data_5EBB # _entry.id 5EBB # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5EBB WWPDB D_1000214644 # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5EBB _pdbx_database_status.recvd_initial_deposition_date 2015-10-19 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBE _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Lim, S.M.' 1 'Yeung, K.' 2 'Tresaugues, L.' 3 'Teo, H.L.' 4 'Nordlund, P.' 5 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country UK _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'Febs J.' _citation.journal_id_ASTM ? _citation.journal_id_CSD ? _citation.journal_id_ISSN 1742-464X _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 283 _citation.language ? _citation.page_first 1107 _citation.page_last 1123 _citation.title ;The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a - an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity. ; _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1111/febs.13655 _citation.pdbx_database_id_PubMed 26783088 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Lim, S.M.' 1 primary 'Yeung, K.' 2 primary 'Tresaugues, L.' 3 primary 'Ling, T.H.' 4 primary 'Nordlund, P.' 5 # _cell.entry_id 5EBB _cell.length_a 147.790 _cell.length_b 147.790 _cell.length_c 139.900 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 120.00 _cell.Z_PDB 18 _cell.pdbx_unique_axis ? # _symmetry.entry_id 5EBB _symmetry.space_group_name_H-M 'P 32 2 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 154 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Acid sphingomyelinase-like phosphodiesterase 3a' 46611.406 3 3.1.4.- ? 'UNP residues 34-433' ? 2 non-polymer syn 'ZINC ION' 65.409 6 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 9 ? ? ? ? 4 non-polymer syn 'MALONATE ION' 102.046 3 ? ? ? ? 5 non-polymer syn GLYCEROL 92.094 2 ? ? ? ? 6 water nat water 18.015 301 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'ASM-like phosphodiesterase 3a' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;PPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPP HVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFY SQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNE KLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQY YLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAIM NLDNISYADC ; _entity_poly.pdbx_seq_one_letter_code_can ;PPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPP HVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFY SQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNE KLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQY YLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAIM NLDNISYADC ; _entity_poly.pdbx_strand_id A,B,C _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 PRO n 1 2 PRO n 1 3 ALA n 1 4 ILE n 1 5 GLY n 1 6 GLN n 1 7 PHE n 1 8 TRP n 1 9 HIS n 1 10 VAL n 1 11 THR n 1 12 ASP n 1 13 LEU n 1 14 HIS n 1 15 LEU n 1 16 ASP n 1 17 PRO n 1 18 THR n 1 19 TYR n 1 20 HIS n 1 21 ILE n 1 22 THR n 1 23 ASP n 1 24 ASP n 1 25 HIS n 1 26 THR n 1 27 LYS n 1 28 VAL n 1 29 CYS n 1 30 ALA n 1 31 SER n 1 32 SER n 1 33 LYS n 1 34 GLY n 1 35 ALA n 1 36 ASN n 1 37 ALA n 1 38 SER n 1 39 ASN n 1 40 PRO n 1 41 GLY n 1 42 PRO n 1 43 PHE n 1 44 GLY n 1 45 ASP n 1 46 VAL n 1 47 LEU n 1 48 CYS n 1 49 ASP n 1 50 SER n 1 51 PRO n 1 52 TYR n 1 53 GLN n 1 54 LEU n 1 55 ILE n 1 56 LEU n 1 57 SER n 1 58 ALA n 1 59 PHE n 1 60 ASP n 1 61 PHE n 1 62 ILE n 1 63 LYS n 1 64 ASN n 1 65 SER n 1 66 GLY n 1 67 GLN n 1 68 GLU n 1 69 ALA n 1 70 SER n 1 71 PHE n 1 72 MET n 1 73 ILE n 1 74 TRP n 1 75 THR n 1 76 GLY n 1 77 ASP n 1 78 SER n 1 79 PRO n 1 80 PRO n 1 81 HIS n 1 82 VAL n 1 83 PRO n 1 84 VAL n 1 85 PRO n 1 86 GLU n 1 87 LEU n 1 88 SER n 1 89 THR n 1 90 ASP n 1 91 THR n 1 92 VAL n 1 93 ILE n 1 94 ASN n 1 95 VAL n 1 96 ILE n 1 97 THR n 1 98 ASN n 1 99 MET n 1 100 THR n 1 101 THR n 1 102 THR n 1 103 ILE n 1 104 GLN n 1 105 SER n 1 106 LEU n 1 107 PHE n 1 108 PRO n 1 109 ASN n 1 110 LEU n 1 111 GLN n 1 112 VAL n 1 113 PHE n 1 114 PRO n 1 115 ALA n 1 116 LEU n 1 117 GLY n 1 118 ASN n 1 119 HIS n 1 120 ASP n 1 121 TYR n 1 122 TRP n 1 123 PRO n 1 124 GLN n 1 125 ASP n 1 126 GLN n 1 127 LEU n 1 128 PRO n 1 129 VAL n 1 130 VAL n 1 131 THR n 1 132 SER n 1 133 LYS n 1 134 VAL n 1 135 TYR n 1 136 ASN n 1 137 ALA n 1 138 VAL n 1 139 ALA n 1 140 ASN n 1 141 LEU n 1 142 TRP n 1 143 LYS n 1 144 PRO n 1 145 TRP n 1 146 LEU n 1 147 ASP n 1 148 GLU n 1 149 GLU n 1 150 ALA n 1 151 ILE n 1 152 SER n 1 153 THR n 1 154 LEU n 1 155 ARG n 1 156 LYS n 1 157 GLY n 1 158 GLY n 1 159 PHE n 1 160 TYR n 1 161 SER n 1 162 GLN n 1 163 LYS n 1 164 VAL n 1 165 THR n 1 166 THR n 1 167 ASN n 1 168 PRO n 1 169 ASN n 1 170 LEU n 1 171 ARG n 1 172 ILE n 1 173 ILE n 1 174 SER n 1 175 LEU n 1 176 ASN n 1 177 THR n 1 178 ASN n 1 179 LEU n 1 180 TYR n 1 181 TYR n 1 182 GLY n 1 183 PRO n 1 184 ASN n 1 185 ILE n 1 186 MET n 1 187 THR n 1 188 LEU n 1 189 ASN n 1 190 LYS n 1 191 THR n 1 192 ASP n 1 193 PRO n 1 194 ALA n 1 195 ASN n 1 196 GLN n 1 197 PHE n 1 198 GLU n 1 199 TRP n 1 200 LEU n 1 201 GLU n 1 202 SER n 1 203 THR n 1 204 LEU n 1 205 ASN n 1 206 ASN n 1 207 SER n 1 208 GLN n 1 209 GLN n 1 210 ASN n 1 211 LYS n 1 212 GLU n 1 213 LYS n 1 214 VAL n 1 215 TYR n 1 216 ILE n 1 217 ILE n 1 218 ALA n 1 219 HIS n 1 220 VAL n 1 221 PRO n 1 222 VAL n 1 223 GLY n 1 224 TYR n 1 225 LEU n 1 226 PRO n 1 227 SER n 1 228 SER n 1 229 GLN n 1 230 ASN n 1 231 ILE n 1 232 THR n 1 233 ALA n 1 234 MET n 1 235 ARG n 1 236 GLU n 1 237 TYR n 1 238 TYR n 1 239 ASN n 1 240 GLU n 1 241 LYS n 1 242 LEU n 1 243 ILE n 1 244 ASP n 1 245 ILE n 1 246 PHE n 1 247 GLN n 1 248 LYS n 1 249 TYR n 1 250 SER n 1 251 ASP n 1 252 VAL n 1 253 ILE n 1 254 ALA n 1 255 GLY n 1 256 GLN n 1 257 PHE n 1 258 TYR n 1 259 GLY n 1 260 HIS n 1 261 THR n 1 262 HIS n 1 263 ARG n 1 264 ASP n 1 265 SER n 1 266 ILE n 1 267 MET n 1 268 VAL n 1 269 LEU n 1 270 SER n 1 271 ASP n 1 272 LYS n 1 273 LYS n 1 274 GLY n 1 275 SER n 1 276 PRO n 1 277 VAL n 1 278 ASN n 1 279 SER n 1 280 LEU n 1 281 PHE n 1 282 VAL n 1 283 ALA n 1 284 PRO n 1 285 ALA n 1 286 VAL n 1 287 THR n 1 288 PRO n 1 289 VAL n 1 290 LYS n 1 291 SER n 1 292 VAL n 1 293 LEU n 1 294 GLU n 1 295 LYS n 1 296 GLN n 1 297 THR n 1 298 ASN n 1 299 ASN n 1 300 PRO n 1 301 GLY n 1 302 ILE n 1 303 ARG n 1 304 LEU n 1 305 PHE n 1 306 GLN n 1 307 TYR n 1 308 ASP n 1 309 PRO n 1 310 ARG n 1 311 ASP n 1 312 TYR n 1 313 LYS n 1 314 LEU n 1 315 LEU n 1 316 ASP n 1 317 MET n 1 318 LEU n 1 319 GLN n 1 320 TYR n 1 321 TYR n 1 322 LEU n 1 323 ASN n 1 324 LEU n 1 325 THR n 1 326 GLU n 1 327 ALA n 1 328 ASN n 1 329 LEU n 1 330 LYS n 1 331 GLY n 1 332 GLU n 1 333 SER n 1 334 ILE n 1 335 TRP n 1 336 LYS n 1 337 LEU n 1 338 GLU n 1 339 TYR n 1 340 ILE n 1 341 LEU n 1 342 THR n 1 343 GLN n 1 344 THR n 1 345 TYR n 1 346 ASP n 1 347 ILE n 1 348 GLU n 1 349 ASP n 1 350 LEU n 1 351 GLN n 1 352 PRO n 1 353 GLU n 1 354 SER n 1 355 LEU n 1 356 TYR n 1 357 GLY n 1 358 LEU n 1 359 ALA n 1 360 LYS n 1 361 GLN n 1 362 PHE n 1 363 THR n 1 364 ILE n 1 365 LEU n 1 366 ASP n 1 367 SER n 1 368 LYS n 1 369 GLN n 1 370 PHE n 1 371 ILE n 1 372 LYS n 1 373 TYR n 1 374 TYR n 1 375 ASN n 1 376 TYR n 1 377 PHE n 1 378 PHE n 1 379 VAL n 1 380 SER n 1 381 TYR n 1 382 ASP n 1 383 SER n 1 384 SER n 1 385 VAL n 1 386 THR n 1 387 CYS n 1 388 ASP n 1 389 LYS n 1 390 THR n 1 391 CYS n 1 392 LYS n 1 393 ALA n 1 394 PHE n 1 395 GLN n 1 396 ILE n 1 397 CYS n 1 398 ALA n 1 399 ILE n 1 400 MET n 1 401 ASN n 1 402 LEU n 1 403 ASP n 1 404 ASN n 1 405 ILE n 1 406 SER n 1 407 TYR n 1 408 ALA n 1 409 ASP n 1 410 CYS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 410 _entity_src_gen.gene_src_common_name Human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'SMPDL3A, ASML3A' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'Fall armyworm' _entity_src_gen.pdbx_host_org_scientific_name 'Spodoptera frugiperda' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7108 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line Sf9 _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pFB-Sec-NH _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code ASM3A_HUMAN _struct_ref.pdbx_db_accession Q92484 _struct_ref.pdbx_db_isoform ? _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;PPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPP HVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFY SQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNE KLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQY YLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAIM NLDNISYADC ; _struct_ref.pdbx_align_begin 34 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5EBB A 1 ? 410 ? Q92484 34 ? 443 ? 34 443 2 1 5EBB B 1 ? 410 ? Q92484 34 ? 443 ? 34 443 3 1 5EBB C 1 ? 410 ? Q92484 34 ? 443 ? 34 443 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MLI non-polymer . 'MALONATE ION' ? 'C3 H2 O4 -2' 102.046 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5EBB _exptl.crystals_number ? _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 3.15 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 56.74 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH 7.2 _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 298 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '2.08 M disodium malonate pH 7.2, 0.23 M sodium thiocyanate and 0.01 M TCEP' _exptl_crystal_grow.pdbx_pH_range 7.2 # _diffrn.ambient_environment ? _diffrn.ambient_temp 80 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector PIXEL _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'DECTRIS PILATUS 2M' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2015-02-11 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9174 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'DIAMOND BEAMLINE I04-1' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.9174 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline I04-1 _diffrn_source.pdbx_synchrotron_site Diamond # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5EBB _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 2.6 _reflns.d_resolution_low 48.46 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all 61111 _reflns.number_obs 54349 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 99.5 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 5.7 _reflns.pdbx_Rmerge_I_obs 0.132 _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 9.8 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _reflns_shell.d_res_high 2.60 _reflns_shell.d_res_low 2.68 _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_obs 2.9 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_obs ? _reflns_shell.percent_possible_all 99.9 _reflns_shell.percent_possible_obs ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_obs 0.561 _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_gt ? _reflns_shell.number_unique_gt ? _reflns_shell.percent_possible_gt ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.pdbx_redundancy 5.9 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_CC_half ? _reflns_shell.pdbx_R_split ? # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 5EBB _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 51505 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 48.38 _refine.ls_d_res_high 2.60 _refine.ls_percent_reflns_obs 99.33 _refine.ls_R_factor_obs 0.23803 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.23712 _refine.ls_R_factor_R_free 0.25474 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.1 _refine.ls_number_reflns_R_free 2760 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.955 _refine.correlation_coeff_Fo_to_Fc_free 0.945 _refine.B_iso_mean 21.786 _refine.aniso_B[1][1] -0.15 _refine.aniso_B[2][2] -0.15 _refine.aniso_B[3][3] 0.48 _refine.aniso_B[1][2] -0.07 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct SAD _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.647 _refine.pdbx_overall_ESU_R_Free 0.304 _refine.overall_SU_ML 0.197 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 9.106 _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 9864 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 165 _refine_hist.number_atoms_solvent 301 _refine_hist.number_atoms_total 10330 _refine_hist.d_res_high 2.60 _refine_hist.d_res_low 48.38 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.022 0.020 ? 10405 'X-RAY DIFFRACTION' ? r_bond_other_d 0.002 0.020 ? 9571 'X-RAY DIFFRACTION' ? r_angle_refined_deg 2.124 1.960 ? 14212 'X-RAY DIFFRACTION' ? r_angle_other_deg 2.100 3.007 ? 22138 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 7.465 5.000 ? 1257 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 43.220 25.525 ? 476 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 18.035 15.000 ? 1664 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 18.141 15.000 ? 18 'X-RAY DIFFRACTION' ? r_chiral_restr 0.117 0.200 ? 1598 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.011 0.021 ? 11747 'X-RAY DIFFRACTION' ? r_gen_planes_other 0.009 0.020 ? 2367 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 1.865 2.043 ? 4968 'X-RAY DIFFRACTION' ? r_mcbond_other 1.865 2.043 ? 4967 'X-RAY DIFFRACTION' ? r_mcangle_it 3.025 3.060 ? 6221 'X-RAY DIFFRACTION' ? r_mcangle_other 3.024 3.060 ? 6222 'X-RAY DIFFRACTION' ? r_scbond_it 2.452 2.286 ? 5437 'X-RAY DIFFRACTION' ? r_scbond_other 2.452 2.287 ? 5438 'X-RAY DIFFRACTION' ? r_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_scangle_other 3.932 3.325 ? 7984 'X-RAY DIFFRACTION' ? r_long_range_B_refined 5.736 16.765 ? 12410 'X-RAY DIFFRACTION' ? r_long_range_B_other 5.736 16.768 ? 12411 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.600 _refine_ls_shell.d_res_low 2.667 _refine_ls_shell.number_reflns_R_work 3757 _refine_ls_shell.R_factor_R_work 0.292 _refine_ls_shell.percent_reflns_obs 99.82 _refine_ls_shell.R_factor_R_free 0.292 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 190 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? # _struct.entry_id 5EBB _struct.title 'Structure of human sphingomyelinase phosphodiesterase like 3A (SMPDL3A) with Zn2+' _struct.pdbx_descriptor 'Acid sphingomyelinase-like phosphodiesterase 3a (E.C.3.1.4.-)' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5EBB _struct_keywords.text 'calcineurin like phosphodiesterase, binuclear metallophosphodiesterase, acid sphingomyelinase like, hydrolase' _struct_keywords.pdbx_keywords HYDROLASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 1 ? D N N 2 ? E N N 2 ? F N N 3 ? G N N 3 ? H N N 3 ? I N N 4 ? J N N 2 ? K N N 2 ? L N N 3 ? M N N 3 ? N N N 3 ? O N N 4 ? P N N 5 ? Q N N 2 ? R N N 2 ? S N N 3 ? T N N 3 ? U N N 3 ? V N N 4 ? W N N 5 ? X N N 6 ? Y N N 6 ? Z N N 6 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 ASP A 24 ? VAL A 28 ? ASP A 57 VAL A 61 5 ? 5 HELX_P HELX_P2 AA2 CYS A 29 ? LYS A 33 ? CYS A 62 LYS A 66 5 ? 5 HELX_P HELX_P3 AA3 PRO A 51 ? SER A 65 ? PRO A 84 SER A 98 1 ? 15 HELX_P HELX_P4 AA4 PRO A 83 ? LEU A 87 ? PRO A 116 LEU A 120 5 ? 5 HELX_P HELX_P5 AA5 SER A 88 ? PHE A 107 ? SER A 121 PHE A 140 1 ? 20 HELX_P HELX_P6 AA6 SER A 132 ? LYS A 143 ? SER A 165 LYS A 176 1 ? 12 HELX_P HELX_P7 AA7 ASP A 147 ? GLY A 158 ? ASP A 180 GLY A 191 1 ? 12 HELX_P HELX_P8 AA8 ASN A 176 ? TYR A 181 ? ASN A 209 TYR A 214 5 ? 6 HELX_P HELX_P9 AA9 ASN A 184 ? LEU A 188 ? ASN A 217 LEU A 221 5 ? 5 HELX_P HELX_P10 AB1 ASP A 192 ? ALA A 194 ? ASP A 225 ALA A 227 5 ? 3 HELX_P HELX_P11 AB2 ASN A 195 ? ASN A 210 ? ASN A 228 ASN A 243 1 ? 16 HELX_P HELX_P12 AB3 ARG A 235 ? TYR A 249 ? ARG A 268 TYR A 282 1 ? 15 HELX_P HELX_P13 AB4 ASN A 323 ? GLY A 331 ? ASN A 356 GLY A 364 1 ? 9 HELX_P HELX_P14 AB5 LEU A 341 ? ASP A 346 ? LEU A 374 ASP A 379 1 ? 6 HELX_P HELX_P15 AB6 GLN A 351 ? THR A 363 ? GLN A 384 THR A 396 1 ? 13 HELX_P HELX_P16 AB7 SER A 367 ? PHE A 378 ? SER A 400 PHE A 411 1 ? 12 HELX_P HELX_P17 AB8 ASP A 388 ? ASN A 401 ? ASP A 421 ASN A 434 1 ? 14 HELX_P HELX_P18 AB9 ASP A 403 ? CYS A 410 ? ASP A 436 CYS A 443 1 ? 8 HELX_P HELX_P19 AC1 CYS B 29 ? LYS B 33 ? CYS B 62 LYS B 66 5 ? 5 HELX_P HELX_P20 AC2 PRO B 51 ? SER B 65 ? PRO B 84 SER B 98 1 ? 15 HELX_P HELX_P21 AC3 PRO B 83 ? LEU B 87 ? PRO B 116 LEU B 120 5 ? 5 HELX_P HELX_P22 AC4 SER B 88 ? PHE B 107 ? SER B 121 PHE B 140 1 ? 20 HELX_P HELX_P23 AC5 SER B 132 ? LYS B 143 ? SER B 165 LYS B 176 1 ? 12 HELX_P HELX_P24 AC6 ASP B 147 ? GLY B 158 ? ASP B 180 GLY B 191 1 ? 12 HELX_P HELX_P25 AC7 ASN B 176 ? TYR B 181 ? ASN B 209 TYR B 214 5 ? 6 HELX_P HELX_P26 AC8 ASN B 184 ? LEU B 188 ? ASN B 217 LEU B 221 5 ? 5 HELX_P HELX_P27 AC9 ASP B 192 ? ALA B 194 ? ASP B 225 ALA B 227 5 ? 3 HELX_P HELX_P28 AD1 ASN B 195 ? ASN B 210 ? ASN B 228 ASN B 243 1 ? 16 HELX_P HELX_P29 AD2 ARG B 235 ? TYR B 249 ? ARG B 268 TYR B 282 1 ? 15 HELX_P HELX_P30 AD3 ASN B 323 ? GLY B 331 ? ASN B 356 GLY B 364 1 ? 9 HELX_P HELX_P31 AD4 LEU B 341 ? TYR B 345 ? LEU B 374 TYR B 378 1 ? 5 HELX_P HELX_P32 AD5 GLN B 351 ? THR B 363 ? GLN B 384 THR B 396 1 ? 13 HELX_P HELX_P33 AD6 SER B 367 ? PHE B 378 ? SER B 400 PHE B 411 1 ? 12 HELX_P HELX_P34 AD7 ASP B 388 ? ASN B 401 ? ASP B 421 ASN B 434 1 ? 14 HELX_P HELX_P35 AD8 ASP B 403 ? CYS B 410 ? ASP B 436 CYS B 443 1 ? 8 HELX_P HELX_P36 AD9 ASP C 24 ? VAL C 28 ? ASP C 57 VAL C 61 5 ? 5 HELX_P HELX_P37 AE1 CYS C 29 ? LYS C 33 ? CYS C 62 LYS C 66 5 ? 5 HELX_P HELX_P38 AE2 PRO C 51 ? ASN C 64 ? PRO C 84 ASN C 97 1 ? 14 HELX_P HELX_P39 AE3 PRO C 83 ? LEU C 87 ? PRO C 116 LEU C 120 5 ? 5 HELX_P HELX_P40 AE4 SER C 88 ? PHE C 107 ? SER C 121 PHE C 140 1 ? 20 HELX_P HELX_P41 AE5 SER C 132 ? LYS C 143 ? SER C 165 LYS C 176 1 ? 12 HELX_P HELX_P42 AE6 ASP C 147 ? GLY C 158 ? ASP C 180 GLY C 191 1 ? 12 HELX_P HELX_P43 AE7 ASN C 176 ? TYR C 181 ? ASN C 209 TYR C 214 5 ? 6 HELX_P HELX_P44 AE8 ASN C 184 ? LEU C 188 ? ASN C 217 LEU C 221 5 ? 5 HELX_P HELX_P45 AE9 ASP C 192 ? ALA C 194 ? ASP C 225 ALA C 227 5 ? 3 HELX_P HELX_P46 AF1 ASN C 195 ? ASN C 210 ? ASN C 228 ASN C 243 1 ? 16 HELX_P HELX_P47 AF2 ARG C 235 ? TYR C 249 ? ARG C 268 TYR C 282 1 ? 15 HELX_P HELX_P48 AF3 ASN C 323 ? GLY C 331 ? ASN C 356 GLY C 364 1 ? 9 HELX_P HELX_P49 AF4 LEU C 341 ? ASP C 346 ? LEU C 374 ASP C 379 1 ? 6 HELX_P HELX_P50 AF5 GLN C 351 ? THR C 363 ? GLN C 384 THR C 396 1 ? 13 HELX_P HELX_P51 AF6 SER C 367 ? PHE C 378 ? SER C 400 PHE C 411 1 ? 12 HELX_P HELX_P52 AF7 ASP C 388 ? ASN C 401 ? ASP C 421 ASN C 434 1 ? 14 HELX_P HELX_P53 AF8 ASP C 403 ? CYS C 410 ? ASP C 436 CYS C 443 1 ? 8 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 29 SG ? ? ? 1_555 A CYS 48 SG ? ? A CYS 62 A CYS 81 1_555 ? ? ? ? ? ? ? 2.030 ? disulf2 disulf ? ? A CYS 397 SG ? ? ? 1_555 A CYS 410 SG ? ? A CYS 430 A CYS 443 1_555 ? ? ? ? ? ? ? 2.026 ? disulf3 disulf ? ? B CYS 29 SG ? ? ? 1_555 B CYS 48 SG ? ? B CYS 62 B CYS 81 1_555 ? ? ? ? ? ? ? 2.076 ? disulf4 disulf ? ? B CYS 397 SG ? ? ? 1_555 B CYS 410 SG ? ? B CYS 430 B CYS 443 1_555 ? ? ? ? ? ? ? 2.033 ? disulf5 disulf ? ? C CYS 29 SG ? ? ? 1_555 C CYS 48 SG ? ? C CYS 62 C CYS 81 1_555 ? ? ? ? ? ? ? 2.014 ? disulf6 disulf ? ? C CYS 397 SG ? ? ? 1_555 C CYS 410 SG ? ? C CYS 430 C CYS 443 1_555 ? ? ? ? ? ? ? 2.082 ? metalc1 metalc ? ? A ASP 12 OD2 ? ? ? 1_555 E ZN . ZN ? ? A ASP 45 A ZN 702 1_555 ? ? ? ? ? ? ? 2.033 ? metalc2 metalc ? ? A HIS 14 NE2 ? ? ? 1_555 E ZN . ZN ? ? A HIS 47 A ZN 702 1_555 ? ? ? ? ? ? ? 2.176 ? covale1 covale one ? A ASN 36 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 69 A NAG 703 1_555 ? ? ? ? ? ? ? 1.292 ? metalc3 metalc ? ? A ASP 77 OD2 ? ? ? 1_555 D ZN . ZN ? ? A ASP 110 A ZN 701 1_555 ? ? ? ? ? ? ? 2.266 ? metalc4 metalc ? ? A ASP 77 OD2 ? ? ? 1_555 E ZN . ZN ? ? A ASP 110 A ZN 702 1_555 ? ? ? ? ? ? ? 2.124 ? covale2 covale one ? A ASN 98 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 131 A NAG 704 1_555 ? ? ? ? ? ? ? 1.314 ? metalc5 metalc ? ? A ASN 118 OD1 ? ? ? 1_555 D ZN . ZN ? ? A ASN 151 A ZN 701 1_555 ? ? ? ? ? ? ? 2.076 ? metalc6 metalc ? ? A HIS 219 NE2 ? ? ? 1_555 D ZN . ZN ? ? A HIS 252 A ZN 701 1_555 ? ? ? ? ? ? ? 2.131 ? metalc7 metalc ? ? A HIS 260 ND1 ? ? ? 1_555 D ZN . ZN ? ? A HIS 293 A ZN 701 1_555 ? ? ? ? ? ? ? 2.258 ? metalc8 metalc ? ? A HIS 262 NE2 ? ? ? 1_555 E ZN . ZN ? ? A HIS 295 A ZN 702 1_555 ? ? ? ? ? ? ? 2.219 ? covale3 covale one ? A ASN 323 ND2 ? ? ? 1_555 H NAG . C1 ? ? A ASN 356 A NAG 705 1_555 ? ? ? ? ? ? ? 1.323 ? metalc9 metalc ? ? B ASP 12 OD2 ? ? ? 1_555 J ZN . ZN ? ? B ASP 45 B ZN 701 1_555 ? ? ? ? ? ? ? 2.363 ? metalc10 metalc ? ? B HIS 14 NE2 ? ? ? 1_555 J ZN . ZN ? ? B HIS 47 B ZN 701 1_555 ? ? ? ? ? ? ? 1.999 ? covale4 covale one ? B ASN 36 ND2 ? ? ? 1_555 L NAG . C1 ? ? B ASN 69 B NAG 703 1_555 ? ? ? ? ? ? ? 1.316 ? metalc11 metalc ? ? B ASP 77 OD2 ? ? ? 1_555 J ZN . ZN ? ? B ASP 110 B ZN 701 1_555 ? ? ? ? ? ? ? 2.274 ? metalc12 metalc ? ? B ASP 77 OD2 ? ? ? 1_555 K ZN . ZN ? ? B ASP 110 B ZN 702 1_555 ? ? ? ? ? ? ? 2.594 ? covale5 covale one ? B ASN 98 ND2 ? ? ? 1_555 M NAG . C1 ? ? B ASN 131 B NAG 704 1_555 ? ? ? ? ? ? ? 1.297 ? metalc13 metalc ? ? B ASN 118 OD1 ? ? ? 1_555 K ZN . ZN ? ? B ASN 151 B ZN 702 1_555 ? ? ? ? ? ? ? 2.040 ? metalc14 metalc ? ? B HIS 219 NE2 ? ? ? 1_555 K ZN . ZN ? ? B HIS 252 B ZN 702 1_555 ? ? ? ? ? ? ? 2.267 ? metalc15 metalc ? ? B HIS 260 ND1 ? ? ? 1_555 K ZN . ZN ? ? B HIS 293 B ZN 702 1_555 ? ? ? ? ? ? ? 2.437 ? metalc16 metalc ? ? B HIS 262 NE2 ? ? ? 1_555 J ZN . ZN ? ? B HIS 295 B ZN 701 1_555 ? ? ? ? ? ? ? 2.208 ? covale6 covale one ? B ASN 323 ND2 ? ? ? 1_555 N NAG . C1 ? ? B ASN 356 B NAG 705 1_555 ? ? ? ? ? ? ? 1.498 ? metalc17 metalc ? ? C ASP 12 OD1 ? ? ? 1_555 Q ZN . ZN ? ? C ASP 45 C ZN 701 1_555 ? ? ? ? ? ? ? 1.963 ? metalc18 metalc ? ? C HIS 14 NE2 ? ? ? 1_555 Q ZN . ZN ? ? C HIS 47 C ZN 701 1_555 ? ? ? ? ? ? ? 2.324 ? covale7 covale one ? C ASN 36 ND2 ? ? ? 1_555 S NAG . C1 ? ? C ASN 69 C NAG 703 1_555 ? ? ? ? ? ? ? 1.292 ? metalc19 metalc ? ? C ASP 77 OD2 ? ? ? 1_555 Q ZN . ZN ? ? C ASP 110 C ZN 701 1_555 ? ? ? ? ? ? ? 2.318 ? metalc20 metalc ? ? C ASP 77 OD2 ? ? ? 1_555 R ZN . ZN ? ? C ASP 110 C ZN 702 1_555 ? ? ? ? ? ? ? 2.438 ? covale8 covale one ? C ASN 98 ND2 ? ? ? 1_555 T NAG . C1 ? ? C ASN 131 C NAG 704 1_555 ? ? ? ? ? ? ? 1.589 ? metalc21 metalc ? ? C ASN 118 OD1 ? ? ? 1_555 R ZN . ZN ? ? C ASN 151 C ZN 702 1_555 ? ? ? ? ? ? ? 1.903 ? metalc22 metalc ? ? C HIS 219 NE2 ? ? ? 1_555 R ZN . ZN ? ? C HIS 252 C ZN 702 1_555 ? ? ? ? ? ? ? 2.061 ? metalc23 metalc ? ? C HIS 260 ND1 ? ? ? 1_555 R ZN . ZN ? ? C HIS 293 C ZN 702 1_555 ? ? ? ? ? ? ? 2.416 ? metalc24 metalc ? ? C HIS 262 NE2 ? ? ? 1_555 Q ZN . ZN ? ? C HIS 295 C ZN 701 1_555 ? ? ? ? ? ? ? 2.452 ? covale9 covale one ? C ASN 323 ND2 ? ? ? 1_555 U NAG . C1 ? ? C ASN 356 C NAG 705 1_555 ? ? ? ? ? ? ? 1.310 ? metalc25 metalc ? ? D ZN . ZN ? ? ? 1_555 I MLI . O7 ? ? A ZN 701 A MLI 706 1_555 ? ? ? ? ? ? ? 1.939 ? metalc26 metalc ? ? E ZN . ZN ? ? ? 1_555 I MLI . O6 ? ? A ZN 702 A MLI 706 1_555 ? ? ? ? ? ? ? 2.285 ? metalc27 metalc ? ? E ZN . ZN ? ? ? 1_555 I MLI . O7 ? ? A ZN 702 A MLI 706 1_555 ? ? ? ? ? ? ? 2.100 ? metalc28 metalc ? ? K ZN . ZN ? ? ? 1_555 O MLI . O9 ? ? B ZN 702 B MLI 706 1_555 ? ? ? ? ? ? ? 1.709 ? metalc29 metalc ? ? K ZN . ZN ? ? ? 1_555 O MLI . O8 ? ? B ZN 702 B MLI 706 1_555 ? ? ? ? ? ? ? 2.374 ? metalc30 metalc ? ? Q ZN . ZN ? ? ? 1_555 V MLI . O8 ? ? C ZN 701 C MLI 706 1_555 ? ? ? ? ? ? ? 2.363 ? metalc31 metalc ? ? Q ZN . ZN ? ? ? 1_555 V MLI . O9 ? ? C ZN 701 C MLI 706 1_555 ? ? ? ? ? ? ? 2.082 ? metalc32 metalc ? ? R ZN . ZN ? ? ? 1_555 V MLI . O9 ? ? C ZN 702 C MLI 706 1_555 ? ? ? ? ? ? ? 2.116 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 TRP 122 A . ? TRP 155 A PRO 123 A ? PRO 156 A 1 -1.85 2 TRP 122 B . ? TRP 155 B PRO 123 B ? PRO 156 B 1 -10.23 3 TRP 122 C . ? TRP 155 C PRO 123 C ? PRO 156 C 1 -8.01 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 6 ? AA2 ? 6 ? AA3 ? 6 ? AA4 ? 6 ? AA5 ? 6 ? AA6 ? 6 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? parallel AA1 2 3 ? parallel AA1 3 4 ? anti-parallel AA1 4 5 ? anti-parallel AA1 5 6 ? anti-parallel AA2 1 2 ? anti-parallel AA2 2 3 ? parallel AA2 3 4 ? parallel AA2 4 5 ? parallel AA2 5 6 ? anti-parallel AA3 1 2 ? parallel AA3 2 3 ? parallel AA3 3 4 ? anti-parallel AA3 4 5 ? anti-parallel AA3 5 6 ? anti-parallel AA4 1 2 ? anti-parallel AA4 2 3 ? parallel AA4 3 4 ? parallel AA4 4 5 ? parallel AA4 5 6 ? anti-parallel AA5 1 2 ? parallel AA5 2 3 ? parallel AA5 3 4 ? anti-parallel AA5 4 5 ? anti-parallel AA5 5 6 ? anti-parallel AA6 1 2 ? anti-parallel AA6 2 3 ? parallel AA6 3 4 ? parallel AA6 4 5 ? parallel AA6 5 6 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 VAL A 112 ? PRO A 114 ? VAL A 145 PRO A 147 AA1 2 PHE A 71 ? TRP A 74 ? PHE A 104 TRP A 107 AA1 3 GLY A 5 ? VAL A 10 ? GLY A 38 VAL A 43 AA1 4 GLY A 301 ? TYR A 307 ? GLY A 334 TYR A 340 AA1 5 LEU A 314 ? LEU A 322 ? LEU A 347 LEU A 355 AA1 6 TRP A 335 ? ILE A 340 ? TRP A 368 ILE A 373 AA2 1 TYR A 160 ? VAL A 164 ? TYR A 193 VAL A 197 AA2 2 ASN A 167 ? SER A 174 ? ASN A 200 SER A 207 AA2 3 LYS A 213 ? ILE A 217 ? LYS A 246 ILE A 250 AA2 4 ILE A 253 ? TYR A 258 ? ILE A 286 TYR A 291 AA2 5 PRO A 276 ? VAL A 282 ? PRO A 309 VAL A 315 AA2 6 SER A 265 ? SER A 270 ? SER A 298 SER A 303 AA3 1 GLN B 111 ? PRO B 114 ? GLN B 144 PRO B 147 AA3 2 PHE B 71 ? TRP B 74 ? PHE B 104 TRP B 107 AA3 3 GLY B 5 ? VAL B 10 ? GLY B 38 VAL B 43 AA3 4 GLY B 301 ? TYR B 307 ? GLY B 334 TYR B 340 AA3 5 LEU B 314 ? LEU B 322 ? LEU B 347 LEU B 355 AA3 6 TRP B 335 ? ILE B 340 ? TRP B 368 ILE B 373 AA4 1 TYR B 160 ? VAL B 164 ? TYR B 193 VAL B 197 AA4 2 ASN B 167 ? SER B 174 ? ASN B 200 SER B 207 AA4 3 LYS B 213 ? ILE B 217 ? LYS B 246 ILE B 250 AA4 4 ILE B 253 ? TYR B 258 ? ILE B 286 TYR B 291 AA4 5 PRO B 276 ? VAL B 282 ? PRO B 309 VAL B 315 AA4 6 SER B 265 ? SER B 270 ? SER B 298 SER B 303 AA5 1 VAL C 112 ? PRO C 114 ? VAL C 145 PRO C 147 AA5 2 PHE C 71 ? TRP C 74 ? PHE C 104 TRP C 107 AA5 3 GLY C 5 ? VAL C 10 ? GLY C 38 VAL C 43 AA5 4 GLY C 301 ? TYR C 307 ? GLY C 334 TYR C 340 AA5 5 LEU C 314 ? LEU C 322 ? LEU C 347 LEU C 355 AA5 6 TRP C 335 ? ILE C 340 ? TRP C 368 ILE C 373 AA6 1 TYR C 160 ? VAL C 164 ? TYR C 193 VAL C 197 AA6 2 ASN C 167 ? LEU C 175 ? ASN C 200 LEU C 208 AA6 3 LYS C 213 ? ALA C 218 ? LYS C 246 ALA C 251 AA6 4 ILE C 253 ? TYR C 258 ? ILE C 286 TYR C 291 AA6 5 PRO C 276 ? VAL C 282 ? PRO C 309 VAL C 315 AA6 6 SER C 265 ? SER C 270 ? SER C 298 SER C 303 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 O PHE A 113 ? O PHE A 146 N MET A 72 ? N MET A 105 AA1 2 3 O ILE A 73 ? O ILE A 106 N TRP A 8 ? N TRP A 41 AA1 3 4 N HIS A 9 ? N HIS A 42 O ARG A 303 ? O ARG A 336 AA1 4 5 N LEU A 304 ? N LEU A 337 O LEU A 318 ? O LEU A 351 AA1 5 6 N TYR A 321 ? N TYR A 354 O LYS A 336 ? O LYS A 369 AA2 1 2 N TYR A 160 ? N TYR A 193 O SER A 174 ? O SER A 207 AA2 2 3 N ARG A 171 ? N ARG A 204 O LYS A 213 ? O LYS A 246 AA2 3 4 N VAL A 214 ? N VAL A 247 O ALA A 254 ? O ALA A 287 AA2 4 5 N GLN A 256 ? N GLN A 289 O PHE A 281 ? O PHE A 314 AA2 5 6 O VAL A 277 ? O VAL A 310 N LEU A 269 ? N LEU A 302 AA3 1 2 O PHE B 113 ? O PHE B 146 N MET B 72 ? N MET B 105 AA3 2 3 O ILE B 73 ? O ILE B 106 N VAL B 10 ? N VAL B 43 AA3 3 4 N HIS B 9 ? N HIS B 42 O ARG B 303 ? O ARG B 336 AA3 4 5 N ILE B 302 ? N ILE B 335 O TYR B 320 ? O TYR B 353 AA3 5 6 N TYR B 321 ? N TYR B 354 O LYS B 336 ? O LYS B 369 AA4 1 2 N TYR B 160 ? N TYR B 193 O SER B 174 ? O SER B 207 AA4 2 3 N ARG B 171 ? N ARG B 204 O LYS B 213 ? O LYS B 246 AA4 3 4 N ILE B 216 ? N ILE B 249 O GLY B 255 ? O GLY B 288 AA4 4 5 N TYR B 258 ? N TYR B 291 O PHE B 281 ? O PHE B 314 AA4 5 6 O VAL B 277 ? O VAL B 310 N LEU B 269 ? N LEU B 302 AA5 1 2 O PHE C 113 ? O PHE C 146 N MET C 72 ? N MET C 105 AA5 2 3 O ILE C 73 ? O ILE C 106 N TRP C 8 ? N TRP C 41 AA5 3 4 N PHE C 7 ? N PHE C 40 O PHE C 305 ? O PHE C 338 AA5 4 5 N ILE C 302 ? N ILE C 335 O TYR C 320 ? O TYR C 353 AA5 5 6 N TYR C 321 ? N TYR C 354 O LYS C 336 ? O LYS C 369 AA6 1 2 N TYR C 160 ? N TYR C 193 O SER C 174 ? O SER C 207 AA6 2 3 N ARG C 171 ? N ARG C 204 O LYS C 213 ? O LYS C 246 AA6 3 4 N VAL C 214 ? N VAL C 247 O ALA C 254 ? O ALA C 287 AA6 4 5 N TYR C 258 ? N TYR C 291 O PHE C 281 ? O PHE C 314 AA6 5 6 O VAL C 282 ? O VAL C 315 N SER C 265 ? N SER C 298 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A ZN 701 ? 6 'binding site for residue ZN A 701' AC2 Software A ZN 702 ? 6 'binding site for residue ZN A 702' AC3 Software A MLI 706 ? 12 'binding site for residue MLI A 706' AC4 Software B ZN 701 ? 6 'binding site for residue ZN B 701' AC5 Software B ZN 702 ? 6 'binding site for residue ZN B 702' AC6 Software B MLI 706 ? 10 'binding site for residue MLI B 706' AC7 Software B GOL 707 ? 5 'binding site for residue GOL B 707' AC8 Software C ZN 701 ? 6 'binding site for residue ZN C 701' AC9 Software C ZN 702 ? 7 'binding site for residue ZN C 702' AD1 Software C MLI 706 ? 10 'binding site for residue MLI C 706' AD2 Software C GOL 707 ? 3 'binding site for residue GOL C 707' AD3 Software A NAG 703 ? 3 'binding site for Mono-Saccharide NAG A 703 bound to ASN A 69' AD4 Software A NAG 704 ? 3 'binding site for Mono-Saccharide NAG A 704 bound to ASN A 131' AD5 Software A NAG 705 ? 3 'binding site for Mono-Saccharide NAG A 705 bound to ASN A 356' AD6 Software B NAG 703 ? 4 'binding site for Mono-Saccharide NAG B 703 bound to ASN B 69' AD7 Software B NAG 704 ? 4 'binding site for Mono-Saccharide NAG B 704 bound to ASN B 131' AD8 Software B NAG 705 ? 5 'binding site for Mono-Saccharide NAG B 705 bound to ASN B 356' AD9 Software C NAG 703 ? 5 'binding site for Mono-Saccharide NAG C 703 bound to ASN C 69' AE1 Software C NAG 704 ? 5 'binding site for Mono-Saccharide NAG C 704 bound to ASN C 131' AE2 Software C NAG 705 ? 3 'binding site for Mono-Saccharide NAG C 705 bound to ASN C 356' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 6 ASP A 77 ? ASP A 110 . ? 1_555 ? 2 AC1 6 ASN A 118 ? ASN A 151 . ? 1_555 ? 3 AC1 6 HIS A 219 ? HIS A 252 . ? 1_555 ? 4 AC1 6 HIS A 260 ? HIS A 293 . ? 1_555 ? 5 AC1 6 ZN E . ? ZN A 702 . ? 1_555 ? 6 AC1 6 MLI I . ? MLI A 706 . ? 1_555 ? 7 AC2 6 ASP A 12 ? ASP A 45 . ? 1_555 ? 8 AC2 6 HIS A 14 ? HIS A 47 . ? 1_555 ? 9 AC2 6 ASP A 77 ? ASP A 110 . ? 1_555 ? 10 AC2 6 HIS A 262 ? HIS A 295 . ? 1_555 ? 11 AC2 6 ZN D . ? ZN A 701 . ? 1_555 ? 12 AC2 6 MLI I . ? MLI A 706 . ? 1_555 ? 13 AC3 12 ASP A 12 ? ASP A 45 . ? 1_555 ? 14 AC3 12 HIS A 14 ? HIS A 47 . ? 1_555 ? 15 AC3 12 ASP A 77 ? ASP A 110 . ? 1_555 ? 16 AC3 12 HIS A 81 ? HIS A 114 . ? 1_555 ? 17 AC3 12 ASN A 118 ? ASN A 151 . ? 1_555 ? 18 AC3 12 HIS A 119 ? HIS A 152 . ? 1_555 ? 19 AC3 12 TYR A 181 ? TYR A 214 . ? 1_555 ? 20 AC3 12 HIS A 219 ? HIS A 252 . ? 1_555 ? 21 AC3 12 HIS A 260 ? HIS A 293 . ? 1_555 ? 22 AC3 12 HIS A 262 ? HIS A 295 . ? 1_555 ? 23 AC3 12 ZN D . ? ZN A 701 . ? 1_555 ? 24 AC3 12 ZN E . ? ZN A 702 . ? 1_555 ? 25 AC4 6 ASP B 12 ? ASP B 45 . ? 1_555 ? 26 AC4 6 HIS B 14 ? HIS B 47 . ? 1_555 ? 27 AC4 6 ASP B 77 ? ASP B 110 . ? 1_555 ? 28 AC4 6 HIS B 262 ? HIS B 295 . ? 1_555 ? 29 AC4 6 ZN K . ? ZN B 702 . ? 1_555 ? 30 AC4 6 MLI O . ? MLI B 706 . ? 1_555 ? 31 AC5 6 ASP B 77 ? ASP B 110 . ? 1_555 ? 32 AC5 6 ASN B 118 ? ASN B 151 . ? 1_555 ? 33 AC5 6 HIS B 219 ? HIS B 252 . ? 1_555 ? 34 AC5 6 HIS B 260 ? HIS B 293 . ? 1_555 ? 35 AC5 6 ZN J . ? ZN B 701 . ? 1_555 ? 36 AC5 6 MLI O . ? MLI B 706 . ? 1_555 ? 37 AC6 10 ASP B 12 ? ASP B 45 . ? 1_555 ? 38 AC6 10 HIS B 14 ? HIS B 47 . ? 1_555 ? 39 AC6 10 ASP B 77 ? ASP B 110 . ? 1_555 ? 40 AC6 10 HIS B 81 ? HIS B 114 . ? 1_555 ? 41 AC6 10 ASN B 118 ? ASN B 151 . ? 1_555 ? 42 AC6 10 HIS B 119 ? HIS B 152 . ? 1_555 ? 43 AC6 10 HIS B 260 ? HIS B 293 . ? 1_555 ? 44 AC6 10 HIS B 262 ? HIS B 295 . ? 1_555 ? 45 AC6 10 ZN J . ? ZN B 701 . ? 1_555 ? 46 AC6 10 ZN K . ? ZN B 702 . ? 1_555 ? 47 AC7 5 GLN B 67 ? GLN B 100 . ? 1_555 ? 48 AC7 5 HOH Y . ? HOH B 826 . ? 1_555 ? 49 AC7 5 HOH Y . ? HOH B 861 . ? 1_555 ? 50 AC7 5 HOH Y . ? HOH B 875 . ? 1_555 ? 51 AC7 5 ALA C 3 ? ALA C 36 . ? 1_555 ? 52 AC8 6 ASP C 12 ? ASP C 45 . ? 1_555 ? 53 AC8 6 HIS C 14 ? HIS C 47 . ? 1_555 ? 54 AC8 6 ASP C 77 ? ASP C 110 . ? 1_555 ? 55 AC8 6 HIS C 262 ? HIS C 295 . ? 1_555 ? 56 AC8 6 ZN R . ? ZN C 702 . ? 1_555 ? 57 AC8 6 MLI V . ? MLI C 706 . ? 1_555 ? 58 AC9 7 ASP C 12 ? ASP C 45 . ? 1_555 ? 59 AC9 7 ASP C 77 ? ASP C 110 . ? 1_555 ? 60 AC9 7 ASN C 118 ? ASN C 151 . ? 1_555 ? 61 AC9 7 HIS C 219 ? HIS C 252 . ? 1_555 ? 62 AC9 7 HIS C 260 ? HIS C 293 . ? 1_555 ? 63 AC9 7 ZN Q . ? ZN C 701 . ? 1_555 ? 64 AC9 7 MLI V . ? MLI C 706 . ? 1_555 ? 65 AD1 10 ASP C 12 ? ASP C 45 . ? 1_555 ? 66 AD1 10 HIS C 14 ? HIS C 47 . ? 1_555 ? 67 AD1 10 ASP C 77 ? ASP C 110 . ? 1_555 ? 68 AD1 10 HIS C 81 ? HIS C 114 . ? 1_555 ? 69 AD1 10 ASN C 118 ? ASN C 151 . ? 1_555 ? 70 AD1 10 HIS C 119 ? HIS C 152 . ? 1_555 ? 71 AD1 10 HIS C 260 ? HIS C 293 . ? 1_555 ? 72 AD1 10 HIS C 262 ? HIS C 295 . ? 1_555 ? 73 AD1 10 ZN Q . ? ZN C 701 . ? 1_555 ? 74 AD1 10 ZN R . ? ZN C 702 . ? 1_555 ? 75 AD2 3 PRO C 17 ? PRO C 50 . ? 1_555 ? 76 AD2 3 NAG T . ? NAG C 704 . ? 1_555 ? 77 AD2 3 HOH Z . ? HOH C 833 . ? 1_555 ? 78 AD3 3 ASN A 36 ? ASN A 69 . ? 1_555 ? 79 AD3 3 ILE A 371 ? ILE A 404 . ? 5_555 ? 80 AD3 3 THR A 386 ? THR A 419 . ? 5_555 ? 81 AD4 3 TYR A 52 ? TYR A 85 . ? 1_555 ? 82 AD4 3 ASN A 98 ? ASN A 131 . ? 1_555 ? 83 AD4 3 THR A 101 ? THR A 134 . ? 1_555 ? 84 AD5 3 ASN A 323 ? ASN A 356 . ? 1_555 ? 85 AD5 3 SER A 380 ? SER A 413 . ? 1_555 ? 86 AD5 3 LYS B 211 ? LYS B 244 . ? 1_555 ? 87 AD6 4 GLY B 34 ? GLY B 67 . ? 1_555 ? 88 AD6 4 ASN B 36 ? ASN B 69 . ? 1_555 ? 89 AD6 4 LYS C 368 ? LYS C 401 . ? 5_565 ? 90 AD6 4 THR C 386 ? THR C 419 . ? 5_565 ? 91 AD7 4 PRO B 17 ? PRO B 50 . ? 1_555 ? 92 AD7 4 TYR B 52 ? TYR B 85 . ? 1_555 ? 93 AD7 4 ASN B 98 ? ASN B 131 . ? 1_555 ? 94 AD7 4 THR B 102 ? THR B 135 . ? 1_555 ? 95 AD8 5 TYR B 321 ? TYR B 354 . ? 1_555 ? 96 AD8 5 ASN B 323 ? ASN B 356 . ? 1_555 ? 97 AD8 5 GLU B 326 ? GLU B 359 . ? 1_555 ? 98 AD8 5 SER B 380 ? SER B 413 . ? 1_555 ? 99 AD8 5 HOH Y . ? HOH B 854 . ? 1_555 ? 100 AD9 5 ILE B 371 ? ILE B 404 . ? 5_665 ? 101 AD9 5 THR B 386 ? THR B 419 . ? 5_665 ? 102 AD9 5 THR C 26 ? THR C 59 . ? 1_555 ? 103 AD9 5 GLY C 34 ? GLY C 67 . ? 1_555 ? 104 AD9 5 ASN C 36 ? ASN C 69 . ? 1_555 ? 105 AE1 5 PRO C 17 ? PRO C 50 . ? 1_555 ? 106 AE1 5 TYR C 52 ? TYR C 85 . ? 1_555 ? 107 AE1 5 ASN C 98 ? ASN C 131 . ? 1_555 ? 108 AE1 5 GOL W . ? GOL C 707 . ? 1_555 ? 109 AE1 5 HOH Z . ? HOH C 806 . ? 1_555 ? 110 AE2 3 LYS A 211 ? LYS A 244 . ? 1_555 ? 111 AE2 3 ASN C 323 ? ASN C 356 . ? 1_555 ? 112 AE2 3 SER C 380 ? SER C 413 . ? 1_555 ? # _atom_sites.entry_id 5EBB _atom_sites.fract_transf_matrix[1][1] 0.006766 _atom_sites.fract_transf_matrix[1][2] 0.003907 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.007813 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007148 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . PRO A 1 1 ? -14.854 44.311 31.870 1.00 33.16 ? 34 PRO A N 1 ATOM 2 C CA . PRO A 1 1 ? -14.346 44.880 30.611 1.00 33.04 ? 34 PRO A CA 1 ATOM 3 C C . PRO A 1 1 ? -15.458 45.417 29.718 1.00 28.28 ? 34 PRO A C 1 ATOM 4 O O . PRO A 1 1 ? -16.436 44.740 29.528 1.00 30.49 ? 34 PRO A O 1 ATOM 5 C CB . PRO A 1 1 ? -13.702 43.662 29.916 1.00 32.89 ? 34 PRO A CB 1 ATOM 6 C CG . PRO A 1 1 ? -14.439 42.490 30.456 1.00 32.01 ? 34 PRO A CG 1 ATOM 7 C CD . PRO A 1 1 ? -15.269 42.924 31.660 1.00 33.73 ? 34 PRO A CD 1 ATOM 8 N N . PRO A 1 2 ? -15.272 46.582 29.117 1.00 26.13 ? 35 PRO A N 1 ATOM 9 C CA . PRO A 1 2 ? -16.286 47.264 28.316 1.00 26.25 ? 35 PRO A CA 1 ATOM 10 C C . PRO A 1 2 ? -16.692 46.588 27.000 1.00 23.00 ? 35 PRO A C 1 ATOM 11 O O . PRO A 1 2 ? -17.758 46.869 26.519 1.00 22.85 ? 35 PRO A O 1 ATOM 12 C CB . PRO A 1 2 ? -15.613 48.591 28.011 1.00 28.18 ? 35 PRO A CB 1 ATOM 13 C CG . PRO A 1 2 ? -14.189 48.197 27.868 1.00 28.02 ? 35 PRO A CG 1 ATOM 14 C CD . PRO A 1 2 ? -13.967 47.234 28.977 1.00 27.52 ? 35 PRO A CD 1 ATOM 15 N N . ALA A 1 3 ? -15.845 45.740 26.429 1.00 20.46 ? 36 ALA A N 1 ATOM 16 C CA . ALA A 1 3 ? -16.233 44.834 25.352 1.00 19.18 ? 36 ALA A CA 1 ATOM 17 C C . ALA A 1 3 ? -15.553 43.483 25.515 1.00 18.93 ? 36 ALA A C 1 ATOM 18 O O . ALA A 1 3 ? -14.547 43.351 26.191 1.00 18.52 ? 36 ALA A O 1 ATOM 19 C CB . ALA A 1 3 ? -15.893 45.409 24.002 1.00 18.68 ? 36 ALA A CB 1 ATOM 20 N N . ILE A 1 4 ? -16.131 42.480 24.877 1.00 18.55 ? 37 ILE A N 1 ATOM 21 C CA . ILE A 1 4 ? -15.678 41.100 24.970 1.00 17.33 ? 37 ILE A CA 1 ATOM 22 C C . ILE A 1 4 ? -15.262 40.707 23.571 1.00 14.31 ? 37 ILE A C 1 ATOM 23 O O . ILE A 1 4 ? -16.031 40.866 22.645 1.00 13.37 ? 37 ILE A O 1 ATOM 24 C CB . ILE A 1 4 ? -16.825 40.166 25.359 1.00 18.92 ? 37 ILE A CB 1 ATOM 25 C CG1 . ILE A 1 4 ? -17.445 40.567 26.705 1.00 21.33 ? 37 ILE A CG1 1 ATOM 26 C CG2 . ILE A 1 4 ? -16.327 38.742 25.498 1.00 20.19 ? 37 ILE A CG2 1 ATOM 27 C CD1 . ILE A 1 4 ? -16.653 40.150 27.947 1.00 21.17 ? 37 ILE A CD1 1 ATOM 28 N N . GLY A 1 5 ? -14.052 40.198 23.428 1.00 12.13 ? 38 GLY A N 1 ATOM 29 C CA . GLY A 1 5 ? -13.612 39.607 22.169 1.00 11.27 ? 38 GLY A CA 1 ATOM 30 C C . GLY A 1 5 ? -13.994 38.132 22.149 1.00 10.23 ? 38 GLY A C 1 ATOM 31 O O . GLY A 1 5 ? -14.141 37.520 23.207 1.00 9.72 ? 38 GLY A O 1 ATOM 32 N N . GLN A 1 6 ? -14.192 37.595 20.944 1.00 9.20 ? 39 GLN A N 1 ATOM 33 C CA . GLN A 1 6 ? -14.467 36.181 20.731 1.00 8.58 ? 39 GLN A CA 1 ATOM 34 C C . GLN A 1 6 ? -13.760 35.614 19.532 1.00 8.42 ? 39 GLN A C 1 ATOM 35 O O . GLN A 1 6 ? -13.655 36.266 18.500 1.00 9.69 ? 39 GLN A O 1 ATOM 36 C CB . GLN A 1 6 ? -15.946 35.965 20.558 1.00 8.14 ? 39 GLN A CB 1 ATOM 37 C CG . GLN A 1 6 ? -16.751 36.528 21.719 1.00 8.04 ? 39 GLN A CG 1 ATOM 38 C CD . GLN A 1 6 ? -18.168 36.032 21.787 1.00 7.85 ? 39 GLN A CD 1 ATOM 39 O OE1 . GLN A 1 6 ? -18.857 35.893 20.796 1.00 8.02 ? 39 GLN A OE1 1 ATOM 40 N NE2 . GLN A 1 6 ? -18.615 35.801 22.962 1.00 8.16 ? 39 GLN A NE2 1 ATOM 41 N N . PHE A 1 7 ? -13.282 34.395 19.645 1.00 7.86 ? 40 PHE A N 1 ATOM 42 C CA . PHE A 1 7 ? -12.815 33.655 18.480 1.00 7.44 ? 40 PHE A CA 1 ATOM 43 C C . PHE A 1 7 ? -13.224 32.197 18.523 1.00 7.10 ? 40 PHE A C 1 ATOM 44 O O . PHE A 1 7 ? -13.338 31.585 19.583 1.00 7.11 ? 40 PHE A O 1 ATOM 45 C CB . PHE A 1 7 ? -11.300 33.770 18.337 1.00 7.59 ? 40 PHE A CB 1 ATOM 46 C CG . PHE A 1 7 ? -10.499 33.169 19.454 1.00 7.43 ? 40 PHE A CG 1 ATOM 47 C CD1 . PHE A 1 7 ? -10.228 33.878 20.566 1.00 7.65 ? 40 PHE A CD1 1 ATOM 48 C CD2 . PHE A 1 7 ? -9.945 31.927 19.328 1.00 7.68 ? 40 PHE A CD2 1 ATOM 49 C CE1 . PHE A 1 7 ? -9.421 33.361 21.587 1.00 7.79 ? 40 PHE A CE1 1 ATOM 50 C CE2 . PHE A 1 7 ? -9.139 31.388 20.302 1.00 7.72 ? 40 PHE A CE2 1 ATOM 51 C CZ . PHE A 1 7 ? -8.878 32.114 21.456 1.00 7.83 ? 40 PHE A CZ 1 ATOM 52 N N . TRP A 1 8 ? -13.446 31.644 17.358 1.00 6.82 ? 41 TRP A N 1 ATOM 53 C CA . TRP A 1 8 ? -13.858 30.251 17.242 1.00 6.76 ? 41 TRP A CA 1 ATOM 54 C C . TRP A 1 8 ? -12.610 29.392 17.189 1.00 6.59 ? 41 TRP A C 1 ATOM 55 O O . TRP A 1 8 ? -11.532 29.846 16.752 1.00 6.84 ? 41 TRP A O 1 ATOM 56 C CB . TRP A 1 8 ? -14.674 30.050 15.966 1.00 6.75 ? 41 TRP A CB 1 ATOM 57 C CG . TRP A 1 8 ? -16.040 30.656 15.978 1.00 6.92 ? 41 TRP A CG 1 ATOM 58 C CD1 . TRP A 1 8 ? -16.436 31.822 15.381 1.00 7.15 ? 41 TRP A CD1 1 ATOM 59 C CD2 . TRP A 1 8 ? -17.205 30.116 16.597 1.00 6.98 ? 41 TRP A CD2 1 ATOM 60 N NE1 . TRP A 1 8 ? -17.790 32.037 15.601 1.00 7.13 ? 41 TRP A NE1 1 ATOM 61 C CE2 . TRP A 1 8 ? -18.273 30.975 16.314 1.00 6.95 ? 41 TRP A CE2 1 ATOM 62 C CE3 . TRP A 1 8 ? -17.451 28.968 17.325 1.00 7.18 ? 41 TRP A CE3 1 ATOM 63 C CZ2 . TRP A 1 8 ? -19.512 30.739 16.744 1.00 6.99 ? 41 TRP A CZ2 1 ATOM 64 C CZ3 . TRP A 1 8 ? -18.688 28.751 17.762 1.00 7.29 ? 41 TRP A CZ3 1 ATOM 65 C CH2 . TRP A 1 8 ? -19.707 29.638 17.482 1.00 7.18 ? 41 TRP A CH2 1 ATOM 66 N N . HIS A 1 9 ? -12.732 28.159 17.639 1.00 6.35 ? 42 HIS A N 1 ATOM 67 C CA . HIS A 1 9 ? -11.644 27.172 17.442 1.00 6.04 ? 42 HIS A CA 1 ATOM 68 C C . HIS A 1 9 ? -12.264 25.926 16.886 1.00 5.59 ? 42 HIS A C 1 ATOM 69 O O . HIS A 1 9 ? -13.103 25.341 17.538 1.00 5.53 ? 42 HIS A O 1 ATOM 70 C CB . HIS A 1 9 ? -10.975 26.860 18.754 1.00 6.23 ? 42 HIS A CB 1 ATOM 71 C CG . HIS A 1 9 ? -9.829 25.910 18.658 1.00 6.58 ? 42 HIS A CG 1 ATOM 72 N ND1 . HIS A 1 9 ? -9.123 25.497 19.766 1.00 6.72 ? 42 HIS A ND1 1 ATOM 73 C CD2 . HIS A 1 9 ? -9.278 25.273 17.599 1.00 6.73 ? 42 HIS A CD2 1 ATOM 74 C CE1 . HIS A 1 9 ? -8.182 24.654 19.390 1.00 6.91 ? 42 HIS A CE1 1 ATOM 75 N NE2 . HIS A 1 9 ? -8.236 24.527 18.074 1.00 6.86 ? 42 HIS A NE2 1 ATOM 76 N N . VAL A 1 10 ? -11.891 25.574 15.660 1.00 5.18 ? 43 VAL A N 1 ATOM 77 C CA . VAL A 1 10 ? -12.298 24.334 15.040 1.00 5.05 ? 43 VAL A CA 1 ATOM 78 C C . VAL A 1 10 ? -11.087 23.516 14.674 1.00 4.69 ? 43 VAL A C 1 ATOM 79 O O . VAL A 1 10 ? -10.089 24.079 14.322 1.00 4.64 ? 43 VAL A O 1 ATOM 80 C CB . VAL A 1 10 ? -13.089 24.556 13.731 1.00 5.29 ? 43 VAL A CB 1 ATOM 81 C CG1 . VAL A 1 10 ? -14.376 25.313 14.020 1.00 5.41 ? 43 VAL A CG1 1 ATOM 82 C CG2 . VAL A 1 10 ? -12.240 25.269 12.721 1.00 5.36 ? 43 VAL A CG2 1 ATOM 83 N N . THR A 1 11 ? -11.200 22.190 14.771 1.00 4.40 ? 44 THR A N 1 ATOM 84 C CA . THR A 1 11 ? -10.065 21.316 14.571 1.00 4.28 ? 44 THR A CA 1 ATOM 85 C C . THR A 1 11 ? -10.488 19.921 14.126 1.00 4.37 ? 44 THR A C 1 ATOM 86 O O . THR A 1 11 ? -11.595 19.480 14.402 1.00 4.40 ? 44 THR A O 1 ATOM 87 C CB . THR A 1 11 ? -9.229 21.209 15.826 1.00 4.12 ? 44 THR A CB 1 ATOM 88 O OG1 . THR A 1 11 ? -7.961 20.631 15.534 1.00 3.99 ? 44 THR A OG1 1 ATOM 89 C CG2 . THR A 1 11 ? -9.943 20.405 16.848 1.00 4.09 ? 44 THR A CG2 1 ATOM 90 N N . ASP A 1 12 ? -9.597 19.274 13.383 1.00 4.30 ? 45 ASP A N 1 ATOM 91 C CA . ASP A 1 12 ? -9.735 17.900 13.067 1.00 4.45 ? 45 ASP A CA 1 ATOM 92 C C . ASP A 1 12 ? -11.044 17.593 12.339 1.00 4.40 ? 45 ASP A C 1 ATOM 93 O O . ASP A 1 12 ? -11.805 16.727 12.745 1.00 4.26 ? 45 ASP A O 1 ATOM 94 C CB . ASP A 1 12 ? -9.554 17.042 14.335 1.00 4.60 ? 45 ASP A CB 1 ATOM 95 C CG . ASP A 1 12 ? -8.158 17.130 14.901 1.00 4.58 ? 45 ASP A CG 1 ATOM 96 O OD1 . ASP A 1 12 ? -7.915 17.998 15.708 1.00 4.54 ? 45 ASP A OD1 1 ATOM 97 O OD2 . ASP A 1 12 ? -7.278 16.371 14.486 1.00 4.99 -1 45 ASP A OD2 1 ATOM 98 N N . LEU A 1 13 ? -11.230 18.273 11.198 1.00 4.51 ? 46 LEU A N 1 ATOM 99 C CA . LEU A 1 13 ? -12.412 18.141 10.380 1.00 4.49 ? 46 LEU A CA 1 ATOM 100 C C . LEU A 1 13 ? -12.451 16.769 9.719 1.00 4.50 ? 46 LEU A C 1 ATOM 101 O O . LEU A 1 13 ? -13.500 16.173 9.620 1.00 4.47 ? 46 LEU A O 1 ATOM 102 C CB . LEU A 1 13 ? -12.461 19.255 9.310 1.00 4.51 ? 46 LEU A CB 1 ATOM 103 C CG . LEU A 1 13 ? -12.470 20.716 9.759 1.00 4.59 ? 46 LEU A CG 1 ATOM 104 C CD1 . LEU A 1 13 ? -12.614 21.742 8.646 1.00 4.62 ? 46 LEU A CD1 1 ATOM 105 C CD2 . LEU A 1 13 ? -13.602 20.975 10.691 1.00 4.69 ? 46 LEU A CD2 1 ATOM 106 N N . HIS A 1 14 ? -11.300 16.290 9.261 1.00 4.65 ? 47 HIS A N 1 ATOM 107 C CA . HIS A 1 14 ? -11.149 14.981 8.626 1.00 4.80 ? 47 HIS A CA 1 ATOM 108 C C . HIS A 1 14 ? -12.289 14.638 7.677 1.00 5.09 ? 47 HIS A C 1 ATOM 109 O O . HIS A 1 14 ? -13.060 13.686 7.901 1.00 4.94 ? 47 HIS A O 1 ATOM 110 C CB . HIS A 1 14 ? -11.046 13.905 9.674 1.00 4.88 ? 47 HIS A CB 1 ATOM 111 C CG . HIS A 1 14 ? -9.804 13.938 10.477 1.00 4.97 ? 47 HIS A CG 1 ATOM 112 N ND1 . HIS A 1 14 ? -8.579 13.630 9.947 1.00 4.87 ? 47 HIS A ND1 1 ATOM 113 C CD2 . HIS A 1 14 ? -9.599 14.163 11.802 1.00 5.29 ? 47 HIS A CD2 1 ATOM 114 C CE1 . HIS A 1 14 ? -7.670 13.650 10.908 1.00 5.13 ? 47 HIS A CE1 1 ATOM 115 N NE2 . HIS A 1 14 ? -8.255 13.993 12.044 1.00 5.13 ? 47 HIS A NE2 1 ATOM 116 N N . LEU A 1 15 ? -12.399 15.408 6.601 1.00 5.43 ? 48 LEU A N 1 ATOM 117 C CA . LEU A 1 15 ? -13.383 15.126 5.582 1.00 5.73 ? 48 LEU A CA 1 ATOM 118 C C . LEU A 1 15 ? -13.158 13.755 5.004 1.00 6.37 ? 48 LEU A C 1 ATOM 119 O O . LEU A 1 15 ? -12.010 13.417 4.670 1.00 6.03 ? 48 LEU A O 1 ATOM 120 C CB . LEU A 1 15 ? -13.202 16.104 4.453 1.00 5.57 ? 48 LEU A CB 1 ATOM 121 C CG . LEU A 1 15 ? -14.007 15.849 3.201 1.00 5.43 ? 48 LEU A CG 1 ATOM 122 C CD1 . LEU A 1 15 ? -15.483 16.044 3.440 1.00 5.43 ? 48 LEU A CD1 1 ATOM 123 C CD2 . LEU A 1 15 ? -13.519 16.884 2.212 1.00 5.43 ? 48 LEU A CD2 1 ATOM 124 N N . ASP A 1 16 ? -14.233 12.975 4.876 1.00 7.27 ? 49 ASP A N 1 ATOM 125 C CA . ASP A 1 16 ? -14.183 11.770 4.078 1.00 8.36 ? 49 ASP A CA 1 ATOM 126 C C . ASP A 1 16 ? -14.958 11.991 2.798 1.00 8.90 ? 49 ASP A C 1 ATOM 127 O O . ASP A 1 16 ? -16.160 11.809 2.783 1.00 7.94 ? 49 ASP A O 1 ATOM 128 C CB . ASP A 1 16 ? -14.724 10.550 4.813 1.00 9.01 ? 49 ASP A CB 1 ATOM 129 C CG . ASP A 1 16 ? -14.407 9.222 4.082 1.00 9.70 ? 49 ASP A CG 1 ATOM 130 O OD1 . ASP A 1 16 ? -14.209 9.312 2.853 1.00 10.01 ? 49 ASP A OD1 1 ATOM 131 O OD2 . ASP A 1 16 ? -14.301 8.116 4.735 1.00 9.96 -1 49 ASP A OD2 1 ATOM 132 N N . PRO A 1 17 ? -14.278 12.334 1.734 1.00 10.44 ? 50 PRO A N 1 ATOM 133 C CA . PRO A 1 17 ? -14.882 12.588 0.437 1.00 11.35 ? 50 PRO A CA 1 ATOM 134 C C . PRO A 1 17 ? -15.657 11.416 -0.171 1.00 11.75 ? 50 PRO A C 1 ATOM 135 O O . PRO A 1 17 ? -16.388 11.580 -1.035 1.00 13.93 ? 50 PRO A O 1 ATOM 136 C CB . PRO A 1 17 ? -13.684 12.939 -0.394 1.00 11.24 ? 50 PRO A CB 1 ATOM 137 C CG . PRO A 1 17 ? -12.552 12.984 0.528 1.00 11.04 ? 50 PRO A CG 1 ATOM 138 C CD . PRO A 1 17 ? -12.870 12.049 1.570 1.00 10.58 ? 50 PRO A CD 1 ATOM 139 N N . THR A 1 18 ? -15.477 10.251 0.359 1.00 11.62 ? 51 THR A N 1 ATOM 140 C CA . THR A 1 18 ? -16.013 8.994 -0.017 1.00 10.33 ? 51 THR A CA 1 ATOM 141 C C . THR A 1 18 ? -17.391 8.706 0.528 1.00 10.78 ? 51 THR A C 1 ATOM 142 O O . THR A 1 18 ? -18.075 7.905 0.002 1.00 10.75 ? 51 THR A O 1 ATOM 143 C CB . THR A 1 18 ? -14.950 7.999 0.489 1.00 10.68 ? 51 THR A CB 1 ATOM 144 O OG1 . THR A 1 18 ? -14.093 7.652 -0.555 1.00 10.67 ? 51 THR A OG1 1 ATOM 145 C CG2 . THR A 1 18 ? -15.420 6.798 1.138 1.00 10.64 ? 51 THR A CG2 1 ATOM 146 N N . TYR A 1 19 ? -17.753 9.354 1.602 1.00 10.46 ? 52 TYR A N 1 ATOM 147 C CA . TYR A 1 19 ? -19.001 9.153 2.268 1.00 10.05 ? 52 TYR A CA 1 ATOM 148 C C . TYR A 1 19 ? -20.298 9.232 1.514 1.00 11.16 ? 52 TYR A C 1 ATOM 149 O O . TYR A 1 19 ? -20.605 10.185 0.895 1.00 11.15 ? 52 TYR A O 1 ATOM 150 C CB . TYR A 1 19 ? -19.095 10.051 3.511 1.00 9.37 ? 52 TYR A CB 1 ATOM 151 C CG . TYR A 1 19 ? -20.116 9.616 4.531 1.00 8.87 ? 52 TYR A CG 1 ATOM 152 C CD1 . TYR A 1 19 ? -21.433 9.906 4.390 1.00 8.76 ? 52 TYR A CD1 1 ATOM 153 C CD2 . TYR A 1 19 ? -19.761 8.890 5.600 1.00 8.71 ? 52 TYR A CD2 1 ATOM 154 C CE1 . TYR A 1 19 ? -22.343 9.467 5.290 1.00 8.35 ? 52 TYR A CE1 1 ATOM 155 C CE2 . TYR A 1 19 ? -20.672 8.475 6.505 1.00 8.49 ? 52 TYR A CE2 1 ATOM 156 C CZ . TYR A 1 19 ? -21.950 8.768 6.337 1.00 8.25 ? 52 TYR A CZ 1 ATOM 157 O OH . TYR A 1 19 ? -22.847 8.365 7.196 1.00 8.36 ? 52 TYR A OH 1 ATOM 158 N N . HIS A 1 20 ? -21.071 8.185 1.592 1.00 12.70 ? 53 HIS A N 1 ATOM 159 C CA . HIS A 1 20 ? -22.412 8.195 1.036 1.00 13.10 ? 53 HIS A CA 1 ATOM 160 C C . HIS A 1 20 ? -23.218 7.023 1.591 1.00 14.04 ? 53 HIS A C 1 ATOM 161 O O . HIS A 1 20 ? -22.701 5.930 1.764 1.00 13.82 ? 53 HIS A O 1 ATOM 162 C CB . HIS A 1 20 ? -22.355 8.107 -0.480 1.00 14.18 ? 53 HIS A CB 1 ATOM 163 C CG . HIS A 1 20 ? -21.920 6.776 -0.982 1.00 15.16 ? 53 HIS A CG 1 ATOM 164 N ND1 . HIS A 1 20 ? -20.697 6.233 -0.675 1.00 16.73 ? 53 HIS A ND1 1 ATOM 165 C CD2 . HIS A 1 20 ? -22.554 5.859 -1.736 1.00 16.48 ? 53 HIS A CD2 1 ATOM 166 C CE1 . HIS A 1 20 ? -20.575 5.043 -1.235 1.00 16.68 ? 53 HIS A CE1 1 ATOM 167 N NE2 . HIS A 1 20 ? -21.697 4.786 -1.873 1.00 17.86 ? 53 HIS A NE2 1 ATOM 168 N N . ILE A 1 21 ? -24.487 7.274 1.869 1.00 15.19 ? 54 ILE A N 1 ATOM 169 C CA . ILE A 1 21 ? -25.396 6.275 2.292 1.00 17.13 ? 54 ILE A CA 1 ATOM 170 C C . ILE A 1 21 ? -25.692 5.276 1.183 1.00 19.45 ? 54 ILE A C 1 ATOM 171 O O . ILE A 1 21 ? -26.132 5.661 0.103 1.00 21.27 ? 54 ILE A O 1 ATOM 172 C CB . ILE A 1 21 ? -26.752 6.892 2.685 1.00 18.71 ? 54 ILE A CB 1 ATOM 173 C CG1 . ILE A 1 21 ? -26.630 7.892 3.867 1.00 18.82 ? 54 ILE A CG1 1 ATOM 174 C CG2 . ILE A 1 21 ? -27.745 5.787 3.057 1.00 19.52 ? 54 ILE A CG2 1 ATOM 175 C CD1 . ILE A 1 21 ? -26.004 7.323 5.120 1.00 18.67 ? 54 ILE A CD1 1 ATOM 176 N N . THR A 1 22 ? -25.443 3.997 1.465 1.00 21.05 ? 55 THR A N 1 ATOM 177 C CA . THR A 1 22 ? -25.841 2.901 0.634 1.00 21.60 ? 55 THR A CA 1 ATOM 178 C C . THR A 1 22 ? -26.121 1.669 1.473 1.00 23.47 ? 55 THR A C 1 ATOM 179 O O . THR A 1 22 ? -25.790 1.615 2.653 1.00 24.09 ? 55 THR A O 1 ATOM 180 C CB . THR A 1 22 ? -24.751 2.530 -0.355 1.00 23.30 ? 55 THR A CB 1 ATOM 181 O OG1 . THR A 1 22 ? -25.104 1.299 -1.016 1.00 26.84 ? 55 THR A OG1 1 ATOM 182 C CG2 . THR A 1 22 ? -23.429 2.312 0.361 1.00 23.70 ? 55 THR A CG2 1 ATOM 183 N N . ASP A 1 23 ? -26.686 0.650 0.831 1.00 26.91 ? 56 ASP A N 1 ATOM 184 C CA . ASP A 1 23 ? -27.091 -0.591 1.503 1.00 29.91 ? 56 ASP A CA 1 ATOM 185 C C . ASP A 1 23 ? -25.952 -1.437 2.055 1.00 26.36 ? 56 ASP A C 1 ATOM 186 O O . ASP A 1 23 ? -26.159 -2.183 2.991 1.00 26.25 ? 56 ASP A O 1 ATOM 187 C CB . ASP A 1 23 ? -27.902 -1.471 0.539 1.00 35.37 ? 56 ASP A CB 1 ATOM 188 C CG . ASP A 1 23 ? -29.321 -0.965 0.351 1.00 42.46 ? 56 ASP A CG 1 ATOM 189 O OD1 . ASP A 1 23 ? -29.955 -0.576 1.372 1.00 44.30 ? 56 ASP A OD1 1 ATOM 190 O OD2 . ASP A 1 23 ? -29.792 -0.947 -0.815 1.00 45.38 -1 56 ASP A OD2 1 ATOM 191 N N . ASP A 1 24 ? -24.779 -1.374 1.435 1.00 22.52 ? 57 ASP A N 1 ATOM 192 C CA . ASP A 1 24 ? -23.646 -2.167 1.871 1.00 19.31 ? 57 ASP A CA 1 ATOM 193 C C . ASP A 1 24 ? -22.889 -1.239 2.791 1.00 16.82 ? 57 ASP A C 1 ATOM 194 O O . ASP A 1 24 ? -22.187 -0.361 2.328 1.00 16.51 ? 57 ASP A O 1 ATOM 195 C CB . ASP A 1 24 ? -22.774 -2.624 0.681 1.00 18.30 ? 57 ASP A CB 1 ATOM 196 C CG . ASP A 1 24 ? -21.592 -3.476 1.110 1.00 19.45 ? 57 ASP A CG 1 ATOM 197 O OD1 . ASP A 1 24 ? -21.166 -3.441 2.295 1.00 19.78 ? 57 ASP A OD1 1 ATOM 198 O OD2 . ASP A 1 24 ? -21.057 -4.206 0.260 1.00 20.12 -1 57 ASP A OD2 1 ATOM 199 N N . HIS A 1 25 ? -23.032 -1.458 4.090 1.00 14.77 ? 58 HIS A N 1 ATOM 200 C CA . HIS A 1 25 ? -22.439 -0.598 5.123 1.00 13.85 ? 58 HIS A CA 1 ATOM 201 C C . HIS A 1 25 ? -20.939 -0.719 5.195 1.00 13.07 ? 58 HIS A C 1 ATOM 202 O O . HIS A 1 25 ? -20.284 0.178 5.730 1.00 13.09 ? 58 HIS A O 1 ATOM 203 C CB . HIS A 1 25 ? -23.043 -0.881 6.501 1.00 14.39 ? 58 HIS A CB 1 ATOM 204 C CG . HIS A 1 25 ? -24.426 -0.331 6.704 1.00 14.41 ? 58 HIS A CG 1 ATOM 205 N ND1 . HIS A 1 25 ? -25.159 0.281 5.704 1.00 15.33 ? 58 HIS A ND1 1 ATOM 206 C CD2 . HIS A 1 25 ? -25.215 -0.329 7.796 1.00 14.71 ? 58 HIS A CD2 1 ATOM 207 C CE1 . HIS A 1 25 ? -26.329 0.656 6.181 1.00 15.06 ? 58 HIS A CE1 1 ATOM 208 N NE2 . HIS A 1 25 ? -26.372 0.325 7.459 1.00 14.77 ? 58 HIS A NE2 1 ATOM 209 N N . THR A 1 26 ? -20.375 -1.734 4.562 1.00 11.93 ? 59 THR A N 1 ATOM 210 C CA . THR A 1 26 ? -18.943 -1.721 4.359 1.00 12.42 ? 59 THR A CA 1 ATOM 211 C C . THR A 1 26 ? -18.505 -0.747 3.273 1.00 13.45 ? 59 THR A C 1 ATOM 212 O O . THR A 1 26 ? -17.300 -0.499 3.122 1.00 14.44 ? 59 THR A O 1 ATOM 213 C CB . THR A 1 26 ? -18.328 -3.095 4.009 1.00 11.79 ? 59 THR A CB 1 ATOM 214 O OG1 . THR A 1 26 ? -18.706 -3.454 2.692 1.00 11.87 ? 59 THR A OG1 1 ATOM 215 C CG2 . THR A 1 26 ? -18.798 -4.150 4.941 1.00 11.69 ? 59 THR A CG2 1 ATOM 216 N N . LYS A 1 27 ? -19.432 -0.189 2.519 1.00 14.47 ? 60 LYS A N 1 ATOM 217 C CA . LYS A 1 27 ? -19.055 0.696 1.394 1.00 15.79 ? 60 LYS A CA 1 ATOM 218 C C . LYS A 1 27 ? -19.449 2.147 1.638 1.00 13.77 ? 60 LYS A C 1 ATOM 219 O O . LYS A 1 27 ? -19.366 2.956 0.741 1.00 14.69 ? 60 LYS A O 1 ATOM 220 C CB . LYS A 1 27 ? -19.748 0.231 0.072 1.00 18.00 ? 60 LYS A CB 1 ATOM 221 C CG . LYS A 1 27 ? -19.411 -1.188 -0.404 1.00 21.52 ? 60 LYS A CG 1 ATOM 222 C CD . LYS A 1 27 ? -18.249 -1.178 -1.396 1.00 25.21 ? 60 LYS A CD 1 ATOM 223 C CE . LYS A 1 27 ? -17.540 -2.527 -1.546 1.00 28.28 ? 60 LYS A CE 1 ATOM 224 N NZ . LYS A 1 27 ? -18.419 -3.439 -2.338 1.00 31.24 1 60 LYS A NZ 1 ATOM 225 N N . VAL A 1 28 ? -19.961 2.460 2.808 1.00 11.85 ? 61 VAL A N 1 ATOM 226 C CA . VAL A 1 28 ? -20.387 3.800 3.118 1.00 10.60 ? 61 VAL A CA 1 ATOM 227 C C . VAL A 1 28 ? -19.248 4.782 3.172 1.00 9.74 ? 61 VAL A C 1 ATOM 228 O O . VAL A 1 28 ? -19.372 5.919 2.708 1.00 9.89 ? 61 VAL A O 1 ATOM 229 C CB . VAL A 1 28 ? -21.088 3.789 4.462 1.00 10.90 ? 61 VAL A CB 1 ATOM 230 C CG1 . VAL A 1 28 ? -21.166 5.158 5.081 1.00 11.03 ? 61 VAL A CG1 1 ATOM 231 C CG2 . VAL A 1 28 ? -22.481 3.222 4.294 1.00 11.25 ? 61 VAL A CG2 1 ATOM 232 N N . CYS A 1 29 ? -18.127 4.363 3.717 1.00 8.79 ? 62 CYS A N 1 ATOM 233 C CA . CYS A 1 29 ? -17.014 5.275 3.854 1.00 8.50 ? 62 CYS A CA 1 ATOM 234 C C . CYS A 1 29 ? -15.717 4.526 3.839 1.00 8.16 ? 62 CYS A C 1 ATOM 235 O O . CYS A 1 29 ? -15.542 3.603 4.597 1.00 8.98 ? 62 CYS A O 1 ATOM 236 C CB . CYS A 1 29 ? -17.151 6.025 5.198 1.00 8.78 ? 62 CYS A CB 1 ATOM 237 S SG . CYS A 1 29 ? -17.071 4.988 6.705 1.00 8.40 ? 62 CYS A SG 1 ATOM 238 N N . ALA A 1 30 ? -14.788 4.913 3.008 1.00 7.76 ? 63 ALA A N 1 ATOM 239 C CA . ALA A 1 30 ? -13.483 4.303 3.002 1.00 7.86 ? 63 ALA A CA 1 ATOM 240 C C . ALA A 1 30 ? -12.804 4.375 4.381 1.00 8.28 ? 63 ALA A C 1 ATOM 241 O O . ALA A 1 30 ? -12.124 3.457 4.767 1.00 8.53 ? 63 ALA A O 1 ATOM 242 C CB . ALA A 1 30 ? -12.605 4.974 1.991 1.00 7.66 ? 63 ALA A CB 1 ATOM 243 N N . SER A 1 31 ? -12.986 5.454 5.128 1.00 8.53 ? 64 SER A N 1 ATOM 244 C CA . SER A 1 31 ? -12.460 5.514 6.495 1.00 8.59 ? 64 SER A CA 1 ATOM 245 C C . SER A 1 31 ? -12.908 4.409 7.493 1.00 8.18 ? 64 SER A C 1 ATOM 246 O O . SER A 1 31 ? -12.335 4.286 8.555 1.00 8.37 ? 64 SER A O 1 ATOM 247 C CB . SER A 1 31 ? -12.744 6.908 7.109 1.00 9.09 ? 64 SER A CB 1 ATOM 248 O OG . SER A 1 31 ? -14.136 7.233 7.128 1.00 9.19 ? 64 SER A OG 1 ATOM 249 N N . SER A 1 32 ? -13.899 3.595 7.196 1.00 7.94 ? 65 SER A N 1 ATOM 250 C CA . SER A 1 32 ? -14.176 2.458 8.070 1.00 7.93 ? 65 SER A CA 1 ATOM 251 C C . SER A 1 32 ? -13.291 1.283 7.714 1.00 8.85 ? 65 SER A C 1 ATOM 252 O O . SER A 1 32 ? -13.359 0.239 8.356 1.00 9.05 ? 65 SER A O 1 ATOM 253 C CB . SER A 1 32 ? -15.623 2.027 7.945 1.00 7.93 ? 65 SER A CB 1 ATOM 254 O OG . SER A 1 32 ? -15.885 1.138 6.839 1.00 8.11 ? 65 SER A OG 1 ATOM 255 N N . LYS A 1 33 ? -12.524 1.421 6.630 1.00 9.64 ? 66 LYS A N 1 ATOM 256 C CA . LYS A 1 33 ? -11.599 0.398 6.151 1.00 10.38 ? 66 LYS A CA 1 ATOM 257 C C . LYS A 1 33 ? -12.205 -0.957 6.022 1.00 10.27 ? 66 LYS A C 1 ATOM 258 O O . LYS A 1 33 ? -11.585 -1.958 6.363 1.00 10.91 ? 66 LYS A O 1 ATOM 259 C CB . LYS A 1 33 ? -10.319 0.338 6.987 1.00 10.95 ? 66 LYS A CB 1 ATOM 260 C CG . LYS A 1 33 ? -9.620 1.695 7.046 1.00 12.26 ? 66 LYS A CG 1 ATOM 261 C CD . LYS A 1 33 ? -8.485 1.710 8.045 1.00 14.11 ? 66 LYS A CD 1 ATOM 262 C CE . LYS A 1 33 ? -8.476 2.984 8.912 1.00 16.18 ? 66 LYS A CE 1 ATOM 263 N NZ . LYS A 1 33 ? -9.795 3.600 9.292 1.00 16.98 1 66 LYS A NZ 1 ATOM 264 N N . GLY A 1 34 ? -13.399 -0.998 5.490 1.00 9.86 ? 67 GLY A N 1 ATOM 265 C CA . GLY A 1 34 ? -14.025 -2.264 5.269 1.00 10.40 ? 67 GLY A CA 1 ATOM 266 C C . GLY A 1 34 ? -14.951 -2.703 6.363 1.00 11.57 ? 67 GLY A C 1 ATOM 267 O O . GLY A 1 34 ? -15.806 -3.527 6.117 1.00 13.79 ? 67 GLY A O 1 ATOM 268 N N . ALA A 1 35 ? -14.857 -2.152 7.565 1.00 12.12 ? 68 ALA A N 1 ATOM 269 C CA . ALA A 1 35 ? -15.845 -2.489 8.605 1.00 12.19 ? 68 ALA A CA 1 ATOM 270 C C . ALA A 1 35 ? -17.202 -1.942 8.228 1.00 12.49 ? 68 ALA A C 1 ATOM 271 O O . ALA A 1 35 ? -17.284 -1.015 7.453 1.00 13.00 ? 68 ALA A O 1 ATOM 272 C CB . ALA A 1 35 ? -15.407 -1.970 9.947 1.00 11.89 ? 68 ALA A CB 1 ATOM 273 N N . ASN A 1 36 ? -18.245 -2.587 8.708 1.00 12.81 ? 69 ASN A N 1 ATOM 274 C CA . ASN A 1 36 ? -19.600 -2.147 8.529 1.00 13.62 ? 69 ASN A CA 1 ATOM 275 C C . ASN A 1 36 ? -19.806 -0.919 9.367 1.00 13.77 ? 69 ASN A C 1 ATOM 276 O O . ASN A 1 36 ? -19.729 -0.954 10.590 1.00 14.85 ? 69 ASN A O 1 ATOM 277 C CB . ASN A 1 36 ? -20.616 -3.225 8.984 1.00 14.42 ? 69 ASN A CB 1 ATOM 278 C CG . ASN A 1 36 ? -21.178 -4.028 7.849 1.00 16.87 ? 69 ASN A CG 1 ATOM 279 O OD1 . ASN A 1 36 ? -21.543 -3.510 6.819 1.00 19.64 ? 69 ASN A OD1 1 ATOM 280 N ND2 . ASN A 1 36 ? -21.244 -5.298 8.025 1.00 21.39 ? 69 ASN A ND2 1 ATOM 281 N N . ALA A 1 37 ? -20.117 0.175 8.720 1.00 14.26 ? 70 ALA A N 1 ATOM 282 C CA . ALA A 1 37 ? -20.535 1.360 9.415 1.00 14.04 ? 70 ALA A CA 1 ATOM 283 C C . ALA A 1 37 ? -21.670 0.944 10.333 1.00 14.95 ? 70 ALA A C 1 ATOM 284 O O . ALA A 1 37 ? -22.474 0.051 10.011 1.00 14.41 ? 70 ALA A O 1 ATOM 285 C CB . ALA A 1 37 ? -20.965 2.451 8.444 1.00 13.78 ? 70 ALA A CB 1 ATOM 286 N N . SER A 1 38 ? -21.705 1.591 11.493 1.00 15.17 ? 71 SER A N 1 ATOM 287 C CA . SER A 1 38 ? -22.491 1.122 12.575 1.00 15.81 ? 71 SER A CA 1 ATOM 288 C C . SER A 1 38 ? -23.952 1.411 12.337 1.00 16.90 ? 71 SER A C 1 ATOM 289 O O . SER A 1 38 ? -24.775 0.522 12.392 1.00 18.80 ? 71 SER A O 1 ATOM 290 C CB . SER A 1 38 ? -22.023 1.791 13.858 1.00 16.63 ? 71 SER A CB 1 ATOM 291 O OG . SER A 1 38 ? -22.876 1.422 14.937 1.00 17.30 ? 71 SER A OG 1 ATOM 292 N N . ASN A 1 39 ? -24.284 2.669 12.103 1.00 17.94 ? 72 ASN A N 1 ATOM 293 C CA . ASN A 1 39 ? -25.662 3.071 11.898 1.00 18.69 ? 72 ASN A CA 1 ATOM 294 C C . ASN A 1 39 ? -25.651 4.393 11.194 1.00 15.92 ? 72 ASN A C 1 ATOM 295 O O . ASN A 1 39 ? -25.926 5.387 11.773 1.00 15.59 ? 72 ASN A O 1 ATOM 296 C CB . ASN A 1 39 ? -26.390 3.164 13.212 1.00 22.91 ? 72 ASN A CB 1 ATOM 297 C CG . ASN A 1 39 ? -27.895 3.221 13.052 1.00 28.24 ? 72 ASN A CG 1 ATOM 298 O OD1 . ASN A 1 39 ? -28.478 2.657 12.131 1.00 33.52 ? 72 ASN A OD1 1 ATOM 299 N ND2 . ASN A 1 39 ? -28.535 3.895 13.978 1.00 34.15 ? 72 ASN A ND2 1 ATOM 300 N N . PRO A 1 40 ? -25.300 4.381 9.912 1.00 13.35 ? 73 PRO A N 1 ATOM 301 C CA . PRO A 1 40 ? -24.889 5.583 9.293 1.00 12.44 ? 73 PRO A CA 1 ATOM 302 C C . PRO A 1 40 ? -26.032 6.447 8.926 1.00 11.30 ? 73 PRO A C 1 ATOM 303 O O . PRO A 1 40 ? -27.066 5.952 8.625 1.00 10.82 ? 73 PRO A O 1 ATOM 304 C CB . PRO A 1 40 ? -24.152 5.095 8.046 1.00 12.47 ? 73 PRO A CB 1 ATOM 305 C CG . PRO A 1 40 ? -24.814 3.811 7.712 1.00 12.56 ? 73 PRO A CG 1 ATOM 306 C CD . PRO A 1 40 ? -25.133 3.212 9.028 1.00 12.88 ? 73 PRO A CD 1 ATOM 307 N N . GLY A 1 41 ? -25.795 7.748 8.921 1.00 10.94 ? 74 GLY A N 1 ATOM 308 C CA . GLY A 1 41 ? -26.820 8.716 8.638 1.00 10.21 ? 74 GLY A CA 1 ATOM 309 C C . GLY A 1 41 ? -26.288 9.877 7.885 1.00 10.07 ? 74 GLY A C 1 ATOM 310 O O . GLY A 1 41 ? -25.140 9.907 7.471 1.00 9.95 ? 74 GLY A O 1 ATOM 311 N N . PRO A 1 42 ? -27.145 10.843 7.651 1.00 10.43 ? 75 PRO A N 1 ATOM 312 C CA . PRO A 1 42 ? -26.757 11.918 6.753 1.00 10.51 ? 75 PRO A CA 1 ATOM 313 C C . PRO A 1 42 ? -25.674 12.742 7.368 1.00 10.96 ? 75 PRO A C 1 ATOM 314 O O . PRO A 1 42 ? -24.901 13.395 6.628 1.00 11.57 ? 75 PRO A O 1 ATOM 315 C CB . PRO A 1 42 ? -28.024 12.721 6.584 1.00 10.30 ? 75 PRO A CB 1 ATOM 316 C CG . PRO A 1 42 ? -28.899 12.302 7.721 1.00 10.64 ? 75 PRO A CG 1 ATOM 317 C CD . PRO A 1 42 ? -28.564 10.886 8.006 1.00 10.33 ? 75 PRO A CD 1 ATOM 318 N N . PHE A 1 43 ? -25.543 12.704 8.699 1.00 10.96 ? 76 PHE A N 1 ATOM 319 C CA . PHE A 1 43 ? -24.435 13.477 9.327 1.00 10.57 ? 76 PHE A CA 1 ATOM 320 C C . PHE A 1 43 ? -23.182 12.706 9.735 1.00 9.98 ? 76 PHE A C 1 ATOM 321 O O . PHE A 1 43 ? -22.281 13.304 10.303 1.00 10.76 ? 76 PHE A O 1 ATOM 322 C CB . PHE A 1 43 ? -24.983 14.295 10.467 1.00 10.77 ? 76 PHE A CB 1 ATOM 323 C CG . PHE A 1 43 ? -25.990 15.307 10.008 1.00 10.86 ? 76 PHE A CG 1 ATOM 324 C CD1 . PHE A 1 43 ? -25.577 16.462 9.379 1.00 10.94 ? 76 PHE A CD1 1 ATOM 325 C CD2 . PHE A 1 43 ? -27.323 15.082 10.157 1.00 11.04 ? 76 PHE A CD2 1 ATOM 326 C CE1 . PHE A 1 43 ? -26.489 17.389 8.925 1.00 11.22 ? 76 PHE A CE1 1 ATOM 327 C CE2 . PHE A 1 43 ? -28.246 15.989 9.688 1.00 11.52 ? 76 PHE A CE2 1 ATOM 328 C CZ . PHE A 1 43 ? -27.827 17.145 9.053 1.00 11.13 ? 76 PHE A CZ 1 ATOM 329 N N . GLY A 1 44 ? -23.109 11.416 9.404 1.00 8.69 ? 77 GLY A N 1 ATOM 330 C CA . GLY A 1 44 ? -21.948 10.617 9.686 1.00 8.26 ? 77 GLY A CA 1 ATOM 331 C C . GLY A 1 44 ? -22.212 9.331 10.456 1.00 7.93 ? 77 GLY A C 1 ATOM 332 O O . GLY A 1 44 ? -23.353 8.900 10.651 1.00 7.73 ? 77 GLY A O 1 ATOM 333 N N . ASP A 1 45 ? -21.130 8.719 10.900 1.00 7.31 ? 78 ASP A N 1 ATOM 334 C CA . ASP A 1 45 ? -21.213 7.494 11.622 1.00 7.13 ? 78 ASP A CA 1 ATOM 335 C C . ASP A 1 45 ? -19.969 7.466 12.481 1.00 6.89 ? 78 ASP A C 1 ATOM 336 O O . ASP A 1 45 ? -18.943 8.077 12.137 1.00 6.38 ? 78 ASP A O 1 ATOM 337 C CB . ASP A 1 45 ? -21.248 6.328 10.660 1.00 7.42 ? 78 ASP A CB 1 ATOM 338 C CG . ASP A 1 45 ? -21.419 5.006 11.349 1.00 7.79 ? 78 ASP A CG 1 ATOM 339 O OD1 . ASP A 1 45 ? -22.603 4.708 11.665 1.00 7.79 ? 78 ASP A OD1 1 ATOM 340 O OD2 . ASP A 1 45 ? -20.374 4.287 11.578 1.00 7.49 -1 78 ASP A OD2 1 ATOM 341 N N . VAL A 1 46 ? -20.083 6.802 13.626 1.00 6.88 ? 79 VAL A N 1 ATOM 342 C CA . VAL A 1 46 ? -18.953 6.687 14.554 1.00 6.94 ? 79 VAL A CA 1 ATOM 343 C C . VAL A 1 46 ? -17.801 5.888 13.987 1.00 6.93 ? 79 VAL A C 1 ATOM 344 O O . VAL A 1 46 ? -16.671 6.043 14.448 1.00 7.96 ? 79 VAL A O 1 ATOM 345 C CB . VAL A 1 46 ? -19.357 6.143 15.945 1.00 7.00 ? 79 VAL A CB 1 ATOM 346 C CG1 . VAL A 1 46 ? -20.357 7.079 16.613 1.00 6.86 ? 79 VAL A CG1 1 ATOM 347 C CG2 . VAL A 1 46 ? -19.972 4.740 15.885 1.00 6.93 ? 79 VAL A CG2 1 ATOM 348 N N . LEU A 1 47 ? -18.035 5.077 12.966 1.00 6.68 ? 80 LEU A N 1 ATOM 349 C CA . LEU A 1 47 ? -16.955 4.335 12.346 1.00 6.58 ? 80 LEU A CA 1 ATOM 350 C C . LEU A 1 47 ? -16.432 5.049 11.081 1.00 6.96 ? 80 LEU A C 1 ATOM 351 O O . LEU A 1 47 ? -15.588 4.495 10.372 1.00 6.89 ? 80 LEU A O 1 ATOM 352 C CB . LEU A 1 47 ? -17.460 2.918 12.022 1.00 6.52 ? 80 LEU A CB 1 ATOM 353 C CG . LEU A 1 47 ? -17.185 1.752 13.009 1.00 6.59 ? 80 LEU A CG 1 ATOM 354 C CD1 . LEU A 1 47 ? -16.709 2.121 14.417 1.00 6.57 ? 80 LEU A CD1 1 ATOM 355 C CD2 . LEU A 1 47 ? -18.344 0.839 13.150 1.00 6.49 ? 80 LEU A CD2 1 ATOM 356 N N . CYS A 1 48 ? -16.945 6.255 10.783 1.00 7.00 ? 81 CYS A N 1 ATOM 357 C CA . CYS A 1 48 ? -16.503 7.014 9.645 1.00 7.26 ? 81 CYS A CA 1 ATOM 358 C C . CYS A 1 48 ? -15.950 8.416 9.971 1.00 6.85 ? 81 CYS A C 1 ATOM 359 O O . CYS A 1 48 ? -16.264 9.013 10.969 1.00 6.56 ? 81 CYS A O 1 ATOM 360 C CB . CYS A 1 48 ? -17.631 7.224 8.656 1.00 7.87 ? 81 CYS A CB 1 ATOM 361 S SG . CYS A 1 48 ? -18.459 5.793 7.949 1.00 9.34 ? 81 CYS A SG 1 ATOM 362 N N . ASP A 1 49 ? -15.154 8.961 9.056 1.00 6.53 ? 82 ASP A N 1 ATOM 363 C CA . ASP A 1 49 ? -14.713 10.335 9.187 1.00 6.24 ? 82 ASP A CA 1 ATOM 364 C C . ASP A 1 49 ? -15.860 11.219 8.670 1.00 6.25 ? 82 ASP A C 1 ATOM 365 O O . ASP A 1 49 ? -16.907 10.689 8.327 1.00 6.25 ? 82 ASP A O 1 ATOM 366 C CB . ASP A 1 49 ? -13.374 10.516 8.463 1.00 6.02 ? 82 ASP A CB 1 ATOM 367 C CG . ASP A 1 49 ? -12.169 10.480 9.436 1.00 5.87 ? 82 ASP A CG 1 ATOM 368 O OD1 . ASP A 1 49 ? -12.347 11.025 10.543 1.00 5.67 ? 82 ASP A OD1 1 ATOM 369 O OD2 . ASP A 1 49 ? -11.072 9.935 9.124 1.00 5.42 -1 82 ASP A OD2 1 ATOM 370 N N . SER A 1 50 ? -15.697 12.539 8.671 1.00 6.21 ? 83 SER A N 1 ATOM 371 C CA . SER A 1 50 ? -16.808 13.449 8.489 1.00 6.27 ? 83 SER A CA 1 ATOM 372 C C . SER A 1 50 ? -17.280 13.492 7.060 1.00 6.69 ? 83 SER A C 1 ATOM 373 O O . SER A 1 50 ? -16.497 13.726 6.169 1.00 6.76 ? 83 SER A O 1 ATOM 374 C CB . SER A 1 50 ? -16.382 14.866 8.811 1.00 6.22 ? 83 SER A CB 1 ATOM 375 O OG . SER A 1 50 ? -15.829 14.970 10.104 1.00 6.22 ? 83 SER A OG 1 ATOM 376 N N . PRO A 1 51 ? -18.576 13.319 6.827 1.00 7.04 ? 84 PRO A N 1 ATOM 377 C CA . PRO A 1 51 ? -19.043 13.692 5.499 1.00 7.40 ? 84 PRO A CA 1 ATOM 378 C C . PRO A 1 51 ? -19.050 15.182 5.343 1.00 8.36 ? 84 PRO A C 1 ATOM 379 O O . PRO A 1 51 ? -19.082 15.906 6.327 1.00 8.57 ? 84 PRO A O 1 ATOM 380 C CB . PRO A 1 51 ? -20.479 13.200 5.469 1.00 7.15 ? 84 PRO A CB 1 ATOM 381 C CG . PRO A 1 51 ? -20.858 12.975 6.890 1.00 7.18 ? 84 PRO A CG 1 ATOM 382 C CD . PRO A 1 51 ? -19.607 12.665 7.641 1.00 6.98 ? 84 PRO A CD 1 ATOM 383 N N . TYR A 1 52 ? -19.064 15.649 4.107 1.00 9.57 ? 85 TYR A N 1 ATOM 384 C CA . TYR A 1 52 ? -19.097 17.068 3.839 1.00 10.44 ? 85 TYR A CA 1 ATOM 385 C C . TYR A 1 52 ? -20.253 17.763 4.567 1.00 10.83 ? 85 TYR A C 1 ATOM 386 O O . TYR A 1 52 ? -20.066 18.818 5.150 1.00 10.71 ? 85 TYR A O 1 ATOM 387 C CB . TYR A 1 52 ? -19.147 17.324 2.325 1.00 10.98 ? 85 TYR A CB 1 ATOM 388 C CG . TYR A 1 52 ? -18.863 18.771 1.980 1.00 11.62 ? 85 TYR A CG 1 ATOM 389 C CD1 . TYR A 1 52 ? -17.622 19.335 2.232 1.00 11.88 ? 85 TYR A CD1 1 ATOM 390 C CD2 . TYR A 1 52 ? -19.835 19.563 1.406 1.00 12.19 ? 85 TYR A CD2 1 ATOM 391 C CE1 . TYR A 1 52 ? -17.368 20.652 1.919 1.00 12.52 ? 85 TYR A CE1 1 ATOM 392 C CE2 . TYR A 1 52 ? -19.597 20.876 1.080 1.00 12.32 ? 85 TYR A CE2 1 ATOM 393 C CZ . TYR A 1 52 ? -18.378 21.422 1.356 1.00 12.69 ? 85 TYR A CZ 1 ATOM 394 O OH . TYR A 1 52 ? -18.156 22.738 1.077 1.00 13.16 ? 85 TYR A OH 1 ATOM 395 N N . GLN A 1 53 ? -21.419 17.130 4.593 1.00 11.30 ? 86 GLN A N 1 ATOM 396 C CA . GLN A 1 53 ? -22.606 17.716 5.182 1.00 12.39 ? 86 GLN A CA 1 ATOM 397 C C . GLN A 1 53 ? -22.380 18.057 6.663 1.00 11.59 ? 86 GLN A C 1 ATOM 398 O O . GLN A 1 53 ? -22.915 19.050 7.183 1.00 11.24 ? 86 GLN A O 1 ATOM 399 C CB . GLN A 1 53 ? -23.758 16.740 4.992 1.00 15.85 ? 86 GLN A CB 1 ATOM 400 C CG . GLN A 1 53 ? -25.129 17.230 5.367 1.00 21.71 ? 86 GLN A CG 1 ATOM 401 C CD . GLN A 1 53 ? -26.225 16.718 4.394 1.00 31.67 ? 86 GLN A CD 1 ATOM 402 O OE1 . GLN A 1 53 ? -26.782 17.495 3.573 1.00 43.71 ? 86 GLN A OE1 1 ATOM 403 N NE2 . GLN A 1 53 ? -26.522 15.414 4.445 1.00 34.29 ? 86 GLN A NE2 1 ATOM 404 N N . LEU A 1 54 ? -21.598 17.230 7.360 1.00 10.12 ? 87 LEU A N 1 ATOM 405 C CA . LEU A 1 54 ? -21.335 17.443 8.776 1.00 9.38 ? 87 LEU A CA 1 ATOM 406 C C . LEU A 1 54 ? -20.507 18.694 8.966 1.00 9.13 ? 87 LEU A C 1 ATOM 407 O O . LEU A 1 54 ? -20.841 19.572 9.790 1.00 8.99 ? 87 LEU A O 1 ATOM 408 C CB . LEU A 1 54 ? -20.628 16.225 9.391 1.00 9.16 ? 87 LEU A CB 1 ATOM 409 C CG . LEU A 1 54 ? -20.072 16.413 10.781 1.00 8.87 ? 87 LEU A CG 1 ATOM 410 C CD1 . LEU A 1 54 ? -21.158 16.619 11.827 1.00 8.77 ? 87 LEU A CD1 1 ATOM 411 C CD2 . LEU A 1 54 ? -19.313 15.156 11.109 1.00 9.03 ? 87 LEU A CD2 1 ATOM 412 N N . ILE A 1 55 ? -19.467 18.788 8.156 1.00 8.62 ? 88 ILE A N 1 ATOM 413 C CA . ILE A 1 55 ? -18.590 19.945 8.158 1.00 8.51 ? 88 ILE A CA 1 ATOM 414 C C . ILE A 1 55 ? -19.316 21.214 7.805 1.00 8.66 ? 88 ILE A C 1 ATOM 415 O O . ILE A 1 55 ? -19.151 22.260 8.432 1.00 8.04 ? 88 ILE A O 1 ATOM 416 C CB . ILE A 1 55 ? -17.388 19.728 7.229 1.00 7.93 ? 88 ILE A CB 1 ATOM 417 C CG1 . ILE A 1 55 ? -16.496 18.725 7.909 1.00 8.17 ? 88 ILE A CG1 1 ATOM 418 C CG2 . ILE A 1 55 ? -16.590 20.987 7.101 1.00 7.83 ? 88 ILE A CG2 1 ATOM 419 C CD1 . ILE A 1 55 ? -15.548 17.949 7.036 1.00 8.31 ? 88 ILE A CD1 1 ATOM 420 N N . LEU A 1 56 ? -20.108 21.111 6.772 1.00 9.35 ? 89 LEU A N 1 ATOM 421 C CA . LEU A 1 56 ? -20.890 22.265 6.320 1.00 10.34 ? 89 LEU A CA 1 ATOM 422 C C . LEU A 1 56 ? -21.850 22.713 7.455 1.00 9.48 ? 89 LEU A C 1 ATOM 423 O O . LEU A 1 56 ? -21.974 23.899 7.731 1.00 9.28 ? 89 LEU A O 1 ATOM 424 C CB . LEU A 1 56 ? -21.615 21.910 5.016 1.00 11.29 ? 89 LEU A CB 1 ATOM 425 C CG . LEU A 1 56 ? -22.187 22.978 4.101 1.00 13.07 ? 89 LEU A CG 1 ATOM 426 C CD1 . LEU A 1 56 ? -21.159 24.061 3.747 1.00 14.08 ? 89 LEU A CD1 1 ATOM 427 C CD2 . LEU A 1 56 ? -22.727 22.298 2.816 1.00 13.04 ? 89 LEU A CD2 1 ATOM 428 N N . SER A 1 57 ? -22.442 21.758 8.162 1.00 8.77 ? 90 SER A N 1 ATOM 429 C CA . SER A 1 57 ? -23.366 22.093 9.213 1.00 8.57 ? 90 SER A CA 1 ATOM 430 C C . SER A 1 57 ? -22.674 22.777 10.375 1.00 8.58 ? 90 SER A C 1 ATOM 431 O O . SER A 1 57 ? -23.264 23.603 11.061 1.00 8.31 ? 90 SER A O 1 ATOM 432 C CB . SER A 1 57 ? -24.079 20.858 9.741 1.00 8.63 ? 90 SER A CB 1 ATOM 433 O OG . SER A 1 57 ? -23.294 20.235 10.723 1.00 8.89 ? 90 SER A OG 1 ATOM 434 N N . ALA A 1 58 ? -21.431 22.411 10.633 1.00 8.67 ? 91 ALA A N 1 ATOM 435 C CA . ALA A 1 58 ? -20.739 23.065 11.700 1.00 8.92 ? 91 ALA A CA 1 ATOM 436 C C . ALA A 1 58 ? -20.529 24.528 11.352 1.00 8.96 ? 91 ALA A C 1 ATOM 437 O O . ALA A 1 58 ? -20.712 25.382 12.163 1.00 8.37 ? 91 ALA A O 1 ATOM 438 C CB . ALA A 1 58 ? -19.426 22.380 11.976 1.00 9.01 ? 91 ALA A CB 1 ATOM 439 N N . PHE A 1 59 ? -20.168 24.803 10.117 1.00 10.21 ? 92 PHE A N 1 ATOM 440 C CA . PHE A 1 59 ? -19.863 26.173 9.703 1.00 11.08 ? 92 PHE A CA 1 ATOM 441 C C . PHE A 1 59 ? -21.162 26.969 9.540 1.00 11.47 ? 92 PHE A C 1 ATOM 442 O O . PHE A 1 59 ? -21.231 28.159 9.781 1.00 10.75 ? 92 PHE A O 1 ATOM 443 C CB . PHE A 1 59 ? -19.028 26.148 8.434 1.00 11.13 ? 92 PHE A CB 1 ATOM 444 C CG . PHE A 1 59 ? -17.602 25.699 8.646 1.00 11.14 ? 92 PHE A CG 1 ATOM 445 C CD1 . PHE A 1 59 ? -16.798 26.309 9.572 1.00 11.57 ? 92 PHE A CD1 1 ATOM 446 C CD2 . PHE A 1 59 ? -17.047 24.751 7.848 1.00 11.89 ? 92 PHE A CD2 1 ATOM 447 C CE1 . PHE A 1 59 ? -15.482 25.937 9.747 1.00 11.50 ? 92 PHE A CE1 1 ATOM 448 C CE2 . PHE A 1 59 ? -15.731 24.376 8.010 1.00 11.87 ? 92 PHE A CE2 1 ATOM 449 C CZ . PHE A 1 59 ? -14.958 24.959 8.970 1.00 11.45 ? 92 PHE A CZ 1 ATOM 450 N N . ASP A 1 60 ? -22.215 26.249 9.217 1.00 12.86 ? 93 ASP A N 1 ATOM 451 C CA . ASP A 1 60 ? -23.535 26.825 9.105 1.00 14.27 ? 93 ASP A CA 1 ATOM 452 C C . ASP A 1 60 ? -24.066 27.255 10.490 1.00 14.12 ? 93 ASP A C 1 ATOM 453 O O . ASP A 1 60 ? -24.632 28.341 10.630 1.00 14.47 ? 93 ASP A O 1 ATOM 454 C CB . ASP A 1 60 ? -24.452 25.845 8.405 1.00 15.28 ? 93 ASP A CB 1 ATOM 455 C CG . ASP A 1 60 ? -25.811 26.402 8.205 1.00 19.08 ? 93 ASP A CG 1 ATOM 456 O OD1 . ASP A 1 60 ? -25.947 27.377 7.444 1.00 24.23 ? 93 ASP A OD1 1 ATOM 457 O OD2 . ASP A 1 60 ? -26.793 25.899 8.798 1.00 22.43 -1 93 ASP A OD2 1 ATOM 458 N N . PHE A 1 61 ? -23.868 26.417 11.513 1.00 13.05 ? 94 PHE A N 1 ATOM 459 C CA . PHE A 1 61 ? -24.193 26.781 12.876 1.00 12.31 ? 94 PHE A CA 1 ATOM 460 C C . PHE A 1 61 ? -23.382 28.038 13.276 1.00 12.28 ? 94 PHE A C 1 ATOM 461 O O . PHE A 1 61 ? -23.884 29.013 13.800 1.00 11.41 ? 94 PHE A O 1 ATOM 462 C CB . PHE A 1 61 ? -23.858 25.629 13.832 1.00 12.88 ? 94 PHE A CB 1 ATOM 463 C CG . PHE A 1 61 ? -23.802 26.064 15.250 1.00 12.93 ? 94 PHE A CG 1 ATOM 464 C CD1 . PHE A 1 61 ? -24.949 26.460 15.892 1.00 13.22 ? 94 PHE A CD1 1 ATOM 465 C CD2 . PHE A 1 61 ? -22.608 26.247 15.870 1.00 12.78 ? 94 PHE A CD2 1 ATOM 466 C CE1 . PHE A 1 61 ? -24.899 26.956 17.180 1.00 13.69 ? 94 PHE A CE1 1 ATOM 467 C CE2 . PHE A 1 61 ? -22.534 26.746 17.143 1.00 13.02 ? 94 PHE A CE2 1 ATOM 468 C CZ . PHE A 1 61 ? -23.689 27.092 17.810 1.00 13.33 ? 94 PHE A CZ 1 ATOM 469 N N . ILE A 1 62 ? -22.108 28.013 13.039 1.00 12.37 ? 95 ILE A N 1 ATOM 470 C CA . ILE A 1 62 ? -21.356 29.166 13.340 1.00 14.17 ? 95 ILE A CA 1 ATOM 471 C C . ILE A 1 62 ? -22.016 30.413 12.737 1.00 16.09 ? 95 ILE A C 1 ATOM 472 O O . ILE A 1 62 ? -22.398 31.322 13.442 1.00 14.24 ? 95 ILE A O 1 ATOM 473 C CB . ILE A 1 62 ? -19.912 28.998 12.882 1.00 14.26 ? 95 ILE A CB 1 ATOM 474 C CG1 . ILE A 1 62 ? -19.167 28.097 13.875 1.00 14.18 ? 95 ILE A CG1 1 ATOM 475 C CG2 . ILE A 1 62 ? -19.216 30.356 12.814 1.00 14.90 ? 95 ILE A CG2 1 ATOM 476 C CD1 . ILE A 1 62 ? -17.736 27.825 13.469 1.00 14.87 ? 95 ILE A CD1 1 ATOM 477 N N . LYS A 1 63 ? -22.195 30.407 11.424 1.00 19.87 ? 96 LYS A N 1 ATOM 478 C CA . LYS A 1 63 ? -22.873 31.506 10.721 1.00 21.08 ? 96 LYS A CA 1 ATOM 479 C C . LYS A 1 63 ? -24.155 31.933 11.340 1.00 20.12 ? 96 LYS A C 1 ATOM 480 O O . LYS A 1 63 ? -24.466 33.069 11.312 1.00 21.59 ? 96 LYS A O 1 ATOM 481 C CB . LYS A 1 63 ? -23.279 31.068 9.346 1.00 24.18 ? 96 LYS A CB 1 ATOM 482 C CG . LYS A 1 63 ? -22.467 31.584 8.210 1.00 27.62 ? 96 LYS A CG 1 ATOM 483 C CD . LYS A 1 63 ? -23.402 31.446 7.009 1.00 34.35 ? 96 LYS A CD 1 ATOM 484 C CE . LYS A 1 63 ? -22.673 31.380 5.673 1.00 41.97 ? 96 LYS A CE 1 ATOM 485 N NZ . LYS A 1 63 ? -21.618 32.438 5.604 1.00 46.25 1 96 LYS A NZ 1 ATOM 486 N N . ASN A 1 64 ? -24.944 30.998 11.824 1.00 21.07 ? 97 ASN A N 1 ATOM 487 C CA . ASN A 1 64 ? -26.259 31.299 12.363 1.00 21.31 ? 97 ASN A CA 1 ATOM 488 C C . ASN A 1 64 ? -26.357 31.208 13.874 1.00 20.30 ? 97 ASN A C 1 ATOM 489 O O . ASN A 1 64 ? -27.438 31.201 14.400 1.00 22.35 ? 97 ASN A O 1 ATOM 490 C CB . ASN A 1 64 ? -27.293 30.333 11.733 1.00 23.24 ? 97 ASN A CB 1 ATOM 491 C CG . ASN A 1 64 ? -27.463 30.567 10.256 1.00 24.60 ? 97 ASN A CG 1 ATOM 492 O OD1 . ASN A 1 64 ? -28.303 31.323 9.851 1.00 28.57 ? 97 ASN A OD1 1 ATOM 493 N ND2 . ASN A 1 64 ? -26.607 29.989 9.460 1.00 27.45 ? 97 ASN A ND2 1 ATOM 494 N N . SER A 1 65 ? -25.248 31.106 14.599 1.00 19.53 ? 98 SER A N 1 ATOM 495 C CA . SER A 1 65 ? -25.315 30.958 16.070 1.00 17.66 ? 98 SER A CA 1 ATOM 496 C C . SER A 1 65 ? -25.653 32.271 16.725 1.00 18.09 ? 98 SER A C 1 ATOM 497 O O . SER A 1 65 ? -25.827 32.368 17.917 1.00 18.40 ? 98 SER A O 1 ATOM 498 C CB . SER A 1 65 ? -23.953 30.577 16.599 1.00 16.55 ? 98 SER A CB 1 ATOM 499 O OG . SER A 1 65 ? -23.021 31.578 16.236 1.00 14.94 ? 98 SER A OG 1 ATOM 500 N N . GLY A 1 66 ? -25.629 33.312 15.935 1.00 19.34 ? 99 GLY A N 1 ATOM 501 C CA . GLY A 1 66 ? -25.716 34.613 16.467 1.00 20.38 ? 99 GLY A CA 1 ATOM 502 C C . GLY A 1 66 ? -24.601 34.866 17.441 1.00 20.32 ? 99 GLY A C 1 ATOM 503 O O . GLY A 1 66 ? -24.873 35.394 18.489 1.00 24.45 ? 99 GLY A O 1 ATOM 504 N N . GLN A 1 67 ? -23.373 34.481 17.105 1.00 18.05 ? 100 GLN A N 1 ATOM 505 C CA . GLN A 1 67 ? -22.218 34.886 17.860 1.00 16.87 ? 100 GLN A CA 1 ATOM 506 C C . GLN A 1 67 ? -21.257 35.612 16.935 1.00 17.96 ? 100 GLN A C 1 ATOM 507 O O . GLN A 1 67 ? -20.944 35.176 15.849 1.00 17.52 ? 100 GLN A O 1 ATOM 508 C CB . GLN A 1 67 ? -21.549 33.694 18.451 1.00 16.03 ? 100 GLN A CB 1 ATOM 509 C CG . GLN A 1 67 ? -22.378 33.018 19.525 1.00 16.53 ? 100 GLN A CG 1 ATOM 510 C CD . GLN A 1 67 ? -22.194 33.624 20.888 1.00 16.00 ? 100 GLN A CD 1 ATOM 511 O OE1 . GLN A 1 67 ? -21.774 34.744 21.009 1.00 17.47 ? 100 GLN A OE1 1 ATOM 512 N NE2 . GLN A 1 67 ? -22.468 32.866 21.920 1.00 16.11 ? 100 GLN A NE2 1 ATOM 513 N N . GLU A 1 68 ? -20.798 36.749 17.394 1.00 19.85 ? 101 GLU A N 1 ATOM 514 C CA . GLU A 1 68 ? -19.966 37.637 16.652 1.00 20.81 ? 101 GLU A CA 1 ATOM 515 C C . GLU A 1 68 ? -18.548 37.156 16.948 1.00 18.89 ? 101 GLU A C 1 ATOM 516 O O . GLU A 1 68 ? -18.296 36.756 18.078 1.00 20.97 ? 101 GLU A O 1 ATOM 517 C CB . GLU A 1 68 ? -20.280 39.064 17.163 1.00 25.99 ? 101 GLU A CB 1 ATOM 518 C CG . GLU A 1 68 ? -19.807 39.456 18.624 1.00 32.90 ? 101 GLU A CG 1 ATOM 519 C CD . GLU A 1 68 ? -20.756 39.129 19.850 1.00 37.03 ? 101 GLU A CD 1 ATOM 520 O OE1 . GLU A 1 68 ? -21.731 38.316 19.745 1.00 31.02 ? 101 GLU A OE1 1 ATOM 521 O OE2 . GLU A 1 68 ? -20.487 39.687 20.981 1.00 41.51 -1 101 GLU A OE2 1 ATOM 522 N N . ALA A 1 69 ? -17.643 37.100 15.974 1.00 15.93 ? 102 ALA A N 1 ATOM 523 C CA . ALA A 1 69 ? -16.229 36.789 16.270 1.00 14.65 ? 102 ALA A CA 1 ATOM 524 C C . ALA A 1 69 ? -15.245 37.609 15.494 1.00 14.28 ? 102 ALA A C 1 ATOM 525 O O . ALA A 1 69 ? -15.485 37.918 14.348 1.00 14.31 ? 102 ALA A O 1 ATOM 526 C CB . ALA A 1 69 ? -15.915 35.320 16.024 1.00 14.32 ? 102 ALA A CB 1 ATOM 527 N N . SER A 1 70 ? -14.093 37.872 16.099 1.00 13.67 ? 103 SER A N 1 ATOM 528 C CA . SER A 1 70 ? -13.007 38.575 15.442 1.00 14.17 ? 103 SER A CA 1 ATOM 529 C C . SER A 1 70 ? -12.004 37.739 14.647 1.00 12.90 ? 103 SER A C 1 ATOM 530 O O . SER A 1 70 ? -11.238 38.264 13.838 1.00 12.70 ? 103 SER A O 1 ATOM 531 C CB . SER A 1 70 ? -12.245 39.309 16.527 1.00 15.98 ? 103 SER A CB 1 ATOM 532 O OG . SER A 1 70 ? -13.219 40.100 17.201 1.00 20.04 ? 103 SER A OG 1 ATOM 533 N N . PHE A 1 71 ? -11.933 36.458 14.936 1.00 11.71 ? 104 PHE A N 1 ATOM 534 C CA . PHE A 1 71 ? -11.134 35.562 14.139 1.00 11.18 ? 104 PHE A CA 1 ATOM 535 C C . PHE A 1 71 ? -11.438 34.109 14.468 1.00 10.23 ? 104 PHE A C 1 ATOM 536 O O . PHE A 1 71 ? -12.334 33.807 15.266 1.00 9.74 ? 104 PHE A O 1 ATOM 537 C CB . PHE A 1 71 ? -9.625 35.873 14.274 1.00 11.35 ? 104 PHE A CB 1 ATOM 538 C CG . PHE A 1 71 ? -9.090 35.687 15.654 1.00 11.48 ? 104 PHE A CG 1 ATOM 539 C CD1 . PHE A 1 71 ? -9.166 36.702 16.586 1.00 11.06 ? 104 PHE A CD1 1 ATOM 540 C CD2 . PHE A 1 71 ? -8.523 34.493 16.026 1.00 11.38 ? 104 PHE A CD2 1 ATOM 541 C CE1 . PHE A 1 71 ? -8.640 36.540 17.850 1.00 10.99 ? 104 PHE A CE1 1 ATOM 542 C CE2 . PHE A 1 71 ? -8.044 34.315 17.318 1.00 11.50 ? 104 PHE A CE2 1 ATOM 543 C CZ . PHE A 1 71 ? -8.082 35.342 18.219 1.00 11.11 ? 104 PHE A CZ 1 ATOM 544 N N . MET A 1 72 ? -10.734 33.218 13.796 1.00 9.84 ? 105 MET A N 1 ATOM 545 C CA . MET A 1 72 ? -10.948 31.794 13.982 1.00 10.56 ? 105 MET A CA 1 ATOM 546 C C . MET A 1 72 ? -9.630 31.103 13.939 1.00 8.99 ? 105 MET A C 1 ATOM 547 O O . MET A 1 72 ? -8.794 31.459 13.145 1.00 8.56 ? 105 MET A O 1 ATOM 548 C CB . MET A 1 72 ? -11.877 31.221 12.901 1.00 12.14 ? 105 MET A CB 1 ATOM 549 C CG . MET A 1 72 ? -12.026 29.693 12.908 1.00 13.77 ? 105 MET A CG 1 ATOM 550 S SD . MET A 1 72 ? -13.066 28.987 11.585 1.00 15.59 ? 105 MET A SD 1 ATOM 551 C CE . MET A 1 72 ? -14.655 29.255 12.288 1.00 16.31 ? 105 MET A CE 1 ATOM 552 N N . ILE A 1 73 ? -9.464 30.153 14.842 1.00 8.10 ? 106 ILE A N 1 ATOM 553 C CA A ILE A 1 73 ? -8.324 29.256 14.916 0.50 8.11 ? 106 ILE A CA 1 ATOM 554 C CA B ILE A 1 73 ? -8.292 29.290 14.781 0.50 7.82 ? 106 ILE A CA 1 ATOM 555 C C . ILE A 1 73 ? -8.694 27.901 14.294 1.00 7.78 ? 106 ILE A C 1 ATOM 556 O O . ILE A 1 73 ? -9.725 27.391 14.607 1.00 7.34 ? 106 ILE A O 1 ATOM 557 C CB A ILE A 1 73 ? -7.987 29.042 16.400 0.50 8.23 ? 106 ILE A CB 1 ATOM 558 C CB B ILE A 1 73 ? -7.454 29.227 16.079 0.50 7.53 ? 106 ILE A CB 1 ATOM 559 C CG1 A ILE A 1 73 ? -7.520 30.332 17.002 0.50 8.30 ? 106 ILE A CG1 1 ATOM 560 C CG1 B ILE A 1 73 ? -8.250 28.757 17.292 0.50 7.36 ? 106 ILE A CG1 1 ATOM 561 C CG2 A ILE A 1 73 ? -6.848 28.087 16.580 0.50 8.37 ? 106 ILE A CG2 1 ATOM 562 C CG2 B ILE A 1 73 ? -6.849 30.568 16.380 0.50 7.57 ? 106 ILE A CG2 1 ATOM 563 C CD1 A ILE A 1 73 ? -6.484 30.960 16.118 0.50 8.36 ? 106 ILE A CD1 1 ATOM 564 C CD1 B ILE A 1 73 ? -7.335 28.425 18.447 0.50 7.17 ? 106 ILE A CD1 1 ATOM 565 N N . TRP A 1 74 ? -7.829 27.314 13.475 1.00 7.96 ? 107 TRP A N 1 ATOM 566 C CA . TRP A 1 74 ? -8.154 26.089 12.753 1.00 8.45 ? 107 TRP A CA 1 ATOM 567 C C . TRP A 1 74 ? -6.957 25.183 12.773 1.00 8.11 ? 107 TRP A C 1 ATOM 568 O O . TRP A 1 74 ? -6.050 25.357 11.997 1.00 8.46 ? 107 TRP A O 1 ATOM 569 C CB . TRP A 1 74 ? -8.550 26.447 11.328 1.00 8.82 ? 107 TRP A CB 1 ATOM 570 C CG . TRP A 1 74 ? -8.707 25.328 10.378 1.00 9.78 ? 107 TRP A CG 1 ATOM 571 C CD1 . TRP A 1 74 ? -9.133 24.070 10.662 1.00 10.33 ? 107 TRP A CD1 1 ATOM 572 C CD2 . TRP A 1 74 ? -8.522 25.369 8.948 1.00 10.09 ? 107 TRP A CD2 1 ATOM 573 N NE1 . TRP A 1 74 ? -9.199 23.325 9.501 1.00 10.38 ? 107 TRP A NE1 1 ATOM 574 C CE2 . TRP A 1 74 ? -8.808 24.104 8.450 1.00 10.21 ? 107 TRP A CE2 1 ATOM 575 C CE3 . TRP A 1 74 ? -8.144 26.362 8.053 1.00 10.71 ? 107 TRP A CE3 1 ATOM 576 C CZ2 . TRP A 1 74 ? -8.717 23.797 7.102 1.00 10.77 ? 107 TRP A CZ2 1 ATOM 577 C CZ3 . TRP A 1 74 ? -8.024 26.048 6.696 1.00 10.63 ? 107 TRP A CZ3 1 ATOM 578 C CH2 . TRP A 1 74 ? -8.301 24.780 6.247 1.00 10.97 ? 107 TRP A CH2 1 ATOM 579 N N . THR A 1 75 ? -6.944 24.215 13.678 1.00 7.67 ? 108 THR A N 1 ATOM 580 C CA . THR A 1 75 ? -5.706 23.504 13.975 1.00 7.39 ? 108 THR A CA 1 ATOM 581 C C . THR A 1 75 ? -5.519 22.159 13.212 1.00 7.22 ? 108 THR A C 1 ATOM 582 O O . THR A 1 75 ? -4.927 21.208 13.715 1.00 7.42 ? 108 THR A O 1 ATOM 583 C CB . THR A 1 75 ? -5.458 23.423 15.510 1.00 7.13 ? 108 THR A CB 1 ATOM 584 O OG1 . THR A 1 75 ? -6.624 23.004 16.193 1.00 7.28 ? 108 THR A OG1 1 ATOM 585 C CG2 . THR A 1 75 ? -5.177 24.799 16.054 1.00 7.24 ? 108 THR A CG2 1 ATOM 586 N N . GLY A 1 76 ? -5.985 22.118 11.984 1.00 6.78 ? 109 GLY A N 1 ATOM 587 C CA . GLY A 1 76 ? -5.537 21.107 11.050 1.00 6.83 ? 109 GLY A CA 1 ATOM 588 C C . GLY A 1 76 ? -6.281 19.791 10.992 1.00 6.71 ? 109 GLY A C 1 ATOM 589 O O . GLY A 1 76 ? -7.385 19.678 11.507 1.00 6.81 ? 109 GLY A O 1 ATOM 590 N N . ASP A 1 77 ? -5.625 18.796 10.367 1.00 6.46 ? 110 ASP A N 1 ATOM 591 C CA . ASP A 1 77 ? -6.156 17.441 10.073 1.00 6.09 ? 110 ASP A CA 1 ATOM 592 C C . ASP A 1 77 ? -7.422 17.446 9.182 1.00 5.90 ? 110 ASP A C 1 ATOM 593 O O . ASP A 1 77 ? -8.531 17.200 9.647 1.00 5.70 ? 110 ASP A O 1 ATOM 594 C CB . ASP A 1 77 ? -6.415 16.687 11.381 1.00 6.22 ? 110 ASP A CB 1 ATOM 595 C CG . ASP A 1 77 ? -5.284 15.775 11.788 1.00 6.27 ? 110 ASP A CG 1 ATOM 596 O OD1 . ASP A 1 77 ? -4.156 15.912 11.251 1.00 6.34 ? 110 ASP A OD1 1 ATOM 597 O OD2 . ASP A 1 77 ? -5.531 14.945 12.706 1.00 6.44 -1 110 ASP A OD2 1 ATOM 598 N N . SER A 1 78 ? -7.253 17.716 7.895 1.00 5.76 ? 111 SER A N 1 ATOM 599 C CA . SER A 1 78 ? -8.400 17.755 6.969 1.00 5.79 ? 111 SER A CA 1 ATOM 600 C C . SER A 1 78 ? -8.673 16.463 6.192 1.00 5.95 ? 111 SER A C 1 ATOM 601 O O . SER A 1 78 ? -9.845 16.083 6.066 1.00 5.96 ? 111 SER A O 1 ATOM 602 C CB . SER A 1 78 ? -8.303 18.966 6.044 1.00 5.73 ? 111 SER A CB 1 ATOM 603 O OG . SER A 1 78 ? -8.261 20.172 6.818 1.00 5.73 ? 111 SER A OG 1 ATOM 604 N N . PRO A 1 79 ? -7.633 15.744 5.732 1.00 6.09 ? 112 PRO A N 1 ATOM 605 C CA . PRO A 1 79 ? -7.880 14.475 5.050 1.00 6.42 ? 112 PRO A CA 1 ATOM 606 C C . PRO A 1 79 ? -8.338 13.409 6.024 1.00 6.95 ? 112 PRO A C 1 ATOM 607 O O . PRO A 1 79 ? -8.085 13.535 7.173 1.00 7.03 ? 112 PRO A O 1 ATOM 608 C CB . PRO A 1 79 ? -6.491 14.067 4.527 1.00 6.32 ? 112 PRO A CB 1 ATOM 609 C CG . PRO A 1 79 ? -5.671 15.308 4.555 1.00 6.15 ? 112 PRO A CG 1 ATOM 610 C CD . PRO A 1 79 ? -6.205 16.080 5.727 1.00 6.19 ? 112 PRO A CD 1 ATOM 611 N N . PRO A 1 80 ? -8.957 12.328 5.544 1.00 7.56 ? 113 PRO A N 1 ATOM 612 C CA . PRO A 1 80 ? -9.505 11.251 6.358 1.00 7.69 ? 113 PRO A CA 1 ATOM 613 C C . PRO A 1 80 ? -8.521 10.190 6.755 1.00 8.47 ? 113 PRO A C 1 ATOM 614 O O . PRO A 1 80 ? -7.400 10.078 6.183 1.00 8.94 ? 113 PRO A O 1 ATOM 615 C CB . PRO A 1 80 ? -10.481 10.575 5.400 1.00 7.71 ? 113 PRO A CB 1 ATOM 616 C CG . PRO A 1 80 ? -9.871 10.769 4.052 1.00 7.68 ? 113 PRO A CG 1 ATOM 617 C CD . PRO A 1 80 ? -9.186 12.112 4.095 1.00 7.63 ? 113 PRO A CD 1 ATOM 618 N N . HIS A 1 81 ? -8.953 9.338 7.668 1.00 8.55 ? 114 HIS A N 1 ATOM 619 C CA . HIS A 1 81 ? -8.108 8.249 8.092 1.00 8.77 ? 114 HIS A CA 1 ATOM 620 C C . HIS A 1 81 ? -8.304 7.086 7.138 1.00 9.94 ? 114 HIS A C 1 ATOM 621 O O . HIS A 1 81 ? -9.116 6.162 7.402 1.00 9.90 ? 114 HIS A O 1 ATOM 622 C CB . HIS A 1 81 ? -8.504 7.802 9.485 1.00 8.25 ? 114 HIS A CB 1 ATOM 623 C CG . HIS A 1 81 ? -8.376 8.863 10.504 1.00 7.94 ? 114 HIS A CG 1 ATOM 624 N ND1 . HIS A 1 81 ? -9.218 9.953 10.543 1.00 7.94 ? 114 HIS A ND1 1 ATOM 625 C CD2 . HIS A 1 81 ? -7.530 8.999 11.544 1.00 7.71 ? 114 HIS A CD2 1 ATOM 626 C CE1 . HIS A 1 81 ? -8.864 10.743 11.538 1.00 7.74 ? 114 HIS A CE1 1 ATOM 627 N NE2 . HIS A 1 81 ? -7.860 10.173 12.177 1.00 7.90 ? 114 HIS A NE2 1 ATOM 628 N N . VAL A 1 82 ? -7.570 7.110 6.033 1.00 10.95 ? 115 VAL A N 1 ATOM 629 C CA . VAL A 1 82 ? -7.544 5.941 5.142 1.00 11.80 ? 115 VAL A CA 1 ATOM 630 C C . VAL A 1 82 ? -6.109 5.485 5.107 1.00 12.24 ? 115 VAL A C 1 ATOM 631 O O . VAL A 1 82 ? -5.239 6.220 5.467 1.00 12.34 ? 115 VAL A O 1 ATOM 632 C CB . VAL A 1 82 ? -8.024 6.261 3.754 1.00 12.03 ? 115 VAL A CB 1 ATOM 633 C CG1 . VAL A 1 82 ? -9.505 6.582 3.728 1.00 12.13 ? 115 VAL A CG1 1 ATOM 634 C CG2 . VAL A 1 82 ? -7.278 7.464 3.256 1.00 12.71 ? 115 VAL A CG2 1 ATOM 635 N N . PRO A 1 83 ? -5.856 4.256 4.690 1.00 13.05 ? 116 PRO A N 1 ATOM 636 C CA . PRO A 1 83 ? -4.468 3.848 4.609 1.00 12.92 ? 116 PRO A CA 1 ATOM 637 C C . PRO A 1 83 ? -3.696 4.706 3.623 1.00 13.06 ? 116 PRO A C 1 ATOM 638 O O . PRO A 1 83 ? -4.241 5.128 2.599 1.00 13.49 ? 116 PRO A O 1 ATOM 639 C CB . PRO A 1 83 ? -4.549 2.392 4.152 1.00 13.07 ? 116 PRO A CB 1 ATOM 640 C CG . PRO A 1 83 ? -5.950 1.963 4.381 1.00 13.21 ? 116 PRO A CG 1 ATOM 641 C CD . PRO A 1 83 ? -6.788 3.197 4.285 1.00 13.40 ? 116 PRO A CD 1 ATOM 642 N N . VAL A 1 84 ? -2.452 4.972 3.961 1.00 13.38 ? 117 VAL A N 1 ATOM 643 C CA . VAL A 1 84 ? -1.565 5.813 3.178 1.00 15.66 ? 117 VAL A CA 1 ATOM 644 C C . VAL A 1 84 ? -1.595 5.613 1.639 1.00 18.21 ? 117 VAL A C 1 ATOM 645 O O . VAL A 1 84 ? -1.723 6.600 0.917 1.00 20.95 ? 117 VAL A O 1 ATOM 646 C CB . VAL A 1 84 ? -0.117 5.708 3.698 1.00 16.56 ? 117 VAL A CB 1 ATOM 647 C CG1 . VAL A 1 84 ? 0.824 6.513 2.829 1.00 17.84 ? 117 VAL A CG1 1 ATOM 648 C CG2 . VAL A 1 84 ? -0.013 6.235 5.129 1.00 16.35 ? 117 VAL A CG2 1 ATOM 649 N N . PRO A 1 85 ? -1.536 4.358 1.124 1.00 20.33 ? 118 PRO A N 1 ATOM 650 C CA . PRO A 1 85 ? -1.584 4.156 -0.350 1.00 21.25 ? 118 PRO A CA 1 ATOM 651 C C . PRO A 1 85 ? -2.858 4.594 -1.050 1.00 23.27 ? 118 PRO A C 1 ATOM 652 O O . PRO A 1 85 ? -2.888 4.770 -2.269 1.00 23.08 ? 118 PRO A O 1 ATOM 653 C CB . PRO A 1 85 ? -1.401 2.644 -0.519 1.00 20.48 ? 118 PRO A CB 1 ATOM 654 C CG . PRO A 1 85 ? -0.722 2.207 0.731 1.00 21.44 ? 118 PRO A CG 1 ATOM 655 C CD . PRO A 1 85 ? -1.271 3.087 1.825 1.00 20.49 ? 118 PRO A CD 1 ATOM 656 N N . GLU A 1 86 ? -3.914 4.765 -0.291 1.00 24.94 ? 119 GLU A N 1 ATOM 657 C CA . GLU A 1 86 ? -5.188 5.166 -0.877 1.00 26.11 ? 119 GLU A CA 1 ATOM 658 C C . GLU A 1 86 ? -5.179 6.686 -1.072 1.00 22.81 ? 119 GLU A C 1 ATOM 659 O O . GLU A 1 86 ? -6.011 7.217 -1.743 1.00 22.82 ? 119 GLU A O 1 ATOM 660 C CB . GLU A 1 86 ? -6.332 4.725 0.069 1.00 29.25 ? 119 GLU A CB 1 ATOM 661 C CG . GLU A 1 86 ? -7.392 3.890 -0.593 1.00 35.87 ? 119 GLU A CG 1 ATOM 662 C CD . GLU A 1 86 ? -8.620 3.626 0.300 1.00 42.59 ? 119 GLU A CD 1 ATOM 663 O OE1 . GLU A 1 86 ? -9.688 4.297 0.099 1.00 45.03 ? 119 GLU A OE1 1 ATOM 664 O OE2 . GLU A 1 86 ? -8.521 2.730 1.173 1.00 38.85 -1 119 GLU A OE2 1 ATOM 665 N N . LEU A 1 87 ? -4.246 7.385 -0.447 1.00 21.09 ? 120 LEU A N 1 ATOM 666 C CA . LEU A 1 87 ? -4.153 8.838 -0.563 1.00 21.31 ? 120 LEU A CA 1 ATOM 667 C C . LEU A 1 87 ? -2.926 9.251 -1.374 1.00 19.78 ? 120 LEU A C 1 ATOM 668 O O . LEU A 1 87 ? -2.147 8.439 -1.720 1.00 21.94 ? 120 LEU A O 1 ATOM 669 C CB . LEU A 1 87 ? -4.078 9.501 0.848 1.00 21.03 ? 120 LEU A CB 1 ATOM 670 C CG . LEU A 1 87 ? -5.366 9.553 1.675 1.00 20.49 ? 120 LEU A CG 1 ATOM 671 C CD1 . LEU A 1 87 ? -5.153 10.201 3.029 1.00 19.88 ? 120 LEU A CD1 1 ATOM 672 C CD2 . LEU A 1 87 ? -6.486 10.256 0.938 1.00 21.26 ? 120 LEU A CD2 1 ATOM 673 N N . SER A 1 88 ? -2.752 10.530 -1.621 1.00 18.31 ? 121 SER A N 1 ATOM 674 C CA . SER A 1 88 ? -1.585 11.029 -2.262 1.00 17.71 ? 121 SER A CA 1 ATOM 675 C C . SER A 1 88 ? -1.421 12.542 -1.960 1.00 17.74 ? 121 SER A C 1 ATOM 676 O O . SER A 1 88 ? -2.340 13.186 -1.454 1.00 17.79 ? 121 SER A O 1 ATOM 677 C CB . SER A 1 88 ? -1.760 10.844 -3.749 1.00 16.46 ? 121 SER A CB 1 ATOM 678 O OG . SER A 1 88 ? -2.667 11.838 -4.182 1.00 17.29 ? 121 SER A OG 1 ATOM 679 N N . THR A 1 89 ? -0.263 13.099 -2.310 1.00 16.91 ? 122 THR A N 1 ATOM 680 C CA . THR A 1 89 ? -0.011 14.525 -2.202 1.00 16.74 ? 122 THR A CA 1 ATOM 681 C C . THR A 1 89 ? -1.093 15.326 -2.879 1.00 18.06 ? 122 THR A C 1 ATOM 682 O O . THR A 1 89 ? -1.605 16.292 -2.351 1.00 20.72 ? 122 THR A O 1 ATOM 683 C CB . THR A 1 89 ? 1.327 14.841 -2.815 1.00 16.19 ? 122 THR A CB 1 ATOM 684 O OG1 . THR A 1 89 ? 2.310 14.198 -2.021 1.00 15.81 ? 122 THR A OG1 1 ATOM 685 C CG2 . THR A 1 89 ? 1.633 16.343 -2.854 1.00 16.87 ? 122 THR A CG2 1 ATOM 686 N N . ASP A 1 90 ? -1.501 14.892 -4.034 1.00 19.62 ? 123 ASP A N 1 ATOM 687 C CA . ASP A 1 90 ? -2.459 15.669 -4.786 1.00 21.09 ? 123 ASP A CA 1 ATOM 688 C C . ASP A 1 90 ? -3.819 15.681 -4.079 1.00 19.07 ? 123 ASP A C 1 ATOM 689 O O . ASP A 1 90 ? -4.480 16.693 -4.015 1.00 19.84 ? 123 ASP A O 1 ATOM 690 C CB . ASP A 1 90 ? -2.561 15.087 -6.208 1.00 23.71 ? 123 ASP A CB 1 ATOM 691 C CG . ASP A 1 90 ? -3.599 15.779 -7.024 1.00 29.26 ? 123 ASP A CG 1 ATOM 692 O OD1 . ASP A 1 90 ? -3.477 17.018 -7.255 1.00 35.95 ? 123 ASP A OD1 1 ATOM 693 O OD2 . ASP A 1 90 ? -4.581 15.097 -7.399 1.00 32.63 -1 123 ASP A OD2 1 ATOM 694 N N . THR A 1 91 ? -4.254 14.520 -3.604 1.00 17.62 ? 124 THR A N 1 ATOM 695 C CA . THR A 1 91 ? -5.543 14.377 -2.957 1.00 16.32 ? 124 THR A CA 1 ATOM 696 C C . THR A 1 91 ? -5.568 15.062 -1.615 1.00 15.19 ? 124 THR A C 1 ATOM 697 O O . THR A 1 91 ? -6.534 15.682 -1.278 1.00 15.15 ? 124 THR A O 1 ATOM 698 C CB . THR A 1 91 ? -5.851 12.914 -2.734 1.00 16.77 ? 124 THR A CB 1 ATOM 699 O OG1 . THR A 1 91 ? -5.957 12.285 -4.012 1.00 18.33 ? 124 THR A OG1 1 ATOM 700 C CG2 . THR A 1 91 ? -7.168 12.765 -2.008 1.00 16.97 ? 124 THR A CG2 1 ATOM 701 N N . VAL A 1 92 ? -4.494 14.937 -0.845 1.00 14.18 ? 125 VAL A N 1 ATOM 702 C CA . VAL A 1 92 ? -4.366 15.691 0.384 1.00 13.31 ? 125 VAL A CA 1 ATOM 703 C C . VAL A 1 92 ? -4.528 17.180 0.143 1.00 13.09 ? 125 VAL A C 1 ATOM 704 O O . VAL A 1 92 ? -5.313 17.806 0.821 1.00 13.38 ? 125 VAL A O 1 ATOM 705 C CB . VAL A 1 92 ? -3.035 15.400 1.030 1.00 12.74 ? 125 VAL A CB 1 ATOM 706 C CG1 . VAL A 1 92 ? -2.616 16.516 1.972 1.00 12.17 ? 125 VAL A CG1 1 ATOM 707 C CG2 . VAL A 1 92 ? -3.111 14.033 1.686 1.00 12.52 ? 125 VAL A CG2 1 ATOM 708 N N . ILE A 1 93 ? -3.830 17.723 -0.853 1.00 12.91 ? 126 ILE A N 1 ATOM 709 C CA . ILE A 1 93 ? -3.944 19.138 -1.198 1.00 12.26 ? 126 ILE A CA 1 ATOM 710 C C . ILE A 1 93 ? -5.352 19.521 -1.608 1.00 13.23 ? 126 ILE A C 1 ATOM 711 O O . ILE A 1 93 ? -5.884 20.571 -1.187 1.00 12.97 ? 126 ILE A O 1 ATOM 712 C CB . ILE A 1 93 ? -2.915 19.531 -2.262 1.00 11.86 ? 126 ILE A CB 1 ATOM 713 C CG1 . ILE A 1 93 ? -1.532 19.485 -1.615 1.00 12.13 ? 126 ILE A CG1 1 ATOM 714 C CG2 . ILE A 1 93 ? -3.203 20.921 -2.779 1.00 11.73 ? 126 ILE A CG2 1 ATOM 715 C CD1 . ILE A 1 93 ? -0.357 19.592 -2.536 1.00 11.96 ? 126 ILE A CD1 1 ATOM 716 N N . ASN A 1 94 ? -6.017 18.673 -2.378 1.00 14.57 ? 127 ASN A N 1 ATOM 717 C CA . ASN A 1 94 ? -7.388 19.000 -2.700 1.00 15.90 ? 127 ASN A CA 1 ATOM 718 C C . ASN A 1 94 ? -8.297 19.046 -1.525 1.00 14.42 ? 127 ASN A C 1 ATOM 719 O O . ASN A 1 94 ? -9.248 19.832 -1.498 1.00 15.51 ? 127 ASN A O 1 ATOM 720 C CB . ASN A 1 94 ? -7.970 18.018 -3.640 1.00 19.61 ? 127 ASN A CB 1 ATOM 721 C CG . ASN A 1 94 ? -7.381 18.137 -5.028 1.00 24.52 ? 127 ASN A CG 1 ATOM 722 O OD1 . ASN A 1 94 ? -6.615 19.054 -5.334 1.00 26.99 ? 127 ASN A OD1 1 ATOM 723 N ND2 . ASN A 1 94 ? -7.719 17.179 -5.871 1.00 27.15 ? 127 ASN A ND2 1 ATOM 724 N N . VAL A 1 95 ? -8.070 18.182 -0.559 1.00 12.52 ? 128 VAL A N 1 ATOM 725 C CA . VAL A 1 95 ? -8.907 18.212 0.600 1.00 11.71 ? 128 VAL A CA 1 ATOM 726 C C . VAL A 1 95 ? -8.650 19.476 1.399 1.00 11.15 ? 128 VAL A C 1 ATOM 727 O O . VAL A 1 95 ? -9.568 20.141 1.828 1.00 9.82 ? 128 VAL A O 1 ATOM 728 C CB . VAL A 1 95 ? -8.680 16.986 1.452 1.00 11.80 ? 128 VAL A CB 1 ATOM 729 C CG1 . VAL A 1 95 ? -9.324 17.178 2.816 1.00 11.47 ? 128 VAL A CG1 1 ATOM 730 C CG2 . VAL A 1 95 ? -9.312 15.823 0.711 1.00 11.88 ? 128 VAL A CG2 1 ATOM 731 N N . ILE A 1 96 ? -7.393 19.856 1.530 1.00 10.92 ? 129 ILE A N 1 ATOM 732 C CA . ILE A 1 96 ? -7.116 21.066 2.254 1.00 10.84 ? 129 ILE A CA 1 ATOM 733 C C . ILE A 1 96 ? -7.680 22.272 1.537 1.00 11.04 ? 129 ILE A C 1 ATOM 734 O O . ILE A 1 96 ? -8.250 23.193 2.166 1.00 10.41 ? 129 ILE A O 1 ATOM 735 C CB . ILE A 1 96 ? -5.654 21.201 2.510 1.00 10.79 ? 129 ILE A CB 1 ATOM 736 C CG1 . ILE A 1 96 ? -5.206 20.004 3.325 1.00 11.10 ? 129 ILE A CG1 1 ATOM 737 C CG2 . ILE A 1 96 ? -5.387 22.497 3.262 1.00 11.13 ? 129 ILE A CG2 1 ATOM 738 C CD1 . ILE A 1 96 ? -3.730 20.025 3.669 1.00 11.45 ? 129 ILE A CD1 1 ATOM 739 N N . THR A 1 97 ? -7.538 22.249 0.209 1.00 11.75 ? 130 THR A N 1 ATOM 740 C CA . THR A 1 97 ? -8.074 23.309 -0.650 1.00 11.62 ? 130 THR A CA 1 ATOM 741 C C . THR A 1 97 ? -9.549 23.441 -0.467 1.00 11.74 ? 130 THR A C 1 ATOM 742 O O . THR A 1 97 ? -10.057 24.530 -0.285 1.00 11.87 ? 130 THR A O 1 ATOM 743 C CB . THR A 1 97 ? -7.779 23.002 -2.121 1.00 12.18 ? 130 THR A CB 1 ATOM 744 O OG1 . THR A 1 97 ? -6.356 22.981 -2.320 1.00 12.71 ? 130 THR A OG1 1 ATOM 745 C CG2 . THR A 1 97 ? -8.369 24.079 -3.020 1.00 12.02 ? 130 THR A CG2 1 ATOM 746 N N . ASN A 1 98 ? -10.240 22.307 -0.499 1.00 12.36 ? 131 ASN A N 1 ATOM 747 C CA . ASN A 1 98 ? -11.677 22.277 -0.318 1.00 13.07 ? 131 ASN A CA 1 ATOM 748 C C . ASN A 1 98 ? -12.121 22.860 1.013 1.00 12.30 ? 131 ASN A C 1 ATOM 749 O O . ASN A 1 98 ? -13.090 23.593 1.075 1.00 12.07 ? 131 ASN A O 1 ATOM 750 C CB . ASN A 1 98 ? -12.201 20.847 -0.459 1.00 14.16 ? 131 ASN A CB 1 ATOM 751 C CG . ASN A 1 98 ? -13.694 20.770 -0.290 1.00 16.53 ? 131 ASN A CG 1 ATOM 752 O OD1 . ASN A 1 98 ? -14.242 21.168 0.748 1.00 18.15 ? 131 ASN A OD1 1 ATOM 753 N ND2 . ASN A 1 98 ? -14.378 20.270 -1.311 1.00 20.96 ? 131 ASN A ND2 1 ATOM 754 N N . MET A 1 99 ? -11.453 22.477 2.092 1.00 12.46 ? 132 MET A N 1 ATOM 755 C CA . MET A 1 99 ? -11.783 23.013 3.432 1.00 12.43 ? 132 MET A CA 1 ATOM 756 C C . MET A 1 99 ? -11.530 24.528 3.451 1.00 12.20 ? 132 MET A C 1 ATOM 757 O O . MET A 1 99 ? -12.383 25.316 3.899 1.00 10.97 ? 132 MET A O 1 ATOM 758 C CB . MET A 1 99 ? -10.976 22.320 4.541 1.00 12.10 ? 132 MET A CB 1 ATOM 759 C CG . MET A 1 99 ? -11.326 20.863 4.793 1.00 11.88 ? 132 MET A CG 1 ATOM 760 S SD . MET A 1 99 ? -12.974 20.662 5.405 1.00 12.30 ? 132 MET A SD 1 ATOM 761 C CE . MET A 1 99 ? -13.831 20.421 3.860 1.00 13.31 ? 132 MET A CE 1 ATOM 762 N N . THR A 1 100 ? -10.365 24.915 2.950 1.00 12.63 ? 133 THR A N 1 ATOM 763 C CA . THR A 1 100 ? -10.016 26.330 2.893 1.00 13.94 ? 133 THR A CA 1 ATOM 764 C C . THR A 1 100 ? -11.007 27.158 2.094 1.00 14.35 ? 133 THR A C 1 ATOM 765 O O . THR A 1 100 ? -11.539 28.161 2.546 1.00 14.67 ? 133 THR A O 1 ATOM 766 C CB . THR A 1 100 ? -8.616 26.514 2.293 1.00 14.06 ? 133 THR A CB 1 ATOM 767 O OG1 . THR A 1 100 ? -7.662 25.865 3.139 1.00 13.00 ? 133 THR A OG1 1 ATOM 768 C CG2 . THR A 1 100 ? -8.250 28.057 2.157 1.00 14.62 ? 133 THR A CG2 1 ATOM 769 N N . THR A 1 101 ? -11.269 26.700 0.905 1.00 15.55 ? 134 THR A N 1 ATOM 770 C CA . THR A 1 101 ? -12.252 27.329 0.041 1.00 16.73 ? 134 THR A CA 1 ATOM 771 C C . THR A 1 101 ? -13.617 27.381 0.679 1.00 15.40 ? 134 THR A C 1 ATOM 772 O O . THR A 1 101 ? -14.285 28.384 0.633 1.00 15.59 ? 134 THR A O 1 ATOM 773 C CB . THR A 1 101 ? -12.321 26.530 -1.280 1.00 18.62 ? 134 THR A CB 1 ATOM 774 O OG1 . THR A 1 101 ? -11.066 26.679 -1.953 1.00 19.03 ? 134 THR A OG1 1 ATOM 775 C CG2 . THR A 1 101 ? -13.414 27.074 -2.173 1.00 21.02 ? 134 THR A CG2 1 ATOM 776 N N . THR A 1 102 ? -14.052 26.274 1.244 1.00 14.56 ? 135 THR A N 1 ATOM 777 C CA . THR A 1 102 ? -15.311 26.266 1.943 1.00 14.56 ? 135 THR A CA 1 ATOM 778 C C . THR A 1 102 ? -15.377 27.328 3.070 1.00 15.16 ? 135 THR A C 1 ATOM 779 O O . THR A 1 102 ? -16.350 28.048 3.182 1.00 17.77 ? 135 THR A O 1 ATOM 780 C CB . THR A 1 102 ? -15.557 24.884 2.523 1.00 14.83 ? 135 THR A CB 1 ATOM 781 O OG1 . THR A 1 102 ? -15.579 23.911 1.474 1.00 14.45 ? 135 THR A OG1 1 ATOM 782 C CG2 . THR A 1 102 ? -16.836 24.858 3.271 1.00 15.08 ? 135 THR A CG2 1 ATOM 783 N N . ILE A 1 103 ? -14.344 27.450 3.891 1.00 14.43 ? 136 ILE A N 1 ATOM 784 C CA . ILE A 1 103 ? -14.313 28.492 4.925 1.00 14.45 ? 136 ILE A CA 1 ATOM 785 C C . ILE A 1 103 ? -14.266 29.914 4.348 1.00 14.26 ? 136 ILE A C 1 ATOM 786 O O . ILE A 1 103 ? -14.927 30.816 4.834 1.00 13.01 ? 136 ILE A O 1 ATOM 787 C CB . ILE A 1 103 ? -13.093 28.287 5.865 1.00 14.60 ? 136 ILE A CB 1 ATOM 788 C CG1 . ILE A 1 103 ? -13.265 27.018 6.690 1.00 14.33 ? 136 ILE A CG1 1 ATOM 789 C CG2 . ILE A 1 103 ? -12.863 29.481 6.784 1.00 14.62 ? 136 ILE A CG2 1 ATOM 790 C CD1 . ILE A 1 103 ? -11.970 26.549 7.286 1.00 14.56 ? 136 ILE A CD1 1 ATOM 791 N N . GLN A 1 104 ? -13.467 30.109 3.305 1.00 15.22 ? 137 GLN A N 1 ATOM 792 C CA . GLN A 1 104 ? -13.329 31.446 2.698 1.00 15.09 ? 137 GLN A CA 1 ATOM 793 C C . GLN A 1 104 ? -14.604 31.943 2.065 1.00 14.80 ? 137 GLN A C 1 ATOM 794 O O . GLN A 1 104 ? -14.914 33.100 2.172 1.00 14.81 ? 137 GLN A O 1 ATOM 795 C CB . GLN A 1 104 ? -12.184 31.470 1.718 1.00 15.25 ? 137 GLN A CB 1 ATOM 796 C CG . GLN A 1 104 ? -10.861 31.713 2.421 1.00 15.62 ? 137 GLN A CG 1 ATOM 797 C CD . GLN A 1 104 ? -9.683 31.330 1.582 1.00 16.56 ? 137 GLN A CD 1 ATOM 798 O OE1 . GLN A 1 104 ? -9.848 30.988 0.437 1.00 17.93 ? 137 GLN A OE1 1 ATOM 799 N NE2 . GLN A 1 104 ? -8.485 31.341 2.159 1.00 17.66 ? 137 GLN A NE2 1 ATOM 800 N N . SER A 1 105 ? -15.360 31.063 1.435 1.00 15.79 ? 138 SER A N 1 ATOM 801 C CA . SER A 1 105 ? -16.714 31.402 0.952 1.00 16.95 ? 138 SER A CA 1 ATOM 802 C C . SER A 1 105 ? -17.711 31.758 1.970 1.00 17.45 ? 138 SER A C 1 ATOM 803 O O . SER A 1 105 ? -18.551 32.554 1.687 1.00 18.39 ? 138 SER A O 1 ATOM 804 C CB . SER A 1 105 ? -17.396 30.209 0.288 1.00 17.30 ? 138 SER A CB 1 ATOM 805 O OG . SER A 1 105 ? -16.577 29.778 -0.727 1.00 19.28 ? 138 SER A OG 1 ATOM 806 N N . LEU A 1 106 ? -17.746 31.034 3.083 1.00 19.14 ? 139 LEU A N 1 ATOM 807 C CA . LEU A 1 106 ? -18.804 31.254 4.033 1.00 18.77 ? 139 LEU A CA 1 ATOM 808 C C . LEU A 1 106 ? -18.438 32.384 4.949 1.00 17.74 ? 139 LEU A C 1 ATOM 809 O O . LEU A 1 106 ? -19.318 32.932 5.553 1.00 17.37 ? 139 LEU A O 1 ATOM 810 C CB . LEU A 1 106 ? -19.096 30.012 4.845 1.00 20.41 ? 139 LEU A CB 1 ATOM 811 C CG . LEU A 1 106 ? -19.625 28.771 4.113 1.00 22.54 ? 139 LEU A CG 1 ATOM 812 C CD1 . LEU A 1 106 ? -19.799 27.664 5.139 1.00 23.68 ? 139 LEU A CD1 1 ATOM 813 C CD2 . LEU A 1 106 ? -20.962 28.950 3.424 1.00 22.26 ? 139 LEU A CD2 1 ATOM 814 N N . PHE A 1 107 ? -17.153 32.708 5.094 1.00 16.43 ? 140 PHE A N 1 ATOM 815 C CA . PHE A 1 107 ? -16.715 33.741 6.054 1.00 16.03 ? 140 PHE A CA 1 ATOM 816 C C . PHE A 1 107 ? -15.785 34.696 5.315 1.00 17.02 ? 140 PHE A C 1 ATOM 817 O O . PHE A 1 107 ? -14.588 34.802 5.604 1.00 16.55 ? 140 PHE A O 1 ATOM 818 C CB . PHE A 1 107 ? -16.007 33.113 7.271 1.00 15.36 ? 140 PHE A CB 1 ATOM 819 C CG . PHE A 1 107 ? -16.836 32.097 7.980 1.00 15.16 ? 140 PHE A CG 1 ATOM 820 C CD1 . PHE A 1 107 ? -17.922 32.497 8.761 1.00 14.53 ? 140 PHE A CD1 1 ATOM 821 C CD2 . PHE A 1 107 ? -16.586 30.742 7.819 1.00 14.25 ? 140 PHE A CD2 1 ATOM 822 C CE1 . PHE A 1 107 ? -18.708 31.570 9.404 1.00 14.09 ? 140 PHE A CE1 1 ATOM 823 C CE2 . PHE A 1 107 ? -17.388 29.819 8.433 1.00 14.13 ? 140 PHE A CE2 1 ATOM 824 C CZ . PHE A 1 107 ? -18.437 30.231 9.246 1.00 14.37 ? 140 PHE A CZ 1 ATOM 825 N N . PRO A 1 108 ? -16.314 35.364 4.306 1.00 19.27 ? 141 PRO A N 1 ATOM 826 C CA . PRO A 1 108 ? -15.474 36.214 3.460 1.00 21.00 ? 141 PRO A CA 1 ATOM 827 C C . PRO A 1 108 ? -14.700 37.346 4.206 1.00 22.42 ? 141 PRO A C 1 ATOM 828 O O . PRO A 1 108 ? -13.684 37.786 3.713 1.00 22.49 ? 141 PRO A O 1 ATOM 829 C CB . PRO A 1 108 ? -16.477 36.803 2.447 1.00 20.85 ? 141 PRO A CB 1 ATOM 830 C CG . PRO A 1 108 ? -17.815 36.605 3.054 1.00 20.73 ? 141 PRO A CG 1 ATOM 831 C CD . PRO A 1 108 ? -17.699 35.318 3.820 1.00 20.37 ? 141 PRO A CD 1 ATOM 832 N N . ASN A 1 109 ? -15.168 37.784 5.375 1.00 23.55 ? 142 ASN A N 1 ATOM 833 C CA . ASN A 1 109 ? -14.486 38.830 6.127 1.00 22.33 ? 142 ASN A CA 1 ATOM 834 C C . ASN A 1 109 ? -13.943 38.399 7.484 1.00 20.90 ? 142 ASN A C 1 ATOM 835 O O . ASN A 1 109 ? -13.804 39.230 8.390 1.00 21.96 ? 142 ASN A O 1 ATOM 836 C CB . ASN A 1 109 ? -15.408 40.026 6.324 1.00 22.90 ? 142 ASN A CB 1 ATOM 837 C CG . ASN A 1 109 ? -15.892 40.585 5.023 1.00 24.59 ? 142 ASN A CG 1 ATOM 838 O OD1 . ASN A 1 109 ? -17.086 40.726 4.834 1.00 27.92 ? 142 ASN A OD1 1 ATOM 839 N ND2 . ASN A 1 109 ? -14.985 40.852 4.096 1.00 27.16 ? 142 ASN A ND2 1 ATOM 840 N N . LEU A 1 110 ? -13.575 37.135 7.621 1.00 17.04 ? 143 LEU A N 1 ATOM 841 C CA . LEU A 1 110 ? -13.059 36.684 8.868 1.00 14.41 ? 143 LEU A CA 1 ATOM 842 C C . LEU A 1 110 ? -11.666 36.246 8.694 1.00 12.21 ? 143 LEU A C 1 ATOM 843 O O . LEU A 1 110 ? -11.394 35.394 7.897 1.00 12.79 ? 143 LEU A O 1 ATOM 844 C CB . LEU A 1 110 ? -13.906 35.515 9.347 1.00 14.85 ? 143 LEU A CB 1 ATOM 845 C CG . LEU A 1 110 ? -13.612 34.988 10.756 1.00 14.36 ? 143 LEU A CG 1 ATOM 846 C CD1 . LEU A 1 110 ? -14.031 35.933 11.850 1.00 14.23 ? 143 LEU A CD1 1 ATOM 847 C CD2 . LEU A 1 110 ? -14.411 33.740 10.886 1.00 14.54 ? 143 LEU A CD2 1 ATOM 848 N N . GLN A 1 111 ? -10.760 36.787 9.471 1.00 10.82 ? 144 GLN A N 1 ATOM 849 C CA . GLN A 1 111 ? -9.406 36.274 9.477 1.00 9.84 ? 144 GLN A CA 1 ATOM 850 C C . GLN A 1 111 ? -9.382 34.886 10.178 1.00 9.57 ? 144 GLN A C 1 ATOM 851 O O . GLN A 1 111 ? -10.023 34.679 11.210 1.00 9.17 ? 144 GLN A O 1 ATOM 852 C CB . GLN A 1 111 ? -8.486 37.235 10.181 1.00 9.55 ? 144 GLN A CB 1 ATOM 853 C CG . GLN A 1 111 ? -7.034 36.947 9.903 1.00 9.80 ? 144 GLN A CG 1 ATOM 854 C CD . GLN A 1 111 ? -6.151 37.952 10.570 1.00 10.55 ? 144 GLN A CD 1 ATOM 855 O OE1 . GLN A 1 111 ? -6.568 38.659 11.509 1.00 10.96 ? 144 GLN A OE1 1 ATOM 856 N NE2 . GLN A 1 111 ? -4.928 38.042 10.102 1.00 10.89 ? 144 GLN A NE2 1 ATOM 857 N N . VAL A 1 112 ? -8.658 33.941 9.592 1.00 8.91 ? 145 VAL A N 1 ATOM 858 C CA . VAL A 1 112 ? -8.596 32.615 10.104 1.00 8.30 ? 145 VAL A CA 1 ATOM 859 C C . VAL A 1 112 ? -7.132 32.238 10.213 1.00 8.01 ? 145 VAL A C 1 ATOM 860 O O . VAL A 1 112 ? -6.393 32.486 9.304 1.00 7.90 ? 145 VAL A O 1 ATOM 861 C CB . VAL A 1 112 ? -9.317 31.705 9.146 1.00 8.25 ? 145 VAL A CB 1 ATOM 862 C CG1 . VAL A 1 112 ? -9.165 30.233 9.541 1.00 8.34 ? 145 VAL A CG1 1 ATOM 863 C CG2 . VAL A 1 112 ? -10.771 32.134 9.098 1.00 8.31 ? 145 VAL A CG2 1 ATOM 864 N N . PHE A 1 113 ? -6.737 31.600 11.307 1.00 7.60 ? 146 PHE A N 1 ATOM 865 C CA . PHE A 1 113 ? -5.368 31.263 11.531 1.00 7.59 ? 146 PHE A CA 1 ATOM 866 C C . PHE A 1 113 ? -5.149 29.771 11.480 1.00 7.24 ? 146 PHE A C 1 ATOM 867 O O . PHE A 1 113 ? -5.567 29.091 12.366 1.00 7.17 ? 146 PHE A O 1 ATOM 868 C CB . PHE A 1 113 ? -4.995 31.787 12.903 1.00 7.87 ? 146 PHE A CB 1 ATOM 869 C CG . PHE A 1 113 ? -4.927 33.291 12.962 1.00 7.93 ? 146 PHE A CG 1 ATOM 870 C CD1 . PHE A 1 113 ? -6.018 34.021 13.358 1.00 7.88 ? 146 PHE A CD1 1 ATOM 871 C CD2 . PHE A 1 113 ? -3.778 33.957 12.602 1.00 7.76 ? 146 PHE A CD2 1 ATOM 872 C CE1 . PHE A 1 113 ? -5.954 35.399 13.397 1.00 8.03 ? 146 PHE A CE1 1 ATOM 873 C CE2 . PHE A 1 113 ? -3.731 35.327 12.631 1.00 7.84 ? 146 PHE A CE2 1 ATOM 874 C CZ . PHE A 1 113 ? -4.815 36.053 13.018 1.00 7.74 ? 146 PHE A CZ 1 ATOM 875 N N . PRO A 1 114 ? -4.532 29.250 10.409 1.00 7.12 ? 147 PRO A N 1 ATOM 876 C CA . PRO A 1 114 ? -4.440 27.801 10.358 1.00 6.87 ? 147 PRO A CA 1 ATOM 877 C C . PRO A 1 114 ? -3.168 27.219 10.944 1.00 6.63 ? 147 PRO A C 1 ATOM 878 O O . PRO A 1 114 ? -2.166 27.886 11.054 1.00 6.68 ? 147 PRO A O 1 ATOM 879 C CB . PRO A 1 114 ? -4.482 27.500 8.852 1.00 6.97 ? 147 PRO A CB 1 ATOM 880 C CG . PRO A 1 114 ? -5.105 28.679 8.248 1.00 7.11 ? 147 PRO A CG 1 ATOM 881 C CD . PRO A 1 114 ? -4.524 29.810 9.041 1.00 7.15 ? 147 PRO A CD 1 ATOM 882 N N . ALA A 1 115 ? -3.249 25.971 11.339 1.00 6.45 ? 148 ALA A N 1 ATOM 883 C CA . ALA A 1 115 ? -2.106 25.205 11.618 1.00 6.73 ? 148 ALA A CA 1 ATOM 884 C C . ALA A 1 115 ? -2.262 23.859 10.889 1.00 6.87 ? 148 ALA A C 1 ATOM 885 O O . ALA A 1 115 ? -3.402 23.378 10.709 1.00 7.31 ? 148 ALA A O 1 ATOM 886 C CB . ALA A 1 115 ? -2.018 24.997 13.108 1.00 6.85 ? 148 ALA A CB 1 ATOM 887 N N . LEU A 1 116 ? -1.139 23.270 10.501 1.00 6.59 ? 149 LEU A N 1 ATOM 888 C CA . LEU A 1 116 ? -1.090 21.971 9.910 1.00 6.65 ? 149 LEU A CA 1 ATOM 889 C C . LEU A 1 116 ? -1.183 20.851 10.911 1.00 6.79 ? 149 LEU A C 1 ATOM 890 O O . LEU A 1 116 ? -0.595 20.909 11.976 1.00 6.59 ? 149 LEU A O 1 ATOM 891 C CB . LEU A 1 116 ? 0.229 21.803 9.191 1.00 6.98 ? 149 LEU A CB 1 ATOM 892 C CG . LEU A 1 116 ? 0.334 22.654 7.916 1.00 7.24 ? 149 LEU A CG 1 ATOM 893 C CD1 . LEU A 1 116 ? 1.745 22.623 7.400 1.00 7.24 ? 149 LEU A CD1 1 ATOM 894 C CD2 . LEU A 1 116 ? -0.595 22.120 6.841 1.00 7.26 ? 149 LEU A CD2 1 ATOM 895 N N . GLY A 1 117 ? -1.888 19.788 10.522 1.00 7.11 ? 150 GLY A N 1 ATOM 896 C CA . GLY A 1 117 ? -2.002 18.586 11.316 1.00 7.37 ? 150 GLY A CA 1 ATOM 897 C C . GLY A 1 117 ? -1.142 17.476 10.758 1.00 7.75 ? 150 GLY A C 1 ATOM 898 O O . GLY A 1 117 ? -0.531 17.609 9.722 1.00 7.63 ? 150 GLY A O 1 ATOM 899 N N . ASN A 1 118 ? -1.131 16.342 11.430 1.00 8.23 ? 151 ASN A N 1 ATOM 900 C CA . ASN A 1 118 ? -0.245 15.258 11.013 1.00 8.38 ? 151 ASN A CA 1 ATOM 901 C C . ASN A 1 118 ? -0.754 14.534 9.772 1.00 8.35 ? 151 ASN A C 1 ATOM 902 O O . ASN A 1 118 ? 0.071 13.943 9.068 1.00 8.29 ? 151 ASN A O 1 ATOM 903 C CB . ASN A 1 118 ? -0.019 14.286 12.167 1.00 8.67 ? 151 ASN A CB 1 ATOM 904 C CG . ASN A 1 118 ? -1.304 13.681 12.639 1.00 9.21 ? 151 ASN A CG 1 ATOM 905 O OD1 . ASN A 1 118 ? -2.304 14.382 12.959 1.00 9.17 ? 151 ASN A OD1 1 ATOM 906 N ND2 . ASN A 1 118 ? -1.319 12.380 12.650 1.00 9.33 ? 151 ASN A ND2 1 ATOM 907 N N . HIS A 1 119 ? -2.082 14.579 9.528 1.00 8.12 ? 152 HIS A N 1 ATOM 908 C CA . HIS A 1 119 ? -2.718 14.121 8.285 1.00 7.87 ? 152 HIS A CA 1 ATOM 909 C C . HIS A 1 119 ? -2.739 15.154 7.176 1.00 9.02 ? 152 HIS A C 1 ATOM 910 O O . HIS A 1 119 ? -3.210 14.869 6.102 1.00 9.41 ? 152 HIS A O 1 ATOM 911 C CB . HIS A 1 119 ? -4.143 13.700 8.512 1.00 7.56 ? 152 HIS A CB 1 ATOM 912 C CG . HIS A 1 119 ? -4.265 12.435 9.291 1.00 7.95 ? 152 HIS A CG 1 ATOM 913 N ND1 . HIS A 1 119 ? -4.509 11.210 8.696 1.00 7.80 ? 152 HIS A ND1 1 ATOM 914 C CD2 . HIS A 1 119 ? -4.152 12.193 10.625 1.00 8.08 ? 152 HIS A CD2 1 ATOM 915 C CE1 . HIS A 1 119 ? -4.546 10.277 9.629 1.00 7.97 ? 152 HIS A CE1 1 ATOM 916 N NE2 . HIS A 1 119 ? -4.327 10.841 10.807 1.00 7.97 ? 152 HIS A NE2 1 ATOM 917 N N . ASP A 1 120 ? -2.257 16.375 7.396 1.00 9.91 ? 153 ASP A N 1 ATOM 918 C CA . ASP A 1 120 ? -2.192 17.354 6.312 1.00 10.13 ? 153 ASP A CA 1 ATOM 919 C C . ASP A 1 120 ? -0.892 17.253 5.497 1.00 11.08 ? 153 ASP A C 1 ATOM 920 O O . ASP A 1 120 ? -0.233 18.259 5.208 1.00 10.82 ? 153 ASP A O 1 ATOM 921 C CB . ASP A 1 120 ? -2.357 18.738 6.903 1.00 9.92 ? 153 ASP A CB 1 ATOM 922 C CG . ASP A 1 120 ? -3.734 18.950 7.483 1.00 9.29 ? 153 ASP A CG 1 ATOM 923 O OD1 . ASP A 1 120 ? -4.641 18.178 7.096 1.00 8.39 ? 153 ASP A OD1 1 ATOM 924 O OD2 . ASP A 1 120 ? -3.870 19.854 8.358 1.00 8.87 -1 153 ASP A OD2 1 ATOM 925 N N . TYR A 1 121 ? -0.513 16.014 5.182 1.00 11.69 ? 154 TYR A N 1 ATOM 926 C CA . TYR A 1 121 ? 0.692 15.732 4.401 1.00 12.29 ? 154 TYR A CA 1 ATOM 927 C C . TYR A 1 121 ? 0.562 14.313 3.877 1.00 13.12 ? 154 TYR A C 1 ATOM 928 O O . TYR A 1 121 ? -0.082 13.453 4.471 1.00 14.21 ? 154 TYR A O 1 ATOM 929 C CB . TYR A 1 121 ? 1.961 15.865 5.249 1.00 12.47 ? 154 TYR A CB 1 ATOM 930 C CG . TYR A 1 121 ? 3.255 16.026 4.420 1.00 12.63 ? 154 TYR A CG 1 ATOM 931 C CD1 . TYR A 1 121 ? 3.642 17.281 3.910 1.00 11.84 ? 154 TYR A CD1 1 ATOM 932 C CD2 . TYR A 1 121 ? 4.086 14.929 4.160 1.00 12.31 ? 154 TYR A CD2 1 ATOM 933 C CE1 . TYR A 1 121 ? 4.784 17.418 3.186 1.00 12.21 ? 154 TYR A CE1 1 ATOM 934 C CE2 . TYR A 1 121 ? 5.228 15.079 3.437 1.00 11.74 ? 154 TYR A CE2 1 ATOM 935 C CZ . TYR A 1 121 ? 5.562 16.305 2.935 1.00 12.34 ? 154 TYR A CZ 1 ATOM 936 O OH . TYR A 1 121 ? 6.706 16.432 2.155 1.00 13.74 ? 154 TYR A OH 1 ATOM 937 N N . TRP A 1 122 ? 1.143 14.063 2.739 1.00 14.31 ? 155 TRP A N 1 ATOM 938 C CA . TRP A 1 122 ? 1.270 12.694 2.262 1.00 15.46 ? 155 TRP A CA 1 ATOM 939 C C . TRP A 1 122 ? 2.757 12.302 2.162 1.00 15.34 ? 155 TRP A C 1 ATOM 940 O O . TRP A 1 122 ? 3.549 13.012 1.524 1.00 16.30 ? 155 TRP A O 1 ATOM 941 C CB . TRP A 1 122 ? 0.575 12.545 0.940 1.00 17.22 ? 155 TRP A CB 1 ATOM 942 C CG . TRP A 1 122 ? 0.409 11.163 0.649 1.00 20.13 ? 155 TRP A CG 1 ATOM 943 C CD1 . TRP A 1 122 ? -0.661 10.377 0.939 1.00 20.62 ? 155 TRP A CD1 1 ATOM 944 C CD2 . TRP A 1 122 ? 1.369 10.342 0.040 1.00 21.65 ? 155 TRP A CD2 1 ATOM 945 N NE1 . TRP A 1 122 ? -0.410 9.085 0.550 1.00 20.45 ? 155 TRP A NE1 1 ATOM 946 C CE2 . TRP A 1 122 ? 0.825 9.037 -0.017 1.00 21.59 ? 155 TRP A CE2 1 ATOM 947 C CE3 . TRP A 1 122 ? 2.644 10.578 -0.483 1.00 20.51 ? 155 TRP A CE3 1 ATOM 948 C CZ2 . TRP A 1 122 ? 1.507 7.976 -0.588 1.00 22.80 ? 155 TRP A CZ2 1 ATOM 949 C CZ3 . TRP A 1 122 ? 3.327 9.537 -1.032 1.00 21.75 ? 155 TRP A CZ3 1 ATOM 950 C CH2 . TRP A 1 122 ? 2.764 8.246 -1.099 1.00 22.87 ? 155 TRP A CH2 1 ATOM 951 N N . PRO A 1 123 ? 3.177 11.239 2.839 1.00 13.74 ? 156 PRO A N 1 ATOM 952 C CA . PRO A 1 123 ? 2.356 10.413 3.715 1.00 13.33 ? 156 PRO A CA 1 ATOM 953 C C . PRO A 1 123 ? 2.149 10.958 5.122 1.00 13.44 ? 156 PRO A C 1 ATOM 954 O O . PRO A 1 123 ? 3.033 11.553 5.708 1.00 13.74 ? 156 PRO A O 1 ATOM 955 C CB . PRO A 1 123 ? 3.177 9.136 3.829 1.00 13.12 ? 156 PRO A CB 1 ATOM 956 C CG . PRO A 1 123 ? 4.593 9.583 3.707 1.00 12.96 ? 156 PRO A CG 1 ATOM 957 C CD . PRO A 1 123 ? 4.569 10.765 2.764 1.00 13.29 ? 156 PRO A CD 1 ATOM 958 N N . GLN A 1 124 ? 1.014 10.655 5.712 1.00 13.61 ? 157 GLN A N 1 ATOM 959 C CA . GLN A 1 124 ? 0.702 11.184 7.000 1.00 12.97 ? 157 GLN A CA 1 ATOM 960 C C . GLN A 1 124 ? 1.889 11.097 7.920 1.00 13.16 ? 157 GLN A C 1 ATOM 961 O O . GLN A 1 124 ? 2.679 10.168 7.854 1.00 12.29 ? 157 GLN A O 1 ATOM 962 C CB . GLN A 1 124 ? -0.486 10.485 7.615 1.00 12.77 ? 157 GLN A CB 1 ATOM 963 C CG . GLN A 1 124 ? -0.232 9.061 8.025 1.00 13.15 ? 157 GLN A CG 1 ATOM 964 C CD . GLN A 1 124 ? -1.371 8.496 8.846 1.00 13.04 ? 157 GLN A CD 1 ATOM 965 O OE1 . GLN A 1 124 ? -2.280 7.952 8.292 1.00 14.10 ? 157 GLN A OE1 1 ATOM 966 N NE2 . GLN A 1 124 ? -1.348 8.693 10.150 1.00 12.83 ? 157 GLN A NE2 1 ATOM 967 N N . ASP A 1 125 ? 2.013 12.136 8.745 1.00 13.30 ? 158 ASP A N 1 ATOM 968 C CA . ASP A 1 125 ? 2.986 12.215 9.823 1.00 13.53 ? 158 ASP A CA 1 ATOM 969 C C . ASP A 1 125 ? 4.420 12.566 9.406 1.00 13.61 ? 158 ASP A C 1 ATOM 970 O O . ASP A 1 125 ? 5.249 12.923 10.267 1.00 13.90 ? 158 ASP A O 1 ATOM 971 C CB . ASP A 1 125 ? 3.061 10.923 10.635 1.00 13.65 ? 158 ASP A CB 1 ATOM 972 C CG . ASP A 1 125 ? 1.727 10.476 11.219 1.00 14.57 ? 158 ASP A CG 1 ATOM 973 O OD1 . ASP A 1 125 ? 0.722 11.199 11.233 1.00 16.70 ? 158 ASP A OD1 1 ATOM 974 O OD2 . ASP A 1 125 ? 1.659 9.335 11.674 1.00 15.38 -1 158 ASP A OD2 1 ATOM 975 N N . GLN A 1 126 ? 4.757 12.472 8.137 1.00 12.84 ? 159 GLN A N 1 ATOM 976 C CA . GLN A 1 126 ? 6.168 12.537 7.808 1.00 13.06 ? 159 GLN A CA 1 ATOM 977 C C . GLN A 1 126 ? 6.445 13.952 7.348 1.00 13.59 ? 159 GLN A C 1 ATOM 978 O O . GLN A 1 126 ? 6.906 14.160 6.238 1.00 14.38 ? 159 GLN A O 1 ATOM 979 C CB . GLN A 1 126 ? 6.533 11.528 6.726 1.00 13.17 ? 159 GLN A CB 1 ATOM 980 C CG . GLN A 1 126 ? 6.180 10.090 7.049 1.00 13.17 ? 159 GLN A CG 1 ATOM 981 C CD . GLN A 1 126 ? 6.841 9.604 8.309 1.00 13.49 ? 159 GLN A CD 1 ATOM 982 O OE1 . GLN A 1 126 ? 8.011 9.911 8.566 1.00 13.85 ? 159 GLN A OE1 1 ATOM 983 N NE2 . GLN A 1 126 ? 6.090 8.872 9.135 1.00 13.42 ? 159 GLN A NE2 1 ATOM 984 N N . LEU A 1 127 ? 6.135 14.949 8.178 1.00 13.55 ? 160 LEU A N 1 ATOM 985 C CA . LEU A 1 127 ? 6.228 16.310 7.725 1.00 13.01 ? 160 LEU A CA 1 ATOM 986 C C . LEU A 1 127 ? 7.657 16.736 7.763 1.00 13.70 ? 160 LEU A C 1 ATOM 987 O O . LEU A 1 127 ? 8.363 16.502 8.767 1.00 13.77 ? 160 LEU A O 1 ATOM 988 C CB . LEU A 1 127 ? 5.381 17.225 8.575 1.00 13.60 ? 160 LEU A CB 1 ATOM 989 C CG . LEU A 1 127 ? 3.890 17.199 8.170 1.00 13.74 ? 160 LEU A CG 1 ATOM 990 C CD1 . LEU A 1 127 ? 3.090 16.002 8.695 1.00 13.20 ? 160 LEU A CD1 1 ATOM 991 C CD2 . LEU A 1 127 ? 3.247 18.484 8.589 1.00 13.57 ? 160 LEU A CD2 1 ATOM 992 N N . PRO A 1 128 ? 8.115 17.358 6.673 1.00 13.57 ? 161 PRO A N 1 ATOM 993 C CA . PRO A 1 128 ? 9.520 17.712 6.507 1.00 13.62 ? 161 PRO A CA 1 ATOM 994 C C . PRO A 1 128 ? 9.926 19.045 7.127 1.00 14.03 ? 161 PRO A C 1 ATOM 995 O O . PRO A 1 128 ? 9.083 19.908 7.476 1.00 14.24 ? 161 PRO A O 1 ATOM 996 C CB . PRO A 1 128 ? 9.653 17.821 4.990 1.00 13.03 ? 161 PRO A CB 1 ATOM 997 C CG . PRO A 1 128 ? 8.351 18.423 4.602 1.00 13.35 ? 161 PRO A CG 1 ATOM 998 C CD . PRO A 1 128 ? 7.322 17.780 5.512 1.00 13.61 ? 161 PRO A CD 1 ATOM 999 N N . VAL A 1 129 ? 11.230 19.197 7.144 1.00 13.85 ? 162 VAL A N 1 ATOM 1000 C CA . VAL A 1 129 ? 11.960 20.340 7.689 1.00 14.43 ? 162 VAL A CA 1 ATOM 1001 C C . VAL A 1 129 ? 12.296 21.445 6.646 1.00 13.47 ? 162 VAL A C 1 ATOM 1002 O O . VAL A 1 129 ? 12.720 22.525 7.002 1.00 12.30 ? 162 VAL A O 1 ATOM 1003 C CB . VAL A 1 129 ? 13.247 19.754 8.287 1.00 15.57 ? 162 VAL A CB 1 ATOM 1004 C CG1 . VAL A 1 129 ? 14.413 20.671 8.174 1.00 17.71 ? 162 VAL A CG1 1 ATOM 1005 C CG2 . VAL A 1 129 ? 13.027 19.339 9.739 1.00 15.54 ? 162 VAL A CG2 1 ATOM 1006 N N . VAL A 1 130 ? 12.080 21.163 5.365 1.00 12.61 ? 163 VAL A N 1 ATOM 1007 C CA . VAL A 1 130 ? 12.406 22.093 4.293 1.00 11.90 ? 163 VAL A CA 1 ATOM 1008 C C . VAL A 1 130 ? 11.136 22.279 3.503 1.00 11.19 ? 163 VAL A C 1 ATOM 1009 O O . VAL A 1 130 ? 10.189 21.585 3.768 1.00 11.46 ? 163 VAL A O 1 ATOM 1010 C CB . VAL A 1 130 ? 13.529 21.523 3.405 1.00 12.34 ? 163 VAL A CB 1 ATOM 1011 C CG1 . VAL A 1 130 ? 14.821 21.400 4.189 1.00 12.75 ? 163 VAL A CG1 1 ATOM 1012 C CG2 . VAL A 1 130 ? 13.195 20.130 2.931 1.00 12.56 ? 163 VAL A CG2 1 ATOM 1013 N N . THR A 1 131 ? 11.106 23.219 2.573 1.00 10.61 ? 164 THR A N 1 ATOM 1014 C CA . THR A 1 131 ? 9.935 23.491 1.763 1.00 11.00 ? 164 THR A CA 1 ATOM 1015 C C . THR A 1 131 ? 9.505 22.194 1.045 1.00 11.14 ? 164 THR A C 1 ATOM 1016 O O . THR A 1 131 ? 10.278 21.246 0.962 1.00 10.84 ? 164 THR A O 1 ATOM 1017 C CB . THR A 1 131 ? 10.200 24.643 0.754 1.00 11.33 ? 164 THR A CB 1 ATOM 1018 O OG1 . THR A 1 131 ? 8.981 25.114 0.164 1.00 11.86 ? 164 THR A OG1 1 ATOM 1019 C CG2 . THR A 1 131 ? 11.030 24.153 -0.383 1.00 11.80 ? 164 THR A CG2 1 ATOM 1020 N N . SER A 1 132 ? 8.273 22.160 0.551 1.00 11.48 ? 165 SER A N 1 ATOM 1021 C CA . SER A 1 132 ? 7.625 20.915 0.098 1.00 11.66 ? 165 SER A CA 1 ATOM 1022 C C . SER A 1 132 ? 6.446 21.341 -0.694 1.00 11.95 ? 165 SER A C 1 ATOM 1023 O O . SER A 1 132 ? 5.997 22.450 -0.534 1.00 13.21 ? 165 SER A O 1 ATOM 1024 C CB . SER A 1 132 ? 7.153 20.089 1.288 1.00 12.20 ? 165 SER A CB 1 ATOM 1025 O OG . SER A 1 132 ? 5.977 20.680 1.928 1.00 14.09 ? 165 SER A OG 1 ATOM 1026 N N . LYS A 1 133 ? 5.889 20.511 -1.552 1.00 13.42 ? 166 LYS A N 1 ATOM 1027 C CA . LYS A 1 133 ? 4.728 20.992 -2.342 1.00 14.39 ? 166 LYS A CA 1 ATOM 1028 C C . LYS A 1 133 ? 3.546 21.464 -1.450 1.00 13.08 ? 166 LYS A C 1 ATOM 1029 O O . LYS A 1 133 ? 2.868 22.434 -1.761 1.00 12.10 ? 166 LYS A O 1 ATOM 1030 C CB . LYS A 1 133 ? 4.230 19.964 -3.363 1.00 15.41 ? 166 LYS A CB 1 ATOM 1031 C CG . LYS A 1 133 ? 3.237 20.643 -4.297 1.00 17.37 ? 166 LYS A CG 1 ATOM 1032 C CD . LYS A 1 133 ? 2.763 19.727 -5.368 1.00 19.94 ? 166 LYS A CD 1 ATOM 1033 C CE . LYS A 1 133 ? 3.832 19.545 -6.430 1.00 21.84 ? 166 LYS A CE 1 ATOM 1034 N NZ . LYS A 1 133 ? 3.467 20.308 -7.670 1.00 23.83 1 166 LYS A NZ 1 ATOM 1035 N N . VAL A 1 134 ? 3.350 20.763 -0.339 1.00 12.47 ? 167 VAL A N 1 ATOM 1036 C CA . VAL A 1 134 ? 2.205 20.973 0.519 1.00 12.42 ? 167 VAL A CA 1 ATOM 1037 C C . VAL A 1 134 ? 2.364 22.309 1.201 1.00 11.40 ? 167 VAL A C 1 ATOM 1038 O O . VAL A 1 134 ? 1.466 23.139 1.174 1.00 11.84 ? 167 VAL A O 1 ATOM 1039 C CB . VAL A 1 134 ? 2.074 19.865 1.603 1.00 12.73 ? 167 VAL A CB 1 ATOM 1040 C CG1 . VAL A 1 134 ? 1.031 20.249 2.636 1.00 12.93 ? 167 VAL A CG1 1 ATOM 1041 C CG2 . VAL A 1 134 ? 1.691 18.546 1.013 1.00 12.25 ? 167 VAL A CG2 1 ATOM 1042 N N . TYR A 1 135 ? 3.520 22.516 1.789 1.00 10.75 ? 168 TYR A N 1 ATOM 1043 C CA . TYR A 1 135 ? 3.791 23.787 2.435 1.00 10.65 ? 168 TYR A CA 1 ATOM 1044 C C . TYR A 1 135 ? 3.586 24.949 1.446 1.00 11.30 ? 168 TYR A C 1 ATOM 1045 O O . TYR A 1 135 ? 2.969 25.955 1.807 1.00 11.95 ? 168 TYR A O 1 ATOM 1046 C CB . TYR A 1 135 ? 5.202 23.821 3.031 1.00 9.98 ? 168 TYR A CB 1 ATOM 1047 C CG . TYR A 1 135 ? 5.540 22.851 4.157 1.00 9.29 ? 168 TYR A CG 1 ATOM 1048 C CD1 . TYR A 1 135 ? 4.581 22.210 4.933 1.00 8.87 ? 168 TYR A CD1 1 ATOM 1049 C CD2 . TYR A 1 135 ? 6.843 22.678 4.510 1.00 9.20 ? 168 TYR A CD2 1 ATOM 1050 C CE1 . TYR A 1 135 ? 4.949 21.364 5.980 1.00 8.60 ? 168 TYR A CE1 1 ATOM 1051 C CE2 . TYR A 1 135 ? 7.216 21.881 5.573 1.00 9.06 ? 168 TYR A CE2 1 ATOM 1052 C CZ . TYR A 1 135 ? 6.277 21.203 6.309 1.00 8.83 ? 168 TYR A CZ 1 ATOM 1053 O OH . TYR A 1 135 ? 6.766 20.346 7.330 1.00 8.64 ? 168 TYR A OH 1 ATOM 1054 N N . ASN A 1 136 ? 4.027 24.807 0.190 1.00 11.21 ? 169 ASN A N 1 ATOM 1055 C CA . ASN A 1 136 ? 3.812 25.867 -0.777 1.00 11.47 ? 169 ASN A CA 1 ATOM 1056 C C . ASN A 1 136 ? 2.350 25.927 -1.201 1.00 12.34 ? 169 ASN A C 1 ATOM 1057 O O . ASN A 1 136 ? 1.801 26.995 -1.556 1.00 14.56 ? 169 ASN A O 1 ATOM 1058 C CB . ASN A 1 136 ? 4.717 25.668 -2.000 1.00 12.11 ? 169 ASN A CB 1 ATOM 1059 C CG . ASN A 1 136 ? 6.208 25.891 -1.689 1.00 12.62 ? 169 ASN A CG 1 ATOM 1060 O OD1 . ASN A 1 136 ? 7.048 24.979 -1.664 1.00 11.68 ? 169 ASN A OD1 1 ATOM 1061 N ND2 . ASN A 1 136 ? 6.537 27.136 -1.465 1.00 13.21 ? 169 ASN A ND2 1 ATOM 1062 N N . ALA A 1 137 ? 1.655 24.807 -1.193 1.00 12.29 ? 170 ALA A N 1 ATOM 1063 C CA . ALA A 1 137 ? 0.219 24.898 -1.501 1.00 12.36 ? 170 ALA A CA 1 ATOM 1064 C C . ALA A 1 137 ? -0.570 25.614 -0.404 1.00 12.35 ? 170 ALA A C 1 ATOM 1065 O O . ALA A 1 137 ? -1.469 26.403 -0.695 1.00 13.00 ? 170 ALA A O 1 ATOM 1066 C CB . ALA A 1 137 ? -0.372 23.516 -1.758 1.00 12.62 ? 170 ALA A CB 1 ATOM 1067 N N . VAL A 1 138 ? -0.260 25.347 0.856 1.00 11.68 ? 171 VAL A N 1 ATOM 1068 C CA . VAL A 1 138 ? -1.092 25.947 1.921 1.00 12.29 ? 171 VAL A CA 1 ATOM 1069 C C . VAL A 1 138 ? -0.774 27.434 1.992 1.00 12.73 ? 171 VAL A C 1 ATOM 1070 O O . VAL A 1 138 ? -1.651 28.240 2.183 1.00 12.96 ? 171 VAL A O 1 ATOM 1071 C CB . VAL A 1 138 ? -0.931 25.241 3.315 1.00 11.97 ? 171 VAL A CB 1 ATOM 1072 C CG1 . VAL A 1 138 ? -1.240 23.756 3.219 1.00 11.69 ? 171 VAL A CG1 1 ATOM 1073 C CG2 . VAL A 1 138 ? 0.476 25.416 3.873 1.00 11.87 ? 171 VAL A CG2 1 ATOM 1074 N N . ALA A 1 139 ? 0.496 27.782 1.812 1.00 14.10 ? 172 ALA A N 1 ATOM 1075 C CA . ALA A 1 139 ? 0.914 29.189 1.647 1.00 14.66 ? 172 ALA A CA 1 ATOM 1076 C C . ALA A 1 139 ? 0.065 29.925 0.587 1.00 14.70 ? 172 ALA A C 1 ATOM 1077 O O . ALA A 1 139 ? -0.495 31.017 0.834 1.00 14.30 ? 172 ALA A O 1 ATOM 1078 C CB . ALA A 1 139 ? 2.394 29.256 1.308 1.00 14.57 ? 172 ALA A CB 1 ATOM 1079 N N . ASN A 1 140 ? -0.080 29.312 -0.570 1.00 15.21 ? 173 ASN A N 1 ATOM 1080 C CA . ASN A 1 140 ? -0.899 29.946 -1.571 1.00 16.87 ? 173 ASN A CA 1 ATOM 1081 C C . ASN A 1 140 ? -2.299 30.063 -1.118 1.00 16.20 ? 173 ASN A C 1 ATOM 1082 O O . ASN A 1 140 ? -2.880 31.126 -1.257 1.00 17.99 ? 173 ASN A O 1 ATOM 1083 C CB . ASN A 1 140 ? -0.849 29.237 -2.906 1.00 19.15 ? 173 ASN A CB 1 ATOM 1084 C CG . ASN A 1 140 ? 0.528 29.291 -3.511 1.00 22.21 ? 173 ASN A CG 1 ATOM 1085 O OD1 . ASN A 1 140 ? 1.307 30.218 -3.242 1.00 26.17 ? 173 ASN A OD1 1 ATOM 1086 N ND2 . ASN A 1 140 ? 0.866 28.277 -4.289 1.00 23.32 ? 173 ASN A ND2 1 ATOM 1087 N N . LEU A 1 141 ? -2.848 28.991 -0.572 1.00 15.14 ? 174 LEU A N 1 ATOM 1088 C CA . LEU A 1 141 ? -4.247 28.986 -0.171 1.00 14.29 ? 174 LEU A CA 1 ATOM 1089 C C . LEU A 1 141 ? -4.539 29.928 0.970 1.00 13.70 ? 174 LEU A C 1 ATOM 1090 O O . LEU A 1 141 ? -5.655 30.428 1.055 1.00 13.67 ? 174 LEU A O 1 ATOM 1091 C CB . LEU A 1 141 ? -4.650 27.598 0.268 1.00 15.10 ? 174 LEU A CB 1 ATOM 1092 C CG . LEU A 1 141 ? -4.671 26.599 -0.879 1.00 15.40 ? 174 LEU A CG 1 ATOM 1093 C CD1 . LEU A 1 141 ? -4.522 25.218 -0.275 1.00 16.11 ? 174 LEU A CD1 1 ATOM 1094 C CD2 . LEU A 1 141 ? -5.964 26.705 -1.676 1.00 14.97 ? 174 LEU A CD2 1 ATOM 1095 N N . TRP A 1 142 ? -3.567 30.161 1.856 1.00 13.04 ? 175 TRP A N 1 ATOM 1096 C CA . TRP A 1 142 ? -3.825 30.927 3.077 1.00 12.91 ? 175 TRP A CA 1 ATOM 1097 C C . TRP A 1 142 ? -3.350 32.401 3.014 1.00 15.00 ? 175 TRP A C 1 ATOM 1098 O O . TRP A 1 142 ? -3.452 33.149 3.984 1.00 15.14 ? 175 TRP A O 1 ATOM 1099 C CB . TRP A 1 142 ? -3.236 30.194 4.268 1.00 11.65 ? 175 TRP A CB 1 ATOM 1100 C CG . TRP A 1 142 ? -3.805 28.828 4.493 1.00 10.36 ? 175 TRP A CG 1 ATOM 1101 C CD1 . TRP A 1 142 ? -4.999 28.347 4.045 1.00 10.05 ? 175 TRP A CD1 1 ATOM 1102 C CD2 . TRP A 1 142 ? -3.206 27.773 5.232 1.00 9.34 ? 175 TRP A CD2 1 ATOM 1103 N NE1 . TRP A 1 142 ? -5.163 27.047 4.445 1.00 9.39 ? 175 TRP A NE1 1 ATOM 1104 C CE2 . TRP A 1 142 ? -4.073 26.678 5.178 1.00 8.95 ? 175 TRP A CE2 1 ATOM 1105 C CE3 . TRP A 1 142 ? -1.998 27.644 5.919 1.00 9.53 ? 175 TRP A CE3 1 ATOM 1106 C CZ2 . TRP A 1 142 ? -3.800 25.497 5.788 1.00 8.97 ? 175 TRP A CZ2 1 ATOM 1107 C CZ3 . TRP A 1 142 ? -1.720 26.442 6.543 1.00 9.32 ? 175 TRP A CZ3 1 ATOM 1108 C CH2 . TRP A 1 142 ? -2.619 25.386 6.468 1.00 9.28 ? 175 TRP A CH2 1 ATOM 1109 N N . LYS A 1 143 ? -2.884 32.822 1.841 1.00 17.83 ? 176 LYS A N 1 ATOM 1110 C CA . LYS A 1 143 ? -2.509 34.216 1.571 1.00 18.63 ? 176 LYS A CA 1 ATOM 1111 C C . LYS A 1 143 ? -3.556 35.246 1.949 1.00 17.07 ? 176 LYS A C 1 ATOM 1112 O O . LYS A 1 143 ? -3.231 36.328 2.436 1.00 18.06 ? 176 LYS A O 1 ATOM 1113 C CB . LYS A 1 143 ? -2.234 34.369 0.086 1.00 22.99 ? 176 LYS A CB 1 ATOM 1114 C CG . LYS A 1 143 ? -0.774 34.239 -0.325 1.00 27.61 ? 176 LYS A CG 1 ATOM 1115 C CD . LYS A 1 143 ? -0.597 34.013 -1.835 1.00 31.92 ? 176 LYS A CD 1 ATOM 1116 C CE . LYS A 1 143 ? -1.719 34.633 -2.686 1.00 37.38 ? 176 LYS A CE 1 ATOM 1117 N NZ . LYS A 1 143 ? -2.312 33.657 -3.673 1.00 41.16 1 176 LYS A NZ 1 ATOM 1118 N N . PRO A 1 144 ? -4.826 34.948 1.707 1.00 16.06 ? 177 PRO A N 1 ATOM 1119 C CA . PRO A 1 144 ? -5.847 35.931 2.080 1.00 15.56 ? 177 PRO A CA 1 ATOM 1120 C C . PRO A 1 144 ? -5.878 36.304 3.569 1.00 16.31 ? 177 PRO A C 1 ATOM 1121 O O . PRO A 1 144 ? -6.374 37.402 3.960 1.00 16.32 ? 177 PRO A O 1 ATOM 1122 C CB . PRO A 1 144 ? -7.151 35.214 1.709 1.00 15.58 ? 177 PRO A CB 1 ATOM 1123 C CG . PRO A 1 144 ? -6.769 34.318 0.564 1.00 15.14 ? 177 PRO A CG 1 ATOM 1124 C CD . PRO A 1 144 ? -5.400 33.814 0.949 1.00 15.73 ? 177 PRO A CD 1 ATOM 1125 N N . TRP A 1 145 ? -5.362 35.394 4.398 1.00 15.67 ? 178 TRP A N 1 ATOM 1126 C CA . TRP A 1 145 ? -5.427 35.551 5.845 1.00 15.10 ? 178 TRP A CA 1 ATOM 1127 C C . TRP A 1 145 ? -4.104 36.001 6.435 1.00 15.25 ? 178 TRP A C 1 ATOM 1128 O O . TRP A 1 145 ? -4.077 36.532 7.507 1.00 14.24 ? 178 TRP A O 1 ATOM 1129 C CB . TRP A 1 145 ? -5.825 34.213 6.509 1.00 14.12 ? 178 TRP A CB 1 ATOM 1130 C CG . TRP A 1 145 ? -7.163 33.727 6.178 1.00 12.37 ? 178 TRP A CG 1 ATOM 1131 C CD1 . TRP A 1 145 ? -8.232 34.460 6.024 1.00 12.30 ? 178 TRP A CD1 1 ATOM 1132 C CD2 . TRP A 1 145 ? -7.565 32.367 6.003 1.00 11.77 ? 178 TRP A CD2 1 ATOM 1133 N NE1 . TRP A 1 145 ? -9.316 33.672 5.752 1.00 12.38 ? 178 TRP A NE1 1 ATOM 1134 C CE2 . TRP A 1 145 ? -8.918 32.373 5.725 1.00 11.56 ? 178 TRP A CE2 1 ATOM 1135 C CE3 . TRP A 1 145 ? -6.896 31.141 6.059 1.00 12.02 ? 178 TRP A CE3 1 ATOM 1136 C CZ2 . TRP A 1 145 ? -9.647 31.222 5.529 1.00 11.93 ? 178 TRP A CZ2 1 ATOM 1137 C CZ3 . TRP A 1 145 ? -7.615 29.975 5.837 1.00 12.13 ? 178 TRP A CZ3 1 ATOM 1138 C CH2 . TRP A 1 145 ? -8.974 30.023 5.563 1.00 12.10 ? 178 TRP A CH2 1 ATOM 1139 N N . LEU A 1 146 ? -3.007 35.754 5.755 1.00 16.53 ? 179 LEU A N 1 ATOM 1140 C CA . LEU A 1 146 ? -1.698 35.996 6.346 1.00 18.26 ? 179 LEU A CA 1 ATOM 1141 C C . LEU A 1 146 ? -0.865 36.985 5.508 1.00 19.32 ? 179 LEU A C 1 ATOM 1142 O O . LEU A 1 146 ? -1.109 37.130 4.297 1.00 20.21 ? 179 LEU A O 1 ATOM 1143 C CB . LEU A 1 146 ? -0.987 34.628 6.476 1.00 18.93 ? 179 LEU A CB 1 ATOM 1144 C CG . LEU A 1 146 ? -1.852 33.560 7.181 1.00 18.75 ? 179 LEU A CG 1 ATOM 1145 C CD1 . LEU A 1 146 ? -1.112 32.236 7.270 1.00 19.65 ? 179 LEU A CD1 1 ATOM 1146 C CD2 . LEU A 1 146 ? -2.264 33.970 8.581 1.00 17.88 ? 179 LEU A CD2 1 ATOM 1147 N N . ASP A 1 147 ? 0.090 37.657 6.163 1.00 20.29 ? 180 ASP A N 1 ATOM 1148 C CA . ASP A 1 147 ? 1.089 38.543 5.525 1.00 20.57 ? 180 ASP A CA 1 ATOM 1149 C C . ASP A 1 147 ? 2.275 37.769 4.943 1.00 20.95 ? 180 ASP A C 1 ATOM 1150 O O . ASP A 1 147 ? 2.489 36.611 5.286 1.00 22.21 ? 180 ASP A O 1 ATOM 1151 C CB . ASP A 1 147 ? 1.619 39.529 6.549 1.00 22.42 ? 180 ASP A CB 1 ATOM 1152 C CG . ASP A 1 147 ? 0.543 40.488 7.057 1.00 27.33 ? 180 ASP A CG 1 ATOM 1153 O OD1 . ASP A 1 147 ? -0.496 40.659 6.361 1.00 30.66 ? 180 ASP A OD1 1 ATOM 1154 O OD2 . ASP A 1 147 ? 0.727 41.106 8.159 1.00 32.82 -1 180 ASP A OD2 1 ATOM 1155 N N . GLU A 1 148 ? 3.045 38.433 4.084 1.00 21.77 ? 181 GLU A N 1 ATOM 1156 C CA . GLU A 1 148 ? 4.194 37.883 3.382 1.00 23.04 ? 181 GLU A CA 1 ATOM 1157 C C . GLU A 1 148 ? 5.214 37.247 4.266 1.00 20.37 ? 181 GLU A C 1 ATOM 1158 O O . GLU A 1 148 ? 5.880 36.328 3.857 1.00 18.57 ? 181 GLU A O 1 ATOM 1159 C CB . GLU A 1 148 ? 4.951 38.989 2.649 1.00 30.98 ? 181 GLU A CB 1 ATOM 1160 C CG . GLU A 1 148 ? 4.169 39.771 1.599 1.00 40.29 ? 181 GLU A CG 1 ATOM 1161 C CD . GLU A 1 148 ? 4.726 41.194 1.349 1.00 51.01 ? 181 GLU A CD 1 ATOM 1162 O OE1 . GLU A 1 148 ? 4.787 41.583 0.151 1.00 54.19 ? 181 GLU A OE1 1 ATOM 1163 O OE2 . GLU A 1 148 ? 5.093 41.925 2.326 1.00 52.11 -1 181 GLU A OE2 1 ATOM 1164 N N . GLU A 1 149 ? 5.400 37.789 5.459 1.00 19.51 ? 182 GLU A N 1 ATOM 1165 C CA . GLU A 1 149 ? 6.415 37.297 6.358 1.00 20.00 ? 182 GLU A CA 1 ATOM 1166 C C . GLU A 1 149 ? 5.992 35.935 6.896 1.00 16.68 ? 182 GLU A C 1 ATOM 1167 O O . GLU A 1 149 ? 6.779 34.994 6.970 1.00 17.24 ? 182 GLU A O 1 ATOM 1168 C CB . GLU A 1 149 ? 6.678 38.319 7.449 1.00 23.92 ? 182 GLU A CB 1 ATOM 1169 C CG . GLU A 1 149 ? 7.195 39.678 6.916 1.00 30.52 ? 182 GLU A CG 1 ATOM 1170 C CD . GLU A 1 149 ? 6.154 40.837 6.649 1.00 34.65 ? 182 GLU A CD 1 ATOM 1171 O OE1 . GLU A 1 149 ? 4.906 40.655 6.521 1.00 31.53 ? 182 GLU A OE1 1 ATOM 1172 O OE2 . GLU A 1 149 ? 6.639 42.008 6.567 1.00 39.40 -1 182 GLU A OE2 1 ATOM 1173 N N . ALA A 1 150 ? 4.725 35.807 7.180 1.00 13.85 ? 183 ALA A N 1 ATOM 1174 C CA . ALA A 1 150 ? 4.177 34.552 7.593 1.00 13.39 ? 183 ALA A CA 1 ATOM 1175 C C . ALA A 1 150 ? 4.078 33.569 6.463 1.00 13.59 ? 183 ALA A C 1 ATOM 1176 O O . ALA A 1 150 ? 4.303 32.390 6.678 1.00 13.48 ? 183 ALA A O 1 ATOM 1177 C CB . ALA A 1 150 ? 2.806 34.758 8.209 1.00 13.71 ? 183 ALA A CB 1 ATOM 1178 N N . ILE A 1 151 ? 3.652 34.020 5.292 1.00 13.97 ? 184 ILE A N 1 ATOM 1179 C CA . ILE A 1 151 ? 3.671 33.186 4.130 1.00 15.32 ? 184 ILE A CA 1 ATOM 1180 C C . ILE A 1 151 ? 5.086 32.673 3.853 1.00 16.77 ? 184 ILE A C 1 ATOM 1181 O O . ILE A 1 151 ? 5.239 31.534 3.516 1.00 18.91 ? 184 ILE A O 1 ATOM 1182 C CB . ILE A 1 151 ? 3.134 33.931 2.891 1.00 16.26 ? 184 ILE A CB 1 ATOM 1183 C CG1 . ILE A 1 151 ? 1.633 34.180 3.040 1.00 16.30 ? 184 ILE A CG1 1 ATOM 1184 C CG2 . ILE A 1 151 ? 3.334 33.074 1.646 1.00 16.62 ? 184 ILE A CG2 1 ATOM 1185 C CD1 . ILE A 1 151 ? 0.866 32.942 3.532 1.00 16.58 ? 184 ILE A CD1 1 ATOM 1186 N N . SER A 1 152 ? 6.128 33.470 4.015 1.00 17.31 ? 185 SER A N 1 ATOM 1187 C CA . SER A 1 152 ? 7.474 32.942 3.782 1.00 18.29 ? 185 SER A CA 1 ATOM 1188 C C . SER A 1 152 ? 7.719 31.778 4.622 1.00 17.94 ? 185 SER A C 1 ATOM 1189 O O . SER A 1 152 ? 8.172 30.794 4.144 1.00 24.69 ? 185 SER A O 1 ATOM 1190 C CB . SER A 1 152 ? 8.607 33.901 4.166 1.00 18.54 ? 185 SER A CB 1 ATOM 1191 O OG . SER A 1 152 ? 8.565 34.993 3.349 1.00 21.11 ? 185 SER A OG 1 ATOM 1192 N N . THR A 1 153 ? 7.518 31.931 5.907 1.00 16.24 ? 186 THR A N 1 ATOM 1193 C CA . THR A 1 153 ? 7.981 30.947 6.864 1.00 14.96 ? 186 THR A CA 1 ATOM 1194 C C . THR A 1 153 ? 7.136 29.706 6.703 1.00 13.60 ? 186 THR A C 1 ATOM 1195 O O . THR A 1 153 ? 7.614 28.610 6.793 1.00 12.91 ? 186 THR A O 1 ATOM 1196 C CB . THR A 1 153 ? 7.871 31.572 8.266 1.00 14.66 ? 186 THR A CB 1 ATOM 1197 O OG1 . THR A 1 153 ? 8.685 32.735 8.268 1.00 14.57 ? 186 THR A OG1 1 ATOM 1198 C CG2 . THR A 1 153 ? 8.437 30.734 9.276 1.00 14.96 ? 186 THR A CG2 1 ATOM 1199 N N . LEU A 1 154 ? 5.883 29.892 6.368 1.00 12.95 ? 187 LEU A N 1 ATOM 1200 C CA . LEU A 1 154 ? 5.039 28.771 6.172 1.00 13.51 ? 187 LEU A CA 1 ATOM 1201 C C . LEU A 1 154 ? 5.602 27.848 5.058 1.00 14.46 ? 187 LEU A C 1 ATOM 1202 O O . LEU A 1 154 ? 5.749 26.650 5.265 1.00 14.48 ? 187 LEU A O 1 ATOM 1203 C CB . LEU A 1 154 ? 3.662 29.282 5.860 1.00 13.22 ? 187 LEU A CB 1 ATOM 1204 C CG . LEU A 1 154 ? 2.475 28.359 5.730 1.00 13.45 ? 187 LEU A CG 1 ATOM 1205 C CD1 . LEU A 1 154 ? 2.313 27.418 6.911 1.00 13.24 ? 187 LEU A CD1 1 ATOM 1206 C CD2 . LEU A 1 154 ? 1.248 29.260 5.556 1.00 13.78 ? 187 LEU A CD2 1 ATOM 1207 N N . ARG A 1 155 ? 5.985 28.416 3.922 1.00 14.66 ? 188 ARG A N 1 ATOM 1208 C CA . ARG A 1 155 ? 6.604 27.659 2.848 1.00 15.37 ? 188 ARG A CA 1 ATOM 1209 C C . ARG A 1 155 ? 7.818 26.845 3.268 1.00 16.27 ? 188 ARG A C 1 ATOM 1210 O O . ARG A 1 155 ? 8.094 25.820 2.665 1.00 14.61 ? 188 ARG A O 1 ATOM 1211 C CB . ARG A 1 155 ? 7.083 28.580 1.753 1.00 15.81 ? 188 ARG A CB 1 ATOM 1212 C CG . ARG A 1 155 ? 6.010 29.397 1.059 1.00 16.05 ? 188 ARG A CG 1 ATOM 1213 C CD . ARG A 1 155 ? 6.627 30.149 -0.126 1.00 16.28 ? 188 ARG A CD 1 ATOM 1214 N NE . ARG A 1 155 ? 5.634 30.966 -0.783 1.00 16.42 ? 188 ARG A NE 1 ATOM 1215 C CZ . ARG A 1 155 ? 4.614 30.496 -1.486 1.00 17.31 ? 188 ARG A CZ 1 ATOM 1216 N NH1 . ARG A 1 155 ? 4.408 29.198 -1.673 1.00 18.62 1 188 ARG A NH1 1 ATOM 1217 N NH2 . ARG A 1 155 ? 3.763 31.333 -2.011 1.00 17.93 ? 188 ARG A NH2 1 ATOM 1218 N N . LYS A 1 156 ? 8.557 27.305 4.265 1.00 17.27 ? 189 LYS A N 1 ATOM 1219 C CA . LYS A 1 156 ? 9.835 26.663 4.589 1.00 18.82 ? 189 LYS A CA 1 ATOM 1220 C C . LYS A 1 156 ? 9.789 25.607 5.671 1.00 17.33 ? 189 LYS A C 1 ATOM 1221 O O . LYS A 1 156 ? 10.758 24.859 5.892 1.00 16.98 ? 189 LYS A O 1 ATOM 1222 C CB . LYS A 1 156 ? 10.843 27.722 5.016 1.00 22.63 ? 189 LYS A CB 1 ATOM 1223 C CG . LYS A 1 156 ? 11.506 28.436 3.844 1.00 29.51 ? 189 LYS A CG 1 ATOM 1224 C CD . LYS A 1 156 ? 11.153 29.915 3.735 1.00 36.47 ? 189 LYS A CD 1 ATOM 1225 C CE . LYS A 1 156 ? 11.587 30.476 2.371 1.00 43.66 ? 189 LYS A CE 1 ATOM 1226 N NZ . LYS A 1 156 ? 10.548 31.395 1.778 1.00 46.43 1 189 LYS A NZ 1 ATOM 1227 N N . GLY A 1 157 ? 8.706 25.620 6.428 1.00 16.40 ? 190 GLY A N 1 ATOM 1228 C CA . GLY A 1 157 ? 8.634 24.829 7.659 1.00 14.76 ? 190 GLY A CA 1 ATOM 1229 C C . GLY A 1 157 ? 7.237 24.527 8.141 1.00 13.26 ? 190 GLY A C 1 ATOM 1230 O O . GLY A 1 157 ? 7.102 23.762 9.066 1.00 12.97 ? 190 GLY A O 1 ATOM 1231 N N . GLY A 1 158 ? 6.217 25.073 7.489 1.00 11.85 ? 191 GLY A N 1 ATOM 1232 C CA . GLY A 1 158 ? 4.852 24.883 7.903 1.00 12.15 ? 191 GLY A CA 1 ATOM 1233 C C . GLY A 1 158 ? 4.436 25.571 9.203 1.00 12.32 ? 191 GLY A C 1 ATOM 1234 O O . GLY A 1 158 ? 3.476 25.154 9.835 1.00 12.40 ? 191 GLY A O 1 ATOM 1235 N N . PHE A 1 159 ? 5.178 26.606 9.606 1.00 12.46 ? 192 PHE A N 1 ATOM 1236 C CA . PHE A 1 159 ? 4.873 27.387 10.790 1.00 11.75 ? 192 PHE A CA 1 ATOM 1237 C C . PHE A 1 159 ? 4.937 28.860 10.445 1.00 11.25 ? 192 PHE A C 1 ATOM 1238 O O . PHE A 1 159 ? 5.520 29.204 9.428 1.00 11.90 ? 192 PHE A O 1 ATOM 1239 C CB . PHE A 1 159 ? 5.817 27.000 11.914 1.00 11.88 ? 192 PHE A CB 1 ATOM 1240 C CG . PHE A 1 159 ? 7.301 27.269 11.651 1.00 12.54 ? 192 PHE A CG 1 ATOM 1241 C CD1 . PHE A 1 159 ? 7.848 28.545 11.761 1.00 12.99 ? 192 PHE A CD1 1 ATOM 1242 C CD2 . PHE A 1 159 ? 8.183 26.216 11.440 1.00 12.77 ? 192 PHE A CD2 1 ATOM 1243 C CE1 . PHE A 1 159 ? 9.222 28.753 11.584 1.00 13.08 ? 192 PHE A CE1 1 ATOM 1244 C CE2 . PHE A 1 159 ? 9.550 26.413 11.278 1.00 12.48 ? 192 PHE A CE2 1 ATOM 1245 C CZ . PHE A 1 159 ? 10.064 27.687 11.320 1.00 12.67 ? 192 PHE A CZ 1 ATOM 1246 N N . TYR A 1 160 ? 4.305 29.722 11.248 1.00 10.26 ? 193 TYR A N 1 ATOM 1247 C CA . TYR A 1 160 ? 4.333 31.174 11.045 1.00 9.34 ? 193 TYR A CA 1 ATOM 1248 C C . TYR A 1 160 ? 3.873 31.926 12.287 1.00 9.71 ? 193 TYR A C 1 ATOM 1249 O O . TYR A 1 160 ? 3.245 31.329 13.165 1.00 10.45 ? 193 TYR A O 1 ATOM 1250 C CB . TYR A 1 160 ? 3.421 31.587 9.891 1.00 8.87 ? 193 TYR A CB 1 ATOM 1251 C CG . TYR A 1 160 ? 1.947 31.362 10.151 1.00 8.52 ? 193 TYR A CG 1 ATOM 1252 C CD1 . TYR A 1 160 ? 1.352 30.151 9.851 1.00 8.42 ? 193 TYR A CD1 1 ATOM 1253 C CD2 . TYR A 1 160 ? 1.155 32.339 10.709 1.00 8.22 ? 193 TYR A CD2 1 ATOM 1254 C CE1 . TYR A 1 160 ? 0.001 29.930 10.073 1.00 8.18 ? 193 TYR A CE1 1 ATOM 1255 C CE2 . TYR A 1 160 ? -0.177 32.120 10.955 1.00 8.10 ? 193 TYR A CE2 1 ATOM 1256 C CZ . TYR A 1 160 ? -0.756 30.899 10.633 1.00 8.18 ? 193 TYR A CZ 1 ATOM 1257 O OH . TYR A 1 160 ? -2.084 30.641 10.908 1.00 8.04 ? 193 TYR A OH 1 ATOM 1258 N N . SER A 1 161 ? 4.107 33.240 12.352 1.00 9.67 ? 194 SER A N 1 ATOM 1259 C CA . SER A 1 161 ? 3.343 34.066 13.296 1.00 9.61 ? 194 SER A CA 1 ATOM 1260 C C . SER A 1 161 ? 2.657 35.169 12.538 1.00 9.51 ? 194 SER A C 1 ATOM 1261 O O . SER A 1 161 ? 3.042 35.464 11.468 1.00 9.21 ? 194 SER A O 1 ATOM 1262 C CB . SER A 1 161 ? 4.202 34.636 14.427 1.00 9.67 ? 194 SER A CB 1 ATOM 1263 O OG . SER A 1 161 ? 4.915 35.792 14.022 1.00 9.96 ? 194 SER A OG 1 ATOM 1264 N N . GLN A 1 162 ? 1.622 35.757 13.112 1.00 10.09 ? 195 GLN A N 1 ATOM 1265 C CA . GLN A 1 162 ? 0.793 36.734 12.416 1.00 10.46 ? 195 GLN A CA 1 ATOM 1266 C C . GLN A 1 162 ? -0.023 37.533 13.426 1.00 10.76 ? 195 GLN A C 1 ATOM 1267 O O . GLN A 1 162 ? -0.557 36.964 14.326 1.00 11.03 ? 195 GLN A O 1 ATOM 1268 C CB . GLN A 1 162 ? -0.114 35.988 11.452 1.00 10.32 ? 195 GLN A CB 1 ATOM 1269 C CG . GLN A 1 162 ? -1.150 36.813 10.724 1.00 10.36 ? 195 GLN A CG 1 ATOM 1270 C CD . GLN A 1 162 ? -0.528 37.756 9.728 1.00 10.32 ? 195 GLN A CD 1 ATOM 1271 O OE1 . GLN A 1 162 ? 0.190 37.348 8.822 1.00 10.46 ? 195 GLN A OE1 1 ATOM 1272 N NE2 . GLN A 1 162 ? -0.835 39.018 9.866 1.00 10.10 ? 195 GLN A NE2 1 ATOM 1273 N N . LYS A 1 163 ? -0.063 38.853 13.273 1.00 11.55 ? 196 LYS A N 1 ATOM 1274 C CA . LYS A 1 163 ? -0.770 39.751 14.155 1.00 11.89 ? 196 LYS A CA 1 ATOM 1275 C C . LYS A 1 163 ? -2.220 39.759 13.715 1.00 12.27 ? 196 LYS A C 1 ATOM 1276 O O . LYS A 1 163 ? -2.482 39.574 12.547 1.00 12.38 ? 196 LYS A O 1 ATOM 1277 C CB . LYS A 1 163 ? -0.221 41.142 14.036 1.00 12.82 ? 196 LYS A CB 1 ATOM 1278 C CG . LYS A 1 163 ? 1.096 41.303 14.745 1.00 14.58 ? 196 LYS A CG 1 ATOM 1279 C CD . LYS A 1 163 ? 1.827 42.577 14.355 1.00 16.48 ? 196 LYS A CD 1 ATOM 1280 C CE . LYS A 1 163 ? 2.252 42.560 12.900 1.00 17.58 ? 196 LYS A CE 1 ATOM 1281 N NZ . LYS A 1 163 ? 3.315 43.546 12.739 1.00 18.06 1 196 LYS A NZ 1 ATOM 1282 N N . VAL A 1 164 ? -3.143 39.943 14.653 1.00 11.84 ? 197 VAL A N 1 ATOM 1283 C CA . VAL A 1 164 ? -4.542 39.822 14.373 1.00 12.53 ? 197 VAL A CA 1 ATOM 1284 C C . VAL A 1 164 ? -5.018 41.134 13.813 1.00 13.23 ? 197 VAL A C 1 ATOM 1285 O O . VAL A 1 164 ? -4.799 42.179 14.412 1.00 13.86 ? 197 VAL A O 1 ATOM 1286 C CB . VAL A 1 164 ? -5.360 39.530 15.676 1.00 12.32 ? 197 VAL A CB 1 ATOM 1287 C CG1 . VAL A 1 164 ? -6.869 39.536 15.412 1.00 12.15 ? 197 VAL A CG1 1 ATOM 1288 C CG2 . VAL A 1 164 ? -4.952 38.226 16.300 1.00 12.02 ? 197 VAL A CG2 1 ATOM 1289 N N . THR A 1 165 ? -5.740 41.108 12.711 1.00 14.33 ? 198 THR A N 1 ATOM 1290 C CA . THR A 1 165 ? -6.124 42.382 12.119 1.00 15.75 ? 198 THR A CA 1 ATOM 1291 C C . THR A 1 165 ? -6.956 43.292 12.995 1.00 15.39 ? 198 THR A C 1 ATOM 1292 O O . THR A 1 165 ? -6.765 44.468 12.939 1.00 15.73 ? 198 THR A O 1 ATOM 1293 C CB . THR A 1 165 ? -6.895 42.208 10.829 1.00 16.88 ? 198 THR A CB 1 ATOM 1294 O OG1 . THR A 1 165 ? -6.096 41.450 9.952 1.00 17.90 ? 198 THR A OG1 1 ATOM 1295 C CG2 . THR A 1 165 ? -7.165 43.560 10.191 1.00 17.22 ? 198 THR A CG2 1 ATOM 1296 N N . THR A 1 166 ? -7.893 42.742 13.748 1.00 15.27 ? 199 THR A N 1 ATOM 1297 C CA . THR A 1 166 ? -8.702 43.510 14.694 1.00 15.80 ? 199 THR A CA 1 ATOM 1298 C C . THR A 1 166 ? -8.025 43.784 16.055 1.00 15.72 ? 199 THR A C 1 ATOM 1299 O O . THR A 1 166 ? -8.557 44.500 16.846 1.00 15.79 ? 199 THR A O 1 ATOM 1300 C CB . THR A 1 166 ? -9.977 42.748 15.048 1.00 16.04 ? 199 THR A CB 1 ATOM 1301 O OG1 . THR A 1 166 ? -9.604 41.496 15.617 1.00 17.27 ? 199 THR A OG1 1 ATOM 1302 C CG2 . THR A 1 166 ? -10.809 42.446 13.834 1.00 15.95 ? 199 THR A CG2 1 ATOM 1303 N N . ASN A 1 167 ? -6.882 43.176 16.338 1.00 15.81 ? 200 ASN A N 1 ATOM 1304 C CA . ASN A 1 167 ? -6.204 43.375 17.607 1.00 15.51 ? 200 ASN A CA 1 ATOM 1305 C C . ASN A 1 167 ? -4.706 43.293 17.383 1.00 15.24 ? 200 ASN A C 1 ATOM 1306 O O . ASN A 1 167 ? -4.070 42.367 17.848 1.00 15.92 ? 200 ASN A O 1 ATOM 1307 C CB . ASN A 1 167 ? -6.652 42.311 18.572 1.00 15.27 ? 200 ASN A CB 1 ATOM 1308 C CG . ASN A 1 167 ? -8.078 42.510 19.005 1.00 16.24 ? 200 ASN A CG 1 ATOM 1309 O OD1 . ASN A 1 167 ? -8.333 43.240 19.957 1.00 18.33 ? 200 ASN A OD1 1 ATOM 1310 N ND2 . ASN A 1 167 ? -9.015 41.888 18.317 1.00 15.29 ? 200 ASN A ND2 1 ATOM 1311 N N . PRO A 1 168 ? -4.125 44.270 16.672 1.00 14.43 ? 201 PRO A N 1 ATOM 1312 C CA . PRO A 1 168 ? -2.768 44.089 16.111 1.00 14.10 ? 201 PRO A CA 1 ATOM 1313 C C . PRO A 1 168 ? -1.609 43.920 17.117 1.00 13.48 ? 201 PRO A C 1 ATOM 1314 O O . PRO A 1 168 ? -0.500 43.601 16.703 1.00 13.72 ? 201 PRO A O 1 ATOM 1315 C CB . PRO A 1 168 ? -2.564 45.341 15.244 1.00 14.15 ? 201 PRO A CB 1 ATOM 1316 C CG . PRO A 1 168 ? -3.923 45.931 15.119 1.00 14.84 ? 201 PRO A CG 1 ATOM 1317 C CD . PRO A 1 168 ? -4.673 45.594 16.368 1.00 14.19 ? 201 PRO A CD 1 ATOM 1318 N N . ASN A 1 169 ? -1.863 44.167 18.401 1.00 12.64 ? 202 ASN A N 1 ATOM 1319 C CA . ASN A 1 169 ? -0.923 43.782 19.462 1.00 12.39 ? 202 ASN A CA 1 ATOM 1320 C C . ASN A 1 169 ? -1.172 42.358 20.006 1.00 11.32 ? 202 ASN A C 1 ATOM 1321 O O . ASN A 1 169 ? -0.565 41.970 20.991 1.00 11.58 ? 202 ASN A O 1 ATOM 1322 C CB . ASN A 1 169 ? -0.920 44.799 20.607 1.00 12.49 ? 202 ASN A CB 1 ATOM 1323 C CG . ASN A 1 169 ? -2.320 45.032 21.187 1.00 13.55 ? 202 ASN A CG 1 ATOM 1324 O OD1 . ASN A 1 169 ? -3.338 44.585 20.632 1.00 14.05 ? 202 ASN A OD1 1 ATOM 1325 N ND2 . ASN A 1 169 ? -2.377 45.788 22.282 1.00 14.13 ? 202 ASN A ND2 1 ATOM 1326 N N . LEU A 1 170 ? -2.065 41.605 19.391 1.00 9.86 ? 203 LEU A N 1 ATOM 1327 C CA . LEU A 1 170 ? -2.156 40.196 19.657 1.00 9.31 ? 203 LEU A CA 1 ATOM 1328 C C . LEU A 1 170 ? -1.558 39.452 18.494 1.00 9.06 ? 203 LEU A C 1 ATOM 1329 O O . LEU A 1 170 ? -1.947 39.620 17.361 1.00 8.74 ? 203 LEU A O 1 ATOM 1330 C CB . LEU A 1 170 ? -3.598 39.793 19.832 1.00 9.34 ? 203 LEU A CB 1 ATOM 1331 C CG . LEU A 1 170 ? -3.918 38.291 19.991 1.00 9.17 ? 203 LEU A CG 1 ATOM 1332 C CD1 . LEU A 1 170 ? -3.263 37.779 21.271 1.00 9.33 ? 203 LEU A CD1 1 ATOM 1333 C CD2 . LEU A 1 170 ? -5.424 38.027 20.038 1.00 8.86 ? 203 LEU A CD2 1 ATOM 1334 N N . ARG A 1 171 ? -0.588 38.622 18.781 1.00 9.29 ? 204 ARG A N 1 ATOM 1335 C CA . ARG A 1 171 ? 0.074 37.853 17.746 1.00 9.31 ? 204 ARG A CA 1 ATOM 1336 C C . ARG A 1 171 ? -0.223 36.375 17.955 1.00 8.89 ? 204 ARG A C 1 ATOM 1337 O O . ARG A 1 171 ? 0.008 35.868 19.064 1.00 9.07 ? 204 ARG A O 1 ATOM 1338 C CB . ARG A 1 171 ? 1.577 38.032 17.860 1.00 9.58 ? 204 ARG A CB 1 ATOM 1339 C CG . ARG A 1 171 ? 2.366 37.216 16.848 1.00 9.92 ? 204 ARG A CG 1 ATOM 1340 C CD . ARG A 1 171 ? 3.837 37.359 17.145 1.00 10.43 ? 204 ARG A CD 1 ATOM 1341 N NE . ARG A 1 171 ? 4.226 38.739 16.898 1.00 10.68 ? 204 ARG A NE 1 ATOM 1342 C CZ . ARG A 1 171 ? 4.486 39.248 15.704 1.00 10.68 ? 204 ARG A CZ 1 ATOM 1343 N NH1 . ARG A 1 171 ? 4.472 38.510 14.606 1.00 10.44 1 204 ARG A NH1 1 ATOM 1344 N NH2 . ARG A 1 171 ? 4.832 40.506 15.637 1.00 11.18 ? 204 ARG A NH2 1 ATOM 1345 N N . ILE A 1 172 ? -0.690 35.705 16.899 1.00 7.82 ? 205 ILE A N 1 ATOM 1346 C CA . ILE A 1 172 ? -0.872 34.259 16.888 1.00 7.24 ? 205 ILE A CA 1 ATOM 1347 C C . ILE A 1 172 ? 0.401 33.606 16.377 1.00 7.30 ? 205 ILE A C 1 ATOM 1348 O O . ILE A 1 172 ? 0.907 33.995 15.319 1.00 7.36 ? 205 ILE A O 1 ATOM 1349 C CB . ILE A 1 172 ? -1.967 33.888 15.895 1.00 7.03 ? 205 ILE A CB 1 ATOM 1350 C CG1 . ILE A 1 172 ? -3.285 34.624 16.195 1.00 7.00 ? 205 ILE A CG1 1 ATOM 1351 C CG2 . ILE A 1 172 ? -2.214 32.405 15.889 1.00 7.16 ? 205 ILE A CG2 1 ATOM 1352 C CD1 . ILE A 1 172 ? -3.831 34.446 17.589 1.00 7.02 ? 205 ILE A CD1 1 ATOM 1353 N N . ILE A 1 173 ? 0.923 32.620 17.101 1.00 7.15 ? 206 ILE A N 1 ATOM 1354 C CA . ILE A 1 173 ? 2.077 31.847 16.656 1.00 6.96 ? 206 ILE A CA 1 ATOM 1355 C C . ILE A 1 173 ? 1.584 30.447 16.328 1.00 7.02 ? 206 ILE A C 1 ATOM 1356 O O . ILE A 1 173 ? 1.108 29.755 17.226 1.00 7.00 ? 206 ILE A O 1 ATOM 1357 C CB . ILE A 1 173 ? 3.122 31.751 17.772 1.00 6.94 ? 206 ILE A CB 1 ATOM 1358 C CG1 . ILE A 1 173 ? 3.667 33.144 18.089 1.00 6.85 ? 206 ILE A CG1 1 ATOM 1359 C CG2 . ILE A 1 173 ? 4.255 30.790 17.396 1.00 6.99 ? 206 ILE A CG2 1 ATOM 1360 C CD1 . ILE A 1 173 ? 4.751 33.175 19.134 1.00 6.69 ? 206 ILE A CD1 1 ATOM 1361 N N . SER A 1 174 ? 1.703 30.032 15.065 1.00 6.89 ? 207 SER A N 1 ATOM 1362 C CA . SER A 1 174 ? 1.119 28.769 14.606 1.00 7.02 ? 207 SER A CA 1 ATOM 1363 C C . SER A 1 174 ? 2.245 27.794 14.409 1.00 7.28 ? 207 SER A C 1 ATOM 1364 O O . SER A 1 174 ? 2.973 27.917 13.485 1.00 7.77 ? 207 SER A O 1 ATOM 1365 C CB . SER A 1 174 ? 0.368 28.965 13.287 1.00 7.04 ? 207 SER A CB 1 ATOM 1366 O OG . SER A 1 174 ? -0.245 27.786 12.819 1.00 6.63 ? 207 SER A OG 1 ATOM 1367 N N . LEU A 1 175 ? 2.422 26.869 15.325 1.00 7.56 ? 208 LEU A N 1 ATOM 1368 C CA . LEU A 1 175 ? 3.494 25.964 15.267 1.00 8.03 ? 208 LEU A CA 1 ATOM 1369 C C . LEU A 1 175 ? 3.147 24.719 14.468 1.00 8.68 ? 208 LEU A C 1 ATOM 1370 O O . LEU A 1 175 ? 1.998 24.313 14.395 1.00 9.42 ? 208 LEU A O 1 ATOM 1371 C CB . LEU A 1 175 ? 3.915 25.507 16.676 1.00 8.08 ? 208 LEU A CB 1 ATOM 1372 C CG . LEU A 1 175 ? 4.411 26.568 17.642 1.00 7.92 ? 208 LEU A CG 1 ATOM 1373 C CD1 . LEU A 1 175 ? 4.667 25.935 18.989 1.00 7.68 ? 208 LEU A CD1 1 ATOM 1374 C CD2 . LEU A 1 175 ? 5.638 27.220 17.104 1.00 7.80 ? 208 LEU A CD2 1 ATOM 1375 N N . ASN A 1 176 ? 4.199 24.086 13.934 1.00 9.27 ? 209 ASN A N 1 ATOM 1376 C CA . ASN A 1 176 ? 4.162 22.748 13.343 1.00 9.22 ? 209 ASN A CA 1 ATOM 1377 C C . ASN A 1 176 ? 4.716 21.799 14.360 1.00 8.83 ? 209 ASN A C 1 ATOM 1378 O O . ASN A 1 176 ? 5.893 21.494 14.356 1.00 8.96 ? 209 ASN A O 1 ATOM 1379 C CB . ASN A 1 176 ? 5.003 22.678 12.075 1.00 9.44 ? 209 ASN A CB 1 ATOM 1380 C CG . ASN A 1 176 ? 4.757 21.403 11.264 1.00 9.71 ? 209 ASN A CG 1 ATOM 1381 O OD1 . ASN A 1 176 ? 4.095 20.472 11.708 1.00 9.50 ? 209 ASN A OD1 1 ATOM 1382 N ND2 . ASN A 1 176 ? 5.272 21.390 10.027 1.00 10.03 ? 209 ASN A ND2 1 ATOM 1383 N N . THR A 1 177 ? 3.854 21.328 15.239 1.00 8.43 ? 210 THR A N 1 ATOM 1384 C CA . THR A 1 177 ? 4.307 20.424 16.248 1.00 8.28 ? 210 THR A CA 1 ATOM 1385 C C . THR A 1 177 ? 4.399 19.051 15.637 1.00 8.73 ? 210 THR A C 1 ATOM 1386 O O . THR A 1 177 ? 4.915 18.133 16.263 1.00 9.02 ? 210 THR A O 1 ATOM 1387 C CB . THR A 1 177 ? 3.405 20.439 17.499 1.00 8.05 ? 210 THR A CB 1 ATOM 1388 O OG1 . THR A 1 177 ? 2.015 20.391 17.153 1.00 8.05 ? 210 THR A OG1 1 ATOM 1389 C CG2 . THR A 1 177 ? 3.633 21.677 18.235 1.00 7.87 ? 210 THR A CG2 1 ATOM 1390 N N . ASN A 1 178 ? 3.923 18.902 14.401 1.00 8.83 ? 211 ASN A N 1 ATOM 1391 C CA . ASN A 1 178 ? 3.978 17.602 13.766 1.00 8.83 ? 211 ASN A CA 1 ATOM 1392 C C . ASN A 1 178 ? 5.446 17.228 13.615 1.00 9.22 ? 211 ASN A C 1 ATOM 1393 O O . ASN A 1 178 ? 5.822 16.071 13.679 1.00 9.56 ? 211 ASN A O 1 ATOM 1394 C CB . ASN A 1 178 ? 3.244 17.626 12.435 1.00 8.49 ? 211 ASN A CB 1 ATOM 1395 C CG . ASN A 1 178 ? 1.803 18.055 12.589 1.00 8.19 ? 211 ASN A CG 1 ATOM 1396 O OD1 . ASN A 1 178 ? 1.421 19.139 12.223 1.00 8.03 ? 211 ASN A OD1 1 ATOM 1397 N ND2 . ASN A 1 178 ? 1.025 17.223 13.205 1.00 8.24 ? 211 ASN A ND2 1 ATOM 1398 N N . LEU A 1 179 ? 6.288 18.230 13.517 1.00 9.39 ? 212 LEU A N 1 ATOM 1399 C CA . LEU A 1 179 ? 7.695 17.991 13.460 1.00 9.65 ? 212 LEU A CA 1 ATOM 1400 C C . LEU A 1 179 ? 8.186 17.187 14.663 1.00 10.04 ? 212 LEU A C 1 ATOM 1401 O O . LEU A 1 179 ? 9.154 16.474 14.542 1.00 10.14 ? 212 LEU A O 1 ATOM 1402 C CB . LEU A 1 179 ? 8.439 19.321 13.422 1.00 9.64 ? 212 LEU A CB 1 ATOM 1403 C CG . LEU A 1 179 ? 8.195 20.138 12.196 1.00 10.25 ? 212 LEU A CG 1 ATOM 1404 C CD1 . LEU A 1 179 ? 9.017 21.434 12.296 1.00 10.75 ? 212 LEU A CD1 1 ATOM 1405 C CD2 . LEU A 1 179 ? 8.593 19.347 10.958 1.00 10.28 ? 212 LEU A CD2 1 ATOM 1406 N N . TYR A 1 180 ? 7.541 17.338 15.812 1.00 10.53 ? 213 TYR A N 1 ATOM 1407 C CA . TYR A 1 180 ? 7.934 16.672 17.040 1.00 10.97 ? 213 TYR A CA 1 ATOM 1408 C C . TYR A 1 180 ? 7.171 15.388 17.392 1.00 10.61 ? 213 TYR A C 1 ATOM 1409 O O . TYR A 1 180 ? 7.419 14.775 18.420 1.00 10.82 ? 213 TYR A O 1 ATOM 1410 C CB . TYR A 1 180 ? 7.757 17.651 18.196 1.00 11.92 ? 213 TYR A CB 1 ATOM 1411 C CG . TYR A 1 180 ? 8.347 19.015 17.943 1.00 12.11 ? 213 TYR A CG 1 ATOM 1412 C CD1 . TYR A 1 180 ? 9.672 19.164 17.513 1.00 12.37 ? 213 TYR A CD1 1 ATOM 1413 C CD2 . TYR A 1 180 ? 7.592 20.160 18.126 1.00 11.93 ? 213 TYR A CD2 1 ATOM 1414 C CE1 . TYR A 1 180 ? 10.222 20.436 17.295 1.00 12.08 ? 213 TYR A CE1 1 ATOM 1415 C CE2 . TYR A 1 180 ? 8.128 21.429 17.869 1.00 12.19 ? 213 TYR A CE2 1 ATOM 1416 C CZ . TYR A 1 180 ? 9.442 21.554 17.477 1.00 11.95 ? 213 TYR A CZ 1 ATOM 1417 O OH . TYR A 1 180 ? 9.955 22.794 17.242 1.00 12.31 ? 213 TYR A OH 1 ATOM 1418 N N . TYR A 1 181 ? 6.263 14.971 16.532 1.00 10.66 ? 214 TYR A N 1 ATOM 1419 C CA . TYR A 1 181 ? 5.419 13.811 16.766 1.00 10.92 ? 214 TYR A CA 1 ATOM 1420 C C . TYR A 1 181 ? 6.143 12.465 16.555 1.00 11.97 ? 214 TYR A C 1 ATOM 1421 O O . TYR A 1 181 ? 6.820 12.249 15.528 1.00 12.61 ? 214 TYR A O 1 ATOM 1422 C CB . TYR A 1 181 ? 4.260 13.951 15.797 1.00 10.92 ? 214 TYR A CB 1 ATOM 1423 C CG . TYR A 1 181 ? 3.122 12.980 15.891 1.00 10.80 ? 214 TYR A CG 1 ATOM 1424 C CD1 . TYR A 1 181 ? 2.615 12.562 17.077 1.00 10.91 ? 214 TYR A CD1 1 ATOM 1425 C CD2 . TYR A 1 181 ? 2.530 12.529 14.745 1.00 11.64 ? 214 TYR A CD2 1 ATOM 1426 C CE1 . TYR A 1 181 ? 1.553 11.680 17.126 1.00 11.43 ? 214 TYR A CE1 1 ATOM 1427 C CE2 . TYR A 1 181 ? 1.483 11.639 14.760 1.00 11.78 ? 214 TYR A CE2 1 ATOM 1428 C CZ . TYR A 1 181 ? 0.997 11.222 15.950 1.00 11.82 ? 214 TYR A CZ 1 ATOM 1429 O OH . TYR A 1 181 ? -0.083 10.392 15.891 1.00 12.60 ? 214 TYR A OH 1 ATOM 1430 N N . GLY A 1 182 ? 5.965 11.562 17.512 1.00 12.88 ? 215 GLY A N 1 ATOM 1431 C CA . GLY A 1 182 ? 6.645 10.275 17.564 1.00 13.75 ? 215 GLY A CA 1 ATOM 1432 C C . GLY A 1 182 ? 6.891 9.594 16.246 1.00 15.38 ? 215 GLY A C 1 ATOM 1433 O O . GLY A 1 182 ? 8.032 9.330 15.893 1.00 18.43 ? 215 GLY A O 1 ATOM 1434 N N . PRO A 1 183 ? 5.839 9.346 15.475 1.00 15.74 ? 216 PRO A N 1 ATOM 1435 C CA . PRO A 1 183 ? 6.002 8.649 14.198 1.00 15.75 ? 216 PRO A CA 1 ATOM 1436 C C . PRO A 1 183 ? 6.679 9.378 13.064 1.00 17.12 ? 216 PRO A C 1 ATOM 1437 O O . PRO A 1 183 ? 6.776 8.793 11.943 1.00 19.84 ? 216 PRO A O 1 ATOM 1438 C CB . PRO A 1 183 ? 4.538 8.364 13.751 1.00 15.45 ? 216 PRO A CB 1 ATOM 1439 C CG . PRO A 1 183 ? 3.681 8.570 14.951 1.00 15.23 ? 216 PRO A CG 1 ATOM 1440 C CD . PRO A 1 183 ? 4.427 9.502 15.873 1.00 15.44 ? 216 PRO A CD 1 ATOM 1441 N N . ASN A 1 184 ? 7.068 10.639 13.260 1.00 17.52 ? 217 ASN A N 1 ATOM 1442 C CA . ASN A 1 184 ? 7.674 11.413 12.149 1.00 17.50 ? 217 ASN A CA 1 ATOM 1443 C C . ASN A 1 184 ? 9.149 11.037 11.968 1.00 18.33 ? 217 ASN A C 1 ATOM 1444 O O . ASN A 1 184 ? 10.004 11.480 12.708 1.00 16.22 ? 217 ASN A O 1 ATOM 1445 C CB . ASN A 1 184 ? 7.561 12.923 12.354 1.00 17.02 ? 217 ASN A CB 1 ATOM 1446 C CG . ASN A 1 184 ? 8.026 13.725 11.124 1.00 16.40 ? 217 ASN A CG 1 ATOM 1447 O OD1 . ASN A 1 184 ? 8.699 13.195 10.263 1.00 16.33 ? 217 ASN A OD1 1 ATOM 1448 N ND2 . ASN A 1 184 ? 7.643 14.996 11.042 1.00 15.93 ? 217 ASN A ND2 1 ATOM 1449 N N . ILE A 1 185 ? 9.411 10.226 10.954 1.00 20.00 ? 218 ILE A N 1 ATOM 1450 C CA . ILE A 1 185 ? 10.745 9.688 10.715 1.00 22.66 ? 218 ILE A CA 1 ATOM 1451 C C . ILE A 1 185 ? 11.690 10.762 10.175 1.00 22.55 ? 218 ILE A C 1 ATOM 1452 O O . ILE A 1 185 ? 12.900 10.603 10.278 1.00 25.58 ? 218 ILE A O 1 ATOM 1453 C CB . ILE A 1 185 ? 10.713 8.543 9.665 1.00 24.81 ? 218 ILE A CB 1 ATOM 1454 C CG1 . ILE A 1 185 ? 9.776 7.397 10.061 1.00 25.58 ? 218 ILE A CG1 1 ATOM 1455 C CG2 . ILE A 1 185 ? 12.069 7.951 9.456 1.00 26.31 ? 218 ILE A CG2 1 ATOM 1456 C CD1 . ILE A 1 185 ? 9.827 7.029 11.516 1.00 27.34 ? 218 ILE A CD1 1 ATOM 1457 N N . MET A 1 186 ? 11.157 11.843 9.610 1.00 20.25 ? 219 MET A N 1 ATOM 1458 C CA . MET A 1 186 ? 11.979 12.819 8.944 1.00 19.50 ? 219 MET A CA 1 ATOM 1459 C C . MET A 1 186 ? 12.759 13.677 9.897 1.00 20.29 ? 219 MET A C 1 ATOM 1460 O O . MET A 1 186 ? 13.710 14.340 9.500 1.00 21.19 ? 219 MET A O 1 ATOM 1461 C CB . MET A 1 186 ? 11.128 13.753 8.127 1.00 21.27 ? 219 MET A CB 1 ATOM 1462 C CG . MET A 1 186 ? 10.244 13.054 7.121 1.00 23.51 ? 219 MET A CG 1 ATOM 1463 S SD . MET A 1 186 ? 11.160 12.488 5.689 1.00 27.05 ? 219 MET A SD 1 ATOM 1464 C CE . MET A 1 186 ? 11.444 10.812 6.152 1.00 26.00 ? 219 MET A CE 1 ATOM 1465 N N . THR A 1 187 ? 12.337 13.740 11.150 1.00 20.29 ? 220 THR A N 1 ATOM 1466 C CA . THR A 1 187 ? 12.970 14.633 12.082 1.00 19.28 ? 220 THR A CA 1 ATOM 1467 C C . THR A 1 187 ? 13.816 13.872 13.090 1.00 20.68 ? 220 THR A C 1 ATOM 1468 O O . THR A 1 187 ? 14.405 14.473 13.976 1.00 20.53 ? 220 THR A O 1 ATOM 1469 C CB . THR A 1 187 ? 11.931 15.545 12.774 1.00 18.63 ? 220 THR A CB 1 ATOM 1470 O OG1 . THR A 1 187 ? 11.127 14.787 13.686 1.00 20.75 ? 220 THR A OG1 1 ATOM 1471 C CG2 . THR A 1 187 ? 11.057 16.178 11.755 1.00 17.77 ? 220 THR A CG2 1 ATOM 1472 N N . LEU A 1 188 ? 13.905 12.553 12.965 1.00 23.32 ? 221 LEU A N 1 ATOM 1473 C CA . LEU A 1 188 ? 14.708 11.783 13.927 1.00 26.01 ? 221 LEU A CA 1 ATOM 1474 C C . LEU A 1 188 ? 16.129 12.303 14.020 1.00 27.15 ? 221 LEU A C 1 ATOM 1475 O O . LEU A 1 188 ? 16.774 12.617 13.022 1.00 25.99 ? 221 LEU A O 1 ATOM 1476 C CB . LEU A 1 188 ? 14.760 10.307 13.549 1.00 27.36 ? 221 LEU A CB 1 ATOM 1477 C CG . LEU A 1 188 ? 13.558 9.561 14.078 1.00 28.29 ? 221 LEU A CG 1 ATOM 1478 C CD1 . LEU A 1 188 ? 13.388 8.316 13.256 1.00 31.40 ? 221 LEU A CD1 1 ATOM 1479 C CD2 . LEU A 1 188 ? 13.721 9.211 15.541 1.00 26.56 ? 221 LEU A CD2 1 ATOM 1480 N N . ASN A 1 189 ? 16.584 12.401 15.252 1.00 31.39 ? 222 ASN A N 1 ATOM 1481 C CA . ASN A 1 189 ? 17.919 12.842 15.606 1.00 34.03 ? 222 ASN A CA 1 ATOM 1482 C C . ASN A 1 189 ? 18.239 14.288 15.248 1.00 31.38 ? 222 ASN A C 1 ATOM 1483 O O . ASN A 1 189 ? 19.393 14.698 15.309 1.00 36.45 ? 222 ASN A O 1 ATOM 1484 C CB . ASN A 1 189 ? 18.976 11.876 15.042 1.00 38.82 ? 222 ASN A CB 1 ATOM 1485 C CG . ASN A 1 189 ? 20.120 11.676 16.006 1.00 47.33 ? 222 ASN A CG 1 ATOM 1486 O OD1 . ASN A 1 189 ? 19.895 11.409 17.194 1.00 52.41 ? 222 ASN A OD1 1 ATOM 1487 N ND2 . ASN A 1 189 ? 21.354 11.834 15.525 1.00 53.75 ? 222 ASN A ND2 1 ATOM 1488 N N . LYS A 1 190 ? 17.225 15.072 14.899 1.00 28.78 ? 223 LYS A N 1 ATOM 1489 C CA . LYS A 1 190 ? 17.376 16.543 14.756 1.00 25.42 ? 223 LYS A CA 1 ATOM 1490 C C . LYS A 1 190 ? 17.104 17.279 16.056 1.00 22.46 ? 223 LYS A C 1 ATOM 1491 O O . LYS A 1 190 ? 16.117 17.053 16.738 1.00 20.09 ? 223 LYS A O 1 ATOM 1492 C CB . LYS A 1 190 ? 16.459 17.092 13.685 1.00 23.87 ? 223 LYS A CB 1 ATOM 1493 C CG . LYS A 1 190 ? 16.861 16.636 12.319 1.00 23.80 ? 223 LYS A CG 1 ATOM 1494 C CD . LYS A 1 190 ? 15.934 17.253 11.326 1.00 26.15 ? 223 LYS A CD 1 ATOM 1495 C CE . LYS A 1 190 ? 16.109 16.682 9.934 1.00 27.59 ? 223 LYS A CE 1 ATOM 1496 N NZ . LYS A 1 190 ? 17.487 16.984 9.473 1.00 29.82 1 223 LYS A NZ 1 ATOM 1497 N N . THR A 1 191 ? 18.009 18.175 16.368 1.00 22.65 ? 224 THR A N 1 ATOM 1498 C CA . THR A 1 191 ? 17.971 18.906 17.608 1.00 23.66 ? 224 THR A CA 1 ATOM 1499 C C . THR A 1 191 ? 16.983 20.080 17.558 1.00 20.84 ? 224 THR A C 1 ATOM 1500 O O . THR A 1 191 ? 16.322 20.366 18.521 1.00 21.47 ? 224 THR A O 1 ATOM 1501 C CB . THR A 1 191 ? 19.365 19.417 17.967 1.00 26.08 ? 224 THR A CB 1 ATOM 1502 O OG1 . THR A 1 191 ? 19.288 20.045 19.233 1.00 31.41 ? 224 THR A OG1 1 ATOM 1503 C CG2 . THR A 1 191 ? 19.874 20.434 16.973 1.00 28.03 ? 224 THR A CG2 1 ATOM 1504 N N . ASP A 1 192 ? 16.873 20.731 16.419 1.00 18.71 ? 225 ASP A N 1 ATOM 1505 C CA . ASP A 1 192 ? 15.919 21.794 16.234 1.00 16.93 ? 225 ASP A CA 1 ATOM 1506 C C . ASP A 1 192 ? 15.338 21.724 14.811 1.00 15.20 ? 225 ASP A C 1 ATOM 1507 O O . ASP A 1 192 ? 15.665 22.517 13.965 1.00 15.46 ? 225 ASP A O 1 ATOM 1508 C CB . ASP A 1 192 ? 16.584 23.141 16.510 1.00 16.59 ? 225 ASP A CB 1 ATOM 1509 C CG . ASP A 1 192 ? 15.620 24.283 16.429 1.00 16.97 ? 225 ASP A CG 1 ATOM 1510 O OD1 . ASP A 1 192 ? 14.445 24.030 16.172 1.00 17.91 ? 225 ASP A OD1 1 ATOM 1511 O OD2 . ASP A 1 192 ? 16.007 25.450 16.580 1.00 17.94 -1 225 ASP A OD2 1 ATOM 1512 N N . PRO A 1 193 ? 14.445 20.781 14.557 1.00 14.01 ? 226 PRO A N 1 ATOM 1513 C CA . PRO A 1 193 ? 13.887 20.666 13.219 1.00 14.38 ? 226 PRO A CA 1 ATOM 1514 C C . PRO A 1 193 ? 13.190 21.919 12.663 1.00 14.13 ? 226 PRO A C 1 ATOM 1515 O O . PRO A 1 193 ? 12.338 22.546 13.312 1.00 14.16 ? 226 PRO A O 1 ATOM 1516 C CB . PRO A 1 193 ? 12.886 19.534 13.335 1.00 14.04 ? 226 PRO A CB 1 ATOM 1517 C CG . PRO A 1 193 ? 12.751 19.266 14.760 1.00 14.01 ? 226 PRO A CG 1 ATOM 1518 C CD . PRO A 1 193 ? 13.944 19.753 15.459 1.00 14.06 ? 226 PRO A CD 1 ATOM 1519 N N . ALA A 1 194 ? 13.603 22.252 11.458 1.00 13.50 ? 227 ALA A N 1 ATOM 1520 C CA . ALA A 1 194 ? 13.176 23.428 10.739 1.00 13.58 ? 227 ALA A CA 1 ATOM 1521 C C . ALA A 1 194 ? 13.544 24.705 11.460 1.00 14.15 ? 227 ALA A C 1 ATOM 1522 O O . ALA A 1 194 ? 13.072 25.759 11.100 1.00 14.27 ? 227 ALA A O 1 ATOM 1523 C CB . ALA A 1 194 ? 11.702 23.370 10.423 1.00 13.14 ? 227 ALA A CB 1 ATOM 1524 N N . ASN A 1 195 ? 14.412 24.616 12.443 1.00 15.70 ? 228 ASN A N 1 ATOM 1525 C CA . ASN A 1 195 ? 14.755 25.786 13.234 1.00 19.78 ? 228 ASN A CA 1 ATOM 1526 C C . ASN A 1 195 ? 13.607 26.404 14.096 1.00 18.82 ? 228 ASN A C 1 ATOM 1527 O O . ASN A 1 195 ? 13.634 27.572 14.525 1.00 17.99 ? 228 ASN A O 1 ATOM 1528 C CB . ASN A 1 195 ? 15.374 26.839 12.312 1.00 23.08 ? 228 ASN A CB 1 ATOM 1529 C CG . ASN A 1 195 ? 16.865 26.821 12.397 1.00 28.03 ? 228 ASN A CG 1 ATOM 1530 O OD1 . ASN A 1 195 ? 17.526 26.000 11.763 1.00 29.01 ? 228 ASN A OD1 1 ATOM 1531 N ND2 . ASN A 1 195 ? 17.412 27.688 13.257 1.00 34.30 ? 228 ASN A ND2 1 ATOM 1532 N N . GLN A 1 196 ? 12.595 25.601 14.351 1.00 16.54 ? 229 GLN A N 1 ATOM 1533 C CA . GLN A 1 196 ? 11.406 26.130 14.960 1.00 14.61 ? 229 GLN A CA 1 ATOM 1534 C C . GLN A 1 196 ? 11.709 26.616 16.315 1.00 13.31 ? 229 GLN A C 1 ATOM 1535 O O . GLN A 1 196 ? 11.172 27.579 16.717 1.00 12.99 ? 229 GLN A O 1 ATOM 1536 C CB . GLN A 1 196 ? 10.275 25.085 15.007 1.00 13.84 ? 229 GLN A CB 1 ATOM 1537 C CG . GLN A 1 196 ? 8.922 25.675 15.292 1.00 12.39 ? 229 GLN A CG 1 ATOM 1538 C CD . GLN A 1 196 ? 7.806 24.771 14.922 1.00 11.65 ? 229 GLN A CD 1 ATOM 1539 O OE1 . GLN A 1 196 ? 7.760 23.610 15.301 1.00 12.03 ? 229 GLN A OE1 1 ATOM 1540 N NE2 . GLN A 1 196 ? 6.877 25.298 14.222 1.00 11.29 ? 229 GLN A NE2 1 ATOM 1541 N N . PHE A 1 197 ? 12.568 25.955 17.034 1.00 14.04 ? 230 PHE A N 1 ATOM 1542 C CA . PHE A 1 197 ? 12.817 26.383 18.410 1.00 15.25 ? 230 PHE A CA 1 ATOM 1543 C C . PHE A 1 197 ? 13.459 27.728 18.423 1.00 17.64 ? 230 PHE A C 1 ATOM 1544 O O . PHE A 1 197 ? 13.046 28.587 19.172 1.00 20.27 ? 230 PHE A O 1 ATOM 1545 C CB . PHE A 1 197 ? 13.706 25.437 19.169 1.00 14.38 ? 230 PHE A CB 1 ATOM 1546 C CG . PHE A 1 197 ? 13.073 24.119 19.442 1.00 14.77 ? 230 PHE A CG 1 ATOM 1547 C CD1 . PHE A 1 197 ? 11.817 24.048 19.971 1.00 14.73 ? 230 PHE A CD1 1 ATOM 1548 C CD2 . PHE A 1 197 ? 13.737 22.955 19.182 1.00 15.57 ? 230 PHE A CD2 1 ATOM 1549 C CE1 . PHE A 1 197 ? 11.232 22.852 20.236 1.00 15.03 ? 230 PHE A CE1 1 ATOM 1550 C CE2 . PHE A 1 197 ? 13.152 21.737 19.451 1.00 15.82 ? 230 PHE A CE2 1 ATOM 1551 C CZ . PHE A 1 197 ? 11.888 21.690 19.950 1.00 15.60 ? 230 PHE A CZ 1 ATOM 1552 N N . GLU A 1 198 ? 14.464 27.918 17.587 1.00 19.71 ? 231 GLU A N 1 ATOM 1553 C CA . GLU A 1 198 ? 15.181 29.172 17.557 1.00 21.17 ? 231 GLU A CA 1 ATOM 1554 C C . GLU A 1 198 ? 14.282 30.283 17.071 1.00 18.19 ? 231 GLU A C 1 ATOM 1555 O O . GLU A 1 198 ? 14.267 31.355 17.613 1.00 17.69 ? 231 GLU A O 1 ATOM 1556 C CB . GLU A 1 198 ? 16.384 29.059 16.655 1.00 26.07 ? 231 GLU A CB 1 ATOM 1557 C CG . GLU A 1 198 ? 17.268 30.282 16.696 1.00 33.14 ? 231 GLU A CG 1 ATOM 1558 C CD . GLU A 1 198 ? 18.355 30.231 15.643 1.00 41.34 ? 231 GLU A CD 1 ATOM 1559 O OE1 . GLU A 1 198 ? 18.920 29.119 15.434 1.00 44.82 ? 231 GLU A OE1 1 ATOM 1560 O OE2 . GLU A 1 198 ? 18.630 31.308 15.040 1.00 47.47 -1 231 GLU A OE2 1 ATOM 1561 N N . TRP A 1 199 ? 13.522 30.013 16.039 1.00 16.51 ? 232 TRP A N 1 ATOM 1562 C CA . TRP A 1 199 ? 12.525 30.978 15.578 1.00 15.57 ? 232 TRP A CA 1 ATOM 1563 C C . TRP A 1 199 ? 11.434 31.282 16.619 1.00 15.32 ? 232 TRP A C 1 ATOM 1564 O O . TRP A 1 199 ? 11.004 32.443 16.710 1.00 14.17 ? 232 TRP A O 1 ATOM 1565 C CB . TRP A 1 199 ? 11.878 30.464 14.319 1.00 14.14 ? 232 TRP A CB 1 ATOM 1566 C CG . TRP A 1 199 ? 10.723 31.250 13.839 1.00 13.35 ? 232 TRP A CG 1 ATOM 1567 C CD1 . TRP A 1 199 ? 10.748 32.241 12.929 1.00 12.50 ? 232 TRP A CD1 1 ATOM 1568 C CD2 . TRP A 1 199 ? 9.339 31.032 14.160 1.00 12.90 ? 232 TRP A CD2 1 ATOM 1569 N NE1 . TRP A 1 199 ? 9.482 32.664 12.662 1.00 12.46 ? 232 TRP A NE1 1 ATOM 1570 C CE2 . TRP A 1 199 ? 8.596 31.943 13.409 1.00 12.11 ? 232 TRP A CE2 1 ATOM 1571 C CE3 . TRP A 1 199 ? 8.666 30.124 14.974 1.00 13.23 ? 232 TRP A CE3 1 ATOM 1572 C CZ2 . TRP A 1 199 ? 7.229 32.014 13.473 1.00 12.12 ? 232 TRP A CZ2 1 ATOM 1573 C CZ3 . TRP A 1 199 ? 7.280 30.197 15.034 1.00 12.77 ? 232 TRP A CZ3 1 ATOM 1574 C CH2 . TRP A 1 199 ? 6.589 31.155 14.314 1.00 12.46 ? 232 TRP A CH2 1 ATOM 1575 N N . LEU A 1 200 ? 11.011 30.252 17.371 1.00 14.73 ? 233 LEU A N 1 ATOM 1576 C CA . LEU A 1 200 ? 10.002 30.436 18.417 1.00 15.76 ? 233 LEU A CA 1 ATOM 1577 C C . LEU A 1 200 ? 10.503 31.391 19.517 1.00 16.92 ? 233 LEU A C 1 ATOM 1578 O O . LEU A 1 200 ? 9.820 32.377 19.848 1.00 16.46 ? 233 LEU A O 1 ATOM 1579 C CB . LEU A 1 200 ? 9.581 29.100 19.056 1.00 14.53 ? 233 LEU A CB 1 ATOM 1580 C CG . LEU A 1 200 ? 8.492 29.148 20.107 1.00 13.22 ? 233 LEU A CG 1 ATOM 1581 C CD1 . LEU A 1 200 ? 7.212 29.735 19.569 1.00 13.96 ? 233 LEU A CD1 1 ATOM 1582 C CD2 . LEU A 1 200 ? 8.201 27.795 20.607 1.00 12.81 ? 233 LEU A CD2 1 ATOM 1583 N N . GLU A 1 201 ? 11.689 31.105 20.058 1.00 18.09 ? 234 GLU A N 1 ATOM 1584 C CA . GLU A 1 201 ? 12.306 31.973 21.063 1.00 19.79 ? 234 GLU A CA 1 ATOM 1585 C C . GLU A 1 201 ? 12.460 33.378 20.569 1.00 18.87 ? 234 GLU A C 1 ATOM 1586 O O . GLU A 1 201 ? 12.128 34.348 21.208 1.00 19.23 ? 234 GLU A O 1 ATOM 1587 C CB . GLU A 1 201 ? 13.687 31.506 21.388 1.00 22.70 ? 234 GLU A CB 1 ATOM 1588 C CG . GLU A 1 201 ? 13.710 30.341 22.332 1.00 27.75 ? 234 GLU A CG 1 ATOM 1589 C CD . GLU A 1 201 ? 14.717 30.495 23.462 1.00 33.99 ? 234 GLU A CD 1 ATOM 1590 O OE1 . GLU A 1 201 ? 15.284 29.429 23.823 1.00 41.67 ? 234 GLU A OE1 1 ATOM 1591 O OE2 . GLU A 1 201 ? 14.908 31.641 24.010 1.00 36.56 -1 234 GLU A OE2 1 ATOM 1592 N N . SER A 1 202 ? 12.995 33.485 19.397 1.00 18.25 ? 235 SER A N 1 ATOM 1593 C CA . SER A 1 202 ? 13.232 34.785 18.863 1.00 18.69 ? 235 SER A CA 1 ATOM 1594 C C . SER A 1 202 ? 11.897 35.566 18.670 1.00 17.07 ? 235 SER A C 1 ATOM 1595 O O . SER A 1 202 ? 11.793 36.721 19.037 1.00 16.57 ? 235 SER A O 1 ATOM 1596 C CB . SER A 1 202 ? 14.101 34.632 17.614 1.00 19.05 ? 235 SER A CB 1 ATOM 1597 O OG . SER A 1 202 ? 13.771 35.606 16.690 1.00 24.19 ? 235 SER A OG 1 ATOM 1598 N N . THR A 1 203 ? 10.860 34.901 18.177 1.00 15.76 ? 236 THR A N 1 ATOM 1599 C CA . THR A 1 203 ? 9.554 35.510 18.052 1.00 14.58 ? 236 THR A CA 1 ATOM 1600 C C . THR A 1 203 ? 8.968 35.890 19.404 1.00 15.61 ? 236 THR A C 1 ATOM 1601 O O . THR A 1 203 ? 8.367 36.945 19.570 1.00 16.14 ? 236 THR A O 1 ATOM 1602 C CB . THR A 1 203 ? 8.597 34.549 17.394 1.00 14.03 ? 236 THR A CB 1 ATOM 1603 O OG1 . THR A 1 203 ? 9.121 34.149 16.133 1.00 13.29 ? 236 THR A OG1 1 ATOM 1604 C CG2 . THR A 1 203 ? 7.244 35.194 17.186 1.00 13.94 ? 236 THR A CG2 1 ATOM 1605 N N . LEU A 1 204 ? 9.128 35.031 20.392 1.00 16.46 ? 237 LEU A N 1 ATOM 1606 C CA . LEU A 1 204 ? 8.571 35.328 21.703 1.00 17.34 ? 237 LEU A CA 1 ATOM 1607 C C . LEU A 1 204 ? 9.277 36.505 22.356 1.00 18.90 ? 237 LEU A C 1 ATOM 1608 O O . LEU A 1 204 ? 8.643 37.299 22.990 1.00 17.69 ? 237 LEU A O 1 ATOM 1609 C CB . LEU A 1 204 ? 8.646 34.097 22.591 1.00 17.06 ? 237 LEU A CB 1 ATOM 1610 C CG . LEU A 1 204 ? 7.667 32.971 22.220 1.00 17.14 ? 237 LEU A CG 1 ATOM 1611 C CD1 . LEU A 1 204 ? 7.976 31.642 22.933 1.00 16.55 ? 237 LEU A CD1 1 ATOM 1612 C CD2 . LEU A 1 204 ? 6.264 33.454 22.529 1.00 17.23 ? 237 LEU A CD2 1 ATOM 1613 N N . ASN A 1 205 ? 10.595 36.584 22.199 1.00 22.56 ? 238 ASN A N 1 ATOM 1614 C CA . ASN A 1 205 ? 11.393 37.741 22.628 1.00 26.07 ? 238 ASN A CA 1 ATOM 1615 C C . ASN A 1 205 ? 10.903 39.027 21.972 1.00 25.00 ? 238 ASN A C 1 ATOM 1616 O O . ASN A 1 205 ? 10.643 40.008 22.654 1.00 25.91 ? 238 ASN A O 1 ATOM 1617 C CB . ASN A 1 205 ? 12.885 37.525 22.296 1.00 29.51 ? 238 ASN A CB 1 ATOM 1618 C CG . ASN A 1 205 ? 13.827 38.145 23.329 1.00 34.26 ? 238 ASN A CG 1 ATOM 1619 O OD1 . ASN A 1 205 ? 14.694 38.972 22.991 1.00 37.97 ? 238 ASN A OD1 1 ATOM 1620 N ND2 . ASN A 1 205 ? 13.686 37.727 24.596 1.00 35.27 ? 238 ASN A ND2 1 ATOM 1621 N N . ASN A 1 206 ? 10.747 39.011 20.655 1.00 25.40 ? 239 ASN A N 1 ATOM 1622 C CA . ASN A 1 206 ? 10.262 40.177 19.952 1.00 27.54 ? 239 ASN A CA 1 ATOM 1623 C C . ASN A 1 206 ? 8.935 40.620 20.547 1.00 25.47 ? 239 ASN A C 1 ATOM 1624 O O . ASN A 1 206 ? 8.715 41.784 20.810 1.00 25.81 ? 239 ASN A O 1 ATOM 1625 C CB . ASN A 1 206 ? 10.145 39.933 18.439 1.00 32.69 ? 239 ASN A CB 1 ATOM 1626 C CG . ASN A 1 206 ? 9.133 40.907 17.751 1.00 44.16 ? 239 ASN A CG 1 ATOM 1627 O OD1 . ASN A 1 206 ? 7.952 41.004 18.155 1.00 51.89 ? 239 ASN A OD1 1 ATOM 1628 N ND2 . ASN A 1 206 ? 9.581 41.613 16.690 1.00 45.90 ? 239 ASN A ND2 1 ATOM 1629 N N . SER A 1 207 ? 8.038 39.677 20.746 1.00 24.62 ? 240 SER A N 1 ATOM 1630 C CA . SER A 1 207 ? 6.717 39.990 21.240 1.00 23.00 ? 240 SER A CA 1 ATOM 1631 C C . SER A 1 207 ? 6.777 40.678 22.588 1.00 23.22 ? 240 SER A C 1 ATOM 1632 O O . SER A 1 207 ? 6.114 41.673 22.834 1.00 23.00 ? 240 SER A O 1 ATOM 1633 C CB . SER A 1 207 ? 5.905 38.709 21.372 1.00 21.30 ? 240 SER A CB 1 ATOM 1634 O OG . SER A 1 207 ? 5.414 38.341 20.125 1.00 19.56 ? 240 SER A OG 1 ATOM 1635 N N . GLN A 1 208 ? 7.582 40.122 23.452 1.00 24.69 ? 241 GLN A N 1 ATOM 1636 C CA . GLN A 1 208 ? 7.687 40.574 24.812 1.00 29.94 ? 241 GLN A CA 1 ATOM 1637 C C . GLN A 1 208 ? 8.173 41.990 24.877 1.00 33.18 ? 241 GLN A C 1 ATOM 1638 O O . GLN A 1 208 ? 7.843 42.711 25.808 1.00 35.95 ? 241 GLN A O 1 ATOM 1639 C CB . GLN A 1 208 ? 8.665 39.685 25.531 1.00 30.88 ? 241 GLN A CB 1 ATOM 1640 C CG . GLN A 1 208 ? 8.740 39.875 27.003 1.00 34.66 ? 241 GLN A CG 1 ATOM 1641 C CD . GLN A 1 208 ? 9.532 38.734 27.630 1.00 39.49 ? 241 GLN A CD 1 ATOM 1642 O OE1 . GLN A 1 208 ? 8.961 37.763 28.170 1.00 40.68 ? 241 GLN A OE1 1 ATOM 1643 N NE2 . GLN A 1 208 ? 10.861 38.817 27.519 1.00 38.97 ? 241 GLN A NE2 1 ATOM 1644 N N . GLN A 1 209 ? 8.975 42.366 23.885 1.00 36.10 ? 242 GLN A N 1 ATOM 1645 C CA . GLN A 1 209 ? 9.599 43.682 23.832 1.00 38.57 ? 242 GLN A CA 1 ATOM 1646 C C . GLN A 1 209 ? 8.811 44.706 23.060 1.00 35.16 ? 242 GLN A C 1 ATOM 1647 O O . GLN A 1 209 ? 9.161 45.876 23.072 1.00 36.84 ? 242 GLN A O 1 ATOM 1648 C CB . GLN A 1 209 ? 10.970 43.555 23.194 1.00 42.77 ? 242 GLN A CB 1 ATOM 1649 C CG . GLN A 1 209 ? 11.938 42.753 24.036 1.00 47.91 ? 242 GLN A CG 1 ATOM 1650 C CD . GLN A 1 209 ? 13.257 42.572 23.326 1.00 60.52 ? 242 GLN A CD 1 ATOM 1651 O OE1 . GLN A 1 209 ? 13.359 42.796 22.104 1.00 61.66 ? 242 GLN A OE1 1 ATOM 1652 N NE2 . GLN A 1 209 ? 14.291 42.168 24.079 1.00 67.56 ? 242 GLN A NE2 1 ATOM 1653 N N . ASN A 1 210 ? 7.779 44.248 22.360 1.00 31.50 ? 243 ASN A N 1 ATOM 1654 C CA . ASN A 1 210 ? 6.934 45.092 21.558 1.00 28.60 ? 243 ASN A CA 1 ATOM 1655 C C . ASN A 1 210 ? 5.536 45.153 22.107 1.00 27.85 ? 243 ASN A C 1 ATOM 1656 O O . ASN A 1 210 ? 4.573 45.444 21.371 1.00 28.31 ? 243 ASN A O 1 ATOM 1657 C CB . ASN A 1 210 ? 6.913 44.568 20.156 1.00 30.30 ? 243 ASN A CB 1 ATOM 1658 C CG . ASN A 1 210 ? 8.280 44.531 19.548 1.00 34.70 ? 243 ASN A CG 1 ATOM 1659 O OD1 . ASN A 1 210 ? 9.286 44.814 20.198 1.00 42.51 ? 243 ASN A OD1 1 ATOM 1660 N ND2 . ASN A 1 210 ? 8.333 44.174 18.297 1.00 39.16 ? 243 ASN A ND2 1 ATOM 1661 N N . LYS A 1 211 ? 5.429 44.891 23.406 1.00 25.83 ? 244 LYS A N 1 ATOM 1662 C CA . LYS A 1 211 ? 4.175 44.977 24.109 1.00 25.62 ? 244 LYS A CA 1 ATOM 1663 C C . LYS A 1 211 ? 3.086 44.185 23.427 1.00 23.32 ? 244 LYS A C 1 ATOM 1664 O O . LYS A 1 211 ? 1.992 44.674 23.244 1.00 23.31 ? 244 LYS A O 1 ATOM 1665 C CB . LYS A 1 211 ? 3.728 46.409 24.173 1.00 28.93 ? 244 LYS A CB 1 ATOM 1666 C CG . LYS A 1 211 ? 4.815 47.423 24.480 1.00 33.04 ? 244 LYS A CG 1 ATOM 1667 C CD . LYS A 1 211 ? 4.135 48.699 24.996 1.00 35.36 ? 244 LYS A CD 1 ATOM 1668 C CE . LYS A 1 211 ? 4.630 49.945 24.300 1.00 37.38 ? 244 LYS A CE 1 ATOM 1669 N NZ . LYS A 1 211 ? 3.643 51.052 24.481 1.00 40.81 1 244 LYS A NZ 1 ATOM 1670 N N . GLU A 1 212 ? 3.409 42.977 23.013 1.00 21.44 ? 245 GLU A N 1 ATOM 1671 C CA . GLU A 1 212 ? 2.446 42.070 22.404 1.00 19.87 ? 245 GLU A CA 1 ATOM 1672 C C . GLU A 1 212 ? 2.076 40.945 23.360 1.00 18.09 ? 245 GLU A C 1 ATOM 1673 O O . GLU A 1 212 ? 2.853 40.605 24.241 1.00 19.64 ? 245 GLU A O 1 ATOM 1674 C CB . GLU A 1 212 ? 3.070 41.453 21.153 1.00 20.02 ? 245 GLU A CB 1 ATOM 1675 C CG . GLU A 1 212 ? 2.950 42.319 19.929 1.00 20.07 ? 245 GLU A CG 1 ATOM 1676 C CD . GLU A 1 212 ? 3.832 41.909 18.773 1.00 20.28 ? 245 GLU A CD 1 ATOM 1677 O OE1 . GLU A 1 212 ? 4.594 40.924 18.794 1.00 21.04 ? 245 GLU A OE1 1 ATOM 1678 O OE2 . GLU A 1 212 ? 3.749 42.625 17.792 1.00 23.08 -1 245 GLU A OE2 1 ATOM 1679 N N . LYS A 1 213 ? 0.886 40.400 23.191 1.00 16.33 ? 246 LYS A N 1 ATOM 1680 C CA . LYS A 1 213 ? 0.542 39.093 23.701 1.00 15.33 ? 246 LYS A CA 1 ATOM 1681 C C . LYS A 1 213 ? 0.492 38.092 22.566 1.00 12.78 ? 246 LYS A C 1 ATOM 1682 O O . LYS A 1 213 ? 0.255 38.455 21.396 1.00 11.17 ? 246 LYS A O 1 ATOM 1683 C CB . LYS A 1 213 ? -0.843 39.084 24.311 1.00 16.95 ? 246 LYS A CB 1 ATOM 1684 C CG . LYS A 1 213 ? -1.125 40.231 25.224 1.00 19.42 ? 246 LYS A CG 1 ATOM 1685 C CD . LYS A 1 213 ? -0.112 40.310 26.338 1.00 21.09 ? 246 LYS A CD 1 ATOM 1686 C CE . LYS A 1 213 ? -0.369 39.240 27.362 1.00 22.72 ? 246 LYS A CE 1 ATOM 1687 N NZ . LYS A 1 213 ? 0.468 39.597 28.535 1.00 25.03 1 246 LYS A NZ 1 ATOM 1688 N N . VAL A 1 214 ? 0.611 36.830 22.970 1.00 10.56 ? 247 VAL A N 1 ATOM 1689 C CA . VAL A 1 214 ? 0.683 35.708 22.076 1.00 9.39 ? 247 VAL A CA 1 ATOM 1690 C C . VAL A 1 214 ? -0.299 34.632 22.477 1.00 8.95 ? 247 VAL A C 1 ATOM 1691 O O . VAL A 1 214 ? -0.436 34.292 23.640 1.00 8.44 ? 247 VAL A O 1 ATOM 1692 C CB . VAL A 1 214 ? 2.074 35.105 22.129 1.00 9.41 ? 247 VAL A CB 1 ATOM 1693 C CG1 . VAL A 1 214 ? 2.137 33.764 21.417 1.00 9.36 ? 247 VAL A CG1 1 ATOM 1694 C CG2 . VAL A 1 214 ? 3.066 36.062 21.487 1.00 9.54 ? 247 VAL A CG2 1 ATOM 1695 N N . TYR A 1 215 ? -1.014 34.126 21.481 1.00 8.73 ? 248 TYR A N 1 ATOM 1696 C CA . TYR A 1 215 ? -1.731 32.861 21.562 1.00 8.23 ? 248 TYR A CA 1 ATOM 1697 C C . TYR A 1 215 ? -0.933 31.881 20.755 1.00 8.24 ? 248 TYR A C 1 ATOM 1698 O O . TYR A 1 215 ? -0.611 32.124 19.601 1.00 9.18 ? 248 TYR A O 1 ATOM 1699 C CB . TYR A 1 215 ? -3.142 32.987 20.942 1.00 8.00 ? 248 TYR A CB 1 ATOM 1700 C CG . TYR A 1 215 ? -4.135 33.771 21.762 1.00 7.33 ? 248 TYR A CG 1 ATOM 1701 C CD1 . TYR A 1 215 ? -3.943 33.955 23.094 1.00 7.56 ? 248 TYR A CD1 1 ATOM 1702 C CD2 . TYR A 1 215 ? -5.269 34.277 21.205 1.00 7.09 ? 248 TYR A CD2 1 ATOM 1703 C CE1 . TYR A 1 215 ? -4.865 34.641 23.856 1.00 7.46 ? 248 TYR A CE1 1 ATOM 1704 C CE2 . TYR A 1 215 ? -6.188 34.991 21.934 1.00 6.92 ? 248 TYR A CE2 1 ATOM 1705 C CZ . TYR A 1 215 ? -5.961 35.174 23.261 1.00 7.10 ? 248 TYR A CZ 1 ATOM 1706 O OH . TYR A 1 215 ? -6.787 35.862 24.071 1.00 7.31 ? 248 TYR A OH 1 ATOM 1707 N N . ILE A 1 216 ? -0.565 30.785 21.364 1.00 8.13 ? 249 ILE A N 1 ATOM 1708 C CA . ILE A 1 216 ? 0.076 29.677 20.648 1.00 7.80 ? 249 ILE A CA 1 ATOM 1709 C C . ILE A 1 216 ? -0.966 28.715 20.116 1.00 7.59 ? 249 ILE A C 1 ATOM 1710 O O . ILE A 1 216 ? -1.880 28.362 20.824 1.00 7.55 ? 249 ILE A O 1 ATOM 1711 C CB . ILE A 1 216 ? 0.936 28.903 21.600 1.00 7.62 ? 249 ILE A CB 1 ATOM 1712 C CG1 . ILE A 1 216 ? 1.974 29.849 22.198 1.00 7.76 ? 249 ILE A CG1 1 ATOM 1713 C CG2 . ILE A 1 216 ? 1.559 27.713 20.917 1.00 7.58 ? 249 ILE A CG2 1 ATOM 1714 C CD1 . ILE A 1 216 ? 3.264 29.964 21.401 1.00 8.00 ? 249 ILE A CD1 1 ATOM 1715 N N . ILE A 1 217 ? -0.777 28.292 18.873 1.00 7.57 ? 250 ILE A N 1 ATOM 1716 C CA . ILE A 1 217 ? -1.704 27.463 18.067 1.00 7.39 ? 250 ILE A CA 1 ATOM 1717 C C . ILE A 1 217 ? -0.912 26.350 17.391 1.00 7.02 ? 250 ILE A C 1 ATOM 1718 O O . ILE A 1 217 ? 0.167 26.576 16.859 1.00 6.67 ? 250 ILE A O 1 ATOM 1719 C CB . ILE A 1 217 ? -2.440 28.391 17.098 1.00 7.84 ? 250 ILE A CB 1 ATOM 1720 C CG1 . ILE A 1 217 ? -3.824 28.378 17.493 1.00 8.40 ? 250 ILE A CG1 1 ATOM 1721 C CG2 . ILE A 1 217 ? -2.429 28.147 15.580 1.00 7.86 ? 250 ILE A CG2 1 ATOM 1722 C CD1 . ILE A 1 217 ? -3.956 29.380 18.560 1.00 9.25 ? 250 ILE A CD1 1 ATOM 1723 N N . ALA A 1 218 ? -1.411 25.118 17.494 1.00 6.67 ? 251 ALA A N 1 ATOM 1724 C CA . ALA A 1 218 ? -0.687 23.968 16.947 1.00 6.12 ? 251 ALA A CA 1 ATOM 1725 C C . ALA A 1 218 ? -1.558 22.756 16.916 1.00 5.64 ? 251 ALA A C 1 ATOM 1726 O O . ALA A 1 218 ? -2.657 22.791 17.441 1.00 5.36 ? 251 ALA A O 1 ATOM 1727 C CB . ALA A 1 218 ? 0.538 23.719 17.778 1.00 6.26 ? 251 ALA A CB 1 ATOM 1728 N N . HIS A 1 219 ? -1.086 21.689 16.278 1.00 5.42 ? 252 HIS A N 1 ATOM 1729 C CA . HIS A 1 219 ? -1.886 20.454 16.202 1.00 5.40 ? 252 HIS A CA 1 ATOM 1730 C C . HIS A 1 219 ? -1.637 19.448 17.336 1.00 5.62 ? 252 HIS A C 1 ATOM 1731 O O . HIS A 1 219 ? -2.428 19.289 18.202 1.00 5.60 ? 252 HIS A O 1 ATOM 1732 C CB . HIS A 1 219 ? -1.691 19.797 14.853 1.00 5.29 ? 252 HIS A CB 1 ATOM 1733 C CG . HIS A 1 219 ? -2.615 18.655 14.617 1.00 5.03 ? 252 HIS A CG 1 ATOM 1734 N ND1 . HIS A 1 219 ? -3.952 18.835 14.377 1.00 5.00 ? 252 HIS A ND1 1 ATOM 1735 C CD2 . HIS A 1 219 ? -2.405 17.324 14.587 1.00 4.95 ? 252 HIS A CD2 1 ATOM 1736 C CE1 . HIS A 1 219 ? -4.542 17.658 14.266 1.00 4.93 ? 252 HIS A CE1 1 ATOM 1737 N NE2 . HIS A 1 219 ? -3.620 16.725 14.379 1.00 4.93 ? 252 HIS A NE2 1 ATOM 1738 N N . VAL A 1 220 ? -0.521 18.759 17.316 1.00 6.10 ? 253 VAL A N 1 ATOM 1739 C CA . VAL A 1 220 ? -0.127 17.923 18.433 1.00 6.39 ? 253 VAL A CA 1 ATOM 1740 C C . VAL A 1 220 ? 0.191 18.745 19.657 1.00 6.65 ? 253 VAL A C 1 ATOM 1741 O O . VAL A 1 220 ? 1.039 19.622 19.563 1.00 6.97 ? 253 VAL A O 1 ATOM 1742 C CB . VAL A 1 220 ? 1.162 17.158 18.100 1.00 6.53 ? 253 VAL A CB 1 ATOM 1743 C CG1 . VAL A 1 220 ? 1.407 16.080 19.151 1.00 6.64 ? 253 VAL A CG1 1 ATOM 1744 C CG2 . VAL A 1 220 ? 0.978 16.459 16.769 1.00 6.65 ? 253 VAL A CG2 1 ATOM 1745 N N . PRO A 1 221 ? -0.442 18.448 20.808 1.00 6.82 ? 254 PRO A N 1 ATOM 1746 C CA . PRO A 1 221 ? -0.202 19.138 22.017 1.00 7.12 ? 254 PRO A CA 1 ATOM 1747 C C . PRO A 1 221 ? 1.050 18.725 22.712 1.00 7.68 ? 254 PRO A C 1 ATOM 1748 O O . PRO A 1 221 ? 1.543 17.669 22.480 1.00 7.71 ? 254 PRO A O 1 ATOM 1749 C CB . PRO A 1 221 ? -1.390 18.761 22.886 1.00 7.26 ? 254 PRO A CB 1 ATOM 1750 C CG . PRO A 1 221 ? -1.914 17.498 22.352 1.00 7.00 ? 254 PRO A CG 1 ATOM 1751 C CD . PRO A 1 221 ? -1.453 17.399 20.957 1.00 7.07 ? 254 PRO A CD 1 ATOM 1752 N N . VAL A 1 222 ? 1.555 19.588 23.584 1.00 8.61 ? 255 VAL A N 1 ATOM 1753 C CA . VAL A 1 222 ? 2.594 19.202 24.491 1.00 9.46 ? 255 VAL A CA 1 ATOM 1754 C C . VAL A 1 222 ? 2.018 18.309 25.577 1.00 10.63 ? 255 VAL A C 1 ATOM 1755 O O . VAL A 1 222 ? 0.792 18.147 25.661 1.00 12.29 ? 255 VAL A O 1 ATOM 1756 C CB . VAL A 1 222 ? 3.251 20.399 25.158 1.00 9.56 ? 255 VAL A CB 1 ATOM 1757 C CG1 . VAL A 1 222 ? 4.084 21.173 24.147 1.00 9.57 ? 255 VAL A CG1 1 ATOM 1758 C CG2 . VAL A 1 222 ? 2.228 21.282 25.820 1.00 9.43 ? 255 VAL A CG2 1 ATOM 1759 N N . GLY A 1 223 ? 2.876 17.697 26.391 1.00 10.82 ? 256 GLY A N 1 ATOM 1760 C CA . GLY A 1 223 ? 2.394 16.967 27.570 1.00 10.88 ? 256 GLY A CA 1 ATOM 1761 C C . GLY A 1 223 ? 2.031 15.514 27.350 1.00 11.08 ? 256 GLY A C 1 ATOM 1762 O O . GLY A 1 223 ? 2.265 14.958 26.328 1.00 10.19 ? 256 GLY A O 1 ATOM 1763 N N . TYR A 1 224 ? 1.415 14.930 28.363 1.00 13.32 ? 257 TYR A N 1 ATOM 1764 C CA . TYR A 1 224 ? 1.001 13.535 28.377 1.00 14.24 ? 257 TYR A CA 1 ATOM 1765 C C . TYR A 1 224 ? -0.443 13.316 27.964 1.00 15.19 ? 257 TYR A C 1 ATOM 1766 O O . TYR A 1 224 ? -1.328 14.105 28.267 1.00 14.16 ? 257 TYR A O 1 ATOM 1767 C CB . TYR A 1 224 ? 1.250 12.965 29.756 1.00 14.63 ? 257 TYR A CB 1 ATOM 1768 C CG . TYR A 1 224 ? 2.694 12.842 29.980 1.00 15.24 ? 257 TYR A CG 1 ATOM 1769 C CD1 . TYR A 1 224 ? 3.436 13.935 30.283 1.00 16.36 ? 257 TYR A CD1 1 ATOM 1770 C CD2 . TYR A 1 224 ? 3.354 11.634 29.758 1.00 17.21 ? 257 TYR A CD2 1 ATOM 1771 C CE1 . TYR A 1 224 ? 4.806 13.847 30.429 1.00 17.82 ? 257 TYR A CE1 1 ATOM 1772 C CE2 . TYR A 1 224 ? 4.731 11.531 29.899 1.00 17.32 ? 257 TYR A CE2 1 ATOM 1773 C CZ . TYR A 1 224 ? 5.435 12.651 30.242 1.00 17.47 ? 257 TYR A CZ 1 ATOM 1774 O OH . TYR A 1 224 ? 6.767 12.606 30.418 1.00 20.08 ? 257 TYR A OH 1 ATOM 1775 N N . LEU A 1 225 ? -0.642 12.242 27.206 1.00 18.26 ? 258 LEU A N 1 ATOM 1776 C CA . LEU A 1 225 ? -1.961 11.838 26.731 1.00 20.63 ? 258 LEU A CA 1 ATOM 1777 C C . LEU A 1 225 ? -2.810 11.393 27.906 1.00 22.05 ? 258 LEU A C 1 ATOM 1778 O O . LEU A 1 225 ? -2.374 10.560 28.690 1.00 23.59 ? 258 LEU A O 1 ATOM 1779 C CB . LEU A 1 225 ? -1.836 10.694 25.737 1.00 20.46 ? 258 LEU A CB 1 ATOM 1780 C CG . LEU A 1 225 ? -1.341 11.126 24.357 1.00 22.32 ? 258 LEU A CG 1 ATOM 1781 C CD1 . LEU A 1 225 ? -1.358 9.936 23.394 1.00 23.24 ? 258 LEU A CD1 1 ATOM 1782 C CD2 . LEU A 1 225 ? -2.137 12.298 23.751 1.00 22.35 ? 258 LEU A CD2 1 ATOM 1783 N N . PRO A 1 226 ? -4.030 11.932 28.037 1.00 23.84 ? 259 PRO A N 1 ATOM 1784 C CA . PRO A 1 226 ? -4.720 11.659 29.261 1.00 25.17 ? 259 PRO A CA 1 ATOM 1785 C C . PRO A 1 226 ? -5.238 10.261 29.439 1.00 26.33 ? 259 PRO A C 1 ATOM 1786 O O . PRO A 1 226 ? -5.661 9.948 30.524 1.00 27.96 ? 259 PRO A O 1 ATOM 1787 C CB . PRO A 1 226 ? -5.912 12.636 29.219 1.00 25.04 ? 259 PRO A CB 1 ATOM 1788 C CG . PRO A 1 226 ? -5.637 13.601 28.147 1.00 24.66 ? 259 PRO A CG 1 ATOM 1789 C CD . PRO A 1 226 ? -4.820 12.824 27.172 1.00 26.06 ? 259 PRO A CD 1 ATOM 1790 N N A SER A 1 227 ? -5.265 9.421 28.410 0.50 28.35 ? 260 SER A N 1 ATOM 1791 N N B SER A 1 227 ? -5.155 9.460 28.375 0.50 27.26 ? 260 SER A N 1 ATOM 1792 C CA A SER A 1 227 ? -5.805 8.058 28.579 0.50 29.39 ? 260 SER A CA 1 ATOM 1793 C CA B SER A 1 227 ? -5.714 8.108 28.271 0.50 27.47 ? 260 SER A CA 1 ATOM 1794 C C A SER A 1 227 ? -4.756 6.952 28.529 0.50 30.80 ? 260 SER A C 1 ATOM 1795 C C B SER A 1 227 ? -4.770 7.005 28.757 0.50 29.46 ? 260 SER A C 1 ATOM 1796 O O A SER A 1 227 ? -5.111 5.794 28.305 0.50 31.68 ? 260 SER A O 1 ATOM 1797 O O B SER A 1 227 ? -5.203 5.937 29.203 0.50 29.43 ? 260 SER A O 1 ATOM 1798 C CB A SER A 1 227 ? -6.935 7.769 27.570 0.50 29.19 ? 260 SER A CB 1 ATOM 1799 C CB B SER A 1 227 ? -6.088 7.845 26.798 0.50 26.71 ? 260 SER A CB 1 ATOM 1800 O OG A SER A 1 227 ? -8.204 8.184 28.077 0.50 28.80 ? 260 SER A OG 1 ATOM 1801 O OG B SER A 1 227 ? -5.166 8.440 25.877 0.50 23.46 ? 260 SER A OG 1 ATOM 1802 N N . SER A 1 228 ? -3.477 7.296 28.716 1.00 32.31 ? 261 SER A N 1 ATOM 1803 C CA . SER A 1 228 ? -2.419 6.277 28.823 1.00 34.58 ? 261 SER A CA 1 ATOM 1804 C C . SER A 1 228 ? -1.383 6.668 29.878 1.00 38.57 ? 261 SER A C 1 ATOM 1805 O O . SER A 1 228 ? -1.487 7.726 30.530 1.00 39.28 ? 261 SER A O 1 ATOM 1806 C CB . SER A 1 228 ? -1.738 6.102 27.461 1.00 36.35 ? 261 SER A CB 1 ATOM 1807 O OG . SER A 1 228 ? -2.676 6.078 26.374 1.00 40.63 ? 261 SER A OG 1 ATOM 1808 N N . GLN A 1 229 ? -0.368 5.825 30.032 1.00 39.58 ? 262 GLN A N 1 ATOM 1809 C CA . GLN A 1 229 ? 0.622 6.027 31.069 1.00 41.30 ? 262 GLN A CA 1 ATOM 1810 C C . GLN A 1 229 ? 1.978 6.272 30.458 1.00 35.71 ? 262 GLN A C 1 ATOM 1811 O O . GLN A 1 229 ? 2.460 5.487 29.685 1.00 35.26 ? 262 GLN A O 1 ATOM 1812 C CB . GLN A 1 229 ? 0.663 4.816 32.028 1.00 49.64 ? 262 GLN A CB 1 ATOM 1813 C CG . GLN A 1 229 ? 1.979 4.665 32.804 1.00 55.98 ? 262 GLN A CG 1 ATOM 1814 C CD . GLN A 1 229 ? 1.981 3.556 33.852 1.00 59.00 ? 262 GLN A CD 1 ATOM 1815 O OE1 . GLN A 1 229 ? 3.038 3.257 34.432 1.00 59.96 ? 262 GLN A OE1 1 ATOM 1816 N NE2 . GLN A 1 229 ? 0.816 2.944 34.104 1.00 55.59 ? 262 GLN A NE2 1 ATOM 1817 N N . ASN A 1 230 ? 2.578 7.384 30.835 1.00 35.26 ? 263 ASN A N 1 ATOM 1818 C CA . ASN A 1 230 ? 3.928 7.771 30.414 1.00 36.06 ? 263 ASN A CA 1 ATOM 1819 C C . ASN A 1 230 ? 4.100 7.889 28.882 1.00 32.81 ? 263 ASN A C 1 ATOM 1820 O O . ASN A 1 230 ? 5.229 7.840 28.395 1.00 36.09 ? 263 ASN A O 1 ATOM 1821 C CB . ASN A 1 230 ? 4.997 6.836 31.051 1.00 35.35 ? 263 ASN A CB 1 ATOM 1822 C CG . ASN A 1 230 ? 6.402 7.434 31.048 1.00 36.61 ? 263 ASN A CG 1 ATOM 1823 O OD1 . ASN A 1 230 ? 7.410 6.711 31.105 1.00 41.68 ? 263 ASN A OD1 1 ATOM 1824 N ND2 . ASN A 1 230 ? 6.487 8.750 30.947 1.00 37.24 ? 263 ASN A ND2 1 ATOM 1825 N N . ILE A 1 231 ? 2.999 8.080 28.155 1.00 27.77 ? 264 ILE A N 1 ATOM 1826 C CA . ILE A 1 231 ? 3.035 8.356 26.732 1.00 27.21 ? 264 ILE A CA 1 ATOM 1827 C C . ILE A 1 231 ? 2.777 9.838 26.430 1.00 25.24 ? 264 ILE A C 1 ATOM 1828 O O . ILE A 1 231 ? 1.651 10.291 26.585 1.00 24.20 ? 264 ILE A O 1 ATOM 1829 C CB . ILE A 1 231 ? 1.942 7.577 25.995 1.00 30.43 ? 264 ILE A CB 1 ATOM 1830 C CG1 . ILE A 1 231 ? 2.127 6.074 26.246 1.00 33.47 ? 264 ILE A CG1 1 ATOM 1831 C CG2 . ILE A 1 231 ? 1.968 7.899 24.504 1.00 28.43 ? 264 ILE A CG2 1 ATOM 1832 C CD1 . ILE A 1 231 ? 1.128 5.181 25.526 1.00 34.53 ? 264 ILE A CD1 1 ATOM 1833 N N . THR A 1 232 ? 3.809 10.564 25.985 1.00 22.39 ? 265 THR A N 1 ATOM 1834 C CA . THR A 1 232 ? 3.650 11.856 25.321 1.00 22.08 ? 265 THR A CA 1 ATOM 1835 C C . THR A 1 232 ? 3.426 11.675 23.802 1.00 23.59 ? 265 THR A C 1 ATOM 1836 O O . THR A 1 232 ? 3.943 10.730 23.198 1.00 28.45 ? 265 THR A O 1 ATOM 1837 C CB . THR A 1 232 ? 4.879 12.744 25.501 1.00 21.69 ? 265 THR A CB 1 ATOM 1838 O OG1 . THR A 1 232 ? 6.027 12.090 24.956 1.00 20.60 ? 265 THR A OG1 1 ATOM 1839 C CG2 . THR A 1 232 ? 5.142 13.041 26.976 1.00 22.23 ? 265 THR A CG2 1 ATOM 1840 N N . ALA A 1 233 ? 2.650 12.567 23.188 1.00 23.31 ? 266 ALA A N 1 ATOM 1841 C CA . ALA A 1 233 ? 2.462 12.552 21.735 1.00 22.22 ? 266 ALA A CA 1 ATOM 1842 C C . ALA A 1 233 ? 3.757 12.937 21.072 1.00 21.09 ? 266 ALA A C 1 ATOM 1843 O O . ALA A 1 233 ? 4.201 12.251 20.134 1.00 22.94 ? 266 ALA A O 1 ATOM 1844 C CB . ALA A 1 233 ? 1.399 13.536 21.320 1.00 23.03 ? 266 ALA A CB 1 ATOM 1845 N N . MET A 1 234 ? 4.360 14.025 21.547 1.00 18.37 ? 267 MET A N 1 ATOM 1846 C CA . MET A 1 234 ? 5.640 14.451 21.021 1.00 17.62 ? 267 MET A CA 1 ATOM 1847 C C . MET A 1 234 ? 6.687 13.570 21.628 1.00 17.63 ? 267 MET A C 1 ATOM 1848 O O . MET A 1 234 ? 6.457 13.041 22.710 1.00 17.24 ? 267 MET A O 1 ATOM 1849 C CB . MET A 1 234 ? 5.966 15.857 21.425 1.00 17.20 ? 267 MET A CB 1 ATOM 1850 C CG . MET A 1 234 ? 5.143 16.841 20.699 1.00 18.13 ? 267 MET A CG 1 ATOM 1851 S SD . MET A 1 234 ? 5.241 18.465 21.432 1.00 18.28 ? 267 MET A SD 1 ATOM 1852 C CE . MET A 1 234 ? 6.957 18.509 21.637 1.00 18.72 ? 267 MET A CE 1 ATOM 1853 N N . ARG A 1 235 ? 7.825 13.408 20.956 1.00 16.89 ? 268 ARG A N 1 ATOM 1854 C CA . ARG A 1 235 ? 8.950 12.751 21.606 1.00 17.57 ? 268 ARG A CA 1 ATOM 1855 C C . ARG A 1 235 ? 9.358 13.601 22.787 1.00 19.18 ? 268 ARG A C 1 ATOM 1856 O O . ARG A 1 235 ? 9.337 14.838 22.716 1.00 20.27 ? 268 ARG A O 1 ATOM 1857 C CB . ARG A 1 235 ? 10.123 12.587 20.665 1.00 17.44 ? 268 ARG A CB 1 ATOM 1858 C CG . ARG A 1 235 ? 9.872 11.634 19.505 1.00 17.17 ? 268 ARG A CG 1 ATOM 1859 C CD . ARG A 1 235 ? 11.117 11.509 18.610 1.00 17.76 ? 268 ARG A CD 1 ATOM 1860 N NE . ARG A 1 235 ? 10.691 11.316 17.246 1.00 17.46 ? 268 ARG A NE 1 ATOM 1861 C CZ . ARG A 1 235 ? 11.033 12.046 16.201 1.00 16.97 ? 268 ARG A CZ 1 ATOM 1862 N NH1 . ARG A 1 235 ? 11.908 13.010 16.283 1.00 17.17 1 268 ARG A NH1 1 ATOM 1863 N NH2 . ARG A 1 235 ? 10.498 11.750 15.034 1.00 17.63 ? 268 ARG A NH2 1 ATOM 1864 N N . GLU A 1 236 ? 9.694 12.931 23.876 1.00 20.86 ? 269 GLU A N 1 ATOM 1865 C CA . GLU A 1 236 ? 9.953 13.560 25.156 1.00 23.38 ? 269 GLU A CA 1 ATOM 1866 C C . GLU A 1 236 ? 10.928 14.693 25.071 1.00 22.61 ? 269 GLU A C 1 ATOM 1867 O O . GLU A 1 236 ? 10.742 15.733 25.735 1.00 20.61 ? 269 GLU A O 1 ATOM 1868 C CB . GLU A 1 236 ? 10.500 12.523 26.120 1.00 28.80 ? 269 GLU A CB 1 ATOM 1869 C CG . GLU A 1 236 ? 11.206 13.054 27.368 1.00 34.58 ? 269 GLU A CG 1 ATOM 1870 C CD . GLU A 1 236 ? 11.415 11.966 28.431 1.00 40.21 ? 269 GLU A CD 1 ATOM 1871 O OE1 . GLU A 1 236 ? 10.635 10.979 28.399 1.00 43.47 ? 269 GLU A OE1 1 ATOM 1872 O OE2 . GLU A 1 236 ? 12.329 12.094 29.307 1.00 43.45 -1 269 GLU A OE2 1 ATOM 1873 N N . TYR A 1 237 ? 11.964 14.500 24.254 1.00 22.25 ? 270 TYR A N 1 ATOM 1874 C CA . TYR A 1 237 ? 13.020 15.521 24.091 1.00 22.47 ? 270 TYR A CA 1 ATOM 1875 C C . TYR A 1 237 ? 12.448 16.842 23.620 1.00 19.89 ? 270 TYR A C 1 ATOM 1876 O O . TYR A 1 237 ? 12.756 17.859 24.174 1.00 20.66 ? 270 TYR A O 1 ATOM 1877 C CB . TYR A 1 237 ? 14.129 15.046 23.163 1.00 24.55 ? 270 TYR A CB 1 ATOM 1878 C CG . TYR A 1 237 ? 15.085 16.149 22.829 1.00 29.25 ? 270 TYR A CG 1 ATOM 1879 C CD1 . TYR A 1 237 ? 16.088 16.556 23.731 1.00 30.67 ? 270 TYR A CD1 1 ATOM 1880 C CD2 . TYR A 1 237 ? 14.995 16.800 21.607 1.00 31.15 ? 270 TYR A CD2 1 ATOM 1881 C CE1 . TYR A 1 237 ? 16.954 17.593 23.413 1.00 31.75 ? 270 TYR A CE1 1 ATOM 1882 C CE2 . TYR A 1 237 ? 15.847 17.840 21.277 1.00 33.42 ? 270 TYR A CE2 1 ATOM 1883 C CZ . TYR A 1 237 ? 16.817 18.243 22.172 1.00 35.63 ? 270 TYR A CZ 1 ATOM 1884 O OH . TYR A 1 237 ? 17.622 19.291 21.763 1.00 38.77 ? 270 TYR A OH 1 ATOM 1885 N N . TYR A 1 238 ? 11.567 16.822 22.643 1.00 17.74 ? 271 TYR A N 1 ATOM 1886 C CA . TYR A 1 238 ? 10.959 18.048 22.180 1.00 16.84 ? 271 TYR A CA 1 ATOM 1887 C C . TYR A 1 238 ? 9.846 18.554 23.123 1.00 15.77 ? 271 TYR A C 1 ATOM 1888 O O . TYR A 1 238 ? 9.591 19.755 23.230 1.00 15.30 ? 271 TYR A O 1 ATOM 1889 C CB . TYR A 1 238 ? 10.342 17.832 20.819 1.00 17.60 ? 271 TYR A CB 1 ATOM 1890 C CG . TYR A 1 238 ? 11.241 17.309 19.758 1.00 17.95 ? 271 TYR A CG 1 ATOM 1891 C CD1 . TYR A 1 238 ? 12.409 18.005 19.372 1.00 18.70 ? 271 TYR A CD1 1 ATOM 1892 C CD2 . TYR A 1 238 ? 10.889 16.176 19.056 1.00 17.78 ? 271 TYR A CD2 1 ATOM 1893 C CE1 . TYR A 1 238 ? 13.199 17.550 18.311 1.00 18.97 ? 271 TYR A CE1 1 ATOM 1894 C CE2 . TYR A 1 238 ? 11.666 15.712 17.997 1.00 18.02 ? 271 TYR A CE2 1 ATOM 1895 C CZ . TYR A 1 238 ? 12.810 16.393 17.631 1.00 18.65 ? 271 TYR A CZ 1 ATOM 1896 O OH . TYR A 1 238 ? 13.560 15.902 16.624 1.00 19.16 ? 271 TYR A OH 1 ATOM 1897 N N . ASN A 1 239 ? 9.149 17.655 23.783 1.00 14.59 ? 272 ASN A N 1 ATOM 1898 C CA . ASN A 1 239 ? 8.156 18.095 24.753 1.00 14.72 ? 272 ASN A CA 1 ATOM 1899 C C . ASN A 1 239 ? 8.853 18.939 25.803 1.00 16.48 ? 272 ASN A C 1 ATOM 1900 O O . ASN A 1 239 ? 8.472 20.077 26.021 1.00 16.83 ? 272 ASN A O 1 ATOM 1901 C CB . ASN A 1 239 ? 7.455 16.889 25.364 1.00 14.29 ? 272 ASN A CB 1 ATOM 1902 C CG . ASN A 1 239 ? 6.422 17.278 26.380 1.00 14.75 ? 272 ASN A CG 1 ATOM 1903 O OD1 . ASN A 1 239 ? 5.481 18.005 26.074 1.00 15.87 ? 272 ASN A OD1 1 ATOM 1904 N ND2 . ASN A 1 239 ? 6.596 16.834 27.604 1.00 14.29 ? 272 ASN A ND2 1 ATOM 1905 N N . GLU A 1 240 ? 9.917 18.394 26.406 1.00 18.57 ? 273 GLU A N 1 ATOM 1906 C CA . GLU A 1 240 ? 10.740 19.096 27.415 1.00 19.71 ? 273 GLU A CA 1 ATOM 1907 C C . GLU A 1 240 ? 11.307 20.446 26.912 1.00 19.74 ? 273 GLU A C 1 ATOM 1908 O O . GLU A 1 240 ? 11.368 21.406 27.643 1.00 19.04 ? 273 GLU A O 1 ATOM 1909 C CB . GLU A 1 240 ? 11.936 18.252 27.859 1.00 21.00 ? 273 GLU A CB 1 ATOM 1910 C CG . GLU A 1 240 ? 11.632 16.908 28.494 1.00 23.24 ? 273 GLU A CG 1 ATOM 1911 C CD . GLU A 1 240 ? 10.990 17.045 29.846 1.00 26.36 ? 273 GLU A CD 1 ATOM 1912 O OE1 . GLU A 1 240 ? 11.428 17.943 30.599 1.00 31.58 ? 273 GLU A OE1 1 ATOM 1913 O OE2 . GLU A 1 240 ? 10.048 16.263 30.160 1.00 26.77 -1 273 GLU A OE2 1 ATOM 1914 N N . LYS A 1 241 ? 11.737 20.520 25.673 1.00 20.82 ? 274 LYS A N 1 ATOM 1915 C CA . LYS A 1 241 ? 12.294 21.774 25.178 1.00 23.32 ? 274 LYS A CA 1 ATOM 1916 C C . LYS A 1 241 ? 11.201 22.819 25.039 1.00 20.20 ? 274 LYS A C 1 ATOM 1917 O O . LYS A 1 241 ? 11.413 23.957 25.376 1.00 18.35 ? 274 LYS A O 1 ATOM 1918 C CB . LYS A 1 241 ? 13.029 21.552 23.846 1.00 27.45 ? 274 LYS A CB 1 ATOM 1919 C CG . LYS A 1 241 ? 13.680 22.787 23.270 1.00 32.31 ? 274 LYS A CG 1 ATOM 1920 C CD . LYS A 1 241 ? 15.085 23.051 23.813 1.00 38.51 ? 274 LYS A CD 1 ATOM 1921 C CE . LYS A 1 241 ? 15.766 24.253 23.119 1.00 40.74 ? 274 LYS A CE 1 ATOM 1922 N NZ . LYS A 1 241 ? 16.351 25.228 24.088 1.00 41.87 1 274 LYS A NZ 1 ATOM 1923 N N . LEU A 1 242 ? 10.023 22.424 24.553 1.00 19.35 ? 275 LEU A N 1 ATOM 1924 C CA . LEU A 1 242 ? 8.931 23.385 24.377 1.00 17.83 ? 275 LEU A CA 1 ATOM 1925 C C . LEU A 1 242 ? 8.465 23.852 25.738 1.00 16.88 ? 275 LEU A C 1 ATOM 1926 O O . LEU A 1 242 ? 8.143 25.026 25.913 1.00 15.85 ? 275 LEU A O 1 ATOM 1927 C CB . LEU A 1 242 ? 7.752 22.787 23.627 1.00 17.64 ? 275 LEU A CB 1 ATOM 1928 C CG . LEU A 1 242 ? 7.700 22.800 22.122 1.00 18.45 ? 275 LEU A CG 1 ATOM 1929 C CD1 . LEU A 1 242 ? 6.421 22.092 21.623 1.00 19.06 ? 275 LEU A CD1 1 ATOM 1930 C CD2 . LEU A 1 242 ? 7.760 24.242 21.594 1.00 18.05 ? 275 LEU A CD2 1 ATOM 1931 N N . ILE A 1 243 ? 8.435 22.937 26.702 1.00 16.29 ? 276 ILE A N 1 ATOM 1932 C CA . ILE A 1 243 ? 7.993 23.287 28.049 1.00 17.15 ? 276 ILE A CA 1 ATOM 1933 C C . ILE A 1 243 ? 8.861 24.406 28.565 1.00 17.23 ? 276 ILE A C 1 ATOM 1934 O O . ILE A 1 243 ? 8.351 25.447 28.924 1.00 16.97 ? 276 ILE A O 1 ATOM 1935 C CB . ILE A 1 243 ? 8.012 22.076 29.047 1.00 17.62 ? 276 ILE A CB 1 ATOM 1936 C CG1 . ILE A 1 243 ? 6.947 21.039 28.726 1.00 18.44 ? 276 ILE A CG1 1 ATOM 1937 C CG2 . ILE A 1 243 ? 7.738 22.522 30.468 1.00 17.87 ? 276 ILE A CG2 1 ATOM 1938 C CD1 . ILE A 1 243 ? 5.616 21.646 28.335 1.00 18.81 ? 276 ILE A CD1 1 ATOM 1939 N N . ASP A 1 244 ? 10.169 24.197 28.567 1.00 18.42 ? 277 ASP A N 1 ATOM 1940 C CA . ASP A 1 244 ? 11.088 25.199 29.055 1.00 20.98 ? 277 ASP A CA 1 ATOM 1941 C C . ASP A 1 244 ? 10.954 26.508 28.328 1.00 17.36 ? 277 ASP A C 1 ATOM 1942 O O . ASP A 1 244 ? 10.964 27.519 28.983 1.00 17.34 ? 277 ASP A O 1 ATOM 1943 C CB . ASP A 1 244 ? 12.553 24.705 29.047 1.00 26.16 ? 277 ASP A CB 1 ATOM 1944 C CG . ASP A 1 244 ? 12.775 23.560 30.053 1.00 36.10 ? 277 ASP A CG 1 ATOM 1945 O OD1 . ASP A 1 244 ? 12.210 23.553 31.217 1.00 42.62 ? 277 ASP A OD1 1 ATOM 1946 O OD2 . ASP A 1 244 ? 13.496 22.614 29.661 1.00 45.77 -1 277 ASP A OD2 1 ATOM 1947 N N . ILE A 1 245 ? 10.817 26.511 27.001 1.00 15.24 ? 278 ILE A N 1 ATOM 1948 C CA . ILE A 1 245 ? 10.518 27.758 26.286 1.00 14.00 ? 278 ILE A CA 1 ATOM 1949 C C . ILE A 1 245 ? 9.215 28.421 26.717 1.00 13.17 ? 278 ILE A C 1 ATOM 1950 O O . ILE A 1 245 ? 9.181 29.611 26.934 1.00 13.07 ? 278 ILE A O 1 ATOM 1951 C CB . ILE A 1 245 ? 10.457 27.589 24.779 1.00 13.87 ? 278 ILE A CB 1 ATOM 1952 C CG1 . ILE A 1 245 ? 11.833 27.253 24.232 1.00 13.52 ? 278 ILE A CG1 1 ATOM 1953 C CG2 . ILE A 1 245 ? 9.990 28.877 24.115 1.00 13.62 ? 278 ILE A CG2 1 ATOM 1954 C CD1 . ILE A 1 245 ? 11.785 26.738 22.805 1.00 13.88 ? 278 ILE A CD1 1 ATOM 1955 N N . PHE A 1 246 ? 8.153 27.655 26.879 1.00 12.85 ? 279 PHE A N 1 ATOM 1956 C CA . PHE A 1 246 ? 6.881 28.224 27.346 1.00 12.60 ? 279 PHE A CA 1 ATOM 1957 C C . PHE A 1 246 ? 6.975 28.763 28.775 1.00 13.47 ? 279 PHE A C 1 ATOM 1958 O O . PHE A 1 246 ? 6.294 29.707 29.126 1.00 13.51 ? 279 PHE A O 1 ATOM 1959 C CB . PHE A 1 246 ? 5.733 27.205 27.227 1.00 11.78 ? 279 PHE A CB 1 ATOM 1960 C CG . PHE A 1 246 ? 5.365 26.804 25.788 1.00 10.52 ? 279 PHE A CG 1 ATOM 1961 C CD1 . PHE A 1 246 ? 5.523 27.673 24.721 1.00 10.15 ? 279 PHE A CD1 1 ATOM 1962 C CD2 . PHE A 1 246 ? 4.799 25.571 25.545 1.00 9.96 ? 279 PHE A CD2 1 ATOM 1963 C CE1 . PHE A 1 246 ? 5.167 27.324 23.433 1.00 9.73 ? 279 PHE A CE1 1 ATOM 1964 C CE2 . PHE A 1 246 ? 4.405 25.214 24.277 1.00 10.06 ? 279 PHE A CE2 1 ATOM 1965 C CZ . PHE A 1 246 ? 4.601 26.087 23.209 1.00 10.09 ? 279 PHE A CZ 1 ATOM 1966 N N . GLN A 1 247 ? 7.836 28.184 29.591 1.00 15.25 ? 280 GLN A N 1 ATOM 1967 C CA . GLN A 1 247 ? 8.075 28.700 30.952 1.00 16.53 ? 280 GLN A CA 1 ATOM 1968 C C . GLN A 1 247 ? 8.853 29.991 30.906 1.00 17.86 ? 280 GLN A C 1 ATOM 1969 O O . GLN A 1 247 ? 8.460 30.927 31.572 1.00 18.20 ? 280 GLN A O 1 ATOM 1970 C CB . GLN A 1 247 ? 8.844 27.702 31.789 1.00 16.85 ? 280 GLN A CB 1 ATOM 1971 C CG . GLN A 1 247 ? 8.027 26.448 32.042 1.00 18.18 ? 280 GLN A CG 1 ATOM 1972 C CD . GLN A 1 247 ? 8.794 25.367 32.761 1.00 18.66 ? 280 GLN A CD 1 ATOM 1973 O OE1 . GLN A 1 247 ? 9.980 25.096 32.455 1.00 20.77 ? 280 GLN A OE1 1 ATOM 1974 N NE2 . GLN A 1 247 ? 8.131 24.728 33.703 1.00 17.04 ? 280 GLN A NE2 1 ATOM 1975 N N . LYS A 1 248 ? 9.931 30.057 30.109 1.00 19.28 ? 281 LYS A N 1 ATOM 1976 C CA . LYS A 1 248 ? 10.661 31.308 29.933 1.00 20.48 ? 281 LYS A CA 1 ATOM 1977 C C . LYS A 1 248 ? 9.717 32.445 29.528 1.00 19.21 ? 281 LYS A C 1 ATOM 1978 O O . LYS A 1 248 ? 9.924 33.551 29.918 1.00 19.63 ? 281 LYS A O 1 ATOM 1979 C CB . LYS A 1 248 ? 11.750 31.194 28.874 1.00 25.27 ? 281 LYS A CB 1 ATOM 1980 C CG . LYS A 1 248 ? 12.983 30.364 29.214 1.00 31.36 ? 281 LYS A CG 1 ATOM 1981 C CD . LYS A 1 248 ? 14.162 30.662 28.240 1.00 38.78 ? 281 LYS A CD 1 ATOM 1982 C CE . LYS A 1 248 ? 14.967 29.424 27.734 1.00 41.96 ? 281 LYS A CE 1 ATOM 1983 N NZ . LYS A 1 248 ? 15.597 28.644 28.859 1.00 42.87 1 281 LYS A NZ 1 ATOM 1984 N N . TYR A 1 249 ? 8.683 32.183 28.745 1.00 18.01 ? 282 TYR A N 1 ATOM 1985 C CA . TYR A 1 249 ? 7.852 33.245 28.223 1.00 16.87 ? 282 TYR A CA 1 ATOM 1986 C C . TYR A 1 249 ? 6.405 33.158 28.643 1.00 16.61 ? 282 TYR A C 1 ATOM 1987 O O . TYR A 1 249 ? 5.507 33.712 27.957 1.00 16.85 ? 282 TYR A O 1 ATOM 1988 C CB . TYR A 1 249 ? 7.939 33.257 26.704 1.00 16.90 ? 282 TYR A CB 1 ATOM 1989 C CG . TYR A 1 249 ? 9.305 33.572 26.264 1.00 17.24 ? 282 TYR A CG 1 ATOM 1990 C CD1 . TYR A 1 249 ? 9.719 34.887 26.133 1.00 17.71 ? 282 TYR A CD1 1 ATOM 1991 C CD2 . TYR A 1 249 ? 10.222 32.570 26.061 1.00 17.40 ? 282 TYR A CD2 1 ATOM 1992 C CE1 . TYR A 1 249 ? 11.019 35.191 25.804 1.00 17.61 ? 282 TYR A CE1 1 ATOM 1993 C CE2 . TYR A 1 249 ? 11.511 32.860 25.695 1.00 17.67 ? 282 TYR A CE2 1 ATOM 1994 C CZ . TYR A 1 249 ? 11.909 34.176 25.584 1.00 17.93 ? 282 TYR A CZ 1 ATOM 1995 O OH . TYR A 1 249 ? 13.198 34.456 25.176 1.00 19.00 ? 282 TYR A OH 1 ATOM 1996 N N . SER A 1 250 ? 6.160 32.527 29.774 1.00 15.96 ? 283 SER A N 1 ATOM 1997 C CA . SER A 1 250 ? 4.799 32.444 30.274 1.00 16.97 ? 283 SER A CA 1 ATOM 1998 C C . SER A 1 250 ? 4.085 33.779 30.431 1.00 17.56 ? 283 SER A C 1 ATOM 1999 O O . SER A 1 250 ? 2.873 33.825 30.284 1.00 19.55 ? 283 SER A O 1 ATOM 2000 C CB . SER A 1 250 ? 4.719 31.668 31.588 1.00 17.61 ? 283 SER A CB 1 ATOM 2001 O OG . SER A 1 250 ? 5.232 32.399 32.687 1.00 17.59 ? 283 SER A OG 1 ATOM 2002 N N . ASP A 1 251 ? 4.813 34.852 30.701 1.00 18.06 ? 284 ASP A N 1 ATOM 2003 C CA . ASP A 1 251 ? 4.241 36.216 30.717 1.00 20.08 ? 284 ASP A CA 1 ATOM 2004 C C . ASP A 1 251 ? 3.577 36.639 29.405 1.00 17.78 ? 284 ASP A C 1 ATOM 2005 O O . ASP A 1 251 ? 2.412 37.007 29.386 1.00 16.67 ? 284 ASP A O 1 ATOM 2006 C CB . ASP A 1 251 ? 5.276 37.269 31.204 1.00 25.68 ? 284 ASP A CB 1 ATOM 2007 C CG . ASP A 1 251 ? 6.562 37.375 30.291 1.00 33.74 ? 284 ASP A CG 1 ATOM 2008 O OD1 . ASP A 1 251 ? 7.094 36.364 29.720 1.00 33.65 ? 284 ASP A OD1 1 ATOM 2009 O OD2 . ASP A 1 251 ? 7.066 38.527 30.161 1.00 45.89 -1 284 ASP A OD2 1 ATOM 2010 N N . VAL A 1 252 ? 4.291 36.531 28.288 1.00 16.64 ? 285 VAL A N 1 ATOM 2011 C CA . VAL A 1 252 ? 3.734 36.962 26.983 1.00 15.72 ? 285 VAL A CA 1 ATOM 2012 C C . VAL A 1 252 ? 2.580 36.103 26.455 1.00 13.60 ? 285 VAL A C 1 ATOM 2013 O O . VAL A 1 252 ? 1.758 36.607 25.725 1.00 12.89 ? 285 VAL A O 1 ATOM 2014 C CB . VAL A 1 252 ? 4.756 36.887 25.825 1.00 17.05 ? 285 VAL A CB 1 ATOM 2015 C CG1 . VAL A 1 252 ? 4.722 38.148 25.037 1.00 17.63 ? 285 VAL A CG1 1 ATOM 2016 C CG2 . VAL A 1 252 ? 6.160 36.666 26.305 1.00 19.54 ? 285 VAL A CG2 1 ATOM 2017 N N . ILE A 1 253 ? 2.638 34.792 26.712 1.00 11.77 ? 286 ILE A N 1 ATOM 2018 C CA . ILE A 1 253 ? 1.716 33.835 26.155 1.00 10.87 ? 286 ILE A CA 1 ATOM 2019 C C . ILE A 1 253 ? 0.497 33.908 27.046 1.00 10.19 ? 286 ILE A C 1 ATOM 2020 O O . ILE A 1 253 ? 0.593 33.804 28.237 1.00 11.08 ? 286 ILE A O 1 ATOM 2021 C CB . ILE A 1 253 ? 2.321 32.427 26.206 1.00 11.18 ? 286 ILE A CB 1 ATOM 2022 C CG1 . ILE A 1 253 ? 3.537 32.340 25.252 1.00 11.05 ? 286 ILE A CG1 1 ATOM 2023 C CG2 . ILE A 1 253 ? 1.289 31.368 25.816 1.00 11.46 ? 286 ILE A CG2 1 ATOM 2024 C CD1 . ILE A 1 253 ? 4.384 31.109 25.420 1.00 10.79 ? 286 ILE A CD1 1 ATOM 2025 N N . ALA A 1 254 ? -0.633 34.173 26.480 1.00 9.11 ? 287 ALA A N 1 ATOM 2026 C CA . ALA A 1 254 ? -1.818 34.350 27.223 1.00 8.67 ? 287 ALA A CA 1 ATOM 2027 C C . ALA A 1 254 ? -2.737 33.160 27.054 1.00 8.79 ? 287 ALA A C 1 ATOM 2028 O O . ALA A 1 254 ? -3.807 33.148 27.618 1.00 9.31 ? 287 ALA A O 1 ATOM 2029 C CB . ALA A 1 254 ? -2.521 35.606 26.737 1.00 8.41 ? 287 ALA A CB 1 ATOM 2030 N N . GLY A 1 255 ? -2.345 32.182 26.242 1.00 8.62 ? 288 GLY A N 1 ATOM 2031 C CA . GLY A 1 255 ? -3.144 30.975 26.020 1.00 8.31 ? 288 GLY A CA 1 ATOM 2032 C C . GLY A 1 255 ? -2.530 30.088 24.928 1.00 7.96 ? 288 GLY A C 1 ATOM 2033 O O . GLY A 1 255 ? -1.867 30.602 24.006 1.00 7.39 ? 288 GLY A O 1 ATOM 2034 N N . GLN A 1 256 ? -2.718 28.765 25.090 1.00 7.38 ? 289 GLN A N 1 ATOM 2035 C CA . GLN A 1 256 ? -2.331 27.774 24.099 1.00 7.02 ? 289 GLN A CA 1 ATOM 2036 C C . GLN A 1 256 ? -3.512 26.889 23.660 1.00 6.34 ? 289 GLN A C 1 ATOM 2037 O O . GLN A 1 256 ? -4.370 26.538 24.459 1.00 5.88 ? 289 GLN A O 1 ATOM 2038 C CB . GLN A 1 256 ? -1.226 26.909 24.649 1.00 7.44 ? 289 GLN A CB 1 ATOM 2039 C CG . GLN A 1 256 ? 0.037 27.662 24.939 1.00 7.94 ? 289 GLN A CG 1 ATOM 2040 C CD . GLN A 1 256 ? 1.091 26.792 25.582 1.00 8.38 ? 289 GLN A CD 1 ATOM 2041 O OE1 . GLN A 1 256 ? 1.325 25.661 25.144 1.00 8.96 ? 289 GLN A OE1 1 ATOM 2042 N NE2 . GLN A 1 256 ? 1.677 27.283 26.676 1.00 8.25 ? 289 GLN A NE2 1 ATOM 2043 N N . PHE A 1 257 ? -3.537 26.548 22.372 1.00 5.84 ? 290 PHE A N 1 ATOM 2044 C CA . PHE A 1 257 ? -4.667 25.851 21.784 1.00 5.65 ? 290 PHE A CA 1 ATOM 2045 C C . PHE A 1 257 ? -4.196 24.742 20.839 1.00 5.39 ? 290 PHE A C 1 ATOM 2046 O O . PHE A 1 257 ? -3.393 24.970 19.939 1.00 5.46 ? 290 PHE A O 1 ATOM 2047 C CB . PHE A 1 257 ? -5.601 26.840 21.075 1.00 5.72 ? 290 PHE A CB 1 ATOM 2048 C CG . PHE A 1 257 ? -5.902 28.047 21.881 1.00 5.88 ? 290 PHE A CG 1 ATOM 2049 C CD1 . PHE A 1 257 ? -6.979 28.077 22.713 1.00 6.07 ? 290 PHE A CD1 1 ATOM 2050 C CD2 . PHE A 1 257 ? -5.074 29.158 21.829 1.00 5.92 ? 290 PHE A CD2 1 ATOM 2051 C CE1 . PHE A 1 257 ? -7.243 29.208 23.485 1.00 6.27 ? 290 PHE A CE1 1 ATOM 2052 C CE2 . PHE A 1 257 ? -5.325 30.263 22.604 1.00 6.06 ? 290 PHE A CE2 1 ATOM 2053 C CZ . PHE A 1 257 ? -6.413 30.298 23.434 1.00 6.08 ? 290 PHE A CZ 1 ATOM 2054 N N . TYR A 1 258 ? -4.728 23.545 21.037 1.00 5.08 ? 291 TYR A N 1 ATOM 2055 C CA . TYR A 1 258 ? -4.246 22.342 20.366 1.00 4.82 ? 291 TYR A CA 1 ATOM 2056 C C . TYR A 1 258 ? -5.410 21.483 19.889 1.00 4.71 ? 291 TYR A C 1 ATOM 2057 O O . TYR A 1 258 ? -6.553 21.718 20.225 1.00 4.78 ? 291 TYR A O 1 ATOM 2058 C CB . TYR A 1 258 ? -3.403 21.572 21.365 1.00 4.92 ? 291 TYR A CB 1 ATOM 2059 C CG . TYR A 1 258 ? -2.120 22.262 21.849 1.00 5.03 ? 291 TYR A CG 1 ATOM 2060 C CD1 . TYR A 1 258 ? -1.046 22.425 21.001 1.00 5.20 ? 291 TYR A CD1 1 ATOM 2061 C CD2 . TYR A 1 258 ? -1.985 22.734 23.142 1.00 5.26 ? 291 TYR A CD2 1 ATOM 2062 C CE1 . TYR A 1 258 ? 0.134 23.026 21.416 1.00 5.33 ? 291 TYR A CE1 1 ATOM 2063 C CE2 . TYR A 1 258 ? -0.801 23.374 23.589 1.00 5.36 ? 291 TYR A CE2 1 ATOM 2064 C CZ . TYR A 1 258 ? 0.257 23.503 22.706 1.00 5.47 ? 291 TYR A CZ 1 ATOM 2065 O OH . TYR A 1 258 ? 1.466 24.077 23.066 1.00 5.81 ? 291 TYR A OH 1 ATOM 2066 N N . GLY A 1 259 ? -5.152 20.488 19.077 1.00 4.76 ? 292 GLY A N 1 ATOM 2067 C CA . GLY A 1 259 ? -6.174 19.535 18.664 1.00 4.75 ? 292 GLY A CA 1 ATOM 2068 C C . GLY A 1 259 ? -5.645 18.136 18.811 1.00 4.98 ? 292 GLY A C 1 ATOM 2069 O O . GLY A 1 259 ? -5.183 17.772 19.885 1.00 5.17 ? 292 GLY A O 1 ATOM 2070 N N . HIS A 1 260 ? -5.800 17.354 17.710 1.00 5.21 ? 293 HIS A N 1 ATOM 2071 C CA . HIS A 1 260 ? -5.159 16.057 17.441 1.00 5.11 ? 293 HIS A CA 1 ATOM 2072 C C . HIS A 1 260 ? -5.723 14.920 18.204 1.00 5.24 ? 293 HIS A C 1 ATOM 2073 O O . HIS A 1 260 ? -6.186 13.946 17.585 1.00 5.72 ? 293 HIS A O 1 ATOM 2074 C CB . HIS A 1 260 ? -3.690 16.164 17.526 1.00 5.22 ? 293 HIS A CB 1 ATOM 2075 C CG . HIS A 1 260 ? -2.981 14.857 17.395 1.00 5.46 ? 293 HIS A CG 1 ATOM 2076 N ND1 . HIS A 1 260 ? -2.800 14.228 16.182 1.00 5.59 ? 293 HIS A ND1 1 ATOM 2077 C CD2 . HIS A 1 260 ? -2.329 14.095 18.325 1.00 5.57 ? 293 HIS A CD2 1 ATOM 2078 C CE1 . HIS A 1 260 ? -2.153 13.083 16.378 1.00 5.77 ? 293 HIS A CE1 1 ATOM 2079 N NE2 . HIS A 1 260 ? -1.824 12.996 17.664 1.00 5.75 ? 293 HIS A NE2 1 ATOM 2080 N N . THR A 1 261 ? -5.790 15.024 19.528 1.00 5.26 ? 294 THR A N 1 ATOM 2081 C CA . THR A 1 261 ? -6.463 13.992 20.309 1.00 5.23 ? 294 THR A CA 1 ATOM 2082 C C . THR A 1 261 ? -7.925 13.765 20.062 1.00 5.27 ? 294 THR A C 1 ATOM 2083 O O . THR A 1 261 ? -8.398 12.708 20.333 1.00 5.67 ? 294 THR A O 1 ATOM 2084 C CB . THR A 1 261 ? -6.282 14.179 21.805 1.00 5.32 ? 294 THR A CB 1 ATOM 2085 O OG1 . THR A 1 261 ? -7.140 15.228 22.248 1.00 5.56 ? 294 THR A OG1 1 ATOM 2086 C CG2 . THR A 1 261 ? -4.802 14.469 22.159 1.00 5.26 ? 294 THR A CG2 1 ATOM 2087 N N . HIS A 1 262 ? -8.661 14.741 19.569 1.00 5.37 ? 295 HIS A N 1 ATOM 2088 C CA . HIS A 1 262 ? -10.096 14.620 19.335 1.00 5.34 ? 295 HIS A CA 1 ATOM 2089 C C . HIS A 1 262 ? -10.906 14.653 20.641 1.00 5.58 ? 295 HIS A C 1 ATOM 2090 O O . HIS A 1 262 ? -12.103 14.353 20.638 1.00 5.92 ? 295 HIS A O 1 ATOM 2091 C CB . HIS A 1 262 ? -10.437 13.376 18.518 1.00 5.27 ? 295 HIS A CB 1 ATOM 2092 C CG . HIS A 1 262 ? -9.892 13.380 17.134 1.00 5.24 ? 295 HIS A CG 1 ATOM 2093 N ND1 . HIS A 1 262 ? -10.345 12.512 16.174 1.00 5.37 ? 295 HIS A ND1 1 ATOM 2094 C CD2 . HIS A 1 262 ? -8.921 14.111 16.538 1.00 5.34 ? 295 HIS A CD2 1 ATOM 2095 C CE1 . HIS A 1 262 ? -9.669 12.695 15.048 1.00 5.24 ? 295 HIS A CE1 1 ATOM 2096 N NE2 . HIS A 1 262 ? -8.801 13.659 15.243 1.00 5.26 ? 295 HIS A NE2 1 ATOM 2097 N N . ARG A 1 263 ? -10.275 15.085 21.721 1.00 5.79 ? 296 ARG A N 1 ATOM 2098 C CA . ARG A 1 263 ? -10.893 15.149 23.043 1.00 6.02 ? 296 ARG A CA 1 ATOM 2099 C C . ARG A 1 263 ? -10.818 16.525 23.626 1.00 6.09 ? 296 ARG A C 1 ATOM 2100 O O . ARG A 1 263 ? -9.942 17.342 23.232 1.00 6.06 ? 296 ARG A O 1 ATOM 2101 C CB . ARG A 1 263 ? -10.155 14.196 24.000 1.00 6.25 ? 296 ARG A CB 1 ATOM 2102 C CG . ARG A 1 263 ? -10.195 12.740 23.528 1.00 6.29 ? 296 ARG A CG 1 ATOM 2103 C CD . ARG A 1 263 ? -11.618 12.272 23.539 1.00 6.43 ? 296 ARG A CD 1 ATOM 2104 N NE . ARG A 1 263 ? -11.623 10.886 23.141 1.00 6.87 ? 296 ARG A NE 1 ATOM 2105 C CZ . ARG A 1 263 ? -11.894 10.408 21.922 1.00 6.83 ? 296 ARG A CZ 1 ATOM 2106 N NH1 . ARG A 1 263 ? -12.263 11.185 20.873 1.00 6.68 1 296 ARG A NH1 1 ATOM 2107 N NH2 . ARG A 1 263 ? -11.780 9.096 21.773 1.00 6.81 ? 296 ARG A NH2 1 ATOM 2108 N N . ASP A 1 264 ? -11.703 16.746 24.598 1.00 6.02 ? 297 ASP A N 1 ATOM 2109 C CA . ASP A 1 264 ? -11.773 17.981 25.331 1.00 6.39 ? 297 ASP A CA 1 ATOM 2110 C C . ASP A 1 264 ? -10.945 17.920 26.644 1.00 6.88 ? 297 ASP A C 1 ATOM 2111 O O . ASP A 1 264 ? -11.357 17.319 27.609 1.00 7.27 ? 297 ASP A O 1 ATOM 2112 C CB . ASP A 1 264 ? -13.237 18.265 25.593 1.00 6.43 ? 297 ASP A CB 1 ATOM 2113 C CG . ASP A 1 264 ? -13.494 19.652 26.185 1.00 6.52 ? 297 ASP A CG 1 ATOM 2114 O OD1 . ASP A 1 264 ? -12.529 20.269 26.696 1.00 6.48 ? 297 ASP A OD1 1 ATOM 2115 O OD2 . ASP A 1 264 ? -14.689 20.107 26.156 1.00 6.43 -1 297 ASP A OD2 1 ATOM 2116 N N . SER A 1 265 ? -9.788 18.561 26.664 1.00 7.40 ? 298 SER A N 1 ATOM 2117 C CA . SER A 1 265 ? -8.919 18.592 27.814 1.00 8.23 ? 298 SER A CA 1 ATOM 2118 C C . SER A 1 265 ? -8.364 19.984 28.090 1.00 8.75 ? 298 SER A C 1 ATOM 2119 O O . SER A 1 265 ? -8.376 20.895 27.213 1.00 8.44 ? 298 SER A O 1 ATOM 2120 C CB . SER A 1 265 ? -7.696 17.759 27.542 1.00 8.84 ? 298 SER A CB 1 ATOM 2121 O OG . SER A 1 265 ? -8.014 16.403 27.503 1.00 10.20 ? 298 SER A OG 1 ATOM 2122 N N . ILE A 1 266 ? -7.822 20.099 29.298 1.00 8.80 ? 299 ILE A N 1 ATOM 2123 C CA . ILE A 1 266 ? -7.002 21.219 29.644 1.00 9.31 ? 299 ILE A CA 1 ATOM 2124 C C . ILE A 1 266 ? -5.709 20.774 30.214 1.00 9.36 ? 299 ILE A C 1 ATOM 2125 O O . ILE A 1 266 ? -5.612 19.689 30.718 1.00 9.20 ? 299 ILE A O 1 ATOM 2126 C CB . ILE A 1 266 ? -7.642 22.111 30.672 1.00 9.66 ? 299 ILE A CB 1 ATOM 2127 C CG1 . ILE A 1 266 ? -7.751 21.395 31.988 1.00 9.93 ? 299 ILE A CG1 1 ATOM 2128 C CG2 . ILE A 1 266 ? -9.015 22.495 30.177 1.00 10.52 ? 299 ILE A CG2 1 ATOM 2129 C CD1 . ILE A 1 266 ? -8.736 22.028 32.961 1.00 10.23 ? 299 ILE A CD1 1 ATOM 2130 N N . MET A 1 267 ? -4.710 21.630 30.137 1.00 9.69 ? 300 MET A N 1 ATOM 2131 C CA . MET A 1 267 ? -3.480 21.411 30.902 1.00 9.83 ? 300 MET A CA 1 ATOM 2132 C C . MET A 1 267 ? -3.131 22.706 31.529 1.00 9.36 ? 300 MET A C 1 ATOM 2133 O O . MET A 1 267 ? -3.503 23.754 31.029 1.00 8.33 ? 300 MET A O 1 ATOM 2134 C CB . MET A 1 267 ? -2.323 20.884 30.027 1.00 9.93 ? 300 MET A CB 1 ATOM 2135 C CG . MET A 1 267 ? -2.581 19.489 29.485 1.00 10.19 ? 300 MET A CG 1 ATOM 2136 S SD . MET A 1 267 ? -1.329 18.842 28.347 1.00 11.28 ? 300 MET A SD 1 ATOM 2137 C CE . MET A 1 267 ? -1.967 19.511 26.818 1.00 10.85 ? 300 MET A CE 1 ATOM 2138 N N . VAL A 1 268 ? -2.420 22.611 32.643 1.00 10.39 ? 301 VAL A N 1 ATOM 2139 C CA . VAL A 1 268 ? -1.878 23.798 33.308 1.00 11.12 ? 301 VAL A CA 1 ATOM 2140 C C . VAL A 1 268 ? -0.411 23.702 33.397 1.00 11.07 ? 301 VAL A C 1 ATOM 2141 O O . VAL A 1 268 ? 0.078 22.817 34.025 1.00 11.59 ? 301 VAL A O 1 ATOM 2142 C CB . VAL A 1 268 ? -2.422 23.951 34.709 1.00 11.75 ? 301 VAL A CB 1 ATOM 2143 C CG1 . VAL A 1 268 ? -1.843 25.194 35.340 1.00 12.15 ? 301 VAL A CG1 1 ATOM 2144 C CG2 . VAL A 1 268 ? -3.944 24.128 34.655 1.00 12.37 ? 301 VAL A CG2 1 ATOM 2145 N N . LEU A 1 269 ? 0.292 24.605 32.757 1.00 11.74 ? 302 LEU A N 1 ATOM 2146 C CA . LEU A 1 269 ? 1.747 24.604 32.809 1.00 13.33 ? 302 LEU A CA 1 ATOM 2147 C C . LEU A 1 269 ? 2.181 25.400 33.982 1.00 14.03 ? 302 LEU A C 1 ATOM 2148 O O . LEU A 1 269 ? 1.713 26.508 34.203 1.00 14.94 ? 302 LEU A O 1 ATOM 2149 C CB . LEU A 1 269 ? 2.310 25.237 31.541 1.00 15.02 ? 302 LEU A CB 1 ATOM 2150 C CG . LEU A 1 269 ? 3.816 25.479 31.446 1.00 15.86 ? 302 LEU A CG 1 ATOM 2151 C CD1 . LEU A 1 269 ? 4.577 24.166 31.467 1.00 16.00 ? 302 LEU A CD1 1 ATOM 2152 C CD2 . LEU A 1 269 ? 4.152 26.257 30.179 1.00 16.10 ? 302 LEU A CD2 1 ATOM 2153 N N . SER A 1 270 ? 3.077 24.838 34.756 1.00 16.11 ? 303 SER A N 1 ATOM 2154 C CA . SER A 1 270 ? 3.613 25.513 35.939 1.00 17.53 ? 303 SER A CA 1 ATOM 2155 C C . SER A 1 270 ? 5.031 25.889 35.696 1.00 18.99 ? 303 SER A C 1 ATOM 2156 O O . SER A 1 270 ? 5.717 25.300 34.854 1.00 17.76 ? 303 SER A O 1 ATOM 2157 C CB . SER A 1 270 ? 3.572 24.625 37.153 1.00 17.44 ? 303 SER A CB 1 ATOM 2158 O OG . SER A 1 270 ? 2.239 24.446 37.540 1.00 19.23 ? 303 SER A OG 1 ATOM 2159 N N . ASP A 1 271 ? 5.480 26.884 36.439 1.00 21.66 ? 304 ASP A N 1 ATOM 2160 C CA . ASP A 1 271 ? 6.840 27.353 36.271 1.00 24.86 ? 304 ASP A CA 1 ATOM 2161 C C . ASP A 1 271 ? 7.758 26.430 37.058 1.00 28.98 ? 304 ASP A C 1 ATOM 2162 O O . ASP A 1 271 ? 7.290 25.542 37.751 1.00 29.54 ? 304 ASP A O 1 ATOM 2163 C CB . ASP A 1 271 ? 6.954 28.811 36.684 1.00 24.40 ? 304 ASP A CB 1 ATOM 2164 C CG . ASP A 1 271 ? 6.867 29.025 38.182 1.00 24.44 ? 304 ASP A CG 1 ATOM 2165 O OD1 . ASP A 1 271 ? 6.693 28.082 38.992 1.00 24.00 ? 304 ASP A OD1 1 ATOM 2166 O OD2 . ASP A 1 271 ? 6.933 30.205 38.538 1.00 24.89 -1 304 ASP A OD2 1 ATOM 2167 N N . LYS A 1 272 ? 9.061 26.626 36.947 1.00 37.31 ? 305 LYS A N 1 ATOM 2168 C CA . LYS A 1 272 ? 10.040 25.708 37.567 1.00 42.68 ? 305 LYS A CA 1 ATOM 2169 C C . LYS A 1 272 ? 9.860 25.538 39.086 1.00 41.42 ? 305 LYS A C 1 ATOM 2170 O O . LYS A 1 272 ? 10.150 24.501 39.640 1.00 40.50 ? 305 LYS A O 1 ATOM 2171 C CB . LYS A 1 272 ? 11.433 26.202 37.246 1.00 47.55 ? 305 LYS A CB 1 ATOM 2172 C CG . LYS A 1 272 ? 11.733 26.209 35.748 1.00 52.79 ? 305 LYS A CG 1 ATOM 2173 C CD . LYS A 1 272 ? 12.618 25.025 35.385 1.00 60.26 ? 305 LYS A CD 1 ATOM 2174 C CE . LYS A 1 272 ? 12.661 24.737 33.894 1.00 67.64 ? 305 LYS A CE 1 ATOM 2175 N NZ . LYS A 1 272 ? 12.620 25.966 33.041 1.00 67.13 1 305 LYS A NZ 1 ATOM 2176 N N . LYS A 1 273 ? 9.313 26.552 39.729 1.00 43.99 ? 306 LYS A N 1 ATOM 2177 C CA . LYS A 1 273 ? 9.018 26.514 41.153 1.00 45.27 ? 306 LYS A CA 1 ATOM 2178 C C . LYS A 1 273 ? 7.615 25.972 41.511 1.00 43.86 ? 306 LYS A C 1 ATOM 2179 O O . LYS A 1 273 ? 7.216 26.095 42.680 1.00 44.08 ? 306 LYS A O 1 ATOM 2180 C CB . LYS A 1 273 ? 9.150 27.942 41.711 1.00 51.18 ? 306 LYS A CB 1 ATOM 2181 C CG . LYS A 1 273 ? 9.984 28.078 42.989 1.00 61.35 ? 306 LYS A CG 1 ATOM 2182 C CD . LYS A 1 273 ? 11.240 28.938 42.788 1.00 68.59 ? 306 LYS A CD 1 ATOM 2183 C CE . LYS A 1 273 ? 12.417 28.171 42.187 1.00 70.85 ? 306 LYS A CE 1 ATOM 2184 N NZ . LYS A 1 273 ? 13.128 27.386 43.237 1.00 73.16 1 306 LYS A NZ 1 ATOM 2185 N N . GLY A 1 274 ? 6.848 25.425 40.550 1.00 34.78 ? 307 GLY A N 1 ATOM 2186 C CA . GLY A 1 274 ? 5.527 24.823 40.864 1.00 30.31 ? 307 GLY A CA 1 ATOM 2187 C C . GLY A 1 274 ? 4.298 25.738 40.818 1.00 29.83 ? 307 GLY A C 1 ATOM 2188 O O . GLY A 1 274 ? 3.172 25.330 41.110 1.00 29.50 ? 307 GLY A O 1 ATOM 2189 N N . SER A 1 275 ? 4.508 26.977 40.411 1.00 26.69 ? 308 SER A N 1 ATOM 2190 C CA . SER A 1 275 ? 3.455 27.944 40.282 1.00 23.86 ? 308 SER A CA 1 ATOM 2191 C C . SER A 1 275 ? 2.810 27.907 38.885 1.00 21.09 ? 308 SER A C 1 ATOM 2192 O O . SER A 1 275 ? 3.495 27.941 37.878 1.00 19.72 ? 308 SER A O 1 ATOM 2193 C CB . SER A 1 275 ? 4.084 29.306 40.469 1.00 25.18 ? 308 SER A CB 1 ATOM 2194 O OG . SER A 1 275 ? 3.175 30.138 41.134 1.00 31.19 ? 308 SER A OG 1 ATOM 2195 N N . PRO A 1 276 ? 1.484 27.897 38.811 1.00 17.73 ? 309 PRO A N 1 ATOM 2196 C CA . PRO A 1 276 ? 0.855 27.793 37.528 1.00 16.08 ? 309 PRO A CA 1 ATOM 2197 C C . PRO A 1 276 ? 0.950 29.086 36.741 1.00 15.53 ? 309 PRO A C 1 ATOM 2198 O O . PRO A 1 276 ? 0.615 30.114 37.269 1.00 16.15 ? 309 PRO A O 1 ATOM 2199 C CB . PRO A 1 276 ? -0.575 27.492 37.883 1.00 15.50 ? 309 PRO A CB 1 ATOM 2200 C CG . PRO A 1 276 ? -0.762 28.098 39.188 1.00 16.24 ? 309 PRO A CG 1 ATOM 2201 C CD . PRO A 1 276 ? 0.536 28.244 39.864 1.00 16.64 ? 309 PRO A CD 1 ATOM 2202 N N . VAL A 1 277 ? 1.349 29.014 35.471 1.00 14.17 ? 310 VAL A N 1 ATOM 2203 C CA . VAL A 1 277 ? 1.575 30.199 34.666 1.00 13.49 ? 310 VAL A CA 1 ATOM 2204 C C . VAL A 1 277 ? 1.022 30.215 33.259 1.00 12.82 ? 310 VAL A C 1 ATOM 2205 O O . VAL A 1 277 ? 1.128 31.224 32.615 1.00 12.73 ? 310 VAL A O 1 ATOM 2206 C CB . VAL A 1 277 ? 3.093 30.465 34.474 1.00 14.06 ? 310 VAL A CB 1 ATOM 2207 C CG1 . VAL A 1 277 ? 3.734 30.778 35.825 1.00 14.16 ? 310 VAL A CG1 1 ATOM 2208 C CG2 . VAL A 1 277 ? 3.773 29.291 33.775 1.00 13.56 ? 310 VAL A CG2 1 ATOM 2209 N N . ASN A 1 278 ? 0.499 29.108 32.748 1.00 12.67 ? 311 ASN A N 1 ATOM 2210 C CA . ASN A 1 278 ? -0.094 29.093 31.415 1.00 11.78 ? 311 ASN A CA 1 ATOM 2211 C C . ASN A 1 278 ? -1.214 28.090 31.357 1.00 11.07 ? 311 ASN A C 1 ATOM 2212 O O . ASN A 1 278 ? -1.099 27.012 31.910 1.00 10.88 ? 311 ASN A O 1 ATOM 2213 C CB . ASN A 1 278 ? 0.932 28.698 30.392 1.00 12.13 ? 311 ASN A CB 1 ATOM 2214 C CG . ASN A 1 278 ? 1.073 29.710 29.284 1.00 13.12 ? 311 ASN A CG 1 ATOM 2215 O OD1 . ASN A 1 278 ? 0.979 29.361 28.109 1.00 15.03 ? 311 ASN A OD1 1 ATOM 2216 N ND2 . ASN A 1 278 ? 1.349 30.960 29.635 1.00 12.88 ? 311 ASN A ND2 1 ATOM 2217 N N . SER A 1 279 ? -2.287 28.473 30.667 1.00 10.13 ? 312 SER A N 1 ATOM 2218 C CA . SER A 1 279 ? -3.412 27.637 30.422 1.00 9.33 ? 312 SER A CA 1 ATOM 2219 C C . SER A 1 279 ? -3.362 27.067 29.014 1.00 8.60 ? 312 SER A C 1 ATOM 2220 O O . SER A 1 279 ? -3.107 27.804 28.047 1.00 9.49 ? 312 SER A O 1 ATOM 2221 C CB . SER A 1 279 ? -4.664 28.475 30.578 1.00 9.73 ? 312 SER A CB 1 ATOM 2222 O OG . SER A 1 279 ? -4.891 28.819 31.947 1.00 10.16 ? 312 SER A OG 1 ATOM 2223 N N . LEU A 1 280 ? -3.661 25.778 28.867 1.00 7.45 ? 313 LEU A N 1 ATOM 2224 C CA . LEU A 1 280 ? -3.657 25.138 27.556 1.00 6.52 ? 313 LEU A CA 1 ATOM 2225 C C . LEU A 1 280 ? -4.971 24.369 27.362 1.00 5.68 ? 313 LEU A C 1 ATOM 2226 O O . LEU A 1 280 ? -5.443 23.657 28.263 1.00 5.39 ? 313 LEU A O 1 ATOM 2227 C CB . LEU A 1 280 ? -2.510 24.155 27.474 1.00 6.85 ? 313 LEU A CB 1 ATOM 2228 C CG . LEU A 1 280 ? -1.033 24.569 27.575 1.00 7.30 ? 313 LEU A CG 1 ATOM 2229 C CD1 . LEU A 1 280 ? -0.692 25.140 28.938 1.00 7.59 ? 313 LEU A CD1 1 ATOM 2230 C CD2 . LEU A 1 280 ? -0.122 23.355 27.318 1.00 7.31 ? 313 LEU A CD2 1 ATOM 2231 N N . PHE A 1 281 ? -5.517 24.491 26.160 1.00 4.78 ? 314 PHE A N 1 ATOM 2232 C CA . PHE A 1 281 ? -6.807 23.974 25.804 1.00 4.17 ? 314 PHE A CA 1 ATOM 2233 C C . PHE A 1 281 ? -6.793 23.097 24.555 1.00 3.82 ? 314 PHE A C 1 ATOM 2234 O O . PHE A 1 281 ? -6.528 23.574 23.466 1.00 3.61 ? 314 PHE A O 1 ATOM 2235 C CB . PHE A 1 281 ? -7.738 25.123 25.544 1.00 4.10 ? 314 PHE A CB 1 ATOM 2236 C CG . PHE A 1 281 ? -7.822 26.074 26.676 1.00 4.15 ? 314 PHE A CG 1 ATOM 2237 C CD1 . PHE A 1 281 ? -8.686 25.859 27.706 1.00 4.25 ? 314 PHE A CD1 1 ATOM 2238 C CD2 . PHE A 1 281 ? -7.012 27.150 26.733 1.00 4.13 ? 314 PHE A CD2 1 ATOM 2239 C CE1 . PHE A 1 281 ? -8.731 26.716 28.781 1.00 4.22 ? 314 PHE A CE1 1 ATOM 2240 C CE2 . PHE A 1 281 ? -7.075 28.025 27.784 1.00 4.19 ? 314 PHE A CE2 1 ATOM 2241 C CZ . PHE A 1 281 ? -7.929 27.804 28.812 1.00 4.19 ? 314 PHE A CZ 1 ATOM 2242 N N . VAL A 1 282 ? -7.142 21.824 24.739 1.00 3.44 ? 315 VAL A N 1 ATOM 2243 C CA . VAL A 1 282 ? -7.227 20.903 23.664 1.00 3.19 ? 315 VAL A CA 1 ATOM 2244 C C . VAL A 1 282 ? -8.682 20.769 23.256 1.00 3.13 ? 315 VAL A C 1 ATOM 2245 O O . VAL A 1 282 ? -9.553 20.355 24.045 1.00 3.05 ? 315 VAL A O 1 ATOM 2246 C CB . VAL A 1 282 ? -6.670 19.554 24.089 1.00 3.14 ? 315 VAL A CB 1 ATOM 2247 C CG1 . VAL A 1 282 ? -6.695 18.592 22.938 1.00 3.14 ? 315 VAL A CG1 1 ATOM 2248 C CG2 . VAL A 1 282 ? -5.246 19.696 24.593 1.00 3.12 ? 315 VAL A CG2 1 ATOM 2249 N N . ALA A 1 283 ? -8.950 21.073 21.997 1.00 3.07 ? 316 ALA A N 1 ATOM 2250 C CA . ALA A 1 283 ? -10.325 21.107 21.528 1.00 3.04 ? 316 ALA A CA 1 ATOM 2251 C C . ALA A 1 283 ? -10.627 19.808 20.869 1.00 3.08 ? 316 ALA A C 1 ATOM 2252 O O . ALA A 1 283 ? -9.773 19.254 20.192 1.00 3.25 ? 316 ALA A O 1 ATOM 2253 C CB . ALA A 1 283 ? -10.482 22.209 20.556 1.00 3.00 ? 316 ALA A CB 1 ATOM 2254 N N . PRO A 1 284 ? -11.839 19.319 20.995 1.00 3.11 ? 317 PRO A N 1 ATOM 2255 C CA . PRO A 1 284 ? -12.185 18.047 20.326 1.00 3.16 ? 317 PRO A CA 1 ATOM 2256 C C . PRO A 1 284 ? -12.539 18.186 18.793 1.00 3.15 ? 317 PRO A C 1 ATOM 2257 O O . PRO A 1 284 ? -12.728 19.252 18.289 1.00 3.10 ? 317 PRO A O 1 ATOM 2258 C CB . PRO A 1 284 ? -13.387 17.560 21.153 1.00 3.14 ? 317 PRO A CB 1 ATOM 2259 C CG . PRO A 1 284 ? -14.085 18.851 21.513 1.00 3.16 ? 317 PRO A CG 1 ATOM 2260 C CD . PRO A 1 284 ? -12.972 19.863 21.751 1.00 3.16 ? 317 PRO A CD 1 ATOM 2261 N N . ALA A 1 285 ? -12.638 17.087 18.089 1.00 3.18 ? 318 ALA A N 1 ATOM 2262 C CA . ALA A 1 285 ? -12.766 17.105 16.658 1.00 3.24 ? 318 ALA A CA 1 ATOM 2263 C C . ALA A 1 285 ? -14.180 17.304 16.281 1.00 3.38 ? 318 ALA A C 1 ATOM 2264 O O . ALA A 1 285 ? -15.111 17.081 17.107 1.00 3.41 ? 318 ALA A O 1 ATOM 2265 C CB . ALA A 1 285 ? -12.328 15.774 16.083 1.00 3.31 ? 318 ALA A CB 1 ATOM 2266 N N . VAL A 1 286 ? -14.353 17.728 15.024 1.00 3.42 ? 319 VAL A N 1 ATOM 2267 C CA . VAL A 1 286 ? -15.622 17.631 14.325 1.00 3.47 ? 319 VAL A CA 1 ATOM 2268 C C . VAL A 1 286 ? -15.902 16.188 13.897 1.00 3.55 ? 319 VAL A C 1 ATOM 2269 O O . VAL A 1 286 ? -17.028 15.689 14.055 1.00 3.54 ? 319 VAL A O 1 ATOM 2270 C CB . VAL A 1 286 ? -15.610 18.553 13.115 1.00 3.57 ? 319 VAL A CB 1 ATOM 2271 C CG1 . VAL A 1 286 ? -16.830 18.369 12.267 1.00 3.66 ? 319 VAL A CG1 1 ATOM 2272 C CG2 . VAL A 1 286 ? -15.555 19.997 13.559 1.00 3.62 ? 319 VAL A CG2 1 ATOM 2273 N N . THR A 1 287 ? -14.895 15.478 13.374 1.00 3.68 ? 320 THR A N 1 ATOM 2274 C CA . THR A 1 287 ? -15.147 14.087 13.011 1.00 3.76 ? 320 THR A CA 1 ATOM 2275 C C . THR A 1 287 ? -15.441 13.299 14.285 1.00 3.93 ? 320 THR A C 1 ATOM 2276 O O . THR A 1 287 ? -14.857 13.575 15.323 1.00 3.98 ? 320 THR A O 1 ATOM 2277 C CB . THR A 1 287 ? -13.960 13.433 12.346 1.00 3.83 ? 320 THR A CB 1 ATOM 2278 O OG1 . THR A 1 287 ? -14.305 12.090 11.984 1.00 3.98 ? 320 THR A OG1 1 ATOM 2279 C CG2 . THR A 1 287 ? -12.733 13.330 13.298 1.00 3.87 ? 320 THR A CG2 1 ATOM 2280 N N . PRO A 1 288 ? -16.312 12.288 14.211 1.00 4.10 ? 321 PRO A N 1 ATOM 2281 C CA . PRO A 1 288 ? -16.618 11.394 15.283 1.00 4.13 ? 321 PRO A CA 1 ATOM 2282 C C . PRO A 1 288 ? -15.910 10.070 15.227 1.00 4.39 ? 321 PRO A C 1 ATOM 2283 O O . PRO A 1 288 ? -16.155 9.179 16.068 1.00 4.35 ? 321 PRO A O 1 ATOM 2284 C CB . PRO A 1 288 ? -18.094 11.152 15.049 1.00 4.11 ? 321 PRO A CB 1 ATOM 2285 C CG . PRO A 1 288 ? -18.202 11.116 13.582 1.00 4.04 ? 321 PRO A CG 1 ATOM 2286 C CD . PRO A 1 288 ? -17.282 12.154 13.099 1.00 4.07 ? 321 PRO A CD 1 ATOM 2287 N N . VAL A 1 289 ? -15.031 9.906 14.268 1.00 4.82 ? 322 VAL A N 1 ATOM 2288 C CA . VAL A 1 289 ? -14.576 8.582 13.953 1.00 5.32 ? 322 VAL A CA 1 ATOM 2289 C C . VAL A 1 289 ? -13.944 7.818 15.123 1.00 6.15 ? 322 VAL A C 1 ATOM 2290 O O . VAL A 1 289 ? -13.220 8.408 15.903 1.00 6.87 ? 322 VAL A O 1 ATOM 2291 C CB . VAL A 1 289 ? -13.553 8.617 12.800 1.00 5.24 ? 322 VAL A CB 1 ATOM 2292 C CG1 . VAL A 1 289 ? -12.250 9.223 13.231 1.00 5.05 ? 322 VAL A CG1 1 ATOM 2293 C CG2 . VAL A 1 289 ? -13.316 7.191 12.271 1.00 5.23 ? 322 VAL A CG2 1 ATOM 2294 N N . LYS A 1 290 ? -14.169 6.513 15.231 1.00 6.81 ? 323 LYS A N 1 ATOM 2295 C CA . LYS A 1 290 ? -13.305 5.704 16.057 1.00 7.39 ? 323 LYS A CA 1 ATOM 2296 C C . LYS A 1 290 ? -13.067 4.325 15.458 1.00 7.86 ? 323 LYS A C 1 ATOM 2297 O O . LYS A 1 290 ? -13.691 3.939 14.447 1.00 8.25 ? 323 LYS A O 1 ATOM 2298 C CB . LYS A 1 290 ? -13.963 5.518 17.401 1.00 7.87 ? 323 LYS A CB 1 ATOM 2299 C CG . LYS A 1 290 ? -15.326 4.876 17.285 1.00 8.53 ? 323 LYS A CG 1 ATOM 2300 C CD . LYS A 1 290 ? -15.895 4.570 18.632 1.00 9.11 ? 323 LYS A CD 1 ATOM 2301 C CE . LYS A 1 290 ? -17.183 3.788 18.537 1.00 9.76 ? 323 LYS A CE 1 ATOM 2302 N NZ . LYS A 1 290 ? -16.813 2.366 18.623 1.00 10.63 1 323 LYS A NZ 1 ATOM 2303 N N . SER A 1 291 ? -12.196 3.581 16.111 1.00 7.82 ? 324 SER A N 1 ATOM 2304 C CA A SER A 1 291 ? -12.014 2.191 15.794 0.50 8.31 ? 324 SER A CA 1 ATOM 2305 C CA B SER A 1 291 ? -11.997 2.176 15.832 0.50 8.28 ? 324 SER A CA 1 ATOM 2306 C C . SER A 1 291 ? -13.147 1.355 16.353 1.00 8.85 ? 324 SER A C 1 ATOM 2307 O O . SER A 1 291 ? -13.820 1.730 17.329 1.00 9.72 ? 324 SER A O 1 ATOM 2308 C CB A SER A 1 291 ? -10.712 1.669 16.389 0.50 8.34 ? 324 SER A CB 1 ATOM 2309 C CB B SER A 1 291 ? -10.746 1.640 16.535 0.50 8.29 ? 324 SER A CB 1 ATOM 2310 O OG A SER A 1 291 ? -9.601 2.261 15.748 0.50 8.20 ? 324 SER A OG 1 ATOM 2311 O OG B SER A 1 291 ? -10.929 0.292 16.958 0.50 8.05 ? 324 SER A OG 1 ATOM 2312 N N . VAL A 1 292 ? -13.336 0.199 15.744 1.00 9.64 ? 325 VAL A N 1 ATOM 2313 C CA . VAL A 1 292 ? -14.374 -0.708 16.154 1.00 9.96 ? 325 VAL A CA 1 ATOM 2314 C C . VAL A 1 292 ? -14.171 -1.159 17.570 1.00 10.38 ? 325 VAL A C 1 ATOM 2315 O O . VAL A 1 292 ? -15.166 -1.386 18.261 1.00 11.78 ? 325 VAL A O 1 ATOM 2316 C CB . VAL A 1 292 ? -14.411 -1.996 15.348 1.00 9.93 ? 325 VAL A CB 1 ATOM 2317 C CG1 . VAL A 1 292 ? -15.641 -2.760 15.800 1.00 10.34 ? 325 VAL A CG1 1 ATOM 2318 C CG2 . VAL A 1 292 ? -14.476 -1.719 13.866 1.00 9.85 ? 325 VAL A CG2 1 ATOM 2319 N N . LEU A 1 293 ? -12.927 -1.319 18.012 1.00 10.17 ? 326 LEU A N 1 ATOM 2320 C CA . LEU A 1 293 ? -12.700 -1.849 19.366 1.00 10.32 ? 326 LEU A CA 1 ATOM 2321 C C . LEU A 1 293 ? -12.805 -0.856 20.491 1.00 9.90 ? 326 LEU A C 1 ATOM 2322 O O . LEU A 1 293 ? -12.806 -1.240 21.650 1.00 9.74 ? 326 LEU A O 1 ATOM 2323 C CB . LEU A 1 293 ? -11.371 -2.592 19.434 1.00 10.80 ? 326 LEU A CB 1 ATOM 2324 C CG . LEU A 1 293 ? -11.458 -3.824 18.533 1.00 11.96 ? 326 LEU A CG 1 ATOM 2325 C CD1 . LEU A 1 293 ? -10.180 -4.614 18.626 1.00 13.22 ? 326 LEU A CD1 1 ATOM 2326 C CD2 . LEU A 1 293 ? -12.634 -4.765 18.825 1.00 11.99 ? 326 LEU A CD2 1 ATOM 2327 N N . GLU A 1 294 ? -12.891 0.432 20.153 1.00 10.09 ? 327 GLU A N 1 ATOM 2328 C CA . GLU A 1 294 ? -13.097 1.499 21.146 1.00 9.37 ? 327 GLU A CA 1 ATOM 2329 C C . GLU A 1 294 ? -14.538 1.579 21.606 1.00 8.32 ? 327 GLU A C 1 ATOM 2330 O O . GLU A 1 294 ? -15.421 1.667 20.829 1.00 7.75 ? 327 GLU A O 1 ATOM 2331 C CB . GLU A 1 294 ? -12.651 2.837 20.590 1.00 9.88 ? 327 GLU A CB 1 ATOM 2332 C CG . GLU A 1 294 ? -11.162 2.846 20.512 1.00 11.22 ? 327 GLU A CG 1 ATOM 2333 C CD . GLU A 1 294 ? -10.542 3.923 19.644 1.00 13.18 ? 327 GLU A CD 1 ATOM 2334 O OE1 . GLU A 1 294 ? -9.410 4.301 20.007 1.00 18.05 ? 327 GLU A OE1 1 ATOM 2335 O OE2 . GLU A 1 294 ? -11.056 4.366 18.598 1.00 13.55 -1 327 GLU A OE2 1 ATOM 2336 N N . LYS A 1 295 ? -14.752 1.595 22.901 1.00 7.89 ? 328 LYS A N 1 ATOM 2337 C CA . LYS A 1 295 ? -16.055 1.858 23.417 1.00 8.05 ? 328 LYS A CA 1 ATOM 2338 C C . LYS A 1 295 ? -16.528 3.263 23.200 1.00 7.73 ? 328 LYS A C 1 ATOM 2339 O O . LYS A 1 295 ? -17.708 3.482 22.977 1.00 8.01 ? 328 LYS A O 1 ATOM 2340 C CB . LYS A 1 295 ? -16.068 1.579 24.898 1.00 9.04 ? 328 LYS A CB 1 ATOM 2341 C CG . LYS A 1 295 ? -17.250 2.177 25.648 1.00 10.15 ? 328 LYS A CG 1 ATOM 2342 C CD . LYS A 1 295 ? -18.547 1.490 25.254 1.00 11.17 ? 328 LYS A CD 1 ATOM 2343 C CE . LYS A 1 295 ? -19.754 2.231 25.884 1.00 12.17 ? 328 LYS A CE 1 ATOM 2344 N NZ . LYS A 1 295 ? -20.162 3.483 25.095 1.00 12.86 1 328 LYS A NZ 1 ATOM 2345 N N . GLN A 1 296 ? -15.647 4.239 23.355 1.00 7.29 ? 329 GLN A N 1 ATOM 2346 C CA . GLN A 1 296 ? -16.041 5.632 23.303 1.00 7.00 ? 329 GLN A CA 1 ATOM 2347 C C . GLN A 1 296 ? -15.479 6.359 22.087 1.00 6.45 ? 329 GLN A C 1 ATOM 2348 O O . GLN A 1 296 ? -14.468 5.997 21.560 1.00 6.11 ? 329 GLN A O 1 ATOM 2349 C CB . GLN A 1 296 ? -15.505 6.312 24.559 1.00 7.49 ? 329 GLN A CB 1 ATOM 2350 C CG . GLN A 1 296 ? -16.188 5.868 25.829 1.00 7.89 ? 329 GLN A CG 1 ATOM 2351 C CD . GLN A 1 296 ? -17.591 6.404 25.873 1.00 8.63 ? 329 GLN A CD 1 ATOM 2352 O OE1 . GLN A 1 296 ? -18.553 5.722 25.552 1.00 9.38 ? 329 GLN A OE1 1 ATOM 2353 N NE2 . GLN A 1 296 ? -17.714 7.676 26.218 1.00 9.29 ? 329 GLN A NE2 1 ATOM 2354 N N . THR A 1 297 ? -16.156 7.406 21.646 1.00 5.98 ? 330 THR A N 1 ATOM 2355 C CA . THR A 1 297 ? -15.571 8.371 20.734 1.00 5.62 ? 330 THR A CA 1 ATOM 2356 C C . THR A 1 297 ? -16.038 9.731 21.193 1.00 5.50 ? 330 THR A C 1 ATOM 2357 O O . THR A 1 297 ? -16.682 9.819 22.222 1.00 5.68 ? 330 THR A O 1 ATOM 2358 C CB . THR A 1 297 ? -16.007 8.082 19.310 1.00 5.54 ? 330 THR A CB 1 ATOM 2359 O OG1 . THR A 1 297 ? -15.223 8.867 18.442 1.00 5.38 ? 330 THR A OG1 1 ATOM 2360 C CG2 . THR A 1 297 ? -17.530 8.388 19.071 1.00 5.62 ? 330 THR A CG2 1 ATOM 2361 N N . ASN A 1 298 ? -15.758 10.785 20.447 1.00 5.28 ? 331 ASN A N 1 ATOM 2362 C CA . ASN A 1 298 ? -16.380 12.113 20.741 1.00 5.08 ? 331 ASN A CA 1 ATOM 2363 C C . ASN A 1 298 ? -17.545 12.366 19.832 1.00 5.09 ? 331 ASN A C 1 ATOM 2364 O O . ASN A 1 298 ? -17.532 11.900 18.674 1.00 5.30 ? 331 ASN A O 1 ATOM 2365 C CB . ASN A 1 298 ? -15.404 13.256 20.476 1.00 5.02 ? 331 ASN A CB 1 ATOM 2366 C CG . ASN A 1 298 ? -14.808 13.197 19.081 1.00 4.91 ? 331 ASN A CG 1 ATOM 2367 O OD1 . ASN A 1 298 ? -14.064 12.333 18.809 1.00 5.02 ? 331 ASN A OD1 1 ATOM 2368 N ND2 . ASN A 1 298 ? -15.158 14.088 18.223 1.00 4.94 ? 331 ASN A ND2 1 ATOM 2369 N N . ASN A 1 299 ? -18.539 13.117 20.306 1.00 4.91 ? 332 ASN A N 1 ATOM 2370 C CA . ASN A 1 299 ? -19.462 13.745 19.401 1.00 4.86 ? 332 ASN A CA 1 ATOM 2371 C C . ASN A 1 299 ? -18.716 14.900 18.753 1.00 4.66 ? 332 ASN A C 1 ATOM 2372 O O . ASN A 1 299 ? -17.715 15.416 19.292 1.00 4.67 ? 332 ASN A O 1 ATOM 2373 C CB . ASN A 1 299 ? -20.643 14.348 20.103 1.00 5.12 ? 332 ASN A CB 1 ATOM 2374 C CG . ASN A 1 299 ? -21.730 13.354 20.475 1.00 5.45 ? 332 ASN A CG 1 ATOM 2375 O OD1 . ASN A 1 299 ? -22.208 13.357 21.644 1.00 6.16 ? 332 ASN A OD1 1 ATOM 2376 N ND2 . ASN A 1 299 ? -22.188 12.573 19.531 1.00 5.46 ? 332 ASN A ND2 1 ATOM 2377 N N . PRO A 1 300 ? -19.199 15.330 17.595 1.00 4.54 ? 333 PRO A N 1 ATOM 2378 C CA . PRO A 1 300 ? -18.583 16.476 16.934 1.00 4.61 ? 333 PRO A CA 1 ATOM 2379 C C . PRO A 1 300 ? -18.677 17.764 17.756 1.00 4.90 ? 333 PRO A C 1 ATOM 2380 O O . PRO A 1 300 ? -19.704 18.021 18.372 1.00 4.58 ? 333 PRO A O 1 ATOM 2381 C CB . PRO A 1 300 ? -19.392 16.611 15.661 1.00 4.46 ? 333 PRO A CB 1 ATOM 2382 C CG . PRO A 1 300 ? -19.961 15.277 15.433 1.00 4.34 ? 333 PRO A CG 1 ATOM 2383 C CD . PRO A 1 300 ? -20.146 14.621 16.726 1.00 4.30 ? 333 PRO A CD 1 ATOM 2384 N N . GLY A 1 301 ? -17.585 18.550 17.733 1.00 5.36 ? 334 GLY A N 1 ATOM 2385 C CA . GLY A 1 301 ? -17.480 19.741 18.562 1.00 5.73 ? 334 GLY A CA 1 ATOM 2386 C C . GLY A 1 301 ? -16.928 20.984 17.867 1.00 6.17 ? 334 GLY A C 1 ATOM 2387 O O . GLY A 1 301 ? -16.104 20.896 16.980 1.00 5.96 ? 334 GLY A O 1 ATOM 2388 N N . ILE A 1 302 ? -17.350 22.135 18.351 1.00 6.61 ? 335 ILE A N 1 ATOM 2389 C CA . ILE A 1 302 ? -16.923 23.419 17.839 1.00 7.37 ? 335 ILE A CA 1 ATOM 2390 C C . ILE A 1 302 ? -16.873 24.283 19.095 1.00 7.13 ? 335 ILE A C 1 ATOM 2391 O O . ILE A 1 302 ? -17.789 24.168 19.933 1.00 7.25 ? 335 ILE A O 1 ATOM 2392 C CB . ILE A 1 302 ? -18.065 23.983 16.978 1.00 8.55 ? 335 ILE A CB 1 ATOM 2393 C CG1 . ILE A 1 302 ? -18.149 23.260 15.671 1.00 9.50 ? 335 ILE A CG1 1 ATOM 2394 C CG2 . ILE A 1 302 ? -17.893 25.439 16.672 1.00 9.24 ? 335 ILE A CG2 1 ATOM 2395 C CD1 . ILE A 1 302 ? -16.827 23.346 14.939 1.00 9.70 ? 335 ILE A CD1 1 ATOM 2396 N N . ARG A 1 303 ? -15.893 25.161 19.243 1.00 6.47 ? 336 ARG A N 1 ATOM 2397 C CA . ARG A 1 303 ? -15.877 25.973 20.431 1.00 6.39 ? 336 ARG A CA 1 ATOM 2398 C C . ARG A 1 303 ? -15.568 27.441 20.209 1.00 6.87 ? 336 ARG A C 1 ATOM 2399 O O . ARG A 1 303 ? -14.957 27.823 19.190 1.00 7.28 ? 336 ARG A O 1 ATOM 2400 C CB . ARG A 1 303 ? -14.913 25.412 21.454 1.00 5.97 ? 336 ARG A CB 1 ATOM 2401 C CG . ARG A 1 303 ? -13.456 25.465 21.024 1.00 5.71 ? 336 ARG A CG 1 ATOM 2402 C CD . ARG A 1 303 ? -12.506 25.040 22.123 1.00 5.45 ? 336 ARG A CD 1 ATOM 2403 N NE . ARG A 1 303 ? -12.945 23.887 22.891 1.00 5.29 ? 336 ARG A NE 1 ATOM 2404 C CZ . ARG A 1 303 ? -12.206 23.292 23.818 1.00 5.35 ? 336 ARG A CZ 1 ATOM 2405 N NH1 . ARG A 1 303 ? -10.957 23.652 24.060 1.00 5.48 1 336 ARG A NH1 1 ATOM 2406 N NH2 . ARG A 1 303 ? -12.685 22.306 24.514 1.00 5.39 ? 336 ARG A NH2 1 ATOM 2407 N N . LEU A 1 304 ? -15.932 28.241 21.225 1.00 6.97 ? 337 LEU A N 1 ATOM 2408 C CA . LEU A 1 304 ? -15.847 29.675 21.167 1.00 7.06 ? 337 LEU A CA 1 ATOM 2409 C C . LEU A 1 304 ? -15.203 30.238 22.423 1.00 6.95 ? 337 LEU A C 1 ATOM 2410 O O . LEU A 1 304 ? -15.710 29.997 23.530 1.00 7.33 ? 337 LEU A O 1 ATOM 2411 C CB . LEU A 1 304 ? -17.251 30.215 21.010 1.00 7.31 ? 337 LEU A CB 1 ATOM 2412 C CG . LEU A 1 304 ? -17.466 31.735 20.960 1.00 7.50 ? 337 LEU A CG 1 ATOM 2413 C CD1 . LEU A 1 304 ? -17.137 32.265 19.606 1.00 7.62 ? 337 LEU A CD1 1 ATOM 2414 C CD2 . LEU A 1 304 ? -18.905 32.141 21.244 1.00 7.78 ? 337 LEU A CD2 1 ATOM 2415 N N . PHE A 1 305 ? -14.115 30.999 22.259 1.00 6.64 ? 338 PHE A N 1 ATOM 2416 C CA . PHE A 1 305 ? -13.392 31.572 23.388 1.00 6.48 ? 338 PHE A CA 1 ATOM 2417 C C . PHE A 1 305 ? -13.773 33.041 23.514 1.00 7.13 ? 338 PHE A C 1 ATOM 2418 O O . PHE A 1 305 ? -14.045 33.729 22.519 1.00 6.71 ? 338 PHE A O 1 ATOM 2419 C CB . PHE A 1 305 ? -11.878 31.459 23.225 1.00 6.16 ? 338 PHE A CB 1 ATOM 2420 C CG . PHE A 1 305 ? -11.327 30.100 23.532 1.00 5.92 ? 338 PHE A CG 1 ATOM 2421 C CD1 . PHE A 1 305 ? -10.990 29.750 24.803 1.00 5.77 ? 338 PHE A CD1 1 ATOM 2422 C CD2 . PHE A 1 305 ? -11.132 29.175 22.538 1.00 5.94 ? 338 PHE A CD2 1 ATOM 2423 C CE1 . PHE A 1 305 ? -10.472 28.524 25.092 1.00 5.71 ? 338 PHE A CE1 1 ATOM 2424 C CE2 . PHE A 1 305 ? -10.611 27.924 22.829 1.00 6.00 ? 338 PHE A CE2 1 ATOM 2425 C CZ . PHE A 1 305 ? -10.273 27.611 24.112 1.00 5.83 ? 338 PHE A CZ 1 ATOM 2426 N N . GLN A 1 306 ? -13.813 33.501 24.764 1.00 8.00 ? 339 GLN A N 1 ATOM 2427 C CA . GLN A 1 306 ? -14.030 34.916 25.080 1.00 8.74 ? 339 GLN A CA 1 ATOM 2428 C C . GLN A 1 306 ? -12.779 35.468 25.709 1.00 8.86 ? 339 GLN A C 1 ATOM 2429 O O . GLN A 1 306 ? -12.178 34.817 26.578 1.00 9.15 ? 339 GLN A O 1 ATOM 2430 C CB . GLN A 1 306 ? -15.164 35.061 26.056 1.00 9.29 ? 339 GLN A CB 1 ATOM 2431 C CG . GLN A 1 306 ? -16.471 34.728 25.394 1.00 9.86 ? 339 GLN A CG 1 ATOM 2432 C CD . GLN A 1 306 ? -17.644 34.825 26.318 1.00 10.52 ? 339 GLN A CD 1 ATOM 2433 O OE1 . GLN A 1 306 ? -17.560 34.627 27.536 1.00 12.10 ? 339 GLN A OE1 1 ATOM 2434 N NE2 . GLN A 1 306 ? -18.749 35.124 25.754 1.00 10.67 ? 339 GLN A NE2 1 ATOM 2435 N N . TYR A 1 307 ? -12.373 36.639 25.255 1.00 9.03 ? 340 TYR A N 1 ATOM 2436 C CA . TYR A 1 307 ? -11.176 37.267 25.774 1.00 9.50 ? 340 TYR A CA 1 ATOM 2437 C C . TYR A 1 307 ? -11.409 38.756 26.053 1.00 9.53 ? 340 TYR A C 1 ATOM 2438 O O . TYR A 1 307 ? -12.327 39.369 25.520 1.00 9.23 ? 340 TYR A O 1 ATOM 2439 C CB . TYR A 1 307 ? -10.004 37.060 24.828 1.00 9.77 ? 340 TYR A CB 1 ATOM 2440 C CG . TYR A 1 307 ? -10.155 37.733 23.490 1.00 10.65 ? 340 TYR A CG 1 ATOM 2441 C CD1 . TYR A 1 307 ? -10.867 37.143 22.463 1.00 11.47 ? 340 TYR A CD1 1 ATOM 2442 C CD2 . TYR A 1 307 ? -9.592 38.969 23.240 1.00 11.02 ? 340 TYR A CD2 1 ATOM 2443 C CE1 . TYR A 1 307 ? -10.983 37.764 21.223 1.00 11.52 ? 340 TYR A CE1 1 ATOM 2444 C CE2 . TYR A 1 307 ? -9.724 39.572 22.019 1.00 11.09 ? 340 TYR A CE2 1 ATOM 2445 C CZ . TYR A 1 307 ? -10.424 38.961 21.031 1.00 11.13 ? 340 TYR A CZ 1 ATOM 2446 O OH . TYR A 1 307 ? -10.569 39.573 19.843 1.00 12.21 ? 340 TYR A OH 1 ATOM 2447 N N . ASP A 1 308 ? -10.573 39.285 26.934 1.00 9.93 ? 341 ASP A N 1 ATOM 2448 C CA . ASP A 1 308 ? -10.546 40.675 27.309 1.00 10.28 ? 341 ASP A CA 1 ATOM 2449 C C . ASP A 1 308 ? -9.693 41.366 26.275 1.00 10.69 ? 341 ASP A C 1 ATOM 2450 O O . ASP A 1 308 ? -8.507 41.034 26.163 1.00 11.55 ? 341 ASP A O 1 ATOM 2451 C CB . ASP A 1 308 ? -9.843 40.799 28.651 1.00 10.42 ? 341 ASP A CB 1 ATOM 2452 C CG . ASP A 1 308 ? -9.959 42.181 29.262 1.00 10.92 ? 341 ASP A CG 1 ATOM 2453 O OD1 . ASP A 1 308 ? -9.925 43.203 28.574 1.00 10.55 ? 341 ASP A OD1 1 ATOM 2454 O OD2 . ASP A 1 308 ? -10.082 42.244 30.498 1.00 12.30 -1 341 ASP A OD2 1 ATOM 2455 N N . PRO A 1 309 ? -10.240 42.335 25.553 1.00 10.34 ? 342 PRO A N 1 ATOM 2456 C CA . PRO A 1 309 ? -9.473 42.969 24.472 1.00 10.90 ? 342 PRO A CA 1 ATOM 2457 C C . PRO A 1 309 ? -8.347 43.874 24.859 1.00 11.35 ? 342 PRO A C 1 ATOM 2458 O O . PRO A 1 309 ? -7.631 44.307 23.987 1.00 12.26 ? 342 PRO A O 1 ATOM 2459 C CB . PRO A 1 309 ? -10.475 43.813 23.739 1.00 10.98 ? 342 PRO A CB 1 ATOM 2460 C CG . PRO A 1 309 ? -11.817 43.256 24.159 1.00 11.37 ? 342 PRO A CG 1 ATOM 2461 C CD . PRO A 1 309 ? -11.657 42.666 25.521 1.00 10.61 ? 342 PRO A CD 1 ATOM 2462 N N . ARG A 1 310 ? -8.165 44.152 26.140 1.00 12.13 ? 343 ARG A N 1 ATOM 2463 C CA . ARG A 1 310 ? -7.067 45.024 26.609 1.00 12.10 ? 343 ARG A CA 1 ATOM 2464 C C . ARG A 1 310 ? -5.793 44.239 26.827 1.00 11.88 ? 343 ARG A C 1 ATOM 2465 O O . ARG A 1 310 ? -4.788 44.576 26.298 1.00 12.70 ? 343 ARG A O 1 ATOM 2466 C CB . ARG A 1 310 ? -7.451 45.724 27.902 1.00 12.86 ? 343 ARG A CB 1 ATOM 2467 C CG . ARG A 1 310 ? -8.719 46.527 27.747 1.00 14.12 ? 343 ARG A CG 1 ATOM 2468 C CD . ARG A 1 310 ? -9.293 46.949 29.059 1.00 15.49 ? 343 ARG A CD 1 ATOM 2469 N NE . ARG A 1 310 ? -9.695 45.789 29.830 1.00 17.18 ? 343 ARG A NE 1 ATOM 2470 C CZ . ARG A 1 310 ? -10.368 45.836 30.975 1.00 16.93 ? 343 ARG A CZ 1 ATOM 2471 N NH1 . ARG A 1 310 ? -10.715 46.989 31.510 1.00 17.40 1 343 ARG A NH1 1 ATOM 2472 N NH2 . ARG A 1 310 ? -10.683 44.723 31.573 1.00 16.28 ? 343 ARG A NH2 1 ATOM 2473 N N . ASP A 1 311 ? -5.831 43.170 27.609 1.00 11.80 ? 344 ASP A N 1 ATOM 2474 C CA . ASP A 1 311 ? -4.630 42.359 27.849 1.00 11.13 ? 344 ASP A CA 1 ATOM 2475 C C . ASP A 1 311 ? -4.706 40.941 27.205 1.00 11.00 ? 344 ASP A C 1 ATOM 2476 O O . ASP A 1 311 ? -3.755 40.176 27.291 1.00 11.84 ? 344 ASP A O 1 ATOM 2477 C CB . ASP A 1 311 ? -4.325 42.299 29.335 1.00 10.37 ? 344 ASP A CB 1 ATOM 2478 C CG . ASP A 1 311 ? -5.374 41.654 30.077 1.00 10.77 ? 344 ASP A CG 1 ATOM 2479 O OD1 . ASP A 1 311 ? -6.274 41.141 29.447 1.00 10.29 ? 344 ASP A OD1 1 ATOM 2480 O OD2 . ASP A 1 311 ? -5.338 41.612 31.326 1.00 13.23 -1 344 ASP A OD2 1 ATOM 2481 N N . TYR A 1 312 ? -5.800 40.614 26.535 1.00 10.40 ? 345 TYR A N 1 ATOM 2482 C CA . TYR A 1 312 ? -5.959 39.283 25.906 1.00 10.70 ? 345 TYR A CA 1 ATOM 2483 C C . TYR A 1 312 ? -6.065 38.078 26.849 1.00 10.95 ? 345 TYR A C 1 ATOM 2484 O O . TYR A 1 312 ? -5.942 36.932 26.421 1.00 10.57 ? 345 TYR A O 1 ATOM 2485 C CB . TYR A 1 312 ? -4.914 39.099 24.791 1.00 10.72 ? 345 TYR A CB 1 ATOM 2486 C CG . TYR A 1 312 ? -5.065 40.288 23.830 1.00 10.78 ? 345 TYR A CG 1 ATOM 2487 C CD1 . TYR A 1 312 ? -6.247 40.446 23.084 1.00 10.67 ? 345 TYR A CD1 1 ATOM 2488 C CD2 . TYR A 1 312 ? -4.139 41.313 23.792 1.00 10.33 ? 345 TYR A CD2 1 ATOM 2489 C CE1 . TYR A 1 312 ? -6.441 41.556 22.307 1.00 10.67 ? 345 TYR A CE1 1 ATOM 2490 C CE2 . TYR A 1 312 ? -4.335 42.407 22.974 1.00 10.26 ? 345 TYR A CE2 1 ATOM 2491 C CZ . TYR A 1 312 ? -5.474 42.515 22.250 1.00 10.21 ? 345 TYR A CZ 1 ATOM 2492 O OH . TYR A 1 312 ? -5.687 43.594 21.462 1.00 10.78 ? 345 TYR A OH 1 ATOM 2493 N N . LYS A 1 313 ? -6.368 38.373 28.104 1.00 11.25 ? 346 LYS A N 1 ATOM 2494 C CA . LYS A 1 313 ? -6.741 37.409 29.115 1.00 12.73 ? 346 LYS A CA 1 ATOM 2495 C C . LYS A 1 313 ? -7.966 36.625 28.654 1.00 11.56 ? 346 LYS A C 1 ATOM 2496 O O . LYS A 1 313 ? -8.915 37.208 28.099 1.00 11.15 ? 346 LYS A O 1 ATOM 2497 C CB . LYS A 1 313 ? -7.016 38.181 30.426 1.00 15.84 ? 346 LYS A CB 1 ATOM 2498 C CG . LYS A 1 313 ? -7.732 37.428 31.562 1.00 19.94 ? 346 LYS A CG 1 ATOM 2499 C CD . LYS A 1 313 ? -7.684 38.120 32.946 1.00 22.15 ? 346 LYS A CD 1 ATOM 2500 C CE . LYS A 1 313 ? -8.546 39.389 33.066 1.00 25.14 ? 346 LYS A CE 1 ATOM 2501 N NZ . LYS A 1 313 ? -7.933 40.672 32.546 1.00 27.02 1 346 LYS A NZ 1 ATOM 2502 N N . LEU A 1 314 ? -7.944 35.309 28.849 1.00 10.37 ? 347 LEU A N 1 ATOM 2503 C CA . LEU A 1 314 ? -9.125 34.461 28.517 1.00 9.95 ? 347 LEU A CA 1 ATOM 2504 C C . LEU A 1 314 ? -10.213 34.496 29.615 1.00 9.45 ? 347 LEU A C 1 ATOM 2505 O O . LEU A 1 314 ? -9.955 34.130 30.753 1.00 8.81 ? 347 LEU A O 1 ATOM 2506 C CB . LEU A 1 314 ? -8.720 33.004 28.271 1.00 9.59 ? 347 LEU A CB 1 ATOM 2507 C CG . LEU A 1 314 ? -7.741 32.891 27.136 1.00 9.95 ? 347 LEU A CG 1 ATOM 2508 C CD1 . LEU A 1 314 ? -7.015 31.573 27.224 1.00 10.16 ? 347 LEU A CD1 1 ATOM 2509 C CD2 . LEU A 1 314 ? -8.409 33.076 25.766 1.00 9.82 ? 347 LEU A CD2 1 ATOM 2510 N N . LEU A 1 315 ? -11.424 34.893 29.243 1.00 8.90 ? 348 LEU A N 1 ATOM 2511 C CA . LEU A 1 315 ? -12.503 35.002 30.190 1.00 9.13 ? 348 LEU A CA 1 ATOM 2512 C C . LEU A 1 315 ? -13.389 33.781 30.243 1.00 9.02 ? 348 LEU A C 1 ATOM 2513 O O . LEU A 1 315 ? -13.909 33.453 31.274 1.00 8.89 ? 348 LEU A O 1 ATOM 2514 C CB . LEU A 1 315 ? -13.405 36.176 29.826 1.00 9.32 ? 348 LEU A CB 1 ATOM 2515 C CG . LEU A 1 315 ? -12.702 37.509 29.721 1.00 9.86 ? 348 LEU A CG 1 ATOM 2516 C CD1 . LEU A 1 315 ? -13.699 38.513 29.177 1.00 9.83 ? 348 LEU A CD1 1 ATOM 2517 C CD2 . LEU A 1 315 ? -12.124 37.907 31.097 1.00 9.83 ? 348 LEU A CD2 1 ATOM 2518 N N . ASP A 1 316 ? -13.645 33.169 29.110 1.00 8.95 ? 349 ASP A N 1 ATOM 2519 C CA . ASP A 1 316 ? -14.499 32.033 29.122 1.00 9.03 ? 349 ASP A CA 1 ATOM 2520 C C . ASP A 1 316 ? -14.324 31.205 27.864 1.00 8.84 ? 349 ASP A C 1 ATOM 2521 O O . ASP A 1 316 ? -13.591 31.568 26.930 1.00 7.69 ? 349 ASP A O 1 ATOM 2522 C CB . ASP A 1 316 ? -15.957 32.444 29.296 1.00 9.26 ? 349 ASP A CB 1 ATOM 2523 C CG . ASP A 1 316 ? -16.696 31.524 30.281 1.00 9.84 ? 349 ASP A CG 1 ATOM 2524 O OD1 . ASP A 1 316 ? -16.328 30.325 30.418 1.00 9.65 ? 349 ASP A OD1 1 ATOM 2525 O OD2 . ASP A 1 316 ? -17.643 31.996 30.935 1.00 10.23 -1 349 ASP A OD2 1 ATOM 2526 N N . MET A 1 317 ? -15.009 30.069 27.873 1.00 9.57 ? 350 MET A N 1 ATOM 2527 C CA . MET A 1 317 ? -15.107 29.237 26.666 1.00 10.58 ? 350 MET A CA 1 ATOM 2528 C C . MET A 1 317 ? -16.433 28.557 26.609 1.00 9.64 ? 350 MET A C 1 ATOM 2529 O O . MET A 1 317 ? -16.924 28.068 27.609 1.00 9.41 ? 350 MET A O 1 ATOM 2530 C CB . MET A 1 317 ? -14.015 28.193 26.646 1.00 11.96 ? 350 MET A CB 1 ATOM 2531 C CG . MET A 1 317 ? -13.955 27.469 25.331 1.00 13.41 ? 350 MET A CG 1 ATOM 2532 S SD . MET A 1 317 ? -14.429 25.778 25.523 1.00 15.35 ? 350 MET A SD 1 ATOM 2533 C CE . MET A 1 317 ? -12.868 25.276 26.193 1.00 15.10 ? 350 MET A CE 1 ATOM 2534 N N . LEU A 1 318 ? -17.003 28.553 25.418 1.00 9.08 ? 351 LEU A N 1 ATOM 2535 C CA . LEU A 1 318 ? -18.302 27.923 25.144 1.00 8.15 ? 351 LEU A CA 1 ATOM 2536 C C . LEU A 1 318 ? -18.060 26.759 24.220 1.00 7.22 ? 351 LEU A C 1 ATOM 2537 O O . LEU A 1 318 ? -17.517 26.962 23.154 1.00 6.77 ? 351 LEU A O 1 ATOM 2538 C CB . LEU A 1 318 ? -19.208 28.952 24.467 1.00 8.36 ? 351 LEU A CB 1 ATOM 2539 C CG . LEU A 1 318 ? -19.812 29.983 25.435 1.00 8.67 ? 351 LEU A CG 1 ATOM 2540 C CD1 . LEU A 1 318 ? -18.832 31.052 25.792 1.00 8.97 ? 351 LEU A CD1 1 ATOM 2541 C CD2 . LEU A 1 318 ? -21.032 30.669 24.846 1.00 9.07 ? 351 LEU A CD2 1 ATOM 2542 N N . GLN A 1 319 ? -18.476 25.556 24.620 1.00 6.71 ? 352 GLN A N 1 ATOM 2543 C CA . GLN A 1 319 ? -18.250 24.323 23.868 1.00 6.38 ? 352 GLN A CA 1 ATOM 2544 C C . GLN A 1 319 ? -19.510 23.877 23.279 1.00 6.49 ? 352 GLN A C 1 ATOM 2545 O O . GLN A 1 319 ? -20.471 23.707 23.987 1.00 6.87 ? 352 GLN A O 1 ATOM 2546 C CB . GLN A 1 319 ? -17.713 23.211 24.746 1.00 6.35 ? 352 GLN A CB 1 ATOM 2547 C CG . GLN A 1 319 ? -17.473 21.879 24.025 1.00 6.40 ? 352 GLN A CG 1 ATOM 2548 C CD . GLN A 1 319 ? -16.385 21.999 22.947 1.00 6.46 ? 352 GLN A CD 1 ATOM 2549 O OE1 . GLN A 1 319 ? -15.242 22.283 23.248 1.00 6.13 ? 352 GLN A OE1 1 ATOM 2550 N NE2 . GLN A 1 319 ? -16.760 21.821 21.680 1.00 6.61 ? 352 GLN A NE2 1 ATOM 2551 N N . TYR A 1 320 ? -19.535 23.696 21.973 1.00 6.72 ? 353 TYR A N 1 ATOM 2552 C CA . TYR A 1 320 ? -20.779 23.328 21.268 1.00 6.98 ? 353 TYR A CA 1 ATOM 2553 C C . TYR A 1 320 ? -20.593 21.972 20.675 1.00 7.01 ? 353 TYR A C 1 ATOM 2554 O O . TYR A 1 320 ? -19.477 21.583 20.368 1.00 6.88 ? 353 TYR A O 1 ATOM 2555 C CB . TYR A 1 320 ? -21.163 24.317 20.101 1.00 7.02 ? 353 TYR A CB 1 ATOM 2556 C CG . TYR A 1 320 ? -21.466 25.752 20.500 1.00 7.00 ? 353 TYR A CG 1 ATOM 2557 C CD1 . TYR A 1 320 ? -22.745 26.146 20.834 1.00 7.24 ? 353 TYR A CD1 1 ATOM 2558 C CD2 . TYR A 1 320 ? -20.465 26.697 20.571 1.00 7.14 ? 353 TYR A CD2 1 ATOM 2559 C CE1 . TYR A 1 320 ? -23.039 27.463 21.216 1.00 7.25 ? 353 TYR A CE1 1 ATOM 2560 C CE2 . TYR A 1 320 ? -20.736 28.016 20.916 1.00 7.32 ? 353 TYR A CE2 1 ATOM 2561 C CZ . TYR A 1 320 ? -22.035 28.388 21.246 1.00 7.45 ? 353 TYR A CZ 1 ATOM 2562 O OH . TYR A 1 320 ? -22.308 29.665 21.617 1.00 7.51 ? 353 TYR A OH 1 ATOM 2563 N N . TYR A 1 321 ? -21.699 21.270 20.469 1.00 7.13 ? 354 TYR A N 1 ATOM 2564 C CA . TYR A 1 321 ? -21.603 19.953 19.969 1.00 7.10 ? 354 TYR A CA 1 ATOM 2565 C C . TYR A 1 321 ? -22.815 19.588 19.211 1.00 7.66 ? 354 TYR A C 1 ATOM 2566 O O . TYR A 1 321 ? -23.870 20.227 19.350 1.00 7.88 ? 354 TYR A O 1 ATOM 2567 C CB . TYR A 1 321 ? -21.415 18.989 21.095 1.00 6.95 ? 354 TYR A CB 1 ATOM 2568 C CG . TYR A 1 321 ? -22.667 18.568 21.850 1.00 7.07 ? 354 TYR A CG 1 ATOM 2569 C CD1 . TYR A 1 321 ? -23.303 19.412 22.737 1.00 7.12 ? 354 TYR A CD1 1 ATOM 2570 C CD2 . TYR A 1 321 ? -23.192 17.300 21.708 1.00 7.16 ? 354 TYR A CD2 1 ATOM 2571 C CE1 . TYR A 1 321 ? -24.411 19.007 23.436 1.00 6.84 ? 354 TYR A CE1 1 ATOM 2572 C CE2 . TYR A 1 321 ? -24.292 16.896 22.420 1.00 6.87 ? 354 TYR A CE2 1 ATOM 2573 C CZ . TYR A 1 321 ? -24.874 17.764 23.279 1.00 6.83 ? 354 TYR A CZ 1 ATOM 2574 O OH . TYR A 1 321 ? -25.967 17.376 23.958 1.00 6.94 ? 354 TYR A OH 1 ATOM 2575 N N . LEU A 1 322 ? -22.656 18.509 18.441 1.00 8.17 ? 355 LEU A N 1 ATOM 2576 C CA . LEU A 1 322 ? -23.739 17.901 17.713 1.00 8.64 ? 355 LEU A CA 1 ATOM 2577 C C . LEU A 1 322 ? -23.959 16.525 18.290 1.00 9.11 ? 355 LEU A C 1 ATOM 2578 O O . LEU A 1 322 ? -23.048 15.710 18.314 1.00 8.86 ? 355 LEU A O 1 ATOM 2579 C CB . LEU A 1 322 ? -23.406 17.771 16.237 1.00 8.75 ? 355 LEU A CB 1 ATOM 2580 C CG . LEU A 1 322 ? -24.550 17.212 15.411 1.00 9.06 ? 355 LEU A CG 1 ATOM 2581 C CD1 . LEU A 1 322 ? -25.579 18.290 15.268 1.00 9.39 ? 355 LEU A CD1 1 ATOM 2582 C CD2 . LEU A 1 322 ? -24.152 16.801 14.020 1.00 9.41 ? 355 LEU A CD2 1 ATOM 2583 N N . ASN A 1 323 ? -25.164 16.283 18.799 1.00 9.80 ? 356 ASN A N 1 ATOM 2584 C CA . ASN A 1 323 ? -25.565 14.925 19.187 1.00 10.25 ? 356 ASN A CA 1 ATOM 2585 C C . ASN A 1 323 ? -25.799 14.153 17.904 1.00 10.20 ? 356 ASN A C 1 ATOM 2586 O O . ASN A 1 323 ? -26.861 14.223 17.256 1.00 10.17 ? 356 ASN A O 1 ATOM 2587 C CB . ASN A 1 323 ? -26.813 14.923 20.108 1.00 10.86 ? 356 ASN A CB 1 ATOM 2588 C CG . ASN A 1 323 ? -27.197 13.549 20.535 1.00 11.74 ? 356 ASN A CG 1 ATOM 2589 O OD1 . ASN A 1 323 ? -26.880 12.599 19.802 1.00 12.02 ? 356 ASN A OD1 1 ATOM 2590 N ND2 . ASN A 1 323 ? -27.879 13.398 21.719 1.00 13.14 ? 356 ASN A ND2 1 ATOM 2591 N N . LEU A 1 324 ? -24.759 13.454 17.529 1.00 10.17 ? 357 LEU A N 1 ATOM 2592 C CA . LEU A 1 324 ? -24.733 12.693 16.311 1.00 10.53 ? 357 LEU A CA 1 ATOM 2593 C C . LEU A 1 324 ? -25.903 11.764 16.162 1.00 10.65 ? 357 LEU A C 1 ATOM 2594 O O . LEU A 1 324 ? -26.518 11.691 15.129 1.00 11.45 ? 357 LEU A O 1 ATOM 2595 C CB . LEU A 1 324 ? -23.436 11.903 16.226 1.00 10.53 ? 357 LEU A CB 1 ATOM 2596 C CG . LEU A 1 324 ? -23.314 11.183 14.902 1.00 11.15 ? 357 LEU A CG 1 ATOM 2597 C CD1 . LEU A 1 324 ? -23.265 12.214 13.760 1.00 12.03 ? 357 LEU A CD1 1 ATOM 2598 C CD2 . LEU A 1 324 ? -22.046 10.388 14.896 1.00 11.58 ? 357 LEU A CD2 1 ATOM 2599 N N . THR A 1 325 ? -26.183 11.025 17.199 1.00 11.82 ? 358 THR A N 1 ATOM 2600 C CA . THR A 1 325 ? -27.250 10.071 17.189 1.00 12.79 ? 358 THR A CA 1 ATOM 2601 C C . THR A 1 325 ? -28.542 10.788 16.913 1.00 13.53 ? 358 THR A C 1 ATOM 2602 O O . THR A 1 325 ? -29.271 10.392 16.061 1.00 13.61 ? 358 THR A O 1 ATOM 2603 C CB . THR A 1 325 ? -27.324 9.361 18.525 1.00 12.86 ? 358 THR A CB 1 ATOM 2604 O OG1 . THR A 1 325 ? -26.186 8.539 18.633 1.00 13.30 ? 358 THR A OG1 1 ATOM 2605 C CG2 . THR A 1 325 ? -28.494 8.440 18.576 1.00 13.59 ? 358 THR A CG2 1 ATOM 2606 N N . GLU A 1 326 ? -28.785 11.882 17.617 1.00 14.79 ? 359 GLU A N 1 ATOM 2607 C CA . GLU A 1 326 ? -30.045 12.583 17.507 1.00 15.49 ? 359 GLU A CA 1 ATOM 2608 C C . GLU A 1 326 ? -30.204 13.121 16.097 1.00 14.49 ? 359 GLU A C 1 ATOM 2609 O O . GLU A 1 326 ? -31.270 13.033 15.513 1.00 15.40 ? 359 GLU A O 1 ATOM 2610 C CB . GLU A 1 326 ? -30.125 13.736 18.516 1.00 16.87 ? 359 GLU A CB 1 ATOM 2611 C CG . GLU A 1 326 ? -31.381 14.590 18.366 1.00 18.57 ? 359 GLU A CG 1 ATOM 2612 C CD . GLU A 1 326 ? -31.415 15.803 19.284 1.00 21.86 ? 359 GLU A CD 1 ATOM 2613 O OE1 . GLU A 1 326 ? -30.703 15.850 20.311 1.00 23.78 ? 359 GLU A OE1 1 ATOM 2614 O OE2 . GLU A 1 326 ? -32.153 16.753 18.974 1.00 27.16 -1 359 GLU A OE2 1 ATOM 2615 N N . ALA A 1 327 ? -29.137 13.681 15.571 1.00 13.24 ? 360 ALA A N 1 ATOM 2616 C CA . ALA A 1 327 ? -29.142 14.334 14.306 1.00 12.73 ? 360 ALA A CA 1 ATOM 2617 C C . ALA A 1 327 ? -29.422 13.362 13.219 1.00 13.42 ? 360 ALA A C 1 ATOM 2618 O O . ALA A 1 327 ? -30.232 13.649 12.328 1.00 14.20 ? 360 ALA A O 1 ATOM 2619 C CB . ALA A 1 327 ? -27.791 14.939 14.043 1.00 12.95 ? 360 ALA A CB 1 ATOM 2620 N N . ASN A 1 328 ? -28.748 12.221 13.238 1.00 12.81 ? 361 ASN A N 1 ATOM 2621 C CA . ASN A 1 328 ? -29.106 11.216 12.261 1.00 12.85 ? 361 ASN A CA 1 ATOM 2622 C C . ASN A 1 328 ? -30.503 10.642 12.447 1.00 14.46 ? 361 ASN A C 1 ATOM 2623 O O . ASN A 1 328 ? -31.134 10.296 11.459 1.00 15.36 ? 361 ASN A O 1 ATOM 2624 C CB . ASN A 1 328 ? -28.115 10.090 12.230 1.00 12.01 ? 361 ASN A CB 1 ATOM 2625 C CG . ASN A 1 328 ? -26.827 10.497 11.623 1.00 11.33 ? 361 ASN A CG 1 ATOM 2626 O OD1 . ASN A 1 328 ? -26.748 11.358 10.721 1.00 10.84 ? 361 ASN A OD1 1 ATOM 2627 N ND2 . ASN A 1 328 ? -25.802 9.892 12.102 1.00 11.05 ? 361 ASN A ND2 1 ATOM 2628 N N . LEU A 1 329 ? -30.988 10.480 13.674 1.00 15.56 ? 362 LEU A N 1 ATOM 2629 C CA . LEU A 1 329 ? -32.357 10.010 13.851 1.00 16.47 ? 362 LEU A CA 1 ATOM 2630 C C . LEU A 1 329 ? -33.322 10.977 13.189 1.00 18.52 ? 362 LEU A C 1 ATOM 2631 O O . LEU A 1 329 ? -34.227 10.546 12.502 1.00 18.52 ? 362 LEU A O 1 ATOM 2632 C CB . LEU A 1 329 ? -32.701 9.830 15.312 1.00 16.91 ? 362 LEU A CB 1 ATOM 2633 C CG . LEU A 1 329 ? -32.148 8.499 15.805 1.00 18.58 ? 362 LEU A CG 1 ATOM 2634 C CD1 . LEU A 1 329 ? -32.324 8.334 17.303 1.00 19.42 ? 362 LEU A CD1 1 ATOM 2635 C CD2 . LEU A 1 329 ? -32.806 7.337 15.096 1.00 19.56 ? 362 LEU A CD2 1 ATOM 2636 N N . LYS A 1 330 ? -33.100 12.281 13.333 1.00 20.54 ? 363 LYS A N 1 ATOM 2637 C CA . LYS A 1 330 ? -34.054 13.273 12.811 1.00 22.28 ? 363 LYS A CA 1 ATOM 2638 C C . LYS A 1 330 ? -33.665 13.799 11.447 1.00 21.18 ? 363 LYS A C 1 ATOM 2639 O O . LYS A 1 330 ? -34.372 14.570 10.859 1.00 22.03 ? 363 LYS A O 1 ATOM 2640 C CB . LYS A 1 330 ? -34.126 14.482 13.755 1.00 24.20 ? 363 LYS A CB 1 ATOM 2641 C CG . LYS A 1 330 ? -34.754 14.171 15.085 1.00 25.57 ? 363 LYS A CG 1 ATOM 2642 C CD . LYS A 1 330 ? -34.294 15.121 16.153 1.00 27.79 ? 363 LYS A CD 1 ATOM 2643 C CE . LYS A 1 330 ? -35.322 16.175 16.457 1.00 31.53 ? 363 LYS A CE 1 ATOM 2644 N NZ . LYS A 1 330 ? -34.902 16.969 17.656 1.00 34.38 1 363 LYS A NZ 1 ATOM 2645 N N . GLY A 1 331 ? -32.508 13.445 10.953 1.00 20.01 ? 364 GLY A N 1 ATOM 2646 C CA . GLY A 1 331 ? -32.014 14.183 9.814 1.00 20.15 ? 364 GLY A CA 1 ATOM 2647 C C . GLY A 1 331 ? -32.015 15.693 9.981 1.00 20.11 ? 364 GLY A C 1 ATOM 2648 O O . GLY A 1 331 ? -32.273 16.410 9.044 1.00 20.44 ? 364 GLY A O 1 ATOM 2649 N N . GLU A 1 332 ? -31.662 16.192 11.149 1.00 21.42 ? 365 GLU A N 1 ATOM 2650 C CA . GLU A 1 332 ? -31.519 17.640 11.335 1.00 21.92 ? 365 GLU A CA 1 ATOM 2651 C C . GLU A 1 332 ? -30.220 17.994 12.064 1.00 19.60 ? 365 GLU A C 1 ATOM 2652 O O . GLU A 1 332 ? -29.817 17.318 12.958 1.00 18.74 ? 365 GLU A O 1 ATOM 2653 C CB . GLU A 1 332 ? -32.711 18.194 12.117 1.00 23.66 ? 365 GLU A CB 1 ATOM 2654 C CG . GLU A 1 332 ? -34.070 17.992 11.479 1.00 26.74 ? 365 GLU A CG 1 ATOM 2655 C CD . GLU A 1 332 ? -34.333 18.892 10.256 1.00 31.53 ? 365 GLU A CD 1 ATOM 2656 O OE1 . GLU A 1 332 ? -33.636 19.936 10.075 1.00 34.16 ? 365 GLU A OE1 1 ATOM 2657 O OE2 . GLU A 1 332 ? -35.282 18.581 9.475 1.00 35.00 -1 365 GLU A OE2 1 ATOM 2658 N N . SER A 1 333 ? -29.596 19.080 11.667 1.00 20.28 ? 366 SER A N 1 ATOM 2659 C CA . SER A 1 333 ? -28.366 19.599 12.267 1.00 20.90 ? 366 SER A CA 1 ATOM 2660 C C . SER A 1 333 ? -28.562 20.291 13.565 1.00 21.39 ? 366 SER A C 1 ATOM 2661 O O . SER A 1 333 ? -28.380 21.470 13.598 1.00 23.14 ? 366 SER A O 1 ATOM 2662 C CB . SER A 1 333 ? -27.842 20.734 11.392 1.00 22.09 ? 366 SER A CB 1 ATOM 2663 O OG . SER A 1 333 ? -27.034 20.200 10.413 1.00 26.78 ? 366 SER A OG 1 ATOM 2664 N N . ILE A 1 334 ? -28.891 19.627 14.653 1.00 23.42 ? 367 ILE A N 1 ATOM 2665 C CA . ILE A 1 334 ? -29.080 20.379 15.893 1.00 22.90 ? 367 ILE A CA 1 ATOM 2666 C C . ILE A 1 334 ? -27.762 20.541 16.648 1.00 19.32 ? 367 ILE A C 1 ATOM 2667 O O . ILE A 1 334 ? -27.404 19.692 17.431 1.00 21.71 ? 367 ILE A O 1 ATOM 2668 C CB . ILE A 1 334 ? -30.106 19.729 16.841 1.00 25.91 ? 367 ILE A CB 1 ATOM 2669 C CG1 . ILE A 1 334 ? -31.163 18.928 16.085 1.00 27.44 ? 367 ILE A CG1 1 ATOM 2670 C CG2 . ILE A 1 334 ? -30.797 20.815 17.661 1.00 27.51 ? 367 ILE A CG2 1 ATOM 2671 C CD1 . ILE A 1 334 ? -32.023 19.788 15.216 1.00 28.04 ? 367 ILE A CD1 1 ATOM 2672 N N . TRP A 1 335 ? -27.043 21.619 16.397 1.00 16.30 ? 368 TRP A N 1 ATOM 2673 C CA . TRP A 1 335 ? -25.891 22.008 17.213 1.00 14.29 ? 368 TRP A CA 1 ATOM 2674 C C . TRP A 1 335 ? -26.352 22.630 18.525 1.00 13.99 ? 368 TRP A C 1 ATOM 2675 O O . TRP A 1 335 ? -27.306 23.402 18.541 1.00 14.57 ? 368 TRP A O 1 ATOM 2676 C CB . TRP A 1 335 ? -25.003 22.959 16.446 1.00 13.86 ? 368 TRP A CB 1 ATOM 2677 C CG . TRP A 1 335 ? -24.219 22.236 15.384 1.00 13.05 ? 368 TRP A CG 1 ATOM 2678 C CD1 . TRP A 1 335 ? -24.608 21.981 14.118 1.00 13.39 ? 368 TRP A CD1 1 ATOM 2679 C CD2 . TRP A 1 335 ? -22.927 21.680 15.524 1.00 11.96 ? 368 TRP A CD2 1 ATOM 2680 N NE1 . TRP A 1 335 ? -23.618 21.286 13.434 1.00 12.55 ? 368 TRP A NE1 1 ATOM 2681 C CE2 . TRP A 1 335 ? -22.577 21.098 14.288 1.00 11.81 ? 368 TRP A CE2 1 ATOM 2682 C CE3 . TRP A 1 335 ? -22.019 21.602 16.590 1.00 11.49 ? 368 TRP A CE3 1 ATOM 2683 C CZ2 . TRP A 1 335 ? -21.382 20.459 14.085 1.00 11.31 ? 368 TRP A CZ2 1 ATOM 2684 C CZ3 . TRP A 1 335 ? -20.828 20.960 16.383 1.00 11.09 ? 368 TRP A CZ3 1 ATOM 2685 C CH2 . TRP A 1 335 ? -20.523 20.393 15.134 1.00 11.25 ? 368 TRP A CH2 1 ATOM 2686 N N . LYS A 1 336 ? -25.718 22.244 19.634 1.00 12.68 ? 369 LYS A N 1 ATOM 2687 C CA . LYS A 1 336 ? -26.111 22.696 20.929 1.00 11.87 ? 369 LYS A CA 1 ATOM 2688 C C . LYS A 1 336 ? -24.933 23.106 21.772 1.00 11.48 ? 369 LYS A C 1 ATOM 2689 O O . LYS A 1 336 ? -23.791 22.597 21.573 1.00 10.98 ? 369 LYS A O 1 ATOM 2690 C CB . LYS A 1 336 ? -26.753 21.563 21.686 1.00 12.44 ? 369 LYS A CB 1 ATOM 2691 C CG . LYS A 1 336 ? -27.944 20.961 21.021 1.00 13.50 ? 369 LYS A CG 1 ATOM 2692 C CD . LYS A 1 336 ? -28.425 19.759 21.812 1.00 14.00 ? 369 LYS A CD 1 ATOM 2693 C CE . LYS A 1 336 ? -29.729 19.256 21.247 1.00 15.08 ? 369 LYS A CE 1 ATOM 2694 N NZ . LYS A 1 336 ? -30.117 17.961 21.868 1.00 16.50 1 369 LYS A NZ 1 ATOM 2695 N N . LEU A 1 337 ? -25.253 23.919 22.786 1.00 10.48 ? 370 LEU A N 1 ATOM 2696 C CA . LEU A 1 337 ? -24.312 24.316 23.802 1.00 10.36 ? 370 LEU A CA 1 ATOM 2697 C C . LEU A 1 337 ? -24.097 23.148 24.728 1.00 9.53 ? 370 LEU A C 1 ATOM 2698 O O . LEU A 1 337 ? -25.006 22.666 25.282 1.00 9.53 ? 370 LEU A O 1 ATOM 2699 C CB . LEU A 1 337 ? -24.859 25.498 24.606 1.00 11.24 ? 370 LEU A CB 1 ATOM 2700 C CG . LEU A 1 337 ? -23.984 26.083 25.732 1.00 11.59 ? 370 LEU A CG 1 ATOM 2701 C CD1 . LEU A 1 337 ? -22.696 26.662 25.164 1.00 11.73 ? 370 LEU A CD1 1 ATOM 2702 C CD2 . LEU A 1 337 ? -24.703 27.160 26.490 1.00 11.91 ? 370 LEU A CD2 1 ATOM 2703 N N . GLU A 1 338 ? -22.870 22.679 24.893 1.00 9.17 ? 371 GLU A N 1 ATOM 2704 C CA . GLU A 1 338 ? -22.582 21.605 25.854 1.00 8.48 ? 371 GLU A CA 1 ATOM 2705 C C . GLU A 1 338 ? -22.363 22.211 27.213 1.00 7.92 ? 371 GLU A C 1 ATOM 2706 O O . GLU A 1 338 ? -22.863 21.726 28.178 1.00 6.93 ? 371 GLU A O 1 ATOM 2707 C CB . GLU A 1 338 ? -21.314 20.832 25.432 1.00 8.42 ? 371 GLU A CB 1 ATOM 2708 C CG . GLU A 1 338 ? -21.201 19.440 26.047 1.00 8.33 ? 371 GLU A CG 1 ATOM 2709 C CD . GLU A 1 338 ? -19.822 18.732 25.857 1.00 8.18 ? 371 GLU A CD 1 ATOM 2710 O OE1 . GLU A 1 338 ? -18.790 19.376 25.555 1.00 7.65 ? 371 GLU A OE1 1 ATOM 2711 O OE2 . GLU A 1 338 ? -19.784 17.492 26.044 1.00 8.04 -1 371 GLU A OE2 1 ATOM 2712 N N . TYR A 1 339 ? -21.496 23.217 27.256 1.00 8.27 ? 372 TYR A N 1 ATOM 2713 C CA . TYR A 1 339 ? -21.207 23.942 28.468 1.00 8.76 ? 372 TYR A CA 1 ATOM 2714 C C . TYR A 1 339 ? -20.584 25.307 28.183 1.00 8.87 ? 372 TYR A C 1 ATOM 2715 O O . TYR A 1 339 ? -20.053 25.553 27.090 1.00 8.40 ? 372 TYR A O 1 ATOM 2716 C CB . TYR A 1 339 ? -20.297 23.136 29.429 1.00 8.84 ? 372 TYR A CB 1 ATOM 2717 C CG . TYR A 1 339 ? -18.894 22.870 28.922 1.00 9.70 ? 372 TYR A CG 1 ATOM 2718 C CD1 . TYR A 1 339 ? -17.890 23.787 29.079 1.00 10.08 ? 372 TYR A CD1 1 ATOM 2719 C CD2 . TYR A 1 339 ? -18.572 21.683 28.272 1.00 10.12 ? 372 TYR A CD2 1 ATOM 2720 C CE1 . TYR A 1 339 ? -16.600 23.541 28.610 1.00 10.40 ? 372 TYR A CE1 1 ATOM 2721 C CE2 . TYR A 1 339 ? -17.275 21.434 27.824 1.00 10.31 ? 372 TYR A CE2 1 ATOM 2722 C CZ . TYR A 1 339 ? -16.287 22.367 27.996 1.00 10.14 ? 372 TYR A CZ 1 ATOM 2723 O OH . TYR A 1 339 ? -14.989 22.130 27.567 1.00 9.58 ? 372 TYR A OH 1 ATOM 2724 N N . ILE A 1 340 ? -20.685 26.158 29.207 1.00 8.78 ? 373 ILE A N 1 ATOM 2725 C CA . ILE A 1 340 ? -19.945 27.368 29.356 1.00 9.21 ? 373 ILE A CA 1 ATOM 2726 C C . ILE A 1 340 ? -18.976 27.080 30.502 1.00 9.66 ? 373 ILE A C 1 ATOM 2727 O O . ILE A 1 340 ? -19.399 26.787 31.583 1.00 10.23 ? 373 ILE A O 1 ATOM 2728 C CB . ILE A 1 340 ? -20.891 28.479 29.788 1.00 9.60 ? 373 ILE A CB 1 ATOM 2729 C CG1 . ILE A 1 340 ? -21.961 28.662 28.734 1.00 10.06 ? 373 ILE A CG1 1 ATOM 2730 C CG2 . ILE A 1 340 ? -20.163 29.784 30.041 1.00 9.77 ? 373 ILE A CG2 1 ATOM 2731 C CD1 . ILE A 1 340 ? -23.098 29.558 29.193 1.00 10.39 ? 373 ILE A CD1 1 ATOM 2732 N N . LEU A 1 341 ? -17.680 27.213 30.286 1.00 10.03 ? 374 LEU A N 1 ATOM 2733 C CA . LEU A 1 341 ? -16.702 26.676 31.191 1.00 9.95 ? 374 LEU A CA 1 ATOM 2734 C C . LEU A 1 341 ? -16.772 27.277 32.603 1.00 10.28 ? 374 LEU A C 1 ATOM 2735 O O . LEU A 1 341 ? -16.732 26.509 33.568 1.00 11.17 ? 374 LEU A O 1 ATOM 2736 C CB . LEU A 1 341 ? -15.321 26.848 30.602 1.00 9.93 ? 374 LEU A CB 1 ATOM 2737 C CG . LEU A 1 341 ? -14.279 25.919 31.195 1.00 10.32 ? 374 LEU A CG 1 ATOM 2738 C CD1 . LEU A 1 341 ? -13.052 25.837 30.337 1.00 10.50 ? 374 LEU A CD1 1 ATOM 2739 C CD2 . LEU A 1 341 ? -13.825 26.461 32.519 1.00 11.06 ? 374 LEU A CD2 1 ATOM 2740 N N . THR A 1 342 ? -16.861 28.596 32.748 1.00 10.09 ? 375 THR A N 1 ATOM 2741 C CA . THR A 1 342 ? -16.955 29.203 34.072 1.00 10.40 ? 375 THR A CA 1 ATOM 2742 C C . THR A 1 342 ? -18.235 28.875 34.778 1.00 12.04 ? 375 THR A C 1 ATOM 2743 O O . THR A 1 342 ? -18.217 28.745 35.999 1.00 13.64 ? 375 THR A O 1 ATOM 2744 C CB . THR A 1 342 ? -16.792 30.748 34.125 1.00 9.94 ? 375 THR A CB 1 ATOM 2745 O OG1 . THR A 1 342 ? -17.773 31.419 33.357 1.00 9.02 ? 375 THR A OG1 1 ATOM 2746 C CG2 . THR A 1 342 ? -15.433 31.173 33.670 1.00 9.94 ? 375 THR A CG2 1 ATOM 2747 N N . GLN A 1 343 ? -19.330 28.706 34.062 1.00 13.40 ? 376 GLN A N 1 ATOM 2748 C CA . GLN A 1 343 ? -20.551 28.247 34.706 1.00 15.38 ? 376 GLN A CA 1 ATOM 2749 C C . GLN A 1 343 ? -20.519 26.800 35.171 1.00 13.44 ? 376 GLN A C 1 ATOM 2750 O O . GLN A 1 343 ? -20.967 26.541 36.250 1.00 14.18 ? 376 GLN A O 1 ATOM 2751 C CB . GLN A 1 343 ? -21.808 28.372 33.817 1.00 19.08 ? 376 GLN A CB 1 ATOM 2752 C CG . GLN A 1 343 ? -22.259 29.777 33.447 1.00 23.96 ? 376 GLN A CG 1 ATOM 2753 C CD . GLN A 1 343 ? -22.683 30.625 34.654 1.00 28.94 ? 376 GLN A CD 1 ATOM 2754 O OE1 . GLN A 1 343 ? -23.586 30.244 35.450 1.00 34.29 ? 376 GLN A OE1 1 ATOM 2755 N NE2 . GLN A 1 343 ? -22.017 31.774 34.815 1.00 29.91 ? 376 GLN A NE2 1 ATOM 2756 N N . THR A 1 344 ? -20.130 25.829 34.369 1.00 12.11 ? 377 THR A N 1 ATOM 2757 C CA . THR A 1 344 ? -20.327 24.471 34.849 1.00 12.28 ? 377 THR A CA 1 ATOM 2758 C C . THR A 1 344 ? -19.392 24.182 35.988 1.00 11.45 ? 377 THR A C 1 ATOM 2759 O O . THR A 1 344 ? -19.713 23.353 36.771 1.00 11.20 ? 377 THR A O 1 ATOM 2760 C CB . THR A 1 344 ? -20.004 23.300 33.880 1.00 12.66 ? 377 THR A CB 1 ATOM 2761 O OG1 . THR A 1 344 ? -19.219 23.742 32.784 1.00 13.09 ? 377 THR A OG1 1 ATOM 2762 C CG2 . THR A 1 344 ? -21.189 22.529 33.470 1.00 12.69 ? 377 THR A CG2 1 ATOM 2763 N N . TYR A 1 345 ? -18.210 24.777 35.995 1.00 11.05 ? 378 TYR A N 1 ATOM 2764 C CA . TYR A 1 345 ? -17.227 24.510 37.006 1.00 11.79 ? 378 TYR A CA 1 ATOM 2765 C C . TYR A 1 345 ? -17.141 25.602 38.090 1.00 14.27 ? 378 TYR A C 1 ATOM 2766 O O . TYR A 1 345 ? -16.405 25.453 39.047 1.00 13.93 ? 378 TYR A O 1 ATOM 2767 C CB . TYR A 1 345 ? -15.873 24.339 36.352 1.00 10.98 ? 378 TYR A CB 1 ATOM 2768 C CG . TYR A 1 345 ? -15.699 23.098 35.448 1.00 10.28 ? 378 TYR A CG 1 ATOM 2769 C CD1 . TYR A 1 345 ? -15.868 21.831 35.918 1.00 9.80 ? 378 TYR A CD1 1 ATOM 2770 C CD2 . TYR A 1 345 ? -15.307 23.241 34.134 1.00 9.75 ? 378 TYR A CD2 1 ATOM 2771 C CE1 . TYR A 1 345 ? -15.678 20.728 35.080 1.00 9.87 ? 378 TYR A CE1 1 ATOM 2772 C CE2 . TYR A 1 345 ? -15.112 22.180 33.310 1.00 9.42 ? 378 TYR A CE2 1 ATOM 2773 C CZ . TYR A 1 345 ? -15.302 20.912 33.751 1.00 9.53 ? 378 TYR A CZ 1 ATOM 2774 O OH . TYR A 1 345 ? -15.085 19.863 32.863 1.00 8.43 ? 378 TYR A OH 1 ATOM 2775 N N . ASP A 1 346 ? -17.882 26.699 37.956 1.00 17.67 ? 379 ASP A N 1 ATOM 2776 C CA . ASP A 1 346 ? -17.801 27.774 38.941 1.00 22.45 ? 379 ASP A CA 1 ATOM 2777 C C . ASP A 1 346 ? -16.386 28.213 39.299 1.00 20.19 ? 379 ASP A C 1 ATOM 2778 O O . ASP A 1 346 ? -15.917 28.008 40.390 1.00 22.57 ? 379 ASP A O 1 ATOM 2779 C CB . ASP A 1 346 ? -18.558 27.370 40.220 1.00 28.18 ? 379 ASP A CB 1 ATOM 2780 C CG . ASP A 1 346 ? -20.009 26.993 39.931 1.00 34.66 ? 379 ASP A CG 1 ATOM 2781 O OD1 . ASP A 1 346 ? -20.673 27.656 39.060 1.00 43.65 ? 379 ASP A OD1 1 ATOM 2782 O OD2 . ASP A 1 346 ? -20.483 26.023 40.555 1.00 37.69 -1 379 ASP A OD2 1 ATOM 2783 N N . ILE A 1 347 ? -15.722 28.829 38.348 1.00 19.20 ? 380 ILE A N 1 ATOM 2784 C CA . ILE A 1 347 ? -14.413 29.414 38.531 1.00 16.71 ? 380 ILE A CA 1 ATOM 2785 C C . ILE A 1 347 ? -14.512 30.749 37.849 1.00 16.61 ? 380 ILE A C 1 ATOM 2786 O O . ILE A 1 347 ? -15.408 31.000 37.091 1.00 15.94 ? 380 ILE A O 1 ATOM 2787 C CB . ILE A 1 347 ? -13.315 28.585 37.886 1.00 16.86 ? 380 ILE A CB 1 ATOM 2788 C CG1 . ILE A 1 347 ? -13.614 28.309 36.409 1.00 17.39 ? 380 ILE A CG1 1 ATOM 2789 C CG2 . ILE A 1 347 ? -13.163 27.299 38.636 1.00 17.08 ? 380 ILE A CG2 1 ATOM 2790 C CD1 . ILE A 1 347 ? -12.437 27.710 35.672 1.00 18.00 ? 380 ILE A CD1 1 ATOM 2791 N N . GLU A 1 348 ? -13.611 31.635 38.147 1.00 19.57 ? 381 GLU A N 1 ATOM 2792 C CA . GLU A 1 348 ? -13.793 33.002 37.749 1.00 22.85 ? 381 GLU A CA 1 ATOM 2793 C C . GLU A 1 348 ? -13.513 33.206 36.296 1.00 18.81 ? 381 GLU A C 1 ATOM 2794 O O . GLU A 1 348 ? -14.143 34.022 35.696 1.00 18.18 ? 381 GLU A O 1 ATOM 2795 C CB . GLU A 1 348 ? -12.908 33.935 38.589 1.00 30.48 ? 381 GLU A CB 1 ATOM 2796 C CG . GLU A 1 348 ? -13.236 33.937 40.080 1.00 39.74 ? 381 GLU A CG 1 ATOM 2797 C CD . GLU A 1 348 ? -14.559 34.655 40.391 1.00 49.86 ? 381 GLU A CD 1 ATOM 2798 O OE1 . GLU A 1 348 ? -14.581 35.913 40.455 1.00 59.98 ? 381 GLU A OE1 1 ATOM 2799 O OE2 . GLU A 1 348 ? -15.585 33.961 40.582 1.00 55.78 -1 381 GLU A OE2 1 ATOM 2800 N N . ASP A 1 349 ? -12.531 32.498 35.750 1.00 17.06 ? 382 ASP A N 1 ATOM 2801 C CA . ASP A 1 349 ? -12.054 32.746 34.394 1.00 16.31 ? 382 ASP A CA 1 ATOM 2802 C C . ASP A 1 349 ? -11.109 31.628 33.992 1.00 13.88 ? 382 ASP A C 1 ATOM 2803 O O . ASP A 1 349 ? -10.972 30.691 34.721 1.00 13.39 ? 382 ASP A O 1 ATOM 2804 C CB . ASP A 1 349 ? -11.306 34.093 34.357 1.00 17.43 ? 382 ASP A CB 1 ATOM 2805 C CG . ASP A 1 349 ? -10.132 34.117 35.313 1.00 19.92 ? 382 ASP A CG 1 ATOM 2806 O OD1 . ASP A 1 349 ? -9.556 33.036 35.627 1.00 21.40 ? 382 ASP A OD1 1 ATOM 2807 O OD2 . ASP A 1 349 ? -9.757 35.225 35.770 1.00 23.61 -1 382 ASP A OD2 1 ATOM 2808 N N . LEU A 1 350 ? -10.387 31.778 32.895 1.00 12.31 ? 383 LEU A N 1 ATOM 2809 C CA . LEU A 1 350 ? -9.517 30.752 32.400 1.00 12.02 ? 383 LEU A CA 1 ATOM 2810 C C . LEU A 1 350 ? -8.033 30.964 32.683 1.00 12.82 ? 383 LEU A C 1 ATOM 2811 O O . LEU A 1 350 ? -7.184 30.297 32.066 1.00 11.89 ? 383 LEU A O 1 ATOM 2812 C CB . LEU A 1 350 ? -9.732 30.590 30.911 1.00 11.66 ? 383 LEU A CB 1 ATOM 2813 C CG . LEU A 1 350 ? -10.978 29.793 30.510 1.00 11.52 ? 383 LEU A CG 1 ATOM 2814 C CD1 . LEU A 1 350 ? -12.249 30.155 31.229 1.00 11.27 ? 383 LEU A CD1 1 ATOM 2815 C CD2 . LEU A 1 350 ? -11.166 29.853 29.012 1.00 11.41 ? 383 LEU A CD2 1 ATOM 2816 N N . GLN A 1 351 ? -7.707 31.805 33.664 1.00 13.96 ? 384 GLN A N 1 ATOM 2817 C CA . GLN A 1 351 ? -6.307 32.026 33.996 1.00 15.58 ? 384 GLN A CA 1 ATOM 2818 C C . GLN A 1 351 ? -5.770 30.776 34.616 1.00 14.10 ? 384 GLN A C 1 ATOM 2819 O O . GLN A 1 351 ? -6.518 30.024 35.217 1.00 13.58 ? 384 GLN A O 1 ATOM 2820 C CB . GLN A 1 351 ? -6.082 33.082 35.073 1.00 19.15 ? 384 GLN A CB 1 ATOM 2821 C CG . GLN A 1 351 ? -6.964 34.272 35.050 1.00 24.06 ? 384 GLN A CG 1 ATOM 2822 C CD . GLN A 1 351 ? -6.240 35.547 34.748 1.00 27.47 ? 384 GLN A CD 1 ATOM 2823 O OE1 . GLN A 1 351 ? -5.476 35.611 33.801 1.00 29.91 ? 384 GLN A OE1 1 ATOM 2824 N NE2 . GLN A 1 351 ? -6.550 36.597 35.505 1.00 28.29 ? 384 GLN A NE2 1 ATOM 2825 N N . PRO A 1 352 ? -4.455 30.629 34.604 1.00 13.23 ? 385 PRO A N 1 ATOM 2826 C CA . PRO A 1 352 ? -3.842 29.454 35.139 1.00 13.94 ? 385 PRO A CA 1 ATOM 2827 C C . PRO A 1 352 ? -4.233 29.142 36.577 1.00 15.22 ? 385 PRO A C 1 ATOM 2828 O O . PRO A 1 352 ? -4.507 28.016 36.893 1.00 16.02 ? 385 PRO A O 1 ATOM 2829 C CB . PRO A 1 352 ? -2.344 29.761 35.054 1.00 13.90 ? 385 PRO A CB 1 ATOM 2830 C CG . PRO A 1 352 ? -2.187 30.834 34.046 1.00 13.19 ? 385 PRO A CG 1 ATOM 2831 C CD . PRO A 1 352 ? -3.511 31.486 33.877 1.00 12.82 ? 385 PRO A CD 1 ATOM 2832 N N . GLU A 1 353 ? -4.241 30.131 37.439 1.00 16.74 ? 386 GLU A N 1 ATOM 2833 C CA . GLU A 1 353 ? -4.557 29.906 38.849 1.00 17.40 ? 386 GLU A CA 1 ATOM 2834 C C . GLU A 1 353 ? -5.949 29.333 38.988 1.00 15.21 ? 386 GLU A C 1 ATOM 2835 O O . GLU A 1 353 ? -6.155 28.435 39.788 1.00 14.51 ? 386 GLU A O 1 ATOM 2836 C CB . GLU A 1 353 ? -4.485 31.219 39.628 1.00 21.13 ? 386 GLU A CB 1 ATOM 2837 C CG . GLU A 1 353 ? -3.312 32.159 39.266 1.00 25.99 ? 386 GLU A CG 1 ATOM 2838 C CD . GLU A 1 353 ? -3.557 33.025 38.004 1.00 29.27 ? 386 GLU A CD 1 ATOM 2839 O OE1 . GLU A 1 353 ? -4.594 33.746 37.978 1.00 36.79 ? 386 GLU A OE1 1 ATOM 2840 O OE2 . GLU A 1 353 ? -2.709 33.002 37.054 1.00 29.30 -1 386 GLU A OE2 1 ATOM 2841 N N . SER A 1 354 ? -6.911 29.842 38.217 1.00 14.12 ? 387 SER A N 1 ATOM 2842 C CA . SER A 1 354 ? -8.275 29.272 38.190 1.00 13.65 ? 387 SER A CA 1 ATOM 2843 C C . SER A 1 354 ? -8.326 27.829 37.677 1.00 13.87 ? 387 SER A C 1 ATOM 2844 O O . SER A 1 354 ? -8.935 27.000 38.280 1.00 14.90 ? 387 SER A O 1 ATOM 2845 C CB . SER A 1 354 ? -9.202 30.075 37.324 1.00 13.13 ? 387 SER A CB 1 ATOM 2846 O OG . SER A 1 354 ? -9.203 31.400 37.683 1.00 13.26 ? 387 SER A OG 1 ATOM 2847 N N . LEU A 1 355 ? -7.689 27.520 36.568 1.00 14.27 ? 388 LEU A N 1 ATOM 2848 C CA . LEU A 1 355 ? -7.695 26.144 36.090 1.00 15.24 ? 388 LEU A CA 1 ATOM 2849 C C . LEU A 1 355 ? -6.995 25.185 37.054 1.00 15.44 ? 388 LEU A C 1 ATOM 2850 O O . LEU A 1 355 ? -7.456 24.020 37.244 1.00 14.64 ? 388 LEU A O 1 ATOM 2851 C CB . LEU A 1 355 ? -6.999 26.040 34.740 1.00 15.91 ? 388 LEU A CB 1 ATOM 2852 C CG . LEU A 1 355 ? -7.667 26.757 33.571 1.00 16.08 ? 388 LEU A CG 1 ATOM 2853 C CD1 . LEU A 1 355 ? -6.987 26.296 32.283 1.00 16.52 ? 388 LEU A CD1 1 ATOM 2854 C CD2 . LEU A 1 355 ? -9.144 26.450 33.558 1.00 15.62 ? 388 LEU A CD2 1 ATOM 2855 N N . TYR A 1 356 ? -5.899 25.662 37.649 1.00 15.18 ? 389 TYR A N 1 ATOM 2856 C CA . TYR A 1 356 ? -5.169 24.895 38.646 1.00 17.18 ? 389 TYR A CA 1 ATOM 2857 C C . TYR A 1 356 ? -6.066 24.506 39.829 1.00 14.95 ? 389 TYR A C 1 ATOM 2858 O O . TYR A 1 356 ? -6.124 23.337 40.193 1.00 13.17 ? 389 TYR A O 1 ATOM 2859 C CB . TYR A 1 356 ? -3.974 25.668 39.160 1.00 21.38 ? 389 TYR A CB 1 ATOM 2860 C CG . TYR A 1 356 ? -3.062 24.819 39.981 1.00 26.08 ? 389 TYR A CG 1 ATOM 2861 C CD1 . TYR A 1 356 ? -2.342 23.805 39.379 1.00 30.49 ? 389 TYR A CD1 1 ATOM 2862 C CD2 . TYR A 1 356 ? -2.930 25.016 41.346 1.00 30.50 ? 389 TYR A CD2 1 ATOM 2863 C CE1 . TYR A 1 356 ? -1.487 23.011 40.097 1.00 34.51 ? 389 TYR A CE1 1 ATOM 2864 C CE2 . TYR A 1 356 ? -2.083 24.219 42.096 1.00 36.62 ? 389 TYR A CE2 1 ATOM 2865 C CZ . TYR A 1 356 ? -1.365 23.213 41.452 1.00 39.48 ? 389 TYR A CZ 1 ATOM 2866 O OH . TYR A 1 356 ? -0.513 22.374 42.141 1.00 55.26 ? 389 TYR A OH 1 ATOM 2867 N N . GLY A 1 357 ? -6.791 25.491 40.360 1.00 13.63 ? 390 GLY A N 1 ATOM 2868 C CA . GLY A 1 357 ? -7.828 25.270 41.357 1.00 12.78 ? 390 GLY A CA 1 ATOM 2869 C C . GLY A 1 357 ? -8.848 24.236 40.918 1.00 12.90 ? 390 GLY A C 1 ATOM 2870 O O . GLY A 1 357 ? -9.209 23.318 41.680 1.00 12.34 ? 390 GLY A O 1 ATOM 2871 N N . LEU A 1 358 ? -9.337 24.355 39.683 1.00 12.85 ? 391 LEU A N 1 ATOM 2872 C CA . LEU A 1 358 ? -10.280 23.343 39.179 1.00 12.75 ? 391 LEU A CA 1 ATOM 2873 C C . LEU A 1 358 ? -9.669 21.926 39.181 1.00 12.39 ? 391 LEU A C 1 ATOM 2874 O O . LEU A 1 358 ? -10.307 20.993 39.583 1.00 11.50 ? 391 LEU A O 1 ATOM 2875 C CB . LEU A 1 358 ? -10.753 23.689 37.767 1.00 12.63 ? 391 LEU A CB 1 ATOM 2876 C CG . LEU A 1 358 ? -11.792 22.731 37.188 1.00 11.93 ? 391 LEU A CG 1 ATOM 2877 C CD1 . LEU A 1 358 ? -13.010 22.580 38.083 1.00 11.88 ? 391 LEU A CD1 1 ATOM 2878 C CD2 . LEU A 1 358 ? -12.216 23.178 35.826 1.00 11.55 ? 391 LEU A CD2 1 ATOM 2879 N N . ALA A 1 359 ? -8.422 21.791 38.735 1.00 12.60 ? 392 ALA A N 1 ATOM 2880 C CA . ALA A 1 359 ? -7.774 20.495 38.704 1.00 12.31 ? 392 ALA A CA 1 ATOM 2881 C C . ALA A 1 359 ? -7.604 19.920 40.095 1.00 12.82 ? 392 ALA A C 1 ATOM 2882 O O . ALA A 1 359 ? -7.761 18.716 40.305 1.00 12.60 ? 392 ALA A O 1 ATOM 2883 C CB . ALA A 1 359 ? -6.446 20.601 38.006 1.00 11.82 ? 392 ALA A CB 1 ATOM 2884 N N . LYS A 1 360 ? -7.294 20.777 41.055 1.00 14.13 ? 393 LYS A N 1 ATOM 2885 C CA . LYS A 1 360 ? -7.219 20.347 42.457 1.00 15.16 ? 393 LYS A CA 1 ATOM 2886 C C . LYS A 1 360 ? -8.522 19.762 42.943 1.00 14.54 ? 393 LYS A C 1 ATOM 2887 O O . LYS A 1 360 ? -8.519 18.698 43.522 1.00 13.66 ? 393 LYS A O 1 ATOM 2888 C CB . LYS A 1 360 ? -6.856 21.502 43.333 1.00 16.31 ? 393 LYS A CB 1 ATOM 2889 C CG . LYS A 1 360 ? -5.416 21.905 43.154 1.00 18.78 ? 393 LYS A CG 1 ATOM 2890 C CD . LYS A 1 360 ? -4.535 20.722 43.460 1.00 21.45 ? 393 LYS A CD 1 ATOM 2891 C CE . LYS A 1 360 ? -3.194 21.130 44.032 1.00 24.75 ? 393 LYS A CE 1 ATOM 2892 N NZ . LYS A 1 360 ? -2.426 19.841 44.105 1.00 27.39 1 393 LYS A NZ 1 ATOM 2893 N N . GLN A 1 361 ? -9.620 20.446 42.669 1.00 13.62 ? 394 GLN A N 1 ATOM 2894 C CA . GLN A 1 361 ? -10.928 19.887 42.897 1.00 14.48 ? 394 GLN A CA 1 ATOM 2895 C C . GLN A 1 361 ? -11.180 18.518 42.288 1.00 13.68 ? 394 GLN A C 1 ATOM 2896 O O . GLN A 1 361 ? -11.869 17.708 42.922 1.00 13.56 ? 394 GLN A O 1 ATOM 2897 C CB . GLN A 1 361 ? -12.032 20.834 42.403 1.00 17.01 ? 394 GLN A CB 1 ATOM 2898 C CG . GLN A 1 361 ? -12.135 22.136 43.171 1.00 19.65 ? 394 GLN A CG 1 ATOM 2899 C CD . GLN A 1 361 ? -13.386 22.869 42.802 1.00 25.65 ? 394 GLN A CD 1 ATOM 2900 O OE1 . GLN A 1 361 ? -13.349 23.826 42.046 1.00 29.16 ? 394 GLN A OE1 1 ATOM 2901 N NE2 . GLN A 1 361 ? -14.539 22.397 43.313 1.00 31.25 ? 394 GLN A NE2 1 ATOM 2902 N N . PHE A 1 362 ? -10.659 18.249 41.078 1.00 12.21 ? 395 PHE A N 1 ATOM 2903 C CA . PHE A 1 362 ? -10.797 16.926 40.466 1.00 11.25 ? 395 PHE A CA 1 ATOM 2904 C C . PHE A 1 362 ? -10.173 15.828 41.314 1.00 11.51 ? 395 PHE A C 1 ATOM 2905 O O . PHE A 1 362 ? -10.619 14.684 41.251 1.00 10.87 ? 395 PHE A O 1 ATOM 2906 C CB . PHE A 1 362 ? -10.143 16.839 39.097 1.00 10.55 ? 395 PHE A CB 1 ATOM 2907 C CG . PHE A 1 362 ? -10.760 17.707 38.029 1.00 10.30 ? 395 PHE A CG 1 ATOM 2908 C CD1 . PHE A 1 362 ? -12.012 18.257 38.156 1.00 9.72 ? 395 PHE A CD1 1 ATOM 2909 C CD2 . PHE A 1 362 ? -10.054 17.938 36.839 1.00 10.06 ? 395 PHE A CD2 1 ATOM 2910 C CE1 . PHE A 1 362 ? -12.539 19.026 37.141 1.00 9.37 ? 395 PHE A CE1 1 ATOM 2911 C CE2 . PHE A 1 362 ? -10.600 18.687 35.817 1.00 9.65 ? 395 PHE A CE2 1 ATOM 2912 C CZ . PHE A 1 362 ? -11.838 19.245 35.984 1.00 9.41 ? 395 PHE A CZ 1 ATOM 2913 N N . THR A 1 363 ? -9.109 16.156 42.059 1.00 11.92 ? 396 THR A N 1 ATOM 2914 C CA . THR A 1 363 ? -8.474 15.190 42.965 1.00 12.01 ? 396 THR A CA 1 ATOM 2915 C C . THR A 1 363 ? -9.264 14.930 44.253 1.00 12.83 ? 396 THR A C 1 ATOM 2916 O O . THR A 1 363 ? -8.844 14.146 45.066 1.00 14.21 ? 396 THR A O 1 ATOM 2917 C CB . THR A 1 363 ? -7.094 15.622 43.426 1.00 12.26 ? 396 THR A CB 1 ATOM 2918 O OG1 . THR A 1 363 ? -7.204 16.676 44.387 1.00 12.22 ? 396 THR A OG1 1 ATOM 2919 C CG2 . THR A 1 363 ? -6.252 16.043 42.279 1.00 12.62 ? 396 THR A CG2 1 ATOM 2920 N N . ILE A 1 364 ? -10.398 15.586 44.461 1.00 13.14 ? 397 ILE A N 1 ATOM 2921 C CA . ILE A 1 364 ? -11.241 15.258 45.576 1.00 13.37 ? 397 ILE A CA 1 ATOM 2922 C C . ILE A 1 364 ? -11.642 13.826 45.380 1.00 14.19 ? 397 ILE A C 1 ATOM 2923 O O . ILE A 1 364 ? -11.798 13.365 44.286 1.00 12.78 ? 397 ILE A O 1 ATOM 2924 C CB . ILE A 1 364 ? -12.464 16.181 45.613 1.00 13.60 ? 397 ILE A CB 1 ATOM 2925 C CG1 . ILE A 1 364 ? -12.037 17.545 46.163 1.00 14.35 ? 397 ILE A CG1 1 ATOM 2926 C CG2 . ILE A 1 364 ? -13.613 15.585 46.407 1.00 13.45 ? 397 ILE A CG2 1 ATOM 2927 C CD1 . ILE A 1 364 ? -13.110 18.621 46.123 1.00 14.22 ? 397 ILE A CD1 1 ATOM 2928 N N . LEU A 1 365 ? -11.823 13.119 46.469 1.00 17.11 ? 398 LEU A N 1 ATOM 2929 C CA . LEU A 1 365 ? -12.219 11.726 46.401 1.00 19.05 ? 398 LEU A CA 1 ATOM 2930 C C . LEU A 1 365 ? -13.658 11.712 45.956 1.00 19.21 ? 398 LEU A C 1 ATOM 2931 O O . LEU A 1 365 ? -14.525 12.378 46.564 1.00 18.56 ? 398 LEU A O 1 ATOM 2932 C CB . LEU A 1 365 ? -12.094 11.107 47.772 1.00 22.37 ? 398 LEU A CB 1 ATOM 2933 C CG . LEU A 1 365 ? -12.401 9.623 47.941 1.00 24.23 ? 398 LEU A CG 1 ATOM 2934 C CD1 . LEU A 1 365 ? -11.317 8.807 47.241 1.00 25.86 ? 398 LEU A CD1 1 ATOM 2935 C CD2 . LEU A 1 365 ? -12.407 9.342 49.435 1.00 24.96 ? 398 LEU A CD2 1 ATOM 2936 N N . ASP A 1 366 ? -13.907 10.976 44.881 1.00 18.80 ? 399 ASP A N 1 ATOM 2937 C CA . ASP A 1 366 ? -15.217 10.925 44.235 1.00 18.85 ? 399 ASP A CA 1 ATOM 2938 C C . ASP A 1 366 ? -15.716 12.323 43.760 1.00 17.14 ? 399 ASP A C 1 ATOM 2939 O O . ASP A 1 366 ? -16.907 12.620 43.737 1.00 16.09 ? 399 ASP A O 1 ATOM 2940 C CB . ASP A 1 366 ? -16.230 10.200 45.125 1.00 21.75 ? 399 ASP A CB 1 ATOM 2941 C CG . ASP A 1 366 ? -15.884 8.687 45.337 1.00 28.42 ? 399 ASP A CG 1 ATOM 2942 O OD1 . ASP A 1 366 ? -15.030 8.076 44.607 1.00 30.48 ? 399 ASP A OD1 1 ATOM 2943 O OD2 . ASP A 1 366 ? -16.461 8.084 46.291 1.00 35.06 -1 399 ASP A OD2 1 ATOM 2944 N N . SER A 1 367 ? -14.784 13.170 43.353 1.00 15.80 ? 400 SER A N 1 ATOM 2945 C CA . SER A 1 367 ? -15.111 14.466 42.789 1.00 14.65 ? 400 SER A CA 1 ATOM 2946 C C . SER A 1 367 ? -16.189 14.435 41.698 1.00 15.41 ? 400 SER A C 1 ATOM 2947 O O . SER A 1 367 ? -16.041 13.782 40.667 1.00 16.95 ? 400 SER A O 1 ATOM 2948 C CB . SER A 1 367 ? -13.870 15.034 42.163 1.00 13.99 ? 400 SER A CB 1 ATOM 2949 O OG . SER A 1 367 ? -14.245 16.224 41.570 1.00 15.60 ? 400 SER A OG 1 ATOM 2950 N N . LYS A 1 368 ? -17.286 15.112 41.935 1.00 16.22 ? 401 LYS A N 1 ATOM 2951 C CA . LYS A 1 368 ? -18.270 15.406 40.900 1.00 18.30 ? 401 LYS A CA 1 ATOM 2952 C C . LYS A 1 368 ? -17.758 16.288 39.743 1.00 16.38 ? 401 LYS A C 1 ATOM 2953 O O . LYS A 1 368 ? -18.201 16.144 38.619 1.00 13.88 ? 401 LYS A O 1 ATOM 2954 C CB . LYS A 1 368 ? -19.528 16.027 41.535 1.00 20.25 ? 401 LYS A CB 1 ATOM 2955 C CG . LYS A 1 368 ? -20.526 14.973 42.013 1.00 24.83 ? 401 LYS A CG 1 ATOM 2956 C CD . LYS A 1 368 ? -19.914 13.575 42.314 1.00 28.44 ? 401 LYS A CD 1 ATOM 2957 C CE . LYS A 1 368 ? -20.958 12.509 42.687 1.00 31.09 ? 401 LYS A CE 1 ATOM 2958 N NZ . LYS A 1 368 ? -20.348 11.224 43.149 1.00 31.97 1 401 LYS A NZ 1 ATOM 2959 N N . GLN A 1 369 ? -16.841 17.192 40.052 1.00 15.91 ? 402 GLN A N 1 ATOM 2960 C CA . GLN A 1 369 ? -16.213 18.033 39.046 1.00 16.93 ? 402 GLN A CA 1 ATOM 2961 C C . GLN A 1 369 ? -15.493 17.136 38.028 1.00 15.32 ? 402 GLN A C 1 ATOM 2962 O O . GLN A 1 369 ? -15.630 17.352 36.826 1.00 14.76 ? 402 GLN A O 1 ATOM 2963 C CB . GLN A 1 369 ? -15.193 19.023 39.664 1.00 18.93 ? 402 GLN A CB 1 ATOM 2964 C CG . GLN A 1 369 ? -15.740 20.052 40.661 1.00 21.46 ? 402 GLN A CG 1 ATOM 2965 C CD . GLN A 1 369 ? -16.497 21.133 39.950 1.00 25.28 ? 402 GLN A CD 1 ATOM 2966 O OE1 . GLN A 1 369 ? -17.457 20.830 39.214 1.00 28.95 ? 402 GLN A OE1 1 ATOM 2967 N NE2 . GLN A 1 369 ? -16.058 22.415 40.114 1.00 25.88 ? 402 GLN A NE2 1 ATOM 2968 N N . PHE A 1 370 ? -14.733 16.145 38.512 1.00 13.05 ? 403 PHE A N 1 ATOM 2969 C CA . PHE A 1 370 ? -13.943 15.325 37.637 1.00 12.09 ? 403 PHE A CA 1 ATOM 2970 C C . PHE A 1 370 ? -14.816 14.478 36.745 1.00 12.42 ? 403 PHE A C 1 ATOM 2971 O O . PHE A 1 370 ? -14.474 14.258 35.591 1.00 11.02 ? 403 PHE A O 1 ATOM 2972 C CB . PHE A 1 370 ? -13.024 14.368 38.372 1.00 11.15 ? 403 PHE A CB 1 ATOM 2973 C CG . PHE A 1 370 ? -12.320 13.454 37.443 1.00 9.90 ? 403 PHE A CG 1 ATOM 2974 C CD1 . PHE A 1 370 ? -11.368 13.958 36.575 1.00 9.67 ? 403 PHE A CD1 1 ATOM 2975 C CD2 . PHE A 1 370 ? -12.700 12.149 37.317 1.00 9.56 ? 403 PHE A CD2 1 ATOM 2976 C CE1 . PHE A 1 370 ? -10.746 13.129 35.672 1.00 9.38 ? 403 PHE A CE1 1 ATOM 2977 C CE2 . PHE A 1 370 ? -12.104 11.299 36.396 1.00 9.26 ? 403 PHE A CE2 1 ATOM 2978 C CZ . PHE A 1 370 ? -11.117 11.797 35.574 1.00 9.22 ? 403 PHE A CZ 1 ATOM 2979 N N . ILE A 1 371 ? -15.917 14.005 37.316 1.00 13.24 ? 404 ILE A N 1 ATOM 2980 C CA . ILE A 1 371 ? -16.925 13.245 36.608 1.00 14.80 ? 404 ILE A CA 1 ATOM 2981 C C . ILE A 1 371 ? -17.549 13.988 35.433 1.00 12.89 ? 404 ILE A C 1 ATOM 2982 O O . ILE A 1 371 ? -17.690 13.436 34.361 1.00 11.72 ? 404 ILE A O 1 ATOM 2983 C CB . ILE A 1 371 ? -18.009 12.784 37.590 1.00 18.23 ? 404 ILE A CB 1 ATOM 2984 C CG1 . ILE A 1 371 ? -17.415 11.681 38.485 1.00 22.32 ? 404 ILE A CG1 1 ATOM 2985 C CG2 . ILE A 1 371 ? -19.195 12.130 36.869 1.00 19.29 ? 404 ILE A CG2 1 ATOM 2986 C CD1 . ILE A 1 371 ? -17.217 10.343 37.726 1.00 25.30 ? 404 ILE A CD1 1 ATOM 2987 N N . LYS A 1 372 ? -17.939 15.222 35.671 1.00 11.74 ? 405 LYS A N 1 ATOM 2988 C CA . LYS A 1 372 ? -18.341 16.127 34.627 1.00 11.60 ? 405 LYS A CA 1 ATOM 2989 C C . LYS A 1 372 ? -17.266 16.232 33.553 1.00 10.25 ? 405 LYS A C 1 ATOM 2990 O O . LYS A 1 372 ? -17.561 16.094 32.376 1.00 9.48 ? 405 LYS A O 1 ATOM 2991 C CB . LYS A 1 372 ? -18.458 17.519 35.182 1.00 13.10 ? 405 LYS A CB 1 ATOM 2992 C CG . LYS A 1 372 ? -19.828 17.961 35.450 1.00 15.33 ? 405 LYS A CG 1 ATOM 2993 C CD . LYS A 1 372 ? -19.873 19.487 35.518 1.00 16.68 ? 405 LYS A CD 1 ATOM 2994 C CE . LYS A 1 372 ? -21.269 19.893 35.951 1.00 17.37 ? 405 LYS A CE 1 ATOM 2995 N NZ . LYS A 1 372 ? -21.223 21.274 36.496 1.00 18.60 1 405 LYS A NZ 1 ATOM 2996 N N . TYR A 1 373 ? -16.048 16.518 34.004 1.00 8.74 ? 406 TYR A N 1 ATOM 2997 C CA . TYR A 1 373 ? -14.923 16.673 33.153 1.00 8.69 ? 406 TYR A CA 1 ATOM 2998 C C . TYR A 1 373 ? -14.768 15.467 32.212 1.00 8.49 ? 406 TYR A C 1 ATOM 2999 O O . TYR A 1 373 ? -14.466 15.643 31.023 1.00 8.24 ? 406 TYR A O 1 ATOM 3000 C CB . TYR A 1 373 ? -13.642 16.818 33.985 1.00 8.67 ? 406 TYR A CB 1 ATOM 3001 C CG . TYR A 1 373 ? -12.412 16.923 33.145 1.00 8.69 ? 406 TYR A CG 1 ATOM 3002 C CD1 . TYR A 1 373 ? -12.112 18.098 32.527 1.00 9.26 ? 406 TYR A CD1 1 ATOM 3003 C CD2 . TYR A 1 373 ? -11.589 15.868 32.939 1.00 8.85 ? 406 TYR A CD2 1 ATOM 3004 C CE1 . TYR A 1 373 ? -11.004 18.249 31.739 1.00 9.58 ? 406 TYR A CE1 1 ATOM 3005 C CE2 . TYR A 1 373 ? -10.466 15.998 32.142 1.00 9.41 ? 406 TYR A CE2 1 ATOM 3006 C CZ . TYR A 1 373 ? -10.182 17.210 31.552 1.00 9.91 ? 406 TYR A CZ 1 ATOM 3007 O OH . TYR A 1 373 ? -9.069 17.432 30.743 1.00 11.43 ? 406 TYR A OH 1 ATOM 3008 N N . TYR A 1 374 ? -15.007 14.281 32.764 1.00 8.01 ? 407 TYR A N 1 ATOM 3009 C CA . TYR A 1 374 ? -14.863 13.056 32.057 1.00 8.18 ? 407 TYR A CA 1 ATOM 3010 C C . TYR A 1 374 ? -15.964 12.872 30.984 1.00 8.16 ? 407 TYR A C 1 ATOM 3011 O O . TYR A 1 374 ? -15.702 12.403 29.898 1.00 8.33 ? 407 TYR A O 1 ATOM 3012 C CB . TYR A 1 374 ? -14.847 11.851 33.031 1.00 8.10 ? 407 TYR A CB 1 ATOM 3013 C CG . TYR A 1 374 ? -14.146 10.664 32.433 1.00 8.10 ? 407 TYR A CG 1 ATOM 3014 C CD1 . TYR A 1 374 ? -12.813 10.737 32.053 1.00 8.36 ? 407 TYR A CD1 1 ATOM 3015 C CD2 . TYR A 1 374 ? -14.806 9.485 32.203 1.00 8.17 ? 407 TYR A CD2 1 ATOM 3016 C CE1 . TYR A 1 374 ? -12.172 9.651 31.495 1.00 8.07 ? 407 TYR A CE1 1 ATOM 3017 C CE2 . TYR A 1 374 ? -14.167 8.393 31.635 1.00 7.99 ? 407 TYR A CE2 1 ATOM 3018 C CZ . TYR A 1 374 ? -12.873 8.505 31.306 1.00 8.07 ? 407 TYR A CZ 1 ATOM 3019 O OH . TYR A 1 374 ? -12.294 7.450 30.740 1.00 8.73 ? 407 TYR A OH 1 ATOM 3020 N N . ASN A 1 375 ? -17.163 13.283 31.267 1.00 8.16 ? 408 ASN A N 1 ATOM 3021 C CA . ASN A 1 375 ? -18.155 13.263 30.276 1.00 8.86 ? 408 ASN A CA 1 ATOM 3022 C C . ASN A 1 375 ? -17.875 14.234 29.116 1.00 7.94 ? 408 ASN A C 1 ATOM 3023 O O . ASN A 1 375 ? -18.029 13.900 27.965 1.00 7.42 ? 408 ASN A O 1 ATOM 3024 C CB . ASN A 1 375 ? -19.497 13.623 30.899 1.00 10.81 ? 408 ASN A CB 1 ATOM 3025 C CG . ASN A 1 375 ? -20.058 12.507 31.757 1.00 13.11 ? 408 ASN A CG 1 ATOM 3026 O OD1 . ASN A 1 375 ? -19.762 11.303 31.603 1.00 15.14 ? 408 ASN A OD1 1 ATOM 3027 N ND2 . ASN A 1 375 ? -20.862 12.915 32.719 1.00 16.36 ? 408 ASN A ND2 1 ATOM 3028 N N . TYR A 1 376 ? -17.511 15.459 29.455 1.00 7.07 ? 409 TYR A N 1 ATOM 3029 C CA . TYR A 1 376 ? -17.167 16.426 28.485 1.00 6.44 ? 409 TYR A CA 1 ATOM 3030 C C . TYR A 1 376 ? -15.923 15.998 27.702 1.00 5.80 ? 409 TYR A C 1 ATOM 3031 O O . TYR A 1 376 ? -15.735 16.432 26.587 1.00 5.50 ? 409 TYR A O 1 ATOM 3032 C CB . TYR A 1 376 ? -16.875 17.751 29.194 1.00 6.63 ? 409 TYR A CB 1 ATOM 3033 C CG . TYR A 1 376 ? -18.038 18.431 29.821 1.00 6.82 ? 409 TYR A CG 1 ATOM 3034 C CD1 . TYR A 1 376 ? -19.345 18.190 29.397 1.00 7.29 ? 409 TYR A CD1 1 ATOM 3035 C CD2 . TYR A 1 376 ? -17.845 19.321 30.846 1.00 7.00 ? 409 TYR A CD2 1 ATOM 3036 C CE1 . TYR A 1 376 ? -20.436 18.829 29.996 1.00 7.34 ? 409 TYR A CE1 1 ATOM 3037 C CE2 . TYR A 1 376 ? -18.907 19.965 31.442 1.00 7.44 ? 409 TYR A CE2 1 ATOM 3038 C CZ . TYR A 1 376 ? -20.207 19.706 31.008 1.00 7.80 ? 409 TYR A CZ 1 ATOM 3039 O OH . TYR A 1 376 ? -21.275 20.365 31.587 1.00 8.75 ? 409 TYR A OH 1 ATOM 3040 N N . PHE A 1 377 ? -15.038 15.217 28.315 1.00 5.16 ? 410 PHE A N 1 ATOM 3041 C CA . PHE A 1 377 ? -13.846 14.776 27.622 1.00 4.79 ? 410 PHE A CA 1 ATOM 3042 C C . PHE A 1 377 ? -14.201 14.115 26.286 1.00 4.84 ? 410 PHE A C 1 ATOM 3043 O O . PHE A 1 377 ? -13.550 14.326 25.277 1.00 4.69 ? 410 PHE A O 1 ATOM 3044 C CB . PHE A 1 377 ? -13.089 13.827 28.516 1.00 4.43 ? 410 PHE A CB 1 ATOM 3045 C CG . PHE A 1 377 ? -11.845 13.265 27.927 1.00 4.06 ? 410 PHE A CG 1 ATOM 3046 C CD1 . PHE A 1 377 ? -10.742 14.026 27.768 1.00 3.92 ? 410 PHE A CD1 1 ATOM 3047 C CD2 . PHE A 1 377 ? -11.768 11.925 27.609 1.00 4.09 ? 410 PHE A CD2 1 ATOM 3048 C CE1 . PHE A 1 377 ? -9.555 13.477 27.300 1.00 3.89 ? 410 PHE A CE1 1 ATOM 3049 C CE2 . PHE A 1 377 ? -10.581 11.352 27.132 1.00 4.01 ? 410 PHE A CE2 1 ATOM 3050 C CZ . PHE A 1 377 ? -9.472 12.147 26.959 1.00 3.91 ? 410 PHE A CZ 1 ATOM 3051 N N . PHE A 1 378 ? -15.260 13.328 26.307 1.00 5.08 ? 411 PHE A N 1 ATOM 3052 C CA . PHE A 1 378 ? -15.796 12.686 25.115 1.00 5.26 ? 411 PHE A CA 1 ATOM 3053 C C . PHE A 1 378 ? -16.905 13.482 24.440 1.00 5.34 ? 411 PHE A C 1 ATOM 3054 O O . PHE A 1 378 ? -17.698 12.903 23.777 1.00 5.63 ? 411 PHE A O 1 ATOM 3055 C CB . PHE A 1 378 ? -16.364 11.316 25.485 1.00 5.22 ? 411 PHE A CB 1 ATOM 3056 C CG . PHE A 1 378 ? -15.341 10.394 26.086 1.00 5.45 ? 411 PHE A CG 1 ATOM 3057 C CD1 . PHE A 1 378 ? -14.325 9.826 25.279 1.00 5.46 ? 411 PHE A CD1 1 ATOM 3058 C CD2 . PHE A 1 378 ? -15.366 10.066 27.469 1.00 5.34 ? 411 PHE A CD2 1 ATOM 3059 C CE1 . PHE A 1 378 ? -13.365 8.976 25.850 1.00 5.50 ? 411 PHE A CE1 1 ATOM 3060 C CE2 . PHE A 1 378 ? -14.401 9.213 28.015 1.00 5.36 ? 411 PHE A CE2 1 ATOM 3061 C CZ . PHE A 1 378 ? -13.388 8.680 27.230 1.00 5.28 ? 411 PHE A CZ 1 ATOM 3062 N N . VAL A 1 379 ? -17.004 14.776 24.683 1.00 5.38 ? 412 VAL A N 1 ATOM 3063 C CA . VAL A 1 379 ? -18.091 15.611 24.195 1.00 5.43 ? 412 VAL A CA 1 ATOM 3064 C C . VAL A 1 379 ? -19.472 15.004 24.393 1.00 5.96 ? 412 VAL A C 1 ATOM 3065 O O . VAL A 1 379 ? -20.355 15.025 23.485 1.00 6.28 ? 412 VAL A O 1 ATOM 3066 C CB . VAL A 1 379 ? -17.872 16.029 22.738 1.00 5.12 ? 412 VAL A CB 1 ATOM 3067 C CG1 . VAL A 1 379 ? -18.639 17.267 22.450 1.00 4.96 ? 412 VAL A CG1 1 ATOM 3068 C CG2 . VAL A 1 379 ? -16.432 16.406 22.485 1.00 5.26 ? 412 VAL A CG2 1 ATOM 3069 N N . SER A 1 380 ? -19.639 14.371 25.529 1.00 6.49 ? 413 SER A N 1 ATOM 3070 C CA . SER A 1 380 ? -20.865 13.701 25.954 1.00 7.21 ? 413 SER A CA 1 ATOM 3071 C C . SER A 1 380 ? -21.371 12.519 25.156 1.00 8.44 ? 413 SER A C 1 ATOM 3072 O O . SER A 1 380 ? -22.527 12.248 25.201 1.00 8.47 ? 413 SER A O 1 ATOM 3073 C CB . SER A 1 380 ? -21.981 14.709 26.165 1.00 7.01 ? 413 SER A CB 1 ATOM 3074 O OG . SER A 1 380 ? -21.570 15.800 26.916 1.00 6.97 ? 413 SER A OG 1 ATOM 3075 N N . TYR A 1 381 ? -20.494 11.824 24.460 1.00 10.53 ? 414 TYR A N 1 ATOM 3076 C CA . TYR A 1 381 ? -20.869 10.676 23.696 1.00 12.77 ? 414 TYR A CA 1 ATOM 3077 C C . TYR A 1 381 ? -21.655 9.631 24.501 1.00 16.72 ? 414 TYR A C 1 ATOM 3078 O O . TYR A 1 381 ? -22.649 9.160 24.023 1.00 20.15 ? 414 TYR A O 1 ATOM 3079 C CB . TYR A 1 381 ? -19.683 10.151 22.945 1.00 11.57 ? 414 TYR A CB 1 ATOM 3080 C CG . TYR A 1 381 ? -19.993 8.971 22.151 1.00 10.70 ? 414 TYR A CG 1 ATOM 3081 C CD1 . TYR A 1 381 ? -20.729 9.059 21.000 1.00 11.03 ? 414 TYR A CD1 1 ATOM 3082 C CD2 . TYR A 1 381 ? -19.577 7.774 22.563 1.00 10.41 ? 414 TYR A CD2 1 ATOM 3083 C CE1 . TYR A 1 381 ? -20.993 7.954 20.278 1.00 11.33 ? 414 TYR A CE1 1 ATOM 3084 C CE2 . TYR A 1 381 ? -19.861 6.658 21.889 1.00 10.55 ? 414 TYR A CE2 1 ATOM 3085 C CZ . TYR A 1 381 ? -20.540 6.743 20.745 1.00 11.41 ? 414 TYR A CZ 1 ATOM 3086 O OH . TYR A 1 381 ? -20.776 5.613 20.067 1.00 11.76 ? 414 TYR A OH 1 ATOM 3087 N N . ASP A 1 382 ? -21.282 9.309 25.715 1.00 23.04 ? 415 ASP A N 1 ATOM 3088 C CA . ASP A 1 382 ? -22.217 8.578 26.582 1.00 30.61 ? 415 ASP A CA 1 ATOM 3089 C C . ASP A 1 382 ? -22.294 9.183 27.995 1.00 34.61 ? 415 ASP A C 1 ATOM 3090 O O . ASP A 1 382 ? -21.332 9.117 28.704 1.00 43.98 ? 415 ASP A O 1 ATOM 3091 C CB . ASP A 1 382 ? -21.851 7.100 26.672 1.00 38.13 ? 415 ASP A CB 1 ATOM 3092 C CG . ASP A 1 382 ? -22.804 6.177 25.882 1.00 45.35 ? 415 ASP A CG 1 ATOM 3093 O OD1 . ASP A 1 382 ? -23.933 6.591 25.553 1.00 46.23 ? 415 ASP A OD1 1 ATOM 3094 O OD2 . ASP A 1 382 ? -22.424 5.006 25.610 1.00 40.47 -1 415 ASP A OD2 1 ATOM 3095 N N . SER A 1 383 ? -23.393 9.806 28.402 1.00 38.73 ? 416 SER A N 1 ATOM 3096 C CA . SER A 1 383 ? -23.686 10.061 29.835 1.00 39.03 ? 416 SER A CA 1 ATOM 3097 C C . SER A 1 383 ? -23.154 9.032 30.837 1.00 39.56 ? 416 SER A C 1 ATOM 3098 O O . SER A 1 383 ? -22.340 9.318 31.682 1.00 42.90 ? 416 SER A O 1 ATOM 3099 C CB . SER A 1 383 ? -25.201 10.000 29.992 1.00 39.03 ? 416 SER A CB 1 ATOM 3100 O OG . SER A 1 383 ? -25.762 9.233 28.920 1.00 35.67 ? 416 SER A OG 1 ATOM 3101 N N . SER A 1 384 ? -23.570 7.794 30.668 1.00 42.54 ? 417 SER A N 1 ATOM 3102 C CA . SER A 1 384 ? -23.294 6.742 31.621 1.00 40.02 ? 417 SER A CA 1 ATOM 3103 C C . SER A 1 384 ? -21.810 6.433 31.656 1.00 37.16 ? 417 SER A C 1 ATOM 3104 O O . SER A 1 384 ? -21.386 5.458 32.286 1.00 42.24 ? 417 SER A O 1 ATOM 3105 C CB . SER A 1 384 ? -24.084 5.466 31.247 1.00 41.23 ? 417 SER A CB 1 ATOM 3106 O OG . SER A 1 384 ? -23.507 4.810 30.117 1.00 46.11 ? 417 SER A OG 1 ATOM 3107 N N . VAL A 1 385 ? -20.983 7.214 30.988 1.00 35.19 ? 418 VAL A N 1 ATOM 3108 C CA . VAL A 1 385 ? -19.584 6.820 30.952 1.00 33.13 ? 418 VAL A CA 1 ATOM 3109 C C . VAL A 1 385 ? -19.024 7.069 32.328 1.00 28.05 ? 418 VAL A C 1 ATOM 3110 O O . VAL A 1 385 ? -19.148 8.172 32.886 1.00 28.16 ? 418 VAL A O 1 ATOM 3111 C CB . VAL A 1 385 ? -18.751 7.503 29.842 1.00 35.26 ? 418 VAL A CB 1 ATOM 3112 C CG1 . VAL A 1 385 ? -18.241 8.889 30.264 1.00 32.84 ? 418 VAL A CG1 1 ATOM 3113 C CG2 . VAL A 1 385 ? -17.577 6.581 29.475 1.00 39.06 ? 418 VAL A CG2 1 ATOM 3114 N N . THR A 1 386 ? -18.476 6.003 32.875 1.00 23.21 ? 419 THR A N 1 ATOM 3115 C CA . THR A 1 386 ? -17.896 5.992 34.211 1.00 20.45 ? 419 THR A CA 1 ATOM 3116 C C . THR A 1 386 ? -16.391 5.969 34.006 1.00 18.07 ? 419 THR A C 1 ATOM 3117 O O . THR A 1 386 ? -15.936 5.892 32.910 1.00 20.38 ? 419 THR A O 1 ATOM 3118 C CB . THR A 1 386 ? -18.397 4.765 35.005 1.00 18.82 ? 419 THR A CB 1 ATOM 3119 O OG1 . THR A 1 386 ? -17.702 4.651 36.232 1.00 18.40 ? 419 THR A OG1 1 ATOM 3120 C CG2 . THR A 1 386 ? -18.176 3.510 34.244 1.00 18.32 ? 419 THR A CG2 1 ATOM 3121 N N . CYS A 1 387 ? -15.632 6.027 35.064 1.00 16.79 ? 420 CYS A N 1 ATOM 3122 C CA . CYS A 1 387 ? -14.163 6.076 34.996 1.00 15.73 ? 420 CYS A CA 1 ATOM 3123 C C . CYS A 1 387 ? -13.623 5.355 36.225 1.00 15.38 ? 420 CYS A C 1 ATOM 3124 O O . CYS A 1 387 ? -14.207 5.459 37.283 1.00 15.01 ? 420 CYS A O 1 ATOM 3125 C CB . CYS A 1 387 ? -13.735 7.520 35.042 1.00 14.70 ? 420 CYS A CB 1 ATOM 3126 S SG . CYS A 1 387 ? -12.007 7.741 34.779 1.00 15.00 ? 420 CYS A SG 1 ATOM 3127 N N . ASP A 1 388 ? -12.584 4.571 36.074 1.00 15.08 ? 421 ASP A N 1 ATOM 3128 C CA . ASP A 1 388 ? -11.988 3.895 37.207 1.00 15.99 ? 421 ASP A CA 1 ATOM 3129 C C . ASP A 1 388 ? -10.807 4.672 37.737 1.00 16.06 ? 421 ASP A C 1 ATOM 3130 O O . ASP A 1 388 ? -10.392 5.626 37.116 1.00 17.88 ? 421 ASP A O 1 ATOM 3131 C CB . ASP A 1 388 ? -11.589 2.492 36.805 1.00 16.81 ? 421 ASP A CB 1 ATOM 3132 C CG . ASP A 1 388 ? -10.313 2.436 36.020 1.00 18.07 ? 421 ASP A CG 1 ATOM 3133 O OD1 . ASP A 1 388 ? -9.842 3.412 35.375 1.00 21.43 ? 421 ASP A OD1 1 ATOM 3134 O OD2 . ASP A 1 388 ? -9.757 1.353 36.039 1.00 19.10 -1 421 ASP A OD2 1 ATOM 3135 N N . LYS A 1 389 ? -10.292 4.286 38.891 1.00 16.89 ? 422 LYS A N 1 ATOM 3136 C CA . LYS A 1 389 ? -9.187 4.984 39.545 1.00 18.16 ? 422 LYS A CA 1 ATOM 3137 C C . LYS A 1 389 ? -7.905 5.159 38.760 1.00 16.85 ? 422 LYS A C 1 ATOM 3138 O O . LYS A 1 389 ? -7.249 6.153 38.850 1.00 19.10 ? 422 LYS A O 1 ATOM 3139 C CB . LYS A 1 389 ? -8.753 4.202 40.745 1.00 22.05 ? 422 LYS A CB 1 ATOM 3140 C CG . LYS A 1 389 ? -9.687 4.263 41.915 1.00 27.22 ? 422 LYS A CG 1 ATOM 3141 C CD . LYS A 1 389 ? -9.121 3.398 43.069 1.00 33.03 ? 422 LYS A CD 1 ATOM 3142 C CE . LYS A 1 389 ? -8.595 2.022 42.627 1.00 33.94 ? 422 LYS A CE 1 ATOM 3143 N NZ . LYS A 1 389 ? -8.934 0.959 43.627 1.00 38.97 1 422 LYS A NZ 1 ATOM 3144 N N . THR A 1 390 ? -7.484 4.148 38.066 1.00 15.32 ? 423 THR A N 1 ATOM 3145 C CA . THR A 1 390 ? -6.336 4.236 37.240 1.00 15.07 ? 423 THR A CA 1 ATOM 3146 C C . THR A 1 390 ? -6.492 5.299 36.121 1.00 15.07 ? 423 THR A C 1 ATOM 3147 O O . THR A 1 390 ? -5.605 6.120 35.896 1.00 14.09 ? 423 THR A O 1 ATOM 3148 C CB . THR A 1 390 ? -6.150 2.825 36.689 1.00 16.54 ? 423 THR A CB 1 ATOM 3149 O OG1 . THR A 1 390 ? -6.102 1.958 37.811 1.00 18.05 ? 423 THR A OG1 1 ATOM 3150 C CG2 . THR A 1 390 ? -4.875 2.625 35.914 1.00 16.82 ? 423 THR A CG2 1 ATOM 3151 N N . CYS A 1 391 ? -7.605 5.271 35.400 1.00 15.81 ? 424 CYS A N 1 ATOM 3152 C CA . CYS A 1 391 ? -7.826 6.269 34.373 1.00 16.96 ? 424 CYS A CA 1 ATOM 3153 C C . CYS A 1 391 ? -7.816 7.673 34.969 1.00 14.94 ? 424 CYS A C 1 ATOM 3154 O O . CYS A 1 391 ? -7.275 8.609 34.380 1.00 13.51 ? 424 CYS A O 1 ATOM 3155 C CB . CYS A 1 391 ? -9.137 6.023 33.609 1.00 19.31 ? 424 CYS A CB 1 ATOM 3156 S SG . CYS A 1 391 ? -9.001 4.615 32.456 1.00 27.13 ? 424 CYS A SG 1 ATOM 3157 N N . LYS A 1 392 ? -8.435 7.811 36.134 1.00 13.29 ? 425 LYS A N 1 ATOM 3158 C CA . LYS A 1 392 ? -8.535 9.111 36.747 1.00 12.41 ? 425 LYS A CA 1 ATOM 3159 C C . LYS A 1 392 ? -7.158 9.590 37.087 1.00 12.13 ? 425 LYS A C 1 ATOM 3160 O O . LYS A 1 392 ? -6.810 10.697 36.847 1.00 11.97 ? 425 LYS A O 1 ATOM 3161 C CB . LYS A 1 392 ? -9.348 9.042 38.000 1.00 11.51 ? 425 LYS A CB 1 ATOM 3162 C CG . LYS A 1 392 ? -9.287 10.354 38.744 1.00 10.78 ? 425 LYS A CG 1 ATOM 3163 C CD . LYS A 1 392 ? -10.408 10.422 39.747 1.00 9.94 ? 425 LYS A CD 1 ATOM 3164 C CE . LYS A 1 392 ? -10.236 11.684 40.557 1.00 9.77 ? 425 LYS A CE 1 ATOM 3165 N NZ . LYS A 1 392 ? -11.309 11.829 41.550 1.00 9.50 1 425 LYS A NZ 1 ATOM 3166 N N . ALA A 1 393 ? -6.351 8.710 37.612 1.00 12.26 ? 426 ALA A N 1 ATOM 3167 C CA . ALA A 1 393 ? -5.008 9.086 37.902 1.00 12.86 ? 426 ALA A CA 1 ATOM 3168 C C . ALA A 1 393 ? -4.272 9.536 36.617 1.00 12.53 ? 426 ALA A C 1 ATOM 3169 O O . ALA A 1 393 ? -3.580 10.564 36.625 1.00 11.55 ? 426 ALA A O 1 ATOM 3170 C CB . ALA A 1 393 ? -4.295 7.940 38.623 1.00 12.96 ? 426 ALA A CB 1 ATOM 3171 N N . PHE A 1 394 ? -4.440 8.805 35.529 1.00 12.91 ? 427 PHE A N 1 ATOM 3172 C CA . PHE A 1 394 ? -3.853 9.255 34.245 1.00 14.23 ? 427 PHE A CA 1 ATOM 3173 C C . PHE A 1 394 ? -4.379 10.644 33.818 1.00 13.64 ? 427 PHE A C 1 ATOM 3174 O O . PHE A 1 394 ? -3.624 11.453 33.331 1.00 13.58 ? 427 PHE A O 1 ATOM 3175 C CB . PHE A 1 394 ? -4.141 8.272 33.072 1.00 15.48 ? 427 PHE A CB 1 ATOM 3176 C CG . PHE A 1 394 ? -3.610 6.870 33.272 1.00 17.29 ? 427 PHE A CG 1 ATOM 3177 C CD1 . PHE A 1 394 ? -2.551 6.606 34.144 1.00 17.78 ? 427 PHE A CD1 1 ATOM 3178 C CD2 . PHE A 1 394 ? -4.164 5.813 32.551 1.00 18.25 ? 427 PHE A CD2 1 ATOM 3179 C CE1 . PHE A 1 394 ? -2.097 5.315 34.332 1.00 18.91 ? 427 PHE A CE1 1 ATOM 3180 C CE2 . PHE A 1 394 ? -3.703 4.534 32.712 1.00 19.16 ? 427 PHE A CE2 1 ATOM 3181 C CZ . PHE A 1 394 ? -2.657 4.278 33.607 1.00 19.96 ? 427 PHE A CZ 1 ATOM 3182 N N . GLN A 1 395 ? -5.664 10.910 33.995 1.00 12.52 ? 428 GLN A N 1 ATOM 3183 C CA . GLN A 1 395 ? -6.217 12.173 33.615 1.00 13.22 ? 428 GLN A CA 1 ATOM 3184 C C . GLN A 1 395 ? -5.662 13.309 34.481 1.00 14.27 ? 428 GLN A C 1 ATOM 3185 O O . GLN A 1 395 ? -5.100 14.289 33.971 1.00 13.21 ? 428 GLN A O 1 ATOM 3186 C CB . GLN A 1 395 ? -7.726 12.126 33.695 1.00 13.52 ? 428 GLN A CB 1 ATOM 3187 C CG . GLN A 1 395 ? -8.344 11.236 32.607 1.00 14.32 ? 428 GLN A CG 1 ATOM 3188 C CD . GLN A 1 395 ? -8.562 11.988 31.282 1.00 14.60 ? 428 GLN A CD 1 ATOM 3189 O OE1 . GLN A 1 395 ? -8.702 13.209 31.273 1.00 17.19 ? 428 GLN A OE1 1 ATOM 3190 N NE2 . GLN A 1 395 ? -8.652 11.280 30.205 1.00 13.32 ? 428 GLN A NE2 1 ATOM 3191 N N . ILE A 1 396 ? -5.786 13.147 35.793 1.00 14.87 ? 429 ILE A N 1 ATOM 3192 C CA . ILE A 1 396 ? -5.307 14.140 36.751 1.00 15.31 ? 429 ILE A CA 1 ATOM 3193 C C . ILE A 1 396 ? -3.855 14.509 36.524 1.00 14.72 ? 429 ILE A C 1 ATOM 3194 O O . ILE A 1 396 ? -3.510 15.681 36.426 1.00 14.55 ? 429 ILE A O 1 ATOM 3195 C CB . ILE A 1 396 ? -5.426 13.606 38.181 1.00 16.46 ? 429 ILE A CB 1 ATOM 3196 C CG1 . ILE A 1 396 ? -6.877 13.441 38.578 1.00 16.73 ? 429 ILE A CG1 1 ATOM 3197 C CG2 . ILE A 1 396 ? -4.791 14.538 39.186 1.00 18.07 ? 429 ILE A CG2 1 ATOM 3198 C CD1 . ILE A 1 396 ? -7.718 14.617 38.281 1.00 16.84 ? 429 ILE A CD1 1 ATOM 3199 N N . CYS A 1 397 ? -2.993 13.519 36.465 1.00 13.96 ? 430 CYS A N 1 ATOM 3200 C CA . CYS A 1 397 ? -1.618 13.825 36.314 1.00 14.13 ? 430 CYS A CA 1 ATOM 3201 C C . CYS A 1 397 ? -1.312 14.525 35.019 1.00 13.21 ? 430 CYS A C 1 ATOM 3202 O O . CYS A 1 397 ? -0.482 15.412 34.990 1.00 13.56 ? 430 CYS A O 1 ATOM 3203 C CB . CYS A 1 397 ? -0.789 12.565 36.516 1.00 16.04 ? 430 CYS A CB 1 ATOM 3204 S SG . CYS A 1 397 ? -0.949 11.982 38.236 1.00 17.80 ? 430 CYS A SG 1 ATOM 3205 N N . ALA A 1 398 ? -2.013 14.175 33.953 1.00 12.65 ? 431 ALA A N 1 ATOM 3206 C CA . ALA A 1 398 ? -1.778 14.836 32.663 1.00 12.29 ? 431 ALA A CA 1 ATOM 3207 C C . ALA A 1 398 ? -2.245 16.274 32.631 1.00 11.21 ? 431 ALA A C 1 ATOM 3208 O O . ALA A 1 398 ? -1.680 17.083 31.944 1.00 11.71 ? 431 ALA A O 1 ATOM 3209 C CB . ALA A 1 398 ? -2.417 14.062 31.512 1.00 12.44 ? 431 ALA A CB 1 ATOM 3210 N N . ILE A 1 399 ? -3.288 16.586 33.341 1.00 11.26 ? 432 ILE A N 1 ATOM 3211 C CA . ILE A 1 399 ? -3.736 17.939 33.439 1.00 11.99 ? 432 ILE A CA 1 ATOM 3212 C C . ILE A 1 399 ? -2.685 18.810 34.114 1.00 13.37 ? 432 ILE A C 1 ATOM 3213 O O . ILE A 1 399 ? -2.393 19.894 33.662 1.00 13.00 ? 432 ILE A O 1 ATOM 3214 C CB . ILE A 1 399 ? -5.056 18.006 34.197 1.00 11.74 ? 432 ILE A CB 1 ATOM 3215 C CG1 . ILE A 1 399 ? -6.163 17.330 33.377 1.00 11.79 ? 432 ILE A CG1 1 ATOM 3216 C CG2 . ILE A 1 399 ? -5.442 19.444 34.419 1.00 11.93 ? 432 ILE A CG2 1 ATOM 3217 C CD1 . ILE A 1 399 ? -7.397 16.913 34.146 1.00 12.04 ? 432 ILE A CD1 1 ATOM 3218 N N . MET A 1 400 ? -2.081 18.313 35.183 1.00 15.90 ? 433 MET A N 1 ATOM 3219 C CA . MET A 1 400 ? -1.272 19.173 36.040 1.00 18.28 ? 433 MET A CA 1 ATOM 3220 C C . MET A 1 400 ? 0.215 19.026 35.816 1.00 18.22 ? 433 MET A C 1 ATOM 3221 O O . MET A 1 400 ? 0.941 19.840 36.326 1.00 18.92 ? 433 MET A O 1 ATOM 3222 C CB . MET A 1 400 ? -1.550 18.919 37.528 1.00 20.57 ? 433 MET A CB 1 ATOM 3223 C CG . MET A 1 400 ? -2.919 19.355 38.019 1.00 23.43 ? 433 MET A CG 1 ATOM 3224 S SD . MET A 1 400 ? -3.343 18.629 39.637 1.00 30.28 ? 433 MET A SD 1 ATOM 3225 C CE . MET A 1 400 ? -2.510 19.841 40.620 1.00 30.68 ? 433 MET A CE 1 ATOM 3226 N N . ASN A 1 401 ? 0.676 18.017 35.079 1.00 17.80 ? 434 ASN A N 1 ATOM 3227 C CA . ASN A 1 401 ? 2.102 17.752 34.987 1.00 18.15 ? 434 ASN A CA 1 ATOM 3228 C C . ASN A 1 401 ? 2.568 17.464 33.611 1.00 19.82 ? 434 ASN A C 1 ATOM 3229 O O . ASN A 1 401 ? 2.328 16.371 33.129 1.00 22.23 ? 434 ASN A O 1 ATOM 3230 C CB . ASN A 1 401 ? 2.427 16.538 35.831 1.00 18.25 ? 434 ASN A CB 1 ATOM 3231 C CG . ASN A 1 401 ? 2.122 16.771 37.280 1.00 17.72 ? 434 ASN A CG 1 ATOM 3232 O OD1 . ASN A 1 401 ? 2.823 17.546 37.951 1.00 19.22 ? 434 ASN A OD1 1 ATOM 3233 N ND2 . ASN A 1 401 ? 1.041 16.180 37.754 1.00 16.31 ? 434 ASN A ND2 1 ATOM 3234 N N . LEU A 1 402 ? 3.271 18.404 32.988 1.00 20.23 ? 435 LEU A N 1 ATOM 3235 C CA . LEU A 1 402 ? 3.528 18.330 31.577 1.00 20.76 ? 435 LEU A CA 1 ATOM 3236 C C . LEU A 1 402 ? 4.882 17.752 31.225 1.00 23.92 ? 435 LEU A C 1 ATOM 3237 O O . LEU A 1 402 ? 5.058 17.198 30.152 1.00 21.69 ? 435 LEU A O 1 ATOM 3238 C CB . LEU A 1 402 ? 3.374 19.701 30.958 1.00 20.82 ? 435 LEU A CB 1 ATOM 3239 C CG . LEU A 1 402 ? 1.949 20.122 30.667 1.00 21.16 ? 435 LEU A CG 1 ATOM 3240 C CD1 . LEU A 1 402 ? 1.158 20.226 31.949 1.00 21.54 ? 435 LEU A CD1 1 ATOM 3241 C CD2 . LEU A 1 402 ? 1.960 21.430 29.940 1.00 21.42 ? 435 LEU A CD2 1 ATOM 3242 N N . ASP A 1 403 ? 5.866 17.932 32.095 1.00 29.16 ? 436 ASP A N 1 ATOM 3243 C CA . ASP A 1 403 ? 7.199 17.357 31.845 1.00 31.41 ? 436 ASP A CA 1 ATOM 3244 C C . ASP A 1 403 ? 7.373 16.028 32.548 1.00 30.37 ? 436 ASP A C 1 ATOM 3245 O O . ASP A 1 403 ? 6.568 15.641 33.366 1.00 29.77 ? 436 ASP A O 1 ATOM 3246 C CB . ASP A 1 403 ? 8.257 18.313 32.314 1.00 36.49 ? 436 ASP A CB 1 ATOM 3247 C CG . ASP A 1 403 ? 8.264 18.436 33.789 1.00 38.45 ? 436 ASP A CG 1 ATOM 3248 O OD1 . ASP A 1 403 ? 8.873 17.565 34.409 1.00 42.60 ? 436 ASP A OD1 1 ATOM 3249 O OD2 . ASP A 1 403 ? 7.598 19.347 34.315 1.00 46.93 -1 436 ASP A OD2 1 ATOM 3250 N N . ASN A 1 404 ? 8.439 15.337 32.208 1.00 33.74 ? 437 ASN A N 1 ATOM 3251 C CA . ASN A 1 404 ? 8.722 13.977 32.723 1.00 36.17 ? 437 ASN A CA 1 ATOM 3252 C C . ASN A 1 404 ? 8.757 13.758 34.266 1.00 32.87 ? 437 ASN A C 1 ATOM 3253 O O . ASN A 1 404 ? 8.191 12.788 34.792 1.00 28.87 ? 437 ASN A O 1 ATOM 3254 C CB . ASN A 1 404 ? 10.027 13.430 32.085 1.00 41.32 ? 437 ASN A CB 1 ATOM 3255 C CG . ASN A 1 404 ? 11.201 14.466 32.033 1.00 46.10 ? 437 ASN A CG 1 ATOM 3256 O OD1 . ASN A 1 404 ? 12.088 14.326 31.180 1.00 52.96 ? 437 ASN A OD1 1 ATOM 3257 N ND2 . ASN A 1 404 ? 11.215 15.489 32.905 1.00 43.03 ? 437 ASN A ND2 1 ATOM 3258 N N . ILE A 1 405 ? 9.382 14.668 34.989 1.00 30.54 ? 438 ILE A N 1 ATOM 3259 C CA . ILE A 1 405 ? 9.675 14.418 36.381 1.00 34.45 ? 438 ILE A CA 1 ATOM 3260 C C . ILE A 1 405 ? 8.369 14.526 37.188 1.00 33.91 ? 438 ILE A C 1 ATOM 3261 O O . ILE A 1 405 ? 7.980 13.594 37.937 1.00 31.96 ? 438 ILE A O 1 ATOM 3262 C CB . ILE A 1 405 ? 10.708 15.439 36.957 1.00 35.79 ? 438 ILE A CB 1 ATOM 3263 C CG1 . ILE A 1 405 ? 12.012 15.462 36.150 1.00 37.24 ? 438 ILE A CG1 1 ATOM 3264 C CG2 . ILE A 1 405 ? 11.003 15.125 38.420 1.00 36.55 ? 438 ILE A CG2 1 ATOM 3265 C CD1 . ILE A 1 405 ? 13.053 14.444 36.557 1.00 36.99 ? 438 ILE A CD1 1 ATOM 3266 N N . SER A 1 406 ? 7.758 15.706 37.068 1.00 29.15 ? 439 SER A N 1 ATOM 3267 C CA . SER A 1 406 ? 6.446 16.000 37.607 1.00 29.30 ? 439 SER A CA 1 ATOM 3268 C C . SER A 1 406 ? 5.392 14.914 37.361 1.00 27.74 ? 439 SER A C 1 ATOM 3269 O O . SER A 1 406 ? 4.571 14.632 38.229 1.00 24.88 ? 439 SER A O 1 ATOM 3270 C CB . SER A 1 406 ? 5.947 17.281 36.937 1.00 30.58 ? 439 SER A CB 1 ATOM 3271 O OG . SER A 1 406 ? 6.261 18.385 37.743 1.00 36.10 ? 439 SER A OG 1 ATOM 3272 N N . TYR A 1 407 ? 5.389 14.359 36.144 1.00 24.16 ? 440 TYR A N 1 ATOM 3273 C CA . TYR A 1 407 ? 4.345 13.460 35.747 1.00 22.48 ? 440 TYR A CA 1 ATOM 3274 C C . TYR A 1 407 ? 4.526 12.175 36.474 1.00 23.53 ? 440 TYR A C 1 ATOM 3275 O O . TYR A 1 407 ? 3.603 11.678 37.071 1.00 23.98 ? 440 TYR A O 1 ATOM 3276 C CB . TYR A 1 407 ? 4.378 13.225 34.268 1.00 21.32 ? 440 TYR A CB 1 ATOM 3277 C CG . TYR A 1 407 ? 3.364 12.264 33.845 1.00 21.42 ? 440 TYR A CG 1 ATOM 3278 C CD1 . TYR A 1 407 ? 2.042 12.653 33.686 1.00 21.68 ? 440 TYR A CD1 1 ATOM 3279 C CD2 . TYR A 1 407 ? 3.703 10.931 33.584 1.00 22.74 ? 440 TYR A CD2 1 ATOM 3280 C CE1 . TYR A 1 407 ? 1.068 11.743 33.279 1.00 21.15 ? 440 TYR A CE1 1 ATOM 3281 C CE2 . TYR A 1 407 ? 2.739 10.012 33.169 1.00 21.34 ? 440 TYR A CE2 1 ATOM 3282 C CZ . TYR A 1 407 ? 1.425 10.423 33.032 1.00 20.51 ? 440 TYR A CZ 1 ATOM 3283 O OH . TYR A 1 407 ? 0.471 9.531 32.630 1.00 19.82 ? 440 TYR A OH 1 ATOM 3284 N N . ALA A 1 408 ? 5.731 11.633 36.418 1.00 26.65 ? 441 ALA A N 1 ATOM 3285 C CA . ALA A 1 408 ? 6.126 10.484 37.257 1.00 29.39 ? 441 ALA A CA 1 ATOM 3286 C C . ALA A 1 408 ? 5.859 10.733 38.761 1.00 29.27 ? 441 ALA A C 1 ATOM 3287 O O . ALA A 1 408 ? 5.120 10.021 39.440 1.00 29.35 ? 441 ALA A O 1 ATOM 3288 C CB . ALA A 1 408 ? 7.594 10.182 37.022 1.00 31.18 ? 441 ALA A CB 1 ATOM 3289 N N . ASP A 1 409 ? 6.407 11.802 39.266 1.00 30.87 ? 442 ASP A N 1 ATOM 3290 C CA . ASP A 1 409 ? 6.121 12.149 40.624 1.00 33.89 ? 442 ASP A CA 1 ATOM 3291 C C . ASP A 1 409 ? 4.631 12.028 40.919 1.00 32.42 ? 442 ASP A C 1 ATOM 3292 O O . ASP A 1 409 ? 4.252 11.535 41.986 1.00 36.00 ? 442 ASP A O 1 ATOM 3293 C CB . ASP A 1 409 ? 6.616 13.550 40.907 1.00 37.71 ? 442 ASP A CB 1 ATOM 3294 C CG . ASP A 1 409 ? 6.336 13.965 42.311 1.00 43.89 ? 442 ASP A CG 1 ATOM 3295 O OD1 . ASP A 1 409 ? 7.295 13.994 43.114 1.00 49.60 ? 442 ASP A OD1 1 ATOM 3296 O OD2 . ASP A 1 409 ? 5.151 14.233 42.614 1.00 48.76 -1 442 ASP A OD2 1 ATOM 3297 N N . CYS A 1 410 ? 3.791 12.508 40.001 1.00 29.51 ? 443 CYS A N 1 ATOM 3298 C CA . CYS A 1 410 ? 2.326 12.324 40.086 1.00 27.05 ? 443 CYS A CA 1 ATOM 3299 C C . CYS A 1 410 ? 2.074 10.869 39.681 1.00 29.01 ? 443 CYS A C 1 ATOM 3300 O O . CYS A 1 410 ? 1.429 10.118 40.412 1.00 32.09 ? 443 CYS A O 1 ATOM 3301 C CB . CYS A 1 410 ? 1.583 13.307 39.132 1.00 24.22 ? 443 CYS A CB 1 ATOM 3302 S SG . CYS A 1 410 ? -0.225 13.541 39.308 1.00 19.50 ? 443 CYS A SG 1 ATOM 3303 N N . PRO B 1 1 ? -27.396 33.759 30.073 1.00 47.25 ? 34 PRO B N 1 ATOM 3304 C CA . PRO B 1 1 ? -27.594 33.025 28.766 1.00 46.62 ? 34 PRO B CA 1 ATOM 3305 C C . PRO B 1 1 ? -26.792 33.596 27.561 1.00 38.93 ? 34 PRO B C 1 ATOM 3306 O O . PRO B 1 1 ? -27.056 34.723 27.153 1.00 40.39 ? 34 PRO B O 1 ATOM 3307 C CB . PRO B 1 1 ? -29.113 33.149 28.500 1.00 44.78 ? 34 PRO B CB 1 ATOM 3308 C CG . PRO B 1 1 ? -29.479 34.411 29.239 1.00 48.54 ? 34 PRO B CG 1 ATOM 3309 C CD . PRO B 1 1 ? -28.613 34.474 30.493 1.00 45.67 ? 34 PRO B CD 1 ATOM 3310 N N . PRO B 1 2 ? -25.906 32.783 26.941 1.00 35.57 ? 35 PRO B N 1 ATOM 3311 C CA . PRO B 1 2 ? -24.773 33.141 26.041 1.00 33.89 ? 35 PRO B CA 1 ATOM 3312 C C . PRO B 1 2 ? -25.109 33.817 24.714 1.00 31.74 ? 35 PRO B C 1 ATOM 3313 O O . PRO B 1 2 ? -24.319 34.630 24.245 1.00 31.41 ? 35 PRO B O 1 ATOM 3314 C CB . PRO B 1 2 ? -24.129 31.794 25.762 1.00 35.40 ? 35 PRO B CB 1 ATOM 3315 C CG . PRO B 1 2 ? -25.280 30.861 25.797 1.00 35.24 ? 35 PRO B CG 1 ATOM 3316 C CD . PRO B 1 2 ? -26.148 31.329 26.911 1.00 36.10 ? 35 PRO B CD 1 ATOM 3317 N N . ALA B 1 3 ? -26.242 33.445 24.117 1.00 28.60 ? 36 ALA B N 1 ATOM 3318 C CA . ALA B 1 3 ? -26.852 34.185 23.037 1.00 26.78 ? 36 ALA B CA 1 ATOM 3319 C C . ALA B 1 3 ? -28.388 34.273 23.235 1.00 26.56 ? 36 ALA B C 1 ATOM 3320 O O . ALA B 1 3 ? -28.999 33.529 24.032 1.00 26.48 ? 36 ALA B O 1 ATOM 3321 C CB . ALA B 1 3 ? -26.509 33.558 21.705 1.00 26.49 ? 36 ALA B CB 1 ATOM 3322 N N . ILE B 1 4 ? -28.992 35.214 22.518 1.00 25.55 ? 37 ILE B N 1 ATOM 3323 C CA . ILE B 1 4 ? -30.420 35.538 22.664 1.00 24.48 ? 37 ILE B CA 1 ATOM 3324 C C . ILE B 1 4 ? -31.060 35.394 21.306 1.00 21.43 ? 37 ILE B C 1 ATOM 3325 O O . ILE B 1 4 ? -30.564 35.995 20.338 1.00 18.70 ? 37 ILE B O 1 ATOM 3326 C CB . ILE B 1 4 ? -30.682 36.987 23.067 1.00 26.02 ? 37 ILE B CB 1 ATOM 3327 C CG1 . ILE B 1 4 ? -29.930 37.378 24.354 1.00 29.54 ? 37 ILE B CG1 1 ATOM 3328 C CG2 . ILE B 1 4 ? -32.161 37.169 23.270 1.00 26.80 ? 37 ILE B CG2 1 ATOM 3329 C CD1 . ILE B 1 4 ? -30.540 36.869 25.670 1.00 30.26 ? 37 ILE B CD1 1 ATOM 3330 N N . GLY B 1 5 ? -32.124 34.573 21.245 1.00 19.07 ? 38 GLY B N 1 ATOM 3331 C CA . GLY B 1 5 ? -32.937 34.442 20.058 1.00 17.94 ? 38 GLY B CA 1 ATOM 3332 C C . GLY B 1 5 ? -33.873 35.632 19.936 1.00 16.60 ? 38 GLY B C 1 ATOM 3333 O O . GLY B 1 5 ? -34.291 36.188 20.912 1.00 14.81 ? 38 GLY B O 1 ATOM 3334 N N . GLN B 1 6 ? -34.145 36.042 18.715 1.00 17.26 ? 39 GLN B N 1 ATOM 3335 C CA . GLN B 1 6 ? -35.233 36.994 18.424 1.00 17.16 ? 39 GLN B CA 1 ATOM 3336 C C . GLN B 1 6 ? -36.101 36.712 17.150 1.00 16.41 ? 39 GLN B C 1 ATOM 3337 O O . GLN B 1 6 ? -35.635 36.298 16.101 1.00 15.94 ? 39 GLN B O 1 ATOM 3338 C CB . GLN B 1 6 ? -34.666 38.404 18.371 1.00 15.99 ? 39 GLN B CB 1 ATOM 3339 C CG . GLN B 1 6 ? -33.800 38.790 19.584 1.00 15.59 ? 39 GLN B CG 1 ATOM 3340 C CD . GLN B 1 6 ? -33.497 40.281 19.620 1.00 15.24 ? 39 GLN B CD 1 ATOM 3341 O OE1 . GLN B 1 6 ? -33.498 41.006 18.580 1.00 15.31 ? 39 GLN B OE1 1 ATOM 3342 N NE2 . GLN B 1 6 ? -33.174 40.743 20.788 1.00 15.95 ? 39 GLN B NE2 1 ATOM 3343 N N . PHE B 1 7 ? -37.387 36.975 17.283 1.00 17.63 ? 40 PHE B N 1 ATOM 3344 C CA . PHE B 1 7 ? -38.343 36.887 16.162 1.00 17.46 ? 40 PHE B CA 1 ATOM 3345 C C . PHE B 1 7 ? -39.430 37.960 16.274 1.00 17.55 ? 40 PHE B C 1 ATOM 3346 O O . PHE B 1 7 ? -39.981 38.251 17.363 1.00 18.15 ? 40 PHE B O 1 ATOM 3347 C CB . PHE B 1 7 ? -38.993 35.475 16.095 1.00 16.93 ? 40 PHE B CB 1 ATOM 3348 C CG . PHE B 1 7 ? -39.950 35.154 17.240 1.00 16.67 ? 40 PHE B CG 1 ATOM 3349 C CD1 . PHE B 1 7 ? -39.484 34.658 18.401 1.00 17.14 ? 40 PHE B CD1 1 ATOM 3350 C CD2 . PHE B 1 7 ? -41.344 35.292 17.076 1.00 16.91 ? 40 PHE B CD2 1 ATOM 3351 C CE1 . PHE B 1 7 ? -40.383 34.265 19.377 1.00 19.18 ? 40 PHE B CE1 1 ATOM 3352 C CE2 . PHE B 1 7 ? -42.244 34.964 18.029 1.00 16.08 ? 40 PHE B CE2 1 ATOM 3353 C CZ . PHE B 1 7 ? -41.775 34.454 19.190 1.00 19.02 ? 40 PHE B CZ 1 ATOM 3354 N N . TRP B 1 8 ? -39.760 38.534 15.132 1.00 18.02 ? 41 TRP B N 1 ATOM 3355 C CA . TRP B 1 8 ? -40.803 39.578 15.059 1.00 17.96 ? 41 TRP B CA 1 ATOM 3356 C C . TRP B 1 8 ? -42.146 38.912 15.046 1.00 18.01 ? 41 TRP B C 1 ATOM 3357 O O . TRP B 1 8 ? -42.299 37.781 14.537 1.00 20.10 ? 41 TRP B O 1 ATOM 3358 C CB . TRP B 1 8 ? -40.652 40.381 13.754 1.00 17.57 ? 41 TRP B CB 1 ATOM 3359 C CG . TRP B 1 8 ? -39.360 41.196 13.646 1.00 17.32 ? 41 TRP B CG 1 ATOM 3360 C CD1 . TRP B 1 8 ? -38.232 40.848 12.985 1.00 16.94 ? 41 TRP B CD1 1 ATOM 3361 C CD2 . TRP B 1 8 ? -39.103 42.479 14.232 1.00 16.51 ? 41 TRP B CD2 1 ATOM 3362 N NE1 . TRP B 1 8 ? -37.293 41.822 13.145 1.00 17.13 ? 41 TRP B NE1 1 ATOM 3363 C CE2 . TRP B 1 8 ? -37.816 42.836 13.886 1.00 15.46 ? 41 TRP B CE2 1 ATOM 3364 C CE3 . TRP B 1 8 ? -39.852 43.343 15.023 1.00 17.10 ? 41 TRP B CE3 1 ATOM 3365 C CZ2 . TRP B 1 8 ? -37.261 43.980 14.270 1.00 15.81 ? 41 TRP B CZ2 1 ATOM 3366 C CZ3 . TRP B 1 8 ? -39.291 44.486 15.432 1.00 17.52 ? 41 TRP B CZ3 1 ATOM 3367 C CH2 . TRP B 1 8 ? -38.006 44.807 15.052 1.00 17.76 ? 41 TRP B CH2 1 ATOM 3368 N N . HIS B 1 9 ? -43.138 39.587 15.570 1.00 17.89 ? 42 HIS B N 1 ATOM 3369 C CA . HIS B 1 9 ? -44.522 39.164 15.306 1.00 17.50 ? 42 HIS B CA 1 ATOM 3370 C C . HIS B 1 9 ? -45.281 40.290 14.635 1.00 16.77 ? 42 HIS B C 1 ATOM 3371 O O . HIS B 1 9 ? -45.446 41.352 15.225 1.00 16.13 ? 42 HIS B O 1 ATOM 3372 C CB . HIS B 1 9 ? -45.215 38.706 16.591 1.00 17.93 ? 42 HIS B CB 1 ATOM 3373 C CG . HIS B 1 9 ? -46.575 38.101 16.388 1.00 19.37 ? 42 HIS B CG 1 ATOM 3374 N ND1 . HIS B 1 9 ? -47.291 37.539 17.432 1.00 19.83 ? 42 HIS B ND1 1 ATOM 3375 C CD2 . HIS B 1 9 ? -47.369 38.025 15.289 1.00 18.43 ? 42 HIS B CD2 1 ATOM 3376 C CE1 . HIS B 1 9 ? -48.450 37.111 16.973 1.00 20.95 ? 42 HIS B CE1 1 ATOM 3377 N NE2 . HIS B 1 9 ? -48.520 37.415 15.680 1.00 21.68 ? 42 HIS B NE2 1 ATOM 3378 N N . VAL B 1 10 ? -45.741 40.036 13.402 1.00 17.32 ? 43 VAL B N 1 ATOM 3379 C CA . VAL B 1 10 ? -46.645 40.965 12.687 1.00 18.58 ? 43 VAL B CA 1 ATOM 3380 C C . VAL B 1 10 ? -48.030 40.374 12.428 1.00 17.16 ? 43 VAL B C 1 ATOM 3381 O O . VAL B 1 10 ? -48.186 39.146 12.156 1.00 16.29 ? 43 VAL B O 1 ATOM 3382 C CB . VAL B 1 10 ? -46.039 41.528 11.350 1.00 21.04 ? 43 VAL B CB 1 ATOM 3383 C CG1 . VAL B 1 10 ? -44.879 42.483 11.658 1.00 22.02 ? 43 VAL B CG1 1 ATOM 3384 C CG2 . VAL B 1 10 ? -45.604 40.405 10.443 1.00 21.65 ? 43 VAL B CG2 1 ATOM 3385 N N . THR B 1 11 ? -49.051 41.254 12.530 1.00 15.91 ? 44 THR B N 1 ATOM 3386 C CA . THR B 1 11 ? -50.439 40.755 12.344 1.00 14.84 ? 44 THR B CA 1 ATOM 3387 C C . THR B 1 11 ? -51.462 41.764 11.818 1.00 14.75 ? 44 THR B C 1 ATOM 3388 O O . THR B 1 11 ? -51.313 42.979 12.084 1.00 14.43 ? 44 THR B O 1 ATOM 3389 C CB . THR B 1 11 ? -50.984 40.125 13.634 1.00 13.03 ? 44 THR B CB 1 ATOM 3390 O OG1 . THR B 1 11 ? -52.094 39.318 13.309 1.00 12.33 ? 44 THR B OG1 1 ATOM 3391 C CG2 . THR B 1 11 ? -51.423 41.156 14.593 1.00 12.59 ? 44 THR B CG2 1 ATOM 3392 N N . ASP B 1 12 ? -52.504 41.232 11.141 1.00 13.30 ? 45 ASP B N 1 ATOM 3393 C CA . ASP B 1 12 ? -53.664 42.041 10.766 1.00 14.04 ? 45 ASP B CA 1 ATOM 3394 C C . ASP B 1 12 ? -53.259 43.387 10.086 1.00 14.49 ? 45 ASP B C 1 ATOM 3395 O O . ASP B 1 12 ? -53.639 44.522 10.505 1.00 14.15 ? 45 ASP B O 1 ATOM 3396 C CB . ASP B 1 12 ? -54.545 42.286 11.972 1.00 13.89 ? 45 ASP B CB 1 ATOM 3397 C CG . ASP B 1 12 ? -54.974 41.025 12.641 1.00 12.42 ? 45 ASP B CG 1 ATOM 3398 O OD1 . ASP B 1 12 ? -54.432 40.625 13.609 1.00 10.88 ? 45 ASP B OD1 1 ATOM 3399 O OD2 . ASP B 1 12 ? -55.915 40.437 12.188 1.00 13.66 -1 45 ASP B OD2 1 ATOM 3400 N N . LEU B 1 13 ? -52.528 43.208 8.972 1.00 15.21 ? 46 LEU B N 1 ATOM 3401 C CA . LEU B 1 13 ? -51.977 44.308 8.166 1.00 15.02 ? 46 LEU B CA 1 ATOM 3402 C C . LEU B 1 13 ? -53.117 45.098 7.523 1.00 14.46 ? 46 LEU B C 1 ATOM 3403 O O . LEU B 1 13 ? -53.077 46.347 7.537 1.00 12.86 ? 46 LEU B O 1 ATOM 3404 C CB . LEU B 1 13 ? -50.936 43.759 7.145 1.00 14.91 ? 46 LEU B CB 1 ATOM 3405 C CG . LEU B 1 13 ? -49.468 43.527 7.599 1.00 15.31 ? 46 LEU B CG 1 ATOM 3406 C CD1 . LEU B 1 13 ? -49.381 43.291 9.107 1.00 14.92 ? 46 LEU B CD1 1 ATOM 3407 C CD2 . LEU B 1 13 ? -48.771 42.390 6.756 1.00 15.35 ? 46 LEU B CD2 1 ATOM 3408 N N . HIS B 1 14 ? -54.146 44.346 7.037 1.00 14.78 ? 47 HIS B N 1 ATOM 3409 C CA . HIS B 1 14 ? -55.433 44.900 6.490 1.00 15.01 ? 47 HIS B CA 1 ATOM 3410 C C . HIS B 1 14 ? -55.191 46.103 5.511 1.00 15.36 ? 47 HIS B C 1 ATOM 3411 O O . HIS B 1 14 ? -55.701 47.258 5.660 1.00 13.98 ? 47 HIS B O 1 ATOM 3412 C CB . HIS B 1 14 ? -56.362 45.300 7.643 1.00 15.97 ? 47 HIS B CB 1 ATOM 3413 C CG . HIS B 1 14 ? -57.004 44.154 8.366 1.00 16.52 ? 47 HIS B CG 1 ATOM 3414 N ND1 . HIS B 1 14 ? -57.905 43.307 7.768 1.00 16.56 ? 47 HIS B ND1 1 ATOM 3415 C CD2 . HIS B 1 14 ? -56.943 43.768 9.660 1.00 17.88 ? 47 HIS B CD2 1 ATOM 3416 C CE1 . HIS B 1 14 ? -58.333 42.420 8.643 1.00 16.57 ? 47 HIS B CE1 1 ATOM 3417 N NE2 . HIS B 1 14 ? -57.782 42.693 9.804 1.00 17.23 ? 47 HIS B NE2 1 ATOM 3418 N N . LEU B 1 15 ? -54.372 45.797 4.507 1.00 16.39 ? 48 LEU B N 1 ATOM 3419 C CA . LEU B 1 15 ? -54.094 46.717 3.406 1.00 17.23 ? 48 LEU B CA 1 ATOM 3420 C C . LEU B 1 15 ? -55.407 47.212 2.816 1.00 17.51 ? 48 LEU B C 1 ATOM 3421 O O . LEU B 1 15 ? -56.265 46.381 2.488 1.00 15.03 ? 48 LEU B O 1 ATOM 3422 C CB . LEU B 1 15 ? -53.288 46.018 2.304 1.00 16.51 ? 48 LEU B CB 1 ATOM 3423 C CG . LEU B 1 15 ? -53.105 46.859 1.050 1.00 16.65 ? 48 LEU B CG 1 ATOM 3424 C CD1 . LEU B 1 15 ? -52.142 47.994 1.365 1.00 17.24 ? 48 LEU B CD1 1 ATOM 3425 C CD2 . LEU B 1 15 ? -52.545 45.970 -0.036 1.00 17.31 ? 48 LEU B CD2 1 ATOM 3426 N N . ASP B 1 16 ? -55.563 48.544 2.742 1.00 19.23 ? 49 ASP B N 1 ATOM 3427 C CA . ASP B 1 16 ? -56.603 49.144 1.892 1.00 21.37 ? 49 ASP B CA 1 ATOM 3428 C C . ASP B 1 16 ? -56.030 49.684 0.598 1.00 20.63 ? 49 ASP B C 1 ATOM 3429 O O . ASP B 1 16 ? -55.529 50.821 0.563 1.00 19.18 ? 49 ASP B O 1 ATOM 3430 C CB . ASP B 1 16 ? -57.414 50.240 2.620 1.00 23.94 ? 49 ASP B CB 1 ATOM 3431 C CG . ASP B 1 16 ? -58.772 50.562 1.897 1.00 24.22 ? 49 ASP B CG 1 ATOM 3432 O OD1 . ASP B 1 16 ? -58.858 50.268 0.680 1.00 23.61 ? 49 ASP B OD1 1 ATOM 3433 O OD2 . ASP B 1 16 ? -59.737 51.087 2.558 1.00 22.82 -1 49 ASP B OD2 1 ATOM 3434 N N . PRO B 1 17 ? -56.159 48.896 -0.491 1.00 22.32 ? 50 PRO B N 1 ATOM 3435 C CA . PRO B 1 17 ? -55.560 49.326 -1.766 1.00 22.45 ? 50 PRO B CA 1 ATOM 3436 C C . PRO B 1 17 ? -56.221 50.569 -2.337 1.00 22.25 ? 50 PRO B C 1 ATOM 3437 O O . PRO B 1 17 ? -55.651 51.231 -3.141 1.00 25.39 ? 50 PRO B O 1 ATOM 3438 C CB . PRO B 1 17 ? -55.739 48.113 -2.693 1.00 22.60 ? 50 PRO B CB 1 ATOM 3439 C CG . PRO B 1 17 ? -56.453 47.067 -1.902 1.00 22.91 ? 50 PRO B CG 1 ATOM 3440 C CD . PRO B 1 17 ? -57.052 47.735 -0.687 1.00 22.31 ? 50 PRO B CD 1 ATOM 3441 N N . THR B 1 18 ? -57.397 50.922 -1.867 1.00 24.02 ? 51 THR B N 1 ATOM 3442 C CA . THR B 1 18 ? -58.070 52.146 -2.261 1.00 22.19 ? 51 THR B CA 1 ATOM 3443 C C . THR B 1 18 ? -57.500 53.403 -1.637 1.00 21.46 ? 51 THR B C 1 ATOM 3444 O O . THR B 1 18 ? -57.824 54.496 -2.100 1.00 19.66 ? 51 THR B O 1 ATOM 3445 C CB . THR B 1 18 ? -59.535 52.058 -1.850 1.00 24.68 ? 51 THR B CB 1 ATOM 3446 O OG1 . THR B 1 18 ? -60.145 50.946 -2.537 1.00 23.80 ? 51 THR B OG1 1 ATOM 3447 C CG2 . THR B 1 18 ? -60.266 53.317 -2.256 1.00 31.08 ? 51 THR B CG2 1 ATOM 3448 N N . TYR B 1 19 ? -56.679 53.295 -0.581 1.00 21.61 ? 52 TYR B N 1 ATOM 3449 C CA . TYR B 1 19 ? -56.388 54.498 0.236 1.00 21.61 ? 52 TYR B CA 1 ATOM 3450 C C . TYR B 1 19 ? -55.714 55.569 -0.628 1.00 23.25 ? 52 TYR B C 1 ATOM 3451 O O . TYR B 1 19 ? -54.746 55.292 -1.330 1.00 23.09 ? 52 TYR B O 1 ATOM 3452 C CB . TYR B 1 19 ? -55.511 54.206 1.480 1.00 20.66 ? 52 TYR B CB 1 ATOM 3453 C CG . TYR B 1 19 ? -55.449 55.348 2.498 1.00 19.41 ? 52 TYR B CG 1 ATOM 3454 C CD1 . TYR B 1 19 ? -54.613 56.458 2.314 1.00 19.69 ? 52 TYR B CD1 1 ATOM 3455 C CD2 . TYR B 1 19 ? -56.203 55.321 3.656 1.00 20.07 ? 52 TYR B CD2 1 ATOM 3456 C CE1 . TYR B 1 19 ? -54.578 57.511 3.253 1.00 18.36 ? 52 TYR B CE1 1 ATOM 3457 C CE2 . TYR B 1 19 ? -56.161 56.378 4.591 1.00 19.23 ? 52 TYR B CE2 1 ATOM 3458 C CZ . TYR B 1 19 ? -55.374 57.461 4.369 1.00 17.71 ? 52 TYR B CZ 1 ATOM 3459 O OH . TYR B 1 19 ? -55.380 58.470 5.302 1.00 17.39 ? 52 TYR B OH 1 ATOM 3460 N N . HIS B 1 20 ? -56.228 56.792 -0.560 1.00 24.49 ? 53 HIS B N 1 ATOM 3461 C CA . HIS B 1 20 ? -55.540 57.931 -1.138 1.00 25.15 ? 53 HIS B CA 1 ATOM 3462 C C . HIS B 1 20 ? -56.143 59.235 -0.595 1.00 24.81 ? 53 HIS B C 1 ATOM 3463 O O . HIS B 1 20 ? -57.363 59.354 -0.396 1.00 21.93 ? 53 HIS B O 1 ATOM 3464 C CB . HIS B 1 20 ? -55.620 57.902 -2.671 1.00 26.63 ? 53 HIS B CB 1 ATOM 3465 C CG . HIS B 1 20 ? -56.988 58.174 -3.183 1.00 28.44 ? 53 HIS B CG 1 ATOM 3466 N ND1 . HIS B 1 20 ? -58.056 57.341 -2.916 1.00 30.47 ? 53 HIS B ND1 1 ATOM 3467 C CD2 . HIS B 1 20 ? -57.490 59.228 -3.863 1.00 30.42 ? 53 HIS B CD2 1 ATOM 3468 C CE1 . HIS B 1 20 ? -59.153 57.851 -3.447 1.00 30.69 ? 53 HIS B CE1 1 ATOM 3469 N NE2 . HIS B 1 20 ? -58.839 59.002 -4.016 1.00 32.05 ? 53 HIS B NE2 1 ATOM 3470 N N . ILE B 1 21 ? -55.253 60.194 -0.370 1.00 26.05 ? 54 ILE B N 1 ATOM 3471 C CA . ILE B 1 21 ? -55.613 61.509 0.061 1.00 29.29 ? 54 ILE B CA 1 ATOM 3472 C C . ILE B 1 21 ? -56.345 62.297 -1.048 1.00 32.13 ? 54 ILE B C 1 ATOM 3473 O O . ILE B 1 21 ? -55.851 62.464 -2.168 1.00 30.38 ? 54 ILE B O 1 ATOM 3474 C CB . ILE B 1 21 ? -54.371 62.291 0.557 1.00 30.93 ? 54 ILE B CB 1 ATOM 3475 C CG1 . ILE B 1 21 ? -53.724 61.577 1.773 1.00 31.03 ? 54 ILE B CG1 1 ATOM 3476 C CG2 . ILE B 1 21 ? -54.741 63.739 0.907 1.00 31.05 ? 54 ILE B CG2 1 ATOM 3477 C CD1 . ILE B 1 21 ? -54.622 61.489 2.995 1.00 30.26 ? 54 ILE B CD1 1 ATOM 3478 N N . THR B 1 22 ? -57.536 62.767 -0.679 1.00 34.79 ? 55 THR B N 1 ATOM 3479 C CA . THR B 1 22 ? -58.388 63.572 -1.513 1.00 34.32 ? 55 THR B CA 1 ATOM 3480 C C . THR B 1 22 ? -59.342 64.412 -0.657 1.00 36.73 ? 55 THR B C 1 ATOM 3481 O O . THR B 1 22 ? -59.539 64.156 0.550 1.00 36.74 ? 55 THR B O 1 ATOM 3482 C CB . THR B 1 22 ? -59.195 62.686 -2.465 1.00 36.11 ? 55 THR B CB 1 ATOM 3483 O OG1 . THR B 1 22 ? -59.981 63.510 -3.320 1.00 38.84 ? 55 THR B OG1 1 ATOM 3484 C CG2 . THR B 1 22 ? -60.133 61.726 -1.692 1.00 36.58 ? 55 THR B CG2 1 ATOM 3485 N N . ASP B 1 23 ? -59.963 65.395 -1.310 1.00 40.32 ? 56 ASP B N 1 ATOM 3486 C CA . ASP B 1 23 ? -60.823 66.395 -0.646 1.00 40.69 ? 56 ASP B CA 1 ATOM 3487 C C . ASP B 1 23 ? -62.160 65.864 -0.098 1.00 35.84 ? 56 ASP B C 1 ATOM 3488 O O . ASP B 1 23 ? -62.655 66.371 0.905 1.00 32.69 ? 56 ASP B O 1 ATOM 3489 C CB . ASP B 1 23 ? -61.085 67.562 -1.606 1.00 46.72 ? 56 ASP B CB 1 ATOM 3490 C CG . ASP B 1 23 ? -59.906 68.518 -1.696 1.00 53.51 ? 56 ASP B CG 1 ATOM 3491 O OD1 . ASP B 1 23 ? -59.314 68.786 -0.625 1.00 55.76 ? 56 ASP B OD1 1 ATOM 3492 O OD2 . ASP B 1 23 ? -59.574 68.996 -2.819 1.00 54.04 -1 56 ASP B OD2 1 ATOM 3493 N N . ASP B 1 24 ? -62.741 64.876 -0.778 1.00 31.38 ? 57 ASP B N 1 ATOM 3494 C CA . ASP B 1 24 ? -63.973 64.225 -0.356 1.00 29.07 ? 57 ASP B CA 1 ATOM 3495 C C . ASP B 1 24 ? -63.547 63.101 0.577 1.00 26.31 ? 57 ASP B C 1 ATOM 3496 O O . ASP B 1 24 ? -63.095 62.062 0.116 1.00 24.76 ? 57 ASP B O 1 ATOM 3497 C CB . ASP B 1 24 ? -64.739 63.675 -1.575 1.00 30.31 ? 57 ASP B CB 1 ATOM 3498 C CG . ASP B 1 24 ? -66.108 63.070 -1.213 1.00 32.31 ? 57 ASP B CG 1 ATOM 3499 O OD1 . ASP B 1 24 ? -66.375 62.780 -0.019 1.00 31.79 ? 57 ASP B OD1 1 ATOM 3500 O OD2 . ASP B 1 24 ? -66.937 62.875 -2.142 1.00 33.67 -1 57 ASP B OD2 1 ATOM 3501 N N . HIS B 1 25 ? -63.678 63.342 1.885 1.00 23.95 ? 58 HIS B N 1 ATOM 3502 C CA . HIS B 1 25 ? -63.207 62.430 2.942 1.00 22.99 ? 58 HIS B CA 1 ATOM 3503 C C . HIS B 1 25 ? -64.092 61.172 3.018 1.00 21.34 ? 58 HIS B C 1 ATOM 3504 O O . HIS B 1 25 ? -63.737 60.195 3.679 1.00 20.56 ? 58 HIS B O 1 ATOM 3505 C CB . HIS B 1 25 ? -63.122 63.129 4.346 1.00 24.19 ? 58 HIS B CB 1 ATOM 3506 C CG . HIS B 1 25 ? -61.905 64.000 4.577 1.00 24.65 ? 58 HIS B CG 1 ATOM 3507 N ND1 . HIS B 1 25 ? -60.991 64.329 3.593 1.00 24.11 ? 58 HIS B ND1 1 ATOM 3508 C CD2 . HIS B 1 25 ? -61.496 64.659 5.697 1.00 25.10 ? 58 HIS B CD2 1 ATOM 3509 C CE1 . HIS B 1 25 ? -60.052 65.105 4.109 1.00 23.69 ? 58 HIS B CE1 1 ATOM 3510 N NE2 . HIS B 1 25 ? -60.316 65.292 5.389 1.00 23.30 ? 58 HIS B NE2 1 ATOM 3511 N N . THR B 1 26 ? -65.216 61.156 2.307 1.00 20.90 ? 59 THR B N 1 ATOM 3512 C CA . THR B 1 26 ? -65.963 59.877 2.128 1.00 21.39 ? 59 THR B CA 1 ATOM 3513 C C . THR B 1 26 ? -65.335 58.981 1.046 1.00 22.61 ? 59 THR B C 1 ATOM 3514 O O . THR B 1 26 ? -65.719 57.821 0.919 1.00 27.07 ? 59 THR B O 1 ATOM 3515 C CB . THR B 1 26 ? -67.462 60.060 1.786 1.00 19.47 ? 59 THR B CB 1 ATOM 3516 O OG1 . THR B 1 26 ? -67.594 60.557 0.449 1.00 18.68 ? 59 THR B OG1 1 ATOM 3517 C CG2 . THR B 1 26 ? -68.109 61.012 2.759 1.00 19.60 ? 59 THR B CG2 1 ATOM 3518 N N . LYS B 1 27 ? -64.375 59.499 0.290 1.00 23.64 ? 60 LYS B N 1 ATOM 3519 C CA . LYS B 1 27 ? -63.751 58.759 -0.814 1.00 25.02 ? 60 LYS B CA 1 ATOM 3520 C C . LYS B 1 27 ? -62.258 58.445 -0.556 1.00 23.07 ? 60 LYS B C 1 ATOM 3521 O O . LYS B 1 27 ? -61.585 57.969 -1.462 1.00 25.40 ? 60 LYS B O 1 ATOM 3522 C CB . LYS B 1 27 ? -63.861 59.588 -2.134 1.00 27.33 ? 60 LYS B CB 1 ATOM 3523 C CG . LYS B 1 27 ? -65.274 60.041 -2.576 1.00 30.20 ? 60 LYS B CG 1 ATOM 3524 C CD . LYS B 1 27 ? -65.887 59.102 -3.626 1.00 32.06 ? 60 LYS B CD 1 ATOM 3525 C CE . LYS B 1 27 ? -67.392 59.262 -3.779 1.00 33.52 ? 60 LYS B CE 1 ATOM 3526 N NZ . LYS B 1 27 ? -67.703 60.311 -4.790 1.00 34.80 1 60 LYS B NZ 1 ATOM 3527 N N . VAL B 1 28 ? -61.729 58.750 0.629 1.00 20.34 ? 61 VAL B N 1 ATOM 3528 C CA . VAL B 1 28 ? -60.335 58.390 0.973 1.00 18.84 ? 61 VAL B CA 1 ATOM 3529 C C . VAL B 1 28 ? -60.102 56.883 0.991 1.00 18.71 ? 61 VAL B C 1 ATOM 3530 O O . VAL B 1 28 ? -59.044 56.386 0.520 1.00 18.93 ? 61 VAL B O 1 ATOM 3531 C CB . VAL B 1 28 ? -59.918 59.014 2.328 1.00 18.00 ? 61 VAL B CB 1 ATOM 3532 C CG1 . VAL B 1 28 ? -58.626 58.424 2.915 1.00 16.82 ? 61 VAL B CG1 1 ATOM 3533 C CG2 . VAL B 1 28 ? -59.778 60.514 2.126 1.00 18.78 ? 61 VAL B CG2 1 ATOM 3534 N N . CYS B 1 29 ? -61.080 56.144 1.484 1.00 17.07 ? 62 CYS B N 1 ATOM 3535 C CA . CYS B 1 29 ? -60.848 54.752 1.667 1.00 18.08 ? 62 CYS B CA 1 ATOM 3536 C C . CYS B 1 29 ? -62.145 53.977 1.676 1.00 17.86 ? 62 CYS B C 1 ATOM 3537 O O . CYS B 1 29 ? -63.011 54.244 2.505 1.00 18.67 ? 62 CYS B O 1 ATOM 3538 C CB . CYS B 1 29 ? -60.094 54.547 3.004 1.00 19.93 ? 62 CYS B CB 1 ATOM 3539 S SG . CYS B 1 29 ? -61.008 55.043 4.528 1.00 18.34 ? 62 CYS B SG 1 ATOM 3540 N N . ALA B 1 30 ? -62.258 53.008 0.768 1.00 17.19 ? 63 ALA B N 1 ATOM 3541 C CA . ALA B 1 30 ? -63.362 52.060 0.760 1.00 17.19 ? 63 ALA B CA 1 ATOM 3542 C C . ALA B 1 30 ? -63.681 51.474 2.172 1.00 18.09 ? 63 ALA B C 1 ATOM 3543 O O . ALA B 1 30 ? -64.852 51.401 2.572 1.00 18.01 ? 63 ALA B O 1 ATOM 3544 C CB . ALA B 1 30 ? -63.042 50.945 -0.204 1.00 17.19 ? 63 ALA B CB 1 ATOM 3545 N N . SER B 1 31 ? -62.650 51.076 2.921 1.00 18.09 ? 64 SER B N 1 ATOM 3546 C CA . SER B 1 31 ? -62.798 50.650 4.353 1.00 18.12 ? 64 SER B CA 1 ATOM 3547 C C . SER B 1 31 ? -63.559 51.613 5.344 1.00 17.69 ? 64 SER B C 1 ATOM 3548 O O . SER B 1 31 ? -63.858 51.227 6.490 1.00 16.51 ? 64 SER B O 1 ATOM 3549 C CB . SER B 1 31 ? -61.390 50.297 4.948 1.00 18.02 ? 64 SER B CB 1 ATOM 3550 O OG . SER B 1 31 ? -60.419 51.373 4.896 1.00 16.51 ? 64 SER B OG 1 ATOM 3551 N N . SER B 1 32 ? -63.829 52.867 4.944 1.00 17.18 ? 65 SER B N 1 ATOM 3552 C CA . SER B 1 32 ? -64.690 53.734 5.756 1.00 16.47 ? 65 SER B CA 1 ATOM 3553 C C . SER B 1 32 ? -66.155 53.502 5.406 1.00 17.69 ? 65 SER B C 1 ATOM 3554 O O . SER B 1 32 ? -67.034 54.006 6.075 1.00 17.70 ? 65 SER B O 1 ATOM 3555 C CB . SER B 1 32 ? -64.314 55.201 5.571 1.00 16.57 ? 65 SER B CB 1 ATOM 3556 O OG . SER B 1 32 ? -65.088 55.895 4.601 1.00 16.72 ? 65 SER B OG 1 ATOM 3557 N N . LYS B 1 33 ? -66.415 52.740 4.342 1.00 18.53 ? 66 LYS B N 1 ATOM 3558 C CA . LYS B 1 33 ? -67.782 52.462 3.883 1.00 19.78 ? 66 LYS B CA 1 ATOM 3559 C C . LYS B 1 33 ? -68.622 53.714 3.736 1.00 18.80 ? 66 LYS B C 1 ATOM 3560 O O . LYS B 1 33 ? -69.798 53.731 4.079 1.00 20.27 ? 66 LYS B O 1 ATOM 3561 C CB . LYS B 1 33 ? -68.467 51.422 4.774 1.00 20.43 ? 66 LYS B CB 1 ATOM 3562 C CG . LYS B 1 33 ? -67.735 50.100 4.693 1.00 22.28 ? 66 LYS B CG 1 ATOM 3563 C CD . LYS B 1 33 ? -68.200 49.072 5.695 1.00 24.78 ? 66 LYS B CD 1 ATOM 3564 C CE . LYS B 1 33 ? -66.979 48.353 6.264 1.00 27.17 ? 66 LYS B CE 1 ATOM 3565 N NZ . LYS B 1 33 ? -66.062 49.303 6.977 1.00 27.64 1 66 LYS B NZ 1 ATOM 3566 N N . GLY B 1 34 ? -68.006 54.761 3.228 1.00 17.96 ? 67 GLY B N 1 ATOM 3567 C CA . GLY B 1 34 ? -68.725 55.988 2.962 1.00 19.08 ? 67 GLY B CA 1 ATOM 3568 C C . GLY B 1 34 ? -68.742 56.967 4.111 1.00 20.57 ? 67 GLY B C 1 ATOM 3569 O O . GLY B 1 34 ? -69.171 58.097 3.920 1.00 24.62 ? 67 GLY B O 1 ATOM 3570 N N . ALA B 1 35 ? -68.291 56.583 5.302 1.00 20.84 ? 68 ALA B N 1 ATOM 3571 C CA . ALA B 1 35 ? -68.130 57.578 6.367 1.00 22.44 ? 68 ALA B CA 1 ATOM 3572 C C . ALA B 1 35 ? -66.980 58.541 6.037 1.00 24.03 ? 68 ALA B C 1 ATOM 3573 O O . ALA B 1 35 ? -66.046 58.196 5.277 1.00 24.97 ? 68 ALA B O 1 ATOM 3574 C CB . ALA B 1 35 ? -67.920 56.928 7.713 1.00 22.28 ? 68 ALA B CB 1 ATOM 3575 N N . ASN B 1 36 ? -67.097 59.726 6.570 1.00 22.69 ? 69 ASN B N 1 ATOM 3576 C CA . ASN B 1 36 ? -66.109 60.698 6.362 1.00 22.65 ? 69 ASN B CA 1 ATOM 3577 C C . ASN B 1 36 ? -64.908 60.310 7.173 1.00 21.82 ? 69 ASN B C 1 ATOM 3578 O O . ASN B 1 36 ? -64.948 60.350 8.363 1.00 23.42 ? 69 ASN B O 1 ATOM 3579 C CB . ASN B 1 36 ? -66.655 62.063 6.769 1.00 21.35 ? 69 ASN B CB 1 ATOM 3580 C CG . ASN B 1 36 ? -66.793 62.983 5.624 1.00 23.12 ? 69 ASN B CG 1 ATOM 3581 O OD1 . ASN B 1 36 ? -65.879 63.216 4.977 1.00 22.24 ? 69 ASN B OD1 1 ATOM 3582 N ND2 . ASN B 1 36 ? -67.935 63.518 5.405 1.00 30.41 ? 69 ASN B ND2 1 ATOM 3583 N N . ALA B 1 37 ? -63.833 59.937 6.517 1.00 22.52 ? 70 ALA B N 1 ATOM 3584 C CA . ALA B 1 37 ? -62.622 59.611 7.232 1.00 24.68 ? 70 ALA B CA 1 ATOM 3585 C C . ALA B 1 37 ? -62.305 60.898 8.046 1.00 27.79 ? 70 ALA B C 1 ATOM 3586 O O . ALA B 1 37 ? -62.634 62.013 7.622 1.00 25.55 ? 70 ALA B O 1 ATOM 3587 C CB . ALA B 1 37 ? -61.505 59.168 6.297 1.00 22.97 ? 70 ALA B CB 1 ATOM 3588 N N . SER B 1 38 ? -61.768 60.688 9.244 1.00 29.36 ? 71 SER B N 1 ATOM 3589 C CA . SER B 1 38 ? -61.611 61.676 10.311 1.00 30.95 ? 71 SER B CA 1 ATOM 3590 C C . SER B 1 38 ? -60.618 62.831 10.107 1.00 31.29 ? 71 SER B C 1 ATOM 3591 O O . SER B 1 38 ? -60.957 64.000 10.203 1.00 32.46 ? 71 SER B O 1 ATOM 3592 C CB . SER B 1 38 ? -61.310 60.877 11.599 1.00 33.65 ? 71 SER B CB 1 ATOM 3593 O OG . SER B 1 38 ? -61.224 61.662 12.771 1.00 36.63 ? 71 SER B OG 1 ATOM 3594 N N . ASN B 1 39 ? -59.379 62.474 9.871 1.00 30.45 ? 72 ASN B N 1 ATOM 3595 C CA . ASN B 1 39 ? -58.274 63.420 9.647 1.00 31.80 ? 72 ASN B CA 1 ATOM 3596 C C . ASN B 1 39 ? -57.177 62.684 8.839 1.00 27.86 ? 72 ASN B C 1 ATOM 3597 O O . ASN B 1 39 ? -56.085 62.409 9.355 1.00 27.34 ? 72 ASN B O 1 ATOM 3598 C CB . ASN B 1 39 ? -57.744 63.986 10.967 1.00 34.63 ? 72 ASN B CB 1 ATOM 3599 C CG . ASN B 1 39 ? -57.027 65.321 10.802 1.00 38.63 ? 72 ASN B CG 1 ATOM 3600 O OD1 . ASN B 1 39 ? -57.225 66.053 9.826 1.00 43.34 ? 72 ASN B OD1 1 ATOM 3601 N ND2 . ASN B 1 39 ? -56.187 65.642 11.774 1.00 41.82 ? 72 ASN B ND2 1 ATOM 3602 N N . PRO B 1 40 ? -57.487 62.364 7.549 1.00 24.32 ? 73 PRO B N 1 ATOM 3603 C CA . PRO B 1 40 ? -56.687 61.354 6.920 1.00 22.16 ? 73 PRO B CA 1 ATOM 3604 C C . PRO B 1 40 ? -55.354 61.928 6.671 1.00 20.72 ? 73 PRO B C 1 ATOM 3605 O O . PRO B 1 40 ? -55.221 63.128 6.526 1.00 18.55 ? 73 PRO B O 1 ATOM 3606 C CB . PRO B 1 40 ? -57.432 61.072 5.644 1.00 22.63 ? 73 PRO B CB 1 ATOM 3607 C CG . PRO B 1 40 ? -58.077 62.390 5.284 1.00 22.93 ? 73 PRO B CG 1 ATOM 3608 C CD . PRO B 1 40 ? -58.402 63.036 6.585 1.00 23.32 ? 73 PRO B CD 1 ATOM 3609 N N . GLY B 1 41 ? -54.366 61.060 6.700 1.00 20.54 ? 74 GLY B N 1 ATOM 3610 C CA . GLY B 1 41 ? -52.994 61.471 6.484 1.00 20.21 ? 74 GLY B CA 1 ATOM 3611 C C . GLY B 1 41 ? -52.239 60.476 5.644 1.00 19.67 ? 74 GLY B C 1 ATOM 3612 O O . GLY B 1 41 ? -52.771 59.463 5.226 1.00 19.92 ? 74 GLY B O 1 ATOM 3613 N N . PRO B 1 42 ? -50.980 60.764 5.379 1.00 21.12 ? 75 PRO B N 1 ATOM 3614 C CA . PRO B 1 42 ? -50.219 59.879 4.489 1.00 21.25 ? 75 PRO B CA 1 ATOM 3615 C C . PRO B 1 42 ? -49.980 58.502 5.098 1.00 22.65 ? 75 PRO B C 1 ATOM 3616 O O . PRO B 1 42 ? -49.768 57.524 4.371 1.00 25.15 ? 75 PRO B O 1 ATOM 3617 C CB . PRO B 1 42 ? -48.902 60.624 4.299 1.00 21.20 ? 75 PRO B CB 1 ATOM 3618 C CG . PRO B 1 42 ? -48.806 61.573 5.483 1.00 21.69 ? 75 PRO B CG 1 ATOM 3619 C CD . PRO B 1 42 ? -50.207 61.936 5.848 1.00 21.01 ? 75 PRO B CD 1 ATOM 3620 N N . PHE B 1 43 ? -50.027 58.391 6.427 1.00 23.53 ? 76 PHE B N 1 ATOM 3621 C CA . PHE B 1 43 ? -49.849 57.066 7.060 1.00 22.74 ? 76 PHE B CA 1 ATOM 3622 C C . PHE B 1 43 ? -51.106 56.342 7.499 1.00 20.99 ? 76 PHE B C 1 ATOM 3623 O O . PHE B 1 43 ? -50.975 55.237 8.012 1.00 19.93 ? 76 PHE B O 1 ATOM 3624 C CB . PHE B 1 43 ? -48.874 57.153 8.216 1.00 23.49 ? 76 PHE B CB 1 ATOM 3625 C CG . PHE B 1 43 ? -47.514 57.558 7.782 1.00 23.86 ? 76 PHE B CG 1 ATOM 3626 C CD1 . PHE B 1 43 ? -46.710 56.654 7.097 1.00 24.17 ? 76 PHE B CD1 1 ATOM 3627 C CD2 . PHE B 1 43 ? -47.078 58.855 7.975 1.00 23.86 ? 76 PHE B CD2 1 ATOM 3628 C CE1 . PHE B 1 43 ? -45.472 57.033 6.641 1.00 25.17 ? 76 PHE B CE1 1 ATOM 3629 C CE2 . PHE B 1 43 ? -45.839 59.246 7.531 1.00 25.40 ? 76 PHE B CE2 1 ATOM 3630 C CZ . PHE B 1 43 ? -45.033 58.331 6.849 1.00 25.43 ? 76 PHE B CZ 1 ATOM 3631 N N . GLY B 1 44 ? -52.290 56.937 7.271 1.00 18.30 ? 77 GLY B N 1 ATOM 3632 C CA . GLY B 1 44 ? -53.561 56.294 7.616 1.00 18.02 ? 77 GLY B CA 1 ATOM 3633 C C . GLY B 1 44 ? -54.579 57.134 8.392 1.00 17.67 ? 77 GLY B C 1 ATOM 3634 O O . GLY B 1 44 ? -54.473 58.369 8.525 1.00 16.60 ? 77 GLY B O 1 ATOM 3635 N N . ASP B 1 45 ? -55.608 56.468 8.876 1.00 16.32 ? 78 ASP B N 1 ATOM 3636 C CA . ASP B 1 45 ? -56.690 57.191 9.536 1.00 16.36 ? 78 ASP B CA 1 ATOM 3637 C C . ASP B 1 45 ? -57.410 56.133 10.329 1.00 15.06 ? 78 ASP B C 1 ATOM 3638 O O . ASP B 1 45 ? -57.376 54.967 9.915 1.00 12.97 ? 78 ASP B O 1 ATOM 3639 C CB . ASP B 1 45 ? -57.638 57.849 8.508 1.00 16.74 ? 78 ASP B CB 1 ATOM 3640 C CG . ASP B 1 45 ? -58.845 58.602 9.146 1.00 16.86 ? 78 ASP B CG 1 ATOM 3641 O OD1 . ASP B 1 45 ? -58.672 59.796 9.418 1.00 17.87 ? 78 ASP B OD1 1 ATOM 3642 O OD2 . ASP B 1 45 ? -59.971 58.075 9.294 1.00 15.73 -1 78 ASP B OD2 1 ATOM 3643 N N . VAL B 1 46 ? -58.024 56.558 11.450 1.00 15.16 ? 79 VAL B N 1 ATOM 3644 C CA . VAL B 1 46 ? -58.719 55.695 12.425 1.00 14.81 ? 79 VAL B CA 1 ATOM 3645 C C . VAL B 1 46 ? -60.005 55.139 11.828 1.00 14.02 ? 79 VAL B C 1 ATOM 3646 O O . VAL B 1 46 ? -60.460 54.167 12.238 1.00 16.85 ? 79 VAL B O 1 ATOM 3647 C CB . VAL B 1 46 ? -58.970 56.423 13.787 1.00 16.70 ? 79 VAL B CB 1 ATOM 3648 C CG1 . VAL B 1 46 ? -57.667 56.852 14.542 1.00 16.70 ? 79 VAL B CG1 1 ATOM 3649 C CG2 . VAL B 1 46 ? -59.834 57.673 13.641 1.00 17.02 ? 79 VAL B CG2 1 ATOM 3650 N N . LEU B 1 47 ? -60.535 55.709 10.794 1.00 13.19 ? 80 LEU B N 1 ATOM 3651 C CA . LEU B 1 47 ? -61.685 55.173 10.092 1.00 13.56 ? 80 LEU B CA 1 ATOM 3652 C C . LEU B 1 47 ? -61.326 54.384 8.811 1.00 14.21 ? 80 LEU B C 1 ATOM 3653 O O . LEU B 1 47 ? -62.228 53.842 8.100 1.00 11.91 ? 80 LEU B O 1 ATOM 3654 C CB . LEU B 1 47 ? -62.622 56.376 9.732 1.00 13.09 ? 80 LEU B CB 1 ATOM 3655 C CG . LEU B 1 47 ? -63.833 56.688 10.641 1.00 13.14 ? 80 LEU B CG 1 ATOM 3656 C CD1 . LEU B 1 47 ? -63.938 55.955 12.011 1.00 12.71 ? 80 LEU B CD1 1 ATOM 3657 C CD2 . LEU B 1 47 ? -63.914 58.179 10.807 1.00 13.35 ? 80 LEU B CD2 1 ATOM 3658 N N . CYS B 1 48 ? -60.025 54.300 8.530 1.00 15.49 ? 81 CYS B N 1 ATOM 3659 C CA . CYS B 1 48 ? -59.534 53.437 7.418 1.00 18.44 ? 81 CYS B CA 1 ATOM 3660 C C . CYS B 1 48 ? -58.689 52.218 7.834 1.00 18.35 ? 81 CYS B C 1 ATOM 3661 O O . CYS B 1 48 ? -58.041 52.223 8.844 1.00 19.24 ? 81 CYS B O 1 ATOM 3662 C CB . CYS B 1 48 ? -58.711 54.247 6.378 1.00 20.12 ? 81 CYS B CB 1 ATOM 3663 S SG . CYS B 1 48 ? -59.538 55.753 5.810 1.00 21.90 ? 81 CYS B SG 1 ATOM 3664 N N . ASP B 1 49 ? -58.656 51.192 7.000 1.00 18.34 ? 82 ASP B N 1 ATOM 3665 C CA . ASP B 1 49 ? -57.605 50.195 7.092 1.00 17.84 ? 82 ASP B CA 1 ATOM 3666 C C . ASP B 1 49 ? -56.265 50.769 6.586 1.00 16.10 ? 82 ASP B C 1 ATOM 3667 O O . ASP B 1 49 ? -56.232 51.946 6.149 1.00 16.30 ? 82 ASP B O 1 ATOM 3668 C CB . ASP B 1 49 ? -58.042 48.957 6.329 1.00 19.19 ? 82 ASP B CB 1 ATOM 3669 C CG . ASP B 1 49 ? -58.687 47.931 7.265 1.00 20.69 ? 82 ASP B CG 1 ATOM 3670 O OD1 . ASP B 1 49 ? -58.092 47.759 8.386 1.00 22.95 ? 82 ASP B OD1 1 ATOM 3671 O OD2 . ASP B 1 49 ? -59.752 47.325 6.929 1.00 18.67 -1 82 ASP B OD2 1 ATOM 3672 N N . SER B 1 50 ? -55.202 49.975 6.673 1.00 13.73 ? 83 SER B N 1 ATOM 3673 C CA . SER B 1 50 ? -53.815 50.450 6.422 1.00 14.18 ? 83 SER B CA 1 ATOM 3674 C C . SER B 1 50 ? -53.550 50.856 4.946 1.00 16.16 ? 83 SER B C 1 ATOM 3675 O O . SER B 1 50 ? -53.826 50.049 4.021 1.00 16.11 ? 83 SER B O 1 ATOM 3676 C CB . SER B 1 50 ? -52.763 49.340 6.724 1.00 13.48 ? 83 SER B CB 1 ATOM 3677 O OG . SER B 1 50 ? -52.865 48.653 7.956 1.00 11.55 ? 83 SER B OG 1 ATOM 3678 N N . PRO B 1 51 ? -53.035 52.089 4.699 1.00 17.58 ? 84 PRO B N 1 ATOM 3679 C CA . PRO B 1 51 ? -52.454 52.342 3.349 1.00 18.63 ? 84 PRO B CA 1 ATOM 3680 C C . PRO B 1 51 ? -51.155 51.562 3.156 1.00 20.36 ? 84 PRO B C 1 ATOM 3681 O O . PRO B 1 51 ? -50.492 51.217 4.143 1.00 18.99 ? 84 PRO B O 1 ATOM 3682 C CB . PRO B 1 51 ? -52.128 53.840 3.351 1.00 18.38 ? 84 PRO B CB 1 ATOM 3683 C CG . PRO B 1 51 ? -52.319 54.317 4.769 1.00 18.53 ? 84 PRO B CG 1 ATOM 3684 C CD . PRO B 1 51 ? -53.236 53.336 5.454 1.00 17.68 ? 84 PRO B CD 1 ATOM 3685 N N . TYR B 1 52 ? -50.798 51.269 1.906 1.00 22.26 ? 85 TYR B N 1 ATOM 3686 C CA . TYR B 1 52 ? -49.538 50.561 1.633 1.00 23.07 ? 85 TYR B CA 1 ATOM 3687 C C . TYR B 1 52 ? -48.333 51.201 2.328 1.00 20.70 ? 85 TYR B C 1 ATOM 3688 O O . TYR B 1 52 ? -47.491 50.487 2.831 1.00 20.11 ? 85 TYR B O 1 ATOM 3689 C CB . TYR B 1 52 ? -49.266 50.468 0.121 1.00 24.61 ? 85 TYR B CB 1 ATOM 3690 C CG . TYR B 1 52 ? -48.131 49.501 -0.239 1.00 27.20 ? 85 TYR B CG 1 ATOM 3691 C CD1 . TYR B 1 52 ? -48.249 48.124 -0.003 1.00 28.70 ? 85 TYR B CD1 1 ATOM 3692 C CD2 . TYR B 1 52 ? -46.964 49.958 -0.857 1.00 28.93 ? 85 TYR B CD2 1 ATOM 3693 C CE1 . TYR B 1 52 ? -47.230 47.239 -0.348 1.00 30.02 ? 85 TYR B CE1 1 ATOM 3694 C CE2 . TYR B 1 52 ? -45.940 49.082 -1.210 1.00 30.18 ? 85 TYR B CE2 1 ATOM 3695 C CZ . TYR B 1 52 ? -46.070 47.729 -0.941 1.00 30.64 ? 85 TYR B CZ 1 ATOM 3696 O OH . TYR B 1 52 ? -45.061 46.869 -1.270 1.00 28.73 ? 85 TYR B OH 1 ATOM 3697 N N . GLN B 1 53 ? -48.285 52.533 2.349 1.00 18.73 ? 86 GLN B N 1 ATOM 3698 C CA . GLN B 1 53 ? -47.198 53.303 2.910 1.00 19.35 ? 86 GLN B CA 1 ATOM 3699 C C . GLN B 1 53 ? -47.029 53.048 4.438 1.00 19.44 ? 86 GLN B C 1 ATOM 3700 O O . GLN B 1 53 ? -45.913 53.148 5.014 1.00 18.36 ? 86 GLN B O 1 ATOM 3701 C CB . GLN B 1 53 ? -47.480 54.791 2.603 1.00 22.90 ? 86 GLN B CB 1 ATOM 3702 C CG . GLN B 1 53 ? -46.469 55.800 3.128 1.00 28.77 ? 86 GLN B CG 1 ATOM 3703 C CD . GLN B 1 53 ? -46.368 57.063 2.251 1.00 39.20 ? 86 GLN B CD 1 ATOM 3704 O OE1 . GLN B 1 53 ? -45.519 57.152 1.342 1.00 48.83 ? 86 GLN B OE1 1 ATOM 3705 N NE2 . GLN B 1 53 ? -47.245 58.038 2.498 1.00 42.76 ? 86 GLN B NE2 1 ATOM 3706 N N . LEU B 1 54 ? -48.151 52.784 5.115 1.00 18.33 ? 87 LEU B N 1 ATOM 3707 C CA . LEU B 1 54 ? -48.127 52.396 6.525 1.00 18.12 ? 87 LEU B CA 1 ATOM 3708 C C . LEU B 1 54 ? -47.459 51.042 6.681 1.00 18.30 ? 87 LEU B C 1 ATOM 3709 O O . LEU B 1 54 ? -46.517 50.892 7.489 1.00 19.14 ? 87 LEU B O 1 ATOM 3710 C CB . LEU B 1 54 ? -49.539 52.351 7.184 1.00 17.38 ? 87 LEU B CB 1 ATOM 3711 C CG . LEU B 1 54 ? -49.579 51.775 8.596 1.00 15.74 ? 87 LEU B CG 1 ATOM 3712 C CD1 . LEU B 1 54 ? -48.673 52.618 9.501 1.00 15.15 ? 87 LEU B CD1 1 ATOM 3713 C CD2 . LEU B 1 54 ? -51.017 51.716 9.087 1.00 15.57 ? 87 LEU B CD2 1 ATOM 3714 N N . ILE B 1 55 ? -47.944 50.072 5.935 1.00 16.56 ? 88 ILE B N 1 ATOM 3715 C CA . ILE B 1 55 ? -47.357 48.762 6.008 1.00 17.97 ? 88 ILE B CA 1 ATOM 3716 C C . ILE B 1 55 ? -45.923 48.722 5.632 1.00 16.86 ? 88 ILE B C 1 ATOM 3717 O O . ILE B 1 55 ? -45.153 47.958 6.174 1.00 15.48 ? 88 ILE B O 1 ATOM 3718 C CB . ILE B 1 55 ? -48.098 47.817 5.104 1.00 19.47 ? 88 ILE B CB 1 ATOM 3719 C CG1 . ILE B 1 55 ? -49.467 47.550 5.740 1.00 20.91 ? 88 ILE B CG1 1 ATOM 3720 C CG2 . ILE B 1 55 ? -47.343 46.521 4.897 1.00 19.46 ? 88 ILE B CG2 1 ATOM 3721 C CD1 . ILE B 1 55 ? -50.525 47.199 4.700 1.00 21.75 ? 88 ILE B CD1 1 ATOM 3722 N N . LEU B 1 56 ? -45.582 49.534 4.667 1.00 19.11 ? 89 LEU B N 1 ATOM 3723 C CA . LEU B 1 56 ? -44.186 49.578 4.130 1.00 22.32 ? 89 LEU B CA 1 ATOM 3724 C C . LEU B 1 56 ? -43.213 50.125 5.191 1.00 20.22 ? 89 LEU B C 1 ATOM 3725 O O . LEU B 1 56 ? -42.093 49.618 5.349 1.00 19.19 ? 89 LEU B O 1 ATOM 3726 C CB . LEU B 1 56 ? -44.134 50.412 2.835 1.00 23.32 ? 89 LEU B CB 1 ATOM 3727 C CG . LEU B 1 56 ? -42.985 50.293 1.827 1.00 26.55 ? 89 LEU B CG 1 ATOM 3728 C CD1 . LEU B 1 56 ? -42.483 48.861 1.660 1.00 28.10 ? 89 LEU B CD1 1 ATOM 3729 C CD2 . LEU B 1 56 ? -43.450 50.874 0.479 1.00 25.54 ? 89 LEU B CD2 1 ATOM 3730 N N . SER B 1 57 ? -43.707 51.126 5.928 1.00 18.68 ? 90 SER B N 1 ATOM 3731 C CA . SER B 1 57 ? -42.956 51.811 6.948 1.00 17.56 ? 90 SER B CA 1 ATOM 3732 C C . SER B 1 57 ? -42.758 50.918 8.161 1.00 17.03 ? 90 SER B C 1 ATOM 3733 O O . SER B 1 57 ? -41.739 50.969 8.849 1.00 17.72 ? 90 SER B O 1 ATOM 3734 C CB . SER B 1 57 ? -43.681 53.079 7.374 1.00 18.02 ? 90 SER B CB 1 ATOM 3735 O OG . SER B 1 57 ? -44.668 52.793 8.350 1.00 18.17 ? 90 SER B OG 1 ATOM 3736 N N . ALA B 1 58 ? -43.743 50.117 8.460 1.00 16.33 ? 91 ALA B N 1 ATOM 3737 C CA . ALA B 1 58 ? -43.533 49.198 9.501 1.00 17.10 ? 91 ALA B CA 1 ATOM 3738 C C . ALA B 1 58 ? -42.409 48.190 9.081 1.00 17.15 ? 91 ALA B C 1 ATOM 3739 O O . ALA B 1 58 ? -41.553 47.829 9.887 1.00 15.46 ? 91 ALA B O 1 ATOM 3740 C CB . ALA B 1 58 ? -44.828 48.500 9.849 1.00 17.07 ? 91 ALA B CB 1 ATOM 3741 N N . PHE B 1 59 ? -42.407 47.735 7.835 1.00 18.51 ? 92 PHE B N 1 ATOM 3742 C CA . PHE B 1 59 ? -41.417 46.705 7.434 1.00 20.62 ? 92 PHE B CA 1 ATOM 3743 C C . PHE B 1 59 ? -40.003 47.338 7.306 1.00 20.66 ? 92 PHE B C 1 ATOM 3744 O O . PHE B 1 59 ? -38.975 46.708 7.608 1.00 17.19 ? 92 PHE B O 1 ATOM 3745 C CB . PHE B 1 59 ? -41.877 45.950 6.163 1.00 20.83 ? 92 PHE B CB 1 ATOM 3746 C CG . PHE B 1 59 ? -42.940 44.884 6.426 1.00 20.99 ? 92 PHE B CG 1 ATOM 3747 C CD1 . PHE B 1 59 ? -42.707 43.852 7.308 1.00 21.83 ? 92 PHE B CD1 1 ATOM 3748 C CD2 . PHE B 1 59 ? -44.128 44.879 5.719 1.00 21.60 ? 92 PHE B CD2 1 ATOM 3749 C CE1 . PHE B 1 59 ? -43.648 42.875 7.509 1.00 21.73 ? 92 PHE B CE1 1 ATOM 3750 C CE2 . PHE B 1 59 ? -45.059 43.897 5.916 1.00 20.09 ? 92 PHE B CE2 1 ATOM 3751 C CZ . PHE B 1 59 ? -44.817 42.908 6.808 1.00 20.41 ? 92 PHE B CZ 1 ATOM 3752 N N . ASP B 1 60 ? -40.033 48.629 6.937 1.00 23.36 ? 93 ASP B N 1 ATOM 3753 C CA . ASP B 1 60 ? -38.871 49.515 6.858 1.00 24.66 ? 93 ASP B CA 1 ATOM 3754 C C . ASP B 1 60 ? -38.231 49.792 8.227 1.00 23.72 ? 93 ASP B C 1 ATOM 3755 O O . ASP B 1 60 ? -36.998 49.699 8.372 1.00 23.19 ? 93 ASP B O 1 ATOM 3756 C CB . ASP B 1 60 ? -39.257 50.835 6.204 1.00 24.54 ? 93 ASP B CB 1 ATOM 3757 C CG . ASP B 1 60 ? -38.071 51.701 5.975 1.00 28.64 ? 93 ASP B CG 1 ATOM 3758 O OD1 . ASP B 1 60 ? -37.201 51.327 5.169 1.00 35.31 ? 93 ASP B OD1 1 ATOM 3759 O OD2 . ASP B 1 60 ? -37.966 52.754 6.605 1.00 33.14 -1 93 ASP B OD2 1 ATOM 3760 N N . PHE B 1 61 ? -39.060 50.141 9.220 1.00 21.63 ? 94 PHE B N 1 ATOM 3761 C CA . PHE B 1 61 ? -38.573 50.201 10.598 1.00 20.54 ? 94 PHE B CA 1 ATOM 3762 C C . PHE B 1 61 ? -37.909 48.841 10.969 1.00 20.69 ? 94 PHE B C 1 ATOM 3763 O O . PHE B 1 61 ? -36.775 48.810 11.453 1.00 19.93 ? 94 PHE B O 1 ATOM 3764 C CB . PHE B 1 61 ? -39.677 50.581 11.606 1.00 19.30 ? 94 PHE B CB 1 ATOM 3765 C CG . PHE B 1 61 ? -39.285 50.302 12.999 1.00 17.44 ? 94 PHE B CG 1 ATOM 3766 C CD1 . PHE B 1 61 ? -38.350 51.090 13.619 1.00 17.97 ? 94 PHE B CD1 1 ATOM 3767 C CD2 . PHE B 1 61 ? -39.710 49.161 13.622 1.00 16.53 ? 94 PHE B CD2 1 ATOM 3768 C CE1 . PHE B 1 61 ? -37.908 50.777 14.911 1.00 17.33 ? 94 PHE B CE1 1 ATOM 3769 C CE2 . PHE B 1 61 ? -39.282 48.854 14.871 1.00 17.44 ? 94 PHE B CE2 1 ATOM 3770 C CZ . PHE B 1 61 ? -38.402 49.696 15.550 1.00 16.39 ? 94 PHE B CZ 1 ATOM 3771 N N . ILE B 1 62 ? -38.572 47.727 10.717 1.00 20.34 ? 95 ILE B N 1 ATOM 3772 C CA . ILE B 1 62 ? -37.921 46.452 10.958 1.00 24.57 ? 95 ILE B CA 1 ATOM 3773 C C . ILE B 1 62 ? -36.460 46.413 10.420 1.00 26.35 ? 95 ILE B C 1 ATOM 3774 O O . ILE B 1 62 ? -35.513 46.272 11.202 1.00 22.17 ? 95 ILE B O 1 ATOM 3775 C CB . ILE B 1 62 ? -38.773 45.278 10.447 1.00 25.78 ? 95 ILE B CB 1 ATOM 3776 C CG1 . ILE B 1 62 ? -39.914 45.073 11.451 1.00 28.51 ? 95 ILE B CG1 1 ATOM 3777 C CG2 . ILE B 1 62 ? -37.928 43.998 10.291 1.00 25.30 ? 95 ILE B CG2 1 ATOM 3778 C CD1 . ILE B 1 62 ? -40.954 44.061 11.016 1.00 30.99 ? 95 ILE B CD1 1 ATOM 3779 N N . LYS B 1 63 ? -36.338 46.578 9.100 1.00 28.97 ? 96 LYS B N 1 ATOM 3780 C CA . LYS B 1 63 ? -35.082 46.671 8.372 1.00 31.10 ? 96 LYS B CA 1 ATOM 3781 C C . LYS B 1 63 ? -34.059 47.544 9.022 1.00 29.94 ? 96 LYS B C 1 ATOM 3782 O O . LYS B 1 63 ? -32.889 47.241 8.977 1.00 30.07 ? 96 LYS B O 1 ATOM 3783 C CB . LYS B 1 63 ? -35.336 47.304 7.008 1.00 36.43 ? 96 LYS B CB 1 ATOM 3784 C CG . LYS B 1 63 ? -35.322 46.363 5.828 1.00 40.60 ? 96 LYS B CG 1 ATOM 3785 C CD . LYS B 1 63 ? -35.229 47.235 4.563 1.00 47.13 ? 96 LYS B CD 1 ATOM 3786 C CE . LYS B 1 63 ? -35.155 46.425 3.274 1.00 52.40 ? 96 LYS B CE 1 ATOM 3787 N NZ . LYS B 1 63 ? -34.194 45.277 3.387 1.00 55.42 1 96 LYS B NZ 1 ATOM 3788 N N . ASN B 1 64 ? -34.501 48.673 9.553 1.00 32.82 ? 97 ASN B N 1 ATOM 3789 C CA . ASN B 1 64 ? -33.620 49.677 10.151 1.00 33.49 ? 97 ASN B CA 1 ATOM 3790 C C . ASN B 1 64 ? -33.663 49.746 11.677 1.00 34.69 ? 97 ASN B C 1 ATOM 3791 O O . ASN B 1 64 ? -33.047 50.612 12.247 1.00 39.23 ? 97 ASN B O 1 ATOM 3792 C CB . ASN B 1 64 ? -33.952 51.050 9.537 1.00 33.07 ? 97 ASN B CB 1 ATOM 3793 C CG . ASN B 1 64 ? -33.672 51.079 8.049 1.00 33.19 ? 97 ASN B CG 1 ATOM 3794 O OD1 . ASN B 1 64 ? -32.563 51.344 7.648 1.00 37.39 ? 97 ASN B OD1 1 ATOM 3795 N ND2 . ASN B 1 64 ? -34.639 50.703 7.239 1.00 33.79 ? 97 ASN B ND2 1 ATOM 3796 N N . SER B 1 65 ? -34.370 48.834 12.347 1.00 35.34 ? 98 SER B N 1 ATOM 3797 C CA . SER B 1 65 ? -34.478 48.871 13.829 1.00 34.28 ? 98 SER B CA 1 ATOM 3798 C C . SER B 1 65 ? -33.164 48.536 14.507 1.00 36.79 ? 98 SER B C 1 ATOM 3799 O O . SER B 1 65 ? -33.071 48.654 15.719 1.00 35.13 ? 98 SER B O 1 ATOM 3800 C CB . SER B 1 65 ? -35.473 47.831 14.333 1.00 30.27 ? 98 SER B CB 1 ATOM 3801 O OG . SER B 1 65 ? -35.095 46.559 13.872 1.00 24.97 ? 98 SER B OG 1 ATOM 3802 N N . GLY B 1 66 ? -32.198 48.046 13.721 1.00 36.44 ? 99 GLY B N 1 ATOM 3803 C CA . GLY B 1 66 ? -30.983 47.510 14.252 1.00 36.08 ? 99 GLY B CA 1 ATOM 3804 C C . GLY B 1 66 ? -31.215 46.274 15.095 1.00 36.33 ? 99 GLY B C 1 ATOM 3805 O O . GLY B 1 66 ? -30.409 45.962 15.948 1.00 44.55 ? 99 GLY B O 1 ATOM 3806 N N . GLN B 1 67 ? -32.304 45.555 14.871 1.00 31.15 ? 100 GLN B N 1 ATOM 3807 C CA . GLN B 1 67 ? -32.547 44.355 15.629 1.00 28.27 ? 100 GLN B CA 1 ATOM 3808 C C . GLN B 1 67 ? -32.384 43.169 14.698 1.00 28.32 ? 100 GLN B C 1 ATOM 3809 O O . GLN B 1 67 ? -32.860 43.173 13.572 1.00 28.22 ? 100 GLN B O 1 ATOM 3810 C CB . GLN B 1 67 ? -33.919 44.396 16.256 1.00 28.21 ? 100 GLN B CB 1 ATOM 3811 C CG . GLN B 1 67 ? -34.078 45.525 17.289 1.00 30.07 ? 100 GLN B CG 1 ATOM 3812 C CD . GLN B 1 67 ? -33.662 45.112 18.697 1.00 31.20 ? 100 GLN B CD 1 ATOM 3813 O OE1 . GLN B 1 67 ? -32.825 44.224 18.890 1.00 30.37 ? 100 GLN B OE1 1 ATOM 3814 N NE2 . GLN B 1 67 ? -34.284 45.739 19.700 1.00 33.75 ? 100 GLN B NE2 1 ATOM 3815 N N . GLU B 1 68 ? -31.649 42.177 15.165 1.00 29.84 ? 101 GLU B N 1 ATOM 3816 C CA . GLU B 1 68 ? -31.336 40.976 14.418 1.00 30.76 ? 101 GLU B CA 1 ATOM 3817 C C . GLU B 1 68 ? -32.474 39.957 14.671 1.00 28.08 ? 101 GLU B C 1 ATOM 3818 O O . GLU B 1 68 ? -32.986 39.876 15.794 1.00 30.27 ? 101 GLU B O 1 ATOM 3819 C CB . GLU B 1 68 ? -29.924 40.474 14.837 1.00 35.11 ? 101 GLU B CB 1 ATOM 3820 C CG . GLU B 1 68 ? -29.741 39.903 16.275 1.00 43.35 ? 101 GLU B CG 1 ATOM 3821 C CD . GLU B 1 68 ? -29.437 40.930 17.429 1.00 49.45 ? 101 GLU B CD 1 ATOM 3822 O OE1 . GLU B 1 68 ? -29.586 42.188 17.275 1.00 42.67 ? 101 GLU B OE1 1 ATOM 3823 O OE2 . GLU B 1 68 ? -29.069 40.450 18.549 1.00 53.80 -1 101 GLU B OE2 1 ATOM 3824 N N . ALA B 1 69 ? -32.930 39.244 13.644 1.00 24.57 ? 102 ALA B N 1 ATOM 3825 C CA . ALA B 1 69 ? -33.886 38.150 13.878 1.00 24.37 ? 102 ALA B CA 1 ATOM 3826 C C . ALA B 1 69 ? -33.708 36.879 13.028 1.00 24.12 ? 102 ALA B C 1 ATOM 3827 O O . ALA B 1 69 ? -33.367 36.877 11.838 1.00 24.13 ? 102 ALA B O 1 ATOM 3828 C CB . ALA B 1 69 ? -35.348 38.625 13.822 1.00 23.01 ? 102 ALA B CB 1 ATOM 3829 N N . SER B 1 70 ? -33.994 35.797 13.708 1.00 24.13 ? 103 SER B N 1 ATOM 3830 C CA . SER B 1 70 ? -33.946 34.474 13.167 1.00 25.34 ? 103 SER B CA 1 ATOM 3831 C C . SER B 1 70 ? -35.214 34.151 12.420 1.00 22.76 ? 103 SER B C 1 ATOM 3832 O O . SER B 1 70 ? -35.187 33.246 11.562 1.00 25.19 ? 103 SER B O 1 ATOM 3833 C CB . SER B 1 70 ? -33.788 33.473 14.330 1.00 26.25 ? 103 SER B CB 1 ATOM 3834 O OG . SER B 1 70 ? -32.709 33.923 15.140 1.00 30.88 ? 103 SER B OG 1 ATOM 3835 N N . PHE B 1 71 ? -36.327 34.783 12.773 1.00 18.48 ? 104 PHE B N 1 ATOM 3836 C CA . PHE B 1 71 ? -37.496 34.576 11.966 1.00 18.58 ? 104 PHE B CA 1 ATOM 3837 C C . PHE B 1 71 ? -38.624 35.537 12.234 1.00 17.91 ? 104 PHE B C 1 ATOM 3838 O O . PHE B 1 71 ? -38.490 36.436 13.019 1.00 17.56 ? 104 PHE B O 1 ATOM 3839 C CB . PHE B 1 71 ? -37.995 33.110 12.057 1.00 19.66 ? 104 PHE B CB 1 ATOM 3840 C CG . PHE B 1 71 ? -38.421 32.701 13.421 1.00 19.77 ? 104 PHE B CG 1 ATOM 3841 C CD1 . PHE B 1 71 ? -37.528 32.098 14.258 1.00 18.03 ? 104 PHE B CD1 1 ATOM 3842 C CD2 . PHE B 1 71 ? -39.747 32.951 13.852 1.00 19.57 ? 104 PHE B CD2 1 ATOM 3843 C CE1 . PHE B 1 71 ? -37.935 31.689 15.484 1.00 20.29 ? 104 PHE B CE1 1 ATOM 3844 C CE2 . PHE B 1 71 ? -40.147 32.595 15.099 1.00 20.14 ? 104 PHE B CE2 1 ATOM 3845 C CZ . PHE B 1 71 ? -39.246 31.961 15.934 1.00 21.03 ? 104 PHE B CZ 1 ATOM 3846 N N . MET B 1 72 ? -39.723 35.366 11.506 1.00 19.69 ? 105 MET B N 1 ATOM 3847 C CA . MET B 1 72 ? -40.920 36.218 11.649 1.00 20.51 ? 105 MET B CA 1 ATOM 3848 C C . MET B 1 72 ? -42.166 35.375 11.620 1.00 18.44 ? 105 MET B C 1 ATOM 3849 O O . MET B 1 72 ? -42.322 34.437 10.788 1.00 15.94 ? 105 MET B O 1 ATOM 3850 C CB . MET B 1 72 ? -41.035 37.306 10.545 1.00 21.35 ? 105 MET B CB 1 ATOM 3851 C CG . MET B 1 72 ? -42.082 38.418 10.818 1.00 22.98 ? 105 MET B CG 1 ATOM 3852 S SD . MET B 1 72 ? -42.301 39.715 9.553 1.00 24.88 ? 105 MET B SD 1 ATOM 3853 C CE . MET B 1 72 ? -40.626 40.131 9.101 1.00 24.82 ? 105 MET B CE 1 ATOM 3854 N N . ILE B 1 73 ? -43.025 35.742 12.559 1.00 17.11 ? 106 ILE B N 1 ATOM 3855 C CA A ILE B 1 73 ? -44.376 35.243 12.671 0.50 18.47 ? 106 ILE B CA 1 ATOM 3856 C CA B ILE B 1 73 ? -44.378 35.207 12.553 0.50 17.33 ? 106 ILE B CA 1 ATOM 3857 C C . ILE B 1 73 ? -45.417 36.274 12.109 1.00 17.69 ? 106 ILE B C 1 ATOM 3858 O O . ILE B 1 73 ? -45.364 37.439 12.484 1.00 16.52 ? 106 ILE B O 1 ATOM 3859 C CB A ILE B 1 73 ? -44.640 34.987 14.161 0.50 20.06 ? 106 ILE B CB 1 ATOM 3860 C CB B ILE B 1 73 ? -44.743 34.478 13.863 0.50 17.26 ? 106 ILE B CB 1 ATOM 3861 C CG1 A ILE B 1 73 ? -43.588 34.013 14.744 0.50 21.21 ? 106 ILE B CG1 1 ATOM 3862 C CG1 B ILE B 1 73 ? -44.772 35.444 15.072 0.50 16.61 ? 106 ILE B CG1 1 ATOM 3863 C CG2 A ILE B 1 73 ? -46.061 34.513 14.364 0.50 20.85 ? 106 ILE B CG2 1 ATOM 3864 C CG2 B ILE B 1 73 ? -43.779 33.308 14.063 0.50 17.79 ? 106 ILE B CG2 1 ATOM 3865 C CD1 A ILE B 1 73 ? -43.417 32.730 13.960 0.50 20.98 ? 106 ILE B CD1 1 ATOM 3866 C CD1 B ILE B 1 73 ? -45.591 34.923 16.243 0.50 16.11 ? 106 ILE B CD1 1 ATOM 3867 N N . TRP B 1 74 ? -46.351 35.841 11.249 1.00 16.93 ? 107 TRP B N 1 ATOM 3868 C CA . TRP B 1 74 ? -47.219 36.717 10.492 1.00 19.13 ? 107 TRP B CA 1 ATOM 3869 C C . TRP B 1 74 ? -48.595 36.111 10.537 1.00 20.17 ? 107 TRP B C 1 ATOM 3870 O O . TRP B 1 74 ? -48.940 35.203 9.742 1.00 20.31 ? 107 TRP B O 1 ATOM 3871 C CB . TRP B 1 74 ? -46.705 36.841 9.029 1.00 21.13 ? 107 TRP B CB 1 ATOM 3872 C CG . TRP B 1 74 ? -47.637 37.563 8.049 1.00 22.76 ? 107 TRP B CG 1 ATOM 3873 C CD1 . TRP B 1 74 ? -48.579 38.500 8.367 1.00 24.95 ? 107 TRP B CD1 1 ATOM 3874 C CD2 . TRP B 1 74 ? -47.696 37.428 6.650 1.00 22.02 ? 107 TRP B CD2 1 ATOM 3875 N NE1 . TRP B 1 74 ? -49.251 38.917 7.273 1.00 21.52 ? 107 TRP B NE1 1 ATOM 3876 C CE2 . TRP B 1 74 ? -48.748 38.279 6.188 1.00 22.77 ? 107 TRP B CE2 1 ATOM 3877 C CE3 . TRP B 1 74 ? -47.006 36.663 5.733 1.00 22.72 ? 107 TRP B CE3 1 ATOM 3878 C CZ2 . TRP B 1 74 ? -49.094 38.430 4.816 1.00 22.53 ? 107 TRP B CZ2 1 ATOM 3879 C CZ3 . TRP B 1 74 ? -47.382 36.782 4.347 1.00 23.28 ? 107 TRP B CZ3 1 ATOM 3880 C CH2 . TRP B 1 74 ? -48.417 37.678 3.927 1.00 23.09 ? 107 TRP B CH2 1 ATOM 3881 N N . THR B 1 75 ? -49.398 36.561 11.497 1.00 20.21 ? 108 THR B N 1 ATOM 3882 C CA . THR B 1 75 ? -50.669 35.827 11.780 1.00 18.77 ? 108 THR B CA 1 ATOM 3883 C C . THR B 1 75 ? -51.953 36.338 10.988 1.00 18.50 ? 108 THR B C 1 ATOM 3884 O O . THR B 1 75 ? -53.052 36.437 11.553 1.00 17.20 ? 108 THR B O 1 ATOM 3885 C CB . THR B 1 75 ? -50.895 35.635 13.316 1.00 17.12 ? 108 THR B CB 1 ATOM 3886 O OG1 . THR B 1 75 ? -50.832 36.874 14.003 1.00 16.38 ? 108 THR B OG1 1 ATOM 3887 C CG2 . THR B 1 75 ? -49.812 34.792 13.887 1.00 17.97 ? 108 THR B CG2 1 ATOM 3888 N N . GLY B 1 76 ? -51.763 36.651 9.699 1.00 17.68 ? 109 GLY B N 1 ATOM 3889 C CA . GLY B 1 76 ? -52.858 36.843 8.723 1.00 18.29 ? 109 GLY B CA 1 ATOM 3890 C C . GLY B 1 76 ? -53.599 38.169 8.734 1.00 18.16 ? 109 GLY B C 1 ATOM 3891 O O . GLY B 1 76 ? -53.222 39.165 9.448 1.00 19.77 ? 109 GLY B O 1 ATOM 3892 N N . ASP B 1 77 ? -54.713 38.146 8.018 1.00 16.73 ? 110 ASP B N 1 ATOM 3893 C CA . ASP B 1 77 ? -55.610 39.346 7.796 1.00 16.40 ? 110 ASP B CA 1 ATOM 3894 C C . ASP B 1 77 ? -55.186 40.513 6.845 1.00 14.56 ? 110 ASP B C 1 ATOM 3895 O O . ASP B 1 77 ? -55.278 41.707 7.185 1.00 12.73 ? 110 ASP B O 1 ATOM 3896 C CB . ASP B 1 77 ? -56.156 39.911 9.143 1.00 16.67 ? 110 ASP B CB 1 ATOM 3897 C CG . ASP B 1 77 ? -57.528 39.388 9.484 1.00 16.63 ? 110 ASP B CG 1 ATOM 3898 O OD1 . ASP B 1 77 ? -57.983 38.314 9.058 1.00 16.92 ? 110 ASP B OD1 1 ATOM 3899 O OD2 . ASP B 1 77 ? -58.186 40.072 10.219 1.00 19.75 -1 110 ASP B OD2 1 ATOM 3900 N N . SER B 1 78 ? -54.724 40.131 5.656 1.00 13.46 ? 111 SER B N 1 ATOM 3901 C CA . SER B 1 78 ? -54.328 41.108 4.647 1.00 13.19 ? 111 SER B CA 1 ATOM 3902 C C . SER B 1 78 ? -55.403 41.959 3.947 1.00 13.43 ? 111 SER B C 1 ATOM 3903 O O . SER B 1 78 ? -55.215 43.190 3.959 1.00 13.12 ? 111 SER B O 1 ATOM 3904 C CB . SER B 1 78 ? -53.365 40.439 3.695 1.00 13.55 ? 111 SER B CB 1 ATOM 3905 O OG . SER B 1 78 ? -52.369 39.827 4.541 1.00 14.65 ? 111 SER B OG 1 ATOM 3906 N N . PRO B 1 79 ? -56.525 41.361 3.385 1.00 13.11 ? 112 PRO B N 1 ATOM 3907 C CA . PRO B 1 79 ? -57.540 42.234 2.750 1.00 14.56 ? 112 PRO B CA 1 ATOM 3908 C C . PRO B 1 79 ? -58.208 43.290 3.721 1.00 16.09 ? 112 PRO B C 1 ATOM 3909 O O . PRO B 1 79 ? -58.185 43.097 4.955 1.00 15.59 ? 112 PRO B O 1 ATOM 3910 C CB . PRO B 1 79 ? -58.610 41.222 2.236 1.00 14.17 ? 112 PRO B CB 1 ATOM 3911 C CG . PRO B 1 79 ? -57.968 39.898 2.324 1.00 13.20 ? 112 PRO B CG 1 ATOM 3912 C CD . PRO B 1 79 ? -57.071 40.000 3.506 1.00 12.87 ? 112 PRO B CD 1 ATOM 3913 N N . PRO B 1 80 ? -58.788 44.391 3.177 1.00 17.68 ? 113 PRO B N 1 ATOM 3914 C CA . PRO B 1 80 ? -59.423 45.440 4.022 1.00 18.18 ? 113 PRO B CA 1 ATOM 3915 C C . PRO B 1 80 ? -60.821 45.093 4.549 1.00 19.51 ? 113 PRO B C 1 ATOM 3916 O O . PRO B 1 80 ? -61.454 44.086 4.158 1.00 21.17 ? 113 PRO B O 1 ATOM 3917 C CB . PRO B 1 80 ? -59.520 46.651 3.079 1.00 18.01 ? 113 PRO B CB 1 ATOM 3918 C CG . PRO B 1 80 ? -59.522 46.085 1.702 1.00 18.54 ? 113 PRO B CG 1 ATOM 3919 C CD . PRO B 1 80 ? -58.899 44.697 1.731 1.00 18.95 ? 113 PRO B CD 1 ATOM 3920 N N . HIS B 1 81 ? -61.334 45.907 5.444 1.00 20.02 ? 114 HIS B N 1 ATOM 3921 C CA . HIS B 1 81 ? -62.672 45.623 5.951 1.00 20.82 ? 114 HIS B CA 1 ATOM 3922 C C . HIS B 1 81 ? -63.594 46.375 4.968 1.00 23.41 ? 114 HIS B C 1 ATOM 3923 O O . HIS B 1 81 ? -63.932 47.574 5.144 1.00 22.62 ? 114 HIS B O 1 ATOM 3924 C CB . HIS B 1 81 ? -62.871 46.066 7.420 1.00 19.75 ? 114 HIS B CB 1 ATOM 3925 C CG . HIS B 1 81 ? -61.938 45.421 8.403 1.00 19.67 ? 114 HIS B CG 1 ATOM 3926 N ND1 . HIS B 1 81 ? -60.566 45.653 8.411 1.00 19.60 ? 114 HIS B ND1 1 ATOM 3927 C CD2 . HIS B 1 81 ? -62.190 44.619 9.467 1.00 19.18 ? 114 HIS B CD2 1 ATOM 3928 C CE1 . HIS B 1 81 ? -60.015 44.985 9.410 1.00 19.91 ? 114 HIS B CE1 1 ATOM 3929 N NE2 . HIS B 1 81 ? -60.981 44.366 10.078 1.00 20.63 ? 114 HIS B NE2 1 ATOM 3930 N N . VAL B 1 82 ? -63.927 45.674 3.887 1.00 25.58 ? 115 VAL B N 1 ATOM 3931 C CA . VAL B 1 82 ? -64.968 46.123 2.984 1.00 25.81 ? 115 VAL B CA 1 ATOM 3932 C C . VAL B 1 82 ? -66.035 45.055 2.975 1.00 23.37 ? 115 VAL B C 1 ATOM 3933 O O . VAL B 1 82 ? -65.781 43.916 3.340 1.00 20.64 ? 115 VAL B O 1 ATOM 3934 C CB . VAL B 1 82 ? -64.466 46.439 1.561 1.00 26.99 ? 115 VAL B CB 1 ATOM 3935 C CG1 . VAL B 1 82 ? -63.583 47.683 1.521 1.00 26.85 ? 115 VAL B CG1 1 ATOM 3936 C CG2 . VAL B 1 82 ? -63.727 45.254 1.021 1.00 29.38 ? 115 VAL B CG2 1 ATOM 3937 N N . PRO B 1 83 ? -67.246 45.446 2.568 1.00 25.67 ? 116 PRO B N 1 ATOM 3938 C CA . PRO B 1 83 ? -68.346 44.501 2.414 1.00 25.52 ? 116 PRO B CA 1 ATOM 3939 C C . PRO B 1 83 ? -67.995 43.455 1.407 1.00 24.10 ? 116 PRO B C 1 ATOM 3940 O O . PRO B 1 83 ? -67.355 43.762 0.383 1.00 25.50 ? 116 PRO B O 1 ATOM 3941 C CB . PRO B 1 83 ? -69.511 45.372 1.880 1.00 25.59 ? 116 PRO B CB 1 ATOM 3942 C CG . PRO B 1 83 ? -69.074 46.792 1.999 1.00 25.84 ? 116 PRO B CG 1 ATOM 3943 C CD . PRO B 1 83 ? -67.581 46.782 2.023 1.00 26.36 ? 116 PRO B CD 1 ATOM 3944 N N . VAL B 1 84 ? -68.422 42.242 1.692 1.00 24.27 ? 117 VAL B N 1 ATOM 3945 C CA . VAL B 1 84 ? -68.113 41.066 0.865 1.00 28.20 ? 117 VAL B CA 1 ATOM 3946 C C . VAL B 1 84 ? -68.274 41.248 -0.664 1.00 30.18 ? 117 VAL B C 1 ATOM 3947 O O . VAL B 1 84 ? -67.358 40.886 -1.400 1.00 31.84 ? 117 VAL B O 1 ATOM 3948 C CB . VAL B 1 84 ? -68.913 39.805 1.328 1.00 30.22 ? 117 VAL B CB 1 ATOM 3949 C CG1 . VAL B 1 84 ? -68.478 38.554 0.560 1.00 31.37 ? 117 VAL B CG1 1 ATOM 3950 C CG2 . VAL B 1 84 ? -68.722 39.559 2.824 1.00 30.03 ? 117 VAL B CG2 1 ATOM 3951 N N . PRO B 1 85 ? -69.408 41.811 -1.147 1.00 33.42 ? 118 PRO B N 1 ATOM 3952 C CA . PRO B 1 85 ? -69.569 41.931 -2.612 1.00 33.99 ? 118 PRO B CA 1 ATOM 3953 C C . PRO B 1 85 ? -68.559 42.848 -3.297 1.00 34.35 ? 118 PRO B C 1 ATOM 3954 O O . PRO B 1 85 ? -68.337 42.756 -4.504 1.00 33.88 ? 118 PRO B O 1 ATOM 3955 C CB . PRO B 1 85 ? -71.004 42.473 -2.785 1.00 34.74 ? 118 PRO B CB 1 ATOM 3956 C CG . PRO B 1 85 ? -71.690 42.216 -1.480 1.00 37.59 ? 118 PRO B CG 1 ATOM 3957 C CD . PRO B 1 85 ? -70.612 42.284 -0.429 1.00 35.11 ? 118 PRO B CD 1 ATOM 3958 N N . GLU B 1 86 ? -67.943 43.732 -2.539 1.00 35.98 ? 119 GLU B N 1 ATOM 3959 C CA . GLU B 1 86 ? -66.909 44.598 -3.106 1.00 39.21 ? 119 GLU B CA 1 ATOM 3960 C C . GLU B 1 86 ? -65.555 43.834 -3.292 1.00 34.55 ? 119 GLU B C 1 ATOM 3961 O O . GLU B 1 86 ? -64.684 44.255 -4.023 1.00 31.20 ? 119 GLU B O 1 ATOM 3962 C CB . GLU B 1 86 ? -66.770 45.877 -2.239 1.00 41.63 ? 119 GLU B CB 1 ATOM 3963 C CG . GLU B 1 86 ? -66.444 47.117 -3.051 1.00 49.38 ? 119 GLU B CG 1 ATOM 3964 C CD . GLU B 1 86 ? -65.845 48.241 -2.207 1.00 57.74 ? 119 GLU B CD 1 ATOM 3965 O OE1 . GLU B 1 86 ? -64.862 48.922 -2.677 1.00 53.40 ? 119 GLU B OE1 1 ATOM 3966 O OE2 . GLU B 1 86 ? -66.367 48.412 -1.072 1.00 52.08 -1 119 GLU B OE2 1 ATOM 3967 N N . LEU B 1 87 ? -65.392 42.709 -2.621 1.00 33.85 ? 120 LEU B N 1 ATOM 3968 C CA . LEU B 1 87 ? -64.192 41.893 -2.767 1.00 36.65 ? 120 LEU B CA 1 ATOM 3969 C C . LEU B 1 87 ? -64.441 40.634 -3.627 1.00 34.42 ? 120 LEU B C 1 ATOM 3970 O O . LEU B 1 87 ? -65.531 40.431 -4.134 1.00 39.59 ? 120 LEU B O 1 ATOM 3971 C CB . LEU B 1 87 ? -63.661 41.502 -1.371 1.00 37.55 ? 120 LEU B CB 1 ATOM 3972 C CG . LEU B 1 87 ? -62.985 42.639 -0.600 1.00 37.31 ? 120 LEU B CG 1 ATOM 3973 C CD1 . LEU B 1 87 ? -62.557 42.180 0.784 1.00 37.15 ? 120 LEU B CD1 1 ATOM 3974 C CD2 . LEU B 1 87 ? -61.797 43.229 -1.345 1.00 39.14 ? 120 LEU B CD2 1 ATOM 3975 N N . SER B 1 88 ? -63.418 39.809 -3.785 1.00 30.72 ? 121 SER B N 1 ATOM 3976 C CA . SER B 1 88 ? -63.535 38.559 -4.504 1.00 29.54 ? 121 SER B CA 1 ATOM 3977 C C . SER B 1 88 ? -62.318 37.681 -4.189 1.00 29.16 ? 121 SER B C 1 ATOM 3978 O O . SER B 1 88 ? -61.328 38.186 -3.651 1.00 28.52 ? 121 SER B O 1 ATOM 3979 C CB . SER B 1 88 ? -63.563 38.833 -6.003 1.00 27.00 ? 121 SER B CB 1 ATOM 3980 O OG . SER B 1 88 ? -62.240 39.092 -6.427 1.00 26.26 ? 121 SER B OG 1 ATOM 3981 N N . THR B 1 89 ? -62.419 36.380 -4.525 1.00 29.35 ? 122 THR B N 1 ATOM 3982 C CA . THR B 1 89 ? -61.320 35.383 -4.445 1.00 27.66 ? 122 THR B CA 1 ATOM 3983 C C . THR B 1 89 ? -60.028 35.902 -5.115 1.00 28.93 ? 122 THR B C 1 ATOM 3984 O O . THR B 1 89 ? -58.939 35.828 -4.543 1.00 30.38 ? 122 THR B O 1 ATOM 3985 C CB . THR B 1 89 ? -61.800 34.072 -5.072 1.00 27.20 ? 122 THR B CB 1 ATOM 3986 O OG1 . THR B 1 89 ? -62.955 33.672 -4.364 1.00 28.60 ? 122 THR B OG1 1 ATOM 3987 C CG2 . THR B 1 89 ? -60.759 32.891 -5.072 1.00 27.70 ? 122 THR B CG2 1 ATOM 3988 N N . ASP B 1 90 ? -60.162 36.498 -6.287 1.00 30.22 ? 123 ASP B N 1 ATOM 3989 C CA . ASP B 1 90 ? -59.004 36.960 -7.055 1.00 32.78 ? 123 ASP B CA 1 ATOM 3990 C C . ASP B 1 90 ? -58.329 38.141 -6.352 1.00 30.29 ? 123 ASP B C 1 ATOM 3991 O O . ASP B 1 90 ? -57.095 38.201 -6.264 1.00 31.07 ? 123 ASP B O 1 ATOM 3992 C CB . ASP B 1 90 ? -59.430 37.325 -8.504 1.00 36.22 ? 123 ASP B CB 1 ATOM 3993 C CG . ASP B 1 90 ? -58.341 38.080 -9.274 1.00 42.75 ? 123 ASP B CG 1 ATOM 3994 O OD1 . ASP B 1 90 ? -57.219 37.540 -9.472 1.00 47.02 ? 123 ASP B OD1 1 ATOM 3995 O OD2 . ASP B 1 90 ? -58.605 39.244 -9.660 1.00 46.97 -1 123 ASP B OD2 1 ATOM 3996 N N . THR B 1 91 ? -59.148 39.082 -5.881 1.00 28.26 ? 124 THR B N 1 ATOM 3997 C CA . THR B 1 91 ? -58.662 40.255 -5.162 1.00 27.97 ? 124 THR B CA 1 ATOM 3998 C C . THR B 1 91 ? -58.075 39.891 -3.795 1.00 28.58 ? 124 THR B C 1 ATOM 3999 O O . THR B 1 91 ? -57.032 40.409 -3.449 1.00 30.43 ? 124 THR B O 1 ATOM 4000 C CB . THR B 1 91 ? -59.772 41.290 -4.975 1.00 27.15 ? 124 THR B CB 1 ATOM 4001 O OG1 . THR B 1 91 ? -60.325 41.613 -6.259 1.00 28.23 ? 124 THR B OG1 1 ATOM 4002 C CG2 . THR B 1 91 ? -59.212 42.544 -4.298 1.00 26.24 ? 124 THR B CG2 1 ATOM 4003 N N . VAL B 1 92 ? -58.730 38.992 -3.043 1.00 27.35 ? 125 VAL B N 1 ATOM 4004 C CA . VAL B 1 92 ? -58.168 38.475 -1.807 1.00 26.81 ? 125 VAL B CA 1 ATOM 4005 C C . VAL B 1 92 ? -56.773 37.909 -2.058 1.00 25.96 ? 125 VAL B C 1 ATOM 4006 O O . VAL B 1 92 ? -55.826 38.319 -1.370 1.00 26.59 ? 125 VAL B O 1 ATOM 4007 C CB . VAL B 1 92 ? -59.118 37.491 -1.105 1.00 27.55 ? 125 VAL B CB 1 ATOM 4008 C CG1 . VAL B 1 92 ? -58.409 36.701 -0.011 1.00 26.56 ? 125 VAL B CG1 1 ATOM 4009 C CG2 . VAL B 1 92 ? -60.282 38.269 -0.506 1.00 28.95 ? 125 VAL B CG2 1 ATOM 4010 N N . ILE B 1 93 ? -56.634 37.052 -3.081 1.00 24.57 ? 126 ILE B N 1 ATOM 4011 C CA . ILE B 1 93 ? -55.333 36.450 -3.440 1.00 23.24 ? 126 ILE B CA 1 ATOM 4012 C C . ILE B 1 93 ? -54.294 37.501 -3.845 1.00 24.41 ? 126 ILE B C 1 ATOM 4013 O O . ILE B 1 93 ? -53.130 37.432 -3.422 1.00 23.04 ? 126 ILE B O 1 ATOM 4014 C CB . ILE B 1 93 ? -55.491 35.368 -4.527 1.00 23.23 ? 126 ILE B CB 1 ATOM 4015 C CG1 . ILE B 1 93 ? -56.207 34.146 -3.917 1.00 24.55 ? 126 ILE B CG1 1 ATOM 4016 C CG2 . ILE B 1 93 ? -54.133 34.949 -5.092 1.00 22.49 ? 126 ILE B CG2 1 ATOM 4017 C CD1 . ILE B 1 93 ? -56.710 33.120 -4.917 1.00 24.97 ? 126 ILE B CD1 1 ATOM 4018 N N . ASN B 1 94 ? -54.699 38.502 -4.620 1.00 25.79 ? 127 ASN B N 1 ATOM 4019 C CA . ASN B 1 94 ? -53.756 39.553 -4.980 1.00 28.38 ? 127 ASN B CA 1 ATOM 4020 C C . ASN B 1 94 ? -53.258 40.356 -3.813 1.00 27.47 ? 127 ASN B C 1 ATOM 4021 O O . ASN B 1 94 ? -52.114 40.816 -3.815 1.00 26.98 ? 127 ASN B O 1 ATOM 4022 C CB . ASN B 1 94 ? -54.358 40.527 -5.950 1.00 34.46 ? 127 ASN B CB 1 ATOM 4023 C CG . ASN B 1 94 ? -54.555 39.928 -7.328 1.00 39.26 ? 127 ASN B CG 1 ATOM 4024 O OD1 . ASN B 1 94 ? -53.971 38.902 -7.671 1.00 41.57 ? 127 ASN B OD1 1 ATOM 4025 N ND2 . ASN B 1 94 ? -55.417 40.557 -8.112 1.00 42.75 ? 127 ASN B ND2 1 ATOM 4026 N N . VAL B 1 95 ? -54.118 40.558 -2.825 1.00 26.44 ? 128 VAL B N 1 ATOM 4027 C CA . VAL B 1 95 ? -53.709 41.266 -1.630 1.00 24.71 ? 128 VAL B CA 1 ATOM 4028 C C . VAL B 1 95 ? -52.757 40.410 -0.846 1.00 22.42 ? 128 VAL B C 1 ATOM 4029 O O . VAL B 1 95 ? -51.647 40.861 -0.482 1.00 20.25 ? 128 VAL B O 1 ATOM 4030 C CB . VAL B 1 95 ? -54.887 41.648 -0.759 1.00 25.71 ? 128 VAL B CB 1 ATOM 4031 C CG1 . VAL B 1 95 ? -54.380 42.121 0.592 1.00 26.02 ? 128 VAL B CG1 1 ATOM 4032 C CG2 . VAL B 1 95 ? -55.649 42.765 -1.452 1.00 26.22 ? 128 VAL B CG2 1 ATOM 4033 N N . ILE B 1 96 ? -53.154 39.164 -0.625 1.00 21.29 ? 129 ILE B N 1 ATOM 4034 C CA . ILE B 1 96 ? -52.230 38.246 0.050 1.00 22.10 ? 129 ILE B CA 1 ATOM 4035 C C . ILE B 1 96 ? -50.861 38.159 -0.694 1.00 22.84 ? 129 ILE B C 1 ATOM 4036 O O . ILE B 1 96 ? -49.798 38.231 -0.048 1.00 22.90 ? 129 ILE B O 1 ATOM 4037 C CB . ILE B 1 96 ? -52.817 36.843 0.312 1.00 21.78 ? 129 ILE B CB 1 ATOM 4038 C CG1 . ILE B 1 96 ? -54.039 36.905 1.256 1.00 22.49 ? 129 ILE B CG1 1 ATOM 4039 C CG2 . ILE B 1 96 ? -51.730 35.944 0.934 1.00 22.98 ? 129 ILE B CG2 1 ATOM 4040 C CD1 . ILE B 1 96 ? -54.645 35.525 1.584 1.00 20.72 ? 129 ILE B CD1 1 ATOM 4041 N N . THR B 1 97 ? -50.900 38.019 -2.027 1.00 23.61 ? 130 THR B N 1 ATOM 4042 C CA . THR B 1 97 ? -49.681 37.985 -2.868 1.00 24.01 ? 130 THR B CA 1 ATOM 4043 C C . THR B 1 97 ? -48.811 39.218 -2.696 1.00 23.82 ? 130 THR B C 1 ATOM 4044 O O . THR B 1 97 ? -47.581 39.120 -2.559 1.00 23.54 ? 130 THR B O 1 ATOM 4045 C CB . THR B 1 97 ? -50.028 37.862 -4.369 1.00 23.40 ? 130 THR B CB 1 ATOM 4046 O OG1 . THR B 1 97 ? -50.782 36.660 -4.594 1.00 22.35 ? 130 THR B OG1 1 ATOM 4047 C CG2 . THR B 1 97 ? -48.751 37.811 -5.196 1.00 22.69 ? 130 THR B CG2 1 ATOM 4048 N N . ASN B 1 98 ? -49.468 40.374 -2.693 1.00 24.35 ? 131 ASN B N 1 ATOM 4049 C CA . ASN B 1 98 ? -48.793 41.651 -2.465 1.00 25.14 ? 131 ASN B CA 1 ATOM 4050 C C . ASN B 1 98 ? -48.032 41.722 -1.137 1.00 23.45 ? 131 ASN B C 1 ATOM 4051 O O . ASN B 1 98 ? -46.840 42.112 -1.125 1.00 21.77 ? 131 ASN B O 1 ATOM 4052 C CB . ASN B 1 98 ? -49.762 42.835 -2.598 1.00 25.51 ? 131 ASN B CB 1 ATOM 4053 C CG . ASN B 1 98 ? -49.055 44.171 -2.444 1.00 29.28 ? 131 ASN B CG 1 ATOM 4054 O OD1 . ASN B 1 98 ? -48.468 44.468 -1.391 1.00 30.88 ? 131 ASN B OD1 1 ATOM 4055 N ND2 . ASN B 1 98 ? -49.113 44.993 -3.491 1.00 34.55 ? 131 ASN B ND2 1 ATOM 4056 N N . MET B 1 99 ? -48.706 41.370 -0.032 1.00 22.32 ? 132 MET B N 1 ATOM 4057 C CA . MET B 1 99 ? -48.007 41.317 1.292 1.00 21.59 ? 132 MET B CA 1 ATOM 4058 C C . MET B 1 99 ? -46.837 40.320 1.251 1.00 20.72 ? 132 MET B C 1 ATOM 4059 O O . MET B 1 99 ? -45.715 40.630 1.724 1.00 19.46 ? 132 MET B O 1 ATOM 4060 C CB . MET B 1 99 ? -48.968 40.997 2.486 1.00 21.02 ? 132 MET B CB 1 ATOM 4061 C CG . MET B 1 99 ? -50.072 42.027 2.762 1.00 19.42 ? 132 MET B CG 1 ATOM 4062 S SD . MET B 1 99 ? -49.463 43.609 3.354 1.00 19.09 ? 132 MET B SD 1 ATOM 4063 C CE . MET B 1 99 ? -49.258 44.476 1.798 1.00 20.15 ? 132 MET B CE 1 ATOM 4064 N N . THR B 1 100 ? -47.093 39.138 0.695 1.00 21.85 ? 133 THR B N 1 ATOM 4065 C CA . THR B 1 100 ? -46.054 38.074 0.612 1.00 26.33 ? 133 THR B CA 1 ATOM 4066 C C . THR B 1 100 ? -44.837 38.539 -0.186 1.00 26.46 ? 133 THR B C 1 ATOM 4067 O O . THR B 1 100 ? -43.692 38.446 0.268 1.00 24.73 ? 133 THR B O 1 ATOM 4068 C CB . THR B 1 100 ? -46.617 36.743 0.001 1.00 28.23 ? 133 THR B CB 1 ATOM 4069 O OG1 . THR B 1 100 ? -47.651 36.224 0.863 1.00 26.60 ? 133 THR B OG1 1 ATOM 4070 C CG2 . THR B 1 100 ? -45.492 35.642 -0.213 1.00 27.70 ? 133 THR B CG2 1 ATOM 4071 N N . THR B 1 101 ? -45.115 39.092 -1.356 1.00 28.05 ? 134 THR B N 1 ATOM 4072 C CA . THR B 1 101 ? -44.064 39.607 -2.250 1.00 29.17 ? 134 THR B CA 1 ATOM 4073 C C . THR B 1 101 ? -43.288 40.734 -1.591 1.00 25.73 ? 134 THR B C 1 ATOM 4074 O O . THR B 1 101 ? -42.055 40.770 -1.647 1.00 25.22 ? 134 THR B O 1 ATOM 4075 C CB . THR B 1 101 ? -44.690 40.100 -3.583 1.00 31.27 ? 134 THR B CB 1 ATOM 4076 O OG1 . THR B 1 101 ? -45.377 39.006 -4.197 1.00 30.83 ? 134 THR B OG1 1 ATOM 4077 C CG2 . THR B 1 101 ? -43.614 40.629 -4.572 1.00 35.14 ? 134 THR B CG2 1 ATOM 4078 N N . THR B 1 102 ? -44.031 41.650 -0.983 1.00 23.55 ? 135 THR B N 1 ATOM 4079 C CA . THR B 1 102 ? -43.451 42.784 -0.316 1.00 23.52 ? 135 THR B CA 1 ATOM 4080 C C . THR B 1 102 ? -42.481 42.330 0.787 1.00 23.75 ? 135 THR B C 1 ATOM 4081 O O . THR B 1 102 ? -41.360 42.852 0.870 1.00 26.12 ? 135 THR B O 1 ATOM 4082 C CB . THR B 1 102 ? -44.563 43.663 0.280 1.00 24.90 ? 135 THR B CB 1 ATOM 4083 O OG1 . THR B 1 102 ? -45.397 44.189 -0.764 1.00 23.55 ? 135 THR B OG1 1 ATOM 4084 C CG2 . THR B 1 102 ? -43.981 44.777 1.168 1.00 25.06 ? 135 THR B CG2 1 ATOM 4085 N N . ILE B 1 103 ? -42.898 41.356 1.607 1.00 21.43 ? 136 ILE B N 1 ATOM 4086 C CA . ILE B 1 103 ? -42.027 40.819 2.666 1.00 22.60 ? 136 ILE B CA 1 ATOM 4087 C C . ILE B 1 103 ? -40.802 40.013 2.114 1.00 22.10 ? 136 ILE B C 1 ATOM 4088 O O . ILE B 1 103 ? -39.679 40.114 2.644 1.00 18.86 ? 136 ILE B O 1 ATOM 4089 C CB . ILE B 1 103 ? -42.821 39.923 3.681 1.00 22.79 ? 136 ILE B CB 1 ATOM 4090 C CG1 . ILE B 1 103 ? -43.834 40.694 4.530 1.00 21.21 ? 136 ILE B CG1 1 ATOM 4091 C CG2 . ILE B 1 103 ? -41.880 39.172 4.621 1.00 22.95 ? 136 ILE B CG2 1 ATOM 4092 C CD1 . ILE B 1 103 ? -44.915 39.734 5.006 1.00 21.06 ? 136 ILE B CD1 1 ATOM 4093 N N . GLN B 1 104 ? -41.029 39.191 1.081 1.00 23.70 ? 137 GLN B N 1 ATOM 4094 C CA . GLN B 1 104 ? -39.940 38.397 0.487 1.00 24.69 ? 137 GLN B CA 1 ATOM 4095 C C . GLN B 1 104 ? -38.901 39.289 -0.180 1.00 25.21 ? 137 GLN B C 1 ATOM 4096 O O . GLN B 1 104 ? -37.706 38.996 -0.138 1.00 24.17 ? 137 GLN B O 1 ATOM 4097 C CB . GLN B 1 104 ? -40.475 37.373 -0.481 1.00 25.32 ? 137 GLN B CB 1 ATOM 4098 C CG . GLN B 1 104 ? -41.124 36.202 0.241 1.00 27.17 ? 137 GLN B CG 1 ATOM 4099 C CD . GLN B 1 104 ? -41.993 35.343 -0.666 1.00 28.67 ? 137 GLN B CD 1 ATOM 4100 O OE1 . GLN B 1 104 ? -42.164 35.650 -1.842 1.00 28.64 ? 137 GLN B OE1 1 ATOM 4101 N NE2 . GLN B 1 104 ? -42.587 34.282 -0.104 1.00 30.78 ? 137 GLN B NE2 1 ATOM 4102 N N . SER B 1 105 ? -39.362 40.391 -0.760 1.00 27.32 ? 138 SER B N 1 ATOM 4103 C CA . SER B 1 105 ? -38.467 41.441 -1.295 1.00 29.51 ? 138 SER B CA 1 ATOM 4104 C C . SER B 1 105 ? -37.578 42.116 -0.281 1.00 29.98 ? 138 SER B C 1 ATOM 4105 O O . SER B 1 105 ? -36.428 42.403 -0.585 1.00 28.92 ? 138 SER B O 1 ATOM 4106 C CB . SER B 1 105 ? -39.274 42.582 -1.940 1.00 29.43 ? 138 SER B CB 1 ATOM 4107 O OG . SER B 1 105 ? -39.714 42.173 -3.200 1.00 32.21 ? 138 SER B OG 1 ATOM 4108 N N . LEU B 1 106 ? -38.143 42.471 0.878 1.00 31.04 ? 139 LEU B N 1 ATOM 4109 C CA . LEU B 1 106 ? -37.400 43.293 1.836 1.00 30.33 ? 139 LEU B CA 1 ATOM 4110 C C . LEU B 1 106 ? -36.534 42.435 2.737 1.00 28.04 ? 139 LEU B C 1 ATOM 4111 O O . LEU B 1 106 ? -35.625 42.955 3.353 1.00 27.90 ? 139 LEU B O 1 ATOM 4112 C CB . LEU B 1 106 ? -38.334 44.182 2.663 1.00 31.20 ? 139 LEU B CB 1 ATOM 4113 C CG . LEU B 1 106 ? -39.115 45.262 1.878 1.00 33.24 ? 139 LEU B CG 1 ATOM 4114 C CD1 . LEU B 1 106 ? -40.089 45.980 2.808 1.00 34.87 ? 139 LEU B CD1 1 ATOM 4115 C CD2 . LEU B 1 106 ? -38.237 46.308 1.207 1.00 32.58 ? 139 LEU B CD2 1 ATOM 4116 N N . PHE B 1 107 ? -36.832 41.133 2.806 1.00 25.38 ? 140 PHE B N 1 ATOM 4117 C CA . PHE B 1 107 ? -36.212 40.215 3.763 1.00 24.76 ? 140 PHE B CA 1 ATOM 4118 C C . PHE B 1 107 ? -35.889 38.932 3.032 1.00 27.01 ? 140 PHE B C 1 ATOM 4119 O O . PHE B 1 107 ? -36.380 37.862 3.383 1.00 25.84 ? 140 PHE B O 1 ATOM 4120 C CB . PHE B 1 107 ? -37.160 39.903 4.963 1.00 24.17 ? 140 PHE B CB 1 ATOM 4121 C CG . PHE B 1 107 ? -37.639 41.115 5.677 1.00 21.03 ? 140 PHE B CG 1 ATOM 4122 C CD1 . PHE B 1 107 ? -36.754 41.844 6.445 1.00 18.49 ? 140 PHE B CD1 1 ATOM 4123 C CD2 . PHE B 1 107 ? -38.912 41.576 5.483 1.00 19.85 ? 140 PHE B CD2 1 ATOM 4124 C CE1 . PHE B 1 107 ? -37.137 42.955 7.102 1.00 18.10 ? 140 PHE B CE1 1 ATOM 4125 C CE2 . PHE B 1 107 ? -39.300 42.726 6.111 1.00 20.80 ? 140 PHE B CE2 1 ATOM 4126 C CZ . PHE B 1 107 ? -38.413 43.404 6.951 1.00 19.74 ? 140 PHE B CZ 1 ATOM 4127 N N . PRO B 1 108 ? -35.063 39.035 1.984 1.00 32.78 ? 141 PRO B N 1 ATOM 4128 C CA . PRO B 1 108 ? -34.729 37.862 1.151 1.00 33.09 ? 141 PRO B CA 1 ATOM 4129 C C . PRO B 1 108 ? -34.234 36.597 1.915 1.00 31.24 ? 141 PRO B C 1 ATOM 4130 O O . PRO B 1 108 ? -34.444 35.500 1.428 1.00 30.56 ? 141 PRO B O 1 ATOM 4131 C CB . PRO B 1 108 ? -33.627 38.405 0.223 1.00 35.08 ? 141 PRO B CB 1 ATOM 4132 C CG . PRO B 1 108 ? -33.143 39.681 0.870 1.00 34.55 ? 141 PRO B CG 1 ATOM 4133 C CD . PRO B 1 108 ? -34.351 40.250 1.536 1.00 32.87 ? 141 PRO B CD 1 ATOM 4134 N N . ASN B 1 109 ? -33.616 36.759 3.089 1.00 29.67 ? 142 ASN B N 1 ATOM 4135 C CA . ASN B 1 109 ? -33.019 35.649 3.839 1.00 28.64 ? 142 ASN B CA 1 ATOM 4136 C C . ASN B 1 109 ? -33.652 35.334 5.198 1.00 27.59 ? 142 ASN B C 1 ATOM 4137 O O . ASN B 1 109 ? -33.004 34.738 6.074 1.00 26.69 ? 142 ASN B O 1 ATOM 4138 C CB . ASN B 1 109 ? -31.524 35.920 4.059 1.00 29.31 ? 142 ASN B CB 1 ATOM 4139 C CG . ASN B 1 109 ? -30.772 36.107 2.758 1.00 31.76 ? 142 ASN B CG 1 ATOM 4140 O OD1 . ASN B 1 109 ? -29.972 37.030 2.621 1.00 33.69 ? 142 ASN B OD1 1 ATOM 4141 N ND2 . ASN B 1 109 ? -31.058 35.263 1.777 1.00 34.08 ? 142 ASN B ND2 1 ATOM 4142 N N . LEU B 1 110 ? -34.905 35.732 5.373 1.00 25.67 ? 143 LEU B N 1 ATOM 4143 C CA . LEU B 1 110 ? -35.571 35.576 6.643 1.00 24.35 ? 143 LEU B CA 1 ATOM 4144 C C . LEU B 1 110 ? -36.698 34.606 6.458 1.00 20.77 ? 143 LEU B C 1 ATOM 4145 O O . LEU B 1 110 ? -37.584 34.821 5.630 1.00 20.30 ? 143 LEU B O 1 ATOM 4146 C CB . LEU B 1 110 ? -36.134 36.925 7.134 1.00 28.01 ? 143 LEU B CB 1 ATOM 4147 C CG . LEU B 1 110 ? -36.704 37.033 8.585 1.00 28.70 ? 143 LEU B CG 1 ATOM 4148 C CD1 . LEU B 1 110 ? -35.661 37.159 9.675 1.00 27.83 ? 143 LEU B CD1 1 ATOM 4149 C CD2 . LEU B 1 110 ? -37.506 38.297 8.617 1.00 31.66 ? 143 LEU B CD2 1 ATOM 4150 N N . GLN B 1 111 ? -36.685 33.542 7.241 1.00 18.02 ? 144 GLN B N 1 ATOM 4151 C CA . GLN B 1 111 ? -37.818 32.654 7.262 1.00 16.70 ? 144 GLN B CA 1 ATOM 4152 C C . GLN B 1 111 ? -39.018 33.345 7.959 1.00 16.57 ? 144 GLN B C 1 ATOM 4153 O O . GLN B 1 111 ? -38.918 33.906 9.072 1.00 16.36 ? 144 GLN B O 1 ATOM 4154 C CB . GLN B 1 111 ? -37.468 31.322 7.923 1.00 15.97 ? 144 GLN B CB 1 ATOM 4155 C CG . GLN B 1 111 ? -38.539 30.254 7.762 1.00 15.19 ? 144 GLN B CG 1 ATOM 4156 C CD . GLN B 1 111 ? -38.080 29.001 8.395 1.00 15.81 ? 144 GLN B CD 1 ATOM 4157 O OE1 . GLN B 1 111 ? -37.254 29.016 9.299 1.00 16.08 ? 144 GLN B OE1 1 ATOM 4158 N NE2 . GLN B 1 111 ? -38.576 27.893 7.917 1.00 17.75 ? 144 GLN B NE2 1 ATOM 4159 N N . VAL B 1 112 ? -40.155 33.286 7.276 1.00 15.87 ? 145 VAL B N 1 ATOM 4160 C CA . VAL B 1 112 ? -41.369 33.905 7.737 1.00 15.24 ? 145 VAL B CA 1 ATOM 4161 C C . VAL B 1 112 ? -42.378 32.759 7.908 1.00 15.34 ? 145 VAL B C 1 ATOM 4162 O O . VAL B 1 112 ? -42.505 31.966 7.037 1.00 15.13 ? 145 VAL B O 1 ATOM 4163 C CB . VAL B 1 112 ? -41.840 34.981 6.754 1.00 13.62 ? 145 VAL B CB 1 ATOM 4164 C CG1 . VAL B 1 112 ? -43.210 35.487 7.155 1.00 13.96 ? 145 VAL B CG1 1 ATOM 4165 C CG2 . VAL B 1 112 ? -40.834 36.110 6.701 1.00 13.03 ? 145 VAL B CG2 1 ATOM 4166 N N . PHE B 1 113 ? -43.018 32.677 9.065 1.00 16.78 ? 146 PHE B N 1 ATOM 4167 C CA . PHE B 1 113 ? -43.978 31.626 9.334 1.00 17.22 ? 146 PHE B CA 1 ATOM 4168 C C . PHE B 1 113 ? -45.367 32.231 9.304 1.00 18.10 ? 146 PHE B C 1 ATOM 4169 O O . PHE B 1 113 ? -45.709 32.984 10.165 1.00 19.71 ? 146 PHE B O 1 ATOM 4170 C CB . PHE B 1 113 ? -43.693 30.975 10.695 1.00 17.06 ? 146 PHE B CB 1 ATOM 4171 C CG . PHE B 1 113 ? -42.447 30.124 10.727 1.00 16.81 ? 146 PHE B CG 1 ATOM 4172 C CD1 . PHE B 1 113 ? -41.219 30.677 11.019 1.00 15.91 ? 146 PHE B CD1 1 ATOM 4173 C CD2 . PHE B 1 113 ? -42.502 28.769 10.457 1.00 16.88 ? 146 PHE B CD2 1 ATOM 4174 C CE1 . PHE B 1 113 ? -40.112 29.889 11.049 1.00 15.74 ? 146 PHE B CE1 1 ATOM 4175 C CE2 . PHE B 1 113 ? -41.360 28.002 10.500 1.00 16.47 ? 146 PHE B CE2 1 ATOM 4176 C CZ . PHE B 1 113 ? -40.188 28.559 10.804 1.00 15.15 ? 146 PHE B CZ 1 ATOM 4177 N N . PRO B 1 114 ? -46.158 31.935 8.246 1.00 18.17 ? 147 PRO B N 1 ATOM 4178 C CA . PRO B 1 114 ? -47.429 32.662 8.279 1.00 16.31 ? 147 PRO B CA 1 ATOM 4179 C C . PRO B 1 114 ? -48.617 31.895 8.839 1.00 16.46 ? 147 PRO B C 1 ATOM 4180 O O . PRO B 1 114 ? -48.669 30.702 8.868 1.00 16.50 ? 147 PRO B O 1 ATOM 4181 C CB . PRO B 1 114 ? -47.687 32.965 6.779 1.00 17.39 ? 147 PRO B CB 1 ATOM 4182 C CG . PRO B 1 114 ? -46.521 32.421 5.980 1.00 17.87 ? 147 PRO B CG 1 ATOM 4183 C CD . PRO B 1 114 ? -45.948 31.348 6.863 1.00 17.92 ? 147 PRO B CD 1 ATOM 4184 N N . ALA B 1 115 ? -49.608 32.612 9.296 1.00 15.83 ? 148 ALA B N 1 ATOM 4185 C CA . ALA B 1 115 ? -50.851 31.949 9.528 1.00 16.22 ? 148 ALA B CA 1 ATOM 4186 C C . ALA B 1 115 ? -51.978 32.636 8.691 1.00 16.77 ? 148 ALA B C 1 ATOM 4187 O O . ALA B 1 115 ? -51.901 33.859 8.473 1.00 18.15 ? 148 ALA B O 1 ATOM 4188 C CB . ALA B 1 115 ? -51.139 31.951 11.013 1.00 15.96 ? 148 ALA B CB 1 ATOM 4189 N N . LEU B 1 116 ? -52.978 31.884 8.217 1.00 15.72 ? 149 LEU B N 1 ATOM 4190 C CA . LEU B 1 116 ? -54.258 32.470 7.681 1.00 17.13 ? 149 LEU B CA 1 ATOM 4191 C C . LEU B 1 116 ? -55.197 33.134 8.737 1.00 18.55 ? 149 LEU B C 1 ATOM 4192 O O . LEU B 1 116 ? -55.326 32.602 9.869 1.00 19.29 ? 149 LEU B O 1 ATOM 4193 C CB . LEU B 1 116 ? -55.121 31.403 6.981 1.00 17.66 ? 149 LEU B CB 1 ATOM 4194 C CG . LEU B 1 116 ? -54.531 30.666 5.760 1.00 17.00 ? 149 LEU B CG 1 ATOM 4195 C CD1 . LEU B 1 116 ? -55.414 29.493 5.444 1.00 16.21 ? 149 LEU B CD1 1 ATOM 4196 C CD2 . LEU B 1 116 ? -54.481 31.670 4.611 1.00 17.57 ? 149 LEU B CD2 1 ATOM 4197 N N . GLY B 1 117 ? -55.836 34.281 8.384 1.00 18.97 ? 150 GLY B N 1 ATOM 4198 C CA . GLY B 1 117 ? -56.933 34.909 9.235 1.00 17.91 ? 150 GLY B CA 1 ATOM 4199 C C . GLY B 1 117 ? -58.327 34.811 8.609 1.00 16.61 ? 150 GLY B C 1 ATOM 4200 O O . GLY B 1 117 ? -58.486 34.353 7.480 1.00 16.18 ? 150 GLY B O 1 ATOM 4201 N N . ASN B 1 118 ? -59.341 35.273 9.307 1.00 16.30 ? 151 ASN B N 1 ATOM 4202 C CA . ASN B 1 118 ? -60.747 35.128 8.816 1.00 16.20 ? 151 ASN B CA 1 ATOM 4203 C C . ASN B 1 118 ? -61.088 35.900 7.569 1.00 17.15 ? 151 ASN B C 1 ATOM 4204 O O . ASN B 1 118 ? -62.080 35.499 6.887 1.00 16.21 ? 151 ASN B O 1 ATOM 4205 C CB . ASN B 1 118 ? -61.729 35.577 9.868 1.00 16.71 ? 151 ASN B CB 1 ATOM 4206 C CG . ASN B 1 118 ? -61.435 36.980 10.358 1.00 17.97 ? 151 ASN B CG 1 ATOM 4207 O OD1 . ASN B 1 118 ? -60.255 37.360 10.580 1.00 18.57 ? 151 ASN B OD1 1 ATOM 4208 N ND2 . ASN B 1 118 ? -62.480 37.769 10.520 1.00 17.67 ? 151 ASN B ND2 1 ATOM 4209 N N . HIS B 1 119 ? -60.286 36.991 7.308 1.00 17.48 ? 152 HIS B N 1 ATOM 4210 C CA . HIS B 1 119 ? -60.345 37.894 6.130 1.00 17.23 ? 152 HIS B CA 1 ATOM 4211 C C . HIS B 1 119 ? -59.378 37.524 4.983 1.00 19.81 ? 152 HIS B C 1 ATOM 4212 O O . HIS B 1 119 ? -59.346 38.215 3.945 1.00 18.79 ? 152 HIS B O 1 ATOM 4213 C CB . HIS B 1 119 ? -59.999 39.345 6.478 1.00 17.40 ? 152 HIS B CB 1 ATOM 4214 C CG . HIS B 1 119 ? -61.095 40.134 7.140 1.00 20.07 ? 152 HIS B CG 1 ATOM 4215 N ND1 . HIS B 1 119 ? -61.848 41.093 6.466 1.00 21.03 ? 152 HIS B ND1 1 ATOM 4216 C CD2 . HIS B 1 119 ? -61.485 40.206 8.441 1.00 20.47 ? 152 HIS B CD2 1 ATOM 4217 C CE1 . HIS B 1 119 ? -62.694 41.658 7.303 1.00 20.17 ? 152 HIS B CE1 1 ATOM 4218 N NE2 . HIS B 1 119 ? -62.499 41.137 8.507 1.00 21.23 ? 152 HIS B NE2 1 ATOM 4219 N N . ASP B 1 120 ? -58.583 36.463 5.137 1.00 22.23 ? 153 ASP B N 1 ATOM 4220 C CA . ASP B 1 120 ? -57.774 35.937 3.987 1.00 23.34 ? 153 ASP B CA 1 ATOM 4221 C C . ASP B 1 120 ? -58.479 34.790 3.215 1.00 24.32 ? 153 ASP B C 1 ATOM 4222 O O . ASP B 1 120 ? -57.896 33.689 2.951 1.00 20.93 ? 153 ASP B O 1 ATOM 4223 C CB . ASP B 1 120 ? -56.417 35.489 4.478 1.00 22.62 ? 153 ASP B CB 1 ATOM 4224 C CG . ASP B 1 120 ? -55.655 36.602 5.121 1.00 21.34 ? 153 ASP B CG 1 ATOM 4225 O OD1 . ASP B 1 120 ? -55.962 37.804 4.821 1.00 16.03 ? 153 ASP B OD1 1 ATOM 4226 O OD2 . ASP B 1 120 ? -54.795 36.221 5.997 1.00 22.84 -1 153 ASP B OD2 1 ATOM 4227 N N . TYR B 1 121 ? -59.741 35.106 2.879 1.00 23.85 ? 154 TYR B N 1 ATOM 4228 C CA . TYR B 1 121 ? -60.675 34.240 2.170 1.00 24.05 ? 154 TYR B CA 1 ATOM 4229 C C . TYR B 1 121 ? -61.784 35.094 1.645 1.00 23.50 ? 154 TYR B C 1 ATOM 4230 O O . TYR B 1 121 ? -62.097 36.192 2.153 1.00 21.59 ? 154 TYR B O 1 ATOM 4231 C CB . TYR B 1 121 ? -61.323 33.172 3.065 1.00 24.82 ? 154 TYR B CB 1 ATOM 4232 C CG . TYR B 1 121 ? -61.749 31.963 2.253 1.00 25.81 ? 154 TYR B CG 1 ATOM 4233 C CD1 . TYR B 1 121 ? -60.771 31.085 1.722 1.00 23.98 ? 154 TYR B CD1 1 ATOM 4234 C CD2 . TYR B 1 121 ? -63.113 31.700 1.971 1.00 23.99 ? 154 TYR B CD2 1 ATOM 4235 C CE1 . TYR B 1 121 ? -61.135 30.007 0.965 1.00 24.42 ? 154 TYR B CE1 1 ATOM 4236 C CE2 . TYR B 1 121 ? -63.474 30.607 1.218 1.00 22.06 ? 154 TYR B CE2 1 ATOM 4237 C CZ . TYR B 1 121 ? -62.487 29.790 0.690 1.00 23.83 ? 154 TYR B CZ 1 ATOM 4238 O OH . TYR B 1 121 ? -62.798 28.709 -0.102 1.00 24.56 ? 154 TYR B OH 1 ATOM 4239 N N . TRP B 1 122 ? -62.401 34.563 0.619 1.00 26.12 ? 155 TRP B N 1 ATOM 4240 C CA . TRP B 1 122 ? -63.621 35.168 0.069 1.00 28.49 ? 155 TRP B CA 1 ATOM 4241 C C . TRP B 1 122 ? -64.727 34.101 -0.039 1.00 25.81 ? 155 TRP B C 1 ATOM 4242 O O . TRP B 1 122 ? -64.476 33.033 -0.564 1.00 24.90 ? 155 TRP B O 1 ATOM 4243 C CB . TRP B 1 122 ? -63.367 35.862 -1.265 1.00 28.54 ? 155 TRP B CB 1 ATOM 4244 C CG . TRP B 1 122 ? -64.541 36.679 -1.615 1.00 33.99 ? 155 TRP B CG 1 ATOM 4245 C CD1 . TRP B 1 122 ? -64.739 38.009 -1.357 1.00 35.69 ? 155 TRP B CD1 1 ATOM 4246 C CD2 . TRP B 1 122 ? -65.733 36.208 -2.231 1.00 37.10 ? 155 TRP B CD2 1 ATOM 4247 N NE1 . TRP B 1 122 ? -65.978 38.402 -1.804 1.00 33.75 ? 155 TRP B NE1 1 ATOM 4248 C CE2 . TRP B 1 122 ? -66.611 37.317 -2.346 1.00 37.94 ? 155 TRP B CE2 1 ATOM 4249 C CE3 . TRP B 1 122 ? -66.135 34.959 -2.732 1.00 37.06 ? 155 TRP B CE3 1 ATOM 4250 C CZ2 . TRP B 1 122 ? -67.875 37.214 -2.942 1.00 40.78 ? 155 TRP B CZ2 1 ATOM 4251 C CZ3 . TRP B 1 122 ? -67.380 34.843 -3.319 1.00 39.97 ? 155 TRP B CZ3 1 ATOM 4252 C CH2 . TRP B 1 122 ? -68.244 35.971 -3.424 1.00 42.07 ? 155 TRP B CH2 1 ATOM 4253 N N . PRO B 1 123 ? -65.900 34.328 0.559 1.00 24.75 ? 156 PRO B N 1 ATOM 4254 C CA . PRO B 1 123 ? -66.199 35.420 1.508 1.00 24.32 ? 156 PRO B CA 1 ATOM 4255 C C . PRO B 1 123 ? -65.543 35.299 2.913 1.00 23.53 ? 156 PRO B C 1 ATOM 4256 O O . PRO B 1 123 ? -65.336 34.208 3.422 1.00 23.22 ? 156 PRO B O 1 ATOM 4257 C CB . PRO B 1 123 ? -67.707 35.305 1.675 1.00 24.95 ? 156 PRO B CB 1 ATOM 4258 C CG . PRO B 1 123 ? -68.020 33.841 1.455 1.00 25.16 ? 156 PRO B CG 1 ATOM 4259 C CD . PRO B 1 123 ? -66.871 33.228 0.672 1.00 25.34 ? 156 PRO B CD 1 ATOM 4260 N N . GLN B 1 124 ? -65.276 36.434 3.538 1.00 22.91 ? 157 GLN B N 1 ATOM 4261 C CA . GLN B 1 124 ? -64.497 36.456 4.727 1.00 21.37 ? 157 GLN B CA 1 ATOM 4262 C C . GLN B 1 124 ? -65.163 35.477 5.623 1.00 21.98 ? 157 GLN B C 1 ATOM 4263 O O . GLN B 1 124 ? -66.363 35.238 5.485 1.00 21.32 ? 157 GLN B O 1 ATOM 4264 C CB . GLN B 1 124 ? -64.489 37.830 5.344 1.00 20.80 ? 157 GLN B CB 1 ATOM 4265 C CG . GLN B 1 124 ? -65.865 38.326 5.673 1.00 21.50 ? 157 GLN B CG 1 ATOM 4266 C CD . GLN B 1 124 ? -65.825 39.632 6.449 1.00 23.06 ? 157 GLN B CD 1 ATOM 4267 O OE1 . GLN B 1 124 ? -65.948 40.696 5.839 1.00 26.29 ? 157 GLN B OE1 1 ATOM 4268 N NE2 . GLN B 1 124 ? -65.618 39.563 7.795 1.00 21.87 ? 157 GLN B NE2 1 ATOM 4269 N N . ASP B 1 125 ? -64.370 34.851 6.478 1.00 20.15 ? 158 ASP B N 1 ATOM 4270 C CA . ASP B 1 125 ? -64.882 34.024 7.490 1.00 21.16 ? 158 ASP B CA 1 ATOM 4271 C C . ASP B 1 125 ? -65.340 32.633 7.122 1.00 22.04 ? 158 ASP B C 1 ATOM 4272 O O . ASP B 1 125 ? -65.602 31.835 8.037 1.00 23.69 ? 158 ASP B O 1 ATOM 4273 C CB . ASP B 1 125 ? -66.114 34.618 8.174 1.00 21.33 ? 158 ASP B CB 1 ATOM 4274 C CG . ASP B 1 125 ? -65.793 35.831 8.991 1.00 21.42 ? 158 ASP B CG 1 ATOM 4275 O OD1 . ASP B 1 125 ? -64.653 36.256 9.179 1.00 23.90 ? 158 ASP B OD1 1 ATOM 4276 O OD2 . ASP B 1 125 ? -66.735 36.421 9.448 1.00 23.50 -1 158 ASP B OD2 1 ATOM 4277 N N . GLN B 1 126 ? -65.412 32.286 5.844 1.00 22.61 ? 159 GLN B N 1 ATOM 4278 C CA . GLN B 1 126 ? -66.090 31.021 5.470 1.00 23.88 ? 159 GLN B CA 1 ATOM 4279 C C . GLN B 1 126 ? -65.034 30.035 5.049 1.00 24.35 ? 159 GLN B C 1 ATOM 4280 O O . GLN B 1 126 ? -65.019 29.591 3.912 1.00 26.63 ? 159 GLN B O 1 ATOM 4281 C CB . GLN B 1 126 ? -67.168 31.139 4.399 1.00 24.09 ? 159 GLN B CB 1 ATOM 4282 C CG . GLN B 1 126 ? -68.266 32.139 4.740 1.00 24.81 ? 159 GLN B CG 1 ATOM 4283 C CD . GLN B 1 126 ? -68.931 31.872 6.082 1.00 26.12 ? 159 GLN B CD 1 ATOM 4284 O OE1 . GLN B 1 126 ? -69.236 30.711 6.429 1.00 27.34 ? 159 GLN B OE1 1 ATOM 4285 N NE2 . GLN B 1 126 ? -69.124 32.943 6.874 1.00 26.06 ? 159 GLN B NE2 1 ATOM 4286 N N . LEU B 1 127 ? -64.126 29.725 5.978 1.00 25.50 ? 160 LEU B N 1 ATOM 4287 C CA . LEU B 1 127 ? -62.915 29.045 5.638 1.00 25.00 ? 160 LEU B CA 1 ATOM 4288 C C . LEU B 1 127 ? -63.255 27.585 5.587 1.00 25.41 ? 160 LEU B C 1 ATOM 4289 O O . LEU B 1 127 ? -63.868 27.071 6.534 1.00 26.36 ? 160 LEU B O 1 ATOM 4290 C CB . LEU B 1 127 ? -61.795 29.411 6.607 1.00 27.72 ? 160 LEU B CB 1 ATOM 4291 C CG . LEU B 1 127 ? -61.018 30.633 6.012 1.00 31.50 ? 160 LEU B CG 1 ATOM 4292 C CD1 . LEU B 1 127 ? -61.675 31.976 6.384 1.00 30.79 ? 160 LEU B CD1 1 ATOM 4293 C CD2 . LEU B 1 127 ? -59.517 30.668 6.314 1.00 31.05 ? 160 LEU B CD2 1 ATOM 4294 N N . PRO B 1 128 ? -62.984 26.935 4.428 1.00 23.74 ? 161 PRO B N 1 ATOM 4295 C CA . PRO B 1 128 ? -63.317 25.520 4.169 1.00 22.39 ? 161 PRO B CA 1 ATOM 4296 C C . PRO B 1 128 ? -62.416 24.472 4.842 1.00 23.29 ? 161 PRO B C 1 ATOM 4297 O O . PRO B 1 128 ? -61.226 24.723 5.203 1.00 25.50 ? 161 PRO B O 1 ATOM 4298 C CB . PRO B 1 128 ? -63.130 25.412 2.675 1.00 21.58 ? 161 PRO B CB 1 ATOM 4299 C CG . PRO B 1 128 ? -62.082 26.432 2.347 1.00 21.92 ? 161 PRO B CG 1 ATOM 4300 C CD . PRO B 1 128 ? -62.432 27.587 3.224 1.00 22.38 ? 161 PRO B CD 1 ATOM 4301 N N . VAL B 1 129 ? -62.985 23.294 4.953 1.00 22.38 ? 162 VAL B N 1 ATOM 4302 C CA . VAL B 1 129 ? -62.303 22.103 5.467 1.00 24.08 ? 162 VAL B CA 1 ATOM 4303 C C . VAL B 1 129 ? -61.507 21.310 4.393 1.00 23.09 ? 162 VAL B C 1 ATOM 4304 O O . VAL B 1 129 ? -60.686 20.419 4.724 1.00 23.24 ? 162 VAL B O 1 ATOM 4305 C CB . VAL B 1 129 ? -63.357 21.183 6.141 1.00 25.73 ? 162 VAL B CB 1 ATOM 4306 C CG1 . VAL B 1 129 ? -62.960 19.720 6.119 1.00 29.69 ? 162 VAL B CG1 1 ATOM 4307 C CG2 . VAL B 1 129 ? -63.644 21.664 7.560 1.00 24.71 ? 162 VAL B CG2 1 ATOM 4308 N N . VAL B 1 130 ? -61.750 21.616 3.114 1.00 19.78 ? 163 VAL B N 1 ATOM 4309 C CA . VAL B 1 130 ? -61.164 20.838 2.004 1.00 16.94 ? 163 VAL B CA 1 ATOM 4310 C C . VAL B 1 130 ? -60.307 21.793 1.263 1.00 16.13 ? 163 VAL B C 1 ATOM 4311 O O . VAL B 1 130 ? -60.377 22.958 1.569 1.00 15.56 ? 163 VAL B O 1 ATOM 4312 C CB . VAL B 1 130 ? -62.252 20.187 1.131 1.00 14.69 ? 163 VAL B CB 1 ATOM 4313 C CG1 . VAL B 1 130 ? -63.122 19.304 1.994 1.00 13.91 ? 163 VAL B CG1 1 ATOM 4314 C CG2 . VAL B 1 130 ? -63.103 21.217 0.476 1.00 14.10 ? 163 VAL B CG2 1 ATOM 4315 N N . THR B 1 131 ? -59.458 21.312 0.364 1.00 16.52 ? 164 THR B N 1 ATOM 4316 C CA . THR B 1 131 ? -58.601 22.191 -0.434 1.00 18.99 ? 164 THR B CA 1 ATOM 4317 C C . THR B 1 131 ? -59.520 23.224 -1.187 1.00 20.41 ? 164 THR B C 1 ATOM 4318 O O . THR B 1 131 ? -60.750 22.991 -1.355 1.00 20.28 ? 164 THR B O 1 ATOM 4319 C CB . THR B 1 131 ? -57.686 21.377 -1.437 1.00 20.26 ? 164 THR B CB 1 ATOM 4320 O OG1 . THR B 1 131 ? -56.638 22.195 -2.016 1.00 20.80 ? 164 THR B OG1 1 ATOM 4321 C CG2 . THR B 1 131 ? -58.528 20.796 -2.616 1.00 21.10 ? 164 THR B CG2 1 ATOM 4322 N N . SER B 1 132 ? -58.914 24.334 -1.621 1.00 21.58 ? 165 SER B N 1 ATOM 4323 C CA . SER B 1 132 ? -59.640 25.534 -2.146 1.00 22.10 ? 165 SER B CA 1 ATOM 4324 C C . SER B 1 132 ? -58.622 26.345 -2.922 1.00 22.41 ? 165 SER B C 1 ATOM 4325 O O . SER B 1 132 ? -57.412 26.168 -2.698 1.00 23.83 ? 165 SER B O 1 ATOM 4326 C CB . SER B 1 132 ? -60.245 26.362 -0.997 1.00 21.43 ? 165 SER B CB 1 ATOM 4327 O OG . SER B 1 132 ? -59.211 26.914 -0.143 1.00 24.19 ? 165 SER B OG 1 ATOM 4328 N N . LYS B 1 133 ? -59.059 27.214 -3.834 1.00 24.98 ? 166 LYS B N 1 ATOM 4329 C CA . LYS B 1 133 ? -58.081 28.064 -4.591 1.00 27.09 ? 166 LYS B CA 1 ATOM 4330 C C . LYS B 1 133 ? -57.132 28.903 -3.666 1.00 24.55 ? 166 LYS B C 1 ATOM 4331 O O . LYS B 1 133 ? -55.927 29.067 -3.955 1.00 22.18 ? 166 LYS B O 1 ATOM 4332 C CB . LYS B 1 133 ? -58.756 28.993 -5.621 1.00 27.28 ? 166 LYS B CB 1 ATOM 4333 C CG . LYS B 1 133 ? -57.715 29.670 -6.530 1.00 28.43 ? 166 LYS B CG 1 ATOM 4334 C CD . LYS B 1 133 ? -58.339 30.460 -7.664 1.00 32.02 ? 166 LYS B CD 1 ATOM 4335 C CE . LYS B 1 133 ? -59.083 29.585 -8.667 1.00 32.36 ? 166 LYS B CE 1 ATOM 4336 N NZ . LYS B 1 133 ? -58.500 29.946 -9.985 1.00 35.88 1 166 LYS B NZ 1 ATOM 4337 N N . VAL B 1 134 ? -57.689 29.404 -2.565 1.00 22.62 ? 167 VAL B N 1 ATOM 4338 C CA . VAL B 1 134 ? -56.918 30.234 -1.665 1.00 23.20 ? 167 VAL B CA 1 ATOM 4339 C C . VAL B 1 134 ? -55.806 29.422 -1.003 1.00 21.24 ? 167 VAL B C 1 ATOM 4340 O O . VAL B 1 134 ? -54.597 29.736 -1.088 1.00 20.37 ? 167 VAL B O 1 ATOM 4341 C CB . VAL B 1 134 ? -57.809 30.892 -0.613 1.00 23.68 ? 167 VAL B CB 1 ATOM 4342 C CG1 . VAL B 1 134 ? -56.958 31.580 0.434 1.00 25.02 ? 167 VAL B CG1 1 ATOM 4343 C CG2 . VAL B 1 134 ? -58.678 31.944 -1.269 1.00 24.56 ? 167 VAL B CG2 1 ATOM 4344 N N . TYR B 1 135 ? -56.219 28.365 -0.349 1.00 20.77 ? 168 TYR B N 1 ATOM 4345 C CA . TYR B 1 135 ? -55.244 27.454 0.249 1.00 20.50 ? 168 TYR B CA 1 ATOM 4346 C C . TYR B 1 135 ? -54.117 27.077 -0.773 1.00 20.81 ? 168 TYR B C 1 ATOM 4347 O O . TYR B 1 135 ? -52.925 27.174 -0.448 1.00 20.24 ? 168 TYR B O 1 ATOM 4348 C CB . TYR B 1 135 ? -55.943 26.220 0.877 1.00 18.89 ? 168 TYR B CB 1 ATOM 4349 C CG . TYR B 1 135 ? -56.941 26.463 2.055 1.00 17.38 ? 168 TYR B CG 1 ATOM 4350 C CD1 . TYR B 1 135 ? -57.064 27.671 2.760 1.00 15.53 ? 168 TYR B CD1 1 ATOM 4351 C CD2 . TYR B 1 135 ? -57.725 25.413 2.480 1.00 16.66 ? 168 TYR B CD2 1 ATOM 4352 C CE1 . TYR B 1 135 ? -58.003 27.774 3.790 1.00 14.73 ? 168 TYR B CE1 1 ATOM 4353 C CE2 . TYR B 1 135 ? -58.606 25.518 3.535 1.00 15.27 ? 168 TYR B CE2 1 ATOM 4354 C CZ . TYR B 1 135 ? -58.777 26.671 4.187 1.00 14.41 ? 168 TYR B CZ 1 ATOM 4355 O OH . TYR B 1 135 ? -59.756 26.595 5.245 1.00 13.20 ? 168 TYR B OH 1 ATOM 4356 N N . ASN B 1 136 ? -54.479 26.735 -2.015 1.00 21.08 ? 169 ASN B N 1 ATOM 4357 C CA . ASN B 1 136 ? -53.461 26.399 -3.014 1.00 21.77 ? 169 ASN B CA 1 ATOM 4358 C C . ASN B 1 136 ? -52.650 27.627 -3.446 1.00 22.80 ? 169 ASN B C 1 ATOM 4359 O O . ASN B 1 136 ? -51.513 27.512 -3.916 1.00 24.89 ? 169 ASN B O 1 ATOM 4360 C CB . ASN B 1 136 ? -54.101 25.711 -4.240 1.00 23.18 ? 169 ASN B CB 1 ATOM 4361 C CG . ASN B 1 136 ? -54.570 24.282 -3.938 1.00 25.68 ? 169 ASN B CG 1 ATOM 4362 O OD1 . ASN B 1 136 ? -55.765 23.979 -3.867 1.00 22.84 ? 169 ASN B OD1 1 ATOM 4363 N ND2 . ASN B 1 136 ? -53.610 23.390 -3.739 1.00 27.59 ? 169 ASN B ND2 1 ATOM 4364 N N . ALA B 1 137 ? -53.219 28.820 -3.341 1.00 24.09 ? 170 ALA B N 1 ATOM 4365 C CA . ALA B 1 137 ? -52.457 30.028 -3.727 1.00 23.94 ? 170 ALA B CA 1 ATOM 4366 C C . ALA B 1 137 ? -51.423 30.345 -2.666 1.00 23.74 ? 170 ALA B C 1 ATOM 4367 O O . ALA B 1 137 ? -50.296 30.692 -3.006 1.00 24.15 ? 170 ALA B O 1 ATOM 4368 C CB . ALA B 1 137 ? -53.377 31.238 -3.964 1.00 24.09 ? 170 ALA B CB 1 ATOM 4369 N N . VAL B 1 138 ? -51.801 30.227 -1.389 1.00 23.33 ? 171 VAL B N 1 ATOM 4370 C CA . VAL B 1 138 ? -50.878 30.591 -0.296 1.00 24.53 ? 171 VAL B CA 1 ATOM 4371 C C . VAL B 1 138 ? -49.777 29.537 -0.188 1.00 23.67 ? 171 VAL B C 1 ATOM 4372 O O . VAL B 1 138 ? -48.639 29.893 0.023 1.00 23.30 ? 171 VAL B O 1 ATOM 4373 C CB . VAL B 1 138 ? -51.590 30.866 1.101 1.00 26.71 ? 171 VAL B CB 1 ATOM 4374 C CG1 . VAL B 1 138 ? -52.686 31.923 0.974 1.00 26.12 ? 171 VAL B CG1 1 ATOM 4375 C CG2 . VAL B 1 138 ? -52.162 29.603 1.790 1.00 26.51 ? 171 VAL B CG2 1 ATOM 4376 N N . ALA B 1 139 ? -50.113 28.252 -0.334 1.00 23.98 ? 172 ALA B N 1 ATOM 4377 C CA . ALA B 1 139 ? -49.099 27.197 -0.532 1.00 24.70 ? 172 ALA B CA 1 ATOM 4378 C C . ALA B 1 139 ? -48.034 27.548 -1.636 1.00 25.84 ? 172 ALA B C 1 ATOM 4379 O O . ALA B 1 139 ? -46.808 27.440 -1.404 1.00 25.41 ? 172 ALA B O 1 ATOM 4380 C CB . ALA B 1 139 ? -49.774 25.875 -0.845 1.00 24.83 ? 172 ALA B CB 1 ATOM 4381 N N . ASN B 1 140 ? -48.470 28.017 -2.798 1.00 24.84 ? 173 ASN B N 1 ATOM 4382 C CA . ASN B 1 140 ? -47.489 28.398 -3.800 1.00 28.00 ? 173 ASN B CA 1 ATOM 4383 C C . ASN B 1 140 ? -46.665 29.579 -3.387 1.00 27.48 ? 173 ASN B C 1 ATOM 4384 O O . ASN B 1 140 ? -45.449 29.579 -3.635 1.00 29.75 ? 173 ASN B O 1 ATOM 4385 C CB . ASN B 1 140 ? -48.104 28.694 -5.154 1.00 31.32 ? 173 ASN B CB 1 ATOM 4386 C CG . ASN B 1 140 ? -48.823 27.508 -5.724 1.00 35.47 ? 173 ASN B CG 1 ATOM 4387 O OD1 . ASN B 1 140 ? -48.501 26.340 -5.434 1.00 39.91 ? 173 ASN B OD1 1 ATOM 4388 N ND2 . ASN B 1 140 ? -49.824 27.789 -6.525 1.00 37.18 ? 173 ASN B ND2 1 ATOM 4389 N N . LEU B 1 141 ? -47.311 30.582 -2.789 1.00 25.12 ? 174 LEU B N 1 ATOM 4390 C CA . LEU B 1 141 ? -46.628 31.819 -2.382 1.00 23.39 ? 174 LEU B CA 1 ATOM 4391 C C . LEU B 1 141 ? -45.690 31.584 -1.216 1.00 22.20 ? 174 LEU B C 1 ATOM 4392 O O . LEU B 1 141 ? -44.661 32.230 -1.146 1.00 21.18 ? 174 LEU B O 1 ATOM 4393 C CB . LEU B 1 141 ? -47.625 32.917 -1.978 1.00 24.14 ? 174 LEU B CB 1 ATOM 4394 C CG . LEU B 1 141 ? -48.540 33.462 -3.070 1.00 25.23 ? 174 LEU B CG 1 ATOM 4395 C CD1 . LEU B 1 141 ? -49.823 33.994 -2.434 1.00 27.00 ? 174 LEU B CD1 1 ATOM 4396 C CD2 . LEU B 1 141 ? -47.832 34.525 -3.921 1.00 24.21 ? 174 LEU B CD2 1 ATOM 4397 N N . TRP B 1 142 ? -46.061 30.707 -0.279 1.00 21.99 ? 175 TRP B N 1 ATOM 4398 C CA . TRP B 1 142 ? -45.254 30.506 0.958 1.00 23.00 ? 175 TRP B CA 1 ATOM 4399 C C . TRP B 1 142 ? -44.213 29.342 0.826 1.00 24.84 ? 175 TRP B C 1 ATOM 4400 O O . TRP B 1 142 ? -43.507 29.005 1.769 1.00 24.25 ? 175 TRP B O 1 ATOM 4401 C CB . TRP B 1 142 ? -46.145 30.372 2.226 1.00 20.97 ? 175 TRP B CB 1 ATOM 4402 C CG . TRP B 1 142 ? -47.079 31.552 2.456 1.00 19.73 ? 175 TRP B CG 1 ATOM 4403 C CD1 . TRP B 1 142 ? -46.914 32.866 2.018 1.00 19.04 ? 175 TRP B CD1 1 ATOM 4404 C CD2 . TRP B 1 142 ? -48.331 31.529 3.164 1.00 17.92 ? 175 TRP B CD2 1 ATOM 4405 N NE1 . TRP B 1 142 ? -47.983 33.637 2.436 1.00 18.07 ? 175 TRP B NE1 1 ATOM 4406 C CE2 . TRP B 1 142 ? -48.863 32.839 3.125 1.00 17.31 ? 175 TRP B CE2 1 ATOM 4407 C CE3 . TRP B 1 142 ? -49.075 30.510 3.783 1.00 17.83 ? 175 TRP B CE3 1 ATOM 4408 C CZ2 . TRP B 1 142 ? -50.058 33.152 3.710 1.00 17.16 ? 175 TRP B CZ2 1 ATOM 4409 C CZ3 . TRP B 1 142 ? -50.299 30.816 4.354 1.00 16.78 ? 175 TRP B CZ3 1 ATOM 4410 C CH2 . TRP B 1 142 ? -50.771 32.115 4.311 1.00 17.85 ? 175 TRP B CH2 1 ATOM 4411 N N . LYS B 1 143 ? -44.109 28.775 -0.373 1.00 28.89 ? 176 LYS B N 1 ATOM 4412 C CA . LYS B 1 143 ? -43.112 27.743 -0.682 1.00 30.15 ? 176 LYS B CA 1 ATOM 4413 C C . LYS B 1 143 ? -41.669 28.099 -0.312 1.00 28.25 ? 176 LYS B C 1 ATOM 4414 O O . LYS B 1 143 ? -40.907 27.245 0.099 1.00 28.93 ? 176 LYS B O 1 ATOM 4415 C CB . LYS B 1 143 ? -43.173 27.410 -2.174 1.00 34.49 ? 176 LYS B CB 1 ATOM 4416 C CG . LYS B 1 143 ? -43.883 26.104 -2.498 1.00 39.19 ? 176 LYS B CG 1 ATOM 4417 C CD . LYS B 1 143 ? -44.198 25.920 -3.992 1.00 44.04 ? 176 LYS B CD 1 ATOM 4418 C CE . LYS B 1 143 ? -43.264 26.692 -4.926 1.00 48.52 ? 176 LYS B CE 1 ATOM 4419 N NZ . LYS B 1 143 ? -43.983 27.078 -6.185 1.00 54.16 1 176 LYS B NZ 1 ATOM 4420 N N . PRO B 1 144 ? -41.266 29.350 -0.513 1.00 27.82 ? 177 PRO B N 1 ATOM 4421 C CA . PRO B 1 144 ? -39.920 29.733 -0.106 1.00 27.71 ? 177 PRO B CA 1 ATOM 4422 C C . PRO B 1 144 ? -39.632 29.545 1.400 1.00 29.81 ? 177 PRO B C 1 ATOM 4423 O O . PRO B 1 144 ? -38.490 29.289 1.794 1.00 29.02 ? 177 PRO B O 1 ATOM 4424 C CB . PRO B 1 144 ? -39.872 31.223 -0.464 1.00 27.98 ? 177 PRO B CB 1 ATOM 4425 C CG . PRO B 1 144 ? -40.805 31.356 -1.629 1.00 26.94 ? 177 PRO B CG 1 ATOM 4426 C CD . PRO B 1 144 ? -41.914 30.383 -1.348 1.00 27.67 ? 177 PRO B CD 1 ATOM 4427 N N . TRP B 1 145 ? -40.668 29.665 2.231 1.00 30.30 ? 178 TRP B N 1 ATOM 4428 C CA . TRP B 1 145 ? -40.504 29.601 3.702 1.00 29.44 ? 178 TRP B CA 1 ATOM 4429 C C . TRP B 1 145 ? -40.756 28.224 4.346 1.00 29.97 ? 178 TRP B C 1 ATOM 4430 O O . TRP B 1 145 ? -40.451 28.022 5.539 1.00 29.31 ? 178 TRP B O 1 ATOM 4431 C CB . TRP B 1 145 ? -41.438 30.625 4.386 1.00 25.60 ? 178 TRP B CB 1 ATOM 4432 C CG . TRP B 1 145 ? -41.172 32.005 4.001 1.00 23.09 ? 178 TRP B CG 1 ATOM 4433 C CD1 . TRP B 1 145 ? -39.970 32.554 3.804 1.00 22.44 ? 178 TRP B CD1 1 ATOM 4434 C CD2 . TRP B 1 145 ? -42.144 33.049 3.766 1.00 22.36 ? 178 TRP B CD2 1 ATOM 4435 N NE1 . TRP B 1 145 ? -40.099 33.884 3.461 1.00 22.38 ? 178 TRP B NE1 1 ATOM 4436 C CE2 . TRP B 1 145 ? -41.422 34.217 3.442 1.00 21.46 ? 178 TRP B CE2 1 ATOM 4437 C CE3 . TRP B 1 145 ? -43.546 33.113 3.831 1.00 20.99 ? 178 TRP B CE3 1 ATOM 4438 C CZ2 . TRP B 1 145 ? -42.039 35.434 3.188 1.00 21.74 ? 178 TRP B CZ2 1 ATOM 4439 C CZ3 . TRP B 1 145 ? -44.165 34.331 3.570 1.00 21.47 ? 178 TRP B CZ3 1 ATOM 4440 C CH2 . TRP B 1 145 ? -43.413 35.473 3.249 1.00 21.98 ? 178 TRP B CH2 1 ATOM 4441 N N . LEU B 1 146 ? -41.371 27.319 3.598 1.00 29.96 ? 179 LEU B N 1 ATOM 4442 C CA . LEU B 1 146 ? -41.899 26.102 4.181 1.00 31.67 ? 179 LEU B CA 1 ATOM 4443 C C . LEU B 1 146 ? -41.419 24.886 3.340 1.00 33.65 ? 179 LEU B C 1 ATOM 4444 O O . LEU B 1 146 ? -41.119 25.027 2.135 1.00 35.31 ? 179 LEU B O 1 ATOM 4445 C CB . LEU B 1 146 ? -43.444 26.231 4.293 1.00 30.55 ? 179 LEU B CB 1 ATOM 4446 C CG . LEU B 1 146 ? -43.999 27.525 4.961 1.00 29.96 ? 179 LEU B CG 1 ATOM 4447 C CD1 . LEU B 1 146 ? -45.541 27.545 5.117 1.00 31.15 ? 179 LEU B CD1 1 ATOM 4448 C CD2 . LEU B 1 146 ? -43.379 27.787 6.321 1.00 28.34 ? 179 LEU B CD2 1 ATOM 4449 N N . ASP B 1 147 ? -41.331 23.711 3.983 1.00 34.02 ? 180 ASP B N 1 ATOM 4450 C CA . ASP B 1 147 ? -41.025 22.416 3.312 1.00 31.51 ? 180 ASP B CA 1 ATOM 4451 C C . ASP B 1 147 ? -42.277 21.779 2.682 1.00 30.56 ? 180 ASP B C 1 ATOM 4452 O O . ASP B 1 147 ? -43.381 22.224 2.958 1.00 29.35 ? 180 ASP B O 1 ATOM 4453 C CB . ASP B 1 147 ? -40.381 21.453 4.311 1.00 32.38 ? 180 ASP B CB 1 ATOM 4454 C CG . ASP B 1 147 ? -39.010 21.948 4.818 1.00 36.33 ? 180 ASP B CG 1 ATOM 4455 O OD1 . ASP B 1 147 ? -38.366 22.795 4.144 1.00 39.41 ? 180 ASP B OD1 1 ATOM 4456 O OD2 . ASP B 1 147 ? -38.562 21.491 5.906 1.00 40.37 -1 180 ASP B OD2 1 ATOM 4457 N N . GLU B 1 148 ? -42.083 20.753 1.843 1.00 32.82 ? 181 GLU B N 1 ATOM 4458 C CA . GLU B 1 148 ? -43.152 20.060 1.088 1.00 34.57 ? 181 GLU B CA 1 ATOM 4459 C C . GLU B 1 148 ? -44.272 19.484 1.957 1.00 31.49 ? 181 GLU B C 1 ATOM 4460 O O . GLU B 1 148 ? -45.396 19.420 1.519 1.00 27.69 ? 181 GLU B O 1 ATOM 4461 C CB . GLU B 1 148 ? -42.590 18.876 0.276 1.00 43.08 ? 181 GLU B CB 1 ATOM 4462 C CG . GLU B 1 148 ? -41.468 19.192 -0.722 1.00 53.63 ? 181 GLU B CG 1 ATOM 4463 C CD . GLU B 1 148 ? -40.353 18.115 -0.778 1.00 63.19 ? 181 GLU B CD 1 ATOM 4464 O OE1 . GLU B 1 148 ? -39.514 18.159 -1.710 1.00 62.22 ? 181 GLU B OE1 1 ATOM 4465 O OE2 . GLU B 1 148 ? -40.294 17.220 0.109 1.00 65.51 -1 181 GLU B OE2 1 ATOM 4466 N N . GLU B 1 149 ? -43.953 19.036 3.170 1.00 30.79 ? 182 GLU B N 1 ATOM 4467 C CA . GLU B 1 149 ? -44.925 18.411 4.075 1.00 30.24 ? 182 GLU B CA 1 ATOM 4468 C C . GLU B 1 149 ? -45.864 19.488 4.608 1.00 26.58 ? 182 GLU B C 1 ATOM 4469 O O . GLU B 1 149 ? -47.088 19.303 4.718 1.00 25.35 ? 182 GLU B O 1 ATOM 4470 C CB . GLU B 1 149 ? -44.200 17.707 5.244 1.00 34.92 ? 182 GLU B CB 1 ATOM 4471 C CG . GLU B 1 149 ? -43.207 16.580 4.868 1.00 41.16 ? 182 GLU B CG 1 ATOM 4472 C CD . GLU B 1 149 ? -41.768 17.012 4.434 1.00 45.40 ? 182 GLU B CD 1 ATOM 4473 O OE1 . GLU B 1 149 ? -41.425 18.217 4.329 1.00 42.79 ? 182 GLU B OE1 1 ATOM 4474 O OE2 . GLU B 1 149 ? -40.940 16.096 4.192 1.00 50.12 -1 182 GLU B OE2 1 ATOM 4475 N N . ALA B 1 150 ? -45.290 20.630 4.933 1.00 23.70 ? 183 ALA B N 1 ATOM 4476 C CA . ALA B 1 150 ? -46.105 21.750 5.369 1.00 25.05 ? 183 ALA B CA 1 ATOM 4477 C C . ALA B 1 150 ? -46.927 22.279 4.209 1.00 25.55 ? 183 ALA B C 1 ATOM 4478 O O . ALA B 1 150 ? -48.093 22.648 4.409 1.00 27.42 ? 183 ALA B O 1 ATOM 4479 C CB . ALA B 1 150 ? -45.255 22.858 6.000 1.00 25.05 ? 183 ALA B CB 1 ATOM 4480 N N . ILE B 1 151 ? -46.323 22.352 3.020 1.00 25.24 ? 184 ILE B N 1 ATOM 4481 C CA . ILE B 1 151 ? -47.037 22.778 1.843 1.00 27.61 ? 184 ILE B CA 1 ATOM 4482 C C . ILE B 1 151 ? -48.217 21.827 1.570 1.00 29.75 ? 184 ILE B C 1 ATOM 4483 O O . ILE B 1 151 ? -49.286 22.310 1.286 1.00 31.61 ? 184 ILE B O 1 ATOM 4484 C CB . ILE B 1 151 ? -46.123 22.926 0.590 1.00 28.28 ? 184 ILE B CB 1 ATOM 4485 C CG1 . ILE B 1 151 ? -45.131 24.082 0.775 1.00 29.05 ? 184 ILE B CG1 1 ATOM 4486 C CG2 . ILE B 1 151 ? -46.955 23.231 -0.657 1.00 27.59 ? 184 ILE B CG2 1 ATOM 4487 C CD1 . ILE B 1 151 ? -45.798 25.415 1.131 1.00 29.77 ? 184 ILE B CD1 1 ATOM 4488 N N . SER B 1 152 ? -48.055 20.502 1.687 1.00 30.39 ? 185 SER B N 1 ATOM 4489 C CA . SER B 1 152 ? -49.184 19.593 1.392 1.00 30.96 ? 185 SER B CA 1 ATOM 4490 C C . SER B 1 152 ? -50.309 19.916 2.327 1.00 30.38 ? 185 SER B C 1 ATOM 4491 O O . SER B 1 152 ? -51.457 19.907 1.934 1.00 36.20 ? 185 SER B O 1 ATOM 4492 C CB . SER B 1 152 ? -48.912 18.077 1.556 1.00 28.93 ? 185 SER B CB 1 ATOM 4493 O OG . SER B 1 152 ? -47.602 17.765 1.914 1.00 32.15 ? 185 SER B OG 1 ATOM 4494 N N . THR B 1 153 ? -49.975 20.160 3.579 1.00 27.59 ? 186 THR B N 1 ATOM 4495 C CA . THR B 1 153 ? -50.985 20.285 4.617 1.00 26.26 ? 186 THR B CA 1 ATOM 4496 C C . THR B 1 153 ? -51.660 21.649 4.509 1.00 22.54 ? 186 THR B C 1 ATOM 4497 O O . THR B 1 153 ? -52.849 21.742 4.678 1.00 20.05 ? 186 THR B O 1 ATOM 4498 C CB . THR B 1 153 ? -50.361 19.960 6.013 1.00 26.65 ? 186 THR B CB 1 ATOM 4499 O OG1 . THR B 1 153 ? -49.860 18.623 5.983 1.00 27.50 ? 186 THR B OG1 1 ATOM 4500 C CG2 . THR B 1 153 ? -51.352 20.005 7.123 1.00 27.17 ? 186 THR B CG2 1 ATOM 4501 N N . LEU B 1 154 ? -50.919 22.679 4.155 1.00 20.31 ? 187 LEU B N 1 ATOM 4502 C CA . LEU B 1 154 ? -51.538 23.965 3.921 1.00 21.45 ? 187 LEU B CA 1 ATOM 4503 C C . LEU B 1 154 ? -52.677 23.884 2.836 1.00 21.09 ? 187 LEU B C 1 ATOM 4504 O O . LEU B 1 154 ? -53.831 24.335 3.020 1.00 18.09 ? 187 LEU B O 1 ATOM 4505 C CB . LEU B 1 154 ? -50.421 24.944 3.536 1.00 22.94 ? 187 LEU B CB 1 ATOM 4506 C CG . LEU B 1 154 ? -50.607 26.477 3.449 1.00 25.31 ? 187 LEU B CG 1 ATOM 4507 C CD1 . LEU B 1 154 ? -51.335 27.082 4.646 1.00 24.90 ? 187 LEU B CD1 1 ATOM 4508 C CD2 . LEU B 1 154 ? -49.235 27.138 3.245 1.00 26.81 ? 187 LEU B CD2 1 ATOM 4509 N N . ARG B 1 155 ? -52.333 23.264 1.713 1.00 23.09 ? 188 ARG B N 1 ATOM 4510 C CA . ARG B 1 155 ? -53.244 23.041 0.574 1.00 25.13 ? 188 ARG B CA 1 ATOM 4511 C C . ARG B 1 155 ? -54.600 22.428 0.963 1.00 27.20 ? 188 ARG B C 1 ATOM 4512 O O . ARG B 1 155 ? -55.591 22.764 0.319 1.00 24.76 ? 188 ARG B O 1 ATOM 4513 C CB . ARG B 1 155 ? -52.609 22.124 -0.467 1.00 25.33 ? 188 ARG B CB 1 ATOM 4514 C CG . ARG B 1 155 ? -51.363 22.642 -1.175 1.00 25.89 ? 188 ARG B CG 1 ATOM 4515 C CD . ARG B 1 155 ? -51.036 21.771 -2.404 1.00 25.68 ? 188 ARG B CD 1 ATOM 4516 N NE . ARG B 1 155 ? -49.816 22.231 -3.032 1.00 26.02 ? 188 ARG B NE 1 ATOM 4517 C CZ . ARG B 1 155 ? -49.674 23.366 -3.724 1.00 27.04 ? 188 ARG B CZ 1 ATOM 4518 N NH1 . ARG B 1 155 ? -50.676 24.217 -3.937 1.00 26.96 1 188 ARG B NH1 1 ATOM 4519 N NH2 . ARG B 1 155 ? -48.479 23.677 -4.197 1.00 28.96 ? 188 ARG B NH2 1 ATOM 4520 N N . LYS B 1 156 ? -54.618 21.555 1.990 1.00 28.02 ? 189 LYS B N 1 ATOM 4521 C CA . LYS B 1 156 ? -55.803 20.763 2.414 1.00 29.62 ? 189 LYS B CA 1 ATOM 4522 C C . LYS B 1 156 ? -56.758 21.504 3.430 1.00 28.07 ? 189 LYS B C 1 ATOM 4523 O O . LYS B 1 156 ? -58.003 21.446 3.310 1.00 27.03 ? 189 LYS B O 1 ATOM 4524 C CB . LYS B 1 156 ? -55.329 19.352 2.814 1.00 35.13 ? 189 LYS B CB 1 ATOM 4525 C CG . LYS B 1 156 ? -55.083 18.401 1.646 1.00 41.51 ? 189 LYS B CG 1 ATOM 4526 C CD . LYS B 1 156 ? -53.627 18.001 1.450 1.00 46.72 ? 189 LYS B CD 1 ATOM 4527 C CE . LYS B 1 156 ? -53.383 17.412 0.046 1.00 53.30 ? 189 LYS B CE 1 ATOM 4528 N NZ . LYS B 1 156 ? -51.994 17.689 -0.469 1.00 52.97 1 189 LYS B NZ 1 ATOM 4529 N N . GLY B 1 157 ? -56.186 22.130 4.451 1.00 26.29 ? 190 GLY B N 1 ATOM 4530 C CA . GLY B 1 157 ? -56.968 22.839 5.454 1.00 27.71 ? 190 GLY B CA 1 ATOM 4531 C C . GLY B 1 157 ? -56.371 24.142 6.007 1.00 28.69 ? 190 GLY B C 1 ATOM 4532 O O . GLY B 1 157 ? -56.790 24.591 7.078 1.00 29.51 ? 190 GLY B O 1 ATOM 4533 N N . GLY B 1 158 ? -55.428 24.768 5.280 1.00 29.64 ? 191 GLY B N 1 ATOM 4534 C CA . GLY B 1 158 ? -54.807 26.079 5.668 1.00 28.34 ? 191 GLY B CA 1 ATOM 4535 C C . GLY B 1 158 ? -53.950 26.099 6.949 1.00 27.01 ? 191 GLY B C 1 ATOM 4536 O O . GLY B 1 158 ? -53.730 27.172 7.488 1.00 23.17 ? 191 GLY B O 1 ATOM 4537 N N . PHE B 1 159 ? -53.507 24.898 7.424 1.00 25.20 ? 192 PHE B N 1 ATOM 4538 C CA . PHE B 1 159 ? -52.679 24.680 8.638 1.00 20.03 ? 192 PHE B CA 1 ATOM 4539 C C . PHE B 1 159 ? -51.469 23.838 8.269 1.00 18.85 ? 192 PHE B C 1 ATOM 4540 O O . PHE B 1 159 ? -51.527 23.203 7.223 1.00 17.25 ? 192 PHE B O 1 ATOM 4541 C CB . PHE B 1 159 ? -53.479 24.066 9.761 1.00 18.69 ? 192 PHE B CB 1 ATOM 4542 C CG . PHE B 1 159 ? -54.016 22.659 9.504 1.00 20.18 ? 192 PHE B CG 1 ATOM 4543 C CD1 . PHE B 1 159 ? -53.193 21.529 9.578 1.00 21.06 ? 192 PHE B CD1 1 ATOM 4544 C CD2 . PHE B 1 159 ? -55.404 22.438 9.305 1.00 18.92 ? 192 PHE B CD2 1 ATOM 4545 C CE1 . PHE B 1 159 ? -53.739 20.243 9.363 1.00 20.08 ? 192 PHE B CE1 1 ATOM 4546 C CE2 . PHE B 1 159 ? -55.927 21.187 9.130 1.00 17.60 ? 192 PHE B CE2 1 ATOM 4547 C CZ . PHE B 1 159 ? -55.095 20.084 9.144 1.00 18.65 ? 192 PHE B CZ 1 ATOM 4548 N N . TYR B 1 160 ? -50.375 23.897 9.072 1.00 18.15 ? 193 TYR B N 1 ATOM 4549 C CA . TYR B 1 160 ? -49.065 23.128 8.831 1.00 17.12 ? 193 TYR B CA 1 ATOM 4550 C C . TYR B 1 160 ? -48.096 23.162 10.040 1.00 15.82 ? 193 TYR B C 1 ATOM 4551 O O . TYR B 1 160 ? -48.308 23.949 10.946 1.00 17.23 ? 193 TYR B O 1 ATOM 4552 C CB . TYR B 1 160 ? -48.258 23.697 7.659 1.00 17.50 ? 193 TYR B CB 1 ATOM 4553 C CG . TYR B 1 160 ? -47.713 25.111 7.925 1.00 18.13 ? 193 TYR B CG 1 ATOM 4554 C CD1 . TYR B 1 160 ? -48.503 26.241 7.649 1.00 19.18 ? 193 TYR B CD1 1 ATOM 4555 C CD2 . TYR B 1 160 ? -46.431 25.327 8.447 1.00 17.06 ? 193 TYR B CD2 1 ATOM 4556 C CE1 . TYR B 1 160 ? -48.024 27.539 7.862 1.00 19.00 ? 193 TYR B CE1 1 ATOM 4557 C CE2 . TYR B 1 160 ? -45.965 26.607 8.690 1.00 17.25 ? 193 TYR B CE2 1 ATOM 4558 C CZ . TYR B 1 160 ? -46.764 27.732 8.412 1.00 18.39 ? 193 TYR B CZ 1 ATOM 4559 O OH . TYR B 1 160 ? -46.349 29.076 8.666 1.00 18.26 ? 193 TYR B OH 1 ATOM 4560 N N . SER B 1 161 ? -47.021 22.391 10.047 1.00 13.13 ? 194 SER B N 1 ATOM 4561 C CA . SER B 1 161 ? -45.980 22.637 11.020 1.00 12.90 ? 194 SER B CA 1 ATOM 4562 C C . SER B 1 161 ? -44.676 22.698 10.242 1.00 14.50 ? 194 SER B C 1 ATOM 4563 O O . SER B 1 161 ? -44.627 22.247 9.128 1.00 15.39 ? 194 SER B O 1 ATOM 4564 C CB . SER B 1 161 ? -45.935 21.636 12.183 1.00 11.80 ? 194 SER B CB 1 ATOM 4565 O OG . SER B 1 161 ? -45.454 20.347 11.814 1.00 11.11 ? 194 SER B OG 1 ATOM 4566 N N . GLN B 1 162 ? -43.653 23.330 10.812 1.00 16.46 ? 195 GLN B N 1 ATOM 4567 C CA . GLN B 1 162 ? -42.368 23.616 10.123 1.00 17.17 ? 195 GLN B CA 1 ATOM 4568 C C . GLN B 1 162 ? -41.324 23.880 11.167 1.00 17.18 ? 195 GLN B C 1 ATOM 4569 O O . GLN B 1 162 ? -41.577 24.591 12.141 1.00 16.50 ? 195 GLN B O 1 ATOM 4570 C CB . GLN B 1 162 ? -42.462 24.866 9.221 1.00 17.39 ? 195 GLN B CB 1 ATOM 4571 C CG . GLN B 1 162 ? -41.223 25.260 8.409 1.00 16.71 ? 195 GLN B CG 1 ATOM 4572 C CD . GLN B 1 162 ? -40.835 24.191 7.367 1.00 17.39 ? 195 GLN B CD 1 ATOM 4573 O OE1 . GLN B 1 162 ? -41.656 23.742 6.523 1.00 17.56 ? 195 GLN B OE1 1 ATOM 4574 N NE2 . GLN B 1 162 ? -39.582 23.766 7.423 1.00 16.47 ? 195 GLN B NE2 1 ATOM 4575 N N . LYS B 1 163 ? -40.169 23.253 10.968 1.00 18.20 ? 196 LYS B N 1 ATOM 4576 C CA . LYS B 1 163 ? -39.046 23.406 11.849 1.00 18.42 ? 196 LYS B CA 1 ATOM 4577 C C . LYS B 1 163 ? -38.322 24.709 11.483 1.00 19.06 ? 196 LYS B C 1 ATOM 4578 O O . LYS B 1 163 ? -38.283 25.079 10.321 1.00 17.86 ? 196 LYS B O 1 ATOM 4579 C CB . LYS B 1 163 ? -38.144 22.222 11.708 1.00 18.61 ? 196 LYS B CB 1 ATOM 4580 C CG . LYS B 1 163 ? -38.590 21.045 12.520 1.00 19.85 ? 196 LYS B CG 1 ATOM 4581 C CD . LYS B 1 163 ? -37.760 19.827 12.117 1.00 22.29 ? 196 LYS B CD 1 ATOM 4582 C CE . LYS B 1 163 ? -38.187 19.314 10.742 1.00 22.67 ? 196 LYS B CE 1 ATOM 4583 N NZ . LYS B 1 163 ? -37.701 17.966 10.578 1.00 23.42 1 196 LYS B NZ 1 ATOM 4584 N N . VAL B 1 164 ? -37.791 25.421 12.480 1.00 18.88 ? 197 VAL B N 1 ATOM 4585 C CA . VAL B 1 164 ? -37.206 26.719 12.214 1.00 20.03 ? 197 VAL B CA 1 ATOM 4586 C C . VAL B 1 164 ? -35.866 26.424 11.592 1.00 21.45 ? 197 VAL B C 1 ATOM 4587 O O . VAL B 1 164 ? -35.092 25.649 12.165 1.00 22.74 ? 197 VAL B O 1 ATOM 4588 C CB . VAL B 1 164 ? -37.009 27.602 13.506 1.00 19.41 ? 197 VAL B CB 1 ATOM 4589 C CG1 . VAL B 1 164 ? -36.225 28.877 13.150 1.00 19.39 ? 197 VAL B CG1 1 ATOM 4590 C CG2 . VAL B 1 164 ? -38.327 27.936 14.194 1.00 17.61 ? 197 VAL B CG2 1 ATOM 4591 N N . THR B 1 165 ? -35.551 27.038 10.459 1.00 22.99 ? 198 THR B N 1 ATOM 4592 C CA . THR B 1 165 ? -34.238 26.750 9.851 1.00 25.77 ? 198 THR B CA 1 ATOM 4593 C C . THR B 1 165 ? -33.011 26.995 10.770 1.00 25.16 ? 198 THR B C 1 ATOM 4594 O O . THR B 1 165 ? -32.052 26.245 10.707 1.00 23.52 ? 198 THR B O 1 ATOM 4595 C CB . THR B 1 165 ? -33.996 27.531 8.555 1.00 26.90 ? 198 THR B CB 1 ATOM 4596 O OG1 . THR B 1 165 ? -34.956 27.127 7.611 1.00 26.60 ? 198 THR B OG1 1 ATOM 4597 C CG2 . THR B 1 165 ? -32.608 27.192 7.984 1.00 28.08 ? 198 THR B CG2 1 ATOM 4598 N N . THR B 1 166 ? -33.046 28.076 11.548 1.00 24.97 ? 199 THR B N 1 ATOM 4599 C CA . THR B 1 166 ? -31.964 28.418 12.483 1.00 25.30 ? 199 THR B CA 1 ATOM 4600 C C . THR B 1 166 ? -32.039 27.655 13.838 1.00 23.85 ? 199 THR B C 1 ATOM 4601 O O . THR B 1 166 ? -31.081 27.677 14.572 1.00 22.16 ? 199 THR B O 1 ATOM 4602 C CB . THR B 1 166 ? -31.882 29.950 12.778 1.00 24.79 ? 199 THR B CB 1 ATOM 4603 O OG1 . THR B 1 166 ? -33.035 30.374 13.499 1.00 23.53 ? 199 THR B OG1 1 ATOM 4604 C CG2 . THR B 1 166 ? -31.788 30.747 11.488 1.00 24.89 ? 199 THR B CG2 1 ATOM 4605 N N . ASN B 1 167 ? -33.172 27.025 14.158 1.00 22.49 ? 200 ASN B N 1 ATOM 4606 C CA . ASN B 1 167 ? -33.313 26.232 15.372 1.00 22.00 ? 200 ASN B CA 1 ATOM 4607 C C . ASN B 1 167 ? -34.134 24.973 15.094 1.00 22.95 ? 200 ASN B C 1 ATOM 4608 O O . ASN B 1 167 ? -35.280 24.853 15.537 1.00 23.30 ? 200 ASN B O 1 ATOM 4609 C CB . ASN B 1 167 ? -33.951 27.054 16.463 1.00 20.47 ? 200 ASN B CB 1 ATOM 4610 C CG . ASN B 1 167 ? -33.073 28.174 16.874 1.00 20.55 ? 200 ASN B CG 1 ATOM 4611 O OD1 . ASN B 1 167 ? -32.342 28.096 17.858 1.00 19.66 ? 200 ASN B OD1 1 ATOM 4612 N ND2 . ASN B 1 167 ? -33.085 29.221 16.077 1.00 20.96 ? 200 ASN B ND2 1 ATOM 4613 N N . PRO B 1 168 ? -33.544 23.998 14.383 1.00 22.19 ? 201 PRO B N 1 ATOM 4614 C CA . PRO B 1 168 ? -34.399 22.916 13.846 1.00 21.57 ? 201 PRO B CA 1 ATOM 4615 C C . PRO B 1 168 ? -35.136 22.001 14.875 1.00 19.71 ? 201 PRO B C 1 ATOM 4616 O O . PRO B 1 168 ? -35.961 21.205 14.454 1.00 17.32 ? 201 PRO B O 1 ATOM 4617 C CB . PRO B 1 168 ? -33.433 22.134 12.928 1.00 22.67 ? 201 PRO B CB 1 ATOM 4618 C CG . PRO B 1 168 ? -32.245 23.043 12.736 1.00 22.87 ? 201 PRO B CG 1 ATOM 4619 C CD . PRO B 1 168 ? -32.134 23.838 13.995 1.00 21.79 ? 201 PRO B CD 1 ATOM 4620 N N . ASN B 1 169 ? -34.837 22.144 16.184 1.00 20.09 ? 202 ASN B N 1 ATOM 4621 C CA . ASN B 1 169 ? -35.613 21.511 17.313 1.00 20.27 ? 202 ASN B CA 1 ATOM 4622 C C . ASN B 1 169 ? -36.797 22.417 17.823 1.00 19.74 ? 202 ASN B C 1 ATOM 4623 O O . ASN B 1 169 ? -37.560 22.050 18.711 1.00 18.96 ? 202 ASN B O 1 ATOM 4624 C CB . ASN B 1 169 ? -34.688 21.044 18.481 1.00 20.59 ? 202 ASN B CB 1 ATOM 4625 C CG . ASN B 1 169 ? -33.727 22.162 18.990 1.00 21.67 ? 202 ASN B CG 1 ATOM 4626 O OD1 . ASN B 1 169 ? -33.613 23.196 18.355 1.00 23.95 ? 202 ASN B OD1 1 ATOM 4627 N ND2 . ASN B 1 169 ? -33.055 21.951 20.127 1.00 20.69 ? 202 ASN B ND2 1 ATOM 4628 N N . LEU B 1 170 ? -36.956 23.594 17.234 1.00 18.98 ? 203 LEU B N 1 ATOM 4629 C CA . LEU B 1 170 ? -38.083 24.440 17.542 1.00 18.11 ? 203 LEU B CA 1 ATOM 4630 C C . LEU B 1 170 ? -39.033 24.268 16.384 1.00 18.70 ? 203 LEU B C 1 ATOM 4631 O O . LEU B 1 170 ? -38.687 24.464 15.201 1.00 17.67 ? 203 LEU B O 1 ATOM 4632 C CB . LEU B 1 170 ? -37.644 25.877 17.711 1.00 18.51 ? 203 LEU B CB 1 ATOM 4633 C CG . LEU B 1 170 ? -38.790 26.874 17.828 1.00 20.03 ? 203 LEU B CG 1 ATOM 4634 C CD1 . LEU B 1 170 ? -39.570 26.639 19.122 1.00 21.57 ? 203 LEU B CD1 1 ATOM 4635 C CD2 . LEU B 1 170 ? -38.327 28.319 17.767 1.00 19.40 ? 203 LEU B CD2 1 ATOM 4636 N N . ARG B 1 171 ? -40.237 23.818 16.701 1.00 19.19 ? 204 ARG B N 1 ATOM 4637 C CA . ARG B 1 171 ? -41.206 23.611 15.637 1.00 18.38 ? 204 ARG B CA 1 ATOM 4638 C C . ARG B 1 171 ? -42.334 24.571 15.836 1.00 16.54 ? 204 ARG B C 1 ATOM 4639 O O . ARG B 1 171 ? -42.968 24.530 16.883 1.00 15.13 ? 204 ARG B O 1 ATOM 4640 C CB . ARG B 1 171 ? -41.771 22.181 15.715 1.00 19.36 ? 204 ARG B CB 1 ATOM 4641 C CG . ARG B 1 171 ? -42.859 21.853 14.683 1.00 18.59 ? 204 ARG B CG 1 ATOM 4642 C CD . ARG B 1 171 ? -43.483 20.505 14.957 1.00 19.16 ? 204 ARG B CD 1 ATOM 4643 N NE . ARG B 1 171 ? -42.509 19.442 14.738 1.00 20.26 ? 204 ARG B NE 1 ATOM 4644 C CZ . ARG B 1 171 ? -42.080 19.052 13.541 1.00 19.37 ? 204 ARG B CZ 1 ATOM 4645 N NH1 . ARG B 1 171 ? -42.570 19.588 12.442 1.00 19.59 1 204 ARG B NH1 1 ATOM 4646 N NH2 . ARG B 1 171 ? -41.181 18.104 13.451 1.00 18.47 ? 204 ARG B NH2 1 ATOM 4647 N N . ILE B 1 172 ? -42.577 25.382 14.810 1.00 14.65 ? 205 ILE B N 1 ATOM 4648 C CA . ILE B 1 172 ? -43.798 26.241 14.673 1.00 14.58 ? 205 ILE B CA 1 ATOM 4649 C C . ILE B 1 172 ? -45.065 25.449 14.188 1.00 14.22 ? 205 ILE B C 1 ATOM 4650 O O . ILE B 1 172 ? -44.984 24.743 13.146 1.00 14.12 ? 205 ILE B O 1 ATOM 4651 C CB . ILE B 1 172 ? -43.542 27.396 13.640 1.00 14.27 ? 205 ILE B CB 1 ATOM 4652 C CG1 . ILE B 1 172 ? -42.321 28.235 14.016 1.00 14.44 ? 205 ILE B CG1 1 ATOM 4653 C CG2 . ILE B 1 172 ? -44.721 28.325 13.563 1.00 15.48 ? 205 ILE B CG2 1 ATOM 4654 C CD1 . ILE B 1 172 ? -42.195 28.650 15.485 1.00 14.78 ? 205 ILE B CD1 1 ATOM 4655 N N . ILE B 1 173 ? -46.198 25.544 14.907 1.00 12.82 ? 206 ILE B N 1 ATOM 4656 C CA . ILE B 1 173 ? -47.455 24.887 14.470 1.00 12.26 ? 206 ILE B CA 1 ATOM 4657 C C . ILE B 1 173 ? -48.320 26.070 14.112 1.00 12.67 ? 206 ILE B C 1 ATOM 4658 O O . ILE B 1 173 ? -48.513 26.930 14.930 1.00 11.52 ? 206 ILE B O 1 ATOM 4659 C CB . ILE B 1 173 ? -48.106 24.041 15.570 1.00 12.28 ? 206 ILE B CB 1 ATOM 4660 C CG1 . ILE B 1 173 ? -47.204 22.848 15.870 1.00 12.44 ? 206 ILE B CG1 1 ATOM 4661 C CG2 . ILE B 1 173 ? -49.527 23.622 15.177 1.00 12.54 ? 206 ILE B CG2 1 ATOM 4662 C CD1 . ILE B 1 173 ? -47.587 22.081 17.071 1.00 11.99 ? 206 ILE B CD1 1 ATOM 4663 N N . SER B 1 174 ? -48.777 26.133 12.856 1.00 13.76 ? 207 SER B N 1 ATOM 4664 C CA . SER B 1 174 ? -49.592 27.268 12.322 1.00 14.29 ? 207 SER B CA 1 ATOM 4665 C C . SER B 1 174 ? -51.013 26.769 12.076 1.00 14.04 ? 207 SER B C 1 ATOM 4666 O O . SER B 1 174 ? -51.271 26.125 11.071 1.00 15.02 ? 207 SER B O 1 ATOM 4667 C CB . SER B 1 174 ? -49.012 27.831 11.012 1.00 14.38 ? 207 SER B CB 1 ATOM 4668 O OG . SER B 1 174 ? -49.741 28.972 10.529 1.00 13.91 ? 207 SER B OG 1 ATOM 4669 N N . LEU B 1 175 ? -51.883 27.029 13.036 1.00 14.13 ? 208 LEU B N 1 ATOM 4670 C CA . LEU B 1 175 ? -53.258 26.585 13.012 1.00 15.00 ? 208 LEU B CA 1 ATOM 4671 C C . LEU B 1 175 ? -54.163 27.549 12.233 1.00 16.51 ? 208 LEU B C 1 ATOM 4672 O O . LEU B 1 175 ? -53.906 28.795 12.124 1.00 16.53 ? 208 LEU B O 1 ATOM 4673 C CB . LEU B 1 175 ? -53.837 26.431 14.428 1.00 14.50 ? 208 LEU B CB 1 ATOM 4674 C CG . LEU B 1 175 ? -53.113 25.409 15.298 1.00 15.11 ? 208 LEU B CG 1 ATOM 4675 C CD1 . LEU B 1 175 ? -53.705 25.424 16.691 1.00 15.37 ? 208 LEU B CD1 1 ATOM 4676 C CD2 . LEU B 1 175 ? -53.191 24.017 14.737 1.00 14.79 ? 208 LEU B CD2 1 ATOM 4677 N N . ASN B 1 176 ? -55.244 26.927 11.739 1.00 16.88 ? 209 ASN B N 1 ATOM 4678 C CA . ASN B 1 176 ? -56.398 27.559 11.107 1.00 16.99 ? 209 ASN B CA 1 ATOM 4679 C C . ASN B 1 176 ? -57.574 27.546 12.085 1.00 17.30 ? 209 ASN B C 1 ATOM 4680 O O . ASN B 1 176 ? -58.589 26.805 11.916 1.00 16.84 ? 209 ASN B O 1 ATOM 4681 C CB . ASN B 1 176 ? -56.813 26.844 9.826 1.00 16.85 ? 209 ASN B CB 1 ATOM 4682 C CG . ASN B 1 176 ? -57.713 27.697 9.004 1.00 17.69 ? 209 ASN B CG 1 ATOM 4683 O OD1 . ASN B 1 176 ? -58.203 28.703 9.496 1.00 16.18 ? 209 ASN B OD1 1 ATOM 4684 N ND2 . ASN B 1 176 ? -57.903 27.344 7.726 1.00 19.80 ? 209 ASN B ND2 1 ATOM 4685 N N . THR B 1 177 ? -57.435 28.408 13.092 1.00 17.25 ? 210 THR B N 1 ATOM 4686 C CA . THR B 1 177 ? -58.484 28.603 14.098 1.00 16.83 ? 210 THR B CA 1 ATOM 4687 C C . THR B 1 177 ? -59.710 29.358 13.536 1.00 16.69 ? 210 THR B C 1 ATOM 4688 O O . THR B 1 177 ? -60.752 29.399 14.183 1.00 16.06 ? 210 THR B O 1 ATOM 4689 C CB . THR B 1 177 ? -57.938 29.292 15.362 1.00 16.20 ? 210 THR B CB 1 ATOM 4690 O OG1 . THR B 1 177 ? -57.226 30.489 14.997 1.00 16.29 ? 210 THR B OG1 1 ATOM 4691 C CG2 . THR B 1 177 ? -57.040 28.324 16.106 1.00 15.52 ? 210 THR B CG2 1 ATOM 4692 N N . ASN B 1 178 ? -59.594 29.908 12.326 1.00 16.18 ? 211 ASN B N 1 ATOM 4693 C CA . ASN B 1 178 ? -60.763 30.398 11.596 1.00 16.66 ? 211 ASN B CA 1 ATOM 4694 C C . ASN B 1 178 ? -61.871 29.314 11.455 1.00 16.48 ? 211 ASN B C 1 ATOM 4695 O O . ASN B 1 178 ? -63.083 29.578 11.641 1.00 15.73 ? 211 ASN B O 1 ATOM 4696 C CB . ASN B 1 178 ? -60.309 30.965 10.211 1.00 16.90 ? 211 ASN B CB 1 ATOM 4697 C CG . ASN B 1 178 ? -59.235 32.057 10.352 1.00 16.57 ? 211 ASN B CG 1 ATOM 4698 O OD1 . ASN B 1 178 ? -58.062 31.860 10.069 1.00 15.86 ? 211 ASN B OD1 1 ATOM 4699 N ND2 . ASN B 1 178 ? -59.637 33.177 10.875 1.00 16.79 ? 211 ASN B ND2 1 ATOM 4700 N N . LEU B 1 179 ? -61.430 28.096 11.160 1.00 16.83 ? 212 LEU B N 1 ATOM 4701 C CA . LEU B 1 179 ? -62.283 26.930 11.211 1.00 17.46 ? 212 LEU B CA 1 ATOM 4702 C C . LEU B 1 179 ? -63.177 26.989 12.411 1.00 16.47 ? 212 LEU B C 1 ATOM 4703 O O . LEU B 1 179 ? -64.219 26.491 12.363 1.00 15.77 ? 212 LEU B O 1 ATOM 4704 C CB . LEU B 1 179 ? -61.449 25.632 11.330 1.00 18.90 ? 212 LEU B CB 1 ATOM 4705 C CG . LEU B 1 179 ? -60.616 25.454 10.077 1.00 22.02 ? 212 LEU B CG 1 ATOM 4706 C CD1 . LEU B 1 179 ? -59.784 24.160 10.128 1.00 22.60 ? 212 LEU B CD1 1 ATOM 4707 C CD2 . LEU B 1 179 ? -61.556 25.500 8.846 1.00 20.85 ? 212 LEU B CD2 1 ATOM 4708 N N . TYR B 1 180 ? -62.719 27.551 13.509 1.00 17.88 ? 213 TYR B N 1 ATOM 4709 C CA . TYR B 1 180 ? -63.437 27.531 14.788 1.00 19.72 ? 213 TYR B CA 1 ATOM 4710 C C . TYR B 1 180 ? -64.258 28.809 15.120 1.00 18.18 ? 213 TYR B C 1 ATOM 4711 O O . TYR B 1 180 ? -65.044 28.793 16.053 1.00 16.32 ? 213 TYR B O 1 ATOM 4712 C CB . TYR B 1 180 ? -62.422 27.194 15.965 1.00 21.67 ? 213 TYR B CB 1 ATOM 4713 C CG . TYR B 1 180 ? -61.548 25.964 15.729 1.00 20.31 ? 213 TYR B CG 1 ATOM 4714 C CD1 . TYR B 1 180 ? -62.102 24.776 15.295 1.00 21.77 ? 213 TYR B CD1 1 ATOM 4715 C CD2 . TYR B 1 180 ? -60.203 25.989 15.970 1.00 20.83 ? 213 TYR B CD2 1 ATOM 4716 C CE1 . TYR B 1 180 ? -61.321 23.644 15.085 1.00 22.44 ? 213 TYR B CE1 1 ATOM 4717 C CE2 . TYR B 1 180 ? -59.394 24.880 15.737 1.00 21.15 ? 213 TYR B CE2 1 ATOM 4718 C CZ . TYR B 1 180 ? -59.956 23.706 15.305 1.00 22.19 ? 213 TYR B CZ 1 ATOM 4719 O OH . TYR B 1 180 ? -59.193 22.577 15.056 1.00 23.05 ? 213 TYR B OH 1 ATOM 4720 N N . TYR B 1 181 ? -64.088 29.870 14.316 1.00 19.70 ? 214 TYR B N 1 ATOM 4721 C CA . TYR B 1 181 ? -64.702 31.237 14.528 1.00 21.58 ? 214 TYR B CA 1 ATOM 4722 C C . TYR B 1 181 ? -66.173 31.174 14.328 1.00 24.21 ? 214 TYR B C 1 ATOM 4723 O O . TYR B 1 181 ? -66.631 30.624 13.306 1.00 29.39 ? 214 TYR B O 1 ATOM 4724 C CB . TYR B 1 181 ? -64.073 32.210 13.541 1.00 21.91 ? 214 TYR B CB 1 ATOM 4725 C CG . TYR B 1 181 ? -64.365 33.692 13.627 1.00 21.51 ? 214 TYR B CG 1 ATOM 4726 C CD1 . TYR B 1 181 ? -64.434 34.382 14.814 1.00 22.52 ? 214 TYR B CD1 1 ATOM 4727 C CD2 . TYR B 1 181 ? -64.498 34.410 12.450 1.00 24.56 ? 214 TYR B CD2 1 ATOM 4728 C CE1 . TYR B 1 181 ? -64.668 35.752 14.822 1.00 23.76 ? 214 TYR B CE1 1 ATOM 4729 C CE2 . TYR B 1 181 ? -64.746 35.750 12.419 1.00 23.55 ? 214 TYR B CE2 1 ATOM 4730 C CZ . TYR B 1 181 ? -64.813 36.419 13.585 1.00 25.43 ? 214 TYR B CZ 1 ATOM 4731 O OH . TYR B 1 181 ? -65.031 37.766 13.416 1.00 30.62 ? 214 TYR B OH 1 ATOM 4732 N N . GLY B 1 182 ? -66.902 31.753 15.297 1.00 26.47 ? 215 GLY B N 1 ATOM 4733 C CA . GLY B 1 182 ? -68.403 31.822 15.347 1.00 26.36 ? 215 GLY B CA 1 ATOM 4734 C C . GLY B 1 182 ? -69.046 31.963 13.977 1.00 24.78 ? 215 GLY B C 1 ATOM 4735 O O . GLY B 1 182 ? -69.675 31.045 13.510 1.00 24.25 ? 215 GLY B O 1 ATOM 4736 N N . PRO B 1 183 ? -68.787 33.071 13.282 1.00 25.55 ? 216 PRO B N 1 ATOM 4737 C CA . PRO B 1 183 ? -69.395 33.264 11.966 1.00 26.50 ? 216 PRO B CA 1 ATOM 4738 C C . PRO B 1 183 ? -69.029 32.288 10.839 1.00 28.56 ? 216 PRO B C 1 ATOM 4739 O O . PRO B 1 183 ? -69.559 32.482 9.717 1.00 33.44 ? 216 PRO B O 1 ATOM 4740 C CB . PRO B 1 183 ? -68.999 34.720 11.564 1.00 26.18 ? 216 PRO B CB 1 ATOM 4741 C CG . PRO B 1 183 ? -68.156 35.280 12.675 1.00 26.40 ? 216 PRO B CG 1 ATOM 4742 C CD . PRO B 1 183 ? -67.893 34.184 13.682 1.00 26.65 ? 216 PRO B CD 1 ATOM 4743 N N . ASN B 1 184 ? -68.173 31.281 11.067 1.00 27.45 ? 217 ASN B N 1 ATOM 4744 C CA . ASN B 1 184 ? -67.919 30.270 9.991 1.00 28.28 ? 217 ASN B CA 1 ATOM 4745 C C . ASN B 1 184 ? -69.032 29.136 9.784 1.00 28.51 ? 217 ASN B C 1 ATOM 4746 O O . ASN B 1 184 ? -69.115 28.113 10.541 1.00 22.63 ? 217 ASN B O 1 ATOM 4747 C CB . ASN B 1 184 ? -66.502 29.667 10.103 1.00 27.74 ? 217 ASN B CB 1 ATOM 4748 C CG . ASN B 1 184 ? -66.106 28.871 8.845 1.00 26.48 ? 217 ASN B CG 1 ATOM 4749 O OD1 . ASN B 1 184 ? -66.893 28.704 7.926 1.00 23.65 ? 217 ASN B OD1 1 ATOM 4750 N ND2 . ASN B 1 184 ? -64.871 28.396 8.808 1.00 27.98 ? 217 ASN B ND2 1 ATOM 4751 N N . ILE B 1 185 ? -69.830 29.338 8.720 1.00 28.16 ? 218 ILE B N 1 ATOM 4752 C CA . ILE B 1 185 ? -70.974 28.438 8.359 1.00 32.01 ? 218 ILE B CA 1 ATOM 4753 C C . ILE B 1 185 ? -70.497 27.097 7.810 1.00 31.53 ? 218 ILE B C 1 ATOM 4754 O O . ILE B 1 185 ? -71.249 26.121 7.846 1.00 30.76 ? 218 ILE B O 1 ATOM 4755 C CB . ILE B 1 185 ? -71.939 29.075 7.289 1.00 32.35 ? 218 ILE B CB 1 ATOM 4756 C CG1 . ILE B 1 185 ? -72.386 30.509 7.697 1.00 33.18 ? 218 ILE B CG1 1 ATOM 4757 C CG2 . ILE B 1 185 ? -73.147 28.201 6.986 1.00 30.31 ? 218 ILE B CG2 1 ATOM 4758 C CD1 . ILE B 1 185 ? -72.461 30.795 9.186 1.00 33.85 ? 218 ILE B CD1 1 ATOM 4759 N N . MET B 1 186 ? -69.259 27.060 7.304 1.00 31.67 ? 219 MET B N 1 ATOM 4760 C CA . MET B 1 186 ? -68.698 25.871 6.654 1.00 31.62 ? 219 MET B CA 1 ATOM 4761 C C . MET B 1 186 ? -68.401 24.754 7.653 1.00 32.85 ? 219 MET B C 1 ATOM 4762 O O . MET B 1 186 ? -68.438 23.552 7.298 1.00 32.73 ? 219 MET B O 1 ATOM 4763 C CB . MET B 1 186 ? -67.434 26.233 5.870 1.00 34.58 ? 219 MET B CB 1 ATOM 4764 C CG . MET B 1 186 ? -67.657 27.244 4.732 1.00 37.88 ? 219 MET B CG 1 ATOM 4765 S SD . MET B 1 186 ? -68.536 26.562 3.283 1.00 40.42 ? 219 MET B SD 1 ATOM 4766 C CE . MET B 1 186 ? -70.176 27.116 3.756 1.00 36.94 ? 219 MET B CE 1 ATOM 4767 N N . THR B 1 187 ? -68.149 25.131 8.913 1.00 33.43 ? 220 THR B N 1 ATOM 4768 C CA . THR B 1 187 ? -67.771 24.144 9.928 1.00 31.08 ? 220 THR B CA 1 ATOM 4769 C C . THR B 1 187 ? -68.912 23.835 10.893 1.00 30.90 ? 220 THR B C 1 ATOM 4770 O O . THR B 1 187 ? -68.762 23.041 11.807 1.00 30.87 ? 220 THR B O 1 ATOM 4771 C CB . THR B 1 187 ? -66.497 24.587 10.668 1.00 30.52 ? 220 THR B CB 1 ATOM 4772 O OG1 . THR B 1 187 ? -66.762 25.764 11.469 1.00 29.44 ? 220 THR B OG1 1 ATOM 4773 C CG2 . THR B 1 187 ? -65.404 24.872 9.632 1.00 29.95 ? 220 THR B CG2 1 ATOM 4774 N N . LEU B 1 188 ? -70.067 24.440 10.697 1.00 33.42 ? 221 LEU B N 1 ATOM 4775 C CA . LEU B 1 188 ? -71.155 24.150 11.617 1.00 35.88 ? 221 LEU B CA 1 ATOM 4776 C C . LEU B 1 188 ? -71.337 22.667 11.695 1.00 36.06 ? 221 LEU B C 1 ATOM 4777 O O . LEU B 1 188 ? -71.308 21.964 10.665 1.00 34.68 ? 221 LEU B O 1 ATOM 4778 C CB . LEU B 1 188 ? -72.470 24.822 11.210 1.00 37.14 ? 221 LEU B CB 1 ATOM 4779 C CG . LEU B 1 188 ? -72.598 26.131 11.958 1.00 38.66 ? 221 LEU B CG 1 ATOM 4780 C CD1 . LEU B 1 188 ? -73.701 26.960 11.340 1.00 42.22 ? 221 LEU B CD1 1 ATOM 4781 C CD2 . LEU B 1 188 ? -72.837 25.898 13.451 1.00 38.38 ? 221 LEU B CD2 1 ATOM 4782 N N . ASN B 1 189 ? -71.466 22.217 12.938 1.00 39.04 ? 222 ASN B N 1 ATOM 4783 C CA . ASN B 1 189 ? -71.776 20.836 13.293 1.00 43.20 ? 222 ASN B CA 1 ATOM 4784 C C . ASN B 1 189 ? -70.675 19.791 13.034 1.00 40.92 ? 222 ASN B C 1 ATOM 4785 O O . ASN B 1 189 ? -70.931 18.585 13.134 1.00 46.69 ? 222 ASN B O 1 ATOM 4786 C CB . ASN B 1 189 ? -73.098 20.410 12.626 1.00 47.35 ? 222 ASN B CB 1 ATOM 4787 C CG . ASN B 1 189 ? -73.887 19.474 13.495 1.00 51.95 ? 222 ASN B CG 1 ATOM 4788 O OD1 . ASN B 1 189 ? -74.034 19.728 14.686 1.00 51.68 ? 222 ASN B OD1 1 ATOM 4789 N ND2 . ASN B 1 189 ? -74.357 18.359 12.924 1.00 58.39 ? 222 ASN B ND2 1 ATOM 4790 N N . LYS B 1 190 ? -69.457 20.245 12.718 1.00 40.27 ? 223 LYS B N 1 ATOM 4791 C CA . LYS B 1 190 ? -68.287 19.344 12.512 1.00 35.08 ? 223 LYS B CA 1 ATOM 4792 C C . LYS B 1 190 ? -67.506 19.151 13.825 1.00 30.12 ? 223 LYS B C 1 ATOM 4793 O O . LYS B 1 190 ? -67.215 20.105 14.556 1.00 24.56 ? 223 LYS B O 1 ATOM 4794 C CB . LYS B 1 190 ? -67.382 19.837 11.368 1.00 33.52 ? 223 LYS B CB 1 ATOM 4795 C CG . LYS B 1 190 ? -67.831 19.393 9.993 1.00 33.64 ? 223 LYS B CG 1 ATOM 4796 C CD . LYS B 1 190 ? -67.156 20.174 8.879 1.00 37.55 ? 223 LYS B CD 1 ATOM 4797 C CE . LYS B 1 190 ? -67.838 19.923 7.529 1.00 46.22 ? 223 LYS B CE 1 ATOM 4798 N NZ . LYS B 1 190 ? -67.667 20.974 6.435 1.00 53.38 1 223 LYS B NZ 1 ATOM 4799 N N . THR B 1 191 ? -67.218 17.889 14.119 1.00 31.34 ? 224 THR B N 1 ATOM 4800 C CA . THR B 1 191 ? -66.534 17.516 15.363 1.00 32.84 ? 224 THR B CA 1 ATOM 4801 C C . THR B 1 191 ? -65.018 17.829 15.317 1.00 28.12 ? 224 THR B C 1 ATOM 4802 O O . THR B 1 191 ? -64.424 18.233 16.296 1.00 29.24 ? 224 THR B O 1 ATOM 4803 C CB . THR B 1 191 ? -66.767 16.027 15.726 1.00 36.29 ? 224 THR B CB 1 ATOM 4804 O OG1 . THR B 1 191 ? -66.140 15.752 16.982 1.00 40.58 ? 224 THR B OG1 1 ATOM 4805 C CG2 . THR B 1 191 ? -66.198 15.048 14.645 1.00 39.00 ? 224 THR B CG2 1 ATOM 4806 N N . ASP B 1 192 ? -64.407 17.650 14.169 1.00 25.06 ? 225 ASP B N 1 ATOM 4807 C CA . ASP B 1 192 ? -63.005 17.950 14.010 1.00 23.99 ? 225 ASP B CA 1 ATOM 4808 C C . ASP B 1 192 ? -62.769 18.522 12.572 1.00 21.77 ? 225 ASP B C 1 ATOM 4809 O O . ASP B 1 192 ? -62.308 17.790 11.701 1.00 19.66 ? 225 ASP B O 1 ATOM 4810 C CB . ASP B 1 192 ? -62.185 16.687 14.299 1.00 24.51 ? 225 ASP B CB 1 ATOM 4811 C CG . ASP B 1 192 ? -60.695 16.905 14.134 1.00 27.98 ? 225 ASP B CG 1 ATOM 4812 O OD1 . ASP B 1 192 ? -60.291 18.011 13.742 1.00 30.06 ? 225 ASP B OD1 1 ATOM 4813 O OD2 . ASP B 1 192 ? -59.902 15.973 14.376 1.00 31.89 -1 225 ASP B OD2 1 ATOM 4814 N N . PRO B 1 193 ? -63.120 19.821 12.338 1.00 19.25 ? 226 PRO B N 1 ATOM 4815 C CA . PRO B 1 193 ? -63.001 20.433 11.020 1.00 19.34 ? 226 PRO B CA 1 ATOM 4816 C C . PRO B 1 193 ? -61.595 20.401 10.453 1.00 18.96 ? 226 PRO B C 1 ATOM 4817 O O . PRO B 1 193 ? -60.633 20.742 11.156 1.00 16.60 ? 226 PRO B O 1 ATOM 4818 C CB . PRO B 1 193 ? -63.420 21.882 11.242 1.00 19.40 ? 226 PRO B CB 1 ATOM 4819 C CG . PRO B 1 193 ? -63.403 22.049 12.712 1.00 19.60 ? 226 PRO B CG 1 ATOM 4820 C CD . PRO B 1 193 ? -63.756 20.744 13.285 1.00 18.49 ? 226 PRO B CD 1 ATOM 4821 N N . ALA B 1 194 ? -61.528 19.918 9.213 1.00 18.24 ? 227 ALA B N 1 ATOM 4822 C CA . ALA B 1 194 ? -60.305 19.692 8.484 1.00 19.38 ? 227 ALA B CA 1 ATOM 4823 C C . ALA B 1 194 ? -59.337 18.660 9.164 1.00 20.41 ? 227 ALA B C 1 ATOM 4824 O O . ALA B 1 194 ? -58.229 18.462 8.706 1.00 21.37 ? 227 ALA B O 1 ATOM 4825 C CB . ALA B 1 194 ? -59.629 21.028 8.134 1.00 19.13 ? 227 ALA B CB 1 ATOM 4826 N N . ASN B 1 195 ? -59.811 17.932 10.167 1.00 21.81 ? 228 ASN B N 1 ATOM 4827 C CA . ASN B 1 195 ? -58.992 17.007 10.957 1.00 25.03 ? 228 ASN B CA 1 ATOM 4828 C C . ASN B 1 195 ? -57.890 17.668 11.832 1.00 23.72 ? 228 ASN B C 1 ATOM 4829 O O . ASN B 1 195 ? -56.919 17.014 12.335 1.00 21.17 ? 228 ASN B O 1 ATOM 4830 C CB . ASN B 1 195 ? -58.432 15.885 10.065 1.00 29.03 ? 228 ASN B CB 1 ATOM 4831 C CG . ASN B 1 195 ? -59.290 14.649 10.137 1.00 34.50 ? 228 ASN B CG 1 ATOM 4832 O OD1 . ASN B 1 195 ? -60.111 14.394 9.261 1.00 36.49 ? 228 ASN B OD1 1 ATOM 4833 N ND2 . ASN B 1 195 ? -59.170 13.913 11.249 1.00 39.74 ? 228 ASN B ND2 1 ATOM 4834 N N . GLN B 1 196 ? -58.076 18.960 12.053 1.00 20.06 ? 229 GLN B N 1 ATOM 4835 C CA . GLN B 1 196 ? -57.041 19.725 12.697 1.00 19.25 ? 229 GLN B CA 1 ATOM 4836 C C . GLN B 1 196 ? -56.771 19.208 14.083 1.00 19.41 ? 229 GLN B C 1 ATOM 4837 O O . GLN B 1 196 ? -55.625 19.239 14.484 1.00 21.06 ? 229 GLN B O 1 ATOM 4838 C CB . GLN B 1 196 ? -57.341 21.280 12.710 1.00 17.65 ? 229 GLN B CB 1 ATOM 4839 C CG . GLN B 1 196 ? -56.079 22.138 12.658 1.00 14.91 ? 229 GLN B CG 1 ATOM 4840 C CD . GLN B 1 196 ? -56.266 23.622 12.560 1.00 12.74 ? 229 GLN B CD 1 ATOM 4841 O OE1 . GLN B 1 196 ? -57.180 24.206 13.068 1.00 11.95 ? 229 GLN B OE1 1 ATOM 4842 N NE2 . GLN B 1 196 ? -55.344 24.233 11.953 1.00 11.77 ? 229 GLN B NE2 1 ATOM 4843 N N . PHE B 1 197 ? -57.800 18.789 14.816 1.00 19.59 ? 230 PHE B N 1 ATOM 4844 C CA . PHE B 1 197 ? -57.611 18.298 16.174 1.00 21.97 ? 230 PHE B CA 1 ATOM 4845 C C . PHE B 1 197 ? -56.753 17.057 16.246 1.00 26.18 ? 230 PHE B C 1 ATOM 4846 O O . PHE B 1 197 ? -55.934 16.916 17.166 1.00 28.17 ? 230 PHE B O 1 ATOM 4847 C CB . PHE B 1 197 ? -58.915 17.973 16.853 1.00 20.29 ? 230 PHE B CB 1 ATOM 4848 C CG . PHE B 1 197 ? -59.726 19.171 17.152 1.00 20.52 ? 230 PHE B CG 1 ATOM 4849 C CD1 . PHE B 1 197 ? -59.168 20.254 17.789 1.00 19.87 ? 230 PHE B CD1 1 ATOM 4850 C CD2 . PHE B 1 197 ? -61.033 19.221 16.822 1.00 20.91 ? 230 PHE B CD2 1 ATOM 4851 C CE1 . PHE B 1 197 ? -59.910 21.348 18.077 1.00 18.40 ? 230 PHE B CE1 1 ATOM 4852 C CE2 . PHE B 1 197 ? -61.792 20.320 17.117 1.00 20.90 ? 230 PHE B CE2 1 ATOM 4853 C CZ . PHE B 1 197 ? -61.220 21.387 17.723 1.00 19.97 ? 230 PHE B CZ 1 ATOM 4854 N N . GLU B 1 198 ? -56.988 16.141 15.313 1.00 29.40 ? 231 GLU B N 1 ATOM 4855 C CA . GLU B 1 198 ? -56.288 14.861 15.282 1.00 30.79 ? 231 GLU B CA 1 ATOM 4856 C C . GLU B 1 198 ? -54.831 15.075 14.905 1.00 26.73 ? 231 GLU B C 1 ATOM 4857 O O . GLU B 1 198 ? -53.933 14.594 15.581 1.00 23.34 ? 231 GLU B O 1 ATOM 4858 C CB . GLU B 1 198 ? -56.960 13.910 14.284 1.00 35.35 ? 231 GLU B CB 1 ATOM 4859 C CG . GLU B 1 198 ? -56.476 12.473 14.397 1.00 41.93 ? 231 GLU B CG 1 ATOM 4860 C CD . GLU B 1 198 ? -57.124 11.562 13.374 1.00 51.60 ? 231 GLU B CD 1 ATOM 4861 O OE1 . GLU B 1 198 ? -58.376 11.616 13.211 1.00 55.95 ? 231 GLU B OE1 1 ATOM 4862 O OE2 . GLU B 1 198 ? -56.370 10.794 12.736 1.00 56.13 -1 231 GLU B OE2 1 ATOM 4863 N N . TRP B 1 199 ? -54.638 15.801 13.814 1.00 24.72 ? 232 TRP B N 1 ATOM 4864 C CA . TRP B 1 199 ? -53.323 16.208 13.365 1.00 25.39 ? 232 TRP B CA 1 ATOM 4865 C C . TRP B 1 199 ? -52.504 16.981 14.392 1.00 25.09 ? 232 TRP B C 1 ATOM 4866 O O . TRP B 1 199 ? -51.285 16.780 14.469 1.00 23.96 ? 232 TRP B O 1 ATOM 4867 C CB . TRP B 1 199 ? -53.472 17.084 12.147 1.00 24.18 ? 232 TRP B CB 1 ATOM 4868 C CG . TRP B 1 199 ? -52.206 17.723 11.603 1.00 26.09 ? 232 TRP B CG 1 ATOM 4869 C CD1 . TRP B 1 199 ? -51.381 17.209 10.637 1.00 25.96 ? 232 TRP B CD1 1 ATOM 4870 C CD2 . TRP B 1 199 ? -51.676 19.042 11.920 1.00 25.19 ? 232 TRP B CD2 1 ATOM 4871 N NE1 . TRP B 1 199 ? -50.404 18.129 10.320 1.00 27.27 ? 232 TRP B NE1 1 ATOM 4872 C CE2 . TRP B 1 199 ? -50.562 19.253 11.090 1.00 24.71 ? 232 TRP B CE2 1 ATOM 4873 C CE3 . TRP B 1 199 ? -52.090 20.077 12.762 1.00 25.06 ? 232 TRP B CE3 1 ATOM 4874 C CZ2 . TRP B 1 199 ? -49.836 20.419 11.109 1.00 24.19 ? 232 TRP B CZ2 1 ATOM 4875 C CZ3 . TRP B 1 199 ? -51.364 21.232 12.774 1.00 25.56 ? 232 TRP B CZ3 1 ATOM 4876 C CH2 . TRP B 1 199 ? -50.235 21.383 11.983 1.00 24.95 ? 232 TRP B CH2 1 ATOM 4877 N N . LEU B 1 200 ? -53.165 17.871 15.141 1.00 24.31 ? 233 LEU B N 1 ATOM 4878 C CA . LEU B 1 200 ? -52.483 18.738 16.123 1.00 24.51 ? 233 LEU B CA 1 ATOM 4879 C C . LEU B 1 200 ? -51.924 17.918 17.321 1.00 21.59 ? 233 LEU B C 1 ATOM 4880 O O . LEU B 1 200 ? -50.772 18.048 17.683 1.00 17.28 ? 233 LEU B O 1 ATOM 4881 C CB . LEU B 1 200 ? -53.428 19.881 16.595 1.00 24.63 ? 233 LEU B CB 1 ATOM 4882 C CG . LEU B 1 200 ? -52.936 20.715 17.775 1.00 24.71 ? 233 LEU B CG 1 ATOM 4883 C CD1 . LEU B 1 200 ? -51.688 21.487 17.404 1.00 26.40 ? 233 LEU B CD1 1 ATOM 4884 C CD2 . LEU B 1 200 ? -53.999 21.666 18.216 1.00 25.37 ? 233 LEU B CD2 1 ATOM 4885 N N . GLU B 1 201 ? -52.787 17.108 17.914 1.00 22.53 ? 234 GLU B N 1 ATOM 4886 C CA . GLU B 1 201 ? -52.385 16.099 18.891 1.00 25.49 ? 234 GLU B CA 1 ATOM 4887 C C . GLU B 1 201 ? -51.272 15.183 18.373 1.00 26.19 ? 234 GLU B C 1 ATOM 4888 O O . GLU B 1 201 ? -50.301 14.905 19.051 1.00 29.45 ? 234 GLU B O 1 ATOM 4889 C CB . GLU B 1 201 ? -53.567 15.212 19.242 1.00 26.25 ? 234 GLU B CB 1 ATOM 4890 C CG . GLU B 1 201 ? -54.497 15.822 20.258 1.00 30.06 ? 234 GLU B CG 1 ATOM 4891 C CD . GLU B 1 201 ? -54.928 14.844 21.339 1.00 34.30 ? 234 GLU B CD 1 ATOM 4892 O OE1 . GLU B 1 201 ? -56.145 14.884 21.709 1.00 38.49 ? 234 GLU B OE1 1 ATOM 4893 O OE2 . GLU B 1 201 ? -54.042 14.073 21.833 1.00 34.04 -1 234 GLU B OE2 1 ATOM 4894 N N . SER B 1 202 ? -51.437 14.669 17.180 1.00 25.88 ? 235 SER B N 1 ATOM 4895 C CA . SER B 1 202 ? -50.436 13.798 16.622 1.00 26.66 ? 235 SER B CA 1 ATOM 4896 C C . SER B 1 202 ? -49.050 14.534 16.464 1.00 24.32 ? 235 SER B C 1 ATOM 4897 O O . SER B 1 202 ? -48.000 13.998 16.836 1.00 21.17 ? 235 SER B O 1 ATOM 4898 C CB . SER B 1 202 ? -51.013 13.181 15.333 1.00 27.58 ? 235 SER B CB 1 ATOM 4899 O OG . SER B 1 202 ? -50.012 12.830 14.428 1.00 34.22 ? 235 SER B OG 1 ATOM 4900 N N . THR B 1 203 ? -49.087 15.776 15.982 1.00 22.93 ? 236 THR B N 1 ATOM 4901 C CA . THR B 1 203 ? -47.896 16.620 15.869 1.00 22.96 ? 236 THR B CA 1 ATOM 4902 C C . THR B 1 203 ? -47.240 16.959 17.233 1.00 25.41 ? 236 THR B C 1 ATOM 4903 O O . THR B 1 203 ? -46.017 16.940 17.363 1.00 25.58 ? 236 THR B O 1 ATOM 4904 C CB . THR B 1 203 ? -48.228 17.940 15.181 1.00 20.95 ? 236 THR B CB 1 ATOM 4905 O OG1 . THR B 1 203 ? -48.853 17.694 13.921 1.00 21.19 ? 236 THR B OG1 1 ATOM 4906 C CG2 . THR B 1 203 ? -46.957 18.788 14.965 1.00 21.02 ? 236 THR B CG2 1 ATOM 4907 N N . LEU B 1 204 ? -48.063 17.303 18.223 1.00 28.46 ? 237 LEU B N 1 ATOM 4908 C CA . LEU B 1 204 ? -47.593 17.581 19.581 1.00 30.79 ? 237 LEU B CA 1 ATOM 4909 C C . LEU B 1 204 ? -46.985 16.343 20.190 1.00 32.03 ? 237 LEU B C 1 ATOM 4910 O O . LEU B 1 204 ? -46.004 16.448 20.894 1.00 30.63 ? 237 LEU B O 1 ATOM 4911 C CB . LEU B 1 204 ? -48.720 18.096 20.472 1.00 30.47 ? 237 LEU B CB 1 ATOM 4912 C CG . LEU B 1 204 ? -49.160 19.486 19.964 1.00 35.84 ? 237 LEU B CG 1 ATOM 4913 C CD1 . LEU B 1 204 ? -50.599 19.942 20.325 1.00 33.82 ? 237 LEU B CD1 1 ATOM 4914 C CD2 . LEU B 1 204 ? -48.096 20.497 20.407 1.00 37.39 ? 237 LEU B CD2 1 ATOM 4915 N N . ASN B 1 205 ? -47.567 15.181 19.897 1.00 34.12 ? 238 ASN B N 1 ATOM 4916 C CA . ASN B 1 205 ? -47.082 13.921 20.418 1.00 38.06 ? 238 ASN B CA 1 ATOM 4917 C C . ASN B 1 205 ? -45.716 13.609 19.814 1.00 37.93 ? 238 ASN B C 1 ATOM 4918 O O . ASN B 1 205 ? -44.782 13.243 20.535 1.00 36.29 ? 238 ASN B O 1 ATOM 4919 C CB . ASN B 1 205 ? -48.085 12.785 20.160 1.00 40.16 ? 238 ASN B CB 1 ATOM 4920 C CG . ASN B 1 205 ? -47.963 11.665 21.187 1.00 41.70 ? 238 ASN B CG 1 ATOM 4921 O OD1 . ASN B 1 205 ? -47.407 10.597 20.913 1.00 42.29 ? 238 ASN B OD1 1 ATOM 4922 N ND2 . ASN B 1 205 ? -48.455 11.922 22.387 1.00 41.73 ? 238 ASN B ND2 1 ATOM 4923 N N . ASN B 1 206 ? -45.616 13.796 18.498 1.00 40.88 ? 239 ASN B N 1 ATOM 4924 C CA . ASN B 1 206 ? -44.348 13.736 17.778 1.00 42.71 ? 239 ASN B CA 1 ATOM 4925 C C . ASN B 1 206 ? -43.279 14.669 18.375 1.00 38.13 ? 239 ASN B C 1 ATOM 4926 O O . ASN B 1 206 ? -42.162 14.236 18.626 1.00 35.77 ? 239 ASN B O 1 ATOM 4927 C CB . ASN B 1 206 ? -44.559 14.042 16.285 1.00 49.79 ? 239 ASN B CB 1 ATOM 4928 C CG . ASN B 1 206 ? -43.312 14.658 15.619 1.00 62.15 ? 239 ASN B CG 1 ATOM 4929 O OD1 . ASN B 1 206 ? -43.029 15.877 15.741 1.00 68.02 ? 239 ASN B OD1 1 ATOM 4930 N ND2 . ASN B 1 206 ? -42.578 13.826 14.883 1.00 65.85 ? 239 ASN B ND2 1 ATOM 4931 N N . SER B 1 207 ? -43.615 15.944 18.583 1.00 34.62 ? 240 SER B N 1 ATOM 4932 C CA . SER B 1 207 ? -42.642 16.890 19.106 1.00 33.72 ? 240 SER B CA 1 ATOM 4933 C C . SER B 1 207 ? -42.099 16.430 20.463 1.00 34.23 ? 240 SER B C 1 ATOM 4934 O O . SER B 1 207 ? -40.902 16.485 20.677 1.00 34.98 ? 240 SER B O 1 ATOM 4935 C CB . SER B 1 207 ? -43.219 18.303 19.203 1.00 33.25 ? 240 SER B CB 1 ATOM 4936 O OG . SER B 1 207 ? -43.416 18.860 17.924 1.00 31.56 ? 240 SER B OG 1 ATOM 4937 N N . GLN B 1 208 ? -42.977 15.948 21.335 1.00 35.49 ? 241 GLN B N 1 ATOM 4938 C CA . GLN B 1 208 ? -42.641 15.517 22.689 1.00 40.94 ? 241 GLN B CA 1 ATOM 4939 C C . GLN B 1 208 ? -41.671 14.378 22.694 1.00 46.38 ? 241 GLN B C 1 ATOM 4940 O O . GLN B 1 208 ? -40.852 14.274 23.618 1.00 49.56 ? 241 GLN B O 1 ATOM 4941 C CB . GLN B 1 208 ? -43.886 15.023 23.409 1.00 40.35 ? 241 GLN B CB 1 ATOM 4942 C CG . GLN B 1 208 ? -43.727 14.858 24.893 1.00 42.44 ? 241 GLN B CG 1 ATOM 4943 C CD . GLN B 1 208 ? -45.101 14.848 25.552 1.00 50.65 ? 241 GLN B CD 1 ATOM 4944 O OE1 . GLN B 1 208 ? -45.676 15.906 25.915 1.00 54.91 ? 241 GLN B OE1 1 ATOM 4945 N NE2 . GLN B 1 208 ? -45.680 13.667 25.640 1.00 47.45 ? 241 GLN B NE2 1 ATOM 4946 N N . GLN B 1 209 ? -41.807 13.504 21.693 1.00 46.95 ? 242 GLN B N 1 ATOM 4947 C CA . GLN B 1 209 ? -40.987 12.290 21.588 1.00 49.81 ? 242 GLN B CA 1 ATOM 4948 C C . GLN B 1 209 ? -39.659 12.527 20.875 1.00 46.36 ? 242 GLN B C 1 ATOM 4949 O O . GLN B 1 209 ? -38.747 11.682 20.939 1.00 48.96 ? 242 GLN B O 1 ATOM 4950 C CB . GLN B 1 209 ? -41.771 11.189 20.876 1.00 51.85 ? 242 GLN B CB 1 ATOM 4951 C CG . GLN B 1 209 ? -42.934 10.660 21.694 1.00 56.62 ? 242 GLN B CG 1 ATOM 4952 C CD . GLN B 1 209 ? -43.740 9.619 20.938 1.00 70.95 ? 242 GLN B CD 1 ATOM 4953 O OE1 . GLN B 1 209 ? -43.595 9.455 19.712 1.00 72.82 ? 242 GLN B OE1 1 ATOM 4954 N NE2 . GLN B 1 209 ? -44.607 8.902 21.665 1.00 77.25 ? 242 GLN B NE2 1 ATOM 4955 N N . ASN B 1 210 ? -39.576 13.670 20.193 1.00 38.92 ? 243 ASN B N 1 ATOM 4956 C CA . ASN B 1 210 ? -38.439 14.028 19.386 1.00 34.71 ? 243 ASN B CA 1 ATOM 4957 C C . ASN B 1 210 ? -37.675 15.226 19.897 1.00 34.48 ? 243 ASN B C 1 ATOM 4958 O O . ASN B 1 210 ? -37.013 15.911 19.105 1.00 34.23 ? 243 ASN B O 1 ATOM 4959 C CB . ASN B 1 210 ? -38.910 14.304 17.987 1.00 36.80 ? 243 ASN B CB 1 ATOM 4960 C CG . ASN B 1 210 ? -39.641 13.127 17.381 1.00 41.53 ? 243 ASN B CG 1 ATOM 4961 O OD1 . ASN B 1 210 ? -39.876 12.094 18.025 1.00 44.81 ? 243 ASN B OD1 1 ATOM 4962 N ND2 . ASN B 1 210 ? -40.024 13.285 16.135 1.00 45.09 ? 243 ASN B ND2 1 ATOM 4963 N N . LYS B 1 211 ? -37.752 15.478 21.211 1.00 32.79 ? 244 LYS B N 1 ATOM 4964 C CA . LYS B 1 211 ? -36.926 16.487 21.868 1.00 32.47 ? 244 LYS B CA 1 ATOM 4965 C C . LYS B 1 211 ? -37.060 17.844 21.170 1.00 30.70 ? 244 LYS B C 1 ATOM 4966 O O . LYS B 1 211 ? -36.077 18.553 20.965 1.00 29.45 ? 244 LYS B O 1 ATOM 4967 C CB . LYS B 1 211 ? -35.460 16.025 21.913 1.00 35.10 ? 244 LYS B CB 1 ATOM 4968 C CG . LYS B 1 211 ? -35.288 14.598 22.448 1.00 39.29 ? 244 LYS B CG 1 ATOM 4969 C CD . LYS B 1 211 ? -33.913 13.992 22.193 1.00 40.95 ? 244 LYS B CD 1 ATOM 4970 C CE . LYS B 1 211 ? -32.795 14.783 22.850 1.00 43.55 ? 244 LYS B CE 1 ATOM 4971 N NZ . LYS B 1 211 ? -31.474 14.176 22.533 1.00 44.76 1 244 LYS B NZ 1 ATOM 4972 N N . GLU B 1 212 ? -38.294 18.162 20.784 1.00 29.80 ? 245 GLU B N 1 ATOM 4973 C CA . GLU B 1 212 ? -38.674 19.456 20.158 1.00 28.87 ? 245 GLU B CA 1 ATOM 4974 C C . GLU B 1 212 ? -39.444 20.368 21.162 1.00 27.90 ? 245 GLU B C 1 ATOM 4975 O O . GLU B 1 212 ? -40.058 19.854 22.118 1.00 32.88 ? 245 GLU B O 1 ATOM 4976 C CB . GLU B 1 212 ? -39.522 19.203 18.901 1.00 27.53 ? 245 GLU B CB 1 ATOM 4977 C CG . GLU B 1 212 ? -38.706 18.939 17.645 1.00 27.75 ? 245 GLU B CG 1 ATOM 4978 C CD . GLU B 1 212 ? -39.473 18.315 16.470 1.00 28.78 ? 245 GLU B CD 1 ATOM 4979 O OE1 . GLU B 1 212 ? -40.703 18.073 16.490 1.00 27.32 ? 245 GLU B OE1 1 ATOM 4980 O OE2 . GLU B 1 212 ? -38.800 18.074 15.461 1.00 31.52 -1 245 GLU B OE2 1 ATOM 4981 N N . LYS B 1 213 ? -39.330 21.692 20.984 1.00 25.34 ? 246 LYS B N 1 ATOM 4982 C CA . LYS B 1 213 ? -40.263 22.694 21.542 1.00 22.92 ? 246 LYS B CA 1 ATOM 4983 C C . LYS B 1 213 ? -41.165 23.186 20.404 1.00 21.26 ? 246 LYS B C 1 ATOM 4984 O O . LYS B 1 213 ? -40.784 23.254 19.177 1.00 18.26 ? 246 LYS B O 1 ATOM 4985 C CB . LYS B 1 213 ? -39.565 23.953 22.100 1.00 21.17 ? 246 LYS B CB 1 ATOM 4986 C CG . LYS B 1 213 ? -38.517 23.745 23.143 1.00 22.70 ? 246 LYS B CG 1 ATOM 4987 C CD . LYS B 1 213 ? -38.967 22.982 24.387 1.00 24.73 ? 246 LYS B CD 1 ATOM 4988 C CE . LYS B 1 213 ? -40.152 23.639 25.073 1.00 24.89 ? 246 LYS B CE 1 ATOM 4989 N NZ . LYS B 1 213 ? -40.505 23.095 26.405 1.00 25.32 1 246 LYS B NZ 1 ATOM 4990 N N . VAL B 1 214 ? -42.326 23.641 20.844 1.00 20.73 ? 247 VAL B N 1 ATOM 4991 C CA . VAL B 1 214 ? -43.341 24.221 19.945 1.00 19.10 ? 247 VAL B CA 1 ATOM 4992 C C . VAL B 1 214 ? -43.787 25.604 20.374 1.00 16.37 ? 247 VAL B C 1 ATOM 4993 O O . VAL B 1 214 ? -44.039 25.893 21.492 1.00 13.85 ? 247 VAL B O 1 ATOM 4994 C CB . VAL B 1 214 ? -44.608 23.339 19.881 1.00 20.32 ? 247 VAL B CB 1 ATOM 4995 C CG1 . VAL B 1 214 ? -45.775 24.117 19.298 1.00 21.45 ? 247 VAL B CG1 1 ATOM 4996 C CG2 . VAL B 1 214 ? -44.396 22.059 19.076 1.00 21.35 ? 247 VAL B CG2 1 ATOM 4997 N N . TYR B 1 215 ? -43.863 26.441 19.385 1.00 17.88 ? 248 TYR B N 1 ATOM 4998 C CA . TYR B 1 215 ? -44.634 27.671 19.371 1.00 17.74 ? 248 TYR B CA 1 ATOM 4999 C C . TYR B 1 215 ? -45.900 27.435 18.478 1.00 17.18 ? 248 TYR B C 1 ATOM 5000 O O . TYR B 1 215 ? -45.802 26.995 17.303 1.00 18.25 ? 248 TYR B O 1 ATOM 5001 C CB . TYR B 1 215 ? -43.770 28.739 18.720 1.00 18.51 ? 248 TYR B CB 1 ATOM 5002 C CG . TYR B 1 215 ? -42.589 29.198 19.535 1.00 17.73 ? 248 TYR B CG 1 ATOM 5003 C CD1 . TYR B 1 215 ? -42.518 28.930 20.913 1.00 16.21 ? 248 TYR B CD1 1 ATOM 5004 C CD2 . TYR B 1 215 ? -41.577 30.005 18.923 1.00 17.40 ? 248 TYR B CD2 1 ATOM 5005 C CE1 . TYR B 1 215 ? -41.476 29.420 21.669 1.00 16.24 ? 248 TYR B CE1 1 ATOM 5006 C CE2 . TYR B 1 215 ? -40.506 30.479 19.670 1.00 16.95 ? 248 TYR B CE2 1 ATOM 5007 C CZ . TYR B 1 215 ? -40.437 30.171 21.040 1.00 16.99 ? 248 TYR B CZ 1 ATOM 5008 O OH . TYR B 1 215 ? -39.394 30.675 21.812 1.00 17.74 ? 248 TYR B OH 1 ATOM 5009 N N . ILE B 1 216 ? -47.071 27.691 19.062 1.00 16.51 ? 249 ILE B N 1 ATOM 5010 C CA . ILE B 1 216 ? -48.395 27.660 18.386 1.00 14.99 ? 249 ILE B CA 1 ATOM 5011 C C . ILE B 1 216 ? -48.629 29.061 17.924 1.00 14.48 ? 249 ILE B C 1 ATOM 5012 O O . ILE B 1 216 ? -48.303 30.047 18.665 1.00 15.60 ? 249 ILE B O 1 ATOM 5013 C CB . ILE B 1 216 ? -49.488 27.327 19.377 1.00 14.09 ? 249 ILE B CB 1 ATOM 5014 C CG1 . ILE B 1 216 ? -49.025 26.121 20.161 1.00 14.26 ? 249 ILE B CG1 1 ATOM 5015 C CG2 . ILE B 1 216 ? -50.838 27.110 18.712 1.00 13.29 ? 249 ILE B CG2 1 ATOM 5016 C CD1 . ILE B 1 216 ? -49.236 24.869 19.349 1.00 15.35 ? 249 ILE B CD1 1 ATOM 5017 N N . ILE B 1 217 ? -49.160 29.156 16.721 1.00 13.75 ? 250 ILE B N 1 ATOM 5018 C CA . ILE B 1 217 ? -49.317 30.445 16.002 1.00 14.10 ? 250 ILE B CA 1 ATOM 5019 C C . ILE B 1 217 ? -50.628 30.364 15.215 1.00 13.69 ? 250 ILE B C 1 ATOM 5020 O O . ILE B 1 217 ? -50.949 29.318 14.611 1.00 12.54 ? 250 ILE B O 1 ATOM 5021 C CB . ILE B 1 217 ? -48.082 30.716 15.159 1.00 15.16 ? 250 ILE B CB 1 ATOM 5022 C CG1 . ILE B 1 217 ? -47.473 31.978 15.580 1.00 16.57 ? 250 ILE B CG1 1 ATOM 5023 C CG2 . ILE B 1 217 ? -48.280 30.780 13.644 1.00 16.09 ? 250 ILE B CG2 1 ATOM 5024 C CD1 . ILE B 1 217 ? -45.982 31.770 15.746 1.00 18.73 ? 250 ILE B CD1 1 ATOM 5025 N N . ALA B 1 218 ? -51.448 31.415 15.282 1.00 12.23 ? 251 ALA B N 1 ATOM 5026 C CA . ALA B 1 218 ? -52.807 31.231 14.760 1.00 10.75 ? 251 ALA B CA 1 ATOM 5027 C C . ALA B 1 218 ? -53.403 32.572 14.729 1.00 9.54 ? 251 ALA B C 1 ATOM 5028 O O . ALA B 1 218 ? -52.777 33.519 15.216 1.00 8.52 ? 251 ALA B O 1 ATOM 5029 C CB . ALA B 1 218 ? -53.608 30.238 15.647 1.00 10.68 ? 251 ALA B CB 1 ATOM 5030 N N . HIS B 1 219 ? -54.587 32.673 14.169 1.00 9.18 ? 252 HIS B N 1 ATOM 5031 C CA . HIS B 1 219 ? -55.162 34.010 14.023 1.00 10.43 ? 252 HIS B CA 1 ATOM 5032 C C . HIS B 1 219 ? -56.233 34.435 15.071 1.00 11.19 ? 252 HIS B C 1 ATOM 5033 O O . HIS B 1 219 ? -56.012 35.260 15.912 1.00 10.30 ? 252 HIS B O 1 ATOM 5034 C CB . HIS B 1 219 ? -55.669 34.184 12.590 1.00 10.30 ? 252 HIS B CB 1 ATOM 5035 C CG . HIS B 1 219 ? -56.215 35.540 12.328 1.00 9.66 ? 252 HIS B CG 1 ATOM 5036 N ND1 . HIS B 1 219 ? -55.398 36.619 12.140 1.00 9.49 ? 252 HIS B ND1 1 ATOM 5037 C CD2 . HIS B 1 219 ? -57.488 35.995 12.259 1.00 9.25 ? 252 HIS B CD2 1 ATOM 5038 C CE1 . HIS B 1 219 ? -56.140 37.685 11.952 1.00 9.29 ? 252 HIS B CE1 1 ATOM 5039 N NE2 . HIS B 1 219 ? -57.408 37.335 12.048 1.00 9.18 ? 252 HIS B NE2 1 ATOM 5040 N N . VAL B 1 220 ? -57.414 33.877 14.978 1.00 13.62 ? 253 VAL B N 1 ATOM 5041 C CA . VAL B 1 220 ? -58.320 33.911 16.092 1.00 16.07 ? 253 VAL B CA 1 ATOM 5042 C C . VAL B 1 220 ? -57.845 33.121 17.317 1.00 15.08 ? 253 VAL B C 1 ATOM 5043 O O . VAL B 1 220 ? -57.605 31.936 17.213 1.00 13.96 ? 253 VAL B O 1 ATOM 5044 C CB . VAL B 1 220 ? -59.649 33.308 15.695 1.00 18.12 ? 253 VAL B CB 1 ATOM 5045 C CG1 . VAL B 1 220 ? -60.496 33.088 16.941 1.00 18.03 ? 253 VAL B CG1 1 ATOM 5046 C CG2 . VAL B 1 220 ? -60.304 34.293 14.725 1.00 19.73 ? 253 VAL B CG2 1 ATOM 5047 N N . PRO B 1 221 ? -57.744 33.802 18.478 1.00 15.47 ? 254 PRO B N 1 ATOM 5048 C CA . PRO B 1 221 ? -57.154 33.184 19.656 1.00 16.81 ? 254 PRO B CA 1 ATOM 5049 C C . PRO B 1 221 ? -58.135 32.404 20.491 1.00 17.27 ? 254 PRO B C 1 ATOM 5050 O O . PRO B 1 221 ? -59.335 32.583 20.366 1.00 16.77 ? 254 PRO B O 1 ATOM 5051 C CB . PRO B 1 221 ? -56.715 34.372 20.470 1.00 16.12 ? 254 PRO B CB 1 ATOM 5052 C CG . PRO B 1 221 ? -57.761 35.413 20.160 1.00 15.10 ? 254 PRO B CG 1 ATOM 5053 C CD . PRO B 1 221 ? -58.003 35.241 18.713 1.00 14.73 ? 254 PRO B CD 1 ATOM 5054 N N . VAL B 1 222 ? -57.611 31.535 21.342 1.00 18.11 ? 255 VAL B N 1 ATOM 5055 C CA . VAL B 1 222 ? -58.470 30.923 22.297 1.00 19.09 ? 255 VAL B CA 1 ATOM 5056 C C . VAL B 1 222 ? -58.929 31.956 23.367 1.00 21.30 ? 255 VAL B C 1 ATOM 5057 O O . VAL B 1 222 ? -58.487 33.138 23.388 1.00 21.39 ? 255 VAL B O 1 ATOM 5058 C CB . VAL B 1 222 ? -57.839 29.678 22.896 1.00 18.34 ? 255 VAL B CB 1 ATOM 5059 C CG1 . VAL B 1 222 ? -57.528 28.666 21.825 1.00 17.43 ? 255 VAL B CG1 1 ATOM 5060 C CG2 . VAL B 1 222 ? -56.617 30.041 23.666 1.00 18.70 ? 255 VAL B CG2 1 ATOM 5061 N N . GLY B 1 223 ? -59.887 31.510 24.196 1.00 23.09 ? 256 GLY B N 1 ATOM 5062 C CA . GLY B 1 223 ? -60.350 32.258 25.388 1.00 22.88 ? 256 GLY B CA 1 ATOM 5063 C C . GLY B 1 223 ? -61.453 33.270 25.092 1.00 21.94 ? 256 GLY B C 1 ATOM 5064 O O . GLY B 1 223 ? -61.957 33.344 24.012 1.00 22.42 ? 256 GLY B O 1 ATOM 5065 N N . TYR B 1 224 ? -61.759 34.079 26.086 1.00 22.79 ? 257 TYR B N 1 ATOM 5066 C CA . TYR B 1 224 ? -62.810 35.053 26.071 1.00 23.02 ? 257 TYR B CA 1 ATOM 5067 C C . TYR B 1 224 ? -62.293 36.426 25.656 1.00 25.54 ? 257 TYR B C 1 ATOM 5068 O O . TYR B 1 224 ? -61.217 36.835 26.082 1.00 24.41 ? 257 TYR B O 1 ATOM 5069 C CB . TYR B 1 224 ? -63.390 35.129 27.478 1.00 22.56 ? 257 TYR B CB 1 ATOM 5070 C CG . TYR B 1 224 ? -64.172 33.948 27.735 1.00 22.86 ? 257 TYR B CG 1 ATOM 5071 C CD1 . TYR B 1 224 ? -63.548 32.760 27.984 1.00 25.38 ? 257 TYR B CD1 1 ATOM 5072 C CD2 . TYR B 1 224 ? -65.545 33.976 27.618 1.00 24.99 ? 257 TYR B CD2 1 ATOM 5073 C CE1 . TYR B 1 224 ? -64.280 31.616 28.173 1.00 29.59 ? 257 TYR B CE1 1 ATOM 5074 C CE2 . TYR B 1 224 ? -66.300 32.838 27.812 1.00 27.24 ? 257 TYR B CE2 1 ATOM 5075 C CZ . TYR B 1 224 ? -65.649 31.660 28.099 1.00 27.42 ? 257 TYR B CZ 1 ATOM 5076 O OH . TYR B 1 224 ? -66.320 30.516 28.279 1.00 26.53 ? 257 TYR B OH 1 ATOM 5077 N N . LEU B 1 225 ? -63.077 37.137 24.831 1.00 30.39 ? 258 LEU B N 1 ATOM 5078 C CA . LEU B 1 225 ? -62.754 38.509 24.419 1.00 32.07 ? 258 LEU B CA 1 ATOM 5079 C C . LEU B 1 225 ? -62.710 39.453 25.635 1.00 35.29 ? 258 LEU B C 1 ATOM 5080 O O . LEU B 1 225 ? -63.606 39.405 26.481 1.00 37.48 ? 258 LEU B O 1 ATOM 5081 C CB . LEU B 1 225 ? -63.723 38.973 23.344 1.00 30.44 ? 258 LEU B CB 1 ATOM 5082 C CG . LEU B 1 225 ? -63.423 38.152 22.051 1.00 34.23 ? 258 LEU B CG 1 ATOM 5083 C CD1 . LEU B 1 225 ? -64.532 38.434 21.019 1.00 35.37 ? 258 LEU B CD1 1 ATOM 5084 C CD2 . LEU B 1 225 ? -61.982 38.225 21.426 1.00 29.59 ? 258 LEU B CD2 1 ATOM 5085 N N . PRO B 1 226 ? -61.631 40.276 25.763 1.00 39.45 ? 259 PRO B N 1 ATOM 5086 C CA . PRO B 1 226 ? -61.488 40.946 27.051 1.00 39.66 ? 259 PRO B CA 1 ATOM 5087 C C . PRO B 1 226 ? -62.359 42.204 27.238 1.00 39.63 ? 259 PRO B C 1 ATOM 5088 O O . PRO B 1 226 ? -62.309 42.791 28.325 1.00 36.36 ? 259 PRO B O 1 ATOM 5089 C CB . PRO B 1 226 ? -59.962 41.265 27.119 1.00 38.54 ? 259 PRO B CB 1 ATOM 5090 C CG . PRO B 1 226 ? -59.316 40.725 25.887 1.00 37.67 ? 259 PRO B CG 1 ATOM 5091 C CD . PRO B 1 226 ? -60.460 40.573 24.901 1.00 41.75 ? 259 PRO B CD 1 ATOM 5092 N N A SER B 1 227 ? -63.124 42.635 26.225 0.50 41.97 ? 260 SER B N 1 ATOM 5093 N N B SER B 1 227 ? -63.138 42.514 26.190 0.50 40.35 ? 260 SER B N 1 ATOM 5094 C CA A SER B 1 227 ? -64.070 43.779 26.377 0.50 44.16 ? 260 SER B CA 1 ATOM 5095 C CA B SER B 1 227 ? -64.048 43.660 26.066 0.50 41.22 ? 260 SER B CA 1 ATOM 5096 C C A SER B 1 227 ? -65.575 43.404 26.302 0.50 45.44 ? 260 SER B C 1 ATOM 5097 C C B SER B 1 227 ? -65.501 43.406 26.558 0.50 43.64 ? 260 SER B C 1 ATOM 5098 O O A SER B 1 227 ? -66.409 44.248 25.955 0.50 46.26 ? 260 SER B O 1 ATOM 5099 O O B SER B 1 227 ? -66.204 44.333 26.958 0.50 44.83 ? 260 SER B O 1 ATOM 5100 C CB A SER B 1 227 ? -63.760 44.911 25.368 0.50 44.30 ? 260 SER B CB 1 ATOM 5101 C CB B SER B 1 227 ? -64.066 44.095 24.580 0.50 40.02 ? 260 SER B CB 1 ATOM 5102 O OG A SER B 1 227 ? -62.831 45.860 25.888 0.50 42.45 ? 260 SER B OG 1 ATOM 5103 O OG B SER B 1 227 ? -63.825 42.996 23.688 0.50 33.45 ? 260 SER B OG 1 ATOM 5104 N N . SER B 1 228 ? -65.921 42.145 26.577 1.00 47.10 ? 261 SER B N 1 ATOM 5105 C CA . SER B 1 228 ? -67.344 41.766 26.827 1.00 51.55 ? 261 SER B CA 1 ATOM 5106 C C . SER B 1 228 ? -67.423 40.514 27.713 1.00 54.46 ? 261 SER B C 1 ATOM 5107 O O . SER B 1 228 ? -66.375 39.975 28.099 1.00 59.72 ? 261 SER B O 1 ATOM 5108 C CB . SER B 1 228 ? -68.103 41.568 25.503 1.00 51.97 ? 261 SER B CB 1 ATOM 5109 O OG . SER B 1 228 ? -67.234 41.210 24.439 1.00 53.24 ? 261 SER B OG 1 ATOM 5110 N N . GLN B 1 229 ? -68.636 40.055 28.047 1.00 54.26 ? 262 GLN B N 1 ATOM 5111 C CA . GLN B 1 229 ? -68.807 38.887 28.966 1.00 56.42 ? 262 GLN B CA 1 ATOM 5112 C C . GLN B 1 229 ? -69.372 37.642 28.277 1.00 50.67 ? 262 GLN B C 1 ATOM 5113 O O . GLN B 1 229 ? -70.250 37.730 27.417 1.00 48.87 ? 262 GLN B O 1 ATOM 5114 C CB . GLN B 1 229 ? -69.657 39.250 30.217 1.00 63.60 ? 262 GLN B CB 1 ATOM 5115 C CG . GLN B 1 229 ? -71.142 38.843 30.195 1.00 67.14 ? 262 GLN B CG 1 ATOM 5116 C CD . GLN B 1 229 ? -71.942 39.308 31.422 1.00 69.38 ? 262 GLN B CD 1 ATOM 5117 O OE1 . GLN B 1 229 ? -72.784 38.560 31.942 1.00 69.33 ? 262 GLN B OE1 1 ATOM 5118 N NE2 . GLN B 1 229 ? -71.697 40.545 31.879 1.00 63.35 ? 262 GLN B NE2 1 ATOM 5119 N N . ASN B 1 230 ? -68.811 36.494 28.655 1.00 49.08 ? 263 ASN B N 1 ATOM 5120 C CA . ASN B 1 230 ? -69.216 35.137 28.179 1.00 50.91 ? 263 ASN B CA 1 ATOM 5121 C C . ASN B 1 230 ? -69.119 34.925 26.625 1.00 47.03 ? 263 ASN B C 1 ATOM 5122 O O . ASN B 1 230 ? -69.547 33.887 26.096 1.00 49.53 ? 263 ASN B O 1 ATOM 5123 C CB . ASN B 1 230 ? -70.607 34.731 28.765 1.00 46.95 ? 263 ASN B CB 1 ATOM 5124 C CG . ASN B 1 230 ? -70.823 33.215 28.831 1.00 47.25 ? 263 ASN B CG 1 ATOM 5125 O OD1 . ASN B 1 230 ? -71.955 32.729 28.678 1.00 49.22 ? 263 ASN B OD1 1 ATOM 5126 N ND2 . ASN B 1 230 ? -69.750 32.464 29.058 1.00 45.98 ? 263 ASN B ND2 1 ATOM 5127 N N . ILE B 1 231 ? -68.518 35.899 25.939 1.00 41.03 ? 264 ILE B N 1 ATOM 5128 C CA . ILE B 1 231 ? -68.280 35.858 24.514 1.00 40.31 ? 264 ILE B CA 1 ATOM 5129 C C . ILE B 1 231 ? -66.843 35.418 24.307 1.00 38.03 ? 264 ILE B C 1 ATOM 5130 O O . ILE B 1 231 ? -65.911 36.199 24.551 1.00 37.09 ? 264 ILE B O 1 ATOM 5131 C CB . ILE B 1 231 ? -68.409 37.264 23.871 1.00 44.13 ? 264 ILE B CB 1 ATOM 5132 C CG1 . ILE B 1 231 ? -69.862 37.759 23.924 1.00 46.01 ? 264 ILE B CG1 1 ATOM 5133 C CG2 . ILE B 1 231 ? -67.904 37.247 22.429 1.00 41.75 ? 264 ILE B CG2 1 ATOM 5134 C CD1 . ILE B 1 231 ? -70.128 39.036 23.131 1.00 46.50 ? 264 ILE B CD1 1 ATOM 5135 N N . THR B 1 232 ? -66.669 34.157 23.903 1.00 33.45 ? 265 THR B N 1 ATOM 5136 C CA . THR B 1 232 ? -65.447 33.693 23.228 1.00 31.60 ? 265 THR B CA 1 ATOM 5137 C C . THR B 1 232 ? -65.468 33.979 21.702 1.00 31.64 ? 265 THR B C 1 ATOM 5138 O O . THR B 1 232 ? -66.540 33.986 21.067 1.00 36.41 ? 265 THR B O 1 ATOM 5139 C CB . THR B 1 232 ? -65.273 32.195 23.368 1.00 29.54 ? 265 THR B CB 1 ATOM 5140 O OG1 . THR B 1 232 ? -66.415 31.544 22.771 1.00 26.62 ? 265 THR B OG1 1 ATOM 5141 C CG2 . THR B 1 232 ? -65.016 31.802 24.873 1.00 29.74 ? 265 THR B CG2 1 ATOM 5142 N N . ALA B 1 233 ? -64.304 34.197 21.106 1.00 28.85 ? 266 ALA B N 1 ATOM 5143 C CA . ALA B 1 233 ? -64.266 34.400 19.678 1.00 27.54 ? 266 ALA B CA 1 ATOM 5144 C C . ALA B 1 233 ? -64.481 33.094 19.026 1.00 27.34 ? 266 ALA B C 1 ATOM 5145 O O . ALA B 1 233 ? -65.213 33.059 18.055 1.00 31.30 ? 266 ALA B O 1 ATOM 5146 C CB . ALA B 1 233 ? -62.957 34.952 19.224 1.00 31.35 ? 266 ALA B CB 1 ATOM 5147 N N . MET B 1 234 ? -63.897 31.999 19.523 1.00 26.91 ? 267 MET B N 1 ATOM 5148 C CA . MET B 1 234 ? -64.230 30.690 18.903 1.00 26.12 ? 267 MET B CA 1 ATOM 5149 C C . MET B 1 234 ? -65.590 30.245 19.507 1.00 25.81 ? 267 MET B C 1 ATOM 5150 O O . MET B 1 234 ? -66.001 30.811 20.537 1.00 22.72 ? 267 MET B O 1 ATOM 5151 C CB . MET B 1 234 ? -63.125 29.642 19.077 1.00 25.37 ? 267 MET B CB 1 ATOM 5152 C CG . MET B 1 234 ? -61.819 29.946 18.372 1.00 26.69 ? 267 MET B CG 1 ATOM 5153 S SD . MET B 1 234 ? -60.397 29.130 19.147 1.00 26.58 ? 267 MET B SD 1 ATOM 5154 C CE . MET B 1 234 ? -61.298 27.624 19.282 1.00 25.33 ? 267 MET B CE 1 ATOM 5155 N N . ARG B 1 235 ? -66.295 29.304 18.847 1.00 26.08 ? 268 ARG B N 1 ATOM 5156 C CA . ARG B 1 235 ? -67.504 28.623 19.442 1.00 29.30 ? 268 ARG B CA 1 ATOM 5157 C C . ARG B 1 235 ? -67.016 27.747 20.600 1.00 32.91 ? 268 ARG B C 1 ATOM 5158 O O . ARG B 1 235 ? -65.899 27.205 20.505 1.00 38.64 ? 268 ARG B O 1 ATOM 5159 C CB . ARG B 1 235 ? -68.350 27.803 18.410 1.00 26.43 ? 268 ARG B CB 1 ATOM 5160 C CG . ARG B 1 235 ? -68.709 28.539 17.092 1.00 24.39 ? 268 ARG B CG 1 ATOM 5161 C CD . ARG B 1 235 ? -69.742 27.808 16.203 1.00 24.69 ? 268 ARG B CD 1 ATOM 5162 N NE . ARG B 1 235 ? -69.356 27.785 14.784 1.00 24.35 ? 268 ARG B NE 1 ATOM 5163 C CZ . ARG B 1 235 ? -68.922 26.722 14.098 1.00 23.15 ? 268 ARG B CZ 1 ATOM 5164 N NH1 . ARG B 1 235 ? -68.852 25.516 14.610 1.00 25.38 1 268 ARG B NH1 1 ATOM 5165 N NH2 . ARG B 1 235 ? -68.552 26.862 12.865 1.00 23.79 ? 268 ARG B NH2 1 ATOM 5166 N N . GLU B 1 236 ? -67.804 27.640 21.680 1.00 34.51 ? 269 GLU B N 1 ATOM 5167 C CA . GLU B 1 236 ? -67.289 27.149 22.981 1.00 36.39 ? 269 GLU B CA 1 ATOM 5168 C C . GLU B 1 236 ? -66.738 25.694 22.880 1.00 34.95 ? 269 GLU B C 1 ATOM 5169 O O . GLU B 1 236 ? -65.701 25.352 23.534 1.00 29.04 ? 269 GLU B O 1 ATOM 5170 C CB . GLU B 1 236 ? -68.344 27.343 24.107 1.00 40.05 ? 269 GLU B CB 1 ATOM 5171 C CG . GLU B 1 236 ? -67.900 27.128 25.575 1.00 47.22 ? 269 GLU B CG 1 ATOM 5172 C CD . GLU B 1 236 ? -66.695 28.002 26.086 1.00 56.69 ? 269 GLU B CD 1 ATOM 5173 O OE1 . GLU B 1 236 ? -66.524 29.165 25.633 1.00 63.88 ? 269 GLU B OE1 1 ATOM 5174 O OE2 . GLU B 1 236 ? -65.905 27.545 26.977 1.00 49.74 -1 269 GLU B OE2 1 ATOM 5175 N N . TYR B 1 237 ? -67.369 24.878 22.006 1.00 32.57 ? 270 TYR B N 1 ATOM 5176 C CA . TYR B 1 237 ? -67.024 23.439 21.881 1.00 30.75 ? 270 TYR B CA 1 ATOM 5177 C C . TYR B 1 237 ? -65.572 23.314 21.527 1.00 26.63 ? 270 TYR B C 1 ATOM 5178 O O . TYR B 1 237 ? -64.850 22.640 22.215 1.00 26.16 ? 270 TYR B O 1 ATOM 5179 C CB . TYR B 1 237 ? -67.923 22.701 20.884 1.00 34.13 ? 270 TYR B CB 1 ATOM 5180 C CG . TYR B 1 237 ? -67.457 21.278 20.545 1.00 41.62 ? 270 TYR B CG 1 ATOM 5181 C CD1 . TYR B 1 237 ? -67.506 20.241 21.491 1.00 38.58 ? 270 TYR B CD1 1 ATOM 5182 C CD2 . TYR B 1 237 ? -66.992 20.961 19.257 1.00 44.91 ? 270 TYR B CD2 1 ATOM 5183 C CE1 . TYR B 1 237 ? -67.082 18.960 21.177 1.00 38.62 ? 270 TYR B CE1 1 ATOM 5184 C CE2 . TYR B 1 237 ? -66.561 19.677 18.942 1.00 43.85 ? 270 TYR B CE2 1 ATOM 5185 C CZ . TYR B 1 237 ? -66.603 18.683 19.901 1.00 43.08 ? 270 TYR B CZ 1 ATOM 5186 O OH . TYR B 1 237 ? -66.162 17.412 19.550 1.00 44.14 ? 270 TYR B OH 1 ATOM 5187 N N . TYR B 1 238 ? -65.160 24.043 20.498 1.00 26.13 ? 271 TYR B N 1 ATOM 5188 C CA . TYR B 1 238 ? -63.746 24.163 20.005 1.00 26.94 ? 271 TYR B CA 1 ATOM 5189 C C . TYR B 1 238 ? -62.689 24.856 20.954 1.00 23.27 ? 271 TYR B C 1 ATOM 5190 O O . TYR B 1 238 ? -61.547 24.355 21.142 1.00 20.06 ? 271 TYR B O 1 ATOM 5191 C CB . TYR B 1 238 ? -63.730 24.956 18.672 1.00 29.39 ? 271 TYR B CB 1 ATOM 5192 C CG . TYR B 1 238 ? -64.619 24.415 17.566 1.00 30.64 ? 271 TYR B CG 1 ATOM 5193 C CD1 . TYR B 1 238 ? -64.565 23.065 17.164 1.00 34.59 ? 271 TYR B CD1 1 ATOM 5194 C CD2 . TYR B 1 238 ? -65.477 25.258 16.899 1.00 28.62 ? 271 TYR B CD2 1 ATOM 5195 C CE1 . TYR B 1 238 ? -65.385 22.596 16.109 1.00 36.32 ? 271 TYR B CE1 1 ATOM 5196 C CE2 . TYR B 1 238 ? -66.276 24.821 15.870 1.00 30.01 ? 271 TYR B CE2 1 ATOM 5197 C CZ . TYR B 1 238 ? -66.258 23.506 15.461 1.00 33.62 ? 271 TYR B CZ 1 ATOM 5198 O OH . TYR B 1 238 ? -67.101 23.118 14.435 1.00 30.13 ? 271 TYR B OH 1 ATOM 5199 N N . ASN B 1 239 ? -63.050 26.024 21.478 1.00 20.07 ? 272 ASN B N 1 ATOM 5200 C CA . ASN B 1 239 ? -62.216 26.675 22.446 1.00 19.75 ? 272 ASN B CA 1 ATOM 5201 C C . ASN B 1 239 ? -61.799 25.613 23.455 1.00 21.57 ? 272 ASN B C 1 ATOM 5202 O O . ASN B 1 239 ? -60.595 25.393 23.651 1.00 20.70 ? 272 ASN B O 1 ATOM 5203 C CB . ASN B 1 239 ? -62.983 27.814 23.114 1.00 19.45 ? 272 ASN B CB 1 ATOM 5204 C CG . ASN B 1 239 ? -62.159 28.555 24.185 1.00 20.58 ? 272 ASN B CG 1 ATOM 5205 O OD1 . ASN B 1 239 ? -60.979 28.889 23.966 1.00 21.65 ? 272 ASN B OD1 1 ATOM 5206 N ND2 . ASN B 1 239 ? -62.771 28.808 25.360 1.00 20.18 ? 272 ASN B ND2 1 ATOM 5207 N N . GLU B 1 240 ? -62.808 24.936 24.038 1.00 23.03 ? 273 GLU B N 1 ATOM 5208 C CA . GLU B 1 240 ? -62.637 23.852 25.065 1.00 26.01 ? 273 GLU B CA 1 ATOM 5209 C C . GLU B 1 240 ? -61.777 22.595 24.626 1.00 26.42 ? 273 GLU B C 1 ATOM 5210 O O . GLU B 1 240 ? -60.886 22.116 25.336 1.00 24.03 ? 273 GLU B O 1 ATOM 5211 C CB . GLU B 1 240 ? -64.001 23.306 25.466 1.00 25.90 ? 273 GLU B CB 1 ATOM 5212 C CG . GLU B 1 240 ? -64.935 24.275 26.122 1.00 26.95 ? 273 GLU B CG 1 ATOM 5213 C CD . GLU B 1 240 ? -64.666 24.413 27.562 1.00 28.86 ? 273 GLU B CD 1 ATOM 5214 O OE1 . GLU B 1 240 ? -64.688 23.378 28.260 1.00 31.45 ? 273 GLU B OE1 1 ATOM 5215 O OE2 . GLU B 1 240 ? -64.454 25.570 27.994 1.00 33.29 -1 273 GLU B OE2 1 ATOM 5216 N N . LYS B 1 241 ? -62.082 22.046 23.464 1.00 28.26 ? 274 LYS B N 1 ATOM 5217 C CA . LYS B 1 241 ? -61.274 20.966 22.923 1.00 30.53 ? 274 LYS B CA 1 ATOM 5218 C C . LYS B 1 241 ? -59.813 21.431 22.907 1.00 27.11 ? 274 LYS B C 1 ATOM 5219 O O . LYS B 1 241 ? -58.966 20.710 23.427 1.00 26.30 ? 274 LYS B O 1 ATOM 5220 C CB . LYS B 1 241 ? -61.758 20.587 21.502 1.00 33.32 ? 274 LYS B CB 1 ATOM 5221 C CG . LYS B 1 241 ? -60.902 19.536 20.816 1.00 36.50 ? 274 LYS B CG 1 ATOM 5222 C CD . LYS B 1 241 ? -60.837 18.233 21.622 1.00 38.29 ? 274 LYS B CD 1 ATOM 5223 C CE . LYS B 1 241 ? -60.857 16.975 20.762 1.00 36.45 ? 274 LYS B CE 1 ATOM 5224 N NZ . LYS B 1 241 ? -59.806 16.039 21.213 1.00 37.14 1 274 LYS B NZ 1 ATOM 5225 N N . LEU B 1 242 ? -59.556 22.629 22.350 1.00 22.11 ? 275 LEU B N 1 ATOM 5226 C CA . LEU B 1 242 ? -58.205 23.132 22.229 1.00 21.55 ? 275 LEU B CA 1 ATOM 5227 C C . LEU B 1 242 ? -57.537 23.442 23.579 1.00 22.60 ? 275 LEU B C 1 ATOM 5228 O O . LEU B 1 242 ? -56.312 23.213 23.734 1.00 20.49 ? 275 LEU B O 1 ATOM 5229 C CB . LEU B 1 242 ? -58.118 24.395 21.368 1.00 20.69 ? 275 LEU B CB 1 ATOM 5230 C CG . LEU B 1 242 ? -57.798 24.280 19.874 1.00 19.82 ? 275 LEU B CG 1 ATOM 5231 C CD1 . LEU B 1 242 ? -57.928 25.675 19.307 1.00 20.19 ? 275 LEU B CD1 1 ATOM 5232 C CD2 . LEU B 1 242 ? -56.482 23.650 19.427 1.00 18.81 ? 275 LEU B CD2 1 ATOM 5233 N N . ILE B 1 243 ? -58.292 23.977 24.548 1.00 22.02 ? 276 ILE B N 1 ATOM 5234 C CA . ILE B 1 243 ? -57.708 24.173 25.891 1.00 21.61 ? 276 ILE B CA 1 ATOM 5235 C C . ILE B 1 243 ? -57.190 22.859 26.359 1.00 21.52 ? 276 ILE B C 1 ATOM 5236 O O . ILE B 1 243 ? -56.049 22.789 26.750 1.00 20.52 ? 276 ILE B O 1 ATOM 5237 C CB . ILE B 1 243 ? -58.711 24.682 26.937 1.00 21.08 ? 276 ILE B CB 1 ATOM 5238 C CG1 . ILE B 1 243 ? -59.087 26.104 26.633 1.00 22.04 ? 276 ILE B CG1 1 ATOM 5239 C CG2 . ILE B 1 243 ? -58.171 24.537 28.346 1.00 21.17 ? 276 ILE B CG2 1 ATOM 5240 C CD1 . ILE B 1 243 ? -58.013 26.872 25.882 1.00 23.31 ? 276 ILE B CD1 1 ATOM 5241 N N . ASP B 1 244 ? -58.025 21.820 26.259 1.00 22.96 ? 277 ASP B N 1 ATOM 5242 C CA . ASP B 1 244 ? -57.709 20.514 26.841 1.00 25.18 ? 277 ASP B CA 1 ATOM 5243 C C . ASP B 1 244 ? -56.477 19.859 26.212 1.00 21.48 ? 277 ASP B C 1 ATOM 5244 O O . ASP B 1 244 ? -55.693 19.315 26.958 1.00 20.40 ? 277 ASP B O 1 ATOM 5245 C CB . ASP B 1 244 ? -58.985 19.599 26.973 1.00 28.47 ? 277 ASP B CB 1 ATOM 5246 C CG . ASP B 1 244 ? -59.967 20.117 28.140 1.00 38.12 ? 277 ASP B CG 1 ATOM 5247 O OD1 . ASP B 1 244 ? -59.510 20.743 29.208 1.00 34.42 ? 277 ASP B OD1 1 ATOM 5248 O OD2 . ASP B 1 244 ? -61.210 19.927 27.969 1.00 42.57 -1 277 ASP B OD2 1 ATOM 5249 N N . ILE B 1 245 ? -56.304 19.981 24.879 1.00 20.06 ? 278 ILE B N 1 ATOM 5250 C CA . ILE B 1 245 ? -55.050 19.613 24.141 1.00 19.94 ? 278 ILE B CA 1 ATOM 5251 C C . ILE B 1 245 ? -53.792 20.447 24.490 1.00 18.41 ? 278 ILE B C 1 ATOM 5252 O O . ILE B 1 245 ? -52.701 19.936 24.555 1.00 18.29 ? 278 ILE B O 1 ATOM 5253 C CB . ILE B 1 245 ? -55.204 19.687 22.589 1.00 18.83 ? 278 ILE B CB 1 ATOM 5254 C CG1 . ILE B 1 245 ? -56.326 18.752 22.073 1.00 17.06 ? 278 ILE B CG1 1 ATOM 5255 C CG2 . ILE B 1 245 ? -53.860 19.347 21.931 1.00 18.76 ? 278 ILE B CG2 1 ATOM 5256 C CD1 . ILE B 1 245 ? -56.701 19.056 20.647 1.00 16.82 ? 278 ILE B CD1 1 ATOM 5257 N N . PHE B 1 246 ? -53.977 21.724 24.715 1.00 18.33 ? 279 PHE B N 1 ATOM 5258 C CA . PHE B 1 246 ? -52.907 22.578 25.165 1.00 19.25 ? 279 PHE B CA 1 ATOM 5259 C C . PHE B 1 246 ? -52.563 22.232 26.643 1.00 22.94 ? 279 PHE B C 1 ATOM 5260 O O . PHE B 1 246 ? -51.389 22.358 27.031 1.00 24.43 ? 279 PHE B O 1 ATOM 5261 C CB . PHE B 1 246 ? -53.266 24.094 25.013 1.00 17.67 ? 279 PHE B CB 1 ATOM 5262 C CG . PHE B 1 246 ? -53.358 24.630 23.558 1.00 14.95 ? 279 PHE B CG 1 ATOM 5263 C CD1 . PHE B 1 246 ? -52.718 24.014 22.497 1.00 14.39 ? 279 PHE B CD1 1 ATOM 5264 C CD2 . PHE B 1 246 ? -54.053 25.783 23.299 1.00 13.83 ? 279 PHE B CD2 1 ATOM 5265 C CE1 . PHE B 1 246 ? -52.792 24.502 21.225 1.00 13.76 ? 279 PHE B CE1 1 ATOM 5266 C CE2 . PHE B 1 246 ? -54.133 26.289 22.011 1.00 14.07 ? 279 PHE B CE2 1 ATOM 5267 C CZ . PHE B 1 246 ? -53.488 25.655 20.977 1.00 13.95 ? 279 PHE B CZ 1 ATOM 5268 N N . GLN B 1 247 ? -53.545 21.774 27.445 1.00 24.83 ? 280 GLN B N 1 ATOM 5269 C CA . GLN B 1 247 ? -53.287 21.258 28.826 1.00 26.82 ? 280 GLN B CA 1 ATOM 5270 C C . GLN B 1 247 ? -52.483 19.981 28.752 1.00 26.87 ? 280 GLN B C 1 ATOM 5271 O O . GLN B 1 247 ? -51.417 19.920 29.348 1.00 27.96 ? 280 GLN B O 1 ATOM 5272 C CB . GLN B 1 247 ? -54.569 21.092 29.696 1.00 28.73 ? 280 GLN B CB 1 ATOM 5273 C CG . GLN B 1 247 ? -55.062 22.458 30.264 1.00 30.16 ? 280 GLN B CG 1 ATOM 5274 C CD . GLN B 1 247 ? -56.536 22.545 30.616 1.00 29.09 ? 280 GLN B CD 1 ATOM 5275 O OE1 . GLN B 1 247 ? -57.362 21.824 30.058 1.00 38.65 ? 280 GLN B OE1 1 ATOM 5276 N NE2 . GLN B 1 247 ? -56.873 23.400 31.550 1.00 25.92 ? 280 GLN B NE2 1 ATOM 5277 N N . LYS B 1 248 ? -52.931 19.007 27.955 1.00 27.79 ? 281 LYS B N 1 ATOM 5278 C CA . LYS B 1 248 ? -52.156 17.772 27.706 1.00 29.61 ? 281 LYS B CA 1 ATOM 5279 C C . LYS B 1 248 ? -50.677 18.024 27.332 1.00 28.23 ? 281 LYS B C 1 ATOM 5280 O O . LYS B 1 248 ? -49.824 17.213 27.624 1.00 30.53 ? 281 LYS B O 1 ATOM 5281 C CB . LYS B 1 248 ? -52.799 16.896 26.607 1.00 34.04 ? 281 LYS B CB 1 ATOM 5282 C CG . LYS B 1 248 ? -54.060 16.148 27.022 1.00 39.10 ? 281 LYS B CG 1 ATOM 5283 C CD . LYS B 1 248 ? -54.485 15.122 25.962 1.00 47.55 ? 281 LYS B CD 1 ATOM 5284 C CE . LYS B 1 248 ? -56.022 14.994 25.784 1.00 49.59 ? 281 LYS B CE 1 ATOM 5285 N NZ . LYS B 1 248 ? -56.763 14.753 27.066 1.00 47.93 1 281 LYS B NZ 1 ATOM 5286 N N . TYR B 1 249 ? -50.355 19.122 26.675 1.00 25.27 ? 282 TYR B N 1 ATOM 5287 C CA . TYR B 1 249 ? -49.052 19.225 26.089 1.00 23.29 ? 282 TYR B CA 1 ATOM 5288 C C . TYR B 1 249 ? -48.388 20.514 26.455 1.00 23.25 ? 282 TYR B C 1 ATOM 5289 O O . TYR B 1 249 ? -47.516 20.979 25.721 1.00 23.67 ? 282 TYR B O 1 ATOM 5290 C CB . TYR B 1 249 ? -49.179 19.115 24.556 1.00 23.03 ? 282 TYR B CB 1 ATOM 5291 C CG . TYR B 1 249 ? -49.518 17.765 24.100 1.00 21.67 ? 282 TYR B CG 1 ATOM 5292 C CD1 . TYR B 1 249 ? -48.503 16.809 23.851 1.00 21.52 ? 282 TYR B CD1 1 ATOM 5293 C CD2 . TYR B 1 249 ? -50.848 17.399 23.960 1.00 21.88 ? 282 TYR B CD2 1 ATOM 5294 C CE1 . TYR B 1 249 ? -48.826 15.509 23.479 1.00 20.76 ? 282 TYR B CE1 1 ATOM 5295 C CE2 . TYR B 1 249 ? -51.181 16.104 23.594 1.00 23.50 ? 282 TYR B CE2 1 ATOM 5296 C CZ . TYR B 1 249 ? -50.172 15.168 23.369 1.00 22.35 ? 282 TYR B CZ 1 ATOM 5297 O OH . TYR B 1 249 ? -50.570 13.930 22.941 1.00 22.91 ? 282 TYR B OH 1 ATOM 5298 N N . SER B 1 250 ? -48.771 21.100 27.576 1.00 24.29 ? 283 SER B N 1 ATOM 5299 C CA . SER B 1 250 ? -48.122 22.349 28.048 1.00 26.68 ? 283 SER B CA 1 ATOM 5300 C C . SER B 1 250 ? -46.613 22.234 28.310 1.00 29.58 ? 283 SER B C 1 ATOM 5301 O O . SER B 1 250 ? -45.920 23.262 28.325 1.00 33.94 ? 283 SER B O 1 ATOM 5302 C CB . SER B 1 250 ? -48.814 22.939 29.294 1.00 25.37 ? 283 SER B CB 1 ATOM 5303 O OG . SER B 1 250 ? -48.525 22.165 30.415 1.00 24.57 ? 283 SER B OG 1 ATOM 5304 N N . ASP B 1 251 ? -46.113 21.005 28.508 1.00 31.27 ? 284 ASP B N 1 ATOM 5305 C CA . ASP B 1 251 ? -44.656 20.741 28.553 1.00 33.57 ? 284 ASP B CA 1 ATOM 5306 C C . ASP B 1 251 ? -43.990 21.246 27.217 1.00 31.09 ? 284 ASP B C 1 ATOM 5307 O O . ASP B 1 251 ? -43.187 22.198 27.198 1.00 25.51 ? 284 ASP B O 1 ATOM 5308 C CB . ASP B 1 251 ? -44.326 19.258 28.982 1.00 36.04 ? 284 ASP B CB 1 ATOM 5309 C CG . ASP B 1 251 ? -44.798 18.107 27.918 1.00 45.59 ? 284 ASP B CG 1 ATOM 5310 O OD1 . ASP B 1 251 ? -46.024 17.943 27.545 1.00 40.35 ? 284 ASP B OD1 1 ATOM 5311 O OD2 . ASP B 1 251 ? -43.898 17.296 27.490 1.00 52.97 -1 284 ASP B OD2 1 ATOM 5312 N N . VAL B 1 252 ? -44.460 20.695 26.102 1.00 31.53 ? 285 VAL B N 1 ATOM 5313 C CA . VAL B 1 252 ? -43.818 20.876 24.789 1.00 32.24 ? 285 VAL B CA 1 ATOM 5314 C C . VAL B 1 252 ? -44.023 22.271 24.199 1.00 28.89 ? 285 VAL B C 1 ATOM 5315 O O . VAL B 1 252 ? -43.168 22.778 23.475 1.00 27.47 ? 285 VAL B O 1 ATOM 5316 C CB . VAL B 1 252 ? -44.312 19.786 23.801 1.00 34.12 ? 285 VAL B CB 1 ATOM 5317 C CG1 . VAL B 1 252 ? -43.617 19.886 22.446 1.00 36.29 ? 285 VAL B CG1 1 ATOM 5318 C CG2 . VAL B 1 252 ? -44.028 18.420 24.390 1.00 38.79 ? 285 VAL B CG2 1 ATOM 5319 N N . ILE B 1 253 ? -45.182 22.848 24.503 1.00 28.74 ? 286 ILE B N 1 ATOM 5320 C CA . ILE B 1 253 ? -45.526 24.160 24.066 1.00 27.14 ? 286 ILE B CA 1 ATOM 5321 C C . ILE B 1 253 ? -44.853 25.112 25.067 1.00 26.59 ? 286 ILE B C 1 ATOM 5322 O O . ILE B 1 253 ? -44.891 24.921 26.296 1.00 28.43 ? 286 ILE B O 1 ATOM 5323 C CB . ILE B 1 253 ? -47.050 24.338 23.944 1.00 27.73 ? 286 ILE B CB 1 ATOM 5324 C CG1 . ILE B 1 253 ? -47.613 23.310 22.945 1.00 25.93 ? 286 ILE B CG1 1 ATOM 5325 C CG2 . ILE B 1 253 ? -47.385 25.758 23.467 1.00 30.07 ? 286 ILE B CG2 1 ATOM 5326 C CD1 . ILE B 1 253 ? -49.114 23.211 22.937 1.00 25.03 ? 286 ILE B CD1 1 ATOM 5327 N N . ALA B 1 254 ? -44.155 26.068 24.484 1.00 21.76 ? 287 ALA B N 1 ATOM 5328 C CA . ALA B 1 254 ? -43.364 27.028 25.169 1.00 19.94 ? 287 ALA B CA 1 ATOM 5329 C C . ALA B 1 254 ? -43.867 28.429 24.912 1.00 18.94 ? 287 ALA B C 1 ATOM 5330 O O . ALA B 1 254 ? -43.246 29.387 25.398 1.00 16.31 ? 287 ALA B O 1 ATOM 5331 C CB . ALA B 1 254 ? -41.928 26.932 24.635 1.00 19.45 ? 287 ALA B CB 1 ATOM 5332 N N . GLY B 1 255 ? -44.911 28.532 24.077 1.00 18.44 ? 288 GLY B N 1 ATOM 5333 C CA . GLY B 1 255 ? -45.466 29.830 23.642 1.00 19.25 ? 288 GLY B CA 1 ATOM 5334 C C . GLY B 1 255 ? -46.632 29.749 22.635 1.00 19.39 ? 288 GLY B C 1 ATOM 5335 O O . GLY B 1 255 ? -46.633 28.846 21.771 1.00 18.97 ? 288 GLY B O 1 ATOM 5336 N N . GLN B 1 256 ? -47.633 30.643 22.787 1.00 17.34 ? 289 GLN B N 1 ATOM 5337 C CA . GLN B 1 256 ? -48.705 30.803 21.802 1.00 16.60 ? 289 GLN B CA 1 ATOM 5338 C C . GLN B 1 256 ? -48.856 32.237 21.423 1.00 15.60 ? 289 GLN B C 1 ATOM 5339 O O . GLN B 1 256 ? -48.746 33.153 22.249 1.00 13.16 ? 289 GLN B O 1 ATOM 5340 C CB . GLN B 1 256 ? -50.065 30.340 22.295 1.00 16.84 ? 289 GLN B CB 1 ATOM 5341 C CG . GLN B 1 256 ? -50.120 28.852 22.432 1.00 18.38 ? 289 GLN B CG 1 ATOM 5342 C CD . GLN B 1 256 ? -51.297 28.403 23.247 1.00 20.12 ? 289 GLN B CD 1 ATOM 5343 O OE1 . GLN B 1 256 ? -52.418 28.782 22.911 1.00 23.03 ? 289 GLN B OE1 1 ATOM 5344 N NE2 . GLN B 1 256 ? -51.065 27.646 24.359 1.00 18.67 ? 289 GLN B NE2 1 ATOM 5345 N N . PHE B 1 257 ? -49.145 32.431 20.141 1.00 15.15 ? 290 PHE B N 1 ATOM 5346 C CA . PHE B 1 257 ? -49.172 33.766 19.605 1.00 14.59 ? 290 PHE B CA 1 ATOM 5347 C C . PHE B 1 257 ? -50.373 33.915 18.621 1.00 14.93 ? 290 PHE B C 1 ATOM 5348 O O . PHE B 1 257 ? -50.603 33.037 17.691 1.00 15.94 ? 290 PHE B O 1 ATOM 5349 C CB . PHE B 1 257 ? -47.802 34.126 18.956 1.00 14.08 ? 290 PHE B CB 1 ATOM 5350 C CG . PHE B 1 257 ? -46.584 33.775 19.777 1.00 13.70 ? 290 PHE B CG 1 ATOM 5351 C CD1 . PHE B 1 257 ? -46.037 34.696 20.667 1.00 14.04 ? 290 PHE B CD1 1 ATOM 5352 C CD2 . PHE B 1 257 ? -45.955 32.525 19.644 1.00 13.50 ? 290 PHE B CD2 1 ATOM 5353 C CE1 . PHE B 1 257 ? -44.891 34.400 21.398 1.00 13.68 ? 290 PHE B CE1 1 ATOM 5354 C CE2 . PHE B 1 257 ? -44.828 32.226 20.388 1.00 13.02 ? 290 PHE B CE2 1 ATOM 5355 C CZ . PHE B 1 257 ? -44.285 33.165 21.248 1.00 13.13 ? 290 PHE B CZ 1 ATOM 5356 N N . TYR B 1 258 ? -51.133 35.009 18.827 1.00 13.43 ? 291 TYR B N 1 ATOM 5357 C CA . TYR B 1 258 ? -52.430 35.207 18.151 1.00 12.58 ? 291 TYR B CA 1 ATOM 5358 C C . TYR B 1 258 ? -52.505 36.601 17.635 1.00 12.19 ? 291 TYR B C 1 ATOM 5359 O O . TYR B 1 258 ? -51.669 37.366 17.951 1.00 13.67 ? 291 TYR B O 1 ATOM 5360 C CB . TYR B 1 258 ? -53.567 34.909 19.132 1.00 13.20 ? 291 TYR B CB 1 ATOM 5361 C CG . TYR B 1 258 ? -53.606 33.446 19.705 1.00 12.47 ? 291 TYR B CG 1 ATOM 5362 C CD1 . TYR B 1 258 ? -54.008 32.395 18.875 1.00 12.84 ? 291 TYR B CD1 1 ATOM 5363 C CD2 . TYR B 1 258 ? -53.190 33.143 21.014 1.00 11.62 ? 291 TYR B CD2 1 ATOM 5364 C CE1 . TYR B 1 258 ? -54.050 31.095 19.326 1.00 13.24 ? 291 TYR B CE1 1 ATOM 5365 C CE2 . TYR B 1 258 ? -53.187 31.847 21.490 1.00 11.79 ? 291 TYR B CE2 1 ATOM 5366 C CZ . TYR B 1 258 ? -53.627 30.828 20.651 1.00 13.13 ? 291 TYR B CZ 1 ATOM 5367 O OH . TYR B 1 258 ? -53.712 29.515 21.032 1.00 13.66 ? 291 TYR B OH 1 ATOM 5368 N N . GLY B 1 259 ? -53.432 36.910 16.754 1.00 12.56 ? 292 GLY B N 1 ATOM 5369 C CA . GLY B 1 259 ? -53.720 38.288 16.253 1.00 11.82 ? 292 GLY B CA 1 ATOM 5370 C C . GLY B 1 259 ? -55.241 38.504 16.388 1.00 12.32 ? 292 GLY B C 1 ATOM 5371 O O . GLY B 1 259 ? -55.801 38.155 17.456 1.00 11.91 ? 292 GLY B O 1 ATOM 5372 N N . HIS B 1 260 ? -55.910 39.093 15.370 1.00 11.57 ? 293 HIS B N 1 ATOM 5373 C CA . HIS B 1 260 ? -57.374 39.019 15.159 1.00 10.78 ? 293 HIS B CA 1 ATOM 5374 C C . HIS B 1 260 ? -58.137 39.998 15.907 1.00 10.02 ? 293 HIS B C 1 ATOM 5375 O O . HIS B 1 260 ? -59.001 40.733 15.362 1.00 10.80 ? 293 HIS B O 1 ATOM 5376 C CB . HIS B 1 260 ? -57.974 37.674 15.453 1.00 12.18 ? 293 HIS B CB 1 ATOM 5377 C CG . HIS B 1 260 ? -59.471 37.629 15.331 1.00 15.08 ? 293 HIS B CG 1 ATOM 5378 N ND1 . HIS B 1 260 ? -60.131 37.715 14.119 1.00 14.46 ? 293 HIS B ND1 1 ATOM 5379 C CD2 . HIS B 1 260 ? -60.444 37.447 16.285 1.00 16.89 ? 293 HIS B CD2 1 ATOM 5380 C CE1 . HIS B 1 260 ? -61.435 37.661 14.331 1.00 15.96 ? 293 HIS B CE1 1 ATOM 5381 N NE2 . HIS B 1 260 ? -61.651 37.495 15.633 1.00 17.96 ? 293 HIS B NE2 1 ATOM 5382 N N A THR B 1 261 ? -57.890 40.113 17.208 0.50 9.56 ? 294 THR B N 1 ATOM 5383 N N B THR B 1 261 ? -57.796 40.082 17.160 0.50 9.73 ? 294 THR B N 1 ATOM 5384 C CA A THR B 1 261 ? -58.634 41.077 18.022 0.50 8.66 ? 294 THR B CA 1 ATOM 5385 C CA B THR B 1 261 ? -58.551 40.835 18.044 0.50 8.89 ? 294 THR B CA 1 ATOM 5386 C C A THR B 1 261 ? -58.163 42.415 17.874 0.50 8.61 ? 294 THR B C 1 ATOM 5387 C C B THR B 1 261 ? -57.818 42.064 18.272 0.50 8.81 ? 294 THR B C 1 ATOM 5388 O O A THR B 1 261 ? -58.835 43.350 18.143 0.50 8.54 ? 294 THR B O 1 ATOM 5389 O O B THR B 1 261 ? -57.838 42.467 19.330 0.50 9.58 ? 294 THR B O 1 ATOM 5390 C CB A THR B 1 261 ? -58.418 40.801 19.430 0.50 8.56 ? 294 THR B CB 1 ATOM 5391 C CB B THR B 1 261 ? -58.714 39.946 19.283 0.50 8.82 ? 294 THR B CB 1 ATOM 5392 O OG1 A THR B 1 261 ? -57.043 41.073 19.669 0.50 8.00 ? 294 THR B OG1 1 ATOM 5393 O OG1 B THR B 1 261 ? -59.380 38.706 18.913 0.50 7.22 ? 294 THR B OG1 1 ATOM 5394 C CG2 A THR B 1 261 ? -58.885 39.271 19.702 0.50 8.63 ? 294 THR B CG2 1 ATOM 5395 C CG2 B THR B 1 261 ? -59.416 40.684 20.412 0.50 8.96 ? 294 THR B CG2 1 ATOM 5396 N N . HIS B 1 262 ? -57.013 42.531 17.318 1.00 9.91 ? 295 HIS B N 1 ATOM 5397 C CA . HIS B 1 262 ? -56.262 43.880 17.216 1.00 11.58 ? 295 HIS B CA 1 ATOM 5398 C C . HIS B 1 262 ? -55.713 44.695 18.424 1.00 13.90 ? 295 HIS B C 1 ATOM 5399 O O . HIS B 1 262 ? -55.445 45.951 18.314 1.00 15.93 ? 295 HIS B O 1 ATOM 5400 C CB . HIS B 1 262 ? -57.046 44.867 16.399 1.00 12.14 ? 295 HIS B CB 1 ATOM 5401 C CG . HIS B 1 262 ? -57.312 44.429 15.026 1.00 12.40 ? 295 HIS B CG 1 ATOM 5402 N ND1 . HIS B 1 262 ? -57.523 45.332 14.022 1.00 13.16 ? 295 HIS B ND1 1 ATOM 5403 C CD2 . HIS B 1 262 ? -57.474 43.205 14.484 1.00 12.55 ? 295 HIS B CD2 1 ATOM 5404 C CE1 . HIS B 1 262 ? -57.792 44.681 12.897 1.00 13.13 ? 295 HIS B CE1 1 ATOM 5405 N NE2 . HIS B 1 262 ? -57.762 43.391 13.155 1.00 13.06 ? 295 HIS B NE2 1 ATOM 5406 N N . ARG B 1 263 ? -55.516 43.993 19.538 1.00 14.88 ? 296 ARG B N 1 ATOM 5407 C CA . ARG B 1 263 ? -55.303 44.574 20.836 1.00 15.30 ? 296 ARG B CA 1 ATOM 5408 C C . ARG B 1 263 ? -54.086 43.883 21.392 1.00 15.88 ? 296 ARG B C 1 ATOM 5409 O O . ARG B 1 263 ? -53.878 42.658 21.072 1.00 16.90 ? 296 ARG B O 1 ATOM 5410 C CB . ARG B 1 263 ? -56.585 44.268 21.689 1.00 14.69 ? 296 ARG B CB 1 ATOM 5411 C CG . ARG B 1 263 ? -57.775 44.990 21.106 1.00 14.08 ? 296 ARG B CG 1 ATOM 5412 C CD . ARG B 1 263 ? -57.529 46.450 21.378 1.00 15.00 ? 296 ARG B CD 1 ATOM 5413 N NE . ARG B 1 263 ? -58.621 47.253 20.919 1.00 17.54 ? 296 ARG B NE 1 ATOM 5414 C CZ . ARG B 1 263 ? -58.765 47.793 19.702 1.00 19.82 ? 296 ARG B CZ 1 ATOM 5415 N NH1 . ARG B 1 263 ? -57.830 47.688 18.735 1.00 20.51 1 296 ARG B NH1 1 ATOM 5416 N NH2 . ARG B 1 263 ? -59.891 48.451 19.443 1.00 20.70 ? 296 ARG B NH2 1 ATOM 5417 N N . ASP B 1 264 ? -53.322 44.613 22.225 1.00 15.03 ? 297 ASP B N 1 ATOM 5418 C CA . ASP B 1 264 ? -52.287 43.989 23.028 1.00 15.45 ? 297 ASP B CA 1 ATOM 5419 C C . ASP B 1 264 ? -52.741 43.282 24.367 1.00 16.38 ? 297 ASP B C 1 ATOM 5420 O O . ASP B 1 264 ? -53.075 43.913 25.347 1.00 16.59 ? 297 ASP B O 1 ATOM 5421 C CB . ASP B 1 264 ? -51.218 44.961 23.279 1.00 15.83 ? 297 ASP B CB 1 ATOM 5422 C CG . ASP B 1 264 ? -50.089 44.374 24.066 1.00 16.76 ? 297 ASP B CG 1 ATOM 5423 O OD1 . ASP B 1 264 ? -50.285 43.289 24.700 1.00 19.14 ? 297 ASP B OD1 1 ATOM 5424 O OD2 . ASP B 1 264 ? -49.001 45.018 24.076 1.00 16.69 -1 297 ASP B OD2 1 ATOM 5425 N N . SER B 1 265 ? -52.657 41.962 24.392 1.00 16.98 ? 298 SER B N 1 ATOM 5426 C CA . SER B 1 265 ? -53.207 41.211 25.451 1.00 20.15 ? 298 SER B CA 1 ATOM 5427 C C . SER B 1 265 ? -52.371 39.991 25.836 1.00 20.70 ? 298 SER B C 1 ATOM 5428 O O . SER B 1 265 ? -51.460 39.535 25.097 1.00 21.93 ? 298 SER B O 1 ATOM 5429 C CB . SER B 1 265 ? -54.628 40.741 25.076 1.00 23.80 ? 298 SER B CB 1 ATOM 5430 O OG . SER B 1 265 ? -55.679 41.354 25.859 1.00 28.25 ? 298 SER B OG 1 ATOM 5431 N N A ILE B 1 266 ? -52.728 39.426 26.983 0.50 18.64 ? 299 ILE B N 1 ATOM 5432 N N B ILE B 1 266 ? -52.668 39.477 27.021 0.50 19.36 ? 299 ILE B N 1 ATOM 5433 C CA A ILE B 1 266 ? -52.070 38.253 27.463 0.50 17.38 ? 299 ILE B CA 1 ATOM 5434 C CA B ILE B 1 266 ? -52.084 38.250 27.449 0.50 18.50 ? 299 ILE B CA 1 ATOM 5435 C C A ILE B 1 266 ? -53.100 37.380 28.111 0.50 17.74 ? 299 ILE B C 1 ATOM 5436 C C B ILE B 1 266 ? -53.149 37.380 28.038 0.50 18.35 ? 299 ILE B C 1 ATOM 5437 O O A ILE B 1 266 ? -54.071 37.873 28.664 0.50 16.66 ? 299 ILE B O 1 ATOM 5438 O O B ILE B 1 266 ? -54.170 37.874 28.501 0.50 17.08 ? 299 ILE B O 1 ATOM 5439 C CB A ILE B 1 266 ? -50.957 38.650 28.399 0.50 16.26 ? 299 ILE B CB 1 ATOM 5440 C CB B ILE B 1 266 ? -51.018 38.474 28.479 0.50 18.18 ? 299 ILE B CB 1 ATOM 5441 C CG1 A ILE B 1 266 ? -51.363 38.421 29.862 0.50 15.72 ? 299 ILE B CG1 1 ATOM 5442 C CG1 B ILE B 1 266 ? -50.301 37.181 28.768 0.50 18.08 ? 299 ILE B CG1 1 ATOM 5443 C CG2 A ILE B 1 266 ? -50.595 40.087 28.060 0.50 16.22 ? 299 ILE B CG2 1 ATOM 5444 C CG2 B ILE B 1 266 ? -51.626 38.937 29.773 0.50 18.71 ? 299 ILE B CG2 1 ATOM 5445 C CD1 A ILE B 1 266 ? -50.587 39.218 30.920 0.50 14.97 ? 299 ILE B CD1 1 ATOM 5446 C CD1 B ILE B 1 266 ? -50.201 36.970 30.248 0.50 18.76 ? 299 ILE B CD1 1 ATOM 5447 N N . MET B 1 267 ? -52.918 36.074 27.941 1.00 19.28 ? 300 MET B N 1 ATOM 5448 C CA . MET B 1 267 ? -53.747 35.034 28.605 1.00 19.49 ? 300 MET B CA 1 ATOM 5449 C C . MET B 1 267 ? -52.793 34.039 29.252 1.00 17.66 ? 300 MET B C 1 ATOM 5450 O O . MET B 1 267 ? -51.734 33.794 28.718 1.00 16.28 ? 300 MET B O 1 ATOM 5451 C CB . MET B 1 267 ? -54.701 34.317 27.599 1.00 19.76 ? 300 MET B CB 1 ATOM 5452 C CG . MET B 1 267 ? -56.045 35.024 27.405 1.00 18.97 ? 300 MET B CG 1 ATOM 5453 S SD . MET B 1 267 ? -57.158 34.256 26.217 1.00 20.35 ? 300 MET B SD 1 ATOM 5454 C CE . MET B 1 267 ? -56.255 34.584 24.739 1.00 20.30 ? 300 MET B CE 1 ATOM 5455 N N . VAL B 1 268 ? -53.165 33.506 30.429 1.00 18.59 ? 301 VAL B N 1 ATOM 5456 C CA . VAL B 1 268 ? -52.384 32.440 31.088 1.00 17.06 ? 301 VAL B CA 1 ATOM 5457 C C . VAL B 1 268 ? -53.168 31.153 31.222 1.00 16.25 ? 301 VAL B C 1 ATOM 5458 O O . VAL B 1 268 ? -54.153 31.124 31.918 1.00 15.46 ? 301 VAL B O 1 ATOM 5459 C CB . VAL B 1 268 ? -51.890 32.876 32.432 1.00 17.16 ? 301 VAL B CB 1 ATOM 5460 C CG1 . VAL B 1 268 ? -51.465 31.622 33.180 1.00 17.54 ? 301 VAL B CG1 1 ATOM 5461 C CG2 . VAL B 1 268 ? -50.778 33.965 32.287 1.00 17.04 ? 301 VAL B CG2 1 ATOM 5462 N N . LEU B 1 269 ? -52.751 30.123 30.479 1.00 17.24 ? 302 LEU B N 1 ATOM 5463 C CA . LEU B 1 269 ? -53.352 28.791 30.535 1.00 18.52 ? 302 LEU B CA 1 ATOM 5464 C C . LEU B 1 269 ? -52.805 28.018 31.723 1.00 19.85 ? 302 LEU B C 1 ATOM 5465 O O . LEU B 1 269 ? -51.580 27.776 31.781 1.00 19.47 ? 302 LEU B O 1 ATOM 5466 C CB . LEU B 1 269 ? -53.100 27.967 29.235 1.00 19.94 ? 302 LEU B CB 1 ATOM 5467 C CG . LEU B 1 269 ? -53.682 26.484 29.224 1.00 20.04 ? 302 LEU B CG 1 ATOM 5468 C CD1 . LEU B 1 269 ? -55.201 26.502 29.277 1.00 18.86 ? 302 LEU B CD1 1 ATOM 5469 C CD2 . LEU B 1 269 ? -53.198 25.599 28.063 1.00 19.50 ? 302 LEU B CD2 1 ATOM 5470 N N . SER B 1 270 ? -53.723 27.645 32.637 1.00 21.91 ? 303 SER B N 1 ATOM 5471 C CA . SER B 1 270 ? -53.489 26.735 33.779 1.00 25.15 ? 303 SER B CA 1 ATOM 5472 C C . SER B 1 270 ? -53.845 25.309 33.460 1.00 29.50 ? 303 SER B C 1 ATOM 5473 O O . SER B 1 270 ? -54.710 25.038 32.619 1.00 29.30 ? 303 SER B O 1 ATOM 5474 C CB . SER B 1 270 ? -54.301 27.121 35.008 1.00 24.22 ? 303 SER B CB 1 ATOM 5475 O OG . SER B 1 270 ? -53.667 28.191 35.647 1.00 26.37 ? 303 SER B OG 1 ATOM 5476 N N . ASP B 1 271 ? -53.177 24.383 34.144 1.00 36.04 ? 304 ASP B N 1 ATOM 5477 C CA . ASP B 1 271 ? -53.439 22.947 33.947 1.00 40.59 ? 304 ASP B CA 1 ATOM 5478 C C . ASP B 1 271 ? -54.635 22.670 34.846 1.00 44.58 ? 304 ASP B C 1 ATOM 5479 O O . ASP B 1 271 ? -55.088 23.554 35.564 1.00 48.33 ? 304 ASP B O 1 ATOM 5480 C CB . ASP B 1 271 ? -52.209 22.091 34.256 1.00 37.50 ? 304 ASP B CB 1 ATOM 5481 C CG . ASP B 1 271 ? -52.011 21.832 35.750 1.00 39.65 ? 304 ASP B CG 1 ATOM 5482 O OD1 . ASP B 1 271 ? -52.617 22.511 36.626 1.00 36.16 ? 304 ASP B OD1 1 ATOM 5483 O OD2 . ASP B 1 271 ? -51.203 20.930 36.047 1.00 42.48 -1 304 ASP B OD2 1 ATOM 5484 N N . LYS B 1 272 ? -55.155 21.461 34.843 1.00 53.16 ? 305 LYS B N 1 ATOM 5485 C CA . LYS B 1 272 ? -56.513 21.284 35.361 1.00 53.91 ? 305 LYS B CA 1 ATOM 5486 C C . LYS B 1 272 ? -56.687 21.481 36.887 1.00 47.11 ? 305 LYS B C 1 ATOM 5487 O O . LYS B 1 272 ? -57.778 21.375 37.368 1.00 45.31 ? 305 LYS B O 1 ATOM 5488 C CB . LYS B 1 272 ? -57.070 19.960 34.865 1.00 56.01 ? 305 LYS B CB 1 ATOM 5489 C CG . LYS B 1 272 ? -57.004 19.845 33.348 1.00 56.01 ? 305 LYS B CG 1 ATOM 5490 C CD . LYS B 1 272 ? -57.812 18.649 32.885 1.00 60.59 ? 305 LYS B CD 1 ATOM 5491 C CE . LYS B 1 272 ? -58.338 18.839 31.480 1.00 66.98 ? 305 LYS B CE 1 ATOM 5492 N NZ . LYS B 1 272 ? -57.248 19.204 30.529 1.00 71.18 1 305 LYS B NZ 1 ATOM 5493 N N . LYS B 1 273 ? -55.631 21.849 37.609 1.00 48.71 ? 306 LYS B N 1 ATOM 5494 C CA . LYS B 1 273 ? -55.693 22.089 39.061 1.00 51.70 ? 306 LYS B CA 1 ATOM 5495 C C . LYS B 1 273 ? -55.090 23.454 39.449 1.00 50.48 ? 306 LYS B C 1 ATOM 5496 O O . LYS B 1 273 ? -54.477 23.593 40.541 1.00 50.52 ? 306 LYS B O 1 ATOM 5497 C CB . LYS B 1 273 ? -54.968 20.952 39.831 1.00 53.35 ? 306 LYS B CB 1 ATOM 5498 C CG . LYS B 1 273 ? -55.285 20.824 41.333 1.00 58.12 ? 306 LYS B CG 1 ATOM 5499 C CD . LYS B 1 273 ? -56.750 20.479 41.665 1.00 60.20 ? 306 LYS B CD 1 ATOM 5500 C CE . LYS B 1 273 ? -57.438 21.544 42.531 1.00 59.73 ? 306 LYS B CE 1 ATOM 5501 N NZ . LYS B 1 273 ? -56.789 21.718 43.874 1.00 53.67 1 306 LYS B NZ 1 ATOM 5502 N N . GLY B 1 274 ? -55.245 24.450 38.572 1.00 37.04 ? 307 GLY B N 1 ATOM 5503 C CA . GLY B 1 274 ? -54.999 25.831 38.980 1.00 34.94 ? 307 GLY B CA 1 ATOM 5504 C C . GLY B 1 274 ? -53.604 26.364 38.725 1.00 34.96 ? 307 GLY B C 1 ATOM 5505 O O . GLY B 1 274 ? -53.322 27.561 38.923 1.00 31.11 ? 307 GLY B O 1 ATOM 5506 N N . SER B 1 275 ? -52.736 25.478 38.236 1.00 32.88 ? 308 SER B N 1 ATOM 5507 C CA . SER B 1 275 ? -51.328 25.796 38.033 1.00 30.01 ? 308 SER B CA 1 ATOM 5508 C C . SER B 1 275 ? -51.071 26.416 36.627 1.00 28.41 ? 308 SER B C 1 ATOM 5509 O O . SER B 1 275 ? -51.524 25.863 35.631 1.00 26.76 ? 308 SER B O 1 ATOM 5510 C CB . SER B 1 275 ? -50.516 24.511 38.211 1.00 28.60 ? 308 SER B CB 1 ATOM 5511 O OG . SER B 1 275 ? -49.396 24.726 39.054 1.00 31.05 ? 308 SER B OG 1 ATOM 5512 N N . PRO B 1 276 ? -50.303 27.528 36.532 1.00 24.79 ? 309 PRO B N 1 ATOM 5513 C CA . PRO B 1 276 ? -50.062 28.099 35.228 1.00 22.94 ? 309 PRO B CA 1 ATOM 5514 C C . PRO B 1 276 ? -49.095 27.249 34.436 1.00 20.76 ? 309 PRO B C 1 ATOM 5515 O O . PRO B 1 276 ? -48.119 26.835 34.962 1.00 22.51 ? 309 PRO B O 1 ATOM 5516 C CB . PRO B 1 276 ? -49.433 29.465 35.544 1.00 22.36 ? 309 PRO B CB 1 ATOM 5517 C CG . PRO B 1 276 ? -49.182 29.455 36.977 1.00 24.45 ? 309 PRO B CG 1 ATOM 5518 C CD . PRO B 1 276 ? -49.325 28.044 37.476 1.00 24.50 ? 309 PRO B CD 1 ATOM 5519 N N . VAL B 1 277 ? -49.350 27.004 33.174 1.00 19.43 ? 310 VAL B N 1 ATOM 5520 C CA . VAL B 1 277 ? -48.464 26.139 32.412 1.00 20.71 ? 310 VAL B CA 1 ATOM 5521 C C . VAL B 1 277 ? -48.160 26.578 30.978 1.00 19.44 ? 310 VAL B C 1 ATOM 5522 O O . VAL B 1 277 ? -47.296 25.963 30.330 1.00 17.07 ? 310 VAL B O 1 ATOM 5523 C CB . VAL B 1 277 ? -49.040 24.681 32.308 1.00 23.12 ? 310 VAL B CB 1 ATOM 5524 C CG1 . VAL B 1 277 ? -49.096 24.017 33.698 1.00 23.69 ? 310 VAL B CG1 1 ATOM 5525 C CG2 . VAL B 1 277 ? -50.412 24.641 31.598 1.00 22.14 ? 310 VAL B CG2 1 ATOM 5526 N N . ASN B 1 278 ? -48.892 27.594 30.492 1.00 19.28 ? 311 ASN B N 1 ATOM 5527 C CA . ASN B 1 278 ? -48.688 28.189 29.145 1.00 18.20 ? 311 ASN B CA 1 ATOM 5528 C C . ASN B 1 278 ? -49.022 29.672 29.142 1.00 16.09 ? 311 ASN B C 1 ATOM 5529 O O . ASN B 1 278 ? -50.060 30.043 29.638 1.00 14.22 ? 311 ASN B O 1 ATOM 5530 C CB . ASN B 1 278 ? -49.608 27.501 28.119 1.00 19.12 ? 311 ASN B CB 1 ATOM 5531 C CG . ASN B 1 278 ? -48.850 26.887 26.928 1.00 19.03 ? 311 ASN B CG 1 ATOM 5532 O OD1 . ASN B 1 278 ? -49.083 27.249 25.779 1.00 18.74 ? 311 ASN B OD1 1 ATOM 5533 N ND2 . ASN B 1 278 ? -47.954 25.946 27.215 1.00 18.56 ? 311 ASN B ND2 1 ATOM 5534 N N . SER B 1 279 ? -48.135 30.491 28.603 1.00 15.27 ? 312 SER B N 1 ATOM 5535 C CA . SER B 1 279 ? -48.422 31.889 28.330 1.00 16.45 ? 312 SER B CA 1 ATOM 5536 C C . SER B 1 279 ? -48.796 32.094 26.895 1.00 16.41 ? 312 SER B C 1 ATOM 5537 O O . SER B 1 279 ? -48.204 31.472 25.984 1.00 18.91 ? 312 SER B O 1 ATOM 5538 C CB . SER B 1 279 ? -47.149 32.681 28.553 1.00 19.22 ? 312 SER B CB 1 ATOM 5539 O OG . SER B 1 279 ? -46.465 32.195 29.707 1.00 21.45 ? 312 SER B OG 1 ATOM 5540 N N . LEU B 1 280 ? -49.694 33.022 26.638 1.00 15.37 ? 313 LEU B N 1 ATOM 5541 C CA . LEU B 1 280 ? -50.181 33.265 25.264 1.00 14.13 ? 313 LEU B CA 1 ATOM 5542 C C . LEU B 1 280 ? -50.244 34.743 25.068 1.00 12.70 ? 313 LEU B C 1 ATOM 5543 O O . LEU B 1 280 ? -50.592 35.499 25.988 1.00 10.97 ? 313 LEU B O 1 ATOM 5544 C CB . LEU B 1 280 ? -51.586 32.733 25.073 1.00 16.42 ? 313 LEU B CB 1 ATOM 5545 C CG . LEU B 1 280 ? -52.135 31.279 25.312 1.00 17.91 ? 313 LEU B CG 1 ATOM 5546 C CD1 . LEU B 1 280 ? -51.731 30.589 26.622 1.00 18.80 ? 313 LEU B CD1 1 ATOM 5547 C CD2 . LEU B 1 280 ? -53.676 31.315 25.245 1.00 17.26 ? 313 LEU B CD2 1 ATOM 5548 N N . PHE B 1 281 ? -49.871 35.144 23.850 1.00 12.27 ? 314 PHE B N 1 ATOM 5549 C CA . PHE B 1 281 ? -49.688 36.578 23.415 1.00 11.07 ? 314 PHE B CA 1 ATOM 5550 C C . PHE B 1 281 ? -50.475 36.933 22.118 1.00 10.17 ? 314 PHE B C 1 ATOM 5551 O O . PHE B 1 281 ? -50.265 36.393 21.017 1.00 8.76 ? 314 PHE B O 1 ATOM 5552 C CB . PHE B 1 281 ? -48.227 36.962 23.253 1.00 10.97 ? 314 PHE B CB 1 ATOM 5553 C CG . PHE B 1 281 ? -47.414 36.542 24.395 1.00 11.99 ? 314 PHE B CG 1 ATOM 5554 C CD1 . PHE B 1 281 ? -47.163 37.419 25.447 1.00 13.21 ? 314 PHE B CD1 1 ATOM 5555 C CD2 . PHE B 1 281 ? -46.981 35.205 24.503 1.00 11.92 ? 314 PHE B CD2 1 ATOM 5556 C CE1 . PHE B 1 281 ? -46.433 36.973 26.566 1.00 13.56 ? 314 PHE B CE1 1 ATOM 5557 C CE2 . PHE B 1 281 ? -46.281 34.773 25.606 1.00 12.53 ? 314 PHE B CE2 1 ATOM 5558 C CZ . PHE B 1 281 ? -45.970 35.643 26.626 1.00 12.65 ? 314 PHE B CZ 1 ATOM 5559 N N . VAL B 1 282 ? -51.418 37.852 22.345 1.00 9.60 ? 315 VAL B N 1 ATOM 5560 C CA . VAL B 1 282 ? -52.176 38.526 21.298 1.00 8.72 ? 315 VAL B CA 1 ATOM 5561 C C . VAL B 1 282 ? -51.488 39.833 20.959 1.00 7.25 ? 315 VAL B C 1 ATOM 5562 O O . VAL B 1 282 ? -51.367 40.763 21.773 1.00 6.20 ? 315 VAL B O 1 ATOM 5563 C CB . VAL B 1 282 ? -53.620 38.846 21.806 1.00 9.10 ? 315 VAL B CB 1 ATOM 5564 C CG1 . VAL B 1 282 ? -54.476 39.363 20.635 1.00 9.16 ? 315 VAL B CG1 1 ATOM 5565 C CG2 . VAL B 1 282 ? -54.204 37.652 22.554 1.00 8.97 ? 315 VAL B CG2 1 ATOM 5566 N N . ALA B 1 283 ? -51.090 39.924 19.739 1.00 6.75 ? 316 ALA B N 1 ATOM 5567 C CA . ALA B 1 283 ? -50.399 41.102 19.362 1.00 6.88 ? 316 ALA B CA 1 ATOM 5568 C C . ALA B 1 283 ? -51.355 41.996 18.641 1.00 7.28 ? 316 ALA B C 1 ATOM 5569 O O . ALA B 1 283 ? -52.256 41.531 17.966 1.00 7.72 ? 316 ALA B O 1 ATOM 5570 C CB . ALA B 1 283 ? -49.194 40.749 18.576 1.00 6.63 ? 316 ALA B CB 1 ATOM 5571 N N . PRO B 1 284 ? -51.233 43.292 18.822 1.00 7.92 ? 317 PRO B N 1 ATOM 5572 C CA . PRO B 1 284 ? -52.173 44.200 18.081 1.00 8.80 ? 317 PRO B CA 1 ATOM 5573 C C . PRO B 1 284 ? -51.997 44.335 16.502 1.00 8.59 ? 317 PRO B C 1 ATOM 5574 O O . PRO B 1 284 ? -51.003 43.917 15.907 1.00 8.52 ? 317 PRO B O 1 ATOM 5575 C CB . PRO B 1 284 ? -52.013 45.570 18.868 1.00 8.79 ? 317 PRO B CB 1 ATOM 5576 C CG . PRO B 1 284 ? -50.600 45.535 19.351 1.00 8.79 ? 317 PRO B CG 1 ATOM 5577 C CD . PRO B 1 284 ? -50.261 44.044 19.629 1.00 8.52 ? 317 PRO B CD 1 ATOM 5578 N N . ALA B 1 285 ? -52.929 44.958 15.834 1.00 8.94 ? 318 ALA B N 1 ATOM 5579 C CA . ALA B 1 285 ? -52.820 45.103 14.357 1.00 8.96 ? 318 ALA B CA 1 ATOM 5580 C C . ALA B 1 285 ? -51.926 46.227 14.042 1.00 10.46 ? 318 ALA B C 1 ATOM 5581 O O . ALA B 1 285 ? -51.715 47.142 14.861 1.00 11.30 ? 318 ALA B O 1 ATOM 5582 C CB . ALA B 1 285 ? -54.161 45.408 13.749 1.00 8.83 ? 318 ALA B CB 1 ATOM 5583 N N . VAL B 1 286 ? -51.350 46.179 12.837 1.00 11.92 ? 319 VAL B N 1 ATOM 5584 C CA . VAL B 1 286 ? -50.760 47.349 12.192 1.00 12.16 ? 319 VAL B CA 1 ATOM 5585 C C . VAL B 1 286 ? -51.886 48.302 11.748 1.00 13.50 ? 319 VAL B C 1 ATOM 5586 O O . VAL B 1 286 ? -51.825 49.551 11.946 1.00 15.27 ? 319 VAL B O 1 ATOM 5587 C CB . VAL B 1 286 ? -49.894 46.929 11.022 1.00 12.54 ? 319 VAL B CB 1 ATOM 5588 C CG1 . VAL B 1 286 ? -49.856 48.017 9.985 1.00 12.55 ? 319 VAL B CG1 1 ATOM 5589 C CG2 . VAL B 1 286 ? -48.466 46.558 11.466 1.00 12.72 ? 319 VAL B CG2 1 ATOM 5590 N N . THR B 1 287 ? -52.971 47.763 11.192 1.00 14.41 ? 320 THR B N 1 ATOM 5591 C CA . THR B 1 287 ? -54.082 48.684 10.857 1.00 14.46 ? 320 THR B CA 1 ATOM 5592 C C . THR B 1 287 ? -54.593 49.325 12.197 1.00 15.61 ? 320 THR B C 1 ATOM 5593 O O . THR B 1 287 ? -54.593 48.719 13.267 1.00 17.67 ? 320 THR B O 1 ATOM 5594 C CB . THR B 1 287 ? -55.214 47.921 10.112 1.00 14.40 ? 320 THR B CB 1 ATOM 5595 O OG1 . THR B 1 287 ? -56.197 48.855 9.562 1.00 12.37 ? 320 THR B OG1 1 ATOM 5596 C CG2 . THR B 1 287 ? -55.847 46.898 11.124 1.00 14.29 ? 320 THR B CG2 1 ATOM 5597 N N . PRO B 1 288 ? -55.139 50.501 12.139 1.00 15.21 ? 321 PRO B N 1 ATOM 5598 C CA . PRO B 1 288 ? -55.796 51.106 13.259 1.00 14.27 ? 321 PRO B CA 1 ATOM 5599 C C . PRO B 1 288 ? -57.271 51.261 13.101 1.00 14.15 ? 321 PRO B C 1 ATOM 5600 O O . PRO B 1 288 ? -57.902 51.981 13.858 1.00 13.34 ? 321 PRO B O 1 ATOM 5601 C CB . PRO B 1 288 ? -55.270 52.510 13.171 1.00 15.61 ? 321 PRO B CB 1 ATOM 5602 C CG . PRO B 1 288 ? -55.081 52.736 11.719 1.00 15.41 ? 321 PRO B CG 1 ATOM 5603 C CD . PRO B 1 288 ? -54.512 51.473 11.237 1.00 15.85 ? 321 PRO B CD 1 ATOM 5604 N N . VAL B 1 289 ? -57.840 50.617 12.125 1.00 15.28 ? 322 VAL B N 1 ATOM 5605 C CA . VAL B 1 289 ? -59.178 51.041 11.700 1.00 16.12 ? 322 VAL B CA 1 ATOM 5606 C C . VAL B 1 289 ? -60.111 50.853 12.851 1.00 15.89 ? 322 VAL B C 1 ATOM 5607 O O . VAL B 1 289 ? -59.922 49.939 13.605 1.00 17.60 ? 322 VAL B O 1 ATOM 5608 C CB . VAL B 1 289 ? -59.760 50.234 10.505 1.00 16.05 ? 322 VAL B CB 1 ATOM 5609 C CG1 . VAL B 1 289 ? -59.931 48.759 10.904 1.00 16.19 ? 322 VAL B CG1 1 ATOM 5610 C CG2 . VAL B 1 289 ? -61.088 50.857 10.040 1.00 14.86 ? 322 VAL B CG2 1 ATOM 5611 N N . LYS B 1 290 ? -61.108 51.710 12.948 1.00 15.38 ? 323 LYS B N 1 ATOM 5612 C CA . LYS B 1 290 ? -62.264 51.498 13.809 1.00 14.64 ? 323 LYS B CA 1 ATOM 5613 C C . LYS B 1 290 ? -63.627 51.831 13.135 1.00 13.99 ? 323 LYS B C 1 ATOM 5614 O O . LYS B 1 290 ? -63.736 52.518 12.113 1.00 13.57 ? 323 LYS B O 1 ATOM 5615 C CB . LYS B 1 290 ? -62.102 52.334 15.111 1.00 14.29 ? 323 LYS B CB 1 ATOM 5616 C CG . LYS B 1 290 ? -61.969 53.853 14.981 1.00 13.47 ? 323 LYS B CG 1 ATOM 5617 C CD . LYS B 1 290 ? -61.568 54.398 16.312 1.00 13.82 ? 323 LYS B CD 1 ATOM 5618 C CE . LYS B 1 290 ? -61.867 55.834 16.585 1.00 14.42 ? 323 LYS B CE 1 ATOM 5619 N NZ . LYS B 1 290 ? -63.304 56.106 16.561 1.00 15.16 1 323 LYS B NZ 1 ATOM 5620 N N . SER B 1 291 ? -64.655 51.354 13.785 1.00 14.16 ? 324 SER B N 1 ATOM 5621 C CA A SER B 1 291 ? -66.003 51.812 13.499 0.50 15.94 ? 324 SER B CA 1 ATOM 5622 C CA B SER B 1 291 ? -66.020 51.814 13.540 0.50 15.53 ? 324 SER B CA 1 ATOM 5623 C C . SER B 1 291 ? -66.196 53.262 13.990 1.00 16.75 ? 324 SER B C 1 ATOM 5624 O O . SER B 1 291 ? -65.631 53.652 15.066 1.00 17.44 ? 324 SER B O 1 ATOM 5625 C CB A SER B 1 291 ? -67.029 50.873 14.150 0.50 15.88 ? 324 SER B CB 1 ATOM 5626 C CB B SER B 1 291 ? -67.034 50.964 14.317 0.50 15.01 ? 324 SER B CB 1 ATOM 5627 O OG A SER B 1 291 ? -66.949 49.573 13.571 0.50 15.92 ? 324 SER B OG 1 ATOM 5628 O OG B SER B 1 291 ? -67.980 51.792 14.961 0.50 14.16 ? 324 SER B OG 1 ATOM 5629 N N . VAL B 1 292 ? -66.979 54.059 13.226 1.00 16.51 ? 325 VAL B N 1 ATOM 5630 C CA . VAL B 1 292 ? -67.309 55.426 13.714 1.00 18.42 ? 325 VAL B CA 1 ATOM 5631 C C . VAL B 1 292 ? -67.772 55.464 15.196 1.00 21.68 ? 325 VAL B C 1 ATOM 5632 O O . VAL B 1 292 ? -67.467 56.447 15.876 1.00 25.67 ? 325 VAL B O 1 ATOM 5633 C CB . VAL B 1 292 ? -68.388 56.252 12.943 1.00 16.94 ? 325 VAL B CB 1 ATOM 5634 C CG1 . VAL B 1 292 ? -68.278 57.694 13.412 1.00 16.60 ? 325 VAL B CG1 1 ATOM 5635 C CG2 . VAL B 1 292 ? -68.287 56.200 11.415 1.00 16.77 ? 325 VAL B CG2 1 ATOM 5636 N N . LEU B 1 293 ? -68.511 54.451 15.693 1.00 22.85 ? 326 LEU B N 1 ATOM 5637 C CA . LEU B 1 293 ? -69.076 54.509 17.079 1.00 23.90 ? 326 LEU B CA 1 ATOM 5638 C C . LEU B 1 293 ? -68.142 54.187 18.260 1.00 24.09 ? 326 LEU B C 1 ATOM 5639 O O . LEU B 1 293 ? -68.453 54.535 19.421 1.00 22.25 ? 326 LEU B O 1 ATOM 5640 C CB . LEU B 1 293 ? -70.381 53.695 17.173 1.00 23.67 ? 326 LEU B CB 1 ATOM 5641 C CG . LEU B 1 293 ? -71.442 54.316 16.247 1.00 25.69 ? 326 LEU B CG 1 ATOM 5642 C CD1 . LEU B 1 293 ? -72.684 53.419 16.209 1.00 29.75 ? 326 LEU B CD1 1 ATOM 5643 C CD2 . LEU B 1 293 ? -71.837 55.777 16.576 1.00 23.91 ? 326 LEU B CD2 1 ATOM 5644 N N . GLU B 1 294 ? -67.004 53.547 17.963 1.00 24.30 ? 327 GLU B N 1 ATOM 5645 C CA . GLU B 1 294 ? -65.992 53.215 18.994 1.00 23.56 ? 327 GLU B CA 1 ATOM 5646 C C . GLU B 1 294 ? -65.219 54.465 19.507 1.00 21.45 ? 327 GLU B C 1 ATOM 5647 O O . GLU B 1 294 ? -64.616 55.264 18.733 1.00 16.27 ? 327 GLU B O 1 ATOM 5648 C CB . GLU B 1 294 ? -65.026 52.126 18.479 1.00 24.40 ? 327 GLU B CB 1 ATOM 5649 C CG . GLU B 1 294 ? -65.812 50.837 18.182 1.00 27.43 ? 327 GLU B CG 1 ATOM 5650 C CD . GLU B 1 294 ? -65.143 49.832 17.258 1.00 27.55 ? 327 GLU B CD 1 ATOM 5651 O OE1 . GLU B 1 294 ? -65.268 48.652 17.543 1.00 35.05 ? 327 GLU B OE1 1 ATOM 5652 O OE2 . GLU B 1 294 ? -64.523 50.167 16.245 1.00 28.45 -1 327 GLU B OE2 1 ATOM 5653 N N . LYS B 1 295 ? -65.207 54.609 20.836 1.00 19.25 ? 328 LYS B N 1 ATOM 5654 C CA . LYS B 1 295 ? -64.278 55.576 21.411 1.00 19.63 ? 328 LYS B CA 1 ATOM 5655 C C . LYS B 1 295 ? -62.809 55.244 21.102 1.00 19.61 ? 328 LYS B C 1 ATOM 5656 O O . LYS B 1 295 ? -62.041 56.128 20.737 1.00 19.59 ? 328 LYS B O 1 ATOM 5657 C CB . LYS B 1 295 ? -64.436 55.720 22.925 1.00 20.41 ? 328 LYS B CB 1 ATOM 5658 C CG . LYS B 1 295 ? -63.304 56.483 23.570 1.00 21.00 ? 328 LYS B CG 1 ATOM 5659 C CD . LYS B 1 295 ? -63.355 57.929 23.099 1.00 23.97 ? 328 LYS B CD 1 ATOM 5660 C CE . LYS B 1 295 ? -62.214 58.737 23.742 1.00 26.18 ? 328 LYS B CE 1 ATOM 5661 N NZ . LYS B 1 295 ? -60.906 58.545 23.010 1.00 27.75 1 328 LYS B NZ 1 ATOM 5662 N N . GLN B 1 296 ? -62.418 53.984 21.311 1.00 19.32 ? 329 GLN B N 1 ATOM 5663 C CA . GLN B 1 296 ? -61.058 53.566 21.147 1.00 18.86 ? 329 GLN B CA 1 ATOM 5664 C C . GLN B 1 296 ? -60.762 52.691 19.889 1.00 17.20 ? 329 GLN B C 1 ATOM 5665 O O . GLN B 1 296 ? -61.576 51.892 19.477 1.00 16.27 ? 329 GLN B O 1 ATOM 5666 C CB . GLN B 1 296 ? -60.715 52.773 22.395 1.00 19.89 ? 329 GLN B CB 1 ATOM 5667 C CG . GLN B 1 296 ? -60.682 53.618 23.640 1.00 21.61 ? 329 GLN B CG 1 ATOM 5668 C CD . GLN B 1 296 ? -59.504 54.574 23.652 1.00 22.25 ? 329 GLN B CD 1 ATOM 5669 O OE1 . GLN B 1 296 ? -59.688 55.784 23.530 1.00 22.43 ? 329 GLN B OE1 1 ATOM 5670 N NE2 . GLN B 1 296 ? -58.277 54.032 23.756 1.00 21.71 ? 329 GLN B NE2 1 ATOM 5671 N N . THR B 1 297 ? -59.555 52.855 19.360 1.00 14.97 ? 330 THR B N 1 ATOM 5672 C CA . THR B 1 297 ? -58.857 51.865 18.483 1.00 13.11 ? 330 THR B CA 1 ATOM 5673 C C . THR B 1 297 ? -57.470 51.645 19.103 1.00 11.62 ? 330 THR B C 1 ATOM 5674 O O . THR B 1 297 ? -57.100 52.242 20.096 1.00 10.96 ? 330 THR B O 1 ATOM 5675 C CB . THR B 1 297 ? -58.738 52.473 17.032 1.00 13.13 ? 330 THR B CB 1 ATOM 5676 O OG1 . THR B 1 297 ? -58.397 51.510 16.058 1.00 12.20 ? 330 THR B OG1 1 ATOM 5677 C CG2 . THR B 1 297 ? -57.741 53.810 16.913 1.00 13.00 ? 330 THR B CG2 1 ATOM 5678 N N . ASN B 1 298 ? -56.690 50.840 18.450 1.00 10.69 ? 331 ASN B N 1 ATOM 5679 C CA . ASN B 1 298 ? -55.253 50.731 18.699 1.00 9.94 ? 331 ASN B CA 1 ATOM 5680 C C . ASN B 1 298 ? -54.510 51.630 17.748 1.00 10.55 ? 331 ASN B C 1 ATOM 5681 O O . ASN B 1 298 ? -54.912 51.811 16.627 1.00 9.93 ? 331 ASN B O 1 ATOM 5682 C CB . ASN B 1 298 ? -54.800 49.276 18.430 1.00 9.08 ? 331 ASN B CB 1 ATOM 5683 C CG . ASN B 1 298 ? -55.041 48.818 16.941 1.00 8.80 ? 331 ASN B CG 1 ATOM 5684 O OD1 . ASN B 1 298 ? -56.164 48.724 16.414 1.00 7.69 ? 331 ASN B OD1 1 ATOM 5685 N ND2 . ASN B 1 298 ? -53.967 48.579 16.263 1.00 8.92 ? 331 ASN B ND2 1 ATOM 5686 N N . ASN B 1 299 ? -53.376 52.155 18.174 1.00 12.89 ? 332 ASN B N 1 ATOM 5687 C CA . ASN B 1 299 ? -52.334 52.726 17.269 1.00 14.29 ? 332 ASN B CA 1 ATOM 5688 C C . ASN B 1 299 ? -51.646 51.556 16.562 1.00 14.02 ? 332 ASN B C 1 ATOM 5689 O O . ASN B 1 299 ? -51.685 50.467 17.072 1.00 13.00 ? 332 ASN B O 1 ATOM 5690 C CB . ASN B 1 299 ? -51.240 53.482 18.076 1.00 16.04 ? 332 ASN B CB 1 ATOM 5691 C CG . ASN B 1 299 ? -51.509 54.990 18.272 1.00 17.42 ? 332 ASN B CG 1 ATOM 5692 O OD1 . ASN B 1 299 ? -51.255 55.537 19.359 1.00 20.07 ? 332 ASN B OD1 1 ATOM 5693 N ND2 . ASN B 1 299 ? -51.932 55.667 17.230 1.00 18.81 ? 332 ASN B ND2 1 ATOM 5694 N N . PRO B 1 300 ? -50.958 51.784 15.423 1.00 14.67 ? 333 PRO B N 1 ATOM 5695 C CA . PRO B 1 300 ? -50.257 50.670 14.794 1.00 15.35 ? 333 PRO B CA 1 ATOM 5696 C C . PRO B 1 300 ? -49.153 50.057 15.640 1.00 16.23 ? 333 PRO B C 1 ATOM 5697 O O . PRO B 1 300 ? -48.379 50.801 16.231 1.00 15.48 ? 333 PRO B O 1 ATOM 5698 C CB . PRO B 1 300 ? -49.619 51.317 13.557 1.00 15.47 ? 333 PRO B CB 1 ATOM 5699 C CG . PRO B 1 300 ? -50.592 52.349 13.211 1.00 15.16 ? 333 PRO B CG 1 ATOM 5700 C CD . PRO B 1 300 ? -51.068 52.922 14.509 1.00 14.60 ? 333 PRO B CD 1 ATOM 5701 N N . GLY B 1 301 ? -49.067 48.718 15.638 1.00 17.52 ? 334 GLY B N 1 ATOM 5702 C CA . GLY B 1 301 ? -48.020 48.008 16.371 1.00 17.63 ? 334 GLY B CA 1 ATOM 5703 C C . GLY B 1 301 ? -47.290 46.882 15.646 1.00 18.12 ? 334 GLY B C 1 ATOM 5704 O O . GLY B 1 301 ? -47.880 46.189 14.818 1.00 16.27 ? 334 GLY B O 1 ATOM 5705 N N . ILE B 1 302 ? -46.008 46.703 16.009 1.00 20.52 ? 335 ILE B N 1 ATOM 5706 C CA . ILE B 1 302 ? -45.121 45.594 15.573 1.00 22.04 ? 335 ILE B CA 1 ATOM 5707 C C . ILE B 1 302 ? -44.433 45.103 16.861 1.00 20.40 ? 335 ILE B C 1 ATOM 5708 O O . ILE B 1 302 ? -44.155 45.896 17.745 1.00 18.69 ? 335 ILE B O 1 ATOM 5709 C CB . ILE B 1 302 ? -44.034 46.115 14.569 1.00 28.78 ? 335 ILE B CB 1 ATOM 5710 C CG1 . ILE B 1 302 ? -44.690 46.793 13.350 1.00 30.48 ? 335 ILE B CG1 1 ATOM 5711 C CG2 . ILE B 1 302 ? -43.104 44.999 14.074 1.00 30.24 ? 335 ILE B CG2 1 ATOM 5712 C CD1 . ILE B 1 302 ? -45.314 45.756 12.439 1.00 31.92 ? 335 ILE B CD1 1 ATOM 5713 N N . ARG B 1 303 ? -44.160 43.807 16.989 1.00 19.99 ? 336 ARG B N 1 ATOM 5714 C CA . ARG B 1 303 ? -43.509 43.281 18.190 1.00 18.50 ? 336 ARG B CA 1 ATOM 5715 C C . ARG B 1 303 ? -42.336 42.289 17.971 1.00 20.62 ? 336 ARG B C 1 ATOM 5716 O O . ARG B 1 303 ? -42.228 41.569 16.947 1.00 20.53 ? 336 ARG B O 1 ATOM 5717 C CB . ARG B 1 303 ? -44.533 42.694 19.143 1.00 16.69 ? 336 ARG B CB 1 ATOM 5718 C CG . ARG B 1 303 ? -45.233 41.419 18.708 1.00 15.62 ? 336 ARG B CG 1 ATOM 5719 C CD . ARG B 1 303 ? -45.929 40.755 19.877 1.00 15.08 ? 336 ARG B CD 1 ATOM 5720 N NE . ARG B 1 303 ? -46.744 41.720 20.550 1.00 16.78 ? 336 ARG B NE 1 ATOM 5721 C CZ . ARG B 1 303 ? -47.637 41.490 21.521 1.00 18.83 ? 336 ARG B CZ 1 ATOM 5722 N NH1 . ARG B 1 303 ? -47.970 40.265 21.934 1.00 20.60 1 336 ARG B NH1 1 ATOM 5723 N NH2 . ARG B 1 303 ? -48.274 42.512 22.071 1.00 19.08 ? 336 ARG B NH2 1 ATOM 5724 N N . LEU B 1 304 ? -41.467 42.267 18.983 1.00 21.62 ? 337 LEU B N 1 ATOM 5725 C CA . LEU B 1 304 ? -40.234 41.514 18.974 1.00 21.44 ? 337 LEU B CA 1 ATOM 5726 C C . LEU B 1 304 ? -40.047 40.754 20.266 1.00 18.80 ? 337 LEU B C 1 ATOM 5727 O O . LEU B 1 304 ? -39.831 41.353 21.294 1.00 20.04 ? 337 LEU B O 1 ATOM 5728 C CB . LEU B 1 304 ? -39.080 42.485 18.808 1.00 24.71 ? 337 LEU B CB 1 ATOM 5729 C CG . LEU B 1 304 ? -37.680 41.868 18.967 1.00 25.20 ? 337 LEU B CG 1 ATOM 5730 C CD1 . LEU B 1 304 ? -37.191 41.444 17.592 1.00 25.49 ? 337 LEU B CD1 1 ATOM 5731 C CD2 . LEU B 1 304 ? -36.739 42.871 19.579 1.00 26.63 ? 337 LEU B CD2 1 ATOM 5732 N N . PHE B 1 305 ? -40.077 39.442 20.172 1.00 17.97 ? 338 PHE B N 1 ATOM 5733 C CA . PHE B 1 305 ? -39.970 38.510 21.288 1.00 18.76 ? 338 PHE B CA 1 ATOM 5734 C C . PHE B 1 305 ? -38.520 38.019 21.397 1.00 20.95 ? 338 PHE B C 1 ATOM 5735 O O . PHE B 1 305 ? -37.829 37.796 20.347 1.00 20.71 ? 338 PHE B O 1 ATOM 5736 C CB . PHE B 1 305 ? -40.857 37.285 21.015 1.00 18.60 ? 338 PHE B CB 1 ATOM 5737 C CG . PHE B 1 305 ? -42.307 37.512 21.287 1.00 18.69 ? 338 PHE B CG 1 ATOM 5738 C CD1 . PHE B 1 305 ? -42.791 37.469 22.555 1.00 19.36 ? 338 PHE B CD1 1 ATOM 5739 C CD2 . PHE B 1 305 ? -43.193 37.712 20.277 1.00 21.51 ? 338 PHE B CD2 1 ATOM 5740 C CE1 . PHE B 1 305 ? -44.121 37.676 22.841 1.00 20.10 ? 338 PHE B CE1 1 ATOM 5741 C CE2 . PHE B 1 305 ? -44.551 37.928 20.549 1.00 22.27 ? 338 PHE B CE2 1 ATOM 5742 C CZ . PHE B 1 305 ? -45.004 37.920 21.845 1.00 21.96 ? 338 PHE B CZ 1 ATOM 5743 N N . GLN B 1 306 ? -38.033 37.861 22.636 1.00 21.69 ? 339 GLN B N 1 ATOM 5744 C CA . GLN B 1 306 ? -36.658 37.332 22.860 1.00 21.95 ? 339 GLN B CA 1 ATOM 5745 C C . GLN B 1 306 ? -36.857 36.035 23.477 1.00 20.09 ? 339 GLN B C 1 ATOM 5746 O O . GLN B 1 306 ? -37.770 35.897 24.301 1.00 21.01 ? 339 GLN B O 1 ATOM 5747 C CB . GLN B 1 306 ? -35.830 38.152 23.826 1.00 26.38 ? 339 GLN B CB 1 ATOM 5748 C CG . GLN B 1 306 ? -35.845 39.652 23.497 1.00 28.51 ? 339 GLN B CG 1 ATOM 5749 C CD . GLN B 1 306 ? -34.786 40.420 24.230 1.00 28.54 ? 339 GLN B CD 1 ATOM 5750 O OE1 . GLN B 1 306 ? -34.698 40.410 25.458 1.00 31.47 ? 339 GLN B OE1 1 ATOM 5751 N NE2 . GLN B 1 306 ? -33.974 41.086 23.477 1.00 28.20 ? 339 GLN B NE2 1 ATOM 5752 N N . TYR B 1 307 ? -36.040 35.072 23.051 1.00 18.37 ? 340 TYR B N 1 ATOM 5753 C CA . TYR B 1 307 ? -36.115 33.667 23.536 1.00 17.63 ? 340 TYR B CA 1 ATOM 5754 C C . TYR B 1 307 ? -34.708 33.063 23.828 1.00 16.22 ? 340 TYR B C 1 ATOM 5755 O O . TYR B 1 307 ? -33.706 33.437 23.192 1.00 14.71 ? 340 TYR B O 1 ATOM 5756 C CB . TYR B 1 307 ? -36.937 32.766 22.557 1.00 17.63 ? 340 TYR B CB 1 ATOM 5757 C CG . TYR B 1 307 ? -36.299 32.624 21.207 1.00 19.43 ? 340 TYR B CG 1 ATOM 5758 C CD1 . TYR B 1 307 ? -36.452 33.629 20.205 1.00 21.25 ? 340 TYR B CD1 1 ATOM 5759 C CD2 . TYR B 1 307 ? -35.471 31.521 20.917 1.00 20.03 ? 340 TYR B CD2 1 ATOM 5760 C CE1 . TYR B 1 307 ? -35.831 33.507 18.957 1.00 20.28 ? 340 TYR B CE1 1 ATOM 5761 C CE2 . TYR B 1 307 ? -34.868 31.392 19.676 1.00 20.61 ? 340 TYR B CE2 1 ATOM 5762 C CZ . TYR B 1 307 ? -35.058 32.389 18.715 1.00 20.22 ? 340 TYR B CZ 1 ATOM 5763 O OH . TYR B 1 307 ? -34.473 32.224 17.519 1.00 22.06 ? 340 TYR B OH 1 ATOM 5764 N N . ASP B 1 308 ? -34.682 32.142 24.790 1.00 15.99 ? 341 ASP B N 1 ATOM 5765 C CA . ASP B 1 308 ? -33.521 31.361 25.127 1.00 17.55 ? 341 ASP B CA 1 ATOM 5766 C C . ASP B 1 308 ? -33.238 30.297 24.000 1.00 18.41 ? 341 ASP B C 1 ATOM 5767 O O . ASP B 1 308 ? -34.047 29.417 23.746 1.00 19.89 ? 341 ASP B O 1 ATOM 5768 C CB . ASP B 1 308 ? -33.743 30.715 26.533 1.00 18.41 ? 341 ASP B CB 1 ATOM 5769 C CG . ASP B 1 308 ? -32.391 30.235 27.233 1.00 19.10 ? 341 ASP B CG 1 ATOM 5770 O OD1 . ASP B 1 308 ? -31.530 29.702 26.489 1.00 16.73 ? 341 ASP B OD1 1 ATOM 5771 O OD2 . ASP B 1 308 ? -32.229 30.377 28.523 1.00 20.15 -1 341 ASP B OD2 1 ATOM 5772 N N . PRO B 1 309 ? -32.089 30.373 23.324 1.00 18.22 ? 342 PRO B N 1 ATOM 5773 C CA . PRO B 1 309 ? -31.929 29.414 22.209 1.00 19.60 ? 342 PRO B CA 1 ATOM 5774 C C . PRO B 1 309 ? -31.767 27.956 22.583 1.00 21.12 ? 342 PRO B C 1 ATOM 5775 O O . PRO B 1 309 ? -31.775 27.113 21.681 1.00 18.90 ? 342 PRO B O 1 ATOM 5776 C CB . PRO B 1 309 ? -30.665 29.881 21.509 1.00 20.24 ? 342 PRO B CB 1 ATOM 5777 C CG . PRO B 1 309 ? -30.524 31.363 21.924 1.00 20.26 ? 342 PRO B CG 1 ATOM 5778 C CD . PRO B 1 309 ? -31.055 31.430 23.328 1.00 18.80 ? 342 PRO B CD 1 ATOM 5779 N N . ARG B 1 310 ? -31.654 27.668 23.896 1.00 23.92 ? 343 ARG B N 1 ATOM 5780 C CA . ARG B 1 310 ? -31.458 26.268 24.398 1.00 24.38 ? 343 ARG B CA 1 ATOM 5781 C C . ARG B 1 310 ? -32.756 25.511 24.613 1.00 23.05 ? 343 ARG B C 1 ATOM 5782 O O . ARG B 1 310 ? -32.959 24.467 24.026 1.00 23.90 ? 343 ARG B O 1 ATOM 5783 C CB . ARG B 1 310 ? -30.647 26.229 25.695 1.00 24.37 ? 343 ARG B CB 1 ATOM 5784 C CG . ARG B 1 310 ? -29.238 26.727 25.485 1.00 25.96 ? 343 ARG B CG 1 ATOM 5785 C CD . ARG B 1 310 ? -28.557 27.076 26.790 1.00 27.20 ? 343 ARG B CD 1 ATOM 5786 N NE . ARG B 1 310 ? -29.328 28.082 27.496 1.00 29.35 ? 343 ARG B NE 1 ATOM 5787 C CZ . ARG B 1 310 ? -28.972 28.653 28.639 1.00 28.34 ? 343 ARG B CZ 1 ATOM 5788 N NH1 . ARG B 1 310 ? -27.827 28.336 29.240 1.00 28.30 1 343 ARG B NH1 1 ATOM 5789 N NH2 . ARG B 1 310 ? -29.777 29.559 29.161 1.00 27.90 ? 343 ARG B NH2 1 ATOM 5790 N N . ASP B 1 311 ? -33.624 26.042 25.468 1.00 22.03 ? 344 ASP B N 1 ATOM 5791 C CA . ASP B 1 311 ? -34.936 25.428 25.723 1.00 20.83 ? 344 ASP B CA 1 ATOM 5792 C C . ASP B 1 311 ? -36.151 26.149 24.992 1.00 20.28 ? 344 ASP B C 1 ATOM 5793 O O . ASP B 1 311 ? -37.287 25.675 25.016 1.00 18.74 ? 344 ASP B O 1 ATOM 5794 C CB . ASP B 1 311 ? -35.133 25.301 27.220 1.00 17.86 ? 344 ASP B CB 1 ATOM 5795 C CG . ASP B 1 311 ? -35.247 26.586 27.858 1.00 19.06 ? 344 ASP B CG 1 ATOM 5796 O OD1 . ASP B 1 311 ? -35.083 27.630 27.218 1.00 15.89 ? 344 ASP B OD1 1 ATOM 5797 O OD2 . ASP B 1 311 ? -35.541 26.579 29.051 1.00 27.25 -1 344 ASP B OD2 1 ATOM 5798 N N . TYR B 1 312 ? -35.877 27.274 24.329 1.00 20.94 ? 345 TYR B N 1 ATOM 5799 C CA . TYR B 1 312 ? -36.925 28.124 23.682 1.00 22.65 ? 345 TYR B CA 1 ATOM 5800 C C . TYR B 1 312 ? -37.925 28.801 24.616 1.00 21.53 ? 345 TYR B C 1 ATOM 5801 O O . TYR B 1 312 ? -38.963 29.207 24.184 1.00 20.86 ? 345 TYR B O 1 ATOM 5802 C CB . TYR B 1 312 ? -37.597 27.391 22.490 1.00 24.64 ? 345 TYR B CB 1 ATOM 5803 C CG . TYR B 1 312 ? -36.507 26.899 21.560 1.00 27.09 ? 345 TYR B CG 1 ATOM 5804 C CD1 . TYR B 1 312 ? -35.897 27.774 20.660 1.00 28.13 ? 345 TYR B CD1 1 ATOM 5805 C CD2 . TYR B 1 312 ? -35.946 25.605 21.706 1.00 28.67 ? 345 TYR B CD2 1 ATOM 5806 C CE1 . TYR B 1 312 ? -34.829 27.346 19.877 1.00 30.00 ? 345 TYR B CE1 1 ATOM 5807 C CE2 . TYR B 1 312 ? -34.881 25.183 20.920 1.00 28.98 ? 345 TYR B CE2 1 ATOM 5808 C CZ . TYR B 1 312 ? -34.352 26.057 20.004 1.00 28.38 ? 345 TYR B CZ 1 ATOM 5809 O OH . TYR B 1 312 ? -33.332 25.663 19.235 1.00 29.61 ? 345 TYR B OH 1 ATOM 5810 N N . LYS B 1 313 ? -37.547 28.948 25.877 1.00 22.79 ? 346 LYS B N 1 ATOM 5811 C CA . LYS B 1 313 ? -38.177 29.823 26.886 1.00 27.29 ? 346 LYS B CA 1 ATOM 5812 C C . LYS B 1 313 ? -38.280 31.306 26.403 1.00 24.20 ? 346 LYS B C 1 ATOM 5813 O O . LYS B 1 313 ? -37.263 31.883 25.898 1.00 21.98 ? 346 LYS B O 1 ATOM 5814 C CB . LYS B 1 313 ? -37.270 29.725 28.154 1.00 35.36 ? 346 LYS B CB 1 ATOM 5815 C CG . LYS B 1 313 ? -37.790 30.145 29.552 1.00 41.51 ? 346 LYS B CG 1 ATOM 5816 C CD . LYS B 1 313 ? -36.945 29.478 30.673 1.00 43.41 ? 346 LYS B CD 1 ATOM 5817 C CE . LYS B 1 313 ? -35.544 30.099 30.882 1.00 45.17 ? 346 LYS B CE 1 ATOM 5818 N NZ . LYS B 1 313 ? -34.314 29.359 30.394 1.00 41.49 1 346 LYS B NZ 1 ATOM 5819 N N . LEU B 1 314 ? -39.461 31.926 26.548 1.00 21.80 ? 347 LEU B N 1 ATOM 5820 C CA . LEU B 1 314 ? -39.604 33.425 26.266 1.00 21.95 ? 347 LEU B CA 1 ATOM 5821 C C . LEU B 1 314 ? -38.976 34.316 27.380 1.00 20.37 ? 347 LEU B C 1 ATOM 5822 O O . LEU B 1 314 ? -39.404 34.247 28.543 1.00 19.48 ? 347 LEU B O 1 ATOM 5823 C CB . LEU B 1 314 ? -41.054 33.870 26.003 1.00 21.16 ? 347 LEU B CB 1 ATOM 5824 C CG . LEU B 1 314 ? -41.577 33.094 24.821 1.00 24.70 ? 347 LEU B CG 1 ATOM 5825 C CD1 . LEU B 1 314 ? -43.099 33.057 24.792 1.00 24.26 ? 347 LEU B CD1 1 ATOM 5826 C CD2 . LEU B 1 314 ? -40.963 33.614 23.507 1.00 26.11 ? 347 LEU B CD2 1 ATOM 5827 N N . LEU B 1 315 ? -37.974 35.122 27.008 1.00 18.86 ? 348 LEU B N 1 ATOM 5828 C CA . LEU B 1 315 ? -37.273 36.022 27.952 1.00 19.96 ? 348 LEU B CA 1 ATOM 5829 C C . LEU B 1 315 ? -37.889 37.405 28.014 1.00 16.60 ? 348 LEU B C 1 ATOM 5830 O O . LEU B 1 315 ? -37.920 38.025 29.049 1.00 14.39 ? 348 LEU B O 1 ATOM 5831 C CB . LEU B 1 315 ? -35.779 36.165 27.569 1.00 21.28 ? 348 LEU B CB 1 ATOM 5832 C CG . LEU B 1 315 ? -34.984 34.878 27.528 1.00 21.90 ? 348 LEU B CG 1 ATOM 5833 C CD1 . LEU B 1 315 ? -33.618 35.300 27.001 1.00 20.41 ? 348 LEU B CD1 1 ATOM 5834 C CD2 . LEU B 1 315 ? -35.012 34.230 28.963 1.00 22.90 ? 348 LEU B CD2 1 ATOM 5835 N N . ASP B 1 316 ? -38.320 37.881 26.867 1.00 15.57 ? 349 ASP B N 1 ATOM 5836 C CA . ASP B 1 316 ? -38.987 39.115 26.824 1.00 15.68 ? 349 ASP B CA 1 ATOM 5837 C C . ASP B 1 316 ? -39.776 39.406 25.577 1.00 15.39 ? 349 ASP B C 1 ATOM 5838 O O . ASP B 1 316 ? -39.813 38.616 24.556 1.00 11.42 ? 349 ASP B O 1 ATOM 5839 C CB . ASP B 1 316 ? -37.972 40.241 27.004 1.00 16.54 ? 349 ASP B CB 1 ATOM 5840 C CG . ASP B 1 316 ? -38.458 41.275 28.033 1.00 17.07 ? 349 ASP B CG 1 ATOM 5841 O OD1 . ASP B 1 316 ? -39.717 41.516 28.105 1.00 14.66 ? 349 ASP B OD1 1 ATOM 5842 O OD2 . ASP B 1 316 ? -37.565 41.766 28.790 1.00 16.33 -1 349 ASP B OD2 1 ATOM 5843 N N . MET B 1 317 ? -40.386 40.600 25.652 1.00 17.06 ? 350 MET B N 1 ATOM 5844 C CA . MET B 1 317 ? -41.053 41.123 24.447 1.00 19.99 ? 350 MET B CA 1 ATOM 5845 C C . MET B 1 317 ? -40.979 42.574 24.377 1.00 17.71 ? 350 MET B C 1 ATOM 5846 O O . MET B 1 317 ? -41.131 43.198 25.377 1.00 16.30 ? 350 MET B O 1 ATOM 5847 C CB . MET B 1 317 ? -42.484 40.684 24.334 1.00 21.95 ? 350 MET B CB 1 ATOM 5848 C CG . MET B 1 317 ? -43.126 41.074 23.027 1.00 25.32 ? 350 MET B CG 1 ATOM 5849 S SD . MET B 1 317 ? -44.316 42.380 23.385 1.00 30.22 ? 350 MET B SD 1 ATOM 5850 C CE . MET B 1 317 ? -45.522 41.259 24.077 1.00 29.25 ? 350 MET B CE 1 ATOM 5851 N N . LEU B 1 318 ? -40.669 43.036 23.156 1.00 17.86 ? 351 LEU B N 1 ATOM 5852 C CA . LEU B 1 318 ? -40.507 44.430 22.761 1.00 16.92 ? 351 LEU B CA 1 ATOM 5853 C C . LEU B 1 318 ? -41.697 44.821 21.862 1.00 15.91 ? 351 LEU B C 1 ATOM 5854 O O . LEU B 1 318 ? -41.879 44.236 20.817 1.00 15.31 ? 351 LEU B O 1 ATOM 5855 C CB . LEU B 1 318 ? -39.158 44.573 22.050 1.00 17.60 ? 351 LEU B CB 1 ATOM 5856 C CG . LEU B 1 318 ? -38.051 44.678 23.101 1.00 19.42 ? 351 LEU B CG 1 ATOM 5857 C CD1 . LEU B 1 318 ? -37.549 43.303 23.577 1.00 21.64 ? 351 LEU B CD1 1 ATOM 5858 C CD2 . LEU B 1 318 ? -36.866 45.489 22.658 1.00 20.52 ? 351 LEU B CD2 1 ATOM 5859 N N . GLN B 1 319 ? -42.527 45.767 22.309 1.00 15.41 ? 352 GLN B N 1 ATOM 5860 C CA . GLN B 1 319 ? -43.767 46.150 21.646 1.00 14.78 ? 352 GLN B CA 1 ATOM 5861 C C . GLN B 1 319 ? -43.486 47.466 21.047 1.00 15.17 ? 352 GLN B C 1 ATOM 5862 O O . GLN B 1 319 ? -43.112 48.391 21.765 1.00 17.32 ? 352 GLN B O 1 ATOM 5863 C CB . GLN B 1 319 ? -44.918 46.253 22.655 1.00 14.57 ? 352 GLN B CB 1 ATOM 5864 C CG . GLN B 1 319 ? -46.214 46.784 22.076 1.00 14.78 ? 352 GLN B CG 1 ATOM 5865 C CD . GLN B 1 319 ? -46.699 45.905 20.924 1.00 15.99 ? 352 GLN B CD 1 ATOM 5866 O OE1 . GLN B 1 319 ? -47.225 44.830 21.147 1.00 16.45 ? 352 GLN B OE1 1 ATOM 5867 N NE2 . GLN B 1 319 ? -46.498 46.346 19.679 1.00 16.25 ? 352 GLN B NE2 1 ATOM 5868 N N . TYR B 1 320 ? -43.606 47.574 19.735 1.00 16.61 ? 353 TYR B N 1 ATOM 5869 C CA . TYR B 1 320 ? -43.226 48.810 19.005 1.00 18.79 ? 353 TYR B CA 1 ATOM 5870 C C . TYR B 1 320 ? -44.494 49.442 18.459 1.00 18.12 ? 353 TYR B C 1 ATOM 5871 O O . TYR B 1 320 ? -45.425 48.731 18.132 1.00 16.61 ? 353 TYR B O 1 ATOM 5872 C CB . TYR B 1 320 ? -42.215 48.546 17.820 1.00 20.90 ? 353 TYR B CB 1 ATOM 5873 C CG . TYR B 1 320 ? -40.765 48.270 18.203 1.00 22.72 ? 353 TYR B CG 1 ATOM 5874 C CD1 . TYR B 1 320 ? -39.874 49.328 18.535 1.00 25.17 ? 353 TYR B CD1 1 ATOM 5875 C CD2 . TYR B 1 320 ? -40.276 46.943 18.251 1.00 24.29 ? 353 TYR B CD2 1 ATOM 5876 C CE1 . TYR B 1 320 ? -38.543 49.059 18.848 1.00 26.53 ? 353 TYR B CE1 1 ATOM 5877 C CE2 . TYR B 1 320 ? -38.951 46.671 18.563 1.00 25.37 ? 353 TYR B CE2 1 ATOM 5878 C CZ . TYR B 1 320 ? -38.102 47.727 18.857 1.00 26.54 ? 353 TYR B CZ 1 ATOM 5879 O OH . TYR B 1 320 ? -36.832 47.439 19.207 1.00 30.68 ? 353 TYR B OH 1 ATOM 5880 N N . TYR B 1 321 ? -44.523 50.768 18.344 1.00 16.88 ? 354 TYR B N 1 ATOM 5881 C CA . TYR B 1 321 ? -45.663 51.371 17.792 1.00 16.10 ? 354 TYR B CA 1 ATOM 5882 C C . TYR B 1 321 ? -45.334 52.602 17.051 1.00 16.73 ? 354 TYR B C 1 ATOM 5883 O O . TYR B 1 321 ? -44.281 53.168 17.247 1.00 16.37 ? 354 TYR B O 1 ATOM 5884 C CB . TYR B 1 321 ? -46.682 51.675 18.871 1.00 16.58 ? 354 TYR B CB 1 ATOM 5885 C CG . TYR B 1 321 ? -46.493 52.995 19.606 1.00 16.47 ? 354 TYR B CG 1 ATOM 5886 C CD1 . TYR B 1 321 ? -45.491 53.144 20.505 1.00 17.91 ? 354 TYR B CD1 1 ATOM 5887 C CD2 . TYR B 1 321 ? -47.324 54.079 19.389 1.00 15.81 ? 354 TYR B CD2 1 ATOM 5888 C CE1 . TYR B 1 321 ? -45.344 54.308 21.187 1.00 17.28 ? 354 TYR B CE1 1 ATOM 5889 C CE2 . TYR B 1 321 ? -47.157 55.235 20.039 1.00 14.96 ? 354 TYR B CE2 1 ATOM 5890 C CZ . TYR B 1 321 ? -46.165 55.309 20.945 1.00 16.39 ? 354 TYR B CZ 1 ATOM 5891 O OH . TYR B 1 321 ? -45.943 56.407 21.662 1.00 18.43 ? 354 TYR B OH 1 ATOM 5892 N N . LEU B 1 322 ? -46.278 52.969 16.176 1.00 19.33 ? 355 LEU B N 1 ATOM 5893 C CA . LEU B 1 322 ? -46.370 54.266 15.513 1.00 21.39 ? 355 LEU B CA 1 ATOM 5894 C C . LEU B 1 322 ? -47.503 55.088 16.111 1.00 21.77 ? 355 LEU B C 1 ATOM 5895 O O . LEU B 1 322 ? -48.644 54.627 16.140 1.00 23.34 ? 355 LEU B O 1 ATOM 5896 C CB . LEU B 1 322 ? -46.622 54.123 14.013 1.00 22.42 ? 355 LEU B CB 1 ATOM 5897 C CG . LEU B 1 322 ? -46.579 55.373 13.109 1.00 23.41 ? 355 LEU B CG 1 ATOM 5898 C CD1 . LEU B 1 322 ? -45.330 56.222 13.322 1.00 23.94 ? 355 LEU B CD1 1 ATOM 5899 C CD2 . LEU B 1 322 ? -46.629 54.897 11.650 1.00 25.64 ? 355 LEU B CD2 1 ATOM 5900 N N . ASN B 1 323 ? -47.172 56.302 16.486 1.00 22.40 ? 356 ASN B N 1 ATOM 5901 C CA . ASN B 1 323 ? -48.102 57.295 16.924 1.00 22.00 ? 356 ASN B CA 1 ATOM 5902 C C . ASN B 1 323 ? -48.534 57.835 15.585 1.00 19.89 ? 356 ASN B C 1 ATOM 5903 O O . ASN B 1 323 ? -47.881 58.594 14.941 1.00 18.53 ? 356 ASN B O 1 ATOM 5904 C CB . ASN B 1 323 ? -47.429 58.347 17.815 1.00 22.07 ? 356 ASN B CB 1 ATOM 5905 C CG . ASN B 1 323 ? -48.378 59.342 18.382 1.00 24.75 ? 356 ASN B CG 1 ATOM 5906 O OD1 . ASN B 1 323 ? -49.499 59.407 18.006 1.00 27.16 ? 356 ASN B OD1 1 ATOM 5907 N ND2 . ASN B 1 323 ? -47.910 60.130 19.289 1.00 28.31 ? 356 ASN B ND2 1 ATOM 5908 N N . LEU B 1 324 ? -49.640 57.307 15.169 1.00 18.33 ? 357 LEU B N 1 ATOM 5909 C CA . LEU B 1 324 ? -50.360 57.654 13.996 1.00 18.36 ? 357 LEU B CA 1 ATOM 5910 C C . LEU B 1 324 ? -50.640 59.150 13.832 1.00 18.16 ? 357 LEU B C 1 ATOM 5911 O O . LEU B 1 324 ? -50.557 59.718 12.724 1.00 18.98 ? 357 LEU B O 1 ATOM 5912 C CB . LEU B 1 324 ? -51.648 56.869 14.115 1.00 17.76 ? 357 LEU B CB 1 ATOM 5913 C CG . LEU B 1 324 ? -52.641 57.193 13.059 1.00 19.56 ? 357 LEU B CG 1 ATOM 5914 C CD1 . LEU B 1 324 ? -52.049 56.824 11.708 1.00 22.01 ? 357 LEU B CD1 1 ATOM 5915 C CD2 . LEU B 1 324 ? -53.854 56.371 13.366 1.00 21.71 ? 357 LEU B CD2 1 ATOM 5916 N N . THR B 1 325 ? -51.011 59.760 14.950 1.00 19.11 ? 358 THR B N 1 ATOM 5917 C CA . THR B 1 325 ? -51.433 61.124 15.000 1.00 21.81 ? 358 THR B CA 1 ATOM 5918 C C . THR B 1 325 ? -50.183 61.922 14.738 1.00 26.96 ? 358 THR B C 1 ATOM 5919 O O . THR B 1 325 ? -50.067 62.524 13.656 1.00 26.80 ? 358 THR B O 1 ATOM 5920 C CB . THR B 1 325 ? -52.017 61.494 16.365 1.00 21.16 ? 358 THR B CB 1 ATOM 5921 O OG1 . THR B 1 325 ? -53.152 60.701 16.598 1.00 20.64 ? 358 THR B OG1 1 ATOM 5922 C CG2 . THR B 1 325 ? -52.491 62.937 16.399 1.00 21.66 ? 358 THR B CG2 1 ATOM 5923 N N . GLU B 1 326 ? -49.235 61.868 15.703 1.00 31.62 ? 359 GLU B N 1 ATOM 5924 C CA . GLU B 1 326 ? -47.887 62.482 15.550 1.00 31.94 ? 359 GLU B CA 1 ATOM 5925 C C . GLU B 1 326 ? -47.320 62.317 14.098 1.00 29.67 ? 359 GLU B C 1 ATOM 5926 O O . GLU B 1 326 ? -46.731 63.254 13.543 1.00 28.90 ? 359 GLU B O 1 ATOM 5927 C CB . GLU B 1 326 ? -46.881 61.965 16.594 1.00 29.46 ? 359 GLU B CB 1 ATOM 5928 C CG . GLU B 1 326 ? -45.511 62.656 16.525 1.00 33.59 ? 359 GLU B CG 1 ATOM 5929 C CD . GLU B 1 326 ? -44.318 61.703 16.754 1.00 40.24 ? 359 GLU B CD 1 ATOM 5930 O OE1 . GLU B 1 326 ? -44.343 60.829 17.661 1.00 39.93 ? 359 GLU B OE1 1 ATOM 5931 O OE2 . GLU B 1 326 ? -43.336 61.789 15.986 1.00 47.91 -1 359 GLU B OE2 1 ATOM 5932 N N . ALA B 1 327 ? -47.526 61.144 13.509 1.00 27.04 ? 360 ALA B N 1 ATOM 5933 C CA . ALA B 1 327 ? -46.925 60.790 12.239 1.00 27.23 ? 360 ALA B CA 1 ATOM 5934 C C . ALA B 1 327 ? -47.651 61.401 11.098 1.00 27.59 ? 360 ALA B C 1 ATOM 5935 O O . ALA B 1 327 ? -46.992 61.923 10.170 1.00 28.46 ? 360 ALA B O 1 ATOM 5936 C CB . ALA B 1 327 ? -46.896 59.291 12.043 1.00 29.83 ? 360 ALA B CB 1 ATOM 5937 N N . ASN B 1 328 ? -48.980 61.361 11.109 1.00 24.33 ? 361 ASN B N 1 ATOM 5938 C CA . ASN B 1 328 ? -49.633 62.199 10.100 1.00 26.28 ? 361 ASN B CA 1 ATOM 5939 C C . ASN B 1 328 ? -49.427 63.751 10.213 1.00 27.91 ? 361 ASN B C 1 ATOM 5940 O O . ASN B 1 328 ? -49.364 64.431 9.188 1.00 29.14 ? 361 ASN B O 1 ATOM 5941 C CB . ASN B 1 328 ? -51.093 61.861 9.968 1.00 25.43 ? 361 ASN B CB 1 ATOM 5942 C CG . ASN B 1 328 ? -51.318 60.499 9.355 1.00 23.65 ? 361 ASN B CG 1 ATOM 5943 O OD1 . ASN B 1 328 ? -50.565 60.026 8.485 1.00 22.48 ? 361 ASN B OD1 1 ATOM 5944 N ND2 . ASN B 1 328 ? -52.378 59.862 9.795 1.00 22.92 ? 361 ASN B ND2 1 ATOM 5945 N N . LEU B 1 329 ? -49.318 64.300 11.425 1.00 27.51 ? 362 LEU B N 1 ATOM 5946 C CA . LEU B 1 329 ? -49.051 65.720 11.590 1.00 28.32 ? 362 LEU B CA 1 ATOM 5947 C C . LEU B 1 329 ? -47.710 66.092 10.975 1.00 30.86 ? 362 LEU B C 1 ATOM 5948 O O . LEU B 1 329 ? -47.618 67.134 10.332 1.00 30.78 ? 362 LEU B O 1 ATOM 5949 C CB . LEU B 1 329 ? -49.111 66.135 13.064 1.00 28.49 ? 362 LEU B CB 1 ATOM 5950 C CG . LEU B 1 329 ? -50.576 66.299 13.502 1.00 32.01 ? 362 LEU B CG 1 ATOM 5951 C CD1 . LEU B 1 329 ? -50.750 66.310 15.017 1.00 33.95 ? 362 LEU B CD1 1 ATOM 5952 C CD2 . LEU B 1 329 ? -51.196 67.555 12.922 1.00 33.43 ? 362 LEU B CD2 1 ATOM 5953 N N . LYS B 1 330 ? -46.700 65.225 11.135 1.00 33.76 ? 363 LYS B N 1 ATOM 5954 C CA . LYS B 1 330 ? -45.310 65.505 10.704 1.00 35.93 ? 363 LYS B CA 1 ATOM 5955 C C . LYS B 1 330 ? -44.980 64.968 9.310 1.00 34.90 ? 363 LYS B C 1 ATOM 5956 O O . LYS B 1 330 ? -44.010 65.396 8.666 1.00 37.00 ? 363 LYS B O 1 ATOM 5957 C CB . LYS B 1 330 ? -44.303 64.893 11.695 1.00 38.52 ? 363 LYS B CB 1 ATOM 5958 C CG . LYS B 1 330 ? -44.283 65.537 13.081 1.00 42.59 ? 363 LYS B CG 1 ATOM 5959 C CD . LYS B 1 330 ? -43.226 64.901 13.976 1.00 45.50 ? 363 LYS B CD 1 ATOM 5960 C CE . LYS B 1 330 ? -41.821 65.366 13.563 1.00 51.28 ? 363 LYS B CE 1 ATOM 5961 N NZ . LYS B 1 330 ? -40.819 64.297 13.201 1.00 52.07 1 363 LYS B NZ 1 ATOM 5962 N N . GLY B 1 331 ? -45.769 64.012 8.852 1.00 33.28 ? 364 GLY B N 1 ATOM 5963 C CA . GLY B 1 331 ? -45.399 63.262 7.666 1.00 33.70 ? 364 GLY B CA 1 ATOM 5964 C C . GLY B 1 331 ? -44.134 62.444 7.799 1.00 33.10 ? 364 GLY B C 1 ATOM 5965 O O . GLY B 1 331 ? -43.434 62.242 6.827 1.00 33.58 ? 364 GLY B O 1 ATOM 5966 N N . GLU B 1 332 ? -43.869 61.919 8.988 1.00 35.88 ? 365 GLU B N 1 ATOM 5967 C CA . GLU B 1 332 ? -42.692 61.078 9.219 1.00 35.98 ? 365 GLU B CA 1 ATOM 5968 C C . GLU B 1 332 ? -43.075 59.756 9.873 1.00 31.43 ? 365 GLU B C 1 ATOM 5969 O O . GLU B 1 332 ? -43.950 59.728 10.695 1.00 28.37 ? 365 GLU B O 1 ATOM 5970 C CB . GLU B 1 332 ? -41.680 61.821 10.096 1.00 38.97 ? 365 GLU B CB 1 ATOM 5971 C CG . GLU B 1 332 ? -41.271 63.197 9.570 1.00 41.73 ? 365 GLU B CG 1 ATOM 5972 C CD . GLU B 1 332 ? -40.487 63.175 8.239 1.00 46.37 ? 365 GLU B CD 1 ATOM 5973 O OE1 . GLU B 1 332 ? -39.882 62.153 7.833 1.00 45.27 ? 365 GLU B OE1 1 ATOM 5974 O OE2 . GLU B 1 332 ? -40.444 64.231 7.574 1.00 55.38 -1 365 GLU B OE2 1 ATOM 5975 N N . SER B 1 333 ? -42.401 58.680 9.482 1.00 33.12 ? 366 SER B N 1 ATOM 5976 C CA . SER B 1 333 ? -42.592 57.307 10.014 1.00 34.96 ? 366 SER B CA 1 ATOM 5977 C C . SER B 1 333 ? -41.865 57.066 11.323 1.00 35.23 ? 366 SER B C 1 ATOM 5978 O O . SER B 1 333 ? -40.994 56.207 11.387 1.00 39.01 ? 366 SER B O 1 ATOM 5979 C CB . SER B 1 333 ? -42.034 56.268 9.026 1.00 37.08 ? 366 SER B CB 1 ATOM 5980 O OG . SER B 1 333 ? -42.826 56.193 7.860 1.00 43.59 ? 366 SER B OG 1 ATOM 5981 N N . ILE B 1 334 ? -42.240 57.788 12.369 1.00 37.26 ? 367 ILE B N 1 ATOM 5982 C CA . ILE B 1 334 ? -41.607 57.659 13.692 1.00 37.14 ? 367 ILE B CA 1 ATOM 5983 C C . ILE B 1 334 ? -42.121 56.443 14.532 1.00 30.52 ? 367 ILE B C 1 ATOM 5984 O O . ILE B 1 334 ? -42.915 56.574 15.472 1.00 27.66 ? 367 ILE B O 1 ATOM 5985 C CB . ILE B 1 334 ? -41.751 58.971 14.506 1.00 42.55 ? 367 ILE B CB 1 ATOM 5986 C CG1 . ILE B 1 334 ? -41.454 60.212 13.644 1.00 45.74 ? 367 ILE B CG1 1 ATOM 5987 C CG2 . ILE B 1 334 ? -40.821 58.937 15.705 1.00 46.57 ? 367 ILE B CG2 1 ATOM 5988 C CD1 . ILE B 1 334 ? -40.177 60.126 12.843 1.00 49.44 ? 367 ILE B CD1 1 ATOM 5989 N N . TRP B 1 335 ? -41.626 55.265 14.193 1.00 27.44 ? 368 TRP B N 1 ATOM 5990 C CA . TRP B 1 335 ? -41.906 54.059 14.973 1.00 26.17 ? 368 TRP B CA 1 ATOM 5991 C C . TRP B 1 335 ? -41.082 54.048 16.255 1.00 23.62 ? 368 TRP B C 1 ATOM 5992 O O . TRP B 1 335 ? -39.884 54.272 16.219 1.00 22.68 ? 368 TRP B O 1 ATOM 5993 C CB . TRP B 1 335 ? -41.609 52.790 14.184 1.00 26.78 ? 368 TRP B CB 1 ATOM 5994 C CG . TRP B 1 335 ? -42.674 52.399 13.193 1.00 26.85 ? 368 TRP B CG 1 ATOM 5995 C CD1 . TRP B 1 335 ? -42.736 52.744 11.859 1.00 27.40 ? 368 TRP B CD1 1 ATOM 5996 C CD2 . TRP B 1 335 ? -43.777 51.542 13.436 1.00 24.33 ? 368 TRP B CD2 1 ATOM 5997 N NE1 . TRP B 1 335 ? -43.831 52.141 11.267 1.00 26.63 ? 368 TRP B NE1 1 ATOM 5998 C CE2 . TRP B 1 335 ? -44.483 51.395 12.204 1.00 24.64 ? 368 TRP B CE2 1 ATOM 5999 C CE3 . TRP B 1 335 ? -44.233 50.867 14.558 1.00 23.44 ? 368 TRP B CE3 1 ATOM 6000 C CZ2 . TRP B 1 335 ? -45.645 50.640 12.081 1.00 24.67 ? 368 TRP B CZ2 1 ATOM 6001 C CZ3 . TRP B 1 335 ? -45.401 50.119 14.433 1.00 24.69 ? 368 TRP B CZ3 1 ATOM 6002 C CH2 . TRP B 1 335 ? -46.101 50.020 13.193 1.00 25.02 ? 368 TRP B CH2 1 ATOM 6003 N N . LYS B 1 336 ? -41.758 53.792 17.378 1.00 21.95 ? 369 LYS B N 1 ATOM 6004 C CA . LYS B 1 336 ? -41.168 53.843 18.682 1.00 21.95 ? 369 LYS B CA 1 ATOM 6005 C C . LYS B 1 336 ? -41.550 52.668 19.517 1.00 21.80 ? 369 LYS B C 1 ATOM 6006 O O . LYS B 1 336 ? -42.638 52.062 19.351 1.00 19.99 ? 369 LYS B O 1 ATOM 6007 C CB . LYS B 1 336 ? -41.646 55.048 19.490 1.00 22.66 ? 369 LYS B CB 1 ATOM 6008 C CG . LYS B 1 336 ? -41.751 56.344 18.712 1.00 23.53 ? 369 LYS B CG 1 ATOM 6009 C CD . LYS B 1 336 ? -42.250 57.358 19.704 1.00 24.07 ? 369 LYS B CD 1 ATOM 6010 C CE . LYS B 1 336 ? -42.752 58.535 18.952 1.00 25.82 ? 369 LYS B CE 1 ATOM 6011 N NZ . LYS B 1 336 ? -42.731 59.672 19.887 1.00 28.02 1 369 LYS B NZ 1 ATOM 6012 N N . LEU B 1 337 ? -40.660 52.455 20.484 1.00 21.07 ? 370 LEU B N 1 ATOM 6013 C CA . LEU B 1 337 ? -40.827 51.517 21.550 1.00 23.05 ? 370 LEU B CA 1 ATOM 6014 C C . LEU B 1 337 ? -41.901 52.061 22.493 1.00 21.83 ? 370 LEU B C 1 ATOM 6015 O O . LEU B 1 337 ? -41.776 53.201 22.988 1.00 22.53 ? 370 LEU B O 1 ATOM 6016 C CB . LEU B 1 337 ? -39.465 51.281 22.270 1.00 24.29 ? 370 LEU B CB 1 ATOM 6017 C CG . LEU B 1 337 ? -39.389 50.154 23.330 1.00 24.14 ? 370 LEU B CG 1 ATOM 6018 C CD1 . LEU B 1 337 ? -39.379 48.807 22.599 1.00 23.90 ? 370 LEU B CD1 1 ATOM 6019 C CD2 . LEU B 1 337 ? -38.202 50.294 24.264 1.00 23.15 ? 370 LEU B CD2 1 ATOM 6020 N N . GLU B 1 338 ? -42.980 51.269 22.692 1.00 22.12 ? 371 GLU B N 1 ATOM 6021 C CA . GLU B 1 338 ? -44.035 51.552 23.755 1.00 21.03 ? 371 GLU B CA 1 ATOM 6022 C C . GLU B 1 338 ? -43.526 51.007 25.088 1.00 18.81 ? 371 GLU B C 1 ATOM 6023 O O . GLU B 1 338 ? -43.383 51.768 26.083 1.00 14.84 ? 371 GLU B O 1 ATOM 6024 C CB . GLU B 1 338 ? -45.341 50.860 23.413 1.00 20.89 ? 371 GLU B CB 1 ATOM 6025 C CG . GLU B 1 338 ? -46.588 51.345 24.112 1.00 20.10 ? 371 GLU B CG 1 ATOM 6026 C CD . GLU B 1 338 ? -47.857 50.555 23.628 1.00 18.82 ? 371 GLU B CD 1 ATOM 6027 O OE1 . GLU B 1 338 ? -47.872 49.331 23.397 1.00 18.05 ? 371 GLU B OE1 1 ATOM 6028 O OE2 . GLU B 1 338 ? -48.878 51.155 23.449 1.00 18.02 -1 371 GLU B OE2 1 ATOM 6029 N N . TYR B 1 339 ? -43.091 49.754 25.051 1.00 18.65 ? 372 TYR B N 1 ATOM 6030 C CA . TYR B 1 339 ? -42.449 49.095 26.170 1.00 20.10 ? 372 TYR B CA 1 ATOM 6031 C C . TYR B 1 339 ? -41.614 47.856 25.878 1.00 20.17 ? 372 TYR B C 1 ATOM 6032 O O . TYR B 1 339 ? -41.609 47.341 24.827 1.00 19.73 ? 372 TYR B O 1 ATOM 6033 C CB . TYR B 1 339 ? -43.479 48.679 27.229 1.00 18.98 ? 372 TYR B CB 1 ATOM 6034 C CG . TYR B 1 339 ? -44.431 47.665 26.752 1.00 21.79 ? 372 TYR B CG 1 ATOM 6035 C CD1 . TYR B 1 339 ? -44.137 46.357 26.821 1.00 23.79 ? 372 TYR B CD1 1 ATOM 6036 C CD2 . TYR B 1 339 ? -45.619 48.012 26.177 1.00 22.33 ? 372 TYR B CD2 1 ATOM 6037 C CE1 . TYR B 1 339 ? -44.999 45.412 26.345 1.00 25.08 ? 372 TYR B CE1 1 ATOM 6038 C CE2 . TYR B 1 339 ? -46.499 47.071 25.765 1.00 20.64 ? 372 TYR B CE2 1 ATOM 6039 C CZ . TYR B 1 339 ? -46.185 45.774 25.850 1.00 20.94 ? 372 TYR B CZ 1 ATOM 6040 O OH . TYR B 1 339 ? -47.036 44.823 25.395 1.00 19.07 ? 372 TYR B OH 1 ATOM 6041 N N . ILE B 1 340 ? -40.889 47.439 26.895 1.00 19.47 ? 373 ILE B N 1 ATOM 6042 C CA . ILE B 1 340 ? -40.287 46.139 27.099 1.00 17.84 ? 373 ILE B CA 1 ATOM 6043 C C . ILE B 1 340 ? -41.016 45.386 28.246 1.00 16.62 ? 373 ILE B C 1 ATOM 6044 O O . ILE B 1 340 ? -41.018 45.826 29.352 1.00 17.40 ? 373 ILE B O 1 ATOM 6045 C CB . ILE B 1 340 ? -38.833 46.387 27.480 1.00 18.98 ? 373 ILE B CB 1 ATOM 6046 C CG1 . ILE B 1 340 ? -38.153 47.119 26.290 1.00 18.33 ? 373 ILE B CG1 1 ATOM 6047 C CG2 . ILE B 1 340 ? -38.181 45.099 28.032 1.00 18.48 ? 373 ILE B CG2 1 ATOM 6048 C CD1 . ILE B 1 340 ? -36.841 47.737 26.644 1.00 18.41 ? 373 ILE B CD1 1 ATOM 6049 N N . LEU B 1 341 ? -41.658 44.268 27.974 1.00 15.36 ? 374 LEU B N 1 ATOM 6050 C CA . LEU B 1 341 ? -42.501 43.678 28.986 1.00 16.46 ? 374 LEU B CA 1 ATOM 6051 C C . LEU B 1 341 ? -41.826 43.489 30.380 1.00 17.07 ? 374 LEU B C 1 ATOM 6052 O O . LEU B 1 341 ? -42.385 43.929 31.411 1.00 17.39 ? 374 LEU B O 1 ATOM 6053 C CB . LEU B 1 341 ? -43.082 42.337 28.531 1.00 15.76 ? 374 LEU B CB 1 ATOM 6054 C CG . LEU B 1 341 ? -44.436 42.055 29.101 1.00 14.97 ? 374 LEU B CG 1 ATOM 6055 C CD1 . LEU B 1 341 ? -45.098 41.055 28.174 1.00 16.58 ? 374 LEU B CD1 1 ATOM 6056 C CD2 . LEU B 1 341 ? -44.330 41.479 30.451 1.00 14.96 ? 374 LEU B CD2 1 ATOM 6057 N N . THR B 1 342 ? -40.694 42.827 30.460 1.00 15.67 ? 375 THR B N 1 ATOM 6058 C CA . THR B 1 342 ? -40.226 42.574 31.782 1.00 16.66 ? 375 THR B CA 1 ATOM 6059 C C . THR B 1 342 ? -39.867 43.860 32.488 1.00 19.27 ? 375 THR B C 1 ATOM 6060 O O . THR B 1 342 ? -40.053 43.929 33.680 1.00 23.82 ? 375 THR B O 1 ATOM 6061 C CB . THR B 1 342 ? -39.047 41.577 31.887 1.00 16.30 ? 375 THR B CB 1 ATOM 6062 O OG1 . THR B 1 342 ? -37.903 42.039 31.142 1.00 13.94 ? 375 THR B OG1 1 ATOM 6063 C CG2 . THR B 1 342 ? -39.526 40.090 31.518 1.00 15.72 ? 375 THR B CG2 1 ATOM 6064 N N . GLN B 1 343 ? -39.405 44.898 31.798 1.00 20.92 ? 376 GLN B N 1 ATOM 6065 C CA . GLN B 1 343 ? -39.145 46.197 32.481 1.00 22.48 ? 376 GLN B CA 1 ATOM 6066 C C . GLN B 1 343 ? -40.357 46.966 33.014 1.00 19.48 ? 376 GLN B C 1 ATOM 6067 O O . GLN B 1 343 ? -40.327 47.430 34.128 1.00 18.32 ? 376 GLN B O 1 ATOM 6068 C CB . GLN B 1 343 ? -38.453 47.189 31.538 1.00 27.06 ? 376 GLN B CB 1 ATOM 6069 C CG . GLN B 1 343 ? -36.993 46.905 31.262 1.00 34.34 ? 376 GLN B CG 1 ATOM 6070 C CD . GLN B 1 343 ? -36.061 47.126 32.489 1.00 38.63 ? 376 GLN B CD 1 ATOM 6071 O OE1 . GLN B 1 343 ? -36.181 48.119 33.268 1.00 37.05 ? 376 GLN B OE1 1 ATOM 6072 N NE2 . GLN B 1 343 ? -35.118 46.189 32.655 1.00 39.88 ? 376 GLN B NE2 1 ATOM 6073 N N . THR B 1 344 ? -41.373 47.160 32.191 1.00 16.18 ? 377 THR B N 1 ATOM 6074 C CA . THR B 1 344 ? -42.357 48.110 32.535 1.00 18.07 ? 377 THR B CA 1 ATOM 6075 C C . THR B 1 344 ? -43.305 47.539 33.623 1.00 18.93 ? 377 THR B C 1 ATOM 6076 O O . THR B 1 344 ? -43.844 48.266 34.423 1.00 16.65 ? 377 THR B O 1 ATOM 6077 C CB . THR B 1 344 ? -43.115 48.580 31.276 1.00 18.90 ? 377 THR B CB 1 ATOM 6078 O OG1 . THR B 1 344 ? -43.820 49.802 31.553 1.00 20.45 ? 377 THR B OG1 1 ATOM 6079 C CG2 . THR B 1 344 ? -44.094 47.543 30.774 1.00 19.57 ? 377 THR B CG2 1 ATOM 6080 N N . TYR B 1 345 ? -43.479 46.224 33.600 1.00 19.24 ? 378 TYR B N 1 ATOM 6081 C CA . TYR B 1 345 ? -44.074 45.455 34.655 1.00 21.01 ? 378 TYR B CA 1 ATOM 6082 C C . TYR B 1 345 ? -43.011 44.787 35.621 1.00 24.40 ? 378 TYR B C 1 ATOM 6083 O O . TYR B 1 345 ? -43.355 44.023 36.549 1.00 23.28 ? 378 TYR B O 1 ATOM 6084 C CB . TYR B 1 345 ? -44.909 44.369 34.012 1.00 20.34 ? 378 TYR B CB 1 ATOM 6085 C CG . TYR B 1 345 ? -46.072 44.804 33.088 1.00 19.23 ? 378 TYR B CG 1 ATOM 6086 C CD1 . TYR B 1 345 ? -47.055 45.637 33.508 1.00 18.70 ? 378 TYR B CD1 1 ATOM 6087 C CD2 . TYR B 1 345 ? -46.225 44.242 31.874 1.00 17.42 ? 378 TYR B CD2 1 ATOM 6088 C CE1 . TYR B 1 345 ? -48.110 45.975 32.681 1.00 18.21 ? 378 TYR B CE1 1 ATOM 6089 C CE2 . TYR B 1 345 ? -47.253 44.559 31.074 1.00 17.71 ? 378 TYR B CE2 1 ATOM 6090 C CZ . TYR B 1 345 ? -48.216 45.434 31.457 1.00 16.99 ? 378 TYR B CZ 1 ATOM 6091 O OH . TYR B 1 345 ? -49.289 45.681 30.593 1.00 14.58 ? 378 TYR B OH 1 ATOM 6092 N N . ASP B 1 346 ? -41.747 45.152 35.460 1.00 25.65 ? 379 ASP B N 1 ATOM 6093 C CA A ASP B 1 346 ? -40.672 44.621 36.281 0.50 29.90 ? 379 ASP B CA 1 ATOM 6094 C CA B ASP B 1 346 ? -40.694 44.634 36.326 0.50 29.90 ? 379 ASP B CA 1 ATOM 6095 C C . ASP B 1 346 ? -41.054 43.247 36.915 1.00 30.15 ? 379 ASP B C 1 ATOM 6096 O O . ASP B 1 346 ? -41.387 43.099 38.060 1.00 28.00 ? 379 ASP B O 1 ATOM 6097 C CB A ASP B 1 346 ? -40.011 45.762 37.146 0.50 32.09 ? 379 ASP B CB 1 ATOM 6098 C CB B ASP B 1 346 ? -40.109 45.652 37.388 0.50 32.12 ? 379 ASP B CB 1 ATOM 6099 C CG A ASP B 1 346 ? -39.920 45.477 38.656 0.50 32.12 ? 379 ASP B CG 1 ATOM 6100 C CG B ASP B 1 346 ? -41.047 46.832 37.762 0.50 30.93 ? 379 ASP B CG 1 ATOM 6101 O OD1 A ASP B 1 346 ? -40.529 46.295 39.396 0.50 35.45 ? 379 ASP B OD1 1 ATOM 6102 O OD1 B ASP B 1 346 ? -41.436 47.609 36.875 0.50 33.94 ? 379 ASP B OD1 1 ATOM 6103 O OD2 A ASP B 1 346 ? -39.212 44.530 39.092 0.50 26.38 -1 379 ASP B OD2 1 ATOM 6104 O OD2 B ASP B 1 346 ? -41.305 47.060 38.967 0.50 28.82 -1 379 ASP B OD2 1 ATOM 6105 N N . ILE B 1 347 ? -41.010 42.252 36.033 1.00 34.47 ? 380 ILE B N 1 ATOM 6106 C CA . ILE B 1 347 ? -41.100 40.793 36.305 1.00 33.84 ? 380 ILE B CA 1 ATOM 6107 C C . ILE B 1 347 ? -39.892 40.137 35.549 1.00 31.01 ? 380 ILE B C 1 ATOM 6108 O O . ILE B 1 347 ? -39.140 40.824 34.786 1.00 24.67 ? 380 ILE B O 1 ATOM 6109 C CB . ILE B 1 347 ? -42.445 40.164 35.843 1.00 35.04 ? 380 ILE B CB 1 ATOM 6110 C CG1 . ILE B 1 347 ? -42.635 40.362 34.320 1.00 39.10 ? 380 ILE B CG1 1 ATOM 6111 C CG2 . ILE B 1 347 ? -43.621 40.786 36.598 1.00 32.45 ? 380 ILE B CG2 1 ATOM 6112 C CD1 . ILE B 1 347 ? -43.572 39.369 33.660 1.00 39.65 ? 380 ILE B CD1 1 ATOM 6113 N N . GLU B 1 348 ? -39.673 38.846 35.821 1.00 30.52 ? 381 GLU B N 1 ATOM 6114 C CA . GLU B 1 348 ? -38.365 38.225 35.540 1.00 30.96 ? 381 GLU B CA 1 ATOM 6115 C C . GLU B 1 348 ? -38.322 37.808 34.149 1.00 25.38 ? 381 GLU B C 1 ATOM 6116 O O . GLU B 1 348 ? -37.355 37.935 33.537 1.00 26.49 ? 381 GLU B O 1 ATOM 6117 C CB . GLU B 1 348 ? -38.052 37.016 36.440 1.00 38.49 ? 381 GLU B CB 1 ATOM 6118 C CG . GLU B 1 348 ? -38.122 37.232 37.976 1.00 47.43 ? 381 GLU B CG 1 ATOM 6119 C CD . GLU B 1 348 ? -36.912 37.996 38.599 1.00 55.26 ? 381 GLU B CD 1 ATOM 6120 O OE1 . GLU B 1 348 ? -35.928 38.326 37.872 1.00 51.14 ? 381 GLU B OE1 1 ATOM 6121 O OE2 . GLU B 1 348 ? -36.945 38.266 39.843 1.00 58.18 -1 381 GLU B OE2 1 ATOM 6122 N N . ASP B 1 349 ? -39.407 37.294 33.640 1.00 26.86 ? 382 ASP B N 1 ATOM 6123 C CA . ASP B 1 349 ? -39.451 36.715 32.296 1.00 28.16 ? 382 ASP B CA 1 ATOM 6124 C C . ASP B 1 349 ? -40.912 36.444 31.902 1.00 26.11 ? 382 ASP B C 1 ATOM 6125 O O . ASP B 1 349 ? -41.844 36.809 32.644 1.00 25.43 ? 382 ASP B O 1 ATOM 6126 C CB . ASP B 1 349 ? -38.619 35.401 32.234 1.00 28.31 ? 382 ASP B CB 1 ATOM 6127 C CG . ASP B 1 349 ? -39.186 34.296 33.124 1.00 29.54 ? 382 ASP B CG 1 ATOM 6128 O OD1 . ASP B 1 349 ? -40.374 34.337 33.551 1.00 29.82 ? 382 ASP B OD1 1 ATOM 6129 O OD2 . ASP B 1 349 ? -38.438 33.330 33.358 1.00 31.78 -1 382 ASP B OD2 1 ATOM 6130 N N . LEU B 1 350 ? -41.102 35.763 30.769 1.00 24.41 ? 383 LEU B N 1 ATOM 6131 C CA . LEU B 1 350 ? -42.424 35.550 30.224 1.00 23.31 ? 383 LEU B CA 1 ATOM 6132 C C . LEU B 1 350 ? -42.964 34.141 30.490 1.00 24.10 ? 383 LEU B C 1 ATOM 6133 O O . LEU B 1 350 ? -43.959 33.761 29.840 1.00 24.18 ? 383 LEU B O 1 ATOM 6134 C CB . LEU B 1 350 ? -42.454 35.892 28.731 1.00 22.12 ? 383 LEU B CB 1 ATOM 6135 C CG . LEU B 1 350 ? -42.593 37.364 28.378 1.00 20.71 ? 383 LEU B CG 1 ATOM 6136 C CD1 . LEU B 1 350 ? -41.425 38.129 28.902 1.00 21.67 ? 383 LEU B CD1 1 ATOM 6137 C CD2 . LEU B 1 350 ? -42.635 37.513 26.889 1.00 19.84 ? 383 LEU B CD2 1 ATOM 6138 N N . GLN B 1 351 ? -42.384 33.415 31.462 1.00 23.50 ? 384 GLN B N 1 ATOM 6139 C CA . GLN B 1 351 ? -42.917 32.112 31.803 1.00 25.88 ? 384 GLN B CA 1 ATOM 6140 C C . GLN B 1 351 ? -44.305 32.259 32.440 1.00 24.32 ? 384 GLN B C 1 ATOM 6141 O O . GLN B 1 351 ? -44.680 33.323 32.952 1.00 22.88 ? 384 GLN B O 1 ATOM 6142 C CB . GLN B 1 351 ? -42.006 31.236 32.724 1.00 31.41 ? 384 GLN B CB 1 ATOM 6143 C CG . GLN B 1 351 ? -40.525 31.546 32.691 1.00 37.60 ? 384 GLN B CG 1 ATOM 6144 C CD . GLN B 1 351 ? -39.586 30.343 32.580 1.00 43.82 ? 384 GLN B CD 1 ATOM 6145 O OE1 . GLN B 1 351 ? -39.840 29.411 31.805 1.00 42.06 ? 384 GLN B OE1 1 ATOM 6146 N NE2 . GLN B 1 351 ? -38.435 30.409 33.299 1.00 41.67 ? 384 GLN B NE2 1 ATOM 6147 N N . PRO B 1 352 ? -45.088 31.176 32.398 1.00 24.74 ? 385 PRO B N 1 ATOM 6148 C CA . PRO B 1 352 ? -46.443 31.221 32.963 1.00 24.79 ? 385 PRO B CA 1 ATOM 6149 C C . PRO B 1 352 ? -46.562 31.673 34.465 1.00 24.61 ? 385 PRO B C 1 ATOM 6150 O O . PRO B 1 352 ? -47.502 32.293 34.858 1.00 20.74 ? 385 PRO B O 1 ATOM 6151 C CB . PRO B 1 352 ? -46.934 29.766 32.778 1.00 25.05 ? 385 PRO B CB 1 ATOM 6152 C CG . PRO B 1 352 ? -46.116 29.208 31.630 1.00 24.67 ? 385 PRO B CG 1 ATOM 6153 C CD . PRO B 1 352 ? -44.804 29.912 31.657 1.00 24.17 ? 385 PRO B CD 1 ATOM 6154 N N . GLU B 1 353 ? -45.617 31.320 35.295 1.00 27.04 ? 386 GLU B N 1 ATOM 6155 C CA . GLU B 1 353 ? -45.723 31.653 36.697 1.00 28.95 ? 386 GLU B CA 1 ATOM 6156 C C . GLU B 1 353 ? -45.485 33.144 36.774 1.00 23.91 ? 386 GLU B C 1 ATOM 6157 O O . GLU B 1 353 ? -46.206 33.815 37.456 1.00 22.80 ? 386 GLU B O 1 ATOM 6158 C CB . GLU B 1 353 ? -44.741 30.841 37.617 1.00 34.87 ? 386 GLU B CB 1 ATOM 6159 C CG . GLU B 1 353 ? -44.466 29.373 37.209 1.00 42.17 ? 386 GLU B CG 1 ATOM 6160 C CD . GLU B 1 353 ? -43.589 29.198 35.923 1.00 47.20 ? 386 GLU B CD 1 ATOM 6161 O OE1 . GLU B 1 353 ? -42.377 29.547 35.948 1.00 51.13 ? 386 GLU B OE1 1 ATOM 6162 O OE2 . GLU B 1 353 ? -44.112 28.710 34.871 1.00 45.66 -1 386 GLU B OE2 1 ATOM 6163 N N . SER B 1 354 ? -44.483 33.667 36.080 1.00 22.85 ? 387 SER B N 1 ATOM 6164 C CA . SER B 1 354 ? -44.284 35.129 35.995 1.00 24.34 ? 387 SER B CA 1 ATOM 6165 C C . SER B 1 354 ? -45.534 35.939 35.495 1.00 25.03 ? 387 SER B C 1 ATOM 6166 O O . SER B 1 354 ? -46.064 36.797 36.224 1.00 23.81 ? 387 SER B O 1 ATOM 6167 C CB . SER B 1 354 ? -43.028 35.470 35.216 1.00 23.22 ? 387 SER B CB 1 ATOM 6168 O OG . SER B 1 354 ? -41.954 35.246 36.084 1.00 25.77 ? 387 SER B OG 1 ATOM 6169 N N . LEU B 1 355 ? -46.032 35.624 34.308 1.00 25.27 ? 388 LEU B N 1 ATOM 6170 C CA . LEU B 1 355 ? -47.246 36.253 33.824 1.00 26.90 ? 388 LEU B CA 1 ATOM 6171 C C . LEU B 1 355 ? -48.496 36.166 34.775 1.00 29.45 ? 388 LEU B C 1 ATOM 6172 O O . LEU B 1 355 ? -49.338 37.145 34.912 1.00 27.81 ? 388 LEU B O 1 ATOM 6173 C CB . LEU B 1 355 ? -47.593 35.628 32.481 1.00 27.07 ? 388 LEU B CB 1 ATOM 6174 C CG . LEU B 1 355 ? -46.762 36.108 31.341 1.00 24.83 ? 388 LEU B CG 1 ATOM 6175 C CD1 . LEU B 1 355 ? -47.513 35.833 30.063 1.00 24.49 ? 388 LEU B CD1 1 ATOM 6176 C CD2 . LEU B 1 355 ? -46.527 37.581 31.517 1.00 23.74 ? 388 LEU B CD2 1 ATOM 6177 N N . TYR B 1 356 ? -48.626 34.996 35.399 1.00 29.14 ? 389 TYR B N 1 ATOM 6178 C CA . TYR B 1 356 ? -49.655 34.756 36.420 1.00 30.95 ? 389 TYR B CA 1 ATOM 6179 C C . TYR B 1 356 ? -49.469 35.651 37.658 1.00 26.34 ? 389 TYR B C 1 ATOM 6180 O O . TYR B 1 356 ? -50.479 36.194 38.118 1.00 23.73 ? 389 TYR B O 1 ATOM 6181 C CB . TYR B 1 356 ? -49.648 33.305 36.875 1.00 34.70 ? 389 TYR B CB 1 ATOM 6182 C CG . TYR B 1 356 ? -50.890 32.904 37.620 1.00 37.02 ? 389 TYR B CG 1 ATOM 6183 C CD1 . TYR B 1 356 ? -52.097 32.806 36.944 1.00 36.73 ? 389 TYR B CD1 1 ATOM 6184 C CD2 . TYR B 1 356 ? -50.848 32.618 38.981 1.00 33.94 ? 389 TYR B CD2 1 ATOM 6185 C CE1 . TYR B 1 356 ? -53.217 32.389 37.590 1.00 38.48 ? 389 TYR B CE1 1 ATOM 6186 C CE2 . TYR B 1 356 ? -51.969 32.227 39.640 1.00 37.20 ? 389 TYR B CE2 1 ATOM 6187 C CZ . TYR B 1 356 ? -53.152 32.110 38.926 1.00 41.74 ? 389 TYR B CZ 1 ATOM 6188 O OH . TYR B 1 356 ? -54.322 31.720 39.538 1.00 53.80 ? 389 TYR B OH 1 ATOM 6189 N N . GLY B 1 357 ? -48.218 35.759 38.167 1.00 22.11 ? 390 GLY B N 1 ATOM 6190 C CA . GLY B 1 357 ? -47.824 36.769 39.146 1.00 21.21 ? 390 GLY B CA 1 ATOM 6191 C C . GLY B 1 357 ? -48.348 38.160 38.684 1.00 22.41 ? 390 GLY B C 1 ATOM 6192 O O . GLY B 1 357 ? -49.041 38.903 39.438 1.00 20.73 ? 390 GLY B O 1 ATOM 6193 N N . LEU B 1 358 ? -48.060 38.529 37.432 1.00 22.01 ? 391 LEU B N 1 ATOM 6194 C CA . LEU B 1 358 ? -48.571 39.811 36.874 1.00 21.51 ? 391 LEU B CA 1 ATOM 6195 C C . LEU B 1 358 ? -50.104 39.925 36.896 1.00 20.53 ? 391 LEU B C 1 ATOM 6196 O O . LEU B 1 358 ? -50.615 40.941 37.310 1.00 17.70 ? 391 LEU B O 1 ATOM 6197 C CB . LEU B 1 358 ? -48.087 40.055 35.413 1.00 21.80 ? 391 LEU B CB 1 ATOM 6198 C CG . LEU B 1 358 ? -48.356 41.450 34.787 1.00 20.47 ? 391 LEU B CG 1 ATOM 6199 C CD1 . LEU B 1 358 ? -47.845 42.571 35.687 1.00 20.79 ? 391 LEU B CD1 1 ATOM 6200 C CD2 . LEU B 1 358 ? -47.783 41.627 33.403 1.00 18.90 ? 391 LEU B CD2 1 ATOM 6201 N N . ALA B 1 359 ? -50.825 38.910 36.412 1.00 20.35 ? 392 ALA B N 1 ATOM 6202 C CA . ALA B 1 359 ? -52.258 39.019 36.344 1.00 19.35 ? 392 ALA B CA 1 ATOM 6203 C C . ALA B 1 359 ? -52.868 39.165 37.777 1.00 22.31 ? 392 ALA B C 1 ATOM 6204 O O . ALA B 1 359 ? -53.871 39.904 37.989 1.00 22.03 ? 392 ALA B O 1 ATOM 6205 C CB . ALA B 1 359 ? -52.848 37.866 35.533 1.00 17.72 ? 392 ALA B CB 1 ATOM 6206 N N . LYS B 1 360 ? -52.267 38.503 38.776 1.00 25.52 ? 393 LYS B N 1 ATOM 6207 C CA . LYS B 1 360 ? -52.716 38.680 40.193 1.00 28.07 ? 393 LYS B CA 1 ATOM 6208 C C . LYS B 1 360 ? -52.510 40.119 40.697 1.00 26.27 ? 393 LYS B C 1 ATOM 6209 O O . LYS B 1 360 ? -53.380 40.694 41.348 1.00 24.35 ? 393 LYS B O 1 ATOM 6210 C CB . LYS B 1 360 ? -52.007 37.720 41.149 1.00 30.49 ? 393 LYS B CB 1 ATOM 6211 C CG . LYS B 1 360 ? -52.535 36.296 41.046 1.00 35.15 ? 393 LYS B CG 1 ATOM 6212 C CD . LYS B 1 360 ? -54.026 36.195 41.412 1.00 38.92 ? 393 LYS B CD 1 ATOM 6213 C CE . LYS B 1 360 ? -54.470 34.750 41.685 1.00 40.14 ? 393 LYS B CE 1 ATOM 6214 N NZ . LYS B 1 360 ? -55.915 34.677 42.054 1.00 40.90 1 393 LYS B NZ 1 ATOM 6215 N N . GLN B 1 361 ? -51.362 40.696 40.376 1.00 23.83 ? 394 GLN B N 1 ATOM 6216 C CA . GLN B 1 361 ? -51.124 42.093 40.678 1.00 24.41 ? 394 GLN B CA 1 ATOM 6217 C C . GLN B 1 361 ? -52.164 43.034 40.165 1.00 23.19 ? 394 GLN B C 1 ATOM 6218 O O . GLN B 1 361 ? -52.388 44.014 40.840 1.00 22.64 ? 394 GLN B O 1 ATOM 6219 C CB . GLN B 1 361 ? -49.756 42.559 40.189 1.00 26.28 ? 394 GLN B CB 1 ATOM 6220 C CG . GLN B 1 361 ? -48.581 42.083 41.033 1.00 27.73 ? 394 GLN B CG 1 ATOM 6221 C CD . GLN B 1 361 ? -47.335 42.651 40.462 1.00 34.36 ? 394 GLN B CD 1 ATOM 6222 O OE1 . GLN B 1 361 ? -46.664 41.971 39.711 1.00 38.73 ? 394 GLN B OE1 1 ATOM 6223 N NE2 . GLN B 1 361 ? -47.045 43.958 40.735 1.00 40.66 ? 394 GLN B NE2 1 ATOM 6224 N N . PHE B 1 362 ? -52.761 42.752 38.989 1.00 23.20 ? 395 PHE B N 1 ATOM 6225 C CA . PHE B 1 362 ? -53.811 43.610 38.347 1.00 23.12 ? 395 PHE B CA 1 ATOM 6226 C C . PHE B 1 362 ? -55.114 43.615 39.127 1.00 25.56 ? 395 PHE B C 1 ATOM 6227 O O . PHE B 1 362 ? -55.853 44.616 39.091 1.00 26.08 ? 395 PHE B O 1 ATOM 6228 C CB . PHE B 1 362 ? -54.270 43.109 37.003 1.00 20.61 ? 395 PHE B CB 1 ATOM 6229 C CG . PHE B 1 362 ? -53.267 43.099 35.963 1.00 19.81 ? 395 PHE B CG 1 ATOM 6230 C CD1 . PHE B 1 362 ? -52.144 43.904 36.030 1.00 19.80 ? 395 PHE B CD1 1 ATOM 6231 C CD2 . PHE B 1 362 ? -53.477 42.290 34.839 1.00 19.71 ? 395 PHE B CD2 1 ATOM 6232 C CE1 . PHE B 1 362 ? -51.227 43.927 34.956 1.00 20.70 ? 395 PHE B CE1 1 ATOM 6233 C CE2 . PHE B 1 362 ? -52.566 42.291 33.766 1.00 21.04 ? 395 PHE B CE2 1 ATOM 6234 C CZ . PHE B 1 362 ? -51.432 43.106 33.831 1.00 21.02 ? 395 PHE B CZ 1 ATOM 6235 N N . THR B 1 363 ? -55.415 42.470 39.763 1.00 26.68 ? 396 THR B N 1 ATOM 6236 C CA . THR B 1 363 ? -56.577 42.310 40.691 1.00 27.22 ? 396 THR B CA 1 ATOM 6237 C C . THR B 1 363 ? -56.481 43.097 42.026 1.00 27.24 ? 396 THR B C 1 ATOM 6238 O O . THR B 1 363 ? -57.359 42.960 42.879 1.00 27.34 ? 396 THR B O 1 ATOM 6239 C CB . THR B 1 363 ? -56.832 40.834 41.067 1.00 28.65 ? 396 THR B CB 1 ATOM 6240 O OG1 . THR B 1 363 ? -55.934 40.419 42.101 1.00 26.10 ? 396 THR B OG1 1 ATOM 6241 C CG2 . THR B 1 363 ? -56.669 39.930 39.860 1.00 33.05 ? 396 THR B CG2 1 ATOM 6242 N N . ILE B 1 364 ? -55.381 43.841 42.205 1.00 27.60 ? 397 ILE B N 1 ATOM 6243 C CA . ILE B 1 364 ? -55.215 44.809 43.251 1.00 26.31 ? 397 ILE B CA 1 ATOM 6244 C C . ILE B 1 364 ? -56.151 45.982 43.027 1.00 25.03 ? 397 ILE B C 1 ATOM 6245 O O . ILE B 1 364 ? -56.366 46.455 41.927 1.00 19.59 ? 397 ILE B O 1 ATOM 6246 C CB . ILE B 1 364 ? -53.756 45.281 43.311 1.00 27.62 ? 397 ILE B CB 1 ATOM 6247 C CG1 . ILE B 1 364 ? -52.891 44.122 43.851 1.00 26.53 ? 397 ILE B CG1 1 ATOM 6248 C CG2 . ILE B 1 364 ? -53.584 46.639 44.048 1.00 25.97 ? 397 ILE B CG2 1 ATOM 6249 C CD1 . ILE B 1 364 ? -51.411 44.480 43.814 1.00 26.31 ? 397 ILE B CD1 1 ATOM 6250 N N . LEU B 1 365 ? -56.732 46.390 44.146 1.00 30.90 ? 398 LEU B N 1 ATOM 6251 C CA . LEU B 1 365 ? -57.708 47.461 44.223 1.00 34.56 ? 398 LEU B CA 1 ATOM 6252 C C . LEU B 1 365 ? -56.932 48.715 43.807 1.00 32.48 ? 398 LEU B C 1 ATOM 6253 O O . LEU B 1 365 ? -55.972 49.143 44.505 1.00 30.12 ? 398 LEU B O 1 ATOM 6254 C CB . LEU B 1 365 ? -58.308 47.509 45.648 1.00 36.73 ? 398 LEU B CB 1 ATOM 6255 C CG . LEU B 1 365 ? -59.304 48.602 46.108 1.00 39.94 ? 398 LEU B CG 1 ATOM 6256 C CD1 . LEU B 1 365 ? -60.326 49.013 45.042 1.00 39.93 ? 398 LEU B CD1 1 ATOM 6257 C CD2 . LEU B 1 365 ? -60.009 48.125 47.387 1.00 39.47 ? 398 LEU B CD2 1 ATOM 6258 N N . ASP B 1 366 ? -57.285 49.215 42.614 1.00 29.36 ? 399 ASP B N 1 ATOM 6259 C CA . ASP B 1 366 ? -56.611 50.372 41.976 1.00 29.10 ? 399 ASP B CA 1 ATOM 6260 C C . ASP B 1 366 ? -55.123 50.089 41.557 1.00 26.11 ? 399 ASP B C 1 ATOM 6261 O O . ASP B 1 366 ? -54.241 50.967 41.612 1.00 24.81 ? 399 ASP B O 1 ATOM 6262 C CB . ASP B 1 366 ? -56.773 51.640 42.832 1.00 32.88 ? 399 ASP B CB 1 ATOM 6263 C CG . ASP B 1 366 ? -58.271 51.982 43.131 1.00 41.03 ? 399 ASP B CG 1 ATOM 6264 O OD1 . ASP B 1 366 ? -59.226 51.411 42.507 1.00 43.88 ? 399 ASP B OD1 1 ATOM 6265 O OD2 . ASP B 1 366 ? -58.505 52.846 44.019 1.00 50.39 -1 399 ASP B OD2 1 ATOM 6266 N N . SER B 1 367 ? -54.902 48.853 41.119 1.00 22.51 ? 400 SER B N 1 ATOM 6267 C CA . SER B 1 367 ? -53.699 48.436 40.534 1.00 22.43 ? 400 SER B CA 1 ATOM 6268 C C . SER B 1 367 ? -53.214 49.432 39.476 1.00 25.86 ? 400 SER B C 1 ATOM 6269 O O . SER B 1 367 ? -53.782 49.537 38.364 1.00 30.37 ? 400 SER B O 1 ATOM 6270 C CB . SER B 1 367 ? -53.898 47.087 39.869 1.00 22.18 ? 400 SER B CB 1 ATOM 6271 O OG . SER B 1 367 ? -52.704 46.705 39.179 1.00 25.50 ? 400 SER B OG 1 ATOM 6272 N N . LYS B 1 368 ? -52.156 50.151 39.823 1.00 25.73 ? 401 LYS B N 1 ATOM 6273 C CA . LYS B 1 368 ? -51.329 50.776 38.829 1.00 27.41 ? 401 LYS B CA 1 ATOM 6274 C C . LYS B 1 368 ? -50.926 49.850 37.665 1.00 21.56 ? 401 LYS B C 1 ATOM 6275 O O . LYS B 1 368 ? -50.835 50.294 36.531 1.00 15.36 ? 401 LYS B O 1 ATOM 6276 C CB . LYS B 1 368 ? -50.099 51.407 39.487 1.00 32.28 ? 401 LYS B CB 1 ATOM 6277 C CG . LYS B 1 368 ? -50.349 52.883 39.869 1.00 40.72 ? 401 LYS B CG 1 ATOM 6278 C CD . LYS B 1 368 ? -51.716 53.142 40.558 1.00 47.10 ? 401 LYS B CD 1 ATOM 6279 C CE . LYS B 1 368 ? -52.348 54.502 40.222 1.00 48.61 ? 401 LYS B CE 1 ATOM 6280 N NZ . LYS B 1 368 ? -53.738 54.600 40.771 1.00 47.40 1 401 LYS B NZ 1 ATOM 6281 N N . GLN B 1 369 ? -50.742 48.575 37.954 1.00 21.57 ? 402 GLN B N 1 ATOM 6282 C CA . GLN B 1 369 ? -50.320 47.630 36.895 1.00 25.03 ? 402 GLN B CA 1 ATOM 6283 C C . GLN B 1 369 ? -51.447 47.521 35.839 1.00 24.94 ? 402 GLN B C 1 ATOM 6284 O O . GLN B 1 369 ? -51.146 47.511 34.613 1.00 27.82 ? 402 GLN B O 1 ATOM 6285 C CB . GLN B 1 369 ? -49.935 46.191 37.387 1.00 24.55 ? 402 GLN B CB 1 ATOM 6286 C CG . GLN B 1 369 ? -48.845 46.026 38.434 1.00 26.79 ? 402 GLN B CG 1 ATOM 6287 C CD . GLN B 1 369 ? -47.508 45.911 37.795 1.00 31.68 ? 402 GLN B CD 1 ATOM 6288 O OE1 . GLN B 1 369 ? -47.190 46.741 36.935 1.00 42.53 ? 402 GLN B OE1 1 ATOM 6289 N NE2 . GLN B 1 369 ? -46.705 44.893 38.172 1.00 30.37 ? 402 GLN B NE2 1 ATOM 6290 N N . PHE B 1 370 ? -52.704 47.437 36.291 1.00 19.86 ? 403 PHE B N 1 ATOM 6291 C CA . PHE B 1 370 ? -53.731 47.124 35.374 1.00 19.76 ? 403 PHE B CA 1 ATOM 6292 C C . PHE B 1 370 ? -53.990 48.286 34.432 1.00 19.89 ? 403 PHE B C 1 ATOM 6293 O O . PHE B 1 370 ? -54.228 48.085 33.199 1.00 15.54 ? 403 PHE B O 1 ATOM 6294 C CB . PHE B 1 370 ? -55.065 46.798 36.052 1.00 21.07 ? 403 PHE B CB 1 ATOM 6295 C CG . PHE B 1 370 ? -56.155 46.611 35.045 1.00 21.94 ? 403 PHE B CG 1 ATOM 6296 C CD1 . PHE B 1 370 ? -56.042 45.598 34.089 1.00 23.15 ? 403 PHE B CD1 1 ATOM 6297 C CD2 . PHE B 1 370 ? -57.205 47.515 34.939 1.00 22.31 ? 403 PHE B CD2 1 ATOM 6298 C CE1 . PHE B 1 370 ? -56.984 45.457 33.081 1.00 24.87 ? 403 PHE B CE1 1 ATOM 6299 C CE2 . PHE B 1 370 ? -58.150 47.378 33.936 1.00 23.13 ? 403 PHE B CE2 1 ATOM 6300 C CZ . PHE B 1 370 ? -58.037 46.360 32.998 1.00 24.85 ? 403 PHE B CZ 1 ATOM 6301 N N . ILE B 1 371 ? -54.079 49.463 35.079 1.00 19.28 ? 404 ILE B N 1 ATOM 6302 C CA . ILE B 1 371 ? -54.053 50.741 34.433 1.00 19.44 ? 404 ILE B CA 1 ATOM 6303 C C . ILE B 1 371 ? -53.031 50.846 33.281 1.00 16.54 ? 404 ILE B C 1 ATOM 6304 O O . ILE B 1 371 ? -53.328 51.238 32.198 1.00 12.25 ? 404 ILE B O 1 ATOM 6305 C CB . ILE B 1 371 ? -53.802 51.770 35.523 1.00 23.57 ? 404 ILE B CB 1 ATOM 6306 C CG1 . ILE B 1 371 ? -55.168 52.289 35.978 1.00 29.98 ? 404 ILE B CG1 1 ATOM 6307 C CG2 . ILE B 1 371 ? -52.997 52.976 35.078 1.00 24.30 ? 404 ILE B CG2 1 ATOM 6308 C CD1 . ILE B 1 371 ? -55.911 53.143 34.908 1.00 31.30 ? 404 ILE B CD1 1 ATOM 6309 N N . LYS B 1 372 ? -51.830 50.451 33.564 1.00 16.05 ? 405 LYS B N 1 ATOM 6310 C CA . LYS B 1 372 ? -50.835 50.330 32.575 1.00 17.89 ? 405 LYS B CA 1 ATOM 6311 C C . LYS B 1 372 ? -51.306 49.387 31.438 1.00 17.79 ? 405 LYS B C 1 ATOM 6312 O O . LYS B 1 372 ? -51.288 49.752 30.195 1.00 17.41 ? 405 LYS B O 1 ATOM 6313 C CB . LYS B 1 372 ? -49.568 49.752 33.208 1.00 20.19 ? 405 LYS B CB 1 ATOM 6314 C CG . LYS B 1 372 ? -48.508 50.777 33.442 1.00 22.98 ? 405 LYS B CG 1 ATOM 6315 C CD . LYS B 1 372 ? -47.156 50.106 33.593 1.00 27.99 ? 405 LYS B CD 1 ATOM 6316 C CE . LYS B 1 372 ? -46.029 51.138 33.551 1.00 30.08 ? 405 LYS B CE 1 ATOM 6317 N NZ . LYS B 1 372 ? -44.802 50.687 34.278 1.00 30.07 1 405 LYS B NZ 1 ATOM 6318 N N . TYR B 1 373 ? -51.696 48.208 31.877 1.00 14.41 ? 406 TYR B N 1 ATOM 6319 C CA . TYR B 1 373 ? -52.123 47.207 31.008 1.00 16.00 ? 406 TYR B CA 1 ATOM 6320 C C . TYR B 1 373 ? -53.323 47.675 30.106 1.00 16.42 ? 406 TYR B C 1 ATOM 6321 O O . TYR B 1 373 ? -53.376 47.320 28.900 1.00 16.93 ? 406 TYR B O 1 ATOM 6322 C CB . TYR B 1 373 ? -52.469 45.917 31.810 1.00 18.07 ? 406 TYR B CB 1 ATOM 6323 C CG . TYR B 1 373 ? -52.977 44.826 30.915 1.00 18.49 ? 406 TYR B CG 1 ATOM 6324 C CD1 . TYR B 1 373 ? -52.111 44.007 30.286 1.00 19.82 ? 406 TYR B CD1 1 ATOM 6325 C CD2 . TYR B 1 373 ? -54.299 44.720 30.630 1.00 19.22 ? 406 TYR B CD2 1 ATOM 6326 C CE1 . TYR B 1 373 ? -52.543 43.037 29.435 1.00 21.72 ? 406 TYR B CE1 1 ATOM 6327 C CE2 . TYR B 1 373 ? -54.746 43.796 29.738 1.00 21.84 ? 406 TYR B CE2 1 ATOM 6328 C CZ . TYR B 1 373 ? -53.845 42.954 29.131 1.00 22.73 ? 406 TYR B CZ 1 ATOM 6329 O OH . TYR B 1 373 ? -54.261 41.968 28.270 1.00 23.57 ? 406 TYR B OH 1 ATOM 6330 N N . TYR B 1 374 ? -54.245 48.439 30.672 1.00 14.50 ? 407 TYR B N 1 ATOM 6331 C CA . TYR B 1 374 ? -55.234 49.095 29.899 1.00 14.59 ? 407 TYR B CA 1 ATOM 6332 C C . TYR B 1 374 ? -54.684 50.124 28.868 1.00 13.84 ? 407 TYR B C 1 ATOM 6333 O O . TYR B 1 374 ? -55.172 50.236 27.799 1.00 15.08 ? 407 TYR B O 1 ATOM 6334 C CB . TYR B 1 374 ? -56.277 49.778 30.790 1.00 15.26 ? 407 TYR B CB 1 ATOM 6335 C CG . TYR B 1 374 ? -57.671 49.671 30.191 1.00 16.57 ? 407 TYR B CG 1 ATOM 6336 C CD1 . TYR B 1 374 ? -58.235 48.430 29.876 1.00 18.15 ? 407 TYR B CD1 1 ATOM 6337 C CD2 . TYR B 1 374 ? -58.385 50.774 29.888 1.00 16.95 ? 407 TYR B CD2 1 ATOM 6338 C CE1 . TYR B 1 374 ? -59.478 48.344 29.286 1.00 18.06 ? 407 TYR B CE1 1 ATOM 6339 C CE2 . TYR B 1 374 ? -59.645 50.694 29.333 1.00 17.01 ? 407 TYR B CE2 1 ATOM 6340 C CZ . TYR B 1 374 ? -60.186 49.493 29.027 1.00 18.05 ? 407 TYR B CZ 1 ATOM 6341 O OH . TYR B 1 374 ? -61.456 49.471 28.428 1.00 20.20 ? 407 TYR B OH 1 ATOM 6342 N N . ASN B 1 375 ? -53.654 50.827 29.160 1.00 13.19 ? 408 ASN B N 1 ATOM 6343 C CA A ASN B 1 375 ? -53.145 51.792 28.252 0.50 13.16 ? 408 ASN B CA 1 ATOM 6344 C CA B ASN B 1 375 ? -53.133 51.797 28.244 0.50 14.57 ? 408 ASN B CA 1 ATOM 6345 C C . ASN B 1 375 ? -52.532 51.053 27.046 1.00 15.04 ? 408 ASN B C 1 ATOM 6346 O O . ASN B 1 375 ? -52.887 51.343 25.812 1.00 15.93 ? 408 ASN B O 1 ATOM 6347 C CB A ASN B 1 375 ? -52.093 52.673 28.976 0.50 12.43 ? 408 ASN B CB 1 ATOM 6348 C CB B ASN B 1 375 ? -52.064 52.699 28.935 0.50 15.79 ? 408 ASN B CB 1 ATOM 6349 C CG A ASN B 1 375 ? -52.704 53.918 29.602 0.50 10.99 ? 408 ASN B CG 1 ATOM 6350 C CG B ASN B 1 375 ? -50.810 52.882 28.081 0.50 16.29 ? 408 ASN B CG 1 ATOM 6351 O OD1 A ASN B 1 375 ? -53.822 54.306 29.290 0.50 10.06 ? 408 ASN B OD1 1 ATOM 6352 O OD1 B ASN B 1 375 ? -49.917 52.075 28.170 0.50 18.15 ? 408 ASN B OD1 1 ATOM 6353 N ND2 A ASN B 1 375 ? -51.950 54.554 30.448 0.50 10.22 ? 408 ASN B ND2 1 ATOM 6354 N ND2 B ASN B 1 375 ? -50.757 53.918 27.244 0.50 16.25 ? 408 ASN B ND2 1 ATOM 6355 N N . TYR B 1 376 ? -51.636 50.104 27.377 1.00 13.56 ? 409 TYR B N 1 ATOM 6356 C CA . TYR B 1 376 ? -50.962 49.387 26.395 1.00 12.89 ? 409 TYR B CA 1 ATOM 6357 C C . TYR B 1 376 ? -51.962 48.570 25.501 1.00 12.93 ? 409 TYR B C 1 ATOM 6358 O O . TYR B 1 376 ? -51.677 48.316 24.297 1.00 12.71 ? 409 TYR B O 1 ATOM 6359 C CB . TYR B 1 376 ? -49.979 48.444 27.041 1.00 13.59 ? 409 TYR B CB 1 ATOM 6360 C CG . TYR B 1 376 ? -48.805 49.052 27.709 1.00 14.93 ? 409 TYR B CG 1 ATOM 6361 C CD1 . TYR B 1 376 ? -48.221 50.208 27.224 1.00 15.54 ? 409 TYR B CD1 1 ATOM 6362 C CD2 . TYR B 1 376 ? -48.265 48.480 28.891 1.00 15.95 ? 409 TYR B CD2 1 ATOM 6363 C CE1 . TYR B 1 376 ? -47.110 50.796 27.869 1.00 16.43 ? 409 TYR B CE1 1 ATOM 6364 C CE2 . TYR B 1 376 ? -47.178 49.065 29.531 1.00 17.06 ? 409 TYR B CE2 1 ATOM 6365 C CZ . TYR B 1 376 ? -46.576 50.222 29.018 1.00 17.54 ? 409 TYR B CZ 1 ATOM 6366 O OH . TYR B 1 376 ? -45.429 50.821 29.622 1.00 18.66 ? 409 TYR B OH 1 ATOM 6367 N N . PHE B 1 377 ? -53.084 48.108 26.060 1.00 11.80 ? 410 PHE B N 1 ATOM 6368 C CA . PHE B 1 377 ? -54.090 47.313 25.273 1.00 11.23 ? 410 PHE B CA 1 ATOM 6369 C C . PHE B 1 377 ? -54.609 48.040 24.007 1.00 11.40 ? 410 PHE B C 1 ATOM 6370 O O . PHE B 1 377 ? -54.797 47.454 22.979 1.00 10.59 ? 410 PHE B O 1 ATOM 6371 C CB . PHE B 1 377 ? -55.235 46.992 26.197 1.00 10.35 ? 410 PHE B CB 1 ATOM 6372 C CG . PHE B 1 377 ? -56.318 46.182 25.620 1.00 9.51 ? 410 PHE B CG 1 ATOM 6373 C CD1 . PHE B 1 377 ? -56.188 44.827 25.518 1.00 9.05 ? 410 PHE B CD1 1 ATOM 6374 C CD2 . PHE B 1 377 ? -57.580 46.803 25.321 1.00 9.79 ? 410 PHE B CD2 1 ATOM 6375 C CE1 . PHE B 1 377 ? -57.278 44.037 25.053 1.00 9.75 ? 410 PHE B CE1 1 ATOM 6376 C CE2 . PHE B 1 377 ? -58.666 46.014 24.865 1.00 10.14 ? 410 PHE B CE2 1 ATOM 6377 C CZ . PHE B 1 377 ? -58.518 44.608 24.743 1.00 9.59 ? 410 PHE B CZ 1 ATOM 6378 N N . PHE B 1 378 ? -54.805 49.329 24.112 1.00 12.02 ? 411 PHE B N 1 ATOM 6379 C CA . PHE B 1 378 ? -55.066 50.097 22.947 1.00 13.26 ? 411 PHE B CA 1 ATOM 6380 C C . PHE B 1 378 ? -53.827 50.584 22.227 1.00 13.80 ? 411 PHE B C 1 ATOM 6381 O O . PHE B 1 378 ? -53.969 51.560 21.468 1.00 15.50 ? 411 PHE B O 1 ATOM 6382 C CB . PHE B 1 378 ? -55.809 51.326 23.389 1.00 13.51 ? 411 PHE B CB 1 ATOM 6383 C CG . PHE B 1 378 ? -57.108 50.970 24.008 1.00 14.64 ? 411 PHE B CG 1 ATOM 6384 C CD1 . PHE B 1 378 ? -58.130 50.382 23.179 1.00 14.64 ? 411 PHE B CD1 1 ATOM 6385 C CD2 . PHE B 1 378 ? -57.314 51.148 25.381 1.00 13.04 ? 411 PHE B CD2 1 ATOM 6386 C CE1 . PHE B 1 378 ? -59.341 49.974 23.730 1.00 14.93 ? 411 PHE B CE1 1 ATOM 6387 C CE2 . PHE B 1 378 ? -58.517 50.782 25.904 1.00 14.50 ? 411 PHE B CE2 1 ATOM 6388 C CZ . PHE B 1 378 ? -59.533 50.167 25.108 1.00 15.11 ? 411 PHE B CZ 1 ATOM 6389 N N . VAL B 1 379 ? -52.641 50.029 22.552 1.00 12.22 ? 412 VAL B N 1 ATOM 6390 C CA . VAL B 1 379 ? -51.349 50.537 22.124 1.00 11.14 ? 412 VAL B CA 1 ATOM 6391 C C . VAL B 1 379 ? -51.250 51.990 22.269 1.00 10.60 ? 412 VAL B C 1 ATOM 6392 O O . VAL B 1 379 ? -50.860 52.711 21.312 1.00 9.32 ? 412 VAL B O 1 ATOM 6393 C CB . VAL B 1 379 ? -51.031 50.126 20.673 1.00 11.26 ? 412 VAL B CB 1 ATOM 6394 C CG1 . VAL B 1 379 ? -49.628 50.497 20.329 1.00 10.90 ? 412 VAL B CG1 1 ATOM 6395 C CG2 . VAL B 1 379 ? -51.172 48.584 20.535 1.00 11.98 ? 412 VAL B CG2 1 ATOM 6396 N N . SER B 1 380 ? -51.611 52.409 23.462 1.00 11.41 ? 413 SER B N 1 ATOM 6397 C CA . SER B 1 380 ? -51.513 53.790 23.925 1.00 13.81 ? 413 SER B CA 1 ATOM 6398 C C . SER B 1 380 ? -52.233 54.874 23.137 1.00 15.95 ? 413 SER B C 1 ATOM 6399 O O . SER B 1 380 ? -51.883 56.009 23.245 1.00 15.61 ? 413 SER B O 1 ATOM 6400 C CB . SER B 1 380 ? -50.048 54.196 24.033 1.00 13.85 ? 413 SER B CB 1 ATOM 6401 O OG . SER B 1 380 ? -49.352 53.318 24.860 1.00 15.50 ? 413 SER B OG 1 ATOM 6402 N N . TYR B 1 381 ? -53.230 54.502 22.353 1.00 19.79 ? 414 TYR B N 1 ATOM 6403 C CA . TYR B 1 381 ? -54.044 55.406 21.559 1.00 24.49 ? 414 TYR B CA 1 ATOM 6404 C C . TYR B 1 381 ? -54.662 56.576 22.344 1.00 29.48 ? 414 TYR B C 1 ATOM 6405 O O . TYR B 1 381 ? -54.651 57.700 21.855 1.00 33.66 ? 414 TYR B O 1 ATOM 6406 C CB . TYR B 1 381 ? -55.079 54.623 20.768 1.00 23.70 ? 414 TYR B CB 1 ATOM 6407 C CG . TYR B 1 381 ? -56.072 55.456 20.013 1.00 23.11 ? 414 TYR B CG 1 ATOM 6408 C CD1 . TYR B 1 381 ? -55.739 56.011 18.794 1.00 24.14 ? 414 TYR B CD1 1 ATOM 6409 C CD2 . TYR B 1 381 ? -57.338 55.704 20.522 1.00 22.29 ? 414 TYR B CD2 1 ATOM 6410 C CE1 . TYR B 1 381 ? -56.656 56.742 18.083 1.00 23.49 ? 414 TYR B CE1 1 ATOM 6411 C CE2 . TYR B 1 381 ? -58.233 56.450 19.832 1.00 22.15 ? 414 TYR B CE2 1 ATOM 6412 C CZ . TYR B 1 381 ? -57.873 56.938 18.606 1.00 23.80 ? 414 TYR B CZ 1 ATOM 6413 O OH . TYR B 1 381 ? -58.701 57.676 17.883 1.00 29.70 ? 414 TYR B OH 1 ATOM 6414 N N . ASP B 1 382 ? -55.182 56.348 23.536 1.00 35.36 ? 415 ASP B N 1 ATOM 6415 C CA . ASP B 1 382 ? -55.501 57.490 24.382 1.00 42.66 ? 415 ASP B CA 1 ATOM 6416 C C . ASP B 1 382 ? -54.847 57.315 25.744 1.00 47.50 ? 415 ASP B C 1 ATOM 6417 O O . ASP B 1 382 ? -55.208 56.396 26.474 1.00 52.03 ? 415 ASP B O 1 ATOM 6418 C CB . ASP B 1 382 ? -57.012 57.762 24.477 1.00 48.02 ? 415 ASP B CB 1 ATOM 6419 C CG . ASP B 1 382 ? -57.430 59.101 23.833 1.00 54.21 ? 415 ASP B CG 1 ATOM 6420 O OD1 . ASP B 1 382 ? -56.570 59.924 23.443 1.00 51.48 ? 415 ASP B OD1 1 ATOM 6421 O OD2 . ASP B 1 382 ? -58.646 59.341 23.716 1.00 50.28 -1 415 ASP B OD2 1 ATOM 6422 N N . SER B 1 383 ? -53.849 58.147 26.054 1.00 50.82 ? 416 SER B N 1 ATOM 6423 C CA . SER B 1 383 ? -53.333 58.289 27.408 1.00 52.14 ? 416 SER B CA 1 ATOM 6424 C C . SER B 1 383 ? -54.340 58.076 28.543 1.00 51.21 ? 416 SER B C 1 ATOM 6425 O O . SER B 1 383 ? -54.283 57.130 29.323 1.00 52.50 ? 416 SER B O 1 ATOM 6426 C CB . SER B 1 383 ? -52.878 59.741 27.585 1.00 54.72 ? 416 SER B CB 1 ATOM 6427 O OG . SER B 1 383 ? -51.631 59.983 26.980 1.00 68.56 ? 416 SER B OG 1 ATOM 6428 N N . SER B 1 384 ? -55.335 58.947 28.529 1.00 53.70 ? 417 SER B N 1 ATOM 6429 C CA . SER B 1 384 ? -56.198 59.210 29.654 1.00 56.27 ? 417 SER B CA 1 ATOM 6430 C C . SER B 1 384 ? -57.376 58.300 29.493 1.00 51.74 ? 417 SER B C 1 ATOM 6431 O O . SER B 1 384 ? -58.500 58.668 29.849 1.00 53.95 ? 417 SER B O 1 ATOM 6432 C CB . SER B 1 384 ? -56.691 60.670 29.666 1.00 57.87 ? 417 SER B CB 1 ATOM 6433 O OG . SER B 1 384 ? -57.519 60.924 28.539 1.00 58.09 ? 417 SER B OG 1 ATOM 6434 N N . VAL B 1 385 ? -57.132 57.110 28.956 1.00 49.51 ? 418 VAL B N 1 ATOM 6435 C CA . VAL B 1 385 ? -58.235 56.169 28.699 1.00 44.79 ? 418 VAL B CA 1 ATOM 6436 C C . VAL B 1 385 ? -58.459 55.474 29.991 1.00 36.37 ? 418 VAL B C 1 ATOM 6437 O O . VAL B 1 385 ? -57.576 54.840 30.545 1.00 35.71 ? 418 VAL B O 1 ATOM 6438 C CB . VAL B 1 385 ? -57.968 55.162 27.547 1.00 44.23 ? 418 VAL B CB 1 ATOM 6439 C CG1 . VAL B 1 385 ? -57.619 55.952 26.323 1.00 40.55 ? 418 VAL B CG1 1 ATOM 6440 C CG2 . VAL B 1 385 ? -56.874 54.126 27.868 1.00 45.99 ? 418 VAL B CG2 1 ATOM 6441 N N . THR B 1 386 ? -59.621 55.664 30.528 1.00 31.07 ? 419 THR B N 1 ATOM 6442 C CA . THR B 1 386 ? -59.826 55.134 31.847 1.00 31.64 ? 419 THR B CA 1 ATOM 6443 C C . THR B 1 386 ? -60.545 53.833 31.568 1.00 28.72 ? 419 THR B C 1 ATOM 6444 O O . THR B 1 386 ? -60.710 53.443 30.400 1.00 27.62 ? 419 THR B O 1 ATOM 6445 C CB . THR B 1 386 ? -60.534 56.180 32.787 1.00 30.27 ? 419 THR B CB 1 ATOM 6446 O OG1 . THR B 1 386 ? -60.766 55.639 34.077 1.00 26.50 ? 419 THR B OG1 1 ATOM 6447 C CG2 . THR B 1 386 ? -61.840 56.672 32.201 1.00 30.04 ? 419 THR B CG2 1 ATOM 6448 N N . CYS B 1 387 ? -60.933 53.183 32.654 1.00 28.80 ? 420 CYS B N 1 ATOM 6449 C CA . CYS B 1 387 ? -61.556 51.849 32.672 1.00 28.80 ? 420 CYS B CA 1 ATOM 6450 C C . CYS B 1 387 ? -62.443 51.783 33.937 1.00 27.18 ? 420 CYS B C 1 ATOM 6451 O O . CYS B 1 387 ? -62.034 52.270 34.990 1.00 24.92 ? 420 CYS B O 1 ATOM 6452 C CB . CYS B 1 387 ? -60.443 50.771 32.729 1.00 27.31 ? 420 CYS B CB 1 ATOM 6453 S SG . CYS B 1 387 ? -61.093 49.125 32.500 1.00 28.30 ? 420 CYS B SG 1 ATOM 6454 N N . ASP B 1 388 ? -63.645 51.229 33.833 1.00 25.92 ? 421 ASP B N 1 ATOM 6455 C CA . ASP B 1 388 ? -64.531 51.104 35.014 1.00 26.87 ? 421 ASP B CA 1 ATOM 6456 C C . ASP B 1 388 ? -64.475 49.669 35.570 1.00 26.86 ? 421 ASP B C 1 ATOM 6457 O O . ASP B 1 388 ? -63.901 48.804 34.894 1.00 32.65 ? 421 ASP B O 1 ATOM 6458 C CB . ASP B 1 388 ? -65.958 51.488 34.628 1.00 27.81 ? 421 ASP B CB 1 ATOM 6459 C CG . ASP B 1 388 ? -66.562 50.531 33.646 1.00 29.15 ? 421 ASP B CG 1 ATOM 6460 O OD1 . ASP B 1 388 ? -65.997 50.330 32.525 1.00 33.65 ? 421 ASP B OD1 1 ATOM 6461 O OD2 . ASP B 1 388 ? -67.594 49.983 34.016 1.00 27.31 -1 421 ASP B OD2 1 ATOM 6462 N N . LYS B 1 389 ? -65.077 49.409 36.742 1.00 23.96 ? 422 LYS B N 1 ATOM 6463 C CA . LYS B 1 389 ? -64.977 48.111 37.395 1.00 24.73 ? 422 LYS B CA 1 ATOM 6464 C C . LYS B 1 389 ? -65.419 46.918 36.578 1.00 23.44 ? 422 LYS B C 1 ATOM 6465 O O . LYS B 1 389 ? -64.820 45.870 36.686 1.00 27.26 ? 422 LYS B O 1 ATOM 6466 C CB . LYS B 1 389 ? -65.804 48.040 38.655 1.00 30.02 ? 422 LYS B CB 1 ATOM 6467 C CG . LYS B 1 389 ? -65.402 49.009 39.738 1.00 37.27 ? 422 LYS B CG 1 ATOM 6468 C CD . LYS B 1 389 ? -66.524 49.247 40.758 1.00 42.62 ? 422 LYS B CD 1 ATOM 6469 C CE . LYS B 1 389 ? -67.901 49.292 40.128 1.00 45.31 ? 422 LYS B CE 1 ATOM 6470 N NZ . LYS B 1 389 ? -68.839 50.154 40.884 1.00 49.72 1 422 LYS B NZ 1 ATOM 6471 N N . THR B 1 390 ? -66.495 47.038 35.826 1.00 20.06 ? 423 THR B N 1 ATOM 6472 C CA . THR B 1 390 ? -67.008 45.971 35.001 1.00 19.92 ? 423 THR B CA 1 ATOM 6473 C C . THR B 1 390 ? -66.044 45.546 33.848 1.00 20.73 ? 423 THR B C 1 ATOM 6474 O O . THR B 1 390 ? -65.839 44.337 33.553 1.00 17.74 ? 423 THR B O 1 ATOM 6475 C CB . THR B 1 390 ? -68.354 46.453 34.408 1.00 21.35 ? 423 THR B CB 1 ATOM 6476 O OG1 . THR B 1 390 ? -69.131 47.011 35.456 1.00 23.09 ? 423 THR B OG1 1 ATOM 6477 C CG2 . THR B 1 390 ? -69.166 45.331 33.752 1.00 21.94 ? 423 THR B CG2 1 ATOM 6478 N N . CYS B 1 391 ? -65.498 46.555 33.164 1.00 23.43 ? 424 CYS B N 1 ATOM 6479 C CA . CYS B 1 391 ? -64.505 46.293 32.120 1.00 25.47 ? 424 CYS B CA 1 ATOM 6480 C C . CYS B 1 391 ? -63.289 45.598 32.753 1.00 21.85 ? 424 CYS B C 1 ATOM 6481 O O . CYS B 1 391 ? -62.859 44.583 32.216 1.00 18.04 ? 424 CYS B O 1 ATOM 6482 C CB . CYS B 1 391 ? -64.111 47.571 31.318 1.00 28.09 ? 424 CYS B CB 1 ATOM 6483 S SG . CYS B 1 391 ? -65.423 48.056 30.139 1.00 37.53 ? 424 CYS B SG 1 ATOM 6484 N N . LYS B 1 392 ? -62.795 46.120 33.902 1.00 18.98 ? 425 LYS B N 1 ATOM 6485 C CA . LYS B 1 392 ? -61.672 45.481 34.570 1.00 19.71 ? 425 LYS B CA 1 ATOM 6486 C C . LYS B 1 392 ? -61.950 44.008 34.870 1.00 19.90 ? 425 LYS B C 1 ATOM 6487 O O . LYS B 1 392 ? -61.140 43.143 34.655 1.00 20.13 ? 425 LYS B O 1 ATOM 6488 C CB . LYS B 1 392 ? -61.334 46.163 35.868 1.00 18.90 ? 425 LYS B CB 1 ATOM 6489 C CG . LYS B 1 392 ? -60.212 45.440 36.627 1.00 17.94 ? 425 LYS B CG 1 ATOM 6490 C CD . LYS B 1 392 ? -59.552 46.389 37.623 1.00 16.38 ? 425 LYS B CD 1 ATOM 6491 C CE . LYS B 1 392 ? -58.392 45.709 38.330 1.00 15.76 ? 425 LYS B CE 1 ATOM 6492 N NZ . LYS B 1 392 ? -57.916 46.428 39.543 1.00 15.21 1 425 LYS B NZ 1 ATOM 6493 N N . ALA B 1 393 ? -63.128 43.742 35.370 1.00 19.84 ? 426 ALA B N 1 ATOM 6494 C CA . ALA B 1 393 ? -63.474 42.411 35.666 1.00 21.32 ? 426 ALA B CA 1 ATOM 6495 C C . ALA B 1 393 ? -63.445 41.639 34.346 1.00 21.61 ? 426 ALA B C 1 ATOM 6496 O O . ALA B 1 393 ? -62.865 40.530 34.278 1.00 19.66 ? 426 ALA B O 1 ATOM 6497 C CB . ALA B 1 393 ? -64.834 42.355 36.416 1.00 21.36 ? 426 ALA B CB 1 ATOM 6498 N N . PHE B 1 394 ? -64.023 42.214 33.297 1.00 22.05 ? 427 PHE B N 1 ATOM 6499 C CA . PHE B 1 394 ? -63.931 41.512 32.012 1.00 26.77 ? 427 PHE B CA 1 ATOM 6500 C C . PHE B 1 394 ? -62.453 41.166 31.666 1.00 25.81 ? 427 PHE B C 1 ATOM 6501 O O . PHE B 1 394 ? -62.151 40.027 31.297 1.00 23.69 ? 427 PHE B O 1 ATOM 6502 C CB . PHE B 1 394 ? -64.593 42.300 30.843 1.00 28.40 ? 427 PHE B CB 1 ATOM 6503 C CG . PHE B 1 394 ? -66.098 42.457 30.974 1.00 30.40 ? 427 PHE B CG 1 ATOM 6504 C CD1 . PHE B 1 394 ? -66.842 41.626 31.826 1.00 29.37 ? 427 PHE B CD1 1 ATOM 6505 C CD2 . PHE B 1 394 ? -66.759 43.462 30.253 1.00 30.60 ? 427 PHE B CD2 1 ATOM 6506 C CE1 . PHE B 1 394 ? -68.192 41.798 31.953 1.00 31.00 ? 427 PHE B CE1 1 ATOM 6507 C CE2 . PHE B 1 394 ? -68.110 43.634 30.370 1.00 31.87 ? 427 PHE B CE2 1 ATOM 6508 C CZ . PHE B 1 394 ? -68.836 42.791 31.217 1.00 33.99 ? 427 PHE B CZ 1 ATOM 6509 N N . GLN B 1 395 ? -61.563 42.147 31.833 1.00 22.84 ? 428 GLN B N 1 ATOM 6510 C CA . GLN B 1 395 ? -60.179 41.996 31.445 1.00 23.68 ? 428 GLN B CA 1 ATOM 6511 C C . GLN B 1 395 ? -59.516 40.947 32.316 1.00 22.87 ? 428 GLN B C 1 ATOM 6512 O O . GLN B 1 395 ? -58.961 40.015 31.797 1.00 19.98 ? 428 GLN B O 1 ATOM 6513 C CB . GLN B 1 395 ? -59.399 43.331 31.473 1.00 23.90 ? 428 GLN B CB 1 ATOM 6514 C CG . GLN B 1 395 ? -59.800 44.336 30.401 1.00 26.09 ? 428 GLN B CG 1 ATOM 6515 C CD . GLN B 1 395 ? -59.090 44.199 29.012 1.00 28.17 ? 428 GLN B CD 1 ATOM 6516 O OE1 . GLN B 1 395 ? -57.899 43.921 28.905 1.00 33.13 ? 428 GLN B OE1 1 ATOM 6517 N NE2 . GLN B 1 395 ? -59.810 44.509 27.964 1.00 26.54 ? 428 GLN B NE2 1 ATOM 6518 N N . ILE B 1 396 ? -59.607 41.113 33.627 1.00 24.71 ? 429 ILE B N 1 ATOM 6519 C CA . ILE B 1 396 ? -58.965 40.218 34.615 1.00 27.48 ? 429 ILE B CA 1 ATOM 6520 C C . ILE B 1 396 ? -59.292 38.740 34.335 1.00 26.89 ? 429 ILE B C 1 ATOM 6521 O O . ILE B 1 396 ? -58.385 37.924 34.126 1.00 25.41 ? 429 ILE B O 1 ATOM 6522 C CB . ILE B 1 396 ? -59.363 40.628 36.071 1.00 29.91 ? 429 ILE B CB 1 ATOM 6523 C CG1 . ILE B 1 396 ? -58.752 41.987 36.445 1.00 32.19 ? 429 ILE B CG1 1 ATOM 6524 C CG2 . ILE B 1 396 ? -58.992 39.599 37.142 1.00 31.01 ? 429 ILE B CG2 1 ATOM 6525 C CD1 . ILE B 1 396 ? -57.376 42.222 35.923 1.00 31.40 ? 429 ILE B CD1 1 ATOM 6526 N N . CYS B 1 397 ? -60.581 38.428 34.279 1.00 24.79 ? 430 CYS B N 1 ATOM 6527 C CA . CYS B 1 397 ? -61.022 37.079 34.064 1.00 24.70 ? 430 CYS B CA 1 ATOM 6528 C C . CYS B 1 397 ? -60.703 36.492 32.736 1.00 21.87 ? 430 CYS B C 1 ATOM 6529 O O . CYS B 1 397 ? -60.501 35.304 32.653 1.00 23.05 ? 430 CYS B O 1 ATOM 6530 C CB . CYS B 1 397 ? -62.535 36.979 34.259 1.00 28.15 ? 430 CYS B CB 1 ATOM 6531 S SG . CYS B 1 397 ? -63.037 37.462 35.931 1.00 29.07 ? 430 CYS B SG 1 ATOM 6532 N N . ALA B 1 398 ? -60.718 37.289 31.688 1.00 20.61 ? 431 ALA B N 1 ATOM 6533 C CA . ALA B 1 398 ? -60.301 36.778 30.353 1.00 20.18 ? 431 ALA B CA 1 ATOM 6534 C C . ALA B 1 398 ? -58.816 36.438 30.314 1.00 18.87 ? 431 ALA B C 1 ATOM 6535 O O . ALA B 1 398 ? -58.430 35.477 29.657 1.00 20.17 ? 431 ALA B O 1 ATOM 6536 C CB . ALA B 1 398 ? -60.651 37.756 29.239 1.00 20.07 ? 431 ALA B CB 1 ATOM 6537 N N . ILE B 1 399 ? -58.008 37.207 31.029 1.00 17.91 ? 432 ILE B N 1 ATOM 6538 C CA . ILE B 1 399 ? -56.617 36.877 31.240 1.00 19.28 ? 432 ILE B CA 1 ATOM 6539 C C . ILE B 1 399 ? -56.361 35.494 31.969 1.00 19.92 ? 432 ILE B C 1 ATOM 6540 O O . ILE B 1 399 ? -55.607 34.655 31.506 1.00 17.74 ? 432 ILE B O 1 ATOM 6541 C CB . ILE B 1 399 ? -55.846 38.008 31.985 1.00 19.40 ? 432 ILE B CB 1 ATOM 6542 C CG1 . ILE B 1 399 ? -55.920 39.394 31.260 1.00 18.25 ? 432 ILE B CG1 1 ATOM 6543 C CG2 . ILE B 1 399 ? -54.383 37.575 32.108 1.00 20.38 ? 432 ILE B CG2 1 ATOM 6544 C CD1 . ILE B 1 399 ? -55.320 40.597 31.978 1.00 16.68 ? 432 ILE B CD1 1 ATOM 6545 N N . MET B 1 400 ? -56.996 35.244 33.083 1.00 21.10 ? 433 MET B N 1 ATOM 6546 C CA . MET B 1 400 ? -56.555 34.159 33.888 1.00 25.11 ? 433 MET B CA 1 ATOM 6547 C C . MET B 1 400 ? -57.432 32.936 33.617 1.00 25.49 ? 433 MET B C 1 ATOM 6548 O O . MET B 1 400 ? -57.134 31.814 34.097 1.00 27.73 ? 433 MET B O 1 ATOM 6549 C CB . MET B 1 400 ? -56.656 34.535 35.374 1.00 29.82 ? 433 MET B CB 1 ATOM 6550 C CG . MET B 1 400 ? -55.739 35.640 35.901 1.00 33.75 ? 433 MET B CG 1 ATOM 6551 S SD . MET B 1 400 ? -56.290 36.360 37.518 1.00 39.19 ? 433 MET B SD 1 ATOM 6552 C CE . MET B 1 400 ? -55.630 35.027 38.502 1.00 31.51 ? 433 MET B CE 1 ATOM 6553 N N . ASN B 1 401 ? -58.524 33.122 32.883 1.00 25.04 ? 434 ASN B N 1 ATOM 6554 C CA . ASN B 1 401 ? -59.589 32.080 32.826 1.00 24.41 ? 434 ASN B CA 1 ATOM 6555 C C . ASN B 1 401 ? -60.120 31.823 31.450 1.00 22.63 ? 434 ASN B C 1 ATOM 6556 O O . ASN B 1 401 ? -61.072 32.481 31.016 1.00 23.11 ? 434 ASN B O 1 ATOM 6557 C CB . ASN B 1 401 ? -60.763 32.445 33.742 1.00 25.46 ? 434 ASN B CB 1 ATOM 6558 C CG . ASN B 1 401 ? -60.361 32.520 35.210 1.00 26.17 ? 434 ASN B CG 1 ATOM 6559 O OD1 . ASN B 1 401 ? -60.070 31.471 35.889 1.00 32.12 ? 434 ASN B OD1 1 ATOM 6560 N ND2 . ASN B 1 401 ? -60.310 33.742 35.714 1.00 22.36 ? 434 ASN B ND2 1 ATOM 6561 N N . LEU B 1 402 ? -59.518 30.832 30.823 1.00 22.16 ? 435 LEU B N 1 ATOM 6562 C CA . LEU B 1 402 ? -59.693 30.509 29.444 1.00 25.48 ? 435 LEU B CA 1 ATOM 6563 C C . LEU B 1 402 ? -60.877 29.623 29.121 1.00 28.92 ? 435 LEU B C 1 ATOM 6564 O O . LEU B 1 402 ? -61.445 29.763 28.019 1.00 27.80 ? 435 LEU B O 1 ATOM 6565 C CB . LEU B 1 402 ? -58.440 29.857 28.868 1.00 25.84 ? 435 LEU B CB 1 ATOM 6566 C CG . LEU B 1 402 ? -57.467 30.933 28.482 1.00 27.97 ? 435 LEU B CG 1 ATOM 6567 C CD1 . LEU B 1 402 ? -56.938 31.568 29.729 1.00 29.43 ? 435 LEU B CD1 1 ATOM 6568 C CD2 . LEU B 1 402 ? -56.343 30.314 27.717 1.00 30.91 ? 435 LEU B CD2 1 ATOM 6569 N N . ASP B 1 403 ? -61.261 28.696 30.003 1.00 31.56 ? 436 ASP B N 1 ATOM 6570 C CA . ASP B 1 403 ? -62.361 27.796 29.621 1.00 33.92 ? 436 ASP B CA 1 ATOM 6571 C C . ASP B 1 403 ? -63.572 28.206 30.383 1.00 34.79 ? 436 ASP B C 1 ATOM 6572 O O . ASP B 1 403 ? -63.486 29.084 31.220 1.00 36.53 ? 436 ASP B O 1 ATOM 6573 C CB . ASP B 1 403 ? -61.981 26.320 29.778 1.00 37.80 ? 436 ASP B CB 1 ATOM 6574 C CG . ASP B 1 403 ? -62.181 25.819 31.162 1.00 40.14 ? 436 ASP B CG 1 ATOM 6575 O OD1 . ASP B 1 403 ? -62.201 26.674 32.066 1.00 37.52 ? 436 ASP B OD1 1 ATOM 6576 O OD2 . ASP B 1 403 ? -62.341 24.579 31.331 1.00 47.85 -1 436 ASP B OD2 1 ATOM 6577 N N . ASN B 1 404 ? -64.703 27.595 30.051 1.00 41.24 ? 437 ASN B N 1 ATOM 6578 C CA . ASN B 1 404 ? -66.055 27.949 30.615 1.00 41.73 ? 437 ASN B CA 1 ATOM 6579 C C . ASN B 1 404 ? -66.239 28.036 32.169 1.00 41.03 ? 437 ASN B C 1 ATOM 6580 O O . ASN B 1 404 ? -66.837 29.005 32.668 1.00 38.61 ? 437 ASN B O 1 ATOM 6581 C CB . ASN B 1 404 ? -67.175 27.073 29.984 1.00 40.45 ? 437 ASN B CB 1 ATOM 6582 C CG . ASN B 1 404 ? -66.752 25.608 29.750 1.00 42.31 ? 437 ASN B CG 1 ATOM 6583 O OD1 . ASN B 1 404 ? -67.201 24.983 28.785 1.00 44.20 ? 437 ASN B OD1 1 ATOM 6584 N ND2 . ASN B 1 404 ? -65.878 25.056 30.609 1.00 41.00 ? 437 ASN B ND2 1 ATOM 6585 N N . ILE B 1 405 ? -65.698 27.092 32.934 1.00 41.57 ? 438 ILE B N 1 ATOM 6586 C CA . ILE B 1 405 ? -66.055 26.999 34.360 1.00 47.67 ? 438 ILE B CA 1 ATOM 6587 C C . ILE B 1 405 ? -65.386 28.149 35.134 1.00 47.62 ? 438 ILE B C 1 ATOM 6588 O O . ILE B 1 405 ? -66.052 28.940 35.837 1.00 47.14 ? 438 ILE B O 1 ATOM 6589 C CB . ILE B 1 405 ? -65.679 25.632 35.015 1.00 48.67 ? 438 ILE B CB 1 ATOM 6590 C CG1 . ILE B 1 405 ? -66.175 24.421 34.182 1.00 50.21 ? 438 ILE B CG1 1 ATOM 6591 C CG2 . ILE B 1 405 ? -66.238 25.573 36.442 1.00 49.61 ? 438 ILE B CG2 1 ATOM 6592 C CD1 . ILE B 1 405 ? -67.630 24.015 34.397 1.00 48.23 ? 438 ILE B CD1 1 ATOM 6593 N N . SER B 1 406 ? -64.061 28.189 35.005 1.00 43.32 ? 439 SER B N 1 ATOM 6594 C CA . SER B 1 406 ? -63.208 29.290 35.482 1.00 40.57 ? 439 SER B CA 1 ATOM 6595 C C . SER B 1 406 ? -63.719 30.697 35.120 1.00 37.16 ? 439 SER B C 1 ATOM 6596 O O . SER B 1 406 ? -63.683 31.603 35.935 1.00 34.40 ? 439 SER B O 1 ATOM 6597 C CB . SER B 1 406 ? -61.808 29.119 34.881 1.00 36.37 ? 439 SER B CB 1 ATOM 6598 O OG . SER B 1 406 ? -61.111 28.181 35.643 1.00 40.16 ? 439 SER B OG 1 ATOM 6599 N N . TYR B 1 407 ? -64.156 30.875 33.877 1.00 33.45 ? 440 TYR B N 1 ATOM 6600 C CA . TYR B 1 407 ? -64.505 32.189 33.427 1.00 31.19 ? 440 TYR B CA 1 ATOM 6601 C C . TYR B 1 407 ? -65.681 32.690 34.231 1.00 29.97 ? 440 TYR B C 1 ATOM 6602 O O . TYR B 1 407 ? -65.624 33.784 34.753 1.00 27.91 ? 440 TYR B O 1 ATOM 6603 C CB . TYR B 1 407 ? -64.764 32.229 31.920 1.00 30.78 ? 440 TYR B CB 1 ATOM 6604 C CG . TYR B 1 407 ? -65.050 33.635 31.479 1.00 30.22 ? 440 TYR B CG 1 ATOM 6605 C CD1 . TYR B 1 407 ? -64.020 34.603 31.453 1.00 29.53 ? 440 TYR B CD1 1 ATOM 6606 C CD2 . TYR B 1 407 ? -66.356 34.029 31.159 1.00 27.84 ? 440 TYR B CD2 1 ATOM 6607 C CE1 . TYR B 1 407 ? -64.297 35.916 31.084 1.00 27.46 ? 440 TYR B CE1 1 ATOM 6608 C CE2 . TYR B 1 407 ? -66.642 35.317 30.812 1.00 25.51 ? 440 TYR B CE2 1 ATOM 6609 C CZ . TYR B 1 407 ? -65.622 36.249 30.771 1.00 26.31 ? 440 TYR B CZ 1 ATOM 6610 O OH . TYR B 1 407 ? -65.915 37.520 30.378 1.00 27.18 ? 440 TYR B OH 1 ATOM 6611 N N . ALA B 1 408 ? -66.718 31.867 34.366 1.00 33.62 ? 441 ALA B N 1 ATOM 6612 C CA . ALA B 1 408 ? -67.851 32.134 35.314 1.00 37.68 ? 441 ALA B CA 1 ATOM 6613 C C . ALA B 1 408 ? -67.409 32.247 36.798 1.00 38.37 ? 441 ALA B C 1 ATOM 6614 O O . ALA B 1 408 ? -67.590 33.278 37.432 1.00 41.22 ? 441 ALA B O 1 ATOM 6615 C CB . ALA B 1 408 ? -68.949 31.081 35.163 1.00 37.61 ? 441 ALA B CB 1 ATOM 6616 N N . ASP B 1 409 ? -66.776 31.214 37.334 1.00 41.11 ? 442 ASP B N 1 ATOM 6617 C CA . ASP B 1 409 ? -66.302 31.244 38.735 1.00 43.02 ? 442 ASP B CA 1 ATOM 6618 C C . ASP B 1 409 ? -65.558 32.548 39.124 1.00 36.60 ? 442 ASP B C 1 ATOM 6619 O O . ASP B 1 409 ? -65.482 32.897 40.335 1.00 33.73 ? 442 ASP B O 1 ATOM 6620 C CB . ASP B 1 409 ? -65.457 30.000 39.034 1.00 46.57 ? 442 ASP B CB 1 ATOM 6621 C CG . ASP B 1 409 ? -64.929 29.983 40.460 1.00 52.97 ? 442 ASP B CG 1 ATOM 6622 O OD1 . ASP B 1 409 ? -65.427 29.166 41.281 1.00 55.45 ? 442 ASP B OD1 1 ATOM 6623 O OD2 . ASP B 1 409 ? -64.021 30.799 40.760 1.00 53.08 -1 442 ASP B OD2 1 ATOM 6624 N N . CYS B 1 410 ? -65.022 33.214 38.096 1.00 29.95 ? 443 CYS B N 1 ATOM 6625 C CA . CYS B 1 410 ? -64.541 34.619 38.111 1.00 29.92 ? 443 CYS B CA 1 ATOM 6626 C C . CYS B 1 410 ? -65.726 35.424 37.556 1.00 30.05 ? 443 CYS B C 1 ATOM 6627 O O . CYS B 1 410 ? -65.871 36.622 37.761 1.00 27.88 ? 443 CYS B O 1 ATOM 6628 C CB . CYS B 1 410 ? -63.301 34.716 37.172 1.00 29.99 ? 443 CYS B CB 1 ATOM 6629 S SG . CYS B 1 410 ? -62.117 36.125 37.156 1.00 29.91 ? 443 CYS B SG 1 ATOM 6630 N N . PRO C 1 1 ? -30.917 50.291 34.159 1.00 48.35 ? 34 PRO C N 1 ATOM 6631 C CA . PRO C 1 1 ? -31.696 50.452 32.921 1.00 48.78 ? 34 PRO C CA 1 ATOM 6632 C C . PRO C 1 1 ? -31.584 49.252 31.961 1.00 44.56 ? 34 PRO C C 1 ATOM 6633 O O . PRO C 1 1 ? -30.501 48.724 31.782 1.00 48.04 ? 34 PRO C O 1 ATOM 6634 C CB . PRO C 1 1 ? -31.050 51.690 32.272 1.00 48.88 ? 34 PRO C CB 1 ATOM 6635 C CG . PRO C 1 1 ? -29.621 51.594 32.684 1.00 48.39 ? 34 PRO C CG 1 ATOM 6636 C CD . PRO C 1 1 ? -29.603 50.948 34.054 1.00 48.98 ? 34 PRO C CD 1 ATOM 6637 N N . PRO C 1 2 ? -32.681 48.883 31.288 1.00 43.51 ? 35 PRO C N 1 ATOM 6638 C CA . PRO C 1 2 ? -32.798 47.681 30.439 1.00 43.28 ? 35 PRO C CA 1 ATOM 6639 C C . PRO C 1 2 ? -31.891 47.575 29.227 1.00 36.40 ? 35 PRO C C 1 ATOM 6640 O O . PRO C 1 2 ? -31.491 46.484 28.890 1.00 33.69 ? 35 PRO C O 1 ATOM 6641 C CB . PRO C 1 2 ? -34.223 47.756 29.911 1.00 46.61 ? 35 PRO C CB 1 ATOM 6642 C CG . PRO C 1 2 ? -34.633 49.176 30.040 1.00 47.80 ? 35 PRO C CG 1 ATOM 6643 C CD . PRO C 1 2 ? -33.871 49.746 31.190 1.00 48.86 ? 35 PRO C CD 1 ATOM 6644 N N . ALA C 1 3 ? -31.666 48.690 28.549 1.00 33.37 ? 36 ALA C N 1 ATOM 6645 C CA . ALA C 1 3 ? -30.693 48.785 27.459 1.00 32.82 ? 36 ALA C CA 1 ATOM 6646 C C . ALA C 1 3 ? -29.820 49.973 27.757 1.00 31.67 ? 36 ALA C C 1 ATOM 6647 O O . ALA C 1 3 ? -30.222 50.876 28.472 1.00 30.28 ? 36 ALA C O 1 ATOM 6648 C CB . ALA C 1 3 ? -31.366 48.943 26.078 1.00 31.63 ? 36 ALA C CB 1 ATOM 6649 N N . ILE C 1 4 ? -28.604 49.924 27.219 1.00 33.62 ? 37 ILE C N 1 ATOM 6650 C CA . ILE C 1 4 ? -27.629 51.021 27.250 1.00 31.96 ? 37 ILE C CA 1 ATOM 6651 C C . ILE C 1 4 ? -27.513 51.639 25.842 1.00 29.11 ? 37 ILE C C 1 ATOM 6652 O O . ILE C 1 4 ? -27.246 50.940 24.876 1.00 29.74 ? 37 ILE C O 1 ATOM 6653 C CB . ILE C 1 4 ? -26.223 50.512 27.643 1.00 32.71 ? 37 ILE C CB 1 ATOM 6654 C CG1 . ILE C 1 4 ? -26.251 49.780 29.012 1.00 34.76 ? 37 ILE C CG1 1 ATOM 6655 C CG2 . ILE C 1 4 ? -25.214 51.662 27.670 1.00 33.23 ? 37 ILE C CG2 1 ATOM 6656 C CD1 . ILE C 1 4 ? -26.440 50.659 30.240 1.00 33.76 ? 37 ILE C CD1 1 ATOM 6657 N N . GLY C 1 5 ? -27.695 52.947 25.730 1.00 25.81 ? 38 GLY C N 1 ATOM 6658 C CA . GLY C 1 5 ? -27.407 53.684 24.486 1.00 22.93 ? 38 GLY C CA 1 ATOM 6659 C C . GLY C 1 5 ? -25.962 54.163 24.406 1.00 20.96 ? 38 GLY C C 1 ATOM 6660 O O . GLY C 1 5 ? -25.359 54.511 25.425 1.00 19.38 ? 38 GLY C O 1 ATOM 6661 N N . GLN C 1 6 ? -25.409 54.145 23.186 1.00 20.13 ? 39 GLN C N 1 ATOM 6662 C CA . GLN C 1 6 ? -24.041 54.647 22.902 1.00 19.70 ? 39 GLN C CA 1 ATOM 6663 C C . GLN C 1 6 ? -23.918 55.596 21.726 1.00 19.13 ? 39 GLN C C 1 ATOM 6664 O O . GLN C 1 6 ? -24.526 55.425 20.685 1.00 22.68 ? 39 GLN C O 1 ATOM 6665 C CB . GLN C 1 6 ? -23.065 53.489 22.718 1.00 20.05 ? 39 GLN C CB 1 ATOM 6666 C CG . GLN C 1 6 ? -23.110 52.548 23.922 1.00 20.66 ? 39 GLN C CG 1 ATOM 6667 C CD . GLN C 1 6 ? -21.986 51.575 23.959 1.00 20.74 ? 39 GLN C CD 1 ATOM 6668 O OE1 . GLN C 1 6 ? -21.493 51.151 22.920 1.00 22.71 ? 39 GLN C OE1 1 ATOM 6669 N NE2 . GLN C 1 6 ? -21.573 51.216 25.151 1.00 20.31 ? 39 GLN C NE2 1 ATOM 6670 N N . PHE C 1 7 ? -23.141 56.624 21.905 1.00 17.74 ? 40 PHE C N 1 ATOM 6671 C CA . PHE C 1 7 ? -22.687 57.348 20.767 1.00 17.01 ? 40 PHE C CA 1 ATOM 6672 C C . PHE C 1 7 ? -21.214 57.667 20.823 1.00 15.60 ? 40 PHE C C 1 ATOM 6673 O O . PHE C 1 7 ? -20.581 57.860 21.934 1.00 12.34 ? 40 PHE C O 1 ATOM 6674 C CB . PHE C 1 7 ? -23.500 58.643 20.594 1.00 18.12 ? 40 PHE C CB 1 ATOM 6675 C CG . PHE C 1 7 ? -23.492 59.616 21.776 1.00 17.86 ? 40 PHE C CG 1 ATOM 6676 C CD1 . PHE C 1 7 ? -24.315 59.428 22.863 1.00 19.59 ? 40 PHE C CD1 1 ATOM 6677 C CD2 . PHE C 1 7 ? -22.736 60.759 21.742 1.00 18.47 ? 40 PHE C CD2 1 ATOM 6678 C CE1 . PHE C 1 7 ? -24.385 60.354 23.916 1.00 19.06 ? 40 PHE C CE1 1 ATOM 6679 C CE2 . PHE C 1 7 ? -22.787 61.684 22.773 1.00 19.69 ? 40 PHE C CE2 1 ATOM 6680 C CZ . PHE C 1 7 ? -23.613 61.484 23.863 1.00 18.79 ? 40 PHE C CZ 1 ATOM 6681 N N . TRP C 1 8 ? -20.703 57.796 19.599 1.00 15.37 ? 41 TRP C N 1 ATOM 6682 C CA . TRP C 1 8 ? -19.325 58.214 19.420 1.00 15.26 ? 41 TRP C CA 1 ATOM 6683 C C . TRP C 1 8 ? -19.297 59.782 19.380 1.00 15.12 ? 41 TRP C C 1 ATOM 6684 O O . TRP C 1 8 ? -20.286 60.456 18.959 1.00 13.63 ? 41 TRP C O 1 ATOM 6685 C CB . TRP C 1 8 ? -18.721 57.576 18.175 1.00 14.71 ? 41 TRP C CB 1 ATOM 6686 C CG . TRP C 1 8 ? -18.499 56.162 18.234 1.00 15.75 ? 41 TRP C CG 1 ATOM 6687 C CD1 . TRP C 1 8 ? -19.227 55.191 17.588 1.00 17.28 ? 41 TRP C CD1 1 ATOM 6688 C CD2 . TRP C 1 8 ? -17.442 55.459 18.930 1.00 17.22 ? 41 TRP C CD2 1 ATOM 6689 N NE1 . TRP C 1 8 ? -18.697 53.933 17.836 1.00 16.96 ? 41 TRP C NE1 1 ATOM 6690 C CE2 . TRP C 1 8 ? -17.584 54.075 18.623 1.00 16.89 ? 41 TRP C CE2 1 ATOM 6691 C CE3 . TRP C 1 8 ? -16.354 55.863 19.730 1.00 16.84 ? 41 TRP C CE3 1 ATOM 6692 C CZ2 . TRP C 1 8 ? -16.731 53.120 19.131 1.00 16.57 ? 41 TRP C CZ2 1 ATOM 6693 C CZ3 . TRP C 1 8 ? -15.514 54.916 20.198 1.00 16.75 ? 41 TRP C CZ3 1 ATOM 6694 C CH2 . TRP C 1 8 ? -15.720 53.547 19.930 1.00 16.32 ? 41 TRP C CH2 1 ATOM 6695 N N . HIS C 1 9 ? -18.179 60.323 19.873 1.00 14.97 ? 42 HIS C N 1 ATOM 6696 C CA . HIS C 1 9 ? -17.791 61.760 19.714 1.00 14.73 ? 42 HIS C CA 1 ATOM 6697 C C . HIS C 1 9 ? -16.323 61.709 19.237 1.00 13.19 ? 42 HIS C C 1 ATOM 6698 O O . HIS C 1 9 ? -15.447 61.224 19.985 1.00 13.70 ? 42 HIS C O 1 ATOM 6699 C CB . HIS C 1 9 ? -17.838 62.502 21.041 1.00 15.71 ? 42 HIS C CB 1 ATOM 6700 C CG . HIS C 1 9 ? -17.559 63.985 20.967 1.00 17.89 ? 42 HIS C CG 1 ATOM 6701 N ND1 . HIS C 1 9 ? -17.749 64.824 22.057 1.00 17.57 ? 42 HIS C ND1 1 ATOM 6702 C CD2 . HIS C 1 9 ? -17.185 64.789 19.935 1.00 18.56 ? 42 HIS C CD2 1 ATOM 6703 C CE1 . HIS C 1 9 ? -17.489 66.068 21.704 1.00 18.08 ? 42 HIS C CE1 1 ATOM 6704 N NE2 . HIS C 1 9 ? -17.164 66.078 20.424 1.00 20.21 ? 42 HIS C NE2 1 ATOM 6705 N N . VAL C 1 10 ? -16.136 62.119 17.982 1.00 10.91 ? 43 VAL C N 1 ATOM 6706 C CA . VAL C 1 10 ? -14.907 62.416 17.366 1.00 10.37 ? 43 VAL C CA 1 ATOM 6707 C C . VAL C 1 10 ? -14.834 63.947 16.915 1.00 9.93 ? 43 VAL C C 1 ATOM 6708 O O . VAL C 1 10 ? -15.876 64.552 16.621 1.00 10.65 ? 43 VAL C O 1 ATOM 6709 C CB . VAL C 1 10 ? -14.786 61.560 16.114 1.00 11.03 ? 43 VAL C CB 1 ATOM 6710 C CG1 . VAL C 1 10 ? -14.839 60.040 16.428 1.00 11.27 ? 43 VAL C CG1 1 ATOM 6711 C CG2 . VAL C 1 10 ? -15.805 62.007 15.059 1.00 11.29 ? 43 VAL C CG2 1 ATOM 6712 N N . THR C 1 11 ? -13.623 64.531 16.846 1.00 8.38 ? 44 THR C N 1 ATOM 6713 C CA . THR C 1 11 ? -13.386 65.953 16.786 1.00 7.60 ? 44 THR C CA 1 ATOM 6714 C C . THR C 1 11 ? -11.956 66.245 16.388 1.00 7.99 ? 44 THR C C 1 ATOM 6715 O O . THR C 1 11 ? -11.016 65.472 16.623 1.00 7.59 ? 44 THR C O 1 ATOM 6716 C CB . THR C 1 11 ? -13.767 66.675 18.102 1.00 7.00 ? 44 THR C CB 1 ATOM 6717 O OG1 . THR C 1 11 ? -13.966 68.053 17.860 1.00 6.94 ? 44 THR C OG1 1 ATOM 6718 C CG2 . THR C 1 11 ? -12.779 66.496 19.198 1.00 6.72 ? 44 THR C CG2 1 ATOM 6719 N N . ASP C 1 12 ? -11.824 67.341 15.668 1.00 8.97 ? 45 ASP C N 1 ATOM 6720 C CA . ASP C 1 12 ? -10.531 67.869 15.334 1.00 10.91 ? 45 ASP C CA 1 ATOM 6721 C C . ASP C 1 12 ? -9.606 66.785 14.574 1.00 11.42 ? 45 ASP C C 1 ATOM 6722 O O . ASP C 1 12 ? -8.482 66.499 14.932 1.00 11.14 ? 45 ASP C O 1 ATOM 6723 C CB . ASP C 1 12 ? -9.921 68.491 16.647 1.00 12.11 ? 45 ASP C CB 1 ATOM 6724 C CG . ASP C 1 12 ? -10.758 69.719 17.197 1.00 12.58 ? 45 ASP C CG 1 ATOM 6725 O OD1 . ASP C 1 12 ? -10.393 70.894 16.847 1.00 14.68 ? 45 ASP C OD1 1 ATOM 6726 O OD2 . ASP C 1 12 ? -11.774 69.532 17.954 1.00 12.07 -1 45 ASP C OD2 1 ATOM 6727 N N . LEU C 1 13 ? -10.175 66.198 13.527 1.00 11.71 ? 46 LEU C N 1 ATOM 6728 C CA . LEU C 1 13 ? -9.502 65.348 12.605 1.00 11.68 ? 46 LEU C CA 1 ATOM 6729 C C . LEU C 1 13 ? -8.285 65.996 11.981 1.00 11.02 ? 46 LEU C C 1 ATOM 6730 O O . LEU C 1 13 ? -7.316 65.381 11.905 1.00 11.11 ? 46 LEU C O 1 ATOM 6731 C CB . LEU C 1 13 ? -10.504 64.969 11.473 1.00 12.37 ? 46 LEU C CB 1 ATOM 6732 C CG . LEU C 1 13 ? -11.721 64.080 11.907 1.00 12.16 ? 46 LEU C CG 1 ATOM 6733 C CD1 . LEU C 1 13 ? -12.563 63.612 10.742 1.00 12.39 ? 46 LEU C CD1 1 ATOM 6734 C CD2 . LEU C 1 13 ? -11.300 62.859 12.619 1.00 12.08 ? 46 LEU C CD2 1 ATOM 6735 N N . HIS C 1 14 ? -8.372 67.245 11.552 1.00 11.24 ? 47 HIS C N 1 ATOM 6736 C CA . HIS C 1 14 ? -7.316 68.026 10.887 1.00 11.81 ? 47 HIS C CA 1 ATOM 6737 C C . HIS C 1 14 ? -6.444 67.269 9.908 1.00 13.01 ? 47 HIS C C 1 ATOM 6738 O O . HIS C 1 14 ? -5.201 67.040 10.114 1.00 11.72 ? 47 HIS C O 1 ATOM 6739 C CB . HIS C 1 14 ? -6.380 68.715 11.860 1.00 12.34 ? 47 HIS C CB 1 ATOM 6740 C CG . HIS C 1 14 ? -7.012 69.751 12.649 1.00 11.66 ? 47 HIS C CG 1 ATOM 6741 N ND1 . HIS C 1 14 ? -7.501 70.885 12.062 1.00 11.20 ? 47 HIS C ND1 1 ATOM 6742 C CD2 . HIS C 1 14 ? -7.293 69.821 13.979 1.00 12.48 ? 47 HIS C CD2 1 ATOM 6743 C CE1 . HIS C 1 14 ? -8.024 71.654 13.012 1.00 12.07 ? 47 HIS C CE1 1 ATOM 6744 N NE2 . HIS C 1 14 ? -7.918 71.024 14.187 1.00 12.26 ? 47 HIS C NE2 1 ATOM 6745 N N . LEU C 1 15 ? -7.071 66.909 8.822 1.00 13.46 ? 48 LEU C N 1 ATOM 6746 C CA . LEU C 1 15 ? -6.321 66.199 7.886 1.00 13.33 ? 48 LEU C CA 1 ATOM 6747 C C . LEU C 1 15 ? -5.274 67.078 7.241 1.00 13.60 ? 48 LEU C C 1 ATOM 6748 O O . LEU C 1 15 ? -5.606 68.119 6.730 1.00 13.90 ? 48 LEU C O 1 ATOM 6749 C CB . LEU C 1 15 ? -7.296 65.700 6.838 1.00 12.55 ? 48 LEU C CB 1 ATOM 6750 C CG . LEU C 1 15 ? -6.697 65.331 5.506 1.00 11.41 ? 48 LEU C CG 1 ATOM 6751 C CD1 . LEU C 1 15 ? -5.824 64.079 5.488 1.00 10.91 ? 48 LEU C CD1 1 ATOM 6752 C CD2 . LEU C 1 15 ? -7.876 65.282 4.606 1.00 11.61 ? 48 LEU C CD2 1 ATOM 6753 N N . ASP C 1 16 ? -4.034 66.634 7.242 1.00 14.00 ? 49 ASP C N 1 ATOM 6754 C CA . ASP C 1 16 ? -3.053 67.181 6.312 1.00 16.55 ? 49 ASP C CA 1 ATOM 6755 C C . ASP C 1 16 ? -2.932 66.372 4.936 1.00 17.90 ? 49 ASP C C 1 ATOM 6756 O O . ASP C 1 16 ? -2.207 65.377 4.873 1.00 13.32 ? 49 ASP C O 1 ATOM 6757 C CB . ASP C 1 16 ? -1.707 67.281 7.020 1.00 18.57 ? 49 ASP C CB 1 ATOM 6758 C CG . ASP C 1 16 ? -0.692 68.180 6.260 1.00 19.85 ? 49 ASP C CG 1 ATOM 6759 O OD1 . ASP C 1 16 ? -0.718 68.039 5.025 1.00 18.19 ? 49 ASP C OD1 1 ATOM 6760 O OD2 . ASP C 1 16 ? 0.037 69.037 6.926 1.00 20.60 -1 49 ASP C OD2 1 ATOM 6761 N N . PRO C 1 17 ? -3.593 66.865 3.816 1.00 22.60 ? 50 PRO C N 1 ATOM 6762 C CA . PRO C 1 17 ? -3.495 66.144 2.505 1.00 27.28 ? 50 PRO C CA 1 ATOM 6763 C C . PRO C 1 17 ? -2.108 66.201 1.898 1.00 27.55 ? 50 PRO C C 1 ATOM 6764 O O . PRO C 1 17 ? -1.960 65.881 0.761 1.00 34.57 ? 50 PRO C O 1 ATOM 6765 C CB . PRO C 1 17 ? -4.503 66.906 1.582 1.00 26.39 ? 50 PRO C CB 1 ATOM 6766 C CG . PRO C 1 17 ? -5.466 67.490 2.578 1.00 25.98 ? 50 PRO C CG 1 ATOM 6767 C CD . PRO C 1 17 ? -4.537 67.984 3.674 1.00 22.72 ? 50 PRO C CD 1 ATOM 6768 N N . THR C 1 18 ? -1.117 66.606 2.668 1.00 25.40 ? 51 THR C N 1 ATOM 6769 C CA . THR C 1 18 ? 0.186 66.974 2.186 1.00 22.32 ? 51 THR C CA 1 ATOM 6770 C C . THR C 1 18 ? 1.162 65.965 2.840 1.00 23.58 ? 51 THR C C 1 ATOM 6771 O O . THR C 1 18 ? 2.381 65.880 2.498 1.00 22.67 ? 51 THR C O 1 ATOM 6772 C CB . THR C 1 18 ? 0.403 68.466 2.635 1.00 21.50 ? 51 THR C CB 1 ATOM 6773 O OG1 . THR C 1 18 ? 0.519 69.367 1.541 1.00 19.57 ? 51 THR C OG1 1 ATOM 6774 C CG2 . THR C 1 18 ? 1.528 68.621 3.450 1.00 20.22 ? 51 THR C CG2 1 ATOM 6775 N N . TYR C 1 19 ? 0.642 65.146 3.768 1.00 22.58 ? 52 TYR C N 1 ATOM 6776 C CA . TYR C 1 19 ? 1.560 64.245 4.492 1.00 20.88 ? 52 TYR C CA 1 ATOM 6777 C C . TYR C 1 19 ? 2.138 63.098 3.609 1.00 21.03 ? 52 TYR C C 1 ATOM 6778 O O . TYR C 1 19 ? 1.396 62.438 2.900 1.00 21.59 ? 52 TYR C O 1 ATOM 6779 C CB . TYR C 1 19 ? 0.888 63.698 5.728 1.00 18.21 ? 52 TYR C CB 1 ATOM 6780 C CG . TYR C 1 19 ? 1.837 63.127 6.725 1.00 17.10 ? 52 TYR C CG 1 ATOM 6781 C CD1 . TYR C 1 19 ? 2.264 61.817 6.600 1.00 16.77 ? 52 TYR C CD1 1 ATOM 6782 C CD2 . TYR C 1 19 ? 2.322 63.897 7.788 1.00 16.61 ? 52 TYR C CD2 1 ATOM 6783 C CE1 . TYR C 1 19 ? 3.126 61.263 7.500 1.00 16.71 ? 52 TYR C CE1 1 ATOM 6784 C CE2 . TYR C 1 19 ? 3.187 63.345 8.719 1.00 17.01 ? 52 TYR C CE2 1 ATOM 6785 C CZ . TYR C 1 19 ? 3.563 61.994 8.595 1.00 17.18 ? 52 TYR C CZ 1 ATOM 6786 O OH . TYR C 1 19 ? 4.456 61.356 9.513 1.00 16.46 ? 52 TYR C OH 1 ATOM 6787 N N . HIS C 1 20 ? 3.459 62.911 3.665 1.00 20.27 ? 53 HIS C N 1 ATOM 6788 C CA . HIS C 1 20 ? 4.141 61.799 3.042 1.00 19.36 ? 53 HIS C CA 1 ATOM 6789 C C . HIS C 1 20 ? 5.549 61.644 3.701 1.00 21.10 ? 53 HIS C C 1 ATOM 6790 O O . HIS C 1 20 ? 6.295 62.621 3.876 1.00 20.24 ? 53 HIS C O 1 ATOM 6791 C CB . HIS C 1 20 ? 4.201 62.054 1.544 1.00 21.12 ? 53 HIS C CB 1 ATOM 6792 C CG . HIS C 1 20 ? 5.192 63.121 1.122 1.00 21.92 ? 53 HIS C CG 1 ATOM 6793 N ND1 . HIS C 1 20 ? 5.045 64.460 1.428 1.00 23.18 ? 53 HIS C ND1 1 ATOM 6794 C CD2 . HIS C 1 20 ? 6.320 63.044 0.380 1.00 22.61 ? 53 HIS C CD2 1 ATOM 6795 C CE1 . HIS C 1 20 ? 6.033 65.162 0.894 1.00 22.46 ? 53 HIS C CE1 1 ATOM 6796 N NE2 . HIS C 1 20 ? 6.824 64.329 0.253 1.00 23.85 ? 53 HIS C NE2 1 ATOM 6797 N N . ILE C 1 21 ? 5.911 60.441 4.118 1.00 22.04 ? 54 ILE C N 1 ATOM 6798 C CA . ILE C 1 21 ? 7.265 60.212 4.575 1.00 24.40 ? 54 ILE C CA 1 ATOM 6799 C C . ILE C 1 21 ? 8.304 60.586 3.522 1.00 27.54 ? 54 ILE C C 1 ATOM 6800 O O . ILE C 1 21 ? 8.262 60.019 2.432 1.00 31.20 ? 54 ILE C O 1 ATOM 6801 C CB . ILE C 1 21 ? 7.436 58.722 4.839 1.00 26.29 ? 54 ILE C CB 1 ATOM 6802 C CG1 . ILE C 1 21 ? 6.619 58.292 6.079 1.00 28.37 ? 54 ILE C CG1 1 ATOM 6803 C CG2 . ILE C 1 21 ? 8.913 58.388 5.024 1.00 27.64 ? 54 ILE C CG2 1 ATOM 6804 C CD1 . ILE C 1 21 ? 6.916 59.077 7.366 1.00 27.58 ? 54 ILE C CD1 1 ATOM 6805 N N . THR C 1 22 ? 9.230 61.507 3.795 1.00 27.83 ? 55 THR C N 1 ATOM 6806 C CA . THR C 1 22 ? 10.420 61.629 2.933 1.00 30.70 ? 55 THR C CA 1 ATOM 6807 C C . THR C 1 22 ? 11.694 61.942 3.695 1.00 33.59 ? 55 THR C C 1 ATOM 6808 O O . THR C 1 22 ? 11.641 62.179 4.892 1.00 34.40 ? 55 THR C O 1 ATOM 6809 C CB . THR C 1 22 ? 10.308 62.703 1.832 1.00 33.63 ? 55 THR C CB 1 ATOM 6810 O OG1 . THR C 1 22 ? 11.650 63.082 1.393 1.00 34.98 ? 55 THR C OG1 1 ATOM 6811 C CG2 . THR C 1 22 ? 9.585 63.945 2.359 1.00 33.60 ? 55 THR C CG2 1 ATOM 6812 N N . ASP C 1 23 ? 12.835 61.984 2.991 1.00 37.16 ? 56 ASP C N 1 ATOM 6813 C CA . ASP C 1 23 ? 14.131 62.181 3.667 1.00 43.86 ? 56 ASP C CA 1 ATOM 6814 C C . ASP C 1 23 ? 14.247 63.577 4.255 1.00 41.06 ? 56 ASP C C 1 ATOM 6815 O O . ASP C 1 23 ? 14.879 63.745 5.293 1.00 43.28 ? 56 ASP C O 1 ATOM 6816 C CB . ASP C 1 23 ? 15.341 61.926 2.744 1.00 48.89 ? 56 ASP C CB 1 ATOM 6817 C CG . ASP C 1 23 ? 15.514 60.466 2.404 1.00 53.79 ? 56 ASP C CG 1 ATOM 6818 O OD1 . ASP C 1 23 ? 15.334 59.603 3.302 1.00 53.39 ? 56 ASP C OD1 1 ATOM 6819 O OD2 . ASP C 1 23 ? 15.828 60.194 1.225 1.00 58.66 -1 56 ASP C OD2 1 ATOM 6820 N N . ASP C 1 24 ? 13.654 64.569 3.584 1.00 36.50 ? 57 ASP C N 1 ATOM 6821 C CA . ASP C 1 24 ? 13.682 65.960 4.073 1.00 30.93 ? 57 ASP C CA 1 ATOM 6822 C C . ASP C 1 24 ? 12.494 66.074 5.032 1.00 27.97 ? 57 ASP C C 1 ATOM 6823 O O . ASP C 1 24 ? 11.338 66.164 4.616 1.00 26.28 ? 57 ASP C O 1 ATOM 6824 C CB . ASP C 1 24 ? 13.598 66.975 2.901 1.00 26.75 ? 57 ASP C CB 1 ATOM 6825 C CG . ASP C 1 24 ? 13.855 68.417 3.326 1.00 23.48 ? 57 ASP C CG 1 ATOM 6826 O OD1 . ASP C 1 24 ? 13.467 68.859 4.429 1.00 21.65 ? 57 ASP C OD1 1 ATOM 6827 O OD2 . ASP C 1 24 ? 14.437 69.131 2.524 1.00 20.76 -1 57 ASP C OD2 1 ATOM 6828 N N . HIS C 1 25 ? 12.783 66.042 6.322 1.00 26.03 ? 58 HIS C N 1 ATOM 6829 C CA . HIS C 1 25 ? 11.720 66.158 7.332 1.00 26.22 ? 58 HIS C CA 1 ATOM 6830 C C . HIS C 1 25 ? 11.075 67.528 7.357 1.00 23.20 ? 58 HIS C C 1 ATOM 6831 O O . HIS C 1 25 ? 9.957 67.666 7.847 1.00 22.66 ? 58 HIS C O 1 ATOM 6832 C CB . HIS C 1 25 ? 12.256 65.810 8.729 1.00 28.47 ? 58 HIS C CB 1 ATOM 6833 C CG . HIS C 1 25 ? 12.513 64.352 8.930 1.00 28.62 ? 58 HIS C CG 1 ATOM 6834 N ND1 . HIS C 1 25 ? 12.162 63.389 7.996 1.00 28.80 ? 58 HIS C ND1 1 ATOM 6835 C CD2 . HIS C 1 25 ? 13.048 63.692 9.980 1.00 28.22 ? 58 HIS C CD2 1 ATOM 6836 C CE1 . HIS C 1 25 ? 12.512 62.203 8.452 1.00 29.33 ? 58 HIS C CE1 1 ATOM 6837 N NE2 . HIS C 1 25 ? 13.025 62.357 9.663 1.00 28.54 ? 58 HIS C NE2 1 ATOM 6838 N N . THR C 1 26 ? 11.749 68.536 6.821 1.00 20.46 ? 59 THR C N 1 ATOM 6839 C CA . THR C 1 26 ? 11.037 69.765 6.569 1.00 21.52 ? 59 THR C CA 1 ATOM 6840 C C . THR C 1 26 ? 10.047 69.567 5.461 1.00 22.55 ? 59 THR C C 1 ATOM 6841 O O . THR C 1 26 ? 9.216 70.441 5.276 1.00 25.12 ? 59 THR C O 1 ATOM 6842 C CB . THR C 1 26 ? 11.877 71.021 6.153 1.00 20.43 ? 59 THR C CB 1 ATOM 6843 O OG1 . THR C 1 26 ? 12.258 70.877 4.782 1.00 19.69 ? 59 THR C OG1 1 ATOM 6844 C CG2 . THR C 1 26 ? 13.068 71.292 7.089 1.00 18.68 ? 59 THR C CG2 1 ATOM 6845 N N . LYS C 1 27 ? 10.116 68.490 4.702 1.00 22.61 ? 60 LYS C N 1 ATOM 6846 C CA . LYS C 1 27 ? 9.131 68.309 3.610 1.00 25.39 ? 60 LYS C CA 1 ATOM 6847 C C . LYS C 1 27 ? 8.002 67.279 3.919 1.00 22.80 ? 60 LYS C C 1 ATOM 6848 O O . LYS C 1 27 ? 7.198 66.958 3.060 1.00 21.86 ? 60 LYS C O 1 ATOM 6849 C CB . LYS C 1 27 ? 9.836 67.972 2.240 1.00 27.59 ? 60 LYS C CB 1 ATOM 6850 C CG . LYS C 1 27 ? 10.863 69.006 1.767 1.00 31.83 ? 60 LYS C CG 1 ATOM 6851 C CD . LYS C 1 27 ? 10.448 69.785 0.514 1.00 35.29 ? 60 LYS C CD 1 ATOM 6852 C CE . LYS C 1 27 ? 11.110 71.163 0.435 1.00 35.79 ? 60 LYS C CE 1 ATOM 6853 N NZ . LYS C 1 27 ? 12.287 71.127 -0.480 1.00 36.47 1 60 LYS C NZ 1 ATOM 6854 N N . VAL C 1 28 ? 7.915 66.770 5.127 1.00 21.58 ? 61 VAL C N 1 ATOM 6855 C CA . VAL C 1 28 ? 6.856 65.771 5.433 1.00 20.79 ? 61 VAL C CA 1 ATOM 6856 C C . VAL C 1 28 ? 5.377 66.313 5.294 1.00 19.90 ? 61 VAL C C 1 ATOM 6857 O O . VAL C 1 28 ? 4.491 65.809 4.509 1.00 17.72 ? 61 VAL C O 1 ATOM 6858 C CB . VAL C 1 28 ? 7.130 65.175 6.815 1.00 20.19 ? 61 VAL C CB 1 ATOM 6859 C CG1 . VAL C 1 28 ? 6.039 64.233 7.209 1.00 20.46 ? 61 VAL C CG1 1 ATOM 6860 C CG2 . VAL C 1 28 ? 8.493 64.454 6.780 1.00 21.41 ? 61 VAL C CG2 1 ATOM 6861 N N . CYS C 1 29 ? 5.115 67.383 6.033 1.00 17.88 ? 62 CYS C N 1 ATOM 6862 C CA . CYS C 1 29 ? 3.754 67.876 6.142 1.00 14.99 ? 62 CYS C CA 1 ATOM 6863 C C . CYS C 1 29 ? 3.894 69.336 6.130 1.00 13.35 ? 62 CYS C C 1 ATOM 6864 O O . CYS C 1 29 ? 4.654 69.843 6.873 1.00 14.44 ? 62 CYS C O 1 ATOM 6865 C CB . CYS C 1 29 ? 3.239 67.446 7.479 1.00 14.89 ? 62 CYS C CB 1 ATOM 6866 S SG . CYS C 1 29 ? 4.270 67.978 8.891 1.00 13.17 ? 62 CYS C SG 1 ATOM 6867 N N . ALA C 1 30 ? 3.211 70.021 5.267 1.00 13.07 ? 63 ALA C N 1 ATOM 6868 C CA . ALA C 1 30 ? 3.127 71.494 5.298 1.00 14.11 ? 63 ALA C CA 1 ATOM 6869 C C . ALA C 1 30 ? 2.642 72.022 6.686 1.00 15.55 ? 63 ALA C C 1 ATOM 6870 O O . ALA C 1 30 ? 3.020 73.085 7.076 1.00 15.56 ? 63 ALA C O 1 ATOM 6871 C CB . ALA C 1 30 ? 2.279 72.042 4.154 1.00 12.50 ? 63 ALA C CB 1 ATOM 6872 N N . SER C 1 31 ? 1.871 71.234 7.450 1.00 18.25 ? 64 SER C N 1 ATOM 6873 C CA . SER C 1 31 ? 1.466 71.627 8.814 1.00 18.71 ? 64 SER C CA 1 ATOM 6874 C C . SER C 1 31 ? 2.665 71.854 9.841 1.00 15.60 ? 64 SER C C 1 ATOM 6875 O O . SER C 1 31 ? 2.507 72.414 10.898 1.00 13.31 ? 64 SER C O 1 ATOM 6876 C CB . SER C 1 31 ? 0.299 70.690 9.330 1.00 21.84 ? 64 SER C CB 1 ATOM 6877 O OG . SER C 1 31 ? 0.660 69.376 9.725 1.00 23.16 ? 64 SER C OG 1 ATOM 6878 N N . SER C 1 32 ? 3.872 71.492 9.473 1.00 14.59 ? 65 SER C N 1 ATOM 6879 C CA . SER C 1 32 ? 5.017 71.787 10.347 1.00 15.30 ? 65 SER C CA 1 ATOM 6880 C C . SER C 1 32 ? 5.634 73.167 10.061 1.00 16.52 ? 65 SER C C 1 ATOM 6881 O O . SER C 1 32 ? 6.548 73.591 10.794 1.00 14.45 ? 65 SER C O 1 ATOM 6882 C CB . SER C 1 32 ? 6.066 70.671 10.257 1.00 14.28 ? 65 SER C CB 1 ATOM 6883 O OG . SER C 1 32 ? 6.931 70.825 9.163 1.00 13.88 ? 65 SER C OG 1 ATOM 6884 N N . LYS C 1 33 ? 5.117 73.794 8.968 1.00 18.38 ? 66 LYS C N 1 ATOM 6885 C CA . LYS C 1 33 ? 5.467 75.132 8.439 1.00 19.36 ? 66 LYS C CA 1 ATOM 6886 C C . LYS C 1 33 ? 6.946 75.315 8.294 1.00 19.09 ? 66 LYS C C 1 ATOM 6887 O O . LYS C 1 33 ? 7.522 76.345 8.642 1.00 19.34 ? 66 LYS C O 1 ATOM 6888 C CB . LYS C 1 33 ? 4.824 76.276 9.248 1.00 22.30 ? 66 LYS C CB 1 ATOM 6889 C CG . LYS C 1 33 ? 3.280 76.284 9.192 1.00 25.50 ? 66 LYS C CG 1 ATOM 6890 C CD . LYS C 1 33 ? 2.672 77.090 10.346 1.00 30.43 ? 66 LYS C CD 1 ATOM 6891 C CE . LYS C 1 33 ? 1.587 76.310 11.118 1.00 34.88 ? 66 LYS C CE 1 ATOM 6892 N NZ . LYS C 1 33 ? 2.091 75.059 11.801 1.00 36.31 1 66 LYS C NZ 1 ATOM 6893 N N . GLY C 1 34 ? 7.557 74.287 7.728 1.00 18.53 ? 67 GLY C N 1 ATOM 6894 C CA . GLY C 1 34 ? 8.974 74.284 7.472 1.00 17.68 ? 67 GLY C CA 1 ATOM 6895 C C . GLY C 1 34 ? 9.810 73.721 8.600 1.00 18.81 ? 67 GLY C C 1 ATOM 6896 O O . GLY C 1 34 ? 10.991 73.406 8.340 1.00 21.84 ? 67 GLY C O 1 ATOM 6897 N N . ALA C 1 35 ? 9.264 73.586 9.829 1.00 17.86 ? 68 ALA C N 1 ATOM 6898 C CA . ALA C 1 35 ? 9.998 72.907 10.919 1.00 17.77 ? 68 ALA C CA 1 ATOM 6899 C C . ALA C 1 35 ? 10.284 71.453 10.493 1.00 19.25 ? 68 ALA C C 1 ATOM 6900 O O . ALA C 1 35 ? 9.565 70.909 9.661 1.00 19.59 ? 68 ALA C O 1 ATOM 6901 C CB . ALA C 1 35 ? 9.223 72.965 12.218 1.00 17.25 ? 68 ALA C CB 1 ATOM 6902 N N . ASN C 1 36 ? 11.392 70.880 10.963 1.00 21.31 ? 69 ASN C N 1 ATOM 6903 C CA . ASN C 1 36 ? 11.683 69.447 10.802 1.00 22.44 ? 69 ASN C CA 1 ATOM 6904 C C . ASN C 1 36 ? 10.690 68.664 11.619 1.00 23.54 ? 69 ASN C C 1 ATOM 6905 O O . ASN C 1 36 ? 10.514 68.882 12.816 1.00 25.18 ? 69 ASN C O 1 ATOM 6906 C CB . ASN C 1 36 ? 13.096 69.040 11.283 1.00 23.57 ? 69 ASN C CB 1 ATOM 6907 C CG . ASN C 1 36 ? 14.139 69.047 10.183 1.00 25.69 ? 69 ASN C CG 1 ATOM 6908 O OD1 . ASN C 1 36 ? 13.915 68.574 9.066 1.00 27.34 ? 69 ASN C OD1 1 ATOM 6909 N ND2 . ASN C 1 36 ? 15.304 69.563 10.512 1.00 30.77 ? 69 ASN C ND2 1 ATOM 6910 N N . ALA C 1 37 ? 10.015 67.752 10.953 1.00 24.69 ? 70 ALA C N 1 ATOM 6911 C CA . ALA C 1 37 ? 9.179 66.796 11.623 1.00 24.40 ? 70 ALA C CA 1 ATOM 6912 C C . ALA C 1 37 ? 10.089 66.085 12.593 1.00 23.24 ? 70 ALA C C 1 ATOM 6913 O O . ALA C 1 37 ? 11.244 65.764 12.257 1.00 21.68 ? 70 ALA C O 1 ATOM 6914 C CB . ALA C 1 37 ? 8.546 65.810 10.620 1.00 24.60 ? 70 ALA C CB 1 ATOM 6915 N N . SER C 1 38 ? 9.556 65.854 13.790 1.00 22.58 ? 71 SER C N 1 ATOM 6916 C CA . SER C 1 38 ? 10.330 65.334 14.887 1.00 23.55 ? 71 SER C CA 1 ATOM 6917 C C . SER C 1 38 ? 10.824 63.911 14.596 1.00 25.69 ? 71 SER C C 1 ATOM 6918 O O . SER C 1 38 ? 12.026 63.671 14.421 1.00 25.35 ? 71 SER C O 1 ATOM 6919 C CB . SER C 1 38 ? 9.488 65.396 16.158 1.00 24.52 ? 71 SER C CB 1 ATOM 6920 O OG . SER C 1 38 ? 10.227 64.900 17.250 1.00 25.34 ? 71 SER C OG 1 ATOM 6921 N N . ASN C 1 39 ? 9.893 62.967 14.514 1.00 28.62 ? 72 ASN C N 1 ATOM 6922 C CA . ASN C 1 39 ? 10.239 61.596 14.205 1.00 30.21 ? 72 ASN C CA 1 ATOM 6923 C C . ASN C 1 39 ? 9.058 60.959 13.524 1.00 27.30 ? 72 ASN C C 1 ATOM 6924 O O . ASN C 1 39 ? 8.309 60.262 14.138 1.00 27.50 ? 72 ASN C O 1 ATOM 6925 C CB . ASN C 1 39 ? 10.620 60.845 15.472 1.00 35.54 ? 72 ASN C CB 1 ATOM 6926 C CG . ASN C 1 39 ? 11.237 59.502 15.176 1.00 40.08 ? 72 ASN C CG 1 ATOM 6927 O OD1 . ASN C 1 39 ? 11.827 59.276 14.105 1.00 45.90 ? 72 ASN C OD1 1 ATOM 6928 N ND2 . ASN C 1 39 ? 11.096 58.595 16.114 1.00 43.47 ? 72 ASN C ND2 1 ATOM 6929 N N . PRO C 1 40 ? 8.877 61.242 12.237 1.00 24.73 ? 73 PRO C N 1 ATOM 6930 C CA . PRO C 1 40 ? 7.626 60.927 11.588 1.00 24.17 ? 73 PRO C CA 1 ATOM 6931 C C . PRO C 1 40 ? 7.510 59.483 11.137 1.00 22.70 ? 73 PRO C C 1 ATOM 6932 O O . PRO C 1 40 ? 8.496 58.808 10.878 1.00 22.40 ? 73 PRO C O 1 ATOM 6933 C CB . PRO C 1 40 ? 7.598 61.906 10.386 1.00 23.96 ? 73 PRO C CB 1 ATOM 6934 C CG . PRO C 1 40 ? 9.052 62.032 10.031 1.00 24.26 ? 73 PRO C CG 1 ATOM 6935 C CD . PRO C 1 40 ? 9.796 61.967 11.341 1.00 24.60 ? 73 PRO C CD 1 ATOM 6936 N N . GLY C 1 41 ? 6.269 59.042 11.044 1.00 22.83 ? 74 GLY C N 1 ATOM 6937 C CA . GLY C 1 41 ? 5.952 57.645 10.862 1.00 22.72 ? 74 GLY C CA 1 ATOM 6938 C C . GLY C 1 41 ? 4.650 57.455 10.118 1.00 23.13 ? 74 GLY C C 1 ATOM 6939 O O . GLY C 1 41 ? 3.998 58.450 9.711 1.00 20.61 ? 74 GLY C O 1 ATOM 6940 N N . PRO C 1 42 ? 4.286 56.165 9.901 1.00 23.36 ? 75 PRO C N 1 ATOM 6941 C CA . PRO C 1 42 ? 3.192 55.946 9.009 1.00 22.41 ? 75 PRO C CA 1 ATOM 6942 C C . PRO C 1 42 ? 1.984 56.571 9.694 1.00 21.71 ? 75 PRO C C 1 ATOM 6943 O O . PRO C 1 42 ? 1.001 56.965 8.982 1.00 23.71 ? 75 PRO C O 1 ATOM 6944 C CB . PRO C 1 42 ? 3.131 54.438 8.863 1.00 21.75 ? 75 PRO C CB 1 ATOM 6945 C CG . PRO C 1 42 ? 3.645 53.952 10.169 1.00 25.27 ? 75 PRO C CG 1 ATOM 6946 C CD . PRO C 1 42 ? 4.781 54.903 10.479 1.00 23.77 ? 75 PRO C CD 1 ATOM 6947 N N . PHE C 1 43 ? 2.062 56.816 11.018 1.00 18.76 ? 76 PHE C N 1 ATOM 6948 C CA . PHE C 1 43 ? 0.851 57.383 11.663 1.00 17.69 ? 76 PHE C CA 1 ATOM 6949 C C . PHE C 1 43 ? 0.799 58.867 11.945 1.00 16.67 ? 76 PHE C C 1 ATOM 6950 O O . PHE C 1 43 ? -0.170 59.338 12.508 1.00 18.87 ? 76 PHE C O 1 ATOM 6951 C CB . PHE C 1 43 ? 0.418 56.522 12.812 1.00 17.48 ? 76 PHE C CB 1 ATOM 6952 C CG . PHE C 1 43 ? -0.124 55.223 12.337 1.00 18.14 ? 76 PHE C CG 1 ATOM 6953 C CD1 . PHE C 1 43 ? -1.403 55.183 11.697 1.00 19.69 ? 76 PHE C CD1 1 ATOM 6954 C CD2 . PHE C 1 43 ? 0.633 54.075 12.401 1.00 17.72 ? 76 PHE C CD2 1 ATOM 6955 C CE1 . PHE C 1 43 ? -1.939 53.988 11.211 1.00 19.87 ? 76 PHE C CE1 1 ATOM 6956 C CE2 . PHE C 1 43 ? 0.125 52.887 11.891 1.00 19.63 ? 76 PHE C CE2 1 ATOM 6957 C CZ . PHE C 1 43 ? -1.157 52.834 11.288 1.00 19.41 ? 76 PHE C CZ 1 ATOM 6958 N N . GLY C 1 44 ? 1.768 59.615 11.440 1.00 14.82 ? 77 GLY C N 1 ATOM 6959 C CA . GLY C 1 44 ? 1.871 60.997 11.761 1.00 14.61 ? 77 GLY C CA 1 ATOM 6960 C C . GLY C 1 44 ? 3.087 61.364 12.615 1.00 15.28 ? 77 GLY C C 1 ATOM 6961 O O . GLY C 1 44 ? 4.020 60.584 12.824 1.00 14.90 ? 77 GLY C O 1 ATOM 6962 N N . ASP C 1 45 ? 3.064 62.608 13.083 1.00 15.68 ? 78 ASP C N 1 ATOM 6963 C CA . ASP C 1 45 ? 4.135 63.211 13.818 1.00 15.06 ? 78 ASP C CA 1 ATOM 6964 C C . ASP C 1 45 ? 3.545 64.296 14.741 1.00 14.61 ? 78 ASP C C 1 ATOM 6965 O O . ASP C 1 45 ? 2.491 64.976 14.429 1.00 13.41 ? 78 ASP C O 1 ATOM 6966 C CB . ASP C 1 45 ? 5.163 63.806 12.846 1.00 15.41 ? 78 ASP C CB 1 ATOM 6967 C CG . ASP C 1 45 ? 6.448 64.227 13.555 1.00 16.19 ? 78 ASP C CG 1 ATOM 6968 O OD1 . ASP C 1 45 ? 7.289 63.331 13.868 1.00 13.68 ? 78 ASP C OD1 1 ATOM 6969 O OD2 . ASP C 1 45 ? 6.552 65.474 13.840 1.00 17.21 -1 78 ASP C OD2 1 ATOM 6970 N N . VAL C 1 46 ? 4.196 64.483 15.881 1.00 13.95 ? 79 VAL C N 1 ATOM 6971 C CA . VAL C 1 46 ? 3.674 65.506 16.793 1.00 14.53 ? 79 VAL C CA 1 ATOM 6972 C C . VAL C 1 46 ? 3.695 66.972 16.260 1.00 14.64 ? 79 VAL C C 1 ATOM 6973 O O . VAL C 1 46 ? 2.902 67.844 16.790 1.00 15.35 ? 79 VAL C O 1 ATOM 6974 C CB . VAL C 1 46 ? 4.292 65.411 18.175 1.00 14.74 ? 79 VAL C CB 1 ATOM 6975 C CG1 . VAL C 1 46 ? 3.897 64.103 18.769 1.00 14.44 ? 79 VAL C CG1 1 ATOM 6976 C CG2 . VAL C 1 46 ? 5.825 65.564 18.136 1.00 15.55 ? 79 VAL C CG2 1 ATOM 6977 N N . LEU C 1 47 ? 4.556 67.239 15.237 1.00 13.57 ? 80 LEU C N 1 ATOM 6978 C CA . LEU C 1 47 ? 4.670 68.557 14.594 1.00 12.62 ? 80 LEU C CA 1 ATOM 6979 C C . LEU C 1 47 ? 3.812 68.615 13.327 1.00 13.29 ? 80 LEU C C 1 ATOM 6980 O O . LEU C 1 47 ? 3.826 69.581 12.605 1.00 12.65 ? 80 LEU C O 1 ATOM 6981 C CB . LEU C 1 47 ? 6.127 68.828 14.258 1.00 12.75 ? 80 LEU C CB 1 ATOM 6982 C CG . LEU C 1 47 ? 7.003 69.717 15.178 1.00 13.87 ? 80 LEU C CG 1 ATOM 6983 C CD1 . LEU C 1 47 ? 6.444 70.157 16.563 1.00 13.83 ? 80 LEU C CD1 1 ATOM 6984 C CD2 . LEU C 1 47 ? 8.368 69.091 15.339 1.00 13.95 ? 80 LEU C CD2 1 ATOM 6985 N N . CYS C 1 48 ? 3.089 67.539 13.024 1.00 14.16 ? 81 CYS C N 1 ATOM 6986 C CA . CYS C 1 48 ? 2.192 67.520 11.876 1.00 14.98 ? 81 CYS C CA 1 ATOM 6987 C C . CYS C 1 48 ? 0.684 67.281 12.225 1.00 13.93 ? 81 CYS C C 1 ATOM 6988 O O . CYS C 1 48 ? 0.302 66.941 13.359 1.00 13.17 ? 81 CYS C O 1 ATOM 6989 C CB . CYS C 1 48 ? 2.582 66.463 10.853 1.00 15.17 ? 81 CYS C CB 1 ATOM 6990 S SG . CYS C 1 48 ? 4.226 66.425 10.173 1.00 17.01 ? 81 CYS C SG 1 ATOM 6991 N N . ASP C 1 49 ? -0.132 67.506 11.203 1.00 12.90 ? 82 ASP C N 1 ATOM 6992 C CA . ASP C 1 49 ? -1.498 67.299 11.313 1.00 12.89 ? 82 ASP C CA 1 ATOM 6993 C C . ASP C 1 49 ? -1.781 65.924 10.789 1.00 12.86 ? 82 ASP C C 1 ATOM 6994 O O . ASP C 1 49 ? -0.874 65.218 10.445 1.00 12.90 ? 82 ASP C O 1 ATOM 6995 C CB . ASP C 1 49 ? -2.272 68.446 10.634 1.00 12.86 ? 82 ASP C CB 1 ATOM 6996 C CG . ASP C 1 49 ? -2.927 69.421 11.670 1.00 12.37 ? 82 ASP C CG 1 ATOM 6997 O OD1 . ASP C 1 49 ? -3.335 68.933 12.727 1.00 10.69 ? 82 ASP C OD1 1 ATOM 6998 O OD2 . ASP C 1 49 ? -3.028 70.675 11.432 1.00 13.47 -1 82 ASP C OD2 1 ATOM 6999 N N . SER C 1 50 ? -2.996 65.514 10.831 1.00 13.32 ? 83 SER C N 1 ATOM 7000 C CA . SER C 1 50 ? -3.273 64.202 10.451 1.00 14.74 ? 83 SER C CA 1 ATOM 7001 C C . SER C 1 50 ? -3.121 63.786 9.047 1.00 15.27 ? 83 SER C C 1 ATOM 7002 O O . SER C 1 50 ? -3.683 64.351 8.177 1.00 15.87 ? 83 SER C O 1 ATOM 7003 C CB . SER C 1 50 ? -4.674 63.872 10.846 1.00 15.82 ? 83 SER C CB 1 ATOM 7004 O OG . SER C 1 50 ? -4.854 64.084 12.186 1.00 16.42 ? 83 SER C OG 1 ATOM 7005 N N . PRO C 1 51 ? -2.297 62.681 8.903 1.00 15.47 ? 84 PRO C N 1 ATOM 7006 C CA . PRO C 1 51 ? -2.285 62.097 7.575 1.00 15.24 ? 84 PRO C CA 1 ATOM 7007 C C . PRO C 1 51 ? -3.554 61.281 7.458 1.00 16.26 ? 84 PRO C C 1 ATOM 7008 O O . PRO C 1 51 ? -4.195 61.031 8.425 1.00 16.58 ? 84 PRO C O 1 ATOM 7009 C CB . PRO C 1 51 ? -1.100 61.155 7.575 1.00 14.68 ? 84 PRO C CB 1 ATOM 7010 C CG . PRO C 1 51 ? -0.768 60.869 8.938 1.00 15.00 ? 84 PRO C CG 1 ATOM 7011 C CD . PRO C 1 51 ? -1.246 61.966 9.757 1.00 14.81 ? 84 PRO C CD 1 ATOM 7012 N N . TYR C 1 52 ? -3.904 60.903 6.261 1.00 16.82 ? 85 TYR C N 1 ATOM 7013 C CA . TYR C 1 52 ? -5.084 60.163 5.975 1.00 18.03 ? 85 TYR C CA 1 ATOM 7014 C C . TYR C 1 52 ? -5.086 58.859 6.769 1.00 19.57 ? 85 TYR C C 1 ATOM 7015 O O . TYR C 1 52 ? -6.122 58.548 7.373 1.00 19.39 ? 85 TYR C O 1 ATOM 7016 C CB . TYR C 1 52 ? -5.284 59.925 4.461 1.00 17.83 ? 85 TYR C CB 1 ATOM 7017 C CG . TYR C 1 52 ? -6.683 59.478 4.123 1.00 16.97 ? 85 TYR C CG 1 ATOM 7018 C CD1 . TYR C 1 52 ? -7.752 60.358 4.193 1.00 17.77 ? 85 TYR C CD1 1 ATOM 7019 C CD2 . TYR C 1 52 ? -6.936 58.193 3.763 1.00 17.37 ? 85 TYR C CD2 1 ATOM 7020 C CE1 . TYR C 1 52 ? -9.032 59.941 3.870 1.00 18.39 ? 85 TYR C CE1 1 ATOM 7021 C CE2 . TYR C 1 52 ? -8.208 57.767 3.410 1.00 16.72 ? 85 TYR C CE2 1 ATOM 7022 C CZ . TYR C 1 52 ? -9.233 58.627 3.508 1.00 17.30 ? 85 TYR C CZ 1 ATOM 7023 O OH . TYR C 1 52 ? -10.471 58.199 3.281 1.00 17.68 ? 85 TYR C OH 1 ATOM 7024 N N . GLN C 1 53 ? -3.937 58.182 6.842 1.00 19.48 ? 86 GLN C N 1 ATOM 7025 C CA . GLN C 1 53 ? -3.827 56.841 7.454 1.00 23.40 ? 86 GLN C CA 1 ATOM 7026 C C . GLN C 1 53 ? -4.352 56.909 8.922 1.00 24.85 ? 86 GLN C C 1 ATOM 7027 O O . GLN C 1 53 ? -5.052 55.978 9.382 1.00 24.55 ? 86 GLN C O 1 ATOM 7028 C CB . GLN C 1 53 ? -2.358 56.301 7.361 1.00 27.91 ? 86 GLN C CB 1 ATOM 7029 C CG . GLN C 1 53 ? -2.095 54.798 7.136 1.00 34.07 ? 86 GLN C CG 1 ATOM 7030 C CD . GLN C 1 53 ? -1.018 54.485 6.004 1.00 43.73 ? 86 GLN C CD 1 ATOM 7031 O OE1 . GLN C 1 53 ? -1.311 53.805 4.981 1.00 46.14 ? 86 GLN C OE1 1 ATOM 7032 N NE2 . GLN C 1 53 ? 0.210 54.988 6.182 1.00 42.52 ? 86 GLN C NE2 1 ATOM 7033 N N . LEU C 1 54 ? -4.052 58.025 9.627 1.00 22.92 ? 87 LEU C N 1 ATOM 7034 C CA . LEU C 1 54 ? -4.477 58.263 11.041 1.00 20.20 ? 87 LEU C CA 1 ATOM 7035 C C . LEU C 1 54 ? -6.032 58.286 11.157 1.00 19.76 ? 87 LEU C C 1 ATOM 7036 O O . LEU C 1 54 ? -6.702 57.414 11.823 1.00 17.92 ? 87 LEU C O 1 ATOM 7037 C CB . LEU C 1 54 ? -3.808 59.585 11.591 1.00 19.64 ? 87 LEU C CB 1 ATOM 7038 C CG . LEU C 1 54 ? -4.197 60.016 12.990 1.00 19.73 ? 87 LEU C CG 1 ATOM 7039 C CD1 . LEU C 1 54 ? -3.924 58.844 13.952 1.00 20.69 ? 87 LEU C CD1 1 ATOM 7040 C CD2 . LEU C 1 54 ? -3.467 61.257 13.465 1.00 19.33 ? 87 LEU C CD2 1 ATOM 7041 N N . ILE C 1 55 ? -6.599 59.270 10.449 1.00 19.25 ? 88 ILE C N 1 ATOM 7042 C CA . ILE C 1 55 ? -8.059 59.498 10.409 1.00 18.04 ? 88 ILE C CA 1 ATOM 7043 C C . ILE C 1 55 ? -8.741 58.111 10.125 1.00 17.97 ? 88 ILE C C 1 ATOM 7044 O O . ILE C 1 55 ? -9.775 57.738 10.746 1.00 15.45 ? 88 ILE C O 1 ATOM 7045 C CB . ILE C 1 55 ? -8.530 60.532 9.310 1.00 17.01 ? 88 ILE C CB 1 ATOM 7046 C CG1 . ILE C 1 55 ? -7.686 61.851 9.150 1.00 17.15 ? 88 ILE C CG1 1 ATOM 7047 C CG2 . ILE C 1 55 ? -10.009 60.790 9.437 1.00 16.71 ? 88 ILE C CG2 1 ATOM 7048 C CD1 . ILE C 1 55 ? -7.953 63.035 10.039 1.00 17.02 ? 88 ILE C CD1 1 ATOM 7049 N N . LEU C 1 56 ? -8.160 57.374 9.167 1.00 18.04 ? 89 LEU C N 1 ATOM 7050 C CA . LEU C 1 56 ? -8.780 56.151 8.653 1.00 18.22 ? 89 LEU C CA 1 ATOM 7051 C C . LEU C 1 56 ? -8.564 55.047 9.713 1.00 17.75 ? 89 LEU C C 1 ATOM 7052 O O . LEU C 1 56 ? -9.514 54.282 10.017 1.00 17.20 ? 89 LEU C O 1 ATOM 7053 C CB . LEU C 1 56 ? -8.270 55.785 7.244 1.00 18.04 ? 89 LEU C CB 1 ATOM 7054 C CG . LEU C 1 56 ? -8.794 54.597 6.468 1.00 18.47 ? 89 LEU C CG 1 ATOM 7055 C CD1 . LEU C 1 56 ? -10.269 54.893 6.170 1.00 20.72 ? 89 LEU C CD1 1 ATOM 7056 C CD2 . LEU C 1 56 ? -7.908 54.410 5.209 1.00 18.73 ? 89 LEU C CD2 1 ATOM 7057 N N . SER C 1 57 ? -7.400 55.024 10.350 1.00 16.32 ? 90 SER C N 1 ATOM 7058 C CA . SER C 1 57 ? -7.213 54.097 11.458 1.00 16.23 ? 90 SER C CA 1 ATOM 7059 C C . SER C 1 57 ? -8.239 54.344 12.564 1.00 16.99 ? 90 SER C C 1 ATOM 7060 O O . SER C 1 57 ? -8.708 53.371 13.221 1.00 15.13 ? 90 SER C O 1 ATOM 7061 C CB . SER C 1 57 ? -5.822 54.201 12.052 1.00 16.94 ? 90 SER C CB 1 ATOM 7062 O OG . SER C 1 57 ? -5.746 55.093 13.186 1.00 19.10 ? 90 SER C OG 1 ATOM 7063 N N . ALA C 1 58 ? -8.593 55.615 12.803 1.00 16.69 ? 91 ALA C N 1 ATOM 7064 C CA . ALA C 1 58 ? -9.539 55.906 13.921 1.00 18.90 ? 91 ALA C CA 1 ATOM 7065 C C . ALA C 1 58 ? -10.936 55.298 13.680 1.00 18.34 ? 91 ALA C C 1 ATOM 7066 O O . ALA C 1 58 ? -11.534 54.646 14.553 1.00 16.89 ? 91 ALA C O 1 ATOM 7067 C CB . ALA C 1 58 ? -9.634 57.428 14.223 1.00 19.23 ? 91 ALA C CB 1 ATOM 7068 N N . PHE C 1 59 ? -11.417 55.528 12.469 1.00 20.40 ? 92 PHE C N 1 ATOM 7069 C CA . PHE C 1 59 ? -12.707 55.027 12.024 1.00 21.73 ? 92 PHE C CA 1 ATOM 7070 C C . PHE C 1 59 ? -12.725 53.494 11.854 1.00 20.36 ? 92 PHE C C 1 ATOM 7071 O O . PHE C 1 59 ? -13.733 52.820 12.013 1.00 18.55 ? 92 PHE C O 1 ATOM 7072 C CB . PHE C 1 59 ? -13.074 55.728 10.724 1.00 22.27 ? 92 PHE C CB 1 ATOM 7073 C CG . PHE C 1 59 ? -13.375 57.194 10.885 1.00 22.90 ? 92 PHE C CG 1 ATOM 7074 C CD1 . PHE C 1 59 ? -14.285 57.629 11.824 1.00 23.81 ? 92 PHE C CD1 1 ATOM 7075 C CD2 . PHE C 1 59 ? -12.809 58.112 10.054 1.00 24.70 ? 92 PHE C CD2 1 ATOM 7076 C CE1 . PHE C 1 59 ? -14.609 58.959 11.940 1.00 24.85 ? 92 PHE C CE1 1 ATOM 7077 C CE2 . PHE C 1 59 ? -13.121 59.453 10.165 1.00 26.46 ? 92 PHE C CE2 1 ATOM 7078 C CZ . PHE C 1 59 ? -14.021 59.877 11.105 1.00 25.72 ? 92 PHE C CZ 1 ATOM 7079 N N . ASP C 1 60 ? -11.569 52.958 11.553 1.00 20.61 ? 93 ASP C N 1 ATOM 7080 C CA . ASP C 1 60 ? -11.437 51.570 11.373 1.00 21.08 ? 93 ASP C CA 1 ATOM 7081 C C . ASP C 1 60 ? -11.508 50.876 12.731 1.00 19.72 ? 93 ASP C C 1 ATOM 7082 O O . ASP C 1 60 ? -12.024 49.792 12.835 1.00 19.45 ? 93 ASP C O 1 ATOM 7083 C CB . ASP C 1 60 ? -10.182 51.313 10.577 1.00 22.17 ? 93 ASP C CB 1 ATOM 7084 C CG . ASP C 1 60 ? -9.927 49.884 10.424 1.00 26.74 ? 93 ASP C CG 1 ATOM 7085 O OD1 . ASP C 1 60 ? -10.557 49.262 9.560 1.00 31.71 ? 93 ASP C OD1 1 ATOM 7086 O OD2 . ASP C 1 60 ? -9.118 49.339 11.198 1.00 32.19 -1 93 ASP C OD2 1 ATOM 7087 N N . PHE C 1 61 ? -11.035 51.527 13.775 1.00 21.30 ? 94 PHE C N 1 ATOM 7088 C CA . PHE C 1 61 ? -11.107 51.017 15.155 1.00 23.17 ? 94 PHE C CA 1 ATOM 7089 C C . PHE C 1 61 ? -12.538 51.017 15.636 1.00 23.46 ? 94 PHE C C 1 ATOM 7090 O O . PHE C 1 61 ? -13.042 50.065 16.183 1.00 24.15 ? 94 PHE C O 1 ATOM 7091 C CB . PHE C 1 61 ? -10.303 51.919 16.111 1.00 25.13 ? 94 PHE C CB 1 ATOM 7092 C CG . PHE C 1 61 ? -10.698 51.770 17.551 1.00 26.16 ? 94 PHE C CG 1 ATOM 7093 C CD1 . PHE C 1 61 ? -10.348 50.628 18.265 1.00 27.14 ? 94 PHE C CD1 1 ATOM 7094 C CD2 . PHE C 1 61 ? -11.457 52.733 18.185 1.00 26.97 ? 94 PHE C CD2 1 ATOM 7095 C CE1 . PHE C 1 61 ? -10.732 50.469 19.593 1.00 28.42 ? 94 PHE C CE1 1 ATOM 7096 C CE2 . PHE C 1 61 ? -11.846 52.584 19.524 1.00 26.43 ? 94 PHE C CE2 1 ATOM 7097 C CZ . PHE C 1 61 ? -11.477 51.447 20.227 1.00 27.13 ? 94 PHE C CZ 1 ATOM 7098 N N . ILE C 1 62 ? -13.178 52.135 15.488 1.00 23.53 ? 95 ILE C N 1 ATOM 7099 C CA . ILE C 1 62 ? -14.590 52.158 15.677 1.00 25.82 ? 95 ILE C CA 1 ATOM 7100 C C . ILE C 1 62 ? -15.305 50.925 15.021 1.00 27.04 ? 95 ILE C C 1 ATOM 7101 O O . ILE C 1 62 ? -15.997 50.188 15.719 1.00 23.54 ? 95 ILE C O 1 ATOM 7102 C CB . ILE C 1 62 ? -15.111 53.517 15.164 1.00 27.38 ? 95 ILE C CB 1 ATOM 7103 C CG1 . ILE C 1 62 ? -14.622 54.633 16.120 1.00 26.51 ? 95 ILE C CG1 1 ATOM 7104 C CG2 . ILE C 1 62 ? -16.630 53.487 14.985 1.00 28.59 ? 95 ILE C CG2 1 ATOM 7105 C CD1 . ILE C 1 62 ? -15.331 55.977 15.967 1.00 29.29 ? 95 ILE C CD1 1 ATOM 7106 N N . LYS C 1 63 ? -15.107 50.678 13.704 1.00 31.26 ? 96 LYS C N 1 ATOM 7107 C CA . LYS C 1 63 ? -15.756 49.535 12.966 1.00 28.82 ? 96 LYS C CA 1 ATOM 7108 C C . LYS C 1 63 ? -15.504 48.175 13.576 1.00 29.03 ? 96 LYS C C 1 ATOM 7109 O O . LYS C 1 63 ? -16.311 47.281 13.405 1.00 32.06 ? 96 LYS C O 1 ATOM 7110 C CB . LYS C 1 63 ? -15.287 49.445 11.527 1.00 28.80 ? 96 LYS C CB 1 ATOM 7111 C CG . LYS C 1 63 ? -16.207 50.020 10.479 1.00 31.86 ? 96 LYS C CG 1 ATOM 7112 C CD . LYS C 1 63 ? -15.406 50.068 9.176 1.00 36.56 ? 96 LYS C CD 1 ATOM 7113 C CE . LYS C 1 63 ? -16.239 50.304 7.920 1.00 37.78 ? 96 LYS C CE 1 ATOM 7114 N NZ . LYS C 1 63 ? -15.791 49.395 6.801 1.00 39.84 1 96 LYS C NZ 1 ATOM 7115 N N . ASN C 1 64 ? -14.354 48.026 14.231 1.00 28.72 ? 97 ASN C N 1 ATOM 7116 C CA . ASN C 1 64 ? -13.844 46.766 14.751 1.00 28.79 ? 97 ASN C CA 1 ATOM 7117 C C . ASN C 1 64 ? -13.626 46.802 16.271 1.00 27.71 ? 97 ASN C C 1 ATOM 7118 O O . ASN C 1 64 ? -12.891 46.000 16.826 1.00 33.57 ? 97 ASN C O 1 ATOM 7119 C CB . ASN C 1 64 ? -12.495 46.458 14.072 1.00 31.86 ? 97 ASN C CB 1 ATOM 7120 C CG . ASN C 1 64 ? -12.621 46.207 12.585 1.00 33.48 ? 97 ASN C CG 1 ATOM 7121 O OD1 . ASN C 1 64 ? -12.277 45.144 12.110 1.00 36.89 ? 97 ASN C OD1 1 ATOM 7122 N ND2 . ASN C 1 64 ? -13.110 47.180 11.851 1.00 35.54 ? 97 ASN C ND2 1 ATOM 7123 N N . SER C 1 65 ? -14.233 47.750 16.958 1.00 26.00 ? 98 SER C N 1 ATOM 7124 C CA . SER C 1 65 ? -14.080 47.889 18.397 1.00 24.19 ? 98 SER C CA 1 ATOM 7125 C C . SER C 1 65 ? -15.015 46.946 19.100 1.00 23.61 ? 98 SER C C 1 ATOM 7126 O O . SER C 1 65 ? -15.068 46.887 20.332 1.00 22.52 ? 98 SER C O 1 ATOM 7127 C CB . SER C 1 65 ? -14.497 49.301 18.795 1.00 25.73 ? 98 SER C CB 1 ATOM 7128 O OG . SER C 1 65 ? -15.869 49.533 18.458 1.00 26.12 ? 98 SER C OG 1 ATOM 7129 N N . GLY C 1 66 ? -15.851 46.304 18.307 1.00 24.07 ? 99 GLY C N 1 ATOM 7130 C CA . GLY C 1 66 ? -16.928 45.548 18.839 1.00 26.06 ? 99 GLY C CA 1 ATOM 7131 C C . GLY C 1 66 ? -17.790 46.368 19.767 1.00 26.19 ? 99 GLY C C 1 ATOM 7132 O O . GLY C 1 66 ? -18.270 45.828 20.733 1.00 30.91 ? 99 GLY C O 1 ATOM 7133 N N . GLN C 1 67 ? -17.963 47.658 19.491 1.00 24.36 ? 100 GLN C N 1 ATOM 7134 C CA . GLN C 1 67 ? -18.958 48.480 20.173 1.00 23.40 ? 100 GLN C CA 1 ATOM 7135 C C . GLN C 1 67 ? -20.009 48.929 19.190 1.00 23.76 ? 100 GLN C C 1 ATOM 7136 O O . GLN C 1 67 ? -19.736 49.263 18.078 1.00 25.21 ? 100 GLN C O 1 ATOM 7137 C CB . GLN C 1 67 ? -18.338 49.711 20.762 1.00 22.98 ? 100 GLN C CB 1 ATOM 7138 C CG . GLN C 1 67 ? -17.369 49.412 21.889 1.00 23.48 ? 100 GLN C CG 1 ATOM 7139 C CD . GLN C 1 67 ? -18.027 49.324 23.233 1.00 21.88 ? 100 GLN C CD 1 ATOM 7140 O OE1 . GLN C 1 67 ? -19.217 49.158 23.331 1.00 23.04 ? 100 GLN C OE1 1 ATOM 7141 N NE2 . GLN C 1 67 ? -17.244 49.448 24.276 1.00 22.35 ? 100 GLN C NE2 1 ATOM 7142 N N . GLU C 1 68 ? -21.217 48.942 19.666 1.00 26.06 ? 101 GLU C N 1 ATOM 7143 C CA . GLU C 1 68 ? -22.398 49.212 18.929 1.00 28.25 ? 101 GLU C CA 1 ATOM 7144 C C . GLU C 1 68 ? -22.690 50.701 19.174 1.00 27.21 ? 101 GLU C C 1 ATOM 7145 O O . GLU C 1 68 ? -22.489 51.171 20.315 1.00 31.91 ? 101 GLU C O 1 ATOM 7146 C CB . GLU C 1 68 ? -23.490 48.252 19.471 1.00 33.82 ? 101 GLU C CB 1 ATOM 7147 C CG . GLU C 1 68 ? -23.953 48.408 20.975 1.00 40.19 ? 101 GLU C CG 1 ATOM 7148 C CD . GLU C 1 68 ? -23.094 47.734 22.117 1.00 44.66 ? 101 GLU C CD 1 ATOM 7149 O OE1 . GLU C 1 68 ? -21.948 47.267 21.901 1.00 43.58 ? 101 GLU C OE1 1 ATOM 7150 O OE2 . GLU C 1 68 ? -23.568 47.694 23.300 1.00 51.86 -1 101 GLU C OE2 1 ATOM 7151 N N . ALA C 1 69 ? -23.105 51.466 18.155 1.00 22.04 ? 102 ALA C N 1 ATOM 7152 C CA . ALA C 1 69 ? -23.579 52.840 18.402 1.00 22.00 ? 102 ALA C CA 1 ATOM 7153 C C . ALA C 1 69 ? -24.799 53.317 17.631 1.00 20.49 ? 102 ALA C C 1 ATOM 7154 O O . ALA C 1 69 ? -24.915 53.002 16.476 1.00 20.98 ? 102 ALA C O 1 ATOM 7155 C CB . ALA C 1 69 ? -22.440 53.841 18.167 1.00 23.99 ? 102 ALA C CB 1 ATOM 7156 N N . SER C 1 70 ? -25.640 54.154 18.241 1.00 17.74 ? 103 SER C N 1 ATOM 7157 C CA . SER C 1 70 ? -26.850 54.628 17.600 1.00 19.76 ? 103 SER C CA 1 ATOM 7158 C C . SER C 1 70 ? -26.724 55.985 16.871 1.00 21.12 ? 103 SER C C 1 ATOM 7159 O O . SER C 1 70 ? -27.660 56.482 16.190 1.00 18.47 ? 103 SER C O 1 ATOM 7160 C CB . SER C 1 70 ? -27.920 54.772 18.691 1.00 21.62 ? 103 SER C CB 1 ATOM 7161 O OG . SER C 1 70 ? -28.037 53.557 19.375 1.00 25.17 ? 103 SER C OG 1 ATOM 7162 N N . PHE C 1 71 ? -25.614 56.647 17.130 1.00 23.23 ? 104 PHE C N 1 ATOM 7163 C CA . PHE C 1 71 ? -25.225 57.842 16.376 1.00 25.55 ? 104 PHE C CA 1 ATOM 7164 C C . PHE C 1 71 ? -23.799 58.313 16.710 1.00 24.00 ? 104 PHE C C 1 ATOM 7165 O O . PHE C 1 71 ? -23.060 57.691 17.577 1.00 25.30 ? 104 PHE C O 1 ATOM 7166 C CB . PHE C 1 71 ? -26.228 58.991 16.538 1.00 25.10 ? 104 PHE C CB 1 ATOM 7167 C CG . PHE C 1 71 ? -26.383 59.465 17.948 1.00 27.29 ? 104 PHE C CG 1 ATOM 7168 C CD1 . PHE C 1 71 ? -27.142 58.715 18.882 1.00 25.58 ? 104 PHE C CD1 1 ATOM 7169 C CD2 . PHE C 1 71 ? -25.791 60.672 18.360 1.00 26.65 ? 104 PHE C CD2 1 ATOM 7170 C CE1 . PHE C 1 71 ? -27.308 59.185 20.167 1.00 24.21 ? 104 PHE C CE1 1 ATOM 7171 C CE2 . PHE C 1 71 ? -25.953 61.117 19.671 1.00 26.08 ? 104 PHE C CE2 1 ATOM 7172 C CZ . PHE C 1 71 ? -26.714 60.391 20.551 1.00 24.87 ? 104 PHE C CZ 1 ATOM 7173 N N . MET C 1 72 ? -23.402 59.366 15.993 1.00 20.87 ? 105 MET C N 1 ATOM 7174 C CA . MET C 1 72 ? -22.053 59.886 16.176 1.00 22.93 ? 105 MET C CA 1 ATOM 7175 C C . MET C 1 72 ? -22.132 61.391 16.118 1.00 17.97 ? 105 MET C C 1 ATOM 7176 O O . MET C 1 72 ? -22.856 61.894 15.325 1.00 15.52 ? 105 MET C O 1 ATOM 7177 C CB . MET C 1 72 ? -21.043 59.250 15.156 1.00 26.19 ? 105 MET C CB 1 ATOM 7178 C CG . MET C 1 72 ? -19.693 59.993 14.986 1.00 29.26 ? 105 MET C CG 1 ATOM 7179 S SD . MET C 1 72 ? -18.565 59.452 13.644 1.00 29.89 ? 105 MET C SD 1 ATOM 7180 C CE . MET C 1 72 ? -17.490 58.410 14.659 1.00 29.04 ? 105 MET C CE 1 ATOM 7181 N N . ILE C 1 73 ? -21.487 62.038 17.095 1.00 16.35 ? 106 ILE C N 1 ATOM 7182 C CA A ILE C 1 73 ? -21.215 63.490 17.128 0.50 15.73 ? 106 ILE C CA 1 ATOM 7183 C CA B ILE C 1 73 ? -21.251 63.491 17.048 0.50 15.79 ? 106 ILE C CA 1 ATOM 7184 C C . ILE C 1 73 ? -19.803 63.757 16.578 1.00 15.18 ? 106 ILE C C 1 ATOM 7185 O O . ILE C 1 73 ? -18.897 63.087 16.972 1.00 14.34 ? 106 ILE C O 1 ATOM 7186 C CB A ILE C 1 73 ? -21.294 64.064 18.580 0.50 14.72 ? 106 ILE C CB 1 ATOM 7187 C CB B ILE C 1 73 ? -21.612 64.248 18.380 0.50 14.84 ? 106 ILE C CB 1 ATOM 7188 C CG1 A ILE C 1 73 ? -22.716 64.120 19.057 0.50 14.25 ? 106 ILE C CG1 1 ATOM 7189 C CG1 B ILE C 1 73 ? -20.700 63.892 19.534 0.50 14.30 ? 106 ILE C CG1 1 ATOM 7190 C CG2 A ILE C 1 73 ? -20.862 65.512 18.611 0.50 14.55 ? 106 ILE C CG2 1 ATOM 7191 C CG2 B ILE C 1 73 ? -23.027 63.940 18.812 0.50 14.65 ? 106 ILE C CG2 1 ATOM 7192 C CD1 A ILE C 1 73 ? -23.456 65.239 18.364 0.50 14.10 ? 106 ILE C CD1 1 ATOM 7193 C CD1 B ILE C 1 73 ? -20.958 64.797 20.712 0.50 14.33 ? 106 ILE C CD1 1 ATOM 7194 N N . TRP C 1 74 ? -19.638 64.761 15.709 1.00 16.34 ? 107 TRP C N 1 ATOM 7195 C CA . TRP C 1 74 ? -18.352 65.091 15.025 1.00 17.14 ? 107 TRP C CA 1 ATOM 7196 C C . TRP C 1 74 ? -18.216 66.618 14.999 1.00 16.10 ? 107 TRP C C 1 ATOM 7197 O O . TRP C 1 74 ? -18.890 67.279 14.227 1.00 16.25 ? 107 TRP C O 1 ATOM 7198 C CB . TRP C 1 74 ? -18.412 64.499 13.622 1.00 18.23 ? 107 TRP C CB 1 ATOM 7199 C CG . TRP C 1 74 ? -17.521 65.036 12.601 1.00 19.37 ? 107 TRP C CG 1 ATOM 7200 C CD1 . TRP C 1 74 ? -16.253 65.406 12.772 1.00 20.36 ? 107 TRP C CD1 1 ATOM 7201 C CD2 . TRP C 1 74 ? -17.806 65.162 11.161 1.00 22.67 ? 107 TRP C CD2 1 ATOM 7202 N NE1 . TRP C 1 74 ? -15.695 65.771 11.537 1.00 24.51 ? 107 TRP C NE1 1 ATOM 7203 C CE2 . TRP C 1 74 ? -16.638 65.646 10.547 1.00 22.70 ? 107 TRP C CE2 1 ATOM 7204 C CE3 . TRP C 1 74 ? -18.930 64.865 10.333 1.00 23.56 ? 107 TRP C CE3 1 ATOM 7205 C CZ2 . TRP C 1 74 ? -16.565 65.903 9.173 1.00 21.69 ? 107 TRP C CZ2 1 ATOM 7206 C CZ3 . TRP C 1 74 ? -18.855 65.148 8.947 1.00 21.46 ? 107 TRP C CZ3 1 ATOM 7207 C CH2 . TRP C 1 74 ? -17.687 65.671 8.402 1.00 21.80 ? 107 TRP C CH2 1 ATOM 7208 N N . THR C 1 75 ? -17.491 67.183 15.952 1.00 16.11 ? 108 THR C N 1 ATOM 7209 C CA . THR C 1 75 ? -17.450 68.613 16.214 1.00 14.78 ? 108 THR C CA 1 ATOM 7210 C C . THR C 1 75 ? -16.510 69.584 15.537 1.00 14.61 ? 108 THR C C 1 ATOM 7211 O O . THR C 1 75 ? -16.218 70.604 16.018 1.00 14.38 ? 108 THR C O 1 ATOM 7212 C CB . THR C 1 75 ? -17.775 68.950 17.690 1.00 14.87 ? 108 THR C CB 1 ATOM 7213 O OG1 . THR C 1 75 ? -17.054 68.131 18.598 1.00 12.86 ? 108 THR C OG1 1 ATOM 7214 C CG2 . THR C 1 75 ? -19.263 68.745 17.935 1.00 15.90 ? 108 THR C CG2 1 ATOM 7215 N N . GLY C 1 76 ? -16.099 69.212 14.368 1.00 14.49 ? 109 GLY C N 1 ATOM 7216 C CA . GLY C 1 76 ? -15.360 70.076 13.528 1.00 14.85 ? 109 GLY C CA 1 ATOM 7217 C C . GLY C 1 76 ? -13.924 70.122 13.437 1.00 13.92 ? 109 GLY C C 1 ATOM 7218 O O . GLY C 1 76 ? -13.278 69.417 14.049 1.00 14.67 ? 109 GLY C O 1 ATOM 7219 N N . ASP C 1 77 ? -13.464 71.033 12.635 1.00 13.25 ? 110 ASP C N 1 ATOM 7220 C CA . ASP C 1 77 ? -12.043 71.235 12.294 1.00 11.89 ? 110 ASP C CA 1 ATOM 7221 C C . ASP C 1 77 ? -11.235 70.280 11.352 1.00 11.82 ? 110 ASP C C 1 ATOM 7222 O O . ASP C 1 77 ? -10.145 69.884 11.638 1.00 14.03 ? 110 ASP C O 1 ATOM 7223 C CB . ASP C 1 77 ? -11.309 71.508 13.586 1.00 11.31 ? 110 ASP C CB 1 ATOM 7224 C CG . ASP C 1 77 ? -11.069 72.923 13.794 1.00 10.34 ? 110 ASP C CG 1 ATOM 7225 O OD1 . ASP C 1 77 ? -11.809 73.789 13.254 1.00 9.26 ? 110 ASP C OD1 1 ATOM 7226 O OD2 . ASP C 1 77 ? -10.129 73.143 14.547 1.00 9.79 -1 110 ASP C OD2 1 ATOM 7227 N N . SER C 1 78 ? -11.773 69.956 10.221 1.00 11.37 ? 111 SER C N 1 ATOM 7228 C CA . SER C 1 78 ? -11.144 69.015 9.322 1.00 12.02 ? 111 SER C CA 1 ATOM 7229 C C . SER C 1 78 ? -9.955 69.469 8.524 1.00 12.78 ? 111 SER C C 1 ATOM 7230 O O . SER C 1 78 ? -9.070 68.608 8.282 1.00 12.62 ? 111 SER C O 1 ATOM 7231 C CB . SER C 1 78 ? -12.234 68.505 8.353 1.00 11.75 ? 111 SER C CB 1 ATOM 7232 O OG . SER C 1 78 ? -13.260 67.833 9.072 1.00 12.78 ? 111 SER C OG 1 ATOM 7233 N N . PRO C 1 79 ? -9.934 70.778 8.087 1.00 13.44 ? 112 PRO C N 1 ATOM 7234 C CA . PRO C 1 79 ? -8.793 71.259 7.362 1.00 13.43 ? 112 PRO C CA 1 ATOM 7235 C C . PRO C 1 79 ? -7.869 71.482 8.437 1.00 13.89 ? 112 PRO C C 1 ATOM 7236 O O . PRO C 1 79 ? -8.357 71.770 9.537 1.00 9.73 ? 112 PRO C O 1 ATOM 7237 C CB . PRO C 1 79 ? -9.216 72.652 6.822 1.00 13.02 ? 112 PRO C CB 1 ATOM 7238 C CG . PRO C 1 79 ? -10.715 72.676 6.891 1.00 12.78 ? 112 PRO C CG 1 ATOM 7239 C CD . PRO C 1 79 ? -11.025 71.775 8.048 1.00 13.70 ? 112 PRO C CD 1 ATOM 7240 N N . PRO C 1 80 ? -6.596 71.454 8.023 1.00 17.35 ? 113 PRO C N 1 ATOM 7241 C CA . PRO C 1 80 ? -5.234 71.597 8.597 1.00 18.06 ? 113 PRO C CA 1 ATOM 7242 C C . PRO C 1 80 ? -4.628 72.976 8.955 1.00 19.87 ? 113 PRO C C 1 ATOM 7243 O O . PRO C 1 80 ? -4.961 73.975 8.327 1.00 17.74 ? 113 PRO C O 1 ATOM 7244 C CB . PRO C 1 80 ? -4.352 71.115 7.438 1.00 18.28 ? 113 PRO C CB 1 ATOM 7245 C CG . PRO C 1 80 ? -5.067 71.587 6.248 1.00 18.44 ? 113 PRO C CG 1 ATOM 7246 C CD . PRO C 1 80 ? -6.525 71.208 6.561 1.00 18.14 ? 113 PRO C CD 1 ATOM 7247 N N . HIS C 1 81 ? -3.680 72.976 9.912 1.00 19.38 ? 114 HIS C N 1 ATOM 7248 C CA . HIS C 1 81 ? -3.021 74.192 10.359 1.00 19.87 ? 114 HIS C CA 1 ATOM 7249 C C . HIS C 1 81 ? -1.909 74.595 9.418 1.00 21.14 ? 114 HIS C C 1 ATOM 7250 O O . HIS C 1 81 ? -0.714 74.316 9.656 1.00 20.71 ? 114 HIS C O 1 ATOM 7251 C CB . HIS C 1 81 ? -2.442 74.002 11.750 1.00 20.42 ? 114 HIS C CB 1 ATOM 7252 C CG . HIS C 1 81 ? -3.466 73.645 12.768 1.00 20.63 ? 114 HIS C CG 1 ATOM 7253 N ND1 . HIS C 1 81 ? -3.943 72.364 12.913 1.00 20.40 ? 114 HIS C ND1 1 ATOM 7254 C CD2 . HIS C 1 81 ? -4.113 74.395 13.687 1.00 20.49 ? 114 HIS C CD2 1 ATOM 7255 C CE1 . HIS C 1 81 ? -4.834 72.334 13.881 1.00 19.40 ? 114 HIS C CE1 1 ATOM 7256 N NE2 . HIS C 1 81 ? -4.959 73.554 14.363 1.00 21.03 ? 114 HIS C NE2 1 ATOM 7257 N N . VAL C 1 82 ? -2.309 75.276 8.352 1.00 21.93 ? 115 VAL C N 1 ATOM 7258 C CA . VAL C 1 82 ? -1.373 75.841 7.382 1.00 23.09 ? 115 VAL C CA 1 ATOM 7259 C C . VAL C 1 82 ? -1.674 77.329 7.292 1.00 24.28 ? 115 VAL C C 1 ATOM 7260 O O . VAL C 1 82 ? -2.811 77.745 7.538 1.00 24.92 ? 115 VAL C O 1 ATOM 7261 C CB . VAL C 1 82 ? -1.502 75.135 6.021 1.00 24.41 ? 115 VAL C CB 1 ATOM 7262 C CG1 . VAL C 1 82 ? -0.733 73.824 6.028 1.00 24.59 ? 115 VAL C CG1 1 ATOM 7263 C CG2 . VAL C 1 82 ? -2.962 74.801 5.695 1.00 24.58 ? 115 VAL C CG2 1 ATOM 7264 N N . PRO C 1 83 ? -0.671 78.164 6.961 1.00 25.35 ? 116 PRO C N 1 ATOM 7265 C CA . PRO C 1 83 ? -1.028 79.588 6.792 1.00 24.30 ? 116 PRO C CA 1 ATOM 7266 C C . PRO C 1 83 ? -2.184 79.773 5.778 1.00 23.59 ? 116 PRO C C 1 ATOM 7267 O O . PRO C 1 83 ? -2.313 79.017 4.799 1.00 22.69 ? 116 PRO C O 1 ATOM 7268 C CB . PRO C 1 83 ? 0.261 80.250 6.324 1.00 24.46 ? 116 PRO C CB 1 ATOM 7269 C CG . PRO C 1 83 ? 1.343 79.263 6.583 1.00 25.69 ? 116 PRO C CG 1 ATOM 7270 C CD . PRO C 1 83 ? 0.734 77.891 6.650 1.00 25.88 ? 116 PRO C CD 1 ATOM 7271 N N . VAL C 1 84 ? -3.016 80.758 6.075 1.00 23.45 ? 117 VAL C N 1 ATOM 7272 C CA . VAL C 1 84 ? -4.234 81.045 5.345 1.00 26.24 ? 117 VAL C CA 1 ATOM 7273 C C . VAL C 1 84 ? -4.091 81.016 3.781 1.00 28.36 ? 117 VAL C C 1 ATOM 7274 O O . VAL C 1 84 ? -4.932 80.356 3.121 1.00 30.93 ? 117 VAL C O 1 ATOM 7275 C CB . VAL C 1 84 ? -4.904 82.347 5.886 1.00 26.90 ? 117 VAL C CB 1 ATOM 7276 C CG1 . VAL C 1 84 ? -6.086 82.765 5.014 1.00 27.69 ? 117 VAL C CG1 1 ATOM 7277 C CG2 . VAL C 1 84 ? -5.378 82.147 7.337 1.00 26.30 ? 117 VAL C CG2 1 ATOM 7278 N N . PRO C 1 85 ? -3.032 81.657 3.198 1.00 27.57 ? 118 PRO C N 1 ATOM 7279 C CA . PRO C 1 85 ? -2.793 81.736 1.701 1.00 28.52 ? 118 PRO C CA 1 ATOM 7280 C C . PRO C 1 85 ? -2.517 80.426 0.907 1.00 29.66 ? 118 PRO C C 1 ATOM 7281 O O . PRO C 1 85 ? -2.678 80.337 -0.344 1.00 25.60 ? 118 PRO C O 1 ATOM 7282 C CB . PRO C 1 85 ? -1.580 82.674 1.587 1.00 26.83 ? 118 PRO C CB 1 ATOM 7283 C CG . PRO C 1 85 ? -1.606 83.487 2.838 1.00 28.21 ? 118 PRO C CG 1 ATOM 7284 C CD . PRO C 1 85 ? -2.156 82.601 3.930 1.00 27.23 ? 118 PRO C CD 1 ATOM 7285 N N . GLU C 1 86 ? -2.120 79.425 1.670 1.00 31.60 ? 119 GLU C N 1 ATOM 7286 C CA . GLU C 1 86 ? -1.757 78.126 1.175 1.00 31.76 ? 119 GLU C CA 1 ATOM 7287 C C . GLU C 1 86 ? -3.024 77.326 1.081 1.00 27.27 ? 119 GLU C C 1 ATOM 7288 O O . GLU C 1 86 ? -2.970 76.278 0.503 1.00 28.34 ? 119 GLU C O 1 ATOM 7289 C CB . GLU C 1 86 ? -0.814 77.490 2.205 1.00 39.54 ? 119 GLU C CB 1 ATOM 7290 C CG . GLU C 1 86 ? 0.355 76.669 1.676 1.00 49.70 ? 119 GLU C CG 1 ATOM 7291 C CD . GLU C 1 86 ? 1.251 76.092 2.811 1.00 52.70 ? 119 GLU C CD 1 ATOM 7292 O OE1 . GLU C 1 86 ? 1.022 74.915 3.200 1.00 53.17 ? 119 GLU C OE1 1 ATOM 7293 O OE2 . GLU C 1 86 ? 2.163 76.809 3.319 1.00 45.37 -1 119 GLU C OE2 1 ATOM 7294 N N . LEU C 1 87 ? -4.131 77.800 1.694 1.00 25.59 ? 120 LEU C N 1 ATOM 7295 C CA . LEU C 1 87 ? -5.539 77.255 1.526 1.00 27.17 ? 120 LEU C CA 1 ATOM 7296 C C . LEU C 1 87 ? -6.495 78.191 0.761 1.00 25.36 ? 120 LEU C C 1 ATOM 7297 O O . LEU C 1 87 ? -6.189 79.322 0.551 1.00 24.31 ? 120 LEU C O 1 ATOM 7298 C CB . LEU C 1 87 ? -6.276 76.963 2.889 1.00 27.69 ? 120 LEU C CB 1 ATOM 7299 C CG . LEU C 1 87 ? -5.751 75.995 3.969 1.00 27.35 ? 120 LEU C CG 1 ATOM 7300 C CD1 . LEU C 1 87 ? -6.662 75.852 5.195 1.00 24.49 ? 120 LEU C CD1 1 ATOM 7301 C CD2 . LEU C 1 87 ? -5.476 74.664 3.282 1.00 28.84 ? 120 LEU C CD2 1 ATOM 7302 N N . SER C 1 88 ? -7.690 77.700 0.439 1.00 24.43 ? 121 SER C N 1 ATOM 7303 C CA . SER C 1 88 ? -8.741 78.475 -0.177 1.00 23.30 ? 121 SER C CA 1 ATOM 7304 C C . SER C 1 88 ? -10.167 77.918 0.205 1.00 24.41 ? 121 SER C C 1 ATOM 7305 O O . SER C 1 88 ? -10.270 76.823 0.805 1.00 25.66 ? 121 SER C O 1 ATOM 7306 C CB . SER C 1 88 ? -8.582 78.325 -1.677 1.00 23.30 ? 121 SER C CB 1 ATOM 7307 O OG . SER C 1 88 ? -9.110 77.047 -2.064 1.00 22.51 ? 121 SER C OG 1 ATOM 7308 N N . THR C 1 89 ? -11.246 78.608 -0.209 1.00 21.75 ? 122 THR C N 1 ATOM 7309 C CA . THR C 1 89 ? -12.581 78.099 -0.022 1.00 23.03 ? 122 THR C CA 1 ATOM 7310 C C . THR C 1 89 ? -12.796 76.693 -0.585 1.00 26.85 ? 122 THR C C 1 ATOM 7311 O O . THR C 1 89 ? -13.459 75.842 0.050 1.00 30.63 ? 122 THR C O 1 ATOM 7312 C CB . THR C 1 89 ? -13.588 79.030 -0.645 1.00 22.80 ? 122 THR C CB 1 ATOM 7313 O OG1 . THR C 1 89 ? -13.566 80.242 0.093 1.00 23.52 ? 122 THR C OG1 1 ATOM 7314 C CG2 . THR C 1 89 ? -14.992 78.486 -0.531 1.00 22.85 ? 122 THR C CG2 1 ATOM 7315 N N . ASP C 1 90 ? -12.207 76.453 -1.753 1.00 28.43 ? 123 ASP C N 1 ATOM 7316 C CA . ASP C 1 90 ? -12.369 75.214 -2.491 1.00 28.66 ? 123 ASP C CA 1 ATOM 7317 C C . ASP C 1 90 ? -11.641 74.053 -1.850 1.00 29.13 ? 123 ASP C C 1 ATOM 7318 O O . ASP C 1 90 ? -12.147 72.942 -1.914 1.00 31.82 ? 123 ASP C O 1 ATOM 7319 C CB . ASP C 1 90 ? -11.860 75.365 -3.937 1.00 29.50 ? 123 ASP C CB 1 ATOM 7320 C CG . ASP C 1 90 ? -11.861 74.035 -4.697 1.00 33.42 ? 123 ASP C CG 1 ATOM 7321 O OD1 . ASP C 1 90 ? -12.924 73.297 -4.752 1.00 33.35 ? 123 ASP C OD1 1 ATOM 7322 O OD2 . ASP C 1 90 ? -10.755 73.712 -5.216 1.00 34.95 -1 123 ASP C OD2 1 ATOM 7323 N N . THR C 1 91 ? -10.420 74.268 -1.331 1.00 27.92 ? 124 THR C N 1 ATOM 7324 C CA . THR C 1 91 ? -9.672 73.182 -0.645 1.00 24.43 ? 124 THR C CA 1 ATOM 7325 C C . THR C 1 91 ? -10.294 72.821 0.651 1.00 20.12 ? 124 THR C C 1 ATOM 7326 O O . THR C 1 91 ? -10.254 71.685 1.017 1.00 17.93 ? 124 THR C O 1 ATOM 7327 C CB . THR C 1 91 ? -8.256 73.586 -0.268 1.00 26.72 ? 124 THR C CB 1 ATOM 7328 O OG1 . THR C 1 91 ? -7.624 74.146 -1.420 1.00 30.45 ? 124 THR C OG1 1 ATOM 7329 C CG2 . THR C 1 91 ? -7.442 72.333 0.283 1.00 28.39 ? 124 THR C CG2 1 ATOM 7330 N N . VAL C 1 92 ? -10.781 73.843 1.355 1.00 18.89 ? 125 VAL C N 1 ATOM 7331 C CA . VAL C 1 92 ? -11.449 73.685 2.633 1.00 18.80 ? 125 VAL C CA 1 ATOM 7332 C C . VAL C 1 92 ? -12.702 72.774 2.465 1.00 18.71 ? 125 VAL C C 1 ATOM 7333 O O . VAL C 1 92 ? -12.869 71.778 3.129 1.00 17.19 ? 125 VAL C O 1 ATOM 7334 C CB . VAL C 1 92 ? -11.814 75.079 3.199 1.00 16.96 ? 125 VAL C CB 1 ATOM 7335 C CG1 . VAL C 1 92 ? -13.094 74.988 4.025 1.00 16.72 ? 125 VAL C CG1 1 ATOM 7336 C CG2 . VAL C 1 92 ? -10.644 75.668 3.980 1.00 15.66 ? 125 VAL C CG2 1 ATOM 7337 N N . ILE C 1 93 ? -13.554 73.146 1.531 1.00 20.55 ? 126 ILE C N 1 ATOM 7338 C CA . ILE C 1 93 ? -14.635 72.280 1.079 1.00 21.03 ? 126 ILE C CA 1 ATOM 7339 C C . ILE C 1 93 ? -14.194 70.869 0.653 1.00 21.88 ? 126 ILE C C 1 ATOM 7340 O O . ILE C 1 93 ? -14.755 69.842 1.134 1.00 23.55 ? 126 ILE C O 1 ATOM 7341 C CB . ILE C 1 93 ? -15.478 72.967 -0.022 1.00 18.78 ? 126 ILE C CB 1 ATOM 7342 C CG1 . ILE C 1 93 ? -16.226 74.134 0.658 1.00 19.73 ? 126 ILE C CG1 1 ATOM 7343 C CG2 . ILE C 1 93 ? -16.378 71.939 -0.664 1.00 17.57 ? 126 ILE C CG2 1 ATOM 7344 C CD1 . ILE C 1 93 ? -16.481 75.398 -0.131 1.00 19.56 ? 126 ILE C CD1 1 ATOM 7345 N N . ASN C 1 94 ? -13.197 70.781 -0.206 1.00 23.30 ? 127 ASN C N 1 ATOM 7346 C CA . ASN C 1 94 ? -12.702 69.456 -0.580 1.00 25.41 ? 127 ASN C CA 1 ATOM 7347 C C . ASN C 1 94 ? -12.352 68.656 0.671 1.00 21.79 ? 127 ASN C C 1 ATOM 7348 O O . ASN C 1 94 ? -12.682 67.489 0.798 1.00 23.20 ? 127 ASN C O 1 ATOM 7349 C CB . ASN C 1 94 ? -11.540 69.511 -1.579 1.00 29.62 ? 127 ASN C CB 1 ATOM 7350 C CG . ASN C 1 94 ? -12.030 69.644 -3.014 1.00 35.73 ? 127 ASN C CG 1 ATOM 7351 O OD1 . ASN C 1 94 ? -12.944 70.435 -3.325 1.00 35.84 ? 127 ASN C OD1 1 ATOM 7352 N ND2 . ASN C 1 94 ? -11.422 68.883 -3.896 1.00 38.82 ? 127 ASN C ND2 1 ATOM 7353 N N . VAL C 1 95 ? -11.727 69.284 1.622 1.00 18.58 ? 128 VAL C N 1 ATOM 7354 C CA . VAL C 1 95 ? -11.411 68.584 2.796 1.00 18.45 ? 128 VAL C CA 1 ATOM 7355 C C . VAL C 1 95 ? -12.639 68.108 3.612 1.00 18.85 ? 128 VAL C C 1 ATOM 7356 O O . VAL C 1 95 ? -12.653 67.033 4.218 1.00 16.29 ? 128 VAL C O 1 ATOM 7357 C CB . VAL C 1 95 ? -10.423 69.420 3.594 1.00 17.93 ? 128 VAL C CB 1 ATOM 7358 C CG1 . VAL C 1 95 ? -10.260 68.894 5.017 1.00 15.68 ? 128 VAL C CG1 1 ATOM 7359 C CG2 . VAL C 1 95 ? -9.105 69.350 2.771 1.00 18.48 ? 128 VAL C CG2 1 ATOM 7360 N N . ILE C 1 96 ? -13.685 68.888 3.629 1.00 20.08 ? 129 ILE C N 1 ATOM 7361 C CA . ILE C 1 96 ? -14.785 68.504 4.462 1.00 20.90 ? 129 ILE C CA 1 ATOM 7362 C C . ILE C 1 96 ? -15.567 67.354 3.807 1.00 21.08 ? 129 ILE C C 1 ATOM 7363 O O . ILE C 1 96 ? -15.980 66.324 4.472 1.00 16.11 ? 129 ILE C O 1 ATOM 7364 C CB . ILE C 1 96 ? -15.566 69.741 4.823 1.00 21.31 ? 129 ILE C CB 1 ATOM 7365 C CG1 . ILE C 1 96 ? -14.617 70.609 5.658 1.00 20.89 ? 129 ILE C CG1 1 ATOM 7366 C CG2 . ILE C 1 96 ? -16.864 69.370 5.580 1.00 22.07 ? 129 ILE C CG2 1 ATOM 7367 C CD1 . ILE C 1 96 ? -15.070 72.056 5.733 1.00 22.40 ? 129 ILE C CD1 1 ATOM 7368 N N . THR C 1 97 ? -15.659 67.535 2.480 1.00 23.08 ? 130 THR C N 1 ATOM 7369 C CA . THR C 1 97 ? -16.275 66.601 1.556 1.00 22.13 ? 130 THR C CA 1 ATOM 7370 C C . THR C 1 97 ? -15.597 65.291 1.786 1.00 20.38 ? 130 THR C C 1 ATOM 7371 O O . THR C 1 97 ? -16.244 64.351 2.117 1.00 20.59 ? 130 THR C O 1 ATOM 7372 C CB . THR C 1 97 ? -16.092 67.087 0.072 1.00 24.67 ? 130 THR C CB 1 ATOM 7373 O OG1 . THR C 1 97 ? -16.730 68.378 -0.127 1.00 26.98 ? 130 THR C OG1 1 ATOM 7374 C CG2 . THR C 1 97 ? -16.664 66.016 -0.970 1.00 24.99 ? 130 THR C CG2 1 ATOM 7375 N N . ASN C 1 98 ? -14.281 65.251 1.651 1.00 20.74 ? 131 ASN C N 1 ATOM 7376 C CA . ASN C 1 98 ? -13.437 64.073 1.846 1.00 21.35 ? 131 ASN C CA 1 ATOM 7377 C C . ASN C 1 98 ? -13.616 63.381 3.198 1.00 20.74 ? 131 ASN C C 1 ATOM 7378 O O . ASN C 1 98 ? -13.814 62.205 3.275 1.00 21.03 ? 131 ASN C O 1 ATOM 7379 C CB . ASN C 1 98 ? -11.989 64.395 1.524 1.00 20.87 ? 131 ASN C CB 1 ATOM 7380 C CG . ASN C 1 98 ? -11.101 63.234 1.681 1.00 21.94 ? 131 ASN C CG 1 ATOM 7381 O OD1 . ASN C 1 98 ? -11.043 62.641 2.693 1.00 21.69 ? 131 ASN C OD1 1 ATOM 7382 N ND2 . ASN C 1 98 ? -10.435 62.896 0.671 1.00 29.79 ? 131 ASN C ND2 1 ATOM 7383 N N . MET C 1 99 ? -13.542 64.119 4.259 1.00 20.03 ? 132 MET C N 1 ATOM 7384 C CA . MET C 1 99 ? -13.918 63.604 5.606 1.00 21.45 ? 132 MET C CA 1 ATOM 7385 C C . MET C 1 99 ? -15.379 63.087 5.661 1.00 22.92 ? 132 MET C C 1 ATOM 7386 O O . MET C 1 99 ? -15.674 62.003 6.263 1.00 21.53 ? 132 MET C O 1 ATOM 7387 C CB . MET C 1 99 ? -13.768 64.681 6.700 1.00 19.90 ? 132 MET C CB 1 ATOM 7388 C CG . MET C 1 99 ? -12.382 65.040 7.133 1.00 19.98 ? 132 MET C CG 1 ATOM 7389 S SD . MET C 1 99 ? -11.342 63.637 7.422 1.00 20.79 ? 132 MET C SD 1 ATOM 7390 C CE . MET C 1 99 ? -10.853 63.398 5.693 1.00 21.59 ? 132 MET C CE 1 ATOM 7391 N N . THR C 1 100 ? -16.272 63.909 5.101 1.00 22.26 ? 133 THR C N 1 ATOM 7392 C CA . THR C 1 100 ? -17.652 63.521 4.955 1.00 21.93 ? 133 THR C CA 1 ATOM 7393 C C . THR C 1 100 ? -17.863 62.251 4.101 1.00 21.91 ? 133 THR C C 1 ATOM 7394 O O . THR C 1 100 ? -18.494 61.315 4.583 1.00 20.94 ? 133 THR C O 1 ATOM 7395 C CB . THR C 1 100 ? -18.461 64.703 4.446 1.00 20.56 ? 133 THR C CB 1 ATOM 7396 O OG1 . THR C 1 100 ? -18.347 65.707 5.428 1.00 20.03 ? 133 THR C OG1 1 ATOM 7397 C CG2 . THR C 1 100 ? -19.945 64.336 4.316 1.00 22.06 ? 133 THR C CG2 1 ATOM 7398 N N . THR C 1 101 ? -17.333 62.217 2.872 1.00 23.88 ? 134 THR C N 1 ATOM 7399 C CA . THR C 1 101 ? -17.486 61.055 1.999 1.00 25.47 ? 134 THR C CA 1 ATOM 7400 C C . THR C 1 101 ? -16.982 59.863 2.748 1.00 24.03 ? 134 THR C C 1 ATOM 7401 O O . THR C 1 101 ? -17.635 58.862 2.760 1.00 24.67 ? 134 THR C O 1 ATOM 7402 C CB . THR C 1 101 ? -16.637 61.099 0.704 1.00 28.75 ? 134 THR C CB 1 ATOM 7403 O OG1 . THR C 1 101 ? -16.888 62.310 -0.037 1.00 31.64 ? 134 THR C OG1 1 ATOM 7404 C CG2 . THR C 1 101 ? -16.908 59.756 -0.199 1.00 28.70 ? 134 THR C CG2 1 ATOM 7405 N N . THR C 1 102 ? -15.809 60.000 3.367 1.00 23.34 ? 135 THR C N 1 ATOM 7406 C CA . THR C 1 102 ? -15.178 58.914 4.130 1.00 23.12 ? 135 THR C CA 1 ATOM 7407 C C . THR C 1 102 ? -15.971 58.298 5.300 1.00 24.19 ? 135 THR C C 1 ATOM 7408 O O . THR C 1 102 ? -16.027 57.070 5.433 1.00 25.88 ? 135 THR C O 1 ATOM 7409 C CB . THR C 1 102 ? -13.862 59.355 4.710 1.00 20.90 ? 135 THR C CB 1 ATOM 7410 O OG1 . THR C 1 102 ? -13.013 59.814 3.662 1.00 19.05 ? 135 THR C OG1 1 ATOM 7411 C CG2 . THR C 1 102 ? -13.226 58.198 5.356 1.00 20.99 ? 135 THR C CG2 1 ATOM 7412 N N . ILE C 1 103 ? -16.547 59.143 6.159 1.00 25.27 ? 136 ILE C N 1 ATOM 7413 C CA . ILE C 1 103 ? -17.542 58.717 7.196 1.00 23.06 ? 136 ILE C CA 1 ATOM 7414 C C . ILE C 1 103 ? -18.741 58.019 6.606 1.00 23.20 ? 136 ILE C C 1 ATOM 7415 O O . ILE C 1 103 ? -19.122 56.923 7.040 1.00 21.85 ? 136 ILE C O 1 ATOM 7416 C CB . ILE C 1 103 ? -17.993 59.906 8.051 1.00 22.37 ? 136 ILE C CB 1 ATOM 7417 C CG1 . ILE C 1 103 ? -16.795 60.310 8.955 1.00 23.65 ? 136 ILE C CG1 1 ATOM 7418 C CG2 . ILE C 1 103 ? -19.236 59.556 8.843 1.00 21.24 ? 136 ILE C CG2 1 ATOM 7419 C CD1 . ILE C 1 103 ? -16.637 61.783 9.290 1.00 25.26 ? 136 ILE C CD1 1 ATOM 7420 N N . GLN C 1 104 ? -19.307 58.605 5.567 1.00 24.92 ? 137 GLN C N 1 ATOM 7421 C CA . GLN C 1 104 ? -20.518 58.005 4.924 1.00 26.00 ? 137 GLN C CA 1 ATOM 7422 C C . GLN C 1 104 ? -20.339 56.602 4.276 1.00 24.81 ? 137 GLN C C 1 ATOM 7423 O O . GLN C 1 104 ? -21.260 55.785 4.326 1.00 28.27 ? 137 GLN C O 1 ATOM 7424 C CB . GLN C 1 104 ? -21.199 59.024 3.974 1.00 25.34 ? 137 GLN C CB 1 ATOM 7425 C CG . GLN C 1 104 ? -22.067 60.001 4.754 1.00 23.85 ? 137 GLN C CG 1 ATOM 7426 C CD . GLN C 1 104 ? -22.395 61.238 4.001 1.00 25.00 ? 137 GLN C CD 1 ATOM 7427 O OE1 . GLN C 1 104 ? -22.096 61.340 2.818 1.00 29.99 ? 137 GLN C OE1 1 ATOM 7428 N NE2 . GLN C 1 104 ? -23.049 62.187 4.664 1.00 26.78 ? 137 GLN C NE2 1 ATOM 7429 N N . SER C 1 105 ? -19.169 56.332 3.710 1.00 23.99 ? 138 SER C N 1 ATOM 7430 C CA . SER C 1 105 ? -18.796 55.012 3.213 1.00 23.74 ? 138 SER C CA 1 ATOM 7431 C C . SER C 1 105 ? -18.574 54.013 4.252 1.00 23.36 ? 138 SER C C 1 ATOM 7432 O O . SER C 1 105 ? -19.113 52.983 4.168 1.00 24.74 ? 138 SER C O 1 ATOM 7433 C CB . SER C 1 105 ? -17.475 55.095 2.485 1.00 24.76 ? 138 SER C CB 1 ATOM 7434 O OG . SER C 1 105 ? -17.514 56.261 1.735 1.00 28.74 ? 138 SER C OG 1 ATOM 7435 N N . LEU C 1 106 ? -17.711 54.300 5.208 1.00 26.90 ? 139 LEU C N 1 ATOM 7436 C CA . LEU C 1 106 ? -17.458 53.380 6.321 1.00 30.41 ? 139 LEU C CA 1 ATOM 7437 C C . LEU C 1 106 ? -18.686 53.081 7.225 1.00 28.79 ? 139 LEU C C 1 ATOM 7438 O O . LEU C 1 106 ? -18.793 51.980 7.764 1.00 28.61 ? 139 LEU C O 1 ATOM 7439 C CB . LEU C 1 106 ? -16.304 53.901 7.201 1.00 33.31 ? 139 LEU C CB 1 ATOM 7440 C CG . LEU C 1 106 ? -14.815 53.936 6.763 1.00 35.64 ? 139 LEU C CG 1 ATOM 7441 C CD1 . LEU C 1 106 ? -14.027 53.431 7.989 1.00 38.85 ? 139 LEU C CD1 1 ATOM 7442 C CD2 . LEU C 1 106 ? -14.387 53.150 5.515 1.00 30.75 ? 139 LEU C CD2 1 ATOM 7443 N N . PHE C 1 107 ? -19.587 54.055 7.394 1.00 28.33 ? 140 PHE C N 1 ATOM 7444 C CA . PHE C 1 107 ? -20.737 53.940 8.340 1.00 28.43 ? 140 PHE C CA 1 ATOM 7445 C C . PHE C 1 107 ? -22.056 54.248 7.532 1.00 30.56 ? 140 PHE C C 1 ATOM 7446 O O . PHE C 1 107 ? -22.799 55.253 7.766 1.00 26.40 ? 140 PHE C O 1 ATOM 7447 C CB . PHE C 1 107 ? -20.549 54.866 9.608 1.00 26.68 ? 140 PHE C CB 1 ATOM 7448 C CG . PHE C 1 107 ? -19.241 54.650 10.392 1.00 24.87 ? 140 PHE C CG 1 ATOM 7449 C CD1 . PHE C 1 107 ? -19.012 53.492 11.120 1.00 23.40 ? 140 PHE C CD1 1 ATOM 7450 C CD2 . PHE C 1 107 ? -18.254 55.602 10.389 1.00 25.08 ? 140 PHE C CD2 1 ATOM 7451 C CE1 . PHE C 1 107 ? -17.825 53.279 11.796 1.00 22.37 ? 140 PHE C CE1 1 ATOM 7452 C CE2 . PHE C 1 107 ? -17.075 55.386 11.067 1.00 26.19 ? 140 PHE C CE2 1 ATOM 7453 C CZ . PHE C 1 107 ? -16.873 54.237 11.804 1.00 24.07 ? 140 PHE C CZ 1 ATOM 7454 N N . PRO C 1 108 ? -22.363 53.389 6.549 1.00 34.30 ? 141 PRO C N 1 ATOM 7455 C CA . PRO C 1 108 ? -23.559 53.682 5.721 1.00 37.40 ? 141 PRO C CA 1 ATOM 7456 C C . PRO C 1 108 ? -24.924 53.823 6.516 1.00 38.34 ? 141 PRO C C 1 ATOM 7457 O O . PRO C 1 108 ? -25.825 54.524 6.037 1.00 35.98 ? 141 PRO C O 1 ATOM 7458 C CB . PRO C 1 108 ? -23.600 52.499 4.704 1.00 35.03 ? 141 PRO C CB 1 ATOM 7459 C CG . PRO C 1 108 ? -22.433 51.631 5.010 1.00 35.67 ? 141 PRO C CG 1 ATOM 7460 C CD . PRO C 1 108 ? -21.899 52.002 6.369 1.00 36.32 ? 141 PRO C CD 1 ATOM 7461 N N . ASN C 1 109 ? -25.040 53.182 7.700 1.00 38.05 ? 142 ASN C N 1 ATOM 7462 C CA . ASN C 1 109 ? -26.268 53.201 8.524 1.00 34.43 ? 142 ASN C CA 1 ATOM 7463 C C . ASN C 1 109 ? -26.072 53.829 9.920 1.00 31.36 ? 142 ASN C C 1 ATOM 7464 O O . ASN C 1 109 ? -26.416 53.270 10.936 1.00 34.94 ? 142 ASN C O 1 ATOM 7465 C CB . ASN C 1 109 ? -26.878 51.799 8.624 1.00 33.04 ? 142 ASN C CB 1 ATOM 7466 C CG . ASN C 1 109 ? -27.086 51.176 7.272 1.00 35.43 ? 142 ASN C CG 1 ATOM 7467 O OD1 . ASN C 1 109 ? -26.456 50.176 6.953 1.00 37.52 ? 142 ASN C OD1 1 ATOM 7468 N ND2 . ASN C 1 109 ? -27.922 51.796 6.438 1.00 37.56 ? 142 ASN C ND2 1 ATOM 7469 N N . LEU C 1 110 ? -25.575 55.040 9.950 1.00 26.95 ? 143 LEU C N 1 ATOM 7470 C CA . LEU C 1 110 ? -25.428 55.708 11.181 1.00 23.89 ? 143 LEU C CA 1 ATOM 7471 C C . LEU C 1 110 ? -25.585 57.161 10.908 1.00 20.00 ? 143 LEU C C 1 ATOM 7472 O O . LEU C 1 110 ? -24.894 57.739 10.086 1.00 18.76 ? 143 LEU C O 1 ATOM 7473 C CB . LEU C 1 110 ? -24.064 55.352 11.866 1.00 25.15 ? 143 LEU C CB 1 ATOM 7474 C CG . LEU C 1 110 ? -23.814 55.989 13.269 1.00 23.99 ? 143 LEU C CG 1 ATOM 7475 C CD1 . LEU C 1 110 ? -24.324 55.211 14.458 1.00 21.81 ? 143 LEU C CD1 1 ATOM 7476 C CD2 . LEU C 1 110 ? -22.331 56.281 13.441 1.00 25.51 ? 143 LEU C CD2 1 ATOM 7477 N N . GLN C 1 111 ? -26.511 57.746 11.657 1.00 19.86 ? 144 GLN C N 1 ATOM 7478 C CA . GLN C 1 111 ? -26.707 59.178 11.717 1.00 18.90 ? 144 GLN C CA 1 ATOM 7479 C C . GLN C 1 111 ? -25.482 59.835 12.399 1.00 20.81 ? 144 GLN C C 1 ATOM 7480 O O . GLN C 1 111 ? -24.919 59.298 13.423 1.00 19.56 ? 144 GLN C O 1 ATOM 7481 C CB . GLN C 1 111 ? -27.947 59.485 12.506 1.00 18.44 ? 144 GLN C CB 1 ATOM 7482 C CG . GLN C 1 111 ? -28.523 60.839 12.144 1.00 20.96 ? 144 GLN C CG 1 ATOM 7483 C CD . GLN C 1 111 ? -29.931 61.052 12.650 1.00 22.56 ? 144 GLN C CD 1 ATOM 7484 O OE1 . GLN C 1 111 ? -30.336 60.471 13.667 1.00 26.68 ? 144 GLN C OE1 1 ATOM 7485 N NE2 . GLN C 1 111 ? -30.668 61.892 11.972 1.00 22.23 ? 144 GLN C NE2 1 ATOM 7486 N N . VAL C 1 112 ? -25.023 60.932 11.794 1.00 18.87 ? 145 VAL C N 1 ATOM 7487 C CA . VAL C 1 112 ? -23.817 61.629 12.231 1.00 20.72 ? 145 VAL C CA 1 ATOM 7488 C C . VAL C 1 112 ? -24.214 63.112 12.360 1.00 20.69 ? 145 VAL C C 1 ATOM 7489 O O . VAL C 1 112 ? -24.763 63.690 11.430 1.00 19.13 ? 145 VAL C O 1 ATOM 7490 C CB . VAL C 1 112 ? -22.641 61.455 11.216 1.00 22.41 ? 145 VAL C CB 1 ATOM 7491 C CG1 . VAL C 1 112 ? -21.435 62.386 11.499 1.00 22.43 ? 145 VAL C CG1 1 ATOM 7492 C CG2 . VAL C 1 112 ? -22.261 59.998 11.138 1.00 23.42 ? 145 VAL C CG2 1 ATOM 7493 N N . PHE C 1 113 ? -23.932 63.710 13.513 1.00 20.78 ? 146 PHE C N 1 ATOM 7494 C CA . PHE C 1 113 ? -24.365 65.057 13.818 1.00 21.32 ? 146 PHE C CA 1 ATOM 7495 C C . PHE C 1 113 ? -23.156 65.973 13.746 1.00 19.98 ? 146 PHE C C 1 ATOM 7496 O O . PHE C 1 113 ? -22.273 65.863 14.561 1.00 19.43 ? 146 PHE C O 1 ATOM 7497 C CB . PHE C 1 113 ? -25.037 65.122 15.198 1.00 22.84 ? 146 PHE C CB 1 ATOM 7498 C CG . PHE C 1 113 ? -26.359 64.387 15.268 1.00 23.60 ? 146 PHE C CG 1 ATOM 7499 C CD1 . PHE C 1 113 ? -26.415 63.089 15.779 1.00 23.12 ? 146 PHE C CD1 1 ATOM 7500 C CD2 . PHE C 1 113 ? -27.526 64.973 14.794 1.00 23.55 ? 146 PHE C CD2 1 ATOM 7501 C CE1 . PHE C 1 113 ? -27.601 62.392 15.834 1.00 24.37 ? 146 PHE C CE1 1 ATOM 7502 C CE2 . PHE C 1 113 ? -28.719 64.269 14.827 1.00 24.49 ? 146 PHE C CE2 1 ATOM 7503 C CZ . PHE C 1 113 ? -28.768 62.968 15.353 1.00 24.50 ? 146 PHE C CZ 1 ATOM 7504 N N . PRO C 1 114 ? -23.080 66.800 12.688 1.00 19.77 ? 147 PRO C N 1 ATOM 7505 C CA . PRO C 1 114 ? -21.963 67.682 12.619 1.00 18.51 ? 147 PRO C CA 1 ATOM 7506 C C . PRO C 1 114 ? -22.133 69.048 13.171 1.00 16.26 ? 147 PRO C C 1 ATOM 7507 O O . PRO C 1 114 ? -23.221 69.562 13.238 1.00 15.85 ? 147 PRO C O 1 ATOM 7508 C CB . PRO C 1 114 ? -21.680 67.771 11.098 1.00 19.56 ? 147 PRO C CB 1 ATOM 7509 C CG . PRO C 1 114 ? -22.130 66.477 10.573 1.00 20.05 ? 147 PRO C CG 1 ATOM 7510 C CD . PRO C 1 114 ? -23.424 66.312 11.326 1.00 20.63 ? 147 PRO C CD 1 ATOM 7511 N N . ALA C 1 115 ? -20.964 69.620 13.473 1.00 15.20 ? 148 ALA C N 1 ATOM 7512 C CA . ALA C 1 115 ? -20.771 71.000 13.800 1.00 14.55 ? 148 ALA C CA 1 ATOM 7513 C C . ALA C 1 115 ? -19.516 71.595 13.080 1.00 13.39 ? 148 ALA C C 1 ATOM 7514 O O . ALA C 1 115 ? -18.483 70.964 12.987 1.00 13.78 ? 148 ALA C O 1 ATOM 7515 C CB . ALA C 1 115 ? -20.585 71.073 15.313 1.00 14.52 ? 148 ALA C CB 1 ATOM 7516 N N . LEU C 1 116 ? -19.576 72.820 12.634 1.00 12.37 ? 149 LEU C N 1 ATOM 7517 C CA . LEU C 1 116 ? -18.450 73.380 12.003 1.00 13.00 ? 149 LEU C CA 1 ATOM 7518 C C . LEU C 1 116 ? -17.438 73.826 12.999 1.00 13.64 ? 149 LEU C C 1 ATOM 7519 O O . LEU C 1 116 ? -17.769 74.229 14.107 1.00 15.01 ? 149 LEU C O 1 ATOM 7520 C CB . LEU C 1 116 ? -18.885 74.591 11.221 1.00 14.92 ? 149 LEU C CB 1 ATOM 7521 C CG . LEU C 1 116 ? -19.721 74.228 10.003 1.00 15.21 ? 149 LEU C CG 1 ATOM 7522 C CD1 . LEU C 1 116 ? -20.612 75.368 9.678 1.00 16.01 ? 149 LEU C CD1 1 ATOM 7523 C CD2 . LEU C 1 116 ? -18.797 73.926 8.844 1.00 16.12 ? 149 LEU C CD2 1 ATOM 7524 N N . GLY C 1 117 ? -16.184 73.774 12.617 1.00 13.12 ? 150 GLY C N 1 ATOM 7525 C CA . GLY C 1 117 ? -15.172 74.216 13.463 1.00 13.36 ? 150 GLY C CA 1 ATOM 7526 C C . GLY C 1 117 ? -14.683 75.557 12.967 1.00 15.63 ? 150 GLY C C 1 ATOM 7527 O O . GLY C 1 117 ? -15.183 76.134 12.014 1.00 15.36 ? 150 GLY C O 1 ATOM 7528 N N . ASN C 1 118 ? -13.593 75.976 13.605 1.00 18.15 ? 151 ASN C N 1 ATOM 7529 C CA . ASN C 1 118 ? -12.884 77.190 13.257 1.00 18.38 ? 151 ASN C CA 1 ATOM 7530 C C . ASN C 1 118 ? -12.165 76.966 11.928 1.00 16.76 ? 151 ASN C C 1 ATOM 7531 O O . ASN C 1 118 ? -12.313 77.772 11.009 1.00 15.48 ? 151 ASN C O 1 ATOM 7532 C CB . ASN C 1 118 ? -11.882 77.562 14.350 1.00 18.88 ? 151 ASN C CB 1 ATOM 7533 C CG . ASN C 1 118 ? -10.647 76.684 14.331 1.00 19.15 ? 151 ASN C CG 1 ATOM 7534 O OD1 . ASN C 1 118 ? -10.583 75.667 15.021 1.00 19.93 ? 151 ASN C OD1 1 ATOM 7535 N ND2 . ASN C 1 118 ? -9.655 77.074 13.538 1.00 19.23 ? 151 ASN C ND2 1 ATOM 7536 N N . HIS C 1 119 ? -11.394 75.879 11.803 1.00 15.08 ? 152 HIS C N 1 ATOM 7537 C CA . HIS C 1 119 ? -10.735 75.652 10.541 1.00 13.92 ? 152 HIS C CA 1 ATOM 7538 C C . HIS C 1 119 ? -11.608 75.270 9.502 1.00 14.17 ? 152 HIS C C 1 ATOM 7539 O O . HIS C 1 119 ? -11.203 75.238 8.444 1.00 13.81 ? 152 HIS C O 1 ATOM 7540 C CB . HIS C 1 119 ? -9.642 74.691 10.620 1.00 14.31 ? 152 HIS C CB 1 ATOM 7541 C CG . HIS C 1 119 ? -8.517 75.243 11.412 1.00 18.18 ? 152 HIS C CG 1 ATOM 7542 N ND1 . HIS C 1 119 ? -7.319 75.587 10.861 1.00 17.82 ? 152 HIS C ND1 1 ATOM 7543 C CD2 . HIS C 1 119 ? -8.437 75.562 12.721 1.00 18.06 ? 152 HIS C CD2 1 ATOM 7544 C CE1 . HIS C 1 119 ? -6.550 76.088 11.795 1.00 19.43 ? 152 HIS C CE1 1 ATOM 7545 N NE2 . HIS C 1 119 ? -7.209 76.103 12.927 1.00 18.47 ? 152 HIS C NE2 1 ATOM 7546 N N . ASP C 1 120 ? -12.860 74.999 9.802 1.00 16.71 ? 153 ASP C N 1 ATOM 7547 C CA . ASP C 1 120 ? -13.796 74.654 8.729 1.00 17.30 ? 153 ASP C CA 1 ATOM 7548 C C . ASP C 1 120 ? -14.215 75.665 7.608 1.00 18.74 ? 153 ASP C C 1 ATOM 7549 O O . ASP C 1 120 ? -14.985 75.325 6.732 1.00 19.38 ? 153 ASP C O 1 ATOM 7550 C CB . ASP C 1 120 ? -14.968 73.933 9.359 1.00 16.16 ? 153 ASP C CB 1 ATOM 7551 C CG . ASP C 1 120 ? -14.573 72.611 9.828 1.00 14.94 ? 153 ASP C CG 1 ATOM 7552 O OD1 . ASP C 1 120 ? -13.444 72.237 9.518 1.00 12.18 ? 153 ASP C OD1 1 ATOM 7553 O OD2 . ASP C 1 120 ? -15.366 71.984 10.544 1.00 15.33 -1 153 ASP C OD2 1 ATOM 7554 N N . TYR C 1 121 ? -13.640 76.849 7.601 1.00 20.72 ? 154 TYR C N 1 ATOM 7555 C CA . TYR C 1 121 ? -14.018 77.901 6.671 1.00 22.30 ? 154 TYR C CA 1 ATOM 7556 C C . TYR C 1 121 ? -12.698 78.472 6.198 1.00 21.62 ? 154 TYR C C 1 ATOM 7557 O O . TYR C 1 121 ? -11.691 78.342 6.896 1.00 25.73 ? 154 TYR C O 1 ATOM 7558 C CB . TYR C 1 121 ? -14.862 79.005 7.450 1.00 23.01 ? 154 TYR C CB 1 ATOM 7559 C CG . TYR C 1 121 ? -15.603 80.108 6.577 1.00 23.39 ? 154 TYR C CG 1 ATOM 7560 C CD1 . TYR C 1 121 ? -16.828 79.852 5.924 1.00 22.23 ? 154 TYR C CD1 1 ATOM 7561 C CD2 . TYR C 1 121 ? -15.064 81.427 6.437 1.00 23.36 ? 154 TYR C CD2 1 ATOM 7562 C CE1 . TYR C 1 121 ? -17.469 80.845 5.134 1.00 23.23 ? 154 TYR C CE1 1 ATOM 7563 C CE2 . TYR C 1 121 ? -15.710 82.408 5.667 1.00 23.17 ? 154 TYR C CE2 1 ATOM 7564 C CZ . TYR C 1 121 ? -16.914 82.121 5.014 1.00 22.77 ? 154 TYR C CZ 1 ATOM 7565 O OH . TYR C 1 121 ? -17.519 83.088 4.218 1.00 23.57 ? 154 TYR C OH 1 ATOM 7566 N N . TRP C 1 122 ? -12.723 79.099 5.039 1.00 21.02 ? 155 TRP C N 1 ATOM 7567 C CA . TRP C 1 122 ? -11.642 79.937 4.568 1.00 22.21 ? 155 TRP C CA 1 ATOM 7568 C C . TRP C 1 122 ? -11.976 81.449 4.437 1.00 22.48 ? 155 TRP C C 1 ATOM 7569 O O . TRP C 1 122 ? -12.980 81.871 3.820 1.00 24.54 ? 155 TRP C O 1 ATOM 7570 C CB . TRP C 1 122 ? -11.171 79.413 3.235 1.00 24.70 ? 155 TRP C CB 1 ATOM 7571 C CG . TRP C 1 122 ? -9.942 80.007 2.934 1.00 26.46 ? 155 TRP C CG 1 ATOM 7572 C CD1 . TRP C 1 122 ? -8.712 79.581 3.306 1.00 26.00 ? 155 TRP C CD1 1 ATOM 7573 C CD2 . TRP C 1 122 ? -9.788 81.207 2.273 1.00 29.36 ? 155 TRP C CD2 1 ATOM 7574 N NE1 . TRP C 1 122 ? -7.787 80.464 2.910 1.00 27.39 ? 155 TRP C NE1 1 ATOM 7575 C CE2 . TRP C 1 122 ? -8.421 81.473 2.235 1.00 32.29 ? 155 TRP C CE2 1 ATOM 7576 C CE3 . TRP C 1 122 ? -10.675 82.071 1.647 1.00 30.91 ? 155 TRP C CE3 1 ATOM 7577 C CZ2 . TRP C 1 122 ? -7.902 82.620 1.606 1.00 38.85 ? 155 TRP C CZ2 1 ATOM 7578 C CZ3 . TRP C 1 122 ? -10.190 83.180 1.031 1.00 38.07 ? 155 TRP C CZ3 1 ATOM 7579 C CH2 . TRP C 1 122 ? -8.811 83.465 1.009 1.00 38.77 ? 155 TRP C CH2 1 ATOM 7580 N N . PRO C 1 123 ? -11.188 82.299 5.040 1.00 21.52 ? 156 PRO C N 1 ATOM 7581 C CA . PRO C 1 123 ? -10.102 82.012 5.969 1.00 22.28 ? 156 PRO C CA 1 ATOM 7582 C C . PRO C 1 123 ? -10.508 81.588 7.347 1.00 22.94 ? 156 PRO C C 1 ATOM 7583 O O . PRO C 1 123 ? -11.477 82.087 7.900 1.00 25.13 ? 156 PRO C O 1 ATOM 7584 C CB . PRO C 1 123 ? -9.452 83.389 6.125 1.00 23.28 ? 156 PRO C CB 1 ATOM 7585 C CG . PRO C 1 123 ? -10.568 84.413 5.824 1.00 22.23 ? 156 PRO C CG 1 ATOM 7586 C CD . PRO C 1 123 ? -11.728 83.658 5.194 1.00 22.14 ? 156 PRO C CD 1 ATOM 7587 N N . GLN C 1 124 ? -9.732 80.736 7.971 1.00 25.28 ? 157 GLN C N 1 ATOM 7588 C CA . GLN C 1 124 ? -10.065 80.284 9.339 1.00 23.94 ? 157 GLN C CA 1 ATOM 7589 C C . GLN C 1 124 ? -10.608 81.353 10.252 1.00 22.64 ? 157 GLN C C 1 ATOM 7590 O O . GLN C 1 124 ? -10.118 82.493 10.239 1.00 22.59 ? 157 GLN C O 1 ATOM 7591 C CB . GLN C 1 124 ? -8.859 79.673 10.029 1.00 25.06 ? 157 GLN C CB 1 ATOM 7592 C CG . GLN C 1 124 ? -7.670 80.577 10.185 1.00 25.94 ? 157 GLN C CG 1 ATOM 7593 C CD . GLN C 1 124 ? -6.549 79.863 10.900 1.00 25.58 ? 157 GLN C CD 1 ATOM 7594 O OE1 . GLN C 1 124 ? -5.663 79.287 10.257 1.00 28.20 ? 157 GLN C OE1 1 ATOM 7595 N NE2 . GLN C 1 124 ? -6.616 79.842 12.223 1.00 23.16 ? 157 GLN C NE2 1 ATOM 7596 N N . ASP C 1 125 ? -11.636 80.968 11.021 1.00 22.07 ? 158 ASP C N 1 ATOM 7597 C CA . ASP C 1 125 ? -12.232 81.766 12.094 1.00 22.10 ? 158 ASP C CA 1 ATOM 7598 C C . ASP C 1 125 ? -13.175 82.928 11.650 1.00 22.83 ? 158 ASP C C 1 ATOM 7599 O O . ASP C 1 125 ? -13.818 83.594 12.489 1.00 21.80 ? 158 ASP C O 1 ATOM 7600 C CB . ASP C 1 125 ? -11.137 82.429 12.972 1.00 23.65 ? 158 ASP C CB 1 ATOM 7601 C CG . ASP C 1 125 ? -10.019 81.465 13.439 1.00 25.46 ? 158 ASP C CG 1 ATOM 7602 O OD1 . ASP C 1 125 ? -10.118 80.255 13.233 1.00 29.19 ? 158 ASP C OD1 1 ATOM 7603 O OD2 . ASP C 1 125 ? -9.003 81.936 14.013 1.00 27.32 -1 158 ASP C OD2 1 ATOM 7604 N N . GLN C 1 126 ? -13.208 83.266 10.368 1.00 21.46 ? 159 GLN C N 1 ATOM 7605 C CA . GLN C 1 126 ? -13.962 84.456 9.999 1.00 21.38 ? 159 GLN C CA 1 ATOM 7606 C C . GLN C 1 126 ? -15.365 83.942 9.507 1.00 22.01 ? 159 GLN C C 1 ATOM 7607 O O . GLN C 1 126 ? -15.836 84.367 8.413 1.00 21.34 ? 159 GLN C O 1 ATOM 7608 C CB . GLN C 1 126 ? -13.267 85.332 8.899 1.00 21.64 ? 159 GLN C CB 1 ATOM 7609 C CG . GLN C 1 126 ? -11.872 85.889 9.177 1.00 20.98 ? 159 GLN C CG 1 ATOM 7610 C CD . GLN C 1 126 ? -11.682 86.392 10.596 1.00 21.07 ? 159 GLN C CD 1 ATOM 7611 O OE1 . GLN C 1 126 ? -12.397 87.277 11.088 1.00 20.00 ? 159 GLN C OE1 1 ATOM 7612 N NE2 . GLN C 1 126 ? -10.719 85.816 11.270 1.00 20.80 ? 159 GLN C NE2 1 ATOM 7613 N N . LEU C 1 127 ? -16.018 83.038 10.269 1.00 20.02 ? 160 LEU C N 1 ATOM 7614 C CA . LEU C 1 127 ? -17.304 82.479 9.828 1.00 19.67 ? 160 LEU C CA 1 ATOM 7615 C C . LEU C 1 127 ? -18.444 83.494 9.939 1.00 19.85 ? 160 LEU C C 1 ATOM 7616 O O . LEU C 1 127 ? -18.600 84.237 10.936 1.00 15.79 ? 160 LEU C O 1 ATOM 7617 C CB . LEU C 1 127 ? -17.721 81.272 10.646 1.00 21.87 ? 160 LEU C CB 1 ATOM 7618 C CG . LEU C 1 127 ? -17.112 79.944 10.247 1.00 21.87 ? 160 LEU C CG 1 ATOM 7619 C CD1 . LEU C 1 127 ? -15.683 79.819 10.781 1.00 21.64 ? 160 LEU C CD1 1 ATOM 7620 C CD2 . LEU C 1 127 ? -18.004 78.906 10.850 1.00 22.22 ? 160 LEU C CD2 1 ATOM 7621 N N . PRO C 1 128 ? -19.282 83.489 8.925 1.00 20.83 ? 161 PRO C N 1 ATOM 7622 C CA . PRO C 1 128 ? -20.216 84.590 8.733 1.00 22.61 ? 161 PRO C CA 1 ATOM 7623 C C . PRO C 1 128 ? -21.620 84.337 9.324 1.00 23.27 ? 161 PRO C C 1 ATOM 7624 O O . PRO C 1 128 ? -21.990 83.167 9.602 1.00 19.76 ? 161 PRO C O 1 ATOM 7625 C CB . PRO C 1 128 ? -20.353 84.639 7.192 1.00 21.90 ? 161 PRO C CB 1 ATOM 7626 C CG . PRO C 1 128 ? -20.342 83.178 6.825 1.00 21.65 ? 161 PRO C CG 1 ATOM 7627 C CD . PRO C 1 128 ? -19.290 82.568 7.778 1.00 21.64 ? 161 PRO C CD 1 ATOM 7628 N N . VAL C 1 129 ? -22.358 85.463 9.398 1.00 23.33 ? 162 VAL C N 1 ATOM 7629 C CA . VAL C 1 129 ? -23.767 85.616 9.840 1.00 23.26 ? 162 VAL C CA 1 ATOM 7630 C C . VAL C 1 129 ? -24.851 85.226 8.813 1.00 20.97 ? 162 VAL C C 1 ATOM 7631 O O . VAL C 1 129 ? -25.934 84.813 9.150 1.00 19.85 ? 162 VAL C O 1 ATOM 7632 C CB . VAL C 1 129 ? -23.979 87.096 10.217 1.00 22.63 ? 162 VAL C CB 1 ATOM 7633 C CG1 . VAL C 1 129 ? -25.407 87.527 9.987 1.00 24.40 ? 162 VAL C CG1 1 ATOM 7634 C CG2 . VAL C 1 129 ? -23.586 87.300 11.654 1.00 21.74 ? 162 VAL C CG2 1 ATOM 7635 N N . VAL C 1 130 ? -24.546 85.373 7.551 1.00 21.15 ? 163 VAL C N 1 ATOM 7636 C CA . VAL C 1 130 ? -25.484 85.026 6.486 1.00 20.55 ? 163 VAL C CA 1 ATOM 7637 C C . VAL C 1 130 ? -24.944 83.784 5.760 1.00 18.74 ? 163 VAL C C 1 ATOM 7638 O O . VAL C 1 130 ? -23.860 83.314 6.108 1.00 19.82 ? 163 VAL C O 1 ATOM 7639 C CB . VAL C 1 130 ? -25.599 86.245 5.573 1.00 22.71 ? 163 VAL C CB 1 ATOM 7640 C CG1 . VAL C 1 130 ? -26.140 87.401 6.410 1.00 23.63 ? 163 VAL C CG1 1 ATOM 7641 C CG2 . VAL C 1 130 ? -24.229 86.631 4.924 1.00 22.22 ? 163 VAL C CG2 1 ATOM 7642 N N . THR C 1 131 ? -25.698 83.238 4.812 1.00 17.91 ? 164 THR C N 1 ATOM 7643 C CA . THR C 1 131 ? -25.272 82.109 3.909 1.00 18.49 ? 164 THR C CA 1 ATOM 7644 C C . THR C 1 131 ? -23.929 82.432 3.198 1.00 20.11 ? 164 THR C C 1 ATOM 7645 O O . THR C 1 131 ? -23.491 83.616 3.139 1.00 21.34 ? 164 THR C O 1 ATOM 7646 C CB . THR C 1 131 ? -26.434 81.671 2.902 1.00 17.83 ? 164 THR C CB 1 ATOM 7647 O OG1 . THR C 1 131 ? -26.173 80.424 2.262 1.00 16.71 ? 164 THR C OG1 1 ATOM 7648 C CG2 . THR C 1 131 ? -26.665 82.670 1.810 1.00 17.87 ? 164 THR C CG2 1 ATOM 7649 N N . SER C 1 132 ? -23.286 81.363 2.686 1.00 20.93 ? 165 SER C N 1 ATOM 7650 C CA . SER C 1 132 ? -21.914 81.381 2.145 1.00 18.82 ? 165 SER C CA 1 ATOM 7651 C C . SER C 1 132 ? -21.692 80.085 1.408 1.00 18.70 ? 165 SER C C 1 ATOM 7652 O O . SER C 1 132 ? -22.427 79.191 1.548 1.00 20.21 ? 165 SER C O 1 ATOM 7653 C CB . SER C 1 132 ? -20.949 81.497 3.276 1.00 18.47 ? 165 SER C CB 1 ATOM 7654 O OG . SER C 1 132 ? -20.970 80.291 4.028 1.00 21.07 ? 165 SER C OG 1 ATOM 7655 N N A LYS C 1 133 ? -20.663 79.998 0.584 0.50 20.41 ? 166 LYS C N 1 ATOM 7656 N N B LYS C 1 133 ? -20.674 79.990 0.583 0.50 21.51 ? 166 LYS C N 1 ATOM 7657 C CA A LYS C 1 133 ? -20.498 78.800 -0.267 0.50 21.00 ? 166 LYS C CA 1 ATOM 7658 C CA B LYS C 1 133 ? -20.553 78.802 -0.276 0.50 22.99 ? 166 LYS C CA 1 ATOM 7659 C C A LYS C 1 133 ? -20.416 77.618 0.670 0.50 21.25 ? 166 LYS C C 1 ATOM 7660 C C B LYS C 1 133 ? -20.389 77.603 0.649 0.50 22.40 ? 166 LYS C C 1 ATOM 7661 O O A LYS C 1 133 ? -21.058 76.608 0.445 0.50 21.70 ? 166 LYS C O 1 ATOM 7662 O O B LYS C 1 133 ? -20.939 76.549 0.384 0.50 22.83 ? 166 LYS C O 1 ATOM 7663 C CB A LYS C 1 133 ? -19.266 78.862 -1.245 0.50 19.65 ? 166 LYS C CB 1 ATOM 7664 C CB B LYS C 1 133 ? -19.399 78.923 -1.326 0.50 23.12 ? 166 LYS C CB 1 ATOM 7665 C CG A LYS C 1 133 ? -19.114 77.581 -2.117 0.50 18.66 ? 166 LYS C CG 1 ATOM 7666 C CG B LYS C 1 133 ? -19.691 78.268 -2.702 0.50 23.36 ? 166 LYS C CG 1 ATOM 7667 C CD A LYS C 1 133 ? -18.294 77.734 -3.390 0.50 17.06 ? 166 LYS C CD 1 ATOM 7668 C CD B LYS C 1 133 ? -20.020 76.778 -2.602 0.50 22.81 ? 166 LYS C CD 1 ATOM 7669 C CE A LYS C 1 133 ? -19.034 78.536 -4.448 0.50 15.94 ? 166 LYS C CE 1 ATOM 7670 C CE B LYS C 1 133 ? -21.086 76.321 -3.585 0.50 23.09 ? 166 LYS C CE 1 ATOM 7671 N NZ A LYS C 1 133 ? -19.718 77.656 -5.421 0.50 15.62 1 166 LYS C NZ 1 ATOM 7672 N NZ B LYS C 1 133 ? -21.923 75.180 -3.073 0.50 22.49 1 166 LYS C NZ 1 ATOM 7673 N N . VAL C 1 134 ? -19.676 77.802 1.760 1.00 23.04 ? 167 VAL C N 1 ATOM 7674 C CA . VAL C 1 134 ? -19.302 76.707 2.700 1.00 24.55 ? 167 VAL C CA 1 ATOM 7675 C C . VAL C 1 134 ? -20.485 76.105 3.410 1.00 21.32 ? 167 VAL C C 1 ATOM 7676 O O . VAL C 1 134 ? -20.628 74.887 3.453 1.00 19.44 ? 167 VAL C O 1 ATOM 7677 C CB . VAL C 1 134 ? -18.307 77.180 3.825 1.00 26.67 ? 167 VAL C CB 1 ATOM 7678 C CG1 . VAL C 1 134 ? -18.036 76.037 4.822 1.00 27.82 ? 167 VAL C CG1 1 ATOM 7679 C CG2 . VAL C 1 134 ? -17.010 77.723 3.262 1.00 25.75 ? 167 VAL C CG2 1 ATOM 7680 N N . TYR C 1 135 ? -21.282 77.013 3.974 1.00 21.62 ? 168 TYR C N 1 ATOM 7681 C CA . TYR C 1 135 ? -22.501 76.687 4.717 1.00 23.04 ? 168 TYR C CA 1 ATOM 7682 C C . TYR C 1 135 ? -23.432 75.939 3.820 1.00 22.66 ? 168 TYR C C 1 ATOM 7683 O O . TYR C 1 135 ? -24.080 75.019 4.273 1.00 22.02 ? 168 TYR C O 1 ATOM 7684 C CB . TYR C 1 135 ? -23.198 77.954 5.254 1.00 23.96 ? 168 TYR C CB 1 ATOM 7685 C CG . TYR C 1 135 ? -22.536 78.704 6.427 1.00 22.37 ? 168 TYR C CG 1 ATOM 7686 C CD1 . TYR C 1 135 ? -21.508 78.170 7.194 1.00 21.30 ? 168 TYR C CD1 1 ATOM 7687 C CD2 . TYR C 1 135 ? -23.040 79.926 6.796 1.00 23.89 ? 168 TYR C CD2 1 ATOM 7688 C CE1 . TYR C 1 135 ? -20.987 78.853 8.274 1.00 22.41 ? 168 TYR C CE1 1 ATOM 7689 C CE2 . TYR C 1 135 ? -22.529 80.641 7.871 1.00 24.37 ? 168 TYR C CE2 1 ATOM 7690 C CZ . TYR C 1 135 ? -21.498 80.099 8.618 1.00 23.71 ? 168 TYR C CZ 1 ATOM 7691 O OH . TYR C 1 135 ? -21.006 80.891 9.641 1.00 20.97 ? 168 TYR C OH 1 ATOM 7692 N N . ASN C 1 136 ? -23.453 76.316 2.529 1.00 21.50 ? 169 ASN C N 1 ATOM 7693 C CA . ASN C 1 136 ? -24.242 75.611 1.523 1.00 20.55 ? 169 ASN C CA 1 ATOM 7694 C C . ASN C 1 136 ? -23.688 74.254 1.071 1.00 21.95 ? 169 ASN C C 1 ATOM 7695 O O . ASN C 1 136 ? -24.476 73.284 0.868 1.00 24.78 ? 169 ASN C O 1 ATOM 7696 C CB . ASN C 1 136 ? -24.502 76.516 0.320 1.00 20.66 ? 169 ASN C CB 1 ATOM 7697 C CG . ASN C 1 136 ? -25.655 77.469 0.544 1.00 19.53 ? 169 ASN C CG 1 ATOM 7698 O OD1 . ASN C 1 136 ? -25.475 78.682 0.679 1.00 17.63 ? 169 ASN C OD1 1 ATOM 7699 N ND2 . ASN C 1 136 ? -26.848 76.930 0.554 1.00 19.32 ? 169 ASN C ND2 1 ATOM 7700 N N . ALA C 1 137 ? -22.363 74.159 0.909 1.00 20.74 ? 170 ALA C N 1 ATOM 7701 C CA . ALA C 1 137 ? -21.723 72.847 0.642 1.00 20.92 ? 170 ALA C CA 1 ATOM 7702 C C . ALA C 1 137 ? -21.842 71.837 1.818 1.00 19.84 ? 170 ALA C C 1 ATOM 7703 O O . ALA C 1 137 ? -22.061 70.635 1.607 1.00 17.98 ? 170 ALA C O 1 ATOM 7704 C CB . ALA C 1 137 ? -20.258 73.032 0.270 1.00 22.33 ? 170 ALA C CB 1 ATOM 7705 N N . VAL C 1 138 ? -21.710 72.330 3.048 1.00 20.03 ? 171 VAL C N 1 ATOM 7706 C CA . VAL C 1 138 ? -21.813 71.428 4.225 1.00 22.40 ? 171 VAL C CA 1 ATOM 7707 C C . VAL C 1 138 ? -23.284 70.923 4.253 1.00 25.16 ? 171 VAL C C 1 ATOM 7708 O O . VAL C 1 138 ? -23.549 69.738 4.443 1.00 24.66 ? 171 VAL C O 1 ATOM 7709 C CB . VAL C 1 138 ? -21.255 72.024 5.612 1.00 20.10 ? 171 VAL C CB 1 ATOM 7710 C CG1 . VAL C 1 138 ? -19.760 72.365 5.567 1.00 17.97 ? 171 VAL C CG1 1 ATOM 7711 C CG2 . VAL C 1 138 ? -22.080 73.220 6.126 1.00 19.27 ? 171 VAL C CG2 1 ATOM 7712 N N . ALA C 1 139 ? -24.221 71.828 3.962 1.00 30.63 ? 172 ALA C N 1 ATOM 7713 C CA . ALA C 1 139 ? -25.662 71.492 3.836 1.00 32.32 ? 172 ALA C CA 1 ATOM 7714 C C . ALA C 1 139 ? -25.932 70.375 2.765 1.00 32.05 ? 172 ALA C C 1 ATOM 7715 O O . ALA C 1 139 ? -26.658 69.375 3.036 1.00 26.22 ? 172 ALA C O 1 ATOM 7716 C CB . ALA C 1 139 ? -26.441 72.775 3.519 1.00 31.10 ? 172 ALA C CB 1 ATOM 7717 N N . ASN C 1 140 ? -25.335 70.562 1.571 1.00 31.33 ? 173 ASN C N 1 ATOM 7718 C CA . ASN C 1 140 ? -25.403 69.553 0.512 1.00 33.61 ? 173 ASN C CA 1 ATOM 7719 C C . ASN C 1 140 ? -24.732 68.265 0.934 1.00 32.54 ? 173 ASN C C 1 ATOM 7720 O O . ASN C 1 140 ? -25.234 67.178 0.662 1.00 34.52 ? 173 ASN C O 1 ATOM 7721 C CB . ASN C 1 140 ? -24.746 70.019 -0.810 1.00 38.20 ? 173 ASN C CB 1 ATOM 7722 C CG . ASN C 1 140 ? -25.417 71.240 -1.406 1.00 40.81 ? 173 ASN C CG 1 ATOM 7723 O OD1 . ASN C 1 140 ? -26.444 71.707 -0.907 1.00 43.78 ? 173 ASN C OD1 1 ATOM 7724 N ND2 . ASN C 1 140 ? -24.818 71.782 -2.458 1.00 37.98 ? 173 ASN C ND2 1 ATOM 7725 N N . LEU C 1 141 ? -23.579 68.401 1.565 1.00 29.81 ? 174 LEU C N 1 ATOM 7726 C CA . LEU C 1 141 ? -22.844 67.241 2.065 1.00 28.90 ? 174 LEU C CA 1 ATOM 7727 C C . LEU C 1 141 ? -23.492 66.455 3.204 1.00 26.59 ? 174 LEU C C 1 ATOM 7728 O O . LEU C 1 141 ? -23.323 65.240 3.245 1.00 27.56 ? 174 LEU C O 1 ATOM 7729 C CB . LEU C 1 141 ? -21.462 67.674 2.490 1.00 28.44 ? 174 LEU C CB 1 ATOM 7730 C CG . LEU C 1 141 ? -20.777 68.195 1.223 1.00 26.26 ? 174 LEU C CG 1 ATOM 7731 C CD1 . LEU C 1 141 ? -19.546 68.939 1.694 1.00 25.38 ? 174 LEU C CD1 1 ATOM 7732 C CD2 . LEU C 1 141 ? -20.458 67.035 0.291 1.00 26.30 ? 174 LEU C CD2 1 ATOM 7733 N N . TRP C 1 142 ? -24.263 67.124 4.064 1.00 24.51 ? 175 TRP C N 1 ATOM 7734 C CA . TRP C 1 142 ? -24.883 66.501 5.241 1.00 24.64 ? 175 TRP C CA 1 ATOM 7735 C C . TRP C 1 142 ? -26.423 66.206 5.157 1.00 28.52 ? 175 TRP C C 1 ATOM 7736 O O . TRP C 1 142 ? -26.993 65.690 6.135 1.00 29.06 ? 175 TRP C O 1 ATOM 7737 C CB . TRP C 1 142 ? -24.561 67.349 6.468 1.00 22.94 ? 175 TRP C CB 1 ATOM 7738 C CG . TRP C 1 142 ? -23.095 67.542 6.645 1.00 21.37 ? 175 TRP C CG 1 ATOM 7739 C CD1 . TRP C 1 142 ? -22.122 66.753 6.164 1.00 21.10 ? 175 TRP C CD1 1 ATOM 7740 C CD2 . TRP C 1 142 ? -22.443 68.634 7.288 1.00 19.92 ? 175 TRP C CD2 1 ATOM 7741 N NE1 . TRP C 1 142 ? -20.903 67.262 6.478 1.00 20.93 ? 175 TRP C NE1 1 ATOM 7742 C CE2 . TRP C 1 142 ? -21.070 68.415 7.187 1.00 19.84 ? 175 TRP C CE2 1 ATOM 7743 C CE3 . TRP C 1 142 ? -22.889 69.744 7.992 1.00 21.45 ? 175 TRP C CE3 1 ATOM 7744 C CZ2 . TRP C 1 142 ? -20.128 69.254 7.750 1.00 19.90 ? 175 TRP C CZ2 1 ATOM 7745 C CZ3 . TRP C 1 142 ? -21.929 70.583 8.603 1.00 21.95 ? 175 TRP C CZ3 1 ATOM 7746 C CH2 . TRP C 1 142 ? -20.575 70.339 8.457 1.00 20.49 ? 175 TRP C CH2 1 ATOM 7747 N N . LYS C 1 143 ? -27.066 66.523 4.015 1.00 31.14 ? 176 LYS C N 1 ATOM 7748 C CA . LYS C 1 143 ? -28.430 66.082 3.673 1.00 31.57 ? 176 LYS C CA 1 ATOM 7749 C C . LYS C 1 143 ? -28.819 64.634 4.096 1.00 32.26 ? 176 LYS C C 1 ATOM 7750 O O . LYS C 1 143 ? -29.933 64.431 4.616 1.00 34.99 ? 176 LYS C O 1 ATOM 7751 C CB . LYS C 1 143 ? -28.600 66.128 2.169 1.00 36.48 ? 176 LYS C CB 1 ATOM 7752 C CG . LYS C 1 143 ? -29.376 67.266 1.563 1.00 40.24 ? 176 LYS C CG 1 ATOM 7753 C CD . LYS C 1 143 ? -29.003 67.410 0.065 1.00 45.16 ? 176 LYS C CD 1 ATOM 7754 C CE . LYS C 1 143 ? -28.660 66.079 -0.682 1.00 47.92 ? 176 LYS C CE 1 ATOM 7755 N NZ . LYS C 1 143 ? -27.670 66.168 -1.824 1.00 46.15 1 176 LYS C NZ 1 ATOM 7756 N N . PRO C 1 144 ? -27.948 63.616 3.823 1.00 31.07 ? 177 PRO C N 1 ATOM 7757 C CA . PRO C 1 144 ? -28.228 62.189 4.243 1.00 30.28 ? 177 PRO C CA 1 ATOM 7758 C C . PRO C 1 144 ? -28.573 61.912 5.747 1.00 26.44 ? 177 PRO C C 1 ATOM 7759 O O . PRO C 1 144 ? -29.344 60.993 6.118 1.00 20.43 ? 177 PRO C O 1 ATOM 7760 C CB . PRO C 1 144 ? -26.918 61.459 3.831 1.00 31.99 ? 177 PRO C CB 1 ATOM 7761 C CG . PRO C 1 144 ? -26.375 62.253 2.636 1.00 30.08 ? 177 PRO C CG 1 ATOM 7762 C CD . PRO C 1 144 ? -26.764 63.691 2.913 1.00 31.07 ? 177 PRO C CD 1 ATOM 7763 N N . TRP C 1 145 ? -27.961 62.745 6.585 1.00 26.66 ? 178 TRP C N 1 ATOM 7764 C CA . TRP C 1 145 ? -28.076 62.707 8.048 1.00 24.20 ? 178 TRP C CA 1 ATOM 7765 C C . TRP C 1 145 ? -29.082 63.655 8.550 1.00 22.79 ? 178 TRP C C 1 ATOM 7766 O O . TRP C 1 145 ? -29.659 63.398 9.544 1.00 20.66 ? 178 TRP C O 1 ATOM 7767 C CB . TRP C 1 145 ? -26.771 63.123 8.683 1.00 23.89 ? 178 TRP C CB 1 ATOM 7768 C CG . TRP C 1 145 ? -25.672 62.195 8.410 1.00 25.21 ? 178 TRP C CG 1 ATOM 7769 C CD1 . TRP C 1 145 ? -25.753 60.845 8.271 1.00 26.91 ? 178 TRP C CD1 1 ATOM 7770 C CD2 . TRP C 1 145 ? -24.291 62.536 8.263 1.00 25.71 ? 178 TRP C CD2 1 ATOM 7771 N NE1 . TRP C 1 145 ? -24.503 60.325 8.025 1.00 28.39 ? 178 TRP C NE1 1 ATOM 7772 C CE2 . TRP C 1 145 ? -23.590 61.348 8.046 1.00 25.95 ? 178 TRP C CE2 1 ATOM 7773 C CE3 . TRP C 1 145 ? -23.592 63.734 8.296 1.00 28.49 ? 178 TRP C CE3 1 ATOM 7774 C CZ2 . TRP C 1 145 ? -22.238 61.315 7.902 1.00 27.01 ? 178 TRP C CZ2 1 ATOM 7775 C CZ3 . TRP C 1 145 ? -22.253 63.701 8.138 1.00 30.14 ? 178 TRP C CZ3 1 ATOM 7776 C CH2 . TRP C 1 145 ? -21.585 62.504 7.918 1.00 29.64 ? 178 TRP C CH2 1 ATOM 7777 N N . LEU C 1 146 ? -29.265 64.791 7.909 1.00 24.97 ? 179 LEU C N 1 ATOM 7778 C CA . LEU C 1 146 ? -30.091 65.834 8.529 1.00 28.22 ? 179 LEU C CA 1 ATOM 7779 C C . LEU C 1 146 ? -31.364 66.164 7.717 1.00 28.93 ? 179 LEU C C 1 ATOM 7780 O O . LEU C 1 146 ? -31.376 66.037 6.459 1.00 26.09 ? 179 LEU C O 1 ATOM 7781 C CB . LEU C 1 146 ? -29.223 67.086 8.790 1.00 28.63 ? 179 LEU C CB 1 ATOM 7782 C CG . LEU C 1 146 ? -27.979 66.876 9.705 1.00 28.79 ? 179 LEU C CG 1 ATOM 7783 C CD1 . LEU C 1 146 ? -27.207 68.189 9.672 1.00 30.44 ? 179 LEU C CD1 1 ATOM 7784 C CD2 . LEU C 1 146 ? -28.184 66.445 11.171 1.00 25.40 ? 179 LEU C CD2 1 ATOM 7785 N N . ASP C 1 147 ? -32.417 66.560 8.446 1.00 27.76 ? 180 ASP C N 1 ATOM 7786 C CA . ASP C 1 147 ? -33.698 66.931 7.831 1.00 29.13 ? 180 ASP C CA 1 ATOM 7787 C C . ASP C 1 147 ? -33.671 68.375 7.278 1.00 31.76 ? 180 ASP C C 1 ATOM 7788 O O . ASP C 1 147 ? -32.739 69.202 7.598 1.00 28.74 ? 180 ASP C O 1 ATOM 7789 C CB . ASP C 1 147 ? -34.858 66.775 8.814 1.00 30.25 ? 180 ASP C CB 1 ATOM 7790 C CG . ASP C 1 147 ? -35.089 65.330 9.235 1.00 31.74 ? 180 ASP C CG 1 ATOM 7791 O OD1 . ASP C 1 147 ? -34.402 64.444 8.676 1.00 32.66 ? 180 ASP C OD1 1 ATOM 7792 O OD2 . ASP C 1 147 ? -35.957 65.092 10.124 1.00 30.03 -1 180 ASP C OD2 1 ATOM 7793 N N . GLU C 1 148 ? -34.693 68.636 6.440 1.00 31.13 ? 181 GLU C N 1 ATOM 7794 C CA . GLU C 1 148 ? -34.856 69.860 5.656 1.00 31.03 ? 181 GLU C CA 1 ATOM 7795 C C . GLU C 1 148 ? -34.792 71.092 6.482 1.00 28.36 ? 181 GLU C C 1 ATOM 7796 O O . GLU C 1 148 ? -34.256 72.091 6.036 1.00 26.64 ? 181 GLU C O 1 ATOM 7797 C CB . GLU C 1 148 ? -36.229 69.915 5.012 1.00 38.05 ? 181 GLU C CB 1 ATOM 7798 C CG . GLU C 1 148 ? -36.453 68.980 3.847 1.00 47.34 ? 181 GLU C CG 1 ATOM 7799 C CD . GLU C 1 148 ? -37.921 68.957 3.393 1.00 55.53 ? 181 GLU C CD 1 ATOM 7800 O OE1 . GLU C 1 148 ? -38.159 69.199 2.170 1.00 48.26 ? 181 GLU C OE1 1 ATOM 7801 O OE2 . GLU C 1 148 ? -38.817 68.706 4.271 1.00 55.87 -1 181 GLU C OE2 1 ATOM 7802 N N . GLU C 1 149 ? -35.432 71.041 7.649 1.00 28.55 ? 182 GLU C N 1 ATOM 7803 C CA . GLU C 1 149 ? -35.507 72.183 8.544 1.00 29.02 ? 182 GLU C CA 1 ATOM 7804 C C . GLU C 1 149 ? -34.119 72.535 9.102 1.00 22.56 ? 182 GLU C C 1 ATOM 7805 O O . GLU C 1 149 ? -33.750 73.708 9.139 1.00 20.74 ? 182 GLU C O 1 ATOM 7806 C CB . GLU C 1 149 ? -36.553 71.967 9.647 1.00 34.81 ? 182 GLU C CB 1 ATOM 7807 C CG . GLU C 1 149 ? -38.013 71.886 9.150 1.00 42.17 ? 182 GLU C CG 1 ATOM 7808 C CD . GLU C 1 149 ? -38.521 70.455 8.769 1.00 47.25 ? 182 GLU C CD 1 ATOM 7809 O OE1 . GLU C 1 149 ? -37.724 69.472 8.693 1.00 45.33 ? 182 GLU C OE1 1 ATOM 7810 O OE2 . GLU C 1 149 ? -39.764 70.318 8.553 1.00 48.46 -1 182 GLU C OE2 1 ATOM 7811 N N . ALA C 1 150 ? -33.375 71.516 9.489 1.00 17.80 ? 183 ALA C N 1 ATOM 7812 C CA . ALA C 1 150 ? -31.973 71.606 9.835 1.00 17.21 ? 183 ALA C CA 1 ATOM 7813 C C . ALA C 1 150 ? -31.088 71.897 8.648 1.00 17.15 ? 183 ALA C C 1 ATOM 7814 O O . ALA C 1 150 ? -30.093 72.598 8.725 1.00 14.68 ? 183 ALA C O 1 ATOM 7815 C CB . ALA C 1 150 ? -31.520 70.270 10.414 1.00 19.13 ? 183 ALA C CB 1 ATOM 7816 N N . ILE C 1 151 ? -31.351 71.262 7.544 1.00 19.73 ? 184 ILE C N 1 ATOM 7817 C CA . ILE C 1 151 ? -30.523 71.613 6.397 1.00 24.70 ? 184 ILE C CA 1 ATOM 7818 C C . ILE C 1 151 ? -30.666 73.120 6.142 1.00 26.86 ? 184 ILE C C 1 ATOM 7819 O O . ILE C 1 151 ? -29.663 73.840 5.974 1.00 30.43 ? 184 ILE C O 1 ATOM 7820 C CB . ILE C 1 151 ? -30.826 70.682 5.188 1.00 25.78 ? 184 ILE C CB 1 ATOM 7821 C CG1 . ILE C 1 151 ? -29.838 69.494 5.252 1.00 26.40 ? 184 ILE C CG1 1 ATOM 7822 C CG2 . ILE C 1 151 ? -30.821 71.441 3.853 1.00 26.63 ? 184 ILE C CG2 1 ATOM 7823 C CD1 . ILE C 1 151 ? -28.458 69.756 5.914 1.00 25.30 ? 184 ILE C CD1 1 ATOM 7824 N N . SER C 1 152 ? -31.921 73.557 6.181 1.00 25.52 ? 185 SER C N 1 ATOM 7825 C CA . SER C 1 152 ? -32.335 74.938 6.071 1.00 27.99 ? 185 SER C CA 1 ATOM 7826 C C . SER C 1 152 ? -31.519 75.930 6.899 1.00 28.62 ? 185 SER C C 1 ATOM 7827 O O . SER C 1 152 ? -30.946 76.861 6.347 1.00 35.03 ? 185 SER C O 1 ATOM 7828 C CB . SER C 1 152 ? -33.820 75.053 6.517 1.00 28.39 ? 185 SER C CB 1 ATOM 7829 O OG . SER C 1 152 ? -34.498 75.981 5.753 1.00 27.81 ? 185 SER C OG 1 ATOM 7830 N N . THR C 1 153 ? -31.507 75.761 8.215 1.00 26.12 ? 186 THR C N 1 ATOM 7831 C CA . THR C 1 153 ? -30.834 76.690 9.079 1.00 26.58 ? 186 THR C CA 1 ATOM 7832 C C . THR C 1 153 ? -29.312 76.589 8.903 1.00 26.27 ? 186 THR C C 1 ATOM 7833 O O . THR C 1 153 ? -28.612 77.587 9.013 1.00 24.01 ? 186 THR C O 1 ATOM 7834 C CB . THR C 1 153 ? -31.202 76.414 10.507 1.00 27.75 ? 186 THR C CB 1 ATOM 7835 O OG1 . THR C 1 153 ? -32.630 76.431 10.608 1.00 30.86 ? 186 THR C OG1 1 ATOM 7836 C CG2 . THR C 1 153 ? -30.686 77.487 11.368 1.00 28.74 ? 186 THR C CG2 1 ATOM 7837 N N . LEU C 1 154 ? -28.816 75.402 8.555 1.00 25.23 ? 187 LEU C N 1 ATOM 7838 C CA . LEU C 1 154 ? -27.394 75.235 8.277 1.00 26.03 ? 187 LEU C CA 1 ATOM 7839 C C . LEU C 1 154 ? -26.896 76.181 7.166 1.00 25.35 ? 187 LEU C C 1 ATOM 7840 O O . LEU C 1 154 ? -25.969 76.955 7.393 1.00 21.28 ? 187 LEU C O 1 ATOM 7841 C CB . LEU C 1 154 ? -27.034 73.767 7.970 1.00 25.86 ? 187 LEU C CB 1 ATOM 7842 C CG . LEU C 1 154 ? -25.590 73.337 8.327 1.00 26.31 ? 187 LEU C CG 1 ATOM 7843 C CD1 . LEU C 1 154 ? -25.074 73.861 9.677 1.00 24.12 ? 187 LEU C CD1 1 ATOM 7844 C CD2 . LEU C 1 154 ? -25.463 71.804 8.293 1.00 27.99 ? 187 LEU C CD2 1 ATOM 7845 N N . ARG C 1 155 ? -27.527 76.133 5.998 1.00 23.53 ? 188 ARG C N 1 ATOM 7846 C CA . ARG C 1 155 ? -27.231 77.120 4.990 1.00 26.42 ? 188 ARG C CA 1 ATOM 7847 C C . ARG C 1 155 ? -27.109 78.584 5.482 1.00 27.57 ? 188 ARG C C 1 ATOM 7848 O O . ARG C 1 155 ? -26.348 79.386 4.902 1.00 26.13 ? 188 ARG C O 1 ATOM 7849 C CB . ARG C 1 155 ? -28.321 77.142 3.943 1.00 28.84 ? 188 ARG C CB 1 ATOM 7850 C CG . ARG C 1 155 ? -28.451 75.865 3.171 1.00 28.85 ? 188 ARG C CG 1 ATOM 7851 C CD . ARG C 1 155 ? -29.470 76.082 2.099 1.00 27.84 ? 188 ARG C CD 1 ATOM 7852 N NE . ARG C 1 155 ? -29.707 74.857 1.367 1.00 29.96 ? 188 ARG C NE 1 ATOM 7853 C CZ . ARG C 1 155 ? -28.784 74.093 0.774 1.00 31.14 ? 188 ARG C CZ 1 ATOM 7854 N NH1 . ARG C 1 155 ? -27.469 74.345 0.824 1.00 30.25 1 188 ARG C NH1 1 ATOM 7855 N NH2 . ARG C 1 155 ? -29.199 73.027 0.104 1.00 31.83 ? 188 ARG C NH2 1 ATOM 7856 N N . LYS C 1 156 ? -27.859 78.939 6.508 1.00 25.68 ? 189 LYS C N 1 ATOM 7857 C CA . LYS C 1 156 ? -27.993 80.321 6.809 1.00 28.30 ? 189 LYS C CA 1 ATOM 7858 C C . LYS C 1 156 ? -27.113 80.835 7.896 1.00 28.38 ? 189 LYS C C 1 ATOM 7859 O O . LYS C 1 156 ? -26.873 82.039 7.978 1.00 31.66 ? 189 LYS C O 1 ATOM 7860 C CB . LYS C 1 156 ? -29.431 80.591 7.211 1.00 33.36 ? 189 LYS C CB 1 ATOM 7861 C CG . LYS C 1 156 ? -30.346 80.814 6.022 1.00 41.30 ? 189 LYS C CG 1 ATOM 7862 C CD . LYS C 1 156 ? -31.762 80.323 6.299 1.00 48.96 ? 189 LYS C CD 1 ATOM 7863 C CE . LYS C 1 156 ? -32.799 81.028 5.424 1.00 53.71 ? 189 LYS C CE 1 ATOM 7864 N NZ . LYS C 1 156 ? -32.491 80.833 3.975 1.00 56.19 1 189 LYS C NZ 1 ATOM 7865 N N . GLY C 1 157 ? -26.759 79.947 8.831 1.00 28.31 ? 190 GLY C N 1 ATOM 7866 C CA . GLY C 1 157 ? -26.047 80.322 10.061 1.00 20.60 ? 190 GLY C CA 1 ATOM 7867 C C . GLY C 1 157 ? -24.946 79.367 10.371 1.00 16.66 ? 190 GLY C C 1 ATOM 7868 O O . GLY C 1 157 ? -24.121 79.719 11.160 1.00 14.79 ? 190 GLY C O 1 ATOM 7869 N N . GLY C 1 158 ? -24.891 78.205 9.725 1.00 15.11 ? 191 GLY C N 1 ATOM 7870 C CA . GLY C 1 158 ? -23.952 77.140 10.132 1.00 16.95 ? 191 GLY C CA 1 ATOM 7871 C C . GLY C 1 158 ? -24.365 76.402 11.440 1.00 18.46 ? 191 GLY C C 1 ATOM 7872 O O . GLY C 1 158 ? -23.540 75.832 12.137 1.00 17.55 ? 191 GLY C O 1 ATOM 7873 N N . PHE C 1 159 ? -25.656 76.436 11.772 1.00 19.67 ? 192 PHE C N 1 ATOM 7874 C CA . PHE C 1 159 ? -26.176 75.767 12.932 1.00 20.71 ? 192 PHE C CA 1 ATOM 7875 C C . PHE C 1 159 ? -27.542 75.079 12.608 1.00 21.13 ? 192 PHE C C 1 ATOM 7876 O O . PHE C 1 159 ? -28.174 75.373 11.579 1.00 24.68 ? 192 PHE C O 1 ATOM 7877 C CB . PHE C 1 159 ? -26.236 76.771 14.072 1.00 21.68 ? 192 PHE C CB 1 ATOM 7878 C CG . PHE C 1 159 ? -27.276 77.890 13.900 1.00 23.95 ? 192 PHE C CG 1 ATOM 7879 C CD1 . PHE C 1 159 ? -28.635 77.696 14.253 1.00 23.92 ? 192 PHE C CD1 1 ATOM 7880 C CD2 . PHE C 1 159 ? -26.881 79.181 13.521 1.00 24.76 ? 192 PHE C CD2 1 ATOM 7881 C CE1 . PHE C 1 159 ? -29.556 78.725 14.145 1.00 24.53 ? 192 PHE C CE1 1 ATOM 7882 C CE2 . PHE C 1 159 ? -27.823 80.239 13.421 1.00 25.22 ? 192 PHE C CE2 1 ATOM 7883 C CZ . PHE C 1 159 ? -29.159 79.993 13.704 1.00 25.93 ? 192 PHE C CZ 1 ATOM 7884 N N . TYR C 1 160 ? -27.963 74.106 13.414 1.00 18.88 ? 193 TYR C N 1 ATOM 7885 C CA . TYR C 1 160 ? -29.232 73.415 13.192 1.00 17.84 ? 193 TYR C CA 1 ATOM 7886 C C . TYR C 1 160 ? -29.644 72.648 14.420 1.00 19.46 ? 193 TYR C C 1 ATOM 7887 O O . TYR C 1 160 ? -28.835 72.457 15.352 1.00 22.47 ? 193 TYR C O 1 ATOM 7888 C CB . TYR C 1 160 ? -29.140 72.456 12.023 1.00 16.49 ? 193 TYR C CB 1 ATOM 7889 C CG . TYR C 1 160 ? -28.216 71.357 12.277 1.00 15.56 ? 193 TYR C CG 1 ATOM 7890 C CD1 . TYR C 1 160 ? -26.873 71.495 12.017 1.00 14.56 ? 193 TYR C CD1 1 ATOM 7891 C CD2 . TYR C 1 160 ? -28.684 70.168 12.787 1.00 15.75 ? 193 TYR C CD2 1 ATOM 7892 C CE1 . TYR C 1 160 ? -25.999 70.477 12.274 1.00 14.58 ? 193 TYR C CE1 1 ATOM 7893 C CE2 . TYR C 1 160 ? -27.828 69.131 13.087 1.00 16.29 ? 193 TYR C CE2 1 ATOM 7894 C CZ . TYR C 1 160 ? -26.457 69.276 12.821 1.00 15.78 ? 193 TYR C CZ 1 ATOM 7895 O OH . TYR C 1 160 ? -25.590 68.208 13.114 1.00 14.32 ? 193 TYR C OH 1 ATOM 7896 N N . SER C 1 161 ? -30.885 72.193 14.468 1.00 19.65 ? 194 SER C N 1 ATOM 7897 C CA . SER C 1 161 ? -31.158 71.073 15.402 1.00 21.75 ? 194 SER C CA 1 ATOM 7898 C C . SER C 1 161 ? -31.818 69.938 14.653 1.00 20.04 ? 194 SER C C 1 ATOM 7899 O O . SER C 1 161 ? -32.345 70.137 13.565 1.00 20.16 ? 194 SER C O 1 ATOM 7900 C CB . SER C 1 161 ? -32.012 71.463 16.613 1.00 22.26 ? 194 SER C CB 1 ATOM 7901 O OG . SER C 1 161 ? -33.377 71.452 16.250 1.00 21.77 ? 194 SER C OG 1 ATOM 7902 N N . GLN C 1 162 ? -31.794 68.754 15.252 1.00 19.63 ? 195 GLN C N 1 ATOM 7903 C CA . GLN C 1 162 ? -32.161 67.557 14.556 1.00 19.69 ? 195 GLN C CA 1 ATOM 7904 C C . GLN C 1 162 ? -32.561 66.459 15.571 1.00 22.11 ? 195 GLN C C 1 ATOM 7905 O O . GLN C 1 162 ? -31.946 66.340 16.606 1.00 24.76 ? 195 GLN C O 1 ATOM 7906 C CB . GLN C 1 162 ? -30.983 67.226 13.703 1.00 18.80 ? 195 GLN C CB 1 ATOM 7907 C CG . GLN C 1 162 ? -31.126 65.981 12.932 1.00 20.72 ? 195 GLN C CG 1 ATOM 7908 C CD . GLN C 1 162 ? -32.377 65.892 12.108 1.00 21.17 ? 195 GLN C CD 1 ATOM 7909 O OE1 . GLN C 1 162 ? -32.472 66.542 11.052 1.00 21.37 ? 195 GLN C OE1 1 ATOM 7910 N NE2 . GLN C 1 162 ? -33.297 64.982 12.512 1.00 20.26 ? 195 GLN C NE2 1 ATOM 7911 N N . LYS C 1 163 ? -33.659 65.752 15.322 1.00 23.26 ? 196 LYS C N 1 ATOM 7912 C CA . LYS C 1 163 ? -34.085 64.616 16.148 1.00 24.43 ? 196 LYS C CA 1 ATOM 7913 C C . LYS C 1 163 ? -33.345 63.390 15.666 1.00 24.39 ? 196 LYS C C 1 ATOM 7914 O O . LYS C 1 163 ? -32.978 63.319 14.514 1.00 23.50 ? 196 LYS C O 1 ATOM 7915 C CB . LYS C 1 163 ? -35.610 64.403 16.155 1.00 25.52 ? 196 LYS C CB 1 ATOM 7916 C CG . LYS C 1 163 ? -36.293 65.480 17.028 1.00 30.50 ? 196 LYS C CG 1 ATOM 7917 C CD . LYS C 1 163 ? -37.706 65.906 16.611 1.00 31.91 ? 196 LYS C CD 1 ATOM 7918 C CE . LYS C 1 163 ? -37.701 66.829 15.405 1.00 33.93 ? 196 LYS C CE 1 ATOM 7919 N NZ . LYS C 1 163 ? -38.962 66.779 14.609 1.00 34.29 1 196 LYS C NZ 1 ATOM 7920 N N . VAL C 1 164 ? -33.084 62.492 16.612 1.00 23.99 ? 197 VAL C N 1 ATOM 7921 C CA . VAL C 1 164 ? -32.315 61.269 16.459 1.00 26.12 ? 197 VAL C CA 1 ATOM 7922 C C . VAL C 1 164 ? -33.251 60.154 15.989 1.00 25.36 ? 197 VAL C C 1 ATOM 7923 O O . VAL C 1 164 ? -34.242 59.820 16.725 1.00 23.66 ? 197 VAL C O 1 ATOM 7924 C CB . VAL C 1 164 ? -31.731 60.799 17.876 1.00 27.84 ? 197 VAL C CB 1 ATOM 7925 C CG1 . VAL C 1 164 ? -30.985 59.462 17.794 1.00 25.53 ? 197 VAL C CG1 1 ATOM 7926 C CG2 . VAL C 1 164 ? -30.839 61.854 18.519 1.00 27.73 ? 197 VAL C CG2 1 ATOM 7927 N N . THR C 1 165 ? -32.926 59.541 14.833 1.00 25.93 ? 198 THR C N 1 ATOM 7928 C CA . THR C 1 165 ? -33.812 58.528 14.216 1.00 27.77 ? 198 THR C CA 1 ATOM 7929 C C . THR C 1 165 ? -34.086 57.428 15.193 1.00 26.37 ? 198 THR C C 1 ATOM 7930 O O . THR C 1 165 ? -35.230 57.171 15.468 1.00 29.85 ? 198 THR C O 1 ATOM 7931 C CB . THR C 1 165 ? -33.317 57.985 12.881 1.00 29.77 ? 198 THR C CB 1 ATOM 7932 O OG1 . THR C 1 165 ? -33.278 59.069 11.957 1.00 33.41 ? 198 THR C OG1 1 ATOM 7933 C CG2 . THR C 1 165 ? -34.270 56.928 12.304 1.00 29.32 ? 198 THR C CG2 1 ATOM 7934 N N . THR C 1 166 ? -33.066 56.865 15.794 1.00 25.71 ? 199 THR C N 1 ATOM 7935 C CA . THR C 1 166 ? -33.225 55.845 16.878 1.00 29.44 ? 199 THR C CA 1 ATOM 7936 C C . THR C 1 166 ? -33.796 56.280 18.323 1.00 31.21 ? 199 THR C C 1 ATOM 7937 O O . THR C 1 166 ? -34.033 55.448 19.216 1.00 24.47 ? 199 THR C O 1 ATOM 7938 C CB . THR C 1 166 ? -31.847 55.191 17.121 1.00 30.71 ? 199 THR C CB 1 ATOM 7939 O OG1 . THR C 1 166 ? -30.905 56.211 17.532 1.00 36.94 ? 199 THR C OG1 1 ATOM 7940 C CG2 . THR C 1 166 ? -31.313 54.469 15.837 1.00 29.74 ? 199 THR C CG2 1 ATOM 7941 N N . ASN C 1 167 ? -33.947 57.580 18.559 1.00 31.52 ? 200 ASN C N 1 ATOM 7942 C CA . ASN C 1 167 ? -34.395 58.076 19.850 1.00 32.04 ? 200 ASN C CA 1 ATOM 7943 C C . ASN C 1 167 ? -35.051 59.442 19.571 1.00 33.36 ? 200 ASN C C 1 ATOM 7944 O O . ASN C 1 167 ? -34.435 60.483 19.805 1.00 31.12 ? 200 ASN C O 1 ATOM 7945 C CB . ASN C 1 167 ? -33.209 58.174 20.819 1.00 31.96 ? 200 ASN C CB 1 ATOM 7946 C CG . ASN C 1 167 ? -32.711 56.799 21.288 1.00 31.89 ? 200 ASN C CG 1 ATOM 7947 O OD1 . ASN C 1 167 ? -33.359 56.157 22.147 1.00 39.58 ? 200 ASN C OD1 1 ATOM 7948 N ND2 . ASN C 1 167 ? -31.584 56.343 20.751 1.00 24.48 ? 200 ASN C ND2 1 ATOM 7949 N N . PRO C 1 168 ? -36.301 59.433 19.023 1.00 33.41 ? 201 PRO C N 1 ATOM 7950 C CA . PRO C 1 168 ? -36.816 60.711 18.415 1.00 32.13 ? 201 PRO C CA 1 ATOM 7951 C C . PRO C 1 168 ? -37.225 61.829 19.414 1.00 29.68 ? 201 PRO C C 1 ATOM 7952 O O . PRO C 1 168 ? -37.264 62.984 19.007 1.00 29.66 ? 201 PRO C O 1 ATOM 7953 C CB . PRO C 1 168 ? -37.975 60.268 17.494 1.00 29.10 ? 201 PRO C CB 1 ATOM 7954 C CG . PRO C 1 168 ? -37.900 58.762 17.538 1.00 34.06 ? 201 PRO C CG 1 ATOM 7955 C CD . PRO C 1 168 ? -37.223 58.305 18.796 1.00 29.48 ? 201 PRO C CD 1 ATOM 7956 N N . ASN C 1 169 ? -37.508 61.498 20.680 1.00 26.50 ? 202 ASN C N 1 ATOM 7957 C CA . ASN C 1 169 ? -37.577 62.515 21.752 1.00 27.64 ? 202 ASN C CA 1 ATOM 7958 C C . ASN C 1 169 ? -36.177 63.018 22.293 1.00 26.22 ? 202 ASN C C 1 ATOM 7959 O O . ASN C 1 169 ? -36.119 63.744 23.281 1.00 26.91 ? 202 ASN C O 1 ATOM 7960 C CB . ASN C 1 169 ? -38.432 62.006 22.915 1.00 28.15 ? 202 ASN C CB 1 ATOM 7961 C CG . ASN C 1 169 ? -37.883 60.706 23.506 1.00 30.64 ? 202 ASN C CG 1 ATOM 7962 O OD1 . ASN C 1 169 ? -37.022 60.026 22.896 1.00 29.73 ? 202 ASN C OD1 1 ATOM 7963 N ND2 . ASN C 1 169 ? -38.389 60.338 24.689 1.00 31.82 ? 202 ASN C ND2 1 ATOM 7964 N N . LEU C 1 170 ? -35.075 62.615 21.668 1.00 23.39 ? 203 LEU C N 1 ATOM 7965 C CA . LEU C 1 170 ? -33.764 63.201 21.924 1.00 23.26 ? 203 LEU C CA 1 ATOM 7966 C C . LEU C 1 170 ? -33.418 64.143 20.722 1.00 20.96 ? 203 LEU C C 1 ATOM 7967 O O . LEU C 1 170 ? -33.394 63.742 19.596 1.00 20.50 ? 203 LEU C O 1 ATOM 7968 C CB . LEU C 1 170 ? -32.726 62.050 22.193 1.00 23.57 ? 203 LEU C CB 1 ATOM 7969 C CG . LEU C 1 170 ? -31.204 62.439 22.259 1.00 24.99 ? 203 LEU C CG 1 ATOM 7970 C CD1 . LEU C 1 170 ? -31.042 63.451 23.427 1.00 24.81 ? 203 LEU C CD1 1 ATOM 7971 C CD2 . LEU C 1 170 ? -30.153 61.293 22.341 1.00 21.44 ? 203 LEU C CD2 1 ATOM 7972 N N . ARG C 1 171 ? -33.189 65.408 20.945 1.00 22.97 ? 204 ARG C N 1 ATOM 7973 C CA . ARG C 1 171 ? -32.775 66.316 19.835 1.00 24.27 ? 204 ARG C CA 1 ATOM 7974 C C . ARG C 1 171 ? -31.365 66.891 20.089 1.00 23.58 ? 204 ARG C C 1 ATOM 7975 O O . ARG C 1 171 ? -31.051 67.379 21.231 1.00 24.39 ? 204 ARG C O 1 ATOM 7976 C CB . ARG C 1 171 ? -33.760 67.465 19.705 1.00 26.70 ? 204 ARG C CB 1 ATOM 7977 C CG . ARG C 1 171 ? -33.265 68.717 18.983 1.00 28.35 ? 204 ARG C CG 1 ATOM 7978 C CD . ARG C 1 171 ? -34.194 69.929 19.292 1.00 29.98 ? 204 ARG C CD 1 ATOM 7979 N NE . ARG C 1 171 ? -35.630 69.679 19.049 1.00 29.06 ? 204 ARG C NE 1 ATOM 7980 C CZ . ARG C 1 171 ? -36.251 69.719 17.860 1.00 31.75 ? 204 ARG C CZ 1 ATOM 7981 N NH1 . ARG C 1 171 ? -35.630 70.029 16.715 1.00 28.37 1 204 ARG C NH1 1 ATOM 7982 N NH2 . ARG C 1 171 ? -37.552 69.466 17.825 1.00 36.56 ? 204 ARG C NH2 1 ATOM 7983 N N . ILE C 1 172 ? -30.539 66.854 19.028 1.00 19.56 ? 205 ILE C N 1 ATOM 7984 C CA . ILE C 1 172 ? -29.185 67.339 19.033 1.00 15.88 ? 205 ILE C CA 1 ATOM 7985 C C . ILE C 1 172 ? -29.387 68.704 18.555 1.00 16.19 ? 205 ILE C C 1 ATOM 7986 O O . ILE C 1 172 ? -30.043 68.877 17.546 1.00 16.09 ? 205 ILE C O 1 ATOM 7987 C CB . ILE C 1 172 ? -28.306 66.619 17.993 1.00 16.17 ? 205 ILE C CB 1 ATOM 7988 C CG1 . ILE C 1 172 ? -28.125 65.096 18.296 1.00 16.26 ? 205 ILE C CG1 1 ATOM 7989 C CG2 . ILE C 1 172 ? -26.941 67.265 17.863 1.00 16.33 ? 205 ILE C CG2 1 ATOM 7990 C CD1 . ILE C 1 172 ? -27.781 64.691 19.708 1.00 15.16 ? 205 ILE C CD1 1 ATOM 7991 N N . ILE C 1 173 ? -28.863 69.670 19.324 1.00 17.51 ? 206 ILE C N 1 ATOM 7992 C CA . ILE C 1 173 ? -28.674 71.097 18.953 1.00 17.77 ? 206 ILE C CA 1 ATOM 7993 C C . ILE C 1 173 ? -27.177 71.409 18.595 1.00 16.72 ? 206 ILE C C 1 ATOM 7994 O O . ILE C 1 173 ? -26.323 71.354 19.486 1.00 17.76 ? 206 ILE C O 1 ATOM 7995 C CB . ILE C 1 173 ? -29.098 72.025 20.156 1.00 19.21 ? 206 ILE C CB 1 ATOM 7996 C CG1 . ILE C 1 173 ? -30.557 71.819 20.527 1.00 19.63 ? 206 ILE C CG1 1 ATOM 7997 C CG2 . ILE C 1 173 ? -28.907 73.524 19.834 1.00 19.02 ? 206 ILE C CG2 1 ATOM 7998 C CD1 . ILE C 1 173 ? -31.103 72.862 21.494 1.00 20.51 ? 206 ILE C CD1 1 ATOM 7999 N N . SER C 1 174 ? -26.876 71.777 17.346 1.00 14.46 ? 207 SER C N 1 ATOM 8000 C CA . SER C 1 174 ? -25.509 71.839 16.879 1.00 13.73 ? 207 SER C CA 1 ATOM 8001 C C . SER C 1 174 ? -25.218 73.273 16.621 1.00 14.58 ? 207 SER C C 1 ATOM 8002 O O . SER C 1 174 ? -25.714 73.857 15.697 1.00 15.55 ? 207 SER C O 1 ATOM 8003 C CB . SER C 1 174 ? -25.325 70.980 15.621 1.00 13.50 ? 207 SER C CB 1 ATOM 8004 O OG . SER C 1 174 ? -24.029 71.006 15.085 1.00 11.67 ? 207 SER C OG 1 ATOM 8005 N N . LEU C 1 175 ? -24.459 73.880 17.510 1.00 15.99 ? 208 LEU C N 1 ATOM 8006 C CA . LEU C 1 175 ? -24.249 75.307 17.483 1.00 16.39 ? 208 LEU C CA 1 ATOM 8007 C C . LEU C 1 175 ? -22.939 75.633 16.744 1.00 17.90 ? 208 LEU C C 1 ATOM 8008 O O . LEU C 1 175 ? -21.949 74.906 16.909 1.00 20.79 ? 208 LEU C O 1 ATOM 8009 C CB . LEU C 1 175 ? -24.159 75.901 18.905 1.00 15.22 ? 208 LEU C CB 1 ATOM 8010 C CG . LEU C 1 175 ? -25.309 75.837 19.883 1.00 13.94 ? 208 LEU C CG 1 ATOM 8011 C CD1 . LEU C 1 175 ? -24.855 76.523 21.162 1.00 12.69 ? 208 LEU C CD1 1 ATOM 8012 C CD2 . LEU C 1 175 ? -26.551 76.441 19.310 1.00 13.03 ? 208 LEU C CD2 1 ATOM 8013 N N . ASN C 1 176 ? -22.960 76.750 15.986 1.00 18.29 ? 209 ASN C N 1 ATOM 8014 C CA . ASN C 1 176 ? -21.757 77.527 15.526 1.00 17.88 ? 209 ASN C CA 1 ATOM 8015 C C . ASN C 1 176 ? -21.310 78.494 16.611 1.00 15.99 ? 209 ASN C C 1 ATOM 8016 O O . ASN C 1 176 ? -21.721 79.656 16.637 1.00 14.55 ? 209 ASN C O 1 ATOM 8017 C CB . ASN C 1 176 ? -22.043 78.308 14.212 1.00 18.73 ? 209 ASN C CB 1 ATOM 8018 C CG . ASN C 1 176 ? -20.793 78.562 13.350 1.00 20.44 ? 209 ASN C CG 1 ATOM 8019 O OD1 . ASN C 1 176 ? -19.651 78.362 13.778 1.00 19.32 ? 209 ASN C OD1 1 ATOM 8020 N ND2 . ASN C 1 176 ? -21.034 78.973 12.066 1.00 22.01 ? 209 ASN C ND2 1 ATOM 8021 N N . THR C 1 177 ? -20.492 77.980 17.523 1.00 15.22 ? 210 THR C N 1 ATOM 8022 C CA . THR C 1 177 ? -19.867 78.827 18.508 1.00 15.65 ? 210 THR C CA 1 ATOM 8023 C C . THR C 1 177 ? -18.798 79.655 17.753 1.00 16.61 ? 210 THR C C 1 ATOM 8024 O O . THR C 1 177 ? -18.342 80.668 18.237 1.00 17.07 ? 210 THR C O 1 ATOM 8025 C CB . THR C 1 177 ? -19.291 78.047 19.749 1.00 14.96 ? 210 THR C CB 1 ATOM 8026 O OG1 . THR C 1 177 ? -18.485 76.912 19.365 1.00 15.67 ? 210 THR C OG1 1 ATOM 8027 C CG2 . THR C 1 177 ? -20.361 77.558 20.537 1.00 14.33 ? 210 THR C CG2 1 ATOM 8028 N N . ASN C 1 178 ? -18.417 79.245 16.549 1.00 16.99 ? 211 ASN C N 1 ATOM 8029 C CA . ASN C 1 178 ? -17.227 79.830 15.962 1.00 17.96 ? 211 ASN C CA 1 ATOM 8030 C C . ASN C 1 178 ? -17.557 81.319 15.859 1.00 18.34 ? 211 ASN C C 1 ATOM 8031 O O . ASN C 1 178 ? -16.697 82.196 15.985 1.00 17.04 ? 211 ASN C O 1 ATOM 8032 C CB . ASN C 1 178 ? -16.830 79.122 14.640 1.00 17.78 ? 211 ASN C CB 1 ATOM 8033 C CG . ASN C 1 178 ? -16.523 77.628 14.828 1.00 16.81 ? 211 ASN C CG 1 ATOM 8034 O OD1 . ASN C 1 178 ? -17.296 76.745 14.506 1.00 15.29 ? 211 ASN C OD1 1 ATOM 8035 N ND2 . ASN C 1 178 ? -15.419 77.371 15.428 1.00 18.40 ? 211 ASN C ND2 1 ATOM 8036 N N . LEU C 1 179 ? -18.855 81.573 15.792 1.00 19.06 ? 212 LEU C N 1 ATOM 8037 C CA . LEU C 1 179 ? -19.380 82.912 15.652 1.00 20.37 ? 212 LEU C CA 1 ATOM 8038 C C . LEU C 1 179 ? -19.040 83.822 16.850 1.00 21.39 ? 212 LEU C C 1 ATOM 8039 O O . LEU C 1 179 ? -18.997 85.044 16.697 1.00 23.07 ? 212 LEU C O 1 ATOM 8040 C CB . LEU C 1 179 ? -20.918 82.849 15.390 1.00 19.95 ? 212 LEU C CB 1 ATOM 8041 C CG . LEU C 1 179 ? -21.368 82.365 14.014 1.00 20.15 ? 212 LEU C CG 1 ATOM 8042 C CD1 . LEU C 1 179 ? -22.893 82.228 13.911 1.00 21.52 ? 212 LEU C CD1 1 ATOM 8043 C CD2 . LEU C 1 179 ? -20.869 83.357 12.998 1.00 19.73 ? 212 LEU C CD2 1 ATOM 8044 N N . TYR C 1 180 ? -18.856 83.217 18.026 1.00 21.34 ? 213 TYR C N 1 ATOM 8045 C CA . TYR C 1 180 ? -18.491 83.911 19.287 1.00 20.13 ? 213 TYR C CA 1 ATOM 8046 C C . TYR C 1 180 ? -17.002 83.822 19.623 1.00 19.43 ? 213 TYR C C 1 ATOM 8047 O O . TYR C 1 180 ? -16.585 84.288 20.650 1.00 20.99 ? 213 TYR C O 1 ATOM 8048 C CB . TYR C 1 180 ? -19.213 83.296 20.449 1.00 19.74 ? 213 TYR C CB 1 ATOM 8049 C CG . TYR C 1 180 ? -20.666 83.140 20.228 1.00 20.56 ? 213 TYR C CG 1 ATOM 8050 C CD1 . TYR C 1 180 ? -21.417 84.115 19.565 1.00 19.51 ? 213 TYR C CD1 1 ATOM 8051 C CD2 . TYR C 1 180 ? -21.305 81.969 20.621 1.00 20.96 ? 213 TYR C CD2 1 ATOM 8052 C CE1 . TYR C 1 180 ? -22.798 83.946 19.366 1.00 19.06 ? 213 TYR C CE1 1 ATOM 8053 C CE2 . TYR C 1 180 ? -22.685 81.761 20.375 1.00 21.95 ? 213 TYR C CE2 1 ATOM 8054 C CZ . TYR C 1 180 ? -23.441 82.753 19.770 1.00 19.26 ? 213 TYR C CZ 1 ATOM 8055 O OH . TYR C 1 180 ? -24.788 82.521 19.637 1.00 16.23 ? 213 TYR C OH 1 ATOM 8056 N N . TYR C 1 181 ? -16.214 83.232 18.732 1.00 19.02 ? 214 TYR C N 1 ATOM 8057 C CA . TYR C 1 181 ? -14.800 83.051 18.882 1.00 17.92 ? 214 TYR C CA 1 ATOM 8058 C C . TYR C 1 181 ? -14.030 84.379 18.737 1.00 19.07 ? 214 TYR C C 1 ATOM 8059 O O . TYR C 1 181 ? -14.234 85.128 17.725 1.00 17.61 ? 214 TYR C O 1 ATOM 8060 C CB . TYR C 1 181 ? -14.333 82.082 17.792 1.00 17.31 ? 214 TYR C CB 1 ATOM 8061 C CG . TYR C 1 181 ? -12.926 81.576 17.942 1.00 16.74 ? 214 TYR C CG 1 ATOM 8062 C CD1 . TYR C 1 181 ? -12.342 81.448 19.176 1.00 16.37 ? 214 TYR C CD1 1 ATOM 8063 C CD2 . TYR C 1 181 ? -12.197 81.232 16.842 1.00 17.46 ? 214 TYR C CD2 1 ATOM 8064 C CE1 . TYR C 1 181 ? -11.078 80.989 19.320 1.00 17.43 ? 214 TYR C CE1 1 ATOM 8065 C CE2 . TYR C 1 181 ? -10.902 80.755 16.952 1.00 18.26 ? 214 TYR C CE2 1 ATOM 8066 C CZ . TYR C 1 181 ? -10.322 80.630 18.205 1.00 18.62 ? 214 TYR C CZ 1 ATOM 8067 O OH . TYR C 1 181 ? -9.013 80.102 18.361 1.00 17.10 ? 214 TYR C OH 1 ATOM 8068 N N . GLY C 1 182 ? -13.145 84.620 19.720 1.00 19.46 ? 215 GLY C N 1 ATOM 8069 C CA . GLY C 1 182 ? -12.312 85.822 19.810 1.00 21.29 ? 215 GLY C CA 1 ATOM 8070 C C . GLY C 1 182 ? -11.767 86.423 18.534 1.00 24.39 ? 215 GLY C C 1 ATOM 8071 O O . GLY C 1 182 ? -11.971 87.609 18.286 1.00 27.79 ? 215 GLY C O 1 ATOM 8072 N N . PRO C 1 183 ? -11.063 85.627 17.706 1.00 26.47 ? 216 PRO C N 1 ATOM 8073 C CA . PRO C 1 183 ? -10.542 86.139 16.405 1.00 27.01 ? 216 PRO C CA 1 ATOM 8074 C C . PRO C 1 183 ? -11.543 86.384 15.269 1.00 29.29 ? 216 PRO C C 1 ATOM 8075 O O . PRO C 1 183 ? -11.119 86.719 14.135 1.00 33.86 ? 216 PRO C O 1 ATOM 8076 C CB . PRO C 1 183 ? -9.528 85.037 15.956 1.00 26.46 ? 216 PRO C CB 1 ATOM 8077 C CG . PRO C 1 183 ? -9.293 84.163 17.139 1.00 25.74 ? 216 PRO C CG 1 ATOM 8078 C CD . PRO C 1 183 ? -10.477 84.319 18.075 1.00 25.90 ? 216 PRO C CD 1 ATOM 8079 N N . ASN C 1 184 ? -12.838 86.157 15.513 1.00 32.81 ? 217 ASN C N 1 ATOM 8080 C CA . ASN C 1 184 ? -13.885 86.266 14.447 1.00 30.97 ? 217 ASN C CA 1 ATOM 8081 C C . ASN C 1 184 ? -14.283 87.726 14.301 1.00 29.22 ? 217 ASN C C 1 ATOM 8082 O O . ASN C 1 184 ? -15.047 88.245 15.082 1.00 25.17 ? 217 ASN C O 1 ATOM 8083 C CB . ASN C 1 184 ? -15.163 85.391 14.695 1.00 30.25 ? 217 ASN C CB 1 ATOM 8084 C CG . ASN C 1 184 ? -16.042 85.238 13.415 1.00 27.08 ? 217 ASN C CG 1 ATOM 8085 O OD1 . ASN C 1 184 ? -15.975 86.094 12.545 1.00 29.36 ? 217 ASN C OD1 1 ATOM 8086 N ND2 . ASN C 1 184 ? -16.825 84.153 13.292 1.00 22.54 ? 217 ASN C ND2 1 ATOM 8087 N N . ILE C 1 185 ? -13.726 88.354 13.281 1.00 30.92 ? 218 ILE C N 1 ATOM 8088 C CA . ILE C 1 185 ? -13.966 89.738 12.991 1.00 33.43 ? 218 ILE C CA 1 ATOM 8089 C C . ILE C 1 185 ? -15.370 89.931 12.421 1.00 31.19 ? 218 ILE C C 1 ATOM 8090 O O . ILE C 1 185 ? -15.915 91.003 12.582 1.00 38.95 ? 218 ILE C O 1 ATOM 8091 C CB . ILE C 1 185 ? -12.890 90.293 11.990 1.00 36.05 ? 218 ILE C CB 1 ATOM 8092 C CG1 . ILE C 1 185 ? -11.441 90.158 12.526 1.00 35.58 ? 218 ILE C CG1 1 ATOM 8093 C CG2 . ILE C 1 185 ? -13.176 91.737 11.631 1.00 38.58 ? 218 ILE C CG2 1 ATOM 8094 C CD1 . ILE C 1 185 ? -11.268 90.336 14.023 1.00 36.66 ? 218 ILE C CD1 1 ATOM 8095 N N . MET C 1 186 ? -15.966 88.932 11.784 1.00 26.41 ? 219 MET C N 1 ATOM 8096 C CA . MET C 1 186 ? -17.201 89.159 11.099 1.00 27.98 ? 219 MET C CA 1 ATOM 8097 C C . MET C 1 186 ? -18.342 89.408 12.061 1.00 31.70 ? 219 MET C C 1 ATOM 8098 O O . MET C 1 186 ? -19.436 89.849 11.694 1.00 33.99 ? 219 MET C O 1 ATOM 8099 C CB . MET C 1 186 ? -17.556 87.986 10.184 1.00 31.90 ? 219 MET C CB 1 ATOM 8100 C CG . MET C 1 186 ? -16.498 87.656 9.125 1.00 36.49 ? 219 MET C CG 1 ATOM 8101 S SD . MET C 1 186 ? -16.028 88.960 7.969 1.00 40.28 ? 219 MET C SD 1 ATOM 8102 C CE . MET C 1 186 ? -14.446 88.432 7.248 1.00 44.57 ? 219 MET C CE 1 ATOM 8103 N N . THR C 1 187 ? -18.125 89.112 13.322 1.00 33.04 ? 220 THR C N 1 ATOM 8104 C CA . THR C 1 187 ? -19.223 89.209 14.248 1.00 30.80 ? 220 THR C CA 1 ATOM 8105 C C . THR C 1 187 ? -19.013 90.322 15.313 1.00 32.00 ? 220 THR C C 1 ATOM 8106 O O . THR C 1 187 ? -19.846 90.478 16.232 1.00 29.61 ? 220 THR C O 1 ATOM 8107 C CB . THR C 1 187 ? -19.557 87.795 14.836 1.00 27.73 ? 220 THR C CB 1 ATOM 8108 O OG1 . THR C 1 187 ? -18.571 87.412 15.775 1.00 28.17 ? 220 THR C OG1 1 ATOM 8109 C CG2 . THR C 1 187 ? -19.628 86.775 13.763 1.00 25.07 ? 220 THR C CG2 1 ATOM 8110 N N . LEU C 1 188 ? -17.949 91.124 15.171 1.00 34.82 ? 221 LEU C N 1 ATOM 8111 C CA . LEU C 1 188 ? -17.693 92.229 16.120 1.00 36.92 ? 221 LEU C CA 1 ATOM 8112 C C . LEU C 1 188 ? -18.876 93.199 16.217 1.00 37.27 ? 221 LEU C C 1 ATOM 8113 O O . LEU C 1 188 ? -19.522 93.526 15.222 1.00 35.41 ? 221 LEU C O 1 ATOM 8114 C CB . LEU C 1 188 ? -16.422 93.007 15.761 1.00 38.92 ? 221 LEU C CB 1 ATOM 8115 C CG . LEU C 1 188 ? -15.158 92.408 16.364 1.00 40.70 ? 221 LEU C CG 1 ATOM 8116 C CD1 . LEU C 1 188 ? -13.955 92.848 15.560 1.00 43.61 ? 221 LEU C CD1 1 ATOM 8117 C CD2 . LEU C 1 188 ? -14.999 92.797 17.823 1.00 38.75 ? 221 LEU C CD2 1 ATOM 8118 N N . ASN C 1 189 ? -19.144 93.617 17.449 1.00 40.54 ? 222 ASN C N 1 ATOM 8119 C CA . ASN C 1 189 ? -20.229 94.522 17.827 1.00 42.74 ? 222 ASN C CA 1 ATOM 8120 C C . ASN C 1 189 ? -21.650 94.048 17.473 1.00 40.84 ? 222 ASN C C 1 ATOM 8121 O O . ASN C 1 189 ? -22.605 94.800 17.627 1.00 44.79 ? 222 ASN C O 1 ATOM 8122 C CB . ASN C 1 189 ? -19.954 95.955 17.322 1.00 45.74 ? 222 ASN C CB 1 ATOM 8123 C CG . ASN C 1 189 ? -20.262 97.001 18.382 1.00 54.63 ? 222 ASN C CG 1 ATOM 8124 O OD1 . ASN C 1 189 ? -19.876 96.850 19.555 1.00 55.26 ? 222 ASN C OD1 1 ATOM 8125 N ND2 . ASN C 1 189 ? -20.976 98.063 17.990 1.00 61.35 ? 222 ASN C ND2 1 ATOM 8126 N N . LYS C 1 190 ? -21.784 92.795 17.042 1.00 39.94 ? 223 LYS C N 1 ATOM 8127 C CA . LYS C 1 190 ? -23.104 92.102 16.910 1.00 37.15 ? 223 LYS C CA 1 ATOM 8128 C C . LYS C 1 190 ? -23.606 91.464 18.213 1.00 33.32 ? 223 LYS C C 1 ATOM 8129 O O . LYS C 1 190 ? -22.883 90.753 18.901 1.00 28.61 ? 223 LYS C O 1 ATOM 8130 C CB . LYS C 1 190 ? -23.060 91.018 15.841 1.00 33.80 ? 223 LYS C CB 1 ATOM 8131 C CG . LYS C 1 190 ? -22.774 91.578 14.460 1.00 33.58 ? 223 LYS C CG 1 ATOM 8132 C CD . LYS C 1 190 ? -23.107 90.565 13.381 1.00 33.49 ? 223 LYS C CD 1 ATOM 8133 C CE . LYS C 1 190 ? -22.742 91.033 11.997 1.00 30.91 ? 223 LYS C CE 1 ATOM 8134 N NZ . LYS C 1 190 ? -23.855 91.897 11.583 1.00 32.37 1 223 LYS C NZ 1 ATOM 8135 N N . THR C 1 191 ? -24.870 91.738 18.496 1.00 35.38 ? 224 THR C N 1 ATOM 8136 C CA . THR C 1 191 ? -25.513 91.420 19.773 1.00 36.87 ? 224 THR C CA 1 ATOM 8137 C C . THR C 1 191 ? -25.977 89.964 19.770 1.00 34.42 ? 224 THR C C 1 ATOM 8138 O O . THR C 1 191 ? -25.849 89.268 20.763 1.00 32.79 ? 224 THR C O 1 ATOM 8139 C CB . THR C 1 191 ? -26.723 92.361 20.058 1.00 37.86 ? 224 THR C CB 1 ATOM 8140 O OG1 . THR C 1 191 ? -27.147 92.170 21.401 1.00 39.58 ? 224 THR C OG1 1 ATOM 8141 C CG2 . THR C 1 191 ? -27.937 92.110 19.116 1.00 38.90 ? 224 THR C CG2 1 ATOM 8142 N N . ASP C 1 192 ? -26.488 89.518 18.626 1.00 32.93 ? 225 ASP C N 1 ATOM 8143 C CA . ASP C 1 192 ? -26.901 88.145 18.454 1.00 29.54 ? 225 ASP C CA 1 ATOM 8144 C C . ASP C 1 192 ? -26.589 87.702 17.021 1.00 29.58 ? 225 ASP C C 1 ATOM 8145 O O . ASP C 1 192 ? -27.474 87.659 16.176 1.00 31.74 ? 225 ASP C O 1 ATOM 8146 C CB . ASP C 1 192 ? -28.389 87.995 18.805 1.00 26.87 ? 225 ASP C CB 1 ATOM 8147 C CG . ASP C 1 192 ? -28.870 86.585 18.678 1.00 25.31 ? 225 ASP C CG 1 ATOM 8148 O OD1 . ASP C 1 192 ? -27.987 85.729 18.528 1.00 24.92 ? 225 ASP C OD1 1 ATOM 8149 O OD2 . ASP C 1 192 ? -30.097 86.310 18.694 1.00 24.42 -1 225 ASP C OD2 1 ATOM 8150 N N . PRO C 1 193 ? -25.317 87.356 16.744 1.00 30.34 ? 226 PRO C N 1 ATOM 8151 C CA . PRO C 1 193 ? -24.904 86.792 15.431 1.00 29.09 ? 226 PRO C CA 1 ATOM 8152 C C . PRO C 1 193 ? -25.724 85.601 14.900 1.00 25.01 ? 226 PRO C C 1 ATOM 8153 O O . PRO C 1 193 ? -25.881 84.554 15.560 1.00 21.75 ? 226 PRO C O 1 ATOM 8154 C CB . PRO C 1 193 ? -23.453 86.355 15.663 1.00 31.29 ? 226 PRO C CB 1 ATOM 8155 C CG . PRO C 1 193 ? -22.969 87.161 16.813 1.00 32.40 ? 226 PRO C CG 1 ATOM 8156 C CD . PRO C 1 193 ? -24.176 87.505 17.664 1.00 31.58 ? 226 PRO C CD 1 ATOM 8157 N N . ALA C 1 194 ? -26.218 85.819 13.688 1.00 24.65 ? 227 ALA C N 1 ATOM 8158 C CA . ALA C 1 194 ? -26.941 84.845 12.864 1.00 24.40 ? 227 ALA C CA 1 ATOM 8159 C C . ALA C 1 194 ? -28.219 84.426 13.605 1.00 23.32 ? 227 ALA C C 1 ATOM 8160 O O . ALA C 1 194 ? -28.911 83.465 13.253 1.00 19.52 ? 227 ALA C O 1 ATOM 8161 C CB . ALA C 1 194 ? -26.043 83.672 12.515 1.00 24.00 ? 227 ALA C CB 1 ATOM 8162 N N . ASN C 1 195 ? -28.510 85.214 14.623 1.00 25.00 ? 228 ASN C N 1 ATOM 8163 C CA . ASN C 1 195 ? -29.725 85.073 15.364 1.00 33.13 ? 228 ASN C CA 1 ATOM 8164 C C . ASN C 1 195 ? -29.752 83.810 16.224 1.00 34.43 ? 228 ASN C C 1 ATOM 8165 O O . ASN C 1 195 ? -30.811 83.255 16.522 1.00 35.43 ? 228 ASN C O 1 ATOM 8166 C CB . ASN C 1 195 ? -30.938 85.162 14.419 1.00 36.90 ? 228 ASN C CB 1 ATOM 8167 C CG . ASN C 1 195 ? -31.744 86.417 14.682 1.00 40.43 ? 228 ASN C CG 1 ATOM 8168 O OD1 . ASN C 1 195 ? -31.434 87.502 14.154 1.00 38.55 ? 228 ASN C OD1 1 ATOM 8169 N ND2 . ASN C 1 195 ? -32.769 86.289 15.550 1.00 42.28 ? 228 ASN C ND2 1 ATOM 8170 N N . GLN C 1 196 ? -28.561 83.378 16.625 1.00 32.30 ? 229 GLN C N 1 ATOM 8171 C CA . GLN C 1 196 ? -28.368 82.067 17.245 1.00 28.28 ? 229 GLN C CA 1 ATOM 8172 C C . GLN C 1 196 ? -28.948 82.037 18.618 1.00 23.60 ? 229 GLN C C 1 ATOM 8173 O O . GLN C 1 196 ? -29.517 81.083 19.049 1.00 21.52 ? 229 GLN C O 1 ATOM 8174 C CB . GLN C 1 196 ? -26.862 81.724 17.304 1.00 27.08 ? 229 GLN C CB 1 ATOM 8175 C CG . GLN C 1 196 ? -26.550 80.283 17.657 1.00 23.47 ? 229 GLN C CG 1 ATOM 8176 C CD . GLN C 1 196 ? -25.147 79.868 17.271 1.00 21.55 ? 229 GLN C CD 1 ATOM 8177 O OE1 . GLN C 1 196 ? -24.110 80.369 17.785 1.00 20.09 ? 229 GLN C OE1 1 ATOM 8178 N NE2 . GLN C 1 196 ? -25.100 78.907 16.408 1.00 20.87 ? 229 GLN C NE2 1 ATOM 8179 N N . PHE C 1 197 ? -28.797 83.116 19.315 1.00 25.97 ? 230 PHE C N 1 ATOM 8180 C CA . PHE C 1 197 ? -29.237 83.134 20.694 1.00 28.92 ? 230 PHE C CA 1 ATOM 8181 C C . PHE C 1 197 ? -30.755 82.998 20.702 1.00 32.16 ? 230 PHE C C 1 ATOM 8182 O O . PHE C 1 197 ? -31.282 82.110 21.375 1.00 35.79 ? 230 PHE C O 1 ATOM 8183 C CB . PHE C 1 197 ? -28.753 84.406 21.413 1.00 27.60 ? 230 PHE C CB 1 ATOM 8184 C CG . PHE C 1 197 ? -27.245 84.475 21.605 1.00 28.01 ? 230 PHE C CG 1 ATOM 8185 C CD1 . PHE C 1 197 ? -26.544 83.417 22.169 1.00 29.00 ? 230 PHE C CD1 1 ATOM 8186 C CD2 . PHE C 1 197 ? -26.540 85.629 21.287 1.00 29.72 ? 230 PHE C CD2 1 ATOM 8187 C CE1 . PHE C 1 197 ? -25.173 83.504 22.385 1.00 30.53 ? 230 PHE C CE1 1 ATOM 8188 C CE2 . PHE C 1 197 ? -25.159 85.716 21.481 1.00 31.17 ? 230 PHE C CE2 1 ATOM 8189 C CZ . PHE C 1 197 ? -24.474 84.654 22.038 1.00 29.89 ? 230 PHE C CZ 1 ATOM 8190 N N . GLU C 1 198 ? -31.435 83.842 19.917 1.00 33.63 ? 231 GLU C N 1 ATOM 8191 C CA . GLU C 1 198 ? -32.899 83.858 19.806 1.00 32.07 ? 231 GLU C CA 1 ATOM 8192 C C . GLU C 1 198 ? -33.466 82.562 19.267 1.00 27.65 ? 231 GLU C C 1 ATOM 8193 O O . GLU C 1 198 ? -34.476 82.073 19.744 1.00 27.39 ? 231 GLU C O 1 ATOM 8194 C CB . GLU C 1 198 ? -33.304 84.996 18.898 1.00 37.73 ? 231 GLU C CB 1 ATOM 8195 C CG . GLU C 1 198 ? -34.796 85.229 18.744 1.00 44.32 ? 231 GLU C CG 1 ATOM 8196 C CD . GLU C 1 198 ? -35.106 86.456 17.875 1.00 51.46 ? 231 GLU C CD 1 ATOM 8197 O OE1 . GLU C 1 198 ? -34.334 87.475 17.914 1.00 52.60 ? 231 GLU C OE1 1 ATOM 8198 O OE2 . GLU C 1 198 ? -36.134 86.394 17.152 1.00 52.38 -1 231 GLU C OE2 1 ATOM 8199 N N . TRP C 1 199 ? -32.824 82.013 18.255 1.00 25.72 ? 232 TRP C N 1 ATOM 8200 C CA . TRP C 1 199 ? -33.149 80.667 17.774 1.00 24.63 ? 232 TRP C CA 1 ATOM 8201 C C . TRP C 1 199 ? -32.766 79.534 18.802 1.00 25.04 ? 232 TRP C C 1 ATOM 8202 O O . TRP C 1 199 ? -33.538 78.562 18.927 1.00 23.60 ? 232 TRP C O 1 ATOM 8203 C CB . TRP C 1 199 ? -32.482 80.425 16.434 1.00 24.13 ? 232 TRP C CB 1 ATOM 8204 C CG . TRP C 1 199 ? -32.537 79.036 15.960 1.00 23.03 ? 232 TRP C CG 1 ATOM 8205 C CD1 . TRP C 1 199 ? -33.408 78.554 15.132 1.00 22.91 ? 232 TRP C CD1 1 ATOM 8206 C CD2 . TRP C 1 199 ? -31.670 77.952 16.323 1.00 24.97 ? 232 TRP C CD2 1 ATOM 8207 N NE1 . TRP C 1 199 ? -33.178 77.241 14.896 1.00 23.50 ? 232 TRP C NE1 1 ATOM 8208 C CE2 . TRP C 1 199 ? -32.103 76.837 15.620 1.00 23.98 ? 232 TRP C CE2 1 ATOM 8209 C CE3 . TRP C 1 199 ? -30.549 77.825 17.167 1.00 26.95 ? 232 TRP C CE3 1 ATOM 8210 C CZ2 . TRP C 1 199 ? -31.474 75.577 15.721 1.00 25.40 ? 232 TRP C CZ2 1 ATOM 8211 C CZ3 . TRP C 1 199 ? -29.917 76.575 17.263 1.00 25.15 ? 232 TRP C CZ3 1 ATOM 8212 C CH2 . TRP C 1 199 ? -30.391 75.474 16.558 1.00 25.25 ? 232 TRP C CH2 1 ATOM 8213 N N . LEU C 1 200 ? -31.612 79.645 19.498 1.00 23.42 ? 233 LEU C N 1 ATOM 8214 C CA . LEU C 1 200 ? -31.258 78.719 20.629 1.00 24.07 ? 233 LEU C CA 1 ATOM 8215 C C . LEU C 1 200 ? -32.409 78.602 21.691 1.00 25.60 ? 233 LEU C C 1 ATOM 8216 O O . LEU C 1 200 ? -32.959 77.500 21.955 1.00 22.13 ? 233 LEU C O 1 ATOM 8217 C CB . LEU C 1 200 ? -29.913 79.107 21.336 1.00 20.77 ? 233 LEU C CB 1 ATOM 8218 C CG . LEU C 1 200 ? -29.426 78.185 22.446 1.00 18.46 ? 233 LEU C CG 1 ATOM 8219 C CD1 . LEU C 1 200 ? -29.497 76.740 21.997 1.00 20.43 ? 233 LEU C CD1 1 ATOM 8220 C CD2 . LEU C 1 200 ? -28.013 78.418 22.869 1.00 17.54 ? 233 LEU C CD2 1 ATOM 8221 N N . GLU C 1 201 ? -32.767 79.763 22.247 1.00 30.19 ? 234 GLU C N 1 ATOM 8222 C CA . GLU C 1 201 ? -33.787 79.893 23.301 1.00 33.63 ? 234 GLU C CA 1 ATOM 8223 C C . GLU C 1 201 ? -35.112 79.346 22.806 1.00 33.05 ? 234 GLU C C 1 ATOM 8224 O O . GLU C 1 201 ? -35.847 78.632 23.503 1.00 33.80 ? 234 GLU C O 1 ATOM 8225 C CB . GLU C 1 201 ? -33.987 81.357 23.691 1.00 35.54 ? 234 GLU C CB 1 ATOM 8226 C CG . GLU C 1 201 ? -32.870 81.928 24.549 1.00 42.36 ? 234 GLU C CG 1 ATOM 8227 C CD . GLU C 1 201 ? -33.304 83.139 25.377 1.00 48.85 ? 234 GLU C CD 1 ATOM 8228 O OE1 . GLU C 1 201 ? -32.820 84.276 25.079 1.00 52.96 ? 234 GLU C OE1 1 ATOM 8229 O OE2 . GLU C 1 201 ? -34.128 82.938 26.320 1.00 51.95 -1 234 GLU C OE2 1 ATOM 8230 N N . SER C 1 202 ? -35.426 79.703 21.585 1.00 30.20 ? 235 SER C N 1 ATOM 8231 C CA . SER C 1 202 ? -36.670 79.297 21.079 1.00 28.50 ? 235 SER C CA 1 ATOM 8232 C C . SER C 1 202 ? -36.600 77.781 20.930 1.00 26.02 ? 235 SER C C 1 ATOM 8233 O O . SER C 1 202 ? -37.540 77.106 21.258 1.00 26.18 ? 235 SER C O 1 ATOM 8234 C CB . SER C 1 202 ? -36.997 80.026 19.788 1.00 27.59 ? 235 SER C CB 1 ATOM 8235 O OG . SER C 1 202 ? -38.016 79.298 19.141 1.00 33.20 ? 235 SER C OG 1 ATOM 8236 N N . THR C 1 203 ? -35.484 77.247 20.459 1.00 25.72 ? 236 THR C N 1 ATOM 8237 C CA . THR C 1 203 ? -35.394 75.807 20.192 1.00 25.70 ? 236 THR C CA 1 ATOM 8238 C C . THR C 1 203 ? -35.462 75.115 21.555 1.00 26.03 ? 236 THR C C 1 ATOM 8239 O O . THR C 1 203 ? -36.086 74.054 21.716 1.00 24.83 ? 236 THR C O 1 ATOM 8240 C CB . THR C 1 203 ? -34.103 75.399 19.413 1.00 24.80 ? 236 THR C CB 1 ATOM 8241 O OG1 . THR C 1 203 ? -34.123 75.911 18.081 1.00 22.07 ? 236 THR C OG1 1 ATOM 8242 C CG2 . THR C 1 203 ? -33.986 73.885 19.296 1.00 25.67 ? 236 THR C CG2 1 ATOM 8243 N N . LEU C 1 204 ? -34.828 75.722 22.548 1.00 27.37 ? 237 LEU C N 1 ATOM 8244 C CA . LEU C 1 204 ? -34.753 75.094 23.886 1.00 29.74 ? 237 LEU C CA 1 ATOM 8245 C C . LEU C 1 204 ? -36.144 74.983 24.544 1.00 31.58 ? 237 LEU C C 1 ATOM 8246 O O . LEU C 1 204 ? -36.467 73.958 25.164 1.00 29.48 ? 237 LEU C O 1 ATOM 8247 C CB . LEU C 1 204 ? -33.729 75.844 24.759 1.00 28.03 ? 237 LEU C CB 1 ATOM 8248 C CG . LEU C 1 204 ? -32.266 75.557 24.394 1.00 25.35 ? 237 LEU C CG 1 ATOM 8249 C CD1 . LEU C 1 204 ? -31.401 76.483 25.212 1.00 26.56 ? 237 LEU C CD1 1 ATOM 8250 C CD2 . LEU C 1 204 ? -31.870 74.121 24.656 1.00 24.50 ? 237 LEU C CD2 1 ATOM 8251 N N . ASN C 1 205 ? -36.931 76.050 24.362 1.00 34.90 ? 238 ASN C N 1 ATOM 8252 C CA . ASN C 1 205 ? -38.360 76.128 24.716 1.00 38.74 ? 238 ASN C CA 1 ATOM 8253 C C . ASN C 1 205 ? -39.221 75.048 24.031 1.00 35.54 ? 238 ASN C C 1 ATOM 8254 O O . ASN C 1 205 ? -39.907 74.296 24.702 1.00 36.82 ? 238 ASN C O 1 ATOM 8255 C CB . ASN C 1 205 ? -38.903 77.532 24.382 1.00 42.10 ? 238 ASN C CB 1 ATOM 8256 C CG . ASN C 1 205 ? -39.864 78.062 25.429 1.00 49.08 ? 238 ASN C CG 1 ATOM 8257 O OD1 . ASN C 1 205 ? -41.042 78.317 25.143 1.00 52.77 ? 238 ASN C OD1 1 ATOM 8258 N ND2 . ASN C 1 205 ? -39.366 78.245 26.652 1.00 52.63 ? 238 ASN C ND2 1 ATOM 8259 N N . ASN C 1 206 ? -39.182 74.976 22.707 1.00 35.27 ? 239 ASN C N 1 ATOM 8260 C CA . ASN C 1 206 ? -39.876 73.921 21.967 1.00 38.30 ? 239 ASN C CA 1 ATOM 8261 C C . ASN C 1 206 ? -39.637 72.594 22.618 1.00 37.71 ? 239 ASN C C 1 ATOM 8262 O O . ASN C 1 206 ? -40.568 71.850 22.869 1.00 39.29 ? 239 ASN C O 1 ATOM 8263 C CB . ASN C 1 206 ? -39.431 73.856 20.493 1.00 42.38 ? 239 ASN C CB 1 ATOM 8264 C CG . ASN C 1 206 ? -39.651 72.463 19.838 1.00 50.10 ? 239 ASN C CG 1 ATOM 8265 O OD1 . ASN C 1 206 ? -38.714 71.650 19.722 1.00 52.31 ? 239 ASN C OD1 1 ATOM 8266 N ND2 . ASN C 1 206 ? -40.873 72.210 19.358 1.00 49.18 ? 239 ASN C ND2 1 ATOM 8267 N N . SER C 1 207 ? -38.371 72.307 22.896 1.00 39.74 ? 240 SER C N 1 ATOM 8268 C CA . SER C 1 207 ? -37.952 70.991 23.416 1.00 38.59 ? 240 SER C CA 1 ATOM 8269 C C . SER C 1 207 ? -38.578 70.667 24.782 1.00 38.79 ? 240 SER C C 1 ATOM 8270 O O . SER C 1 207 ? -39.181 69.593 24.985 1.00 36.66 ? 240 SER C O 1 ATOM 8271 C CB . SER C 1 207 ? -36.415 70.908 23.501 1.00 35.79 ? 240 SER C CB 1 ATOM 8272 O OG . SER C 1 207 ? -35.818 70.946 22.211 1.00 33.94 ? 240 SER C OG 1 ATOM 8273 N N . GLN C 1 208 ? -38.429 71.619 25.690 1.00 38.80 ? 241 GLN C N 1 ATOM 8274 C CA . GLN C 1 208 ? -38.928 71.526 27.061 1.00 43.28 ? 241 GLN C CA 1 ATOM 8275 C C . GLN C 1 208 ? -40.403 71.211 27.156 1.00 47.50 ? 241 GLN C C 1 ATOM 8276 O O . GLN C 1 208 ? -40.842 70.583 28.119 1.00 50.23 ? 241 GLN C O 1 ATOM 8277 C CB . GLN C 1 208 ? -38.680 72.859 27.735 1.00 42.58 ? 241 GLN C CB 1 ATOM 8278 C CG . GLN C 1 208 ? -38.957 72.920 29.204 1.00 43.45 ? 241 GLN C CG 1 ATOM 8279 C CD . GLN C 1 208 ? -38.316 74.165 29.796 1.00 46.01 ? 241 GLN C CD 1 ATOM 8280 O OE1 . GLN C 1 208 ? -37.264 74.090 30.453 1.00 49.37 ? 241 GLN C OE1 1 ATOM 8281 N NE2 . GLN C 1 208 ? -38.919 75.326 29.533 1.00 42.49 ? 241 GLN C NE2 1 ATOM 8282 N N . GLN C 1 209 ? -41.149 71.674 26.154 1.00 51.36 ? 242 GLN C N 1 ATOM 8283 C CA . GLN C 1 209 ? -42.599 71.555 26.120 1.00 54.12 ? 242 GLN C CA 1 ATOM 8284 C C . GLN C 1 209 ? -43.071 70.369 25.344 1.00 48.79 ? 242 GLN C C 1 ATOM 8285 O O . GLN C 1 209 ? -44.210 69.990 25.479 1.00 49.96 ? 242 GLN C O 1 ATOM 8286 C CB . GLN C 1 209 ? -43.210 72.814 25.517 1.00 58.53 ? 242 GLN C CB 1 ATOM 8287 C CG . GLN C 1 209 ? -42.955 74.038 26.373 1.00 63.53 ? 242 GLN C CG 1 ATOM 8288 C CD . GLN C 1 209 ? -43.561 75.274 25.769 1.00 75.63 ? 242 GLN C CD 1 ATOM 8289 O OE1 . GLN C 1 209 ? -43.593 75.423 24.542 1.00 72.87 ? 242 GLN C OE1 1 ATOM 8290 N NE2 . GLN C 1 209 ? -44.064 76.174 26.623 1.00 84.16 ? 242 GLN C NE2 1 ATOM 8291 N N . ASN C 1 210 ? -42.198 69.803 24.519 1.00 48.25 ? 243 ASN C N 1 ATOM 8292 C CA . ASN C 1 210 ? -42.504 68.594 23.757 1.00 43.18 ? 243 ASN C CA 1 ATOM 8293 C C . ASN C 1 210 ? -41.899 67.355 24.387 1.00 42.01 ? 243 ASN C C 1 ATOM 8294 O O . ASN C 1 210 ? -41.657 66.353 23.692 1.00 39.55 ? 243 ASN C O 1 ATOM 8295 C CB . ASN C 1 210 ? -42.011 68.749 22.334 1.00 43.47 ? 243 ASN C CB 1 ATOM 8296 C CG . ASN C 1 210 ? -42.649 69.922 21.633 1.00 48.70 ? 243 ASN C CG 1 ATOM 8297 O OD1 . ASN C 1 210 ? -43.230 70.794 22.277 1.00 52.78 ? 243 ASN C OD1 1 ATOM 8298 N ND2 . ASN C 1 210 ? -42.559 69.948 20.300 1.00 57.34 ? 243 ASN C ND2 1 ATOM 8299 N N . LYS C 1 211 ? -41.669 67.415 25.701 1.00 40.11 ? 244 LYS C N 1 ATOM 8300 C CA . LYS C 1 211 ? -41.130 66.278 26.441 1.00 41.88 ? 244 LYS C CA 1 ATOM 8301 C C . LYS C 1 211 ? -39.857 65.766 25.774 1.00 37.93 ? 244 LYS C C 1 ATOM 8302 O O . LYS C 1 211 ? -39.693 64.579 25.595 1.00 40.01 ? 244 LYS C O 1 ATOM 8303 C CB . LYS C 1 211 ? -42.163 65.143 26.499 1.00 45.66 ? 244 LYS C CB 1 ATOM 8304 C CG . LYS C 1 211 ? -43.547 65.538 27.009 1.00 50.32 ? 244 LYS C CG 1 ATOM 8305 C CD . LYS C 1 211 ? -44.677 64.739 26.339 1.00 53.54 ? 244 LYS C CD 1 ATOM 8306 C CE . LYS C 1 211 ? -45.111 63.508 27.133 1.00 55.59 ? 244 LYS C CE 1 ATOM 8307 N NZ . LYS C 1 211 ? -45.871 62.525 26.292 1.00 56.82 1 244 LYS C NZ 1 ATOM 8308 N N . GLU C 1 212 ? -38.984 66.676 25.360 1.00 35.31 ? 245 GLU C N 1 ATOM 8309 C CA . GLU C 1 212 ? -37.738 66.302 24.712 1.00 31.81 ? 245 GLU C CA 1 ATOM 8310 C C . GLU C 1 212 ? -36.548 66.590 25.611 1.00 29.63 ? 245 GLU C C 1 ATOM 8311 O O . GLU C 1 212 ? -36.611 67.467 26.467 1.00 30.13 ? 245 GLU C O 1 ATOM 8312 C CB . GLU C 1 212 ? -37.552 67.070 23.403 1.00 32.48 ? 245 GLU C CB 1 ATOM 8313 C CG . GLU C 1 212 ? -38.371 66.556 22.235 1.00 31.76 ? 245 GLU C CG 1 ATOM 8314 C CD . GLU C 1 212 ? -38.204 67.379 20.975 1.00 32.04 ? 245 GLU C CD 1 ATOM 8315 O OE1 . GLU C 1 212 ? -37.794 68.556 21.050 1.00 27.98 ? 245 GLU C OE1 1 ATOM 8316 O OE2 . GLU C 1 212 ? -38.501 66.818 19.887 1.00 43.33 -1 245 GLU C OE2 1 ATOM 8317 N N . LYS C 1 213 ? -35.485 65.820 25.407 1.00 27.90 ? 246 LYS C N 1 ATOM 8318 C CA . LYS C 1 213 ? -34.162 66.114 25.938 1.00 27.18 ? 246 LYS C CA 1 ATOM 8319 C C . LYS C 1 213 ? -33.235 66.588 24.796 1.00 23.12 ? 246 LYS C C 1 ATOM 8320 O O . LYS C 1 213 ? -33.441 66.194 23.607 1.00 17.41 ? 246 LYS C O 1 ATOM 8321 C CB . LYS C 1 213 ? -33.540 64.879 26.578 1.00 30.07 ? 246 LYS C CB 1 ATOM 8322 C CG . LYS C 1 213 ? -34.453 64.108 27.505 1.00 33.87 ? 246 LYS C CG 1 ATOM 8323 C CD . LYS C 1 213 ? -34.961 64.972 28.634 1.00 35.94 ? 246 LYS C CD 1 ATOM 8324 C CE . LYS C 1 213 ? -33.854 65.299 29.596 1.00 39.07 ? 246 LYS C CE 1 ATOM 8325 N NZ . LYS C 1 213 ? -34.488 65.990 30.739 1.00 41.95 1 246 LYS C NZ 1 ATOM 8326 N N . VAL C 1 214 ? -32.225 67.385 25.207 1.00 19.26 ? 247 VAL C N 1 ATOM 8327 C CA . VAL C 1 214 ? -31.300 68.023 24.315 1.00 19.33 ? 247 VAL C CA 1 ATOM 8328 C C . VAL C 1 214 ? -29.847 67.694 24.623 1.00 19.94 ? 247 VAL C C 1 ATOM 8329 O O . VAL C 1 214 ? -29.449 67.687 25.818 1.00 18.96 ? 247 VAL C O 1 ATOM 8330 C CB . VAL C 1 214 ? -31.465 69.557 24.297 1.00 20.42 ? 247 VAL C CB 1 ATOM 8331 C CG1 . VAL C 1 214 ? -30.364 70.194 23.423 1.00 18.98 ? 247 VAL C CG1 1 ATOM 8332 C CG2 . VAL C 1 214 ? -32.894 69.943 23.811 1.00 19.44 ? 247 VAL C CG2 1 ATOM 8333 N N . TYR C 1 215 ? -29.096 67.350 23.537 1.00 19.26 ? 248 TYR C N 1 ATOM 8334 C CA . TYR C 1 215 ? -27.629 67.278 23.580 1.00 18.85 ? 248 TYR C CA 1 ATOM 8335 C C . TYR C 1 215 ? -27.130 68.458 22.816 1.00 19.65 ? 248 TYR C C 1 ATOM 8336 O O . TYR C 1 215 ? -27.447 68.606 21.648 1.00 24.19 ? 248 TYR C O 1 ATOM 8337 C CB . TYR C 1 215 ? -27.013 65.994 22.993 1.00 16.69 ? 248 TYR C CB 1 ATOM 8338 C CG . TYR C 1 215 ? -27.147 64.780 23.878 1.00 16.11 ? 248 TYR C CG 1 ATOM 8339 C CD1 . TYR C 1 215 ? -27.394 64.891 25.235 1.00 18.51 ? 248 TYR C CD1 1 ATOM 8340 C CD2 . TYR C 1 215 ? -27.008 63.529 23.376 1.00 16.34 ? 248 TYR C CD2 1 ATOM 8341 C CE1 . TYR C 1 215 ? -27.523 63.784 26.044 1.00 18.20 ? 248 TYR C CE1 1 ATOM 8342 C CE2 . TYR C 1 215 ? -27.146 62.394 24.165 1.00 17.23 ? 248 TYR C CE2 1 ATOM 8343 C CZ . TYR C 1 215 ? -27.409 62.545 25.496 1.00 18.09 ? 248 TYR C CZ 1 ATOM 8344 O OH . TYR C 1 215 ? -27.596 61.440 26.291 1.00 21.86 ? 248 TYR C OH 1 ATOM 8345 N N . ILE C 1 216 ? -26.371 69.319 23.497 1.00 18.40 ? 249 ILE C N 1 ATOM 8346 C CA . ILE C 1 216 ? -25.683 70.438 22.860 1.00 15.56 ? 249 ILE C CA 1 ATOM 8347 C C . ILE C 1 216 ? -24.343 69.987 22.310 1.00 15.05 ? 249 ILE C C 1 ATOM 8348 O O . ILE C 1 216 ? -23.521 69.403 23.040 1.00 14.36 ? 249 ILE C O 1 ATOM 8349 C CB . ILE C 1 216 ? -25.366 71.545 23.818 1.00 14.92 ? 249 ILE C CB 1 ATOM 8350 C CG1 . ILE C 1 216 ? -26.628 71.913 24.592 1.00 14.81 ? 249 ILE C CG1 1 ATOM 8351 C CG2 . ILE C 1 216 ? -24.752 72.713 23.019 1.00 15.63 ? 249 ILE C CG2 1 ATOM 8352 C CD1 . ILE C 1 216 ? -27.551 72.826 23.814 1.00 15.61 ? 249 ILE C CD1 1 ATOM 8353 N N A ILE C 1 217 ? -24.107 70.276 21.031 0.50 13.94 ? 250 ILE C N 1 ATOM 8354 N N B ILE C 1 217 ? -24.174 70.193 20.998 0.50 15.02 ? 250 ILE C N 1 ATOM 8355 C CA A ILE C 1 217 ? -22.830 69.989 20.415 0.50 13.12 ? 250 ILE C CA 1 ATOM 8356 C CA B ILE C 1 217 ? -22.897 70.025 20.336 0.50 14.77 ? 250 ILE C CA 1 ATOM 8357 C C A ILE C 1 217 ? -22.408 71.243 19.637 0.50 13.49 ? 250 ILE C C 1 ATOM 8358 C C B ILE C 1 217 ? -22.432 71.380 19.811 0.50 14.50 ? 250 ILE C C 1 ATOM 8359 O O A ILE C 1 217 ? -23.248 71.947 19.092 0.50 12.95 ? 250 ILE C O 1 ATOM 8360 O O B ILE C 1 217 ? -23.256 72.280 19.640 0.50 13.94 ? 250 ILE C O 1 ATOM 8361 C CB A ILE C 1 217 ? -22.906 68.674 19.610 0.50 12.04 ? 250 ILE C CB 1 ATOM 8362 C CB B ILE C 1 217 ? -22.943 68.975 19.215 0.50 14.91 ? 250 ILE C CB 1 ATOM 8363 C CG1 A ILE C 1 217 ? -23.808 68.801 18.370 0.50 11.97 ? 250 ILE C CG1 1 ATOM 8364 C CG1 B ILE C 1 217 ? -21.554 68.528 18.989 0.50 14.90 ? 250 ILE C CG1 1 ATOM 8365 C CG2 A ILE C 1 217 ? -23.495 67.599 20.485 0.50 11.38 ? 250 ILE C CG2 1 ATOM 8366 C CG2 B ILE C 1 217 ? -23.350 69.526 17.858 0.50 14.92 ? 250 ILE C CG2 1 ATOM 8367 C CD1 A ILE C 1 217 ? -23.177 68.558 17.008 0.50 11.25 ? 250 ILE C CD1 1 ATOM 8368 C CD1 B ILE C 1 217 ? -20.967 68.133 20.298 0.50 15.21 ? 250 ILE C CD1 1 ATOM 8369 N N . ALA C 1 218 ? -21.104 71.542 19.669 1.00 14.40 ? 251 ALA C N 1 ATOM 8370 C CA . ALA C 1 218 ? -20.474 72.728 18.992 1.00 13.99 ? 251 ALA C CA 1 ATOM 8371 C C . ALA C 1 218 ? -18.961 72.599 19.010 1.00 13.26 ? 251 ALA C C 1 ATOM 8372 O O . ALA C 1 218 ? -18.451 71.710 19.638 1.00 11.85 ? 251 ALA C O 1 ATOM 8373 C CB . ALA C 1 218 ? -20.906 74.022 19.630 1.00 14.35 ? 251 ALA C CB 1 ATOM 8374 N N . HIS C 1 219 ? -18.246 73.461 18.286 1.00 14.62 ? 252 HIS C N 1 ATOM 8375 C CA . HIS C 1 219 ? -16.735 73.541 18.342 1.00 14.84 ? 252 HIS C CA 1 ATOM 8376 C C . HIS C 1 219 ? -16.023 74.222 19.532 1.00 14.45 ? 252 HIS C C 1 ATOM 8377 O O . HIS C 1 219 ? -15.403 73.589 20.355 1.00 13.22 ? 252 HIS C O 1 ATOM 8378 C CB . HIS C 1 219 ? -16.166 74.242 17.115 1.00 15.40 ? 252 HIS C CB 1 ATOM 8379 C CG . HIS C 1 219 ? -14.735 73.925 16.893 1.00 15.36 ? 252 HIS C CG 1 ATOM 8380 N ND1 . HIS C 1 219 ? -14.302 72.649 16.558 1.00 16.75 ? 252 HIS C ND1 1 ATOM 8381 C CD2 . HIS C 1 219 ? -13.637 74.682 16.968 1.00 15.69 ? 252 HIS C CD2 1 ATOM 8382 C CE1 . HIS C 1 219 ? -12.994 72.633 16.429 1.00 15.59 ? 252 HIS C CE1 1 ATOM 8383 N NE2 . HIS C 1 219 ? -12.567 73.858 16.674 1.00 17.37 ? 252 HIS C NE2 1 ATOM 8384 N N . VAL C 1 220 ? -16.072 75.540 19.576 1.00 16.32 ? 253 VAL C N 1 ATOM 8385 C CA . VAL C 1 220 ? -15.454 76.292 20.679 1.00 16.39 ? 253 VAL C CA 1 ATOM 8386 C C . VAL C 1 220 ? -16.331 76.118 21.876 1.00 16.01 ? 253 VAL C C 1 ATOM 8387 O O . VAL C 1 220 ? -17.521 76.506 21.780 1.00 17.39 ? 253 VAL C O 1 ATOM 8388 C CB . VAL C 1 220 ? -15.492 77.788 20.390 1.00 18.09 ? 253 VAL C CB 1 ATOM 8389 C CG1 . VAL C 1 220 ? -14.647 78.571 21.431 1.00 18.55 ? 253 VAL C CG1 1 ATOM 8390 C CG2 . VAL C 1 220 ? -15.040 78.018 18.937 1.00 18.79 ? 253 VAL C CG2 1 ATOM 8391 N N . PRO C 1 221 ? -15.786 75.586 22.998 1.00 14.49 ? 254 PRO C N 1 ATOM 8392 C CA . PRO C 1 221 ? -16.547 75.495 24.176 1.00 14.65 ? 254 PRO C CA 1 ATOM 8393 C C . PRO C 1 221 ? -16.722 76.836 24.898 1.00 16.16 ? 254 PRO C C 1 ATOM 8394 O O . PRO C 1 221 ? -15.950 77.805 24.667 1.00 16.35 ? 254 PRO C O 1 ATOM 8395 C CB . PRO C 1 221 ? -15.764 74.486 24.996 1.00 14.64 ? 254 PRO C CB 1 ATOM 8396 C CG . PRO C 1 221 ? -14.389 74.845 24.704 1.00 14.87 ? 254 PRO C CG 1 ATOM 8397 C CD . PRO C 1 221 ? -14.383 75.294 23.281 1.00 15.45 ? 254 PRO C CD 1 ATOM 8398 N N . VAL C 1 222 ? -17.769 76.900 25.735 1.00 17.39 ? 255 VAL C N 1 ATOM 8399 C CA . VAL C 1 222 ? -17.953 78.033 26.654 1.00 18.84 ? 255 VAL C CA 1 ATOM 8400 C C . VAL C 1 222 ? -16.948 78.000 27.799 1.00 19.70 ? 255 VAL C C 1 ATOM 8401 O O . VAL C 1 222 ? -16.179 77.012 27.914 1.00 22.26 ? 255 VAL C O 1 ATOM 8402 C CB . VAL C 1 222 ? -19.314 77.961 27.297 1.00 19.37 ? 255 VAL C CB 1 ATOM 8403 C CG1 . VAL C 1 222 ? -20.380 78.256 26.265 1.00 19.57 ? 255 VAL C CG1 1 ATOM 8404 C CG2 . VAL C 1 222 ? -19.533 76.595 27.950 1.00 18.59 ? 255 VAL C CG2 1 ATOM 8405 N N . GLY C 1 223 ? -16.937 79.029 28.643 1.00 17.82 ? 256 GLY C N 1 ATOM 8406 C CA . GLY C 1 223 ? -16.144 78.951 29.866 1.00 18.68 ? 256 GLY C CA 1 ATOM 8407 C C . GLY C 1 223 ? -14.680 79.250 29.626 1.00 20.84 ? 256 GLY C C 1 ATOM 8408 O O . GLY C 1 223 ? -14.306 79.719 28.555 1.00 18.65 ? 256 GLY C O 1 ATOM 8409 N N . TYR C 1 224 ? -13.849 78.939 30.628 1.00 25.76 ? 257 TYR C N 1 ATOM 8410 C CA . TYR C 1 224 ? -12.393 79.274 30.637 1.00 29.33 ? 257 TYR C CA 1 ATOM 8411 C C . TYR C 1 224 ? -11.433 78.100 30.212 1.00 31.22 ? 257 TYR C C 1 ATOM 8412 O O . TYR C 1 224 ? -11.718 76.904 30.435 1.00 24.82 ? 257 TYR C O 1 ATOM 8413 C CB . TYR C 1 224 ? -11.997 79.903 32.016 1.00 28.75 ? 257 TYR C CB 1 ATOM 8414 C CG . TYR C 1 224 ? -12.602 81.301 32.198 1.00 29.65 ? 257 TYR C CG 1 ATOM 8415 C CD1 . TYR C 1 224 ? -13.957 81.456 32.464 1.00 30.46 ? 257 TYR C CD1 1 ATOM 8416 C CD2 . TYR C 1 224 ? -11.837 82.470 32.011 1.00 29.53 ? 257 TYR C CD2 1 ATOM 8417 C CE1 . TYR C 1 224 ? -14.531 82.697 32.562 1.00 30.64 ? 257 TYR C CE1 1 ATOM 8418 C CE2 . TYR C 1 224 ? -12.411 83.717 32.106 1.00 28.21 ? 257 TYR C CE2 1 ATOM 8419 C CZ . TYR C 1 224 ? -13.754 83.814 32.388 1.00 32.74 ? 257 TYR C CZ 1 ATOM 8420 O OH . TYR C 1 224 ? -14.380 85.040 32.520 1.00 43.90 ? 257 TYR C OH 1 ATOM 8421 N N . LEU C 1 225 ? -10.325 78.503 29.564 1.00 35.67 ? 258 LEU C N 1 ATOM 8422 C CA . LEU C 1 225 ? -9.247 77.578 29.082 1.00 40.97 ? 258 LEU C CA 1 ATOM 8423 C C . LEU C 1 225 ? -8.362 77.032 30.203 1.00 41.14 ? 258 LEU C C 1 ATOM 8424 O O . LEU C 1 225 ? -7.814 77.781 31.018 1.00 41.95 ? 258 LEU C O 1 ATOM 8425 C CB . LEU C 1 225 ? -8.328 78.239 28.027 1.00 39.55 ? 258 LEU C CB 1 ATOM 8426 C CG . LEU C 1 225 ? -8.895 78.516 26.630 1.00 41.34 ? 258 LEU C CG 1 ATOM 8427 C CD1 . LEU C 1 225 ? -7.814 78.857 25.611 1.00 41.36 ? 258 LEU C CD1 1 ATOM 8428 C CD2 . LEU C 1 225 ? -9.724 77.331 26.127 1.00 45.08 ? 258 LEU C CD2 1 ATOM 8429 N N . PRO C 1 226 ? -8.175 75.710 30.245 1.00 40.73 ? 259 PRO C N 1 ATOM 8430 C CA . PRO C 1 226 ? -7.680 75.320 31.557 1.00 39.94 ? 259 PRO C CA 1 ATOM 8431 C C . PRO C 1 226 ? -6.173 75.607 31.757 1.00 37.71 ? 259 PRO C C 1 ATOM 8432 O O . PRO C 1 226 ? -5.630 75.445 32.852 1.00 32.61 ? 259 PRO C O 1 ATOM 8433 C CB . PRO C 1 226 ? -8.029 73.811 31.592 1.00 38.36 ? 259 PRO C CB 1 ATOM 8434 C CG . PRO C 1 226 ? -8.979 73.579 30.461 1.00 34.78 ? 259 PRO C CG 1 ATOM 8435 C CD . PRO C 1 226 ? -8.516 74.534 29.431 1.00 37.94 ? 259 PRO C CD 1 ATOM 8436 N N A SER C 1 227 ? -5.464 76.017 30.716 0.50 37.41 ? 260 SER C N 1 ATOM 8437 N N B SER C 1 227 ? -5.572 76.076 30.661 0.50 38.17 ? 260 SER C N 1 ATOM 8438 C CA A SER C 1 227 ? -4.016 76.140 30.877 0.50 36.18 ? 260 SER C CA 1 ATOM 8439 C CA B SER C 1 227 ? -4.136 76.175 30.466 0.50 37.47 ? 260 SER C CA 1 ATOM 8440 C C A SER C 1 227 ? -3.531 77.562 30.988 0.50 38.24 ? 260 SER C C 1 ATOM 8441 C C B SER C 1 227 ? -3.583 77.514 30.929 0.50 39.05 ? 260 SER C C 1 ATOM 8442 O O A SER C 1 227 ? -2.323 77.776 31.187 0.50 35.39 ? 260 SER C O 1 ATOM 8443 O O B SER C 1 227 ? -2.399 77.617 31.301 0.50 35.62 ? 260 SER C O 1 ATOM 8444 C CB A SER C 1 227 ? -3.264 75.395 29.783 0.50 32.43 ? 260 SER C CB 1 ATOM 8445 C CB B SER C 1 227 ? -3.837 76.002 28.967 0.50 35.40 ? 260 SER C CB 1 ATOM 8446 O OG A SER C 1 227 ? -3.133 74.054 30.160 0.50 27.59 ? 260 SER C OG 1 ATOM 8447 O OG B SER C 1 227 ? -4.554 76.939 28.167 0.50 30.19 ? 260 SER C OG 1 ATOM 8448 N N . SER C 1 228 ? -4.464 78.518 30.892 1.00 41.55 ? 261 SER C N 1 ATOM 8449 C CA . SER C 1 228 ? -4.117 79.961 31.011 1.00 44.34 ? 261 SER C CA 1 ATOM 8450 C C . SER C 1 228 ? -5.006 80.707 32.054 1.00 50.11 ? 261 SER C C 1 ATOM 8451 O O . SER C 1 228 ? -6.011 80.177 32.580 1.00 52.25 ? 261 SER C O 1 ATOM 8452 C CB . SER C 1 228 ? -4.186 80.626 29.615 1.00 40.88 ? 261 SER C CB 1 ATOM 8453 O OG . SER C 1 228 ? -3.472 79.861 28.637 1.00 41.24 ? 261 SER C OG 1 ATOM 8454 N N . GLN C 1 229 ? -4.630 81.940 32.373 1.00 53.87 ? 262 GLN C N 1 ATOM 8455 C CA . GLN C 1 229 ? -5.372 82.685 33.384 1.00 56.07 ? 262 GLN C CA 1 ATOM 8456 C C . GLN C 1 229 ? -6.263 83.721 32.712 1.00 48.07 ? 262 GLN C C 1 ATOM 8457 O O . GLN C 1 229 ? -5.787 84.583 31.992 1.00 45.94 ? 262 GLN C O 1 ATOM 8458 C CB . GLN C 1 229 ? -4.431 83.291 34.468 1.00 59.99 ? 262 GLN C CB 1 ATOM 8459 C CG . GLN C 1 229 ? -4.347 84.813 34.556 1.00 62.13 ? 262 GLN C CG 1 ATOM 8460 C CD . GLN C 1 229 ? -4.005 85.314 35.949 1.00 65.61 ? 262 GLN C CD 1 ATOM 8461 O OE1 . GLN C 1 229 ? -4.505 86.363 36.371 1.00 67.39 ? 262 GLN C OE1 1 ATOM 8462 N NE2 . GLN C 1 229 ? -3.157 84.575 36.671 1.00 64.67 ? 262 GLN C NE2 1 ATOM 8463 N N . ASN C 1 230 ? -7.561 83.597 32.957 1.00 46.29 ? 263 ASN C N 1 ATOM 8464 C CA . ASN C 1 230 ? -8.551 84.593 32.569 1.00 46.18 ? 263 ASN C CA 1 ATOM 8465 C C . ASN C 1 230 ? -8.731 84.772 31.050 1.00 45.03 ? 263 ASN C C 1 ATOM 8466 O O . ASN C 1 230 ? -9.145 85.859 30.630 1.00 47.33 ? 263 ASN C O 1 ATOM 8467 C CB . ASN C 1 230 ? -8.261 85.952 33.263 1.00 48.39 ? 263 ASN C CB 1 ATOM 8468 C CG . ASN C 1 230 ? -9.482 86.893 33.297 1.00 49.33 ? 263 ASN C CG 1 ATOM 8469 O OD1 . ASN C 1 230 ? -9.343 88.128 33.306 1.00 49.60 ? 263 ASN C OD1 1 ATOM 8470 N ND2 . ASN C 1 230 ? -10.682 86.315 33.304 1.00 50.04 ? 263 ASN C ND2 1 ATOM 8471 N N . ILE C 1 231 ? -8.433 83.725 30.254 1.00 41.75 ? 264 ILE C N 1 ATOM 8472 C CA . ILE C 1 231 ? -8.824 83.646 28.824 1.00 40.01 ? 264 ILE C CA 1 ATOM 8473 C C . ILE C 1 231 ? -9.999 82.670 28.615 1.00 34.50 ? 264 ILE C C 1 ATOM 8474 O O . ILE C 1 231 ? -9.856 81.448 28.757 1.00 30.95 ? 264 ILE C O 1 ATOM 8475 C CB . ILE C 1 231 ? -7.669 83.216 27.839 1.00 46.00 ? 264 ILE C CB 1 ATOM 8476 C CG1 . ILE C 1 231 ? -6.302 83.803 28.237 1.00 48.82 ? 264 ILE C CG1 1 ATOM 8477 C CG2 . ILE C 1 231 ? -7.986 83.629 26.389 1.00 42.60 ? 264 ILE C CG2 1 ATOM 8478 C CD1 . ILE C 1 231 ? -5.143 83.233 27.426 1.00 51.36 ? 264 ILE C CD1 1 ATOM 8479 N N . THR C 1 232 ? -11.149 83.224 28.241 1.00 32.14 ? 265 THR C N 1 ATOM 8480 C CA . THR C 1 232 ? -12.224 82.442 27.589 1.00 34.73 ? 265 THR C CA 1 ATOM 8481 C C . THR C 1 232 ? -11.993 82.298 26.056 1.00 32.24 ? 265 THR C C 1 ATOM 8482 O O . THR C 1 232 ? -11.465 83.202 25.432 1.00 31.68 ? 265 THR C O 1 ATOM 8483 C CB . THR C 1 232 ? -13.600 83.077 27.802 1.00 35.07 ? 265 THR C CB 1 ATOM 8484 O OG1 . THR C 1 232 ? -13.700 84.293 27.031 1.00 31.96 ? 265 THR C OG1 1 ATOM 8485 C CG2 . THR C 1 232 ? -13.836 83.326 29.329 1.00 34.71 ? 265 THR C CG2 1 ATOM 8486 N N . ALA C 1 233 ? -12.355 81.158 25.476 1.00 30.05 ? 266 ALA C N 1 ATOM 8487 C CA . ALA C 1 233 ? -12.209 80.968 24.026 1.00 32.60 ? 266 ALA C CA 1 ATOM 8488 C C . ALA C 1 233 ? -13.108 81.988 23.262 1.00 32.24 ? 266 ALA C C 1 ATOM 8489 O O . ALA C 1 233 ? -12.680 82.692 22.271 1.00 30.30 ? 266 ALA C O 1 ATOM 8490 C CB . ALA C 1 233 ? -12.552 79.522 23.636 1.00 30.55 ? 266 ALA C CB 1 ATOM 8491 N N . MET C 1 234 ? -14.345 82.057 23.760 1.00 29.08 ? 267 MET C N 1 ATOM 8492 C CA . MET C 1 234 ? -15.334 83.000 23.289 1.00 29.54 ? 267 MET C CA 1 ATOM 8493 C C . MET C 1 234 ? -15.099 84.355 23.936 1.00 29.41 ? 267 MET C C 1 ATOM 8494 O O . MET C 1 234 ? -14.512 84.445 25.037 1.00 28.06 ? 267 MET C O 1 ATOM 8495 C CB . MET C 1 234 ? -16.760 82.556 23.661 1.00 30.32 ? 267 MET C CB 1 ATOM 8496 C CG . MET C 1 234 ? -17.400 81.608 22.709 1.00 31.89 ? 267 MET C CG 1 ATOM 8497 S SD . MET C 1 234 ? -18.640 80.652 23.570 1.00 36.19 ? 267 MET C SD 1 ATOM 8498 C CE . MET C 1 234 ? -19.696 81.945 24.078 1.00 36.88 ? 267 MET C CE 1 ATOM 8499 N N . ARG C 1 235 ? -15.606 85.393 23.274 1.00 28.81 ? 268 ARG C N 1 ATOM 8500 C CA . ARG C 1 235 ? -15.690 86.704 23.878 1.00 28.71 ? 268 ARG C CA 1 ATOM 8501 C C . ARG C 1 235 ? -16.589 86.563 25.090 1.00 29.25 ? 268 ARG C C 1 ATOM 8502 O O . ARG C 1 235 ? -17.682 85.949 25.015 1.00 26.46 ? 268 ARG C O 1 ATOM 8503 C CB . ARG C 1 235 ? -16.215 87.748 22.895 1.00 29.58 ? 268 ARG C CB 1 ATOM 8504 C CG . ARG C 1 235 ? -15.259 87.946 21.739 1.00 31.28 ? 268 ARG C CG 1 ATOM 8505 C CD . ARG C 1 235 ? -15.606 89.105 20.809 1.00 33.39 ? 268 ARG C CD 1 ATOM 8506 N NE . ARG C 1 235 ? -15.217 88.737 19.448 1.00 33.38 ? 268 ARG C NE 1 ATOM 8507 C CZ . ARG C 1 235 ? -16.004 88.779 18.383 1.00 32.04 ? 268 ARG C CZ 1 ATOM 8508 N NH1 . ARG C 1 235 ? -17.228 89.259 18.475 1.00 33.97 1 268 ARG C NH1 1 ATOM 8509 N NH2 . ARG C 1 235 ? -15.541 88.378 17.213 1.00 29.21 ? 268 ARG C NH2 1 ATOM 8510 N N . GLU C 1 236 ? -16.063 87.082 26.205 1.00 30.40 ? 269 GLU C N 1 ATOM 8511 C CA . GLU C 1 236 ? -16.705 87.095 27.517 1.00 33.03 ? 269 GLU C CA 1 ATOM 8512 C C . GLU C 1 236 ? -18.179 87.399 27.432 1.00 30.68 ? 269 GLU C C 1 ATOM 8513 O O . GLU C 1 236 ? -18.970 86.823 28.159 1.00 29.25 ? 269 GLU C O 1 ATOM 8514 C CB . GLU C 1 236 ? -15.984 88.140 28.386 1.00 40.68 ? 269 GLU C CB 1 ATOM 8515 C CG . GLU C 1 236 ? -16.747 88.737 29.576 1.00 47.85 ? 269 GLU C CG 1 ATOM 8516 C CD . GLU C 1 236 ? -15.826 89.434 30.592 1.00 54.12 ? 269 GLU C CD 1 ATOM 8517 O OE1 . GLU C 1 236 ? -14.590 89.239 30.505 1.00 62.61 ? 269 GLU C OE1 1 ATOM 8518 O OE2 . GLU C 1 236 ? -16.317 90.169 31.488 1.00 55.54 -1 269 GLU C OE2 1 ATOM 8519 N N . TYR C 1 237 ? -18.542 88.312 26.541 1.00 29.84 ? 270 TYR C N 1 ATOM 8520 C CA . TYR C 1 237 ? -19.940 88.707 26.370 1.00 31.24 ? 270 TYR C CA 1 ATOM 8521 C C . TYR C 1 237 ? -20.821 87.564 25.867 1.00 27.70 ? 270 TYR C C 1 ATOM 8522 O O . TYR C 1 237 ? -21.859 87.305 26.444 1.00 27.22 ? 270 TYR C O 1 ATOM 8523 C CB . TYR C 1 237 ? -20.059 89.957 25.480 1.00 34.37 ? 270 TYR C CB 1 ATOM 8524 C CG . TYR C 1 237 ? -21.470 90.287 25.087 1.00 39.97 ? 270 TYR C CG 1 ATOM 8525 C CD1 . TYR C 1 237 ? -22.368 90.899 25.987 1.00 44.51 ? 270 TYR C CD1 1 ATOM 8526 C CD2 . TYR C 1 237 ? -21.925 89.985 23.804 1.00 43.67 ? 270 TYR C CD2 1 ATOM 8527 C CE1 . TYR C 1 237 ? -23.679 91.185 25.604 1.00 45.06 ? 270 TYR C CE1 1 ATOM 8528 C CE2 . TYR C 1 237 ? -23.230 90.247 23.413 1.00 46.62 ? 270 TYR C CE2 1 ATOM 8529 C CZ . TYR C 1 237 ? -24.098 90.845 24.302 1.00 49.82 ? 270 TYR C CZ 1 ATOM 8530 O OH . TYR C 1 237 ? -25.365 91.088 23.835 1.00 56.91 ? 270 TYR C OH 1 ATOM 8531 N N . TYR C 1 238 ? -20.419 86.878 24.809 1.00 24.67 ? 271 TYR C N 1 ATOM 8532 C CA . TYR C 1 238 ? -21.227 85.788 24.321 1.00 24.29 ? 271 TYR C CA 1 ATOM 8533 C C . TYR C 1 238 ? -21.086 84.634 25.324 1.00 25.53 ? 271 TYR C C 1 ATOM 8534 O O . TYR C 1 238 ? -21.990 83.810 25.477 1.00 25.50 ? 271 TYR C O 1 ATOM 8535 C CB . TYR C 1 238 ? -20.784 85.301 22.956 1.00 24.96 ? 271 TYR C CB 1 ATOM 8536 C CG . TYR C 1 238 ? -20.679 86.335 21.886 1.00 27.29 ? 271 TYR C CG 1 ATOM 8537 C CD1 . TYR C 1 238 ? -21.844 86.950 21.354 1.00 28.32 ? 271 TYR C CD1 1 ATOM 8538 C CD2 . TYR C 1 238 ? -19.435 86.685 21.330 1.00 27.56 ? 271 TYR C CD2 1 ATOM 8539 C CE1 . TYR C 1 238 ? -21.779 87.865 20.302 1.00 26.27 ? 271 TYR C CE1 1 ATOM 8540 C CE2 . TYR C 1 238 ? -19.371 87.623 20.273 1.00 29.15 ? 271 TYR C CE2 1 ATOM 8541 C CZ . TYR C 1 238 ? -20.556 88.189 19.775 1.00 27.08 ? 271 TYR C CZ 1 ATOM 8542 O OH . TYR C 1 238 ? -20.549 89.111 18.808 1.00 28.42 ? 271 TYR C OH 1 ATOM 8543 N N . ASN C 1 239 ? -19.952 84.538 26.008 1.00 25.42 ? 272 ASN C N 1 ATOM 8544 C CA . ASN C 1 239 ? -19.803 83.482 27.010 1.00 25.86 ? 272 ASN C CA 1 ATOM 8545 C C . ASN C 1 239 ? -20.834 83.601 28.151 1.00 27.86 ? 272 ASN C C 1 ATOM 8546 O O . ASN C 1 239 ? -21.581 82.673 28.423 1.00 26.25 ? 272 ASN C O 1 ATOM 8547 C CB . ASN C 1 239 ? -18.391 83.497 27.546 1.00 25.74 ? 272 ASN C CB 1 ATOM 8548 C CG . ASN C 1 239 ? -18.160 82.370 28.464 1.00 26.49 ? 272 ASN C CG 1 ATOM 8549 O OD1 . ASN C 1 239 ? -18.395 81.197 28.106 1.00 28.24 ? 272 ASN C OD1 1 ATOM 8550 N ND2 . ASN C 1 239 ? -17.746 82.685 29.663 1.00 26.09 ? 272 ASN C ND2 1 ATOM 8551 N N . GLU C 1 240 ? -20.891 84.782 28.766 1.00 31.03 ? 273 GLU C N 1 ATOM 8552 C CA . GLU C 1 240 ? -21.961 85.172 29.699 1.00 32.88 ? 273 GLU C CA 1 ATOM 8553 C C . GLU C 1 240 ? -23.401 84.896 29.179 1.00 31.90 ? 273 GLU C C 1 ATOM 8554 O O . GLU C 1 240 ? -24.242 84.425 29.938 1.00 30.86 ? 273 GLU C O 1 ATOM 8555 C CB . GLU C 1 240 ? -21.833 86.664 30.084 1.00 34.60 ? 273 GLU C CB 1 ATOM 8556 C CG . GLU C 1 240 ? -20.558 87.089 30.839 1.00 37.77 ? 273 GLU C CG 1 ATOM 8557 C CD . GLU C 1 240 ? -20.231 86.225 32.073 1.00 40.70 ? 273 GLU C CD 1 ATOM 8558 O OE1 . GLU C 1 240 ? -21.182 85.825 32.798 1.00 44.13 ? 273 GLU C OE1 1 ATOM 8559 O OE2 . GLU C 1 240 ? -19.025 85.926 32.320 1.00 38.04 -1 273 GLU C OE2 1 ATOM 8560 N N . LYS C 1 241 ? -23.682 85.173 27.909 1.00 30.42 ? 274 LYS C N 1 ATOM 8561 C CA . LYS C 1 241 ? -25.053 85.041 27.399 1.00 33.06 ? 274 LYS C CA 1 ATOM 8562 C C . LYS C 1 241 ? -25.425 83.563 27.230 1.00 29.00 ? 274 LYS C C 1 ATOM 8563 O O . LYS C 1 241 ? -26.543 83.133 27.545 1.00 25.56 ? 274 LYS C O 1 ATOM 8564 C CB . LYS C 1 241 ? -25.246 85.848 26.095 1.00 37.84 ? 274 LYS C CB 1 ATOM 8565 C CG . LYS C 1 241 ? -26.634 85.737 25.443 1.00 44.63 ? 274 LYS C CG 1 ATOM 8566 C CD . LYS C 1 241 ? -27.659 86.721 26.038 1.00 53.23 ? 274 LYS C CD 1 ATOM 8567 C CE . LYS C 1 241 ? -29.009 86.747 25.282 1.00 54.40 ? 274 LYS C CE 1 ATOM 8568 N NZ . LYS C 1 241 ? -30.190 87.044 26.151 1.00 51.21 1 274 LYS C NZ 1 ATOM 8569 N N . LEU C 1 242 ? -24.470 82.764 26.770 1.00 28.58 ? 275 LEU C N 1 ATOM 8570 C CA . LEU C 1 242 ? -24.696 81.306 26.640 1.00 26.88 ? 275 LEU C CA 1 ATOM 8571 C C . LEU C 1 242 ? -24.953 80.656 28.022 1.00 25.10 ? 275 LEU C C 1 ATOM 8572 O O . LEU C 1 242 ? -25.893 79.869 28.202 1.00 20.61 ? 275 LEU C O 1 ATOM 8573 C CB . LEU C 1 242 ? -23.542 80.646 25.889 1.00 24.86 ? 275 LEU C CB 1 ATOM 8574 C CG . LEU C 1 242 ? -23.596 80.758 24.386 1.00 26.40 ? 275 LEU C CG 1 ATOM 8575 C CD1 . LEU C 1 242 ? -22.401 80.007 23.794 1.00 26.31 ? 275 LEU C CD1 1 ATOM 8576 C CD2 . LEU C 1 242 ? -24.930 80.210 23.822 1.00 26.11 ? 275 LEU C CD2 1 ATOM 8577 N N . ILE C 1 243 ? -24.136 81.059 28.988 1.00 25.54 ? 276 ILE C N 1 ATOM 8578 C CA . ILE C 1 243 ? -24.207 80.525 30.336 1.00 28.77 ? 276 ILE C CA 1 ATOM 8579 C C . ILE C 1 243 ? -25.644 80.715 30.811 1.00 30.36 ? 276 ILE C C 1 ATOM 8580 O O . ILE C 1 243 ? -26.286 79.754 31.239 1.00 32.22 ? 276 ILE C O 1 ATOM 8581 C CB . ILE C 1 243 ? -23.153 81.207 31.325 1.00 28.47 ? 276 ILE C CB 1 ATOM 8582 C CG1 . ILE C 1 243 ? -21.689 80.840 31.024 1.00 29.75 ? 276 ILE C CG1 1 ATOM 8583 C CG2 . ILE C 1 243 ? -23.355 80.778 32.759 1.00 28.34 ? 276 ILE C CG2 1 ATOM 8584 C CD1 . ILE C 1 243 ? -21.465 79.444 30.463 1.00 29.58 ? 276 ILE C CD1 1 ATOM 8585 N N . ASP C 1 244 ? -26.130 81.951 30.724 1.00 32.71 ? 277 ASP C N 1 ATOM 8586 C CA . ASP C 1 244 ? -27.438 82.317 31.258 1.00 35.05 ? 277 ASP C CA 1 ATOM 8587 C C . ASP C 1 244 ? -28.512 81.566 30.507 1.00 30.36 ? 277 ASP C C 1 ATOM 8588 O O . ASP C 1 244 ? -29.398 81.047 31.164 1.00 28.60 ? 277 ASP C O 1 ATOM 8589 C CB . ASP C 1 244 ? -27.674 83.851 31.262 1.00 40.35 ? 277 ASP C CB 1 ATOM 8590 C CG . ASP C 1 244 ? -26.693 84.608 32.234 1.00 51.03 ? 277 ASP C CG 1 ATOM 8591 O OD1 . ASP C 1 244 ? -26.386 84.115 33.383 1.00 53.76 ? 277 ASP C OD1 1 ATOM 8592 O OD2 . ASP C 1 244 ? -26.209 85.706 31.834 1.00 58.69 -1 277 ASP C OD2 1 ATOM 8593 N N . ILE C 1 245 ? -28.403 81.431 29.170 1.00 29.52 ? 278 ILE C N 1 ATOM 8594 C CA . ILE C 1 245 ? -29.312 80.502 28.428 1.00 27.36 ? 278 ILE C CA 1 ATOM 8595 C C . ILE C 1 245 ? -29.263 79.067 28.954 1.00 26.41 ? 278 ILE C C 1 ATOM 8596 O O . ILE C 1 245 ? -30.309 78.490 29.279 1.00 28.13 ? 278 ILE C O 1 ATOM 8597 C CB . ILE C 1 245 ? -29.067 80.386 26.914 1.00 26.15 ? 278 ILE C CB 1 ATOM 8598 C CG1 . ILE C 1 245 ? -29.410 81.707 26.194 1.00 24.75 ? 278 ILE C CG1 1 ATOM 8599 C CG2 . ILE C 1 245 ? -29.893 79.203 26.327 1.00 24.29 ? 278 ILE C CG2 1 ATOM 8600 C CD1 . ILE C 1 245 ? -28.896 81.778 24.740 1.00 23.72 ? 278 ILE C CD1 1 ATOM 8601 N N . PHE C 1 246 ? -28.061 78.506 29.030 1.00 25.37 ? 279 PHE C N 1 ATOM 8602 C CA . PHE C 1 246 ? -27.858 77.120 29.546 1.00 25.37 ? 279 PHE C CA 1 ATOM 8603 C C . PHE C 1 246 ? -28.398 76.886 30.973 1.00 24.54 ? 279 PHE C C 1 ATOM 8604 O O . PHE C 1 246 ? -28.998 75.860 31.274 1.00 23.42 ? 279 PHE C O 1 ATOM 8605 C CB . PHE C 1 246 ? -26.357 76.715 29.474 1.00 25.06 ? 279 PHE C CB 1 ATOM 8606 C CG . PHE C 1 246 ? -25.790 76.571 28.047 1.00 23.21 ? 279 PHE C CG 1 ATOM 8607 C CD1 . PHE C 1 246 ? -26.607 76.249 26.957 1.00 22.25 ? 279 PHE C CD1 1 ATOM 8608 C CD2 . PHE C 1 246 ? -24.410 76.723 27.825 1.00 21.09 ? 279 PHE C CD2 1 ATOM 8609 C CE1 . PHE C 1 246 ? -26.068 76.097 25.693 1.00 21.29 ? 279 PHE C CE1 1 ATOM 8610 C CE2 . PHE C 1 246 ? -23.879 76.556 26.588 1.00 20.35 ? 279 PHE C CE2 1 ATOM 8611 C CZ . PHE C 1 246 ? -24.704 76.250 25.515 1.00 21.12 ? 279 PHE C CZ 1 ATOM 8612 N N . GLN C 1 247 ? -28.163 77.849 31.841 1.00 27.47 ? 280 GLN C N 1 ATOM 8613 C CA . GLN C 1 247 ? -28.717 77.842 33.190 1.00 29.70 ? 280 GLN C CA 1 ATOM 8614 C C . GLN C 1 247 ? -30.236 77.797 33.202 1.00 31.32 ? 280 GLN C C 1 ATOM 8615 O O . GLN C 1 247 ? -30.805 76.962 33.893 1.00 31.19 ? 280 GLN C O 1 ATOM 8616 C CB . GLN C 1 247 ? -28.287 79.100 33.903 1.00 29.67 ? 280 GLN C CB 1 ATOM 8617 C CG . GLN C 1 247 ? -26.801 79.140 34.156 1.00 30.47 ? 280 GLN C CG 1 ATOM 8618 C CD . GLN C 1 247 ? -26.422 80.352 34.972 1.00 29.43 ? 280 GLN C CD 1 ATOM 8619 O OE1 . GLN C 1 247 ? -26.793 81.504 34.664 1.00 27.98 ? 280 GLN C OE1 1 ATOM 8620 N NE2 . GLN C 1 247 ? -25.679 80.100 36.014 1.00 27.93 ? 280 GLN C NE2 1 ATOM 8621 N N . LYS C 1 248 ? -30.870 78.699 32.439 1.00 32.73 ? 281 LYS C N 1 ATOM 8622 C CA . LYS C 1 248 ? -32.328 78.695 32.212 1.00 34.76 ? 281 LYS C CA 1 ATOM 8623 C C . LYS C 1 248 ? -32.944 77.353 31.750 1.00 30.90 ? 281 LYS C C 1 ATOM 8624 O O . LYS C 1 248 ? -34.082 77.069 32.057 1.00 27.67 ? 281 LYS C O 1 ATOM 8625 C CB . LYS C 1 248 ? -32.695 79.743 31.158 1.00 42.67 ? 281 LYS C CB 1 ATOM 8626 C CG . LYS C 1 248 ? -33.343 81.013 31.678 1.00 50.07 ? 281 LYS C CG 1 ATOM 8627 C CD . LYS C 1 248 ? -34.115 81.762 30.566 1.00 59.77 ? 281 LYS C CD 1 ATOM 8628 C CE . LYS C 1 248 ? -33.263 82.790 29.785 1.00 62.72 ? 281 LYS C CE 1 ATOM 8629 N NZ . LYS C 1 248 ? -32.953 84.037 30.552 1.00 61.92 1 281 LYS C NZ 1 ATOM 8630 N N . TYR C 1 249 ? -32.209 76.559 30.978 1.00 28.82 ? 282 TYR C N 1 ATOM 8631 C CA . TYR C 1 249 ? -32.749 75.352 30.389 1.00 28.32 ? 282 TYR C CA 1 ATOM 8632 C C . TYR C 1 249 ? -31.983 74.104 30.813 1.00 27.26 ? 282 TYR C C 1 ATOM 8633 O O . TYR C 1 249 ? -31.958 73.039 30.085 1.00 25.12 ? 282 TYR C O 1 ATOM 8634 C CB . TYR C 1 249 ? -32.802 75.517 28.870 1.00 28.99 ? 282 TYR C CB 1 ATOM 8635 C CG . TYR C 1 249 ? -33.808 76.559 28.468 1.00 30.97 ? 282 TYR C CG 1 ATOM 8636 C CD1 . TYR C 1 249 ? -35.152 76.245 28.346 1.00 31.62 ? 282 TYR C CD1 1 ATOM 8637 C CD2 . TYR C 1 249 ? -33.418 77.886 28.248 1.00 32.94 ? 282 TYR C CD2 1 ATOM 8638 C CE1 . TYR C 1 249 ? -36.083 77.212 27.996 1.00 32.27 ? 282 TYR C CE1 1 ATOM 8639 C CE2 . TYR C 1 249 ? -34.333 78.860 27.895 1.00 31.27 ? 282 TYR C CE2 1 ATOM 8640 C CZ . TYR C 1 249 ? -35.669 78.519 27.767 1.00 32.68 ? 282 TYR C CZ 1 ATOM 8641 O OH . TYR C 1 249 ? -36.583 79.488 27.398 1.00 31.24 ? 282 TYR C OH 1 ATOM 8642 N N . SER C 1 250 ? -31.385 74.207 32.001 1.00 26.04 ? 283 SER C N 1 ATOM 8643 C CA . SER C 1 250 ? -30.586 73.095 32.552 1.00 28.10 ? 283 SER C CA 1 ATOM 8644 C C . SER C 1 250 ? -31.360 71.781 32.676 1.00 27.55 ? 283 SER C C 1 ATOM 8645 O O . SER C 1 250 ? -30.784 70.730 32.471 1.00 29.43 ? 283 SER C O 1 ATOM 8646 C CB . SER C 1 250 ? -29.964 73.459 33.906 1.00 30.30 ? 283 SER C CB 1 ATOM 8647 O OG . SER C 1 250 ? -30.903 73.559 34.979 1.00 27.86 ? 283 SER C OG 1 ATOM 8648 N N . ASP C 1 251 ? -32.653 71.853 32.996 1.00 29.20 ? 284 ASP C N 1 ATOM 8649 C CA . ASP C 1 251 ? -33.560 70.679 32.936 1.00 30.75 ? 284 ASP C CA 1 ATOM 8650 C C . ASP C 1 251 ? -33.551 69.928 31.604 1.00 26.91 ? 284 ASP C C 1 ATOM 8651 O O . ASP C 1 251 ? -33.323 68.728 31.590 1.00 27.13 ? 284 ASP C O 1 ATOM 8652 C CB . ASP C 1 251 ? -35.010 71.007 33.358 1.00 37.42 ? 284 ASP C CB 1 ATOM 8653 C CG . ASP C 1 251 ? -35.588 72.312 32.727 1.00 46.62 ? 284 ASP C CG 1 ATOM 8654 O OD1 . ASP C 1 251 ? -36.614 72.756 33.295 1.00 58.64 ? 284 ASP C OD1 1 ATOM 8655 O OD2 . ASP C 1 251 ? -35.078 72.899 31.718 1.00 45.92 -1 284 ASP C OD2 1 ATOM 8656 N N . VAL C 1 252 ? -33.759 70.639 30.498 1.00 25.45 ? 285 VAL C N 1 ATOM 8657 C CA . VAL C 1 252 ? -33.854 70.035 29.134 1.00 25.67 ? 285 VAL C CA 1 ATOM 8658 C C . VAL C 1 252 ? -32.516 69.403 28.671 1.00 22.98 ? 285 VAL C C 1 ATOM 8659 O O . VAL C 1 252 ? -32.536 68.325 28.084 1.00 19.84 ? 285 VAL C O 1 ATOM 8660 C CB . VAL C 1 252 ? -34.215 71.090 28.021 1.00 27.88 ? 285 VAL C CB 1 ATOM 8661 C CG1 . VAL C 1 252 ? -35.102 70.496 26.978 1.00 28.40 ? 285 VAL C CG1 1 ATOM 8662 C CG2 . VAL C 1 252 ? -34.901 72.320 28.569 1.00 31.70 ? 285 VAL C CG2 1 ATOM 8663 N N . ILE C 1 253 ? -31.397 70.136 28.901 1.00 20.07 ? 286 ILE C N 1 ATOM 8664 C CA . ILE C 1 253 ? -30.077 69.794 28.407 1.00 19.09 ? 286 ILE C CA 1 ATOM 8665 C C . ILE C 1 253 ? -29.563 68.711 29.345 1.00 19.19 ? 286 ILE C C 1 ATOM 8666 O O . ILE C 1 253 ? -29.459 68.910 30.556 1.00 19.05 ? 286 ILE C O 1 ATOM 8667 C CB . ILE C 1 253 ? -29.131 71.045 28.400 1.00 19.99 ? 286 ILE C CB 1 ATOM 8668 C CG1 . ILE C 1 253 ? -29.640 72.111 27.360 1.00 21.00 ? 286 ILE C CG1 1 ATOM 8669 C CG2 . ILE C 1 253 ? -27.654 70.699 28.148 1.00 18.33 ? 286 ILE C CG2 1 ATOM 8670 C CD1 . ILE C 1 253 ? -29.285 73.561 27.657 1.00 18.57 ? 286 ILE C CD1 1 ATOM 8671 N N . ALA C 1 254 ? -29.305 67.553 28.772 1.00 18.88 ? 287 ALA C N 1 ATOM 8672 C CA . ALA C 1 254 ? -28.756 66.428 29.455 1.00 19.65 ? 287 ALA C CA 1 ATOM 8673 C C . ALA C 1 254 ? -27.225 66.270 29.194 1.00 22.23 ? 287 ALA C C 1 ATOM 8674 O O . ALA C 1 254 ? -26.603 65.300 29.608 1.00 26.06 ? 287 ALA C O 1 ATOM 8675 C CB . ALA C 1 254 ? -29.503 65.204 28.996 1.00 20.07 ? 287 ALA C CB 1 ATOM 8676 N N . GLY C 1 255 ? -26.604 67.230 28.521 1.00 22.42 ? 288 GLY C N 1 ATOM 8677 C CA . GLY C 1 255 ? -25.171 67.196 28.276 1.00 21.02 ? 288 GLY C CA 1 ATOM 8678 C C . GLY C 1 255 ? -24.792 68.050 27.039 1.00 19.90 ? 288 GLY C C 1 ATOM 8679 O O . GLY C 1 255 ? -25.576 68.192 26.046 1.00 15.91 ? 288 GLY C O 1 ATOM 8680 N N . GLN C 1 256 ? -23.555 68.545 27.132 1.00 16.84 ? 289 GLN C N 1 ATOM 8681 C CA . GLN C 1 256 ? -23.007 69.513 26.281 1.00 15.24 ? 289 GLN C CA 1 ATOM 8682 C C . GLN C 1 256 ? -21.683 68.872 25.764 1.00 14.55 ? 289 GLN C C 1 ATOM 8683 O O . GLN C 1 256 ? -21.015 68.206 26.520 1.00 14.94 ? 289 GLN C O 1 ATOM 8684 C CB . GLN C 1 256 ? -22.795 70.747 27.116 1.00 15.11 ? 289 GLN C CB 1 ATOM 8685 C CG . GLN C 1 256 ? -24.008 71.653 27.216 1.00 16.88 ? 289 GLN C CG 1 ATOM 8686 C CD . GLN C 1 256 ? -23.666 72.969 27.972 1.00 19.29 ? 289 GLN C CD 1 ATOM 8687 O OE1 . GLN C 1 256 ? -22.675 73.713 27.625 1.00 19.71 ? 289 GLN C OE1 1 ATOM 8688 N NE2 . GLN C 1 256 ? -24.401 73.207 29.088 1.00 17.87 ? 289 GLN C NE2 1 ATOM 8689 N N . PHE C 1 257 ? -21.334 68.996 24.491 1.00 14.07 ? 290 PHE C N 1 ATOM 8690 C CA . PHE C 1 257 ? -20.115 68.334 23.976 1.00 15.37 ? 290 PHE C CA 1 ATOM 8691 C C . PHE C 1 257 ? -19.318 69.240 23.100 1.00 14.04 ? 290 PHE C C 1 ATOM 8692 O O . PHE C 1 257 ? -19.868 69.974 22.343 1.00 12.73 ? 290 PHE C O 1 ATOM 8693 C CB . PHE C 1 257 ? -20.435 66.978 23.250 1.00 17.00 ? 290 PHE C CB 1 ATOM 8694 C CG . PHE C 1 257 ? -21.262 66.074 24.078 1.00 18.79 ? 290 PHE C CG 1 ATOM 8695 C CD1 . PHE C 1 257 ? -20.685 65.054 24.802 1.00 19.01 ? 290 PHE C CD1 1 ATOM 8696 C CD2 . PHE C 1 257 ? -22.649 66.331 24.218 1.00 19.32 ? 290 PHE C CD2 1 ATOM 8697 C CE1 . PHE C 1 257 ? -21.498 64.268 25.639 1.00 21.81 ? 290 PHE C CE1 1 ATOM 8698 C CE2 . PHE C 1 257 ? -23.441 65.552 25.032 1.00 20.34 ? 290 PHE C CE2 1 ATOM 8699 C CZ . PHE C 1 257 ? -22.867 64.525 25.763 1.00 21.91 ? 290 PHE C CZ 1 ATOM 8700 N N . TYR C 1 258 ? -18.013 69.200 23.228 1.00 14.90 ? 291 TYR C N 1 ATOM 8701 C CA . TYR C 1 258 ? -17.174 70.220 22.549 1.00 16.82 ? 291 TYR C CA 1 ATOM 8702 C C . TYR C 1 258 ? -15.783 69.711 22.062 1.00 17.13 ? 291 TYR C C 1 ATOM 8703 O O . TYR C 1 258 ? -15.344 68.594 22.393 1.00 18.49 ? 291 TYR C O 1 ATOM 8704 C CB . TYR C 1 258 ? -16.958 71.442 23.460 1.00 18.74 ? 291 TYR C CB 1 ATOM 8705 C CG . TYR C 1 258 ? -18.206 72.196 23.962 1.00 20.29 ? 291 TYR C CG 1 ATOM 8706 C CD1 . TYR C 1 258 ? -18.957 73.014 23.103 1.00 20.41 ? 291 TYR C CD1 1 ATOM 8707 C CD2 . TYR C 1 258 ? -18.610 72.113 25.309 1.00 23.76 ? 291 TYR C CD2 1 ATOM 8708 C CE1 . TYR C 1 258 ? -20.077 73.708 23.534 1.00 21.60 ? 291 TYR C CE1 1 ATOM 8709 C CE2 . TYR C 1 258 ? -19.770 72.803 25.751 1.00 25.46 ? 291 TYR C CE2 1 ATOM 8710 C CZ . TYR C 1 258 ? -20.497 73.611 24.858 1.00 23.78 ? 291 TYR C CZ 1 ATOM 8711 O OH . TYR C 1 258 ? -21.608 74.344 25.301 1.00 24.27 ? 291 TYR C OH 1 ATOM 8712 N N . GLY C 1 259 ? -15.116 70.521 21.244 1.00 17.00 ? 292 GLY C N 1 ATOM 8713 C CA . GLY C 1 259 ? -13.815 70.212 20.710 1.00 16.91 ? 292 GLY C CA 1 ATOM 8714 C C . GLY C 1 259 ? -12.863 71.354 20.961 1.00 18.52 ? 292 GLY C C 1 ATOM 8715 O O . GLY C 1 259 ? -12.752 71.874 22.093 1.00 18.29 ? 292 GLY C O 1 ATOM 8716 N N . HIS C 1 260 ? -12.162 71.723 19.876 1.00 20.34 ? 293 HIS C N 1 ATOM 8717 C CA . HIS C 1 260 ? -11.330 72.944 19.683 1.00 18.06 ? 293 HIS C CA 1 ATOM 8718 C C . HIS C 1 260 ? -10.000 72.950 20.423 1.00 17.13 ? 293 HIS C C 1 ATOM 8719 O O . HIS C 1 260 ? -8.979 73.166 19.775 1.00 19.79 ? 293 HIS C O 1 ATOM 8720 C CB . HIS C 1 260 ? -12.120 74.219 19.900 1.00 17.94 ? 293 HIS C CB 1 ATOM 8721 C CG . HIS C 1 260 ? -11.308 75.466 19.728 1.00 18.20 ? 293 HIS C CG 1 ATOM 8722 N ND1 . HIS C 1 260 ? -10.748 75.838 18.521 1.00 18.27 ? 293 HIS C ND1 1 ATOM 8723 C CD2 . HIS C 1 260 ? -10.980 76.445 20.609 1.00 18.41 ? 293 HIS C CD2 1 ATOM 8724 C CE1 . HIS C 1 260 ? -10.082 76.976 18.668 1.00 18.76 ? 293 HIS C CE1 1 ATOM 8725 N NE2 . HIS C 1 260 ? -10.210 77.369 19.926 1.00 19.03 ? 293 HIS C NE2 1 ATOM 8726 N N . THR C 1 261 ? -9.990 72.722 21.733 1.00 15.45 ? 294 THR C N 1 ATOM 8727 C CA . THR C 1 261 ? -8.703 72.673 22.556 1.00 15.22 ? 294 THR C CA 1 ATOM 8728 C C . THR C 1 261 ? -7.694 71.484 22.314 1.00 14.66 ? 294 THR C C 1 ATOM 8729 O O . THR C 1 261 ? -6.497 71.573 22.621 1.00 13.00 ? 294 THR C O 1 ATOM 8730 C CB . THR C 1 261 ? -9.035 72.652 24.067 1.00 14.65 ? 294 THR C CB 1 ATOM 8731 O OG1 . THR C 1 261 ? -9.710 71.392 24.420 1.00 14.65 ? 294 THR C OG1 1 ATOM 8732 C CG2 . THR C 1 261 ? -9.886 73.828 24.393 1.00 14.06 ? 294 THR C CG2 1 ATOM 8733 N N . HIS C 1 262 ? -8.222 70.367 21.800 1.00 14.80 ? 295 HIS C N 1 ATOM 8734 C CA . HIS C 1 262 ? -7.475 69.140 21.647 1.00 14.82 ? 295 HIS C CA 1 ATOM 8735 C C . HIS C 1 262 ? -7.070 68.513 22.982 1.00 14.13 ? 295 HIS C C 1 ATOM 8736 O O . HIS C 1 262 ? -6.185 67.670 23.047 1.00 14.81 ? 295 HIS C O 1 ATOM 8737 C CB . HIS C 1 262 ? -6.235 69.362 20.760 1.00 15.52 ? 295 HIS C CB 1 ATOM 8738 C CG . HIS C 1 262 ? -6.521 69.926 19.431 1.00 14.02 ? 295 HIS C CG 1 ATOM 8739 N ND1 . HIS C 1 262 ? -5.528 70.117 18.510 1.00 14.67 ? 295 HIS C ND1 1 ATOM 8740 C CD2 . HIS C 1 262 ? -7.667 70.317 18.844 1.00 14.84 ? 295 HIS C CD2 1 ATOM 8741 C CE1 . HIS C 1 262 ? -6.042 70.628 17.402 1.00 15.02 ? 295 HIS C CE1 1 ATOM 8742 N NE2 . HIS C 1 262 ? -7.342 70.752 17.575 1.00 15.84 ? 295 HIS C NE2 1 ATOM 8743 N N . ARG C 1 263 ? -7.817 68.871 23.998 1.00 15.94 ? 296 ARG C N 1 ATOM 8744 C CA . ARG C 1 263 ? -7.655 68.406 25.400 1.00 17.62 ? 296 ARG C CA 1 ATOM 8745 C C . ARG C 1 263 ? -8.934 67.767 25.997 1.00 16.63 ? 296 ARG C C 1 ATOM 8746 O O . ARG C 1 263 ? -10.078 68.078 25.602 1.00 16.04 ? 296 ARG C O 1 ATOM 8747 C CB . ARG C 1 263 ? -7.209 69.587 26.321 1.00 19.34 ? 296 ARG C CB 1 ATOM 8748 C CG . ARG C 1 263 ? -5.908 70.284 25.914 1.00 19.34 ? 296 ARG C CG 1 ATOM 8749 C CD . ARG C 1 263 ? -4.789 69.230 25.937 1.00 20.01 ? 296 ARG C CD 1 ATOM 8750 N NE . ARG C 1 263 ? -3.530 69.789 25.450 1.00 21.66 ? 296 ARG C NE 1 ATOM 8751 C CZ . ARG C 1 263 ? -3.109 69.771 24.166 1.00 21.06 ? 296 ARG C CZ 1 ATOM 8752 N NH1 . ARG C 1 263 ? -3.820 69.194 23.147 1.00 17.49 1 296 ARG C NH1 1 ATOM 8753 N NH2 . ARG C 1 263 ? -1.921 70.349 23.921 1.00 20.93 ? 296 ARG C NH2 1 ATOM 8754 N N . ASP C 1 264 ? -8.684 66.910 26.982 1.00 15.60 ? 297 ASP C N 1 ATOM 8755 C CA . ASP C 1 264 ? -9.679 66.118 27.629 1.00 15.24 ? 297 ASP C CA 1 ATOM 8756 C C . ASP C 1 264 ? -9.932 66.902 28.862 1.00 16.99 ? 297 ASP C C 1 ATOM 8757 O O . ASP C 1 264 ? -9.082 66.924 29.738 1.00 17.71 ? 297 ASP C O 1 ATOM 8758 C CB . ASP C 1 264 ? -9.101 64.735 28.003 1.00 14.78 ? 297 ASP C CB 1 ATOM 8759 C CG . ASP C 1 264 ? -10.179 63.706 28.432 1.00 13.34 ? 297 ASP C CG 1 ATOM 8760 O OD1 . ASP C 1 264 ? -11.280 64.183 28.842 1.00 12.80 ? 297 ASP C OD1 1 ATOM 8761 O OD2 . ASP C 1 264 ? -9.910 62.459 28.418 1.00 11.16 -1 297 ASP C OD2 1 ATOM 8762 N N . SER C 1 265 ? -11.103 67.562 28.896 1.00 18.59 ? 298 SER C N 1 ATOM 8763 C CA . SER C 1 265 ? -11.635 68.347 30.046 1.00 17.74 ? 298 SER C CA 1 ATOM 8764 C C . SER C 1 265 ? -13.136 68.072 30.293 1.00 18.23 ? 298 SER C C 1 ATOM 8765 O O . SER C 1 265 ? -13.917 67.649 29.364 1.00 15.36 ? 298 SER C O 1 ATOM 8766 C CB . SER C 1 265 ? -11.562 69.854 29.761 1.00 17.05 ? 298 SER C CB 1 ATOM 8767 O OG . SER C 1 265 ? -10.259 70.280 29.727 1.00 18.22 ? 298 SER C OG 1 ATOM 8768 N N . ILE C 1 266 ? -13.512 68.396 31.533 1.00 18.71 ? 299 ILE C N 1 ATOM 8769 C CA . ILE C 1 266 ? -14.900 68.526 31.945 1.00 20.40 ? 299 ILE C CA 1 ATOM 8770 C C . ILE C 1 266 ? -15.153 69.890 32.506 1.00 19.96 ? 299 ILE C C 1 ATOM 8771 O O . ILE C 1 266 ? -14.263 70.487 33.034 1.00 19.21 ? 299 ILE C O 1 ATOM 8772 C CB . ILE C 1 266 ? -15.320 67.526 33.032 1.00 21.19 ? 299 ILE C CB 1 ATOM 8773 C CG1 . ILE C 1 266 ? -14.502 67.725 34.303 1.00 20.14 ? 299 ILE C CG1 1 ATOM 8774 C CG2 . ILE C 1 266 ? -15.239 66.113 32.467 1.00 22.81 ? 299 ILE C CG2 1 ATOM 8775 C CD1 . ILE C 1 266 ? -14.323 66.419 35.058 1.00 20.87 ? 299 ILE C CD1 1 ATOM 8776 N N . MET C 1 267 ? -16.388 70.375 32.369 1.00 20.47 ? 300 MET C N 1 ATOM 8777 C CA . MET C 1 267 ? -16.855 71.531 33.155 1.00 20.31 ? 300 MET C CA 1 ATOM 8778 C C . MET C 1 267 ? -18.193 71.167 33.800 1.00 19.50 ? 300 MET C C 1 ATOM 8779 O O . MET C 1 267 ? -18.917 70.271 33.321 1.00 17.19 ? 300 MET C O 1 ATOM 8780 C CB . MET C 1 267 ? -16.937 72.848 32.319 1.00 19.65 ? 300 MET C CB 1 ATOM 8781 C CG . MET C 1 267 ? -15.582 73.452 31.942 1.00 19.49 ? 300 MET C CG 1 ATOM 8782 S SD . MET C 1 267 ? -15.600 74.729 30.646 1.00 19.50 ? 300 MET C SD 1 ATOM 8783 C CE . MET C 1 267 ? -15.913 73.653 29.254 1.00 16.93 ? 300 MET C CE 1 ATOM 8784 N N . VAL C 1 268 ? -18.473 71.842 34.915 1.00 20.27 ? 301 VAL C N 1 ATOM 8785 C CA . VAL C 1 268 ? -19.754 71.763 35.570 1.00 21.79 ? 301 VAL C CA 1 ATOM 8786 C C . VAL C 1 268 ? -20.312 73.149 35.637 1.00 22.72 ? 301 VAL C C 1 ATOM 8787 O O . VAL C 1 268 ? -19.724 74.030 36.257 1.00 26.86 ? 301 VAL C O 1 ATOM 8788 C CB . VAL C 1 268 ? -19.640 71.235 36.981 1.00 22.79 ? 301 VAL C CB 1 ATOM 8789 C CG1 . VAL C 1 268 ? -20.983 71.272 37.648 1.00 24.11 ? 301 VAL C CG1 1 ATOM 8790 C CG2 . VAL C 1 268 ? -19.162 69.797 36.959 1.00 24.56 ? 301 VAL C CG2 1 ATOM 8791 N N . LEU C 1 269 ? -21.458 73.326 35.000 1.00 23.31 ? 302 LEU C N 1 ATOM 8792 C CA . LEU C 1 269 ? -22.174 74.582 34.972 1.00 24.37 ? 302 LEU C CA 1 ATOM 8793 C C . LEU C 1 269 ? -23.071 74.587 36.177 1.00 25.13 ? 302 LEU C C 1 ATOM 8794 O O . LEU C 1 269 ? -23.693 73.596 36.503 1.00 28.13 ? 302 LEU C O 1 ATOM 8795 C CB . LEU C 1 269 ? -22.977 74.706 33.653 1.00 24.50 ? 302 LEU C CB 1 ATOM 8796 C CG . LEU C 1 269 ? -23.887 75.918 33.477 1.00 24.84 ? 302 LEU C CG 1 ATOM 8797 C CD1 . LEU C 1 269 ? -23.055 77.189 33.566 1.00 24.45 ? 302 LEU C CD1 1 ATOM 8798 C CD2 . LEU C 1 269 ? -24.713 75.917 32.189 1.00 25.23 ? 302 LEU C CD2 1 ATOM 8799 N N . SER C 1 270 ? -23.097 75.694 36.877 1.00 28.10 ? 303 SER C N 1 ATOM 8800 C CA . SER C 1 270 ? -23.983 75.829 37.996 1.00 29.69 ? 303 SER C CA 1 ATOM 8801 C C . SER C 1 270 ? -25.037 76.866 37.717 1.00 32.53 ? 303 SER C C 1 ATOM 8802 O O . SER C 1 270 ? -24.899 77.759 36.840 1.00 27.10 ? 303 SER C O 1 ATOM 8803 C CB . SER C 1 270 ? -23.236 76.164 39.278 1.00 30.09 ? 303 SER C CB 1 ATOM 8804 O OG . SER C 1 270 ? -22.562 75.016 39.761 1.00 32.45 ? 303 SER C OG 1 ATOM 8805 N N . ASP C 1 271 ? -26.119 76.704 38.478 1.00 35.70 ? 304 ASP C N 1 ATOM 8806 C CA . ASP C 1 271 ? -27.237 77.604 38.402 1.00 37.22 ? 304 ASP C CA 1 ATOM 8807 C C . ASP C 1 271 ? -26.843 78.862 39.136 1.00 41.38 ? 304 ASP C C 1 ATOM 8808 O O . ASP C 1 271 ? -25.857 78.854 39.904 1.00 38.60 ? 304 ASP C O 1 ATOM 8809 C CB . ASP C 1 271 ? -28.521 76.942 38.942 1.00 37.82 ? 304 ASP C CB 1 ATOM 8810 C CG . ASP C 1 271 ? -28.529 76.709 40.458 1.00 35.68 ? 304 ASP C CG 1 ATOM 8811 O OD1 . ASP C 1 271 ? -27.595 77.062 41.217 1.00 32.37 ? 304 ASP C OD1 1 ATOM 8812 O OD2 . ASP C 1 271 ? -29.534 76.122 40.878 1.00 36.70 -1 304 ASP C OD2 1 ATOM 8813 N N . LYS C 1 272 ? -27.593 79.942 38.907 1.00 48.38 ? 305 LYS C N 1 ATOM 8814 C CA . LYS C 1 272 ? -27.254 81.225 39.531 1.00 54.65 ? 305 LYS C CA 1 ATOM 8815 C C . LYS C 1 272 ? -27.175 81.163 41.084 1.00 51.31 ? 305 LYS C C 1 ATOM 8816 O O . LYS C 1 272 ? -26.517 81.971 41.697 1.00 48.94 ? 305 LYS C O 1 ATOM 8817 C CB . LYS C 1 272 ? -28.138 82.365 38.988 1.00 59.01 ? 305 LYS C CB 1 ATOM 8818 C CG . LYS C 1 272 ? -27.546 83.083 37.749 1.00 66.52 ? 305 LYS C CG 1 ATOM 8819 C CD . LYS C 1 272 ? -26.348 84.035 38.054 1.00 73.38 ? 305 LYS C CD 1 ATOM 8820 C CE . LYS C 1 272 ? -24.936 83.510 37.689 1.00 75.85 ? 305 LYS C CE 1 ATOM 8821 N NZ . LYS C 1 272 ? -24.648 83.438 36.209 1.00 78.53 1 305 LYS C NZ 1 ATOM 8822 N N . LYS C 1 273 ? -27.758 80.145 41.698 1.00 54.48 ? 306 LYS C N 1 ATOM 8823 C CA . LYS C 1 273 ? -27.624 79.942 43.140 1.00 57.27 ? 306 LYS C CA 1 ATOM 8824 C C . LYS C 1 273 ? -26.382 79.125 43.579 1.00 54.35 ? 306 LYS C C 1 ATOM 8825 O O . LYS C 1 273 ? -26.212 78.926 44.785 1.00 54.20 ? 306 LYS C O 1 ATOM 8826 C CB . LYS C 1 273 ? -28.908 79.277 43.686 1.00 63.66 ? 306 LYS C CB 1 ATOM 8827 C CG . LYS C 1 273 ? -29.329 79.738 45.088 1.00 72.32 ? 306 LYS C CG 1 ATOM 8828 C CD . LYS C 1 273 ? -30.519 80.712 45.093 1.00 74.85 ? 306 LYS C CD 1 ATOM 8829 C CE . LYS C 1 273 ? -30.195 82.079 44.492 1.00 77.01 ? 306 LYS C CE 1 ATOM 8830 N NZ . LYS C 1 273 ? -29.424 82.956 45.422 1.00 78.16 1 306 LYS C NZ 1 ATOM 8831 N N . GLY C 1 274 ? -25.545 78.645 42.639 1.00 47.17 ? 307 GLY C N 1 ATOM 8832 C CA . GLY C 1 274 ? -24.334 77.833 42.968 1.00 41.95 ? 307 GLY C CA 1 ATOM 8833 C C . GLY C 1 274 ? -24.509 76.302 43.008 1.00 41.24 ? 307 GLY C C 1 ATOM 8834 O O . GLY C 1 274 ? -23.594 75.551 43.348 1.00 37.93 ? 307 GLY C O 1 ATOM 8835 N N . SER C 1 275 ? -25.695 75.834 42.649 1.00 39.16 ? 308 SER C N 1 ATOM 8836 C CA . SER C 1 275 ? -25.988 74.419 42.545 1.00 35.99 ? 308 SER C CA 1 ATOM 8837 C C . SER C 1 275 ? -25.629 73.871 41.148 1.00 32.83 ? 308 SER C C 1 ATOM 8838 O O . SER C 1 275 ? -25.897 74.517 40.138 1.00 30.63 ? 308 SER C O 1 ATOM 8839 C CB . SER C 1 275 ? -27.483 74.235 42.767 1.00 37.96 ? 308 SER C CB 1 ATOM 8840 O OG . SER C 1 275 ? -27.735 72.922 43.186 1.00 43.84 ? 308 SER C OG 1 ATOM 8841 N N . PRO C 1 276 ? -25.048 72.661 41.085 1.00 30.06 ? 309 PRO C N 1 ATOM 8842 C CA . PRO C 1 276 ? -24.580 72.138 39.809 1.00 27.86 ? 309 PRO C CA 1 ATOM 8843 C C . PRO C 1 276 ? -25.711 71.534 38.998 1.00 27.42 ? 309 PRO C C 1 ATOM 8844 O O . PRO C 1 276 ? -26.416 70.646 39.482 1.00 28.77 ? 309 PRO C O 1 ATOM 8845 C CB . PRO C 1 276 ? -23.567 71.067 40.222 1.00 27.60 ? 309 PRO C CB 1 ATOM 8846 C CG . PRO C 1 276 ? -24.042 70.606 41.558 1.00 28.36 ? 309 PRO C CG 1 ATOM 8847 C CD . PRO C 1 276 ? -24.678 71.785 42.216 1.00 29.38 ? 309 PRO C CD 1 ATOM 8848 N N . VAL C 1 277 ? -25.830 71.974 37.746 1.00 25.31 ? 310 VAL C N 1 ATOM 8849 C CA . VAL C 1 277 ? -26.992 71.660 36.888 1.00 24.05 ? 310 VAL C CA 1 ATOM 8850 C C . VAL C 1 277 ? -26.664 71.116 35.492 1.00 22.98 ? 310 VAL C C 1 ATOM 8851 O O . VAL C 1 277 ? -27.546 70.513 34.883 1.00 22.66 ? 310 VAL C O 1 ATOM 8852 C CB . VAL C 1 277 ? -27.899 72.914 36.693 1.00 23.67 ? 310 VAL C CB 1 ATOM 8853 C CG1 . VAL C 1 277 ? -28.496 73.293 38.039 1.00 24.06 ? 310 VAL C CG1 1 ATOM 8854 C CG2 . VAL C 1 277 ? -27.121 74.087 36.057 1.00 22.00 ? 310 VAL C CG2 1 ATOM 8855 N N . ASN C 1 278 ? -25.450 71.367 34.966 1.00 21.35 ? 311 ASN C N 1 ATOM 8856 C CA . ASN C 1 278 ? -25.080 70.836 33.654 1.00 18.57 ? 311 ASN C CA 1 ATOM 8857 C C . ASN C 1 278 ? -23.681 70.329 33.609 1.00 17.91 ? 311 ASN C C 1 ATOM 8858 O O . ASN C 1 278 ? -22.815 70.928 34.181 1.00 18.05 ? 311 ASN C O 1 ATOM 8859 C CB . ASN C 1 278 ? -25.265 71.862 32.559 1.00 17.72 ? 311 ASN C CB 1 ATOM 8860 C CG . ASN C 1 278 ? -26.299 71.440 31.556 1.00 17.96 ? 311 ASN C CG 1 ATOM 8861 O OD1 . ASN C 1 278 ? -26.094 71.531 30.348 1.00 20.25 ? 311 ASN C OD1 1 ATOM 8862 N ND2 . ASN C 1 278 ? -27.426 70.987 32.038 1.00 17.53 ? 311 ASN C ND2 1 ATOM 8863 N N . SER C 1 279 ? -23.516 69.202 32.895 1.00 17.90 ? 312 SER C N 1 ATOM 8864 C CA . SER C 1 279 ? -22.270 68.465 32.623 1.00 15.54 ? 312 SER C CA 1 ATOM 8865 C C . SER C 1 279 ? -21.769 68.830 31.188 1.00 15.70 ? 312 SER C C 1 ATOM 8866 O O . SER C 1 279 ? -22.525 68.634 30.211 1.00 17.97 ? 312 SER C O 1 ATOM 8867 C CB . SER C 1 279 ? -22.576 66.978 32.742 1.00 14.69 ? 312 SER C CB 1 ATOM 8868 O OG . SER C 1 279 ? -22.656 66.522 34.106 1.00 14.31 ? 312 SER C OG 1 ATOM 8869 N N . LEU C 1 280 ? -20.544 69.387 31.055 1.00 14.67 ? 313 LEU C N 1 ATOM 8870 C CA . LEU C 1 280 ? -19.912 69.710 29.765 1.00 13.48 ? 313 LEU C CA 1 ATOM 8871 C C . LEU C 1 280 ? -18.658 68.846 29.569 1.00 13.69 ? 313 LEU C C 1 ATOM 8872 O O . LEU C 1 280 ? -17.817 68.773 30.461 1.00 13.22 ? 313 LEU C O 1 ATOM 8873 C CB . LEU C 1 280 ? -19.490 71.188 29.680 1.00 13.16 ? 313 LEU C CB 1 ATOM 8874 C CG . LEU C 1 280 ? -20.581 72.269 29.671 1.00 13.46 ? 313 LEU C CG 1 ATOM 8875 C CD1 . LEU C 1 280 ? -21.319 72.179 31.011 1.00 13.79 ? 313 LEU C CD1 1 ATOM 8876 C CD2 . LEU C 1 280 ? -20.087 73.688 29.423 1.00 12.57 ? 313 LEU C CD2 1 ATOM 8877 N N . PHE C 1 281 ? -18.502 68.282 28.364 1.00 13.77 ? 314 PHE C N 1 ATOM 8878 C CA . PHE C 1 281 ? -17.397 67.390 28.005 1.00 13.08 ? 314 PHE C CA 1 ATOM 8879 C C . PHE C 1 281 ? -16.597 67.845 26.782 1.00 12.97 ? 314 PHE C C 1 ATOM 8880 O O . PHE C 1 281 ? -17.133 67.898 25.656 1.00 14.49 ? 314 PHE C O 1 ATOM 8881 C CB . PHE C 1 281 ? -17.992 66.009 27.758 1.00 13.02 ? 314 PHE C CB 1 ATOM 8882 C CG . PHE C 1 281 ? -18.727 65.485 28.931 1.00 12.80 ? 314 PHE C CG 1 ATOM 8883 C CD1 . PHE C 1 281 ? -18.061 64.845 29.926 1.00 12.95 ? 314 PHE C CD1 1 ATOM 8884 C CD2 . PHE C 1 281 ? -20.057 65.704 29.067 1.00 12.59 ? 314 PHE C CD2 1 ATOM 8885 C CE1 . PHE C 1 281 ? -18.725 64.427 31.057 1.00 13.71 ? 314 PHE C CE1 1 ATOM 8886 C CE2 . PHE C 1 281 ? -20.752 65.237 30.175 1.00 13.18 ? 314 PHE C CE2 1 ATOM 8887 C CZ . PHE C 1 281 ? -20.078 64.619 31.189 1.00 13.54 ? 314 PHE C CZ 1 ATOM 8888 N N . VAL C 1 282 ? -15.328 68.153 26.964 1.00 11.94 ? 315 VAL C N 1 ATOM 8889 C CA . VAL C 1 282 ? -14.574 68.670 25.865 1.00 11.88 ? 315 VAL C CA 1 ATOM 8890 C C . VAL C 1 282 ? -13.711 67.522 25.407 1.00 12.88 ? 315 VAL C C 1 ATOM 8891 O O . VAL C 1 282 ? -12.979 66.885 26.189 1.00 13.95 ? 315 VAL C O 1 ATOM 8892 C CB . VAL C 1 282 ? -13.713 69.841 26.295 1.00 11.64 ? 315 VAL C CB 1 ATOM 8893 C CG1 . VAL C 1 282 ? -12.750 70.202 25.208 1.00 12.09 ? 315 VAL C CG1 1 ATOM 8894 C CG2 . VAL C 1 282 ? -14.577 71.008 26.647 1.00 11.55 ? 315 VAL C CG2 1 ATOM 8895 N N . ALA C 1 283 ? -13.749 67.248 24.125 1.00 13.51 ? 316 ALA C N 1 ATOM 8896 C CA . ALA C 1 283 ? -13.127 65.999 23.648 1.00 13.50 ? 316 ALA C CA 1 ATOM 8897 C C . ALA C 1 283 ? -11.796 66.411 22.988 1.00 14.15 ? 316 ALA C C 1 ATOM 8898 O O . ALA C 1 283 ? -11.654 67.486 22.377 1.00 13.60 ? 316 ALA C O 1 ATOM 8899 C CB . ALA C 1 283 ? -14.068 65.271 22.695 1.00 12.46 ? 316 ALA C CB 1 ATOM 8900 N N . PRO C 1 284 ? -10.794 65.586 23.143 1.00 14.80 ? 317 PRO C N 1 ATOM 8901 C CA . PRO C 1 284 ? -9.532 65.961 22.560 1.00 13.95 ? 317 PRO C CA 1 ATOM 8902 C C . PRO C 1 284 ? -9.480 65.426 21.098 1.00 12.89 ? 317 PRO C C 1 ATOM 8903 O O . PRO C 1 284 ? -10.252 64.578 20.715 1.00 11.74 ? 317 PRO C O 1 ATOM 8904 C CB . PRO C 1 284 ? -8.515 65.207 23.467 1.00 14.22 ? 317 PRO C CB 1 ATOM 8905 C CG . PRO C 1 284 ? -9.265 63.981 23.973 1.00 14.57 ? 317 PRO C CG 1 ATOM 8906 C CD . PRO C 1 284 ? -10.750 64.207 23.675 1.00 15.43 ? 317 PRO C CD 1 ATOM 8907 N N . ALA C 1 285 ? -8.500 65.891 20.373 1.00 12.25 ? 318 ALA C N 1 ATOM 8908 C CA . ALA C 1 285 ? -8.457 65.804 18.974 1.00 13.61 ? 318 ALA C CA 1 ATOM 8909 C C . ALA C 1 285 ? -7.921 64.429 18.463 1.00 13.13 ? 318 ALA C C 1 ATOM 8910 O O . ALA C 1 285 ? -7.276 63.642 19.251 1.00 12.20 ? 318 ALA C O 1 ATOM 8911 C CB . ALA C 1 285 ? -7.604 66.982 18.418 1.00 14.64 ? 318 ALA C CB 1 ATOM 8912 N N . VAL C 1 286 ? -8.205 64.138 17.176 1.00 11.12 ? 319 VAL C N 1 ATOM 8913 C CA . VAL C 1 286 ? -7.447 63.037 16.496 1.00 10.96 ? 319 VAL C CA 1 ATOM 8914 C C . VAL C 1 286 ? -5.996 63.464 16.099 1.00 9.70 ? 319 VAL C C 1 ATOM 8915 O O . VAL C 1 286 ? -5.032 62.693 16.244 1.00 8.88 ? 319 VAL C O 1 ATOM 8916 C CB . VAL C 1 286 ? -8.247 62.435 15.279 1.00 11.19 ? 319 VAL C CB 1 ATOM 8917 C CG1 . VAL C 1 286 ? -7.468 61.396 14.469 1.00 11.82 ? 319 VAL C CG1 1 ATOM 8918 C CG2 . VAL C 1 286 ? -9.556 61.838 15.779 1.00 11.71 ? 319 VAL C CG2 1 ATOM 8919 N N . THR C 1 287 ? -5.867 64.677 15.535 1.00 8.96 ? 320 THR C N 1 ATOM 8920 C CA . THR C 1 287 ? -4.579 65.167 15.128 1.00 8.06 ? 320 THR C CA 1 ATOM 8921 C C . THR C 1 287 ? -3.709 65.311 16.371 1.00 8.42 ? 320 THR C C 1 ATOM 8922 O O . THR C 1 287 ? -4.172 65.702 17.444 1.00 8.31 ? 320 THR C O 1 ATOM 8923 C CB . THR C 1 287 ? -4.605 66.476 14.449 1.00 7.64 ? 320 THR C CB 1 ATOM 8924 O OG1 . THR C 1 287 ? -3.277 66.833 14.169 1.00 7.21 ? 320 THR C OG1 1 ATOM 8925 C CG2 . THR C 1 287 ? -5.165 67.612 15.371 1.00 8.12 ? 320 THR C CG2 1 ATOM 8926 N N . PRO C 1 288 ? -2.439 65.021 16.228 1.00 8.79 ? 321 PRO C N 1 ATOM 8927 C CA . PRO C 1 288 ? -1.539 65.174 17.316 1.00 9.48 ? 321 PRO C CA 1 ATOM 8928 C C . PRO C 1 288 ? -0.727 66.429 17.298 1.00 9.91 ? 321 PRO C C 1 ATOM 8929 O O . PRO C 1 288 ? 0.134 66.591 18.146 1.00 9.59 ? 321 PRO C O 1 ATOM 8930 C CB . PRO C 1 288 ? -0.619 63.997 17.098 1.00 9.80 ? 321 PRO C CB 1 ATOM 8931 C CG . PRO C 1 288 ? -0.552 63.964 15.590 1.00 9.53 ? 321 PRO C CG 1 ATOM 8932 C CD . PRO C 1 288 ? -1.895 64.202 15.138 1.00 8.85 ? 321 PRO C CD 1 ATOM 8933 N N . VAL C 1 289 ? -0.987 67.293 16.334 1.00 11.32 ? 322 VAL C N 1 ATOM 8934 C CA . VAL C 1 289 ? -0.109 68.396 16.033 1.00 13.31 ? 322 VAL C CA 1 ATOM 8935 C C . VAL C 1 289 ? 0.234 69.291 17.277 1.00 15.40 ? 322 VAL C C 1 ATOM 8936 O O . VAL C 1 289 ? -0.708 69.713 18.013 1.00 17.10 ? 322 VAL C O 1 ATOM 8937 C CB . VAL C 1 289 ? -0.744 69.342 14.921 1.00 13.39 ? 322 VAL C CB 1 ATOM 8938 C CG1 . VAL C 1 289 ? -1.998 70.075 15.408 1.00 13.16 ? 322 VAL C CG1 1 ATOM 8939 C CG2 . VAL C 1 289 ? 0.254 70.420 14.523 1.00 13.57 ? 322 VAL C CG2 1 ATOM 8940 N N . LYS C 1 290 ? 1.510 69.671 17.445 1.00 16.05 ? 323 LYS C N 1 ATOM 8941 C CA . LYS C 1 290 ? 1.852 70.776 18.347 1.00 18.31 ? 323 LYS C CA 1 ATOM 8942 C C . LYS C 1 290 ? 2.843 71.763 17.696 1.00 20.29 ? 323 LYS C C 1 ATOM 8943 O O . LYS C 1 290 ? 3.382 71.491 16.591 1.00 23.11 ? 323 LYS C O 1 ATOM 8944 C CB . LYS C 1 290 ? 2.438 70.230 19.673 1.00 19.23 ? 323 LYS C CB 1 ATOM 8945 C CG . LYS C 1 290 ? 3.692 69.374 19.527 1.00 21.11 ? 323 LYS C CG 1 ATOM 8946 C CD . LYS C 1 290 ? 4.286 69.061 20.892 1.00 23.86 ? 323 LYS C CD 1 ATOM 8947 C CE . LYS C 1 290 ? 5.806 68.766 20.891 1.00 24.33 ? 323 LYS C CE 1 ATOM 8948 N NZ . LYS C 1 290 ? 6.682 69.960 20.704 1.00 24.30 1 323 LYS C NZ 1 ATOM 8949 N N . SER C 1 291 ? 3.075 72.895 18.364 1.00 19.04 ? 324 SER C N 1 ATOM 8950 C CA A SER C 1 291 ? 4.182 73.788 18.029 0.50 20.46 ? 324 SER C CA 1 ATOM 8951 C CA B SER C 1 291 ? 4.179 73.782 18.021 0.50 20.30 ? 324 SER C CA 1 ATOM 8952 C C . SER C 1 291 ? 5.498 73.243 18.594 1.00 22.13 ? 324 SER C C 1 ATOM 8953 O O . SER C 1 291 ? 5.514 72.467 19.585 1.00 22.56 ? 324 SER C O 1 ATOM 8954 C CB A SER C 1 291 ? 3.981 75.175 18.660 0.50 20.94 ? 324 SER C CB 1 ATOM 8955 C CB B SER C 1 291 ? 3.920 75.194 18.580 0.50 20.63 ? 324 SER C CB 1 ATOM 8956 O OG A SER C 1 291 ? 2.826 75.844 18.188 0.50 20.99 ? 324 SER C OG 1 ATOM 8957 O OG B SER C 1 291 ? 5.096 75.799 19.096 0.50 20.21 ? 324 SER C OG 1 ATOM 8958 N N . VAL C 1 292 ? 6.627 73.685 18.023 1.00 23.32 ? 325 VAL C N 1 ATOM 8959 C CA . VAL C 1 292 ? 7.933 73.206 18.538 1.00 20.48 ? 325 VAL C CA 1 ATOM 8960 C C . VAL C 1 292 ? 8.216 73.594 19.977 1.00 18.04 ? 325 VAL C C 1 ATOM 8961 O O . VAL C 1 292 ? 8.834 72.855 20.708 1.00 14.84 ? 325 VAL C O 1 ATOM 8962 C CB . VAL C 1 292 ? 9.120 73.710 17.752 1.00 21.15 ? 325 VAL C CB 1 ATOM 8963 C CG1 . VAL C 1 292 ? 10.323 72.813 18.119 1.00 21.65 ? 325 VAL C CG1 1 ATOM 8964 C CG2 . VAL C 1 292 ? 8.785 73.760 16.262 1.00 20.88 ? 325 VAL C CG2 1 ATOM 8965 N N . LEU C 1 293 ? 7.774 74.774 20.360 1.00 17.71 ? 326 LEU C N 1 ATOM 8966 C CA . LEU C 1 293 ? 8.059 75.249 21.677 1.00 18.32 ? 326 LEU C CA 1 ATOM 8967 C C . LEU C 1 293 ? 7.170 74.648 22.739 1.00 17.27 ? 326 LEU C C 1 ATOM 8968 O O . LEU C 1 293 ? 7.512 74.766 23.947 1.00 16.77 ? 326 LEU C O 1 ATOM 8969 C CB . LEU C 1 293 ? 7.957 76.761 21.735 1.00 20.41 ? 326 LEU C CB 1 ATOM 8970 C CG . LEU C 1 293 ? 8.999 77.509 20.917 1.00 24.13 ? 326 LEU C CG 1 ATOM 8971 C CD1 . LEU C 1 293 ? 9.129 78.932 21.441 1.00 27.09 ? 326 LEU C CD1 1 ATOM 8972 C CD2 . LEU C 1 293 ? 10.363 76.820 20.967 1.00 25.39 ? 326 LEU C CD2 1 ATOM 8973 N N . GLU C 1 294 ? 6.060 73.994 22.353 1.00 16.80 ? 327 GLU C N 1 ATOM 8974 C CA . GLU C 1 294 ? 5.234 73.309 23.386 1.00 15.59 ? 327 GLU C CA 1 ATOM 8975 C C . GLU C 1 294 ? 5.892 72.043 23.894 1.00 13.87 ? 327 GLU C C 1 ATOM 8976 O O . GLU C 1 294 ? 6.312 71.250 23.138 1.00 12.82 ? 327 GLU C O 1 ATOM 8977 C CB . GLU C 1 294 ? 3.862 73.009 22.867 1.00 16.13 ? 327 GLU C CB 1 ATOM 8978 C CG . GLU C 1 294 ? 3.112 74.270 22.724 1.00 18.32 ? 327 GLU C CG 1 ATOM 8979 C CD . GLU C 1 294 ? 1.867 74.156 21.882 1.00 22.23 ? 327 GLU C CD 1 ATOM 8980 O OE1 . GLU C 1 294 ? 0.878 74.704 22.374 1.00 31.79 ? 327 GLU C OE1 1 ATOM 8981 O OE2 . GLU C 1 294 ? 1.835 73.619 20.745 1.00 22.92 -1 327 GLU C OE2 1 ATOM 8982 N N . LYS C 1 295 ? 5.988 71.854 25.185 1.00 14.53 ? 328 LYS C N 1 ATOM 8983 C CA . LYS C 1 295 ? 6.377 70.554 25.711 1.00 16.32 ? 328 LYS C CA 1 ATOM 8984 C C . LYS C 1 295 ? 5.386 69.420 25.444 1.00 16.35 ? 328 LYS C C 1 ATOM 8985 O O . LYS C 1 295 ? 5.766 68.276 25.102 1.00 17.39 ? 328 LYS C O 1 ATOM 8986 C CB . LYS C 1 295 ? 6.511 70.628 27.216 1.00 19.26 ? 328 LYS C CB 1 ATOM 8987 C CG . LYS C 1 295 ? 6.741 69.247 27.883 1.00 22.63 ? 328 LYS C CG 1 ATOM 8988 C CD . LYS C 1 295 ? 7.964 68.483 27.347 1.00 24.73 ? 328 LYS C CD 1 ATOM 8989 C CE . LYS C 1 295 ? 8.041 67.034 27.861 1.00 25.82 ? 328 LYS C CE 1 ATOM 8990 N NZ . LYS C 1 295 ? 7.075 66.114 27.143 1.00 26.96 1 328 LYS C NZ 1 ATOM 8991 N N . GLN C 1 296 ? 4.112 69.683 25.697 1.00 15.77 ? 329 GLN C N 1 ATOM 8992 C CA . GLN C 1 296 ? 3.115 68.613 25.657 1.00 15.24 ? 329 GLN C CA 1 ATOM 8993 C C . GLN C 1 296 ? 2.278 68.748 24.384 1.00 15.01 ? 329 GLN C C 1 ATOM 8994 O O . GLN C 1 296 ? 2.210 69.822 23.810 1.00 14.82 ? 329 GLN C O 1 ATOM 8995 C CB . GLN C 1 296 ? 2.272 68.658 26.959 1.00 15.27 ? 329 GLN C CB 1 ATOM 8996 C CG . GLN C 1 296 ? 3.036 68.201 28.213 1.00 14.98 ? 329 GLN C CG 1 ATOM 8997 C CD . GLN C 1 296 ? 3.341 66.717 28.127 1.00 16.26 ? 329 GLN C CD 1 ATOM 8998 O OE1 . GLN C 1 296 ? 4.389 66.290 27.690 1.00 16.93 ? 329 GLN C OE1 1 ATOM 8999 N NE2 . GLN C 1 296 ? 2.375 65.916 28.491 1.00 17.96 ? 329 GLN C NE2 1 ATOM 9000 N N . THR C 1 297 ? 1.607 67.676 23.998 1.00 14.76 ? 330 THR C N 1 ATOM 9001 C CA . THR C 1 297 ? 0.537 67.705 23.015 1.00 14.78 ? 330 THR C CA 1 ATOM 9002 C C . THR C 1 297 ? -0.453 66.628 23.366 1.00 14.27 ? 330 THR C C 1 ATOM 9003 O O . THR C 1 297 ? -0.320 66.068 24.403 1.00 14.59 ? 330 THR C O 1 ATOM 9004 C CB . THR C 1 297 ? 1.048 67.524 21.579 1.00 16.33 ? 330 THR C CB 1 ATOM 9005 O OG1 . THR C 1 297 ? -0.082 67.668 20.701 1.00 16.23 ? 330 THR C OG1 1 ATOM 9006 C CG2 . THR C 1 297 ? 1.799 66.141 21.369 1.00 15.71 ? 330 THR C CG2 1 ATOM 9007 N N . ASN C 1 298 ? -1.377 66.275 22.490 1.00 14.20 ? 331 ASN C N 1 ATOM 9008 C CA . ASN C 1 298 ? -2.246 65.117 22.748 1.00 14.79 ? 331 ASN C CA 1 ATOM 9009 C C . ASN C 1 298 ? -1.948 63.959 21.851 1.00 15.06 ? 331 ASN C C 1 ATOM 9010 O O . ASN C 1 298 ? -1.600 64.183 20.661 1.00 15.63 ? 331 ASN C O 1 ATOM 9011 C CB . ASN C 1 298 ? -3.733 65.427 22.603 1.00 15.38 ? 331 ASN C CB 1 ATOM 9012 C CG . ASN C 1 298 ? -4.077 65.928 21.252 1.00 15.31 ? 331 ASN C CG 1 ATOM 9013 O OD1 . ASN C 1 298 ? -3.559 66.868 20.827 1.00 18.36 ? 331 ASN C OD1 1 ATOM 9014 N ND2 . ASN C 1 298 ? -4.930 65.318 20.622 1.00 16.37 ? 331 ASN C ND2 1 ATOM 9015 N N . ASN C 1 299 ? -2.145 62.726 22.395 1.00 12.19 ? 332 ASN C N 1 ATOM 9016 C CA . ASN C 1 299 ? -2.182 61.550 21.527 1.00 10.93 ? 332 ASN C CA 1 ATOM 9017 C C . ASN C 1 299 ? -3.560 61.628 20.869 1.00 10.23 ? 332 ASN C C 1 ATOM 9018 O O . ASN C 1 299 ? -4.472 62.208 21.396 1.00 10.64 ? 332 ASN C O 1 ATOM 9019 C CB . ASN C 1 299 ? -2.136 60.273 22.290 1.00 10.99 ? 332 ASN C CB 1 ATOM 9020 C CG . ASN C 1 299 ? -0.749 59.810 22.570 1.00 11.60 ? 332 ASN C CG 1 ATOM 9021 O OD1 . ASN C 1 299 ? -0.464 59.421 23.707 1.00 12.87 ? 332 ASN C OD1 1 ATOM 9022 N ND2 . ASN C 1 299 ? 0.119 59.824 21.568 1.00 10.39 ? 332 ASN C ND2 1 ATOM 9023 N N . PRO C 1 300 ? -3.731 61.073 19.720 1.00 9.44 ? 333 PRO C N 1 ATOM 9024 C CA . PRO C 1 300 ? -5.093 61.043 19.151 1.00 9.79 ? 333 PRO C CA 1 ATOM 9025 C C . PRO C 1 300 ? -6.152 60.271 20.064 1.00 10.90 ? 333 PRO C C 1 ATOM 9026 O O . PRO C 1 300 ? -5.811 59.284 20.790 1.00 8.89 ? 333 PRO C O 1 ATOM 9027 C CB . PRO C 1 300 ? -4.900 60.324 17.860 1.00 9.51 ? 333 PRO C CB 1 ATOM 9028 C CG . PRO C 1 300 ? -3.390 60.311 17.638 1.00 9.09 ? 333 PRO C CG 1 ATOM 9029 C CD . PRO C 1 300 ? -2.715 60.403 18.924 1.00 8.63 ? 333 PRO C CD 1 ATOM 9030 N N . GLY C 1 301 ? -7.403 60.827 20.032 1.00 12.08 ? 334 GLY C N 1 ATOM 9031 C CA . GLY C 1 301 ? -8.531 60.379 20.813 1.00 12.52 ? 334 GLY C CA 1 ATOM 9032 C C . GLY C 1 301 ? -9.864 60.093 20.058 1.00 14.14 ? 334 GLY C C 1 ATOM 9033 O O . GLY C 1 301 ? -10.303 60.832 19.167 1.00 14.38 ? 334 GLY C O 1 ATOM 9034 N N . ILE C 1 302 ? -10.536 59.026 20.468 1.00 14.13 ? 335 ILE C N 1 ATOM 9035 C CA . ILE C 1 302 ? -11.849 58.699 19.992 1.00 15.78 ? 335 ILE C CA 1 ATOM 9036 C C . ILE C 1 302 ? -12.646 58.596 21.269 1.00 17.91 ? 335 ILE C C 1 ATOM 9037 O O . ILE C 1 302 ? -12.128 57.978 22.250 1.00 20.37 ? 335 ILE C O 1 ATOM 9038 C CB . ILE C 1 302 ? -11.891 57.262 19.357 1.00 16.13 ? 335 ILE C CB 1 ATOM 9039 C CG1 . ILE C 1 302 ? -11.159 57.232 18.060 1.00 17.63 ? 335 ILE C CG1 1 ATOM 9040 C CG2 . ILE C 1 302 ? -13.340 56.837 19.099 1.00 16.77 ? 335 ILE C CG2 1 ATOM 9041 C CD1 . ILE C 1 302 ? -11.346 58.618 17.359 1.00 19.57 ? 335 ILE C CD1 1 ATOM 9042 N N . ARG C 1 303 ? -13.902 59.088 21.309 1.00 16.88 ? 336 ARG C N 1 ATOM 9043 C CA . ARG C 1 303 ? -14.679 58.690 22.470 1.00 17.32 ? 336 ARG C CA 1 ATOM 9044 C C . ARG C 1 303 ? -16.106 58.169 22.274 1.00 17.80 ? 336 ARG C C 1 ATOM 9045 O O . ARG C 1 303 ? -16.840 58.597 21.361 1.00 19.32 ? 336 ARG C O 1 ATOM 9046 C CB . ARG C 1 303 ? -14.608 59.750 23.554 1.00 16.91 ? 336 ARG C CB 1 ATOM 9047 C CG . ARG C 1 303 ? -15.292 61.056 23.176 1.00 16.48 ? 336 ARG C CG 1 ATOM 9048 C CD . ARG C 1 303 ? -15.426 61.980 24.407 1.00 15.28 ? 336 ARG C CD 1 ATOM 9049 N NE . ARG C 1 303 ? -14.194 62.225 25.155 1.00 14.07 ? 336 ARG C NE 1 ATOM 9050 C CZ . ARG C 1 303 ? -14.053 63.168 26.088 1.00 14.48 ? 336 ARG C CZ 1 ATOM 9051 N NH1 . ARG C 1 303 ? -15.021 64.056 26.337 1.00 14.78 1 336 ARG C NH1 1 ATOM 9052 N NH2 . ARG C 1 303 ? -12.918 63.276 26.772 1.00 14.48 ? 336 ARG C NH2 1 ATOM 9053 N N . LEU C 1 304 ? -16.456 57.269 23.193 1.00 16.31 ? 337 LEU C N 1 ATOM 9054 C CA . LEU C 1 304 ? -17.751 56.679 23.279 1.00 17.03 ? 337 LEU C CA 1 ATOM 9055 C C . LEU C 1 304 ? -18.559 56.932 24.583 1.00 16.08 ? 337 LEU C C 1 ATOM 9056 O O . LEU C 1 304 ? -18.119 56.555 25.737 1.00 13.39 ? 337 LEU C O 1 ATOM 9057 C CB . LEU C 1 304 ? -17.535 55.188 23.149 1.00 19.41 ? 337 LEU C CB 1 ATOM 9058 C CG . LEU C 1 304 ? -18.749 54.251 23.039 1.00 20.71 ? 337 LEU C CG 1 ATOM 9059 C CD1 . LEU C 1 304 ? -19.264 54.355 21.629 1.00 20.89 ? 337 LEU C CD1 1 ATOM 9060 C CD2 . LEU C 1 304 ? -18.401 52.788 23.400 1.00 21.56 ? 337 LEU C CD2 1 ATOM 9061 N N . PHE C 1 305 ? -19.783 57.466 24.384 1.00 14.91 ? 338 PHE C N 1 ATOM 9062 C CA . PHE C 1 305 ? -20.643 57.835 25.540 1.00 14.28 ? 338 PHE C CA 1 ATOM 9063 C C . PHE C 1 305 ? -21.746 56.822 25.719 1.00 14.01 ? 338 PHE C C 1 ATOM 9064 O O . PHE C 1 305 ? -22.249 56.304 24.762 1.00 13.11 ? 338 PHE C O 1 ATOM 9065 C CB . PHE C 1 305 ? -21.306 59.215 25.382 1.00 14.06 ? 338 PHE C CB 1 ATOM 9066 C CG . PHE C 1 305 ? -20.441 60.359 25.740 1.00 13.13 ? 338 PHE C CG 1 ATOM 9067 C CD1 . PHE C 1 305 ? -20.395 60.801 27.019 1.00 13.11 ? 338 PHE C CD1 1 ATOM 9068 C CD2 . PHE C 1 305 ? -19.689 61.002 24.777 1.00 12.76 ? 338 PHE C CD2 1 ATOM 9069 C CE1 . PHE C 1 305 ? -19.591 61.870 27.372 1.00 12.90 ? 338 PHE C CE1 1 ATOM 9070 C CE2 . PHE C 1 305 ? -18.860 62.058 25.118 1.00 13.26 ? 338 PHE C CE2 1 ATOM 9071 C CZ . PHE C 1 305 ? -18.816 62.505 26.428 1.00 12.86 ? 338 PHE C CZ 1 ATOM 9072 N N . GLN C 1 306 ? -22.103 56.598 26.970 1.00 14.52 ? 339 GLN C N 1 ATOM 9073 C CA . GLN C 1 306 ? -23.169 55.693 27.372 1.00 16.69 ? 339 GLN C CA 1 ATOM 9074 C C . GLN C 1 306 ? -24.313 56.490 27.997 1.00 18.43 ? 339 GLN C C 1 ATOM 9075 O O . GLN C 1 306 ? -24.089 57.354 28.883 1.00 17.48 ? 339 GLN C O 1 ATOM 9076 C CB . GLN C 1 306 ? -22.692 54.639 28.373 1.00 16.47 ? 339 GLN C CB 1 ATOM 9077 C CG . GLN C 1 306 ? -21.879 53.548 27.705 1.00 17.45 ? 339 GLN C CG 1 ATOM 9078 C CD . GLN C 1 306 ? -21.270 52.525 28.662 1.00 18.96 ? 339 GLN C CD 1 ATOM 9079 O OE1 . GLN C 1 306 ? -21.166 52.704 29.911 1.00 20.38 ? 339 GLN C OE1 1 ATOM 9080 N NE2 . GLN C 1 306 ? -20.849 51.440 28.080 1.00 18.70 ? 339 GLN C NE2 1 ATOM 9081 N N . TYR C 1 307 ? -25.526 56.226 27.496 1.00 20.05 ? 340 TYR C N 1 ATOM 9082 C CA . TYR C 1 307 ? -26.689 56.908 27.976 1.00 21.81 ? 340 TYR C CA 1 ATOM 9083 C C . TYR C 1 307 ? -27.810 55.928 28.326 1.00 22.18 ? 340 TYR C C 1 ATOM 9084 O O . TYR C 1 307 ? -27.843 54.796 27.834 1.00 21.08 ? 340 TYR C O 1 ATOM 9085 C CB . TYR C 1 307 ? -27.169 57.981 26.983 1.00 23.24 ? 340 TYR C CB 1 ATOM 9086 C CG . TYR C 1 307 ? -27.669 57.474 25.629 1.00 24.06 ? 340 TYR C CG 1 ATOM 9087 C CD1 . TYR C 1 307 ? -26.782 57.252 24.598 1.00 24.43 ? 340 TYR C CD1 1 ATOM 9088 C CD2 . TYR C 1 307 ? -29.039 57.301 25.361 1.00 23.61 ? 340 TYR C CD2 1 ATOM 9089 C CE1 . TYR C 1 307 ? -27.235 56.874 23.344 1.00 24.99 ? 340 TYR C CE1 1 ATOM 9090 C CE2 . TYR C 1 307 ? -29.480 56.865 24.108 1.00 23.30 ? 340 TYR C CE2 1 ATOM 9091 C CZ . TYR C 1 307 ? -28.566 56.658 23.118 1.00 22.16 ? 340 TYR C CZ 1 ATOM 9092 O OH . TYR C 1 307 ? -28.889 56.176 21.912 1.00 20.22 ? 340 TYR C OH 1 ATOM 9093 N N . ASP C 1 308 ? -28.686 56.396 29.218 1.00 21.03 ? 341 ASP C N 1 ATOM 9094 C CA . ASP C 1 308 ? -29.925 55.751 29.537 1.00 20.36 ? 341 ASP C CA 1 ATOM 9095 C C . ASP C 1 308 ? -30.926 56.253 28.510 1.00 21.08 ? 341 ASP C C 1 ATOM 9096 O O . ASP C 1 308 ? -31.221 57.480 28.455 1.00 20.13 ? 341 ASP C O 1 ATOM 9097 C CB . ASP C 1 308 ? -30.322 56.211 30.929 1.00 20.57 ? 341 ASP C CB 1 ATOM 9098 C CG . ASP C 1 308 ? -31.532 55.517 31.456 1.00 21.45 ? 341 ASP C CG 1 ATOM 9099 O OD1 . ASP C 1 308 ? -32.398 55.071 30.679 1.00 22.14 ? 341 ASP C OD1 1 ATOM 9100 O OD2 . ASP C 1 308 ? -31.626 55.438 32.692 1.00 23.11 -1 341 ASP C OD2 1 ATOM 9101 N N . PRO C 1 309 ? -31.461 55.349 27.690 1.00 20.81 ? 342 PRO C N 1 ATOM 9102 C CA . PRO C 1 309 ? -32.382 55.799 26.631 1.00 23.27 ? 342 PRO C CA 1 ATOM 9103 C C . PRO C 1 309 ? -33.845 56.156 27.053 1.00 23.32 ? 342 PRO C C 1 ATOM 9104 O O . PRO C 1 309 ? -34.650 56.500 26.188 1.00 25.78 ? 342 PRO C O 1 ATOM 9105 C CB . PRO C 1 309 ? -32.356 54.661 25.620 1.00 22.64 ? 342 PRO C CB 1 ATOM 9106 C CG . PRO C 1 309 ? -32.044 53.451 26.464 1.00 23.85 ? 342 PRO C CG 1 ATOM 9107 C CD . PRO C 1 309 ? -31.208 53.914 27.636 1.00 22.34 ? 342 PRO C CD 1 ATOM 9108 N N . ARG C 1 310 ? -34.161 56.146 28.339 1.00 22.84 ? 343 ARG C N 1 ATOM 9109 C CA . ARG C 1 310 ? -35.462 56.611 28.823 1.00 22.74 ? 343 ARG C CA 1 ATOM 9110 C C . ARG C 1 310 ? -35.448 58.121 29.008 1.00 23.26 ? 343 ARG C C 1 ATOM 9111 O O . ARG C 1 310 ? -36.230 58.817 28.393 1.00 24.34 ? 343 ARG C O 1 ATOM 9112 C CB . ARG C 1 310 ? -35.843 55.912 30.152 1.00 24.42 ? 343 ARG C CB 1 ATOM 9113 C CG . ARG C 1 310 ? -36.043 54.400 30.010 1.00 25.42 ? 343 ARG C CG 1 ATOM 9114 C CD . ARG C 1 310 ? -35.991 53.653 31.313 1.00 28.00 ? 343 ARG C CD 1 ATOM 9115 N NE . ARG C 1 310 ? -34.755 53.895 32.073 1.00 30.42 ? 343 ARG C NE 1 ATOM 9116 C CZ . ARG C 1 310 ? -34.457 53.331 33.248 1.00 28.79 ? 343 ARG C CZ 1 ATOM 9117 N NH1 . ARG C 1 310 ? -35.293 52.496 33.820 1.00 30.21 1 343 ARG C NH1 1 ATOM 9118 N NH2 . ARG C 1 310 ? -33.319 53.598 33.847 1.00 27.10 ? 343 ARG C NH2 1 ATOM 9119 N N . ASP C 1 311 ? -34.552 58.627 29.859 1.00 24.42 ? 344 ASP C N 1 ATOM 9120 C CA . ASP C 1 311 ? -34.385 60.090 30.100 1.00 23.51 ? 344 ASP C CA 1 ATOM 9121 C C . ASP C 1 311 ? -33.098 60.712 29.470 1.00 23.54 ? 344 ASP C C 1 ATOM 9122 O O . ASP C 1 311 ? -32.842 61.935 29.600 1.00 23.76 ? 344 ASP C O 1 ATOM 9123 C CB . ASP C 1 311 ? -34.425 60.399 31.606 1.00 22.05 ? 344 ASP C CB 1 ATOM 9124 C CG . ASP C 1 311 ? -33.316 59.750 32.355 1.00 22.91 ? 344 ASP C CG 1 ATOM 9125 O OD1 . ASP C 1 311 ? -32.475 59.109 31.721 1.00 22.78 ? 344 ASP C OD1 1 ATOM 9126 O OD2 . ASP C 1 311 ? -33.260 59.866 33.603 1.00 27.43 -1 344 ASP C OD2 1 ATOM 9127 N N . TYR C 1 312 ? -32.280 59.884 28.815 1.00 22.22 ? 345 TYR C N 1 ATOM 9128 C CA . TYR C 1 312 ? -31.051 60.399 28.145 1.00 22.74 ? 345 TYR C CA 1 ATOM 9129 C C . TYR C 1 312 ? -29.906 60.940 29.071 1.00 23.21 ? 345 TYR C C 1 ATOM 9130 O O . TYR C 1 312 ? -29.002 61.692 28.639 1.00 22.40 ? 345 TYR C O 1 ATOM 9131 C CB . TYR C 1 312 ? -31.503 61.377 27.040 1.00 20.98 ? 345 TYR C CB 1 ATOM 9132 C CG . TYR C 1 312 ? -32.461 60.624 26.053 1.00 19.38 ? 345 TYR C CG 1 ATOM 9133 C CD1 . TYR C 1 312 ? -31.983 59.592 25.281 1.00 17.40 ? 345 TYR C CD1 1 ATOM 9134 C CD2 . TYR C 1 312 ? -33.817 60.918 25.971 1.00 17.42 ? 345 TYR C CD2 1 ATOM 9135 C CE1 . TYR C 1 312 ? -32.797 58.926 24.447 1.00 17.94 ? 345 TYR C CE1 1 ATOM 9136 C CE2 . TYR C 1 312 ? -34.635 60.250 25.106 1.00 16.71 ? 345 TYR C CE2 1 ATOM 9137 C CZ . TYR C 1 312 ? -34.129 59.253 24.343 1.00 18.03 ? 345 TYR C CZ 1 ATOM 9138 O OH . TYR C 1 312 ? -34.930 58.511 23.436 1.00 21.13 ? 345 TYR C OH 1 ATOM 9139 N N . LYS C 1 313 ? -29.969 60.500 30.332 1.00 22.91 ? 346 LYS C N 1 ATOM 9140 C CA . LYS C 1 313 ? -28.954 60.732 31.344 1.00 24.72 ? 346 LYS C CA 1 ATOM 9141 C C . LYS C 1 313 ? -27.669 60.017 30.918 1.00 23.31 ? 346 LYS C C 1 ATOM 9142 O O . LYS C 1 313 ? -27.708 58.860 30.462 1.00 24.72 ? 346 LYS C O 1 ATOM 9143 C CB . LYS C 1 313 ? -29.473 60.228 32.724 1.00 27.85 ? 346 LYS C CB 1 ATOM 9144 C CG . LYS C 1 313 ? -28.396 59.855 33.752 1.00 33.21 ? 346 LYS C CG 1 ATOM 9145 C CD . LYS C 1 313 ? -28.889 59.685 35.201 1.00 36.49 ? 346 LYS C CD 1 ATOM 9146 C CE . LYS C 1 313 ? -29.557 58.341 35.518 1.00 38.76 ? 346 LYS C CE 1 ATOM 9147 N NZ . LYS C 1 313 ? -30.919 58.174 34.905 1.00 40.52 1 346 LYS C NZ 1 ATOM 9148 N N . LEU C 1 314 ? -26.543 60.718 31.029 1.00 21.29 ? 347 LEU C N 1 ATOM 9149 C CA . LEU C 1 314 ? -25.211 60.174 30.675 1.00 19.76 ? 347 LEU C CA 1 ATOM 9150 C C . LEU C 1 314 ? -24.733 59.239 31.772 1.00 19.24 ? 347 LEU C C 1 ATOM 9151 O O . LEU C 1 314 ? -24.589 59.641 32.939 1.00 19.13 ? 347 LEU C O 1 ATOM 9152 C CB . LEU C 1 314 ? -24.209 61.331 30.505 1.00 19.23 ? 347 LEU C CB 1 ATOM 9153 C CG . LEU C 1 314 ? -24.534 62.309 29.374 1.00 19.42 ? 347 LEU C CG 1 ATOM 9154 C CD1 . LEU C 1 314 ? -23.884 63.673 29.516 1.00 18.76 ? 347 LEU C CD1 1 ATOM 9155 C CD2 . LEU C 1 314 ? -24.126 61.629 28.073 1.00 20.75 ? 347 LEU C CD2 1 ATOM 9156 N N . LEU C 1 315 ? -24.500 57.988 31.417 1.00 18.56 ? 348 LEU C N 1 ATOM 9157 C CA . LEU C 1 315 ? -24.082 56.972 32.400 1.00 17.79 ? 348 LEU C CA 1 ATOM 9158 C C . LEU C 1 315 ? -22.593 56.873 32.479 1.00 16.65 ? 348 LEU C C 1 ATOM 9159 O O . LEU C 1 315 ? -22.041 56.674 33.529 1.00 16.80 ? 348 LEU C O 1 ATOM 9160 C CB . LEU C 1 315 ? -24.651 55.585 32.055 1.00 18.24 ? 348 LEU C CB 1 ATOM 9161 C CG . LEU C 1 315 ? -26.175 55.554 31.938 1.00 19.42 ? 348 LEU C CG 1 ATOM 9162 C CD1 . LEU C 1 315 ? -26.669 54.185 31.422 1.00 19.31 ? 348 LEU C CD1 1 ATOM 9163 C CD2 . LEU C 1 315 ? -26.791 55.970 33.298 1.00 18.88 ? 348 LEU C CD2 1 ATOM 9164 N N . ASP C 1 316 ? -21.925 57.012 31.373 1.00 16.59 ? 349 ASP C N 1 ATOM 9165 C CA . ASP C 1 316 ? -20.513 56.772 31.426 1.00 18.74 ? 349 ASP C CA 1 ATOM 9166 C C . ASP C 1 316 ? -19.800 57.207 30.127 1.00 18.23 ? 349 ASP C C 1 ATOM 9167 O O . ASP C 1 316 ? -20.434 57.724 29.202 1.00 16.27 ? 349 ASP C O 1 ATOM 9168 C CB . ASP C 1 316 ? -20.242 55.287 31.714 1.00 18.90 ? 349 ASP C CB 1 ATOM 9169 C CG . ASP C 1 316 ? -19.005 55.085 32.577 1.00 19.05 ? 349 ASP C CG 1 ATOM 9170 O OD1 . ASP C 1 316 ? -18.247 56.053 32.744 1.00 18.41 ? 349 ASP C OD1 1 ATOM 9171 O OD2 . ASP C 1 316 ? -18.790 53.950 33.059 1.00 20.51 -1 349 ASP C OD2 1 ATOM 9172 N N . MET C 1 317 ? -18.484 57.010 30.089 1.00 19.03 ? 350 MET C N 1 ATOM 9173 C CA . MET C 1 317 ? -17.684 57.460 28.961 1.00 19.95 ? 350 MET C CA 1 ATOM 9174 C C . MET C 1 317 ? -16.388 56.723 28.885 1.00 18.23 ? 350 MET C C 1 ATOM 9175 O O . MET C 1 317 ? -15.763 56.427 29.890 1.00 17.65 ? 350 MET C O 1 ATOM 9176 C CB . MET C 1 317 ? -17.411 58.986 29.065 1.00 21.37 ? 350 MET C CB 1 ATOM 9177 C CG . MET C 1 317 ? -16.987 59.622 27.743 1.00 22.50 ? 350 MET C CG 1 ATOM 9178 S SD . MET C 1 317 ? -15.252 59.927 27.542 1.00 21.63 ? 350 MET C SD 1 ATOM 9179 C CE . MET C 1 317 ? -15.270 61.397 28.523 1.00 20.32 ? 350 MET C CE 1 ATOM 9180 N N . LEU C 1 318 ? -16.010 56.440 27.658 1.00 18.38 ? 351 LEU C N 1 ATOM 9181 C CA . LEU C 1 318 ? -14.884 55.538 27.368 1.00 18.07 ? 351 LEU C CA 1 ATOM 9182 C C . LEU C 1 318 ? -14.042 56.321 26.444 1.00 15.55 ? 351 LEU C C 1 ATOM 9183 O O . LEU C 1 318 ? -14.552 56.787 25.445 1.00 13.90 ? 351 LEU C O 1 ATOM 9184 C CB . LEU C 1 318 ? -15.381 54.259 26.693 1.00 20.13 ? 351 LEU C CB 1 ATOM 9185 C CG . LEU C 1 318 ? -16.100 53.272 27.666 1.00 22.24 ? 351 LEU C CG 1 ATOM 9186 C CD1 . LEU C 1 318 ? -17.549 53.648 28.064 1.00 23.96 ? 351 LEU C CD1 1 ATOM 9187 C CD2 . LEU C 1 318 ? -16.075 51.865 27.054 1.00 22.64 ? 351 LEU C CD2 1 ATOM 9188 N N . GLN C 1 319 ? -12.794 56.563 26.842 1.00 15.05 ? 352 GLN C N 1 ATOM 9189 C CA . GLN C 1 319 ? -11.841 57.373 26.054 1.00 14.51 ? 352 GLN C CA 1 ATOM 9190 C C . GLN C 1 319 ? -10.826 56.486 25.425 1.00 14.05 ? 352 GLN C C 1 ATOM 9191 O O . GLN C 1 319 ? -10.188 55.715 26.074 1.00 14.24 ? 352 GLN C O 1 ATOM 9192 C CB . GLN C 1 319 ? -11.115 58.425 26.905 1.00 15.00 ? 352 GLN C CB 1 ATOM 9193 C CG . GLN C 1 319 ? -10.148 59.312 26.085 1.00 15.17 ? 352 GLN C CG 1 ATOM 9194 C CD . GLN C 1 319 ? -10.823 60.087 24.926 1.00 15.33 ? 352 GLN C CD 1 ATOM 9195 O OE1 . GLN C 1 319 ? -11.645 60.965 25.189 1.00 15.41 ? 352 GLN C OE1 1 ATOM 9196 N NE2 . GLN C 1 319 ? -10.476 59.771 23.666 1.00 14.18 ? 352 GLN C NE2 1 ATOM 9197 N N . TYR C 1 320 ? -10.683 56.555 24.149 1.00 15.04 ? 353 TYR C N 1 ATOM 9198 C CA . TYR C 1 320 ? -9.767 55.610 23.504 1.00 16.37 ? 353 TYR C CA 1 ATOM 9199 C C . TYR C 1 320 ? -8.715 56.449 22.907 1.00 16.40 ? 353 TYR C C 1 ATOM 9200 O O . TYR C 1 320 ? -8.919 57.675 22.725 1.00 15.28 ? 353 TYR C O 1 ATOM 9201 C CB . TYR C 1 320 ? -10.446 54.845 22.395 1.00 15.98 ? 353 TYR C CB 1 ATOM 9202 C CG . TYR C 1 320 ? -11.518 53.938 22.843 1.00 15.68 ? 353 TYR C CG 1 ATOM 9203 C CD1 . TYR C 1 320 ? -11.249 52.580 23.016 1.00 16.40 ? 353 TYR C CD1 1 ATOM 9204 C CD2 . TYR C 1 320 ? -12.812 54.392 23.045 1.00 15.67 ? 353 TYR C CD2 1 ATOM 9205 C CE1 . TYR C 1 320 ? -12.251 51.666 23.421 1.00 16.43 ? 353 TYR C CE1 1 ATOM 9206 C CE2 . TYR C 1 320 ? -13.837 53.496 23.423 1.00 16.58 ? 353 TYR C CE2 1 ATOM 9207 C CZ . TYR C 1 320 ? -13.548 52.123 23.622 1.00 16.46 ? 353 TYR C CZ 1 ATOM 9208 O OH . TYR C 1 320 ? -14.480 51.194 23.981 1.00 14.46 ? 353 TYR C OH 1 ATOM 9209 N N . TYR C 1 321 ? -7.605 55.814 22.575 1.00 16.71 ? 354 TYR C N 1 ATOM 9210 C CA . TYR C 1 321 ? -6.478 56.598 22.127 1.00 16.85 ? 354 TYR C CA 1 ATOM 9211 C C . TYR C 1 321 ? -5.513 55.770 21.412 1.00 17.40 ? 354 TYR C C 1 ATOM 9212 O O . TYR C 1 321 ? -5.479 54.528 21.558 1.00 19.51 ? 354 TYR C O 1 ATOM 9213 C CB . TYR C 1 321 ? -5.755 57.231 23.302 1.00 17.84 ? 354 TYR C CB 1 ATOM 9214 C CG . TYR C 1 321 ? -4.759 56.325 24.100 1.00 19.50 ? 354 TYR C CG 1 ATOM 9215 C CD1 . TYR C 1 321 ? -5.210 55.310 24.997 1.00 18.84 ? 354 TYR C CD1 1 ATOM 9216 C CD2 . TYR C 1 321 ? -3.377 56.522 23.996 1.00 18.96 ? 354 TYR C CD2 1 ATOM 9217 C CE1 . TYR C 1 321 ? -4.321 54.543 25.713 1.00 17.72 ? 354 TYR C CE1 1 ATOM 9218 C CE2 . TYR C 1 321 ? -2.497 55.767 24.740 1.00 18.76 ? 354 TYR C CE2 1 ATOM 9219 C CZ . TYR C 1 321 ? -2.972 54.782 25.580 1.00 18.06 ? 354 TYR C CZ 1 ATOM 9220 O OH . TYR C 1 321 ? -2.041 54.038 26.256 1.00 17.88 ? 354 TYR C OH 1 ATOM 9221 N N . LEU C 1 322 ? -4.668 56.473 20.674 1.00 17.74 ? 355 LEU C N 1 ATOM 9222 C CA . LEU C 1 322 ? -3.624 55.832 19.879 1.00 17.09 ? 355 LEU C CA 1 ATOM 9223 C C . LEU C 1 322 ? -2.302 56.322 20.502 1.00 17.89 ? 355 LEU C C 1 ATOM 9224 O O . LEU C 1 322 ? -2.061 57.559 20.614 1.00 15.07 ? 355 LEU C O 1 ATOM 9225 C CB . LEU C 1 322 ? -3.772 56.207 18.390 1.00 16.48 ? 355 LEU C CB 1 ATOM 9226 C CG . LEU C 1 322 ? -2.601 55.608 17.720 1.00 16.46 ? 355 LEU C CG 1 ATOM 9227 C CD1 . LEU C 1 322 ? -2.890 54.135 17.726 1.00 17.66 ? 355 LEU C CD1 1 ATOM 9228 C CD2 . LEU C 1 322 ? -2.401 56.106 16.331 1.00 17.68 ? 355 LEU C CD2 1 ATOM 9229 N N . ASN C 1 323 ? -1.491 55.369 20.992 1.00 18.78 ? 356 ASN C N 1 ATOM 9230 C CA . ASN C 1 323 ? -0.130 55.709 21.432 1.00 19.44 ? 356 ASN C CA 1 ATOM 9231 C C . ASN C 1 323 ? 0.714 55.907 20.200 1.00 19.90 ? 356 ASN C C 1 ATOM 9232 O O . ASN C 1 323 ? 1.247 54.940 19.620 1.00 18.89 ? 356 ASN C O 1 ATOM 9233 C CB . ASN C 1 323 ? 0.501 54.622 22.341 1.00 20.70 ? 356 ASN C CB 1 ATOM 9234 C CG . ASN C 1 323 ? 1.912 54.990 22.740 1.00 20.46 ? 356 ASN C CG 1 ATOM 9235 O OD1 . ASN C 1 323 ? 2.560 55.702 21.959 1.00 19.33 ? 356 ASN C OD1 1 ATOM 9236 N ND2 . ASN C 1 323 ? 2.381 54.588 23.970 1.00 19.77 ? 356 ASN C ND2 1 ATOM 9237 N N . LEU C 1 324 ? 0.799 57.174 19.798 1.00 21.94 ? 357 LEU C N 1 ATOM 9238 C CA . LEU C 1 324 ? 1.488 57.597 18.550 1.00 22.91 ? 357 LEU C CA 1 ATOM 9239 C C . LEU C 1 324 ? 2.882 57.047 18.414 1.00 22.77 ? 357 LEU C C 1 ATOM 9240 O O . LEU C 1 324 ? 3.231 56.488 17.380 1.00 28.13 ? 357 LEU C O 1 ATOM 9241 C CB . LEU C 1 324 ? 1.526 59.108 18.366 1.00 23.70 ? 357 LEU C CB 1 ATOM 9242 C CG . LEU C 1 324 ? 1.867 59.548 16.941 1.00 26.88 ? 357 LEU C CG 1 ATOM 9243 C CD1 . LEU C 1 324 ? 0.707 59.264 15.951 1.00 26.66 ? 357 LEU C CD1 1 ATOM 9244 C CD2 . LEU C 1 324 ? 2.217 61.049 16.951 1.00 29.19 ? 357 LEU C CD2 1 ATOM 9245 N N . THR C 1 325 ? 3.664 57.164 19.460 1.00 24.08 ? 358 THR C N 1 ATOM 9246 C CA . THR C 1 325 ? 5.003 56.591 19.449 1.00 24.96 ? 358 THR C CA 1 ATOM 9247 C C . THR C 1 325 ? 4.976 55.109 19.181 1.00 22.32 ? 358 THR C C 1 ATOM 9248 O O . THR C 1 325 ? 5.699 54.637 18.340 1.00 20.04 ? 358 THR C O 1 ATOM 9249 C CB . THR C 1 325 ? 5.748 56.902 20.744 1.00 24.80 ? 358 THR C CB 1 ATOM 9250 O OG1 . THR C 1 325 ? 6.030 58.291 20.728 1.00 23.43 ? 358 THR C OG1 1 ATOM 9251 C CG2 . THR C 1 325 ? 7.088 56.149 20.797 1.00 27.49 ? 358 THR C CG2 1 ATOM 9252 N N . GLU C 1 326 ? 4.105 54.403 19.878 1.00 22.71 ? 359 GLU C N 1 ATOM 9253 C CA . GLU C 1 326 ? 4.050 52.961 19.722 1.00 24.52 ? 359 GLU C CA 1 ATOM 9254 C C . GLU C 1 326 ? 3.650 52.630 18.270 1.00 23.20 ? 359 GLU C C 1 ATOM 9255 O O . GLU C 1 326 ? 4.246 51.762 17.646 1.00 23.00 ? 359 GLU C O 1 ATOM 9256 C CB . GLU C 1 326 ? 3.106 52.310 20.745 1.00 25.70 ? 359 GLU C CB 1 ATOM 9257 C CG . GLU C 1 326 ? 2.908 50.799 20.570 1.00 27.08 ? 359 GLU C CG 1 ATOM 9258 C CD . GLU C 1 326 ? 1.895 50.212 21.550 1.00 30.46 ? 359 GLU C CD 1 ATOM 9259 O OE1 . GLU C 1 326 ? 1.632 50.814 22.637 1.00 30.00 ? 359 GLU C OE1 1 ATOM 9260 O OE2 . GLU C 1 326 ? 1.339 49.131 21.242 1.00 35.63 -1 359 GLU C OE2 1 ATOM 9261 N N . ALA C 1 327 ? 2.678 53.369 17.748 1.00 21.65 ? 360 ALA C N 1 ATOM 9262 C CA . ALA C 1 327 ? 2.082 53.104 16.458 1.00 20.58 ? 360 ALA C CA 1 ATOM 9263 C C . ALA C 1 327 ? 3.147 53.181 15.361 1.00 21.75 ? 360 ALA C C 1 ATOM 9264 O O . ALA C 1 327 ? 3.286 52.258 14.522 1.00 18.43 ? 360 ALA C O 1 ATOM 9265 C CB . ALA C 1 327 ? 0.991 54.124 16.176 1.00 19.18 ? 360 ALA C CB 1 ATOM 9266 N N . ASN C 1 328 ? 3.878 54.303 15.369 1.00 22.08 ? 361 ASN C N 1 ATOM 9267 C CA . ASN C 1 328 ? 4.939 54.506 14.403 1.00 21.87 ? 361 ASN C CA 1 ATOM 9268 C C . ASN C 1 328 ? 6.108 53.566 14.680 1.00 24.27 ? 361 ASN C C 1 ATOM 9269 O O . ASN C 1 328 ? 6.755 53.141 13.707 1.00 26.31 ? 361 ASN C O 1 ATOM 9270 C CB . ASN C 1 328 ? 5.464 55.944 14.404 1.00 19.57 ? 361 ASN C CB 1 ATOM 9271 C CG . ASN C 1 328 ? 4.489 56.908 13.848 1.00 18.34 ? 361 ASN C CG 1 ATOM 9272 O OD1 . ASN C 1 328 ? 3.674 56.604 12.948 1.00 16.02 ? 361 ASN C OD1 1 ATOM 9273 N ND2 . ASN C 1 328 ? 4.574 58.101 14.355 1.00 18.11 ? 361 ASN C ND2 1 ATOM 9274 N N . LEU C 1 329 ? 6.432 53.251 15.944 1.00 23.95 ? 362 LEU C N 1 ATOM 9275 C CA . LEU C 1 329 ? 7.511 52.273 16.148 1.00 25.81 ? 362 LEU C CA 1 ATOM 9276 C C . LEU C 1 329 ? 7.187 50.944 15.427 1.00 27.37 ? 362 LEU C C 1 ATOM 9277 O O . LEU C 1 329 ? 8.002 50.419 14.670 1.00 25.29 ? 362 LEU C O 1 ATOM 9278 C CB . LEU C 1 329 ? 7.844 52.075 17.614 1.00 27.11 ? 362 LEU C CB 1 ATOM 9279 C CG . LEU C 1 329 ? 8.861 53.167 18.030 1.00 30.17 ? 362 LEU C CG 1 ATOM 9280 C CD1 . LEU C 1 329 ? 8.969 53.346 19.549 1.00 29.47 ? 362 LEU C CD1 1 ATOM 9281 C CD2 . LEU C 1 329 ? 10.230 52.881 17.406 1.00 31.65 ? 362 LEU C CD2 1 ATOM 9282 N N . LYS C 1 330 ? 5.961 50.468 15.582 1.00 29.70 ? 363 LYS C N 1 ATOM 9283 C CA . LYS C 1 330 ? 5.550 49.152 15.059 1.00 32.08 ? 363 LYS C CA 1 ATOM 9284 C C . LYS C 1 330 ? 4.908 49.257 13.686 1.00 31.09 ? 363 LYS C C 1 ATOM 9285 O O . LYS C 1 330 ? 4.595 48.248 13.065 1.00 31.14 ? 363 LYS C O 1 ATOM 9286 C CB . LYS C 1 330 ? 4.549 48.488 16.040 1.00 32.34 ? 363 LYS C CB 1 ATOM 9287 C CG . LYS C 1 330 ? 5.201 47.968 17.300 1.00 31.38 ? 363 LYS C CG 1 ATOM 9288 C CD . LYS C 1 330 ? 4.262 47.979 18.480 1.00 33.75 ? 363 LYS C CD 1 ATOM 9289 C CE . LYS C 1 330 ? 3.265 46.839 18.467 1.00 37.23 ? 363 LYS C CE 1 ATOM 9290 N NZ . LYS C 1 330 ? 2.658 46.732 19.822 1.00 38.80 1 363 LYS C NZ 1 ATOM 9291 N N . GLY C 1 331 ? 4.681 50.478 13.224 1.00 31.09 ? 364 GLY C N 1 ATOM 9292 C CA . GLY C 1 331 ? 3.831 50.697 12.055 1.00 31.27 ? 364 GLY C CA 1 ATOM 9293 C C . GLY C 1 331 ? 2.552 49.887 12.220 1.00 31.01 ? 364 GLY C C 1 ATOM 9294 O O . GLY C 1 331 ? 2.094 49.243 11.288 1.00 30.38 ? 364 GLY C O 1 ATOM 9295 N N . GLU C 1 332 ? 1.982 49.880 13.418 1.00 31.06 ? 365 GLU C N 1 ATOM 9296 C CA . GLU C 1 332 ? 0.689 49.234 13.596 1.00 31.78 ? 365 GLU C CA 1 ATOM 9297 C C . GLU C 1 332 ? -0.268 50.182 14.308 1.00 28.84 ? 365 GLU C C 1 ATOM 9298 O O . GLU C 1 332 ? 0.095 50.924 15.208 1.00 28.01 ? 365 GLU C O 1 ATOM 9299 C CB . GLU C 1 332 ? 0.766 47.877 14.357 1.00 33.46 ? 365 GLU C CB 1 ATOM 9300 C CG . GLU C 1 332 ? 1.523 46.732 13.687 1.00 37.01 ? 365 GLU C CG 1 ATOM 9301 C CD . GLU C 1 332 ? 0.868 46.159 12.402 1.00 41.06 ? 365 GLU C CD 1 ATOM 9302 O OE1 . GLU C 1 332 ? -0.376 46.326 12.224 1.00 41.22 ? 365 GLU C OE1 1 ATOM 9303 O OE2 . GLU C 1 332 ? 1.601 45.510 11.575 1.00 38.51 -1 365 GLU C OE2 1 ATOM 9304 N N . SER C 1 333 ? -1.519 50.033 13.916 1.00 28.95 ? 366 SER C N 1 ATOM 9305 C CA . SER C 1 333 ? -2.650 50.870 14.262 1.00 27.43 ? 366 SER C CA 1 ATOM 9306 C C . SER C 1 333 ? -3.259 50.509 15.628 1.00 26.96 ? 366 SER C C 1 ATOM 9307 O O . SER C 1 333 ? -4.443 50.266 15.692 1.00 27.92 ? 366 SER C O 1 ATOM 9308 C CB . SER C 1 333 ? -3.700 50.593 13.162 1.00 28.21 ? 366 SER C CB 1 ATOM 9309 O OG . SER C 1 333 ? -4.507 51.687 12.922 1.00 27.02 ? 366 SER C OG 1 ATOM 9310 N N . ILE C 1 334 ? -2.502 50.538 16.724 1.00 26.94 ? 367 ILE C N 1 ATOM 9311 C CA . ILE C 1 334 ? -3.036 50.032 17.974 1.00 28.73 ? 367 ILE C CA 1 ATOM 9312 C C . ILE C 1 334 ? -3.882 51.040 18.780 1.00 27.60 ? 367 ILE C C 1 ATOM 9313 O O . ILE C 1 334 ? -3.355 51.727 19.683 1.00 30.99 ? 367 ILE C O 1 ATOM 9314 C CB . ILE C 1 334 ? -1.948 49.458 18.931 1.00 32.78 ? 367 ILE C CB 1 ATOM 9315 C CG1 . ILE C 1 334 ? -0.665 49.028 18.189 1.00 34.89 ? 367 ILE C CG1 1 ATOM 9316 C CG2 . ILE C 1 334 ? -2.534 48.330 19.801 1.00 31.02 ? 367 ILE C CG2 1 ATOM 9317 C CD1 . ILE C 1 334 ? -0.796 47.756 17.404 1.00 34.56 ? 367 ILE C CD1 1 ATOM 9318 N N . TRP C 1 335 ? -5.188 51.086 18.510 1.00 24.42 ? 368 TRP C N 1 ATOM 9319 C CA . TRP C 1 335 ? -6.157 51.841 19.365 1.00 23.74 ? 368 TRP C CA 1 ATOM 9320 C C . TRP C 1 335 ? -6.354 51.168 20.723 1.00 23.93 ? 368 TRP C C 1 ATOM 9321 O O . TRP C 1 335 ? -6.453 49.920 20.824 1.00 23.85 ? 368 TRP C O 1 ATOM 9322 C CB . TRP C 1 335 ? -7.494 52.085 18.636 1.00 22.94 ? 368 TRP C CB 1 ATOM 9323 C CG . TRP C 1 335 ? -7.206 52.962 17.477 1.00 22.43 ? 368 TRP C CG 1 ATOM 9324 C CD1 . TRP C 1 335 ? -6.698 52.576 16.270 1.00 24.29 ? 368 TRP C CD1 1 ATOM 9325 C CD2 . TRP C 1 335 ? -7.278 54.393 17.451 1.00 21.06 ? 368 TRP C CD2 1 ATOM 9326 N NE1 . TRP C 1 335 ? -6.468 53.716 15.462 1.00 23.95 ? 368 TRP C NE1 1 ATOM 9327 C CE2 . TRP C 1 335 ? -6.834 54.828 16.169 1.00 21.49 ? 368 TRP C CE2 1 ATOM 9328 C CE3 . TRP C 1 335 ? -7.670 55.363 18.395 1.00 23.33 ? 368 TRP C CE3 1 ATOM 9329 C CZ2 . TRP C 1 335 ? -6.795 56.166 15.798 1.00 19.97 ? 368 TRP C CZ2 1 ATOM 9330 C CZ3 . TRP C 1 335 ? -7.628 56.733 18.005 1.00 22.99 ? 368 TRP C CZ3 1 ATOM 9331 C CH2 . TRP C 1 335 ? -7.211 57.095 16.701 1.00 20.51 ? 368 TRP C CH2 1 ATOM 9332 N N . LYS C 1 336 ? -6.330 51.984 21.778 1.00 22.26 ? 369 LYS C N 1 ATOM 9333 C CA . LYS C 1 336 ? -6.455 51.469 23.123 1.00 19.76 ? 369 LYS C CA 1 ATOM 9334 C C . LYS C 1 336 ? -7.401 52.261 23.979 1.00 19.13 ? 369 LYS C C 1 ATOM 9335 O O . LYS C 1 336 ? -7.555 53.547 23.829 1.00 16.47 ? 369 LYS C O 1 ATOM 9336 C CB . LYS C 1 336 ? -5.115 51.508 23.821 1.00 21.25 ? 369 LYS C CB 1 ATOM 9337 C CG . LYS C 1 336 ? -4.060 50.618 23.223 1.00 22.74 ? 369 LYS C CG 1 ATOM 9338 C CD . LYS C 1 336 ? -2.776 50.760 24.026 1.00 23.13 ? 369 LYS C CD 1 ATOM 9339 C CE . LYS C 1 336 ? -1.627 50.037 23.353 1.00 23.63 ? 369 LYS C CE 1 ATOM 9340 N NZ . LYS C 1 336 ? -0.418 50.048 24.211 1.00 24.03 1 369 LYS C NZ 1 ATOM 9341 N N . LEU C 1 337 ? -7.962 51.499 24.929 1.00 17.64 ? 370 LEU C N 1 ATOM 9342 C CA . LEU C 1 337 ? -8.757 52.042 26.004 1.00 17.63 ? 370 LEU C CA 1 ATOM 9343 C C . LEU C 1 337 ? -7.879 52.847 26.988 1.00 16.41 ? 370 LEU C C 1 ATOM 9344 O O . LEU C 1 337 ? -7.054 52.347 27.675 1.00 16.38 ? 370 LEU C O 1 ATOM 9345 C CB . LEU C 1 337 ? -9.520 50.920 26.731 1.00 19.55 ? 370 LEU C CB 1 ATOM 9346 C CG . LEU C 1 337 ? -10.450 51.407 27.875 1.00 20.44 ? 370 LEU C CG 1 ATOM 9347 C CD1 . LEU C 1 337 ? -11.459 52.402 27.307 1.00 19.51 ? 370 LEU C CD1 1 ATOM 9348 C CD2 . LEU C 1 337 ? -11.130 50.259 28.625 1.00 21.02 ? 370 LEU C CD2 1 ATOM 9349 N N . GLU C 1 338 ? -8.108 54.131 27.068 1.00 16.40 ? 371 GLU C N 1 ATOM 9350 C CA . GLU C 1 338 ? -7.416 54.983 28.033 1.00 15.53 ? 371 GLU C CA 1 ATOM 9351 C C . GLU C 1 338 ? -8.093 54.899 29.409 1.00 13.88 ? 371 GLU C C 1 ATOM 9352 O O . GLU C 1 338 ? -7.437 54.653 30.365 1.00 11.67 ? 371 GLU C O 1 ATOM 9353 C CB . GLU C 1 338 ? -7.392 56.444 27.508 1.00 15.97 ? 371 GLU C CB 1 ATOM 9354 C CG . GLU C 1 338 ? -6.349 57.306 28.210 1.00 17.24 ? 371 GLU C CG 1 ATOM 9355 C CD . GLU C 1 338 ? -6.532 58.835 28.020 1.00 18.31 ? 371 GLU C CD 1 ATOM 9356 O OE1 . GLU C 1 338 ? -7.612 59.284 27.526 1.00 16.56 ? 371 GLU C OE1 1 ATOM 9357 O OE2 . GLU C 1 338 ? -5.540 59.575 28.350 1.00 18.34 -1 371 GLU C OE2 1 ATOM 9358 N N . TYR C 1 339 ? -9.393 55.219 29.479 1.00 14.15 ? 372 TYR C N 1 ATOM 9359 C CA . TYR C 1 339 ? -10.167 55.052 30.708 1.00 15.46 ? 372 TYR C CA 1 ATOM 9360 C C . TYR C 1 339 ? -11.663 54.877 30.430 1.00 14.57 ? 372 TYR C C 1 ATOM 9361 O O . TYR C 1 339 ? -12.135 55.229 29.378 1.00 13.29 ? 372 TYR C O 1 ATOM 9362 C CB . TYR C 1 339 ? -9.940 56.208 31.742 1.00 15.62 ? 372 TYR C CB 1 ATOM 9363 C CG . TYR C 1 339 ? -10.460 57.543 31.267 1.00 17.66 ? 372 TYR C CG 1 ATOM 9364 C CD1 . TYR C 1 339 ? -11.809 57.924 31.426 1.00 17.82 ? 372 TYR C CD1 1 ATOM 9365 C CD2 . TYR C 1 339 ? -9.597 58.443 30.599 1.00 19.06 ? 372 TYR C CD2 1 ATOM 9366 C CE1 . TYR C 1 339 ? -12.260 59.192 30.962 1.00 18.61 ? 372 TYR C CE1 1 ATOM 9367 C CE2 . TYR C 1 339 ? -10.050 59.711 30.144 1.00 19.91 ? 372 TYR C CE2 1 ATOM 9368 C CZ . TYR C 1 339 ? -11.364 60.073 30.311 1.00 18.16 ? 372 TYR C CZ 1 ATOM 9369 O OH . TYR C 1 339 ? -11.700 61.271 29.834 1.00 14.96 ? 372 TYR C OH 1 ATOM 9370 N N . ILE C 1 340 ? -12.311 54.208 31.370 1.00 15.43 ? 373 ILE C N 1 ATOM 9371 C CA . ILE C 1 340 ? -13.722 54.236 31.611 1.00 18.72 ? 373 ILE C CA 1 ATOM 9372 C C . ILE C 1 340 ? -13.905 55.239 32.819 1.00 20.02 ? 373 ILE C C 1 ATOM 9373 O O . ILE C 1 340 ? -13.437 54.999 33.916 1.00 21.30 ? 373 ILE C O 1 ATOM 9374 C CB . ILE C 1 340 ? -14.202 52.832 32.052 1.00 21.21 ? 373 ILE C CB 1 ATOM 9375 C CG1 . ILE C 1 340 ? -13.782 51.733 31.037 1.00 22.73 ? 373 ILE C CG1 1 ATOM 9376 C CG2 . ILE C 1 340 ? -15.715 52.824 32.322 1.00 22.12 ? 373 ILE C CG2 1 ATOM 9377 C CD1 . ILE C 1 340 ? -13.998 50.281 31.525 1.00 21.71 ? 373 ILE C CD1 1 ATOM 9378 N N . LEU C 1 341 ? -14.622 56.321 32.628 1.00 20.68 ? 374 LEU C N 1 ATOM 9379 C CA . LEU C 1 341 ? -14.609 57.432 33.524 1.00 22.04 ? 374 LEU C CA 1 ATOM 9380 C C . LEU C 1 341 ? -15.180 57.154 34.916 1.00 22.44 ? 374 LEU C C 1 ATOM 9381 O O . LEU C 1 341 ? -14.629 57.697 35.905 1.00 23.20 ? 374 LEU C O 1 ATOM 9382 C CB . LEU C 1 341 ? -15.419 58.544 32.857 1.00 25.94 ? 374 LEU C CB 1 ATOM 9383 C CG . LEU C 1 341 ? -15.446 59.928 33.524 1.00 29.48 ? 374 LEU C CG 1 ATOM 9384 C CD1 . LEU C 1 341 ? -15.700 61.034 32.511 1.00 29.45 ? 374 LEU C CD1 1 ATOM 9385 C CD2 . LEU C 1 341 ? -16.522 60.008 34.609 1.00 30.16 ? 374 LEU C CD2 1 ATOM 9386 N N . THR C 1 342 ? -16.272 56.379 35.017 1.00 20.45 ? 375 THR C N 1 ATOM 9387 C CA . THR C 1 342 ? -16.797 55.943 36.357 1.00 22.19 ? 375 THR C CA 1 ATOM 9388 C C . THR C 1 342 ? -15.838 55.011 37.104 1.00 25.11 ? 375 THR C C 1 ATOM 9389 O O . THR C 1 342 ? -15.791 55.038 38.343 1.00 27.34 ? 375 THR C O 1 ATOM 9390 C CB . THR C 1 342 ? -18.235 55.275 36.405 1.00 20.91 ? 375 THR C CB 1 ATOM 9391 O OG1 . THR C 1 342 ? -18.345 54.116 35.571 1.00 18.85 ? 375 THR C OG1 1 ATOM 9392 C CG2 . THR C 1 342 ? -19.326 56.245 36.041 1.00 20.48 ? 375 THR C CG2 1 ATOM 9393 N N . GLN C 1 343 ? -15.069 54.224 36.365 1.00 27.16 ? 376 GLN C N 1 ATOM 9394 C CA . GLN C 1 343 ? -14.062 53.350 36.960 1.00 30.54 ? 376 GLN C CA 1 ATOM 9395 C C . GLN C 1 343 ? -12.820 54.090 37.456 1.00 26.71 ? 376 GLN C C 1 ATOM 9396 O O . GLN C 1 343 ? -12.423 53.891 38.614 1.00 28.79 ? 376 GLN C O 1 ATOM 9397 C CB . GLN C 1 343 ? -13.637 52.211 36.000 1.00 37.26 ? 376 GLN C CB 1 ATOM 9398 C CG . GLN C 1 343 ? -14.749 51.218 35.636 1.00 44.20 ? 376 GLN C CG 1 ATOM 9399 C CD . GLN C 1 343 ? -15.313 50.465 36.848 1.00 49.96 ? 376 GLN C CD 1 ATOM 9400 O OE1 . GLN C 1 343 ? -14.603 49.686 37.505 1.00 56.06 ? 376 GLN C OE1 1 ATOM 9401 N NE2 . GLN C 1 343 ? -16.596 50.705 37.159 1.00 50.39 ? 376 GLN C NE2 1 ATOM 9402 N N . THR C 1 344 ? -12.176 54.914 36.633 1.00 23.44 ? 377 THR C N 1 ATOM 9403 C CA . THR C 1 344 ? -10.929 55.540 37.134 1.00 23.49 ? 377 THR C CA 1 ATOM 9404 C C . THR C 1 344 ? -11.199 56.491 38.278 1.00 21.99 ? 377 THR C C 1 ATOM 9405 O O . THR C 1 344 ? -10.353 56.641 39.142 1.00 22.63 ? 377 THR C O 1 ATOM 9406 C CB . THR C 1 344 ? -10.088 56.365 36.110 1.00 23.30 ? 377 THR C CB 1 ATOM 9407 O OG1 . THR C 1 344 ? -10.927 56.942 35.105 1.00 23.64 ? 377 THR C OG1 1 ATOM 9408 C CG2 . THR C 1 344 ? -8.996 55.583 35.524 1.00 22.85 ? 377 THR C CG2 1 ATOM 9409 N N . TYR C 1 345 ? -12.341 57.171 38.247 1.00 21.38 ? 378 TYR C N 1 ATOM 9410 C CA . TYR C 1 345 ? -12.612 58.199 39.219 1.00 22.21 ? 378 TYR C CA 1 ATOM 9411 C C . TYR C 1 345 ? -13.574 57.772 40.330 1.00 25.15 ? 378 TYR C C 1 ATOM 9412 O O . TYR C 1 345 ? -13.776 58.534 41.254 1.00 24.10 ? 378 TYR C O 1 ATOM 9413 C CB . TYR C 1 345 ? -13.158 59.426 38.514 1.00 21.45 ? 378 TYR C CB 1 ATOM 9414 C CG . TYR C 1 345 ? -12.154 60.179 37.665 1.00 20.18 ? 378 TYR C CG 1 ATOM 9415 C CD1 . TYR C 1 345 ? -10.988 60.728 38.222 1.00 19.82 ? 378 TYR C CD1 1 ATOM 9416 C CD2 . TYR C 1 345 ? -12.379 60.363 36.284 1.00 18.84 ? 378 TYR C CD2 1 ATOM 9417 C CE1 . TYR C 1 345 ? -10.073 61.454 37.406 1.00 19.45 ? 378 TYR C CE1 1 ATOM 9418 C CE2 . TYR C 1 345 ? -11.485 61.050 35.482 1.00 17.57 ? 378 TYR C CE2 1 ATOM 9419 C CZ . TYR C 1 345 ? -10.336 61.601 36.015 1.00 17.87 ? 378 TYR C CZ 1 ATOM 9420 O OH . TYR C 1 345 ? -9.489 62.286 35.179 1.00 15.29 ? 378 TYR C OH 1 ATOM 9421 N N . ASP C 1 346 ? -14.172 56.576 40.238 1.00 30.00 ? 379 ASP C N 1 ATOM 9422 C CA . ASP C 1 346 ? -15.095 56.077 41.282 1.00 35.71 ? 379 ASP C CA 1 ATOM 9423 C C . ASP C 1 346 ? -16.250 57.048 41.580 1.00 32.14 ? 379 ASP C C 1 ATOM 9424 O O . ASP C 1 346 ? -16.398 57.572 42.664 1.00 33.83 ? 379 ASP C O 1 ATOM 9425 C CB . ASP C 1 346 ? -14.312 55.712 42.565 1.00 41.18 ? 379 ASP C CB 1 ATOM 9426 C CG . ASP C 1 346 ? -13.156 54.763 42.273 1.00 50.27 ? 379 ASP C CG 1 ATOM 9427 O OD1 . ASP C 1 346 ? -13.401 53.674 41.691 1.00 57.53 ? 379 ASP C OD1 1 ATOM 9428 O OD2 . ASP C 1 346 ? -11.994 55.126 42.562 1.00 63.10 -1 379 ASP C OD2 1 ATOM 9429 N N . ILE C 1 347 ? -17.059 57.284 40.574 1.00 31.40 ? 380 ILE C N 1 ATOM 9430 C CA . ILE C 1 347 ? -18.259 58.083 40.711 1.00 28.56 ? 380 ILE C CA 1 ATOM 9431 C C . ILE C 1 347 ? -19.369 57.290 40.047 1.00 29.28 ? 380 ILE C C 1 ATOM 9432 O O . ILE C 1 347 ? -19.120 56.346 39.320 1.00 28.37 ? 380 ILE C O 1 ATOM 9433 C CB . ILE C 1 347 ? -18.114 59.473 40.082 1.00 29.38 ? 380 ILE C CB 1 ATOM 9434 C CG1 . ILE C 1 347 ? -17.619 59.389 38.628 1.00 29.30 ? 380 ILE C CG1 1 ATOM 9435 C CG2 . ILE C 1 347 ? -17.203 60.344 40.950 1.00 30.44 ? 380 ILE C CG2 1 ATOM 9436 C CD1 . ILE C 1 347 ? -17.650 60.732 37.946 1.00 31.94 ? 380 ILE C CD1 1 ATOM 9437 N N . GLU C 1 348 ? -20.601 57.650 40.341 1.00 34.33 ? 381 GLU C N 1 ATOM 9438 C CA . GLU C 1 348 ? -21.743 56.855 39.914 1.00 37.75 ? 381 GLU C CA 1 ATOM 9439 C C . GLU C 1 348 ? -21.952 56.971 38.411 1.00 33.05 ? 381 GLU C C 1 ATOM 9440 O O . GLU C 1 348 ? -22.214 55.952 37.753 1.00 31.55 ? 381 GLU C O 1 ATOM 9441 C CB . GLU C 1 348 ? -23.032 57.266 40.664 1.00 45.04 ? 381 GLU C CB 1 ATOM 9442 C CG . GLU C 1 348 ? -22.959 57.193 42.186 1.00 53.74 ? 381 GLU C CG 1 ATOM 9443 C CD . GLU C 1 348 ? -22.357 55.880 42.706 1.00 63.98 ? 381 GLU C CD 1 ATOM 9444 O OE1 . GLU C 1 348 ? -22.852 54.786 42.334 1.00 67.69 ? 381 GLU C OE1 1 ATOM 9445 O OE2 . GLU C 1 348 ? -21.385 55.935 43.499 1.00 73.83 -1 381 GLU C OE2 1 ATOM 9446 N N . ASP C 1 349 ? -21.812 58.203 37.887 1.00 29.44 ? 382 ASP C N 1 ATOM 9447 C CA . ASP C 1 349 ? -22.260 58.560 36.522 1.00 27.63 ? 382 ASP C CA 1 ATOM 9448 C C . ASP C 1 349 ? -21.735 59.958 36.109 1.00 24.25 ? 382 ASP C C 1 ATOM 9449 O O . ASP C 1 349 ? -20.934 60.545 36.804 1.00 24.76 ? 382 ASP C O 1 ATOM 9450 C CB . ASP C 1 349 ? -23.808 58.537 36.476 1.00 28.00 ? 382 ASP C CB 1 ATOM 9451 C CG . ASP C 1 349 ? -24.434 59.500 37.497 1.00 28.57 ? 382 ASP C CG 1 ATOM 9452 O OD1 . ASP C 1 349 ? -23.807 60.530 37.855 1.00 28.55 ? 382 ASP C OD1 1 ATOM 9453 O OD2 . ASP C 1 349 ? -25.559 59.234 37.957 1.00 32.89 -1 382 ASP C OD2 1 ATOM 9454 N N . LEU C 1 350 ? -22.255 60.507 35.019 1.00 22.56 ? 383 LEU C N 1 ATOM 9455 C CA . LEU C 1 350 ? -21.830 61.798 34.492 1.00 22.12 ? 383 LEU C CA 1 ATOM 9456 C C . LEU C 1 350 ? -22.750 62.966 34.833 1.00 22.59 ? 383 LEU C C 1 ATOM 9457 O O . LEU C 1 350 ? -22.592 64.087 34.264 1.00 17.89 ? 383 LEU C O 1 ATOM 9458 C CB . LEU C 1 350 ? -21.656 61.694 33.002 1.00 21.95 ? 383 LEU C CB 1 ATOM 9459 C CG . LEU C 1 350 ? -20.344 60.987 32.582 1.00 23.53 ? 383 LEU C CG 1 ATOM 9460 C CD1 . LEU C 1 350 ? -19.891 59.753 33.396 1.00 23.38 ? 383 LEU C CD1 1 ATOM 9461 C CD2 . LEU C 1 350 ? -20.452 60.662 31.094 1.00 23.39 ? 383 LEU C CD2 1 ATOM 9462 N N . GLN C 1 351 ? -23.634 62.731 35.827 1.00 24.07 ? 384 GLN C N 1 ATOM 9463 C CA . GLN C 1 351 ? -24.553 63.781 36.312 1.00 26.87 ? 384 GLN C CA 1 ATOM 9464 C C . GLN C 1 351 ? -23.738 64.904 36.918 1.00 26.70 ? 384 GLN C C 1 ATOM 9465 O O . GLN C 1 351 ? -22.654 64.645 37.497 1.00 24.95 ? 384 GLN C O 1 ATOM 9466 C CB . GLN C 1 351 ? -25.480 63.364 37.451 1.00 29.42 ? 384 GLN C CB 1 ATOM 9467 C CG . GLN C 1 351 ? -26.194 62.065 37.311 1.00 35.17 ? 384 GLN C CG 1 ATOM 9468 C CD . GLN C 1 351 ? -27.634 62.213 36.970 1.00 36.12 ? 384 GLN C CD 1 ATOM 9469 O OE1 . GLN C 1 351 ? -27.972 62.810 35.961 1.00 39.25 ? 384 GLN C OE1 1 ATOM 9470 N NE2 . GLN C 1 351 ? -28.491 61.609 37.774 1.00 37.07 ? 384 GLN C NE2 1 ATOM 9471 N N . PRO C 1 352 ? -24.297 66.130 36.861 1.00 24.95 ? 385 PRO C N 1 ATOM 9472 C CA . PRO C 1 352 ? -23.657 67.298 37.422 1.00 25.80 ? 385 PRO C CA 1 ATOM 9473 C C . PRO C 1 352 ? -23.093 67.100 38.814 1.00 25.36 ? 385 PRO C C 1 ATOM 9474 O O . PRO C 1 352 ? -21.913 67.371 39.026 1.00 24.31 ? 385 PRO C O 1 ATOM 9475 C CB . PRO C 1 352 ? -24.782 68.349 37.389 1.00 26.32 ? 385 PRO C CB 1 ATOM 9476 C CG . PRO C 1 352 ? -25.541 68.010 36.136 1.00 24.55 ? 385 PRO C CG 1 ATOM 9477 C CD . PRO C 1 352 ? -25.411 66.511 35.965 1.00 23.72 ? 385 PRO C CD 1 ATOM 9478 N N . GLU C 1 353 ? -23.931 66.597 39.714 1.00 27.42 ? 386 GLU C N 1 ATOM 9479 C CA . GLU C 1 353 ? -23.594 66.382 41.139 1.00 28.11 ? 386 GLU C CA 1 ATOM 9480 C C . GLU C 1 353 ? -22.383 65.469 41.278 1.00 26.00 ? 386 GLU C C 1 ATOM 9481 O O . GLU C 1 353 ? -21.479 65.772 42.069 1.00 24.56 ? 386 GLU C O 1 ATOM 9482 C CB . GLU C 1 353 ? -24.777 65.765 41.900 1.00 32.77 ? 386 GLU C CB 1 ATOM 9483 C CG . GLU C 1 353 ? -26.179 66.331 41.551 1.00 37.85 ? 386 GLU C CG 1 ATOM 9484 C CD . GLU C 1 353 ? -26.758 65.796 40.223 1.00 38.93 ? 386 GLU C CD 1 ATOM 9485 O OE1 . GLU C 1 353 ? -26.545 64.598 39.930 1.00 39.66 ? 386 GLU C OE1 1 ATOM 9486 O OE2 . GLU C 1 353 ? -27.413 66.576 39.473 1.00 41.50 -1 386 GLU C OE2 1 ATOM 9487 N N . SER C 1 354 ? -22.342 64.382 40.490 1.00 23.79 ? 387 SER C N 1 ATOM 9488 C CA . SER C 1 354 ? -21.145 63.516 40.411 1.00 23.09 ? 387 SER C CA 1 ATOM 9489 C C . SER C 1 354 ? -19.865 64.207 39.891 1.00 22.31 ? 387 SER C C 1 ATOM 9490 O O . SER C 1 354 ? -18.819 64.037 40.469 1.00 23.58 ? 387 SER C O 1 ATOM 9491 C CB . SER C 1 354 ? -21.394 62.319 39.504 1.00 23.03 ? 387 SER C CB 1 ATOM 9492 O OG . SER C 1 354 ? -22.538 61.647 39.872 1.00 22.74 ? 387 SER C OG 1 ATOM 9493 N N . LEU C 1 355 ? -19.929 64.924 38.777 1.00 22.61 ? 388 LEU C N 1 ATOM 9494 C CA . LEU C 1 355 ? -18.736 65.620 38.264 1.00 25.34 ? 388 LEU C CA 1 ATOM 9495 C C . LEU C 1 355 ? -18.285 66.664 39.297 1.00 26.22 ? 388 LEU C C 1 ATOM 9496 O O . LEU C 1 355 ? -17.054 66.806 39.542 1.00 25.25 ? 388 LEU C O 1 ATOM 9497 C CB . LEU C 1 355 ? -18.949 66.321 36.907 1.00 25.01 ? 388 LEU C CB 1 ATOM 9498 C CG . LEU C 1 355 ? -19.326 65.469 35.715 1.00 27.51 ? 388 LEU C CG 1 ATOM 9499 C CD1 . LEU C 1 355 ? -19.230 66.291 34.427 1.00 31.76 ? 388 LEU C CD1 1 ATOM 9500 C CD2 . LEU C 1 355 ? -18.450 64.237 35.645 1.00 27.75 ? 388 LEU C CD2 1 ATOM 9501 N N . TYR C 1 356 ? -19.264 67.359 39.903 1.00 24.71 ? 389 TYR C N 1 ATOM 9502 C CA . TYR C 1 356 ? -18.981 68.396 40.891 1.00 27.17 ? 389 TYR C CA 1 ATOM 9503 C C . TYR C 1 356 ? -18.180 67.848 42.093 1.00 23.21 ? 389 TYR C C 1 ATOM 9504 O O . TYR C 1 356 ? -17.175 68.438 42.519 1.00 18.07 ? 389 TYR C O 1 ATOM 9505 C CB . TYR C 1 356 ? -20.269 69.054 41.352 1.00 31.91 ? 389 TYR C CB 1 ATOM 9506 C CG . TYR C 1 356 ? -20.026 70.248 42.214 1.00 37.65 ? 389 TYR C CG 1 ATOM 9507 C CD1 . TYR C 1 356 ? -19.503 71.431 41.675 1.00 44.50 ? 389 TYR C CD1 1 ATOM 9508 C CD2 . TYR C 1 356 ? -20.318 70.204 43.569 1.00 44.20 ? 389 TYR C CD2 1 ATOM 9509 C CE1 . TYR C 1 356 ? -19.282 72.553 42.471 1.00 49.98 ? 389 TYR C CE1 1 ATOM 9510 C CE2 . TYR C 1 356 ? -20.098 71.310 44.383 1.00 53.80 ? 389 TYR C CE2 1 ATOM 9511 C CZ . TYR C 1 356 ? -19.583 72.481 43.835 1.00 55.33 ? 389 TYR C CZ 1 ATOM 9512 O OH . TYR C 1 356 ? -19.378 73.560 44.669 1.00 68.47 ? 389 TYR C OH 1 ATOM 9513 N N . GLY C 1 357 ? -18.633 66.691 42.573 1.00 21.49 ? 390 GLY C N 1 ATOM 9514 C CA . GLY C 1 357 ? -17.902 65.871 43.517 1.00 20.72 ? 390 GLY C CA 1 ATOM 9515 C C . GLY C 1 357 ? -16.494 65.509 43.089 1.00 21.35 ? 390 GLY C C 1 ATOM 9516 O O . GLY C 1 357 ? -15.541 65.674 43.890 1.00 21.06 ? 390 GLY C O 1 ATOM 9517 N N . LEU C 1 358 ? -16.324 64.997 41.860 1.00 21.22 ? 391 LEU C N 1 ATOM 9518 C CA . LEU C 1 358 ? -14.945 64.696 41.392 1.00 22.20 ? 391 LEU C CA 1 ATOM 9519 C C . LEU C 1 358 ? -14.042 65.994 41.446 1.00 21.93 ? 391 LEU C C 1 ATOM 9520 O O . LEU C 1 358 ? -12.904 65.979 41.945 1.00 19.10 ? 391 LEU C O 1 ATOM 9521 C CB . LEU C 1 358 ? -14.951 64.049 39.996 1.00 22.52 ? 391 LEU C CB 1 ATOM 9522 C CG . LEU C 1 358 ? -13.597 63.659 39.374 1.00 21.41 ? 391 LEU C CG 1 ATOM 9523 C CD1 . LEU C 1 358 ? -12.828 62.692 40.297 1.00 21.59 ? 391 LEU C CD1 1 ATOM 9524 C CD2 . LEU C 1 358 ? -13.823 63.058 38.018 1.00 19.67 ? 391 LEU C CD2 1 ATOM 9525 N N . ALA C 1 359 ? -14.602 67.130 41.004 1.00 21.81 ? 392 ALA C N 1 ATOM 9526 C CA . ALA C 1 359 ? -13.870 68.404 41.005 1.00 21.96 ? 392 ALA C CA 1 ATOM 9527 C C . ALA C 1 359 ? -13.403 68.855 42.408 1.00 19.89 ? 392 ALA C C 1 ATOM 9528 O O . ALA C 1 359 ? -12.286 69.332 42.600 1.00 17.24 ? 392 ALA C O 1 ATOM 9529 C CB . ALA C 1 359 ? -14.687 69.468 40.288 1.00 22.35 ? 392 ALA C CB 1 ATOM 9530 N N . LYS C 1 360 ? -14.241 68.615 43.395 1.00 22.80 ? 393 LYS C N 1 ATOM 9531 C CA . LYS C 1 360 ? -13.874 68.897 44.805 1.00 24.96 ? 393 LYS C CA 1 ATOM 9532 C C . LYS C 1 360 ? -12.695 68.022 45.275 1.00 23.00 ? 393 LYS C C 1 ATOM 9533 O O . LYS C 1 360 ? -11.757 68.516 45.868 1.00 21.94 ? 393 LYS C O 1 ATOM 9534 C CB . LYS C 1 360 ? -15.094 68.760 45.694 1.00 25.50 ? 393 LYS C CB 1 ATOM 9535 C CG . LYS C 1 360 ? -16.119 69.864 45.427 1.00 27.03 ? 393 LYS C CG 1 ATOM 9536 C CD . LYS C 1 360 ? -16.376 70.773 46.634 1.00 29.38 ? 393 LYS C CD 1 ATOM 9537 C CE . LYS C 1 360 ? -16.714 72.168 46.145 1.00 30.66 ? 393 LYS C CE 1 ATOM 9538 N NZ . LYS C 1 360 ? -15.468 72.862 45.705 1.00 28.72 1 393 LYS C NZ 1 ATOM 9539 N N . GLN C 1 361 ? -12.719 66.746 44.933 1.00 21.41 ? 394 GLN C N 1 ATOM 9540 C CA . GLN C 1 361 ? -11.597 65.864 45.248 1.00 22.18 ? 394 GLN C CA 1 ATOM 9541 C C . GLN C 1 361 ? -10.261 66.298 44.612 1.00 20.39 ? 394 GLN C C 1 ATOM 9542 O O . GLN C 1 361 ? -9.197 66.119 45.259 1.00 16.39 ? 394 GLN C O 1 ATOM 9543 C CB . GLN C 1 361 ? -11.927 64.413 44.814 1.00 24.71 ? 394 GLN C CB 1 ATOM 9544 C CG . GLN C 1 361 ? -12.993 63.747 45.646 1.00 27.72 ? 394 GLN C CG 1 ATOM 9545 C CD . GLN C 1 361 ? -13.276 62.341 45.173 1.00 34.56 ? 394 GLN C CD 1 ATOM 9546 O OE1 . GLN C 1 361 ? -14.294 62.078 44.534 1.00 40.38 ? 394 GLN C OE1 1 ATOM 9547 N NE2 . GLN C 1 361 ? -12.367 61.425 45.475 1.00 38.34 ? 394 GLN C NE2 1 ATOM 9548 N N . PHE C 1 362 ? -10.328 66.817 43.348 1.00 19.88 ? 395 PHE C N 1 ATOM 9549 C CA . PHE C 1 362 ? -9.152 67.436 42.669 1.00 20.00 ? 395 PHE C CA 1 ATOM 9550 C C . PHE C 1 362 ? -8.566 68.574 43.540 1.00 19.47 ? 395 PHE C C 1 ATOM 9551 O O . PHE C 1 362 ? -7.344 68.725 43.617 1.00 17.81 ? 395 PHE C O 1 ATOM 9552 C CB . PHE C 1 362 ? -9.448 68.053 41.290 1.00 19.18 ? 395 PHE C CB 1 ATOM 9553 C CG . PHE C 1 362 ? -9.879 67.088 40.211 1.00 19.80 ? 395 PHE C CG 1 ATOM 9554 C CD1 . PHE C 1 362 ? -9.640 65.740 40.283 1.00 18.33 ? 395 PHE C CD1 1 ATOM 9555 C CD2 . PHE C 1 362 ? -10.549 67.587 39.048 1.00 19.73 ? 395 PHE C CD2 1 ATOM 9556 C CE1 . PHE C 1 362 ? -10.058 64.934 39.246 1.00 17.13 ? 395 PHE C CE1 1 ATOM 9557 C CE2 . PHE C 1 362 ? -10.929 66.766 38.025 1.00 17.49 ? 395 PHE C CE2 1 ATOM 9558 C CZ . PHE C 1 362 ? -10.704 65.442 38.144 1.00 16.68 ? 395 PHE C CZ 1 ATOM 9559 N N . THR C 1 363 ? -9.443 69.378 44.169 1.00 18.61 ? 396 THR C N 1 ATOM 9560 C CA . THR C 1 363 ? -8.965 70.374 45.090 1.00 17.94 ? 396 THR C CA 1 ATOM 9561 C C . THR C 1 363 ? -8.323 69.782 46.359 1.00 17.59 ? 396 THR C C 1 ATOM 9562 O O . THR C 1 363 ? -7.778 70.515 47.121 1.00 18.33 ? 396 THR C O 1 ATOM 9563 C CB . THR C 1 363 ? -10.070 71.290 45.589 1.00 19.23 ? 396 THR C CB 1 ATOM 9564 O OG1 . THR C 1 363 ? -10.682 70.695 46.786 1.00 18.12 ? 396 THR C OG1 1 ATOM 9565 C CG2 . THR C 1 363 ? -11.047 71.663 44.435 1.00 18.47 ? 396 THR C CG2 1 ATOM 9566 N N . ILE C 1 364 ? -8.385 68.486 46.614 1.00 18.42 ? 397 ILE C N 1 ATOM 9567 C CA . ILE C 1 364 ? -7.660 67.887 47.782 1.00 19.16 ? 397 ILE C CA 1 ATOM 9568 C C . ILE C 1 364 ? -6.205 68.359 47.613 1.00 21.98 ? 397 ILE C C 1 ATOM 9569 O O . ILE C 1 364 ? -5.788 68.673 46.495 1.00 20.10 ? 397 ILE C O 1 ATOM 9570 C CB . ILE C 1 364 ? -7.856 66.331 47.875 1.00 18.18 ? 397 ILE C CB 1 ATOM 9571 C CG1 . ILE C 1 364 ? -9.273 66.029 48.399 1.00 19.98 ? 397 ILE C CG1 1 ATOM 9572 C CG2 . ILE C 1 364 ? -6.880 65.672 48.780 1.00 18.25 ? 397 ILE C CG2 1 ATOM 9573 C CD1 . ILE C 1 364 ? -9.673 64.586 48.693 1.00 19.22 ? 397 ILE C CD1 1 ATOM 9574 N N . LEU C 1 365 ? -5.474 68.485 48.725 1.00 26.07 ? 398 LEU C N 1 ATOM 9575 C CA . LEU C 1 365 ? -4.026 68.788 48.732 1.00 28.67 ? 398 LEU C CA 1 ATOM 9576 C C . LEU C 1 365 ? -3.268 67.529 48.278 1.00 28.10 ? 398 LEU C C 1 ATOM 9577 O O . LEU C 1 365 ? -3.405 66.420 48.867 1.00 22.15 ? 398 LEU C O 1 ATOM 9578 C CB . LEU C 1 365 ? -3.590 69.195 50.143 1.00 35.16 ? 398 LEU C CB 1 ATOM 9579 C CG . LEU C 1 365 ? -2.402 70.090 50.568 1.00 38.87 ? 398 LEU C CG 1 ATOM 9580 C CD1 . LEU C 1 365 ? -1.592 70.717 49.420 1.00 38.96 ? 398 LEU C CD1 1 ATOM 9581 C CD2 . LEU C 1 365 ? -2.968 71.175 51.540 1.00 39.31 ? 398 LEU C CD2 1 ATOM 9582 N N . ASP C 1 366 ? -2.493 67.731 47.216 1.00 26.59 ? 399 ASP C N 1 ATOM 9583 C CA . ASP C 1 366 ? -1.760 66.669 46.520 1.00 28.37 ? 399 ASP C CA 1 ATOM 9584 C C . ASP C 1 366 ? -2.672 65.542 45.976 1.00 26.59 ? 399 ASP C C 1 ATOM 9585 O O . ASP C 1 366 ? -2.267 64.396 45.838 1.00 27.28 ? 399 ASP C O 1 ATOM 9586 C CB . ASP C 1 366 ? -0.560 66.165 47.365 1.00 29.72 ? 399 ASP C CB 1 ATOM 9587 C CG . ASP C 1 366 ? 0.516 67.292 47.620 1.00 33.72 ? 399 ASP C CG 1 ATOM 9588 O OD1 . ASP C 1 366 ? 0.604 68.279 46.835 1.00 30.40 ? 399 ASP C OD1 1 ATOM 9589 O OD2 . ASP C 1 366 ? 1.266 67.214 48.642 1.00 39.26 -1 399 ASP C OD2 1 ATOM 9590 N N . SER C 1 367 ? -3.893 65.889 45.610 1.00 26.14 ? 400 SER C N 1 ATOM 9591 C CA . SER C 1 367 ? -4.851 64.899 45.086 1.00 25.86 ? 400 SER C CA 1 ATOM 9592 C C . SER C 1 367 ? -4.282 64.019 43.944 1.00 26.63 ? 400 SER C C 1 ATOM 9593 O O . SER C 1 367 ? -3.763 64.532 42.934 1.00 28.65 ? 400 SER C O 1 ATOM 9594 C CB . SER C 1 367 ? -6.079 65.645 44.557 1.00 24.66 ? 400 SER C CB 1 ATOM 9595 O OG . SER C 1 367 ? -6.956 64.733 43.972 1.00 27.22 ? 400 SER C OG 1 ATOM 9596 N N . LYS C 1 368 ? -4.391 62.709 44.113 1.00 28.36 ? 401 LYS C N 1 ATOM 9597 C CA . LYS C 1 368 ? -4.129 61.704 43.045 1.00 30.95 ? 401 LYS C CA 1 ATOM 9598 C C . LYS C 1 368 ? -5.149 61.724 41.913 1.00 27.50 ? 401 LYS C C 1 ATOM 9599 O O . LYS C 1 368 ? -4.797 61.527 40.754 1.00 24.70 ? 401 LYS C O 1 ATOM 9600 C CB . LYS C 1 368 ? -4.006 60.268 43.619 1.00 33.61 ? 401 LYS C CB 1 ATOM 9601 C CG . LYS C 1 368 ? -2.553 59.872 43.897 1.00 40.84 ? 401 LYS C CG 1 ATOM 9602 C CD . LYS C 1 368 ? -1.751 60.948 44.669 1.00 44.50 ? 401 LYS C CD 1 ATOM 9603 C CE . LYS C 1 368 ? -0.284 61.014 44.245 1.00 46.83 ? 401 LYS C CE 1 ATOM 9604 N NZ . LYS C 1 368 ? 0.499 61.898 45.161 1.00 46.99 1 401 LYS C NZ 1 ATOM 9605 N N . GLN C 1 369 ? -6.405 61.956 42.267 1.00 26.21 ? 402 GLN C N 1 ATOM 9606 C CA . GLN C 1 369 ? -7.464 62.178 41.285 1.00 28.13 ? 402 GLN C CA 1 ATOM 9607 C C . GLN C 1 369 ? -7.057 63.278 40.267 1.00 24.74 ? 402 GLN C C 1 ATOM 9608 O O . GLN C 1 369 ? -7.223 63.065 39.059 1.00 19.80 ? 402 GLN C O 1 ATOM 9609 C CB . GLN C 1 369 ? -8.813 62.544 41.987 1.00 32.60 ? 402 GLN C CB 1 ATOM 9610 C CG . GLN C 1 369 ? -9.427 61.453 42.891 1.00 34.91 ? 402 GLN C CG 1 ATOM 9611 C CD . GLN C 1 369 ? -10.025 60.323 42.080 1.00 38.30 ? 402 GLN C CD 1 ATOM 9612 O OE1 . GLN C 1 369 ? -9.311 59.635 41.335 1.00 40.31 ? 402 GLN C OE1 1 ATOM 9613 N NE2 . GLN C 1 369 ? -11.350 60.127 42.200 1.00 39.96 ? 402 GLN C NE2 1 ATOM 9614 N N . PHE C 1 370 ? -6.556 64.437 40.773 1.00 22.42 ? 403 PHE C N 1 ATOM 9615 C CA . PHE C 1 370 ? -6.252 65.595 39.912 1.00 21.97 ? 403 PHE C CA 1 ATOM 9616 C C . PHE C 1 370 ? -5.071 65.284 38.961 1.00 19.28 ? 403 PHE C C 1 ATOM 9617 O O . PHE C 1 370 ? -5.180 65.518 37.784 1.00 15.94 ? 403 PHE C O 1 ATOM 9618 C CB . PHE C 1 370 ? -6.063 66.963 40.658 1.00 21.33 ? 403 PHE C CB 1 ATOM 9619 C CG . PHE C 1 370 ? -5.523 68.002 39.754 1.00 19.52 ? 403 PHE C CG 1 ATOM 9620 C CD1 . PHE C 1 370 ? -6.358 68.623 38.841 1.00 21.22 ? 403 PHE C CD1 1 ATOM 9621 C CD2 . PHE C 1 370 ? -4.157 68.175 39.619 1.00 20.73 ? 403 PHE C CD2 1 ATOM 9622 C CE1 . PHE C 1 370 ? -5.849 69.520 37.878 1.00 20.78 ? 403 PHE C CE1 1 ATOM 9623 C CE2 . PHE C 1 370 ? -3.627 69.073 38.676 1.00 20.91 ? 403 PHE C CE2 1 ATOM 9624 C CZ . PHE C 1 370 ? -4.489 69.759 37.801 1.00 20.30 ? 403 PHE C CZ 1 ATOM 9625 N N . ILE C 1 371 ? -4.006 64.723 39.517 1.00 20.14 ? 404 ILE C N 1 ATOM 9626 C CA . ILE C 1 371 ? -2.902 64.126 38.787 1.00 23.90 ? 404 ILE C CA 1 ATOM 9627 C C . ILE C 1 371 ? -3.357 63.197 37.627 1.00 21.47 ? 404 ILE C C 1 ATOM 9628 O O . ILE C 1 371 ? -2.993 63.449 36.501 1.00 21.87 ? 404 ILE C O 1 ATOM 9629 C CB . ILE C 1 371 ? -1.898 63.412 39.759 1.00 29.85 ? 404 ILE C CB 1 ATOM 9630 C CG1 . ILE C 1 371 ? -1.204 64.429 40.688 1.00 36.23 ? 404 ILE C CG1 1 ATOM 9631 C CG2 . ILE C 1 371 ? -0.781 62.662 39.011 1.00 32.38 ? 404 ILE C CG2 1 ATOM 9632 C CD1 . ILE C 1 371 ? -0.483 65.590 39.990 1.00 40.42 ? 404 ILE C CD1 1 ATOM 9633 N N . LYS C 1 372 ? -4.124 62.148 37.894 1.00 18.88 ? 405 LYS C N 1 ATOM 9634 C CA . LYS C 1 372 ? -4.723 61.313 36.840 1.00 18.54 ? 405 LYS C CA 1 ATOM 9635 C C . LYS C 1 372 ? -5.384 62.114 35.723 1.00 15.06 ? 405 LYS C C 1 ATOM 9636 O O . LYS C 1 372 ? -5.179 61.839 34.554 1.00 11.54 ? 405 LYS C O 1 ATOM 9637 C CB . LYS C 1 372 ? -5.854 60.485 37.423 1.00 22.55 ? 405 LYS C CB 1 ATOM 9638 C CG . LYS C 1 372 ? -5.642 59.012 37.434 1.00 26.65 ? 405 LYS C CG 1 ATOM 9639 C CD . LYS C 1 372 ? -6.928 58.308 37.865 1.00 28.42 ? 405 LYS C CD 1 ATOM 9640 C CE . LYS C 1 372 ? -6.594 56.852 38.120 1.00 29.15 ? 405 LYS C CE 1 ATOM 9641 N NZ . LYS C 1 372 ? -7.709 56.237 38.864 1.00 31.27 1 405 LYS C NZ 1 ATOM 9642 N N . TYR C 1 373 ? -6.210 63.059 36.165 1.00 14.32 ? 406 TYR C N 1 ATOM 9643 C CA . TYR C 1 373 ? -6.988 63.982 35.331 1.00 15.15 ? 406 TYR C CA 1 ATOM 9644 C C . TYR C 1 373 ? -6.058 64.732 34.393 1.00 15.32 ? 406 TYR C C 1 ATOM 9645 O O . TYR C 1 373 ? -6.371 64.956 33.227 1.00 13.34 ? 406 TYR C O 1 ATOM 9646 C CB . TYR C 1 373 ? -7.705 65.052 36.199 1.00 14.89 ? 406 TYR C CB 1 ATOM 9647 C CG . TYR C 1 373 ? -8.502 66.062 35.342 1.00 15.38 ? 406 TYR C CG 1 ATOM 9648 C CD1 . TYR C 1 373 ? -9.610 65.650 34.619 1.00 15.90 ? 406 TYR C CD1 1 ATOM 9649 C CD2 . TYR C 1 373 ? -8.154 67.397 35.247 1.00 15.32 ? 406 TYR C CD2 1 ATOM 9650 C CE1 . TYR C 1 373 ? -10.305 66.504 33.813 1.00 15.51 ? 406 TYR C CE1 1 ATOM 9651 C CE2 . TYR C 1 373 ? -8.866 68.253 34.436 1.00 14.53 ? 406 TYR C CE2 1 ATOM 9652 C CZ . TYR C 1 373 ? -9.943 67.790 33.741 1.00 15.06 ? 406 TYR C CZ 1 ATOM 9653 O OH . TYR C 1 373 ? -10.711 68.584 32.918 1.00 15.97 ? 406 TYR C OH 1 ATOM 9654 N N . TYR C 1 374 ? -4.903 65.090 34.967 1.00 15.53 ? 407 TYR C N 1 ATOM 9655 C CA . TYR C 1 374 ? -3.884 65.834 34.272 1.00 17.40 ? 407 TYR C CA 1 ATOM 9656 C C . TYR C 1 374 ? -3.184 65.004 33.157 1.00 16.31 ? 407 TYR C C 1 ATOM 9657 O O . TYR C 1 374 ? -2.959 65.489 32.070 1.00 16.51 ? 407 TYR C O 1 ATOM 9658 C CB . TYR C 1 374 ? -2.849 66.434 35.269 1.00 17.60 ? 407 TYR C CB 1 ATOM 9659 C CG . TYR C 1 374 ? -2.128 67.631 34.689 1.00 18.83 ? 407 TYR C CG 1 ATOM 9660 C CD1 . TYR C 1 374 ? -2.846 68.760 34.263 1.00 20.69 ? 407 TYR C CD1 1 ATOM 9661 C CD2 . TYR C 1 374 ? -0.757 67.640 34.502 1.00 18.29 ? 407 TYR C CD2 1 ATOM 9662 C CE1 . TYR C 1 374 ? -2.203 69.857 33.733 1.00 19.84 ? 407 TYR C CE1 1 ATOM 9663 C CE2 . TYR C 1 374 ? -0.119 68.741 33.955 1.00 17.89 ? 407 TYR C CE2 1 ATOM 9664 C CZ . TYR C 1 374 ? -0.841 69.830 33.603 1.00 18.94 ? 407 TYR C CZ 1 ATOM 9665 O OH . TYR C 1 374 ? -0.239 70.911 33.045 1.00 23.42 ? 407 TYR C OH 1 ATOM 9666 N N . ASN C 1 375 ? -2.887 63.763 33.422 1.00 15.35 ? 408 ASN C N 1 ATOM 9667 C CA . ASN C 1 375 ? -2.324 62.966 32.407 1.00 16.58 ? 408 ASN C CA 1 ATOM 9668 C C . ASN C 1 375 ? -3.290 62.772 31.201 1.00 13.08 ? 408 ASN C C 1 ATOM 9669 O O . ASN C 1 375 ? -2.969 63.015 30.098 1.00 9.92 ? 408 ASN C O 1 ATOM 9670 C CB . ASN C 1 375 ? -1.889 61.645 33.029 1.00 20.72 ? 408 ASN C CB 1 ATOM 9671 C CG . ASN C 1 375 ? -0.694 61.802 33.943 1.00 26.10 ? 408 ASN C CG 1 ATOM 9672 O OD1 . ASN C 1 375 ? 0.073 62.778 33.878 1.00 30.06 ? 408 ASN C OD1 1 ATOM 9673 N ND2 . ASN C 1 375 ? -0.518 60.812 34.815 1.00 34.88 ? 408 ASN C ND2 1 ATOM 9674 N N . TYR C 1 376 ? -4.477 62.316 31.496 1.00 12.32 ? 409 TYR C N 1 ATOM 9675 C CA . TYR C 1 376 ? -5.563 62.247 30.576 1.00 12.18 ? 409 TYR C CA 1 ATOM 9676 C C . TYR C 1 376 ? -5.873 63.570 29.898 1.00 11.63 ? 409 TYR C C 1 ATOM 9677 O O . TYR C 1 376 ? -6.455 63.545 28.840 1.00 9.66 ? 409 TYR C O 1 ATOM 9678 C CB . TYR C 1 376 ? -6.825 61.885 31.360 1.00 12.79 ? 409 TYR C CB 1 ATOM 9679 C CG . TYR C 1 376 ? -6.840 60.516 31.975 1.00 13.75 ? 409 TYR C CG 1 ATOM 9680 C CD1 . TYR C 1 376 ? -5.990 59.504 31.536 1.00 14.40 ? 409 TYR C CD1 1 ATOM 9681 C CD2 . TYR C 1 376 ? -7.747 60.227 33.015 1.00 14.65 ? 409 TYR C CD2 1 ATOM 9682 C CE1 . TYR C 1 376 ? -6.032 58.240 32.133 1.00 15.71 ? 409 TYR C CE1 1 ATOM 9683 C CE2 . TYR C 1 376 ? -7.796 58.991 33.631 1.00 15.67 ? 409 TYR C CE2 1 ATOM 9684 C CZ . TYR C 1 376 ? -6.930 57.990 33.194 1.00 16.79 ? 409 TYR C CZ 1 ATOM 9685 O OH . TYR C 1 376 ? -7.019 56.747 33.786 1.00 18.33 ? 409 TYR C OH 1 ATOM 9686 N N . PHE C 1 377 ? -5.550 64.719 30.564 1.00 11.60 ? 410 PHE C N 1 ATOM 9687 C CA . PHE C 1 377 ? -5.768 66.004 29.941 1.00 11.46 ? 410 PHE C CA 1 ATOM 9688 C C . PHE C 1 377 ? -5.081 65.978 28.530 1.00 10.78 ? 410 PHE C C 1 ATOM 9689 O O . PHE C 1 377 ? -5.703 66.174 27.501 1.00 10.06 ? 410 PHE C O 1 ATOM 9690 C CB . PHE C 1 377 ? -5.366 67.159 30.883 1.00 12.06 ? 410 PHE C CB 1 ATOM 9691 C CG . PHE C 1 377 ? -5.493 68.569 30.262 1.00 12.07 ? 410 PHE C CG 1 ATOM 9692 C CD1 . PHE C 1 377 ? -6.728 69.144 30.024 1.00 12.27 ? 410 PHE C CD1 1 ATOM 9693 C CD2 . PHE C 1 377 ? -4.366 69.315 29.914 1.00 12.57 ? 410 PHE C CD2 1 ATOM 9694 C CE1 . PHE C 1 377 ? -6.853 70.434 29.466 1.00 12.19 ? 410 PHE C CE1 1 ATOM 9695 C CE2 . PHE C 1 377 ? -4.481 70.604 29.330 1.00 12.46 ? 410 PHE C CE2 1 ATOM 9696 C CZ . PHE C 1 377 ? -5.733 71.163 29.091 1.00 12.00 ? 410 PHE C CZ 1 ATOM 9697 N N . PHE C 1 378 ? -3.843 65.552 28.510 1.00 10.91 ? 411 PHE C N 1 ATOM 9698 C CA . PHE C 1 378 ? -3.067 65.374 27.290 1.00 11.18 ? 411 PHE C CA 1 ATOM 9699 C C . PHE C 1 378 ? -3.162 63.976 26.645 1.00 10.24 ? 411 PHE C C 1 ATOM 9700 O O . PHE C 1 378 ? -2.308 63.565 26.000 1.00 9.02 ? 411 PHE C O 1 ATOM 9701 C CB . PHE C 1 378 ? -1.611 65.688 27.682 1.00 12.39 ? 411 PHE C CB 1 ATOM 9702 C CG . PHE C 1 378 ? -1.382 67.093 28.263 1.00 13.05 ? 411 PHE C CG 1 ATOM 9703 C CD1 . PHE C 1 378 ? -1.379 68.224 27.438 1.00 12.86 ? 411 PHE C CD1 1 ATOM 9704 C CD2 . PHE C 1 378 ? -1.052 67.264 29.640 1.00 14.44 ? 411 PHE C CD2 1 ATOM 9705 C CE1 . PHE C 1 378 ? -1.128 69.470 27.964 1.00 14.13 ? 411 PHE C CE1 1 ATOM 9706 C CE2 . PHE C 1 378 ? -0.750 68.556 30.188 1.00 14.26 ? 411 PHE C CE2 1 ATOM 9707 C CZ . PHE C 1 378 ? -0.803 69.662 29.366 1.00 13.88 ? 411 PHE C CZ 1 ATOM 9708 N N . VAL C 1 379 ? -4.235 63.230 26.875 1.00 11.19 ? 412 VAL C N 1 ATOM 9709 C CA . VAL C 1 379 ? -4.416 61.874 26.321 1.00 11.41 ? 412 VAL C CA 1 ATOM 9710 C C . VAL C 1 379 ? -3.165 60.935 26.523 1.00 12.93 ? 412 VAL C C 1 ATOM 9711 O O . VAL C 1 379 ? -2.755 60.093 25.642 1.00 13.20 ? 412 VAL C O 1 ATOM 9712 C CB . VAL C 1 379 ? -4.955 61.840 24.849 1.00 10.09 ? 412 VAL C CB 1 ATOM 9713 C CG1 . VAL C 1 379 ? -5.851 60.631 24.674 1.00 9.81 ? 412 VAL C CG1 1 ATOM 9714 C CG2 . VAL C 1 379 ? -5.817 63.001 24.544 1.00 10.38 ? 412 VAL C CG2 1 ATOM 9715 N N . SER C 1 380 ? -2.608 61.092 27.712 1.00 13.75 ? 413 SER C N 1 ATOM 9716 C CA . SER C 1 380 ? -1.471 60.349 28.268 1.00 14.65 ? 413 SER C CA 1 ATOM 9717 C C . SER C 1 380 ? -0.196 60.551 27.497 1.00 16.74 ? 413 SER C C 1 ATOM 9718 O O . SER C 1 380 ? 0.654 59.644 27.521 1.00 17.55 ? 413 SER C O 1 ATOM 9719 C CB . SER C 1 380 ? -1.778 58.844 28.398 1.00 14.55 ? 413 SER C CB 1 ATOM 9720 O OG . SER C 1 380 ? -2.934 58.618 29.199 1.00 14.15 ? 413 SER C OG 1 ATOM 9721 N N . TYR C 1 381 ? -0.024 61.689 26.818 1.00 18.78 ? 414 TYR C N 1 ATOM 9722 C CA . TYR C 1 381 ? 1.184 61.935 25.993 1.00 21.99 ? 414 TYR C CA 1 ATOM 9723 C C . TYR C 1 381 ? 2.538 61.699 26.712 1.00 26.60 ? 414 TYR C C 1 ATOM 9724 O O . TYR C 1 381 ? 3.419 61.056 26.161 1.00 26.61 ? 414 TYR C O 1 ATOM 9725 C CB . TYR C 1 381 ? 1.105 63.261 25.239 1.00 20.69 ? 414 TYR C CB 1 ATOM 9726 C CG . TYR C 1 381 ? 2.290 63.518 24.398 1.00 18.92 ? 414 TYR C CG 1 ATOM 9727 C CD1 . TYR C 1 381 ? 2.530 62.786 23.252 1.00 19.74 ? 414 TYR C CD1 1 ATOM 9728 C CD2 . TYR C 1 381 ? 3.179 64.455 24.774 1.00 17.92 ? 414 TYR C CD2 1 ATOM 9729 C CE1 . TYR C 1 381 ? 3.632 63.026 22.493 1.00 20.46 ? 414 TYR C CE1 1 ATOM 9730 C CE2 . TYR C 1 381 ? 4.288 64.705 24.048 1.00 18.95 ? 414 TYR C CE2 1 ATOM 9731 C CZ . TYR C 1 381 ? 4.520 64.011 22.905 1.00 20.58 ? 414 TYR C CZ 1 ATOM 9732 O OH . TYR C 1 381 ? 5.643 64.330 22.202 1.00 20.95 ? 414 TYR C OH 1 ATOM 9733 N N . ASP C 1 382 ? 2.683 62.168 27.939 1.00 34.68 ? 415 ASP C N 1 ATOM 9734 C CA . ASP C 1 382 ? 3.755 61.668 28.817 1.00 42.33 ? 415 ASP C CA 1 ATOM 9735 C C . ASP C 1 382 ? 3.177 61.123 30.149 1.00 46.43 ? 415 ASP C C 1 ATOM 9736 O O . ASP C 1 382 ? 2.154 61.540 30.641 1.00 48.55 ? 415 ASP C O 1 ATOM 9737 C CB . ASP C 1 382 ? 4.869 62.679 29.063 1.00 47.83 ? 415 ASP C CB 1 ATOM 9738 C CG . ASP C 1 382 ? 5.799 62.823 27.859 1.00 51.52 ? 415 ASP C CG 1 ATOM 9739 O OD1 . ASP C 1 382 ? 5.431 62.322 26.798 1.00 52.80 ? 415 ASP C OD1 1 ATOM 9740 O OD2 . ASP C 1 382 ? 6.888 63.433 27.950 1.00 45.95 -1 415 ASP C OD2 1 ATOM 9741 N N . SER C 1 383 ? 3.848 60.150 30.724 1.00 57.17 ? 416 SER C N 1 ATOM 9742 C CA . SER C 1 383 ? 3.482 59.574 32.012 1.00 54.78 ? 416 SER C CA 1 ATOM 9743 C C . SER C 1 383 ? 3.801 60.605 33.081 1.00 58.07 ? 416 SER C C 1 ATOM 9744 O O . SER C 1 383 ? 2.928 61.155 33.752 1.00 62.43 ? 416 SER C O 1 ATOM 9745 C CB . SER C 1 383 ? 4.314 58.316 32.235 1.00 54.65 ? 416 SER C CB 1 ATOM 9746 O OG . SER C 1 383 ? 4.929 57.920 31.018 1.00 52.67 ? 416 SER C OG 1 ATOM 9747 N N . SER C 1 384 ? 5.081 60.926 33.156 1.00 57.64 ? 417 SER C N 1 ATOM 9748 C CA . SER C 1 384 ? 5.632 61.706 34.227 1.00 50.26 ? 417 SER C CA 1 ATOM 9749 C C . SER C 1 384 ? 5.397 63.171 33.966 1.00 45.79 ? 417 SER C C 1 ATOM 9750 O O . SER C 1 384 ? 6.256 64.027 34.255 1.00 47.86 ? 417 SER C O 1 ATOM 9751 C CB . SER C 1 384 ? 7.132 61.431 34.290 1.00 53.26 ? 417 SER C CB 1 ATOM 9752 O OG . SER C 1 384 ? 7.739 61.781 33.049 1.00 51.85 ? 417 SER C OG 1 ATOM 9753 N N . VAL C 1 385 ? 4.249 63.513 33.415 1.00 43.89 ? 418 VAL C N 1 ATOM 9754 C CA . VAL C 1 385 ? 4.002 64.938 33.303 1.00 41.90 ? 418 VAL C CA 1 ATOM 9755 C C . VAL C 1 385 ? 3.477 65.330 34.655 1.00 35.48 ? 418 VAL C C 1 ATOM 9756 O O . VAL C 1 385 ? 2.598 64.703 35.204 1.00 36.84 ? 418 VAL C O 1 ATOM 9757 C CB . VAL C 1 385 ? 3.104 65.384 32.123 1.00 43.24 ? 418 VAL C CB 1 ATOM 9758 C CG1 . VAL C 1 385 ? 1.606 65.396 32.513 1.00 40.62 ? 418 VAL C CG1 1 ATOM 9759 C CG2 . VAL C 1 385 ? 3.621 66.757 31.599 1.00 42.18 ? 418 VAL C CG2 1 ATOM 9760 N N . THR C 1 386 ? 4.119 66.341 35.188 1.00 33.87 ? 419 THR C N 1 ATOM 9761 C CA . THR C 1 386 ? 3.929 66.831 36.536 1.00 31.43 ? 419 THR C CA 1 ATOM 9762 C C . THR C 1 386 ? 3.123 68.124 36.318 1.00 28.05 ? 419 THR C C 1 ATOM 9763 O O . THR C 1 386 ? 2.894 68.495 35.189 1.00 27.95 ? 419 THR C O 1 ATOM 9764 C CB . THR C 1 386 ? 5.314 67.035 37.233 1.00 27.72 ? 419 THR C CB 1 ATOM 9765 O OG1 . THR C 1 386 ? 5.149 67.576 38.537 1.00 29.60 ? 419 THR C OG1 1 ATOM 9766 C CG2 . THR C 1 386 ? 6.185 67.959 36.480 1.00 27.82 ? 419 THR C CG2 1 ATOM 9767 N N . CYS C 1 387 ? 2.680 68.766 37.385 1.00 25.27 ? 420 CYS C N 1 ATOM 9768 C CA . CYS C 1 387 ? 1.865 69.984 37.284 1.00 24.28 ? 420 CYS C CA 1 ATOM 9769 C C . CYS C 1 387 ? 2.220 70.808 38.524 1.00 24.28 ? 420 CYS C C 1 ATOM 9770 O O . CYS C 1 387 ? 2.545 70.220 39.550 1.00 22.72 ? 420 CYS C O 1 ATOM 9771 C CB . CYS C 1 387 ? 0.381 69.636 37.267 1.00 22.21 ? 420 CYS C CB 1 ATOM 9772 S SG . CYS C 1 387 ? -0.715 71.022 36.985 1.00 21.97 ? 420 CYS C SG 1 ATOM 9773 N N . ASP C 1 388 ? 2.247 72.133 38.394 1.00 23.50 ? 421 ASP C N 1 ATOM 9774 C CA . ASP C 1 388 ? 2.603 73.038 39.491 1.00 25.17 ? 421 ASP C CA 1 ATOM 9775 C C . ASP C 1 388 ? 1.319 73.635 40.064 1.00 24.15 ? 421 ASP C C 1 ATOM 9776 O O . ASP C 1 388 ? 0.254 73.459 39.486 1.00 23.76 ? 421 ASP C O 1 ATOM 9777 C CB . ASP C 1 388 ? 3.617 74.121 39.028 1.00 27.66 ? 421 ASP C CB 1 ATOM 9778 C CG . ASP C 1 388 ? 2.972 75.339 38.294 1.00 29.51 ? 421 ASP C CG 1 ATOM 9779 O OD1 . ASP C 1 388 ? 1.902 75.288 37.615 1.00 31.89 ? 421 ASP C OD1 1 ATOM 9780 O OD2 . ASP C 1 388 ? 3.593 76.398 38.405 1.00 31.61 -1 421 ASP C OD2 1 ATOM 9781 N N . LYS C 1 389 ? 1.428 74.282 41.215 1.00 24.73 ? 422 LYS C N 1 ATOM 9782 C CA . LYS C 1 389 ? 0.284 74.881 41.908 1.00 27.18 ? 422 LYS C CA 1 ATOM 9783 C C . LYS C 1 389 ? -0.520 75.859 41.053 1.00 26.52 ? 422 LYS C C 1 ATOM 9784 O O . LYS C 1 389 ? -1.729 75.841 41.062 1.00 27.02 ? 422 LYS C O 1 ATOM 9785 C CB . LYS C 1 389 ? 0.752 75.691 43.101 1.00 30.23 ? 422 LYS C CB 1 ATOM 9786 C CG . LYS C 1 389 ? 1.330 74.911 44.251 1.00 34.62 ? 422 LYS C CG 1 ATOM 9787 C CD . LYS C 1 389 ? 1.809 75.864 45.376 1.00 39.05 ? 422 LYS C CD 1 ATOM 9788 C CE . LYS C 1 389 ? 2.586 77.087 44.878 1.00 39.21 ? 422 LYS C CE 1 ATOM 9789 N NZ . LYS C 1 389 ? 3.771 77.340 45.751 1.00 44.81 1 422 LYS C NZ 1 ATOM 9790 N N . THR C 1 390 ? 0.169 76.756 40.368 1.00 25.36 ? 423 THR C N 1 ATOM 9791 C CA . THR C 1 390 ? -0.467 77.759 39.525 1.00 26.39 ? 423 THR C CA 1 ATOM 9792 C C . THR C 1 390 ? -1.361 77.105 38.420 1.00 25.88 ? 423 THR C C 1 ATOM 9793 O O . THR C 1 390 ? -2.546 77.456 38.242 1.00 22.47 ? 423 THR C O 1 ATOM 9794 C CB . THR C 1 390 ? 0.651 78.659 38.906 1.00 27.69 ? 423 THR C CB 1 ATOM 9795 O OG1 . THR C 1 390 ? 1.529 79.079 39.948 1.00 30.00 ? 423 THR C OG1 1 ATOM 9796 C CG2 . THR C 1 390 ? 0.115 79.908 38.251 1.00 27.57 ? 423 THR C CG2 1 ATOM 9797 N N . CYS C 1 391 ? -0.778 76.163 37.677 1.00 26.19 ? 424 CYS C N 1 ATOM 9798 C CA . CYS C 1 391 ? -1.523 75.479 36.632 1.00 27.07 ? 424 CYS C CA 1 ATOM 9799 C C . CYS C 1 391 ? -2.760 74.777 37.224 1.00 24.83 ? 424 CYS C C 1 ATOM 9800 O O . CYS C 1 391 ? -3.863 74.822 36.651 1.00 21.66 ? 424 CYS C O 1 ATOM 9801 C CB . CYS C 1 391 ? -0.637 74.475 35.894 1.00 29.12 ? 424 CYS C CB 1 ATOM 9802 S SG . CYS C 1 391 ? 0.545 75.227 34.752 1.00 31.74 ? 424 CYS C SG 1 ATOM 9803 N N . LYS C 1 392 ? -2.573 74.135 38.371 1.00 22.90 ? 425 LYS C N 1 ATOM 9804 C CA . LYS C 1 392 ? -3.663 73.395 38.974 1.00 22.80 ? 425 LYS C CA 1 ATOM 9805 C C . LYS C 1 392 ? -4.791 74.332 39.333 1.00 21.55 ? 425 LYS C C 1 ATOM 9806 O O . LYS C 1 392 ? -5.949 74.048 39.066 1.00 20.22 ? 425 LYS C O 1 ATOM 9807 C CB . LYS C 1 392 ? -3.205 72.654 40.210 1.00 22.82 ? 425 LYS C CB 1 ATOM 9808 C CG . LYS C 1 392 ? -4.355 72.027 40.958 1.00 21.44 ? 425 LYS C CG 1 ATOM 9809 C CD . LYS C 1 392 ? -3.827 71.012 41.915 1.00 20.94 ? 425 LYS C CD 1 ATOM 9810 C CE . LYS C 1 392 ? -4.935 70.655 42.878 1.00 22.11 ? 425 LYS C CE 1 ATOM 9811 N NZ . LYS C 1 392 ? -4.518 69.499 43.680 1.00 21.95 1 425 LYS C NZ 1 ATOM 9812 N N . ALA C 1 393 ? -4.426 75.467 39.897 1.00 21.72 ? 426 ALA C N 1 ATOM 9813 C CA . ALA C 1 393 ? -5.394 76.527 40.187 1.00 23.74 ? 426 ALA C CA 1 ATOM 9814 C C . ALA C 1 393 ? -6.179 76.913 38.903 1.00 22.19 ? 426 ALA C C 1 ATOM 9815 O O . ALA C 1 393 ? -7.401 76.937 38.905 1.00 19.97 ? 426 ALA C O 1 ATOM 9816 C CB . ALA C 1 393 ? -4.685 77.744 40.830 1.00 23.39 ? 426 ALA C CB 1 ATOM 9817 N N . PHE C 1 394 ? -5.466 77.159 37.814 1.00 23.05 ? 427 PHE C N 1 ATOM 9818 C CA . PHE C 1 394 ? -6.120 77.445 36.523 1.00 27.15 ? 427 PHE C CA 1 ATOM 9819 C C . PHE C 1 394 ? -7.053 76.308 36.068 1.00 27.06 ? 427 PHE C C 1 ATOM 9820 O O . PHE C 1 394 ? -8.132 76.587 35.556 1.00 25.26 ? 427 PHE C O 1 ATOM 9821 C CB . PHE C 1 394 ? -5.103 77.720 35.355 1.00 28.38 ? 427 PHE C CB 1 ATOM 9822 C CG . PHE C 1 394 ? -4.178 78.887 35.590 1.00 31.25 ? 427 PHE C CG 1 ATOM 9823 C CD1 . PHE C 1 394 ? -4.520 79.937 36.476 1.00 31.34 ? 427 PHE C CD1 1 ATOM 9824 C CD2 . PHE C 1 394 ? -2.946 78.942 34.924 1.00 32.24 ? 427 PHE C CD2 1 ATOM 9825 C CE1 . PHE C 1 394 ? -3.636 80.983 36.706 1.00 31.94 ? 427 PHE C CE1 1 ATOM 9826 C CE2 . PHE C 1 394 ? -2.074 80.003 35.134 1.00 33.10 ? 427 PHE C CE2 1 ATOM 9827 C CZ . PHE C 1 394 ? -2.424 81.028 36.025 1.00 33.45 ? 427 PHE C CZ 1 ATOM 9828 N N . GLN C 1 395 ? -6.608 75.053 36.215 1.00 26.13 ? 428 GLN C N 1 ATOM 9829 C CA . GLN C 1 395 ? -7.382 73.897 35.800 1.00 28.12 ? 428 GLN C CA 1 ATOM 9830 C C . GLN C 1 395 ? -8.691 73.779 36.627 1.00 29.50 ? 428 GLN C C 1 ATOM 9831 O O . GLN C 1 395 ? -9.813 73.807 36.063 1.00 26.05 ? 428 GLN C O 1 ATOM 9832 C CB . GLN C 1 395 ? -6.544 72.624 35.940 1.00 30.06 ? 428 GLN C CB 1 ATOM 9833 C CG . GLN C 1 395 ? -5.384 72.455 34.934 1.00 31.48 ? 428 GLN C CG 1 ATOM 9834 C CD . GLN C 1 395 ? -5.875 72.016 33.557 1.00 31.54 ? 428 GLN C CD 1 ATOM 9835 O OE1 . GLN C 1 395 ? -6.890 71.308 33.444 1.00 29.49 ? 428 GLN C OE1 1 ATOM 9836 N NE2 . GLN C 1 395 ? -5.164 72.429 32.511 1.00 30.07 ? 428 GLN C NE2 1 ATOM 9837 N N . ILE C 1 396 ? -8.515 73.705 37.950 1.00 28.68 ? 429 ILE C N 1 ATOM 9838 C CA . ILE C 1 396 ? -9.617 73.659 38.933 1.00 30.09 ? 429 ILE C CA 1 ATOM 9839 C C . ILE C 1 396 ? -10.669 74.774 38.728 1.00 27.12 ? 429 ILE C C 1 ATOM 9840 O O . ILE C 1 396 ? -11.899 74.537 38.724 1.00 25.75 ? 429 ILE C O 1 ATOM 9841 C CB . ILE C 1 396 ? -9.084 73.783 40.411 1.00 30.97 ? 429 ILE C CB 1 ATOM 9842 C CG1 . ILE C 1 396 ? -8.178 72.591 40.822 1.00 30.43 ? 429 ILE C CG1 1 ATOM 9843 C CG2 . ILE C 1 396 ? -10.252 73.974 41.398 1.00 33.18 ? 429 ILE C CG2 1 ATOM 9844 C CD1 . ILE C 1 396 ? -8.652 71.218 40.395 1.00 30.42 ? 429 ILE C CD1 1 ATOM 9845 N N . CYS C 1 397 ? -10.188 75.999 38.617 1.00 24.74 ? 430 CYS C N 1 ATOM 9846 C CA . CYS C 1 397 ? -11.102 77.100 38.495 1.00 24.97 ? 430 CYS C CA 1 ATOM 9847 C C . CYS C 1 397 ? -11.951 76.990 37.230 1.00 23.50 ? 430 CYS C C 1 ATOM 9848 O O . CYS C 1 397 ? -13.170 77.127 37.320 1.00 22.95 ? 430 CYS C O 1 ATOM 9849 C CB . CYS C 1 397 ? -10.361 78.444 38.704 1.00 27.74 ? 430 CYS C CB 1 ATOM 9850 S SG . CYS C 1 397 ? -9.856 78.658 40.474 1.00 29.55 ? 430 CYS C SG 1 ATOM 9851 N N . ALA C 1 398 ? -11.322 76.646 36.098 1.00 23.30 ? 431 ALA C N 1 ATOM 9852 C CA . ALA C 1 398 ? -12.014 76.376 34.808 1.00 25.11 ? 431 ALA C CA 1 ATOM 9853 C C . ALA C 1 398 ? -13.082 75.240 34.802 1.00 21.82 ? 431 ALA C C 1 ATOM 9854 O O . ALA C 1 398 ? -14.100 75.346 34.105 1.00 22.67 ? 431 ALA C O 1 ATOM 9855 C CB . ALA C 1 398 ? -11.000 76.098 33.653 1.00 27.41 ? 431 ALA C CB 1 ATOM 9856 N N . ILE C 1 399 ? -12.814 74.142 35.479 1.00 19.54 ? 432 ILE C N 1 ATOM 9857 C CA . ILE C 1 399 ? -13.740 73.044 35.523 1.00 20.08 ? 432 ILE C CA 1 ATOM 9858 C C . ILE C 1 399 ? -15.002 73.519 36.206 1.00 21.29 ? 432 ILE C C 1 ATOM 9859 O O . ILE C 1 399 ? -16.084 73.190 35.776 1.00 19.30 ? 432 ILE C O 1 ATOM 9860 C CB . ILE C 1 399 ? -13.143 71.860 36.324 1.00 21.34 ? 432 ILE C CB 1 ATOM 9861 C CG1 . ILE C 1 399 ? -11.949 71.232 35.573 1.00 22.06 ? 432 ILE C CG1 1 ATOM 9862 C CG2 . ILE C 1 399 ? -14.179 70.772 36.603 1.00 21.73 ? 432 ILE C CG2 1 ATOM 9863 C CD1 . ILE C 1 399 ? -11.100 70.291 36.388 1.00 23.31 ? 432 ILE C CD1 1 ATOM 9864 N N . MET C 1 400 ? -14.848 74.312 37.276 1.00 24.24 ? 433 MET C N 1 ATOM 9865 C CA . MET C 1 400 ? -15.974 74.586 38.220 1.00 27.96 ? 433 MET C CA 1 ATOM 9866 C C . MET C 1 400 ? -16.613 75.945 38.009 1.00 27.50 ? 433 MET C C 1 ATOM 9867 O O . MET C 1 400 ? -17.671 76.140 38.547 1.00 24.94 ? 433 MET C O 1 ATOM 9868 C CB . MET C 1 400 ? -15.555 74.533 39.706 1.00 29.56 ? 433 MET C CB 1 ATOM 9869 C CG . MET C 1 400 ? -15.394 73.160 40.356 1.00 32.62 ? 433 MET C CG 1 ATOM 9870 S SD . MET C 1 400 ? -14.497 73.261 41.965 1.00 37.58 ? 433 MET C SD 1 ATOM 9871 C CE . MET C 1 400 ? -15.470 72.014 42.772 1.00 44.76 ? 433 MET C CE 1 ATOM 9872 N N . ASN C 1 401 ? -15.970 76.865 37.269 1.00 28.02 ? 434 ASN C N 1 ATOM 9873 C CA . ASN C 1 401 ? -16.473 78.232 37.130 1.00 30.53 ? 434 ASN C CA 1 ATOM 9874 C C . ASN C 1 401 ? -16.435 78.752 35.730 1.00 35.72 ? 434 ASN C C 1 ATOM 9875 O O . ASN C 1 401 ? -15.342 79.010 35.224 1.00 41.21 ? 434 ASN C O 1 ATOM 9876 C CB . ASN C 1 401 ? -15.618 79.176 37.965 1.00 30.63 ? 434 ASN C CB 1 ATOM 9877 C CG . ASN C 1 401 ? -15.650 78.819 39.415 1.00 27.40 ? 434 ASN C CG 1 ATOM 9878 O OD1 . ASN C 1 401 ? -16.696 78.885 40.047 1.00 29.48 ? 434 ASN C OD1 1 ATOM 9879 N ND2 . ASN C 1 401 ? -14.549 78.371 39.924 1.00 26.15 ? 434 ASN C ND2 1 ATOM 9880 N N . LEU C 1 402 ? -17.600 78.957 35.117 1.00 35.49 ? 435 LEU C N 1 ATOM 9881 C CA . LEU C 1 402 ? -17.656 79.235 33.682 1.00 36.66 ? 435 LEU C CA 1 ATOM 9882 C C . LEU C 1 402 ? -17.879 80.725 33.365 1.00 40.13 ? 435 LEU C C 1 ATOM 9883 O O . LEU C 1 402 ? -17.443 81.231 32.350 1.00 34.97 ? 435 LEU C O 1 ATOM 9884 C CB . LEU C 1 402 ? -18.750 78.370 33.049 1.00 36.77 ? 435 LEU C CB 1 ATOM 9885 C CG . LEU C 1 402 ? -18.420 76.892 32.840 1.00 36.37 ? 435 LEU C CG 1 ATOM 9886 C CD1 . LEU C 1 402 ? -18.193 76.195 34.171 1.00 35.70 ? 435 LEU C CD1 1 ATOM 9887 C CD2 . LEU C 1 402 ? -19.541 76.229 32.063 1.00 36.41 ? 435 LEU C CD2 1 ATOM 9888 N N . ASP C 1 403 ? -18.597 81.424 34.227 1.00 47.24 ? 436 ASP C N 1 ATOM 9889 C CA . ASP C 1 403 ? -18.750 82.868 34.076 1.00 48.57 ? 436 ASP C CA 1 ATOM 9890 C C . ASP C 1 403 ? -17.559 83.615 34.717 1.00 52.40 ? 436 ASP C C 1 ATOM 9891 O O . ASP C 1 403 ? -16.800 83.038 35.513 1.00 52.22 ? 436 ASP C O 1 ATOM 9892 C CB . ASP C 1 403 ? -20.063 83.281 34.710 1.00 50.40 ? 436 ASP C CB 1 ATOM 9893 C CG . ASP C 1 403 ? -20.025 83.196 36.204 1.00 50.38 ? 436 ASP C CG 1 ATOM 9894 O OD1 . ASP C 1 403 ? -19.612 84.203 36.806 1.00 49.37 ? 436 ASP C OD1 1 ATOM 9895 O OD2 . ASP C 1 403 ? -20.377 82.124 36.754 1.00 54.53 -1 436 ASP C OD2 1 ATOM 9896 N N . ASN C 1 404 ? -17.397 84.886 34.360 1.00 56.25 ? 437 ASN C N 1 ATOM 9897 C CA . ASN C 1 404 ? -16.304 85.750 34.902 1.00 58.49 ? 437 ASN C CA 1 ATOM 9898 C C . ASN C 1 404 ? -16.172 85.958 36.461 1.00 53.13 ? 437 ASN C C 1 ATOM 9899 O O . ASN C 1 404 ? -15.054 85.958 37.007 1.00 46.37 ? 437 ASN C O 1 ATOM 9900 C CB . ASN C 1 404 ? -16.279 87.138 34.179 1.00 65.11 ? 437 ASN C CB 1 ATOM 9901 C CG . ASN C 1 404 ? -17.678 87.808 34.007 1.00 68.56 ? 437 ASN C CG 1 ATOM 9902 O OD1 . ASN C 1 404 ? -17.889 88.521 33.021 1.00 74.08 ? 437 ASN C OD1 1 ATOM 9903 N ND2 . ASN C 1 404 ? -18.612 87.603 34.941 1.00 64.64 ? 437 ASN C ND2 1 ATOM 9904 N N . ILE C 1 405 ? -17.298 86.108 37.163 1.00 48.55 ? 438 ILE C N 1 ATOM 9905 C CA . ILE C 1 405 ? -17.287 86.507 38.574 1.00 49.95 ? 438 ILE C CA 1 ATOM 9906 C C . ILE C 1 405 ? -16.757 85.316 39.413 1.00 47.46 ? 438 ILE C C 1 ATOM 9907 O O . ILE C 1 405 ? -15.771 85.450 40.180 1.00 46.00 ? 438 ILE C O 1 ATOM 9908 C CB . ILE C 1 405 ? -18.704 86.910 39.131 1.00 48.44 ? 438 ILE C CB 1 ATOM 9909 C CG1 . ILE C 1 405 ? -19.492 87.860 38.227 1.00 48.39 ? 438 ILE C CG1 1 ATOM 9910 C CG2 . ILE C 1 405 ? -18.565 87.562 40.501 1.00 50.07 ? 438 ILE C CG2 1 ATOM 9911 C CD1 . ILE C 1 405 ? -18.937 89.266 38.134 1.00 47.36 ? 438 ILE C CD1 1 ATOM 9912 N N . SER C 1 406 ? -17.469 84.191 39.281 1.00 40.97 ? 439 SER C N 1 ATOM 9913 C CA . SER C 1 406 ? -17.103 82.894 39.834 1.00 39.44 ? 439 SER C CA 1 ATOM 9914 C C . SER C 1 406 ? -15.645 82.539 39.603 1.00 38.78 ? 439 SER C C 1 ATOM 9915 O O . SER C 1 406 ? -14.990 81.983 40.503 1.00 37.81 ? 439 SER C O 1 ATOM 9916 C CB . SER C 1 406 ? -17.927 81.824 39.136 1.00 39.21 ? 439 SER C CB 1 ATOM 9917 O OG . SER C 1 406 ? -19.203 81.781 39.685 1.00 42.40 ? 439 SER C OG 1 ATOM 9918 N N . TYR C 1 407 ? -15.176 82.814 38.375 1.00 34.58 ? 440 TYR C N 1 ATOM 9919 C CA . TYR C 1 407 ? -13.860 82.396 37.926 1.00 32.64 ? 440 TYR C CA 1 ATOM 9920 C C . TYR C 1 407 ? -12.797 83.162 38.668 1.00 34.37 ? 440 TYR C C 1 ATOM 9921 O O . TYR C 1 407 ? -11.882 82.580 39.233 1.00 35.35 ? 440 TYR C O 1 ATOM 9922 C CB . TYR C 1 407 ? -13.695 82.620 36.426 1.00 31.34 ? 440 TYR C CB 1 ATOM 9923 C CG . TYR C 1 407 ? -12.348 82.238 36.007 1.00 28.99 ? 440 TYR C CG 1 ATOM 9924 C CD1 . TYR C 1 407 ? -11.987 80.896 35.936 1.00 29.41 ? 440 TYR C CD1 1 ATOM 9925 C CD2 . TYR C 1 407 ? -11.389 83.199 35.724 1.00 31.14 ? 440 TYR C CD2 1 ATOM 9926 C CE1 . TYR C 1 407 ? -10.701 80.515 35.601 1.00 27.93 ? 440 TYR C CE1 1 ATOM 9927 C CE2 . TYR C 1 407 ? -10.086 82.824 35.361 1.00 29.83 ? 440 TYR C CE2 1 ATOM 9928 C CZ . TYR C 1 407 ? -9.748 81.485 35.318 1.00 26.97 ? 440 TYR C CZ 1 ATOM 9929 O OH . TYR C 1 407 ? -8.472 81.124 34.959 1.00 26.65 ? 440 TYR C OH 1 ATOM 9930 N N . ALA C 1 408 ? -12.927 84.483 38.650 1.00 40.64 ? 441 ALA C N 1 ATOM 9931 C CA . ALA C 1 408 ? -12.061 85.389 39.442 1.00 43.48 ? 441 ALA C CA 1 ATOM 9932 C C . ALA C 1 408 ? -12.163 85.071 40.945 1.00 40.88 ? 441 ALA C C 1 ATOM 9933 O O . ALA C 1 408 ? -11.159 84.880 41.653 1.00 36.97 ? 441 ALA C O 1 ATOM 9934 C CB . ALA C 1 408 ? -12.446 86.839 39.173 1.00 44.42 ? 441 ALA C CB 1 ATOM 9935 N N . ASP C 1 409 ? -13.393 84.985 41.414 1.00 39.77 ? 442 ASP C N 1 ATOM 9936 C CA . ASP C 1 409 ? -13.615 84.572 42.767 1.00 43.19 ? 442 ASP C CA 1 ATOM 9937 C C . ASP C 1 409 ? -12.754 83.338 43.059 1.00 41.81 ? 442 ASP C C 1 ATOM 9938 O O . ASP C 1 409 ? -12.047 83.310 44.049 1.00 41.03 ? 442 ASP C O 1 ATOM 9939 C CB . ASP C 1 409 ? -15.099 84.316 42.993 1.00 45.96 ? 442 ASP C CB 1 ATOM 9940 C CG . ASP C 1 409 ? -15.395 83.890 44.402 1.00 53.97 ? 442 ASP C CG 1 ATOM 9941 O OD1 . ASP C 1 409 ? -16.046 84.665 45.149 1.00 57.98 ? 442 ASP C OD1 1 ATOM 9942 O OD2 . ASP C 1 409 ? -14.961 82.771 44.761 1.00 61.67 -1 442 ASP C OD2 1 ATOM 9943 N N . CYS C 1 410 ? -12.796 82.336 42.176 1.00 42.01 ? 443 CYS C N 1 ATOM 9944 C CA . CYS C 1 410 ? -11.939 81.137 42.290 1.00 37.27 ? 443 CYS C CA 1 ATOM 9945 C C . CYS C 1 410 ? -10.490 81.491 41.935 1.00 38.13 ? 443 CYS C C 1 ATOM 9946 O O . CYS C 1 410 ? -9.587 81.220 42.734 1.00 36.01 ? 443 CYS C O 1 ATOM 9947 C CB . CYS C 1 410 ? -12.454 79.993 41.386 1.00 34.24 ? 443 CYS C CB 1 ATOM 9948 S SG . CYS C 1 410 ? -11.616 78.362 41.547 1.00 29.36 ? 443 CYS C SG 1 HETATM 9949 ZN ZN . ZN D 2 . ? -3.909 14.617 14.254 1.00 14.92 ? 701 ZN A ZN 1 HETATM 9950 ZN ZN . ZN E 2 . ? -7.208 14.425 13.902 1.00 7.16 ? 702 ZN A ZN 1 HETATM 9951 C C1 . NAG F 3 . ? -21.870 -6.223 7.376 1.00 28.54 ? 703 NAG A C1 1 HETATM 9952 C C2 . NAG F 3 . ? -21.052 -7.557 7.468 1.00 30.42 ? 703 NAG A C2 1 HETATM 9953 C C3 . NAG F 3 . ? -21.611 -8.608 6.557 1.00 34.33 ? 703 NAG A C3 1 HETATM 9954 C C4 . NAG F 3 . ? -23.107 -8.797 6.821 1.00 36.97 ? 703 NAG A C4 1 HETATM 9955 C C5 . NAG F 3 . ? -23.757 -7.442 6.476 1.00 33.37 ? 703 NAG A C5 1 HETATM 9956 C C6 . NAG F 3 . ? -25.251 -7.547 6.338 1.00 32.62 ? 703 NAG A C6 1 HETATM 9957 C C7 . NAG F 3 . ? -18.677 -7.099 7.963 1.00 27.79 ? 703 NAG A C7 1 HETATM 9958 C C8 . NAG F 3 . ? -17.283 -6.782 7.342 1.00 25.78 ? 703 NAG A C8 1 HETATM 9959 N N2 . NAG F 3 . ? -19.645 -7.315 7.064 1.00 28.03 ? 703 NAG A N2 1 HETATM 9960 O O3 . NAG F 3 . ? -20.904 -9.781 6.870 1.00 38.41 ? 703 NAG A O3 1 HETATM 9961 O O4 . NAG F 3 . ? -23.651 -10.015 6.108 1.00 43.55 ? 703 NAG A O4 1 HETATM 9962 O O5 . NAG F 3 . ? -23.300 -6.514 7.544 1.00 29.28 ? 703 NAG A O5 1 HETATM 9963 O O6 . NAG F 3 . ? -25.853 -6.971 7.508 1.00 33.98 ? 703 NAG A O6 1 HETATM 9964 O O7 . NAG F 3 . ? -18.879 -7.049 9.200 1.00 29.31 ? 703 NAG A O7 1 HETATM 9965 C C1 . NAG G 3 . ? -15.590 19.762 -1.318 1.00 29.07 ? 704 NAG A C1 1 HETATM 9966 C C2 . NAG G 3 . ? -16.480 20.460 -2.339 1.00 31.62 ? 704 NAG A C2 1 HETATM 9967 C C3 . NAG G 3 . ? -17.903 19.929 -2.297 1.00 32.48 ? 704 NAG A C3 1 HETATM 9968 C C4 . NAG G 3 . ? -17.970 18.455 -2.451 1.00 31.37 ? 704 NAG A C4 1 HETATM 9969 C C5 . NAG G 3 . ? -17.161 17.760 -1.358 1.00 30.10 ? 704 NAG A C5 1 HETATM 9970 C C6 . NAG G 3 . ? -17.231 16.242 -1.516 1.00 27.36 ? 704 NAG A C6 1 HETATM 9971 C C7 . NAG G 3 . ? -15.666 22.786 -2.615 1.00 39.31 ? 704 NAG A C7 1 HETATM 9972 C C8 . NAG G 3 . ? -15.820 24.288 -2.206 1.00 37.07 ? 704 NAG A C8 1 HETATM 9973 N N2 . NAG G 3 . ? -16.504 21.903 -2.032 1.00 35.99 ? 704 NAG A N2 1 HETATM 9974 O O3 . NAG G 3 . ? -18.640 20.511 -3.402 1.00 36.41 ? 704 NAG A O3 1 HETATM 9975 O O4 . NAG G 3 . ? -19.342 18.082 -2.324 1.00 38.60 ? 704 NAG A O4 1 HETATM 9976 O O5 . NAG G 3 . ? -15.771 18.266 -1.399 1.00 28.73 ? 704 NAG A O5 1 HETATM 9977 O O6 . NAG G 3 . ? -15.897 15.805 -1.865 1.00 26.90 ? 704 NAG A O6 1 HETATM 9978 O O7 . NAG G 3 . ? -14.811 22.429 -3.417 1.00 44.16 ? 704 NAG A O7 1 HETATM 9979 C C1 . NAG H 3 . ? -28.251 12.252 22.266 1.00 16.65 ? 705 NAG A C1 1 HETATM 9980 C C2 . NAG H 3 . ? -28.334 12.056 23.758 1.00 18.09 ? 705 NAG A C2 1 HETATM 9981 C C3 . NAG H 3 . ? -28.711 10.668 24.258 1.00 17.72 ? 705 NAG A C3 1 HETATM 9982 C C4 . NAG H 3 . ? -30.043 10.247 23.753 1.00 18.64 ? 705 NAG A C4 1 HETATM 9983 C C5 . NAG H 3 . ? -30.056 10.431 22.230 1.00 19.94 ? 705 NAG A C5 1 HETATM 9984 C C6 . NAG H 3 . ? -31.492 10.851 21.822 1.00 20.76 ? 705 NAG A C6 1 HETATM 9985 C C7 . NAG H 3 . ? -26.874 13.384 25.251 1.00 18.17 ? 705 NAG A C7 1 HETATM 9986 C C8 . NAG H 3 . ? -25.453 13.796 25.661 1.00 17.84 ? 705 NAG A C8 1 HETATM 9987 N N2 . NAG H 3 . ? -27.007 12.466 24.299 1.00 18.83 ? 705 NAG A N2 1 HETATM 9988 O O3 . NAG H 3 . ? -28.905 10.937 25.621 1.00 18.72 ? 705 NAG A O3 1 HETATM 9989 O O4 . NAG H 3 . ? -30.641 8.865 24.266 1.00 17.77 ? 705 NAG A O4 1 HETATM 9990 O O5 . NAG H 3 . ? -29.337 11.592 21.678 1.00 17.97 ? 705 NAG A O5 1 HETATM 9991 O O6 . NAG H 3 . ? -31.619 10.151 20.630 1.00 21.68 ? 705 NAG A O6 1 HETATM 9992 O O7 . NAG H 3 . ? -27.821 13.833 25.843 1.00 19.77 ? 705 NAG A O7 1 HETATM 9993 C C1 . MLI I 4 . ? -5.281 11.108 15.161 1.00 35.65 ? 706 MLI A C1 1 HETATM 9994 C C2 . MLI I 4 . ? -5.907 12.418 14.570 1.00 33.67 ? 706 MLI A C2 1 HETATM 9995 C C3 . MLI I 4 . ? -3.970 10.726 14.437 1.00 39.32 ? 706 MLI A C3 1 HETATM 9996 O O6 . MLI I 4 . ? -6.912 12.159 13.916 1.00 41.39 ? 706 MLI A O6 1 HETATM 9997 O O7 . MLI I 4 . ? -5.482 13.611 14.778 1.00 22.49 ? 706 MLI A O7 1 HETATM 9998 O O8 . MLI I 4 . ? -3.555 11.527 13.579 1.00 41.47 ? 706 MLI A O8 1 HETATM 9999 O O9 . MLI I 4 . ? -3.381 9.663 14.741 1.00 39.33 ? 706 MLI A O9 1 HETATM 10000 ZN ZN . ZN J 2 . ? -57.739 41.821 11.602 1.00 19.01 ? 701 ZN B ZN 1 HETATM 10001 ZN ZN . ZN K 2 . ? -59.330 38.535 11.968 1.00 23.54 ? 702 ZN B ZN 1 HETATM 10002 C C1 . NAG L 3 . ? -68.388 64.691 5.018 1.00 42.49 ? 703 NAG B C1 1 HETATM 10003 C C2 . NAG L 3 . ? -69.983 64.634 5.143 1.00 43.93 ? 703 NAG B C2 1 HETATM 10004 C C3 . NAG L 3 . ? -70.671 65.688 4.292 1.00 49.33 ? 703 NAG B C3 1 HETATM 10005 C C4 . NAG L 3 . ? -70.046 67.075 4.572 1.00 53.21 ? 703 NAG B C4 1 HETATM 10006 C C5 . NAG L 3 . ? -68.535 66.950 4.147 1.00 48.65 ? 703 NAG B C5 1 HETATM 10007 C C6 . NAG L 3 . ? -67.825 68.272 4.019 1.00 47.30 ? 703 NAG B C6 1 HETATM 10008 C C7 . NAG L 3 . ? -70.727 62.302 5.666 1.00 39.91 ? 703 NAG B C7 1 HETATM 10009 C C8 . NAG L 3 . ? -71.129 60.924 5.039 1.00 36.92 ? 703 NAG B C8 1 HETATM 10010 N N2 . NAG L 3 . ? -70.451 63.277 4.747 1.00 40.97 ? 703 NAG B N2 1 HETATM 10011 O O3 . NAG L 3 . ? -72.066 65.681 4.616 1.00 52.51 ? 703 NAG B O3 1 HETATM 10012 O O4 . NAG L 3 . ? -70.851 68.182 3.929 1.00 56.73 ? 703 NAG B O4 1 HETATM 10013 O O5 . NAG L 3 . ? -67.891 66.092 5.147 1.00 43.33 ? 703 NAG B O5 1 HETATM 10014 O O6 . NAG L 3 . ? -67.295 68.556 5.314 1.00 46.37 ? 703 NAG B O6 1 HETATM 10015 O O7 . NAG L 3 . ? -70.662 62.459 6.909 1.00 35.75 ? 703 NAG B O7 1 HETATM 10016 C C1 . NAG M 3 . ? -48.839 46.260 -3.537 1.00 41.97 ? 704 NAG B C1 1 HETATM 10017 C C2 . NAG M 3 . ? -47.820 46.698 -4.592 1.00 44.07 ? 704 NAG B C2 1 HETATM 10018 C C3 . NAG M 3 . ? -47.610 48.220 -4.515 1.00 44.90 ? 704 NAG B C3 1 HETATM 10019 C C4 . NAG M 3 . ? -48.890 49.031 -4.569 1.00 45.34 ? 704 NAG B C4 1 HETATM 10020 C C5 . NAG M 3 . ? -49.884 48.602 -3.492 1.00 43.29 ? 704 NAG B C5 1 HETATM 10021 C C6 . NAG M 3 . ? -51.169 49.448 -3.622 1.00 38.16 ? 704 NAG B C6 1 HETATM 10022 C C7 . NAG M 3 . ? -46.239 44.720 -4.741 1.00 49.60 ? 704 NAG B C7 1 HETATM 10023 C C8 . NAG M 3 . ? -44.824 44.185 -4.397 1.00 48.08 ? 704 NAG B C8 1 HETATM 10024 N N2 . NAG M 3 . ? -46.526 45.997 -4.347 1.00 49.22 ? 704 NAG B N2 1 HETATM 10025 O O3 . NAG M 3 . ? -46.831 48.643 -5.627 1.00 47.63 ? 704 NAG B O3 1 HETATM 10026 O O4 . NAG M 3 . ? -48.557 50.417 -4.332 1.00 54.18 ? 704 NAG B O4 1 HETATM 10027 O O5 . NAG M 3 . ? -50.066 47.131 -3.580 1.00 43.65 ? 704 NAG B O5 1 HETATM 10028 O O6 . NAG M 3 . ? -52.281 48.570 -3.912 1.00 34.53 ? 704 NAG B O6 1 HETATM 10029 O O7 . NAG M 3 . ? -47.028 44.001 -5.337 1.00 46.47 ? 704 NAG B O7 1 HETATM 10030 C C1 . NAG N 3 . ? -48.835 61.082 19.983 1.00 33.32 ? 705 NAG B C1 1 HETATM 10031 C C2 . NAG N 3 . ? -49.097 61.112 21.518 1.00 33.74 ? 705 NAG B C2 1 HETATM 10032 C C3 . NAG N 3 . ? -50.278 61.998 21.741 1.00 31.24 ? 705 NAG B C3 1 HETATM 10033 C C4 . NAG N 3 . ? -49.946 63.390 21.304 1.00 32.52 ? 705 NAG B C4 1 HETATM 10034 C C5 . NAG N 3 . ? -49.913 63.279 19.772 1.00 35.10 ? 705 NAG B C5 1 HETATM 10035 C C6 . NAG N 3 . ? -49.885 64.630 18.987 1.00 35.84 ? 705 NAG B C6 1 HETATM 10036 C C7 . NAG N 3 . ? -48.731 58.998 22.982 1.00 34.50 ? 705 NAG B C7 1 HETATM 10037 C C8 . NAG N 3 . ? -48.015 59.809 24.046 1.00 33.76 ? 705 NAG B C8 1 HETATM 10038 N N2 . NAG N 3 . ? -49.277 59.667 21.912 1.00 35.55 ? 705 NAG B N2 1 HETATM 10039 O O3 . NAG N 3 . ? -50.449 62.041 23.045 1.00 34.10 ? 705 NAG B O3 1 HETATM 10040 O O4 . NAG N 3 . ? -50.807 64.547 21.896 1.00 32.17 ? 705 NAG B O4 1 HETATM 10041 O O5 . NAG N 3 . ? -48.769 62.441 19.476 1.00 36.05 ? 705 NAG B O5 1 HETATM 10042 O O6 . NAG N 3 . ? -48.546 65.056 18.808 1.00 33.00 ? 705 NAG B O6 1 HETATM 10043 O O7 . NAG N 3 . ? -48.840 57.772 23.140 1.00 33.41 ? 705 NAG B O7 1 HETATM 10044 C C1 . MLI O 4 . ? -60.896 41.875 12.250 1.00 28.70 ? 706 MLI B C1 1 HETATM 10045 C C2 . MLI O 4 . ? -62.229 41.245 12.676 1.00 32.91 ? 706 MLI B C2 1 HETATM 10046 C C3 . MLI O 4 . ? -59.896 40.679 12.428 1.00 27.91 ? 706 MLI B C3 1 HETATM 10047 O O6 . MLI O 4 . ? -62.896 40.698 11.748 1.00 31.77 ? 706 MLI B O6 1 HETATM 10048 O O7 . MLI O 4 . ? -62.392 41.083 13.932 1.00 35.98 ? 706 MLI B O7 1 HETATM 10049 O O8 . MLI O 4 . ? -58.689 40.808 12.206 1.00 21.31 ? 706 MLI B O8 1 HETATM 10050 O O9 . MLI O 4 . ? -60.372 39.588 12.821 1.00 35.47 ? 706 MLI B O9 1 HETATM 10051 C C1 . GOL P 5 . ? -32.783 48.940 22.615 1.00 37.13 ? 707 GOL B C1 1 HETATM 10052 O O1 . GOL P 5 . ? -33.698 48.249 23.476 1.00 41.09 ? 707 GOL B O1 1 HETATM 10053 C C2 . GOL P 5 . ? -32.195 47.999 21.537 1.00 36.69 ? 707 GOL B C2 1 HETATM 10054 O O2 . GOL P 5 . ? -31.385 48.775 20.674 1.00 32.74 ? 707 GOL B O2 1 HETATM 10055 C C3 . GOL P 5 . ? -31.340 46.878 22.148 1.00 35.88 ? 707 GOL B C3 1 HETATM 10056 O O3 . GOL P 5 . ? -32.196 45.705 22.226 1.00 36.27 ? 707 GOL B O3 1 HETATM 10057 ZN ZN . ZN Q 2 . ? -8.903 71.923 16.090 1.00 13.84 ? 701 ZN C ZN 1 HETATM 10058 ZN ZN . ZN R 2 . ? -10.612 74.493 16.519 1.00 23.58 ? 702 ZN C ZN 1 HETATM 10059 C C1 . NAG S 3 . ? 16.461 69.612 9.938 1.00 38.81 ? 703 NAG C C1 1 HETATM 10060 C C2 . NAG S 3 . ? 17.090 71.067 9.878 1.00 41.52 ? 703 NAG C C2 1 HETATM 10061 C C3 . NAG S 3 . ? 18.391 71.223 9.065 1.00 47.20 ? 703 NAG C C3 1 HETATM 10062 C C4 . NAG S 3 . ? 19.266 69.960 9.134 1.00 49.00 ? 703 NAG C C4 1 HETATM 10063 C C5 . NAG S 3 . ? 18.328 68.773 8.779 1.00 46.85 ? 703 NAG C C5 1 HETATM 10064 C C6 . NAG S 3 . ? 19.084 67.558 8.299 1.00 46.48 ? 703 NAG C C6 1 HETATM 10065 C C7 . NAG S 3 . ? 15.388 72.789 10.040 1.00 32.55 ? 703 NAG C C7 1 HETATM 10066 C C8 . NAG S 3 . ? 14.293 73.644 9.311 1.00 29.21 ? 703 NAG C C8 1 HETATM 10067 N N2 . NAG S 3 . ? 16.067 71.963 9.274 1.00 34.46 ? 703 NAG C N2 1 HETATM 10068 O O3 . NAG S 3 . ? 19.121 72.403 9.576 1.00 58.10 ? 703 NAG C O3 1 HETATM 10069 O O4 . NAG S 3 . ? 20.426 70.108 8.233 1.00 51.04 ? 703 NAG C O4 1 HETATM 10070 O O5 . NAG S 3 . ? 17.468 68.561 9.950 1.00 38.82 ? 703 NAG C O5 1 HETATM 10071 O O6 . NAG S 3 . ? 19.281 66.728 9.451 1.00 47.72 ? 703 NAG C O6 1 HETATM 10072 O O7 . NAG S 3 . ? 15.596 72.829 11.271 1.00 35.85 ? 703 NAG C O7 1 HETATM 10073 C C1 . NAG T 3 . ? -8.977 62.268 0.595 1.00 43.77 ? 704 NAG C C1 1 HETATM 10074 C C2 . NAG T 3 . ? -7.253 62.648 0.678 1.00 46.25 ? 704 NAG C C2 1 HETATM 10075 C C3 . NAG T 3 . ? -6.243 61.431 0.326 1.00 50.50 ? 704 NAG C C3 1 HETATM 10076 C C4 . NAG T 3 . ? -6.847 60.006 0.310 1.00 51.45 ? 704 NAG C C4 1 HETATM 10077 C C5 . NAG T 3 . ? -8.149 60.031 -0.561 1.00 52.36 ? 704 NAG C C5 1 HETATM 10078 C C6 . NAG T 3 . ? -8.371 58.624 -1.200 1.00 56.38 ? 704 NAG C C6 1 HETATM 10079 C C7 . NAG T 3 . ? -6.992 65.019 -0.523 1.00 44.17 ? 704 NAG C C7 1 HETATM 10080 C C8 . NAG T 3 . ? -6.262 65.622 -1.724 1.00 40.76 ? 704 NAG C C8 1 HETATM 10081 N N2 . NAG T 3 . ? -6.679 63.693 -0.286 1.00 46.73 ? 704 NAG C N2 1 HETATM 10082 O O3 . NAG T 3 . ? -4.980 61.458 1.093 1.00 51.13 ? 704 NAG C O3 1 HETATM 10083 O O4 . NAG T 3 . ? -5.810 59.106 -0.183 1.00 47.74 ? 704 NAG C O4 1 HETATM 10084 O O5 . NAG T 3 . ? -9.192 60.733 0.336 1.00 48.86 ? 704 NAG C O5 1 HETATM 10085 O O6 . NAG T 3 . ? -8.863 58.728 -2.573 1.00 55.25 ? 704 NAG C O6 1 HETATM 10086 O O7 . NAG T 3 . ? -7.705 65.759 0.160 1.00 41.94 ? 704 NAG C O7 1 HETATM 10087 C C1 . NAG U 3 . ? 3.571 54.772 24.485 1.00 22.63 ? 705 NAG C C1 1 HETATM 10088 C C2 . NAG U 3 . ? 3.782 54.784 26.028 1.00 24.39 ? 705 NAG C C2 1 HETATM 10089 C C3 . NAG U 3 . ? 5.210 55.109 26.535 1.00 23.62 ? 705 NAG C C3 1 HETATM 10090 C C4 . NAG U 3 . ? 6.257 54.165 25.886 1.00 26.00 ? 705 NAG C C4 1 HETATM 10091 C C5 . NAG U 3 . ? 6.040 54.345 24.319 1.00 27.46 ? 705 NAG C C5 1 HETATM 10092 C C6 . NAG U 3 . ? 6.959 53.505 23.422 1.00 27.70 ? 705 NAG C C6 1 HETATM 10093 C C7 . NAG U 3 . ? 1.906 55.300 27.506 1.00 23.83 ? 705 NAG C C7 1 HETATM 10094 C C8 . NAG U 3 . ? 0.844 56.336 27.900 1.00 23.88 ? 705 NAG C C8 1 HETATM 10095 N N2 . NAG U 3 . ? 2.770 55.701 26.588 1.00 24.42 ? 705 NAG C N2 1 HETATM 10096 O O3 . NAG U 3 . ? 5.151 54.819 27.891 1.00 23.64 ? 705 NAG C O3 1 HETATM 10097 O O4 . NAG U 3 . ? 7.717 54.286 26.481 1.00 24.48 ? 705 NAG C O4 1 HETATM 10098 O O5 . NAG U 3 . ? 4.648 53.949 23.959 1.00 25.36 ? 705 NAG C O5 1 HETATM 10099 O O6 . NAG U 3 . ? 6.559 52.149 23.654 1.00 27.71 ? 705 NAG C O6 1 HETATM 10100 O O7 . NAG U 3 . ? 1.976 54.210 28.053 1.00 24.85 ? 705 NAG C O7 1 HETATM 10101 C C1 . MLI V 4 . ? -6.726 75.141 17.356 1.00 49.44 ? 706 MLI C C1 1 HETATM 10102 C C2 . MLI V 4 . ? -7.073 76.468 16.653 1.00 50.26 ? 706 MLI C C2 1 HETATM 10103 C C3 . MLI V 4 . ? -7.543 73.928 16.798 1.00 48.95 ? 706 MLI C C3 1 HETATM 10104 O O6 . MLI V 4 . ? -7.804 76.427 15.651 1.00 49.24 ? 706 MLI C O6 1 HETATM 10105 O O7 . MLI V 4 . ? -6.573 77.509 17.111 1.00 49.66 ? 706 MLI C O7 1 HETATM 10106 O O8 . MLI V 4 . ? -6.887 73.156 16.068 1.00 54.00 ? 706 MLI C O8 1 HETATM 10107 O O9 . MLI V 4 . ? -8.751 73.708 17.150 1.00 38.41 ? 706 MLI C O9 1 HETATM 10108 C C1 . GOL W 5 . ? -3.112 65.888 -4.416 1.00 49.20 ? 707 GOL C C1 1 HETATM 10109 O O1 . GOL W 5 . ? -1.713 65.671 -4.700 1.00 43.27 ? 707 GOL C O1 1 HETATM 10110 C C2 . GOL W 5 . ? -3.139 66.920 -3.289 1.00 51.05 ? 707 GOL C C2 1 HETATM 10111 O O2 . GOL W 5 . ? -4.364 67.620 -3.239 1.00 52.30 ? 707 GOL C O2 1 HETATM 10112 C C3 . GOL W 5 . ? -2.898 66.264 -1.960 1.00 45.24 ? 707 GOL C C3 1 HETATM 10113 O O3 . GOL W 5 . ? -1.826 67.027 -1.465 1.00 49.75 ? 707 GOL C O3 1 HETATM 10114 O O . HOH X 6 . ? -1.409 38.292 2.514 1.00 28.40 ? 801 HOH A O 1 HETATM 10115 O O . HOH X 6 . ? -16.580 18.692 25.376 1.00 3.82 ? 802 HOH A O 1 HETATM 10116 O O . HOH X 6 . ? 12.904 24.922 7.153 1.00 13.99 ? 803 HOH A O 1 HETATM 10117 O O . HOH X 6 . ? -4.764 10.715 6.311 1.00 3.88 ? 804 HOH A O 1 HETATM 10118 O O . HOH X 6 . ? -6.246 10.249 24.594 1.00 22.24 ? 805 HOH A O 1 HETATM 10119 O O . HOH X 6 . ? 12.367 22.601 16.039 1.00 13.11 ? 806 HOH A O 1 HETATM 10120 O O . HOH X 6 . ? 10.967 18.995 0.005 0.50 15.85 ? 807 HOH A O 1 HETATM 10121 O O . HOH X 6 . ? 0.466 35.539 30.155 1.00 19.54 ? 808 HOH A O 1 HETATM 10122 O O . HOH X 6 . ? -13.134 3.428 11.962 1.00 10.69 ? 809 HOH A O 1 HETATM 10123 O O . HOH X 6 . ? -5.863 21.213 7.390 1.00 15.62 ? 810 HOH A O 1 HETATM 10124 O O . HOH X 6 . ? 4.092 34.171 34.235 1.00 10.87 ? 811 HOH A O 1 HETATM 10125 O O . HOH X 6 . ? -5.547 23.577 9.211 1.00 12.98 ? 812 HOH A O 1 HETATM 10126 O O . HOH X 6 . ? -1.948 10.685 31.460 1.00 19.99 ? 813 HOH A O 1 HETATM 10127 O O . HOH X 6 . ? 4.150 16.092 40.395 1.00 19.94 ? 814 HOH A O 1 HETATM 10128 O O . HOH X 6 . ? -5.343 33.795 29.677 1.00 12.07 ? 815 HOH A O 1 HETATM 10129 O O . HOH X 6 . ? -10.348 22.615 26.782 1.00 5.46 ? 816 HOH A O 1 HETATM 10130 O O . HOH X 6 . ? -17.895 1.788 5.206 1.00 3.88 ? 817 HOH A O 1 HETATM 10131 O O . HOH X 6 . ? -9.121 20.198 9.537 1.00 5.92 ? 818 HOH A O 1 HETATM 10132 O O . HOH X 6 . ? -15.094 1.007 3.945 1.00 9.73 ? 819 HOH A O 1 HETATM 10133 O O . HOH X 6 . ? 0.764 21.891 14.246 1.00 6.24 ? 820 HOH A O 1 HETATM 10134 O O . HOH X 6 . ? -18.768 10.272 10.278 1.00 7.21 ? 821 HOH A O 1 HETATM 10135 O O . HOH X 6 . ? -8.969 24.852 22.618 1.00 2.00 ? 822 HOH A O 1 HETATM 10136 O O . HOH X 6 . ? -13.486 17.728 29.299 1.00 3.68 ? 823 HOH A O 1 HETATM 10137 O O . HOH X 6 . ? -8.685 17.410 18.467 1.00 6.82 ? 824 HOH A O 1 HETATM 10138 O O . HOH X 6 . ? -8.660 40.010 12.691 1.00 20.66 ? 825 HOH A O 1 HETATM 10139 O O . HOH X 6 . ? -13.337 21.177 16.400 1.00 3.36 ? 826 HOH A O 1 HETATM 10140 O O . HOH X 6 . ? -13.881 20.341 30.398 1.00 9.99 ? 827 HOH A O 1 HETATM 10141 O O . HOH X 6 . ? 1.206 24.664 11.377 1.00 12.51 ? 828 HOH A O 1 HETATM 10142 O O . HOH X 6 . ? -15.509 39.659 18.748 1.00 6.26 ? 829 HOH A O 1 HETATM 10143 O O . HOH X 6 . ? -24.449 10.918 22.782 1.00 7.40 ? 830 HOH A O 1 HETATM 10144 O O . HOH X 6 . ? -19.067 34.421 13.899 1.00 18.57 ? 831 HOH A O 1 HETATM 10145 O O . HOH X 6 . ? -11.397 39.020 11.129 1.00 15.67 ? 832 HOH A O 1 HETATM 10146 O O . HOH X 6 . ? 1.719 8.396 38.180 1.00 26.76 ? 833 HOH A O 1 HETATM 10147 O O . HOH X 6 . ? -6.479 15.300 25.367 1.00 10.82 ? 834 HOH A O 1 HETATM 10148 O O . HOH X 6 . ? -28.340 15.932 23.161 1.00 16.08 ? 835 HOH A O 1 HETATM 10149 O O . HOH X 6 . ? -12.332 22.527 28.759 1.00 16.26 ? 836 HOH A O 1 HETATM 10150 O O . HOH X 6 . ? -0.318 33.826 35.338 1.00 20.05 ? 837 HOH A O 1 HETATM 10151 O O . HOH X 6 . ? -2.512 31.432 29.914 1.00 9.92 ? 838 HOH A O 1 HETATM 10152 O O . HOH X 6 . ? 4.931 20.859 34.190 1.00 15.48 ? 839 HOH A O 1 HETATM 10153 O O . HOH X 6 . ? -23.287 6.182 14.272 1.00 11.90 ? 840 HOH A O 1 HETATM 10154 O O . HOH X 6 . ? -14.168 21.917 19.411 1.00 15.08 ? 841 HOH A O 1 HETATM 10155 O O . HOH X 6 . ? -1.423 10.587 19.811 1.00 17.27 ? 842 HOH A O 1 HETATM 10156 O O . HOH X 6 . ? 16.512 21.023 10.434 1.00 14.09 ? 843 HOH A O 1 HETATM 10157 O O . HOH X 6 . ? -23.093 25.412 31.431 1.00 2.00 ? 844 HOH A O 1 HETATM 10158 O O . HOH X 6 . ? 13.746 25.319 2.216 1.00 2.00 ? 845 HOH A O 1 HETATM 10159 O O . HOH X 6 . ? -11.940 43.191 19.632 1.00 32.77 ? 846 HOH A O 1 HETATM 10160 O O . HOH X 6 . ? -17.537 36.684 7.724 1.00 5.60 ? 847 HOH A O 1 HETATM 10161 O O . HOH X 6 . ? -3.938 40.026 6.044 1.00 25.45 ? 848 HOH A O 1 HETATM 10162 O O . HOH X 6 . ? 7.077 22.846 -4.521 1.00 14.46 ? 849 HOH A O 1 HETATM 10163 O O . HOH X 6 . ? 13.168 16.554 5.702 1.00 3.47 ? 850 HOH A O 1 HETATM 10164 O O . HOH X 6 . ? -28.103 25.970 21.921 1.00 19.30 ? 851 HOH A O 1 HETATM 10165 O O . HOH X 6 . ? -28.822 23.481 23.766 1.00 21.28 ? 852 HOH A O 1 HETATM 10166 O O . HOH X 6 . ? -12.379 47.167 25.956 1.00 9.22 ? 853 HOH A O 1 HETATM 10167 O O . HOH X 6 . ? 2.370 8.923 44.039 1.00 19.01 ? 854 HOH A O 1 HETATM 10168 O O . HOH X 6 . ? 6.886 11.926 0.005 0.50 29.32 ? 855 HOH A O 1 HETATM 10169 O O . HOH X 6 . ? -9.544 8.968 17.645 1.00 24.40 ? 856 HOH A O 1 HETATM 10170 O O . HOH Y 6 . ? -64.541 61.142 9.621 1.00 26.51 ? 801 HOH B O 1 HETATM 10171 O O . HOH Y 6 . ? -56.567 37.261 18.878 1.00 24.35 ? 802 HOH B O 1 HETATM 10172 O O . HOH Y 6 . ? -43.298 51.610 32.108 1.00 18.63 ? 803 HOH B O 1 HETATM 10173 O O . HOH Y 6 . ? -51.906 48.886 18.313 1.00 12.49 ? 804 HOH B O 1 HETATM 10174 O O . HOH Y 6 . ? -49.156 47.648 23.058 1.00 7.02 ? 805 HOH B O 1 HETATM 10175 O O . HOH Y 6 . ? -33.368 40.171 27.156 1.00 24.14 ? 806 HOH B O 1 HETATM 10176 O O . HOH Y 6 . ? -60.857 28.331 26.343 1.00 27.11 ? 807 HOH B O 1 HETATM 10177 O O . HOH Y 6 . ? -52.851 29.304 37.571 1.00 42.04 ? 808 HOH B O 1 HETATM 10178 O O . HOH Y 6 . ? -55.286 33.037 16.297 1.00 30.79 ? 809 HOH B O 1 HETATM 10179 O O . HOH Y 6 . ? -53.778 27.994 19.344 1.00 40.81 ? 810 HOH B O 1 HETATM 10180 O O . HOH Y 6 . ? -39.389 25.478 0.730 1.00 33.47 ? 811 HOH B O 1 HETATM 10181 O O . HOH Y 6 . ? -42.865 24.427 27.643 1.00 14.82 ? 812 HOH B O 1 HETATM 10182 O O . HOH Y 6 . ? -49.051 32.115 33.150 1.00 28.83 ? 813 HOH B O 1 HETATM 10183 O O . HOH Y 6 . ? -48.345 29.489 24.769 1.00 33.88 ? 814 HOH B O 1 HETATM 10184 O O . HOH Y 6 . ? -38.676 13.726 24.367 1.00 37.92 ? 815 HOH B O 1 HETATM 10185 O O . HOH Y 6 . ? -61.745 42.994 22.542 1.00 25.79 ? 816 HOH B O 1 HETATM 10186 O O . HOH Y 6 . ? -61.295 22.160 29.929 1.00 29.96 ? 817 HOH B O 1 HETATM 10187 O O . HOH Y 6 . ? -68.498 33.287 19.812 1.00 34.77 ? 818 HOH B O 1 HETATM 10188 O O . HOH Y 6 . ? -64.281 29.535 21.696 1.00 41.49 ? 819 HOH B O 1 HETATM 10189 O O . HOH Y 6 . ? -52.023 40.433 6.878 1.00 13.16 ? 820 HOH B O 1 HETATM 10190 O O . HOH Y 6 . ? -49.182 40.348 24.694 1.00 3.96 ? 821 HOH B O 1 HETATM 10191 O O . HOH Y 6 . ? -52.470 37.512 5.411 1.00 23.01 ? 822 HOH B O 1 HETATM 10192 O O . HOH Y 6 . ? -43.400 48.261 38.239 1.00 24.49 ? 823 HOH B O 1 HETATM 10193 O O . HOH Y 6 . ? -70.432 52.151 14.651 1.00 23.31 ? 824 HOH B O 1 HETATM 10194 O O . HOH Y 6 . ? -62.303 41.340 4.015 1.00 11.75 ? 825 HOH B O 1 HETATM 10195 O O . HOH Y 6 . ? -32.213 43.353 21.349 1.00 16.22 ? 826 HOH B O 1 HETATM 10196 O O . HOH Y 6 . ? -60.433 20.597 14.117 1.00 17.00 ? 827 HOH B O 1 HETATM 10197 O O . HOH Y 6 . ? -49.609 53.782 30.967 1.00 20.81 ? 828 HOH B O 1 HETATM 10198 O O . HOH Y 6 . ? -50.795 35.636 7.071 1.00 15.74 ? 829 HOH B O 1 HETATM 10199 O O . HOH Y 6 . ? -51.683 45.468 26.769 1.00 13.18 ? 830 HOH B O 1 HETATM 10200 O O . HOH Y 6 . ? -58.913 18.659 5.099 1.00 22.05 ? 831 HOH B O 1 HETATM 10201 O O . HOH Y 6 . ? -36.038 38.139 30.760 1.00 16.05 ? 832 HOH B O 1 HETATM 10202 O O . HOH Y 6 . ? -54.269 41.704 16.407 1.00 20.51 ? 833 HOH B O 1 HETATM 10203 O O . HOH Y 6 . ? -55.151 31.040 12.164 1.00 5.55 ? 834 HOH B O 1 HETATM 10204 O O . HOH Y 6 . ? -41.861 54.164 25.381 1.00 27.97 ? 835 HOH B O 1 HETATM 10205 O O . HOH Y 6 . ? -58.207 48.121 14.259 1.00 2.00 ? 836 HOH B O 1 HETATM 10206 O O . HOH Y 6 . ? -45.542 24.162 30.940 1.00 13.62 ? 837 HOH B O 1 HETATM 10207 O O . HOH Y 6 . ? -41.301 36.844 38.055 1.00 14.92 ? 838 HOH B O 1 HETATM 10208 O O . HOH Y 6 . ? -41.543 30.118 27.263 1.00 10.72 ? 839 HOH B O 1 HETATM 10209 O O . HOH Y 6 . ? -52.511 36.724 24.471 1.00 47.10 ? 840 HOH B O 1 HETATM 10210 O O . HOH Y 6 . ? -31.528 27.608 29.559 1.00 23.44 ? 841 HOH B O 1 HETATM 10211 O O . HOH Y 6 . ? -55.632 53.925 8.094 1.00 10.39 ? 842 HOH B O 1 HETATM 10212 O O . HOH Y 6 . ? -35.908 18.669 15.262 1.00 28.20 ? 843 HOH B O 1 HETATM 10213 O O . HOH Y 6 . ? -47.940 38.013 20.469 1.00 6.78 ? 844 HOH B O 1 HETATM 10214 O O . HOH Y 6 . ? -33.256 31.675 31.253 1.00 28.55 ? 845 HOH B O 1 HETATM 10215 O O . HOH Y 6 . ? -52.882 29.278 8.953 1.00 15.79 ? 846 HOH B O 1 HETATM 10216 O O . HOH Y 6 . ? -46.310 22.046 31.961 1.00 11.75 ? 847 HOH B O 1 HETATM 10217 O O . HOH Y 6 . ? -58.568 59.519 15.905 1.00 20.60 ? 848 HOH B O 1 HETATM 10218 O O . HOH Y 6 . ? -43.478 47.101 40.591 1.00 18.19 ? 849 HOH B O 1 HETATM 10219 O O . HOH Y 6 . ? -48.972 43.577 14.132 1.00 2.59 ? 850 HOH B O 1 HETATM 10220 O O . HOH Y 6 . ? -64.179 51.935 9.490 1.00 10.22 ? 851 HOH B O 1 HETATM 10221 O O . HOH Y 6 . ? -47.725 20.360 8.354 1.00 17.44 ? 852 HOH B O 1 HETATM 10222 O O . HOH Y 6 . ? -54.263 22.266 7.408 1.00 34.86 ? 853 HOH B O 1 HETATM 10223 O O . HOH Y 6 . ? -48.962 60.641 26.806 1.00 20.95 ? 854 HOH B O 1 HETATM 10224 O O . HOH Y 6 . ? -45.202 36.463 18.902 1.00 29.98 ? 855 HOH B O 1 HETATM 10225 O O . HOH Y 6 . ? -63.704 38.979 29.237 1.00 22.35 ? 856 HOH B O 1 HETATM 10226 O O . HOH Y 6 . ? -33.492 51.774 14.746 1.00 36.32 ? 857 HOH B O 1 HETATM 10227 O O . HOH Y 6 . ? -31.567 24.042 21.305 1.00 15.99 ? 858 HOH B O 1 HETATM 10228 O O . HOH Y 6 . ? -45.738 29.111 27.885 1.00 9.64 ? 859 HOH B O 1 HETATM 10229 O O . HOH Y 6 . ? -63.321 57.324 2.868 1.00 10.92 ? 860 HOH B O 1 HETATM 10230 O O . HOH Y 6 . ? -30.605 51.147 22.075 1.00 27.60 ? 861 HOH B O 1 HETATM 10231 O O . HOH Y 6 . ? -63.472 18.209 20.143 1.00 41.34 ? 862 HOH B O 1 HETATM 10232 O O . HOH Y 6 . ? -63.922 51.547 21.499 1.00 25.28 ? 863 HOH B O 1 HETATM 10233 O O . HOH Y 6 . ? -61.060 53.607 27.556 1.00 42.05 ? 864 HOH B O 1 HETATM 10234 O O . HOH Y 6 . ? -34.917 30.048 10.608 1.00 23.74 ? 865 HOH B O 1 HETATM 10235 O O . HOH Y 6 . ? -36.421 26.717 31.785 1.00 38.37 ? 866 HOH B O 1 HETATM 10236 O O . HOH Y 6 . ? -40.090 49.897 35.688 1.00 24.49 ? 867 HOH B O 1 HETATM 10237 O O . HOH Y 6 . ? -31.885 36.380 16.484 1.00 11.08 ? 868 HOH B O 1 HETATM 10238 O O . HOH Y 6 . ? -63.358 38.846 2.151 1.00 31.98 ? 869 HOH B O 1 HETATM 10239 O O . HOH Y 6 . ? -51.686 58.162 20.619 1.00 13.28 ? 870 HOH B O 1 HETATM 10240 O O . HOH Y 6 . ? -40.773 52.697 27.091 1.00 21.56 ? 871 HOH B O 1 HETATM 10241 O O . HOH Y 6 . ? -68.283 53.138 10.707 1.00 22.46 ? 872 HOH B O 1 HETATM 10242 O O . HOH Y 6 . ? -65.021 40.666 2.995 1.00 17.82 ? 873 HOH B O 1 HETATM 10243 O O . HOH Y 6 . ? -34.518 22.003 23.219 1.00 30.08 ? 874 HOH B O 1 HETATM 10244 O O . HOH Y 6 . ? -34.654 49.079 20.526 1.00 23.94 ? 875 HOH B O 1 HETATM 10245 O O . HOH Y 6 . ? -56.150 34.838 22.393 1.00 20.55 ? 876 HOH B O 1 HETATM 10246 O O . HOH Y 6 . ? -42.841 20.288 7.528 1.00 23.86 ? 877 HOH B O 1 HETATM 10247 O O . HOH Y 6 . ? -47.906 44.019 17.056 1.00 26.11 ? 878 HOH B O 1 HETATM 10248 O O . HOH Y 6 . ? -50.634 47.565 41.386 1.00 13.40 ? 879 HOH B O 1 HETATM 10249 O O . HOH Y 6 . ? -63.205 45.273 39.403 1.00 22.38 ? 880 HOH B O 1 HETATM 10250 O O . HOH Y 6 . ? -38.489 41.449 38.464 1.00 25.80 ? 881 HOH B O 1 HETATM 10251 O O . HOH Y 6 . ? -69.296 23.721 17.308 1.00 36.73 ? 882 HOH B O 1 HETATM 10252 O O . HOH Y 6 . ? -58.883 18.106 0.001 1.00 2.67 ? 883 HOH B O 1 HETATM 10253 O O . HOH Y 6 . ? -43.450 23.243 30.502 1.00 19.45 ? 884 HOH B O 1 HETATM 10254 O O . HOH Y 6 . ? -59.457 32.726 38.888 1.00 27.38 ? 885 HOH B O 1 HETATM 10255 O O . HOH Y 6 . ? -43.739 53.643 35.396 1.00 43.32 ? 886 HOH B O 1 HETATM 10256 O O . HOH Y 6 . ? -60.819 44.965 15.942 1.00 16.64 ? 887 HOH B O 1 HETATM 10257 O O . HOH Y 6 . ? -44.691 25.657 32.479 1.00 14.06 ? 888 HOH B O 1 HETATM 10258 O O . HOH Y 6 . ? -40.233 49.924 29.131 1.00 7.19 ? 889 HOH B O 1 HETATM 10259 O O . HOH Y 6 . ? -42.204 51.947 29.440 1.00 15.03 ? 890 HOH B O 1 HETATM 10260 O O . HOH Y 6 . ? -33.488 39.272 5.490 1.00 10.81 ? 891 HOH B O 1 HETATM 10261 O O . HOH Y 6 . ? -34.654 40.805 30.924 1.00 27.58 ? 892 HOH B O 1 HETATM 10262 O O . HOH Y 6 . ? -37.767 26.091 3.141 1.00 35.28 ? 893 HOH B O 1 HETATM 10263 O O . HOH Y 6 . ? -57.743 40.479 23.132 1.00 16.90 ? 894 HOH B O 1 HETATM 10264 O O . HOH Y 6 . ? -45.552 54.283 27.327 1.00 30.41 ? 895 HOH B O 1 HETATM 10265 O O . HOH Y 6 . ? -66.296 22.991 3.549 1.00 5.38 ? 896 HOH B O 1 HETATM 10266 O O . HOH Y 6 . ? -51.013 49.551 43.231 1.00 26.92 ? 897 HOH B O 1 HETATM 10267 O O . HOH Y 6 . ? -48.968 59.860 29.502 1.00 26.12 ? 898 HOH B O 1 HETATM 10268 O O . HOH Y 6 . ? -26.678 29.817 23.681 1.00 11.41 ? 899 HOH B O 1 HETATM 10269 O O . HOH Y 6 . ? -33.620 44.995 25.636 1.00 20.28 ? 900 HOH B O 1 HETATM 10270 O O . HOH Y 6 . ? -32.291 30.603 33.328 1.00 26.14 ? 901 HOH B O 1 HETATM 10271 O O . HOH Y 6 . ? -43.032 27.077 31.526 1.00 23.69 ? 902 HOH B O 1 HETATM 10272 O O . HOH Y 6 . ? -71.444 38.621 -2.316 1.00 21.43 ? 903 HOH B O 1 HETATM 10273 O O . HOH Y 6 . ? -54.726 62.114 13.064 1.00 25.73 ? 904 HOH B O 1 HETATM 10274 O O . HOH Y 6 . ? -57.413 25.589 -7.129 1.00 15.74 ? 905 HOH B O 1 HETATM 10275 O O . HOH Y 6 . ? -59.543 17.551 2.116 1.00 18.00 ? 906 HOH B O 1 HETATM 10276 O O . HOH Y 6 . ? -60.935 49.943 39.046 1.00 6.22 ? 907 HOH B O 1 HETATM 10277 O O . HOH Y 6 . ? -64.028 47.340 11.655 1.00 18.64 ? 908 HOH B O 1 HETATM 10278 O O . HOH Y 6 . ? -31.907 26.075 31.208 1.00 21.65 ? 909 HOH B O 1 HETATM 10279 O O . HOH Y 6 . ? -43.438 44.504 42.907 1.00 36.07 ? 910 HOH B O 1 HETATM 10280 O O . HOH Y 6 . ? -57.600 27.857 19.135 1.00 22.96 ? 911 HOH B O 1 HETATM 10281 O O . HOH Y 6 . ? -60.678 63.549 16.710 1.00 23.79 ? 912 HOH B O 1 HETATM 10282 O O . HOH Y 6 . ? -27.620 27.662 20.128 1.00 25.04 ? 913 HOH B O 1 HETATM 10283 O O . HOH Y 6 . ? -34.999 26.817 34.034 1.00 28.09 ? 914 HOH B O 1 HETATM 10284 O O . HOH Y 6 . ? -45.952 36.298 42.030 1.00 15.05 ? 915 HOH B O 1 HETATM 10285 O O . HOH Y 6 . ? -30.713 36.949 29.654 1.00 32.59 ? 916 HOH B O 1 HETATM 10286 O O . HOH Y 6 . ? -58.121 62.472 16.377 1.00 32.25 ? 917 HOH B O 1 HETATM 10287 O O . HOH Y 6 . ? -39.083 12.992 27.921 1.00 35.22 ? 918 HOH B O 1 HETATM 10288 O O . HOH Y 6 . ? -64.397 49.216 42.579 1.00 27.70 ? 919 HOH B O 1 HETATM 10289 O O . HOH Y 6 . ? -70.828 19.737 19.725 1.00 40.01 ? 920 HOH B O 1 HETATM 10290 O O . HOH Y 6 . ? -60.906 36.999 39.771 1.00 34.73 ? 921 HOH B O 1 HETATM 10291 O O . HOH Y 6 . ? -41.373 42.555 43.689 1.00 31.22 ? 922 HOH B O 1 HETATM 10292 O O . HOH Y 6 . ? -63.376 40.650 40.507 1.00 22.73 ? 923 HOH B O 1 HETATM 10293 O O . HOH Y 6 . ? -43.636 35.001 42.302 1.00 30.97 ? 924 HOH B O 1 HETATM 10294 O O . HOH Y 6 . ? -45.412 33.492 43.581 1.00 26.62 ? 925 HOH B O 1 HETATM 10295 O O . HOH Y 6 . ? -49.617 28.514 44.032 1.00 34.16 ? 926 HOH B O 1 HETATM 10296 O O . HOH Z 6 . ? -2.537 73.476 32.169 1.00 17.40 ? 801 HOH C O 1 HETATM 10297 O O . HOH Z 6 . ? -3.541 69.125 18.677 1.00 14.87 ? 802 HOH C O 1 HETATM 10298 O O . HOH Z 6 . ? -32.827 65.277 4.913 1.00 18.70 ? 803 HOH C O 1 HETATM 10299 O O . HOH Z 6 . ? -7.928 61.521 27.561 1.00 12.65 ? 804 HOH C O 1 HETATM 10300 O O . HOH Z 6 . ? -23.763 75.993 -4.135 1.00 34.54 ? 805 HOH C O 1 HETATM 10301 O O . HOH Z 6 . ? -4.333 57.507 0.525 1.00 16.87 ? 806 HOH C O 1 HETATM 10302 O O . HOH Z 6 . ? -21.878 85.158 2.415 1.00 9.10 ? 807 HOH C O 1 HETATM 10303 O O . HOH Z 6 . ? -7.075 75.923 8.498 1.00 21.75 ? 808 HOH C O 1 HETATM 10304 O O . HOH Z 6 . ? -32.797 62.622 8.927 1.00 18.16 ? 809 HOH C O 1 HETATM 10305 O O . HOH Z 6 . ? 3.233 58.929 24.947 1.00 13.29 ? 810 HOH C O 1 HETATM 10306 O O . HOH Z 6 . ? -18.717 47.158 12.858 1.00 30.07 ? 811 HOH C O 1 HETATM 10307 O O . HOH Z 6 . ? -28.783 82.408 10.997 1.00 21.12 ? 812 HOH C O 1 HETATM 10308 O O . HOH Z 6 . ? 7.291 68.860 7.668 1.00 3.80 ? 813 HOH C O 1 HETATM 10309 O O . HOH Z 6 . ? -25.697 84.756 18.309 1.00 22.46 ? 814 HOH C O 1 HETATM 10310 O O . HOH Z 6 . ? -31.535 71.599 36.425 1.00 19.78 ? 815 HOH C O 1 HETATM 10311 O O . HOH Z 6 . ? -28.304 83.944 9.323 1.00 15.96 ? 816 HOH C O 1 HETATM 10312 O O . HOH Z 6 . ? -10.610 69.014 20.648 1.00 22.17 ? 817 HOH C O 1 HETATM 10313 O O . HOH Z 6 . ? -14.482 65.195 29.014 1.00 12.54 ? 818 HOH C O 1 HETATM 10314 O O . HOH Z 6 . ? -14.940 80.491 26.198 1.00 27.96 ? 819 HOH C O 1 HETATM 10315 O O . HOH Z 6 . ? -19.443 74.811 16.370 1.00 15.44 ? 820 HOH C O 1 HETATM 10316 O O . HOH Z 6 . ? -14.585 77.927 32.990 1.00 13.08 ? 821 HOH C O 1 HETATM 10317 O O . HOH Z 6 . ? -3.155 63.151 3.922 1.00 34.97 ? 822 HOH C O 1 HETATM 10318 O O . HOH Z 6 . ? -22.910 63.153 1.122 1.00 30.03 ? 823 HOH C O 1 HETATM 10319 O O . HOH Z 6 . ? -15.880 69.705 9.347 1.00 19.06 ? 824 HOH C O 1 HETATM 10320 O O . HOH Z 6 . ? -26.543 63.525 31.548 1.00 25.82 ? 825 HOH C O 1 HETATM 10321 O O . HOH Z 6 . ? -31.609 72.213 0.824 1.00 19.37 ? 826 HOH C O 1 HETATM 10322 O O . HOH Z 6 . ? -6.993 50.962 13.576 1.00 22.46 ? 827 HOH C O 1 HETATM 10323 O O . HOH Z 6 . ? 12.664 75.001 6.981 1.00 23.82 ? 828 HOH C O 1 HETATM 10324 O O . HOH Z 6 . ? -21.647 74.184 13.661 1.00 14.97 ? 829 HOH C O 1 HETATM 10325 O O . HOH Z 6 . ? 0.397 63.956 12.461 1.00 21.62 ? 830 HOH C O 1 HETATM 10326 O O . HOH Z 6 . ? -15.788 85.848 6.152 1.00 13.24 ? 831 HOH C O 1 HETATM 10327 O O . HOH Z 6 . ? -31.060 53.707 21.055 1.00 22.37 ? 832 HOH C O 1 HETATM 10328 O O . HOH Z 6 . ? 0.788 66.625 -4.249 1.00 28.20 ? 833 HOH C O 1 HETATM 10329 O O . HOH Z 6 . ? 4.479 67.610 2.353 1.00 7.00 ? 834 HOH C O 1 HETATM 10330 O O . HOH Z 6 . ? -16.820 85.732 30.732 1.00 29.21 ? 835 HOH C O 1 HETATM 10331 O O . HOH Z 6 . ? -28.897 63.817 -2.459 1.00 29.98 ? 836 HOH C O 1 HETATM 10332 O O . HOH Z 6 . ? -19.242 57.698 0.170 1.00 25.10 ? 837 HOH C O 1 HETATM 10333 O O . HOH Z 6 . ? -8.526 64.817 31.523 1.00 18.75 ? 838 HOH C O 1 HETATM 10334 O O . HOH Z 6 . ? -14.448 71.266 -5.823 1.00 34.26 ? 839 HOH C O 1 HETATM 10335 O O . HOH Z 6 . ? -0.636 76.740 33.254 1.00 25.25 ? 840 HOH C O 1 HETATM 10336 O O . HOH Z 6 . ? -16.590 77.139 8.094 1.00 25.39 ? 841 HOH C O 1 HETATM 10337 O O . HOH Z 6 . ? -26.303 52.043 14.249 1.00 20.70 ? 842 HOH C O 1 HETATM 10338 O O . HOH Z 6 . ? -26.452 51.846 20.926 1.00 10.84 ? 843 HOH C O 1 HETATM 10339 O O . HOH Z 6 . ? -17.102 65.104 24.782 1.00 7.30 ? 844 HOH C O 1 HETATM 10340 O O . HOH Z 6 . ? 6.506 62.226 16.335 1.00 26.05 ? 845 HOH C O 1 HETATM 10341 O O . HOH Z 6 . ? -34.730 75.568 13.246 1.00 28.05 ? 846 HOH C O 1 HETATM 10342 O O . HOH Z 6 . ? -29.014 68.103 37.691 1.00 21.56 ? 847 HOH C O 1 HETATM 10343 O O . HOH Z 6 . ? -13.041 67.178 11.839 1.00 3.68 ? 848 HOH C O 1 HETATM 10344 O O . HOH Z 6 . ? -11.702 63.253 18.574 1.00 15.95 ? 849 HOH C O 1 HETATM 10345 O O . HOH Z 6 . ? -37.590 69.200 13.880 1.00 31.91 ? 850 HOH C O 1 HETATM 10346 O O . HOH Z 6 . ? -22.096 71.791 -3.409 1.00 31.97 ? 851 HOH C O 1 HETATM 10347 O O . HOH Z 6 . ? -5.902 74.944 26.564 1.00 25.16 ? 852 HOH C O 1 HETATM 10348 O O . HOH Z 6 . ? -35.911 55.378 23.838 1.00 27.64 ? 853 HOH C O 1 HETATM 10349 O O . HOH Z 6 . ? -38.370 72.213 16.903 1.00 30.81 ? 854 HOH C O 1 HETATM 10350 O O . HOH Z 6 . ? -8.453 78.597 21.902 1.00 14.09 ? 855 HOH C O 1 HETATM 10351 O O . HOH Z 6 . ? 0.583 52.805 25.448 1.00 21.34 ? 856 HOH C O 1 HETATM 10352 O O . HOH Z 6 . ? -1.492 61.963 2.709 1.00 22.39 ? 857 HOH C O 1 HETATM 10353 O O . HOH Z 6 . ? -44.881 61.744 23.640 1.00 32.50 ? 858 HOH C O 1 HETATM 10354 O O . HOH Z 6 . ? -12.942 76.112 27.868 1.00 27.87 ? 859 HOH C O 1 HETATM 10355 O O . HOH Z 6 . ? -11.740 61.903 22.049 1.00 24.56 ? 860 HOH C O 1 HETATM 10356 O O . HOH Z 6 . ? 1.546 74.064 14.538 1.00 20.23 ? 861 HOH C O 1 HETATM 10357 O O . HOH Z 6 . ? -17.553 68.587 11.444 1.00 11.06 ? 862 HOH C O 1 HETATM 10358 O O . HOH Z 6 . ? -42.112 69.248 17.432 1.00 24.56 ? 863 HOH C O 1 HETATM 10359 O O . HOH Z 6 . ? 4.414 58.002 3.232 1.00 16.01 ? 864 HOH C O 1 HETATM 10360 O O . HOH Z 6 . ? -31.734 76.812 0.288 1.00 41.80 ? 865 HOH C O 1 HETATM 10361 O O . HOH Z 6 . ? -13.474 63.347 31.153 1.00 11.94 ? 866 HOH C O 1 HETATM 10362 O O . HOH Z 6 . ? -9.709 78.556 33.711 1.00 30.24 ? 867 HOH C O 1 HETATM 10363 O O . HOH Z 6 . ? -14.168 84.487 2.625 1.00 25.56 ? 868 HOH C O 1 HETATM 10364 O O . HOH Z 6 . ? -26.080 69.882 -4.624 1.00 32.72 ? 869 HOH C O 1 HETATM 10365 O O . HOH Z 6 . ? -28.404 80.056 0.055 1.00 25.77 ? 870 HOH C O 1 HETATM 10366 O O . HOH Z 6 . ? -20.518 78.852 36.394 1.00 24.10 ? 871 HOH C O 1 HETATM 10367 O O . HOH Z 6 . ? -28.731 84.379 4.255 1.00 11.43 ? 872 HOH C O 1 HETATM 10368 O O . HOH Z 6 . ? -24.180 66.926 -2.459 1.00 33.39 ? 873 HOH C O 1 HETATM 10369 O O . HOH Z 6 . ? -0.011 58.243 5.595 1.00 25.41 ? 874 HOH C O 1 HETATM 10370 O O . HOH Z 6 . ? -12.793 69.616 -6.826 1.00 34.39 ? 875 HOH C O 1 HETATM 10371 O O . HOH Z 6 . ? 2.121 68.618 51.533 1.00 19.74 ? 876 HOH C O 1 HETATM 10372 O O . HOH Z 6 . ? 7.663 66.680 -1.945 1.00 26.50 ? 877 HOH C O 1 HETATM 10373 O O . HOH Z 6 . ? -28.649 84.608 6.823 1.00 21.69 ? 878 HOH C O 1 HETATM 10374 O O . HOH Z 6 . ? -33.044 60.313 8.865 1.00 25.89 ? 879 HOH C O 1 HETATM 10375 O O . HOH Z 6 . ? -23.007 51.638 9.872 1.00 15.85 ? 880 HOH C O 1 HETATM 10376 O O . HOH Z 6 . ? -10.448 52.643 33.679 1.00 7.24 ? 881 HOH C O 1 HETATM 10377 O O . HOH Z 6 . ? -32.500 66.848 3.386 1.00 22.81 ? 882 HOH C O 1 HETATM 10378 O O . HOH Z 6 . ? -1.482 43.612 10.473 1.00 28.89 ? 883 HOH C O 1 HETATM 10379 O O . HOH Z 6 . ? -25.318 57.250 4.045 1.00 21.75 ? 884 HOH C O 1 HETATM 10380 O O . HOH Z 6 . ? 4.869 66.943 -0.941 1.00 21.97 ? 885 HOH C O 1 HETATM 10381 O O . HOH Z 6 . ? -11.653 81.700 -2.400 1.00 22.00 ? 886 HOH C O 1 HETATM 10382 O O . HOH Z 6 . ? -2.448 72.223 19.684 1.00 25.85 ? 887 HOH C O 1 HETATM 10383 O O . HOH Z 6 . ? -36.464 78.381 14.492 1.00 37.62 ? 888 HOH C O 1 HETATM 10384 O O . HOH Z 6 . ? -33.556 72.144 2.587 1.00 17.50 ? 889 HOH C O 1 HETATM 10385 O O . HOH Z 6 . ? -26.308 89.283 12.717 1.00 6.92 ? 890 HOH C O 1 HETATM 10386 O O . HOH Z 6 . ? -27.659 88.142 11.347 1.00 27.67 ? 891 HOH C O 1 HETATM 10387 O O . HOH Z 6 . ? -9.707 60.411 13.220 1.00 27.00 ? 892 HOH C O 1 HETATM 10388 O O . HOH Z 6 . ? -20.505 88.385 8.075 1.00 17.94 ? 893 HOH C O 1 HETATM 10389 O O . HOH Z 6 . ? -34.377 57.479 8.740 1.00 27.80 ? 894 HOH C O 1 HETATM 10390 O O . HOH Z 6 . ? -8.883 83.012 46.197 1.00 17.56 ? 895 HOH C O 1 HETATM 10391 O O . HOH Z 6 . ? -34.574 51.191 28.286 1.00 31.60 ? 896 HOH C O 1 HETATM 10392 O O . HOH Z 6 . ? -12.501 58.480 14.697 1.00 38.16 ? 897 HOH C O 1 HETATM 10393 O O . HOH Z 6 . ? -8.968 47.782 22.844 1.00 31.22 ? 898 HOH C O 1 HETATM 10394 O O . HOH Z 6 . ? 6.092 61.865 -2.655 1.00 26.45 ? 899 HOH C O 1 HETATM 10395 O O . HOH Z 6 . ? -37.142 59.580 11.861 1.00 40.02 ? 900 HOH C O 1 HETATM 10396 O O . HOH Z 6 . ? -37.272 62.249 12.503 1.00 17.81 ? 901 HOH C O 1 HETATM 10397 O O . HOH Z 6 . ? -5.544 48.660 26.238 1.00 19.25 ? 902 HOH C O 1 HETATM 10398 O O . HOH Z 6 . ? 4.287 69.160 0.063 1.00 27.33 ? 903 HOH C O 1 HETATM 10399 O O . HOH Z 6 . ? -19.871 84.006 0.928 1.00 14.72 ? 904 HOH C O 1 HETATM 10400 O O . HOH Z 6 . ? -31.189 55.566 11.467 1.00 21.47 ? 905 HOH C O 1 HETATM 10401 O O . HOH Z 6 . ? 7.108 52.150 9.696 1.00 30.36 ? 906 HOH C O 1 HETATM 10402 O O . HOH Z 6 . ? -3.512 78.552 24.304 1.00 30.36 ? 907 HOH C O 1 HETATM 10403 O O . HOH Z 6 . ? -16.382 61.579 12.388 1.00 32.62 ? 908 HOH C O 1 HETATM 10404 O O . HOH Z 6 . ? -16.133 59.258 -3.029 1.00 31.59 ? 909 HOH C O 1 HETATM 10405 O O . HOH Z 6 . ? -3.717 72.455 2.480 1.00 27.41 ? 910 HOH C O 1 HETATM 10406 O O . HOH Z 6 . ? -0.429 50.348 7.817 1.00 26.82 ? 911 HOH C O 1 HETATM 10407 O O . HOH Z 6 . ? 5.508 73.282 3.327 1.00 21.46 ? 912 HOH C O 1 HETATM 10408 O O . HOH Z 6 . ? -6.090 61.775 48.353 1.00 17.03 ? 913 HOH C O 1 HETATM 10409 O O . HOH Z 6 . ? -33.263 81.909 12.457 1.00 24.38 ? 914 HOH C O 1 HETATM 10410 O O . HOH Z 6 . ? -4.482 71.126 0.602 1.00 31.81 ? 915 HOH C O 1 HETATM 10411 O O . HOH Z 6 . ? -10.578 50.577 4.470 1.00 31.45 ? 916 HOH C O 1 HETATM 10412 O O . HOH Z 6 . ? 8.572 60.780 -3.506 1.00 38.82 ? 917 HOH C O 1 HETATM 10413 O O . HOH Z 6 . ? -15.974 65.238 -4.902 1.00 34.49 ? 918 HOH C O 1 HETATM 10414 O O . HOH Z 6 . ? 4.377 63.080 -4.925 1.00 34.88 ? 919 HOH C O 1 # _database_PDB_caveat.id 1 _database_PDB_caveat.text 'NAG C 704 HAS WRONG CHIRALITY AT ATOM C1' # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 PRO 1 34 34 PRO PRO A . n A 1 2 PRO 2 35 35 PRO PRO A . n A 1 3 ALA 3 36 36 ALA ALA A . n A 1 4 ILE 4 37 37 ILE ILE A . n A 1 5 GLY 5 38 38 GLY GLY A . n A 1 6 GLN 6 39 39 GLN GLN A . n A 1 7 PHE 7 40 40 PHE PHE A . n A 1 8 TRP 8 41 41 TRP TRP A . n A 1 9 HIS 9 42 42 HIS HIS A . n A 1 10 VAL 10 43 43 VAL VAL A . n A 1 11 THR 11 44 44 THR THR A . n A 1 12 ASP 12 45 45 ASP ASP A . n A 1 13 LEU 13 46 46 LEU LEU A . n A 1 14 HIS 14 47 47 HIS HIS A . n A 1 15 LEU 15 48 48 LEU LEU A . n A 1 16 ASP 16 49 49 ASP ASP A . n A 1 17 PRO 17 50 50 PRO PRO A . n A 1 18 THR 18 51 51 THR THR A . n A 1 19 TYR 19 52 52 TYR TYR A . n A 1 20 HIS 20 53 53 HIS HIS A . n A 1 21 ILE 21 54 54 ILE ILE A . n A 1 22 THR 22 55 55 THR THR A . n A 1 23 ASP 23 56 56 ASP ASP A . n A 1 24 ASP 24 57 57 ASP ASP A . n A 1 25 HIS 25 58 58 HIS HIS A . n A 1 26 THR 26 59 59 THR THR A . n A 1 27 LYS 27 60 60 LYS LYS A . n A 1 28 VAL 28 61 61 VAL VAL A . n A 1 29 CYS 29 62 62 CYS CYS A . n A 1 30 ALA 30 63 63 ALA ALA A . n A 1 31 SER 31 64 64 SER SER A . n A 1 32 SER 32 65 65 SER SER A . n A 1 33 LYS 33 66 66 LYS LYS A . n A 1 34 GLY 34 67 67 GLY GLY A . n A 1 35 ALA 35 68 68 ALA ALA A . n A 1 36 ASN 36 69 69 ASN ASN A . n A 1 37 ALA 37 70 70 ALA ALA A . n A 1 38 SER 38 71 71 SER SER A . n A 1 39 ASN 39 72 72 ASN ASN A . n A 1 40 PRO 40 73 73 PRO PRO A . n A 1 41 GLY 41 74 74 GLY GLY A . n A 1 42 PRO 42 75 75 PRO PRO A . n A 1 43 PHE 43 76 76 PHE PHE A . n A 1 44 GLY 44 77 77 GLY GLY A . n A 1 45 ASP 45 78 78 ASP ASP A . n A 1 46 VAL 46 79 79 VAL VAL A . n A 1 47 LEU 47 80 80 LEU LEU A . n A 1 48 CYS 48 81 81 CYS CYS A . n A 1 49 ASP 49 82 82 ASP ASP A . n A 1 50 SER 50 83 83 SER SER A . n A 1 51 PRO 51 84 84 PRO PRO A . n A 1 52 TYR 52 85 85 TYR TYR A . n A 1 53 GLN 53 86 86 GLN GLN A . n A 1 54 LEU 54 87 87 LEU LEU A . n A 1 55 ILE 55 88 88 ILE ILE A . n A 1 56 LEU 56 89 89 LEU LEU A . n A 1 57 SER 57 90 90 SER SER A . n A 1 58 ALA 58 91 91 ALA ALA A . n A 1 59 PHE 59 92 92 PHE PHE A . n A 1 60 ASP 60 93 93 ASP ASP A . n A 1 61 PHE 61 94 94 PHE PHE A . n A 1 62 ILE 62 95 95 ILE ILE A . n A 1 63 LYS 63 96 96 LYS LYS A . n A 1 64 ASN 64 97 97 ASN ASN A . n A 1 65 SER 65 98 98 SER SER A . n A 1 66 GLY 66 99 99 GLY GLY A . n A 1 67 GLN 67 100 100 GLN GLN A . n A 1 68 GLU 68 101 101 GLU GLU A . n A 1 69 ALA 69 102 102 ALA ALA A . n A 1 70 SER 70 103 103 SER SER A . n A 1 71 PHE 71 104 104 PHE PHE A . n A 1 72 MET 72 105 105 MET MET A . n A 1 73 ILE 73 106 106 ILE ILE A . n A 1 74 TRP 74 107 107 TRP TRP A . n A 1 75 THR 75 108 108 THR THR A . n A 1 76 GLY 76 109 109 GLY GLY A . n A 1 77 ASP 77 110 110 ASP ASP A . n A 1 78 SER 78 111 111 SER SER A . n A 1 79 PRO 79 112 112 PRO PRO A . n A 1 80 PRO 80 113 113 PRO PRO A . n A 1 81 HIS 81 114 114 HIS HIS A . n A 1 82 VAL 82 115 115 VAL VAL A . n A 1 83 PRO 83 116 116 PRO PRO A . n A 1 84 VAL 84 117 117 VAL VAL A . n A 1 85 PRO 85 118 118 PRO PRO A . n A 1 86 GLU 86 119 119 GLU GLU A . n A 1 87 LEU 87 120 120 LEU LEU A . n A 1 88 SER 88 121 121 SER SER A . n A 1 89 THR 89 122 122 THR THR A . n A 1 90 ASP 90 123 123 ASP ASP A . n A 1 91 THR 91 124 124 THR THR A . n A 1 92 VAL 92 125 125 VAL VAL A . n A 1 93 ILE 93 126 126 ILE ILE A . n A 1 94 ASN 94 127 127 ASN ASN A . n A 1 95 VAL 95 128 128 VAL VAL A . n A 1 96 ILE 96 129 129 ILE ILE A . n A 1 97 THR 97 130 130 THR THR A . n A 1 98 ASN 98 131 131 ASN ASN A . n A 1 99 MET 99 132 132 MET MET A . n A 1 100 THR 100 133 133 THR THR A . n A 1 101 THR 101 134 134 THR THR A . n A 1 102 THR 102 135 135 THR THR A . n A 1 103 ILE 103 136 136 ILE ILE A . n A 1 104 GLN 104 137 137 GLN GLN A . n A 1 105 SER 105 138 138 SER SER A . n A 1 106 LEU 106 139 139 LEU LEU A . n A 1 107 PHE 107 140 140 PHE PHE A . n A 1 108 PRO 108 141 141 PRO PRO A . n A 1 109 ASN 109 142 142 ASN ASN A . n A 1 110 LEU 110 143 143 LEU LEU A . n A 1 111 GLN 111 144 144 GLN GLN A . n A 1 112 VAL 112 145 145 VAL VAL A . n A 1 113 PHE 113 146 146 PHE PHE A . n A 1 114 PRO 114 147 147 PRO PRO A . n A 1 115 ALA 115 148 148 ALA ALA A . n A 1 116 LEU 116 149 149 LEU LEU A . n A 1 117 GLY 117 150 150 GLY GLY A . n A 1 118 ASN 118 151 151 ASN ASN A . n A 1 119 HIS 119 152 152 HIS HIS A . n A 1 120 ASP 120 153 153 ASP ASP A . n A 1 121 TYR 121 154 154 TYR TYR A . n A 1 122 TRP 122 155 155 TRP TRP A . n A 1 123 PRO 123 156 156 PRO PRO A . n A 1 124 GLN 124 157 157 GLN GLN A . n A 1 125 ASP 125 158 158 ASP ASP A . n A 1 126 GLN 126 159 159 GLN GLN A . n A 1 127 LEU 127 160 160 LEU LEU A . n A 1 128 PRO 128 161 161 PRO PRO A . n A 1 129 VAL 129 162 162 VAL VAL A . n A 1 130 VAL 130 163 163 VAL VAL A . n A 1 131 THR 131 164 164 THR THR A . n A 1 132 SER 132 165 165 SER SER A . n A 1 133 LYS 133 166 166 LYS LYS A . n A 1 134 VAL 134 167 167 VAL VAL A . n A 1 135 TYR 135 168 168 TYR TYR A . n A 1 136 ASN 136 169 169 ASN ASN A . n A 1 137 ALA 137 170 170 ALA ALA A . n A 1 138 VAL 138 171 171 VAL VAL A . n A 1 139 ALA 139 172 172 ALA ALA A . n A 1 140 ASN 140 173 173 ASN ASN A . n A 1 141 LEU 141 174 174 LEU LEU A . n A 1 142 TRP 142 175 175 TRP TRP A . n A 1 143 LYS 143 176 176 LYS LYS A . n A 1 144 PRO 144 177 177 PRO PRO A . n A 1 145 TRP 145 178 178 TRP TRP A . n A 1 146 LEU 146 179 179 LEU LEU A . n A 1 147 ASP 147 180 180 ASP ASP A . n A 1 148 GLU 148 181 181 GLU GLU A . n A 1 149 GLU 149 182 182 GLU GLU A . n A 1 150 ALA 150 183 183 ALA ALA A . n A 1 151 ILE 151 184 184 ILE ILE A . n A 1 152 SER 152 185 185 SER SER A . n A 1 153 THR 153 186 186 THR THR A . n A 1 154 LEU 154 187 187 LEU LEU A . n A 1 155 ARG 155 188 188 ARG ARG A . n A 1 156 LYS 156 189 189 LYS LYS A . n A 1 157 GLY 157 190 190 GLY GLY A . n A 1 158 GLY 158 191 191 GLY GLY A . n A 1 159 PHE 159 192 192 PHE PHE A . n A 1 160 TYR 160 193 193 TYR TYR A . n A 1 161 SER 161 194 194 SER SER A . n A 1 162 GLN 162 195 195 GLN GLN A . n A 1 163 LYS 163 196 196 LYS LYS A . n A 1 164 VAL 164 197 197 VAL VAL A . n A 1 165 THR 165 198 198 THR THR A . n A 1 166 THR 166 199 199 THR THR A . n A 1 167 ASN 167 200 200 ASN ASN A . n A 1 168 PRO 168 201 201 PRO PRO A . n A 1 169 ASN 169 202 202 ASN ASN A . n A 1 170 LEU 170 203 203 LEU LEU A . n A 1 171 ARG 171 204 204 ARG ARG A . n A 1 172 ILE 172 205 205 ILE ILE A . n A 1 173 ILE 173 206 206 ILE ILE A . n A 1 174 SER 174 207 207 SER SER A . n A 1 175 LEU 175 208 208 LEU LEU A . n A 1 176 ASN 176 209 209 ASN ASN A . n A 1 177 THR 177 210 210 THR THR A . n A 1 178 ASN 178 211 211 ASN ASN A . n A 1 179 LEU 179 212 212 LEU LEU A . n A 1 180 TYR 180 213 213 TYR TYR A . n A 1 181 TYR 181 214 214 TYR TYR A . n A 1 182 GLY 182 215 215 GLY GLY A . n A 1 183 PRO 183 216 216 PRO PRO A . n A 1 184 ASN 184 217 217 ASN ASN A . n A 1 185 ILE 185 218 218 ILE ILE A . n A 1 186 MET 186 219 219 MET MET A . n A 1 187 THR 187 220 220 THR THR A . n A 1 188 LEU 188 221 221 LEU LEU A . n A 1 189 ASN 189 222 222 ASN ASN A . n A 1 190 LYS 190 223 223 LYS LYS A . n A 1 191 THR 191 224 224 THR THR A . n A 1 192 ASP 192 225 225 ASP ASP A . n A 1 193 PRO 193 226 226 PRO PRO A . n A 1 194 ALA 194 227 227 ALA ALA A . n A 1 195 ASN 195 228 228 ASN ASN A . n A 1 196 GLN 196 229 229 GLN GLN A . n A 1 197 PHE 197 230 230 PHE PHE A . n A 1 198 GLU 198 231 231 GLU GLU A . n A 1 199 TRP 199 232 232 TRP TRP A . n A 1 200 LEU 200 233 233 LEU LEU A . n A 1 201 GLU 201 234 234 GLU GLU A . n A 1 202 SER 202 235 235 SER SER A . n A 1 203 THR 203 236 236 THR THR A . n A 1 204 LEU 204 237 237 LEU LEU A . n A 1 205 ASN 205 238 238 ASN ASN A . n A 1 206 ASN 206 239 239 ASN ASN A . n A 1 207 SER 207 240 240 SER SER A . n A 1 208 GLN 208 241 241 GLN GLN A . n A 1 209 GLN 209 242 242 GLN GLN A . n A 1 210 ASN 210 243 243 ASN ASN A . n A 1 211 LYS 211 244 244 LYS LYS A . n A 1 212 GLU 212 245 245 GLU GLU A . n A 1 213 LYS 213 246 246 LYS LYS A . n A 1 214 VAL 214 247 247 VAL VAL A . n A 1 215 TYR 215 248 248 TYR TYR A . n A 1 216 ILE 216 249 249 ILE ILE A . n A 1 217 ILE 217 250 250 ILE ILE A . n A 1 218 ALA 218 251 251 ALA ALA A . n A 1 219 HIS 219 252 252 HIS HIS A . n A 1 220 VAL 220 253 253 VAL VAL A . n A 1 221 PRO 221 254 254 PRO PRO A . n A 1 222 VAL 222 255 255 VAL VAL A . n A 1 223 GLY 223 256 256 GLY GLY A . n A 1 224 TYR 224 257 257 TYR TYR A . n A 1 225 LEU 225 258 258 LEU LEU A . n A 1 226 PRO 226 259 259 PRO PRO A . n A 1 227 SER 227 260 260 SER SER A . n A 1 228 SER 228 261 261 SER SER A . n A 1 229 GLN 229 262 262 GLN GLN A . n A 1 230 ASN 230 263 263 ASN ASN A . n A 1 231 ILE 231 264 264 ILE ILE A . n A 1 232 THR 232 265 265 THR THR A . n A 1 233 ALA 233 266 266 ALA ALA A . n A 1 234 MET 234 267 267 MET MET A . n A 1 235 ARG 235 268 268 ARG ARG A . n A 1 236 GLU 236 269 269 GLU GLU A . n A 1 237 TYR 237 270 270 TYR TYR A . n A 1 238 TYR 238 271 271 TYR TYR A . n A 1 239 ASN 239 272 272 ASN ASN A . n A 1 240 GLU 240 273 273 GLU GLU A . n A 1 241 LYS 241 274 274 LYS LYS A . n A 1 242 LEU 242 275 275 LEU LEU A . n A 1 243 ILE 243 276 276 ILE ILE A . n A 1 244 ASP 244 277 277 ASP ASP A . n A 1 245 ILE 245 278 278 ILE ILE A . n A 1 246 PHE 246 279 279 PHE PHE A . n A 1 247 GLN 247 280 280 GLN GLN A . n A 1 248 LYS 248 281 281 LYS LYS A . n A 1 249 TYR 249 282 282 TYR TYR A . n A 1 250 SER 250 283 283 SER SER A . n A 1 251 ASP 251 284 284 ASP ASP A . n A 1 252 VAL 252 285 285 VAL VAL A . n A 1 253 ILE 253 286 286 ILE ILE A . n A 1 254 ALA 254 287 287 ALA ALA A . n A 1 255 GLY 255 288 288 GLY GLY A . n A 1 256 GLN 256 289 289 GLN GLN A . n A 1 257 PHE 257 290 290 PHE PHE A . n A 1 258 TYR 258 291 291 TYR TYR A . n A 1 259 GLY 259 292 292 GLY GLY A . n A 1 260 HIS 260 293 293 HIS HIS A . n A 1 261 THR 261 294 294 THR THR A . n A 1 262 HIS 262 295 295 HIS HIS A . n A 1 263 ARG 263 296 296 ARG ARG A . n A 1 264 ASP 264 297 297 ASP ASP A . n A 1 265 SER 265 298 298 SER SER A . n A 1 266 ILE 266 299 299 ILE ILE A . n A 1 267 MET 267 300 300 MET MET A . n A 1 268 VAL 268 301 301 VAL VAL A . n A 1 269 LEU 269 302 302 LEU LEU A . n A 1 270 SER 270 303 303 SER SER A . n A 1 271 ASP 271 304 304 ASP ASP A . n A 1 272 LYS 272 305 305 LYS LYS A . n A 1 273 LYS 273 306 306 LYS LYS A . n A 1 274 GLY 274 307 307 GLY GLY A . n A 1 275 SER 275 308 308 SER SER A . n A 1 276 PRO 276 309 309 PRO PRO A . n A 1 277 VAL 277 310 310 VAL VAL A . n A 1 278 ASN 278 311 311 ASN ASN A . n A 1 279 SER 279 312 312 SER SER A . n A 1 280 LEU 280 313 313 LEU LEU A . n A 1 281 PHE 281 314 314 PHE PHE A . n A 1 282 VAL 282 315 315 VAL VAL A . n A 1 283 ALA 283 316 316 ALA ALA A . n A 1 284 PRO 284 317 317 PRO PRO A . n A 1 285 ALA 285 318 318 ALA ALA A . n A 1 286 VAL 286 319 319 VAL VAL A . n A 1 287 THR 287 320 320 THR THR A . n A 1 288 PRO 288 321 321 PRO PRO A . n A 1 289 VAL 289 322 322 VAL VAL A . n A 1 290 LYS 290 323 323 LYS LYS A . n A 1 291 SER 291 324 324 SER SER A . n A 1 292 VAL 292 325 325 VAL VAL A . n A 1 293 LEU 293 326 326 LEU LEU A . n A 1 294 GLU 294 327 327 GLU GLU A . n A 1 295 LYS 295 328 328 LYS LYS A . n A 1 296 GLN 296 329 329 GLN GLN A . n A 1 297 THR 297 330 330 THR THR A . n A 1 298 ASN 298 331 331 ASN ASN A . n A 1 299 ASN 299 332 332 ASN ASN A . n A 1 300 PRO 300 333 333 PRO PRO A . n A 1 301 GLY 301 334 334 GLY GLY A . n A 1 302 ILE 302 335 335 ILE ILE A . n A 1 303 ARG 303 336 336 ARG ARG A . n A 1 304 LEU 304 337 337 LEU LEU A . n A 1 305 PHE 305 338 338 PHE PHE A . n A 1 306 GLN 306 339 339 GLN GLN A . n A 1 307 TYR 307 340 340 TYR TYR A . n A 1 308 ASP 308 341 341 ASP ASP A . n A 1 309 PRO 309 342 342 PRO PRO A . n A 1 310 ARG 310 343 343 ARG ARG A . n A 1 311 ASP 311 344 344 ASP ASP A . n A 1 312 TYR 312 345 345 TYR TYR A . n A 1 313 LYS 313 346 346 LYS LYS A . n A 1 314 LEU 314 347 347 LEU LEU A . n A 1 315 LEU 315 348 348 LEU LEU A . n A 1 316 ASP 316 349 349 ASP ASP A . n A 1 317 MET 317 350 350 MET MET A . n A 1 318 LEU 318 351 351 LEU LEU A . n A 1 319 GLN 319 352 352 GLN GLN A . n A 1 320 TYR 320 353 353 TYR TYR A . n A 1 321 TYR 321 354 354 TYR TYR A . n A 1 322 LEU 322 355 355 LEU LEU A . n A 1 323 ASN 323 356 356 ASN ASN A . n A 1 324 LEU 324 357 357 LEU LEU A . n A 1 325 THR 325 358 358 THR THR A . n A 1 326 GLU 326 359 359 GLU GLU A . n A 1 327 ALA 327 360 360 ALA ALA A . n A 1 328 ASN 328 361 361 ASN ASN A . n A 1 329 LEU 329 362 362 LEU LEU A . n A 1 330 LYS 330 363 363 LYS LYS A . n A 1 331 GLY 331 364 364 GLY GLY A . n A 1 332 GLU 332 365 365 GLU GLU A . n A 1 333 SER 333 366 366 SER SER A . n A 1 334 ILE 334 367 367 ILE ILE A . n A 1 335 TRP 335 368 368 TRP TRP A . n A 1 336 LYS 336 369 369 LYS LYS A . n A 1 337 LEU 337 370 370 LEU LEU A . n A 1 338 GLU 338 371 371 GLU GLU A . n A 1 339 TYR 339 372 372 TYR TYR A . n A 1 340 ILE 340 373 373 ILE ILE A . n A 1 341 LEU 341 374 374 LEU LEU A . n A 1 342 THR 342 375 375 THR THR A . n A 1 343 GLN 343 376 376 GLN GLN A . n A 1 344 THR 344 377 377 THR THR A . n A 1 345 TYR 345 378 378 TYR TYR A . n A 1 346 ASP 346 379 379 ASP ASP A . n A 1 347 ILE 347 380 380 ILE ILE A . n A 1 348 GLU 348 381 381 GLU GLU A . n A 1 349 ASP 349 382 382 ASP ASP A . n A 1 350 LEU 350 383 383 LEU LEU A . n A 1 351 GLN 351 384 384 GLN GLN A . n A 1 352 PRO 352 385 385 PRO PRO A . n A 1 353 GLU 353 386 386 GLU GLU A . n A 1 354 SER 354 387 387 SER SER A . n A 1 355 LEU 355 388 388 LEU LEU A . n A 1 356 TYR 356 389 389 TYR TYR A . n A 1 357 GLY 357 390 390 GLY GLY A . n A 1 358 LEU 358 391 391 LEU LEU A . n A 1 359 ALA 359 392 392 ALA ALA A . n A 1 360 LYS 360 393 393 LYS LYS A . n A 1 361 GLN 361 394 394 GLN GLN A . n A 1 362 PHE 362 395 395 PHE PHE A . n A 1 363 THR 363 396 396 THR THR A . n A 1 364 ILE 364 397 397 ILE ILE A . n A 1 365 LEU 365 398 398 LEU LEU A . n A 1 366 ASP 366 399 399 ASP ASP A . n A 1 367 SER 367 400 400 SER SER A . n A 1 368 LYS 368 401 401 LYS LYS A . n A 1 369 GLN 369 402 402 GLN GLN A . n A 1 370 PHE 370 403 403 PHE PHE A . n A 1 371 ILE 371 404 404 ILE ILE A . n A 1 372 LYS 372 405 405 LYS LYS A . n A 1 373 TYR 373 406 406 TYR TYR A . n A 1 374 TYR 374 407 407 TYR TYR A . n A 1 375 ASN 375 408 408 ASN ASN A . n A 1 376 TYR 376 409 409 TYR TYR A . n A 1 377 PHE 377 410 410 PHE PHE A . n A 1 378 PHE 378 411 411 PHE PHE A . n A 1 379 VAL 379 412 412 VAL VAL A . n A 1 380 SER 380 413 413 SER SER A . n A 1 381 TYR 381 414 414 TYR TYR A . n A 1 382 ASP 382 415 415 ASP ASP A . n A 1 383 SER 383 416 416 SER SER A . n A 1 384 SER 384 417 417 SER SER A . n A 1 385 VAL 385 418 418 VAL VAL A . n A 1 386 THR 386 419 419 THR THR A . n A 1 387 CYS 387 420 420 CYS CYS A . n A 1 388 ASP 388 421 421 ASP ASP A . n A 1 389 LYS 389 422 422 LYS LYS A . n A 1 390 THR 390 423 423 THR THR A . n A 1 391 CYS 391 424 424 CYS CYS A . n A 1 392 LYS 392 425 425 LYS LYS A . n A 1 393 ALA 393 426 426 ALA ALA A . n A 1 394 PHE 394 427 427 PHE PHE A . n A 1 395 GLN 395 428 428 GLN GLN A . n A 1 396 ILE 396 429 429 ILE ILE A . n A 1 397 CYS 397 430 430 CYS CYS A . n A 1 398 ALA 398 431 431 ALA ALA A . n A 1 399 ILE 399 432 432 ILE ILE A . n A 1 400 MET 400 433 433 MET MET A . n A 1 401 ASN 401 434 434 ASN ASN A . n A 1 402 LEU 402 435 435 LEU LEU A . n A 1 403 ASP 403 436 436 ASP ASP A . n A 1 404 ASN 404 437 437 ASN ASN A . n A 1 405 ILE 405 438 438 ILE ILE A . n A 1 406 SER 406 439 439 SER SER A . n A 1 407 TYR 407 440 440 TYR TYR A . n A 1 408 ALA 408 441 441 ALA ALA A . n A 1 409 ASP 409 442 442 ASP ASP A . n A 1 410 CYS 410 443 443 CYS CYS A . n B 1 1 PRO 1 34 34 PRO PRO B . n B 1 2 PRO 2 35 35 PRO PRO B . n B 1 3 ALA 3 36 36 ALA ALA B . n B 1 4 ILE 4 37 37 ILE ILE B . n B 1 5 GLY 5 38 38 GLY GLY B . n B 1 6 GLN 6 39 39 GLN GLN B . n B 1 7 PHE 7 40 40 PHE PHE B . n B 1 8 TRP 8 41 41 TRP TRP B . n B 1 9 HIS 9 42 42 HIS HIS B . n B 1 10 VAL 10 43 43 VAL VAL B . n B 1 11 THR 11 44 44 THR THR B . n B 1 12 ASP 12 45 45 ASP ASP B . n B 1 13 LEU 13 46 46 LEU LEU B . n B 1 14 HIS 14 47 47 HIS HIS B . n B 1 15 LEU 15 48 48 LEU LEU B . n B 1 16 ASP 16 49 49 ASP ASP B . n B 1 17 PRO 17 50 50 PRO PRO B . n B 1 18 THR 18 51 51 THR THR B . n B 1 19 TYR 19 52 52 TYR TYR B . n B 1 20 HIS 20 53 53 HIS HIS B . n B 1 21 ILE 21 54 54 ILE ILE B . n B 1 22 THR 22 55 55 THR THR B . n B 1 23 ASP 23 56 56 ASP ASP B . n B 1 24 ASP 24 57 57 ASP ASP B . n B 1 25 HIS 25 58 58 HIS HIS B . n B 1 26 THR 26 59 59 THR THR B . n B 1 27 LYS 27 60 60 LYS LYS B . n B 1 28 VAL 28 61 61 VAL VAL B . n B 1 29 CYS 29 62 62 CYS CYS B . n B 1 30 ALA 30 63 63 ALA ALA B . n B 1 31 SER 31 64 64 SER SER B . n B 1 32 SER 32 65 65 SER SER B . n B 1 33 LYS 33 66 66 LYS LYS B . n B 1 34 GLY 34 67 67 GLY GLY B . n B 1 35 ALA 35 68 68 ALA ALA B . n B 1 36 ASN 36 69 69 ASN ASN B . n B 1 37 ALA 37 70 70 ALA ALA B . n B 1 38 SER 38 71 71 SER SER B . n B 1 39 ASN 39 72 72 ASN ASN B . n B 1 40 PRO 40 73 73 PRO PRO B . n B 1 41 GLY 41 74 74 GLY GLY B . n B 1 42 PRO 42 75 75 PRO PRO B . n B 1 43 PHE 43 76 76 PHE PHE B . n B 1 44 GLY 44 77 77 GLY GLY B . n B 1 45 ASP 45 78 78 ASP ASP B . n B 1 46 VAL 46 79 79 VAL VAL B . n B 1 47 LEU 47 80 80 LEU LEU B . n B 1 48 CYS 48 81 81 CYS CYS B . n B 1 49 ASP 49 82 82 ASP ASP B . n B 1 50 SER 50 83 83 SER SER B . n B 1 51 PRO 51 84 84 PRO PRO B . n B 1 52 TYR 52 85 85 TYR TYR B . n B 1 53 GLN 53 86 86 GLN GLN B . n B 1 54 LEU 54 87 87 LEU LEU B . n B 1 55 ILE 55 88 88 ILE ILE B . n B 1 56 LEU 56 89 89 LEU LEU B . n B 1 57 SER 57 90 90 SER SER B . n B 1 58 ALA 58 91 91 ALA ALA B . n B 1 59 PHE 59 92 92 PHE PHE B . n B 1 60 ASP 60 93 93 ASP ASP B . n B 1 61 PHE 61 94 94 PHE PHE B . n B 1 62 ILE 62 95 95 ILE ILE B . n B 1 63 LYS 63 96 96 LYS LYS B . n B 1 64 ASN 64 97 97 ASN ASN B . n B 1 65 SER 65 98 98 SER SER B . n B 1 66 GLY 66 99 99 GLY GLY B . n B 1 67 GLN 67 100 100 GLN GLN B . n B 1 68 GLU 68 101 101 GLU GLU B . n B 1 69 ALA 69 102 102 ALA ALA B . n B 1 70 SER 70 103 103 SER SER B . n B 1 71 PHE 71 104 104 PHE PHE B . n B 1 72 MET 72 105 105 MET MET B . n B 1 73 ILE 73 106 106 ILE ILE B . n B 1 74 TRP 74 107 107 TRP TRP B . n B 1 75 THR 75 108 108 THR THR B . n B 1 76 GLY 76 109 109 GLY GLY B . n B 1 77 ASP 77 110 110 ASP ASP B . n B 1 78 SER 78 111 111 SER SER B . n B 1 79 PRO 79 112 112 PRO PRO B . n B 1 80 PRO 80 113 113 PRO PRO B . n B 1 81 HIS 81 114 114 HIS HIS B . n B 1 82 VAL 82 115 115 VAL VAL B . n B 1 83 PRO 83 116 116 PRO PRO B . n B 1 84 VAL 84 117 117 VAL VAL B . n B 1 85 PRO 85 118 118 PRO PRO B . n B 1 86 GLU 86 119 119 GLU GLU B . n B 1 87 LEU 87 120 120 LEU LEU B . n B 1 88 SER 88 121 121 SER SER B . n B 1 89 THR 89 122 122 THR THR B . n B 1 90 ASP 90 123 123 ASP ASP B . n B 1 91 THR 91 124 124 THR THR B . n B 1 92 VAL 92 125 125 VAL VAL B . n B 1 93 ILE 93 126 126 ILE ILE B . n B 1 94 ASN 94 127 127 ASN ASN B . n B 1 95 VAL 95 128 128 VAL VAL B . n B 1 96 ILE 96 129 129 ILE ILE B . n B 1 97 THR 97 130 130 THR THR B . n B 1 98 ASN 98 131 131 ASN ASN B . n B 1 99 MET 99 132 132 MET MET B . n B 1 100 THR 100 133 133 THR THR B . n B 1 101 THR 101 134 134 THR THR B . n B 1 102 THR 102 135 135 THR THR B . n B 1 103 ILE 103 136 136 ILE ILE B . n B 1 104 GLN 104 137 137 GLN GLN B . n B 1 105 SER 105 138 138 SER SER B . n B 1 106 LEU 106 139 139 LEU LEU B . n B 1 107 PHE 107 140 140 PHE PHE B . n B 1 108 PRO 108 141 141 PRO PRO B . n B 1 109 ASN 109 142 142 ASN ASN B . n B 1 110 LEU 110 143 143 LEU LEU B . n B 1 111 GLN 111 144 144 GLN GLN B . n B 1 112 VAL 112 145 145 VAL VAL B . n B 1 113 PHE 113 146 146 PHE PHE B . n B 1 114 PRO 114 147 147 PRO PRO B . n B 1 115 ALA 115 148 148 ALA ALA B . n B 1 116 LEU 116 149 149 LEU LEU B . n B 1 117 GLY 117 150 150 GLY GLY B . n B 1 118 ASN 118 151 151 ASN ASN B . n B 1 119 HIS 119 152 152 HIS HIS B . n B 1 120 ASP 120 153 153 ASP ASP B . n B 1 121 TYR 121 154 154 TYR TYR B . n B 1 122 TRP 122 155 155 TRP TRP B . n B 1 123 PRO 123 156 156 PRO PRO B . n B 1 124 GLN 124 157 157 GLN GLN B . n B 1 125 ASP 125 158 158 ASP ASP B . n B 1 126 GLN 126 159 159 GLN GLN B . n B 1 127 LEU 127 160 160 LEU LEU B . n B 1 128 PRO 128 161 161 PRO PRO B . n B 1 129 VAL 129 162 162 VAL VAL B . n B 1 130 VAL 130 163 163 VAL VAL B . n B 1 131 THR 131 164 164 THR THR B . n B 1 132 SER 132 165 165 SER SER B . n B 1 133 LYS 133 166 166 LYS LYS B . n B 1 134 VAL 134 167 167 VAL VAL B . n B 1 135 TYR 135 168 168 TYR TYR B . n B 1 136 ASN 136 169 169 ASN ASN B . n B 1 137 ALA 137 170 170 ALA ALA B . n B 1 138 VAL 138 171 171 VAL VAL B . n B 1 139 ALA 139 172 172 ALA ALA B . n B 1 140 ASN 140 173 173 ASN ASN B . n B 1 141 LEU 141 174 174 LEU LEU B . n B 1 142 TRP 142 175 175 TRP TRP B . n B 1 143 LYS 143 176 176 LYS LYS B . n B 1 144 PRO 144 177 177 PRO PRO B . n B 1 145 TRP 145 178 178 TRP TRP B . n B 1 146 LEU 146 179 179 LEU LEU B . n B 1 147 ASP 147 180 180 ASP ASP B . n B 1 148 GLU 148 181 181 GLU GLU B . n B 1 149 GLU 149 182 182 GLU GLU B . n B 1 150 ALA 150 183 183 ALA ALA B . n B 1 151 ILE 151 184 184 ILE ILE B . n B 1 152 SER 152 185 185 SER SER B . n B 1 153 THR 153 186 186 THR THR B . n B 1 154 LEU 154 187 187 LEU LEU B . n B 1 155 ARG 155 188 188 ARG ARG B . n B 1 156 LYS 156 189 189 LYS LYS B . n B 1 157 GLY 157 190 190 GLY GLY B . n B 1 158 GLY 158 191 191 GLY GLY B . n B 1 159 PHE 159 192 192 PHE PHE B . n B 1 160 TYR 160 193 193 TYR TYR B . n B 1 161 SER 161 194 194 SER SER B . n B 1 162 GLN 162 195 195 GLN GLN B . n B 1 163 LYS 163 196 196 LYS LYS B . n B 1 164 VAL 164 197 197 VAL VAL B . n B 1 165 THR 165 198 198 THR THR B . n B 1 166 THR 166 199 199 THR THR B . n B 1 167 ASN 167 200 200 ASN ASN B . n B 1 168 PRO 168 201 201 PRO PRO B . n B 1 169 ASN 169 202 202 ASN ASN B . n B 1 170 LEU 170 203 203 LEU LEU B . n B 1 171 ARG 171 204 204 ARG ARG B . n B 1 172 ILE 172 205 205 ILE ILE B . n B 1 173 ILE 173 206 206 ILE ILE B . n B 1 174 SER 174 207 207 SER SER B . n B 1 175 LEU 175 208 208 LEU LEU B . n B 1 176 ASN 176 209 209 ASN ASN B . n B 1 177 THR 177 210 210 THR THR B . n B 1 178 ASN 178 211 211 ASN ASN B . n B 1 179 LEU 179 212 212 LEU LEU B . n B 1 180 TYR 180 213 213 TYR TYR B . n B 1 181 TYR 181 214 214 TYR TYR B . n B 1 182 GLY 182 215 215 GLY GLY B . n B 1 183 PRO 183 216 216 PRO PRO B . n B 1 184 ASN 184 217 217 ASN ASN B . n B 1 185 ILE 185 218 218 ILE ILE B . n B 1 186 MET 186 219 219 MET MET B . n B 1 187 THR 187 220 220 THR THR B . n B 1 188 LEU 188 221 221 LEU LEU B . n B 1 189 ASN 189 222 222 ASN ASN B . n B 1 190 LYS 190 223 223 LYS LYS B . n B 1 191 THR 191 224 224 THR THR B . n B 1 192 ASP 192 225 225 ASP ASP B . n B 1 193 PRO 193 226 226 PRO PRO B . n B 1 194 ALA 194 227 227 ALA ALA B . n B 1 195 ASN 195 228 228 ASN ASN B . n B 1 196 GLN 196 229 229 GLN GLN B . n B 1 197 PHE 197 230 230 PHE PHE B . n B 1 198 GLU 198 231 231 GLU GLU B . n B 1 199 TRP 199 232 232 TRP TRP B . n B 1 200 LEU 200 233 233 LEU LEU B . n B 1 201 GLU 201 234 234 GLU GLU B . n B 1 202 SER 202 235 235 SER SER B . n B 1 203 THR 203 236 236 THR THR B . n B 1 204 LEU 204 237 237 LEU LEU B . n B 1 205 ASN 205 238 238 ASN ASN B . n B 1 206 ASN 206 239 239 ASN ASN B . n B 1 207 SER 207 240 240 SER SER B . n B 1 208 GLN 208 241 241 GLN GLN B . n B 1 209 GLN 209 242 242 GLN GLN B . n B 1 210 ASN 210 243 243 ASN ASN B . n B 1 211 LYS 211 244 244 LYS LYS B . n B 1 212 GLU 212 245 245 GLU GLU B . n B 1 213 LYS 213 246 246 LYS LYS B . n B 1 214 VAL 214 247 247 VAL VAL B . n B 1 215 TYR 215 248 248 TYR TYR B . n B 1 216 ILE 216 249 249 ILE ILE B . n B 1 217 ILE 217 250 250 ILE ILE B . n B 1 218 ALA 218 251 251 ALA ALA B . n B 1 219 HIS 219 252 252 HIS HIS B . n B 1 220 VAL 220 253 253 VAL VAL B . n B 1 221 PRO 221 254 254 PRO PRO B . n B 1 222 VAL 222 255 255 VAL VAL B . n B 1 223 GLY 223 256 256 GLY GLY B . n B 1 224 TYR 224 257 257 TYR TYR B . n B 1 225 LEU 225 258 258 LEU LEU B . n B 1 226 PRO 226 259 259 PRO PRO B . n B 1 227 SER 227 260 260 SER SER B . n B 1 228 SER 228 261 261 SER SER B . n B 1 229 GLN 229 262 262 GLN GLN B . n B 1 230 ASN 230 263 263 ASN ASN B . n B 1 231 ILE 231 264 264 ILE ILE B . n B 1 232 THR 232 265 265 THR THR B . n B 1 233 ALA 233 266 266 ALA ALA B . n B 1 234 MET 234 267 267 MET MET B . n B 1 235 ARG 235 268 268 ARG ARG B . n B 1 236 GLU 236 269 269 GLU GLU B . n B 1 237 TYR 237 270 270 TYR TYR B . n B 1 238 TYR 238 271 271 TYR TYR B . n B 1 239 ASN 239 272 272 ASN ASN B . n B 1 240 GLU 240 273 273 GLU GLU B . n B 1 241 LYS 241 274 274 LYS LYS B . n B 1 242 LEU 242 275 275 LEU LEU B . n B 1 243 ILE 243 276 276 ILE ILE B . n B 1 244 ASP 244 277 277 ASP ASP B . n B 1 245 ILE 245 278 278 ILE ILE B . n B 1 246 PHE 246 279 279 PHE PHE B . n B 1 247 GLN 247 280 280 GLN GLN B . n B 1 248 LYS 248 281 281 LYS LYS B . n B 1 249 TYR 249 282 282 TYR TYR B . n B 1 250 SER 250 283 283 SER SER B . n B 1 251 ASP 251 284 284 ASP ASP B . n B 1 252 VAL 252 285 285 VAL VAL B . n B 1 253 ILE 253 286 286 ILE ILE B . n B 1 254 ALA 254 287 287 ALA ALA B . n B 1 255 GLY 255 288 288 GLY GLY B . n B 1 256 GLN 256 289 289 GLN GLN B . n B 1 257 PHE 257 290 290 PHE PHE B . n B 1 258 TYR 258 291 291 TYR TYR B . n B 1 259 GLY 259 292 292 GLY GLY B . n B 1 260 HIS 260 293 293 HIS HIS B . n B 1 261 THR 261 294 294 THR THR B . n B 1 262 HIS 262 295 295 HIS HIS B . n B 1 263 ARG 263 296 296 ARG ARG B . n B 1 264 ASP 264 297 297 ASP ASP B . n B 1 265 SER 265 298 298 SER SER B . n B 1 266 ILE 266 299 299 ILE ILE B . n B 1 267 MET 267 300 300 MET MET B . n B 1 268 VAL 268 301 301 VAL VAL B . n B 1 269 LEU 269 302 302 LEU LEU B . n B 1 270 SER 270 303 303 SER SER B . n B 1 271 ASP 271 304 304 ASP ASP B . n B 1 272 LYS 272 305 305 LYS LYS B . n B 1 273 LYS 273 306 306 LYS LYS B . n B 1 274 GLY 274 307 307 GLY GLY B . n B 1 275 SER 275 308 308 SER SER B . n B 1 276 PRO 276 309 309 PRO PRO B . n B 1 277 VAL 277 310 310 VAL VAL B . n B 1 278 ASN 278 311 311 ASN ASN B . n B 1 279 SER 279 312 312 SER SER B . n B 1 280 LEU 280 313 313 LEU LEU B . n B 1 281 PHE 281 314 314 PHE PHE B . n B 1 282 VAL 282 315 315 VAL VAL B . n B 1 283 ALA 283 316 316 ALA ALA B . n B 1 284 PRO 284 317 317 PRO PRO B . n B 1 285 ALA 285 318 318 ALA ALA B . n B 1 286 VAL 286 319 319 VAL VAL B . n B 1 287 THR 287 320 320 THR THR B . n B 1 288 PRO 288 321 321 PRO PRO B . n B 1 289 VAL 289 322 322 VAL VAL B . n B 1 290 LYS 290 323 323 LYS LYS B . n B 1 291 SER 291 324 324 SER SER B . n B 1 292 VAL 292 325 325 VAL VAL B . n B 1 293 LEU 293 326 326 LEU LEU B . n B 1 294 GLU 294 327 327 GLU GLU B . n B 1 295 LYS 295 328 328 LYS LYS B . n B 1 296 GLN 296 329 329 GLN GLN B . n B 1 297 THR 297 330 330 THR THR B . n B 1 298 ASN 298 331 331 ASN ASN B . n B 1 299 ASN 299 332 332 ASN ASN B . n B 1 300 PRO 300 333 333 PRO PRO B . n B 1 301 GLY 301 334 334 GLY GLY B . n B 1 302 ILE 302 335 335 ILE ILE B . n B 1 303 ARG 303 336 336 ARG ARG B . n B 1 304 LEU 304 337 337 LEU LEU B . n B 1 305 PHE 305 338 338 PHE PHE B . n B 1 306 GLN 306 339 339 GLN GLN B . n B 1 307 TYR 307 340 340 TYR TYR B . n B 1 308 ASP 308 341 341 ASP ASP B . n B 1 309 PRO 309 342 342 PRO PRO B . n B 1 310 ARG 310 343 343 ARG ARG B . n B 1 311 ASP 311 344 344 ASP ASP B . n B 1 312 TYR 312 345 345 TYR TYR B . n B 1 313 LYS 313 346 346 LYS LYS B . n B 1 314 LEU 314 347 347 LEU LEU B . n B 1 315 LEU 315 348 348 LEU LEU B . n B 1 316 ASP 316 349 349 ASP ASP B . n B 1 317 MET 317 350 350 MET MET B . n B 1 318 LEU 318 351 351 LEU LEU B . n B 1 319 GLN 319 352 352 GLN GLN B . n B 1 320 TYR 320 353 353 TYR TYR B . n B 1 321 TYR 321 354 354 TYR TYR B . n B 1 322 LEU 322 355 355 LEU LEU B . n B 1 323 ASN 323 356 356 ASN ASN B . n B 1 324 LEU 324 357 357 LEU LEU B . n B 1 325 THR 325 358 358 THR THR B . n B 1 326 GLU 326 359 359 GLU GLU B . n B 1 327 ALA 327 360 360 ALA ALA B . n B 1 328 ASN 328 361 361 ASN ASN B . n B 1 329 LEU 329 362 362 LEU LEU B . n B 1 330 LYS 330 363 363 LYS LYS B . n B 1 331 GLY 331 364 364 GLY GLY B . n B 1 332 GLU 332 365 365 GLU GLU B . n B 1 333 SER 333 366 366 SER SER B . n B 1 334 ILE 334 367 367 ILE ILE B . n B 1 335 TRP 335 368 368 TRP TRP B . n B 1 336 LYS 336 369 369 LYS LYS B . n B 1 337 LEU 337 370 370 LEU LEU B . n B 1 338 GLU 338 371 371 GLU GLU B . n B 1 339 TYR 339 372 372 TYR TYR B . n B 1 340 ILE 340 373 373 ILE ILE B . n B 1 341 LEU 341 374 374 LEU LEU B . n B 1 342 THR 342 375 375 THR THR B . n B 1 343 GLN 343 376 376 GLN GLN B . n B 1 344 THR 344 377 377 THR THR B . n B 1 345 TYR 345 378 378 TYR TYR B . n B 1 346 ASP 346 379 379 ASP ASP B . n B 1 347 ILE 347 380 380 ILE ILE B . n B 1 348 GLU 348 381 381 GLU GLU B . n B 1 349 ASP 349 382 382 ASP ASP B . n B 1 350 LEU 350 383 383 LEU LEU B . n B 1 351 GLN 351 384 384 GLN GLN B . n B 1 352 PRO 352 385 385 PRO PRO B . n B 1 353 GLU 353 386 386 GLU GLU B . n B 1 354 SER 354 387 387 SER SER B . n B 1 355 LEU 355 388 388 LEU LEU B . n B 1 356 TYR 356 389 389 TYR TYR B . n B 1 357 GLY 357 390 390 GLY GLY B . n B 1 358 LEU 358 391 391 LEU LEU B . n B 1 359 ALA 359 392 392 ALA ALA B . n B 1 360 LYS 360 393 393 LYS LYS B . n B 1 361 GLN 361 394 394 GLN GLN B . n B 1 362 PHE 362 395 395 PHE PHE B . n B 1 363 THR 363 396 396 THR THR B . n B 1 364 ILE 364 397 397 ILE ILE B . n B 1 365 LEU 365 398 398 LEU LEU B . n B 1 366 ASP 366 399 399 ASP ASP B . n B 1 367 SER 367 400 400 SER SER B . n B 1 368 LYS 368 401 401 LYS LYS B . n B 1 369 GLN 369 402 402 GLN GLN B . n B 1 370 PHE 370 403 403 PHE PHE B . n B 1 371 ILE 371 404 404 ILE ILE B . n B 1 372 LYS 372 405 405 LYS LYS B . n B 1 373 TYR 373 406 406 TYR TYR B . n B 1 374 TYR 374 407 407 TYR TYR B . n B 1 375 ASN 375 408 408 ASN ASN B . n B 1 376 TYR 376 409 409 TYR TYR B . n B 1 377 PHE 377 410 410 PHE PHE B . n B 1 378 PHE 378 411 411 PHE PHE B . n B 1 379 VAL 379 412 412 VAL VAL B . n B 1 380 SER 380 413 413 SER SER B . n B 1 381 TYR 381 414 414 TYR TYR B . n B 1 382 ASP 382 415 415 ASP ASP B . n B 1 383 SER 383 416 416 SER SER B . n B 1 384 SER 384 417 417 SER SER B . n B 1 385 VAL 385 418 418 VAL VAL B . n B 1 386 THR 386 419 419 THR THR B . n B 1 387 CYS 387 420 420 CYS CYS B . n B 1 388 ASP 388 421 421 ASP ASP B . n B 1 389 LYS 389 422 422 LYS LYS B . n B 1 390 THR 390 423 423 THR THR B . n B 1 391 CYS 391 424 424 CYS CYS B . n B 1 392 LYS 392 425 425 LYS LYS B . n B 1 393 ALA 393 426 426 ALA ALA B . n B 1 394 PHE 394 427 427 PHE PHE B . n B 1 395 GLN 395 428 428 GLN GLN B . n B 1 396 ILE 396 429 429 ILE ILE B . n B 1 397 CYS 397 430 430 CYS CYS B . n B 1 398 ALA 398 431 431 ALA ALA B . n B 1 399 ILE 399 432 432 ILE ILE B . n B 1 400 MET 400 433 433 MET MET B . n B 1 401 ASN 401 434 434 ASN ASN B . n B 1 402 LEU 402 435 435 LEU LEU B . n B 1 403 ASP 403 436 436 ASP ASP B . n B 1 404 ASN 404 437 437 ASN ASN B . n B 1 405 ILE 405 438 438 ILE ILE B . n B 1 406 SER 406 439 439 SER SER B . n B 1 407 TYR 407 440 440 TYR TYR B . n B 1 408 ALA 408 441 441 ALA ALA B . n B 1 409 ASP 409 442 442 ASP ASP B . n B 1 410 CYS 410 443 443 CYS CYS B . n C 1 1 PRO 1 34 34 PRO PRO C . n C 1 2 PRO 2 35 35 PRO PRO C . n C 1 3 ALA 3 36 36 ALA ALA C . n C 1 4 ILE 4 37 37 ILE ILE C . n C 1 5 GLY 5 38 38 GLY GLY C . n C 1 6 GLN 6 39 39 GLN GLN C . n C 1 7 PHE 7 40 40 PHE PHE C . n C 1 8 TRP 8 41 41 TRP TRP C . n C 1 9 HIS 9 42 42 HIS HIS C . n C 1 10 VAL 10 43 43 VAL VAL C . n C 1 11 THR 11 44 44 THR THR C . n C 1 12 ASP 12 45 45 ASP ASP C . n C 1 13 LEU 13 46 46 LEU LEU C . n C 1 14 HIS 14 47 47 HIS HIS C . n C 1 15 LEU 15 48 48 LEU LEU C . n C 1 16 ASP 16 49 49 ASP ASP C . n C 1 17 PRO 17 50 50 PRO PRO C . n C 1 18 THR 18 51 51 THR THR C . n C 1 19 TYR 19 52 52 TYR TYR C . n C 1 20 HIS 20 53 53 HIS HIS C . n C 1 21 ILE 21 54 54 ILE ILE C . n C 1 22 THR 22 55 55 THR THR C . n C 1 23 ASP 23 56 56 ASP ASP C . n C 1 24 ASP 24 57 57 ASP ASP C . n C 1 25 HIS 25 58 58 HIS HIS C . n C 1 26 THR 26 59 59 THR THR C . n C 1 27 LYS 27 60 60 LYS LYS C . n C 1 28 VAL 28 61 61 VAL VAL C . n C 1 29 CYS 29 62 62 CYS CYS C . n C 1 30 ALA 30 63 63 ALA ALA C . n C 1 31 SER 31 64 64 SER SER C . n C 1 32 SER 32 65 65 SER SER C . n C 1 33 LYS 33 66 66 LYS LYS C . n C 1 34 GLY 34 67 67 GLY GLY C . n C 1 35 ALA 35 68 68 ALA ALA C . n C 1 36 ASN 36 69 69 ASN ASN C . n C 1 37 ALA 37 70 70 ALA ALA C . n C 1 38 SER 38 71 71 SER SER C . n C 1 39 ASN 39 72 72 ASN ASN C . n C 1 40 PRO 40 73 73 PRO PRO C . n C 1 41 GLY 41 74 74 GLY GLY C . n C 1 42 PRO 42 75 75 PRO PRO C . n C 1 43 PHE 43 76 76 PHE PHE C . n C 1 44 GLY 44 77 77 GLY GLY C . n C 1 45 ASP 45 78 78 ASP ASP C . n C 1 46 VAL 46 79 79 VAL VAL C . n C 1 47 LEU 47 80 80 LEU LEU C . n C 1 48 CYS 48 81 81 CYS CYS C . n C 1 49 ASP 49 82 82 ASP ASP C . n C 1 50 SER 50 83 83 SER SER C . n C 1 51 PRO 51 84 84 PRO PRO C . n C 1 52 TYR 52 85 85 TYR TYR C . n C 1 53 GLN 53 86 86 GLN GLN C . n C 1 54 LEU 54 87 87 LEU LEU C . n C 1 55 ILE 55 88 88 ILE ILE C . n C 1 56 LEU 56 89 89 LEU LEU C . n C 1 57 SER 57 90 90 SER SER C . n C 1 58 ALA 58 91 91 ALA ALA C . n C 1 59 PHE 59 92 92 PHE PHE C . n C 1 60 ASP 60 93 93 ASP ASP C . n C 1 61 PHE 61 94 94 PHE PHE C . n C 1 62 ILE 62 95 95 ILE ILE C . n C 1 63 LYS 63 96 96 LYS LYS C . n C 1 64 ASN 64 97 97 ASN ASN C . n C 1 65 SER 65 98 98 SER SER C . n C 1 66 GLY 66 99 99 GLY GLY C . n C 1 67 GLN 67 100 100 GLN GLN C . n C 1 68 GLU 68 101 101 GLU GLU C . n C 1 69 ALA 69 102 102 ALA ALA C . n C 1 70 SER 70 103 103 SER SER C . n C 1 71 PHE 71 104 104 PHE PHE C . n C 1 72 MET 72 105 105 MET MET C . n C 1 73 ILE 73 106 106 ILE ILE C . n C 1 74 TRP 74 107 107 TRP TRP C . n C 1 75 THR 75 108 108 THR THR C . n C 1 76 GLY 76 109 109 GLY GLY C . n C 1 77 ASP 77 110 110 ASP ASP C . n C 1 78 SER 78 111 111 SER SER C . n C 1 79 PRO 79 112 112 PRO PRO C . n C 1 80 PRO 80 113 113 PRO PRO C . n C 1 81 HIS 81 114 114 HIS HIS C . n C 1 82 VAL 82 115 115 VAL VAL C . n C 1 83 PRO 83 116 116 PRO PRO C . n C 1 84 VAL 84 117 117 VAL VAL C . n C 1 85 PRO 85 118 118 PRO PRO C . n C 1 86 GLU 86 119 119 GLU GLU C . n C 1 87 LEU 87 120 120 LEU LEU C . n C 1 88 SER 88 121 121 SER SER C . n C 1 89 THR 89 122 122 THR THR C . n C 1 90 ASP 90 123 123 ASP ASP C . n C 1 91 THR 91 124 124 THR THR C . n C 1 92 VAL 92 125 125 VAL VAL C . n C 1 93 ILE 93 126 126 ILE ILE C . n C 1 94 ASN 94 127 127 ASN ASN C . n C 1 95 VAL 95 128 128 VAL VAL C . n C 1 96 ILE 96 129 129 ILE ILE C . n C 1 97 THR 97 130 130 THR THR C . n C 1 98 ASN 98 131 131 ASN ASN C . n C 1 99 MET 99 132 132 MET MET C . n C 1 100 THR 100 133 133 THR THR C . n C 1 101 THR 101 134 134 THR THR C . n C 1 102 THR 102 135 135 THR THR C . n C 1 103 ILE 103 136 136 ILE ILE C . n C 1 104 GLN 104 137 137 GLN GLN C . n C 1 105 SER 105 138 138 SER SER C . n C 1 106 LEU 106 139 139 LEU LEU C . n C 1 107 PHE 107 140 140 PHE PHE C . n C 1 108 PRO 108 141 141 PRO PRO C . n C 1 109 ASN 109 142 142 ASN ASN C . n C 1 110 LEU 110 143 143 LEU LEU C . n C 1 111 GLN 111 144 144 GLN GLN C . n C 1 112 VAL 112 145 145 VAL VAL C . n C 1 113 PHE 113 146 146 PHE PHE C . n C 1 114 PRO 114 147 147 PRO PRO C . n C 1 115 ALA 115 148 148 ALA ALA C . n C 1 116 LEU 116 149 149 LEU LEU C . n C 1 117 GLY 117 150 150 GLY GLY C . n C 1 118 ASN 118 151 151 ASN ASN C . n C 1 119 HIS 119 152 152 HIS HIS C . n C 1 120 ASP 120 153 153 ASP ASP C . n C 1 121 TYR 121 154 154 TYR TYR C . n C 1 122 TRP 122 155 155 TRP TRP C . n C 1 123 PRO 123 156 156 PRO PRO C . n C 1 124 GLN 124 157 157 GLN GLN C . n C 1 125 ASP 125 158 158 ASP ASP C . n C 1 126 GLN 126 159 159 GLN GLN C . n C 1 127 LEU 127 160 160 LEU LEU C . n C 1 128 PRO 128 161 161 PRO PRO C . n C 1 129 VAL 129 162 162 VAL VAL C . n C 1 130 VAL 130 163 163 VAL VAL C . n C 1 131 THR 131 164 164 THR THR C . n C 1 132 SER 132 165 165 SER SER C . n C 1 133 LYS 133 166 166 LYS LYS C . n C 1 134 VAL 134 167 167 VAL VAL C . n C 1 135 TYR 135 168 168 TYR TYR C . n C 1 136 ASN 136 169 169 ASN ASN C . n C 1 137 ALA 137 170 170 ALA ALA C . n C 1 138 VAL 138 171 171 VAL VAL C . n C 1 139 ALA 139 172 172 ALA ALA C . n C 1 140 ASN 140 173 173 ASN ASN C . n C 1 141 LEU 141 174 174 LEU LEU C . n C 1 142 TRP 142 175 175 TRP TRP C . n C 1 143 LYS 143 176 176 LYS LYS C . n C 1 144 PRO 144 177 177 PRO PRO C . n C 1 145 TRP 145 178 178 TRP TRP C . n C 1 146 LEU 146 179 179 LEU LEU C . n C 1 147 ASP 147 180 180 ASP ASP C . n C 1 148 GLU 148 181 181 GLU GLU C . n C 1 149 GLU 149 182 182 GLU GLU C . n C 1 150 ALA 150 183 183 ALA ALA C . n C 1 151 ILE 151 184 184 ILE ILE C . n C 1 152 SER 152 185 185 SER SER C . n C 1 153 THR 153 186 186 THR THR C . n C 1 154 LEU 154 187 187 LEU LEU C . n C 1 155 ARG 155 188 188 ARG ARG C . n C 1 156 LYS 156 189 189 LYS LYS C . n C 1 157 GLY 157 190 190 GLY GLY C . n C 1 158 GLY 158 191 191 GLY GLY C . n C 1 159 PHE 159 192 192 PHE PHE C . n C 1 160 TYR 160 193 193 TYR TYR C . n C 1 161 SER 161 194 194 SER SER C . n C 1 162 GLN 162 195 195 GLN GLN C . n C 1 163 LYS 163 196 196 LYS LYS C . n C 1 164 VAL 164 197 197 VAL VAL C . n C 1 165 THR 165 198 198 THR THR C . n C 1 166 THR 166 199 199 THR THR C . n C 1 167 ASN 167 200 200 ASN ASN C . n C 1 168 PRO 168 201 201 PRO PRO C . n C 1 169 ASN 169 202 202 ASN ASN C . n C 1 170 LEU 170 203 203 LEU LEU C . n C 1 171 ARG 171 204 204 ARG ARG C . n C 1 172 ILE 172 205 205 ILE ILE C . n C 1 173 ILE 173 206 206 ILE ILE C . n C 1 174 SER 174 207 207 SER SER C . n C 1 175 LEU 175 208 208 LEU LEU C . n C 1 176 ASN 176 209 209 ASN ASN C . n C 1 177 THR 177 210 210 THR THR C . n C 1 178 ASN 178 211 211 ASN ASN C . n C 1 179 LEU 179 212 212 LEU LEU C . n C 1 180 TYR 180 213 213 TYR TYR C . n C 1 181 TYR 181 214 214 TYR TYR C . n C 1 182 GLY 182 215 215 GLY GLY C . n C 1 183 PRO 183 216 216 PRO PRO C . n C 1 184 ASN 184 217 217 ASN ASN C . n C 1 185 ILE 185 218 218 ILE ILE C . n C 1 186 MET 186 219 219 MET MET C . n C 1 187 THR 187 220 220 THR THR C . n C 1 188 LEU 188 221 221 LEU LEU C . n C 1 189 ASN 189 222 222 ASN ASN C . n C 1 190 LYS 190 223 223 LYS LYS C . n C 1 191 THR 191 224 224 THR THR C . n C 1 192 ASP 192 225 225 ASP ASP C . n C 1 193 PRO 193 226 226 PRO PRO C . n C 1 194 ALA 194 227 227 ALA ALA C . n C 1 195 ASN 195 228 228 ASN ASN C . n C 1 196 GLN 196 229 229 GLN GLN C . n C 1 197 PHE 197 230 230 PHE PHE C . n C 1 198 GLU 198 231 231 GLU GLU C . n C 1 199 TRP 199 232 232 TRP TRP C . n C 1 200 LEU 200 233 233 LEU LEU C . n C 1 201 GLU 201 234 234 GLU GLU C . n C 1 202 SER 202 235 235 SER SER C . n C 1 203 THR 203 236 236 THR THR C . n C 1 204 LEU 204 237 237 LEU LEU C . n C 1 205 ASN 205 238 238 ASN ASN C . n C 1 206 ASN 206 239 239 ASN ASN C . n C 1 207 SER 207 240 240 SER SER C . n C 1 208 GLN 208 241 241 GLN GLN C . n C 1 209 GLN 209 242 242 GLN GLN C . n C 1 210 ASN 210 243 243 ASN ASN C . n C 1 211 LYS 211 244 244 LYS LYS C . n C 1 212 GLU 212 245 245 GLU GLU C . n C 1 213 LYS 213 246 246 LYS LYS C . n C 1 214 VAL 214 247 247 VAL VAL C . n C 1 215 TYR 215 248 248 TYR TYR C . n C 1 216 ILE 216 249 249 ILE ILE C . n C 1 217 ILE 217 250 250 ILE ILE C . n C 1 218 ALA 218 251 251 ALA ALA C . n C 1 219 HIS 219 252 252 HIS HIS C . n C 1 220 VAL 220 253 253 VAL VAL C . n C 1 221 PRO 221 254 254 PRO PRO C . n C 1 222 VAL 222 255 255 VAL VAL C . n C 1 223 GLY 223 256 256 GLY GLY C . n C 1 224 TYR 224 257 257 TYR TYR C . n C 1 225 LEU 225 258 258 LEU LEU C . n C 1 226 PRO 226 259 259 PRO PRO C . n C 1 227 SER 227 260 260 SER SER C . n C 1 228 SER 228 261 261 SER SER C . n C 1 229 GLN 229 262 262 GLN GLN C . n C 1 230 ASN 230 263 263 ASN ASN C . n C 1 231 ILE 231 264 264 ILE ILE C . n C 1 232 THR 232 265 265 THR THR C . n C 1 233 ALA 233 266 266 ALA ALA C . n C 1 234 MET 234 267 267 MET MET C . n C 1 235 ARG 235 268 268 ARG ARG C . n C 1 236 GLU 236 269 269 GLU GLU C . n C 1 237 TYR 237 270 270 TYR TYR C . n C 1 238 TYR 238 271 271 TYR TYR C . n C 1 239 ASN 239 272 272 ASN ASN C . n C 1 240 GLU 240 273 273 GLU GLU C . n C 1 241 LYS 241 274 274 LYS LYS C . n C 1 242 LEU 242 275 275 LEU LEU C . n C 1 243 ILE 243 276 276 ILE ILE C . n C 1 244 ASP 244 277 277 ASP ASP C . n C 1 245 ILE 245 278 278 ILE ILE C . n C 1 246 PHE 246 279 279 PHE PHE C . n C 1 247 GLN 247 280 280 GLN GLN C . n C 1 248 LYS 248 281 281 LYS LYS C . n C 1 249 TYR 249 282 282 TYR TYR C . n C 1 250 SER 250 283 283 SER SER C . n C 1 251 ASP 251 284 284 ASP ASP C . n C 1 252 VAL 252 285 285 VAL VAL C . n C 1 253 ILE 253 286 286 ILE ILE C . n C 1 254 ALA 254 287 287 ALA ALA C . n C 1 255 GLY 255 288 288 GLY GLY C . n C 1 256 GLN 256 289 289 GLN GLN C . n C 1 257 PHE 257 290 290 PHE PHE C . n C 1 258 TYR 258 291 291 TYR TYR C . n C 1 259 GLY 259 292 292 GLY GLY C . n C 1 260 HIS 260 293 293 HIS HIS C . n C 1 261 THR 261 294 294 THR THR C . n C 1 262 HIS 262 295 295 HIS HIS C . n C 1 263 ARG 263 296 296 ARG ARG C . n C 1 264 ASP 264 297 297 ASP ASP C . n C 1 265 SER 265 298 298 SER SER C . n C 1 266 ILE 266 299 299 ILE ILE C . n C 1 267 MET 267 300 300 MET MET C . n C 1 268 VAL 268 301 301 VAL VAL C . n C 1 269 LEU 269 302 302 LEU LEU C . n C 1 270 SER 270 303 303 SER SER C . n C 1 271 ASP 271 304 304 ASP ASP C . n C 1 272 LYS 272 305 305 LYS LYS C . n C 1 273 LYS 273 306 306 LYS LYS C . n C 1 274 GLY 274 307 307 GLY GLY C . n C 1 275 SER 275 308 308 SER SER C . n C 1 276 PRO 276 309 309 PRO PRO C . n C 1 277 VAL 277 310 310 VAL VAL C . n C 1 278 ASN 278 311 311 ASN ASN C . n C 1 279 SER 279 312 312 SER SER C . n C 1 280 LEU 280 313 313 LEU LEU C . n C 1 281 PHE 281 314 314 PHE PHE C . n C 1 282 VAL 282 315 315 VAL VAL C . n C 1 283 ALA 283 316 316 ALA ALA C . n C 1 284 PRO 284 317 317 PRO PRO C . n C 1 285 ALA 285 318 318 ALA ALA C . n C 1 286 VAL 286 319 319 VAL VAL C . n C 1 287 THR 287 320 320 THR THR C . n C 1 288 PRO 288 321 321 PRO PRO C . n C 1 289 VAL 289 322 322 VAL VAL C . n C 1 290 LYS 290 323 323 LYS LYS C . n C 1 291 SER 291 324 324 SER SER C . n C 1 292 VAL 292 325 325 VAL VAL C . n C 1 293 LEU 293 326 326 LEU LEU C . n C 1 294 GLU 294 327 327 GLU GLU C . n C 1 295 LYS 295 328 328 LYS LYS C . n C 1 296 GLN 296 329 329 GLN GLN C . n C 1 297 THR 297 330 330 THR THR C . n C 1 298 ASN 298 331 331 ASN ASN C . n C 1 299 ASN 299 332 332 ASN ASN C . n C 1 300 PRO 300 333 333 PRO PRO C . n C 1 301 GLY 301 334 334 GLY GLY C . n C 1 302 ILE 302 335 335 ILE ILE C . n C 1 303 ARG 303 336 336 ARG ARG C . n C 1 304 LEU 304 337 337 LEU LEU C . n C 1 305 PHE 305 338 338 PHE PHE C . n C 1 306 GLN 306 339 339 GLN GLN C . n C 1 307 TYR 307 340 340 TYR TYR C . n C 1 308 ASP 308 341 341 ASP ASP C . n C 1 309 PRO 309 342 342 PRO PRO C . n C 1 310 ARG 310 343 343 ARG ARG C . n C 1 311 ASP 311 344 344 ASP ASP C . n C 1 312 TYR 312 345 345 TYR TYR C . n C 1 313 LYS 313 346 346 LYS LYS C . n C 1 314 LEU 314 347 347 LEU LEU C . n C 1 315 LEU 315 348 348 LEU LEU C . n C 1 316 ASP 316 349 349 ASP ASP C . n C 1 317 MET 317 350 350 MET MET C . n C 1 318 LEU 318 351 351 LEU LEU C . n C 1 319 GLN 319 352 352 GLN GLN C . n C 1 320 TYR 320 353 353 TYR TYR C . n C 1 321 TYR 321 354 354 TYR TYR C . n C 1 322 LEU 322 355 355 LEU LEU C . n C 1 323 ASN 323 356 356 ASN ASN C . n C 1 324 LEU 324 357 357 LEU LEU C . n C 1 325 THR 325 358 358 THR THR C . n C 1 326 GLU 326 359 359 GLU GLU C . n C 1 327 ALA 327 360 360 ALA ALA C . n C 1 328 ASN 328 361 361 ASN ASN C . n C 1 329 LEU 329 362 362 LEU LEU C . n C 1 330 LYS 330 363 363 LYS LYS C . n C 1 331 GLY 331 364 364 GLY GLY C . n C 1 332 GLU 332 365 365 GLU GLU C . n C 1 333 SER 333 366 366 SER SER C . n C 1 334 ILE 334 367 367 ILE ILE C . n C 1 335 TRP 335 368 368 TRP TRP C . n C 1 336 LYS 336 369 369 LYS LYS C . n C 1 337 LEU 337 370 370 LEU LEU C . n C 1 338 GLU 338 371 371 GLU GLU C . n C 1 339 TYR 339 372 372 TYR TYR C . n C 1 340 ILE 340 373 373 ILE ILE C . n C 1 341 LEU 341 374 374 LEU LEU C . n C 1 342 THR 342 375 375 THR THR C . n C 1 343 GLN 343 376 376 GLN GLN C . n C 1 344 THR 344 377 377 THR THR C . n C 1 345 TYR 345 378 378 TYR TYR C . n C 1 346 ASP 346 379 379 ASP ASP C . n C 1 347 ILE 347 380 380 ILE ILE C . n C 1 348 GLU 348 381 381 GLU GLU C . n C 1 349 ASP 349 382 382 ASP ASP C . n C 1 350 LEU 350 383 383 LEU LEU C . n C 1 351 GLN 351 384 384 GLN GLN C . n C 1 352 PRO 352 385 385 PRO PRO C . n C 1 353 GLU 353 386 386 GLU GLU C . n C 1 354 SER 354 387 387 SER SER C . n C 1 355 LEU 355 388 388 LEU LEU C . n C 1 356 TYR 356 389 389 TYR TYR C . n C 1 357 GLY 357 390 390 GLY GLY C . n C 1 358 LEU 358 391 391 LEU LEU C . n C 1 359 ALA 359 392 392 ALA ALA C . n C 1 360 LYS 360 393 393 LYS LYS C . n C 1 361 GLN 361 394 394 GLN GLN C . n C 1 362 PHE 362 395 395 PHE PHE C . n C 1 363 THR 363 396 396 THR THR C . n C 1 364 ILE 364 397 397 ILE ILE C . n C 1 365 LEU 365 398 398 LEU LEU C . n C 1 366 ASP 366 399 399 ASP ASP C . n C 1 367 SER 367 400 400 SER SER C . n C 1 368 LYS 368 401 401 LYS LYS C . n C 1 369 GLN 369 402 402 GLN GLN C . n C 1 370 PHE 370 403 403 PHE PHE C . n C 1 371 ILE 371 404 404 ILE ILE C . n C 1 372 LYS 372 405 405 LYS LYS C . n C 1 373 TYR 373 406 406 TYR TYR C . n C 1 374 TYR 374 407 407 TYR TYR C . n C 1 375 ASN 375 408 408 ASN ASN C . n C 1 376 TYR 376 409 409 TYR TYR C . n C 1 377 PHE 377 410 410 PHE PHE C . n C 1 378 PHE 378 411 411 PHE PHE C . n C 1 379 VAL 379 412 412 VAL VAL C . n C 1 380 SER 380 413 413 SER SER C . n C 1 381 TYR 381 414 414 TYR TYR C . n C 1 382 ASP 382 415 415 ASP ASP C . n C 1 383 SER 383 416 416 SER SER C . n C 1 384 SER 384 417 417 SER SER C . n C 1 385 VAL 385 418 418 VAL VAL C . n C 1 386 THR 386 419 419 THR THR C . n C 1 387 CYS 387 420 420 CYS CYS C . n C 1 388 ASP 388 421 421 ASP ASP C . n C 1 389 LYS 389 422 422 LYS LYS C . n C 1 390 THR 390 423 423 THR THR C . n C 1 391 CYS 391 424 424 CYS CYS C . n C 1 392 LYS 392 425 425 LYS LYS C . n C 1 393 ALA 393 426 426 ALA ALA C . n C 1 394 PHE 394 427 427 PHE PHE C . n C 1 395 GLN 395 428 428 GLN GLN C . n C 1 396 ILE 396 429 429 ILE ILE C . n C 1 397 CYS 397 430 430 CYS CYS C . n C 1 398 ALA 398 431 431 ALA ALA C . n C 1 399 ILE 399 432 432 ILE ILE C . n C 1 400 MET 400 433 433 MET MET C . n C 1 401 ASN 401 434 434 ASN ASN C . n C 1 402 LEU 402 435 435 LEU LEU C . n C 1 403 ASP 403 436 436 ASP ASP C . n C 1 404 ASN 404 437 437 ASN ASN C . n C 1 405 ILE 405 438 438 ILE ILE C . n C 1 406 SER 406 439 439 SER SER C . n C 1 407 TYR 407 440 440 TYR TYR C . n C 1 408 ALA 408 441 441 ALA ALA C . n C 1 409 ASP 409 442 442 ASP ASP C . n C 1 410 CYS 410 443 443 CYS CYS C . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code D 2 ZN 1 701 701 ZN ZN A . E 2 ZN 1 702 702 ZN ZN A . F 3 NAG 1 703 801 NAG NAG A . G 3 NAG 1 704 802 NAG NAG A . H 3 NAG 1 705 803 NAG NAG A . I 4 MLI 1 706 3 MLI MLI A . J 2 ZN 1 701 701 ZN ZN B . K 2 ZN 1 702 702 ZN ZN B . L 3 NAG 1 703 801 NAG NAG B . M 3 NAG 1 704 802 NAG NAG B . N 3 NAG 1 705 803 NAG NAG B . O 4 MLI 1 706 4 MLI MLI B . P 5 GOL 1 707 1 GOL GOL B . Q 2 ZN 1 701 701 ZN ZN C . R 2 ZN 1 702 702 ZN ZN C . S 3 NAG 1 703 801 NAG NAG C . T 3 NAG 1 704 802 NAG NAG C . U 3 NAG 1 705 803 NAG NAG C . V 4 MLI 1 706 5 MLI MLI C . W 5 GOL 1 707 2 GOL GOL C . X 6 HOH 1 801 300 HOH HOH A . X 6 HOH 2 802 7 HOH HOH A . X 6 HOH 3 803 191 HOH HOH A . X 6 HOH 4 804 105 HOH HOH A . X 6 HOH 5 805 121 HOH HOH A . X 6 HOH 6 806 188 HOH HOH A . X 6 HOH 7 807 194 HOH HOH A . X 6 HOH 8 808 14 HOH HOH A . X 6 HOH 9 809 199 HOH HOH A . X 6 HOH 10 810 2 HOH HOH A . X 6 HOH 11 811 235 HOH HOH A . X 6 HOH 12 812 3 HOH HOH A . X 6 HOH 13 813 15 HOH HOH A . X 6 HOH 14 814 17 HOH HOH A . X 6 HOH 15 815 12 HOH HOH A . X 6 HOH 16 816 9 HOH HOH A . X 6 HOH 17 817 103 HOH HOH A . X 6 HOH 18 818 1 HOH HOH A . X 6 HOH 19 819 104 HOH HOH A . X 6 HOH 20 820 189 HOH HOH A . X 6 HOH 21 821 197 HOH HOH A . X 6 HOH 22 822 8 HOH HOH A . X 6 HOH 23 823 11 HOH HOH A . X 6 HOH 24 824 4 HOH HOH A . X 6 HOH 25 825 302 HOH HOH A . X 6 HOH 26 826 6 HOH HOH A . X 6 HOH 27 827 10 HOH HOH A . X 6 HOH 28 828 292 HOH HOH A . X 6 HOH 29 829 60 HOH HOH A . X 6 HOH 30 830 108 HOH HOH A . X 6 HOH 31 831 63 HOH HOH A . X 6 HOH 32 832 301 HOH HOH A . X 6 HOH 33 833 18 HOH HOH A . X 6 HOH 34 834 123 HOH HOH A . X 6 HOH 35 835 109 HOH HOH A . X 6 HOH 36 836 122 HOH HOH A . X 6 HOH 37 837 236 HOH HOH A . X 6 HOH 38 838 13 HOH HOH A . X 6 HOH 39 839 16 HOH HOH A . X 6 HOH 40 840 198 HOH HOH A . X 6 HOH 41 841 5 HOH HOH A . X 6 HOH 42 842 120 HOH HOH A . X 6 HOH 43 843 190 HOH HOH A . X 6 HOH 44 844 19 HOH HOH A . X 6 HOH 45 845 192 HOH HOH A . X 6 HOH 46 846 61 HOH HOH A . X 6 HOH 47 847 62 HOH HOH A . X 6 HOH 48 848 299 HOH HOH A . X 6 HOH 49 849 195 HOH HOH A . X 6 HOH 50 850 193 HOH HOH A . X 6 HOH 51 851 21 HOH HOH A . X 6 HOH 52 852 22 HOH HOH A . X 6 HOH 53 853 59 HOH HOH A . X 6 HOH 54 854 233 HOH HOH A . X 6 HOH 55 855 196 HOH HOH A . X 6 HOH 56 856 119 HOH HOH A . Y 6 HOH 1 801 115 HOH HOH B . Y 6 HOH 2 802 34 HOH HOH B . Y 6 HOH 3 803 250 HOH HOH B . Y 6 HOH 4 804 38 HOH HOH B . Y 6 HOH 5 805 36 HOH HOH B . Y 6 HOH 6 806 80 HOH HOH B . Y 6 HOH 7 807 94 HOH HOH B . Y 6 HOH 8 808 89 HOH HOH B . Y 6 HOH 9 809 44 HOH HOH B . Y 6 HOH 10 810 42 HOH HOH B . Y 6 HOH 11 811 258 HOH HOH B . Y 6 HOH 12 812 24 HOH HOH B . Y 6 HOH 13 813 87 HOH HOH B . Y 6 HOH 14 814 27 HOH HOH B . Y 6 HOH 15 815 260 HOH HOH B . Y 6 HOH 16 816 47 HOH HOH B . Y 6 HOH 17 817 93 HOH HOH B . Y 6 HOH 18 818 252 HOH HOH B . Y 6 HOH 19 819 95 HOH HOH B . Y 6 HOH 20 820 39 HOH HOH B . Y 6 HOH 21 821 86 HOH HOH B . Y 6 HOH 22 822 84 HOH HOH B . Y 6 HOH 23 823 231 HOH HOH B . Y 6 HOH 24 824 101 HOH HOH B . Y 6 HOH 25 825 237 HOH HOH B . Y 6 HOH 26 826 77 HOH HOH B . Y 6 HOH 27 827 29 HOH HOH B . Y 6 HOH 28 828 232 HOH HOH B . Y 6 HOH 29 829 40 HOH HOH B . Y 6 HOH 30 830 37 HOH HOH B . Y 6 HOH 31 831 255 HOH HOH B . Y 6 HOH 32 832 249 HOH HOH B . Y 6 HOH 33 833 43 HOH HOH B . Y 6 HOH 34 834 32 HOH HOH B . Y 6 HOH 35 835 263 HOH HOH B . Y 6 HOH 36 836 45 HOH HOH B . Y 6 HOH 37 837 210 HOH HOH B . Y 6 HOH 38 838 204 HOH HOH B . Y 6 HOH 39 839 25 HOH HOH B . Y 6 HOH 40 840 98 HOH HOH B . Y 6 HOH 41 841 247 HOH HOH B . Y 6 HOH 42 842 219 HOH HOH B . Y 6 HOH 43 843 242 HOH HOH B . Y 6 HOH 44 844 41 HOH HOH B . Y 6 HOH 45 845 215 HOH HOH B . Y 6 HOH 46 846 83 HOH HOH B . Y 6 HOH 47 847 212 HOH HOH B . Y 6 HOH 48 848 223 HOH HOH B . Y 6 HOH 49 849 230 HOH HOH B . Y 6 HOH 50 850 200 HOH HOH B . Y 6 HOH 51 851 99 HOH HOH B . Y 6 HOH 52 852 31 HOH HOH B . Y 6 HOH 53 853 30 HOH HOH B . Y 6 HOH 54 854 117 HOH HOH B . Y 6 HOH 55 855 85 HOH HOH B . Y 6 HOH 56 856 48 HOH HOH B . Y 6 HOH 57 857 281 HOH HOH B . Y 6 HOH 58 858 244 HOH HOH B . Y 6 HOH 59 859 26 HOH HOH B . Y 6 HOH 60 860 312 HOH HOH B . Y 6 HOH 61 861 270 HOH HOH B . Y 6 HOH 62 862 28 HOH HOH B . Y 6 HOH 63 863 102 HOH HOH B . Y 6 HOH 64 864 245 HOH HOH B . Y 6 HOH 65 865 256 HOH HOH B . Y 6 HOH 66 866 308 HOH HOH B . Y 6 HOH 67 867 202 HOH HOH B . Y 6 HOH 68 868 78 HOH HOH B . Y 6 HOH 69 869 239 HOH HOH B . Y 6 HOH 70 870 116 HOH HOH B . Y 6 HOH 71 871 226 HOH HOH B . Y 6 HOH 72 872 100 HOH HOH B . Y 6 HOH 73 873 238 HOH HOH B . Y 6 HOH 74 874 23 HOH HOH B . Y 6 HOH 75 875 79 HOH HOH B . Y 6 HOH 76 876 97 HOH HOH B . Y 6 HOH 77 877 241 HOH HOH B . Y 6 HOH 78 878 313 HOH HOH B . Y 6 HOH 79 879 310 HOH HOH B . Y 6 HOH 80 880 127 HOH HOH B . Y 6 HOH 81 881 203 HOH HOH B . Y 6 HOH 82 882 253 HOH HOH B . Y 6 HOH 83 883 159 HOH HOH B . Y 6 HOH 84 884 211 HOH HOH B . Y 6 HOH 85 885 91 HOH HOH B . Y 6 HOH 86 886 251 HOH HOH B . Y 6 HOH 87 887 46 HOH HOH B . Y 6 HOH 88 888 214 HOH HOH B . Y 6 HOH 89 889 227 HOH HOH B . Y 6 HOH 90 890 228 HOH HOH B . Y 6 HOH 91 891 82 HOH HOH B . Y 6 HOH 92 892 266 HOH HOH B . Y 6 HOH 93 893 257 HOH HOH B . Y 6 HOH 94 894 35 HOH HOH B . Y 6 HOH 95 895 201 HOH HOH B . Y 6 HOH 96 896 145 HOH HOH B . Y 6 HOH 97 897 311 HOH HOH B . Y 6 HOH 98 898 218 HOH HOH B . Y 6 HOH 99 899 20 HOH HOH B . Y 6 HOH 100 900 81 HOH HOH B . Y 6 HOH 101 901 248 HOH HOH B . Y 6 HOH 102 902 213 HOH HOH B . Y 6 HOH 103 903 240 HOH HOH B . Y 6 HOH 104 904 220 HOH HOH B . Y 6 HOH 105 905 157 HOH HOH B . Y 6 HOH 106 906 293 HOH HOH B . Y 6 HOH 107 907 125 HOH HOH B . Y 6 HOH 108 908 224 HOH HOH B . Y 6 HOH 109 909 216 HOH HOH B . Y 6 HOH 110 910 309 HOH HOH B . Y 6 HOH 111 911 33 HOH HOH B . Y 6 HOH 112 912 222 HOH HOH B . Y 6 HOH 113 913 243 HOH HOH B . Y 6 HOH 114 914 307 HOH HOH B . Y 6 HOH 115 915 205 HOH HOH B . Y 6 HOH 116 916 217 HOH HOH B . Y 6 HOH 117 917 221 HOH HOH B . Y 6 HOH 118 918 259 HOH HOH B . Y 6 HOH 119 919 246 HOH HOH B . Y 6 HOH 120 920 254 HOH HOH B . Y 6 HOH 121 921 90 HOH HOH B . Y 6 HOH 122 922 229 HOH HOH B . Y 6 HOH 123 923 124 HOH HOH B . Y 6 HOH 124 924 207 HOH HOH B . Y 6 HOH 125 925 206 HOH HOH B . Y 6 HOH 126 926 209 HOH HOH B . Z 6 HOH 1 801 264 HOH HOH C . Z 6 HOH 2 802 262 HOH HOH C . Z 6 HOH 3 803 54 HOH HOH C . Z 6 HOH 4 804 174 HOH HOH C . Z 6 HOH 5 805 144 HOH HOH C . Z 6 HOH 6 806 168 HOH HOH C . Z 6 HOH 7 807 52 HOH HOH C . Z 6 HOH 8 808 285 HOH HOH C . Z 6 HOH 9 809 150 HOH HOH C . Z 6 HOH 10 810 294 HOH HOH C . Z 6 HOH 11 811 143 HOH HOH C . Z 6 HOH 12 812 272 HOH HOH C . Z 6 HOH 13 813 112 HOH HOH C . Z 6 HOH 14 814 156 HOH HOH C . Z 6 HOH 15 815 276 HOH HOH C . Z 6 HOH 16 816 164 HOH HOH C . Z 6 HOH 17 817 173 HOH HOH C . Z 6 HOH 18 818 176 HOH HOH C . Z 6 HOH 19 819 271 HOH HOH C . Z 6 HOH 20 820 132 HOH HOH C . Z 6 HOH 21 821 185 HOH HOH C . Z 6 HOH 22 822 72 HOH HOH C . Z 6 HOH 23 823 137 HOH HOH C . Z 6 HOH 24 824 131 HOH HOH C . Z 6 HOH 25 825 278 HOH HOH C . Z 6 HOH 26 826 288 HOH HOH C . Z 6 HOH 27 827 303 HOH HOH C . Z 6 HOH 28 828 126 HOH HOH C . Z 6 HOH 29 829 225 HOH HOH C . Z 6 HOH 30 830 114 HOH HOH C . Z 6 HOH 31 831 134 HOH HOH C . Z 6 HOH 32 832 269 HOH HOH C . Z 6 HOH 33 833 167 HOH HOH C . Z 6 HOH 34 834 113 HOH HOH C . Z 6 HOH 35 835 155 HOH HOH C . Z 6 HOH 36 836 139 HOH HOH C . Z 6 HOH 37 837 141 HOH HOH C . Z 6 HOH 38 838 175 HOH HOH C . Z 6 HOH 39 839 179 HOH HOH C . Z 6 HOH 40 840 265 HOH HOH C . Z 6 HOH 41 841 50 HOH HOH C . Z 6 HOH 42 842 154 HOH HOH C . Z 6 HOH 43 843 76 HOH HOH C . Z 6 HOH 44 844 55 HOH HOH C . Z 6 HOH 45 845 306 HOH HOH C . Z 6 HOH 46 846 273 HOH HOH C . Z 6 HOH 47 847 277 HOH HOH C . Z 6 HOH 48 848 130 HOH HOH C . Z 6 HOH 49 849 57 HOH HOH C . Z 6 HOH 50 850 149 HOH HOH C . Z 6 HOH 51 851 291 HOH HOH C . Z 6 HOH 52 852 283 HOH HOH C . Z 6 HOH 53 853 267 HOH HOH C . Z 6 HOH 54 854 147 HOH HOH C . Z 6 HOH 55 855 64 HOH HOH C . Z 6 HOH 56 856 295 HOH HOH C . Z 6 HOH 57 857 69 HOH HOH C . Z 6 HOH 58 858 118 HOH HOH C . Z 6 HOH 59 859 187 HOH HOH C . Z 6 HOH 60 860 56 HOH HOH C . Z 6 HOH 61 861 65 HOH HOH C . Z 6 HOH 62 862 49 HOH HOH C . Z 6 HOH 63 863 148 HOH HOH C . Z 6 HOH 64 864 68 HOH HOH C . Z 6 HOH 65 865 289 HOH HOH C . Z 6 HOH 66 866 282 HOH HOH C . Z 6 HOH 67 867 186 HOH HOH C . Z 6 HOH 68 868 178 HOH HOH C . Z 6 HOH 69 869 135 HOH HOH C . Z 6 HOH 70 870 160 HOH HOH C . Z 6 HOH 71 871 275 HOH HOH C . Z 6 HOH 72 872 161 HOH HOH C . Z 6 HOH 73 873 136 HOH HOH C . Z 6 HOH 74 874 67 HOH HOH C . Z 6 HOH 75 875 180 HOH HOH C . Z 6 HOH 76 876 92 HOH HOH C . Z 6 HOH 77 877 171 HOH HOH C . Z 6 HOH 78 878 163 HOH HOH C . Z 6 HOH 79 879 279 HOH HOH C . Z 6 HOH 80 880 142 HOH HOH C . Z 6 HOH 81 881 58 HOH HOH C . Z 6 HOH 82 882 287 HOH HOH C . Z 6 HOH 83 883 298 HOH HOH C . Z 6 HOH 84 884 138 HOH HOH C . Z 6 HOH 85 885 172 HOH HOH C . Z 6 HOH 86 886 177 HOH HOH C . Z 6 HOH 87 887 261 HOH HOH C . Z 6 HOH 88 888 274 HOH HOH C . Z 6 HOH 89 889 290 HOH HOH C . Z 6 HOH 90 890 162 HOH HOH C . Z 6 HOH 91 891 158 HOH HOH C . Z 6 HOH 92 892 74 HOH HOH C . Z 6 HOH 93 893 133 HOH HOH C . Z 6 HOH 94 894 152 HOH HOH C . Z 6 HOH 95 895 234 HOH HOH C . Z 6 HOH 96 896 268 HOH HOH C . Z 6 HOH 97 897 75 HOH HOH C . Z 6 HOH 98 898 297 HOH HOH C . Z 6 HOH 99 899 183 HOH HOH C . Z 6 HOH 100 900 280 HOH HOH C . Z 6 HOH 101 901 151 HOH HOH C . Z 6 HOH 102 902 296 HOH HOH C . Z 6 HOH 103 903 286 HOH HOH C . Z 6 HOH 104 904 51 HOH HOH C . Z 6 HOH 105 905 153 HOH HOH C . Z 6 HOH 106 906 305 HOH HOH C . Z 6 HOH 107 907 284 HOH HOH C . Z 6 HOH 108 908 53 HOH HOH C . Z 6 HOH 109 909 140 HOH HOH C . Z 6 HOH 110 910 70 HOH HOH C . Z 6 HOH 111 911 304 HOH HOH C . Z 6 HOH 112 912 170 HOH HOH C . Z 6 HOH 113 913 208 HOH HOH C . Z 6 HOH 114 914 146 HOH HOH C . Z 6 HOH 115 915 166 HOH HOH C . Z 6 HOH 116 916 169 HOH HOH C . Z 6 HOH 117 917 182 HOH HOH C . Z 6 HOH 118 918 181 HOH HOH C . Z 6 HOH 119 919 184 HOH HOH C . # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_defined_assembly ? monomeric 1 2 author_defined_assembly ? monomeric 1 3 author_defined_assembly ? monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,D,E,F,G,H,I,X 2 1 B,J,K,L,M,N,O,P,Y 3 1 C,Q,R,S,T,U,V,W,Z # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_special_symmetry.id _pdbx_struct_special_symmetry.PDB_model_num _pdbx_struct_special_symmetry.auth_asym_id _pdbx_struct_special_symmetry.auth_comp_id _pdbx_struct_special_symmetry.auth_seq_id _pdbx_struct_special_symmetry.PDB_ins_code _pdbx_struct_special_symmetry.label_asym_id _pdbx_struct_special_symmetry.label_comp_id _pdbx_struct_special_symmetry.label_seq_id 1 1 A HOH 807 ? X HOH . 2 1 A HOH 855 ? X HOH . # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 OD2 ? A ASP 12 ? A ASP 45 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 NE2 ? A HIS 14 ? A HIS 47 ? 1_555 114.8 ? 2 OD2 ? A ASP 12 ? A ASP 45 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 OD2 ? A ASP 77 ? A ASP 110 ? 1_555 87.4 ? 3 NE2 ? A HIS 14 ? A HIS 47 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 OD2 ? A ASP 77 ? A ASP 110 ? 1_555 87.0 ? 4 OD2 ? A ASP 12 ? A ASP 45 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 NE2 ? A HIS 262 ? A HIS 295 ? 1_555 97.6 ? 5 NE2 ? A HIS 14 ? A HIS 47 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 NE2 ? A HIS 262 ? A HIS 295 ? 1_555 95.9 ? 6 OD2 ? A ASP 77 ? A ASP 110 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 NE2 ? A HIS 262 ? A HIS 295 ? 1_555 172.5 ? 7 OD2 ? A ASP 12 ? A ASP 45 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 O6 ? I MLI . ? A MLI 706 ? 1_555 162.1 ? 8 NE2 ? A HIS 14 ? A HIS 47 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 O6 ? I MLI . ? A MLI 706 ? 1_555 82.6 ? 9 OD2 ? A ASP 77 ? A ASP 110 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 O6 ? I MLI . ? A MLI 706 ? 1_555 98.3 ? 10 NE2 ? A HIS 262 ? A HIS 295 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 O6 ? I MLI . ? A MLI 706 ? 1_555 75.3 ? 11 OD2 ? A ASP 12 ? A ASP 45 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 O7 ? I MLI . ? A MLI 706 ? 1_555 106.2 ? 12 NE2 ? A HIS 14 ? A HIS 47 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 O7 ? I MLI . ? A MLI 706 ? 1_555 132.4 ? 13 OD2 ? A ASP 77 ? A ASP 110 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 O7 ? I MLI . ? A MLI 706 ? 1_555 71.4 ? 14 NE2 ? A HIS 262 ? A HIS 295 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 O7 ? I MLI . ? A MLI 706 ? 1_555 101.8 ? 15 O6 ? I MLI . ? A MLI 706 ? 1_555 ZN ? E ZN . ? A ZN 702 ? 1_555 O7 ? I MLI . ? A MLI 706 ? 1_555 60.4 ? 16 OD2 ? A ASP 77 ? A ASP 110 ? 1_555 ZN ? D ZN . ? A ZN 701 ? 1_555 OD1 ? A ASN 118 ? A ASN 151 ? 1_555 98.3 ? 17 OD2 ? A ASP 77 ? A ASP 110 ? 1_555 ZN ? D ZN . ? A ZN 701 ? 1_555 NE2 ? A HIS 219 ? A HIS 252 ? 1_555 89.7 ? 18 OD1 ? A ASN 118 ? A ASN 151 ? 1_555 ZN ? D ZN . ? A ZN 701 ? 1_555 NE2 ? A HIS 219 ? A HIS 252 ? 1_555 92.5 ? 19 OD2 ? A ASP 77 ? A ASP 110 ? 1_555 ZN ? D ZN . ? A ZN 701 ? 1_555 ND1 ? A HIS 260 ? A HIS 293 ? 1_555 163.7 ? 20 OD1 ? A ASN 118 ? A ASN 151 ? 1_555 ZN ? D ZN . ? A ZN 701 ? 1_555 ND1 ? A HIS 260 ? A HIS 293 ? 1_555 97.7 ? 21 NE2 ? A HIS 219 ? A HIS 252 ? 1_555 ZN ? D ZN . ? A ZN 701 ? 1_555 ND1 ? A HIS 260 ? A HIS 293 ? 1_555 93.1 ? 22 OD2 ? A ASP 77 ? A ASP 110 ? 1_555 ZN ? D ZN . ? A ZN 701 ? 1_555 O7 ? I MLI . ? A MLI 706 ? 1_555 71.3 ? 23 OD1 ? A ASN 118 ? A ASN 151 ? 1_555 ZN ? D ZN . ? A ZN 701 ? 1_555 O7 ? I MLI . ? A MLI 706 ? 1_555 137.5 ? 24 NE2 ? A HIS 219 ? A HIS 252 ? 1_555 ZN ? D ZN . ? A ZN 701 ? 1_555 O7 ? I MLI . ? A MLI 706 ? 1_555 127.4 ? 25 ND1 ? A HIS 260 ? A HIS 293 ? 1_555 ZN ? D ZN . ? A ZN 701 ? 1_555 O7 ? I MLI . ? A MLI 706 ? 1_555 94.5 ? 26 OD2 ? B ASP 12 ? B ASP 45 ? 1_555 ZN ? J ZN . ? B ZN 701 ? 1_555 NE2 ? B HIS 14 ? B HIS 47 ? 1_555 119.7 ? 27 OD2 ? B ASP 12 ? B ASP 45 ? 1_555 ZN ? J ZN . ? B ZN 701 ? 1_555 OD2 ? B ASP 77 ? B ASP 110 ? 1_555 81.5 ? 28 NE2 ? B HIS 14 ? B HIS 47 ? 1_555 ZN ? J ZN . ? B ZN 701 ? 1_555 OD2 ? B ASP 77 ? B ASP 110 ? 1_555 77.5 ? 29 OD2 ? B ASP 12 ? B ASP 45 ? 1_555 ZN ? J ZN . ? B ZN 701 ? 1_555 NE2 ? B HIS 262 ? B HIS 295 ? 1_555 104.5 ? 30 NE2 ? B HIS 14 ? B HIS 47 ? 1_555 ZN ? J ZN . ? B ZN 701 ? 1_555 NE2 ? B HIS 262 ? B HIS 295 ? 1_555 108.8 ? 31 OD2 ? B ASP 77 ? B ASP 110 ? 1_555 ZN ? J ZN . ? B ZN 701 ? 1_555 NE2 ? B HIS 262 ? B HIS 295 ? 1_555 166.5 ? 32 OD2 ? B ASP 77 ? B ASP 110 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 OD1 ? B ASN 118 ? B ASN 151 ? 1_555 94.7 ? 33 OD2 ? B ASP 77 ? B ASP 110 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 NE2 ? B HIS 219 ? B HIS 252 ? 1_555 87.9 ? 34 OD1 ? B ASN 118 ? B ASN 151 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 NE2 ? B HIS 219 ? B HIS 252 ? 1_555 95.9 ? 35 OD2 ? B ASP 77 ? B ASP 110 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 ND1 ? B HIS 260 ? B HIS 293 ? 1_555 159.9 ? 36 OD1 ? B ASN 118 ? B ASN 151 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 ND1 ? B HIS 260 ? B HIS 293 ? 1_555 104.9 ? 37 NE2 ? B HIS 219 ? B HIS 252 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 ND1 ? B HIS 260 ? B HIS 293 ? 1_555 94.0 ? 38 OD2 ? B ASP 77 ? B ASP 110 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 O9 ? O MLI . ? B MLI 706 ? 1_555 103.9 ? 39 OD1 ? B ASN 118 ? B ASN 151 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 O9 ? O MLI . ? B MLI 706 ? 1_555 114.7 ? 40 NE2 ? B HIS 219 ? B HIS 252 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 O9 ? O MLI . ? B MLI 706 ? 1_555 145.6 ? 41 ND1 ? B HIS 260 ? B HIS 293 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 O9 ? O MLI . ? B MLI 706 ? 1_555 64.3 ? 42 OD2 ? B ASP 77 ? B ASP 110 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 O8 ? O MLI . ? B MLI 706 ? 1_555 51.8 ? 43 OD1 ? B ASN 118 ? B ASN 151 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 O8 ? O MLI . ? B MLI 706 ? 1_555 137.9 ? 44 NE2 ? B HIS 219 ? B HIS 252 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 O8 ? O MLI . ? B MLI 706 ? 1_555 105.9 ? 45 ND1 ? B HIS 260 ? B HIS 293 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 O8 ? O MLI . ? B MLI 706 ? 1_555 108.8 ? 46 O9 ? O MLI . ? B MLI 706 ? 1_555 ZN ? K ZN . ? B ZN 702 ? 1_555 O8 ? O MLI . ? B MLI 706 ? 1_555 61.6 ? 47 OD1 ? C ASP 12 ? C ASP 45 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 NE2 ? C HIS 14 ? C HIS 47 ? 1_555 115.8 ? 48 OD1 ? C ASP 12 ? C ASP 45 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 OD2 ? C ASP 77 ? C ASP 110 ? 1_555 97.5 ? 49 NE2 ? C HIS 14 ? C HIS 47 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 OD2 ? C ASP 77 ? C ASP 110 ? 1_555 83.3 ? 50 OD1 ? C ASP 12 ? C ASP 45 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 NE2 ? C HIS 262 ? C HIS 295 ? 1_555 90.0 ? 51 NE2 ? C HIS 14 ? C HIS 47 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 NE2 ? C HIS 262 ? C HIS 295 ? 1_555 92.4 ? 52 OD2 ? C ASP 77 ? C ASP 110 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 NE2 ? C HIS 262 ? C HIS 295 ? 1_555 172.4 ? 53 OD1 ? C ASP 12 ? C ASP 45 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 O8 ? V MLI . ? C MLI 706 ? 1_555 157.6 ? 54 NE2 ? C HIS 14 ? C HIS 47 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 O8 ? V MLI . ? C MLI 706 ? 1_555 80.4 ? 55 OD2 ? C ASP 77 ? C ASP 110 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 O8 ? V MLI . ? C MLI 706 ? 1_555 99.8 ? 56 NE2 ? C HIS 262 ? C HIS 295 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 O8 ? V MLI . ? C MLI 706 ? 1_555 73.2 ? 57 OD1 ? C ASP 12 ? C ASP 45 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 O9 ? V MLI . ? C MLI 706 ? 1_555 108.0 ? 58 NE2 ? C HIS 14 ? C HIS 47 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 O9 ? V MLI . ? C MLI 706 ? 1_555 135.9 ? 59 OD2 ? C ASP 77 ? C ASP 110 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 O9 ? V MLI . ? C MLI 706 ? 1_555 85.8 ? 60 NE2 ? C HIS 262 ? C HIS 295 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 O9 ? V MLI . ? C MLI 706 ? 1_555 93.1 ? 61 O8 ? V MLI . ? C MLI 706 ? 1_555 ZN ? Q ZN . ? C ZN 701 ? 1_555 O9 ? V MLI . ? C MLI 706 ? 1_555 59.7 ? 62 OD2 ? C ASP 77 ? C ASP 110 ? 1_555 ZN ? R ZN . ? C ZN 702 ? 1_555 OD1 ? C ASN 118 ? C ASN 151 ? 1_555 72.7 ? 63 OD2 ? C ASP 77 ? C ASP 110 ? 1_555 ZN ? R ZN . ? C ZN 702 ? 1_555 NE2 ? C HIS 219 ? C HIS 252 ? 1_555 94.5 ? 64 OD1 ? C ASN 118 ? C ASN 151 ? 1_555 ZN ? R ZN . ? C ZN 702 ? 1_555 NE2 ? C HIS 219 ? C HIS 252 ? 1_555 105.3 ? 65 OD2 ? C ASP 77 ? C ASP 110 ? 1_555 ZN ? R ZN . ? C ZN 702 ? 1_555 ND1 ? C HIS 260 ? C HIS 293 ? 1_555 171.8 ? 66 OD1 ? C ASN 118 ? C ASN 151 ? 1_555 ZN ? R ZN . ? C ZN 702 ? 1_555 ND1 ? C HIS 260 ? C HIS 293 ? 1_555 108.0 ? 67 NE2 ? C HIS 219 ? C HIS 252 ? 1_555 ZN ? R ZN . ? C ZN 702 ? 1_555 ND1 ? C HIS 260 ? C HIS 293 ? 1_555 93.2 ? 68 OD2 ? C ASP 77 ? C ASP 110 ? 1_555 ZN ? R ZN . ? C ZN 702 ? 1_555 O9 ? V MLI . ? C MLI 706 ? 1_555 82.0 ? 69 OD1 ? C ASN 118 ? C ASN 151 ? 1_555 ZN ? R ZN . ? C ZN 702 ? 1_555 O9 ? V MLI . ? C MLI 706 ? 1_555 116.7 ? 70 NE2 ? C HIS 219 ? C HIS 252 ? 1_555 ZN ? R ZN . ? C ZN 702 ? 1_555 O9 ? V MLI . ? C MLI 706 ? 1_555 134.2 ? 71 ND1 ? C HIS 260 ? C HIS 293 ? 1_555 ZN ? R ZN . ? C ZN 702 ? 1_555 O9 ? V MLI . ? C MLI 706 ? 1_555 90.5 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2016-01-20 2 'Structure model' 1 1 2016-02-03 3 'Structure model' 1 2 2016-03-30 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Database references' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0073 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS ? ? ? 10.9.5 2 ? phasing ? ? ? ? ? ? ? ? ? ? ? autoSHARP ? ? ? 2.60 3 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? 0.3.11 4 ? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot ? ? ? 0.8 5 ? 'model building' ? ? ? ? ? ? ? ? ? ? ? ARP ? ? ? 7.0 6 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 ZN B ZN 701 ? ? O8 B MLI 706 ? ? 1.51 2 1 O B ASN 69 ? ? O B HOH 801 ? ? 1.54 3 1 O B GLY 292 ? ? O B HOH 802 ? ? 1.85 4 1 OG1 B THR 377 ? ? O B HOH 803 ? ? 1.96 5 1 O B ASN 332 ? ? O B HOH 804 ? ? 2.02 6 1 CB B PRO 254 ? ? O B HOH 876 ? ? 2.06 7 1 C B HIS 252 ? ? O B HOH 809 ? ? 2.09 8 1 OE1 B GLU 371 ? ? O B HOH 805 ? ? 2.14 9 1 CG B PHE 192 ? ? O B HOH 853 ? ? 2.15 10 1 O A LEU 179 ? ? O A HOH 801 ? ? 2.15 11 1 OG1 C THR 265 ? ? O C MET 267 ? ? 2.16 12 1 OE1 B GLN 339 ? ? O B HOH 806 ? ? 2.17 13 1 OG C SER 260 ? A O C HOH 801 ? ? 2.17 14 1 OD2 B ASP 110 ? ? O8 B MLI 706 ? ? 2.18 15 1 O C ASN 217 ? ? NH2 C ARG 268 ? ? 2.19 # _pdbx_validate_rmsd_bond.id 1 _pdbx_validate_rmsd_bond.PDB_model_num 1 _pdbx_validate_rmsd_bond.auth_atom_id_1 C _pdbx_validate_rmsd_bond.auth_asym_id_1 C _pdbx_validate_rmsd_bond.auth_comp_id_1 GLY _pdbx_validate_rmsd_bond.auth_seq_id_1 109 _pdbx_validate_rmsd_bond.PDB_ins_code_1 ? _pdbx_validate_rmsd_bond.label_alt_id_1 ? _pdbx_validate_rmsd_bond.auth_atom_id_2 O _pdbx_validate_rmsd_bond.auth_asym_id_2 C _pdbx_validate_rmsd_bond.auth_comp_id_2 GLY _pdbx_validate_rmsd_bond.auth_seq_id_2 109 _pdbx_validate_rmsd_bond.PDB_ins_code_2 ? _pdbx_validate_rmsd_bond.label_alt_id_2 ? _pdbx_validate_rmsd_bond.bond_value 1.135 _pdbx_validate_rmsd_bond.bond_target_value 1.232 _pdbx_validate_rmsd_bond.bond_deviation -0.097 _pdbx_validate_rmsd_bond.bond_standard_deviation 0.016 _pdbx_validate_rmsd_bond.linker_flag N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 NE A ARG 296 ? ? CZ A ARG 296 ? ? NH1 A ARG 296 ? ? 123.73 120.30 3.43 0.50 N 2 1 NE A ARG 296 ? ? CZ A ARG 296 ? ? NH2 A ARG 296 ? ? 116.04 120.30 -4.26 0.50 N 3 1 CB A ASP 421 ? ? CG A ASP 421 ? ? OD1 A ASP 421 ? ? 123.83 118.30 5.53 0.90 N 4 1 C B PRO 34 ? ? N B PRO 35 ? ? CA B PRO 35 ? ? 129.06 119.30 9.76 1.50 Y 5 1 CB B ASP 110 ? ? CG B ASP 110 ? ? OD1 B ASP 110 ? ? 123.78 118.30 5.48 0.90 N 6 1 CB B ASP 158 ? ? CG B ASP 158 ? ? OD1 B ASP 158 ? ? 124.16 118.30 5.86 0.90 N 7 1 CB B TYR 168 ? ? CG B TYR 168 ? ? CD1 B TYR 168 ? ? 124.62 121.00 3.62 0.60 N 8 1 CA B CYS 443 ? ? CB B CYS 443 ? ? SG B CYS 443 ? ? 124.38 114.20 10.18 1.10 N 9 1 C C PRO 112 ? ? N C PRO 113 ? ? CA C PRO 113 ? ? 138.64 119.30 19.34 1.50 Y 10 1 C C PRO 112 ? ? N C PRO 113 ? ? CD C PRO 113 ? ? 110.70 128.40 -17.70 2.10 Y 11 1 NE C ARG 188 ? ? CZ C ARG 188 ? ? NH1 C ARG 188 ? ? 123.61 120.30 3.31 0.50 N 12 1 NE C ARG 204 ? ? CZ C ARG 204 ? ? NH1 C ARG 204 ? ? 123.36 120.30 3.06 0.50 N 13 1 C C LEU 258 ? ? N C PRO 259 ? ? CA C PRO 259 ? ? 109.95 119.30 -9.35 1.50 Y 14 1 CB C ASP 284 ? ? CG C ASP 284 ? ? OD2 C ASP 284 ? ? 123.87 118.30 5.57 0.90 N 15 1 NE C ARG 296 ? ? CZ C ARG 296 ? ? NH1 C ARG 296 ? ? 123.41 120.30 3.11 0.50 N 16 1 NE C ARG 296 ? ? CZ C ARG 296 ? ? NH2 C ARG 296 ? ? 116.29 120.30 -4.01 0.50 N 17 1 CB C ASP 421 ? ? CG C ASP 421 ? ? OD1 C ASP 421 ? ? 124.66 118.30 6.36 0.90 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASN A 72 ? ? -160.07 72.72 2 1 THR A 108 ? ? -96.18 35.30 3 1 ASP A 110 ? ? 59.62 74.13 4 1 ASP A 153 ? ? -87.26 44.08 5 1 ASP A 158 ? ? 78.45 -15.35 6 1 GLN A 159 ? ? -99.43 56.37 7 1 HIS A 252 ? ? -91.13 -74.04 8 1 HIS A 293 ? ? 75.23 -54.13 9 1 ASP A 382 ? ? -170.31 -168.44 10 1 SER A 417 ? ? -66.91 7.85 11 1 ASN B 72 ? ? -156.30 68.47 12 1 THR B 108 ? ? -91.92 41.34 13 1 ASP B 110 ? ? 73.09 47.63 14 1 ASP B 153 ? ? -94.18 50.07 15 1 ASP B 158 ? ? 78.06 -8.65 16 1 GLN B 159 ? ? -107.66 60.46 17 1 ASN B 209 ? ? -104.74 72.58 18 1 PRO B 216 ? ? -63.73 0.22 19 1 HIS B 252 ? ? -100.41 -72.83 20 1 ASN B 263 ? ? 58.97 9.00 21 1 HIS B 293 ? ? 84.52 -49.82 22 1 HIS B 293 ? ? 84.52 -47.25 23 1 HIS B 295 ? ? 31.66 21.52 24 1 LYS B 305 ? ? -69.00 2.92 25 1 ASP B 379 ? ? 22.65 75.31 26 1 ASP B 379 ? ? 26.47 72.21 27 1 THR B 396 ? ? -68.05 0.48 28 1 SER B 400 ? ? -46.86 107.90 29 1 SER B 417 ? ? -92.71 34.35 30 1 HIS C 47 ? ? 38.26 69.31 31 1 PRO C 50 ? ? -68.14 13.51 32 1 ASN C 72 ? ? -152.05 78.53 33 1 ASP C 110 ? ? 73.38 48.50 34 1 ASN C 142 ? ? -118.64 54.96 35 1 ASP C 153 ? ? -65.18 3.68 36 1 GLN C 157 ? ? -39.69 138.24 37 1 ASP C 158 ? ? 76.66 -11.02 38 1 GLN C 159 ? ? -97.67 47.78 39 1 ASN C 200 ? ? -154.64 76.40 40 1 ASN C 222 ? ? 58.86 9.52 41 1 ALA C 251 ? ? 179.74 170.45 42 1 HIS C 252 ? ? -76.54 -73.92 43 1 HIS C 293 ? ? 73.47 -53.37 44 1 ASP C 382 ? ? -169.52 -168.01 45 1 SER C 417 ? ? -81.97 37.60 # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C1 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id C _pdbx_validate_chiral.auth_comp_id NAG _pdbx_validate_chiral.auth_seq_id 704 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details PLANAR _pdbx_validate_chiral.omega . # loop_ _pdbx_distant_solvent_atoms.id _pdbx_distant_solvent_atoms.PDB_model_num _pdbx_distant_solvent_atoms.auth_atom_id _pdbx_distant_solvent_atoms.label_alt_id _pdbx_distant_solvent_atoms.auth_asym_id _pdbx_distant_solvent_atoms.auth_comp_id _pdbx_distant_solvent_atoms.auth_seq_id _pdbx_distant_solvent_atoms.PDB_ins_code _pdbx_distant_solvent_atoms.neighbor_macromolecule_distance _pdbx_distant_solvent_atoms.neighbor_ligand_distance 1 1 O ? B HOH 925 ? 6.18 . 2 1 O ? B HOH 926 ? 6.26 . 3 1 O ? C HOH 919 ? 5.86 . # loop_ _pdbx_audit_support.funding_organization _pdbx_audit_support.country _pdbx_audit_support.grant_number _pdbx_audit_support.ordinal 'National Research Foundation' Singapore NRF-CRP4-2008-02 1 'Swedish Cancer Society' Sweden ? 2 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 'ZINC ION' ZN 3 N-ACETYL-D-GLUCOSAMINE NAG 4 'MALONATE ION' MLI 5 GLYCEROL GOL 6 water HOH #