data_5CNI # _entry.id 5CNI # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5CNI WWPDB D_1000211902 # _pdbx_database_related.content_type unspecified _pdbx_database_related.db_id 5CNJ _pdbx_database_related.db_name PDB _pdbx_database_related.details . # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5CNI _pdbx_database_status.recvd_initial_deposition_date 2015-07-17 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Clawson, D.K.' 1 'Atwell, S.' 2 'Monn, J.A.' 3 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev J.Med.Chem. _citation.journal_id_ASTM JMCMAR _citation.journal_id_CSD 0151 _citation.journal_id_ISSN 0022-2623 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 58 _citation.language ? _citation.page_first 7526 _citation.page_last 7548 _citation.title ;Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist. ; _citation.year 2015 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1021/acs.jmedchem.5b01124 _citation.pdbx_database_id_PubMed 26313429 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Monn, J.A.' 1 primary 'Prieto, L.' 2 primary 'Taboada, L.' 3 primary 'Hao, J.' 4 primary 'Reinhard, M.R.' 5 primary 'Henry, S.S.' 6 primary 'Beadle, C.D.' 7 primary 'Walton, L.' 8 primary 'Man, T.' 9 primary 'Rudyk, H.' 10 primary 'Clark, B.' 11 primary 'Tupper, D.' 12 primary 'Baker, S.R.' 13 primary 'Lamas, C.' 14 primary 'Montero, C.' 15 primary 'Marcos, A.' 16 primary 'Blanco, J.' 17 primary 'Bures, M.' 18 primary 'Clawson, D.K.' 19 primary 'Atwell, S.' 20 primary 'Lu, F.' 21 primary 'Wang, J.' 22 primary 'Russell, M.' 23 primary 'Heinz, B.A.' 24 primary 'Wang, X.' 25 primary 'Carter, J.H.' 26 primary 'Getman, B.G.' 27 primary 'Catlow, J.T.' 28 primary 'Swanson, S.' 29 primary 'Johnson, B.G.' 30 primary 'Shaw, D.B.' 31 primary 'McKinzie, D.L.' 32 # _cell.angle_alpha 90.000 _cell.angle_alpha_esd ? _cell.angle_beta 90.000 _cell.angle_beta_esd ? _cell.angle_gamma 90.000 _cell.angle_gamma_esd ? _cell.entry_id 5CNI _cell.details ? _cell.formula_units_Z ? _cell.length_a 156.079 _cell.length_a_esd ? _cell.length_b 79.332 _cell.length_b_esd ? _cell.length_c 93.603 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 8 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 5CNI _symmetry.cell_setting ? _symmetry.Int_Tables_number 18 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'P 21 21 2' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Metabotropic glutamate receptor 2' 55712.832 2 ? ? 'UNP residues 2-493' ? 2 non-polymer syn 'GAMMA-L-GLUTAMIC ACID' 147.129 2 ? ? ? ? 3 non-polymer syn 'CHLORIDE ION' 35.453 2 ? ? ? ? 4 non-polymer syn 'SODIUM ION' 22.990 2 ? ? ? ? 5 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 4 ? ? ? ? 6 water nat water 18.015 239 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name mGluR2 # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;MALGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHL LPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLF QIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNISVATS EKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALEEVVAGSEGAAEGAITIE LASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRA LCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGL TLDTSLIPWASPSAGEGHHHHHH ; _entity_poly.pdbx_seq_one_letter_code_can ;MALGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHL LPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLF QIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNISVATS EKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALEEVVAGSEGAAEGAITIE LASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRA LCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGL TLDTSLIPWASPSAGEGHHHHHH ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 MET n 1 2 ALA n 1 3 LEU n 1 4 GLY n 1 5 SER n 1 6 LEU n 1 7 LEU n 1 8 ALA n 1 9 LEU n 1 10 LEU n 1 11 ALA n 1 12 LEU n 1 13 LEU n 1 14 LEU n 1 15 LEU n 1 16 TRP n 1 17 GLY n 1 18 ALA n 1 19 VAL n 1 20 ALA n 1 21 GLU n 1 22 GLY n 1 23 PRO n 1 24 ALA n 1 25 LYS n 1 26 LYS n 1 27 VAL n 1 28 LEU n 1 29 THR n 1 30 LEU n 1 31 GLU n 1 32 GLY n 1 33 ASP n 1 34 LEU n 1 35 VAL n 1 36 LEU n 1 37 GLY n 1 38 GLY n 1 39 LEU n 1 40 PHE n 1 41 PRO n 1 42 VAL n 1 43 HIS n 1 44 GLN n 1 45 LYS n 1 46 GLY n 1 47 GLY n 1 48 PRO n 1 49 ALA n 1 50 GLU n 1 51 ASP n 1 52 CYS n 1 53 GLY n 1 54 PRO n 1 55 VAL n 1 56 ASN n 1 57 GLU n 1 58 HIS n 1 59 ARG n 1 60 GLY n 1 61 ILE n 1 62 GLN n 1 63 ARG n 1 64 LEU n 1 65 GLU n 1 66 ALA n 1 67 MET n 1 68 LEU n 1 69 PHE n 1 70 ALA n 1 71 LEU n 1 72 ASP n 1 73 ARG n 1 74 ILE n 1 75 ASN n 1 76 ARG n 1 77 ASP n 1 78 PRO n 1 79 HIS n 1 80 LEU n 1 81 LEU n 1 82 PRO n 1 83 GLY n 1 84 VAL n 1 85 ARG n 1 86 LEU n 1 87 GLY n 1 88 ALA n 1 89 HIS n 1 90 ILE n 1 91 LEU n 1 92 ASP n 1 93 SER n 1 94 CYS n 1 95 SER n 1 96 LYS n 1 97 ASP n 1 98 THR n 1 99 HIS n 1 100 ALA n 1 101 LEU n 1 102 GLU n 1 103 GLN n 1 104 ALA n 1 105 LEU n 1 106 ASP n 1 107 PHE n 1 108 VAL n 1 109 ARG n 1 110 ALA n 1 111 SER n 1 112 LEU n 1 113 SER n 1 114 ARG n 1 115 GLY n 1 116 ALA n 1 117 ASP n 1 118 GLY n 1 119 SER n 1 120 ARG n 1 121 HIS n 1 122 ILE n 1 123 CYS n 1 124 PRO n 1 125 ASP n 1 126 GLY n 1 127 SER n 1 128 TYR n 1 129 ALA n 1 130 THR n 1 131 HIS n 1 132 GLY n 1 133 ASP n 1 134 ALA n 1 135 PRO n 1 136 THR n 1 137 ALA n 1 138 ILE n 1 139 THR n 1 140 GLY n 1 141 VAL n 1 142 ILE n 1 143 GLY n 1 144 GLY n 1 145 SER n 1 146 TYR n 1 147 SER n 1 148 ASP n 1 149 VAL n 1 150 SER n 1 151 ILE n 1 152 GLN n 1 153 VAL n 1 154 ALA n 1 155 ASN n 1 156 LEU n 1 157 LEU n 1 158 ARG n 1 159 LEU n 1 160 PHE n 1 161 GLN n 1 162 ILE n 1 163 PRO n 1 164 GLN n 1 165 ILE n 1 166 SER n 1 167 TYR n 1 168 ALA n 1 169 SER n 1 170 THR n 1 171 SER n 1 172 ALA n 1 173 LYS n 1 174 LEU n 1 175 SER n 1 176 ASP n 1 177 LYS n 1 178 SER n 1 179 ARG n 1 180 TYR n 1 181 ASP n 1 182 TYR n 1 183 PHE n 1 184 ALA n 1 185 ARG n 1 186 THR n 1 187 VAL n 1 188 PRO n 1 189 PRO n 1 190 ASP n 1 191 PHE n 1 192 PHE n 1 193 GLN n 1 194 ALA n 1 195 LYS n 1 196 ALA n 1 197 MET n 1 198 ALA n 1 199 GLU n 1 200 ILE n 1 201 LEU n 1 202 ARG n 1 203 PHE n 1 204 PHE n 1 205 ASN n 1 206 TRP n 1 207 THR n 1 208 TYR n 1 209 VAL n 1 210 SER n 1 211 THR n 1 212 VAL n 1 213 ALA n 1 214 SER n 1 215 GLU n 1 216 GLY n 1 217 ASP n 1 218 TYR n 1 219 GLY n 1 220 GLU n 1 221 THR n 1 222 GLY n 1 223 ILE n 1 224 GLU n 1 225 ALA n 1 226 PHE n 1 227 GLU n 1 228 LEU n 1 229 GLU n 1 230 ALA n 1 231 ARG n 1 232 ALA n 1 233 ARG n 1 234 ASN n 1 235 ILE n 1 236 SER n 1 237 VAL n 1 238 ALA n 1 239 THR n 1 240 SER n 1 241 GLU n 1 242 LYS n 1 243 VAL n 1 244 GLY n 1 245 ARG n 1 246 ALA n 1 247 MET n 1 248 SER n 1 249 ARG n 1 250 ALA n 1 251 ALA n 1 252 PHE n 1 253 GLU n 1 254 GLY n 1 255 VAL n 1 256 VAL n 1 257 ARG n 1 258 ALA n 1 259 LEU n 1 260 LEU n 1 261 GLN n 1 262 LYS n 1 263 PRO n 1 264 SER n 1 265 ALA n 1 266 ARG n 1 267 VAL n 1 268 ALA n 1 269 VAL n 1 270 LEU n 1 271 PHE n 1 272 THR n 1 273 ARG n 1 274 SER n 1 275 GLU n 1 276 ASP n 1 277 ALA n 1 278 ARG n 1 279 GLU n 1 280 LEU n 1 281 LEU n 1 282 ALA n 1 283 ALA n 1 284 SER n 1 285 GLN n 1 286 ARG n 1 287 LEU n 1 288 ASN n 1 289 ALA n 1 290 SER n 1 291 PHE n 1 292 THR n 1 293 TRP n 1 294 VAL n 1 295 ALA n 1 296 SER n 1 297 ASP n 1 298 GLY n 1 299 TRP n 1 300 GLY n 1 301 ALA n 1 302 LEU n 1 303 GLU n 1 304 GLU n 1 305 VAL n 1 306 VAL n 1 307 ALA n 1 308 GLY n 1 309 SER n 1 310 GLU n 1 311 GLY n 1 312 ALA n 1 313 ALA n 1 314 GLU n 1 315 GLY n 1 316 ALA n 1 317 ILE n 1 318 THR n 1 319 ILE n 1 320 GLU n 1 321 LEU n 1 322 ALA n 1 323 SER n 1 324 TYR n 1 325 PRO n 1 326 ILE n 1 327 SER n 1 328 ASP n 1 329 PHE n 1 330 ALA n 1 331 SER n 1 332 TYR n 1 333 PHE n 1 334 GLN n 1 335 SER n 1 336 LEU n 1 337 ASP n 1 338 PRO n 1 339 TRP n 1 340 ASN n 1 341 ASN n 1 342 SER n 1 343 ARG n 1 344 ASN n 1 345 PRO n 1 346 TRP n 1 347 PHE n 1 348 ARG n 1 349 GLU n 1 350 PHE n 1 351 TRP n 1 352 GLU n 1 353 GLN n 1 354 ARG n 1 355 PHE n 1 356 ARG n 1 357 CYS n 1 358 SER n 1 359 PHE n 1 360 ARG n 1 361 GLN n 1 362 ARG n 1 363 ASP n 1 364 CYS n 1 365 ALA n 1 366 ALA n 1 367 HIS n 1 368 SER n 1 369 LEU n 1 370 ARG n 1 371 ALA n 1 372 VAL n 1 373 PRO n 1 374 PHE n 1 375 GLU n 1 376 GLN n 1 377 GLU n 1 378 SER n 1 379 LYS n 1 380 ILE n 1 381 MET n 1 382 PHE n 1 383 VAL n 1 384 VAL n 1 385 ASN n 1 386 ALA n 1 387 VAL n 1 388 TYR n 1 389 ALA n 1 390 MET n 1 391 ALA n 1 392 HIS n 1 393 ALA n 1 394 LEU n 1 395 HIS n 1 396 ASN n 1 397 MET n 1 398 HIS n 1 399 ARG n 1 400 ALA n 1 401 LEU n 1 402 CYS n 1 403 PRO n 1 404 ASN n 1 405 THR n 1 406 THR n 1 407 ARG n 1 408 LEU n 1 409 CYS n 1 410 ASP n 1 411 ALA n 1 412 MET n 1 413 ARG n 1 414 PRO n 1 415 VAL n 1 416 ASN n 1 417 GLY n 1 418 ARG n 1 419 ARG n 1 420 LEU n 1 421 TYR n 1 422 LYS n 1 423 ASP n 1 424 PHE n 1 425 VAL n 1 426 LEU n 1 427 ASN n 1 428 VAL n 1 429 LYS n 1 430 PHE n 1 431 ASP n 1 432 ALA n 1 433 PRO n 1 434 PHE n 1 435 ARG n 1 436 PRO n 1 437 ALA n 1 438 ASP n 1 439 THR n 1 440 HIS n 1 441 ASN n 1 442 GLU n 1 443 VAL n 1 444 ARG n 1 445 PHE n 1 446 ASP n 1 447 ARG n 1 448 PHE n 1 449 GLY n 1 450 ASP n 1 451 GLY n 1 452 ILE n 1 453 GLY n 1 454 ARG n 1 455 TYR n 1 456 ASN n 1 457 ILE n 1 458 PHE n 1 459 THR n 1 460 TYR n 1 461 LEU n 1 462 ARG n 1 463 ALA n 1 464 GLY n 1 465 SER n 1 466 GLY n 1 467 ARG n 1 468 TYR n 1 469 ARG n 1 470 TYR n 1 471 GLN n 1 472 LYS n 1 473 VAL n 1 474 GLY n 1 475 TYR n 1 476 TRP n 1 477 ALA n 1 478 GLU n 1 479 GLY n 1 480 LEU n 1 481 THR n 1 482 LEU n 1 483 ASP n 1 484 THR n 1 485 SER n 1 486 LEU n 1 487 ILE n 1 488 PRO n 1 489 TRP n 1 490 ALA n 1 491 SER n 1 492 PRO n 1 493 SER n 1 494 ALA n 1 495 GLY n 1 496 GLU n 1 497 GLY n 1 498 HIS n 1 499 HIS n 1 500 HIS n 1 501 HIS n 1 502 HIS n 1 503 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 503 _entity_src_gen.gene_src_common_name Human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'GRM2, GPRC1B, MGLUR2' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'fall armyworm' _entity_src_gen.pdbx_host_org_scientific_name 'Spodoptera frugiperda' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7108 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line SF9 _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type BACULOVIRUS _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code GRM2_HUMAN _struct_ref.pdbx_db_accession Q14416 _struct_ref.pdbx_db_isoform ? _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;GSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPG VRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIP QISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKV GRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELAS YPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCP NTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLD TSLIPWASPSAG ; _struct_ref.pdbx_align_begin 2 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5CNI A 4 ? 495 ? Q14416 2 ? 493 ? 2 493 2 1 5CNI B 4 ? 495 ? Q14416 2 ? 493 ? 2 493 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 5CNI MET A 1 ? UNP Q14416 ? ? 'expression tag' -1 1 1 5CNI ALA A 2 ? UNP Q14416 ? ? 'expression tag' 0 2 1 5CNI LEU A 3 ? UNP Q14416 ? ? 'expression tag' 1 3 1 5CNI SER A 236 ? UNP Q14416 CYS 234 conflict 234 4 1 5CNI GLU A 304 ? UNP Q14416 SER 302 conflict 302 5 1 5CNI GLU A 496 ? UNP Q14416 ? ? 'expression tag' 494 6 1 5CNI GLY A 497 ? UNP Q14416 ? ? 'expression tag' 495 7 1 5CNI HIS A 498 ? UNP Q14416 ? ? 'expression tag' 496 8 1 5CNI HIS A 499 ? UNP Q14416 ? ? 'expression tag' 497 9 1 5CNI HIS A 500 ? UNP Q14416 ? ? 'expression tag' 498 10 1 5CNI HIS A 501 ? UNP Q14416 ? ? 'expression tag' 499 11 1 5CNI HIS A 502 ? UNP Q14416 ? ? 'expression tag' 500 12 1 5CNI HIS A 503 ? UNP Q14416 ? ? 'expression tag' 501 13 2 5CNI MET B 1 ? UNP Q14416 ? ? 'expression tag' -1 14 2 5CNI ALA B 2 ? UNP Q14416 ? ? 'expression tag' 0 15 2 5CNI LEU B 3 ? UNP Q14416 ? ? 'expression tag' 1 16 2 5CNI SER B 236 ? UNP Q14416 CYS 234 conflict 234 17 2 5CNI GLU B 304 ? UNP Q14416 SER 302 conflict 302 18 2 5CNI GLU B 496 ? UNP Q14416 ? ? 'expression tag' 494 19 2 5CNI GLY B 497 ? UNP Q14416 ? ? 'expression tag' 495 20 2 5CNI HIS B 498 ? UNP Q14416 ? ? 'expression tag' 496 21 2 5CNI HIS B 499 ? UNP Q14416 ? ? 'expression tag' 497 22 2 5CNI HIS B 500 ? UNP Q14416 ? ? 'expression tag' 498 23 2 5CNI HIS B 501 ? UNP Q14416 ? ? 'expression tag' 499 24 2 5CNI HIS B 502 ? UNP Q14416 ? ? 'expression tag' 500 25 2 5CNI HIS B 503 ? UNP Q14416 ? ? 'expression tag' 501 26 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CL non-polymer . 'CHLORIDE ION' ? 'Cl -1' 35.453 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GGL 'L-gamma-peptide, C-delta linking' . 'GAMMA-L-GLUTAMIC ACID' 'L-GLUTAMIC ACID' 'C5 H9 N O4' 147.129 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NA non-polymer . 'SODIUM ION' ? 'Na 1' 22.990 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5CNI _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.60 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 52.70 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 295 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '100mM Sodium Acetate pH 4.6 + 15% PEG 20K' _exptl_crystal_grow.pdbx_pH_range 4.6 # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'RAYONIX MX225HE' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2014-03-14 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.97931 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'APS BEAMLINE 31-ID' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.97931 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline 31-ID _diffrn_source.pdbx_synchrotron_site APS # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5CNI _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 2.69 _reflns.d_resolution_low 35.66 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 32843 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 99.47 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 7.2 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 5.3 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _refine.aniso_B[1][1] -14.5289 _refine.aniso_B[1][2] 0.0000 _refine.aniso_B[1][3] 0.0000 _refine.aniso_B[2][2] 5.9249 _refine.aniso_B[2][3] 0.0000 _refine.aniso_B[3][3] 8.6039 _refine.B_iso_max 147.450 _refine.B_iso_mean 44.3000 _refine.B_iso_min 4.410 _refine.correlation_coeff_Fo_to_Fc 0.9242 _refine.correlation_coeff_Fo_to_Fc_free 0.8805 _refine.details ? _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 5CNI _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 2.6900 _refine.ls_d_res_low 35.6600 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 32843 _refine.ls_number_reflns_R_free 1035 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 99.4700 _refine.ls_percent_reflns_R_free 3.1500 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.1699 _refine.ls_R_factor_R_free 0.2221 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.1682 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details ? _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.000 _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_method_to_determine_struct ? _refine.pdbx_starting_model ? _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI 0.2780 _refine.pdbx_overall_SU_R_free_Blow_DPI 0.2770 _refine.pdbx_overall_SU_R_Blow_DPI 0.6340 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B ? _refine.overall_SU_ML ? _refine.overall_SU_R_Cruickshank_DPI 0.5810 _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_analyze.entry_id 5CNI _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_analyze.Luzzati_coordinate_error_free ? _refine_analyze.Luzzati_coordinate_error_obs 0.262 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.Luzzati_d_res_low_obs ? _refine_analyze.Luzzati_sigma_a_free ? _refine_analyze.Luzzati_sigma_a_free_details ? _refine_analyze.Luzzati_sigma_a_obs ? _refine_analyze.Luzzati_sigma_a_obs_details ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.RG_d_res_high ? _refine_analyze.RG_d_res_low ? _refine_analyze.RG_free ? _refine_analyze.RG_work ? _refine_analyze.RG_free_work_ratio ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? # _refine_hist.cycle_id final _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.d_res_high 2.6900 _refine_hist.d_res_low 35.6600 _refine_hist.pdbx_number_atoms_ligand 80 _refine_hist.number_atoms_solvent 239 _refine_hist.number_atoms_total 7131 _refine_hist.pdbx_number_residues_total 876 _refine_hist.pdbx_B_iso_mean_ligand 76.73 _refine_hist.pdbx_B_iso_mean_solvent 41.68 _refine_hist.pdbx_number_atoms_protein 6812 _refine_hist.pdbx_number_atoms_nucleic_acid 0 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.criterion _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.rejects _refine_ls_restr.type _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' ? ? ? 2373 ? t_dihedral_angle_d 2.000 SINUSOIDAL 'X-RAY DIFFRACTION' ? ? ? 153 ? t_trig_c_planes 2.000 HARMONIC 'X-RAY DIFFRACTION' ? ? ? 1065 ? t_gen_planes 5.000 HARMONIC 'X-RAY DIFFRACTION' ? ? ? 7059 ? t_it 20.000 HARMONIC 'X-RAY DIFFRACTION' ? ? ? 3 ? t_nbd 5.000 SEMIHARMONIC 'X-RAY DIFFRACTION' ? ? ? ? ? t_improper_torsion ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_pseud_angle ? ? 'X-RAY DIFFRACTION' ? ? ? 909 ? t_chiral_improper_torsion 5.000 SEMIHARMONIC 'X-RAY DIFFRACTION' ? ? ? ? ? t_sum_occupancies ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_utility_distance ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_utility_angle ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_utility_torsion ? ? 'X-RAY DIFFRACTION' ? ? ? 8140 ? t_ideal_dist_contact 4.000 SEMIHARMONIC 'X-RAY DIFFRACTION' ? 0.010 ? 7059 ? t_bond_d 2.000 HARMONIC 'X-RAY DIFFRACTION' ? 1.100 ? 9584 ? t_angle_deg 2.000 HARMONIC 'X-RAY DIFFRACTION' ? 3.080 ? ? ? t_omega_torsion ? ? 'X-RAY DIFFRACTION' ? 18.200 ? ? ? t_other_torsion ? ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.d_res_high 2.6900 _refine_ls_shell.d_res_low 2.7800 _refine_ls_shell.number_reflns_all 2855 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.number_reflns_R_free 86 _refine_ls_shell.number_reflns_R_work 2769 _refine_ls_shell.percent_reflns_obs 99.4700 _refine_ls_shell.percent_reflns_R_free 3.0100 _refine_ls_shell.R_factor_all 0.1919 _refine_ls_shell.R_factor_obs ? _refine_ls_shell.R_factor_R_free 0.3095 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.R_factor_R_work 0.1885 _refine_ls_shell.redundancy_reflns_all ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.wR_factor_all ? _refine_ls_shell.wR_factor_obs ? _refine_ls_shell.wR_factor_R_free ? _refine_ls_shell.wR_factor_R_work ? _refine_ls_shell.pdbx_total_number_of_bins_used 16 _refine_ls_shell.pdbx_phase_error ? _refine_ls_shell.pdbx_fsc_work ? _refine_ls_shell.pdbx_fsc_free ? # _struct.entry_id 5CNI _struct.title 'mGlu2 with Glutamate' _struct.pdbx_descriptor 'Metabotropic glutamate receptor 2' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5CNI _struct_keywords.text 'receptor, glutamate, metabotropic, SIGNALING PROTEIN' _struct_keywords.pdbx_keywords 'SIGNALING PROTEIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 3 ? E N N 4 ? F N N 5 ? G N N 5 ? H N N 2 ? I N N 3 ? J N N 4 ? K N N 5 ? L N N 5 ? M N N 6 ? N N N 6 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 GLY A 60 ? ASN A 75 ? GLY A 58 ASN A 73 1 ? 16 HELX_P HELX_P2 AA2 LYS A 96 ? ARG A 109 ? LYS A 94 ARG A 107 1 ? 14 HELX_P HELX_P3 AA3 TYR A 146 ? ARG A 158 ? TYR A 144 ARG A 156 1 ? 13 HELX_P HELX_P4 AA4 LEU A 159 ? GLN A 161 ? LEU A 157 GLN A 159 5 ? 3 HELX_P HELX_P5 AA5 SER A 171 ? ASP A 176 ? SER A 169 ASP A 174 5 ? 6 HELX_P HELX_P6 AA6 ASP A 190 ? PHE A 204 ? ASP A 188 PHE A 202 1 ? 15 HELX_P HELX_P7 AA7 TYR A 218 ? ALA A 232 ? TYR A 216 ALA A 230 1 ? 15 HELX_P HELX_P8 AA8 SER A 248 ? GLN A 261 ? SER A 246 GLN A 259 1 ? 14 HELX_P HELX_P9 AA9 ARG A 273 ? LEU A 287 ? ARG A 271 LEU A 285 1 ? 15 HELX_P HELX_P10 AB1 LEU A 302 ? ALA A 307 ? LEU A 300 ALA A 305 1 ? 6 HELX_P HELX_P11 AB2 SER A 309 ? GLU A 314 ? SER A 307 GLU A 312 1 ? 6 HELX_P HELX_P12 AB3 ILE A 326 ? SER A 335 ? ILE A 324 SER A 333 1 ? 10 HELX_P HELX_P13 AB4 TRP A 346 ? ARG A 356 ? TRP A 344 ARG A 354 1 ? 11 HELX_P HELX_P14 AB5 LYS A 379 ? CYS A 402 ? LYS A 377 CYS A 400 1 ? 24 HELX_P HELX_P15 AB6 CYS A 409 ? ARG A 413 ? CYS A 407 ARG A 411 5 ? 5 HELX_P HELX_P16 AB7 ASN A 416 ? PHE A 424 ? ASN A 414 PHE A 422 1 ? 9 HELX_P HELX_P17 AB8 VAL A 425 ? VAL A 428 ? VAL A 423 VAL A 426 5 ? 4 HELX_P HELX_P18 AB9 GLY B 60 ? ASN B 75 ? GLY B 58 ASN B 73 1 ? 16 HELX_P HELX_P19 AC1 LYS B 96 ? ARG B 109 ? LYS B 94 ARG B 107 1 ? 14 HELX_P HELX_P20 AC2 TYR B 146 ? ARG B 158 ? TYR B 144 ARG B 156 1 ? 13 HELX_P HELX_P21 AC3 LEU B 159 ? GLN B 161 ? LEU B 157 GLN B 159 5 ? 3 HELX_P HELX_P22 AC4 SER B 171 ? ASP B 176 ? SER B 169 ASP B 174 5 ? 6 HELX_P HELX_P23 AC5 PRO B 189 ? PHE B 204 ? PRO B 187 PHE B 202 1 ? 16 HELX_P HELX_P24 AC6 TYR B 218 ? ALA B 232 ? TYR B 216 ALA B 230 1 ? 15 HELX_P HELX_P25 AC7 SER B 248 ? GLN B 261 ? SER B 246 GLN B 259 1 ? 14 HELX_P HELX_P26 AC8 ARG B 273 ? LEU B 287 ? ARG B 271 LEU B 285 1 ? 15 HELX_P HELX_P27 AC9 LEU B 302 ? ALA B 307 ? LEU B 300 ALA B 305 1 ? 6 HELX_P HELX_P28 AD1 SER B 309 ? GLU B 314 ? SER B 307 GLU B 312 1 ? 6 HELX_P HELX_P29 AD2 ILE B 326 ? SER B 335 ? ILE B 324 SER B 333 1 ? 10 HELX_P HELX_P30 AD3 TRP B 346 ? PHE B 355 ? TRP B 344 PHE B 353 1 ? 10 HELX_P HELX_P31 AD4 LYS B 379 ? CYS B 402 ? LYS B 377 CYS B 400 1 ? 24 HELX_P HELX_P32 AD5 CYS B 409 ? ARG B 413 ? CYS B 407 ARG B 411 5 ? 5 HELX_P HELX_P33 AD6 ASN B 416 ? PHE B 424 ? ASN B 414 PHE B 422 1 ? 9 HELX_P HELX_P34 AD7 VAL B 425 ? VAL B 428 ? VAL B 423 VAL B 426 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 52 SG ? ? ? 1_555 A CYS 94 SG ? ? A CYS 50 A CYS 92 1_555 ? ? ? ? ? ? ? 2.030 ? disulf2 disulf ? ? A CYS 357 SG ? ? ? 1_555 A CYS 364 SG ? ? A CYS 355 A CYS 362 1_555 ? ? ? ? ? ? ? 2.047 ? disulf3 disulf ? ? A CYS 402 SG ? ? ? 1_555 A CYS 409 SG ? ? A CYS 400 A CYS 407 1_555 ? ? ? ? ? ? ? 2.051 ? disulf4 disulf ? ? B CYS 52 SG ? ? ? 1_555 B CYS 94 SG ? ? B CYS 50 B CYS 92 1_555 ? ? ? ? ? ? ? 2.037 ? disulf5 disulf ? ? B CYS 357 SG ? ? ? 1_555 B CYS 364 SG ? ? B CYS 355 B CYS 362 1_555 ? ? ? ? ? ? ? 2.065 ? disulf6 disulf ? ? B CYS 402 SG ? ? ? 1_555 B CYS 409 SG ? ? B CYS 400 B CYS 407 1_555 ? ? ? ? ? ? ? 2.053 ? metalc1 metalc ? ? A ILE 74 O ? ? ? 1_555 E NA . NA ? ? A ILE 72 A NA 603 1_555 ? ? ? ? ? ? ? 2.573 ? metalc2 metalc ? ? A ASP 77 O ? ? ? 1_555 E NA . NA ? ? A ASP 75 A NA 603 1_555 ? ? ? ? ? ? ? 2.609 ? metalc3 metalc ? ? A LEU 80 O ? ? ? 1_555 E NA . NA ? ? A LEU 78 A NA 603 1_555 ? ? ? ? ? ? ? 2.698 ? metalc4 metalc ? ? A LEU 81 O ? ? ? 1_555 E NA . NA ? ? A LEU 79 A NA 603 1_555 ? ? ? ? ? ? ? 3.081 ? covale1 covale one ? A ASN 205 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 203 A NAG 604 1_555 ? ? ? ? ? ? ? 1.435 ? covale2 covale one ? A ASN 288 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 286 A NAG 605 1_555 ? ? ? ? ? ? ? 1.435 ? metalc5 metalc ? ? B ILE 74 O ? ? ? 1_555 J NA . NA ? ? B ILE 72 B NA 603 1_555 ? ? ? ? ? ? ? 2.235 ? metalc6 metalc ? ? B LEU 80 O ? ? ? 1_555 J NA . NA ? ? B LEU 78 B NA 603 1_555 ? ? ? ? ? ? ? 2.240 ? metalc7 metalc ? ? B LEU 81 O ? ? ? 1_555 J NA . NA ? ? B LEU 79 B NA 603 1_555 ? ? ? ? ? ? ? 2.582 ? covale3 covale one ? B ASN 205 ND2 ? ? ? 1_555 K NAG . C1 ? ? B ASN 203 B NAG 604 1_555 ? ? ? ? ? ? ? 1.435 ? covale4 covale one ? B ASN 288 ND2 ? ? ? 1_555 L NAG . C1 ? ? B ASN 286 B NAG 605 1_555 ? ? ? ? ? ? ? 1.435 ? metalc8 metalc ? ? E NA . NA ? ? ? 1_555 M HOH . O ? ? A NA 603 A HOH 754 1_555 ? ? ? ? ? ? ? 2.465 ? metalc9 metalc ? ? J NA . NA ? ? ? 1_555 N HOH . O ? ? B NA 603 B HOH 714 1_555 ? ? ? ? ? ? ? 2.261 ? metalc10 metalc ? ? J NA . NA ? ? ? 1_555 N HOH . O ? ? B NA 603 B HOH 708 1_555 ? ? ? ? ? ? ? 2.238 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLY 143 A . ? GLY 141 A GLY 144 A ? GLY 142 A 1 -2.98 2 ARG 413 A . ? ARG 411 A PRO 414 A ? PRO 412 A 1 2.39 3 GLY 143 B . ? GLY 141 B GLY 144 B ? GLY 142 B 1 -3.05 4 ARG 413 B . ? ARG 411 B PRO 414 B ? PRO 412 B 1 -0.48 5 GLY 466 B . ? GLY 464 B ARG 467 B ? ARG 465 B 1 -3.26 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 6 ? AA2 ? 2 ? AA3 ? 8 ? AA4 ? 2 ? AA5 ? 6 ? AA6 ? 2 ? AA7 ? 7 ? AA8 ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? parallel AA1 3 4 ? parallel AA1 4 5 ? parallel AA1 5 6 ? parallel AA2 1 2 ? anti-parallel AA3 1 2 ? parallel AA3 2 3 ? parallel AA3 3 4 ? parallel AA3 4 5 ? parallel AA3 5 6 ? anti-parallel AA3 6 7 ? anti-parallel AA3 7 8 ? anti-parallel AA4 1 2 ? anti-parallel AA5 1 2 ? anti-parallel AA5 2 3 ? parallel AA5 3 4 ? parallel AA5 4 5 ? parallel AA5 5 6 ? parallel AA6 1 2 ? anti-parallel AA7 1 2 ? parallel AA7 2 3 ? parallel AA7 3 4 ? parallel AA7 4 5 ? parallel AA7 5 6 ? anti-parallel AA7 6 7 ? anti-parallel AA8 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 LEU A 28 ? LEU A 30 ? LEU A 26 LEU A 28 AA1 2 LEU A 86 ? ASP A 92 ? LEU A 84 ASP A 90 AA1 3 LEU A 34 ? PHE A 40 ? LEU A 32 PHE A 38 AA1 4 GLY A 140 ? ILE A 142 ? GLY A 138 ILE A 140 AA1 5 GLN A 164 ? SER A 166 ? GLN A 162 SER A 164 AA1 6 PHE A 183 ? ARG A 185 ? PHE A 181 ARG A 183 AA2 1 HIS A 43 ? LYS A 45 ? HIS A 41 LYS A 43 AA2 2 CYS A 52 ? VAL A 55 ? CYS A 50 VAL A 53 AA3 1 SER A 236 ? VAL A 243 ? SER A 234 VAL A 241 AA3 2 TYR A 208 ? SER A 214 ? TYR A 206 SER A 212 AA3 3 VAL A 267 ? PHE A 271 ? VAL A 265 PHE A 269 AA3 4 THR A 292 ? ALA A 295 ? THR A 290 ALA A 293 AA3 5 ILE A 317 ? LEU A 321 ? ILE A 315 LEU A 319 AA3 6 ARG A 454 ? ARG A 462 ? ARG A 452 ARG A 460 AA3 7 TYR A 468 ? ALA A 477 ? TYR A 466 ALA A 475 AA3 8 LEU A 480 ? LEU A 482 ? LEU A 478 LEU A 480 AA4 1 PHE A 430 ? ASP A 431 ? PHE A 428 ASP A 429 AA4 2 GLU A 442 ? VAL A 443 ? GLU A 440 VAL A 441 AA5 1 LEU B 28 ? LEU B 30 ? LEU B 26 LEU B 28 AA5 2 LEU B 86 ? ASP B 92 ? LEU B 84 ASP B 90 AA5 3 LEU B 34 ? PHE B 40 ? LEU B 32 PHE B 38 AA5 4 ILE B 138 ? ILE B 142 ? ILE B 136 ILE B 140 AA5 5 GLN B 164 ? SER B 166 ? GLN B 162 SER B 164 AA5 6 PHE B 183 ? ARG B 185 ? PHE B 181 ARG B 183 AA6 1 HIS B 43 ? LYS B 45 ? HIS B 41 LYS B 43 AA6 2 CYS B 52 ? VAL B 55 ? CYS B 50 VAL B 53 AA7 1 SER B 236 ? VAL B 243 ? SER B 234 VAL B 241 AA7 2 TYR B 208 ? SER B 214 ? TYR B 206 SER B 212 AA7 3 VAL B 267 ? PHE B 271 ? VAL B 265 PHE B 269 AA7 4 THR B 292 ? ALA B 295 ? THR B 290 ALA B 293 AA7 5 ILE B 317 ? LEU B 321 ? ILE B 315 LEU B 319 AA7 6 ARG B 454 ? ARG B 462 ? ARG B 452 ARG B 460 AA7 7 TYR B 468 ? ALA B 477 ? TYR B 466 ALA B 475 AA8 1 PHE B 430 ? ASP B 431 ? PHE B 428 ASP B 429 AA8 2 GLU B 442 ? VAL B 443 ? GLU B 440 VAL B 441 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N LEU A 28 ? N LEU A 26 O ILE A 90 ? O ILE A 88 AA1 2 3 O GLY A 87 ? O GLY A 85 N LEU A 34 ? N LEU A 32 AA1 3 4 N GLY A 37 ? N GLY A 35 O GLY A 140 ? O GLY A 138 AA1 4 5 N VAL A 141 ? N VAL A 139 O ILE A 165 ? O ILE A 163 AA1 5 6 N GLN A 164 ? N GLN A 162 O ALA A 184 ? O ALA A 182 AA2 1 2 N GLN A 44 ? N GLN A 42 O GLY A 53 ? O GLY A 51 AA3 1 2 O ALA A 238 ? O ALA A 236 N VAL A 209 ? N VAL A 207 AA3 2 3 N SER A 210 ? N SER A 208 O VAL A 269 ? O VAL A 267 AA3 3 4 N LEU A 270 ? N LEU A 268 O VAL A 294 ? O VAL A 292 AA3 4 5 N TRP A 293 ? N TRP A 291 O ILE A 317 ? O ILE A 315 AA3 5 6 N GLU A 320 ? N GLU A 318 O ASN A 456 ? O ASN A 454 AA3 6 7 N LEU A 461 ? N LEU A 459 O ARG A 469 ? O ARG A 467 AA3 7 8 N TYR A 475 ? N TYR A 473 O THR A 481 ? O THR A 479 AA4 1 2 N PHE A 430 ? N PHE A 428 O VAL A 443 ? O VAL A 441 AA5 1 2 N LEU B 30 ? N LEU B 28 O ALA B 88 ? O ALA B 86 AA5 2 3 O GLY B 87 ? O GLY B 85 N LEU B 34 ? N LEU B 32 AA5 3 4 N GLY B 37 ? N GLY B 35 O GLY B 140 ? O GLY B 138 AA5 4 5 N VAL B 141 ? N VAL B 139 O ILE B 165 ? O ILE B 163 AA5 5 6 N GLN B 164 ? N GLN B 162 O ALA B 184 ? O ALA B 182 AA6 1 2 N GLN B 44 ? N GLN B 42 O PRO B 54 ? O PRO B 52 AA7 1 2 O ALA B 238 ? O ALA B 236 N VAL B 209 ? N VAL B 207 AA7 2 3 N SER B 210 ? N SER B 208 O VAL B 267 ? O VAL B 265 AA7 3 4 N LEU B 270 ? N LEU B 268 O VAL B 294 ? O VAL B 292 AA7 4 5 N TRP B 293 ? N TRP B 291 O ILE B 317 ? O ILE B 315 AA7 5 6 N GLU B 320 ? N GLU B 318 O ASN B 456 ? O ASN B 454 AA7 6 7 N TYR B 455 ? N TYR B 453 O TRP B 476 ? O TRP B 474 AA8 1 2 N PHE B 430 ? N PHE B 428 O VAL B 443 ? O VAL B 441 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A GGL 601 ? 11 'binding site for residue GGL A 601' AC2 Software A CL 602 ? 4 'binding site for residue CL A 602' AC3 Software A NA 603 ? 5 'binding site for residue NA A 603' AC4 Software B GGL 601 ? 10 'binding site for residue GGL B 601' AC5 Software B CL 602 ? 3 'binding site for residue CL B 602' AC6 Software B NA 603 ? 6 'binding site for residue NA B 603' AC7 Software A NAG 604 ? 2 'binding site for Mono-Saccharide NAG A 604 bound to ASN A 203' AC8 Software A NAG 605 ? 3 'binding site for Mono-Saccharide NAG A 605 bound to ASN A 286' AC9 Software B NAG 604 ? 2 'binding site for Mono-Saccharide NAG B 604 bound to ASN B 203' AD1 Software B NAG 605 ? 1 'binding site for Mono-Saccharide NAG B 605 bound to ASN B 286' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 11 ARG A 59 ? ARG A 57 . ? 1_555 ? 2 AC1 11 ARG A 63 ? ARG A 61 . ? 1_555 ? 3 AC1 11 SER A 145 ? SER A 143 . ? 1_555 ? 4 AC1 11 TYR A 146 ? TYR A 144 . ? 1_555 ? 5 AC1 11 SER A 147 ? SER A 145 . ? 1_555 ? 6 AC1 11 ALA A 168 ? ALA A 166 . ? 1_555 ? 7 AC1 11 SER A 169 ? SER A 167 . ? 1_555 ? 8 AC1 11 THR A 170 ? THR A 168 . ? 1_555 ? 9 AC1 11 TYR A 218 ? TYR A 216 . ? 1_555 ? 10 AC1 11 ASP A 297 ? ASP A 295 . ? 1_555 ? 11 AC1 11 LYS A 379 ? LYS A 377 . ? 1_555 ? 12 AC2 4 SER A 93 ? SER A 91 . ? 1_555 ? 13 AC2 4 SER A 145 ? SER A 143 . ? 1_555 ? 14 AC2 4 TYR A 146 ? TYR A 144 . ? 1_555 ? 15 AC2 4 VAL A 149 ? VAL A 147 . ? 1_555 ? 16 AC3 5 ILE A 74 ? ILE A 72 . ? 1_555 ? 17 AC3 5 ASP A 77 ? ASP A 75 . ? 1_555 ? 18 AC3 5 LEU A 80 ? LEU A 78 . ? 1_555 ? 19 AC3 5 LEU A 81 ? LEU A 79 . ? 1_555 ? 20 AC3 5 HOH M . ? HOH A 754 . ? 1_555 ? 21 AC4 10 ARG B 59 ? ARG B 57 . ? 1_555 ? 22 AC4 10 ARG B 63 ? ARG B 61 . ? 1_555 ? 23 AC4 10 TYR B 146 ? TYR B 144 . ? 1_555 ? 24 AC4 10 SER B 147 ? SER B 145 . ? 1_555 ? 25 AC4 10 ALA B 168 ? ALA B 166 . ? 1_555 ? 26 AC4 10 SER B 169 ? SER B 167 . ? 1_555 ? 27 AC4 10 THR B 170 ? THR B 168 . ? 1_555 ? 28 AC4 10 TYR B 218 ? TYR B 216 . ? 1_555 ? 29 AC4 10 ASP B 297 ? ASP B 295 . ? 1_555 ? 30 AC4 10 LYS B 379 ? LYS B 377 . ? 1_555 ? 31 AC5 3 SER B 93 ? SER B 91 . ? 1_555 ? 32 AC5 3 SER B 145 ? SER B 143 . ? 1_555 ? 33 AC5 3 VAL B 149 ? VAL B 147 . ? 1_555 ? 34 AC6 6 ILE B 74 ? ILE B 72 . ? 1_555 ? 35 AC6 6 ASP B 77 ? ASP B 75 . ? 1_555 ? 36 AC6 6 LEU B 80 ? LEU B 78 . ? 1_555 ? 37 AC6 6 LEU B 81 ? LEU B 79 . ? 1_555 ? 38 AC6 6 HOH N . ? HOH B 708 . ? 1_555 ? 39 AC6 6 HOH N . ? HOH B 714 . ? 1_555 ? 40 AC7 2 PHE A 203 ? PHE A 201 . ? 1_555 ? 41 AC7 2 ASN A 205 ? ASN A 203 . ? 1_555 ? 42 AC8 3 ASN A 288 ? ASN A 286 . ? 1_555 ? 43 AC8 3 HOH M . ? HOH A 779 . ? 1_555 ? 44 AC8 3 ARG B 419 ? ARG B 417 . ? 3_756 ? 45 AC9 2 PHE B 203 ? PHE B 201 . ? 1_555 ? 46 AC9 2 ASN B 205 ? ASN B 203 . ? 1_555 ? 47 AD1 1 ASN B 288 ? ASN B 286 . ? 1_555 ? # _atom_sites.entry_id 5CNI _atom_sites.fract_transf_matrix[1][1] 0.006407 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.012605 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.010683 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CL N NA O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . LYS A 1 25 ? 175.932 75.892 38.474 1.00 62.37 ? 23 LYS A N 1 ATOM 2 C CA . LYS A 1 25 ? 174.566 75.709 38.987 1.00 62.30 ? 23 LYS A CA 1 ATOM 3 C C . LYS A 1 25 ? 173.526 76.670 38.352 1.00 64.47 ? 23 LYS A C 1 ATOM 4 O O . LYS A 1 25 ? 172.603 76.205 37.673 1.00 63.78 ? 23 LYS A O 1 ATOM 5 C CB . LYS A 1 25 ? 174.528 75.787 40.534 1.00 64.88 ? 23 LYS A CB 1 ATOM 6 N N . LYS A 1 26 ? 173.678 78.000 38.583 1.00 59.09 ? 24 LYS A N 1 ATOM 7 C CA . LYS A 1 26 ? 172.757 79.028 38.079 1.00 57.48 ? 24 LYS A CA 1 ATOM 8 C C . LYS A 1 26 ? 172.926 79.281 36.586 1.00 58.17 ? 24 LYS A C 1 ATOM 9 O O . LYS A 1 26 ? 174.010 79.101 36.024 1.00 57.26 ? 24 LYS A O 1 ATOM 10 C CB . LYS A 1 26 ? 172.876 80.343 38.878 1.00 59.61 ? 24 LYS A CB 1 ATOM 11 C CG . LYS A 1 26 ? 172.341 80.268 40.308 1.00 71.04 ? 24 LYS A CG 1 ATOM 12 C CD . LYS A 1 26 ? 172.668 81.527 41.139 1.00 83.08 ? 24 LYS A CD 1 ATOM 13 C CE . LYS A 1 26 ? 174.013 81.466 41.849 1.00 95.73 ? 24 LYS A CE 1 ATOM 14 N NZ . LYS A 1 26 ? 174.325 82.707 42.620 1.00 100.01 ? 24 LYS A NZ 1 ATOM 15 N N . VAL A 1 27 ? 171.828 79.691 35.956 1.00 52.97 ? 25 VAL A N 1 ATOM 16 C CA . VAL A 1 27 ? 171.714 80.019 34.531 1.00 51.68 ? 25 VAL A CA 1 ATOM 17 C C . VAL A 1 27 ? 170.845 81.284 34.394 1.00 51.55 ? 25 VAL A C 1 ATOM 18 O O . VAL A 1 27 ? 169.868 81.443 35.137 1.00 51.81 ? 25 VAL A O 1 ATOM 19 C CB . VAL A 1 27 ? 171.220 78.818 33.643 1.00 55.63 ? 25 VAL A CB 1 ATOM 20 C CG1 . VAL A 1 27 ? 170.019 78.108 34.252 1.00 55.89 ? 25 VAL A CG1 1 ATOM 21 C CG2 . VAL A 1 27 ? 170.896 79.256 32.217 1.00 55.39 ? 25 VAL A CG2 1 ATOM 22 N N . LEU A 1 28 ? 171.248 82.198 33.484 1.00 43.85 ? 26 LEU A N 1 ATOM 23 C CA . LEU A 1 28 ? 170.543 83.434 33.181 1.00 41.18 ? 26 LEU A CA 1 ATOM 24 C C . LEU A 1 28 ? 169.729 83.147 31.950 1.00 45.44 ? 26 LEU A C 1 ATOM 25 O O . LEU A 1 28 ? 170.276 82.963 30.868 1.00 45.14 ? 26 LEU A O 1 ATOM 26 C CB . LEU A 1 28 ? 171.531 84.567 32.912 1.00 40.22 ? 26 LEU A CB 1 ATOM 27 C CG . LEU A 1 28 ? 170.999 85.996 32.950 1.00 43.59 ? 26 LEU A CG 1 ATOM 28 C CD1 . LEU A 1 28 ? 172.102 86.952 33.172 1.00 43.05 ? 26 LEU A CD1 1 ATOM 29 C CD2 . LEU A 1 28 ? 170.290 86.386 31.671 1.00 45.22 ? 26 LEU A CD2 1 ATOM 30 N N . THR A 1 29 ? 168.420 83.078 32.126 1.00 42.92 ? 27 THR A N 1 ATOM 31 C CA . THR A 1 29 ? 167.475 82.843 31.051 1.00 42.55 ? 27 THR A CA 1 ATOM 32 C C . THR A 1 29 ? 166.663 84.107 30.867 1.00 45.23 ? 27 THR A C 1 ATOM 33 O O . THR A 1 29 ? 166.302 84.753 31.850 1.00 45.30 ? 27 THR A O 1 ATOM 34 C CB . THR A 1 29 ? 166.634 81.591 31.351 1.00 53.35 ? 27 THR A CB 1 ATOM 35 O OG1 . THR A 1 29 ? 167.415 80.447 31.028 1.00 53.10 ? 27 THR A OG1 1 ATOM 36 C CG2 . THR A 1 29 ? 165.329 81.529 30.552 1.00 53.88 ? 27 THR A CG2 1 ATOM 37 N N . LEU A 1 30 ? 166.440 84.470 29.601 1.00 40.52 ? 28 LEU A N 1 ATOM 38 C CA . LEU A 1 30 ? 165.621 85.566 29.103 1.00 40.20 ? 28 LEU A CA 1 ATOM 39 C C . LEU A 1 30 ? 164.900 84.960 27.916 1.00 45.26 ? 28 LEU A C 1 ATOM 40 O O . LEU A 1 30 ? 165.517 84.241 27.123 1.00 45.07 ? 28 LEU A O 1 ATOM 41 C CB . LEU A 1 30 ? 166.453 86.778 28.649 1.00 40.09 ? 28 LEU A CB 1 ATOM 42 C CG . LEU A 1 30 ? 167.322 87.493 29.677 1.00 45.14 ? 28 LEU A CG 1 ATOM 43 C CD1 . LEU A 1 30 ? 167.915 88.734 29.072 1.00 45.67 ? 28 LEU A CD1 1 ATOM 44 C CD2 . LEU A 1 30 ? 166.550 87.870 30.941 1.00 46.76 ? 28 LEU A CD2 1 ATOM 45 N N . GLU A 1 31 ? 163.598 85.226 27.800 1.00 42.33 ? 29 GLU A N 1 ATOM 46 C CA . GLU A 1 31 ? 162.770 84.620 26.760 1.00 41.69 ? 29 GLU A CA 1 ATOM 47 C C . GLU A 1 31 ? 162.727 85.431 25.453 1.00 41.37 ? 29 GLU A C 1 ATOM 48 O O . GLU A 1 31 ? 162.873 86.657 25.461 1.00 40.98 ? 29 GLU A O 1 ATOM 49 C CB . GLU A 1 31 ? 161.358 84.313 27.309 1.00 43.59 ? 29 GLU A CB 1 ATOM 50 C CG . GLU A 1 31 ? 161.367 83.227 28.391 1.00 61.56 ? 29 GLU A CG 1 ATOM 51 C CD . GLU A 1 31 ? 160.039 82.846 29.033 1.00 100.41 ? 29 GLU A CD 1 ATOM 52 O OE1 . GLU A 1 31 ? 159.730 81.632 29.069 1.00 99.73 ? 29 GLU A OE1 1 ATOM 53 O OE2 . GLU A 1 31 ? 159.329 83.748 29.538 1.00 101.43 ? 29 GLU A OE2 1 ATOM 54 N N . GLY A 1 32 ? 162.545 84.713 24.347 1.00 34.45 ? 30 GLY A N 1 ATOM 55 C CA . GLY A 1 32 ? 162.443 85.272 23.007 1.00 33.06 ? 30 GLY A CA 1 ATOM 56 C C . GLY A 1 32 ? 162.242 84.221 21.935 1.00 37.55 ? 30 GLY A C 1 ATOM 57 O O . GLY A 1 32 ? 162.444 83.028 22.170 1.00 36.12 ? 30 GLY A O 1 ATOM 58 N N . ASP A 1 33 ? 161.891 84.676 20.725 1.00 36.77 ? 31 ASP A N 1 ATOM 59 C CA . ASP A 1 33 ? 161.664 83.875 19.508 1.00 36.57 ? 31 ASP A CA 1 ATOM 60 C C . ASP A 1 33 ? 162.918 83.116 19.076 1.00 38.32 ? 31 ASP A C 1 ATOM 61 O O . ASP A 1 33 ? 162.811 81.983 18.612 1.00 38.11 ? 31 ASP A O 1 ATOM 62 C CB . ASP A 1 33 ? 161.168 84.798 18.378 1.00 38.82 ? 31 ASP A CB 1 ATOM 63 C CG . ASP A 1 33 ? 159.992 85.657 18.803 1.00 50.29 ? 31 ASP A CG 1 ATOM 64 O OD1 . ASP A 1 33 ? 159.201 85.199 19.671 1.00 52.83 ? 31 ASP A OD1 1 ATOM 65 O OD2 . ASP A 1 33 ? 159.893 86.807 18.323 1.00 52.54 ? 31 ASP A OD2 1 ATOM 66 N N . LEU A 1 34 ? 164.097 83.758 19.213 1.00 32.65 ? 32 LEU A N 1 ATOM 67 C CA . LEU A 1 34 ? 165.427 83.199 18.943 1.00 30.73 ? 32 LEU A CA 1 ATOM 68 C C . LEU A 1 34 ? 166.197 83.419 20.195 1.00 33.87 ? 32 LEU A C 1 ATOM 69 O O . LEU A 1 34 ? 166.163 84.517 20.725 1.00 33.86 ? 32 LEU A O 1 ATOM 70 C CB . LEU A 1 34 ? 166.134 83.926 17.786 1.00 30.08 ? 32 LEU A CB 1 ATOM 71 C CG . LEU A 1 34 ? 165.555 83.777 16.398 1.00 33.45 ? 32 LEU A CG 1 ATOM 72 C CD1 . LEU A 1 34 ? 166.343 84.584 15.435 1.00 34.07 ? 32 LEU A CD1 1 ATOM 73 C CD2 . LEU A 1 34 ? 165.557 82.339 15.932 1.00 33.63 ? 32 LEU A CD2 1 ATOM 74 N N . VAL A 1 35 ? 166.860 82.390 20.702 1.00 32.17 ? 33 VAL A N 1 ATOM 75 C CA . VAL A 1 35 ? 167.623 82.459 21.954 1.00 32.41 ? 33 VAL A CA 1 ATOM 76 C C . VAL A 1 35 ? 169.140 82.418 21.714 1.00 37.45 ? 33 VAL A C 1 ATOM 77 O O . VAL A 1 35 ? 169.675 81.484 21.123 1.00 38.50 ? 33 VAL A O 1 ATOM 78 C CB . VAL A 1 35 ? 167.142 81.378 22.951 1.00 36.19 ? 33 VAL A CB 1 ATOM 79 C CG1 . VAL A 1 35 ? 168.007 81.327 24.213 1.00 35.97 ? 33 VAL A CG1 1 ATOM 80 C CG2 . VAL A 1 35 ? 165.689 81.616 23.317 1.00 36.20 ? 33 VAL A CG2 1 ATOM 81 N N . LEU A 1 36 ? 169.816 83.442 22.163 1.00 34.47 ? 34 LEU A N 1 ATOM 82 C CA . LEU A 1 36 ? 171.259 83.497 22.057 1.00 34.52 ? 34 LEU A CA 1 ATOM 83 C C . LEU A 1 36 ? 171.922 82.956 23.317 1.00 37.05 ? 34 LEU A C 1 ATOM 84 O O . LEU A 1 36 ? 171.563 83.361 24.429 1.00 36.62 ? 34 LEU A O 1 ATOM 85 C CB . LEU A 1 36 ? 171.735 84.943 21.810 1.00 34.46 ? 34 LEU A CB 1 ATOM 86 C CG . LEU A 1 36 ? 171.457 85.562 20.456 1.00 38.44 ? 34 LEU A CG 1 ATOM 87 C CD1 . LEU A 1 36 ? 172.394 86.768 20.219 1.00 38.42 ? 34 LEU A CD1 1 ATOM 88 C CD2 . LEU A 1 36 ? 171.596 84.554 19.332 1.00 39.76 ? 34 LEU A CD2 1 ATOM 89 N N . GLY A 1 37 ? 172.898 82.073 23.125 1.00 32.26 ? 35 GLY A N 1 ATOM 90 C CA . GLY A 1 37 ? 173.713 81.516 24.204 1.00 30.67 ? 35 GLY A CA 1 ATOM 91 C C . GLY A 1 37 ? 174.775 82.531 24.580 1.00 29.63 ? 35 GLY A C 1 ATOM 92 O O . GLY A 1 37 ? 175.116 83.398 23.782 1.00 27.65 ? 35 GLY A O 1 ATOM 93 N N . GLY A 1 38 ? 175.273 82.440 25.791 1.00 25.53 ? 36 GLY A N 1 ATOM 94 C CA . GLY A 1 38 ? 176.280 83.350 26.319 1.00 24.58 ? 36 GLY A CA 1 ATOM 95 C C . GLY A 1 38 ? 177.201 82.630 27.275 1.00 27.06 ? 36 GLY A C 1 ATOM 96 O O . GLY A 1 38 ? 176.764 81.738 28.013 1.00 26.55 ? 36 GLY A O 1 ATOM 97 N N . LEU A 1 39 ? 178.486 82.989 27.245 1.00 22.91 ? 37 LEU A N 1 ATOM 98 C CA . LEU A 1 39 ? 179.497 82.383 28.101 1.00 22.98 ? 37 LEU A CA 1 ATOM 99 C C . LEU A 1 39 ? 180.456 83.427 28.582 1.00 25.25 ? 37 LEU A C 1 ATOM 100 O O . LEU A 1 39 ? 181.067 84.152 27.773 1.00 23.14 ? 37 LEU A O 1 ATOM 101 C CB . LEU A 1 39 ? 180.239 81.296 27.339 1.00 23.96 ? 37 LEU A CB 1 ATOM 102 C CG . LEU A 1 39 ? 180.878 80.200 28.162 1.00 29.10 ? 37 LEU A CG 1 ATOM 103 C CD1 . LEU A 1 39 ? 179.921 79.654 29.214 1.00 28.75 ? 37 LEU A CD1 1 ATOM 104 C CD2 . LEU A 1 39 ? 181.330 79.097 27.242 1.00 31.14 ? 37 LEU A CD2 1 ATOM 105 N N . PHE A 1 40 ? 180.533 83.542 29.920 1.00 20.81 ? 38 PHE A N 1 ATOM 106 C CA . PHE A 1 40 ? 181.308 84.557 30.616 1.00 19.73 ? 38 PHE A CA 1 ATOM 107 C C . PHE A 1 40 ? 182.039 83.984 31.808 1.00 23.51 ? 38 PHE A C 1 ATOM 108 O O . PHE A 1 40 ? 181.511 83.085 32.459 1.00 22.90 ? 38 PHE A O 1 ATOM 109 C CB . PHE A 1 40 ? 180.375 85.704 31.053 1.00 21.19 ? 38 PHE A CB 1 ATOM 110 C CG . PHE A 1 40 ? 179.792 86.447 29.866 1.00 22.38 ? 38 PHE A CG 1 ATOM 111 C CD1 . PHE A 1 40 ? 180.481 87.502 29.278 1.00 24.77 ? 38 PHE A CD1 1 ATOM 112 C CD2 . PHE A 1 40 ? 178.578 86.071 29.320 1.00 24.53 ? 38 PHE A CD2 1 ATOM 113 C CE1 . PHE A 1 40 ? 179.975 88.152 28.158 1.00 25.69 ? 38 PHE A CE1 1 ATOM 114 C CE2 . PHE A 1 40 ? 178.083 86.710 28.185 1.00 28.36 ? 38 PHE A CE2 1 ATOM 115 C CZ . PHE A 1 40 ? 178.788 87.748 27.607 1.00 25.90 ? 38 PHE A CZ 1 ATOM 116 N N . PRO A 1 41 ? 183.272 84.445 32.113 1.00 19.77 ? 39 PRO A N 1 ATOM 117 C CA . PRO A 1 41 ? 183.953 83.933 33.318 1.00 19.43 ? 39 PRO A CA 1 ATOM 118 C C . PRO A 1 41 ? 183.400 84.702 34.517 1.00 26.32 ? 39 PRO A C 1 ATOM 119 O O . PRO A 1 41 ? 184.126 85.469 35.139 1.00 28.39 ? 39 PRO A O 1 ATOM 120 C CB . PRO A 1 41 ? 185.430 84.242 33.058 1.00 19.84 ? 39 PRO A CB 1 ATOM 121 C CG . PRO A 1 41 ? 185.429 85.372 32.062 1.00 23.06 ? 39 PRO A CG 1 ATOM 122 C CD . PRO A 1 41 ? 184.058 85.509 31.452 1.00 19.07 ? 39 PRO A CD 1 ATOM 123 N N . VAL A 1 42 ? 182.089 84.567 34.782 1.00 23.32 ? 40 VAL A N 1 ATOM 124 C CA . VAL A 1 42 ? 181.413 85.294 35.867 1.00 24.01 ? 40 VAL A CA 1 ATOM 125 C C . VAL A 1 42 ? 182.207 85.088 37.169 1.00 30.98 ? 40 VAL A C 1 ATOM 126 O O . VAL A 1 42 ? 182.504 86.050 37.873 1.00 29.31 ? 40 VAL A O 1 ATOM 127 C CB . VAL A 1 42 ? 179.903 84.939 36.003 1.00 26.18 ? 40 VAL A CB 1 ATOM 128 C CG1 . VAL A 1 42 ? 179.239 85.822 37.051 1.00 26.76 ? 40 VAL A CG1 1 ATOM 129 C CG2 . VAL A 1 42 ? 179.164 85.035 34.675 1.00 24.29 ? 40 VAL A CG2 1 ATOM 130 N N . HIS A 1 43 ? 182.666 83.844 37.394 1.00 31.68 ? 41 HIS A N 1 ATOM 131 C CA . HIS A 1 43 ? 183.528 83.493 38.523 1.00 32.34 ? 41 HIS A CA 1 ATOM 132 C C . HIS A 1 43 ? 184.934 83.150 38.104 1.00 35.31 ? 41 HIS A C 1 ATOM 133 O O . HIS A 1 43 ? 185.175 82.758 36.962 1.00 34.19 ? 41 HIS A O 1 ATOM 134 C CB . HIS A 1 43 ? 182.934 82.341 39.319 1.00 33.22 ? 41 HIS A CB 1 ATOM 135 C CG . HIS A 1 43 ? 181.795 82.793 40.168 1.00 37.13 ? 41 HIS A CG 1 ATOM 136 N ND1 . HIS A 1 43 ? 180.486 82.664 39.746 1.00 38.91 ? 41 HIS A ND1 1 ATOM 137 C CD2 . HIS A 1 43 ? 181.810 83.420 41.364 1.00 39.01 ? 41 HIS A CD2 1 ATOM 138 C CE1 . HIS A 1 43 ? 179.745 83.167 40.712 1.00 38.37 ? 41 HIS A CE1 1 ATOM 139 N NE2 . HIS A 1 43 ? 180.500 83.628 41.708 1.00 38.93 ? 41 HIS A NE2 1 ATOM 140 N N . GLN A 1 44 ? 185.864 83.320 39.035 1.00 32.75 ? 42 GLN A N 1 ATOM 141 C CA . GLN A 1 44 ? 187.259 82.957 38.872 1.00 33.26 ? 42 GLN A CA 1 ATOM 142 C C . GLN A 1 44 ? 187.359 81.459 39.097 1.00 41.46 ? 42 GLN A C 1 ATOM 143 O O . GLN A 1 44 ? 186.361 80.819 39.478 1.00 40.40 ? 42 GLN A O 1 ATOM 144 C CB . GLN A 1 44 ? 188.124 83.697 39.890 1.00 34.00 ? 42 GLN A CB 1 ATOM 145 C CG . GLN A 1 44 ? 188.292 85.158 39.567 1.00 47.32 ? 42 GLN A CG 1 ATOM 146 C CD . GLN A 1 44 ? 189.138 85.916 40.561 1.00 76.76 ? 42 GLN A CD 1 ATOM 147 O OE1 . GLN A 1 44 ? 189.833 85.349 41.426 1.00 69.73 ? 42 GLN A OE1 1 ATOM 148 N NE2 . GLN A 1 44 ? 189.121 87.237 40.422 1.00 78.88 ? 42 GLN A NE2 1 ATOM 149 N N . LYS A 1 45 ? 188.550 80.891 38.838 1.00 42.03 ? 43 LYS A N 1 ATOM 150 C CA . LYS A 1 45 ? 188.804 79.465 39.032 1.00 43.89 ? 43 LYS A CA 1 ATOM 151 C C . LYS A 1 45 ? 188.631 79.108 40.520 1.00 52.67 ? 43 LYS A C 1 ATOM 152 O O . LYS A 1 45 ? 189.004 79.891 41.400 1.00 51.50 ? 43 LYS A O 1 ATOM 153 C CB . LYS A 1 45 ? 190.215 79.100 38.542 1.00 46.41 ? 43 LYS A CB 1 ATOM 154 C CG . LYS A 1 45 ? 190.258 77.875 37.648 1.00 57.76 ? 43 LYS A CG 1 ATOM 155 C CD . LYS A 1 45 ? 191.587 77.785 36.892 1.00 69.78 ? 43 LYS A CD 1 ATOM 156 C CE . LYS A 1 45 ? 191.675 76.586 35.958 1.00 80.09 ? 43 LYS A CE 1 ATOM 157 N NZ . LYS A 1 45 ? 192.210 75.366 36.641 1.00 85.56 ? 43 LYS A NZ 1 ATOM 158 N N . GLY A 1 46 ? 188.007 77.961 40.772 1.00 53.60 ? 44 GLY A N 1 ATOM 159 C CA . GLY A 1 46 ? 187.774 77.450 42.116 1.00 54.89 ? 44 GLY A CA 1 ATOM 160 C C . GLY A 1 46 ? 189.048 76.976 42.779 1.00 63.45 ? 44 GLY A C 1 ATOM 161 O O . GLY A 1 46 ? 190.120 76.986 42.160 1.00 62.30 ? 44 GLY A O 1 ATOM 162 N N . GLY A 1 47 ? 188.920 76.543 44.032 1.00 64.54 ? 45 GLY A N 1 ATOM 163 C CA . GLY A 1 47 ? 190.041 76.060 44.835 1.00 66.32 ? 45 GLY A CA 1 ATOM 164 C C . GLY A 1 47 ? 190.602 74.717 44.398 1.00 73.73 ? 45 GLY A C 1 ATOM 165 O O . GLY A 1 47 ? 190.531 74.363 43.217 1.00 73.03 ? 45 GLY A O 1 ATOM 166 N N . PRO A 1 48 ? 191.174 73.921 45.330 1.00 73.08 ? 46 PRO A N 1 ATOM 167 C CA . PRO A 1 48 ? 191.693 72.600 44.926 1.00 73.13 ? 46 PRO A CA 1 ATOM 168 C C . PRO A 1 48 ? 190.577 71.586 44.661 1.00 76.45 ? 46 PRO A C 1 ATOM 169 O O . PRO A 1 48 ? 190.802 70.630 43.917 1.00 75.68 ? 46 PRO A O 1 ATOM 170 C CB . PRO A 1 48 ? 192.598 72.180 46.098 1.00 74.92 ? 46 PRO A CB 1 ATOM 171 C CG . PRO A 1 48 ? 192.507 73.284 47.131 1.00 79.25 ? 46 PRO A CG 1 ATOM 172 C CD . PRO A 1 48 ? 191.329 74.140 46.783 1.00 74.95 ? 46 PRO A CD 1 ATOM 173 N N . ALA A 1 49 ? 189.371 71.806 45.249 1.00 72.76 ? 47 ALA A N 1 ATOM 174 C CA . ALA A 1 49 ? 188.203 70.926 45.087 1.00 72.42 ? 47 ALA A CA 1 ATOM 175 C C . ALA A 1 49 ? 186.991 71.629 44.468 1.00 74.28 ? 47 ALA A C 1 ATOM 176 O O . ALA A 1 49 ? 186.247 70.991 43.710 1.00 74.40 ? 47 ALA A O 1 ATOM 177 C CB . ALA A 1 49 ? 187.817 70.301 46.419 1.00 73.28 ? 47 ALA A CB 1 ATOM 178 N N . GLU A 1 50 ? 186.777 72.927 44.820 1.00 67.70 ? 48 GLU A N 1 ATOM 179 C CA . GLU A 1 50 ? 185.680 73.773 44.324 1.00 65.01 ? 48 GLU A CA 1 ATOM 180 C C . GLU A 1 50 ? 185.878 74.054 42.828 1.00 63.86 ? 48 GLU A C 1 ATOM 181 O O . GLU A 1 50 ? 187.015 74.253 42.400 1.00 63.91 ? 48 GLU A O 1 ATOM 182 C CB . GLU A 1 50 ? 185.612 75.085 45.128 1.00 66.02 ? 48 GLU A CB 1 ATOM 183 N N . ASP A 1 51 ? 184.796 74.016 42.031 1.00 56.48 ? 49 ASP A N 1 ATOM 184 C CA . ASP A 1 51 ? 184.889 74.257 40.588 1.00 55.15 ? 49 ASP A CA 1 ATOM 185 C C . ASP A 1 51 ? 184.899 75.755 40.273 1.00 53.07 ? 49 ASP A C 1 ATOM 186 O O . ASP A 1 51 ? 185.575 76.176 39.332 1.00 51.99 ? 49 ASP A O 1 ATOM 187 C CB . ASP A 1 51 ? 183.779 73.503 39.805 1.00 57.85 ? 49 ASP A CB 1 ATOM 188 C CG . ASP A 1 51 ? 184.206 72.882 38.467 1.00 71.80 ? 49 ASP A CG 1 ATOM 189 O OD1 . ASP A 1 51 ? 185.428 72.712 38.247 1.00 72.81 ? 49 ASP A OD1 1 ATOM 190 O OD2 . ASP A 1 51 ? 183.311 72.484 37.679 1.00 78.16 ? 49 ASP A OD2 1 ATOM 191 N N . CYS A 1 52 ? 184.195 76.552 41.100 1.00 46.19 ? 50 CYS A N 1 ATOM 192 C CA . CYS A 1 52 ? 184.083 78.003 40.971 1.00 44.87 ? 50 CYS A CA 1 ATOM 193 C C . CYS A 1 52 ? 184.616 78.757 42.181 1.00 46.42 ? 50 CYS A C 1 ATOM 194 O O . CYS A 1 52 ? 184.378 78.366 43.324 1.00 46.36 ? 50 CYS A O 1 ATOM 195 C CB . CYS A 1 52 ? 182.644 78.398 40.658 1.00 45.37 ? 50 CYS A CB 1 ATOM 196 S SG . CYS A 1 52 ? 181.920 77.479 39.264 1.00 49.38 ? 50 CYS A SG 1 ATOM 197 N N . GLY A 1 53 ? 185.335 79.838 41.904 1.00 40.62 ? 51 GLY A N 1 ATOM 198 C CA . GLY A 1 53 ? 185.938 80.706 42.907 1.00 38.31 ? 51 GLY A CA 1 ATOM 199 C C . GLY A 1 53 ? 185.176 81.995 43.115 1.00 38.65 ? 51 GLY A C 1 ATOM 200 O O . GLY A 1 53 ? 183.944 81.992 43.049 1.00 38.60 ? 51 GLY A O 1 ATOM 201 N N . PRO A 1 54 ? 185.876 83.119 43.396 1.00 33.73 ? 52 PRO A N 1 ATOM 202 C CA . PRO A 1 54 ? 185.153 84.388 43.642 1.00 33.58 ? 52 PRO A CA 1 ATOM 203 C C . PRO A 1 54 ? 184.697 85.097 42.375 1.00 39.53 ? 52 PRO A C 1 ATOM 204 O O . PRO A 1 54 ? 185.220 84.821 41.296 1.00 40.36 ? 52 PRO A O 1 ATOM 205 C CB . PRO A 1 54 ? 186.160 85.240 44.427 1.00 34.50 ? 52 PRO A CB 1 ATOM 206 C CG . PRO A 1 54 ? 187.501 84.615 44.184 1.00 38.32 ? 52 PRO A CG 1 ATOM 207 C CD . PRO A 1 54 ? 187.341 83.284 43.524 1.00 34.23 ? 52 PRO A CD 1 ATOM 208 N N . VAL A 1 55 ? 183.764 86.047 42.518 1.00 36.23 ? 53 VAL A N 1 ATOM 209 C CA . VAL A 1 55 ? 183.210 86.832 41.422 1.00 36.43 ? 53 VAL A CA 1 ATOM 210 C C . VAL A 1 55 ? 184.301 87.647 40.688 1.00 40.63 ? 53 VAL A C 1 ATOM 211 O O . VAL A 1 55 ? 185.198 88.209 41.319 1.00 40.79 ? 53 VAL A O 1 ATOM 212 C CB . VAL A 1 55 ? 182.006 87.697 41.907 1.00 40.65 ? 53 VAL A CB 1 ATOM 213 C CG1 . VAL A 1 55 ? 181.824 88.976 41.083 1.00 40.97 ? 53 VAL A CG1 1 ATOM 214 C CG2 . VAL A 1 55 ? 180.716 86.890 41.898 1.00 40.23 ? 53 VAL A CG2 1 ATOM 215 N N . ASN A 1 56 ? 184.230 87.657 39.353 1.00 35.89 ? 54 ASN A N 1 ATOM 216 C CA . ASN A 1 56 ? 185.118 88.424 38.509 1.00 35.55 ? 54 ASN A CA 1 ATOM 217 C C . ASN A 1 56 ? 184.341 89.691 38.173 1.00 39.82 ? 54 ASN A C 1 ATOM 218 O O . ASN A 1 56 ? 183.423 89.665 37.356 1.00 39.23 ? 54 ASN A O 1 ATOM 219 C CB . ASN A 1 56 ? 185.452 87.626 37.248 1.00 37.97 ? 54 ASN A CB 1 ATOM 220 C CG . ASN A 1 56 ? 186.865 87.746 36.783 1.00 70.08 ? 54 ASN A CG 1 ATOM 221 O OD1 . ASN A 1 56 ? 187.821 87.840 37.572 1.00 63.23 ? 54 ASN A OD1 1 ATOM 222 N ND2 . ASN A 1 56 ? 187.026 87.708 35.476 1.00 68.79 ? 54 ASN A ND2 1 ATOM 223 N N . GLU A 1 57 ? 184.636 90.780 38.874 1.00 37.76 ? 55 GLU A N 1 ATOM 224 C CA . GLU A 1 57 ? 183.930 92.046 38.670 1.00 38.18 ? 55 GLU A CA 1 ATOM 225 C C . GLU A 1 57 ? 183.996 92.572 37.212 1.00 39.26 ? 55 GLU A C 1 ATOM 226 O O . GLU A 1 57 ? 182.949 92.834 36.633 1.00 37.43 ? 55 GLU A O 1 ATOM 227 C CB . GLU A 1 57 ? 184.429 93.103 39.685 1.00 40.00 ? 55 GLU A CB 1 ATOM 228 C CG . GLU A 1 57 ? 184.100 94.564 39.375 1.00 53.48 ? 55 GLU A CG 1 ATOM 229 C CD . GLU A 1 57 ? 184.291 95.519 40.543 1.00 87.07 ? 55 GLU A CD 1 ATOM 230 O OE1 . GLU A 1 57 ? 184.675 96.687 40.299 1.00 81.43 ? 55 GLU A OE1 1 ATOM 231 O OE2 . GLU A 1 57 ? 184.047 95.106 41.701 1.00 89.65 ? 55 GLU A OE2 1 ATOM 232 N N . HIS A 1 58 ? 185.212 92.723 36.638 1.00 35.42 ? 56 HIS A N 1 ATOM 233 C CA . HIS A 1 58 ? 185.402 93.333 35.324 1.00 35.08 ? 56 HIS A CA 1 ATOM 234 C C . HIS A 1 58 ? 185.174 92.429 34.162 1.00 36.97 ? 56 HIS A C 1 ATOM 235 O O . HIS A 1 58 ? 184.319 92.728 33.316 1.00 36.73 ? 56 HIS A O 1 ATOM 236 C CB . HIS A 1 58 ? 186.780 93.986 35.214 1.00 36.68 ? 56 HIS A CB 1 ATOM 237 C CG . HIS A 1 58 ? 186.839 95.306 35.904 1.00 41.14 ? 56 HIS A CG 1 ATOM 238 N ND1 . HIS A 1 58 ? 186.764 95.401 37.294 1.00 43.53 ? 56 HIS A ND1 1 ATOM 239 C CD2 . HIS A 1 58 ? 186.896 96.553 35.377 1.00 44.25 ? 56 HIS A CD2 1 ATOM 240 C CE1 . HIS A 1 58 ? 186.785 96.698 37.566 1.00 43.99 ? 56 HIS A CE1 1 ATOM 241 N NE2 . HIS A 1 58 ? 186.859 97.435 36.445 1.00 44.69 ? 56 HIS A NE2 1 ATOM 242 N N . ARG A 1 59 ? 185.929 91.329 34.091 1.00 30.62 ? 57 ARG A N 1 ATOM 243 C CA . ARG A 1 59 ? 185.807 90.459 32.939 1.00 28.96 ? 57 ARG A CA 1 ATOM 244 C C . ARG A 1 59 ? 184.639 89.458 33.051 1.00 34.42 ? 57 ARG A C 1 ATOM 245 O O . ARG A 1 59 ? 184.373 88.732 32.092 1.00 35.40 ? 57 ARG A O 1 ATOM 246 C CB . ARG A 1 59 ? 187.145 89.795 32.648 1.00 23.83 ? 57 ARG A CB 1 ATOM 247 C CG . ARG A 1 59 ? 188.186 90.791 32.163 1.00 17.92 ? 57 ARG A CG 1 ATOM 248 C CD . ARG A 1 59 ? 189.505 90.106 31.893 1.00 14.64 ? 57 ARG A CD 1 ATOM 249 N NE . ARG A 1 59 ? 190.467 90.959 31.198 1.00 15.16 ? 57 ARG A NE 1 ATOM 250 C CZ . ARG A 1 59 ? 191.681 90.569 30.844 1.00 27.91 ? 57 ARG A CZ 1 ATOM 251 N NH1 . ARG A 1 59 ? 192.105 89.349 31.144 1.00 26.68 ? 57 ARG A NH1 1 ATOM 252 N NH2 . ARG A 1 59 ? 192.504 91.412 30.231 1.00 17.36 ? 57 ARG A NH2 1 ATOM 253 N N . GLY A 1 60 ? 183.908 89.491 34.167 1.00 29.86 ? 58 GLY A N 1 ATOM 254 C CA . GLY A 1 60 ? 182.740 88.649 34.380 1.00 28.99 ? 58 GLY A CA 1 ATOM 255 C C . GLY A 1 60 ? 181.467 89.475 34.302 1.00 32.28 ? 58 GLY A C 1 ATOM 256 O O . GLY A 1 60 ? 180.790 89.542 33.261 1.00 31.25 ? 58 GLY A O 1 ATOM 257 N N . ILE A 1 61 ? 181.173 90.152 35.402 1.00 29.14 ? 59 ILE A N 1 ATOM 258 C CA . ILE A 1 61 ? 179.964 90.956 35.615 1.00 28.99 ? 59 ILE A CA 1 ATOM 259 C C . ILE A 1 61 ? 179.754 92.024 34.552 1.00 31.47 ? 59 ILE A C 1 ATOM 260 O O . ILE A 1 61 ? 178.701 92.016 33.893 1.00 31.53 ? 59 ILE A O 1 ATOM 261 C CB . ILE A 1 61 ? 179.948 91.535 37.055 1.00 31.84 ? 59 ILE A CB 1 ATOM 262 C CG1 . ILE A 1 61 ? 179.857 90.403 38.117 1.00 30.33 ? 59 ILE A CG1 1 ATOM 263 C CG2 . ILE A 1 61 ? 178.865 92.611 37.232 1.00 34.43 ? 59 ILE A CG2 1 ATOM 264 C CD1 . ILE A 1 61 ? 178.720 89.403 37.905 1.00 31.67 ? 59 ILE A CD1 1 ATOM 265 N N . GLN A 1 62 ? 180.735 92.922 34.379 1.00 26.25 ? 60 GLN A N 1 ATOM 266 C CA . GLN A 1 62 ? 180.640 93.974 33.371 1.00 26.47 ? 60 GLN A CA 1 ATOM 267 C C . GLN A 1 62 ? 180.444 93.399 31.958 1.00 33.01 ? 60 GLN A C 1 ATOM 268 O O . GLN A 1 62 ? 179.554 93.840 31.227 1.00 32.99 ? 60 GLN A O 1 ATOM 269 C CB . GLN A 1 62 ? 181.854 94.883 33.438 1.00 27.14 ? 60 GLN A CB 1 ATOM 270 C CG . GLN A 1 62 ? 181.511 96.263 33.899 1.00 28.84 ? 60 GLN A CG 1 ATOM 271 C CD . GLN A 1 62 ? 182.645 97.183 33.604 1.00 48.16 ? 60 GLN A CD 1 ATOM 272 O OE1 . GLN A 1 62 ? 182.859 97.598 32.456 1.00 40.98 ? 60 GLN A OE1 1 ATOM 273 N NE2 . GLN A 1 62 ? 183.424 97.475 34.628 1.00 43.98 ? 60 GLN A NE2 1 ATOM 274 N N . ARG A 1 63 ? 181.225 92.364 31.605 1.00 30.10 ? 61 ARG A N 1 ATOM 275 C CA . ARG A 1 63 ? 181.119 91.733 30.296 1.00 29.58 ? 61 ARG A CA 1 ATOM 276 C C . ARG A 1 63 ? 179.770 91.101 30.071 1.00 33.02 ? 61 ARG A C 1 ATOM 277 O O . ARG A 1 63 ? 179.214 91.294 29.001 1.00 32.46 ? 61 ARG A O 1 ATOM 278 C CB . ARG A 1 63 ? 182.257 90.745 30.054 1.00 27.95 ? 61 ARG A CB 1 ATOM 279 C CG . ARG A 1 63 ? 183.499 91.409 29.502 1.00 28.42 ? 61 ARG A CG 1 ATOM 280 C CD . ARG A 1 63 ? 184.549 90.365 29.172 1.00 31.75 ? 61 ARG A CD 1 ATOM 281 N NE . ARG A 1 63 ? 185.870 90.958 29.004 1.00 21.53 ? 61 ARG A NE 1 ATOM 282 C CZ . ARG A 1 63 ? 186.984 90.271 28.802 1.00 35.80 ? 61 ARG A CZ 1 ATOM 283 N NH1 . ARG A 1 63 ? 186.955 88.943 28.751 1.00 23.82 ? 61 ARG A NH1 1 ATOM 284 N NH2 . ARG A 1 63 ? 188.137 90.902 28.664 1.00 27.24 ? 61 ARG A NH2 1 ATOM 285 N N . LEU A 1 64 ? 179.235 90.356 31.066 1.00 30.48 ? 62 LEU A N 1 ATOM 286 C CA . LEU A 1 64 ? 177.912 89.725 30.955 1.00 30.87 ? 62 LEU A CA 1 ATOM 287 C C . LEU A 1 64 ? 176.815 90.809 30.804 1.00 33.24 ? 62 LEU A C 1 ATOM 288 O O . LEU A 1 64 ? 176.032 90.739 29.863 1.00 32.69 ? 62 LEU A O 1 ATOM 289 C CB . LEU A 1 64 ? 177.661 88.787 32.153 1.00 31.46 ? 62 LEU A CB 1 ATOM 290 C CG . LEU A 1 64 ? 176.266 88.749 32.793 1.00 36.90 ? 62 LEU A CG 1 ATOM 291 C CD1 . LEU A 1 64 ? 175.332 87.913 31.994 1.00 37.15 ? 62 LEU A CD1 1 ATOM 292 C CD2 . LEU A 1 64 ? 176.337 88.175 34.189 1.00 39.43 ? 62 LEU A CD2 1 ATOM 293 N N . GLU A 1 65 ? 176.838 91.841 31.684 1.00 27.86 ? 63 GLU A N 1 ATOM 294 C CA . GLU A 1 65 ? 175.910 92.970 31.687 1.00 26.62 ? 63 GLU A CA 1 ATOM 295 C C . GLU A 1 65 ? 175.865 93.652 30.373 1.00 30.68 ? 63 GLU A C 1 ATOM 296 O O . GLU A 1 65 ? 174.769 93.992 29.922 1.00 31.83 ? 63 GLU A O 1 ATOM 297 C CB . GLU A 1 65 ? 176.197 93.984 32.823 1.00 27.22 ? 63 GLU A CB 1 ATOM 298 C CG . GLU A 1 65 ? 175.674 93.560 34.190 1.00 24.60 ? 63 GLU A CG 1 ATOM 299 C CD . GLU A 1 65 ? 174.217 93.127 34.348 1.00 43.74 ? 63 GLU A CD 1 ATOM 300 O OE1 . GLU A 1 65 ? 173.359 93.474 33.503 1.00 35.11 ? 63 GLU A OE1 1 ATOM 301 O OE2 . GLU A 1 65 ? 173.933 92.435 35.349 1.00 45.66 ? 63 GLU A OE2 1 ATOM 302 N N . ALA A 1 66 ? 177.044 93.786 29.717 1.00 26.12 ? 64 ALA A N 1 ATOM 303 C CA . ALA A 1 66 ? 177.207 94.347 28.366 1.00 24.63 ? 64 ALA A CA 1 ATOM 304 C C . ALA A 1 66 ? 176.423 93.524 27.324 1.00 26.77 ? 64 ALA A C 1 ATOM 305 O O . ALA A 1 66 ? 175.844 94.119 26.418 1.00 25.50 ? 64 ALA A O 1 ATOM 306 C CB . ALA A 1 66 ? 178.676 94.426 27.999 1.00 25.20 ? 64 ALA A CB 1 ATOM 307 N N . MET A 1 67 ? 176.330 92.174 27.488 1.00 23.63 ? 65 MET A N 1 ATOM 308 C CA . MET A 1 67 ? 175.510 91.371 26.576 1.00 23.45 ? 65 MET A CA 1 ATOM 309 C C . MET A 1 67 ? 174.028 91.699 26.814 1.00 29.99 ? 65 MET A C 1 ATOM 310 O O . MET A 1 67 ? 173.266 91.826 25.853 1.00 29.66 ? 65 MET A O 1 ATOM 311 C CB . MET A 1 67 ? 175.761 89.861 26.725 1.00 24.98 ? 65 MET A CB 1 ATOM 312 C CG . MET A 1 67 ? 174.934 89.045 25.755 1.00 27.16 ? 65 MET A CG 1 ATOM 313 S SD . MET A 1 67 ? 175.443 87.342 25.685 1.00 30.14 ? 65 MET A SD 1 ATOM 314 C CE . MET A 1 67 ? 174.066 86.602 24.777 1.00 26.30 ? 65 MET A CE 1 ATOM 315 N N . LEU A 1 68 ? 173.638 91.868 28.094 1.00 28.36 ? 66 LEU A N 1 ATOM 316 C CA . LEU A 1 68 ? 172.265 92.224 28.487 1.00 27.97 ? 66 LEU A CA 1 ATOM 317 C C . LEU A 1 68 ? 171.856 93.607 27.961 1.00 31.80 ? 66 LEU A C 1 ATOM 318 O O . LEU A 1 68 ? 170.790 93.747 27.380 1.00 29.10 ? 66 LEU A O 1 ATOM 319 C CB . LEU A 1 68 ? 172.083 92.100 30.003 1.00 27.20 ? 66 LEU A CB 1 ATOM 320 C CG . LEU A 1 68 ? 172.278 90.674 30.575 1.00 29.83 ? 66 LEU A CG 1 ATOM 321 C CD1 . LEU A 1 68 ? 171.995 90.630 32.105 1.00 28.93 ? 66 LEU A CD1 1 ATOM 322 C CD2 . LEU A 1 68 ? 171.421 89.663 29.850 1.00 28.60 ? 66 LEU A CD2 1 ATOM 323 N N . PHE A 1 69 ? 172.755 94.584 28.076 1.00 31.37 ? 67 PHE A N 1 ATOM 324 C CA . PHE A 1 69 ? 172.591 95.947 27.570 1.00 32.32 ? 67 PHE A CA 1 ATOM 325 C C . PHE A 1 69 ? 172.326 95.899 26.053 1.00 38.58 ? 67 PHE A C 1 ATOM 326 O O . PHE A 1 69 ? 171.305 96.406 25.587 1.00 39.26 ? 67 PHE A O 1 ATOM 327 C CB . PHE A 1 69 ? 173.862 96.745 27.909 1.00 34.22 ? 67 PHE A CB 1 ATOM 328 C CG . PHE A 1 69 ? 174.092 98.019 27.140 1.00 36.50 ? 67 PHE A CG 1 ATOM 329 C CD1 . PHE A 1 69 ? 173.496 99.210 27.541 1.00 39.57 ? 67 PHE A CD1 1 ATOM 330 C CD2 . PHE A 1 69 ? 174.946 98.045 26.042 1.00 39.25 ? 67 PHE A CD2 1 ATOM 331 C CE1 . PHE A 1 69 ? 173.724 100.394 26.837 1.00 40.52 ? 67 PHE A CE1 1 ATOM 332 C CE2 . PHE A 1 69 ? 175.188 99.239 25.352 1.00 42.02 ? 67 PHE A CE2 1 ATOM 333 C CZ . PHE A 1 69 ? 174.575 100.403 25.756 1.00 39.76 ? 67 PHE A CZ 1 ATOM 334 N N . ALA A 1 70 ? 173.235 95.246 25.298 1.00 35.52 ? 68 ALA A N 1 ATOM 335 C CA . ALA A 1 70 ? 173.165 95.061 23.852 1.00 34.01 ? 68 ALA A CA 1 ATOM 336 C C . ALA A 1 70 ? 171.842 94.423 23.442 1.00 35.91 ? 68 ALA A C 1 ATOM 337 O O . ALA A 1 70 ? 171.163 94.964 22.583 1.00 35.96 ? 68 ALA A O 1 ATOM 338 C CB . ALA A 1 70 ? 174.339 94.218 23.381 1.00 34.52 ? 68 ALA A CB 1 ATOM 339 N N . LEU A 1 71 ? 171.444 93.316 24.094 1.00 32.45 ? 69 LEU A N 1 ATOM 340 C CA . LEU A 1 71 ? 170.170 92.624 23.831 1.00 31.30 ? 69 LEU A CA 1 ATOM 341 C C . LEU A 1 71 ? 168.987 93.564 24.041 1.00 37.29 ? 69 LEU A C 1 ATOM 342 O O . LEU A 1 71 ? 168.180 93.753 23.120 1.00 37.02 ? 69 LEU A O 1 ATOM 343 C CB . LEU A 1 71 ? 170.029 91.375 24.694 1.00 30.10 ? 69 LEU A CB 1 ATOM 344 C CG . LEU A 1 71 ? 170.797 90.123 24.260 1.00 31.96 ? 69 LEU A CG 1 ATOM 345 C CD1 . LEU A 1 71 ? 170.684 89.044 25.321 1.00 30.26 ? 69 LEU A CD1 1 ATOM 346 C CD2 . LEU A 1 71 ? 170.356 89.616 22.879 1.00 28.98 ? 69 LEU A CD2 1 ATOM 347 N N . ASP A 1 72 ? 168.961 94.252 25.204 1.00 35.10 ? 70 ASP A N 1 ATOM 348 C CA . ASP A 1 72 ? 167.940 95.262 25.522 1.00 35.00 ? 70 ASP A CA 1 ATOM 349 C C . ASP A 1 72 ? 167.788 96.267 24.369 1.00 39.55 ? 70 ASP A C 1 ATOM 350 O O . ASP A 1 72 ? 166.664 96.471 23.900 1.00 40.00 ? 70 ASP A O 1 ATOM 351 C CB . ASP A 1 72 ? 168.238 95.984 26.858 1.00 36.10 ? 70 ASP A CB 1 ATOM 352 C CG . ASP A 1 72 ? 167.973 95.195 28.141 1.00 47.09 ? 70 ASP A CG 1 ATOM 353 O OD1 . ASP A 1 72 ? 167.721 93.957 28.055 1.00 48.73 ? 70 ASP A OD1 1 ATOM 354 O OD2 . ASP A 1 72 ? 168.036 95.804 29.233 1.00 52.29 ? 70 ASP A OD2 1 ATOM 355 N N . ARG A 1 73 ? 168.918 96.811 23.858 1.00 35.00 ? 71 ARG A N 1 ATOM 356 C CA . ARG A 1 73 ? 168.904 97.788 22.769 1.00 34.82 ? 71 ARG A CA 1 ATOM 357 C C . ARG A 1 73 ? 168.458 97.204 21.450 1.00 40.64 ? 71 ARG A C 1 ATOM 358 O O . ARG A 1 73 ? 167.677 97.851 20.751 1.00 41.88 ? 71 ARG A O 1 ATOM 359 C CB . ARG A 1 73 ? 170.242 98.522 22.641 1.00 35.25 ? 71 ARG A CB 1 ATOM 360 C CG . ARG A 1 73 ? 170.601 99.398 23.848 1.00 40.39 ? 71 ARG A CG 1 ATOM 361 C CD . ARG A 1 73 ? 169.621 100.526 24.055 1.00 50.44 ? 71 ARG A CD 1 ATOM 362 N NE . ARG A 1 73 ? 170.160 101.556 24.940 1.00 62.33 ? 71 ARG A NE 1 ATOM 363 C CZ . ARG A 1 73 ? 170.629 102.729 24.521 1.00 69.44 ? 71 ARG A CZ 1 ATOM 364 N NH1 . ARG A 1 73 ? 171.091 103.613 25.393 1.00 49.72 ? 71 ARG A NH1 1 ATOM 365 N NH2 . ARG A 1 73 ? 170.620 103.033 23.225 1.00 48.92 ? 71 ARG A NH2 1 ATOM 366 N N . ILE A 1 74 ? 168.882 95.968 21.123 1.00 37.46 ? 72 ILE A N 1 ATOM 367 C CA . ILE A 1 74 ? 168.438 95.251 19.909 1.00 36.49 ? 72 ILE A CA 1 ATOM 368 C C . ILE A 1 74 ? 166.887 95.004 19.938 1.00 41.63 ? 72 ILE A C 1 ATOM 369 O O . ILE A 1 74 ? 166.234 95.064 18.894 1.00 42.06 ? 72 ILE A O 1 ATOM 370 C CB . ILE A 1 74 ? 169.263 93.935 19.713 1.00 38.21 ? 72 ILE A CB 1 ATOM 371 C CG1 . ILE A 1 74 ? 170.738 94.269 19.405 1.00 38.09 ? 72 ILE A CG1 1 ATOM 372 C CG2 . ILE A 1 74 ? 168.672 93.041 18.600 1.00 36.09 ? 72 ILE A CG2 1 ATOM 373 C CD1 . ILE A 1 74 ? 171.724 93.313 19.907 1.00 42.48 ? 72 ILE A CD1 1 ATOM 374 N N . ASN A 1 75 ? 166.323 94.731 21.129 1.00 38.30 ? 73 ASN A N 1 ATOM 375 C CA . ASN A 1 75 ? 164.893 94.466 21.306 1.00 38.42 ? 73 ASN A CA 1 ATOM 376 C C . ASN A 1 75 ? 164.018 95.740 21.354 1.00 45.55 ? 73 ASN A C 1 ATOM 377 O O . ASN A 1 75 ? 162.791 95.630 21.411 1.00 46.97 ? 73 ASN A O 1 ATOM 378 C CB . ASN A 1 75 ? 164.654 93.579 22.525 1.00 34.05 ? 73 ASN A CB 1 ATOM 379 C CG . ASN A 1 75 ? 165.187 92.181 22.383 1.00 42.89 ? 73 ASN A CG 1 ATOM 380 O OD1 . ASN A 1 75 ? 165.092 91.553 21.322 1.00 28.62 ? 73 ASN A OD1 1 ATOM 381 N ND2 . ASN A 1 75 ? 165.759 91.656 23.465 1.00 37.30 ? 73 ASN A ND2 1 ATOM 382 N N . ARG A 1 76 ? 164.645 96.930 21.315 1.00 41.51 ? 74 ARG A N 1 ATOM 383 C CA . ARG A 1 76 ? 163.996 98.241 21.275 1.00 41.39 ? 74 ARG A CA 1 ATOM 384 C C . ARG A 1 76 ? 164.343 98.868 19.918 1.00 47.64 ? 74 ARG A C 1 ATOM 385 O O . ARG A 1 76 ? 164.071 100.056 19.715 1.00 47.71 ? 74 ARG A O 1 ATOM 386 C CB . ARG A 1 76 ? 164.587 99.152 22.362 1.00 42.98 ? 74 ARG A CB 1 ATOM 387 C CG . ARG A 1 76 ? 163.827 99.212 23.668 1.00 58.86 ? 74 ARG A CG 1 ATOM 388 C CD . ARG A 1 76 ? 164.359 100.361 24.503 1.00 73.58 ? 74 ARG A CD 1 ATOM 389 N NE . ARG A 1 76 ? 165.472 99.963 25.366 1.00 84.72 ? 74 ARG A NE 1 ATOM 390 C CZ . ARG A 1 76 ? 166.349 100.808 25.904 1.00 100.39 ? 74 ARG A CZ 1 ATOM 391 N NH1 . ARG A 1 76 ? 166.273 102.109 25.648 1.00 86.21 ? 74 ARG A NH1 1 ATOM 392 N NH2 . ARG A 1 76 ? 167.319 100.356 26.688 1.00 87.29 ? 74 ARG A NH2 1 ATOM 393 N N . ASP A 1 77 ? 165.008 98.100 19.015 1.00 45.29 ? 75 ASP A N 1 ATOM 394 C CA . ASP A 1 77 ? 165.473 98.614 17.724 1.00 45.40 ? 75 ASP A CA 1 ATOM 395 C C . ASP A 1 77 ? 164.517 98.285 16.567 1.00 51.47 ? 75 ASP A C 1 ATOM 396 O O . ASP A 1 77 ? 164.384 97.123 16.191 1.00 51.75 ? 75 ASP A O 1 ATOM 397 C CB . ASP A 1 77 ? 166.931 98.170 17.420 1.00 46.17 ? 75 ASP A CB 1 ATOM 398 C CG . ASP A 1 77 ? 167.657 98.935 16.308 1.00 48.07 ? 75 ASP A CG 1 ATOM 399 O OD1 . ASP A 1 77 ? 166.989 99.400 15.366 1.00 44.88 ? 75 ASP A OD1 1 ATOM 400 O OD2 . ASP A 1 77 ? 168.903 99.007 16.351 1.00 56.31 ? 75 ASP A OD2 1 ATOM 401 N N . PRO A 1 78 ? 163.906 99.325 15.953 1.00 49.02 ? 76 PRO A N 1 ATOM 402 C CA . PRO A 1 78 ? 162.997 99.091 14.818 1.00 49.30 ? 76 PRO A CA 1 ATOM 403 C C . PRO A 1 78 ? 163.702 98.696 13.505 1.00 53.59 ? 76 PRO A C 1 ATOM 404 O O . PRO A 1 78 ? 163.047 98.305 12.539 1.00 53.66 ? 76 PRO A O 1 ATOM 405 C CB . PRO A 1 78 ? 162.296 100.449 14.674 1.00 50.89 ? 76 PRO A CB 1 ATOM 406 C CG . PRO A 1 78 ? 163.331 101.430 15.098 1.00 54.96 ? 76 PRO A CG 1 ATOM 407 C CD . PRO A 1 78 ? 163.994 100.768 16.273 1.00 50.55 ? 76 PRO A CD 1 ATOM 408 N N . HIS A 1 79 ? 165.020 98.847 13.457 1.00 49.59 ? 77 HIS A N 1 ATOM 409 C CA . HIS A 1 79 ? 165.821 98.528 12.283 1.00 49.22 ? 77 HIS A CA 1 ATOM 410 C C . HIS A 1 79 ? 166.524 97.189 12.448 1.00 48.56 ? 77 HIS A C 1 ATOM 411 O O . HIS A 1 79 ? 167.036 96.660 11.469 1.00 48.50 ? 77 HIS A O 1 ATOM 412 C CB . HIS A 1 79 ? 166.858 99.635 12.035 1.00 51.25 ? 77 HIS A CB 1 ATOM 413 C CG . HIS A 1 79 ? 166.259 100.971 11.720 1.00 55.76 ? 77 HIS A CG 1 ATOM 414 N ND1 . HIS A 1 79 ? 166.218 101.988 12.666 1.00 57.95 ? 77 HIS A ND1 1 ATOM 415 C CD2 . HIS A 1 79 ? 165.689 101.412 10.570 1.00 58.08 ? 77 HIS A CD2 1 ATOM 416 C CE1 . HIS A 1 79 ? 165.643 103.014 12.057 1.00 57.61 ? 77 HIS A CE1 1 ATOM 417 N NE2 . HIS A 1 79 ? 165.303 102.712 10.795 1.00 57.95 ? 77 HIS A NE2 1 ATOM 418 N N . LEU A 1 80 ? 166.565 96.651 13.680 1.00 42.12 ? 78 LEU A N 1 ATOM 419 C CA . LEU A 1 80 ? 167.218 95.382 13.984 1.00 41.13 ? 78 LEU A CA 1 ATOM 420 C C . LEU A 1 80 ? 166.211 94.365 14.518 1.00 43.24 ? 78 LEU A C 1 ATOM 421 O O . LEU A 1 80 ? 165.743 94.506 15.656 1.00 43.56 ? 78 LEU A O 1 ATOM 422 C CB . LEU A 1 80 ? 168.380 95.609 14.972 1.00 41.17 ? 78 LEU A CB 1 ATOM 423 C CG . LEU A 1 80 ? 169.667 94.808 14.752 1.00 45.96 ? 78 LEU A CG 1 ATOM 424 C CD1 . LEU A 1 80 ? 170.113 94.796 13.256 1.00 46.14 ? 78 LEU A CD1 1 ATOM 425 C CD2 . LEU A 1 80 ? 170.772 95.344 15.627 1.00 46.87 ? 78 LEU A CD2 1 ATOM 426 N N . LEU A 1 81 ? 165.882 93.348 13.682 1.00 38.19 ? 79 LEU A N 1 ATOM 427 C CA . LEU A 1 81 ? 164.890 92.298 13.935 1.00 38.89 ? 79 LEU A CA 1 ATOM 428 C C . LEU A 1 81 ? 163.644 92.919 14.597 1.00 44.03 ? 79 LEU A C 1 ATOM 429 O O . LEU A 1 81 ? 163.385 92.624 15.770 1.00 43.97 ? 79 LEU A O 1 ATOM 430 C CB . LEU A 1 81 ? 165.456 91.165 14.827 1.00 39.48 ? 79 LEU A CB 1 ATOM 431 C CG . LEU A 1 81 ? 166.604 90.315 14.287 1.00 44.02 ? 79 LEU A CG 1 ATOM 432 C CD1 . LEU A 1 81 ? 167.473 89.816 15.441 1.00 44.05 ? 79 LEU A CD1 1 ATOM 433 C CD2 . LEU A 1 81 ? 166.083 89.160 13.441 1.00 44.20 ? 79 LEU A CD2 1 ATOM 434 N N . PRO A 1 82 ? 162.923 93.856 13.914 1.00 40.76 ? 80 PRO A N 1 ATOM 435 C CA . PRO A 1 82 ? 161.777 94.517 14.554 1.00 40.33 ? 80 PRO A CA 1 ATOM 436 C C . PRO A 1 82 ? 160.650 93.601 15.060 1.00 43.35 ? 80 PRO A C 1 ATOM 437 O O . PRO A 1 82 ? 159.968 93.971 16.012 1.00 43.36 ? 80 PRO A O 1 ATOM 438 C CB . PRO A 1 82 ? 161.283 95.486 13.463 1.00 42.12 ? 80 PRO A CB 1 ATOM 439 C CG . PRO A 1 82 ? 161.777 94.924 12.193 1.00 46.02 ? 80 PRO A CG 1 ATOM 440 C CD . PRO A 1 82 ? 163.124 94.393 12.549 1.00 42.11 ? 80 PRO A CD 1 ATOM 441 N N . GLY A 1 83 ? 160.462 92.436 14.453 1.00 38.78 ? 81 GLY A N 1 ATOM 442 C CA . GLY A 1 83 ? 159.410 91.524 14.899 1.00 38.85 ? 81 GLY A CA 1 ATOM 443 C C . GLY A 1 83 ? 159.873 90.259 15.598 1.00 43.59 ? 81 GLY A C 1 ATOM 444 O O . GLY A 1 83 ? 159.046 89.410 15.938 1.00 44.34 ? 81 GLY A O 1 ATOM 445 N N . VAL A 1 84 ? 161.204 90.098 15.794 1.00 38.41 ? 82 VAL A N 1 ATOM 446 C CA . VAL A 1 84 ? 161.813 88.922 16.421 1.00 36.06 ? 82 VAL A CA 1 ATOM 447 C C . VAL A 1 84 ? 162.561 89.346 17.692 1.00 42.21 ? 82 VAL A C 1 ATOM 448 O O . VAL A 1 84 ? 163.476 90.165 17.604 1.00 44.58 ? 82 VAL A O 1 ATOM 449 C CB . VAL A 1 84 ? 162.719 88.139 15.429 1.00 37.47 ? 82 VAL A CB 1 ATOM 450 C CG1 . VAL A 1 84 ? 163.204 86.831 16.034 1.00 37.08 ? 82 VAL A CG1 1 ATOM 451 C CG2 . VAL A 1 84 ? 162.011 87.875 14.097 1.00 36.68 ? 82 VAL A CG2 1 ATOM 452 N N . ARG A 1 85 ? 162.137 88.829 18.868 1.00 37.86 ? 83 ARG A N 1 ATOM 453 C CA . ARG A 1 85 ? 162.756 89.075 20.182 1.00 36.82 ? 83 ARG A CA 1 ATOM 454 C C . ARG A 1 85 ? 163.931 88.104 20.333 1.00 43.20 ? 83 ARG A C 1 ATOM 455 O O . ARG A 1 85 ? 163.800 86.901 20.045 1.00 43.59 ? 83 ARG A O 1 ATOM 456 C CB . ARG A 1 85 ? 161.751 88.843 21.326 1.00 33.48 ? 83 ARG A CB 1 ATOM 457 C CG . ARG A 1 85 ? 162.357 88.886 22.728 1.00 43.63 ? 83 ARG A CG 1 ATOM 458 C CD . ARG A 1 85 ? 161.363 89.284 23.801 1.00 54.73 ? 83 ARG A CD 1 ATOM 459 N NE . ARG A 1 85 ? 161.046 90.711 23.733 1.00 63.59 ? 83 ARG A NE 1 ATOM 460 C CZ . ARG A 1 85 ? 161.553 91.640 24.536 1.00 78.36 ? 83 ARG A CZ 1 ATOM 461 N NH1 . ARG A 1 85 ? 162.387 91.301 25.512 1.00 65.91 ? 83 ARG A NH1 1 ATOM 462 N NH2 . ARG A 1 85 ? 161.214 92.913 24.383 1.00 69.44 ? 83 ARG A NH2 1 ATOM 463 N N . LEU A 1 86 ? 165.080 88.638 20.781 1.00 38.89 ? 84 LEU A N 1 ATOM 464 C CA . LEU A 1 86 ? 166.276 87.847 21.012 1.00 37.14 ? 84 LEU A CA 1 ATOM 465 C C . LEU A 1 86 ? 166.361 87.569 22.493 1.00 38.44 ? 84 LEU A C 1 ATOM 466 O O . LEU A 1 86 ? 166.550 88.497 23.281 1.00 37.47 ? 84 LEU A O 1 ATOM 467 C CB . LEU A 1 86 ? 167.570 88.569 20.550 1.00 36.73 ? 84 LEU A CB 1 ATOM 468 C CG . LEU A 1 86 ? 167.998 88.457 19.105 1.00 40.91 ? 84 LEU A CG 1 ATOM 469 C CD1 . LEU A 1 86 ? 169.266 89.228 18.884 1.00 40.18 ? 84 LEU A CD1 1 ATOM 470 C CD2 . LEU A 1 86 ? 168.216 87.001 18.691 1.00 45.74 ? 84 LEU A CD2 1 ATOM 471 N N . GLY A 1 87 ? 166.204 86.303 22.850 1.00 33.79 ? 85 GLY A N 1 ATOM 472 C CA . GLY A 1 87 ? 166.363 85.847 24.217 1.00 33.99 ? 85 GLY A CA 1 ATOM 473 C C . GLY A 1 87 ? 167.829 85.566 24.500 1.00 38.36 ? 85 GLY A C 1 ATOM 474 O O . GLY A 1 87 ? 168.696 85.788 23.647 1.00 37.41 ? 85 GLY A O 1 ATOM 475 N N . ALA A 1 88 ? 168.118 85.072 25.699 1.00 35.35 ? 86 ALA A N 1 ATOM 476 C CA . ALA A 1 88 ? 169.473 84.755 26.124 1.00 35.29 ? 86 ALA A CA 1 ATOM 477 C C . ALA A 1 88 ? 169.462 83.553 27.038 1.00 41.06 ? 86 ALA A C 1 ATOM 478 O O . ALA A 1 88 ? 168.502 83.369 27.792 1.00 41.49 ? 86 ALA A O 1 ATOM 479 C CB . ALA A 1 88 ? 170.078 85.943 26.862 1.00 35.76 ? 86 ALA A CB 1 ATOM 480 N N . HIS A 1 89 ? 170.534 82.748 26.997 1.00 37.46 ? 87 HIS A N 1 ATOM 481 C CA . HIS A 1 89 ? 170.729 81.598 27.879 1.00 37.01 ? 87 HIS A CA 1 ATOM 482 C C . HIS A 1 89 ? 172.193 81.663 28.203 1.00 35.24 ? 87 HIS A C 1 ATOM 483 O O . HIS A 1 89 ? 173.015 81.140 27.466 1.00 35.17 ? 87 HIS A O 1 ATOM 484 C CB . HIS A 1 89 ? 170.306 80.296 27.192 1.00 39.60 ? 87 HIS A CB 1 ATOM 485 C CG . HIS A 1 89 ? 170.207 79.105 28.104 1.00 44.83 ? 87 HIS A CG 1 ATOM 486 N ND1 . HIS A 1 89 ? 168.981 78.497 28.373 1.00 47.36 ? 87 HIS A ND1 1 ATOM 487 C CD2 . HIS A 1 89 ? 171.190 78.396 28.716 1.00 47.44 ? 87 HIS A CD2 1 ATOM 488 C CE1 . HIS A 1 89 ? 169.259 77.467 29.163 1.00 47.18 ? 87 HIS A CE1 1 ATOM 489 N NE2 . HIS A 1 89 ? 170.575 77.362 29.393 1.00 47.56 ? 87 HIS A NE2 1 ATOM 490 N N . ILE A 1 90 ? 172.523 82.433 29.237 1.00 29.96 ? 88 ILE A N 1 ATOM 491 C CA . ILE A 1 90 ? 173.888 82.768 29.636 1.00 29.69 ? 88 ILE A CA 1 ATOM 492 C C . ILE A 1 90 ? 174.418 81.870 30.752 1.00 35.61 ? 88 ILE A C 1 ATOM 493 O O . ILE A 1 90 ? 173.711 81.595 31.720 1.00 36.00 ? 88 ILE A O 1 ATOM 494 C CB . ILE A 1 90 ? 174.015 84.284 29.975 1.00 31.99 ? 88 ILE A CB 1 ATOM 495 C CG1 . ILE A 1 90 ? 173.529 85.161 28.782 1.00 31.46 ? 88 ILE A CG1 1 ATOM 496 C CG2 . ILE A 1 90 ? 175.447 84.647 30.351 1.00 32.68 ? 88 ILE A CG2 1 ATOM 497 C CD1 . ILE A 1 90 ? 173.212 86.583 29.115 1.00 29.51 ? 88 ILE A CD1 1 ATOM 498 N N . LEU A 1 91 ? 175.695 81.424 30.593 1.00 31.26 ? 89 LEU A N 1 ATOM 499 C CA . LEU A 1 91 ? 176.379 80.512 31.494 1.00 29.61 ? 89 LEU A CA 1 ATOM 500 C C . LEU A 1 91 ? 177.685 81.036 32.024 1.00 33.71 ? 89 LEU A C 1 ATOM 501 O O . LEU A 1 91 ? 178.358 81.826 31.368 1.00 34.34 ? 89 LEU A O 1 ATOM 502 C CB . LEU A 1 91 ? 176.599 79.167 30.789 1.00 29.22 ? 89 LEU A CB 1 ATOM 503 C CG . LEU A 1 91 ? 175.370 78.528 30.133 1.00 32.58 ? 89 LEU A CG 1 ATOM 504 C CD1 . LEU A 1 91 ? 175.755 77.318 29.332 1.00 31.52 ? 89 LEU A CD1 1 ATOM 505 C CD2 . LEU A 1 91 ? 174.281 78.205 31.162 1.00 32.19 ? 89 LEU A CD2 1 ATOM 506 N N . ASP A 1 92 ? 178.045 80.597 33.226 1.00 30.04 ? 90 ASP A N 1 ATOM 507 C CA . ASP A 1 92 ? 179.303 80.967 33.852 1.00 29.32 ? 90 ASP A CA 1 ATOM 508 C C . ASP A 1 92 ? 180.296 79.862 33.461 1.00 37.27 ? 90 ASP A C 1 ATOM 509 O O . ASP A 1 92 ? 179.965 78.670 33.534 1.00 38.04 ? 90 ASP A O 1 ATOM 510 C CB . ASP A 1 92 ? 179.131 81.055 35.381 1.00 29.19 ? 90 ASP A CB 1 ATOM 511 C CG . ASP A 1 92 ? 180.316 81.543 36.218 1.00 35.52 ? 90 ASP A CG 1 ATOM 512 O OD1 . ASP A 1 92 ? 181.364 81.921 35.632 1.00 34.79 ? 90 ASP A OD1 1 ATOM 513 O OD2 . ASP A 1 92 ? 180.205 81.534 37.457 1.00 36.84 ? 90 ASP A OD2 1 ATOM 514 N N . SER A 1 93 ? 181.480 80.256 32.983 1.00 33.79 ? 91 SER A N 1 ATOM 515 C CA . SER A 1 93 ? 182.518 79.294 32.626 1.00 32.99 ? 91 SER A CA 1 ATOM 516 C C . SER A 1 93 ? 183.341 78.948 33.868 1.00 36.20 ? 91 SER A C 1 ATOM 517 O O . SER A 1 93 ? 183.973 77.894 33.883 1.00 34.09 ? 91 SER A O 1 ATOM 518 C CB . SER A 1 93 ? 183.434 79.857 31.543 1.00 33.88 ? 91 SER A CB 1 ATOM 519 O OG . SER A 1 93 ? 184.294 80.860 32.064 1.00 40.33 ? 91 SER A OG 1 ATOM 520 N N . CYS A 1 94 ? 183.348 79.850 34.893 1.00 35.04 ? 92 CYS A N 1 ATOM 521 C CA . CYS A 1 94 ? 184.168 79.763 36.115 1.00 37.65 ? 92 CYS A CA 1 ATOM 522 C C . CYS A 1 94 ? 185.641 79.751 35.762 1.00 37.59 ? 92 CYS A C 1 ATOM 523 O O . CYS A 1 94 ? 186.429 79.116 36.468 1.00 36.83 ? 92 CYS A O 1 ATOM 524 C CB . CYS A 1 94 ? 183.783 78.594 37.023 1.00 41.17 ? 92 CYS A CB 1 ATOM 525 S SG . CYS A 1 94 ? 182.097 78.696 37.649 1.00 47.75 ? 92 CYS A SG 1 ATOM 526 N N . SER A 1 95 ? 186.011 80.464 34.640 1.00 31.45 ? 93 SER A N 1 ATOM 527 C CA . SER A 1 95 ? 187.362 80.600 34.069 1.00 28.61 ? 93 SER A CA 1 ATOM 528 C C . SER A 1 95 ? 188.031 79.228 33.932 1.00 31.38 ? 93 SER A C 1 ATOM 529 O O . SER A 1 95 ? 189.200 79.080 34.272 1.00 31.64 ? 93 SER A O 1 ATOM 530 C CB . SER A 1 95 ? 188.192 81.511 34.961 1.00 29.39 ? 93 SER A CB 1 ATOM 531 O OG . SER A 1 95 ? 187.475 82.697 35.252 1.00 32.73 ? 93 SER A OG 1 ATOM 532 N N . LYS A 1 96 ? 187.264 78.200 33.503 1.00 27.02 ? 94 LYS A N 1 ATOM 533 C CA . LYS A 1 96 ? 187.726 76.818 33.448 1.00 26.23 ? 94 LYS A CA 1 ATOM 534 C C . LYS A 1 96 ? 187.045 76.051 32.329 1.00 31.29 ? 94 LYS A C 1 ATOM 535 O O . LYS A 1 96 ? 185.823 75.876 32.358 1.00 30.98 ? 94 LYS A O 1 ATOM 536 C CB . LYS A 1 96 ? 187.526 76.142 34.833 1.00 28.48 ? 94 LYS A CB 1 ATOM 537 C CG . LYS A 1 96 ? 188.099 74.716 34.945 1.00 44.95 ? 94 LYS A CG 1 ATOM 538 C CD . LYS A 1 96 ? 187.690 73.994 36.224 1.00 49.61 ? 94 LYS A CD 1 ATOM 539 C CE . LYS A 1 96 ? 188.796 73.947 37.255 1.00 61.69 ? 94 LYS A CE 1 ATOM 540 N NZ . LYS A 1 96 ? 188.301 74.181 38.651 1.00 72.00 ? 94 LYS A NZ 1 ATOM 541 N N . ASP A 1 97 ? 187.850 75.582 31.348 1.00 30.33 ? 95 ASP A N 1 ATOM 542 C CA . ASP A 1 97 ? 187.428 74.817 30.154 1.00 30.72 ? 95 ASP A CA 1 ATOM 543 C C . ASP A 1 97 ? 186.553 73.602 30.469 1.00 33.58 ? 95 ASP A C 1 ATOM 544 O O . ASP A 1 97 ? 185.566 73.367 29.753 1.00 33.48 ? 95 ASP A O 1 ATOM 545 C CB . ASP A 1 97 ? 188.634 74.405 29.283 1.00 33.32 ? 95 ASP A CB 1 ATOM 546 C CG . ASP A 1 97 ? 189.628 73.393 29.859 1.00 54.50 ? 95 ASP A CG 1 ATOM 547 O OD1 . ASP A 1 97 ? 189.689 73.253 31.110 1.00 57.64 ? 95 ASP A OD1 1 ATOM 548 O OD2 . ASP A 1 97 ? 190.390 72.787 29.062 1.00 63.73 ? 95 ASP A OD2 1 ATOM 549 N N . THR A 1 98 ? 186.881 72.865 31.557 1.00 28.27 ? 96 THR A N 1 ATOM 550 C CA . THR A 1 98 ? 186.111 71.691 31.982 1.00 27.60 ? 96 THR A CA 1 ATOM 551 C C . THR A 1 98 ? 184.751 72.101 32.486 1.00 32.32 ? 96 THR A C 1 ATOM 552 O O . THR A 1 98 ? 183.765 71.498 32.041 1.00 33.55 ? 96 THR A O 1 ATOM 553 C CB . THR A 1 98 ? 186.872 70.779 32.954 1.00 32.47 ? 96 THR A CB 1 ATOM 554 O OG1 . THR A 1 98 ? 187.711 71.555 33.808 1.00 41.26 ? 96 THR A OG1 1 ATOM 555 C CG2 . THR A 1 98 ? 187.736 69.808 32.243 1.00 29.61 ? 96 THR A CG2 1 ATOM 556 N N . HIS A 1 99 ? 184.675 73.142 33.370 1.00 27.97 ? 97 HIS A N 1 ATOM 557 C CA . HIS A 1 99 ? 183.395 73.642 33.885 1.00 27.85 ? 97 HIS A CA 1 ATOM 558 C C . HIS A 1 99 ? 182.575 74.175 32.718 1.00 30.56 ? 97 HIS A C 1 ATOM 559 O O . HIS A 1 99 ? 181.438 73.735 32.524 1.00 30.75 ? 97 HIS A O 1 ATOM 560 C CB . HIS A 1 99 ? 183.590 74.734 34.944 1.00 29.68 ? 97 HIS A CB 1 ATOM 561 C CG . HIS A 1 99 ? 182.299 75.203 35.546 1.00 33.94 ? 97 HIS A CG 1 ATOM 562 N ND1 . HIS A 1 99 ? 181.816 74.667 36.717 1.00 36.11 ? 97 HIS A ND1 1 ATOM 563 C CD2 . HIS A 1 99 ? 181.407 76.109 35.086 1.00 36.56 ? 97 HIS A CD2 1 ATOM 564 C CE1 . HIS A 1 99 ? 180.660 75.261 36.941 1.00 35.47 ? 97 HIS A CE1 1 ATOM 565 N NE2 . HIS A 1 99 ? 180.367 76.130 35.986 1.00 36.14 ? 97 HIS A NE2 1 ATOM 566 N N . ALA A 1 100 ? 183.172 75.078 31.902 1.00 24.92 ? 98 ALA A N 1 ATOM 567 C CA . ALA A 1 100 ? 182.504 75.653 30.738 1.00 24.22 ? 98 ALA A CA 1 ATOM 568 C C . ALA A 1 100 ? 181.858 74.584 29.812 1.00 28.09 ? 98 ALA A C 1 ATOM 569 O O . ALA A 1 100 ? 180.757 74.787 29.319 1.00 26.08 ? 98 ALA A O 1 ATOM 570 C CB . ALA A 1 100 ? 183.486 76.497 29.952 1.00 24.46 ? 98 ALA A CB 1 ATOM 571 N N . LEU A 1 101 ? 182.544 73.464 29.588 1.00 27.27 ? 99 LEU A N 1 ATOM 572 C CA . LEU A 1 101 ? 182.058 72.426 28.694 1.00 28.94 ? 99 LEU A CA 1 ATOM 573 C C . LEU A 1 101 ? 180.856 71.646 29.266 1.00 33.30 ? 99 LEU A C 1 ATOM 574 O O . LEU A 1 101 ? 179.953 71.322 28.482 1.00 33.84 ? 99 LEU A O 1 ATOM 575 C CB . LEU A 1 101 ? 183.195 71.497 28.243 1.00 29.54 ? 99 LEU A CB 1 ATOM 576 C CG . LEU A 1 101 ? 182.903 70.678 26.982 1.00 35.89 ? 99 LEU A CG 1 ATOM 577 C CD1 . LEU A 1 101 ? 182.861 71.554 25.760 1.00 36.56 ? 99 LEU A CD1 1 ATOM 578 C CD2 . LEU A 1 101 ? 183.893 69.531 26.811 1.00 38.80 ? 99 LEU A CD2 1 ATOM 579 N N . GLU A 1 102 ? 180.819 71.384 30.613 1.00 27.48 ? 100 GLU A N 1 ATOM 580 C CA . GLU A 1 102 ? 179.684 70.729 31.273 1.00 26.98 ? 100 GLU A CA 1 ATOM 581 C C . GLU A 1 102 ? 178.482 71.656 31.132 1.00 34.39 ? 100 GLU A C 1 ATOM 582 O O . GLU A 1 102 ? 177.380 71.206 30.789 1.00 35.84 ? 100 GLU A O 1 ATOM 583 C CB . GLU A 1 102 ? 179.941 70.495 32.764 1.00 28.21 ? 100 GLU A CB 1 ATOM 584 C CG . GLU A 1 102 ? 181.197 69.718 33.112 1.00 36.75 ? 100 GLU A CG 1 ATOM 585 C CD . GLU A 1 102 ? 181.830 70.004 34.462 1.00 53.41 ? 100 GLU A CD 1 ATOM 586 O OE1 . GLU A 1 102 ? 181.354 70.905 35.197 1.00 53.71 ? 100 GLU A OE1 1 ATOM 587 O OE2 . GLU A 1 102 ? 182.834 69.326 34.771 1.00 46.31 ? 100 GLU A OE2 1 ATOM 588 N N . GLN A 1 103 ? 178.707 72.962 31.376 1.00 31.85 ? 101 GLN A N 1 ATOM 589 C CA . GLN A 1 103 ? 177.704 74.026 31.237 1.00 31.30 ? 101 GLN A CA 1 ATOM 590 C C . GLN A 1 103 ? 177.190 74.117 29.809 1.00 35.56 ? 101 GLN A C 1 ATOM 591 O O . GLN A 1 103 ? 175.981 74.194 29.616 1.00 35.40 ? 101 GLN A O 1 ATOM 592 C CB . GLN A 1 103 ? 178.266 75.389 31.673 1.00 31.89 ? 101 GLN A CB 1 ATOM 593 C CG . GLN A 1 103 ? 178.488 75.536 33.170 1.00 34.21 ? 101 GLN A CG 1 ATOM 594 C CD . GLN A 1 103 ? 177.274 75.150 33.983 1.00 48.87 ? 101 GLN A CD 1 ATOM 595 O OE1 . GLN A 1 103 ? 176.192 75.749 33.890 1.00 44.91 ? 101 GLN A OE1 1 ATOM 596 N NE2 . GLN A 1 103 ? 177.428 74.108 34.772 1.00 41.39 ? 101 GLN A NE2 1 ATOM 597 N N . ALA A 1 104 ? 178.102 74.069 28.812 1.00 33.05 ? 102 ALA A N 1 ATOM 598 C CA . ALA A 1 104 ? 177.801 74.177 27.376 1.00 32.52 ? 102 ALA A CA 1 ATOM 599 C C . ALA A 1 104 ? 176.872 73.088 26.843 1.00 33.59 ? 102 ALA A C 1 ATOM 600 O O . ALA A 1 104 ? 176.274 73.286 25.800 1.00 31.37 ? 102 ALA A O 1 ATOM 601 C CB . ALA A 1 104 ? 179.090 74.237 26.568 1.00 33.55 ? 102 ALA A CB 1 ATOM 602 N N . LEU A 1 105 ? 176.717 71.958 27.565 1.00 31.70 ? 103 LEU A N 1 ATOM 603 C CA . LEU A 1 105 ? 175.775 70.897 27.188 1.00 31.66 ? 103 LEU A CA 1 ATOM 604 C C . LEU A 1 105 ? 174.362 71.458 27.084 1.00 38.60 ? 103 LEU A C 1 ATOM 605 O O . LEU A 1 105 ? 173.608 70.998 26.229 1.00 38.12 ? 103 LEU A O 1 ATOM 606 C CB . LEU A 1 105 ? 175.787 69.725 28.186 1.00 31.17 ? 103 LEU A CB 1 ATOM 607 C CG . LEU A 1 105 ? 176.925 68.679 28.083 1.00 32.93 ? 103 LEU A CG 1 ATOM 608 C CD1 . LEU A 1 105 ? 176.663 67.532 29.030 1.00 30.09 ? 103 LEU A CD1 1 ATOM 609 C CD2 . LEU A 1 105 ? 177.066 68.130 26.656 1.00 33.66 ? 103 LEU A CD2 1 ATOM 610 N N . ASP A 1 106 ? 174.029 72.508 27.911 1.00 37.69 ? 104 ASP A N 1 ATOM 611 C CA . ASP A 1 106 ? 172.752 73.246 27.899 1.00 38.23 ? 104 ASP A CA 1 ATOM 612 C C . ASP A 1 106 ? 172.421 73.853 26.515 1.00 41.59 ? 104 ASP A C 1 ATOM 613 O O . ASP A 1 106 ? 171.243 73.976 26.183 1.00 44.19 ? 104 ASP A O 1 ATOM 614 C CB . ASP A 1 106 ? 172.751 74.359 28.941 1.00 41.42 ? 104 ASP A CB 1 ATOM 615 C CG . ASP A 1 106 ? 172.233 73.932 30.295 1.00 66.06 ? 104 ASP A CG 1 ATOM 616 O OD1 . ASP A 1 106 ? 172.929 73.131 30.977 1.00 68.79 ? 104 ASP A OD1 1 ATOM 617 O OD2 . ASP A 1 106 ? 171.149 74.427 30.699 1.00 75.41 ? 104 ASP A OD2 1 ATOM 618 N N . PHE A 1 107 ? 173.444 74.213 25.719 1.00 33.93 ? 105 PHE A N 1 ATOM 619 C CA . PHE A 1 107 ? 173.284 74.791 24.388 1.00 31.86 ? 105 PHE A CA 1 ATOM 620 C C . PHE A 1 107 ? 172.952 73.764 23.366 1.00 39.92 ? 105 PHE A C 1 ATOM 621 O O . PHE A 1 107 ? 172.411 74.113 22.315 1.00 40.50 ? 105 PHE A O 1 ATOM 622 C CB . PHE A 1 107 ? 174.578 75.481 23.920 1.00 31.56 ? 105 PHE A CB 1 ATOM 623 C CG . PHE A 1 107 ? 175.106 76.605 24.764 1.00 30.95 ? 105 PHE A CG 1 ATOM 624 C CD1 . PHE A 1 107 ? 174.239 77.492 25.394 1.00 32.69 ? 105 PHE A CD1 1 ATOM 625 C CD2 . PHE A 1 107 ? 176.476 76.809 24.893 1.00 32.14 ? 105 PHE A CD2 1 ATOM 626 C CE1 . PHE A 1 107 ? 174.730 78.555 26.153 1.00 34.04 ? 105 PHE A CE1 1 ATOM 627 C CE2 . PHE A 1 107 ? 176.971 77.879 25.638 1.00 34.94 ? 105 PHE A CE2 1 ATOM 628 C CZ . PHE A 1 107 ? 176.096 78.752 26.260 1.00 33.50 ? 105 PHE A CZ 1 ATOM 629 N N . VAL A 1 108 ? 173.374 72.520 23.603 1.00 39.36 ? 106 VAL A N 1 ATOM 630 C CA . VAL A 1 108 ? 173.218 71.452 22.614 1.00 40.37 ? 106 VAL A CA 1 ATOM 631 C C . VAL A 1 108 ? 172.178 70.396 22.992 1.00 49.28 ? 106 VAL A C 1 ATOM 632 O O . VAL A 1 108 ? 171.828 69.602 22.117 1.00 50.42 ? 106 VAL A O 1 ATOM 633 C CB . VAL A 1 108 ? 174.572 70.779 22.235 1.00 42.88 ? 106 VAL A CB 1 ATOM 634 C CG1 . VAL A 1 108 ? 175.641 71.814 21.900 1.00 41.96 ? 106 VAL A CG1 1 ATOM 635 C CG2 . VAL A 1 108 ? 175.061 69.821 23.323 1.00 42.69 ? 106 VAL A CG2 1 ATOM 636 N N . ARG A 1 109 ? 171.699 70.367 24.263 1.00 47.64 ? 107 ARG A N 1 ATOM 637 C CA . ARG A 1 109 ? 170.743 69.357 24.742 1.00 48.59 ? 107 ARG A CA 1 ATOM 638 C C . ARG A 1 109 ? 169.426 69.260 23.924 1.00 55.33 ? 107 ARG A C 1 ATOM 639 O O . ARG A 1 109 ? 168.927 68.154 23.731 1.00 55.46 ? 107 ARG A O 1 ATOM 640 C CB . ARG A 1 109 ? 170.449 69.514 26.234 1.00 48.11 ? 107 ARG A CB 1 ATOM 641 C CG . ARG A 1 109 ? 170.904 68.280 26.987 1.00 55.53 ? 107 ARG A CG 1 ATOM 642 C CD . ARG A 1 109 ? 170.398 68.244 28.413 1.00 62.20 ? 107 ARG A CD 1 ATOM 643 N NE . ARG A 1 109 ? 171.486 68.043 29.374 1.00 58.89 ? 107 ARG A NE 1 ATOM 644 C CZ . ARG A 1 109 ? 172.188 69.029 29.926 1.00 69.48 ? 107 ARG A CZ 1 ATOM 645 N NH1 . ARG A 1 109 ? 173.150 68.758 30.794 1.00 60.09 ? 107 ARG A NH1 1 ATOM 646 N NH2 . ARG A 1 109 ? 171.935 70.294 29.608 1.00 53.65 ? 107 ARG A NH2 1 ATOM 647 N N . ALA A 1 110 ? 168.907 70.372 23.386 1.00 53.49 ? 108 ALA A N 1 ATOM 648 C CA . ALA A 1 110 ? 167.698 70.328 22.555 1.00 53.79 ? 108 ALA A CA 1 ATOM 649 C C . ALA A 1 110 ? 168.024 69.832 21.125 1.00 59.86 ? 108 ALA A C 1 ATOM 650 O O . ALA A 1 110 ? 167.588 70.451 20.148 1.00 60.11 ? 108 ALA A O 1 ATOM 651 C CB . ALA A 1 110 ? 167.051 71.708 22.508 1.00 54.42 ? 108 ALA A CB 1 ATOM 652 N N . SER A 1 111 ? 168.822 68.729 21.005 1.00 56.69 ? 109 SER A N 1 ATOM 653 C CA . SER A 1 111 ? 169.272 68.120 19.736 1.00 66.49 ? 109 SER A CA 1 ATOM 654 C C . SER A 1 111 ? 169.604 66.631 19.920 1.00 93.08 ? 109 SER A C 1 ATOM 655 O O . SER A 1 111 ? 170.230 66.237 20.908 1.00 58.07 ? 109 SER A O 1 ATOM 656 C CB . SER A 1 111 ? 170.490 68.850 19.169 1.00 69.05 ? 109 SER A CB 1 ATOM 657 O OG . SER A 1 111 ? 170.436 70.268 19.273 1.00 74.98 ? 109 SER A OG 1 ATOM 658 N N . THR A 1 136 ? 164.690 73.938 24.573 1.00 62.61 ? 134 THR A N 1 ATOM 659 C CA . THR A 1 136 ? 164.758 75.221 23.853 1.00 61.90 ? 134 THR A CA 1 ATOM 660 C C . THR A 1 136 ? 166.083 75.363 23.062 1.00 60.93 ? 134 THR A C 1 ATOM 661 O O . THR A 1 136 ? 167.178 75.369 23.640 1.00 59.81 ? 134 THR A O 1 ATOM 662 C CB . THR A 1 136 ? 164.463 76.438 24.773 1.00 74.05 ? 134 THR A CB 1 ATOM 663 O OG1 . THR A 1 136 ? 165.236 76.346 25.973 1.00 77.01 ? 134 THR A OG1 1 ATOM 664 C CG2 . THR A 1 136 ? 162.972 76.586 25.109 1.00 71.14 ? 134 THR A CG2 1 ATOM 665 N N . ALA A 1 137 ? 165.944 75.445 21.724 1.00 53.45 ? 135 ALA A N 1 ATOM 666 C CA . ALA A 1 137 ? 167.010 75.575 20.740 1.00 50.77 ? 135 ALA A CA 1 ATOM 667 C C . ALA A 1 137 ? 167.818 76.870 20.910 1.00 49.00 ? 135 ALA A C 1 ATOM 668 O O . ALA A 1 137 ? 167.250 77.937 21.197 1.00 47.04 ? 135 ALA A O 1 ATOM 669 C CB . ALA A 1 137 ? 166.418 75.517 19.345 1.00 51.45 ? 135 ALA A CB 1 ATOM 670 N N . ILE A 1 138 ? 169.157 76.753 20.745 1.00 41.76 ? 136 ILE A N 1 ATOM 671 C CA . ILE A 1 138 ? 170.105 77.869 20.827 1.00 39.16 ? 136 ILE A CA 1 ATOM 672 C C . ILE A 1 138 ? 170.477 78.223 19.396 1.00 39.60 ? 136 ILE A C 1 ATOM 673 O O . ILE A 1 138 ? 170.850 77.337 18.627 1.00 38.08 ? 136 ILE A O 1 ATOM 674 C CB . ILE A 1 138 ? 171.322 77.535 21.744 1.00 41.13 ? 136 ILE A CB 1 ATOM 675 C CG1 . ILE A 1 138 ? 170.875 77.161 23.178 1.00 41.61 ? 136 ILE A CG1 1 ATOM 676 C CG2 . ILE A 1 138 ? 172.356 78.655 21.776 1.00 40.30 ? 136 ILE A CG2 1 ATOM 677 C CD1 . ILE A 1 138 ? 170.154 78.242 24.019 1.00 45.73 ? 136 ILE A CD1 1 ATOM 678 N N . THR A 1 139 ? 170.304 79.492 19.010 1.00 35.46 ? 137 THR A N 1 ATOM 679 C CA . THR A 1 139 ? 170.590 79.867 17.624 1.00 35.29 ? 137 THR A CA 1 ATOM 680 C C . THR A 1 139 ? 172.099 80.095 17.395 1.00 37.33 ? 137 THR A C 1 ATOM 681 O O . THR A 1 139 ? 172.629 79.693 16.354 1.00 38.46 ? 137 THR A O 1 ATOM 682 C CB . THR A 1 139 ? 169.698 81.035 17.189 1.00 41.27 ? 137 THR A CB 1 ATOM 683 O OG1 . THR A 1 139 ? 168.350 80.558 17.216 1.00 41.73 ? 137 THR A OG1 1 ATOM 684 C CG2 . THR A 1 139 ? 170.002 81.508 15.769 1.00 37.21 ? 137 THR A CG2 1 ATOM 685 N N . GLY A 1 140 ? 172.756 80.720 18.364 1.00 28.91 ? 138 GLY A N 1 ATOM 686 C CA . GLY A 1 140 ? 174.168 81.035 18.292 1.00 27.33 ? 138 GLY A CA 1 ATOM 687 C C . GLY A 1 140 ? 174.701 81.385 19.659 1.00 28.83 ? 138 GLY A C 1 ATOM 688 O O . GLY A 1 140 ? 173.919 81.710 20.559 1.00 28.72 ? 138 GLY A O 1 ATOM 689 N N . VAL A 1 141 ? 176.030 81.282 19.841 1.00 21.53 ? 139 VAL A N 1 ATOM 690 C CA . VAL A 1 141 ? 176.654 81.535 21.134 1.00 19.18 ? 139 VAL A CA 1 ATOM 691 C C . VAL A 1 141 ? 177.578 82.747 21.126 1.00 22.81 ? 139 VAL A C 1 ATOM 692 O O . VAL A 1 141 ? 178.315 82.964 20.169 1.00 25.09 ? 139 VAL A O 1 ATOM 693 C CB . VAL A 1 141 ? 177.360 80.269 21.672 1.00 21.46 ? 139 VAL A CB 1 ATOM 694 C CG1 . VAL A 1 141 ? 177.946 80.524 23.055 1.00 20.98 ? 139 VAL A CG1 1 ATOM 695 C CG2 . VAL A 1 141 ? 176.406 79.055 21.697 1.00 20.35 ? 139 VAL A CG2 1 ATOM 696 N N . ILE A 1 142 ? 177.500 83.557 22.181 1.00 17.29 ? 140 ILE A N 1 ATOM 697 C CA . ILE A 1 142 ? 178.367 84.707 22.405 1.00 16.06 ? 140 ILE A CA 1 ATOM 698 C C . ILE A 1 142 ? 179.393 84.289 23.470 1.00 22.47 ? 140 ILE A C 1 ATOM 699 O O . ILE A 1 142 ? 179.024 84.090 24.623 1.00 22.34 ? 140 ILE A O 1 ATOM 700 C CB . ILE A 1 142 ? 177.577 85.970 22.843 1.00 17.87 ? 140 ILE A CB 1 ATOM 701 C CG1 . ILE A 1 142 ? 176.493 86.364 21.816 1.00 16.31 ? 140 ILE A CG1 1 ATOM 702 C CG2 . ILE A 1 142 ? 178.521 87.171 23.207 1.00 18.00 ? 140 ILE A CG2 1 ATOM 703 C CD1 . ILE A 1 142 ? 176.942 86.580 20.361 1.00 24.42 ? 140 ILE A CD1 1 ATOM 704 N N . GLY A 1 143 ? 180.655 84.137 23.065 1.00 21.23 ? 141 GLY A N 1 ATOM 705 C CA . GLY A 1 143 ? 181.741 83.788 23.978 1.00 21.53 ? 141 GLY A CA 1 ATOM 706 C C . GLY A 1 143 ? 182.645 82.642 23.559 1.00 24.40 ? 141 GLY A C 1 ATOM 707 O O . GLY A 1 143 ? 182.517 82.131 22.442 1.00 24.29 ? 141 GLY A O 1 ATOM 708 N N . GLY A 1 144 ? 183.545 82.220 24.457 1.00 17.54 ? 142 GLY A N 1 ATOM 709 C CA . GLY A 1 144 ? 183.742 82.831 25.765 1.00 16.24 ? 142 GLY A CA 1 ATOM 710 C C . GLY A 1 144 ? 184.880 83.824 25.782 1.00 22.04 ? 142 GLY A C 1 ATOM 711 O O . GLY A 1 144 ? 185.144 84.489 24.784 1.00 23.99 ? 142 GLY A O 1 ATOM 712 N N . SER A 1 145 ? 185.555 83.943 26.902 1.00 19.52 ? 143 SER A N 1 ATOM 713 C CA . SER A 1 145 ? 186.662 84.880 27.060 1.00 20.09 ? 143 SER A CA 1 ATOM 714 C C . SER A 1 145 ? 187.988 84.193 26.809 1.00 26.57 ? 143 SER A C 1 ATOM 715 O O . SER A 1 145 ? 188.714 84.560 25.885 1.00 29.08 ? 143 SER A O 1 ATOM 716 C CB . SER A 1 145 ? 186.658 85.467 28.465 1.00 22.96 ? 143 SER A CB 1 ATOM 717 O OG . SER A 1 145 ? 185.504 86.264 28.629 1.00 32.28 ? 143 SER A OG 1 ATOM 718 N N . TYR A 1 146 ? 188.315 83.216 27.662 1.00 20.96 ? 144 TYR A N 1 ATOM 719 C CA . TYR A 1 146 ? 189.526 82.419 27.614 1.00 19.30 ? 144 TYR A CA 1 ATOM 720 C C . TYR A 1 146 ? 189.499 81.549 26.374 1.00 22.44 ? 144 TYR A C 1 ATOM 721 O O . TYR A 1 146 ? 188.477 80.925 26.080 1.00 21.71 ? 144 TYR A O 1 ATOM 722 C CB . TYR A 1 146 ? 189.598 81.533 28.864 1.00 19.86 ? 144 TYR A CB 1 ATOM 723 C CG . TYR A 1 146 ? 189.920 82.250 30.152 1.00 20.11 ? 144 TYR A CG 1 ATOM 724 C CD1 . TYR A 1 146 ? 191.231 82.559 30.489 1.00 21.11 ? 144 TYR A CD1 1 ATOM 725 C CD2 . TYR A 1 146 ? 188.914 82.604 31.046 1.00 21.56 ? 144 TYR A CD2 1 ATOM 726 C CE1 . TYR A 1 146 ? 191.542 83.221 31.675 1.00 20.72 ? 144 TYR A CE1 1 ATOM 727 C CE2 . TYR A 1 146 ? 189.206 83.292 32.224 1.00 23.03 ? 144 TYR A CE2 1 ATOM 728 C CZ . TYR A 1 146 ? 190.530 83.557 32.562 1.00 32.54 ? 144 TYR A CZ 1 ATOM 729 O OH . TYR A 1 146 ? 190.845 84.197 33.755 1.00 31.68 ? 144 TYR A OH 1 ATOM 730 N N . SER A 1 147 ? 190.630 81.492 25.654 1.00 21.04 ? 145 SER A N 1 ATOM 731 C CA . SER A 1 147 ? 190.776 80.656 24.433 1.00 21.06 ? 145 SER A CA 1 ATOM 732 C C . SER A 1 147 ? 190.521 79.158 24.681 1.00 25.71 ? 145 SER A C 1 ATOM 733 O O . SER A 1 147 ? 189.756 78.564 23.939 1.00 26.79 ? 145 SER A O 1 ATOM 734 C CB . SER A 1 147 ? 192.124 80.881 23.762 1.00 19.78 ? 145 SER A CB 1 ATOM 735 O OG . SER A 1 147 ? 192.094 82.102 23.046 1.00 20.54 ? 145 SER A OG 1 ATOM 736 N N . ASP A 1 148 ? 191.053 78.598 25.781 1.00 21.60 ? 146 ASP A N 1 ATOM 737 C CA . ASP A 1 148 ? 190.845 77.204 26.171 1.00 21.90 ? 146 ASP A CA 1 ATOM 738 C C . ASP A 1 148 ? 189.346 76.929 26.236 1.00 26.45 ? 146 ASP A C 1 ATOM 739 O O . ASP A 1 148 ? 188.885 75.909 25.724 1.00 25.18 ? 146 ASP A O 1 ATOM 740 C CB . ASP A 1 148 ? 191.556 76.879 27.516 1.00 24.53 ? 146 ASP A CB 1 ATOM 741 C CG . ASP A 1 148 ? 191.033 77.572 28.772 1.00 52.17 ? 146 ASP A CG 1 ATOM 742 O OD1 . ASP A 1 148 ? 190.539 78.715 28.658 1.00 57.62 ? 146 ASP A OD1 1 ATOM 743 O OD2 . ASP A 1 148 ? 191.146 76.977 29.883 1.00 60.54 ? 146 ASP A OD2 1 ATOM 744 N N . VAL A 1 149 ? 188.577 77.917 26.754 1.00 23.50 ? 147 VAL A N 1 ATOM 745 C CA . VAL A 1 149 ? 187.129 77.816 26.901 1.00 22.49 ? 147 VAL A CA 1 ATOM 746 C C . VAL A 1 149 ? 186.463 77.851 25.530 1.00 24.53 ? 147 VAL A C 1 ATOM 747 O O . VAL A 1 149 ? 185.683 76.949 25.238 1.00 23.81 ? 147 VAL A O 1 ATOM 748 C CB . VAL A 1 149 ? 186.584 78.883 27.891 1.00 25.97 ? 147 VAL A CB 1 ATOM 749 C CG1 . VAL A 1 149 ? 185.069 79.090 27.752 1.00 25.48 ? 147 VAL A CG1 1 ATOM 750 C CG2 . VAL A 1 149 ? 186.982 78.558 29.331 1.00 25.20 ? 147 VAL A CG2 1 ATOM 751 N N . SER A 1 150 ? 186.816 78.844 24.677 1.00 18.91 ? 148 SER A N 1 ATOM 752 C CA . SER A 1 150 ? 186.237 78.958 23.348 1.00 18.24 ? 148 SER A CA 1 ATOM 753 C C . SER A 1 150 ? 186.601 77.788 22.454 1.00 26.08 ? 148 SER A C 1 ATOM 754 O O . SER A 1 150 ? 185.836 77.468 21.553 1.00 27.74 ? 148 SER A O 1 ATOM 755 C CB . SER A 1 150 ? 186.648 80.261 22.682 1.00 19.01 ? 148 SER A CB 1 ATOM 756 O OG . SER A 1 150 ? 186.107 81.390 23.352 1.00 19.62 ? 148 SER A OG 1 ATOM 757 N N . ILE A 1 151 ? 187.761 77.158 22.682 1.00 22.80 ? 149 ILE A N 1 ATOM 758 C CA . ILE A 1 151 ? 188.206 76.033 21.876 1.00 23.37 ? 149 ILE A CA 1 ATOM 759 C C . ILE A 1 151 ? 187.396 74.774 22.219 1.00 27.61 ? 149 ILE A C 1 ATOM 760 O O . ILE A 1 151 ? 186.953 74.047 21.311 1.00 26.03 ? 149 ILE A O 1 ATOM 761 C CB . ILE A 1 151 ? 189.758 75.845 21.952 1.00 26.01 ? 149 ILE A CB 1 ATOM 762 C CG1 . ILE A 1 151 ? 190.426 76.924 21.097 1.00 26.43 ? 149 ILE A CG1 1 ATOM 763 C CG2 . ILE A 1 151 ? 190.206 74.442 21.487 1.00 22.85 ? 149 ILE A CG2 1 ATOM 764 C CD1 . ILE A 1 151 ? 191.840 77.137 21.362 1.00 32.30 ? 149 ILE A CD1 1 ATOM 765 N N . GLN A 1 152 ? 187.198 74.534 23.526 1.00 24.20 ? 150 GLN A N 1 ATOM 766 C CA . GLN A 1 152 ? 186.442 73.385 24.006 1.00 24.54 ? 150 GLN A CA 1 ATOM 767 C C . GLN A 1 152 ? 185.007 73.458 23.559 1.00 26.33 ? 150 GLN A C 1 ATOM 768 O O . GLN A 1 152 ? 184.464 72.477 23.034 1.00 26.35 ? 150 GLN A O 1 ATOM 769 C CB . GLN A 1 152 ? 186.541 73.276 25.530 1.00 27.09 ? 150 GLN A CB 1 ATOM 770 C CG . GLN A 1 152 ? 187.931 72.861 26.010 1.00 42.92 ? 150 GLN A CG 1 ATOM 771 C CD . GLN A 1 152 ? 188.201 71.452 25.638 1.00 66.44 ? 150 GLN A CD 1 ATOM 772 O OE1 . GLN A 1 152 ? 187.820 70.536 26.373 1.00 72.64 ? 150 GLN A OE1 1 ATOM 773 N NE2 . GLN A 1 152 ? 188.775 71.252 24.444 1.00 45.46 ? 150 GLN A NE2 1 ATOM 774 N N . VAL A 1 153 ? 184.440 74.660 23.663 1.00 21.02 ? 151 VAL A N 1 ATOM 775 C CA . VAL A 1 153 ? 183.079 74.974 23.283 1.00 20.54 ? 151 VAL A CA 1 ATOM 776 C C . VAL A 1 153 ? 182.899 74.883 21.786 1.00 25.04 ? 151 VAL A C 1 ATOM 777 O O . VAL A 1 153 ? 181.928 74.277 21.349 1.00 26.98 ? 151 VAL A O 1 ATOM 778 C CB . VAL A 1 153 ? 182.643 76.320 23.897 1.00 24.66 ? 151 VAL A CB 1 ATOM 779 C CG1 . VAL A 1 153 ? 181.318 76.791 23.321 1.00 25.10 ? 151 VAL A CG1 1 ATOM 780 C CG2 . VAL A 1 153 ? 182.539 76.192 25.421 1.00 23.94 ? 151 VAL A CG2 1 ATOM 781 N N . ALA A 1 154 ? 183.868 75.348 21.005 1.00 21.87 ? 152 ALA A N 1 ATOM 782 C CA . ALA A 1 154 ? 183.810 75.261 19.532 1.00 21.36 ? 152 ALA A CA 1 ATOM 783 C C . ALA A 1 154 ? 183.832 73.831 19.057 1.00 24.21 ? 152 ALA A C 1 ATOM 784 O O . ALA A 1 154 ? 183.134 73.512 18.085 1.00 24.08 ? 152 ALA A O 1 ATOM 785 C CB . ALA A 1 154 ? 184.949 76.047 18.881 1.00 21.81 ? 152 ALA A CB 1 ATOM 786 N N . ASN A 1 155 ? 184.635 72.964 19.725 1.00 19.00 ? 153 ASN A N 1 ATOM 787 C CA . ASN A 1 155 ? 184.703 71.540 19.350 1.00 18.48 ? 153 ASN A CA 1 ATOM 788 C C . ASN A 1 155 ? 183.336 70.923 19.526 1.00 24.43 ? 153 ASN A C 1 ATOM 789 O O . ASN A 1 155 ? 182.951 70.132 18.693 1.00 26.42 ? 153 ASN A O 1 ATOM 790 C CB . ASN A 1 155 ? 185.748 70.759 20.160 1.00 14.40 ? 153 ASN A CB 1 ATOM 791 C CG . ASN A 1 155 ? 187.176 71.176 19.933 1.00 22.76 ? 153 ASN A CG 1 ATOM 792 O OD1 . ASN A 1 155 ? 187.581 71.609 18.856 1.00 14.08 ? 153 ASN A OD1 1 ATOM 793 N ND2 . ASN A 1 155 ? 187.964 71.115 20.966 1.00 20.97 ? 153 ASN A ND2 1 ATOM 794 N N . LEU A 1 156 ? 182.573 71.366 20.546 1.00 22.22 ? 154 LEU A N 1 ATOM 795 C CA . LEU A 1 156 ? 181.213 70.918 20.858 1.00 22.83 ? 154 LEU A CA 1 ATOM 796 C C . LEU A 1 156 ? 180.127 71.456 19.922 1.00 28.25 ? 154 LEU A C 1 ATOM 797 O O . LEU A 1 156 ? 179.321 70.661 19.426 1.00 27.99 ? 154 LEU A O 1 ATOM 798 C CB . LEU A 1 156 ? 180.838 71.257 22.324 1.00 22.28 ? 154 LEU A CB 1 ATOM 799 C CG . LEU A 1 156 ? 179.506 70.670 22.833 1.00 25.36 ? 154 LEU A CG 1 ATOM 800 C CD1 . LEU A 1 156 ? 179.549 69.145 22.894 1.00 25.89 ? 154 LEU A CD1 1 ATOM 801 C CD2 . LEU A 1 156 ? 179.140 71.241 24.167 1.00 23.87 ? 154 LEU A CD2 1 ATOM 802 N N . LEU A 1 157 ? 180.081 72.799 19.721 1.00 23.94 ? 155 LEU A N 1 ATOM 803 C CA . LEU A 1 157 ? 179.035 73.423 18.906 1.00 23.57 ? 155 LEU A CA 1 ATOM 804 C C . LEU A 1 157 ? 179.112 73.094 17.437 1.00 28.72 ? 155 LEU A C 1 ATOM 805 O O . LEU A 1 157 ? 178.082 73.179 16.768 1.00 31.86 ? 155 LEU A O 1 ATOM 806 C CB . LEU A 1 157 ? 178.912 74.965 19.087 1.00 22.93 ? 155 LEU A CB 1 ATOM 807 C CG . LEU A 1 157 ? 178.993 75.556 20.513 1.00 24.91 ? 155 LEU A CG 1 ATOM 808 C CD1 . LEU A 1 157 ? 179.210 77.065 20.465 1.00 21.84 ? 155 LEU A CD1 1 ATOM 809 C CD2 . LEU A 1 157 ? 177.811 75.102 21.405 1.00 25.53 ? 155 LEU A CD2 1 ATOM 810 N N . ARG A 1 158 ? 180.279 72.741 16.908 1.00 23.94 ? 156 ARG A N 1 ATOM 811 C CA . ARG A 1 158 ? 180.348 72.433 15.473 1.00 24.10 ? 156 ARG A CA 1 ATOM 812 C C . ARG A 1 158 ? 179.575 71.147 15.140 1.00 31.23 ? 156 ARG A C 1 ATOM 813 O O . ARG A 1 158 ? 178.998 71.023 14.048 1.00 31.56 ? 156 ARG A O 1 ATOM 814 C CB . ARG A 1 158 ? 181.788 72.406 14.940 1.00 21.09 ? 156 ARG A CB 1 ATOM 815 C CG . ARG A 1 158 ? 182.659 71.286 15.493 1.00 27.42 ? 156 ARG A CG 1 ATOM 816 C CD . ARG A 1 158 ? 184.011 71.243 14.792 1.00 35.51 ? 156 ARG A CD 1 ATOM 817 N NE . ARG A 1 158 ? 183.899 70.858 13.384 1.00 38.73 ? 156 ARG A NE 1 ATOM 818 C CZ . ARG A 1 158 ? 183.831 69.604 12.938 1.00 56.07 ? 156 ARG A CZ 1 ATOM 819 N NH1 . ARG A 1 158 ? 183.857 68.579 13.792 1.00 31.63 ? 156 ARG A NH1 1 ATOM 820 N NH2 . ARG A 1 158 ? 183.734 69.363 11.639 1.00 48.63 ? 156 ARG A NH2 1 ATOM 821 N N . LEU A 1 159 ? 179.513 70.231 16.124 1.00 28.25 ? 157 LEU A N 1 ATOM 822 C CA . LEU A 1 159 ? 178.787 68.969 16.024 1.00 28.20 ? 157 LEU A CA 1 ATOM 823 C C . LEU A 1 159 ? 177.265 69.184 15.836 1.00 32.89 ? 157 LEU A C 1 ATOM 824 O O . LEU A 1 159 ? 176.584 68.339 15.257 1.00 31.76 ? 157 LEU A O 1 ATOM 825 C CB . LEU A 1 159 ? 179.071 68.112 17.268 1.00 27.37 ? 157 LEU A CB 1 ATOM 826 C CG . LEU A 1 159 ? 180.538 67.857 17.590 1.00 30.84 ? 157 LEU A CG 1 ATOM 827 C CD1 . LEU A 1 159 ? 180.676 66.993 18.843 1.00 31.28 ? 157 LEU A CD1 1 ATOM 828 C CD2 . LEU A 1 159 ? 181.270 67.192 16.411 1.00 30.46 ? 157 LEU A CD2 1 ATOM 829 N N . PHE A 1 160 ? 176.768 70.341 16.287 1.00 30.04 ? 158 PHE A N 1 ATOM 830 C CA . PHE A 1 160 ? 175.366 70.740 16.244 1.00 29.84 ? 158 PHE A CA 1 ATOM 831 C C . PHE A 1 160 ? 175.111 71.946 15.330 1.00 33.59 ? 158 PHE A C 1 ATOM 832 O O . PHE A 1 160 ? 173.993 72.455 15.266 1.00 33.62 ? 158 PHE A O 1 ATOM 833 C CB . PHE A 1 160 ? 174.887 70.980 17.677 1.00 31.53 ? 158 PHE A CB 1 ATOM 834 C CG . PHE A 1 160 ? 175.020 69.721 18.497 1.00 33.26 ? 158 PHE A CG 1 ATOM 835 C CD1 . PHE A 1 160 ? 174.031 68.736 18.456 1.00 36.82 ? 158 PHE A CD1 1 ATOM 836 C CD2 . PHE A 1 160 ? 176.183 69.462 19.217 1.00 34.79 ? 158 PHE A CD2 1 ATOM 837 C CE1 . PHE A 1 160 ? 174.175 67.538 19.171 1.00 37.34 ? 158 PHE A CE1 1 ATOM 838 C CE2 . PHE A 1 160 ? 176.329 68.265 19.936 1.00 37.89 ? 158 PHE A CE2 1 ATOM 839 C CZ . PHE A 1 160 ? 175.321 67.313 19.912 1.00 36.02 ? 158 PHE A CZ 1 ATOM 840 N N . GLN A 1 161 ? 176.120 72.309 14.531 1.00 29.30 ? 159 GLN A N 1 ATOM 841 C CA . GLN A 1 161 ? 176.110 73.447 13.609 1.00 29.51 ? 159 GLN A CA 1 ATOM 842 C C . GLN A 1 161 ? 175.651 74.733 14.308 1.00 29.88 ? 159 GLN A C 1 ATOM 843 O O . GLN A 1 161 ? 174.752 75.396 13.817 1.00 30.45 ? 159 GLN A O 1 ATOM 844 C CB . GLN A 1 161 ? 175.350 73.216 12.256 1.00 31.38 ? 159 GLN A CB 1 ATOM 845 C CG . GLN A 1 161 ? 174.712 71.847 12.000 1.00 46.24 ? 159 GLN A CG 1 ATOM 846 C CD . GLN A 1 161 ? 175.735 70.815 11.650 1.00 56.84 ? 159 GLN A CD 1 ATOM 847 O OE1 . GLN A 1 161 ? 176.408 70.913 10.618 1.00 62.23 ? 159 GLN A OE1 1 ATOM 848 N NE2 . GLN A 1 161 ? 175.876 69.806 12.507 1.00 25.21 ? 159 GLN A NE2 1 ATOM 849 N N . ILE A 1 162 ? 176.246 75.056 15.460 1.00 22.78 ? 160 ILE A N 1 ATOM 850 C CA . ILE A 1 162 ? 175.893 76.273 16.195 1.00 21.73 ? 160 ILE A CA 1 ATOM 851 C C . ILE A 1 162 ? 176.993 77.345 16.016 1.00 24.89 ? 160 ILE A C 1 ATOM 852 O O . ILE A 1 162 ? 178.091 77.181 16.564 1.00 21.97 ? 160 ILE A O 1 ATOM 853 C CB . ILE A 1 162 ? 175.511 76.041 17.718 1.00 23.00 ? 160 ILE A CB 1 ATOM 854 C CG1 . ILE A 1 162 ? 174.315 75.044 17.854 1.00 23.80 ? 160 ILE A CG1 1 ATOM 855 C CG2 . ILE A 1 162 ? 175.225 77.371 18.440 1.00 16.43 ? 160 ILE A CG2 1 ATOM 856 C CD1 . ILE A 1 162 ? 174.157 74.303 19.216 1.00 25.98 ? 160 ILE A CD1 1 ATOM 857 N N . PRO A 1 163 ? 176.683 78.450 15.283 1.00 22.34 ? 161 PRO A N 1 ATOM 858 C CA . PRO A 1 163 ? 177.640 79.559 15.161 1.00 22.03 ? 161 PRO A CA 1 ATOM 859 C C . PRO A 1 163 ? 178.036 80.144 16.519 1.00 25.93 ? 161 PRO A C 1 ATOM 860 O O . PRO A 1 163 ? 177.220 80.258 17.435 1.00 25.31 ? 161 PRO A O 1 ATOM 861 C CB . PRO A 1 163 ? 176.880 80.585 14.320 1.00 23.75 ? 161 PRO A CB 1 ATOM 862 C CG . PRO A 1 163 ? 175.883 79.786 13.572 1.00 28.20 ? 161 PRO A CG 1 ATOM 863 C CD . PRO A 1 163 ? 175.428 78.774 14.578 1.00 23.48 ? 161 PRO A CD 1 ATOM 864 N N . GLN A 1 164 ? 179.322 80.479 16.645 1.00 21.23 ? 162 GLN A N 1 ATOM 865 C CA . GLN A 1 164 ? 179.897 80.997 17.861 1.00 19.40 ? 162 GLN A CA 1 ATOM 866 C C . GLN A 1 164 ? 180.678 82.248 17.547 1.00 22.79 ? 162 GLN A C 1 ATOM 867 O O . GLN A 1 164 ? 181.495 82.256 16.611 1.00 21.97 ? 162 GLN A O 1 ATOM 868 C CB . GLN A 1 164 ? 180.814 79.944 18.466 1.00 19.88 ? 162 GLN A CB 1 ATOM 869 C CG . GLN A 1 164 ? 181.387 80.320 19.834 1.00 15.01 ? 162 GLN A CG 1 ATOM 870 C CD . GLN A 1 164 ? 182.437 79.330 20.226 1.00 31.20 ? 162 GLN A CD 1 ATOM 871 O OE1 . GLN A 1 164 ? 182.568 78.259 19.632 1.00 33.66 ? 162 GLN A OE1 1 ATOM 872 N NE2 . GLN A 1 164 ? 183.231 79.668 21.210 1.00 16.83 ? 162 GLN A NE2 1 ATOM 873 N N . ILE A 1 165 ? 180.427 83.312 18.343 1.00 18.06 ? 163 ILE A N 1 ATOM 874 C CA . ILE A 1 165 ? 181.129 84.583 18.225 1.00 16.71 ? 163 ILE A CA 1 ATOM 875 C C . ILE A 1 165 ? 181.769 84.944 19.563 1.00 21.22 ? 163 ILE A C 1 ATOM 876 O O . ILE A 1 165 ? 181.065 85.333 20.483 1.00 21.05 ? 163 ILE A O 1 ATOM 877 C CB . ILE A 1 165 ? 180.275 85.727 17.603 1.00 19.18 ? 163 ILE A CB 1 ATOM 878 C CG1 . ILE A 1 165 ? 179.806 85.341 16.190 1.00 19.58 ? 163 ILE A CG1 1 ATOM 879 C CG2 . ILE A 1 165 ? 181.086 87.012 17.519 1.00 20.84 ? 163 ILE A CG2 1 ATOM 880 C CD1 . ILE A 1 165 ? 178.577 86.131 15.689 1.00 27.02 ? 163 ILE A CD1 1 ATOM 881 N N . SER A 1 166 ? 183.101 84.782 19.683 1.00 19.05 ? 164 SER A N 1 ATOM 882 C CA . SER A 1 166 ? 183.815 85.180 20.902 1.00 19.58 ? 164 SER A CA 1 ATOM 883 C C . SER A 1 166 ? 184.123 86.693 20.872 1.00 22.38 ? 164 SER A C 1 ATOM 884 O O . SER A 1 166 ? 184.351 87.276 19.816 1.00 20.72 ? 164 SER A O 1 ATOM 885 C CB . SER A 1 166 ? 185.112 84.403 21.090 1.00 22.58 ? 164 SER A CB 1 ATOM 886 O OG . SER A 1 166 ? 185.914 85.028 22.079 1.00 28.37 ? 164 SER A OG 1 ATOM 887 N N . TYR A 1 167 ? 184.192 87.292 22.051 1.00 18.40 ? 165 TYR A N 1 ATOM 888 C CA . TYR A 1 167 ? 184.437 88.721 22.201 1.00 17.43 ? 165 TYR A CA 1 ATOM 889 C C . TYR A 1 167 ? 185.861 89.002 22.750 1.00 20.41 ? 165 TYR A C 1 ATOM 890 O O . TYR A 1 167 ? 186.246 90.166 22.852 1.00 18.25 ? 165 TYR A O 1 ATOM 891 C CB . TYR A 1 167 ? 183.338 89.320 23.119 1.00 16.55 ? 165 TYR A CB 1 ATOM 892 C CG . TYR A 1 167 ? 183.149 88.499 24.383 1.00 15.23 ? 165 TYR A CG 1 ATOM 893 C CD1 . TYR A 1 167 ? 184.051 88.595 25.442 1.00 16.60 ? 165 TYR A CD1 1 ATOM 894 C CD2 . TYR A 1 167 ? 182.114 87.575 24.490 1.00 14.21 ? 165 TYR A CD2 1 ATOM 895 C CE1 . TYR A 1 167 ? 183.911 87.811 26.581 1.00 16.35 ? 165 TYR A CE1 1 ATOM 896 C CE2 . TYR A 1 167 ? 181.963 86.792 25.624 1.00 14.31 ? 165 TYR A CE2 1 ATOM 897 C CZ . TYR A 1 167 ? 182.877 86.897 26.659 1.00 24.17 ? 165 TYR A CZ 1 ATOM 898 O OH . TYR A 1 167 ? 182.762 86.094 27.763 1.00 28.40 ? 165 TYR A OH 1 ATOM 899 N N . ALA A 1 168 ? 186.619 87.945 23.154 1.00 17.19 ? 166 ALA A N 1 ATOM 900 C CA . ALA A 1 168 ? 187.945 88.147 23.760 1.00 16.56 ? 166 ALA A CA 1 ATOM 901 C C . ALA A 1 168 ? 188.983 87.060 23.478 1.00 22.26 ? 166 ALA A C 1 ATOM 902 O O . ALA A 1 168 ? 190.141 87.271 23.854 1.00 22.95 ? 166 ALA A O 1 ATOM 903 C CB . ALA A 1 168 ? 187.799 88.337 25.259 1.00 17.32 ? 166 ALA A CB 1 ATOM 904 N N . SER A 1 169 ? 188.591 85.902 22.836 1.00 17.41 ? 167 SER A N 1 ATOM 905 C CA . SER A 1 169 ? 189.497 84.782 22.567 1.00 16.00 ? 167 SER A CA 1 ATOM 906 C C . SER A 1 169 ? 190.385 85.079 21.410 1.00 20.86 ? 167 SER A C 1 ATOM 907 O O . SER A 1 169 ? 189.909 85.178 20.281 1.00 19.79 ? 167 SER A O 1 ATOM 908 C CB . SER A 1 169 ? 188.732 83.485 22.391 1.00 17.98 ? 167 SER A CB 1 ATOM 909 O OG . SER A 1 169 ? 188.158 83.128 23.640 1.00 24.74 ? 167 SER A OG 1 ATOM 910 N N . THR A 1 170 ? 191.691 85.259 21.688 1.00 17.90 ? 168 THR A N 1 ATOM 911 C CA . THR A 1 170 ? 192.638 85.708 20.660 1.00 17.76 ? 168 THR A CA 1 ATOM 912 C C . THR A 1 170 ? 193.580 84.657 20.120 1.00 21.44 ? 168 THR A C 1 ATOM 913 O O . THR A 1 170 ? 194.328 84.975 19.187 1.00 19.47 ? 168 THR A O 1 ATOM 914 C CB . THR A 1 170 ? 193.442 86.877 21.188 1.00 25.14 ? 168 THR A CB 1 ATOM 915 O OG1 . THR A 1 170 ? 194.043 86.426 22.398 1.00 26.47 ? 168 THR A OG1 1 ATOM 916 C CG2 . THR A 1 170 ? 192.594 88.144 21.440 1.00 21.10 ? 168 THR A CG2 1 ATOM 917 N N . SER A 1 171 ? 193.552 83.407 20.668 1.00 18.72 ? 169 SER A N 1 ATOM 918 C CA . SER A 1 171 ? 194.459 82.365 20.196 1.00 19.21 ? 169 SER A CA 1 ATOM 919 C C . SER A 1 171 ? 194.309 82.189 18.706 1.00 25.93 ? 169 SER A C 1 ATOM 920 O O . SER A 1 171 ? 193.185 82.096 18.214 1.00 26.79 ? 169 SER A O 1 ATOM 921 C CB . SER A 1 171 ? 194.220 81.036 20.908 1.00 21.99 ? 169 SER A CB 1 ATOM 922 O OG . SER A 1 171 ? 194.775 79.923 20.218 1.00 24.40 ? 169 SER A OG 1 ATOM 923 N N . ALA A 1 172 ? 195.444 82.128 17.999 1.00 22.64 ? 170 ALA A N 1 ATOM 924 C CA . ALA A 1 172 ? 195.522 81.926 16.563 1.00 22.78 ? 170 ALA A CA 1 ATOM 925 C C . ALA A 1 172 ? 195.007 80.548 16.110 1.00 28.15 ? 170 ALA A C 1 ATOM 926 O O . ALA A 1 172 ? 194.638 80.405 14.945 1.00 30.23 ? 170 ALA A O 1 ATOM 927 C CB . ALA A 1 172 ? 196.940 82.131 16.095 1.00 23.41 ? 170 ALA A CB 1 ATOM 928 N N . LYS A 1 173 ? 194.938 79.547 17.014 1.00 23.15 ? 171 LYS A N 1 ATOM 929 C CA . LYS A 1 173 ? 194.451 78.198 16.662 1.00 21.36 ? 171 LYS A CA 1 ATOM 930 C C . LYS A 1 173 ? 193.027 78.299 16.138 1.00 22.17 ? 171 LYS A C 1 ATOM 931 O O . LYS A 1 173 ? 192.646 77.563 15.231 1.00 21.68 ? 171 LYS A O 1 ATOM 932 C CB . LYS A 1 173 ? 194.475 77.242 17.880 1.00 23.67 ? 171 LYS A CB 1 ATOM 933 C CG . LYS A 1 173 ? 195.820 77.113 18.581 1.00 39.04 ? 171 LYS A CG 1 ATOM 934 C CD . LYS A 1 173 ? 196.695 75.980 18.032 1.00 56.30 ? 171 LYS A CD 1 ATOM 935 C CE . LYS A 1 173 ? 196.659 74.737 18.905 1.00 77.81 ? 171 LYS A CE 1 ATOM 936 N NZ . LYS A 1 173 ? 197.479 74.864 20.145 1.00 82.03 ? 171 LYS A NZ 1 ATOM 937 N N . LEU A 1 174 ? 192.270 79.270 16.673 1.00 16.20 ? 172 LEU A N 1 ATOM 938 C CA . LEU A 1 174 ? 190.894 79.516 16.330 1.00 15.79 ? 172 LEU A CA 1 ATOM 939 C C . LEU A 1 174 ? 190.687 80.015 14.881 1.00 21.22 ? 172 LEU A C 1 ATOM 940 O O . LEU A 1 174 ? 189.570 79.951 14.364 1.00 20.17 ? 172 LEU A O 1 ATOM 941 C CB . LEU A 1 174 ? 190.287 80.453 17.369 1.00 16.01 ? 172 LEU A CB 1 ATOM 942 C CG . LEU A 1 174 ? 189.877 79.745 18.667 1.00 20.09 ? 172 LEU A CG 1 ATOM 943 C CD1 . LEU A 1 174 ? 189.818 80.695 19.838 1.00 18.83 ? 172 LEU A CD1 1 ATOM 944 C CD2 . LEU A 1 174 ? 188.585 78.990 18.483 1.00 23.12 ? 172 LEU A CD2 1 ATOM 945 N N . SER A 1 175 ? 191.761 80.442 14.206 1.00 19.05 ? 173 SER A N 1 ATOM 946 C CA . SER A 1 175 ? 191.668 80.867 12.812 1.00 18.84 ? 173 SER A CA 1 ATOM 947 C C . SER A 1 175 ? 191.523 79.687 11.862 1.00 24.45 ? 173 SER A C 1 ATOM 948 O O . SER A 1 175 ? 191.172 79.900 10.708 1.00 26.28 ? 173 SER A O 1 ATOM 949 C CB . SER A 1 175 ? 192.882 81.695 12.422 1.00 19.47 ? 173 SER A CB 1 ATOM 950 O OG . SER A 1 175 ? 192.799 82.950 13.063 1.00 25.74 ? 173 SER A OG 1 ATOM 951 N N . ASP A 1 176 ? 191.812 78.450 12.321 1.00 21.01 ? 174 ASP A N 1 ATOM 952 C CA . ASP A 1 176 ? 191.745 77.230 11.500 1.00 19.55 ? 174 ASP A CA 1 ATOM 953 C C . ASP A 1 176 ? 190.313 76.753 11.288 1.00 24.12 ? 174 ASP A C 1 ATOM 954 O O . ASP A 1 176 ? 189.735 76.106 12.159 1.00 25.29 ? 174 ASP A O 1 ATOM 955 C CB . ASP A 1 176 ? 192.641 76.140 12.083 1.00 20.74 ? 174 ASP A CB 1 ATOM 956 C CG . ASP A 1 176 ? 192.854 74.899 11.242 1.00 36.85 ? 174 ASP A CG 1 ATOM 957 O OD1 . ASP A 1 176 ? 192.221 74.791 10.160 1.00 39.18 ? 174 ASP A OD1 1 ATOM 958 O OD2 . ASP A 1 176 ? 193.709 74.059 11.629 1.00 43.24 ? 174 ASP A OD2 1 ATOM 959 N N . LYS A 1 177 ? 189.753 77.061 10.111 1.00 21.18 ? 175 LYS A N 1 ATOM 960 C CA . LYS A 1 177 ? 188.375 76.708 9.742 1.00 21.35 ? 175 LYS A CA 1 ATOM 961 C C . LYS A 1 177 ? 188.197 75.222 9.395 1.00 26.99 ? 175 LYS A C 1 ATOM 962 O O . LYS A 1 177 ? 187.074 74.788 9.141 1.00 25.55 ? 175 LYS A O 1 ATOM 963 C CB . LYS A 1 177 ? 187.810 77.635 8.637 1.00 21.23 ? 175 LYS A CB 1 ATOM 964 C CG . LYS A 1 177 ? 187.817 79.132 8.996 1.00 26.86 ? 175 LYS A CG 1 ATOM 965 C CD . LYS A 1 177 ? 187.045 79.498 10.307 1.00 34.71 ? 175 LYS A CD 1 ATOM 966 C CE . LYS A 1 177 ? 187.937 79.625 11.529 1.00 24.60 ? 175 LYS A CE 1 ATOM 967 N NZ . LYS A 1 177 ? 187.235 80.175 12.721 1.00 25.53 ? 175 LYS A NZ 1 ATOM 968 N N . SER A 1 178 ? 189.280 74.438 9.424 1.00 26.60 ? 176 SER A N 1 ATOM 969 C CA . SER A 1 178 ? 189.150 72.993 9.224 1.00 27.94 ? 176 SER A CA 1 ATOM 970 C C . SER A 1 178 ? 188.743 72.394 10.580 1.00 34.51 ? 176 SER A C 1 ATOM 971 O O . SER A 1 178 ? 187.971 71.437 10.619 1.00 37.72 ? 176 SER A O 1 ATOM 972 C CB . SER A 1 178 ? 190.460 72.382 8.743 1.00 30.51 ? 176 SER A CB 1 ATOM 973 O OG . SER A 1 178 ? 191.414 72.274 9.787 1.00 40.57 ? 176 SER A OG 1 ATOM 974 N N . ARG A 1 179 ? 189.230 73.016 11.680 1.00 27.45 ? 177 ARG A N 1 ATOM 975 C CA . ARG A 1 179 ? 188.998 72.635 13.050 1.00 26.02 ? 177 ARG A CA 1 ATOM 976 C C . ARG A 1 179 ? 187.822 73.380 13.708 1.00 29.53 ? 177 ARG A C 1 ATOM 977 O O . ARG A 1 179 ? 187.061 72.746 14.443 1.00 30.70 ? 177 ARG A O 1 ATOM 978 C CB . ARG A 1 179 ? 190.319 72.790 13.862 1.00 27.59 ? 177 ARG A CB 1 ATOM 979 C CG . ARG A 1 179 ? 190.963 71.440 14.191 1.00 43.50 ? 177 ARG A CG 1 ATOM 980 C CD . ARG A 1 179 ? 192.153 71.396 15.161 1.00 55.94 ? 177 ARG A CD 1 ATOM 981 N NE . ARG A 1 179 ? 191.841 71.604 16.590 1.00 74.38 ? 177 ARG A NE 1 ATOM 982 C CZ . ARG A 1 179 ? 191.089 70.819 17.379 1.00 75.61 ? 177 ARG A CZ 1 ATOM 983 N NH1 . ARG A 1 179 ? 190.458 69.759 16.870 1.00 45.99 ? 177 ARG A NH1 1 ATOM 984 N NH2 . ARG A 1 179 ? 190.921 71.121 18.672 1.00 42.08 ? 177 ARG A NH2 1 ATOM 985 N N . TYR A 1 180 ? 187.687 74.724 13.494 1.00 24.43 ? 178 TYR A N 1 ATOM 986 C CA . TYR A 1 180 ? 186.666 75.585 14.134 1.00 22.86 ? 178 TYR A CA 1 ATOM 987 C C . TYR A 1 180 ? 185.833 76.277 13.080 1.00 29.30 ? 178 TYR A C 1 ATOM 988 O O . TYR A 1 180 ? 185.845 77.505 12.959 1.00 31.92 ? 178 TYR A O 1 ATOM 989 C CB . TYR A 1 180 ? 187.331 76.621 15.080 1.00 21.42 ? 178 TYR A CB 1 ATOM 990 C CG . TYR A 1 180 ? 188.367 75.971 15.950 1.00 21.92 ? 178 TYR A CG 1 ATOM 991 C CD1 . TYR A 1 180 ? 187.999 75.096 16.972 1.00 22.74 ? 178 TYR A CD1 1 ATOM 992 C CD2 . TYR A 1 180 ? 189.720 76.090 15.654 1.00 23.42 ? 178 TYR A CD2 1 ATOM 993 C CE1 . TYR A 1 180 ? 188.953 74.374 17.685 1.00 22.42 ? 178 TYR A CE1 1 ATOM 994 C CE2 . TYR A 1 180 ? 190.685 75.391 16.380 1.00 24.00 ? 178 TYR A CE2 1 ATOM 995 C CZ . TYR A 1 180 ? 190.298 74.526 17.383 1.00 30.75 ? 178 TYR A CZ 1 ATOM 996 O OH . TYR A 1 180 ? 191.280 73.887 18.107 1.00 36.87 ? 178 TYR A OH 1 ATOM 997 N N . ASP A 1 181 ? 185.090 75.489 12.337 1.00 23.76 ? 179 ASP A N 1 ATOM 998 C CA . ASP A 1 181 ? 184.339 75.959 11.185 1.00 23.28 ? 179 ASP A CA 1 ATOM 999 C C . ASP A 1 181 ? 183.131 76.811 11.525 1.00 25.19 ? 179 ASP A C 1 ATOM 1000 O O . ASP A 1 181 ? 182.723 77.573 10.659 1.00 25.30 ? 179 ASP A O 1 ATOM 1001 C CB . ASP A 1 181 ? 183.970 74.813 10.216 1.00 25.02 ? 179 ASP A CB 1 ATOM 1002 C CG . ASP A 1 181 ? 183.496 73.493 10.801 1.00 43.28 ? 179 ASP A CG 1 ATOM 1003 O OD1 . ASP A 1 181 ? 183.879 73.175 11.942 1.00 44.50 ? 179 ASP A OD1 1 ATOM 1004 O OD2 . ASP A 1 181 ? 182.793 72.744 10.085 1.00 54.07 ? 179 ASP A OD2 1 ATOM 1005 N N . TYR A 1 182 ? 182.621 76.773 12.773 1.00 20.20 ? 180 TYR A N 1 ATOM 1006 C CA . TYR A 1 182 ? 181.443 77.580 13.188 1.00 19.04 ? 180 TYR A CA 1 ATOM 1007 C C . TYR A 1 182 ? 181.819 78.743 14.106 1.00 23.26 ? 180 TYR A C 1 ATOM 1008 O O . TYR A 1 182 ? 180.945 79.313 14.755 1.00 22.71 ? 180 TYR A O 1 ATOM 1009 C CB . TYR A 1 182 ? 180.388 76.676 13.866 1.00 19.80 ? 180 TYR A CB 1 ATOM 1010 C CG . TYR A 1 182 ? 179.635 75.870 12.843 1.00 22.85 ? 180 TYR A CG 1 ATOM 1011 C CD1 . TYR A 1 182 ? 180.157 74.673 12.347 1.00 24.05 ? 180 TYR A CD1 1 ATOM 1012 C CD2 . TYR A 1 182 ? 178.486 76.372 12.247 1.00 24.89 ? 180 TYR A CD2 1 ATOM 1013 C CE1 . TYR A 1 182 ? 179.541 73.992 11.306 1.00 22.40 ? 180 TYR A CE1 1 ATOM 1014 C CE2 . TYR A 1 182 ? 177.862 75.698 11.201 1.00 26.45 ? 180 TYR A CE2 1 ATOM 1015 C CZ . TYR A 1 182 ? 178.387 74.505 10.742 1.00 32.49 ? 180 TYR A CZ 1 ATOM 1016 O OH . TYR A 1 182 ? 177.750 73.856 9.714 1.00 36.02 ? 180 TYR A OH 1 ATOM 1017 N N . PHE A 1 183 ? 183.126 79.079 14.180 1.00 18.95 ? 181 PHE A N 1 ATOM 1018 C CA . PHE A 1 183 ? 183.628 80.104 15.073 1.00 17.41 ? 181 PHE A CA 1 ATOM 1019 C C . PHE A 1 183 ? 184.062 81.328 14.353 1.00 23.00 ? 181 PHE A C 1 ATOM 1020 O O . PHE A 1 183 ? 184.730 81.233 13.328 1.00 24.98 ? 181 PHE A O 1 ATOM 1021 C CB . PHE A 1 183 ? 184.782 79.543 15.922 1.00 18.03 ? 181 PHE A CB 1 ATOM 1022 C CG . PHE A 1 183 ? 185.429 80.521 16.871 1.00 17.25 ? 181 PHE A CG 1 ATOM 1023 C CD1 . PHE A 1 183 ? 184.945 80.686 18.156 1.00 18.42 ? 181 PHE A CD1 1 ATOM 1024 C CD2 . PHE A 1 183 ? 186.525 81.289 16.469 1.00 18.45 ? 181 PHE A CD2 1 ATOM 1025 C CE1 . PHE A 1 183 ? 185.555 81.584 19.039 1.00 18.54 ? 181 PHE A CE1 1 ATOM 1026 C CE2 . PHE A 1 183 ? 187.112 82.214 17.332 1.00 19.86 ? 181 PHE A CE2 1 ATOM 1027 C CZ . PHE A 1 183 ? 186.632 82.343 18.618 1.00 17.82 ? 181 PHE A CZ 1 ATOM 1028 N N . ALA A 1 184 ? 183.698 82.474 14.897 1.00 17.27 ? 182 ALA A N 1 ATOM 1029 C CA . ALA A 1 184 ? 184.145 83.773 14.486 1.00 16.47 ? 182 ALA A CA 1 ATOM 1030 C C . ALA A 1 184 ? 184.410 84.609 15.715 1.00 23.92 ? 182 ALA A C 1 ATOM 1031 O O . ALA A 1 184 ? 184.015 84.257 16.761 1.00 24.69 ? 182 ALA A O 1 ATOM 1032 C CB . ALA A 1 184 ? 183.105 84.431 13.636 1.00 17.06 ? 182 ALA A CB 1 ATOM 1033 N N . ARG A 1 185 ? 185.076 85.730 15.575 1.00 20.36 ? 183 ARG A N 1 ATOM 1034 C CA . ARG A 1 185 ? 185.409 86.565 16.712 1.00 19.64 ? 183 ARG A CA 1 ATOM 1035 C C . ARG A 1 185 ? 185.522 88.016 16.362 1.00 23.80 ? 183 ARG A C 1 ATOM 1036 O O . ARG A 1 185 ? 185.779 88.330 15.264 1.00 23.18 ? 183 ARG A O 1 ATOM 1037 C CB . ARG A 1 185 ? 186.680 86.075 17.362 1.00 17.72 ? 183 ARG A CB 1 ATOM 1038 C CG . ARG A 1 185 ? 187.790 85.906 16.396 1.00 18.05 ? 183 ARG A CG 1 ATOM 1039 C CD . ARG A 1 185 ? 189.036 85.703 17.135 1.00 12.50 ? 183 ARG A CD 1 ATOM 1040 N NE . ARG A 1 185 ? 190.013 85.022 16.343 1.00 15.86 ? 183 ARG A NE 1 ATOM 1041 C CZ . ARG A 1 185 ? 190.889 84.199 16.839 1.00 20.64 ? 183 ARG A CZ 1 ATOM 1042 N NH1 . ARG A 1 185 ? 190.891 83.947 18.087 1.00 5.23 ? 183 ARG A NH1 1 ATOM 1043 N NH2 . ARG A 1 185 ? 191.739 83.629 16.090 1.00 14.97 ? 183 ARG A NH2 1 ATOM 1044 N N . THR A 1 186 ? 185.297 88.899 17.310 1.00 18.73 ? 184 THR A N 1 ATOM 1045 C CA . THR A 1 186 ? 185.326 90.314 17.040 1.00 18.13 ? 184 THR A CA 1 ATOM 1046 C C . THR A 1 186 ? 186.639 90.921 17.432 1.00 22.87 ? 184 THR A C 1 ATOM 1047 O O . THR A 1 186 ? 186.820 92.087 17.364 1.00 24.23 ? 184 THR A O 1 ATOM 1048 C CB . THR A 1 186 ? 184.154 91.092 17.658 1.00 25.64 ? 184 THR A CB 1 ATOM 1049 O OG1 . THR A 1 186 ? 184.007 90.769 19.015 1.00 32.05 ? 184 THR A OG1 1 ATOM 1050 C CG2 . THR A 1 186 ? 182.924 90.796 17.003 1.00 23.42 ? 184 THR A CG2 1 ATOM 1051 N N . VAL A 1 187 ? 187.562 90.073 17.827 1.00 19.29 ? 185 VAL A N 1 ATOM 1052 C CA . VAL A 1 187 ? 188.889 90.448 18.220 1.00 18.04 ? 185 VAL A CA 1 ATOM 1053 C C . VAL A 1 187 ? 189.804 89.840 17.207 1.00 24.17 ? 185 VAL A C 1 ATOM 1054 O O . VAL A 1 187 ? 189.398 88.948 16.525 1.00 23.32 ? 185 VAL A O 1 ATOM 1055 C CB . VAL A 1 187 ? 189.243 89.952 19.638 1.00 18.83 ? 185 VAL A CB 1 ATOM 1056 C CG1 . VAL A 1 187 ? 188.684 90.873 20.682 1.00 16.88 ? 185 VAL A CG1 1 ATOM 1057 C CG2 . VAL A 1 187 ? 188.839 88.525 19.862 1.00 17.58 ? 185 VAL A CG2 1 ATOM 1058 N N . PRO A 1 188 ? 191.073 90.423 17.071 1.00 22.02 ? 186 PRO A N 1 ATOM 1059 C CA . PRO A 1 188 ? 191.951 89.695 16.147 1.00 21.74 ? 186 PRO A CA 1 ATOM 1060 C C . PRO A 1 188 ? 192.821 88.577 16.678 1.00 24.22 ? 186 PRO A C 1 ATOM 1061 O O . PRO A 1 188 ? 192.982 88.414 17.853 1.00 23.89 ? 186 PRO A O 1 ATOM 1062 C CB . PRO A 1 188 ? 192.783 90.771 15.529 1.00 23.77 ? 186 PRO A CB 1 ATOM 1063 C CG . PRO A 1 188 ? 193.028 91.682 16.598 1.00 28.40 ? 186 PRO A CG 1 ATOM 1064 C CD . PRO A 1 188 ? 191.832 91.705 17.449 1.00 23.91 ? 186 PRO A CD 1 ATOM 1065 N N . PRO A 1 189 ? 193.391 87.775 15.681 1.00 20.87 ? 187 PRO A N 1 ATOM 1066 C CA . PRO A 1 189 ? 194.314 86.763 16.186 1.00 20.31 ? 187 PRO A CA 1 ATOM 1067 C C . PRO A 1 189 ? 195.644 87.271 16.719 1.00 22.96 ? 187 PRO A C 1 ATOM 1068 O O . PRO A 1 189 ? 196.091 88.329 16.433 1.00 19.70 ? 187 PRO A O 1 ATOM 1069 C CB . PRO A 1 189 ? 194.523 85.869 14.998 1.00 22.31 ? 187 PRO A CB 1 ATOM 1070 C CG . PRO A 1 189 ? 194.507 86.775 13.876 1.00 25.59 ? 187 PRO A CG 1 ATOM 1071 C CD . PRO A 1 189 ? 193.308 87.544 14.159 1.00 21.86 ? 187 PRO A CD 1 ATOM 1072 N N . ASP A 1 190 ? 196.249 86.447 17.541 1.00 22.22 ? 188 ASP A N 1 ATOM 1073 C CA . ASP A 1 190 ? 197.386 86.838 18.311 1.00 24.27 ? 188 ASP A CA 1 ATOM 1074 C C . ASP A 1 190 ? 198.654 86.821 17.544 1.00 33.57 ? 188 ASP A C 1 ATOM 1075 O O . ASP A 1 190 ? 199.673 87.226 18.021 1.00 34.25 ? 188 ASP A O 1 ATOM 1076 C CB . ASP A 1 190 ? 197.530 85.955 19.501 1.00 27.00 ? 188 ASP A CB 1 ATOM 1077 C CG . ASP A 1 190 ? 196.929 86.531 20.711 1.00 45.33 ? 188 ASP A CG 1 ATOM 1078 O OD1 . ASP A 1 190 ? 196.651 87.716 20.755 1.00 46.78 ? 188 ASP A OD1 1 ATOM 1079 O OD2 . ASP A 1 190 ? 196.742 85.772 21.646 1.00 53.28 ? 188 ASP A OD2 1 ATOM 1080 N N . PHE A 1 191 ? 198.555 86.317 16.341 1.00 32.37 ? 189 PHE A N 1 ATOM 1081 C CA . PHE A 1 191 ? 199.342 86.648 15.203 1.00 33.06 ? 189 PHE A CA 1 ATOM 1082 C C . PHE A 1 191 ? 199.894 88.036 15.282 1.00 36.32 ? 189 PHE A C 1 ATOM 1083 O O . PHE A 1 191 ? 201.057 88.249 15.135 1.00 38.35 ? 189 PHE A O 1 ATOM 1084 C CB . PHE A 1 191 ? 198.352 86.638 14.073 1.00 36.17 ? 189 PHE A CB 1 ATOM 1085 C CG . PHE A 1 191 ? 198.909 86.318 12.744 1.00 40.58 ? 189 PHE A CG 1 ATOM 1086 C CD1 . PHE A 1 191 ? 199.459 85.095 12.490 1.00 44.14 ? 189 PHE A CD1 1 ATOM 1087 C CD2 . PHE A 1 191 ? 198.790 87.220 11.709 1.00 44.67 ? 189 PHE A CD2 1 ATOM 1088 C CE1 . PHE A 1 191 ? 199.926 84.791 11.238 1.00 45.22 ? 189 PHE A CE1 1 ATOM 1089 C CE2 . PHE A 1 191 ? 199.253 86.921 10.456 1.00 47.47 ? 189 PHE A CE2 1 ATOM 1090 C CZ . PHE A 1 191 ? 199.830 85.706 10.228 1.00 45.46 ? 189 PHE A CZ 1 ATOM 1091 N N . PHE A 1 192 ? 199.024 88.995 15.478 1.00 29.20 ? 190 PHE A N 1 ATOM 1092 C CA . PHE A 1 192 ? 199.399 90.374 15.400 1.00 28.38 ? 190 PHE A CA 1 ATOM 1093 C C . PHE A 1 192 ? 199.891 90.916 16.703 1.00 29.08 ? 190 PHE A C 1 ATOM 1094 O O . PHE A 1 192 ? 200.608 91.846 16.711 1.00 26.78 ? 190 PHE A O 1 ATOM 1095 C CB . PHE A 1 192 ? 198.231 91.226 14.938 1.00 29.45 ? 190 PHE A CB 1 ATOM 1096 C CG . PHE A 1 192 ? 197.716 90.880 13.602 1.00 30.34 ? 190 PHE A CG 1 ATOM 1097 C CD1 . PHE A 1 192 ? 198.382 91.246 12.483 1.00 32.08 ? 190 PHE A CD1 1 ATOM 1098 C CD2 . PHE A 1 192 ? 196.553 90.202 13.470 1.00 33.33 ? 190 PHE A CD2 1 ATOM 1099 C CE1 . PHE A 1 192 ? 197.901 90.937 11.251 1.00 32.94 ? 190 PHE A CE1 1 ATOM 1100 C CE2 . PHE A 1 192 ? 196.065 89.885 12.245 1.00 36.23 ? 190 PHE A CE2 1 ATOM 1101 C CZ . PHE A 1 192 ? 196.743 90.257 11.133 1.00 33.70 ? 190 PHE A CZ 1 ATOM 1102 N N . GLN A 1 193 ? 199.465 90.339 17.798 1.00 24.49 ? 191 GLN A N 1 ATOM 1103 C CA . GLN A 1 193 ? 199.862 90.802 19.087 1.00 23.53 ? 191 GLN A CA 1 ATOM 1104 C C . GLN A 1 193 ? 201.298 90.455 19.319 1.00 28.82 ? 191 GLN A C 1 ATOM 1105 O O . GLN A 1 193 ? 202.038 91.193 19.864 1.00 26.99 ? 191 GLN A O 1 ATOM 1106 C CB . GLN A 1 193 ? 198.997 90.152 20.137 1.00 24.68 ? 191 GLN A CB 1 ATOM 1107 C CG . GLN A 1 193 ? 198.586 91.121 21.193 1.00 31.61 ? 191 GLN A CG 1 ATOM 1108 C CD . GLN A 1 193 ? 198.188 90.514 22.491 1.00 41.04 ? 191 GLN A CD 1 ATOM 1109 O OE1 . GLN A 1 193 ? 198.726 90.849 23.506 1.00 40.95 ? 191 GLN A OE1 1 ATOM 1110 N NE2 . GLN A 1 193 ? 197.196 89.694 22.473 1.00 24.61 ? 191 GLN A NE2 1 ATOM 1111 N N . ALA A 1 194 ? 201.664 89.272 18.894 1.00 27.33 ? 192 ALA A N 1 ATOM 1112 C CA . ALA A 1 194 ? 202.998 88.749 18.976 1.00 27.28 ? 192 ALA A CA 1 ATOM 1113 C C . ALA A 1 194 ? 204.006 89.589 18.229 1.00 32.52 ? 192 ALA A C 1 ATOM 1114 O O . ALA A 1 194 ? 205.066 89.848 18.702 1.00 32.21 ? 192 ALA A O 1 ATOM 1115 C CB . ALA A 1 194 ? 202.972 87.378 18.400 1.00 28.04 ? 192 ALA A CB 1 ATOM 1116 N N . LYS A 1 195 ? 203.639 90.000 17.042 1.00 30.71 ? 193 LYS A N 1 ATOM 1117 C CA . LYS A 1 195 ? 204.458 90.791 16.191 1.00 31.05 ? 193 LYS A CA 1 ATOM 1118 C C . LYS A 1 195 ? 204.692 92.172 16.731 1.00 36.43 ? 193 LYS A C 1 ATOM 1119 O O . LYS A 1 195 ? 205.739 92.725 16.575 1.00 38.12 ? 193 LYS A O 1 ATOM 1120 C CB . LYS A 1 195 ? 203.744 90.890 14.876 1.00 32.71 ? 193 LYS A CB 1 ATOM 1121 C CG . LYS A 1 195 ? 204.608 91.329 13.747 1.00 45.58 ? 193 LYS A CG 1 ATOM 1122 C CD . LYS A 1 195 ? 203.867 91.122 12.462 1.00 61.37 ? 193 LYS A CD 1 ATOM 1123 C CE . LYS A 1 195 ? 204.500 91.914 11.327 1.00 74.16 ? 193 LYS A CE 1 ATOM 1124 N NZ . LYS A 1 195 ? 205.803 91.403 10.825 1.00 78.23 ? 193 LYS A NZ 1 ATOM 1125 N N . ALA A 1 196 ? 203.687 92.718 17.369 1.00 30.55 ? 194 ALA A N 1 ATOM 1126 C CA . ALA A 1 196 ? 203.743 93.999 17.978 1.00 29.45 ? 194 ALA A CA 1 ATOM 1127 C C . ALA A 1 196 ? 204.645 94.004 19.176 1.00 34.53 ? 194 ALA A C 1 ATOM 1128 O O . ALA A 1 196 ? 205.385 94.930 19.404 1.00 34.52 ? 194 ALA A O 1 ATOM 1129 C CB . ALA A 1 196 ? 202.365 94.363 18.393 1.00 29.72 ? 194 ALA A CB 1 ATOM 1130 N N . MET A 1 197 ? 204.563 92.945 19.952 1.00 31.51 ? 195 MET A N 1 ATOM 1131 C CA . MET A 1 197 ? 205.365 92.764 21.138 1.00 30.72 ? 195 MET A CA 1 ATOM 1132 C C . MET A 1 197 ? 206.826 92.665 20.801 1.00 33.26 ? 195 MET A C 1 ATOM 1133 O O . MET A 1 197 ? 207.652 93.089 21.542 1.00 32.90 ? 195 MET A O 1 ATOM 1134 C CB . MET A 1 197 ? 204.916 91.520 21.880 1.00 33.28 ? 195 MET A CB 1 ATOM 1135 C CG . MET A 1 197 ? 203.834 91.736 22.915 1.00 37.11 ? 195 MET A CG 1 ATOM 1136 S SD . MET A 1 197 ? 202.939 90.267 23.407 1.00 41.46 ? 195 MET A SD 1 ATOM 1137 C CE . MET A 1 197 ? 203.864 89.801 24.815 1.00 38.37 ? 195 MET A CE 1 ATOM 1138 N N . ALA A 1 198 ? 207.121 92.114 19.650 1.00 29.95 ? 196 ALA A N 1 ATOM 1139 C CA . ALA A 1 198 ? 208.473 91.947 19.179 1.00 29.70 ? 196 ALA A CA 1 ATOM 1140 C C . ALA A 1 198 ? 209.032 93.201 18.593 1.00 34.78 ? 196 ALA A C 1 ATOM 1141 O O . ALA A 1 198 ? 210.197 93.425 18.629 1.00 33.83 ? 196 ALA A O 1 ATOM 1142 C CB . ALA A 1 198 ? 208.511 90.868 18.143 1.00 30.34 ? 196 ALA A CB 1 ATOM 1143 N N . GLU A 1 199 ? 208.172 94.011 18.028 1.00 32.15 ? 197 GLU A N 1 ATOM 1144 C CA . GLU A 1 199 ? 208.569 95.276 17.520 1.00 32.29 ? 197 GLU A CA 1 ATOM 1145 C C . GLU A 1 199 ? 208.797 96.243 18.638 1.00 37.28 ? 197 GLU A C 1 ATOM 1146 O O . GLU A 1 199 ? 209.491 97.202 18.476 1.00 36.94 ? 197 GLU A O 1 ATOM 1147 C CB . GLU A 1 199 ? 207.503 95.802 16.609 1.00 33.39 ? 197 GLU A CB 1 ATOM 1148 C CG . GLU A 1 199 ? 207.552 95.196 15.253 1.00 43.73 ? 197 GLU A CG 1 ATOM 1149 C CD . GLU A 1 199 ? 206.450 95.676 14.385 1.00 70.77 ? 197 GLU A CD 1 ATOM 1150 O OE1 . GLU A 1 199 ? 206.109 94.970 13.453 1.00 65.80 ? 197 GLU A OE1 1 ATOM 1151 O OE2 . GLU A 1 199 ? 205.928 96.756 14.632 1.00 64.61 ? 197 GLU A OE2 1 ATOM 1152 N N . ILE A 1 200 ? 208.190 95.991 19.776 1.00 33.85 ? 198 ILE A N 1 ATOM 1153 C CA . ILE A 1 200 ? 208.401 96.835 20.923 1.00 33.88 ? 198 ILE A CA 1 ATOM 1154 C C . ILE A 1 200 ? 209.789 96.621 21.473 1.00 36.53 ? 198 ILE A C 1 ATOM 1155 O O . ILE A 1 200 ? 210.482 97.545 21.750 1.00 35.49 ? 198 ILE A O 1 ATOM 1156 C CB . ILE A 1 200 ? 207.330 96.619 21.998 1.00 36.58 ? 198 ILE A CB 1 ATOM 1157 C CG1 . ILE A 1 200 ? 205.980 97.148 21.538 1.00 36.07 ? 198 ILE A CG1 1 ATOM 1158 C CG2 . ILE A 1 200 ? 207.698 97.306 23.292 1.00 35.45 ? 198 ILE A CG2 1 ATOM 1159 C CD1 . ILE A 1 200 ? 204.838 96.677 22.388 1.00 31.27 ? 198 ILE A CD1 1 ATOM 1160 N N . LEU A 1 201 ? 210.197 95.381 21.586 1.00 33.50 ? 199 LEU A N 1 ATOM 1161 C CA . LEU A 1 201 ? 211.511 95.046 22.047 1.00 33.47 ? 199 LEU A CA 1 ATOM 1162 C C . LEU A 1 201 ? 212.578 95.552 21.132 1.00 39.28 ? 199 LEU A C 1 ATOM 1163 O O . LEU A 1 201 ? 213.476 96.196 21.553 1.00 39.59 ? 199 LEU A O 1 ATOM 1164 C CB . LEU A 1 201 ? 211.626 93.550 22.210 1.00 33.16 ? 199 LEU A CB 1 ATOM 1165 C CG . LEU A 1 201 ? 210.598 92.920 23.139 1.00 37.64 ? 199 LEU A CG 1 ATOM 1166 C CD1 . LEU A 1 201 ? 210.826 91.455 23.337 1.00 38.18 ? 199 LEU A CD1 1 ATOM 1167 C CD2 . LEU A 1 201 ? 210.582 93.579 24.471 1.00 36.45 ? 199 LEU A CD2 1 ATOM 1168 N N . ARG A 1 202 ? 212.466 95.230 19.866 1.00 36.44 ? 200 ARG A N 1 ATOM 1169 C CA . ARG A 1 202 ? 213.349 95.708 18.809 1.00 36.35 ? 200 ARG A CA 1 ATOM 1170 C C . ARG A 1 202 ? 213.513 97.225 18.830 1.00 41.50 ? 200 ARG A C 1 ATOM 1171 O O . ARG A 1 202 ? 214.582 97.711 18.494 1.00 43.67 ? 200 ARG A O 1 ATOM 1172 C CB . ARG A 1 202 ? 212.833 95.246 17.431 1.00 37.86 ? 200 ARG A CB 1 ATOM 1173 C CG . ARG A 1 202 ? 213.681 95.624 16.193 1.00 40.81 ? 200 ARG A CG 1 ATOM 1174 C CD . ARG A 1 202 ? 215.066 94.997 16.206 1.00 37.40 ? 200 ARG A CD 1 ATOM 1175 N NE . ARG A 1 202 ? 215.981 95.759 17.051 1.00 40.06 ? 200 ARG A NE 1 ATOM 1176 C CZ . ARG A 1 202 ? 217.162 95.323 17.470 1.00 53.63 ? 200 ARG A CZ 1 ATOM 1177 N NH1 . ARG A 1 202 ? 217.589 94.113 17.132 1.00 42.34 ? 200 ARG A NH1 1 ATOM 1178 N NH2 . ARG A 1 202 ? 217.924 96.090 18.232 1.00 40.79 ? 200 ARG A NH2 1 ATOM 1179 N N . PHE A 1 203 ? 212.477 97.966 19.214 1.00 36.32 ? 201 PHE A N 1 ATOM 1180 C CA . PHE A 1 203 ? 212.559 99.413 19.271 1.00 36.01 ? 201 PHE A CA 1 ATOM 1181 C C . PHE A 1 203 ? 213.511 99.895 20.364 1.00 41.75 ? 201 PHE A C 1 ATOM 1182 O O . PHE A 1 203 ? 214.255 100.841 20.122 1.00 42.99 ? 201 PHE A O 1 ATOM 1183 C CB . PHE A 1 203 ? 211.172 100.022 19.459 1.00 37.82 ? 201 PHE A CB 1 ATOM 1184 C CG . PHE A 1 203 ? 211.167 101.513 19.688 1.00 39.69 ? 201 PHE A CG 1 ATOM 1185 C CD1 . PHE A 1 203 ? 211.293 102.037 20.971 1.00 43.43 ? 201 PHE A CD1 1 ATOM 1186 C CD2 . PHE A 1 203 ? 211.012 102.394 18.624 1.00 41.23 ? 201 PHE A CD2 1 ATOM 1187 C CE1 . PHE A 1 203 ? 211.297 103.420 21.179 1.00 44.12 ? 201 PHE A CE1 1 ATOM 1188 C CE2 . PHE A 1 203 ? 210.983 103.770 18.838 1.00 44.07 ? 201 PHE A CE2 1 ATOM 1189 C CZ . PHE A 1 203 ? 211.119 104.275 20.113 1.00 42.28 ? 201 PHE A CZ 1 ATOM 1190 N N . PHE A 1 204 ? 213.440 99.294 21.568 1.00 37.52 ? 202 PHE A N 1 ATOM 1191 C CA . PHE A 1 204 ? 214.255 99.642 22.734 1.00 36.61 ? 202 PHE A CA 1 ATOM 1192 C C . PHE A 1 204 ? 215.543 98.820 22.774 1.00 40.94 ? 202 PHE A C 1 ATOM 1193 O O . PHE A 1 204 ? 216.223 98.782 23.805 1.00 39.43 ? 202 PHE A O 1 ATOM 1194 C CB . PHE A 1 204 ? 213.460 99.407 24.034 1.00 37.89 ? 202 PHE A CB 1 ATOM 1195 C CG . PHE A 1 204 ? 212.267 100.290 24.242 1.00 39.04 ? 202 PHE A CG 1 ATOM 1196 C CD1 . PHE A 1 204 ? 212.420 101.661 24.439 1.00 41.91 ? 202 PHE A CD1 1 ATOM 1197 C CD2 . PHE A 1 204 ? 210.990 99.752 24.310 1.00 41.05 ? 202 PHE A CD2 1 ATOM 1198 C CE1 . PHE A 1 204 ? 211.307 102.490 24.614 1.00 41.61 ? 202 PHE A CE1 1 ATOM 1199 C CE2 . PHE A 1 204 ? 209.881 100.578 24.524 1.00 43.53 ? 202 PHE A CE2 1 ATOM 1200 C CZ . PHE A 1 204 ? 210.050 101.944 24.665 1.00 40.80 ? 202 PHE A CZ 1 ATOM 1201 N N . ASN A 1 205 ? 215.838 98.107 21.675 1.00 39.62 ? 203 ASN A N 1 ATOM 1202 C CA . ASN A 1 205 ? 217.032 97.266 21.500 1.00 40.27 ? 203 ASN A CA 1 ATOM 1203 C C . ASN A 1 205 ? 217.178 96.187 22.608 1.00 45.49 ? 203 ASN A C 1 ATOM 1204 O O . ASN A 1 205 ? 218.295 95.801 22.968 1.00 46.20 ? 203 ASN A O 1 ATOM 1205 C CB . ASN A 1 205 ? 218.299 98.143 21.335 1.00 40.07 ? 203 ASN A CB 1 ATOM 1206 C CG . ASN A 1 205 ? 218.215 99.106 20.161 1.00 71.67 ? 203 ASN A CG 1 ATOM 1207 O OD1 . ASN A 1 205 ? 217.830 98.716 19.052 1.00 66.47 ? 203 ASN A OD1 1 ATOM 1208 N ND2 . ASN A 1 205 ? 218.568 100.393 20.358 1.00 69.16 ? 203 ASN A ND2 1 ATOM 1209 N N . TRP A 1 206 ? 216.032 95.675 23.101 1.00 41.98 ? 204 TRP A N 1 ATOM 1210 C CA . TRP A 1 206 ? 215.952 94.599 24.091 1.00 42.16 ? 204 TRP A CA 1 ATOM 1211 C C . TRP A 1 206 ? 216.107 93.280 23.344 1.00 46.79 ? 204 TRP A C 1 ATOM 1212 O O . TRP A 1 206 ? 215.135 92.665 22.905 1.00 48.19 ? 204 TRP A O 1 ATOM 1213 C CB . TRP A 1 206 ? 214.623 94.675 24.853 1.00 41.04 ? 204 TRP A CB 1 ATOM 1214 C CG . TRP A 1 206 ? 214.519 95.846 25.789 1.00 41.76 ? 204 TRP A CG 1 ATOM 1215 C CD1 . TRP A 1 206 ? 215.546 96.508 26.400 1.00 44.42 ? 204 TRP A CD1 1 ATOM 1216 C CD2 . TRP A 1 206 ? 213.312 96.402 26.320 1.00 41.36 ? 204 TRP A CD2 1 ATOM 1217 N NE1 . TRP A 1 206 ? 215.052 97.457 27.258 1.00 43.48 ? 204 TRP A NE1 1 ATOM 1218 C CE2 . TRP A 1 206 ? 213.684 97.411 27.236 1.00 44.71 ? 204 TRP A CE2 1 ATOM 1219 C CE3 . TRP A 1 206 ? 211.950 96.129 26.128 1.00 42.41 ? 204 TRP A CE3 1 ATOM 1220 C CZ2 . TRP A 1 206 ? 212.744 98.157 27.947 1.00 43.81 ? 204 TRP A CZ2 1 ATOM 1221 C CZ3 . TRP A 1 206 ? 211.018 96.878 26.820 1.00 44.02 ? 204 TRP A CZ3 1 ATOM 1222 C CH2 . TRP A 1 206 ? 211.418 97.872 27.728 1.00 44.71 ? 204 TRP A CH2 1 ATOM 1223 N N . THR A 1 207 ? 217.359 92.872 23.183 1.00 42.13 ? 205 THR A N 1 ATOM 1224 C CA . THR A 1 207 ? 217.792 91.769 22.344 1.00 40.61 ? 205 THR A CA 1 ATOM 1225 C C . THR A 1 207 ? 218.046 90.478 23.109 1.00 40.54 ? 205 THR A C 1 ATOM 1226 O O . THR A 1 207 ? 218.229 89.449 22.469 1.00 40.61 ? 205 THR A O 1 ATOM 1227 C CB . THR A 1 207 ? 218.985 92.312 21.552 1.00 52.73 ? 205 THR A CB 1 ATOM 1228 O OG1 . THR A 1 207 ? 218.450 93.182 20.544 1.00 48.86 ? 205 THR A OG1 1 ATOM 1229 C CG2 . THR A 1 207 ? 219.839 91.244 20.907 1.00 56.88 ? 205 THR A CG2 1 ATOM 1230 N N . TYR A 1 208 ? 217.987 90.492 24.439 1.00 35.73 ? 206 TYR A N 1 ATOM 1231 C CA . TYR A 1 208 ? 218.173 89.268 25.238 1.00 35.59 ? 206 TYR A CA 1 ATOM 1232 C C . TYR A 1 208 ? 217.063 89.243 26.290 1.00 40.27 ? 206 TYR A C 1 ATOM 1233 O O . TYR A 1 208 ? 217.110 89.988 27.277 1.00 42.67 ? 206 TYR A O 1 ATOM 1234 C CB . TYR A 1 208 ? 219.593 89.214 25.843 1.00 36.09 ? 206 TYR A CB 1 ATOM 1235 C CG . TYR A 1 208 ? 219.963 87.920 26.532 1.00 37.00 ? 206 TYR A CG 1 ATOM 1236 C CD1 . TYR A 1 208 ? 220.047 86.728 25.821 1.00 39.55 ? 206 TYR A CD1 1 ATOM 1237 C CD2 . TYR A 1 208 ? 220.313 87.901 27.878 1.00 36.99 ? 206 TYR A CD2 1 ATOM 1238 C CE1 . TYR A 1 208 ? 220.421 85.534 26.447 1.00 41.66 ? 206 TYR A CE1 1 ATOM 1239 C CE2 . TYR A 1 208 ? 220.676 86.715 28.518 1.00 37.19 ? 206 TYR A CE2 1 ATOM 1240 C CZ . TYR A 1 208 ? 220.752 85.538 27.796 1.00 46.75 ? 206 TYR A CZ 1 ATOM 1241 O OH . TYR A 1 208 ? 221.113 84.365 28.431 1.00 48.22 ? 206 TYR A OH 1 ATOM 1242 N N . VAL A 1 209 ? 216.005 88.474 26.007 1.00 32.86 ? 207 VAL A N 1 ATOM 1243 C CA . VAL A 1 209 ? 214.798 88.423 26.841 1.00 30.76 ? 207 VAL A CA 1 ATOM 1244 C C . VAL A 1 209 ? 214.488 87.027 27.397 1.00 33.48 ? 207 VAL A C 1 ATOM 1245 O O . VAL A 1 209 ? 215.113 86.046 27.003 1.00 33.20 ? 207 VAL A O 1 ATOM 1246 C CB . VAL A 1 209 ? 213.567 89.015 26.097 1.00 32.29 ? 207 VAL A CB 1 ATOM 1247 C CG1 . VAL A 1 209 ? 213.840 90.433 25.633 1.00 32.28 ? 207 VAL A CG1 1 ATOM 1248 C CG2 . VAL A 1 209 ? 213.123 88.129 24.928 1.00 31.27 ? 207 VAL A CG2 1 ATOM 1249 N N . SER A 1 210 ? 213.515 86.964 28.310 1.00 28.65 ? 208 SER A N 1 ATOM 1250 C CA . SER A 1 210 ? 212.990 85.734 28.874 1.00 28.75 ? 208 SER A CA 1 ATOM 1251 C C . SER A 1 210 ? 211.514 85.731 28.582 1.00 31.18 ? 208 SER A C 1 ATOM 1252 O O . SER A 1 210 ? 210.918 86.786 28.325 1.00 30.35 ? 208 SER A O 1 ATOM 1253 C CB . SER A 1 210 ? 213.219 85.673 30.380 1.00 35.31 ? 208 SER A CB 1 ATOM 1254 O OG . SER A 1 210 ? 214.575 85.390 30.690 1.00 52.98 ? 208 SER A OG 1 ATOM 1255 N N . THR A 1 211 ? 210.919 84.550 28.582 1.00 27.42 ? 209 THR A N 1 ATOM 1256 C CA . THR A 1 211 ? 209.499 84.420 28.281 1.00 26.78 ? 209 THR A CA 1 ATOM 1257 C C . THR A 1 211 ? 208.815 83.644 29.363 1.00 29.33 ? 209 THR A C 1 ATOM 1258 O O . THR A 1 211 ? 209.449 82.804 30.015 1.00 29.81 ? 209 THR A O 1 ATOM 1259 C CB . THR A 1 211 ? 209.238 83.789 26.873 1.00 31.90 ? 209 THR A CB 1 ATOM 1260 O OG1 . THR A 1 211 ? 209.826 82.503 26.796 1.00 34.03 ? 209 THR A OG1 1 ATOM 1261 C CG2 . THR A 1 211 ? 209.763 84.631 25.721 1.00 28.66 ? 209 THR A CG2 1 ATOM 1262 N N . VAL A 1 212 ? 207.525 83.955 29.580 1.00 23.39 ? 210 VAL A N 1 ATOM 1263 C CA . VAL A 1 212 ? 206.643 83.259 30.506 1.00 22.71 ? 210 VAL A CA 1 ATOM 1264 C C . VAL A 1 212 ? 205.349 83.092 29.765 1.00 27.27 ? 210 VAL A C 1 ATOM 1265 O O . VAL A 1 212 ? 204.762 84.053 29.271 1.00 27.55 ? 210 VAL A O 1 ATOM 1266 C CB . VAL A 1 212 ? 206.450 83.885 31.920 1.00 26.26 ? 210 VAL A CB 1 ATOM 1267 C CG1 . VAL A 1 212 ? 205.701 82.922 32.848 1.00 25.60 ? 210 VAL A CG1 1 ATOM 1268 C CG2 . VAL A 1 212 ? 207.780 84.309 32.547 1.00 25.57 ? 210 VAL A CG2 1 ATOM 1269 N N . ALA A 1 213 ? 204.950 81.853 29.602 1.00 24.62 ? 211 ALA A N 1 ATOM 1270 C CA . ALA A 1 213 ? 203.742 81.545 28.856 1.00 23.55 ? 211 ALA A CA 1 ATOM 1271 C C . ALA A 1 213 ? 202.833 80.673 29.713 1.00 25.87 ? 211 ALA A C 1 ATOM 1272 O O . ALA A 1 213 ? 203.314 79.694 30.278 1.00 25.24 ? 211 ALA A O 1 ATOM 1273 C CB . ALA A 1 213 ? 204.111 80.804 27.557 1.00 23.24 ? 211 ALA A CB 1 ATOM 1274 N N . SER A 1 214 ? 201.527 81.008 29.792 1.00 20.59 ? 212 SER A N 1 ATOM 1275 C CA . SER A 1 214 ? 200.561 80.135 30.452 1.00 20.32 ? 212 SER A CA 1 ATOM 1276 C C . SER A 1 214 ? 200.421 78.909 29.559 1.00 28.51 ? 212 SER A C 1 ATOM 1277 O O . SER A 1 214 ? 200.444 79.019 28.336 1.00 30.63 ? 212 SER A O 1 ATOM 1278 C CB . SER A 1 214 ? 199.203 80.814 30.579 1.00 21.04 ? 212 SER A CB 1 ATOM 1279 O OG . SER A 1 214 ? 199.209 81.881 31.514 1.00 27.94 ? 212 SER A OG 1 ATOM 1280 N N . GLU A 1 215 ? 200.338 77.746 30.154 1.00 27.97 ? 213 GLU A N 1 ATOM 1281 C CA . GLU A 1 215 ? 200.126 76.494 29.441 1.00 29.07 ? 213 GLU A CA 1 ATOM 1282 C C . GLU A 1 215 ? 198.762 76.608 28.734 1.00 31.75 ? 213 GLU A C 1 ATOM 1283 O O . GLU A 1 215 ? 197.827 77.213 29.291 1.00 30.82 ? 213 GLU A O 1 ATOM 1284 C CB . GLU A 1 215 ? 200.076 75.349 30.463 1.00 31.40 ? 213 GLU A CB 1 ATOM 1285 C CG . GLU A 1 215 ? 201.090 74.250 30.197 1.00 55.00 ? 213 GLU A CG 1 ATOM 1286 C CD . GLU A 1 215 ? 201.440 73.340 31.363 1.00 90.14 ? 213 GLU A CD 1 ATOM 1287 O OE1 . GLU A 1 215 ? 200.590 72.502 31.745 1.00 85.18 ? 213 GLU A OE1 1 ATOM 1288 O OE2 . GLU A 1 215 ? 202.584 73.436 31.865 1.00 87.32 ? 213 GLU A OE2 1 ATOM 1289 N N . GLY A 1 216 ? 198.674 76.073 27.516 1.00 27.42 ? 214 GLY A N 1 ATOM 1290 C CA . GLY A 1 216 ? 197.443 76.117 26.733 1.00 26.91 ? 214 GLY A CA 1 ATOM 1291 C C . GLY A 1 216 ? 197.504 76.925 25.447 1.00 30.50 ? 214 GLY A C 1 ATOM 1292 O O . GLY A 1 216 ? 198.525 77.529 25.097 1.00 30.65 ? 214 GLY A O 1 ATOM 1293 N N . ASP A 1 217 ? 196.383 76.974 24.766 1.00 25.88 ? 215 ASP A N 1 ATOM 1294 C CA . ASP A 1 217 ? 196.249 77.564 23.448 1.00 25.49 ? 215 ASP A CA 1 ATOM 1295 C C . ASP A 1 217 ? 196.485 79.044 23.352 1.00 28.15 ? 215 ASP A C 1 ATOM 1296 O O . ASP A 1 217 ? 196.903 79.492 22.287 1.00 29.34 ? 215 ASP A O 1 ATOM 1297 C CB . ASP A 1 217 ? 194.896 77.210 22.870 1.00 28.29 ? 215 ASP A CB 1 ATOM 1298 C CG . ASP A 1 217 ? 194.696 75.700 22.831 1.00 42.62 ? 215 ASP A CG 1 ATOM 1299 O OD1 . ASP A 1 217 ? 195.471 75.010 22.091 1.00 39.75 ? 215 ASP A OD1 1 ATOM 1300 O OD2 . ASP A 1 217 ? 193.804 75.198 23.581 1.00 50.05 ? 215 ASP A OD2 1 ATOM 1301 N N . TYR A 1 218 ? 196.258 79.809 24.421 1.00 21.48 ? 216 TYR A N 1 ATOM 1302 C CA . TYR A 1 218 ? 196.544 81.234 24.356 1.00 20.36 ? 216 TYR A CA 1 ATOM 1303 C C . TYR A 1 218 ? 198.058 81.490 24.581 1.00 26.15 ? 216 TYR A C 1 ATOM 1304 O O . TYR A 1 218 ? 198.727 82.078 23.723 1.00 24.68 ? 216 TYR A O 1 ATOM 1305 C CB . TYR A 1 218 ? 195.668 82.025 25.352 1.00 19.88 ? 216 TYR A CB 1 ATOM 1306 C CG . TYR A 1 218 ? 196.132 83.453 25.581 1.00 19.10 ? 216 TYR A CG 1 ATOM 1307 C CD1 . TYR A 1 218 ? 195.779 84.473 24.700 1.00 20.19 ? 216 TYR A CD1 1 ATOM 1308 C CD2 . TYR A 1 218 ? 196.889 83.791 26.699 1.00 18.04 ? 216 TYR A CD2 1 ATOM 1309 C CE1 . TYR A 1 218 ? 196.147 85.793 24.939 1.00 19.95 ? 216 TYR A CE1 1 ATOM 1310 C CE2 . TYR A 1 218 ? 197.285 85.103 26.935 1.00 18.15 ? 216 TYR A CE2 1 ATOM 1311 C CZ . TYR A 1 218 ? 196.925 86.103 26.046 1.00 26.78 ? 216 TYR A CZ 1 ATOM 1312 O OH . TYR A 1 218 ? 197.290 87.413 26.302 1.00 25.98 ? 216 TYR A OH 1 ATOM 1313 N N . GLY A 1 219 ? 198.552 81.077 25.747 1.00 24.62 ? 217 GLY A N 1 ATOM 1314 C CA . GLY A 1 219 ? 199.939 81.262 26.137 1.00 25.32 ? 217 GLY A CA 1 ATOM 1315 C C . GLY A 1 219 ? 200.978 80.638 25.230 1.00 31.25 ? 217 GLY A C 1 ATOM 1316 O O . GLY A 1 219 ? 201.921 81.321 24.797 1.00 30.76 ? 217 GLY A O 1 ATOM 1317 N N . GLU A 1 220 ? 200.817 79.341 24.939 1.00 29.97 ? 218 GLU A N 1 ATOM 1318 C CA . GLU A 1 220 ? 201.792 78.577 24.143 1.00 29.95 ? 218 GLU A CA 1 ATOM 1319 C C . GLU A 1 220 ? 201.854 79.000 22.689 1.00 34.72 ? 218 GLU A C 1 ATOM 1320 O O . GLU A 1 220 ? 202.961 79.198 22.159 1.00 35.54 ? 218 GLU A O 1 ATOM 1321 C CB . GLU A 1 220 ? 201.585 77.077 24.288 1.00 30.85 ? 218 GLU A CB 1 ATOM 1322 C CG . GLU A 1 220 ? 201.790 76.654 25.738 1.00 45.42 ? 218 GLU A CG 1 ATOM 1323 C CD . GLU A 1 220 ? 201.856 75.164 25.998 1.00 76.73 ? 218 GLU A CD 1 ATOM 1324 O OE1 . GLU A 1 220 ? 202.913 74.560 25.703 1.00 71.77 ? 218 GLU A OE1 1 ATOM 1325 O OE2 . GLU A 1 220 ? 200.865 74.605 26.526 1.00 75.91 ? 218 GLU A OE2 1 ATOM 1326 N N . THR A 1 221 ? 200.692 79.212 22.061 1.00 29.60 ? 219 THR A N 1 ATOM 1327 C CA . THR A 1 221 ? 200.687 79.613 20.660 1.00 28.81 ? 219 THR A CA 1 ATOM 1328 C C . THR A 1 221 ? 201.115 81.077 20.558 1.00 32.18 ? 219 THR A C 1 ATOM 1329 O O . THR A 1 221 ? 201.829 81.414 19.609 1.00 35.00 ? 219 THR A O 1 ATOM 1330 C CB . THR A 1 221 ? 199.377 79.220 19.942 1.00 36.97 ? 219 THR A CB 1 ATOM 1331 O OG1 . THR A 1 221 ? 198.342 80.157 20.177 1.00 43.22 ? 219 THR A OG1 1 ATOM 1332 C CG2 . THR A 1 221 ? 198.889 77.871 20.359 1.00 32.52 ? 219 THR A CG2 1 ATOM 1333 N N . GLY A 1 222 ? 200.749 81.891 21.563 1.00 24.52 ? 220 GLY A N 1 ATOM 1334 C CA . GLY A 1 222 ? 201.119 83.296 21.684 1.00 22.53 ? 220 GLY A CA 1 ATOM 1335 C C . GLY A 1 222 ? 202.621 83.553 21.708 1.00 23.98 ? 220 GLY A C 1 ATOM 1336 O O . GLY A 1 222 ? 203.129 84.346 20.906 1.00 22.19 ? 220 GLY A O 1 ATOM 1337 N N . ILE A 1 223 ? 203.335 82.911 22.641 1.00 22.08 ? 221 ILE A N 1 ATOM 1338 C CA . ILE A 1 223 ? 204.801 83.010 22.811 1.00 22.99 ? 221 ILE A CA 1 ATOM 1339 C C . ILE A 1 223 ? 205.564 82.386 21.623 1.00 28.87 ? 221 ILE A C 1 ATOM 1340 O O . ILE A 1 223 ? 206.547 82.996 21.200 1.00 29.70 ? 221 ILE A O 1 ATOM 1341 C CB . ILE A 1 223 ? 205.274 82.466 24.205 1.00 26.07 ? 221 ILE A CB 1 ATOM 1342 C CG1 . ILE A 1 223 ? 205.309 83.572 25.296 1.00 26.47 ? 221 ILE A CG1 1 ATOM 1343 C CG2 . ILE A 1 223 ? 206.587 81.752 24.156 1.00 26.98 ? 221 ILE A CG2 1 ATOM 1344 C CD1 . ILE A 1 223 ? 206.092 84.925 25.023 1.00 32.36 ? 221 ILE A CD1 1 ATOM 1345 N N . GLU A 1 224 ? 205.129 81.213 21.070 1.00 25.71 ? 222 GLU A N 1 ATOM 1346 C CA . GLU A 1 224 ? 205.806 80.629 19.891 1.00 27.45 ? 222 GLU A CA 1 ATOM 1347 C C . GLU A 1 224 ? 205.836 81.655 18.740 1.00 28.76 ? 222 GLU A C 1 ATOM 1348 O O . GLU A 1 224 ? 206.908 81.965 18.220 1.00 28.20 ? 222 GLU A O 1 ATOM 1349 C CB . GLU A 1 224 ? 205.104 79.340 19.436 1.00 30.33 ? 222 GLU A CB 1 ATOM 1350 C CG . GLU A 1 224 ? 205.739 78.646 18.232 1.00 47.62 ? 222 GLU A CG 1 ATOM 1351 C CD . GLU A 1 224 ? 205.034 77.390 17.731 1.00 81.09 ? 222 GLU A CD 1 ATOM 1352 O OE1 . GLU A 1 224 ? 204.501 76.612 18.560 1.00 75.23 ? 222 GLU A OE1 1 ATOM 1353 O OE2 . GLU A 1 224 ? 205.056 77.166 16.498 1.00 76.87 ? 222 GLU A OE2 1 ATOM 1354 N N . ALA A 1 225 ? 204.655 82.222 18.405 1.00 23.68 ? 223 ALA A N 1 ATOM 1355 C CA . ALA A 1 225 ? 204.500 83.286 17.417 1.00 23.42 ? 223 ALA A CA 1 ATOM 1356 C C . ALA A 1 225 ? 205.424 84.484 17.756 1.00 30.08 ? 223 ALA A C 1 ATOM 1357 O O . ALA A 1 225 ? 206.020 85.053 16.839 1.00 31.73 ? 223 ALA A O 1 ATOM 1358 C CB . ALA A 1 225 ? 203.046 83.740 17.349 1.00 23.18 ? 223 ALA A CB 1 ATOM 1359 N N . PHE A 1 226 ? 205.552 84.852 19.070 1.00 24.63 ? 224 PHE A N 1 ATOM 1360 C CA . PHE A 1 226 ? 206.423 85.942 19.531 1.00 22.75 ? 224 PHE A CA 1 ATOM 1361 C C . PHE A 1 226 ? 207.901 85.584 19.221 1.00 26.27 ? 224 PHE A C 1 ATOM 1362 O O . PHE A 1 226 ? 208.601 86.382 18.602 1.00 24.97 ? 224 PHE A O 1 ATOM 1363 C CB . PHE A 1 226 ? 206.200 86.285 21.042 1.00 22.68 ? 224 PHE A CB 1 ATOM 1364 C CG . PHE A 1 226 ? 207.372 87.032 21.623 1.00 21.21 ? 224 PHE A CG 1 ATOM 1365 C CD1 . PHE A 1 226 ? 207.582 88.368 21.316 1.00 22.75 ? 224 PHE A CD1 1 ATOM 1366 C CD2 . PHE A 1 226 ? 208.340 86.365 22.357 1.00 22.46 ? 224 PHE A CD2 1 ATOM 1367 C CE1 . PHE A 1 226 ? 208.735 89.020 21.729 1.00 23.79 ? 224 PHE A CE1 1 ATOM 1368 C CE2 . PHE A 1 226 ? 209.489 87.019 22.781 1.00 25.11 ? 224 PHE A CE2 1 ATOM 1369 C CZ . PHE A 1 226 ? 209.683 88.338 22.456 1.00 23.28 ? 224 PHE A CZ 1 ATOM 1370 N N . GLU A 1 227 ? 208.336 84.382 19.625 1.00 23.05 ? 225 GLU A N 1 ATOM 1371 C CA . GLU A 1 227 ? 209.677 83.877 19.362 1.00 24.47 ? 225 GLU A CA 1 ATOM 1372 C C . GLU A 1 227 ? 210.073 83.933 17.872 1.00 30.40 ? 225 GLU A C 1 ATOM 1373 O O . GLU A 1 227 ? 211.167 84.408 17.553 1.00 31.25 ? 225 GLU A O 1 ATOM 1374 C CB . GLU A 1 227 ? 209.845 82.454 19.908 1.00 26.27 ? 225 GLU A CB 1 ATOM 1375 C CG . GLU A 1 227 ? 210.083 82.385 21.415 1.00 39.22 ? 225 GLU A CG 1 ATOM 1376 C CD . GLU A 1 227 ? 209.865 81.030 22.069 1.00 60.90 ? 225 GLU A CD 1 ATOM 1377 O OE1 . GLU A 1 227 ? 209.714 80.022 21.339 1.00 65.52 ? 225 GLU A OE1 1 ATOM 1378 O OE2 . GLU A 1 227 ? 209.821 80.983 23.321 1.00 49.72 ? 225 GLU A OE2 1 ATOM 1379 N N . LEU A 1 228 ? 209.200 83.478 16.961 1.00 26.08 ? 226 LEU A N 1 ATOM 1380 C CA . LEU A 1 228 ? 209.547 83.531 15.531 1.00 25.41 ? 226 LEU A CA 1 ATOM 1381 C C . LEU A 1 228 ? 209.761 85.001 15.064 1.00 31.36 ? 226 LEU A C 1 ATOM 1382 O O . LEU A 1 228 ? 210.741 85.294 14.375 1.00 31.76 ? 226 LEU A O 1 ATOM 1383 C CB . LEU A 1 228 ? 208.509 82.783 14.681 1.00 24.11 ? 226 LEU A CB 1 ATOM 1384 C CG . LEU A 1 228 ? 208.445 81.288 14.954 1.00 26.02 ? 226 LEU A CG 1 ATOM 1385 C CD1 . LEU A 1 228 ? 207.086 80.724 14.638 1.00 23.85 ? 226 LEU A CD1 1 ATOM 1386 C CD2 . LEU A 1 228 ? 209.560 80.548 14.242 1.00 29.42 ? 226 LEU A CD2 1 ATOM 1387 N N . GLU A 1 229 ? 208.908 85.922 15.538 1.00 27.76 ? 227 GLU A N 1 ATOM 1388 C CA . GLU A 1 229 ? 209.004 87.363 15.241 1.00 27.36 ? 227 GLU A CA 1 ATOM 1389 C C . GLU A 1 229 ? 210.275 87.995 15.799 1.00 31.72 ? 227 GLU A C 1 ATOM 1390 O O . GLU A 1 229 ? 210.866 88.849 15.139 1.00 30.54 ? 227 GLU A O 1 ATOM 1391 C CB . GLU A 1 229 ? 207.769 88.121 15.771 1.00 27.90 ? 227 GLU A CB 1 ATOM 1392 C CG . GLU A 1 229 ? 206.460 87.750 15.112 1.00 30.80 ? 227 GLU A CG 1 ATOM 1393 C CD . GLU A 1 229 ? 206.372 87.882 13.604 1.00 49.86 ? 227 GLU A CD 1 ATOM 1394 O OE1 . GLU A 1 229 ? 206.964 88.824 13.030 1.00 38.60 ? 227 GLU A OE1 1 ATOM 1395 O OE2 . GLU A 1 229 ? 205.655 87.061 12.996 1.00 57.11 ? 227 GLU A OE2 1 ATOM 1396 N N . ALA A 1 230 ? 210.671 87.581 17.028 1.00 30.62 ? 228 ALA A N 1 ATOM 1397 C CA . ALA A 1 230 ? 211.850 88.052 17.763 1.00 31.07 ? 228 ALA A CA 1 ATOM 1398 C C . ALA A 1 230 ? 213.139 87.581 17.096 1.00 35.84 ? 228 ALA A C 1 ATOM 1399 O O . ALA A 1 230 ? 214.009 88.408 16.853 1.00 36.61 ? 228 ALA A O 1 ATOM 1400 C CB . ALA A 1 230 ? 211.789 87.581 19.200 1.00 32.18 ? 228 ALA A CB 1 ATOM 1401 N N . ARG A 1 231 ? 213.237 86.275 16.741 1.00 31.75 ? 229 ARG A N 1 ATOM 1402 C CA . ARG A 1 231 ? 214.366 85.683 16.005 1.00 31.98 ? 229 ARG A CA 1 ATOM 1403 C C . ARG A 1 231 ? 214.692 86.555 14.769 1.00 39.87 ? 229 ARG A C 1 ATOM 1404 O O . ARG A 1 231 ? 215.816 87.055 14.634 1.00 41.21 ? 229 ARG A O 1 ATOM 1405 C CB . ARG A 1 231 ? 214.002 84.269 15.544 1.00 29.75 ? 229 ARG A CB 1 ATOM 1406 C CG . ARG A 1 231 ? 215.186 83.403 15.166 1.00 41.12 ? 229 ARG A CG 1 ATOM 1407 C CD . ARG A 1 231 ? 214.728 82.091 14.560 1.00 51.28 ? 229 ARG A CD 1 ATOM 1408 N NE . ARG A 1 231 ? 213.993 81.268 15.520 1.00 63.49 ? 229 ARG A NE 1 ATOM 1409 C CZ . ARG A 1 231 ? 213.174 80.278 15.178 1.00 79.92 ? 229 ARG A CZ 1 ATOM 1410 N NH1 . ARG A 1 231 ? 212.980 79.979 13.895 1.00 64.06 ? 229 ARG A NH1 1 ATOM 1411 N NH2 . ARG A 1 231 ? 212.534 79.582 16.115 1.00 63.09 ? 229 ARG A NH2 1 ATOM 1412 N N . ALA A 1 232 ? 213.664 86.810 13.927 1.00 35.62 ? 230 ALA A N 1 ATOM 1413 C CA . ALA A 1 232 ? 213.735 87.641 12.737 1.00 34.40 ? 230 ALA A CA 1 ATOM 1414 C C . ALA A 1 232 ? 214.251 89.072 13.006 1.00 42.24 ? 230 ALA A C 1 ATOM 1415 O O . ALA A 1 232 ? 214.606 89.768 12.051 1.00 43.89 ? 230 ALA A O 1 ATOM 1416 C CB . ALA A 1 232 ? 212.376 87.682 12.075 1.00 34.35 ? 230 ALA A CB 1 ATOM 1417 N N . ARG A 1 233 ? 214.295 89.518 14.291 1.00 38.08 ? 231 ARG A N 1 ATOM 1418 C CA . ARG A 1 233 ? 214.778 90.860 14.648 1.00 36.46 ? 231 ARG A CA 1 ATOM 1419 C C . ARG A 1 233 ? 216.045 90.769 15.498 1.00 39.27 ? 231 ARG A C 1 ATOM 1420 O O . ARG A 1 233 ? 216.477 91.737 16.121 1.00 37.86 ? 231 ARG A O 1 ATOM 1421 C CB . ARG A 1 233 ? 213.669 91.660 15.332 1.00 35.88 ? 231 ARG A CB 1 ATOM 1422 C CG . ARG A 1 233 ? 212.505 91.979 14.392 1.00 44.82 ? 231 ARG A CG 1 ATOM 1423 C CD . ARG A 1 233 ? 211.227 92.251 15.168 1.00 43.77 ? 231 ARG A CD 1 ATOM 1424 N NE . ARG A 1 233 ? 210.155 92.808 14.339 1.00 36.76 ? 231 ARG A NE 1 ATOM 1425 C CZ . ARG A 1 233 ? 209.254 92.083 13.682 1.00 47.63 ? 231 ARG A CZ 1 ATOM 1426 N NH1 . ARG A 1 233 ? 209.312 90.757 13.707 1.00 36.34 ? 231 ARG A NH1 1 ATOM 1427 N NH2 . ARG A 1 233 ? 208.301 92.679 12.977 1.00 29.86 ? 231 ARG A NH2 1 ATOM 1428 N N . ASN A 1 234 ? 216.657 89.584 15.483 1.00 37.77 ? 232 ASN A N 1 ATOM 1429 C CA . ASN A 1 234 ? 217.889 89.227 16.204 1.00 38.82 ? 232 ASN A CA 1 ATOM 1430 C C . ASN A 1 234 ? 217.728 89.411 17.724 1.00 41.66 ? 232 ASN A C 1 ATOM 1431 O O . ASN A 1 234 ? 218.630 89.898 18.399 1.00 42.94 ? 232 ASN A O 1 ATOM 1432 C CB . ASN A 1 234 ? 219.146 89.928 15.622 1.00 42.49 ? 232 ASN A CB 1 ATOM 1433 C CG . ASN A 1 234 ? 219.379 89.636 14.140 1.00 85.17 ? 232 ASN A CG 1 ATOM 1434 O OD1 . ASN A 1 234 ? 219.140 88.518 13.641 1.00 83.66 ? 232 ASN A OD1 1 ATOM 1435 N ND2 . ASN A 1 234 ? 219.855 90.637 13.393 1.00 78.23 ? 232 ASN A ND2 1 ATOM 1436 N N . ILE A 1 235 ? 216.566 88.978 18.248 1.00 34.70 ? 233 ILE A N 1 ATOM 1437 C CA . ILE A 1 235 ? 216.243 89.000 19.665 1.00 32.71 ? 233 ILE A CA 1 ATOM 1438 C C . ILE A 1 235 ? 216.365 87.575 20.088 1.00 37.43 ? 233 ILE A C 1 ATOM 1439 O O . ILE A 1 235 ? 215.736 86.703 19.489 1.00 37.30 ? 233 ILE A O 1 ATOM 1440 C CB . ILE A 1 235 ? 214.841 89.585 19.973 1.00 34.56 ? 233 ILE A CB 1 ATOM 1441 C CG1 . ILE A 1 235 ? 214.711 91.035 19.437 1.00 33.14 ? 233 ILE A CG1 1 ATOM 1442 C CG2 . ILE A 1 235 ? 214.547 89.515 21.495 1.00 34.41 ? 233 ILE A CG2 1 ATOM 1443 C CD1 . ILE A 1 235 ? 213.311 91.548 19.329 1.00 30.71 ? 233 ILE A CD1 1 ATOM 1444 N N . SER A 1 236 ? 217.217 87.313 21.069 1.00 35.76 ? 234 SER A N 1 ATOM 1445 C CA . SER A 1 236 ? 217.421 85.946 21.544 1.00 36.30 ? 234 SER A CA 1 ATOM 1446 C C . SER A 1 236 ? 216.768 85.720 22.913 1.00 37.52 ? 234 SER A C 1 ATOM 1447 O O . SER A 1 236 ? 216.663 86.654 23.712 1.00 36.48 ? 234 SER A O 1 ATOM 1448 C CB . SER A 1 236 ? 218.899 85.558 21.528 1.00 40.69 ? 234 SER A CB 1 ATOM 1449 O OG . SER A 1 236 ? 219.692 86.537 22.178 1.00 54.88 ? 234 SER A OG 1 ATOM 1450 N N . VAL A 1 237 ? 216.277 84.492 23.132 1.00 31.61 ? 235 VAL A N 1 ATOM 1451 C CA . VAL A 1 237 ? 215.608 84.105 24.354 1.00 30.98 ? 235 VAL A CA 1 ATOM 1452 C C . VAL A 1 237 ? 216.567 83.376 25.295 1.00 37.93 ? 235 VAL A C 1 ATOM 1453 O O . VAL A 1 237 ? 217.061 82.278 24.969 1.00 36.49 ? 235 VAL A O 1 ATOM 1454 C CB . VAL A 1 237 ? 214.297 83.305 24.114 1.00 33.07 ? 235 VAL A CB 1 ATOM 1455 C CG1 . VAL A 1 237 ? 213.578 83.026 25.431 1.00 32.59 ? 235 VAL A CG1 1 ATOM 1456 C CG2 . VAL A 1 237 ? 213.370 84.046 23.166 1.00 32.82 ? 235 VAL A CG2 1 ATOM 1457 N N . ALA A 1 238 ? 216.777 83.985 26.491 1.00 35.51 ? 236 ALA A N 1 ATOM 1458 C CA . ALA A 1 238 ? 217.581 83.474 27.601 1.00 35.39 ? 236 ALA A CA 1 ATOM 1459 C C . ALA A 1 238 ? 216.951 82.225 28.155 1.00 41.08 ? 236 ALA A C 1 ATOM 1460 O O . ALA A 1 238 ? 217.602 81.181 28.182 1.00 42.90 ? 236 ALA A O 1 ATOM 1461 C CB . ALA A 1 238 ? 217.676 84.513 28.697 1.00 36.15 ? 236 ALA A CB 1 ATOM 1462 N N . THR A 1 239 ? 215.681 82.317 28.580 1.00 37.91 ? 237 THR A N 1 ATOM 1463 C CA . THR A 1 239 ? 214.944 81.179 29.146 1.00 37.19 ? 237 THR A CA 1 ATOM 1464 C C . THR A 1 239 ? 213.444 81.285 28.887 1.00 36.42 ? 237 THR A C 1 ATOM 1465 O O . THR A 1 239 ? 212.893 82.385 28.828 1.00 35.25 ? 237 THR A O 1 ATOM 1466 C CB . THR A 1 239 ? 215.283 80.938 30.648 1.00 44.38 ? 237 THR A CB 1 ATOM 1467 O OG1 . THR A 1 239 ? 214.643 79.736 31.071 1.00 50.61 ? 237 THR A OG1 1 ATOM 1468 C CG2 . THR A 1 239 ? 214.865 82.082 31.568 1.00 36.96 ? 237 THR A CG2 1 ATOM 1469 N N . SER A 1 240 ? 212.796 80.132 28.755 1.00 30.32 ? 238 SER A N 1 ATOM 1470 C CA . SER A 1 240 ? 211.365 80.052 28.523 1.00 29.39 ? 238 SER A CA 1 ATOM 1471 C C . SER A 1 240 ? 210.750 79.289 29.630 1.00 33.64 ? 238 SER A C 1 ATOM 1472 O O . SER A 1 240 ? 211.201 78.181 29.935 1.00 34.25 ? 238 SER A O 1 ATOM 1473 C CB . SER A 1 240 ? 211.055 79.382 27.195 1.00 31.20 ? 238 SER A CB 1 ATOM 1474 O OG . SER A 1 240 ? 211.422 80.255 26.140 1.00 44.90 ? 238 SER A OG 1 ATOM 1475 N N . GLU A 1 241 ? 209.717 79.878 30.246 1.00 29.17 ? 239 GLU A N 1 ATOM 1476 C CA . GLU A 1 241 ? 208.991 79.254 31.342 1.00 28.57 ? 239 GLU A CA 1 ATOM 1477 C C . GLU A 1 241 ? 207.517 79.049 30.998 1.00 32.48 ? 239 GLU A C 1 ATOM 1478 O O . GLU A 1 241 ? 206.904 79.856 30.277 1.00 31.09 ? 239 GLU A O 1 ATOM 1479 C CB . GLU A 1 241 ? 209.143 80.064 32.650 1.00 29.94 ? 239 GLU A CB 1 ATOM 1480 C CG . GLU A 1 241 ? 210.548 80.108 33.243 1.00 41.77 ? 239 GLU A CG 1 ATOM 1481 C CD . GLU A 1 241 ? 211.121 78.796 33.750 1.00 65.06 ? 239 GLU A CD 1 ATOM 1482 O OE1 . GLU A 1 241 ? 210.416 78.075 34.498 1.00 61.27 ? 239 GLU A OE1 1 ATOM 1483 O OE2 . GLU A 1 241 ? 212.294 78.506 33.419 1.00 55.01 ? 239 GLU A OE2 1 ATOM 1484 N N . LYS A 1 242 ? 206.957 77.968 31.533 1.00 30.63 ? 240 LYS A N 1 ATOM 1485 C CA . LYS A 1 242 ? 205.547 77.621 31.409 1.00 31.61 ? 240 LYS A CA 1 ATOM 1486 C C . LYS A 1 242 ? 204.874 77.657 32.778 1.00 38.89 ? 240 LYS A C 1 ATOM 1487 O O . LYS A 1 242 ? 205.494 77.297 33.791 1.00 39.65 ? 240 LYS A O 1 ATOM 1488 C CB . LYS A 1 242 ? 205.359 76.242 30.798 1.00 33.39 ? 240 LYS A CB 1 ATOM 1489 C CG . LYS A 1 242 ? 205.418 76.220 29.286 1.00 44.15 ? 240 LYS A CG 1 ATOM 1490 C CD . LYS A 1 242 ? 204.295 75.375 28.698 1.00 58.22 ? 240 LYS A CD 1 ATOM 1491 C CE . LYS A 1 242 ? 204.398 73.906 29.036 1.00 71.24 ? 240 LYS A CE 1 ATOM 1492 N NZ . LYS A 1 242 ? 203.465 73.089 28.222 1.00 83.47 ? 240 LYS A NZ 1 ATOM 1493 N N . VAL A 1 243 ? 203.603 78.099 32.798 1.00 34.96 ? 241 VAL A N 1 ATOM 1494 C CA . VAL A 1 243 ? 202.793 78.188 33.999 1.00 33.91 ? 241 VAL A CA 1 ATOM 1495 C C . VAL A 1 243 ? 201.657 77.195 33.862 1.00 37.71 ? 241 VAL A C 1 ATOM 1496 O O . VAL A 1 243 ? 200.864 77.325 32.942 1.00 37.50 ? 241 VAL A O 1 ATOM 1497 C CB . VAL A 1 243 ? 202.288 79.621 34.272 1.00 36.86 ? 241 VAL A CB 1 ATOM 1498 C CG1 . VAL A 1 243 ? 201.321 79.630 35.441 1.00 36.79 ? 241 VAL A CG1 1 ATOM 1499 C CG2 . VAL A 1 243 ? 203.437 80.565 34.548 1.00 36.29 ? 241 VAL A CG2 1 ATOM 1500 N N . GLY A 1 244 ? 201.585 76.238 34.790 1.00 34.52 ? 242 GLY A N 1 ATOM 1501 C CA . GLY A 1 244 ? 200.567 75.191 34.828 1.00 34.48 ? 242 GLY A CA 1 ATOM 1502 C C . GLY A 1 244 ? 199.194 75.692 35.216 1.00 40.88 ? 242 GLY A C 1 ATOM 1503 O O . GLY A 1 244 ? 199.038 76.858 35.588 1.00 40.73 ? 242 GLY A O 1 ATOM 1504 N N . ARG A 1 245 ? 198.180 74.813 35.104 1.00 39.87 ? 243 ARG A N 1 ATOM 1505 C CA . ARG A 1 245 ? 196.780 75.128 35.424 1.00 40.40 ? 243 ARG A CA 1 ATOM 1506 C C . ARG A 1 245 ? 196.599 75.186 36.935 1.00 47.93 ? 243 ARG A C 1 ATOM 1507 O O . ARG A 1 245 ? 195.759 75.944 37.428 1.00 49.37 ? 243 ARG A O 1 ATOM 1508 C CB . ARG A 1 245 ? 195.800 74.115 34.782 1.00 37.06 ? 243 ARG A CB 1 ATOM 1509 N N . ALA A 1 246 ? 197.393 74.394 37.666 1.00 45.11 ? 244 ALA A N 1 ATOM 1510 C CA . ALA A 1 246 ? 197.349 74.313 39.124 1.00 45.81 ? 244 ALA A CA 1 ATOM 1511 C C . ALA A 1 246 ? 198.780 74.486 39.610 1.00 50.52 ? 244 ALA A C 1 ATOM 1512 O O . ALA A 1 246 ? 199.596 73.572 39.432 1.00 52.19 ? 244 ALA A O 1 ATOM 1513 C CB . ALA A 1 246 ? 196.790 72.960 39.556 1.00 46.32 ? 244 ALA A CB 1 ATOM 1514 N N . MET A 1 247 ? 199.109 75.699 40.116 1.00 43.17 ? 245 MET A N 1 ATOM 1515 C CA . MET A 1 247 ? 200.453 76.058 40.586 1.00 41.03 ? 245 MET A CA 1 ATOM 1516 C C . MET A 1 247 ? 200.339 76.682 41.955 1.00 46.68 ? 245 MET A C 1 ATOM 1517 O O . MET A 1 247 ? 199.418 77.484 42.190 1.00 48.98 ? 245 MET A O 1 ATOM 1518 C CB . MET A 1 247 ? 201.116 77.102 39.669 1.00 41.96 ? 245 MET A CB 1 ATOM 1519 C CG . MET A 1 247 ? 201.499 76.616 38.311 1.00 43.70 ? 245 MET A CG 1 ATOM 1520 S SD . MET A 1 247 ? 203.281 76.620 38.034 1.00 46.39 ? 245 MET A SD 1 ATOM 1521 C CE . MET A 1 247 ? 203.679 78.304 38.103 1.00 42.80 ? 245 MET A CE 1 ATOM 1522 N N . SER A 1 248 ? 201.304 76.377 42.839 1.00 40.12 ? 246 SER A N 1 ATOM 1523 C CA . SER A 1 248 ? 201.336 76.942 44.189 1.00 38.26 ? 246 SER A CA 1 ATOM 1524 C C . SER A 1 248 ? 202.141 78.241 44.190 1.00 39.46 ? 246 SER A C 1 ATOM 1525 O O . SER A 1 248 ? 202.855 78.533 43.225 1.00 38.18 ? 246 SER A O 1 ATOM 1526 C CB . SER A 1 248 ? 201.969 75.952 45.164 1.00 39.84 ? 246 SER A CB 1 ATOM 1527 O OG . SER A 1 248 ? 203.350 75.776 44.891 1.00 45.34 ? 246 SER A OG 1 ATOM 1528 N N . ARG A 1 249 ? 202.070 78.979 45.306 1.00 34.72 ? 247 ARG A N 1 ATOM 1529 C CA . ARG A 1 249 ? 202.848 80.188 45.544 1.00 34.31 ? 247 ARG A CA 1 ATOM 1530 C C . ARG A 1 249 ? 204.349 79.831 45.423 1.00 38.83 ? 247 ARG A C 1 ATOM 1531 O O . ARG A 1 249 ? 205.082 80.482 44.661 1.00 38.61 ? 247 ARG A O 1 ATOM 1532 C CB . ARG A 1 249 ? 202.496 80.760 46.914 1.00 32.42 ? 247 ARG A CB 1 ATOM 1533 C CG . ARG A 1 249 ? 201.094 81.343 46.913 1.00 39.08 ? 247 ARG A CG 1 ATOM 1534 C CD . ARG A 1 249 ? 200.874 82.199 48.126 1.00 48.16 ? 247 ARG A CD 1 ATOM 1535 N NE . ARG A 1 249 ? 199.599 82.907 48.068 1.00 60.48 ? 247 ARG A NE 1 ATOM 1536 C CZ . ARG A 1 249 ? 199.225 83.834 48.944 1.00 82.08 ? 247 ARG A CZ 1 ATOM 1537 N NH1 . ARG A 1 249 ? 200.023 84.163 49.956 1.00 76.31 ? 247 ARG A NH1 1 ATOM 1538 N NH2 . ARG A 1 249 ? 198.053 84.442 48.815 1.00 68.42 ? 247 ARG A NH2 1 ATOM 1539 N N . ALA A 1 250 ? 204.754 78.701 46.056 1.00 34.89 ? 248 ALA A N 1 ATOM 1540 C CA . ALA A 1 250 ? 206.110 78.150 45.974 1.00 33.81 ? 248 ALA A CA 1 ATOM 1541 C C . ALA A 1 250 ? 206.522 77.905 44.521 1.00 36.64 ? 248 ALA A C 1 ATOM 1542 O O . ALA A 1 250 ? 207.620 78.303 44.150 1.00 35.38 ? 248 ALA A O 1 ATOM 1543 C CB . ALA A 1 250 ? 206.200 76.858 46.761 1.00 34.21 ? 248 ALA A CB 1 ATOM 1544 N N . ALA A 1 251 ? 205.631 77.287 43.694 1.00 34.31 ? 249 ALA A N 1 ATOM 1545 C CA . ALA A 1 251 ? 205.851 76.965 42.257 1.00 33.61 ? 249 ALA A CA 1 ATOM 1546 C C . ALA A 1 251 ? 206.159 78.237 41.466 1.00 35.84 ? 249 ALA A C 1 ATOM 1547 O O . ALA A 1 251 ? 207.137 78.295 40.702 1.00 34.90 ? 249 ALA A O 1 ATOM 1548 C CB . ALA A 1 251 ? 204.620 76.274 41.683 1.00 34.12 ? 249 ALA A CB 1 ATOM 1549 N N . PHE A 1 252 ? 205.359 79.285 41.727 1.00 31.25 ? 250 PHE A N 1 ATOM 1550 C CA . PHE A 1 252 ? 205.538 80.592 41.124 1.00 30.16 ? 250 PHE A CA 1 ATOM 1551 C C . PHE A 1 252 ? 206.842 81.202 41.524 1.00 35.38 ? 250 PHE A C 1 ATOM 1552 O O . PHE A 1 252 ? 207.506 81.766 40.668 1.00 35.85 ? 250 PHE A O 1 ATOM 1553 C CB . PHE A 1 252 ? 204.375 81.520 41.444 1.00 31.11 ? 250 PHE A CB 1 ATOM 1554 C CG . PHE A 1 252 ? 203.245 81.318 40.476 1.00 32.16 ? 250 PHE A CG 1 ATOM 1555 C CD1 . PHE A 1 252 ? 203.341 81.780 39.162 1.00 34.20 ? 250 PHE A CD1 1 ATOM 1556 C CD2 . PHE A 1 252 ? 202.079 80.670 40.870 1.00 33.48 ? 250 PHE A CD2 1 ATOM 1557 C CE1 . PHE A 1 252 ? 202.272 81.636 38.274 1.00 34.28 ? 250 PHE A CE1 1 ATOM 1558 C CE2 . PHE A 1 252 ? 201.017 80.511 39.977 1.00 35.83 ? 250 PHE A CE2 1 ATOM 1559 C CZ . PHE A 1 252 ? 201.120 81.000 38.685 1.00 33.37 ? 250 PHE A CZ 1 ATOM 1560 N N . GLU A 1 253 ? 207.250 81.057 42.800 1.00 32.76 ? 251 GLU A N 1 ATOM 1561 C CA . GLU A 1 253 ? 208.549 81.569 43.257 1.00 32.43 ? 251 GLU A CA 1 ATOM 1562 C C . GLU A 1 253 ? 209.719 80.926 42.483 1.00 33.27 ? 251 GLU A C 1 ATOM 1563 O O . GLU A 1 253 ? 210.650 81.626 42.080 1.00 30.95 ? 251 GLU A O 1 ATOM 1564 C CB . GLU A 1 253 ? 208.699 81.372 44.757 1.00 33.89 ? 251 GLU A CB 1 ATOM 1565 C CG . GLU A 1 253 ? 208.024 82.471 45.552 1.00 41.94 ? 251 GLU A CG 1 ATOM 1566 C CD . GLU A 1 253 ? 207.304 82.035 46.815 1.00 50.99 ? 251 GLU A CD 1 ATOM 1567 O OE1 . GLU A 1 253 ? 206.434 82.805 47.280 1.00 32.40 ? 251 GLU A OE1 1 ATOM 1568 O OE2 . GLU A 1 253 ? 207.583 80.927 47.329 1.00 43.14 ? 251 GLU A OE2 1 ATOM 1569 N N . GLY A 1 254 ? 209.576 79.630 42.204 1.00 30.03 ? 252 GLY A N 1 ATOM 1570 C CA . GLY A 1 254 ? 210.514 78.816 41.448 1.00 30.61 ? 252 GLY A CA 1 ATOM 1571 C C . GLY A 1 254 ? 210.668 79.266 40.016 1.00 39.27 ? 252 GLY A C 1 ATOM 1572 O O . GLY A 1 254 ? 211.728 79.063 39.414 1.00 41.80 ? 252 GLY A O 1 ATOM 1573 N N . VAL A 1 255 ? 209.612 79.888 39.462 1.00 34.87 ? 253 VAL A N 1 ATOM 1574 C CA . VAL A 1 255 ? 209.611 80.433 38.102 1.00 32.76 ? 253 VAL A CA 1 ATOM 1575 C C . VAL A 1 255 ? 210.415 81.709 38.157 1.00 36.13 ? 253 VAL A C 1 ATOM 1576 O O . VAL A 1 255 ? 211.288 81.924 37.322 1.00 37.09 ? 253 VAL A O 1 ATOM 1577 C CB . VAL A 1 255 ? 208.159 80.646 37.551 1.00 34.59 ? 253 VAL A CB 1 ATOM 1578 C CG1 . VAL A 1 255 ? 208.154 81.349 36.198 1.00 33.61 ? 253 VAL A CG1 1 ATOM 1579 C CG2 . VAL A 1 255 ? 207.397 79.323 37.465 1.00 33.82 ? 253 VAL A CG2 1 ATOM 1580 N N . VAL A 1 256 ? 210.156 82.541 39.167 1.00 32.76 ? 254 VAL A N 1 ATOM 1581 C CA . VAL A 1 256 ? 210.841 83.826 39.352 1.00 32.15 ? 254 VAL A CA 1 ATOM 1582 C C . VAL A 1 256 ? 212.349 83.576 39.583 1.00 37.67 ? 254 VAL A C 1 ATOM 1583 O O . VAL A 1 256 ? 213.207 84.284 39.019 1.00 36.17 ? 254 VAL A O 1 ATOM 1584 C CB . VAL A 1 256 ? 210.168 84.680 40.457 1.00 34.77 ? 254 VAL A CB 1 ATOM 1585 C CG1 . VAL A 1 256 ? 210.940 85.970 40.719 1.00 34.78 ? 254 VAL A CG1 1 ATOM 1586 C CG2 . VAL A 1 256 ? 208.725 85.009 40.089 1.00 34.22 ? 254 VAL A CG2 1 ATOM 1587 N N . ARG A 1 257 ? 212.659 82.514 40.361 1.00 34.81 ? 255 ARG A N 1 ATOM 1588 C CA . ARG A 1 257 ? 214.036 82.118 40.635 1.00 33.30 ? 255 ARG A CA 1 ATOM 1589 C C . ARG A 1 257 ? 214.702 81.670 39.318 1.00 37.82 ? 255 ARG A C 1 ATOM 1590 O O . ARG A 1 257 ? 215.793 82.155 38.995 1.00 38.87 ? 255 ARG A O 1 ATOM 1591 C CB . ARG A 1 257 ? 214.116 81.109 41.798 1.00 25.38 ? 255 ARG A CB 1 ATOM 1592 C CG . ARG A 1 257 ? 214.114 81.845 43.137 1.00 22.24 ? 255 ARG A CG 1 ATOM 1593 C CD . ARG A 1 257 ? 214.405 80.998 44.361 1.00 19.69 ? 255 ARG A CD 1 ATOM 1594 N NE . ARG A 1 257 ? 213.250 80.183 44.769 1.00 31.72 ? 255 ARG A NE 1 ATOM 1595 C CZ . ARG A 1 257 ? 212.462 80.455 45.806 1.00 55.75 ? 255 ARG A CZ 1 ATOM 1596 N NH1 . ARG A 1 257 ? 212.701 81.511 46.570 1.00 51.28 ? 255 ARG A NH1 1 ATOM 1597 N NH2 . ARG A 1 257 ? 211.432 79.669 46.090 1.00 51.75 ? 255 ARG A NH2 1 ATOM 1598 N N . ALA A 1 258 ? 213.973 80.894 38.497 1.00 32.53 ? 256 ALA A N 1 ATOM 1599 C CA . ALA A 1 258 ? 214.428 80.447 37.178 1.00 32.47 ? 256 ALA A CA 1 ATOM 1600 C C . ALA A 1 258 ? 214.744 81.614 36.259 1.00 37.19 ? 256 ALA A C 1 ATOM 1601 O O . ALA A 1 258 ? 215.679 81.509 35.467 1.00 39.57 ? 256 ALA A O 1 ATOM 1602 C CB . ALA A 1 258 ? 213.387 79.550 36.532 1.00 33.41 ? 256 ALA A CB 1 ATOM 1603 N N . LEU A 1 259 ? 213.995 82.729 36.362 1.00 31.68 ? 257 LEU A N 1 ATOM 1604 C CA . LEU A 1 259 ? 214.268 83.913 35.558 1.00 30.56 ? 257 LEU A CA 1 ATOM 1605 C C . LEU A 1 259 ? 215.465 84.661 36.103 1.00 38.84 ? 257 LEU A C 1 ATOM 1606 O O . LEU A 1 259 ? 216.153 85.328 35.333 1.00 39.92 ? 257 LEU A O 1 ATOM 1607 C CB . LEU A 1 259 ? 213.062 84.852 35.517 1.00 30.21 ? 257 LEU A CB 1 ATOM 1608 C CG . LEU A 1 259 ? 211.728 84.391 34.885 1.00 35.16 ? 257 LEU A CG 1 ATOM 1609 C CD1 . LEU A 1 259 ? 210.780 85.568 34.751 1.00 35.10 ? 257 LEU A CD1 1 ATOM 1610 C CD2 . LEU A 1 259 ? 211.907 83.783 33.480 1.00 37.59 ? 257 LEU A CD2 1 ATOM 1611 N N . LEU A 1 260 ? 215.714 84.578 37.437 1.00 37.78 ? 258 LEU A N 1 ATOM 1612 C CA . LEU A 1 260 ? 216.838 85.274 38.086 1.00 37.71 ? 258 LEU A CA 1 ATOM 1613 C C . LEU A 1 260 ? 218.191 84.579 37.849 1.00 46.72 ? 258 LEU A C 1 ATOM 1614 O O . LEU A 1 260 ? 219.235 85.220 38.026 1.00 46.13 ? 258 LEU A O 1 ATOM 1615 C CB . LEU A 1 260 ? 216.574 85.519 39.585 1.00 36.67 ? 258 LEU A CB 1 ATOM 1616 C CG . LEU A 1 260 ? 215.482 86.559 39.931 1.00 39.31 ? 258 LEU A CG 1 ATOM 1617 C CD1 . LEU A 1 260 ? 214.983 86.393 41.340 1.00 39.14 ? 258 LEU A CD1 1 ATOM 1618 C CD2 . LEU A 1 260 ? 215.908 87.979 39.648 1.00 35.80 ? 258 LEU A CD2 1 ATOM 1619 N N . GLN A 1 261 ? 218.167 83.291 37.389 1.00 46.52 ? 259 GLN A N 1 ATOM 1620 C CA . GLN A 1 261 ? 219.350 82.490 37.047 1.00 48.28 ? 259 GLN A CA 1 ATOM 1621 C C . GLN A 1 261 ? 220.046 82.992 35.754 1.00 59.89 ? 259 GLN A C 1 ATOM 1622 O O . GLN A 1 261 ? 221.140 82.519 35.410 1.00 60.29 ? 259 GLN A O 1 ATOM 1623 C CB . GLN A 1 261 ? 218.998 80.998 36.956 1.00 49.02 ? 259 GLN A CB 1 ATOM 1624 C CG . GLN A 1 261 ? 219.366 80.215 38.210 1.00 49.52 ? 259 GLN A CG 1 ATOM 1625 N N . LYS A 1 262 ? 219.407 83.974 35.060 1.00 60.07 ? 260 LYS A N 1 ATOM 1626 C CA . LYS A 1 262 ? 219.895 84.665 33.860 1.00 60.98 ? 260 LYS A CA 1 ATOM 1627 C C . LYS A 1 262 ? 219.894 86.190 34.148 1.00 67.90 ? 260 LYS A C 1 ATOM 1628 O O . LYS A 1 262 ? 219.034 86.917 33.642 1.00 66.84 ? 260 LYS A O 1 ATOM 1629 C CB . LYS A 1 262 ? 219.042 84.307 32.625 1.00 63.05 ? 260 LYS A CB 1 ATOM 1630 C CG . LYS A 1 262 ? 219.635 83.187 31.778 1.00 72.64 ? 260 LYS A CG 1 ATOM 1631 C CD . LYS A 1 262 ? 219.003 81.850 32.086 1.00 77.82 ? 260 LYS A CD 1 ATOM 1632 C CE . LYS A 1 262 ? 219.430 80.787 31.111 1.00 85.76 ? 260 LYS A CE 1 ATOM 1633 N NZ . LYS A 1 262 ? 218.767 79.488 31.417 1.00 96.67 ? 260 LYS A NZ 1 ATOM 1634 N N . PRO A 1 263 ? 220.848 86.687 34.985 1.00 67.35 ? 261 PRO A N 1 ATOM 1635 C CA . PRO A 1 263 ? 220.851 88.122 35.346 1.00 67.39 ? 261 PRO A CA 1 ATOM 1636 C C . PRO A 1 263 ? 220.905 89.115 34.185 1.00 69.71 ? 261 PRO A C 1 ATOM 1637 O O . PRO A 1 263 ? 220.483 90.268 34.347 1.00 69.29 ? 261 PRO A O 1 ATOM 1638 C CB . PRO A 1 263 ? 222.077 88.258 36.263 1.00 69.66 ? 261 PRO A CB 1 ATOM 1639 C CG . PRO A 1 263 ? 222.921 87.040 35.978 1.00 74.12 ? 261 PRO A CG 1 ATOM 1640 C CD . PRO A 1 263 ? 221.930 85.964 35.689 1.00 69.47 ? 261 PRO A CD 1 ATOM 1641 N N . SER A 1 264 ? 221.402 88.674 33.020 1.00 64.72 ? 262 SER A N 1 ATOM 1642 C CA . SER A 1 264 ? 221.470 89.520 31.829 1.00 63.65 ? 262 SER A CA 1 ATOM 1643 C C . SER A 1 264 ? 220.092 89.721 31.147 1.00 65.03 ? 262 SER A C 1 ATOM 1644 O O . SER A 1 264 ? 219.921 90.699 30.406 1.00 66.27 ? 262 SER A O 1 ATOM 1645 C CB . SER A 1 264 ? 222.514 88.990 30.856 1.00 67.25 ? 262 SER A CB 1 ATOM 1646 O OG . SER A 1 264 ? 223.814 89.236 31.368 1.00 77.45 ? 262 SER A OG 1 ATOM 1647 N N . ALA A 1 265 ? 219.110 88.813 31.424 1.00 56.78 ? 263 ALA A N 1 ATOM 1648 C CA . ALA A 1 265 ? 217.753 88.848 30.874 1.00 54.36 ? 263 ALA A CA 1 ATOM 1649 C C . ALA A 1 265 ? 216.801 89.520 31.841 1.00 53.76 ? 263 ALA A C 1 ATOM 1650 O O . ALA A 1 265 ? 216.016 88.857 32.514 1.00 53.31 ? 263 ALA A O 1 ATOM 1651 C CB . ALA A 1 265 ? 217.277 87.443 30.556 1.00 55.07 ? 263 ALA A CB 1 ATOM 1652 N N . ARG A 1 266 ? 216.883 90.845 31.914 1.00 47.72 ? 264 ARG A N 1 ATOM 1653 C CA . ARG A 1 266 ? 216.051 91.656 32.800 1.00 46.52 ? 264 ARG A CA 1 ATOM 1654 C C . ARG A 1 266 ? 214.641 91.825 32.255 1.00 46.11 ? 264 ARG A C 1 ATOM 1655 O O . ARG A 1 266 ? 213.725 92.060 33.039 1.00 45.77 ? 264 ARG A O 1 ATOM 1656 C CB . ARG A 1 266 ? 216.702 93.029 33.077 1.00 49.06 ? 264 ARG A CB 1 ATOM 1657 C CG . ARG A 1 266 ? 217.968 92.919 33.926 1.00 70.09 ? 264 ARG A CG 1 ATOM 1658 C CD . ARG A 1 266 ? 218.211 94.136 34.793 1.00 90.49 ? 264 ARG A CD 1 ATOM 1659 N NE . ARG A 1 266 ? 217.442 94.077 36.037 1.00 104.28 ? 264 ARG A NE 1 ATOM 1660 C CZ . ARG A 1 266 ? 217.550 94.959 37.027 1.00 122.37 ? 264 ARG A CZ 1 ATOM 1661 N NH1 . ARG A 1 266 ? 218.399 95.976 36.931 1.00 110.37 ? 264 ARG A NH1 1 ATOM 1662 N NH2 . ARG A 1 266 ? 216.811 94.831 38.119 1.00 111.99 ? 264 ARG A NH2 1 ATOM 1663 N N . VAL A 1 267 ? 214.473 91.755 30.916 1.00 39.10 ? 265 VAL A N 1 ATOM 1664 C CA . VAL A 1 267 ? 213.178 91.893 30.248 1.00 36.47 ? 265 VAL A CA 1 ATOM 1665 C C . VAL A 1 267 ? 212.528 90.532 30.212 1.00 35.66 ? 265 VAL A C 1 ATOM 1666 O O . VAL A 1 267 ? 213.164 89.550 29.800 1.00 33.88 ? 265 VAL A O 1 ATOM 1667 C CB . VAL A 1 267 ? 213.275 92.544 28.835 1.00 39.57 ? 265 VAL A CB 1 ATOM 1668 C CG1 . VAL A 1 267 ? 211.932 92.525 28.097 1.00 38.87 ? 265 VAL A CG1 1 ATOM 1669 C CG2 . VAL A 1 267 ? 213.802 93.963 28.924 1.00 39.00 ? 265 VAL A CG2 1 ATOM 1670 N N . ALA A 1 268 ? 211.274 90.466 30.705 1.00 31.12 ? 266 ALA A N 1 ATOM 1671 C CA . ALA A 1 268 ? 210.461 89.239 30.697 1.00 29.80 ? 266 ALA A CA 1 ATOM 1672 C C . ALA A 1 268 ? 209.186 89.482 29.851 1.00 31.99 ? 266 ALA A C 1 ATOM 1673 O O . ALA A 1 268 ? 208.447 90.439 30.084 1.00 30.72 ? 266 ALA A O 1 ATOM 1674 C CB . ALA A 1 268 ? 210.119 88.778 32.109 1.00 29.56 ? 266 ALA A CB 1 ATOM 1675 N N . VAL A 1 269 ? 208.998 88.657 28.816 1.00 27.00 ? 267 VAL A N 1 ATOM 1676 C CA . VAL A 1 269 ? 207.851 88.736 27.922 1.00 25.87 ? 267 VAL A CA 1 ATOM 1677 C C . VAL A 1 269 ? 206.811 87.703 28.370 1.00 30.64 ? 267 VAL A C 1 ATOM 1678 O O . VAL A 1 269 ? 207.077 86.492 28.335 1.00 29.25 ? 267 VAL A O 1 ATOM 1679 C CB . VAL A 1 269 ? 208.232 88.587 26.418 1.00 27.54 ? 267 VAL A CB 1 ATOM 1680 C CG1 . VAL A 1 269 ? 207.054 88.912 25.524 1.00 25.96 ? 267 VAL A CG1 1 ATOM 1681 C CG2 . VAL A 1 269 ? 209.419 89.470 26.062 1.00 26.97 ? 267 VAL A CG2 1 ATOM 1682 N N . LEU A 1 270 ? 205.617 88.186 28.777 1.00 27.63 ? 268 LEU A N 1 ATOM 1683 C CA . LEU A 1 270 ? 204.536 87.297 29.196 1.00 25.93 ? 268 LEU A CA 1 ATOM 1684 C C . LEU A 1 270 ? 203.415 87.212 28.189 1.00 26.05 ? 268 LEU A C 1 ATOM 1685 O O . LEU A 1 270 ? 202.942 88.238 27.690 1.00 25.23 ? 268 LEU A O 1 ATOM 1686 C CB . LEU A 1 270 ? 203.941 87.670 30.580 1.00 25.97 ? 268 LEU A CB 1 ATOM 1687 C CG . LEU A 1 270 ? 204.847 88.257 31.664 1.00 30.34 ? 268 LEU A CG 1 ATOM 1688 C CD1 . LEU A 1 270 ? 204.047 88.576 32.934 1.00 29.63 ? 268 LEU A CD1 1 ATOM 1689 C CD2 . LEU A 1 270 ? 206.027 87.340 31.980 1.00 31.01 ? 268 LEU A CD2 1 ATOM 1690 N N . PHE A 1 271 ? 202.974 85.977 27.927 1.00 20.76 ? 269 PHE A N 1 ATOM 1691 C CA . PHE A 1 271 ? 201.769 85.624 27.173 1.00 20.65 ? 269 PHE A CA 1 ATOM 1692 C C . PHE A 1 271 ? 201.024 84.747 28.183 1.00 26.31 ? 269 PHE A C 1 ATOM 1693 O O . PHE A 1 271 ? 201.019 83.505 28.116 1.00 24.64 ? 269 PHE A O 1 ATOM 1694 C CB . PHE A 1 271 ? 202.053 84.864 25.867 1.00 21.91 ? 269 PHE A CB 1 ATOM 1695 C CG . PHE A 1 271 ? 201.463 85.549 24.676 1.00 22.68 ? 269 PHE A CG 1 ATOM 1696 C CD1 . PHE A 1 271 ? 200.085 85.565 24.474 1.00 24.21 ? 269 PHE A CD1 1 ATOM 1697 C CD2 . PHE A 1 271 ? 202.274 86.254 23.788 1.00 24.80 ? 269 PHE A CD2 1 ATOM 1698 C CE1 . PHE A 1 271 ? 199.531 86.245 23.387 1.00 24.14 ? 269 PHE A CE1 1 ATOM 1699 C CE2 . PHE A 1 271 ? 201.718 86.925 22.692 1.00 26.53 ? 269 PHE A CE2 1 ATOM 1700 C CZ . PHE A 1 271 ? 200.350 86.905 22.494 1.00 23.74 ? 269 PHE A CZ 1 ATOM 1701 N N . THR A 1 272 ? 200.508 85.422 29.207 1.00 24.62 ? 270 THR A N 1 ATOM 1702 C CA . THR A 1 272 ? 199.883 84.773 30.355 1.00 24.50 ? 270 THR A CA 1 ATOM 1703 C C . THR A 1 272 ? 198.449 85.201 30.576 1.00 26.62 ? 270 THR A C 1 ATOM 1704 O O . THR A 1 272 ? 198.061 86.336 30.243 1.00 25.44 ? 270 THR A O 1 ATOM 1705 C CB . THR A 1 272 ? 200.728 85.000 31.640 1.00 25.18 ? 270 THR A CB 1 ATOM 1706 O OG1 . THR A 1 272 ? 200.888 86.397 31.845 1.00 24.74 ? 270 THR A OG1 1 ATOM 1707 C CG2 . THR A 1 272 ? 202.111 84.392 31.553 1.00 24.65 ? 270 THR A CG2 1 ATOM 1708 N N . ARG A 1 273 ? 197.674 84.281 31.177 1.00 21.35 ? 271 ARG A N 1 ATOM 1709 C CA . ARG A 1 273 ? 196.315 84.519 31.617 1.00 21.25 ? 271 ARG A CA 1 ATOM 1710 C C . ARG A 1 273 ? 196.444 85.535 32.787 1.00 26.58 ? 271 ARG A C 1 ATOM 1711 O O . ARG A 1 273 ? 197.514 85.604 33.437 1.00 27.74 ? 271 ARG A O 1 ATOM 1712 C CB . ARG A 1 273 ? 195.688 83.190 32.108 1.00 21.16 ? 271 ARG A CB 1 ATOM 1713 C CG . ARG A 1 273 ? 195.464 82.141 30.991 1.00 25.80 ? 271 ARG A CG 1 ATOM 1714 C CD . ARG A 1 273 ? 195.247 80.751 31.541 1.00 29.47 ? 271 ARG A CD 1 ATOM 1715 N NE . ARG A 1 273 ? 193.968 80.625 32.239 1.00 34.94 ? 271 ARG A NE 1 ATOM 1716 C CZ . ARG A 1 273 ? 192.874 80.084 31.706 1.00 51.35 ? 271 ARG A CZ 1 ATOM 1717 N NH1 . ARG A 1 273 ? 191.750 80.017 32.409 1.00 29.17 ? 271 ARG A NH1 1 ATOM 1718 N NH2 . ARG A 1 273 ? 192.883 79.649 30.450 1.00 46.65 ? 271 ARG A NH2 1 ATOM 1719 N N . SER A 1 274 ? 195.400 86.342 33.023 1.00 21.12 ? 272 SER A N 1 ATOM 1720 C CA . SER A 1 274 ? 195.395 87.360 34.087 1.00 20.87 ? 272 SER A CA 1 ATOM 1721 C C . SER A 1 274 ? 195.895 86.843 35.441 1.00 27.61 ? 272 SER A C 1 ATOM 1722 O O . SER A 1 274 ? 196.827 87.410 36.004 1.00 27.34 ? 272 SER A O 1 ATOM 1723 C CB . SER A 1 274 ? 194.005 87.955 34.257 1.00 23.24 ? 272 SER A CB 1 ATOM 1724 O OG . SER A 1 274 ? 192.993 86.986 34.030 1.00 31.43 ? 272 SER A OG 1 ATOM 1725 N N . GLU A 1 275 ? 195.298 85.741 35.930 1.00 25.02 ? 273 GLU A N 1 ATOM 1726 C CA . GLU A 1 275 ? 195.577 85.105 37.209 1.00 25.02 ? 273 GLU A CA 1 ATOM 1727 C C . GLU A 1 275 ? 197.031 84.647 37.325 1.00 31.95 ? 273 GLU A C 1 ATOM 1728 O O . GLU A 1 275 ? 197.607 84.714 38.411 1.00 33.04 ? 273 GLU A O 1 ATOM 1729 C CB . GLU A 1 275 ? 194.613 83.938 37.429 1.00 26.65 ? 273 GLU A CB 1 ATOM 1730 C CG . GLU A 1 275 ? 194.768 82.792 36.423 1.00 41.83 ? 273 GLU A CG 1 ATOM 1731 C CD . GLU A 1 275 ? 193.828 82.759 35.228 1.00 65.89 ? 273 GLU A CD 1 ATOM 1732 O OE1 . GLU A 1 275 ? 193.425 81.636 34.841 1.00 66.72 ? 273 GLU A OE1 1 ATOM 1733 O OE2 . GLU A 1 275 ? 193.490 83.840 34.684 1.00 47.73 ? 273 GLU A OE2 1 ATOM 1734 N N . ASP A 1 276 ? 197.623 84.186 36.212 1.00 27.36 ? 274 ASP A N 1 ATOM 1735 C CA . ASP A 1 276 ? 199.009 83.749 36.195 1.00 26.01 ? 274 ASP A CA 1 ATOM 1736 C C . ASP A 1 276 ? 199.890 84.963 36.201 1.00 28.25 ? 274 ASP A C 1 ATOM 1737 O O . ASP A 1 276 ? 200.892 84.946 36.892 1.00 28.22 ? 274 ASP A O 1 ATOM 1738 C CB . ASP A 1 276 ? 199.282 82.836 34.996 1.00 28.08 ? 274 ASP A CB 1 ATOM 1739 C CG . ASP A 1 276 ? 198.425 81.575 34.994 1.00 39.57 ? 274 ASP A CG 1 ATOM 1740 O OD1 . ASP A 1 276 ? 197.973 81.165 36.080 1.00 42.60 ? 274 ASP A OD1 1 ATOM 1741 O OD2 . ASP A 1 276 ? 198.239 80.979 33.904 1.00 42.15 ? 274 ASP A OD2 1 ATOM 1742 N N . ALA A 1 277 ? 199.505 86.040 35.471 1.00 24.24 ? 275 ALA A N 1 ATOM 1743 C CA . ALA A 1 277 ? 200.232 87.320 35.473 1.00 22.93 ? 275 ALA A CA 1 ATOM 1744 C C . ALA A 1 277 ? 200.208 87.903 36.913 1.00 27.74 ? 275 ALA A C 1 ATOM 1745 O O . ALA A 1 277 ? 201.220 88.384 37.382 1.00 28.09 ? 275 ALA A O 1 ATOM 1746 C CB . ALA A 1 277 ? 199.610 88.304 34.471 1.00 22.69 ? 275 ALA A CB 1 ATOM 1747 N N . ARG A 1 278 ? 199.077 87.780 37.620 1.00 25.32 ? 276 ARG A N 1 ATOM 1748 C CA . ARG A 1 278 ? 198.873 88.233 38.997 1.00 25.34 ? 276 ARG A CA 1 ATOM 1749 C C . ARG A 1 278 ? 199.802 87.456 39.975 1.00 29.42 ? 276 ARG A C 1 ATOM 1750 O O . ARG A 1 278 ? 200.555 88.051 40.746 1.00 30.27 ? 276 ARG A O 1 ATOM 1751 C CB . ARG A 1 278 ? 197.385 88.042 39.390 1.00 24.38 ? 276 ARG A CB 1 ATOM 1752 C CG . ARG A 1 278 ? 197.050 88.636 40.770 1.00 36.39 ? 276 ARG A CG 1 ATOM 1753 C CD . ARG A 1 278 ? 195.605 88.508 41.206 1.00 35.99 ? 276 ARG A CD 1 ATOM 1754 N NE . ARG A 1 278 ? 195.026 87.205 40.883 1.00 52.33 ? 276 ARG A NE 1 ATOM 1755 C CZ . ARG A 1 278 ? 195.157 86.112 41.626 1.00 76.51 ? 276 ARG A CZ 1 ATOM 1756 N NH1 . ARG A 1 278 ? 195.844 86.150 42.763 1.00 72.75 ? 276 ARG A NH1 1 ATOM 1757 N NH2 . ARG A 1 278 ? 194.605 84.969 41.237 1.00 61.26 ? 276 ARG A NH2 1 ATOM 1758 N N . GLU A 1 279 ? 199.741 86.146 39.914 1.00 25.92 ? 277 GLU A N 1 ATOM 1759 C CA . GLU A 1 279 ? 200.509 85.235 40.735 1.00 26.90 ? 277 GLU A CA 1 ATOM 1760 C C . GLU A 1 279 ? 202.021 85.349 40.549 1.00 36.10 ? 277 GLU A C 1 ATOM 1761 O O . GLU A 1 279 ? 202.782 85.211 41.519 1.00 37.06 ? 277 GLU A O 1 ATOM 1762 C CB . GLU A 1 279 ? 200.023 83.808 40.512 1.00 27.44 ? 277 GLU A CB 1 ATOM 1763 C CG . GLU A 1 279 ? 198.709 83.538 41.221 1.00 34.89 ? 277 GLU A CG 1 ATOM 1764 C CD . GLU A 1 279 ? 198.775 83.709 42.725 1.00 65.88 ? 277 GLU A CD 1 ATOM 1765 O OE1 . GLU A 1 279 ? 198.084 84.612 43.252 1.00 54.05 ? 277 GLU A OE1 1 ATOM 1766 O OE2 . GLU A 1 279 ? 199.543 82.962 43.375 1.00 70.98 ? 277 GLU A OE2 1 ATOM 1767 N N . LEU A 1 280 ? 202.445 85.660 39.329 1.00 34.25 ? 278 LEU A N 1 ATOM 1768 C CA . LEU A 1 280 ? 203.844 85.854 38.992 1.00 35.02 ? 278 LEU A CA 1 ATOM 1769 C C . LEU A 1 280 ? 204.328 87.195 39.558 1.00 36.48 ? 278 LEU A C 1 ATOM 1770 O O . LEU A 1 280 ? 205.428 87.274 40.090 1.00 34.92 ? 278 LEU A O 1 ATOM 1771 C CB . LEU A 1 280 ? 204.000 85.803 37.462 1.00 36.25 ? 278 LEU A CB 1 ATOM 1772 C CG . LEU A 1 280 ? 205.417 85.706 36.941 1.00 43.60 ? 278 LEU A CG 1 ATOM 1773 C CD1 . LEU A 1 280 ? 206.037 84.317 37.244 1.00 43.91 ? 278 LEU A CD1 1 ATOM 1774 C CD2 . LEU A 1 280 ? 205.439 85.975 35.471 1.00 50.20 ? 278 LEU A CD2 1 ATOM 1775 N N . LEU A 1 281 ? 203.495 88.233 39.467 1.00 33.36 ? 279 LEU A N 1 ATOM 1776 C CA . LEU A 1 281 ? 203.828 89.541 39.997 1.00 33.94 ? 279 LEU A CA 1 ATOM 1777 C C . LEU A 1 281 ? 203.938 89.488 41.494 1.00 38.74 ? 279 LEU A C 1 ATOM 1778 O O . LEU A 1 281 ? 204.870 90.075 42.057 1.00 39.13 ? 279 LEU A O 1 ATOM 1779 C CB . LEU A 1 281 ? 202.789 90.600 39.565 1.00 34.65 ? 279 LEU A CB 1 ATOM 1780 C CG . LEU A 1 281 ? 203.175 91.488 38.359 1.00 39.72 ? 279 LEU A CG 1 ATOM 1781 C CD1 . LEU A 1 281 ? 204.504 92.145 38.579 1.00 39.44 ? 279 LEU A CD1 1 ATOM 1782 C CD2 . LEU A 1 281 ? 203.300 90.669 37.092 1.00 43.88 ? 279 LEU A CD2 1 ATOM 1783 N N . ALA A 1 282 ? 202.981 88.773 42.145 1.00 34.09 ? 280 ALA A N 1 ATOM 1784 C CA . ALA A 1 282 ? 202.934 88.556 43.589 1.00 32.21 ? 280 ALA A CA 1 ATOM 1785 C C . ALA A 1 282 ? 204.173 87.796 44.048 1.00 36.32 ? 280 ALA A C 1 ATOM 1786 O O . ALA A 1 282 ? 204.675 88.073 45.131 1.00 36.88 ? 280 ALA A O 1 ATOM 1787 C CB . ALA A 1 282 ? 201.686 87.780 43.958 1.00 32.54 ? 280 ALA A CB 1 ATOM 1788 N N . ALA A 1 283 ? 204.688 86.846 43.240 1.00 32.37 ? 281 ALA A N 1 ATOM 1789 C CA . ALA A 1 283 ? 205.896 86.141 43.663 1.00 31.78 ? 281 ALA A CA 1 ATOM 1790 C C . ALA A 1 283 ? 207.129 87.045 43.523 1.00 34.99 ? 281 ALA A C 1 ATOM 1791 O O . ALA A 1 283 ? 207.967 87.026 44.413 1.00 36.03 ? 281 ALA A O 1 ATOM 1792 C CB . ALA A 1 283 ? 206.066 84.831 42.924 1.00 32.42 ? 281 ALA A CB 1 ATOM 1793 N N . SER A 1 284 ? 207.190 87.897 42.482 1.00 30.17 ? 282 SER A N 1 ATOM 1794 C CA . SER A 1 284 ? 208.279 88.876 42.269 1.00 29.52 ? 282 SER A CA 1 ATOM 1795 C C . SER A 1 284 ? 208.337 89.835 43.458 1.00 33.42 ? 282 SER A C 1 ATOM 1796 O O . SER A 1 284 ? 209.430 90.136 43.947 1.00 33.02 ? 282 SER A O 1 ATOM 1797 C CB . SER A 1 284 ? 208.070 89.684 40.986 1.00 30.36 ? 282 SER A CB 1 ATOM 1798 O OG . SER A 1 284 ? 207.840 88.844 39.870 1.00 37.91 ? 282 SER A OG 1 ATOM 1799 N N . GLN A 1 285 ? 207.151 90.298 43.920 1.00 29.97 ? 283 GLN A N 1 ATOM 1800 C CA . GLN A 1 285 ? 206.979 91.186 45.070 1.00 29.78 ? 283 GLN A CA 1 ATOM 1801 C C . GLN A 1 285 ? 207.527 90.507 46.348 1.00 35.79 ? 283 GLN A C 1 ATOM 1802 O O . GLN A 1 285 ? 208.391 91.073 47.021 1.00 37.96 ? 283 GLN A O 1 ATOM 1803 C CB . GLN A 1 285 ? 205.499 91.589 45.206 1.00 30.76 ? 283 GLN A CB 1 ATOM 1804 C CG . GLN A 1 285 ? 205.179 92.725 46.183 1.00 33.74 ? 283 GLN A CG 1 ATOM 1805 C CD . GLN A 1 285 ? 205.876 94.004 45.861 1.00 53.89 ? 283 GLN A CD 1 ATOM 1806 O OE1 . GLN A 1 285 ? 205.422 94.789 45.030 1.00 54.75 ? 283 GLN A OE1 1 ATOM 1807 N NE2 . GLN A 1 285 ? 207.015 94.228 46.500 1.00 50.67 ? 283 GLN A NE2 1 ATOM 1808 N N . ARG A 1 286 ? 207.128 89.254 46.601 1.00 30.48 ? 284 ARG A N 1 ATOM 1809 C CA . ARG A 1 286 ? 207.598 88.495 47.752 1.00 29.45 ? 284 ARG A CA 1 ATOM 1810 C C . ARG A 1 286 ? 209.100 88.213 47.752 1.00 36.38 ? 284 ARG A C 1 ATOM 1811 O O . ARG A 1 286 ? 209.654 87.952 48.825 1.00 39.58 ? 284 ARG A O 1 ATOM 1812 C CB . ARG A 1 286 ? 206.808 87.197 47.917 1.00 25.62 ? 284 ARG A CB 1 ATOM 1813 C CG . ARG A 1 286 ? 205.375 87.467 48.321 1.00 33.77 ? 284 ARG A CG 1 ATOM 1814 C CD . ARG A 1 286 ? 204.516 86.240 48.542 1.00 39.67 ? 284 ARG A CD 1 ATOM 1815 N NE . ARG A 1 286 ? 204.713 85.167 47.563 1.00 37.59 ? 284 ARG A NE 1 ATOM 1816 C CZ . ARG A 1 286 ? 203.780 84.743 46.717 1.00 44.78 ? 284 ARG A CZ 1 ATOM 1817 N NH1 . ARG A 1 286 ? 204.026 83.723 45.906 1.00 18.57 ? 284 ARG A NH1 1 ATOM 1818 N NH2 . ARG A 1 286 ? 202.581 85.312 46.699 1.00 36.81 ? 284 ARG A NH2 1 ATOM 1819 N N . LEU A 1 287 ? 209.764 88.260 46.586 1.00 30.77 ? 285 LEU A N 1 ATOM 1820 C CA . LEU A 1 287 ? 211.195 87.974 46.475 1.00 28.75 ? 285 LEU A CA 1 ATOM 1821 C C . LEU A 1 287 ? 211.997 89.244 46.166 1.00 34.11 ? 285 LEU A C 1 ATOM 1822 O O . LEU A 1 287 ? 213.189 89.140 45.901 1.00 35.49 ? 285 LEU A O 1 ATOM 1823 C CB . LEU A 1 287 ? 211.448 86.925 45.379 1.00 28.04 ? 285 LEU A CB 1 ATOM 1824 C CG . LEU A 1 287 ? 210.720 85.582 45.468 1.00 33.42 ? 285 LEU A CG 1 ATOM 1825 C CD1 . LEU A 1 287 ? 210.829 84.825 44.185 1.00 33.29 ? 285 LEU A CD1 1 ATOM 1826 C CD2 . LEU A 1 287 ? 211.255 84.700 46.568 1.00 36.14 ? 285 LEU A CD2 1 ATOM 1827 N N . ASN A 1 288 ? 211.380 90.440 46.195 1.00 30.03 ? 286 ASN A N 1 ATOM 1828 C CA . ASN A 1 288 ? 212.079 91.683 45.844 1.00 30.83 ? 286 ASN A CA 1 ATOM 1829 C C . ASN A 1 288 ? 212.798 91.480 44.487 1.00 36.84 ? 286 ASN A C 1 ATOM 1830 O O . ASN A 1 288 ? 213.937 91.923 44.304 1.00 38.23 ? 286 ASN A O 1 ATOM 1831 C CB . ASN A 1 288 ? 213.054 92.151 46.975 1.00 33.00 ? 286 ASN A CB 1 ATOM 1832 C CG . ASN A 1 288 ? 213.644 93.544 46.821 1.00 60.61 ? 286 ASN A CG 1 ATOM 1833 O OD1 . ASN A 1 288 ? 212.942 94.501 46.534 1.00 49.72 ? 286 ASN A OD1 1 ATOM 1834 N ND2 . ASN A 1 288 ? 214.953 93.677 47.011 1.00 73.65 ? 286 ASN A ND2 1 ATOM 1835 N N . ALA A 1 289 ? 212.150 90.751 43.556 1.00 32.95 ? 287 ALA A N 1 ATOM 1836 C CA . ALA A 1 289 ? 212.735 90.479 42.244 1.00 32.97 ? 287 ALA A CA 1 ATOM 1837 C C . ALA A 1 289 ? 212.341 91.585 41.272 1.00 39.79 ? 287 ALA A C 1 ATOM 1838 O O . ALA A 1 289 ? 211.213 92.079 41.341 1.00 40.28 ? 287 ALA A O 1 ATOM 1839 C CB . ALA A 1 289 ? 212.300 89.118 41.739 1.00 33.40 ? 287 ALA A CB 1 ATOM 1840 N N . SER A 1 290 ? 213.282 92.029 40.419 1.00 37.70 ? 288 SER A N 1 ATOM 1841 C CA . SER A 1 290 ? 213.020 93.137 39.489 1.00 37.90 ? 288 SER A CA 1 ATOM 1842 C C . SER A 1 290 ? 213.157 92.777 38.014 1.00 41.29 ? 288 SER A C 1 ATOM 1843 O O . SER A 1 290 ? 214.255 92.431 37.539 1.00 41.04 ? 288 SER A O 1 ATOM 1844 C CB . SER A 1 290 ? 213.878 94.355 39.816 1.00 42.52 ? 288 SER A CB 1 ATOM 1845 O OG . SER A 1 290 ? 213.643 95.394 38.881 1.00 58.85 ? 288 SER A OG 1 ATOM 1846 N N . PHE A 1 291 ? 212.020 92.889 37.294 1.00 35.29 ? 289 PHE A N 1 ATOM 1847 C CA . PHE A 1 291 ? 211.949 92.642 35.874 1.00 33.61 ? 289 PHE A CA 1 ATOM 1848 C C . PHE A 1 291 ? 211.197 93.742 35.180 1.00 37.03 ? 289 PHE A C 1 ATOM 1849 O O . PHE A 1 291 ? 210.280 94.324 35.750 1.00 36.55 ? 289 PHE A O 1 ATOM 1850 C CB . PHE A 1 291 ? 211.238 91.317 35.584 1.00 34.91 ? 289 PHE A CB 1 ATOM 1851 C CG . PHE A 1 291 ? 211.922 90.107 36.148 1.00 36.48 ? 289 PHE A CG 1 ATOM 1852 C CD1 . PHE A 1 291 ? 213.032 89.554 35.511 1.00 38.80 ? 289 PHE A CD1 1 ATOM 1853 C CD2 . PHE A 1 291 ? 211.448 89.501 37.309 1.00 38.84 ? 289 PHE A CD2 1 ATOM 1854 C CE1 . PHE A 1 291 ? 213.681 88.439 36.044 1.00 39.57 ? 289 PHE A CE1 1 ATOM 1855 C CE2 . PHE A 1 291 ? 212.081 88.371 37.830 1.00 41.73 ? 289 PHE A CE2 1 ATOM 1856 C CZ . PHE A 1 291 ? 213.196 87.845 37.193 1.00 39.44 ? 289 PHE A CZ 1 ATOM 1857 N N . THR A 1 292 ? 211.568 93.995 33.927 1.00 33.44 ? 290 THR A N 1 ATOM 1858 C CA . THR A 1 292 ? 210.852 94.873 33.021 1.00 33.05 ? 290 THR A CA 1 ATOM 1859 C C . THR A 1 292 ? 209.879 93.894 32.309 1.00 33.86 ? 290 THR A C 1 ATOM 1860 O O . THR A 1 292 ? 210.315 92.983 31.590 1.00 31.82 ? 290 THR A O 1 ATOM 1861 C CB . THR A 1 292 ? 211.822 95.554 32.048 1.00 42.85 ? 290 THR A CB 1 ATOM 1862 O OG1 . THR A 1 292 ? 212.858 96.187 32.793 1.00 44.01 ? 290 THR A OG1 1 ATOM 1863 C CG2 . THR A 1 292 ? 211.131 96.560 31.147 1.00 40.52 ? 290 THR A CG2 1 ATOM 1864 N N . TRP A 1 293 ? 208.584 94.029 32.594 1.00 29.24 ? 291 TRP A N 1 ATOM 1865 C CA . TRP A 1 293 ? 207.569 93.158 32.017 1.00 28.01 ? 291 TRP A CA 1 ATOM 1866 C C . TRP A 1 293 ? 207.020 93.728 30.728 1.00 31.71 ? 291 TRP A C 1 ATOM 1867 O O . TRP A 1 293 ? 206.632 94.902 30.664 1.00 31.15 ? 291 TRP A O 1 ATOM 1868 C CB . TRP A 1 293 ? 206.406 92.935 32.977 1.00 26.14 ? 291 TRP A CB 1 ATOM 1869 C CG . TRP A 1 293 ? 206.807 92.592 34.375 1.00 27.11 ? 291 TRP A CG 1 ATOM 1870 C CD1 . TRP A 1 293 ? 206.862 93.437 35.447 1.00 30.11 ? 291 TRP A CD1 1 ATOM 1871 C CD2 . TRP A 1 293 ? 207.116 91.287 34.876 1.00 26.68 ? 291 TRP A CD2 1 ATOM 1872 N NE1 . TRP A 1 293 ? 207.220 92.742 36.580 1.00 29.58 ? 291 TRP A NE1 1 ATOM 1873 C CE2 . TRP A 1 293 ? 207.353 91.416 36.266 1.00 30.48 ? 291 TRP A CE2 1 ATOM 1874 C CE3 . TRP A 1 293 ? 207.216 90.016 34.281 1.00 27.75 ? 291 TRP A CE3 1 ATOM 1875 C CZ2 . TRP A 1 293 ? 207.703 90.330 37.068 1.00 29.76 ? 291 TRP A CZ2 1 ATOM 1876 C CZ3 . TRP A 1 293 ? 207.537 88.930 35.082 1.00 29.59 ? 291 TRP A CZ3 1 ATOM 1877 C CH2 . TRP A 1 293 ? 207.779 89.090 36.458 1.00 30.51 ? 291 TRP A CH2 1 ATOM 1878 N N . VAL A 1 294 ? 206.977 92.875 29.707 1.00 26.95 ? 292 VAL A N 1 ATOM 1879 C CA . VAL A 1 294 ? 206.347 93.150 28.432 1.00 26.61 ? 292 VAL A CA 1 ATOM 1880 C C . VAL A 1 294 ? 205.268 92.086 28.367 1.00 30.91 ? 292 VAL A C 1 ATOM 1881 O O . VAL A 1 294 ? 205.586 90.897 28.380 1.00 29.47 ? 292 VAL A O 1 ATOM 1882 C CB . VAL A 1 294 ? 207.308 93.135 27.221 1.00 29.52 ? 292 VAL A CB 1 ATOM 1883 C CG1 . VAL A 1 294 ? 206.577 93.599 25.948 1.00 28.13 ? 292 VAL A CG1 1 ATOM 1884 C CG2 . VAL A 1 294 ? 208.538 94.004 27.500 1.00 28.99 ? 292 VAL A CG2 1 ATOM 1885 N N . ALA A 1 295 ? 203.998 92.502 28.464 1.00 28.55 ? 293 ALA A N 1 ATOM 1886 C CA . ALA A 1 295 ? 202.918 91.525 28.533 1.00 28.10 ? 293 ALA A CA 1 ATOM 1887 C C . ALA A 1 295 ? 201.760 91.762 27.571 1.00 32.02 ? 293 ALA A C 1 ATOM 1888 O O . ALA A 1 295 ? 201.441 92.892 27.181 1.00 31.07 ? 293 ALA A O 1 ATOM 1889 C CB . ALA A 1 295 ? 202.400 91.415 29.964 1.00 28.41 ? 293 ALA A CB 1 ATOM 1890 N N . SER A 1 296 ? 201.098 90.643 27.249 1.00 27.81 ? 294 SER A N 1 ATOM 1891 C CA . SER A 1 296 ? 199.954 90.522 26.369 1.00 25.25 ? 294 SER A CA 1 ATOM 1892 C C . SER A 1 296 ? 198.658 90.974 27.053 1.00 27.39 ? 294 SER A C 1 ATOM 1893 O O . SER A 1 296 ? 198.664 91.362 28.218 1.00 25.51 ? 294 SER A O 1 ATOM 1894 C CB . SER A 1 296 ? 199.861 89.085 25.879 1.00 25.45 ? 294 SER A CB 1 ATOM 1895 O OG . SER A 1 296 ? 199.765 88.222 26.995 1.00 30.29 ? 294 SER A OG 1 ATOM 1896 N N . ASP A 1 297 ? 197.551 90.914 26.313 1.00 25.62 ? 295 ASP A N 1 ATOM 1897 C CA . ASP A 1 297 ? 196.196 91.329 26.696 1.00 25.03 ? 295 ASP A CA 1 ATOM 1898 C C . ASP A 1 297 ? 195.635 90.626 27.939 1.00 29.31 ? 295 ASP A C 1 ATOM 1899 O O . ASP A 1 297 ? 194.823 91.230 28.641 1.00 29.12 ? 295 ASP A O 1 ATOM 1900 C CB . ASP A 1 297 ? 195.247 91.208 25.496 1.00 26.50 ? 295 ASP A CB 1 ATOM 1901 C CG . ASP A 1 297 ? 194.819 89.795 25.143 1.00 33.50 ? 295 ASP A CG 1 ATOM 1902 O OD1 . ASP A 1 297 ? 195.702 88.978 24.740 1.00 33.99 ? 295 ASP A OD1 1 ATOM 1903 O OD2 . ASP A 1 297 ? 193.602 89.535 25.152 1.00 30.35 ? 295 ASP A OD2 1 ATOM 1904 N N . GLY A 1 298 ? 196.089 89.395 28.214 1.00 26.91 ? 296 GLY A N 1 ATOM 1905 C CA . GLY A 1 298 ? 195.720 88.622 29.403 1.00 25.80 ? 296 GLY A CA 1 ATOM 1906 C C . GLY A 1 298 ? 195.837 89.492 30.638 1.00 29.56 ? 296 GLY A C 1 ATOM 1907 O O . GLY A 1 298 ? 194.868 89.673 31.372 1.00 29.12 ? 296 GLY A O 1 ATOM 1908 N N . TRP A 1 299 ? 197.005 90.115 30.817 1.00 27.01 ? 297 TRP A N 1 ATOM 1909 C CA . TRP A 1 299 ? 197.276 91.093 31.869 1.00 26.15 ? 297 TRP A CA 1 ATOM 1910 C C . TRP A 1 299 ? 196.578 92.400 31.453 1.00 29.76 ? 297 TRP A C 1 ATOM 1911 O O . TRP A 1 299 ? 195.744 92.895 32.223 1.00 31.08 ? 297 TRP A O 1 ATOM 1912 C CB . TRP A 1 299 ? 198.801 91.277 32.034 1.00 25.06 ? 297 TRP A CB 1 ATOM 1913 C CG . TRP A 1 299 ? 199.265 92.377 32.949 1.00 26.32 ? 297 TRP A CG 1 ATOM 1914 C CD1 . TRP A 1 299 ? 198.567 93.489 33.345 1.00 29.02 ? 297 TRP A CD1 1 ATOM 1915 C CD2 . TRP A 1 299 ? 200.587 92.535 33.455 1.00 26.74 ? 297 TRP A CD2 1 ATOM 1916 N NE1 . TRP A 1 299 ? 199.366 94.310 34.096 1.00 28.81 ? 297 TRP A NE1 1 ATOM 1917 C CE2 . TRP A 1 299 ? 200.621 93.760 34.171 1.00 30.79 ? 297 TRP A CE2 1 ATOM 1918 C CE3 . TRP A 1 299 ? 201.753 91.751 33.394 1.00 28.61 ? 297 TRP A CE3 1 ATOM 1919 C CZ2 . TRP A 1 299 ? 201.786 94.231 34.803 1.00 29.96 ? 297 TRP A CZ2 1 ATOM 1920 C CZ3 . TRP A 1 299 ? 202.922 92.240 33.981 1.00 30.74 ? 297 TRP A CZ3 1 ATOM 1921 C CH2 . TRP A 1 299 ? 202.925 93.452 34.700 1.00 31.19 ? 297 TRP A CH2 1 ATOM 1922 N N . GLY A 1 300 ? 196.912 92.919 30.253 1.00 23.71 ? 298 GLY A N 1 ATOM 1923 C CA . GLY A 1 300 ? 196.337 94.133 29.674 1.00 22.88 ? 298 GLY A CA 1 ATOM 1924 C C . GLY A 1 300 ? 196.409 95.333 30.593 1.00 26.92 ? 298 GLY A C 1 ATOM 1925 O O . GLY A 1 300 ? 197.462 95.621 31.133 1.00 26.21 ? 298 GLY A O 1 ATOM 1926 N N . ALA A 1 301 ? 195.286 96.007 30.821 1.00 25.16 ? 299 ALA A N 1 ATOM 1927 C CA . ALA A 1 301 ? 195.207 97.185 31.701 1.00 24.73 ? 299 ALA A CA 1 ATOM 1928 C C . ALA A 1 301 ? 194.370 96.889 32.955 1.00 28.88 ? 299 ALA A C 1 ATOM 1929 O O . ALA A 1 301 ? 193.776 97.794 33.533 1.00 28.81 ? 299 ALA A O 1 ATOM 1930 C CB . ALA A 1 301 ? 194.641 98.387 30.935 1.00 24.96 ? 299 ALA A CB 1 ATOM 1931 N N . LEU A 1 302 ? 194.332 95.618 33.381 1.00 26.11 ? 300 LEU A N 1 ATOM 1932 C CA . LEU A 1 302 ? 193.586 95.197 34.571 1.00 25.35 ? 300 LEU A CA 1 ATOM 1933 C C . LEU A 1 302 ? 194.260 95.665 35.816 1.00 30.74 ? 300 LEU A C 1 ATOM 1934 O O . LEU A 1 302 ? 195.440 95.354 36.024 1.00 30.84 ? 300 LEU A O 1 ATOM 1935 C CB . LEU A 1 302 ? 193.493 93.657 34.679 1.00 24.69 ? 300 LEU A CB 1 ATOM 1936 C CG . LEU A 1 302 ? 192.496 92.877 33.837 1.00 26.41 ? 300 LEU A CG 1 ATOM 1937 C CD1 . LEU A 1 302 ? 192.589 91.424 34.189 1.00 24.89 ? 300 LEU A CD1 1 ATOM 1938 C CD2 . LEU A 1 302 ? 191.055 93.365 34.044 1.00 26.12 ? 300 LEU A CD2 1 ATOM 1939 N N . GLU A 1 303 ? 193.490 96.307 36.706 1.00 27.79 ? 301 GLU A N 1 ATOM 1940 C CA . GLU A 1 303 ? 194.016 96.705 38.009 1.00 27.02 ? 301 GLU A CA 1 ATOM 1941 C C . GLU A 1 303 ? 194.106 95.481 38.984 1.00 32.31 ? 301 GLU A C 1 ATOM 1942 O O . GLU A 1 303 ? 194.935 95.481 39.895 1.00 33.66 ? 301 GLU A O 1 ATOM 1943 C CB . GLU A 1 303 ? 193.216 97.873 38.600 1.00 28.17 ? 301 GLU A CB 1 ATOM 1944 C CG . GLU A 1 303 ? 193.456 99.217 37.919 1.00 43.65 ? 301 GLU A CG 1 ATOM 1945 C CD . GLU A 1 303 ? 194.801 99.912 38.109 1.00 83.35 ? 301 GLU A CD 1 ATOM 1946 O OE1 . GLU A 1 303 ? 195.672 99.384 38.845 1.00 80.37 ? 301 GLU A OE1 1 ATOM 1947 O OE2 . GLU A 1 303 ? 194.974 101.008 37.521 1.00 80.72 ? 301 GLU A OE2 1 ATOM 1948 N N . GLU A 1 304 ? 193.309 94.422 38.773 1.00 28.21 ? 302 GLU A N 1 ATOM 1949 C CA . GLU A 1 304 ? 193.370 93.279 39.695 1.00 28.74 ? 302 GLU A CA 1 ATOM 1950 C C . GLU A 1 304 ? 194.659 92.447 39.533 1.00 35.36 ? 302 GLU A C 1 ATOM 1951 O O . GLU A 1 304 ? 195.051 91.748 40.470 1.00 37.36 ? 302 GLU A O 1 ATOM 1952 C CB . GLU A 1 304 ? 192.099 92.392 39.668 1.00 29.86 ? 302 GLU A CB 1 ATOM 1953 C CG . GLU A 1 304 ? 191.385 92.279 38.333 1.00 44.49 ? 302 GLU A CG 1 ATOM 1954 C CD . GLU A 1 304 ? 190.244 93.266 38.139 1.00 76.59 ? 302 GLU A CD 1 ATOM 1955 O OE1 . GLU A 1 304 ? 190.512 94.480 37.943 1.00 32.15 ? 302 GLU A OE1 1 ATOM 1956 O OE2 . GLU A 1 304 ? 189.075 92.808 38.145 1.00 87.48 ? 302 GLU A OE2 1 ATOM 1957 N N . VAL A 1 305 ? 195.324 92.537 38.372 1.00 30.34 ? 303 VAL A N 1 ATOM 1958 C CA . VAL A 1 305 ? 196.597 91.851 38.124 1.00 28.70 ? 303 VAL A CA 1 ATOM 1959 C C . VAL A 1 305 ? 197.713 92.462 39.050 1.00 32.34 ? 303 VAL A C 1 ATOM 1960 O O . VAL A 1 305 ? 198.425 91.727 39.738 1.00 32.32 ? 303 VAL A O 1 ATOM 1961 C CB . VAL A 1 305 ? 196.972 91.894 36.592 1.00 30.14 ? 303 VAL A CB 1 ATOM 1962 C CG1 . VAL A 1 305 ? 198.392 91.416 36.339 1.00 29.30 ? 303 VAL A CG1 1 ATOM 1963 C CG2 . VAL A 1 305 ? 196.008 91.076 35.764 1.00 29.44 ? 303 VAL A CG2 1 ATOM 1964 N N . VAL A 1 306 ? 197.801 93.801 39.077 1.00 28.59 ? 304 VAL A N 1 ATOM 1965 C CA . VAL A 1 306 ? 198.830 94.615 39.749 1.00 28.80 ? 304 VAL A CA 1 ATOM 1966 C C . VAL A 1 306 ? 198.585 94.973 41.240 1.00 28.60 ? 304 VAL A C 1 ATOM 1967 O O . VAL A 1 306 ? 199.530 95.320 41.936 1.00 24.14 ? 304 VAL A O 1 ATOM 1968 C CB . VAL A 1 306 ? 199.074 95.899 38.938 1.00 33.84 ? 304 VAL A CB 1 ATOM 1969 C CG1 . VAL A 1 306 ? 199.822 95.593 37.654 1.00 33.53 ? 304 VAL A CG1 1 ATOM 1970 C CG2 . VAL A 1 306 ? 197.758 96.606 38.629 1.00 34.23 ? 304 VAL A CG2 1 ATOM 1971 N N . ALA A 1 307 ? 197.337 94.898 41.698 1.00 27.07 ? 305 ALA A N 1 ATOM 1972 C CA . ALA A 1 307 ? 196.913 95.223 43.055 1.00 27.02 ? 305 ALA A CA 1 ATOM 1973 C C . ALA A 1 307 ? 197.675 94.373 43.997 1.00 32.67 ? 305 ALA A C 1 ATOM 1974 O O . ALA A 1 307 ? 197.671 93.132 43.836 1.00 31.81 ? 305 ALA A O 1 ATOM 1975 C CB . ALA A 1 307 ? 195.428 94.944 43.217 1.00 27.74 ? 305 ALA A CB 1 ATOM 1976 N N . GLY A 1 308 ? 198.336 95.046 44.956 1.00 28.58 ? 306 GLY A N 1 ATOM 1977 C CA . GLY A 1 308 ? 199.152 94.394 45.973 1.00 27.80 ? 306 GLY A CA 1 ATOM 1978 C C . GLY A 1 308 ? 200.587 94.140 45.554 1.00 34.29 ? 306 GLY A C 1 ATOM 1979 O O . GLY A 1 308 ? 201.400 93.698 46.367 1.00 35.46 ? 306 GLY A O 1 ATOM 1980 N N . SER A 1 309 ? 200.921 94.423 44.289 1.00 31.89 ? 307 SER A N 1 ATOM 1981 C CA . SER A 1 309 ? 202.231 94.135 43.702 1.00 30.83 ? 307 SER A CA 1 ATOM 1982 C C . SER A 1 309 ? 202.702 95.255 42.832 1.00 34.25 ? 307 SER A C 1 ATOM 1983 O O . SER A 1 309 ? 203.538 95.040 41.959 1.00 34.34 ? 307 SER A O 1 ATOM 1984 C CB . SER A 1 309 ? 202.160 92.844 42.891 1.00 31.93 ? 307 SER A CB 1 ATOM 1985 O OG . SER A 1 309 ? 201.891 91.767 43.772 1.00 42.79 ? 307 SER A OG 1 ATOM 1986 N N . GLU A 1 310 ? 202.217 96.467 43.103 1.00 30.79 ? 308 GLU A N 1 ATOM 1987 C CA . GLU A 1 310 ? 202.533 97.682 42.343 1.00 30.58 ? 308 GLU A CA 1 ATOM 1988 C C . GLU A 1 310 ? 204.037 97.895 42.124 1.00 35.01 ? 308 GLU A C 1 ATOM 1989 O O . GLU A 1 310 ? 204.446 98.177 40.994 1.00 33.20 ? 308 GLU A O 1 ATOM 1990 C CB . GLU A 1 310 ? 201.885 98.905 42.997 1.00 31.67 ? 308 GLU A CB 1 ATOM 1991 C CG . GLU A 1 310 ? 200.360 98.905 43.030 1.00 37.20 ? 308 GLU A CG 1 ATOM 1992 C CD . GLU A 1 310 ? 199.640 98.129 44.119 1.00 57.11 ? 308 GLU A CD 1 ATOM 1993 O OE1 . GLU A 1 310 ? 200.299 97.397 44.896 1.00 56.71 ? 308 GLU A OE1 1 ATOM 1994 O OE2 . GLU A 1 310 ? 198.394 98.243 44.176 1.00 48.14 ? 308 GLU A OE2 1 ATOM 1995 N N . GLY A 1 311 ? 204.833 97.673 43.181 1.00 33.06 ? 309 GLY A N 1 ATOM 1996 C CA . GLY A 1 311 ? 206.286 97.817 43.147 1.00 33.38 ? 309 GLY A CA 1 ATOM 1997 C C . GLY A 1 311 ? 206.935 96.920 42.118 1.00 38.66 ? 309 GLY A C 1 ATOM 1998 O O . GLY A 1 311 ? 207.681 97.402 41.265 1.00 39.28 ? 309 GLY A O 1 ATOM 1999 N N . ALA A 1 312 ? 206.596 95.613 42.157 1.00 34.83 ? 310 ALA A N 1 ATOM 2000 C CA . ALA A 1 312 ? 207.084 94.590 41.217 1.00 34.53 ? 310 ALA A CA 1 ATOM 2001 C C . ALA A 1 312 ? 206.661 94.874 39.763 1.00 37.95 ? 310 ALA A C 1 ATOM 2002 O O . ALA A 1 312 ? 207.437 94.641 38.833 1.00 37.77 ? 310 ALA A O 1 ATOM 2003 C CB . ALA A 1 312 ? 206.568 93.215 41.639 1.00 35.14 ? 310 ALA A CB 1 ATOM 2004 N N . ALA A 1 313 ? 205.420 95.353 39.587 1.00 33.07 ? 311 ALA A N 1 ATOM 2005 C CA . ALA A 1 313 ? 204.788 95.632 38.308 1.00 32.40 ? 311 ALA A CA 1 ATOM 2006 C C . ALA A 1 313 ? 205.238 96.937 37.674 1.00 37.60 ? 311 ALA A C 1 ATOM 2007 O O . ALA A 1 313 ? 205.134 97.068 36.462 1.00 37.07 ? 311 ALA A O 1 ATOM 2008 C CB . ALA A 1 313 ? 203.271 95.628 38.480 1.00 32.64 ? 311 ALA A CB 1 ATOM 2009 N N . GLU A 1 314 ? 205.661 97.920 38.490 1.00 35.50 ? 312 GLU A N 1 ATOM 2010 C CA . GLU A 1 314 ? 206.088 99.257 38.055 1.00 35.94 ? 312 GLU A CA 1 ATOM 2011 C C . GLU A 1 314 ? 207.082 99.186 36.885 1.00 38.11 ? 312 GLU A C 1 ATOM 2012 O O . GLU A 1 314 ? 208.113 98.509 36.987 1.00 39.57 ? 312 GLU A O 1 ATOM 2013 C CB . GLU A 1 314 ? 206.707 100.040 39.237 1.00 37.46 ? 312 GLU A CB 1 ATOM 2014 C CG . GLU A 1 314 ? 206.732 101.544 39.041 1.00 50.54 ? 312 GLU A CG 1 ATOM 2015 C CD . GLU A 1 314 ? 207.581 102.308 40.039 1.00 76.14 ? 312 GLU A CD 1 ATOM 2016 O OE1 . GLU A 1 314 ? 207.312 102.203 41.258 1.00 80.74 ? 312 GLU A OE1 1 ATOM 2017 O OE2 . GLU A 1 314 ? 208.508 103.027 39.601 1.00 68.87 ? 312 GLU A OE2 1 ATOM 2018 N N . GLY A 1 315 ? 206.743 99.858 35.798 1.00 30.80 ? 313 GLY A N 1 ATOM 2019 C CA . GLY A 1 315 ? 207.564 99.890 34.603 1.00 30.69 ? 313 GLY A CA 1 ATOM 2020 C C . GLY A 1 315 ? 207.143 98.914 33.522 1.00 35.91 ? 313 GLY A C 1 ATOM 2021 O O . GLY A 1 315 ? 207.796 98.834 32.479 1.00 36.97 ? 313 GLY A O 1 ATOM 2022 N N . ALA A 1 316 ? 206.055 98.177 33.746 1.00 31.40 ? 314 ALA A N 1 ATOM 2023 C CA . ALA A 1 316 ? 205.586 97.200 32.778 1.00 31.40 ? 314 ALA A CA 1 ATOM 2024 C C . ALA A 1 316 ? 204.986 97.857 31.573 1.00 36.03 ? 314 ALA A C 1 ATOM 2025 O O . ALA A 1 316 ? 204.414 98.938 31.674 1.00 36.29 ? 314 ALA A O 1 ATOM 2026 C CB . ALA A 1 316 ? 204.566 96.270 33.402 1.00 32.05 ? 314 ALA A CB 1 ATOM 2027 N N . ILE A 1 317 ? 205.163 97.213 30.424 1.00 32.12 ? 315 ILE A N 1 ATOM 2028 C CA . ILE A 1 317 ? 204.573 97.588 29.151 1.00 32.14 ? 315 ILE A CA 1 ATOM 2029 C C . ILE A 1 317 ? 203.552 96.483 28.881 1.00 35.97 ? 315 ILE A C 1 ATOM 2030 O O . ILE A 1 317 ? 203.880 95.269 28.925 1.00 34.43 ? 315 ILE A O 1 ATOM 2031 C CB . ILE A 1 317 ? 205.603 97.702 28.011 1.00 35.69 ? 315 ILE A CB 1 ATOM 2032 C CG1 . ILE A 1 317 ? 206.507 98.899 28.205 1.00 36.30 ? 315 ILE A CG1 1 ATOM 2033 C CG2 . ILE A 1 317 ? 204.920 97.754 26.652 1.00 36.95 ? 315 ILE A CG2 1 ATOM 2034 C CD1 . ILE A 1 317 ? 207.825 98.636 27.635 1.00 48.44 ? 315 ILE A CD1 1 ATOM 2035 N N . THR A 1 318 ? 202.292 96.904 28.718 1.00 31.60 ? 316 THR A N 1 ATOM 2036 C CA . THR A 1 318 ? 201.228 95.950 28.451 1.00 31.30 ? 316 THR A CA 1 ATOM 2037 C C . THR A 1 318 ? 200.474 96.366 27.206 1.00 35.95 ? 316 THR A C 1 ATOM 2038 O O . THR A 1 318 ? 200.543 97.514 26.765 1.00 35.36 ? 316 THR A O 1 ATOM 2039 C CB . THR A 1 318 ? 200.309 95.673 29.652 1.00 32.08 ? 316 THR A CB 1 ATOM 2040 O OG1 . THR A 1 318 ? 199.504 96.823 29.881 1.00 41.08 ? 316 THR A OG1 1 ATOM 2041 C CG2 . THR A 1 318 ? 201.044 95.282 30.897 1.00 24.13 ? 316 THR A CG2 1 ATOM 2042 N N . ILE A 1 319 ? 199.795 95.393 26.619 1.00 33.11 ? 317 ILE A N 1 ATOM 2043 C CA . ILE A 1 319 ? 199.009 95.552 25.418 1.00 32.55 ? 317 ILE A CA 1 ATOM 2044 C C . ILE A 1 319 ? 197.572 95.193 25.724 1.00 35.53 ? 317 ILE A C 1 ATOM 2045 O O . ILE A 1 319 ? 197.293 94.176 26.356 1.00 34.80 ? 317 ILE A O 1 ATOM 2046 C CB . ILE A 1 319 ? 199.543 94.591 24.330 1.00 35.51 ? 317 ILE A CB 1 ATOM 2047 C CG1 . ILE A 1 319 ? 201.106 94.528 24.295 1.00 36.54 ? 317 ILE A CG1 1 ATOM 2048 C CG2 . ILE A 1 319 ? 198.937 94.890 22.971 1.00 34.92 ? 317 ILE A CG2 1 ATOM 2049 C CD1 . ILE A 1 319 ? 201.832 95.777 23.906 1.00 49.83 ? 317 ILE A CD1 1 ATOM 2050 N N . GLU A 1 320 ? 196.665 96.021 25.249 1.00 30.44 ? 318 GLU A N 1 ATOM 2051 C CA . GLU A 1 320 ? 195.258 95.737 25.241 1.00 28.63 ? 318 GLU A CA 1 ATOM 2052 C C . GLU A 1 320 ? 194.830 96.103 23.862 1.00 32.98 ? 318 GLU A C 1 ATOM 2053 O O . GLU A 1 320 ? 195.444 96.975 23.227 1.00 31.11 ? 318 GLU A O 1 ATOM 2054 C CB . GLU A 1 320 ? 194.449 96.518 26.279 1.00 29.45 ? 318 GLU A CB 1 ATOM 2055 C CG . GLU A 1 320 ? 193.641 95.621 27.215 1.00 45.10 ? 318 GLU A CG 1 ATOM 2056 C CD . GLU A 1 320 ? 192.753 94.448 26.767 1.00 58.51 ? 318 GLU A CD 1 ATOM 2057 O OE1 . GLU A 1 320 ? 192.215 93.765 27.669 1.00 44.89 ? 318 GLU A OE1 1 ATOM 2058 O OE2 . GLU A 1 320 ? 192.570 94.212 25.550 1.00 32.93 ? 318 GLU A OE2 1 ATOM 2059 N N . LEU A 1 321 ? 193.781 95.415 23.402 1.00 30.96 ? 319 LEU A N 1 ATOM 2060 C CA . LEU A 1 321 ? 193.135 95.658 22.128 1.00 30.80 ? 319 LEU A CA 1 ATOM 2061 C C . LEU A 1 321 ? 192.536 97.065 22.224 1.00 34.69 ? 319 LEU A C 1 ATOM 2062 O O . LEU A 1 321 ? 192.019 97.445 23.285 1.00 33.97 ? 319 LEU A O 1 ATOM 2063 C CB . LEU A 1 321 ? 192.022 94.637 21.968 1.00 31.08 ? 319 LEU A CB 1 ATOM 2064 C CG . LEU A 1 321 ? 192.395 93.164 21.856 1.00 36.90 ? 319 LEU A CG 1 ATOM 2065 C CD1 . LEU A 1 321 ? 192.818 92.752 20.434 1.00 37.38 ? 319 LEU A CD1 1 ATOM 2066 C CD2 . LEU A 1 321 ? 193.546 92.899 22.744 1.00 38.87 ? 319 LEU A CD2 1 ATOM 2067 N N . ALA A 1 322 ? 192.687 97.842 21.129 1.00 32.65 ? 320 ALA A N 1 ATOM 2068 C CA . ALA A 1 322 ? 192.189 99.221 21.097 1.00 33.68 ? 320 ALA A CA 1 ATOM 2069 C C . ALA A 1 322 ? 190.668 99.279 21.143 1.00 38.38 ? 320 ALA A C 1 ATOM 2070 O O . ALA A 1 322 ? 189.996 98.553 20.409 1.00 37.85 ? 320 ALA A O 1 ATOM 2071 C CB . ALA A 1 322 ? 192.716 99.952 19.869 1.00 34.44 ? 320 ALA A CB 1 ATOM 2072 N N . SER A 1 323 ? 190.139 100.098 22.046 1.00 36.48 ? 321 SER A N 1 ATOM 2073 C CA . SER A 1 323 ? 188.700 100.274 22.218 1.00 38.10 ? 321 SER A CA 1 ATOM 2074 C C . SER A 1 323 ? 188.390 101.695 22.697 1.00 42.61 ? 321 SER A C 1 ATOM 2075 O O . SER A 1 323 ? 189.299 102.495 22.923 1.00 38.96 ? 321 SER A O 1 ATOM 2076 C CB . SER A 1 323 ? 188.123 99.239 23.190 1.00 43.92 ? 321 SER A CB 1 ATOM 2077 O OG . SER A 1 323 ? 188.585 99.461 24.516 1.00 56.18 ? 321 SER A OG 1 ATOM 2078 N N . TYR A 1 324 ? 187.092 101.982 22.830 1.00 43.91 ? 322 TYR A N 1 ATOM 2079 C CA . TYR A 1 324 ? 186.528 103.240 23.268 1.00 46.35 ? 322 TYR A CA 1 ATOM 2080 C C . TYR A 1 324 ? 185.471 103.015 24.347 1.00 51.15 ? 322 TYR A C 1 ATOM 2081 O O . TYR A 1 324 ? 184.865 101.941 24.400 1.00 48.65 ? 322 TYR A O 1 ATOM 2082 C CB . TYR A 1 324 ? 185.925 103.984 22.056 1.00 50.39 ? 322 TYR A CB 1 ATOM 2083 C CG . TYR A 1 324 ? 187.001 104.453 21.101 1.00 56.65 ? 322 TYR A CG 1 ATOM 2084 C CD1 . TYR A 1 324 ? 187.891 105.464 21.465 1.00 59.10 ? 322 TYR A CD1 1 ATOM 2085 C CD2 . TYR A 1 324 ? 187.183 103.835 19.865 1.00 58.52 ? 322 TYR A CD2 1 ATOM 2086 C CE1 . TYR A 1 324 ? 188.934 105.847 20.626 1.00 60.27 ? 322 TYR A CE1 1 ATOM 2087 C CE2 . TYR A 1 324 ? 188.207 104.233 19.003 1.00 60.26 ? 322 TYR A CE2 1 ATOM 2088 C CZ . TYR A 1 324 ? 189.081 105.241 19.390 1.00 69.97 ? 322 TYR A CZ 1 ATOM 2089 O OH . TYR A 1 324 ? 190.107 105.640 18.564 1.00 74.16 ? 322 TYR A OH 1 ATOM 2090 N N . PRO A 1 325 ? 185.215 104.006 25.227 1.00 51.83 ? 323 PRO A N 1 ATOM 2091 C CA . PRO A 1 325 ? 184.147 103.819 26.207 1.00 51.90 ? 323 PRO A CA 1 ATOM 2092 C C . PRO A 1 325 ? 182.799 104.077 25.524 1.00 55.29 ? 323 PRO A C 1 ATOM 2093 O O . PRO A 1 325 ? 182.714 104.851 24.557 1.00 53.89 ? 323 PRO A O 1 ATOM 2094 C CB . PRO A 1 325 ? 184.483 104.843 27.282 1.00 53.70 ? 323 PRO A CB 1 ATOM 2095 C CG . PRO A 1 325 ? 185.098 105.964 26.533 1.00 58.65 ? 323 PRO A CG 1 ATOM 2096 C CD . PRO A 1 325 ? 185.796 105.366 25.331 1.00 54.36 ? 323 PRO A CD 1 ATOM 2097 N N . ILE A 1 326 ? 181.768 103.346 25.967 1.00 51.98 ? 324 ILE A N 1 ATOM 2098 C CA . ILE A 1 326 ? 180.424 103.479 25.420 1.00 51.33 ? 324 ILE A CA 1 ATOM 2099 C C . ILE A 1 326 ? 179.548 104.034 26.546 1.00 54.59 ? 324 ILE A C 1 ATOM 2100 O O . ILE A 1 326 ? 179.330 103.381 27.567 1.00 53.36 ? 324 ILE A O 1 ATOM 2101 C CB . ILE A 1 326 ? 179.933 102.199 24.671 1.00 54.07 ? 324 ILE A CB 1 ATOM 2102 C CG1 . ILE A 1 326 ? 179.955 100.951 25.532 1.00 54.13 ? 324 ILE A CG1 1 ATOM 2103 C CG2 . ILE A 1 326 ? 180.841 101.947 23.458 1.00 55.40 ? 324 ILE A CG2 1 ATOM 2104 C CD1 . ILE A 1 326 ? 179.392 99.743 24.873 1.00 52.49 ? 324 ILE A CD1 1 ATOM 2105 N N . SER A 1 327 ? 179.230 105.340 26.414 1.00 52.28 ? 325 SER A N 1 ATOM 2106 C CA . SER A 1 327 ? 178.499 106.193 27.379 1.00 51.92 ? 325 SER A CA 1 ATOM 2107 C C . SER A 1 327 ? 177.213 105.549 27.917 1.00 52.55 ? 325 SER A C 1 ATOM 2108 O O . SER A 1 327 ? 177.037 105.451 29.144 1.00 51.48 ? 325 SER A O 1 ATOM 2109 C CB . SER A 1 327 ? 178.219 107.580 26.777 1.00 54.80 ? 325 SER A CB 1 ATOM 2110 O OG . SER A 1 327 ? 177.311 108.362 27.543 1.00 60.50 ? 325 SER A OG 1 ATOM 2111 N N . ASP A 1 328 ? 176.334 105.107 26.986 1.00 45.27 ? 326 ASP A N 1 ATOM 2112 C CA . ASP A 1 328 ? 175.082 104.443 27.295 1.00 44.39 ? 326 ASP A CA 1 ATOM 2113 C C . ASP A 1 328 ? 175.271 103.206 28.188 1.00 45.35 ? 326 ASP A C 1 ATOM 2114 O O . ASP A 1 328 ? 174.383 102.914 29.008 1.00 46.46 ? 326 ASP A O 1 ATOM 2115 C CB . ASP A 1 328 ? 174.318 104.133 26.008 1.00 47.24 ? 326 ASP A CB 1 ATOM 2116 C CG . ASP A 1 328 ? 173.750 105.373 25.315 1.00 63.57 ? 326 ASP A CG 1 ATOM 2117 O OD1 . ASP A 1 328 ? 173.866 106.488 25.888 1.00 66.29 ? 326 ASP A OD1 1 ATOM 2118 O OD2 . ASP A 1 328 ? 173.145 105.223 24.225 1.00 66.22 ? 326 ASP A OD2 1 ATOM 2119 N N . PHE A 1 329 ? 176.463 102.545 28.102 1.00 36.70 ? 327 PHE A N 1 ATOM 2120 C CA . PHE A 1 329 ? 176.774 101.407 28.956 1.00 34.48 ? 327 PHE A CA 1 ATOM 2121 C C . PHE A 1 329 ? 177.039 101.819 30.392 1.00 39.76 ? 327 PHE A C 1 ATOM 2122 O O . PHE A 1 329 ? 176.445 101.233 31.299 1.00 38.57 ? 327 PHE A O 1 ATOM 2123 C CB . PHE A 1 329 ? 177.910 100.509 28.420 1.00 33.91 ? 327 PHE A CB 1 ATOM 2124 C CG . PHE A 1 329 ? 178.141 99.297 29.301 1.00 32.04 ? 327 PHE A CG 1 ATOM 2125 C CD1 . PHE A 1 329 ? 177.132 98.361 29.506 1.00 31.11 ? 327 PHE A CD1 1 ATOM 2126 C CD2 . PHE A 1 329 ? 179.353 99.117 29.960 1.00 31.96 ? 327 PHE A CD2 1 ATOM 2127 C CE1 . PHE A 1 329 ? 177.342 97.259 30.338 1.00 31.35 ? 327 PHE A CE1 1 ATOM 2128 C CE2 . PHE A 1 329 ? 179.567 97.999 30.775 1.00 33.00 ? 327 PHE A CE2 1 ATOM 2129 C CZ . PHE A 1 329 ? 178.559 97.086 30.967 1.00 30.29 ? 327 PHE A CZ 1 ATOM 2130 N N . ALA A 1 330 ? 177.947 102.804 30.599 1.00 37.36 ? 328 ALA A N 1 ATOM 2131 C CA . ALA A 1 330 ? 178.278 103.318 31.930 1.00 36.79 ? 328 ALA A CA 1 ATOM 2132 C C . ALA A 1 330 ? 177.013 103.764 32.662 1.00 41.21 ? 328 ALA A C 1 ATOM 2133 O O . ALA A 1 330 ? 176.884 103.465 33.846 1.00 41.03 ? 328 ALA A O 1 ATOM 2134 C CB . ALA A 1 330 ? 179.279 104.457 31.829 1.00 37.35 ? 328 ALA A CB 1 ATOM 2135 N N . SER A 1 331 ? 176.045 104.391 31.939 1.00 38.80 ? 329 SER A N 1 ATOM 2136 C CA . SER A 1 331 ? 174.755 104.828 32.483 1.00 39.59 ? 329 SER A CA 1 ATOM 2137 C C . SER A 1 331 ? 173.968 103.602 32.932 1.00 45.08 ? 329 SER A C 1 ATOM 2138 O O . SER A 1 331 ? 173.569 103.538 34.094 1.00 45.62 ? 329 SER A O 1 ATOM 2139 C CB . SER A 1 331 ? 173.959 105.598 31.434 1.00 45.44 ? 329 SER A CB 1 ATOM 2140 O OG . SER A 1 331 ? 174.291 106.977 31.397 1.00 58.46 ? 329 SER A OG 1 ATOM 2141 N N . TYR A 1 332 ? 173.808 102.604 32.024 1.00 40.60 ? 330 TYR A N 1 ATOM 2142 C CA . TYR A 1 332 ? 173.116 101.334 32.265 1.00 38.88 ? 330 TYR A CA 1 ATOM 2143 C C . TYR A 1 332 ? 173.700 100.593 33.471 1.00 40.29 ? 330 TYR A C 1 ATOM 2144 O O . TYR A 1 332 ? 172.957 100.184 34.363 1.00 38.65 ? 330 TYR A O 1 ATOM 2145 C CB . TYR A 1 332 ? 173.171 100.453 30.990 1.00 39.59 ? 330 TYR A CB 1 ATOM 2146 C CG . TYR A 1 332 ? 172.737 99.021 31.210 1.00 40.82 ? 330 TYR A CG 1 ATOM 2147 C CD1 . TYR A 1 332 ? 171.398 98.652 31.108 1.00 42.58 ? 330 TYR A CD1 1 ATOM 2148 C CD2 . TYR A 1 332 ? 173.667 98.027 31.517 1.00 41.14 ? 330 TYR A CD2 1 ATOM 2149 C CE1 . TYR A 1 332 ? 170.997 97.328 31.301 1.00 42.87 ? 330 TYR A CE1 1 ATOM 2150 C CE2 . TYR A 1 332 ? 173.274 96.706 31.728 1.00 41.46 ? 330 TYR A CE2 1 ATOM 2151 C CZ . TYR A 1 332 ? 171.936 96.365 31.632 1.00 46.83 ? 330 TYR A CZ 1 ATOM 2152 O OH . TYR A 1 332 ? 171.542 95.072 31.864 1.00 45.88 ? 330 TYR A OH 1 ATOM 2153 N N . PHE A 1 333 ? 175.027 100.420 33.489 1.00 37.17 ? 331 PHE A N 1 ATOM 2154 C CA . PHE A 1 333 ? 175.725 99.693 34.543 1.00 37.00 ? 331 PHE A CA 1 ATOM 2155 C C . PHE A 1 333 ? 175.617 100.349 35.929 1.00 42.82 ? 331 PHE A C 1 ATOM 2156 O O . PHE A 1 333 ? 175.158 99.707 36.882 1.00 41.00 ? 331 PHE A O 1 ATOM 2157 C CB . PHE A 1 333 ? 177.197 99.427 34.171 1.00 37.80 ? 331 PHE A CB 1 ATOM 2158 C CG . PHE A 1 333 ? 177.793 98.317 35.010 1.00 38.37 ? 331 PHE A CG 1 ATOM 2159 C CD1 . PHE A 1 333 ? 177.610 96.979 34.656 1.00 39.37 ? 331 PHE A CD1 1 ATOM 2160 C CD2 . PHE A 1 333 ? 178.462 98.602 36.205 1.00 38.65 ? 331 PHE A CD2 1 ATOM 2161 C CE1 . PHE A 1 333 ? 178.115 95.952 35.461 1.00 39.57 ? 331 PHE A CE1 1 ATOM 2162 C CE2 . PHE A 1 333 ? 178.987 97.575 36.991 1.00 40.49 ? 331 PHE A CE2 1 ATOM 2163 C CZ . PHE A 1 333 ? 178.807 96.256 36.614 1.00 38.48 ? 331 PHE A CZ 1 ATOM 2164 N N . GLN A 1 334 ? 176.046 101.621 36.039 1.00 41.22 ? 332 GLN A N 1 ATOM 2165 C CA . GLN A 1 334 ? 176.036 102.367 37.302 1.00 40.72 ? 332 GLN A CA 1 ATOM 2166 C C . GLN A 1 334 ? 174.638 102.526 37.911 1.00 43.49 ? 332 GLN A C 1 ATOM 2167 O O . GLN A 1 334 ? 174.512 102.777 39.115 1.00 42.08 ? 332 GLN A O 1 ATOM 2168 C CB . GLN A 1 334 ? 176.723 103.721 37.139 1.00 41.79 ? 332 GLN A CB 1 ATOM 2169 C CG . GLN A 1 334 ? 178.203 103.629 36.824 1.00 40.91 ? 332 GLN A CG 1 ATOM 2170 C CD . GLN A 1 334 ? 178.782 105.011 36.713 1.00 57.06 ? 332 GLN A CD 1 ATOM 2171 O OE1 . GLN A 1 334 ? 178.628 105.707 35.694 1.00 47.13 ? 332 GLN A OE1 1 ATOM 2172 N NE2 . GLN A 1 334 ? 179.402 105.461 37.795 1.00 53.81 ? 332 GLN A NE2 1 ATOM 2173 N N . SER A 1 335 ? 173.600 102.361 37.074 1.00 41.17 ? 333 SER A N 1 ATOM 2174 C CA . SER A 1 335 ? 172.195 102.426 37.461 1.00 41.64 ? 333 SER A CA 1 ATOM 2175 C C . SER A 1 335 ? 171.645 101.036 37.864 1.00 46.32 ? 333 SER A C 1 ATOM 2176 O O . SER A 1 335 ? 170.457 100.913 38.169 1.00 46.63 ? 333 SER A O 1 ATOM 2177 C CB . SER A 1 335 ? 171.360 103.051 36.348 1.00 45.24 ? 333 SER A CB 1 ATOM 2178 O OG . SER A 1 335 ? 171.214 102.142 35.269 1.00 59.92 ? 333 SER A OG 1 ATOM 2179 N N . LEU A 1 336 ? 172.478 100.026 37.903 1.00 43.29 ? 334 LEU A N 1 ATOM 2180 C CA . LEU A 1 336 ? 171.956 98.753 38.273 1.00 44.02 ? 334 LEU A CA 1 ATOM 2181 C C . LEU A 1 336 ? 171.875 98.682 39.754 1.00 53.42 ? 334 LEU A C 1 ATOM 2182 O O . LEU A 1 336 ? 172.666 99.247 40.454 1.00 52.95 ? 334 LEU A O 1 ATOM 2183 C CB . LEU A 1 336 ? 172.769 97.607 37.712 1.00 43.17 ? 334 LEU A CB 1 ATOM 2184 C CG . LEU A 1 336 ? 172.810 97.410 36.207 1.00 45.90 ? 334 LEU A CG 1 ATOM 2185 C CD1 . LEU A 1 336 ? 174.017 96.603 35.851 1.00 45.73 ? 334 LEU A CD1 1 ATOM 2186 C CD2 . LEU A 1 336 ? 171.588 96.752 35.642 1.00 44.87 ? 334 LEU A CD2 1 ATOM 2187 N N . ASP A 1 337 ? 170.882 97.971 40.226 1.00 54.17 ? 335 ASP A N 1 ATOM 2188 C CA . ASP A 1 337 ? 170.528 98.004 41.600 1.00 55.78 ? 335 ASP A CA 1 ATOM 2189 C C . ASP A 1 337 ? 170.168 96.582 41.901 1.00 60.45 ? 335 ASP A C 1 ATOM 2190 O O . ASP A 1 337 ? 169.734 95.868 41.032 1.00 59.89 ? 335 ASP A O 1 ATOM 2191 C CB . ASP A 1 337 ? 169.381 99.023 41.748 1.00 58.71 ? 335 ASP A CB 1 ATOM 2192 C CG . ASP A 1 337 ? 168.898 99.202 43.147 1.00 80.52 ? 335 ASP A CG 1 ATOM 2193 O OD1 . ASP A 1 337 ? 169.645 99.682 44.009 1.00 84.22 ? 335 ASP A OD1 1 ATOM 2194 O OD2 . ASP A 1 337 ? 167.751 98.854 43.384 1.00 86.27 ? 335 ASP A OD2 1 ATOM 2195 N N . PRO A 1 338 ? 170.395 96.187 43.222 1.00 58.85 ? 336 PRO A N 1 ATOM 2196 C CA . PRO A 1 338 ? 170.143 94.766 43.453 1.00 60.00 ? 336 PRO A CA 1 ATOM 2197 C C . PRO A 1 338 ? 168.678 94.375 43.519 1.00 67.33 ? 336 PRO A C 1 ATOM 2198 O O . PRO A 1 338 ? 168.329 93.215 43.566 1.00 65.36 ? 336 PRO A O 1 ATOM 2199 C CB . PRO A 1 338 ? 170.833 94.510 44.766 1.00 61.45 ? 336 PRO A CB 1 ATOM 2200 C CG . PRO A 1 338 ? 170.598 95.716 45.518 1.00 65.15 ? 336 PRO A CG 1 ATOM 2201 C CD . PRO A 1 338 ? 170.894 96.770 44.562 1.00 60.37 ? 336 PRO A CD 1 ATOM 2202 N N . TRP A 1 339 ? 167.816 95.363 43.509 1.00 68.39 ? 337 TRP A N 1 ATOM 2203 C CA . TRP A 1 339 ? 166.406 95.114 43.606 1.00 70.17 ? 337 TRP A CA 1 ATOM 2204 C C . TRP A 1 339 ? 165.833 95.192 42.244 1.00 72.22 ? 337 TRP A C 1 ATOM 2205 O O . TRP A 1 339 ? 164.908 94.497 41.944 1.00 72.83 ? 337 TRP A O 1 ATOM 2206 C CB . TRP A 1 339 ? 165.783 96.106 44.579 1.00 70.77 ? 337 TRP A CB 1 ATOM 2207 C CG . TRP A 1 339 ? 166.435 95.918 45.887 1.00 72.97 ? 337 TRP A CG 1 ATOM 2208 C CD1 . TRP A 1 339 ? 167.365 96.713 46.461 1.00 76.05 ? 337 TRP A CD1 1 ATOM 2209 C CD2 . TRP A 1 339 ? 166.287 94.792 46.747 1.00 73.21 ? 337 TRP A CD2 1 ATOM 2210 N NE1 . TRP A 1 339 ? 167.786 96.169 47.642 1.00 75.66 ? 337 TRP A NE1 1 ATOM 2211 C CE2 . TRP A 1 339 ? 167.131 94.989 47.839 1.00 77.27 ? 337 TRP A CE2 1 ATOM 2212 C CE3 . TRP A 1 339 ? 165.505 93.642 46.703 1.00 74.81 ? 337 TRP A CE3 1 ATOM 2213 C CZ2 . TRP A 1 339 ? 167.213 94.090 48.879 1.00 76.79 ? 337 TRP A CZ2 1 ATOM 2214 C CZ3 . TRP A 1 339 ? 165.589 92.749 47.733 1.00 76.52 ? 337 TRP A CZ3 1 ATOM 2215 C CH2 . TRP A 1 339 ? 166.435 92.975 48.809 1.00 77.16 ? 337 TRP A CH2 1 ATOM 2216 N N . ASN A 1 340 ? 166.446 96.000 41.399 1.00 66.83 ? 338 ASN A N 1 ATOM 2217 C CA . ASN A 1 340 ? 166.020 96.105 40.021 1.00 65.88 ? 338 ASN A CA 1 ATOM 2218 C C . ASN A 1 340 ? 166.661 95.136 39.027 1.00 66.84 ? 338 ASN A C 1 ATOM 2219 O O . ASN A 1 340 ? 166.133 94.908 37.971 1.00 67.36 ? 338 ASN A O 1 ATOM 2220 C CB . ASN A 1 340 ? 165.977 97.582 39.540 1.00 67.95 ? 338 ASN A CB 1 ATOM 2221 C CG . ASN A 1 340 ? 167.304 98.121 39.002 1.00 88.46 ? 338 ASN A CG 1 ATOM 2222 O OD1 . ASN A 1 340 ? 168.132 97.404 38.471 1.00 84.24 ? 338 ASN A OD1 1 ATOM 2223 N ND2 . ASN A 1 340 ? 167.469 99.422 39.100 1.00 74.16 ? 338 ASN A ND2 1 ATOM 2224 N N . ASN A 1 341 ? 167.774 94.533 39.385 1.00 59.44 ? 339 ASN A N 1 ATOM 2225 C CA . ASN A 1 341 ? 168.458 93.606 38.507 1.00 56.98 ? 339 ASN A CA 1 ATOM 2226 C C . ASN A 1 341 ? 168.351 92.216 39.062 1.00 58.89 ? 339 ASN A C 1 ATOM 2227 O O . ASN A 1 341 ? 169.203 91.772 39.782 1.00 59.05 ? 339 ASN A O 1 ATOM 2228 C CB . ASN A 1 341 ? 169.917 94.012 38.386 1.00 50.32 ? 339 ASN A CB 1 ATOM 2229 C CG . ASN A 1 341 ? 170.595 93.447 37.182 1.00 57.81 ? 339 ASN A CG 1 ATOM 2230 O OD1 . ASN A 1 341 ? 169.979 93.098 36.204 1.00 52.89 ? 339 ASN A OD1 1 ATOM 2231 N ND2 . ASN A 1 341 ? 171.880 93.388 37.244 1.00 49.34 ? 339 ASN A ND2 1 ATOM 2232 N N . SER A 1 342 ? 167.272 91.537 38.745 1.00 53.07 ? 340 SER A N 1 ATOM 2233 C CA . SER A 1 342 ? 167.067 90.206 39.257 1.00 51.19 ? 340 SER A CA 1 ATOM 2234 C C . SER A 1 342 ? 167.253 89.188 38.173 1.00 50.30 ? 340 SER A C 1 ATOM 2235 O O . SER A 1 342 ? 167.273 88.008 38.426 1.00 48.97 ? 340 SER A O 1 ATOM 2236 C CB . SER A 1 342 ? 165.683 90.085 39.879 1.00 54.23 ? 340 SER A CB 1 ATOM 2237 O OG . SER A 1 342 ? 164.692 90.262 38.908 1.00 65.71 ? 340 SER A OG 1 ATOM 2238 N N . ARG A 1 343 ? 167.391 89.656 36.954 1.00 43.41 ? 341 ARG A N 1 ATOM 2239 C CA . ARG A 1 343 ? 167.541 88.766 35.844 1.00 41.91 ? 341 ARG A CA 1 ATOM 2240 C C . ARG A 1 343 ? 168.931 88.180 35.830 1.00 44.37 ? 341 ARG A C 1 ATOM 2241 O O . ARG A 1 343 ? 169.138 87.089 35.389 1.00 44.57 ? 341 ARG A O 1 ATOM 2242 C CB . ARG A 1 343 ? 167.211 89.486 34.563 1.00 38.24 ? 341 ARG A CB 1 ATOM 2243 C CG . ARG A 1 343 ? 168.162 90.572 34.180 1.00 33.41 ? 341 ARG A CG 1 ATOM 2244 C CD . ARG A 1 343 ? 167.765 91.059 32.838 1.00 29.75 ? 341 ARG A CD 1 ATOM 2245 N NE . ARG A 1 343 ? 168.533 92.183 32.421 1.00 20.63 ? 341 ARG A NE 1 ATOM 2246 C CZ . ARG A 1 343 ? 168.291 92.843 31.327 1.00 31.62 ? 341 ARG A CZ 1 ATOM 2247 N NH1 . ARG A 1 343 ? 167.293 92.518 30.569 1.00 22.28 ? 341 ARG A NH1 1 ATOM 2248 N NH2 . ARG A 1 343 ? 169.047 93.839 31.019 1.00 27.17 ? 341 ARG A NH2 1 ATOM 2249 N N . ASN A 1 344 ? 169.867 88.897 36.402 1.00 38.15 ? 342 ASN A N 1 ATOM 2250 C CA . ASN A 1 344 ? 171.221 88.433 36.559 1.00 36.94 ? 342 ASN A CA 1 ATOM 2251 C C . ASN A 1 344 ? 171.333 87.680 37.918 1.00 40.44 ? 342 ASN A C 1 ATOM 2252 O O . ASN A 1 344 ? 171.408 88.324 38.981 1.00 39.59 ? 342 ASN A O 1 ATOM 2253 C CB . ASN A 1 344 ? 172.198 89.605 36.479 1.00 33.88 ? 342 ASN A CB 1 ATOM 2254 C CG . ASN A 1 344 ? 173.633 89.164 36.612 1.00 47.29 ? 342 ASN A CG 1 ATOM 2255 O OD1 . ASN A 1 344 ? 173.956 87.954 36.752 1.00 35.16 ? 342 ASN A OD1 1 ATOM 2256 N ND2 . ASN A 1 344 ? 174.530 90.139 36.601 1.00 33.89 ? 342 ASN A ND2 1 ATOM 2257 N N . PRO A 1 345 ? 171.399 86.322 37.880 1.00 36.14 ? 343 PRO A N 1 ATOM 2258 C CA . PRO A 1 345 ? 171.465 85.551 39.134 1.00 35.10 ? 343 PRO A CA 1 ATOM 2259 C C . PRO A 1 345 ? 172.748 85.690 39.937 1.00 40.32 ? 343 PRO A C 1 ATOM 2260 O O . PRO A 1 345 ? 172.755 85.289 41.105 1.00 40.52 ? 343 PRO A O 1 ATOM 2261 C CB . PRO A 1 345 ? 171.240 84.107 38.688 1.00 36.68 ? 343 PRO A CB 1 ATOM 2262 C CG . PRO A 1 345 ? 171.576 84.072 37.262 1.00 41.33 ? 343 PRO A CG 1 ATOM 2263 C CD . PRO A 1 345 ? 171.312 85.428 36.703 1.00 37.46 ? 343 PRO A CD 1 ATOM 2264 N N . TRP A 1 346 ? 173.815 86.271 39.344 1.00 36.91 ? 344 TRP A N 1 ATOM 2265 C CA . TRP A 1 346 ? 175.114 86.452 40.008 1.00 36.44 ? 344 TRP A CA 1 ATOM 2266 C C . TRP A 1 346 ? 175.317 87.890 40.499 1.00 41.20 ? 344 TRP A C 1 ATOM 2267 O O . TRP A 1 346 ? 176.330 88.167 41.135 1.00 40.59 ? 344 TRP A O 1 ATOM 2268 C CB . TRP A 1 346 ? 176.263 86.029 39.069 1.00 35.44 ? 344 TRP A CB 1 ATOM 2269 C CG . TRP A 1 346 ? 176.108 84.654 38.493 1.00 36.79 ? 344 TRP A CG 1 ATOM 2270 C CD1 . TRP A 1 346 ? 176.274 83.467 39.150 1.00 40.05 ? 344 TRP A CD1 1 ATOM 2271 C CD2 . TRP A 1 346 ? 175.647 84.323 37.173 1.00 36.46 ? 344 TRP A CD2 1 ATOM 2272 N NE1 . TRP A 1 346 ? 175.960 82.414 38.314 1.00 39.73 ? 344 TRP A NE1 1 ATOM 2273 C CE2 . TRP A 1 346 ? 175.555 82.912 37.100 1.00 40.62 ? 344 TRP A CE2 1 ATOM 2274 C CE3 . TRP A 1 346 ? 175.301 85.081 36.042 1.00 37.77 ? 344 TRP A CE3 1 ATOM 2275 C CZ2 . TRP A 1 346 ? 175.166 82.245 35.929 1.00 39.67 ? 344 TRP A CZ2 1 ATOM 2276 C CZ3 . TRP A 1 346 ? 174.899 84.420 34.886 1.00 39.08 ? 344 TRP A CZ3 1 ATOM 2277 C CH2 . TRP A 1 346 ? 174.846 83.020 34.832 1.00 39.75 ? 344 TRP A CH2 1 ATOM 2278 N N . PHE A 1 347 ? 174.349 88.802 40.224 1.00 39.82 ? 345 PHE A N 1 ATOM 2279 C CA . PHE A 1 347 ? 174.411 90.213 40.630 1.00 40.31 ? 345 PHE A CA 1 ATOM 2280 C C . PHE A 1 347 ? 174.427 90.439 42.148 1.00 46.62 ? 345 PHE A C 1 ATOM 2281 O O . PHE A 1 347 ? 175.141 91.328 42.624 1.00 45.88 ? 345 PHE A O 1 ATOM 2282 C CB . PHE A 1 347 ? 173.288 91.034 39.982 1.00 42.04 ? 345 PHE A CB 1 ATOM 2283 C CG . PHE A 1 347 ? 173.594 92.516 40.020 1.00 44.13 ? 345 PHE A CG 1 ATOM 2284 C CD1 . PHE A 1 347 ? 174.556 93.070 39.174 1.00 47.55 ? 345 PHE A CD1 1 ATOM 2285 C CD2 . PHE A 1 347 ? 172.945 93.353 40.920 1.00 46.44 ? 345 PHE A CD2 1 ATOM 2286 C CE1 . PHE A 1 347 ? 174.849 94.435 39.221 1.00 48.88 ? 345 PHE A CE1 1 ATOM 2287 C CE2 . PHE A 1 347 ? 173.245 94.721 40.969 1.00 49.41 ? 345 PHE A CE2 1 ATOM 2288 C CZ . PHE A 1 347 ? 174.205 95.249 40.133 1.00 47.50 ? 345 PHE A CZ 1 ATOM 2289 N N . ARG A 1 348 ? 173.632 89.648 42.899 1.00 45.08 ? 346 ARG A N 1 ATOM 2290 C CA . ARG A 1 348 ? 173.553 89.752 44.357 1.00 45.83 ? 346 ARG A CA 1 ATOM 2291 C C . ARG A 1 348 ? 174.908 89.472 44.982 1.00 50.01 ? 346 ARG A C 1 ATOM 2292 O O . ARG A 1 348 ? 175.356 90.220 45.866 1.00 50.47 ? 346 ARG A O 1 ATOM 2293 C CB . ARG A 1 348 ? 172.447 88.842 44.929 1.00 48.79 ? 346 ARG A CB 1 ATOM 2294 C CG . ARG A 1 348 ? 171.029 89.313 44.543 1.00 67.63 ? 346 ARG A CG 1 ATOM 2295 C CD . ARG A 1 348 ? 169.904 88.511 45.185 1.00 84.84 ? 346 ARG A CD 1 ATOM 2296 N NE . ARG A 1 348 ? 169.534 89.028 46.506 1.00 97.85 ? 346 ARG A NE 1 ATOM 2297 C CZ . ARG A 1 348 ? 168.559 89.905 46.729 1.00 110.55 ? 346 ARG A CZ 1 ATOM 2298 N NH1 . ARG A 1 348 ? 168.302 90.319 47.962 1.00 98.95 ? 346 ARG A NH1 1 ATOM 2299 N NH2 . ARG A 1 348 ? 167.837 90.378 45.720 1.00 93.36 ? 346 ARG A NH2 1 ATOM 2300 N N . GLU A 1 349 ? 175.599 88.444 44.454 1.00 45.07 ? 347 GLU A N 1 ATOM 2301 C CA . GLU A 1 349 ? 176.924 88.042 44.903 1.00 43.73 ? 347 GLU A CA 1 ATOM 2302 C C . GLU A 1 349 ? 177.945 89.148 44.635 1.00 45.41 ? 347 GLU A C 1 ATOM 2303 O O . GLU A 1 349 ? 178.744 89.477 45.504 1.00 44.68 ? 347 GLU A O 1 ATOM 2304 C CB . GLU A 1 349 ? 177.317 86.747 44.214 1.00 45.00 ? 347 GLU A CB 1 ATOM 2305 C CG . GLU A 1 349 ? 178.516 86.092 44.866 1.00 57.48 ? 347 GLU A CG 1 ATOM 2306 C CD . GLU A 1 349 ? 178.984 84.851 44.141 1.00 75.64 ? 347 GLU A CD 1 ATOM 2307 O OE1 . GLU A 1 349 ? 180.165 84.476 44.333 1.00 56.56 ? 347 GLU A OE1 1 ATOM 2308 O OE2 . GLU A 1 349 ? 178.199 84.297 43.332 1.00 66.52 ? 347 GLU A OE2 1 ATOM 2309 N N . PHE A 1 350 ? 177.883 89.741 43.452 1.00 41.13 ? 348 PHE A N 1 ATOM 2310 C CA . PHE A 1 350 ? 178.755 90.838 43.080 1.00 40.93 ? 348 PHE A CA 1 ATOM 2311 C C . PHE A 1 350 ? 178.547 92.047 43.989 1.00 45.34 ? 348 PHE A C 1 ATOM 2312 O O . PHE A 1 350 ? 179.534 92.652 44.403 1.00 43.49 ? 348 PHE A O 1 ATOM 2313 C CB . PHE A 1 350 ? 178.545 91.215 41.600 1.00 42.33 ? 348 PHE A CB 1 ATOM 2314 C CG . PHE A 1 350 ? 178.984 92.615 41.237 1.00 43.23 ? 348 PHE A CG 1 ATOM 2315 C CD1 . PHE A 1 350 ? 180.329 92.962 41.238 1.00 45.94 ? 348 PHE A CD1 1 ATOM 2316 C CD2 . PHE A 1 350 ? 178.058 93.577 40.886 1.00 45.87 ? 348 PHE A CD2 1 ATOM 2317 C CE1 . PHE A 1 350 ? 180.736 94.261 40.933 1.00 47.06 ? 348 PHE A CE1 1 ATOM 2318 C CE2 . PHE A 1 350 ? 178.468 94.871 40.556 1.00 49.13 ? 348 PHE A CE2 1 ATOM 2319 C CZ . PHE A 1 350 ? 179.806 95.205 40.583 1.00 46.60 ? 348 PHE A CZ 1 ATOM 2320 N N . TRP A 1 351 ? 177.269 92.411 44.260 1.00 45.13 ? 349 TRP A N 1 ATOM 2321 C CA . TRP A 1 351 ? 176.863 93.559 45.093 1.00 46.36 ? 349 TRP A CA 1 ATOM 2322 C C . TRP A 1 351 ? 177.421 93.443 46.519 1.00 51.24 ? 349 TRP A C 1 ATOM 2323 O O . TRP A 1 351 ? 178.010 94.407 47.036 1.00 50.45 ? 349 TRP A O 1 ATOM 2324 C CB . TRP A 1 351 ? 175.327 93.724 45.102 1.00 45.69 ? 349 TRP A CB 1 ATOM 2325 C CG . TRP A 1 351 ? 174.881 95.059 45.628 1.00 47.28 ? 349 TRP A CG 1 ATOM 2326 C CD1 . TRP A 1 351 ? 174.667 95.399 46.934 1.00 50.27 ? 349 TRP A CD1 1 ATOM 2327 C CD2 . TRP A 1 351 ? 174.655 96.249 44.864 1.00 47.23 ? 349 TRP A CD2 1 ATOM 2328 N NE1 . TRP A 1 351 ? 174.320 96.725 47.028 1.00 49.70 ? 349 TRP A NE1 1 ATOM 2329 C CE2 . TRP A 1 351 ? 174.310 97.273 45.773 1.00 51.38 ? 349 TRP A CE2 1 ATOM 2330 C CE3 . TRP A 1 351 ? 174.726 96.556 43.499 1.00 48.61 ? 349 TRP A CE3 1 ATOM 2331 C CZ2 . TRP A 1 351 ? 174.052 98.582 45.360 1.00 51.03 ? 349 TRP A CZ2 1 ATOM 2332 C CZ3 . TRP A 1 351 ? 174.471 97.855 43.090 1.00 50.43 ? 349 TRP A CZ3 1 ATOM 2333 C CH2 . TRP A 1 351 ? 174.150 98.854 44.015 1.00 51.14 ? 349 TRP A CH2 1 ATOM 2334 N N . GLU A 1 352 ? 177.260 92.238 47.129 1.00 48.20 ? 350 GLU A N 1 ATOM 2335 C CA . GLU A 1 352 ? 177.772 91.888 48.458 1.00 47.73 ? 350 GLU A CA 1 ATOM 2336 C C . GLU A 1 352 ? 179.298 92.013 48.502 1.00 52.09 ? 350 GLU A C 1 ATOM 2337 O O . GLU A 1 352 ? 179.837 92.601 49.434 1.00 52.13 ? 350 GLU A O 1 ATOM 2338 C CB . GLU A 1 352 ? 177.371 90.452 48.826 1.00 48.73 ? 350 GLU A CB 1 ATOM 2339 C CG . GLU A 1 352 ? 175.902 90.277 49.164 1.00 56.90 ? 350 GLU A CG 1 ATOM 2340 C CD . GLU A 1 352 ? 175.408 88.860 49.404 1.00 76.52 ? 350 GLU A CD 1 ATOM 2341 O OE1 . GLU A 1 352 ? 174.212 88.722 49.749 1.00 48.65 ? 350 GLU A OE1 1 ATOM 2342 O OE2 . GLU A 1 352 ? 176.194 87.893 49.250 1.00 79.74 ? 350 GLU A OE2 1 ATOM 2343 N N . GLN A 1 353 ? 179.974 91.464 47.486 1.00 49.38 ? 351 GLN A N 1 ATOM 2344 C CA . GLN A 1 353 ? 181.426 91.444 47.334 1.00 50.15 ? 351 GLN A CA 1 ATOM 2345 C C . GLN A 1 353 ? 182.006 92.843 47.073 1.00 56.05 ? 351 GLN A C 1 ATOM 2346 O O . GLN A 1 353 ? 183.049 93.182 47.638 1.00 57.93 ? 351 GLN A O 1 ATOM 2347 C CB . GLN A 1 353 ? 181.818 90.441 46.230 1.00 51.56 ? 351 GLN A CB 1 ATOM 2348 C CG . GLN A 1 353 ? 183.315 90.235 46.033 1.00 59.13 ? 351 GLN A CG 1 ATOM 2349 C CD . GLN A 1 353 ? 183.603 89.494 44.753 1.00 68.38 ? 351 GLN A CD 1 ATOM 2350 O OE1 . GLN A 1 353 ? 183.701 88.263 44.729 1.00 65.58 ? 351 GLN A OE1 1 ATOM 2351 N NE2 . GLN A 1 353 ? 183.759 90.233 43.663 1.00 49.37 ? 351 GLN A NE2 1 ATOM 2352 N N . ARG A 1 354 ? 181.339 93.652 46.232 1.00 51.08 ? 352 ARG A N 1 ATOM 2353 C CA . ARG A 1 354 ? 181.777 95.008 45.912 1.00 49.68 ? 352 ARG A CA 1 ATOM 2354 C C . ARG A 1 354 ? 181.676 95.953 47.106 1.00 55.26 ? 352 ARG A C 1 ATOM 2355 O O . ARG A 1 354 ? 182.618 96.702 47.357 1.00 54.83 ? 352 ARG A O 1 ATOM 2356 C CB . ARG A 1 354 ? 180.968 95.559 44.725 1.00 46.31 ? 352 ARG A CB 1 ATOM 2357 C CG . ARG A 1 354 ? 181.224 97.036 44.378 1.00 50.55 ? 352 ARG A CG 1 ATOM 2358 C CD . ARG A 1 354 ? 182.633 97.300 43.887 1.00 54.73 ? 352 ARG A CD 1 ATOM 2359 N NE . ARG A 1 354 ? 182.922 98.727 43.775 1.00 67.62 ? 352 ARG A NE 1 ATOM 2360 C CZ . ARG A 1 354 ? 183.389 99.478 44.768 1.00 81.85 ? 352 ARG A CZ 1 ATOM 2361 N NH1 . ARG A 1 354 ? 183.644 100.766 44.570 1.00 67.31 ? 352 ARG A NH1 1 ATOM 2362 N NH2 . ARG A 1 354 ? 183.610 98.946 45.968 1.00 64.82 ? 352 ARG A NH2 1 ATOM 2363 N N . PHE A 1 355 ? 180.530 95.933 47.820 1.00 53.78 ? 353 PHE A N 1 ATOM 2364 C CA . PHE A 1 355 ? 180.246 96.839 48.932 1.00 54.65 ? 353 PHE A CA 1 ATOM 2365 C C . PHE A 1 355 ? 180.566 96.278 50.328 1.00 64.05 ? 353 PHE A C 1 ATOM 2366 O O . PHE A 1 355 ? 180.463 97.012 51.319 1.00 63.62 ? 353 PHE A O 1 ATOM 2367 C CB . PHE A 1 355 ? 178.797 97.323 48.841 1.00 55.81 ? 353 PHE A CB 1 ATOM 2368 C CG . PHE A 1 355 ? 178.556 98.143 47.598 1.00 56.71 ? 353 PHE A CG 1 ATOM 2369 C CD1 . PHE A 1 355 ? 179.195 99.369 47.417 1.00 58.69 ? 353 PHE A CD1 1 ATOM 2370 C CD2 . PHE A 1 355 ? 177.730 97.673 46.584 1.00 58.28 ? 353 PHE A CD2 1 ATOM 2371 C CE1 . PHE A 1 355 ? 178.984 100.122 46.264 1.00 59.12 ? 353 PHE A CE1 1 ATOM 2372 C CE2 . PHE A 1 355 ? 177.526 98.425 45.425 1.00 60.82 ? 353 PHE A CE2 1 ATOM 2373 C CZ . PHE A 1 355 ? 178.149 99.647 45.277 1.00 58.82 ? 353 PHE A CZ 1 ATOM 2374 N N . ARG A 1 356 ? 181.010 95.004 50.391 1.00 64.44 ? 354 ARG A N 1 ATOM 2375 C CA . ARG A 1 356 ? 181.412 94.287 51.610 1.00 65.69 ? 354 ARG A CA 1 ATOM 2376 C C . ARG A 1 356 ? 180.270 94.234 52.657 1.00 74.70 ? 354 ARG A C 1 ATOM 2377 O O . ARG A 1 356 ? 180.502 94.255 53.872 1.00 74.93 ? 354 ARG A O 1 ATOM 2378 C CB . ARG A 1 356 ? 182.744 94.829 52.169 1.00 63.20 ? 354 ARG A CB 1 ATOM 2379 C CG . ARG A 1 356 ? 183.946 94.375 51.332 1.00 71.92 ? 354 ARG A CG 1 ATOM 2380 C CD . ARG A 1 356 ? 185.193 95.195 51.579 1.00 79.20 ? 354 ARG A CD 1 ATOM 2381 N NE . ARG A 1 356 ? 185.104 96.528 50.981 1.00 86.96 ? 354 ARG A NE 1 ATOM 2382 C CZ . ARG A 1 356 ? 185.574 96.848 49.780 1.00 102.98 ? 354 ARG A CZ 1 ATOM 2383 N NH1 . ARG A 1 356 ? 185.448 98.084 49.321 1.00 90.64 ? 354 ARG A NH1 1 ATOM 2384 N NH2 . ARG A 1 356 ? 186.175 95.934 49.028 1.00 93.22 ? 354 ARG A NH2 1 ATOM 2385 N N . CYS A 1 357 ? 179.032 94.107 52.155 1.00 74.08 ? 355 CYS A N 1 ATOM 2386 C CA . CYS A 1 357 ? 177.827 93.991 52.966 1.00 75.33 ? 355 CYS A CA 1 ATOM 2387 C C . CYS A 1 357 ? 177.076 92.722 52.627 1.00 77.25 ? 355 CYS A C 1 ATOM 2388 O O . CYS A 1 357 ? 177.514 91.926 51.797 1.00 75.41 ? 355 CYS A O 1 ATOM 2389 C CB . CYS A 1 357 ? 176.932 95.225 52.831 1.00 77.27 ? 355 CYS A CB 1 ATOM 2390 S SG . CYS A 1 357 ? 176.521 95.691 51.122 1.00 82.15 ? 355 CYS A SG 1 ATOM 2391 N N . SER A 1 358 ? 175.939 92.543 53.291 1.00 74.53 ? 356 SER A N 1 ATOM 2392 C CA . SER A 1 358 ? 175.017 91.436 53.108 1.00 74.45 ? 356 SER A CA 1 ATOM 2393 C C . SER A 1 358 ? 173.620 92.010 53.199 1.00 78.65 ? 356 SER A C 1 ATOM 2394 O O . SER A 1 358 ? 173.388 92.963 53.950 1.00 77.02 ? 356 SER A O 1 ATOM 2395 C CB . SER A 1 358 ? 175.206 90.386 54.203 1.00 76.87 ? 356 SER A CB 1 ATOM 2396 O OG . SER A 1 358 ? 174.409 89.238 53.958 1.00 84.05 ? 356 SER A OG 1 ATOM 2397 N N . PHE A 1 359 ? 172.696 91.438 52.427 1.00 76.93 ? 357 PHE A N 1 ATOM 2398 C CA . PHE A 1 359 ? 171.293 91.830 52.481 1.00 77.89 ? 357 PHE A CA 1 ATOM 2399 C C . PHE A 1 359 ? 170.715 91.281 53.806 1.00 83.62 ? 357 PHE A C 1 ATOM 2400 O O . PHE A 1 359 ? 169.992 91.998 54.504 1.00 83.16 ? 357 PHE A O 1 ATOM 2401 C CB . PHE A 1 359 ? 170.529 91.304 51.247 1.00 79.81 ? 357 PHE A CB 1 ATOM 2402 C CG . PHE A 1 359 ? 171.146 91.663 49.907 1.00 81.15 ? 357 PHE A CG 1 ATOM 2403 C CD1 . PHE A 1 359 ? 171.238 92.990 49.495 1.00 83.80 ? 357 PHE A CD1 1 ATOM 2404 C CD2 . PHE A 1 359 ? 171.598 90.672 49.043 1.00 82.83 ? 357 PHE A CD2 1 ATOM 2405 C CE1 . PHE A 1 359 ? 171.809 93.319 48.262 1.00 84.33 ? 357 PHE A CE1 1 ATOM 2406 C CE2 . PHE A 1 359 ? 172.162 91.004 47.809 1.00 85.34 ? 357 PHE A CE2 1 ATOM 2407 C CZ . PHE A 1 359 ? 172.266 92.325 47.428 1.00 83.18 ? 357 PHE A CZ 1 ATOM 2408 N N . ARG A 1 360 ? 171.127 90.037 54.182 1.00 81.08 ? 358 ARG A N 1 ATOM 2409 C CA . ARG A 1 360 ? 170.766 89.324 55.415 1.00 99.51 ? 358 ARG A CA 1 ATOM 2410 C C . ARG A 1 360 ? 171.555 89.899 56.605 1.00 103.27 ? 358 ARG A C 1 ATOM 2411 O O . ARG A 1 360 ? 171.394 91.069 56.952 1.00 60.71 ? 358 ARG A O 1 ATOM 2412 C CB . ARG A 1 360 ? 171.028 87.808 55.236 1.00 99.19 ? 358 ARG A CB 1 ATOM 2413 C CG . ARG A 1 360 ? 171.137 86.983 56.522 1.00 109.31 ? 358 ARG A CG 1 ATOM 2414 C CD . ARG A 1 360 ? 171.395 85.511 56.231 1.00 120.35 ? 358 ARG A CD 1 ATOM 2415 N NE . ARG A 1 360 ? 172.206 84.865 57.272 1.00 127.51 ? 358 ARG A NE 1 ATOM 2416 C CZ . ARG A 1 360 ? 172.497 83.564 57.308 1.00 137.76 ? 358 ARG A CZ 1 ATOM 2417 N NH1 . ARG A 1 360 ? 173.247 83.074 58.285 1.00 120.57 ? 358 ARG A NH1 1 ATOM 2418 N NH2 . ARG A 1 360 ? 172.038 82.746 56.368 1.00 123.74 ? 358 ARG A NH2 1 ATOM 2419 N N . ARG A 1 362 ? 171.236 93.777 56.293 1.00 94.88 ? 360 ARG A N 1 ATOM 2420 C CA . ARG A 1 362 ? 170.546 95.061 56.138 1.00 95.06 ? 360 ARG A CA 1 ATOM 2421 C C . ARG A 1 362 ? 171.486 96.143 55.579 1.00 97.80 ? 360 ARG A C 1 ATOM 2422 O O . ARG A 1 362 ? 172.704 95.931 55.550 1.00 98.27 ? 360 ARG A O 1 ATOM 2423 C CB . ARG A 1 362 ? 169.971 95.529 57.491 1.00 98.19 ? 360 ARG A CB 1 ATOM 2424 C CG . ARG A 1 362 ? 168.808 94.693 58.024 1.00 114.76 ? 360 ARG A CG 1 ATOM 2425 C CD . ARG A 1 362 ? 168.331 95.202 59.378 1.00 128.77 ? 360 ARG A CD 1 ATOM 2426 N NE . ARG A 1 362 ? 167.364 94.294 60.006 1.00 137.21 ? 360 ARG A NE 1 ATOM 2427 C CZ . ARG A 1 362 ? 167.651 93.445 60.990 1.00 147.45 ? 360 ARG A CZ 1 ATOM 2428 N NH1 . ARG A 1 362 ? 168.883 93.379 61.483 1.00 133.31 ? 360 ARG A NH1 1 ATOM 2429 N NH2 . ARG A 1 362 ? 166.707 92.661 61.494 1.00 130.79 ? 360 ARG A NH2 1 ATOM 2430 N N . ASP A 1 363 ? 170.913 97.304 55.136 1.00 92.05 ? 361 ASP A N 1 ATOM 2431 C CA . ASP A 1 363 ? 171.604 98.504 54.612 1.00 90.53 ? 361 ASP A CA 1 ATOM 2432 C C . ASP A 1 363 ? 172.556 98.260 53.388 1.00 90.16 ? 361 ASP A C 1 ATOM 2433 O O . ASP A 1 363 ? 173.271 99.178 52.974 1.00 89.92 ? 361 ASP A O 1 ATOM 2434 C CB . ASP A 1 363 ? 172.356 99.228 55.752 1.00 92.67 ? 361 ASP A CB 1 ATOM 2435 C CG . ASP A 1 363 ? 172.466 100.734 55.603 1.00 104.22 ? 361 ASP A CG 1 ATOM 2436 O OD1 . ASP A 1 363 ? 171.416 101.393 55.418 1.00 105.78 ? 361 ASP A OD1 1 ATOM 2437 O OD2 . ASP A 1 363 ? 173.595 101.263 55.733 1.00 108.27 ? 361 ASP A OD2 1 ATOM 2438 N N . CYS A 1 364 ? 172.544 97.048 52.801 1.00 82.42 ? 362 CYS A N 1 ATOM 2439 C CA . CYS A 1 364 ? 173.346 96.729 51.619 1.00 80.15 ? 362 CYS A CA 1 ATOM 2440 C C . CYS A 1 364 ? 172.693 97.447 50.427 1.00 82.36 ? 362 CYS A C 1 ATOM 2441 O O . CYS A 1 364 ? 173.382 98.063 49.608 1.00 81.55 ? 362 CYS A O 1 ATOM 2442 C CB . CYS A 1 364 ? 173.408 95.216 51.410 1.00 79.45 ? 362 CYS A CB 1 ATOM 2443 S SG . CYS A 1 364 ? 174.882 94.621 50.523 1.00 82.60 ? 362 CYS A SG 1 ATOM 2444 N N . ALA A 1 365 ? 171.346 97.448 50.412 1.00 77.78 ? 363 ALA A N 1 ATOM 2445 C CA . ALA A 1 365 ? 170.483 98.106 49.430 1.00 77.05 ? 363 ALA A CA 1 ATOM 2446 C C . ALA A 1 365 ? 170.735 99.624 49.301 1.00 78.01 ? 363 ALA A C 1 ATOM 2447 O O . ALA A 1 365 ? 170.391 100.197 48.266 1.00 78.11 ? 363 ALA A O 1 ATOM 2448 C CB . ALA A 1 365 ? 169.031 97.868 49.801 1.00 78.02 ? 363 ALA A CB 1 ATOM 2449 N N . ALA A 1 366 ? 171.316 100.261 50.347 1.00 71.74 ? 364 ALA A N 1 ATOM 2450 C CA . ALA A 1 366 ? 171.624 101.699 50.420 1.00 70.51 ? 364 ALA A CA 1 ATOM 2451 C C . ALA A 1 366 ? 172.693 102.168 49.433 1.00 70.88 ? 364 ALA A C 1 ATOM 2452 O O . ALA A 1 366 ? 172.711 103.350 49.066 1.00 71.07 ? 364 ALA A O 1 ATOM 2453 C CB . ALA A 1 366 ? 172.044 102.072 51.837 1.00 71.38 ? 364 ALA A CB 1 ATOM 2454 N N . HIS A 1 367 ? 173.593 101.251 49.030 1.00 63.69 ? 365 HIS A N 1 ATOM 2455 C CA . HIS A 1 367 ? 174.702 101.514 48.112 1.00 61.17 ? 365 HIS A CA 1 ATOM 2456 C C . HIS A 1 367 ? 174.284 101.806 46.670 1.00 58.82 ? 365 HIS A C 1 ATOM 2457 O O . HIS A 1 367 ? 173.191 101.432 46.237 1.00 56.26 ? 365 HIS A O 1 ATOM 2458 C CB . HIS A 1 367 ? 175.696 100.353 48.149 1.00 61.91 ? 365 HIS A CB 1 ATOM 2459 C CG . HIS A 1 367 ? 176.334 100.153 49.485 1.00 65.28 ? 365 HIS A CG 1 ATOM 2460 N ND1 . HIS A 1 367 ? 177.284 101.037 49.972 1.00 66.97 ? 365 HIS A ND1 1 ATOM 2461 C CD2 . HIS A 1 367 ? 176.147 99.168 50.393 1.00 66.92 ? 365 HIS A CD2 1 ATOM 2462 C CE1 . HIS A 1 367 ? 177.646 100.557 51.150 1.00 66.36 ? 365 HIS A CE1 1 ATOM 2463 N NE2 . HIS A 1 367 ? 176.989 99.434 51.447 1.00 66.68 ? 365 HIS A NE2 1 ATOM 2464 N N . SER A 1 368 ? 175.163 102.503 45.941 1.00 53.56 ? 366 SER A N 1 ATOM 2465 C CA . SER A 1 368 ? 174.972 102.846 44.537 1.00 52.47 ? 366 SER A CA 1 ATOM 2466 C C . SER A 1 368 ? 176.284 102.763 43.785 1.00 53.68 ? 366 SER A C 1 ATOM 2467 O O . SER A 1 368 ? 177.319 103.248 44.269 1.00 51.86 ? 366 SER A O 1 ATOM 2468 C CB . SER A 1 368 ? 174.379 104.247 44.369 1.00 56.11 ? 366 SER A CB 1 ATOM 2469 O OG . SER A 1 368 ? 174.166 104.579 43.002 1.00 63.17 ? 366 SER A OG 1 ATOM 2470 N N . LEU A 1 369 ? 176.206 102.183 42.563 1.00 48.92 ? 367 LEU A N 1 ATOM 2471 C CA . LEU A 1 369 ? 177.301 102.077 41.602 1.00 48.04 ? 367 LEU A CA 1 ATOM 2472 C C . LEU A 1 369 ? 177.628 103.477 41.009 1.00 54.23 ? 367 LEU A C 1 ATOM 2473 O O . LEU A 1 369 ? 178.698 103.647 40.410 1.00 53.23 ? 367 LEU A O 1 ATOM 2474 C CB . LEU A 1 369 ? 177.008 101.032 40.495 1.00 46.91 ? 367 LEU A CB 1 ATOM 2475 C CG . LEU A 1 369 ? 176.855 99.558 40.907 1.00 49.56 ? 367 LEU A CG 1 ATOM 2476 C CD1 . LEU A 1 369 ? 176.573 98.696 39.725 1.00 49.32 ? 367 LEU A CD1 1 ATOM 2477 C CD2 . LEU A 1 369 ? 178.084 99.028 41.595 1.00 50.18 ? 367 LEU A CD2 1 ATOM 2478 N N . ARG A 1 370 ? 176.720 104.480 41.226 1.00 52.47 ? 368 ARG A N 1 ATOM 2479 C CA . ARG A 1 370 ? 176.911 105.888 40.841 1.00 52.96 ? 368 ARG A CA 1 ATOM 2480 C C . ARG A 1 370 ? 177.829 106.574 41.872 1.00 57.64 ? 368 ARG A C 1 ATOM 2481 O O . ARG A 1 370 ? 178.642 107.430 41.504 1.00 57.42 ? 368 ARG A O 1 ATOM 2482 C CB . ARG A 1 370 ? 175.572 106.645 40.795 1.00 52.20 ? 368 ARG A CB 1 ATOM 2483 C CG . ARG A 1 370 ? 174.719 106.377 39.567 1.00 59.73 ? 368 ARG A CG 1 ATOM 2484 C CD . ARG A 1 370 ? 173.268 106.178 39.971 1.00 68.05 ? 368 ARG A CD 1 ATOM 2485 N NE . ARG A 1 370 ? 172.342 106.458 38.873 1.00 75.43 ? 368 ARG A NE 1 ATOM 2486 C CZ . ARG A 1 370 ? 171.096 105.999 38.797 1.00 92.17 ? 368 ARG A CZ 1 ATOM 2487 N NH1 . ARG A 1 370 ? 170.610 105.212 39.751 1.00 85.23 ? 368 ARG A NH1 1 ATOM 2488 N NH2 . ARG A 1 370 ? 170.333 106.306 37.758 1.00 77.00 ? 368 ARG A NH2 1 ATOM 2489 N N . ALA A 1 371 ? 177.684 106.188 43.160 1.00 54.29 ? 369 ALA A N 1 ATOM 2490 C CA . ALA A 1 371 ? 178.435 106.716 44.309 1.00 54.32 ? 369 ALA A CA 1 ATOM 2491 C C . ALA A 1 371 ? 179.908 106.297 44.326 1.00 57.76 ? 369 ALA A C 1 ATOM 2492 O O . ALA A 1 371 ? 180.718 106.929 45.004 1.00 57.99 ? 369 ALA A O 1 ATOM 2493 C CB . ALA A 1 371 ? 177.770 106.260 45.598 1.00 55.12 ? 369 ALA A CB 1 ATOM 2494 N N . VAL A 1 372 ? 180.228 105.199 43.626 1.00 52.48 ? 370 VAL A N 1 ATOM 2495 C CA . VAL A 1 372 ? 181.538 104.571 43.526 1.00 50.31 ? 370 VAL A CA 1 ATOM 2496 C C . VAL A 1 372 ? 182.183 104.883 42.160 1.00 51.42 ? 370 VAL A C 1 ATOM 2497 O O . VAL A 1 372 ? 181.451 105.147 41.206 1.00 50.83 ? 370 VAL A O 1 ATOM 2498 C CB . VAL A 1 372 ? 181.350 103.046 43.717 1.00 53.35 ? 370 VAL A CB 1 ATOM 2499 N N . PRO A 1 373 ? 183.533 104.832 42.012 1.00 46.61 ? 371 PRO A N 1 ATOM 2500 C CA . PRO A 1 373 ? 184.121 105.061 40.678 1.00 46.11 ? 371 PRO A CA 1 ATOM 2501 C C . PRO A 1 373 ? 183.926 103.874 39.716 1.00 48.77 ? 371 PRO A C 1 ATOM 2502 O O . PRO A 1 373 ? 184.121 102.725 40.113 1.00 49.36 ? 371 PRO A O 1 ATOM 2503 C CB . PRO A 1 373 ? 185.605 105.307 40.980 1.00 47.80 ? 371 PRO A CB 1 ATOM 2504 C CG . PRO A 1 373 ? 185.865 104.656 42.286 1.00 51.55 ? 371 PRO A CG 1 ATOM 2505 C CD . PRO A 1 373 ? 184.572 104.523 43.023 1.00 47.44 ? 371 PRO A CD 1 ATOM 2506 N N . PHE A 1 374 ? 183.524 104.151 38.458 1.00 43.62 ? 372 PHE A N 1 ATOM 2507 C CA . PHE A 1 374 ? 183.317 103.131 37.413 1.00 42.36 ? 372 PHE A CA 1 ATOM 2508 C C . PHE A 1 374 ? 184.352 103.246 36.285 1.00 44.29 ? 372 PHE A C 1 ATOM 2509 O O . PHE A 1 374 ? 184.387 104.256 35.573 1.00 44.24 ? 372 PHE A O 1 ATOM 2510 C CB . PHE A 1 374 ? 181.879 103.182 36.819 1.00 43.37 ? 372 PHE A CB 1 ATOM 2511 C CG . PHE A 1 374 ? 181.614 102.273 35.623 1.00 43.90 ? 372 PHE A CG 1 ATOM 2512 C CD1 . PHE A 1 374 ? 181.170 100.968 35.800 1.00 45.76 ? 372 PHE A CD1 1 ATOM 2513 C CD2 . PHE A 1 374 ? 181.784 102.736 34.319 1.00 44.56 ? 372 PHE A CD2 1 ATOM 2514 C CE1 . PHE A 1 374 ? 180.919 100.141 34.694 1.00 45.89 ? 372 PHE A CE1 1 ATOM 2515 C CE2 . PHE A 1 374 ? 181.554 101.894 33.220 1.00 45.87 ? 372 PHE A CE2 1 ATOM 2516 C CZ . PHE A 1 374 ? 181.092 100.617 33.414 1.00 43.58 ? 372 PHE A CZ 1 ATOM 2517 N N . GLU A 1 375 ? 185.126 102.175 36.074 1.00 38.08 ? 373 GLU A N 1 ATOM 2518 C CA . GLU A 1 375 ? 186.081 102.098 34.981 1.00 35.82 ? 373 GLU A CA 1 ATOM 2519 C C . GLU A 1 375 ? 185.617 100.934 34.078 1.00 36.54 ? 373 GLU A C 1 ATOM 2520 O O . GLU A 1 375 ? 185.549 99.775 34.519 1.00 36.58 ? 373 GLU A O 1 ATOM 2521 C CB . GLU A 1 375 ? 187.511 101.938 35.528 1.00 36.90 ? 373 GLU A CB 1 ATOM 2522 N N . GLN A 1 376 ? 185.273 101.243 32.844 1.00 29.75 ? 374 GLN A N 1 ATOM 2523 C CA . GLN A 1 376 ? 184.751 100.279 31.899 1.00 27.72 ? 374 GLN A CA 1 ATOM 2524 C C . GLN A 1 376 ? 185.806 99.306 31.461 1.00 30.85 ? 374 GLN A C 1 ATOM 2525 O O . GLN A 1 376 ? 186.898 99.679 31.205 1.00 31.36 ? 374 GLN A O 1 ATOM 2526 C CB . GLN A 1 376 ? 184.200 101.008 30.687 1.00 28.52 ? 374 GLN A CB 1 ATOM 2527 C CG . GLN A 1 376 ? 183.427 100.178 29.691 1.00 37.17 ? 374 GLN A CG 1 ATOM 2528 C CD . GLN A 1 376 ? 182.888 100.981 28.540 1.00 59.53 ? 374 GLN A CD 1 ATOM 2529 O OE1 . GLN A 1 376 ? 182.137 101.904 28.730 1.00 50.07 ? 374 GLN A OE1 1 ATOM 2530 N NE2 . GLN A 1 376 ? 183.255 100.630 27.353 1.00 58.40 ? 374 GLN A NE2 1 ATOM 2531 N N . GLU A 1 377 ? 185.457 98.043 31.381 1.00 26.51 ? 375 GLU A N 1 ATOM 2532 C CA . GLU A 1 377 ? 186.391 97.002 30.984 1.00 25.41 ? 375 GLU A CA 1 ATOM 2533 C C . GLU A 1 377 ? 186.832 97.212 29.535 1.00 30.26 ? 375 GLU A C 1 ATOM 2534 O O . GLU A 1 377 ? 186.016 97.626 28.707 1.00 31.26 ? 375 GLU A O 1 ATOM 2535 C CB . GLU A 1 377 ? 185.748 95.627 31.224 1.00 26.56 ? 375 GLU A CB 1 ATOM 2536 C CG . GLU A 1 377 ? 186.734 94.476 31.229 1.00 36.67 ? 375 GLU A CG 1 ATOM 2537 C CD . GLU A 1 377 ? 187.067 93.962 29.843 1.00 48.46 ? 375 GLU A CD 1 ATOM 2538 O OE1 . GLU A 1 377 ? 186.121 93.762 29.046 1.00 38.83 ? 375 GLU A OE1 1 ATOM 2539 O OE2 . GLU A 1 377 ? 188.273 93.850 29.522 1.00 26.55 ? 375 GLU A OE2 1 ATOM 2540 N N . SER A 1 378 ? 188.131 96.953 29.235 1.00 26.19 ? 376 SER A N 1 ATOM 2541 C CA . SER A 1 378 ? 188.727 97.117 27.897 1.00 24.98 ? 376 SER A CA 1 ATOM 2542 C C . SER A 1 378 ? 187.978 96.480 26.743 1.00 28.98 ? 376 SER A C 1 ATOM 2543 O O . SER A 1 378 ? 187.892 97.090 25.687 1.00 29.31 ? 376 SER A O 1 ATOM 2544 C CB . SER A 1 378 ? 190.162 96.614 27.875 1.00 28.76 ? 376 SER A CB 1 ATOM 2545 O OG . SER A 1 378 ? 191.079 97.550 28.414 1.00 42.53 ? 376 SER A OG 1 ATOM 2546 N N . LYS A 1 379 ? 187.457 95.262 26.924 1.00 26.28 ? 377 LYS A N 1 ATOM 2547 C CA . LYS A 1 379 ? 186.791 94.500 25.869 1.00 26.06 ? 377 LYS A CA 1 ATOM 2548 C C . LYS A 1 379 ? 185.255 94.631 25.790 1.00 31.81 ? 377 LYS A C 1 ATOM 2549 O O . LYS A 1 379 ? 184.650 93.919 24.977 1.00 32.72 ? 377 LYS A O 1 ATOM 2550 C CB . LYS A 1 379 ? 187.177 93.027 25.981 1.00 27.95 ? 377 LYS A CB 1 ATOM 2551 C CG . LYS A 1 379 ? 188.263 92.610 25.015 1.00 31.72 ? 377 LYS A CG 1 ATOM 2552 C CD . LYS A 1 379 ? 189.373 91.985 25.765 1.00 32.99 ? 377 LYS A CD 1 ATOM 2553 C CE . LYS A 1 379 ? 190.391 91.405 24.858 1.00 31.55 ? 377 LYS A CE 1 ATOM 2554 N NZ . LYS A 1 379 ? 191.670 91.292 25.574 1.00 37.36 ? 377 LYS A NZ 1 ATOM 2555 N N . ILE A 1 380 ? 184.624 95.546 26.576 1.00 27.52 ? 378 ILE A N 1 ATOM 2556 C CA . ILE A 1 380 ? 183.158 95.757 26.541 1.00 27.02 ? 378 ILE A CA 1 ATOM 2557 C C . ILE A 1 380 ? 182.625 95.927 25.082 1.00 32.91 ? 378 ILE A C 1 ATOM 2558 O O . ILE A 1 380 ? 181.635 95.287 24.715 1.00 32.53 ? 378 ILE A O 1 ATOM 2559 C CB . ILE A 1 380 ? 182.689 96.903 27.501 1.00 28.25 ? 378 ILE A CB 1 ATOM 2560 C CG1 . ILE A 1 380 ? 182.839 96.508 28.984 1.00 27.01 ? 378 ILE A CG1 1 ATOM 2561 C CG2 . ILE A 1 380 ? 181.261 97.375 27.194 1.00 27.82 ? 378 ILE A CG2 1 ATOM 2562 C CD1 . ILE A 1 380 ? 182.270 95.180 29.392 1.00 24.91 ? 378 ILE A CD1 1 ATOM 2563 N N . MET A 1 381 ? 183.299 96.764 24.286 1.00 31.54 ? 379 MET A N 1 ATOM 2564 C CA . MET A 1 381 ? 183.045 97.039 22.876 1.00 33.76 ? 379 MET A CA 1 ATOM 2565 C C . MET A 1 381 ? 182.749 95.771 22.094 1.00 32.73 ? 379 MET A C 1 ATOM 2566 O O . MET A 1 381 ? 181.762 95.693 21.370 1.00 31.47 ? 379 MET A O 1 ATOM 2567 C CB . MET A 1 381 ? 184.346 97.535 22.278 1.00 38.79 ? 379 MET A CB 1 ATOM 2568 C CG . MET A 1 381 ? 184.403 98.958 22.035 1.00 46.55 ? 379 MET A CG 1 ATOM 2569 S SD . MET A 1 381 ? 185.581 99.116 20.711 1.00 54.50 ? 379 MET A SD 1 ATOM 2570 C CE . MET A 1 381 ? 184.401 99.254 19.309 1.00 52.44 ? 379 MET A CE 1 ATOM 2571 N N . PHE A 1 382 ? 183.678 94.802 22.198 1.00 25.57 ? 380 PHE A N 1 ATOM 2572 C CA . PHE A 1 382 ? 183.668 93.539 21.490 1.00 23.51 ? 380 PHE A CA 1 ATOM 2573 C C . PHE A 1 382 ? 182.558 92.634 21.923 1.00 24.96 ? 380 PHE A C 1 ATOM 2574 O O . PHE A 1 382 ? 182.137 91.802 21.126 1.00 25.47 ? 380 PHE A O 1 ATOM 2575 C CB . PHE A 1 382 ? 185.019 92.849 21.623 1.00 24.77 ? 380 PHE A CB 1 ATOM 2576 C CG . PHE A 1 382 ? 186.151 93.791 21.349 1.00 25.82 ? 380 PHE A CG 1 ATOM 2577 C CD1 . PHE A 1 382 ? 186.376 94.278 20.065 1.00 29.30 ? 380 PHE A CD1 1 ATOM 2578 C CD2 . PHE A 1 382 ? 186.939 94.264 22.382 1.00 28.17 ? 380 PHE A CD2 1 ATOM 2579 C CE1 . PHE A 1 382 ? 187.407 95.181 19.815 1.00 30.20 ? 380 PHE A CE1 1 ATOM 2580 C CE2 . PHE A 1 382 ? 187.977 95.168 22.136 1.00 31.62 ? 380 PHE A CE2 1 ATOM 2581 C CZ . PHE A 1 382 ? 188.198 95.627 20.854 1.00 29.77 ? 380 PHE A CZ 1 ATOM 2582 N N . VAL A 1 383 ? 182.059 92.822 23.160 1.00 18.62 ? 381 VAL A N 1 ATOM 2583 C CA . VAL A 1 383 ? 180.944 92.064 23.708 1.00 18.92 ? 381 VAL A CA 1 ATOM 2584 C C . VAL A 1 383 ? 179.699 92.521 22.953 1.00 24.13 ? 381 VAL A C 1 ATOM 2585 O O . VAL A 1 383 ? 179.089 91.725 22.218 1.00 24.79 ? 381 VAL A O 1 ATOM 2586 C CB . VAL A 1 383 ? 180.839 92.153 25.266 1.00 22.79 ? 381 VAL A CB 1 ATOM 2587 C CG1 . VAL A 1 383 ? 179.732 91.233 25.790 1.00 22.82 ? 381 VAL A CG1 1 ATOM 2588 C CG2 . VAL A 1 383 ? 182.186 91.809 25.937 1.00 21.59 ? 381 VAL A CG2 1 ATOM 2589 N N . VAL A 1 384 ? 179.442 93.835 23.012 1.00 19.56 ? 382 VAL A N 1 ATOM 2590 C CA . VAL A 1 384 ? 178.385 94.550 22.315 1.00 19.19 ? 382 VAL A CA 1 ATOM 2591 C C . VAL A 1 384 ? 178.471 94.289 20.811 1.00 24.59 ? 382 VAL A C 1 ATOM 2592 O O . VAL A 1 384 ? 177.454 93.964 20.208 1.00 27.52 ? 382 VAL A O 1 ATOM 2593 C CB . VAL A 1 384 ? 178.414 96.066 22.700 1.00 23.28 ? 382 VAL A CB 1 ATOM 2594 C CG1 . VAL A 1 384 ? 177.345 96.875 21.940 1.00 23.17 ? 382 VAL A CG1 1 ATOM 2595 C CG2 . VAL A 1 384 ? 178.231 96.233 24.207 1.00 22.38 ? 382 VAL A CG2 1 ATOM 2596 N N . ASN A 1 385 ? 179.665 94.342 20.215 1.00 21.14 ? 383 ASN A N 1 ATOM 2597 C CA . ASN A 1 385 ? 179.836 94.036 18.782 1.00 21.56 ? 383 ASN A CA 1 ATOM 2598 C C . ASN A 1 385 ? 179.524 92.586 18.427 1.00 26.14 ? 383 ASN A C 1 ATOM 2599 O O . ASN A 1 385 ? 178.976 92.359 17.360 1.00 26.55 ? 383 ASN A O 1 ATOM 2600 C CB . ASN A 1 385 ? 181.231 94.395 18.285 1.00 25.28 ? 383 ASN A CB 1 ATOM 2601 C CG . ASN A 1 385 ? 181.516 95.886 18.232 1.00 41.62 ? 383 ASN A CG 1 ATOM 2602 O OD1 . ASN A 1 385 ? 180.612 96.720 18.168 1.00 28.22 ? 383 ASN A OD1 1 ATOM 2603 N ND2 . ASN A 1 385 ? 182.789 96.255 18.197 1.00 31.77 ? 383 ASN A ND2 1 ATOM 2604 N N . ALA A 1 386 ? 179.858 91.603 19.307 1.00 21.65 ? 384 ALA A N 1 ATOM 2605 C CA . ALA A 1 386 ? 179.564 90.193 19.053 1.00 19.95 ? 384 ALA A CA 1 ATOM 2606 C C . ALA A 1 386 ? 178.060 89.974 18.987 1.00 24.75 ? 384 ALA A C 1 ATOM 2607 O O . ALA A 1 386 ? 177.585 89.307 18.068 1.00 23.65 ? 384 ALA A O 1 ATOM 2608 C CB . ALA A 1 386 ? 180.157 89.328 20.145 1.00 20.50 ? 384 ALA A CB 1 ATOM 2609 N N . VAL A 1 387 ? 177.296 90.562 19.946 1.00 22.79 ? 385 VAL A N 1 ATOM 2610 C CA . VAL A 1 387 ? 175.837 90.444 19.983 1.00 22.49 ? 385 VAL A CA 1 ATOM 2611 C C . VAL A 1 387 ? 175.266 91.108 18.736 1.00 28.62 ? 385 VAL A C 1 ATOM 2612 O O . VAL A 1 387 ? 174.473 90.477 18.030 1.00 30.30 ? 385 VAL A O 1 ATOM 2613 C CB . VAL A 1 387 ? 175.169 91.002 21.259 1.00 26.24 ? 385 VAL A CB 1 ATOM 2614 C CG1 . VAL A 1 387 ? 173.755 90.448 21.401 1.00 25.93 ? 385 VAL A CG1 1 ATOM 2615 C CG2 . VAL A 1 387 ? 175.993 90.716 22.516 1.00 25.66 ? 385 VAL A CG2 1 ATOM 2616 N N . TYR A 1 388 ? 175.702 92.340 18.415 1.00 23.72 ? 386 TYR A N 1 ATOM 2617 C CA . TYR A 1 388 ? 175.183 92.994 17.209 1.00 23.46 ? 386 TYR A CA 1 ATOM 2618 C C . TYR A 1 388 ? 175.544 92.215 15.952 1.00 27.78 ? 386 TYR A C 1 ATOM 2619 O O . TYR A 1 388 ? 174.694 92.063 15.079 1.00 29.73 ? 386 TYR A O 1 ATOM 2620 C CB . TYR A 1 388 ? 175.589 94.481 17.131 1.00 24.99 ? 386 TYR A CB 1 ATOM 2621 C CG . TYR A 1 388 ? 174.709 95.390 17.963 1.00 26.26 ? 386 TYR A CG 1 ATOM 2622 C CD1 . TYR A 1 388 ? 174.836 95.444 19.348 1.00 27.89 ? 386 TYR A CD1 1 ATOM 2623 C CD2 . TYR A 1 388 ? 173.743 96.196 17.365 1.00 27.02 ? 386 TYR A CD2 1 ATOM 2624 C CE1 . TYR A 1 388 ? 173.999 96.250 20.120 1.00 29.18 ? 386 TYR A CE1 1 ATOM 2625 C CE2 . TYR A 1 388 ? 172.900 97.003 18.127 1.00 26.72 ? 386 TYR A CE2 1 ATOM 2626 C CZ . TYR A 1 388 ? 173.027 97.020 19.501 1.00 35.28 ? 386 TYR A CZ 1 ATOM 2627 O OH . TYR A 1 388 ? 172.169 97.792 20.234 1.00 41.68 ? 386 TYR A OH 1 ATOM 2628 N N . ALA A 1 389 ? 176.751 91.631 15.881 1.00 23.04 ? 387 ALA A N 1 ATOM 2629 C CA . ALA A 1 389 ? 177.120 90.819 14.711 1.00 22.04 ? 387 ALA A CA 1 ATOM 2630 C C . ALA A 1 389 ? 176.124 89.657 14.533 1.00 26.66 ? 387 ALA A C 1 ATOM 2631 O O . ALA A 1 389 ? 175.611 89.516 13.426 1.00 26.01 ? 387 ALA A O 1 ATOM 2632 C CB . ALA A 1 389 ? 178.545 90.316 14.824 1.00 22.32 ? 387 ALA A CB 1 ATOM 2633 N N . MET A 1 390 ? 175.737 88.939 15.634 1.00 22.98 ? 388 MET A N 1 ATOM 2634 C CA . MET A 1 390 ? 174.731 87.875 15.563 1.00 24.16 ? 388 MET A CA 1 ATOM 2635 C C . MET A 1 390 ? 173.320 88.402 15.159 1.00 31.65 ? 388 MET A C 1 ATOM 2636 O O . MET A 1 390 ? 172.621 87.762 14.365 1.00 32.06 ? 388 MET A O 1 ATOM 2637 C CB . MET A 1 390 ? 174.639 87.113 16.896 1.00 26.88 ? 388 MET A CB 1 ATOM 2638 C CG . MET A 1 390 ? 174.011 85.740 16.752 1.00 31.06 ? 388 MET A CG 1 ATOM 2639 S SD . MET A 1 390 ? 175.077 84.547 15.886 1.00 36.54 ? 388 MET A SD 1 ATOM 2640 C CE . MET A 1 390 ? 176.147 83.982 17.279 1.00 34.04 ? 388 MET A CE 1 ATOM 2641 N N . ALA A 1 391 ? 172.912 89.554 15.721 1.00 28.70 ? 389 ALA A N 1 ATOM 2642 C CA . ALA A 1 391 ? 171.619 90.197 15.483 1.00 28.66 ? 389 ALA A CA 1 ATOM 2643 C C . ALA A 1 391 ? 171.485 90.666 14.040 1.00 35.15 ? 389 ALA A C 1 ATOM 2644 O O . ALA A 1 391 ? 170.449 90.424 13.414 1.00 36.45 ? 389 ALA A O 1 ATOM 2645 C CB . ALA A 1 391 ? 171.436 91.359 16.444 1.00 29.28 ? 389 ALA A CB 1 ATOM 2646 N N . HIS A 1 392 ? 172.551 91.279 13.491 1.00 31.11 ? 390 HIS A N 1 ATOM 2647 C CA . HIS A 1 392 ? 172.596 91.734 12.104 1.00 30.19 ? 390 HIS A CA 1 ATOM 2648 C C . HIS A 1 392 ? 172.630 90.547 11.191 1.00 35.00 ? 390 HIS A C 1 ATOM 2649 O O . HIS A 1 392 ? 172.043 90.609 10.130 1.00 35.60 ? 390 HIS A O 1 ATOM 2650 C CB . HIS A 1 392 ? 173.829 92.600 11.854 1.00 30.78 ? 390 HIS A CB 1 ATOM 2651 C CG . HIS A 1 392 ? 173.645 94.039 12.209 1.00 33.89 ? 390 HIS A CG 1 ATOM 2652 N ND1 . HIS A 1 392 ? 173.322 94.983 11.246 1.00 35.13 ? 390 HIS A ND1 1 ATOM 2653 C CD2 . HIS A 1 392 ? 173.758 94.658 13.404 1.00 35.90 ? 390 HIS A CD2 1 ATOM 2654 C CE1 . HIS A 1 392 ? 173.262 96.138 11.883 1.00 34.68 ? 390 HIS A CE1 1 ATOM 2655 N NE2 . HIS A 1 392 ? 173.509 95.999 13.182 1.00 35.44 ? 390 HIS A NE2 1 ATOM 2656 N N . ALA A 1 393 ? 173.313 89.456 11.591 1.00 32.96 ? 391 ALA A N 1 ATOM 2657 C CA . ALA A 1 393 ? 173.389 88.226 10.798 1.00 33.11 ? 391 ALA A CA 1 ATOM 2658 C C . ALA A 1 393 ? 172.010 87.624 10.656 1.00 36.46 ? 391 ALA A C 1 ATOM 2659 O O . ALA A 1 393 ? 171.621 87.253 9.550 1.00 37.44 ? 391 ALA A O 1 ATOM 2660 C CB . ALA A 1 393 ? 174.312 87.229 11.465 1.00 34.09 ? 391 ALA A CB 1 ATOM 2661 N N . LEU A 1 394 ? 171.261 87.565 11.773 1.00 30.83 ? 392 LEU A N 1 ATOM 2662 C CA . LEU A 1 394 ? 169.901 87.032 11.844 1.00 29.29 ? 392 LEU A CA 1 ATOM 2663 C C . LEU A 1 394 ? 168.904 87.884 11.086 1.00 35.44 ? 392 LEU A C 1 ATOM 2664 O O . LEU A 1 394 ? 168.064 87.338 10.361 1.00 37.03 ? 392 LEU A O 1 ATOM 2665 C CB . LEU A 1 394 ? 169.473 86.824 13.310 1.00 27.93 ? 392 LEU A CB 1 ATOM 2666 C CG . LEU A 1 394 ? 170.134 85.613 13.979 1.00 29.30 ? 392 LEU A CG 1 ATOM 2667 C CD1 . LEU A 1 394 ? 170.097 85.729 15.458 1.00 28.75 ? 392 LEU A CD1 1 ATOM 2668 C CD2 . LEU A 1 394 ? 169.572 84.283 13.445 1.00 26.58 ? 392 LEU A CD2 1 ATOM 2669 N N . HIS A 1 395 ? 169.040 89.215 11.189 1.00 30.97 ? 393 HIS A N 1 ATOM 2670 C CA . HIS A 1 395 ? 168.180 90.180 10.513 1.00 30.59 ? 393 HIS A CA 1 ATOM 2671 C C . HIS A 1 395 ? 168.356 90.078 9.005 1.00 34.10 ? 393 HIS A C 1 ATOM 2672 O O . HIS A 1 395 ? 167.390 90.130 8.255 1.00 35.10 ? 393 HIS A O 1 ATOM 2673 C CB . HIS A 1 395 ? 168.509 91.581 11.033 1.00 32.15 ? 393 HIS A CB 1 ATOM 2674 C CG . HIS A 1 395 ? 167.777 92.701 10.365 1.00 36.02 ? 393 HIS A CG 1 ATOM 2675 N ND1 . HIS A 1 395 ? 166.636 93.252 10.925 1.00 37.95 ? 393 HIS A ND1 1 ATOM 2676 C CD2 . HIS A 1 395 ? 168.081 93.378 9.237 1.00 37.09 ? 393 HIS A CD2 1 ATOM 2677 C CE1 . HIS A 1 395 ? 166.276 94.223 10.109 1.00 36.81 ? 393 HIS A CE1 1 ATOM 2678 N NE2 . HIS A 1 395 ? 167.131 94.357 9.098 1.00 36.88 ? 393 HIS A NE2 1 ATOM 2679 N N . ASN A 1 396 ? 169.585 89.901 8.559 1.00 30.07 ? 394 ASN A N 1 ATOM 2680 C CA . ASN A 1 396 ? 169.873 89.775 7.145 1.00 29.78 ? 394 ASN A CA 1 ATOM 2681 C C . ASN A 1 396 ? 169.369 88.479 6.634 1.00 36.14 ? 394 ASN A C 1 ATOM 2682 O O . ASN A 1 396 ? 168.944 88.419 5.476 1.00 37.24 ? 394 ASN A O 1 ATOM 2683 C CB . ASN A 1 396 ? 171.363 89.874 6.883 1.00 28.75 ? 394 ASN A CB 1 ATOM 2684 C CG . ASN A 1 396 ? 171.951 91.209 7.202 1.00 35.35 ? 394 ASN A CG 1 ATOM 2685 O OD1 . ASN A 1 396 ? 171.253 92.163 7.557 1.00 32.94 ? 394 ASN A OD1 1 ATOM 2686 N ND2 . ASN A 1 396 ? 173.265 91.268 7.190 1.00 26.64 ? 394 ASN A ND2 1 ATOM 2687 N N . MET A 1 397 ? 169.450 87.418 7.481 1.00 33.81 ? 395 MET A N 1 ATOM 2688 C CA . MET A 1 397 ? 168.976 86.089 7.123 1.00 33.65 ? 395 MET A CA 1 ATOM 2689 C C . MET A 1 397 ? 167.456 86.185 6.930 1.00 41.34 ? 395 MET A C 1 ATOM 2690 O O . MET A 1 397 ? 166.927 85.729 5.911 1.00 41.10 ? 395 MET A O 1 ATOM 2691 C CB . MET A 1 397 ? 169.328 85.055 8.187 1.00 34.82 ? 395 MET A CB 1 ATOM 2692 C CG . MET A 1 397 ? 168.968 83.664 7.737 1.00 37.83 ? 395 MET A CG 1 ATOM 2693 S SD . MET A 1 397 ? 169.505 82.320 8.812 1.00 41.40 ? 395 MET A SD 1 ATOM 2694 C CE . MET A 1 397 ? 169.637 80.973 7.611 1.00 37.89 ? 395 MET A CE 1 ATOM 2695 N N . HIS A 1 398 ? 166.785 86.863 7.886 1.00 38.15 ? 396 HIS A N 1 ATOM 2696 C CA . HIS A 1 398 ? 165.357 87.087 7.869 1.00 37.81 ? 396 HIS A CA 1 ATOM 2697 C C . HIS A 1 398 ? 164.954 87.869 6.625 1.00 40.44 ? 396 HIS A C 1 ATOM 2698 O O . HIS A 1 398 ? 163.962 87.537 6.026 1.00 38.16 ? 396 HIS A O 1 ATOM 2699 C CB . HIS A 1 398 ? 164.904 87.782 9.162 1.00 38.93 ? 396 HIS A CB 1 ATOM 2700 C CG . HIS A 1 398 ? 163.418 87.913 9.248 1.00 42.74 ? 396 HIS A CG 1 ATOM 2701 N ND1 . HIS A 1 398 ? 162.735 88.894 8.532 1.00 44.65 ? 396 HIS A ND1 1 ATOM 2702 C CD2 . HIS A 1 398 ? 162.520 87.151 9.908 1.00 44.31 ? 396 HIS A CD2 1 ATOM 2703 C CE1 . HIS A 1 398 ? 161.455 88.707 8.801 1.00 43.81 ? 396 HIS A CE1 1 ATOM 2704 N NE2 . HIS A 1 398 ? 161.277 87.685 9.635 1.00 44.27 ? 396 HIS A NE2 1 ATOM 2705 N N . ARG A 1 399 ? 165.723 88.881 6.228 1.00 40.20 ? 397 ARG A N 1 ATOM 2706 C CA . ARG A 1 399 ? 165.433 89.667 5.028 1.00 40.64 ? 397 ARG A CA 1 ATOM 2707 C C . ARG A 1 399 ? 165.446 88.769 3.780 1.00 43.00 ? 397 ARG A C 1 ATOM 2708 O O . ARG A 1 399 ? 164.505 88.811 3.004 1.00 42.65 ? 397 ARG A O 1 ATOM 2709 C CB . ARG A 1 399 ? 166.398 90.857 4.926 1.00 42.41 ? 397 ARG A CB 1 ATOM 2710 C CG . ARG A 1 399 ? 166.188 91.761 3.712 1.00 59.67 ? 397 ARG A CG 1 ATOM 2711 C CD . ARG A 1 399 ? 166.950 93.076 3.838 1.00 79.14 ? 397 ARG A CD 1 ATOM 2712 N NE . ARG A 1 399 ? 168.408 92.891 3.855 1.00 91.62 ? 397 ARG A NE 1 ATOM 2713 C CZ . ARG A 1 399 ? 169.203 93.204 4.878 1.00 101.78 ? 397 ARG A CZ 1 ATOM 2714 N NH1 . ARG A 1 399 ? 170.512 93.001 4.794 1.00 87.86 ? 397 ARG A NH1 1 ATOM 2715 N NH2 . ARG A 1 399 ? 168.697 93.733 5.986 1.00 82.03 ? 397 ARG A NH2 1 ATOM 2716 N N . ALA A 1 400 ? 166.445 87.896 3.653 1.00 39.62 ? 398 ALA A N 1 ATOM 2717 C CA . ALA A 1 400 ? 166.549 86.962 2.537 1.00 39.69 ? 398 ALA A CA 1 ATOM 2718 C C . ALA A 1 400 ? 165.491 85.858 2.575 1.00 46.95 ? 398 ALA A C 1 ATOM 2719 O O . ALA A 1 400 ? 164.806 85.642 1.582 1.00 48.20 ? 398 ALA A O 1 ATOM 2720 C CB . ALA A 1 400 ? 167.937 86.345 2.498 1.00 39.95 ? 398 ALA A CB 1 ATOM 2721 N N . LEU A 1 401 ? 165.341 85.180 3.716 1.00 43.70 ? 399 LEU A N 1 ATOM 2722 C CA . LEU A 1 401 ? 164.454 84.036 3.846 1.00 43.78 ? 399 LEU A CA 1 ATOM 2723 C C . LEU A 1 401 ? 162.980 84.334 4.155 1.00 49.99 ? 399 LEU A C 1 ATOM 2724 O O . LEU A 1 401 ? 162.121 83.586 3.683 1.00 49.78 ? 399 LEU A O 1 ATOM 2725 C CB . LEU A 1 401 ? 165.013 83.051 4.885 1.00 43.50 ? 399 LEU A CB 1 ATOM 2726 C CG . LEU A 1 401 ? 166.409 82.452 4.650 1.00 47.45 ? 399 LEU A CG 1 ATOM 2727 C CD1 . LEU A 1 401 ? 166.631 81.300 5.553 1.00 47.21 ? 399 LEU A CD1 1 ATOM 2728 C CD2 . LEU A 1 401 ? 166.588 81.952 3.230 1.00 49.82 ? 399 LEU A CD2 1 ATOM 2729 N N . CYS A 1 402 ? 162.682 85.361 4.956 1.00 48.31 ? 400 CYS A N 1 ATOM 2730 C CA . CYS A 1 402 ? 161.311 85.685 5.357 1.00 50.04 ? 400 CYS A CA 1 ATOM 2731 C C . CYS A 1 402 ? 160.843 87.042 4.801 1.00 54.60 ? 400 CYS A C 1 ATOM 2732 O O . CYS A 1 402 ? 160.674 87.976 5.584 1.00 52.60 ? 400 CYS A O 1 ATOM 2733 C CB . CYS A 1 402 ? 161.187 85.632 6.876 1.00 51.89 ? 400 CYS A CB 1 ATOM 2734 S SG . CYS A 1 402 ? 162.001 84.211 7.643 1.00 56.91 ? 400 CYS A SG 1 ATOM 2735 N N . PRO A 1 403 ? 160.592 87.192 3.479 1.00 54.81 ? 401 PRO A N 1 ATOM 2736 C CA . PRO A 1 403 ? 160.217 88.523 2.967 1.00 56.22 ? 401 PRO A CA 1 ATOM 2737 C C . PRO A 1 403 ? 158.754 88.940 3.172 1.00 64.53 ? 401 PRO A C 1 ATOM 2738 O O . PRO A 1 403 ? 158.468 90.134 3.276 1.00 64.70 ? 401 PRO A O 1 ATOM 2739 C CB . PRO A 1 403 ? 160.592 88.442 1.486 1.00 57.46 ? 401 PRO A CB 1 ATOM 2740 C CG . PRO A 1 403 ? 160.448 87.000 1.141 1.00 61.05 ? 401 PRO A CG 1 ATOM 2741 C CD . PRO A 1 403 ? 160.707 86.204 2.381 1.00 56.33 ? 401 PRO A CD 1 ATOM 2742 N N . ASN A 1 404 ? 157.837 87.973 3.238 1.00 63.63 ? 402 ASN A N 1 ATOM 2743 C CA . ASN A 1 404 ? 156.410 88.257 3.377 1.00 64.70 ? 402 ASN A CA 1 ATOM 2744 C C . ASN A 1 404 ? 155.976 88.664 4.815 1.00 68.74 ? 402 ASN A C 1 ATOM 2745 O O . ASN A 1 404 ? 154.814 89.038 5.015 1.00 70.30 ? 402 ASN A O 1 ATOM 2746 C CB . ASN A 1 404 ? 155.576 87.060 2.849 1.00 67.76 ? 402 ASN A CB 1 ATOM 2747 C CG . ASN A 1 404 ? 155.702 86.800 1.350 1.00 96.89 ? 402 ASN A CG 1 ATOM 2748 O OD1 . ASN A 1 404 ? 155.336 87.633 0.501 1.00 92.89 ? 402 ASN A OD1 1 ATOM 2749 N ND2 . ASN A 1 404 ? 156.182 85.613 0.989 1.00 86.41 ? 402 ASN A ND2 1 ATOM 2750 N N . THR A 1 405 ? 156.893 88.598 5.806 1.00 61.73 ? 403 THR A N 1 ATOM 2751 C CA . THR A 1 405 ? 156.580 88.888 7.211 1.00 59.23 ? 403 THR A CA 1 ATOM 2752 C C . THR A 1 405 ? 157.744 89.586 7.961 1.00 59.65 ? 403 THR A C 1 ATOM 2753 O O . THR A 1 405 ? 158.759 89.937 7.355 1.00 58.88 ? 403 THR A O 1 ATOM 2754 C CB . THR A 1 405 ? 156.110 87.581 7.887 1.00 65.89 ? 403 THR A CB 1 ATOM 2755 O OG1 . THR A 1 405 ? 155.606 87.843 9.197 1.00 66.14 ? 403 THR A OG1 1 ATOM 2756 C CG2 . THR A 1 405 ? 157.193 86.481 7.916 1.00 64.97 ? 403 THR A CG2 1 ATOM 2757 N N . THR A 1 406 ? 157.544 89.849 9.264 1.00 54.61 ? 404 THR A N 1 ATOM 2758 C CA . THR A 1 406 ? 158.533 90.423 10.187 1.00 53.54 ? 404 THR A CA 1 ATOM 2759 C C . THR A 1 406 ? 158.720 89.444 11.325 1.00 54.90 ? 404 THR A C 1 ATOM 2760 O O . THR A 1 406 ? 159.589 89.636 12.176 1.00 55.65 ? 404 THR A O 1 ATOM 2761 C CB . THR A 1 406 ? 158.142 91.814 10.708 1.00 61.21 ? 404 THR A CB 1 ATOM 2762 O OG1 . THR A 1 406 ? 156.962 91.731 11.512 1.00 58.38 ? 404 THR A OG1 1 ATOM 2763 C CG2 . THR A 1 406 ? 158.017 92.846 9.602 1.00 60.38 ? 404 THR A CG2 1 ATOM 2764 N N . ARG A 1 407 ? 157.874 88.404 11.343 1.00 48.20 ? 405 ARG A N 1 ATOM 2765 C CA . ARG A 1 407 ? 157.883 87.325 12.318 1.00 46.61 ? 405 ARG A CA 1 ATOM 2766 C C . ARG A 1 407 ? 158.741 86.192 11.743 1.00 47.21 ? 405 ARG A C 1 ATOM 2767 O O . ARG A 1 407 ? 159.060 86.237 10.560 1.00 45.60 ? 405 ARG A O 1 ATOM 2768 C CB . ARG A 1 407 ? 156.441 86.870 12.595 1.00 46.50 ? 405 ARG A CB 1 ATOM 2769 N N . LEU A 1 408 ? 159.153 85.207 12.566 1.00 43.75 ? 406 LEU A N 1 ATOM 2770 C CA . LEU A 1 408 ? 159.982 84.089 12.095 1.00 43.47 ? 406 LEU A CA 1 ATOM 2771 C C . LEU A 1 408 ? 159.196 83.213 11.147 1.00 48.51 ? 406 LEU A C 1 ATOM 2772 O O . LEU A 1 408 ? 158.219 82.608 11.567 1.00 47.93 ? 406 LEU A O 1 ATOM 2773 C CB . LEU A 1 408 ? 160.493 83.225 13.270 1.00 43.18 ? 406 LEU A CB 1 ATOM 2774 C CG . LEU A 1 408 ? 161.719 83.692 14.040 1.00 46.69 ? 406 LEU A CG 1 ATOM 2775 C CD1 . LEU A 1 408 ? 162.020 82.732 15.164 1.00 46.83 ? 406 LEU A CD1 1 ATOM 2776 C CD2 . LEU A 1 408 ? 162.927 83.823 13.138 1.00 47.21 ? 406 LEU A CD2 1 ATOM 2777 N N . CYS A 1 409 ? 159.610 83.140 9.882 1.00 48.30 ? 407 CYS A N 1 ATOM 2778 C CA . CYS A 1 409 ? 158.931 82.319 8.876 1.00 50.49 ? 407 CYS A CA 1 ATOM 2779 C C . CYS A 1 409 ? 159.335 80.855 9.051 1.00 54.09 ? 407 CYS A C 1 ATOM 2780 O O . CYS A 1 409 ? 160.095 80.555 9.964 1.00 53.49 ? 407 CYS A O 1 ATOM 2781 C CB . CYS A 1 409 ? 159.215 82.833 7.464 1.00 52.56 ? 407 CYS A CB 1 ATOM 2782 S SG . CYS A 1 409 ? 160.941 82.611 6.920 1.00 57.74 ? 407 CYS A SG 1 ATOM 2783 N N . ASP A 1 410 ? 158.816 79.944 8.205 1.00 51.79 ? 408 ASP A N 1 ATOM 2784 C CA . ASP A 1 410 ? 159.105 78.505 8.287 1.00 51.41 ? 408 ASP A CA 1 ATOM 2785 C C . ASP A 1 410 ? 160.555 78.189 7.987 1.00 53.90 ? 408 ASP A C 1 ATOM 2786 O O . ASP A 1 410 ? 161.144 77.352 8.682 1.00 53.62 ? 408 ASP A O 1 ATOM 2787 C CB . ASP A 1 410 ? 158.156 77.692 7.401 1.00 53.67 ? 408 ASP A CB 1 ATOM 2788 C CG . ASP A 1 410 ? 156.704 77.743 7.838 1.00 67.98 ? 408 ASP A CG 1 ATOM 2789 O OD1 . ASP A 1 410 ? 156.449 77.745 9.074 1.00 70.56 ? 408 ASP A OD1 1 ATOM 2790 O OD2 . ASP A 1 410 ? 155.820 77.807 6.951 1.00 71.92 ? 408 ASP A OD2 1 ATOM 2791 N N . ALA A 1 411 ? 161.155 78.925 7.008 1.00 48.95 ? 409 ALA A N 1 ATOM 2792 C CA . ALA A 1 411 ? 162.578 78.841 6.624 1.00 47.29 ? 409 ALA A CA 1 ATOM 2793 C C . ALA A 1 411 ? 163.511 79.113 7.820 1.00 50.74 ? 409 ALA A C 1 ATOM 2794 O O . ALA A 1 411 ? 164.682 78.743 7.777 1.00 52.03 ? 409 ALA A O 1 ATOM 2795 C CB . ALA A 1 411 ? 162.880 79.821 5.501 1.00 47.51 ? 409 ALA A CB 1 ATOM 2796 N N . MET A 1 412 ? 162.988 79.731 8.890 1.00 44.94 ? 410 MET A N 1 ATOM 2797 C CA . MET A 1 412 ? 163.766 80.016 10.080 1.00 43.84 ? 410 MET A CA 1 ATOM 2798 C C . MET A 1 412 ? 163.206 79.311 11.310 1.00 47.61 ? 410 MET A C 1 ATOM 2799 O O . MET A 1 412 ? 163.487 79.715 12.432 1.00 46.54 ? 410 MET A O 1 ATOM 2800 C CB . MET A 1 412 ? 163.940 81.525 10.259 1.00 46.04 ? 410 MET A CB 1 ATOM 2801 C CG . MET A 1 412 ? 165.000 82.094 9.299 1.00 49.40 ? 410 MET A CG 1 ATOM 2802 S SD . MET A 1 412 ? 165.250 83.885 9.350 1.00 52.94 ? 410 MET A SD 1 ATOM 2803 C CE . MET A 1 412 ? 166.063 84.062 10.923 1.00 48.97 ? 410 MET A CE 1 ATOM 2804 N N . ARG A 1 413 ? 162.479 78.190 11.097 1.00 45.37 ? 411 ARG A N 1 ATOM 2805 C CA . ARG A 1 413 ? 161.911 77.348 12.167 1.00 44.49 ? 411 ARG A CA 1 ATOM 2806 C C . ARG A 1 413 ? 162.321 75.881 11.910 1.00 48.83 ? 411 ARG A C 1 ATOM 2807 O O . ARG A 1 413 ? 161.561 75.115 11.304 1.00 48.92 ? 411 ARG A O 1 ATOM 2808 C CB . ARG A 1 413 ? 160.379 77.494 12.288 1.00 41.02 ? 411 ARG A CB 1 ATOM 2809 C CG . ARG A 1 413 ? 159.907 78.818 12.848 1.00 44.76 ? 411 ARG A CG 1 ATOM 2810 C CD . ARG A 1 413 ? 158.391 78.871 12.964 1.00 54.18 ? 411 ARG A CD 1 ATOM 2811 N NE . ARG A 1 413 ? 157.960 80.219 13.329 1.00 68.50 ? 411 ARG A NE 1 ATOM 2812 C CZ . ARG A 1 413 ? 157.757 80.632 14.577 1.00 85.53 ? 411 ARG A CZ 1 ATOM 2813 N NH1 . ARG A 1 413 ? 157.885 79.787 15.594 1.00 72.04 ? 411 ARG A NH1 1 ATOM 2814 N NH2 . ARG A 1 413 ? 157.408 81.893 14.818 1.00 70.51 ? 411 ARG A NH2 1 ATOM 2815 N N . PRO A 1 414 ? 163.553 75.488 12.314 1.00 44.37 ? 412 PRO A N 1 ATOM 2816 C CA . PRO A 1 414 ? 164.562 76.290 13.029 1.00 43.06 ? 412 PRO A CA 1 ATOM 2817 C C . PRO A 1 414 ? 165.506 77.011 12.069 1.00 44.26 ? 412 PRO A C 1 ATOM 2818 O O . PRO A 1 414 ? 165.407 76.827 10.852 1.00 43.15 ? 412 PRO A O 1 ATOM 2819 C CB . PRO A 1 414 ? 165.287 75.229 13.862 1.00 44.29 ? 412 PRO A CB 1 ATOM 2820 C CG . PRO A 1 414 ? 165.267 74.003 12.981 1.00 48.61 ? 412 PRO A CG 1 ATOM 2821 C CD . PRO A 1 414 ? 164.035 74.108 12.096 1.00 44.66 ? 412 PRO A CD 1 ATOM 2822 N N . VAL A 1 415 ? 166.421 77.833 12.623 1.00 39.12 ? 413 VAL A N 1 ATOM 2823 C CA . VAL A 1 415 ? 167.440 78.529 11.840 1.00 37.08 ? 413 VAL A CA 1 ATOM 2824 C C . VAL A 1 415 ? 168.536 77.500 11.507 1.00 39.68 ? 413 VAL A C 1 ATOM 2825 O O . VAL A 1 415 ? 169.024 76.816 12.410 1.00 39.64 ? 413 VAL A O 1 ATOM 2826 C CB . VAL A 1 415 ? 168.024 79.745 12.606 1.00 39.78 ? 413 VAL A CB 1 ATOM 2827 C CG1 . VAL A 1 415 ? 169.207 80.359 11.867 1.00 39.27 ? 413 VAL A CG1 1 ATOM 2828 C CG2 . VAL A 1 415 ? 166.960 80.792 12.881 1.00 39.67 ? 413 VAL A CG2 1 ATOM 2829 N N . ASN A 1 416 ? 168.909 77.395 10.226 1.00 34.65 ? 414 ASN A N 1 ATOM 2830 C CA . ASN A 1 416 ? 169.998 76.528 9.792 1.00 33.84 ? 414 ASN A CA 1 ATOM 2831 C C . ASN A 1 416 ? 171.311 77.247 10.111 1.00 38.02 ? 414 ASN A C 1 ATOM 2832 O O . ASN A 1 416 ? 171.616 78.293 9.503 1.00 39.82 ? 414 ASN A O 1 ATOM 2833 C CB . ASN A 1 416 ? 169.910 76.231 8.280 1.00 30.64 ? 414 ASN A CB 1 ATOM 2834 C CG . ASN A 1 416 ? 170.955 75.257 7.829 1.00 49.96 ? 414 ASN A CG 1 ATOM 2835 O OD1 . ASN A 1 416 ? 172.018 75.629 7.346 1.00 48.67 ? 414 ASN A OD1 1 ATOM 2836 N ND2 . ASN A 1 416 ? 170.707 73.983 8.049 1.00 49.39 ? 414 ASN A ND2 1 ATOM 2837 N N . GLY A 1 417 ? 172.052 76.693 11.065 1.00 31.72 ? 415 GLY A N 1 ATOM 2838 C CA . GLY A 1 417 ? 173.344 77.207 11.515 1.00 30.11 ? 415 GLY A CA 1 ATOM 2839 C C . GLY A 1 417 ? 174.412 77.268 10.442 1.00 32.93 ? 415 GLY A C 1 ATOM 2840 O O . GLY A 1 417 ? 175.163 78.252 10.387 1.00 33.13 ? 415 GLY A O 1 ATOM 2841 N N . ARG A 1 418 ? 174.475 76.241 9.552 1.00 28.93 ? 416 ARG A N 1 ATOM 2842 C CA . ARG A 1 418 ? 175.451 76.238 8.455 1.00 28.98 ? 416 ARG A CA 1 ATOM 2843 C C . ARG A 1 418 ? 175.235 77.469 7.563 1.00 33.67 ? 416 ARG A C 1 ATOM 2844 O O . ARG A 1 418 ? 176.197 78.200 7.317 1.00 32.09 ? 416 ARG A O 1 ATOM 2845 C CB . ARG A 1 418 ? 175.395 74.944 7.633 1.00 29.69 ? 416 ARG A CB 1 ATOM 2846 C CG . ARG A 1 418 ? 176.636 74.734 6.771 1.00 41.92 ? 416 ARG A CG 1 ATOM 2847 C CD . ARG A 1 418 ? 176.365 73.947 5.500 1.00 64.50 ? 416 ARG A CD 1 ATOM 2848 N NE . ARG A 1 418 ? 177.585 73.817 4.695 1.00 87.29 ? 416 ARG A NE 1 ATOM 2849 C CZ . ARG A 1 418 ? 177.686 73.131 3.557 1.00 104.50 ? 416 ARG A CZ 1 ATOM 2850 N NH1 . ARG A 1 418 ? 176.629 72.498 3.056 1.00 94.88 ? 416 ARG A NH1 1 ATOM 2851 N NH2 . ARG A 1 418 ? 178.845 73.076 2.909 1.00 86.76 ? 416 ARG A NH2 1 ATOM 2852 N N . ARG A 1 419 ? 173.959 77.730 7.157 1.00 32.05 ? 417 ARG A N 1 ATOM 2853 C CA . ARG A 1 419 ? 173.536 78.884 6.345 1.00 32.78 ? 417 ARG A CA 1 ATOM 2854 C C . ARG A 1 419 ? 173.800 80.178 7.115 1.00 32.41 ? 417 ARG A C 1 ATOM 2855 O O . ARG A 1 419 ? 174.355 81.136 6.558 1.00 30.76 ? 417 ARG A O 1 ATOM 2856 C CB . ARG A 1 419 ? 172.022 78.819 6.008 1.00 38.53 ? 417 ARG A CB 1 ATOM 2857 C CG . ARG A 1 419 ? 171.570 77.881 4.864 1.00 55.15 ? 417 ARG A CG 1 ATOM 2858 C CD . ARG A 1 419 ? 171.868 78.384 3.456 1.00 75.62 ? 417 ARG A CD 1 ATOM 2859 N NE . ARG A 1 419 ? 171.501 79.788 3.189 1.00 81.11 ? 417 ARG A NE 1 ATOM 2860 C CZ . ARG A 1 419 ? 170.337 80.190 2.681 1.00 86.60 ? 417 ARG A CZ 1 ATOM 2861 N NH1 . ARG A 1 419 ? 169.363 79.314 2.448 1.00 70.63 ? 417 ARG A NH1 1 ATOM 2862 N NH2 . ARG A 1 419 ? 170.127 81.473 2.427 1.00 67.59 ? 417 ARG A NH2 1 ATOM 2863 N N . LEU A 1 420 ? 173.408 80.194 8.395 1.00 26.10 ? 418 LEU A N 1 ATOM 2864 C CA . LEU A 1 420 ? 173.583 81.369 9.230 1.00 26.24 ? 418 LEU A CA 1 ATOM 2865 C C . LEU A 1 420 ? 175.030 81.824 9.294 1.00 33.49 ? 418 LEU A C 1 ATOM 2866 O O . LEU A 1 420 ? 175.297 83.010 9.079 1.00 34.61 ? 418 LEU A O 1 ATOM 2867 C CB . LEU A 1 420 ? 173.023 81.156 10.659 1.00 25.84 ? 418 LEU A CB 1 ATOM 2868 C CG . LEU A 1 420 ? 173.114 82.370 11.590 1.00 28.76 ? 418 LEU A CG 1 ATOM 2869 C CD1 . LEU A 1 420 ? 172.306 83.558 11.042 1.00 27.22 ? 418 LEU A CD1 1 ATOM 2870 C CD2 . LEU A 1 420 ? 172.762 81.991 13.019 1.00 29.87 ? 418 LEU A CD2 1 ATOM 2871 N N . TYR A 1 421 ? 175.962 80.892 9.598 1.00 29.08 ? 419 TYR A N 1 ATOM 2872 C CA . TYR A 1 421 ? 177.372 81.242 9.724 1.00 27.37 ? 419 TYR A CA 1 ATOM 2873 C C . TYR A 1 421 ? 178.007 81.608 8.399 1.00 33.92 ? 419 TYR A C 1 ATOM 2874 O O . TYR A 1 421 ? 178.580 82.699 8.276 1.00 34.29 ? 419 TYR A O 1 ATOM 2875 C CB . TYR A 1 421 ? 178.142 80.105 10.404 1.00 26.04 ? 419 TYR A CB 1 ATOM 2876 C CG . TYR A 1 421 ? 179.626 80.367 10.499 1.00 23.27 ? 419 TYR A CG 1 ATOM 2877 C CD1 . TYR A 1 421 ? 180.487 80.000 9.462 1.00 23.57 ? 419 TYR A CD1 1 ATOM 2878 C CD2 . TYR A 1 421 ? 180.176 80.978 11.623 1.00 23.73 ? 419 TYR A CD2 1 ATOM 2879 C CE1 . TYR A 1 421 ? 181.849 80.270 9.523 1.00 20.32 ? 419 TYR A CE1 1 ATOM 2880 C CE2 . TYR A 1 421 ? 181.549 81.222 11.709 1.00 25.47 ? 419 TYR A CE2 1 ATOM 2881 C CZ . TYR A 1 421 ? 182.379 80.859 10.654 1.00 28.77 ? 419 TYR A CZ 1 ATOM 2882 O OH . TYR A 1 421 ? 183.721 81.077 10.705 1.00 29.86 ? 419 TYR A OH 1 ATOM 2883 N N . LYS A 1 422 ? 177.951 80.667 7.432 1.00 31.24 ? 420 LYS A N 1 ATOM 2884 C CA . LYS A 1 422 ? 178.567 80.812 6.123 1.00 31.40 ? 420 LYS A CA 1 ATOM 2885 C C . LYS A 1 422 ? 178.010 81.938 5.291 1.00 37.11 ? 420 LYS A C 1 ATOM 2886 O O . LYS A 1 422 ? 178.796 82.635 4.647 1.00 39.70 ? 420 LYS A O 1 ATOM 2887 C CB . LYS A 1 422 ? 178.536 79.500 5.326 1.00 32.35 ? 420 LYS A CB 1 ATOM 2888 N N . ASP A 1 423 ? 176.688 82.130 5.274 1.00 32.05 ? 421 ASP A N 1 ATOM 2889 C CA . ASP A 1 423 ? 176.124 83.152 4.384 1.00 31.68 ? 421 ASP A CA 1 ATOM 2890 C C . ASP A 1 423 ? 175.784 84.503 5.018 1.00 35.40 ? 421 ASP A C 1 ATOM 2891 O O . ASP A 1 423 ? 175.657 85.485 4.284 1.00 36.64 ? 421 ASP A O 1 ATOM 2892 C CB . ASP A 1 423 ? 174.892 82.607 3.659 1.00 33.57 ? 421 ASP A CB 1 ATOM 2893 C CG . ASP A 1 423 ? 175.113 81.325 2.866 1.00 48.97 ? 421 ASP A CG 1 ATOM 2894 O OD1 . ASP A 1 423 ? 176.264 81.091 2.398 1.00 51.81 ? 421 ASP A OD1 1 ATOM 2895 O OD2 . ASP A 1 423 ? 174.133 80.571 2.678 1.00 51.62 ? 421 ASP A OD2 1 ATOM 2896 N N . PHE A 1 424 ? 175.639 84.572 6.347 1.00 29.91 ? 422 PHE A N 1 ATOM 2897 C CA . PHE A 1 424 ? 175.239 85.813 6.977 1.00 29.24 ? 422 PHE A CA 1 ATOM 2898 C C . PHE A 1 424 ? 176.216 86.324 8.054 1.00 35.61 ? 422 PHE A C 1 ATOM 2899 O O . PHE A 1 424 ? 176.592 87.504 8.010 1.00 37.12 ? 422 PHE A O 1 ATOM 2900 C CB . PHE A 1 424 ? 173.799 85.690 7.509 1.00 29.89 ? 422 PHE A CB 1 ATOM 2901 C CG . PHE A 1 424 ? 172.850 85.335 6.392 1.00 30.64 ? 422 PHE A CG 1 ATOM 2902 C CD1 . PHE A 1 424 ? 172.408 86.308 5.495 1.00 33.45 ? 422 PHE A CD1 1 ATOM 2903 C CD2 . PHE A 1 424 ? 172.473 84.011 6.170 1.00 31.66 ? 422 PHE A CD2 1 ATOM 2904 C CE1 . PHE A 1 424 ? 171.569 85.968 4.428 1.00 33.13 ? 422 PHE A CE1 1 ATOM 2905 C CE2 . PHE A 1 424 ? 171.652 83.669 5.092 1.00 33.38 ? 422 PHE A CE2 1 ATOM 2906 C CZ . PHE A 1 424 ? 171.215 84.646 4.225 1.00 31.69 ? 422 PHE A CZ 1 ATOM 2907 N N . VAL A 1 425 ? 176.624 85.469 9.001 1.00 31.38 ? 423 VAL A N 1 ATOM 2908 C CA . VAL A 1 425 ? 177.558 85.874 10.062 1.00 31.06 ? 423 VAL A CA 1 ATOM 2909 C C . VAL A 1 425 ? 178.866 86.406 9.460 1.00 36.70 ? 423 VAL A C 1 ATOM 2910 O O . VAL A 1 425 ? 179.289 87.517 9.790 1.00 36.83 ? 423 VAL A O 1 ATOM 2911 C CB . VAL A 1 425 ? 177.797 84.779 11.128 1.00 32.97 ? 423 VAL A CB 1 ATOM 2912 C CG1 . VAL A 1 425 ? 178.906 85.185 12.094 1.00 31.75 ? 423 VAL A CG1 1 ATOM 2913 C CG2 . VAL A 1 425 ? 176.516 84.476 11.885 1.00 32.49 ? 423 VAL A CG2 1 ATOM 2914 N N . LEU A 1 426 ? 179.446 85.652 8.519 1.00 33.51 ? 424 LEU A N 1 ATOM 2915 C CA . LEU A 1 426 ? 180.701 86.039 7.875 1.00 33.03 ? 424 LEU A CA 1 ATOM 2916 C C . LEU A 1 426 ? 180.610 87.298 7.010 1.00 35.65 ? 424 LEU A C 1 ATOM 2917 O O . LEU A 1 426 ? 181.642 87.927 6.712 1.00 33.11 ? 424 LEU A O 1 ATOM 2918 C CB . LEU A 1 426 ? 181.256 84.859 7.052 1.00 32.27 ? 424 LEU A CB 1 ATOM 2919 C CG . LEU A 1 426 ? 182.033 83.801 7.829 1.00 34.17 ? 424 LEU A CG 1 ATOM 2920 C CD1 . LEU A 1 426 ? 182.532 82.738 6.906 1.00 32.94 ? 424 LEU A CD1 1 ATOM 2921 C CD2 . LEU A 1 426 ? 183.192 84.417 8.627 1.00 33.51 ? 424 LEU A CD2 1 ATOM 2922 N N . ASN A 1 427 ? 179.366 87.663 6.639 1.00 32.05 ? 425 ASN A N 1 ATOM 2923 C CA . ASN A 1 427 ? 179.087 88.751 5.719 1.00 31.29 ? 425 ASN A CA 1 ATOM 2924 C C . ASN A 1 427 ? 178.513 90.023 6.326 1.00 32.97 ? 425 ASN A C 1 ATOM 2925 O O . ASN A 1 427 ? 178.291 90.981 5.581 1.00 33.06 ? 425 ASN A O 1 ATOM 2926 C CB . ASN A 1 427 ? 178.195 88.244 4.621 1.00 29.85 ? 425 ASN A CB 1 ATOM 2927 C CG . ASN A 1 427 ? 178.936 87.308 3.725 1.00 52.77 ? 425 ASN A CG 1 ATOM 2928 O OD1 . ASN A 1 427 ? 180.125 87.509 3.461 1.00 48.25 ? 425 ASN A OD1 1 ATOM 2929 N ND2 . ASN A 1 427 ? 178.265 86.248 3.263 1.00 45.79 ? 425 ASN A ND2 1 ATOM 2930 N N . VAL A 1 428 ? 178.315 90.070 7.652 1.00 26.50 ? 426 VAL A N 1 ATOM 2931 C CA . VAL A 1 428 ? 177.836 91.294 8.287 1.00 25.86 ? 426 VAL A CA 1 ATOM 2932 C C . VAL A 1 428 ? 178.871 92.386 8.017 1.00 31.22 ? 426 VAL A C 1 ATOM 2933 O O . VAL A 1 428 ? 180.033 92.071 7.794 1.00 31.72 ? 426 VAL A O 1 ATOM 2934 C CB . VAL A 1 428 ? 177.537 91.157 9.817 1.00 28.64 ? 426 VAL A CB 1 ATOM 2935 C CG1 . VAL A 1 428 ? 176.517 90.065 10.094 1.00 28.13 ? 426 VAL A CG1 1 ATOM 2936 C CG2 . VAL A 1 428 ? 178.810 90.942 10.636 1.00 27.81 ? 426 VAL A CG2 1 ATOM 2937 N N . LYS A 1 429 ? 178.444 93.649 7.999 1.00 28.65 ? 427 LYS A N 1 ATOM 2938 C CA . LYS A 1 429 ? 179.281 94.841 7.812 1.00 28.28 ? 427 LYS A CA 1 ATOM 2939 C C . LYS A 1 429 ? 178.389 96.008 8.249 1.00 35.21 ? 427 LYS A C 1 ATOM 2940 O O . LYS A 1 429 ? 177.406 96.326 7.580 1.00 36.44 ? 427 LYS A O 1 ATOM 2941 C CB . LYS A 1 429 ? 179.761 94.983 6.364 1.00 28.84 ? 427 LYS A CB 1 ATOM 2942 C CG . LYS A 1 429 ? 180.873 96.018 6.196 1.00 46.39 ? 427 LYS A CG 1 ATOM 2943 C CD . LYS A 1 429 ? 181.443 96.030 4.769 1.00 54.44 ? 427 LYS A CD 1 ATOM 2944 C CE . LYS A 1 429 ? 180.780 97.017 3.845 1.00 65.65 ? 427 LYS A CE 1 ATOM 2945 N NZ . LYS A 1 429 ? 181.336 96.924 2.463 1.00 81.45 ? 427 LYS A NZ 1 ATOM 2946 N N . PHE A 1 430 ? 178.655 96.562 9.423 1.00 31.44 ? 428 PHE A N 1 ATOM 2947 C CA . PHE A 1 430 ? 177.823 97.628 9.960 1.00 31.58 ? 428 PHE A CA 1 ATOM 2948 C C . PHE A 1 430 ? 178.627 98.552 10.839 1.00 39.73 ? 428 PHE A C 1 ATOM 2949 O O . PHE A 1 430 ? 179.688 98.165 11.331 1.00 40.25 ? 428 PHE A O 1 ATOM 2950 C CB . PHE A 1 430 ? 176.632 97.042 10.744 1.00 32.50 ? 428 PHE A CB 1 ATOM 2951 C CG . PHE A 1 430 ? 176.986 96.147 11.910 1.00 33.37 ? 428 PHE A CG 1 ATOM 2952 C CD1 . PHE A 1 430 ? 177.231 94.796 11.721 1.00 35.30 ? 428 PHE A CD1 1 ATOM 2953 C CD2 . PHE A 1 430 ? 177.026 96.647 13.202 1.00 35.57 ? 428 PHE A CD2 1 ATOM 2954 C CE1 . PHE A 1 430 ? 177.517 93.968 12.796 1.00 36.17 ? 428 PHE A CE1 1 ATOM 2955 C CE2 . PHE A 1 430 ? 177.332 95.818 14.278 1.00 38.56 ? 428 PHE A CE2 1 ATOM 2956 C CZ . PHE A 1 430 ? 177.572 94.482 14.067 1.00 36.06 ? 428 PHE A CZ 1 ATOM 2957 N N . ASP A 1 431 ? 178.112 99.755 11.070 1.00 38.50 ? 429 ASP A N 1 ATOM 2958 C CA . ASP A 1 431 ? 178.780 100.703 11.949 1.00 40.04 ? 429 ASP A CA 1 ATOM 2959 C C . ASP A 1 431 ? 178.673 100.230 13.382 1.00 44.32 ? 429 ASP A C 1 ATOM 2960 O O . ASP A 1 431 ? 177.581 99.846 13.806 1.00 44.82 ? 429 ASP A O 1 ATOM 2961 C CB . ASP A 1 431 ? 178.174 102.112 11.793 1.00 43.11 ? 429 ASP A CB 1 ATOM 2962 C CG . ASP A 1 431 ? 178.829 102.992 10.732 1.00 64.91 ? 429 ASP A CG 1 ATOM 2963 O OD1 . ASP A 1 431 ? 180.000 102.710 10.356 1.00 68.74 ? 429 ASP A OD1 1 ATOM 2964 O OD2 . ASP A 1 431 ? 178.210 104.014 10.341 1.00 72.20 ? 429 ASP A OD2 1 ATOM 2965 N N . ALA A 1 432 ? 179.805 100.233 14.120 1.00 41.06 ? 430 ALA A N 1 ATOM 2966 C CA . ALA A 1 432 ? 179.845 99.840 15.526 1.00 41.29 ? 430 ALA A CA 1 ATOM 2967 C C . ALA A 1 432 ? 178.802 100.651 16.320 1.00 48.00 ? 430 ALA A C 1 ATOM 2968 O O . ALA A 1 432 ? 178.807 101.886 16.222 1.00 48.54 ? 430 ALA A O 1 ATOM 2969 C CB . ALA A 1 432 ? 181.236 100.069 16.091 1.00 41.96 ? 430 ALA A CB 1 ATOM 2970 N N . PRO A 1 433 ? 177.820 100.007 17.007 1.00 45.64 ? 431 PRO A N 1 ATOM 2971 C CA . PRO A 1 433 ? 176.825 100.802 17.759 1.00 45.91 ? 431 PRO A CA 1 ATOM 2972 C C . PRO A 1 433 ? 177.421 101.387 19.043 1.00 52.30 ? 431 PRO A C 1 ATOM 2973 O O . PRO A 1 433 ? 178.256 100.750 19.694 1.00 53.93 ? 431 PRO A O 1 ATOM 2974 C CB . PRO A 1 433 ? 175.722 99.789 18.059 1.00 47.03 ? 431 PRO A CB 1 ATOM 2975 C CG . PRO A 1 433 ? 176.440 98.504 18.164 1.00 51.16 ? 431 PRO A CG 1 ATOM 2976 C CD . PRO A 1 433 ? 177.619 98.559 17.223 1.00 46.75 ? 431 PRO A CD 1 ATOM 2977 N N . PHE A 1 434 ? 176.985 102.591 19.421 1.00 47.81 ? 432 PHE A N 1 ATOM 2978 C CA . PHE A 1 434 ? 177.429 103.290 20.643 1.00 46.82 ? 432 PHE A CA 1 ATOM 2979 C C . PHE A 1 434 ? 178.879 103.731 20.574 1.00 53.56 ? 432 PHE A C 1 ATOM 2980 O O . PHE A 1 434 ? 179.391 104.228 21.565 1.00 54.72 ? 432 PHE A O 1 ATOM 2981 C CB . PHE A 1 434 ? 177.130 102.518 21.946 1.00 47.71 ? 432 PHE A CB 1 ATOM 2982 C CG . PHE A 1 434 ? 175.775 101.854 21.948 1.00 48.97 ? 432 PHE A CG 1 ATOM 2983 C CD1 . PHE A 1 434 ? 174.617 102.601 22.106 1.00 51.64 ? 432 PHE A CD1 1 ATOM 2984 C CD2 . PHE A 1 434 ? 175.652 100.488 21.718 1.00 50.41 ? 432 PHE A CD2 1 ATOM 2985 C CE1 . PHE A 1 434 ? 173.364 101.996 22.026 1.00 52.41 ? 432 PHE A CE1 1 ATOM 2986 C CE2 . PHE A 1 434 ? 174.396 99.883 21.656 1.00 52.74 ? 432 PHE A CE2 1 ATOM 2987 C CZ . PHE A 1 434 ? 173.262 100.638 21.814 1.00 50.82 ? 432 PHE A CZ 1 ATOM 2988 N N . ARG A 1 435 ? 179.501 103.681 19.383 1.00 51.30 ? 433 ARG A N 1 ATOM 2989 C CA . ARG A 1 435 ? 180.841 104.222 19.173 1.00 51.71 ? 433 ARG A CA 1 ATOM 2990 C C . ARG A 1 435 ? 180.742 105.786 19.283 1.00 62.67 ? 433 ARG A C 1 ATOM 2991 O O . ARG A 1 435 ? 179.685 106.352 18.945 1.00 61.70 ? 433 ARG A O 1 ATOM 2992 C CB . ARG A 1 435 ? 181.388 103.806 17.785 1.00 45.51 ? 433 ARG A CB 1 ATOM 2993 C CG . ARG A 1 435 ? 180.780 104.567 16.615 1.00 44.77 ? 433 ARG A CG 1 ATOM 2994 C CD . ARG A 1 435 ? 181.221 104.081 15.246 1.00 56.29 ? 433 ARG A CD 1 ATOM 2995 N NE . ARG A 1 435 ? 180.669 104.948 14.198 1.00 70.85 ? 433 ARG A NE 1 ATOM 2996 C CZ . ARG A 1 435 ? 180.848 104.784 12.889 1.00 90.82 ? 433 ARG A CZ 1 ATOM 2997 N NH1 . ARG A 1 435 ? 180.313 105.640 12.030 1.00 84.30 ? 433 ARG A NH1 1 ATOM 2998 N NH2 . ARG A 1 435 ? 181.556 103.756 12.429 1.00 73.68 ? 433 ARG A NH2 1 ATOM 2999 N N . PRO A 1 436 ? 181.805 106.503 19.751 1.00 64.07 ? 434 PRO A N 1 ATOM 3000 C CA . PRO A 1 436 ? 181.715 107.985 19.809 1.00 64.44 ? 434 PRO A CA 1 ATOM 3001 C C . PRO A 1 436 ? 181.642 108.611 18.408 1.00 66.73 ? 434 PRO A C 1 ATOM 3002 O O . PRO A 1 436 ? 182.262 108.093 17.485 1.00 65.25 ? 434 PRO A O 1 ATOM 3003 C CB . PRO A 1 436 ? 182.991 108.404 20.560 1.00 66.55 ? 434 PRO A CB 1 ATOM 3004 C CG . PRO A 1 436 ? 183.582 107.123 21.131 1.00 71.21 ? 434 PRO A CG 1 ATOM 3005 C CD . PRO A 1 436 ? 183.120 106.019 20.229 1.00 66.44 ? 434 PRO A CD 1 ATOM 3006 N N . ALA A 1 437 ? 180.883 109.715 18.255 1.00 63.69 ? 435 ALA A N 1 ATOM 3007 C CA . ALA A 1 437 ? 180.641 110.431 16.987 1.00 63.92 ? 435 ALA A CA 1 ATOM 3008 C C . ALA A 1 437 ? 181.913 110.812 16.169 1.00 68.45 ? 435 ALA A C 1 ATOM 3009 O O . ALA A 1 437 ? 181.820 111.016 14.951 1.00 67.38 ? 435 ALA A O 1 ATOM 3010 C CB . ALA A 1 437 ? 179.786 111.665 17.246 1.00 64.67 ? 435 ALA A CB 1 ATOM 3011 N N . ASP A 1 438 ? 183.089 110.878 16.846 1.00 65.78 ? 436 ASP A N 1 ATOM 3012 C CA . ASP A 1 438 ? 184.410 111.182 16.277 1.00 65.18 ? 436 ASP A CA 1 ATOM 3013 C C . ASP A 1 438 ? 185.212 109.906 15.942 1.00 70.49 ? 436 ASP A C 1 ATOM 3014 O O . ASP A 1 438 ? 186.416 109.995 15.670 1.00 69.80 ? 436 ASP A O 1 ATOM 3015 C CB . ASP A 1 438 ? 185.209 112.084 17.237 1.00 66.11 ? 436 ASP A CB 1 ATOM 3016 C CG . ASP A 1 438 ? 185.461 111.481 18.608 1.00 67.08 ? 436 ASP A CG 1 ATOM 3017 O OD1 . ASP A 1 438 ? 184.513 111.455 19.427 1.00 65.84 ? 436 ASP A OD1 1 ATOM 3018 O OD2 . ASP A 1 438 ? 186.622 111.085 18.879 1.00 68.30 ? 436 ASP A OD2 1 ATOM 3019 N N . THR A 1 439 ? 184.549 108.719 15.998 1.00 68.45 ? 437 THR A N 1 ATOM 3020 C CA . THR A 1 439 ? 185.139 107.401 15.700 1.00 68.79 ? 437 THR A CA 1 ATOM 3021 C C . THR A 1 439 ? 184.359 106.715 14.548 1.00 73.72 ? 437 THR A C 1 ATOM 3022 O O . THR A 1 439 ? 183.133 106.863 14.441 1.00 71.48 ? 437 THR A O 1 ATOM 3023 C CB . THR A 1 439 ? 185.315 106.522 16.968 1.00 76.69 ? 437 THR A CB 1 ATOM 3024 O OG1 . THR A 1 439 ? 184.056 105.999 17.384 1.00 77.57 ? 437 THR A OG1 1 ATOM 3025 C CG2 . THR A 1 439 ? 186.015 107.249 18.131 1.00 72.97 ? 437 THR A CG2 1 ATOM 3026 N N . HIS A 1 440 ? 185.098 106.016 13.663 1.00 73.25 ? 438 HIS A N 1 ATOM 3027 C CA . HIS A 1 440 ? 184.565 105.369 12.461 1.00 74.59 ? 438 HIS A CA 1 ATOM 3028 C C . HIS A 1 440 ? 184.859 103.850 12.368 1.00 72.71 ? 438 HIS A C 1 ATOM 3029 O O . HIS A 1 440 ? 185.387 103.355 11.359 1.00 72.12 ? 438 HIS A O 1 ATOM 3030 C CB . HIS A 1 440 ? 185.054 106.114 11.203 1.00 77.61 ? 438 HIS A CB 1 ATOM 3031 C CG . HIS A 1 440 ? 184.435 105.636 9.924 1.00 82.70 ? 438 HIS A CG 1 ATOM 3032 N ND1 . HIS A 1 440 ? 184.898 104.497 9.268 1.00 85.24 ? 438 HIS A ND1 1 ATOM 3033 C CD2 . HIS A 1 440 ? 183.434 106.185 9.195 1.00 85.38 ? 438 HIS A CD2 1 ATOM 3034 C CE1 . HIS A 1 440 ? 184.148 104.382 8.183 1.00 85.17 ? 438 HIS A CE1 1 ATOM 3035 N NE2 . HIS A 1 440 ? 183.252 105.375 8.095 1.00 85.48 ? 438 HIS A NE2 1 ATOM 3036 N N . ASN A 1 441 ? 184.464 103.119 13.416 1.00 63.78 ? 439 ASN A N 1 ATOM 3037 C CA . ASN A 1 441 ? 184.657 101.681 13.508 1.00 60.85 ? 439 ASN A CA 1 ATOM 3038 C C . ASN A 1 441 ? 183.537 100.875 12.843 1.00 58.46 ? 439 ASN A C 1 ATOM 3039 O O . ASN A 1 441 ? 182.354 101.110 13.114 1.00 58.89 ? 439 ASN A O 1 ATOM 3040 C CB . ASN A 1 441 ? 184.754 101.263 14.974 1.00 61.15 ? 439 ASN A CB 1 ATOM 3041 C CG . ASN A 1 441 ? 185.662 102.120 15.814 1.00 85.83 ? 439 ASN A CG 1 ATOM 3042 O OD1 . ASN A 1 441 ? 186.868 102.241 15.551 1.00 76.39 ? 439 ASN A OD1 1 ATOM 3043 N ND2 . ASN A 1 441 ? 185.099 102.699 16.871 1.00 78.80 ? 439 ASN A ND2 1 ATOM 3044 N N . GLU A 1 442 ? 183.902 99.891 12.013 1.00 48.51 ? 440 GLU A N 1 ATOM 3045 C CA . GLU A 1 442 ? 182.885 99.005 11.492 1.00 46.08 ? 440 GLU A CA 1 ATOM 3046 C C . GLU A 1 442 ? 183.142 97.548 11.911 1.00 45.68 ? 440 GLU A C 1 ATOM 3047 O O . GLU A 1 442 ? 184.286 97.116 12.094 1.00 45.33 ? 440 GLU A O 1 ATOM 3048 C CB . GLU A 1 442 ? 182.626 99.163 9.994 1.00 47.45 ? 440 GLU A CB 1 ATOM 3049 C CG . GLU A 1 442 ? 183.720 98.706 9.054 1.00 58.47 ? 440 GLU A CG 1 ATOM 3050 C CD . GLU A 1 442 ? 183.379 98.948 7.597 1.00 87.40 ? 440 GLU A CD 1 ATOM 3051 O OE1 . GLU A 1 442 ? 182.292 99.507 7.312 1.00 75.54 ? 440 GLU A OE1 1 ATOM 3052 O OE2 . GLU A 1 442 ? 184.204 98.571 6.735 1.00 93.42 ? 440 GLU A OE2 1 ATOM 3053 N N . VAL A 1 443 ? 182.058 96.815 12.128 1.00 38.15 ? 441 VAL A N 1 ATOM 3054 C CA . VAL A 1 443 ? 182.148 95.418 12.503 1.00 35.70 ? 441 VAL A CA 1 ATOM 3055 C C . VAL A 1 443 ? 182.060 94.570 11.245 1.00 34.75 ? 441 VAL A C 1 ATOM 3056 O O . VAL A 1 443 ? 181.119 94.713 10.470 1.00 34.72 ? 441 VAL A O 1 ATOM 3057 C CB . VAL A 1 443 ? 181.070 95.044 13.541 1.00 39.34 ? 441 VAL A CB 1 ATOM 3058 C CG1 . VAL A 1 443 ? 181.207 93.583 13.986 1.00 38.89 ? 441 VAL A CG1 1 ATOM 3059 C CG2 . VAL A 1 443 ? 181.113 95.998 14.737 1.00 39.09 ? 441 VAL A CG2 1 ATOM 3060 N N . ARG A 1 444 ? 183.046 93.708 11.041 1.00 28.86 ? 442 ARG A N 1 ATOM 3061 C CA . ARG A 1 444 ? 183.130 92.744 9.940 1.00 28.10 ? 442 ARG A CA 1 ATOM 3062 C C . ARG A 1 444 ? 184.146 91.701 10.315 1.00 29.55 ? 442 ARG A C 1 ATOM 3063 O O . ARG A 1 444 ? 184.928 91.927 11.229 1.00 31.07 ? 442 ARG A O 1 ATOM 3064 C CB . ARG A 1 444 ? 183.522 93.418 8.596 1.00 32.16 ? 442 ARG A CB 1 ATOM 3065 C CG . ARG A 1 444 ? 184.810 94.252 8.643 1.00 45.20 ? 442 ARG A CG 1 ATOM 3066 C CD . ARG A 1 444 ? 185.116 94.889 7.307 1.00 55.39 ? 442 ARG A CD 1 ATOM 3067 N NE . ARG A 1 444 ? 186.260 95.791 7.413 1.00 71.18 ? 442 ARG A NE 1 ATOM 3068 N N . PHE A 1 445 ? 184.171 90.581 9.600 1.00 22.88 ? 443 PHE A N 1 ATOM 3069 C CA . PHE A 1 445 ? 185.140 89.518 9.818 1.00 20.86 ? 443 PHE A CA 1 ATOM 3070 C C . PHE A 1 445 ? 185.827 89.201 8.495 1.00 28.53 ? 443 PHE A C 1 ATOM 3071 O O . PHE A 1 445 ? 185.225 89.398 7.447 1.00 29.93 ? 443 PHE A O 1 ATOM 3072 C CB . PHE A 1 445 ? 184.426 88.246 10.305 1.00 20.77 ? 443 PHE A CB 1 ATOM 3073 C CG . PHE A 1 445 ? 183.440 88.409 11.426 1.00 19.28 ? 443 PHE A CG 1 ATOM 3074 C CD1 . PHE A 1 445 ? 183.867 88.444 12.748 1.00 21.17 ? 443 PHE A CD1 1 ATOM 3075 C CD2 . PHE A 1 445 ? 182.084 88.502 11.167 1.00 19.49 ? 443 PHE A CD2 1 ATOM 3076 C CE1 . PHE A 1 445 ? 182.959 88.616 13.790 1.00 21.47 ? 443 PHE A CE1 1 ATOM 3077 C CE2 . PHE A 1 445 ? 181.163 88.657 12.217 1.00 22.29 ? 443 PHE A CE2 1 ATOM 3078 C CZ . PHE A 1 445 ? 181.606 88.720 13.519 1.00 20.36 ? 443 PHE A CZ 1 ATOM 3079 N N . ASP A 1 446 ? 187.056 88.664 8.520 1.00 26.04 ? 444 ASP A N 1 ATOM 3080 C CA . ASP A 1 446 ? 187.709 88.250 7.289 1.00 25.79 ? 444 ASP A CA 1 ATOM 3081 C C . ASP A 1 446 ? 187.092 86.870 6.892 1.00 34.43 ? 444 ASP A C 1 ATOM 3082 O O . ASP A 1 446 ? 186.097 86.443 7.511 1.00 33.73 ? 444 ASP A O 1 ATOM 3083 C CB . ASP A 1 446 ? 189.244 88.195 7.472 1.00 27.01 ? 444 ASP A CB 1 ATOM 3084 C CG . ASP A 1 446 ? 189.812 87.183 8.460 1.00 40.29 ? 444 ASP A CG 1 ATOM 3085 O OD1 . ASP A 1 446 ? 189.070 86.261 8.874 1.00 41.57 ? 444 ASP A OD1 1 ATOM 3086 O OD2 . ASP A 1 446 ? 191.012 87.293 8.798 1.00 48.04 ? 444 ASP A OD2 1 ATOM 3087 N N . ARG A 1 447 ? 187.690 86.173 5.884 1.00 32.61 ? 445 ARG A N 1 ATOM 3088 C CA . ARG A 1 447 ? 187.254 84.852 5.396 1.00 32.25 ? 445 ARG A CA 1 ATOM 3089 C C . ARG A 1 447 ? 187.247 83.813 6.528 1.00 34.22 ? 445 ARG A C 1 ATOM 3090 O O . ARG A 1 447 ? 186.490 82.840 6.459 1.00 33.63 ? 445 ARG A O 1 ATOM 3091 C CB . ARG A 1 447 ? 188.233 84.330 4.313 1.00 33.36 ? 445 ARG A CB 1 ATOM 3092 C CG . ARG A 1 447 ? 188.153 84.998 2.961 1.00 50.08 ? 445 ARG A CG 1 ATOM 3093 C CD . ARG A 1 447 ? 189.082 84.295 1.974 1.00 65.05 ? 445 ARG A CD 1 ATOM 3094 N NE . ARG A 1 447 ? 189.343 85.092 0.770 1.00 75.09 ? 445 ARG A NE 1 ATOM 3095 C CZ . ARG A 1 447 ? 190.242 86.074 0.695 1.00 94.02 ? 445 ARG A CZ 1 ATOM 3096 N NH1 . ARG A 1 447 ? 190.973 86.402 1.760 1.00 77.01 ? 445 ARG A NH1 1 ATOM 3097 N NH2 . ARG A 1 447 ? 190.406 86.747 -0.439 1.00 80.99 ? 445 ARG A NH2 1 ATOM 3098 N N . PHE A 1 448 ? 188.145 83.990 7.522 1.00 29.11 ? 446 PHE A N 1 ATOM 3099 C CA . PHE A 1 448 ? 188.357 83.034 8.606 1.00 28.93 ? 446 PHE A CA 1 ATOM 3100 C C . PHE A 1 448 ? 187.643 83.419 9.887 1.00 30.73 ? 446 PHE A C 1 ATOM 3101 O O . PHE A 1 448 ? 187.739 82.721 10.880 1.00 30.31 ? 446 PHE A O 1 ATOM 3102 C CB . PHE A 1 448 ? 189.861 82.770 8.809 1.00 30.78 ? 446 PHE A CB 1 ATOM 3103 C CG . PHE A 1 448 ? 190.544 82.565 7.473 1.00 32.58 ? 446 PHE A CG 1 ATOM 3104 C CD1 . PHE A 1 448 ? 190.356 81.393 6.754 1.00 34.56 ? 446 PHE A CD1 1 ATOM 3105 C CD2 . PHE A 1 448 ? 191.260 83.600 6.874 1.00 36.81 ? 446 PHE A CD2 1 ATOM 3106 C CE1 . PHE A 1 448 ? 190.934 81.223 5.495 1.00 36.25 ? 446 PHE A CE1 1 ATOM 3107 C CE2 . PHE A 1 448 ? 191.807 83.449 5.598 1.00 40.21 ? 446 PHE A CE2 1 ATOM 3108 C CZ . PHE A 1 448 ? 191.667 82.248 4.928 1.00 38.12 ? 446 PHE A CZ 1 ATOM 3109 N N . GLY A 1 449 ? 186.835 84.452 9.804 1.00 27.16 ? 447 GLY A N 1 ATOM 3110 C CA . GLY A 1 449 ? 186.004 84.918 10.905 1.00 26.58 ? 447 GLY A CA 1 ATOM 3111 C C . GLY A 1 449 ? 186.677 85.772 11.949 1.00 28.22 ? 447 GLY A C 1 ATOM 3112 O O . GLY A 1 449 ? 186.124 85.906 13.029 1.00 27.50 ? 447 GLY A O 1 ATOM 3113 N N . ASP A 1 450 ? 187.846 86.371 11.648 1.00 24.91 ? 448 ASP A N 1 ATOM 3114 C CA . ASP A 1 450 ? 188.593 87.169 12.624 1.00 24.32 ? 448 ASP A CA 1 ATOM 3115 C C . ASP A 1 450 ? 188.405 88.658 12.461 1.00 29.78 ? 448 ASP A C 1 ATOM 3116 O O . ASP A 1 450 ? 188.087 89.110 11.369 1.00 30.01 ? 448 ASP A O 1 ATOM 3117 C CB . ASP A 1 450 ? 190.091 86.804 12.593 1.00 25.77 ? 448 ASP A CB 1 ATOM 3118 C CG . ASP A 1 450 ? 190.411 85.325 12.750 1.00 36.42 ? 448 ASP A CG 1 ATOM 3119 O OD1 . ASP A 1 450 ? 189.844 84.691 13.646 1.00 39.62 ? 448 ASP A OD1 1 ATOM 3120 O OD2 . ASP A 1 450 ? 191.231 84.809 11.971 1.00 41.44 ? 448 ASP A OD2 1 ATOM 3121 N N . GLY A 1 451 ? 188.637 89.403 13.545 1.00 28.22 ? 449 GLY A N 1 ATOM 3122 C CA . GLY A 1 451 ? 188.587 90.868 13.590 1.00 28.37 ? 449 GLY A CA 1 ATOM 3123 C C . GLY A 1 451 ? 189.906 91.514 13.214 1.00 35.07 ? 449 GLY A C 1 ATOM 3124 O O . GLY A 1 451 ? 190.924 90.832 13.073 1.00 31.54 ? 449 GLY A O 1 ATOM 3125 N N . ILE A 1 452 ? 189.906 92.820 13.149 1.00 39.44 ? 450 ILE A N 1 ATOM 3126 C CA . ILE A 1 452 ? 191.074 93.558 12.715 1.00 42.46 ? 450 ILE A CA 1 ATOM 3127 C C . ILE A 1 452 ? 192.055 93.998 13.776 1.00 50.57 ? 450 ILE A C 1 ATOM 3128 O O . ILE A 1 452 ? 191.688 94.647 14.734 1.00 50.28 ? 450 ILE A O 1 ATOM 3129 C CB . ILE A 1 452 ? 190.665 94.757 11.901 1.00 46.39 ? 450 ILE A CB 1 ATOM 3130 C CG1 . ILE A 1 452 ? 189.682 94.307 10.849 1.00 47.71 ? 450 ILE A CG1 1 ATOM 3131 C CG2 . ILE A 1 452 ? 191.870 95.344 11.224 1.00 47.07 ? 450 ILE A CG2 1 ATOM 3132 C CD1 . ILE A 1 452 ? 188.286 94.114 11.374 1.00 61.52 ? 450 ILE A CD1 1 ATOM 3133 N N . GLY A 1 453 ? 193.314 93.628 13.544 1.00 47.84 ? 451 GLY A N 1 ATOM 3134 C CA . GLY A 1 453 ? 194.442 93.837 14.453 1.00 47.97 ? 451 GLY A CA 1 ATOM 3135 C C . GLY A 1 453 ? 194.826 95.253 14.855 1.00 52.10 ? 451 GLY A C 1 ATOM 3136 O O . GLY A 1 453 ? 195.832 95.765 14.341 1.00 53.69 ? 451 GLY A O 1 ATOM 3137 N N . ARG A 1 454 ? 194.074 95.878 15.827 1.00 44.81 ? 452 ARG A N 1 ATOM 3138 C CA . ARG A 1 454 ? 194.364 97.219 16.386 1.00 43.32 ? 452 ARG A CA 1 ATOM 3139 C C . ARG A 1 454 ? 194.576 97.204 17.942 1.00 42.09 ? 452 ARG A C 1 ATOM 3140 O O . ARG A 1 454 ? 193.664 96.844 18.687 1.00 42.31 ? 452 ARG A O 1 ATOM 3141 C CB . ARG A 1 454 ? 193.299 98.238 15.961 1.00 45.12 ? 452 ARG A CB 1 ATOM 3142 N N . TYR A 1 455 ? 195.776 97.581 18.419 1.00 33.05 ? 453 TYR A N 1 ATOM 3143 C CA . TYR A 1 455 ? 196.116 97.526 19.845 1.00 30.14 ? 453 TYR A CA 1 ATOM 3144 C C . TYR A 1 455 ? 196.556 98.841 20.420 1.00 33.57 ? 453 TYR A C 1 ATOM 3145 O O . TYR A 1 455 ? 197.135 99.662 19.716 1.00 33.25 ? 453 TYR A O 1 ATOM 3146 C CB . TYR A 1 455 ? 197.278 96.537 20.073 1.00 29.43 ? 453 TYR A CB 1 ATOM 3147 C CG . TYR A 1 455 ? 197.019 95.152 19.527 1.00 30.22 ? 453 TYR A CG 1 ATOM 3148 C CD1 . TYR A 1 455 ? 196.377 94.188 20.295 1.00 30.78 ? 453 TYR A CD1 1 ATOM 3149 C CD2 . TYR A 1 455 ? 197.400 94.809 18.230 1.00 30.54 ? 453 TYR A CD2 1 ATOM 3150 C CE1 . TYR A 1 455 ? 196.128 92.918 19.790 1.00 30.86 ? 453 TYR A CE1 1 ATOM 3151 C CE2 . TYR A 1 455 ? 197.124 93.554 17.705 1.00 30.56 ? 453 TYR A CE2 1 ATOM 3152 C CZ . TYR A 1 455 ? 196.485 92.610 18.487 1.00 34.23 ? 453 TYR A CZ 1 ATOM 3153 O OH . TYR A 1 455 ? 196.212 91.365 17.971 1.00 30.63 ? 453 TYR A OH 1 ATOM 3154 N N . ASN A 1 456 ? 196.376 98.992 21.732 1.00 29.56 ? 454 ASN A N 1 ATOM 3155 C CA . ASN A 1 456 ? 196.910 100.103 22.507 1.00 28.83 ? 454 ASN A CA 1 ATOM 3156 C C . ASN A 1 456 ? 198.088 99.604 23.339 1.00 30.66 ? 454 ASN A C 1 ATOM 3157 O O . ASN A 1 456 ? 198.152 98.416 23.702 1.00 30.70 ? 454 ASN A O 1 ATOM 3158 C CB . ASN A 1 456 ? 195.853 100.721 23.380 1.00 30.00 ? 454 ASN A CB 1 ATOM 3159 C CG . ASN A 1 456 ? 194.928 101.568 22.583 1.00 39.20 ? 454 ASN A CG 1 ATOM 3160 O OD1 . ASN A 1 456 ? 195.319 102.140 21.566 1.00 31.35 ? 454 ASN A OD1 1 ATOM 3161 N ND2 . ASN A 1 456 ? 193.675 101.620 22.999 1.00 31.08 ? 454 ASN A ND2 1 ATOM 3162 N N . ILE A 1 457 ? 199.009 100.481 23.618 1.00 24.99 ? 455 ILE A N 1 ATOM 3163 C CA . ILE A 1 457 ? 200.155 100.096 24.381 1.00 24.39 ? 455 ILE A CA 1 ATOM 3164 C C . ILE A 1 457 ? 200.327 100.951 25.604 1.00 29.60 ? 455 ILE A C 1 ATOM 3165 O O . ILE A 1 457 ? 200.283 102.132 25.564 1.00 30.09 ? 455 ILE A O 1 ATOM 3166 C CB . ILE A 1 457 ? 201.401 100.088 23.518 1.00 25.47 ? 455 ILE A CB 1 ATOM 3167 C CG1 . ILE A 1 457 ? 201.216 99.099 22.395 1.00 23.49 ? 455 ILE A CG1 1 ATOM 3168 C CG2 . ILE A 1 457 ? 202.591 99.731 24.346 1.00 24.66 ? 455 ILE A CG2 1 ATOM 3169 C CD1 . ILE A 1 457 ? 202.085 99.357 21.225 1.00 19.65 ? 455 ILE A CD1 1 ATOM 3170 N N . PHE A 1 458 ? 200.492 100.296 26.715 1.00 25.94 ? 456 PHE A N 1 ATOM 3171 C CA . PHE A 1 458 ? 200.522 100.967 27.994 1.00 25.89 ? 456 PHE A CA 1 ATOM 3172 C C . PHE A 1 458 ? 201.800 100.763 28.758 1.00 32.87 ? 456 PHE A C 1 ATOM 3173 O O . PHE A 1 458 ? 202.605 99.894 28.432 1.00 33.12 ? 456 PHE A O 1 ATOM 3174 C CB . PHE A 1 458 ? 199.339 100.503 28.849 1.00 26.39 ? 456 PHE A CB 1 ATOM 3175 C CG . PHE A 1 458 ? 197.992 100.748 28.231 1.00 27.44 ? 456 PHE A CG 1 ATOM 3176 C CD1 . PHE A 1 458 ? 197.297 101.927 28.484 1.00 30.88 ? 456 PHE A CD1 1 ATOM 3177 C CD2 . PHE A 1 458 ? 197.381 99.776 27.443 1.00 27.82 ? 456 PHE A CD2 1 ATOM 3178 C CE1 . PHE A 1 458 ? 196.028 102.141 27.919 1.00 30.95 ? 456 PHE A CE1 1 ATOM 3179 C CE2 . PHE A 1 458 ? 196.107 99.977 26.908 1.00 29.37 ? 456 PHE A CE2 1 ATOM 3180 C CZ . PHE A 1 458 ? 195.452 101.161 27.130 1.00 28.42 ? 456 PHE A CZ 1 ATOM 3181 N N . THR A 1 459 ? 201.963 101.580 29.796 1.00 31.09 ? 457 THR A N 1 ATOM 3182 C CA . THR A 1 459 ? 203.022 101.511 30.779 1.00 32.01 ? 457 THR A CA 1 ATOM 3183 C C . THR A 1 459 ? 202.319 101.644 32.130 1.00 38.43 ? 457 THR A C 1 ATOM 3184 O O . THR A 1 459 ? 201.346 102.426 32.253 1.00 37.80 ? 457 THR A O 1 ATOM 3185 C CB . THR A 1 459 ? 204.130 102.576 30.529 1.00 43.83 ? 457 THR A CB 1 ATOM 3186 O OG1 . THR A 1 459 ? 205.368 102.174 31.144 1.00 40.08 ? 457 THR A OG1 1 ATOM 3187 C CG2 . THR A 1 459 ? 203.732 103.972 30.996 1.00 42.01 ? 457 THR A CG2 1 ATOM 3188 N N . TYR A 1 460 ? 202.771 100.828 33.116 1.00 34.51 ? 458 TYR A N 1 ATOM 3189 C CA . TYR A 1 460 ? 202.286 100.870 34.485 1.00 33.77 ? 458 TYR A CA 1 ATOM 3190 C C . TYR A 1 460 ? 203.281 101.734 35.261 1.00 39.08 ? 458 TYR A C 1 ATOM 3191 O O . TYR A 1 460 ? 204.435 101.341 35.425 1.00 37.86 ? 458 TYR A O 1 ATOM 3192 C CB . TYR A 1 460 ? 202.170 99.464 35.082 1.00 34.05 ? 458 TYR A CB 1 ATOM 3193 C CG . TYR A 1 460 ? 201.452 99.442 36.408 1.00 35.69 ? 458 TYR A CG 1 ATOM 3194 C CD1 . TYR A 1 460 ? 200.117 99.809 36.503 1.00 37.19 ? 458 TYR A CD1 1 ATOM 3195 C CD2 . TYR A 1 460 ? 202.107 99.049 37.573 1.00 37.12 ? 458 TYR A CD2 1 ATOM 3196 C CE1 . TYR A 1 460 ? 199.445 99.780 37.717 1.00 38.73 ? 458 TYR A CE1 1 ATOM 3197 C CE2 . TYR A 1 460 ? 201.444 99.020 38.801 1.00 38.01 ? 458 TYR A CE2 1 ATOM 3198 C CZ . TYR A 1 460 ? 200.110 99.385 38.864 1.00 44.81 ? 458 TYR A CZ 1 ATOM 3199 O OH . TYR A 1 460 ? 199.412 99.347 40.044 1.00 43.59 ? 458 TYR A OH 1 ATOM 3200 N N . LEU A 1 461 ? 202.859 102.942 35.657 1.00 38.35 ? 459 LEU A N 1 ATOM 3201 C CA . LEU A 1 461 ? 203.729 103.899 36.357 1.00 39.79 ? 459 LEU A CA 1 ATOM 3202 C C . LEU A 1 461 ? 203.121 104.486 37.609 1.00 47.41 ? 459 LEU A C 1 ATOM 3203 O O . LEU A 1 461 ? 201.897 104.478 37.746 1.00 47.31 ? 459 LEU A O 1 ATOM 3204 C CB . LEU A 1 461 ? 204.204 105.043 35.417 1.00 39.65 ? 459 LEU A CB 1 ATOM 3205 C CG . LEU A 1 461 ? 203.182 105.754 34.504 1.00 44.05 ? 459 LEU A CG 1 ATOM 3206 C CD1 . LEU A 1 461 ? 202.281 106.720 35.272 1.00 44.31 ? 459 LEU A CD1 1 ATOM 3207 C CD2 . LEU A 1 461 ? 203.892 106.537 33.441 1.00 46.25 ? 459 LEU A CD2 1 ATOM 3208 N N . ARG A 1 462 ? 203.974 105.032 38.509 1.00 46.70 ? 460 ARG A N 1 ATOM 3209 C CA . ARG A 1 462 ? 203.507 105.698 39.725 1.00 47.60 ? 460 ARG A CA 1 ATOM 3210 C C . ARG A 1 462 ? 203.498 107.164 39.429 1.00 52.61 ? 460 ARG A C 1 ATOM 3211 O O . ARG A 1 462 ? 204.556 107.742 39.164 1.00 52.86 ? 460 ARG A O 1 ATOM 3212 C CB . ARG A 1 462 ? 204.375 105.383 40.960 1.00 49.24 ? 460 ARG A CB 1 ATOM 3213 N N . ALA A 1 463 ? 202.284 107.743 39.387 1.00 49.96 ? 461 ALA A N 1 ATOM 3214 C CA . ALA A 1 463 ? 202.011 109.158 39.139 1.00 84.30 ? 461 ALA A CA 1 ATOM 3215 C C . ALA A 1 463 ? 202.238 109.972 40.417 1.00 122.02 ? 461 ALA A C 1 ATOM 3216 O O . ALA A 1 463 ? 202.699 111.111 40.359 1.00 88.14 ? 461 ALA A O 1 ATOM 3217 C CB . ALA A 1 463 ? 200.575 109.324 38.669 1.00 84.99 ? 461 ALA A CB 1 ATOM 3218 N N . GLY A 1 466 ? 200.078 110.299 44.194 1.00 64.44 ? 464 GLY A N 1 ATOM 3219 C CA . GLY A 1 466 ? 201.054 109.282 43.819 1.00 64.28 ? 464 GLY A CA 1 ATOM 3220 C C . GLY A 1 466 ? 200.445 107.900 43.655 1.00 67.06 ? 464 GLY A C 1 ATOM 3221 O O . GLY A 1 466 ? 200.905 106.919 44.263 1.00 66.56 ? 464 GLY A O 1 ATOM 3222 N N . ARG A 1 467 ? 199.373 107.826 42.849 1.00 61.18 ? 465 ARG A N 1 ATOM 3223 C CA . ARG A 1 467 ? 198.695 106.570 42.560 1.00 59.09 ? 465 ARG A CA 1 ATOM 3224 C C . ARG A 1 467 ? 199.438 105.860 41.410 1.00 57.60 ? 465 ARG A C 1 ATOM 3225 O O . ARG A 1 467 ? 200.117 106.505 40.610 1.00 54.85 ? 465 ARG A O 1 ATOM 3226 C CB . ARG A 1 467 ? 197.223 106.842 42.193 1.00 58.55 ? 465 ARG A CB 1 ATOM 3227 N N . TYR A 1 468 ? 199.334 104.528 41.353 1.00 52.24 ? 466 TYR A N 1 ATOM 3228 C CA . TYR A 1 468 ? 199.932 103.742 40.273 1.00 49.87 ? 466 TYR A CA 1 ATOM 3229 C C . TYR A 1 468 ? 198.864 103.625 39.224 1.00 50.43 ? 466 TYR A C 1 ATOM 3230 O O . TYR A 1 468 ? 197.725 103.260 39.543 1.00 51.48 ? 466 TYR A O 1 ATOM 3231 C CB . TYR A 1 468 ? 200.310 102.356 40.768 1.00 50.61 ? 466 TYR A CB 1 ATOM 3232 C CG . TYR A 1 468 ? 201.634 102.288 41.486 1.00 51.63 ? 466 TYR A CG 1 ATOM 3233 C CD1 . TYR A 1 468 ? 202.821 102.082 40.785 1.00 53.28 ? 466 TYR A CD1 1 ATOM 3234 C CD2 . TYR A 1 468 ? 201.700 102.382 42.872 1.00 51.91 ? 466 TYR A CD2 1 ATOM 3235 C CE1 . TYR A 1 468 ? 204.041 101.977 41.447 1.00 53.92 ? 466 TYR A CE1 1 ATOM 3236 C CE2 . TYR A 1 468 ? 202.919 102.299 43.544 1.00 53.06 ? 466 TYR A CE2 1 ATOM 3237 C CZ . TYR A 1 468 ? 204.086 102.082 42.829 1.00 61.27 ? 466 TYR A CZ 1 ATOM 3238 O OH . TYR A 1 468 ? 205.282 101.972 43.501 1.00 62.12 ? 466 TYR A OH 1 ATOM 3239 N N . ARG A 1 469 ? 199.195 103.965 37.985 1.00 43.25 ? 467 ARG A N 1 ATOM 3240 C CA . ARG A 1 469 ? 198.214 103.934 36.900 1.00 41.46 ? 467 ARG A CA 1 ATOM 3241 C C . ARG A 1 469 ? 198.764 103.347 35.584 1.00 40.99 ? 467 ARG A C 1 ATOM 3242 O O . ARG A 1 469 ? 199.984 103.190 35.413 1.00 39.20 ? 467 ARG A O 1 ATOM 3243 C CB . ARG A 1 469 ? 197.643 105.361 36.672 1.00 41.53 ? 467 ARG A CB 1 ATOM 3244 C CG . ARG A 1 469 ? 198.645 106.376 36.083 1.00 48.23 ? 467 ARG A CG 1 ATOM 3245 C CD . ARG A 1 469 ? 197.969 107.369 35.136 1.00 55.89 ? 467 ARG A CD 1 ATOM 3246 N NE . ARG A 1 469 ? 198.930 108.162 34.367 1.00 52.60 ? 467 ARG A NE 1 ATOM 3247 N N . TYR A 1 470 ? 197.844 103.069 34.645 1.00 34.93 ? 468 TYR A N 1 ATOM 3248 C CA . TYR A 1 470 ? 198.175 102.613 33.297 1.00 33.81 ? 468 TYR A CA 1 ATOM 3249 C C . TYR A 1 470 ? 198.137 103.844 32.377 1.00 42.19 ? 468 TYR A C 1 ATOM 3250 O O . TYR A 1 470 ? 197.159 104.614 32.396 1.00 43.26 ? 468 TYR A O 1 ATOM 3251 C CB . TYR A 1 470 ? 197.177 101.552 32.807 1.00 32.02 ? 468 TYR A CB 1 ATOM 3252 C CG . TYR A 1 470 ? 197.346 100.185 33.431 1.00 29.33 ? 468 TYR A CG 1 ATOM 3253 C CD1 . TYR A 1 470 ? 198.208 99.242 32.870 1.00 29.66 ? 468 TYR A CD1 1 ATOM 3254 C CD2 . TYR A 1 470 ? 196.604 99.810 34.548 1.00 29.28 ? 468 TYR A CD2 1 ATOM 3255 C CE1 . TYR A 1 470 ? 198.341 97.967 33.417 1.00 27.00 ? 468 TYR A CE1 1 ATOM 3256 C CE2 . TYR A 1 470 ? 196.695 98.517 35.078 1.00 29.83 ? 468 TYR A CE2 1 ATOM 3257 C CZ . TYR A 1 470 ? 197.555 97.597 34.497 1.00 31.68 ? 468 TYR A CZ 1 ATOM 3258 O OH . TYR A 1 470 ? 197.694 96.350 35.033 1.00 28.17 ? 468 TYR A OH 1 ATOM 3259 N N . GLN A 1 471 ? 199.210 104.039 31.586 1.00 38.36 ? 469 GLN A N 1 ATOM 3260 C CA . GLN A 1 471 ? 199.327 105.159 30.670 1.00 37.08 ? 469 GLN A CA 1 ATOM 3261 C C . GLN A 1 471 ? 199.543 104.690 29.235 1.00 39.89 ? 469 GLN A C 1 ATOM 3262 O O . GLN A 1 471 ? 200.542 104.026 28.955 1.00 39.53 ? 469 GLN A O 1 ATOM 3263 C CB . GLN A 1 471 ? 200.479 106.097 31.123 1.00 38.85 ? 469 GLN A CB 1 ATOM 3264 C CG . GLN A 1 471 ? 200.667 107.399 30.286 1.00 52.07 ? 469 GLN A CG 1 ATOM 3265 C CD . GLN A 1 471 ? 199.523 108.406 30.400 1.00 72.41 ? 469 GLN A CD 1 ATOM 3266 O OE1 . GLN A 1 471 ? 198.797 108.501 31.415 1.00 66.40 ? 469 GLN A OE1 1 ATOM 3267 N NE2 . GLN A 1 471 ? 199.342 109.189 29.349 1.00 65.00 ? 469 GLN A NE2 1 ATOM 3268 N N . LYS A 1 472 ? 198.632 105.091 28.317 1.00 35.94 ? 470 LYS A N 1 ATOM 3269 C CA . LYS A 1 472 ? 198.757 104.830 26.889 1.00 35.17 ? 470 LYS A CA 1 ATOM 3270 C C . LYS A 1 472 ? 199.974 105.599 26.400 1.00 44.06 ? 470 LYS A C 1 ATOM 3271 O O . LYS A 1 472 ? 200.055 106.822 26.579 1.00 46.31 ? 470 LYS A O 1 ATOM 3272 C CB . LYS A 1 472 ? 197.512 105.261 26.101 1.00 34.98 ? 470 LYS A CB 1 ATOM 3273 C CG . LYS A 1 472 ? 197.527 104.668 24.697 1.00 34.59 ? 470 LYS A CG 1 ATOM 3274 C CD . LYS A 1 472 ? 196.397 105.110 23.803 1.00 32.21 ? 470 LYS A CD 1 ATOM 3275 C CE . LYS A 1 472 ? 196.866 105.059 22.364 1.00 47.10 ? 470 LYS A CE 1 ATOM 3276 N NZ . LYS A 1 472 ? 195.744 105.208 21.389 1.00 66.21 ? 470 LYS A NZ 1 ATOM 3277 N N . VAL A 1 473 ? 200.943 104.865 25.847 1.00 39.85 ? 471 VAL A N 1 ATOM 3278 C CA . VAL A 1 473 ? 202.207 105.391 25.332 1.00 38.43 ? 471 VAL A CA 1 ATOM 3279 C C . VAL A 1 473 ? 202.359 105.095 23.819 1.00 41.01 ? 471 VAL A C 1 ATOM 3280 O O . VAL A 1 473 ? 203.420 105.348 23.249 1.00 41.12 ? 471 VAL A O 1 ATOM 3281 C CB . VAL A 1 473 ? 203.429 104.860 26.155 1.00 41.75 ? 471 VAL A CB 1 ATOM 3282 C CG1 . VAL A 1 473 ? 203.280 105.168 27.632 1.00 41.23 ? 471 VAL A CG1 1 ATOM 3283 C CG2 . VAL A 1 473 ? 203.669 103.362 25.935 1.00 41.36 ? 471 VAL A CG2 1 ATOM 3284 N N . GLY A 1 474 ? 201.335 104.518 23.205 1.00 35.54 ? 472 GLY A N 1 ATOM 3285 C CA . GLY A 1 474 ? 201.398 104.166 21.795 1.00 34.80 ? 472 GLY A CA 1 ATOM 3286 C C . GLY A 1 474 ? 200.348 103.176 21.343 1.00 37.66 ? 472 GLY A C 1 ATOM 3287 O O . GLY A 1 474 ? 199.442 102.821 22.098 1.00 36.85 ? 472 GLY A O 1 ATOM 3288 N N . TYR A 1 475 ? 200.462 102.745 20.091 1.00 34.14 ? 473 TYR A N 1 ATOM 3289 C CA . TYR A 1 475 ? 199.523 101.821 19.477 1.00 34.91 ? 473 TYR A CA 1 ATOM 3290 C C . TYR A 1 475 ? 200.173 100.969 18.410 1.00 37.74 ? 473 TYR A C 1 ATOM 3291 O O . TYR A 1 475 ? 201.236 101.314 17.895 1.00 37.60 ? 473 TYR A O 1 ATOM 3292 C CB . TYR A 1 475 ? 198.310 102.569 18.879 1.00 37.47 ? 473 TYR A CB 1 ATOM 3293 C CG . TYR A 1 475 ? 198.681 103.641 17.877 1.00 41.68 ? 473 TYR A CG 1 ATOM 3294 C CD1 . TYR A 1 475 ? 198.925 104.952 18.287 1.00 44.04 ? 473 TYR A CD1 1 ATOM 3295 C CD2 . TYR A 1 475 ? 198.777 103.352 16.518 1.00 43.45 ? 473 TYR A CD2 1 ATOM 3296 C CE1 . TYR A 1 475 ? 199.295 105.936 17.378 1.00 45.79 ? 473 TYR A CE1 1 ATOM 3297 C CE2 . TYR A 1 475 ? 199.115 104.338 15.591 1.00 45.20 ? 473 TYR A CE2 1 ATOM 3298 C CZ . TYR A 1 475 ? 199.361 105.635 16.026 1.00 55.61 ? 473 TYR A CZ 1 ATOM 3299 O OH . TYR A 1 475 ? 199.734 106.616 15.135 1.00 57.78 ? 473 TYR A OH 1 ATOM 3300 N N . TRP A 1 476 ? 199.510 99.873 18.048 1.00 33.34 ? 474 TRP A N 1 ATOM 3301 C CA . TRP A 1 476 ? 199.973 99.042 16.954 1.00 33.54 ? 474 TRP A CA 1 ATOM 3302 C C . TRP A 1 476 ? 198.813 98.840 15.981 1.00 37.88 ? 474 TRP A C 1 ATOM 3303 O O . TRP A 1 476 ? 197.719 98.405 16.374 1.00 37.27 ? 474 TRP A O 1 ATOM 3304 C CB . TRP A 1 476 ? 200.590 97.724 17.430 1.00 32.31 ? 474 TRP A CB 1 ATOM 3305 C CG . TRP A 1 476 ? 201.380 97.021 16.359 1.00 33.39 ? 474 TRP A CG 1 ATOM 3306 C CD1 . TRP A 1 476 ? 202.736 97.015 16.210 1.00 36.45 ? 474 TRP A CD1 1 ATOM 3307 C CD2 . TRP A 1 476 ? 200.857 96.178 15.315 1.00 32.95 ? 474 TRP A CD2 1 ATOM 3308 N NE1 . TRP A 1 476 ? 203.092 96.246 15.118 1.00 36.06 ? 474 TRP A NE1 1 ATOM 3309 C CE2 . TRP A 1 476 ? 201.957 95.726 14.550 1.00 37.02 ? 474 TRP A CE2 1 ATOM 3310 C CE3 . TRP A 1 476 ? 199.563 95.772 14.947 1.00 34.07 ? 474 TRP A CE3 1 ATOM 3311 C CZ2 . TRP A 1 476 ? 201.804 94.894 13.438 1.00 36.04 ? 474 TRP A CZ2 1 ATOM 3312 C CZ3 . TRP A 1 476 ? 199.412 94.948 13.839 1.00 35.92 ? 474 TRP A CZ3 1 ATOM 3313 C CH2 . TRP A 1 476 ? 200.523 94.519 13.099 1.00 36.43 ? 474 TRP A CH2 1 ATOM 3314 N N . ALA A 1 477 ? 199.049 99.222 14.721 1.00 33.56 ? 475 ALA A N 1 ATOM 3315 C CA . ALA A 1 477 ? 198.089 99.131 13.632 1.00 33.90 ? 475 ALA A CA 1 ATOM 3316 C C . ALA A 1 477 ? 198.872 98.956 12.323 1.00 40.03 ? 475 ALA A C 1 ATOM 3317 O O . ALA A 1 477 ? 199.218 99.949 11.655 1.00 39.72 ? 475 ALA A O 1 ATOM 3318 C CB . ALA A 1 477 ? 197.231 100.396 13.587 1.00 34.38 ? 475 ALA A CB 1 ATOM 3319 N N . GLU A 1 478 ? 199.190 97.690 11.985 1.00 38.32 ? 476 GLU A N 1 ATOM 3320 C CA . GLU A 1 478 ? 199.992 97.322 10.802 1.00 39.87 ? 476 GLU A CA 1 ATOM 3321 C C . GLU A 1 478 ? 201.294 98.153 10.845 1.00 44.59 ? 476 GLU A C 1 ATOM 3322 O O . GLU A 1 478 ? 201.633 98.862 9.897 1.00 46.01 ? 476 GLU A O 1 ATOM 3323 C CB . GLU A 1 478 ? 199.181 97.533 9.486 1.00 41.59 ? 476 GLU A CB 1 ATOM 3324 C CG . GLU A 1 478 ? 197.967 96.625 9.347 1.00 54.78 ? 476 GLU A CG 1 ATOM 3325 C CD . GLU A 1 478 ? 198.284 95.139 9.401 1.00 90.99 ? 476 GLU A CD 1 ATOM 3326 O OE1 . GLU A 1 478 ? 199.312 94.721 8.818 1.00 87.36 ? 476 GLU A OE1 1 ATOM 3327 O OE2 . GLU A 1 478 ? 197.508 94.394 10.043 1.00 91.87 ? 476 GLU A OE2 1 ATOM 3328 N N . GLY A 1 479 ? 201.927 98.139 12.012 1.00 38.99 ? 477 GLY A N 1 ATOM 3329 C CA . GLY A 1 479 ? 203.123 98.908 12.317 1.00 37.54 ? 477 GLY A CA 1 ATOM 3330 C C . GLY A 1 479 ? 203.044 99.550 13.693 1.00 38.70 ? 477 GLY A C 1 ATOM 3331 O O . GLY A 1 479 ? 201.971 99.982 14.127 1.00 36.79 ? 477 GLY A O 1 ATOM 3332 N N . LEU A 1 480 ? 204.200 99.621 14.380 1.00 34.97 ? 478 LEU A N 1 ATOM 3333 C CA . LEU A 1 480 ? 204.342 100.199 15.715 1.00 34.30 ? 478 LEU A CA 1 ATOM 3334 C C . LEU A 1 480 ? 204.509 101.719 15.723 1.00 43.33 ? 478 LEU A C 1 ATOM 3335 O O . LEU A 1 480 ? 205.320 102.264 14.973 1.00 44.39 ? 478 LEU A O 1 ATOM 3336 C CB . LEU A 1 480 ? 205.518 99.525 16.459 1.00 32.87 ? 478 LEU A CB 1 ATOM 3337 C CG . LEU A 1 480 ? 205.905 100.098 17.827 1.00 36.40 ? 478 LEU A CG 1 ATOM 3338 C CD1 . LEU A 1 480 ? 204.815 99.857 18.875 1.00 35.64 ? 478 LEU A CD1 1 ATOM 3339 C CD2 . LEU A 1 480 ? 207.246 99.566 18.294 1.00 38.93 ? 478 LEU A CD2 1 ATOM 3340 N N . THR A 1 481 ? 203.799 102.383 16.642 1.00 41.94 ? 479 THR A N 1 ATOM 3341 C CA . THR A 1 481 ? 203.884 103.813 16.901 1.00 42.86 ? 479 THR A CA 1 ATOM 3342 C C . THR A 1 481 ? 203.946 103.991 18.420 1.00 52.29 ? 479 THR A C 1 ATOM 3343 O O . THR A 1 481 ? 203.050 103.519 19.127 1.00 51.36 ? 479 THR A O 1 ATOM 3344 C CB . THR A 1 481 ? 202.647 104.523 16.356 1.00 50.31 ? 479 THR A CB 1 ATOM 3345 O OG1 . THR A 1 481 ? 202.347 104.072 15.025 1.00 54.55 ? 479 THR A OG1 1 ATOM 3346 C CG2 . THR A 1 481 ? 202.764 106.034 16.424 1.00 45.03 ? 479 THR A CG2 1 ATOM 3347 N N . LEU A 1 482 ? 204.989 104.660 18.931 1.00 54.08 ? 480 LEU A N 1 ATOM 3348 C CA . LEU A 1 482 ? 205.054 104.920 20.365 1.00 56.08 ? 480 LEU A CA 1 ATOM 3349 C C . LEU A 1 482 ? 205.799 106.218 20.691 1.00 64.29 ? 480 LEU A C 1 ATOM 3350 O O . LEU A 1 482 ? 206.769 106.547 20.018 1.00 65.44 ? 480 LEU A O 1 ATOM 3351 C CB . LEU A 1 482 ? 205.579 103.709 21.185 1.00 56.32 ? 480 LEU A CB 1 ATOM 3352 C CG . LEU A 1 482 ? 207.050 103.331 21.149 1.00 61.32 ? 480 LEU A CG 1 ATOM 3353 C CD1 . LEU A 1 482 ? 207.825 104.111 22.209 1.00 62.90 ? 480 LEU A CD1 1 ATOM 3354 C CD2 . LEU A 1 482 ? 207.225 101.859 21.474 1.00 60.32 ? 480 LEU A CD2 1 ATOM 3355 N N . ASP A 1 483 ? 205.329 106.953 21.715 1.00 63.22 ? 481 ASP A N 1 ATOM 3356 C CA . ASP A 1 483 ? 205.950 108.188 22.191 1.00 64.71 ? 481 ASP A CA 1 ATOM 3357 C C . ASP A 1 483 ? 206.802 107.903 23.424 1.00 70.17 ? 481 ASP A C 1 ATOM 3358 O O . ASP A 1 483 ? 206.261 107.678 24.516 1.00 69.18 ? 481 ASP A O 1 ATOM 3359 C CB . ASP A 1 483 ? 204.898 109.288 22.455 1.00 67.72 ? 481 ASP A CB 1 ATOM 3360 C CG . ASP A 1 483 ? 204.610 110.144 21.228 1.00 88.52 ? 481 ASP A CG 1 ATOM 3361 O OD1 . ASP A 1 483 ? 205.483 110.979 20.862 1.00 90.89 ? 481 ASP A OD1 1 ATOM 3362 O OD2 . ASP A 1 483 ? 203.528 109.956 20.606 1.00 95.29 ? 481 ASP A OD2 1 ATOM 3363 N N . THR A 1 484 ? 208.144 107.883 23.231 1.00 68.58 ? 482 THR A N 1 ATOM 3364 C CA . THR A 1 484 ? 209.153 107.598 24.266 1.00 68.74 ? 482 THR A CA 1 ATOM 3365 C C . THR A 1 484 ? 209.155 108.641 25.406 1.00 74.00 ? 482 THR A C 1 ATOM 3366 O O . THR A 1 484 ? 209.697 108.379 26.489 1.00 74.11 ? 482 THR A O 1 ATOM 3367 C CB . THR A 1 484 ? 210.529 107.420 23.623 1.00 74.26 ? 482 THR A CB 1 ATOM 3368 N N . SER A 1 485 ? 208.533 109.811 25.155 1.00 70.35 ? 483 SER A N 1 ATOM 3369 C CA . SER A 1 485 ? 208.361 110.918 26.098 1.00 69.89 ? 483 SER A CA 1 ATOM 3370 C C . SER A 1 485 ? 207.453 110.524 27.277 1.00 73.88 ? 483 SER A C 1 ATOM 3371 O O . SER A 1 485 ? 207.719 110.925 28.415 1.00 73.65 ? 483 SER A O 1 ATOM 3372 C CB . SER A 1 485 ? 207.756 112.112 25.376 1.00 73.66 ? 483 SER A CB 1 ATOM 3373 O OG . SER A 1 485 ? 206.582 111.731 24.675 1.00 83.75 ? 483 SER A OG 1 ATOM 3374 N N . LEU A 1 486 ? 206.391 109.732 26.998 1.00 70.09 ? 484 LEU A N 1 ATOM 3375 C CA . LEU A 1 486 ? 205.398 109.265 27.976 1.00 69.96 ? 484 LEU A CA 1 ATOM 3376 C C . LEU A 1 486 ? 205.899 108.198 28.972 1.00 73.51 ? 484 LEU A C 1 ATOM 3377 O O . LEU A 1 486 ? 205.307 108.048 30.052 1.00 72.06 ? 484 LEU A O 1 ATOM 3378 C CB . LEU A 1 486 ? 204.144 108.755 27.262 1.00 70.06 ? 484 LEU A CB 1 ATOM 3379 C CG . LEU A 1 486 ? 203.222 109.800 26.678 1.00 75.02 ? 484 LEU A CG 1 ATOM 3380 C CD1 . LEU A 1 486 ? 202.565 109.286 25.417 1.00 75.35 ? 484 LEU A CD1 1 ATOM 3381 C CD2 . LEU A 1 486 ? 202.174 110.221 27.682 1.00 77.42 ? 484 LEU A CD2 1 ATOM 3382 N N . ILE A 1 487 ? 206.953 107.437 28.593 1.00 70.68 ? 485 ILE A N 1 ATOM 3383 C CA . ILE A 1 487 ? 207.524 106.389 29.445 1.00 70.98 ? 485 ILE A CA 1 ATOM 3384 C C . ILE A 1 487 ? 208.646 106.997 30.332 1.00 75.61 ? 485 ILE A C 1 ATOM 3385 O O . ILE A 1 487 ? 209.537 107.671 29.800 1.00 75.73 ? 485 ILE A O 1 ATOM 3386 C CB . ILE A 1 487 ? 207.939 105.080 28.680 1.00 74.43 ? 485 ILE A CB 1 ATOM 3387 C CG1 . ILE A 1 487 ? 208.895 105.340 27.507 1.00 75.45 ? 485 ILE A CG1 1 ATOM 3388 C CG2 . ILE A 1 487 ? 206.725 104.276 28.209 1.00 74.30 ? 485 ILE A CG2 1 ATOM 3389 C CD1 . ILE A 1 487 ? 209.986 104.343 27.419 1.00 83.62 ? 485 ILE A CD1 1 ATOM 3390 N N . PRO A 1 488 ? 208.594 106.820 31.682 1.00 72.39 ? 486 PRO A N 1 ATOM 3391 C CA . PRO A 1 488 ? 209.599 107.464 32.556 1.00 72.20 ? 486 PRO A CA 1 ATOM 3392 C C . PRO A 1 488 ? 211.030 106.889 32.506 1.00 76.94 ? 486 PRO A C 1 ATOM 3393 O O . PRO A 1 488 ? 211.825 107.169 33.415 1.00 77.07 ? 486 PRO A O 1 ATOM 3394 C CB . PRO A 1 488 ? 208.986 107.345 33.966 1.00 73.69 ? 486 PRO A CB 1 ATOM 3395 C CG . PRO A 1 488 ? 207.593 106.838 33.775 1.00 77.99 ? 486 PRO A CG 1 ATOM 3396 C CD . PRO A 1 488 ? 207.589 106.092 32.486 1.00 73.74 ? 486 PRO A CD 1 ATOM 3397 N N . TRP A 1 489 ? 211.378 106.133 31.433 1.00 72.69 ? 487 TRP A N 1 ATOM 3398 C CA . TRP A 1 489 ? 212.716 105.572 31.197 1.00 80.39 ? 487 TRP A CA 1 ATOM 3399 C C . TRP A 1 489 ? 212.993 105.321 29.715 1.00 78.35 ? 487 TRP A C 1 ATOM 3400 O O . TRP A 1 489 ? 212.348 105.906 28.844 1.00 36.30 ? 487 TRP A O 1 ATOM 3401 C CB . TRP A 1 489 ? 212.988 104.317 32.047 1.00 79.19 ? 487 TRP A CB 1 ATOM 3402 C CG . TRP A 1 489 ? 211.856 103.332 32.082 1.00 80.31 ? 487 TRP A CG 1 ATOM 3403 C CD1 . TRP A 1 489 ? 210.976 103.129 33.105 1.00 83.14 ? 487 TRP A CD1 1 ATOM 3404 C CD2 . TRP A 1 489 ? 211.467 102.431 31.031 1.00 80.20 ? 487 TRP A CD2 1 ATOM 3405 N NE1 . TRP A 1 489 ? 210.064 102.156 32.759 1.00 82.55 ? 487 TRP A NE1 1 ATOM 3406 C CE2 . TRP A 1 489 ? 210.347 101.705 31.496 1.00 83.88 ? 487 TRP A CE2 1 ATOM 3407 C CE3 . TRP A 1 489 ? 211.952 102.175 29.733 1.00 81.20 ? 487 TRP A CE3 1 ATOM 3408 C CZ2 . TRP A 1 489 ? 209.706 100.746 30.712 1.00 82.98 ? 487 TRP A CZ2 1 ATOM 3409 C CZ3 . TRP A 1 489 ? 211.303 101.237 28.951 1.00 82.36 ? 487 TRP A CZ3 1 ATOM 3410 C CH2 . TRP A 1 489 ? 210.198 100.532 29.442 1.00 83.00 ? 487 TRP A CH2 1 ATOM 3411 N N . LYS B 1 25 ? 180.821 57.395 7.736 1.00 55.57 ? 23 LYS B N 1 ATOM 3412 C CA . LYS B 1 25 ? 179.395 57.028 7.774 1.00 55.55 ? 23 LYS B CA 1 ATOM 3413 C C . LYS B 1 25 ? 179.078 55.617 8.345 1.00 56.15 ? 23 LYS B C 1 ATOM 3414 O O . LYS B 1 25 ? 178.009 55.464 8.957 1.00 55.61 ? 23 LYS B O 1 ATOM 3415 C CB . LYS B 1 25 ? 178.718 57.187 6.389 1.00 58.12 ? 23 LYS B CB 1 ATOM 3416 N N . LYS B 1 26 ? 179.964 54.601 8.119 1.00 49.89 ? 24 LYS B N 1 ATOM 3417 C CA . LYS B 1 26 ? 179.753 53.210 8.582 1.00 48.92 ? 24 LYS B CA 1 ATOM 3418 C C . LYS B 1 26 ? 180.114 52.944 10.061 1.00 48.99 ? 24 LYS B C 1 ATOM 3419 O O . LYS B 1 26 ? 180.883 53.677 10.690 1.00 46.94 ? 24 LYS B O 1 ATOM 3420 C CB . LYS B 1 26 ? 180.470 52.185 7.686 1.00 52.10 ? 24 LYS B CB 1 ATOM 3421 C CG . LYS B 1 26 ? 179.769 51.852 6.381 1.00 62.85 ? 24 LYS B CG 1 ATOM 3422 C CD . LYS B 1 26 ? 180.728 51.088 5.467 1.00 73.39 ? 24 LYS B CD 1 ATOM 3423 C CE . LYS B 1 26 ? 180.097 50.705 4.150 1.00 86.45 ? 24 LYS B CE 1 ATOM 3424 N NZ . LYS B 1 26 ? 180.975 49.806 3.352 1.00 92.49 ? 24 LYS B NZ 1 ATOM 3425 N N . VAL B 1 27 ? 179.520 51.880 10.607 1.00 45.18 ? 25 VAL B N 1 ATOM 3426 C CA . VAL B 1 27 ? 179.700 51.452 11.998 1.00 43.97 ? 25 VAL B CA 1 ATOM 3427 C C . VAL B 1 27 ? 179.609 49.940 12.117 1.00 44.47 ? 25 VAL B C 1 ATOM 3428 O O . VAL B 1 27 ? 178.709 49.312 11.557 1.00 45.14 ? 25 VAL B O 1 ATOM 3429 C CB . VAL B 1 27 ? 178.765 52.194 13.008 1.00 47.72 ? 25 VAL B CB 1 ATOM 3430 C CG1 . VAL B 1 27 ? 177.333 52.271 12.506 1.00 47.86 ? 25 VAL B CG1 1 ATOM 3431 C CG2 . VAL B 1 27 ? 178.808 51.572 14.407 1.00 47.29 ? 25 VAL B CG2 1 ATOM 3432 N N . LEU B 1 28 ? 180.553 49.370 12.857 1.00 37.24 ? 26 LEU B N 1 ATOM 3433 C CA . LEU B 1 28 ? 180.595 47.961 13.192 1.00 34.55 ? 26 LEU B CA 1 ATOM 3434 C C . LEU B 1 28 ? 179.725 47.818 14.459 1.00 36.13 ? 26 LEU B C 1 ATOM 3435 O O . LEU B 1 28 ? 180.053 48.410 15.479 1.00 33.33 ? 26 LEU B O 1 ATOM 3436 C CB . LEU B 1 28 ? 182.059 47.579 13.487 1.00 33.32 ? 26 LEU B CB 1 ATOM 3437 C CG . LEU B 1 28 ? 182.434 46.110 13.427 1.00 35.61 ? 26 LEU B CG 1 ATOM 3438 C CD1 . LEU B 1 28 ? 183.908 45.959 13.079 1.00 35.89 ? 26 LEU B CD1 1 ATOM 3439 C CD2 . LEU B 1 28 ? 182.104 45.377 14.723 1.00 32.45 ? 26 LEU B CD2 1 ATOM 3440 N N . THR B 1 29 ? 178.607 47.072 14.371 1.00 34.51 ? 27 THR B N 1 ATOM 3441 C CA . THR B 1 29 ? 177.707 46.787 15.501 1.00 35.03 ? 27 THR B CA 1 ATOM 3442 C C . THR B 1 29 ? 177.638 45.278 15.753 1.00 40.71 ? 27 THR B C 1 ATOM 3443 O O . THR B 1 29 ? 177.351 44.504 14.842 1.00 42.88 ? 27 THR B O 1 ATOM 3444 C CB . THR B 1 29 ? 176.285 47.370 15.279 1.00 44.49 ? 27 THR B CB 1 ATOM 3445 O OG1 . THR B 1 29 ? 176.327 48.795 15.340 1.00 46.41 ? 27 THR B OG1 1 ATOM 3446 C CG2 . THR B 1 29 ? 175.274 46.875 16.320 1.00 44.71 ? 27 THR B CG2 1 ATOM 3447 N N . LEU B 1 30 ? 177.877 44.874 16.991 1.00 35.27 ? 28 LEU B N 1 ATOM 3448 C CA . LEU B 1 30 ? 177.756 43.500 17.462 1.00 33.60 ? 28 LEU B CA 1 ATOM 3449 C C . LEU B 1 30 ? 176.848 43.530 18.700 1.00 37.91 ? 28 LEU B C 1 ATOM 3450 O O . LEU B 1 30 ? 176.929 44.461 19.511 1.00 36.23 ? 28 LEU B O 1 ATOM 3451 C CB . LEU B 1 30 ? 179.127 42.900 17.819 1.00 32.88 ? 28 LEU B CB 1 ATOM 3452 C CG . LEU B 1 30 ? 180.154 42.679 16.693 1.00 36.00 ? 28 LEU B CG 1 ATOM 3453 C CD1 . LEU B 1 30 ? 181.412 42.039 17.249 1.00 35.89 ? 28 LEU B CD1 1 ATOM 3454 C CD2 . LEU B 1 30 ? 179.629 41.769 15.619 1.00 34.77 ? 28 LEU B CD2 1 ATOM 3455 N N . GLU B 1 31 ? 175.971 42.535 18.829 1.00 36.81 ? 29 GLU B N 1 ATOM 3456 C CA . GLU B 1 31 ? 175.039 42.456 19.949 1.00 37.69 ? 29 GLU B CA 1 ATOM 3457 C C . GLU B 1 31 ? 175.683 41.839 21.183 1.00 38.95 ? 29 GLU B C 1 ATOM 3458 O O . GLU B 1 31 ? 176.508 40.918 21.075 1.00 37.67 ? 29 GLU B O 1 ATOM 3459 C CB . GLU B 1 31 ? 173.790 41.641 19.579 1.00 40.25 ? 29 GLU B CB 1 ATOM 3460 C CG . GLU B 1 31 ? 172.904 42.241 18.498 1.00 61.41 ? 29 GLU B CG 1 ATOM 3461 C CD . GLU B 1 31 ? 172.055 41.192 17.788 1.00 100.50 ? 29 GLU B CD 1 ATOM 3462 O OE1 . GLU B 1 31 ? 170.889 40.989 18.201 1.00 99.76 ? 29 GLU B OE1 1 ATOM 3463 O OE2 . GLU B 1 31 ? 172.567 40.552 16.838 1.00 96.19 ? 29 GLU B OE2 1 ATOM 3464 N N . GLY B 1 32 ? 175.253 42.336 22.339 1.00 34.10 ? 30 GLY B N 1 ATOM 3465 C CA . GLY B 1 32 ? 175.648 41.855 23.653 1.00 33.56 ? 30 GLY B CA 1 ATOM 3466 C C . GLY B 1 32 ? 174.741 42.374 24.749 1.00 38.20 ? 30 GLY B C 1 ATOM 3467 O O . GLY B 1 32 ? 173.906 43.251 24.510 1.00 37.11 ? 30 GLY B O 1 ATOM 3468 N N . ASP B 1 33 ? 174.927 41.861 25.981 1.00 36.06 ? 31 ASP B N 1 ATOM 3469 C CA . ASP B 1 33 ? 174.216 42.325 27.179 1.00 35.76 ? 31 ASP B CA 1 ATOM 3470 C C . ASP B 1 33 ? 174.798 43.661 27.588 1.00 36.95 ? 31 ASP B C 1 ATOM 3471 O O . ASP B 1 33 ? 174.118 44.491 28.202 1.00 36.26 ? 31 ASP B O 1 ATOM 3472 C CB . ASP B 1 33 ? 174.403 41.325 28.317 1.00 38.70 ? 31 ASP B CB 1 ATOM 3473 C CG . ASP B 1 33 ? 173.816 39.974 28.009 1.00 47.41 ? 31 ASP B CG 1 ATOM 3474 O OD1 . ASP B 1 33 ? 172.584 39.906 27.766 1.00 50.56 ? 31 ASP B OD1 1 ATOM 3475 O OD2 . ASP B 1 33 ? 174.582 38.983 28.006 1.00 44.66 ? 31 ASP B OD2 1 ATOM 3476 N N . LEU B 1 34 ? 176.085 43.844 27.252 1.00 31.84 ? 32 LEU B N 1 ATOM 3477 C CA . LEU B 1 34 ? 176.861 45.057 27.463 1.00 30.88 ? 32 LEU B CA 1 ATOM 3478 C C . LEU B 1 34 ? 177.588 45.345 26.166 1.00 34.27 ? 32 LEU B C 1 ATOM 3479 O O . LEU B 1 34 ? 178.117 44.429 25.517 1.00 32.61 ? 32 LEU B O 1 ATOM 3480 C CB . LEU B 1 34 ? 177.853 44.929 28.649 1.00 30.62 ? 32 LEU B CB 1 ATOM 3481 C CG . LEU B 1 34 ? 177.255 44.741 30.072 1.00 33.12 ? 32 LEU B CG 1 ATOM 3482 C CD1 . LEU B 1 34 ? 178.324 44.365 31.065 1.00 32.19 ? 32 LEU B CD1 1 ATOM 3483 C CD2 . LEU B 1 34 ? 176.527 45.966 30.536 1.00 31.13 ? 32 LEU B CD2 1 ATOM 3484 N N . VAL B 1 35 ? 177.571 46.626 25.764 1.00 31.61 ? 33 VAL B N 1 ATOM 3485 C CA . VAL B 1 35 ? 178.161 47.055 24.498 1.00 30.27 ? 33 VAL B CA 1 ATOM 3486 C C . VAL B 1 35 ? 179.360 47.919 24.757 1.00 31.49 ? 33 VAL B C 1 ATOM 3487 O O . VAL B 1 35 ? 179.256 48.969 25.416 1.00 30.44 ? 33 VAL B O 1 ATOM 3488 C CB . VAL B 1 35 ? 177.127 47.722 23.530 1.00 33.03 ? 33 VAL B CB 1 ATOM 3489 C CG1 . VAL B 1 35 ? 177.780 48.127 22.210 1.00 32.40 ? 33 VAL B CG1 1 ATOM 3490 C CG2 . VAL B 1 35 ? 175.953 46.790 23.261 1.00 32.68 ? 33 VAL B CG2 1 ATOM 3491 N N . LEU B 1 36 ? 180.506 47.462 24.225 1.00 26.97 ? 34 LEU B N 1 ATOM 3492 C CA . LEU B 1 36 ? 181.764 48.189 24.305 1.00 26.75 ? 34 LEU B CA 1 ATOM 3493 C C . LEU B 1 36 ? 181.968 49.007 23.059 1.00 27.53 ? 34 LEU B C 1 ATOM 3494 O O . LEU B 1 36 ? 181.915 48.482 21.937 1.00 26.98 ? 34 LEU B O 1 ATOM 3495 C CB . LEU B 1 36 ? 182.966 47.251 24.513 1.00 27.48 ? 34 LEU B CB 1 ATOM 3496 C CG . LEU B 1 36 ? 183.056 46.508 25.849 1.00 33.68 ? 34 LEU B CG 1 ATOM 3497 C CD1 . LEU B 1 36 ? 184.478 46.000 26.064 1.00 33.96 ? 34 LEU B CD1 1 ATOM 3498 C CD2 . LEU B 1 36 ? 182.584 47.393 27.063 1.00 36.95 ? 34 LEU B CD2 1 ATOM 3499 N N . GLY B 1 37 ? 182.182 50.296 23.269 1.00 21.51 ? 35 GLY B N 1 ATOM 3500 C CA . GLY B 1 37 ? 182.494 51.230 22.204 1.00 19.82 ? 35 GLY B CA 1 ATOM 3501 C C . GLY B 1 37 ? 183.897 50.964 21.708 1.00 21.17 ? 35 GLY B C 1 ATOM 3502 O O . GLY B 1 37 ? 184.750 50.443 22.427 1.00 18.95 ? 35 GLY B O 1 ATOM 3503 N N . GLY B 1 38 ? 184.135 51.292 20.467 1.00 19.21 ? 36 GLY B N 1 ATOM 3504 C CA . GLY B 1 38 ? 185.458 51.116 19.889 1.00 18.64 ? 36 GLY B CA 1 ATOM 3505 C C . GLY B 1 38 ? 185.803 52.305 19.044 1.00 19.96 ? 36 GLY B C 1 ATOM 3506 O O . GLY B 1 38 ? 184.914 52.924 18.475 1.00 19.18 ? 36 GLY B O 1 ATOM 3507 N N . LEU B 1 39 ? 187.070 52.648 18.983 1.00 16.34 ? 37 LEU B N 1 ATOM 3508 C CA . LEU B 1 39 ? 187.522 53.742 18.134 1.00 16.01 ? 37 LEU B CA 1 ATOM 3509 C C . LEU B 1 39 ? 188.897 53.416 17.549 1.00 15.94 ? 37 LEU B C 1 ATOM 3510 O O . LEU B 1 39 ? 189.856 53.168 18.281 1.00 12.08 ? 37 LEU B O 1 ATOM 3511 C CB . LEU B 1 39 ? 187.438 55.113 18.846 1.00 16.40 ? 37 LEU B CB 1 ATOM 3512 C CG . LEU B 1 39 ? 187.404 56.392 17.979 1.00 21.78 ? 37 LEU B CG 1 ATOM 3513 C CD1 . LEU B 1 39 ? 186.106 56.525 17.182 1.00 19.96 ? 37 LEU B CD1 1 ATOM 3514 C CD2 . LEU B 1 39 ? 187.534 57.628 18.877 1.00 26.12 ? 37 LEU B CD2 1 ATOM 3515 N N . PHE B 1 40 ? 188.940 53.295 16.219 1.00 14.27 ? 38 PHE B N 1 ATOM 3516 C CA . PHE B 1 40 ? 190.149 52.934 15.466 1.00 14.75 ? 38 PHE B CA 1 ATOM 3517 C C . PHE B 1 40 ? 190.334 53.835 14.286 1.00 18.19 ? 38 PHE B C 1 ATOM 3518 O O . PHE B 1 40 ? 189.334 54.280 13.713 1.00 18.29 ? 38 PHE B O 1 ATOM 3519 C CB . PHE B 1 40 ? 190.117 51.433 14.995 1.00 15.71 ? 38 PHE B CB 1 ATOM 3520 C CG . PHE B 1 40 ? 189.988 50.475 16.163 1.00 15.21 ? 38 PHE B CG 1 ATOM 3521 C CD1 . PHE B 1 40 ? 188.735 50.164 16.695 1.00 15.00 ? 38 PHE B CD1 1 ATOM 3522 C CD2 . PHE B 1 40 ? 191.119 49.961 16.787 1.00 15.82 ? 38 PHE B CD2 1 ATOM 3523 C CE1 . PHE B 1 40 ? 188.614 49.387 17.847 1.00 15.47 ? 38 PHE B CE1 1 ATOM 3524 C CE2 . PHE B 1 40 ? 191.003 49.181 17.944 1.00 18.30 ? 38 PHE B CE2 1 ATOM 3525 C CZ . PHE B 1 40 ? 189.749 48.911 18.474 1.00 16.52 ? 38 PHE B CZ 1 ATOM 3526 N N . PRO B 1 41 ? 191.592 54.108 13.873 1.00 14.24 ? 39 PRO B N 1 ATOM 3527 C CA . PRO B 1 41 ? 191.791 54.892 12.650 1.00 13.82 ? 39 PRO B CA 1 ATOM 3528 C C . PRO B 1 41 ? 191.713 53.935 11.457 1.00 21.35 ? 39 PRO B C 1 ATOM 3529 O O . PRO B 1 41 ? 192.743 53.633 10.842 1.00 23.30 ? 39 PRO B O 1 ATOM 3530 C CB . PRO B 1 41 ? 193.189 55.484 12.856 1.00 14.84 ? 39 PRO B CB 1 ATOM 3531 C CG . PRO B 1 41 ? 193.924 54.420 13.649 1.00 19.41 ? 39 PRO B CG 1 ATOM 3532 C CD . PRO B 1 41 ? 192.886 53.644 14.426 1.00 15.66 ? 39 PRO B CD 1 ATOM 3533 N N . VAL B 1 42 ? 190.519 53.398 11.154 1.00 19.30 ? 40 VAL B N 1 ATOM 3534 C CA . VAL B 1 42 ? 190.377 52.449 10.019 1.00 20.08 ? 40 VAL B CA 1 ATOM 3535 C C . VAL B 1 42 ? 190.901 53.104 8.707 1.00 24.60 ? 40 VAL B C 1 ATOM 3536 O O . VAL B 1 42 ? 191.518 52.417 7.883 1.00 23.34 ? 40 VAL B O 1 ATOM 3537 C CB . VAL B 1 42 ? 188.930 51.924 9.840 1.00 22.56 ? 40 VAL B CB 1 ATOM 3538 C CG1 . VAL B 1 42 ? 188.867 50.822 8.783 1.00 21.39 ? 40 VAL B CG1 1 ATOM 3539 C CG2 . VAL B 1 42 ? 188.338 51.467 11.169 1.00 21.75 ? 40 VAL B CG2 1 ATOM 3540 N N . HIS B 1 43 ? 190.695 54.438 8.566 1.00 20.80 ? 41 HIS B N 1 ATOM 3541 C CA . HIS B 1 43 ? 191.156 55.185 7.403 1.00 21.67 ? 41 HIS B CA 1 ATOM 3542 C C . HIS B 1 43 ? 192.166 56.214 7.768 1.00 26.92 ? 41 HIS B C 1 ATOM 3543 O O . HIS B 1 43 ? 192.184 56.705 8.896 1.00 24.99 ? 41 HIS B O 1 ATOM 3544 C CB . HIS B 1 43 ? 189.987 55.880 6.654 1.00 22.49 ? 41 HIS B CB 1 ATOM 3545 C CG . HIS B 1 43 ? 189.075 54.928 5.960 1.00 25.47 ? 41 HIS B CG 1 ATOM 3546 N ND1 . HIS B 1 43 ? 187.959 54.429 6.582 1.00 26.81 ? 41 HIS B ND1 1 ATOM 3547 C CD2 . HIS B 1 43 ? 189.185 54.365 4.741 1.00 27.32 ? 41 HIS B CD2 1 ATOM 3548 C CE1 . HIS B 1 43 ? 187.397 53.610 5.715 1.00 26.43 ? 41 HIS B CE1 1 ATOM 3549 N NE2 . HIS B 1 43 ? 188.098 53.545 4.590 1.00 26.93 ? 41 HIS B NE2 1 ATOM 3550 N N . GLN B 1 44 ? 192.983 56.588 6.772 1.00 26.18 ? 42 GLN B N 1 ATOM 3551 C CA . GLN B 1 44 ? 193.923 57.693 6.876 1.00 27.14 ? 42 GLN B CA 1 ATOM 3552 C C . GLN B 1 44 ? 193.084 58.981 6.761 1.00 31.52 ? 42 GLN B C 1 ATOM 3553 O O . GLN B 1 44 ? 191.890 58.924 6.427 1.00 29.05 ? 42 GLN B O 1 ATOM 3554 C CB . GLN B 1 44 ? 194.941 57.620 5.726 1.00 28.78 ? 42 GLN B CB 1 ATOM 3555 C CG . GLN B 1 44 ? 196.037 56.571 5.965 1.00 52.19 ? 42 GLN B CG 1 ATOM 3556 C CD . GLN B 1 44 ? 196.744 56.183 4.690 1.00 76.23 ? 42 GLN B CD 1 ATOM 3557 O OE1 . GLN B 1 44 ? 197.389 57.010 4.024 1.00 69.62 ? 42 GLN B OE1 1 ATOM 3558 N NE2 . GLN B 1 44 ? 196.642 54.908 4.322 1.00 70.52 ? 42 GLN B NE2 1 ATOM 3559 N N . LYS B 1 45 ? 193.693 60.133 7.038 1.00 30.63 ? 43 LYS B N 1 ATOM 3560 C CA . LYS B 1 45 ? 192.973 61.389 6.888 1.00 31.95 ? 43 LYS B CA 1 ATOM 3561 C C . LYS B 1 45 ? 192.801 61.706 5.415 1.00 42.28 ? 43 LYS B C 1 ATOM 3562 O O . LYS B 1 45 ? 193.626 61.307 4.572 1.00 41.21 ? 43 LYS B O 1 ATOM 3563 C CB . LYS B 1 45 ? 193.649 62.540 7.658 1.00 34.41 ? 43 LYS B CB 1 ATOM 3564 C CG . LYS B 1 45 ? 195.086 62.869 7.263 1.00 39.44 ? 43 LYS B CG 1 ATOM 3565 C CD . LYS B 1 45 ? 195.721 63.787 8.279 1.00 46.46 ? 43 LYS B CD 1 ATOM 3566 C CE . LYS B 1 45 ? 197.116 64.197 7.843 1.00 63.70 ? 43 LYS B CE 1 ATOM 3567 N NZ . LYS B 1 45 ? 197.872 64.870 8.945 1.00 70.61 ? 43 LYS B NZ 1 ATOM 3568 N N . GLY B 1 46 ? 191.708 62.400 5.117 1.00 45.03 ? 44 GLY B N 1 ATOM 3569 C CA . GLY B 1 46 ? 191.369 62.849 3.766 1.00 46.63 ? 44 GLY B CA 1 ATOM 3570 C C . GLY B 1 46 ? 192.368 63.821 3.162 1.00 53.43 ? 44 GLY B C 1 ATOM 3571 O O . GLY B 1 46 ? 193.335 64.235 3.813 1.00 50.47 ? 44 GLY B O 1 ATOM 3572 N N . GLY B 1 47 ? 192.139 64.161 1.900 1.00 55.63 ? 45 GLY B N 1 ATOM 3573 C CA . GLY B 1 47 ? 193.000 65.082 1.168 1.00 57.71 ? 45 GLY B CA 1 ATOM 3574 C C . GLY B 1 47 ? 192.524 66.513 1.310 1.00 66.13 ? 45 GLY B C 1 ATOM 3575 O O . GLY B 1 47 ? 191.885 66.854 2.320 1.00 65.56 ? 45 GLY B O 1 ATOM 3576 N N . PRO B 1 48 ? 192.797 67.378 0.294 1.00 65.62 ? 46 PRO B N 1 ATOM 3577 C CA . PRO B 1 48 ? 192.304 68.770 0.366 1.00 65.32 ? 46 PRO B CA 1 ATOM 3578 C C . PRO B 1 48 ? 190.781 68.785 0.266 1.00 67.80 ? 46 PRO B C 1 ATOM 3579 O O . PRO B 1 48 ? 190.130 69.566 0.961 1.00 67.69 ? 46 PRO B O 1 ATOM 3580 C CB . PRO B 1 48 ? 192.971 69.458 -0.838 1.00 67.05 ? 46 PRO B CB 1 ATOM 3581 C CG . PRO B 1 48 ? 194.049 68.508 -1.305 1.00 71.84 ? 46 PRO B CG 1 ATOM 3582 C CD . PRO B 1 48 ? 193.529 67.139 -0.968 1.00 67.57 ? 46 PRO B CD 1 ATOM 3583 N N . ALA B 1 49 ? 190.223 67.831 -0.509 1.00 62.69 ? 47 ALA B N 1 ATOM 3584 C CA . ALA B 1 49 ? 188.792 67.677 -0.736 1.00 62.60 ? 47 ALA B CA 1 ATOM 3585 C C . ALA B 1 49 ? 188.040 66.889 0.345 1.00 66.44 ? 47 ALA B C 1 ATOM 3586 O O . ALA B 1 49 ? 187.139 67.446 0.987 1.00 65.43 ? 47 ALA B O 1 ATOM 3587 C CB . ALA B 1 49 ? 188.552 67.040 -2.101 1.00 63.32 ? 47 ALA B CB 1 ATOM 3588 N N . GLU B 1 50 ? 188.409 65.587 0.516 1.00 62.57 ? 48 GLU B N 1 ATOM 3589 C CA . GLU B 1 50 ? 187.762 64.576 1.370 1.00 61.54 ? 48 GLU B CA 1 ATOM 3590 C C . GLU B 1 50 ? 188.101 64.592 2.860 1.00 61.91 ? 48 GLU B C 1 ATOM 3591 O O . GLU B 1 50 ? 189.132 65.136 3.269 1.00 60.73 ? 48 GLU B O 1 ATOM 3592 C CB . GLU B 1 50 ? 188.048 63.164 0.818 1.00 62.89 ? 48 GLU B CB 1 ATOM 3593 N N . ASP B 1 51 ? 187.218 63.932 3.659 1.00 56.49 ? 49 ASP B N 1 ATOM 3594 C CA . ASP B 1 51 ? 187.352 63.744 5.105 1.00 55.80 ? 49 ASP B CA 1 ATOM 3595 C C . ASP B 1 51 ? 188.170 62.476 5.416 1.00 55.33 ? 49 ASP B C 1 ATOM 3596 O O . ASP B 1 51 ? 189.033 62.501 6.298 1.00 55.39 ? 49 ASP B O 1 ATOM 3597 C CB . ASP B 1 51 ? 185.969 63.676 5.792 1.00 58.55 ? 49 ASP B CB 1 ATOM 3598 C CG . ASP B 1 51 ? 185.975 64.011 7.288 1.00 73.07 ? 49 ASP B CG 1 ATOM 3599 O OD1 . ASP B 1 51 ? 187.063 63.973 7.906 1.00 73.17 ? 49 ASP B OD1 1 ATOM 3600 O OD2 . ASP B 1 51 ? 184.883 64.303 7.841 1.00 80.98 ? 49 ASP B OD2 1 ATOM 3601 N N . CYS B 1 52 ? 187.893 61.369 4.694 1.00 46.42 ? 50 CYS B N 1 ATOM 3602 C CA . CYS B 1 52 ? 188.620 60.131 4.893 1.00 43.19 ? 50 CYS B CA 1 ATOM 3603 C C . CYS B 1 52 ? 189.425 59.768 3.659 1.00 42.42 ? 50 CYS B C 1 ATOM 3604 O O . CYS B 1 52 ? 189.018 60.052 2.543 1.00 41.68 ? 50 CYS B O 1 ATOM 3605 C CB . CYS B 1 52 ? 187.686 59.009 5.339 1.00 43.28 ? 50 CYS B CB 1 ATOM 3606 S SG . CYS B 1 52 ? 186.693 59.428 6.815 1.00 47.02 ? 50 CYS B SG 1 ATOM 3607 N N . GLY B 1 53 ? 190.608 59.229 3.892 1.00 36.85 ? 51 GLY B N 1 ATOM 3608 C CA . GLY B 1 53 ? 191.532 58.796 2.859 1.00 34.85 ? 51 GLY B CA 1 ATOM 3609 C C . GLY B 1 53 ? 191.604 57.282 2.711 1.00 34.22 ? 51 GLY B C 1 ATOM 3610 O O . GLY B 1 53 ? 190.640 56.564 3.012 1.00 32.27 ? 51 GLY B O 1 ATOM 3611 N N . PRO B 1 54 ? 192.742 56.749 2.239 1.00 28.89 ? 52 PRO B N 1 ATOM 3612 C CA . PRO B 1 54 ? 192.836 55.295 2.062 1.00 28.77 ? 52 PRO B CA 1 ATOM 3613 C C . PRO B 1 54 ? 192.898 54.519 3.379 1.00 34.25 ? 52 PRO B C 1 ATOM 3614 O O . PRO B 1 54 ? 193.299 55.059 4.416 1.00 35.21 ? 52 PRO B O 1 ATOM 3615 C CB . PRO B 1 54 ? 194.099 55.145 1.231 1.00 29.81 ? 52 PRO B CB 1 ATOM 3616 C CG . PRO B 1 54 ? 194.944 56.282 1.680 1.00 33.66 ? 52 PRO B CG 1 ATOM 3617 C CD . PRO B 1 54 ? 194.000 57.415 1.856 1.00 29.07 ? 52 PRO B CD 1 ATOM 3618 N N . VAL B 1 55 ? 192.498 53.245 3.323 1.00 30.22 ? 53 VAL B N 1 ATOM 3619 C CA . VAL B 1 55 ? 192.462 52.300 4.442 1.00 28.85 ? 53 VAL B CA 1 ATOM 3620 C C . VAL B 1 55 ? 193.861 52.151 5.072 1.00 34.40 ? 53 VAL B C 1 ATOM 3621 O O . VAL B 1 55 ? 194.879 52.232 4.386 1.00 32.48 ? 53 VAL B O 1 ATOM 3622 C CB . VAL B 1 55 ? 191.833 50.939 4.014 1.00 31.03 ? 53 VAL B CB 1 ATOM 3623 C CG1 . VAL B 1 55 ? 191.877 49.917 5.134 1.00 30.44 ? 53 VAL B CG1 1 ATOM 3624 C CG2 . VAL B 1 55 ? 190.398 51.120 3.531 1.00 30.60 ? 53 VAL B CG2 1 ATOM 3625 N N . ASN B 1 56 ? 193.876 52.016 6.407 1.00 33.53 ? 54 ASN B N 1 ATOM 3626 C CA . ASN B 1 56 ? 195.035 51.813 7.260 1.00 33.39 ? 54 ASN B CA 1 ATOM 3627 C C . ASN B 1 56 ? 195.058 50.321 7.527 1.00 38.84 ? 54 ASN B C 1 ATOM 3628 O O . ASN B 1 56 ? 194.270 49.819 8.330 1.00 36.98 ? 54 ASN B O 1 ATOM 3629 C CB . ASN B 1 56 ? 194.810 52.553 8.566 1.00 32.43 ? 54 ASN B CB 1 ATOM 3630 C CG . ASN B 1 56 ? 195.765 53.628 8.862 1.00 53.64 ? 54 ASN B CG 1 ATOM 3631 O OD1 . ASN B 1 56 ? 196.723 53.860 8.137 1.00 57.64 ? 54 ASN B OD1 1 ATOM 3632 N ND2 . ASN B 1 56 ? 195.504 54.321 9.948 1.00 52.95 ? 54 ASN B ND2 1 ATOM 3633 N N . GLU B 1 57 ? 195.902 49.599 6.800 1.00 39.62 ? 55 GLU B N 1 ATOM 3634 C CA . GLU B 1 57 ? 195.965 48.139 6.915 1.00 40.73 ? 55 GLU B CA 1 ATOM 3635 C C . GLU B 1 57 ? 196.439 47.664 8.299 1.00 46.06 ? 55 GLU B C 1 ATOM 3636 O O . GLU B 1 57 ? 195.806 46.789 8.898 1.00 46.05 ? 55 GLU B O 1 ATOM 3637 C CB . GLU B 1 57 ? 196.816 47.518 5.783 1.00 42.27 ? 55 GLU B CB 1 ATOM 3638 C CG . GLU B 1 57 ? 196.469 47.993 4.367 1.00 57.76 ? 55 GLU B CG 1 ATOM 3639 C CD . GLU B 1 57 ? 197.317 47.452 3.216 1.00 84.49 ? 55 GLU B CD 1 ATOM 3640 O OE1 . GLU B 1 57 ? 197.126 47.915 2.063 1.00 53.32 ? 55 GLU B OE1 1 ATOM 3641 O OE2 . GLU B 1 57 ? 198.175 46.570 3.465 1.00 84.98 ? 55 GLU B OE2 1 ATOM 3642 N N . HIS B 1 58 ? 197.507 48.272 8.821 1.00 43.07 ? 56 HIS B N 1 ATOM 3643 C CA . HIS B 1 58 ? 198.117 47.831 10.063 1.00 43.38 ? 56 HIS B CA 1 ATOM 3644 C C . HIS B 1 58 ? 197.564 48.433 11.322 1.00 42.55 ? 56 HIS B C 1 ATOM 3645 O O . HIS B 1 58 ? 197.207 47.683 12.235 1.00 43.28 ? 56 HIS B O 1 ATOM 3646 C CB . HIS B 1 58 ? 199.633 48.037 10.007 1.00 45.93 ? 56 HIS B CB 1 ATOM 3647 C CG . HIS B 1 58 ? 200.292 46.994 9.182 1.00 51.00 ? 56 HIS B CG 1 ATOM 3648 N ND1 . HIS B 1 58 ? 200.807 45.845 9.759 1.00 53.88 ? 56 HIS B ND1 1 ATOM 3649 C CD2 . HIS B 1 58 ? 200.393 46.898 7.833 1.00 54.33 ? 56 HIS B CD2 1 ATOM 3650 C CE1 . HIS B 1 58 ? 201.258 45.111 8.749 1.00 54.27 ? 56 HIS B CE1 1 ATOM 3651 N NE2 . HIS B 1 58 ? 201.038 45.709 7.569 1.00 54.56 ? 56 HIS B NE2 1 ATOM 3652 N N . ARG B 1 59 ? 197.556 49.762 11.433 1.00 34.03 ? 57 ARG B N 1 ATOM 3653 C CA . ARG B 1 59 ? 197.074 50.359 12.671 1.00 31.62 ? 57 ARG B CA 1 ATOM 3654 C C . ARG B 1 59 ? 195.545 50.616 12.635 1.00 33.00 ? 57 ARG B C 1 ATOM 3655 O O . ARG B 1 59 ? 194.952 51.082 13.619 1.00 31.36 ? 57 ARG B O 1 ATOM 3656 C CB . ARG B 1 59 ? 197.900 51.595 13.038 1.00 28.92 ? 57 ARG B CB 1 ATOM 3657 C CG . ARG B 1 59 ? 199.380 51.294 13.232 1.00 29.56 ? 57 ARG B CG 1 ATOM 3658 C CD . ARG B 1 59 ? 200.163 52.569 13.369 1.00 32.59 ? 57 ARG B CD 1 ATOM 3659 N NE . ARG B 1 59 ? 201.429 52.382 14.072 1.00 38.23 ? 57 ARG B NE 1 ATOM 3660 C CZ . ARG B 1 59 ? 202.230 53.381 14.421 1.00 50.62 ? 57 ARG B CZ 1 ATOM 3661 N NH1 . ARG B 1 59 ? 201.901 54.634 14.135 1.00 40.52 ? 57 ARG B NH1 1 ATOM 3662 N NH2 . ARG B 1 59 ? 203.357 53.137 15.077 1.00 37.96 ? 57 ARG B NH2 1 ATOM 3663 N N . GLY B 1 60 ? 194.922 50.257 11.521 1.00 28.08 ? 58 GLY B N 1 ATOM 3664 C CA . GLY B 1 60 ? 193.488 50.400 11.384 1.00 28.19 ? 58 GLY B CA 1 ATOM 3665 C C . GLY B 1 60 ? 192.811 49.056 11.512 1.00 33.57 ? 58 GLY B C 1 ATOM 3666 O O . GLY B 1 60 ? 192.321 48.691 12.587 1.00 34.80 ? 58 GLY B O 1 ATOM 3667 N N . ILE B 1 61 ? 192.820 48.311 10.413 1.00 28.14 ? 59 ILE B N 1 ATOM 3668 C CA . ILE B 1 61 ? 192.196 47.009 10.263 1.00 28.03 ? 59 ILE B CA 1 ATOM 3669 C C . ILE B 1 61 ? 192.710 45.957 11.286 1.00 27.68 ? 59 ILE B C 1 ATOM 3670 O O . ILE B 1 61 ? 191.900 45.302 11.960 1.00 26.34 ? 59 ILE B O 1 ATOM 3671 C CB . ILE B 1 61 ? 192.354 46.559 8.766 1.00 31.65 ? 59 ILE B CB 1 ATOM 3672 C CG1 . ILE B 1 61 ? 191.413 47.374 7.831 1.00 31.25 ? 59 ILE B CG1 1 ATOM 3673 C CG2 . ILE B 1 61 ? 192.201 45.027 8.557 1.00 32.94 ? 59 ILE B CG2 1 ATOM 3674 C CD1 . ILE B 1 61 ? 189.877 47.170 8.022 1.00 36.61 ? 59 ILE B CD1 1 ATOM 3675 N N . GLN B 1 62 ? 194.025 45.802 11.383 1.00 22.16 ? 60 GLN B N 1 ATOM 3676 C CA . GLN B 1 62 ? 194.634 44.811 12.267 1.00 22.85 ? 60 GLN B CA 1 ATOM 3677 C C . GLN B 1 62 ? 194.308 45.110 13.713 1.00 26.56 ? 60 GLN B C 1 ATOM 3678 O O . GLN B 1 62 ? 193.960 44.182 14.431 1.00 25.89 ? 60 GLN B O 1 ATOM 3679 C CB . GLN B 1 62 ? 196.151 44.736 12.044 1.00 24.75 ? 60 GLN B CB 1 ATOM 3680 C CG . GLN B 1 62 ? 196.678 43.415 11.532 1.00 27.69 ? 60 GLN B CG 1 ATOM 3681 C CD . GLN B 1 62 ? 198.146 43.252 11.909 1.00 43.21 ? 60 GLN B CD 1 ATOM 3682 O OE1 . GLN B 1 62 ? 198.511 43.064 13.084 1.00 37.70 ? 60 GLN B OE1 1 ATOM 3683 N NE2 . GLN B 1 62 ? 199.018 43.271 10.915 1.00 26.44 ? 60 GLN B NE2 1 ATOM 3684 N N . ARG B 1 63 ? 194.340 46.413 14.131 1.00 22.89 ? 61 ARG B N 1 ATOM 3685 C CA . ARG B 1 63 ? 193.991 46.804 15.507 1.00 21.37 ? 61 ARG B CA 1 ATOM 3686 C C . ARG B 1 63 ? 192.536 46.603 15.798 1.00 26.30 ? 61 ARG B C 1 ATOM 3687 O O . ARG B 1 63 ? 192.179 46.131 16.868 1.00 27.86 ? 61 ARG B O 1 ATOM 3688 C CB . ARG B 1 63 ? 194.404 48.231 15.797 1.00 20.42 ? 61 ARG B CB 1 ATOM 3689 C CG . ARG B 1 63 ? 195.881 48.365 16.054 1.00 22.66 ? 61 ARG B CG 1 ATOM 3690 C CD . ARG B 1 63 ? 196.195 49.767 16.454 1.00 25.73 ? 61 ARG B CD 1 ATOM 3691 N NE . ARG B 1 63 ? 197.634 49.937 16.498 1.00 30.04 ? 61 ARG B NE 1 ATOM 3692 C CZ . ARG B 1 63 ? 198.238 51.099 16.646 1.00 34.35 ? 61 ARG B CZ 1 ATOM 3693 N NH1 . ARG B 1 63 ? 197.532 52.213 16.738 1.00 20.61 ? 61 ARG B NH1 1 ATOM 3694 N NH2 . ARG B 1 63 ? 199.563 51.161 16.677 1.00 23.10 ? 61 ARG B NH2 1 ATOM 3695 N N . LEU B 1 64 ? 191.684 46.925 14.842 1.00 23.20 ? 62 LEU B N 1 ATOM 3696 C CA . LEU B 1 64 ? 190.253 46.715 14.970 1.00 23.14 ? 62 LEU B CA 1 ATOM 3697 C C . LEU B 1 64 ? 189.980 45.196 15.098 1.00 27.08 ? 62 LEU B C 1 ATOM 3698 O O . LEU B 1 64 ? 189.139 44.790 15.908 1.00 27.62 ? 62 LEU B O 1 ATOM 3699 C CB . LEU B 1 64 ? 189.576 47.287 13.711 1.00 23.29 ? 62 LEU B CB 1 ATOM 3700 C CG . LEU B 1 64 ? 188.173 46.831 13.364 1.00 28.14 ? 62 LEU B CG 1 ATOM 3701 C CD1 . LEU B 1 64 ? 187.173 47.585 14.128 1.00 27.42 ? 62 LEU B CD1 1 ATOM 3702 C CD2 . LEU B 1 64 ? 187.903 47.061 11.930 1.00 34.92 ? 62 LEU B CD2 1 ATOM 3703 N N . GLU B 1 65 ? 190.682 44.369 14.292 1.00 20.83 ? 63 GLU B N 1 ATOM 3704 C CA . GLU B 1 65 ? 190.445 42.928 14.289 1.00 19.47 ? 63 GLU B CA 1 ATOM 3705 C C . GLU B 1 65 ? 190.839 42.319 15.595 1.00 25.17 ? 63 GLU B C 1 ATOM 3706 O O . GLU B 1 65 ? 190.143 41.410 16.078 1.00 24.11 ? 63 GLU B O 1 ATOM 3707 C CB . GLU B 1 65 ? 191.089 42.217 13.082 1.00 19.73 ? 63 GLU B CB 1 ATOM 3708 C CG . GLU B 1 65 ? 190.329 42.444 11.779 1.00 19.29 ? 63 GLU B CG 1 ATOM 3709 C CD . GLU B 1 65 ? 188.897 41.938 11.648 1.00 39.27 ? 63 GLU B CD 1 ATOM 3710 O OE1 . GLU B 1 65 ? 188.409 41.232 12.557 1.00 29.48 ? 63 GLU B OE1 1 ATOM 3711 O OE2 . GLU B 1 65 ? 188.247 42.273 10.633 1.00 40.16 ? 63 GLU B OE2 1 ATOM 3712 N N . ALA B 1 66 ? 191.900 42.901 16.217 1.00 21.07 ? 64 ALA B N 1 ATOM 3713 C CA . ALA B 1 66 ? 192.386 42.497 17.518 1.00 20.42 ? 64 ALA B CA 1 ATOM 3714 C C . ALA B 1 66 ? 191.292 42.689 18.594 1.00 26.93 ? 64 ALA B C 1 ATOM 3715 O O . ALA B 1 66 ? 191.159 41.816 19.452 1.00 28.53 ? 64 ALA B O 1 ATOM 3716 C CB . ALA B 1 66 ? 193.657 43.247 17.858 1.00 20.71 ? 64 ALA B CB 1 ATOM 3717 N N . MET B 1 67 ? 190.457 43.776 18.508 1.00 22.66 ? 65 MET B N 1 ATOM 3718 C CA . MET B 1 67 ? 189.326 44.026 19.427 1.00 20.43 ? 65 MET B CA 1 ATOM 3719 C C . MET B 1 67 ? 188.286 42.937 19.254 1.00 25.44 ? 65 MET B C 1 ATOM 3720 O O . MET B 1 67 ? 187.762 42.444 20.248 1.00 27.48 ? 65 MET B O 1 ATOM 3721 C CB . MET B 1 67 ? 188.703 45.413 19.178 1.00 21.90 ? 65 MET B CB 1 ATOM 3722 C CG . MET B 1 67 ? 187.330 45.632 19.852 1.00 24.28 ? 65 MET B CG 1 ATOM 3723 S SD . MET B 1 67 ? 187.155 47.322 20.487 1.00 27.39 ? 65 MET B SD 1 ATOM 3724 C CE . MET B 1 67 ? 185.519 47.264 21.290 1.00 22.61 ? 65 MET B CE 1 ATOM 3725 N N . LEU B 1 68 ? 187.991 42.555 17.990 1.00 21.59 ? 66 LEU B N 1 ATOM 3726 C CA . LEU B 1 68 ? 187.020 41.510 17.638 1.00 20.72 ? 66 LEU B CA 1 ATOM 3727 C C . LEU B 1 68 ? 187.472 40.136 18.095 1.00 26.89 ? 66 LEU B C 1 ATOM 3728 O O . LEU B 1 68 ? 186.715 39.434 18.753 1.00 28.17 ? 66 LEU B O 1 ATOM 3729 C CB . LEU B 1 68 ? 186.684 41.548 16.156 1.00 20.18 ? 66 LEU B CB 1 ATOM 3730 C CG . LEU B 1 68 ? 186.005 42.861 15.694 1.00 23.61 ? 66 LEU B CG 1 ATOM 3731 C CD1 . LEU B 1 68 ? 185.571 42.796 14.224 1.00 21.96 ? 66 LEU B CD1 1 ATOM 3732 C CD2 . LEU B 1 68 ? 184.835 43.215 16.580 1.00 24.96 ? 66 LEU B CD2 1 ATOM 3733 N N . PHE B 1 69 ? 188.732 39.796 17.830 1.00 23.70 ? 67 PHE B N 1 ATOM 3734 C CA . PHE B 1 69 ? 189.400 38.591 18.277 1.00 23.03 ? 67 PHE B CA 1 ATOM 3735 C C . PHE B 1 69 ? 189.252 38.519 19.826 1.00 31.00 ? 67 PHE B C 1 ATOM 3736 O O . PHE B 1 69 ? 188.763 37.502 20.367 1.00 30.94 ? 67 PHE B O 1 ATOM 3737 C CB . PHE B 1 69 ? 190.870 38.685 17.847 1.00 24.25 ? 67 PHE B CB 1 ATOM 3738 C CG . PHE B 1 69 ? 191.785 37.703 18.514 1.00 26.88 ? 67 PHE B CG 1 ATOM 3739 C CD1 . PHE B 1 69 ? 191.794 36.358 18.128 1.00 30.39 ? 67 PHE B CD1 1 ATOM 3740 C CD2 . PHE B 1 69 ? 192.617 38.104 19.561 1.00 29.17 ? 67 PHE B CD2 1 ATOM 3741 C CE1 . PHE B 1 69 ? 192.644 35.441 18.752 1.00 31.20 ? 67 PHE B CE1 1 ATOM 3742 C CE2 . PHE B 1 69 ? 193.471 37.188 20.184 1.00 31.51 ? 67 PHE B CE2 1 ATOM 3743 C CZ . PHE B 1 69 ? 193.481 35.863 19.772 1.00 30.12 ? 67 PHE B CZ 1 ATOM 3744 N N . ALA B 1 70 ? 189.625 39.640 20.517 1.00 28.27 ? 68 ALA B N 1 ATOM 3745 C CA . ALA B 1 70 ? 189.539 39.796 21.972 1.00 28.02 ? 68 ALA B CA 1 ATOM 3746 C C . ALA B 1 70 ? 188.109 39.627 22.497 1.00 31.21 ? 68 ALA B C 1 ATOM 3747 O O . ALA B 1 70 ? 187.928 38.875 23.448 1.00 30.97 ? 68 ALA B O 1 ATOM 3748 C CB . ALA B 1 70 ? 190.113 41.137 22.413 1.00 28.56 ? 68 ALA B CB 1 ATOM 3749 N N . LEU B 1 71 ? 187.099 40.292 21.882 1.00 26.90 ? 69 LEU B N 1 ATOM 3750 C CA . LEU B 1 71 ? 185.714 40.141 22.341 1.00 26.46 ? 69 LEU B CA 1 ATOM 3751 C C . LEU B 1 71 ? 185.286 38.695 22.202 1.00 32.12 ? 69 LEU B C 1 ATOM 3752 O O . LEU B 1 71 ? 184.864 38.133 23.215 1.00 32.09 ? 69 LEU B O 1 ATOM 3753 C CB . LEU B 1 71 ? 184.728 41.109 21.673 1.00 25.99 ? 69 LEU B CB 1 ATOM 3754 C CG . LEU B 1 71 ? 184.879 42.590 22.041 1.00 30.83 ? 69 LEU B CG 1 ATOM 3755 C CD1 . LEU B 1 71 ? 184.325 43.469 20.967 1.00 31.19 ? 69 LEU B CD1 1 ATOM 3756 C CD2 . LEU B 1 71 ? 184.186 42.932 23.354 1.00 33.03 ? 69 LEU B CD2 1 ATOM 3757 N N . ASP B 1 72 ? 185.520 38.051 21.002 1.00 28.73 ? 70 ASP B N 1 ATOM 3758 C CA . ASP B 1 72 ? 185.229 36.621 20.738 1.00 28.87 ? 70 ASP B CA 1 ATOM 3759 C C . ASP B 1 72 ? 185.762 35.707 21.877 1.00 33.82 ? 70 ASP B C 1 ATOM 3760 O O . ASP B 1 72 ? 184.972 34.971 22.448 1.00 35.27 ? 70 ASP B O 1 ATOM 3761 C CB . ASP B 1 72 ? 185.819 36.130 19.379 1.00 30.19 ? 70 ASP B CB 1 ATOM 3762 C CG . ASP B 1 72 ? 185.196 36.650 18.077 1.00 36.08 ? 70 ASP B CG 1 ATOM 3763 O OD1 . ASP B 1 72 ? 184.088 37.248 18.136 1.00 33.18 ? 70 ASP B OD1 1 ATOM 3764 O OD2 . ASP B 1 72 ? 185.829 36.464 16.995 1.00 41.37 ? 70 ASP B OD2 1 ATOM 3765 N N . ARG B 1 73 ? 187.079 35.786 22.212 1.00 28.68 ? 71 ARG B N 1 ATOM 3766 C CA . ARG B 1 73 ? 187.746 34.992 23.253 1.00 28.20 ? 71 ARG B CA 1 ATOM 3767 C C . ARG B 1 73 ? 187.101 35.111 24.605 1.00 33.88 ? 71 ARG B C 1 ATOM 3768 O O . ARG B 1 73 ? 186.893 34.093 25.278 1.00 36.98 ? 71 ARG B O 1 ATOM 3769 C CB . ARG B 1 73 ? 189.248 35.339 23.372 1.00 28.19 ? 71 ARG B CB 1 ATOM 3770 C CG . ARG B 1 73 ? 190.142 34.852 22.225 1.00 39.20 ? 71 ARG B CG 1 ATOM 3771 C CD . ARG B 1 73 ? 189.865 33.394 21.864 1.00 50.81 ? 71 ARG B CD 1 ATOM 3772 N NE . ARG B 1 73 ? 191.016 32.734 21.243 1.00 66.14 ? 71 ARG B NE 1 ATOM 3773 C CZ . ARG B 1 73 ? 191.961 32.080 21.916 1.00 67.33 ? 71 ARG B CZ 1 ATOM 3774 N NH1 . ARG B 1 73 ? 191.911 32.004 23.243 1.00 40.95 ? 71 ARG B NH1 1 ATOM 3775 N NH2 . ARG B 1 73 ? 192.964 31.501 21.269 1.00 47.02 ? 71 ARG B NH2 1 ATOM 3776 N N . ILE B 1 74 ? 186.784 36.349 25.000 1.00 27.47 ? 72 ILE B N 1 ATOM 3777 C CA . ILE B 1 74 ? 186.174 36.703 26.282 1.00 25.83 ? 72 ILE B CA 1 ATOM 3778 C C . ILE B 1 74 ? 184.779 36.110 26.334 1.00 32.95 ? 72 ILE B C 1 ATOM 3779 O O . ILE B 1 74 ? 184.322 35.720 27.410 1.00 33.58 ? 72 ILE B O 1 ATOM 3780 C CB . ILE B 1 74 ? 186.130 38.261 26.429 1.00 26.39 ? 72 ILE B CB 1 ATOM 3781 C CG1 . ILE B 1 74 ? 187.550 38.862 26.605 1.00 25.54 ? 72 ILE B CG1 1 ATOM 3782 C CG2 . ILE B 1 74 ? 185.148 38.725 27.524 1.00 23.26 ? 72 ILE B CG2 1 ATOM 3783 C CD1 . ILE B 1 74 ? 187.663 40.435 26.444 1.00 23.84 ? 72 ILE B CD1 1 ATOM 3784 N N . ASN B 1 75 ? 184.095 36.096 25.174 1.00 30.83 ? 73 ASN B N 1 ATOM 3785 C CA . ASN B 1 75 ? 182.715 35.636 25.009 1.00 31.22 ? 73 ASN B CA 1 ATOM 3786 C C . ASN B 1 75 ? 182.596 34.118 25.049 1.00 36.46 ? 73 ASN B C 1 ATOM 3787 O O . ASN B 1 75 ? 181.485 33.593 25.148 1.00 37.21 ? 73 ASN B O 1 ATOM 3788 C CB . ASN B 1 75 ? 182.093 36.235 23.749 1.00 31.19 ? 73 ASN B CB 1 ATOM 3789 C CG . ASN B 1 75 ? 181.636 37.663 23.901 1.00 43.83 ? 73 ASN B CG 1 ATOM 3790 O OD1 . ASN B 1 75 ? 181.207 38.127 24.965 1.00 37.75 ? 73 ASN B OD1 1 ATOM 3791 N ND2 . ASN B 1 75 ? 181.642 38.370 22.807 1.00 34.91 ? 73 ASN B ND2 1 ATOM 3792 N N . ARG B 1 76 ? 183.747 33.420 25.048 1.00 32.38 ? 74 ARG B N 1 ATOM 3793 C CA . ARG B 1 76 ? 183.801 31.971 25.173 1.00 32.54 ? 74 ARG B CA 1 ATOM 3794 C C . ARG B 1 76 ? 184.707 31.572 26.356 1.00 39.46 ? 74 ARG B C 1 ATOM 3795 O O . ARG B 1 76 ? 184.908 30.377 26.613 1.00 39.70 ? 74 ARG B O 1 ATOM 3796 C CB . ARG B 1 76 ? 184.174 31.286 23.848 1.00 31.87 ? 74 ARG B CB 1 ATOM 3797 C CG . ARG B 1 76 ? 185.604 31.517 23.346 1.00 38.94 ? 74 ARG B CG 1 ATOM 3798 C CD . ARG B 1 76 ? 185.826 30.690 22.105 1.00 41.35 ? 74 ARG B CD 1 ATOM 3799 N NE . ARG B 1 76 ? 187.203 30.695 21.611 1.00 52.46 ? 74 ARG B NE 1 ATOM 3800 C CZ . ARG B 1 76 ? 188.176 29.916 22.075 1.00 67.11 ? 74 ARG B CZ 1 ATOM 3801 N NH1 . ARG B 1 76 ? 187.955 29.105 23.104 1.00 61.92 ? 74 ARG B NH1 1 ATOM 3802 N NH2 . ARG B 1 76 ? 189.385 29.956 21.527 1.00 48.46 ? 74 ARG B NH2 1 ATOM 3803 N N . ASP B 1 77 ? 185.210 32.584 27.106 1.00 36.62 ? 75 ASP B N 1 ATOM 3804 C CA . ASP B 1 77 ? 186.030 32.374 28.305 1.00 36.45 ? 75 ASP B CA 1 ATOM 3805 C C . ASP B 1 77 ? 185.101 31.932 29.455 1.00 41.11 ? 75 ASP B C 1 ATOM 3806 O O . ASP B 1 77 ? 184.282 32.742 29.910 1.00 40.45 ? 75 ASP B O 1 ATOM 3807 C CB . ASP B 1 77 ? 186.815 33.657 28.710 1.00 37.63 ? 75 ASP B CB 1 ATOM 3808 C CG . ASP B 1 77 ? 187.915 33.435 29.744 1.00 45.50 ? 75 ASP B CG 1 ATOM 3809 O OD1 . ASP B 1 77 ? 187.700 32.626 30.697 1.00 46.89 ? 75 ASP B OD1 1 ATOM 3810 O OD2 . ASP B 1 77 ? 188.997 34.043 29.598 1.00 46.18 ? 75 ASP B OD2 1 ATOM 3811 N N . PRO B 1 78 ? 185.226 30.677 29.967 1.00 38.27 ? 76 PRO B N 1 ATOM 3812 C CA . PRO B 1 78 ? 184.353 30.260 31.086 1.00 37.79 ? 76 PRO B CA 1 ATOM 3813 C C . PRO B 1 78 ? 184.580 31.000 32.411 1.00 43.36 ? 76 PRO B C 1 ATOM 3814 O O . PRO B 1 78 ? 183.684 30.963 33.246 1.00 44.36 ? 76 PRO B O 1 ATOM 3815 C CB . PRO B 1 78 ? 184.598 28.747 31.211 1.00 38.68 ? 76 PRO B CB 1 ATOM 3816 C CG . PRO B 1 78 ? 185.892 28.493 30.578 1.00 42.74 ? 76 PRO B CG 1 ATOM 3817 C CD . PRO B 1 78 ? 186.136 29.582 29.553 1.00 39.30 ? 76 PRO B CD 1 ATOM 3818 N N . HIS B 1 79 ? 185.722 31.702 32.585 1.00 40.64 ? 77 HIS B N 1 ATOM 3819 C CA . HIS B 1 79 ? 186.079 32.412 33.826 1.00 41.51 ? 77 HIS B CA 1 ATOM 3820 C C . HIS B 1 79 ? 186.043 33.942 33.737 1.00 43.48 ? 77 HIS B C 1 ATOM 3821 O O . HIS B 1 79 ? 186.619 34.625 34.595 1.00 44.28 ? 77 HIS B O 1 ATOM 3822 C CB . HIS B 1 79 ? 187.465 31.936 34.295 1.00 43.91 ? 77 HIS B CB 1 ATOM 3823 C CG . HIS B 1 79 ? 187.549 30.445 34.391 1.00 49.02 ? 77 HIS B CG 1 ATOM 3824 N ND1 . HIS B 1 79 ? 188.026 29.682 33.337 1.00 51.46 ? 77 HIS B ND1 1 ATOM 3825 C CD2 . HIS B 1 79 ? 187.096 29.617 35.363 1.00 51.74 ? 77 HIS B CD2 1 ATOM 3826 C CE1 . HIS B 1 79 ? 187.894 28.424 33.720 1.00 51.38 ? 77 HIS B CE1 1 ATOM 3827 N NE2 . HIS B 1 79 ? 187.335 28.336 34.930 1.00 51.87 ? 77 HIS B NE2 1 ATOM 3828 N N . LEU B 1 80 ? 185.391 34.486 32.696 1.00 36.39 ? 78 LEU B N 1 ATOM 3829 C CA . LEU B 1 80 ? 185.333 35.925 32.477 1.00 34.12 ? 78 LEU B CA 1 ATOM 3830 C C . LEU B 1 80 ? 184.012 36.261 31.813 1.00 36.85 ? 78 LEU B C 1 ATOM 3831 O O . LEU B 1 80 ? 183.798 35.917 30.647 1.00 36.54 ? 78 LEU B O 1 ATOM 3832 C CB . LEU B 1 80 ? 186.553 36.400 31.652 1.00 33.18 ? 78 LEU B CB 1 ATOM 3833 C CG . LEU B 1 80 ? 186.788 37.907 31.561 1.00 35.85 ? 78 LEU B CG 1 ATOM 3834 C CD1 . LEU B 1 80 ? 187.004 38.557 32.958 1.00 36.53 ? 78 LEU B CD1 1 ATOM 3835 C CD2 . LEU B 1 80 ? 187.918 38.205 30.645 1.00 31.71 ? 78 LEU B CD2 1 ATOM 3836 N N . LEU B 1 81 ? 183.105 36.896 32.603 1.00 32.11 ? 79 LEU B N 1 ATOM 3837 C CA . LEU B 1 81 ? 181.729 37.254 32.262 1.00 30.88 ? 79 LEU B CA 1 ATOM 3838 C C . LEU B 1 81 ? 181.059 36.060 31.583 1.00 37.05 ? 79 LEU B C 1 ATOM 3839 O O . LEU B 1 81 ? 180.645 36.176 30.429 1.00 35.80 ? 79 LEU B O 1 ATOM 3840 C CB . LEU B 1 81 ? 181.654 38.500 31.374 1.00 30.09 ? 79 LEU B CB 1 ATOM 3841 C CG . LEU B 1 81 ? 182.106 39.801 31.968 1.00 32.54 ? 79 LEU B CG 1 ATOM 3842 C CD1 . LEU B 1 81 ? 182.162 40.850 30.906 1.00 31.29 ? 79 LEU B CD1 1 ATOM 3843 C CD2 . LEU B 1 81 ? 181.205 40.215 33.114 1.00 34.14 ? 79 LEU B CD2 1 ATOM 3844 N N . PRO B 1 82 ? 181.013 34.876 32.255 1.00 36.40 ? 80 PRO B N 1 ATOM 3845 C CA . PRO B 1 82 ? 180.420 33.689 31.607 1.00 36.42 ? 80 PRO B CA 1 ATOM 3846 C C . PRO B 1 82 ? 178.932 33.798 31.283 1.00 41.03 ? 80 PRO B C 1 ATOM 3847 O O . PRO B 1 82 ? 178.472 33.062 30.417 1.00 44.39 ? 80 PRO B O 1 ATOM 3848 C CB . PRO B 1 82 ? 180.713 32.559 32.601 1.00 37.92 ? 80 PRO B CB 1 ATOM 3849 C CG . PRO B 1 82 ? 180.835 33.250 33.925 1.00 41.66 ? 80 PRO B CG 1 ATOM 3850 C CD . PRO B 1 82 ? 181.502 34.551 33.619 1.00 37.07 ? 80 PRO B CD 1 ATOM 3851 N N . GLY B 1 83 ? 178.212 34.714 31.924 1.00 35.15 ? 81 GLY B N 1 ATOM 3852 C CA . GLY B 1 83 ? 176.783 34.904 31.687 1.00 34.53 ? 81 GLY B CA 1 ATOM 3853 C C . GLY B 1 83 ? 176.400 36.240 31.094 1.00 39.62 ? 81 GLY B C 1 ATOM 3854 O O . GLY B 1 83 ? 175.219 36.484 30.843 1.00 40.07 ? 81 GLY B O 1 ATOM 3855 N N . VAL B 1 84 ? 177.386 37.133 30.887 1.00 36.33 ? 82 VAL B N 1 ATOM 3856 C CA . VAL B 1 84 ? 177.162 38.448 30.264 1.00 35.21 ? 82 VAL B CA 1 ATOM 3857 C C . VAL B 1 84 ? 177.969 38.512 28.954 1.00 37.79 ? 82 VAL B C 1 ATOM 3858 O O . VAL B 1 84 ? 179.196 38.483 29.008 1.00 37.86 ? 82 VAL B O 1 ATOM 3859 C CB . VAL B 1 84 ? 177.512 39.626 31.208 1.00 38.39 ? 82 VAL B CB 1 ATOM 3860 C CG1 . VAL B 1 84 ? 177.373 40.959 30.485 1.00 38.13 ? 82 VAL B CG1 1 ATOM 3861 C CG2 . VAL B 1 84 ? 176.661 39.606 32.477 1.00 37.96 ? 82 VAL B CG2 1 ATOM 3862 N N . ARG B 1 85 ? 177.291 38.555 27.789 1.00 33.56 ? 83 ARG B N 1 ATOM 3863 C CA . ARG B 1 85 ? 177.967 38.656 26.490 1.00 33.41 ? 83 ARG B CA 1 ATOM 3864 C C . ARG B 1 85 ? 178.360 40.105 26.171 1.00 36.24 ? 83 ARG B C 1 ATOM 3865 O O . ARG B 1 85 ? 177.563 41.041 26.314 1.00 33.22 ? 83 ARG B O 1 ATOM 3866 C CB . ARG B 1 85 ? 177.127 38.038 25.365 1.00 33.76 ? 83 ARG B CB 1 ATOM 3867 C CG . ARG B 1 85 ? 177.653 38.274 23.948 1.00 40.82 ? 83 ARG B CG 1 ATOM 3868 C CD . ARG B 1 85 ? 176.963 37.393 22.919 1.00 46.86 ? 83 ARG B CD 1 ATOM 3869 N NE . ARG B 1 85 ? 177.903 36.448 22.315 1.00 58.64 ? 83 ARG B NE 1 ATOM 3870 C CZ . ARG B 1 85 ? 178.594 36.678 21.201 1.00 83.14 ? 83 ARG B CZ 1 ATOM 3871 N NH1 . ARG B 1 85 ? 178.443 37.822 20.539 1.00 85.01 ? 83 ARG B NH1 1 ATOM 3872 N NH2 . ARG B 1 85 ? 179.436 35.765 20.736 1.00 62.91 ? 83 ARG B NH2 1 ATOM 3873 N N . LEU B 1 86 ? 179.613 40.276 25.760 1.00 34.96 ? 84 LEU B N 1 ATOM 3874 C CA . LEU B 1 86 ? 180.138 41.587 25.389 1.00 34.23 ? 84 LEU B CA 1 ATOM 3875 C C . LEU B 1 86 ? 179.981 41.814 23.903 1.00 34.77 ? 84 LEU B C 1 ATOM 3876 O O . LEU B 1 86 ? 180.561 41.067 23.116 1.00 33.89 ? 84 LEU B O 1 ATOM 3877 C CB . LEU B 1 86 ? 181.624 41.715 25.781 1.00 34.02 ? 84 LEU B CB 1 ATOM 3878 C CG . LEU B 1 86 ? 181.957 41.923 27.248 1.00 37.70 ? 84 LEU B CG 1 ATOM 3879 C CD1 . LEU B 1 86 ? 183.395 42.407 27.398 1.00 36.71 ? 84 LEU B CD1 1 ATOM 3880 C CD2 . LEU B 1 86 ? 180.993 42.916 27.908 1.00 40.08 ? 84 LEU B CD2 1 ATOM 3881 N N . GLY B 1 87 ? 179.166 42.804 23.549 1.00 29.88 ? 85 GLY B N 1 ATOM 3882 C CA . GLY B 1 87 ? 178.933 43.246 22.174 1.00 29.44 ? 85 GLY B CA 1 ATOM 3883 C C . GLY B 1 87 ? 179.807 44.445 21.834 1.00 31.63 ? 85 GLY B C 1 ATOM 3884 O O . GLY B 1 87 ? 180.615 44.873 22.662 1.00 31.84 ? 85 GLY B O 1 ATOM 3885 N N . ALA B 1 88 ? 179.682 44.993 20.622 1.00 26.85 ? 86 ALA B N 1 ATOM 3886 C CA . ALA B 1 88 ? 180.519 46.126 20.185 1.00 26.34 ? 86 ALA B CA 1 ATOM 3887 C C . ALA B 1 88 ? 179.802 47.166 19.356 1.00 33.07 ? 86 ALA B C 1 ATOM 3888 O O . ALA B 1 88 ? 178.760 46.894 18.744 1.00 34.52 ? 86 ALA B O 1 ATOM 3889 C CB . ALA B 1 88 ? 181.737 45.632 19.417 1.00 26.69 ? 86 ALA B CB 1 ATOM 3890 N N . HIS B 1 89 ? 180.381 48.370 19.325 1.00 28.25 ? 87 HIS B N 1 ATOM 3891 C CA . HIS B 1 89 ? 179.902 49.488 18.542 1.00 26.66 ? 87 HIS B CA 1 ATOM 3892 C C . HIS B 1 89 ? 181.156 50.264 18.223 1.00 27.98 ? 87 HIS B C 1 ATOM 3893 O O . HIS B 1 89 ? 181.567 51.181 18.945 1.00 27.72 ? 87 HIS B O 1 ATOM 3894 C CB . HIS B 1 89 ? 178.864 50.274 19.316 1.00 28.39 ? 87 HIS B CB 1 ATOM 3895 C CG . HIS B 1 89 ? 178.179 51.304 18.503 1.00 33.15 ? 87 HIS B CG 1 ATOM 3896 N ND1 . HIS B 1 89 ? 178.585 52.617 18.527 1.00 35.53 ? 87 HIS B ND1 1 ATOM 3897 C CD2 . HIS B 1 89 ? 177.141 51.182 17.650 1.00 36.48 ? 87 HIS B CD2 1 ATOM 3898 C CE1 . HIS B 1 89 ? 177.787 53.260 17.695 1.00 35.37 ? 87 HIS B CE1 1 ATOM 3899 N NE2 . HIS B 1 89 ? 176.898 52.444 17.149 1.00 36.20 ? 87 HIS B NE2 1 ATOM 3900 N N . ILE B 1 90 ? 181.826 49.806 17.156 1.00 23.67 ? 88 ILE B N 1 ATOM 3901 C CA . ILE B 1 90 ? 183.107 50.331 16.711 1.00 22.19 ? 88 ILE B CA 1 ATOM 3902 C C . ILE B 1 90 ? 182.973 51.389 15.586 1.00 27.04 ? 88 ILE B C 1 ATOM 3903 O O . ILE B 1 90 ? 182.209 51.236 14.632 1.00 27.25 ? 88 ILE B O 1 ATOM 3904 C CB . ILE B 1 90 ? 184.071 49.191 16.363 1.00 23.45 ? 88 ILE B CB 1 ATOM 3905 C CG1 . ILE B 1 90 ? 184.299 48.296 17.599 1.00 22.79 ? 88 ILE B CG1 1 ATOM 3906 C CG2 . ILE B 1 90 ? 185.374 49.762 15.860 1.00 23.73 ? 88 ILE B CG2 1 ATOM 3907 C CD1 . ILE B 1 90 ? 184.760 46.830 17.291 1.00 26.35 ? 88 ILE B CD1 1 ATOM 3908 N N . LEU B 1 91 ? 183.772 52.457 15.738 1.00 21.82 ? 89 LEU B N 1 ATOM 3909 C CA . LEU B 1 91 ? 183.800 53.627 14.907 1.00 20.16 ? 89 LEU B CA 1 ATOM 3910 C C . LEU B 1 91 ? 185.173 53.927 14.336 1.00 23.23 ? 89 LEU B C 1 ATOM 3911 O O . LEU B 1 91 ? 186.190 53.540 14.892 1.00 22.09 ? 89 LEU B O 1 ATOM 3912 C CB . LEU B 1 91 ? 183.267 54.807 15.709 1.00 20.07 ? 89 LEU B CB 1 ATOM 3913 C CG . LEU B 1 91 ? 181.857 54.636 16.257 1.00 24.86 ? 89 LEU B CG 1 ATOM 3914 C CD1 . LEU B 1 91 ? 181.462 55.818 17.114 1.00 24.91 ? 89 LEU B CD1 1 ATOM 3915 C CD2 . LEU B 1 91 ? 180.868 54.451 15.140 1.00 25.56 ? 89 LEU B CD2 1 ATOM 3916 N N . ASP B 1 92 ? 185.175 54.570 13.167 1.00 19.82 ? 90 ASP B N 1 ATOM 3917 C CA . ASP B 1 92 ? 186.363 54.931 12.453 1.00 19.73 ? 90 ASP B CA 1 ATOM 3918 C C . ASP B 1 92 ? 186.627 56.413 12.716 1.00 25.58 ? 90 ASP B C 1 ATOM 3919 O O . ASP B 1 92 ? 185.757 57.264 12.511 1.00 25.47 ? 90 ASP B O 1 ATOM 3920 C CB . ASP B 1 92 ? 186.190 54.607 10.963 1.00 21.21 ? 90 ASP B CB 1 ATOM 3921 C CG . ASP B 1 92 ? 187.313 55.070 10.055 1.00 27.22 ? 90 ASP B CG 1 ATOM 3922 O OD1 . ASP B 1 92 ? 188.462 55.201 10.534 1.00 25.00 ? 90 ASP B OD1 1 ATOM 3923 O OD2 . ASP B 1 92 ? 187.051 55.284 8.878 1.00 35.97 ? 90 ASP B OD2 1 ATOM 3924 N N . SER B 1 93 ? 187.816 56.704 13.227 1.00 23.02 ? 91 SER B N 1 ATOM 3925 C CA . SER B 1 93 ? 188.203 58.059 13.584 1.00 23.21 ? 91 SER B CA 1 ATOM 3926 C C . SER B 1 93 ? 188.658 58.849 12.355 1.00 31.19 ? 91 SER B C 1 ATOM 3927 O O . SER B 1 93 ? 188.665 60.076 12.411 1.00 29.99 ? 91 SER B O 1 ATOM 3928 C CB . SER B 1 93 ? 189.325 58.009 14.611 1.00 22.91 ? 91 SER B CB 1 ATOM 3929 O OG . SER B 1 93 ? 190.496 57.492 13.999 1.00 23.30 ? 91 SER B OG 1 ATOM 3930 N N . CYS B 1 94 ? 189.073 58.132 11.273 1.00 31.21 ? 92 CYS B N 1 ATOM 3931 C CA . CYS B 1 94 ? 189.645 58.642 10.029 1.00 33.59 ? 92 CYS B CA 1 ATOM 3932 C C . CYS B 1 94 ? 190.912 59.414 10.283 1.00 32.48 ? 92 CYS B C 1 ATOM 3933 O O . CYS B 1 94 ? 191.227 60.339 9.549 1.00 30.74 ? 92 CYS B O 1 ATOM 3934 C CB . CYS B 1 94 ? 188.644 59.424 9.185 1.00 37.84 ? 92 CYS B CB 1 ATOM 3935 S SG . CYS B 1 94 ? 187.377 58.387 8.427 1.00 45.03 ? 92 CYS B SG 1 ATOM 3936 N N . SER B 1 95 ? 191.660 59.009 11.329 1.00 28.28 ? 93 SER B N 1 ATOM 3937 C CA . SER B 1 95 ? 192.955 59.578 11.767 1.00 27.90 ? 93 SER B CA 1 ATOM 3938 C C . SER B 1 95 ? 192.880 61.110 12.024 1.00 30.85 ? 93 SER B C 1 ATOM 3939 O O . SER B 1 95 ? 193.898 61.837 11.951 1.00 29.74 ? 93 SER B O 1 ATOM 3940 C CB . SER B 1 95 ? 194.069 59.204 10.782 1.00 28.60 ? 93 SER B CB 1 ATOM 3941 O OG . SER B 1 95 ? 194.166 57.799 10.590 1.00 31.17 ? 93 SER B OG 1 ATOM 3942 N N . LYS B 1 96 ? 191.651 61.571 12.376 1.00 25.10 ? 94 LYS B N 1 ATOM 3943 C CA . LYS B 1 96 ? 191.303 62.982 12.506 1.00 23.90 ? 94 LYS B CA 1 ATOM 3944 C C . LYS B 1 96 ? 190.325 63.213 13.659 1.00 28.18 ? 94 LYS B C 1 ATOM 3945 O O . LYS B 1 96 ? 189.232 62.643 13.649 1.00 29.15 ? 94 LYS B O 1 ATOM 3946 C CB . LYS B 1 96 ? 190.715 63.414 11.152 1.00 23.96 ? 94 LYS B CB 1 ATOM 3947 C CG . LYS B 1 96 ? 190.285 64.824 10.989 1.00 30.27 ? 94 LYS B CG 1 ATOM 3948 C CD . LYS B 1 96 ? 189.931 64.976 9.512 1.00 50.59 ? 94 LYS B CD 1 ATOM 3949 C CE . LYS B 1 96 ? 189.329 66.315 9.170 1.00 72.03 ? 94 LYS B CE 1 ATOM 3950 N NZ . LYS B 1 96 ? 188.792 66.338 7.785 1.00 85.05 ? 94 LYS B NZ 1 ATOM 3951 N N . ASP B 1 97 ? 190.722 64.039 14.653 1.00 23.46 ? 95 ASP B N 1 ATOM 3952 C CA . ASP B 1 97 ? 189.888 64.357 15.831 1.00 22.98 ? 95 ASP B CA 1 ATOM 3953 C C . ASP B 1 97 ? 188.500 64.951 15.518 1.00 25.20 ? 95 ASP B C 1 ATOM 3954 O O . ASP B 1 97 ? 187.571 64.612 16.224 1.00 25.98 ? 95 ASP B O 1 ATOM 3955 C CB . ASP B 1 97 ? 190.621 65.265 16.834 1.00 25.14 ? 95 ASP B CB 1 ATOM 3956 C CG . ASP B 1 97 ? 191.319 66.517 16.281 1.00 45.43 ? 95 ASP B CG 1 ATOM 3957 O OD1 . ASP B 1 97 ? 190.966 66.961 15.128 1.00 45.79 ? 95 ASP B OD1 1 ATOM 3958 O OD2 . ASP B 1 97 ? 192.238 67.044 16.981 1.00 51.82 ? 95 ASP B OD2 1 ATOM 3959 N N . THR B 1 98 ? 188.352 65.809 14.496 1.00 19.83 ? 96 THR B N 1 ATOM 3960 C CA . THR B 1 98 ? 187.053 66.397 14.178 1.00 19.79 ? 96 THR B CA 1 ATOM 3961 C C . THR B 1 98 ? 186.056 65.346 13.763 1.00 24.45 ? 96 THR B C 1 ATOM 3962 O O . THR B 1 98 ? 184.919 65.357 14.266 1.00 22.88 ? 96 THR B O 1 ATOM 3963 C CB . THR B 1 98 ? 187.143 67.555 13.159 1.00 30.26 ? 96 THR B CB 1 ATOM 3964 O OG1 . THR B 1 98 ? 187.887 67.139 12.033 1.00 38.36 ? 96 THR B OG1 1 ATOM 3965 C CG2 . THR B 1 98 ? 187.790 68.795 13.729 1.00 26.37 ? 96 THR B CG2 1 ATOM 3966 N N . HIS B 1 99 ? 186.509 64.393 12.889 1.00 21.78 ? 97 HIS B N 1 ATOM 3967 C CA . HIS B 1 99 ? 185.739 63.265 12.372 1.00 20.40 ? 97 HIS B CA 1 ATOM 3968 C C . HIS B 1 99 ? 185.396 62.358 13.544 1.00 25.71 ? 97 HIS B C 1 ATOM 3969 O O . HIS B 1 99 ? 184.236 61.998 13.725 1.00 26.27 ? 97 HIS B O 1 ATOM 3970 C CB . HIS B 1 99 ? 186.536 62.464 11.307 1.00 20.93 ? 97 HIS B CB 1 ATOM 3971 C CG . HIS B 1 99 ? 185.720 61.322 10.747 1.00 25.04 ? 97 HIS B CG 1 ATOM 3972 N ND1 . HIS B 1 99 ? 185.007 61.449 9.552 1.00 26.46 ? 97 HIS B ND1 1 ATOM 3973 C CD2 . HIS B 1 99 ? 185.410 60.121 11.310 1.00 27.54 ? 97 HIS B CD2 1 ATOM 3974 C CE1 . HIS B 1 99 ? 184.312 60.331 9.424 1.00 26.42 ? 97 HIS B CE1 1 ATOM 3975 N NE2 . HIS B 1 99 ? 184.524 59.496 10.452 1.00 27.48 ? 97 HIS B NE2 1 ATOM 3976 N N . ALA B 1 100 ? 186.407 61.986 14.340 1.00 22.39 ? 98 ALA B N 1 ATOM 3977 C CA . ALA B 1 100 ? 186.242 61.099 15.490 1.00 23.07 ? 98 ALA B CA 1 ATOM 3978 C C . ALA B 1 100 ? 185.201 61.600 16.453 1.00 29.55 ? 98 ALA B C 1 ATOM 3979 O O . ALA B 1 100 ? 184.437 60.802 17.003 1.00 30.57 ? 98 ALA B O 1 ATOM 3980 C CB . ALA B 1 100 ? 187.573 60.908 16.213 1.00 23.91 ? 98 ALA B CB 1 ATOM 3981 N N . LEU B 1 101 ? 185.165 62.913 16.668 1.00 26.85 ? 99 LEU B N 1 ATOM 3982 C CA . LEU B 1 101 ? 184.210 63.499 17.587 1.00 27.75 ? 99 LEU B CA 1 ATOM 3983 C C . LEU B 1 101 ? 182.784 63.425 17.050 1.00 32.21 ? 99 LEU B C 1 ATOM 3984 O O . LEU B 1 101 ? 181.871 63.089 17.806 1.00 30.60 ? 99 LEU B O 1 ATOM 3985 C CB . LEU B 1 101 ? 184.632 64.908 17.979 1.00 28.53 ? 99 LEU B CB 1 ATOM 3986 C CG . LEU B 1 101 ? 184.133 65.353 19.343 1.00 35.26 ? 99 LEU B CG 1 ATOM 3987 C CD1 . LEU B 1 101 ? 184.705 64.481 20.466 1.00 36.12 ? 99 LEU B CD1 1 ATOM 3988 C CD2 . LEU B 1 101 ? 184.395 66.820 19.558 1.00 37.99 ? 99 LEU B CD2 1 ATOM 3989 N N . GLU B 1 102 ? 182.604 63.676 15.730 1.00 30.12 ? 100 GLU B N 1 ATOM 3990 C CA . GLU B 1 102 ? 181.314 63.565 15.050 1.00 29.84 ? 100 GLU B CA 1 ATOM 3991 C C . GLU B 1 102 ? 180.795 62.109 15.266 1.00 33.25 ? 100 GLU B C 1 ATOM 3992 O O . GLU B 1 102 ? 179.620 61.906 15.590 1.00 34.03 ? 100 GLU B O 1 ATOM 3993 C CB . GLU B 1 102 ? 181.484 63.820 13.548 1.00 31.57 ? 100 GLU B CB 1 ATOM 3994 C CG . GLU B 1 102 ? 181.921 65.221 13.127 1.00 45.71 ? 100 GLU B CG 1 ATOM 3995 C CD . GLU B 1 102 ? 182.556 65.350 11.743 1.00 68.97 ? 100 GLU B CD 1 ATOM 3996 O OE1 . GLU B 1 102 ? 182.457 64.393 10.937 1.00 60.56 ? 100 GLU B OE1 1 ATOM 3997 O OE2 . GLU B 1 102 ? 183.166 66.412 11.467 1.00 57.36 ? 100 GLU B OE2 1 ATOM 3998 N N . GLN B 1 103 ? 181.702 61.111 15.148 1.00 26.59 ? 101 GLN B N 1 ATOM 3999 C CA . GLN B 1 103 ? 181.386 59.698 15.343 1.00 24.35 ? 101 GLN B CA 1 ATOM 4000 C C . GLN B 1 103 ? 181.130 59.373 16.795 1.00 29.01 ? 101 GLN B C 1 ATOM 4001 O O . GLN B 1 103 ? 180.133 58.715 17.072 1.00 29.57 ? 101 GLN B O 1 ATOM 4002 C CB . GLN B 1 103 ? 182.470 58.790 14.766 1.00 24.36 ? 101 GLN B CB 1 ATOM 4003 C CG . GLN B 1 103 ? 182.590 58.877 13.256 1.00 23.00 ? 101 GLN B CG 1 ATOM 4004 C CD . GLN B 1 103 ? 181.319 58.496 12.555 1.00 33.12 ? 101 GLN B CD 1 ATOM 4005 O OE1 . GLN B 1 103 ? 180.812 57.374 12.653 1.00 31.34 ? 101 GLN B OE1 1 ATOM 4006 N NE2 . GLN B 1 103 ? 180.775 59.432 11.829 1.00 26.20 ? 101 GLN B NE2 1 ATOM 4007 N N . ALA B 1 104 ? 181.989 59.865 17.728 1.00 24.38 ? 102 ALA B N 1 ATOM 4008 C CA . ALA B 1 104 ? 181.848 59.665 19.164 1.00 24.37 ? 102 ALA B CA 1 ATOM 4009 C C . ALA B 1 104 ? 180.498 60.145 19.767 1.00 30.07 ? 102 ALA B C 1 ATOM 4010 O O . ALA B 1 104 ? 180.146 59.698 20.842 1.00 30.50 ? 102 ALA B O 1 ATOM 4011 C CB . ALA B 1 104 ? 183.016 60.293 19.892 1.00 25.53 ? 102 ALA B CB 1 ATOM 4012 N N . LEU B 1 105 ? 179.722 60.997 19.071 1.00 29.56 ? 103 LEU B N 1 ATOM 4013 C CA . LEU B 1 105 ? 178.377 61.390 19.502 1.00 30.98 ? 103 LEU B CA 1 ATOM 4014 C C . LEU B 1 105 ? 177.483 60.148 19.621 1.00 36.77 ? 103 LEU B C 1 ATOM 4015 O O . LEU B 1 105 ? 176.619 60.113 20.497 1.00 37.90 ? 103 LEU B O 1 ATOM 4016 C CB . LEU B 1 105 ? 177.724 62.372 18.527 1.00 31.45 ? 103 LEU B CB 1 ATOM 4017 C CG . LEU B 1 105 ? 178.067 63.843 18.692 1.00 36.77 ? 103 LEU B CG 1 ATOM 4018 C CD1 . LEU B 1 105 ? 177.292 64.684 17.705 1.00 36.42 ? 103 LEU B CD1 1 ATOM 4019 C CD2 . LEU B 1 105 ? 177.788 64.331 20.102 1.00 40.38 ? 103 LEU B CD2 1 ATOM 4020 N N . ASP B 1 106 ? 177.716 59.119 18.767 1.00 32.07 ? 104 ASP B N 1 ATOM 4021 C CA . ASP B 1 106 ? 177.032 57.831 18.839 1.00 32.20 ? 104 ASP B CA 1 ATOM 4022 C C . ASP B 1 106 ? 177.156 57.235 20.232 1.00 37.69 ? 104 ASP B C 1 ATOM 4023 O O . ASP B 1 106 ? 176.202 56.628 20.708 1.00 40.12 ? 104 ASP B O 1 ATOM 4024 C CB . ASP B 1 106 ? 177.668 56.829 17.884 1.00 34.71 ? 104 ASP B CB 1 ATOM 4025 C CG . ASP B 1 106 ? 177.258 56.923 16.435 1.00 49.46 ? 104 ASP B CG 1 ATOM 4026 O OD1 . ASP B 1 106 ? 176.885 58.028 15.995 1.00 50.48 ? 104 ASP B OD1 1 ATOM 4027 O OD2 . ASP B 1 106 ? 177.340 55.888 15.729 1.00 58.36 ? 104 ASP B OD2 1 ATOM 4028 N N . PHE B 1 107 ? 178.315 57.401 20.896 1.00 32.41 ? 105 PHE B N 1 ATOM 4029 C CA . PHE B 1 107 ? 178.521 56.845 22.236 1.00 30.72 ? 105 PHE B CA 1 ATOM 4030 C C . PHE B 1 107 ? 177.717 57.528 23.307 1.00 39.80 ? 105 PHE B C 1 ATOM 4031 O O . PHE B 1 107 ? 177.367 56.898 24.293 1.00 40.77 ? 105 PHE B O 1 ATOM 4032 C CB . PHE B 1 107 ? 180.004 56.876 22.608 1.00 30.22 ? 105 PHE B CB 1 ATOM 4033 C CG . PHE B 1 107 ? 180.911 56.085 21.701 1.00 30.24 ? 105 PHE B CG 1 ATOM 4034 C CD1 . PHE B 1 107 ? 180.484 54.893 21.126 1.00 32.14 ? 105 PHE B CD1 1 ATOM 4035 C CD2 . PHE B 1 107 ? 182.203 56.518 21.434 1.00 30.57 ? 105 PHE B CD2 1 ATOM 4036 C CE1 . PHE B 1 107 ? 181.333 54.159 20.297 1.00 32.43 ? 105 PHE B CE1 1 ATOM 4037 C CE2 . PHE B 1 107 ? 183.049 55.778 20.612 1.00 32.03 ? 105 PHE B CE2 1 ATOM 4038 C CZ . PHE B 1 107 ? 182.618 54.590 20.072 1.00 30.17 ? 105 PHE B CZ 1 ATOM 4039 N N . VAL B 1 108 ? 177.448 58.828 23.132 1.00 40.06 ? 106 VAL B N 1 ATOM 4040 C CA . VAL B 1 108 ? 176.794 59.675 24.135 1.00 40.33 ? 106 VAL B CA 1 ATOM 4041 C C . VAL B 1 108 ? 175.316 59.953 23.850 1.00 49.19 ? 106 VAL B C 1 ATOM 4042 O O . VAL B 1 108 ? 174.666 60.592 24.678 1.00 50.29 ? 106 VAL B O 1 ATOM 4043 C CB . VAL B 1 108 ? 177.590 61.004 24.360 1.00 41.99 ? 106 VAL B CB 1 ATOM 4044 C CG1 . VAL B 1 108 ? 179.091 60.746 24.501 1.00 40.47 ? 106 VAL B CG1 1 ATOM 4045 C CG2 . VAL B 1 108 ? 177.315 62.025 23.259 1.00 41.47 ? 106 VAL B CG2 1 ATOM 4046 N N . ARG B 1 109 ? 174.789 59.502 22.701 1.00 48.70 ? 107 ARG B N 1 ATOM 4047 C CA . ARG B 1 109 ? 173.400 59.770 22.325 1.00 50.45 ? 107 ARG B CA 1 ATOM 4048 C C . ARG B 1 109 ? 172.341 59.018 23.163 1.00 60.58 ? 107 ARG B C 1 ATOM 4049 O O . ARG B 1 109 ? 171.151 59.295 22.992 1.00 62.13 ? 107 ARG B O 1 ATOM 4050 C CB . ARG B 1 109 ? 173.167 59.556 20.828 1.00 49.06 ? 107 ARG B CB 1 ATOM 4051 C CG . ARG B 1 109 ? 173.374 60.836 20.045 1.00 48.76 ? 107 ARG B CG 1 ATOM 4052 C CD . ARG B 1 109 ? 172.601 60.858 18.752 1.00 53.16 ? 107 ARG B CD 1 ATOM 4053 N NE . ARG B 1 109 ? 173.317 61.627 17.738 1.00 64.11 ? 107 ARG B NE 1 ATOM 4054 C CZ . ARG B 1 109 ? 174.187 61.099 16.880 1.00 73.94 ? 107 ARG B CZ 1 ATOM 4055 N NH1 . ARG B 1 109 ? 174.812 61.872 16.000 1.00 63.45 ? 107 ARG B NH1 1 ATOM 4056 N NH2 . ARG B 1 109 ? 174.439 59.793 16.896 1.00 45.85 ? 107 ARG B NH2 1 ATOM 4057 N N . ALA B 1 110 ? 172.751 58.144 24.109 1.00 59.06 ? 108 ALA B N 1 ATOM 4058 C CA . ALA B 1 110 ? 171.819 57.442 25.003 1.00 59.74 ? 108 ALA B CA 1 ATOM 4059 C C . ALA B 1 110 ? 171.241 58.402 26.081 1.00 65.82 ? 108 ALA B C 1 ATOM 4060 O O . ALA B 1 110 ? 170.329 58.017 26.821 1.00 66.81 ? 108 ALA B O 1 ATOM 4061 C CB . ALA B 1 110 ? 172.519 56.261 25.668 1.00 60.44 ? 108 ALA B CB 1 ATOM 4062 N N . SER B 1 111 ? 171.777 59.647 26.157 1.00 62.08 ? 109 SER B N 1 ATOM 4063 C CA . SER B 1 111 ? 171.410 60.701 27.111 1.00 79.13 ? 109 SER B CA 1 ATOM 4064 C C . SER B 1 111 ? 171.728 62.067 26.525 1.00 96.89 ? 109 SER B C 1 ATOM 4065 O O . SER B 1 111 ? 170.867 62.692 25.919 1.00 68.22 ? 109 SER B O 1 ATOM 4066 C CB . SER B 1 111 ? 172.184 60.527 28.414 1.00 82.49 ? 109 SER B CB 1 ATOM 4067 O OG . SER B 1 111 ? 173.579 60.445 28.164 1.00 91.03 ? 109 SER B OG 1 ATOM 4068 N N . THR B 1 136 ? 171.016 52.719 22.108 1.00 66.91 ? 134 THR B N 1 ATOM 4069 C CA . THR B 1 136 ? 171.711 51.626 22.808 1.00 67.04 ? 134 THR B CA 1 ATOM 4070 C C . THR B 1 136 ? 172.809 52.144 23.753 1.00 70.19 ? 134 THR B C 1 ATOM 4071 O O . THR B 1 136 ? 173.569 53.067 23.402 1.00 71.42 ? 134 THR B O 1 ATOM 4072 C CB . THR B 1 136 ? 172.284 50.586 21.827 1.00 76.74 ? 134 THR B CB 1 ATOM 4073 O OG1 . THR B 1 136 ? 173.136 51.223 20.863 1.00 79.08 ? 134 THR B OG1 1 ATOM 4074 C CG2 . THR B 1 136 ? 171.208 49.726 21.172 1.00 71.32 ? 134 THR B CG2 1 ATOM 4075 N N . ALA B 1 137 ? 172.897 51.538 24.951 1.00 62.40 ? 135 ALA B N 1 ATOM 4076 C CA . ALA B 1 137 ? 173.864 51.955 25.970 1.00 59.34 ? 135 ALA B CA 1 ATOM 4077 C C . ALA B 1 137 ? 175.291 51.458 25.725 1.00 55.13 ? 135 ALA B C 1 ATOM 4078 O O . ALA B 1 137 ? 175.517 50.268 25.536 1.00 53.37 ? 135 ALA B O 1 ATOM 4079 C CB . ALA B 1 137 ? 173.379 51.550 27.359 1.00 60.10 ? 135 ALA B CB 1 ATOM 4080 N N . ILE B 1 138 ? 176.247 52.393 25.711 1.00 47.83 ? 136 ILE B N 1 ATOM 4081 C CA . ILE B 1 138 ? 177.675 52.101 25.581 1.00 44.78 ? 136 ILE B CA 1 ATOM 4082 C C . ILE B 1 138 ? 178.213 52.089 26.978 1.00 43.29 ? 136 ILE B C 1 ATOM 4083 O O . ILE B 1 138 ? 178.127 53.092 27.705 1.00 42.82 ? 136 ILE B O 1 ATOM 4084 C CB . ILE B 1 138 ? 178.428 53.084 24.625 1.00 46.98 ? 136 ILE B CB 1 ATOM 4085 C CG1 . ILE B 1 138 ? 178.175 52.720 23.137 1.00 46.88 ? 136 ILE B CG1 1 ATOM 4086 C CG2 . ILE B 1 138 ? 179.938 53.233 24.934 1.00 46.00 ? 136 ILE B CG2 1 ATOM 4087 C CD1 . ILE B 1 138 ? 178.767 51.489 22.660 1.00 47.57 ? 136 ILE B CD1 1 ATOM 4088 N N . THR B 1 139 ? 178.771 50.958 27.357 1.00 36.90 ? 137 THR B N 1 ATOM 4089 C CA . THR B 1 139 ? 179.299 50.816 28.695 1.00 36.73 ? 137 THR B CA 1 ATOM 4090 C C . THR B 1 139 ? 180.675 51.561 28.836 1.00 39.30 ? 137 THR B C 1 ATOM 4091 O O . THR B 1 139 ? 180.831 52.390 29.750 1.00 41.25 ? 137 THR B O 1 ATOM 4092 C CB . THR B 1 139 ? 179.255 49.352 29.091 1.00 42.03 ? 137 THR B CB 1 ATOM 4093 O OG1 . THR B 1 139 ? 177.863 49.061 29.301 1.00 36.92 ? 137 THR B OG1 1 ATOM 4094 C CG2 . THR B 1 139 ? 180.048 49.060 30.359 1.00 38.36 ? 137 THR B CG2 1 ATOM 4095 N N . GLY B 1 140 ? 181.607 51.305 27.933 1.00 29.58 ? 138 GLY B N 1 ATOM 4096 C CA . GLY B 1 140 ? 182.900 51.970 27.951 1.00 26.76 ? 138 GLY B CA 1 ATOM 4097 C C . GLY B 1 140 ? 183.432 52.058 26.553 1.00 28.44 ? 138 GLY B C 1 ATOM 4098 O O . GLY B 1 140 ? 182.903 51.395 25.663 1.00 29.09 ? 138 GLY B O 1 ATOM 4099 N N . VAL B 1 141 ? 184.498 52.845 26.343 1.00 22.59 ? 139 VAL B N 1 ATOM 4100 C CA . VAL B 1 141 ? 185.110 53.017 25.015 1.00 19.48 ? 139 VAL B CA 1 ATOM 4101 C C . VAL B 1 141 ? 186.552 52.535 25.010 1.00 20.76 ? 139 VAL B C 1 ATOM 4102 O O . VAL B 1 141 ? 187.319 52.868 25.908 1.00 19.66 ? 139 VAL B O 1 ATOM 4103 C CB . VAL B 1 141 ? 184.964 54.494 24.534 1.00 22.57 ? 139 VAL B CB 1 ATOM 4104 C CG1 . VAL B 1 141 ? 185.721 54.773 23.229 1.00 21.71 ? 139 VAL B CG1 1 ATOM 4105 C CG2 . VAL B 1 141 ? 183.491 54.881 24.397 1.00 22.56 ? 139 VAL B CG2 1 ATOM 4106 N N . ILE B 1 142 ? 186.914 51.782 23.969 1.00 18.37 ? 140 ILE B N 1 ATOM 4107 C CA . ILE B 1 142 ? 188.260 51.287 23.668 1.00 18.43 ? 140 ILE B CA 1 ATOM 4108 C C . ILE B 1 142 ? 188.821 52.130 22.509 1.00 24.22 ? 140 ILE B C 1 ATOM 4109 O O . ILE B 1 142 ? 188.337 52.021 21.367 1.00 24.23 ? 140 ILE B O 1 ATOM 4110 C CB . ILE B 1 142 ? 188.217 49.767 23.311 1.00 21.18 ? 140 ILE B CB 1 ATOM 4111 C CG1 . ILE B 1 142 ? 187.536 48.926 24.437 1.00 22.02 ? 140 ILE B CG1 1 ATOM 4112 C CG2 . ILE B 1 142 ? 189.617 49.221 22.943 1.00 20.25 ? 140 ILE B CG2 1 ATOM 4113 C CD1 . ILE B 1 142 ? 188.387 48.624 25.663 1.00 25.68 ? 140 ILE B CD1 1 ATOM 4114 N N . GLY B 1 143 ? 189.807 52.971 22.820 1.00 21.00 ? 141 GLY B N 1 ATOM 4115 C CA . GLY B 1 143 ? 190.459 53.852 21.848 1.00 20.53 ? 141 GLY B CA 1 ATOM 4116 C C . GLY B 1 143 ? 190.720 55.261 22.345 1.00 24.12 ? 141 GLY B C 1 ATOM 4117 O O . GLY B 1 143 ? 190.459 55.560 23.509 1.00 23.13 ? 141 GLY B O 1 ATOM 4118 N N . GLY B 1 144 ? 191.238 56.145 21.483 1.00 20.23 ? 142 GLY B N 1 ATOM 4119 C CA . GLY B 1 144 ? 191.635 55.858 20.116 1.00 19.07 ? 142 GLY B CA 1 ATOM 4120 C C . GLY B 1 144 ? 193.117 55.563 19.998 1.00 23.99 ? 142 GLY B C 1 ATOM 4121 O O . GLY B 1 144 ? 193.762 55.072 20.948 1.00 23.37 ? 142 GLY B O 1 ATOM 4122 N N . SER B 1 145 ? 193.655 55.777 18.798 1.00 21.09 ? 143 SER B N 1 ATOM 4123 C CA . SER B 1 145 ? 195.073 55.522 18.587 1.00 22.47 ? 143 SER B CA 1 ATOM 4124 C C . SER B 1 145 ? 195.817 56.815 18.859 1.00 28.45 ? 143 SER B C 1 ATOM 4125 O O . SER B 1 145 ? 196.509 56.915 19.868 1.00 30.02 ? 143 SER B O 1 ATOM 4126 C CB . SER B 1 145 ? 195.348 55.001 17.175 1.00 25.96 ? 143 SER B CB 1 ATOM 4127 O OG . SER B 1 145 ? 194.841 53.685 17.021 1.00 35.26 ? 143 SER B OG 1 ATOM 4128 N N . TYR B 1 146 ? 195.607 57.813 17.995 1.00 23.05 ? 144 TYR B N 1 ATOM 4129 C CA . TYR B 1 146 ? 196.210 59.120 18.068 1.00 22.23 ? 144 TYR B CA 1 ATOM 4130 C C . TYR B 1 146 ? 195.771 59.866 19.312 1.00 24.12 ? 144 TYR B C 1 ATOM 4131 O O . TYR B 1 146 ? 194.585 59.888 19.624 1.00 21.25 ? 144 TYR B O 1 ATOM 4132 C CB . TYR B 1 146 ? 195.828 59.940 16.829 1.00 22.58 ? 144 TYR B CB 1 ATOM 4133 C CG . TYR B 1 146 ? 196.368 59.425 15.518 1.00 22.21 ? 144 TYR B CG 1 ATOM 4134 C CD1 . TYR B 1 146 ? 197.667 59.715 15.117 1.00 23.63 ? 144 TYR B CD1 1 ATOM 4135 C CD2 . TYR B 1 146 ? 195.549 58.725 14.630 1.00 22.66 ? 144 TYR B CD2 1 ATOM 4136 C CE1 . TYR B 1 146 ? 198.156 59.283 13.889 1.00 25.43 ? 144 TYR B CE1 1 ATOM 4137 C CE2 . TYR B 1 146 ? 196.021 58.295 13.397 1.00 22.86 ? 144 TYR B CE2 1 ATOM 4138 C CZ . TYR B 1 146 ? 197.324 58.583 13.023 1.00 33.78 ? 144 TYR B CZ 1 ATOM 4139 O OH . TYR B 1 146 ? 197.798 58.186 11.787 1.00 34.47 ? 144 TYR B OH 1 ATOM 4140 N N . SER B 1 147 ? 196.736 60.520 19.981 1.00 22.79 ? 145 SER B N 1 ATOM 4141 C CA . SER B 1 147 ? 196.548 61.323 21.201 1.00 22.24 ? 145 SER B CA 1 ATOM 4142 C C . SER B 1 147 ? 195.509 62.407 21.052 1.00 28.85 ? 145 SER B C 1 ATOM 4143 O O . SER B 1 147 ? 194.626 62.495 21.919 1.00 29.48 ? 145 SER B O 1 ATOM 4144 C CB . SER B 1 147 ? 197.862 61.924 21.664 1.00 20.76 ? 145 SER B CB 1 ATOM 4145 O OG . SER B 1 147 ? 198.542 60.957 22.447 1.00 23.18 ? 145 SER B OG 1 ATOM 4146 N N . ASP B 1 148 ? 195.573 63.189 19.943 1.00 25.49 ? 146 ASP B N 1 ATOM 4147 C CA . ASP B 1 148 ? 194.633 64.278 19.650 1.00 25.88 ? 146 ASP B CA 1 ATOM 4148 C C . ASP B 1 148 ? 193.200 63.757 19.559 1.00 29.53 ? 146 ASP B C 1 ATOM 4149 O O . ASP B 1 148 ? 192.297 64.386 20.102 1.00 29.91 ? 146 ASP B O 1 ATOM 4150 C CB . ASP B 1 148 ? 195.058 65.110 18.413 1.00 29.54 ? 146 ASP B CB 1 ATOM 4151 C CG . ASP B 1 148 ? 194.900 64.468 17.034 1.00 57.92 ? 146 ASP B CG 1 ATOM 4152 O OD1 . ASP B 1 148 ? 195.196 63.247 16.898 1.00 62.69 ? 146 ASP B OD1 1 ATOM 4153 O OD2 . ASP B 1 148 ? 194.529 65.196 16.075 1.00 65.61 ? 146 ASP B OD2 1 ATOM 4154 N N . VAL B 1 149 ? 193.018 62.546 18.979 1.00 24.05 ? 147 VAL B N 1 ATOM 4155 C CA . VAL B 1 149 ? 191.734 61.845 18.895 1.00 21.65 ? 147 VAL B CA 1 ATOM 4156 C C . VAL B 1 149 ? 191.298 61.442 20.310 1.00 23.29 ? 147 VAL B C 1 ATOM 4157 O O . VAL B 1 149 ? 190.187 61.764 20.689 1.00 24.78 ? 147 VAL B O 1 ATOM 4158 C CB . VAL B 1 149 ? 191.790 60.633 17.909 1.00 23.67 ? 147 VAL B CB 1 ATOM 4159 C CG1 . VAL B 1 149 ? 190.611 59.698 18.098 1.00 22.99 ? 147 VAL B CG1 1 ATOM 4160 C CG2 . VAL B 1 149 ? 191.876 61.096 16.458 1.00 22.77 ? 147 VAL B CG2 1 ATOM 4161 N N . SER B 1 150 ? 192.169 60.802 21.101 1.00 18.11 ? 148 SER B N 1 ATOM 4162 C CA . SER B 1 150 ? 191.838 60.364 22.478 1.00 17.60 ? 148 SER B CA 1 ATOM 4163 C C . SER B 1 150 ? 191.512 61.480 23.427 1.00 24.13 ? 148 SER B C 1 ATOM 4164 O O . SER B 1 150 ? 190.686 61.269 24.319 1.00 24.28 ? 148 SER B O 1 ATOM 4165 C CB . SER B 1 150 ? 192.944 59.508 23.090 1.00 16.25 ? 148 SER B CB 1 ATOM 4166 O OG . SER B 1 150 ? 192.937 58.200 22.548 1.00 19.63 ? 148 SER B OG 1 ATOM 4167 N N . ILE B 1 151 ? 192.218 62.630 23.305 1.00 20.50 ? 149 ILE B N 1 ATOM 4168 C CA . ILE B 1 151 ? 192.006 63.799 24.164 1.00 20.35 ? 149 ILE B CA 1 ATOM 4169 C C . ILE B 1 151 ? 190.633 64.419 23.920 1.00 25.54 ? 149 ILE B C 1 ATOM 4170 O O . ILE B 1 151 ? 189.907 64.708 24.872 1.00 26.00 ? 149 ILE B O 1 ATOM 4171 C CB . ILE B 1 151 ? 193.169 64.818 24.039 1.00 23.10 ? 149 ILE B CB 1 ATOM 4172 C CG1 . ILE B 1 151 ? 194.429 64.235 24.719 1.00 24.50 ? 149 ILE B CG1 1 ATOM 4173 C CG2 . ILE B 1 151 ? 192.808 66.160 24.643 1.00 20.79 ? 149 ILE B CG2 1 ATOM 4174 C CD1 . ILE B 1 151 ? 195.721 64.752 24.302 1.00 21.82 ? 149 ILE B CD1 1 ATOM 4175 N N . GLN B 1 152 ? 190.274 64.605 22.658 1.00 22.80 ? 150 GLN B N 1 ATOM 4176 C CA . GLN B 1 152 ? 188.994 65.217 22.283 1.00 23.35 ? 150 GLN B CA 1 ATOM 4177 C C . GLN B 1 152 ? 187.841 64.348 22.669 1.00 24.92 ? 150 GLN B C 1 ATOM 4178 O O . GLN B 1 152 ? 186.808 64.858 23.125 1.00 23.57 ? 150 GLN B O 1 ATOM 4179 C CB . GLN B 1 152 ? 188.922 65.482 20.770 1.00 25.00 ? 150 GLN B CB 1 ATOM 4180 C CG . GLN B 1 152 ? 190.153 66.135 20.249 1.00 46.58 ? 150 GLN B CG 1 ATOM 4181 C CD . GLN B 1 152 ? 190.039 67.599 20.320 1.00 65.46 ? 150 GLN B CD 1 ATOM 4182 O OE1 . GLN B 1 152 ? 189.466 68.215 19.409 1.00 63.27 ? 150 GLN B OE1 1 ATOM 4183 N NE2 . GLN B 1 152 ? 190.599 68.169 21.396 1.00 49.47 ? 150 GLN B NE2 1 ATOM 4184 N N . VAL B 1 153 ? 188.030 63.027 22.495 1.00 19.90 ? 151 VAL B N 1 ATOM 4185 C CA . VAL B 1 153 ? 187.005 62.046 22.777 1.00 18.14 ? 151 VAL B CA 1 ATOM 4186 C C . VAL B 1 153 ? 186.768 61.994 24.248 1.00 21.97 ? 151 VAL B C 1 ATOM 4187 O O . VAL B 1 153 ? 185.624 62.079 24.664 1.00 24.50 ? 151 VAL B O 1 ATOM 4188 C CB . VAL B 1 153 ? 187.316 60.709 22.100 1.00 20.04 ? 151 VAL B CB 1 ATOM 4189 C CG1 . VAL B 1 153 ? 186.449 59.588 22.642 1.00 19.06 ? 151 VAL B CG1 1 ATOM 4190 C CG2 . VAL B 1 153 ? 187.122 60.849 20.594 1.00 19.47 ? 151 VAL B CG2 1 ATOM 4191 N N . ALA B 1 154 ? 187.829 62.045 25.022 1.00 18.99 ? 152 ALA B N 1 ATOM 4192 C CA . ALA B 1 154 ? 187.790 62.064 26.482 1.00 19.40 ? 152 ALA B CA 1 ATOM 4193 C C . ALA B 1 154 ? 187.125 63.319 26.970 1.00 26.68 ? 152 ALA B C 1 ATOM 4194 O O . ALA B 1 154 ? 186.340 63.241 27.912 1.00 28.86 ? 152 ALA B O 1 ATOM 4195 C CB . ALA B 1 154 ? 189.193 61.953 27.053 1.00 19.92 ? 152 ALA B CB 1 ATOM 4196 N N . ASN B 1 155 ? 187.379 64.466 26.311 1.00 23.90 ? 153 ASN B N 1 ATOM 4197 C CA . ASN B 1 155 ? 186.726 65.725 26.673 1.00 24.26 ? 153 ASN B CA 1 ATOM 4198 C C . ASN B 1 155 ? 185.209 65.617 26.566 1.00 29.79 ? 153 ASN B C 1 ATOM 4199 O O . ASN B 1 155 ? 184.521 66.234 27.374 1.00 31.16 ? 153 ASN B O 1 ATOM 4200 C CB . ASN B 1 155 ? 187.273 66.910 25.884 1.00 21.65 ? 153 ASN B CB 1 ATOM 4201 C CG . ASN B 1 155 ? 188.625 67.358 26.372 1.00 38.76 ? 153 ASN B CG 1 ATOM 4202 O OD1 . ASN B 1 155 ? 189.098 66.955 27.443 1.00 37.07 ? 153 ASN B OD1 1 ATOM 4203 N ND2 . ASN B 1 155 ? 189.296 68.184 25.586 1.00 27.57 ? 153 ASN B ND2 1 ATOM 4204 N N . LEU B 1 156 ? 184.707 64.755 25.653 1.00 24.67 ? 154 LEU B N 1 ATOM 4205 C CA . LEU B 1 156 ? 183.287 64.481 25.486 1.00 24.12 ? 154 LEU B CA 1 ATOM 4206 C C . LEU B 1 156 ? 182.778 63.361 26.407 1.00 27.86 ? 154 LEU B C 1 ATOM 4207 O O . LEU B 1 156 ? 181.740 63.550 27.045 1.00 28.97 ? 154 LEU B O 1 ATOM 4208 C CB . LEU B 1 156 ? 182.937 64.146 24.015 1.00 24.07 ? 154 LEU B CB 1 ATOM 4209 C CG . LEU B 1 156 ? 181.442 63.809 23.727 1.00 27.97 ? 154 LEU B CG 1 ATOM 4210 C CD1 . LEU B 1 156 ? 180.540 65.057 23.842 1.00 28.41 ? 154 LEU B CD1 1 ATOM 4211 C CD2 . LEU B 1 156 ? 181.271 63.118 22.387 1.00 27.34 ? 154 LEU B CD2 1 ATOM 4212 N N . LEU B 1 157 ? 183.449 62.188 26.430 1.00 22.24 ? 155 LEU B N 1 ATOM 4213 C CA . LEU B 1 157 ? 182.991 61.056 27.246 1.00 21.40 ? 155 LEU B CA 1 ATOM 4214 C C . LEU B 1 157 ? 182.940 61.342 28.723 1.00 25.70 ? 155 LEU B C 1 ATOM 4215 O O . LEU B 1 157 ? 182.045 60.816 29.382 1.00 25.10 ? 155 LEU B O 1 ATOM 4216 C CB . LEU B 1 157 ? 183.774 59.764 26.999 1.00 21.28 ? 155 LEU B CB 1 ATOM 4217 C CG . LEU B 1 157 ? 184.008 59.278 25.538 1.00 24.19 ? 155 LEU B CG 1 ATOM 4218 C CD1 . LEU B 1 157 ? 185.004 58.112 25.522 1.00 23.26 ? 155 LEU B CD1 1 ATOM 4219 C CD2 . LEU B 1 157 ? 182.697 58.909 24.815 1.00 22.84 ? 155 LEU B CD2 1 ATOM 4220 N N . ARG B 1 158 ? 183.844 62.209 29.253 1.00 23.68 ? 156 ARG B N 1 ATOM 4221 C CA . ARG B 1 158 ? 183.822 62.578 30.687 1.00 24.08 ? 156 ARG B CA 1 ATOM 4222 C C . ARG B 1 158 ? 182.490 63.247 31.134 1.00 29.44 ? 156 ARG B C 1 ATOM 4223 O O . ARG B 1 158 ? 182.041 63.022 32.270 1.00 29.37 ? 156 ARG B O 1 ATOM 4224 C CB . ARG B 1 158 ? 185.032 63.426 31.097 1.00 21.42 ? 156 ARG B CB 1 ATOM 4225 C CG . ARG B 1 158 ? 184.982 64.877 30.663 1.00 28.83 ? 156 ARG B CG 1 ATOM 4226 C CD . ARG B 1 158 ? 185.975 65.704 31.451 1.00 32.32 ? 156 ARG B CD 1 ATOM 4227 N NE . ARG B 1 158 ? 185.559 65.915 32.838 1.00 37.01 ? 156 ARG B NE 1 ATOM 4228 C CZ . ARG B 1 158 ? 184.816 66.937 33.262 1.00 52.67 ? 156 ARG B CZ 1 ATOM 4229 N NH1 . ARG B 1 158 ? 184.378 67.854 32.403 1.00 24.42 ? 156 ARG B NH1 1 ATOM 4230 N NH2 . ARG B 1 158 ? 184.503 67.048 34.548 1.00 48.94 ? 156 ARG B NH2 1 ATOM 4231 N N . LEU B 1 159 ? 181.857 64.028 30.217 1.00 24.58 ? 157 LEU B N 1 ATOM 4232 C CA . LEU B 1 159 ? 180.594 64.718 30.434 1.00 24.61 ? 157 LEU B CA 1 ATOM 4233 C C . LEU B 1 159 ? 179.412 63.771 30.671 1.00 29.08 ? 157 LEU B C 1 ATOM 4234 O O . LEU B 1 159 ? 178.372 64.195 31.182 1.00 30.21 ? 157 LEU B O 1 ATOM 4235 C CB . LEU B 1 159 ? 180.282 65.596 29.213 1.00 24.74 ? 157 LEU B CB 1 ATOM 4236 C CG . LEU B 1 159 ? 181.221 66.739 28.936 1.00 28.74 ? 157 LEU B CG 1 ATOM 4237 C CD1 . LEU B 1 159 ? 180.767 67.509 27.738 1.00 29.10 ? 157 LEU B CD1 1 ATOM 4238 C CD2 . LEU B 1 159 ? 181.377 67.636 30.135 1.00 27.70 ? 157 LEU B CD2 1 ATOM 4239 N N . PHE B 1 160 ? 179.554 62.528 30.244 1.00 23.88 ? 158 PHE B N 1 ATOM 4240 C CA . PHE B 1 160 ? 178.528 61.506 30.307 1.00 24.14 ? 158 PHE B CA 1 ATOM 4241 C C . PHE B 1 160 ? 179.043 60.361 31.159 1.00 29.87 ? 158 PHE B C 1 ATOM 4242 O O . PHE B 1 160 ? 178.414 59.311 31.282 1.00 30.02 ? 158 PHE B O 1 ATOM 4243 C CB . PHE B 1 160 ? 178.186 61.073 28.858 1.00 26.07 ? 158 PHE B CB 1 ATOM 4244 C CG . PHE B 1 160 ? 177.680 62.252 28.045 1.00 27.89 ? 158 PHE B CG 1 ATOM 4245 C CD1 . PHE B 1 160 ? 176.341 62.636 28.100 1.00 30.32 ? 158 PHE B CD1 1 ATOM 4246 C CD2 . PHE B 1 160 ? 178.559 63.044 27.314 1.00 30.22 ? 158 PHE B CD2 1 ATOM 4247 C CE1 . PHE B 1 160 ? 175.885 63.755 27.398 1.00 30.18 ? 158 PHE B CE1 1 ATOM 4248 C CE2 . PHE B 1 160 ? 178.098 64.146 26.595 1.00 32.84 ? 158 PHE B CE2 1 ATOM 4249 C CZ . PHE B 1 160 ? 176.758 64.476 26.623 1.00 30.28 ? 158 PHE B CZ 1 ATOM 4250 N N . GLN B 1 161 ? 180.179 60.619 31.808 1.00 27.10 ? 159 GLN B N 1 ATOM 4251 C CA . GLN B 1 161 ? 180.918 59.741 32.690 1.00 26.97 ? 159 GLN B CA 1 ATOM 4252 C C . GLN B 1 161 ? 181.065 58.330 32.076 1.00 31.50 ? 159 GLN B C 1 ATOM 4253 O O . GLN B 1 161 ? 180.660 57.324 32.670 1.00 32.23 ? 159 GLN B O 1 ATOM 4254 C CB . GLN B 1 161 ? 180.405 59.750 34.150 1.00 28.66 ? 159 GLN B CB 1 ATOM 4255 C CG . GLN B 1 161 ? 178.933 60.041 34.457 1.00 53.91 ? 159 GLN B CG 1 ATOM 4256 C CD . GLN B 1 161 ? 178.529 61.476 34.271 1.00 68.52 ? 159 GLN B CD 1 ATOM 4257 O OE1 . GLN B 1 161 ? 179.258 62.424 34.613 1.00 61.53 ? 159 GLN B OE1 1 ATOM 4258 N NE2 . GLN B 1 161 ? 177.350 61.652 33.694 1.00 59.83 ? 159 GLN B NE2 1 ATOM 4259 N N . ILE B 1 162 ? 181.647 58.286 30.849 1.00 26.14 ? 160 ILE B N 1 ATOM 4260 C CA . ILE B 1 162 ? 181.893 57.044 30.111 1.00 25.84 ? 160 ILE B CA 1 ATOM 4261 C C . ILE B 1 162 ? 183.357 56.665 30.221 1.00 27.57 ? 160 ILE B C 1 ATOM 4262 O O . ILE B 1 162 ? 184.203 57.373 29.679 1.00 28.56 ? 160 ILE B O 1 ATOM 4263 C CB . ILE B 1 162 ? 181.426 57.052 28.610 1.00 29.09 ? 160 ILE B CB 1 ATOM 4264 C CG1 . ILE B 1 162 ? 179.902 57.292 28.451 1.00 28.24 ? 160 ILE B CG1 1 ATOM 4265 C CG2 . ILE B 1 162 ? 181.866 55.755 27.885 1.00 30.71 ? 160 ILE B CG2 1 ATOM 4266 C CD1 . ILE B 1 162 ? 179.509 57.774 27.017 1.00 32.77 ? 160 ILE B CD1 1 ATOM 4267 N N . PRO B 1 163 ? 183.676 55.525 30.845 1.00 20.70 ? 161 PRO B N 1 ATOM 4268 C CA . PRO B 1 163 ? 185.087 55.107 30.912 1.00 20.81 ? 161 PRO B CA 1 ATOM 4269 C C . PRO B 1 163 ? 185.750 54.896 29.520 1.00 24.51 ? 161 PRO B C 1 ATOM 4270 O O . PRO B 1 163 ? 185.127 54.356 28.602 1.00 24.26 ? 161 PRO B O 1 ATOM 4271 C CB . PRO B 1 163 ? 185.039 53.811 31.751 1.00 22.01 ? 161 PRO B CB 1 ATOM 4272 C CG . PRO B 1 163 ? 183.712 53.790 32.383 1.00 25.24 ? 161 PRO B CG 1 ATOM 4273 C CD . PRO B 1 163 ? 182.789 54.555 31.507 1.00 21.01 ? 161 PRO B CD 1 ATOM 4274 N N . GLN B 1 164 ? 187.022 55.309 29.381 1.00 19.81 ? 162 GLN B N 1 ATOM 4275 C CA . GLN B 1 164 ? 187.776 55.197 28.142 1.00 19.28 ? 162 GLN B CA 1 ATOM 4276 C C . GLN B 1 164 ? 189.143 54.578 28.368 1.00 25.18 ? 162 GLN B C 1 ATOM 4277 O O . GLN B 1 164 ? 189.880 55.035 29.243 1.00 24.45 ? 162 GLN B O 1 ATOM 4278 C CB . GLN B 1 164 ? 187.917 56.577 27.482 1.00 19.88 ? 162 GLN B CB 1 ATOM 4279 C CG . GLN B 1 164 ? 188.691 56.567 26.167 1.00 15.32 ? 162 GLN B CG 1 ATOM 4280 C CD . GLN B 1 164 ? 188.913 57.950 25.588 1.00 29.27 ? 162 GLN B CD 1 ATOM 4281 O OE1 . GLN B 1 164 ? 188.428 58.943 26.112 1.00 19.51 ? 162 GLN B OE1 1 ATOM 4282 N NE2 . GLN B 1 164 ? 189.679 58.048 24.498 1.00 25.74 ? 162 GLN B NE2 1 ATOM 4283 N N . ILE B 1 165 ? 189.488 53.539 27.563 1.00 22.68 ? 163 ILE B N 1 ATOM 4284 C CA . ILE B 1 165 ? 190.796 52.887 27.622 1.00 22.52 ? 163 ILE B CA 1 ATOM 4285 C C . ILE B 1 165 ? 191.455 52.932 26.251 1.00 27.64 ? 163 ILE B C 1 ATOM 4286 O O . ILE B 1 165 ? 190.954 52.321 25.306 1.00 27.63 ? 163 ILE B O 1 ATOM 4287 C CB . ILE B 1 165 ? 190.855 51.453 28.268 1.00 24.93 ? 163 ILE B CB 1 ATOM 4288 C CG1 . ILE B 1 165 ? 190.108 51.368 29.633 1.00 24.97 ? 163 ILE B CG1 1 ATOM 4289 C CG2 . ILE B 1 165 ? 192.339 50.965 28.384 1.00 22.93 ? 163 ILE B CG2 1 ATOM 4290 C CD1 . ILE B 1 165 ? 190.059 49.955 30.271 1.00 32.32 ? 163 ILE B CD1 1 ATOM 4291 N N . SER B 1 166 ? 192.575 53.656 26.147 1.00 23.82 ? 164 SER B N 1 ATOM 4292 C CA . SER B 1 166 ? 193.330 53.738 24.908 1.00 22.54 ? 164 SER B CA 1 ATOM 4293 C C . SER B 1 166 ? 194.370 52.636 24.901 1.00 28.24 ? 164 SER B C 1 ATOM 4294 O O . SER B 1 166 ? 194.846 52.244 25.959 1.00 32.55 ? 164 SER B O 1 ATOM 4295 C CB . SER B 1 166 ? 193.991 55.097 24.754 1.00 22.53 ? 164 SER B CB 1 ATOM 4296 O OG . SER B 1 166 ? 194.919 55.008 23.688 1.00 29.52 ? 164 SER B OG 1 ATOM 4297 N N . TYR B 1 167 ? 194.738 52.152 23.721 1.00 21.62 ? 165 TYR B N 1 ATOM 4298 C CA . TYR B 1 167 ? 195.686 51.054 23.511 1.00 19.55 ? 165 TYR B CA 1 ATOM 4299 C C . TYR B 1 167 ? 196.970 51.549 22.825 1.00 22.42 ? 165 TYR B C 1 ATOM 4300 O O . TYR B 1 167 ? 197.867 50.741 22.554 1.00 20.63 ? 165 TYR B O 1 ATOM 4301 C CB . TYR B 1 167 ? 195.013 49.985 22.612 1.00 19.20 ? 165 TYR B CB 1 ATOM 4302 C CG . TYR B 1 167 ? 194.302 50.580 21.417 1.00 18.68 ? 165 TYR B CG 1 ATOM 4303 C CD1 . TYR B 1 167 ? 195.020 51.089 20.335 1.00 21.08 ? 165 TYR B CD1 1 ATOM 4304 C CD2 . TYR B 1 167 ? 192.915 50.732 21.408 1.00 17.98 ? 165 TYR B CD2 1 ATOM 4305 C CE1 . TYR B 1 167 ? 194.377 51.722 19.267 1.00 22.42 ? 165 TYR B CE1 1 ATOM 4306 C CE2 . TYR B 1 167 ? 192.254 51.306 20.313 1.00 17.89 ? 165 TYR B CE2 1 ATOM 4307 C CZ . TYR B 1 167 ? 192.991 51.818 19.253 1.00 23.18 ? 165 TYR B CZ 1 ATOM 4308 O OH . TYR B 1 167 ? 192.382 52.521 18.234 1.00 15.40 ? 165 TYR B OH 1 ATOM 4309 N N . ALA B 1 168 ? 197.022 52.862 22.464 1.00 19.21 ? 166 ALA B N 1 ATOM 4310 C CA . ALA B 1 168 ? 198.135 53.475 21.716 1.00 17.56 ? 166 ALA B CA 1 ATOM 4311 C C . ALA B 1 168 ? 198.410 54.977 22.024 1.00 24.73 ? 166 ALA B C 1 ATOM 4312 O O . ALA B 1 168 ? 199.498 55.450 21.673 1.00 26.20 ? 166 ALA B O 1 ATOM 4313 C CB . ALA B 1 168 ? 197.923 53.279 20.229 1.00 16.93 ? 166 ALA B CB 1 ATOM 4314 N N . SER B 1 169 ? 197.464 55.729 22.661 1.00 20.77 ? 167 SER B N 1 ATOM 4315 C CA . SER B 1 169 ? 197.705 57.161 22.974 1.00 20.54 ? 167 SER B CA 1 ATOM 4316 C C . SER B 1 169 ? 198.735 57.342 24.073 1.00 27.24 ? 167 SER B C 1 ATOM 4317 O O . SER B 1 169 ? 198.519 56.927 25.214 1.00 26.79 ? 167 SER B O 1 ATOM 4318 C CB . SER B 1 169 ? 196.431 57.911 23.333 1.00 18.28 ? 167 SER B CB 1 ATOM 4319 O OG . SER B 1 169 ? 195.552 57.866 22.240 1.00 10.21 ? 167 SER B OG 1 ATOM 4320 N N . THR B 1 170 ? 199.850 57.971 23.730 1.00 24.70 ? 168 THR B N 1 ATOM 4321 C CA . THR B 1 170 ? 200.929 58.095 24.696 1.00 25.24 ? 168 THR B CA 1 ATOM 4322 C C . THR B 1 170 ? 201.158 59.528 25.219 1.00 29.12 ? 168 THR B C 1 ATOM 4323 O O . THR B 1 170 ? 202.054 59.707 26.026 1.00 27.56 ? 168 THR B O 1 ATOM 4324 C CB . THR B 1 170 ? 202.203 57.495 24.082 1.00 29.27 ? 168 THR B CB 1 ATOM 4325 O OG1 . THR B 1 170 ? 202.462 58.180 22.861 1.00 25.25 ? 168 THR B OG1 1 ATOM 4326 C CG2 . THR B 1 170 ? 202.111 55.982 23.836 1.00 25.57 ? 168 THR B CG2 1 ATOM 4327 N N . SER B 1 171 ? 200.356 60.533 24.805 1.00 27.09 ? 169 SER B N 1 ATOM 4328 C CA . SER B 1 171 ? 200.570 61.907 25.276 1.00 27.42 ? 169 SER B CA 1 ATOM 4329 C C . SER B 1 171 ? 200.531 61.983 26.788 1.00 34.90 ? 169 SER B C 1 ATOM 4330 O O . SER B 1 171 ? 199.594 61.471 27.418 1.00 35.05 ? 169 SER B O 1 ATOM 4331 C CB . SER B 1 171 ? 199.558 62.872 24.678 1.00 29.54 ? 169 SER B CB 1 ATOM 4332 O OG . SER B 1 171 ? 199.776 64.187 25.154 1.00 40.41 ? 169 SER B OG 1 ATOM 4333 N N . ALA B 1 172 ? 201.574 62.626 27.369 1.00 32.03 ? 170 ALA B N 1 ATOM 4334 C CA . ALA B 1 172 ? 201.741 62.810 28.810 1.00 30.23 ? 170 ALA B CA 1 ATOM 4335 C C . ALA B 1 172 ? 200.602 63.664 29.385 1.00 31.04 ? 170 ALA B C 1 ATOM 4336 O O . ALA B 1 172 ? 200.277 63.527 30.552 1.00 30.77 ? 170 ALA B O 1 ATOM 4337 C CB . ALA B 1 172 ? 203.098 63.417 29.109 1.00 30.44 ? 170 ALA B CB 1 ATOM 4338 N N . LYS B 1 173 ? 199.923 64.444 28.530 1.00 26.40 ? 171 LYS B N 1 ATOM 4339 C CA . LYS B 1 173 ? 198.759 65.274 28.865 1.00 25.71 ? 171 LYS B CA 1 ATOM 4340 C C . LYS B 1 173 ? 197.630 64.416 29.420 1.00 28.34 ? 171 LYS B C 1 ATOM 4341 O O . LYS B 1 173 ? 196.914 64.857 30.322 1.00 28.98 ? 171 LYS B O 1 ATOM 4342 C CB . LYS B 1 173 ? 198.255 66.030 27.621 1.00 27.51 ? 171 LYS B CB 1 ATOM 4343 C CG . LYS B 1 173 ? 199.071 67.269 27.325 1.00 44.97 ? 171 LYS B CG 1 ATOM 4344 C CD . LYS B 1 173 ? 198.361 68.244 26.378 1.00 54.77 ? 171 LYS B CD 1 ATOM 4345 C CE . LYS B 1 173 ? 198.945 69.635 26.545 1.00 60.60 ? 171 LYS B CE 1 ATOM 4346 N NZ . LYS B 1 173 ? 198.879 70.444 25.298 1.00 69.33 ? 171 LYS B NZ 1 ATOM 4347 N N . LEU B 1 174 ? 197.500 63.172 28.907 1.00 21.94 ? 172 LEU B N 1 ATOM 4348 C CA . LEU B 1 174 ? 196.450 62.245 29.324 1.00 20.54 ? 172 LEU B CA 1 ATOM 4349 C C . LEU B 1 174 ? 196.631 61.652 30.753 1.00 25.88 ? 172 LEU B C 1 ATOM 4350 O O . LEU B 1 174 ? 195.702 61.024 31.264 1.00 24.02 ? 172 LEU B O 1 ATOM 4351 C CB . LEU B 1 174 ? 196.276 61.149 28.283 1.00 19.37 ? 172 LEU B CB 1 ATOM 4352 C CG . LEU B 1 174 ? 195.542 61.549 26.987 1.00 19.55 ? 172 LEU B CG 1 ATOM 4353 C CD1 . LEU B 1 174 ? 195.834 60.559 25.910 1.00 17.46 ? 172 LEU B CD1 1 ATOM 4354 C CD2 . LEU B 1 174 ? 194.055 61.714 27.200 1.00 16.18 ? 172 LEU B CD2 1 ATOM 4355 N N . SER B 1 175 ? 197.785 61.930 31.420 1.00 24.17 ? 173 SER B N 1 ATOM 4356 C CA . SER B 1 175 ? 198.093 61.529 32.800 1.00 23.08 ? 173 SER B CA 1 ATOM 4357 C C . SER B 1 175 ? 197.430 62.446 33.801 1.00 29.33 ? 173 SER B C 1 ATOM 4358 O O . SER B 1 175 ? 197.341 62.096 34.976 1.00 30.82 ? 173 SER B O 1 ATOM 4359 C CB . SER B 1 175 ? 199.592 61.533 33.022 1.00 25.47 ? 173 SER B CB 1 ATOM 4360 O OG . SER B 1 175 ? 200.183 60.470 32.297 1.00 36.87 ? 173 SER B OG 1 ATOM 4361 N N . ASP B 1 176 ? 196.920 63.612 33.345 1.00 26.23 ? 174 ASP B N 1 ATOM 4362 C CA . ASP B 1 176 ? 196.246 64.589 34.203 1.00 25.10 ? 174 ASP B CA 1 ATOM 4363 C C . ASP B 1 176 ? 194.807 64.187 34.485 1.00 26.66 ? 174 ASP B C 1 ATOM 4364 O O . ASP B 1 176 ? 193.949 64.490 33.660 1.00 25.62 ? 174 ASP B O 1 ATOM 4365 C CB . ASP B 1 176 ? 196.290 66.004 33.559 1.00 27.48 ? 174 ASP B CB 1 ATOM 4366 C CG . ASP B 1 176 ? 195.797 67.133 34.474 1.00 37.46 ? 174 ASP B CG 1 ATOM 4367 O OD1 . ASP B 1 176 ? 195.321 66.830 35.600 1.00 37.39 ? 174 ASP B OD1 1 ATOM 4368 O OD2 . ASP B 1 176 ? 195.915 68.315 34.078 1.00 37.82 ? 174 ASP B OD2 1 ATOM 4369 N N . LYS B 1 177 ? 194.526 63.596 35.677 1.00 24.25 ? 175 LYS B N 1 ATOM 4370 C CA . LYS B 1 177 ? 193.173 63.194 36.123 1.00 24.06 ? 175 LYS B CA 1 ATOM 4371 C C . LYS B 1 177 ? 192.280 64.372 36.566 1.00 30.99 ? 175 LYS B C 1 ATOM 4372 O O . LYS B 1 177 ? 191.079 64.189 36.772 1.00 31.01 ? 175 LYS B O 1 ATOM 4373 C CB . LYS B 1 177 ? 193.192 62.090 37.207 1.00 25.04 ? 175 LYS B CB 1 ATOM 4374 C CG . LYS B 1 177 ? 193.802 60.711 36.831 1.00 34.36 ? 175 LYS B CG 1 ATOM 4375 C CD . LYS B 1 177 ? 193.359 60.077 35.489 1.00 39.29 ? 175 LYS B CD 1 ATOM 4376 C CE . LYS B 1 177 ? 194.383 60.358 34.404 1.00 41.99 ? 175 LYS B CE 1 ATOM 4377 N NZ . LYS B 1 177 ? 193.961 59.894 33.062 1.00 43.93 ? 175 LYS B NZ 1 ATOM 4378 N N . SER B 1 178 ? 192.817 65.582 36.653 1.00 29.74 ? 176 SER B N 1 ATOM 4379 C CA . SER B 1 178 ? 191.933 66.710 36.929 1.00 30.58 ? 176 SER B CA 1 ATOM 4380 C C . SER B 1 178 ? 191.180 67.068 35.634 1.00 35.04 ? 176 SER B C 1 ATOM 4381 O O . SER B 1 178 ? 190.072 67.604 35.698 1.00 36.91 ? 176 SER B O 1 ATOM 4382 C CB . SER B 1 178 ? 192.704 67.910 37.471 1.00 34.95 ? 176 SER B CB 1 ATOM 4383 O OG . SER B 1 178 ? 193.453 68.556 36.459 1.00 49.27 ? 176 SER B OG 1 ATOM 4384 N N . ARG B 1 179 ? 191.775 66.736 34.466 1.00 29.84 ? 177 ARG B N 1 ATOM 4385 C CA . ARG B 1 179 ? 191.196 66.976 33.136 1.00 29.17 ? 177 ARG B CA 1 ATOM 4386 C C . ARG B 1 179 ? 190.586 65.722 32.478 1.00 31.99 ? 177 ARG B C 1 ATOM 4387 O O . ARG B 1 179 ? 189.536 65.815 31.853 1.00 33.26 ? 177 ARG B O 1 ATOM 4388 C CB . ARG B 1 179 ? 192.238 67.589 32.189 1.00 27.49 ? 177 ARG B CB 1 ATOM 4389 C CG . ARG B 1 179 ? 192.660 68.973 32.596 1.00 35.69 ? 177 ARG B CG 1 ATOM 4390 C CD . ARG B 1 179 ? 193.768 69.495 31.722 1.00 53.66 ? 177 ARG B CD 1 ATOM 4391 N NE . ARG B 1 179 ? 193.291 70.026 30.444 1.00 64.36 ? 177 ARG B NE 1 ATOM 4392 C CZ . ARG B 1 179 ? 194.101 70.477 29.489 1.00 83.24 ? 177 ARG B CZ 1 ATOM 4393 N NH1 . ARG B 1 179 ? 195.420 70.454 29.661 1.00 61.51 ? 177 ARG B NH1 1 ATOM 4394 N NH2 . ARG B 1 179 ? 193.600 70.942 28.350 1.00 77.58 ? 177 ARG B NH2 1 ATOM 4395 N N . TYR B 1 180 ? 191.271 64.584 32.556 1.00 26.84 ? 178 TYR B N 1 ATOM 4396 C CA . TYR B 1 180 ? 190.857 63.329 31.912 1.00 26.06 ? 178 TYR B CA 1 ATOM 4397 C C . TYR B 1 180 ? 190.560 62.301 32.963 1.00 29.34 ? 178 TYR B C 1 ATOM 4398 O O . TYR B 1 180 ? 191.253 61.301 33.074 1.00 29.15 ? 178 TYR B O 1 ATOM 4399 C CB . TYR B 1 180 ? 191.936 62.874 30.901 1.00 25.88 ? 178 TYR B CB 1 ATOM 4400 C CG . TYR B 1 180 ? 192.373 64.033 30.022 1.00 25.36 ? 178 TYR B CG 1 ATOM 4401 C CD1 . TYR B 1 180 ? 191.515 64.565 29.060 1.00 26.08 ? 178 TYR B CD1 1 ATOM 4402 C CD2 . TYR B 1 180 ? 193.600 64.658 30.220 1.00 25.00 ? 178 TYR B CD2 1 ATOM 4403 C CE1 . TYR B 1 180 ? 191.882 65.664 28.291 1.00 25.68 ? 178 TYR B CE1 1 ATOM 4404 C CE2 . TYR B 1 180 ? 193.980 65.752 29.451 1.00 25.81 ? 178 TYR B CE2 1 ATOM 4405 C CZ . TYR B 1 180 ? 193.109 66.268 28.499 1.00 33.42 ? 178 TYR B CZ 1 ATOM 4406 O OH . TYR B 1 180 ? 193.467 67.366 27.736 1.00 28.69 ? 178 TYR B OH 1 ATOM 4407 N N . ASP B 1 181 ? 189.538 62.591 33.761 1.00 26.42 ? 179 ASP B N 1 ATOM 4408 C CA . ASP B 1 181 ? 189.132 61.826 34.937 1.00 27.25 ? 179 ASP B CA 1 ATOM 4409 C C . ASP B 1 181 ? 188.449 60.480 34.624 1.00 32.18 ? 179 ASP B C 1 ATOM 4410 O O . ASP B 1 181 ? 188.221 59.721 35.553 1.00 30.89 ? 179 ASP B O 1 ATOM 4411 C CB . ASP B 1 181 ? 188.266 62.685 35.905 1.00 29.25 ? 179 ASP B CB 1 ATOM 4412 C CG . ASP B 1 181 ? 187.204 63.579 35.291 1.00 47.47 ? 179 ASP B CG 1 ATOM 4413 O OD1 . ASP B 1 181 ? 187.512 64.267 34.290 1.00 51.11 ? 179 ASP B OD1 1 ATOM 4414 O OD2 . ASP B 1 181 ? 186.096 63.686 35.882 1.00 53.22 ? 179 ASP B OD2 1 ATOM 4415 N N . TYR B 1 182 ? 188.148 60.177 33.347 1.00 29.67 ? 180 TYR B N 1 ATOM 4416 C CA . TYR B 1 182 ? 187.490 58.916 32.941 1.00 29.10 ? 180 TYR B CA 1 ATOM 4417 C C . TYR B 1 182 ? 188.331 58.142 31.933 1.00 29.90 ? 180 TYR B C 1 ATOM 4418 O O . TYR B 1 182 ? 187.816 57.256 31.248 1.00 28.16 ? 180 TYR B O 1 ATOM 4419 C CB . TYR B 1 182 ? 186.093 59.213 32.353 1.00 30.82 ? 180 TYR B CB 1 ATOM 4420 C CG . TYR B 1 182 ? 185.074 59.475 33.426 1.00 33.22 ? 180 TYR B CG 1 ATOM 4421 C CD1 . TYR B 1 182 ? 184.891 60.754 33.941 1.00 34.95 ? 180 TYR B CD1 1 ATOM 4422 C CD2 . TYR B 1 182 ? 184.362 58.426 34.007 1.00 34.67 ? 180 TYR B CD2 1 ATOM 4423 C CE1 . TYR B 1 182 ? 183.989 60.993 34.980 1.00 36.11 ? 180 TYR B CE1 1 ATOM 4424 C CE2 . TYR B 1 182 ? 183.481 58.646 35.063 1.00 35.89 ? 180 TYR B CE2 1 ATOM 4425 C CZ . TYR B 1 182 ? 183.290 59.935 35.542 1.00 42.95 ? 180 TYR B CZ 1 ATOM 4426 O OH . TYR B 1 182 ? 182.373 60.165 36.541 1.00 41.26 ? 180 TYR B OH 1 ATOM 4427 N N . PHE B 1 183 ? 189.646 58.462 31.885 1.00 24.22 ? 181 PHE B N 1 ATOM 4428 C CA . PHE B 1 183 ? 190.597 57.917 30.928 1.00 21.33 ? 181 PHE B CA 1 ATOM 4429 C C . PHE B 1 183 ? 191.681 57.086 31.566 1.00 26.25 ? 181 PHE B C 1 ATOM 4430 O O . PHE B 1 183 ? 192.314 57.523 32.508 1.00 26.17 ? 181 PHE B O 1 ATOM 4431 C CB . PHE B 1 183 ? 191.241 59.078 30.144 1.00 20.84 ? 181 PHE B CB 1 ATOM 4432 C CG . PHE B 1 183 ? 192.219 58.649 29.080 1.00 19.00 ? 181 PHE B CG 1 ATOM 4433 C CD1 . PHE B 1 183 ? 193.562 58.460 29.383 1.00 19.68 ? 181 PHE B CD1 1 ATOM 4434 C CD2 . PHE B 1 183 ? 191.798 58.432 27.781 1.00 17.87 ? 181 PHE B CD2 1 ATOM 4435 C CE1 . PHE B 1 183 ? 194.455 58.044 28.414 1.00 19.45 ? 181 PHE B CE1 1 ATOM 4436 C CE2 . PHE B 1 183 ? 192.688 58.009 26.809 1.00 20.39 ? 181 PHE B CE2 1 ATOM 4437 C CZ . PHE B 1 183 ? 194.011 57.825 27.129 1.00 19.22 ? 181 PHE B CZ 1 ATOM 4438 N N . ALA B 1 184 ? 191.976 55.948 30.946 1.00 23.05 ? 182 ALA B N 1 ATOM 4439 C CA . ALA B 1 184 ? 193.049 55.023 31.295 1.00 22.14 ? 182 ALA B CA 1 ATOM 4440 C C . ALA B 1 184 ? 193.670 54.501 29.979 1.00 27.25 ? 182 ALA B C 1 ATOM 4441 O O . ALA B 1 184 ? 193.083 54.630 28.882 1.00 25.07 ? 182 ALA B O 1 ATOM 4442 C CB . ALA B 1 184 ? 192.513 53.861 32.123 1.00 22.28 ? 182 ALA B CB 1 ATOM 4443 N N . ARG B 1 185 ? 194.881 53.950 30.092 1.00 24.26 ? 183 ARG B N 1 ATOM 4444 C CA . ARG B 1 185 ? 195.585 53.379 28.953 1.00 22.84 ? 183 ARG B CA 1 ATOM 4445 C C . ARG B 1 185 ? 196.447 52.155 29.299 1.00 26.48 ? 183 ARG B C 1 ATOM 4446 O O . ARG B 1 185 ? 197.036 52.064 30.386 1.00 24.73 ? 183 ARG B O 1 ATOM 4447 C CB . ARG B 1 185 ? 196.416 54.431 28.263 1.00 18.17 ? 183 ARG B CB 1 ATOM 4448 C CG . ARG B 1 185 ? 197.070 55.399 29.202 1.00 17.63 ? 183 ARG B CG 1 ATOM 4449 C CD . ARG B 1 185 ? 197.858 56.369 28.364 1.00 23.35 ? 183 ARG B CD 1 ATOM 4450 N NE . ARG B 1 185 ? 198.453 57.423 29.170 1.00 26.88 ? 183 ARG B NE 1 ATOM 4451 C CZ . ARG B 1 185 ? 198.941 58.548 28.677 1.00 32.48 ? 183 ARG B CZ 1 ATOM 4452 N NH1 . ARG B 1 185 ? 198.905 58.775 27.374 1.00 23.69 ? 183 ARG B NH1 1 ATOM 4453 N NH2 . ARG B 1 185 ? 199.452 59.470 29.491 1.00 15.24 ? 183 ARG B NH2 1 ATOM 4454 N N . THR B 1 186 ? 196.517 51.218 28.353 1.00 24.10 ? 184 THR B N 1 ATOM 4455 C CA . THR B 1 186 ? 197.377 50.030 28.477 1.00 24.45 ? 184 THR B CA 1 ATOM 4456 C C . THR B 1 186 ? 198.840 50.391 28.030 1.00 30.28 ? 184 THR B C 1 ATOM 4457 O O . THR B 1 186 ? 199.696 49.517 27.852 1.00 30.91 ? 184 THR B O 1 ATOM 4458 C CB . THR B 1 186 ? 196.742 48.820 27.778 1.00 21.04 ? 184 THR B CB 1 ATOM 4459 O OG1 . THR B 1 186 ? 196.313 49.184 26.458 1.00 23.97 ? 184 THR B OG1 1 ATOM 4460 C CG2 . THR B 1 186 ? 195.596 48.258 28.562 1.00 12.49 ? 184 THR B CG2 1 ATOM 4461 N N . VAL B 1 187 ? 199.114 51.698 27.897 1.00 26.73 ? 185 VAL B N 1 ATOM 4462 C CA . VAL B 1 187 ? 200.404 52.197 27.452 1.00 27.64 ? 185 VAL B CA 1 ATOM 4463 C C . VAL B 1 187 ? 200.973 53.268 28.411 1.00 35.42 ? 185 VAL B C 1 ATOM 4464 O O . VAL B 1 187 ? 200.220 54.038 29.043 1.00 36.48 ? 185 VAL B O 1 ATOM 4465 C CB . VAL B 1 187 ? 200.394 52.698 25.964 1.00 31.07 ? 185 VAL B CB 1 ATOM 4466 C CG1 . VAL B 1 187 ? 200.100 51.579 24.973 1.00 30.00 ? 185 VAL B CG1 1 ATOM 4467 C CG2 . VAL B 1 187 ? 199.444 53.872 25.764 1.00 31.33 ? 185 VAL B CG2 1 ATOM 4468 N N . PRO B 1 188 ? 202.311 53.380 28.466 1.00 31.15 ? 186 PRO B N 1 ATOM 4469 C CA . PRO B 1 188 ? 202.904 54.415 29.313 1.00 31.15 ? 186 PRO B CA 1 ATOM 4470 C C . PRO B 1 188 ? 202.878 55.810 28.670 1.00 33.34 ? 186 PRO B C 1 ATOM 4471 O O . PRO B 1 188 ? 202.810 55.909 27.440 1.00 31.38 ? 186 PRO B O 1 ATOM 4472 C CB . PRO B 1 188 ? 204.342 53.918 29.464 1.00 33.72 ? 186 PRO B CB 1 ATOM 4473 C CG . PRO B 1 188 ? 204.623 53.222 28.142 1.00 37.70 ? 186 PRO B CG 1 ATOM 4474 C CD . PRO B 1 188 ? 203.345 52.557 27.799 1.00 32.27 ? 186 PRO B CD 1 ATOM 4475 N N . PRO B 1 189 ? 203.036 56.910 29.461 1.00 31.11 ? 187 PRO B N 1 ATOM 4476 C CA . PRO B 1 189 ? 203.119 58.243 28.832 1.00 30.06 ? 187 PRO B CA 1 ATOM 4477 C C . PRO B 1 189 ? 204.484 58.483 28.176 1.00 35.84 ? 187 PRO B C 1 ATOM 4478 O O . PRO B 1 189 ? 205.481 57.865 28.556 1.00 35.42 ? 187 PRO B O 1 ATOM 4479 C CB . PRO B 1 189 ? 202.866 59.204 29.991 1.00 31.19 ? 187 PRO B CB 1 ATOM 4480 C CG . PRO B 1 189 ? 203.149 58.436 31.237 1.00 34.89 ? 187 PRO B CG 1 ATOM 4481 C CD . PRO B 1 189 ? 203.167 56.989 30.942 1.00 31.55 ? 187 PRO B CD 1 ATOM 4482 N N . ASP B 1 190 ? 204.537 59.402 27.211 1.00 34.82 ? 188 ASP B N 1 ATOM 4483 C CA . ASP B 1 190 ? 205.745 59.736 26.459 1.00 35.94 ? 188 ASP B CA 1 ATOM 4484 C C . ASP B 1 190 ? 206.832 60.384 27.305 1.00 43.47 ? 188 ASP B C 1 ATOM 4485 O O . ASP B 1 190 ? 207.944 60.585 26.794 1.00 44.08 ? 188 ASP B O 1 ATOM 4486 C CB . ASP B 1 190 ? 205.420 60.583 25.225 1.00 38.04 ? 188 ASP B CB 1 ATOM 4487 C CG . ASP B 1 190 ? 204.763 59.775 24.128 1.00 52.72 ? 188 ASP B CG 1 ATOM 4488 O OD1 . ASP B 1 190 ? 204.988 58.542 24.078 1.00 52.44 ? 188 ASP B OD1 1 ATOM 4489 O OD2 . ASP B 1 190 ? 204.000 60.362 23.338 1.00 61.41 ? 188 ASP B OD2 1 ATOM 4490 N N . PHE B 1 191 ? 206.541 60.643 28.610 1.00 40.14 ? 189 PHE B N 1 ATOM 4491 C CA . PHE B 1 191 ? 207.508 61.141 29.586 1.00 40.56 ? 189 PHE B CA 1 ATOM 4492 C C . PHE B 1 191 ? 208.722 60.180 29.632 1.00 43.60 ? 189 PHE B C 1 ATOM 4493 O O . PHE B 1 191 ? 209.869 60.634 29.736 1.00 41.94 ? 189 PHE B O 1 ATOM 4494 C CB . PHE B 1 191 ? 206.841 61.243 30.961 1.00 42.69 ? 189 PHE B CB 1 ATOM 4495 C CG . PHE B 1 191 ? 207.758 61.391 32.148 1.00 44.91 ? 189 PHE B CG 1 ATOM 4496 C CD1 . PHE B 1 191 ? 208.122 62.648 32.611 1.00 47.65 ? 189 PHE B CD1 1 ATOM 4497 C CD2 . PHE B 1 191 ? 208.201 60.271 32.851 1.00 49.12 ? 189 PHE B CD2 1 ATOM 4498 C CE1 . PHE B 1 191 ? 208.940 62.788 33.733 1.00 49.06 ? 189 PHE B CE1 1 ATOM 4499 C CE2 . PHE B 1 191 ? 209.020 60.408 33.979 1.00 51.85 ? 189 PHE B CE2 1 ATOM 4500 C CZ . PHE B 1 191 ? 209.384 61.668 34.411 1.00 49.66 ? 189 PHE B CZ 1 ATOM 4501 N N . PHE B 1 192 ? 208.449 58.862 29.512 1.00 40.92 ? 190 PHE B N 1 ATOM 4502 C CA . PHE B 1 192 ? 209.464 57.797 29.507 1.00 41.33 ? 190 PHE B CA 1 ATOM 4503 C C . PHE B 1 192 ? 210.154 57.617 28.161 1.00 45.95 ? 190 PHE B C 1 ATOM 4504 O O . PHE B 1 192 ? 211.354 57.349 28.129 1.00 45.98 ? 190 PHE B O 1 ATOM 4505 C CB . PHE B 1 192 ? 208.881 56.474 29.992 1.00 42.59 ? 190 PHE B CB 1 ATOM 4506 C CG . PHE B 1 192 ? 208.298 56.572 31.372 1.00 43.53 ? 190 PHE B CG 1 ATOM 4507 C CD1 . PHE B 1 192 ? 209.122 56.562 32.493 1.00 46.74 ? 190 PHE B CD1 1 ATOM 4508 C CD2 . PHE B 1 192 ? 206.928 56.705 31.554 1.00 45.75 ? 190 PHE B CD2 1 ATOM 4509 C CE1 . PHE B 1 192 ? 208.586 56.691 33.772 1.00 48.07 ? 190 PHE B CE1 1 ATOM 4510 C CE2 . PHE B 1 192 ? 206.388 56.819 32.832 1.00 49.40 ? 190 PHE B CE2 1 ATOM 4511 C CZ . PHE B 1 192 ? 207.220 56.804 33.937 1.00 47.84 ? 190 PHE B CZ 1 ATOM 4512 N N . GLN B 1 193 ? 209.407 57.787 27.063 1.00 42.40 ? 191 GLN B N 1 ATOM 4513 C CA . GLN B 1 193 ? 209.923 57.685 25.698 1.00 42.10 ? 191 GLN B CA 1 ATOM 4514 C C . GLN B 1 193 ? 210.924 58.822 25.405 1.00 46.67 ? 191 GLN B C 1 ATOM 4515 O O . GLN B 1 193 ? 211.978 58.560 24.825 1.00 46.74 ? 191 GLN B O 1 ATOM 4516 C CB . GLN B 1 193 ? 208.764 57.670 24.687 1.00 42.82 ? 191 GLN B CB 1 ATOM 4517 C CG . GLN B 1 193 ? 209.223 57.444 23.265 1.00 45.06 ? 191 GLN B CG 1 ATOM 4518 C CD . GLN B 1 193 ? 208.145 57.095 22.264 1.00 49.21 ? 191 GLN B CD 1 ATOM 4519 O OE1 . GLN B 1 193 ? 208.448 56.585 21.198 1.00 38.11 ? 191 GLN B OE1 1 ATOM 4520 N NE2 . GLN B 1 193 ? 206.877 57.311 22.575 1.00 32.75 ? 191 GLN B NE2 1 ATOM 4521 N N . ALA B 1 194 ? 210.601 60.068 25.821 1.00 42.21 ? 192 ALA B N 1 ATOM 4522 C CA . ALA B 1 194 ? 211.467 61.237 25.639 1.00 41.74 ? 192 ALA B CA 1 ATOM 4523 C C . ALA B 1 194 ? 212.795 61.059 26.368 1.00 47.17 ? 192 ALA B C 1 ATOM 4524 O O . ALA B 1 194 ? 213.834 61.424 25.824 1.00 48.22 ? 192 ALA B O 1 ATOM 4525 C CB . ALA B 1 194 ? 210.769 62.483 26.137 1.00 42.50 ? 192 ALA B CB 1 ATOM 4526 N N . LYS B 1 195 ? 212.756 60.484 27.586 1.00 43.82 ? 193 LYS B N 1 ATOM 4527 C CA . LYS B 1 195 ? 213.909 60.170 28.424 1.00 44.30 ? 193 LYS B CA 1 ATOM 4528 C C . LYS B 1 195 ? 214.783 59.130 27.664 1.00 50.43 ? 193 LYS B C 1 ATOM 4529 O O . LYS B 1 195 ? 215.954 59.411 27.390 1.00 51.63 ? 193 LYS B O 1 ATOM 4530 C CB . LYS B 1 195 ? 213.409 59.622 29.766 1.00 46.58 ? 193 LYS B CB 1 ATOM 4531 C CG . LYS B 1 195 ? 214.368 59.755 30.911 1.00 58.73 ? 193 LYS B CG 1 ATOM 4532 C CD . LYS B 1 195 ? 213.595 59.959 32.208 1.00 73.80 ? 193 LYS B CD 1 ATOM 4533 C CE . LYS B 1 195 ? 214.341 60.828 33.204 1.00 93.10 ? 193 LYS B CE 1 ATOM 4534 N NZ . LYS B 1 195 ? 215.627 60.214 33.653 1.00 102.27 ? 193 LYS B NZ 1 ATOM 4535 N N . ALA B 1 196 ? 214.186 57.991 27.238 1.00 45.59 ? 194 ALA B N 1 ATOM 4536 C CA . ALA B 1 196 ? 214.860 56.966 26.436 1.00 45.51 ? 194 ALA B CA 1 ATOM 4537 C C . ALA B 1 196 ? 215.587 57.547 25.209 1.00 51.72 ? 194 ALA B C 1 ATOM 4538 O O . ALA B 1 196 ? 216.722 57.168 24.961 1.00 52.08 ? 194 ALA B O 1 ATOM 4539 C CB . ALA B 1 196 ? 213.856 55.919 25.974 1.00 46.03 ? 194 ALA B CB 1 ATOM 4540 N N . MET B 1 197 ? 214.931 58.449 24.445 1.00 50.17 ? 195 MET B N 1 ATOM 4541 C CA . MET B 1 197 ? 215.496 59.069 23.245 1.00 51.35 ? 195 MET B CA 1 ATOM 4542 C C . MET B 1 197 ? 216.688 59.935 23.553 1.00 56.71 ? 195 MET B C 1 ATOM 4543 O O . MET B 1 197 ? 217.699 59.819 22.860 1.00 56.58 ? 195 MET B O 1 ATOM 4544 C CB . MET B 1 197 ? 214.452 59.866 22.460 1.00 54.03 ? 195 MET B CB 1 ATOM 4545 C CG . MET B 1 197 ? 213.537 59.002 21.645 1.00 58.20 ? 195 MET B CG 1 ATOM 4546 S SD . MET B 1 197 ? 212.072 59.936 21.193 1.00 63.32 ? 195 MET B SD 1 ATOM 4547 C CE . MET B 1 197 ? 212.529 60.468 19.560 1.00 60.07 ? 195 MET B CE 1 ATOM 4548 N N . ALA B 1 198 ? 216.580 60.784 24.599 1.00 54.12 ? 196 ALA B N 1 ATOM 4549 C CA . ALA B 1 198 ? 217.654 61.668 25.058 1.00 54.04 ? 196 ALA B CA 1 ATOM 4550 C C . ALA B 1 198 ? 218.871 60.843 25.482 1.00 58.97 ? 196 ALA B C 1 ATOM 4551 O O . ALA B 1 198 ? 219.984 61.174 25.067 1.00 58.76 ? 196 ALA B O 1 ATOM 4552 C CB . ALA B 1 198 ? 217.171 62.524 26.213 1.00 54.56 ? 196 ALA B CB 1 ATOM 4553 N N . GLU B 1 199 ? 218.643 59.734 26.242 1.00 55.67 ? 197 GLU B N 1 ATOM 4554 C CA . GLU B 1 199 ? 219.678 58.807 26.712 1.00 56.05 ? 197 GLU B CA 1 ATOM 4555 C C . GLU B 1 199 ? 220.486 58.153 25.570 1.00 62.85 ? 197 GLU B C 1 ATOM 4556 O O . GLU B 1 199 ? 221.693 57.942 25.728 1.00 63.06 ? 197 GLU B O 1 ATOM 4557 C CB . GLU B 1 199 ? 219.092 57.751 27.651 1.00 57.04 ? 197 GLU B CB 1 ATOM 4558 C CG . GLU B 1 199 ? 218.734 58.324 29.012 1.00 66.84 ? 197 GLU B CG 1 ATOM 4559 C CD . GLU B 1 199 ? 218.315 57.340 30.089 1.00 95.04 ? 197 GLU B CD 1 ATOM 4560 O OE1 . GLU B 1 199 ? 217.584 57.764 31.013 1.00 93.02 ? 197 GLU B OE1 1 ATOM 4561 O OE2 . GLU B 1 199 ? 218.737 56.161 30.035 1.00 94.87 ? 197 GLU B OE2 1 ATOM 4562 N N . ILE B 1 200 ? 219.830 57.862 24.421 1.00 59.70 ? 198 ILE B N 1 ATOM 4563 C CA . ILE B 1 200 ? 220.468 57.280 23.235 1.00 59.47 ? 198 ILE B CA 1 ATOM 4564 C C . ILE B 1 200 ? 221.456 58.287 22.647 1.00 65.34 ? 198 ILE B C 1 ATOM 4565 O O . ILE B 1 200 ? 222.587 57.919 22.332 1.00 65.75 ? 198 ILE B O 1 ATOM 4566 C CB . ILE B 1 200 ? 219.433 56.797 22.174 1.00 61.83 ? 198 ILE B CB 1 ATOM 4567 C CG1 . ILE B 1 200 ? 218.541 55.674 22.735 1.00 61.78 ? 198 ILE B CG1 1 ATOM 4568 C CG2 . ILE B 1 200 ? 220.135 56.344 20.876 1.00 62.04 ? 198 ILE B CG2 1 ATOM 4569 C CD1 . ILE B 1 200 ? 217.346 55.328 21.881 1.00 64.89 ? 198 ILE B CD1 1 ATOM 4570 N N . LEU B 1 201 ? 221.020 59.549 22.492 1.00 62.42 ? 199 LEU B N 1 ATOM 4571 C CA . LEU B 1 201 ? 221.841 60.621 21.947 1.00 62.39 ? 199 LEU B CA 1 ATOM 4572 C C . LEU B 1 201 ? 223.090 60.758 22.790 1.00 69.52 ? 199 LEU B C 1 ATOM 4573 O O . LEU B 1 201 ? 224.196 60.745 22.239 1.00 69.45 ? 199 LEU B O 1 ATOM 4574 C CB . LEU B 1 201 ? 221.075 61.953 21.935 1.00 61.93 ? 199 LEU B CB 1 ATOM 4575 C CG . LEU B 1 201 ? 219.894 62.127 20.990 1.00 65.57 ? 199 LEU B CG 1 ATOM 4576 C CD1 . LEU B 1 201 ? 219.482 63.554 20.978 1.00 65.55 ? 199 LEU B CD1 1 ATOM 4577 C CD2 . LEU B 1 201 ? 220.245 61.760 19.566 1.00 67.05 ? 199 LEU B CD2 1 ATOM 4578 N N . ARG B 1 202 ? 222.903 60.819 24.135 1.00 67.82 ? 200 ARG B N 1 ATOM 4579 C CA . ARG B 1 202 ? 223.955 60.915 25.150 1.00 67.94 ? 200 ARG B CA 1 ATOM 4580 C C . ARG B 1 202 ? 225.004 59.808 25.010 1.00 70.40 ? 200 ARG B C 1 ATOM 4581 O O . ARG B 1 202 ? 226.197 60.116 24.936 1.00 70.70 ? 200 ARG B O 1 ATOM 4582 C CB . ARG B 1 202 ? 223.356 60.936 26.578 1.00 68.45 ? 200 ARG B CB 1 ATOM 4583 C CG . ARG B 1 202 ? 224.346 61.269 27.707 1.00 78.08 ? 200 ARG B CG 1 ATOM 4584 C CD . ARG B 1 202 ? 224.972 62.660 27.589 1.00 87.76 ? 200 ARG B CD 1 ATOM 4585 N NE . ARG B 1 202 ? 226.215 62.617 26.814 1.00 94.10 ? 200 ARG B NE 1 ATOM 4586 C CZ . ARG B 1 202 ? 226.882 63.681 26.381 1.00 102.74 ? 200 ARG B CZ 1 ATOM 4587 N NH1 . ARG B 1 202 ? 226.434 64.904 26.637 1.00 88.70 ? 200 ARG B NH1 1 ATOM 4588 N NH2 . ARG B 1 202 ? 228.001 63.532 25.686 1.00 85.86 ? 200 ARG B NH2 1 ATOM 4589 N N . PHE B 1 203 ? 224.557 58.544 24.943 1.00 64.91 ? 201 PHE B N 1 ATOM 4590 C CA . PHE B 1 203 ? 225.422 57.380 24.799 1.00 64.78 ? 201 PHE B CA 1 ATOM 4591 C C . PHE B 1 203 ? 226.342 57.486 23.584 1.00 72.94 ? 201 PHE B C 1 ATOM 4592 O O . PHE B 1 203 ? 227.542 57.291 23.729 1.00 73.96 ? 201 PHE B O 1 ATOM 4593 C CB . PHE B 1 203 ? 224.589 56.102 24.735 1.00 65.82 ? 201 PHE B CB 1 ATOM 4594 C CG . PHE B 1 203 ? 225.389 54.863 24.448 1.00 66.73 ? 201 PHE B CG 1 ATOM 4595 C CD1 . PHE B 1 203 ? 225.947 54.123 25.484 1.00 69.60 ? 201 PHE B CD1 1 ATOM 4596 C CD2 . PHE B 1 203 ? 225.568 54.419 23.141 1.00 68.10 ? 201 PHE B CD2 1 ATOM 4597 C CE1 . PHE B 1 203 ? 226.685 52.967 25.217 1.00 70.39 ? 201 PHE B CE1 1 ATOM 4598 C CE2 . PHE B 1 203 ? 226.318 53.277 22.871 1.00 70.95 ? 201 PHE B CE2 1 ATOM 4599 C CZ . PHE B 1 203 ? 226.865 52.552 23.911 1.00 69.40 ? 201 PHE B CZ 1 ATOM 4600 N N . PHE B 1 204 ? 225.789 57.785 22.398 1.00 71.14 ? 202 PHE B N 1 ATOM 4601 C CA . PHE B 1 204 ? 226.563 57.919 21.170 1.00 71.93 ? 202 PHE B CA 1 ATOM 4602 C C . PHE B 1 204 ? 227.271 59.271 21.072 1.00 78.77 ? 202 PHE B C 1 ATOM 4603 O O . PHE B 1 204 ? 227.942 59.539 20.068 1.00 79.07 ? 202 PHE B O 1 ATOM 4604 C CB . PHE B 1 204 ? 225.674 57.679 19.949 1.00 74.03 ? 202 PHE B CB 1 ATOM 4605 C CG . PHE B 1 204 ? 225.192 56.258 19.824 1.00 76.56 ? 202 PHE B CG 1 ATOM 4606 C CD1 . PHE B 1 204 ? 226.049 55.250 19.395 1.00 80.24 ? 202 PHE B CD1 1 ATOM 4607 C CD2 . PHE B 1 204 ? 223.878 55.924 20.129 1.00 79.61 ? 202 PHE B CD2 1 ATOM 4608 C CE1 . PHE B 1 204 ? 225.605 53.925 19.296 1.00 81.41 ? 202 PHE B CE1 1 ATOM 4609 C CE2 . PHE B 1 204 ? 223.431 54.600 20.021 1.00 82.61 ? 202 PHE B CE2 1 ATOM 4610 C CZ . PHE B 1 204 ? 224.296 53.611 19.603 1.00 80.67 ? 202 PHE B CZ 1 ATOM 4611 N N . ASN B 1 205 ? 227.138 60.113 22.125 1.00 76.23 ? 203 ASN B N 1 ATOM 4612 C CA . ASN B 1 205 ? 227.734 61.446 22.229 1.00 76.38 ? 203 ASN B CA 1 ATOM 4613 C C . ASN B 1 205 ? 227.272 62.348 21.071 1.00 79.73 ? 203 ASN B C 1 ATOM 4614 O O . ASN B 1 205 ? 228.083 62.884 20.305 1.00 79.43 ? 203 ASN B O 1 ATOM 4615 C CB . ASN B 1 205 ? 229.277 61.371 22.386 1.00 80.39 ? 203 ASN B CB 1 ATOM 4616 C CG . ASN B 1 205 ? 229.757 60.620 23.614 1.00 111.92 ? 203 ASN B CG 1 ATOM 4617 O OD1 . ASN B 1 205 ? 229.301 60.874 24.740 1.00 105.58 ? 203 ASN B OD1 1 ATOM 4618 N ND2 . ASN B 1 205 ? 230.703 59.685 23.414 1.00 110.14 ? 203 ASN B ND2 1 ATOM 4619 N N . TRP B 1 206 ? 225.944 62.472 20.929 1.00 75.93 ? 204 TRP B N 1 ATOM 4620 C CA . TRP B 1 206 ? 225.322 63.292 19.892 1.00 75.51 ? 204 TRP B CA 1 ATOM 4621 C C . TRP B 1 206 ? 224.816 64.581 20.509 1.00 77.79 ? 204 TRP B C 1 ATOM 4622 O O . TRP B 1 206 ? 223.650 64.708 20.857 1.00 77.46 ? 204 TRP B O 1 ATOM 4623 C CB . TRP B 1 206 ? 224.249 62.502 19.132 1.00 74.33 ? 204 TRP B CB 1 ATOM 4624 C CG . TRP B 1 206 ? 224.808 61.358 18.337 1.00 75.43 ? 204 TRP B CG 1 ATOM 4625 C CD1 . TRP B 1 206 ? 226.107 61.174 17.964 1.00 78.43 ? 204 TRP B CD1 1 ATOM 4626 C CD2 . TRP B 1 206 ? 224.073 60.260 17.788 1.00 75.36 ? 204 TRP B CD2 1 ATOM 4627 N NE1 . TRP B 1 206 ? 226.231 60.015 17.236 1.00 78.06 ? 204 TRP B NE1 1 ATOM 4628 C CE2 . TRP B 1 206 ? 224.996 59.440 17.100 1.00 79.41 ? 204 TRP B CE2 1 ATOM 4629 C CE3 . TRP B 1 206 ? 222.720 59.884 17.807 1.00 76.64 ? 204 TRP B CE3 1 ATOM 4630 C CZ2 . TRP B 1 206 ? 224.613 58.258 16.456 1.00 78.69 ? 204 TRP B CZ2 1 ATOM 4631 C CZ3 . TRP B 1 206 ? 222.339 58.720 17.156 1.00 78.10 ? 204 TRP B CZ3 1 ATOM 4632 C CH2 . TRP B 1 206 ? 223.277 57.926 16.486 1.00 78.73 ? 204 TRP B CH2 1 ATOM 4633 N N . THR B 1 207 ? 225.747 65.510 20.689 1.00 73.77 ? 205 THR B N 1 ATOM 4634 C CA . THR B 1 207 ? 225.616 66.814 21.335 1.00 73.22 ? 205 THR B CA 1 ATOM 4635 C C . THR B 1 207 ? 224.820 67.840 20.511 1.00 74.46 ? 205 THR B C 1 ATOM 4636 O O . THR B 1 207 ? 224.118 68.667 21.098 1.00 73.06 ? 205 THR B O 1 ATOM 4637 C CB . THR B 1 207 ? 227.031 67.342 21.689 1.00 85.38 ? 205 THR B CB 1 ATOM 4638 O OG1 . THR B 1 207 ? 227.839 67.458 20.507 1.00 84.06 ? 205 THR B OG1 1 ATOM 4639 C CG2 . THR B 1 207 ? 227.740 66.485 22.726 1.00 86.11 ? 205 THR B CG2 1 ATOM 4640 N N . TYR B 1 208 ? 224.976 67.830 19.167 1.00 70.06 ? 206 TYR B N 1 ATOM 4641 C CA . TYR B 1 208 ? 224.291 68.781 18.283 1.00 69.03 ? 206 TYR B CA 1 ATOM 4642 C C . TYR B 1 208 ? 223.324 68.051 17.394 1.00 71.14 ? 206 TYR B C 1 ATOM 4643 O O . TYR B 1 208 ? 223.736 67.290 16.511 1.00 70.88 ? 206 TYR B O 1 ATOM 4644 C CB . TYR B 1 208 ? 225.281 69.633 17.472 1.00 70.16 ? 206 TYR B CB 1 ATOM 4645 C CG . TYR B 1 208 ? 224.763 71.007 17.089 1.00 71.90 ? 206 TYR B CG 1 ATOM 4646 C CD1 . TYR B 1 208 ? 224.303 71.897 18.060 1.00 73.69 ? 206 TYR B CD1 1 ATOM 4647 C CD2 . TYR B 1 208 ? 224.824 71.455 15.769 1.00 72.51 ? 206 TYR B CD2 1 ATOM 4648 C CE1 . TYR B 1 208 ? 223.860 73.175 17.719 1.00 74.22 ? 206 TYR B CE1 1 ATOM 4649 C CE2 . TYR B 1 208 ? 224.396 72.737 15.418 1.00 73.17 ? 206 TYR B CE2 1 ATOM 4650 C CZ . TYR B 1 208 ? 223.916 73.593 16.398 1.00 80.28 ? 206 TYR B CZ 1 ATOM 4651 O OH . TYR B 1 208 ? 223.479 74.853 16.069 1.00 82.02 ? 206 TYR B OH 1 ATOM 4652 N N . VAL B 1 209 ? 222.018 68.245 17.678 1.00 66.00 ? 207 VAL B N 1 ATOM 4653 C CA . VAL B 1 209 ? 220.892 67.584 17.006 1.00 63.94 ? 207 VAL B CA 1 ATOM 4654 C C . VAL B 1 209 ? 219.811 68.575 16.613 1.00 67.20 ? 207 VAL B C 1 ATOM 4655 O O . VAL B 1 209 ? 219.678 69.629 17.232 1.00 67.39 ? 207 VAL B O 1 ATOM 4656 C CB . VAL B 1 209 ? 220.270 66.464 17.897 1.00 65.75 ? 207 VAL B CB 1 ATOM 4657 C CG1 . VAL B 1 209 ? 221.234 65.309 18.106 1.00 65.31 ? 207 VAL B CG1 1 ATOM 4658 C CG2 . VAL B 1 209 ? 219.779 67.008 19.235 1.00 64.96 ? 207 VAL B CG2 1 ATOM 4659 N N . SER B 1 210 ? 218.988 68.191 15.641 1.00 61.84 ? 208 SER B N 1 ATOM 4660 C CA . SER B 1 210 ? 217.808 68.952 15.263 1.00 60.35 ? 208 SER B CA 1 ATOM 4661 C C . SER B 1 210 ? 216.551 68.175 15.681 1.00 59.31 ? 208 SER B C 1 ATOM 4662 O O . SER B 1 210 ? 216.639 66.975 15.985 1.00 58.85 ? 208 SER B O 1 ATOM 4663 C CB . SER B 1 210 ? 217.802 69.234 13.769 1.00 64.51 ? 208 SER B CB 1 ATOM 4664 O OG . SER B 1 210 ? 218.909 70.075 13.509 1.00 76.07 ? 208 SER B OG 1 ATOM 4665 N N . THR B 1 211 ? 215.398 68.861 15.755 1.00 51.25 ? 209 THR B N 1 ATOM 4666 C CA . THR B 1 211 ? 214.157 68.188 16.108 1.00 49.11 ? 209 THR B CA 1 ATOM 4667 C C . THR B 1 211 ? 213.088 68.479 15.085 1.00 50.69 ? 209 THR B C 1 ATOM 4668 O O . THR B 1 211 ? 213.037 69.580 14.513 1.00 49.05 ? 209 THR B O 1 ATOM 4669 C CB . THR B 1 211 ? 213.647 68.524 17.525 1.00 51.94 ? 209 THR B CB 1 ATOM 4670 O OG1 . THR B 1 211 ? 213.152 69.858 17.563 1.00 54.52 ? 209 THR B OG1 1 ATOM 4671 C CG2 . THR B 1 211 ? 214.675 68.275 18.636 1.00 44.63 ? 209 THR B CG2 1 ATOM 4672 N N . VAL B 1 212 ? 212.230 67.469 14.847 1.00 45.56 ? 210 VAL B N 1 ATOM 4673 C CA . VAL B 1 212 ? 211.044 67.580 13.987 1.00 43.19 ? 210 VAL B CA 1 ATOM 4674 C C . VAL B 1 212 ? 209.870 67.012 14.790 1.00 41.61 ? 210 VAL B C 1 ATOM 4675 O O . VAL B 1 212 ? 209.962 65.901 15.318 1.00 41.66 ? 210 VAL B O 1 ATOM 4676 C CB . VAL B 1 212 ? 211.182 66.992 12.548 1.00 45.64 ? 210 VAL B CB 1 ATOM 4677 C CG1 . VAL B 1 212 ? 209.891 67.162 11.760 1.00 45.03 ? 210 VAL B CG1 1 ATOM 4678 C CG2 . VAL B 1 212 ? 212.336 67.645 11.786 1.00 45.02 ? 210 VAL B CG2 1 ATOM 4679 N N . ALA B 1 213 ? 208.824 67.813 14.974 1.00 33.70 ? 211 ALA B N 1 ATOM 4680 C CA . ALA B 1 213 ? 207.657 67.387 15.735 1.00 32.54 ? 211 ALA B CA 1 ATOM 4681 C C . ALA B 1 213 ? 206.391 67.603 14.961 1.00 36.50 ? 211 ALA B C 1 ATOM 4682 O O . ALA B 1 213 ? 206.280 68.559 14.189 1.00 34.40 ? 211 ALA B O 1 ATOM 4683 C CB . ALA B 1 213 ? 207.579 68.116 17.066 1.00 32.89 ? 211 ALA B CB 1 ATOM 4684 N N . SER B 1 214 ? 205.411 66.716 15.180 1.00 34.24 ? 212 SER B N 1 ATOM 4685 C CA . SER B 1 214 ? 204.121 66.862 14.527 1.00 33.16 ? 212 SER B CA 1 ATOM 4686 C C . SER B 1 214 ? 203.272 67.802 15.332 1.00 36.69 ? 212 SER B C 1 ATOM 4687 O O . SER B 1 214 ? 203.379 67.854 16.564 1.00 34.54 ? 212 SER B O 1 ATOM 4688 C CB . SER B 1 214 ? 203.436 65.512 14.409 1.00 34.57 ? 212 SER B CB 1 ATOM 4689 O OG . SER B 1 214 ? 204.100 64.747 13.421 1.00 38.92 ? 212 SER B OG 1 ATOM 4690 N N . GLU B 1 215 ? 202.432 68.564 14.642 1.00 36.10 ? 213 GLU B N 1 ATOM 4691 C CA . GLU B 1 215 ? 201.477 69.446 15.314 1.00 37.08 ? 213 GLU B CA 1 ATOM 4692 C C . GLU B 1 215 ? 200.520 68.550 16.110 1.00 41.78 ? 213 GLU B C 1 ATOM 4693 O O . GLU B 1 215 ? 200.114 67.493 15.604 1.00 43.56 ? 213 GLU B O 1 ATOM 4694 C CB . GLU B 1 215 ? 200.677 70.265 14.298 1.00 38.76 ? 213 GLU B CB 1 ATOM 4695 C CG . GLU B 1 215 ? 201.267 71.652 14.086 1.00 60.20 ? 213 GLU B CG 1 ATOM 4696 C CD . GLU B 1 215 ? 200.420 72.637 13.296 1.00 95.80 ? 213 GLU B CD 1 ATOM 4697 O OE1 . GLU B 1 215 ? 199.183 72.680 13.503 1.00 92.29 ? 213 GLU B OE1 1 ATOM 4698 O OE2 . GLU B 1 215 ? 201.012 73.411 12.507 1.00 92.74 ? 213 GLU B OE2 1 ATOM 4699 N N . GLY B 1 216 ? 200.259 68.922 17.360 1.00 35.09 ? 214 GLY B N 1 ATOM 4700 C CA . GLY B 1 216 ? 199.325 68.207 18.200 1.00 33.72 ? 214 GLY B CA 1 ATOM 4701 C C . GLY B 1 216 ? 199.796 67.840 19.576 1.00 39.65 ? 214 GLY B C 1 ATOM 4702 O O . GLY B 1 216 ? 200.892 68.192 20.011 1.00 38.41 ? 214 GLY B O 1 ATOM 4703 N N . ASP B 1 217 ? 198.956 67.075 20.256 1.00 38.78 ? 215 ASP B N 1 ATOM 4704 C CA . ASP B 1 217 ? 199.235 66.672 21.608 1.00 38.55 ? 215 ASP B CA 1 ATOM 4705 C C . ASP B 1 217 ? 200.275 65.599 21.723 1.00 40.88 ? 215 ASP B C 1 ATOM 4706 O O . ASP B 1 217 ? 200.805 65.428 22.808 1.00 42.33 ? 215 ASP B O 1 ATOM 4707 C CB . ASP B 1 217 ? 197.951 66.293 22.307 1.00 41.20 ? 215 ASP B CB 1 ATOM 4708 C CG . ASP B 1 217 ? 197.101 67.519 22.598 1.00 62.49 ? 215 ASP B CG 1 ATOM 4709 O OD1 . ASP B 1 217 ? 197.666 68.535 23.102 1.00 61.62 ? 215 ASP B OD1 1 ATOM 4710 O OD2 . ASP B 1 217 ? 195.874 67.480 22.297 1.00 74.70 ? 215 ASP B OD2 1 ATOM 4711 N N . TYR B 1 218 ? 200.598 64.892 20.635 1.00 34.04 ? 216 TYR B N 1 ATOM 4712 C CA . TYR B 1 218 ? 201.630 63.865 20.686 1.00 32.37 ? 216 TYR B CA 1 ATOM 4713 C C . TYR B 1 218 ? 203.007 64.463 20.351 1.00 37.45 ? 216 TYR B C 1 ATOM 4714 O O . TYR B 1 218 ? 203.949 64.346 21.143 1.00 36.66 ? 216 TYR B O 1 ATOM 4715 C CB . TYR B 1 218 ? 201.268 62.707 19.747 1.00 31.27 ? 216 TYR B CB 1 ATOM 4716 C CG . TYR B 1 218 ? 202.398 61.740 19.501 1.00 29.20 ? 216 TYR B CG 1 ATOM 4717 C CD1 . TYR B 1 218 ? 202.723 60.763 20.438 1.00 30.77 ? 216 TYR B CD1 1 ATOM 4718 C CD2 . TYR B 1 218 ? 203.132 61.783 18.320 1.00 28.64 ? 216 TYR B CD2 1 ATOM 4719 C CE1 . TYR B 1 218 ? 203.736 59.839 20.192 1.00 30.34 ? 216 TYR B CE1 1 ATOM 4720 C CE2 . TYR B 1 218 ? 204.138 60.859 18.059 1.00 28.46 ? 216 TYR B CE2 1 ATOM 4721 C CZ . TYR B 1 218 ? 204.440 59.895 19.001 1.00 31.31 ? 216 TYR B CZ 1 ATOM 4722 O OH . TYR B 1 218 ? 205.455 59.022 18.751 1.00 29.69 ? 216 TYR B OH 1 ATOM 4723 N N . GLY B 1 219 ? 203.093 65.085 19.177 1.00 34.51 ? 217 GLY B N 1 ATOM 4724 C CA . GLY B 1 219 ? 204.305 65.712 18.671 1.00 34.68 ? 217 GLY B CA 1 ATOM 4725 C C . GLY B 1 219 ? 204.842 66.838 19.521 1.00 38.62 ? 217 GLY B C 1 ATOM 4726 O O . GLY B 1 219 ? 206.002 66.790 19.963 1.00 38.65 ? 217 GLY B O 1 ATOM 4727 N N . GLU B 1 220 ? 203.994 67.851 19.759 1.00 34.55 ? 218 GLU B N 1 ATOM 4728 C CA . GLU B 1 220 ? 204.379 69.029 20.527 1.00 35.00 ? 218 GLU B CA 1 ATOM 4729 C C . GLU B 1 220 ? 204.731 68.707 21.983 1.00 42.49 ? 218 GLU B C 1 ATOM 4730 O O . GLU B 1 220 ? 205.781 69.140 22.442 1.00 43.75 ? 218 GLU B O 1 ATOM 4731 C CB . GLU B 1 220 ? 203.332 70.152 20.424 1.00 36.26 ? 218 GLU B CB 1 ATOM 4732 C CG . GLU B 1 220 ? 203.105 70.680 19.006 1.00 48.55 ? 218 GLU B CG 1 ATOM 4733 C CD . GLU B 1 220 ? 202.025 71.737 18.819 1.00 81.58 ? 218 GLU B CD 1 ATOM 4734 O OE1 . GLU B 1 220 ? 202.149 72.838 19.406 1.00 97.54 ? 218 GLU B OE1 1 ATOM 4735 O OE2 . GLU B 1 220 ? 201.084 71.486 18.031 1.00 68.11 ? 218 GLU B OE2 1 ATOM 4736 N N . THR B 1 221 ? 203.916 67.907 22.687 1.00 40.18 ? 219 THR B N 1 ATOM 4737 C CA . THR B 1 221 ? 204.183 67.596 24.094 1.00 40.52 ? 219 THR B CA 1 ATOM 4738 C C . THR B 1 221 ? 205.399 66.660 24.246 1.00 44.73 ? 219 THR B C 1 ATOM 4739 O O . THR B 1 221 ? 206.221 66.877 25.135 1.00 45.23 ? 219 THR B O 1 ATOM 4740 C CB . THR B 1 221 ? 202.919 67.101 24.832 1.00 47.84 ? 219 THR B CB 1 ATOM 4741 O OG1 . THR B 1 221 ? 202.729 65.713 24.596 1.00 52.53 ? 219 THR B OG1 1 ATOM 4742 C CG2 . THR B 1 221 ? 201.661 67.890 24.464 1.00 41.49 ? 219 THR B CG2 1 ATOM 4743 N N . GLY B 1 222 ? 205.525 65.688 23.350 1.00 39.76 ? 220 GLY B N 1 ATOM 4744 C CA . GLY B 1 222 ? 206.642 64.755 23.353 1.00 39.22 ? 220 GLY B CA 1 ATOM 4745 C C . GLY B 1 222 ? 207.993 65.387 23.064 1.00 43.35 ? 220 GLY B C 1 ATOM 4746 O O . GLY B 1 222 ? 208.979 65.053 23.743 1.00 41.55 ? 220 GLY B O 1 ATOM 4747 N N . ILE B 1 223 ? 208.059 66.288 22.096 1.00 40.69 ? 221 ILE B N 1 ATOM 4748 C CA . ILE B 1 223 ? 209.312 66.942 21.772 1.00 41.51 ? 221 ILE B CA 1 ATOM 4749 C C . ILE B 1 223 ? 209.695 68.002 22.784 1.00 47.60 ? 221 ILE B C 1 ATOM 4750 O O . ILE B 1 223 ? 210.833 68.218 23.054 1.00 48.54 ? 221 ILE B O 1 ATOM 4751 C CB . ILE B 1 223 ? 209.354 67.441 20.313 1.00 45.00 ? 221 ILE B CB 1 ATOM 4752 C CG1 . ILE B 1 223 ? 210.718 67.216 19.705 1.00 45.45 ? 221 ILE B CG1 1 ATOM 4753 C CG2 . ILE B 1 223 ? 208.995 68.895 20.171 1.00 44.98 ? 221 ILE B CG2 1 ATOM 4754 C CD1 . ILE B 1 223 ? 211.194 65.808 19.815 1.00 50.21 ? 221 ILE B CD1 1 ATOM 4755 N N . GLU B 1 224 ? 208.729 68.649 23.371 1.00 44.45 ? 222 GLU B N 1 ATOM 4756 C CA . GLU B 1 224 ? 209.008 69.546 24.485 1.00 45.47 ? 222 GLU B CA 1 ATOM 4757 C C . GLU B 1 224 ? 209.572 68.744 25.680 1.00 48.82 ? 222 GLU B C 1 ATOM 4758 O O . GLU B 1 224 ? 210.444 69.256 26.374 1.00 51.36 ? 222 GLU B O 1 ATOM 4759 C CB . GLU B 1 224 ? 207.745 70.365 24.848 1.00 47.66 ? 222 GLU B CB 1 ATOM 4760 C CG . GLU B 1 224 ? 207.541 70.763 26.308 1.00 61.61 ? 222 GLU B CG 1 ATOM 4761 C CD . GLU B 1 224 ? 206.189 71.407 26.570 1.00 95.35 ? 222 GLU B CD 1 ATOM 4762 O OE1 . GLU B 1 224 ? 205.166 70.682 26.580 1.00 93.28 ? 222 GLU B OE1 1 ATOM 4763 O OE2 . GLU B 1 224 ? 206.151 72.650 26.721 1.00 95.29 ? 222 GLU B OE2 1 ATOM 4764 N N . ALA B 1 225 ? 209.110 67.501 25.899 1.00 42.55 ? 223 ALA B N 1 ATOM 4765 C CA . ALA B 1 225 ? 209.628 66.665 26.986 1.00 42.58 ? 223 ALA B CA 1 ATOM 4766 C C . ALA B 1 225 ? 211.036 66.158 26.677 1.00 48.52 ? 223 ALA B C 1 ATOM 4767 O O . ALA B 1 225 ? 211.843 66.033 27.595 1.00 48.90 ? 223 ALA B O 1 ATOM 4768 C CB . ALA B 1 225 ? 208.696 65.500 27.278 1.00 43.14 ? 223 ALA B CB 1 ATOM 4769 N N . PHE B 1 226 ? 211.335 65.862 25.398 1.00 46.20 ? 224 PHE B N 1 ATOM 4770 C CA . PHE B 1 226 ? 212.673 65.439 24.967 1.00 46.48 ? 224 PHE B CA 1 ATOM 4771 C C . PHE B 1 226 ? 213.631 66.631 25.141 1.00 50.45 ? 224 PHE B C 1 ATOM 4772 O O . PHE B 1 226 ? 214.759 66.447 25.579 1.00 48.66 ? 224 PHE B O 1 ATOM 4773 C CB . PHE B 1 226 ? 212.666 64.984 23.493 1.00 48.43 ? 224 PHE B CB 1 ATOM 4774 C CG . PHE B 1 226 ? 214.014 65.118 22.824 1.00 50.92 ? 224 PHE B CG 1 ATOM 4775 C CD1 . PHE B 1 226 ? 214.957 64.099 22.913 1.00 55.18 ? 224 PHE B CD1 1 ATOM 4776 C CD2 . PHE B 1 226 ? 214.359 66.284 22.140 1.00 53.80 ? 224 PHE B CD2 1 ATOM 4777 C CE1 . PHE B 1 226 ? 216.208 64.225 22.298 1.00 56.16 ? 224 PHE B CE1 1 ATOM 4778 C CE2 . PHE B 1 226 ? 215.613 66.416 21.537 1.00 56.92 ? 224 PHE B CE2 1 ATOM 4779 C CZ . PHE B 1 226 ? 216.526 65.384 21.613 1.00 55.34 ? 224 PHE B CZ 1 ATOM 4780 N N . GLU B 1 227 ? 213.166 67.843 24.771 1.00 48.57 ? 225 GLU B N 1 ATOM 4781 C CA . GLU B 1 227 ? 213.919 69.077 24.874 1.00 49.16 ? 225 GLU B CA 1 ATOM 4782 C C . GLU B 1 227 ? 214.383 69.261 26.313 1.00 57.65 ? 225 GLU B C 1 ATOM 4783 O O . GLU B 1 227 ? 215.576 69.507 26.511 1.00 59.12 ? 225 GLU B O 1 ATOM 4784 C CB . GLU B 1 227 ? 213.118 70.266 24.334 1.00 50.13 ? 225 GLU B CB 1 ATOM 4785 C CG . GLU B 1 227 ? 213.296 70.460 22.831 1.00 56.60 ? 225 GLU B CG 1 ATOM 4786 C CD . GLU B 1 227 ? 212.275 71.315 22.085 1.00 81.32 ? 225 GLU B CD 1 ATOM 4787 O OE1 . GLU B 1 227 ? 211.417 71.958 22.739 1.00 74.77 ? 225 GLU B OE1 1 ATOM 4788 O OE2 . GLU B 1 227 ? 212.339 71.338 20.832 1.00 69.72 ? 225 GLU B OE2 1 ATOM 4789 N N . LEU B 1 228 ? 213.487 69.027 27.310 1.00 55.37 ? 226 LEU B N 1 ATOM 4790 C CA . LEU B 1 228 ? 213.819 69.059 28.740 1.00 56.03 ? 226 LEU B CA 1 ATOM 4791 C C . LEU B 1 228 ? 214.934 68.062 29.045 1.00 58.05 ? 226 LEU B C 1 ATOM 4792 O O . LEU B 1 228 ? 215.921 68.416 29.684 1.00 57.80 ? 226 LEU B O 1 ATOM 4793 C CB . LEU B 1 228 ? 212.606 68.679 29.613 1.00 57.01 ? 226 LEU B CB 1 ATOM 4794 C CG . LEU B 1 228 ? 211.561 69.749 29.888 1.00 63.90 ? 226 LEU B CG 1 ATOM 4795 C CD1 . LEU B 1 228 ? 210.301 69.127 30.484 1.00 64.40 ? 226 LEU B CD1 1 ATOM 4796 C CD2 . LEU B 1 228 ? 212.105 70.856 30.816 1.00 67.55 ? 226 LEU B CD2 1 ATOM 4797 N N . GLU B 1 229 ? 214.772 66.825 28.575 1.00 53.79 ? 227 GLU B N 1 ATOM 4798 C CA . GLU B 1 229 ? 215.704 65.730 28.814 1.00 53.98 ? 227 GLU B CA 1 ATOM 4799 C C . GLU B 1 229 ? 217.073 65.909 28.109 1.00 60.68 ? 227 GLU B C 1 ATOM 4800 O O . GLU B 1 229 ? 218.089 65.420 28.616 1.00 59.92 ? 227 GLU B O 1 ATOM 4801 C CB . GLU B 1 229 ? 215.045 64.390 28.457 1.00 54.73 ? 227 GLU B CB 1 ATOM 4802 C CG . GLU B 1 229 ? 213.824 64.041 29.299 1.00 61.41 ? 227 GLU B CG 1 ATOM 4803 C CD . GLU B 1 229 ? 214.015 63.671 30.764 1.00 77.98 ? 227 GLU B CD 1 ATOM 4804 O OE1 . GLU B 1 229 ? 215.173 63.487 31.208 1.00 76.35 ? 227 GLU B OE1 1 ATOM 4805 O OE2 . GLU B 1 229 ? 212.987 63.555 31.470 1.00 61.55 ? 227 GLU B OE2 1 ATOM 4806 N N . ALA B 1 230 ? 217.093 66.636 26.966 1.00 58.49 ? 228 ALA B N 1 ATOM 4807 C CA . ALA B 1 230 ? 218.296 66.916 26.169 1.00 58.39 ? 228 ALA B CA 1 ATOM 4808 C C . ALA B 1 230 ? 219.165 67.952 26.875 1.00 63.25 ? 228 ALA B C 1 ATOM 4809 O O . ALA B 1 230 ? 220.388 67.794 26.910 1.00 63.55 ? 228 ALA B O 1 ATOM 4810 C CB . ALA B 1 230 ? 217.913 67.411 24.779 1.00 58.69 ? 228 ALA B CB 1 ATOM 4811 N N . ARG B 1 231 ? 218.524 69.009 27.432 1.00 58.83 ? 229 ARG B N 1 ATOM 4812 C CA . ARG B 1 231 ? 219.145 70.082 28.200 1.00 58.67 ? 229 ARG B CA 1 ATOM 4813 C C . ARG B 1 231 ? 219.981 69.431 29.333 1.00 63.55 ? 229 ARG B C 1 ATOM 4814 O O . ARG B 1 231 ? 221.213 69.537 29.341 1.00 63.04 ? 229 ARG B O 1 ATOM 4815 C CB . ARG B 1 231 ? 218.030 70.972 28.791 1.00 58.75 ? 229 ARG B CB 1 ATOM 4816 C CG . ARG B 1 231 ? 218.430 72.415 29.100 1.00 72.32 ? 229 ARG B CG 1 ATOM 4817 C CD . ARG B 1 231 ? 217.252 73.387 29.009 1.00 85.45 ? 229 ARG B CD 1 ATOM 4818 N NE . ARG B 1 231 ? 216.575 73.312 27.707 1.00 91.99 ? 229 ARG B NE 1 ATOM 4819 C CZ . ARG B 1 231 ? 215.326 72.886 27.523 1.00 90.63 ? 229 ARG B CZ 1 ATOM 4820 N NH1 . ARG B 1 231 ? 214.575 72.537 28.563 1.00 76.50 ? 229 ARG B NH1 1 ATOM 4821 N NH2 . ARG B 1 231 ? 214.814 72.821 26.300 1.00 57.05 ? 229 ARG B NH2 1 ATOM 4822 N N . ALA B 1 232 ? 219.295 68.655 30.200 1.00 60.06 ? 230 ALA B N 1 ATOM 4823 C CA . ALA B 1 232 ? 219.817 67.920 31.346 1.00 59.79 ? 230 ALA B CA 1 ATOM 4824 C C . ALA B 1 232 ? 220.907 66.881 31.013 1.00 64.26 ? 230 ALA B C 1 ATOM 4825 O O . ALA B 1 232 ? 221.451 66.257 31.932 1.00 65.22 ? 230 ALA B O 1 ATOM 4826 C CB . ALA B 1 232 ? 218.665 67.256 32.085 1.00 60.45 ? 230 ALA B CB 1 ATOM 4827 N N . ARG B 1 233 ? 221.219 66.684 29.723 1.00 59.79 ? 231 ARG B N 1 ATOM 4828 C CA . ARG B 1 233 ? 222.256 65.743 29.285 1.00 59.60 ? 231 ARG B CA 1 ATOM 4829 C C . ARG B 1 233 ? 223.287 66.454 28.404 1.00 64.86 ? 231 ARG B C 1 ATOM 4830 O O . ARG B 1 233 ? 223.997 65.804 27.634 1.00 64.81 ? 231 ARG B O 1 ATOM 4831 C CB . ARG B 1 233 ? 221.642 64.499 28.592 1.00 57.49 ? 231 ARG B CB 1 ATOM 4832 C CG . ARG B 1 233 ? 221.087 63.463 29.577 1.00 58.70 ? 231 ARG B CG 1 ATOM 4833 C CD . ARG B 1 233 ? 220.130 62.476 28.925 1.00 54.40 ? 231 ARG B CD 1 ATOM 4834 N NE . ARG B 1 233 ? 219.414 61.648 29.903 1.00 52.68 ? 231 ARG B NE 1 ATOM 4835 C CZ . ARG B 1 233 ? 218.319 62.024 30.560 1.00 69.42 ? 231 ARG B CZ 1 ATOM 4836 N NH1 . ARG B 1 233 ? 217.808 63.238 30.378 1.00 59.70 ? 231 ARG B NH1 1 ATOM 4837 N NH2 . ARG B 1 233 ? 217.750 61.206 31.435 1.00 56.19 ? 231 ARG B NH2 1 ATOM 4838 N N . ASN B 1 234 ? 223.370 67.799 28.538 1.00 62.07 ? 232 ASN B N 1 ATOM 4839 C CA . ASN B 1 234 ? 224.262 68.693 27.791 1.00 62.69 ? 232 ASN B CA 1 ATOM 4840 C C . ASN B 1 234 ? 224.164 68.468 26.249 1.00 67.38 ? 232 ASN B C 1 ATOM 4841 O O . ASN B 1 234 ? 225.174 68.484 25.532 1.00 67.08 ? 232 ASN B O 1 ATOM 4842 C CB . ASN B 1 234 ? 225.715 68.621 28.322 1.00 66.54 ? 232 ASN B CB 1 ATOM 4843 C CG . ASN B 1 234 ? 225.872 68.887 29.806 1.00 99.63 ? 232 ASN B CG 1 ATOM 4844 O OD1 . ASN B 1 234 ? 225.492 69.949 30.326 1.00 95.35 ? 232 ASN B OD1 1 ATOM 4845 N ND2 . ASN B 1 234 ? 226.473 67.932 30.518 1.00 91.85 ? 232 ASN B ND2 1 ATOM 4846 N N . ILE B 1 235 ? 222.921 68.237 25.764 1.00 63.30 ? 233 ILE B N 1 ATOM 4847 C CA . ILE B 1 235 ? 222.592 68.031 24.349 1.00 61.83 ? 233 ILE B CA 1 ATOM 4848 C C . ILE B 1 235 ? 221.882 69.309 23.927 1.00 63.88 ? 233 ILE B C 1 ATOM 4849 O O . ILE B 1 235 ? 221.020 69.791 24.665 1.00 62.37 ? 233 ILE B O 1 ATOM 4850 C CB . ILE B 1 235 ? 221.744 66.735 24.113 1.00 64.34 ? 233 ILE B CB 1 ATOM 4851 C CG1 . ILE B 1 235 ? 222.442 65.497 24.715 1.00 65.06 ? 233 ILE B CG1 1 ATOM 4852 C CG2 . ILE B 1 235 ? 221.451 66.522 22.627 1.00 63.76 ? 233 ILE B CG2 1 ATOM 4853 C CD1 . ILE B 1 235 ? 221.625 64.194 24.815 1.00 74.31 ? 233 ILE B CD1 1 ATOM 4854 N N . SER B 1 236 ? 222.303 69.899 22.787 1.00 60.53 ? 234 SER B N 1 ATOM 4855 C CA . SER B 1 236 ? 221.767 71.168 22.269 1.00 60.10 ? 234 SER B CA 1 ATOM 4856 C C . SER B 1 236 ? 221.031 71.018 20.942 1.00 62.07 ? 234 SER B C 1 ATOM 4857 O O . SER B 1 236 ? 221.453 70.250 20.068 1.00 62.00 ? 234 SER B O 1 ATOM 4858 C CB . SER B 1 236 ? 222.869 72.228 22.162 1.00 64.00 ? 234 SER B CB 1 ATOM 4859 O OG . SER B 1 236 ? 223.991 71.795 21.406 1.00 71.52 ? 234 SER B OG 1 ATOM 4860 N N . VAL B 1 237 ? 219.943 71.775 20.785 1.00 56.42 ? 235 VAL B N 1 ATOM 4861 C CA . VAL B 1 237 ? 219.148 71.706 19.566 1.00 55.60 ? 235 VAL B CA 1 ATOM 4862 C C . VAL B 1 237 ? 219.584 72.769 18.565 1.00 58.56 ? 235 VAL B C 1 ATOM 4863 O O . VAL B 1 237 ? 219.554 73.965 18.871 1.00 57.81 ? 235 VAL B O 1 ATOM 4864 C CB . VAL B 1 237 ? 217.606 71.715 19.819 1.00 59.18 ? 235 VAL B CB 1 ATOM 4865 C CG1 . VAL B 1 237 ? 216.830 71.376 18.543 1.00 58.74 ? 235 VAL B CG1 1 ATOM 4866 C CG2 . VAL B 1 237 ? 217.222 70.755 20.942 1.00 58.84 ? 235 VAL B CG2 1 ATOM 4867 N N . ALA B 1 238 ? 219.952 72.325 17.354 1.00 55.19 ? 236 ALA B N 1 ATOM 4868 C CA . ALA B 1 238 ? 220.316 73.191 16.239 1.00 55.35 ? 236 ALA B CA 1 ATOM 4869 C C . ALA B 1 238 ? 219.084 73.982 15.786 1.00 61.08 ? 236 ALA B C 1 ATOM 4870 O O . ALA B 1 238 ? 219.070 75.208 15.893 1.00 61.33 ? 236 ALA B O 1 ATOM 4871 C CB . ALA B 1 238 ? 220.838 72.357 15.090 1.00 55.88 ? 236 ALA B CB 1 ATOM 4872 N N . THR B 1 239 ? 218.041 73.266 15.319 1.00 58.25 ? 237 THR B N 1 ATOM 4873 C CA . THR B 1 239 ? 216.778 73.834 14.846 1.00 58.04 ? 237 THR B CA 1 ATOM 4874 C C . THR B 1 239 ? 215.608 72.903 15.233 1.00 62.23 ? 237 THR B C 1 ATOM 4875 O O . THR B 1 239 ? 215.763 71.677 15.307 1.00 61.39 ? 237 THR B O 1 ATOM 4876 C CB . THR B 1 239 ? 216.844 74.238 13.324 1.00 62.54 ? 237 THR B CB 1 ATOM 4877 O OG1 . THR B 1 239 ? 215.542 74.434 12.771 1.00 58.85 ? 237 THR B OG1 1 ATOM 4878 C CG2 . THR B 1 239 ? 217.609 73.251 12.456 1.00 60.26 ? 237 THR B CG2 1 ATOM 4879 N N . SER B 1 240 ? 214.450 73.522 15.531 1.00 58.51 ? 238 SER B N 1 ATOM 4880 C CA . SER B 1 240 ? 213.203 72.852 15.889 1.00 57.16 ? 238 SER B CA 1 ATOM 4881 C C . SER B 1 240 ? 212.205 73.119 14.783 1.00 58.21 ? 238 SER B C 1 ATOM 4882 O O . SER B 1 240 ? 211.867 74.271 14.519 1.00 58.44 ? 238 SER B O 1 ATOM 4883 C CB . SER B 1 240 ? 212.663 73.369 17.221 1.00 60.36 ? 238 SER B CB 1 ATOM 4884 O OG . SER B 1 240 ? 213.367 72.826 18.327 1.00 70.62 ? 238 SER B OG 1 ATOM 4885 N N . GLU B 1 241 ? 211.790 72.063 14.090 1.00 52.25 ? 239 GLU B N 1 ATOM 4886 C CA . GLU B 1 241 ? 210.804 72.168 13.020 1.00 50.45 ? 239 GLU B CA 1 ATOM 4887 C C . GLU B 1 241 ? 209.492 71.552 13.482 1.00 49.90 ? 239 GLU B C 1 ATOM 4888 O O . GLU B 1 241 ? 209.483 70.689 14.356 1.00 48.36 ? 239 GLU B O 1 ATOM 4889 C CB . GLU B 1 241 ? 211.305 71.506 11.713 1.00 51.66 ? 239 GLU B CB 1 ATOM 4890 C CG . GLU B 1 241 ? 212.464 72.223 11.042 1.00 60.46 ? 239 GLU B CG 1 ATOM 4891 C CD . GLU B 1 241 ? 212.205 73.656 10.609 1.00 89.21 ? 239 GLU B CD 1 ATOM 4892 O OE1 . GLU B 1 241 ? 211.221 73.903 9.872 1.00 75.60 ? 239 GLU B OE1 1 ATOM 4893 O OE2 . GLU B 1 241 ? 213.012 74.532 10.994 1.00 92.21 ? 239 GLU B OE2 1 ATOM 4894 N N . LYS B 1 242 ? 208.391 72.024 12.912 1.00 45.24 ? 240 LYS B N 1 ATOM 4895 C CA . LYS B 1 242 ? 207.048 71.532 13.196 1.00 44.31 ? 240 LYS B CA 1 ATOM 4896 C C . LYS B 1 242 ? 206.323 71.189 11.897 1.00 46.96 ? 240 LYS B C 1 ATOM 4897 O O . LYS B 1 242 ? 206.378 71.937 10.918 1.00 48.09 ? 240 LYS B O 1 ATOM 4898 C CB . LYS B 1 242 ? 206.238 72.506 14.071 1.00 45.61 ? 240 LYS B CB 1 ATOM 4899 N N . VAL B 1 243 ? 205.686 70.042 11.879 1.00 41.25 ? 241 VAL B N 1 ATOM 4900 C CA . VAL B 1 243 ? 204.938 69.577 10.725 1.00 40.98 ? 241 VAL B CA 1 ATOM 4901 C C . VAL B 1 243 ? 203.437 69.846 10.996 1.00 49.02 ? 241 VAL B C 1 ATOM 4902 O O . VAL B 1 243 ? 202.934 69.504 12.065 1.00 50.20 ? 241 VAL B O 1 ATOM 4903 C CB . VAL B 1 243 ? 205.236 68.072 10.475 1.00 42.70 ? 241 VAL B CB 1 ATOM 4904 C CG1 . VAL B 1 243 ? 204.273 67.486 9.458 1.00 42.06 ? 241 VAL B CG1 1 ATOM 4905 C CG2 . VAL B 1 243 ? 206.674 67.866 10.034 1.00 41.73 ? 241 VAL B CG2 1 ATOM 4906 N N . GLY B 1 244 ? 202.749 70.442 10.034 1.00 46.54 ? 242 GLY B N 1 ATOM 4907 C CA . GLY B 1 244 ? 201.330 70.740 10.171 1.00 47.13 ? 242 GLY B CA 1 ATOM 4908 C C . GLY B 1 244 ? 200.426 69.588 9.791 1.00 53.87 ? 242 GLY B C 1 ATOM 4909 O O . GLY B 1 244 ? 200.853 68.637 9.116 1.00 54.39 ? 242 GLY B O 1 ATOM 4910 N N . ARG B 1 245 ? 199.146 69.700 10.204 1.00 51.31 ? 243 ARG B N 1 ATOM 4911 C CA . ARG B 1 245 ? 198.072 68.723 9.943 1.00 51.09 ? 243 ARG B CA 1 ATOM 4912 C C . ARG B 1 245 ? 197.742 68.525 8.457 1.00 54.50 ? 243 ARG B C 1 ATOM 4913 O O . ARG B 1 245 ? 197.196 67.482 8.105 1.00 53.93 ? 243 ARG B O 1 ATOM 4914 C CB . ARG B 1 245 ? 196.790 69.114 10.707 1.00 50.56 ? 243 ARG B CB 1 ATOM 4915 N N . ALA B 1 246 ? 198.038 69.524 7.593 1.00 50.72 ? 244 ALA B N 1 ATOM 4916 C CA . ALA B 1 246 ? 197.693 69.436 6.174 1.00 50.35 ? 244 ALA B CA 1 ATOM 4917 C C . ALA B 1 246 ? 198.806 69.903 5.193 1.00 53.87 ? 244 ALA B C 1 ATOM 4918 O O . ALA B 1 246 ? 198.504 70.410 4.113 1.00 55.17 ? 244 ALA B O 1 ATOM 4919 C CB . ALA B 1 246 ? 196.388 70.180 5.915 1.00 50.83 ? 244 ALA B CB 1 ATOM 4920 N N . MET B 1 247 ? 200.074 69.658 5.523 1.00 47.61 ? 245 MET B N 1 ATOM 4921 C CA . MET B 1 247 ? 201.191 70.017 4.641 1.00 46.07 ? 245 MET B CA 1 ATOM 4922 C C . MET B 1 247 ? 201.200 69.230 3.333 1.00 47.16 ? 245 MET B C 1 ATOM 4923 O O . MET B 1 247 ? 200.588 68.162 3.249 1.00 45.88 ? 245 MET B O 1 ATOM 4924 C CB . MET B 1 247 ? 202.523 69.832 5.359 1.00 48.13 ? 245 MET B CB 1 ATOM 4925 C CG . MET B 1 247 ? 202.860 70.972 6.243 1.00 51.36 ? 245 MET B CG 1 ATOM 4926 S SD . MET B 1 247 ? 204.380 70.706 7.136 1.00 55.67 ? 245 MET B SD 1 ATOM 4927 C CE . MET B 1 247 ? 205.474 70.261 5.856 1.00 51.55 ? 245 MET B CE 1 ATOM 4928 N N . SER B 1 248 ? 201.887 69.782 2.311 1.00 41.89 ? 246 SER B N 1 ATOM 4929 C CA . SER B 1 248 ? 202.028 69.197 0.976 1.00 40.17 ? 246 SER B CA 1 ATOM 4930 C C . SER B 1 248 ? 203.440 68.608 0.791 1.00 43.11 ? 246 SER B C 1 ATOM 4931 O O . SER B 1 248 ? 204.320 68.824 1.649 1.00 42.67 ? 246 SER B O 1 ATOM 4932 C CB . SER B 1 248 ? 201.762 70.258 -0.092 1.00 41.97 ? 246 SER B CB 1 ATOM 4933 O OG . SER B 1 248 ? 202.835 71.181 -0.210 1.00 47.40 ? 246 SER B OG 1 ATOM 4934 N N . ARG B 1 249 ? 203.661 67.894 -0.344 1.00 37.55 ? 247 ARG B N 1 ATOM 4935 C CA . ARG B 1 249 ? 204.955 67.306 -0.669 1.00 37.57 ? 247 ARG B CA 1 ATOM 4936 C C . ARG B 1 249 ? 206.035 68.368 -0.802 1.00 39.88 ? 247 ARG B C 1 ATOM 4937 O O . ARG B 1 249 ? 207.110 68.184 -0.245 1.00 39.80 ? 247 ARG B O 1 ATOM 4938 C CB . ARG B 1 249 ? 204.891 66.431 -1.930 1.00 42.08 ? 247 ARG B CB 1 ATOM 4939 C CG . ARG B 1 249 ? 204.081 65.144 -1.779 1.00 56.29 ? 247 ARG B CG 1 ATOM 4940 C CD . ARG B 1 249 ? 203.705 64.577 -3.142 1.00 73.24 ? 247 ARG B CD 1 ATOM 4941 N NE . ARG B 1 249 ? 204.654 63.562 -3.610 1.00 90.11 ? 247 ARG B NE 1 ATOM 4942 C CZ . ARG B 1 249 ? 205.719 63.808 -4.371 1.00 110.34 ? 247 ARG B CZ 1 ATOM 4943 N NH1 . ARG B 1 249 ? 205.994 65.049 -4.764 1.00 97.89 ? 247 ARG B NH1 1 ATOM 4944 N NH2 . ARG B 1 249 ? 206.517 62.816 -4.744 1.00 100.18 ? 247 ARG B NH2 1 ATOM 4945 N N . ALA B 1 250 ? 205.741 69.508 -1.473 1.00 36.30 ? 248 ALA B N 1 ATOM 4946 C CA . ALA B 1 250 ? 206.732 70.592 -1.617 1.00 35.06 ? 248 ALA B CA 1 ATOM 4947 C C . ALA B 1 250 ? 207.036 71.245 -0.280 1.00 38.91 ? 248 ALA B C 1 ATOM 4948 O O . ALA B 1 250 ? 208.197 71.561 -0.019 1.00 38.56 ? 248 ALA B O 1 ATOM 4949 C CB . ALA B 1 250 ? 206.285 71.615 -2.644 1.00 34.99 ? 248 ALA B CB 1 ATOM 4950 N N . ALA B 1 251 ? 206.007 71.377 0.599 1.00 35.39 ? 249 ALA B N 1 ATOM 4951 C CA . ALA B 1 251 ? 206.158 71.921 1.957 1.00 34.49 ? 249 ALA B CA 1 ATOM 4952 C C . ALA B 1 251 ? 207.048 71.021 2.819 1.00 40.29 ? 249 ALA B C 1 ATOM 4953 O O . ALA B 1 251 ? 207.853 71.548 3.584 1.00 41.58 ? 249 ALA B O 1 ATOM 4954 C CB . ALA B 1 251 ? 204.801 72.120 2.605 1.00 34.75 ? 249 ALA B CB 1 ATOM 4955 N N . PHE B 1 252 ? 206.942 69.676 2.666 1.00 37.82 ? 250 PHE B N 1 ATOM 4956 C CA . PHE B 1 252 ? 207.776 68.693 3.370 1.00 38.80 ? 250 PHE B CA 1 ATOM 4957 C C . PHE B 1 252 ? 209.213 68.815 2.970 1.00 44.60 ? 250 PHE B C 1 ATOM 4958 O O . PHE B 1 252 ? 210.090 68.646 3.814 1.00 44.36 ? 250 PHE B O 1 ATOM 4959 C CB . PHE B 1 252 ? 207.287 67.239 3.163 1.00 40.79 ? 250 PHE B CB 1 ATOM 4960 C CG . PHE B 1 252 ? 206.306 66.792 4.223 1.00 41.49 ? 250 PHE B CG 1 ATOM 4961 C CD1 . PHE B 1 252 ? 206.735 66.520 5.523 1.00 43.62 ? 250 PHE B CD1 1 ATOM 4962 C CD2 . PHE B 1 252 ? 204.943 66.700 3.940 1.00 41.59 ? 250 PHE B CD2 1 ATOM 4963 C CE1 . PHE B 1 252 ? 205.823 66.127 6.506 1.00 43.89 ? 250 PHE B CE1 1 ATOM 4964 C CE2 . PHE B 1 252 ? 204.028 66.355 4.936 1.00 43.38 ? 250 PHE B CE2 1 ATOM 4965 C CZ . PHE B 1 252 ? 204.475 66.040 6.201 1.00 41.79 ? 250 PHE B CZ 1 ATOM 4966 N N . GLU B 1 253 ? 209.454 69.105 1.678 1.00 43.60 ? 251 GLU B N 1 ATOM 4967 C CA . GLU B 1 253 ? 210.783 69.340 1.104 1.00 44.73 ? 251 GLU B CA 1 ATOM 4968 C C . GLU B 1 253 ? 211.443 70.564 1.768 1.00 49.33 ? 251 GLU B C 1 ATOM 4969 O O . GLU B 1 253 ? 212.629 70.509 2.084 1.00 50.22 ? 251 GLU B O 1 ATOM 4970 C CB . GLU B 1 253 ? 210.692 69.535 -0.417 1.00 46.54 ? 251 GLU B CB 1 ATOM 4971 C CG . GLU B 1 253 ? 210.528 68.241 -1.199 1.00 57.98 ? 251 GLU B CG 1 ATOM 4972 C CD . GLU B 1 253 ? 210.366 68.403 -2.701 1.00 81.38 ? 251 GLU B CD 1 ATOM 4973 O OE1 . GLU B 1 253 ? 209.900 67.434 -3.343 1.00 70.38 ? 251 GLU B OE1 1 ATOM 4974 O OE2 . GLU B 1 253 ? 210.702 69.486 -3.240 1.00 75.19 ? 251 GLU B OE2 1 ATOM 4975 N N . GLY B 1 254 ? 210.660 71.621 2.016 1.00 44.99 ? 252 GLY B N 1 ATOM 4976 C CA . GLY B 1 254 ? 211.107 72.834 2.695 1.00 44.59 ? 252 GLY B CA 1 ATOM 4977 C C . GLY B 1 254 ? 211.570 72.624 4.130 1.00 49.01 ? 252 GLY B C 1 ATOM 4978 O O . GLY B 1 254 ? 212.408 73.385 4.628 1.00 49.55 ? 252 GLY B O 1 ATOM 4979 N N . VAL B 1 255 ? 211.017 71.606 4.816 1.00 44.71 ? 253 VAL B N 1 ATOM 4980 C CA . VAL B 1 255 ? 211.398 71.269 6.195 1.00 44.65 ? 253 VAL B CA 1 ATOM 4981 C C . VAL B 1 255 ? 212.791 70.632 6.123 1.00 51.62 ? 253 VAL B C 1 ATOM 4982 O O . VAL B 1 255 ? 213.693 71.004 6.885 1.00 51.27 ? 253 VAL B O 1 ATOM 4983 C CB . VAL B 1 255 ? 210.342 70.354 6.895 1.00 47.56 ? 253 VAL B CB 1 ATOM 4984 C CG1 . VAL B 1 255 ? 210.809 69.906 8.274 1.00 47.44 ? 253 VAL B CG1 1 ATOM 4985 C CG2 . VAL B 1 255 ? 208.984 71.047 6.994 1.00 46.87 ? 253 VAL B CG2 1 ATOM 4986 N N . VAL B 1 256 ? 212.966 69.711 5.156 1.00 50.05 ? 254 VAL B N 1 ATOM 4987 C CA . VAL B 1 256 ? 214.229 69.043 4.864 1.00 51.20 ? 254 VAL B CA 1 ATOM 4988 C C . VAL B 1 256 ? 215.297 70.136 4.599 1.00 56.72 ? 254 VAL B C 1 ATOM 4989 O O . VAL B 1 256 ? 216.368 70.105 5.220 1.00 56.70 ? 254 VAL B O 1 ATOM 4990 C CB . VAL B 1 256 ? 214.068 68.064 3.666 1.00 55.69 ? 254 VAL B CB 1 ATOM 4991 C CG1 . VAL B 1 256 ? 215.408 67.487 3.217 1.00 55.63 ? 254 VAL B CG1 1 ATOM 4992 C CG2 . VAL B 1 256 ? 213.086 66.949 3.995 1.00 55.48 ? 254 VAL B CG2 1 ATOM 4993 N N . ARG B 1 257 ? 214.958 71.132 3.734 1.00 52.89 ? 255 ARG B N 1 ATOM 4994 C CA . ARG B 1 257 ? 215.830 72.259 3.393 1.00 52.31 ? 255 ARG B CA 1 ATOM 4995 C C . ARG B 1 257 ? 216.218 73.061 4.647 1.00 55.86 ? 255 ARG B C 1 ATOM 4996 O O . ARG B 1 257 ? 217.409 73.312 4.856 1.00 54.77 ? 255 ARG B O 1 ATOM 4997 C CB . ARG B 1 257 ? 215.193 73.154 2.318 1.00 51.38 ? 255 ARG B CB 1 ATOM 4998 C CG . ARG B 1 257 ? 215.163 72.516 0.929 1.00 62.85 ? 255 ARG B CG 1 ATOM 4999 C CD . ARG B 1 257 ? 214.641 73.460 -0.147 1.00 69.20 ? 255 ARG B CD 1 ATOM 5000 N NE . ARG B 1 257 ? 214.135 72.734 -1.315 1.00 72.10 ? 255 ARG B NE 1 ATOM 5001 C CZ . ARG B 1 257 ? 212.846 72.611 -1.627 1.00 85.65 ? 255 ARG B CZ 1 ATOM 5002 N NH1 . ARG B 1 257 ? 211.912 73.186 -0.873 1.00 70.29 ? 255 ARG B NH1 1 ATOM 5003 N NH2 . ARG B 1 257 ? 212.480 71.922 -2.703 1.00 70.25 ? 255 ARG B NH2 1 ATOM 5004 N N . ALA B 1 258 ? 215.226 73.395 5.509 1.00 53.30 ? 256 ALA B N 1 ATOM 5005 C CA . ALA B 1 258 ? 215.432 74.136 6.767 1.00 53.98 ? 256 ALA B CA 1 ATOM 5006 C C . ALA B 1 258 ? 216.396 73.400 7.703 1.00 60.93 ? 256 ALA B C 1 ATOM 5007 O O . ALA B 1 258 ? 217.172 74.040 8.422 1.00 59.89 ? 256 ALA B O 1 ATOM 5008 C CB . ALA B 1 258 ? 214.106 74.368 7.466 1.00 54.49 ? 256 ALA B CB 1 ATOM 5009 N N . LEU B 1 259 ? 216.351 72.046 7.672 1.00 60.21 ? 257 LEU B N 1 ATOM 5010 C CA . LEU B 1 259 ? 217.226 71.178 8.459 1.00 60.61 ? 257 LEU B CA 1 ATOM 5011 C C . LEU B 1 259 ? 218.654 71.230 7.905 1.00 65.87 ? 257 LEU B C 1 ATOM 5012 O O . LEU B 1 259 ? 219.599 71.314 8.683 1.00 65.31 ? 257 LEU B O 1 ATOM 5013 C CB . LEU B 1 259 ? 216.712 69.724 8.451 1.00 60.41 ? 257 LEU B CB 1 ATOM 5014 C CG . LEU B 1 259 ? 215.365 69.429 9.103 1.00 63.92 ? 257 LEU B CG 1 ATOM 5015 C CD1 . LEU B 1 259 ? 214.954 68.000 8.840 1.00 63.08 ? 257 LEU B CD1 1 ATOM 5016 C CD2 . LEU B 1 259 ? 215.400 69.711 10.598 1.00 66.04 ? 257 LEU B CD2 1 ATOM 5017 N N . LEU B 1 260 ? 218.798 71.208 6.560 1.00 63.33 ? 258 LEU B N 1 ATOM 5018 C CA . LEU B 1 260 ? 220.077 71.249 5.838 1.00 63.13 ? 258 LEU B CA 1 ATOM 5019 C C . LEU B 1 260 ? 220.878 72.548 6.017 1.00 70.41 ? 258 LEU B C 1 ATOM 5020 O O . LEU B 1 260 ? 222.103 72.518 5.866 1.00 70.23 ? 258 LEU B O 1 ATOM 5021 C CB . LEU B 1 260 ? 219.862 70.957 4.352 1.00 62.31 ? 258 LEU B CB 1 ATOM 5022 C CG . LEU B 1 260 ? 219.447 69.546 4.009 1.00 65.93 ? 258 LEU B CG 1 ATOM 5023 C CD1 . LEU B 1 260 ? 218.807 69.491 2.641 1.00 66.05 ? 258 LEU B CD1 1 ATOM 5024 C CD2 . LEU B 1 260 ? 220.611 68.582 4.113 1.00 67.00 ? 258 LEU B CD2 1 ATOM 5025 N N . GLN B 1 261 ? 220.198 73.672 6.352 1.00 69.43 ? 259 GLN B N 1 ATOM 5026 C CA . GLN B 1 261 ? 220.796 74.993 6.613 1.00 70.89 ? 259 GLN B CA 1 ATOM 5027 C C . GLN B 1 261 ? 221.797 74.963 7.780 1.00 79.49 ? 259 GLN B C 1 ATOM 5028 O O . GLN B 1 261 ? 222.683 75.822 7.854 1.00 79.68 ? 259 GLN B O 1 ATOM 5029 C CB . GLN B 1 261 ? 219.709 76.030 6.906 1.00 72.19 ? 259 GLN B CB 1 ATOM 5030 C CG . GLN B 1 261 ? 219.133 76.681 5.667 1.00 90.90 ? 259 GLN B CG 1 ATOM 5031 C CD . GLN B 1 261 ? 217.937 77.529 6.013 1.00 117.64 ? 259 GLN B CD 1 ATOM 5032 O OE1 . GLN B 1 261 ? 217.954 78.335 6.956 1.00 112.93 ? 259 GLN B OE1 1 ATOM 5033 N NE2 . GLN B 1 261 ? 216.865 77.360 5.253 1.00 114.47 ? 259 GLN B NE2 1 ATOM 5034 N N . LYS B 1 262 ? 221.621 73.992 8.701 1.00 78.92 ? 260 LYS B N 1 ATOM 5035 C CA . LYS B 1 262 ? 222.484 73.709 9.847 1.00 79.94 ? 260 LYS B CA 1 ATOM 5036 C C . LYS B 1 262 ? 223.162 72.344 9.528 1.00 87.50 ? 260 LYS B C 1 ATOM 5037 O O . LYS B 1 262 ? 222.616 71.286 9.864 1.00 87.05 ? 260 LYS B O 1 ATOM 5038 C CB . LYS B 1 262 ? 221.658 73.680 11.144 1.00 81.87 ? 260 LYS B CB 1 ATOM 5039 C CG . LYS B 1 262 ? 220.999 75.015 11.438 1.00 98.68 ? 260 LYS B CG 1 ATOM 5040 C CD . LYS B 1 262 ? 222.008 76.107 11.792 1.00 109.40 ? 260 LYS B CD 1 ATOM 5041 C CE . LYS B 1 262 ? 221.321 77.427 12.080 1.00 117.03 ? 260 LYS B CE 1 ATOM 5042 N NZ . LYS B 1 262 ? 220.458 77.369 13.290 1.00 121.12 ? 260 LYS B NZ 1 ATOM 5043 N N . PRO B 1 263 ? 224.291 72.341 8.767 1.00 86.87 ? 261 PRO B N 1 ATOM 5044 C CA . PRO B 1 263 ? 224.892 71.051 8.355 1.00 87.48 ? 261 PRO B CA 1 ATOM 5045 C C . PRO B 1 263 ? 225.710 70.319 9.428 1.00 92.22 ? 261 PRO B C 1 ATOM 5046 O O . PRO B 1 263 ? 226.052 69.144 9.233 1.00 91.77 ? 261 PRO B O 1 ATOM 5047 C CB . PRO B 1 263 ? 225.735 71.419 7.128 1.00 89.18 ? 261 PRO B CB 1 ATOM 5048 C CG . PRO B 1 263 ? 226.054 72.871 7.294 1.00 93.29 ? 261 PRO B CG 1 ATOM 5049 C CD . PRO B 1 263 ? 225.060 73.492 8.242 1.00 88.61 ? 261 PRO B CD 1 ATOM 5050 N N . SER B 1 264 ? 226.011 71.004 10.557 1.00 88.90 ? 262 SER B N 1 ATOM 5051 C CA . SER B 1 264 ? 226.752 70.450 11.696 1.00 88.71 ? 262 SER B CA 1 ATOM 5052 C C . SER B 1 264 ? 225.893 69.385 12.405 1.00 92.68 ? 262 SER B C 1 ATOM 5053 O O . SER B 1 264 ? 226.431 68.382 12.889 1.00 93.13 ? 262 SER B O 1 ATOM 5054 C CB . SER B 1 264 ? 227.136 71.562 12.671 1.00 92.05 ? 262 SER B CB 1 ATOM 5055 O OG . SER B 1 264 ? 227.966 71.091 13.720 1.00 100.12 ? 262 SER B OG 1 ATOM 5056 N N . ALA B 1 265 ? 224.552 69.610 12.444 1.00 87.51 ? 263 ALA B N 1 ATOM 5057 C CA . ALA B 1 265 ? 223.561 68.713 13.045 1.00 85.49 ? 263 ALA B CA 1 ATOM 5058 C C . ALA B 1 265 ? 222.995 67.766 11.991 1.00 84.46 ? 263 ALA B C 1 ATOM 5059 O O . ALA B 1 265 ? 222.041 68.108 11.284 1.00 83.00 ? 263 ALA B O 1 ATOM 5060 C CB . ALA B 1 265 ? 222.446 69.517 13.689 1.00 86.07 ? 263 ALA B CB 1 ATOM 5061 N N . ARG B 1 266 ? 223.615 66.585 11.870 1.00 78.87 ? 264 ARG B N 1 ATOM 5062 C CA . ARG B 1 266 ? 223.212 65.536 10.922 1.00 77.63 ? 264 ARG B CA 1 ATOM 5063 C C . ARG B 1 266 ? 222.168 64.602 11.557 1.00 75.79 ? 264 ARG B C 1 ATOM 5064 O O . ARG B 1 266 ? 221.555 63.812 10.847 1.00 74.60 ? 264 ARG B O 1 ATOM 5065 C CB . ARG B 1 266 ? 224.437 64.721 10.446 1.00 80.43 ? 264 ARG B CB 1 ATOM 5066 C CG . ARG B 1 266 ? 225.513 65.534 9.722 1.00 96.90 ? 264 ARG B CG 1 ATOM 5067 C CD . ARG B 1 266 ? 226.883 64.900 9.880 1.00 113.72 ? 264 ARG B CD 1 ATOM 5068 N NE . ARG B 1 266 ? 227.918 65.625 9.139 1.00 126.50 ? 264 ARG B NE 1 ATOM 5069 C CZ . ARG B 1 266 ? 229.204 65.278 9.104 1.00 138.71 ? 264 ARG B CZ 1 ATOM 5070 N NH1 . ARG B 1 266 ? 229.632 64.214 9.775 1.00 125.17 ? 264 ARG B NH1 1 ATOM 5071 N NH2 . ARG B 1 266 ? 230.070 65.993 8.398 1.00 121.33 ? 264 ARG B NH2 1 ATOM 5072 N N . VAL B 1 267 ? 221.975 64.698 12.893 1.00 68.76 ? 265 VAL B N 1 ATOM 5073 C CA . VAL B 1 267 ? 221.031 63.879 13.660 1.00 66.34 ? 265 VAL B CA 1 ATOM 5074 C C . VAL B 1 267 ? 219.707 64.614 13.842 1.00 65.60 ? 265 VAL B C 1 ATOM 5075 O O . VAL B 1 267 ? 219.683 65.701 14.434 1.00 64.62 ? 265 VAL B O 1 ATOM 5076 C CB . VAL B 1 267 ? 221.607 63.381 15.016 1.00 69.56 ? 265 VAL B CB 1 ATOM 5077 C CG1 . VAL B 1 267 ? 220.638 62.430 15.716 1.00 69.05 ? 265 VAL B CG1 1 ATOM 5078 C CG2 . VAL B 1 267 ? 222.961 62.715 14.831 1.00 69.37 ? 265 VAL B CG2 1 ATOM 5079 N N . ALA B 1 268 ? 218.606 64.000 13.347 1.00 58.90 ? 266 ALA B N 1 ATOM 5080 C CA . ALA B 1 268 ? 217.256 64.558 13.457 1.00 57.13 ? 266 ALA B CA 1 ATOM 5081 C C . ALA B 1 268 ? 216.353 63.680 14.335 1.00 56.84 ? 266 ALA B C 1 ATOM 5082 O O . ALA B 1 268 ? 216.122 62.503 14.030 1.00 55.64 ? 266 ALA B O 1 ATOM 5083 C CB . ALA B 1 268 ? 216.650 64.777 12.081 1.00 57.72 ? 266 ALA B CB 1 ATOM 5084 N N . VAL B 1 269 ? 215.889 64.265 15.457 1.00 49.95 ? 267 VAL B N 1 ATOM 5085 C CA . VAL B 1 269 ? 215.048 63.625 16.470 1.00 47.75 ? 267 VAL B CA 1 ATOM 5086 C C . VAL B 1 269 ? 213.584 63.872 16.124 1.00 50.13 ? 267 VAL B C 1 ATOM 5087 O O . VAL B 1 269 ? 213.147 65.029 16.103 1.00 51.27 ? 267 VAL B O 1 ATOM 5088 C CB . VAL B 1 269 ? 215.419 64.124 17.893 1.00 50.18 ? 267 VAL B CB 1 ATOM 5089 C CG1 . VAL B 1 269 ? 214.500 63.537 18.947 1.00 49.65 ? 267 VAL B CG1 1 ATOM 5090 C CG2 . VAL B 1 269 ? 216.870 63.812 18.221 1.00 49.58 ? 267 VAL B CG2 1 ATOM 5091 N N . LEU B 1 270 ? 212.830 62.794 15.837 1.00 43.28 ? 268 LEU B N 1 ATOM 5092 C CA . LEU B 1 270 ? 211.422 62.912 15.472 1.00 41.20 ? 268 LEU B CA 1 ATOM 5093 C C . LEU B 1 270 ? 210.433 62.455 16.529 1.00 43.32 ? 268 LEU B C 1 ATOM 5094 O O . LEU B 1 270 ? 210.553 61.354 17.075 1.00 42.77 ? 268 LEU B O 1 ATOM 5095 C CB . LEU B 1 270 ? 211.069 62.197 14.153 1.00 41.00 ? 268 LEU B CB 1 ATOM 5096 C CG . LEU B 1 270 ? 212.006 62.211 12.948 1.00 45.08 ? 268 LEU B CG 1 ATOM 5097 C CD1 . LEU B 1 270 ? 211.337 61.524 11.772 1.00 44.92 ? 268 LEU B CD1 1 ATOM 5098 C CD2 . LEU B 1 270 ? 212.426 63.609 12.558 1.00 46.71 ? 268 LEU B CD2 1 ATOM 5099 N N . PHE B 1 271 ? 209.415 63.301 16.773 1.00 38.24 ? 269 PHE B N 1 ATOM 5100 C CA . PHE B 1 271 ? 208.262 62.988 17.607 1.00 37.17 ? 269 PHE B CA 1 ATOM 5101 C C . PHE B 1 271 ? 207.062 63.228 16.700 1.00 41.79 ? 269 PHE B C 1 ATOM 5102 O O . PHE B 1 271 ? 206.268 64.153 16.870 1.00 41.59 ? 269 PHE B O 1 ATOM 5103 C CB . PHE B 1 271 ? 208.215 63.774 18.924 1.00 38.13 ? 269 PHE B CB 1 ATOM 5104 C CG . PHE B 1 271 ? 208.058 62.854 20.110 1.00 38.38 ? 269 PHE B CG 1 ATOM 5105 C CD1 . PHE B 1 271 ? 206.832 62.258 20.395 1.00 40.28 ? 269 PHE B CD1 1 ATOM 5106 C CD2 . PHE B 1 271 ? 209.145 62.551 20.924 1.00 39.67 ? 269 PHE B CD2 1 ATOM 5107 C CE1 . PHE B 1 271 ? 206.696 61.375 21.472 1.00 40.42 ? 269 PHE B CE1 1 ATOM 5108 C CE2 . PHE B 1 271 ? 209.001 61.690 22.021 1.00 41.85 ? 269 PHE B CE2 1 ATOM 5109 C CZ . PHE B 1 271 ? 207.781 61.096 22.276 1.00 39.48 ? 269 PHE B CZ 1 ATOM 5110 N N . THR B 1 272 ? 206.989 62.399 15.671 1.00 38.68 ? 270 THR B N 1 ATOM 5111 C CA . THR B 1 272 ? 205.998 62.525 14.617 1.00 37.79 ? 270 THR B CA 1 ATOM 5112 C C . THR B 1 272 ? 205.010 61.376 14.463 1.00 38.19 ? 270 THR B C 1 ATOM 5113 O O . THR B 1 272 ? 205.303 60.207 14.758 1.00 36.35 ? 270 THR B O 1 ATOM 5114 C CB . THR B 1 272 ? 206.720 62.741 13.279 1.00 42.46 ? 270 THR B CB 1 ATOM 5115 O OG1 . THR B 1 272 ? 207.668 61.689 13.126 1.00 40.87 ? 270 THR B OG1 1 ATOM 5116 C CG2 . THR B 1 272 ? 207.415 64.102 13.194 1.00 39.82 ? 270 THR B CG2 1 ATOM 5117 N N . ARG B 1 273 ? 203.846 61.741 13.912 1.00 33.48 ? 271 ARG B N 1 ATOM 5118 C CA . ARG B 1 273 ? 202.791 60.844 13.477 1.00 33.40 ? 271 ARG B CA 1 ATOM 5119 C C . ARG B 1 273 ? 203.394 60.075 12.281 1.00 40.66 ? 271 ARG B C 1 ATOM 5120 O O . ARG B 1 273 ? 204.232 60.626 11.550 1.00 42.51 ? 271 ARG B O 1 ATOM 5121 C CB . ARG B 1 273 ? 201.540 61.657 13.076 1.00 30.01 ? 271 ARG B CB 1 ATOM 5122 C CG . ARG B 1 273 ? 200.927 62.414 14.277 1.00 37.11 ? 271 ARG B CG 1 ATOM 5123 C CD . ARG B 1 273 ? 199.785 63.365 13.962 1.00 35.95 ? 271 ARG B CD 1 ATOM 5124 N NE . ARG B 1 273 ? 198.744 62.743 13.135 1.00 44.75 ? 271 ARG B NE 1 ATOM 5125 C CZ . ARG B 1 273 ? 197.476 62.575 13.504 1.00 53.21 ? 271 ARG B CZ 1 ATOM 5126 N NH1 . ARG B 1 273 ? 196.603 62.018 12.668 1.00 29.46 ? 271 ARG B NH1 1 ATOM 5127 N NH2 . ARG B 1 273 ? 197.072 62.950 14.710 1.00 44.89 ? 271 ARG B NH2 1 ATOM 5128 N N . SER B 1 274 ? 203.043 58.797 12.130 1.00 37.02 ? 272 SER B N 1 ATOM 5129 C CA . SER B 1 274 ? 203.571 57.925 11.060 1.00 36.13 ? 272 SER B CA 1 ATOM 5130 C C . SER B 1 274 ? 203.539 58.550 9.656 1.00 39.61 ? 272 SER B C 1 ATOM 5131 O O . SER B 1 274 ? 204.529 58.460 8.930 1.00 39.52 ? 272 SER B O 1 ATOM 5132 C CB . SER B 1 274 ? 202.831 56.590 11.048 1.00 37.12 ? 272 SER B CB 1 ATOM 5133 O OG . SER B 1 274 ? 201.442 56.792 10.847 1.00 42.87 ? 272 SER B OG 1 ATOM 5134 N N . GLU B 1 275 ? 202.400 59.167 9.287 1.00 35.46 ? 273 GLU B N 1 ATOM 5135 C CA . GLU B 1 275 ? 202.176 59.809 7.994 1.00 35.96 ? 273 GLU B CA 1 ATOM 5136 C C . GLU B 1 275 ? 203.180 60.957 7.713 1.00 41.31 ? 273 GLU B C 1 ATOM 5137 O O . GLU B 1 275 ? 203.557 61.177 6.564 1.00 39.89 ? 273 GLU B O 1 ATOM 5138 C CB . GLU B 1 275 ? 200.700 60.266 7.854 1.00 37.57 ? 273 GLU B CB 1 ATOM 5139 C CG . GLU B 1 275 ? 200.178 61.265 8.894 1.00 49.64 ? 273 GLU B CG 1 ATOM 5140 C CD . GLU B 1 275 ? 199.315 60.696 10.016 1.00 69.73 ? 273 GLU B CD 1 ATOM 5141 O OE1 . GLU B 1 275 ? 198.248 61.297 10.303 1.00 44.74 ? 273 GLU B OE1 1 ATOM 5142 O OE2 . GLU B 1 275 ? 199.705 59.655 10.605 1.00 52.86 ? 273 GLU B OE2 1 ATOM 5143 N N . ASP B 1 276 ? 203.613 61.656 8.774 1.00 40.95 ? 274 ASP B N 1 ATOM 5144 C CA . ASP B 1 276 ? 204.583 62.756 8.744 1.00 42.06 ? 274 ASP B CA 1 ATOM 5145 C C . ASP B 1 276 ? 205.982 62.199 8.612 1.00 47.10 ? 274 ASP B C 1 ATOM 5146 O O . ASP B 1 276 ? 206.733 62.664 7.763 1.00 48.28 ? 274 ASP B O 1 ATOM 5147 C CB . ASP B 1 276 ? 204.436 63.655 9.988 1.00 44.04 ? 274 ASP B CB 1 ATOM 5148 C CG . ASP B 1 276 ? 203.080 64.339 10.057 1.00 61.00 ? 274 ASP B CG 1 ATOM 5149 O OD1 . ASP B 1 276 ? 202.350 64.335 9.031 1.00 61.25 ? 274 ASP B OD1 1 ATOM 5150 O OD2 . ASP B 1 276 ? 202.777 64.944 11.100 1.00 72.50 ? 274 ASP B OD2 1 ATOM 5151 N N . ALA B 1 277 ? 206.316 61.168 9.408 1.00 42.50 ? 275 ALA B N 1 ATOM 5152 C CA . ALA B 1 277 ? 207.587 60.466 9.321 1.00 41.10 ? 275 ALA B CA 1 ATOM 5153 C C . ALA B 1 277 ? 207.747 59.923 7.871 1.00 43.33 ? 275 ALA B C 1 ATOM 5154 O O . ALA B 1 277 ? 208.779 60.165 7.251 1.00 41.35 ? 275 ALA B O 1 ATOM 5155 C CB . ALA B 1 277 ? 207.602 59.333 10.328 1.00 41.45 ? 275 ALA B CB 1 ATOM 5156 N N . ARG B 1 278 ? 206.681 59.299 7.304 1.00 40.23 ? 276 ARG B N 1 ATOM 5157 C CA . ARG B 1 278 ? 206.666 58.764 5.931 1.00 40.21 ? 276 ARG B CA 1 ATOM 5158 C C . ARG B 1 278 ? 206.956 59.878 4.907 1.00 47.05 ? 276 ARG B C 1 ATOM 5159 O O . ARG B 1 278 ? 207.881 59.746 4.093 1.00 48.83 ? 276 ARG B O 1 ATOM 5160 C CB . ARG B 1 278 ? 205.331 58.035 5.607 1.00 35.51 ? 276 ARG B CB 1 ATOM 5161 C CG . ARG B 1 278 ? 205.131 57.765 4.116 1.00 40.09 ? 276 ARG B CG 1 ATOM 5162 C CD . ARG B 1 278 ? 203.874 57.034 3.659 1.00 48.94 ? 276 ARG B CD 1 ATOM 5163 N NE . ARG B 1 278 ? 202.670 57.297 4.453 1.00 70.14 ? 276 ARG B NE 1 ATOM 5164 C CZ . ARG B 1 278 ? 201.812 58.292 4.244 1.00 79.32 ? 276 ARG B CZ 1 ATOM 5165 N NH1 . ARG B 1 278 ? 202.032 59.177 3.276 1.00 59.96 ? 276 ARG B NH1 1 ATOM 5166 N NH2 . ARG B 1 278 ? 200.737 58.422 5.016 1.00 58.97 ? 276 ARG B NH2 1 ATOM 5167 N N . GLU B 1 279 ? 206.166 60.960 4.957 1.00 42.13 ? 277 GLU B N 1 ATOM 5168 C CA . GLU B 1 279 ? 206.270 62.101 4.050 1.00 41.03 ? 277 GLU B CA 1 ATOM 5169 C C . GLU B 1 279 ? 207.606 62.836 4.130 1.00 42.01 ? 277 GLU B C 1 ATOM 5170 O O . GLU B 1 279 ? 208.126 63.242 3.092 1.00 41.54 ? 277 GLU B O 1 ATOM 5171 C CB . GLU B 1 279 ? 205.091 63.067 4.252 1.00 42.32 ? 277 GLU B CB 1 ATOM 5172 C CG . GLU B 1 279 ? 203.789 62.626 3.600 1.00 52.03 ? 277 GLU B CG 1 ATOM 5173 C CD . GLU B 1 279 ? 203.865 62.277 2.124 1.00 89.04 ? 277 GLU B CD 1 ATOM 5174 O OE1 . GLU B 1 279 ? 203.379 61.184 1.749 1.00 80.42 ? 277 GLU B OE1 1 ATOM 5175 O OE2 . GLU B 1 279 ? 204.442 63.075 1.348 1.00 96.84 ? 277 GLU B OE2 1 ATOM 5176 N N . LEU B 1 280 ? 208.156 62.987 5.341 1.00 36.87 ? 278 LEU B N 1 ATOM 5177 C CA . LEU B 1 280 ? 209.430 63.645 5.594 1.00 37.32 ? 278 LEU B CA 1 ATOM 5178 C C . LEU B 1 280 ? 210.592 62.832 5.033 1.00 45.80 ? 278 LEU B C 1 ATOM 5179 O O . LEU B 1 280 ? 211.536 63.409 4.501 1.00 45.46 ? 278 LEU B O 1 ATOM 5180 C CB . LEU B 1 280 ? 209.601 63.872 7.103 1.00 37.69 ? 278 LEU B CB 1 ATOM 5181 C CG . LEU B 1 280 ? 210.782 64.735 7.576 1.00 43.16 ? 278 LEU B CG 1 ATOM 5182 C CD1 . LEU B 1 280 ? 210.682 66.188 7.067 1.00 43.24 ? 278 LEU B CD1 1 ATOM 5183 C CD2 . LEU B 1 280 ? 210.909 64.695 9.092 1.00 43.93 ? 278 LEU B CD2 1 ATOM 5184 N N . LEU B 1 281 ? 210.519 61.501 5.140 1.00 46.80 ? 279 LEU B N 1 ATOM 5185 C CA . LEU B 1 281 ? 211.537 60.577 4.643 1.00 48.87 ? 279 LEU B CA 1 ATOM 5186 C C . LEU B 1 281 ? 211.588 60.584 3.107 1.00 54.42 ? 279 LEU B C 1 ATOM 5187 O O . LEU B 1 281 ? 212.675 60.531 2.517 1.00 54.84 ? 279 LEU B O 1 ATOM 5188 C CB . LEU B 1 281 ? 211.237 59.156 5.179 1.00 49.98 ? 279 LEU B CB 1 ATOM 5189 C CG . LEU B 1 281 ? 211.923 58.712 6.492 1.00 56.27 ? 279 LEU B CG 1 ATOM 5190 C CD1 . LEU B 1 281 ? 213.306 58.243 6.235 1.00 56.78 ? 279 LEU B CD1 1 ATOM 5191 C CD2 . LEU B 1 281 ? 211.978 59.837 7.535 1.00 61.12 ? 279 LEU B CD2 1 ATOM 5192 N N . ALA B 1 282 ? 210.395 60.676 2.477 1.00 50.47 ? 280 ALA B N 1 ATOM 5193 C CA . ALA B 1 282 ? 210.171 60.726 1.032 1.00 49.71 ? 280 ALA B CA 1 ATOM 5194 C C . ALA B 1 282 ? 210.803 61.967 0.430 1.00 55.57 ? 280 ALA B C 1 ATOM 5195 O O . ALA B 1 282 ? 211.311 61.913 -0.694 1.00 55.85 ? 280 ALA B O 1 ATOM 5196 C CB . ALA B 1 282 ? 208.676 60.724 0.743 1.00 49.95 ? 280 ALA B CB 1 ATOM 5197 N N . ALA B 1 283 ? 210.731 63.098 1.167 1.00 52.25 ? 281 ALA B N 1 ATOM 5198 C CA . ALA B 1 283 ? 211.285 64.374 0.745 1.00 51.89 ? 281 ALA B CA 1 ATOM 5199 C C . ALA B 1 283 ? 212.821 64.347 0.871 1.00 55.50 ? 281 ALA B C 1 ATOM 5200 O O . ALA B 1 283 ? 213.508 64.824 -0.030 1.00 53.78 ? 281 ALA B O 1 ATOM 5201 C CB . ALA B 1 283 ? 210.676 65.496 1.560 1.00 52.73 ? 281 ALA B CB 1 ATOM 5202 N N . SER B 1 284 ? 213.354 63.699 1.935 1.00 53.67 ? 282 SER B N 1 ATOM 5203 C CA . SER B 1 284 ? 214.793 63.499 2.142 1.00 54.06 ? 282 SER B CA 1 ATOM 5204 C C . SER B 1 284 ? 215.333 62.640 1.002 1.00 60.60 ? 282 SER B C 1 ATOM 5205 O O . SER B 1 284 ? 216.464 62.854 0.550 1.00 61.74 ? 282 SER B O 1 ATOM 5206 C CB . SER B 1 284 ? 215.053 62.769 3.451 1.00 57.06 ? 282 SER B CB 1 ATOM 5207 O OG . SER B 1 284 ? 214.490 63.471 4.542 1.00 69.56 ? 282 SER B OG 1 ATOM 5208 N N . GLN B 1 285 ? 214.521 61.652 0.550 1.00 56.54 ? 283 GLN B N 1 ATOM 5209 C CA . GLN B 1 285 ? 214.877 60.773 -0.557 1.00 56.10 ? 283 GLN B CA 1 ATOM 5210 C C . GLN B 1 285 ? 214.974 61.639 -1.826 1.00 60.81 ? 283 GLN B C 1 ATOM 5211 O O . GLN B 1 285 ? 216.079 61.837 -2.332 1.00 60.95 ? 283 GLN B O 1 ATOM 5212 C CB . GLN B 1 285 ? 213.865 59.614 -0.691 1.00 56.87 ? 283 GLN B CB 1 ATOM 5213 C CG . GLN B 1 285 ? 214.225 58.569 -1.736 1.00 61.05 ? 283 GLN B CG 1 ATOM 5214 C CD . GLN B 1 285 ? 215.301 57.615 -1.278 1.00 89.44 ? 283 GLN B CD 1 ATOM 5215 O OE1 . GLN B 1 285 ? 215.033 56.448 -0.973 1.00 92.61 ? 283 GLN B OE1 1 ATOM 5216 N NE2 . GLN B 1 285 ? 216.552 58.064 -1.274 1.00 77.14 ? 283 GLN B NE2 1 ATOM 5217 N N . ARG B 1 286 ? 213.843 62.240 -2.251 1.00 57.24 ? 284 ARG B N 1 ATOM 5218 C CA . ARG B 1 286 ? 213.719 63.150 -3.391 1.00 57.42 ? 284 ARG B CA 1 ATOM 5219 C C . ARG B 1 286 ? 214.785 64.245 -3.448 1.00 63.16 ? 284 ARG B C 1 ATOM 5220 O O . ARG B 1 286 ? 215.164 64.639 -4.546 1.00 64.60 ? 284 ARG B O 1 ATOM 5221 C CB . ARG B 1 286 ? 212.346 63.828 -3.391 1.00 56.39 ? 284 ARG B CB 1 ATOM 5222 C CG . ARG B 1 286 ? 211.200 62.931 -3.809 1.00 59.27 ? 284 ARG B CG 1 ATOM 5223 C CD . ARG B 1 286 ? 209.990 63.754 -4.206 1.00 58.56 ? 284 ARG B CD 1 ATOM 5224 N NE . ARG B 1 286 ? 209.558 64.693 -3.167 1.00 59.08 ? 284 ARG B NE 1 ATOM 5225 C CZ . ARG B 1 286 ? 208.707 64.398 -2.189 1.00 70.27 ? 284 ARG B CZ 1 ATOM 5226 N NH1 . ARG B 1 286 ? 208.359 65.323 -1.305 1.00 61.30 ? 284 ARG B NH1 1 ATOM 5227 N NH2 . ARG B 1 286 ? 208.192 63.177 -2.091 1.00 47.98 ? 284 ARG B NH2 1 ATOM 5228 N N . LEU B 1 287 ? 215.235 64.767 -2.295 1.00 59.32 ? 285 LEU B N 1 ATOM 5229 C CA . LEU B 1 287 ? 216.239 65.831 -2.275 1.00 59.46 ? 285 LEU B CA 1 ATOM 5230 C C . LEU B 1 287 ? 217.651 65.316 -1.992 1.00 66.69 ? 285 LEU B C 1 ATOM 5231 O O . LEU B 1 287 ? 218.572 66.126 -1.802 1.00 66.30 ? 285 LEU B O 1 ATOM 5232 C CB . LEU B 1 287 ? 215.865 66.933 -1.260 1.00 59.09 ? 285 LEU B CB 1 ATOM 5233 C CG . LEU B 1 287 ? 214.560 67.716 -1.439 1.00 62.07 ? 285 LEU B CG 1 ATOM 5234 C CD1 . LEU B 1 287 ? 214.359 68.644 -0.272 1.00 61.89 ? 285 LEU B CD1 1 ATOM 5235 C CD2 . LEU B 1 287 ? 214.522 68.486 -2.750 1.00 61.97 ? 285 LEU B CD2 1 ATOM 5236 N N . ASN B 1 288 ? 217.816 63.965 -1.945 1.00 65.47 ? 286 ASN B N 1 ATOM 5237 C CA . ASN B 1 288 ? 219.069 63.236 -1.670 1.00 65.63 ? 286 ASN B CA 1 ATOM 5238 C C . ASN B 1 288 ? 219.790 63.759 -0.420 1.00 67.46 ? 286 ASN B C 1 ATOM 5239 O O . ASN B 1 288 ? 221.014 63.924 -0.414 1.00 66.60 ? 286 ASN B O 1 ATOM 5240 C CB . ASN B 1 288 ? 219.987 63.209 -2.912 1.00 71.82 ? 286 ASN B CB 1 ATOM 5241 C CG . ASN B 1 288 ? 221.079 62.166 -2.867 1.00 113.38 ? 286 ASN B CG 1 ATOM 5242 O OD1 . ASN B 1 288 ? 220.854 61.004 -2.470 1.00 107.29 ? 286 ASN B OD1 1 ATOM 5243 N ND2 . ASN B 1 288 ? 222.283 62.590 -3.284 1.00 115.34 ? 286 ASN B ND2 1 ATOM 5244 N N . ALA B 1 289 ? 219.005 64.043 0.638 1.00 63.73 ? 287 ALA B N 1 ATOM 5245 C CA . ALA B 1 289 ? 219.523 64.544 1.915 1.00 62.94 ? 287 ALA B CA 1 ATOM 5246 C C . ALA B 1 289 ? 219.861 63.366 2.781 1.00 65.43 ? 287 ALA B C 1 ATOM 5247 O O . ALA B 1 289 ? 219.261 62.298 2.610 1.00 64.77 ? 287 ALA B O 1 ATOM 5248 C CB . ALA B 1 289 ? 218.496 65.429 2.606 1.00 63.48 ? 287 ALA B CB 1 ATOM 5249 N N . SER B 1 290 ? 220.846 63.541 3.681 1.00 61.59 ? 288 SER B N 1 ATOM 5250 C CA . SER B 1 290 ? 221.290 62.485 4.582 1.00 61.25 ? 288 SER B CA 1 ATOM 5251 C C . SER B 1 290 ? 221.289 62.933 6.022 1.00 63.77 ? 288 SER B C 1 ATOM 5252 O O . SER B 1 290 ? 221.999 63.882 6.385 1.00 63.08 ? 288 SER B O 1 ATOM 5253 C CB . SER B 1 290 ? 222.645 61.922 4.162 1.00 65.76 ? 288 SER B CB 1 ATOM 5254 O OG . SER B 1 290 ? 222.495 61.037 3.060 1.00 76.74 ? 288 SER B OG 1 ATOM 5255 N N . PHE B 1 291 ? 220.436 62.247 6.834 1.00 58.57 ? 289 PHE B N 1 ATOM 5256 C CA . PHE B 1 291 ? 220.226 62.461 8.268 1.00 56.55 ? 289 PHE B CA 1 ATOM 5257 C C . PHE B 1 291 ? 220.250 61.153 9.063 1.00 59.94 ? 289 PHE B C 1 ATOM 5258 O O . PHE B 1 291 ? 219.861 60.093 8.549 1.00 60.21 ? 289 PHE B O 1 ATOM 5259 C CB . PHE B 1 291 ? 218.870 63.150 8.521 1.00 57.30 ? 289 PHE B CB 1 ATOM 5260 C CG . PHE B 1 291 ? 218.714 64.520 7.918 1.00 57.81 ? 289 PHE B CG 1 ATOM 5261 C CD1 . PHE B 1 291 ? 219.225 65.642 8.559 1.00 60.31 ? 289 PHE B CD1 1 ATOM 5262 C CD2 . PHE B 1 291 ? 218.031 64.694 6.717 1.00 59.78 ? 289 PHE B CD2 1 ATOM 5263 C CE1 . PHE B 1 291 ? 219.084 66.911 7.998 1.00 61.46 ? 289 PHE B CE1 1 ATOM 5264 C CE2 . PHE B 1 291 ? 217.876 65.967 6.159 1.00 62.63 ? 289 PHE B CE2 1 ATOM 5265 C CZ . PHE B 1 291 ? 218.412 67.066 6.797 1.00 60.81 ? 289 PHE B CZ 1 ATOM 5266 N N . THR B 1 292 ? 220.653 61.249 10.338 1.00 55.01 ? 290 THR B N 1 ATOM 5267 C CA . THR B 1 292 ? 220.629 60.142 11.292 1.00 54.58 ? 290 THR B CA 1 ATOM 5268 C C . THR B 1 292 ? 219.315 60.345 12.062 1.00 58.46 ? 290 THR B C 1 ATOM 5269 O O . THR B 1 292 ? 219.189 61.278 12.867 1.00 58.43 ? 290 THR B O 1 ATOM 5270 C CB . THR B 1 292 ? 221.876 60.173 12.188 1.00 55.95 ? 290 THR B CB 1 ATOM 5271 O OG1 . THR B 1 292 ? 223.022 60.009 11.360 1.00 59.49 ? 290 THR B OG1 1 ATOM 5272 C CG2 . THR B 1 292 ? 221.850 59.111 13.277 1.00 47.68 ? 290 THR B CG2 1 ATOM 5273 N N . TRP B 1 293 ? 218.313 59.531 11.749 1.00 53.15 ? 291 TRP B N 1 ATOM 5274 C CA . TRP B 1 293 ? 217.030 59.697 12.400 1.00 51.68 ? 291 TRP B CA 1 ATOM 5275 C C . TRP B 1 293 ? 216.979 58.983 13.737 1.00 55.63 ? 291 TRP B C 1 ATOM 5276 O O . TRP B 1 293 ? 217.476 57.869 13.855 1.00 56.80 ? 291 TRP B O 1 ATOM 5277 C CB . TRP B 1 293 ? 215.890 59.209 11.510 1.00 49.73 ? 291 TRP B CB 1 ATOM 5278 C CG . TRP B 1 293 ? 215.900 59.738 10.110 1.00 50.27 ? 291 TRP B CG 1 ATOM 5279 C CD1 . TRP B 1 293 ? 216.231 59.050 8.981 1.00 52.95 ? 291 TRP B CD1 1 ATOM 5280 C CD2 . TRP B 1 293 ? 215.486 61.040 9.681 1.00 50.11 ? 291 TRP B CD2 1 ATOM 5281 N NE1 . TRP B 1 293 ? 216.056 59.842 7.876 1.00 52.25 ? 291 TRP B NE1 1 ATOM 5282 C CE2 . TRP B 1 293 ? 215.612 61.076 8.276 1.00 54.17 ? 291 TRP B CE2 1 ATOM 5283 C CE3 . TRP B 1 293 ? 215.016 62.185 10.349 1.00 51.52 ? 291 TRP B CE3 1 ATOM 5284 C CZ2 . TRP B 1 293 ? 215.277 62.215 7.520 1.00 53.87 ? 291 TRP B CZ2 1 ATOM 5285 C CZ3 . TRP B 1 293 ? 214.679 63.309 9.607 1.00 53.08 ? 291 TRP B CZ3 1 ATOM 5286 C CH2 . TRP B 1 293 ? 214.811 63.319 8.209 1.00 53.95 ? 291 TRP B CH2 1 ATOM 5287 N N . VAL B 1 294 ? 216.368 59.635 14.742 1.00 50.07 ? 292 VAL B N 1 ATOM 5288 C CA . VAL B 1 294 ? 216.085 59.101 16.075 1.00 48.26 ? 292 VAL B CA 1 ATOM 5289 C C . VAL B 1 294 ? 214.594 59.382 16.251 1.00 48.42 ? 292 VAL B C 1 ATOM 5290 O O . VAL B 1 294 ? 214.215 60.509 16.571 1.00 47.26 ? 292 VAL B O 1 ATOM 5291 C CB . VAL B 1 294 ? 216.963 59.704 17.210 1.00 51.65 ? 292 VAL B CB 1 ATOM 5292 C CG1 . VAL B 1 294 ? 216.583 59.117 18.569 1.00 50.86 ? 292 VAL B CG1 1 ATOM 5293 C CG2 . VAL B 1 294 ? 218.450 59.488 16.930 1.00 51.49 ? 292 VAL B CG2 1 ATOM 5294 N N . ALA B 1 295 ? 213.748 58.381 15.958 1.00 43.06 ? 293 ALA B N 1 ATOM 5295 C CA . ALA B 1 295 ? 212.297 58.548 16.027 1.00 41.31 ? 293 ALA B CA 1 ATOM 5296 C C . ALA B 1 295 ? 211.600 57.855 17.169 1.00 41.85 ? 293 ALA B C 1 ATOM 5297 O O . ALA B 1 295 ? 212.046 56.813 17.652 1.00 40.55 ? 293 ALA B O 1 ATOM 5298 C CB . ALA B 1 295 ? 211.657 58.121 14.728 1.00 41.85 ? 293 ALA B CB 1 ATOM 5299 N N . SER B 1 296 ? 210.429 58.427 17.534 1.00 36.61 ? 294 SER B N 1 ATOM 5300 C CA . SER B 1 296 ? 209.478 57.942 18.529 1.00 34.53 ? 294 SER B CA 1 ATOM 5301 C C . SER B 1 296 ? 208.575 56.793 17.940 1.00 35.74 ? 294 SER B C 1 ATOM 5302 O O . SER B 1 296 ? 208.752 56.405 16.794 1.00 34.84 ? 294 SER B O 1 ATOM 5303 C CB . SER B 1 296 ? 208.658 59.107 19.079 1.00 34.39 ? 294 SER B CB 1 ATOM 5304 O OG . SER B 1 296 ? 207.906 59.728 18.050 1.00 34.50 ? 294 SER B OG 1 ATOM 5305 N N . ASP B 1 297 ? 207.633 56.264 18.734 1.00 31.97 ? 295 ASP B N 1 ATOM 5306 C CA . ASP B 1 297 ? 206.753 55.142 18.438 1.00 31.80 ? 295 ASP B CA 1 ATOM 5307 C C . ASP B 1 297 ? 205.840 55.360 17.228 1.00 37.03 ? 295 ASP B C 1 ATOM 5308 O O . ASP B 1 297 ? 205.282 54.384 16.697 1.00 36.96 ? 295 ASP B O 1 ATOM 5309 C CB . ASP B 1 297 ? 205.943 54.757 19.692 1.00 33.38 ? 295 ASP B CB 1 ATOM 5310 C CG . ASP B 1 297 ? 204.861 55.766 20.077 1.00 42.80 ? 295 ASP B CG 1 ATOM 5311 O OD1 . ASP B 1 297 ? 205.213 56.925 20.396 1.00 42.10 ? 295 ASP B OD1 1 ATOM 5312 O OD2 . ASP B 1 297 ? 203.663 55.381 20.092 1.00 46.16 ? 295 ASP B OD2 1 ATOM 5313 N N . GLY B 1 298 ? 205.679 56.623 16.827 1.00 33.39 ? 296 GLY B N 1 ATOM 5314 C CA . GLY B 1 298 ? 204.861 57.004 15.685 1.00 33.97 ? 296 GLY B CA 1 ATOM 5315 C C . GLY B 1 298 ? 205.398 56.336 14.437 1.00 40.86 ? 296 GLY B C 1 ATOM 5316 O O . GLY B 1 298 ? 204.638 55.777 13.634 1.00 38.43 ? 296 GLY B O 1 ATOM 5317 N N . TRP B 1 299 ? 206.736 56.388 14.290 1.00 41.11 ? 297 TRP B N 1 ATOM 5318 C CA . TRP B 1 299 ? 207.482 55.734 13.223 1.00 42.24 ? 297 TRP B CA 1 ATOM 5319 C C . TRP B 1 299 ? 207.621 54.275 13.688 1.00 46.23 ? 297 TRP B C 1 ATOM 5320 O O . TRP B 1 299 ? 207.155 53.367 12.993 1.00 45.07 ? 297 TRP B O 1 ATOM 5321 C CB . TRP B 1 299 ? 208.867 56.399 13.064 1.00 41.66 ? 297 TRP B CB 1 ATOM 5322 C CG . TRP B 1 299 ? 209.781 55.809 12.015 1.00 42.87 ? 297 TRP B CG 1 ATOM 5323 C CD1 . TRP B 1 299 ? 209.817 54.515 11.580 1.00 45.65 ? 297 TRP B CD1 1 ATOM 5324 C CD2 . TRP B 1 299 ? 210.875 56.474 11.374 1.00 42.75 ? 297 TRP B CD2 1 ATOM 5325 N NE1 . TRP B 1 299 ? 210.821 54.355 10.663 1.00 45.19 ? 297 TRP B NE1 1 ATOM 5326 C CE2 . TRP B 1 299 ? 211.478 55.544 10.504 1.00 46.72 ? 297 TRP B CE2 1 ATOM 5327 C CE3 . TRP B 1 299 ? 211.365 57.790 11.398 1.00 44.05 ? 297 TRP B CE3 1 ATOM 5328 C CZ2 . TRP B 1 299 ? 212.568 55.877 9.693 1.00 46.26 ? 297 TRP B CZ2 1 ATOM 5329 C CZ3 . TRP B 1 299 ? 212.467 58.108 10.626 1.00 45.57 ? 297 TRP B CZ3 1 ATOM 5330 C CH2 . TRP B 1 299 ? 213.038 57.168 9.762 1.00 46.25 ? 297 TRP B CH2 1 ATOM 5331 N N . GLY B 1 300 ? 208.209 54.091 14.879 1.00 43.52 ? 298 GLY B N 1 ATOM 5332 C CA . GLY B 1 300 ? 208.427 52.793 15.507 1.00 44.15 ? 298 GLY B CA 1 ATOM 5333 C C . GLY B 1 300 ? 209.110 51.803 14.589 1.00 49.99 ? 298 GLY B C 1 ATOM 5334 O O . GLY B 1 300 ? 210.200 52.074 14.066 1.00 49.00 ? 298 GLY B O 1 ATOM 5335 N N . ALA B 1 301 ? 208.427 50.680 14.333 1.00 47.26 ? 299 ALA B N 1 ATOM 5336 C CA . ALA B 1 301 ? 208.939 49.651 13.437 1.00 46.74 ? 299 ALA B CA 1 ATOM 5337 C C . ALA B 1 301 ? 207.979 49.402 12.275 1.00 48.30 ? 299 ALA B C 1 ATOM 5338 O O . ALA B 1 301 ? 207.918 48.290 11.748 1.00 48.17 ? 299 ALA B O 1 ATOM 5339 C CB . ALA B 1 301 ? 209.220 48.370 14.216 1.00 47.70 ? 299 ALA B CB 1 ATOM 5340 N N . LEU B 1 302 ? 207.252 50.456 11.861 1.00 44.53 ? 300 LEU B N 1 ATOM 5341 C CA . LEU B 1 302 ? 206.305 50.448 10.731 1.00 44.81 ? 300 LEU B CA 1 ATOM 5342 C C . LEU B 1 302 ? 207.043 50.381 9.399 1.00 51.11 ? 300 LEU B C 1 ATOM 5343 O O . LEU B 1 302 ? 207.823 51.289 9.095 1.00 50.41 ? 300 LEU B O 1 ATOM 5344 C CB . LEU B 1 302 ? 205.475 51.749 10.701 1.00 44.43 ? 300 LEU B CB 1 ATOM 5345 C CG . LEU B 1 302 ? 204.100 51.791 11.337 1.00 47.56 ? 300 LEU B CG 1 ATOM 5346 C CD1 . LEU B 1 302 ? 203.485 53.118 11.090 1.00 46.09 ? 300 LEU B CD1 1 ATOM 5347 C CD2 . LEU B 1 302 ? 203.169 50.700 10.777 1.00 49.36 ? 300 LEU B CD2 1 ATOM 5348 N N . GLU B 1 303 ? 206.746 49.362 8.573 1.00 50.03 ? 301 GLU B N 1 ATOM 5349 C CA . GLU B 1 303 ? 207.357 49.252 7.244 1.00 50.58 ? 301 GLU B CA 1 ATOM 5350 C C . GLU B 1 303 ? 206.809 50.327 6.252 1.00 54.33 ? 301 GLU B C 1 ATOM 5351 O O . GLU B 1 303 ? 207.580 50.813 5.428 1.00 53.29 ? 301 GLU B O 1 ATOM 5352 C CB . GLU B 1 303 ? 207.263 47.812 6.679 1.00 51.88 ? 301 GLU B CB 1 ATOM 5353 C CG . GLU B 1 303 ? 208.321 46.858 7.236 1.00 65.37 ? 301 GLU B CG 1 ATOM 5354 C CD . GLU B 1 303 ? 209.745 46.921 6.691 1.00 96.37 ? 301 GLU B CD 1 ATOM 5355 O OE1 . GLU B 1 303 ? 210.041 47.792 5.838 1.00 100.93 ? 301 GLU B OE1 1 ATOM 5356 O OE2 . GLU B 1 303 ? 210.570 46.079 7.116 1.00 87.56 ? 301 GLU B OE2 1 ATOM 5357 N N . GLU B 1 304 ? 205.512 50.732 6.376 1.00 51.47 ? 302 GLU B N 1 ATOM 5358 C CA . GLU B 1 304 ? 204.865 51.766 5.531 1.00 52.54 ? 302 GLU B CA 1 ATOM 5359 C C . GLU B 1 304 ? 205.554 53.124 5.583 1.00 57.64 ? 302 GLU B C 1 ATOM 5360 O O . GLU B 1 304 ? 205.493 53.877 4.603 1.00 57.99 ? 302 GLU B O 1 ATOM 5361 C CB . GLU B 1 304 ? 203.344 51.948 5.791 1.00 54.34 ? 302 GLU B CB 1 ATOM 5362 C CG . GLU B 1 304 ? 202.803 51.516 7.147 1.00 68.63 ? 302 GLU B CG 1 ATOM 5363 C CD . GLU B 1 304 ? 202.444 50.039 7.212 1.00 91.97 ? 302 GLU B CD 1 ATOM 5364 O OE1 . GLU B 1 304 ? 203.288 49.238 7.683 1.00 63.45 ? 302 GLU B OE1 1 ATOM 5365 O OE2 . GLU B 1 304 ? 201.336 49.679 6.749 1.00 90.80 ? 302 GLU B OE2 1 ATOM 5366 N N . VAL B 1 305 ? 206.208 53.428 6.722 1.00 53.01 ? 303 VAL B N 1 ATOM 5367 C CA . VAL B 1 305 ? 206.952 54.663 6.922 1.00 52.15 ? 303 VAL B CA 1 ATOM 5368 C C . VAL B 1 305 ? 208.191 54.686 5.996 1.00 59.00 ? 303 VAL B C 1 ATOM 5369 O O . VAL B 1 305 ? 208.377 55.650 5.245 1.00 61.27 ? 303 VAL B O 1 ATOM 5370 C CB . VAL B 1 305 ? 207.292 54.887 8.429 1.00 54.29 ? 303 VAL B CB 1 ATOM 5371 C CG1 . VAL B 1 305 ? 208.245 56.060 8.631 1.00 53.70 ? 303 VAL B CG1 1 ATOM 5372 C CG2 . VAL B 1 305 ? 206.029 55.094 9.251 1.00 53.55 ? 303 VAL B CG2 1 ATOM 5373 N N . VAL B 1 306 ? 208.995 53.613 6.023 1.00 54.37 ? 304 VAL B N 1 ATOM 5374 C CA . VAL B 1 306 ? 210.253 53.454 5.279 1.00 53.76 ? 304 VAL B CA 1 ATOM 5375 C C . VAL B 1 306 ? 210.101 52.934 3.827 1.00 57.42 ? 304 VAL B C 1 ATOM 5376 O O . VAL B 1 306 ? 211.069 53.007 3.059 1.00 56.29 ? 304 VAL B O 1 ATOM 5377 C CB . VAL B 1 306 ? 211.247 52.572 6.076 1.00 57.40 ? 304 VAL B CB 1 ATOM 5378 C CG1 . VAL B 1 306 ? 211.758 53.306 7.303 1.00 56.51 ? 304 VAL B CG1 1 ATOM 5379 C CG2 . VAL B 1 306 ? 210.619 51.224 6.462 1.00 57.30 ? 304 VAL B CG2 1 ATOM 5380 N N . ALA B 1 307 ? 208.909 52.418 3.455 1.00 55.12 ? 305 ALA B N 1 ATOM 5381 C CA . ALA B 1 307 ? 208.614 51.884 2.112 1.00 55.64 ? 305 ALA B CA 1 ATOM 5382 C C . ALA B 1 307 ? 208.877 52.888 0.967 1.00 61.19 ? 305 ALA B C 1 ATOM 5383 O O . ALA B 1 307 ? 208.289 53.974 0.927 1.00 61.09 ? 305 ALA B O 1 ATOM 5384 C CB . ALA B 1 307 ? 207.180 51.384 2.051 1.00 56.40 ? 305 ALA B CB 1 ATOM 5385 N N . GLY B 1 308 ? 209.793 52.522 0.078 1.00 58.55 ? 306 GLY B N 1 ATOM 5386 C CA . GLY B 1 308 ? 210.178 53.348 -1.061 1.00 58.74 ? 306 GLY B CA 1 ATOM 5387 C C . GLY B 1 308 ? 211.095 54.499 -0.701 1.00 63.50 ? 306 GLY B C 1 ATOM 5388 O O . GLY B 1 308 ? 211.412 55.325 -1.561 1.00 63.58 ? 306 GLY B O 1 ATOM 5389 N N . SER B 1 309 ? 211.531 54.572 0.571 1.00 59.72 ? 307 SER B N 1 ATOM 5390 C CA . SER B 1 309 ? 212.426 55.632 1.038 1.00 59.37 ? 307 SER B CA 1 ATOM 5391 C C . SER B 1 309 ? 213.552 55.040 1.893 1.00 62.17 ? 307 SER B C 1 ATOM 5392 O O . SER B 1 309 ? 214.268 55.774 2.577 1.00 62.62 ? 307 SER B O 1 ATOM 5393 C CB . SER B 1 309 ? 211.643 56.709 1.795 1.00 63.09 ? 307 SER B CB 1 ATOM 5394 O OG . SER B 1 309 ? 210.592 57.252 1.009 1.00 69.41 ? 307 SER B OG 1 ATOM 5395 N N . GLU B 1 310 ? 213.723 53.705 1.801 1.00 57.00 ? 308 GLU B N 1 ATOM 5396 C CA . GLU B 1 310 ? 214.694 52.859 2.518 1.00 55.52 ? 308 GLU B CA 1 ATOM 5397 C C . GLU B 1 310 ? 216.107 53.447 2.589 1.00 58.98 ? 308 GLU B C 1 ATOM 5398 O O . GLU B 1 310 ? 216.727 53.420 3.658 1.00 57.12 ? 308 GLU B O 1 ATOM 5399 C CB . GLU B 1 310 ? 214.736 51.448 1.913 1.00 55.92 ? 308 GLU B CB 1 ATOM 5400 C CG . GLU B 1 310 ? 213.402 50.722 1.880 1.00 60.83 ? 308 GLU B CG 1 ATOM 5401 C CD . GLU B 1 310 ? 212.539 50.926 0.647 1.00 80.19 ? 308 GLU B CD 1 ATOM 5402 O OE1 . GLU B 1 310 ? 212.927 51.719 -0.243 1.00 71.93 ? 308 GLU B OE1 1 ATOM 5403 O OE2 . GLU B 1 310 ? 211.460 50.294 0.576 1.00 76.98 ? 308 GLU B OE2 1 ATOM 5404 N N . GLY B 1 311 ? 216.582 53.977 1.459 1.00 56.31 ? 309 GLY B N 1 ATOM 5405 C CA . GLY B 1 311 ? 217.895 54.599 1.349 1.00 56.83 ? 309 GLY B CA 1 ATOM 5406 C C . GLY B 1 311 ? 218.059 55.735 2.333 1.00 62.32 ? 309 GLY B C 1 ATOM 5407 O O . GLY B 1 311 ? 218.982 55.721 3.160 1.00 62.05 ? 309 GLY B O 1 ATOM 5408 N N . ALA B 1 312 ? 217.099 56.685 2.289 1.00 59.97 ? 310 ALA B N 1 ATOM 5409 C CA . ALA B 1 312 ? 217.024 57.869 3.160 1.00 60.42 ? 310 ALA B CA 1 ATOM 5410 C C . ALA B 1 312 ? 216.813 57.522 4.653 1.00 63.59 ? 310 ALA B C 1 ATOM 5411 O O . ALA B 1 312 ? 217.083 58.350 5.517 1.00 62.80 ? 310 ALA B O 1 ATOM 5412 C CB . ALA B 1 312 ? 215.919 58.801 2.674 1.00 61.29 ? 310 ALA B CB 1 ATOM 5413 N N . ALA B 1 313 ? 216.359 56.293 4.938 1.00 60.52 ? 311 ALA B N 1 ATOM 5414 C CA . ALA B 1 313 ? 216.077 55.788 6.278 1.00 60.53 ? 311 ALA B CA 1 ATOM 5415 C C . ALA B 1 313 ? 217.214 54.988 6.917 1.00 66.01 ? 311 ALA B C 1 ATOM 5416 O O . ALA B 1 313 ? 217.135 54.720 8.116 1.00 65.47 ? 311 ALA B O 1 ATOM 5417 C CB . ALA B 1 313 ? 214.813 54.940 6.243 1.00 61.01 ? 311 ALA B CB 1 ATOM 5418 N N . GLU B 1 314 ? 218.251 54.580 6.138 1.00 63.60 ? 312 GLU B N 1 ATOM 5419 C CA . GLU B 1 314 ? 219.335 53.742 6.668 1.00 63.51 ? 312 GLU B CA 1 ATOM 5420 C C . GLU B 1 314 ? 220.059 54.356 7.858 1.00 66.72 ? 312 GLU B C 1 ATOM 5421 O O . GLU B 1 314 ? 220.313 55.561 7.881 1.00 66.74 ? 312 GLU B O 1 ATOM 5422 C CB . GLU B 1 314 ? 220.329 53.313 5.587 1.00 65.05 ? 312 GLU B CB 1 ATOM 5423 C CG . GLU B 1 314 ? 220.896 51.927 5.863 1.00 78.93 ? 312 GLU B CG 1 ATOM 5424 C CD . GLU B 1 314 ? 222.234 51.530 5.259 1.00 108.48 ? 312 GLU B CD 1 ATOM 5425 O OE1 . GLU B 1 314 ? 222.737 50.444 5.631 1.00 109.58 ? 312 GLU B OE1 1 ATOM 5426 O OE2 . GLU B 1 314 ? 222.777 52.282 4.416 1.00 102.17 ? 312 GLU B OE2 1 ATOM 5427 N N . GLY B 1 315 ? 220.319 53.516 8.855 1.00 62.27 ? 313 GLY B N 1 ATOM 5428 C CA . GLY B 1 315 ? 221.014 53.885 10.081 1.00 61.76 ? 313 GLY B CA 1 ATOM 5429 C C . GLY B 1 315 ? 220.135 54.430 11.187 1.00 64.82 ? 313 GLY B C 1 ATOM 5430 O O . GLY B 1 315 ? 220.605 54.563 12.319 1.00 65.19 ? 313 GLY B O 1 ATOM 5431 N N . ALA B 1 316 ? 218.854 54.746 10.869 1.00 59.74 ? 314 ALA B N 1 ATOM 5432 C CA . ALA B 1 316 ? 217.845 55.307 11.781 1.00 58.01 ? 314 ALA B CA 1 ATOM 5433 C C . ALA B 1 316 ? 217.564 54.444 12.978 1.00 57.67 ? 314 ALA B C 1 ATOM 5434 O O . ALA B 1 316 ? 217.339 53.246 12.832 1.00 56.58 ? 314 ALA B O 1 ATOM 5435 C CB . ALA B 1 316 ? 216.541 55.569 11.043 1.00 58.77 ? 314 ALA B CB 1 ATOM 5436 N N . ILE B 1 317 ? 217.551 55.079 14.156 1.00 52.51 ? 315 ILE B N 1 ATOM 5437 C CA . ILE B 1 317 ? 217.239 54.507 15.466 1.00 51.66 ? 315 ILE B CA 1 ATOM 5438 C C . ILE B 1 317 ? 215.771 54.845 15.781 1.00 53.55 ? 315 ILE B C 1 ATOM 5439 O O . ILE B 1 317 ? 215.372 56.012 15.686 1.00 53.02 ? 315 ILE B O 1 ATOM 5440 C CB . ILE B 1 317 ? 218.207 55.063 16.543 1.00 54.66 ? 315 ILE B CB 1 ATOM 5441 C CG1 . ILE B 1 317 ? 219.587 54.399 16.436 1.00 54.66 ? 315 ILE B CG1 1 ATOM 5442 C CG2 . ILE B 1 317 ? 217.620 54.948 17.975 1.00 55.35 ? 315 ILE B CG2 1 ATOM 5443 C CD1 . ILE B 1 317 ? 220.668 55.174 17.214 1.00 62.17 ? 315 ILE B CD1 1 ATOM 5444 N N . THR B 1 318 ? 214.961 53.827 16.112 1.00 47.82 ? 316 THR B N 1 ATOM 5445 C CA . THR B 1 318 ? 213.549 54.057 16.421 1.00 46.81 ? 316 THR B CA 1 ATOM 5446 C C . THR B 1 318 ? 213.128 53.396 17.749 1.00 50.15 ? 316 THR B C 1 ATOM 5447 O O . THR B 1 318 ? 213.733 52.415 18.186 1.00 49.66 ? 316 THR B O 1 ATOM 5448 C CB . THR B 1 318 ? 212.627 53.668 15.248 1.00 48.44 ? 316 THR B CB 1 ATOM 5449 O OG1 . THR B 1 318 ? 212.769 52.286 14.969 1.00 50.98 ? 316 THR B OG1 1 ATOM 5450 C CG2 . THR B 1 318 ? 212.858 54.483 13.981 1.00 43.20 ? 316 THR B CG2 1 ATOM 5451 N N . ILE B 1 319 ? 212.100 53.963 18.392 1.00 46.66 ? 317 ILE B N 1 ATOM 5452 C CA . ILE B 1 319 ? 211.534 53.461 19.642 1.00 46.70 ? 317 ILE B CA 1 ATOM 5453 C C . ILE B 1 319 ? 210.165 52.857 19.353 1.00 47.96 ? 317 ILE B C 1 ATOM 5454 O O . ILE B 1 319 ? 209.470 53.307 18.452 1.00 46.53 ? 317 ILE B O 1 ATOM 5455 C CB . ILE B 1 319 ? 211.399 54.581 20.705 1.00 50.73 ? 317 ILE B CB 1 ATOM 5456 C CG1 . ILE B 1 319 ? 212.674 55.450 20.836 1.00 51.71 ? 317 ILE B CG1 1 ATOM 5457 C CG2 . ILE B 1 319 ? 210.965 54.004 22.048 1.00 51.97 ? 317 ILE B CG2 1 ATOM 5458 C CD1 . ILE B 1 319 ? 213.721 54.954 21.837 1.00 61.73 ? 317 ILE B CD1 1 ATOM 5459 N N . GLU B 1 320 ? 209.782 51.848 20.128 1.00 44.26 ? 318 GLU B N 1 ATOM 5460 C CA . GLU B 1 320 ? 208.487 51.184 20.042 1.00 44.34 ? 318 GLU B CA 1 ATOM 5461 C C . GLU B 1 320 ? 208.272 50.450 21.336 1.00 47.41 ? 318 GLU B C 1 ATOM 5462 O O . GLU B 1 320 ? 209.203 49.864 21.869 1.00 47.60 ? 318 GLU B O 1 ATOM 5463 C CB . GLU B 1 320 ? 208.381 50.236 18.820 1.00 45.94 ? 318 GLU B CB 1 ATOM 5464 C CG . GLU B 1 320 ? 206.974 49.706 18.539 1.00 59.56 ? 318 GLU B CG 1 ATOM 5465 C CD . GLU B 1 320 ? 205.761 50.637 18.422 1.00 68.92 ? 318 GLU B CD 1 ATOM 5466 O OE1 . GLU B 1 320 ? 205.392 50.993 17.277 1.00 68.33 ? 318 GLU B OE1 1 ATOM 5467 O OE2 . GLU B 1 320 ? 205.088 50.863 19.455 1.00 33.96 ? 318 GLU B OE2 1 ATOM 5468 N N . LEU B 1 321 ? 207.055 50.518 21.858 1.00 43.01 ? 319 LEU B N 1 ATOM 5469 C CA . LEU B 1 321 ? 206.639 49.904 23.108 1.00 41.83 ? 319 LEU B CA 1 ATOM 5470 C C . LEU B 1 321 ? 206.811 48.405 23.012 1.00 48.08 ? 319 LEU B C 1 ATOM 5471 O O . LEU B 1 321 ? 206.386 47.794 22.028 1.00 47.60 ? 319 LEU B O 1 ATOM 5472 C CB . LEU B 1 321 ? 205.182 50.285 23.408 1.00 41.34 ? 319 LEU B CB 1 ATOM 5473 C CG . LEU B 1 321 ? 204.900 51.721 23.951 1.00 45.12 ? 319 LEU B CG 1 ATOM 5474 C CD1 . LEU B 1 321 ? 205.201 52.821 22.934 1.00 45.26 ? 319 LEU B CD1 1 ATOM 5475 C CD2 . LEU B 1 321 ? 203.465 51.872 24.220 1.00 46.97 ? 319 LEU B CD2 1 ATOM 5476 N N . ALA B 1 322 ? 207.533 47.838 23.995 1.00 47.10 ? 320 ALA B N 1 ATOM 5477 C CA . ALA B 1 322 ? 207.842 46.414 24.091 1.00 48.09 ? 320 ALA B CA 1 ATOM 5478 C C . ALA B 1 322 ? 206.572 45.567 24.119 1.00 52.71 ? 320 ALA B C 1 ATOM 5479 O O . ALA B 1 322 ? 205.708 45.736 24.984 1.00 50.25 ? 320 ALA B O 1 ATOM 5480 C CB . ALA B 1 322 ? 208.688 46.146 25.326 1.00 49.11 ? 320 ALA B CB 1 ATOM 5481 N N . SER B 1 323 ? 206.458 44.678 23.138 1.00 52.78 ? 321 SER B N 1 ATOM 5482 C CA . SER B 1 323 ? 205.293 43.813 22.967 1.00 54.33 ? 321 SER B CA 1 ATOM 5483 C C . SER B 1 323 ? 205.697 42.467 22.381 1.00 59.72 ? 321 SER B C 1 ATOM 5484 O O . SER B 1 323 ? 206.797 42.330 21.828 1.00 58.03 ? 321 SER B O 1 ATOM 5485 C CB . SER B 1 323 ? 204.267 44.493 22.063 1.00 58.87 ? 321 SER B CB 1 ATOM 5486 O OG . SER B 1 323 ? 204.914 44.994 20.904 1.00 68.44 ? 321 SER B OG 1 ATOM 5487 N N . TYR B 1 324 ? 204.793 41.481 22.503 1.00 58.50 ? 322 TYR B N 1 ATOM 5488 C CA . TYR B 1 324 ? 205.011 40.117 22.039 1.00 59.52 ? 322 TYR B CA 1 ATOM 5489 C C . TYR B 1 324 ? 203.990 39.651 21.006 1.00 61.66 ? 322 TYR B C 1 ATOM 5490 O O . TYR B 1 324 ? 202.842 40.101 21.031 1.00 60.24 ? 322 TYR B O 1 ATOM 5491 C CB . TYR B 1 324 ? 205.058 39.146 23.232 1.00 61.99 ? 322 TYR B CB 1 ATOM 5492 C CG . TYR B 1 324 ? 206.246 39.384 24.128 1.00 66.92 ? 322 TYR B CG 1 ATOM 5493 C CD1 . TYR B 1 324 ? 207.548 39.180 23.667 1.00 68.68 ? 322 TYR B CD1 1 ATOM 5494 C CD2 . TYR B 1 324 ? 206.078 39.822 25.438 1.00 69.82 ? 322 TYR B CD2 1 ATOM 5495 C CE1 . TYR B 1 324 ? 208.652 39.399 24.492 1.00 69.45 ? 322 TYR B CE1 1 ATOM 5496 C CE2 . TYR B 1 324 ? 207.176 40.026 26.281 1.00 71.71 ? 322 TYR B CE2 1 ATOM 5497 C CZ . TYR B 1 324 ? 208.461 39.820 25.801 1.00 80.43 ? 322 TYR B CZ 1 ATOM 5498 O OH . TYR B 1 324 ? 209.535 40.035 26.634 1.00 84.26 ? 322 TYR B OH 1 ATOM 5499 N N . PRO B 1 325 ? 204.378 38.719 20.109 1.00 57.92 ? 323 PRO B N 1 ATOM 5500 C CA . PRO B 1 325 ? 203.408 38.215 19.130 1.00 57.14 ? 323 PRO B CA 1 ATOM 5501 C C . PRO B 1 325 ? 202.357 37.346 19.811 1.00 57.12 ? 323 PRO B C 1 ATOM 5502 O O . PRO B 1 325 ? 202.659 36.698 20.812 1.00 57.89 ? 323 PRO B O 1 ATOM 5503 C CB . PRO B 1 325 ? 204.277 37.368 18.194 1.00 59.17 ? 323 PRO B CB 1 ATOM 5504 C CG . PRO B 1 325 ? 205.381 36.847 19.089 1.00 63.85 ? 323 PRO B CG 1 ATOM 5505 C CD . PRO B 1 325 ? 205.692 38.053 19.949 1.00 59.74 ? 323 PRO B CD 1 ATOM 5506 N N . ILE B 1 326 ? 201.129 37.347 19.278 1.00 48.70 ? 324 ILE B N 1 ATOM 5507 C CA . ILE B 1 326 ? 200.030 36.514 19.753 1.00 45.91 ? 324 ILE B CA 1 ATOM 5508 C C . ILE B 1 326 ? 199.723 35.654 18.546 1.00 50.15 ? 324 ILE B C 1 ATOM 5509 O O . ILE B 1 326 ? 199.121 36.129 17.581 1.00 51.95 ? 324 ILE B O 1 ATOM 5510 C CB . ILE B 1 326 ? 198.810 37.336 20.292 1.00 47.10 ? 324 ILE B CB 1 ATOM 5511 C CG1 . ILE B 1 326 ? 199.207 38.191 21.511 1.00 45.79 ? 324 ILE B CG1 1 ATOM 5512 C CG2 . ILE B 1 326 ? 197.614 36.429 20.624 1.00 46.13 ? 324 ILE B CG2 1 ATOM 5513 C CD1 . ILE B 1 326 ? 198.632 39.558 21.529 1.00 39.11 ? 324 ILE B CD1 1 ATOM 5514 N N . SER B 1 327 ? 200.248 34.429 18.552 1.00 46.24 ? 325 SER B N 1 ATOM 5515 C CA . SER B 1 327 ? 200.124 33.439 17.473 1.00 45.88 ? 325 SER B CA 1 ATOM 5516 C C . SER B 1 327 ? 198.665 33.180 17.097 1.00 46.37 ? 325 SER B C 1 ATOM 5517 O O . SER B 1 327 ? 198.342 33.082 15.911 1.00 45.31 ? 325 SER B O 1 ATOM 5518 C CB . SER B 1 327 ? 200.812 32.134 17.870 1.00 52.30 ? 325 SER B CB 1 ATOM 5519 O OG . SER B 1 327 ? 202.172 32.372 18.204 1.00 68.77 ? 325 SER B OG 1 ATOM 5520 N N . ASP B 1 328 ? 197.786 33.097 18.109 1.00 41.78 ? 326 ASP B N 1 ATOM 5521 C CA . ASP B 1 328 ? 196.358 32.885 17.924 1.00 40.96 ? 326 ASP B CA 1 ATOM 5522 C C . ASP B 1 328 ? 195.762 34.070 17.149 1.00 42.16 ? 326 ASP B C 1 ATOM 5523 O O . ASP B 1 328 ? 194.940 33.848 16.254 1.00 42.89 ? 326 ASP B O 1 ATOM 5524 C CB . ASP B 1 328 ? 195.663 32.676 19.282 1.00 43.48 ? 326 ASP B CB 1 ATOM 5525 C CG . ASP B 1 328 ? 195.925 31.330 19.935 1.00 63.75 ? 326 ASP B CG 1 ATOM 5526 O OD1 . ASP B 1 328 ? 196.204 30.350 19.198 1.00 68.45 ? 326 ASP B OD1 1 ATOM 5527 O OD2 . ASP B 1 328 ? 195.768 31.229 21.171 1.00 69.81 ? 326 ASP B OD2 1 ATOM 5528 N N . PHE B 1 329 ? 196.235 35.316 17.431 1.00 33.67 ? 327 PHE B N 1 ATOM 5529 C CA . PHE B 1 329 ? 195.763 36.453 16.664 1.00 31.76 ? 327 PHE B CA 1 ATOM 5530 C C . PHE B 1 329 ? 196.199 36.303 15.201 1.00 38.10 ? 327 PHE B C 1 ATOM 5531 O O . PHE B 1 329 ? 195.354 36.427 14.305 1.00 38.38 ? 327 PHE B O 1 ATOM 5532 C CB . PHE B 1 329 ? 196.175 37.815 17.250 1.00 31.66 ? 327 PHE B CB 1 ATOM 5533 C CG . PHE B 1 329 ? 195.686 38.953 16.370 1.00 30.12 ? 327 PHE B CG 1 ATOM 5534 C CD1 . PHE B 1 329 ? 194.324 39.195 16.210 1.00 30.51 ? 327 PHE B CD1 1 ATOM 5535 C CD2 . PHE B 1 329 ? 196.584 39.718 15.633 1.00 28.53 ? 327 PHE B CD2 1 ATOM 5536 C CE1 . PHE B 1 329 ? 193.877 40.210 15.363 1.00 30.13 ? 327 PHE B CE1 1 ATOM 5537 C CE2 . PHE B 1 329 ? 196.137 40.730 14.794 1.00 30.03 ? 327 PHE B CE2 1 ATOM 5538 C CZ . PHE B 1 329 ? 194.785 40.958 14.655 1.00 28.85 ? 327 PHE B CZ 1 ATOM 5539 N N . ALA B 1 330 ? 197.493 35.985 14.976 1.00 34.42 ? 328 ALA B N 1 ATOM 5540 C CA . ALA B 1 330 ? 198.063 35.737 13.648 1.00 34.55 ? 328 ALA B CA 1 ATOM 5541 C C . ALA B 1 330 ? 197.224 34.772 12.805 1.00 38.88 ? 328 ALA B C 1 ATOM 5542 O O . ALA B 1 330 ? 196.841 35.109 11.683 1.00 38.75 ? 328 ALA B O 1 ATOM 5543 C CB . ALA B 1 330 ? 199.482 35.209 13.776 1.00 35.16 ? 328 ALA B CB 1 ATOM 5544 N N . SER B 1 331 ? 196.906 33.599 13.370 1.00 35.45 ? 329 SER B N 1 ATOM 5545 C CA . SER B 1 331 ? 196.108 32.557 12.721 1.00 34.64 ? 329 SER B CA 1 ATOM 5546 C C . SER B 1 331 ? 194.721 33.095 12.340 1.00 34.83 ? 329 SER B C 1 ATOM 5547 O O . SER B 1 331 ? 194.274 32.883 11.220 1.00 33.79 ? 329 SER B O 1 ATOM 5548 C CB . SER B 1 331 ? 195.992 31.333 13.637 1.00 38.92 ? 329 SER B CB 1 ATOM 5549 O OG . SER B 1 331 ? 195.289 31.607 14.846 1.00 50.55 ? 329 SER B OG 1 ATOM 5550 N N . TYR B 1 332 ? 194.045 33.751 13.307 1.00 29.71 ? 330 TYR B N 1 ATOM 5551 C CA . TYR B 1 332 ? 192.730 34.367 13.181 1.00 28.29 ? 330 TYR B CA 1 ATOM 5552 C C . TYR B 1 332 ? 192.690 35.401 12.021 1.00 30.88 ? 330 TYR B C 1 ATOM 5553 O O . TYR B 1 332 ? 191.773 35.382 11.198 1.00 28.58 ? 330 TYR B O 1 ATOM 5554 C CB . TYR B 1 332 ? 192.349 35.023 14.529 1.00 28.32 ? 330 TYR B CB 1 ATOM 5555 C CG . TYR B 1 332 ? 191.251 36.054 14.416 1.00 29.39 ? 330 TYR B CG 1 ATOM 5556 C CD1 . TYR B 1 332 ? 189.918 35.670 14.314 1.00 30.67 ? 330 TYR B CD1 1 ATOM 5557 C CD2 . TYR B 1 332 ? 191.549 37.424 14.357 1.00 29.69 ? 330 TYR B CD2 1 ATOM 5558 C CE1 . TYR B 1 332 ? 188.901 36.617 14.197 1.00 33.39 ? 330 TYR B CE1 1 ATOM 5559 C CE2 . TYR B 1 332 ? 190.538 38.380 14.216 1.00 29.51 ? 330 TYR B CE2 1 ATOM 5560 C CZ . TYR B 1 332 ? 189.215 37.970 14.140 1.00 38.25 ? 330 TYR B CZ 1 ATOM 5561 O OH . TYR B 1 332 ? 188.191 38.880 14.007 1.00 39.95 ? 330 TYR B OH 1 ATOM 5562 N N . PHE B 1 333 ? 193.659 36.320 12.011 1.00 28.30 ? 331 PHE B N 1 ATOM 5563 C CA . PHE B 1 333 ? 193.739 37.355 11.009 1.00 29.07 ? 331 PHE B CA 1 ATOM 5564 C C . PHE B 1 333 ? 193.992 36.787 9.602 1.00 34.13 ? 331 PHE B C 1 ATOM 5565 O O . PHE B 1 333 ? 193.317 37.185 8.645 1.00 34.30 ? 331 PHE B O 1 ATOM 5566 C CB . PHE B 1 333 ? 194.770 38.422 11.399 1.00 30.92 ? 331 PHE B CB 1 ATOM 5567 C CG . PHE B 1 333 ? 194.580 39.667 10.571 1.00 33.04 ? 331 PHE B CG 1 ATOM 5568 C CD1 . PHE B 1 333 ? 193.615 40.612 10.914 1.00 36.64 ? 331 PHE B CD1 1 ATOM 5569 C CD2 . PHE B 1 333 ? 195.324 39.873 9.414 1.00 34.62 ? 331 PHE B CD2 1 ATOM 5570 C CE1 . PHE B 1 333 ? 193.400 41.741 10.112 1.00 37.21 ? 331 PHE B CE1 1 ATOM 5571 C CE2 . PHE B 1 333 ? 195.124 41.010 8.629 1.00 37.42 ? 331 PHE B CE2 1 ATOM 5572 C CZ . PHE B 1 333 ? 194.155 41.934 8.978 1.00 35.37 ? 331 PHE B CZ 1 ATOM 5573 N N . GLN B 1 334 ? 194.907 35.854 9.514 1.00 29.51 ? 332 GLN B N 1 ATOM 5574 C CA . GLN B 1 334 ? 195.229 35.235 8.270 1.00 28.56 ? 332 GLN B CA 1 ATOM 5575 C C . GLN B 1 334 ? 194.114 34.369 7.776 1.00 32.65 ? 332 GLN B C 1 ATOM 5576 O O . GLN B 1 334 ? 194.105 33.980 6.659 1.00 35.32 ? 332 GLN B O 1 ATOM 5577 C CB . GLN B 1 334 ? 196.527 34.468 8.398 1.00 29.68 ? 332 GLN B CB 1 ATOM 5578 C CG . GLN B 1 334 ? 197.729 35.371 8.314 1.00 39.09 ? 332 GLN B CG 1 ATOM 5579 C CD . GLN B 1 334 ? 199.046 34.651 8.273 1.00 57.15 ? 332 GLN B CD 1 ATOM 5580 O OE1 . GLN B 1 334 ? 199.506 34.149 9.262 1.00 46.72 ? 332 GLN B OE1 1 ATOM 5581 N NE2 . GLN B 1 334 ? 199.668 34.631 7.121 1.00 57.73 ? 332 GLN B NE2 1 ATOM 5582 N N . SER B 1 335 ? 193.148 34.096 8.618 1.00 27.72 ? 333 SER B N 1 ATOM 5583 C CA . SER B 1 335 ? 192.033 33.280 8.244 1.00 27.50 ? 333 SER B CA 1 ATOM 5584 C C . SER B 1 335 ? 190.877 34.087 7.720 1.00 30.12 ? 333 SER B C 1 ATOM 5585 O O . SER B 1 335 ? 189.931 33.537 7.219 1.00 30.82 ? 333 SER B O 1 ATOM 5586 C CB . SER B 1 335 ? 191.616 32.401 9.410 1.00 31.84 ? 333 SER B CB 1 ATOM 5587 O OG . SER B 1 335 ? 190.680 33.037 10.247 1.00 44.88 ? 333 SER B OG 1 ATOM 5588 N N . LEU B 1 336 ? 190.968 35.396 7.799 1.00 26.01 ? 334 LEU B N 1 ATOM 5589 C CA . LEU B 1 336 ? 189.872 36.247 7.411 1.00 26.45 ? 334 LEU B CA 1 ATOM 5590 C C . LEU B 1 336 ? 189.690 36.352 5.902 1.00 33.59 ? 334 LEU B C 1 ATOM 5591 O O . LEU B 1 336 ? 190.631 36.363 5.158 1.00 30.80 ? 334 LEU B O 1 ATOM 5592 C CB . LEU B 1 336 ? 189.972 37.620 8.064 1.00 25.53 ? 334 LEU B CB 1 ATOM 5593 C CG . LEU B 1 336 ? 190.010 37.802 9.572 1.00 27.41 ? 334 LEU B CG 1 ATOM 5594 C CD1 . LEU B 1 336 ? 190.554 39.131 9.987 1.00 26.42 ? 334 LEU B CD1 1 ATOM 5595 C CD2 . LEU B 1 336 ? 188.699 37.573 10.231 1.00 25.59 ? 334 LEU B CD2 1 ATOM 5596 N N . ASP B 1 337 ? 188.430 36.451 5.506 1.00 33.90 ? 335 ASP B N 1 ATOM 5597 C CA . ASP B 1 337 ? 187.934 36.187 4.188 1.00 34.93 ? 335 ASP B CA 1 ATOM 5598 C C . ASP B 1 337 ? 186.834 37.136 3.797 1.00 39.44 ? 335 ASP B C 1 ATOM 5599 O O . ASP B 1 337 ? 185.867 37.229 4.477 1.00 37.96 ? 335 ASP B O 1 ATOM 5600 C CB . ASP B 1 337 ? 187.308 34.819 4.238 1.00 37.46 ? 335 ASP B CB 1 ATOM 5601 C CG . ASP B 1 337 ? 187.130 34.214 2.917 1.00 46.43 ? 335 ASP B CG 1 ATOM 5602 O OD1 . ASP B 1 337 ? 186.309 34.682 2.155 1.00 45.37 ? 335 ASP B OD1 1 ATOM 5603 O OD2 . ASP B 1 337 ? 187.801 33.236 2.664 1.00 56.91 ? 335 ASP B OD2 1 ATOM 5604 N N . PRO B 1 338 ? 187.020 37.834 2.597 1.00 39.68 ? 336 PRO B N 1 ATOM 5605 C CA . PRO B 1 338 ? 185.897 38.713 2.228 1.00 40.54 ? 336 PRO B CA 1 ATOM 5606 C C . PRO B 1 338 ? 184.501 38.127 2.265 1.00 46.01 ? 336 PRO B C 1 ATOM 5607 O O . PRO B 1 338 ? 183.562 38.863 2.118 1.00 45.02 ? 336 PRO B O 1 ATOM 5608 C CB . PRO B 1 338 ? 186.185 39.060 0.795 1.00 41.80 ? 336 PRO B CB 1 ATOM 5609 C CG . PRO B 1 338 ? 187.608 39.189 0.766 1.00 46.46 ? 336 PRO B CG 1 ATOM 5610 C CD . PRO B 1 338 ? 188.084 38.009 1.492 1.00 41.95 ? 336 PRO B CD 1 ATOM 5611 N N . TRP B 1 339 ? 184.361 36.833 2.434 1.00 43.16 ? 337 TRP B N 1 ATOM 5612 C CA . TRP B 1 339 ? 183.074 36.219 2.328 1.00 42.93 ? 337 TRP B CA 1 ATOM 5613 C C . TRP B 1 339 ? 182.631 35.745 3.655 1.00 48.60 ? 337 TRP B C 1 ATOM 5614 O O . TRP B 1 339 ? 181.467 35.540 3.856 1.00 51.09 ? 337 TRP B O 1 ATOM 5615 C CB . TRP B 1 339 ? 183.119 35.099 1.327 1.00 41.39 ? 337 TRP B CB 1 ATOM 5616 C CG . TRP B 1 339 ? 183.135 35.609 -0.022 1.00 42.09 ? 337 TRP B CG 1 ATOM 5617 C CD1 . TRP B 1 339 ? 182.076 35.842 -0.787 1.00 45.00 ? 337 TRP B CD1 1 ATOM 5618 C CD2 . TRP B 1 339 ? 184.271 36.022 -0.769 1.00 41.96 ? 337 TRP B CD2 1 ATOM 5619 N NE1 . TRP B 1 339 ? 182.456 36.370 -1.967 1.00 44.52 ? 337 TRP B NE1 1 ATOM 5620 C CE2 . TRP B 1 339 ? 183.810 36.491 -1.984 1.00 45.60 ? 337 TRP B CE2 1 ATOM 5621 C CE3 . TRP B 1 339 ? 185.638 36.039 -0.524 1.00 43.33 ? 337 TRP B CE3 1 ATOM 5622 C CZ2 . TRP B 1 339 ? 184.651 36.967 -2.961 1.00 44.61 ? 337 TRP B CZ2 1 ATOM 5623 C CZ3 . TRP B 1 339 ? 186.467 36.504 -1.489 1.00 44.53 ? 337 TRP B CZ3 1 ATOM 5624 C CH2 . TRP B 1 339 ? 185.979 36.964 -2.693 1.00 45.01 ? 337 TRP B CH2 1 ATOM 5625 N N . ASN B 1 340 ? 183.552 35.611 4.585 1.00 43.57 ? 338 ASN B N 1 ATOM 5626 C CA . ASN B 1 340 ? 183.167 35.277 5.931 1.00 43.30 ? 338 ASN B CA 1 ATOM 5627 C C . ASN B 1 340 ? 183.268 36.413 6.913 1.00 44.61 ? 338 ASN B C 1 ATOM 5628 O O . ASN B 1 340 ? 182.935 36.259 8.046 1.00 44.32 ? 338 ASN B O 1 ATOM 5629 C CB . ASN B 1 340 ? 183.804 33.973 6.430 1.00 44.40 ? 338 ASN B CB 1 ATOM 5630 C CG . ASN B 1 340 ? 185.316 33.995 6.451 1.00 72.10 ? 338 ASN B CG 1 ATOM 5631 O OD1 . ASN B 1 340 ? 185.954 34.929 6.914 1.00 63.85 ? 338 ASN B OD1 1 ATOM 5632 N ND2 . ASN B 1 340 ? 185.889 32.919 6.005 1.00 61.24 ? 338 ASN B ND2 1 ATOM 5633 N N . ASN B 1 341 ? 183.677 37.574 6.450 1.00 38.04 ? 339 ASN B N 1 ATOM 5634 C CA . ASN B 1 341 ? 183.815 38.711 7.321 1.00 36.88 ? 339 ASN B CA 1 ATOM 5635 C C . ASN B 1 341 ? 182.821 39.842 7.116 1.00 41.42 ? 339 ASN B C 1 ATOM 5636 O O . ASN B 1 341 ? 183.168 40.967 6.977 1.00 42.49 ? 339 ASN B O 1 ATOM 5637 C CB . ASN B 1 341 ? 185.245 39.210 7.302 1.00 33.43 ? 339 ASN B CB 1 ATOM 5638 C CG . ASN B 1 341 ? 185.675 39.746 8.619 1.00 47.79 ? 339 ASN B CG 1 ATOM 5639 O OD1 . ASN B 1 341 ? 184.925 39.757 9.561 1.00 42.76 ? 339 ASN B OD1 1 ATOM 5640 N ND2 . ASN B 1 341 ? 186.869 40.197 8.685 1.00 37.63 ? 339 ASN B ND2 1 ATOM 5641 N N . SER B 1 342 ? 181.562 39.499 7.141 1.00 37.06 ? 340 SER B N 1 ATOM 5642 C CA . SER B 1 342 ? 180.439 40.427 6.996 1.00 36.65 ? 340 SER B CA 1 ATOM 5643 C C . SER B 1 342 ? 180.306 41.393 8.180 1.00 40.52 ? 340 SER B C 1 ATOM 5644 O O . SER B 1 342 ? 179.801 42.509 8.009 1.00 40.93 ? 340 SER B O 1 ATOM 5645 C CB . SER B 1 342 ? 179.145 39.631 6.826 1.00 42.14 ? 340 SER B CB 1 ATOM 5646 O OG . SER B 1 342 ? 179.095 38.863 5.628 1.00 57.16 ? 340 SER B OG 1 ATOM 5647 N N . ARG B 1 343 ? 180.694 40.929 9.394 1.00 35.90 ? 341 ARG B N 1 ATOM 5648 C CA . ARG B 1 343 ? 180.609 41.693 10.637 1.00 33.49 ? 341 ARG B CA 1 ATOM 5649 C C . ARG B 1 343 ? 181.501 42.940 10.622 1.00 35.66 ? 341 ARG B C 1 ATOM 5650 O O . ARG B 1 343 ? 181.183 43.885 11.325 1.00 35.47 ? 341 ARG B O 1 ATOM 5651 C CB . ARG B 1 343 ? 180.861 40.809 11.870 1.00 27.36 ? 341 ARG B CB 1 ATOM 5652 C CG . ARG B 1 343 ? 182.315 40.419 12.102 1.00 26.77 ? 341 ARG B CG 1 ATOM 5653 C CD . ARG B 1 343 ? 182.426 39.779 13.457 1.00 23.12 ? 341 ARG B CD 1 ATOM 5654 N NE . ARG B 1 343 ? 183.804 39.419 13.765 1.00 23.08 ? 341 ARG B NE 1 ATOM 5655 C CZ . ARG B 1 343 ? 184.176 38.815 14.888 1.00 31.25 ? 341 ARG B CZ 1 ATOM 5656 N NH1 . ARG B 1 343 ? 183.269 38.484 15.800 1.00 12.88 ? 341 ARG B NH1 1 ATOM 5657 N NH2 . ARG B 1 343 ? 185.460 38.510 15.097 1.00 4.41 ? 341 ARG B NH2 1 ATOM 5658 N N . ASN B 1 344 ? 182.584 42.951 9.825 1.00 31.19 ? 342 ASN B N 1 ATOM 5659 C CA . ASN B 1 344 ? 183.454 44.125 9.695 1.00 31.51 ? 342 ASN B CA 1 ATOM 5660 C C . ASN B 1 344 ? 183.035 44.933 8.406 1.00 36.40 ? 342 ASN B C 1 ATOM 5661 O O . ASN B 1 344 ? 183.344 44.506 7.276 1.00 37.86 ? 342 ASN B O 1 ATOM 5662 C CB . ASN B 1 344 ? 184.939 43.709 9.665 1.00 28.12 ? 342 ASN B CB 1 ATOM 5663 C CG . ASN B 1 344 ? 185.884 44.856 9.426 1.00 33.06 ? 342 ASN B CG 1 ATOM 5664 O OD1 . ASN B 1 344 ? 185.497 46.009 9.171 1.00 34.79 ? 342 ASN B OD1 1 ATOM 5665 N ND2 . ASN B 1 344 ? 187.152 44.583 9.567 1.00 14.27 ? 342 ASN B ND2 1 ATOM 5666 N N . PRO B 1 345 ? 182.346 46.091 8.548 1.00 28.97 ? 343 PRO B N 1 ATOM 5667 C CA . PRO B 1 345 ? 181.889 46.823 7.355 1.00 27.41 ? 343 PRO B CA 1 ATOM 5668 C C . PRO B 1 345 ? 182.971 47.313 6.405 1.00 31.14 ? 343 PRO B C 1 ATOM 5669 O O . PRO B 1 345 ? 182.652 47.561 5.247 1.00 32.40 ? 343 PRO B O 1 ATOM 5670 C CB . PRO B 1 345 ? 181.096 47.994 7.942 1.00 28.29 ? 343 PRO B CB 1 ATOM 5671 C CG . PRO B 1 345 ? 181.649 48.174 9.293 1.00 32.72 ? 343 PRO B CG 1 ATOM 5672 C CD . PRO B 1 345 ? 181.899 46.773 9.772 1.00 28.96 ? 343 PRO B CD 1 ATOM 5673 N N . TRP B 1 346 ? 184.221 47.471 6.881 1.00 25.39 ? 344 TRP B N 1 ATOM 5674 C CA . TRP B 1 346 ? 185.327 47.995 6.082 1.00 24.52 ? 344 TRP B CA 1 ATOM 5675 C C . TRP B 1 346 ? 186.262 46.916 5.489 1.00 28.86 ? 344 TRP B C 1 ATOM 5676 O O . TRP B 1 346 ? 187.196 47.260 4.759 1.00 29.30 ? 344 TRP B O 1 ATOM 5677 C CB . TRP B 1 346 ? 186.156 48.969 6.936 1.00 23.32 ? 344 TRP B CB 1 ATOM 5678 C CG . TRP B 1 346 ? 185.385 50.066 7.614 1.00 24.48 ? 344 TRP B CG 1 ATOM 5679 C CD1 . TRP B 1 346 ? 184.985 51.254 7.066 1.00 27.25 ? 344 TRP B CD1 1 ATOM 5680 C CD2 . TRP B 1 346 ? 184.996 50.110 9.000 1.00 24.37 ? 344 TRP B CD2 1 ATOM 5681 N NE1 . TRP B 1 346 ? 184.316 52.009 8.007 1.00 26.46 ? 344 TRP B NE1 1 ATOM 5682 C CE2 . TRP B 1 346 ? 184.345 51.348 9.214 1.00 27.77 ? 344 TRP B CE2 1 ATOM 5683 C CE3 . TRP B 1 346 ? 185.158 49.231 10.092 1.00 25.07 ? 344 TRP B CE3 1 ATOM 5684 C CZ2 . TRP B 1 346 ? 183.863 51.730 10.473 1.00 26.27 ? 344 TRP B CZ2 1 ATOM 5685 C CZ3 . TRP B 1 346 ? 184.702 49.626 11.339 1.00 25.68 ? 344 TRP B CZ3 1 ATOM 5686 C CH2 . TRP B 1 346 ? 184.031 50.843 11.512 1.00 26.11 ? 344 TRP B CH2 1 ATOM 5687 N N . PHE B 1 347 ? 186.050 45.628 5.817 1.00 24.69 ? 345 PHE B N 1 ATOM 5688 C CA . PHE B 1 347 ? 186.944 44.580 5.343 1.00 24.17 ? 345 PHE B CA 1 ATOM 5689 C C . PHE B 1 347 ? 186.933 44.380 3.825 1.00 30.63 ? 345 PHE B C 1 ATOM 5690 O O . PHE B 1 347 ? 188.005 44.129 3.253 1.00 32.16 ? 345 PHE B O 1 ATOM 5691 C CB . PHE B 1 347 ? 186.695 43.269 6.065 1.00 25.24 ? 345 PHE B CB 1 ATOM 5692 C CG . PHE B 1 347 ? 187.834 42.283 5.928 1.00 25.00 ? 345 PHE B CG 1 ATOM 5693 C CD1 . PHE B 1 347 ? 188.924 42.326 6.802 1.00 27.18 ? 345 PHE B CD1 1 ATOM 5694 C CD2 . PHE B 1 347 ? 187.785 41.270 4.976 1.00 24.10 ? 345 PHE B CD2 1 ATOM 5695 C CE1 . PHE B 1 347 ? 189.963 41.400 6.695 1.00 27.22 ? 345 PHE B CE1 1 ATOM 5696 C CE2 . PHE B 1 347 ? 188.818 40.336 4.874 1.00 26.43 ? 345 PHE B CE2 1 ATOM 5697 C CZ . PHE B 1 347 ? 189.901 40.410 5.725 1.00 25.20 ? 345 PHE B CZ 1 ATOM 5698 N N . ARG B 1 348 ? 185.758 44.512 3.164 1.00 25.55 ? 346 ARG B N 1 ATOM 5699 C CA . ARG B 1 348 ? 185.702 44.359 1.706 1.00 24.70 ? 346 ARG B CA 1 ATOM 5700 C C . ARG B 1 348 ? 186.498 45.512 1.062 1.00 29.26 ? 346 ARG B C 1 ATOM 5701 O O . ARG B 1 348 ? 187.305 45.267 0.151 1.00 29.74 ? 346 ARG B O 1 ATOM 5702 C CB . ARG B 1 348 ? 184.251 44.200 1.196 1.00 24.50 ? 346 ARG B CB 1 ATOM 5703 C CG . ARG B 1 348 ? 183.762 42.732 1.246 1.00 35.79 ? 346 ARG B CG 1 ATOM 5704 C CD . ARG B 1 348 ? 182.335 42.454 0.765 1.00 39.11 ? 346 ARG B CD 1 ATOM 5705 N NE . ARG B 1 348 ? 182.251 41.988 -0.633 1.00 51.97 ? 346 ARG B NE 1 ATOM 5706 C CZ . ARG B 1 348 ? 182.108 40.718 -1.035 1.00 62.45 ? 346 ARG B CZ 1 ATOM 5707 N NH1 . ARG B 1 348 ? 182.013 40.432 -2.329 1.00 59.12 ? 346 ARG B NH1 1 ATOM 5708 N NH2 . ARG B 1 348 ? 182.049 39.730 -0.147 1.00 30.29 ? 346 ARG B NH2 1 ATOM 5709 N N . GLU B 1 349 ? 186.400 46.734 1.651 1.00 23.54 ? 347 GLU B N 1 ATOM 5710 C CA . GLU B 1 349 ? 187.181 47.895 1.221 1.00 22.56 ? 347 GLU B CA 1 ATOM 5711 C C . GLU B 1 349 ? 188.678 47.652 1.450 1.00 26.46 ? 347 GLU B C 1 ATOM 5712 O O . GLU B 1 349 ? 189.486 48.011 0.591 1.00 24.82 ? 347 GLU B O 1 ATOM 5713 C CB . GLU B 1 349 ? 186.740 49.153 1.962 1.00 24.18 ? 347 GLU B CB 1 ATOM 5714 C CG . GLU B 1 349 ? 187.320 50.421 1.367 1.00 36.17 ? 347 GLU B CG 1 ATOM 5715 C CD . GLU B 1 349 ? 187.068 51.709 2.120 1.00 52.86 ? 347 GLU B CD 1 ATOM 5716 O OE1 . GLU B 1 349 ? 187.717 52.721 1.765 1.00 59.59 ? 347 GLU B OE1 1 ATOM 5717 O OE2 . GLU B 1 349 ? 186.242 51.711 3.064 1.00 33.13 ? 347 GLU B OE2 1 ATOM 5718 N N . PHE B 1 350 ? 189.055 47.029 2.603 1.00 23.56 ? 348 PHE B N 1 ATOM 5719 C CA . PHE B 1 350 ? 190.471 46.713 2.875 1.00 22.07 ? 348 PHE B CA 1 ATOM 5720 C C . PHE B 1 350 ? 191.019 45.736 1.827 1.00 28.04 ? 348 PHE B C 1 ATOM 5721 O O . PHE B 1 350 ? 192.145 45.915 1.380 1.00 26.10 ? 348 PHE B O 1 ATOM 5722 C CB . PHE B 1 350 ? 190.674 46.168 4.311 1.00 22.20 ? 348 PHE B CB 1 ATOM 5723 C CG . PHE B 1 350 ? 191.905 45.308 4.540 1.00 21.77 ? 348 PHE B CG 1 ATOM 5724 C CD1 . PHE B 1 350 ? 193.185 45.878 4.577 1.00 22.56 ? 348 PHE B CD1 1 ATOM 5725 C CD2 . PHE B 1 350 ? 191.791 43.926 4.697 1.00 20.14 ? 348 PHE B CD2 1 ATOM 5726 C CE1 . PHE B 1 350 ? 194.325 45.075 4.730 1.00 20.73 ? 348 PHE B CE1 1 ATOM 5727 C CE2 . PHE B 1 350 ? 192.929 43.131 4.880 1.00 21.05 ? 348 PHE B CE2 1 ATOM 5728 C CZ . PHE B 1 350 ? 194.182 43.712 4.903 1.00 18.57 ? 348 PHE B CZ 1 ATOM 5729 N N . TRP B 1 351 ? 190.223 44.703 1.454 1.00 28.09 ? 349 TRP B N 1 ATOM 5730 C CA . TRP B 1 351 ? 190.646 43.669 0.496 1.00 29.29 ? 349 TRP B CA 1 ATOM 5731 C C . TRP B 1 351 ? 190.993 44.260 -0.865 1.00 29.57 ? 349 TRP B C 1 ATOM 5732 O O . TRP B 1 351 ? 192.074 44.016 -1.367 1.00 29.60 ? 349 TRP B O 1 ATOM 5733 C CB . TRP B 1 351 ? 189.579 42.583 0.349 1.00 29.62 ? 349 TRP B CB 1 ATOM 5734 C CG . TRP B 1 351 ? 190.119 41.277 -0.147 1.00 32.23 ? 349 TRP B CG 1 ATOM 5735 C CD1 . TRP B 1 351 ? 190.065 40.794 -1.422 1.00 35.18 ? 349 TRP B CD1 1 ATOM 5736 C CD2 . TRP B 1 351 ? 190.702 40.232 0.652 1.00 32.71 ? 349 TRP B CD2 1 ATOM 5737 N NE1 . TRP B 1 351 ? 190.621 39.535 -1.478 1.00 34.33 ? 349 TRP B NE1 1 ATOM 5738 C CE2 . TRP B 1 351 ? 190.990 39.152 -0.215 1.00 36.54 ? 349 TRP B CE2 1 ATOM 5739 C CE3 . TRP B 1 351 ? 190.962 40.083 2.028 1.00 33.52 ? 349 TRP B CE3 1 ATOM 5740 C CZ2 . TRP B 1 351 ? 191.613 37.977 0.237 1.00 36.20 ? 349 TRP B CZ2 1 ATOM 5741 C CZ3 . TRP B 1 351 ? 191.553 38.907 2.473 1.00 34.43 ? 349 TRP B CZ3 1 ATOM 5742 C CH2 . TRP B 1 351 ? 191.906 37.888 1.583 1.00 34.90 ? 349 TRP B CH2 1 ATOM 5743 N N . GLU B 1 352 ? 190.091 45.076 -1.430 1.00 24.04 ? 350 GLU B N 1 ATOM 5744 C CA . GLU B 1 352 ? 190.244 45.737 -2.715 1.00 22.45 ? 350 GLU B CA 1 ATOM 5745 C C . GLU B 1 352 ? 191.509 46.600 -2.745 1.00 28.04 ? 350 GLU B C 1 ATOM 5746 O O . GLU B 1 352 ? 192.212 46.624 -3.763 1.00 28.29 ? 350 GLU B O 1 ATOM 5747 C CB . GLU B 1 352 ? 189.017 46.577 -3.015 1.00 23.01 ? 350 GLU B CB 1 ATOM 5748 C CG . GLU B 1 352 ? 187.773 45.770 -3.314 1.00 32.96 ? 350 GLU B CG 1 ATOM 5749 C CD . GLU B 1 352 ? 186.677 46.509 -4.070 1.00 60.37 ? 350 GLU B CD 1 ATOM 5750 O OE1 . GLU B 1 352 ? 185.753 45.834 -4.579 1.00 61.69 ? 350 GLU B OE1 1 ATOM 5751 O OE2 . GLU B 1 352 ? 186.744 47.757 -4.167 1.00 47.63 ? 350 GLU B OE2 1 ATOM 5752 N N . GLN B 1 353 ? 191.814 47.287 -1.620 1.00 24.18 ? 351 GLN B N 1 ATOM 5753 C CA . GLN B 1 353 ? 193.026 48.095 -1.502 1.00 23.16 ? 351 GLN B CA 1 ATOM 5754 C C . GLN B 1 353 ? 194.255 47.208 -1.423 1.00 27.10 ? 351 GLN B C 1 ATOM 5755 O O . GLN B 1 353 ? 195.141 47.309 -2.270 1.00 27.39 ? 351 GLN B O 1 ATOM 5756 C CB . GLN B 1 353 ? 192.959 49.087 -0.331 1.00 23.49 ? 351 GLN B CB 1 ATOM 5757 C CG . GLN B 1 353 ? 194.226 49.913 -0.228 1.00 30.21 ? 351 GLN B CG 1 ATOM 5758 C CD . GLN B 1 353 ? 194.163 50.923 0.887 1.00 51.89 ? 351 GLN B CD 1 ATOM 5759 O OE1 . GLN B 1 353 ? 193.246 51.762 0.954 1.00 50.26 ? 351 GLN B OE1 1 ATOM 5760 N NE2 . GLN B 1 353 ? 195.176 50.900 1.749 1.00 28.77 ? 351 GLN B NE2 1 ATOM 5761 N N . ARG B 1 354 ? 194.296 46.333 -0.423 1.00 24.08 ? 352 ARG B N 1 ATOM 5762 C CA . ARG B 1 354 ? 195.410 45.422 -0.191 1.00 24.56 ? 352 ARG B CA 1 ATOM 5763 C C . ARG B 1 354 ? 195.787 44.593 -1.439 1.00 30.66 ? 352 ARG B C 1 ATOM 5764 O O . ARG B 1 354 ? 196.982 44.467 -1.752 1.00 30.88 ? 352 ARG B O 1 ATOM 5765 C CB . ARG B 1 354 ? 195.103 44.509 1.026 1.00 21.44 ? 352 ARG B CB 1 ATOM 5766 C CG . ARG B 1 354 ? 196.128 43.409 1.281 1.00 20.52 ? 352 ARG B CG 1 ATOM 5767 C CD . ARG B 1 354 ? 197.550 43.947 1.393 1.00 25.47 ? 352 ARG B CD 1 ATOM 5768 N NE . ARG B 1 354 ? 198.534 42.876 1.519 1.00 44.32 ? 352 ARG B NE 1 ATOM 5769 C CZ . ARG B 1 354 ? 199.107 42.245 0.495 1.00 63.77 ? 352 ARG B CZ 1 ATOM 5770 N NH1 . ARG B 1 354 ? 199.994 41.288 0.715 1.00 35.23 ? 352 ARG B NH1 1 ATOM 5771 N NH2 . ARG B 1 354 ? 198.789 42.564 -0.757 1.00 62.75 ? 352 ARG B NH2 1 ATOM 5772 N N . PHE B 1 355 ? 194.776 44.031 -2.130 1.00 26.80 ? 353 PHE B N 1 ATOM 5773 C CA . PHE B 1 355 ? 194.995 43.142 -3.274 1.00 27.06 ? 353 PHE B CA 1 ATOM 5774 C C . PHE B 1 355 ? 194.743 43.790 -4.637 1.00 33.37 ? 353 PHE B C 1 ATOM 5775 O O . PHE B 1 355 ? 194.775 43.111 -5.660 1.00 32.54 ? 353 PHE B O 1 ATOM 5776 C CB . PHE B 1 355 ? 194.189 41.839 -3.092 1.00 27.62 ? 353 PHE B CB 1 ATOM 5777 C CG . PHE B 1 355 ? 194.760 41.013 -1.953 1.00 28.48 ? 353 PHE B CG 1 ATOM 5778 C CD1 . PHE B 1 355 ? 196.076 40.561 -1.987 1.00 29.82 ? 353 PHE B CD1 1 ATOM 5779 C CD2 . PHE B 1 355 ? 193.991 40.710 -0.837 1.00 31.13 ? 353 PHE B CD2 1 ATOM 5780 C CE1 . PHE B 1 355 ? 196.602 39.796 -0.944 1.00 30.57 ? 353 PHE B CE1 1 ATOM 5781 C CE2 . PHE B 1 355 ? 194.524 39.952 0.214 1.00 33.04 ? 353 PHE B CE2 1 ATOM 5782 C CZ . PHE B 1 355 ? 195.817 39.471 0.136 1.00 30.01 ? 353 PHE B CZ 1 ATOM 5783 N N . ARG B 1 356 ? 194.547 45.109 -4.648 1.00 32.51 ? 354 ARG B N 1 ATOM 5784 C CA . ARG B 1 356 ? 194.314 45.936 -5.836 1.00 33.24 ? 354 ARG B CA 1 ATOM 5785 C C . ARG B 1 356 ? 193.378 45.238 -6.813 1.00 38.45 ? 354 ARG B C 1 ATOM 5786 O O . ARG B 1 356 ? 193.624 45.147 -8.010 1.00 40.42 ? 354 ARG B O 1 ATOM 5787 C CB . ARG B 1 356 ? 195.641 46.425 -6.449 1.00 34.73 ? 354 ARG B CB 1 ATOM 5788 C CG . ARG B 1 356 ? 196.169 47.605 -5.620 1.00 45.29 ? 354 ARG B CG 1 ATOM 5789 C CD . ARG B 1 356 ? 197.454 48.219 -6.087 1.00 50.21 ? 354 ARG B CD 1 ATOM 5790 N NE . ARG B 1 356 ? 197.300 49.666 -6.226 1.00 63.07 ? 354 ARG B NE 1 ATOM 5791 C CZ . ARG B 1 356 ? 197.048 50.279 -7.376 1.00 84.62 ? 354 ARG B CZ 1 ATOM 5792 N NH1 . ARG B 1 356 ? 196.908 51.596 -7.415 1.00 70.52 ? 354 ARG B NH1 1 ATOM 5793 N NH2 . ARG B 1 356 ? 196.946 49.580 -8.500 1.00 85.43 ? 354 ARG B NH2 1 ATOM 5794 N N . CYS B 1 357 ? 192.278 44.765 -6.265 1.00 34.00 ? 355 CYS B N 1 ATOM 5795 C CA . CYS B 1 357 ? 191.263 44.033 -6.983 1.00 33.64 ? 355 CYS B CA 1 ATOM 5796 C C . CYS B 1 357 ? 189.938 44.767 -6.792 1.00 35.36 ? 355 CYS B C 1 ATOM 5797 O O . CYS B 1 357 ? 189.933 45.865 -6.225 1.00 35.31 ? 355 CYS B O 1 ATOM 5798 C CB . CYS B 1 357 ? 191.220 42.573 -6.501 1.00 34.72 ? 355 CYS B CB 1 ATOM 5799 S SG . CYS B 1 357 ? 190.762 42.344 -4.756 1.00 39.03 ? 355 CYS B SG 1 ATOM 5800 N N . SER B 1 358 ? 188.832 44.182 -7.281 1.00 30.31 ? 356 SER B N 1 ATOM 5801 C CA . SER B 1 358 ? 187.488 44.740 -7.254 1.00 29.82 ? 356 SER B CA 1 ATOM 5802 C C . SER B 1 358 ? 186.488 43.593 -7.274 1.00 34.03 ? 356 SER B C 1 ATOM 5803 O O . SER B 1 358 ? 186.539 42.767 -8.180 1.00 33.11 ? 356 SER B O 1 ATOM 5804 C CB . SER B 1 358 ? 187.284 45.652 -8.469 1.00 33.71 ? 356 SER B CB 1 ATOM 5805 O OG . SER B 1 358 ? 186.009 45.567 -9.089 1.00 41.79 ? 356 SER B OG 1 ATOM 5806 N N . PHE B 1 359 ? 185.563 43.560 -6.298 1.00 31.19 ? 357 PHE B N 1 ATOM 5807 C CA . PHE B 1 359 ? 184.518 42.542 -6.215 1.00 30.89 ? 357 PHE B CA 1 ATOM 5808 C C . PHE B 1 359 ? 183.542 42.611 -7.388 1.00 36.46 ? 357 PHE B C 1 ATOM 5809 O O . PHE B 1 359 ? 183.058 41.572 -7.821 1.00 36.96 ? 357 PHE B O 1 ATOM 5810 C CB . PHE B 1 359 ? 183.796 42.575 -4.861 1.00 32.53 ? 357 PHE B CB 1 ATOM 5811 C CG . PHE B 1 359 ? 184.694 42.184 -3.705 1.00 34.01 ? 357 PHE B CG 1 ATOM 5812 C CD1 . PHE B 1 359 ? 184.940 40.847 -3.414 1.00 34.70 ? 357 PHE B CD1 1 ATOM 5813 C CD2 . PHE B 1 359 ? 185.315 43.156 -2.926 1.00 36.30 ? 357 PHE B CD2 1 ATOM 5814 C CE1 . PHE B 1 359 ? 185.789 40.493 -2.376 1.00 35.50 ? 357 PHE B CE1 1 ATOM 5815 C CE2 . PHE B 1 359 ? 186.168 42.798 -1.885 1.00 38.97 ? 357 PHE B CE2 1 ATOM 5816 C CZ . PHE B 1 359 ? 186.426 41.469 -1.642 1.00 36.78 ? 357 PHE B CZ 1 ATOM 5817 N N . ARG B 1 360 ? 183.314 43.808 -7.948 1.00 34.19 ? 358 ARG B N 1 ATOM 5818 C CA . ARG B 1 360 ? 182.475 43.990 -9.139 1.00 34.97 ? 358 ARG B CA 1 ATOM 5819 C C . ARG B 1 360 ? 183.099 43.245 -10.329 1.00 39.36 ? 358 ARG B C 1 ATOM 5820 O O . ARG B 1 360 ? 182.400 42.566 -11.075 1.00 39.00 ? 358 ARG B O 1 ATOM 5821 C CB . ARG B 1 360 ? 182.327 45.490 -9.458 1.00 34.04 ? 358 ARG B CB 1 ATOM 5822 C CG . ARG B 1 360 ? 181.397 45.819 -10.624 1.00 29.98 ? 358 ARG B CG 1 ATOM 5823 C CD . ARG B 1 360 ? 181.356 47.324 -10.834 1.00 33.44 ? 358 ARG B CD 1 ATOM 5824 N NE . ARG B 1 360 ? 180.499 48.011 -9.868 1.00 32.40 ? 358 ARG B NE 1 ATOM 5825 C CZ . ARG B 1 360 ? 180.364 49.331 -9.798 1.00 56.56 ? 358 ARG B CZ 1 ATOM 5826 N NH1 . ARG B 1 360 ? 179.543 49.874 -8.905 1.00 49.58 ? 358 ARG B NH1 1 ATOM 5827 N NH2 . ARG B 1 360 ? 181.059 50.122 -10.611 1.00 48.39 ? 358 ARG B NH2 1 ATOM 5828 N N . GLN B 1 361 ? 184.432 43.318 -10.431 1.00 37.64 ? 359 GLN B N 1 ATOM 5829 C CA . GLN B 1 361 ? 185.250 42.693 -11.476 1.00 38.08 ? 359 GLN B CA 1 ATOM 5830 C C . GLN B 1 361 ? 185.498 41.230 -11.242 1.00 41.34 ? 359 GLN B C 1 ATOM 5831 O O . GLN B 1 361 ? 186.280 40.640 -11.983 1.00 41.83 ? 359 GLN B O 1 ATOM 5832 C CB . GLN B 1 361 ? 186.621 43.391 -11.606 1.00 39.53 ? 359 GLN B CB 1 ATOM 5833 C CG . GLN B 1 361 ? 186.574 44.795 -12.138 1.00 55.62 ? 359 GLN B CG 1 ATOM 5834 C CD . GLN B 1 361 ? 186.317 44.865 -13.600 1.00 72.50 ? 359 GLN B CD 1 ATOM 5835 O OE1 . GLN B 1 361 ? 185.410 44.205 -14.122 1.00 65.96 ? 359 GLN B OE1 1 ATOM 5836 N NE2 . GLN B 1 361 ? 187.031 45.777 -14.255 1.00 70.50 ? 359 GLN B NE2 1 ATOM 5837 N N . ARG B 1 362 ? 184.924 40.659 -10.185 1.00 37.42 ? 360 ARG B N 1 ATOM 5838 C CA . ARG B 1 362 ? 185.105 39.252 -9.853 1.00 37.53 ? 360 ARG B CA 1 ATOM 5839 C C . ARG B 1 362 ? 186.585 38.793 -9.924 1.00 40.89 ? 360 ARG B C 1 ATOM 5840 O O . ARG B 1 362 ? 186.860 37.724 -10.458 1.00 40.85 ? 360 ARG B O 1 ATOM 5841 C CB . ARG B 1 362 ? 184.181 38.370 -10.736 1.00 37.95 ? 360 ARG B CB 1 ATOM 5842 C CG . ARG B 1 362 ? 182.695 38.725 -10.652 1.00 48.90 ? 360 ARG B CG 1 ATOM 5843 C CD . ARG B 1 362 ? 181.964 38.113 -11.822 1.00 66.43 ? 360 ARG B CD 1 ATOM 5844 N NE . ARG B 1 362 ? 180.512 38.089 -11.641 1.00 79.63 ? 360 ARG B NE 1 ATOM 5845 C CZ . ARG B 1 362 ? 179.684 37.375 -12.398 1.00 97.05 ? 360 ARG B CZ 1 ATOM 5846 N NH1 . ARG B 1 362 ? 180.158 36.610 -13.377 1.00 83.21 ? 360 ARG B NH1 1 ATOM 5847 N NH2 . ARG B 1 362 ? 178.376 37.412 -12.176 1.00 87.39 ? 360 ARG B NH2 1 ATOM 5848 N N . ASP B 1 363 ? 187.527 39.609 -9.423 1.00 37.56 ? 361 ASP B N 1 ATOM 5849 C CA . ASP B 1 363 ? 188.964 39.280 -9.435 1.00 38.61 ? 361 ASP B CA 1 ATOM 5850 C C . ASP B 1 363 ? 189.632 39.357 -8.053 1.00 43.06 ? 361 ASP B C 1 ATOM 5851 O O . ASP B 1 363 ? 190.869 39.531 -7.970 1.00 42.65 ? 361 ASP B O 1 ATOM 5852 C CB . ASP B 1 363 ? 189.717 40.186 -10.420 1.00 41.70 ? 361 ASP B CB 1 ATOM 5853 C CG . ASP B 1 363 ? 189.553 41.694 -10.228 1.00 54.72 ? 361 ASP B CG 1 ATOM 5854 O OD1 . ASP B 1 363 ? 189.161 42.121 -9.118 1.00 51.34 ? 361 ASP B OD1 1 ATOM 5855 O OD2 . ASP B 1 363 ? 189.833 42.445 -11.188 1.00 67.04 ? 361 ASP B OD2 1 ATOM 5856 N N . CYS B 1 364 ? 188.802 39.254 -6.973 1.00 38.34 ? 362 CYS B N 1 ATOM 5857 C CA . CYS B 1 364 ? 189.261 39.353 -5.590 1.00 37.60 ? 362 CYS B CA 1 ATOM 5858 C C . CYS B 1 364 ? 189.471 38.008 -4.908 1.00 43.35 ? 362 CYS B C 1 ATOM 5859 O O . CYS B 1 364 ? 190.385 37.911 -4.077 1.00 42.01 ? 362 CYS B O 1 ATOM 5860 C CB . CYS B 1 364 ? 188.351 40.257 -4.765 1.00 36.47 ? 362 CYS B CB 1 ATOM 5861 S SG . CYS B 1 364 ? 188.728 42.021 -4.910 1.00 39.81 ? 362 CYS B SG 1 ATOM 5862 N N . ALA B 1 365 ? 188.649 36.977 -5.255 1.00 42.24 ? 363 ALA B N 1 ATOM 5863 C CA . ALA B 1 365 ? 188.709 35.623 -4.657 1.00 43.02 ? 363 ALA B CA 1 ATOM 5864 C C . ALA B 1 365 ? 190.048 34.910 -4.821 1.00 48.65 ? 363 ALA B C 1 ATOM 5865 O O . ALA B 1 365 ? 190.440 34.114 -3.962 1.00 48.37 ? 363 ALA B O 1 ATOM 5866 C CB . ALA B 1 365 ? 187.589 34.759 -5.184 1.00 43.52 ? 363 ALA B CB 1 ATOM 5867 N N . ALA B 1 366 ? 190.759 35.252 -5.906 1.00 45.74 ? 364 ALA B N 1 ATOM 5868 C CA . ALA B 1 366 ? 192.079 34.768 -6.293 1.00 45.51 ? 364 ALA B CA 1 ATOM 5869 C C . ALA B 1 366 ? 193.132 34.882 -5.180 1.00 46.47 ? 364 ALA B C 1 ATOM 5870 O O . ALA B 1 366 ? 194.062 34.072 -5.145 1.00 47.79 ? 364 ALA B O 1 ATOM 5871 C CB . ALA B 1 366 ? 192.543 35.554 -7.509 1.00 46.70 ? 364 ALA B CB 1 ATOM 5872 N N . HIS B 1 367 ? 192.985 35.886 -4.284 1.00 37.69 ? 365 HIS B N 1 ATOM 5873 C CA . HIS B 1 367 ? 193.931 36.215 -3.204 1.00 34.60 ? 365 HIS B CA 1 ATOM 5874 C C . HIS B 1 367 ? 193.587 35.637 -1.801 1.00 36.14 ? 365 HIS B C 1 ATOM 5875 O O . HIS B 1 367 ? 192.427 35.321 -1.489 1.00 32.46 ? 365 HIS B O 1 ATOM 5876 C CB . HIS B 1 367 ? 194.084 37.742 -3.099 1.00 33.64 ? 365 HIS B CB 1 ATOM 5877 C CG . HIS B 1 367 ? 194.297 38.456 -4.398 1.00 35.53 ? 365 HIS B CG 1 ATOM 5878 N ND1 . HIS B 1 367 ? 195.570 38.853 -4.813 1.00 35.90 ? 365 HIS B ND1 1 ATOM 5879 C CD2 . HIS B 1 367 ? 193.389 38.870 -5.314 1.00 35.86 ? 365 HIS B CD2 1 ATOM 5880 C CE1 . HIS B 1 367 ? 195.389 39.487 -5.954 1.00 34.40 ? 365 HIS B CE1 1 ATOM 5881 N NE2 . HIS B 1 367 ? 194.096 39.510 -6.304 1.00 35.08 ? 365 HIS B NE2 1 ATOM 5882 N N . SER B 1 368 ? 194.620 35.585 -0.941 1.00 34.57 ? 366 SER B N 1 ATOM 5883 C CA . SER B 1 368 ? 194.556 35.081 0.435 1.00 35.44 ? 366 SER B CA 1 ATOM 5884 C C . SER B 1 368 ? 195.498 35.834 1.375 1.00 41.89 ? 366 SER B C 1 ATOM 5885 O O . SER B 1 368 ? 196.571 36.307 0.961 1.00 41.94 ? 366 SER B O 1 ATOM 5886 C CB . SER B 1 368 ? 194.908 33.593 0.474 1.00 38.47 ? 366 SER B CB 1 ATOM 5887 O OG . SER B 1 368 ? 194.791 33.040 1.775 1.00 47.76 ? 366 SER B OG 1 ATOM 5888 N N . LEU B 1 369 ? 195.101 35.903 2.663 1.00 38.51 ? 367 LEU B N 1 ATOM 5889 C CA . LEU B 1 369 ? 195.912 36.497 3.716 1.00 37.78 ? 367 LEU B CA 1 ATOM 5890 C C . LEU B 1 369 ? 196.900 35.452 4.236 1.00 45.80 ? 367 LEU B C 1 ATOM 5891 O O . LEU B 1 369 ? 197.897 35.801 4.876 1.00 44.77 ? 367 LEU B O 1 ATOM 5892 C CB . LEU B 1 369 ? 195.036 37.100 4.833 1.00 36.67 ? 367 LEU B CB 1 ATOM 5893 C CG . LEU B 1 369 ? 194.492 38.523 4.522 1.00 39.43 ? 367 LEU B CG 1 ATOM 5894 C CD1 . LEU B 1 369 ? 193.566 39.031 5.606 1.00 38.62 ? 367 LEU B CD1 1 ATOM 5895 C CD2 . LEU B 1 369 ? 195.607 39.531 4.266 1.00 39.32 ? 367 LEU B CD2 1 ATOM 5896 N N . ARG B 1 370 ? 196.641 34.164 3.884 1.00 46.38 ? 368 ARG B N 1 ATOM 5897 C CA . ARG B 1 370 ? 197.443 32.982 4.224 1.00 47.41 ? 368 ARG B CA 1 ATOM 5898 C C . ARG B 1 370 ? 198.613 32.808 3.250 1.00 53.55 ? 368 ARG B C 1 ATOM 5899 O O . ARG B 1 370 ? 199.664 32.303 3.653 1.00 53.67 ? 368 ARG B O 1 ATOM 5900 C CB . ARG B 1 370 ? 196.564 31.722 4.229 1.00 47.72 ? 368 ARG B CB 1 ATOM 5901 C CG . ARG B 1 370 ? 196.301 31.183 5.622 1.00 58.76 ? 368 ARG B CG 1 ATOM 5902 C CD . ARG B 1 370 ? 194.910 30.598 5.738 1.00 72.68 ? 368 ARG B CD 1 ATOM 5903 N NE . ARG B 1 370 ? 194.618 30.192 7.115 1.00 87.75 ? 368 ARG B NE 1 ATOM 5904 C CZ . ARG B 1 370 ? 193.414 29.844 7.564 1.00 106.33 ? 368 ARG B CZ 1 ATOM 5905 N NH1 . ARG B 1 370 ? 192.362 29.855 6.750 1.00 88.32 ? 368 ARG B NH1 1 ATOM 5906 N NH2 . ARG B 1 370 ? 193.249 29.492 8.833 1.00 99.75 ? 368 ARG B NH2 1 ATOM 5907 N N . ALA B 1 371 ? 198.431 33.239 1.977 1.00 51.20 ? 369 ALA B N 1 ATOM 5908 C CA . ALA B 1 371 ? 199.435 33.152 0.907 1.00 51.56 ? 369 ALA B CA 1 ATOM 5909 C C . ALA B 1 371 ? 200.407 34.335 0.884 1.00 56.78 ? 369 ALA B C 1 ATOM 5910 O O . ALA B 1 371 ? 201.388 34.303 0.129 1.00 57.44 ? 369 ALA B O 1 ATOM 5911 C CB . ALA B 1 371 ? 198.749 33.018 -0.443 1.00 52.45 ? 369 ALA B CB 1 ATOM 5912 N N . VAL B 1 372 ? 200.127 35.384 1.689 1.00 52.72 ? 370 VAL B N 1 ATOM 5913 C CA . VAL B 1 372 ? 200.953 36.595 1.792 1.00 51.45 ? 370 VAL B CA 1 ATOM 5914 C C . VAL B 1 372 ? 201.679 36.630 3.164 1.00 54.42 ? 370 VAL B C 1 ATOM 5915 O O . VAL B 1 372 ? 201.218 35.951 4.091 1.00 53.81 ? 370 VAL B O 1 ATOM 5916 C CB . VAL B 1 372 ? 200.109 37.864 1.528 1.00 54.12 ? 370 VAL B CB 1 ATOM 5917 N N . PRO B 1 373 ? 202.810 37.380 3.322 1.00 50.39 ? 371 PRO B N 1 ATOM 5918 C CA . PRO B 1 373 ? 203.507 37.406 4.632 1.00 49.72 ? 371 PRO B CA 1 ATOM 5919 C C . PRO B 1 373 ? 202.710 38.096 5.743 1.00 50.79 ? 371 PRO B C 1 ATOM 5920 O O . PRO B 1 373 ? 201.868 38.935 5.419 1.00 51.28 ? 371 PRO B O 1 ATOM 5921 C CB . PRO B 1 373 ? 204.811 38.167 4.329 1.00 51.48 ? 371 PRO B CB 1 ATOM 5922 C CG . PRO B 1 373 ? 204.935 38.172 2.822 1.00 55.40 ? 371 PRO B CG 1 ATOM 5923 C CD . PRO B 1 373 ? 203.525 38.220 2.334 1.00 51.15 ? 371 PRO B CD 1 ATOM 5924 N N . PHE B 1 374 ? 202.944 37.735 7.041 1.00 43.94 ? 372 PHE B N 1 ATOM 5925 C CA . PHE B 1 374 ? 202.207 38.349 8.160 1.00 41.88 ? 372 PHE B CA 1 ATOM 5926 C C . PHE B 1 374 ? 203.089 38.926 9.262 1.00 44.62 ? 372 PHE B C 1 ATOM 5927 O O . PHE B 1 374 ? 203.647 38.192 10.085 1.00 43.48 ? 372 PHE B O 1 ATOM 5928 C CB . PHE B 1 374 ? 201.134 37.419 8.782 1.00 42.51 ? 372 PHE B CB 1 ATOM 5929 C CG . PHE B 1 374 ? 200.329 38.067 9.904 1.00 42.70 ? 372 PHE B CG 1 ATOM 5930 C CD1 . PHE B 1 374 ? 199.258 38.915 9.621 1.00 44.41 ? 372 PHE B CD1 1 ATOM 5931 C CD2 . PHE B 1 374 ? 200.641 37.828 11.240 1.00 43.57 ? 372 PHE B CD2 1 ATOM 5932 C CE1 . PHE B 1 374 ? 198.520 39.511 10.656 1.00 44.51 ? 372 PHE B CE1 1 ATOM 5933 C CE2 . PHE B 1 374 ? 199.933 38.468 12.269 1.00 45.53 ? 372 PHE B CE2 1 ATOM 5934 C CZ . PHE B 1 374 ? 198.861 39.280 11.970 1.00 43.15 ? 372 PHE B CZ 1 ATOM 5935 N N . GLU B 1 375 ? 203.129 40.264 9.319 1.00 41.22 ? 373 GLU B N 1 ATOM 5936 C CA . GLU B 1 375 ? 203.812 41.012 10.371 1.00 40.13 ? 373 GLU B CA 1 ATOM 5937 C C . GLU B 1 375 ? 202.693 41.559 11.266 1.00 39.91 ? 373 GLU B C 1 ATOM 5938 O O . GLU B 1 375 ? 201.772 42.192 10.765 1.00 39.10 ? 373 GLU B O 1 ATOM 5939 C CB . GLU B 1 375 ? 204.710 42.120 9.790 1.00 41.28 ? 373 GLU B CB 1 ATOM 5940 N N . GLN B 1 376 ? 202.747 41.239 12.537 1.00 35.17 ? 374 GLN B N 1 ATOM 5941 C CA . GLN B 1 376 ? 201.757 41.648 13.494 1.00 35.09 ? 374 GLN B CA 1 ATOM 5942 C C . GLN B 1 376 ? 202.033 43.068 13.837 1.00 41.37 ? 374 GLN B C 1 ATOM 5943 O O . GLN B 1 376 ? 203.154 43.457 13.929 1.00 41.83 ? 374 GLN B O 1 ATOM 5944 C CB . GLN B 1 376 ? 201.862 40.801 14.749 1.00 35.74 ? 374 GLN B CB 1 ATOM 5945 C CG . GLN B 1 376 ? 200.688 40.883 15.692 1.00 41.46 ? 374 GLN B CG 1 ATOM 5946 C CD . GLN B 1 376 ? 200.803 39.951 16.872 1.00 65.22 ? 374 GLN B CD 1 ATOM 5947 O OE1 . GLN B 1 376 ? 200.725 38.751 16.725 1.00 57.37 ? 374 GLN B OE1 1 ATOM 5948 N NE2 . GLN B 1 376 ? 200.975 40.500 18.045 1.00 62.42 ? 374 GLN B NE2 1 ATOM 5949 N N . GLU B 1 377 ? 200.997 43.858 14.010 1.00 38.11 ? 375 GLU B N 1 ATOM 5950 C CA . GLU B 1 377 ? 201.191 45.261 14.346 1.00 36.77 ? 375 GLU B CA 1 ATOM 5951 C C . GLU B 1 377 ? 201.685 45.326 15.799 1.00 37.19 ? 375 GLU B C 1 ATOM 5952 O O . GLU B 1 377 ? 201.161 44.640 16.675 1.00 35.81 ? 375 GLU B O 1 ATOM 5953 C CB . GLU B 1 377 ? 199.910 46.078 14.067 1.00 37.72 ? 375 GLU B CB 1 ATOM 5954 C CG . GLU B 1 377 ? 200.164 47.566 13.903 1.00 42.81 ? 375 GLU B CG 1 ATOM 5955 C CD . GLU B 1 377 ? 200.461 48.320 15.191 1.00 55.21 ? 375 GLU B CD 1 ATOM 5956 O OE1 . GLU B 1 377 ? 199.709 48.131 16.179 1.00 33.12 ? 375 GLU B OE1 1 ATOM 5957 O OE2 . GLU B 1 377 ? 201.463 49.076 15.218 1.00 42.22 ? 375 GLU B OE2 1 ATOM 5958 N N . SER B 1 378 ? 202.746 46.088 16.028 1.00 33.05 ? 376 SER B N 1 ATOM 5959 C CA . SER B 1 378 ? 203.380 46.183 17.333 1.00 32.52 ? 376 SER B CA 1 ATOM 5960 C C . SER B 1 378 ? 202.446 46.437 18.543 1.00 35.90 ? 376 SER B C 1 ATOM 5961 O O . SER B 1 378 ? 202.768 45.964 19.625 1.00 36.03 ? 376 SER B O 1 ATOM 5962 C CB . SER B 1 378 ? 204.482 47.225 17.312 1.00 36.56 ? 376 SER B CB 1 ATOM 5963 O OG . SER B 1 378 ? 204.671 47.678 18.645 1.00 52.69 ? 376 SER B OG 1 ATOM 5964 N N . LYS B 1 379 ? 201.341 47.186 18.399 1.00 31.66 ? 377 LYS B N 1 ATOM 5965 C CA . LYS B 1 379 ? 200.489 47.470 19.568 1.00 30.07 ? 377 LYS B CA 1 ATOM 5966 C C . LYS B 1 379 ? 199.222 46.583 19.677 1.00 33.85 ? 377 LYS B C 1 ATOM 5967 O O . LYS B 1 379 ? 198.275 46.967 20.377 1.00 32.94 ? 377 LYS B O 1 ATOM 5968 C CB . LYS B 1 379 ? 200.123 48.957 19.635 1.00 30.75 ? 377 LYS B CB 1 ATOM 5969 C CG . LYS B 1 379 ? 201.309 49.901 19.735 1.00 31.02 ? 377 LYS B CG 1 ATOM 5970 C CD . LYS B 1 379 ? 200.827 51.265 20.189 1.00 35.92 ? 377 LYS B CD 1 ATOM 5971 C CE . LYS B 1 379 ? 201.908 52.264 20.496 1.00 33.01 ? 377 LYS B CE 1 ATOM 5972 N NZ . LYS B 1 379 ? 202.515 52.810 19.266 1.00 35.43 ? 377 LYS B NZ 1 ATOM 5973 N N . ILE B 1 380 ? 199.222 45.375 19.036 1.00 29.57 ? 378 ILE B N 1 ATOM 5974 C CA . ILE B 1 380 ? 198.075 44.449 19.095 1.00 29.18 ? 378 ILE B CA 1 ATOM 5975 C C . ILE B 1 380 ? 197.829 43.998 20.536 1.00 35.50 ? 378 ILE B C 1 ATOM 5976 O O . ILE B 1 380 ? 196.680 43.948 20.975 1.00 34.25 ? 378 ILE B O 1 ATOM 5977 C CB . ILE B 1 380 ? 198.202 43.270 18.066 1.00 31.94 ? 378 ILE B CB 1 ATOM 5978 C CG1 . ILE B 1 380 ? 198.087 43.764 16.576 1.00 32.02 ? 378 ILE B CG1 1 ATOM 5979 C CG2 . ILE B 1 380 ? 197.228 42.104 18.339 1.00 31.65 ? 378 ILE B CG2 1 ATOM 5980 C CD1 . ILE B 1 380 ? 196.907 44.631 16.180 1.00 25.30 ? 378 ILE B CD1 1 ATOM 5981 N N . MET B 1 381 ? 198.924 43.716 21.272 1.00 35.82 ? 379 MET B N 1 ATOM 5982 C CA . MET B 1 381 ? 198.937 43.306 22.677 1.00 36.90 ? 379 MET B CA 1 ATOM 5983 C C . MET B 1 381 ? 198.201 44.341 23.548 1.00 36.43 ? 379 MET B C 1 ATOM 5984 O O . MET B 1 381 ? 197.382 43.948 24.373 1.00 34.84 ? 379 MET B O 1 ATOM 5985 C CB . MET B 1 381 ? 200.377 43.116 23.149 1.00 40.69 ? 379 MET B CB 1 ATOM 5986 C CG . MET B 1 381 ? 200.458 42.508 24.500 1.00 46.79 ? 379 MET B CG 1 ATOM 5987 S SD . MET B 1 381 ? 201.986 41.598 24.749 1.00 53.65 ? 379 MET B SD 1 ATOM 5988 C CE . MET B 1 381 ? 201.495 39.927 24.176 1.00 49.62 ? 379 MET B CE 1 ATOM 5989 N N . PHE B 1 382 ? 198.424 45.647 23.297 1.00 30.04 ? 380 PHE B N 1 ATOM 5990 C CA . PHE B 1 382 ? 197.729 46.697 24.047 1.00 29.14 ? 380 PHE B CA 1 ATOM 5991 C C . PHE B 1 382 ? 196.238 46.835 23.649 1.00 31.69 ? 380 PHE B C 1 ATOM 5992 O O . PHE B 1 382 ? 195.442 47.240 24.500 1.00 32.74 ? 380 PHE B O 1 ATOM 5993 C CB . PHE B 1 382 ? 198.470 48.036 23.999 1.00 30.16 ? 380 PHE B CB 1 ATOM 5994 C CG . PHE B 1 382 ? 199.957 47.870 24.144 1.00 31.79 ? 380 PHE B CG 1 ATOM 5995 C CD1 . PHE B 1 382 ? 200.525 47.604 25.382 1.00 36.68 ? 380 PHE B CD1 1 ATOM 5996 C CD2 . PHE B 1 382 ? 200.787 47.914 23.031 1.00 33.89 ? 380 PHE B CD2 1 ATOM 5997 C CE1 . PHE B 1 382 ? 201.913 47.403 25.502 1.00 38.39 ? 380 PHE B CE1 1 ATOM 5998 C CE2 . PHE B 1 382 ? 202.173 47.734 23.152 1.00 37.23 ? 380 PHE B CE2 1 ATOM 5999 C CZ . PHE B 1 382 ? 202.728 47.465 24.379 1.00 36.15 ? 380 PHE B CZ 1 ATOM 6000 N N . VAL B 1 383 ? 195.844 46.438 22.411 1.00 25.33 ? 381 VAL B N 1 ATOM 6001 C CA . VAL B 1 383 ? 194.422 46.444 21.999 1.00 23.99 ? 381 VAL B CA 1 ATOM 6002 C C . VAL B 1 383 ? 193.687 45.356 22.815 1.00 26.30 ? 381 VAL B C 1 ATOM 6003 O O . VAL B 1 383 ? 192.757 45.657 23.563 1.00 26.25 ? 381 VAL B O 1 ATOM 6004 C CB . VAL B 1 383 ? 194.174 46.334 20.458 1.00 26.62 ? 381 VAL B CB 1 ATOM 6005 C CG1 . VAL B 1 383 ? 192.690 46.286 20.148 1.00 26.42 ? 381 VAL B CG1 1 ATOM 6006 C CG2 . VAL B 1 383 ? 194.824 47.483 19.702 1.00 25.74 ? 381 VAL B CG2 1 ATOM 6007 N N . VAL B 1 384 ? 194.198 44.132 22.755 1.00 21.90 ? 382 VAL B N 1 ATOM 6008 C CA . VAL B 1 384 ? 193.708 42.981 23.508 1.00 21.19 ? 382 VAL B CA 1 ATOM 6009 C C . VAL B 1 384 ? 193.675 43.317 25.013 1.00 24.96 ? 382 VAL B C 1 ATOM 6010 O O . VAL B 1 384 ? 192.625 43.197 25.636 1.00 26.86 ? 382 VAL B O 1 ATOM 6011 C CB . VAL B 1 384 ? 194.578 41.730 23.203 1.00 24.54 ? 382 VAL B CB 1 ATOM 6012 C CG1 . VAL B 1 384 ? 194.191 40.551 24.091 1.00 23.62 ? 382 VAL B CG1 1 ATOM 6013 C CG2 . VAL B 1 384 ? 194.508 41.346 21.708 1.00 24.32 ? 382 VAL B CG2 1 ATOM 6014 N N . ASN B 1 385 ? 194.773 43.802 25.571 1.00 20.08 ? 383 ASN B N 1 ATOM 6015 C CA . ASN B 1 385 ? 194.822 44.119 26.993 1.00 20.52 ? 383 ASN B CA 1 ATOM 6016 C C . ASN B 1 385 ? 193.803 45.163 27.398 1.00 26.83 ? 383 ASN B C 1 ATOM 6017 O O . ASN B 1 385 ? 193.200 45.016 28.462 1.00 25.86 ? 383 ASN B O 1 ATOM 6018 C CB . ASN B 1 385 ? 196.227 44.531 27.428 1.00 21.81 ? 383 ASN B CB 1 ATOM 6019 C CG . ASN B 1 385 ? 197.237 43.403 27.485 1.00 37.06 ? 383 ASN B CG 1 ATOM 6020 O OD1 . ASN B 1 385 ? 196.899 42.201 27.430 1.00 33.13 ? 383 ASN B OD1 1 ATOM 6021 N ND2 . ASN B 1 385 ? 198.505 43.773 27.638 1.00 20.45 ? 383 ASN B ND2 1 ATOM 6022 N N . ALA B 1 386 ? 193.568 46.194 26.536 1.00 25.00 ? 384 ALA B N 1 ATOM 6023 C CA . ALA B 1 386 ? 192.569 47.245 26.813 1.00 23.84 ? 384 ALA B CA 1 ATOM 6024 C C . ALA B 1 386 ? 191.178 46.619 26.921 1.00 25.61 ? 384 ALA B C 1 ATOM 6025 O O . ALA B 1 386 ? 190.442 46.921 27.861 1.00 22.98 ? 384 ALA B O 1 ATOM 6026 C CB . ALA B 1 386 ? 192.589 48.314 25.724 1.00 24.04 ? 384 ALA B CB 1 ATOM 6027 N N . VAL B 1 387 ? 190.842 45.724 25.967 1.00 22.31 ? 385 VAL B N 1 ATOM 6028 C CA . VAL B 1 387 ? 189.542 45.072 25.896 1.00 22.29 ? 385 VAL B CA 1 ATOM 6029 C C . VAL B 1 387 ? 189.321 44.220 27.130 1.00 26.74 ? 385 VAL B C 1 ATOM 6030 O O . VAL B 1 387 ? 188.273 44.328 27.762 1.00 26.54 ? 385 VAL B O 1 ATOM 6031 C CB . VAL B 1 387 ? 189.364 44.315 24.562 1.00 26.51 ? 385 VAL B CB 1 ATOM 6032 C CG1 . VAL B 1 387 ? 187.996 43.655 24.494 1.00 26.90 ? 385 VAL B CG1 1 ATOM 6033 C CG2 . VAL B 1 387 ? 189.538 45.265 23.376 1.00 26.36 ? 385 VAL B CG2 1 ATOM 6034 N N . TYR B 1 388 ? 190.351 43.439 27.513 1.00 23.37 ? 386 TYR B N 1 ATOM 6035 C CA . TYR B 1 388 ? 190.347 42.570 28.686 1.00 23.22 ? 386 TYR B CA 1 ATOM 6036 C C . TYR B 1 388 ? 190.266 43.367 29.964 1.00 27.26 ? 386 TYR B C 1 ATOM 6037 O O . TYR B 1 388 ? 189.577 42.950 30.892 1.00 27.13 ? 386 TYR B O 1 ATOM 6038 C CB . TYR B 1 388 ? 191.592 41.680 28.697 1.00 24.49 ? 386 TYR B CB 1 ATOM 6039 C CG . TYR B 1 388 ? 191.375 40.353 28.000 1.00 26.37 ? 386 TYR B CG 1 ATOM 6040 C CD1 . TYR B 1 388 ? 191.548 40.229 26.621 1.00 27.62 ? 386 TYR B CD1 1 ATOM 6041 C CD2 . TYR B 1 388 ? 190.945 39.232 28.711 1.00 27.05 ? 386 TYR B CD2 1 ATOM 6042 C CE1 . TYR B 1 388 ? 191.305 39.018 25.969 1.00 29.79 ? 386 TYR B CE1 1 ATOM 6043 C CE2 . TYR B 1 388 ? 190.713 38.013 28.074 1.00 28.00 ? 386 TYR B CE2 1 ATOM 6044 C CZ . TYR B 1 388 ? 190.908 37.905 26.705 1.00 36.71 ? 386 TYR B CZ 1 ATOM 6045 O OH . TYR B 1 388 ? 190.691 36.691 26.103 1.00 34.49 ? 386 TYR B OH 1 ATOM 6046 N N . ALA B 1 389 ? 190.967 44.526 30.017 1.00 22.06 ? 387 ALA B N 1 ATOM 6047 C CA . ALA B 1 389 ? 190.962 45.394 31.180 1.00 20.39 ? 387 ALA B CA 1 ATOM 6048 C C . ALA B 1 389 ? 189.520 45.802 31.521 1.00 24.80 ? 387 ALA B C 1 ATOM 6049 O O . ALA B 1 389 ? 189.102 45.630 32.655 1.00 25.94 ? 387 ALA B O 1 ATOM 6050 C CB . ALA B 1 389 ? 191.838 46.602 30.933 1.00 20.63 ? 387 ALA B CB 1 ATOM 6051 N N . MET B 1 390 ? 188.761 46.186 30.532 1.00 20.27 ? 388 MET B N 1 ATOM 6052 C CA . MET B 1 390 ? 187.392 46.530 30.672 1.00 19.38 ? 388 MET B CA 1 ATOM 6053 C C . MET B 1 390 ? 186.489 45.364 30.993 1.00 23.75 ? 388 MET B C 1 ATOM 6054 O O . MET B 1 390 ? 185.565 45.492 31.709 1.00 23.08 ? 388 MET B O 1 ATOM 6055 C CB . MET B 1 390 ? 186.970 47.222 29.392 1.00 21.98 ? 388 MET B CB 1 ATOM 6056 C CG . MET B 1 390 ? 185.603 47.845 29.417 1.00 27.43 ? 388 MET B CG 1 ATOM 6057 S SD . MET B 1 390 ? 185.495 49.353 30.335 1.00 33.67 ? 388 MET B SD 1 ATOM 6058 C CE . MET B 1 390 ? 186.339 50.452 29.231 1.00 30.48 ? 388 MET B CE 1 ATOM 6059 N N . ALA B 1 391 ? 186.777 44.220 30.436 1.00 20.92 ? 389 ALA B N 1 ATOM 6060 C CA . ALA B 1 391 ? 186.076 42.982 30.730 1.00 20.60 ? 389 ALA B CA 1 ATOM 6061 C C . ALA B 1 391 ? 186.281 42.580 32.184 1.00 25.25 ? 389 ALA B C 1 ATOM 6062 O O . ALA B 1 391 ? 185.286 42.339 32.865 1.00 26.37 ? 389 ALA B O 1 ATOM 6063 C CB . ALA B 1 391 ? 186.534 41.872 29.786 1.00 21.55 ? 389 ALA B CB 1 ATOM 6064 N N . HIS B 1 392 ? 187.545 42.587 32.686 1.00 21.78 ? 390 HIS B N 1 ATOM 6065 C CA . HIS B 1 392 ? 187.880 42.273 34.093 1.00 21.92 ? 390 HIS B CA 1 ATOM 6066 C C . HIS B 1 392 ? 187.203 43.255 35.049 1.00 25.53 ? 390 HIS B C 1 ATOM 6067 O O . HIS B 1 392 ? 186.578 42.821 36.000 1.00 24.70 ? 390 HIS B O 1 ATOM 6068 C CB . HIS B 1 392 ? 189.398 42.178 34.324 1.00 22.94 ? 390 HIS B CB 1 ATOM 6069 C CG . HIS B 1 392 ? 189.977 40.863 33.880 1.00 26.95 ? 390 HIS B CG 1 ATOM 6070 N ND1 . HIS B 1 392 ? 189.955 39.749 34.704 1.00 28.77 ? 390 HIS B ND1 1 ATOM 6071 C CD2 . HIS B 1 392 ? 190.503 40.503 32.685 1.00 28.97 ? 390 HIS B CD2 1 ATOM 6072 C CE1 . HIS B 1 392 ? 190.516 38.769 34.016 1.00 28.07 ? 390 HIS B CE1 1 ATOM 6073 N NE2 . HIS B 1 392 ? 190.838 39.161 32.787 1.00 28.83 ? 390 HIS B NE2 1 ATOM 6074 N N . ALA B 1 393 ? 187.217 44.558 34.719 1.00 22.68 ? 391 ALA B N 1 ATOM 6075 C CA . ALA B 1 393 ? 186.556 45.615 35.469 1.00 22.36 ? 391 ALA B CA 1 ATOM 6076 C C . ALA B 1 393 ? 185.065 45.284 35.609 1.00 28.14 ? 391 ALA B C 1 ATOM 6077 O O . ALA B 1 393 ? 184.532 45.303 36.720 1.00 26.58 ? 391 ALA B O 1 ATOM 6078 C CB . ALA B 1 393 ? 186.729 46.945 34.747 1.00 22.68 ? 391 ALA B CB 1 ATOM 6079 N N . LEU B 1 394 ? 184.403 44.944 34.474 1.00 26.81 ? 392 LEU B N 1 ATOM 6080 C CA . LEU B 1 394 ? 182.976 44.571 34.432 1.00 25.35 ? 392 LEU B CA 1 ATOM 6081 C C . LEU B 1 394 ? 182.709 43.264 35.148 1.00 30.62 ? 392 LEU B C 1 ATOM 6082 O O . LEU B 1 394 ? 181.652 43.110 35.734 1.00 30.65 ? 392 LEU B O 1 ATOM 6083 C CB . LEU B 1 394 ? 182.454 44.511 32.991 1.00 23.71 ? 392 LEU B CB 1 ATOM 6084 C CG . LEU B 1 394 ? 182.201 45.866 32.346 1.00 25.56 ? 392 LEU B CG 1 ATOM 6085 C CD1 . LEU B 1 394 ? 181.905 45.690 30.865 1.00 26.04 ? 392 LEU B CD1 1 ATOM 6086 C CD2 . LEU B 1 394 ? 181.062 46.614 33.044 1.00 20.66 ? 392 LEU B CD2 1 ATOM 6087 N N . HIS B 1 395 ? 183.665 42.340 35.123 1.00 28.76 ? 393 HIS B N 1 ATOM 6088 C CA . HIS B 1 395 ? 183.523 41.070 35.809 1.00 29.93 ? 393 HIS B CA 1 ATOM 6089 C C . HIS B 1 395 ? 183.584 41.316 37.313 1.00 34.07 ? 393 HIS B C 1 ATOM 6090 O O . HIS B 1 395 ? 182.696 40.890 38.042 1.00 35.92 ? 393 HIS B O 1 ATOM 6091 C CB . HIS B 1 395 ? 184.587 40.072 35.319 1.00 31.43 ? 393 HIS B CB 1 ATOM 6092 C CG . HIS B 1 395 ? 184.488 38.715 35.951 1.00 35.12 ? 393 HIS B CG 1 ATOM 6093 N ND1 . HIS B 1 395 ? 183.923 37.641 35.279 1.00 36.84 ? 393 HIS B ND1 1 ATOM 6094 C CD2 . HIS B 1 395 ? 184.892 38.301 37.175 1.00 36.05 ? 393 HIS B CD2 1 ATOM 6095 C CE1 . HIS B 1 395 ? 183.999 36.619 36.110 1.00 35.60 ? 393 HIS B CE1 1 ATOM 6096 N NE2 . HIS B 1 395 ? 184.569 36.973 37.265 1.00 35.89 ? 393 HIS B NE2 1 ATOM 6097 N N . ASN B 1 396 ? 184.592 42.062 37.763 1.00 29.20 ? 394 ASN B N 1 ATOM 6098 C CA . ASN B 1 396 ? 184.793 42.447 39.165 1.00 26.72 ? 394 ASN B CA 1 ATOM 6099 C C . ASN B 1 396 ? 183.610 43.237 39.728 1.00 30.20 ? 394 ASN B C 1 ATOM 6100 O O . ASN B 1 396 ? 183.204 42.972 40.859 1.00 32.13 ? 394 ASN B O 1 ATOM 6101 C CB . ASN B 1 396 ? 186.115 43.171 39.327 1.00 15.02 ? 394 ASN B CB 1 ATOM 6102 C CG . ASN B 1 396 ? 187.296 42.312 38.924 1.00 36.00 ? 394 ASN B CG 1 ATOM 6103 O OD1 . ASN B 1 396 ? 187.157 41.109 38.637 1.00 35.94 ? 394 ASN B OD1 1 ATOM 6104 N ND2 . ASN B 1 396 ? 188.489 42.918 38.811 1.00 23.21 ? 394 ASN B ND2 1 ATOM 6105 N N . MET B 1 397 ? 182.991 44.110 38.911 1.00 24.97 ? 395 MET B N 1 ATOM 6106 C CA . MET B 1 397 ? 181.813 44.879 39.304 1.00 24.89 ? 395 MET B CA 1 ATOM 6107 C C . MET B 1 397 ? 180.613 43.957 39.480 1.00 31.71 ? 395 MET B C 1 ATOM 6108 O O . MET B 1 397 ? 179.806 44.166 40.397 1.00 31.12 ? 395 MET B O 1 ATOM 6109 C CB . MET B 1 397 ? 181.495 45.974 38.292 1.00 27.00 ? 395 MET B CB 1 ATOM 6110 C CG . MET B 1 397 ? 180.303 46.796 38.708 1.00 30.90 ? 395 MET B CG 1 ATOM 6111 S SD . MET B 1 397 ? 179.914 48.171 37.616 1.00 34.99 ? 395 MET B SD 1 ATOM 6112 C CE . MET B 1 397 ? 180.402 49.504 38.619 1.00 31.06 ? 395 MET B CE 1 ATOM 6113 N N . HIS B 1 398 ? 180.503 42.944 38.589 1.00 29.32 ? 396 HIS B N 1 ATOM 6114 C CA . HIS B 1 398 ? 179.447 41.942 38.597 1.00 29.42 ? 396 HIS B CA 1 ATOM 6115 C C . HIS B 1 398 ? 179.510 41.137 39.874 1.00 32.72 ? 396 HIS B C 1 ATOM 6116 O O . HIS B 1 398 ? 178.484 41.017 40.524 1.00 31.05 ? 396 HIS B O 1 ATOM 6117 C CB . HIS B 1 398 ? 179.557 41.000 37.391 1.00 30.17 ? 396 HIS B CB 1 ATOM 6118 C CG . HIS B 1 398 ? 178.340 40.164 37.211 1.00 33.13 ? 396 HIS B CG 1 ATOM 6119 N ND1 . HIS B 1 398 ? 178.277 38.872 37.702 1.00 34.54 ? 396 HIS B ND1 1 ATOM 6120 C CD2 . HIS B 1 398 ? 177.157 40.482 36.635 1.00 34.22 ? 396 HIS B CD2 1 ATOM 6121 C CE1 . HIS B 1 398 ? 177.064 38.441 37.403 1.00 33.75 ? 396 HIS B CE1 1 ATOM 6122 N NE2 . HIS B 1 398 ? 176.359 39.373 36.747 1.00 34.23 ? 396 HIS B NE2 1 ATOM 6123 N N . ARG B 1 399 ? 180.717 40.625 40.256 1.00 30.05 ? 397 ARG B N 1 ATOM 6124 C CA . ARG B 1 399 ? 180.946 39.865 41.496 1.00 30.24 ? 397 ARG B CA 1 ATOM 6125 C C . ARG B 1 399 ? 180.410 40.652 42.691 1.00 36.73 ? 397 ARG B C 1 ATOM 6126 O O . ARG B 1 399 ? 179.723 40.107 43.551 1.00 38.93 ? 397 ARG B O 1 ATOM 6127 C CB . ARG B 1 399 ? 182.448 39.540 41.657 1.00 29.82 ? 397 ARG B CB 1 ATOM 6128 C CG . ARG B 1 399 ? 182.919 39.230 43.102 1.00 35.17 ? 397 ARG B CG 1 ATOM 6129 C CD . ARG B 1 399 ? 184.443 39.119 43.248 1.00 40.35 ? 397 ARG B CD 1 ATOM 6130 N NE . ARG B 1 399 ? 185.170 40.292 42.747 1.00 44.22 ? 397 ARG B NE 1 ATOM 6131 C CZ . ARG B 1 399 ? 185.358 41.402 43.449 1.00 61.03 ? 397 ARG B CZ 1 ATOM 6132 N NH1 . ARG B 1 399 ? 186.017 42.429 42.920 1.00 58.07 ? 397 ARG B NH1 1 ATOM 6133 N NH2 . ARG B 1 399 ? 184.909 41.490 44.688 1.00 45.03 ? 397 ARG B NH2 1 ATOM 6134 N N . ALA B 1 400 ? 180.670 41.945 42.699 1.00 33.17 ? 398 ALA B N 1 ATOM 6135 C CA . ALA B 1 400 ? 180.221 42.810 43.759 1.00 32.90 ? 398 ALA B CA 1 ATOM 6136 C C . ALA B 1 400 ? 178.719 43.199 43.679 1.00 38.16 ? 398 ALA B C 1 ATOM 6137 O O . ALA B 1 400 ? 178.059 43.278 44.706 1.00 36.89 ? 398 ALA B O 1 ATOM 6138 C CB . ALA B 1 400 ? 181.121 44.045 43.819 1.00 33.09 ? 398 ALA B CB 1 ATOM 6139 N N . LEU B 1 401 ? 178.179 43.448 42.491 1.00 38.10 ? 399 LEU B N 1 ATOM 6140 C CA . LEU B 1 401 ? 176.805 43.947 42.405 1.00 39.10 ? 399 LEU B CA 1 ATOM 6141 C C . LEU B 1 401 ? 175.716 42.901 42.126 1.00 45.04 ? 399 LEU B C 1 ATOM 6142 O O . LEU B 1 401 ? 174.547 43.177 42.422 1.00 43.59 ? 399 LEU B O 1 ATOM 6143 C CB . LEU B 1 401 ? 176.724 45.088 41.392 1.00 39.12 ? 399 LEU B CB 1 ATOM 6144 C CG . LEU B 1 401 ? 177.536 46.363 41.734 1.00 43.32 ? 399 LEU B CG 1 ATOM 6145 C CD1 . LEU B 1 401 ? 177.073 47.532 40.884 1.00 43.23 ? 399 LEU B CD1 1 ATOM 6146 C CD2 . LEU B 1 401 ? 177.410 46.747 43.206 1.00 43.01 ? 399 LEU B CD2 1 ATOM 6147 N N . CYS B 1 402 ? 176.101 41.706 41.620 1.00 44.13 ? 400 CYS B N 1 ATOM 6148 C CA . CYS B 1 402 ? 175.227 40.574 41.262 1.00 45.05 ? 400 CYS B CA 1 ATOM 6149 C C . CYS B 1 402 ? 175.794 39.288 41.884 1.00 46.63 ? 400 CYS B C 1 ATOM 6150 O O . CYS B 1 402 ? 176.233 38.394 41.145 1.00 45.00 ? 400 CYS B O 1 ATOM 6151 C CB . CYS B 1 402 ? 175.095 40.450 39.742 1.00 46.69 ? 400 CYS B CB 1 ATOM 6152 S SG . CYS B 1 402 ? 174.694 42.002 38.887 1.00 51.85 ? 400 CYS B SG 1 ATOM 6153 N N . PRO B 1 403 ? 175.804 39.165 43.236 1.00 43.44 ? 401 PRO B N 1 ATOM 6154 C CA . PRO B 1 403 ? 176.395 37.969 43.865 1.00 43.72 ? 401 PRO B CA 1 ATOM 6155 C C . PRO B 1 403 ? 175.686 36.622 43.642 1.00 49.61 ? 401 PRO B C 1 ATOM 6156 O O . PRO B 1 403 ? 176.339 35.570 43.687 1.00 48.12 ? 401 PRO B O 1 ATOM 6157 C CB . PRO B 1 403 ? 176.403 38.329 45.349 1.00 44.90 ? 401 PRO B CB 1 ATOM 6158 C CG . PRO B 1 403 ? 175.277 39.264 45.499 1.00 49.55 ? 401 PRO B CG 1 ATOM 6159 C CD . PRO B 1 403 ? 175.324 40.107 44.265 1.00 45.26 ? 401 PRO B CD 1 ATOM 6160 N N . ASN B 1 404 ? 174.365 36.647 43.433 1.00 48.21 ? 402 ASN B N 1 ATOM 6161 C CA . ASN B 1 404 ? 173.590 35.418 43.326 1.00 49.22 ? 402 ASN B CA 1 ATOM 6162 C C . ASN B 1 404 ? 173.402 34.900 41.886 1.00 51.64 ? 402 ASN B C 1 ATOM 6163 O O . ASN B 1 404 ? 172.750 33.877 41.678 1.00 50.42 ? 402 ASN B O 1 ATOM 6164 C CB . ASN B 1 404 ? 172.249 35.606 44.056 1.00 55.86 ? 402 ASN B CB 1 ATOM 6165 C CG . ASN B 1 404 ? 172.394 35.820 45.570 1.00 84.83 ? 402 ASN B CG 1 ATOM 6166 O OD1 . ASN B 1 404 ? 173.134 35.099 46.269 1.00 73.84 ? 402 ASN B OD1 1 ATOM 6167 N ND2 . ASN B 1 404 ? 171.670 36.808 46.118 1.00 76.25 ? 402 ASN B ND2 1 ATOM 6168 N N . THR B 1 405 ? 174.005 35.570 40.901 1.00 47.95 ? 403 THR B N 1 ATOM 6169 C CA . THR B 1 405 ? 173.843 35.191 39.493 1.00 46.54 ? 403 THR B CA 1 ATOM 6170 C C . THR B 1 405 ? 175.067 35.492 38.644 1.00 48.02 ? 403 THR B C 1 ATOM 6171 O O . THR B 1 405 ? 175.897 36.321 39.033 1.00 46.99 ? 403 THR B O 1 ATOM 6172 C CB . THR B 1 405 ? 172.557 35.840 38.898 1.00 49.23 ? 403 THR B CB 1 ATOM 6173 O OG1 . THR B 1 405 ? 172.385 35.405 37.546 1.00 52.58 ? 403 THR B OG1 1 ATOM 6174 C CG2 . THR B 1 405 ? 172.546 37.371 38.987 1.00 39.89 ? 403 THR B CG2 1 ATOM 6175 N N . THR B 1 406 ? 175.163 34.799 37.478 1.00 42.96 ? 404 THR B N 1 ATOM 6176 C CA . THR B 1 406 ? 176.192 35.012 36.453 1.00 41.28 ? 404 THR B CA 1 ATOM 6177 C C . THR B 1 406 ? 175.624 35.976 35.404 1.00 42.49 ? 404 THR B C 1 ATOM 6178 O O . THR B 1 406 ? 176.370 36.497 34.577 1.00 40.84 ? 404 THR B O 1 ATOM 6179 C CB . THR B 1 406 ? 176.629 33.706 35.791 1.00 44.36 ? 404 THR B CB 1 ATOM 6180 O OG1 . THR B 1 406 ? 175.524 33.102 35.121 1.00 42.05 ? 404 THR B OG1 1 ATOM 6181 C CG2 . THR B 1 406 ? 177.278 32.752 36.753 1.00 44.87 ? 404 THR B CG2 1 ATOM 6182 N N . ARG B 1 407 ? 174.297 36.199 35.439 1.00 38.52 ? 405 ARG B N 1 ATOM 6183 C CA . ARG B 1 407 ? 173.594 37.064 34.496 1.00 38.52 ? 405 ARG B CA 1 ATOM 6184 C C . ARG B 1 407 ? 173.531 38.469 35.001 1.00 43.65 ? 405 ARG B C 1 ATOM 6185 O O . ARG B 1 407 ? 173.673 38.695 36.199 1.00 44.07 ? 405 ARG B O 1 ATOM 6186 C CB . ARG B 1 407 ? 172.178 36.535 34.226 1.00 39.99 ? 405 ARG B CB 1 ATOM 6187 C CG . ARG B 1 407 ? 172.156 35.115 33.657 1.00 54.79 ? 405 ARG B CG 1 ATOM 6188 C CD . ARG B 1 407 ? 172.500 35.073 32.183 1.00 72.92 ? 405 ARG B CD 1 ATOM 6189 N NE . ARG B 1 407 ? 173.314 33.900 31.872 1.00 90.27 ? 405 ARG B NE 1 ATOM 6190 C CZ . ARG B 1 407 ? 173.168 33.151 30.784 1.00 102.87 ? 405 ARG B CZ 1 ATOM 6191 N NH1 . ARG B 1 407 ? 172.233 33.446 29.887 1.00 88.67 ? 405 ARG B NH1 1 ATOM 6192 N NH2 . ARG B 1 407 ? 173.953 32.100 30.586 1.00 86.56 ? 405 ARG B NH2 1 ATOM 6193 N N . LEU B 1 408 ? 173.327 39.421 34.091 1.00 41.31 ? 406 LEU B N 1 ATOM 6194 C CA . LEU B 1 408 ? 173.215 40.833 34.419 1.00 41.26 ? 406 LEU B CA 1 ATOM 6195 C C . LEU B 1 408 ? 171.999 41.070 35.328 1.00 46.99 ? 406 LEU B C 1 ATOM 6196 O O . LEU B 1 408 ? 170.861 40.961 34.883 1.00 46.49 ? 406 LEU B O 1 ATOM 6197 C CB . LEU B 1 408 ? 173.076 41.664 33.130 1.00 40.93 ? 406 LEU B CB 1 ATOM 6198 C CG . LEU B 1 408 ? 174.223 42.572 32.662 1.00 44.21 ? 406 LEU B CG 1 ATOM 6199 C CD1 . LEU B 1 408 ? 173.727 43.515 31.564 1.00 43.46 ? 406 LEU B CD1 1 ATOM 6200 C CD2 . LEU B 1 408 ? 174.788 43.408 33.790 1.00 44.17 ? 406 LEU B CD2 1 ATOM 6201 N N . CYS B 1 409 ? 172.248 41.356 36.607 1.00 45.91 ? 407 CYS B N 1 ATOM 6202 C CA . CYS B 1 409 ? 171.198 41.649 37.581 1.00 47.05 ? 407 CYS B CA 1 ATOM 6203 C C . CYS B 1 409 ? 170.800 43.118 37.421 1.00 53.74 ? 407 CYS B C 1 ATOM 6204 O O . CYS B 1 409 ? 171.506 43.882 36.749 1.00 53.26 ? 407 CYS B O 1 ATOM 6205 C CB . CYS B 1 409 ? 171.666 41.336 39.003 1.00 47.99 ? 407 CYS B CB 1 ATOM 6206 S SG . CYS B 1 409 ? 172.875 42.522 39.685 1.00 52.44 ? 407 CYS B SG 1 ATOM 6207 N N . ASP B 1 410 ? 169.694 43.520 38.057 1.00 53.16 ? 408 ASP B N 1 ATOM 6208 C CA . ASP B 1 410 ? 169.176 44.879 37.981 1.00 54.35 ? 408 ASP B CA 1 ATOM 6209 C C . ASP B 1 410 ? 170.110 45.934 38.556 1.00 58.19 ? 408 ASP B C 1 ATOM 6210 O O . ASP B 1 410 ? 170.122 47.081 38.069 1.00 58.55 ? 408 ASP B O 1 ATOM 6211 C CB . ASP B 1 410 ? 167.787 44.967 38.617 1.00 57.23 ? 408 ASP B CB 1 ATOM 6212 C CG . ASP B 1 410 ? 166.664 44.553 37.679 1.00 74.96 ? 408 ASP B CG 1 ATOM 6213 O OD1 . ASP B 1 410 ? 166.966 44.148 36.520 1.00 75.12 ? 408 ASP B OD1 1 ATOM 6214 O OD2 . ASP B 1 410 ? 165.481 44.661 38.086 1.00 83.58 ? 408 ASP B OD2 1 ATOM 6215 N N . ALA B 1 411 ? 170.930 45.538 39.543 1.00 53.09 ? 409 ALA B N 1 ATOM 6216 C CA . ALA B 1 411 ? 171.889 46.427 40.193 1.00 52.07 ? 409 ALA B CA 1 ATOM 6217 C C . ALA B 1 411 ? 172.943 47.004 39.225 1.00 54.93 ? 409 ALA B C 1 ATOM 6218 O O . ALA B 1 411 ? 173.571 48.006 39.552 1.00 55.86 ? 409 ALA B O 1 ATOM 6219 C CB . ALA B 1 411 ? 172.552 45.710 41.353 1.00 52.73 ? 409 ALA B CB 1 ATOM 6220 N N . MET B 1 412 ? 173.089 46.402 38.023 1.00 49.41 ? 410 MET B N 1 ATOM 6221 C CA . MET B 1 412 ? 174.033 46.775 36.965 1.00 47.31 ? 410 MET B CA 1 ATOM 6222 C C . MET B 1 412 ? 173.331 47.152 35.658 1.00 49.84 ? 410 MET B C 1 ATOM 6223 O O . MET B 1 412 ? 173.925 47.047 34.581 1.00 49.59 ? 410 MET B O 1 ATOM 6224 C CB . MET B 1 412 ? 175.007 45.627 36.723 1.00 49.39 ? 410 MET B CB 1 ATOM 6225 C CG . MET B 1 412 ? 176.411 45.996 36.946 1.00 53.27 ? 410 MET B CG 1 ATOM 6226 S SD . MET B 1 412 ? 177.388 44.502 36.838 1.00 58.48 ? 410 MET B SD 1 ATOM 6227 C CE . MET B 1 412 ? 178.728 45.062 35.750 1.00 55.54 ? 410 MET B CE 1 ATOM 6228 N N . ARG B 1 413 ? 172.061 47.577 35.749 1.00 45.66 ? 411 ARG B N 1 ATOM 6229 C CA . ARG B 1 413 ? 171.273 48.041 34.610 1.00 44.61 ? 411 ARG B CA 1 ATOM 6230 C C . ARG B 1 413 ? 170.741 49.427 35.030 1.00 48.99 ? 411 ARG B C 1 ATOM 6231 O O . ARG B 1 413 ? 169.819 49.507 35.850 1.00 50.33 ? 411 ARG B O 1 ATOM 6232 C CB . ARG B 1 413 ? 170.129 47.070 34.262 1.00 43.08 ? 411 ARG B CB 1 ATOM 6233 C CG . ARG B 1 413 ? 170.543 45.693 33.741 1.00 53.35 ? 411 ARG B CG 1 ATOM 6234 C CD . ARG B 1 413 ? 169.312 44.896 33.339 1.00 61.20 ? 411 ARG B CD 1 ATOM 6235 N NE . ARG B 1 413 ? 169.564 43.460 33.193 1.00 71.81 ? 411 ARG B NE 1 ATOM 6236 C CZ . ARG B 1 413 ? 169.471 42.789 32.046 1.00 91.05 ? 411 ARG B CZ 1 ATOM 6237 N NH1 . ARG B 1 413 ? 169.150 43.421 30.922 1.00 80.98 ? 411 ARG B NH1 1 ATOM 6238 N NH2 . ARG B 1 413 ? 169.700 41.480 32.013 1.00 76.45 ? 411 ARG B NH2 1 ATOM 6239 N N . PRO B 1 414 ? 171.372 50.539 34.579 1.00 43.42 ? 412 PRO B N 1 ATOM 6240 C CA . PRO B 1 414 ? 172.558 50.604 33.709 1.00 41.11 ? 412 PRO B CA 1 ATOM 6241 C C . PRO B 1 414 ? 173.831 50.521 34.570 1.00 38.77 ? 412 PRO B C 1 ATOM 6242 O O . PRO B 1 414 ? 173.759 50.622 35.798 1.00 36.32 ? 412 PRO B O 1 ATOM 6243 C CB . PRO B 1 414 ? 172.398 51.978 33.050 1.00 42.61 ? 412 PRO B CB 1 ATOM 6244 C CG . PRO B 1 414 ? 171.781 52.841 34.156 1.00 47.69 ? 412 PRO B CG 1 ATOM 6245 C CD . PRO B 1 414 ? 170.943 51.897 35.006 1.00 44.37 ? 412 PRO B CD 1 ATOM 6246 N N . VAL B 1 415 ? 174.985 50.336 33.935 1.00 33.20 ? 413 VAL B N 1 ATOM 6247 C CA . VAL B 1 415 ? 176.252 50.338 34.659 1.00 32.36 ? 413 VAL B CA 1 ATOM 6248 C C . VAL B 1 415 ? 176.598 51.826 34.943 1.00 35.23 ? 413 VAL B C 1 ATOM 6249 O O . VAL B 1 415 ? 176.444 52.682 34.055 1.00 36.75 ? 413 VAL B O 1 ATOM 6250 C CB . VAL B 1 415 ? 177.372 49.591 33.887 1.00 36.00 ? 413 VAL B CB 1 ATOM 6251 C CG1 . VAL B 1 415 ? 178.718 49.720 34.588 1.00 35.58 ? 413 VAL B CG1 1 ATOM 6252 C CG2 . VAL B 1 415 ? 177.017 48.124 33.670 1.00 35.66 ? 413 VAL B CG2 1 ATOM 6253 N N . ASN B 1 416 ? 176.991 52.126 36.198 1.00 27.74 ? 414 ASN B N 1 ATOM 6254 C CA . ASN B 1 416 ? 177.379 53.457 36.640 1.00 25.19 ? 414 ASN B CA 1 ATOM 6255 C C . ASN B 1 416 ? 178.845 53.657 36.277 1.00 27.50 ? 414 ASN B C 1 ATOM 6256 O O . ASN B 1 416 ? 179.720 52.987 36.846 1.00 26.29 ? 414 ASN B O 1 ATOM 6257 C CB . ASN B 1 416 ? 177.203 53.580 38.133 1.00 22.09 ? 414 ASN B CB 1 ATOM 6258 C CG . ASN B 1 416 ? 177.281 54.994 38.582 1.00 45.92 ? 414 ASN B CG 1 ATOM 6259 O OD1 . ASN B 1 416 ? 178.312 55.460 39.077 1.00 34.05 ? 414 ASN B OD1 1 ATOM 6260 N ND2 . ASN B 1 416 ? 176.200 55.726 38.350 1.00 44.74 ? 414 ASN B ND2 1 ATOM 6261 N N . GLY B 1 417 ? 179.093 54.539 35.308 1.00 23.83 ? 415 GLY B N 1 ATOM 6262 C CA . GLY B 1 417 ? 180.427 54.822 34.782 1.00 23.63 ? 415 GLY B CA 1 ATOM 6263 C C . GLY B 1 417 ? 181.445 55.260 35.807 1.00 29.02 ? 415 GLY B C 1 ATOM 6264 O O . GLY B 1 417 ? 182.572 54.749 35.803 1.00 28.59 ? 415 GLY B O 1 ATOM 6265 N N . ARG B 1 418 ? 181.041 56.196 36.709 1.00 27.67 ? 416 ARG B N 1 ATOM 6266 C CA . ARG B 1 418 ? 181.884 56.734 37.791 1.00 27.89 ? 416 ARG B CA 1 ATOM 6267 C C . ARG B 1 418 ? 182.475 55.586 38.627 1.00 32.35 ? 416 ARG B C 1 ATOM 6268 O O . ARG B 1 418 ? 183.698 55.481 38.776 1.00 32.93 ? 416 ARG B O 1 ATOM 6269 C CB . ARG B 1 418 ? 181.073 57.717 38.652 1.00 28.63 ? 416 ARG B CB 1 ATOM 6270 C CG . ARG B 1 418 ? 181.734 58.166 39.947 1.00 43.22 ? 416 ARG B CG 1 ATOM 6271 C CD . ARG B 1 418 ? 182.553 59.427 39.833 1.00 59.38 ? 416 ARG B CD 1 ATOM 6272 N NE . ARG B 1 418 ? 183.222 59.720 41.103 1.00 77.48 ? 416 ARG B NE 1 ATOM 6273 C CZ . ARG B 1 418 ? 184.348 60.419 41.224 1.00 98.35 ? 416 ARG B CZ 1 ATOM 6274 N NH1 . ARG B 1 418 ? 184.886 60.619 42.421 1.00 83.45 ? 416 ARG B NH1 1 ATOM 6275 N NH2 . ARG B 1 418 ? 184.951 60.916 40.147 1.00 89.41 ? 416 ARG B NH2 1 ATOM 6276 N N . ARG B 1 419 ? 181.599 54.693 39.094 1.00 27.84 ? 417 ARG B N 1 ATOM 6277 C CA . ARG B 1 419 ? 181.938 53.516 39.884 1.00 27.05 ? 417 ARG B CA 1 ATOM 6278 C C . ARG B 1 419 ? 182.782 52.546 39.048 1.00 29.43 ? 417 ARG B C 1 ATOM 6279 O O . ARG B 1 419 ? 183.817 52.053 39.513 1.00 28.90 ? 417 ARG B O 1 ATOM 6280 C CB . ARG B 1 419 ? 180.655 52.826 40.351 1.00 24.41 ? 417 ARG B CB 1 ATOM 6281 C CG . ARG B 1 419 ? 179.895 53.611 41.396 1.00 30.30 ? 417 ARG B CG 1 ATOM 6282 C CD . ARG B 1 419 ? 178.581 52.902 41.706 1.00 54.43 ? 417 ARG B CD 1 ATOM 6283 N NE . ARG B 1 419 ? 178.766 51.732 42.569 1.00 63.49 ? 417 ARG B NE 1 ATOM 6284 C CZ . ARG B 1 419 ? 177.797 50.913 42.967 1.00 68.03 ? 417 ARG B CZ 1 ATOM 6285 N NH1 . ARG B 1 419 ? 176.544 51.114 42.577 1.00 43.39 ? 417 ARG B NH1 1 ATOM 6286 N NH2 . ARG B 1 419 ? 178.074 49.889 43.759 1.00 57.35 ? 417 ARG B NH2 1 ATOM 6287 N N . LEU B 1 420 ? 182.371 52.311 37.799 1.00 23.62 ? 418 LEU B N 1 ATOM 6288 C CA . LEU B 1 420 ? 183.136 51.422 36.938 1.00 22.19 ? 418 LEU B CA 1 ATOM 6289 C C . LEU B 1 420 ? 184.604 51.898 36.818 1.00 26.09 ? 418 LEU B C 1 ATOM 6290 O O . LEU B 1 420 ? 185.522 51.136 37.158 1.00 22.83 ? 418 LEU B O 1 ATOM 6291 C CB . LEU B 1 420 ? 182.449 51.243 35.564 1.00 21.03 ? 418 LEU B CB 1 ATOM 6292 C CG . LEU B 1 420 ? 183.146 50.324 34.561 1.00 23.02 ? 418 LEU B CG 1 ATOM 6293 C CD1 . LEU B 1 420 ? 183.449 48.938 35.172 1.00 23.75 ? 418 LEU B CD1 1 ATOM 6294 C CD2 . LEU B 1 420 ? 182.343 50.198 33.319 1.00 19.09 ? 418 LEU B CD2 1 ATOM 6295 N N . TYR B 1 421 ? 184.810 53.189 36.447 1.00 23.44 ? 419 TYR B N 1 ATOM 6296 C CA . TYR B 1 421 ? 186.158 53.719 36.308 1.00 22.99 ? 419 TYR B CA 1 ATOM 6297 C C . TYR B 1 421 ? 186.939 53.732 37.640 1.00 28.50 ? 419 TYR B C 1 ATOM 6298 O O . TYR B 1 421 ? 187.963 53.038 37.755 1.00 27.60 ? 419 TYR B O 1 ATOM 6299 C CB . TYR B 1 421 ? 186.144 55.098 35.624 1.00 23.81 ? 419 TYR B CB 1 ATOM 6300 C CG . TYR B 1 421 ? 187.529 55.695 35.428 1.00 24.42 ? 419 TYR B CG 1 ATOM 6301 C CD1 . TYR B 1 421 ? 188.307 55.362 34.316 1.00 27.17 ? 419 TYR B CD1 1 ATOM 6302 C CD2 . TYR B 1 421 ? 188.057 56.590 36.348 1.00 23.47 ? 419 TYR B CD2 1 ATOM 6303 C CE1 . TYR B 1 421 ? 189.578 55.906 34.139 1.00 30.31 ? 419 TYR B CE1 1 ATOM 6304 C CE2 . TYR B 1 421 ? 189.336 57.107 36.201 1.00 24.10 ? 419 TYR B CE2 1 ATOM 6305 C CZ . TYR B 1 421 ? 190.078 56.799 35.080 1.00 36.78 ? 419 TYR B CZ 1 ATOM 6306 O OH . TYR B 1 421 ? 191.322 57.369 34.974 1.00 40.07 ? 419 TYR B OH 1 ATOM 6307 N N . LYS B 1 422 ? 186.429 54.503 38.634 1.00 25.48 ? 420 LYS B N 1 ATOM 6308 C CA . LYS B 1 422 ? 187.026 54.716 39.944 1.00 25.14 ? 420 LYS B CA 1 ATOM 6309 C C . LYS B 1 422 ? 187.264 53.446 40.782 1.00 31.15 ? 420 LYS B C 1 ATOM 6310 O O . LYS B 1 422 ? 188.379 53.247 41.286 1.00 32.19 ? 420 LYS B O 1 ATOM 6311 C CB . LYS B 1 422 ? 186.196 55.723 40.741 1.00 26.67 ? 420 LYS B CB 1 ATOM 6312 C CG . LYS B 1 422 ? 186.914 57.024 41.013 1.00 42.36 ? 420 LYS B CG 1 ATOM 6313 N N . ASP B 1 423 ? 186.237 52.598 40.937 1.00 26.88 ? 421 ASP B N 1 ATOM 6314 C CA . ASP B 1 423 ? 186.320 51.417 41.806 1.00 26.79 ? 421 ASP B CA 1 ATOM 6315 C C . ASP B 1 423 ? 186.732 50.106 41.133 1.00 30.85 ? 421 ASP B C 1 ATOM 6316 O O . ASP B 1 423 ? 187.137 49.162 41.831 1.00 30.58 ? 421 ASP B O 1 ATOM 6317 C CB . ASP B 1 423 ? 184.985 51.225 42.545 1.00 28.51 ? 421 ASP B CB 1 ATOM 6318 C CG . ASP B 1 423 ? 184.507 52.467 43.294 1.00 39.35 ? 421 ASP B CG 1 ATOM 6319 O OD1 . ASP B 1 423 ? 185.372 53.304 43.684 1.00 37.71 ? 421 ASP B OD1 1 ATOM 6320 O OD2 . ASP B 1 423 ? 183.271 52.586 43.530 1.00 46.24 ? 421 ASP B OD2 1 ATOM 6321 N N . PHE B 1 424 ? 186.658 50.033 39.791 1.00 27.20 ? 422 PHE B N 1 ATOM 6322 C CA . PHE B 1 424 ? 186.953 48.770 39.122 1.00 25.39 ? 422 PHE B CA 1 ATOM 6323 C C . PHE B 1 424 ? 188.028 48.877 38.047 1.00 28.04 ? 422 PHE B C 1 ATOM 6324 O O . PHE B 1 424 ? 188.987 48.113 38.105 1.00 27.33 ? 422 PHE B O 1 ATOM 6325 C CB . PHE B 1 424 ? 185.643 48.111 38.602 1.00 25.64 ? 422 PHE B CB 1 ATOM 6326 C CG . PHE B 1 424 ? 184.642 47.843 39.720 1.00 25.70 ? 422 PHE B CG 1 ATOM 6327 C CD1 . PHE B 1 424 ? 184.765 46.716 40.538 1.00 27.30 ? 422 PHE B CD1 1 ATOM 6328 C CD2 . PHE B 1 424 ? 183.640 48.771 40.024 1.00 26.34 ? 422 PHE B CD2 1 ATOM 6329 C CE1 . PHE B 1 424 ? 183.861 46.494 41.602 1.00 27.50 ? 422 PHE B CE1 1 ATOM 6330 C CE2 . PHE B 1 424 ? 182.750 48.554 41.093 1.00 27.93 ? 422 PHE B CE2 1 ATOM 6331 C CZ . PHE B 1 424 ? 182.855 47.409 41.866 1.00 25.54 ? 422 PHE B CZ 1 ATOM 6332 N N . VAL B 1 425 ? 187.912 49.815 37.107 1.00 25.74 ? 423 VAL B N 1 ATOM 6333 C CA . VAL B 1 425 ? 188.880 49.919 35.996 1.00 26.16 ? 423 VAL B CA 1 ATOM 6334 C C . VAL B 1 425 ? 190.287 50.188 36.544 1.00 31.43 ? 423 VAL B C 1 ATOM 6335 O O . VAL B 1 425 ? 191.194 49.386 36.285 1.00 31.86 ? 423 VAL B O 1 ATOM 6336 C CB . VAL B 1 425 ? 188.457 50.904 34.853 1.00 29.64 ? 423 VAL B CB 1 ATOM 6337 C CG1 . VAL B 1 425 ? 189.575 51.105 33.842 1.00 29.42 ? 423 VAL B CG1 1 ATOM 6338 C CG2 . VAL B 1 425 ? 187.195 50.427 34.146 1.00 29.24 ? 423 VAL B CG2 1 ATOM 6339 N N . LEU B 1 426 ? 190.440 51.252 37.373 1.00 25.95 ? 424 LEU B N 1 ATOM 6340 C CA . LEU B 1 426 ? 191.722 51.611 37.964 1.00 24.52 ? 424 LEU B CA 1 ATOM 6341 C C . LEU B 1 426 ? 192.320 50.527 38.893 1.00 29.60 ? 424 LEU B C 1 ATOM 6342 O O . LEU B 1 426 ? 193.530 50.545 39.160 1.00 30.31 ? 424 LEU B O 1 ATOM 6343 C CB . LEU B 1 426 ? 191.623 52.957 38.702 1.00 23.67 ? 424 LEU B CB 1 ATOM 6344 C CG . LEU B 1 426 ? 191.362 54.263 37.886 1.00 24.58 ? 424 LEU B CG 1 ATOM 6345 C CD1 . LEU B 1 426 ? 191.253 55.464 38.835 1.00 21.93 ? 424 LEU B CD1 1 ATOM 6346 C CD2 . LEU B 1 426 ? 192.391 54.477 36.675 1.00 16.56 ? 424 LEU B CD2 1 ATOM 6347 N N . ASN B 1 427 ? 191.496 49.571 39.330 1.00 25.20 ? 425 ASN B N 1 ATOM 6348 C CA . ASN B 1 427 ? 191.924 48.531 40.259 1.00 25.32 ? 425 ASN B CA 1 ATOM 6349 C C . ASN B 1 427 ? 192.159 47.139 39.661 1.00 29.67 ? 425 ASN B C 1 ATOM 6350 O O . ASN B 1 427 ? 192.535 46.237 40.400 1.00 30.21 ? 425 ASN B O 1 ATOM 6351 C CB . ASN B 1 427 ? 190.928 48.444 41.422 1.00 25.54 ? 425 ASN B CB 1 ATOM 6352 C CG . ASN B 1 427 ? 190.941 49.670 42.273 1.00 43.66 ? 425 ASN B CG 1 ATOM 6353 O OD1 . ASN B 1 427 ? 192.011 50.251 42.524 1.00 47.19 ? 425 ASN B OD1 1 ATOM 6354 N ND2 . ASN B 1 427 ? 189.753 50.111 42.707 1.00 26.04 ? 425 ASN B ND2 1 ATOM 6355 N N . VAL B 1 428 ? 191.948 46.948 38.370 1.00 26.42 ? 426 VAL B N 1 ATOM 6356 C CA . VAL B 1 428 ? 192.199 45.646 37.761 1.00 26.41 ? 426 VAL B CA 1 ATOM 6357 C C . VAL B 1 428 ? 193.692 45.245 37.935 1.00 31.50 ? 426 VAL B C 1 ATOM 6358 O O . VAL B 1 428 ? 194.572 46.115 37.920 1.00 29.70 ? 426 VAL B O 1 ATOM 6359 C CB . VAL B 1 428 ? 191.753 45.538 36.264 1.00 29.55 ? 426 VAL B CB 1 ATOM 6360 C CG1 . VAL B 1 428 ? 190.242 45.658 36.094 1.00 28.98 ? 426 VAL B CG1 1 ATOM 6361 C CG2 . VAL B 1 428 ? 192.476 46.544 35.383 1.00 29.25 ? 426 VAL B CG2 1 ATOM 6362 N N . LYS B 1 429 ? 193.946 43.919 38.125 1.00 29.22 ? 427 LYS B N 1 ATOM 6363 C CA . LYS B 1 429 ? 195.269 43.304 38.204 1.00 29.60 ? 427 LYS B CA 1 ATOM 6364 C C . LYS B 1 429 ? 195.085 41.848 37.768 1.00 35.06 ? 427 LYS B C 1 ATOM 6365 O O . LYS B 1 429 ? 194.505 41.039 38.488 1.00 37.15 ? 427 LYS B O 1 ATOM 6366 C CB . LYS B 1 429 ? 195.903 43.442 39.609 1.00 32.09 ? 427 LYS B CB 1 ATOM 6367 C CG . LYS B 1 429 ? 197.413 43.229 39.659 1.00 41.19 ? 427 LYS B CG 1 ATOM 6368 C CD . LYS B 1 429 ? 197.898 43.099 41.102 1.00 49.87 ? 427 LYS B CD 1 ATOM 6369 C CE . LYS B 1 429 ? 199.351 42.690 41.182 1.00 68.13 ? 427 LYS B CE 1 ATOM 6370 N NZ . LYS B 1 429 ? 199.676 41.961 42.443 1.00 77.15 ? 427 LYS B NZ 1 ATOM 6371 N N . PHE B 1 430 ? 195.490 41.545 36.555 1.00 30.23 ? 428 PHE B N 1 ATOM 6372 C CA . PHE B 1 430 ? 195.373 40.202 36.001 1.00 29.87 ? 428 PHE B CA 1 ATOM 6373 C C . PHE B 1 430 ? 196.501 39.948 35.004 1.00 36.12 ? 428 PHE B C 1 ATOM 6374 O O . PHE B 1 430 ? 196.969 40.890 34.354 1.00 34.25 ? 428 PHE B O 1 ATOM 6375 C CB . PHE B 1 430 ? 193.994 39.973 35.359 1.00 30.98 ? 428 PHE B CB 1 ATOM 6376 C CG . PHE B 1 430 ? 193.732 40.841 34.151 1.00 32.06 ? 428 PHE B CG 1 ATOM 6377 C CD1 . PHE B 1 430 ? 193.209 42.125 34.297 1.00 34.15 ? 428 PHE B CD1 1 ATOM 6378 C CD2 . PHE B 1 430 ? 194.012 40.378 32.866 1.00 32.74 ? 428 PHE B CD2 1 ATOM 6379 C CE1 . PHE B 1 430 ? 193.003 42.938 33.190 1.00 34.52 ? 428 PHE B CE1 1 ATOM 6380 C CE2 . PHE B 1 430 ? 193.804 41.193 31.763 1.00 35.86 ? 428 PHE B CE2 1 ATOM 6381 C CZ . PHE B 1 430 ? 193.298 42.468 31.932 1.00 34.05 ? 428 PHE B CZ 1 ATOM 6382 N N . ASP B 1 431 ? 196.934 38.680 34.882 1.00 36.23 ? 429 ASP B N 1 ATOM 6383 C CA . ASP B 1 431 ? 198.009 38.342 33.947 1.00 37.81 ? 429 ASP B CA 1 ATOM 6384 C C . ASP B 1 431 ? 197.509 38.520 32.518 1.00 40.72 ? 429 ASP B C 1 ATOM 6385 O O . ASP B 1 431 ? 196.410 38.042 32.163 1.00 39.28 ? 429 ASP B O 1 ATOM 6386 C CB . ASP B 1 431 ? 198.548 36.911 34.147 1.00 40.95 ? 429 ASP B CB 1 ATOM 6387 C CG . ASP B 1 431 ? 198.750 36.457 35.579 1.00 57.84 ? 429 ASP B CG 1 ATOM 6388 O OD1 . ASP B 1 431 ? 199.633 37.043 36.280 1.00 59.61 ? 429 ASP B OD1 1 ATOM 6389 O OD2 . ASP B 1 431 ? 198.090 35.462 35.981 1.00 64.36 ? 429 ASP B OD2 1 ATOM 6390 N N . ALA B 1 432 ? 198.312 39.263 31.728 1.00 36.50 ? 430 ALA B N 1 ATOM 6391 C CA . ALA B 1 432 ? 198.036 39.567 30.334 1.00 35.81 ? 430 ALA B CA 1 ATOM 6392 C C . ALA B 1 432 ? 197.735 38.275 29.551 1.00 39.67 ? 430 ALA B C 1 ATOM 6393 O O . ALA B 1 432 ? 198.554 37.346 29.588 1.00 38.03 ? 430 ALA B O 1 ATOM 6394 C CB . ALA B 1 432 ? 199.224 40.299 29.716 1.00 36.04 ? 430 ALA B CB 1 ATOM 6395 N N . PRO B 1 433 ? 196.555 38.152 28.875 1.00 36.13 ? 431 PRO B N 1 ATOM 6396 C CA . PRO B 1 433 ? 196.326 36.944 28.058 1.00 36.21 ? 431 PRO B CA 1 ATOM 6397 C C . PRO B 1 433 ? 197.475 36.758 27.045 1.00 42.09 ? 431 PRO B C 1 ATOM 6398 O O . PRO B 1 433 ? 198.033 37.759 26.549 1.00 42.40 ? 431 PRO B O 1 ATOM 6399 C CB . PRO B 1 433 ? 194.984 37.238 27.358 1.00 36.70 ? 431 PRO B CB 1 ATOM 6400 C CG . PRO B 1 433 ? 194.787 38.676 27.456 1.00 39.54 ? 431 PRO B CG 1 ATOM 6401 C CD . PRO B 1 433 ? 195.458 39.128 28.705 1.00 35.64 ? 431 PRO B CD 1 ATOM 6402 N N . PHE B 1 434 ? 197.849 35.493 26.745 1.00 38.11 ? 432 PHE B N 1 ATOM 6403 C CA . PHE B 1 434 ? 198.901 35.145 25.746 1.00 36.01 ? 432 PHE B CA 1 ATOM 6404 C C . PHE B 1 434 ? 200.329 35.627 26.120 1.00 63.10 ? 432 PHE B C 1 ATOM 6405 O O . PHE B 1 434 ? 200.630 35.929 27.281 1.00 46.94 ? 432 PHE B O 1 ATOM 6406 C CB . PHE B 1 434 ? 198.517 35.635 24.306 1.00 36.61 ? 432 PHE B CB 1 ATOM 6407 C CG . PHE B 1 434 ? 197.043 35.566 23.949 1.00 36.68 ? 432 PHE B CG 1 ATOM 6408 C CD1 . PHE B 1 434 ? 196.473 34.382 23.495 1.00 38.85 ? 432 PHE B CD1 1 ATOM 6409 C CD2 . PHE B 1 434 ? 196.229 36.692 24.057 1.00 38.93 ? 432 PHE B CD2 1 ATOM 6410 C CE1 . PHE B 1 434 ? 195.107 34.311 23.188 1.00 40.02 ? 432 PHE B CE1 1 ATOM 6411 C CE2 . PHE B 1 434 ? 194.854 36.618 23.778 1.00 41.76 ? 432 PHE B CE2 1 ATOM 6412 C CZ . PHE B 1 434 ? 194.304 35.427 23.341 1.00 40.04 ? 432 PHE B CZ 1 ATOM 6413 N N . ALA B 1 437 ? 202.238 35.027 29.403 1.00 74.34 ? 435 ALA B N 1 ATOM 6414 C CA . ALA B 1 437 ? 202.821 34.217 30.475 1.00 74.80 ? 435 ALA B CA 1 ATOM 6415 C C . ALA B 1 437 ? 202.284 34.658 31.848 1.00 80.25 ? 435 ALA B C 1 ATOM 6416 O O . ALA B 1 437 ? 202.398 35.836 32.218 1.00 79.74 ? 435 ALA B O 1 ATOM 6417 C CB . ALA B 1 437 ? 204.344 34.298 30.438 1.00 75.39 ? 435 ALA B CB 1 ATOM 6418 N N . ASP B 1 438 ? 201.692 33.706 32.597 1.00 77.35 ? 436 ASP B N 1 ATOM 6419 C CA . ASP B 1 438 ? 201.070 33.967 33.900 1.00 77.70 ? 436 ASP B CA 1 ATOM 6420 C C . ASP B 1 438 ? 202.076 34.185 35.058 1.00 82.36 ? 436 ASP B C 1 ATOM 6421 O O . ASP B 1 438 ? 201.779 33.842 36.209 1.00 81.62 ? 436 ASP B O 1 ATOM 6422 C CB . ASP B 1 438 ? 200.051 32.865 34.239 1.00 79.61 ? 436 ASP B CB 1 ATOM 6423 N N . THR B 1 439 ? 203.235 34.804 34.763 1.00 79.67 ? 437 THR B N 1 ATOM 6424 C CA . THR B 1 439 ? 204.253 35.075 35.775 1.00 79.78 ? 437 THR B CA 1 ATOM 6425 C C . THR B 1 439 ? 203.909 36.377 36.541 1.00 85.08 ? 437 THR B C 1 ATOM 6426 O O . THR B 1 439 ? 203.031 36.358 37.415 1.00 84.79 ? 437 THR B O 1 ATOM 6427 C CB . THR B 1 439 ? 205.698 35.017 35.192 1.00 86.25 ? 437 THR B CB 1 ATOM 6428 O OG1 . THR B 1 439 ? 205.921 36.066 34.245 1.00 84.81 ? 437 THR B OG1 1 ATOM 6429 C CG2 . THR B 1 439 ? 206.036 33.672 34.569 1.00 84.64 ? 437 THR B CG2 1 ATOM 6430 N N . HIS B 1 440 ? 204.594 37.505 36.206 1.00 81.51 ? 438 HIS B N 1 ATOM 6431 C CA . HIS B 1 440 ? 204.473 38.795 36.894 1.00 80.38 ? 438 HIS B CA 1 ATOM 6432 C C . HIS B 1 440 ? 204.473 40.005 35.926 1.00 77.08 ? 438 HIS B C 1 ATOM 6433 O O . HIS B 1 440 ? 204.763 41.133 36.340 1.00 76.00 ? 438 HIS B O 1 ATOM 6434 C CB . HIS B 1 440 ? 205.563 38.907 37.988 1.00 82.32 ? 438 HIS B CB 1 ATOM 6435 C CG . HIS B 1 440 ? 205.454 37.822 39.023 1.00 86.91 ? 438 HIS B CG 1 ATOM 6436 N ND1 . HIS B 1 440 ? 204.390 37.786 39.921 1.00 89.33 ? 438 HIS B ND1 1 ATOM 6437 C CD2 . HIS B 1 440 ? 206.350 36.867 39.373 1.00 89.20 ? 438 HIS B CD2 1 ATOM 6438 C CE1 . HIS B 1 440 ? 204.644 36.775 40.740 1.00 88.93 ? 438 HIS B CE1 1 ATOM 6439 N NE2 . HIS B 1 440 ? 205.813 36.192 40.452 1.00 89.20 ? 438 HIS B NE2 1 ATOM 6440 N N . ASN B 1 441 ? 204.114 39.762 34.641 1.00 68.28 ? 439 ASN B N 1 ATOM 6441 C CA . ASN B 1 441 ? 203.917 40.809 33.623 1.00 65.03 ? 439 ASN B CA 1 ATOM 6442 C C . ASN B 1 441 ? 202.376 40.921 33.491 1.00 60.45 ? 439 ASN B C 1 ATOM 6443 O O . ASN B 1 441 ? 201.724 40.144 32.795 1.00 58.48 ? 439 ASN B O 1 ATOM 6444 C CB . ASN B 1 441 ? 204.646 40.498 32.300 1.00 63.26 ? 439 ASN B CB 1 ATOM 6445 C CG . ASN B 1 441 ? 204.145 39.280 31.560 1.00 70.97 ? 439 ASN B CG 1 ATOM 6446 O OD1 . ASN B 1 441 ? 204.354 38.127 31.957 1.00 56.28 ? 439 ASN B OD1 1 ATOM 6447 N ND2 . ASN B 1 441 ? 203.446 39.521 30.473 1.00 64.98 ? 439 ASN B ND2 1 ATOM 6448 N N . GLU B 1 442 ? 201.801 41.815 34.296 1.00 52.30 ? 440 GLU B N 1 ATOM 6449 C CA . GLU B 1 442 ? 200.363 41.975 34.446 1.00 49.78 ? 440 GLU B CA 1 ATOM 6450 C C . GLU B 1 442 ? 199.753 43.195 33.797 1.00 47.16 ? 440 GLU B C 1 ATOM 6451 O O . GLU B 1 442 ? 200.450 44.075 33.275 1.00 45.39 ? 440 GLU B O 1 ATOM 6452 C CB . GLU B 1 442 ? 200.008 41.970 35.936 1.00 51.44 ? 440 GLU B CB 1 ATOM 6453 C CG . GLU B 1 442 ? 200.050 40.587 36.558 1.00 66.23 ? 440 GLU B CG 1 ATOM 6454 C CD . GLU B 1 442 ? 200.113 40.596 38.069 1.00 89.75 ? 440 GLU B CD 1 ATOM 6455 O OE1 . GLU B 1 442 ? 201.062 41.202 38.624 1.00 74.90 ? 440 GLU B OE1 1 ATOM 6456 O OE2 . GLU B 1 442 ? 199.213 39.992 38.698 1.00 85.91 ? 440 GLU B OE2 1 ATOM 6457 N N . VAL B 1 443 ? 198.411 43.234 33.851 1.00 39.66 ? 441 VAL B N 1 ATOM 6458 C CA . VAL B 1 443 ? 197.622 44.332 33.326 1.00 36.72 ? 441 VAL B CA 1 ATOM 6459 C C . VAL B 1 443 ? 197.053 45.034 34.534 1.00 36.61 ? 441 VAL B C 1 ATOM 6460 O O . VAL B 1 443 ? 196.291 44.438 35.305 1.00 34.76 ? 441 VAL B O 1 ATOM 6461 C CB . VAL B 1 443 ? 196.560 43.920 32.266 1.00 38.36 ? 441 VAL B CB 1 ATOM 6462 C CG1 . VAL B 1 443 ? 195.807 45.143 31.756 1.00 37.76 ? 441 VAL B CG1 1 ATOM 6463 C CG2 . VAL B 1 443 ? 197.207 43.178 31.106 1.00 37.12 ? 441 VAL B CG2 1 ATOM 6464 N N . ARG B 1 444 ? 197.545 46.264 34.740 1.00 31.51 ? 442 ARG B N 1 ATOM 6465 C CA . ARG B 1 444 ? 197.204 47.193 35.805 1.00 31.50 ? 442 ARG B CA 1 ATOM 6466 C C . ARG B 1 444 ? 197.514 48.665 35.415 1.00 33.25 ? 442 ARG B C 1 ATOM 6467 O O . ARG B 1 444 ? 198.347 48.933 34.541 1.00 32.07 ? 442 ARG B O 1 ATOM 6468 C CB . ARG B 1 444 ? 197.897 46.802 37.138 1.00 33.62 ? 442 ARG B CB 1 ATOM 6469 C CG . ARG B 1 444 ? 199.429 46.719 37.110 1.00 38.89 ? 442 ARG B CG 1 ATOM 6470 C CD . ARG B 1 444 ? 200.041 47.267 38.398 1.00 60.31 ? 442 ARG B CD 1 ATOM 6471 N NE . ARG B 1 444 ? 199.692 46.493 39.591 1.00 67.59 ? 442 ARG B NE 1 ATOM 6472 N N . PHE B 1 445 ? 196.862 49.604 36.095 1.00 27.91 ? 443 PHE B N 1 ATOM 6473 C CA . PHE B 1 445 ? 197.064 51.027 35.848 1.00 26.77 ? 443 PHE B CA 1 ATOM 6474 C C . PHE B 1 445 ? 197.694 51.693 37.076 1.00 33.34 ? 443 PHE B C 1 ATOM 6475 O O . PHE B 1 445 ? 197.382 51.346 38.220 1.00 32.59 ? 443 PHE B O 1 ATOM 6476 C CB . PHE B 1 445 ? 195.736 51.733 35.440 1.00 26.85 ? 443 PHE B CB 1 ATOM 6477 C CG . PHE B 1 445 ? 194.997 51.027 34.337 1.00 27.77 ? 443 PHE B CG 1 ATOM 6478 C CD1 . PHE B 1 445 ? 195.372 51.194 33.003 1.00 31.01 ? 443 PHE B CD1 1 ATOM 6479 C CD2 . PHE B 1 445 ? 193.963 50.138 34.624 1.00 29.11 ? 443 PHE B CD2 1 ATOM 6480 C CE1 . PHE B 1 445 ? 194.721 50.487 31.977 1.00 30.46 ? 443 PHE B CE1 1 ATOM 6481 C CE2 . PHE B 1 445 ? 193.287 49.463 33.588 1.00 30.33 ? 443 PHE B CE2 1 ATOM 6482 C CZ . PHE B 1 445 ? 193.689 49.623 32.278 1.00 27.60 ? 443 PHE B CZ 1 ATOM 6483 N N . ASP B 1 446 ? 198.577 52.661 36.832 1.00 31.17 ? 444 ASP B N 1 ATOM 6484 C CA . ASP B 1 446 ? 199.199 53.417 37.906 1.00 30.62 ? 444 ASP B CA 1 ATOM 6485 C C . ASP B 1 446 ? 198.173 54.457 38.402 1.00 36.71 ? 444 ASP B C 1 ATOM 6486 O O . ASP B 1 446 ? 197.045 54.479 37.896 1.00 33.45 ? 444 ASP B O 1 ATOM 6487 C CB . ASP B 1 446 ? 200.571 54.007 37.466 1.00 31.18 ? 444 ASP B CB 1 ATOM 6488 C CG . ASP B 1 446 ? 200.548 55.141 36.462 1.00 46.34 ? 444 ASP B CG 1 ATOM 6489 O OD1 . ASP B 1 446 ? 199.495 55.803 36.328 1.00 48.30 ? 444 ASP B OD1 1 ATOM 6490 O OD2 . ASP B 1 446 ? 201.613 55.435 35.879 1.00 57.01 ? 444 ASP B OD2 1 ATOM 6491 N N . ARG B 1 447 ? 198.552 55.299 39.388 1.00 38.98 ? 445 ARG B N 1 ATOM 6492 C CA . ARG B 1 447 ? 197.664 56.324 39.964 1.00 41.24 ? 445 ARG B CA 1 ATOM 6493 C C . ARG B 1 447 ? 197.054 57.266 38.887 1.00 48.82 ? 445 ARG B C 1 ATOM 6494 O O . ARG B 1 447 ? 195.921 57.726 39.053 1.00 48.37 ? 445 ARG B O 1 ATOM 6495 C CB . ARG B 1 447 ? 198.383 57.112 41.070 1.00 40.88 ? 445 ARG B CB 1 ATOM 6496 N N . PHE B 1 448 ? 197.779 57.492 37.767 1.00 46.16 ? 446 PHE B N 1 ATOM 6497 C CA . PHE B 1 448 ? 197.279 58.328 36.672 1.00 46.56 ? 446 PHE B CA 1 ATOM 6498 C C . PHE B 1 448 ? 196.636 57.487 35.533 1.00 48.28 ? 446 PHE B C 1 ATOM 6499 O O . PHE B 1 448 ? 196.445 57.995 34.427 1.00 47.48 ? 446 PHE B O 1 ATOM 6500 C CB . PHE B 1 448 ? 198.375 59.256 36.111 1.00 49.11 ? 446 PHE B CB 1 ATOM 6501 C CG . PHE B 1 448 ? 199.439 59.756 37.061 1.00 51.69 ? 446 PHE B CG 1 ATOM 6502 C CD1 . PHE B 1 448 ? 199.161 60.770 37.974 1.00 54.93 ? 446 PHE B CD1 1 ATOM 6503 C CD2 . PHE B 1 448 ? 200.743 59.271 36.988 1.00 54.45 ? 446 PHE B CD2 1 ATOM 6504 C CE1 . PHE B 1 448 ? 200.158 61.256 38.831 1.00 55.44 ? 446 PHE B CE1 1 ATOM 6505 C CE2 . PHE B 1 448 ? 201.743 59.769 37.838 1.00 57.15 ? 446 PHE B CE2 1 ATOM 6506 C CZ . PHE B 1 448 ? 201.443 60.761 38.750 1.00 54.59 ? 446 PHE B CZ 1 ATOM 6507 N N . GLY B 1 449 ? 196.298 56.229 35.821 1.00 42.55 ? 447 GLY B N 1 ATOM 6508 C CA . GLY B 1 449 ? 195.678 55.329 34.850 1.00 41.02 ? 447 GLY B CA 1 ATOM 6509 C C . GLY B 1 449 ? 196.528 54.981 33.637 1.00 41.95 ? 447 GLY B C 1 ATOM 6510 O O . GLY B 1 449 ? 195.986 54.709 32.563 1.00 40.71 ? 447 GLY B O 1 ATOM 6511 N N . ASP B 1 450 ? 197.867 54.982 33.803 1.00 37.56 ? 448 ASP B N 1 ATOM 6512 C CA . ASP B 1 450 ? 198.844 54.712 32.747 1.00 37.48 ? 448 ASP B CA 1 ATOM 6513 C C . ASP B 1 450 ? 199.392 53.295 32.848 1.00 42.64 ? 448 ASP B C 1 ATOM 6514 O O . ASP B 1 450 ? 199.115 52.614 33.831 1.00 42.20 ? 448 ASP B O 1 ATOM 6515 C CB . ASP B 1 450 ? 200.022 55.711 32.846 1.00 39.04 ? 448 ASP B CB 1 ATOM 6516 C CG . ASP B 1 450 ? 199.680 57.187 32.768 1.00 46.19 ? 448 ASP B CG 1 ATOM 6517 O OD1 . ASP B 1 450 ? 198.810 57.554 31.951 1.00 43.01 ? 448 ASP B OD1 1 ATOM 6518 O OD2 . ASP B 1 450 ? 200.346 57.988 33.463 1.00 55.26 ? 448 ASP B OD2 1 ATOM 6519 N N . GLY B 1 451 ? 200.187 52.895 31.843 1.00 40.62 ? 449 GLY B N 1 ATOM 6520 C CA . GLY B 1 451 ? 200.895 51.623 31.763 1.00 41.68 ? 449 GLY B CA 1 ATOM 6521 C C . GLY B 1 451 ? 202.374 51.746 32.108 1.00 51.03 ? 449 GLY B C 1 ATOM 6522 O O . GLY B 1 451 ? 202.864 52.853 32.354 1.00 49.82 ? 449 GLY B O 1 ATOM 6523 N N . ILE B 1 452 ? 203.105 50.603 32.141 1.00 53.26 ? 450 ILE B N 1 ATOM 6524 C CA . ILE B 1 452 ? 204.546 50.546 32.502 1.00 55.60 ? 450 ILE B CA 1 ATOM 6525 C C . ILE B 1 452 ? 205.507 50.874 31.302 1.00 60.48 ? 450 ILE B C 1 ATOM 6526 O O . ILE B 1 452 ? 205.477 50.190 30.264 1.00 60.46 ? 450 ILE B O 1 ATOM 6527 C CB . ILE B 1 452 ? 204.904 49.189 33.198 1.00 59.62 ? 450 ILE B CB 1 ATOM 6528 C CG1 . ILE B 1 452 ? 203.967 48.928 34.397 1.00 61.54 ? 450 ILE B CG1 1 ATOM 6529 C CG2 . ILE B 1 452 ? 206.355 49.169 33.676 1.00 59.98 ? 450 ILE B CG2 1 ATOM 6530 C CD1 . ILE B 1 452 ? 203.434 47.460 34.540 1.00 74.54 ? 450 ILE B CD1 1 ATOM 6531 N N . GLY B 1 453 ? 206.380 51.870 31.515 1.00 55.82 ? 451 GLY B N 1 ATOM 6532 C CA . GLY B 1 453 ? 207.359 52.344 30.533 1.00 55.18 ? 451 GLY B CA 1 ATOM 6533 C C . GLY B 1 453 ? 208.450 51.386 30.066 1.00 57.69 ? 451 GLY B C 1 ATOM 6534 O O . GLY B 1 453 ? 209.616 51.568 30.442 1.00 57.69 ? 451 GLY B O 1 ATOM 6535 N N . ARG B 1 454 ? 208.095 50.389 29.196 1.00 51.77 ? 452 ARG B N 1 ATOM 6536 C CA . ARG B 1 454 ? 209.029 49.423 28.576 1.00 50.32 ? 452 ARG B CA 1 ATOM 6537 C C . ARG B 1 454 ? 209.079 49.600 27.024 1.00 52.23 ? 452 ARG B C 1 ATOM 6538 O O . ARG B 1 454 ? 208.069 49.417 26.347 1.00 51.59 ? 452 ARG B O 1 ATOM 6539 C CB . ARG B 1 454 ? 208.696 47.977 28.984 1.00 47.52 ? 452 ARG B CB 1 ATOM 6540 N N . TYR B 1 455 ? 210.252 49.956 26.477 1.00 47.49 ? 453 TYR B N 1 ATOM 6541 C CA . TYR B 1 455 ? 210.443 50.220 25.046 1.00 47.41 ? 453 TYR B CA 1 ATOM 6542 C C . TYR B 1 455 ? 211.558 49.407 24.407 1.00 50.92 ? 453 TYR B C 1 ATOM 6543 O O . TYR B 1 455 ? 212.645 49.336 24.967 1.00 51.16 ? 453 TYR B O 1 ATOM 6544 C CB . TYR B 1 455 ? 210.803 51.709 24.837 1.00 49.03 ? 453 TYR B CB 1 ATOM 6545 C CG . TYR B 1 455 ? 209.831 52.675 25.472 1.00 51.64 ? 453 TYR B CG 1 ATOM 6546 C CD1 . TYR B 1 455 ? 209.985 53.081 26.793 1.00 53.61 ? 453 TYR B CD1 1 ATOM 6547 C CD2 . TYR B 1 455 ? 208.735 53.158 24.763 1.00 52.58 ? 453 TYR B CD2 1 ATOM 6548 C CE1 . TYR B 1 455 ? 209.062 53.928 27.400 1.00 55.07 ? 453 TYR B CE1 1 ATOM 6549 C CE2 . TYR B 1 455 ? 207.824 54.031 25.350 1.00 53.56 ? 453 TYR B CE2 1 ATOM 6550 C CZ . TYR B 1 455 ? 207.988 54.408 26.671 1.00 60.25 ? 453 TYR B CZ 1 ATOM 6551 O OH . TYR B 1 455 ? 207.090 55.263 27.248 1.00 60.95 ? 453 TYR B OH 1 ATOM 6552 N N . ASN B 1 456 ? 211.336 48.884 23.197 1.00 45.82 ? 454 ASN B N 1 ATOM 6553 C CA . ASN B 1 456 ? 212.383 48.209 22.440 1.00 45.55 ? 454 ASN B CA 1 ATOM 6554 C C . ASN B 1 456 ? 213.041 49.210 21.458 1.00 50.66 ? 454 ASN B C 1 ATOM 6555 O O . ASN B 1 456 ? 212.338 49.989 20.808 1.00 51.37 ? 454 ASN B O 1 ATOM 6556 C CB . ASN B 1 456 ? 211.836 46.980 21.716 1.00 44.42 ? 454 ASN B CB 1 ATOM 6557 C CG . ASN B 1 456 ? 211.494 45.807 22.614 1.00 61.53 ? 454 ASN B CG 1 ATOM 6558 O OD1 . ASN B 1 456 ? 211.939 45.701 23.769 1.00 56.41 ? 454 ASN B OD1 1 ATOM 6559 N ND2 . ASN B 1 456 ? 210.733 44.863 22.077 1.00 49.87 ? 454 ASN B ND2 1 ATOM 6560 N N . ILE B 1 457 ? 214.346 49.172 21.342 1.00 46.26 ? 455 ILE B N 1 ATOM 6561 C CA . ILE B 1 457 ? 215.017 50.065 20.446 1.00 45.62 ? 455 ILE B CA 1 ATOM 6562 C C . ILE B 1 457 ? 215.462 49.348 19.195 1.00 49.49 ? 455 ILE B C 1 ATOM 6563 O O . ILE B 1 457 ? 215.968 48.270 19.238 1.00 48.80 ? 455 ILE B O 1 ATOM 6564 C CB . ILE B 1 457 ? 216.171 50.784 21.142 1.00 48.32 ? 455 ILE B CB 1 ATOM 6565 C CG1 . ILE B 1 457 ? 215.619 51.812 22.098 1.00 47.71 ? 455 ILE B CG1 1 ATOM 6566 C CG2 . ILE B 1 457 ? 217.047 51.513 20.154 1.00 49.71 ? 455 ILE B CG2 1 ATOM 6567 C CD1 . ILE B 1 457 ? 216.006 51.595 23.521 1.00 46.94 ? 455 ILE B CD1 1 ATOM 6568 N N . PHE B 1 458 ? 215.237 49.983 18.070 1.00 46.78 ? 456 PHE B N 1 ATOM 6569 C CA . PHE B 1 458 ? 215.499 49.363 16.775 1.00 47.05 ? 456 PHE B CA 1 ATOM 6570 C C . PHE B 1 458 ? 216.385 50.217 15.928 1.00 54.10 ? 456 PHE B C 1 ATOM 6571 O O . PHE B 1 458 ? 216.457 51.426 16.141 1.00 53.92 ? 456 PHE B O 1 ATOM 6572 C CB . PHE B 1 458 ? 214.187 49.093 16.019 1.00 48.36 ? 456 PHE B CB 1 ATOM 6573 C CG . PHE B 1 458 ? 213.255 48.152 16.740 1.00 49.47 ? 456 PHE B CG 1 ATOM 6574 C CD1 . PHE B 1 458 ? 212.325 48.634 17.651 1.00 52.22 ? 456 PHE B CD1 1 ATOM 6575 C CD2 . PHE B 1 458 ? 213.326 46.783 16.529 1.00 51.28 ? 456 PHE B CD2 1 ATOM 6576 C CE1 . PHE B 1 458 ? 211.486 47.761 18.340 1.00 53.34 ? 456 PHE B CE1 1 ATOM 6577 C CE2 . PHE B 1 458 ? 212.485 45.910 17.219 1.00 54.14 ? 456 PHE B CE2 1 ATOM 6578 C CZ . PHE B 1 458 ? 211.565 46.407 18.113 1.00 52.57 ? 456 PHE B CZ 1 ATOM 6579 N N . THR B 1 459 ? 217.069 49.583 14.969 1.00 53.83 ? 457 THR B N 1 ATOM 6580 C CA . THR B 1 459 ? 217.925 50.257 13.997 1.00 54.91 ? 457 THR B CA 1 ATOM 6581 C C . THR B 1 459 ? 217.532 49.774 12.608 1.00 60.11 ? 457 THR B C 1 ATOM 6582 O O . THR B 1 459 ? 217.262 48.585 12.424 1.00 59.51 ? 457 THR B O 1 ATOM 6583 C CB . THR B 1 459 ? 219.421 50.161 14.371 1.00 65.25 ? 457 THR B CB 1 ATOM 6584 O OG1 . THR B 1 459 ? 220.015 51.457 14.252 1.00 63.89 ? 457 THR B OG1 1 ATOM 6585 C CG2 . THR B 1 459 ? 220.195 49.142 13.543 1.00 65.51 ? 457 THR B CG2 1 ATOM 6586 N N . TYR B 1 460 ? 217.404 50.705 11.665 1.00 59.09 ? 458 TYR B N 1 ATOM 6587 C CA . TYR B 1 460 ? 217.059 50.342 10.297 1.00 61.03 ? 458 TYR B CA 1 ATOM 6588 C C . TYR B 1 460 ? 218.365 50.125 9.542 1.00 71.80 ? 458 TYR B C 1 ATOM 6589 O O . TYR B 1 460 ? 219.223 51.016 9.513 1.00 72.24 ? 458 TYR B O 1 ATOM 6590 C CB . TYR B 1 460 ? 216.199 51.420 9.629 1.00 61.21 ? 458 TYR B CB 1 ATOM 6591 C CG . TYR B 1 460 ? 215.429 50.924 8.426 1.00 60.73 ? 458 TYR B CG 1 ATOM 6592 C CD1 . TYR B 1 460 ? 214.411 49.983 8.565 1.00 62.60 ? 458 TYR B CD1 1 ATOM 6593 C CD2 . TYR B 1 460 ? 215.675 51.437 7.157 1.00 60.48 ? 458 TYR B CD2 1 ATOM 6594 C CE1 . TYR B 1 460 ? 213.686 49.533 7.464 1.00 62.25 ? 458 TYR B CE1 1 ATOM 6595 C CE2 . TYR B 1 460 ? 214.945 51.006 6.050 1.00 61.14 ? 458 TYR B CE2 1 ATOM 6596 C CZ . TYR B 1 460 ? 213.951 50.052 6.209 1.00 67.26 ? 458 TYR B CZ 1 ATOM 6597 O OH . TYR B 1 460 ? 213.222 49.615 5.129 1.00 67.34 ? 458 TYR B OH 1 ATOM 6598 N N . LEU B 1 461 ? 218.542 48.916 8.995 1.00 72.23 ? 459 LEU B N 1 ATOM 6599 C CA . LEU B 1 461 ? 219.770 48.524 8.294 1.00 73.98 ? 459 LEU B CA 1 ATOM 6600 C C . LEU B 1 461 ? 219.524 47.607 7.086 1.00 83.07 ? 459 LEU B C 1 ATOM 6601 O O . LEU B 1 461 ? 218.417 47.071 6.917 1.00 83.05 ? 459 LEU B O 1 ATOM 6602 C CB . LEU B 1 461 ? 220.756 47.845 9.288 1.00 73.80 ? 459 LEU B CB 1 ATOM 6603 C CG . LEU B 1 461 ? 220.248 46.652 10.142 1.00 78.32 ? 459 LEU B CG 1 ATOM 6604 C CD1 . LEU B 1 461 ? 220.178 45.369 9.347 1.00 77.89 ? 459 LEU B CD1 1 ATOM 6605 C CD2 . LEU B 1 461 ? 221.169 46.399 11.308 1.00 81.87 ? 459 LEU B CD2 1 ATOM 6606 N N . ARG B 1 462 ? 220.589 47.389 6.283 1.00 82.36 ? 460 ARG B N 1 ATOM 6607 C CA . ARG B 1 462 ? 220.583 46.451 5.163 1.00 83.23 ? 460 ARG B CA 1 ATOM 6608 C C . ARG B 1 462 ? 221.534 45.280 5.503 1.00 89.62 ? 460 ARG B C 1 ATOM 6609 O O . ARG B 1 462 ? 222.425 45.444 6.352 1.00 88.50 ? 460 ARG B O 1 ATOM 6610 C CB . ARG B 1 462 ? 220.952 47.148 3.843 1.00 83.76 ? 460 ARG B CB 1 ATOM 6611 N N . ALA B 1 463 ? 221.321 44.092 4.888 1.00 88.85 ? 461 ALA B N 1 ATOM 6612 C CA . ALA B 1 463 ? 222.155 42.907 5.160 1.00 89.57 ? 461 ALA B CA 1 ATOM 6613 C C . ALA B 1 463 ? 222.595 42.113 3.882 1.00 94.61 ? 461 ALA B C 1 ATOM 6614 O O . ALA B 1 463 ? 223.642 42.431 3.300 1.00 93.78 ? 461 ALA B O 1 ATOM 6615 C CB . ALA B 1 463 ? 221.466 41.995 6.176 1.00 90.21 ? 461 ALA B CB 1 ATOM 6616 N N . GLY B 1 464 ? 221.816 41.092 3.492 1.00 91.45 ? 462 GLY B N 1 ATOM 6617 C CA . GLY B 1 464 ? 222.088 40.247 2.333 1.00 110.53 ? 462 GLY B CA 1 ATOM 6618 C C . GLY B 1 464 ? 221.080 40.431 1.217 1.00 121.14 ? 462 GLY B C 1 ATOM 6619 O O . GLY B 1 464 ? 220.870 41.545 0.733 1.00 75.18 ? 462 GLY B O 1 ATOM 6620 N N . GLY B 1 466 ? 219.465 47.258 -0.168 1.00 78.92 ? 464 GLY B N 1 ATOM 6621 C CA . GLY B 1 466 ? 218.746 45.989 -0.159 1.00 79.17 ? 464 GLY B CA 1 ATOM 6622 C C . GLY B 1 466 ? 219.524 44.810 0.414 1.00 84.56 ? 464 GLY B C 1 ATOM 6623 O O . GLY B 1 466 ? 220.711 44.651 0.112 1.00 84.70 ? 464 GLY B O 1 ATOM 6624 N N . ARG B 1 467 ? 218.878 43.928 1.222 1.00 81.07 ? 465 ARG B N 1 ATOM 6625 C CA . ARG B 1 467 ? 217.483 44.009 1.681 1.00 80.34 ? 465 ARG B CA 1 ATOM 6626 C C . ARG B 1 467 ? 217.442 44.756 3.033 1.00 82.72 ? 465 ARG B C 1 ATOM 6627 O O . ARG B 1 467 ? 218.407 44.679 3.801 1.00 83.36 ? 465 ARG B O 1 ATOM 6628 C CB . ARG B 1 467 ? 216.863 42.603 1.794 1.00 79.86 ? 465 ARG B CB 1 ATOM 6629 N N . TYR B 1 468 ? 216.347 45.489 3.317 1.00 76.05 ? 466 TYR B N 1 ATOM 6630 C CA . TYR B 1 468 ? 216.236 46.272 4.552 1.00 73.85 ? 466 TYR B CA 1 ATOM 6631 C C . TYR B 1 468 ? 215.404 45.630 5.673 1.00 73.51 ? 466 TYR B C 1 ATOM 6632 O O . TYR B 1 468 ? 214.447 44.892 5.405 1.00 72.79 ? 466 TYR B O 1 ATOM 6633 C CB . TYR B 1 468 ? 215.714 47.670 4.243 1.00 74.51 ? 466 TYR B CB 1 ATOM 6634 C CG . TYR B 1 468 ? 216.731 48.571 3.583 1.00 75.59 ? 466 TYR B CG 1 ATOM 6635 C CD1 . TYR B 1 468 ? 217.623 49.324 4.342 1.00 77.02 ? 466 TYR B CD1 1 ATOM 6636 C CD2 . TYR B 1 468 ? 216.783 48.699 2.199 1.00 76.43 ? 466 TYR B CD2 1 ATOM 6637 C CE1 . TYR B 1 468 ? 218.545 50.177 3.740 1.00 77.38 ? 466 TYR B CE1 1 ATOM 6638 C CE2 . TYR B 1 468 ? 217.692 49.560 1.585 1.00 77.42 ? 466 TYR B CE2 1 ATOM 6639 C CZ . TYR B 1 468 ? 218.576 50.294 2.359 1.00 84.65 ? 466 TYR B CZ 1 ATOM 6640 O OH . TYR B 1 468 ? 219.482 51.138 1.755 1.00 85.80 ? 466 TYR B OH 1 ATOM 6641 N N . ARG B 1 469 ? 215.777 45.935 6.939 1.00 66.89 ? 467 ARG B N 1 ATOM 6642 C CA . ARG B 1 469 ? 215.092 45.432 8.143 1.00 65.11 ? 467 ARG B CA 1 ATOM 6643 C C . ARG B 1 469 ? 215.272 46.322 9.403 1.00 65.02 ? 467 ARG B C 1 ATOM 6644 O O . ARG B 1 469 ? 216.179 47.158 9.469 1.00 64.01 ? 467 ARG B O 1 ATOM 6645 C CB . ARG B 1 469 ? 215.509 43.968 8.459 1.00 64.11 ? 467 ARG B CB 1 ATOM 6646 C CG . ARG B 1 469 ? 216.949 43.822 8.974 1.00 71.46 ? 467 ARG B CG 1 ATOM 6647 C CD . ARG B 1 469 ? 217.155 42.628 9.882 1.00 76.48 ? 467 ARG B CD 1 ATOM 6648 N NE . ARG B 1 469 ? 218.486 42.635 10.483 1.00 79.98 ? 467 ARG B NE 1 ATOM 6649 N N . TYR B 1 470 ? 214.415 46.080 10.412 1.00 59.03 ? 468 TYR B N 1 ATOM 6650 C CA . TYR B 1 470 ? 214.450 46.704 11.729 1.00 57.54 ? 468 TYR B CA 1 ATOM 6651 C C . TYR B 1 470 ? 215.115 45.711 12.674 1.00 60.69 ? 468 TYR B C 1 ATOM 6652 O O . TYR B 1 470 ? 214.609 44.599 12.856 1.00 59.97 ? 468 TYR B O 1 ATOM 6653 C CB . TYR B 1 470 ? 213.034 47.015 12.219 1.00 57.85 ? 468 TYR B CB 1 ATOM 6654 C CG . TYR B 1 470 ? 212.430 48.259 11.615 1.00 57.72 ? 468 TYR B CG 1 ATOM 6655 C CD1 . TYR B 1 470 ? 212.793 49.526 12.070 1.00 58.52 ? 468 TYR B CD1 1 ATOM 6656 C CD2 . TYR B 1 470 ? 211.456 48.173 10.628 1.00 58.24 ? 468 TYR B CD2 1 ATOM 6657 C CE1 . TYR B 1 470 ? 212.221 50.676 11.536 1.00 57.19 ? 468 TYR B CE1 1 ATOM 6658 C CE2 . TYR B 1 470 ? 210.877 49.317 10.085 1.00 58.95 ? 468 TYR B CE2 1 ATOM 6659 C CZ . TYR B 1 470 ? 211.255 50.565 10.551 1.00 61.47 ? 468 TYR B CZ 1 ATOM 6660 O OH . TYR B 1 470 ? 210.667 51.683 10.028 1.00 57.79 ? 468 TYR B OH 1 ATOM 6661 N N . GLN B 1 471 ? 216.254 46.100 13.259 1.00 56.72 ? 469 GLN B N 1 ATOM 6662 C CA . GLN B 1 471 ? 217.010 45.223 14.139 1.00 56.39 ? 469 GLN B CA 1 ATOM 6663 C C . GLN B 1 471 ? 216.908 45.681 15.591 1.00 60.48 ? 469 GLN B C 1 ATOM 6664 O O . GLN B 1 471 ? 217.339 46.795 15.905 1.00 60.59 ? 469 GLN B O 1 ATOM 6665 C CB . GLN B 1 471 ? 218.491 45.126 13.662 1.00 57.72 ? 469 GLN B CB 1 ATOM 6666 C CG . GLN B 1 471 ? 219.401 44.115 14.413 1.00 65.00 ? 469 GLN B CG 1 ATOM 6667 C CD . GLN B 1 471 ? 218.915 42.676 14.388 1.00 83.14 ? 469 GLN B CD 1 ATOM 6668 O OE1 . GLN B 1 471 ? 218.744 42.053 13.327 1.00 77.83 ? 469 GLN B OE1 1 ATOM 6669 N NE2 . GLN B 1 471 ? 218.686 42.115 15.571 1.00 74.33 ? 469 GLN B NE2 1 ATOM 6670 N N . LYS B 1 472 ? 216.365 44.809 16.477 1.00 55.77 ? 470 LYS B N 1 ATOM 6671 C CA . LYS B 1 472 ? 216.252 45.096 17.900 1.00 55.76 ? 470 LYS B CA 1 ATOM 6672 C C . LYS B 1 472 ? 217.659 45.205 18.478 1.00 63.12 ? 470 LYS B C 1 ATOM 6673 O O . LYS B 1 472 ? 218.283 44.187 18.781 1.00 64.76 ? 470 LYS B O 1 ATOM 6674 C CB . LYS B 1 472 ? 215.393 44.041 18.626 1.00 57.02 ? 470 LYS B CB 1 ATOM 6675 C CG . LYS B 1 472 ? 215.111 44.393 20.093 1.00 57.26 ? 470 LYS B CG 1 ATOM 6676 C CD . LYS B 1 472 ? 214.211 43.366 20.745 1.00 61.68 ? 470 LYS B CD 1 ATOM 6677 C CE . LYS B 1 472 ? 214.194 43.494 22.242 1.00 69.56 ? 470 LYS B CE 1 ATOM 6678 N NZ . LYS B 1 472 ? 213.194 42.575 22.841 1.00 80.21 ? 470 LYS B NZ 1 ATOM 6679 N N . VAL B 1 473 ? 218.166 46.453 18.575 1.00 59.88 ? 471 VAL B N 1 ATOM 6680 C CA . VAL B 1 473 ? 219.517 46.808 19.033 1.00 59.34 ? 471 VAL B CA 1 ATOM 6681 C C . VAL B 1 473 ? 219.613 47.165 20.540 1.00 64.01 ? 471 VAL B C 1 ATOM 6682 O O . VAL B 1 473 ? 220.711 47.435 21.027 1.00 64.68 ? 471 VAL B O 1 ATOM 6683 C CB . VAL B 1 473 ? 220.137 47.924 18.150 1.00 63.32 ? 471 VAL B CB 1 ATOM 6684 C CG1 . VAL B 1 473 ? 220.518 47.385 16.776 1.00 63.38 ? 471 VAL B CG1 1 ATOM 6685 C CG2 . VAL B 1 473 ? 219.212 49.136 18.019 1.00 63.02 ? 471 VAL B CG2 1 ATOM 6686 N N . GLY B 1 474 ? 218.491 47.145 21.257 1.00 59.96 ? 472 GLY B N 1 ATOM 6687 C CA . GLY B 1 474 ? 218.453 47.460 22.684 1.00 59.11 ? 472 GLY B CA 1 ATOM 6688 C C . GLY B 1 474 ? 217.062 47.611 23.259 1.00 62.14 ? 472 GLY B C 1 ATOM 6689 O O . GLY B 1 474 ? 216.073 47.266 22.605 1.00 62.38 ? 472 GLY B O 1 ATOM 6690 N N . TYR B 1 475 ? 216.982 48.091 24.504 1.00 58.33 ? 473 TYR B N 1 ATOM 6691 C CA . TYR B 1 475 ? 215.720 48.330 25.202 1.00 58.73 ? 473 TYR B CA 1 ATOM 6692 C C . TYR B 1 475 ? 215.844 49.407 26.293 1.00 62.20 ? 473 TYR B C 1 ATOM 6693 O O . TYR B 1 475 ? 216.933 49.886 26.581 1.00 60.86 ? 473 TYR B O 1 ATOM 6694 C CB . TYR B 1 475 ? 215.071 47.036 25.739 1.00 60.97 ? 473 TYR B CB 1 ATOM 6695 C CG . TYR B 1 475 ? 215.853 46.335 26.825 1.00 65.15 ? 473 TYR B CG 1 ATOM 6696 C CD1 . TYR B 1 475 ? 215.661 46.653 28.167 1.00 67.63 ? 473 TYR B CD1 1 ATOM 6697 C CD2 . TYR B 1 475 ? 216.732 45.301 26.520 1.00 66.82 ? 473 TYR B CD2 1 ATOM 6698 C CE1 . TYR B 1 475 ? 216.365 45.990 29.176 1.00 69.50 ? 473 TYR B CE1 1 ATOM 6699 C CE2 . TYR B 1 475 ? 217.441 44.630 27.520 1.00 68.03 ? 473 TYR B CE2 1 ATOM 6700 C CZ . TYR B 1 475 ? 217.253 44.976 28.847 1.00 76.05 ? 473 TYR B CZ 1 ATOM 6701 O OH . TYR B 1 475 ? 217.967 44.327 29.823 1.00 77.11 ? 473 TYR B OH 1 ATOM 6702 N N . TRP B 1 476 ? 214.700 49.832 26.836 1.00 59.88 ? 474 TRP B N 1 ATOM 6703 C CA . TRP B 1 476 ? 214.586 50.831 27.887 1.00 59.69 ? 474 TRP B CA 1 ATOM 6704 C C . TRP B 1 476 ? 213.464 50.394 28.784 1.00 64.06 ? 474 TRP B C 1 ATOM 6705 O O . TRP B 1 476 ? 212.316 50.301 28.359 1.00 63.65 ? 474 TRP B O 1 ATOM 6706 C CB . TRP B 1 476 ? 214.323 52.239 27.326 1.00 58.41 ? 474 TRP B CB 1 ATOM 6707 C CG . TRP B 1 476 ? 214.647 53.330 28.306 1.00 59.45 ? 474 TRP B CG 1 ATOM 6708 C CD1 . TRP B 1 476 ? 215.765 54.115 28.314 1.00 62.37 ? 474 TRP B CD1 1 ATOM 6709 C CD2 . TRP B 1 476 ? 213.873 53.721 29.449 1.00 59.23 ? 474 TRP B CD2 1 ATOM 6710 N NE1 . TRP B 1 476 ? 215.735 54.972 29.389 1.00 61.75 ? 474 TRP B NE1 1 ATOM 6711 C CE2 . TRP B 1 476 ? 214.584 54.753 30.103 1.00 63.22 ? 474 TRP B CE2 1 ATOM 6712 C CE3 . TRP B 1 476 ? 212.652 53.292 29.995 1.00 60.65 ? 474 TRP B CE3 1 ATOM 6713 C CZ2 . TRP B 1 476 ? 214.113 55.363 31.272 1.00 62.56 ? 474 TRP B CZ2 1 ATOM 6714 C CZ3 . TRP B 1 476 ? 212.188 53.891 31.156 1.00 62.34 ? 474 TRP B CZ3 1 ATOM 6715 C CH2 . TRP B 1 476 ? 212.914 54.914 31.782 1.00 63.04 ? 474 TRP B CH2 1 ATOM 6716 N N . ALA B 1 477 ? 213.807 50.078 30.013 1.00 61.79 ? 475 ALA B N 1 ATOM 6717 C CA . ALA B 1 477 ? 212.888 49.624 31.039 1.00 62.48 ? 475 ALA B CA 1 ATOM 6718 C C . ALA B 1 477 ? 213.604 50.007 32.314 1.00 69.82 ? 475 ALA B C 1 ATOM 6719 O O . ALA B 1 477 ? 214.463 49.260 32.800 1.00 70.52 ? 475 ALA B O 1 ATOM 6720 C CB . ALA B 1 477 ? 212.701 48.113 30.941 1.00 63.05 ? 475 ALA B CB 1 ATOM 6721 N N . GLU B 1 478 ? 213.326 51.238 32.792 1.00 67.56 ? 476 GLU B N 1 ATOM 6722 C CA . GLU B 1 478 ? 213.980 51.856 33.948 1.00 67.65 ? 476 GLU B CA 1 ATOM 6723 C C . GLU B 1 478 ? 215.501 51.936 33.689 1.00 71.24 ? 476 GLU B C 1 ATOM 6724 O O . GLU B 1 478 ? 216.305 51.401 34.463 1.00 71.63 ? 476 GLU B O 1 ATOM 6725 C CB . GLU B 1 478 ? 213.617 51.147 35.282 1.00 69.09 ? 476 GLU B CB 1 ATOM 6726 C CG . GLU B 1 478 ? 212.330 51.647 35.933 1.00 82.24 ? 476 GLU B CG 1 ATOM 6727 C CD . GLU B 1 478 ? 212.194 53.145 36.181 1.00 106.70 ? 476 GLU B CD 1 ATOM 6728 O OE1 . GLU B 1 478 ? 211.091 53.685 35.932 1.00 97.14 ? 476 GLU B OE1 1 ATOM 6729 O OE2 . GLU B 1 478 ? 213.185 53.780 36.613 1.00 103.74 ? 476 GLU B OE2 1 ATOM 6730 N N . GLY B 1 479 ? 215.852 52.553 32.557 1.00 66.08 ? 477 GLY B N 1 ATOM 6731 C CA . GLY B 1 479 ? 217.227 52.730 32.101 1.00 65.41 ? 477 GLY B CA 1 ATOM 6732 C C . GLY B 1 479 ? 217.473 52.183 30.708 1.00 68.12 ? 477 GLY B C 1 ATOM 6733 O O . GLY B 1 479 ? 216.787 51.248 30.290 1.00 68.26 ? 477 GLY B O 1 ATOM 6734 N N . LEU B 1 480 ? 218.465 52.751 29.981 1.00 62.95 ? 478 LEU B N 1 ATOM 6735 C CA . LEU B 1 480 ? 218.800 52.326 28.618 1.00 62.75 ? 478 LEU B CA 1 ATOM 6736 C C . LEU B 1 480 ? 219.771 51.139 28.587 1.00 69.62 ? 478 LEU B C 1 ATOM 6737 O O . LEU B 1 480 ? 220.811 51.174 29.241 1.00 70.78 ? 478 LEU B O 1 ATOM 6738 C CB . LEU B 1 480 ? 219.312 53.529 27.806 1.00 62.39 ? 478 LEU B CB 1 ATOM 6739 C CG . LEU B 1 480 ? 219.903 53.310 26.404 1.00 66.12 ? 478 LEU B CG 1 ATOM 6740 C CD1 . LEU B 1 480 ? 218.857 52.902 25.409 1.00 65.27 ? 478 LEU B CD1 1 ATOM 6741 C CD2 . LEU B 1 480 ? 220.560 54.573 25.918 1.00 69.07 ? 478 LEU B CD2 1 ATOM 6742 N N . THR B 1 481 ? 219.430 50.089 27.825 1.00 66.86 ? 479 THR B N 1 ATOM 6743 C CA . THR B 1 481 ? 220.229 48.864 27.731 1.00 66.63 ? 479 THR B CA 1 ATOM 6744 C C . THR B 1 481 ? 220.390 48.419 26.273 1.00 72.48 ? 479 THR B C 1 ATOM 6745 O O . THR B 1 481 ? 219.863 47.374 25.888 1.00 71.94 ? 479 THR B O 1 ATOM 6746 C CB . THR B 1 481 ? 219.642 47.779 28.662 1.00 69.32 ? 479 THR B CB 1 ATOM 6747 O OG1 . THR B 1 481 ? 219.299 48.356 29.926 1.00 69.54 ? 479 THR B OG1 1 ATOM 6748 C CG2 . THR B 1 481 ? 220.577 46.617 28.876 1.00 66.20 ? 479 THR B CG2 1 ATOM 6749 N N . LEU B 1 482 ? 221.119 49.212 25.464 1.00 71.35 ? 480 LEU B N 1 ATOM 6750 C CA . LEU B 1 482 ? 221.398 48.879 24.060 1.00 72.83 ? 480 LEU B CA 1 ATOM 6751 C C . LEU B 1 482 ? 222.632 47.956 23.902 1.00 81.68 ? 480 LEU B C 1 ATOM 6752 O O . LEU B 1 482 ? 223.182 47.477 24.899 1.00 81.80 ? 480 LEU B O 1 ATOM 6753 C CB . LEU B 1 482 ? 221.486 50.115 23.122 1.00 72.63 ? 480 LEU B CB 1 ATOM 6754 C CG . LEU B 1 482 ? 222.566 51.173 23.358 1.00 76.85 ? 480 LEU B CG 1 ATOM 6755 C CD1 . LEU B 1 482 ? 223.899 50.742 22.806 1.00 77.11 ? 480 LEU B CD1 1 ATOM 6756 C CD2 . LEU B 1 482 ? 222.175 52.484 22.732 1.00 77.86 ? 480 LEU B CD2 1 ATOM 6757 N N . ASP B 1 483 ? 223.032 47.674 22.647 1.00 81.31 ? 481 ASP B N 1 ATOM 6758 C CA . ASP B 1 483 ? 224.173 46.816 22.333 1.00 82.68 ? 481 ASP B CA 1 ATOM 6759 C C . ASP B 1 483 ? 224.899 47.271 21.052 1.00 89.05 ? 481 ASP B C 1 ATOM 6760 O O . ASP B 1 483 ? 224.360 47.124 19.945 1.00 88.64 ? 481 ASP B O 1 ATOM 6761 C CB . ASP B 1 483 ? 223.747 45.335 22.273 1.00 84.86 ? 481 ASP B CB 1 ATOM 6762 C CG . ASP B 1 483 ? 224.712 44.443 21.524 1.00 97.62 ? 481 ASP B CG 1 ATOM 6763 O OD1 . ASP B 1 483 ? 225.785 44.123 22.086 1.00 99.42 ? 481 ASP B OD1 1 ATOM 6764 O OD2 . ASP B 1 483 ? 224.431 44.126 20.351 1.00 103.06 ? 481 ASP B OD2 1 ATOM 6765 N N . THR B 1 484 ? 226.137 47.806 21.223 1.00 86.89 ? 482 THR B N 1 ATOM 6766 C CA . THR B 1 484 ? 227.028 48.311 20.167 1.00 86.86 ? 482 THR B CA 1 ATOM 6767 C C . THR B 1 484 ? 227.318 47.285 19.053 1.00 91.64 ? 482 THR B C 1 ATOM 6768 O O . THR B 1 484 ? 227.516 47.674 17.899 1.00 91.13 ? 482 THR B O 1 ATOM 6769 C CB . THR B 1 484 ? 228.314 48.857 20.779 1.00 93.05 ? 482 THR B CB 1 ATOM 6770 N N . SER B 1 485 ? 227.335 45.983 19.400 1.00 88.93 ? 483 SER B N 1 ATOM 6771 C CA . SER B 1 485 ? 227.576 44.873 18.475 1.00 88.99 ? 483 SER B CA 1 ATOM 6772 C C . SER B 1 485 ? 226.568 44.825 17.305 1.00 94.53 ? 483 SER B C 1 ATOM 6773 O O . SER B 1 485 ? 226.977 44.669 16.149 1.00 93.54 ? 483 SER B O 1 ATOM 6774 C CB . SER B 1 485 ? 227.570 43.551 19.234 1.00 91.33 ? 483 SER B CB 1 ATOM 6775 O OG . SER B 1 485 ? 227.515 42.451 18.342 1.00 100.41 ? 483 SER B OG 1 ATOM 6776 N N . LEU B 1 486 ? 225.262 44.961 17.617 1.00 92.42 ? 484 LEU B N 1 ATOM 6777 C CA . LEU B 1 486 ? 224.175 44.897 16.642 1.00 92.35 ? 484 LEU B CA 1 ATOM 6778 C C . LEU B 1 486 ? 224.055 46.149 15.766 1.00 96.66 ? 484 LEU B C 1 ATOM 6779 O O . LEU B 1 486 ? 223.679 46.019 14.597 1.00 96.08 ? 484 LEU B O 1 ATOM 6780 C CB . LEU B 1 486 ? 222.849 44.553 17.322 1.00 92.41 ? 484 LEU B CB 1 ATOM 6781 C CG . LEU B 1 486 ? 222.642 43.069 17.621 1.00 97.20 ? 484 LEU B CG 1 ATOM 6782 C CD1 . LEU B 1 486 ? 221.712 42.872 18.806 1.00 97.32 ? 484 LEU B CD1 1 ATOM 6783 C CD2 . LEU B 1 486 ? 222.127 42.319 16.390 1.00 99.98 ? 484 LEU B CD2 1 ATOM 6784 N N . ILE B 1 487 ? 224.387 47.348 16.304 1.00 93.70 ? 485 ILE B N 1 ATOM 6785 C CA . ILE B 1 487 ? 224.381 48.584 15.506 1.00 93.80 ? 485 ILE B CA 1 ATOM 6786 C C . ILE B 1 487 ? 225.586 48.539 14.548 1.00 97.33 ? 485 ILE B C 1 ATOM 6787 O O . ILE B 1 487 ? 226.697 48.234 14.996 1.00 98.04 ? 485 ILE B O 1 ATOM 6788 C CB . ILE B 1 487 ? 224.287 49.920 16.311 1.00 97.26 ? 485 ILE B CB 1 ATOM 6789 C CG1 . ILE B 1 487 ? 225.239 49.972 17.510 1.00 98.08 ? 485 ILE B CG1 1 ATOM 6790 C CG2 . ILE B 1 487 ? 222.865 50.232 16.737 1.00 97.98 ? 485 ILE B CG2 1 ATOM 6791 C CD1 . ILE B 1 487 ? 226.470 50.825 17.295 1.00 107.52 ? 485 ILE B CD1 1 ATOM 6792 N N . PRO B 1 488 ? 225.396 48.772 13.231 1.00 92.18 ? 486 PRO B N 1 ATOM 6793 C CA . PRO B 1 488 ? 226.526 48.631 12.296 1.00 91.50 ? 486 PRO B CA 1 ATOM 6794 C C . PRO B 1 488 ? 227.371 49.898 12.050 1.00 94.27 ? 486 PRO B C 1 ATOM 6795 O O . PRO B 1 488 ? 227.945 50.042 10.965 1.00 93.81 ? 486 PRO B O 1 ATOM 6796 C CB . PRO B 1 488 ? 225.849 48.118 11.015 1.00 93.21 ? 486 PRO B CB 1 ATOM 6797 C CG . PRO B 1 488 ? 224.358 48.397 11.191 1.00 97.71 ? 486 PRO B CG 1 ATOM 6798 C CD . PRO B 1 488 ? 224.149 49.078 12.506 1.00 93.36 ? 486 PRO B CD 1 ATOM 6799 N N . TRP B 1 489 ? 227.498 50.792 13.058 1.00 90.13 ? 487 TRP B N 1 ATOM 6800 C CA . TRP B 1 489 ? 228.295 52.026 12.936 1.00 119.93 ? 487 TRP B CA 1 ATOM 6801 C C . TRP B 1 489 ? 228.828 52.538 14.272 1.00 111.70 ? 487 TRP B C 1 ATOM 6802 O O . TRP B 1 489 ? 228.810 51.825 15.271 1.00 65.32 ? 487 TRP B O 1 ATOM 6803 C CB . TRP B 1 489 ? 227.544 53.147 12.173 1.00 118.95 ? 487 TRP B CB 1 ATOM 6804 C CG . TRP B 1 489 ? 226.080 53.273 12.501 1.00 120.16 ? 487 TRP B CG 1 ATOM 6805 C CD1 . TRP B 1 489 ? 225.026 52.885 11.724 1.00 123.11 ? 487 TRP B CD1 1 ATOM 6806 C CD2 . TRP B 1 489 ? 225.514 53.815 13.703 1.00 119.97 ? 487 TRP B CD2 1 ATOM 6807 N NE1 . TRP B 1 489 ? 223.838 53.149 12.368 1.00 122.48 ? 487 TRP B NE1 1 ATOM 6808 C CE2 . TRP B 1 489 ? 224.109 53.717 13.586 1.00 123.81 ? 487 TRP B CE2 1 ATOM 6809 C CE3 . TRP B 1 489 ? 226.059 54.374 14.872 1.00 121.06 ? 487 TRP B CE3 1 ATOM 6810 C CZ2 . TRP B 1 489 ? 223.245 54.156 14.592 1.00 122.99 ? 487 TRP B CZ2 1 ATOM 6811 C CZ3 . TRP B 1 489 ? 225.202 54.798 15.870 1.00 122.38 ? 487 TRP B CZ3 1 ATOM 6812 C CH2 . TRP B 1 489 ? 223.816 54.677 15.731 1.00 123.00 ? 487 TRP B CH2 1 HETATM 6813 N N . GGL C 2 . ? 192.602 87.061 24.821 1.00 21.80 ? 601 GGL A N 1 HETATM 6814 C CA . GGL C 2 . ? 192.653 86.133 25.956 1.00 26.92 ? 601 GGL A CA 1 HETATM 6815 C C . GGL C 2 . ? 192.460 84.720 25.392 1.00 29.50 ? 601 GGL A C 1 HETATM 6816 O O . GGL C 2 . ? 192.458 84.467 24.199 1.00 34.34 ? 601 GGL A O 1 HETATM 6817 C CB . GGL C 2 . ? 191.500 86.415 26.943 1.00 30.02 ? 601 GGL A CB 1 HETATM 6818 C CG . GGL C 2 . ? 191.839 87.625 27.817 1.00 30.82 ? 601 GGL A CG 1 HETATM 6819 C CD . GGL C 2 . ? 190.595 88.427 28.082 1.00 32.31 ? 601 GGL A CD 1 HETATM 6820 O OE1 . GGL C 2 . ? 190.388 89.604 27.834 1.00 33.23 ? 601 GGL A OE1 1 HETATM 6821 O OE2 . GGL C 2 . ? 189.625 87.693 28.668 1.00 31.90 ? 601 GGL A OE2 1 HETATM 6822 O OXT . GGL C 2 . ? 192.279 83.677 26.222 1.00 29.90 ? 601 GGL A OXT 1 HETATM 6823 CL CL . CL D 3 . ? 185.509 82.210 29.490 1.00 36.29 ? 602 CL A CL 1 HETATM 6824 NA NA . NA E 4 . ? 163.986 94.994 17.645 1.00 63.29 1 603 NA A NA 1 HETATM 6825 C C1 . NAG F 5 . ? 218.540 101.367 19.305 1.00 69.37 ? 604 NAG A C1 1 HETATM 6826 C C2 . NAG F 5 . ? 218.303 102.786 19.827 1.00 68.52 ? 604 NAG A C2 1 HETATM 6827 C C3 . NAG F 5 . ? 218.415 103.769 18.658 1.00 72.57 ? 604 NAG A C3 1 HETATM 6828 C C4 . NAG F 5 . ? 219.726 103.567 17.893 1.00 73.64 ? 604 NAG A C4 1 HETATM 6829 C C5 . NAG F 5 . ? 219.822 102.119 17.417 1.00 72.82 ? 604 NAG A C5 1 HETATM 6830 C C6 . NAG F 5 . ? 221.082 101.780 16.642 1.00 75.47 ? 604 NAG A C6 1 HETATM 6831 C C7 . NAG F 5 . ? 216.747 103.169 21.718 1.00 63.88 ? 604 NAG A C7 1 HETATM 6832 C C8 . NAG F 5 . ? 215.310 103.392 22.087 1.00 61.58 ? 604 NAG A C8 1 HETATM 6833 N N2 . NAG F 5 . ? 216.980 102.870 20.427 1.00 65.25 ? 604 NAG A N2 1 HETATM 6834 O O3 . NAG F 5 . ? 218.315 105.105 19.142 1.00 73.54 ? 604 NAG A O3 1 HETATM 6835 O O4 . NAG F 5 . ? 219.796 104.463 16.787 1.00 74.85 ? 604 NAG A O4 1 HETATM 6836 O O5 . NAG F 5 . ? 219.753 101.238 18.551 1.00 70.80 ? 604 NAG A O5 1 HETATM 6837 O O6 . NAG F 5 . ? 222.259 101.697 17.450 1.00 76.59 ? 604 NAG A O6 1 HETATM 6838 O O7 . NAG F 5 . ? 217.649 103.252 22.547 1.00 64.79 ? 604 NAG A O7 1 HETATM 6839 C C1 . NAG G 5 . ? 215.637 94.934 46.901 1.00 76.64 ? 605 NAG A C1 1 HETATM 6840 C C2 . NAG G 5 . ? 216.348 95.280 48.209 1.00 81.92 ? 605 NAG A C2 1 HETATM 6841 C C3 . NAG G 5 . ? 217.107 96.593 48.021 1.00 83.60 ? 605 NAG A C3 1 HETATM 6842 C C4 . NAG G 5 . ? 218.125 96.447 46.890 1.00 85.10 ? 605 NAG A C4 1 HETATM 6843 C C5 . NAG G 5 . ? 217.435 95.970 45.610 1.00 82.83 ? 605 NAG A C5 1 HETATM 6844 C C6 . NAG G 5 . ? 218.396 95.605 44.497 1.00 81.89 ? 605 NAG A C6 1 HETATM 6845 C C7 . NAG G 5 . ? 215.278 94.305 50.208 1.00 83.88 ? 605 NAG A C7 1 HETATM 6846 C C8 . NAG G 5 . ? 214.494 94.599 51.450 1.00 82.57 ? 605 NAG A C8 1 HETATM 6847 N N2 . NAG G 5 . ? 215.463 95.343 49.364 1.00 84.04 ? 605 NAG A N2 1 HETATM 6848 O O3 . NAG G 5 . ? 217.773 96.942 49.231 1.00 83.23 ? 605 NAG A O3 1 HETATM 6849 O O4 . NAG G 5 . ? 218.819 97.675 46.668 1.00 85.59 ? 605 NAG A O4 1 HETATM 6850 O O5 . NAG G 5 . ? 216.634 94.800 45.873 1.00 80.38 ? 605 NAG A O5 1 HETATM 6851 O O6 . NAG G 5 . ? 219.125 94.406 44.758 1.00 81.55 ? 605 NAG A O6 1 HETATM 6852 O O7 . NAG G 5 . ? 215.743 93.188 49.985 1.00 84.77 ? 605 NAG A O7 1 HETATM 6853 N N . GGL H 2 . ? 201.667 57.135 20.366 1.00 36.44 ? 601 GGL B N 1 HETATM 6854 C CA . GGL H 2 . ? 200.887 57.676 19.248 1.00 34.57 ? 601 GGL B CA 1 HETATM 6855 C C . GGL H 2 . ? 199.911 58.703 19.833 1.00 36.23 ? 601 GGL B C 1 HETATM 6856 O O . GGL H 2 . ? 199.183 59.488 19.020 1.00 34.59 ? 601 GGL B O 1 HETATM 6857 C CB . GGL H 2 . ? 200.059 56.562 18.571 1.00 29.96 ? 601 GGL B CB 1 HETATM 6858 C CG . GGL H 2 . ? 200.889 55.875 17.484 1.00 29.32 ? 601 GGL B CG 1 HETATM 6859 C CD . GGL H 2 . ? 200.361 54.488 17.239 1.00 32.06 ? 601 GGL B CD 1 HETATM 6860 O OE1 . GGL H 2 . ? 199.027 54.475 17.033 1.00 30.96 ? 601 GGL B OE1 1 HETATM 6861 O OE2 . GGL H 2 . ? 200.982 53.438 17.211 1.00 35.11 ? 601 GGL B OE2 1 HETATM 6862 O OXT . GGL H 2 . ? 199.743 58.863 21.031 1.00 39.99 ? 601 GGL B OXT 1 HETATM 6863 CL CL . CL I 3 . ? 192.368 57.037 16.357 1.00 34.56 ? 602 CL B CL 1 HETATM 6864 NA NA . NA J 4 . ? 182.570 35.635 28.795 1.00 46.40 1 603 NA B NA 1 HETATM 6865 C C1 . NAG K 5 . ? 231.259 58.898 24.477 1.00 110.81 ? 604 NAG B C1 1 HETATM 6866 C C2 . NAG K 5 . ? 231.792 57.556 23.971 1.00 111.21 ? 604 NAG B C2 1 HETATM 6867 C C3 . NAG K 5 . ? 232.446 56.819 25.141 1.00 112.10 ? 604 NAG B C3 1 HETATM 6868 C C4 . NAG K 5 . ? 233.528 57.683 25.784 1.00 111.89 ? 604 NAG B C4 1 HETATM 6869 C C5 . NAG K 5 . ? 232.943 59.030 26.208 1.00 111.48 ? 604 NAG B C5 1 HETATM 6870 C C6 . NAG K 5 . ? 233.973 60.004 26.739 1.00 111.62 ? 604 NAG B C6 1 HETATM 6871 C C7 . NAG K 5 . ? 230.735 56.291 22.135 1.00 110.63 ? 604 NAG B C7 1 HETATM 6872 C C8 . NAG K 5 . ? 229.558 55.452 21.736 1.00 110.52 ? 604 NAG B C8 1 HETATM 6873 N N2 . NAG K 5 . ? 230.725 56.752 23.396 1.00 110.60 ? 604 NAG B N2 1 HETATM 6874 O O3 . NAG K 5 . ? 233.011 55.591 24.693 1.00 112.50 ? 604 NAG B O3 1 HETATM 6875 O O4 . NAG K 5 . ? 234.071 57.005 26.913 1.00 111.85 ? 604 NAG B O4 1 HETATM 6876 O O5 . NAG K 5 . ? 232.307 59.664 25.085 1.00 111.39 ? 604 NAG B O5 1 HETATM 6877 O O6 . NAG K 5 . ? 234.736 60.603 25.697 1.00 111.98 ? 604 NAG B O6 1 HETATM 6878 O O7 . NAG K 5 . ? 231.649 56.538 21.355 1.00 110.81 ? 604 NAG B O7 1 HETATM 6879 C C1 . NAG L 5 . ? 223.444 61.748 -3.316 1.00 116.00 ? 605 NAG B C1 1 HETATM 6880 C C2 . NAG L 5 . ? 223.947 61.542 -4.745 1.00 115.38 ? 605 NAG B C2 1 HETATM 6881 C C3 . NAG L 5 . ? 225.095 60.543 -4.606 1.00 117.03 ? 605 NAG B C3 1 HETATM 6882 C C4 . NAG L 5 . ? 226.217 61.144 -3.762 1.00 117.67 ? 605 NAG B C4 1 HETATM 6883 C C5 . NAG L 5 . ? 225.681 61.600 -2.403 1.00 117.46 ? 605 NAG B C5 1 HETATM 6884 C C6 . NAG L 5 . ? 226.657 62.443 -1.610 1.00 116.82 ? 605 NAG B C6 1 HETATM 6885 C C7 . NAG L 5 . ? 222.295 61.825 -6.559 1.00 111.93 ? 605 NAG B C7 1 HETATM 6886 C C8 . NAG L 5 . ? 221.263 61.139 -7.403 1.00 111.20 ? 605 NAG B C8 1 HETATM 6887 N N2 . NAG L 5 . ? 222.933 61.046 -5.663 1.00 113.02 ? 605 NAG B N2 1 HETATM 6888 O O3 . NAG L 5 . ? 225.590 60.177 -5.889 1.00 117.79 ? 605 NAG B O3 1 HETATM 6889 O O4 . NAG L 5 . ? 227.255 60.184 -3.592 1.00 117.65 ? 605 NAG B O4 1 HETATM 6890 O O5 . NAG L 5 . ? 224.489 62.391 -2.572 1.00 117.11 ? 605 NAG B O5 1 HETATM 6891 O O6 . NAG L 5 . ? 226.829 63.744 -2.164 1.00 116.29 ? 605 NAG B O6 1 HETATM 6892 O O7 . NAG L 5 . ? 222.539 63.025 -6.679 1.00 111.19 ? 605 NAG B O7 1 HETATM 6893 O O . HOH M 6 . ? 170.637 93.377 33.943 1.00 56.13 ? 701 HOH A O 1 HETATM 6894 O O . HOH M 6 . ? 208.983 96.973 38.741 1.00 90.92 ? 702 HOH A O 1 HETATM 6895 O O . HOH M 6 . ? 211.421 96.548 39.177 1.00 41.27 ? 703 HOH A O 1 HETATM 6896 O O . HOH M 6 . ? 197.613 83.355 21.826 1.00 26.27 ? 704 HOH A O 1 HETATM 6897 O O . HOH M 6 . ? 202.393 83.790 43.678 1.00 45.37 ? 705 HOH A O 1 HETATM 6898 O O . HOH M 6 . ? 190.755 93.534 30.286 1.00 54.11 ? 706 HOH A O 1 HETATM 6899 O O . HOH M 6 . ? 189.111 94.098 15.303 1.00 42.75 ? 707 HOH A O 1 HETATM 6900 O O . HOH M 6 . ? 182.056 90.372 7.748 1.00 34.73 ? 708 HOH A O 1 HETATM 6901 O O . HOH M 6 . ? 185.416 91.125 13.707 1.00 51.31 ? 709 HOH A O 1 HETATM 6902 O O . HOH M 6 . ? 209.700 92.609 39.221 1.00 35.29 ? 710 HOH A O 1 HETATM 6903 O O . HOH M 6 . ? 187.915 82.841 13.545 1.00 10.36 ? 711 HOH A O 1 HETATM 6904 O O . HOH M 6 . ? 180.427 99.207 19.459 1.00 33.79 ? 712 HOH A O 1 HETATM 6905 O O . HOH M 6 . ? 198.301 78.376 33.295 1.00 39.97 ? 713 HOH A O 1 HETATM 6906 O O . HOH M 6 . ? 194.618 89.769 19.479 1.00 28.90 ? 714 HOH A O 1 HETATM 6907 O O . HOH M 6 . ? 185.596 70.910 9.480 1.00 50.66 ? 715 HOH A O 1 HETATM 6908 O O . HOH M 6 . ? 199.242 71.918 33.997 1.00 38.19 ? 716 HOH A O 1 HETATM 6909 O O . HOH M 6 . ? 187.584 70.832 16.258 1.00 40.25 ? 717 HOH A O 1 HETATM 6910 O O . HOH M 6 . ? 199.882 88.292 29.686 1.00 42.17 ? 718 HOH A O 1 HETATM 6911 O O . HOH M 6 . ? 221.189 92.460 32.937 1.00 53.93 ? 719 HOH A O 1 HETATM 6912 O O . HOH M 6 . ? 166.782 79.985 19.340 1.00 40.20 ? 720 HOH A O 1 HETATM 6913 O O . HOH M 6 . ? 221.091 82.342 26.640 1.00 70.49 ? 721 HOH A O 1 HETATM 6914 O O . HOH M 6 . ? 197.812 82.680 19.367 1.00 29.65 ? 722 HOH A O 1 HETATM 6915 O O . HOH M 6 . ? 192.509 89.844 11.112 1.00 30.77 ? 723 HOH A O 1 HETATM 6916 O O . HOH M 6 . ? 161.664 90.474 5.947 1.00 39.72 ? 724 HOH A O 1 HETATM 6917 O O . HOH M 6 . ? 184.415 94.520 16.888 1.00 31.16 ? 725 HOH A O 1 HETATM 6918 O O . HOH M 6 . ? 182.085 86.002 45.498 1.00 46.87 ? 726 HOH A O 1 HETATM 6919 O O . HOH M 6 . ? 173.776 101.533 41.420 1.00 44.74 ? 727 HOH A O 1 HETATM 6920 O O . HOH M 6 . ? 217.126 92.218 28.845 1.00 45.56 ? 728 HOH A O 1 HETATM 6921 O O . HOH M 6 . ? 170.815 99.185 14.415 1.00 40.65 ? 729 HOH A O 1 HETATM 6922 O O . HOH M 6 . ? 170.085 73.585 20.992 1.00 58.02 ? 730 HOH A O 1 HETATM 6923 O O . HOH M 6 . ? 199.060 72.474 36.678 1.00 42.73 ? 731 HOH A O 1 HETATM 6924 O O . HOH M 6 . ? 208.336 76.196 39.424 1.00 38.36 ? 732 HOH A O 1 HETATM 6925 O O . HOH M 6 . ? 190.781 96.358 35.971 1.00 30.67 ? 733 HOH A O 1 HETATM 6926 O O . HOH M 6 . ? 171.274 94.445 9.067 1.00 41.20 ? 734 HOH A O 1 HETATM 6927 O O . HOH M 6 . ? 183.863 106.749 37.648 1.00 33.56 ? 735 HOH A O 1 HETATM 6928 O O . HOH M 6 . ? 199.867 90.539 41.752 1.00 43.79 ? 736 HOH A O 1 HETATM 6929 O O . HOH M 6 . ? 174.919 89.134 6.560 1.00 36.35 ? 737 HOH A O 1 HETATM 6930 O O . HOH M 6 . ? 206.673 104.980 37.982 1.00 45.42 ? 738 HOH A O 1 HETATM 6931 O O . HOH M 6 . ? 161.707 91.370 11.843 1.00 51.50 ? 739 HOH A O 1 HETATM 6932 O O . HOH M 6 . ? 206.426 103.037 33.547 1.00 54.45 ? 740 HOH A O 1 HETATM 6933 O O . HOH M 6 . ? 206.821 99.122 13.490 1.00 50.98 ? 741 HOH A O 1 HETATM 6934 O O . HOH M 6 . ? 214.946 83.079 47.021 1.00 44.60 ? 742 HOH A O 1 HETATM 6935 O O . HOH M 6 . ? 169.454 73.110 24.246 1.00 45.72 ? 743 HOH A O 1 HETATM 6936 O O . HOH M 6 . ? 177.092 105.525 24.345 1.00 47.39 ? 744 HOH A O 1 HETATM 6937 O O . HOH M 6 . ? 174.088 86.406 43.313 1.00 36.87 ? 745 HOH A O 1 HETATM 6938 O O . HOH M 6 . ? 178.365 77.975 36.600 1.00 44.06 ? 746 HOH A O 1 HETATM 6939 O O . HOH M 6 . ? 216.668 79.171 34.299 1.00 41.70 ? 747 HOH A O 1 HETATM 6940 O O . HOH M 6 . ? 207.865 80.617 27.461 1.00 20.02 ? 748 HOH A O 1 HETATM 6941 O O . HOH M 6 . ? 188.956 95.183 6.948 1.00 45.04 ? 749 HOH A O 1 HETATM 6942 O O . HOH M 6 . ? 176.224 79.719 39.046 1.00 46.38 ? 750 HOH A O 1 HETATM 6943 O O . HOH M 6 . ? 176.380 78.659 34.415 1.00 30.36 ? 751 HOH A O 1 HETATM 6944 O O . HOH M 6 . ? 167.100 78.018 15.354 1.00 50.71 ? 752 HOH A O 1 HETATM 6945 O O . HOH M 6 . ? 208.237 96.071 34.888 1.00 37.22 ? 753 HOH A O 1 HETATM 6946 O O . HOH M 6 . ? 164.721 92.745 18.335 1.00 52.86 ? 754 HOH A O 1 HETATM 6947 O O . HOH M 6 . ? 169.967 95.480 51.929 1.00 52.53 ? 755 HOH A O 1 HETATM 6948 O O . HOH M 6 . ? 198.614 80.289 43.691 1.00 28.30 ? 756 HOH A O 1 HETATM 6949 O O . HOH M 6 . ? 179.056 79.308 38.818 1.00 36.06 ? 757 HOH A O 1 HETATM 6950 O O . HOH M 6 . ? 193.160 85.073 9.887 1.00 36.90 ? 758 HOH A O 1 HETATM 6951 O O . HOH M 6 . ? 192.959 100.252 34.744 1.00 46.81 ? 759 HOH A O 1 HETATM 6952 O O . HOH M 6 . ? 178.636 108.734 38.949 1.00 58.25 ? 760 HOH A O 1 HETATM 6953 O O . HOH M 6 . ? 214.548 77.174 29.778 1.00 45.94 ? 761 HOH A O 1 HETATM 6954 O O . HOH M 6 . ? 179.430 69.989 11.399 1.00 44.74 ? 762 HOH A O 1 HETATM 6955 O O . HOH M 6 . ? 169.146 79.354 36.985 1.00 44.45 ? 763 HOH A O 1 HETATM 6956 O O . HOH M 6 . ? 177.893 103.083 48.032 1.00 34.49 ? 764 HOH A O 1 HETATM 6957 O O . HOH M 6 . ? 192.551 95.507 30.046 1.00 41.20 ? 765 HOH A O 1 HETATM 6958 O O . HOH M 6 . ? 199.455 84.920 45.785 1.00 30.62 ? 766 HOH A O 1 HETATM 6959 O O . HOH M 6 . ? 201.137 99.549 7.122 1.00 44.60 ? 767 HOH A O 1 HETATM 6960 O O . HOH M 6 . ? 220.461 88.181 19.879 1.00 42.50 ? 768 HOH A O 1 HETATM 6961 O O . HOH M 6 . ? 177.896 104.053 14.256 1.00 60.47 ? 769 HOH A O 1 HETATM 6962 O O . HOH M 6 . ? 173.986 98.618 14.374 1.00 41.24 ? 770 HOH A O 1 HETATM 6963 O O . HOH M 6 . ? 185.237 69.716 23.576 1.00 30.64 ? 771 HOH A O 1 HETATM 6964 O O . HOH M 6 . ? 196.954 79.566 27.799 1.00 34.28 ? 772 HOH A O 1 HETATM 6965 O O . HOH M 6 . ? 166.977 84.762 34.695 1.00 41.77 ? 773 HOH A O 1 HETATM 6966 O O . HOH M 6 . ? 182.594 104.369 30.323 1.00 32.93 ? 774 HOH A O 1 HETATM 6967 O O . HOH M 6 . ? 165.551 92.576 36.205 1.00 47.70 ? 775 HOH A O 1 HETATM 6968 O O . HOH M 6 . ? 214.737 95.257 35.541 1.00 55.01 ? 776 HOH A O 1 HETATM 6969 O O . HOH M 6 . ? 210.176 97.747 15.597 1.00 34.12 ? 777 HOH A O 1 HETATM 6970 O O . HOH M 6 . ? 181.518 107.270 38.991 1.00 32.37 ? 778 HOH A O 1 HETATM 6971 O O . HOH M 6 . ? 212.503 95.977 49.231 1.00 50.60 ? 779 HOH A O 1 HETATM 6972 O O . HOH M 6 . ? 185.460 98.890 25.511 1.00 40.78 ? 780 HOH A O 1 HETATM 6973 O O . HOH M 6 . ? 199.345 108.502 46.529 1.00 45.75 ? 781 HOH A O 1 HETATM 6974 O O . HOH M 6 . ? 188.084 90.661 36.130 1.00 28.31 ? 782 HOH A O 1 HETATM 6975 O O . HOH M 6 . ? 203.115 77.106 48.068 1.00 27.26 ? 783 HOH A O 1 HETATM 6976 O O . HOH M 6 . ? 212.749 84.222 12.348 1.00 36.78 ? 784 HOH A O 1 HETATM 6977 O O . HOH M 6 . ? 211.020 95.721 13.904 1.00 31.48 ? 785 HOH A O 1 HETATM 6978 O O . HOH M 6 . ? 164.582 91.328 7.790 1.00 55.43 ? 786 HOH A O 1 HETATM 6979 O O . HOH M 6 . ? 183.872 91.586 5.735 1.00 46.49 ? 787 HOH A O 1 HETATM 6980 O O . HOH M 6 . ? 170.213 100.539 27.858 1.00 45.13 ? 788 HOH A O 1 HETATM 6981 O O . HOH M 6 . ? 171.628 77.140 14.927 1.00 49.86 ? 789 HOH A O 1 HETATM 6982 O O . HOH M 6 . ? 193.678 79.761 27.447 1.00 14.16 ? 790 HOH A O 1 HETATM 6983 O O . HOH M 6 . ? 215.414 79.654 25.229 1.00 50.29 ? 791 HOH A O 1 HETATM 6984 O O . HOH M 6 . ? 188.793 113.295 18.598 1.00 69.23 ? 792 HOH A O 1 HETATM 6985 O O . HOH M 6 . ? 184.109 99.605 37.502 1.00 39.32 ? 793 HOH A O 1 HETATM 6986 O O . HOH M 6 . ? 181.557 77.054 16.941 1.00 28.87 ? 794 HOH A O 1 HETATM 6987 O O . HOH M 6 . ? 152.460 87.151 1.614 1.00 59.40 ? 795 HOH A O 1 HETATM 6988 O O . HOH M 6 . ? 191.715 103.602 21.282 1.00 37.83 ? 796 HOH A O 1 HETATM 6989 O O . HOH M 6 . ? 210.394 76.783 37.378 1.00 42.99 ? 797 HOH A O 1 HETATM 6990 O O . HOH M 6 . ? 167.910 101.030 20.756 1.00 43.98 ? 798 HOH A O 1 HETATM 6991 O O . HOH M 6 . ? 195.117 77.196 30.977 1.00 45.24 ? 799 HOH A O 1 HETATM 6992 O O . HOH M 6 . ? 220.129 81.927 24.152 1.00 43.65 ? 800 HOH A O 1 HETATM 6993 O O . HOH M 6 . ? 183.574 75.669 15.711 1.00 26.44 ? 801 HOH A O 1 HETATM 6994 O O . HOH M 6 . ? 175.243 94.002 8.405 1.00 15.53 ? 802 HOH A O 1 HETATM 6995 O O . HOH M 6 . ? 181.140 91.799 4.256 1.00 43.25 ? 803 HOH A O 1 HETATM 6996 O O . HOH M 6 . ? 195.940 83.583 12.496 1.00 42.58 ? 804 HOH A O 1 HETATM 6997 O O . HOH M 6 . ? 197.794 102.693 43.601 1.00 60.33 ? 805 HOH A O 1 HETATM 6998 O O . HOH M 6 . ? 191.875 99.572 25.833 1.00 48.03 ? 806 HOH A O 1 HETATM 6999 O O . HOH M 6 . ? 201.472 88.131 48.070 1.00 38.50 ? 807 HOH A O 1 HETATM 7000 O O . HOH M 6 . ? 160.726 100.264 20.030 1.00 46.52 ? 808 HOH A O 1 HETATM 7001 O O . HOH M 6 . ? 214.153 83.703 18.970 1.00 46.26 ? 809 HOH A O 1 HETATM 7002 O O . HOH M 6 . ? 207.809 104.707 16.862 1.00 44.55 ? 810 HOH A O 1 HETATM 7003 O O . HOH M 6 . ? 164.550 99.277 41.919 1.00 52.98 ? 811 HOH A O 1 HETATM 7004 O O . HOH M 6 . ? 185.723 94.099 14.627 1.00 40.75 ? 812 HOH A O 1 HETATM 7005 O O . HOH M 6 . ? 186.190 99.969 39.177 1.00 45.74 ? 813 HOH A O 1 HETATM 7006 O O . HOH M 6 . ? 216.917 89.469 35.941 1.00 61.47 ? 814 HOH A O 1 HETATM 7007 O O . HOH M 6 . ? 187.228 101.008 27.841 1.00 49.45 ? 815 HOH A O 1 HETATM 7008 O O . HOH M 6 . ? 161.013 93.012 19.389 1.00 43.70 ? 816 HOH A O 1 HETATM 7009 O O . HOH M 6 . ? 171.803 78.363 -0.200 1.00 49.11 ? 817 HOH A O 1 HETATM 7010 O O . HOH M 6 . ? 209.262 78.981 17.771 1.00 40.17 ? 818 HOH A O 1 HETATM 7011 O O . HOH M 6 . ? 220.483 94.516 31.350 1.00 49.04 ? 819 HOH A O 1 HETATM 7012 O O . HOH M 6 . ? 221.661 90.733 9.340 1.00 51.48 ? 820 HOH A O 1 HETATM 7013 O O . HOH N 6 . ? 181.673 35.354 20.068 1.00 72.56 ? 701 HOH B O 1 HETATM 7014 O O . HOH N 6 . ? 188.903 68.790 23.142 1.00 55.89 ? 702 HOH B O 1 HETATM 7015 O O . HOH N 6 . ? 219.476 70.520 11.094 1.00 53.01 ? 703 HOH B O 1 HETATM 7016 O O . HOH N 6 . ? 178.877 36.462 33.980 1.00 36.29 ? 704 HOH B O 1 HETATM 7017 O O . HOH N 6 . ? 176.010 48.475 27.335 1.00 37.23 ? 705 HOH B O 1 HETATM 7018 O O . HOH N 6 . ? 194.237 56.642 40.714 1.00 50.26 ? 706 HOH B O 1 HETATM 7019 O O . HOH N 6 . ? 186.118 39.990 12.490 1.00 39.45 ? 707 HOH B O 1 HETATM 7020 O O . HOH N 6 . ? 181.248 37.228 27.944 1.00 34.66 ? 708 HOH B O 1 HETATM 7021 O O . HOH N 6 . ? 197.467 71.937 2.213 1.00 38.79 ? 709 HOH B O 1 HETATM 7022 O O . HOH N 6 . ? 184.755 55.892 7.704 1.00 24.67 ? 710 HOH B O 1 HETATM 7023 O O . HOH N 6 . ? 195.300 48.634 38.321 1.00 31.87 ? 711 HOH B O 1 HETATM 7024 O O . HOH N 6 . ? 196.180 57.770 31.632 1.00 17.37 ? 712 HOH B O 1 HETATM 7025 O O . HOH N 6 . ? 198.353 40.226 25.606 1.00 53.83 ? 713 HOH B O 1 HETATM 7026 O O . HOH N 6 . ? 182.322 33.456 28.244 1.00 36.53 ? 714 HOH B O 1 HETATM 7027 O O . HOH N 6 . ? 182.205 62.470 37.890 1.00 30.03 ? 715 HOH B O 1 HETATM 7028 O O . HOH N 6 . ? 205.945 68.004 27.556 1.00 29.57 ? 716 HOH B O 1 HETATM 7029 O O . HOH N 6 . ? 223.280 42.801 0.663 1.00 59.34 ? 717 HOH B O 1 HETATM 7030 O O . HOH N 6 . ? 190.717 34.299 27.548 1.00 27.24 ? 718 HOH B O 1 HETATM 7031 O O . HOH N 6 . ? 203.648 63.026 23.470 1.00 57.99 ? 719 HOH B O 1 HETATM 7032 O O . HOH N 6 . ? 203.221 43.337 36.422 1.00 76.97 ? 720 HOH B O 1 HETATM 7033 O O . HOH N 6 . ? 196.631 57.415 9.486 1.00 36.90 ? 721 HOH B O 1 HETATM 7034 O O . HOH N 6 . ? 225.065 65.359 15.179 1.00 53.33 ? 722 HOH B O 1 HETATM 7035 O O . HOH N 6 . ? 183.725 50.799 3.387 1.00 34.38 ? 723 HOH B O 1 HETATM 7036 O O . HOH N 6 . ? 191.856 69.196 26.569 1.00 24.03 ? 724 HOH B O 1 HETATM 7037 O O . HOH N 6 . ? 182.306 38.474 19.758 1.00 45.50 ? 725 HOH B O 1 HETATM 7038 O O . HOH N 6 . ? 181.285 50.774 43.242 1.00 38.99 ? 726 HOH B O 1 HETATM 7039 O O . HOH N 6 . ? 208.678 74.443 10.620 1.00 42.47 ? 727 HOH B O 1 HETATM 7040 O O . HOH N 6 . ? 203.727 55.059 33.669 1.00 50.83 ? 728 HOH B O 1 HETATM 7041 O O . HOH N 6 . ? 177.322 60.598 14.999 1.00 43.96 ? 729 HOH B O 1 HETATM 7042 O O . HOH N 6 . ? 176.772 31.695 33.161 1.00 23.89 ? 730 HOH B O 1 HETATM 7043 O O . HOH N 6 . ? 207.916 59.678 15.306 1.00 39.06 ? 731 HOH B O 1 HETATM 7044 O O . HOH N 6 . ? 208.294 57.016 2.892 1.00 44.24 ? 732 HOH B O 1 HETATM 7045 O O . HOH N 6 . ? 201.785 43.453 19.998 1.00 34.90 ? 733 HOH B O 1 HETATM 7046 O O . HOH N 6 . ? 186.109 66.057 10.278 1.00 33.14 ? 734 HOH B O 1 HETATM 7047 O O . HOH N 6 . ? 206.936 64.343 0.904 1.00 51.22 ? 735 HOH B O 1 HETATM 7048 O O . HOH N 6 . ? 205.024 56.264 25.579 1.00 30.58 ? 736 HOH B O 1 HETATM 7049 O O . HOH N 6 . ? 184.159 47.639 2.972 1.00 31.47 ? 737 HOH B O 1 HETATM 7050 O O . HOH N 6 . ? 175.766 55.723 26.173 1.00 51.65 ? 738 HOH B O 1 HETATM 7051 O O . HOH N 6 . ? 203.790 63.586 26.086 1.00 37.32 ? 739 HOH B O 1 HETATM 7052 O O . HOH N 6 . ? 201.798 38.006 34.914 1.00 46.47 ? 740 HOH B O 1 HETATM 7053 O O . HOH N 6 . ? 186.098 67.460 22.646 1.00 32.34 ? 741 HOH B O 1 HETATM 7054 O O . HOH N 6 . ? 210.424 70.417 16.918 1.00 30.86 ? 742 HOH B O 1 HETATM 7055 O O . HOH N 6 . ? 184.786 68.059 29.680 1.00 17.78 ? 743 HOH B O 1 HETATM 7056 O O . HOH N 6 . ? 183.636 46.046 -6.362 1.00 41.88 ? 744 HOH B O 1 HETATM 7057 O O . HOH N 6 . ? 180.560 38.084 16.205 1.00 31.92 ? 745 HOH B O 1 HETATM 7058 O O . HOH N 6 . ? 196.763 53.497 -5.406 1.00 42.32 ? 746 HOH B O 1 HETATM 7059 O O . HOH N 6 . ? 200.927 65.368 17.474 1.00 39.34 ? 747 HOH B O 1 HETATM 7060 O O . HOH N 6 . ? 174.150 56.142 22.801 1.00 42.55 ? 748 HOH B O 1 HETATM 7061 O O . HOH N 6 . ? 174.013 55.540 36.657 1.00 36.76 ? 749 HOH B O 1 HETATM 7062 O O . HOH N 6 . ? 175.194 32.128 28.097 1.00 49.10 ? 750 HOH B O 1 HETATM 7063 O O . HOH N 6 . ? 189.634 49.591 -1.702 1.00 31.10 ? 751 HOH B O 1 HETATM 7064 O O . HOH N 6 . ? 182.805 33.521 21.448 1.00 32.92 ? 752 HOH B O 1 HETATM 7065 O O . HOH N 6 . ? 198.486 50.384 6.053 1.00 50.13 ? 753 HOH B O 1 HETATM 7066 O O . HOH N 6 . ? 182.660 55.347 12.075 1.00 18.93 ? 754 HOH B O 1 HETATM 7067 O O . HOH N 6 . ? 172.611 38.636 42.491 1.00 31.71 ? 755 HOH B O 1 HETATM 7068 O O . HOH N 6 . ? 182.957 54.276 7.037 1.00 50.18 ? 756 HOH B O 1 HETATM 7069 O O . HOH N 6 . ? 182.995 44.442 4.481 1.00 44.35 ? 757 HOH B O 1 HETATM 7070 O O . HOH N 6 . ? 179.372 34.673 26.679 1.00 41.38 ? 758 HOH B O 1 HETATM 7071 O O . HOH N 6 . ? 192.812 31.760 16.227 1.00 31.86 ? 759 HOH B O 1 HETATM 7072 O O . HOH N 6 . ? 208.616 42.588 27.482 1.00 46.41 ? 760 HOH B O 1 HETATM 7073 O O . HOH N 6 . ? 190.130 34.655 32.144 1.00 39.94 ? 761 HOH B O 1 HETATM 7074 O O . HOH N 6 . ? 187.278 67.872 17.595 1.00 55.60 ? 762 HOH B O 1 HETATM 7075 O O . HOH N 6 . ? 195.298 36.918 36.438 1.00 35.30 ? 763 HOH B O 1 HETATM 7076 O O . HOH N 6 . ? 183.345 56.989 9.705 1.00 26.59 ? 764 HOH B O 1 HETATM 7077 O O . HOH N 6 . ? 221.371 49.416 -0.295 1.00 45.66 ? 765 HOH B O 1 HETATM 7078 O O . HOH N 6 . ? 173.131 38.494 31.069 1.00 32.42 ? 766 HOH B O 1 HETATM 7079 O O . HOH N 6 . ? 181.439 38.273 37.859 1.00 36.24 ? 767 HOH B O 1 HETATM 7080 O O . HOH N 6 . ? 186.021 38.522 -6.435 1.00 13.05 ? 768 HOH B O 1 HETATM 7081 O O . HOH N 6 . ? 190.957 48.529 -6.882 1.00 34.60 ? 769 HOH B O 1 HETATM 7082 O O . HOH N 6 . ? 172.960 38.752 47.900 1.00 51.50 ? 770 HOH B O 1 HETATM 7083 O O . HOH N 6 . ? 192.382 34.677 3.478 1.00 30.22 ? 771 HOH B O 1 HETATM 7084 O O . HOH N 6 . ? 196.501 59.962 7.955 1.00 27.86 ? 772 HOH B O 1 HETATM 7085 O O . HOH N 6 . ? 198.299 38.478 -3.703 1.00 34.04 ? 773 HOH B O 1 HETATM 7086 O O . HOH N 6 . ? 181.031 38.040 10.001 1.00 44.11 ? 774 HOH B O 1 HETATM 7087 O O . HOH N 6 . ? 228.646 58.161 17.527 1.00 43.43 ? 775 HOH B O 1 HETATM 7088 O O . HOH N 6 . ? 200.408 40.602 -2.340 1.00 38.99 ? 776 HOH B O 1 HETATM 7089 O O . HOH N 6 . ? 175.353 50.061 30.953 1.00 49.69 ? 777 HOH B O 1 HETATM 7090 O O . HOH N 6 . ? 172.965 48.623 24.157 1.00 56.92 ? 778 HOH B O 1 HETATM 7091 O O . HOH N 6 . ? 191.257 42.165 37.858 1.00 5.59 ? 779 HOH B O 1 HETATM 7092 O O . HOH N 6 . ? 191.011 53.681 42.716 1.00 45.80 ? 780 HOH B O 1 HETATM 7093 O O . HOH N 6 . ? 188.500 36.044 -8.132 1.00 47.29 ? 781 HOH B O 1 HETATM 7094 O O . HOH N 6 . ? 204.348 47.432 13.822 1.00 55.13 ? 782 HOH B O 1 HETATM 7095 O O . HOH N 6 . ? 188.111 38.757 36.919 1.00 44.24 ? 783 HOH B O 1 HETATM 7096 O O . HOH N 6 . ? 196.367 64.049 38.082 1.00 44.69 ? 784 HOH B O 1 HETATM 7097 O O . HOH N 6 . ? 178.335 45.504 11.753 1.00 31.62 ? 785 HOH B O 1 HETATM 7098 O O . HOH N 6 . ? 202.061 44.100 38.746 1.00 58.36 ? 786 HOH B O 1 HETATM 7099 O O . HOH N 6 . ? 196.197 50.205 -3.400 1.00 47.35 ? 787 HOH B O 1 HETATM 7100 O O . HOH N 6 . ? 178.736 53.307 31.840 1.00 46.05 ? 788 HOH B O 1 HETATM 7101 O O . HOH N 6 . ? 201.943 75.747 20.548 1.00 49.89 ? 789 HOH B O 1 HETATM 7102 O O . HOH N 6 . ? 192.611 37.038 31.296 1.00 30.97 ? 790 HOH B O 1 HETATM 7103 O O . HOH N 6 . ? 199.001 51.350 9.131 1.00 18.05 ? 791 HOH B O 1 HETATM 7104 O O . HOH N 6 . ? 184.020 53.709 4.062 1.00 32.27 ? 792 HOH B O 1 HETATM 7105 O O . HOH N 6 . ? 188.138 61.692 30.549 1.00 29.01 ? 793 HOH B O 1 HETATM 7106 O O . HOH N 6 . ? 167.652 40.677 34.888 1.00 52.68 ? 794 HOH B O 1 HETATM 7107 O O . HOH N 6 . ? 208.455 46.401 19.979 1.00 41.09 ? 795 HOH B O 1 HETATM 7108 O O . HOH N 6 . ? 187.067 59.475 29.006 1.00 25.94 ? 796 HOH B O 1 HETATM 7109 O O . HOH N 6 . ? 198.282 63.558 17.847 1.00 13.60 ? 797 HOH B O 1 HETATM 7110 O O . HOH N 6 . ? 207.310 40.263 34.343 1.00 50.16 ? 798 HOH B O 1 HETATM 7111 O O . HOH N 6 . ? 189.585 34.181 -0.360 1.00 32.80 ? 799 HOH B O 1 HETATM 7112 O O . HOH N 6 . ? 172.667 44.247 21.649 1.00 42.93 ? 800 HOH B O 1 HETATM 7113 O O . HOH N 6 . ? 198.034 73.394 24.123 1.00 40.31 ? 801 HOH B O 1 HETATM 7114 O O . HOH N 6 . ? 175.349 32.814 45.385 1.00 44.97 ? 802 HOH B O 1 HETATM 7115 O O . HOH N 6 . ? 173.564 31.613 37.326 1.00 49.22 ? 803 HOH B O 1 HETATM 7116 O O . HOH N 6 . ? 190.718 59.483 37.861 1.00 38.55 ? 804 HOH B O 1 HETATM 7117 O O . HOH N 6 . ? 176.901 34.553 27.777 1.00 41.98 ? 805 HOH B O 1 HETATM 7118 O O . HOH N 6 . ? 205.694 35.769 6.353 1.00 49.78 ? 806 HOH B O 1 HETATM 7119 O O . HOH N 6 . ? 180.599 31.212 28.418 1.00 41.26 ? 807 HOH B O 1 HETATM 7120 O O . HOH N 6 . ? 183.490 58.423 5.682 1.00 46.22 ? 808 HOH B O 1 HETATM 7121 O O . HOH N 6 . ? 175.505 50.497 10.649 1.00 56.27 ? 809 HOH B O 1 HETATM 7122 O O . HOH N 6 . ? 194.578 37.625 -9.316 1.00 45.85 ? 810 HOH B O 1 HETATM 7123 O O . HOH N 6 . ? 171.558 41.226 22.636 1.00 53.39 ? 811 HOH B O 1 HETATM 7124 O O . HOH N 6 . ? 196.468 47.661 40.814 1.00 40.25 ? 812 HOH B O 1 HETATM 7125 O O . HOH N 6 . ? 194.968 33.502 35.663 1.00 45.23 ? 813 HOH B O 1 HETATM 7126 O O . HOH N 6 . ? 204.373 44.463 33.959 1.00 64.03 ? 814 HOH B O 1 HETATM 7127 O O . HOH N 6 . ? 195.921 34.179 31.256 1.00 43.20 ? 815 HOH B O 1 HETATM 7128 O O . HOH N 6 . ? 181.825 36.434 40.329 1.00 25.65 ? 816 HOH B O 1 HETATM 7129 O O . HOH N 6 . ? 193.418 35.984 34.360 1.00 46.63 ? 817 HOH B O 1 HETATM 7130 O O . HOH N 6 . ? 204.071 58.969 35.279 1.00 63.96 ? 818 HOH B O 1 HETATM 7131 O O . HOH N 6 . ? 206.826 45.042 32.143 1.00 48.24 ? 819 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 MET 1 -1 ? ? ? A . n A 1 2 ALA 2 0 ? ? ? A . n A 1 3 LEU 3 1 ? ? ? A . n A 1 4 GLY 4 2 ? ? ? A . n A 1 5 SER 5 3 ? ? ? A . n A 1 6 LEU 6 4 ? ? ? A . n A 1 7 LEU 7 5 ? ? ? A . n A 1 8 ALA 8 6 ? ? ? A . n A 1 9 LEU 9 7 ? ? ? A . n A 1 10 LEU 10 8 ? ? ? A . n A 1 11 ALA 11 9 ? ? ? A . n A 1 12 LEU 12 10 ? ? ? A . n A 1 13 LEU 13 11 ? ? ? A . n A 1 14 LEU 14 12 ? ? ? A . n A 1 15 LEU 15 13 ? ? ? A . n A 1 16 TRP 16 14 ? ? ? A . n A 1 17 GLY 17 15 ? ? ? A . n A 1 18 ALA 18 16 ? ? ? A . n A 1 19 VAL 19 17 ? ? ? A . n A 1 20 ALA 20 18 ? ? ? A . n A 1 21 GLU 21 19 ? ? ? A . n A 1 22 GLY 22 20 ? ? ? A . n A 1 23 PRO 23 21 ? ? ? A . n A 1 24 ALA 24 22 ? ? ? A . n A 1 25 LYS 25 23 23 LYS LYS A . n A 1 26 LYS 26 24 24 LYS LYS A . n A 1 27 VAL 27 25 25 VAL VAL A . n A 1 28 LEU 28 26 26 LEU LEU A . n A 1 29 THR 29 27 27 THR THR A . n A 1 30 LEU 30 28 28 LEU LEU A . n A 1 31 GLU 31 29 29 GLU GLU A . n A 1 32 GLY 32 30 30 GLY GLY A . n A 1 33 ASP 33 31 31 ASP ASP A . n A 1 34 LEU 34 32 32 LEU LEU A . n A 1 35 VAL 35 33 33 VAL VAL A . n A 1 36 LEU 36 34 34 LEU LEU A . n A 1 37 GLY 37 35 35 GLY GLY A . n A 1 38 GLY 38 36 36 GLY GLY A . n A 1 39 LEU 39 37 37 LEU LEU A . n A 1 40 PHE 40 38 38 PHE PHE A . n A 1 41 PRO 41 39 39 PRO PRO A . n A 1 42 VAL 42 40 40 VAL VAL A . n A 1 43 HIS 43 41 41 HIS HIS A . n A 1 44 GLN 44 42 42 GLN GLN A . n A 1 45 LYS 45 43 43 LYS LYS A . n A 1 46 GLY 46 44 44 GLY GLY A . n A 1 47 GLY 47 45 45 GLY GLY A . n A 1 48 PRO 48 46 46 PRO PRO A . n A 1 49 ALA 49 47 47 ALA ALA A . n A 1 50 GLU 50 48 48 GLU GLU A . n A 1 51 ASP 51 49 49 ASP ASP A . n A 1 52 CYS 52 50 50 CYS CYS A . n A 1 53 GLY 53 51 51 GLY GLY A . n A 1 54 PRO 54 52 52 PRO PRO A . n A 1 55 VAL 55 53 53 VAL VAL A . n A 1 56 ASN 56 54 54 ASN ASN A . n A 1 57 GLU 57 55 55 GLU GLU A . n A 1 58 HIS 58 56 56 HIS HIS A . n A 1 59 ARG 59 57 57 ARG ARG A . n A 1 60 GLY 60 58 58 GLY GLY A . n A 1 61 ILE 61 59 59 ILE ILE A . n A 1 62 GLN 62 60 60 GLN GLN A . n A 1 63 ARG 63 61 61 ARG ARG A . n A 1 64 LEU 64 62 62 LEU LEU A . n A 1 65 GLU 65 63 63 GLU GLU A . n A 1 66 ALA 66 64 64 ALA ALA A . n A 1 67 MET 67 65 65 MET MET A . n A 1 68 LEU 68 66 66 LEU LEU A . n A 1 69 PHE 69 67 67 PHE PHE A . n A 1 70 ALA 70 68 68 ALA ALA A . n A 1 71 LEU 71 69 69 LEU LEU A . n A 1 72 ASP 72 70 70 ASP ASP A . n A 1 73 ARG 73 71 71 ARG ARG A . n A 1 74 ILE 74 72 72 ILE ILE A . n A 1 75 ASN 75 73 73 ASN ASN A . n A 1 76 ARG 76 74 74 ARG ARG A . n A 1 77 ASP 77 75 75 ASP ASP A . n A 1 78 PRO 78 76 76 PRO PRO A . n A 1 79 HIS 79 77 77 HIS HIS A . n A 1 80 LEU 80 78 78 LEU LEU A . n A 1 81 LEU 81 79 79 LEU LEU A . n A 1 82 PRO 82 80 80 PRO PRO A . n A 1 83 GLY 83 81 81 GLY GLY A . n A 1 84 VAL 84 82 82 VAL VAL A . n A 1 85 ARG 85 83 83 ARG ARG A . n A 1 86 LEU 86 84 84 LEU LEU A . n A 1 87 GLY 87 85 85 GLY GLY A . n A 1 88 ALA 88 86 86 ALA ALA A . n A 1 89 HIS 89 87 87 HIS HIS A . n A 1 90 ILE 90 88 88 ILE ILE A . n A 1 91 LEU 91 89 89 LEU LEU A . n A 1 92 ASP 92 90 90 ASP ASP A . n A 1 93 SER 93 91 91 SER SER A . n A 1 94 CYS 94 92 92 CYS CYS A . n A 1 95 SER 95 93 93 SER SER A . n A 1 96 LYS 96 94 94 LYS LYS A . n A 1 97 ASP 97 95 95 ASP ASP A . n A 1 98 THR 98 96 96 THR THR A . n A 1 99 HIS 99 97 97 HIS HIS A . n A 1 100 ALA 100 98 98 ALA ALA A . n A 1 101 LEU 101 99 99 LEU LEU A . n A 1 102 GLU 102 100 100 GLU GLU A . n A 1 103 GLN 103 101 101 GLN GLN A . n A 1 104 ALA 104 102 102 ALA ALA A . n A 1 105 LEU 105 103 103 LEU LEU A . n A 1 106 ASP 106 104 104 ASP ASP A . n A 1 107 PHE 107 105 105 PHE PHE A . n A 1 108 VAL 108 106 106 VAL VAL A . n A 1 109 ARG 109 107 107 ARG ARG A . n A 1 110 ALA 110 108 108 ALA ALA A . n A 1 111 SER 111 109 109 SER SER A . n A 1 112 LEU 112 110 ? ? ? A . n A 1 113 SER 113 111 ? ? ? A . n A 1 114 ARG 114 112 ? ? ? A . n A 1 115 GLY 115 113 ? ? ? A . n A 1 116 ALA 116 114 ? ? ? A . n A 1 117 ASP 117 115 ? ? ? A . n A 1 118 GLY 118 116 ? ? ? A . n A 1 119 SER 119 117 ? ? ? A . n A 1 120 ARG 120 118 ? ? ? A . n A 1 121 HIS 121 119 ? ? ? A . n A 1 122 ILE 122 120 ? ? ? A . n A 1 123 CYS 123 121 ? ? ? A . n A 1 124 PRO 124 122 ? ? ? A . n A 1 125 ASP 125 123 ? ? ? A . n A 1 126 GLY 126 124 ? ? ? A . n A 1 127 SER 127 125 ? ? ? A . n A 1 128 TYR 128 126 ? ? ? A . n A 1 129 ALA 129 127 ? ? ? A . n A 1 130 THR 130 128 ? ? ? A . n A 1 131 HIS 131 129 ? ? ? A . n A 1 132 GLY 132 130 ? ? ? A . n A 1 133 ASP 133 131 ? ? ? A . n A 1 134 ALA 134 132 ? ? ? A . n A 1 135 PRO 135 133 ? ? ? A . n A 1 136 THR 136 134 134 THR THR A . n A 1 137 ALA 137 135 135 ALA ALA A . n A 1 138 ILE 138 136 136 ILE ILE A . n A 1 139 THR 139 137 137 THR THR A . n A 1 140 GLY 140 138 138 GLY GLY A . n A 1 141 VAL 141 139 139 VAL VAL A . n A 1 142 ILE 142 140 140 ILE ILE A . n A 1 143 GLY 143 141 141 GLY GLY A . n A 1 144 GLY 144 142 142 GLY GLY A . n A 1 145 SER 145 143 143 SER SER A . n A 1 146 TYR 146 144 144 TYR TYR A . n A 1 147 SER 147 145 145 SER SER A . n A 1 148 ASP 148 146 146 ASP ASP A . n A 1 149 VAL 149 147 147 VAL VAL A . n A 1 150 SER 150 148 148 SER SER A . n A 1 151 ILE 151 149 149 ILE ILE A . n A 1 152 GLN 152 150 150 GLN GLN A . n A 1 153 VAL 153 151 151 VAL VAL A . n A 1 154 ALA 154 152 152 ALA ALA A . n A 1 155 ASN 155 153 153 ASN ASN A . n A 1 156 LEU 156 154 154 LEU LEU A . n A 1 157 LEU 157 155 155 LEU LEU A . n A 1 158 ARG 158 156 156 ARG ARG A . n A 1 159 LEU 159 157 157 LEU LEU A . n A 1 160 PHE 160 158 158 PHE PHE A . n A 1 161 GLN 161 159 159 GLN GLN A . n A 1 162 ILE 162 160 160 ILE ILE A . n A 1 163 PRO 163 161 161 PRO PRO A . n A 1 164 GLN 164 162 162 GLN GLN A . n A 1 165 ILE 165 163 163 ILE ILE A . n A 1 166 SER 166 164 164 SER SER A . n A 1 167 TYR 167 165 165 TYR TYR A . n A 1 168 ALA 168 166 166 ALA ALA A . n A 1 169 SER 169 167 167 SER SER A . n A 1 170 THR 170 168 168 THR THR A . n A 1 171 SER 171 169 169 SER SER A . n A 1 172 ALA 172 170 170 ALA ALA A . n A 1 173 LYS 173 171 171 LYS LYS A . n A 1 174 LEU 174 172 172 LEU LEU A . n A 1 175 SER 175 173 173 SER SER A . n A 1 176 ASP 176 174 174 ASP ASP A . n A 1 177 LYS 177 175 175 LYS LYS A . n A 1 178 SER 178 176 176 SER SER A . n A 1 179 ARG 179 177 177 ARG ARG A . n A 1 180 TYR 180 178 178 TYR TYR A . n A 1 181 ASP 181 179 179 ASP ASP A . n A 1 182 TYR 182 180 180 TYR TYR A . n A 1 183 PHE 183 181 181 PHE PHE A . n A 1 184 ALA 184 182 182 ALA ALA A . n A 1 185 ARG 185 183 183 ARG ARG A . n A 1 186 THR 186 184 184 THR THR A . n A 1 187 VAL 187 185 185 VAL VAL A . n A 1 188 PRO 188 186 186 PRO PRO A . n A 1 189 PRO 189 187 187 PRO PRO A . n A 1 190 ASP 190 188 188 ASP ASP A . n A 1 191 PHE 191 189 189 PHE PHE A . n A 1 192 PHE 192 190 190 PHE PHE A . n A 1 193 GLN 193 191 191 GLN GLN A . n A 1 194 ALA 194 192 192 ALA ALA A . n A 1 195 LYS 195 193 193 LYS LYS A . n A 1 196 ALA 196 194 194 ALA ALA A . n A 1 197 MET 197 195 195 MET MET A . n A 1 198 ALA 198 196 196 ALA ALA A . n A 1 199 GLU 199 197 197 GLU GLU A . n A 1 200 ILE 200 198 198 ILE ILE A . n A 1 201 LEU 201 199 199 LEU LEU A . n A 1 202 ARG 202 200 200 ARG ARG A . n A 1 203 PHE 203 201 201 PHE PHE A . n A 1 204 PHE 204 202 202 PHE PHE A . n A 1 205 ASN 205 203 203 ASN ASN A . n A 1 206 TRP 206 204 204 TRP TRP A . n A 1 207 THR 207 205 205 THR THR A . n A 1 208 TYR 208 206 206 TYR TYR A . n A 1 209 VAL 209 207 207 VAL VAL A . n A 1 210 SER 210 208 208 SER SER A . n A 1 211 THR 211 209 209 THR THR A . n A 1 212 VAL 212 210 210 VAL VAL A . n A 1 213 ALA 213 211 211 ALA ALA A . n A 1 214 SER 214 212 212 SER SER A . n A 1 215 GLU 215 213 213 GLU GLU A . n A 1 216 GLY 216 214 214 GLY GLY A . n A 1 217 ASP 217 215 215 ASP ASP A . n A 1 218 TYR 218 216 216 TYR TYR A . n A 1 219 GLY 219 217 217 GLY GLY A . n A 1 220 GLU 220 218 218 GLU GLU A . n A 1 221 THR 221 219 219 THR THR A . n A 1 222 GLY 222 220 220 GLY GLY A . n A 1 223 ILE 223 221 221 ILE ILE A . n A 1 224 GLU 224 222 222 GLU GLU A . n A 1 225 ALA 225 223 223 ALA ALA A . n A 1 226 PHE 226 224 224 PHE PHE A . n A 1 227 GLU 227 225 225 GLU GLU A . n A 1 228 LEU 228 226 226 LEU LEU A . n A 1 229 GLU 229 227 227 GLU GLU A . n A 1 230 ALA 230 228 228 ALA ALA A . n A 1 231 ARG 231 229 229 ARG ARG A . n A 1 232 ALA 232 230 230 ALA ALA A . n A 1 233 ARG 233 231 231 ARG ARG A . n A 1 234 ASN 234 232 232 ASN ASN A . n A 1 235 ILE 235 233 233 ILE ILE A . n A 1 236 SER 236 234 234 SER SER A . n A 1 237 VAL 237 235 235 VAL VAL A . n A 1 238 ALA 238 236 236 ALA ALA A . n A 1 239 THR 239 237 237 THR THR A . n A 1 240 SER 240 238 238 SER SER A . n A 1 241 GLU 241 239 239 GLU GLU A . n A 1 242 LYS 242 240 240 LYS LYS A . n A 1 243 VAL 243 241 241 VAL VAL A . n A 1 244 GLY 244 242 242 GLY GLY A . n A 1 245 ARG 245 243 243 ARG ARG A . n A 1 246 ALA 246 244 244 ALA ALA A . n A 1 247 MET 247 245 245 MET MET A . n A 1 248 SER 248 246 246 SER SER A . n A 1 249 ARG 249 247 247 ARG ARG A . n A 1 250 ALA 250 248 248 ALA ALA A . n A 1 251 ALA 251 249 249 ALA ALA A . n A 1 252 PHE 252 250 250 PHE PHE A . n A 1 253 GLU 253 251 251 GLU GLU A . n A 1 254 GLY 254 252 252 GLY GLY A . n A 1 255 VAL 255 253 253 VAL VAL A . n A 1 256 VAL 256 254 254 VAL VAL A . n A 1 257 ARG 257 255 255 ARG ARG A . n A 1 258 ALA 258 256 256 ALA ALA A . n A 1 259 LEU 259 257 257 LEU LEU A . n A 1 260 LEU 260 258 258 LEU LEU A . n A 1 261 GLN 261 259 259 GLN GLN A . n A 1 262 LYS 262 260 260 LYS LYS A . n A 1 263 PRO 263 261 261 PRO PRO A . n A 1 264 SER 264 262 262 SER SER A . n A 1 265 ALA 265 263 263 ALA ALA A . n A 1 266 ARG 266 264 264 ARG ARG A . n A 1 267 VAL 267 265 265 VAL VAL A . n A 1 268 ALA 268 266 266 ALA ALA A . n A 1 269 VAL 269 267 267 VAL VAL A . n A 1 270 LEU 270 268 268 LEU LEU A . n A 1 271 PHE 271 269 269 PHE PHE A . n A 1 272 THR 272 270 270 THR THR A . n A 1 273 ARG 273 271 271 ARG ARG A . n A 1 274 SER 274 272 272 SER SER A . n A 1 275 GLU 275 273 273 GLU GLU A . n A 1 276 ASP 276 274 274 ASP ASP A . n A 1 277 ALA 277 275 275 ALA ALA A . n A 1 278 ARG 278 276 276 ARG ARG A . n A 1 279 GLU 279 277 277 GLU GLU A . n A 1 280 LEU 280 278 278 LEU LEU A . n A 1 281 LEU 281 279 279 LEU LEU A . n A 1 282 ALA 282 280 280 ALA ALA A . n A 1 283 ALA 283 281 281 ALA ALA A . n A 1 284 SER 284 282 282 SER SER A . n A 1 285 GLN 285 283 283 GLN GLN A . n A 1 286 ARG 286 284 284 ARG ARG A . n A 1 287 LEU 287 285 285 LEU LEU A . n A 1 288 ASN 288 286 286 ASN ASN A . n A 1 289 ALA 289 287 287 ALA ALA A . n A 1 290 SER 290 288 288 SER SER A . n A 1 291 PHE 291 289 289 PHE PHE A . n A 1 292 THR 292 290 290 THR THR A . n A 1 293 TRP 293 291 291 TRP TRP A . n A 1 294 VAL 294 292 292 VAL VAL A . n A 1 295 ALA 295 293 293 ALA ALA A . n A 1 296 SER 296 294 294 SER SER A . n A 1 297 ASP 297 295 295 ASP ASP A . n A 1 298 GLY 298 296 296 GLY GLY A . n A 1 299 TRP 299 297 297 TRP TRP A . n A 1 300 GLY 300 298 298 GLY GLY A . n A 1 301 ALA 301 299 299 ALA ALA A . n A 1 302 LEU 302 300 300 LEU LEU A . n A 1 303 GLU 303 301 301 GLU GLU A . n A 1 304 GLU 304 302 302 GLU GLU A . n A 1 305 VAL 305 303 303 VAL VAL A . n A 1 306 VAL 306 304 304 VAL VAL A . n A 1 307 ALA 307 305 305 ALA ALA A . n A 1 308 GLY 308 306 306 GLY GLY A . n A 1 309 SER 309 307 307 SER SER A . n A 1 310 GLU 310 308 308 GLU GLU A . n A 1 311 GLY 311 309 309 GLY GLY A . n A 1 312 ALA 312 310 310 ALA ALA A . n A 1 313 ALA 313 311 311 ALA ALA A . n A 1 314 GLU 314 312 312 GLU GLU A . n A 1 315 GLY 315 313 313 GLY GLY A . n A 1 316 ALA 316 314 314 ALA ALA A . n A 1 317 ILE 317 315 315 ILE ILE A . n A 1 318 THR 318 316 316 THR THR A . n A 1 319 ILE 319 317 317 ILE ILE A . n A 1 320 GLU 320 318 318 GLU GLU A . n A 1 321 LEU 321 319 319 LEU LEU A . n A 1 322 ALA 322 320 320 ALA ALA A . n A 1 323 SER 323 321 321 SER SER A . n A 1 324 TYR 324 322 322 TYR TYR A . n A 1 325 PRO 325 323 323 PRO PRO A . n A 1 326 ILE 326 324 324 ILE ILE A . n A 1 327 SER 327 325 325 SER SER A . n A 1 328 ASP 328 326 326 ASP ASP A . n A 1 329 PHE 329 327 327 PHE PHE A . n A 1 330 ALA 330 328 328 ALA ALA A . n A 1 331 SER 331 329 329 SER SER A . n A 1 332 TYR 332 330 330 TYR TYR A . n A 1 333 PHE 333 331 331 PHE PHE A . n A 1 334 GLN 334 332 332 GLN GLN A . n A 1 335 SER 335 333 333 SER SER A . n A 1 336 LEU 336 334 334 LEU LEU A . n A 1 337 ASP 337 335 335 ASP ASP A . n A 1 338 PRO 338 336 336 PRO PRO A . n A 1 339 TRP 339 337 337 TRP TRP A . n A 1 340 ASN 340 338 338 ASN ASN A . n A 1 341 ASN 341 339 339 ASN ASN A . n A 1 342 SER 342 340 340 SER SER A . n A 1 343 ARG 343 341 341 ARG ARG A . n A 1 344 ASN 344 342 342 ASN ASN A . n A 1 345 PRO 345 343 343 PRO PRO A . n A 1 346 TRP 346 344 344 TRP TRP A . n A 1 347 PHE 347 345 345 PHE PHE A . n A 1 348 ARG 348 346 346 ARG ARG A . n A 1 349 GLU 349 347 347 GLU GLU A . n A 1 350 PHE 350 348 348 PHE PHE A . n A 1 351 TRP 351 349 349 TRP TRP A . n A 1 352 GLU 352 350 350 GLU GLU A . n A 1 353 GLN 353 351 351 GLN GLN A . n A 1 354 ARG 354 352 352 ARG ARG A . n A 1 355 PHE 355 353 353 PHE PHE A . n A 1 356 ARG 356 354 354 ARG ARG A . n A 1 357 CYS 357 355 355 CYS CYS A . n A 1 358 SER 358 356 356 SER SER A . n A 1 359 PHE 359 357 357 PHE PHE A . n A 1 360 ARG 360 358 358 ARG ARG A . n A 1 361 GLN 361 359 ? ? ? A . n A 1 362 ARG 362 360 360 ARG ARG A . n A 1 363 ASP 363 361 361 ASP ASP A . n A 1 364 CYS 364 362 362 CYS CYS A . n A 1 365 ALA 365 363 363 ALA ALA A . n A 1 366 ALA 366 364 364 ALA ALA A . n A 1 367 HIS 367 365 365 HIS HIS A . n A 1 368 SER 368 366 366 SER SER A . n A 1 369 LEU 369 367 367 LEU LEU A . n A 1 370 ARG 370 368 368 ARG ARG A . n A 1 371 ALA 371 369 369 ALA ALA A . n A 1 372 VAL 372 370 370 VAL VAL A . n A 1 373 PRO 373 371 371 PRO PRO A . n A 1 374 PHE 374 372 372 PHE PHE A . n A 1 375 GLU 375 373 373 GLU GLU A . n A 1 376 GLN 376 374 374 GLN GLN A . n A 1 377 GLU 377 375 375 GLU GLU A . n A 1 378 SER 378 376 376 SER SER A . n A 1 379 LYS 379 377 377 LYS LYS A . n A 1 380 ILE 380 378 378 ILE ILE A . n A 1 381 MET 381 379 379 MET MET A . n A 1 382 PHE 382 380 380 PHE PHE A . n A 1 383 VAL 383 381 381 VAL VAL A . n A 1 384 VAL 384 382 382 VAL VAL A . n A 1 385 ASN 385 383 383 ASN ASN A . n A 1 386 ALA 386 384 384 ALA ALA A . n A 1 387 VAL 387 385 385 VAL VAL A . n A 1 388 TYR 388 386 386 TYR TYR A . n A 1 389 ALA 389 387 387 ALA ALA A . n A 1 390 MET 390 388 388 MET MET A . n A 1 391 ALA 391 389 389 ALA ALA A . n A 1 392 HIS 392 390 390 HIS HIS A . n A 1 393 ALA 393 391 391 ALA ALA A . n A 1 394 LEU 394 392 392 LEU LEU A . n A 1 395 HIS 395 393 393 HIS HIS A . n A 1 396 ASN 396 394 394 ASN ASN A . n A 1 397 MET 397 395 395 MET MET A . n A 1 398 HIS 398 396 396 HIS HIS A . n A 1 399 ARG 399 397 397 ARG ARG A . n A 1 400 ALA 400 398 398 ALA ALA A . n A 1 401 LEU 401 399 399 LEU LEU A . n A 1 402 CYS 402 400 400 CYS CYS A . n A 1 403 PRO 403 401 401 PRO PRO A . n A 1 404 ASN 404 402 402 ASN ASN A . n A 1 405 THR 405 403 403 THR THR A . n A 1 406 THR 406 404 404 THR THR A . n A 1 407 ARG 407 405 405 ARG ARG A . n A 1 408 LEU 408 406 406 LEU LEU A . n A 1 409 CYS 409 407 407 CYS CYS A . n A 1 410 ASP 410 408 408 ASP ASP A . n A 1 411 ALA 411 409 409 ALA ALA A . n A 1 412 MET 412 410 410 MET MET A . n A 1 413 ARG 413 411 411 ARG ARG A . n A 1 414 PRO 414 412 412 PRO PRO A . n A 1 415 VAL 415 413 413 VAL VAL A . n A 1 416 ASN 416 414 414 ASN ASN A . n A 1 417 GLY 417 415 415 GLY GLY A . n A 1 418 ARG 418 416 416 ARG ARG A . n A 1 419 ARG 419 417 417 ARG ARG A . n A 1 420 LEU 420 418 418 LEU LEU A . n A 1 421 TYR 421 419 419 TYR TYR A . n A 1 422 LYS 422 420 420 LYS LYS A . n A 1 423 ASP 423 421 421 ASP ASP A . n A 1 424 PHE 424 422 422 PHE PHE A . n A 1 425 VAL 425 423 423 VAL VAL A . n A 1 426 LEU 426 424 424 LEU LEU A . n A 1 427 ASN 427 425 425 ASN ASN A . n A 1 428 VAL 428 426 426 VAL VAL A . n A 1 429 LYS 429 427 427 LYS LYS A . n A 1 430 PHE 430 428 428 PHE PHE A . n A 1 431 ASP 431 429 429 ASP ASP A . n A 1 432 ALA 432 430 430 ALA ALA A . n A 1 433 PRO 433 431 431 PRO PRO A . n A 1 434 PHE 434 432 432 PHE PHE A . n A 1 435 ARG 435 433 433 ARG ARG A . n A 1 436 PRO 436 434 434 PRO PRO A . n A 1 437 ALA 437 435 435 ALA ALA A . n A 1 438 ASP 438 436 436 ASP ASP A . n A 1 439 THR 439 437 437 THR THR A . n A 1 440 HIS 440 438 438 HIS HIS A . n A 1 441 ASN 441 439 439 ASN ASN A . n A 1 442 GLU 442 440 440 GLU GLU A . n A 1 443 VAL 443 441 441 VAL VAL A . n A 1 444 ARG 444 442 442 ARG ARG A . n A 1 445 PHE 445 443 443 PHE PHE A . n A 1 446 ASP 446 444 444 ASP ASP A . n A 1 447 ARG 447 445 445 ARG ARG A . n A 1 448 PHE 448 446 446 PHE PHE A . n A 1 449 GLY 449 447 447 GLY GLY A . n A 1 450 ASP 450 448 448 ASP ASP A . n A 1 451 GLY 451 449 449 GLY GLY A . n A 1 452 ILE 452 450 450 ILE ILE A . n A 1 453 GLY 453 451 451 GLY GLY A . n A 1 454 ARG 454 452 452 ARG ARG A . n A 1 455 TYR 455 453 453 TYR TYR A . n A 1 456 ASN 456 454 454 ASN ASN A . n A 1 457 ILE 457 455 455 ILE ILE A . n A 1 458 PHE 458 456 456 PHE PHE A . n A 1 459 THR 459 457 457 THR THR A . n A 1 460 TYR 460 458 458 TYR TYR A . n A 1 461 LEU 461 459 459 LEU LEU A . n A 1 462 ARG 462 460 460 ARG ARG A . n A 1 463 ALA 463 461 461 ALA ALA A . n A 1 464 GLY 464 462 ? ? ? A . n A 1 465 SER 465 463 ? ? ? A . n A 1 466 GLY 466 464 464 GLY GLY A . n A 1 467 ARG 467 465 465 ARG ARG A . n A 1 468 TYR 468 466 466 TYR TYR A . n A 1 469 ARG 469 467 467 ARG ARG A . n A 1 470 TYR 470 468 468 TYR TYR A . n A 1 471 GLN 471 469 469 GLN GLN A . n A 1 472 LYS 472 470 470 LYS LYS A . n A 1 473 VAL 473 471 471 VAL VAL A . n A 1 474 GLY 474 472 472 GLY GLY A . n A 1 475 TYR 475 473 473 TYR TYR A . n A 1 476 TRP 476 474 474 TRP TRP A . n A 1 477 ALA 477 475 475 ALA ALA A . n A 1 478 GLU 478 476 476 GLU GLU A . n A 1 479 GLY 479 477 477 GLY GLY A . n A 1 480 LEU 480 478 478 LEU LEU A . n A 1 481 THR 481 479 479 THR THR A . n A 1 482 LEU 482 480 480 LEU LEU A . n A 1 483 ASP 483 481 481 ASP ASP A . n A 1 484 THR 484 482 482 THR THR A . n A 1 485 SER 485 483 483 SER SER A . n A 1 486 LEU 486 484 484 LEU LEU A . n A 1 487 ILE 487 485 485 ILE ILE A . n A 1 488 PRO 488 486 486 PRO PRO A . n A 1 489 TRP 489 487 487 TRP TRP A . n A 1 490 ALA 490 488 ? ? ? A . n A 1 491 SER 491 489 ? ? ? A . n A 1 492 PRO 492 490 ? ? ? A . n A 1 493 SER 493 491 ? ? ? A . n A 1 494 ALA 494 492 ? ? ? A . n A 1 495 GLY 495 493 ? ? ? A . n A 1 496 GLU 496 494 ? ? ? A . n A 1 497 GLY 497 495 ? ? ? A . n A 1 498 HIS 498 496 ? ? ? A . n A 1 499 HIS 499 497 ? ? ? A . n A 1 500 HIS 500 498 ? ? ? A . n A 1 501 HIS 501 499 ? ? ? A . n A 1 502 HIS 502 500 ? ? ? A . n A 1 503 HIS 503 501 ? ? ? A . n B 1 1 MET 1 -1 ? ? ? B . n B 1 2 ALA 2 0 ? ? ? B . n B 1 3 LEU 3 1 ? ? ? B . n B 1 4 GLY 4 2 ? ? ? B . n B 1 5 SER 5 3 ? ? ? B . n B 1 6 LEU 6 4 ? ? ? B . n B 1 7 LEU 7 5 ? ? ? B . n B 1 8 ALA 8 6 ? ? ? B . n B 1 9 LEU 9 7 ? ? ? B . n B 1 10 LEU 10 8 ? ? ? B . n B 1 11 ALA 11 9 ? ? ? B . n B 1 12 LEU 12 10 ? ? ? B . n B 1 13 LEU 13 11 ? ? ? B . n B 1 14 LEU 14 12 ? ? ? B . n B 1 15 LEU 15 13 ? ? ? B . n B 1 16 TRP 16 14 ? ? ? B . n B 1 17 GLY 17 15 ? ? ? B . n B 1 18 ALA 18 16 ? ? ? B . n B 1 19 VAL 19 17 ? ? ? B . n B 1 20 ALA 20 18 ? ? ? B . n B 1 21 GLU 21 19 ? ? ? B . n B 1 22 GLY 22 20 ? ? ? B . n B 1 23 PRO 23 21 ? ? ? B . n B 1 24 ALA 24 22 ? ? ? B . n B 1 25 LYS 25 23 23 LYS LYS B . n B 1 26 LYS 26 24 24 LYS LYS B . n B 1 27 VAL 27 25 25 VAL VAL B . n B 1 28 LEU 28 26 26 LEU LEU B . n B 1 29 THR 29 27 27 THR THR B . n B 1 30 LEU 30 28 28 LEU LEU B . n B 1 31 GLU 31 29 29 GLU GLU B . n B 1 32 GLY 32 30 30 GLY GLY B . n B 1 33 ASP 33 31 31 ASP ASP B . n B 1 34 LEU 34 32 32 LEU LEU B . n B 1 35 VAL 35 33 33 VAL VAL B . n B 1 36 LEU 36 34 34 LEU LEU B . n B 1 37 GLY 37 35 35 GLY GLY B . n B 1 38 GLY 38 36 36 GLY GLY B . n B 1 39 LEU 39 37 37 LEU LEU B . n B 1 40 PHE 40 38 38 PHE PHE B . n B 1 41 PRO 41 39 39 PRO PRO B . n B 1 42 VAL 42 40 40 VAL VAL B . n B 1 43 HIS 43 41 41 HIS HIS B . n B 1 44 GLN 44 42 42 GLN GLN B . n B 1 45 LYS 45 43 43 LYS LYS B . n B 1 46 GLY 46 44 44 GLY GLY B . n B 1 47 GLY 47 45 45 GLY GLY B . n B 1 48 PRO 48 46 46 PRO PRO B . n B 1 49 ALA 49 47 47 ALA ALA B . n B 1 50 GLU 50 48 48 GLU GLU B . n B 1 51 ASP 51 49 49 ASP ASP B . n B 1 52 CYS 52 50 50 CYS CYS B . n B 1 53 GLY 53 51 51 GLY GLY B . n B 1 54 PRO 54 52 52 PRO PRO B . n B 1 55 VAL 55 53 53 VAL VAL B . n B 1 56 ASN 56 54 54 ASN ASN B . n B 1 57 GLU 57 55 55 GLU GLU B . n B 1 58 HIS 58 56 56 HIS HIS B . n B 1 59 ARG 59 57 57 ARG ARG B . n B 1 60 GLY 60 58 58 GLY GLY B . n B 1 61 ILE 61 59 59 ILE ILE B . n B 1 62 GLN 62 60 60 GLN GLN B . n B 1 63 ARG 63 61 61 ARG ARG B . n B 1 64 LEU 64 62 62 LEU LEU B . n B 1 65 GLU 65 63 63 GLU GLU B . n B 1 66 ALA 66 64 64 ALA ALA B . n B 1 67 MET 67 65 65 MET MET B . n B 1 68 LEU 68 66 66 LEU LEU B . n B 1 69 PHE 69 67 67 PHE PHE B . n B 1 70 ALA 70 68 68 ALA ALA B . n B 1 71 LEU 71 69 69 LEU LEU B . n B 1 72 ASP 72 70 70 ASP ASP B . n B 1 73 ARG 73 71 71 ARG ARG B . n B 1 74 ILE 74 72 72 ILE ILE B . n B 1 75 ASN 75 73 73 ASN ASN B . n B 1 76 ARG 76 74 74 ARG ARG B . n B 1 77 ASP 77 75 75 ASP ASP B . n B 1 78 PRO 78 76 76 PRO PRO B . n B 1 79 HIS 79 77 77 HIS HIS B . n B 1 80 LEU 80 78 78 LEU LEU B . n B 1 81 LEU 81 79 79 LEU LEU B . n B 1 82 PRO 82 80 80 PRO PRO B . n B 1 83 GLY 83 81 81 GLY GLY B . n B 1 84 VAL 84 82 82 VAL VAL B . n B 1 85 ARG 85 83 83 ARG ARG B . n B 1 86 LEU 86 84 84 LEU LEU B . n B 1 87 GLY 87 85 85 GLY GLY B . n B 1 88 ALA 88 86 86 ALA ALA B . n B 1 89 HIS 89 87 87 HIS HIS B . n B 1 90 ILE 90 88 88 ILE ILE B . n B 1 91 LEU 91 89 89 LEU LEU B . n B 1 92 ASP 92 90 90 ASP ASP B . n B 1 93 SER 93 91 91 SER SER B . n B 1 94 CYS 94 92 92 CYS CYS B . n B 1 95 SER 95 93 93 SER SER B . n B 1 96 LYS 96 94 94 LYS LYS B . n B 1 97 ASP 97 95 95 ASP ASP B . n B 1 98 THR 98 96 96 THR THR B . n B 1 99 HIS 99 97 97 HIS HIS B . n B 1 100 ALA 100 98 98 ALA ALA B . n B 1 101 LEU 101 99 99 LEU LEU B . n B 1 102 GLU 102 100 100 GLU GLU B . n B 1 103 GLN 103 101 101 GLN GLN B . n B 1 104 ALA 104 102 102 ALA ALA B . n B 1 105 LEU 105 103 103 LEU LEU B . n B 1 106 ASP 106 104 104 ASP ASP B . n B 1 107 PHE 107 105 105 PHE PHE B . n B 1 108 VAL 108 106 106 VAL VAL B . n B 1 109 ARG 109 107 107 ARG ARG B . n B 1 110 ALA 110 108 108 ALA ALA B . n B 1 111 SER 111 109 109 SER SER B . n B 1 112 LEU 112 110 ? ? ? B . n B 1 113 SER 113 111 ? ? ? B . n B 1 114 ARG 114 112 ? ? ? B . n B 1 115 GLY 115 113 ? ? ? B . n B 1 116 ALA 116 114 ? ? ? B . n B 1 117 ASP 117 115 ? ? ? B . n B 1 118 GLY 118 116 ? ? ? B . n B 1 119 SER 119 117 ? ? ? B . n B 1 120 ARG 120 118 ? ? ? B . n B 1 121 HIS 121 119 ? ? ? B . n B 1 122 ILE 122 120 ? ? ? B . n B 1 123 CYS 123 121 ? ? ? B . n B 1 124 PRO 124 122 ? ? ? B . n B 1 125 ASP 125 123 ? ? ? B . n B 1 126 GLY 126 124 ? ? ? B . n B 1 127 SER 127 125 ? ? ? B . n B 1 128 TYR 128 126 ? ? ? B . n B 1 129 ALA 129 127 ? ? ? B . n B 1 130 THR 130 128 ? ? ? B . n B 1 131 HIS 131 129 ? ? ? B . n B 1 132 GLY 132 130 ? ? ? B . n B 1 133 ASP 133 131 ? ? ? B . n B 1 134 ALA 134 132 ? ? ? B . n B 1 135 PRO 135 133 ? ? ? B . n B 1 136 THR 136 134 134 THR THR B . n B 1 137 ALA 137 135 135 ALA ALA B . n B 1 138 ILE 138 136 136 ILE ILE B . n B 1 139 THR 139 137 137 THR THR B . n B 1 140 GLY 140 138 138 GLY GLY B . n B 1 141 VAL 141 139 139 VAL VAL B . n B 1 142 ILE 142 140 140 ILE ILE B . n B 1 143 GLY 143 141 141 GLY GLY B . n B 1 144 GLY 144 142 142 GLY GLY B . n B 1 145 SER 145 143 143 SER SER B . n B 1 146 TYR 146 144 144 TYR TYR B . n B 1 147 SER 147 145 145 SER SER B . n B 1 148 ASP 148 146 146 ASP ASP B . n B 1 149 VAL 149 147 147 VAL VAL B . n B 1 150 SER 150 148 148 SER SER B . n B 1 151 ILE 151 149 149 ILE ILE B . n B 1 152 GLN 152 150 150 GLN GLN B . n B 1 153 VAL 153 151 151 VAL VAL B . n B 1 154 ALA 154 152 152 ALA ALA B . n B 1 155 ASN 155 153 153 ASN ASN B . n B 1 156 LEU 156 154 154 LEU LEU B . n B 1 157 LEU 157 155 155 LEU LEU B . n B 1 158 ARG 158 156 156 ARG ARG B . n B 1 159 LEU 159 157 157 LEU LEU B . n B 1 160 PHE 160 158 158 PHE PHE B . n B 1 161 GLN 161 159 159 GLN GLN B . n B 1 162 ILE 162 160 160 ILE ILE B . n B 1 163 PRO 163 161 161 PRO PRO B . n B 1 164 GLN 164 162 162 GLN GLN B . n B 1 165 ILE 165 163 163 ILE ILE B . n B 1 166 SER 166 164 164 SER SER B . n B 1 167 TYR 167 165 165 TYR TYR B . n B 1 168 ALA 168 166 166 ALA ALA B . n B 1 169 SER 169 167 167 SER SER B . n B 1 170 THR 170 168 168 THR THR B . n B 1 171 SER 171 169 169 SER SER B . n B 1 172 ALA 172 170 170 ALA ALA B . n B 1 173 LYS 173 171 171 LYS LYS B . n B 1 174 LEU 174 172 172 LEU LEU B . n B 1 175 SER 175 173 173 SER SER B . n B 1 176 ASP 176 174 174 ASP ASP B . n B 1 177 LYS 177 175 175 LYS LYS B . n B 1 178 SER 178 176 176 SER SER B . n B 1 179 ARG 179 177 177 ARG ARG B . n B 1 180 TYR 180 178 178 TYR TYR B . n B 1 181 ASP 181 179 179 ASP ASP B . n B 1 182 TYR 182 180 180 TYR TYR B . n B 1 183 PHE 183 181 181 PHE PHE B . n B 1 184 ALA 184 182 182 ALA ALA B . n B 1 185 ARG 185 183 183 ARG ARG B . n B 1 186 THR 186 184 184 THR THR B . n B 1 187 VAL 187 185 185 VAL VAL B . n B 1 188 PRO 188 186 186 PRO PRO B . n B 1 189 PRO 189 187 187 PRO PRO B . n B 1 190 ASP 190 188 188 ASP ASP B . n B 1 191 PHE 191 189 189 PHE PHE B . n B 1 192 PHE 192 190 190 PHE PHE B . n B 1 193 GLN 193 191 191 GLN GLN B . n B 1 194 ALA 194 192 192 ALA ALA B . n B 1 195 LYS 195 193 193 LYS LYS B . n B 1 196 ALA 196 194 194 ALA ALA B . n B 1 197 MET 197 195 195 MET MET B . n B 1 198 ALA 198 196 196 ALA ALA B . n B 1 199 GLU 199 197 197 GLU GLU B . n B 1 200 ILE 200 198 198 ILE ILE B . n B 1 201 LEU 201 199 199 LEU LEU B . n B 1 202 ARG 202 200 200 ARG ARG B . n B 1 203 PHE 203 201 201 PHE PHE B . n B 1 204 PHE 204 202 202 PHE PHE B . n B 1 205 ASN 205 203 203 ASN ASN B . n B 1 206 TRP 206 204 204 TRP TRP B . n B 1 207 THR 207 205 205 THR THR B . n B 1 208 TYR 208 206 206 TYR TYR B . n B 1 209 VAL 209 207 207 VAL VAL B . n B 1 210 SER 210 208 208 SER SER B . n B 1 211 THR 211 209 209 THR THR B . n B 1 212 VAL 212 210 210 VAL VAL B . n B 1 213 ALA 213 211 211 ALA ALA B . n B 1 214 SER 214 212 212 SER SER B . n B 1 215 GLU 215 213 213 GLU GLU B . n B 1 216 GLY 216 214 214 GLY GLY B . n B 1 217 ASP 217 215 215 ASP ASP B . n B 1 218 TYR 218 216 216 TYR TYR B . n B 1 219 GLY 219 217 217 GLY GLY B . n B 1 220 GLU 220 218 218 GLU GLU B . n B 1 221 THR 221 219 219 THR THR B . n B 1 222 GLY 222 220 220 GLY GLY B . n B 1 223 ILE 223 221 221 ILE ILE B . n B 1 224 GLU 224 222 222 GLU GLU B . n B 1 225 ALA 225 223 223 ALA ALA B . n B 1 226 PHE 226 224 224 PHE PHE B . n B 1 227 GLU 227 225 225 GLU GLU B . n B 1 228 LEU 228 226 226 LEU LEU B . n B 1 229 GLU 229 227 227 GLU GLU B . n B 1 230 ALA 230 228 228 ALA ALA B . n B 1 231 ARG 231 229 229 ARG ARG B . n B 1 232 ALA 232 230 230 ALA ALA B . n B 1 233 ARG 233 231 231 ARG ARG B . n B 1 234 ASN 234 232 232 ASN ASN B . n B 1 235 ILE 235 233 233 ILE ILE B . n B 1 236 SER 236 234 234 SER SER B . n B 1 237 VAL 237 235 235 VAL VAL B . n B 1 238 ALA 238 236 236 ALA ALA B . n B 1 239 THR 239 237 237 THR THR B . n B 1 240 SER 240 238 238 SER SER B . n B 1 241 GLU 241 239 239 GLU GLU B . n B 1 242 LYS 242 240 240 LYS LYS B . n B 1 243 VAL 243 241 241 VAL VAL B . n B 1 244 GLY 244 242 242 GLY GLY B . n B 1 245 ARG 245 243 243 ARG ARG B . n B 1 246 ALA 246 244 244 ALA ALA B . n B 1 247 MET 247 245 245 MET MET B . n B 1 248 SER 248 246 246 SER SER B . n B 1 249 ARG 249 247 247 ARG ARG B . n B 1 250 ALA 250 248 248 ALA ALA B . n B 1 251 ALA 251 249 249 ALA ALA B . n B 1 252 PHE 252 250 250 PHE PHE B . n B 1 253 GLU 253 251 251 GLU GLU B . n B 1 254 GLY 254 252 252 GLY GLY B . n B 1 255 VAL 255 253 253 VAL VAL B . n B 1 256 VAL 256 254 254 VAL VAL B . n B 1 257 ARG 257 255 255 ARG ARG B . n B 1 258 ALA 258 256 256 ALA ALA B . n B 1 259 LEU 259 257 257 LEU LEU B . n B 1 260 LEU 260 258 258 LEU LEU B . n B 1 261 GLN 261 259 259 GLN GLN B . n B 1 262 LYS 262 260 260 LYS LYS B . n B 1 263 PRO 263 261 261 PRO PRO B . n B 1 264 SER 264 262 262 SER SER B . n B 1 265 ALA 265 263 263 ALA ALA B . n B 1 266 ARG 266 264 264 ARG ARG B . n B 1 267 VAL 267 265 265 VAL VAL B . n B 1 268 ALA 268 266 266 ALA ALA B . n B 1 269 VAL 269 267 267 VAL VAL B . n B 1 270 LEU 270 268 268 LEU LEU B . n B 1 271 PHE 271 269 269 PHE PHE B . n B 1 272 THR 272 270 270 THR THR B . n B 1 273 ARG 273 271 271 ARG ARG B . n B 1 274 SER 274 272 272 SER SER B . n B 1 275 GLU 275 273 273 GLU GLU B . n B 1 276 ASP 276 274 274 ASP ASP B . n B 1 277 ALA 277 275 275 ALA ALA B . n B 1 278 ARG 278 276 276 ARG ARG B . n B 1 279 GLU 279 277 277 GLU GLU B . n B 1 280 LEU 280 278 278 LEU LEU B . n B 1 281 LEU 281 279 279 LEU LEU B . n B 1 282 ALA 282 280 280 ALA ALA B . n B 1 283 ALA 283 281 281 ALA ALA B . n B 1 284 SER 284 282 282 SER SER B . n B 1 285 GLN 285 283 283 GLN GLN B . n B 1 286 ARG 286 284 284 ARG ARG B . n B 1 287 LEU 287 285 285 LEU LEU B . n B 1 288 ASN 288 286 286 ASN ASN B . n B 1 289 ALA 289 287 287 ALA ALA B . n B 1 290 SER 290 288 288 SER SER B . n B 1 291 PHE 291 289 289 PHE PHE B . n B 1 292 THR 292 290 290 THR THR B . n B 1 293 TRP 293 291 291 TRP TRP B . n B 1 294 VAL 294 292 292 VAL VAL B . n B 1 295 ALA 295 293 293 ALA ALA B . n B 1 296 SER 296 294 294 SER SER B . n B 1 297 ASP 297 295 295 ASP ASP B . n B 1 298 GLY 298 296 296 GLY GLY B . n B 1 299 TRP 299 297 297 TRP TRP B . n B 1 300 GLY 300 298 298 GLY GLY B . n B 1 301 ALA 301 299 299 ALA ALA B . n B 1 302 LEU 302 300 300 LEU LEU B . n B 1 303 GLU 303 301 301 GLU GLU B . n B 1 304 GLU 304 302 302 GLU GLU B . n B 1 305 VAL 305 303 303 VAL VAL B . n B 1 306 VAL 306 304 304 VAL VAL B . n B 1 307 ALA 307 305 305 ALA ALA B . n B 1 308 GLY 308 306 306 GLY GLY B . n B 1 309 SER 309 307 307 SER SER B . n B 1 310 GLU 310 308 308 GLU GLU B . n B 1 311 GLY 311 309 309 GLY GLY B . n B 1 312 ALA 312 310 310 ALA ALA B . n B 1 313 ALA 313 311 311 ALA ALA B . n B 1 314 GLU 314 312 312 GLU GLU B . n B 1 315 GLY 315 313 313 GLY GLY B . n B 1 316 ALA 316 314 314 ALA ALA B . n B 1 317 ILE 317 315 315 ILE ILE B . n B 1 318 THR 318 316 316 THR THR B . n B 1 319 ILE 319 317 317 ILE ILE B . n B 1 320 GLU 320 318 318 GLU GLU B . n B 1 321 LEU 321 319 319 LEU LEU B . n B 1 322 ALA 322 320 320 ALA ALA B . n B 1 323 SER 323 321 321 SER SER B . n B 1 324 TYR 324 322 322 TYR TYR B . n B 1 325 PRO 325 323 323 PRO PRO B . n B 1 326 ILE 326 324 324 ILE ILE B . n B 1 327 SER 327 325 325 SER SER B . n B 1 328 ASP 328 326 326 ASP ASP B . n B 1 329 PHE 329 327 327 PHE PHE B . n B 1 330 ALA 330 328 328 ALA ALA B . n B 1 331 SER 331 329 329 SER SER B . n B 1 332 TYR 332 330 330 TYR TYR B . n B 1 333 PHE 333 331 331 PHE PHE B . n B 1 334 GLN 334 332 332 GLN GLN B . n B 1 335 SER 335 333 333 SER SER B . n B 1 336 LEU 336 334 334 LEU LEU B . n B 1 337 ASP 337 335 335 ASP ASP B . n B 1 338 PRO 338 336 336 PRO PRO B . n B 1 339 TRP 339 337 337 TRP TRP B . n B 1 340 ASN 340 338 338 ASN ASN B . n B 1 341 ASN 341 339 339 ASN ASN B . n B 1 342 SER 342 340 340 SER SER B . n B 1 343 ARG 343 341 341 ARG ARG B . n B 1 344 ASN 344 342 342 ASN ASN B . n B 1 345 PRO 345 343 343 PRO PRO B . n B 1 346 TRP 346 344 344 TRP TRP B . n B 1 347 PHE 347 345 345 PHE PHE B . n B 1 348 ARG 348 346 346 ARG ARG B . n B 1 349 GLU 349 347 347 GLU GLU B . n B 1 350 PHE 350 348 348 PHE PHE B . n B 1 351 TRP 351 349 349 TRP TRP B . n B 1 352 GLU 352 350 350 GLU GLU B . n B 1 353 GLN 353 351 351 GLN GLN B . n B 1 354 ARG 354 352 352 ARG ARG B . n B 1 355 PHE 355 353 353 PHE PHE B . n B 1 356 ARG 356 354 354 ARG ARG B . n B 1 357 CYS 357 355 355 CYS CYS B . n B 1 358 SER 358 356 356 SER SER B . n B 1 359 PHE 359 357 357 PHE PHE B . n B 1 360 ARG 360 358 358 ARG ARG B . n B 1 361 GLN 361 359 359 GLN GLN B . n B 1 362 ARG 362 360 360 ARG ARG B . n B 1 363 ASP 363 361 361 ASP ASP B . n B 1 364 CYS 364 362 362 CYS CYS B . n B 1 365 ALA 365 363 363 ALA ALA B . n B 1 366 ALA 366 364 364 ALA ALA B . n B 1 367 HIS 367 365 365 HIS HIS B . n B 1 368 SER 368 366 366 SER SER B . n B 1 369 LEU 369 367 367 LEU LEU B . n B 1 370 ARG 370 368 368 ARG ARG B . n B 1 371 ALA 371 369 369 ALA ALA B . n B 1 372 VAL 372 370 370 VAL VAL B . n B 1 373 PRO 373 371 371 PRO PRO B . n B 1 374 PHE 374 372 372 PHE PHE B . n B 1 375 GLU 375 373 373 GLU GLU B . n B 1 376 GLN 376 374 374 GLN GLN B . n B 1 377 GLU 377 375 375 GLU GLU B . n B 1 378 SER 378 376 376 SER SER B . n B 1 379 LYS 379 377 377 LYS LYS B . n B 1 380 ILE 380 378 378 ILE ILE B . n B 1 381 MET 381 379 379 MET MET B . n B 1 382 PHE 382 380 380 PHE PHE B . n B 1 383 VAL 383 381 381 VAL VAL B . n B 1 384 VAL 384 382 382 VAL VAL B . n B 1 385 ASN 385 383 383 ASN ASN B . n B 1 386 ALA 386 384 384 ALA ALA B . n B 1 387 VAL 387 385 385 VAL VAL B . n B 1 388 TYR 388 386 386 TYR TYR B . n B 1 389 ALA 389 387 387 ALA ALA B . n B 1 390 MET 390 388 388 MET MET B . n B 1 391 ALA 391 389 389 ALA ALA B . n B 1 392 HIS 392 390 390 HIS HIS B . n B 1 393 ALA 393 391 391 ALA ALA B . n B 1 394 LEU 394 392 392 LEU LEU B . n B 1 395 HIS 395 393 393 HIS HIS B . n B 1 396 ASN 396 394 394 ASN ASN B . n B 1 397 MET 397 395 395 MET MET B . n B 1 398 HIS 398 396 396 HIS HIS B . n B 1 399 ARG 399 397 397 ARG ARG B . n B 1 400 ALA 400 398 398 ALA ALA B . n B 1 401 LEU 401 399 399 LEU LEU B . n B 1 402 CYS 402 400 400 CYS CYS B . n B 1 403 PRO 403 401 401 PRO PRO B . n B 1 404 ASN 404 402 402 ASN ASN B . n B 1 405 THR 405 403 403 THR THR B . n B 1 406 THR 406 404 404 THR THR B . n B 1 407 ARG 407 405 405 ARG ARG B . n B 1 408 LEU 408 406 406 LEU LEU B . n B 1 409 CYS 409 407 407 CYS CYS B . n B 1 410 ASP 410 408 408 ASP ASP B . n B 1 411 ALA 411 409 409 ALA ALA B . n B 1 412 MET 412 410 410 MET MET B . n B 1 413 ARG 413 411 411 ARG ARG B . n B 1 414 PRO 414 412 412 PRO PRO B . n B 1 415 VAL 415 413 413 VAL VAL B . n B 1 416 ASN 416 414 414 ASN ASN B . n B 1 417 GLY 417 415 415 GLY GLY B . n B 1 418 ARG 418 416 416 ARG ARG B . n B 1 419 ARG 419 417 417 ARG ARG B . n B 1 420 LEU 420 418 418 LEU LEU B . n B 1 421 TYR 421 419 419 TYR TYR B . n B 1 422 LYS 422 420 420 LYS LYS B . n B 1 423 ASP 423 421 421 ASP ASP B . n B 1 424 PHE 424 422 422 PHE PHE B . n B 1 425 VAL 425 423 423 VAL VAL B . n B 1 426 LEU 426 424 424 LEU LEU B . n B 1 427 ASN 427 425 425 ASN ASN B . n B 1 428 VAL 428 426 426 VAL VAL B . n B 1 429 LYS 429 427 427 LYS LYS B . n B 1 430 PHE 430 428 428 PHE PHE B . n B 1 431 ASP 431 429 429 ASP ASP B . n B 1 432 ALA 432 430 430 ALA ALA B . n B 1 433 PRO 433 431 431 PRO PRO B . n B 1 434 PHE 434 432 432 PHE PHE B . n B 1 435 ARG 435 433 ? ? ? B . n B 1 436 PRO 436 434 ? ? ? B . n B 1 437 ALA 437 435 435 ALA ALA B . n B 1 438 ASP 438 436 436 ASP ASP B . n B 1 439 THR 439 437 437 THR THR B . n B 1 440 HIS 440 438 438 HIS HIS B . n B 1 441 ASN 441 439 439 ASN ASN B . n B 1 442 GLU 442 440 440 GLU GLU B . n B 1 443 VAL 443 441 441 VAL VAL B . n B 1 444 ARG 444 442 442 ARG ARG B . n B 1 445 PHE 445 443 443 PHE PHE B . n B 1 446 ASP 446 444 444 ASP ASP B . n B 1 447 ARG 447 445 445 ARG ARG B . n B 1 448 PHE 448 446 446 PHE PHE B . n B 1 449 GLY 449 447 447 GLY GLY B . n B 1 450 ASP 450 448 448 ASP ASP B . n B 1 451 GLY 451 449 449 GLY GLY B . n B 1 452 ILE 452 450 450 ILE ILE B . n B 1 453 GLY 453 451 451 GLY GLY B . n B 1 454 ARG 454 452 452 ARG ARG B . n B 1 455 TYR 455 453 453 TYR TYR B . n B 1 456 ASN 456 454 454 ASN ASN B . n B 1 457 ILE 457 455 455 ILE ILE B . n B 1 458 PHE 458 456 456 PHE PHE B . n B 1 459 THR 459 457 457 THR THR B . n B 1 460 TYR 460 458 458 TYR TYR B . n B 1 461 LEU 461 459 459 LEU LEU B . n B 1 462 ARG 462 460 460 ARG ARG B . n B 1 463 ALA 463 461 461 ALA ALA B . n B 1 464 GLY 464 462 462 GLY GLY B . n B 1 465 SER 465 463 ? ? ? B . n B 1 466 GLY 466 464 464 GLY GLY B . n B 1 467 ARG 467 465 465 ARG ARG B . n B 1 468 TYR 468 466 466 TYR TYR B . n B 1 469 ARG 469 467 467 ARG ARG B . n B 1 470 TYR 470 468 468 TYR TYR B . n B 1 471 GLN 471 469 469 GLN GLN B . n B 1 472 LYS 472 470 470 LYS LYS B . n B 1 473 VAL 473 471 471 VAL VAL B . n B 1 474 GLY 474 472 472 GLY GLY B . n B 1 475 TYR 475 473 473 TYR TYR B . n B 1 476 TRP 476 474 474 TRP TRP B . n B 1 477 ALA 477 475 475 ALA ALA B . n B 1 478 GLU 478 476 476 GLU GLU B . n B 1 479 GLY 479 477 477 GLY GLY B . n B 1 480 LEU 480 478 478 LEU LEU B . n B 1 481 THR 481 479 479 THR THR B . n B 1 482 LEU 482 480 480 LEU LEU B . n B 1 483 ASP 483 481 481 ASP ASP B . n B 1 484 THR 484 482 482 THR THR B . n B 1 485 SER 485 483 483 SER SER B . n B 1 486 LEU 486 484 484 LEU LEU B . n B 1 487 ILE 487 485 485 ILE ILE B . n B 1 488 PRO 488 486 486 PRO PRO B . n B 1 489 TRP 489 487 487 TRP TRP B . n B 1 490 ALA 490 488 ? ? ? B . n B 1 491 SER 491 489 ? ? ? B . n B 1 492 PRO 492 490 ? ? ? B . n B 1 493 SER 493 491 ? ? ? B . n B 1 494 ALA 494 492 ? ? ? B . n B 1 495 GLY 495 493 ? ? ? B . n B 1 496 GLU 496 494 ? ? ? B . n B 1 497 GLY 497 495 ? ? ? B . n B 1 498 HIS 498 496 ? ? ? B . n B 1 499 HIS 499 497 ? ? ? B . n B 1 500 HIS 500 498 ? ? ? B . n B 1 501 HIS 501 499 ? ? ? B . n B 1 502 HIS 502 500 ? ? ? B . n B 1 503 HIS 503 501 ? ? ? B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 GGL 1 601 1 GGL SX1 A . D 3 CL 1 602 2 CL CL A . E 4 NA 1 603 3 NA NA A . F 5 NAG 1 604 3 NAG NAG A . G 5 NAG 1 605 4 NAG NAG A . H 2 GGL 1 601 2 GGL SX1 B . I 3 CL 1 602 1 CL CL B . J 4 NA 1 603 4 NA NA B . K 5 NAG 1 604 5 NAG NAG B . L 5 NAG 1 605 6 NAG NAG B . M 6 HOH 1 701 373 HOH HOH A . M 6 HOH 2 702 344 HOH HOH A . M 6 HOH 3 703 307 HOH HOH A . M 6 HOH 4 704 175 HOH HOH A . M 6 HOH 5 705 9 HOH HOH A . M 6 HOH 6 706 374 HOH HOH A . M 6 HOH 7 707 345 HOH HOH A . M 6 HOH 8 708 27 HOH HOH A . M 6 HOH 9 709 367 HOH HOH A . M 6 HOH 10 710 63 HOH HOH A . M 6 HOH 11 711 2 HOH HOH A . M 6 HOH 12 712 305 HOH HOH A . M 6 HOH 13 713 112 HOH HOH A . M 6 HOH 14 714 3 HOH HOH A . M 6 HOH 15 715 336 HOH HOH A . M 6 HOH 16 716 368 HOH HOH A . M 6 HOH 17 717 366 HOH HOH A . M 6 HOH 18 718 194 HOH HOH A . M 6 HOH 19 719 370 HOH HOH A . M 6 HOH 20 720 5 HOH HOH A . M 6 HOH 21 721 337 HOH HOH A . M 6 HOH 22 722 228 HOH HOH A . M 6 HOH 23 723 195 HOH HOH A . M 6 HOH 24 724 285 HOH HOH A . M 6 HOH 25 725 76 HOH HOH A . M 6 HOH 26 726 120 HOH HOH A . M 6 HOH 27 727 30 HOH HOH A . M 6 HOH 28 728 180 HOH HOH A . M 6 HOH 29 729 138 HOH HOH A . M 6 HOH 30 730 333 HOH HOH A . M 6 HOH 31 731 317 HOH HOH A . M 6 HOH 32 732 329 HOH HOH A . M 6 HOH 33 733 316 HOH HOH A . M 6 HOH 34 734 108 HOH HOH A . M 6 HOH 35 735 192 HOH HOH A . M 6 HOH 36 736 371 HOH HOH A . M 6 HOH 37 737 40 HOH HOH A . M 6 HOH 38 738 123 HOH HOH A . M 6 HOH 39 739 91 HOH HOH A . M 6 HOH 40 740 32 HOH HOH A . M 6 HOH 41 741 142 HOH HOH A . M 6 HOH 42 742 75 HOH HOH A . M 6 HOH 43 743 323 HOH HOH A . M 6 HOH 44 744 372 HOH HOH A . M 6 HOH 45 745 31 HOH HOH A . M 6 HOH 46 746 157 HOH HOH A . M 6 HOH 47 747 221 HOH HOH A . M 6 HOH 48 748 4 HOH HOH A . M 6 HOH 49 749 350 HOH HOH A . M 6 HOH 50 750 81 HOH HOH A . M 6 HOH 51 751 158 HOH HOH A . M 6 HOH 52 752 347 HOH HOH A . M 6 HOH 53 753 182 HOH HOH A . M 6 HOH 54 754 332 HOH HOH A . M 6 HOH 55 755 227 HOH HOH A . M 6 HOH 56 756 193 HOH HOH A . M 6 HOH 57 757 363 HOH HOH A . M 6 HOH 58 758 15 HOH HOH A . M 6 HOH 59 759 136 HOH HOH A . M 6 HOH 60 760 216 HOH HOH A . M 6 HOH 61 761 191 HOH HOH A . M 6 HOH 62 762 335 HOH HOH A . M 6 HOH 63 763 257 HOH HOH A . M 6 HOH 64 764 20 HOH HOH A . M 6 HOH 65 765 375 HOH HOH A . M 6 HOH 66 766 106 HOH HOH A . M 6 HOH 67 767 154 HOH HOH A . M 6 HOH 68 768 113 HOH HOH A . M 6 HOH 69 769 348 HOH HOH A . M 6 HOH 70 770 197 HOH HOH A . M 6 HOH 71 771 319 HOH HOH A . M 6 HOH 72 772 122 HOH HOH A . M 6 HOH 73 773 68 HOH HOH A . M 6 HOH 74 774 53 HOH HOH A . M 6 HOH 75 775 131 HOH HOH A . M 6 HOH 76 776 16 HOH HOH A . M 6 HOH 77 777 238 HOH HOH A . M 6 HOH 78 778 23 HOH HOH A . M 6 HOH 79 779 148 HOH HOH A . M 6 HOH 80 780 37 HOH HOH A . M 6 HOH 81 781 261 HOH HOH A . M 6 HOH 82 782 177 HOH HOH A . M 6 HOH 83 783 342 HOH HOH A . M 6 HOH 84 784 58 HOH HOH A . M 6 HOH 85 785 21 HOH HOH A . M 6 HOH 86 786 231 HOH HOH A . M 6 HOH 87 787 77 HOH HOH A . M 6 HOH 88 788 41 HOH HOH A . M 6 HOH 89 789 364 HOH HOH A . M 6 HOH 90 790 159 HOH HOH A . M 6 HOH 91 791 272 HOH HOH A . M 6 HOH 92 792 349 HOH HOH A . M 6 HOH 93 793 249 HOH HOH A . M 6 HOH 94 794 301 HOH HOH A . M 6 HOH 95 795 117 HOH HOH A . M 6 HOH 96 796 88 HOH HOH A . M 6 HOH 97 797 369 HOH HOH A . M 6 HOH 98 798 100 HOH HOH A . M 6 HOH 99 799 340 HOH HOH A . M 6 HOH 100 800 129 HOH HOH A . M 6 HOH 101 801 302 HOH HOH A . M 6 HOH 102 802 176 HOH HOH A . M 6 HOH 103 803 188 HOH HOH A . M 6 HOH 104 804 24 HOH HOH A . M 6 HOH 105 805 276 HOH HOH A . M 6 HOH 106 806 114 HOH HOH A . M 6 HOH 107 807 358 HOH HOH A . M 6 HOH 108 808 36 HOH HOH A . M 6 HOH 109 809 140 HOH HOH A . M 6 HOH 110 810 198 HOH HOH A . M 6 HOH 111 811 234 HOH HOH A . M 6 HOH 112 812 346 HOH HOH A . M 6 HOH 113 813 161 HOH HOH A . M 6 HOH 114 814 343 HOH HOH A . M 6 HOH 115 815 163 HOH HOH A . M 6 HOH 116 816 362 HOH HOH A . M 6 HOH 117 817 57 HOH HOH A . M 6 HOH 118 818 341 HOH HOH A . M 6 HOH 119 819 281 HOH HOH A . M 6 HOH 120 820 296 HOH HOH A . N 6 HOH 1 701 378 HOH HOH B . N 6 HOH 2 702 365 HOH HOH B . N 6 HOH 3 703 355 HOH HOH B . N 6 HOH 4 704 215 HOH HOH B . N 6 HOH 5 705 178 HOH HOH B . N 6 HOH 6 706 232 HOH HOH B . N 6 HOH 7 707 22 HOH HOH B . N 6 HOH 8 708 172 HOH HOH B . N 6 HOH 9 709 71 HOH HOH B . N 6 HOH 10 710 164 HOH HOH B . N 6 HOH 11 711 179 HOH HOH B . N 6 HOH 12 712 26 HOH HOH B . N 6 HOH 13 713 383 HOH HOH B . N 6 HOH 14 714 171 HOH HOH B . N 6 HOH 15 715 320 HOH HOH B . N 6 HOH 16 716 356 HOH HOH B . N 6 HOH 17 717 89 HOH HOH B . N 6 HOH 18 718 62 HOH HOH B . N 6 HOH 19 719 352 HOH HOH B . N 6 HOH 20 720 359 HOH HOH B . N 6 HOH 21 721 376 HOH HOH B . N 6 HOH 22 722 354 HOH HOH B . N 6 HOH 23 723 321 HOH HOH B . N 6 HOH 24 724 328 HOH HOH B . N 6 HOH 25 725 69 HOH HOH B . N 6 HOH 26 726 244 HOH HOH B . N 6 HOH 27 727 239 HOH HOH B . N 6 HOH 28 728 72 HOH HOH B . N 6 HOH 29 729 380 HOH HOH B . N 6 HOH 30 730 48 HOH HOH B . N 6 HOH 31 731 8 HOH HOH B . N 6 HOH 32 732 44 HOH HOH B . N 6 HOH 33 733 25 HOH HOH B . N 6 HOH 34 734 351 HOH HOH B . N 6 HOH 35 735 381 HOH HOH B . N 6 HOH 36 736 14 HOH HOH B . N 6 HOH 37 737 303 HOH HOH B . N 6 HOH 38 738 326 HOH HOH B . N 6 HOH 39 739 322 HOH HOH B . N 6 HOH 40 740 42 HOH HOH B . N 6 HOH 41 741 334 HOH HOH B . N 6 HOH 42 742 318 HOH HOH B . N 6 HOH 43 743 300 HOH HOH B . N 6 HOH 44 744 382 HOH HOH B . N 6 HOH 45 745 39 HOH HOH B . N 6 HOH 46 746 101 HOH HOH B . N 6 HOH 47 747 167 HOH HOH B . N 6 HOH 48 748 162 HOH HOH B . N 6 HOH 49 749 246 HOH HOH B . N 6 HOH 50 750 379 HOH HOH B . N 6 HOH 51 751 82 HOH HOH B . N 6 HOH 52 752 47 HOH HOH B . N 6 HOH 53 753 306 HOH HOH B . N 6 HOH 54 754 104 HOH HOH B . N 6 HOH 55 755 168 HOH HOH B . N 6 HOH 56 756 377 HOH HOH B . N 6 HOH 57 757 304 HOH HOH B . N 6 HOH 58 758 173 HOH HOH B . N 6 HOH 59 759 12 HOH HOH B . N 6 HOH 60 760 205 HOH HOH B . N 6 HOH 61 761 220 HOH HOH B . N 6 HOH 62 762 313 HOH HOH B . N 6 HOH 63 763 132 HOH HOH B . N 6 HOH 64 764 165 HOH HOH B . N 6 HOH 65 765 18 HOH HOH B . N 6 HOH 66 766 46 HOH HOH B . N 6 HOH 67 767 59 HOH HOH B . N 6 HOH 68 768 1 HOH HOH B . N 6 HOH 69 769 357 HOH HOH B . N 6 HOH 70 770 35 HOH HOH B . N 6 HOH 71 771 29 HOH HOH B . N 6 HOH 72 772 125 HOH HOH B . N 6 HOH 73 773 109 HOH HOH B . N 6 HOH 74 774 99 HOH HOH B . N 6 HOH 75 775 258 HOH HOH B . N 6 HOH 76 776 80 HOH HOH B . N 6 HOH 77 777 218 HOH HOH B . N 6 HOH 78 778 210 HOH HOH B . N 6 HOH 79 779 170 HOH HOH B . N 6 HOH 80 780 248 HOH HOH B . N 6 HOH 81 781 7 HOH HOH B . N 6 HOH 82 782 10 HOH HOH B . N 6 HOH 83 783 233 HOH HOH B . N 6 HOH 84 784 353 HOH HOH B . N 6 HOH 85 785 13 HOH HOH B . N 6 HOH 86 786 87 HOH HOH B . N 6 HOH 87 787 49 HOH HOH B . N 6 HOH 88 788 103 HOH HOH B . N 6 HOH 89 789 339 HOH HOH B . N 6 HOH 90 790 127 HOH HOH B . N 6 HOH 91 791 19 HOH HOH B . N 6 HOH 92 792 133 HOH HOH B . N 6 HOH 93 793 331 HOH HOH B . N 6 HOH 94 794 211 HOH HOH B . N 6 HOH 95 795 55 HOH HOH B . N 6 HOH 96 796 111 HOH HOH B . N 6 HOH 97 797 166 HOH HOH B . N 6 HOH 98 798 43 HOH HOH B . N 6 HOH 99 799 52 HOH HOH B . N 6 HOH 100 800 181 HOH HOH B . N 6 HOH 101 801 338 HOH HOH B . N 6 HOH 102 802 223 HOH HOH B . N 6 HOH 103 803 264 HOH HOH B . N 6 HOH 104 804 67 HOH HOH B . N 6 HOH 105 805 174 HOH HOH B . N 6 HOH 106 806 34 HOH HOH B . N 6 HOH 107 807 119 HOH HOH B . N 6 HOH 108 808 262 HOH HOH B . N 6 HOH 109 809 209 HOH HOH B . N 6 HOH 110 810 204 HOH HOH B . N 6 HOH 111 811 224 HOH HOH B . N 6 HOH 112 812 299 HOH HOH B . N 6 HOH 113 813 256 HOH HOH B . N 6 HOH 114 814 107 HOH HOH B . N 6 HOH 115 815 61 HOH HOH B . N 6 HOH 116 816 155 HOH HOH B . N 6 HOH 117 817 156 HOH HOH B . N 6 HOH 118 818 360 HOH HOH B . N 6 HOH 119 819 308 HOH HOH B . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 O ? A ILE 74 ? A ILE 72 ? 1_555 NA ? E NA . ? A NA 603 ? 1_555 O ? A ASP 77 ? A ASP 75 ? 1_555 96.6 ? 2 O ? A ILE 74 ? A ILE 72 ? 1_555 NA ? E NA . ? A NA 603 ? 1_555 O ? A LEU 80 ? A LEU 78 ? 1_555 78.1 ? 3 O ? A ASP 77 ? A ASP 75 ? 1_555 NA ? E NA . ? A NA 603 ? 1_555 O ? A LEU 80 ? A LEU 78 ? 1_555 68.7 ? 4 O ? A ILE 74 ? A ILE 72 ? 1_555 NA ? E NA . ? A NA 603 ? 1_555 O ? A LEU 81 ? A LEU 79 ? 1_555 119.1 ? 5 O ? A ASP 77 ? A ASP 75 ? 1_555 NA ? E NA . ? A NA 603 ? 1_555 O ? A LEU 81 ? A LEU 79 ? 1_555 108.6 ? 6 O ? A LEU 80 ? A LEU 78 ? 1_555 NA ? E NA . ? A NA 603 ? 1_555 O ? A LEU 81 ? A LEU 79 ? 1_555 62.6 ? 7 O ? A ILE 74 ? A ILE 72 ? 1_555 NA ? E NA . ? A NA 603 ? 1_555 O ? M HOH . ? A HOH 754 ? 1_555 68.2 ? 8 O ? A ASP 77 ? A ASP 75 ? 1_555 NA ? E NA . ? A NA 603 ? 1_555 O ? M HOH . ? A HOH 754 ? 1_555 148.8 ? 9 O ? A LEU 80 ? A LEU 78 ? 1_555 NA ? E NA . ? A NA 603 ? 1_555 O ? M HOH . ? A HOH 754 ? 1_555 81.2 ? 10 O ? A LEU 81 ? A LEU 79 ? 1_555 NA ? E NA . ? A NA 603 ? 1_555 O ? M HOH . ? A HOH 754 ? 1_555 61.7 ? 11 O ? B ILE 74 ? B ILE 72 ? 1_555 NA ? J NA . ? B NA 603 ? 1_555 O ? B LEU 80 ? B LEU 78 ? 1_555 94.5 ? 12 O ? B ILE 74 ? B ILE 72 ? 1_555 NA ? J NA . ? B NA 603 ? 1_555 O ? B LEU 81 ? B LEU 79 ? 1_555 165.6 ? 13 O ? B LEU 80 ? B LEU 78 ? 1_555 NA ? J NA . ? B NA 603 ? 1_555 O ? B LEU 81 ? B LEU 79 ? 1_555 81.9 ? 14 O ? B ILE 74 ? B ILE 72 ? 1_555 NA ? J NA . ? B NA 603 ? 1_555 O ? N HOH . ? B HOH 714 ? 1_555 88.4 ? 15 O ? B LEU 80 ? B LEU 78 ? 1_555 NA ? J NA . ? B NA 603 ? 1_555 O ? N HOH . ? B HOH 714 ? 1_555 112.5 ? 16 O ? B LEU 81 ? B LEU 79 ? 1_555 NA ? J NA . ? B NA 603 ? 1_555 O ? N HOH . ? B HOH 714 ? 1_555 105.9 ? 17 O ? B ILE 74 ? B ILE 72 ? 1_555 NA ? J NA . ? B NA 603 ? 1_555 O ? N HOH . ? B HOH 708 ? 1_555 101.6 ? 18 O ? B LEU 80 ? B LEU 78 ? 1_555 NA ? J NA . ? B NA 603 ? 1_555 O ? N HOH . ? B HOH 708 ? 1_555 123.3 ? 19 O ? B LEU 81 ? B LEU 79 ? 1_555 NA ? J NA . ? B NA 603 ? 1_555 O ? N HOH . ? B HOH 708 ? 1_555 69.6 ? 20 O ? N HOH . ? B HOH 714 ? 1_555 NA ? J NA . ? B NA 603 ? 1_555 O ? N HOH . ? B HOH 708 ? 1_555 121.9 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2015-09-09 2 'Structure model' 1 1 2015-10-07 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Database references' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? MOSFLM ? ? ? . 1 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? SCALA ? ? ? . 2 ? refinement ? ? ? ? ? ? ? ? ? ? ? BUSTER-TNT ? ? ? 'BUSTER 2.11.5' 3 ? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? 3.15 4 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ALA A 108 ? ? -78.13 46.15 2 1 SER A 143 ? ? -95.52 -63.80 3 1 ALA A 166 ? ? -147.40 -7.96 4 1 PHE A 189 ? ? -26.16 -54.36 5 1 ASP A 361 ? ? 56.43 8.53 6 1 CYS A 400 ? ? -114.51 70.80 7 1 LYS A 427 ? ? -165.11 105.28 8 1 ASP A 444 ? ? -78.77 -169.86 9 1 ALA A 475 ? ? -151.19 86.95 10 1 HIS B 87 ? ? -150.08 83.83 11 1 SER B 143 ? ? -91.63 -67.69 12 1 ALA B 166 ? ? -149.14 -16.53 13 1 TYR B 178 ? ? -115.68 64.00 14 1 ALA B 230 ? ? -58.96 -3.95 15 1 PRO B 336 ? ? -49.18 -9.54 16 1 ASN B 339 ? ? -110.80 53.49 17 1 PHE B 422 ? ? -125.41 -51.28 18 1 ASP B 436 ? ? -74.84 34.33 19 1 THR B 437 ? ? -83.03 -102.12 20 1 ALA B 461 ? ? -135.48 -92.74 21 1 LYS B 470 ? ? -64.97 95.76 22 1 PRO B 486 ? ? -90.09 31.28 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A LYS 23 ? CG ? A LYS 25 CG 2 1 Y 1 A LYS 23 ? CD ? A LYS 25 CD 3 1 Y 1 A LYS 23 ? CE ? A LYS 25 CE 4 1 Y 1 A LYS 23 ? NZ ? A LYS 25 NZ 5 1 Y 1 A GLU 48 ? CG ? A GLU 50 CG 6 1 Y 1 A GLU 48 ? CD ? A GLU 50 CD 7 1 Y 1 A GLU 48 ? OE1 ? A GLU 50 OE1 8 1 Y 1 A GLU 48 ? OE2 ? A GLU 50 OE2 9 1 Y 1 A ARG 243 ? CG ? A ARG 245 CG 10 1 Y 1 A ARG 243 ? CD ? A ARG 245 CD 11 1 Y 1 A ARG 243 ? NE ? A ARG 245 NE 12 1 Y 1 A ARG 243 ? CZ ? A ARG 245 CZ 13 1 Y 1 A ARG 243 ? NH1 ? A ARG 245 NH1 14 1 Y 1 A ARG 243 ? NH2 ? A ARG 245 NH2 15 1 Y 1 A GLN 259 ? CD ? A GLN 261 CD 16 1 Y 1 A GLN 259 ? OE1 ? A GLN 261 OE1 17 1 Y 1 A GLN 259 ? NE2 ? A GLN 261 NE2 18 1 Y 1 A VAL 370 ? CG1 ? A VAL 372 CG1 19 1 Y 1 A VAL 370 ? CG2 ? A VAL 372 CG2 20 1 Y 1 A GLU 373 ? CG ? A GLU 375 CG 21 1 Y 1 A GLU 373 ? CD ? A GLU 375 CD 22 1 Y 1 A GLU 373 ? OE1 ? A GLU 375 OE1 23 1 Y 1 A GLU 373 ? OE2 ? A GLU 375 OE2 24 1 Y 1 A ARG 405 ? CG ? A ARG 407 CG 25 1 Y 1 A ARG 405 ? CD ? A ARG 407 CD 26 1 Y 1 A ARG 405 ? NE ? A ARG 407 NE 27 1 Y 1 A ARG 405 ? CZ ? A ARG 407 CZ 28 1 Y 1 A ARG 405 ? NH1 ? A ARG 407 NH1 29 1 Y 1 A ARG 405 ? NH2 ? A ARG 407 NH2 30 1 Y 1 A LYS 420 ? CG ? A LYS 422 CG 31 1 Y 1 A LYS 420 ? CD ? A LYS 422 CD 32 1 Y 1 A LYS 420 ? CE ? A LYS 422 CE 33 1 Y 1 A LYS 420 ? NZ ? A LYS 422 NZ 34 1 Y 1 A ARG 442 ? CZ ? A ARG 444 CZ 35 1 Y 1 A ARG 442 ? NH1 ? A ARG 444 NH1 36 1 Y 1 A ARG 442 ? NH2 ? A ARG 444 NH2 37 1 Y 1 A ARG 452 ? CG ? A ARG 454 CG 38 1 Y 1 A ARG 452 ? CD ? A ARG 454 CD 39 1 Y 1 A ARG 452 ? NE ? A ARG 454 NE 40 1 Y 1 A ARG 452 ? CZ ? A ARG 454 CZ 41 1 Y 1 A ARG 452 ? NH1 ? A ARG 454 NH1 42 1 Y 1 A ARG 452 ? NH2 ? A ARG 454 NH2 43 1 Y 1 A ARG 460 ? CG ? A ARG 462 CG 44 1 Y 1 A ARG 460 ? CD ? A ARG 462 CD 45 1 Y 1 A ARG 460 ? NE ? A ARG 462 NE 46 1 Y 1 A ARG 460 ? CZ ? A ARG 462 CZ 47 1 Y 1 A ARG 460 ? NH1 ? A ARG 462 NH1 48 1 Y 1 A ARG 460 ? NH2 ? A ARG 462 NH2 49 1 Y 1 A ARG 465 ? CG ? A ARG 467 CG 50 1 Y 1 A ARG 465 ? CD ? A ARG 467 CD 51 1 Y 1 A ARG 465 ? NE ? A ARG 467 NE 52 1 Y 1 A ARG 465 ? CZ ? A ARG 467 CZ 53 1 Y 1 A ARG 465 ? NH1 ? A ARG 467 NH1 54 1 Y 1 A ARG 465 ? NH2 ? A ARG 467 NH2 55 1 Y 1 A ARG 467 ? CZ ? A ARG 469 CZ 56 1 Y 1 A ARG 467 ? NH1 ? A ARG 469 NH1 57 1 Y 1 A ARG 467 ? NH2 ? A ARG 469 NH2 58 1 Y 1 A THR 482 ? OG1 ? A THR 484 OG1 59 1 Y 1 A THR 482 ? CG2 ? A THR 484 CG2 60 1 Y 1 B LYS 23 ? CG ? B LYS 25 CG 61 1 Y 1 B LYS 23 ? CD ? B LYS 25 CD 62 1 Y 1 B LYS 23 ? CE ? B LYS 25 CE 63 1 Y 1 B LYS 23 ? NZ ? B LYS 25 NZ 64 1 Y 1 B GLU 48 ? CG ? B GLU 50 CG 65 1 Y 1 B GLU 48 ? CD ? B GLU 50 CD 66 1 Y 1 B GLU 48 ? OE1 ? B GLU 50 OE1 67 1 Y 1 B GLU 48 ? OE2 ? B GLU 50 OE2 68 1 Y 1 B LYS 240 ? CG ? B LYS 242 CG 69 1 Y 1 B LYS 240 ? CD ? B LYS 242 CD 70 1 Y 1 B LYS 240 ? CE ? B LYS 242 CE 71 1 Y 1 B LYS 240 ? NZ ? B LYS 242 NZ 72 1 Y 1 B ARG 243 ? CG ? B ARG 245 CG 73 1 Y 1 B ARG 243 ? CD ? B ARG 245 CD 74 1 Y 1 B ARG 243 ? NE ? B ARG 245 NE 75 1 Y 1 B ARG 243 ? CZ ? B ARG 245 CZ 76 1 Y 1 B ARG 243 ? NH1 ? B ARG 245 NH1 77 1 Y 1 B ARG 243 ? NH2 ? B ARG 245 NH2 78 1 Y 1 B VAL 370 ? CG1 ? B VAL 372 CG1 79 1 Y 1 B VAL 370 ? CG2 ? B VAL 372 CG2 80 1 Y 1 B GLU 373 ? CG ? B GLU 375 CG 81 1 Y 1 B GLU 373 ? CD ? B GLU 375 CD 82 1 Y 1 B GLU 373 ? OE1 ? B GLU 375 OE1 83 1 Y 1 B GLU 373 ? OE2 ? B GLU 375 OE2 84 1 Y 1 B LYS 420 ? CD ? B LYS 422 CD 85 1 Y 1 B LYS 420 ? CE ? B LYS 422 CE 86 1 Y 1 B LYS 420 ? NZ ? B LYS 422 NZ 87 1 Y 1 B ASP 436 ? CG ? B ASP 438 CG 88 1 Y 1 B ASP 436 ? OD1 ? B ASP 438 OD1 89 1 Y 1 B ASP 436 ? OD2 ? B ASP 438 OD2 90 1 Y 1 B ARG 442 ? CZ ? B ARG 444 CZ 91 1 Y 1 B ARG 442 ? NH1 ? B ARG 444 NH1 92 1 Y 1 B ARG 442 ? NH2 ? B ARG 444 NH2 93 1 Y 1 B ARG 445 ? CG ? B ARG 447 CG 94 1 Y 1 B ARG 445 ? CD ? B ARG 447 CD 95 1 Y 1 B ARG 445 ? NE ? B ARG 447 NE 96 1 Y 1 B ARG 445 ? CZ ? B ARG 447 CZ 97 1 Y 1 B ARG 445 ? NH1 ? B ARG 447 NH1 98 1 Y 1 B ARG 445 ? NH2 ? B ARG 447 NH2 99 1 Y 1 B ARG 452 ? CG ? B ARG 454 CG 100 1 Y 1 B ARG 452 ? CD ? B ARG 454 CD 101 1 Y 1 B ARG 452 ? NE ? B ARG 454 NE 102 1 Y 1 B ARG 452 ? CZ ? B ARG 454 CZ 103 1 Y 1 B ARG 452 ? NH1 ? B ARG 454 NH1 104 1 Y 1 B ARG 452 ? NH2 ? B ARG 454 NH2 105 1 Y 1 B ARG 460 ? CG ? B ARG 462 CG 106 1 Y 1 B ARG 460 ? CD ? B ARG 462 CD 107 1 Y 1 B ARG 460 ? NE ? B ARG 462 NE 108 1 Y 1 B ARG 460 ? CZ ? B ARG 462 CZ 109 1 Y 1 B ARG 460 ? NH1 ? B ARG 462 NH1 110 1 Y 1 B ARG 460 ? NH2 ? B ARG 462 NH2 111 1 Y 1 B ARG 465 ? CG ? B ARG 467 CG 112 1 Y 1 B ARG 465 ? CD ? B ARG 467 CD 113 1 Y 1 B ARG 465 ? NE ? B ARG 467 NE 114 1 Y 1 B ARG 465 ? CZ ? B ARG 467 CZ 115 1 Y 1 B ARG 465 ? NH1 ? B ARG 467 NH1 116 1 Y 1 B ARG 465 ? NH2 ? B ARG 467 NH2 117 1 Y 1 B ARG 467 ? CZ ? B ARG 469 CZ 118 1 Y 1 B ARG 467 ? NH1 ? B ARG 469 NH1 119 1 Y 1 B ARG 467 ? NH2 ? B ARG 469 NH2 120 1 Y 1 B THR 482 ? OG1 ? B THR 484 OG1 121 1 Y 1 B THR 482 ? CG2 ? B THR 484 CG2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A MET -1 ? A MET 1 2 1 Y 1 A ALA 0 ? A ALA 2 3 1 Y 1 A LEU 1 ? A LEU 3 4 1 Y 1 A GLY 2 ? A GLY 4 5 1 Y 1 A SER 3 ? A SER 5 6 1 Y 1 A LEU 4 ? A LEU 6 7 1 Y 1 A LEU 5 ? A LEU 7 8 1 Y 1 A ALA 6 ? A ALA 8 9 1 Y 1 A LEU 7 ? A LEU 9 10 1 Y 1 A LEU 8 ? A LEU 10 11 1 Y 1 A ALA 9 ? A ALA 11 12 1 Y 1 A LEU 10 ? A LEU 12 13 1 Y 1 A LEU 11 ? A LEU 13 14 1 Y 1 A LEU 12 ? A LEU 14 15 1 Y 1 A LEU 13 ? A LEU 15 16 1 Y 1 A TRP 14 ? A TRP 16 17 1 Y 1 A GLY 15 ? A GLY 17 18 1 Y 1 A ALA 16 ? A ALA 18 19 1 Y 1 A VAL 17 ? A VAL 19 20 1 Y 1 A ALA 18 ? A ALA 20 21 1 Y 1 A GLU 19 ? A GLU 21 22 1 Y 1 A GLY 20 ? A GLY 22 23 1 Y 1 A PRO 21 ? A PRO 23 24 1 Y 1 A ALA 22 ? A ALA 24 25 1 Y 1 A LEU 110 ? A LEU 112 26 1 Y 1 A SER 111 ? A SER 113 27 1 Y 1 A ARG 112 ? A ARG 114 28 1 Y 1 A GLY 113 ? A GLY 115 29 1 Y 1 A ALA 114 ? A ALA 116 30 1 Y 1 A ASP 115 ? A ASP 117 31 1 Y 1 A GLY 116 ? A GLY 118 32 1 Y 1 A SER 117 ? A SER 119 33 1 Y 1 A ARG 118 ? A ARG 120 34 1 Y 1 A HIS 119 ? A HIS 121 35 1 Y 1 A ILE 120 ? A ILE 122 36 1 Y 1 A CYS 121 ? A CYS 123 37 1 Y 1 A PRO 122 ? A PRO 124 38 1 Y 1 A ASP 123 ? A ASP 125 39 1 Y 1 A GLY 124 ? A GLY 126 40 1 Y 1 A SER 125 ? A SER 127 41 1 Y 1 A TYR 126 ? A TYR 128 42 1 Y 1 A ALA 127 ? A ALA 129 43 1 Y 1 A THR 128 ? A THR 130 44 1 Y 1 A HIS 129 ? A HIS 131 45 1 Y 1 A GLY 130 ? A GLY 132 46 1 Y 1 A ASP 131 ? A ASP 133 47 1 Y 1 A ALA 132 ? A ALA 134 48 1 Y 1 A PRO 133 ? A PRO 135 49 1 Y 1 A GLN 359 ? A GLN 361 50 1 Y 1 A GLY 462 ? A GLY 464 51 1 Y 1 A SER 463 ? A SER 465 52 1 Y 1 A ALA 488 ? A ALA 490 53 1 Y 1 A SER 489 ? A SER 491 54 1 Y 1 A PRO 490 ? A PRO 492 55 1 Y 1 A SER 491 ? A SER 493 56 1 Y 1 A ALA 492 ? A ALA 494 57 1 Y 1 A GLY 493 ? A GLY 495 58 1 Y 1 A GLU 494 ? A GLU 496 59 1 Y 1 A GLY 495 ? A GLY 497 60 1 Y 1 A HIS 496 ? A HIS 498 61 1 Y 1 A HIS 497 ? A HIS 499 62 1 Y 1 A HIS 498 ? A HIS 500 63 1 Y 1 A HIS 499 ? A HIS 501 64 1 Y 1 A HIS 500 ? A HIS 502 65 1 Y 1 A HIS 501 ? A HIS 503 66 1 Y 1 B MET -1 ? B MET 1 67 1 Y 1 B ALA 0 ? B ALA 2 68 1 Y 1 B LEU 1 ? B LEU 3 69 1 Y 1 B GLY 2 ? B GLY 4 70 1 Y 1 B SER 3 ? B SER 5 71 1 Y 1 B LEU 4 ? B LEU 6 72 1 Y 1 B LEU 5 ? B LEU 7 73 1 Y 1 B ALA 6 ? B ALA 8 74 1 Y 1 B LEU 7 ? B LEU 9 75 1 Y 1 B LEU 8 ? B LEU 10 76 1 Y 1 B ALA 9 ? B ALA 11 77 1 Y 1 B LEU 10 ? B LEU 12 78 1 Y 1 B LEU 11 ? B LEU 13 79 1 Y 1 B LEU 12 ? B LEU 14 80 1 Y 1 B LEU 13 ? B LEU 15 81 1 Y 1 B TRP 14 ? B TRP 16 82 1 Y 1 B GLY 15 ? B GLY 17 83 1 Y 1 B ALA 16 ? B ALA 18 84 1 Y 1 B VAL 17 ? B VAL 19 85 1 Y 1 B ALA 18 ? B ALA 20 86 1 Y 1 B GLU 19 ? B GLU 21 87 1 Y 1 B GLY 20 ? B GLY 22 88 1 Y 1 B PRO 21 ? B PRO 23 89 1 Y 1 B ALA 22 ? B ALA 24 90 1 Y 1 B LEU 110 ? B LEU 112 91 1 Y 1 B SER 111 ? B SER 113 92 1 Y 1 B ARG 112 ? B ARG 114 93 1 Y 1 B GLY 113 ? B GLY 115 94 1 Y 1 B ALA 114 ? B ALA 116 95 1 Y 1 B ASP 115 ? B ASP 117 96 1 Y 1 B GLY 116 ? B GLY 118 97 1 Y 1 B SER 117 ? B SER 119 98 1 Y 1 B ARG 118 ? B ARG 120 99 1 Y 1 B HIS 119 ? B HIS 121 100 1 Y 1 B ILE 120 ? B ILE 122 101 1 Y 1 B CYS 121 ? B CYS 123 102 1 Y 1 B PRO 122 ? B PRO 124 103 1 Y 1 B ASP 123 ? B ASP 125 104 1 Y 1 B GLY 124 ? B GLY 126 105 1 Y 1 B SER 125 ? B SER 127 106 1 Y 1 B TYR 126 ? B TYR 128 107 1 Y 1 B ALA 127 ? B ALA 129 108 1 Y 1 B THR 128 ? B THR 130 109 1 Y 1 B HIS 129 ? B HIS 131 110 1 Y 1 B GLY 130 ? B GLY 132 111 1 Y 1 B ASP 131 ? B ASP 133 112 1 Y 1 B ALA 132 ? B ALA 134 113 1 Y 1 B PRO 133 ? B PRO 135 114 1 Y 1 B ARG 433 ? B ARG 435 115 1 Y 1 B PRO 434 ? B PRO 436 116 1 Y 1 B SER 463 ? B SER 465 117 1 Y 1 B ALA 488 ? B ALA 490 118 1 Y 1 B SER 489 ? B SER 491 119 1 Y 1 B PRO 490 ? B PRO 492 120 1 Y 1 B SER 491 ? B SER 493 121 1 Y 1 B ALA 492 ? B ALA 494 122 1 Y 1 B GLY 493 ? B GLY 495 123 1 Y 1 B GLU 494 ? B GLU 496 124 1 Y 1 B GLY 495 ? B GLY 497 125 1 Y 1 B HIS 496 ? B HIS 498 126 1 Y 1 B HIS 497 ? B HIS 499 127 1 Y 1 B HIS 498 ? B HIS 500 128 1 Y 1 B HIS 499 ? B HIS 501 129 1 Y 1 B HIS 500 ? B HIS 502 130 1 Y 1 B HIS 501 ? B HIS 503 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 'GAMMA-L-GLUTAMIC ACID' GGL 3 'CHLORIDE ION' CL 4 'SODIUM ION' NA 5 N-ACETYL-D-GLUCOSAMINE NAG 6 water HOH #