRO B 1 151 ? 20.009 -10.164 46.144 1.00 21.77 ? 151 PRO B CB 1 ATOM 4284 C CG . PRO B 1 151 ? 20.684 -11.485 45.750 1.00 21.07 ? 151 PRO B CG 1 ATOM 4285 C CD . PRO B 1 151 ? 22.126 -11.080 45.520 1.00 21.58 ? 151 PRO B CD 1 ATOM 4286 N N . THR B 1 152 ? 20.011 -8.961 49.117 1.00 23.56 ? 152 THR B N 1 ATOM 4287 C CA . THR B 1 152 ? 19.649 -9.198 50.517 1.00 23.53 ? 152 THR B CA 1 ATOM 4288 C C . THR B 1 152 ? 19.216 -10.636 50.742 1.00 27.90 ? 152 THR B C 1 ATOM 4289 O O . THR B 1 152 ? 19.595 -11.267 51.739 1.00 22.73 ? 152 THR B O 1 ATOM 4290 C CB . THR B 1 152 ? 18.519 -8.259 50.939 1.00 23.75 ? 152 THR B CB 1 ATOM 4291 O OG1 . THR B 1 152 ? 18.892 -6.906 50.663 1.00 25.54 ? 152 THR B OG1 1 ATOM 4292 C CG2 . THR B 1 152 ? 18.197 -8.430 52.426 1.00 27.90 ? 152 THR B CG2 1 ATOM 4293 N N . TYR B 1 153 ? 18.408 -11.168 49.830 1.00 24.07 ? 153 TYR B N 1 ATOM 4294 C CA . TYR B 1 153 ? 17.882 -12.511 49.973 1.00 23.46 ? 153 TYR B CA 1 ATOM 4295 C C . TYR B 1 153 ? 17.791 -13.133 48.593 1.00 24.34 ? 153 TYR B C 1 ATOM 4296 O O . TYR B 1 153 ? 17.344 -12.483 47.644 1.00 20.06 ? 153 TYR B O 1 ATOM 4297 C CB . TYR B 1 153 ? 16.509 -12.499 50.641 1.00 23.63 ? 153 TYR B CB 1 ATOM 4298 C CG . TYR B 1 153 ? 15.794 -13.830 50.656 1.00 25.09 ? 153 TYR B CG 1 ATOM 4299 C CD1 . TYR B 1 153 ? 16.085 -14.798 51.617 1.00 22.55 ? 153 TYR B CD1 1 ATOM 4300 C CD2 . TYR B 1 153 ? 14.807 -14.109 49.727 1.00 22.71 ? 153 TYR B CD2 1 ATOM 4301 C CE1 . TYR B 1 153 ? 15.405 -16.018 51.634 1.00 27.41 ? 153 TYR B CE1 1 ATOM 4302 C CE2 . TYR B 1 153 ? 14.121 -15.310 49.739 1.00 25.89 ? 153 TYR B CE2 1 ATOM 4303 C CZ . TYR B 1 153 ? 14.422 -16.261 50.685 1.00 26.33 ? 153 TYR B CZ 1 ATOM 4304 O OH . TYR B 1 153 ? 13.723 -17.446 50.668 1.00 28.87 ? 153 TYR B OH 1 ATOM 4305 N N . CYS B 1 154 ? 18.225 -14.384 48.492 1.00 24.73 ? 154 CYS B N 1 ATOM 4306 C CA . CYS B 1 154 ? 18.097 -15.169 47.270 1.00 19.95 ? 154 CYS B CA 1 ATOM 4307 C C . CYS B 1 154 ? 17.591 -16.549 47.646 1.00 27.95 ? 154 CYS B C 1 ATOM 4308 O O . CYS B 1 154 ? 18.206 -17.231 48.472 1.00 28.23 ? 154 CYS B O 1 ATOM 4309 C CB . CYS B 1 154 ? 19.433 -15.261 46.514 1.00 26.18 ? 154 CYS B CB 1 ATOM 4310 S SG . CYS B 1 154 ? 19.544 -16.481 45.077 1.00 35.11 ? 154 CYS B SG 1 ATOM 4311 N N . LEU B 1 155 ? 16.457 -16.942 47.068 1.00 22.17 ? 155 LEU B N 1 ATOM 4312 C CA . LEU B 1 155 ? 15.973 -18.316 47.120 1.00 23.72 ? 155 LEU B CA 1 ATOM 4313 C C . LEU B 1 155 ? 16.443 -18.958 45.821 1.00 25.84 ? 155 LEU B C 1 ATOM 4314 O O . LEU B 1 155 ? 15.882 -18.701 44.755 1.00 22.74 ? 155 LEU B O 1 ATOM 4315 C CB . LEU B 1 155 ? 14.458 -18.363 47.283 1.00 19.91 ? 155 LEU B CB 1 ATOM 4316 C CG . LEU B 1 155 ? 13.823 -19.753 47.338 1.00 26.83 ? 155 LEU B CG 1 ATOM 4317 C CD1 . LEU B 1 155 ? 14.363 -20.526 48.547 1.00 28.23 ? 155 LEU B CD1 1 ATOM 4318 C CD2 . LEU B 1 155 ? 12.300 -19.644 47.379 1.00 24.59 ? 155 LEU B CD2 1 ATOM 4319 N N . GLU B 1 156 ? 17.503 -19.765 45.910 1.00 20.34 ? 156 GLU B N 1 ATOM 4320 C CA . GLU B 1 156 ? 18.230 -20.184 44.719 1.00 22.45 ? 156 GLU B CA 1 ATOM 4321 C C . GLU B 1 156 ? 17.395 -21.098 43.819 1.00 24.66 ? 156 GLU B C 1 ATOM 4322 O O . GLU B 1 156 ? 16.653 -21.962 44.295 1.00 24.55 ? 156 GLU B O 1 ATOM 4323 C CB . GLU B 1 156 ? 19.520 -20.904 45.126 1.00 26.90 ? 156 GLU B CB 1 ATOM 4324 C CG . GLU B 1 156 ? 20.417 -21.204 43.934 1.00 37.36 ? 156 GLU B CG 1 ATOM 4325 C CD . GLU B 1 156 ? 21.755 -21.818 44.323 1.00 42.65 ? 156 GLU B CD 1 ATOM 4326 O OE1 . GLU B 1 156 ? 22.352 -21.381 45.330 1.00 45.66 ? 156 GLU B OE1 1 ATOM 4327 O OE2 . GLU B 1 156 ? 22.211 -22.736 43.613 1.00 44.09 ? 156 GLU B OE2 1 ATOM 4328 N N . TYR B 1 157 ? 17.540 -20.922 42.503 1.00 24.54 ? 157 TYR B N 1 ATOM 4329 C CA . TYR B 1 157 ? 16.939 -21.861 41.562 1.00 24.91 ? 157 TYR B CA 1 ATOM 4330 C C . TYR B 1 157 ? 17.642 -23.207 41.689 1.00 27.88 ? 157 TYR B C 1 ATOM 4331 O O . TYR B 1 157 ? 18.869 -23.277 41.610 1.00 31.02 ? 157 TYR B O 1 ATOM 4332 C CB . TYR B 1 157 ? 17.045 -21.355 40.120 1.00 26.23 ? 157 TYR B CB 1 ATOM 4333 C CG . TYR B 1 157 ? 16.455 -22.302 39.082 1.00 27.83 ? 157 TYR B CG 1 ATOM 4334 C CD1 . TYR B 1 157 ? 17.187 -23.387 38.614 1.00 29.31 ? 157 TYR B CD1 1 ATOM 4335 C CD2 . TYR B 1 157 ? 15.177 -22.104 38.560 1.00 22.55 ? 157 TYR B CD2 1 ATOM 4336 C CE1 . TYR B 1 157 ? 16.668 -24.262 37.687 1.00 31.03 ? 157 TYR B CE1 1 ATOM 4337 C CE2 . TYR B 1 157 ? 14.642 -22.991 37.611 1.00 24.14 ? 157 TYR B CE2 1 ATOM 4338 C CZ . TYR B 1 157 ? 15.409 -24.066 37.178 1.00 31.01 ? 157 TYR B CZ 1 ATOM 4339 O OH . TYR B 1 157 ? 14.915 -24.956 36.240 1.00 26.98 ? 157 TYR B OH 1 ATOM 4340 N N . LYS B 1 158 ? 16.857 -24.273 41.862 1.00 25.91 ? 158 LYS B N 1 ATOM 4341 C CA . LYS B 1 158 ? 17.388 -25.636 41.861 1.00 32.26 ? 158 LYS B CA 1 ATOM 4342 C C . LYS B 1 158 ? 16.709 -26.476 40.790 1.00 33.35 ? 158 LYS B C 1 ATOM 4343 O O . LYS B 1 158 ? 17.361 -26.883 39.830 1.00 34.95 ? 158 LYS B O 1 ATOM 4344 C CB . LYS B 1 158 ? 17.232 -26.254 43.250 1.00 35.90 ? 158 LYS B CB 1 ATOM 4345 C CG . LYS B 1 158 ? 18.080 -25.552 44.297 1.00 38.21 ? 158 LYS B CG 1 ATOM 4346 C CD . LYS B 1 158 ? 17.869 -26.121 45.680 1.00 41.55 ? 158 LYS B CD 1 ATOM 4347 C CE . LYS B 1 158 ? 18.836 -25.472 46.653 1.00 47.82 ? 158 LYS B CE 1 ATOM 4348 N NZ . LYS B 1 158 ? 20.246 -25.606 46.173 1.00 57.59 ? 158 LYS B NZ 1 ATOM 4349 N N . THR B 1 159 ? 15.422 -26.747 40.921 1.00 33.20 ? 159 THR B N 1 ATOM 4350 C CA . THR B 1 159 ? 14.647 -27.456 39.922 1.00 36.13 ? 159 THR B CA 1 ATOM 4351 C C . THR B 1 159 ? 13.553 -26.528 39.417 1.00 32.47 ? 159 THR B C 1 ATOM 4352 O O . THR B 1 159 ? 13.415 -25.395 39.886 1.00 31.81 ? 159 THR B O 1 ATOM 4353 C CB . THR B 1 159 ? 14.054 -28.739 40.509 1.00 36.51 ? 159 THR B CB 1 ATOM 4354 O OG1 . THR B 1 159 ? 13.134 -28.401 41.557 1.00 36.96 ? 159 THR B OG1 1 ATOM 4355 C CG2 . THR B 1 159 ? 15.168 -29.596 41.096 1.00 43.06 ? 159 THR B CG2 1 ATOM 4356 N N . VAL B 1 160 ? 12.774 -27.008 38.451 1.00 28.12 ? 160 VAL B N 1 ATOM 4357 C CA . VAL B 1 160 ? 11.667 -26.225 37.898 1.00 27.34 ? 160 VAL B CA 1 ATOM 4358 C C . VAL B 1 160 ? 10.702 -25.912 39.035 1.00 30.20 ? 160 VAL B C 1 ATOM 4359 O O . VAL B 1 160 ? 10.198 -26.841 39.682 1.00 28.34 ? 160 VAL B O 1 ATOM 4360 C CB . VAL B 1 160 ? 10.949 -26.977 36.763 1.00 29.33 ? 160 VAL B CB 1 ATOM 4361 C CG1 . VAL B 1 160 ? 9.717 -26.202 36.316 1.00 29.39 ? 160 VAL B CG1 1 ATOM 4362 C CG2 . VAL B 1 160 ? 11.887 -27.204 35.595 1.00 30.19 ? 160 VAL B CG2 1 ATOM 4363 N N . PRO B 1 161 ? 10.440 -24.640 39.341 1.00 26.12 ? 161 PRO B N 1 ATOM 4364 C CA . PRO B 1 161 ? 9.509 -24.339 40.434 1.00 23.88 ? 161 PRO B CA 1 ATOM 4365 C C . PRO B 1 161 ? 8.096 -24.770 40.071 1.00 30.16 ? 161 PRO B C 1 ATOM 4366 O O . PRO B 1 161 ? 7.673 -24.679 38.916 1.00 26.89 ? 161 PRO B O 1 ATOM 4367 C CB . PRO B 1 161 ? 9.624 -22.812 40.592 1.00 24.41 ? 161 PRO B CB 1 ATOM 4368 C CG . PRO B 1 161 ? 11.001 -22.483 40.067 1.00 24.78 ? 161 PRO B CG 1 ATOM 4369 C CD . PRO B 1 161 ? 11.192 -23.448 38.904 1.00 25.23 ? 161 PRO B CD 1 ATOM 4370 N N . THR B 1 162 ? 7.357 -25.229 41.076 1.00 29.65 ? 162 THR B N 1 ATOM 4371 C CA . THR B 1 162 ? 5.979 -25.643 40.874 1.00 28.63 ? 162 THR B CA 1 ATOM 4372 C C . THR B 1 162 ? 5.047 -24.435 40.935 1.00 27.05 ? 162 THR B C 1 ATOM 4373 O O . THR B 1 162 ? 5.427 -23.344 41.363 1.00 25.84 ? 162 THR B O 1 ATOM 4374 C CB . THR B 1 162 ? 5.572 -26.684 41.918 1.00 32.64 ? 162 THR B CB 1 ATOM 4375 O OG1 . THR B 1 162 ? 5.423 -26.045 43.190 1.00 28.92 ? 162 THR B OG1 1 ATOM 4376 C CG2 . THR B 1 162 ? 6.634 -27.786 42.028 1.00 29.80 ? 162 THR B CG2 1 ATOM 4377 N N . ASP B 1 163 ? 3.800 -24.643 40.501 1.00 25.22 ? 163 ASP B N 1 ATOM 4378 C CA . ASP B 1 163 ? 2.805 -23.582 40.621 1.00 27.19 ? 163 ASP B CA 1 ATOM 4379 C C . ASP B 1 163 ? 2.543 -23.231 42.080 1.00 29.78 ? 163 ASP B C 1 ATOM 4380 O O . ASP B 1 163 ? 2.209 -22.080 42.396 1.00 25.58 ? 163 ASP B O 1 ATOM 4381 C CB . ASP B 1 163 ? 1.502 -23.986 39.926 1.00 32.50 ? 163 ASP B CB 1 ATOM 4382 C CG . ASP B 1 163 ? 1.700 -24.331 38.453 1.00 33.30 ? 163 ASP B CG 1 ATOM 4383 O OD1 . ASP B 1 163 ? 2.714 -23.907 37.850 1.00 33.74 ? 163 ASP B OD1 1 ATOM 4384 O OD2 . ASP B 1 163 ? 0.830 -25.028 37.896 1.00 32.17 ? 163 ASP B OD2 1 ATOM 4385 N N . ILE B 1 164 ? 2.698 -24.200 42.989 1.00 30.86 ? 164 ILE B N 1 ATOM 4386 C CA . ILE B 1 164 ? 2.603 -23.884 44.410 1.00 26.92 ? 164 ILE B CA 1 ATOM 4387 C C . ILE B 1 164 ? 3.816 -23.073 44.856 1.00 23.85 ? 164 ILE B C 1 ATOM 4388 O O . ILE B 1 164 ? 3.682 -22.102 45.614 1.00 27.14 ? 164 ILE B O 1 ATOM 4389 C CB . ILE B 1 164 ? 2.436 -25.175 45.235 1.00 30.21 ? 164 ILE B CB 1 ATOM 4390 C CG1 . ILE B 1 164 ? 1.042 -25.766 45.023 1.00 35.80 ? 164 ILE B CG1 1 ATOM 4391 C CG2 . ILE B 1 164 ? 2.666 -24.904 46.719 1.00 34.61 ? 164 ILE B CG2 1 ATOM 4392 C CD1 . ILE B 1 164 ? 0.847 -27.118 45.731 1.00 39.02 ? 164 ILE B CD1 1 ATOM 4393 N N . ASN B 1 165 ? 5.014 -23.446 44.388 1.00 22.78 ? 165 ASN B N 1 ATOM 4394 C CA . ASN B 1 165 ? 6.203 -22.640 44.665 1.00 24.96 ? 165 ASN B CA 1 ATOM 4395 C C . ASN B 1 165 ? 5.987 -21.194 44.238 1.00 25.02 ? 165 ASN B C 1 ATOM 4396 O O . ASN B 1 165 ? 6.379 -20.257 44.942 1.00 24.06 ? 165 ASN B O 1 ATOM 4397 C CB . ASN B 1 165 ? 7.430 -23.178 43.929 1.00 23.01 ? 165 ASN B CB 1 ATOM 4398 C CG . ASN B 1 165 ? 7.955 -24.505 44.484 1.00 31.24 ? 165 ASN B CG 1 ATOM 4399 O OD1 . ASN B 1 165 ? 8.555 -25.281 43.744 1.00 28.78 ? 165 ASN B OD1 1 ATOM 4400 N ND2 . ASN B 1 165 ? 7.759 -24.751 45.774 1.00 30.37 ? 165 ASN B ND2 1 ATOM 4401 N N . PHE B 1 166 ? 5.401 -21.004 43.054 1.00 22.83 ? 166 PHE B N 1 ATOM 4402 C CA . PHE B 1 166 ? 5.181 -19.654 42.532 1.00 21.33 ? 166 PHE B CA 1 ATOM 4403 C C . PHE B 1 166 ? 4.239 -18.870 43.429 1.00 22.58 ? 166 PHE B C 1 ATOM 4404 O O . PHE B 1 166 ? 4.532 -17.734 43.811 1.00 23.15 ? 166 PHE B O 1 ATOM 4405 C CB . PHE B 1 166 ? 4.633 -19.730 41.107 1.00 20.87 ? 166 PHE B CB 1 ATOM 4406 C CG . PHE B 1 166 ? 4.438 -18.380 40.457 1.00 21.70 ? 166 PHE B CG 1 ATOM 4407 C CD1 . PHE B 1 166 ? 5.443 -17.420 40.507 1.00 21.17 ? 166 PHE B CD1 1 ATOM 4408 C CD2 . PHE B 1 166 ? 3.270 -18.086 39.788 1.00 27.87 ? 166 PHE B CD2 1 ATOM 4409 C CE1 . PHE B 1 166 ? 5.261 -16.162 39.900 1.00 24.18 ? 166 PHE B CE1 1 ATOM 4410 C CE2 . PHE B 1 166 ? 3.088 -16.841 39.178 1.00 28.54 ? 166 PHE B CE2 1 ATOM 4411 C CZ . PHE B 1 166 ? 4.102 -15.883 39.242 1.00 20.10 ? 166 PHE B CZ 1 ATOM 4412 N N . ALA B 1 167 ? 3.094 -19.464 43.780 1.00 25.07 ? 167 ALA B N 1 ATOM 4413 C CA . ALA B 1 167 ? 2.123 -18.763 44.614 1.00 24.89 ? 167 ALA B CA 1 ATOM 4414 C C . ALA B 1 167 ? 2.701 -18.420 45.984 1.00 21.63 ? 167 ALA B C 1 ATOM 4415 O O . ALA B 1 167 ? 2.484 -17.317 46.502 1.00 24.00 ? 167 ALA B O 1 ATOM 4416 C CB . ALA B 1 167 ? 0.857 -19.608 44.763 1.00 27.47 ? 167 ALA B CB 1 ATOM 4417 N N . ASN B 1 168 ? 3.430 -19.360 46.593 1.00 22.19 ? 168 ASN B N 1 ATOM 4418 C CA . ASN B 1 168 ? 4.088 -19.091 47.869 1.00 25.19 ? 168 ASN B CA 1 ATOM 4419 C C . ASN B 1 168 ? 5.138 -17.984 47.751 1.00 26.71 ? 168 ASN B C 1 ATOM 4420 O O . ASN B 1 168 ? 5.292 -17.169 48.668 1.00 26.33 ? 168 ASN B O 1 ATOM 4421 C CB . ASN B 1 168 ? 4.720 -20.376 48.397 1.00 29.44 ? 168 ASN B CB 1 ATOM 4422 C CG . ASN B 1 168 ? 3.687 -21.351 48.937 1.00 30.37 ? 168 ASN B CG 1 ATOM 4423 O OD1 . ASN B 1 168 ? 2.620 -20.945 49.397 1.00 34.23 ? 168 ASN B OD1 1 ATOM 4424 N ND2 . ASN B 1 168 ? 4.000 -22.639 48.886 1.00 30.52 ? 168 ASN B ND2 1 ATOM 4425 N N . ALA B 1 169 ? 5.883 -17.946 46.640 1.00 22.76 ? 169 ALA B N 1 ATOM 4426 C CA . ALA B 1 169 ? 6.851 -16.871 46.441 1.00 21.72 ? 169 ALA B CA 1 ATOM 4427 C C . ALA B 1 169 ? 6.156 -15.521 46.323 1.00 22.08 ? 169 ALA B C 1 ATOM 4428 O O . ALA B 1 169 ? 6.606 -14.531 46.912 1.00 24.85 ? 169 ALA B O 1 ATOM 4429 C CB . ALA B 1 169 ? 7.708 -17.148 45.202 1.00 22.91 ? 169 ALA B CB 1 ATOM 4430 N N . VAL B 1 170 ? 5.055 -15.459 45.568 1.00 21.17 ? 170 VAL B N 1 ATOM 4431 C CA . VAL B 1 170 ? 4.319 -14.205 45.467 1.00 21.75 ? 170 VAL B CA 1 ATOM 4432 C C . VAL B 1 170 ? 3.852 -13.762 46.844 1.00 22.50 ? 170 VAL B C 1 ATOM 4433 O O . VAL B 1 170 ? 4.003 -12.594 47.222 1.00 19.37 ? 170 VAL B O 1 ATOM 4434 C CB . VAL B 1 170 ? 3.145 -14.342 44.487 1.00 23.97 ? 170 VAL B CB 1 ATOM 4435 C CG1 . VAL B 1 170 ? 2.259 -13.106 44.569 1.00 21.42 ? 170 VAL B CG1 1 ATOM 4436 C CG2 . VAL B 1 170 ? 3.675 -14.546 43.064 1.00 20.33 ? 170 VAL B CG2 1 ATOM 4437 N N . SER B 1 171 ? 3.318 -14.699 47.635 1.00 26.72 ? 171 SER B N 1 ATOM 4438 C CA . SER B 1 171 ? 2.840 -14.332 48.969 1.00 26.89 ? 171 SER B CA 1 ATOM 4439 C C . SER B 1 171 ? 3.982 -13.873 49.861 1.00 25.62 ? 171 SER B C 1 ATOM 4440 O O . SER B 1 171 ? 3.866 -12.850 50.547 1.00 27.04 ? 171 SER B O 1 ATOM 4441 C CB . SER B 1 171 ? 2.110 -15.503 49.621 1.00 30.57 ? 171 SER B CB 1 ATOM 4442 O OG . SER B 1 171 ? 1.609 -15.104 50.887 1.00 30.15 ? 171 SER B OG 1 ATOM 4443 N N . ASP B 1 172 ? 5.084 -14.629 49.887 1.00 24.86 ? 172 ASP B N 1 ATOM 4444 C CA . ASP B 1 172 ? 6.227 -14.243 50.709 1.00 23.87 ? 172 ASP B CA 1 ATOM 4445 C C . ASP B 1 172 ? 6.818 -12.909 50.262 1.00 25.24 ? 172 ASP B C 1 ATOM 4446 O O . ASP B 1 172 ? 7.198 -12.085 51.103 1.00 27.69 ? 172 ASP B O 1 ATOM 4447 C CB . ASP B 1 172 ? 7.285 -15.345 50.673 1.00 30.09 ? 172 ASP B CB 1 ATOM 4448 C CG . ASP B 1 172 ? 6.778 -16.664 51.255 1.00 39.10 ? 172 ASP B CG 1 ATOM 4449 O OD1 . ASP B 1 172 ? 5.794 -16.648 52.031 1.00 43.15 ? 172 ASP B OD1 1 ATOM 4450 O OD2 . ASP B 1 172 ? 7.358 -17.724 50.928 1.00 38.47 ? 172 ASP B OD2 1 ATOM 4451 N N . ALA B 1 173 ? 6.909 -12.678 48.945 1.00 23.89 ? 173 ALA B N 1 ATOM 4452 C CA . ALA B 1 173 ? 7.422 -11.403 48.448 1.00 22.97 ? 173 ALA B CA 1 ATOM 4453 C C . ALA B 1 173 ? 6.553 -10.243 48.902 1.00 26.07 ? 173 ALA B C 1 ATOM 4454 O O . ALA B 1 173 ? 7.073 -9.217 49.356 1.00 23.82 ? 173 ALA B O 1 ATOM 4455 C CB . ALA B 1 173 ? 7.521 -11.415 46.923 1.00 21.84 ? 173 ALA B CB 1 ATOM 4456 N N . LEU B 1 174 ? 5.226 -10.376 48.774 1.00 25.15 ? 174 LEU B N 1 ATOM 4457 C CA . LEU B 1 174 ? 4.358 -9.295 49.224 1.00 25.76 ? 174 LEU B CA 1 ATOM 4458 C C . LEU B 1 174 ? 4.551 -9.032 50.715 1.00 29.80 ? 174 LEU B C 1 ATOM 4459 O O . LEU B 1 174 ? 4.647 -7.875 51.135 1.00 30.44 ? 174 LEU B O 1 ATOM 4460 C CB . LEU B 1 174 ? 2.899 -9.608 48.896 1.00 23.35 ? 174 LEU B CB 1 ATOM 4461 C CG . LEU B 1 174 ? 2.536 -9.635 47.408 1.00 26.00 ? 174 LEU B CG 1 ATOM 4462 C CD1 . LEU B 1 174 ? 1.056 -9.977 47.220 1.00 26.50 ? 174 LEU B CD1 1 ATOM 4463 C CD2 . LEU B 1 174 ? 2.870 -8.304 46.738 1.00 26.41 ? 174 LEU B CD2 1 ATOM 4464 N N . ASP B 1 175 ? 4.669 -10.092 51.523 1.00 30.39 ? 175 ASP B N 1 ATOM 4465 C CA . ASP B 1 175 ? 4.946 -9.892 52.946 1.00 32.63 ? 175 ASP B CA 1 ATOM 4466 C C . ASP B 1 175 ? 6.259 -9.137 53.156 1.00 32.40 ? 175 ASP B C 1 ATOM 4467 O O . ASP B 1 175 ? 6.324 -8.201 53.962 1.00 33.98 ? 175 ASP B O 1 ATOM 4468 C CB . ASP B 1 175 ? 4.968 -11.239 53.679 1.00 34.25 ? 175 ASP B CB 1 ATOM 4469 C CG . ASP B 1 175 ? 3.586 -11.877 53.788 1.00 37.92 ? 175 ASP B CG 1 ATOM 4470 O OD1 . ASP B 1 175 ? 2.577 -11.160 53.621 1.00 40.52 ? 175 ASP B OD1 1 ATOM 4471 O OD2 . ASP B 1 175 ? 3.504 -13.100 54.038 1.00 43.05 ? 175 ASP B OD2 1 ATOM 4472 N N . SER B 1 176 ? 7.310 -9.499 52.412 1.00 29.56 ? 176 SER B N 1 ATOM 4473 C CA A SER B 1 176 ? 8.603 -8.851 52.605 0.50 31.63 ? 176 SER B CA 1 ATOM 4474 C CA B SER B 1 176 ? 8.604 -8.851 52.606 0.50 31.63 ? 176 SER B CA 1 ATOM 4475 C C . SER B 1 176 ? 8.578 -7.395 52.162 1.00 31.85 ? 176 SER B C 1 ATOM 4476 O O . SER B 1 176 ? 9.246 -6.554 52.769 1.00 31.21 ? 176 SER B O 1 ATOM 4477 C CB A SER B 1 176 ? 9.688 -9.625 51.858 0.50 28.74 ? 176 SER B CB 1 ATOM 4478 C CB B SER B 1 176 ? 9.704 -9.618 51.866 0.50 28.74 ? 176 SER B CB 1 ATOM 4479 O OG A SER B 1 176 ? 9.628 -10.998 52.197 0.50 24.81 ? 176 SER B OG 1 ATOM 4480 O OG B SER B 1 176 ? 9.644 -9.398 50.468 0.50 32.33 ? 176 SER B OG 1 ATOM 4481 N N . LEU B 1 177 ? 7.811 -7.078 51.118 1.00 29.28 ? 177 LEU B N 1 ATOM 4482 C CA . LEU B 1 177 ? 7.671 -5.692 50.687 1.00 29.51 ? 177 LEU B CA 1 ATOM 4483 C C . LEU B 1 177 ? 6.851 -4.890 51.690 1.00 35.37 ? 177 LEU B C 1 ATOM 4484 O O . LEU B 1 177 ? 7.194 -3.744 52.009 1.00 34.22 ? 177 LEU B O 1 ATOM 4485 C CB . LEU B 1 177 ? 7.016 -5.650 49.305 1.00 26.14 ? 177 LEU B CB 1 ATOM 4486 C CG . LEU B 1 177 ? 7.877 -6.214 48.168 1.00 24.92 ? 177 LEU B CG 1 ATOM 4487 C CD1 . LEU B 1 177 ? 7.043 -6.499 46.915 1.00 23.43 ? 177 LEU B CD1 1 ATOM 4488 C CD2 . LEU B 1 177 ? 9.018 -5.256 47.855 1.00 23.32 ? 177 LEU B CD2 1 ATOM 4489 N N . LYS B 1 178 ? 5.763 -5.481 52.191 1.00 31.26 ? 178 LYS B N 1 ATOM 4490 C CA . LYS B 1 178 ? 4.900 -4.790 53.146 1.00 40.39 ? 178 LYS B CA 1 ATOM 4491 C C . LYS B 1 178 ? 5.666 -4.435 54.413 1.00 38.34 ? 178 LYS B C 1 ATOM 4492 O O . LYS B 1 178 ? 5.583 -3.306 54.906 1.00 36.53 ? 178 LYS B O 1 ATOM 4493 C CB . LYS B 1 178 ? 3.692 -5.663 53.475 1.00 37.05 ? 178 LYS B CB 1 ATOM 4494 C CG . LYS B 1 178 ? 2.752 -5.095 54.539 1.00 39.31 ? 178 LYS B CG 1 ATOM 4495 C CD . LYS B 1 178 ? 1.977 -3.884 54.045 1.00 41.65 ? 178 LYS B CD 1 ATOM 4496 C CE . LYS B 1 178 ? 1.045 -3.384 55.141 1.00 46.65 ? 178 LYS B CE 1 ATOM 4497 N NZ . LYS B 1 178 ? 0.380 -4.548 55.813 1.00 38.51 ? 178 LYS B NZ 1 ATOM 4498 N N . SER B 1 179 ? 6.431 -5.390 54.945 1.00 34.67 ? 179 SER B N 1 ATOM 4499 C CA . SER B 1 179 ? 7.208 -5.169 56.160 1.00 38.45 ? 179 SER B CA 1 ATOM 4500 C C . SER B 1 179 ? 8.410 -4.256 55.950 1.00 39.57 ? 179 SER B C 1 ATOM 4501 O O . SER B 1 179 ? 9.051 -3.873 56.935 1.00 44.20 ? 179 SER B O 1 ATOM 4502 C CB . SER B 1 179 ? 7.681 -6.508 56.722 1.00 38.12 ? 179 SER B CB 1 ATOM 4503 O OG . SER B 1 179 ? 8.629 -7.105 55.856 1.00 37.61 ? 179 SER B OG 1 ATOM 4504 N N . GLY B 1 180 ? 8.740 -3.901 54.712 1.00 34.95 ? 180 GLY B N 1 ATOM 4505 C CA . GLY B 1 180 ? 9.935 -3.132 54.454 1.00 33.97 ? 180 GLY B CA 1 ATOM 4506 C C . GLY B 1 180 ? 11.229 -3.926 54.453 1.00 34.83 ? 180 GLY B C 1 ATOM 4507 O O . GLY B 1 180 ? 12.297 -3.329 54.256 1.00 35.44 ? 180 GLY B O 1 ATOM 4508 N N . ARG B 1 181 ? 11.174 -5.247 54.659 1.00 33.81 ? 181 ARG B N 1 ATOM 4509 C CA . ARG B 1 181 ? 12.380 -6.066 54.532 1.00 31.00 ? 181 ARG B CA 1 ATOM 4510 C C . ARG B 1 181 ? 12.941 -6.038 53.114 1.00 30.47 ? 181 ARG B C 1 ATOM 4511 O O . ARG B 1 181 ? 14.149 -6.240 52.923 1.00 29.66 ? 181 ARG B O 1 ATOM 4512 C CB . ARG B 1 181 ? 12.093 -7.503 54.954 1.00 33.35 ? 181 ARG B CB 1 ATOM 4513 C CG . ARG B 1 181 ? 12.018 -7.710 56.461 1.00 40.50 ? 181 ARG B CG 1 ATOM 4514 C CD . ARG B 1 181 ? 11.739 -9.168 56.831 1.00 41.47 ? 181 ARG B CD 1 ATOM 4515 N NE . ARG B 1 181 ? 10.374 -9.564 56.492 1.00 45.25 ? 181 ARG B NE 1 ATOM 4516 C CZ . ARG B 1 181 ? 10.049 -10.549 55.657 1.00 41.39 ? 181 ARG B CZ 1 ATOM 4517 N NH1 . ARG B 1 181 ? 10.992 -11.268 55.062 1.00 47.43 ? 181 ARG B NH1 1 ATOM 4518 N NH2 . ARG B 1 181 ? 8.771 -10.821 55.424 1.00 45.26 ? 181 ARG B NH2 1 ATOM 4519 N N . ALA B 1 182 ? 12.091 -5.791 52.113 1.00 26.88 ? 182 ALA B N 1 ATOM 4520 C CA . ALA B 1 182 ? 12.511 -5.629 50.724 1.00 26.20 ? 182 ALA B CA 1 ATOM 4521 C C . ALA B 1 182 ? 11.942 -4.339 50.148 1.00 28.31 ? 182 ALA B C 1 ATOM 4522 O O . ALA B 1 182 ? 10.826 -3.941 50.490 1.00 29.51 ? 182 ALA B O 1 ATOM 4523 C CB . ALA B 1 182 ? 12.048 -6.817 49.860 1.00 23.48 ? 182 ALA B CB 1 ATOM 4524 N N . ASP B 1 183 ? 12.717 -3.695 49.271 1.00 26.46 ? 183 ASP B N 1 ATOM 4525 C CA . ASP B 1 183 ? 12.255 -2.609 48.410 1.00 28.21 ? 183 ASP B CA 1 ATOM 4526 C C . ASP B 1 183 ? 12.004 -3.058 46.978 1.00 26.07 ? 183 ASP B C 1 ATOM 4527 O O . ASP B 1 183 ? 11.168 -2.462 46.286 1.00 25.75 ? 183 ASP B O 1 ATOM 4528 C CB . ASP B 1 183 ? 13.285 -1.477 48.367 1.00 28.01 ? 183 ASP B CB 1 ATOM 4529 C CG . ASP B 1 183 ? 13.617 -0.935 49.744 1.00 36.99 ? 183 ASP B CG 1 ATOM 4530 O OD1 . ASP B 1 183 ? 12.682 -0.570 50.491 1.00 36.41 ? 183 ASP B OD1 1 ATOM 4531 O OD2 . ASP B 1 183 ? 14.819 -0.888 50.084 1.00 34.41 ? 183 ASP B OD2 1 ATOM 4532 N N . LEU B 1 184 ? 12.763 -4.048 46.505 1.00 24.86 ? 184 LEU B N 1 ATOM 4533 C CA . LEU B 1 184 ? 12.520 -4.734 45.240 1.00 19.83 ? 184 LEU B CA 1 ATOM 4534 C C . LEU B 1 184 ? 12.386 -6.210 45.548 1.00 23.02 ? 184 LEU B C 1 ATOM 4535 O O . LEU B 1 184 ? 13.210 -6.766 46.283 1.00 20.41 ? 184 LEU B O 1 ATOM 4536 C CB . LEU B 1 184 ? 13.662 -4.535 44.226 1.00 20.07 ? 184 LEU B CB 1 ATOM 4537 C CG . LEU B 1 184 ? 13.652 -5.507 43.037 1.00 20.78 ? 184 LEU B CG 1 ATOM 4538 C CD1 . LEU B 1 184 ? 12.454 -5.156 42.125 1.00 22.24 ? 184 LEU B CD1 1 ATOM 4539 C CD2 . LEU B 1 184 ? 14.965 -5.465 42.262 1.00 22.93 ? 184 LEU B CD2 1 ATOM 4540 N N . ALA B 1 185 ? 11.354 -6.843 44.997 1.00 21.62 ? 185 ALA B N 1 ATOM 4541 C CA . ALA B 1 185 ? 11.231 -8.293 45.045 1.00 18.38 ? 185 ALA B CA 1 ATOM 4542 C C . ALA B 1 185 ? 11.066 -8.786 43.619 1.00 20.10 ? 185 ALA B C 1 ATOM 4543 O O . ALA B 1 185 ? 10.297 -8.215 42.841 1.00 18.18 ? 185 ALA B O 1 ATOM 4544 C CB . ALA B 1 185 ? 10.054 -8.745 45.916 1.00 19.01 ? 185 ALA B CB 1 ATOM 4545 N N . ALA B 1 186 ? 11.805 -9.824 43.273 1.00 16.99 ? 186 ALA B N 1 ATOM 4546 C CA . ALA B 1 186 ? 11.856 -10.317 41.906 1.00 15.69 ? 186 ALA B CA 1 ATOM 4547 C C . ALA B 1 186 ? 11.631 -11.819 41.926 1.00 15.23 ? 186 ALA B C 1 ATOM 4548 O O . ALA B 1 186 ? 12.334 -12.542 42.640 1.00 19.67 ? 186 ALA B O 1 ATOM 4549 C CB . ALA B 1 186 ? 13.197 -9.972 41.255 1.00 18.15 ? 186 ALA B CB 1 ATOM 4550 N N . ILE B 1 187 ? 10.666 -12.287 41.139 1.00 17.46 ? 187 ILE B N 1 ATOM 4551 C CA . ILE B 1 187 ? 10.243 -13.682 41.162 1.00 16.74 ? 187 ILE B CA 1 ATOM 4552 C C . ILE B 1 187 ? 10.328 -14.253 39.755 1.00 16.86 ? 187 ILE B C 1 ATOM 4553 O O . ILE B 1 187 ? 9.881 -13.619 38.797 1.00 19.18 ? 187 ILE B O 1 ATOM 4554 C CB . ILE B 1 187 ? 8.809 -13.836 41.698 1.00 16.92 ? 187 ILE B CB 1 ATOM 4555 C CG1 . ILE B 1 187 ? 8.660 -13.209 43.076 1.00 19.36 ? 187 ILE B CG1 1 ATOM 4556 C CG2 . ILE B 1 187 ? 8.397 -15.333 41.718 1.00 18.53 ? 187 ILE B CG2 1 ATOM 4557 C CD1 . ILE B 1 187 ? 7.218 -13.268 43.555 1.00 20.65 ? 187 ILE B CD1 1 ATOM 4558 N N . TYR B 1 188 ? 10.880 -15.462 39.641 1.00 16.65 ? 188 TYR B N 1 ATOM 4559 C CA . TYR B 1 188 ? 11.032 -16.177 38.380 1.00 18.16 ? 188 TYR B CA 1 ATOM 4560 C C . TYR B 1 188 ? 10.138 -17.413 38.352 1.00 22.42 ? 188 TYR B C 1 ATOM 4561 O O . TYR B 1 188 ? 10.063 -18.150 39.339 1.00 20.49 ? 188 TYR B O 1 ATOM 4562 C CB . TYR B 1 188 ? 12.501 -16.589 38.187 1.00 17.89 ? 188 TYR B CB 1 ATOM 4563 C CG . TYR B 1 188 ? 12.708 -17.550 37.046 1.00 20.81 ? 188 TYR B CG 1 ATOM 4564 C CD1 . TYR B 1 188 ? 12.756 -17.101 35.740 1.00 17.77 ? 188 TYR B CD1 1 ATOM 4565 C CD2 . TYR B 1 188 ? 12.888 -18.915 37.282 1.00 20.85 ? 188 TYR B CD2 1 ATOM 4566 C CE1 . TYR B 1 188 ? 12.945 -17.974 34.681 1.00 22.71 ? 188 TYR B CE1 1 ATOM 4567 C CE2 . TYR B 1 188 ? 13.080 -19.801 36.225 1.00 25.80 ? 188 TYR B CE2 1 ATOM 4568 C CZ . TYR B 1 188 ? 13.106 -19.324 34.929 1.00 24.53 ? 188 TYR B CZ 1 ATOM 4569 O OH . TYR B 1 188 ? 13.291 -20.190 33.868 1.00 25.74 ? 188 TYR B OH 1 ATOM 4570 N N . HIS B 1 189 ? 9.475 -17.652 37.210 1.00 19.28 ? 189 HIS B N 1 ATOM 4571 C CA . HIS B 1 189 ? 8.607 -18.815 37.022 1.00 21.51 ? 189 HIS B CA 1 ATOM 4572 C C . HIS B 1 189 ? 8.869 -19.445 35.659 1.00 23.28 ? 189 HIS B C 1 ATOM 4573 O O . HIS B 1 189 ? 8.914 -18.737 34.646 1.00 21.38 ? 189 HIS B O 1 ATOM 4574 C CB . HIS B 1 189 ? 7.126 -18.416 37.143 1.00 20.99 ? 189 HIS B CB 1 ATOM 4575 C CG . HIS B 1 189 ? 6.171 -19.567 37.026 1.00 23.69 ? 189 HIS B CG 1 ATOM 4576 N ND1 . HIS B 1 189 ? 6.018 -20.518 38.015 1.00 25.72 ? 189 HIS B ND1 1 ATOM 4577 C CD2 . HIS B 1 189 ? 5.320 -19.920 36.034 1.00 25.10 ? 189 HIS B CD2 1 ATOM 4578 C CE1 . HIS B 1 189 ? 5.104 -21.397 37.643 1.00 26.61 ? 189 HIS B CE1 1 ATOM 4579 N NE2 . HIS B 1 189 ? 4.668 -21.060 36.443 1.00 27.35 ? 189 HIS B NE2 1 ATOM 4580 N N . GLU B 1 190 ? 9.019 -20.781 35.627 1.00 21.75 ? 190 GLU B N 1 ATOM 4581 C CA . GLU B 1 190 ? 9.506 -21.476 34.437 1.00 22.92 ? 190 GLU B CA 1 ATOM 4582 C C . GLU B 1 190 ? 8.472 -22.348 33.721 1.00 24.11 ? 190 GLU B C 1 ATOM 4583 O O . GLU B 1 190 ? 8.668 -22.654 32.538 1.00 22.36 ? 190 GLU B O 1 ATOM 4584 C CB . GLU B 1 190 ? 10.716 -22.362 34.806 1.00 24.61 ? 190 GLU B CB 1 ATOM 4585 C CG . GLU B 1 190 ? 11.523 -22.899 33.612 1.00 28.72 ? 190 GLU B CG 1 ATOM 4586 C CD . GLU B 1 190 ? 12.649 -23.829 34.023 1.00 32.17 ? 190 GLU B CD 1 ATOM 4587 O OE1 . GLU B 1 190 ? 12.827 -24.038 35.239 1.00 26.03 ? 190 GLU B OE1 1 ATOM 4588 O OE2 . GLU B 1 190 ? 13.354 -24.346 33.129 1.00 30.22 ? 190 GLU B OE2 1 ATOM 4589 N N . ARG B 1 191 ? 7.378 -22.742 34.378 1.00 25.06 ? 191 ARG B N 1 ATOM 4590 C CA . ARG B 1 191 ? 6.623 -23.898 33.887 1.00 23.95 ? 191 ARG B CA 1 ATOM 4591 C C . ARG B 1 191 ? 5.906 -23.633 32.560 1.00 29.07 ? 191 ARG B C 1 ATOM 4592 O O . ARG B 1 191 ? 5.591 -24.590 31.841 1.00 26.12 ? 191 ARG B O 1 ATOM 4593 C CB . ARG B 1 191 ? 5.630 -24.385 34.946 1.00 28.54 ? 191 ARG B CB 1 ATOM 4594 C CG . ARG B 1 191 ? 5.529 -25.921 34.987 1.00 40.29 ? 191 ARG B CG 1 ATOM 4595 C CD . ARG B 1 191 ? 4.705 -26.466 36.159 1.00 33.18 ? 191 ARG B CD 1 ATOM 4596 N NE . ARG B 1 191 ? 3.295 -26.090 36.118 1.00 35.09 ? 191 ARG B NE 1 ATOM 4597 C CZ . ARG B 1 191 ? 2.388 -26.627 35.304 1.00 31.65 ? 191 ARG B CZ 1 ATOM 4598 N NH1 . ARG B 1 191 ? 2.735 -27.563 34.431 1.00 43.17 ? 191 ARG B NH1 1 ATOM 4599 N NH2 . ARG B 1 191 ? 1.127 -26.221 35.361 1.00 32.22 ? 191 ARG B NH2 1 ATOM 4600 N N . ILE B 1 192 ? 5.644 -22.371 32.197 1.00 23.97 ? 192 ILE B N 1 ATOM 4601 C CA . ILE B 1 192 ? 5.073 -22.126 30.871 1.00 23.28 ? 192 ILE B CA 1 ATOM 4602 C C . ILE B 1 192 ? 6.092 -22.459 29.785 1.00 23.70 ? 192 ILE B C 1 ATOM 4603 O O . ILE B 1 192 ? 5.739 -22.988 28.720 1.00 25.36 ? 192 ILE B O 1 ATOM 4604 C CB . ILE B 1 192 ? 4.557 -20.674 30.755 1.00 21.24 ? 192 ILE B CB 1 ATOM 4605 C CG1 . ILE B 1 192 ? 3.346 -20.471 31.663 1.00 22.90 ? 192 ILE B CG1 1 ATOM 4606 C CG2 . ILE B 1 192 ? 4.165 -20.345 29.305 1.00 25.22 ? 192 ILE B CG2 1 ATOM 4607 C CD1 . ILE B 1 192 ? 2.930 -19.012 31.811 1.00 27.53 ? 192 ILE B CD1 1 ATOM 4608 N N . ASP B 1 193 ? 7.368 -22.195 30.051 1.00 22.72 ? 193 ASP B N 1 ATOM 4609 C CA . ASP B 1 193 ? 8.428 -22.562 29.125 1.00 22.73 ? 193 ASP B CA 1 ATOM 4610 C C . ASP B 1 193 ? 8.556 -24.078 29.013 1.00 28.10 ? 193 ASP B C 1 ATOM 4611 O O . ASP B 1 193 ? 8.695 -24.620 27.904 1.00 24.47 ? 193 ASP B O 1 ATOM 4612 C CB . ASP B 1 193 ? 9.751 -21.938 29.591 1.00 22.45 ? 193 ASP B CB 1 ATOM 4613 C CG . ASP B 1 193 ? 10.885 -22.135 28.602 1.00 27.86 ? 193 ASP B CG 1 ATOM 4614 O OD1 . ASP B 1 193 ? 10.808 -21.574 27.493 1.00 26.27 ? 193 ASP B OD1 1 ATOM 4615 O OD2 . ASP B 1 193 ? 11.861 -22.844 28.934 1.00 27.39 ? 193 ASP B OD2 1 ATOM 4616 N N . VAL B 1 194 ? 8.515 -24.771 30.152 1.00 24.81 ? 194 VAL B N 1 ATOM 4617 C CA . VAL B 1 194 ? 8.688 -26.225 30.165 1.00 29.37 ? 194 VAL B CA 1 ATOM 4618 C C . VAL B 1 194 ? 7.602 -26.909 29.340 1.00 28.00 ? 194 VAL B C 1 ATOM 4619 O O . VAL B 1 194 ? 7.891 -27.774 28.504 1.00 27.71 ? 194 VAL B O 1 ATOM 4620 C CB . VAL B 1 194 ? 8.700 -26.754 31.610 1.00 30.13 ? 194 VAL B CB 1 ATOM 4621 C CG1 . VAL B 1 194 ? 8.627 -28.304 31.610 1.00 30.68 ? 194 VAL B CG1 1 ATOM 4622 C CG2 . VAL B 1 194 ? 9.939 -26.259 32.364 1.00 25.10 ? 194 VAL B CG2 1 ATOM 4623 N N . GLU B 1 195 ? 6.336 -26.550 29.579 1.00 26.62 ? 195 GLU B N 1 ATOM 4624 C CA . GLU B 1 195 ? 5.241 -27.203 28.868 1.00 27.23 ? 195 GLU B CA 1 ATOM 4625 C C . GLU B 1 195 ? 5.212 -26.809 27.396 1.00 38.94 ? 195 GLU B C 1 ATOM 4626 O O . GLU B 1 195 ? 4.850 -27.629 26.538 1.00 29.79 ? 195 GLU B O 1 ATOM 4627 C CB . GLU B 1 195 ? 3.904 -26.867 29.530 1.00 27.35 ? 195 GLU B CB 1 ATOM 4628 C CG . GLU B 1 195 ? 3.809 -27.263 30.997 1.00 31.21 ? 195 GLU B CG 1 ATOM 4629 C CD . GLU B 1 195 ? 4.018 -28.763 31.223 1.00 41.62 ? 195 GLU B CD 1 ATOM 4630 O OE1 . GLU B 1 195 ? 3.032 -29.524 31.150 1.00 47.31 ? 195 GLU B OE1 1 ATOM 4631 O OE2 . GLU B 1 195 ? 5.168 -29.181 31.469 1.00 43.37 ? 195 GLU B OE2 1 ATOM 4632 N N . GLY B 1 196 ? 5.561 -25.556 27.090 1.00 28.51 ? 196 GLY B N 1 ATOM 4633 C CA . GLY B 1 196 ? 5.777 -25.177 25.705 1.00 29.05 ? 196 GLY B CA 1 ATOM 4634 C C . GLY B 1 196 ? 6.809 -26.051 25.017 1.00 33.24 ? 196 GLY B C 1 ATOM 4635 O O . GLY B 1 196 ? 6.629 -26.447 23.862 1.00 31.41 ? 196 GLY B O 1 ATOM 4636 N N . HIS B 1 197 ? 7.893 -26.379 25.724 1.00 29.27 ? 197 HIS B N 1 ATOM 4637 C CA . HIS B 1 197 ? 8.919 -27.257 25.170 1.00 29.09 ? 197 HIS B CA 1 ATOM 4638 C C . HIS B 1 197 ? 8.386 -28.673 24.986 1.00 32.31 ? 197 HIS B C 1 ATOM 4639 O O . HIS B 1 197 ? 8.462 -29.252 23.894 1.00 32.95 ? 197 HIS B O 1 ATOM 4640 C CB . HIS B 1 197 ? 10.145 -27.287 26.092 1.00 28.52 ? 197 HIS B CB 1 ATOM 4641 C CG . HIS B 1 197 ? 11.101 -26.156 25.883 1.00 28.10 ? 197 HIS B CG 1 ATOM 4642 N ND1 . HIS B 1 197 ? 11.695 -25.898 24.668 1.00 26.54 ? 197 HIS B ND1 1 ATOM 4643 C CD2 . HIS B 1 197 ? 11.582 -25.226 26.742 1.00 25.52 ? 197 HIS B CD2 1 ATOM 4644 C CE1 . HIS B 1 197 ? 12.493 -24.852 24.784 1.00 28.72 ? 197 HIS B CE1 1 ATOM 4645 N NE2 . HIS B 1 197 ? 12.447 -24.429 26.034 1.00 23.12 ? 197 HIS B NE2 1 ATOM 4646 N N . HIS B 1 198 ? 7.852 -29.251 26.060 1.00 33.29 ? 198 HIS B N 1 ATOM 4647 C CA . HIS B 1 198 ? 7.568 -30.680 26.063 1.00 30.88 ? 198 HIS B CA 1 ATOM 4648 C C . HIS B 1 198 ? 6.358 -31.029 25.208 1.00 36.21 ? 198 HIS B C 1 ATOM 4649 O O . HIS B 1 198 ? 6.269 -32.153 24.701 1.00 36.50 ? 198 HIS B O 1 ATOM 4650 C CB . HIS B 1 198 ? 7.364 -31.159 27.494 1.00 32.19 ? 198 HIS B CB 1 ATOM 4651 C CG . HIS B 1 198 ? 8.611 -31.114 28.320 1.00 33.94 ? 198 HIS B CG 1 ATOM 4652 N ND1 . HIS B 1 198 ? 8.612 -31.339 29.680 1.00 32.62 ? 198 HIS B ND1 1 ATOM 4653 C CD2 . HIS B 1 198 ? 9.896 -30.865 27.976 1.00 29.77 ? 198 HIS B CD2 1 ATOM 4654 C CE1 . HIS B 1 198 ? 9.847 -31.228 30.137 1.00 30.52 ? 198 HIS B CE1 1 ATOM 4655 N NE2 . HIS B 1 198 ? 10.644 -30.938 29.125 1.00 28.10 ? 198 HIS B NE2 1 ATOM 4656 N N . TYR B 1 199 ? 5.425 -30.093 25.025 1.00 33.83 ? 199 TYR B N 1 ATOM 4657 C CA . TYR B 1 199 ? 4.196 -30.385 24.303 1.00 35.47 ? 199 TYR B CA 1 ATOM 4658 C C . TYR B 1 199 ? 3.891 -29.435 23.154 1.00 39.72 ? 199 TYR B C 1 ATOM 4659 O O . TYR B 1 199 ? 2.978 -29.724 22.373 1.00 36.51 ? 199 TYR B O 1 ATOM 4660 C CB . TYR B 1 199 ? 3.001 -30.394 25.271 1.00 39.33 ? 199 TYR B CB 1 ATOM 4661 C CG . TYR B 1 199 ? 3.137 -31.419 26.365 1.00 42.10 ? 199 TYR B CG 1 ATOM 4662 C CD1 . TYR B 1 199 ? 2.745 -32.737 26.163 1.00 43.77 ? 199 TYR B CD1 1 ATOM 4663 C CD2 . TYR B 1 199 ? 3.677 -31.076 27.598 1.00 38.59 ? 199 TYR B CD2 1 ATOM 4664 C CE1 . TYR B 1 199 ? 2.882 -33.684 27.164 1.00 41.00 ? 199 TYR B CE1 1 ATOM 4665 C CE2 . TYR B 1 199 ? 3.814 -32.011 28.605 1.00 39.08 ? 199 TYR B CE2 1 ATOM 4666 C CZ . TYR B 1 199 ? 3.416 -33.315 28.383 1.00 46.66 ? 199 TYR B CZ 1 ATOM 4667 O OH . TYR B 1 199 ? 3.554 -34.248 29.385 1.00 45.44 ? 199 TYR B OH 1 ATOM 4668 N N . GLY B 1 200 ? 4.614 -28.327 23.012 1.00 36.65 ? 200 GLY B N 1 ATOM 4669 C CA . GLY B 1 200 ? 4.329 -27.377 21.963 1.00 31.51 ? 200 GLY B CA 1 ATOM 4670 C C . GLY B 1 200 ? 3.555 -26.174 22.462 1.00 28.95 ? 200 GLY B C 1 ATOM 4671 O O . GLY B 1 200 ? 2.747 -26.266 23.393 1.00 28.95 ? 200 GLY B O 1 ATOM 4672 N N . PRO B 1 201 ? 3.780 -25.018 21.829 1.00 27.02 ? 201 PRO B N 1 ATOM 4673 C CA . PRO B 1 201 ? 3.114 -23.781 22.284 1.00 34.22 ? 201 PRO B CA 1 ATOM 4674 C C . PRO B 1 201 ? 1.597 -23.809 22.207 1.00 34.65 ? 201 PRO B C 1 ATOM 4675 O O . PRO B 1 201 ? 0.941 -23.099 22.979 1.00 33.63 ? 201 PRO B O 1 ATOM 4676 C CB . PRO B 1 201 ? 3.698 -22.706 21.352 1.00 31.52 ? 201 PRO B CB 1 ATOM 4677 C CG . PRO B 1 201 ? 4.246 -23.470 20.158 1.00 32.23 ? 201 PRO B CG 1 ATOM 4678 C CD . PRO B 1 201 ? 4.735 -24.766 20.738 1.00 31.99 ? 201 PRO B CD 1 ATOM 4679 N N A SER B 1 202 ? 1.016 -24.595 21.302 0.50 30.83 ? 202 SER B N 1 ATOM 4680 N N C SER B 1 202 ? 1.015 -24.596 21.304 0.50 30.83 ? 202 SER B N 1 ATOM 4681 C CA A SER B 1 202 ? -0.431 -24.658 21.154 0.50 34.01 ? 202 SER B CA 1 ATOM 4682 C CA C SER B 1 202 ? -0.434 -24.657 21.162 0.50 34.01 ? 202 SER B CA 1 ATOM 4683 C C A SER B 1 202 ? -1.065 -25.775 21.976 0.50 35.99 ? 202 SER B C 1 ATOM 4684 C C C SER B 1 202 ? -1.074 -25.745 22.016 0.50 35.99 ? 202 SER B C 1 ATOM 4685 O O A SER B 1 202 ? -2.272 -26.002 21.856 0.50 40.75 ? 202 SER B O 1 ATOM 4686 O O C SER B 1 202 ? -2.295 -25.916 21.960 0.50 40.69 ? 202 SER B O 1 ATOM 4687 C CB A SER B 1 202 ? -0.804 -24.833 19.677 0.50 35.79 ? 202 SER B CB 1 ATOM 4688 C CB C SER B 1 202 ? -0.811 -24.877 19.691 0.50 35.80 ? 202 SER B CB 1 ATOM 4689 O OG A SER B 1 202 ? -0.494 -26.143 19.230 0.50 34.92 ? 202 SER B OG 1 ATOM 4690 O OG C SER B 1 202 ? -0.056 -24.031 18.845 0.50 39.21 ? 202 SER B OG 1 ATOM 4691 N N . SER B 1 203 ? -0.290 -26.461 22.817 1.00 32.49 ? 203 SER B N 1 ATOM 4692 C CA . SER B 1 203 ? -0.784 -27.645 23.502 1.00 34.03 ? 203 SER B CA 1 ATOM 4693 C C . SER B 1 203 ? -1.691 -27.298 24.681 1.00 35.93 ? 203 SER B C 1 ATOM 4694 O O . SER B 1 203 ? -1.568 -26.226 25.287 1.00 40.77 ? 203 SER B O 1 ATOM 4695 C CB . SER B 1 203 ? 0.384 -28.483 24.006 1.00 36.98 ? 203 SER B CB 1 ATOM 4696 O OG . SER B 1 203 ? 1.149 -27.742 24.940 1.00 36.46 ? 203 SER B OG 1 ATOM 4697 N N . PRO B 1 204 ? -2.613 -28.198 25.026 1.00 39.88 ? 204 PRO B N 1 ATOM 4698 C CA . PRO B 1 204 ? -3.403 -27.999 26.251 1.00 35.95 ? 204 PRO B CA 1 ATOM 4699 C C . PRO B 1 204 ? -2.543 -27.956 27.496 1.00 34.21 ? 204 PRO B C 1 ATOM 4700 O O . PRO B 1 204 ? -2.903 -27.279 28.466 1.00 37.20 ? 204 PRO B O 1 ATOM 4701 C CB . PRO B 1 204 ? -4.347 -29.212 26.265 1.00 42.42 ? 204 PRO B CB 1 ATOM 4702 C CG . PRO B 1 204 ? -4.311 -29.760 24.863 1.00 36.34 ? 204 PRO B CG 1 ATOM 4703 C CD . PRO B 1 204 ? -2.955 -29.454 24.336 1.00 35.69 ? 204 PRO B CD 1 ATOM 4704 N N . GLN B 1 205 ? -1.415 -28.666 27.500 1.00 33.09 ? 205 GLN B N 1 ATOM 4705 C CA . GLN B 1 205 ? -0.534 -28.633 28.662 1.00 34.62 ? 205 GLN B CA 1 ATOM 4706 C C . GLN B 1 205 ? 0.066 -27.242 28.865 1.00 34.77 ? 205 GLN B C 1 ATOM 4707 O O . GLN B 1 205 ? 0.136 -26.756 29.997 1.00 33.85 ? 205 GLN B O 1 ATOM 4708 C CB . GLN B 1 205 ? 0.565 -29.678 28.521 1.00 36.42 ? 205 GLN B CB 1 ATOM 4709 C CG . GLN B 1 205 ? 0.069 -31.128 28.590 1.00 39.13 ? 205 GLN B CG 1 ATOM 4710 C CD . GLN B 1 205 ? -0.578 -31.591 27.294 1.00 46.31 ? 205 GLN B CD 1 ATOM 4711 O OE1 . GLN B 1 205 ? -0.543 -30.888 26.284 1.00 39.11 ? 205 GLN B OE1 1 ATOM 4712 N NE2 . GLN B 1 205 ? -1.172 -32.784 27.319 1.00 45.10 ? 205 GLN B NE2 1 ATOM 4713 N N . ARG B 1 206 ? 0.501 -26.585 27.784 1.00 33.49 ? 206 ARG B N 1 ATOM 4714 C CA . ARG B 1 206 ? 0.991 -25.214 27.919 1.00 33.30 ? 206 ARG B CA 1 ATOM 4715 C C . ARG B 1 206 ? -0.118 -24.294 28.406 1.00 32.50 ? 206 ARG B C 1 ATOM 4716 O O . ARG B 1 206 ? 0.111 -23.422 29.256 1.00 29.63 ? 206 ARG B O 1 ATOM 4717 C CB . ARG B 1 206 ? 1.569 -24.719 26.589 1.00 31.82 ? 206 ARG B CB 1 ATOM 4718 C CG . ARG B 1 206 ? 2.337 -23.387 26.654 1.00 28.47 ? 206 ARG B CG 1 ATOM 4719 C CD . ARG B 1 206 ? 1.403 -22.178 26.575 1.00 30.09 ? 206 ARG B CD 1 ATOM 4720 N NE . ARG B 1 206 ? 0.618 -22.150 25.337 1.00 26.80 ? 206 ARG B NE 1 ATOM 4721 C CZ . ARG B 1 206 ? -0.439 -21.365 25.149 1.00 29.68 ? 206 ARG B CZ 1 ATOM 4722 N NH1 . ARG B 1 206 ? -0.843 -20.552 26.117 1.00 27.43 ? 206 ARG B NH1 1 ATOM 4723 N NH2 . ARG B 1 206 ? -1.098 -21.391 23.995 1.00 31.04 ? 206 ARG B NH2 1 ATOM 4724 N N . LYS B 1 207 ? -1.331 -24.472 27.881 1.00 31.20 ? 207 LYS B N 1 ATOM 4725 C CA . LYS B 1 207 ? -2.438 -23.606 28.275 1.00 34.16 ? 207 LYS B CA 1 ATOM 4726 C C . LYS B 1 207 ? -2.791 -23.797 29.743 1.00 32.80 ? 207 LYS B C 1 ATOM 4727 O O . LYS B 1 207 ? -3.140 -22.831 30.437 1.00 30.79 ? 207 LYS B O 1 ATOM 4728 C CB . LYS B 1 207 ? -3.657 -23.872 27.386 1.00 32.92 ? 207 LYS B CB 1 ATOM 4729 C CG . LYS B 1 207 ? -3.513 -23.324 25.978 1.00 30.53 ? 207 LYS B CG 1 ATOM 4730 C CD . LYS B 1 207 ? -4.594 -23.894 25.059 1.00 39.48 ? 207 LYS B CD 1 ATOM 4731 C CE . LYS B 1 207 ? -4.445 -23.349 23.643 1.00 42.36 ? 207 LYS B CE 1 ATOM 4732 N NZ . LYS B 1 207 ? -5.094 -24.244 22.636 1.00 46.10 ? 207 LYS B NZ 1 ATOM 4733 N N . ASP B 1 208 ? -2.708 -25.037 30.231 1.00 30.38 ? 208 ASP B N 1 ATOM 4734 C CA . ASP B 1 208 ? -2.947 -25.307 31.646 1.00 32.24 ? 208 ASP B CA 1 ATOM 4735 C C . ASP B 1 208 ? -1.921 -24.602 32.521 1.00 26.42 ? 208 ASP B C 1 ATOM 4736 O O . ASP B 1 208 ? -2.264 -24.061 33.576 1.00 29.95 ? 208 ASP B O 1 ATOM 4737 C CB . ASP B 1 208 ? -2.908 -26.813 31.925 1.00 32.43 ? 208 ASP B CB 1 ATOM 4738 C CG . ASP B 1 208 ? -4.158 -27.531 31.465 1.00 46.30 ? 208 ASP B CG 1 ATOM 4739 O OD1 . ASP B 1 208 ? -5.174 -26.854 31.190 1.00 42.58 ? 208 ASP B OD1 1 ATOM 4740 O OD2 . ASP B 1 208 ? -4.122 -28.783 31.390 1.00 48.22 ? 208 ASP B OD2 1 ATOM 4741 N N . ALA B 1 209 ? -0.650 -24.629 32.119 1.00 26.98 ? 209 ALA B N 1 ATOM 4742 C CA . ALA B 1 209 ? 0.369 -23.920 32.889 1.00 29.36 ? 209 ALA B CA 1 ATOM 4743 C C . ALA B 1 209 ? 0.078 -22.427 32.909 1.00 30.07 ? 209 ALA B C 1 ATOM 4744 O O . ALA B 1 209 ? 0.238 -21.767 33.941 1.00 26.12 ? 209 ALA B O 1 ATOM 4745 C CB . ALA B 1 209 ? 1.758 -24.196 32.322 1.00 27.30 ? 209 ALA B CB 1 ATOM 4746 N N . LEU B 1 210 ? -0.365 -21.879 31.775 1.00 24.61 ? 210 LEU B N 1 ATOM 4747 C CA . LEU B 1 210 ? -0.724 -20.465 31.730 1.00 24.43 ? 210 LEU B CA 1 ATOM 4748 C C . LEU B 1 210 ? -1.911 -20.168 32.636 1.00 30.84 ? 210 LEU B C 1 ATOM 4749 O O . LEU B 1 210 ? -1.939 -19.140 33.333 1.00 26.17 ? 210 LEU B O 1 ATOM 4750 C CB . LEU B 1 210 ? -1.029 -20.055 30.286 1.00 24.26 ? 210 LEU B CB 1 ATOM 4751 C CG . LEU B 1 210 ? -1.685 -18.684 30.114 1.00 28.26 ? 210 LEU B CG 1 ATOM 4752 C CD1 . LEU B 1 210 ? -0.772 -17.636 30.681 1.00 34.18 ? 210 LEU B CD1 1 ATOM 4753 C CD2 . LEU B 1 210 ? -1.981 -18.409 28.655 1.00 29.54 ? 210 LEU B CD2 1 ATOM 4754 N N . ARG B 1 211 ? -2.907 -21.054 32.640 1.00 28.15 ? 211 ARG B N 1 ATOM 4755 C CA . ARG B 1 211 ? -4.064 -20.840 33.498 1.00 26.15 ? 211 ARG B CA 1 ATOM 4756 C C . ARG B 1 211 ? -3.683 -20.883 34.968 1.00 24.77 ? 211 ARG B C 1 ATOM 4757 O O . ARG B 1 211 ? -4.252 -20.139 35.771 1.00 28.11 ? 211 ARG B O 1 ATOM 4758 C CB . ARG B 1 211 ? -5.152 -21.861 33.165 1.00 33.30 ? 211 ARG B CB 1 ATOM 4759 C CG . ARG B 1 211 ? -5.717 -21.564 31.794 1.00 41.28 ? 211 ARG B CG 1 ATOM 4760 C CD . ARG B 1 211 ? -6.839 -22.480 31.353 1.00 50.68 ? 211 ARG B CD 1 ATOM 4761 N NE . ARG B 1 211 ? -7.184 -22.141 29.976 1.00 54.03 ? 211 ARG B NE 1 ATOM 4762 C CZ . ARG B 1 211 ? -7.944 -21.105 29.636 1.00 55.97 ? 211 ARG B CZ 1 ATOM 4763 N NH1 . ARG B 1 211 ? -8.456 -20.319 30.577 1.00 50.52 ? 211 ARG B NH1 1 ATOM 4764 N NH2 . ARG B 1 211 ? -8.197 -20.858 28.356 1.00 57.51 ? 211 ARG B NH2 1 ATOM 4765 N N . ALA B 1 212 ? -2.694 -21.701 35.334 1.00 27.84 ? 212 ALA B N 1 ATOM 4766 C CA . ALA B 1 212 ? -2.245 -21.702 36.723 1.00 27.95 ? 212 ALA B CA 1 ATOM 4767 C C . ALA B 1 212 ? -1.631 -20.355 37.098 1.00 28.22 ? 212 ALA B C 1 ATOM 4768 O O . ALA B 1 212 ? -1.901 -19.821 38.181 1.00 22.47 ? 212 ALA B O 1 ATOM 4769 C CB . ALA B 1 212 ? -1.251 -22.841 36.947 1.00 26.52 ? 212 ALA B CB 1 ATOM 4770 N N . VAL B 1 213 ? -0.828 -19.775 36.198 1.00 23.86 ? 213 VAL B N 1 ATOM 4771 C CA . VAL B 1 213 ? -0.234 -18.459 36.448 1.00 23.65 ? 213 VAL B CA 1 ATOM 4772 C C . VAL B 1 213 ? -1.312 -17.393 36.544 1.00 22.96 ? 213 VAL B C 1 ATOM 4773 O O . VAL B 1 213 ? -1.253 -16.501 37.402 1.00 23.71 ? 213 VAL B O 1 ATOM 4774 C CB . VAL B 1 213 ? 0.793 -18.123 35.348 1.00 25.97 ? 213 VAL B CB 1 ATOM 4775 C CG1 . VAL B 1 213 ? 1.172 -16.633 35.375 1.00 24.95 ? 213 VAL B CG1 1 ATOM 4776 C CG2 . VAL B 1 213 ? 2.021 -18.983 35.507 1.00 25.61 ? 213 VAL B CG2 1 ATOM 4777 N N . ASP B 1 214 ? -2.308 -17.466 35.658 1.00 22.15 ? 214 ASP B N 1 ATOM 4778 C CA . ASP B 1 214 ? -3.415 -16.519 35.654 1.00 24.44 ? 214 ASP B CA 1 ATOM 4779 C C . ASP B 1 214 ? -4.139 -16.509 36.991 1.00 23.72 ? 214 ASP B C 1 ATOM 4780 O O . ASP B 1 214 ? -4.502 -15.447 37.503 1.00 23.65 ? 214 ASP B O 1 ATOM 4781 C CB . ASP B 1 214 ? -4.394 -16.884 34.544 1.00 22.75 ? 214 ASP B CB 1 ATOM 4782 C CG . ASP B 1 214 ? -5.478 -15.857 34.381 1.00 30.92 ? 214 ASP B CG 1 ATOM 4783 O OD1 . ASP B 1 214 ? -6.513 -15.961 35.069 1.00 33.93 ? 214 ASP B OD1 1 ATOM 4784 O OD2 . ASP B 1 214 ? -5.281 -14.923 33.585 1.00 31.23 ? 214 ASP B OD2 1 ATOM 4785 N N . THR B 1 215 ? -4.358 -17.688 37.566 1.00 24.06 ? 215 THR B N 1 ATOM 4786 C CA . THR B 1 215 ? -4.998 -17.776 38.873 1.00 27.90 ? 215 THR B CA 1 ATOM 4787 C C . THR B 1 215 ? -4.126 -17.157 39.962 1.00 24.05 ? 215 THR B C 1 ATOM 4788 O O . THR B 1 215 ? -4.622 -16.425 40.824 1.00 28.23 ? 215 THR B O 1 ATOM 4789 C CB . THR B 1 215 ? -5.304 -19.241 39.173 1.00 29.49 ? 215 THR B CB 1 ATOM 4790 O OG1 . THR B 1 215 ? -6.252 -19.721 38.210 1.00 33.76 ? 215 THR B OG1 1 ATOM 4791 C CG2 . THR B 1 215 ? -5.857 -19.420 40.580 1.00 31.93 ? 215 THR B CG2 1 ATOM 4792 N N . VAL B 1 216 ? -2.822 -17.420 39.925 1.00 24.85 ? 216 VAL B N 1 ATOM 4793 C CA . VAL B 1 216 ? -1.925 -16.841 40.919 1.00 24.00 ? 216 VAL B CA 1 ATOM 4794 C C . VAL B 1 216 ? -1.940 -15.321 40.827 1.00 23.34 ? 216 VAL B C 1 ATOM 4795 O O . VAL B 1 216 ? -1.905 -14.620 41.848 1.00 23.04 ? 216 VAL B O 1 ATOM 4796 C CB . VAL B 1 216 ? -0.501 -17.406 40.748 1.00 23.69 ? 216 VAL B CB 1 ATOM 4797 C CG1 . VAL B 1 216 ? 0.499 -16.590 41.570 1.00 25.83 ? 216 VAL B CG1 1 ATOM 4798 C CG2 . VAL B 1 216 ? -0.450 -18.881 41.148 1.00 27.30 ? 216 VAL B CG2 1 ATOM 4799 N N . LEU B 1 217 ? -2.004 -14.786 39.604 1.00 21.30 ? 217 LEU B N 1 ATOM 4800 C CA . LEU B 1 217 ? -2.039 -13.333 39.437 1.00 25.36 ? 217 LEU B CA 1 ATOM 4801 C C . LEU B 1 217 ? -3.334 -12.738 39.983 1.00 28.08 ? 217 LEU B C 1 ATOM 4802 O O . LEU B 1 217 ? -3.337 -11.620 40.514 1.00 23.19 ? 217 LEU B O 1 ATOM 4803 C CB . LEU B 1 217 ? -1.862 -12.966 37.961 1.00 27.50 ? 217 LEU B CB 1 ATOM 4804 C CG . LEU B 1 217 ? -0.479 -13.250 37.360 1.00 27.45 ? 217 LEU B CG 1 ATOM 4805 C CD1 . LEU B 1 217 ? -0.456 -12.892 35.889 1.00 30.23 ? 217 LEU B CD1 1 ATOM 4806 C CD2 . LEU B 1 217 ? 0.605 -12.464 38.089 1.00 25.72 ? 217 LEU B CD2 1 ATOM 4807 N N . LYS B 1 218 ? -4.445 -13.460 39.843 1.00 25.31 ? 218 LYS B N 1 ATOM 4808 C CA . LYS B 1 218 ? -5.698 -13.031 40.450 1.00 28.10 ? 218 LYS B CA 1 ATOM 4809 C C . LYS B 1 218 ? -5.563 -12.933 41.969 1.00 24.32 ? 218 LYS B C 1 ATOM 4810 O O . LYS B 1 218 ? -6.015 -11.961 42.591 1.00 27.05 ? 218 LYS B O 1 ATOM 4811 C CB . LYS B 1 218 ? -6.804 -14.014 40.047 1.00 35.87 ? 218 LYS B CB 1 ATOM 4812 C CG . LYS B 1 218 ? -8.204 -13.479 40.119 1.00 42.49 ? 218 LYS B CG 1 ATOM 4813 C CD . LYS B 1 218 ? -9.152 -14.324 39.247 1.00 50.60 ? 218 LYS B CD 1 ATOM 4814 C CE . LYS B 1 218 ? -9.406 -15.713 39.831 1.00 52.16 ? 218 LYS B CE 1 ATOM 4815 N NZ . LYS B 1 218 ? -10.519 -16.418 39.119 1.00 51.18 ? 218 LYS B NZ 1 ATOM 4816 N N . TYR B 1 219 ? -4.902 -13.917 42.580 1.00 26.28 ? 219 TYR B N 1 ATOM 4817 C CA . TYR B 1 219 ? -4.661 -13.864 44.019 1.00 24.59 ? 219 TYR B CA 1 ATOM 4818 C C . TYR B 1 219 ? -3.681 -12.753 44.382 1.00 28.33 ? 219 TYR B C 1 ATOM 4819 O O . TYR B 1 219 ? -3.840 -12.082 45.414 1.00 25.51 ? 219 TYR B O 1 ATOM 4820 C CB . TYR B 1 219 ? -4.164 -15.227 44.508 1.00 28.02 ? 219 TYR B CB 1 ATOM 4821 C CG . TYR B 1 219 ? -5.311 -16.179 44.757 1.00 31.73 ? 219 TYR B CG 1 ATOM 4822 C CD1 . TYR B 1 219 ? -5.845 -16.945 43.726 1.00 35.94 ? 219 TYR B CD1 1 ATOM 4823 C CD2 . TYR B 1 219 ? -5.899 -16.271 46.017 1.00 38.65 ? 219 TYR B CD2 1 ATOM 4824 C CE1 . TYR B 1 219 ? -6.918 -17.794 43.947 1.00 35.91 ? 219 TYR B CE1 1 ATOM 4825 C CE2 . TYR B 1 219 ? -6.968 -17.122 46.252 1.00 38.43 ? 219 TYR B CE2 1 ATOM 4826 C CZ . TYR B 1 219 ? -7.473 -17.878 45.214 1.00 36.74 ? 219 TYR B CZ 1 ATOM 4827 O OH . TYR B 1 219 ? -8.535 -18.715 45.447 1.00 43.29 ? 219 TYR B OH 1 ATOM 4828 N N . MET B 1 220 ? -2.653 -12.548 43.551 1.00 26.14 ? 220 MET B N 1 ATOM 4829 C CA . MET B 1 220 ? -1.701 -11.466 43.793 1.00 23.31 ? 220 MET B CA 1 ATOM 4830 C C . MET B 1 220 ? -2.409 -10.120 43.873 1.00 24.63 ? 220 MET B C 1 ATOM 4831 O O . MET B 1 220 ? -2.141 -9.315 44.775 1.00 23.14 ? 220 MET B O 1 ATOM 4832 C CB . MET B 1 220 ? -0.630 -11.461 42.700 1.00 23.23 ? 220 MET B CB 1 ATOM 4833 C CG . MET B 1 220 ? 0.370 -10.303 42.822 1.00 28.21 ? 220 MET B CG 1 ATOM 4834 S SD . MET B 1 220 ? 1.263 -9.978 41.278 1.00 27.39 ? 220 MET B SD 1 ATOM 4835 C CE . MET B 1 220 ? 0.002 -9.121 40.337 1.00 25.72 ? 220 MET B CE 1 ATOM 4836 N N . ILE B 1 221 ? -3.331 -9.862 42.943 1.00 24.06 ? 221 ILE B N 1 ATOM 4837 C CA . ILE B 1 221 ? -4.103 -8.622 42.982 1.00 28.19 ? 221 ILE B CA 1 ATOM 4838 C C . ILE B 1 221 ? -4.885 -8.528 44.290 1.00 28.59 ? 221 ILE B C 1 ATOM 4839 O O . ILE B 1 221 ? -4.894 -7.486 44.964 1.00 26.72 ? 221 ILE B O 1 ATOM 4840 C CB . ILE B 1 221 ? -5.031 -8.535 41.754 1.00 26.42 ? 221 ILE B CB 1 ATOM 4841 C CG1 . ILE B 1 221 ? -4.215 -8.492 40.459 1.00 26.73 ? 221 ILE B CG1 1 ATOM 4842 C CG2 . ILE B 1 221 ? -5.927 -7.311 41.829 1.00 31.69 ? 221 ILE B CG2 1 ATOM 4843 C CD1 . ILE B 1 221 ? -3.412 -7.235 40.299 1.00 34.51 ? 221 ILE B CD1 1 ATOM 4844 N N . GLN B 1 222 ? -5.540 -9.623 44.673 1.00 26.18 ? 222 GLN B N 1 ATOM 4845 C CA . GLN B 1 222 ? -6.333 -9.642 45.900 1.00 29.33 ? 222 GLN B CA 1 ATOM 4846 C C . GLN B 1 222 ? -5.458 -9.401 47.127 1.00 25.90 ? 222 GLN B C 1 ATOM 4847 O O . GLN B 1 222 ? -5.832 -8.644 48.030 1.00 26.58 ? 222 GLN B O 1 ATOM 4848 C CB . GLN B 1 222 ? -7.068 -10.982 46.013 1.00 28.13 ? 222 GLN B CB 1 ATOM 4849 C CG . GLN B 1 222 ? -7.894 -11.146 47.272 1.00 30.91 ? 222 GLN B CG 1 ATOM 4850 C CD . GLN B 1 222 ? -9.209 -10.398 47.199 1.00 34.70 ? 222 GLN B CD 1 ATOM 4851 O OE1 . GLN B 1 222 ? -9.778 -10.236 46.119 1.00 30.60 ? 222 GLN B OE1 1 ATOM 4852 N NE2 . GLN B 1 222 ? -9.690 -9.923 48.348 1.00 29.74 ? 222 GLN B NE2 1 ATOM 4853 N N . TRP B 1 223 ? -4.282 -10.038 47.167 1.00 25.30 ? 223 TRP B N 1 ATOM 4854 C CA . TRP B 1 223 ? -3.392 -9.914 48.318 1.00 27.41 ? 223 TRP B CA 1 ATOM 4855 C C . TRP B 1 223 ? -2.835 -8.502 48.437 1.00 31.75 ? 223 TRP B C 1 ATOM 4856 O O . TRP B 1 223 ? -2.734 -7.960 49.543 1.00 29.51 ? 223 TRP B O 1 ATOM 4857 C CB . TRP B 1 223 ? -2.250 -10.926 48.211 1.00 25.17 ? 223 TRP B CB 1 ATOM 4858 C CG . TRP B 1 223 ? -2.683 -12.343 48.304 1.00 29.44 ? 223 TRP B CG 1 ATOM 4859 C CD1 . TRP B 1 223 ? -3.804 -12.823 48.918 1.00 30.19 ? 223 TRP B CD1 1 ATOM 4860 C CD2 . TRP B 1 223 ? -2.004 -13.477 47.763 1.00 29.69 ? 223 TRP B CD2 1 ATOM 4861 N NE1 . TRP B 1 223 ? -3.861 -14.189 48.794 1.00 30.00 ? 223 TRP B NE1 1 ATOM 4862 C CE2 . TRP B 1 223 ? -2.766 -14.614 48.089 1.00 29.31 ? 223 TRP B CE2 1 ATOM 4863 C CE3 . TRP B 1 223 ? -0.817 -13.642 47.040 1.00 26.56 ? 223 TRP B CE3 1 ATOM 4864 C CZ2 . TRP B 1 223 ? -2.383 -15.899 47.718 1.00 31.81 ? 223 TRP B CZ2 1 ATOM 4865 C CZ3 . TRP B 1 223 ? -0.443 -14.916 46.663 1.00 30.57 ? 223 TRP B CZ3 1 ATOM 4866 C CH2 . TRP B 1 223 ? -1.223 -16.029 47.000 1.00 30.71 ? 223 TRP B CH2 1 ATOM 4867 N N . ILE B 1 224 ? -2.443 -7.901 47.309 1.00 29.56 ? 224 ILE B N 1 ATOM 4868 C CA . ILE B 1 224 ? -1.947 -6.528 47.329 1.00 26.41 ? 224 ILE B CA 1 ATOM 4869 C C . ILE B 1 224 ? -2.977 -5.614 47.977 1.00 29.70 ? 224 ILE B C 1 ATOM 4870 O O . ILE B 1 224 ? -2.652 -4.781 48.827 1.00 30.51 ? 224 ILE B O 1 ATOM 4871 C CB . ILE B 1 224 ? -1.601 -6.061 45.906 1.00 27.34 ? 224 ILE B CB 1 ATOM 4872 C CG1 . ILE B 1 224 ? -0.343 -6.788 45.410 1.00 25.48 ? 224 ILE B CG1 1 ATOM 4873 C CG2 . ILE B 1 224 ? -1.412 -4.542 45.871 1.00 27.92 ? 224 ILE B CG2 1 ATOM 4874 C CD1 . ILE B 1 224 ? -0.076 -6.578 43.943 1.00 22.13 ? 224 ILE B CD1 1 ATOM 4875 N N . GLN B 1 225 ? -4.239 -5.775 47.599 1.00 27.49 ? 225 GLN B N 1 ATOM 4876 C CA . GLN B 1 225 ? -5.278 -4.930 48.176 1.00 30.81 ? 225 GLN B CA 1 ATOM 4877 C C . GLN B 1 225 ? -5.542 -5.297 49.633 1.00 31.32 ? 225 GLN B C 1 ATOM 4878 O O . GLN B 1 225 ? -5.609 -4.421 50.503 1.00 31.57 ? 225 GLN B O 1 ATOM 4879 C CB . GLN B 1 225 ? -6.544 -5.038 47.331 1.00 38.37 ? 225 GLN B CB 1 ATOM 4880 C CG . GLN B 1 225 ? -6.368 -4.458 45.936 1.00 41.16 ? 225 GLN B CG 1 ATOM 4881 C CD . GLN B 1 225 ? -7.448 -4.896 44.961 1.00 50.59 ? 225 GLN B CD 1 ATOM 4882 O OE1 . GLN B 1 225 ? -8.378 -5.621 45.324 1.00 49.28 ? 225 GLN B OE1 1 ATOM 4883 N NE2 . GLN B 1 225 ? -7.329 -4.455 43.714 1.00 49.07 ? 225 GLN B NE2 1 ATOM 4884 N N . ASP B 1 226 ? -5.666 -6.591 49.926 1.00 30.31 ? 226 ASP B N 1 ATOM 4885 C CA . ASP B 1 226 ? -6.049 -6.999 51.272 1.00 32.31 ? 226 ASP B CA 1 ATOM 4886 C C . ASP B 1 226 ? -4.951 -6.714 52.288 1.00 34.69 ? 226 ASP B C 1 ATOM 4887 O O . ASP B 1 226 ? -5.250 -6.464 53.460 1.00 34.65 ? 226 ASP B O 1 ATOM 4888 C CB . ASP B 1 226 ? -6.427 -8.481 51.285 1.00 28.38 ? 226 ASP B CB 1 ATOM 4889 C CG . ASP B 1 226 ? -7.789 -8.734 50.652 1.00 31.24 ? 226 ASP B CG 1 ATOM 4890 O OD1 . ASP B 1 226 ? -8.516 -7.744 50.398 1.00 35.04 ? 226 ASP B OD1 1 ATOM 4891 O OD2 . ASP B 1 226 ? -8.143 -9.908 50.415 1.00 30.54 ? 226 ASP B OD2 1 ATOM 4892 N N . ARG B 1 227 ? -3.688 -6.738 51.869 1.00 31.65 ? 227 ARG B N 1 ATOM 4893 C CA . ARG B 1 227 ? -2.585 -6.462 52.776 1.00 36.28 ? 227 ARG B CA 1 ATOM 4894 C C . ARG B 1 227 ? -2.207 -4.986 52.794 1.00 36.60 ? 227 ARG B C 1 ATOM 4895 O O . ARG B 1 227 ? -1.222 -4.619 53.435 1.00 41.39 ? 227 ARG B O 1 ATOM 4896 C CB . ARG B 1 227 ? -1.384 -7.347 52.420 1.00 30.17 ? 227 ARG B CB 1 ATOM 4897 C CG . ARG B 1 227 ? -1.788 -8.821 52.361 1.00 38.38 ? 227 ARG B CG 1 ATOM 4898 C CD . ARG B 1 227 ? -0.659 -9.798 52.059 1.00 34.26 ? 227 ARG B CD 1 ATOM 4899 N NE . ARG B 1 227 ? -1.210 -11.130 51.826 1.00 36.40 ? 227 ARG B NE 1 ATOM 4900 C CZ . ARG B 1 227 ? -0.482 -12.210 51.573 1.00 38.01 ? 227 ARG B CZ 1 ATOM 4901 N NH1 . ARG B 1 227 ? 0.836 -12.116 51.527 1.00 35.67 ? 227 ARG B NH1 1 ATOM 4902 N NH2 . ARG B 1 227 ? -1.074 -13.381 51.362 1.00 40.84 ? 227 ARG B NH2 1 ATOM 4903 N N . GLY B 1 228 ? -2.979 -4.132 52.128 1.00 38.41 ? 228 GLY B N 1 ATOM 4904 C CA . GLY B 1 228 ? -2.765 -2.697 52.211 1.00 41.48 ? 228 GLY B CA 1 ATOM 4905 C C . GLY B 1 228 ? -1.562 -2.176 51.456 1.00 43.05 ? 228 GLY B C 1 ATOM 4906 O O . GLY B 1 228 ? -0.982 -1.160 51.857 1.00 38.63 ? 228 GLY B O 1 ATOM 4907 N N . LEU B 1 229 ? -1.171 -2.837 50.365 1.00 34.13 ? 229 LEU B N 1 ATOM 4908 C CA . LEU B 1 229 ? -0.003 -2.443 49.586 1.00 31.67 ? 229 LEU B CA 1 ATOM 4909 C C . LEU B 1 229 ? -0.338 -1.636 48.336 1.00 29.53 ? 229 LEU B C 1 ATOM 4910 O O . LEU B 1 229 ? 0.582 -1.253 47.609 1.00 32.79 ? 229 LEU B O 1 ATOM 4911 C CB . LEU B 1 229 ? 0.792 -3.690 49.174 1.00 26.96 ? 229 LEU B CB 1 ATOM 4912 C CG . LEU B 1 229 ? 1.774 -4.241 50.189 1.00 40.63 ? 229 LEU B CG 1 ATOM 4913 C CD1 . LEU B 1 229 ? 2.316 -5.584 49.703 1.00 35.56 ? 229 LEU B CD1 1 ATOM 4914 C CD2 . LEU B 1 229 ? 2.898 -3.228 50.385 1.00 38.77 ? 229 LEU B CD2 1 ATOM 4915 N N . GLN B 1 230 ? -1.618 -1.344 48.086 1.00 27.49 ? 230 GLN B N 1 ATOM 4916 C CA . GLN B 1 230 ? -2.033 -0.815 46.789 1.00 29.41 ? 230 GLN B CA 1 ATOM 4917 C C . GLN B 1 230 ? -1.310 0.478 46.429 1.00 29.69 ? 230 GLN B C 1 ATOM 4918 O O . GLN B 1 230 ? -0.881 0.653 45.286 1.00 28.92 ? 230 GLN B O 1 ATOM 4919 C CB . GLN B 1 230 ? -3.546 -0.594 46.770 1.00 44.53 ? 230 GLN B CB 1 ATOM 4920 C CG . GLN B 1 230 ? -4.087 -0.193 45.410 1.00 45.64 ? 230 GLN B CG 1 ATOM 4921 C CD . GLN B 1 230 ? -5.190 -1.116 44.925 1.00 56.26 ? 230 GLN B CD 1 ATOM 4922 O OE1 . GLN B 1 230 ? -6.195 -1.315 45.610 1.00 62.01 ? 230 GLN B OE1 1 ATOM 4923 N NE2 . GLN B 1 230 ? -5.007 -1.684 43.738 1.00 54.41 ? 230 GLN B NE2 1 ATOM 4924 N N . GLN B 1 231 ? -1.167 1.400 47.379 1.00 31.24 ? 231 GLN B N 1 ATOM 4925 C CA . GLN B 1 231 ? -0.566 2.691 47.069 1.00 31.39 ? 231 GLN B CA 1 ATOM 4926 C C . GLN B 1 231 ? 0.957 2.684 47.100 1.00 33.01 ? 231 GLN B C 1 ATOM 4927 O O . GLN B 1 231 ? 1.576 3.646 46.624 1.00 33.39 ? 231 GLN B O 1 ATOM 4928 C CB . GLN B 1 231 ? -1.080 3.763 48.039 1.00 32.31 ? 231 GLN B CB 1 ATOM 4929 C CG . GLN B 1 231 ? -2.533 4.129 47.814 1.00 32.80 ? 231 GLN B CG 1 ATOM 4930 C CD . GLN B 1 231 ? -2.773 4.688 46.422 1.00 38.43 ? 231 GLN B CD 1 ATOM 4931 O OE1 . GLN B 1 231 ? -2.023 5.551 45.944 1.00 44.42 ? 231 GLN B OE1 1 ATOM 4932 N NE2 . GLN B 1 231 ? -3.815 4.201 45.761 1.00 42.14 ? 231 GLN B NE2 1 ATOM 4933 N N . ASP B 1 232 ? 1.584 1.641 47.640 1.00 30.10 ? 232 ASP B N 1 ATOM 4934 C CA . ASP B 1 232 ? 3.036 1.643 47.792 1.00 32.54 ? 232 ASP B CA 1 ATOM 4935 C C . ASP B 1 232 ? 3.746 0.640 46.878 1.00 33.57 ? 232 ASP B C 1 ATOM 4936 O O . ASP B 1 232 ? 4.922 0.337 47.102 1.00 30.79 ? 232 ASP B O 1 ATOM 4937 C CB . ASP B 1 232 ? 3.413 1.381 49.249 1.00 32.10 ? 232 ASP B CB 1 ATOM 4938 C CG . ASP B 1 232 ? 4.834 1.799 49.556 1.00 33.55 ? 232 ASP B CG 1 ATOM 4939 O OD1 . ASP B 1 232 ? 5.302 2.772 48.925 1.00 33.49 ? 232 ASP B OD1 1 ATOM 4940 O OD2 . ASP B 1 232 ? 5.489 1.141 50.391 1.00 37.04 ? 232 ASP B OD2 1 ATOM 4941 N N . LEU B 1 233 ? 3.083 0.146 45.833 1.00 24.44 ? 233 LEU B N 1 ATOM 4942 C CA . LEU B 1 233 ? 3.670 -0.935 45.045 1.00 27.34 ? 233 LEU B CA 1 ATOM 4943 C C . LEU B 1 233 ? 3.283 -0.815 43.578 1.00 26.28 ? 233 LEU B C 1 ATOM 4944 O O . LEU B 1 233 ? 2.109 -0.610 43.260 1.00 26.78 ? 233 LEU B O 1 ATOM 4945 C CB . LEU B 1 233 ? 3.232 -2.296 45.613 1.00 24.13 ? 233 LEU B CB 1 ATOM 4946 C CG . LEU B 1 233 ? 3.672 -3.588 44.917 1.00 23.59 ? 233 LEU B CG 1 ATOM 4947 C CD1 . LEU B 1 233 ? 5.177 -3.730 45.008 1.00 22.05 ? 233 LEU B CD1 1 ATOM 4948 C CD2 . LEU B 1 233 ? 2.981 -4.793 45.545 1.00 26.18 ? 233 LEU B CD2 1 ATOM 4949 N N . ASN B 1 234 ? 4.269 -0.930 42.688 1.00 20.75 ? 234 ASN B N 1 ATOM 4950 C CA . ASN B 1 234 ? 4.023 -1.226 41.284 1.00 21.06 ? 234 ASN B CA 1 ATOM 4951 C C . ASN B 1 234 ? 4.390 -2.679 41.021 1.00 19.58 ? 234 ASN B C 1 ATOM 4952 O O . ASN B 1 234 ? 5.267 -3.232 41.685 1.00 20.49 ? 234 ASN B O 1 ATOM 4953 C CB . ASN B 1 234 ? 4.845 -0.327 40.349 1.00 21.44 ? 234 ASN B CB 1 ATOM 4954 C CG . ASN B 1 234 ? 4.448 1.133 40.443 1.00 26.25 ? 234 ASN B CG 1 ATOM 4955 O OD1 . ASN B 1 234 ? 3.334 1.501 40.076 1.00 27.60 ? 234 ASN B OD1 1 ATOM 4956 N ND2 . ASN B 1 234 ? 5.363 1.972 40.916 1.00 24.33 ? 234 ASN B ND2 1 ATOM 4957 N N . VAL B 1 235 ? 3.715 -3.301 40.052 1.00 19.17 ? 235 VAL B N 1 ATOM 4958 C CA . VAL B 1 235 ? 4.066 -4.649 39.603 1.00 20.80 ? 235 VAL B CA 1 ATOM 4959 C C . VAL B 1 235 ? 4.395 -4.591 38.115 1.00 19.83 ? 235 VAL B C 1 ATOM 4960 O O . VAL B 1 235 ? 3.647 -4.007 37.323 1.00 20.94 ? 235 VAL B O 1 ATOM 4961 C CB . VAL B 1 235 ? 2.942 -5.668 39.875 1.00 20.28 ? 235 VAL B CB 1 ATOM 4962 C CG1 . VAL B 1 235 ? 3.398 -7.081 39.466 1.00 20.18 ? 235 VAL B CG1 1 ATOM 4963 C CG2 . VAL B 1 235 ? 2.556 -5.672 41.358 1.00 20.90 ? 235 VAL B CG2 1 ATOM 4964 N N . ILE B 1 236 ? 5.528 -5.175 37.742 1.00 16.18 ? 236 ILE B N 1 ATOM 4965 C CA . ILE B 1 236 ? 5.963 -5.265 36.356 1.00 16.91 ? 236 ILE B CA 1 ATOM 4966 C C . ILE B 1 236 ? 6.109 -6.740 36.012 1.00 19.25 ? 236 ILE B C 1 ATOM 4967 O O . ILE B 1 236 ? 6.679 -7.505 36.797 1.00 20.32 ? 236 ILE B O 1 ATOM 4968 C CB . ILE B 1 236 ? 7.286 -4.508 36.149 1.00 20.19 ? 236 ILE B CB 1 ATOM 4969 C CG1 . ILE B 1 236 ? 7.019 -2.991 36.126 1.00 20.16 ? 236 ILE B CG1 1 ATOM 4970 C CG2 . ILE B 1 236 ? 7.975 -4.930 34.863 1.00 19.97 ? 236 ILE B CG2 1 ATOM 4971 C CD1 . ILE B 1 236 ? 8.278 -2.138 36.326 1.00 23.88 ? 236 ILE B CD1 1 ATOM 4972 N N . LEU B 1 237 ? 5.578 -7.149 34.861 1.00 18.04 ? 237 LEU B N 1 ATOM 4973 C CA . LEU B 1 237 ? 5.642 -8.540 34.428 1.00 18.21 ? 237 LEU B CA 1 ATOM 4974 C C . LEU B 1 237 ? 6.195 -8.589 33.014 1.00 18.95 ? 237 LEU B C 1 ATOM 4975 O O . LEU B 1 237 ? 5.778 -7.802 32.158 1.00 23.57 ? 237 LEU B O 1 ATOM 4976 C CB . LEU B 1 237 ? 4.261 -9.211 34.432 1.00 21.38 ? 237 LEU B CB 1 ATOM 4977 C CG . LEU B 1 237 ? 3.379 -9.231 35.674 1.00 25.50 ? 237 LEU B CG 1 ATOM 4978 C CD1 . LEU B 1 237 ? 2.608 -7.929 35.850 1.00 24.98 ? 237 LEU B CD1 1 ATOM 4979 C CD2 . LEU B 1 237 ? 2.422 -10.401 35.539 1.00 26.25 ? 237 LEU B CD2 1 ATOM 4980 N N . PHE B 1 238 ? 7.105 -9.521 32.758 1.00 18.94 ? 238 PHE B N 1 ATOM 4981 C CA . PHE B 1 238 ? 7.640 -9.676 31.413 1.00 16.62 ? 238 PHE B CA 1 ATOM 4982 C C . PHE B 1 238 ? 8.141 -11.097 31.209 1.00 20.55 ? 238 PHE B C 1 ATOM 4983 O O . PHE B 1 238 ? 8.189 -11.910 32.142 1.00 19.28 ? 238 PHE B O 1 ATOM 4984 C CB . PHE B 1 238 ? 8.750 -8.654 31.114 1.00 19.14 ? 238 PHE B CB 1 ATOM 4985 C CG . PHE B 1 238 ? 9.783 -8.513 32.189 1.00 21.45 ? 238 PHE B CG 1 ATOM 4986 C CD1 . PHE B 1 238 ? 10.610 -9.586 32.536 1.00 17.86 ? 238 PHE B CD1 1 ATOM 4987 C CD2 . PHE B 1 238 ? 9.963 -7.300 32.828 1.00 17.70 ? 238 PHE B CD2 1 ATOM 4988 C CE1 . PHE B 1 238 ? 11.591 -9.455 33.513 1.00 21.23 ? 238 PHE B CE1 1 ATOM 4989 C CE2 . PHE B 1 238 ? 10.937 -7.150 33.814 1.00 21.33 ? 238 PHE B CE2 1 ATOM 4990 C CZ . PHE B 1 238 ? 11.757 -8.246 34.162 1.00 21.04 ? 238 PHE B CZ 1 ATOM 4991 N N . SER B 1 239 ? 8.539 -11.387 29.971 1.00 18.78 ? 239 SER B N 1 ATOM 4992 C CA . SER B 1 239 ? 9.122 -12.677 29.642 1.00 18.04 ? 239 SER B CA 1 ATOM 4993 C C . SER B 1 239 ? 10.431 -12.474 28.897 1.00 20.00 ? 239 SER B C 1 ATOM 4994 O O . SER B 1 239 ? 10.739 -11.376 28.407 1.00 20.39 ? 239 SER B O 1 ATOM 4995 C CB . SER B 1 239 ? 8.164 -13.529 28.798 1.00 20.17 ? 239 SER B CB 1 ATOM 4996 O OG . SER B 1 239 ? 7.825 -12.855 27.602 1.00 21.19 ? 239 SER B OG 1 ATOM 4997 N N . ASP B 1 240 ? 11.204 -13.554 28.832 1.00 19.02 ? 240 ASP B N 1 ATOM 4998 C CA . ASP B 1 240 ? 12.505 -13.517 28.191 1.00 20.00 ? 240 ASP B CA 1 ATOM 4999 C C . ASP B 1 240 ? 12.431 -13.773 26.693 1.00 20.42 ? 240 ASP B C 1 ATOM 5000 O O . ASP B 1 240 ? 13.295 -13.275 25.973 1.00 20.34 ? 240 ASP B O 1 ATOM 5001 C CB . ASP B 1 240 ? 13.497 -14.513 28.874 1.00 18.59 ? 240 ASP B CB 1 ATOM 5002 C CG . ASP B 1 240 ? 13.002 -15.961 28.944 1.00 22.50 ? 240 ASP B CG 1 ATOM 5003 O OD1 . ASP B 1 240 ? 11.794 -16.230 28.864 1.00 21.25 ? 240 ASP B OD1 1 ATOM 5004 O OD2 . ASP B 1 240 ? 13.871 -16.876 29.093 1.00 24.45 ? 240 ASP B OD2 1 ATOM 5005 N N . HIS B 1 241 ? 11.382 -14.463 26.212 1.00 22.79 ? 241 HIS B N 1 ATOM 5006 C CA . HIS B 1 241 ? 11.199 -14.819 24.802 1.00 25.45 ? 241 HIS B CA 1 ATOM 5007 C C . HIS B 1 241 ? 9.893 -15.584 24.603 1.00 23.99 ? 241 HIS B C 1 ATOM 5008 O O . HIS B 1 241 ? 9.216 -15.926 25.581 1.00 20.80 ? 241 HIS B O 1 ATOM 5009 C CB . HIS B 1 241 ? 12.354 -15.698 24.321 1.00 20.08 ? 241 HIS B CB 1 ATOM 5010 C CG . HIS B 1 241 ? 12.556 -16.886 25.195 1.00 21.31 ? 241 HIS B CG 1 ATOM 5011 N ND1 . HIS B 1 241 ? 11.715 -17.977 25.176 1.00 22.53 ? 241 HIS B ND1 1 ATOM 5012 C CD2 . HIS B 1 241 ? 13.446 -17.113 26.186 1.00 20.49 ? 241 HIS B CD2 1 ATOM 5013 C CE1 . HIS B 1 241 ? 12.093 -18.834 26.103 1.00 21.88 ? 241 HIS B CE1 1 ATOM 5014 N NE2 . HIS B 1 241 ? 13.148 -18.338 26.720 1.00 24.22 ? 241 HIS B NE2 1 ATOM 5015 N N . GLY B 1 242 ? 9.565 -15.910 23.353 1.00 21.91 ? 242 GLY B N 1 ATOM 5016 C CA . GLY B 1 242 ? 8.401 -16.713 22.972 1.00 21.07 ? 242 GLY B CA 1 ATOM 5017 C C . GLY B 1 242 ? 8.731 -18.185 22.790 1.00 26.10 ? 242 GLY B C 1 ATOM 5018 O O . GLY B 1 242 ? 9.598 -18.747 23.475 1.00 24.47 ? 242 GLY B O 1 ATOM 5019 N N . MET B 1 243 ? 8.023 -18.832 21.865 1.00 23.81 ? 243 MET B N 1 ATOM 5020 C CA . MET B 1 243 ? 8.151 -20.274 21.674 1.00 23.95 ? 243 MET B CA 1 ATOM 5021 C C . MET B 1 243 ? 7.561 -20.620 20.311 1.00 24.14 ? 243 MET B C 1 ATOM 5022 O O . MET B 1 243 ? 6.572 -20.019 19.910 1.00 25.57 ? 243 MET B O 1 ATOM 5023 C CB . MET B 1 243 ? 7.414 -21.040 22.783 1.00 24.11 ? 243 MET B CB 1 ATOM 5024 C CG . MET B 1 243 ? 7.482 -22.561 22.688 1.00 27.04 ? 243 MET B CG 1 ATOM 5025 S SD . MET B 1 243 ? 9.002 -23.221 23.378 1.00 28.14 ? 243 MET B SD 1 ATOM 5026 C CE . MET B 1 243 ? 8.847 -22.704 25.106 1.00 23.92 ? 243 MET B CE 1 ATOM 5027 N N . THR B 1 244 ? 8.170 -21.572 19.605 1.00 27.97 ? 244 THR B N 1 ATOM 5028 C CA . THR B 1 244 ? 7.646 -22.004 18.311 1.00 26.56 ? 244 THR B CA 1 ATOM 5029 C C . THR B 1 244 ? 7.703 -23.524 18.201 1.00 31.17 ? 244 THR B C 1 ATOM 5030 O O . THR B 1 244 ? 8.393 -24.196 18.967 1.00 33.52 ? 244 THR B O 1 ATOM 5031 C CB . THR B 1 244 ? 8.409 -21.367 17.141 1.00 29.05 ? 244 THR B CB 1 ATOM 5032 O OG1 . THR B 1 244 ? 7.643 -21.515 15.929 1.00 28.77 ? 244 THR B OG1 1 ATOM 5033 C CG2 . THR B 1 244 ? 9.754 -22.041 16.946 1.00 28.69 ? 244 THR B CG2 1 ATOM 5034 N N . ASP B 1 245 ? 6.954 -24.068 17.243 1.00 35.18 ? 245 ASP B N 1 ATOM 5035 C CA . ASP B 1 245 ? 6.940 -25.514 17.060 1.00 34.53 ? 245 ASP B CA 1 ATOM 5036 C C . ASP B 1 245 ? 8.244 -25.982 16.436 1.00 32.85 ? 245 ASP B C 1 ATOM 5037 O O . ASP B 1 245 ? 8.822 -25.300 15.584 1.00 37.26 ? 245 ASP B O 1 ATOM 5038 C CB . ASP B 1 245 ? 5.768 -25.940 16.176 1.00 34.65 ? 245 ASP B CB 1 ATOM 5039 C CG . ASP B 1 245 ? 4.436 -25.471 16.709 1.00 40.69 ? 245 ASP B CG 1 ATOM 5040 O OD1 . ASP B 1 245 ? 3.891 -26.140 17.609 1.00 37.32 ? 245 ASP B OD1 1 ATOM 5041 O OD2 . ASP B 1 245 ? 3.928 -24.438 16.216 1.00 48.26 ? 245 ASP B OD2 1 ATOM 5042 N N . ILE B 1 246 ? 8.709 -27.157 16.867 1.00 31.32 ? 246 ILE B N 1 ATOM 5043 C CA . ILE B 1 246 ? 9.827 -27.830 16.222 1.00 31.97 ? 246 ILE B CA 1 ATOM 5044 C C . ILE B 1 246 ? 9.358 -29.200 15.743 1.00 37.06 ? 246 ILE B C 1 ATOM 5045 O O . ILE B 1 246 ? 8.337 -29.729 16.189 1.00 35.70 ? 246 ILE B O 1 ATOM 5046 C CB . ILE B 1 246 ? 11.057 -27.962 17.144 1.00 35.57 ? 246 ILE B CB 1 ATOM 5047 C CG1 . ILE B 1 246 ? 10.645 -28.462 18.526 1.00 30.02 ? 246 ILE B CG1 1 ATOM 5048 C CG2 . ILE B 1 246 ? 11.802 -26.638 17.240 1.00 31.72 ? 246 ILE B CG2 1 ATOM 5049 C CD1 . ILE B 1 246 ? 11.818 -28.909 19.365 1.00 33.46 ? 246 ILE B CD1 1 ATOM 5050 N N . PHE B 1 247 ? 10.132 -29.785 14.826 1.00 39.43 ? 247 PHE B N 1 ATOM 5051 C CA . PHE B 1 247 ? 9.677 -30.962 14.080 1.00 37.56 ? 247 PHE B CA 1 ATOM 5052 C C . PHE B 1 247 ? 10.793 -32.008 14.062 1.00 44.16 ? 247 PHE B C 1 ATOM 5053 O O . PHE B 1 247 ? 11.580 -32.089 13.116 1.00 47.95 ? 247 PHE B O 1 ATOM 5054 C CB . PHE B 1 247 ? 9.235 -30.549 12.680 1.00 43.26 ? 247 PHE B CB 1 ATOM 5055 C CG . PHE B 1 247 ? 8.228 -29.420 12.683 1.00 42.34 ? 247 PHE B CG 1 ATOM 5056 C CD1 . PHE B 1 247 ? 6.881 -29.676 12.892 1.00 39.53 ? 247 PHE B CD1 1 ATOM 5057 C CD2 . PHE B 1 247 ? 8.636 -28.104 12.518 1.00 40.38 ? 247 PHE B CD2 1 ATOM 5058 C CE1 . PHE B 1 247 ? 5.953 -28.643 12.918 1.00 46.66 ? 247 PHE B CE1 1 ATOM 5059 C CE2 . PHE B 1 247 ? 7.711 -27.066 12.537 1.00 40.97 ? 247 PHE B CE2 1 ATOM 5060 C CZ . PHE B 1 247 ? 6.369 -27.338 12.743 1.00 39.83 ? 247 PHE B CZ 1 ATOM 5061 N N . TRP B 1 248 ? 10.863 -32.798 15.127 1.00 42.92 ? 248 TRP B N 1 ATOM 5062 C CA . TRP B 1 248 ? 11.727 -33.971 15.163 1.00 51.39 ? 248 TRP B CA 1 ATOM 5063 C C . TRP B 1 248 ? 10.993 -35.137 14.480 1.00 54.58 ? 248 TRP B C 1 ATOM 5064 O O . TRP B 1 248 ? 9.787 -35.302 14.675 1.00 52.17 ? 248 TRP B O 1 ATOM 5065 C CB . TRP B 1 248 ? 12.093 -34.335 16.609 1.00 50.65 ? 248 TRP B CB 1 ATOM 5066 C CG . TRP B 1 248 ? 12.936 -33.310 17.336 1.00 50.78 ? 248 TRP B CG 1 ATOM 5067 C CD1 . TRP B 1 248 ? 13.351 -32.094 16.864 1.00 43.35 ? 248 TRP B CD1 1 ATOM 5068 C CD2 . TRP B 1 248 ? 13.469 -33.426 18.665 1.00 48.55 ? 248 TRP B CD2 1 ATOM 5069 N NE1 . TRP B 1 248 ? 14.107 -31.449 17.817 1.00 45.53 ? 248 TRP B NE1 1 ATOM 5070 C CE2 . TRP B 1 248 ? 14.197 -32.244 18.929 1.00 47.10 ? 248 TRP B CE2 1 ATOM 5071 C CE3 . TRP B 1 248 ? 13.404 -34.414 19.653 1.00 45.54 ? 248 TRP B CE3 1 ATOM 5072 C CZ2 . TRP B 1 248 ? 14.852 -32.025 20.141 1.00 42.22 ? 248 TRP B CZ2 1 ATOM 5073 C CZ3 . TRP B 1 248 ? 14.056 -34.196 20.855 1.00 48.66 ? 248 TRP B CZ3 1 ATOM 5074 C CH2 . TRP B 1 248 ? 14.772 -33.008 21.087 1.00 45.79 ? 248 TRP B CH2 1 ATOM 5075 N N . MET B 1 249 ? 11.687 -35.932 13.669 1.00 51.47 ? 249 MET B N 1 ATOM 5076 C CA . MET B 1 249 ? 13.096 -35.749 13.345 1.00 52.81 ? 249 MET B CA 1 ATOM 5077 C C . MET B 1 249 ? 13.272 -35.198 11.935 1.00 54.36 ? 249 MET B C 1 ATOM 5078 O O . MET B 1 249 ? 14.394 -35.106 11.438 1.00 59.78 ? 249 MET B O 1 ATOM 5079 C CB . MET B 1 249 ? 13.846 -37.078 13.465 1.00 55.74 ? 249 MET B CB 1 ATOM 5080 C CG . MET B 1 249 ? 13.650 -37.790 14.786 1.00 52.37 ? 249 MET B CG 1 ATOM 5081 S SD . MET B 1 249 ? 14.895 -37.291 15.982 1.00 67.42 ? 249 MET B SD 1 ATOM 5082 C CE . MET B 1 249 ? 14.218 -37.992 17.484 1.00 58.00 ? 249 MET B CE 1 ATOM 5083 N N . ASP B 1 250 ? 12.155 -34.841 11.291 1.00 56.53 ? 250 ASP B N 1 ATOM 5084 C CA . ASP B 1 250 ? 12.206 -34.397 9.900 1.00 54.43 ? 250 ASP B CA 1 ATOM 5085 C C . ASP B 1 250 ? 13.040 -33.135 9.723 1.00 56.58 ? 250 ASP B C 1 ATOM 5086 O O . ASP B 1 250 ? 13.586 -32.904 8.639 1.00 56.83 ? 250 ASP B O 1 ATOM 5087 C CB . ASP B 1 250 ? 10.793 -34.158 9.367 1.00 58.58 ? 250 ASP B CB 1 ATOM 5088 C CG . ASP B 1 250 ? 10.153 -35.416 8.825 1.00 69.20 ? 250 ASP B CG 1 ATOM 5089 O OD1 . ASP B 1 250 ? 10.899 -36.357 8.471 1.00 71.68 ? 250 ASP B OD1 1 ATOM 5090 O OD2 . ASP B 1 250 ? 8.906 -35.463 8.743 1.00 66.88 ? 250 ASP B OD2 1 ATOM 5091 N N . LYS B 1 251 ? 13.144 -32.302 10.755 1.00 55.53 ? 251 LYS B N 1 ATOM 5092 C CA . LYS B 1 251 ? 13.822 -31.016 10.639 1.00 51.74 ? 251 LYS B CA 1 ATOM 5093 C C . LYS B 1 251 ? 14.994 -30.900 11.611 1.00 52.45 ? 251 LYS B C 1 ATOM 5094 O O . LYS B 1 251 ? 15.254 -29.836 12.178 1.00 53.57 ? 251 LYS B O 1 ATOM 5095 C CB . LYS B 1 251 ? 12.835 -29.866 10.831 1.00 49.55 ? 251 LYS B CB 1 ATOM 5096 C CG . LYS B 1 251 ? 11.700 -29.871 9.818 1.00 49.18 ? 251 LYS B CG 1 ATOM 5097 C CD . LYS B 1 251 ? 11.076 -28.495 9.642 1.00 49.76 ? 251 LYS B CD 1 ATOM 5098 C CE . LYS B 1 251 ? 9.846 -28.565 8.738 1.00 51.10 ? 251 LYS B CE 1 ATOM 5099 N NZ . LYS B 1 251 ? 9.207 -27.230 8.516 1.00 47.16 ? 251 LYS B NZ 1 ATOM 5100 N N . VAL B 1 252 ? 15.729 -31.991 11.804 1.00 51.61 ? 252 VAL B N 1 ATOM 5101 C CA . VAL B 1 252 ? 16.961 -31.983 12.583 1.00 49.13 ? 252 VAL B CA 1 ATOM 5102 C C . VAL B 1 252 ? 18.134 -31.892 11.620 1.00 49.19 ? 252 VAL B C 1 ATOM 5103 O O . VAL B 1 252 ? 18.165 -32.593 10.602 1.00 55.74 ? 252 VAL B O 1 ATOM 5104 C CB . VAL B 1 252 ? 17.082 -33.235 13.468 1.00 48.59 ? 252 VAL B CB 1 ATOM 5105 C CG1 . VAL B 1 252 ? 18.373 -33.188 14.257 1.00 49.94 ? 252 VAL B CG1 1 ATOM 5106 C CG2 . VAL B 1 252 ? 15.890 -33.357 14.405 1.00 55.33 ? 252 VAL B CG2 1 ATOM 5107 N N . ILE B 1 253 ? 19.087 -31.019 11.927 1.00 51.42 ? 253 ILE B N 1 ATOM 5108 C CA . ILE B 1 253 ? 20.363 -30.950 11.223 1.00 48.72 ? 253 ILE B CA 1 ATOM 5109 C C . ILE B 1 253 ? 21.401 -31.667 12.077 1.00 53.96 ? 253 ILE B C 1 ATOM 5110 O O . ILE B 1 253 ? 21.576 -31.333 13.255 1.00 53.29 ? 253 ILE B O 1 ATOM 5111 C CB . ILE B 1 253 ? 20.786 -29.497 10.960 1.00 37.87 ? 253 ILE B CB 1 ATOM 5112 C CG1 . ILE B 1 253 ? 19.883 -28.850 9.917 1.00 49.91 ? 253 ILE B CG1 1 ATOM 5113 C CG2 . ILE B 1 253 ? 22.248 -29.443 10.545 1.00 44.45 ? 253 ILE B CG2 1 ATOM 5114 C CD1 . ILE B 1 253 ? 20.253 -27.413 9.620 1.00 44.02 ? 253 ILE B CD1 1 ATOM 5115 N N . GLU B 1 254 ? 22.091 -32.650 11.490 1.00 58.00 ? 254 GLU B N 1 ATOM 5116 C CA . GLU B 1 254 ? 23.127 -33.420 12.179 1.00 53.53 ? 254 GLU B CA 1 ATOM 5117 C C . GLU B 1 254 ? 24.490 -33.000 11.644 1.00 55.39 ? 254 GLU B C 1 ATOM 5118 O O . GLU B 1 254 ? 24.835 -33.314 10.501 1.00 57.80 ? 254 GLU B O 1 ATOM 5119 C CB . GLU B 1 254 ? 22.910 -34.921 11.996 1.00 56.08 ? 254 GLU B CB 1 ATOM 5120 C CG . GLU B 1 254 ? 21.638 -35.442 12.638 1.00 61.61 ? 254 GLU B CG 1 ATOM 5121 C CD . GLU B 1 254 ? 21.513 -36.946 12.551 1.00 64.25 ? 254 GLU B CD 1 ATOM 5122 O OE1 . GLU B 1 254 ? 20.884 -37.441 11.592 1.00 66.27 ? 254 GLU B OE1 1 ATOM 5123 O OE2 . GLU B 1 254 ? 22.054 -37.635 13.440 1.00 65.10 ? 254 GLU B OE2 1 ATOM 5124 N N . LEU B 1 255 ? 25.269 -32.307 12.480 1.00 53.74 ? 255 LEU B N 1 ATOM 5125 C CA . LEU B 1 255 ? 26.595 -31.855 12.066 1.00 58.52 ? 255 LEU B CA 1 ATOM 5126 C C . LEU B 1 255 ? 27.509 -33.019 11.712 1.00 63.33 ? 255 LEU B C 1 ATOM 5127 O O . LEU B 1 255 ? 28.431 -32.859 10.902 1.00 59.70 ? 255 LEU B O 1 ATOM 5128 C CB . LEU B 1 255 ? 27.238 -31.025 13.173 1.00 56.60 ? 255 LEU B CB 1 ATOM 5129 C CG . LEU B 1 255 ? 26.610 -29.671 13.468 1.00 58.71 ? 255 LEU B CG 1 ATOM 5130 C CD1 . LEU B 1 255 ? 27.107 -29.157 14.803 1.00 50.35 ? 255 LEU B CD1 1 ATOM 5131 C CD2 . LEU B 1 255 ? 26.953 -28.699 12.352 1.00 60.77 ? 255 LEU B CD2 1 ATOM 5132 N N . SER B 1 256 ? 27.278 -34.188 12.318 1.00 60.50 ? 256 SER B N 1 ATOM 5133 C CA . SER B 1 256 ? 28.129 -35.346 12.065 1.00 60.65 ? 256 SER B CA 1 ATOM 5134 C C . SER B 1 256 ? 28.006 -35.829 10.626 1.00 63.47 ? 256 SER B C 1 ATOM 5135 O O . SER B 1 256 ? 28.936 -36.452 10.101 1.00 69.10 ? 256 SER B O 1 ATOM 5136 C CB . SER B 1 256 ? 27.782 -36.473 13.041 1.00 56.05 ? 256 SER B CB 1 ATOM 5137 O OG . SER B 1 256 ? 26.469 -36.962 12.823 1.00 61.38 ? 256 SER B OG 1 ATOM 5138 N N . ASN B 1 257 ? 26.875 -35.549 9.975 1.00 61.48 ? 257 ASN B N 1 ATOM 5139 C CA . ASN B 1 257 ? 26.674 -35.903 8.576 1.00 58.89 ? 257 ASN B CA 1 ATOM 5140 C C . ASN B 1 257 ? 27.362 -34.947 7.615 1.00 62.79 ? 257 ASN B C 1 ATOM 5141 O O . ASN B 1 257 ? 27.366 -35.210 6.407 1.00 63.40 ? 257 ASN B O 1 ATOM 5142 C CB . ASN B 1 257 ? 25.181 -35.941 8.246 1.00 56.98 ? 257 ASN B CB 1 ATOM 5143 C CG . ASN B 1 257 ? 24.423 -36.939 9.092 1.00 63.69 ? 257 ASN B CG 1 ATOM 5144 O OD1 . ASN B 1 257 ? 25.020 -37.756 9.795 1.00 64.04 ? 257 ASN B OD1 1 ATOM 5145 N ND2 . ASN B 1 257 ? 23.098 -36.884 9.024 1.00 60.64 ? 257 ASN B ND2 1 ATOM 5146 N N . TYR B 1 258 ? 27.928 -33.852 8.106 1.00 56.14 ? 258 TYR B N 1 ATOM 5147 C CA . TYR B 1 258 ? 28.546 -32.860 7.241 1.00 60.44 ? 258 TYR B CA 1 ATOM 5148 C C . TYR B 1 258 ? 29.996 -32.573 7.582 1.00 63.57 ? 258 TYR B C 1 ATOM 5149 O O . TYR B 1 258 ? 30.754 -32.188 6.693 1.00 64.78 ? 258 TYR B O 1 ATOM 5150 C CB . TYR B 1 258 ? 27.747 -31.548 7.281 1.00 56.90 ? 258 TYR B CB 1 ATOM 5151 C CG . TYR B 1 258 ? 26.304 -31.716 6.862 1.00 61.59 ? 258 TYR B CG 1 ATOM 5152 C CD1 . TYR B 1 258 ? 25.929 -31.595 5.531 1.00 64.87 ? 258 TYR B CD1 1 ATOM 5153 C CD2 . TYR B 1 258 ? 25.316 -32.001 7.797 1.00 60.70 ? 258 TYR B CD2 1 ATOM 5154 C CE1 . TYR B 1 258 ? 24.605 -31.748 5.142 1.00 65.89 ? 258 TYR B CE1 1 ATOM 5155 C CE2 . TYR B 1 258 ? 23.991 -32.159 7.418 1.00 60.00 ? 258 TYR B CE2 1 ATOM 5156 C CZ . TYR B 1 258 ? 23.643 -32.032 6.089 1.00 63.82 ? 258 TYR B CZ 1 ATOM 5157 O OH . TYR B 1 258 ? 22.329 -32.187 5.704 1.00 70.35 ? 258 TYR B OH 1 ATOM 5158 N N . ILE B 1 259 ? 30.404 -32.752 8.837 1.00 65.51 ? 259 ILE B N 1 ATOM 5159 C CA . ILE B 1 259 ? 31.791 -32.593 9.251 1.00 65.72 ? 259 ILE B CA 1 ATOM 5160 C C . ILE B 1 259 ? 32.108 -33.658 10.292 1.00 66.81 ? 259 ILE B C 1 ATOM 5161 O O . ILE B 1 259 ? 31.220 -34.336 10.815 1.00 64.92 ? 259 ILE B O 1 ATOM 5162 C CB . ILE B 1 259 ? 32.088 -31.186 9.817 1.00 63.50 ? 259 ILE B CB 1 ATOM 5163 C CG1 . ILE B 1 259 ? 31.044 -30.797 10.867 1.00 62.60 ? 259 ILE B CG1 1 ATOM 5164 C CG2 . ILE B 1 259 ? 32.152 -30.155 8.701 1.00 61.95 ? 259 ILE B CG2 1 ATOM 5165 C CD1 . ILE B 1 259 ? 31.390 -29.537 11.627 1.00 61.76 ? 259 ILE B CD1 1 ATOM 5166 N N . SER B 1 260 ? 33.400 -33.804 10.580 1.00 66.40 ? 260 SER B N 1 ATOM 5167 C CA . SER B 1 260 ? 33.864 -34.677 11.648 1.00 69.24 ? 260 SER B CA 1 ATOM 5168 C C . SER B 1 260 ? 33.946 -33.885 12.945 1.00 65.60 ? 260 SER B C 1 ATOM 5169 O O . SER B 1 260 ? 34.587 -32.829 12.993 1.00 61.48 ? 260 SER B O 1 ATOM 5170 C CB . SER B 1 260 ? 35.229 -35.279 11.311 1.00 70.94 ? 260 SER B CB 1 ATOM 5171 O OG . SER B 1 260 ? 35.841 -35.833 12.466 1.00 70.29 ? 260 SER B OG 1 ATOM 5172 N N . LEU B 1 261 ? 33.289 -34.396 13.990 1.00 69.88 ? 261 LEU B N 1 ATOM 5173 C CA . LEU B 1 261 ? 33.335 -33.731 15.289 1.00 68.68 ? 261 LEU B CA 1 ATOM 5174 C C . LEU B 1 261 ? 34.765 -33.582 15.780 1.00 71.36 ? 261 LEU B C 1 ATOM 5175 O O . LEU B 1 261 ? 35.084 -32.619 16.488 1.00 66.42 ? 261 LEU B O 1 ATOM 5176 C CB . LEU B 1 261 ? 32.510 -34.511 16.312 1.00 68.62 ? 261 LEU B CB 1 ATOM 5177 C CG . LEU B 1 261 ? 31.118 -34.981 15.888 1.00 69.32 ? 261 LEU B CG 1 ATOM 5178 C CD1 . LEU B 1 261 ? 30.508 -35.870 16.965 1.00 68.35 ? 261 LEU B CD1 1 ATOM 5179 C CD2 . LEU B 1 261 ? 30.214 -33.793 15.580 1.00 68.07 ? 261 LEU B CD2 1 ATOM 5180 N N . ASP B 1 262 ? 35.637 -34.525 15.404 1.00 71.65 ? 262 ASP B N 1 ATOM 5181 C CA . ASP B 1 262 ? 37.044 -34.472 15.784 1.00 70.59 ? 262 ASP B CA 1 ATOM 5182 C C . ASP B 1 262 ? 37.700 -33.175 15.336 1.00 62.35 ? 262 ASP B C 1 ATOM 5183 O O . ASP B 1 262 ? 38.693 -32.741 15.930 1.00 61.63 ? 262 ASP B O 1 ATOM 5184 C CB . ASP B 1 262 ? 37.778 -35.676 15.184 1.00 70.07 ? 262 ASP B CB 1 ATOM 5185 C CG . ASP B 1 262 ? 38.854 -36.222 16.099 1.00 71.07 ? 262 ASP B CG 1 ATOM 5186 O OD1 . ASP B 1 262 ? 39.584 -35.416 16.713 1.00 78.21 ? 262 ASP B OD1 1 ATOM 5187 O OD2 . ASP B 1 262 ? 38.966 -37.462 16.208 1.00 66.45 ? 262 ASP B OD2 1 ATOM 5188 N N . ASP B 1 263 ? 37.160 -32.544 14.299 1.00 64.94 ? 263 ASP B N 1 ATOM 5189 C CA . ASP B 1 263 ? 37.675 -31.284 13.787 1.00 66.69 ? 263 ASP B CA 1 ATOM 5190 C C . ASP B 1 263 ? 37.252 -30.087 14.624 1.00 69.71 ? 263 ASP B C 1 ATOM 5191 O O . ASP B 1 263 ? 37.518 -28.949 14.223 1.00 67.57 ? 263 ASP B O 1 ATOM 5192 C CB . ASP B 1 263 ? 37.218 -31.083 12.340 1.00 69.62 ? 263 ASP B CB 1 ATOM 5193 C CG . ASP B 1 263 ? 37.610 -32.238 11.439 1.00 72.40 ? 263 ASP B CG 1 ATOM 5194 O OD1 . ASP B 1 263 ? 38.710 -32.797 11.640 1.00 71.32 ? 263 ASP B OD1 1 ATOM 5195 O OD2 . ASP B 1 263 ? 36.822 -32.586 10.533 1.00 72.93 ? 263 ASP B OD2 1 ATOM 5196 N N . LEU B 1 264 ? 36.609 -30.309 15.769 1.00 67.80 ? 264 LEU B N 1 ATOM 5197 C CA . LEU B 1 264 ? 36.047 -29.231 16.574 1.00 68.34 ? 264 LEU B CA 1 ATOM 5198 C C . LEU B 1 264 ? 36.725 -29.188 17.936 1.00 63.51 ? 264 LEU B C 1 ATOM 5199 O O . LEU B 1 264 ? 36.674 -30.162 18.695 1.00 63.51 ? 264 LEU B O 1 ATOM 5200 C CB . LEU B 1 264 ? 34.534 -29.395 16.724 1.00 60.21 ? 264 LEU B CB 1 ATOM 5201 C CG . LEU B 1 264 ? 33.750 -29.078 15.451 1.00 60.62 ? 264 LEU B CG 1 ATOM 5202 C CD1 . LEU B 1 264 ? 32.267 -29.319 15.657 1.00 63.84 ? 264 LEU B CD1 1 ATOM 5203 C CD2 . LEU B 1 264 ? 34.011 -27.644 15.002 1.00 61.15 ? 264 LEU B CD2 1 ATOM 5204 N N . GLN B 1 265 ? 37.358 -28.054 18.233 1.00 62.72 ? 265 GLN B N 1 ATOM 5205 C CA . GLN B 1 265 ? 37.920 -27.814 19.557 1.00 59.74 ? 265 GLN B CA 1 ATOM 5206 C C . GLN B 1 265 ? 36.824 -27.801 20.620 1.00 60.83 ? 265 GLN B C 1 ATOM 5207 O O . GLN B 1 265 ? 36.957 -28.421 21.681 1.00 48.80 ? 265 GLN B O 1 ATOM 5208 C CB . GLN B 1 265 ? 38.680 -26.487 19.530 1.00 56.78 ? 265 GLN B CB 1 ATOM 5209 C CG . GLN B 1 265 ? 39.651 -26.230 20.653 1.00 61.83 ? 265 GLN B CG 1 ATOM 5210 C CD . GLN B 1 265 ? 40.276 -24.847 20.537 1.00 68.16 ? 265 GLN B CD 1 ATOM 5211 O OE1 . GLN B 1 265 ? 39.938 -24.077 19.635 1.00 66.53 ? 265 GLN B OE1 1 ATOM 5212 N NE2 . GLN B 1 265 ? 41.188 -24.526 21.449 1.00 73.90 ? 265 GLN B NE2 1 ATOM 5213 N N . GLN B 1 266 ? 35.720 -27.112 20.342 1.00 58.08 ? 266 GLN B N 1 ATOM 5214 C CA . GLN B 1 266 ? 34.651 -26.942 21.316 1.00 54.71 ? 266 GLN B CA 1 ATOM 5215 C C . GLN B 1 266 ? 33.359 -26.615 20.576 1.00 50.38 ? 266 GLN B C 1 ATOM 5216 O O . GLN B 1 266 ? 33.377 -25.881 19.584 1.00 47.69 ? 266 GLN B O 1 ATOM 5217 C CB . GLN B 1 266 ? 35.007 -25.833 22.319 1.00 51.12 ? 266 GLN B CB 1 ATOM 5218 C CG . GLN B 1 266 ? 33.957 -25.538 23.379 1.00 49.37 ? 266 GLN B CG 1 ATOM 5219 C CD . GLN B 1 266 ? 33.820 -26.643 24.402 1.00 46.49 ? 266 GLN B CD 1 ATOM 5220 O OE1 . GLN B 1 266 ? 33.188 -27.671 24.144 1.00 46.38 ? 266 GLN B OE1 1 ATOM 5221 N NE2 . GLN B 1 266 ? 34.398 -26.431 25.581 1.00 48.70 ? 266 GLN B NE2 1 ATOM 5222 N N . VAL B 1 267 ? 32.251 -27.184 21.050 1.00 48.76 ? 267 VAL B N 1 ATOM 5223 C CA . VAL B 1 267 ? 30.915 -26.878 20.548 1.00 50.93 ? 267 VAL B CA 1 ATOM 5224 C C . VAL B 1 267 ? 30.007 -26.626 21.746 1.00 50.82 ? 267 VAL B C 1 ATOM 5225 O O . VAL B 1 267 ? 30.080 -27.342 22.750 1.00 45.98 ? 267 VAL B O 1 ATOM 5226 C CB . VAL B 1 267 ? 30.364 -28.015 19.657 1.00 50.03 ? 267 VAL B CB 1 ATOM 5227 C CG1 . VAL B 1 267 ? 30.456 -29.356 20.376 1.00 57.34 ? 267 VAL B CG1 1 ATOM 5228 C CG2 . VAL B 1 267 ? 28.924 -27.731 19.232 1.00 48.90 ? 267 VAL B CG2 1 ATOM 5229 N N . LYS B 1 268 ? 29.161 -25.598 21.652 1.00 42.14 ? 268 LYS B N 1 ATOM 5230 C CA . LYS B 1 268 ? 28.276 -25.236 22.754 1.00 40.55 ? 268 LYS B CA 1 ATOM 5231 C C . LYS B 1 268 ? 26.839 -25.102 22.265 1.00 40.16 ? 268 LYS B C 1 ATOM 5232 O O . LYS B 1 268 ? 26.580 -24.467 21.235 1.00 40.68 ? 268 LYS B O 1 ATOM 5233 C CB . LYS B 1 268 ? 28.736 -23.938 23.431 1.00 40.77 ? 268 LYS B CB 1 ATOM 5234 C CG . LYS B 1 268 ? 29.941 -24.111 24.360 1.00 37.70 ? 268 LYS B CG 1 ATOM 5235 C CD . LYS B 1 268 ? 29.645 -25.107 25.479 1.00 41.73 ? 268 LYS B CD 1 ATOM 5236 C CE . LYS B 1 268 ? 30.868 -25.329 26.365 1.00 44.82 ? 268 LYS B CE 1 ATOM 5237 N NZ . LYS B 1 268 ? 30.664 -26.446 27.335 1.00 39.38 ? 268 LYS B NZ 1 ATOM 5238 N N . ASP B 1 269 ? 25.923 -25.733 23.004 1.00 33.57 ? 269 ASP B N 1 ATOM 5239 C CA . ASP B 1 269 ? 24.476 -25.683 22.811 1.00 35.23 ? 269 ASP B CA 1 ATOM 5240 C C . ASP B 1 269 ? 24.007 -26.468 21.589 1.00 46.04 ? 269 ASP B C 1 ATOM 5241 O O . ASP B 1 269 ? 24.791 -26.771 20.682 1.00 45.72 ? 269 ASP B O 1 ATOM 5242 C CB . ASP B 1 269 ? 23.985 -24.234 22.714 1.00 33.15 ? 269 ASP B CB 1 ATOM 5243 C CG . ASP B 1 269 ? 22.624 -24.046 23.342 1.00 34.44 ? 269 ASP B CG 1 ATOM 5244 O OD1 . ASP B 1 269 ? 21.924 -25.060 23.561 1.00 36.50 ? 269 ASP B OD1 1 ATOM 5245 O OD2 . ASP B 1 269 ? 22.252 -22.888 23.627 1.00 37.45 ? 269 ASP B OD2 1 ATOM 5246 N N . ARG B 1 270 ? 22.724 -26.823 21.588 1.00 38.08 ? 270 ARG B N 1 ATOM 5247 C CA . ARG B 1 270 ? 22.059 -27.490 20.481 1.00 39.87 ? 270 ARG B CA 1 ATOM 5248 C C . ARG B 1 270 ? 20.702 -26.835 20.296 1.00 46.54 ? 270 ARG B C 1 ATOM 5249 O O . ARG B 1 270 ? 20.099 -26.351 21.257 1.00 43.15 ? 270 ARG B O 1 ATOM 5250 C CB . ARG B 1 270 ? 21.853 -28.990 20.730 1.00 47.97 ? 270 ARG B CB 1 ATOM 5251 C CG . ARG B 1 270 ? 23.055 -29.730 21.284 1.00 54.30 ? 270 ARG B CG 1 ATOM 5252 C CD . ARG B 1 270 ? 22.684 -31.178 21.554 1.00 62.14 ? 270 ARG B CD 1 ATOM 5253 N NE . ARG B 1 270 ? 23.804 -31.967 22.059 1.00 70.14 ? 270 ARG B NE 1 ATOM 5254 C CZ . ARG B 1 270 ? 24.128 -32.062 23.343 1.00 70.56 ? 270 ARG B CZ 1 ATOM 5255 N NH1 . ARG B 1 270 ? 23.418 -31.410 24.255 1.00 72.68 ? 270 ARG B NH1 1 ATOM 5256 N NH2 . ARG B 1 270 ? 25.162 -32.806 23.717 1.00 67.67 ? 270 ARG B NH2 1 ATOM 5257 N N . GLY B 1 271 ? 20.218 -26.840 19.063 1.00 42.07 ? 271 GLY B N 1 ATOM 5258 C CA . GLY B 1 271 ? 18.963 -26.204 18.755 1.00 44.00 ? 271 GLY B CA 1 ATOM 5259 C C . GLY B 1 271 ? 19.116 -25.151 17.679 1.00 41.02 ? 271 GLY B C 1 ATOM 5260 O O . GLY B 1 271 ? 19.649 -25.412 16.598 1.00 38.30 ? 271 GLY B O 1 ATOM 5261 N N . PRO B 1 272 ? 18.640 -23.933 17.950 1.00 39.21 ? 272 PRO B N 1 ATOM 5262 C CA . PRO B 1 272 ? 18.650 -22.903 16.904 1.00 35.54 ? 272 PRO B CA 1 ATOM 5263 C C . PRO B 1 272 ? 19.965 -22.154 16.773 1.00 34.26 ? 272 PRO B C 1 ATOM 5264 O O . PRO B 1 272 ? 20.258 -21.638 15.691 1.00 36.16 ? 272 PRO B O 1 ATOM 5265 C CB . PRO B 1 272 ? 17.519 -21.961 17.338 1.00 33.54 ? 272 PRO B CB 1 ATOM 5266 C CG . PRO B 1 272 ? 17.503 -22.081 18.814 1.00 41.16 ? 272 PRO B CG 1 ATOM 5267 C CD . PRO B 1 272 ? 17.854 -23.518 19.126 1.00 38.10 ? 272 PRO B CD 1 ATOM 5268 N N . VAL B 1 273 ? 20.758 -22.053 17.840 1.00 29.95 ? 273 VAL B N 1 ATOM 5269 C CA . VAL B 1 273 ? 21.960 -21.220 17.819 1.00 32.78 ? 273 VAL B CA 1 ATOM 5270 C C . VAL B 1 273 ? 23.099 -21.995 18.477 1.00 37.09 ? 273 VAL B C 1 ATOM 5271 O O . VAL B 1 273 ? 23.101 -22.183 19.699 1.00 35.52 ? 273 VAL B O 1 ATOM 5272 C CB . VAL B 1 273 ? 21.751 -19.869 18.521 1.00 32.77 ? 273 VAL B CB 1 ATOM 5273 C CG1 . VAL B 1 273 ? 23.014 -19.035 18.449 1.00 29.72 ? 273 VAL B CG1 1 ATOM 5274 C CG2 . VAL B 1 273 ? 20.555 -19.102 17.896 1.00 31.79 ? 273 VAL B CG2 1 ATOM 5275 N N . VAL B 1 274 ? 24.080 -22.416 17.677 1.00 35.49 ? 274 VAL B N 1 ATOM 5276 C CA . VAL B 1 274 ? 25.169 -23.269 18.141 1.00 36.27 ? 274 VAL B CA 1 ATOM 5277 C C . VAL B 1 274 ? 26.500 -22.575 17.892 1.00 37.07 ? 274 VAL B C 1 ATOM 5278 O O . VAL B 1 274 ? 26.724 -21.999 16.822 1.00 40.75 ? 274 VAL B O 1 ATOM 5279 C CB . VAL B 1 274 ? 25.130 -24.648 17.452 1.00 40.27 ? 274 VAL B CB 1 ATOM 5280 C CG1 . VAL B 1 274 ? 26.262 -25.546 17.963 1.00 38.48 ? 274 VAL B CG1 1 ATOM 5281 C CG2 . VAL B 1 274 ? 23.786 -25.297 17.677 1.00 38.53 ? 274 VAL B CG2 1 ATOM 5282 N N . SER B 1 275 ? 27.385 -22.640 18.882 1.00 40.82 ? 275 SER B N 1 ATOM 5283 C CA . SER B 1 275 ? 28.700 -22.020 18.808 1.00 40.41 ? 275 SER B CA 1 ATOM 5284 C C . SER B 1 275 ? 29.748 -23.080 18.490 1.00 42.04 ? 275 SER B C 1 ATOM 5285 O O . SER B 1 275 ? 29.779 -24.141 19.126 1.00 41.19 ? 275 SER B O 1 ATOM 5286 C CB . SER B 1 275 ? 29.036 -21.310 20.120 1.00 42.73 ? 275 SER B CB 1 ATOM 5287 O OG . SER B 1 275 ? 28.207 -20.181 20.314 1.00 36.44 ? 275 SER B OG 1 ATOM 5288 N N . LEU B 1 276 ? 30.595 -22.790 17.506 1.00 42.12 ? 276 LEU B N 1 ATOM 5289 C CA . LEU B 1 276 ? 31.631 -23.708 17.047 1.00 50.99 ? 276 LEU B CA 1 ATOM 5290 C C . LEU B 1 276 ? 33.001 -23.068 17.207 1.00 43.47 ? 276 LEU B C 1 ATOM 5291 O O . LEU B 1 276 ? 33.203 -21.917 16.808 1.00 44.14 ? 276 LEU B O 1 ATOM 5292 C CB . LEU B 1 276 ? 31.421 -24.101 15.582 1.00 43.26 ? 276 LEU B CB 1 ATOM 5293 C CG . LEU B 1 276 ? 30.224 -24.982 15.245 1.00 46.27 ? 276 LEU B CG 1 ATOM 5294 C CD1 . LEU B 1 276 ? 30.319 -25.455 13.808 1.00 44.47 ? 276 LEU B CD1 1 ATOM 5295 C CD2 . LEU B 1 276 ? 30.148 -26.156 16.193 1.00 44.47 ? 276 LEU B CD2 1 ATOM 5296 N N . TRP B 1 277 ? 33.935 -23.821 17.784 1.00 50.81 ? 277 TRP B N 1 ATOM 5297 C CA . TRP B 1 277 ? 35.346 -23.448 17.836 1.00 52.60 ? 277 TRP B CA 1 ATOM 5298 C C . TRP B 1 277 ? 36.137 -24.467 17.029 1.00 59.88 ? 277 TRP B C 1 ATOM 5299 O O . TRP B 1 277 ? 36.393 -25.578 17.518 1.00 57.84 ? 277 TRP B O 1 ATOM 5300 C CB . TRP B 1 277 ? 35.854 -23.400 19.280 1.00 48.12 ? 277 TRP B CB 1 ATOM 5301 C CG . TRP B 1 277 ? 35.350 -22.247 20.076 1.00 46.94 ? 277 TRP B CG 1 ATOM 5302 C CD1 . TRP B 1 277 ? 35.993 -21.064 20.307 1.00 43.08 ? 277 TRP B CD1 1 ATOM 5303 C CD2 . TRP B 1 277 ? 34.099 -22.167 20.767 1.00 40.28 ? 277 TRP B CD2 1 ATOM 5304 N NE1 . TRP B 1 277 ? 35.213 -20.248 21.091 1.00 44.03 ? 277 TRP B NE1 1 ATOM 5305 C CE2 . TRP B 1 277 ? 34.046 -20.902 21.388 1.00 40.95 ? 277 TRP B CE2 1 ATOM 5306 C CE3 . TRP B 1 277 ? 33.019 -23.041 20.921 1.00 41.53 ? 277 TRP B CE3 1 ATOM 5307 C CZ2 . TRP B 1 277 ? 32.955 -20.489 22.154 1.00 39.12 ? 277 TRP B CZ2 1 ATOM 5308 C CZ3 . TRP B 1 277 ? 31.930 -22.626 21.676 1.00 41.08 ? 277 TRP B CZ3 1 ATOM 5309 C CH2 . TRP B 1 277 ? 31.910 -21.363 22.286 1.00 38.62 ? 277 TRP B CH2 1 ATOM 5310 N N . PRO B 1 278 ? 36.535 -24.159 15.798 1.00 64.35 ? 278 PRO B N 1 ATOM 5311 C CA . PRO B 1 278 ? 37.290 -25.139 15.012 1.00 68.41 ? 278 PRO B CA 1 ATOM 5312 C C . PRO B 1 278 ? 38.691 -25.331 15.572 1.00 66.80 ? 278 PRO B C 1 ATOM 5313 O O . PRO B 1 278 ? 39.296 -24.408 16.122 1.00 64.49 ? 278 PRO B O 1 ATOM 5314 C CB . PRO B 1 278 ? 37.331 -24.514 13.613 1.00 65.52 ? 278 PRO B CB 1 ATOM 5315 C CG . PRO B 1 278 ? 37.246 -23.033 13.874 1.00 68.27 ? 278 PRO B CG 1 ATOM 5316 C CD . PRO B 1 278 ? 36.349 -22.885 15.077 1.00 61.39 ? 278 PRO B CD 1 ATOM 5317 N N . VAL B 1 279 ? 39.203 -26.552 15.440 1.00 70.60 ? 279 VAL B N 1 ATOM 5318 C CA . VAL B 1 279 ? 40.607 -26.797 15.768 1.00 74.79 ? 279 VAL B CA 1 ATOM 5319 C C . VAL B 1 279 ? 41.430 -25.946 14.810 1.00 72.53 ? 279 VAL B C 1 ATOM 5320 O O . VAL B 1 279 ? 40.985 -25.693 13.681 1.00 74.91 ? 279 VAL B O 1 ATOM 5321 C CB . VAL B 1 279 ? 40.980 -28.288 15.675 1.00 71.37 ? 279 VAL B CB 1 ATOM 5322 C CG1 . VAL B 1 279 ? 40.301 -29.085 16.780 1.00 69.37 ? 279 VAL B CG1 1 ATOM 5323 C CG2 . VAL B 1 279 ? 40.634 -28.851 14.305 1.00 71.18 ? 279 VAL B CG2 1 ATOM 5324 N N . PRO B 1 280 ? 42.604 -25.464 15.212 1.00 71.85 ? 280 PRO B N 1 ATOM 5325 C CA . PRO B 1 280 ? 43.375 -24.578 14.330 1.00 75.93 ? 280 PRO B CA 1 ATOM 5326 C C . PRO B 1 280 ? 43.725 -25.271 13.019 1.00 78.37 ? 280 PRO B C 1 ATOM 5327 O O . PRO B 1 280 ? 44.218 -26.401 13.005 1.00 72.10 ? 280 PRO B O 1 ATOM 5328 C CB . PRO B 1 280 ? 44.626 -24.254 15.156 1.00 75.39 ? 280 PRO B CB 1 ATOM 5329 C CG . PRO B 1 280 ? 44.244 -24.554 16.577 1.00 75.83 ? 280 PRO B CG 1 ATOM 5330 C CD . PRO B 1 280 ? 43.290 -25.706 16.492 1.00 73.07 ? 280 PRO B CD 1 ATOM 5331 N N . GLY B 1 281 ? 43.443 -24.590 11.909 1.00 78.02 ? 281 GLY B N 1 ATOM 5332 C CA . GLY B 1 281 ? 43.721 -25.123 10.593 1.00 73.23 ? 281 GLY B CA 1 ATOM 5333 C C . GLY B 1 281 ? 42.544 -25.759 9.886 1.00 72.85 ? 281 GLY B C 1 ATOM 5334 O O . GLY B 1 281 ? 42.680 -26.142 8.718 1.00 71.29 ? 281 GLY B O 1 ATOM 5335 N N . LYS B 1 282 ? 41.398 -25.896 10.551 1.00 73.51 ? 282 LYS B N 1 ATOM 5336 C CA . LYS B 1 282 ? 40.190 -26.394 9.905 1.00 74.13 ? 282 LYS B CA 1 ATOM 5337 C C . LYS B 1 282 ? 39.089 -25.339 9.890 1.00 70.98 ? 282 LYS B C 1 ATOM 5338 O O . LYS B 1 282 ? 37.921 -25.665 9.650 1.00 66.70 ? 282 LYS B O 1 ATOM 5339 C CB . LYS B 1 282 ? 39.707 -27.680 10.579 1.00 75.17 ? 282 LYS B CB 1 ATOM 5340 C CG . LYS B 1 282 ? 40.762 -28.779 10.613 1.00 70.39 ? 282 LYS B CG 1 ATOM 5341 C CD . LYS B 1 282 ? 40.156 -30.158 10.396 1.00 70.83 ? 282 LYS B CD 1 ATOM 5342 C CE . LYS B 1 282 ? 39.565 -30.303 8.998 1.00 75.38 ? 282 LYS B CE 1 ATOM 5343 N NZ . LYS B 1 282 ? 39.345 -31.732 8.622 1.00 72.66 ? 282 LYS B NZ 1 ATOM 5344 N N . HIS B 1 283 ? 39.453 -24.078 10.140 1.00 62.79 ? 283 HIS B N 1 ATOM 5345 C CA . HIS B 1 283 ? 38.492 -22.982 10.124 1.00 63.83 ? 283 HIS B CA 1 ATOM 5346 C C . HIS B 1 283 ? 37.756 -22.923 8.790 1.00 68.17 ? 283 HIS B C 1 ATOM 5347 O O . HIS B 1 283 ? 36.524 -23.020 8.736 1.00 61.00 ? 283 HIS B O 1 ATOM 5348 C CB . HIS B 1 283 ? 39.226 -21.668 10.408 1.00 67.14 ? 283 HIS B CB 1 ATOM 5349 C CG . HIS B 1 283 ? 38.325 -20.505 10.691 1.00 72.94 ? 283 HIS B CG 1 ATOM 5350 N ND1 . HIS B 1 283 ? 37.964 -19.590 9.725 1.00 74.05 ? 283 HIS B ND1 1 ATOM 5351 C CD2 . HIS B 1 283 ? 37.735 -20.092 11.838 1.00 70.62 ? 283 HIS B CD2 1 ATOM 5352 C CE1 . HIS B 1 283 ? 37.180 -18.672 10.262 1.00 70.84 ? 283 HIS B CE1 1 ATOM 5353 N NE2 . HIS B 1 283 ? 37.026 -18.953 11.543 1.00 68.65 ? 283 HIS B NE2 1 ATOM 5354 N N . SER B 1 284 ? 38.505 -22.795 7.692 1.00 64.94 ? 284 SER B N 1 ATOM 5355 C CA . SER B 1 284 ? 37.873 -22.683 6.384 1.00 61.22 ? 284 SER B CA 1 ATOM 5356 C C . SER B 1 284 ? 37.227 -23.993 5.951 1.00 61.66 ? 284 SER B C 1 ATOM 5357 O O . SER B 1 284 ? 36.222 -23.973 5.231 1.00 58.48 ? 284 SER B O 1 ATOM 5358 C CB . SER B 1 284 ? 38.894 -22.219 5.350 1.00 64.91 ? 284 SER B CB 1 ATOM 5359 O OG . SER B 1 284 ? 39.394 -20.937 5.688 1.00 69.31 ? 284 SER B OG 1 ATOM 5360 N N . GLU B 1 285 ? 37.779 -25.133 6.372 1.00 62.29 ? 285 GLU B N 1 ATOM 5361 C CA . GLU B 1 285 ? 37.180 -26.416 6.015 1.00 69.00 ? 285 GLU B CA 1 ATOM 5362 C C . GLU B 1 285 ? 35.786 -26.542 6.615 1.00 65.93 ? 285 GLU B C 1 ATOM 5363 O O . GLU B 1 285 ? 34.806 -26.781 5.899 1.00 61.50 ? 285 GLU B O 1 ATOM 5364 C CB . GLU B 1 285 ? 38.079 -27.569 6.472 1.00 70.36 ? 285 GLU B CB 1 ATOM 5365 C CG . GLU B 1 285 ? 37.690 -28.941 5.908 1.00 70.53 ? 285 GLU B CG 1 ATOM 5366 C CD . GLU B 1 285 ? 36.729 -29.714 6.802 1.00 78.78 ? 285 GLU B CD 1 ATOM 5367 O OE1 . GLU B 1 285 ? 36.513 -29.293 7.957 1.00 81.37 ? 285 GLU B OE1 1 ATOM 5368 O OE2 . GLU B 1 285 ? 36.193 -30.750 6.351 1.00 85.34 ? 285 GLU B OE2 1 ATOM 5369 N N . ILE B 1 286 ? 35.683 -26.377 7.937 1.00 66.38 ? 286 ILE B N 1 ATOM 5370 C CA . ILE B 1 286 ? 34.385 -26.439 8.607 1.00 63.30 ? 286 ILE B CA 1 ATOM 5371 C C . ILE B 1 286 ? 33.440 -25.403 8.017 1.00 59.20 ? 286 ILE B C 1 ATOM 5372 O O . ILE B 1 286 ? 32.300 -25.712 7.651 1.00 58.83 ? 286 ILE B O 1 ATOM 5373 C CB . ILE B 1 286 ? 34.551 -26.245 10.127 1.00 65.38 ? 286 ILE B CB 1 ATOM 5374 C CG1 . ILE B 1 286 ? 35.455 -27.326 10.723 1.00 63.71 ? 286 ILE B CG1 1 ATOM 5375 C CG2 . ILE B 1 286 ? 33.194 -26.248 10.818 1.00 58.06 ? 286 ILE B CG2 1 ATOM 5376 C CD1 . ILE B 1 286 ? 34.843 -28.705 10.726 1.00 61.58 ? 286 ILE B CD1 1 ATOM 5377 N N . TYR B 1 287 ? 33.911 -24.159 7.900 1.00 53.70 ? 287 TYR B N 1 ATOM 5378 C CA . TYR B 1 287 ? 33.060 -23.074 7.422 1.00 57.35 ? 287 TYR B CA 1 ATOM 5379 C C . TYR B 1 287 ? 32.472 -23.392 6.053 1.00 61.32 ? 287 TYR B C 1 ATOM 5380 O O . TYR B 1 287 ? 31.251 -23.501 5.898 1.00 55.44 ? 287 TYR B O 1 ATOM 5381 C CB . TYR B 1 287 ? 33.855 -21.769 7.380 1.00 55.61 ? 287 TYR B CB 1 ATOM 5382 C CG . TYR B 1 287 ? 33.082 -20.609 6.798 1.00 60.98 ? 287 TYR B CG 1 ATOM 5383 C CD1 . TYR B 1 287 ? 32.095 -19.969 7.534 1.00 61.25 ? 287 TYR B CD1 1 ATOM 5384 C CD2 . TYR B 1 287 ? 33.342 -20.153 5.514 1.00 62.38 ? 287 TYR B CD2 1 ATOM 5385 C CE1 . TYR B 1 287 ? 31.386 -18.906 7.009 1.00 62.17 ? 287 TYR B CE1 1 ATOM 5386 C CE2 . TYR B 1 287 ? 32.640 -19.091 4.978 1.00 66.09 ? 287 TYR B CE2 1 ATOM 5387 C CZ . TYR B 1 287 ? 31.664 -18.469 5.730 1.00 67.68 ? 287 TYR B CZ 1 ATOM 5388 O OH . TYR B 1 287 ? 30.960 -17.411 5.200 1.00 69.04 ? 287 TYR B OH 1 ATOM 5389 N N . HIS B 1 288 ? 33.335 -23.573 5.048 1.00 58.10 ? 288 HIS B N 1 ATOM 5390 C CA . HIS B 1 288 ? 32.855 -23.792 3.687 1.00 55.96 ? 288 HIS B CA 1 ATOM 5391 C C . HIS B 1 288 ? 32.064 -25.088 3.560 1.00 57.84 ? 288 HIS B C 1 ATOM 5392 O O . HIS B 1 288 ? 31.198 -25.198 2.684 1.00 60.38 ? 288 HIS B O 1 ATOM 5393 C CB . HIS B 1 288 ? 34.032 -23.776 2.715 1.00 60.30 ? 288 HIS B CB 1 ATOM 5394 C CG . HIS B 1 288 ? 34.569 -22.405 2.449 1.00 63.40 ? 288 HIS B CG 1 ATOM 5395 N ND1 . HIS B 1 288 ? 33.751 -21.312 2.257 1.00 66.68 ? 288 HIS B ND1 1 ATOM 5396 C CD2 . HIS B 1 288 ? 35.839 -21.944 2.357 1.00 61.80 ? 288 HIS B CD2 1 ATOM 5397 C CE1 . HIS B 1 288 ? 34.492 -20.240 2.046 1.00 63.26 ? 288 HIS B CE1 1 ATOM 5398 N NE2 . HIS B 1 288 ? 35.763 -20.595 2.103 1.00 63.34 ? 288 HIS B NE2 1 ATOM 5399 N N . LYS B 1 289 ? 32.331 -26.069 4.421 1.00 54.39 ? 289 LYS B N 1 ATOM 5400 C CA . LYS B 1 289 ? 31.535 -27.290 4.399 1.00 58.27 ? 289 LYS B CA 1 ATOM 5401 C C . LYS B 1 289 ? 30.116 -27.040 4.903 1.00 61.21 ? 289 LYS B C 1 ATOM 5402 O O . LYS B 1 289 ? 29.148 -27.564 4.339 1.00 61.44 ? 289 LYS B O 1 ATOM 5403 C CB . LYS B 1 289 ? 32.212 -28.373 5.233 1.00 59.01 ? 289 LYS B CB 1 ATOM 5404 C CG . LYS B 1 289 ? 31.567 -29.728 5.086 1.00 64.82 ? 289 LYS B CG 1 ATOM 5405 C CD . LYS B 1 289 ? 31.490 -30.133 3.618 1.00 70.10 ? 289 LYS B CD 1 ATOM 5406 C CE . LYS B 1 289 ? 31.046 -31.579 3.450 1.00 65.72 ? 289 LYS B CE 1 ATOM 5407 N NZ . LYS B 1 289 ? 29.617 -31.690 3.047 1.00 64.02 ? 289 LYS B NZ 1 ATOM 5408 N N . LEU B 1 290 ? 29.969 -26.245 5.961 1.00 61.38 ? 290 LEU B N 1 ATOM 5409 C CA . LEU B 1 290 ? 28.650 -26.023 6.539 1.00 59.37 ? 290 LEU B CA 1 ATOM 5410 C C . LEU B 1 290 ? 27.836 -24.984 5.778 1.00 55.72 ? 290 LEU B C 1 ATOM 5411 O O . LEU B 1 290 ? 26.612 -24.940 5.940 1.00 54.11 ? 290 LEU B O 1 ATOM 5412 C CB . LEU B 1 290 ? 28.791 -25.621 8.009 1.00 54.39 ? 290 LEU B CB 1 ATOM 5413 C CG . LEU B 1 290 ? 29.352 -26.715 8.918 1.00 54.24 ? 290 LEU B CG 1 ATOM 5414 C CD1 . LEU B 1 290 ? 29.387 -26.252 10.362 1.00 58.83 ? 290 LEU B CD1 1 ATOM 5415 C CD2 . LEU B 1 290 ? 28.535 -27.992 8.781 1.00 58.92 ? 290 LEU B CD2 1 ATOM 5416 N N . ARG B 1 291 ? 28.482 -24.164 4.943 1.00 57.77 ? 291 ARG B N 1 ATOM 5417 C CA . ARG B 1 291 ? 27.758 -23.209 4.109 1.00 60.16 ? 291 ARG B CA 1 ATOM 5418 C C . ARG B 1 291 ? 26.775 -23.889 3.169 1.00 55.78 ? 291 ARG B C 1 ATOM 5419 O O . ARG B 1 291 ? 25.807 -23.255 2.737 1.00 53.74 ? 291 ARG B O 1 ATOM 5420 C CB . ARG B 1 291 ? 28.737 -22.371 3.287 1.00 55.40 ? 291 ARG B CB 1 ATOM 5421 C CG . ARG B 1 291 ? 29.729 -21.581 4.106 1.00 61.19 ? 291 ARG B CG 1 ATOM 5422 C CD . ARG B 1 291 ? 29.058 -20.452 4.842 1.00 62.18 ? 291 ARG B CD 1 ATOM 5423 N NE . ARG B 1 291 ? 28.332 -19.580 3.927 1.00 74.56 ? 291 ARG B NE 1 ATOM 5424 C CZ . ARG B 1 291 ? 28.027 -18.312 4.183 1.00 76.43 ? 291 ARG B CZ 1 ATOM 5425 N NH1 . ARG B 1 291 ? 28.397 -17.754 5.330 1.00 66.93 ? 291 ARG B NH1 1 ATOM 5426 N NH2 . ARG B 1 291 ? 27.359 -17.597 3.286 1.00 83.26 ? 291 ARG B NH2 1 ATOM 5427 N N . THR B 1 292 ? 27.002 -25.156 2.839 1.00 57.78 ? 292 THR B N 1 ATOM 5428 C CA . THR B 1 292 ? 26.149 -25.865 1.897 1.00 61.82 ? 292 THR B CA 1 ATOM 5429 C C . THR B 1 292 ? 24.931 -26.498 2.553 1.00 60.44 ? 292 THR B C 1 ATOM 5430 O O . THR B 1 292 ? 24.071 -27.029 1.841 1.00 58.82 ? 292 THR B O 1 ATOM 5431 C CB . THR B 1 292 ? 26.950 -26.951 1.170 1.00 61.90 ? 292 THR B CB 1 ATOM 5432 O OG1 . THR B 1 292 ? 27.278 -28.003 2.089 1.00 60.08 ? 292 THR B OG1 1 ATOM 5433 C CG2 . THR B 1 292 ? 28.232 -26.363 0.587 1.00 59.52 ? 292 THR B CG2 1 ATOM 5434 N N . VAL B 1 293 ? 24.831 -26.454 3.877 1.00 59.65 ? 293 VAL B N 1 ATOM 5435 C CA . VAL B 1 293 ? 23.693 -27.049 4.571 1.00 60.74 ? 293 VAL B CA 1 ATOM 5436 C C . VAL B 1 293 ? 22.506 -26.099 4.476 1.00 55.40 ? 293 VAL B C 1 ATOM 5437 O O . VAL B 1 293 ? 22.604 -24.923 4.843 1.00 57.72 ? 293 VAL B O 1 ATOM 5438 C CB . VAL B 1 293 ? 24.037 -27.361 6.033 1.00 53.33 ? 293 VAL B CB 1 ATOM 5439 C CG1 . VAL B 1 293 ? 22.933 -28.204 6.664 1.00 42.64 ? 293 VAL B CG1 1 ATOM 5440 C CG2 . VAL B 1 293 ? 25.385 -28.063 6.119 1.00 54.81 ? 293 VAL B CG2 1 ATOM 5441 N N . GLU B 1 294 ? 21.384 -26.604 3.971 1.00 45.82 ? 294 GLU B N 1 ATOM 5442 C CA . GLU B 1 294 ? 20.188 -25.785 3.880 1.00 56.60 ? 294 GLU B CA 1 ATOM 5443 C C . GLU B 1 294 ? 19.519 -25.677 5.247 1.00 48.01 ? 294 GLU B C 1 ATOM 5444 O O . GLU B 1 294 ? 19.809 -26.436 6.173 1.00 46.86 ? 294 GLU B O 1 ATOM 5445 C CB . GLU B 1 294 ? 19.211 -26.360 2.855 1.00 57.23 ? 294 GLU B CB 1 ATOM 5446 C CG . GLU B 1 294 ? 19.613 -26.132 1.405 1.00 67.12 ? 294 GLU B CG 1 ATOM 5447 C CD . GLU B 1 294 ? 18.497 -26.471 0.428 1.00 77.12 ? 294 GLU B CD 1 ATOM 5448 O OE1 . GLU B 1 294 ? 17.733 -27.426 0.694 1.00 75.60 ? 294 GLU B OE1 1 ATOM 5449 O OE2 . GLU B 1 294 ? 18.377 -25.772 -0.601 1.00 77.23 ? 294 GLU B OE2 1 ATOM 5450 N N . HIS B 1 295 ? 18.619 -24.700 5.364 1.00 48.50 ? 295 HIS B N 1 ATOM 5451 C CA . HIS B 1 295 ? 17.788 -24.484 6.549 1.00 49.74 ? 295 HIS B CA 1 ATOM 5452 C C . HIS B 1 295 ? 18.596 -24.041 7.769 1.00 43.71 ? 295 HIS B C 1 ATOM 5453 O O . HIS B 1 295 ? 18.119 -24.152 8.902 1.00 47.09 ? 295 HIS B O 1 ATOM 5454 C CB . HIS B 1 295 ? 16.957 -25.729 6.883 1.00 49.83 ? 295 HIS B CB 1 ATOM 5455 C CG . HIS B 1 295 ? 16.157 -26.242 5.727 1.00 51.42 ? 295 HIS B CG 1 ATOM 5456 N ND1 . HIS B 1 295 ? 15.047 -25.586 5.241 1.00 52.00 ? 295 HIS B ND1 1 ATOM 5457 C CD2 . HIS B 1 295 ? 16.309 -27.346 4.956 1.00 53.49 ? 295 HIS B CD2 1 ATOM 5458 C CE1 . HIS B 1 295 ? 14.547 -26.266 4.224 1.00 53.80 ? 295 HIS B CE1 1 ATOM 5459 N NE2 . HIS B 1 295 ? 15.293 -27.338 4.032 1.00 51.05 ? 295 HIS B NE2 1 ATOM 5460 N N . MET B 1 296 ? 19.805 -23.532 7.558 1.00 39.93 ? 296 MET B N 1 ATOM 5461 C CA . MET B 1 296 ? 20.539 -22.818 8.593 1.00 43.86 ? 296 MET B CA 1 ATOM 5462 C C . MET B 1 296 ? 21.524 -21.884 7.911 1.00 46.62 ? 296 MET B C 1 ATOM 5463 O O . MET B 1 296 ? 21.703 -21.921 6.692 1.00 47.21 ? 296 MET B O 1 ATOM 5464 C CB . MET B 1 296 ? 21.264 -23.772 9.548 1.00 42.58 ? 296 MET B CB 1 ATOM 5465 C CG . MET B 1 296 ? 22.369 -24.575 8.890 1.00 46.83 ? 296 MET B CG 1 ATOM 5466 S SD . MET B 1 296 ? 23.353 -25.490 10.086 1.00 51.22 ? 296 MET B SD 1 ATOM 5467 C CE . MET B 1 296 ? 24.789 -24.433 10.174 1.00 52.68 ? 296 MET B CE 1 ATOM 5468 N N . THR B 1 297 ? 22.171 -21.048 8.719 1.00 39.39 ? 297 THR B N 1 ATOM 5469 C CA . THR B 1 297 ? 23.178 -20.119 8.236 1.00 39.64 ? 297 THR B CA 1 ATOM 5470 C C . THR B 1 297 ? 24.408 -20.204 9.131 1.00 49.94 ? 297 THR B C 1 ATOM 5471 O O . THR B 1 297 ? 24.290 -20.272 10.360 1.00 41.93 ? 297 THR B O 1 ATOM 5472 C CB . THR B 1 297 ? 22.640 -18.685 8.207 1.00 41.22 ? 297 THR B CB 1 ATOM 5473 O OG1 . THR B 1 297 ? 21.380 -18.661 7.522 1.00 45.50 ? 297 THR B OG1 1 ATOM 5474 C CG2 . THR B 1 297 ? 23.603 -17.769 7.492 1.00 47.40 ? 297 THR B CG2 1 ATOM 5475 N N . VAL B 1 298 ? 25.584 -20.219 8.505 1.00 42.17 ? 298 VAL B N 1 ATOM 5476 C CA . VAL B 1 298 ? 26.865 -20.204 9.204 1.00 45.68 ? 298 VAL B CA 1 ATOM 5477 C C . VAL B 1 298 ? 27.444 -18.803 9.102 1.00 46.69 ? 298 VAL B C 1 ATOM 5478 O O . VAL B 1 298 ? 27.605 -18.271 7.998 1.00 49.68 ? 298 VAL B O 1 ATOM 5479 C CB . VAL B 1 298 ? 27.843 -21.232 8.610 1.00 51.73 ? 298 VAL B CB 1 ATOM 5480 C CG1 . VAL B 1 298 ? 29.017 -21.454 9.557 1.00 50.14 ? 298 VAL B CG1 1 ATOM 5481 C CG2 . VAL B 1 298 ? 27.129 -22.531 8.290 1.00 54.74 ? 298 VAL B CG2 1 ATOM 5482 N N . TYR B 1 299 ? 27.771 -18.210 10.244 1.00 42.40 ? 299 TYR B N 1 ATOM 5483 C CA . TYR B 1 299 ? 28.358 -16.880 10.288 1.00 41.95 ? 299 TYR B CA 1 ATOM 5484 C C . TYR B 1 299 ? 29.759 -16.959 10.864 1.00 50.13 ? 299 TYR B C 1 ATOM 5485 O O . TYR B 1 299 ? 29.958 -17.514 11.951 1.00 48.33 ? 299 TYR B O 1 ATOM 5486 C CB . TYR B 1 299 ? 27.533 -15.920 11.144 1.00 44.78 ? 299 TYR B CB 1 ATOM 5487 C CG . TYR B 1 299 ? 26.145 -15.652 10.633 1.00 44.81 ? 299 TYR B CG 1 ATOM 5488 C CD1 . TYR B 1 299 ? 25.917 -14.692 9.656 1.00 43.64 ? 299 TYR B CD1 1 ATOM 5489 C CD2 . TYR B 1 299 ? 25.057 -16.346 11.140 1.00 42.38 ? 299 TYR B CD2 1 ATOM 5490 C CE1 . TYR B 1 299 ? 24.640 -14.440 9.191 1.00 46.26 ? 299 TYR B CE1 1 ATOM 5491 C CE2 . TYR B 1 299 ? 23.778 -16.098 10.684 1.00 40.05 ? 299 TYR B CE2 1 ATOM 5492 C CZ . TYR B 1 299 ? 23.574 -15.146 9.711 1.00 43.63 ? 299 TYR B CZ 1 ATOM 5493 O OH . TYR B 1 299 ? 22.298 -14.901 9.257 1.00 46.19 ? 299 TYR B OH 1 ATOM 5494 N N . GLU B 1 300 ? 30.723 -16.408 10.137 1.00 48.25 ? 300 GLU B N 1 ATOM 5495 C CA . GLU B 1 300 ? 31.937 -15.947 10.786 1.00 54.32 ? 300 GLU B CA 1 ATOM 5496 C C . GLU B 1 300 ? 31.576 -14.763 11.667 1.00 43.92 ? 300 GLU B C 1 ATOM 5497 O O . GLU B 1 300 ? 30.651 -14.011 11.356 1.00 45.31 ? 300 GLU B O 1 ATOM 5498 C CB . GLU B 1 300 ? 32.991 -15.562 9.751 1.00 51.56 ? 300 GLU B CB 1 ATOM 5499 C CG . GLU B 1 300 ? 34.036 -16.634 9.534 1.00 59.86 ? 300 GLU B CG 1 ATOM 5500 C CD . GLU B 1 300 ? 34.567 -16.648 8.120 1.00 70.57 ? 300 GLU B CD 1 ATOM 5501 O OE1 . GLU B 1 300 ? 33.941 -16.007 7.246 1.00 70.84 ? 300 GLU B OE1 1 ATOM 5502 O OE2 . GLU B 1 300 ? 35.605 -17.303 7.884 1.00 68.18 ? 300 GLU B OE2 1 ATOM 5503 N N . LYS B 1 301 ? 32.292 -14.622 12.788 1.00 45.04 ? 301 LYS B N 1 ATOM 5504 C CA . LYS B 1 301 ? 31.919 -13.644 13.809 1.00 47.01 ? 301 LYS B CA 1 ATOM 5505 C C . LYS B 1 301 ? 31.759 -12.248 13.220 1.00 50.74 ? 301 LYS B C 1 ATOM 5506 O O . LYS B 1 301 ? 30.851 -11.501 13.606 1.00 50.21 ? 301 LYS B O 1 ATOM 5507 C CB . LYS B 1 301 ? 32.961 -13.650 14.933 1.00 50.28 ? 301 LYS B CB 1 ATOM 5508 C CG . LYS B 1 301 ? 32.898 -12.463 15.885 1.00 48.82 ? 301 LYS B CG 1 ATOM 5509 C CD . LYS B 1 301 ? 33.634 -12.760 17.192 1.00 46.52 ? 301 LYS B CD 1 ATOM 5510 C CE . LYS B 1 301 ? 33.848 -11.485 18.009 1.00 54.85 ? 301 LYS B CE 1 ATOM 5511 N NZ . LYS B 1 301 ? 34.343 -11.739 19.399 1.00 57.61 ? 301 LYS B NZ 1 ATOM 5512 N N . GLU B 1 302 ? 32.610 -11.888 12.262 1.00 47.40 ? 302 GLU B N 1 ATOM 5513 C CA . GLU B 1 302 ? 32.532 -10.566 11.657 1.00 48.02 ? 302 GLU B CA 1 ATOM 5514 C C . GLU B 1 302 ? 31.359 -10.433 10.695 1.00 42.36 ? 302 GLU B C 1 ATOM 5515 O O . GLU B 1 302 ? 30.993 -9.309 10.340 1.00 44.41 ? 302 GLU B O 1 ATOM 5516 C CB . GLU B 1 302 ? 33.839 -10.242 10.927 1.00 57.25 ? 302 GLU B CB 1 ATOM 5517 C CG . GLU B 1 302 ? 35.098 -10.378 11.784 1.00 59.40 ? 302 GLU B CG 1 ATOM 5518 C CD . GLU B 1 302 ? 35.496 -11.826 12.050 1.00 62.10 ? 302 GLU B CD 1 ATOM 5519 O OE1 . GLU B 1 302 ? 35.103 -12.720 11.263 1.00 59.64 ? 302 GLU B OE1 1 ATOM 5520 O OE2 . GLU B 1 302 ? 36.194 -12.072 13.057 1.00 66.44 ? 302 GLU B OE2 1 ATOM 5521 N N . SER B 1 303 ? 30.761 -11.545 10.269 1.00 41.52 ? 303 SER B N 1 ATOM 5522 C CA . SER B 1 303 ? 29.639 -11.516 9.339 1.00 43.31 ? 303 SER B CA 1 ATOM 5523 C C . SER B 1 303 ? 28.282 -11.665 10.022 1.00 48.76 ? 303 SER B C 1 ATOM 5524 O O . SER B 1 303 ? 27.251 -11.653 9.337 1.00 39.20 ? 303 SER B O 1 ATOM 5525 C CB . SER B 1 303 ? 29.810 -12.613 8.286 1.00 48.24 ? 303 SER B CB 1 ATOM 5526 O OG . SER B 1 303 ? 31.128 -12.604 7.770 1.00 53.57 ? 303 SER B OG 1 ATOM 5527 N N . ILE B 1 304 ? 28.257 -11.817 11.343 1.00 45.40 ? 304 ILE B N 1 ATOM 5528 C CA . ILE B 1 304 ? 26.987 -11.894 12.077 1.00 43.25 ? 304 ILE B CA 1 ATOM 5529 C C . ILE B 1 304 ? 26.178 -10.628 11.812 1.00 34.64 ? 304 ILE B C 1 ATOM 5530 O O . ILE B 1 304 ? 26.728 -9.516 11.912 1.00 34.86 ? 304 ILE B O 1 ATOM 5531 C CB . ILE B 1 304 ? 27.258 -12.081 13.584 1.00 42.38 ? 304 ILE B CB 1 ATOM 5532 C CG1 . ILE B 1 304 ? 27.980 -13.412 13.825 1.00 37.98 ? 304 ILE B CG1 1 ATOM 5533 C CG2 . ILE B 1 304 ? 25.972 -12.015 14.393 1.00 36.25 ? 304 ILE B CG2 1 ATOM 5534 C CD1 . ILE B 1 304 ? 28.425 -13.619 15.266 1.00 43.09 ? 304 ILE B CD1 1 ATOM 5535 N N . PRO B 1 305 ? 24.891 -10.720 11.473 1.00 34.34 ? 305 PRO B N 1 ATOM 5536 C CA . PRO B 1 305 ? 24.122 -9.507 11.155 1.00 33.89 ? 305 PRO B CA 1 ATOM 5537 C C . PRO B 1 305 ? 24.198 -8.487 12.279 1.00 33.59 ? 305 PRO B C 1 ATOM 5538 O O . PRO B 1 305 ? 24.055 -8.823 13.457 1.00 36.00 ? 305 PRO B O 1 ATOM 5539 C CB . PRO B 1 305 ? 22.692 -10.030 10.970 1.00 36.38 ? 305 PRO B CB 1 ATOM 5540 C CG . PRO B 1 305 ? 22.851 -11.476 10.646 1.00 40.09 ? 305 PRO B CG 1 ATOM 5541 C CD . PRO B 1 305 ? 24.058 -11.933 11.411 1.00 40.11 ? 305 PRO B CD 1 ATOM 5542 N N . ASN B 1 306 ? 24.439 -7.228 11.904 1.00 31.79 ? 306 ASN B N 1 ATOM 5543 C CA . ASN B 1 306 ? 24.584 -6.167 12.896 1.00 31.06 ? 306 ASN B CA 1 ATOM 5544 C C . ASN B 1 306 ? 23.328 -6.018 13.741 1.00 36.40 ? 306 ASN B C 1 ATOM 5545 O O . ASN B 1 306 ? 23.407 -5.692 14.931 1.00 35.55 ? 306 ASN B O 1 ATOM 5546 C CB . ASN B 1 306 ? 24.882 -4.834 12.214 1.00 30.30 ? 306 ASN B CB 1 ATOM 5547 C CG . ASN B 1 306 ? 26.233 -4.802 11.548 1.00 49.12 ? 306 ASN B CG 1 ATOM 5548 O OD1 . ASN B 1 306 ? 26.929 -5.814 11.475 1.00 47.93 ? 306 ASN B OD1 1 ATOM 5549 N ND2 . ASN B 1 306 ? 26.612 -3.628 11.045 1.00 44.31 ? 306 ASN B ND2 1 ATOM 5550 N N . ARG B 1 307 ? 22.157 -6.218 13.131 1.00 32.36 ? 307 ARG B N 1 ATOM 5551 C CA . ARG B 1 307 ? 20.899 -6.038 13.842 1.00 32.07 ? 307 ARG B CA 1 ATOM 5552 C C . ARG B 1 307 ? 20.746 -7.001 15.014 1.00 30.49 ? 307 ARG B C 1 ATOM 5553 O O . ARG B 1 307 ? 19.871 -6.787 15.857 1.00 31.37 ? 307 ARG B O 1 ATOM 5554 C CB . ARG B 1 307 ? 19.718 -6.198 12.882 1.00 31.66 ? 307 ARG B CB 1 ATOM 5555 C CG . ARG B 1 307 ? 19.551 -7.599 12.294 1.00 32.79 ? 307 ARG B CG 1 ATOM 5556 C CD . ARG B 1 307 ? 18.219 -7.679 11.551 1.00 27.05 ? 307 ARG B CD 1 ATOM 5557 N NE . ARG B 1 307 ? 17.993 -8.957 10.877 1.00 27.67 ? 307 ARG B NE 1 ATOM 5558 C CZ . ARG B 1 307 ? 17.303 -9.979 11.382 1.00 33.07 ? 307 ARG B CZ 1 ATOM 5559 N NH1 . ARG B 1 307 ? 16.779 -9.913 12.606 1.00 30.47 ? 307 ARG B NH1 1 ATOM 5560 N NH2 . ARG B 1 307 ? 17.144 -11.079 10.657 1.00 30.28 ? 307 ARG B NH2 1 ATOM 5561 N N . PHE B 1 308 ? 21.578 -8.039 15.098 1.00 34.27 ? 308 PHE B N 1 ATOM 5562 C CA . PHE B 1 308 ? 21.540 -8.943 16.239 1.00 31.85 ? 308 PHE B CA 1 ATOM 5563 C C . PHE B 1 308 ? 22.167 -8.342 17.497 1.00 29.49 ? 308 PHE B C 1 ATOM 5564 O O . PHE B 1 308 ? 21.870 -8.823 18.599 1.00 29.81 ? 308 PHE B O 1 ATOM 5565 C CB . PHE B 1 308 ? 22.233 -10.256 15.881 1.00 26.76 ? 308 PHE B CB 1 ATOM 5566 C CG . PHE B 1 308 ? 21.390 -11.186 15.038 1.00 35.45 ? 308 PHE B CG 1 ATOM 5567 C CD1 . PHE B 1 308 ? 20.040 -10.934 14.828 1.00 32.71 ? 308 PHE B CD1 1 ATOM 5568 C CD2 . PHE B 1 308 ? 21.946 -12.319 14.472 1.00 34.96 ? 308 PHE B CD2 1 ATOM 5569 C CE1 . PHE B 1 308 ? 19.263 -11.800 14.064 1.00 35.54 ? 308 PHE B CE1 1 ATOM 5570 C CE2 . PHE B 1 308 ? 21.183 -13.186 13.711 1.00 35.39 ? 308 PHE B CE2 1 ATOM 5571 C CZ . PHE B 1 308 ? 19.830 -12.921 13.505 1.00 33.38 ? 308 PHE B CZ 1 ATOM 5572 N N . TYR B 1 309 ? 23.010 -7.310 17.357 1.00 30.71 ? 309 TYR B N 1 ATOM 5573 C CA . TYR B 1 309 ? 23.699 -6.650 18.477 1.00 31.59 ? 309 TYR B CA 1 ATOM 5574 C C . TYR B 1 309 ? 24.440 -7.664 19.353 1.00 33.53 ? 309 TYR B C 1 ATOM 5575 O O . TYR B 1 309 ? 24.415 -7.610 20.586 1.00 31.20 ? 309 TYR B O 1 ATOM 5576 C CB . TYR B 1 309 ? 22.728 -5.811 19.301 1.00 32.87 ? 309 TYR B CB 1 ATOM 5577 C CG . TYR B 1 309 ? 22.254 -4.583 18.551 1.00 34.36 ? 309 TYR B CG 1 ATOM 5578 C CD1 . TYR B 1 309 ? 23.087 -3.481 18.400 1.00 36.49 ? 309 TYR B CD1 1 ATOM 5579 C CD2 . TYR B 1 309 ? 20.992 -4.536 17.977 1.00 37.95 ? 309 TYR B CD2 1 ATOM 5580 C CE1 . TYR B 1 309 ? 22.676 -2.358 17.704 1.00 43.70 ? 309 TYR B CE1 1 ATOM 5581 C CE2 . TYR B 1 309 ? 20.566 -3.402 17.274 1.00 32.41 ? 309 TYR B CE2 1 ATOM 5582 C CZ . TYR B 1 309 ? 21.417 -2.322 17.146 1.00 38.57 ? 309 TYR B CZ 1 ATOM 5583 O OH . TYR B 1 309 ? 21.022 -1.194 16.457 1.00 50.64 ? 309 TYR B OH 1 ATOM 5584 N N . TYR B 1 310 ? 25.115 -8.587 18.685 1.00 31.59 ? 310 TYR B N 1 ATOM 5585 C CA . TYR B 1 310 ? 25.663 -9.803 19.274 1.00 30.44 ? 310 TYR B CA 1 ATOM 5586 C C . TYR B 1 310 ? 27.121 -10.048 18.913 1.00 39.10 ? 310 TYR B C 1 ATOM 5587 O O . TYR B 1 310 ? 27.853 -10.596 19.745 1.00 35.59 ? 310 TYR B O 1 ATOM 5588 C CB . TYR B 1 310 ? 24.798 -10.986 18.805 1.00 33.40 ? 310 TYR B CB 1 ATOM 5589 C CG . TYR B 1 310 ? 25.265 -12.402 19.086 1.00 36.27 ? 310 TYR B CG 1 ATOM 5590 C CD1 . TYR B 1 310 ? 24.836 -13.087 20.218 1.00 26.74 ? 310 TYR B CD1 1 ATOM 5591 C CD2 . TYR B 1 310 ? 26.073 -13.081 18.173 1.00 33.66 ? 310 TYR B CD2 1 ATOM 5592 C CE1 . TYR B 1 310 ? 25.231 -14.407 20.451 1.00 33.28 ? 310 TYR B CE1 1 ATOM 5593 C CE2 . TYR B 1 310 ? 26.479 -14.378 18.394 1.00 32.93 ? 310 TYR B CE2 1 ATOM 5594 C CZ . TYR B 1 310 ? 26.058 -15.044 19.532 1.00 33.73 ? 310 TYR B CZ 1 ATOM 5595 O OH . TYR B 1 310 ? 26.456 -16.349 19.742 1.00 33.94 ? 310 TYR B OH 1 ATOM 5596 N N . LYS B 1 311 ? 27.584 -9.609 17.737 1.00 35.64 ? 311 LYS B N 1 ATOM 5597 C CA . LYS B 1 311 ? 28.893 -10.011 17.229 1.00 35.34 ? 311 LYS B CA 1 ATOM 5598 C C . LYS B 1 311 ? 30.043 -9.476 18.076 1.00 31.52 ? 311 LYS B C 1 ATOM 5599 O O . LYS B 1 311 ? 31.120 -10.080 18.094 1.00 38.27 ? 311 LYS B O 1 ATOM 5600 C CB . LYS B 1 311 ? 29.055 -9.542 15.778 1.00 36.05 ? 311 LYS B CB 1 ATOM 5601 C CG . LYS B 1 311 ? 29.165 -8.027 15.640 1.00 34.27 ? 311 LYS B CG 1 ATOM 5602 C CD . LYS B 1 311 ? 29.673 -7.617 14.265 1.00 45.61 ? 311 LYS B CD 1 ATOM 5603 C CE . LYS B 1 311 ? 28.566 -7.672 13.247 1.00 51.53 ? 311 LYS B CE 1 ATOM 5604 N NZ . LYS B 1 311 ? 29.036 -7.881 11.838 1.00 39.12 ? 311 LYS B NZ 1 ATOM 5605 N N . LYS B 1 312 ? 29.859 -8.355 18.767 1.00 31.50 ? 312 LYS B N 1 ATOM 5606 C CA . LYS B 1 312 ? 30.961 -7.787 19.538 1.00 33.70 ? 312 LYS B CA 1 ATOM 5607 C C . LYS B 1 312 ? 31.132 -8.437 20.911 1.00 37.99 ? 312 LYS B C 1 ATOM 5608 O O . LYS B 1 312 ? 31.949 -7.955 21.705 1.00 36.87 ? 312 LYS B O 1 ATOM 5609 C CB . LYS B 1 312 ? 30.772 -6.278 19.705 1.00 31.69 ? 312 LYS B CB 1 ATOM 5610 C CG . LYS B 1 312 ? 30.744 -5.521 18.390 1.00 39.37 ? 312 LYS B CG 1 ATOM 5611 C CD . LYS B 1 312 ? 30.246 -4.093 18.552 1.00 38.58 ? 312 LYS B CD 1 ATOM 5612 C CE . LYS B 1 312 ? 31.138 -3.289 19.469 1.00 44.13 ? 312 LYS B CE 1 ATOM 5613 N NZ . LYS B 1 312 ? 30.824 -1.833 19.430 1.00 47.72 ? 312 LYS B NZ 1 ATOM 5614 N N . GLY B 1 313 ? 30.399 -9.511 21.203 1.00 35.42 ? 313 GLY B N 1 ATOM 5615 C CA . GLY B 1 313 ? 30.532 -10.179 22.492 1.00 30.93 ? 313 GLY B CA 1 ATOM 5616 C C . GLY B 1 313 ? 31.870 -10.899 22.595 1.00 35.18 ? 313 GLY B C 1 ATOM 5617 O O . GLY B 1 313 ? 32.278 -11.614 21.673 1.00 36.91 ? 313 GLY B O 1 ATOM 5618 N N . LYS B 1 314 ? 32.549 -10.723 23.730 1.00 42.22 ? 314 LYS B N 1 ATOM 5619 C CA . LYS B 1 314 ? 33.873 -11.320 23.888 1.00 36.73 ? 314 LYS B CA 1 ATOM 5620 C C . LYS B 1 314 ? 33.844 -12.845 23.937 1.00 41.44 ? 314 LYS B C 1 ATOM 5621 O O . LYS B 1 314 ? 34.879 -13.474 23.683 1.00 37.55 ? 314 LYS B O 1 ATOM 5622 C CB . LYS B 1 314 ? 34.559 -10.762 25.136 1.00 39.44 ? 314 LYS B CB 1 ATOM 5623 C CG . LYS B 1 314 ? 33.953 -11.211 26.455 1.00 45.14 ? 314 LYS B CG 1 ATOM 5624 C CD . LYS B 1 314 ? 34.737 -10.643 27.632 1.00 43.47 ? 314 LYS B CD 1 ATOM 5625 C CE . LYS B 1 314 ? 33.962 -10.792 28.939 1.00 47.10 ? 314 LYS B CE 1 ATOM 5626 N NZ . LYS B 1 314 ? 34.786 -10.459 30.142 1.00 51.11 ? 314 LYS B NZ 1 ATOM 5627 N N . PHE B 1 315 ? 32.705 -13.464 24.243 1.00 34.79 ? 315 PHE B N 1 ATOM 5628 C CA . PHE B 1 315 ? 32.629 -14.920 24.260 1.00 31.00 ? 315 PHE B CA 1 ATOM 5629 C C . PHE B 1 315 ? 32.047 -15.523 22.982 1.00 31.67 ? 315 PHE B C 1 ATOM 5630 O O . PHE B 1 315 ? 31.940 -16.750 22.893 1.00 34.57 ? 315 PHE B O 1 ATOM 5631 C CB . PHE B 1 315 ? 31.820 -15.405 25.474 1.00 35.20 ? 315 PHE B CB 1 ATOM 5632 C CG . PHE B 1 315 ? 32.412 -15.009 26.801 1.00 37.44 ? 315 PHE B CG 1 ATOM 5633 C CD1 . PHE B 1 315 ? 33.685 -15.433 27.164 1.00 39.75 ? 315 PHE B CD1 1 ATOM 5634 C CD2 . PHE B 1 315 ? 31.693 -14.230 27.694 1.00 35.25 ? 315 PHE B CD2 1 ATOM 5635 C CE1 . PHE B 1 315 ? 34.234 -15.069 28.389 1.00 41.08 ? 315 PHE B CE1 1 ATOM 5636 C CE2 . PHE B 1 315 ? 32.235 -13.865 28.921 1.00 39.68 ? 315 PHE B CE2 1 ATOM 5637 C CZ . PHE B 1 315 ? 33.507 -14.286 29.269 1.00 40.12 ? 315 PHE B CZ 1 ATOM 5638 N N . VAL B 1 316 ? 31.672 -14.707 21.991 1.00 39.21 ? 316 VAL B N 1 ATOM 5639 C CA . VAL B 1 316 ? 31.104 -15.248 20.756 1.00 33.19 ? 316 VAL B CA 1 ATOM 5640 C C . VAL B 1 316 ? 32.139 -16.113 20.043 1.00 34.31 ? 316 VAL B C 1 ATOM 5641 O O . VAL B 1 316 ? 33.310 -15.735 19.916 1.00 39.12 ? 316 VAL B O 1 ATOM 5642 C CB . VAL B 1 316 ? 30.607 -14.109 19.847 1.00 35.79 ? 316 VAL B CB 1 ATOM 5643 C CG1 . VAL B 1 316 ? 30.092 -14.664 18.514 1.00 34.10 ? 316 VAL B CG1 1 ATOM 5644 C CG2 . VAL B 1 316 ? 29.515 -13.312 20.545 1.00 30.77 ? 316 VAL B CG2 1 ATOM 5645 N N . SER B 1 317 ? 31.704 -17.285 19.570 1.00 33.79 ? 317 SER B N 1 ATOM 5646 C CA . SER B 1 317 ? 32.569 -18.266 18.931 1.00 36.58 ? 317 SER B CA 1 ATOM 5647 C C . SER B 1 317 ? 32.966 -17.838 17.520 1.00 47.69 ? 317 SER B C 1 ATOM 5648 O O . SER B 1 317 ? 32.299 -17.001 16.900 1.00 42.86 ? 317 SER B O 1 ATOM 5649 C CB . SER B 1 317 ? 31.862 -19.617 18.875 1.00 45.65 ? 317 SER B CB 1 ATOM 5650 O OG . SER B 1 317 ? 30.659 -19.525 18.134 1.00 45.35 ? 317 SER B OG 1 ATOM 5651 N N . PRO B 1 318 ? 34.053 -18.411 16.983 1.00 43.17 ? 318 PRO B N 1 ATOM 5652 C CA . PRO B 1 318 ? 34.479 -18.040 15.622 1.00 49.44 ? 318 PRO B CA 1 ATOM 5653 C C . PRO B 1 318 ? 33.442 -18.352 14.559 1.00 41.86 ? 318 PRO B C 1 ATOM 5654 O O . PRO B 1 318 ? 33.290 -17.576 13.610 1.00 46.09 ? 318 PRO B O 1 ATOM 5655 C CB . PRO B 1 318 ? 35.762 -18.862 15.421 1.00 49.98 ? 318 PRO B CB 1 ATOM 5656 C CG . PRO B 1 318 ? 36.235 -19.192 16.811 1.00 49.85 ? 318 PRO B CG 1 ATOM 5657 C CD . PRO B 1 318 ? 34.987 -19.363 17.613 1.00 42.93 ? 318 PRO B CD 1 ATOM 5658 N N . LEU B 1 319 ? 32.730 -19.469 14.681 1.00 46.51 ? 319 LEU B N 1 ATOM 5659 C CA . LEU B 1 319 ? 31.621 -19.794 13.797 1.00 44.83 ? 319 LEU B CA 1 ATOM 5660 C C . LEU B 1 319 ? 30.365 -19.964 14.636 1.00 48.05 ? 319 LEU B C 1 ATOM 5661 O O . LEU B 1 319 ? 30.395 -20.630 15.676 1.00 39.97 ? 319 LEU B O 1 ATOM 5662 C CB . LEU B 1 319 ? 31.889 -21.070 12.992 1.00 48.74 ? 319 LEU B CB 1 ATOM 5663 C CG . LEU B 1 319 ? 33.137 -21.108 12.104 1.00 47.98 ? 319 LEU B CG 1 ATOM 5664 C CD1 . LEU B 1 319 ? 33.092 -22.337 11.212 1.00 44.66 ? 319 LEU B CD1 1 ATOM 5665 C CD2 . LEU B 1 319 ? 33.292 -19.828 11.279 1.00 53.15 ? 319 LEU B CD2 1 ATOM 5666 N N . THR B 1 320 ? 29.266 -19.368 14.184 1.00 43.36 ? 320 THR B N 1 ATOM 5667 C CA . THR B 1 320 ? 27.991 -19.474 14.879 1.00 43.73 ? 320 THR B CA 1 ATOM 5668 C C . THR B 1 320 ? 26.927 -19.909 13.887 1.00 36.09 ? 320 THR B C 1 ATOM 5669 O O . THR B 1 320 ? 26.760 -19.285 12.836 1.00 40.20 ? 320 THR B O 1 ATOM 5670 C CB . THR B 1 320 ? 27.596 -18.146 15.534 1.00 43.80 ? 320 THR B CB 1 ATOM 5671 O OG1 . THR B 1 320 ? 28.676 -17.682 16.355 1.00 40.31 ? 320 THR B OG1 1 ATOM 5672 C CG2 . THR B 1 320 ? 26.356 -18.329 16.389 1.00 35.96 ? 320 THR B CG2 1 ATOM 5673 N N . LEU B 1 321 ? 26.225 -20.983 14.220 1.00 35.67 ? 321 LEU B N 1 ATOM 5674 C CA . LEU B 1 321 ? 25.155 -21.513 13.392 1.00 38.27 ? 321 LEU B CA 1 ATOM 5675 C C . LEU B 1 321 ? 23.817 -20.973 13.880 1.00 42.59 ? 321 LEU B C 1 ATOM 5676 O O . LEU B 1 321 ? 23.593 -20.846 15.087 1.00 39.18 ? 321 LEU B O 1 ATOM 5677 C CB . LEU B 1 321 ? 25.142 -23.039 13.437 1.00 40.08 ? 321 LEU B CB 1 ATOM 5678 C CG . LEU B 1 321 ? 26.505 -23.730 13.457 1.00 43.32 ? 321 LEU B CG 1 ATOM 5679 C CD1 . LEU B 1 321 ? 26.326 -25.244 13.437 1.00 43.99 ? 321 LEU B CD1 1 ATOM 5680 C CD2 . LEU B 1 321 ? 27.378 -23.261 12.299 1.00 48.36 ? 321 LEU B CD2 1 ATOM 5681 N N . VAL B 1 322 ? 22.933 -20.648 12.939 1.00 33.35 ? 322 VAL B N 1 ATOM 5682 C CA . VAL B 1 322 ? 21.601 -20.128 13.243 1.00 33.91 ? 322 VAL B CA 1 ATOM 5683 C C . VAL B 1 322 ? 20.598 -20.874 12.374 1.00 37.20 ? 322 VAL B C 1 ATOM 5684 O O . VAL B 1 322 ? 20.579 -20.698 11.150 1.00 40.96 ? 322 VAL B O 1 ATOM 5685 C CB . VAL B 1 322 ? 21.499 -18.617 13.011 1.00 36.39 ? 322 VAL B CB 1 ATOM 5686 C CG1 . VAL B 1 322 ? 20.103 -18.117 13.402 1.00 33.51 ? 322 VAL B CG1 1 ATOM 5687 C CG2 . VAL B 1 322 ? 22.561 -17.895 13.797 1.00 32.17 ? 322 VAL B CG2 1 ATOM 5688 N N . ALA B 1 323 ? 19.775 -21.710 12.996 1.00 34.27 ? 323 ALA B N 1 ATOM 5689 C CA . ALA B 1 323 ? 18.819 -22.503 12.249 1.00 33.26 ? 323 ALA B CA 1 ATOM 5690 C C . ALA B 1 323 ? 17.626 -21.653 11.818 1.00 40.40 ? 323 ALA B C 1 ATOM 5691 O O . ALA B 1 323 ? 17.281 -20.646 12.446 1.00 36.78 ? 323 ALA B O 1 ATOM 5692 C CB . ALA B 1 323 ? 18.333 -23.689 13.081 1.00 35.00 ? 323 ALA B CB 1 ATOM 5693 N N . ASP B 1 324 ? 17.005 -22.067 10.716 1.00 38.26 ? 324 ASP B N 1 ATOM 5694 C CA . ASP B 1 324 ? 15.724 -21.503 10.319 1.00 38.44 ? 324 ASP B CA 1 ATOM 5695 C C . ASP B 1 324 ? 14.639 -21.924 11.303 1.00 36.87 ? 324 ASP B C 1 ATOM 5696 O O . ASP B 1 324 ? 14.742 -22.958 11.972 1.00 34.90 ? 324 ASP B O 1 ATOM 5697 C CB . ASP B 1 324 ? 15.343 -21.957 8.909 1.00 41.26 ? 324 ASP B CB 1 ATOM 5698 C CG . ASP B 1 324 ? 16.216 -21.333 7.825 1.00 50.07 ? 324 ASP B CG 1 ATOM 5699 O OD1 . ASP B 1 324 ? 16.967 -20.370 8.113 1.00 49.87 ? 324 ASP B OD1 1 ATOM 5700 O OD2 . ASP B 1 324 ? 16.131 -21.804 6.669 1.00 49.82 ? 324 ASP B OD2 1 ATOM 5701 N N . GLU B 1 325 ? 13.587 -21.111 11.380 1.00 32.51 ? 325 GLU B N 1 ATOM 5702 C CA . GLU B 1 325 ? 12.530 -21.342 12.356 1.00 33.25 ? 325 GLU B CA 1 ATOM 5703 C C . GLU B 1 325 ? 11.933 -22.732 12.185 1.00 37.12 ? 325 GLU B C 1 ATOM 5704 O O . GLU B 1 325 ? 11.529 -23.116 11.084 1.00 38.39 ? 325 GLU B O 1 ATOM 5705 C CB . GLU B 1 325 ? 11.435 -20.283 12.213 1.00 38.06 ? 325 GLU B CB 1 ATOM 5706 C CG . GLU B 1 325 ? 10.357 -20.376 13.288 1.00 37.20 ? 325 GLU B CG 1 ATOM 5707 C CD . GLU B 1 325 ? 9.220 -19.399 13.060 1.00 42.02 ? 325 GLU B CD 1 ATOM 5708 O OE1 . GLU B 1 325 ? 8.548 -19.510 12.015 1.00 46.57 ? 325 GLU B OE1 1 ATOM 5709 O OE2 . GLU B 1 325 ? 9.007 -18.511 13.918 1.00 41.93 ? 325 GLU B OE2 1 ATOM 5710 N N . GLY B 1 326 ? 11.871 -23.481 13.283 1.00 34.41 ? 326 GLY B N 1 ATOM 5711 C CA . GLY B 1 326 ? 11.349 -24.828 13.285 1.00 34.65 ? 326 GLY B CA 1 ATOM 5712 C C . GLY B 1 326 ? 12.403 -25.913 13.184 1.00 31.85 ? 326 GLY B C 1 ATOM 5713 O O . GLY B 1 326 ? 12.101 -27.076 13.478 1.00 35.56 ? 326 GLY B O 1 ATOM 5714 N N . TRP B 1 327 ? 13.626 -25.560 12.794 1.00 31.05 ? 327 TRP B N 1 ATOM 5715 C CA . TRP B 1 327 ? 14.723 -26.500 12.623 1.00 40.95 ? 327 TRP B CA 1 ATOM 5716 C C . TRP B 1 327 ? 15.602 -26.531 13.871 1.00 46.91 ? 327 TRP B C 1 ATOM 5717 O O . TRP B 1 327 ? 15.636 -25.586 14.664 1.00 39.83 ? 327 TRP B O 1 ATOM 5718 C CB . TRP B 1 327 ? 15.555 -26.140 11.384 1.00 38.07 ? 327 TRP B CB 1 ATOM 5719 C CG . TRP B 1 327 ? 14.814 -26.390 10.102 1.00 48.83 ? 327 TRP B CG 1 ATOM 5720 C CD1 . TRP B 1 327 ? 13.829 -25.613 9.558 1.00 47.80 ? 327 TRP B CD1 1 ATOM 5721 C CD2 . TRP B 1 327 ? 14.978 -27.505 9.216 1.00 50.94 ? 327 TRP B CD2 1 ATOM 5722 N NE1 . TRP B 1 327 ? 13.374 -26.173 8.387 1.00 49.69 ? 327 TRP B NE1 1 ATOM 5723 C CE2 . TRP B 1 327 ? 14.065 -27.333 8.154 1.00 54.39 ? 327 TRP B CE2 1 ATOM 5724 C CE3 . TRP B 1 327 ? 15.814 -28.626 9.212 1.00 50.32 ? 327 TRP B CE3 1 ATOM 5725 C CZ2 . TRP B 1 327 ? 13.963 -28.243 7.102 1.00 57.34 ? 327 TRP B CZ2 1 ATOM 5726 C CZ3 . TRP B 1 327 ? 15.711 -29.529 8.167 1.00 50.41 ? 327 TRP B CZ3 1 ATOM 5727 C CH2 . TRP B 1 327 ? 14.792 -29.333 7.128 1.00 50.54 ? 327 TRP B CH2 1 ATOM 5728 N N . PHE B 1 328 ? 16.320 -27.641 14.035 1.00 42.83 ? 328 PHE B N 1 ATOM 5729 C CA . PHE B 1 328 ? 17.053 -27.919 15.267 1.00 44.05 ? 328 PHE B CA 1 ATOM 5730 C C . PHE B 1 328 ? 18.425 -28.473 14.910 1.00 45.34 ? 328 PHE B C 1 ATOM 5731 O O . PHE B 1 328 ? 18.517 -29.484 14.207 1.00 43.21 ? 328 PHE B O 1 ATOM 5732 C CB . PHE B 1 328 ? 16.272 -28.912 16.138 1.00 42.81 ? 328 PHE B CB 1 ATOM 5733 C CG . PHE B 1 328 ? 16.690 -28.928 17.583 1.00 45.69 ? 328 PHE B CG 1 ATOM 5734 C CD1 . PHE B 1 328 ? 17.840 -29.590 17.980 1.00 44.61 ? 328 PHE B CD1 1 ATOM 5735 C CD2 . PHE B 1 328 ? 15.922 -28.296 18.551 1.00 45.01 ? 328 PHE B CD2 1 ATOM 5736 C CE1 . PHE B 1 328 ? 18.225 -29.615 19.311 1.00 46.06 ? 328 PHE B CE1 1 ATOM 5737 C CE2 . PHE B 1 328 ? 16.302 -28.323 19.887 1.00 37.92 ? 328 PHE B CE2 1 ATOM 5738 C CZ . PHE B 1 328 ? 17.452 -28.986 20.263 1.00 40.90 ? 328 PHE B CZ 1 ATOM 5739 N N . ILE B 1 329 ? 19.483 -27.828 15.401 1.00 41.51 ? 329 ILE B N 1 ATOM 5740 C CA . ILE B 1 329 ? 20.858 -28.231 15.119 1.00 41.48 ? 329 ILE B CA 1 ATOM 5741 C C . ILE B 1 329 ? 21.401 -29.048 16.284 1.00 51.14 ? 329 ILE B C 1 ATOM 5742 O O . ILE B 1 329 ? 21.261 -28.656 17.450 1.00 48.26 ? 329 ILE B O 1 ATOM 5743 C CB . ILE B 1 329 ? 21.755 -27.011 14.865 1.00 44.32 ? 329 ILE B CB 1 ATOM 5744 C CG1 . ILE B 1 329 ? 21.257 -26.218 13.658 1.00 36.54 ? 329 ILE B CG1 1 ATOM 5745 C CG2 . ILE B 1 329 ? 23.209 -27.444 14.701 1.00 41.65 ? 329 ILE B CG2 1 ATOM 5746 C CD1 . ILE B 1 329 ? 22.032 -24.941 13.435 1.00 35.29 ? 329 ILE B CD1 1 ATOM 5747 N N . ALA B 1 330 ? 22.050 -30.168 15.970 1.00 46.36 ? 330 ALA B N 1 ATOM 5748 C CA . ALA B 1 330 ? 22.706 -30.981 16.980 1.00 46.87 ? 330 ALA B CA 1 ATOM 5749 C C . ALA B 1 330 ? 23.846 -31.745 16.324 1.00 61.26 ? 330 ALA B C 1 ATOM 5750 O O . ALA B 1 330 ? 24.000 -31.744 15.100 1.00 54.08 ? 330 ALA B O 1 ATOM 5751 C CB . ALA B 1 330 ? 21.723 -31.942 17.654 1.00 48.40 ? 330 ALA B CB 1 ATOM 5752 N N . GLU B 1 331 ? 24.659 -32.398 17.156 1.00 57.52 ? 331 GLU B N 1 ATOM 5753 C CA . GLU B 1 331 ? 25.710 -33.256 16.619 1.00 62.63 ? 331 GLU B CA 1 ATOM 5754 C C . GLU B 1 331 ? 25.107 -34.462 15.910 1.00 57.05 ? 331 GLU B C 1 ATOM 5755 O O . GLU B 1 331 ? 25.502 -34.798 14.789 1.00 58.02 ? 331 GLU B O 1 ATOM 5756 C CB . GLU B 1 331 ? 26.657 -33.706 17.736 1.00 65.34 ? 331 GLU B CB 1 ATOM 5757 C CG . GLU B 1 331 ? 27.289 -32.573 18.533 1.00 67.91 ? 331 GLU B CG 1 ATOM 5758 C CD . GLU B 1 331 ? 26.477 -32.184 19.766 1.00 72.82 ? 331 GLU B CD 1 ATOM 5759 O OE1 . GLU B 1 331 ? 25.233 -32.328 19.752 1.00 66.48 ? 331 GLU B OE1 1 ATOM 5760 O OE2 . GLU B 1 331 ? 27.092 -31.737 20.759 1.00 72.24 ? 331 GLU B OE2 1 ATOM 5761 N N . SER B 1 332 ? 24.132 -35.110 16.540 1.00 59.04 ? 332 SER B N 1 ATOM 5762 C CA . SER B 1 332 ? 23.529 -36.307 15.977 1.00 63.16 ? 332 SER B CA 1 ATOM 5763 C C . SER B 1 332 ? 22.164 -36.518 16.611 1.00 59.83 ? 332 SER B C 1 ATOM 5764 O O . SER B 1 332 ? 21.841 -35.925 17.642 1.00 61.07 ? 332 SER B O 1 ATOM 5765 C CB . SER B 1 332 ? 24.422 -37.531 16.195 1.00 68.61 ? 332 SER B CB 1 ATOM 5766 O OG . SER B 1 332 ? 24.780 -37.648 17.558 1.00 58.28 ? 332 SER B OG 1 ATOM 5767 N N . ARG B 1 333 ? 21.370 -37.383 15.974 1.00 58.92 ? 333 ARG B N 1 ATOM 5768 C CA . ARG B 1 333 ? 20.025 -37.667 16.466 1.00 63.93 ? 333 ARG B CA 1 ATOM 5769 C C . ARG B 1 333 ? 20.054 -38.175 17.906 1.00 65.78 ? 333 ARG B C 1 ATOM 5770 O O . ARG B 1 333 ? 19.187 -37.822 18.716 1.00 59.28 ? 333 ARG B O 1 ATOM 5771 C CB . ARG B 1 333 ? 19.331 -38.674 15.538 1.00 66.07 ? 333 ARG B CB 1 ATOM 5772 C CG . ARG B 1 333 ? 19.867 -40.112 15.615 1.00 73.73 ? 333 ARG B CG 1 ATOM 5773 C CD . ARG B 1 333 ? 20.077 -40.722 14.231 1.00 78.01 ? 333 ARG B CD 1 ATOM 5774 N NE . ARG B 1 333 ? 21.354 -40.323 13.640 1.00 76.25 ? 333 ARG B NE 1 ATOM 5775 C CZ . ARG B 1 333 ? 21.597 -40.288 12.332 1.00 70.27 ? 333 ARG B CZ 1 ATOM 5776 N NH1 . ARG B 1 333 ? 20.644 -40.609 11.467 1.00 71.85 ? 333 ARG B NH1 1 ATOM 5777 N NH2 . ARG B 1 333 ? 22.789 -39.907 11.891 1.00 64.40 ? 333 ARG B NH2 1 ATOM 5778 N N . GLU B 1 334 ? 21.061 -38.983 18.254 1.00 69.01 ? 334 GLU B N 1 ATOM 5779 C CA . GLU B 1 334 ? 21.170 -39.518 19.606 1.00 70.12 ? 334 GLU B CA 1 ATOM 5780 C C . GLU B 1 334 ? 21.673 -38.490 20.612 1.00 62.68 ? 334 GLU B C 1 ATOM 5781 O O . GLU B 1 334 ? 21.690 -38.779 21.813 1.00 64.00 ? 334 GLU B O 1 ATOM 5782 C CB . GLU B 1 334 ? 22.085 -40.747 19.616 1.00 65.44 ? 334 GLU B CB 1 ATOM 5783 N N . MET B 1 335 ? 22.074 -37.305 20.159 1.00 59.14 ? 335 MET B N 1 ATOM 5784 C CA . MET B 1 335 ? 22.495 -36.228 21.042 1.00 60.49 ? 335 MET B CA 1 ATOM 5785 C C . MET B 1 335 ? 21.417 -35.167 21.234 1.00 56.21 ? 335 MET B C 1 ATOM 5786 O O . MET B 1 335 ? 21.706 -34.102 21.786 1.00 54.96 ? 335 MET B O 1 ATOM 5787 C CB . MET B 1 335 ? 23.771 -35.576 20.510 1.00 59.86 ? 335 MET B CB 1 ATOM 5788 C CG . MET B 1 335 ? 24.947 -36.521 20.393 1.00 68.87 ? 335 MET B CG 1 ATOM 5789 S SD . MET B 1 335 ? 26.366 -35.985 21.357 1.00 75.35 ? 335 MET B SD 1 ATOM 5790 C CE . MET B 1 335 ? 25.922 -36.605 22.977 1.00 64.64 ? 335 MET B CE 1 ATOM 5791 N N . LEU B 1 336 ? 20.192 -35.423 20.785 1.00 53.91 ? 336 LEU B N 1 ATOM 5792 C CA . LEU B 1 336 ? 19.121 -34.460 20.975 1.00 46.52 ? 336 LEU B CA 1 ATOM 5793 C C . LEU B 1 336 ? 18.711 -34.418 22.448 1.00 45.97 ? 336 LEU B C 1 ATOM 5794 O O . LEU B 1 336 ? 18.914 -35.384 23.182 1.00 43.36 ? 336 LEU B O 1 ATOM 5795 C CB . LEU B 1 336 ? 17.923 -34.816 20.100 1.00 53.09 ? 336 LEU B CB 1 ATOM 5796 C CG . LEU B 1 336 ? 18.095 -34.585 18.593 1.00 53.52 ? 336 LEU B CG 1 ATOM 5797 C CD1 . LEU B 1 336 ? 16.916 -35.151 17.835 1.00 50.24 ? 336 LEU B CD1 1 ATOM 5798 C CD2 . LEU B 1 336 ? 18.259 -33.101 18.278 1.00 46.98 ? 336 LEU B CD2 1 ATOM 5799 N N . PRO B 1 337 ? 18.131 -33.263 22.927 1.00 47.95 ? 337 PRO B N 1 ATOM 5800 C CA . PRO B 1 337 ? 17.795 -33.147 24.365 1.00 41.80 ? 337 PRO B CA 1 ATOM 5801 C C . PRO B 1 337 ? 16.452 -33.773 24.722 1.00 42.30 ? 337 PRO B C 1 ATOM 5802 O O . PRO B 1 337 ? 15.489 -33.099 25.113 1.00 36.84 ? 337 PRO B O 1 ATOM 5803 C CB . PRO B 1 337 ? 17.808 -31.631 24.577 1.00 43.86 ? 337 PRO B CB 1 ATOM 5804 C CG . PRO B 1 337 ? 17.337 -31.091 23.276 1.00 40.32 ? 337 PRO B CG 1 ATOM 5805 C CD . PRO B 1 337 ? 17.942 -31.986 22.217 1.00 45.54 ? 337 PRO B CD 1 ATOM 5806 N N . PHE B 1 338 ? 16.377 -35.098 24.604 1.00 43.40 ? 338 PHE B N 1 ATOM 5807 C CA . PHE B 1 338 ? 15.163 -35.815 24.973 1.00 41.52 ? 338 PHE B CA 1 ATOM 5808 C C . PHE B 1 338 ? 14.826 -35.567 26.438 1.00 40.71 ? 338 PHE B C 1 ATOM 5809 O O . PHE B 1 338 ? 15.709 -35.387 27.279 1.00 39.23 ? 338 PHE B O 1 ATOM 5810 C CB . PHE B 1 338 ? 15.329 -37.320 24.730 1.00 44.94 ? 338 PHE B CB 1 ATOM 5811 C CG . PHE B 1 338 ? 15.704 -37.677 23.315 1.00 50.14 ? 338 PHE B CG 1 ATOM 5812 C CD1 . PHE B 1 338 ? 17.038 -37.745 22.933 1.00 51.41 ? 338 PHE B CD1 1 ATOM 5813 C CD2 . PHE B 1 338 ? 14.729 -37.958 22.371 1.00 50.99 ? 338 PHE B CD2 1 ATOM 5814 C CE1 . PHE B 1 338 ? 17.395 -38.076 21.633 1.00 51.00 ? 338 PHE B CE1 1 ATOM 5815 C CE2 . PHE B 1 338 ? 15.080 -38.290 21.066 1.00 54.58 ? 338 PHE B CE2 1 ATOM 5816 C CZ . PHE B 1 338 ? 16.417 -38.347 20.699 1.00 49.74 ? 338 PHE B CZ 1 ATOM 5817 N N . TRP B 1 339 ? 13.535 -35.571 26.750 1.00 39.17 ? 339 TRP B N 1 ATOM 5818 C CA . TRP B 1 339 ? 13.090 -35.262 28.099 1.00 48.01 ? 339 TRP B CA 1 ATOM 5819 C C . TRP B 1 339 ? 12.437 -36.473 28.746 1.00 50.10 ? 339 TRP B C 1 ATOM 5820 O O . TRP B 1 339 ? 11.958 -37.390 28.077 1.00 47.47 ? 339 TRP B O 1 ATOM 5821 C CB . TRP B 1 339 ? 12.126 -34.065 28.129 1.00 40.97 ? 339 TRP B CB 1 ATOM 5822 C CG . TRP B 1 339 ? 10.852 -34.207 27.344 1.00 36.86 ? 339 TRP B CG 1 ATOM 5823 C CD1 . TRP B 1 339 ? 10.706 -34.096 25.992 1.00 34.07 ? 339 TRP B CD1 1 ATOM 5824 C CD2 . TRP B 1 339 ? 9.536 -34.428 27.870 1.00 36.49 ? 339 TRP B CD2 1 ATOM 5825 N NE1 . TRP B 1 339 ? 9.389 -34.254 25.644 1.00 37.62 ? 339 TRP B NE1 1 ATOM 5826 C CE2 . TRP B 1 339 ? 8.649 -34.459 26.777 1.00 36.01 ? 339 TRP B CE2 1 ATOM 5827 C CE3 . TRP B 1 339 ? 9.025 -34.607 29.157 1.00 41.32 ? 339 TRP B CE3 1 ATOM 5828 C CZ2 . TRP B 1 339 ? 7.276 -34.665 26.931 1.00 44.52 ? 339 TRP B CZ2 1 ATOM 5829 C CZ3 . TRP B 1 339 ? 7.663 -34.807 29.311 1.00 44.84 ? 339 TRP B CZ3 1 ATOM 5830 C CH2 . TRP B 1 339 ? 6.803 -34.834 28.203 1.00 41.99 ? 339 TRP B CH2 1 ATOM 5831 N N . MET B 1 340 ? 12.414 -36.446 30.076 1.00 53.69 ? 340 MET B N 1 ATOM 5832 C CA . MET B 1 340 ? 11.984 -37.589 30.877 1.00 58.87 ? 340 MET B CA 1 ATOM 5833 C C . MET B 1 340 ? 10.460 -37.608 30.938 1.00 55.62 ? 340 MET B C 1 ATOM 5834 O O . MET B 1 340 ? 9.830 -37.202 31.918 1.00 56.10 ? 340 MET B O 1 ATOM 5835 C CB . MET B 1 340 ? 12.614 -37.522 32.261 1.00 64.05 ? 340 MET B CB 1 ATOM 5836 C CG . MET B 1 340 ? 12.383 -38.750 33.109 1.00 69.73 ? 340 MET B CG 1 ATOM 5837 S SD . MET B 1 340 ? 13.642 -38.869 34.380 1.00 76.10 ? 340 MET B SD 1 ATOM 5838 C CE . MET B 1 340 ? 15.113 -39.003 33.366 1.00 68.68 ? 340 MET B CE 1 ATOM 5839 N N . ASN B 1 341 ? 9.859 -38.097 29.854 1.00 52.76 ? 341 ASN B N 1 ATOM 5840 C CA . ASN B 1 341 ? 8.414 -38.272 29.802 1.00 57.85 ? 341 ASN B CA 1 ATOM 5841 C C . ASN B 1 341 ? 7.964 -39.582 30.429 1.00 67.55 ? 341 ASN B C 1 ATOM 5842 O O . ASN B 1 341 ? 6.802 -39.695 30.836 1.00 67.65 ? 341 ASN B O 1 ATOM 5843 C CB . ASN B 1 341 ? 7.928 -38.218 28.357 1.00 61.05 ? 341 ASN B CB 1 ATOM 5844 C CG . ASN B 1 341 ? 8.394 -39.406 27.545 1.00 61.50 ? 341 ASN B CG 1 ATOM 5845 O OD1 . ASN B 1 341 ? 9.549 -39.821 27.628 1.00 63.53 ? 341 ASN B OD1 1 ATOM 5846 N ND2 . ASN B 1 341 ? 7.491 -39.962 26.756 1.00 66.44 ? 341 ASN B ND2 1 ATOM 5847 N N . SER B 1 342 ? 8.850 -40.569 30.507 1.00 69.28 ? 342 SER B N 1 ATOM 5848 C CA . SER B 1 342 ? 8.560 -41.827 31.169 1.00 77.46 ? 342 SER B CA 1 ATOM 5849 C C . SER B 1 342 ? 9.669 -42.121 32.169 1.00 78.95 ? 342 SER B C 1 ATOM 5850 O O . SER B 1 342 ? 10.760 -41.549 32.105 1.00 78.81 ? 342 SER B O 1 ATOM 5851 C CB . SER B 1 342 ? 8.417 -42.978 30.166 1.00 80.65 ? 342 SER B CB 1 ATOM 5852 O OG . SER B 1 342 ? 7.578 -43.996 30.688 1.00 84.01 ? 342 SER B OG 1 ATOM 5853 N N . THR B 1 343 ? 9.376 -43.040 33.090 1.00 86.90 ? 343 THR B N 1 ATOM 5854 C CA . THR B 1 343 ? 10.239 -43.232 34.251 1.00 85.88 ? 343 THR B CA 1 ATOM 5855 C C . THR B 1 343 ? 11.603 -43.803 33.874 1.00 81.52 ? 343 THR B C 1 ATOM 5856 O O . THR B 1 343 ? 12.604 -43.483 34.525 1.00 83.48 ? 343 THR B O 1 ATOM 5857 C CB . THR B 1 343 ? 9.540 -44.133 35.274 1.00 89.46 ? 343 THR B CB 1 ATOM 5858 O OG1 . THR B 1 343 ? 10.356 -44.263 36.445 1.00 89.81 ? 343 THR B OG1 1 ATOM 5859 C CG2 . THR B 1 343 ? 9.259 -45.518 34.687 1.00 82.86 ? 343 THR B CG2 1 ATOM 5860 N N . GLY B 1 344 ? 11.672 -44.623 32.827 1.00 78.46 ? 344 GLY B N 1 ATOM 5861 C CA . GLY B 1 344 ? 12.897 -45.324 32.489 1.00 86.79 ? 344 GLY B CA 1 ATOM 5862 C C . GLY B 1 344 ? 14.078 -44.441 32.133 1.00 85.45 ? 344 GLY B C 1 ATOM 5863 O O . GLY B 1 344 ? 14.952 -44.189 32.968 1.00 84.70 ? 344 GLY B O 1 ATOM 5864 N N . LYS B 1 345 ? 14.124 -43.983 30.885 1.00 79.55 ? 345 LYS B N 1 ATOM 5865 C CA . LYS B 1 345 ? 15.183 -43.101 30.419 1.00 71.98 ? 345 LYS B CA 1 ATOM 5866 C C . LYS B 1 345 ? 14.574 -42.043 29.511 1.00 74.63 ? 345 LYS B C 1 ATOM 5867 O O . LYS B 1 345 ? 13.413 -42.138 29.101 1.00 78.40 ? 345 LYS B O 1 ATOM 5868 C CB . LYS B 1 345 ? 16.287 -43.875 29.687 1.00 61.61 ? 345 LYS B CB 1 ATOM 5869 N N . ARG B 1 346 ? 15.378 -41.030 29.193 1.00 68.88 ? 346 ARG B N 1 ATOM 5870 C CA . ARG B 1 346 ? 14.919 -39.871 28.430 1.00 57.34 ? 346 ARG B CA 1 ATOM 5871 C C . ARG B 1 346 ? 14.647 -40.272 26.987 1.00 51.67 ? 346 ARG B C 1 ATOM 5872 O O . ARG B 1 346 ? 15.565 -40.362 26.172 1.00 54.47 ? 346 ARG B O 1 ATOM 5873 C CB . ARG B 1 346 ? 15.959 -38.759 28.484 1.00 59.26 ? 346 ARG B CB 1 ATOM 5874 C CG . ARG B 1 346 ? 16.349 -38.322 29.879 1.00 63.87 ? 346 ARG B CG 1 ATOM 5875 C CD . ARG B 1 346 ? 17.382 -37.210 29.820 1.00 57.62 ? 346 ARG B CD 1 ATOM 5876 N NE . ARG B 1 346 ? 17.775 -36.760 31.148 1.00 70.02 ? 346 ARG B NE 1 ATOM 5877 C CZ . ARG B 1 346 ? 17.075 -35.902 31.884 1.00 77.51 ? 346 ARG B CZ 1 ATOM 5878 N NH1 . ARG B 1 346 ? 17.509 -35.547 33.085 1.00 84.64 ? 346 ARG B NH1 1 ATOM 5879 N NH2 . ARG B 1 346 ? 15.938 -35.400 31.421 1.00 76.56 ? 346 ARG B NH2 1 ATOM 5880 N N . GLU B 1 347 ? 13.375 -40.494 26.658 1.00 52.23 ? 347 GLU B N 1 ATOM 5881 C CA . GLU B 1 347 ? 12.956 -40.726 25.285 1.00 56.18 ? 347 GLU B CA 1 ATOM 5882 C C . GLU B 1 347 ? 11.990 -39.670 24.767 1.00 56.72 ? 347 GLU B C 1 ATOM 5883 O O . GLU B 1 347 ? 11.600 -39.736 23.596 1.00 57.05 ? 347 GLU B O 1 ATOM 5884 C CB . GLU B 1 347 ? 12.300 -42.111 25.152 1.00 63.41 ? 347 GLU B CB 1 ATOM 5885 C CG . GLU B 1 347 ? 11.175 -42.350 26.152 1.00 72.05 ? 347 GLU B CG 1 ATOM 5886 C CD . GLU B 1 347 ? 10.385 -43.619 25.868 1.00 75.02 ? 347 GLU B CD 1 ATOM 5887 O OE1 . GLU B 1 347 ? 10.711 -44.319 24.884 1.00 71.33 ? 347 GLU B OE1 1 ATOM 5888 O OE2 . GLU B 1 347 ? 9.435 -43.913 26.629 1.00 74.61 ? 347 GLU B OE2 1 ATOM 5889 N N . GLY B 1 348 ? 11.605 -38.701 25.595 1.00 49.35 ? 348 GLY B N 1 ATOM 5890 C CA . GLY B 1 348 ? 10.584 -37.753 25.187 1.00 52.55 ? 348 GLY B CA 1 ATOM 5891 C C . GLY B 1 348 ? 11.079 -36.823 24.093 1.00 42.50 ? 348 GLY B C 1 ATOM 5892 O O . GLY B 1 348 ? 12.202 -36.322 24.135 1.00 41.52 ? 348 GLY B O 1 ATOM 5893 N N . TRP B 1 349 ? 10.220 -36.583 23.109 1.00 48.24 ? 349 TRP B N 1 ATOM 5894 C CA . TRP B 1 349 ? 10.535 -35.669 22.021 1.00 47.24 ? 349 TRP B CA 1 ATOM 5895 C C . TRP B 1 349 ? 10.095 -34.256 22.384 1.00 44.10 ? 349 TRP B C 1 ATOM 5896 O O . TRP B 1 349 ? 8.981 -34.056 22.881 1.00 39.81 ? 349 TRP B O 1 ATOM 5897 C CB . TRP B 1 349 ? 9.850 -36.111 20.729 1.00 46.48 ? 349 TRP B CB 1 ATOM 5898 C CG . TRP B 1 349 ? 10.454 -37.324 20.098 1.00 56.78 ? 349 TRP B CG 1 ATOM 5899 C CD1 . TRP B 1 349 ? 11.272 -38.240 20.691 1.00 57.05 ? 349 TRP B CD1 1 ATOM 5900 C CD2 . TRP B 1 349 ? 10.295 -37.746 18.739 1.00 60.44 ? 349 TRP B CD2 1 ATOM 5901 N NE1 . TRP B 1 349 ? 11.627 -39.213 19.785 1.00 62.88 ? 349 TRP B NE1 1 ATOM 5902 C CE2 . TRP B 1 349 ? 11.040 -38.931 18.579 1.00 62.28 ? 349 TRP B CE2 1 ATOM 5903 C CE3 . TRP B 1 349 ? 9.591 -37.239 17.644 1.00 60.68 ? 349 TRP B CE3 1 ATOM 5904 C CZ2 . TRP B 1 349 ? 11.102 -39.616 17.365 1.00 68.85 ? 349 TRP B CZ2 1 ATOM 5905 C CZ3 . TRP B 1 349 ? 9.652 -37.921 16.440 1.00 62.66 ? 349 TRP B CZ3 1 ATOM 5906 C CH2 . TRP B 1 349 ? 10.401 -39.095 16.311 1.00 60.27 ? 349 TRP B CH2 1 ATOM 5907 N N . GLN B 1 350 ? 10.966 -33.283 22.127 1.00 39.10 ? 350 GLN B N 1 ATOM 5908 C CA . GLN B 1 350 ? 10.619 -31.881 22.327 1.00 43.07 ? 350 GLN B CA 1 ATOM 5909 C C . GLN B 1 350 ? 9.740 -31.401 21.179 1.00 37.33 ? 350 GLN B C 1 ATOM 5910 O O . GLN B 1 350 ? 10.021 -31.681 20.008 1.00 41.66 ? 350 GLN B O 1 ATOM 5911 C CB . GLN B 1 350 ? 11.876 -31.014 22.422 1.00 35.52 ? 350 GLN B CB 1 ATOM 5912 C CG . GLN B 1 350 ? 12.871 -31.421 23.498 1.00 42.31 ? 350 GLN B CG 1 ATOM 5913 C CD . GLN B 1 350 ? 12.502 -30.953 24.907 1.00 39.16 ? 350 GLN B CD 1 ATOM 5914 O OE1 . GLN B 1 350 ? 11.440 -30.372 25.138 1.00 34.69 ? 350 GLN B OE1 1 ATOM 5915 N NE2 . GLN B 1 350 ? 13.388 -31.216 25.854 1.00 31.72 ? 350 GLN B NE2 1 ATOM 5916 N N . ARG B 1 351 ? 8.674 -30.674 21.519 1.00 34.40 ? 351 ARG B N 1 ATOM 5917 C CA . ARG B 1 351 ? 7.732 -30.167 20.534 1.00 33.06 ? 351 ARG B CA 1 ATOM 5918 C C . ARG B 1 351 ? 7.793 -28.658 20.338 1.00 34.33 ? 351 ARG B C 1 ATOM 5919 O O . ARG B 1 351 ? 7.286 -28.164 19.328 1.00 33.79 ? 351 ARG B O 1 ATOM 5920 C CB . ARG B 1 351 ? 6.301 -30.558 20.924 1.00 35.65 ? 351 ARG B CB 1 ATOM 5921 C CG . ARG B 1 351 ? 6.081 -32.051 21.047 1.00 37.56 ? 351 ARG B CG 1 ATOM 5922 C CD . ARG B 1 351 ? 6.447 -32.763 19.759 1.00 49.88 ? 351 ARG B CD 1 ATOM 5923 N NE . ARG B 1 351 ? 5.486 -33.813 19.433 1.00 63.82 ? 351 ARG B NE 1 ATOM 5924 C CZ . ARG B 1 351 ? 5.487 -34.503 18.296 1.00 69.64 ? 351 ARG B CZ 1 ATOM 5925 N NH1 . ARG B 1 351 ? 6.404 -34.258 17.365 1.00 67.10 ? 351 ARG B NH1 1 ATOM 5926 N NH2 . ARG B 1 351 ? 4.569 -35.437 18.089 1.00 71.21 ? 351 ARG B NH2 1 ATOM 5927 N N . GLY B 1 352 ? 8.385 -27.919 21.269 1.00 33.17 ? 352 GLY B N 1 ATOM 5928 C CA . GLY B 1 352 ? 8.551 -26.489 21.103 1.00 29.19 ? 352 GLY B CA 1 ATOM 5929 C C . GLY B 1 352 ? 9.943 -26.047 21.499 1.00 29.57 ? 352 GLY B C 1 ATOM 5930 O O . GLY B 1 352 ? 10.603 -26.668 22.334 1.00 29.82 ? 352 GLY B O 1 ATOM 5931 N N . TRP B 1 353 ? 10.390 -24.956 20.882 1.00 28.30 ? 353 TRP B N 1 ATOM 5932 C CA . TRP B 1 353 ? 11.715 -24.432 21.190 1.00 25.67 ? 353 TRP B CA 1 ATOM 5933 C C . TRP B 1 353 ? 11.758 -22.951 20.849 1.00 25.67 ? 353 TRP B C 1 ATOM 5934 O O . TRP B 1 353 ? 10.779 -22.371 20.370 1.00 26.33 ? 353 TRP B O 1 ATOM 5935 C CB . TRP B 1 353 ? 12.802 -25.201 20.439 1.00 32.27 ? 353 TRP B CB 1 ATOM 5936 C CG . TRP B 1 353 ? 14.098 -25.343 21.176 1.00 27.22 ? 353 TRP B CG 1 ATOM 5937 C CD1 . TRP B 1 353 ? 15.224 -24.580 21.020 1.00 28.91 ? 353 TRP B CD1 1 ATOM 5938 C CD2 . TRP B 1 353 ? 14.418 -26.329 22.167 1.00 28.68 ? 353 TRP B CD2 1 ATOM 5939 N NE1 . TRP B 1 353 ? 16.221 -25.035 21.853 1.00 32.38 ? 353 TRP B NE1 1 ATOM 5940 C CE2 . TRP B 1 353 ? 15.748 -26.103 22.570 1.00 30.43 ? 353 TRP B CE2 1 ATOM 5941 C CE3 . TRP B 1 353 ? 13.704 -27.377 22.754 1.00 33.10 ? 353 TRP B CE3 1 ATOM 5942 C CZ2 . TRP B 1 353 ? 16.379 -26.887 23.534 1.00 30.25 ? 353 TRP B CZ2 1 ATOM 5943 C CZ3 . TRP B 1 353 ? 14.331 -28.151 23.718 1.00 38.38 ? 353 TRP B CZ3 1 ATOM 5944 C CH2 . TRP B 1 353 ? 15.655 -27.902 24.096 1.00 30.54 ? 353 TRP B CH2 1 ATOM 5945 N N . HIS B 1 354 ? 12.911 -22.346 21.119 1.00 28.79 ? 354 HIS B N 1 ATOM 5946 C CA . HIS B 1 354 ? 13.121 -20.910 20.969 1.00 25.83 ? 354 HIS B CA 1 ATOM 5947 C C . HIS B 1 354 ? 14.626 -20.675 20.911 1.00 26.64 ? 354 HIS B C 1 ATOM 5948 O O . HIS B 1 354 ? 15.422 -21.576 21.180 1.00 32.37 ? 354 HIS B O 1 ATOM 5949 C CB . HIS B 1 354 ? 12.464 -20.142 22.126 1.00 26.98 ? 354 HIS B CB 1 ATOM 5950 C CG . HIS B 1 354 ? 13.024 -20.518 23.463 1.00 27.33 ? 354 HIS B CG 1 ATOM 5951 N ND1 . HIS B 1 354 ? 14.198 -19.983 23.945 1.00 24.10 ? 354 HIS B ND1 1 ATOM 5952 C CD2 . HIS B 1 354 ? 12.610 -21.414 24.391 1.00 26.44 ? 354 HIS B CD2 1 ATOM 5953 C CE1 . HIS B 1 354 ? 14.484 -20.531 25.111 1.00 27.62 ? 354 HIS B CE1 1 ATOM 5954 N NE2 . HIS B 1 354 ? 13.531 -21.391 25.412 1.00 29.18 ? 354 HIS B NE2 1 ATOM 5955 N N . GLY B 1 355 ? 15.018 -19.444 20.601 1.00 24.87 ? 355 GLY B N 1 ATOM 5956 C CA . GLY B 1 355 ? 16.403 -19.091 20.357 1.00 26.14 ? 355 GLY B CA 1 ATOM 5957 C C . GLY B 1 355 ? 16.640 -18.489 18.988 1.00 29.78 ? 355 GLY B C 1 ATOM 5958 O O . GLY B 1 355 ? 17.632 -17.764 18.794 1.00 30.68 ? 355 GLY B O 1 ATOM 5959 N N . TYR B 1 356 ? 15.722 -18.725 18.053 1.00 31.24 ? 356 TYR B N 1 ATOM 5960 C CA . TYR B 1 356 ? 15.808 -18.248 16.679 1.00 28.55 ? 356 TYR B CA 1 ATOM 5961 C C . TYR B 1 356 ? 15.864 -16.727 16.584 1.00 32.14 ? 356 TYR B C 1 ATOM 5962 O O . TYR B 1 356 ? 15.665 -16.030 17.586 1.00 29.96 ? 356 TYR B O 1 ATOM 5963 C CB . TYR B 1 356 ? 14.605 -18.748 15.895 1.00 25.72 ? 356 TYR B CB 1 ATOM 5964 C CG . TYR B 1 356 ? 14.383 -20.238 15.931 1.00 30.36 ? 356 TYR B CG 1 ATOM 5965 C CD1 . TYR B 1 356 ? 15.073 -21.090 15.064 1.00 29.63 ? 356 TYR B CD1 1 ATOM 5966 C CD2 . TYR B 1 356 ? 13.458 -20.795 16.798 1.00 27.32 ? 356 TYR B CD2 1 ATOM 5967 C CE1 . TYR B 1 356 ? 14.851 -22.459 15.083 1.00 26.49 ? 356 TYR B CE1 1 ATOM 5968 C CE2 . TYR B 1 356 ? 13.228 -22.160 16.825 1.00 31.25 ? 356 TYR B CE2 1 ATOM 5969 C CZ . TYR B 1 356 ? 13.924 -22.986 15.964 1.00 31.86 ? 356 TYR B CZ 1 ATOM 5970 O OH . TYR B 1 356 ? 13.686 -24.340 16.001 1.00 34.60 ? 356 TYR B OH 1 ATOM 5971 N N . ASP B 1 357 ? 16.142 -16.224 15.372 1.00 30.76 ? 357 ASP B N 1 ATOM 5972 C CA . ASP B 1 357 ? 16.015 -14.823 14.966 1.00 25.10 ? 357 ASP B CA 1 ATOM 5973 C C . ASP B 1 357 ? 15.017 -14.081 15.846 1.00 27.02 ? 357 ASP B C 1 ATOM 5974 O O . ASP B 1 357 ? 13.853 -14.484 15.942 1.00 27.13 ? 357 ASP B O 1 ATOM 5975 C CB . ASP B 1 357 ? 15.584 -14.779 13.492 1.00 29.85 ? 357 ASP B CB 1 ATOM 5976 C CG . ASP B 1 357 ? 15.559 -13.379 12.909 1.00 33.91 ? 357 ASP B CG 1 ATOM 5977 O OD1 . ASP B 1 357 ? 15.622 -12.380 13.660 1.00 31.21 ? 357 ASP B OD1 1 ATOM 5978 O OD2 . ASP B 1 357 ? 15.457 -13.283 11.668 1.00 35.40 ? 357 ASP B OD2 1 ATOM 5979 N N . ASN B 1 358 ? 15.464 -13.012 16.511 1.00 25.34 ? 358 ASN B N 1 ATOM 5980 C CA . ASN B 1 358 ? 14.632 -12.409 17.549 1.00 29.54 ? 358 ASN B CA 1 ATOM 5981 C C . ASN B 1 358 ? 13.494 -11.582 16.980 1.00 30.41 ? 358 ASN B C 1 ATOM 5982 O O . ASN B 1 358 ? 12.623 -11.161 17.747 1.00 25.72 ? 358 ASN B O 1 ATOM 5983 C CB . ASN B 1 358 ? 15.470 -11.532 18.481 1.00 24.95 ? 358 ASN B CB 1 ATOM 5984 C CG . ASN B 1 358 ? 16.172 -10.409 17.749 1.00 27.49 ? 358 ASN B CG 1 ATOM 5985 O OD1 . ASN B 1 358 ? 16.694 -10.611 16.656 1.00 23.91 ? 358 ASN B OD1 1 ATOM 5986 N ND2 . ASN B 1 358 ? 16.190 -9.209 18.350 1.00 26.45 ? 358 ASN B ND2 1 ATOM 5987 N N . GLU B 1 359 ? 13.476 -11.339 15.671 1.00 25.02 ? 359 GLU B N 1 ATOM 5988 C CA . GLU B 1 359 ? 12.381 -10.591 15.067 1.00 25.43 ? 359 GLU B CA 1 ATOM 5989 C C . GLU B 1 359 ? 11.261 -11.487 14.552 1.00 25.88 ? 359 GLU B C 1 ATOM 5990 O O . GLU B 1 359 ? 10.269 -10.972 14.023 1.00 29.16 ? 359 GLU B O 1 ATOM 5991 C CB . GLU B 1 359 ? 12.909 -9.687 13.940 1.00 28.78 ? 359 GLU B CB 1 ATOM 5992 C CG . GLU B 1 359 ? 13.915 -8.615 14.390 1.00 23.75 ? 359 GLU B CG 1 ATOM 5993 C CD . GLU B 1 359 ? 13.294 -7.449 15.157 1.00 34.41 ? 359 GLU B CD 1 ATOM 5994 O OE1 . GLU B 1 359 ? 12.045 -7.317 15.196 1.00 30.07 ? 359 GLU B OE1 1 ATOM 5995 O OE2 . GLU B 1 359 ? 14.072 -6.653 15.725 1.00 34.92 ? 359 GLU B OE2 1 ATOM 5996 N N . LEU B 1 360 ? 11.372 -12.802 14.721 1.00 25.29 ? 360 LEU B N 1 ATOM 5997 C CA . LEU B 1 360 ? 10.267 -13.689 14.393 1.00 23.56 ? 360 LEU B CA 1 ATOM 5998 C C . LEU B 1 360 ? 9.105 -13.465 15.352 1.00 30.50 ? 360 LEU B C 1 ATOM 5999 O O . LEU B 1 360 ? 9.294 -13.315 16.566 1.00 27.29 ? 360 LEU B O 1 ATOM 6000 C CB . LEU B 1 360 ? 10.716 -15.145 14.448 1.00 23.21 ? 360 LEU B CB 1 ATOM 6001 C CG . LEU B 1 360 ? 11.794 -15.483 13.419 1.00 32.36 ? 360 LEU B CG 1 ATOM 6002 C CD1 . LEU B 1 360 ? 12.419 -16.840 13.710 1.00 30.53 ? 360 LEU B CD1 1 ATOM 6003 C CD2 . LEU B 1 360 ? 11.205 -15.478 12.013 1.00 33.03 ? 360 LEU B CD2 1 ATOM 6004 N N . MET B 1 361 ? 7.897 -13.446 14.789 1.00 27.40 ? 361 MET B N 1 ATOM 6005 C CA . MET B 1 361 ? 6.688 -13.279 15.590 1.00 31.99 ? 361 MET B CA 1 ATOM 6006 C C . MET B 1 361 ? 6.618 -14.271 16.750 1.00 26.24 ? 361 MET B C 1 ATOM 6007 O O . MET B 1 361 ? 6.206 -13.910 17.860 1.00 26.96 ? 361 MET B O 1 ATOM 6008 C CB . MET B 1 361 ? 5.451 -13.423 14.697 1.00 29.54 ? 361 MET B CB 1 ATOM 6009 C CG . MET B 1 361 ? 4.171 -13.208 15.463 1.00 32.81 ? 361 MET B CG 1 ATOM 6010 S SD . MET B 1 361 ? 2.695 -13.340 14.457 1.00 36.33 ? 361 MET B SD 1 ATOM 6011 C CE . MET B 1 361 ? 1.462 -13.258 15.752 1.00 34.59 ? 361 MET B CE 1 ATOM 6012 N N . ASP B 1 362 ? 6.982 -15.534 16.511 1.00 24.09 ? 362 ASP B N 1 ATOM 6013 C CA . ASP B 1 362 ? 6.840 -16.533 17.567 1.00 25.97 ? 362 ASP B CA 1 ATOM 6014 C C . ASP B 1 362 ? 7.823 -16.319 18.717 1.00 26.33 ? 362 ASP B C 1 ATOM 6015 O O . ASP B 1 362 ? 7.632 -16.901 19.795 1.00 25.17 ? 362 ASP B O 1 ATOM 6016 C CB . ASP B 1 362 ? 7.018 -17.947 17.004 1.00 27.22 ? 362 ASP B CB 1 ATOM 6017 C CG . ASP B 1 362 ? 5.785 -18.451 16.257 1.00 33.14 ? 362 ASP B CG 1 ATOM 6018 O OD1 . ASP B 1 362 ? 4.747 -17.749 16.248 1.00 32.36 ? 362 ASP B OD1 1 ATOM 6019 O OD2 . ASP B 1 362 ? 5.849 -19.576 15.700 1.00 35.88 ? 362 ASP B OD2 1 ATOM 6020 N N . MET B 1 363 ? 8.872 -15.525 18.517 1.00 25.27 ? 363 MET B N 1 ATOM 6021 C CA . MET B 1 363 ? 9.842 -15.269 19.576 1.00 30.05 ? 363 MET B CA 1 ATOM 6022 C C . MET B 1 363 ? 9.458 -14.086 20.456 1.00 27.59 ? 363 MET B C 1 ATOM 6023 O O . MET B 1 363 ? 10.136 -13.832 21.454 1.00 22.61 ? 363 MET B O 1 ATOM 6024 C CB . MET B 1 363 ? 11.240 -15.043 18.981 1.00 25.34 ? 363 MET B CB 1 ATOM 6025 C CG . MET B 1 363 ? 11.823 -16.259 18.240 1.00 25.81 ? 363 MET B CG 1 ATOM 6026 S SD . MET B 1 363 ? 12.022 -17.738 19.266 1.00 26.51 ? 363 MET B SD 1 ATOM 6027 C CE . MET B 1 363 ? 10.487 -18.617 18.921 1.00 26.70 ? 363 MET B CE 1 ATOM 6028 N N . ARG B 1 364 ? 8.395 -13.361 20.110 1.00 22.73 ? 364 ARG B N 1 ATOM 6029 C CA . ARG B 1 364 ? 7.975 -12.221 20.907 1.00 24.61 ? 364 ARG B CA 1 ATOM 6030 C C . ARG B 1 364 ? 7.550 -12.658 22.304 1.00 18.80 ? 364 ARG B C 1 ATOM 6031 O O . ARG B 1 364 ? 6.890 -13.685 22.469 1.00 20.63 ? 364 ARG B O 1 ATOM 6032 C CB . ARG B 1 364 ? 6.796 -11.514 20.240 1.00 23.10 ? 364 ARG B CB 1 ATOM 6033 C CG . ARG B 1 364 ? 7.088 -10.971 18.837 1.00 23.87 ? 364 ARG B CG 1 ATOM 6034 C CD . ARG B 1 364 ? 5.798 -10.482 18.173 1.00 25.77 ? 364 ARG B CD 1 ATOM 6035 N NE . ARG B 1 364 ? 6.079 -9.895 16.867 1.00 27.72 ? 364 ARG B NE 1 ATOM 6036 C CZ . ARG B 1 364 ? 5.150 -9.507 16.000 1.00 29.01 ? 364 ARG B CZ 1 ATOM 6037 N NH1 . ARG B 1 364 ? 3.865 -9.633 16.295 1.00 26.96 ? 364 ARG B NH1 1 ATOM 6038 N NH2 . ARG B 1 364 ? 5.517 -8.992 14.837 1.00 26.25 ? 364 ARG B NH2 1 ATOM 6039 N N . GLY B 1 365 ? 7.888 -11.834 23.297 1.00 19.73 ? 365 GLY B N 1 ATOM 6040 C CA . GLY B 1 365 ? 7.444 -11.998 24.662 1.00 24.24 ? 365 GLY B CA 1 ATOM 6041 C C . GLY B 1 365 ? 6.432 -10.941 25.064 1.00 21.61 ? 365 GLY B C 1 ATOM 6042 O O . GLY B 1 365 ? 5.793 -10.300 24.224 1.00 21.92 ? 365 GLY B O 1 ATOM 6043 N N . ILE B 1 366 ? 6.279 -10.757 26.379 1.00 19.89 ? 366 ILE B N 1 ATOM 6044 C CA . ILE B 1 366 ? 5.246 -9.875 26.909 1.00 22.53 ? 366 ILE B CA 1 ATOM 6045 C C . ILE B 1 366 ? 5.853 -8.836 27.842 1.00 20.39 ? 366 ILE B C 1 ATOM 6046 O O . ILE B 1 366 ? 6.934 -9.019 28.410 1.00 21.21 ? 366 ILE B O 1 ATOM 6047 C CB . ILE B 1 366 ? 4.144 -10.644 27.661 1.00 17.80 ? 366 ILE B CB 1 ATOM 6048 C CG1 . ILE B 1 366 ? 4.772 -11.406 28.852 1.00 16.60 ? 366 ILE B CG1 1 ATOM 6049 C CG2 . ILE B 1 366 ? 3.403 -11.590 26.736 1.00 18.20 ? 366 ILE B CG2 1 ATOM 6050 C CD1 . ILE B 1 366 ? 3.736 -11.804 29.921 1.00 25.00 ? 366 ILE B CD1 1 ATOM 6051 N N . PHE B 1 367 ? 5.107 -7.746 28.032 1.00 17.58 ? 367 PHE B N 1 ATOM 6052 C CA . PHE B 1 367 ? 5.396 -6.795 29.100 1.00 17.61 ? 367 PHE B CA 1 ATOM 6053 C C . PHE B 1 367 ? 4.092 -6.162 29.564 1.00 21.93 ? 367 PHE B C 1 ATOM 6054 O O . PHE B 1 367 ? 3.330 -5.628 28.747 1.00 21.55 ? 367 PHE B O 1 ATOM 6055 C CB . PHE B 1 367 ? 6.377 -5.693 28.663 1.00 18.12 ? 367 PHE B CB 1 ATOM 6056 C CG . PHE B 1 367 ? 6.611 -4.632 29.724 1.00 17.66 ? 367 PHE B CG 1 ATOM 6057 C CD1 . PHE B 1 367 ? 5.695 -3.584 29.897 1.00 20.61 ? 367 PHE B CD1 1 ATOM 6058 C CD2 . PHE B 1 367 ? 7.728 -4.674 30.540 1.00 17.82 ? 367 PHE B CD2 1 ATOM 6059 C CE1 . PHE B 1 367 ? 5.893 -2.623 30.868 1.00 20.73 ? 367 PHE B CE1 1 ATOM 6060 C CE2 . PHE B 1 367 ? 7.953 -3.706 31.507 1.00 19.87 ? 367 PHE B CE2 1 ATOM 6061 C CZ . PHE B 1 367 ? 7.022 -2.668 31.674 1.00 22.74 ? 367 PHE B CZ 1 ATOM 6062 N N . LEU B 1 368 ? 3.864 -6.191 30.876 1.00 20.22 ? 368 LEU B N 1 ATOM 6063 C CA . LEU B 1 368 ? 2.707 -5.547 31.490 1.00 22.85 ? 368 LEU B CA 1 ATOM 6064 C C . LEU B 1 368 ? 3.157 -4.871 32.775 1.00 21.63 ? 368 LEU B C 1 ATOM 6065 O O . LEU B 1 368 ? 4.177 -5.240 33.366 1.00 20.26 ? 368 LEU B O 1 ATOM 6066 C CB . LEU B 1 368 ? 1.577 -6.538 31.804 1.00 25.73 ? 368 LEU B CB 1 ATOM 6067 C CG . LEU B 1 368 ? 0.975 -7.316 30.633 1.00 27.04 ? 368 LEU B CG 1 ATOM 6068 C CD1 . LEU B 1 368 ? 1.647 -8.666 30.545 1.00 24.19 ? 368 LEU B CD1 1 ATOM 6069 C CD2 . LEU B 1 368 ? -0.525 -7.463 30.818 1.00 27.72 ? 368 LEU B CD2 1 ATOM 6070 N N . ALA B 1 369 ? 2.390 -3.865 33.202 1.00 18.62 ? 369 ALA B N 1 ATOM 6071 C CA . ALA B 1 369 ? 2.691 -3.182 34.454 1.00 18.76 ? 369 ALA B CA 1 ATOM 6072 C C . ALA B 1 369 ? 1.422 -2.588 35.045 1.00 28.27 ? 369 ALA B C 1 ATOM 6073 O O . ALA B 1 369 ? 0.494 -2.205 34.317 1.00 24.54 ? 369 ALA B O 1 ATOM 6074 C CB . ALA B 1 369 ? 3.737 -2.086 34.267 1.00 24.45 ? 369 ALA B CB 1 ATOM 6075 N N . ILE B 1 370 ? 1.394 -2.504 36.374 1.00 23.47 ? 370 ILE B N 1 ATOM 6076 C CA . ILE B 1 370 ? 0.206 -2.026 37.079 1.00 24.77 ? 370 ILE B CA 1 ATOM 6077 C C . ILE B 1 370 ? 0.632 -1.410 38.407 1.00 30.11 ? 370 ILE B C 1 ATOM 6078 O O . ILE B 1 370 ? 1.544 -1.904 39.083 1.00 23.01 ? 370 ILE B O 1 ATOM 6079 C CB . ILE B 1 370 ? -0.837 -3.155 37.266 1.00 22.52 ? 370 ILE B CB 1 ATOM 6080 C CG1 . ILE B 1 370 ? -2.139 -2.602 37.864 1.00 26.52 ? 370 ILE B CG1 1 ATOM 6081 C CG2 . ILE B 1 370 ? -0.287 -4.308 38.122 1.00 21.15 ? 370 ILE B CG2 1 ATOM 6082 C CD1 . ILE B 1 370 ? -3.291 -3.593 37.808 1.00 30.02 ? 370 ILE B CD1 1 ATOM 6083 N N . GLY B 1 371 ? -0.034 -0.315 38.777 1.00 22.80 ? 371 GLY B N 1 ATOM 6084 C CA . GLY B 1 371 ? 0.254 0.366 40.016 1.00 25.73 ? 371 GLY B CA 1 ATOM 6085 C C . GLY B 1 371 ? 0.136 1.872 39.856 1.00 29.40 ? 371 GLY B C 1 ATOM 6086 O O . GLY B 1 371 ? -0.115 2.381 38.762 1.00 26.16 ? 371 GLY B O 1 ATOM 6087 N N . PRO B 1 372 ? 0.350 2.610 40.948 1.00 31.09 ? 372 PRO B N 1 ATOM 6088 C CA . PRO B 1 372 ? 0.136 4.070 40.919 1.00 33.61 ? 372 PRO B CA 1 ATOM 6089 C C . PRO B 1 372 ? 0.946 4.820 39.872 1.00 34.88 ? 372 PRO B C 1 ATOM 6090 O O . PRO B 1 372 ? 0.497 5.879 39.408 1.00 33.18 ? 372 PRO B O 1 ATOM 6091 C CB . PRO B 1 372 ? 0.529 4.502 42.338 1.00 28.79 ? 372 PRO B CB 1 ATOM 6092 C CG . PRO B 1 372 ? 0.374 3.294 43.165 1.00 37.80 ? 372 PRO B CG 1 ATOM 6093 C CD . PRO B 1 372 ? 0.733 2.130 42.284 1.00 30.25 ? 372 PRO B CD 1 ATOM 6094 N N . ASP B 1 373 ? 2.112 4.321 39.469 1.00 28.68 ? 373 ASP B N 1 ATOM 6095 C CA . ASP B 1 373 ? 2.931 5.020 38.485 1.00 28.64 ? 373 ASP B CA 1 ATOM 6096 C C . ASP B 1 373 ? 2.589 4.666 37.044 1.00 34.20 ? 373 ASP B C 1 ATOM 6097 O O . ASP B 1 373 ? 3.165 5.258 36.120 1.00 32.32 ? 373 ASP B O 1 ATOM 6098 C CB . ASP B 1 373 ? 4.418 4.752 38.750 1.00 33.22 ? 373 ASP B CB 1 ATOM 6099 C CG . ASP B 1 373 ? 4.915 5.471 39.985 1.00 37.73 ? 373 ASP B CG 1 ATOM 6100 O OD1 . ASP B 1 373 ? 4.991 6.720 39.947 1.00 39.39 ? 373 ASP B OD1 1 ATOM 6101 O OD2 . ASP B 1 373 ? 5.216 4.797 40.996 1.00 35.67 ? 373 ASP B OD2 1 ATOM 6102 N N . PHE B 1 374 ? 1.656 3.748 36.816 1.00 25.00 ? 374 PHE B N 1 ATOM 6103 C CA . PHE B 1 374 ? 1.333 3.332 35.463 1.00 25.89 ? 374 PHE B CA 1 ATOM 6104 C C . PHE B 1 374 ? -0.094 3.715 35.115 1.00 25.06 ? 374 PHE B C 1 ATOM 6105 O O . PHE B 1 374 ? -0.982 3.704 35.974 1.00 32.06 ? 374 PHE B O 1 ATOM 6106 C CB . PHE B 1 374 ? 1.555 1.832 35.292 1.00 24.72 ? 374 PHE B CB 1 ATOM 6107 C CG . PHE B 1 374 ? 3.004 1.446 35.397 1.00 23.43 ? 374 PHE B CG 1 ATOM 6108 C CD1 . PHE B 1 374 ? 3.843 1.561 34.295 1.00 25.33 ? 374 PHE B CD1 1 ATOM 6109 C CD2 . PHE B 1 374 ? 3.529 1.005 36.600 1.00 27.44 ? 374 PHE B CD2 1 ATOM 6110 C CE1 . PHE B 1 374 ? 5.184 1.221 34.379 1.00 28.68 ? 374 PHE B CE1 1 ATOM 6111 C CE2 . PHE B 1 374 ? 4.875 0.674 36.701 1.00 24.33 ? 374 PHE B CE2 1 ATOM 6112 C CZ . PHE B 1 374 ? 5.702 0.773 35.589 1.00 21.32 ? 374 PHE B CZ 1 ATOM 6113 N N . LYS B 1 375 ? -0.289 4.077 33.850 1.00 32.39 ? 375 LYS B N 1 ATOM 6114 C CA . LYS B 1 375 ? -1.615 4.361 33.329 1.00 31.99 ? 375 LYS B CA 1 ATOM 6115 C C . LYS B 1 375 ? -2.471 3.100 33.345 1.00 37.21 ? 375 LYS B C 1 ATOM 6116 O O . LYS B 1 375 ? -1.967 1.975 33.320 1.00 33.10 ? 375 LYS B O 1 ATOM 6117 C CB . LYS B 1 375 ? -1.518 4.908 31.910 1.00 28.99 ? 375 LYS B CB 1 ATOM 6118 C CG . LYS B 1 375 ? -1.005 6.326 31.831 1.00 33.05 ? 375 LYS B CG 1 ATOM 6119 C CD . LYS B 1 375 ? -0.835 6.745 30.388 1.00 31.81 ? 375 LYS B CD 1 ATOM 6120 C CE . LYS B 1 375 ? -0.260 8.143 30.298 1.00 29.07 ? 375 LYS B CE 1 ATOM 6121 N NZ . LYS B 1 375 ? 0.009 8.514 28.893 1.00 32.90 ? 375 LYS B NZ 1 ATOM 6122 N N . SER B 1 376 ? -3.787 3.291 33.400 1.00 31.96 ? 376 SER B N 1 ATOM 6123 C CA . SER B 1 376 ? -4.711 2.170 33.480 1.00 29.94 ? 376 SER B CA 1 ATOM 6124 C C . SER B 1 376 ? -5.468 2.029 32.168 1.00 38.78 ? 376 SER B C 1 ATOM 6125 O O . SER B 1 376 ? -5.813 3.029 31.524 1.00 32.31 ? 376 SER B O 1 ATOM 6126 C CB . SER B 1 376 ? -5.682 2.328 34.656 1.00 34.05 ? 376 SER B CB 1 ATOM 6127 O OG . SER B 1 376 ? -6.261 3.622 34.673 1.00 50.59 ? 376 SER B OG 1 ATOM 6128 N N . ASN B 1 377 ? -5.687 0.776 31.764 1.00 31.91 ? 377 ASN B N 1 ATOM 6129 C CA . ASN B 1 377 ? -6.367 0.447 30.510 1.00 35.63 ? 377 ASN B CA 1 ATOM 6130 C C . ASN B 1 377 ? -5.637 1.040 29.306 1.00 35.96 ? 377 ASN B C 1 ATOM 6131 O O . ASN B 1 377 ? -6.254 1.543 28.368 1.00 37.07 ? 377 ASN B O 1 ATOM 6132 C CB . ASN B 1 377 ? -7.830 0.900 30.542 1.00 37.45 ? 377 ASN B CB 1 ATOM 6133 C CG . ASN B 1 377 ? -8.699 0.122 29.576 1.00 38.83 ? 377 ASN B CG 1 ATOM 6134 O OD1 . ASN B 1 377 ? -8.373 -1.002 29.199 1.00 34.94 ? 377 ASN B OD1 1 ATOM 6135 N ND2 . ASN B 1 377 ? -9.813 0.721 29.166 1.00 41.79 ? 377 ASN B ND2 1 ATOM 6136 N N . PHE B 1 378 ? -4.312 0.958 29.323 1.00 28.26 ? 378 PHE B N 1 ATOM 6137 C CA . PHE B 1 378 ? -3.457 1.633 28.358 1.00 26.58 ? 378 PHE B CA 1 ATOM 6138 C C . PHE B 1 378 ? -2.737 0.588 27.509 1.00 37.20 ? 378 PHE B C 1 ATOM 6139 O O . PHE B 1 378 ? -1.940 -0.202 28.037 1.00 27.56 ? 378 PHE B O 1 ATOM 6140 C CB . PHE B 1 378 ? -2.466 2.535 29.097 1.00 27.26 ? 378 PHE B CB 1 ATOM 6141 C CG . PHE B 1 378 ? -1.561 3.326 28.201 1.00 32.86 ? 378 PHE B CG 1 ATOM 6142 C CD1 . PHE B 1 378 ? -1.933 4.598 27.768 1.00 31.29 ? 378 PHE B CD1 1 ATOM 6143 C CD2 . PHE B 1 378 ? -0.332 2.820 27.809 1.00 29.36 ? 378 PHE B CD2 1 ATOM 6144 C CE1 . PHE B 1 378 ? -1.103 5.340 26.963 1.00 28.76 ? 378 PHE B CE1 1 ATOM 6145 C CE2 . PHE B 1 378 ? 0.503 3.553 26.988 1.00 27.92 ? 378 PHE B CE2 1 ATOM 6146 C CZ . PHE B 1 378 ? 0.116 4.824 26.567 1.00 29.62 ? 378 PHE B CZ 1 ATOM 6147 N N . ARG B 1 379 ? -3.021 0.577 26.198 1.00 29.53 ? 379 ARG B N 1 ATOM 6148 C CA . ARG B 1 379 ? -2.355 -0.320 25.250 1.00 34.28 ? 379 ARG B CA 1 ATOM 6149 C C . ARG B 1 379 ? -1.128 0.384 24.679 1.00 35.33 ? 379 ARG B C 1 ATOM 6150 O O . ARG B 1 379 ? -1.254 1.345 23.913 1.00 35.07 ? 379 ARG B O 1 ATOM 6151 C CB . ARG B 1 379 ? -3.298 -0.744 24.124 1.00 34.73 ? 379 ARG B CB 1 ATOM 6152 C CG . ARG B 1 379 ? -4.605 -1.339 24.593 1.00 37.36 ? 379 ARG B CG 1 ATOM 6153 C CD . ARG B 1 379 ? -4.407 -2.616 25.417 1.00 40.75 ? 379 ARG B CD 1 ATOM 6154 N NE . ARG B 1 379 ? -5.688 -3.298 25.593 1.00 44.12 ? 379 ARG B NE 1 ATOM 6155 C CZ . ARG B 1 379 ? -6.549 -3.033 26.573 1.00 43.41 ? 379 ARG B CZ 1 ATOM 6156 N NH1 . ARG B 1 379 ? -6.250 -2.125 27.490 1.00 33.82 ? 379 ARG B NH1 1 ATOM 6157 N NH2 . ARG B 1 379 ? -7.704 -3.690 26.648 1.00 39.77 ? 379 ARG B NH2 1 ATOM 6158 N N . ALA B 1 380 ? 0.060 -0.092 25.045 1.00 27.79 ? 380 ALA B N 1 ATOM 6159 C CA . ALA B 1 380 ? 1.298 0.548 24.624 1.00 23.90 ? 380 ALA B CA 1 ATOM 6160 C C . ALA B 1 380 ? 1.820 -0.090 23.347 1.00 26.52 ? 380 ALA B C 1 ATOM 6161 O O . ALA B 1 380 ? 1.569 -1.266 23.074 1.00 24.27 ? 380 ALA B O 1 ATOM 6162 C CB . ALA B 1 380 ? 2.362 0.455 25.724 1.00 28.49 ? 380 ALA B CB 1 ATOM 6163 N N . ALA B 1 381 ? 2.538 0.715 22.552 1.00 27.37 ? 381 ALA B N 1 ATOM 6164 C CA . ALA B 1 381 ? 3.252 0.214 21.391 1.00 23.80 ? 381 ALA B CA 1 ATOM 6165 C C . ALA B 1 381 ? 4.316 -0.791 21.818 1.00 24.64 ? 381 ALA B C 1 ATOM 6166 O O . ALA B 1 381 ? 4.791 -0.756 22.954 1.00 25.25 ? 381 ALA B O 1 ATOM 6167 C CB . ALA B 1 381 ? 3.912 1.358 20.629 1.00 27.48 ? 381 ALA B CB 1 ATOM 6168 N N . PRO B 1 382 ? 4.712 -1.694 20.917 1.00 26.77 ? 382 PRO B N 1 ATOM 6169 C CA . PRO B 1 382 ? 5.710 -2.712 21.289 1.00 24.05 ? 382 PRO B CA 1 ATOM 6170 C C . PRO B 1 382 ? 7.054 -2.102 21.645 1.00 25.69 ? 382 PRO B C 1 ATOM 6171 O O . PRO B 1 382 ? 7.483 -1.095 21.081 1.00 25.14 ? 382 PRO B O 1 ATOM 6172 C CB . PRO B 1 382 ? 5.818 -3.590 20.038 1.00 24.85 ? 382 PRO B CB 1 ATOM 6173 C CG . PRO B 1 382 ? 5.304 -2.723 18.919 1.00 25.77 ? 382 PRO B CG 1 ATOM 6174 C CD . PRO B 1 382 ? 4.247 -1.859 19.531 1.00 24.77 ? 382 PRO B CD 1 ATOM 6175 N N . ILE B 1 383 ? 7.728 -2.743 22.601 1.00 21.82 ? 383 ILE B N 1 ATOM 6176 C CA . ILE B 1 383 ? 9.013 -2.285 23.096 1.00 25.46 ? 383 ILE B CA 1 ATOM 6177 C C . ILE B 1 383 ? 10.000 -3.434 22.963 1.00 18.74 ? 383 ILE B C 1 ATOM 6178 O O . ILE B 1 383 ? 9.635 -4.568 22.640 1.00 20.72 ? 383 ILE B O 1 ATOM 6179 C CB . ILE B 1 383 ? 8.936 -1.780 24.552 1.00 25.31 ? 383 ILE B CB 1 ATOM 6180 C CG1 . ILE B 1 383 ? 8.737 -2.954 25.511 1.00 22.60 ? 383 ILE B CG1 1 ATOM 6181 C CG2 . ILE B 1 383 ? 7.789 -0.765 24.685 1.00 28.54 ? 383 ILE B CG2 1 ATOM 6182 C CD1 . ILE B 1 383 ? 8.681 -2.559 26.983 1.00 24.28 ? 383 ILE B CD1 1 ATOM 6183 N N . ARG B 1 384 ? 11.267 -3.111 23.167 1.00 23.33 ? 384 ARG B N 1 ATOM 6184 C CA . ARG B 1 384 ? 12.346 -4.082 23.085 1.00 22.39 ? 384 ARG B CA 1 ATOM 6185 C C . ARG B 1 384 ? 12.807 -4.440 24.486 1.00 19.74 ? 384 ARG B C 1 ATOM 6186 O O . ARG B 1 384 ? 12.627 -3.675 25.432 1.00 21.29 ? 384 ARG B O 1 ATOM 6187 C CB . ARG B 1 384 ? 13.523 -3.527 22.278 1.00 26.41 ? 384 ARG B CB 1 ATOM 6188 C CG . ARG B 1 384 ? 13.091 -2.904 20.956 1.00 31.35 ? 384 ARG B CG 1 ATOM 6189 C CD . ARG B 1 384 ? 14.202 -2.909 19.926 1.00 42.05 ? 384 ARG B CD 1 ATOM 6190 N NE . ARG B 1 384 ? 13.632 -2.978 18.581 1.00 47.48 ? 384 ARG B NE 1 ATOM 6191 C CZ . ARG B 1 384 ? 13.625 -4.075 17.833 1.00 43.65 ? 384 ARG B CZ 1 ATOM 6192 N NH1 . ARG B 1 384 ? 14.180 -5.192 18.286 1.00 37.07 ? 384 ARG B NH1 1 ATOM 6193 N NH2 . ARG B 1 384 ? 13.073 -4.051 16.626 1.00 45.68 ? 384 ARG B NH2 1 ATOM 6194 N N A SER B 1 385 ? 13.410 -5.628 24.597 0.50 23.22 ? 385 SER B N 1 ATOM 6195 N N B SER B 1 385 ? 13.425 -5.616 24.611 0.50 23.25 ? 385 SER B N 1 ATOM 6196 C CA A SER B 1 385 ? 13.905 -6.096 25.886 0.50 24.94 ? 385 SER B CA 1 ATOM 6197 C CA B SER B 1 385 ? 13.861 -6.062 25.930 0.50 24.95 ? 385 SER B CA 1 ATOM 6198 C C A SER B 1 385 ? 14.790 -5.054 26.553 0.50 23.78 ? 385 SER B C 1 ATOM 6199 C C B SER B 1 385 ? 14.836 -5.085 26.572 0.50 23.80 ? 385 SER B C 1 ATOM 6200 O O A SER B 1 385 ? 14.714 -4.854 27.772 0.50 22.76 ? 385 SER B O 1 ATOM 6201 O O B SER B 1 385 ? 14.863 -4.965 27.803 0.50 22.82 ? 385 SER B O 1 ATOM 6202 C CB A SER B 1 385 ? 14.668 -7.408 25.709 0.50 22.52 ? 385 SER B CB 1 ATOM 6203 C CB B SER B 1 385 ? 14.470 -7.456 25.831 0.50 22.71 ? 385 SER B CB 1 ATOM 6204 O OG A SER B 1 385 ? 15.038 -7.932 26.966 0.50 28.05 ? 385 SER B OG 1 ATOM 6205 O OG B SER B 1 385 ? 13.450 -8.380 25.506 0.50 23.28 ? 385 SER B OG 1 ATOM 6206 N N . VAL B 1 386 ? 15.628 -4.369 25.767 1.00 23.06 ? 386 VAL B N 1 ATOM 6207 C CA . VAL B 1 386 ? 16.535 -3.363 26.311 1.00 22.58 ? 386 VAL B CA 1 ATOM 6208 C C . VAL B 1 386 ? 15.812 -2.165 26.902 1.00 22.22 ? 386 VAL B C 1 ATOM 6209 O O . VAL B 1 386 ? 16.429 -1.402 27.652 1.00 22.50 ? 386 VAL B O 1 ATOM 6210 C CB . VAL B 1 386 ? 17.559 -2.856 25.266 1.00 24.51 ? 386 VAL B CB 1 ATOM 6211 C CG1 . VAL B 1 386 ? 18.590 -3.946 24.923 1.00 25.76 ? 386 VAL B CG1 1 ATOM 6212 C CG2 . VAL B 1 386 ? 16.852 -2.298 23.990 1.00 23.53 ? 386 VAL B CG2 1 ATOM 6213 N N . ASP B 1 387 ? 14.520 -1.976 26.605 1.00 24.07 ? 387 ASP B N 1 ATOM 6214 C CA . ASP B 1 387 ? 13.800 -0.793 27.070 1.00 20.95 ? 387 ASP B CA 1 ATOM 6215 C C . ASP B 1 387 ? 13.257 -0.920 28.494 1.00 25.72 ? 387 ASP B C 1 ATOM 6216 O O . ASP B 1 387 ? 12.875 0.097 29.091 1.00 24.06 ? 387 ASP B O 1 ATOM 6217 C CB . ASP B 1 387 ? 12.612 -0.484 26.141 1.00 25.13 ? 387 ASP B CB 1 ATOM 6218 C CG . ASP B 1 387 ? 13.027 -0.217 24.696 1.00 25.71 ? 387 ASP B CG 1 ATOM 6219 O OD1 . ASP B 1 387 ? 14.144 0.288 24.455 1.00 29.72 ? 387 ASP B OD1 1 ATOM 6220 O OD2 . ASP B 1 387 ? 12.221 -0.531 23.793 1.00 28.25 ? 387 ASP B OD2 1 ATOM 6221 N N . VAL B 1 388 ? 13.205 -2.133 29.049 1.00 21.01 ? 388 VAL B N 1 ATOM 6222 C CA . VAL B 1 388 ? 12.524 -2.355 30.326 1.00 22.03 ? 388 VAL B CA 1 ATOM 6223 C C . VAL B 1 388 ? 13.292 -1.721 31.478 1.00 22.16 ? 388 VAL B C 1 ATOM 6224 O O . VAL B 1 388 ? 12.704 -1.199 32.435 1.00 21.18 ? 388 VAL B O 1 ATOM 6225 C CB . VAL B 1 388 ? 12.322 -3.868 30.534 1.00 23.26 ? 388 VAL B CB 1 ATOM 6226 C CG1 . VAL B 1 388 ? 11.770 -4.176 31.934 1.00 23.49 ? 388 VAL B CG1 1 ATOM 6227 C CG2 . VAL B 1 388 ? 11.423 -4.422 29.427 1.00 24.97 ? 388 VAL B CG2 1 ATOM 6228 N N . TYR B 1 389 ? 14.620 -1.756 31.399 1.00 22.28 ? 389 TYR B N 1 ATOM 6229 C CA . TYR B 1 389 ? 15.481 -1.341 32.498 1.00 21.06 ? 389 TYR B CA 1 ATOM 6230 C C . TYR B 1 389 ? 15.197 0.086 32.942 1.00 22.89 ? 389 TYR B C 1 ATOM 6231 O O . TYR B 1 389 ? 15.072 0.352 34.142 1.00 22.48 ? 389 TYR B O 1 ATOM 6232 C CB . TYR B 1 389 ? 16.930 -1.521 32.055 1.00 22.19 ? 389 TYR B CB 1 ATOM 6233 C CG . TYR B 1 389 ? 18.024 -1.015 32.970 1.00 20.34 ? 389 TYR B CG 1 ATOM 6234 C CD1 . TYR B 1 389 ? 18.539 -1.816 33.991 1.00 23.25 ? 389 TYR B CD1 1 ATOM 6235 C CD2 . TYR B 1 389 ? 18.588 0.232 32.763 1.00 25.02 ? 389 TYR B CD2 1 ATOM 6236 C CE1 . TYR B 1 389 ? 19.571 -1.358 34.807 1.00 20.19 ? 389 TYR B CE1 1 ATOM 6237 C CE2 . TYR B 1 389 ? 19.606 0.704 33.568 1.00 26.07 ? 389 TYR B CE2 1 ATOM 6238 C CZ . TYR B 1 389 ? 20.100 -0.099 34.584 1.00 29.26 ? 389 TYR B CZ 1 ATOM 6239 O OH . TYR B 1 389 ? 21.116 0.373 35.372 1.00 28.28 ? 389 TYR B OH 1 ATOM 6240 N N . ASN B 1 390 ? 15.056 1.017 31.988 1.00 22.36 ? 390 ASN B N 1 ATOM 6241 C CA . ASN B 1 390 ? 14.788 2.409 32.354 1.00 21.87 ? 390 ASN B CA 1 ATOM 6242 C C . ASN B 1 390 ? 13.480 2.534 33.115 1.00 24.75 ? 390 ASN B C 1 ATOM 6243 O O . ASN B 1 390 ? 13.362 3.362 34.024 1.00 24.74 ? 390 ASN B O 1 ATOM 6244 C CB . ASN B 1 390 ? 14.732 3.310 31.108 1.00 25.81 ? 390 ASN B CB 1 ATOM 6245 C CG . ASN B 1 390 ? 16.109 3.600 30.509 1.00 31.49 ? 390 ASN B CG 1 ATOM 6246 O OD1 . ASN B 1 390 ? 17.105 3.715 31.228 1.00 29.32 ? 390 ASN B OD1 1 ATOM 6247 N ND2 . ASN B 1 390 ? 16.166 3.720 29.180 1.00 25.40 ? 390 ASN B ND2 1 ATOM 6248 N N . ILE B 1 391 ? 12.467 1.753 32.720 1.00 24.00 ? 391 ILE B N 1 ATOM 6249 C CA . ILE B 1 391 ? 11.177 1.769 33.412 1.00 23.91 ? 391 ILE B CA 1 ATOM 6250 C C . ILE B 1 391 ? 11.345 1.328 34.863 1.00 25.03 ? 391 ILE B C 1 ATOM 6251 O O . ILE B 1 391 ? 10.865 1.979 35.798 1.00 23.18 ? 391 ILE B O 1 ATOM 6252 C CB . ILE B 1 391 ? 10.168 0.862 32.681 1.00 21.17 ? 391 ILE B CB 1 ATOM 6253 C CG1 . ILE B 1 391 ? 10.054 1.230 31.197 1.00 27.91 ? 391 ILE B CG1 1 ATOM 6254 C CG2 . ILE B 1 391 ? 8.824 0.896 33.391 1.00 25.73 ? 391 ILE B CG2 1 ATOM 6255 C CD1 . ILE B 1 391 ? 9.264 0.211 30.363 1.00 25.93 ? 391 ILE B CD1 1 ATOM 6256 N N . MET B 1 392 ? 12.002 0.186 35.067 1.00 21.78 ? 392 MET B N 1 ATOM 6257 C CA . MET B 1 392 ? 12.184 -0.320 36.420 1.00 23.34 ? 392 MET B CA 1 ATOM 6258 C C . MET B 1 392 ? 12.969 0.667 37.270 1.00 22.75 ? 392 MET B C 1 ATOM 6259 O O . MET B 1 392 ? 12.577 0.978 38.398 1.00 21.90 ? 392 MET B O 1 ATOM 6260 C CB . MET B 1 392 ? 12.888 -1.677 36.378 1.00 19.60 ? 392 MET B CB 1 ATOM 6261 C CG . MET B 1 392 ? 12.049 -2.773 35.734 1.00 18.01 ? 392 MET B CG 1 ATOM 6262 S SD . MET B 1 392 ? 12.853 -4.396 35.987 1.00 21.12 ? 392 MET B SD 1 ATOM 6263 C CE . MET B 1 392 ? 14.349 -4.203 35.014 1.00 22.77 ? 392 MET B CE 1 ATOM 6264 N N . ALA B 1 393 ? 14.072 1.189 36.731 1.00 23.03 ? 393 ALA B N 1 ATOM 6265 C CA . ALA B 1 393 ? 14.888 2.118 37.503 1.00 24.14 ? 393 ALA B CA 1 ATOM 6266 C C . ALA B 1 393 ? 14.097 3.370 37.844 1.00 29.72 ? 393 ALA B C 1 ATOM 6267 O O . ALA B 1 393 ? 14.178 3.882 38.967 1.00 27.95 ? 393 ALA B O 1 ATOM 6268 C CB . ALA B 1 393 ? 16.155 2.466 36.722 1.00 24.27 ? 393 ALA B CB 1 ATOM 6269 N N . HIS B 1 394 ? 13.304 3.855 36.888 1.00 25.30 ? 394 HIS B N 1 ATOM 6270 C CA . HIS B 1 394 ? 12.499 5.048 37.112 1.00 29.74 ? 394 HIS B CA 1 ATOM 6271 C C . HIS B 1 394 ? 11.536 4.846 38.278 1.00 30.34 ? 394 HIS B C 1 ATOM 6272 O O . HIS B 1 394 ? 11.549 5.616 39.245 1.00 26.80 ? 394 HIS B O 1 ATOM 6273 C CB . HIS B 1 394 ? 11.747 5.421 35.835 1.00 29.47 ? 394 HIS B CB 1 ATOM 6274 C CG . HIS B 1 394 ? 10.926 6.669 35.965 1.00 31.46 ? 394 HIS B CG 1 ATOM 6275 N ND1 . HIS B 1 394 ? 11.472 7.933 35.888 1.00 40.56 ? 394 HIS B ND1 1 ATOM 6276 C CD2 . HIS B 1 394 ? 9.600 6.845 36.180 1.00 35.01 ? 394 HIS B CD2 1 ATOM 6277 C CE1 . HIS B 1 394 ? 10.518 8.833 36.042 1.00 37.24 ? 394 HIS B CE1 1 ATOM 6278 N NE2 . HIS B 1 394 ? 9.372 8.200 36.222 1.00 37.81 ? 394 HIS B NE2 1 ATOM 6279 N N . VAL B 1 395 ? 10.715 3.789 38.232 1.00 24.40 ? 395 VAL B N 1 ATOM 6280 C CA . VAL B 1 395 ? 9.728 3.628 39.297 1.00 27.86 ? 395 VAL B CA 1 ATOM 6281 C C . VAL B 1 395 ? 10.353 3.125 40.593 1.00 26.41 ? 395 VAL B C 1 ATOM 6282 O O . VAL B 1 395 ? 9.720 3.228 41.656 1.00 27.35 ? 395 VAL B O 1 ATOM 6283 C CB . VAL B 1 395 ? 8.560 2.706 38.892 1.00 25.23 ? 395 VAL B CB 1 ATOM 6284 C CG1 . VAL B 1 395 ? 7.775 3.298 37.716 1.00 24.83 ? 395 VAL B CG1 1 ATOM 6285 C CG2 . VAL B 1 395 ? 9.036 1.267 38.596 1.00 20.98 ? 395 VAL B CG2 1 ATOM 6286 N N . ALA B 1 396 ? 11.566 2.565 40.540 1.00 26.18 ? 396 ALA B N 1 ATOM 6287 C CA . ALA B 1 396 ? 12.282 2.226 41.765 1.00 27.10 ? 396 ALA B CA 1 ATOM 6288 C C . ALA B 1 396 ? 12.989 3.425 42.378 1.00 30.73 ? 396 ALA B C 1 ATOM 6289 O O . ALA B 1 396 ? 13.518 3.307 43.486 1.00 32.56 ? 396 ALA B O 1 ATOM 6290 C CB . ALA B 1 396 ? 13.321 1.134 41.507 1.00 24.34 ? 396 ALA B CB 1 ATOM 6291 N N . GLY B 1 397 ? 13.015 4.563 41.689 1.00 29.78 ? 397 GLY B N 1 ATOM 6292 C CA . GLY B 1 397 ? 13.694 5.737 42.204 1.00 32.33 ? 397 GLY B CA 1 ATOM 6293 C C . GLY B 1 397 ? 15.202 5.616 42.214 1.00 38.70 ? 397 GLY B C 1 ATOM 6294 O O . GLY B 1 397 ? 15.848 5.945 43.216 1.00 42.89 ? 397 GLY B O 1 ATOM 6295 N N . ILE B 1 398 ? 15.789 5.154 41.113 1.00 30.30 ? 398 ILE B N 1 ATOM 6296 C CA . ILE B 1 398 ? 17.237 5.046 41.017 1.00 32.20 ? 398 ILE B CA 1 ATOM 6297 C C . ILE B 1 398 ? 17.666 5.464 39.622 1.00 35.17 ? 398 ILE B C 1 ATOM 6298 O O . ILE B 1 398 ? 16.991 5.160 38.632 1.00 33.03 ? 398 ILE B O 1 ATOM 6299 C CB . ILE B 1 398 ? 17.723 3.622 41.374 1.00 37.16 ? 398 ILE B CB 1 ATOM 6300 C CG1 . ILE B 1 398 ? 19.233 3.608 41.599 1.00 33.79 ? 398 ILE B CG1 1 ATOM 6301 C CG2 . ILE B 1 398 ? 17.341 2.615 40.303 1.00 30.18 ? 398 ILE B CG2 1 ATOM 6302 C CD1 . ILE B 1 398 ? 19.700 2.405 42.389 1.00 32.68 ? 398 ILE B CD1 1 ATOM 6303 N N . THR B 1 399 ? 18.768 6.202 39.548 1.00 31.14 ? 399 THR B N 1 ATOM 6304 C CA . THR B 1 399 ? 19.297 6.648 38.264 1.00 32.54 ? 399 THR B CA 1 ATOM 6305 C C . THR B 1 399 ? 19.791 5.450 37.466 1.00 30.66 ? 399 THR B C 1 ATOM 6306 O O . THR B 1 399 ? 20.682 4.737 37.936 1.00 34.78 ? 399 THR B O 1 ATOM 6307 C CB . THR B 1 399 ? 20.440 7.641 38.466 1.00 37.08 ? 399 THR B CB 1 ATOM 6308 O OG1 . THR B 1 399 ? 19.975 8.750 39.241 1.00 37.06 ? 399 THR B OG1 1 ATOM 6309 C CG2 . THR B 1 399 ? 20.947 8.138 37.122 1.00 35.60 ? 399 THR B CG2 1 ATOM 6310 N N . PRO B 1 400 ? 19.253 5.189 36.275 1.00 31.84 ? 400 PRO B N 1 ATOM 6311 C CA . PRO B 1 400 ? 19.752 4.061 35.476 1.00 30.21 ? 400 PRO B CA 1 ATOM 6312 C C . PRO B 1 400 ? 21.193 4.282 35.026 1.00 38.34 ? 400 PRO B C 1 ATOM 6313 O O . PRO B 1 400 ? 21.603 5.399 34.707 1.00 33.32 ? 400 PRO B O 1 ATOM 6314 C CB . PRO B 1 400 ? 18.794 4.022 34.280 1.00 33.34 ? 400 PRO B CB 1 ATOM 6315 C CG . PRO B 1 400 ? 18.217 5.414 34.200 1.00 31.83 ? 400 PRO B CG 1 ATOM 6316 C CD . PRO B 1 400 ? 18.177 5.934 35.601 1.00 30.53 ? 400 PRO B CD 1 ATOM 6317 N N . LEU B 1 401 ? 21.967 3.201 35.012 1.00 32.73 ? 401 LEU B N 1 ATOM 6318 C CA . LEU B 1 401 ? 23.259 3.246 34.351 1.00 32.40 ? 401 LEU B CA 1 ATOM 6319 C C . LEU B 1 401 ? 23.047 3.377 32.841 1.00 37.33 ? 401 LEU B C 1 ATOM 6320 O O . LEU B 1 401 ? 22.003 2.975 32.323 1.00 33.91 ? 401 LEU B O 1 ATOM 6321 C CB . LEU B 1 401 ? 24.074 1.990 34.662 1.00 31.92 ? 401 LEU B CB 1 ATOM 6322 C CG . LEU B 1 401 ? 24.332 1.693 36.142 1.00 33.14 ? 401 LEU B CG 1 ATOM 6323 C CD1 . LEU B 1 401 ? 25.321 0.531 36.344 1.00 33.30 ? 401 LEU B CD1 1 ATOM 6324 C CD2 . LEU B 1 401 ? 24.814 2.945 36.848 1.00 38.91 ? 401 LEU B CD2 1 ATOM 6325 N N . PRO B 1 402 ? 24.010 3.957 32.122 1.00 38.83 ? 402 PRO B N 1 ATOM 6326 C CA . PRO B 1 402 ? 23.874 4.108 30.665 1.00 34.24 ? 402 PRO B CA 1 ATOM 6327 C C . PRO B 1 402 ? 23.572 2.785 29.975 1.00 33.40 ? 402 PRO B C 1 ATOM 6328 O O . PRO B 1 402 ? 24.243 1.778 30.209 1.00 31.69 ? 402 PRO B O 1 ATOM 6329 C CB . PRO B 1 402 ? 25.244 4.654 30.244 1.00 37.06 ? 402 PRO B CB 1 ATOM 6330 C CG . PRO B 1 402 ? 25.730 5.394 31.443 1.00 41.14 ? 402 PRO B CG 1 ATOM 6331 C CD . PRO B 1 402 ? 25.209 4.642 32.643 1.00 40.80 ? 402 PRO B CD 1 ATOM 6332 N N . ASN B 1 403 ? 22.562 2.791 29.104 1.00 29.06 ? 403 ASN B N 1 ATOM 6333 C CA . ASN B 1 403 ? 22.082 1.546 28.513 1.00 34.68 ? 403 ASN B CA 1 ATOM 6334 C C . ASN B 1 403 ? 21.571 1.812 27.097 1.00 33.73 ? 403 ASN B C 1 ATOM 6335 O O . ASN B 1 403 ? 21.641 2.933 26.588 1.00 36.28 ? 403 ASN B O 1 ATOM 6336 C CB . ASN B 1 403 ? 21.015 0.915 29.418 1.00 30.09 ? 403 ASN B CB 1 ATOM 6337 C CG . ASN B 1 403 ? 19.742 1.744 29.496 1.00 34.70 ? 403 ASN B CG 1 ATOM 6338 O OD1 . ASN B 1 403 ? 18.818 1.545 28.701 1.00 29.46 ? 403 ASN B OD1 1 ATOM 6339 N ND2 . ASN B 1 403 ? 19.674 2.663 30.470 1.00 28.63 ? 403 ASN B ND2 1 ATOM 6340 N N . ASN B 1 404 ? 21.070 0.758 26.452 1.00 30.24 ? 404 ASN B N 1 ATOM 6341 C CA . ASN B 1 404 ? 20.637 0.809 25.064 1.00 29.18 ? 404 ASN B CA 1 ATOM 6342 C C . ASN B 1 404 ? 19.128 0.927 24.921 1.00 30.11 ? 404 ASN B C 1 ATOM 6343 O O . ASN B 1 404 ? 18.623 0.895 23.796 1.00 32.71 ? 404 ASN B O 1 ATOM 6344 C CB . ASN B 1 404 ? 21.137 -0.428 24.314 1.00 35.58 ? 404 ASN B CB 1 ATOM 6345 C CG . ASN B 1 404 ? 22.621 -0.657 24.506 1.00 36.16 ? 404 ASN B CG 1 ATOM 6346 O OD1 . ASN B 1 404 ? 23.056 -1.751 24.877 1.00 29.63 ? 404 ASN B OD1 1 ATOM 6347 N ND2 . ASN B 1 404 ? 23.415 0.381 24.256 1.00 37.26 ? 404 ASN B ND2 1 ATOM 6348 N N . GLY B 1 405 ? 18.398 1.058 26.025 1.00 27.28 ? 405 GLY B N 1 ATOM 6349 C CA . GLY B 1 405 ? 16.967 1.263 25.933 1.00 26.55 ? 405 GLY B CA 1 ATOM 6350 C C . GLY B 1 405 ? 16.633 2.625 25.355 1.00 33.23 ? 405 GLY B C 1 ATOM 6351 O O . GLY B 1 405 ? 17.413 3.577 25.436 1.00 32.07 ? 405 GLY B O 1 ATOM 6352 N N . SER B 1 406 ? 15.452 2.714 24.757 1.00 32.81 ? 406 SER B N 1 ATOM 6353 C CA . SER B 1 406 ? 14.934 3.976 24.242 1.00 33.21 ? 406 SER B CA 1 ATOM 6354 C C . SER B 1 406 ? 13.876 4.486 25.213 1.00 31.24 ? 406 SER B C 1 ATOM 6355 O O . SER B 1 406 ? 12.803 3.889 25.345 1.00 27.89 ? 406 SER B O 1 ATOM 6356 C CB . SER B 1 406 ? 14.365 3.796 22.837 1.00 35.13 ? 406 SER B CB 1 ATOM 6357 O OG . SER B 1 406 ? 13.566 4.907 22.463 1.00 32.27 ? 406 SER B OG 1 ATOM 6358 N N . TRP B 1 407 ? 14.186 5.578 25.912 1.00 27.70 ? 407 TRP B N 1 ATOM 6359 C CA . TRP B 1 407 ? 13.183 6.200 26.764 1.00 26.48 ? 407 TRP B CA 1 ATOM 6360 C C . TRP B 1 407 ? 11.976 6.649 25.950 1.00 30.77 ? 407 TRP B C 1 ATOM 6361 O O . TRP B 1 407 ? 10.828 6.541 26.402 1.00 31.31 ? 407 TRP B O 1 ATOM 6362 C CB . TRP B 1 407 ? 13.803 7.382 27.506 1.00 26.49 ? 407 TRP B CB 1 ATOM 6363 C CG . TRP B 1 407 ? 12.938 7.975 28.565 1.00 29.30 ? 407 TRP B CG 1 ATOM 6364 C CD1 . TRP B 1 407 ? 12.463 9.256 28.617 1.00 36.43 ? 407 TRP B CD1 1 ATOM 6365 C CD2 . TRP B 1 407 ? 12.469 7.327 29.753 1.00 39.18 ? 407 TRP B CD2 1 ATOM 6366 N NE1 . TRP B 1 407 ? 11.718 9.440 29.761 1.00 34.69 ? 407 TRP B NE1 1 ATOM 6367 C CE2 . TRP B 1 407 ? 11.712 8.271 30.476 1.00 38.43 ? 407 TRP B CE2 1 ATOM 6368 C CE3 . TRP B 1 407 ? 12.617 6.039 30.276 1.00 32.99 ? 407 TRP B CE3 1 ATOM 6369 C CZ2 . TRP B 1 407 ? 11.094 7.962 31.689 1.00 40.54 ? 407 TRP B CZ2 1 ATOM 6370 C CZ3 . TRP B 1 407 ? 12.008 5.739 31.485 1.00 31.91 ? 407 TRP B CZ3 1 ATOM 6371 C CH2 . TRP B 1 407 ? 11.261 6.692 32.177 1.00 32.54 ? 407 TRP B CH2 1 ATOM 6372 N N . SER B 1 408 ? 12.213 7.134 24.734 1.00 29.56 ? 408 SER B N 1 ATOM 6373 C CA . SER B 1 408 ? 11.103 7.608 23.916 1.00 30.09 ? 408 SER B CA 1 ATOM 6374 C C . SER B 1 408 ? 10.132 6.479 23.586 1.00 30.14 ? 408 SER B C 1 ATOM 6375 O O . SER B 1 408 ? 8.932 6.723 23.419 1.00 29.59 ? 408 SER B O 1 ATOM 6376 C CB . SER B 1 408 ? 11.639 8.264 22.643 1.00 34.15 ? 408 SER B CB 1 ATOM 6377 O OG . SER B 1 408 ? 12.565 7.420 21.971 1.00 32.10 ? 408 SER B OG 1 ATOM 6378 N N . ARG B 1 409 ? 10.618 5.234 23.539 1.00 31.15 ? 409 ARG B N 1 ATOM 6379 C CA . ARG B 1 409 ? 9.752 4.103 23.229 1.00 30.07 ? 409 ARG B CA 1 ATOM 6380 C C . ARG B 1 409 ? 8.815 3.708 24.373 1.00 36.16 ? 409 ARG B C 1 ATOM 6381 O O . ARG B 1 409 ? 7.842 2.988 24.114 1.00 30.64 ? 409 ARG B O 1 ATOM 6382 C CB . ARG B 1 409 ? 10.594 2.884 22.813 1.00 28.16 ? 409 ARG B CB 1 ATOM 6383 C CG . ARG B 1 409 ? 11.097 2.916 21.358 1.00 30.90 ? 409 ARG B CG 1 ATOM 6384 C CD . ARG B 1 409 ? 11.457 1.508 20.828 1.00 30.56 ? 409 ARG B CD 1 ATOM 6385 N NE . ARG B 1 409 ? 12.610 0.941 21.534 1.00 29.23 ? 409 ARG B NE 1 ATOM 6386 C CZ . ARG B 1 409 ? 13.842 0.898 21.043 1.00 30.79 ? 409 ARG B CZ 1 ATOM 6387 N NH1 . ARG B 1 409 ? 14.092 1.360 19.822 1.00 38.42 ? 409 ARG B NH1 1 ATOM 6388 N NH2 . ARG B 1 409 ? 14.830 0.393 21.768 1.00 33.11 ? 409 ARG B NH2 1 ATOM 6389 N N . VAL B 1 410 ? 9.048 4.169 25.610 1.00 26.69 ? 410 VAL B N 1 ATOM 6390 C CA . VAL B 1 410 ? 8.298 3.648 26.756 1.00 24.83 ? 410 VAL B CA 1 ATOM 6391 C C . VAL B 1 410 ? 7.650 4.723 27.625 1.00 31.84 ? 410 VAL B C 1 ATOM 6392 O O . VAL B 1 410 ? 6.740 4.419 28.402 1.00 32.82 ? 410 VAL B O 1 ATOM 6393 C CB . VAL B 1 410 ? 9.189 2.755 27.658 1.00 32.50 ? 410 VAL B CB 1 ATOM 6394 C CG1 . VAL B 1 410 ? 9.950 1.725 26.842 1.00 28.54 ? 410 VAL B CG1 1 ATOM 6395 C CG2 . VAL B 1 410 ? 10.138 3.597 28.504 1.00 33.42 ? 410 VAL B CG2 1 ATOM 6396 N N . VAL B 1 411 ? 8.096 5.978 27.516 1.00 34.73 ? 411 VAL B N 1 ATOM 6397 C CA . VAL B 1 411 ? 7.697 7.011 28.484 1.00 32.79 ? 411 VAL B CA 1 ATOM 6398 C C . VAL B 1 411 ? 6.185 7.246 28.530 1.00 28.18 ? 411 VAL B C 1 ATOM 6399 O O . VAL B 1 411 ? 5.658 7.662 29.567 1.00 26.73 ? 411 VAL B O 1 ATOM 6400 C CB . VAL B 1 411 ? 8.446 8.337 28.189 1.00 36.22 ? 411 VAL B CB 1 ATOM 6401 C CG1 . VAL B 1 411 ? 8.029 8.910 26.837 1.00 36.32 ? 411 VAL B CG1 1 ATOM 6402 C CG2 . VAL B 1 411 ? 8.226 9.353 29.316 1.00 36.39 ? 411 VAL B CG2 1 ATOM 6403 N N A SER B 1 412 ? 5.465 6.961 27.443 0.50 33.00 ? 412 SER B N 1 ATOM 6404 N N B SER B 1 412 ? 5.478 6.961 27.436 0.50 33.00 ? 412 SER B N 1 ATOM 6405 C CA A SER B 1 412 ? 4.037 7.268 27.415 0.50 32.34 ? 412 SER B CA 1 ATOM 6406 C CA B SER B 1 412 ? 4.044 7.226 27.377 0.50 32.35 ? 412 SER B CA 1 ATOM 6407 C C A SER B 1 412 ? 3.200 6.322 28.274 0.50 31.61 ? 412 SER B C 1 ATOM 6408 C C B SER B 1 412 ? 3.260 6.381 28.378 0.50 31.60 ? 412 SER B C 1 ATOM 6409 O O A SER B 1 412 ? 2.038 6.637 28.551 0.50 30.30 ? 412 SER B O 1 ATOM 6410 O O B SER B 1 412 ? 2.215 6.819 28.871 0.50 29.22 ? 412 SER B O 1 ATOM 6411 C CB A SER B 1 412 ? 3.523 7.272 25.967 0.50 34.84 ? 412 SER B CB 1 ATOM 6412 C CB B SER B 1 412 ? 3.541 6.985 25.952 0.50 35.00 ? 412 SER B CB 1 ATOM 6413 O OG A SER B 1 412 ? 3.621 5.996 25.352 0.50 31.87 ? 412 SER B OG 1 ATOM 6414 O OG B SER B 1 412 ? 2.162 7.274 25.836 0.50 38.78 ? 412 SER B OG 1 ATOM 6415 N N . MET B 1 413 ? 3.746 5.181 28.708 1.00 29.51 ? 413 MET B N 1 ATOM 6416 C CA . MET B 1 413 ? 2.988 4.309 29.601 1.00 27.64 ? 413 MET B CA 1 ATOM 6417 C C . MET B 1 413 ? 2.959 4.818 31.038 1.00 24.00 ? 413 MET B C 1 ATOM 6418 O O . MET B 1 413 ? 2.168 4.320 31.844 1.00 29.42 ? 413 MET B O 1 ATOM 6419 C CB . MET B 1 413 ? 3.553 2.880 29.567 1.00 26.15 ? 413 MET B CB 1 ATOM 6420 C CG . MET B 1 413 ? 4.872 2.757 30.244 1.00 28.83 ? 413 MET B CG 1 ATOM 6421 S SD . MET B 1 413 ? 5.412 1.037 30.327 1.00 26.54 ? 413 MET B SD 1 ATOM 6422 C CE . MET B 1 413 ? 5.775 0.717 28.600 1.00 25.17 ? 413 MET B CE 1 ATOM 6423 N N . LEU B 1 414 ? 3.771 5.811 31.378 1.00 30.06 ? 414 LEU B N 1 ATOM 6424 C CA . LEU B 1 414 ? 3.874 6.281 32.756 1.00 26.68 ? 414 LEU B CA 1 ATOM 6425 C C . LEU B 1 414 ? 2.844 7.363 33.043 1.00 39.39 ? 414 LEU B C 1 ATOM 6426 O O . LEU B 1 414 ? 2.572 8.215 32.194 1.00 32.67 ? 414 LEU B O 1 ATOM 6427 C CB . LEU B 1 414 ? 5.277 6.817 33.024 1.00 32.21 ? 414 LEU B CB 1 ATOM 6428 C CG . LEU B 1 414 ? 6.374 5.765 32.885 1.00 37.52 ? 414 LEU B CG 1 ATOM 6429 C CD1 . LEU B 1 414 ? 7.724 6.436 32.789 1.00 39.06 ? 414 LEU B CD1 1 ATOM 6430 C CD2 . LEU B 1 414 ? 6.312 4.811 34.066 1.00 34.98 ? 414 LEU B CD2 1 ATOM 6431 N N . LYS B 1 415 ? 2.291 7.338 34.254 1.00 30.72 ? 415 LYS B N 1 ATOM 6432 C CA . LYS B 1 415 ? 1.160 8.191 34.604 1.00 41.29 ? 415 LYS B CA 1 ATOM 6433 C C . LYS B 1 415 ? 1.545 9.663 34.792 1.00 49.21 ? 415 LYS B C 1 ATOM 6434 O O . LYS B 1 415 ? 2.654 9.982 35.226 1.00 50.97 ? 415 LYS B O 1 ATOM 6435 C CB . LYS B 1 415 ? 0.492 7.662 35.871 1.00 35.23 ? 415 LYS B CB 1 ATOM 6436 C CG . LYS B 1 415 ? -0.928 8.129 36.074 1.00 46.29 ? 415 LYS B CG 1 ATOM 6437 C CD . LYS B 1 415 ? -1.691 7.162 36.974 1.00 47.54 ? 415 LYS B CD 1 ATOM 6438 C CE . LYS B 1 415 ? -3.133 7.609 37.190 1.00 51.22 ? 415 LYS B CE 1 ATOM 6439 N NZ . LYS B 1 415 ? -3.873 6.679 38.094 1.00 58.21 ? 415 LYS B NZ 1 HETATM 6440 C C1 . NAG C 2 . ? -21.512 3.727 -2.385 1.00 31.73 ? 501 NAG A C1 1 HETATM 6441 C C2 . NAG C 2 . ? -22.882 4.392 -2.266 1.00 35.66 ? 501 NAG A C2 1 HETATM 6442 C C3 . NAG C 2 . ? -23.967 3.328 -2.180 1.00 42.20 ? 501 NAG A C3 1 HETATM 6443 C C4 . NAG C 2 . ? -23.877 2.362 -3.354 1.00 42.46 ? 501 NAG A C4 1 HETATM 6444 C C5 . NAG C 2 . ? -22.451 1.806 -3.487 1.00 35.77 ? 501 NAG A C5 1 HETATM 6445 C C6 . NAG C 2 . ? -22.217 1.023 -4.762 1.00 37.25 ? 501 NAG A C6 1 HETATM 6446 C C7 . NAG C 2 . ? -22.916 6.621 -1.250 1.00 38.13 ? 501 NAG A C7 1 HETATM 6447 C C8 . NAG C 2 . ? -23.032 7.408 0.020 1.00 41.37 ? 501 NAG A C8 1 HETATM 6448 N N2 . NAG C 2 . ? -22.957 5.290 -1.124 1.00 32.07 ? 501 NAG A N2 1 HETATM 6449 O O3 . NAG C 2 . ? -25.254 3.934 -2.142 1.00 45.45 ? 501 NAG A O3 1 HETATM 6450 O O4 . NAG C 2 . ? -24.791 1.309 -3.069 1.00 48.83 ? 501 NAG A O4 1 HETATM 6451 O O5 . NAG C 2 . ? -21.497 2.876 -3.510 1.00 29.77 ? 501 NAG A O5 1 HETATM 6452 O O6 . NAG C 2 . ? -22.701 1.724 -5.901 1.00 36.60 ? 501 NAG A O6 1 HETATM 6453 O O7 . NAG C 2 . ? -22.788 7.167 -2.345 1.00 40.42 ? 501 NAG A O7 1 HETATM 6454 C C1 . NAG D 2 . ? -25.390 0.703 -4.224 1.00 59.52 ? 502 NAG A C1 1 HETATM 6455 C C2 . NAG D 2 . ? -25.974 -0.648 -3.824 1.00 64.96 ? 502 NAG A C2 1 HETATM 6456 C C3 . NAG D 2 . ? -27.084 -1.035 -4.785 1.00 70.99 ? 502 NAG A C3 1 HETATM 6457 C C4 . NAG D 2 . ? -28.261 -0.086 -4.614 1.00 69.96 ? 502 NAG A C4 1 HETATM 6458 C C5 . NAG D 2 . ? -27.791 1.367 -4.520 1.00 71.87 ? 502 NAG A C5 1 HETATM 6459 C C6 . NAG D 2 . ? -27.948 1.978 -3.143 1.00 67.63 ? 502 NAG A C6 1 HETATM 6460 C C7 . NAG D 2 . ? -24.303 -2.038 -2.660 1.00 61.30 ? 502 NAG A C7 1 HETATM 6461 C C8 . NAG D 2 . ? -24.719 -1.335 -1.401 1.00 56.63 ? 502 NAG A C8 1 HETATM 6462 N N2 . NAG D 2 . ? -24.941 -1.673 -3.781 1.00 62.06 ? 502 NAG A N2 1 HETATM 6463 O O3 . NAG D 2 . ? -27.503 -2.369 -4.522 1.00 77.45 ? 502 NAG A O3 1 HETATM 6464 O O4 . NAG D 2 . ? -29.132 -0.213 -5.731 1.00 73.85 ? 502 NAG A O4 1 HETATM 6465 O O5 . NAG D 2 . ? -26.410 1.514 -4.902 1.00 67.82 ? 502 NAG A O5 1 HETATM 6466 O O6 . NAG D 2 . ? -29.165 1.575 -2.532 1.00 71.61 ? 502 NAG A O6 1 HETATM 6467 O O7 . NAG D 2 . ? -23.427 -2.900 -2.661 1.00 68.34 ? 502 NAG A O7 1 HETATM 6468 C C1 . NAG E 2 . ? 15.524 -10.797 -19.660 1.00 51.28 ? 503 NAG A C1 1 HETATM 6469 C C2 . NAG E 2 . ? 16.982 -10.724 -20.118 1.00 54.78 ? 503 NAG A C2 1 HETATM 6470 C C3 . NAG E 2 . ? 17.498 -12.098 -20.565 1.00 58.51 ? 503 NAG A C3 1 HETATM 6471 C C4 . NAG E 2 . ? 17.174 -13.184 -19.545 1.00 60.78 ? 503 NAG A C4 1 HETATM 6472 C C5 . NAG E 2 . ? 15.684 -13.142 -19.215 1.00 53.84 ? 503 NAG A C5 1 HETATM 6473 C C6 . NAG E 2 . ? 15.259 -14.124 -18.142 1.00 51.54 ? 503 NAG A C6 1 HETATM 6474 C C7 . NAG E 2 . ? 17.861 -8.660 -21.127 1.00 51.79 ? 503 NAG A C7 1 HETATM 6475 C C8 . NAG E 2 . ? 17.846 -7.774 -22.337 1.00 53.63 ? 503 NAG A C8 1 HETATM 6476 N N2 . NAG E 2 . ? 17.105 -9.760 -21.200 1.00 56.34 ? 503 NAG A N2 1 HETATM 6477 O O3 . NAG E 2 . ? 18.908 -12.021 -20.734 1.00 60.76 ? 503 NAG A O3 1 HETATM 6478 O O4 . NAG E 2 . ? 17.523 -14.452 -20.096 1.00 65.18 ? 503 NAG A O4 1 HETATM 6479 O O5 . NAG E 2 . ? 15.368 -11.836 -18.716 1.00 50.84 ? 503 NAG A O5 1 HETATM 6480 O O6 . NAG E 2 . ? 16.272 -14.268 -17.153 1.00 48.79 ? 503 NAG A O6 1 HETATM 6481 O O7 . NAG E 2 . ? 18.533 -8.397 -20.135 1.00 55.05 ? 503 NAG A O7 1 HETATM 6482 C C1 . NAG F 2 . ? 18.276 -15.310 -19.202 1.00 64.80 ? 504 NAG A C1 1 HETATM 6483 C C2 . NAG F 2 . ? 18.208 -16.753 -19.724 1.00 70.79 ? 504 NAG A C2 1 HETATM 6484 C C3 . NAG F 2 . ? 18.990 -17.701 -18.808 1.00 75.25 ? 504 NAG A C3 1 HETATM 6485 C C4 . NAG F 2 . ? 20.386 -17.163 -18.518 1.00 73.00 ? 504 NAG A C4 1 HETATM 6486 C C5 . NAG F 2 . ? 20.301 -15.722 -18.030 1.00 74.60 ? 504 NAG A C5 1 HETATM 6487 C C6 . NAG F 2 . ? 21.652 -15.089 -17.794 1.00 80.60 ? 504 NAG A C6 1 HETATM 6488 C C7 . NAG F 2 . ? 16.047 -16.909 -20.892 1.00 71.24 ? 504 NAG A C7 1 HETATM 6489 C C8 . NAG F 2 . ? 14.643 -17.434 -20.830 1.00 71.71 ? 504 NAG A C8 1 HETATM 6490 N N2 . NAG F 2 . ? 16.824 -17.189 -19.840 1.00 70.58 ? 504 NAG A N2 1 HETATM 6491 O O3 . NAG F 2 . ? 19.099 -18.974 -19.436 1.00 79.03 ? 504 NAG A O3 1 HETATM 6492 O O4 . NAG F 2 . ? 21.019 -17.963 -17.526 1.00 75.12 ? 504 NAG A O4 1 HETATM 6493 O O5 . NAG F 2 . ? 19.634 -14.928 -19.020 1.00 70.97 ? 504 NAG A O5 1 HETATM 6494 O O6 . NAG F 2 . ? 21.533 -13.696 -17.538 1.00 80.08 ? 504 NAG A O6 1 HETATM 6495 O O7 . NAG F 2 . ? 16.458 -16.263 -21.853 1.00 71.73 ? 504 NAG A O7 1 HETATM 6496 C C1 . FUL G 3 . ? 15.963 -13.846 -15.798 1.00 46.51 ? 505 FUL A C1 1 HETATM 6497 C C2 . FUL G 3 . ? 15.792 -12.342 -15.733 1.00 45.57 ? 505 FUL A C2 1 HETATM 6498 O O2 . FUL G 3 . ? 14.746 -11.869 -16.540 1.00 51.60 ? 505 FUL A O2 1 HETATM 6499 C C3 . FUL G 3 . ? 15.478 -11.866 -14.368 1.00 49.37 ? 505 FUL A C3 1 HETATM 6500 O O3 . FUL G 3 . ? 15.738 -10.456 -14.357 1.00 57.85 ? 505 FUL A O3 1 HETATM 6501 C C4 . FUL G 3 . ? 16.328 -12.484 -13.256 1.00 45.12 ? 505 FUL A C4 1 HETATM 6502 O O4 . FUL G 3 . ? 17.152 -11.492 -12.721 1.00 49.43 ? 505 FUL A O4 1 HETATM 6503 C C5 . FUL G 3 . ? 17.192 -13.736 -13.663 1.00 51.44 ? 505 FUL A C5 1 HETATM 6504 C C6 . FUL G 3 . ? 18.669 -13.468 -13.489 1.00 37.87 ? 505 FUL A C6 1 HETATM 6505 O O5 . FUL G 3 . ? 17.034 -14.259 -15.007 1.00 50.04 ? 505 FUL A O5 1 HETATM 6506 C C1 . NAG H 2 . ? -12.714 -0.990 13.778 1.00 28.65 ? 506 NAG A C1 1 HETATM 6507 C C2 . NAG H 2 . ? -13.440 -1.997 14.685 1.00 32.23 ? 506 NAG A C2 1 HETATM 6508 C C3 . NAG H 2 . ? -14.896 -2.172 14.242 1.00 36.28 ? 506 NAG A C3 1 HETATM 6509 C C4 . NAG H 2 . ? -15.592 -0.831 14.046 1.00 30.65 ? 506 NAG A C4 1 HETATM 6510 C C5 . NAG H 2 . ? -14.748 0.070 13.149 1.00 29.77 ? 506 NAG A C5 1 HETATM 6511 C C6 . NAG H 2 . ? -15.321 1.459 12.984 1.00 32.15 ? 506 NAG A C6 1 HETATM 6512 C C7 . NAG H 2 . ? -11.978 -3.721 15.668 1.00 33.56 ? 506 NAG A C7 1 HETATM 6513 C C8 . NAG H 2 . ? -11.347 -5.069 15.465 1.00 42.10 ? 506 NAG A C8 1 HETATM 6514 N N2 . NAG H 2 . ? -12.754 -3.282 14.671 1.00 29.16 ? 506 NAG A N2 1 HETATM 6515 O O3 . NAG H 2 . ? -15.585 -2.942 15.222 1.00 36.40 ? 506 NAG A O3 1 HETATM 6516 O O4 . NAG H 2 . ? -16.846 -1.052 13.410 1.00 34.29 ? 506 NAG A O4 1 HETATM 6517 O O5 . NAG H 2 . ? -13.446 0.222 13.727 1.00 32.11 ? 506 NAG A O5 1 HETATM 6518 O O6 . NAG H 2 . ? -15.333 2.151 14.224 1.00 38.11 ? 506 NAG A O6 1 HETATM 6519 O O7 . NAG H 2 . ? -11.797 -3.067 16.693 1.00 44.43 ? 506 NAG A O7 1 HETATM 6520 C C1 . NAG I 2 . ? -17.968 -0.529 14.148 1.00 45.93 ? 507 NAG A C1 1 HETATM 6521 C C2 . NAG I 2 . ? -19.136 -0.461 13.178 1.00 43.92 ? 507 NAG A C2 1 HETATM 6522 C C3 . NAG I 2 . ? -20.376 0.068 13.888 1.00 48.67 ? 507 NAG A C3 1 HETATM 6523 C C4 . NAG I 2 . ? -20.691 -0.806 15.093 1.00 56.94 ? 507 NAG A C4 1 HETATM 6524 C C5 . NAG I 2 . ? -19.473 -0.901 16.009 1.00 55.62 ? 507 NAG A C5 1 HETATM 6525 C C6 . NAG I 2 . ? -19.670 -1.886 17.138 1.00 59.16 ? 507 NAG A C6 1 HETATM 6526 C C7 . NAG I 2 . ? -18.497 -0.173 10.826 1.00 42.74 ? 507 NAG A C7 1 HETATM 6527 C C8 . NAG I 2 . ? -18.205 0.805 9.731 1.00 43.65 ? 507 NAG A C8 1 HETATM 6528 N N2 . NAG I 2 . ? -18.818 0.353 12.015 1.00 42.74 ? 507 NAG A N2 1 HETATM 6529 O O3 . NAG I 2 . ? -21.477 0.056 12.990 1.00 53.30 ? 507 NAG A O3 1 HETATM 6530 O O4 . NAG I 2 . ? -21.798 -0.273 15.811 1.00 65.53 ? 507 NAG A O4 1 HETATM 6531 O O5 . NAG I 2 . ? -18.322 -1.347 15.271 1.00 50.97 ? 507 NAG A O5 1 HETATM 6532 O O6 . NAG I 2 . ? -20.065 -3.159 16.645 1.00 63.02 ? 507 NAG A O6 1 HETATM 6533 O O7 . NAG I 2 . ? -18.433 -1.385 10.646 1.00 44.28 ? 507 NAG A O7 1 HETATM 6534 ZN ZN . ZN J 4 . ? 4.556 -4.188 -5.201 1.00 26.47 ? 508 ZN A ZN 1 HETATM 6535 ZN ZN . ZN K 4 . ? 2.767 -1.324 -2.822 1.00 27.15 ? 509 ZN A ZN 1 HETATM 6536 C C1 . EDO L 5 . ? -11.754 -11.099 12.799 1.00 26.28 ? 510 EDO A C1 1 HETATM 6537 O O1 . EDO L 5 . ? -10.909 -10.874 11.663 1.00 25.07 ? 510 EDO A O1 1 HETATM 6538 C C2 . EDO L 5 . ? -11.401 -10.094 13.888 1.00 26.47 ? 510 EDO A C2 1 HETATM 6539 O O2 . EDO L 5 . ? -12.235 -8.940 13.722 1.00 27.57 ? 510 EDO A O2 1 HETATM 6540 C C1 . EDO M 5 . ? -6.299 -11.431 -3.749 1.00 24.64 ? 511 EDO A C1 1 HETATM 6541 O O1 . EDO M 5 . ? -6.712 -12.187 -2.622 1.00 22.27 ? 511 EDO A O1 1 HETATM 6542 C C2 . EDO M 5 . ? -5.366 -10.313 -3.306 1.00 31.32 ? 511 EDO A C2 1 HETATM 6543 O O2 . EDO M 5 . ? -5.242 -9.392 -4.393 1.00 20.95 ? 511 EDO A O2 1 HETATM 6544 P P1 . PC N 6 . ? 1.661 -3.308 -5.306 1.00 33.01 ? 512 PC A P1 1 HETATM 6545 O O1 . PC N 6 . ? 2.614 -4.287 -5.997 1.00 38.15 ? 512 PC A O1 1 HETATM 6546 O O3 . PC N 6 . ? 2.544 -2.508 -4.374 1.00 27.93 ? 512 PC A O3 1 HETATM 6547 O O4 . PC N 6 . ? 0.571 -4.039 -4.555 1.00 24.09 ? 512 PC A O4 1 HETATM 6548 O O2 . PC N 6 . ? 1.011 -2.464 -6.440 1.00 25.19 ? 512 PC A O2 1 HETATM 6549 C C1 . PC N 6 . ? 1.806 -1.576 -7.148 1.00 38.73 ? 512 PC A C1 1 HETATM 6550 C C2 . PC N 6 . ? 1.240 -0.162 -7.352 1.00 36.23 ? 512 PC A C2 1 HETATM 6551 N N1 . PC N 6 . ? 0.036 0.094 -8.183 1.00 36.84 ? 512 PC A N1 1 HETATM 6552 C C3 . PC N 6 . ? -0.139 1.554 -8.287 1.00 30.66 ? 512 PC A C3 1 HETATM 6553 C C4 . PC N 6 . ? -1.130 -0.464 -7.512 1.00 36.10 ? 512 PC A C4 1 HETATM 6554 C C5 . PC N 6 . ? 0.044 -0.404 -9.570 1.00 38.95 ? 512 PC A C5 1 HETATM 6555 C C1 . EDO O 5 . ? -5.081 4.223 -9.727 1.00 30.49 ? 513 EDO A C1 1 HETATM 6556 O O1 . EDO O 5 . ? -6.195 3.667 -9.009 1.00 27.34 ? 513 EDO A O1 1 HETATM 6557 C C2 . EDO O 5 . ? -5.151 3.865 -11.210 1.00 38.11 ? 513 EDO A C2 1 HETATM 6558 O O2 . EDO O 5 . ? -6.477 4.048 -11.715 1.00 43.85 ? 513 EDO A O2 1 HETATM 6559 C C1 . NAG P 2 . ? 34.575 -9.286 37.681 1.00 42.71 ? 501 NAG B C1 1 HETATM 6560 C C2 . NAG P 2 . ? 35.545 -8.474 38.542 1.00 41.85 ? 501 NAG B C2 1 HETATM 6561 C C3 . NAG P 2 . ? 36.899 -8.382 37.852 1.00 50.05 ? 501 NAG B C3 1 HETATM 6562 C C4 . NAG P 2 . ? 37.435 -9.778 37.579 1.00 46.23 ? 501 NAG B C4 1 HETATM 6563 C C5 . NAG P 2 . ? 36.420 -10.580 36.764 1.00 47.02 ? 501 NAG B C5 1 HETATM 6564 C C6 . NAG P 2 . ? 36.821 -12.027 36.589 1.00 45.33 ? 501 NAG B C6 1 HETATM 6565 C C7 . NAG P 2 . ? 34.594 -6.802 40.061 1.00 37.29 ? 501 NAG B C7 1 HETATM 6566 C C8 . NAG P 2 . ? 34.128 -5.387 40.213 1.00 48.36 ? 501 NAG B C8 1 HETATM 6567 N N2 . NAG P 2 . ? 35.037 -7.146 38.847 1.00 39.76 ? 501 NAG B N2 1 HETATM 6568 O O3 . NAG P 2 . ? 37.813 -7.657 38.667 1.00 50.91 ? 501 NAG B O3 1 HETATM 6569 O O4 . NAG P 2 . ? 38.655 -9.673 36.853 1.00 55.19 ? 501 NAG B O4 1 HETATM 6570 O O5 . NAG P 2 . ? 35.138 -10.586 37.417 1.00 37.97 ? 501 NAG B O5 1 HETATM 6571 O O6 . NAG P 2 . ? 36.880 -12.706 37.837 1.00 45.99 ? 501 NAG B O6 1 HETATM 6572 O O7 . NAG P 2 . ? 34.564 -7.602 40.993 1.00 39.36 ? 501 NAG B O7 1 HETATM 6573 C C1 . NAG Q 2 . ? 7.791 -41.086 25.920 1.00 65.34 ? 502 NAG B C1 1 HETATM 6574 C C2 . NAG Q 2 . ? 6.572 -42.001 25.823 1.00 67.31 ? 502 NAG B C2 1 HETATM 6575 C C3 . NAG Q 2 . ? 6.811 -43.113 24.805 1.00 68.80 ? 502 NAG B C3 1 HETATM 6576 C C4 . NAG Q 2 . ? 7.237 -42.527 23.466 1.00 68.11 ? 502 NAG B C4 1 HETATM 6577 C C5 . NAG Q 2 . ? 8.454 -41.636 23.663 1.00 66.01 ? 502 NAG B C5 1 HETATM 6578 C C6 . NAG Q 2 . ? 8.884 -40.930 22.397 1.00 61.35 ? 502 NAG B C6 1 HETATM 6579 C C7 . NAG Q 2 . ? 5.146 -42.232 27.812 1.00 69.00 ? 502 NAG B C7 1 HETATM 6580 C C8 . NAG Q 2 . ? 4.975 -42.903 29.138 1.00 63.53 ? 502 NAG B C8 1 HETATM 6581 N N2 . NAG Q 2 . ? 6.247 -42.562 27.125 1.00 68.63 ? 502 NAG B N2 1 HETATM 6582 O O3 . NAG Q 2 . ? 5.611 -43.866 24.661 1.00 72.37 ? 502 NAG B O3 1 HETATM 6583 O O4 . NAG Q 2 . ? 7.570 -43.557 22.542 1.00 71.92 ? 502 NAG B O4 1 HETATM 6584 O O5 . NAG Q 2 . ? 8.147 -40.616 24.622 1.00 66.86 ? 502 NAG B O5 1 HETATM 6585 O O6 . NAG Q 2 . ? 7.769 -40.541 21.604 1.00 64.63 ? 502 NAG B O6 1 HETATM 6586 O O7 . NAG Q 2 . ? 4.322 -41.430 27.378 1.00 74.50 ? 502 NAG B O7 1 HETATM 6587 C C1 . FUL R 3 . ? 7.591 -39.131 21.402 1.00 64.04 ? 503 FUL B C1 1 HETATM 6588 C C2 . FUL R 3 . ? 7.194 -38.450 22.715 1.00 59.75 ? 503 FUL B C2 1 HETATM 6589 O O2 . FUL R 3 . ? 8.227 -38.450 23.659 1.00 68.42 ? 503 FUL B O2 1 HETATM 6590 C C3 . FUL R 3 . ? 6.765 -37.040 22.540 1.00 64.12 ? 503 FUL B C3 1 HETATM 6591 O O3 . FUL R 3 . ? 6.344 -36.578 23.823 1.00 70.94 ? 503 FUL B O3 1 HETATM 6592 C C4 . FUL R 3 . ? 5.563 -36.975 21.650 1.00 64.43 ? 503 FUL B C4 1 HETATM 6593 O O4 . FUL R 3 . ? 4.451 -37.526 22.336 1.00 75.49 ? 503 FUL B O4 1 HETATM 6594 C C5 . FUL R 3 . ? 5.791 -37.741 20.329 1.00 64.22 ? 503 FUL B C5 1 HETATM 6595 C C6 . FUL R 3 . ? 4.477 -38.197 19.742 1.00 63.92 ? 503 FUL B C6 1 HETATM 6596 O O5 . FUL R 3 . ? 6.600 -38.955 20.417 1.00 65.83 ? 503 FUL B O5 1 HETATM 6597 C C1 . NAG S 2 . ? 6.474 -43.824 21.652 1.00 71.22 ? 504 NAG B C1 1 HETATM 6598 C C2 . NAG S 2 . ? 7.048 -44.504 20.394 1.00 71.51 ? 504 NAG B C2 1 HETATM 6599 C C3 . NAG S 2 . ? 5.935 -45.114 19.537 1.00 78.51 ? 504 NAG B C3 1 HETATM 6600 C C4 . NAG S 2 . ? 5.009 -45.981 20.377 1.00 80.83 ? 504 NAG B C4 1 HETATM 6601 C C5 . NAG S 2 . ? 4.482 -45.158 21.540 1.00 76.62 ? 504 NAG B C5 1 HETATM 6602 C C6 . NAG S 2 . ? 3.576 -45.938 22.460 1.00 78.03 ? 504 NAG B C6 1 HETATM 6603 C C7 . NAG S 2 . ? 9.153 -43.568 19.538 1.00 65.85 ? 504 NAG B C7 1 HETATM 6604 C C8 . NAG S 2 . ? 9.773 -42.519 18.667 1.00 64.66 ? 504 NAG B C8 1 HETATM 6605 N N2 . NAG S 2 . ? 7.819 -43.555 19.607 1.00 66.22 ? 504 NAG B N2 1 HETATM 6606 O O3 . NAG S 2 . ? 6.522 -45.897 18.504 1.00 75.78 ? 504 NAG B O3 1 HETATM 6607 O O4 . NAG S 2 . ? 3.915 -46.442 19.592 1.00 84.38 ? 504 NAG B O4 1 HETATM 6608 O O5 . NAG S 2 . ? 5.593 -44.715 22.326 1.00 75.06 ? 504 NAG B O5 1 HETATM 6609 O O6 . NAG S 2 . ? 2.211 -45.759 22.106 1.00 81.79 ? 504 NAG B O6 1 HETATM 6610 O O7 . NAG S 2 . ? 9.829 -44.387 20.153 1.00 65.64 ? 504 NAG B O7 1 HETATM 6611 C C1 . NAG T 2 . ? 24.844 0.265 24.432 1.00 39.03 ? 505 NAG B C1 1 HETATM 6612 C C2 . NAG T 2 . ? 25.661 0.814 23.251 1.00 43.91 ? 505 NAG B C2 1 HETATM 6613 C C3 . NAG T 2 . ? 27.162 0.789 23.562 1.00 39.71 ? 505 NAG B C3 1 HETATM 6614 C C4 . NAG T 2 . ? 27.469 1.392 24.927 1.00 39.76 ? 505 NAG B C4 1 HETATM 6615 C C5 . NAG T 2 . ? 26.581 0.752 25.990 1.00 42.41 ? 505 NAG B C5 1 HETATM 6616 C C6 . NAG T 2 . ? 26.750 1.358 27.366 1.00 37.21 ? 505 NAG B C6 1 HETATM 6617 C C7 . NAG T 2 . ? 24.643 0.505 21.037 1.00 44.55 ? 505 NAG B C7 1 HETATM 6618 C C8 . NAG T 2 . ? 24.482 -0.421 19.869 1.00 45.99 ? 505 NAG B C8 1 HETATM 6619 N N2 . NAG T 2 . ? 25.392 0.050 22.043 1.00 40.55 ? 505 NAG B N2 1 HETATM 6620 O O3 . NAG T 2 . ? 27.844 1.527 22.554 1.00 50.07 ? 505 NAG B O3 1 HETATM 6621 O O4 . NAG T 2 . ? 28.835 1.136 25.235 1.00 44.66 ? 505 NAG B O4 1 HETATM 6622 O O5 . NAG T 2 . ? 25.209 0.943 25.625 1.00 34.99 ? 505 NAG B O5 1 HETATM 6623 O O6 . NAG T 2 . ? 26.404 2.736 27.358 1.00 40.22 ? 505 NAG B O6 1 HETATM 6624 O O7 . NAG T 2 . ? 24.113 1.611 21.070 1.00 48.00 ? 505 NAG B O7 1 HETATM 6625 C C1 . NAG U 2 . ? 29.532 2.319 25.671 1.00 46.16 ? 506 NAG B C1 1 HETATM 6626 C C2 . NAG U 2 . ? 30.824 1.915 26.382 1.00 49.59 ? 506 NAG B C2 1 HETATM 6627 C C3 . NAG U 2 . ? 31.566 3.160 26.870 1.00 56.21 ? 506 NAG B C3 1 HETATM 6628 C C4 . NAG U 2 . ? 31.769 4.143 25.725 1.00 60.44 ? 506 NAG B C4 1 HETATM 6629 C C5 . NAG U 2 . ? 30.438 4.434 25.037 1.00 58.61 ? 506 NAG B C5 1 HETATM 6630 C C6 . NAG U 2 . ? 30.583 5.309 23.814 1.00 58.28 ? 506 NAG B C6 1 HETATM 6631 C C7 . NAG U 2 . ? 30.580 -0.318 27.392 1.00 43.97 ? 506 NAG B C7 1 HETATM 6632 C C8 . NAG U 2 . ? 30.273 -1.078 28.646 1.00 49.71 ? 506 NAG B C8 1 HETATM 6633 N N2 . NAG U 2 . ? 30.551 1.017 27.493 1.00 42.50 ? 506 NAG B N2 1 HETATM 6634 O O3 . NAG U 2 . ? 32.824 2.799 27.428 1.00 51.17 ? 506 NAG B O3 1 HETATM 6635 O O4 . NAG U 2 . ? 32.319 5.358 26.225 1.00 71.39 ? 506 NAG B O4 1 HETATM 6636 O O5 . NAG U 2 . ? 29.831 3.207 24.602 1.00 54.90 ? 506 NAG B O5 1 HETATM 6637 O O6 . NAG U 2 . ? 30.088 6.619 24.060 1.00 64.56 ? 506 NAG B O6 1 HETATM 6638 O O7 . NAG U 2 . ? 30.843 -0.886 26.338 1.00 51.25 ? 506 NAG B O7 1 HETATM 6639 ZN ZN . ZN V 4 . ? 13.468 -18.867 28.705 1.00 31.36 ? 507 ZN B ZN 1 HETATM 6640 ZN ZN . ZN W 4 . ? 13.022 -22.606 26.997 1.00 33.27 ? 508 ZN B ZN 1 HETATM 6641 C C1 . EDO X 5 . ? 27.138 -5.068 15.945 1.00 38.29 ? 509 EDO B C1 1 HETATM 6642 O O1 . EDO X 5 . ? 26.483 -6.198 16.547 1.00 33.82 ? 509 EDO B O1 1 HETATM 6643 C C2 . EDO X 5 . ? 26.353 -3.784 16.177 1.00 35.88 ? 509 EDO B C2 1 HETATM 6644 O O2 . EDO X 5 . ? 26.840 -3.133 17.353 1.00 38.61 ? 509 EDO B O2 1 HETATM 6645 P P1 . PC Y 6 . ? 15.460 -21.551 28.329 1.00 36.96 ? 510 PC B P1 1 HETATM 6646 O O1 . PC Y 6 . ? 16.460 -20.785 27.497 1.00 27.27 ? 510 PC B O1 1 HETATM 6647 O O3 . PC Y 6 . ? 15.002 -22.849 27.670 1.00 36.12 ? 510 PC B O3 1 HETATM 6648 O O4 . PC Y 6 . ? 14.233 -20.723 28.548 1.00 31.15 ? 510 PC B O4 1 HETATM 6649 O O2 . PC Y 6 . ? 16.091 -21.904 29.724 1.00 32.22 ? 510 PC B O2 1 HETATM 6650 C C1 . PC Y 6 . ? 15.265 -22.487 30.671 1.00 33.29 ? 510 PC B C1 1 HETATM 6651 C C2 . PC Y 6 . ? 15.375 -21.986 32.122 1.00 38.51 ? 510 PC B C2 1 HETATM 6652 N N1 . PC Y 6 . ? 16.569 -22.212 32.980 1.00 37.95 ? 510 PC B N1 1 HETATM 6653 C C3 . PC Y 6 . ? 16.186 -21.851 34.358 1.00 36.63 ? 510 PC B C3 1 HETATM 6654 C C4 . PC Y 6 . ? 17.649 -21.355 32.511 1.00 34.67 ? 510 PC B C4 1 HETATM 6655 C C5 . PC Y 6 . ? 17.150 -23.558 33.085 1.00 42.68 ? 510 PC B C5 1 HETATM 6656 C C1 . EDO Z 5 . ? 20.832 -21.835 38.325 1.00 39.34 ? 511 EDO B C1 1 HETATM 6657 O O1 . EDO Z 5 . ? 21.823 -21.902 39.355 1.00 43.54 ? 511 EDO B O1 1 HETATM 6658 C C2 . EDO Z 5 . ? 20.311 -20.405 38.244 1.00 35.62 ? 511 EDO B C2 1 HETATM 6659 O O2 . EDO Z 5 . ? 21.308 -19.533 37.686 1.00 28.46 ? 511 EDO B O2 1 HETATM 6660 O O . HOH AA 7 . ? 15.292 -18.285 -8.104 1.00 42.28 ? 601 HOH A O 1 HETATM 6661 O O . HOH AA 7 . ? -17.215 0.060 -15.835 1.00 43.41 ? 602 HOH A O 1 HETATM 6662 O O . HOH AA 7 . ? 16.434 -9.361 -12.117 1.00 33.23 ? 603 HOH A O 1 HETATM 6663 O O . HOH AA 7 . ? -4.891 -1.303 16.680 1.00 41.12 ? 604 HOH A O 1 HETATM 6664 O O . HOH AA 7 . ? 9.346 21.232 -11.191 1.00 38.53 ? 605 HOH A O 1 HETATM 6665 O O . HOH AA 7 . ? 1.961 -27.376 -14.200 1.00 47.19 ? 606 HOH A O 1 HETATM 6666 O O . HOH AA 7 . ? 0.879 0.387 5.306 1.00 22.70 ? 607 HOH A O 1 HETATM 6667 O O . HOH AA 7 . ? 7.623 -22.985 3.667 1.00 40.36 ? 608 HOH A O 1 HETATM 6668 O O . HOH AA 7 . ? 17.494 -9.002 -3.201 1.00 30.36 ? 609 HOH A O 1 HETATM 6669 O O . HOH AA 7 . ? -4.221 20.731 6.720 1.00 41.78 ? 610 HOH A O 1 HETATM 6670 O O . HOH AA 7 . ? 1.929 -32.733 0.999 1.00 50.56 ? 611 HOH A O 1 HETATM 6671 O O . HOH AA 7 . ? -15.417 -9.897 -13.715 1.00 34.40 ? 612 HOH A O 1 HETATM 6672 O O . HOH AA 7 . ? 10.809 -11.549 6.887 1.00 23.83 ? 613 HOH A O 1 HETATM 6673 O O . HOH AA 7 . ? 17.181 -8.271 1.501 1.00 47.29 ? 614 HOH A O 1 HETATM 6674 O O . HOH AA 7 . ? 12.244 1.490 -12.492 1.00 48.63 ? 615 HOH A O 1 HETATM 6675 O O . HOH AA 7 . ? 3.303 14.296 22.859 1.00 40.68 ? 616 HOH A O 1 HETATM 6676 O O . HOH AA 7 . ? -1.029 -9.237 14.158 1.00 35.97 ? 617 HOH A O 1 HETATM 6677 O O . HOH AA 7 . ? -7.844 -34.220 -7.548 1.00 53.34 ? 618 HOH A O 1 HETATM 6678 O O . HOH AA 7 . ? 14.899 26.816 -3.398 1.00 41.72 ? 619 HOH A O 1 HETATM 6679 O O . HOH AA 7 . ? -13.832 2.480 16.198 1.00 35.85 ? 620 HOH A O 1 HETATM 6680 O O . HOH AA 7 . ? 0.912 -19.979 4.633 1.00 29.67 ? 621 HOH A O 1 HETATM 6681 O O . HOH AA 7 . ? 4.424 15.408 -11.773 1.00 29.01 ? 622 HOH A O 1 HETATM 6682 O O . HOH AA 7 . ? -9.772 25.698 2.618 1.00 43.83 ? 623 HOH A O 1 HETATM 6683 O O . HOH AA 7 . ? -9.372 -12.000 10.009 1.00 20.12 ? 624 HOH A O 1 HETATM 6684 O O . HOH AA 7 . ? -0.159 28.859 3.700 1.00 56.10 ? 625 HOH A O 1 HETATM 6685 O O . HOH AA 7 . ? 12.351 -4.327 7.320 1.00 30.39 ? 626 HOH A O 1 HETATM 6686 O O . HOH AA 7 . ? -13.218 -21.796 -14.663 1.00 46.70 ? 627 HOH A O 1 HETATM 6687 O O . HOH AA 7 . ? 17.960 -9.723 0.210 1.00 41.96 ? 628 HOH A O 1 HETATM 6688 O O . HOH AA 7 . ? 10.930 -15.072 7.825 1.00 41.10 ? 629 HOH A O 1 HETATM 6689 O O . HOH AA 7 . ? -10.045 7.152 -15.153 1.00 42.11 ? 630 HOH A O 1 HETATM 6690 O O . HOH AA 7 . ? 20.005 11.732 15.019 1.00 52.01 ? 631 HOH A O 1 HETATM 6691 O O . HOH AA 7 . ? 3.481 -27.392 -5.174 1.00 46.16 ? 632 HOH A O 1 HETATM 6692 O O . HOH AA 7 . ? 3.494 -16.482 8.660 1.00 45.59 ? 633 HOH A O 1 HETATM 6693 O O . HOH AA 7 . ? 5.647 6.869 -16.748 1.00 45.26 ? 634 HOH A O 1 HETATM 6694 O O . HOH AA 7 . ? -13.376 -5.484 12.449 1.00 35.38 ? 635 HOH A O 1 HETATM 6695 O O . HOH AA 7 . ? 4.925 5.245 18.335 1.00 33.30 ? 636 HOH A O 1 HETATM 6696 O O . HOH AA 7 . ? -15.573 -6.212 -14.345 1.00 28.25 ? 637 HOH A O 1 HETATM 6697 O O . HOH AA 7 . ? -17.075 -25.259 5.768 1.00 51.49 ? 638 HOH A O 1 HETATM 6698 O O . HOH AA 7 . ? -8.902 3.204 -11.688 1.00 36.75 ? 639 HOH A O 1 HETATM 6699 O O . HOH AA 7 . ? -17.680 13.063 6.714 1.00 37.09 ? 640 HOH A O 1 HETATM 6700 O O . HOH AA 7 . ? 15.567 -11.830 -4.756 1.00 32.76 ? 641 HOH A O 1 HETATM 6701 O O . HOH AA 7 . ? -6.715 -10.774 -0.416 1.00 21.65 ? 642 HOH A O 1 HETATM 6702 O O . HOH AA 7 . ? 1.582 0.490 -13.737 1.00 33.16 ? 643 HOH A O 1 HETATM 6703 O O . HOH AA 7 . ? -3.648 29.197 2.952 1.00 50.00 ? 644 HOH A O 1 HETATM 6704 O O . HOH AA 7 . ? 1.458 8.082 -13.591 1.00 31.44 ? 645 HOH A O 1 HETATM 6705 O O . HOH AA 7 . ? 19.342 16.266 3.824 1.00 43.46 ? 646 HOH A O 1 HETATM 6706 O O . HOH AA 7 . ? -3.702 -3.224 19.025 1.00 50.74 ? 647 HOH A O 1 HETATM 6707 O O . HOH AA 7 . ? -12.105 22.380 -3.672 1.00 29.69 ? 648 HOH A O 1 HETATM 6708 O O . HOH AA 7 . ? 9.367 -19.343 3.977 1.00 40.32 ? 649 HOH A O 1 HETATM 6709 O O . HOH AA 7 . ? 8.249 22.688 7.885 1.00 37.31 ? 650 HOH A O 1 HETATM 6710 O O . HOH AA 7 . ? 5.521 9.800 -16.844 1.00 39.45 ? 651 HOH A O 1 HETATM 6711 O O . HOH AA 7 . ? 16.525 9.815 -10.810 1.00 37.20 ? 652 HOH A O 1 HETATM 6712 O O . HOH AA 7 . ? -11.591 -9.656 -14.732 1.00 42.92 ? 653 HOH A O 1 HETATM 6713 O O . HOH AA 7 . ? -11.965 9.839 6.810 1.00 23.58 ? 654 HOH A O 1 HETATM 6714 O O . HOH AA 7 . ? -17.680 -20.115 -4.671 1.00 31.34 ? 655 HOH A O 1 HETATM 6715 O O . HOH AA 7 . ? -22.914 10.499 -8.072 1.00 46.38 ? 656 HOH A O 1 HETATM 6716 O O . HOH AA 7 . ? -5.798 6.058 13.182 1.00 22.28 ? 657 HOH A O 1 HETATM 6717 O O . HOH AA 7 . ? -12.084 6.249 9.778 1.00 23.20 ? 658 HOH A O 1 HETATM 6718 O O . HOH AA 7 . ? 4.584 -27.214 -2.388 1.00 33.22 ? 659 HOH A O 1 HETATM 6719 O O . HOH AA 7 . ? 14.780 -1.980 -15.425 1.00 36.76 ? 660 HOH A O 1 HETATM 6720 O O . HOH AA 7 . ? 7.037 21.628 -11.242 1.00 42.03 ? 661 HOH A O 1 HETATM 6721 O O . HOH AA 7 . ? -15.633 6.663 -10.040 1.00 21.46 ? 662 HOH A O 1 HETATM 6722 O O . HOH AA 7 . ? 11.964 -14.199 1.271 1.00 26.42 ? 663 HOH A O 1 HETATM 6723 O O . HOH AA 7 . ? 2.389 13.571 -15.120 1.00 33.21 ? 664 HOH A O 1 HETATM 6724 O O . HOH AA 7 . ? 20.954 11.570 -1.778 1.00 34.68 ? 665 HOH A O 1 HETATM 6725 O O . HOH AA 7 . ? 4.951 -1.774 -8.695 1.00 32.76 ? 666 HOH A O 1 HETATM 6726 O O . HOH AA 7 . ? -21.643 12.164 5.303 1.00 52.75 ? 667 HOH A O 1 HETATM 6727 O O . HOH AA 7 . ? -4.263 4.928 9.354 1.00 18.43 ? 668 HOH A O 1 HETATM 6728 O O . HOH AA 7 . ? 5.672 -6.584 9.454 1.00 24.29 ? 669 HOH A O 1 HETATM 6729 O O . HOH AA 7 . ? -9.993 -13.603 -0.214 1.00 25.21 ? 670 HOH A O 1 HETATM 6730 O O . HOH AA 7 . ? -22.607 -5.832 -4.922 1.00 45.02 ? 671 HOH A O 1 HETATM 6731 O O . HOH AA 7 . ? -12.715 -10.386 -3.772 1.00 20.81 ? 672 HOH A O 1 HETATM 6732 O O . HOH AA 7 . ? -7.702 25.024 -6.841 1.00 37.72 ? 673 HOH A O 1 HETATM 6733 O O . HOH AA 7 . ? -11.302 12.676 -9.146 1.00 25.20 ? 674 HOH A O 1 HETATM 6734 O O . HOH AA 7 . ? 7.172 6.371 -9.057 1.00 21.65 ? 675 HOH A O 1 HETATM 6735 O O . HOH AA 7 . ? -21.887 13.098 -9.038 1.00 28.54 ? 676 HOH A O 1 HETATM 6736 O O . HOH AA 7 . ? -23.251 4.458 1.387 1.00 50.84 ? 677 HOH A O 1 HETATM 6737 O O . HOH AA 7 . ? 11.605 -18.821 0.894 1.00 37.77 ? 678 HOH A O 1 HETATM 6738 O O . HOH AA 7 . ? 8.780 32.850 -2.793 1.00 38.70 ? 679 HOH A O 1 HETATM 6739 O O . HOH AA 7 . ? -3.966 24.913 -9.754 1.00 45.77 ? 680 HOH A O 1 HETATM 6740 O O . HOH AA 7 . ? 18.196 19.880 2.916 1.00 38.16 ? 681 HOH A O 1 HETATM 6741 O O . HOH AA 7 . ? -2.189 11.741 -15.354 1.00 35.12 ? 682 HOH A O 1 HETATM 6742 O O . HOH AA 7 . ? -14.710 0.008 -0.030 1.00 18.18 ? 683 HOH A O 1 HETATM 6743 O O . HOH AA 7 . ? -2.058 -25.956 1.862 1.00 29.48 ? 684 HOH A O 1 HETATM 6744 O O . HOH AA 7 . ? -16.112 16.109 6.855 1.00 33.75 ? 685 HOH A O 1 HETATM 6745 O O . HOH AA 7 . ? -11.756 21.343 -8.559 1.00 40.80 ? 686 HOH A O 1 HETATM 6746 O O . HOH AA 7 . ? -6.591 27.056 1.696 1.00 41.98 ? 687 HOH A O 1 HETATM 6747 O O . HOH AA 7 . ? -2.798 -33.347 -8.269 1.00 40.51 ? 688 HOH A O 1 HETATM 6748 O O . HOH AA 7 . ? 2.759 17.821 -11.054 1.00 33.23 ? 689 HOH A O 1 HETATM 6749 O O . HOH AA 7 . ? -18.191 -6.800 5.852 1.00 31.87 ? 690 HOH A O 1 HETATM 6750 O O . HOH AA 7 . ? 6.613 23.976 -9.111 1.00 36.68 ? 691 HOH A O 1 HETATM 6751 O O . HOH AA 7 . ? 12.803 -3.310 10.802 1.00 28.47 ? 692 HOH A O 1 HETATM 6752 O O . HOH AA 7 . ? -11.604 -3.514 19.341 1.00 48.16 ? 693 HOH A O 1 HETATM 6753 O O . HOH AA 7 . ? -8.252 25.474 -4.653 1.00 31.68 ? 694 HOH A O 1 HETATM 6754 O O . HOH AA 7 . ? 16.099 0.250 -13.753 1.00 40.36 ? 695 HOH A O 1 HETATM 6755 O O . HOH AA 7 . ? -6.665 -6.155 7.326 1.00 23.47 ? 696 HOH A O 1 HETATM 6756 O O . HOH AA 7 . ? 14.231 10.678 14.493 1.00 29.64 ? 697 HOH A O 1 HETATM 6757 O O . HOH AA 7 . ? 19.115 -1.990 4.357 1.00 43.58 ? 698 HOH A O 1 HETATM 6758 O O . HOH AA 7 . ? -10.909 -0.535 17.056 1.00 35.19 ? 699 HOH A O 1 HETATM 6759 O O . HOH AA 7 . ? -20.882 11.349 1.217 1.00 37.40 ? 700 HOH A O 1 HETATM 6760 O O . HOH AA 7 . ? 12.666 6.361 -7.336 1.00 21.31 ? 701 HOH A O 1 HETATM 6761 O O . HOH AA 7 . ? 5.197 20.176 -13.298 1.00 40.00 ? 702 HOH A O 1 HETATM 6762 O O . HOH AA 7 . ? 11.135 -2.273 -2.537 1.00 19.71 ? 703 HOH A O 1 HETATM 6763 O O . HOH AA 7 . ? -17.082 -1.616 -0.633 1.00 26.73 ? 704 HOH A O 1 HETATM 6764 O O . HOH AA 7 . ? -8.288 16.343 15.118 1.00 42.17 ? 705 HOH A O 1 HETATM 6765 O O . HOH AA 7 . ? -10.253 -12.820 -13.220 1.00 42.79 ? 706 HOH A O 1 HETATM 6766 O O . HOH AA 7 . ? 8.876 -17.672 -5.312 1.00 24.75 ? 707 HOH A O 1 HETATM 6767 O O . HOH AA 7 . ? -17.083 -28.803 -12.199 1.00 51.69 ? 708 HOH A O 1 HETATM 6768 O O . HOH AA 7 . ? 12.932 -15.020 -8.320 1.00 27.20 ? 709 HOH A O 1 HETATM 6769 O O . HOH AA 7 . ? 17.167 1.909 -10.388 1.00 29.87 ? 710 HOH A O 1 HETATM 6770 O O . HOH AA 7 . ? -16.298 -11.858 -3.123 1.00 30.77 ? 711 HOH A O 1 HETATM 6771 O O . HOH AA 7 . ? 20.766 -6.642 -9.603 1.00 35.47 ? 712 HOH A O 1 HETATM 6772 O O . HOH AA 7 . ? -15.144 14.459 11.250 1.00 40.78 ? 713 HOH A O 1 HETATM 6773 O O . HOH AA 7 . ? 13.683 -6.634 6.740 1.00 31.07 ? 714 HOH A O 1 HETATM 6774 O O . HOH AA 7 . ? -11.408 -17.545 2.574 1.00 23.27 ? 715 HOH A O 1 HETATM 6775 O O . HOH AA 7 . ? -4.318 -6.598 9.294 1.00 24.15 ? 716 HOH A O 1 HETATM 6776 O O . HOH AA 7 . ? -1.284 -11.850 -3.606 1.00 23.69 ? 717 HOH A O 1 HETATM 6777 O O . HOH AA 7 . ? -16.813 -5.217 8.455 1.00 35.73 ? 718 HOH A O 1 HETATM 6778 O O . HOH AA 7 . ? -15.496 -29.931 4.019 1.00 49.61 ? 719 HOH A O 1 HETATM 6779 O O . HOH AA 7 . ? -20.160 -26.034 -2.765 1.00 47.62 ? 720 HOH A O 1 HETATM 6780 O O . HOH AA 7 . ? 12.727 -1.868 -13.892 1.00 34.82 ? 721 HOH A O 1 HETATM 6781 O O . HOH AA 7 . ? -14.444 -6.813 1.524 1.00 18.95 ? 722 HOH A O 1 HETATM 6782 O O . HOH AA 7 . ? -10.813 15.525 -8.803 1.00 27.12 ? 723 HOH A O 1 HETATM 6783 O O . HOH AA 7 . ? -14.524 8.158 -12.112 1.00 35.23 ? 724 HOH A O 1 HETATM 6784 O O . HOH AA 7 . ? -11.385 10.122 -4.728 1.00 21.45 ? 725 HOH A O 1 HETATM 6785 O O . HOH AA 7 . ? 6.420 -5.920 -12.945 1.00 37.72 ? 726 HOH A O 1 HETATM 6786 O O . HOH AA 7 . ? -10.118 -11.162 -3.817 1.00 23.72 ? 727 HOH A O 1 HETATM 6787 O O . HOH AA 7 . ? -2.846 -20.709 10.347 1.00 43.05 ? 728 HOH A O 1 HETATM 6788 O O . HOH AA 7 . ? 9.434 11.875 -17.012 1.00 32.80 ? 729 HOH A O 1 HETATM 6789 O O . HOH AA 7 . ? -4.875 8.084 -9.454 1.00 25.62 ? 730 HOH A O 1 HETATM 6790 O O . HOH AA 7 . ? 8.227 3.768 -4.327 1.00 20.41 ? 731 HOH A O 1 HETATM 6791 O O . HOH AA 7 . ? -1.170 -8.216 -6.174 1.00 26.04 ? 732 HOH A O 1 HETATM 6792 O O . HOH AA 7 . ? 2.699 -15.124 -18.188 1.00 44.81 ? 733 HOH A O 1 HETATM 6793 O O . HOH AA 7 . ? 12.273 2.082 9.461 1.00 24.87 ? 734 HOH A O 1 HETATM 6794 O O . HOH AA 7 . ? -18.151 12.653 -10.798 1.00 41.93 ? 735 HOH A O 1 HETATM 6795 O O . HOH AA 7 . ? -21.354 6.505 -4.640 1.00 31.37 ? 736 HOH A O 1 HETATM 6796 O O . HOH AA 7 . ? 18.688 1.217 1.708 1.00 32.15 ? 737 HOH A O 1 HETATM 6797 O O . HOH AA 7 . ? -21.973 13.716 -6.376 1.00 36.83 ? 738 HOH A O 1 HETATM 6798 O O . HOH AA 7 . ? -19.672 7.961 -5.531 1.00 27.65 ? 739 HOH A O 1 HETATM 6799 O O . HOH AA 7 . ? 1.322 28.827 -6.864 1.00 49.01 ? 740 HOH A O 1 HETATM 6800 O O . HOH AA 7 . ? 14.268 -10.429 1.557 1.00 37.13 ? 741 HOH A O 1 HETATM 6801 O O . HOH AA 7 . ? -0.439 19.636 9.283 1.00 27.58 ? 742 HOH A O 1 HETATM 6802 O O . HOH AA 7 . ? 2.687 -15.454 4.543 1.00 22.86 ? 743 HOH A O 1 HETATM 6803 O O . HOH AA 7 . ? 19.305 -9.997 -17.960 1.00 62.98 ? 744 HOH A O 1 HETATM 6804 O O . HOH AA 7 . ? -8.738 5.724 17.182 1.00 30.83 ? 745 HOH A O 1 HETATM 6805 O O . HOH AA 7 . ? -6.658 4.487 -2.074 1.00 19.68 ? 746 HOH A O 1 HETATM 6806 O O . HOH AA 7 . ? 13.167 4.968 14.709 1.00 29.95 ? 747 HOH A O 1 HETATM 6807 O O . HOH AA 7 . ? -5.680 -15.398 -11.050 1.00 46.97 ? 748 HOH A O 1 HETATM 6808 O O . HOH AA 7 . ? -3.506 6.404 16.104 1.00 25.51 ? 749 HOH A O 1 HETATM 6809 O O . HOH AA 7 . ? 0.651 -26.626 4.361 1.00 41.24 ? 750 HOH A O 1 HETATM 6810 O O . HOH AA 7 . ? 25.814 -1.268 12.926 1.00 45.41 ? 751 HOH A O 1 HETATM 6811 O O . HOH AA 7 . ? -18.087 13.831 -9.182 1.00 30.60 ? 752 HOH A O 1 HETATM 6812 O O . HOH AA 7 . ? 0.434 -10.436 -5.540 1.00 22.91 ? 753 HOH A O 1 HETATM 6813 O O . HOH AA 7 . ? 4.271 -26.356 4.492 1.00 41.06 ? 754 HOH A O 1 HETATM 6814 O O . HOH AA 7 . ? -14.216 -3.006 -16.653 1.00 29.14 ? 755 HOH A O 1 HETATM 6815 O O . HOH AA 7 . ? 2.527 3.492 23.261 1.00 32.78 ? 756 HOH A O 1 HETATM 6816 O O . HOH AA 7 . ? -6.893 18.635 15.497 1.00 42.40 ? 757 HOH A O 1 HETATM 6817 O O . HOH AA 7 . ? -13.620 -11.836 -14.091 1.00 42.16 ? 758 HOH A O 1 HETATM 6818 O O . HOH AA 7 . ? 9.712 -4.110 18.377 1.00 38.09 ? 759 HOH A O 1 HETATM 6819 O O . HOH AA 7 . ? -1.500 -10.397 11.800 1.00 22.30 ? 760 HOH A O 1 HETATM 6820 O O . HOH AA 7 . ? -2.784 -1.984 10.521 1.00 25.61 ? 761 HOH A O 1 HETATM 6821 O O . HOH AA 7 . ? 8.998 -29.089 -0.484 1.00 47.74 ? 762 HOH A O 1 HETATM 6822 O O . HOH AA 7 . ? -7.251 1.730 -1.872 1.00 18.05 ? 763 HOH A O 1 HETATM 6823 O O . HOH AA 7 . ? -9.669 2.737 -9.725 1.00 34.50 ? 764 HOH A O 1 HETATM 6824 O O . HOH AA 7 . ? 3.030 7.171 22.094 1.00 45.79 ? 765 HOH A O 1 HETATM 6825 O O . HOH AA 7 . ? 17.877 -3.690 3.772 1.00 40.80 ? 766 HOH A O 1 HETATM 6826 O O . HOH AA 7 . ? 5.200 7.649 19.454 1.00 39.44 ? 767 HOH A O 1 HETATM 6827 O O . HOH AA 7 . ? 19.998 7.444 -7.983 1.00 36.16 ? 768 HOH A O 1 HETATM 6828 O O . HOH AA 7 . ? 7.897 5.006 -16.051 1.00 46.83 ? 769 HOH A O 1 HETATM 6829 O O . HOH AA 7 . ? 5.727 10.425 -8.089 1.00 25.96 ? 770 HOH A O 1 HETATM 6830 O O . HOH AA 7 . ? -18.350 -1.145 5.464 1.00 41.43 ? 771 HOH A O 1 HETATM 6831 O O . HOH AA 7 . ? 17.687 -5.836 8.628 1.00 41.84 ? 772 HOH A O 1 HETATM 6832 O O . HOH AA 7 . ? 14.304 9.430 20.654 1.00 29.53 ? 773 HOH A O 1 HETATM 6833 O O . HOH AA 7 . ? 10.145 4.259 9.685 1.00 23.46 ? 774 HOH A O 1 HETATM 6834 O O . HOH AA 7 . ? -5.450 5.949 0.009 1.00 15.64 ? 775 HOH A O 1 HETATM 6835 O O . HOH AA 7 . ? -21.091 0.941 -8.166 1.00 21.31 ? 776 HOH A O 1 HETATM 6836 O O . HOH AA 7 . ? -9.769 -23.553 6.799 1.00 34.55 ? 777 HOH A O 1 HETATM 6837 O O . HOH AA 7 . ? 18.719 -8.743 -9.717 1.00 43.54 ? 778 HOH A O 1 HETATM 6838 O O . HOH AA 7 . ? 9.751 18.117 13.296 1.00 27.89 ? 779 HOH A O 1 HETATM 6839 O O . HOH AA 7 . ? 3.291 -1.273 -11.962 1.00 37.27 ? 780 HOH A O 1 HETATM 6840 O O . HOH AA 7 . ? 0.546 18.813 -12.005 1.00 37.33 ? 781 HOH A O 1 HETATM 6841 O O . HOH AA 7 . ? 3.383 -30.354 -1.340 1.00 38.09 ? 782 HOH A O 1 HETATM 6842 O O . HOH AA 7 . ? 11.776 21.670 10.279 1.00 46.43 ? 783 HOH A O 1 HETATM 6843 O O . HOH AA 7 . ? -7.717 -17.020 14.770 1.00 37.76 ? 784 HOH A O 1 HETATM 6844 O O . HOH AA 7 . ? -11.416 -1.759 -19.008 1.00 32.56 ? 785 HOH A O 1 HETATM 6845 O O . HOH AA 7 . ? -2.362 -16.581 14.434 1.00 43.35 ? 786 HOH A O 1 HETATM 6846 O O . HOH AA 7 . ? 6.572 15.736 -14.479 1.00 31.13 ? 787 HOH A O 1 HETATM 6847 O O . HOH AA 7 . ? -13.723 5.963 7.570 1.00 21.83 ? 788 HOH A O 1 HETATM 6848 O O . HOH AA 7 . ? -6.294 -12.365 -11.283 1.00 28.92 ? 789 HOH A O 1 HETATM 6849 O O . HOH AA 7 . ? -0.933 -3.746 11.442 1.00 28.51 ? 790 HOH A O 1 HETATM 6850 O O . HOH AA 7 . ? 15.844 -9.481 4.982 1.00 36.60 ? 791 HOH A O 1 HETATM 6851 O O . HOH AA 7 . ? -5.231 13.367 -14.630 1.00 31.55 ? 792 HOH A O 1 HETATM 6852 O O . HOH AA 7 . ? -3.066 -17.697 -9.267 1.00 38.96 ? 793 HOH A O 1 HETATM 6853 O O . HOH AA 7 . ? 12.312 26.853 -4.355 1.00 37.89 ? 794 HOH A O 1 HETATM 6854 O O . HOH AA 7 . ? -17.591 -2.232 7.458 1.00 43.59 ? 795 HOH A O 1 HETATM 6855 O O . HOH AA 7 . ? -15.569 21.105 -0.956 1.00 42.65 ? 796 HOH A O 1 HETATM 6856 O O . HOH AA 7 . ? 10.292 28.951 5.622 1.00 37.57 ? 797 HOH A O 1 HETATM 6857 O O . HOH AA 7 . ? -5.359 -14.897 15.289 1.00 23.94 ? 798 HOH A O 1 HETATM 6858 O O . HOH AA 7 . ? 6.850 34.953 -1.304 1.00 25.77 ? 799 HOH A O 1 HETATM 6859 O O . HOH AA 7 . ? 16.867 5.177 13.953 1.00 48.29 ? 800 HOH A O 1 HETATM 6860 O O . HOH AA 7 . ? -13.197 22.381 -0.730 1.00 35.90 ? 801 HOH A O 1 HETATM 6861 O O . HOH AA 7 . ? -19.278 -1.232 0.656 1.00 37.57 ? 802 HOH A O 1 HETATM 6862 O O . HOH AA 7 . ? -3.077 -7.103 11.704 1.00 29.25 ? 803 HOH A O 1 HETATM 6863 O O . HOH AA 7 . ? 14.848 -21.412 -8.453 1.00 50.00 ? 804 HOH A O 1 HETATM 6864 O O . HOH AA 7 . ? 16.745 12.898 -7.594 1.00 36.27 ? 805 HOH A O 1 HETATM 6865 O O . HOH AA 7 . ? 21.805 -0.853 10.986 1.00 39.38 ? 806 HOH A O 1 HETATM 6866 O O . HOH AA 7 . ? -13.821 -6.063 -15.998 1.00 37.26 ? 807 HOH A O 1 HETATM 6867 O O . HOH AA 7 . ? 6.388 -6.529 12.101 1.00 30.94 ? 808 HOH A O 1 HETATM 6868 O O . HOH AA 7 . ? 9.606 19.103 -16.260 1.00 46.02 ? 809 HOH A O 1 HETATM 6869 O O . HOH AA 7 . ? -17.257 -15.704 0.508 1.00 34.48 ? 810 HOH A O 1 HETATM 6870 O O . HOH AA 7 . ? -16.967 4.029 -15.409 1.00 44.44 ? 811 HOH A O 1 HETATM 6871 O O . HOH AA 7 . ? -22.887 4.728 -6.165 1.00 38.94 ? 812 HOH A O 1 HETATM 6872 O O . HOH AA 7 . ? 19.660 -1.324 2.287 1.00 37.22 ? 813 HOH A O 1 HETATM 6873 O O . HOH AA 7 . ? 11.272 18.260 19.853 1.00 42.78 ? 814 HOH A O 1 HETATM 6874 O O . HOH AA 7 . ? -18.420 11.172 -12.137 1.00 34.63 ? 815 HOH A O 1 HETATM 6875 O O . HOH AA 7 . ? 3.160 -23.745 5.898 1.00 49.14 ? 816 HOH A O 1 HETATM 6876 O O . HOH AA 7 . ? 10.039 21.741 -13.624 1.00 50.85 ? 817 HOH A O 1 HETATM 6877 O O . HOH AA 7 . ? -3.198 -25.581 4.173 1.00 32.07 ? 818 HOH A O 1 HETATM 6878 O O . HOH AA 7 . ? 2.701 -1.339 16.560 1.00 35.23 ? 819 HOH A O 1 HETATM 6879 O O . HOH AA 7 . ? 3.409 -27.084 -7.688 1.00 37.95 ? 820 HOH A O 1 HETATM 6880 O O . HOH AA 7 . ? -15.987 -20.520 3.185 1.00 41.53 ? 821 HOH A O 1 HETATM 6881 O O . HOH AA 7 . ? -11.565 6.073 16.831 1.00 28.51 ? 822 HOH A O 1 HETATM 6882 O O . HOH AA 7 . ? -16.678 -13.955 7.908 1.00 37.83 ? 823 HOH A O 1 HETATM 6883 O O . HOH AA 7 . ? -22.024 -5.614 -2.016 1.00 54.96 ? 824 HOH A O 1 HETATM 6884 O O . HOH AA 7 . ? 0.744 -9.115 16.387 1.00 41.29 ? 825 HOH A O 1 HETATM 6885 O O . HOH AA 7 . ? 11.129 -22.695 1.972 1.00 39.72 ? 826 HOH A O 1 HETATM 6886 O O . HOH AA 7 . ? -18.461 5.579 11.362 1.00 43.30 ? 827 HOH A O 1 HETATM 6887 O O . HOH AA 7 . ? 18.746 0.099 12.456 1.00 40.42 ? 828 HOH A O 1 HETATM 6888 O O . HOH AA 7 . ? -3.079 -4.947 13.067 1.00 46.89 ? 829 HOH A O 1 HETATM 6889 O O . HOH AA 7 . ? -11.822 8.693 -13.694 1.00 41.69 ? 830 HOH A O 1 HETATM 6890 O O . HOH AA 7 . ? -16.747 16.682 -4.942 1.00 31.20 ? 831 HOH A O 1 HETATM 6891 O O . HOH AA 7 . ? -13.992 18.048 -6.775 1.00 38.80 ? 832 HOH A O 1 HETATM 6892 O O . HOH AA 7 . ? -5.467 -5.674 -14.540 1.00 40.90 ? 833 HOH A O 1 HETATM 6893 O O . HOH AA 7 . ? -18.525 -11.021 5.085 1.00 38.27 ? 834 HOH A O 1 HETATM 6894 O O . HOH AA 7 . ? 14.230 14.131 -10.440 1.00 33.19 ? 835 HOH A O 1 HETATM 6895 O O . HOH AA 7 . ? -5.737 1.709 22.333 1.00 40.40 ? 836 HOH A O 1 HETATM 6896 O O . HOH AA 7 . ? -9.517 2.220 18.875 1.00 49.51 ? 837 HOH A O 1 HETATM 6897 O O . HOH AA 7 . ? -19.115 -23.868 -3.493 1.00 44.53 ? 838 HOH A O 1 HETATM 6898 O O . HOH AA 7 . ? 5.363 -17.145 6.248 1.00 28.01 ? 839 HOH A O 1 HETATM 6899 O O . HOH AA 7 . ? 4.401 -14.118 11.651 1.00 41.90 ? 840 HOH A O 1 HETATM 6900 O O . HOH AA 7 . ? 17.283 -7.808 -17.176 1.00 48.56 ? 841 HOH A O 1 HETATM 6901 O O . HOH AA 7 . ? -19.608 0.762 6.142 1.00 45.41 ? 842 HOH A O 1 HETATM 6902 O O . HOH AA 7 . ? 0.819 -29.212 3.723 1.00 46.78 ? 843 HOH A O 1 HETATM 6903 O O . HOH AA 7 . ? 19.419 1.661 -11.990 1.00 44.10 ? 844 HOH A O 1 HETATM 6904 O O . HOH AA 7 . ? 8.965 4.838 -14.252 1.00 39.25 ? 845 HOH A O 1 HETATM 6905 O O . HOH AA 7 . ? 17.278 -5.393 -17.657 1.00 56.85 ? 846 HOH A O 1 HETATM 6906 O O . HOH AA 7 . ? 21.971 15.231 6.903 1.00 43.48 ? 847 HOH A O 1 HETATM 6907 O O . HOH AA 7 . ? -7.605 -10.856 -12.938 1.00 44.49 ? 848 HOH A O 1 HETATM 6908 O O . HOH AA 7 . ? -3.688 -4.702 15.734 1.00 40.73 ? 849 HOH A O 1 HETATM 6909 O O . HOH AA 7 . ? -17.324 2.202 -13.951 1.00 43.12 ? 850 HOH A O 1 HETATM 6910 O O . HOH AA 7 . ? 18.544 -8.442 -14.128 1.00 54.79 ? 851 HOH A O 1 HETATM 6911 O O . HOH AA 7 . ? 1.657 9.060 -15.481 1.00 41.86 ? 852 HOH A O 1 HETATM 6912 O O . HOH AA 7 . ? 14.642 5.727 -13.800 1.00 47.77 ? 853 HOH A O 1 HETATM 6913 O O . HOH AA 7 . ? -18.160 -23.332 3.404 1.00 53.39 ? 854 HOH A O 1 HETATM 6914 O O . HOH AA 7 . ? 17.926 -17.205 -13.280 1.00 53.63 ? 855 HOH A O 1 HETATM 6915 O O . HOH AA 7 . ? 10.749 -1.146 -15.493 1.00 44.26 ? 856 HOH A O 1 HETATM 6916 O O . HOH AA 7 . ? -5.290 2.621 -14.913 1.00 44.11 ? 857 HOH A O 1 HETATM 6917 O O . HOH AA 7 . ? 16.048 -20.367 -6.422 1.00 49.58 ? 858 HOH A O 1 HETATM 6918 O O . HOH AA 7 . ? -5.815 23.349 -10.861 1.00 53.88 ? 859 HOH A O 1 HETATM 6919 O O . HOH AA 7 . ? -18.305 15.376 -7.425 1.00 42.48 ? 860 HOH A O 1 HETATM 6920 O O . HOH AA 7 . ? 5.647 -5.801 -10.776 1.00 37.40 ? 861 HOH A O 1 HETATM 6921 O O . HOH AA 7 . ? -0.342 12.240 -16.618 1.00 53.14 ? 862 HOH A O 1 HETATM 6922 O O . HOH AA 7 . ? -16.825 18.432 -1.914 1.00 39.74 ? 863 HOH A O 1 HETATM 6923 O O . HOH AA 7 . ? -19.853 -2.121 3.591 1.00 44.23 ? 864 HOH A O 1 HETATM 6924 O O . HOH AA 7 . ? 19.524 11.433 -7.906 1.00 38.38 ? 865 HOH A O 1 HETATM 6925 O O . HOH AA 7 . ? -22.396 2.322 1.217 1.00 46.70 ? 866 HOH A O 1 HETATM 6926 O O . HOH AA 7 . ? -20.422 -5.801 4.901 1.00 51.59 ? 867 HOH A O 1 HETATM 6927 O O . HOH AA 7 . ? 6.202 -3.466 -10.733 1.00 40.89 ? 868 HOH A O 1 HETATM 6928 O O . HOH AA 7 . ? 12.698 -16.472 2.109 1.00 35.59 ? 869 HOH A O 1 HETATM 6929 O O . HOH AA 7 . ? -17.748 -22.086 -2.007 1.00 31.95 ? 870 HOH A O 1 HETATM 6930 O O . HOH AA 7 . ? 0.256 -7.177 -8.232 1.00 38.79 ? 871 HOH A O 1 HETATM 6931 O O . HOH AA 7 . ? -18.637 18.169 -0.637 1.00 44.99 ? 872 HOH A O 1 HETATM 6932 O O . HOH AA 7 . ? -21.730 0.664 -0.055 1.00 39.09 ? 873 HOH A O 1 HETATM 6933 O O . HOH AA 7 . ? -14.103 4.230 17.902 1.00 47.80 ? 874 HOH A O 1 HETATM 6934 O O . HOH AA 7 . ? -12.937 -5.256 20.030 1.00 55.76 ? 875 HOH A O 1 HETATM 6935 O O . HOH AA 7 . ? -9.576 12.763 -16.340 1.00 39.44 ? 876 HOH A O 1 HETATM 6936 O O . HOH AA 7 . ? -13.608 21.659 -5.694 1.00 43.00 ? 877 HOH A O 1 HETATM 6937 O O . HOH AA 7 . ? -7.147 14.493 17.219 1.00 50.67 ? 878 HOH A O 1 HETATM 6938 O O . HOH AA 7 . ? -17.847 -17.671 2.234 1.00 43.51 ? 879 HOH A O 1 HETATM 6939 O O . HOH AA 7 . ? 7.469 10.350 -18.589 1.00 47.57 ? 880 HOH A O 1 HETATM 6940 O O . HOH AA 7 . ? -8.657 27.931 -4.198 1.00 35.89 ? 881 HOH A O 1 HETATM 6941 O O . HOH AA 7 . ? 16.311 -1.441 10.588 1.00 42.49 ? 882 HOH A O 1 HETATM 6942 O O . HOH AA 7 . ? -11.223 24.838 -4.721 1.00 32.58 ? 883 HOH A O 1 HETATM 6943 O O . HOH AA 7 . ? 10.406 21.058 7.887 1.00 35.01 ? 884 HOH A O 1 HETATM 6944 O O . HOH AA 7 . ? -7.032 20.866 16.433 1.00 49.38 ? 885 HOH A O 1 HETATM 6945 O O . HOH AA 7 . ? 20.940 2.484 0.372 1.00 46.56 ? 886 HOH A O 1 HETATM 6946 O O . HOH AA 7 . ? 18.955 0.188 -13.852 1.00 49.83 ? 887 HOH A O 1 HETATM 6947 O O . HOH AA 7 . ? 19.096 9.893 -9.421 1.00 45.10 ? 888 HOH A O 1 HETATM 6948 O O . HOH AA 7 . ? 11.524 5.484 -14.967 1.00 42.37 ? 889 HOH A O 1 HETATM 6949 O O . HOH AA 7 . ? -7.375 12.257 17.825 1.00 48.00 ? 890 HOH A O 1 HETATM 6950 O O . HOH AA 7 . ? -10.276 -3.988 -19.150 1.00 44.78 ? 891 HOH A O 1 HETATM 6951 O O . HOH AA 7 . ? 17.940 -3.338 10.320 1.00 50.63 ? 892 HOH A O 1 HETATM 6952 O O . HOH AA 7 . ? -15.476 17.028 -8.892 1.00 37.42 ? 893 HOH A O 1 HETATM 6953 O O . HOH AA 7 . ? 9.910 2.266 -13.688 1.00 48.42 ? 894 HOH A O 1 HETATM 6954 O O . HOH AA 7 . ? -11.790 24.587 -7.069 1.00 44.16 ? 895 HOH A O 1 HETATM 6955 O O . HOH BA 7 . ? 27.261 -1.123 17.845 1.00 51.57 ? 601 HOH B O 1 HETATM 6956 O O . HOH BA 7 . ? 40.797 -9.505 37.118 1.00 60.65 ? 602 HOH B O 1 HETATM 6957 O O . HOH BA 7 . ? 23.491 -21.111 24.034 1.00 30.89 ? 603 HOH B O 1 HETATM 6958 O O . HOH BA 7 . ? -9.546 -3.233 28.739 1.00 46.22 ? 604 HOH B O 1 HETATM 6959 O O . HOH BA 7 . ? 15.836 0.239 51.875 1.00 47.23 ? 605 HOH B O 1 HETATM 6960 O O . HOH BA 7 . ? -4.669 -3.653 42.485 1.00 45.14 ? 606 HOH B O 1 HETATM 6961 O O . HOH BA 7 . ? 3.116 -15.216 52.743 1.00 40.51 ? 607 HOH B O 1 HETATM 6962 O O . HOH BA 7 . ? 5.432 -14.111 55.077 1.00 45.35 ? 608 HOH B O 1 HETATM 6963 O O . HOH BA 7 . ? 26.950 -2.403 21.059 1.00 42.33 ? 609 HOH B O 1 HETATM 6964 O O . HOH BA 7 . ? 25.622 -8.382 15.837 1.00 31.77 ? 610 HOH B O 1 HETATM 6965 O O . HOH BA 7 . ? 10.185 -10.993 18.019 1.00 31.36 ? 611 HOH B O 1 HETATM 6966 O O . HOH BA 7 . ? 13.338 -10.403 26.908 1.00 24.99 ? 612 HOH B O 1 HETATM 6967 O O . HOH BA 7 . ? 34.075 -10.017 41.008 1.00 40.22 ? 613 HOH B O 1 HETATM 6968 O O . HOH BA 7 . ? 4.623 -33.830 31.569 1.00 37.03 ? 614 HOH B O 1 HETATM 6969 O O . HOH BA 7 . ? 30.838 -5.133 23.991 1.00 48.23 ? 615 HOH B O 1 HETATM 6970 O O . HOH BA 7 . ? -7.628 -16.760 17.904 1.00 51.47 ? 616 HOH B O 1 HETATM 6971 O O . HOH BA 7 . ? 33.533 -9.449 32.018 1.00 46.52 ? 617 HOH B O 1 HETATM 6972 O O . HOH BA 7 . ? 30.383 -16.897 14.744 1.00 37.64 ? 618 HOH B O 1 HETATM 6973 O O . HOH BA 7 . ? 1.642 -22.398 18.076 1.00 48.95 ? 619 HOH B O 1 HETATM 6974 O O . HOH BA 7 . ? -2.111 -5.765 23.301 1.00 44.89 ? 620 HOH B O 1 HETATM 6975 O O . HOH BA 7 . ? 30.760 -3.490 42.611 1.00 45.41 ? 621 HOH B O 1 HETATM 6976 O O . HOH BA 7 . ? 20.247 -5.650 52.353 1.00 34.43 ? 622 HOH B O 1 HETATM 6977 O O . HOH BA 7 . ? 17.349 -0.580 56.949 1.00 52.25 ? 623 HOH B O 1 HETATM 6978 O O . HOH BA 7 . ? 26.459 1.152 40.828 1.00 43.11 ? 624 HOH B O 1 HETATM 6979 O O . HOH BA 7 . ? 8.041 -23.440 14.068 1.00 37.28 ? 625 HOH B O 1 HETATM 6980 O O . HOH BA 7 . ? 3.258 12.382 35.727 1.00 56.23 ? 626 HOH B O 1 HETATM 6981 O O . HOH BA 7 . ? 40.188 -11.001 35.343 1.00 50.84 ? 627 HOH B O 1 HETATM 6982 O O . HOH BA 7 . ? 33.087 -7.343 23.882 1.00 39.02 ? 628 HOH B O 1 HETATM 6983 O O . HOH BA 7 . ? 22.666 -29.285 29.689 1.00 52.05 ? 629 HOH B O 1 HETATM 6984 O O . HOH BA 7 . ? 10.344 -14.199 51.661 1.00 38.14 ? 630 HOH B O 1 HETATM 6985 O O . HOH BA 7 . ? 15.833 -9.029 55.711 1.00 41.42 ? 631 HOH B O 1 HETATM 6986 O O . HOH BA 7 . ? 17.317 0.450 21.187 1.00 44.33 ? 632 HOH B O 1 HETATM 6987 O O . HOH BA 7 . ? 3.889 3.458 25.605 1.00 34.88 ? 633 HOH B O 1 HETATM 6988 O O . HOH BA 7 . ? 4.471 -5.941 14.103 1.00 34.33 ? 634 HOH B O 1 HETATM 6989 O O . HOH BA 7 . ? 22.068 -1.559 36.771 1.00 25.47 ? 635 HOH B O 1 HETATM 6990 O O . HOH BA 7 . ? 13.035 -29.285 14.407 1.00 40.92 ? 636 HOH B O 1 HETATM 6991 O O . HOH BA 7 . ? 6.573 -31.593 31.231 1.00 36.56 ? 637 HOH B O 1 HETATM 6992 O O . HOH BA 7 . ? 7.132 -16.744 13.815 1.00 28.18 ? 638 HOH B O 1 HETATM 6993 O O . HOH BA 7 . ? 8.369 -20.473 47.027 1.00 28.44 ? 639 HOH B O 1 HETATM 6994 O O . HOH BA 7 . ? 22.848 -0.508 32.315 1.00 25.21 ? 640 HOH B O 1 HETATM 6995 O O . HOH BA 7 . ? 13.872 -24.207 42.153 1.00 30.74 ? 641 HOH B O 1 HETATM 6996 O O . HOH BA 7 . ? -5.328 2.486 47.002 1.00 49.28 ? 642 HOH B O 1 HETATM 6997 O O . HOH BA 7 . ? 16.049 -3.763 29.807 1.00 20.35 ? 643 HOH B O 1 HETATM 6998 O O . HOH BA 7 . ? -1.004 -15.165 16.893 1.00 40.66 ? 644 HOH B O 1 HETATM 6999 O O . HOH BA 7 . ? -6.725 -12.100 50.716 1.00 33.87 ? 645 HOH B O 1 HETATM 7000 O O . HOH BA 7 . ? 24.844 -17.695 21.328 1.00 34.65 ? 646 HOH B O 1 HETATM 7001 O O . HOH BA 7 . ? 18.958 -18.632 41.506 1.00 26.20 ? 647 HOH B O 1 HETATM 7002 O O . HOH BA 7 . ? 16.319 0.668 29.280 1.00 23.80 ? 648 HOH B O 1 HETATM 7003 O O . HOH BA 7 . ? 23.451 -14.631 46.363 1.00 25.26 ? 649 HOH B O 1 HETATM 7004 O O . HOH BA 7 . ? 5.157 -27.834 45.113 1.00 36.16 ? 650 HOH B O 1 HETATM 7005 O O . HOH BA 7 . ? 15.925 -6.539 54.855 1.00 33.13 ? 651 HOH B O 1 HETATM 7006 O O . HOH BA 7 . ? 18.566 4.827 27.458 1.00 35.24 ? 652 HOH B O 1 HETATM 7007 O O . HOH BA 7 . ? -9.299 -20.871 46.772 1.00 28.87 ? 653 HOH B O 1 HETATM 7008 O O . HOH BA 7 . ? 8.049 -22.592 37.308 1.00 25.71 ? 654 HOH B O 1 HETATM 7009 O O . HOH BA 7 . ? 23.357 -19.748 47.168 1.00 41.40 ? 655 HOH B O 1 HETATM 7010 O O . HOH BA 7 . ? 19.599 -8.245 19.850 1.00 28.15 ? 656 HOH B O 1 HETATM 7011 O O . HOH BA 7 . ? 28.646 -17.763 19.220 1.00 37.65 ? 657 HOH B O 1 HETATM 7012 O O . HOH BA 7 . ? 5.565 1.619 24.225 1.00 32.42 ? 658 HOH B O 1 HETATM 7013 O O . HOH BA 7 . ? -7.600 -18.122 36.176 1.00 34.53 ? 659 HOH B O 1 HETATM 7014 O O . HOH BA 7 . ? 23.480 -11.812 42.364 1.00 22.65 ? 660 HOH B O 1 HETATM 7015 O O . HOH BA 7 . ? 29.432 -16.468 42.554 1.00 29.45 ? 661 HOH B O 1 HETATM 7016 O O . HOH BA 7 . ? 31.542 -11.129 31.383 1.00 32.11 ? 662 HOH B O 1 HETATM 7017 O O . HOH BA 7 . ? 16.453 -23.113 46.710 1.00 37.26 ? 663 HOH B O 1 HETATM 7018 O O . HOH BA 7 . ? 36.662 -17.979 21.067 1.00 52.00 ? 664 HOH B O 1 HETATM 7019 O O . HOH BA 7 . ? 30.214 -12.364 25.292 1.00 29.70 ? 665 HOH B O 1 HETATM 7020 O O . HOH BA 7 . ? 8.913 -18.482 48.856 1.00 33.24 ? 666 HOH B O 1 HETATM 7021 O O . HOH BA 7 . ? 1.427 -9.540 24.090 1.00 24.73 ? 667 HOH B O 1 HETATM 7022 O O . HOH BA 7 . ? 33.305 -11.111 48.754 1.00 31.27 ? 668 HOH B O 1 HETATM 7023 O O . HOH BA 7 . ? 11.225 -23.723 47.266 1.00 33.36 ? 669 HOH B O 1 HETATM 7024 O O . HOH BA 7 . ? 28.876 -10.611 31.932 1.00 26.94 ? 670 HOH B O 1 HETATM 7025 O O . HOH BA 7 . ? -5.101 -5.465 24.073 1.00 49.65 ? 671 HOH B O 1 HETATM 7026 O O . HOH BA 7 . ? 14.909 -6.216 20.692 1.00 31.27 ? 672 HOH B O 1 HETATM 7027 O O . HOH BA 7 . ? 4.914 -28.798 18.165 1.00 41.43 ? 673 HOH B O 1 HETATM 7028 O O . HOH BA 7 . ? 5.115 -34.185 23.312 1.00 45.52 ? 674 HOH B O 1 HETATM 7029 O O . HOH BA 7 . ? 7.593 9.340 37.935 1.00 42.83 ? 675 HOH B O 1 HETATM 7030 O O . HOH BA 7 . ? 21.894 -9.303 21.756 1.00 30.08 ? 676 HOH B O 1 HETATM 7031 O O . HOH BA 7 . ? -0.563 -1.384 43.507 1.00 32.22 ? 677 HOH B O 1 HETATM 7032 O O . HOH BA 7 . ? 18.768 -24.261 22.428 1.00 32.18 ? 678 HOH B O 1 HETATM 7033 O O . HOH BA 7 . ? 34.556 -17.901 23.432 1.00 44.38 ? 679 HOH B O 1 HETATM 7034 O O . HOH BA 7 . ? 5.830 -21.426 26.079 1.00 25.63 ? 680 HOH B O 1 HETATM 7035 O O . HOH BA 7 . ? -10.136 -17.853 25.352 1.00 44.40 ? 681 HOH B O 1 HETATM 7036 O O . HOH BA 7 . ? -1.304 -3.858 23.911 1.00 37.41 ? 682 HOH B O 1 HETATM 7037 O O . HOH BA 7 . ? 12.390 -24.927 30.633 1.00 42.65 ? 683 HOH B O 1 HETATM 7038 O O . HOH BA 7 . ? 22.028 -13.388 48.954 1.00 30.79 ? 684 HOH B O 1 HETATM 7039 O O . HOH BA 7 . ? 2.466 -22.664 35.421 1.00 26.45 ? 685 HOH B O 1 HETATM 7040 O O . HOH BA 7 . ? 16.017 -27.242 35.207 1.00 31.74 ? 686 HOH B O 1 HETATM 7041 O O . HOH BA 7 . ? 0.776 -12.101 55.471 1.00 45.32 ? 687 HOH B O 1 HETATM 7042 O O . HOH BA 7 . ? 2.667 -7.810 26.254 1.00 22.17 ? 688 HOH B O 1 HETATM 7043 O O . HOH BA 7 . ? -1.411 -25.995 39.170 1.00 38.80 ? 689 HOH B O 1 HETATM 7044 O O . HOH BA 7 . ? 31.109 -3.627 26.372 1.00 51.51 ? 690 HOH B O 1 HETATM 7045 O O . HOH BA 7 . ? 30.834 -18.810 24.353 1.00 37.40 ? 691 HOH B O 1 HETATM 7046 O O . HOH BA 7 . ? -11.233 -8.205 50.483 1.00 32.06 ? 692 HOH B O 1 HETATM 7047 O O . HOH BA 7 . ? -3.870 -2.393 28.900 1.00 28.25 ? 693 HOH B O 1 HETATM 7048 O O . HOH BA 7 . ? 28.412 -19.823 23.070 1.00 36.74 ? 694 HOH B O 1 HETATM 7049 O O . HOH BA 7 . ? 22.651 5.003 39.861 1.00 37.60 ? 695 HOH B O 1 HETATM 7050 O O . HOH BA 7 . ? 24.227 2.082 43.093 1.00 36.04 ? 696 HOH B O 1 HETATM 7051 O O . HOH BA 7 . ? 32.726 -8.470 47.986 1.00 31.77 ? 697 HOH B O 1 HETATM 7052 O O . HOH BA 7 . ? 0.234 -28.340 32.266 1.00 45.35 ? 698 HOH B O 1 HETATM 7053 O O . HOH BA 7 . ? 7.483 6.106 21.138 1.00 32.40 ? 699 HOH B O 1 HETATM 7054 O O . HOH BA 7 . ? 7.693 5.401 42.094 1.00 41.31 ? 700 HOH B O 1 HETATM 7055 O O . HOH BA 7 . ? 21.811 -21.746 3.920 1.00 52.33 ? 701 HOH B O 1 HETATM 7056 O O . HOH BA 7 . ? -8.782 -11.046 38.163 1.00 43.23 ? 702 HOH B O 1 HETATM 7057 O O . HOH BA 7 . ? 6.365 6.577 24.477 1.00 39.48 ? 703 HOH B O 1 HETATM 7058 O O . HOH BA 7 . ? 29.642 -0.862 31.975 1.00 40.95 ? 704 HOH B O 1 HETATM 7059 O O . HOH BA 7 . ? 21.679 -13.897 32.788 1.00 21.18 ? 705 HOH B O 1 HETATM 7060 O O . HOH BA 7 . ? 20.227 -13.050 35.289 1.00 20.89 ? 706 HOH B O 1 HETATM 7061 O O . HOH BA 7 . ? 35.999 -15.350 37.868 1.00 31.03 ? 707 HOH B O 1 HETATM 7062 O O . HOH BA 7 . ? 29.551 -12.268 49.105 1.00 35.88 ? 708 HOH B O 1 HETATM 7063 O O . HOH BA 7 . ? 24.344 4.109 26.074 1.00 40.49 ? 709 HOH B O 1 HETATM 7064 O O . HOH BA 7 . ? 15.282 7.069 37.508 1.00 43.50 ? 710 HOH B O 1 HETATM 7065 O O . HOH BA 7 . ? 21.133 5.107 28.452 1.00 32.99 ? 711 HOH B O 1 HETATM 7066 O O . HOH BA 7 . ? 22.490 7.228 32.772 1.00 51.91 ? 712 HOH B O 1 HETATM 7067 O O . HOH BA 7 . ? 6.984 -19.744 32.739 1.00 22.25 ? 713 HOH B O 1 HETATM 7068 O O . HOH BA 7 . ? 11.641 -0.006 44.694 1.00 41.17 ? 714 HOH B O 1 HETATM 7069 O O . HOH BA 7 . ? -3.070 -18.583 25.456 1.00 31.68 ? 715 HOH B O 1 HETATM 7070 O O . HOH BA 7 . ? 7.998 0.955 41.962 1.00 25.52 ? 716 HOH B O 1 HETATM 7071 O O . HOH BA 7 . ? 16.505 -18.008 13.095 1.00 31.62 ? 717 HOH B O 1 HETATM 7072 O O . HOH BA 7 . ? 17.436 -8.463 14.941 1.00 29.86 ? 718 HOH B O 1 HETATM 7073 O O . HOH BA 7 . ? -4.892 2.461 25.226 1.00 29.80 ? 719 HOH B O 1 HETATM 7074 O O . HOH BA 7 . ? -2.608 -17.731 21.263 1.00 41.39 ? 720 HOH B O 1 HETATM 7075 O O . HOH BA 7 . ? 13.821 1.299 45.710 1.00 45.76 ? 721 HOH B O 1 HETATM 7076 O O . HOH BA 7 . ? 18.414 -11.138 35.232 1.00 22.33 ? 722 HOH B O 1 HETATM 7077 O O . HOH BA 7 . ? 3.144 -15.746 17.756 1.00 34.26 ? 723 HOH B O 1 HETATM 7078 O O . HOH BA 7 . ? 18.382 -12.621 53.925 1.00 33.64 ? 724 HOH B O 1 HETATM 7079 O O . HOH BA 7 . ? 14.952 -26.678 32.807 1.00 44.26 ? 725 HOH B O 1 HETATM 7080 O O . HOH BA 7 . ? 24.941 -22.200 44.476 1.00 40.61 ? 726 HOH B O 1 HETATM 7081 O O . HOH BA 7 . ? 13.383 -30.276 28.667 1.00 43.61 ? 727 HOH B O 1 HETATM 7082 O O . HOH BA 7 . ? 22.335 2.778 22.977 1.00 38.82 ? 728 HOH B O 1 HETATM 7083 O O . HOH BA 7 . ? 13.699 2.541 27.839 1.00 25.44 ? 729 HOH B O 1 HETATM 7084 O O . HOH BA 7 . ? 33.951 -25.531 33.365 1.00 38.33 ? 730 HOH B O 1 HETATM 7085 O O . HOH BA 7 . ? 31.439 -5.320 28.683 1.00 49.88 ? 731 HOH B O 1 HETATM 7086 O O . HOH BA 7 . ? -4.745 -9.512 20.169 1.00 37.57 ? 732 HOH B O 1 HETATM 7087 O O . HOH BA 7 . ? 14.260 8.063 35.163 1.00 45.04 ? 733 HOH B O 1 HETATM 7088 O O . HOH BA 7 . ? -9.891 -7.024 47.340 1.00 47.22 ? 734 HOH B O 1 HETATM 7089 O O . HOH BA 7 . ? 32.105 -10.945 42.437 1.00 32.90 ? 735 HOH B O 1 HETATM 7090 O O . HOH BA 7 . ? 24.655 -6.756 9.059 1.00 42.65 ? 736 HOH B O 1 HETATM 7091 O O . HOH BA 7 . ? 28.264 -18.138 44.452 1.00 32.29 ? 737 HOH B O 1 HETATM 7092 O O . HOH BA 7 . ? 8.949 -32.336 17.396 1.00 40.79 ? 738 HOH B O 1 HETATM 7093 O O . HOH BA 7 . ? 16.386 -5.814 23.041 1.00 29.42 ? 739 HOH B O 1 HETATM 7094 O O . HOH BA 7 . ? 7.961 -19.745 40.541 1.00 28.41 ? 740 HOH B O 1 HETATM 7095 O O . HOH BA 7 . ? 21.426 -24.754 41.680 1.00 49.92 ? 741 HOH B O 1 HETATM 7096 O O . HOH BA 7 . ? 10.946 1.552 49.524 1.00 40.45 ? 742 HOH B O 1 HETATM 7097 O O . HOH BA 7 . ? 8.158 3.264 49.185 1.00 44.99 ? 743 HOH B O 1 HETATM 7098 O O . HOH BA 7 . ? 20.455 -22.603 20.837 1.00 33.73 ? 744 HOH B O 1 HETATM 7099 O O . HOH BA 7 . ? 9.918 -1.963 19.728 1.00 32.96 ? 745 HOH B O 1 HETATM 7100 O O . HOH BA 7 . ? -4.120 -1.844 49.506 1.00 38.18 ? 746 HOH B O 1 HETATM 7101 O O . HOH BA 7 . ? 30.061 -5.152 12.025 1.00 46.06 ? 747 HOH B O 1 HETATM 7102 O O . HOH BA 7 . ? -10.935 -11.656 17.249 1.00 38.58 ? 748 HOH B O 1 HETATM 7103 O O . HOH BA 7 . ? 19.509 -23.437 25.091 1.00 36.05 ? 749 HOH B O 1 HETATM 7104 O O . HOH BA 7 . ? 32.919 -14.805 47.262 1.00 41.52 ? 750 HOH B O 1 HETATM 7105 O O . HOH BA 7 . ? 32.465 -26.518 36.942 1.00 36.99 ? 751 HOH B O 1 HETATM 7106 O O . HOH BA 7 . ? 24.817 -1.974 33.361 1.00 31.69 ? 752 HOH B O 1 HETATM 7107 O O . HOH BA 7 . ? 20.305 7.135 41.872 1.00 44.90 ? 753 HOH B O 1 HETATM 7108 O O . HOH BA 7 . ? 29.198 -6.675 49.060 1.00 37.63 ? 754 HOH B O 1 HETATM 7109 O O . HOH BA 7 . ? -14.844 -13.002 28.876 1.00 48.62 ? 755 HOH B O 1 HETATM 7110 O O . HOH BA 7 . ? -0.638 -32.386 23.748 1.00 45.36 ? 756 HOH B O 1 HETATM 7111 O O . HOH BA 7 . ? 2.960 -27.270 39.433 1.00 34.75 ? 757 HOH B O 1 HETATM 7112 O O . HOH BA 7 . ? 7.469 -13.452 11.837 1.00 31.74 ? 758 HOH B O 1 HETATM 7113 O O . HOH BA 7 . ? 18.509 -21.026 48.423 1.00 37.82 ? 759 HOH B O 1 HETATM 7114 O O . HOH BA 7 . ? -1.849 0.946 36.729 1.00 30.32 ? 760 HOH B O 1 HETATM 7115 O O . HOH BA 7 . ? -4.023 -25.596 35.443 1.00 42.82 ? 761 HOH B O 1 HETATM 7116 O O . HOH BA 7 . ? 17.785 -19.338 50.559 1.00 42.13 ? 762 HOH B O 1 HETATM 7117 O O . HOH BA 7 . ? -4.571 6.184 33.298 1.00 33.73 ? 763 HOH B O 1 HETATM 7118 O O . HOH BA 7 . ? 21.237 4.695 24.190 1.00 52.86 ? 764 HOH B O 1 HETATM 7119 O O . HOH BA 7 . ? 6.308 -20.483 51.494 1.00 48.10 ? 765 HOH B O 1 HETATM 7120 O O . HOH BA 7 . ? -3.733 -8.407 23.485 1.00 37.74 ? 766 HOH B O 1 HETATM 7121 O O . HOH BA 7 . ? 7.166 -23.012 48.171 1.00 37.99 ? 767 HOH B O 1 HETATM 7122 O O . HOH BA 7 . ? 11.419 -25.065 6.368 1.00 53.66 ? 768 HOH B O 1 HETATM 7123 O O . HOH BA 7 . ? -12.859 -15.272 32.498 1.00 40.11 ? 769 HOH B O 1 HETATM 7124 O O . HOH BA 7 . ? 21.385 -10.281 53.990 1.00 43.59 ? 770 HOH B O 1 HETATM 7125 O O . HOH BA 7 . ? 28.189 -37.932 5.324 1.00 53.23 ? 771 HOH B O 1 HETATM 7126 O O . HOH BA 7 . ? 2.900 -24.734 50.810 1.00 44.55 ? 772 HOH B O 1 HETATM 7127 O O . HOH BA 7 . ? -4.678 -4.300 55.533 1.00 43.36 ? 773 HOH B O 1 HETATM 7128 O O . HOH BA 7 . ? 25.915 -19.939 45.285 1.00 42.28 ? 774 HOH B O 1 HETATM 7129 O O . HOH BA 7 . ? 21.863 -5.851 10.100 1.00 35.16 ? 775 HOH B O 1 HETATM 7130 O O . HOH BA 7 . ? 10.732 -18.130 50.464 1.00 40.79 ? 776 HOH B O 1 HETATM 7131 O O . HOH BA 7 . ? 15.080 8.106 24.169 1.00 41.21 ? 777 HOH B O 1 HETATM 7132 O O . HOH BA 7 . ? -3.322 -19.421 23.170 1.00 39.88 ? 778 HOH B O 1 HETATM 7133 O O . HOH BA 7 . ? 9.056 -9.093 16.704 1.00 33.79 ? 779 HOH B O 1 HETATM 7134 O O . HOH BA 7 . ? 26.556 -7.693 49.075 1.00 28.90 ? 780 HOH B O 1 HETATM 7135 O O . HOH BA 7 . ? 25.365 -20.387 21.510 1.00 34.48 ? 781 HOH B O 1 HETATM 7136 O O . HOH BA 7 . ? -5.968 -16.096 50.033 1.00 30.54 ? 782 HOH B O 1 HETATM 7137 O O . HOH BA 7 . ? 29.378 -28.968 38.745 1.00 34.52 ? 783 HOH B O 1 HETATM 7138 O O . HOH BA 7 . ? 1.372 -32.381 22.498 1.00 44.30 ? 784 HOH B O 1 HETATM 7139 O O . HOH BA 7 . ? 26.519 -28.137 24.882 1.00 37.50 ? 785 HOH B O 1 HETATM 7140 O O . HOH BA 7 . ? 15.339 -4.901 56.754 1.00 40.86 ? 786 HOH B O 1 HETATM 7141 O O . HOH BA 7 . ? 1.706 11.156 31.550 1.00 46.25 ? 787 HOH B O 1 HETATM 7142 O O . HOH BA 7 . ? 3.367 -14.104 19.486 1.00 32.22 ? 788 HOH B O 1 HETATM 7143 O O . HOH BA 7 . ? 2.024 -27.106 42.011 1.00 33.66 ? 789 HOH B O 1 HETATM 7144 O O . HOH BA 7 . ? 23.883 -9.609 50.693 1.00 39.45 ? 790 HOH B O 1 HETATM 7145 O O . HOH BA 7 . ? 16.040 6.681 21.565 1.00 40.83 ? 791 HOH B O 1 HETATM 7146 O O . HOH BA 7 . ? 7.747 -28.402 38.399 1.00 40.43 ? 792 HOH B O 1 HETATM 7147 O O . HOH BA 7 . ? 2.232 -10.962 18.733 1.00 31.08 ? 793 HOH B O 1 HETATM 7148 O O . HOH BA 7 . ? 0.318 11.572 29.875 1.00 49.62 ? 794 HOH B O 1 HETATM 7149 O O . HOH BA 7 . ? 30.982 -15.680 48.353 1.00 39.62 ? 795 HOH B O 1 HETATM 7150 O O . HOH BA 7 . ? 8.280 -23.446 11.239 1.00 42.36 ? 796 HOH B O 1 HETATM 7151 O O . HOH BA 7 . ? -2.634 -3.663 56.721 1.00 44.88 ? 797 HOH B O 1 HETATM 7152 O O . HOH BA 7 . ? -6.619 0.805 38.730 1.00 47.37 ? 798 HOH B O 1 HETATM 7153 O O . HOH BA 7 . ? -5.341 -19.832 27.020 1.00 47.80 ? 799 HOH B O 1 HETATM 7154 O O . HOH BA 7 . ? 8.325 11.233 37.129 1.00 54.05 ? 800 HOH B O 1 HETATM 7155 O O . HOH BA 7 . ? 18.718 -20.591 4.920 1.00 53.21 ? 801 HOH B O 1 HETATM 7156 O O . HOH BA 7 . ? -9.260 -6.969 27.477 1.00 47.56 ? 802 HOH B O 1 HETATM 7157 O O . HOH BA 7 . ? -10.348 -17.911 42.174 1.00 42.61 ? 803 HOH B O 1 HETATM 7158 O O . HOH BA 7 . ? 5.841 7.996 36.833 1.00 50.28 ? 804 HOH B O 1 HETATM 7159 O O . HOH BA 7 . ? 16.225 -12.750 55.501 1.00 48.43 ? 805 HOH B O 1 HETATM 7160 O O . HOH BA 7 . ? -9.501 -10.705 42.644 1.00 49.72 ? 806 HOH B O 1 HETATM 7161 O O . HOH BA 7 . ? -2.320 -2.939 41.782 1.00 42.70 ? 807 HOH B O 1 HETATM 7162 O O . HOH BA 7 . ? 10.558 -26.269 47.426 1.00 47.14 ? 808 HOH B O 1 HETATM 7163 O O . HOH BA 7 . ? 1.450 -28.766 37.901 1.00 48.15 ? 809 HOH B O 1 HETATM 7164 O O . HOH BA 7 . ? 13.914 -28.171 28.002 1.00 49.64 ? 810 HOH B O 1 HETATM 7165 O O . HOH BA 7 . ? -6.072 4.864 26.592 1.00 49.12 ? 811 HOH B O 1 HETATM 7166 O O . HOH BA 7 . ? 27.711 -28.799 27.152 1.00 44.98 ? 812 HOH B O 1 HETATM 7167 O O . HOH BA 7 . ? -8.197 1.642 40.820 1.00 56.43 ? 813 HOH B O 1 HETATM 7168 O O . HOH BA 7 . ? 23.013 6.441 27.077 1.00 51.10 ? 814 HOH B O 1 HETATM 7169 O O . HOH BA 7 . ? 26.303 -1.076 50.479 1.00 48.94 ? 815 HOH B O 1 HETATM 7170 O O . HOH BA 7 . ? 3.385 -29.244 43.553 1.00 42.72 ? 816 HOH B O 1 HETATM 7171 O O . HOH BA 7 . ? 27.003 -2.655 48.719 1.00 52.64 ? 817 HOH B O 1 HETATM 7172 O O . HOH BA 7 . ? 12.236 -27.437 29.944 1.00 33.21 ? 818 HOH B O 1 HETATM 7173 O O . HOH BA 7 . ? 18.140 -10.548 55.537 1.00 43.73 ? 819 HOH B O 1 HETATM 7174 O O . HOH BA 7 . ? 18.342 -26.700 34.716 1.00 50.00 ? 820 HOH B O 1 HETATM 7175 O O . HOH BA 7 . ? 16.087 -26.190 30.628 1.00 56.31 ? 821 HOH B O 1 HETATM 7176 O O . HOH BA 7 . ? 5.152 -28.936 38.493 1.00 39.99 ? 822 HOH B O 1 HETATM 7177 O O . HOH BA 7 . ? 23.206 -21.249 49.418 1.00 39.02 ? 823 HOH B O 1 HETATM 7178 O O . HOH BA 7 . ? 14.371 -24.036 47.230 1.00 45.68 ? 824 HOH B O 1 HETATM 7179 O O . HOH BA 7 . ? 4.623 -24.174 52.832 1.00 53.15 ? 825 HOH B O 1 HETATM 7180 O O . HOH BA 7 . ? 6.671 -15.477 11.143 1.00 43.06 ? 826 HOH B O 1 HETATM 7181 O O . HOH BA 7 . ? 18.745 -5.817 54.896 1.00 35.69 ? 827 HOH B O 1 HETATM 7182 O O . HOH BA 7 . ? 14.099 11.546 22.748 1.00 49.23 ? 828 HOH B O 1 HETATM 7183 O O . HOH BA 7 . ? 24.878 -8.283 7.549 1.00 43.67 ? 829 HOH B O 1 HETATM 7184 O O . HOH BA 7 . ? -3.289 -14.011 17.588 1.00 43.13 ? 830 HOH B O 1 HETATM 7185 O O . HOH BA 7 . ? -15.058 -16.941 39.209 1.00 53.05 ? 831 HOH B O 1 HETATM 7186 O O . HOH BA 7 . ? -3.385 -24.411 39.563 1.00 47.36 ? 832 HOH B O 1 HETATM 7187 O O . HOH BA 7 . ? 14.735 -14.882 55.583 1.00 55.17 ? 833 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 MET 1 1 ? ? ? A . n A 1 2 ALA 2 2 ? ? ? A . n A 1 3 ALA 3 3 ? ? ? A . n A 1 4 LYS 4 4 ? ? ? A . n A 1 5 LEU 5 5 ? ? ? A . n A 1 6 TRP 6 6 ? ? ? A . n A 1 7 THR 7 7 ? ? ? A . n A 1 8 PHE 8 8 ? ? ? A . n A 1 9 LEU 9 9 ? ? ? A . n A 1 10 LEU 10 10 ? ? ? A . n A 1 11 GLY 11 11 ? ? ? A . n A 1 12 PHE 12 12 ? ? ? A . n A 1 13 GLY 13 13 ? ? ? A . n A 1 14 LEU 14 14 ? ? ? A . n A 1 15 SER 15 15 ? ? ? A . n A 1 16 TRP 16 16 ? ? ? A . n A 1 17 VAL 17 17 ? ? ? A . n A 1 18 TRP 18 18 ? ? ? A . n A 1 19 PRO 19 19 ? ? ? A . n A 1 20 ALA 20 20 ? ? ? A . n A 1 21 SER 21 21 ? ? ? A . n A 1 22 ALA 22 22 ? ? ? A . n A 1 23 HIS 23 23 ? ? ? A . n A 1 24 ARG 24 24 24 ARG ARG A . n A 1 25 LYS 25 25 25 LYS LYS A . n A 1 26 LEU 26 26 26 LEU LEU A . n A 1 27 LEU 27 27 27 LEU LEU A . n A 1 28 VAL 28 28 28 VAL VAL A . n A 1 29 LEU 29 29 29 LEU LEU A . n A 1 30 LEU 30 30 30 LEU LEU A . n A 1 31 LEU 31 31 31 LEU LEU A . n A 1 32 ASP 32 32 32 ASP ASP A . n A 1 33 GLY 33 33 33 GLY GLY A . n A 1 34 PHE 34 34 34 PHE PHE A . n A 1 35 ARG 35 35 35 ARG ARG A . n A 1 36 SER 36 36 36 SER SER A . n A 1 37 ASP 37 37 37 ASP ASP A . n A 1 38 TYR 38 38 38 TYR TYR A . n A 1 39 ILE 39 39 39 ILE ILE A . n A 1 40 SER 40 40 40 SER SER A . n A 1 41 GLU 41 41 41 GLU GLU A . n A 1 42 ASP 42 42 42 ASP ASP A . n A 1 43 ALA 43 43 43 ALA ALA A . n A 1 44 LEU 44 44 44 LEU LEU A . n A 1 45 ALA 45 45 45 ALA ALA A . n A 1 46 SER 46 46 46 SER SER A . n A 1 47 LEU 47 47 47 LEU LEU A . n A 1 48 PRO 48 48 48 PRO PRO A . n A 1 49 GLY 49 49 49 GLY GLY A . n A 1 50 PHE 50 50 50 PHE PHE A . n A 1 51 ARG 51 51 51 ARG ARG A . n A 1 52 GLU 52 52 52 GLU GLU A . n A 1 53 ILE 53 53 53 ILE ILE A . n A 1 54 VAL 54 54 54 VAL VAL A . n A 1 55 ASN 55 55 55 ASN ASN A . n A 1 56 ARG 56 56 56 ARG ARG A . n A 1 57 GLY 57 57 57 GLY GLY A . n A 1 58 VAL 58 58 58 VAL VAL A . n A 1 59 LYS 59 59 59 LYS LYS A . n A 1 60 VAL 60 60 60 VAL VAL A . n A 1 61 ASP 61 61 61 ASP ASP A . n A 1 62 TYR 62 62 62 TYR TYR A . n A 1 63 LEU 63 63 63 LEU LEU A . n A 1 64 THR 64 64 64 THR THR A . n A 1 65 PRO 65 65 65 PRO PRO A . n A 1 66 ASP 66 66 66 ASP ASP A . n A 1 67 PHE 67 67 67 PHE PHE A . n A 1 68 PRO 68 68 68 PRO PRO A . n A 1 69 SER 69 69 69 SER SER A . n A 1 70 LEU 70 70 70 LEU LEU A . n A 1 71 SER 71 71 71 SER SER A . n A 1 72 TYR 72 72 72 TYR TYR A . n A 1 73 PRO 73 73 73 PRO PRO A . n A 1 74 ASN 74 74 74 ASN ASN A . n A 1 75 TYR 75 75 75 TYR TYR A . n A 1 76 TYR 76 76 76 TYR TYR A . n A 1 77 THR 77 77 77 THR THR A . n A 1 78 LEU 78 78 78 LEU LEU A . n A 1 79 MET 79 79 79 MET MET A . n A 1 80 THR 80 80 80 THR THR A . n A 1 81 GLY 81 81 81 GLY GLY A . n A 1 82 ARG 82 82 82 ARG ARG A . n A 1 83 HIS 83 83 83 HIS HIS A . n A 1 84 CYS 84 84 84 CYS CYS A . n A 1 85 GLU 85 85 85 GLU GLU A . n A 1 86 VAL 86 86 86 VAL VAL A . n A 1 87 HIS 87 87 87 HIS HIS A . n A 1 88 GLN 88 88 88 GLN GLN A . n A 1 89 MET 89 89 89 MET MET A . n A 1 90 ILE 90 90 90 ILE ILE A . n A 1 91 GLY 91 91 91 GLY GLY A . n A 1 92 ASN 92 92 92 ASN ASN A . n A 1 93 TYR 93 93 93 TYR TYR A . n A 1 94 MET 94 94 94 MET MET A . n A 1 95 TRP 95 95 95 TRP TRP A . n A 1 96 ASP 96 96 96 ASP ASP A . n A 1 97 PRO 97 97 97 PRO PRO A . n A 1 98 ARG 98 98 98 ARG ARG A . n A 1 99 THR 99 99 99 THR THR A . n A 1 100 ASN 100 100 100 ASN ASN A . n A 1 101 LYS 101 101 101 LYS LYS A . n A 1 102 SER 102 102 102 SER SER A . n A 1 103 PHE 103 103 103 PHE PHE A . n A 1 104 ASP 104 104 104 ASP ASP A . n A 1 105 ILE 105 105 105 ILE ILE A . n A 1 106 GLY 106 106 106 GLY GLY A . n A 1 107 VAL 107 107 107 VAL VAL A . n A 1 108 ASN 108 108 108 ASN ASN A . n A 1 109 ARG 109 109 109 ARG ARG A . n A 1 110 ASP 110 110 110 ASP ASP A . n A 1 111 SER 111 111 111 SER SER A . n A 1 112 LEU 112 112 112 LEU LEU A . n A 1 113 MET 113 113 113 MET MET A . n A 1 114 PRO 114 114 114 PRO PRO A . n A 1 115 LEU 115 115 115 LEU LEU A . n A 1 116 TRP 116 116 116 TRP TRP A . n A 1 117 TRP 117 117 117 TRP TRP A . n A 1 118 ASN 118 118 118 ASN ASN A . n A 1 119 GLY 119 119 119 GLY GLY A . n A 1 120 SER 120 120 120 SER SER A . n A 1 121 GLU 121 121 121 GLU GLU A . n A 1 122 PRO 122 122 122 PRO PRO A . n A 1 123 LEU 123 123 123 LEU LEU A . n A 1 124 TRP 124 124 124 TRP TRP A . n A 1 125 ILE 125 125 125 ILE ILE A . n A 1 126 THR 126 126 126 THR THR A . n A 1 127 LEU 127 127 127 LEU LEU A . n A 1 128 MET 128 128 128 MET MET A . n A 1 129 LYS 129 129 129 LYS LYS A . n A 1 130 ALA 130 130 130 ALA ALA A . n A 1 131 ARG 131 131 131 ARG ARG A . n A 1 132 ARG 132 132 132 ARG ARG A . n A 1 133 LYS 133 133 133 LYS LYS A . n A 1 134 VAL 134 134 134 VAL VAL A . n A 1 135 TYR 135 135 135 TYR TYR A . n A 1 136 MET 136 136 136 MET MET A . n A 1 137 TYR 137 137 137 TYR TYR A . n A 1 138 TYR 138 138 138 TYR TYR A . n A 1 139 TRP 139 139 139 TRP TRP A . n A 1 140 PRO 140 140 140 PRO PRO A . n A 1 141 GLY 141 141 141 GLY GLY A . n A 1 142 CYS 142 142 142 CYS CYS A . n A 1 143 GLU 143 143 143 GLU GLU A . n A 1 144 VAL 144 144 144 VAL VAL A . n A 1 145 GLU 145 145 145 GLU GLU A . n A 1 146 ILE 146 146 146 ILE ILE A . n A 1 147 LEU 147 147 147 LEU LEU A . n A 1 148 GLY 148 148 148 GLY GLY A . n A 1 149 VAL 149 149 149 VAL VAL A . n A 1 150 ARG 150 150 150 ARG ARG A . n A 1 151 PRO 151 151 151 PRO PRO A . n A 1 152 THR 152 152 152 THR THR A . n A 1 153 TYR 153 153 153 TYR TYR A . n A 1 154 CYS 154 154 154 CYS CYS A . n A 1 155 LEU 155 155 155 LEU LEU A . n A 1 156 GLU 156 156 156 GLU GLU A . n A 1 157 TYR 157 157 157 TYR TYR A . n A 1 158 LYS 158 158 158 LYS LYS A . n A 1 159 THR 159 159 159 THR THR A . n A 1 160 VAL 160 160 160 VAL VAL A . n A 1 161 PRO 161 161 161 PRO PRO A . n A 1 162 THR 162 162 162 THR THR A . n A 1 163 ASP 163 163 163 ASP ASP A . n A 1 164 ILE 164 164 164 ILE ILE A . n A 1 165 ASN 165 165 165 ASN ASN A . n A 1 166 PHE 166 166 166 PHE PHE A . n A 1 167 ALA 167 167 167 ALA ALA A . n A 1 168 ASN 168 168 168 ASN ASN A . n A 1 169 ALA 169 169 169 ALA ALA A . n A 1 170 VAL 170 170 170 VAL VAL A . n A 1 171 SER 171 171 171 SER SER A . n A 1 172 ASP 172 172 172 ASP ASP A . n A 1 173 ALA 173 173 173 ALA ALA A . n A 1 174 LEU 174 174 174 LEU LEU A . n A 1 175 ASP 175 175 175 ASP ASP A . n A 1 176 SER 176 176 176 SER SER A . n A 1 177 LEU 177 177 177 LEU LEU A . n A 1 178 LYS 178 178 178 LYS LYS A . n A 1 179 SER 179 179 179 SER SER A . n A 1 180 GLY 180 180 180 GLY GLY A . n A 1 181 ARG 181 181 181 ARG ARG A . n A 1 182 ALA 182 182 182 ALA ALA A . n A 1 183 ASP 183 183 183 ASP ASP A . n A 1 184 LEU 184 184 184 LEU LEU A . n A 1 185 ALA 185 185 185 ALA ALA A . n A 1 186 ALA 186 186 186 ALA ALA A . n A 1 187 ILE 187 187 187 ILE ILE A . n A 1 188 TYR 188 188 188 TYR TYR A . n A 1 189 HIS 189 189 189 HIS HIS A . n A 1 190 GLU 190 190 190 GLU GLU A . n A 1 191 ARG 191 191 191 ARG ARG A . n A 1 192 ILE 192 192 192 ILE ILE A . n A 1 193 ASP 193 193 193 ASP ASP A . n A 1 194 VAL 194 194 194 VAL VAL A . n A 1 195 GLU 195 195 195 GLU GLU A . n A 1 196 GLY 196 196 196 GLY GLY A . n A 1 197 HIS 197 197 197 HIS HIS A . n A 1 198 HIS 198 198 198 HIS HIS A . n A 1 199 TYR 199 199 199 TYR TYR A . n A 1 200 GLY 200 200 200 GLY GLY A . n A 1 201 PRO 201 201 201 PRO PRO A . n A 1 202 SER 202 202 202 SER SER A . n A 1 203 SER 203 203 203 SER SER A . n A 1 204 PRO 204 204 204 PRO PRO A . n A 1 205 GLN 205 205 205 GLN GLN A . n A 1 206 ARG 206 206 206 ARG ARG A . n A 1 207 LYS 207 207 207 LYS LYS A . n A 1 208 ASP 208 208 208 ASP ASP A . n A 1 209 ALA 209 209 209 ALA ALA A . n A 1 210 LEU 210 210 210 LEU LEU A . n A 1 211 ARG 211 211 211 ARG ARG A . n A 1 212 ALA 212 212 212 ALA ALA A . n A 1 213 VAL 213 213 213 VAL VAL A . n A 1 214 ASP 214 214 214 ASP ASP A . n A 1 215 THR 215 215 215 THR THR A . n A 1 216 VAL 216 216 216 VAL VAL A . n A 1 217 LEU 217 217 217 LEU LEU A . n A 1 218 LYS 218 218 218 LYS LYS A . n A 1 219 TYR 219 219 219 TYR TYR A . n A 1 220 MET 220 220 220 MET MET A . n A 1 221 ILE 221 221 221 ILE ILE A . n A 1 222 GLN 222 222 222 GLN GLN A . n A 1 223 TRP 223 223 223 TRP TRP A . n A 1 224 ILE 224 224 224 ILE ILE A . n A 1 225 GLN 225 225 225 GLN GLN A . n A 1 226 ASP 226 226 226 ASP ASP A . n A 1 227 ARG 227 227 227 ARG ARG A . n A 1 228 GLY 228 228 228 GLY GLY A . n A 1 229 LEU 229 229 229 LEU LEU A . n A 1 230 GLN 230 230 230 GLN GLN A . n A 1 231 GLN 231 231 231 GLN GLN A . n A 1 232 ASP 232 232 232 ASP ASP A . n A 1 233 LEU 233 233 233 LEU LEU A . n A 1 234 ASN 234 234 234 ASN ASN A . n A 1 235 VAL 235 235 235 VAL VAL A . n A 1 236 ILE 236 236 236 ILE ILE A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 PHE 238 238 238 PHE PHE A . n A 1 239 SER 239 239 239 SER SER A . n A 1 240 ASP 240 240 240 ASP ASP A . n A 1 241 HIS 241 241 241 HIS HIS A . n A 1 242 GLY 242 242 242 GLY GLY A . n A 1 243 MET 243 243 243 MET MET A . n A 1 244 THR 244 244 244 THR THR A . n A 1 245 ASP 245 245 245 ASP ASP A . n A 1 246 ILE 246 246 246 ILE ILE A . n A 1 247 PHE 247 247 247 PHE PHE A . n A 1 248 TRP 248 248 248 TRP TRP A . n A 1 249 MET 249 249 249 MET MET A . n A 1 250 ASP 250 250 250 ASP ASP A . n A 1 251 LYS 251 251 251 LYS LYS A . n A 1 252 VAL 252 252 252 VAL VAL A . n A 1 253 ILE 253 253 253 ILE ILE A . n A 1 254 GLU 254 254 254 GLU GLU A . n A 1 255 LEU 255 255 255 LEU LEU A . n A 1 256 SER 256 256 256 SER SER A . n A 1 257 ASN 257 257 257 ASN ASN A . n A 1 258 TYR 258 258 258 TYR TYR A . n A 1 259 ILE 259 259 259 ILE ILE A . n A 1 260 SER 260 260 260 SER SER A . n A 1 261 LEU 261 261 261 LEU LEU A . n A 1 262 ASP 262 262 262 ASP ASP A . n A 1 263 ASP 263 263 263 ASP ASP A . n A 1 264 LEU 264 264 264 LEU LEU A . n A 1 265 GLN 265 265 265 GLN GLN A . n A 1 266 GLN 266 266 266 GLN GLN A . n A 1 267 VAL 267 267 267 VAL VAL A . n A 1 268 LYS 268 268 268 LYS LYS A . n A 1 269 ASP 269 269 269 ASP ASP A . n A 1 270 ARG 270 270 270 ARG ARG A . n A 1 271 GLY 271 271 271 GLY GLY A . n A 1 272 PRO 272 272 272 PRO PRO A . n A 1 273 VAL 273 273 273 VAL VAL A . n A 1 274 VAL 274 274 274 VAL VAL A . n A 1 275 SER 275 275 275 SER SER A . n A 1 276 LEU 276 276 276 LEU LEU A . n A 1 277 TRP 277 277 277 TRP TRP A . n A 1 278 PRO 278 278 278 PRO PRO A . n A 1 279 VAL 279 279 279 VAL VAL A . n A 1 280 PRO 280 280 280 PRO PRO A . n A 1 281 GLY 281 281 281 GLY GLY A . n A 1 282 LYS 282 282 282 LYS LYS A . n A 1 283 HIS 283 283 283 HIS HIS A . n A 1 284 SER 284 284 284 SER SER A . n A 1 285 GLU 285 285 285 GLU GLU A . n A 1 286 ILE 286 286 286 ILE ILE A . n A 1 287 TYR 287 287 287 TYR TYR A . n A 1 288 HIS 288 288 288 HIS HIS A . n A 1 289 LYS 289 289 289 LYS LYS A . n A 1 290 LEU 290 290 290 LEU LEU A . n A 1 291 ARG 291 291 291 ARG ARG A . n A 1 292 THR 292 292 292 THR THR A . n A 1 293 VAL 293 293 293 VAL VAL A . n A 1 294 GLU 294 294 294 GLU GLU A . n A 1 295 HIS 295 295 295 HIS HIS A . n A 1 296 MET 296 296 296 MET MET A . n A 1 297 THR 297 297 297 THR THR A . n A 1 298 VAL 298 298 298 VAL VAL A . n A 1 299 TYR 299 299 299 TYR TYR A . n A 1 300 GLU 300 300 300 GLU GLU A . n A 1 301 LYS 301 301 301 LYS LYS A . n A 1 302 GLU 302 302 302 GLU GLU A . n A 1 303 SER 303 303 303 SER SER A . n A 1 304 ILE 304 304 304 ILE ILE A . n A 1 305 PRO 305 305 305 PRO PRO A . n A 1 306 ASN 306 306 306 ASN ASN A . n A 1 307 ARG 307 307 307 ARG ARG A . n A 1 308 PHE 308 308 308 PHE PHE A . n A 1 309 TYR 309 309 309 TYR TYR A . n A 1 310 TYR 310 310 310 TYR TYR A . n A 1 311 LYS 311 311 311 LYS LYS A . n A 1 312 LYS 312 312 312 LYS LYS A . n A 1 313 GLY 313 313 313 GLY GLY A . n A 1 314 LYS 314 314 314 LYS LYS A . n A 1 315 PHE 315 315 315 PHE PHE A . n A 1 316 VAL 316 316 316 VAL VAL A . n A 1 317 SER 317 317 317 SER SER A . n A 1 318 PRO 318 318 318 PRO PRO A . n A 1 319 LEU 319 319 319 LEU LEU A . n A 1 320 THR 320 320 320 THR THR A . n A 1 321 LEU 321 321 321 LEU LEU A . n A 1 322 VAL 322 322 322 VAL VAL A . n A 1 323 ALA 323 323 323 ALA ALA A . n A 1 324 ASP 324 324 324 ASP ASP A . n A 1 325 GLU 325 325 325 GLU GLU A . n A 1 326 GLY 326 326 326 GLY GLY A . n A 1 327 TRP 327 327 327 TRP TRP A . n A 1 328 PHE 328 328 328 PHE PHE A . n A 1 329 ILE 329 329 329 ILE ILE A . n A 1 330 ALA 330 330 330 ALA ALA A . n A 1 331 GLU 331 331 331 GLU GLU A . n A 1 332 SER 332 332 332 SER SER A . n A 1 333 ARG 333 333 333 ARG ARG A . n A 1 334 GLU 334 334 334 GLU GLU A . n A 1 335 MET 335 335 335 MET MET A . n A 1 336 LEU 336 336 336 LEU LEU A . n A 1 337 PRO 337 337 337 PRO PRO A . n A 1 338 PHE 338 338 338 PHE PHE A . n A 1 339 TRP 339 339 339 TRP TRP A . n A 1 340 MET 340 340 340 MET MET A . n A 1 341 ASN 341 341 341 ASN ASN A . n A 1 342 SER 342 342 342 SER SER A . n A 1 343 THR 343 343 343 THR THR A . n A 1 344 GLY 344 344 344 GLY GLY A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 ARG 346 346 346 ARG ARG A . n A 1 347 GLU 347 347 347 GLU GLU A . n A 1 348 GLY 348 348 348 GLY GLY A . n A 1 349 TRP 349 349 349 TRP TRP A . n A 1 350 GLN 350 350 350 GLN GLN A . n A 1 351 ARG 351 351 351 ARG ARG A . n A 1 352 GLY 352 352 352 GLY GLY A . n A 1 353 TRP 353 353 353 TRP TRP A . n A 1 354 HIS 354 354 354 HIS HIS A . n A 1 355 GLY 355 355 355 GLY GLY A . n A 1 356 TYR 356 356 356 TYR TYR A . n A 1 357 ASP 357 357 357 ASP ASP A . n A 1 358 ASN 358 358 358 ASN ASN A . n A 1 359 GLU 359 359 359 GLU GLU A . n A 1 360 LEU 360 360 360 LEU LEU A . n A 1 361 MET 361 361 361 MET MET A . n A 1 362 ASP 362 362 362 ASP ASP A . n A 1 363 MET 363 363 363 MET MET A . n A 1 364 ARG 364 364 364 ARG ARG A . n A 1 365 GLY 365 365 365 GLY GLY A . n A 1 366 ILE 366 366 366 ILE ILE A . n A 1 367 PHE 367 367 367 PHE PHE A . n A 1 368 LEU 368 368 368 LEU LEU A . n A 1 369 ALA 369 369 369 ALA ALA A . n A 1 370 ILE 370 370 370 ILE ILE A . n A 1 371 GLY 371 371 371 GLY GLY A . n A 1 372 PRO 372 372 372 PRO PRO A . n A 1 373 ASP 373 373 373 ASP ASP A . n A 1 374 PHE 374 374 374 PHE PHE A . n A 1 375 LYS 375 375 375 LYS LYS A . n A 1 376 SER 376 376 376 SER SER A . n A 1 377 ASN 377 377 377 ASN ASN A . n A 1 378 PHE 378 378 378 PHE PHE A . n A 1 379 ARG 379 379 379 ARG ARG A . n A 1 380 ALA 380 380 380 ALA ALA A . n A 1 381 ALA 381 381 381 ALA ALA A . n A 1 382 PRO 382 382 382 PRO PRO A . n A 1 383 ILE 383 383 383 ILE ILE A . n A 1 384 ARG 384 384 384 ARG ARG A . n A 1 385 SER 385 385 385 SER SER A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 ASP 387 387 387 ASP ASP A . n A 1 388 VAL 388 388 388 VAL VAL A . n A 1 389 TYR 389 389 389 TYR TYR A . n A 1 390 ASN 390 390 390 ASN ASN A . n A 1 391 ILE 391 391 391 ILE ILE A . n A 1 392 MET 392 392 392 MET MET A . n A 1 393 ALA 393 393 393 ALA ALA A . n A 1 394 HIS 394 394 394 HIS HIS A . n A 1 395 VAL 395 395 395 VAL VAL A . n A 1 396 ALA 396 396 396 ALA ALA A . n A 1 397 GLY 397 397 397 GLY GLY A . n A 1 398 ILE 398 398 398 ILE ILE A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 PRO 400 400 400 PRO PRO A . n A 1 401 LEU 401 401 401 LEU LEU A . n A 1 402 PRO 402 402 402 PRO PRO A . n A 1 403 ASN 403 403 403 ASN ASN A . n A 1 404 ASN 404 404 404 ASN ASN A . n A 1 405 GLY 405 405 405 GLY GLY A . n A 1 406 SER 406 406 406 SER SER A . n A 1 407 TRP 407 407 407 TRP TRP A . n A 1 408 SER 408 408 408 SER SER A . n A 1 409 ARG 409 409 409 ARG ARG A . n A 1 410 VAL 410 410 410 VAL VAL A . n A 1 411 VAL 411 411 411 VAL VAL A . n A 1 412 SER 412 412 412 SER SER A . n A 1 413 MET 413 413 413 MET MET A . n A 1 414 LEU 414 414 414 LEU LEU A . n A 1 415 LYS 415 415 415 LYS LYS A . n A 1 416 GLY 416 416 ? ? ? A . n A 1 417 GLN 417 417 ? ? ? A . n A 1 418 THR 418 418 ? ? ? A . n A 1 419 SER 419 419 ? ? ? A . n A 1 420 SER 420 420 ? ? ? A . n A 1 421 ALA 421 421 ? ? ? A . n A 1 422 SER 422 422 ? ? ? A . n A 1 423 ARG 423 423 ? ? ? A . n A 1 424 GLU 424 424 ? ? ? A . n A 1 425 ASN 425 425 ? ? ? A . n A 1 426 LEU 426 426 ? ? ? A . n A 1 427 TYR 427 427 ? ? ? A . n A 1 428 PHE 428 428 ? ? ? A . n A 1 429 GLN 429 429 ? ? ? A . n B 1 1 MET 1 1 ? ? ? B . n B 1 2 ALA 2 2 ? ? ? B . n B 1 3 ALA 3 3 ? ? ? B . n B 1 4 LYS 4 4 ? ? ? B . n B 1 5 LEU 5 5 ? ? ? B . n B 1 6 TRP 6 6 ? ? ? B . n B 1 7 THR 7 7 ? ? ? B . n B 1 8 PHE 8 8 ? ? ? B . n B 1 9 LEU 9 9 ? ? ? B . n B 1 10 LEU 10 10 ? ? ? B . n B 1 11 GLY 11 11 ? ? ? B . n B 1 12 PHE 12 12 ? ? ? B . n B 1 13 GLY 13 13 ? ? ? B . n B 1 14 LEU 14 14 ? ? ? B . n B 1 15 SER 15 15 ? ? ? B . n B 1 16 TRP 16 16 ? ? ? B . n B 1 17 VAL 17 17 ? ? ? B . n B 1 18 TRP 18 18 ? ? ? B . n B 1 19 PRO 19 19 ? ? ? B . n B 1 20 ALA 20 20 ? ? ? B . n B 1 21 SER 21 21 ? ? ? B . n B 1 22 ALA 22 22 ? ? ? B . n B 1 23 HIS 23 23 23 HIS HIS B . n B 1 24 ARG 24 24 24 ARG ARG B . n B 1 25 LYS 25 25 25 LYS LYS B . n B 1 26 LEU 26 26 26 LEU LEU B . n B 1 27 LEU 27 27 27 LEU LEU B . n B 1 28 VAL 28 28 28 VAL VAL B . n B 1 29 LEU 29 29 29 LEU LEU B . n B 1 30 LEU 30 30 30 LEU LEU B . n B 1 31 LEU 31 31 31 LEU LEU B . n B 1 32 ASP 32 32 32 ASP ASP B . n B 1 33 GLY 33 33 33 GLY GLY B . n B 1 34 PHE 34 34 34 PHE PHE B . n B 1 35 ARG 35 35 35 ARG ARG B . n B 1 36 SER 36 36 36 SER SER B . n B 1 37 ASP 37 37 37 ASP ASP B . n B 1 38 TYR 38 38 38 TYR TYR B . n B 1 39 ILE 39 39 39 ILE ILE B . n B 1 40 SER 40 40 40 SER SER B . n B 1 41 GLU 41 41 41 GLU GLU B . n B 1 42 ASP 42 42 42 ASP ASP B . n B 1 43 ALA 43 43 43 ALA ALA B . n B 1 44 LEU 44 44 44 LEU LEU B . n B 1 45 ALA 45 45 45 ALA ALA B . n B 1 46 SER 46 46 46 SER SER B . n B 1 47 LEU 47 47 47 LEU LEU B . n B 1 48 PRO 48 48 48 PRO PRO B . n B 1 49 GLY 49 49 49 GLY GLY B . n B 1 50 PHE 50 50 50 PHE PHE B . n B 1 51 ARG 51 51 51 ARG ARG B . n B 1 52 GLU 52 52 52 GLU GLU B . n B 1 53 ILE 53 53 53 ILE ILE B . n B 1 54 VAL 54 54 54 VAL VAL B . n B 1 55 ASN 55 55 55 ASN ASN B . n B 1 56 ARG 56 56 56 ARG ARG B . n B 1 57 GLY 57 57 57 GLY GLY B . n B 1 58 VAL 58 58 58 VAL VAL B . n B 1 59 LYS 59 59 59 LYS LYS B . n B 1 60 VAL 60 60 60 VAL VAL B . n B 1 61 ASP 61 61 61 ASP ASP B . n B 1 62 TYR 62 62 62 TYR TYR B . n B 1 63 LEU 63 63 63 LEU LEU B . n B 1 64 THR 64 64 64 THR THR B . n B 1 65 PRO 65 65 65 PRO PRO B . n B 1 66 ASP 66 66 66 ASP ASP B . n B 1 67 PHE 67 67 67 PHE PHE B . n B 1 68 PRO 68 68 68 PRO PRO B . n B 1 69 SER 69 69 69 SER SER B . n B 1 70 LEU 70 70 70 LEU LEU B . n B 1 71 SER 71 71 71 SER SER B . n B 1 72 TYR 72 72 72 TYR TYR B . n B 1 73 PRO 73 73 73 PRO PRO B . n B 1 74 ASN 74 74 74 ASN ASN B . n B 1 75 TYR 75 75 75 TYR TYR B . n B 1 76 TYR 76 76 76 TYR TYR B . n B 1 77 THR 77 77 77 THR THR B . n B 1 78 LEU 78 78 78 LEU LEU B . n B 1 79 MET 79 79 79 MET MET B . n B 1 80 THR 80 80 80 THR THR B . n B 1 81 GLY 81 81 81 GLY GLY B . n B 1 82 ARG 82 82 82 ARG ARG B . n B 1 83 HIS 83 83 83 HIS HIS B . n B 1 84 CYS 84 84 84 CYS CYS B . n B 1 85 GLU 85 85 85 GLU GLU B . n B 1 86 VAL 86 86 86 VAL VAL B . n B 1 87 HIS 87 87 87 HIS HIS B . n B 1 88 GLN 88 88 88 GLN GLN B . n B 1 89 MET 89 89 89 MET MET B . n B 1 90 ILE 90 90 90 ILE ILE B . n B 1 91 GLY 91 91 91 GLY GLY B . n B 1 92 ASN 92 92 92 ASN ASN B . n B 1 93 TYR 93 93 93 TYR TYR B . n B 1 94 MET 94 94 94 MET MET B . n B 1 95 TRP 95 95 95 TRP TRP B . n B 1 96 ASP 96 96 96 ASP ASP B . n B 1 97 PRO 97 97 97 PRO PRO B . n B 1 98 ARG 98 98 98 ARG ARG B . n B 1 99 THR 99 99 99 THR THR B . n B 1 100 ASN 100 100 100 ASN ASN B . n B 1 101 LYS 101 101 101 LYS LYS B . n B 1 102 SER 102 102 102 SER SER B . n B 1 103 PHE 103 103 103 PHE PHE B . n B 1 104 ASP 104 104 104 ASP ASP B . n B 1 105 ILE 105 105 105 ILE ILE B . n B 1 106 GLY 106 106 106 GLY GLY B . n B 1 107 VAL 107 107 107 VAL VAL B . n B 1 108 ASN 108 108 108 ASN ASN B . n B 1 109 ARG 109 109 109 ARG ARG B . n B 1 110 ASP 110 110 110 ASP ASP B . n B 1 111 SER 111 111 111 SER SER B . n B 1 112 LEU 112 112 112 LEU LEU B . n B 1 113 MET 113 113 113 MET MET B . n B 1 114 PRO 114 114 114 PRO PRO B . n B 1 115 LEU 115 115 115 LEU LEU B . n B 1 116 TRP 116 116 116 TRP TRP B . n B 1 117 TRP 117 117 117 TRP TRP B . n B 1 118 ASN 118 118 118 ASN ASN B . n B 1 119 GLY 119 119 119 GLY GLY B . n B 1 120 SER 120 120 120 SER SER B . n B 1 121 GLU 121 121 121 GLU GLU B . n B 1 122 PRO 122 122 122 PRO PRO B . n B 1 123 LEU 123 123 123 LEU LEU B . n B 1 124 TRP 124 124 124 TRP TRP B . n B 1 125 ILE 125 125 125 ILE ILE B . n B 1 126 THR 126 126 126 THR THR B . n B 1 127 LEU 127 127 127 LEU LEU B . n B 1 128 MET 128 128 128 MET MET B . n B 1 129 LYS 129 129 129 LYS LYS B . n B 1 130 ALA 130 130 130 ALA ALA B . n B 1 131 ARG 131 131 131 ARG ARG B . n B 1 132 ARG 132 132 132 ARG ARG B . n B 1 133 LYS 133 133 133 LYS LYS B . n B 1 134 VAL 134 134 134 VAL VAL B . n B 1 135 TYR 135 135 135 TYR TYR B . n B 1 136 MET 136 136 136 MET MET B . n B 1 137 TYR 137 137 137 TYR TYR B . n B 1 138 TYR 138 138 138 TYR TYR B . n B 1 139 TRP 139 139 139 TRP TRP B . n B 1 140 PRO 140 140 140 PRO PRO B . n B 1 141 GLY 141 141 141 GLY GLY B . n B 1 142 CYS 142 142 142 CYS CYS B . n B 1 143 GLU 143 143 143 GLU GLU B . n B 1 144 VAL 144 144 144 VAL VAL B . n B 1 145 GLU 145 145 145 GLU GLU B . n B 1 146 ILE 146 146 146 ILE ILE B . n B 1 147 LEU 147 147 147 LEU LEU B . n B 1 148 GLY 148 148 148 GLY GLY B . n B 1 149 VAL 149 149 149 VAL VAL B . n B 1 150 ARG 150 150 150 ARG ARG B . n B 1 151 PRO 151 151 151 PRO PRO B . n B 1 152 THR 152 152 152 THR THR B . n B 1 153 TYR 153 153 153 TYR TYR B . n B 1 154 CYS 154 154 154 CYS CYS B . n B 1 155 LEU 155 155 155 LEU LEU B . n B 1 156 GLU 156 156 156 GLU GLU B . n B 1 157 TYR 157 157 157 TYR TYR B . n B 1 158 LYS 158 158 158 LYS LYS B . n B 1 159 THR 159 159 159 THR THR B . n B 1 160 VAL 160 160 160 VAL VAL B . n B 1 161 PRO 161 161 161 PRO PRO B . n B 1 162 THR 162 162 162 THR THR B . n B 1 163 ASP 163 163 163 ASP ASP B . n B 1 164 ILE 164 164 164 ILE ILE B . n B 1 165 ASN 165 165 165 ASN ASN B . n B 1 166 PHE 166 166 166 PHE PHE B . n B 1 167 ALA 167 167 167 ALA ALA B . n B 1 168 ASN 168 168 168 ASN ASN B . n B 1 169 ALA 169 169 169 ALA ALA B . n B 1 170 VAL 170 170 170 VAL VAL B . n B 1 171 SER 171 171 171 SER SER B . n B 1 172 ASP 172 172 172 ASP ASP B . n B 1 173 ALA 173 173 173 ALA ALA B . n B 1 174 LEU 174 174 174 LEU LEU B . n B 1 175 ASP 175 175 175 ASP ASP B . n B 1 176 SER 176 176 176 SER SER B . n B 1 177 LEU 177 177 177 LEU LEU B . n B 1 178 LYS 178 178 178 LYS LYS B . n B 1 179 SER 179 179 179 SER SER B . n B 1 180 GLY 180 180 180 GLY GLY B . n B 1 181 ARG 181 181 181 ARG ARG B . n B 1 182 ALA 182 182 182 ALA ALA B . n B 1 183 ASP 183 183 183 ASP ASP B . n B 1 184 LEU 184 184 184 LEU LEU B . n B 1 185 ALA 185 185 185 ALA ALA B . n B 1 186 ALA 186 186 186 ALA ALA B . n B 1 187 ILE 187 187 187 ILE ILE B . n B 1 188 TYR 188 188 188 TYR TYR B . n B 1 189 HIS 189 189 189 HIS HIS B . n B 1 190 GLU 190 190 190 GLU GLU B . n B 1 191 ARG 191 191 191 ARG ARG B . n B 1 192 ILE 192 192 192 ILE ILE B . n B 1 193 ASP 193 193 193 ASP ASP B . n B 1 194 VAL 194 194 194 VAL VAL B . n B 1 195 GLU 195 195 195 GLU GLU B . n B 1 196 GLY 196 196 196 GLY GLY B . n B 1 197 HIS 197 197 197 HIS HIS B . n B 1 198 HIS 198 198 198 HIS HIS B . n B 1 199 TYR 199 199 199 TYR TYR B . n B 1 200 GLY 200 200 200 GLY GLY B . n B 1 201 PRO 201 201 201 PRO PRO B . n B 1 202 SER 202 202 202 SER SER B . n B 1 203 SER 203 203 203 SER SER B . n B 1 204 PRO 204 204 204 PRO PRO B . n B 1 205 GLN 205 205 205 GLN GLN B . n B 1 206 ARG 206 206 206 ARG ARG B . n B 1 207 LYS 207 207 207 LYS LYS B . n B 1 208 ASP 208 208 208 ASP ASP B . n B 1 209 ALA 209 209 209 ALA ALA B . n B 1 210 LEU 210 210 210 LEU LEU B . n B 1 211 ARG 211 211 211 ARG ARG B . n B 1 212 ALA 212 212 212 ALA ALA B . n B 1 213 VAL 213 213 213 VAL VAL B . n B 1 214 ASP 214 214 214 ASP ASP B . n B 1 215 THR 215 215 215 THR THR B . n B 1 216 VAL 216 216 216 VAL VAL B . n B 1 217 LEU 217 217 217 LEU LEU B . n B 1 218 LYS 218 218 218 LYS LYS B . n B 1 219 TYR 219 219 219 TYR TYR B . n B 1 220 MET 220 220 220 MET MET B . n B 1 221 ILE 221 221 221 ILE ILE B . n B 1 222 GLN 222 222 222 GLN GLN B . n B 1 223 TRP 223 223 223 TRP TRP B . n B 1 224 ILE 224 224 224 ILE ILE B . n B 1 225 GLN 225 225 225 GLN GLN B . n B 1 226 ASP 226 226 226 ASP ASP B . n B 1 227 ARG 227 227 227 ARG ARG B . n B 1 228 GLY 228 228 228 GLY GLY B . n B 1 229 LEU 229 229 229 LEU LEU B . n B 1 230 GLN 230 230 230 GLN GLN B . n B 1 231 GLN 231 231 231 GLN GLN B . n B 1 232 ASP 232 232 232 ASP ASP B . n B 1 233 LEU 233 233 233 LEU LEU B . n B 1 234 ASN 234 234 234 ASN ASN B . n B 1 235 VAL 235 235 235 VAL VAL B . n B 1 236 ILE 236 236 236 ILE ILE B . n B 1 237 LEU 237 237 237 LEU LEU B . n B 1 238 PHE 238 238 238 PHE PHE B . n B 1 239 SER 239 239 239 SER SER B . n B 1 240 ASP 240 240 240 ASP ASP B . n B 1 241 HIS 241 241 241 HIS HIS B . n B 1 242 GLY 242 242 242 GLY GLY B . n B 1 243 MET 243 243 243 MET MET B . n B 1 244 THR 244 244 244 THR THR B . n B 1 245 ASP 245 245 245 ASP ASP B . n B 1 246 ILE 246 246 246 ILE ILE B . n B 1 247 PHE 247 247 247 PHE PHE B . n B 1 248 TRP 248 248 248 TRP TRP B . n B 1 249 MET 249 249 249 MET MET B . n B 1 250 ASP 250 250 250 ASP ASP B . n B 1 251 LYS 251 251 251 LYS LYS B . n B 1 252 VAL 252 252 252 VAL VAL B . n B 1 253 ILE 253 253 253 ILE ILE B . n B 1 254 GLU 254 254 254 GLU GLU B . n B 1 255 LEU 255 255 255 LEU LEU B . n B 1 256 SER 256 256 256 SER SER B . n B 1 257 ASN 257 257 257 ASN ASN B . n B 1 258 TYR 258 258 258 TYR TYR B . n B 1 259 ILE 259 259 259 ILE ILE B . n B 1 260 SER 260 260 260 SER SER B . n B 1 261 LEU 261 261 261 LEU LEU B . n B 1 262 ASP 262 262 262 ASP ASP B . n B 1 263 ASP 263 263 263 ASP ASP B . n B 1 264 LEU 264 264 264 LEU LEU B . n B 1 265 GLN 265 265 265 GLN GLN B . n B 1 266 GLN 266 266 266 GLN GLN B . n B 1 267 VAL 267 267 267 VAL VAL B . n B 1 268 LYS 268 268 268 LYS LYS B . n B 1 269 ASP 269 269 269 ASP ASP B . n B 1 270 ARG 270 270 270 ARG ARG B . n B 1 271 GLY 271 271 271 GLY GLY B . n B 1 272 PRO 272 272 272 PRO PRO B . n B 1 273 VAL 273 273 273 VAL VAL B . n B 1 274 VAL 274 274 274 VAL VAL B . n B 1 275 SER 275 275 275 SER SER B . n B 1 276 LEU 276 276 276 LEU LEU B . n B 1 277 TRP 277 277 277 TRP TRP B . n B 1 278 PRO 278 278 278 PRO PRO B . n B 1 279 VAL 279 279 279 VAL VAL B . n B 1 280 PRO 280 280 280 PRO PRO B . n B 1 281 GLY 281 281 281 GLY GLY B . n B 1 282 LYS 282 282 282 LYS LYS B . n B 1 283 HIS 283 283 283 HIS HIS B . n B 1 284 SER 284 284 284 SER SER B . n B 1 285 GLU 285 285 285 GLU GLU B . n B 1 286 ILE 286 286 286 ILE ILE B . n B 1 287 TYR 287 287 287 TYR TYR B . n B 1 288 HIS 288 288 288 HIS HIS B . n B 1 289 LYS 289 289 289 LYS LYS B . n B 1 290 LEU 290 290 290 LEU LEU B . n B 1 291 ARG 291 291 291 ARG ARG B . n B 1 292 THR 292 292 292 THR THR B . n B 1 293 VAL 293 293 293 VAL VAL B . n B 1 294 GLU 294 294 294 GLU GLU B . n B 1 295 HIS 295 295 295 HIS HIS B . n B 1 296 MET 296 296 296 MET MET B . n B 1 297 THR 297 297 297 THR THR B . n B 1 298 VAL 298 298 298 VAL VAL B . n B 1 299 TYR 299 299 299 TYR TYR B . n B 1 300 GLU 300 300 300 GLU GLU B . n B 1 301 LYS 301 301 301 LYS LYS B . n B 1 302 GLU 302 302 302 GLU GLU B . n B 1 303 SER 303 303 303 SER SER B . n B 1 304 ILE 304 304 304 ILE ILE B . n B 1 305 PRO 305 305 305 PRO PRO B . n B 1 306 ASN 306 306 306 ASN ASN B . n B 1 307 ARG 307 307 307 ARG ARG B . n B 1 308 PHE 308 308 308 PHE PHE B . n B 1 309 TYR 309 309 309 TYR TYR B . n B 1 310 TYR 310 310 310 TYR TYR B . n B 1 311 LYS 311 311 311 LYS LYS B . n B 1 312 LYS 312 312 312 LYS LYS B . n B 1 313 GLY 313 313 313 GLY GLY B . n B 1 314 LYS 314 314 314 LYS LYS B . n B 1 315 PHE 315 315 315 PHE PHE B . n B 1 316 VAL 316 316 316 VAL VAL B . n B 1 317 SER 317 317 317 SER SER B . n B 1 318 PRO 318 318 318 PRO PRO B . n B 1 319 LEU 319 319 319 LEU LEU B . n B 1 320 THR 320 320 320 THR THR B . n B 1 321 LEU 321 321 321 LEU LEU B . n B 1 322 VAL 322 322 322 VAL VAL B . n B 1 323 ALA 323 323 323 ALA ALA B . n B 1 324 ASP 324 324 324 ASP ASP B . n B 1 325 GLU 325 325 325 GLU GLU B . n B 1 326 GLY 326 326 326 GLY GLY B . n B 1 327 TRP 327 327 327 TRP TRP B . n B 1 328 PHE 328 328 328 PHE PHE B . n B 1 329 ILE 329 329 329 ILE ILE B . n B 1 330 ALA 330 330 330 ALA ALA B . n B 1 331 GLU 331 331 331 GLU GLU B . n B 1 332 SER 332 332 332 SER SER B . n B 1 333 ARG 333 333 333 ARG ARG B . n B 1 334 GLU 334 334 334 GLU GLU B . n B 1 335 MET 335 335 335 MET MET B . n B 1 336 LEU 336 336 336 LEU LEU B . n B 1 337 PRO 337 337 337 PRO PRO B . n B 1 338 PHE 338 338 338 PHE PHE B . n B 1 339 TRP 339 339 339 TRP TRP B . n B 1 340 MET 340 340 340 MET MET B . n B 1 341 ASN 341 341 341 ASN ASN B . n B 1 342 SER 342 342 342 SER SER B . n B 1 343 THR 343 343 343 THR THR B . n B 1 344 GLY 344 344 344 GLY GLY B . n B 1 345 LYS 345 345 345 LYS LYS B . n B 1 346 ARG 346 346 346 ARG ARG B . n B 1 347 GLU 347 347 347 GLU GLU B . n B 1 348 GLY 348 348 348 GLY GLY B . n B 1 349 TRP 349 349 349 TRP TRP B . n B 1 350 GLN 350 350 350 GLN GLN B . n B 1 351 ARG 351 351 351 ARG ARG B . n B 1 352 GLY 352 352 352 GLY GLY B . n B 1 353 TRP 353 353 353 TRP TRP B . n B 1 354 HIS 354 354 354 HIS HIS B . n B 1 355 GLY 355 355 355 GLY GLY B . n B 1 356 TYR 356 356 356 TYR TYR B . n B 1 357 ASP 357 357 357 ASP ASP B . n B 1 358 ASN 358 358 358 ASN ASN B . n B 1 359 GLU 359 359 359 GLU GLU B . n B 1 360 LEU 360 360 360 LEU LEU B . n B 1 361 MET 361 361 361 MET MET B . n B 1 362 ASP 362 362 362 ASP ASP B . n B 1 363 MET 363 363 363 MET MET B . n B 1 364 ARG 364 364 364 ARG ARG B . n B 1 365 GLY 365 365 365 GLY GLY B . n B 1 366 ILE 366 366 366 ILE ILE B . n B 1 367 PHE 367 367 367 PHE PHE B . n B 1 368 LEU 368 368 368 LEU LEU B . n B 1 369 ALA 369 369 369 ALA ALA B . n B 1 370 ILE 370 370 370 ILE ILE B . n B 1 371 GLY 371 371 371 GLY GLY B . n B 1 372 PRO 372 372 372 PRO PRO B . n B 1 373 ASP 373 373 373 ASP ASP B . n B 1 374 PHE 374 374 374 PHE PHE B . n B 1 375 LYS 375 375 375 LYS LYS B . n B 1 376 SER 376 376 376 SER SER B . n B 1 377 ASN 377 377 377 ASN ASN B . n B 1 378 PHE 378 378 378 PHE PHE B . n B 1 379 ARG 379 379 379 ARG ARG B . n B 1 380 ALA 380 380 380 ALA ALA B . n B 1 381 ALA 381 381 381 ALA ALA B . n B 1 382 PRO 382 382 382 PRO PRO B . n B 1 383 ILE 383 383 383 ILE ILE B . n B 1 384 ARG 384 384 384 ARG ARG B . n B 1 385 SER 385 385 385 SER SER B . n B 1 386 VAL 386 386 386 VAL VAL B . n B 1 387 ASP 387 387 387 ASP ASP B . n B 1 388 VAL 388 388 388 VAL VAL B . n B 1 389 TYR 389 389 389 TYR TYR B . n B 1 390 ASN 390 390 390 ASN ASN B . n B 1 391 ILE 391 391 391 ILE ILE B . n B 1 392 MET 392 392 392 MET MET B . n B 1 393 ALA 393 393 393 ALA ALA B . n B 1 394 HIS 394 394 394 HIS HIS B . n B 1 395 VAL 395 395 395 VAL VAL B . n B 1 396 ALA 396 396 396 ALA ALA B . n B 1 397 GLY 397 397 397 GLY GLY B . n B 1 398 ILE 398 398 398 ILE ILE B . n B 1 399 THR 399 399 399 THR THR B . n B 1 400 PRO 400 400 400 PRO PRO B . n B 1 401 LEU 401 401 401 LEU LEU B . n B 1 402 PRO 402 402 402 PRO PRO B . n B 1 403 ASN 403 403 403 ASN ASN B . n B 1 404 ASN 404 404 404 ASN ASN B . n B 1 405 GLY 405 405 405 GLY GLY B . n B 1 406 SER 406 406 406 SER SER B . n B 1 407 TRP 407 407 407 TRP TRP B . n B 1 408 SER 408 408 408 SER SER B . n B 1 409 ARG 409 409 409 ARG ARG B . n B 1 410 VAL 410 410 410 VAL VAL B . n B 1 411 VAL 411 411 411 VAL VAL B . n B 1 412 SER 412 412 412 SER SER B . n B 1 413 MET 413 413 413 MET MET B . n B 1 414 LEU 414 414 414 LEU LEU B . n B 1 415 LYS 415 415 415 LYS LYS B . n B 1 416 GLY 416 416 ? ? ? B . n B 1 417 GLN 417 417 ? ? ? B . n B 1 418 THR 418 418 ? ? ? B . n B 1 419 SER 419 419 ? ? ? B . n B 1 420 SER 420 420 ? ? ? B . n B 1 421 ALA 421 421 ? ? ? B . n B 1 422 SER 422 422 ? ? ? B . n B 1 423 ARG 423 423 ? ? ? B . n B 1 424 GLU 424 424 ? ? ? B . n B 1 425 ASN 425 425 ? ? ? B . n B 1 426 LEU 426 426 ? ? ? B . n B 1 427 TYR 427 427 ? ? ? B . n B 1 428 PHE 428 428 ? ? ? B . n B 1 429 GLN 429 429 ? ? ? B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 501 502 NAG NAG A . D 2 NAG 2 502 508 NAG NAG A . E 2 NAG 1 503 503 NAG NAG A . F 2 NAG 2 504 504 NAG NAG A . G 3 FUL 3 505 505 FUL FUC A . H 2 NAG 1 506 506 NAG NAG A . I 2 NAG 2 507 507 NAG NAG A . J 4 ZN 1 508 1 ZN ZN A . K 4 ZN 1 509 1 ZN ZN A . L 5 EDO 1 510 1 EDO EDO A . M 5 EDO 1 511 2 EDO EDO A . N 6 PC 1 512 1 PC PC A . O 5 EDO 1 513 1 EDO EDO A . P 2 NAG 1 501 502 NAG NAG B . Q 2 NAG 1 502 503 NAG NAG B . R 3 FUL 2 503 505 FUL FUC B . S 2 NAG 3 504 508 NAG NAG B . T 2 NAG 1 505 506 NAG NAG B . U 2 NAG 2 506 507 NAG NAG B . V 4 ZN 1 507 1 ZN ZN B . W 4 ZN 1 508 1 ZN ZN B . X 5 EDO 1 509 1 EDO EDO B . Y 6 PC 1 510 2 PC PC B . Z 5 EDO 1 511 1 EDO EDO B . AA 7 HOH 1 601 428 HOH HOH A . AA 7 HOH 2 602 379 HOH HOH A . AA 7 HOH 3 603 110 HOH HOH A . AA 7 HOH 4 604 385 HOH HOH A . AA 7 HOH 5 605 417 HOH HOH A . AA 7 HOH 6 606 447 HOH HOH A . AA 7 HOH 7 607 31 HOH HOH A . AA 7 HOH 8 608 381 HOH HOH A . AA 7 HOH 9 609 121 HOH HOH A . AA 7 HOH 10 610 366 HOH HOH A . AA 7 HOH 11 611 455 HOH HOH A . AA 7 HOH 12 612 191 HOH HOH A . AA 7 HOH 13 613 49 HOH HOH A . AA 7 HOH 14 614 397 HOH HOH A . AA 7 HOH 15 615 494 HOH HOH A . AA 7 HOH 16 616 349 HOH HOH A . AA 7 HOH 17 617 195 HOH HOH A . AA 7 HOH 18 618 471 HOH HOH A . AA 7 HOH 19 619 244 HOH HOH A . AA 7 HOH 20 620 81 HOH HOH A . AA 7 HOH 21 621 105 HOH HOH A . AA 7 HOH 22 622 80 HOH HOH A . AA 7 HOH 23 623 335 HOH HOH A . AA 7 HOH 24 624 11 HOH HOH A . AA 7 HOH 25 625 457 HOH HOH A . AA 7 HOH 26 626 284 HOH HOH A . AA 7 HOH 27 627 320 HOH HOH A . AA 7 HOH 28 628 378 HOH HOH A . AA 7 HOH 29 629 255 HOH HOH A . AA 7 HOH 30 630 327 HOH HOH A . AA 7 HOH 31 631 538 HOH HOH A . AA 7 HOH 32 632 421 HOH HOH A . AA 7 HOH 33 633 464 HOH HOH A . AA 7 HOH 34 634 452 HOH HOH A . AA 7 HOH 35 635 180 HOH HOH A . AA 7 HOH 36 636 229 HOH HOH A . AA 7 HOH 37 637 59 HOH HOH A . AA 7 HOH 38 638 521 HOH HOH A . AA 7 HOH 39 639 250 HOH HOH A . AA 7 HOH 40 640 175 HOH HOH A . AA 7 HOH 41 641 151 HOH HOH A . AA 7 HOH 42 642 84 HOH HOH A . AA 7 HOH 43 643 240 HOH HOH A . AA 7 HOH 44 644 436 HOH HOH A . AA 7 HOH 45 645 48 HOH HOH A . AA 7 HOH 46 646 355 HOH HOH A . AA 7 HOH 47 647 527 HOH HOH A . AA 7 HOH 48 648 143 HOH HOH A . AA 7 HOH 49 649 377 HOH HOH A . AA 7 HOH 50 650 263 HOH HOH A . AA 7 HOH 51 651 225 HOH HOH A . AA 7 HOH 52 652 109 HOH HOH A . AA 7 HOH 53 653 317 HOH HOH A . AA 7 HOH 54 654 14 HOH HOH A . AA 7 HOH 55 655 163 HOH HOH A . AA 7 HOH 56 656 432 HOH HOH A . AA 7 HOH 57 657 20 HOH HOH A . AA 7 HOH 58 658 32 HOH HOH A . AA 7 HOH 59 659 146 HOH HOH A . AA 7 HOH 60 660 173 HOH HOH A . AA 7 HOH 61 661 316 HOH HOH A . AA 7 HOH 62 662 60 HOH HOH A . AA 7 HOH 63 663 71 HOH HOH A . AA 7 HOH 64 664 172 HOH HOH A . AA 7 HOH 65 665 197 HOH HOH A . AA 7 HOH 66 666 208 HOH HOH A . AA 7 HOH 67 667 401 HOH HOH A . AA 7 HOH 68 668 1 HOH HOH A . AA 7 HOH 69 669 101 HOH HOH A . AA 7 HOH 70 670 21 HOH HOH A . AA 7 HOH 71 671 346 HOH HOH A . AA 7 HOH 72 672 27 HOH HOH A . AA 7 HOH 73 673 437 HOH HOH A . AA 7 HOH 74 674 87 HOH HOH A . AA 7 HOH 75 675 53 HOH HOH A . AA 7 HOH 76 676 90 HOH HOH A . AA 7 HOH 77 677 517 HOH HOH A . AA 7 HOH 78 678 246 HOH HOH A . AA 7 HOH 79 679 419 HOH HOH A . AA 7 HOH 80 680 283 HOH HOH A . AA 7 HOH 81 681 183 HOH HOH A . AA 7 HOH 82 682 164 HOH HOH A . AA 7 HOH 83 683 3 HOH HOH A . AA 7 HOH 84 684 65 HOH HOH A . AA 7 HOH 85 685 199 HOH HOH A . AA 7 HOH 86 686 487 HOH HOH A . AA 7 HOH 87 687 276 HOH HOH A . AA 7 HOH 88 688 338 HOH HOH A . AA 7 HOH 89 689 184 HOH HOH A . AA 7 HOH 90 690 130 HOH HOH A . AA 7 HOH 91 691 169 HOH HOH A . AA 7 HOH 92 692 79 HOH HOH A . AA 7 HOH 93 693 384 HOH HOH A . AA 7 HOH 94 694 72 HOH HOH A . AA 7 HOH 95 695 279 HOH HOH A . AA 7 HOH 96 696 24 HOH HOH A . AA 7 HOH 97 697 92 HOH HOH A . AA 7 HOH 98 698 438 HOH HOH A . AA 7 HOH 99 699 157 HOH HOH A . AA 7 HOH 100 700 389 HOH HOH A . AA 7 HOH 101 701 30 HOH HOH A . AA 7 HOH 102 702 224 HOH HOH A . AA 7 HOH 103 703 8 HOH HOH A . AA 7 HOH 104 704 62 HOH HOH A . AA 7 HOH 105 705 359 HOH HOH A . AA 7 HOH 106 706 345 HOH HOH A . AA 7 HOH 107 707 66 HOH HOH A . AA 7 HOH 108 708 463 HOH HOH A . AA 7 HOH 109 709 97 HOH HOH A . AA 7 HOH 110 710 271 HOH HOH A . AA 7 HOH 111 711 230 HOH HOH A . AA 7 HOH 112 712 206 HOH HOH A . AA 7 HOH 113 713 222 HOH HOH A . AA 7 HOH 114 714 118 HOH HOH A . AA 7 HOH 115 715 25 HOH HOH A . AA 7 HOH 116 716 18 HOH HOH A . AA 7 HOH 117 717 54 HOH HOH A . AA 7 HOH 118 718 140 HOH HOH A . AA 7 HOH 119 719 500 HOH HOH A . AA 7 HOH 120 720 313 HOH HOH A . AA 7 HOH 121 721 166 HOH HOH A . AA 7 HOH 122 722 6 HOH HOH A . AA 7 HOH 123 723 77 HOH HOH A . AA 7 HOH 124 724 196 HOH HOH A . AA 7 HOH 125 725 37 HOH HOH A . AA 7 HOH 126 726 128 HOH HOH A . AA 7 HOH 127 727 43 HOH HOH A . AA 7 HOH 128 728 305 HOH HOH A . AA 7 HOH 129 729 141 HOH HOH A . AA 7 HOH 130 730 75 HOH HOH A . AA 7 HOH 131 731 22 HOH HOH A . AA 7 HOH 132 732 86 HOH HOH A . AA 7 HOH 133 733 473 HOH HOH A . AA 7 HOH 134 734 55 HOH HOH A . AA 7 HOH 135 735 402 HOH HOH A . AA 7 HOH 136 736 236 HOH HOH A . AA 7 HOH 137 737 119 HOH HOH A . AA 7 HOH 138 738 156 HOH HOH A . AA 7 HOH 139 739 99 HOH HOH A . AA 7 HOH 140 740 477 HOH HOH A . AA 7 HOH 141 741 266 HOH HOH A . AA 7 HOH 142 742 46 HOH HOH A . AA 7 HOH 143 743 69 HOH HOH A . AA 7 HOH 144 744 460 HOH HOH A . AA 7 HOH 145 745 138 HOH HOH A . AA 7 HOH 146 746 19 HOH HOH A . AA 7 HOH 147 747 188 HOH HOH A . AA 7 HOH 148 748 306 HOH HOH A . AA 7 HOH 149 749 96 HOH HOH A . AA 7 HOH 150 750 488 HOH HOH A . AA 7 HOH 151 751 444 HOH HOH A . AA 7 HOH 152 752 132 HOH HOH A . AA 7 HOH 153 753 68 HOH HOH A . AA 7 HOH 154 754 256 HOH HOH A . AA 7 HOH 155 755 58 HOH HOH A . AA 7 HOH 156 756 176 HOH HOH A . AA 7 HOH 157 757 451 HOH HOH A . AA 7 HOH 158 758 371 HOH HOH A . AA 7 HOH 159 759 526 HOH HOH A . AA 7 HOH 160 760 28 HOH HOH A . AA 7 HOH 161 761 67 HOH HOH A . AA 7 HOH 162 762 466 HOH HOH A . AA 7 HOH 163 763 4 HOH HOH A . AA 7 HOH 164 764 274 HOH HOH A . AA 7 HOH 165 765 519 HOH HOH A . AA 7 HOH 166 766 465 HOH HOH A . AA 7 HOH 167 767 363 HOH HOH A . AA 7 HOH 168 768 221 HOH HOH A . AA 7 HOH 169 769 511 HOH HOH A . AA 7 HOH 170 770 98 HOH HOH A . AA 7 HOH 171 771 231 HOH HOH A . AA 7 HOH 172 772 239 HOH HOH A . AA 7 HOH 173 773 124 HOH HOH A . AA 7 HOH 174 774 63 HOH HOH A . AA 7 HOH 175 775 2 HOH HOH A . AA 7 HOH 176 776 9 HOH HOH A . AA 7 HOH 177 777 115 HOH HOH A . AA 7 HOH 178 778 248 HOH HOH A . AA 7 HOH 179 779 104 HOH HOH A . AA 7 HOH 180 780 470 HOH HOH A . AA 7 HOH 181 781 209 HOH HOH A . AA 7 HOH 182 782 281 HOH HOH A . AA 7 HOH 183 783 439 HOH HOH A . AA 7 HOH 184 784 307 HOH HOH A . AA 7 HOH 185 785 103 HOH HOH A . AA 7 HOH 186 786 155 HOH HOH A . AA 7 HOH 187 787 78 HOH HOH A . AA 7 HOH 188 788 41 HOH HOH A . AA 7 HOH 189 789 64 HOH HOH A . AA 7 HOH 190 790 91 HOH HOH A . AA 7 HOH 191 791 226 HOH HOH A . AA 7 HOH 192 792 186 HOH HOH A . AA 7 HOH 193 793 386 HOH HOH A . AA 7 HOH 194 794 286 HOH HOH A . AA 7 HOH 195 795 333 HOH HOH A . AA 7 HOH 196 796 177 HOH HOH A . AA 7 HOH 197 797 420 HOH HOH A . AA 7 HOH 198 798 88 HOH HOH A . AA 7 HOH 199 799 34 HOH HOH A . AA 7 HOH 200 800 462 HOH HOH A . AA 7 HOH 201 801 289 HOH HOH A . AA 7 HOH 202 802 218 HOH HOH A . AA 7 HOH 203 803 179 HOH HOH A . AA 7 HOH 204 804 467 HOH HOH A . AA 7 HOH 205 805 290 HOH HOH A . AA 7 HOH 206 806 485 HOH HOH A . AA 7 HOH 207 807 425 HOH HOH A . AA 7 HOH 208 808 205 HOH HOH A . AA 7 HOH 209 809 533 HOH HOH A . AA 7 HOH 210 810 360 HOH HOH A . AA 7 HOH 211 811 424 HOH HOH A . AA 7 HOH 212 812 259 HOH HOH A . AA 7 HOH 213 813 251 HOH HOH A . AA 7 HOH 214 814 330 HOH HOH A . AA 7 HOH 215 815 342 HOH HOH A . AA 7 HOH 216 816 443 HOH HOH A . AA 7 HOH 217 817 528 HOH HOH A . AA 7 HOH 218 818 89 HOH HOH A . AA 7 HOH 219 819 135 HOH HOH A . AA 7 HOH 220 820 280 HOH HOH A . AA 7 HOH 221 821 295 HOH HOH A . AA 7 HOH 222 822 70 HOH HOH A . AA 7 HOH 223 823 299 HOH HOH A . AA 7 HOH 224 824 353 HOH HOH A . AA 7 HOH 225 825 534 HOH HOH A . AA 7 HOH 226 826 257 HOH HOH A . AA 7 HOH 227 827 304 HOH HOH A . AA 7 HOH 228 828 287 HOH HOH A . AA 7 HOH 229 829 499 HOH HOH A . AA 7 HOH 230 830 514 HOH HOH A . AA 7 HOH 231 831 93 HOH HOH A . AA 7 HOH 232 832 292 HOH HOH A . AA 7 HOH 233 833 429 HOH HOH A . AA 7 HOH 234 834 337 HOH HOH A . AA 7 HOH 235 835 324 HOH HOH A . AA 7 HOH 236 836 509 HOH HOH A . AA 7 HOH 237 837 365 HOH HOH A . AA 7 HOH 238 838 520 HOH HOH A . AA 7 HOH 239 839 418 HOH HOH A . AA 7 HOH 240 840 328 HOH HOH A . AA 7 HOH 241 841 480 HOH HOH A . AA 7 HOH 242 842 395 HOH HOH A . AA 7 HOH 243 843 482 HOH HOH A . AA 7 HOH 244 844 282 HOH HOH A . AA 7 HOH 245 845 315 HOH HOH A . AA 7 HOH 246 846 513 HOH HOH A . AA 7 HOH 247 847 479 HOH HOH A . AA 7 HOH 248 848 448 HOH HOH A . AA 7 HOH 249 849 481 HOH HOH A . AA 7 HOH 250 850 392 HOH HOH A . AA 7 HOH 251 851 530 HOH HOH A . AA 7 HOH 252 852 486 HOH HOH A . AA 7 HOH 253 853 522 HOH HOH A . AA 7 HOH 254 854 512 HOH HOH A . AA 7 HOH 255 855 265 HOH HOH A . AA 7 HOH 256 856 498 HOH HOH A . AA 7 HOH 257 857 507 HOH HOH A . AA 7 HOH 258 858 506 HOH HOH A . AA 7 HOH 259 859 314 HOH HOH A . AA 7 HOH 260 860 367 HOH HOH A . AA 7 HOH 261 861 264 HOH HOH A . AA 7 HOH 262 862 441 HOH HOH A . AA 7 HOH 263 863 469 HOH HOH A . AA 7 HOH 264 864 212 HOH HOH A . AA 7 HOH 265 865 193 HOH HOH A . AA 7 HOH 266 866 408 HOH HOH A . AA 7 HOH 267 867 404 HOH HOH A . AA 7 HOH 268 868 223 HOH HOH A . AA 7 HOH 269 869 319 HOH HOH A . AA 7 HOH 270 870 102 HOH HOH A . AA 7 HOH 271 871 297 HOH HOH A . AA 7 HOH 272 872 472 HOH HOH A . AA 7 HOH 273 873 233 HOH HOH A . AA 7 HOH 274 874 308 HOH HOH A . AA 7 HOH 275 875 405 HOH HOH A . AA 7 HOH 276 876 235 HOH HOH A . AA 7 HOH 277 877 362 HOH HOH A . AA 7 HOH 278 878 267 HOH HOH A . AA 7 HOH 279 879 347 HOH HOH A . AA 7 HOH 280 880 288 HOH HOH A . AA 7 HOH 281 881 393 HOH HOH A . AA 7 HOH 282 882 497 HOH HOH A . AA 7 HOH 283 883 258 HOH HOH A . AA 7 HOH 284 884 159 HOH HOH A . AA 7 HOH 285 885 211 HOH HOH A . AA 7 HOH 286 886 243 HOH HOH A . AA 7 HOH 287 887 459 HOH HOH A . AA 7 HOH 288 888 326 HOH HOH A . AA 7 HOH 289 889 357 HOH HOH A . AA 7 HOH 290 890 468 HOH HOH A . AA 7 HOH 291 891 376 HOH HOH A . AA 7 HOH 292 892 525 HOH HOH A . AA 7 HOH 293 893 300 HOH HOH A . AA 7 HOH 294 894 399 HOH HOH A . AA 7 HOH 295 895 461 HOH HOH A . BA 7 HOH 1 601 516 HOH HOH B . BA 7 HOH 2 602 505 HOH HOH B . BA 7 HOH 3 603 50 HOH HOH B . BA 7 HOH 4 604 427 HOH HOH B . BA 7 HOH 5 605 524 HOH HOH B . BA 7 HOH 6 606 253 HOH HOH B . BA 7 HOH 7 607 181 HOH HOH B . BA 7 HOH 8 608 380 HOH HOH B . BA 7 HOH 9 609 202 HOH HOH B . BA 7 HOH 10 610 83 HOH HOH B . BA 7 HOH 11 611 139 HOH HOH B . BA 7 HOH 12 612 36 HOH HOH B . BA 7 HOH 13 613 200 HOH HOH B . BA 7 HOH 14 614 310 HOH HOH B . BA 7 HOH 15 615 412 HOH HOH B . BA 7 HOH 16 616 302 HOH HOH B . BA 7 HOH 17 617 430 HOH HOH B . BA 7 HOH 18 618 113 HOH HOH B . BA 7 HOH 19 619 431 HOH HOH B . BA 7 HOH 20 620 382 HOH HOH B . BA 7 HOH 21 621 167 HOH HOH B . BA 7 HOH 22 622 158 HOH HOH B . BA 7 HOH 23 623 396 HOH HOH B . BA 7 HOH 24 624 228 HOH HOH B . BA 7 HOH 25 625 340 HOH HOH B . BA 7 HOH 26 626 532 HOH HOH B . BA 7 HOH 27 627 185 HOH HOH B . BA 7 HOH 28 628 252 HOH HOH B . BA 7 HOH 29 629 518 HOH HOH B . BA 7 HOH 30 630 107 HOH HOH B . BA 7 HOH 31 631 270 HOH HOH B . BA 7 HOH 32 632 398 HOH HOH B . BA 7 HOH 33 633 260 HOH HOH B . BA 7 HOH 34 634 496 HOH HOH B . BA 7 HOH 35 635 29 HOH HOH B . BA 7 HOH 36 636 249 HOH HOH B . BA 7 HOH 37 637 133 HOH HOH B . BA 7 HOH 38 638 85 HOH HOH B . BA 7 HOH 39 639 154 HOH HOH B . BA 7 HOH 40 640 76 HOH HOH B . BA 7 HOH 41 641 56 HOH HOH B . BA 7 HOH 42 642 394 HOH HOH B . BA 7 HOH 43 643 13 HOH HOH B . BA 7 HOH 44 644 322 HOH HOH B . BA 7 HOH 45 645 73 HOH HOH B . BA 7 HOH 46 646 148 HOH HOH B . BA 7 HOH 47 647 82 HOH HOH B . BA 7 HOH 48 648 7 HOH HOH B . BA 7 HOH 49 649 74 HOH HOH B . BA 7 HOH 50 650 268 HOH HOH B . BA 7 HOH 51 651 190 HOH HOH B . BA 7 HOH 52 652 294 HOH HOH B . BA 7 HOH 53 653 52 HOH HOH B . BA 7 HOH 54 654 57 HOH HOH B . BA 7 HOH 55 655 303 HOH HOH B . BA 7 HOH 56 656 38 HOH HOH B . BA 7 HOH 57 657 189 HOH HOH B . BA 7 HOH 58 658 247 HOH HOH B . BA 7 HOH 59 659 168 HOH HOH B . BA 7 HOH 60 660 40 HOH HOH B . BA 7 HOH 61 661 94 HOH HOH B . BA 7 HOH 62 662 238 HOH HOH B . BA 7 HOH 63 663 153 HOH HOH B . BA 7 HOH 64 664 364 HOH HOH B . BA 7 HOH 65 665 51 HOH HOH B . BA 7 HOH 66 666 170 HOH HOH B . BA 7 HOH 67 667 45 HOH HOH B . BA 7 HOH 68 668 207 HOH HOH B . BA 7 HOH 69 669 198 HOH HOH B . BA 7 HOH 70 670 16 HOH HOH B . BA 7 HOH 71 671 456 HOH HOH B . BA 7 HOH 72 672 127 HOH HOH B . BA 7 HOH 73 673 391 HOH HOH B . BA 7 HOH 74 674 134 HOH HOH B . BA 7 HOH 75 675 423 HOH HOH B . BA 7 HOH 76 676 136 HOH HOH B . BA 7 HOH 77 677 106 HOH HOH B . BA 7 HOH 78 678 114 HOH HOH B . BA 7 HOH 79 679 450 HOH HOH B . BA 7 HOH 80 680 39 HOH HOH B . BA 7 HOH 81 681 339 HOH HOH B . BA 7 HOH 82 682 262 HOH HOH B . BA 7 HOH 83 683 277 HOH HOH B . BA 7 HOH 84 684 116 HOH HOH B . BA 7 HOH 85 685 47 HOH HOH B . BA 7 HOH 86 686 336 HOH HOH B . BA 7 HOH 87 687 254 HOH HOH B . BA 7 HOH 88 688 44 HOH HOH B . BA 7 HOH 89 689 150 HOH HOH B . BA 7 HOH 90 690 504 HOH HOH B . BA 7 HOH 91 691 216 HOH HOH B . BA 7 HOH 92 692 220 HOH HOH B . BA 7 HOH 93 693 95 HOH HOH B . BA 7 HOH 94 694 293 HOH HOH B . BA 7 HOH 95 695 145 HOH HOH B . BA 7 HOH 96 696 301 HOH HOH B . BA 7 HOH 97 697 117 HOH HOH B . BA 7 HOH 98 698 351 HOH HOH B . BA 7 HOH 99 699 192 HOH HOH B . BA 7 HOH 100 700 449 HOH HOH B . BA 7 HOH 101 701 210 HOH HOH B . BA 7 HOH 102 702 269 HOH HOH B . BA 7 HOH 103 703 409 HOH HOH B . BA 7 HOH 104 704 242 HOH HOH B . BA 7 HOH 105 705 15 HOH HOH B . BA 7 HOH 106 706 10 HOH HOH B . BA 7 HOH 107 707 33 HOH HOH B . BA 7 HOH 108 708 215 HOH HOH B . BA 7 HOH 109 709 275 HOH HOH B . BA 7 HOH 110 710 410 HOH HOH B . BA 7 HOH 111 711 125 HOH HOH B . BA 7 HOH 112 712 403 HOH HOH B . BA 7 HOH 113 713 26 HOH HOH B . BA 7 HOH 114 714 318 HOH HOH B . BA 7 HOH 115 715 142 HOH HOH B . BA 7 HOH 116 716 42 HOH HOH B . BA 7 HOH 117 717 160 HOH HOH B . BA 7 HOH 118 718 131 HOH HOH B . BA 7 HOH 119 719 108 HOH HOH B . BA 7 HOH 120 720 312 HOH HOH B . BA 7 HOH 121 721 152 HOH HOH B . BA 7 HOH 122 722 17 HOH HOH B . BA 7 HOH 123 723 149 HOH HOH B . BA 7 HOH 124 724 234 HOH HOH B . BA 7 HOH 125 725 358 HOH HOH B . BA 7 HOH 126 726 478 HOH HOH B . BA 7 HOH 127 727 162 HOH HOH B . BA 7 HOH 128 728 178 HOH HOH B . BA 7 HOH 129 729 35 HOH HOH B . BA 7 HOH 130 730 232 HOH HOH B . BA 7 HOH 131 731 535 HOH HOH B . BA 7 HOH 132 732 311 HOH HOH B . BA 7 HOH 133 733 361 HOH HOH B . BA 7 HOH 134 734 356 HOH HOH B . BA 7 HOH 135 735 111 HOH HOH B . BA 7 HOH 136 736 375 HOH HOH B . BA 7 HOH 137 737 137 HOH HOH B . BA 7 HOH 138 738 201 HOH HOH B . BA 7 HOH 139 739 129 HOH HOH B . BA 7 HOH 140 740 144 HOH HOH B . BA 7 HOH 141 741 285 HOH HOH B . BA 7 HOH 142 742 489 HOH HOH B . BA 7 HOH 143 743 354 HOH HOH B . BA 7 HOH 144 744 334 HOH HOH B . BA 7 HOH 145 745 126 HOH HOH B . BA 7 HOH 146 746 484 HOH HOH B . BA 7 HOH 147 747 536 HOH HOH B . BA 7 HOH 148 748 323 HOH HOH B . BA 7 HOH 149 749 332 HOH HOH B . BA 7 HOH 150 750 508 HOH HOH B . BA 7 HOH 151 751 100 HOH HOH B . BA 7 HOH 152 752 203 HOH HOH B . BA 7 HOH 153 753 350 HOH HOH B . BA 7 HOH 154 754 321 HOH HOH B . BA 7 HOH 155 755 537 HOH HOH B . BA 7 HOH 156 756 374 HOH HOH B . BA 7 HOH 157 757 123 HOH HOH B . BA 7 HOH 158 758 194 HOH HOH B . BA 7 HOH 159 759 341 HOH HOH B . BA 7 HOH 160 760 120 HOH HOH B . BA 7 HOH 161 761 414 HOH HOH B . BA 7 HOH 162 762 491 HOH HOH B . BA 7 HOH 163 763 182 HOH HOH B . BA 7 HOH 164 764 539 HOH HOH B . BA 7 HOH 165 765 453 HOH HOH B . BA 7 HOH 166 766 372 HOH HOH B . BA 7 HOH 167 767 187 HOH HOH B . BA 7 HOH 168 768 406 HOH HOH B . BA 7 HOH 169 769 241 HOH HOH B . BA 7 HOH 170 770 387 HOH HOH B . BA 7 HOH 171 771 531 HOH HOH B . BA 7 HOH 172 772 214 HOH HOH B . BA 7 HOH 173 773 388 HOH HOH B . BA 7 HOH 174 774 510 HOH HOH B . BA 7 HOH 175 775 213 HOH HOH B . BA 7 HOH 176 776 344 HOH HOH B . BA 7 HOH 177 777 227 HOH HOH B . BA 7 HOH 178 778 245 HOH HOH B . BA 7 HOH 179 779 204 HOH HOH B . BA 7 HOH 180 780 61 HOH HOH B . BA 7 HOH 181 781 112 HOH HOH B . BA 7 HOH 182 782 171 HOH HOH B . BA 7 HOH 183 783 165 HOH HOH B . BA 7 HOH 184 784 325 HOH HOH B . BA 7 HOH 185 785 161 HOH HOH B . BA 7 HOH 186 786 370 HOH HOH B . BA 7 HOH 187 787 433 HOH HOH B . BA 7 HOH 188 788 174 HOH HOH B . BA 7 HOH 189 789 147 HOH HOH B . BA 7 HOH 190 790 492 HOH HOH B . BA 7 HOH 191 791 309 HOH HOH B . BA 7 HOH 192 792 298 HOH HOH B . BA 7 HOH 193 793 416 HOH HOH B . BA 7 HOH 194 794 435 HOH HOH B . BA 7 HOH 195 795 490 HOH HOH B . BA 7 HOH 196 796 383 HOH HOH B . BA 7 HOH 197 797 348 HOH HOH B . BA 7 HOH 198 798 529 HOH HOH B . BA 7 HOH 199 799 237 HOH HOH B . BA 7 HOH 200 800 501 HOH HOH B . BA 7 HOH 201 801 523 HOH HOH B . BA 7 HOH 202 802 413 HOH HOH B . BA 7 HOH 203 803 390 HOH HOH B . BA 7 HOH 204 804 446 HOH HOH B . BA 7 HOH 205 805 503 HOH HOH B . BA 7 HOH 206 806 440 HOH HOH B . BA 7 HOH 207 807 219 HOH HOH B . BA 7 HOH 208 808 434 HOH HOH B . BA 7 HOH 209 809 442 HOH HOH B . BA 7 HOH 210 810 217 HOH HOH B . BA 7 HOH 211 811 476 HOH HOH B . BA 7 HOH 212 812 352 HOH HOH B . BA 7 HOH 213 813 502 HOH HOH B . BA 7 HOH 214 814 296 HOH HOH B . BA 7 HOH 215 815 400 HOH HOH B . BA 7 HOH 216 816 273 HOH HOH B . BA 7 HOH 217 817 475 HOH HOH B . BA 7 HOH 218 818 261 HOH HOH B . BA 7 HOH 219 819 329 HOH HOH B . BA 7 HOH 220 820 454 HOH HOH B . BA 7 HOH 221 821 411 HOH HOH B . BA 7 HOH 222 822 291 HOH HOH B . BA 7 HOH 223 823 369 HOH HOH B . BA 7 HOH 224 824 368 HOH HOH B . BA 7 HOH 225 825 515 HOH HOH B . BA 7 HOH 226 826 495 HOH HOH B . BA 7 HOH 227 827 122 HOH HOH B . BA 7 HOH 228 828 474 HOH HOH B . BA 7 HOH 229 829 343 HOH HOH B . BA 7 HOH 230 830 458 HOH HOH B . BA 7 HOH 231 831 445 HOH HOH B . BA 7 HOH 232 832 373 HOH HOH B . BA 7 HOH 233 833 483 HOH HOH B . # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA monomeric 1 2 author_and_software_defined_assembly PISA monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,C,D,E,F,G,H,I,J,K,L,M,N,O,AA 2 1 B,P,Q,R,S,T,U,V,W,X,Y,Z,BA # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 2110 ? 1 MORE -31 ? 1 'SSA (A^2)' 16130 ? 2 'ABSA (A^2)' 1950 ? 2 MORE -33 ? 2 'SSA (A^2)' 15950 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 OD1 ? A ASP 32 ? A ASP 32 ? 1_555 ZN ? K ZN . ? A ZN 509 ? 1_555 OG ? A SER 71 ? A SER 71 ? 1_555 123.3 ? 2 OD1 ? A ASP 32 ? A ASP 32 ? 1_555 ZN ? K ZN . ? A ZN 509 ? 1_555 OD2 ? A ASP 240 ? A ASP 240 ? 1_555 101.7 ? 3 OG ? A SER 71 ? A SER 71 ? 1_555 ZN ? K ZN . ? A ZN 509 ? 1_555 OD2 ? A ASP 240 ? A ASP 240 ? 1_555 79.8 ? 4 OD1 ? A ASP 32 ? A ASP 32 ? 1_555 ZN ? K ZN . ? A ZN 509 ? 1_555 NE2 ? A HIS 241 ? A HIS 241 ? 1_555 114.3 ? 5 OG ? A SER 71 ? A SER 71 ? 1_555 ZN ? K ZN . ? A ZN 509 ? 1_555 NE2 ? A HIS 241 ? A HIS 241 ? 1_555 122.3 ? 6 OD2 ? A ASP 240 ? A ASP 240 ? 1_555 ZN ? K ZN . ? A ZN 509 ? 1_555 NE2 ? A HIS 241 ? A HIS 241 ? 1_555 91.7 ? 7 OD1 ? A ASP 32 ? A ASP 32 ? 1_555 ZN ? K ZN . ? A ZN 509 ? 1_555 O3 ? N PC . ? A PC 512 ? 1_555 105.4 ? 8 OG ? A SER 71 ? A SER 71 ? 1_555 ZN ? K ZN . ? A ZN 509 ? 1_555 O3 ? N PC . ? A PC 512 ? 1_555 66.1 ? 9 OD2 ? A ASP 240 ? A ASP 240 ? 1_555 ZN ? K ZN . ? A ZN 509 ? 1_555 O3 ? N PC . ? A PC 512 ? 1_555 144.3 ? 10 NE2 ? A HIS 241 ? A HIS 241 ? 1_555 ZN ? K ZN . ? A ZN 509 ? 1_555 O3 ? N PC . ? A PC 512 ? 1_555 97.7 ? 11 OD1 ? A ASP 193 ? A ASP 193 ? 1_555 ZN ? J ZN . ? A ZN 508 ? 1_555 OD2 ? A ASP 193 ? A ASP 193 ? 1_555 53.3 ? 12 OD1 ? A ASP 193 ? A ASP 193 ? 1_555 ZN ? J ZN . ? A ZN 508 ? 1_555 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 101.0 ? 13 OD2 ? A ASP 193 ? A ASP 193 ? 1_555 ZN ? J ZN . ? A ZN 508 ? 1_555 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 97.0 ? 14 OD1 ? A ASP 193 ? A ASP 193 ? 1_555 ZN ? J ZN . ? A ZN 508 ? 1_555 NE2 ? A HIS 354 ? A HIS 354 ? 1_555 95.5 ? 15 OD2 ? A ASP 193 ? A ASP 193 ? 1_555 ZN ? J ZN . ? A ZN 508 ? 1_555 NE2 ? A HIS 354 ? A HIS 354 ? 1_555 146.0 ? 16 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 ZN ? J ZN . ? A ZN 508 ? 1_555 NE2 ? A HIS 354 ? A HIS 354 ? 1_555 102.8 ? 17 OD1 ? A ASP 193 ? A ASP 193 ? 1_555 ZN ? J ZN . ? A ZN 508 ? 1_555 O1 ? N PC . ? A PC 512 ? 1_555 143.6 ? 18 OD2 ? A ASP 193 ? A ASP 193 ? 1_555 ZN ? J ZN . ? A ZN 508 ? 1_555 O1 ? N PC . ? A PC 512 ? 1_555 102.9 ? 19 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 ZN ? J ZN . ? A ZN 508 ? 1_555 O1 ? N PC . ? A PC 512 ? 1_555 109.9 ? 20 NE2 ? A HIS 354 ? A HIS 354 ? 1_555 ZN ? J ZN . ? A ZN 508 ? 1_555 O1 ? N PC . ? A PC 512 ? 1_555 96.1 ? 21 OD1 ? B ASP 32 ? B ASP 32 ? 1_555 ZN ? V ZN . ? B ZN 507 ? 1_555 OG ? B SER 71 ? B SER 71 ? 1_555 125.2 ? 22 OD1 ? B ASP 32 ? B ASP 32 ? 1_555 ZN ? V ZN . ? B ZN 507 ? 1_555 OD2 ? B ASP 240 ? B ASP 240 ? 1_555 105.3 ? 23 OG ? B SER 71 ? B SER 71 ? 1_555 ZN ? V ZN . ? B ZN 507 ? 1_555 OD2 ? B ASP 240 ? B ASP 240 ? 1_555 80.0 ? 24 OD1 ? B ASP 32 ? B ASP 32 ? 1_555 ZN ? V ZN . ? B ZN 507 ? 1_555 NE2 ? B HIS 241 ? B HIS 241 ? 1_555 112.9 ? 25 OG ? B SER 71 ? B SER 71 ? 1_555 ZN ? V ZN . ? B ZN 507 ? 1_555 NE2 ? B HIS 241 ? B HIS 241 ? 1_555 121.8 ? 26 OD2 ? B ASP 240 ? B ASP 240 ? 1_555 ZN ? V ZN . ? B ZN 507 ? 1_555 NE2 ? B HIS 241 ? B HIS 241 ? 1_555 87.9 ? 27 OD1 ? B ASP 32 ? B ASP 32 ? 1_555 ZN ? V ZN . ? B ZN 507 ? 1_555 O4 ? Y PC . ? B PC 510 ? 1_555 100.3 ? 28 OG ? B SER 71 ? B SER 71 ? 1_555 ZN ? V ZN . ? B ZN 507 ? 1_555 O4 ? Y PC . ? B PC 510 ? 1_555 66.8 ? 29 OD2 ? B ASP 240 ? B ASP 240 ? 1_555 ZN ? V ZN . ? B ZN 507 ? 1_555 O4 ? Y PC . ? B PC 510 ? 1_555 145.9 ? 30 NE2 ? B HIS 241 ? B HIS 241 ? 1_555 ZN ? V ZN . ? B ZN 507 ? 1_555 O4 ? Y PC . ? B PC 510 ? 1_555 102.6 ? 31 OD1 ? B ASP 193 ? B ASP 193 ? 1_555 ZN ? W ZN . ? B ZN 508 ? 1_555 OD2 ? B ASP 193 ? B ASP 193 ? 1_555 54.5 ? 32 OD1 ? B ASP 193 ? B ASP 193 ? 1_555 ZN ? W ZN . ? B ZN 508 ? 1_555 NE2 ? B HIS 197 ? B HIS 197 ? 1_555 101.7 ? 33 OD2 ? B ASP 193 ? B ASP 193 ? 1_555 ZN ? W ZN . ? B ZN 508 ? 1_555 NE2 ? B HIS 197 ? B HIS 197 ? 1_555 99.0 ? 34 OD1 ? B ASP 193 ? B ASP 193 ? 1_555 ZN ? W ZN . ? B ZN 508 ? 1_555 NE2 ? B HIS 354 ? B HIS 354 ? 1_555 97.4 ? 35 OD2 ? B ASP 193 ? B ASP 193 ? 1_555 ZN ? W ZN . ? B ZN 508 ? 1_555 NE2 ? B HIS 354 ? B HIS 354 ? 1_555 147.6 ? 36 NE2 ? B HIS 197 ? B HIS 197 ? 1_555 ZN ? W ZN . ? B ZN 508 ? 1_555 NE2 ? B HIS 354 ? B HIS 354 ? 1_555 102.9 ? 37 OD1 ? B ASP 193 ? B ASP 193 ? 1_555 ZN ? W ZN . ? B ZN 508 ? 1_555 O3 ? Y PC . ? B PC 510 ? 1_555 145.0 ? 38 OD2 ? B ASP 193 ? B ASP 193 ? 1_555 ZN ? W ZN . ? B ZN 508 ? 1_555 O3 ? Y PC . ? B PC 510 ? 1_555 101.3 ? 39 NE2 ? B HIS 197 ? B HIS 197 ? 1_555 ZN ? W ZN . ? B ZN 508 ? 1_555 O3 ? Y PC . ? B PC 510 ? 1_555 107.3 ? 40 NE2 ? B HIS 354 ? B HIS 354 ? 1_555 ZN ? W ZN . ? B ZN 508 ? 1_555 O3 ? Y PC . ? B PC 510 ? 1_555 94.7 ? # _pdbx_audit_revision_history.ordinal 1 _pdbx_audit_revision_history.data_content_type 'Structure model' _pdbx_audit_revision_history.major_revision 1 _pdbx_audit_revision_history.minor_revision 0 _pdbx_audit_revision_history.revision_date 2016-03-09 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(1.10_2155: ???)' 1 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? XSCALE ? ? ? . 2 ? phasing ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? . 3 ? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot ? ? ? . 4 ? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? 3.15 5 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 O A HOH 735 ? ? O A HOH 752 ? ? 2.00 2 1 O A HOH 735 ? ? O A HOH 815 ? ? 2.01 3 1 O A HOH 614 ? ? O A HOH 628 ? ? 2.09 4 1 O A HOH 769 ? ? O A HOH 845 ? ? 2.10 5 1 O2 B EDO 509 ? ? O B HOH 601 ? ? 2.11 6 1 O A HOH 645 ? ? O A HOH 852 ? ? 2.14 7 1 O A HOH 639 ? ? O A HOH 764 ? ? 2.16 8 1 O B HOH 620 ? ? O B HOH 682 ? ? 2.16 9 1 O B HOH 736 ? ? O B HOH 829 ? ? 2.16 10 1 O4 B NAG 501 ? ? O B HOH 602 ? ? 2.16 11 1 O A TRP 248 ? ? O A HOH 601 ? ? 2.17 12 1 O A HOH 698 ? ? O A HOH 766 ? ? 2.18 13 1 O B HOH 675 ? ? O B HOH 800 ? ? 2.18 14 1 OD1 A ASP 110 ? ? O A HOH 602 ? ? 2.19 15 1 O A HOH 866 ? ? O A HOH 873 ? ? 2.19 # _pdbx_validate_symm_contact.id 1 _pdbx_validate_symm_contact.PDB_model_num 1 _pdbx_validate_symm_contact.auth_atom_id_1 O _pdbx_validate_symm_contact.auth_asym_id_1 A _pdbx_validate_symm_contact.auth_comp_id_1 HOH _pdbx_validate_symm_contact.auth_seq_id_1 656 _pdbx_validate_symm_contact.PDB_ins_code_1 ? _pdbx_validate_symm_contact.label_alt_id_1 ? _pdbx_validate_symm_contact.site_symmetry_1 1_555 _pdbx_validate_symm_contact.auth_atom_id_2 O _pdbx_validate_symm_contact.auth_asym_id_2 B _pdbx_validate_symm_contact.auth_comp_id_2 HOH _pdbx_validate_symm_contact.auth_seq_id_2 762 _pdbx_validate_symm_contact.PDB_ins_code_2 ? _pdbx_validate_symm_contact.label_alt_id_2 ? _pdbx_validate_symm_contact.site_symmetry_2 1_464 _pdbx_validate_symm_contact.dist 2.14 # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 CA _pdbx_validate_rmsd_angle.auth_asym_id_1 B _pdbx_validate_rmsd_angle.auth_comp_id_1 CYS _pdbx_validate_rmsd_angle.auth_seq_id_1 142 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 CB _pdbx_validate_rmsd_angle.auth_asym_id_2 B _pdbx_validate_rmsd_angle.auth_comp_id_2 CYS _pdbx_validate_rmsd_angle.auth_seq_id_2 142 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 SG _pdbx_validate_rmsd_angle.auth_asym_id_3 B _pdbx_validate_rmsd_angle.auth_comp_id_3 CYS _pdbx_validate_rmsd_angle.auth_seq_id_3 142 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 121.43 _pdbx_validate_rmsd_angle.angle_target_value 114.20 _pdbx_validate_rmsd_angle.angle_deviation 7.23 _pdbx_validate_rmsd_angle.angle_standard_deviation 1.10 _pdbx_validate_rmsd_angle.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 SER A 71 ? ? -62.45 -72.90 2 1 GLN A 88 ? ? 84.85 -6.81 3 1 LYS A 158 ? ? -121.53 -64.92 4 1 HIS A 241 ? ? 179.43 172.03 5 1 LYS A 251 ? ? -102.92 52.64 6 1 ASP A 269 ? ? 78.41 170.92 7 1 ASP A 357 ? ? -28.35 122.09 8 1 SER B 71 ? ? -62.45 -76.63 9 1 GLN B 88 ? ? 85.07 -8.36 10 1 LYS B 158 ? ? -122.39 -66.23 11 1 ASP B 269 ? ? 72.68 159.35 12 1 TYR B 310 ? ? -130.86 -30.12 13 1 ASP B 357 ? ? -23.43 121.47 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A GLU 302 ? CG ? A GLU 302 CG 2 1 Y 1 A GLU 302 ? CD ? A GLU 302 CD 3 1 Y 1 A GLU 302 ? OE1 ? A GLU 302 OE1 4 1 Y 1 A GLU 302 ? OE2 ? A GLU 302 OE2 5 1 Y 1 A LYS 345 ? CG ? A LYS 345 CG 6 1 Y 1 A LYS 345 ? CD ? A LYS 345 CD 7 1 Y 1 A LYS 345 ? CE ? A LYS 345 CE 8 1 Y 1 A LYS 345 ? NZ ? A LYS 345 NZ 9 1 Y 1 B HIS 23 ? CG ? B HIS 23 CG 10 1 Y 1 B HIS 23 ? ND1 ? B HIS 23 ND1 11 1 Y 1 B HIS 23 ? CD2 ? B HIS 23 CD2 12 1 Y 1 B HIS 23 ? CE1 ? B HIS 23 CE1 13 1 Y 1 B HIS 23 ? NE2 ? B HIS 23 NE2 14 1 Y 1 B GLU 334 ? CG ? B GLU 334 CG 15 1 Y 1 B GLU 334 ? CD ? B GLU 334 CD 16 1 Y 1 B GLU 334 ? OE1 ? B GLU 334 OE1 17 1 Y 1 B GLU 334 ? OE2 ? B GLU 334 OE2 18 1 Y 1 B LYS 345 ? CG ? B LYS 345 CG 19 1 Y 1 B LYS 345 ? CD ? B LYS 345 CD 20 1 Y 1 B LYS 345 ? CE ? B LYS 345 CE 21 1 Y 1 B LYS 345 ? NZ ? B LYS 345 NZ # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A MET 1 ? A MET 1 2 1 Y 1 A ALA 2 ? A ALA 2 3 1 Y 1 A ALA 3 ? A ALA 3 4 1 Y 1 A LYS 4 ? A LYS 4 5 1 Y 1 A LEU 5 ? A LEU 5 6 1 Y 1 A TRP 6 ? A TRP 6 7 1 Y 1 A THR 7 ? A THR 7 8 1 Y 1 A PHE 8 ? A PHE 8 9 1 Y 1 A LEU 9 ? A LEU 9 10 1 Y 1 A LEU 10 ? A LEU 10 11 1 Y 1 A GLY 11 ? A GLY 11 12 1 Y 1 A PHE 12 ? A PHE 12 13 1 Y 1 A GLY 13 ? A GLY 13 14 1 Y 1 A LEU 14 ? A LEU 14 15 1 Y 1 A SER 15 ? A SER 15 16 1 Y 1 A TRP 16 ? A TRP 16 17 1 Y 1 A VAL 17 ? A VAL 17 18 1 Y 1 A TRP 18 ? A TRP 18 19 1 Y 1 A PRO 19 ? A PRO 19 20 1 Y 1 A ALA 20 ? A ALA 20 21 1 Y 1 A SER 21 ? A SER 21 22 1 Y 1 A ALA 22 ? A ALA 22 23 1 Y 1 A HIS 23 ? A HIS 23 24 1 Y 1 A GLY 416 ? A GLY 416 25 1 Y 1 A GLN 417 ? A GLN 417 26 1 Y 1 A THR 418 ? A THR 418 27 1 Y 1 A SER 419 ? A SER 419 28 1 Y 1 A SER 420 ? A SER 420 29 1 Y 1 A ALA 421 ? A ALA 421 30 1 Y 1 A SER 422 ? A SER 422 31 1 Y 1 A ARG 423 ? A ARG 423 32 1 Y 1 A GLU 424 ? A GLU 424 33 1 Y 1 A ASN 425 ? A ASN 425 34 1 Y 1 A LEU 426 ? A LEU 426 35 1 Y 1 A TYR 427 ? A TYR 427 36 1 Y 1 A PHE 428 ? A PHE 428 37 1 Y 1 A GLN 429 ? A GLN 429 38 1 Y 1 B MET 1 ? B MET 1 39 1 Y 1 B ALA 2 ? B ALA 2 40 1 Y 1 B ALA 3 ? B ALA 3 41 1 Y 1 B LYS 4 ? B LYS 4 42 1 Y 1 B LEU 5 ? B LEU 5 43 1 Y 1 B TRP 6 ? B TRP 6 44 1 Y 1 B THR 7 ? B THR 7 45 1 Y 1 B PHE 8 ? B PHE 8 46 1 Y 1 B LEU 9 ? B LEU 9 47 1 Y 1 B LEU 10 ? B LEU 10 48 1 Y 1 B GLY 11 ? B GLY 11 49 1 Y 1 B PHE 12 ? B PHE 12 50 1 Y 1 B GLY 13 ? B GLY 13 51 1 Y 1 B LEU 14 ? B LEU 14 52 1 Y 1 B SER 15 ? B SER 15 53 1 Y 1 B TRP 16 ? B TRP 16 54 1 Y 1 B VAL 17 ? B VAL 17 55 1 Y 1 B TRP 18 ? B TRP 18 56 1 Y 1 B PRO 19 ? B PRO 19 57 1 Y 1 B ALA 20 ? B ALA 20 58 1 Y 1 B SER 21 ? B SER 21 59 1 Y 1 B ALA 22 ? B ALA 22 60 1 Y 1 B GLY 416 ? B GLY 416 61 1 Y 1 B GLN 417 ? B GLN 417 62 1 Y 1 B THR 418 ? B THR 418 63 1 Y 1 B SER 419 ? B SER 419 64 1 Y 1 B SER 420 ? B SER 420 65 1 Y 1 B ALA 421 ? B ALA 421 66 1 Y 1 B SER 422 ? B SER 422 67 1 Y 1 B ARG 423 ? B ARG 423 68 1 Y 1 B GLU 424 ? B GLU 424 69 1 Y 1 B ASN 425 ? B ASN 425 70 1 Y 1 B LEU 426 ? B LEU 426 71 1 Y 1 B TYR 427 ? B TYR 427 72 1 Y 1 B PHE 428 ? B PHE 428 73 1 Y 1 B GLN 429 ? B GLN 429 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 BETA-L-FUCOSE FUL 4 'ZINC ION' ZN 5 1,2-ETHANEDIOL EDO 6 PHOSPHOCHOLINE PC 7 water HOH #