data_4Z80 # _entry.id 4Z80 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.286 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4Z80 WWPDB D_1000208784 # _pdbx_database_related.content_type unspecified _pdbx_database_related.db_id 4z81 _pdbx_database_related.db_name PDB _pdbx_database_related.details . # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 4Z80 _pdbx_database_status.recvd_initial_deposition_date 2015-04-08 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Parker, M.L.' 1 'Boulanger, M.J.' 2 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev Proc.Natl.Acad.Sci.USA _citation.journal_id_ASTM PNASA6 _citation.journal_id_CSD 0040 _citation.journal_id_ISSN 1091-6490 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 113 _citation.language ? _citation.page_first 398 _citation.page_last 403 _citation.title 'Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair.' _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1073/pnas.1515898113 _citation.pdbx_database_id_PubMed 26712012 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Parker, M.L.' 1 primary 'Penarete-Vargas, D.M.' 2 primary 'Hamilton, P.T.' 3 primary 'Guerin, A.' 4 primary 'Dubey, J.P.' 5 primary 'Perlman, S.J.' 6 primary 'Spano, F.' 7 primary 'Lebrun, M.' 8 primary 'Boulanger, M.J.' 9 # _cell.angle_alpha 90.00 _cell.angle_alpha_esd ? _cell.angle_beta 90.00 _cell.angle_beta_esd ? _cell.angle_gamma 120.00 _cell.angle_gamma_esd ? _cell.entry_id 4Z80 _cell.details ? _cell.formula_units_Z ? _cell.length_a 120.560 _cell.length_a_esd ? _cell.length_b 120.560 _cell.length_b_esd ? _cell.length_c 141.690 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 12 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 4Z80 _symmetry.cell_setting ? _symmetry.Int_Tables_number 170 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'P 65' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'EGF family domain-containing protein' 55659.262 2 ? ? 'residues 58-553' ? 2 polymer man 'Cytoadherence-linked asexual protein' 3633.070 2 ? ? 'residues 1292-1324' ? 3 non-polymer syn GLYCEROL 92.094 4 ? ? ? ? 4 non-polymer syn 'SULFATE ION' 96.063 3 ? ? ? ? 5 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 6 water nat water 18.015 1361 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;GSAMGSSTSTSRATYMDRFNIPKNHVDLIWDKDGTKSHTRGNTTYRWTERKSNVGVYVGYSEMYDSSAQAYCQSSSAKID TKTTVGAPYMAAGACPNYGKVIAFTKRDGSRSDMTRWKNEIHANVMPHSTTSCASRADPGAAEVAKSIEGFAMYAGYLTH CPYNVNVYRQDMVTDKEFDSTVCNFVTESNPLRFLDTTQRQSTQPYTEYAFHGKGGHKGYDYKGQTSHVGCPPYNPPHVT KGMKDSSWITGPFECSILSRCTTHCWPYKSGGNCFRSLPAMFDMSTGECRLLGYHTQDFRSSTCAELTTDDTNAFYCVRP MKTAASSNMVYVTSHTRPDHETKCPPREPLKNVRWGVVSKGKYCKPMNARASLSNATAEQCGQRLFMLSSADGSSLSSQV RGYHWATFVATDCNMGESCAATARGKCFFYSTVPECLIHSPTTMAFTSLSAVDPSIAIDPDSIAVLPEDKCVSVDCGAHG TCDVATGKCVCEPGFTGERCDAAALVPR ; ;GSAMGSSTSTSRATYMDRFNIPKNHVDLIWDKDGTKSHTRGNTTYRWTERKSNVGVYVGYSEMYDSSAQAYCQSSSAKID TKTTVGAPYMAAGACPNYGKVIAFTKRDGSRSDMTRWKNEIHANVMPHSTTSCASRADPGAAEVAKSIEGFAMYAGYLTH CPYNVNVYRQDMVTDKEFDSTVCNFVTESNPLRFLDTTQRQSTQPYTEYAFHGKGGHKGYDYKGQTSHVGCPPYNPPHVT KGMKDSSWITGPFECSILSRCTTHCWPYKSGGNCFRSLPAMFDMSTGECRLLGYHTQDFRSSTCAELTTDDTNAFYCVRP MKTAASSNMVYVTSHTRPDHETKCPPREPLKNVRWGVVSKGKYCKPMNARASLSNATAEQCGQRLFMLSSADGSSLSSQV RGYHWATFVATDCNMGESCAATARGKCFFYSTVPECLIHSPTTMAFTSLSAVDPSIAIDPDSIAVLPEDKCVSVDCGAHG TCDVATGKCVCEPGFTGERCDAAALVPR ; A,B ? 2 'polypeptide(L)' no no GSASQIVQNQSSLAPELSGCPPMGICMDGTIGDPIAS GSASQIVQNQSSLAPELSGCPPMGICMDGTIGDPIAS C,D ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLY n 1 2 SER n 1 3 ALA n 1 4 MET n 1 5 GLY n 1 6 SER n 1 7 SER n 1 8 THR n 1 9 SER n 1 10 THR n 1 11 SER n 1 12 ARG n 1 13 ALA n 1 14 THR n 1 15 TYR n 1 16 MET n 1 17 ASP n 1 18 ARG n 1 19 PHE n 1 20 ASN n 1 21 ILE n 1 22 PRO n 1 23 LYS n 1 24 ASN n 1 25 HIS n 1 26 VAL n 1 27 ASP n 1 28 LEU n 1 29 ILE n 1 30 TRP n 1 31 ASP n 1 32 LYS n 1 33 ASP n 1 34 GLY n 1 35 THR n 1 36 LYS n 1 37 SER n 1 38 HIS n 1 39 THR n 1 40 ARG n 1 41 GLY n 1 42 ASN n 1 43 THR n 1 44 THR n 1 45 TYR n 1 46 ARG n 1 47 TRP n 1 48 THR n 1 49 GLU n 1 50 ARG n 1 51 LYS n 1 52 SER n 1 53 ASN n 1 54 VAL n 1 55 GLY n 1 56 VAL n 1 57 TYR n 1 58 VAL n 1 59 GLY n 1 60 TYR n 1 61 SER n 1 62 GLU n 1 63 MET n 1 64 TYR n 1 65 ASP n 1 66 SER n 1 67 SER n 1 68 ALA n 1 69 GLN n 1 70 ALA n 1 71 TYR n 1 72 CYS n 1 73 GLN n 1 74 SER n 1 75 SER n 1 76 SER n 1 77 ALA n 1 78 LYS n 1 79 ILE n 1 80 ASP n 1 81 THR n 1 82 LYS n 1 83 THR n 1 84 THR n 1 85 VAL n 1 86 GLY n 1 87 ALA n 1 88 PRO n 1 89 TYR n 1 90 MET n 1 91 ALA n 1 92 ALA n 1 93 GLY n 1 94 ALA n 1 95 CYS n 1 96 PRO n 1 97 ASN n 1 98 TYR n 1 99 GLY n 1 100 LYS n 1 101 VAL n 1 102 ILE n 1 103 ALA n 1 104 PHE n 1 105 THR n 1 106 LYS n 1 107 ARG n 1 108 ASP n 1 109 GLY n 1 110 SER n 1 111 ARG n 1 112 SER n 1 113 ASP n 1 114 MET n 1 115 THR n 1 116 ARG n 1 117 TRP n 1 118 LYS n 1 119 ASN n 1 120 GLU n 1 121 ILE n 1 122 HIS n 1 123 ALA n 1 124 ASN n 1 125 VAL n 1 126 MET n 1 127 PRO n 1 128 HIS n 1 129 SER n 1 130 THR n 1 131 THR n 1 132 SER n 1 133 CYS n 1 134 ALA n 1 135 SER n 1 136 ARG n 1 137 ALA n 1 138 ASP n 1 139 PRO n 1 140 GLY n 1 141 ALA n 1 142 ALA n 1 143 GLU n 1 144 VAL n 1 145 ALA n 1 146 LYS n 1 147 SER n 1 148 ILE n 1 149 GLU n 1 150 GLY n 1 151 PHE n 1 152 ALA n 1 153 MET n 1 154 TYR n 1 155 ALA n 1 156 GLY n 1 157 TYR n 1 158 LEU n 1 159 THR n 1 160 HIS n 1 161 CYS n 1 162 PRO n 1 163 TYR n 1 164 ASN n 1 165 VAL n 1 166 ASN n 1 167 VAL n 1 168 TYR n 1 169 ARG n 1 170 GLN n 1 171 ASP n 1 172 MET n 1 173 VAL n 1 174 THR n 1 175 ASP n 1 176 LYS n 1 177 GLU n 1 178 PHE n 1 179 ASP n 1 180 SER n 1 181 THR n 1 182 VAL n 1 183 CYS n 1 184 ASN n 1 185 PHE n 1 186 VAL n 1 187 THR n 1 188 GLU n 1 189 SER n 1 190 ASN n 1 191 PRO n 1 192 LEU n 1 193 ARG n 1 194 PHE n 1 195 LEU n 1 196 ASP n 1 197 THR n 1 198 THR n 1 199 GLN n 1 200 ARG n 1 201 GLN n 1 202 SER n 1 203 THR n 1 204 GLN n 1 205 PRO n 1 206 TYR n 1 207 THR n 1 208 GLU n 1 209 TYR n 1 210 ALA n 1 211 PHE n 1 212 HIS n 1 213 GLY n 1 214 LYS n 1 215 GLY n 1 216 GLY n 1 217 HIS n 1 218 LYS n 1 219 GLY n 1 220 TYR n 1 221 ASP n 1 222 TYR n 1 223 LYS n 1 224 GLY n 1 225 GLN n 1 226 THR n 1 227 SER n 1 228 HIS n 1 229 VAL n 1 230 GLY n 1 231 CYS n 1 232 PRO n 1 233 PRO n 1 234 TYR n 1 235 ASN n 1 236 PRO n 1 237 PRO n 1 238 HIS n 1 239 VAL n 1 240 THR n 1 241 LYS n 1 242 GLY n 1 243 MET n 1 244 LYS n 1 245 ASP n 1 246 SER n 1 247 SER n 1 248 TRP n 1 249 ILE n 1 250 THR n 1 251 GLY n 1 252 PRO n 1 253 PHE n 1 254 GLU n 1 255 CYS n 1 256 SER n 1 257 ILE n 1 258 LEU n 1 259 SER n 1 260 ARG n 1 261 CYS n 1 262 THR n 1 263 THR n 1 264 HIS n 1 265 CYS n 1 266 TRP n 1 267 PRO n 1 268 TYR n 1 269 LYS n 1 270 SER n 1 271 GLY n 1 272 GLY n 1 273 ASN n 1 274 CYS n 1 275 PHE n 1 276 ARG n 1 277 SER n 1 278 LEU n 1 279 PRO n 1 280 ALA n 1 281 MET n 1 282 PHE n 1 283 ASP n 1 284 MET n 1 285 SER n 1 286 THR n 1 287 GLY n 1 288 GLU n 1 289 CYS n 1 290 ARG n 1 291 LEU n 1 292 LEU n 1 293 GLY n 1 294 TYR n 1 295 HIS n 1 296 THR n 1 297 GLN n 1 298 ASP n 1 299 PHE n 1 300 ARG n 1 301 SER n 1 302 SER n 1 303 THR n 1 304 CYS n 1 305 ALA n 1 306 GLU n 1 307 LEU n 1 308 THR n 1 309 THR n 1 310 ASP n 1 311 ASP n 1 312 THR n 1 313 ASN n 1 314 ALA n 1 315 PHE n 1 316 TYR n 1 317 CYS n 1 318 VAL n 1 319 ARG n 1 320 PRO n 1 321 MET n 1 322 LYS n 1 323 THR n 1 324 ALA n 1 325 ALA n 1 326 SER n 1 327 SER n 1 328 ASN n 1 329 MET n 1 330 VAL n 1 331 TYR n 1 332 VAL n 1 333 THR n 1 334 SER n 1 335 HIS n 1 336 THR n 1 337 ARG n 1 338 PRO n 1 339 ASP n 1 340 HIS n 1 341 GLU n 1 342 THR n 1 343 LYS n 1 344 CYS n 1 345 PRO n 1 346 PRO n 1 347 ARG n 1 348 GLU n 1 349 PRO n 1 350 LEU n 1 351 LYS n 1 352 ASN n 1 353 VAL n 1 354 ARG n 1 355 TRP n 1 356 GLY n 1 357 VAL n 1 358 VAL n 1 359 SER n 1 360 LYS n 1 361 GLY n 1 362 LYS n 1 363 TYR n 1 364 CYS n 1 365 LYS n 1 366 PRO n 1 367 MET n 1 368 ASN n 1 369 ALA n 1 370 ARG n 1 371 ALA n 1 372 SER n 1 373 LEU n 1 374 SER n 1 375 ASN n 1 376 ALA n 1 377 THR n 1 378 ALA n 1 379 GLU n 1 380 GLN n 1 381 CYS n 1 382 GLY n 1 383 GLN n 1 384 ARG n 1 385 LEU n 1 386 PHE n 1 387 MET n 1 388 LEU n 1 389 SER n 1 390 SER n 1 391 ALA n 1 392 ASP n 1 393 GLY n 1 394 SER n 1 395 SER n 1 396 LEU n 1 397 SER n 1 398 SER n 1 399 GLN n 1 400 VAL n 1 401 ARG n 1 402 GLY n 1 403 TYR n 1 404 HIS n 1 405 TRP n 1 406 ALA n 1 407 THR n 1 408 PHE n 1 409 VAL n 1 410 ALA n 1 411 THR n 1 412 ASP n 1 413 CYS n 1 414 ASN n 1 415 MET n 1 416 GLY n 1 417 GLU n 1 418 SER n 1 419 CYS n 1 420 ALA n 1 421 ALA n 1 422 THR n 1 423 ALA n 1 424 ARG n 1 425 GLY n 1 426 LYS n 1 427 CYS n 1 428 PHE n 1 429 PHE n 1 430 TYR n 1 431 SER n 1 432 THR n 1 433 VAL n 1 434 PRO n 1 435 GLU n 1 436 CYS n 1 437 LEU n 1 438 ILE n 1 439 HIS n 1 440 SER n 1 441 PRO n 1 442 THR n 1 443 THR n 1 444 MET n 1 445 ALA n 1 446 PHE n 1 447 THR n 1 448 SER n 1 449 LEU n 1 450 SER n 1 451 ALA n 1 452 VAL n 1 453 ASP n 1 454 PRO n 1 455 SER n 1 456 ILE n 1 457 ALA n 1 458 ILE n 1 459 ASP n 1 460 PRO n 1 461 ASP n 1 462 SER n 1 463 ILE n 1 464 ALA n 1 465 VAL n 1 466 LEU n 1 467 PRO n 1 468 GLU n 1 469 ASP n 1 470 LYS n 1 471 CYS n 1 472 VAL n 1 473 SER n 1 474 VAL n 1 475 ASP n 1 476 CYS n 1 477 GLY n 1 478 ALA n 1 479 HIS n 1 480 GLY n 1 481 THR n 1 482 CYS n 1 483 ASP n 1 484 VAL n 1 485 ALA n 1 486 THR n 1 487 GLY n 1 488 LYS n 1 489 CYS n 1 490 VAL n 1 491 CYS n 1 492 GLU n 1 493 PRO n 1 494 GLY n 1 495 PHE n 1 496 THR n 1 497 GLY n 1 498 GLU n 1 499 ARG n 1 500 CYS n 1 501 ASP n 1 502 ALA n 1 503 ALA n 1 504 ALA n 1 505 LEU n 1 506 VAL n 1 507 PRO n 1 508 ARG n 2 1 GLY n 2 2 SER n 2 3 ALA n 2 4 SER n 2 5 GLN n 2 6 ILE n 2 7 VAL n 2 8 GLN n 2 9 ASN n 2 10 GLN n 2 11 SER n 2 12 SER n 2 13 LEU n 2 14 ALA n 2 15 PRO n 2 16 GLU n 2 17 LEU n 2 18 SER n 2 19 GLY n 2 20 CYS n 2 21 PRO n 2 22 PRO n 2 23 MET n 2 24 GLY n 2 25 ILE n 2 26 CYS n 2 27 MET n 2 28 ASP n 2 29 GLY n 2 30 THR n 2 31 ILE n 2 32 GLY n 2 33 ASP n 2 34 PRO n 2 35 ILE n 2 36 ALA n 2 37 SER n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample 'Biological sequence' 1 508 ? ? TGVEG_294330 ? ? ? ? ? ? 'Toxoplasma gondii' 5811 ? ? ? ? ? ? ? 'Cabbage Looper' 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? Baculovirus pAcGP67b ? ? ? ? ? 2 1 sample 'Biological sequence' 1 37 ? ? TGVEG_294400 ? ? ? ? ? ? 'Toxoplasma gondii' 5811 ? ? ? ? ? ? ? ? 'Escherichia coli' 511693 ? ? ? ? ? ? ? ? BL21 ? ? ? ? ? plasmid ? ? ? pET32a ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 UNP V4YLU4_TOXGO V4YLU4 ? 1 ;SSTSTSRATYMDRFNIPKNHVDLIWDKDGTKSHTRGNTTYRWTERKSNVGVYVGYSEMYDSSAQAYCQSSSAKIDTKTTV GAPYMAAGACPNYGKVIAFTKRDGSRSDMTRWKNEIHANVMPHSTTSCASRADPGAAEVAKSIEGFAMYAGYLTHCPYNV NVYRQDMVTDKEFDSTVCNFVTESNPLRFLDTTQRQSTQPYTEYAFHGKGGHKGYDYKGQTSHVGCPPYNPPHVTKGMKD SSWITGPFECSILSRCTTHCWPYKSGGNCFRSLPAMFDMSTGECRLLGYHTQDFRSSTCAELTTDDTNAFYCVRPMKTAA SSNMVYVTSHTRPDHETKCPPREPLKNVRWGVVSKGKYCKPMNARASLSNATAEQCGQRLFMLSSADGSSLSSQVRGYHW ATFVATDCNMGESCAATARGKCFFYSTVPECLIHSPTTMAFTSLSAVDPSIAIDPDSIAVLPEDKCVSVDCGAHGTCDVA TGKCVCEPGFTGERCD ; 58 2 UNP B6KQU6_TOXGO B6KQU6 ? 2 QIVQNQSSLAPELSGCPPMGICMDGTIGDPIAS 1292 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4Z80 A 6 ? 501 ? V4YLU4 58 ? 553 ? 58 553 2 2 4Z80 C 5 ? 37 ? B6KQU6 1292 ? 1324 ? 1292 1324 3 1 4Z80 B 6 ? 501 ? V4YLU4 58 ? 553 ? 58 553 4 2 4Z80 D 5 ? 37 ? B6KQU6 1292 ? 1324 ? 1292 1324 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4Z80 GLY A 1 ? UNP V4YLU4 ? ? 'expression tag' 53 1 1 4Z80 SER A 2 ? UNP V4YLU4 ? ? 'expression tag' 54 2 1 4Z80 ALA A 3 ? UNP V4YLU4 ? ? 'expression tag' 55 3 1 4Z80 MET A 4 ? UNP V4YLU4 ? ? 'expression tag' 56 4 1 4Z80 GLY A 5 ? UNP V4YLU4 ? ? 'expression tag' 57 5 1 4Z80 ALA A 502 ? UNP V4YLU4 ? ? 'expression tag' 554 6 1 4Z80 ALA A 503 ? UNP V4YLU4 ? ? 'expression tag' 555 7 1 4Z80 ALA A 504 ? UNP V4YLU4 ? ? 'expression tag' 556 8 1 4Z80 LEU A 505 ? UNP V4YLU4 ? ? 'expression tag' 557 9 1 4Z80 VAL A 506 ? UNP V4YLU4 ? ? 'expression tag' 558 10 1 4Z80 PRO A 507 ? UNP V4YLU4 ? ? 'expression tag' 559 11 1 4Z80 ARG A 508 ? UNP V4YLU4 ? ? 'expression tag' 560 12 2 4Z80 GLY C 1 ? UNP B6KQU6 ? ? 'expression tag' 1288 13 2 4Z80 SER C 2 ? UNP B6KQU6 ? ? 'expression tag' 1289 14 2 4Z80 ALA C 3 ? UNP B6KQU6 ? ? 'expression tag' 1290 15 2 4Z80 SER C 4 ? UNP B6KQU6 ? ? 'expression tag' 1291 16 3 4Z80 GLY B 1 ? UNP V4YLU4 ? ? 'expression tag' 53 17 3 4Z80 SER B 2 ? UNP V4YLU4 ? ? 'expression tag' 54 18 3 4Z80 ALA B 3 ? UNP V4YLU4 ? ? 'expression tag' 55 19 3 4Z80 MET B 4 ? UNP V4YLU4 ? ? 'expression tag' 56 20 3 4Z80 GLY B 5 ? UNP V4YLU4 ? ? 'expression tag' 57 21 3 4Z80 ALA B 502 ? UNP V4YLU4 ? ? 'expression tag' 554 22 3 4Z80 ALA B 503 ? UNP V4YLU4 ? ? 'expression tag' 555 23 3 4Z80 ALA B 504 ? UNP V4YLU4 ? ? 'expression tag' 556 24 3 4Z80 LEU B 505 ? UNP V4YLU4 ? ? 'expression tag' 557 25 3 4Z80 VAL B 506 ? UNP V4YLU4 ? ? 'expression tag' 558 26 3 4Z80 PRO B 507 ? UNP V4YLU4 ? ? 'expression tag' 559 27 3 4Z80 ARG B 508 ? UNP V4YLU4 ? ? 'expression tag' 560 28 4 4Z80 GLY D 1 ? UNP B6KQU6 ? ? 'expression tag' 1288 29 4 4Z80 SER D 2 ? UNP B6KQU6 ? ? 'expression tag' 1289 30 4 4Z80 ALA D 3 ? UNP B6KQU6 ? ? 'expression tag' 1290 31 4 4Z80 SER D 4 ? UNP B6KQU6 ? ? 'expression tag' 1291 32 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 4Z80 _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.71 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 54.66 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH 8.5 _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 291 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '0.2 M Lithium sulfate, 0.1 M Tris-HCl pH 8.5, 25% PEG3350' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'RAYONIX MX-300' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2013-12-13 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator 'ACCEL/BRUKER double crystal' _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.0332 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'CLSI BEAMLINE 08ID-1' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 1.0332 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline 08ID-1 _diffrn_source.pdbx_synchrotron_site CLSI # _reflns.B_iso_Wilson_estimate 13.5 _reflns.entry_id 4Z80 _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 1.53 _reflns.d_resolution_low 37.18 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all 175481 _reflns.number_obs 175481 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 99.9 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 7.6 _reflns.pdbx_Rmerge_I_obs 0.102 _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 10.5 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _reflns_shell.d_res_high 1.53 _reflns_shell.d_res_low 1.56 _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_obs 2.6 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_obs ? _reflns_shell.percent_possible_all 99.4 _reflns_shell.percent_possible_obs ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_obs 0.458 _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_gt ? _reflns_shell.number_unique_gt ? _reflns_shell.percent_possible_gt ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.pdbx_redundancy 6.4 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_CC_half ? _reflns_shell.pdbx_R_split ? # _refine.aniso_B[1][1] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][2] ? _refine.aniso_B[2][3] ? _refine.aniso_B[3][3] ? _refine.B_iso_max ? _refine.B_iso_mean ? _refine.B_iso_min ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.details ? _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 4Z80 _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 1.53 _refine.ls_d_res_low 37.178 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 175406 _refine.ls_number_reflns_R_free 8827 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 99.92 _refine.ls_percent_reflns_R_free 5.03 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.1537 _refine.ls_R_factor_R_free 0.1715 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.1527 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.37 _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' _refine.pdbx_method_to_determine_struct SAD _refine.pdbx_starting_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_R_Free_selection_details 'random selection' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error 16.97 _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B ? _refine.overall_SU_ML 0.13 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 7636 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 53 _refine_hist.number_atoms_solvent 1361 _refine_hist.number_atoms_total 9050 _refine_hist.d_res_high 1.53 _refine_hist.d_res_low 37.178 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.criterion _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.rejects _refine_ls_restr.type _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' ? 0.006 ? 7934 ? f_bond_d ? ? 'X-RAY DIFFRACTION' ? 1.083 ? 10748 ? f_angle_d ? ? 'X-RAY DIFFRACTION' ? 12.304 ? 2877 ? f_dihedral_angle_d ? ? 'X-RAY DIFFRACTION' ? 0.042 ? 1157 ? f_chiral_restr ? ? 'X-RAY DIFFRACTION' ? 0.005 ? 1394 ? f_plane_restr ? ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.R_factor_all _refine_ls_shell.R_factor_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.R_factor_R_work _refine_ls_shell.redundancy_reflns_all _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.wR_factor_all _refine_ls_shell.wR_factor_obs _refine_ls_shell.wR_factor_R_free _refine_ls_shell.wR_factor_R_work _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.pdbx_phase_error _refine_ls_shell.pdbx_fsc_work _refine_ls_shell.pdbx_fsc_free 'X-RAY DIFFRACTION' 1.53 1.5464 . . 304 5497 99.00 . . . 0.2534 . 0.2179 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.5464 1.5646 . . 323 5503 100.00 . . . 0.2428 . 0.2123 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.5646 1.5837 . . 288 5509 100.00 . . . 0.2275 . 0.1990 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.5837 1.6037 . . 304 5543 100.00 . . . 0.2166 . 0.1894 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.6037 1.6248 . . 299 5549 100.00 . . . 0.2269 . 0.1932 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.6248 1.6471 . . 282 5574 100.00 . . . 0.2286 . 0.1912 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.6471 1.6706 . . 306 5512 100.00 . . . 0.2137 . 0.1836 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.6706 1.6955 . . 274 5559 100.00 . . . 0.2027 . 0.1795 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.6955 1.7220 . . 284 5571 100.00 . . . 0.2221 . 0.1763 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.7220 1.7503 . . 282 5558 100.00 . . . 0.2037 . 0.1765 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.7503 1.7804 . . 300 5524 100.00 . . . 0.2039 . 0.1738 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.7804 1.8128 . . 285 5541 100.00 . . . 0.1969 . 0.1710 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.8128 1.8477 . . 290 5582 100.00 . . . 0.2024 . 0.1718 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.8477 1.8854 . . 290 5565 100.00 . . . 0.1966 . 0.1663 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.8854 1.9264 . . 274 5547 100.00 . . . 0.1796 . 0.1598 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.9264 1.9712 . . 260 5629 100.00 . . . 0.1844 . 0.1604 . . . . . . . . . . 'X-RAY DIFFRACTION' 1.9712 2.0205 . . 335 5473 100.00 . . . 0.1857 . 0.1576 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.0205 2.0751 . . 280 5566 100.00 . . . 0.1753 . 0.1582 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.0751 2.1362 . . 275 5578 100.00 . . . 0.1746 . 0.1582 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.1362 2.2051 . . 302 5525 100.00 . . . 0.1891 . 0.1532 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.2051 2.2839 . . 298 5576 100.00 . . . 0.1709 . 0.1499 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.2839 2.3753 . . 294 5551 100.00 . . . 0.1525 . 0.1421 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.3753 2.4834 . . 315 5547 100.00 . . . 0.1703 . 0.1447 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.4834 2.6143 . . 286 5589 100.00 . . . 0.1539 . 0.1408 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.6143 2.7781 . . 293 5566 100.00 . . . 0.1700 . 0.1440 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.7781 2.9925 . . 287 5549 100.00 . . . 0.1652 . 0.1465 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.9925 3.2935 . . 333 5534 100.00 . . . 0.1621 . 0.1449 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.2935 3.7696 . . 288 5604 100.00 . . . 0.1445 . 0.1367 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.7696 4.7478 . . 292 5598 100.00 . . . 0.1255 . 0.1208 . . . . . . . . . . 'X-RAY DIFFRACTION' 4.7478 37.1886 . . 304 5560 99.00 . . . 0.1712 . 0.1599 . . . . . . . . . . # _struct.entry_id 4Z80 _struct.title 'Crystal structure of Toxoplasma gondii AMA4 DI-DII-EGF1 in complex with a 33 aa TgRON2L1 peptide' _struct.pdbx_descriptor 'EGF family domain-containing protein' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 4Z80 _struct_keywords.text 'Apicomplexa, invasion, moving junction, parasite, PAN domain, MEMBRANE PROTEIN' _struct_keywords.pdbx_keywords 'MEMBRANE PROTEIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 1 ? D N N 2 ? E N N 3 ? F N N 3 ? G N N 3 ? H N N 4 ? I N N 4 ? J N N 4 ? K N N 5 ? L N N 3 ? M N N 6 ? N N N 6 ? O N N 6 ? P N N 6 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 SER A 7 ? ASP A 17 ? SER A 59 ASP A 69 1 ? 11 HELX_P HELX_P2 AA2 ASN A 20 ? HIS A 25 ? ASN A 72 HIS A 77 1 ? 6 HELX_P HELX_P3 AA3 ALA A 70 ? SER A 74 ? ALA A 122 SER A 126 5 ? 5 HELX_P HELX_P4 AA4 ILE A 79 ? VAL A 85 ? ILE A 131 VAL A 137 1 ? 7 HELX_P HELX_P5 AA5 THR A 115 ? ASN A 119 ? THR A 167 ASN A 171 5 ? 5 HELX_P HELX_P6 AA6 ALA A 145 ? GLU A 149 ? ALA A 197 GLU A 201 5 ? 5 HELX_P HELX_P7 AA7 ASN A 164 ? ASP A 171 ? ASN A 216 ASP A 223 1 ? 8 HELX_P HELX_P8 AA8 GLY A 251 ? THR A 263 ? GLY A 303 THR A 315 1 ? 13 HELX_P HELX_P9 AA9 HIS A 264 ? TRP A 266 ? HIS A 316 TRP A 318 5 ? 3 HELX_P HELX_P10 AB1 THR A 323 ? SER A 327 ? THR A 375 SER A 379 5 ? 5 HELX_P HELX_P11 AB2 ASP A 339 ? CYS A 344 ? ASP A 391 CYS A 396 1 ? 6 HELX_P HELX_P12 AB3 ALA A 378 ? LEU A 388 ? ALA A 430 LEU A 440 1 ? 11 HELX_P HELX_P13 AB4 GLU A 417 ? THR A 422 ? GLU A 469 THR A 474 5 ? 6 HELX_P HELX_P14 AB5 ASP A 453 ? ALA A 457 ? ASP A 505 ALA A 509 5 ? 5 HELX_P HELX_P15 AB6 ASP A 461 ? VAL A 465 ? ASP A 513 VAL A 517 5 ? 5 HELX_P HELX_P16 AB7 ASN B 9 ? SER B 18 ? ASN C 1296 SER C 1305 1 ? 10 HELX_P HELX_P17 AB8 THR C 8 ? ASP C 17 ? THR B 60 ASP B 69 1 ? 10 HELX_P HELX_P18 AB9 ASN C 20 ? HIS C 25 ? ASN B 72 HIS B 77 1 ? 6 HELX_P HELX_P19 AC1 ALA C 70 ? SER C 74 ? ALA B 122 SER B 126 5 ? 5 HELX_P HELX_P20 AC2 ILE C 79 ? VAL C 85 ? ILE B 131 VAL B 137 1 ? 7 HELX_P HELX_P21 AC3 THR C 115 ? ASN C 119 ? THR B 167 ASN B 171 5 ? 5 HELX_P HELX_P22 AC4 ALA C 145 ? GLU C 149 ? ALA B 197 GLU B 201 5 ? 5 HELX_P HELX_P23 AC5 ASN C 164 ? ASP C 171 ? ASN B 216 ASP B 223 1 ? 8 HELX_P HELX_P24 AC6 GLY C 251 ? THR C 263 ? GLY B 303 THR B 315 1 ? 13 HELX_P HELX_P25 AC7 HIS C 264 ? TRP C 266 ? HIS B 316 TRP B 318 5 ? 3 HELX_P HELX_P26 AC8 THR C 323 ? SER C 327 ? THR B 375 SER B 379 5 ? 5 HELX_P HELX_P27 AC9 ASP C 339 ? CYS C 344 ? ASP B 391 CYS B 396 1 ? 6 HELX_P HELX_P28 AD1 ALA C 378 ? LEU C 388 ? ALA B 430 LEU B 440 1 ? 11 HELX_P HELX_P29 AD2 GLU C 417 ? THR C 422 ? GLU B 469 THR B 474 5 ? 6 HELX_P HELX_P30 AD3 ASP C 453 ? ALA C 457 ? ASP B 505 ALA B 509 5 ? 5 HELX_P HELX_P31 AD4 ASP C 461 ? VAL C 465 ? ASP B 513 VAL B 517 5 ? 5 HELX_P HELX_P32 AD5 ASN D 9 ? SER D 18 ? ASN D 1296 SER D 1305 1 ? 10 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 72 SG ? ? ? 1_555 A CYS 274 SG ? ? A CYS 124 A CYS 326 1_555 ? ? ? ? ? ? ? 2.032 ? disulf2 disulf ? ? A CYS 95 SG ? ? ? 1_555 A CYS 344 SG ? ? A CYS 147 A CYS 396 1_555 ? ? ? ? ? ? ? 2.053 ? disulf3 disulf ? ? A CYS 133 SG ? ? ? 1_555 A CYS 231 SG ? ? A CYS 185 A CYS 283 1_555 ? ? ? ? ? ? ? 2.038 ? disulf4 disulf ? ? A CYS 161 SG ? ? ? 1_555 A CYS 265 SG ? ? A CYS 213 A CYS 317 1_555 ? ? ? ? ? ? ? 2.043 ? disulf5 disulf ? ? A CYS 183 SG ? ? ? 1_555 A CYS 261 SG ? ? A CYS 235 A CYS 313 1_555 ? ? ? ? ? ? ? 2.032 ? disulf6 disulf ? ? A CYS 255 SG ? ? ? 1_555 A CYS 289 SG ? ? A CYS 307 A CYS 341 1_555 ? ? ? ? ? ? ? 2.058 ? disulf7 disulf ? ? A CYS 304 SG ? ? ? 1_555 A CYS 317 SG ? ? A CYS 356 A CYS 369 1_555 ? ? ? ? ? ? ? 2.028 ? disulf8 disulf ? ? A CYS 364 SG ? ? ? 1_555 A CYS 436 SG ? ? A CYS 416 A CYS 488 1_555 ? ? ? ? ? ? ? 2.060 ? disulf9 disulf ? ? A CYS 381 SG ? ? ? 1_555 A CYS 427 SG A ? A CYS 433 A CYS 479 1_555 ? ? ? ? ? ? ? 2.040 ? disulf10 disulf ? ? A CYS 413 SG ? ? ? 1_555 A CYS 419 SG ? ? A CYS 465 A CYS 471 1_555 ? ? ? ? ? ? ? 2.041 ? disulf11 disulf ? ? B CYS 20 SG ? ? ? 1_555 B CYS 26 SG ? ? C CYS 1307 C CYS 1313 1_555 ? ? ? ? ? ? ? 2.030 ? disulf12 disulf ? ? C CYS 72 SG ? ? ? 1_555 C CYS 274 SG ? ? B CYS 124 B CYS 326 1_555 ? ? ? ? ? ? ? 2.026 ? disulf13 disulf ? ? C CYS 95 SG ? ? ? 1_555 C CYS 344 SG ? ? B CYS 147 B CYS 396 1_555 ? ? ? ? ? ? ? 2.061 ? disulf14 disulf ? ? C CYS 133 SG ? ? ? 1_555 C CYS 231 SG ? ? B CYS 185 B CYS 283 1_555 ? ? ? ? ? ? ? 2.043 ? disulf15 disulf ? ? C CYS 161 SG ? ? ? 1_555 C CYS 265 SG ? ? B CYS 213 B CYS 317 1_555 ? ? ? ? ? ? ? 2.041 ? disulf16 disulf ? ? C CYS 183 SG ? ? ? 1_555 C CYS 261 SG ? ? B CYS 235 B CYS 313 1_555 ? ? ? ? ? ? ? 2.032 ? disulf17 disulf ? ? C CYS 255 SG ? ? ? 1_555 C CYS 289 SG ? ? B CYS 307 B CYS 341 1_555 ? ? ? ? ? ? ? 2.055 ? disulf18 disulf ? ? C CYS 304 SG ? ? ? 1_555 C CYS 317 SG ? ? B CYS 356 B CYS 369 1_555 ? ? ? ? ? ? ? 2.024 ? disulf19 disulf ? ? C CYS 364 SG ? ? ? 1_555 C CYS 436 SG ? ? B CYS 416 B CYS 488 1_555 ? ? ? ? ? ? ? 2.056 ? disulf20 disulf ? ? C CYS 381 SG ? ? ? 1_555 C CYS 427 SG A ? B CYS 433 B CYS 479 1_555 ? ? ? ? ? ? ? 2.044 ? disulf21 disulf ? ? C CYS 413 SG ? ? ? 1_555 C CYS 419 SG ? ? B CYS 465 B CYS 471 1_555 ? ? ? ? ? ? ? 2.045 ? disulf22 disulf ? ? D CYS 20 SG ? ? ? 1_555 D CYS 26 SG ? ? D CYS 1307 D CYS 1313 1_555 ? ? ? ? ? ? ? 2.030 ? covale1 covale one ? C ASN 375 ND2 ? ? ? 1_555 K NAG . C1 ? ? B ASN 427 B NAG 601 1_555 ? ? ? ? ? ? ? 1.293 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 MET 126 A . ? MET 178 A PRO 127 A ? PRO 179 A 1 1.37 2 CYS 161 A . ? CYS 213 A PRO 162 A ? PRO 214 A 1 -1.58 3 PRO 232 A . ? PRO 284 A PRO 233 A ? PRO 285 A 1 0.62 4 PRO 236 A . ? PRO 288 A PRO 237 A ? PRO 289 A 1 0.90 5 PRO 21 B . ? PRO 1308 C PRO 22 B ? PRO 1309 C 1 3.37 6 MET 126 C . ? MET 178 B PRO 127 C ? PRO 179 B 1 2.06 7 CYS 161 C . ? CYS 213 B PRO 162 C ? PRO 214 B 1 -1.19 8 PRO 232 C . ? PRO 284 B PRO 233 C ? PRO 285 B 1 0.95 9 PRO 236 C . ? PRO 288 B PRO 237 C ? PRO 289 B 1 -1.66 10 PRO 21 D . ? PRO 1308 D PRO 22 D ? PRO 1309 D 1 0.99 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 3 ? AA2 ? 2 ? AA3 ? 4 ? AA4 ? 2 ? AA5 ? 2 ? AA6 ? 2 ? AA7 ? 2 ? AA8 ? 6 ? AA9 ? 3 ? AB1 ? 2 ? AB2 ? 4 ? AB3 ? 2 ? AB4 ? 2 ? AB5 ? 2 ? AB6 ? 2 ? AB7 ? 6 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? anti-parallel AA2 1 2 ? anti-parallel AA3 1 2 ? anti-parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA4 1 2 ? anti-parallel AA5 1 2 ? anti-parallel AA6 1 2 ? anti-parallel AA7 1 2 ? anti-parallel AA8 1 2 ? anti-parallel AA8 2 3 ? anti-parallel AA8 3 4 ? anti-parallel AA8 4 5 ? anti-parallel AA8 5 6 ? anti-parallel AA9 1 2 ? anti-parallel AA9 2 3 ? anti-parallel AB1 1 2 ? anti-parallel AB2 1 2 ? anti-parallel AB2 2 3 ? anti-parallel AB2 3 4 ? anti-parallel AB3 1 2 ? anti-parallel AB4 1 2 ? anti-parallel AB5 1 2 ? anti-parallel AB6 1 2 ? anti-parallel AB7 1 2 ? anti-parallel AB7 2 3 ? anti-parallel AB7 3 4 ? anti-parallel AB7 4 5 ? anti-parallel AB7 5 6 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 ASP A 27 ? TRP A 30 ? ASP A 79 TRP A 82 AA1 2 THR A 43 ? LYS A 51 ? THR A 95 LYS A 103 AA1 3 LYS A 36 ? ARG A 40 ? LYS A 88 ARG A 92 AA2 1 TYR A 60 ? GLU A 62 ? TYR A 112 GLU A 114 AA2 2 TYR A 89 ? ALA A 91 ? TYR A 141 ALA A 143 AA3 1 ASN A 97 ? TYR A 98 ? ASN A 149 TYR A 150 AA3 2 MET A 329 ? VAL A 332 ? MET A 381 VAL A 384 AA3 3 ALA A 280 ? ASP A 283 ? ALA A 332 ASP A 335 AA3 4 CYS A 289 ? LEU A 291 ? CYS A 341 LEU A 343 AA4 1 VAL A 101 ? PHE A 104 ? VAL A 153 PHE A 156 AA4 2 VAL A 318 ? MET A 321 ? VAL A 370 MET A 373 AA5 1 HIS A 160 ? CYS A 161 ? HIS A 212 CYS A 213 AA5 2 LEU A 192 ? ARG A 193 ? LEU A 244 ARG A 245 AA6 1 LEU A 195 ? ASP A 196 ? LEU A 247 ASP A 248 AA6 2 THR A 207 ? GLU A 208 ? THR A 259 GLU A 260 AA7 1 LYS A 218 ? GLY A 219 ? LYS A 270 GLY A 271 AA7 2 HIS A 238 ? VAL A 239 ? HIS A 290 VAL A 291 AA8 1 TYR A 363 ? PRO A 366 ? TYR A 415 PRO A 418 AA8 2 LEU A 350 ? SER A 359 ? LEU A 402 SER A 411 AA8 3 CYS A 436 ? THR A 447 ? CYS A 488 THR A 499 AA8 4 TRP A 405 ? ALA A 410 ? TRP A 457 ALA A 462 AA8 5 ARG A 424 ? TYR A 430 ? ARG A 476 TYR A 482 AA8 6 ALA A 371 ? THR A 377 ? ALA A 423 THR A 429 AA9 1 ASP C 27 ? TRP C 30 ? ASP B 79 TRP B 82 AA9 2 THR C 43 ? LYS C 51 ? THR B 95 LYS B 103 AA9 3 LYS C 36 ? ARG C 40 ? LYS B 88 ARG B 92 AB1 1 TYR C 60 ? GLU C 62 ? TYR B 112 GLU B 114 AB1 2 TYR C 89 ? ALA C 91 ? TYR B 141 ALA B 143 AB2 1 ASN C 97 ? TYR C 98 ? ASN B 149 TYR B 150 AB2 2 MET C 329 ? VAL C 332 ? MET B 381 VAL B 384 AB2 3 ALA C 280 ? ASP C 283 ? ALA B 332 ASP B 335 AB2 4 CYS C 289 ? LEU C 291 ? CYS B 341 LEU B 343 AB3 1 VAL C 101 ? PHE C 104 ? VAL B 153 PHE B 156 AB3 2 VAL C 318 ? MET C 321 ? VAL B 370 MET B 373 AB4 1 HIS C 160 ? CYS C 161 ? HIS B 212 CYS B 213 AB4 2 LEU C 192 ? ARG C 193 ? LEU B 244 ARG B 245 AB5 1 LEU C 195 ? ASP C 196 ? LEU B 247 ASP B 248 AB5 2 THR C 207 ? GLU C 208 ? THR B 259 GLU B 260 AB6 1 LYS C 218 ? GLY C 219 ? LYS B 270 GLY B 271 AB6 2 HIS C 238 ? VAL C 239 ? HIS B 290 VAL B 291 AB7 1 TYR C 363 ? PRO C 366 ? TYR B 415 PRO B 418 AB7 2 LEU C 350 ? SER C 359 ? LEU B 402 SER B 411 AB7 3 CYS C 436 ? THR C 447 ? CYS B 488 THR B 499 AB7 4 TRP C 405 ? ALA C 410 ? TRP B 457 ALA B 462 AB7 5 ARG C 424 ? TYR C 430 ? ARG B 476 TYR B 482 AB7 6 ALA C 371 ? THR C 377 ? ALA B 423 THR B 429 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N ASP A 27 ? N ASP A 79 O ARG A 50 ? O ARG A 102 AA1 2 3 O TYR A 45 ? O TYR A 97 N HIS A 38 ? N HIS A 90 AA2 1 2 N SER A 61 ? N SER A 113 O MET A 90 ? O MET A 142 AA3 1 2 N ASN A 97 ? N ASN A 149 O TYR A 331 ? O TYR A 383 AA3 2 3 O VAL A 332 ? O VAL A 384 N ALA A 280 ? N ALA A 332 AA3 3 4 N MET A 281 ? N MET A 333 O ARG A 290 ? O ARG A 342 AA4 1 2 N ALA A 103 ? N ALA A 155 O ARG A 319 ? O ARG A 371 AA5 1 2 N CYS A 161 ? N CYS A 213 O LEU A 192 ? O LEU A 244 AA6 1 2 N ASP A 196 ? N ASP A 248 O THR A 207 ? O THR A 259 AA7 1 2 N GLY A 219 ? N GLY A 271 O HIS A 238 ? O HIS A 290 AA8 1 2 O LYS A 365 ? O LYS A 417 N VAL A 357 ? N VAL A 409 AA8 2 3 N LEU A 350 ? N LEU A 402 O ALA A 445 ? O ALA A 497 AA8 3 4 O MET A 444 ? O MET A 496 N PHE A 408 ? N PHE A 460 AA8 4 5 N VAL A 409 ? N VAL A 461 O LYS A 426 ? O LYS A 478 AA8 5 6 O CYS A 427 ? O CYS A 479 N LEU A 373 ? N LEU A 425 AA9 1 2 N ASP C 27 ? N ASP B 79 O LYS C 51 ? O LYS B 103 AA9 2 3 O TYR C 45 ? O TYR B 97 N HIS C 38 ? N HIS B 90 AB1 1 2 N SER C 61 ? N SER B 113 O MET C 90 ? O MET B 142 AB2 1 2 N ASN C 97 ? N ASN B 149 O TYR C 331 ? O TYR B 383 AB2 2 3 O VAL C 332 ? O VAL B 384 N ALA C 280 ? N ALA B 332 AB2 3 4 N MET C 281 ? N MET B 333 O ARG C 290 ? O ARG B 342 AB3 1 2 N ALA C 103 ? N ALA B 155 O ARG C 319 ? O ARG B 371 AB4 1 2 N CYS C 161 ? N CYS B 213 O LEU C 192 ? O LEU B 244 AB5 1 2 N ASP C 196 ? N ASP B 248 O THR C 207 ? O THR B 259 AB6 1 2 N GLY C 219 ? N GLY B 271 O HIS C 238 ? O HIS B 290 AB7 1 2 O TYR C 363 ? O TYR B 415 N SER C 359 ? N SER B 411 AB7 2 3 N LEU C 350 ? N LEU B 402 O ALA C 445 ? O ALA B 497 AB7 3 4 O MET C 444 ? O MET B 496 N PHE C 408 ? N PHE B 460 AB7 4 5 N VAL C 409 ? N VAL B 461 O LYS C 426 ? O LYS B 478 AB7 5 6 O CYS C 427 ? O CYS B 479 N LEU C 373 ? N LEU B 425 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A GOL 601 ? 6 'binding site for residue GOL A 601' AC2 Software A GOL 602 ? 6 'binding site for residue GOL A 602' AC3 Software A GOL 603 ? 5 'binding site for residue GOL A 603' AC4 Software A SO4 604 ? 7 'binding site for residue SO4 A 604' AC5 Software A SO4 605 ? 9 'binding site for residue SO4 A 605' AC6 Software A SO4 606 ? 6 'binding site for residue SO4 A 606' AC7 Software B GOL 602 ? 7 'binding site for residue GOL B 602' AC8 Software B NAG 601 ? 4 'binding site for Mono-Saccharide NAG B 601 bound to ASN B 427' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 6 VAL A 182 ? VAL A 234 . ? 1_555 ? 2 AC1 6 ASN A 184 ? ASN A 236 . ? 1_555 ? 3 AC1 6 TRP A 248 ? TRP A 300 . ? 1_555 ? 4 AC1 6 HOH M . ? HOH A 735 . ? 1_555 ? 5 AC1 6 HOH M . ? HOH A 736 . ? 1_555 ? 6 AC1 6 HOH M . ? HOH A 931 . ? 1_555 ? 7 AC2 6 ARG A 354 ? ARG A 406 . ? 1_555 ? 8 AC2 6 PRO A 366 ? PRO A 418 . ? 1_555 ? 9 AC2 6 MET A 367 ? MET A 419 . ? 1_555 ? 10 AC2 6 PHE A 428 ? PHE A 480 . ? 1_555 ? 11 AC2 6 TYR A 430 ? TYR A 482 . ? 1_555 ? 12 AC2 6 HOH M . ? HOH A 1011 . ? 1_555 ? 13 AC3 5 SER A 397 ? SER A 449 . ? 1_555 ? 14 AC3 5 SER A 398 ? SER A 450 . ? 1_555 ? 15 AC3 5 SO4 J . ? SO4 A 606 . ? 1_555 ? 16 AC3 5 HOH M . ? HOH A 884 . ? 1_555 ? 17 AC3 5 ASP C 108 ? ASP B 160 . ? 5_565 ? 18 AC4 7 ARG A 384 ? ARG A 436 . ? 1_555 ? 19 AC4 7 MET A 387 ? MET A 439 . ? 1_555 ? 20 AC4 7 HOH M . ? HOH A 711 . ? 1_555 ? 21 AC4 7 HOH M . ? HOH A 889 . ? 1_555 ? 22 AC4 7 HOH M . ? HOH A 1079 . ? 1_555 ? 23 AC4 7 HOH M . ? HOH A 1102 . ? 1_555 ? 24 AC4 7 ARG C 401 ? ARG B 453 . ? 5_565 ? 25 AC5 9 LYS A 106 ? LYS A 158 . ? 1_555 ? 26 AC5 9 ARG A 111 ? ARG A 163 . ? 1_555 ? 27 AC5 9 HOH M . ? HOH A 728 . ? 1_555 ? 28 AC5 9 HOH M . ? HOH A 850 . ? 1_555 ? 29 AC5 9 HOH M . ? HOH A 907 . ? 1_555 ? 30 AC5 9 HOH M . ? HOH A 912 . ? 1_555 ? 31 AC5 9 HOH M . ? HOH A 1157 . ? 1_555 ? 32 AC5 9 VAL C 239 ? VAL B 291 . ? 3_575 ? 33 AC5 9 HOH O . ? HOH B 776 . ? 3_575 ? 34 AC6 6 ARG A 401 ? ARG A 453 . ? 1_555 ? 35 AC6 6 GOL G . ? GOL A 603 . ? 1_555 ? 36 AC6 6 HOH M . ? HOH A 910 . ? 1_555 ? 37 AC6 6 HOH M . ? HOH A 1098 . ? 1_555 ? 38 AC6 6 ARG C 384 ? ARG B 436 . ? 5_565 ? 39 AC6 6 MET C 387 ? MET B 439 . ? 5_565 ? 40 AC7 7 ARG C 354 ? ARG B 406 . ? 1_555 ? 41 AC7 7 PRO C 366 ? PRO B 418 . ? 1_555 ? 42 AC7 7 MET C 367 ? MET B 419 . ? 1_555 ? 43 AC7 7 PHE C 428 ? PHE B 480 . ? 1_555 ? 44 AC7 7 TYR C 430 ? TYR B 482 . ? 1_555 ? 45 AC7 7 HOH O . ? HOH B 841 . ? 1_555 ? 46 AC7 7 HOH O . ? HOH B 876 . ? 1_555 ? 47 AC8 4 ASN C 375 ? ASN B 427 . ? 1_555 ? 48 AC8 4 ARG C 424 ? ARG B 476 . ? 1_555 ? 49 AC8 4 HOH O . ? HOH B 703 . ? 1_555 ? 50 AC8 4 HOH O . ? HOH B 1029 . ? 1_555 ? # _atom_sites.entry_id 4Z80 _atom_sites.fract_transf_matrix[1][1] 0.008295 _atom_sites.fract_transf_matrix[1][2] 0.004789 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009578 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007058 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . SER A 1 7 ? 19.278 130.882 -16.110 1.00 44.97 ? 59 SER A N 1 ATOM 2 C CA . SER A 1 7 ? 20.560 131.120 -15.451 1.00 36.30 ? 59 SER A CA 1 ATOM 3 C C . SER A 1 7 ? 20.367 131.569 -14.009 1.00 32.17 ? 59 SER A C 1 ATOM 4 O O . SER A 1 7 ? 19.738 132.600 -13.742 1.00 24.50 ? 59 SER A O 1 ATOM 5 C CB . SER A 1 7 ? 21.370 132.169 -16.214 1.00 45.20 ? 59 SER A CB 1 ATOM 6 O OG . SER A 1 7 ? 22.413 132.697 -15.406 1.00 35.68 ? 59 SER A OG 1 ATOM 7 N N . THR A 1 8 ? 20.911 130.789 -13.081 1.00 26.16 ? 60 THR A N 1 ATOM 8 C CA . THR A 1 8 ? 20.808 131.118 -11.671 1.00 22.32 ? 60 THR A CA 1 ATOM 9 C C . THR A 1 8 ? 21.525 132.427 -11.353 1.00 21.31 ? 60 THR A C 1 ATOM 10 O O . THR A 1 8 ? 21.043 133.193 -10.535 1.00 17.93 ? 60 THR A O 1 ATOM 11 C CB . THR A 1 8 ? 21.386 130.010 -10.787 1.00 23.21 ? 60 THR A CB 1 ATOM 12 O OG1 . THR A 1 8 ? 22.689 129.655 -11.265 1.00 27.12 ? 60 THR A OG1 1 ATOM 13 C CG2 . THR A 1 8 ? 20.487 128.783 -10.815 1.00 25.24 ? 60 THR A CG2 1 ATOM 14 N N . SER A 1 9 ? 22.664 132.688 -11.994 1.00 20.97 ? 61 SER A N 1 ATOM 15 C CA . SER A 1 9 ? 23.409 133.917 -11.709 1.00 21.42 ? 61 SER A CA 1 ATOM 16 C C . SER A 1 9 ? 22.582 135.153 -12.077 1.00 20.30 ? 61 SER A C 1 ATOM 17 O O . SER A 1 9 ? 22.568 136.140 -11.337 1.00 17.20 ? 61 SER A O 1 ATOM 18 C CB . SER A 1 9 ? 24.752 133.935 -12.449 1.00 22.64 ? 61 SER A CB 1 ATOM 19 O OG . SER A 1 9 ? 24.577 134.069 -13.846 1.00 33.60 ? 61 SER A OG 1 ATOM 20 N N . THR A 1 10 ? 21.888 135.094 -13.210 1.00 19.85 ? 62 THR A N 1 ATOM 21 C CA . THR A 1 10 ? 21.010 136.180 -13.631 1.00 19.98 ? 62 THR A CA 1 ATOM 22 C C . THR A 1 10 ? 19.822 136.319 -12.685 1.00 19.97 ? 62 THR A C 1 ATOM 23 O O . THR A 1 10 ? 19.453 137.427 -12.290 1.00 17.36 ? 62 THR A O 1 ATOM 24 C CB . THR A 1 10 ? 20.511 135.959 -15.065 1.00 26.51 ? 62 THR A CB 1 ATOM 25 O OG1 . THR A 1 10 ? 21.636 135.956 -15.953 1.00 29.87 ? 62 THR A OG1 1 ATOM 26 C CG2 . THR A 1 10 ? 19.540 137.059 -15.493 1.00 31.06 ? 62 THR A CG2 1 ATOM 27 N N . SER A 1 11 ? 19.223 135.197 -12.309 1.00 17.31 ? 63 SER A N 1 ATOM 28 C CA . SER A 1 11 ? 18.097 135.232 -11.394 1.00 16.28 ? 63 SER A CA 1 ATOM 29 C C . SER A 1 11 ? 18.505 135.770 -10.033 1.00 12.95 ? 63 SER A C 1 ATOM 30 O O . SER A 1 11 ? 17.739 136.491 -9.396 1.00 14.72 ? 63 SER A O 1 ATOM 31 C CB . SER A 1 11 ? 17.493 133.841 -11.240 1.00 20.23 ? 63 SER A CB 1 ATOM 32 O OG . SER A 1 11 ? 16.842 133.459 -12.437 1.00 21.37 ? 63 SER A OG 1 ATOM 33 N N . ARG A 1 12 ? 19.710 135.422 -9.598 1.00 14.52 ? 64 ARG A N 1 ATOM 34 C CA . ARG A 1 12 ? 20.236 135.904 -8.330 1.00 14.00 ? 64 ARG A CA 1 ATOM 35 C C . ARG A 1 12 ? 20.401 137.420 -8.364 1.00 15.02 ? 64 ARG A C 1 ATOM 36 O O . ARG A 1 12 ? 20.017 138.114 -7.425 1.00 14.10 ? 64 ARG A O 1 ATOM 37 C CB . ARG A 1 12 ? 21.572 135.231 -8.011 1.00 13.86 ? 64 ARG A CB 1 ATOM 38 C CG . ARG A 1 12 ? 22.275 135.767 -6.766 1.00 15.99 ? 64 ARG A CG 1 ATOM 39 C CD . ARG A 1 12 ? 23.458 134.906 -6.364 1.00 18.58 ? 64 ARG A CD 1 ATOM 40 N NE . ARG A 1 12 ? 23.053 133.505 -6.264 1.00 23.58 ? 64 ARG A NE 1 ATOM 41 C CZ . ARG A 1 12 ? 23.363 132.549 -7.138 1.00 30.48 ? 64 ARG A CZ 1 ATOM 42 N NH1 . ARG A 1 12 ? 24.134 132.801 -8.193 1.00 28.33 ? 64 ARG A NH1 1 ATOM 43 N NH2 . ARG A 1 12 ? 22.908 131.319 -6.941 1.00 32.68 ? 64 ARG A NH2 1 ATOM 44 N N . ALA A 1 13 ? 20.976 137.928 -9.448 1.00 15.29 ? 65 ALA A N 1 ATOM 45 C CA . ALA A 1 13 ? 21.164 139.373 -9.590 1.00 15.94 ? 65 ALA A CA 1 ATOM 46 C C . ALA A 1 13 ? 19.820 140.098 -9.602 1.00 16.35 ? 65 ALA A C 1 ATOM 47 O O . ALA A 1 13 ? 19.662 141.150 -8.974 1.00 14.64 ? 65 ALA A O 1 ATOM 48 C CB . ALA A 1 13 ? 21.951 139.686 -10.860 1.00 17.95 ? 65 ALA A CB 1 ATOM 49 N N . THR A 1 14 ? 18.839 139.537 -10.299 1.00 13.31 ? 66 THR A N 1 ATOM 50 C CA . THR A 1 14 ? 17.509 140.142 -10.362 1.00 14.50 ? 66 THR A CA 1 ATOM 51 C C . THR A 1 14 ? 16.880 140.216 -8.974 1.00 15.71 ? 66 THR A C 1 ATOM 52 O O . THR A 1 14 ? 16.293 141.237 -8.610 1.00 16.28 ? 66 THR A O 1 ATOM 53 C CB . THR A 1 14 ? 16.590 139.355 -11.313 1.00 19.99 ? 66 THR A CB 1 ATOM 54 O OG1 . THR A 1 14 ? 17.065 139.515 -12.655 1.00 20.78 ? 66 THR A OG1 1 ATOM 55 C CG2 . THR A 1 14 ? 15.149 139.841 -11.238 1.00 19.05 ? 66 THR A CG2 1 ATOM 56 N N . TYR A 1 15 ? 17.013 139.145 -8.198 1.00 13.21 ? 67 TYR A N 1 ATOM 57 C CA . TYR A 1 15 ? 16.485 139.121 -6.841 1.00 12.10 ? 67 TYR A CA 1 ATOM 58 C C . TYR A 1 15 ? 17.224 140.119 -5.946 1.00 13.21 ? 67 TYR A C 1 ATOM 59 O O . TYR A 1 15 ? 16.595 140.892 -5.223 1.00 12.24 ? 67 TYR A O 1 ATOM 60 C CB . TYR A 1 15 ? 16.571 137.708 -6.240 1.00 12.72 ? 67 TYR A CB 1 ATOM 61 C CG . TYR A 1 15 ? 16.255 137.672 -4.754 1.00 12.55 ? 67 TYR A CG 1 ATOM 62 C CD1 . TYR A 1 15 ? 14.948 137.763 -4.299 1.00 14.39 ? 67 TYR A CD1 1 ATOM 63 C CD2 . TYR A 1 15 ? 17.269 137.572 -3.813 1.00 11.69 ? 67 TYR A CD2 1 ATOM 64 C CE1 . TYR A 1 15 ? 14.658 137.751 -2.931 1.00 16.80 ? 67 TYR A CE1 1 ATOM 65 C CE2 . TYR A 1 15 ? 16.990 137.552 -2.452 1.00 14.05 ? 67 TYR A CE2 1 ATOM 66 C CZ . TYR A 1 15 ? 15.688 137.648 -2.021 1.00 14.17 ? 67 TYR A CZ 1 ATOM 67 O OH . TYR A 1 15 ? 15.435 137.626 -0.663 1.00 18.47 ? 67 TYR A OH 1 ATOM 68 N N . MET A 1 16 ? 18.552 140.108 -5.997 1.00 14.46 ? 68 MET A N 1 ATOM 69 C CA . MET A 1 16 ? 19.350 140.927 -5.081 1.00 11.82 ? 68 MET A CA 1 ATOM 70 C C . MET A 1 16 ? 19.230 142.419 -5.365 1.00 13.63 ? 68 MET A C 1 ATOM 71 O O . MET A 1 16 ? 19.578 143.235 -4.512 1.00 13.41 ? 68 MET A O 1 ATOM 72 C CB . MET A 1 16 ? 20.820 140.502 -5.132 1.00 14.07 ? 68 MET A CB 1 ATOM 73 C CG . MET A 1 16 ? 21.082 139.154 -4.467 1.00 12.94 ? 68 MET A CG 1 ATOM 74 S SD . MET A 1 16 ? 20.695 139.099 -2.720 1.00 14.33 ? 68 MET A SD 1 ATOM 75 C CE . MET A 1 16 ? 21.890 140.264 -2.050 1.00 12.54 ? 68 MET A CE 1 ATOM 76 N N . ASP A 1 17 ? 18.717 142.766 -6.543 1.00 12.74 ? 69 ASP A N 1 ATOM 77 C CA . ASP A 1 17 ? 18.448 144.158 -6.909 1.00 14.87 ? 69 ASP A CA 1 ATOM 78 C C . ASP A 1 17 ? 17.560 144.842 -5.867 1.00 14.50 ? 69 ASP A C 1 ATOM 79 O O . ASP A 1 17 ? 17.666 146.053 -5.658 1.00 14.35 ? 69 ASP A O 1 ATOM 80 C CB . ASP A 1 17 ? 17.804 144.194 -8.303 1.00 15.41 ? 69 ASP A CB 1 ATOM 81 C CG . ASP A 1 17 ? 17.491 145.595 -8.798 1.00 19.92 ? 69 ASP A CG 1 ATOM 82 O OD1 . ASP A 1 17 ? 18.320 146.513 -8.639 1.00 18.09 ? 69 ASP A OD1 1 ATOM 83 O OD2 . ASP A 1 17 ? 16.404 145.757 -9.390 1.00 20.47 ? 69 ASP A OD2 1 ATOM 84 N N . ARG A 1 18 ? 16.717 144.074 -5.174 1.00 11.45 ? 70 ARG A N 1 ATOM 85 C CA . ARG A 1 18 ? 15.789 144.666 -4.213 1.00 11.53 ? 70 ARG A CA 1 ATOM 86 C C . ARG A 1 18 ? 16.526 145.234 -2.992 1.00 10.69 ? 70 ARG A C 1 ATOM 87 O O . ARG A 1 18 ? 15.930 145.967 -2.198 1.00 11.14 ? 70 ARG A O 1 ATOM 88 C CB . ARG A 1 18 ? 14.720 143.647 -3.770 1.00 12.72 ? 70 ARG A CB 1 ATOM 89 C CG . ARG A 1 18 ? 15.214 142.548 -2.827 1.00 12.35 ? 70 ARG A CG 1 ATOM 90 C CD . ARG A 1 18 ? 14.191 141.407 -2.693 1.00 15.97 ? 70 ARG A CD 1 ATOM 91 N NE . ARG A 1 18 ? 13.784 140.944 -4.015 1.00 13.52 ? 70 ARG A NE 1 ATOM 92 C CZ . ARG A 1 18 ? 12.641 140.315 -4.283 1.00 15.62 ? 70 ARG A CZ 1 ATOM 93 N NH1 . ARG A 1 18 ? 11.777 140.042 -3.315 1.00 15.83 ? 70 ARG A NH1 1 ATOM 94 N NH2 . ARG A 1 18 ? 12.368 139.960 -5.528 1.00 16.12 ? 70 ARG A NH2 1 ATOM 95 N N . PHE A 1 19 ? 17.810 144.913 -2.853 1.00 12.40 ? 71 PHE A N 1 ATOM 96 C CA . PHE A 1 19 ? 18.601 145.389 -1.715 1.00 10.40 ? 71 PHE A CA 1 ATOM 97 C C . PHE A 1 19 ? 19.527 146.537 -2.115 1.00 11.57 ? 71 PHE A C 1 ATOM 98 O O . PHE A 1 19 ? 20.290 147.030 -1.279 1.00 13.29 ? 71 PHE A O 1 ATOM 99 C CB . PHE A 1 19 ? 19.403 144.233 -1.097 1.00 12.37 ? 71 PHE A CB 1 ATOM 100 C CG . PHE A 1 19 ? 18.532 143.111 -0.597 1.00 12.07 ? 71 PHE A CG 1 ATOM 101 C CD1 . PHE A 1 19 ? 17.703 143.294 0.493 1.00 12.50 ? 71 PHE A CD1 1 ATOM 102 C CD2 . PHE A 1 19 ? 18.519 141.891 -1.248 1.00 13.54 ? 71 PHE A CD2 1 ATOM 103 C CE1 . PHE A 1 19 ? 16.878 142.263 0.944 1.00 13.57 ? 71 PHE A CE1 1 ATOM 104 C CE2 . PHE A 1 19 ? 17.702 140.863 -0.800 1.00 14.08 ? 71 PHE A CE2 1 ATOM 105 C CZ . PHE A 1 19 ? 16.886 141.056 0.293 1.00 13.84 ? 71 PHE A CZ 1 ATOM 106 N N . ASN A 1 20 ? 19.439 146.996 -3.365 1.00 11.83 ? 72 ASN A N 1 ATOM 107 C CA . ASN A 1 20 ? 20.288 148.100 -3.827 1.00 12.78 ? 72 ASN A CA 1 ATOM 108 C C . ASN A 1 20 ? 19.637 149.441 -3.513 1.00 12.04 ? 72 ASN A C 1 ATOM 109 O O . ASN A 1 20 ? 19.071 150.113 -4.381 1.00 11.55 ? 72 ASN A O 1 ATOM 110 C CB . ASN A 1 20 ? 20.589 147.992 -5.321 1.00 10.82 ? 72 ASN A CB 1 ATOM 111 C CG . ASN A 1 20 ? 21.688 148.932 -5.753 1.00 13.09 ? 72 ASN A CG 1 ATOM 112 O OD1 . ASN A 1 20 ? 22.049 149.843 -5.011 1.00 13.88 ? 72 ASN A OD1 1 ATOM 113 N ND2 . ASN A 1 20 ? 22.227 148.721 -6.945 1.00 15.24 ? 72 ASN A ND2 1 ATOM 114 N N . ILE A 1 21 ? 19.753 149.834 -2.253 1.00 12.19 ? 73 ILE A N 1 ATOM 115 C CA . ILE A 1 21 ? 18.993 150.957 -1.722 1.00 11.19 ? 73 ILE A CA 1 ATOM 116 C C . ILE A 1 21 ? 19.370 152.292 -2.368 1.00 12.22 ? 73 ILE A C 1 ATOM 117 O O . ILE A 1 21 ? 18.487 153.035 -2.764 1.00 11.77 ? 73 ILE A O 1 ATOM 118 C CB . ILE A 1 21 ? 19.141 150.997 -0.181 1.00 11.37 ? 73 ILE A CB 1 ATOM 119 C CG1 . ILE A 1 21 ? 18.340 149.832 0.419 1.00 12.81 ? 73 ILE A CG1 1 ATOM 120 C CG2 . ILE A 1 21 ? 18.642 152.329 0.405 1.00 12.99 ? 73 ILE A CG2 1 ATOM 121 C CD1 . ILE A 1 21 ? 18.545 149.623 1.898 1.00 12.96 ? 73 ILE A CD1 1 ATOM 122 N N . PRO A 1 22 ? 20.674 152.600 -2.517 1.00 10.98 ? 74 PRO A N 1 ATOM 123 C CA . PRO A 1 22 ? 20.959 153.890 -3.168 1.00 13.42 ? 74 PRO A CA 1 ATOM 124 C C . PRO A 1 22 ? 20.446 153.989 -4.605 1.00 13.15 ? 74 PRO A C 1 ATOM 125 O O . PRO A 1 22 ? 20.019 155.059 -5.031 1.00 13.76 ? 74 PRO A O 1 ATOM 126 C CB . PRO A 1 22 ? 22.490 153.970 -3.118 1.00 14.24 ? 74 PRO A CB 1 ATOM 127 C CG . PRO A 1 22 ? 22.857 153.156 -1.925 1.00 14.02 ? 74 PRO A CG 1 ATOM 128 C CD . PRO A 1 22 ? 21.900 151.978 -1.994 1.00 13.83 ? 74 PRO A CD 1 ATOM 129 N N . LYS A 1 23 ? 20.461 152.886 -5.341 1.00 12.09 ? 75 LYS A N 1 ATOM 130 C CA . LYS A 1 23 ? 19.993 152.904 -6.726 1.00 14.03 ? 75 LYS A CA 1 ATOM 131 C C . LYS A 1 23 ? 18.466 153.001 -6.828 1.00 13.24 ? 75 LYS A C 1 ATOM 132 O O . LYS A 1 23 ? 17.942 153.627 -7.750 1.00 13.76 ? 75 LYS A O 1 ATOM 133 C CB . LYS A 1 23 ? 20.480 151.651 -7.461 1.00 14.36 ? 75 LYS A CB 1 ATOM 134 C CG . LYS A 1 23 ? 20.177 151.642 -8.962 1.00 15.81 ? 75 LYS A CG 1 ATOM 135 C CD . LYS A 1 23 ? 20.771 150.416 -9.623 1.00 19.69 ? 75 LYS A CD 1 ATOM 136 C CE . LYS A 1 23 ? 20.747 150.525 -11.140 1.00 25.58 ? 75 LYS A CE 1 ATOM 137 N NZ . LYS A 1 23 ? 19.383 150.358 -11.708 1.00 29.55 ? 75 LYS A NZ 1 ATOM 138 N N . ASN A 1 24 ? 17.756 152.386 -5.884 1.00 12.27 ? 76 ASN A N 1 ATOM 139 C CA . ASN A 1 24 ? 16.312 152.198 -6.017 1.00 12.44 ? 76 ASN A CA 1 ATOM 140 C C . ASN A 1 24 ? 15.454 153.063 -5.100 1.00 13.13 ? 76 ASN A C 1 ATOM 141 O O . ASN A 1 24 ? 14.288 153.279 -5.391 1.00 12.35 ? 76 ASN A O 1 ATOM 142 C CB . ASN A 1 24 ? 15.986 150.721 -5.792 1.00 11.44 ? 76 ASN A CB 1 ATOM 143 C CG . ASN A 1 24 ? 16.606 149.840 -6.858 1.00 14.47 ? 76 ASN A CG 1 ATOM 144 O OD1 . ASN A 1 24 ? 16.932 150.314 -7.946 1.00 16.40 ? 76 ASN A OD1 1 ATOM 145 N ND2 . ASN A 1 24 ? 16.786 148.571 -6.554 1.00 13.24 ? 76 ASN A ND2 1 ATOM 146 N N . HIS A 1 25 ? 16.039 153.577 -4.020 1.00 11.53 ? 77 HIS A N 1 ATOM 147 C CA . HIS A 1 25 ? 15.335 154.489 -3.129 1.00 9.73 ? 77 HIS A CA 1 ATOM 148 C C . HIS A 1 25 ? 15.464 155.890 -3.707 1.00 12.28 ? 77 HIS A C 1 ATOM 149 O O . HIS A 1 25 ? 16.261 156.721 -3.248 1.00 12.78 ? 77 HIS A O 1 ATOM 150 C CB . HIS A 1 25 ? 15.899 154.404 -1.712 1.00 13.02 ? 77 HIS A CB 1 ATOM 151 C CG . HIS A 1 25 ? 15.057 155.081 -0.678 1.00 10.61 ? 77 HIS A CG 1 ATOM 152 N ND1 . HIS A 1 25 ? 13.744 154.731 -0.446 1.00 12.77 ? 77 HIS A ND1 1 ATOM 153 C CD2 . HIS A 1 25 ? 15.348 156.059 0.211 1.00 12.01 ? 77 HIS A CD2 1 ATOM 154 C CE1 . HIS A 1 25 ? 13.257 155.475 0.528 1.00 11.12 ? 77 HIS A CE1 1 ATOM 155 N NE2 . HIS A 1 25 ? 14.211 156.287 0.948 1.00 11.78 ? 77 HIS A NE2 1 ATOM 156 N N . VAL A 1 26 ? 14.665 156.140 -4.734 1.00 12.84 ? 78 VAL A N 1 ATOM 157 C CA . VAL A 1 26 ? 14.836 157.311 -5.564 1.00 11.99 ? 78 VAL A CA 1 ATOM 158 C C . VAL A 1 26 ? 13.785 158.371 -5.273 1.00 12.76 ? 78 VAL A C 1 ATOM 159 O O . VAL A 1 26 ? 12.826 158.146 -4.532 1.00 13.02 ? 78 VAL A O 1 ATOM 160 C CB . VAL A 1 26 ? 14.778 156.942 -7.059 1.00 13.36 ? 78 VAL A CB 1 ATOM 161 C CG1 . VAL A 1 26 ? 15.825 155.897 -7.389 1.00 15.56 ? 78 VAL A CG1 1 ATOM 162 C CG2 . VAL A 1 26 ? 13.401 156.430 -7.450 1.00 14.37 ? 78 VAL A CG2 1 ATOM 163 N N . ASP A 1 27 ? 13.998 159.534 -5.871 1.00 13.37 ? 79 ASP A N 1 ATOM 164 C CA . ASP A 1 27 ? 13.049 160.629 -5.831 1.00 12.24 ? 79 ASP A CA 1 ATOM 165 C C . ASP A 1 27 ? 12.310 160.630 -7.149 1.00 16.01 ? 79 ASP A C 1 ATOM 166 O O . ASP A 1 27 ? 12.865 161.042 -8.163 1.00 18.45 ? 79 ASP A O 1 ATOM 167 C CB . ASP A 1 27 ? 13.769 161.964 -5.621 1.00 14.30 ? 79 ASP A CB 1 ATOM 168 C CG . ASP A 1 27 ? 12.814 163.144 -5.546 1.00 17.36 ? 79 ASP A CG 1 ATOM 169 O OD1 . ASP A 1 27 ? 11.790 163.046 -4.839 1.00 16.25 ? 79 ASP A OD1 1 ATOM 170 O OD2 . ASP A 1 27 ? 13.100 164.179 -6.184 1.00 18.28 ? 79 ASP A OD2 1 ATOM 171 N N . LEU A 1 28 ? 11.084 160.126 -7.158 1.00 15.22 ? 80 LEU A N 1 ATOM 172 C CA . LEU A 1 28 ? 10.318 160.114 -8.390 1.00 18.28 ? 80 LEU A CA 1 ATOM 173 C C . LEU A 1 28 ? 9.139 161.057 -8.306 1.00 14.46 ? 80 LEU A C 1 ATOM 174 O O . LEU A 1 28 ? 8.671 161.422 -7.220 1.00 15.47 ? 80 LEU A O 1 ATOM 175 C CB . LEU A 1 28 ? 9.845 158.699 -8.732 1.00 18.84 ? 80 LEU A CB 1 ATOM 176 C CG . LEU A 1 28 ? 8.761 158.012 -7.897 1.00 17.84 ? 80 LEU A CG 1 ATOM 177 C CD1 . LEU A 1 28 ? 7.343 158.445 -8.270 1.00 15.66 ? 80 LEU A CD1 1 ATOM 178 C CD2 . LEU A 1 28 ? 8.879 156.500 -8.054 1.00 18.19 ? 80 LEU A CD2 1 ATOM 179 N N . ILE A 1 29 ? 8.690 161.480 -9.479 1.00 15.43 ? 81 ILE A N 1 ATOM 180 C CA . ILE A 1 29 ? 7.464 162.237 -9.608 1.00 15.46 ? 81 ILE A CA 1 ATOM 181 C C . ILE A 1 29 ? 6.613 161.554 -10.676 1.00 16.34 ? 81 ILE A C 1 ATOM 182 O O . ILE A 1 29 ? 7.149 160.915 -11.587 1.00 16.43 ? 81 ILE A O 1 ATOM 183 C CB . ILE A 1 29 ? 7.733 163.702 -9.979 1.00 18.84 ? 81 ILE A CB 1 ATOM 184 C CG1 . ILE A 1 29 ? 8.656 163.770 -11.189 1.00 24.91 ? 81 ILE A CG1 1 ATOM 185 C CG2 . ILE A 1 29 ? 8.361 164.444 -8.798 1.00 18.37 ? 81 ILE A CG2 1 ATOM 186 C CD1 . ILE A 1 29 ? 8.501 165.007 -11.974 1.00 35.77 ? 81 ILE A CD1 1 ATOM 187 N N . TRP A 1 30 ? 5.296 161.674 -10.561 1.00 14.55 ? 82 TRP A N 1 ATOM 188 C CA . TRP A 1 30 ? 4.389 161.014 -11.502 1.00 14.79 ? 82 TRP A CA 1 ATOM 189 C C . TRP A 1 30 ? 4.265 161.863 -12.762 1.00 17.82 ? 82 TRP A C 1 ATOM 190 O O . TRP A 1 30 ? 4.102 163.078 -12.686 1.00 16.80 ? 82 TRP A O 1 ATOM 191 C CB . TRP A 1 30 ? 3.008 160.772 -10.865 1.00 13.68 ? 82 TRP A CB 1 ATOM 192 C CG . TRP A 1 30 ? 3.088 160.040 -9.562 1.00 12.67 ? 82 TRP A CG 1 ATOM 193 C CD1 . TRP A 1 30 ? 2.822 160.547 -8.320 1.00 14.47 ? 82 TRP A CD1 1 ATOM 194 C CD2 . TRP A 1 30 ? 3.496 158.685 -9.361 1.00 12.66 ? 82 TRP A CD2 1 ATOM 195 N NE1 . TRP A 1 30 ? 3.033 159.589 -7.363 1.00 13.34 ? 82 TRP A NE1 1 ATOM 196 C CE2 . TRP A 1 30 ? 3.439 158.433 -7.974 1.00 14.67 ? 82 TRP A CE2 1 ATOM 197 C CE3 . TRP A 1 30 ? 3.899 157.654 -10.218 1.00 13.68 ? 82 TRP A CE3 1 ATOM 198 C CZ2 . TRP A 1 30 ? 3.781 157.203 -7.423 1.00 15.46 ? 82 TRP A CZ2 1 ATOM 199 C CZ3 . TRP A 1 30 ? 4.235 156.427 -9.666 1.00 14.87 ? 82 TRP A CZ3 1 ATOM 200 C CH2 . TRP A 1 30 ? 4.169 156.212 -8.282 1.00 15.29 ? 82 TRP A CH2 1 ATOM 201 N N . ASP A 1 31 ? 4.372 161.220 -13.919 1.00 18.86 ? 83 ASP A N 1 ATOM 202 C CA . ASP A 1 31 ? 4.164 161.907 -15.189 1.00 23.32 ? 83 ASP A CA 1 ATOM 203 C C . ASP A 1 31 ? 3.916 160.893 -16.297 1.00 22.03 ? 83 ASP A C 1 ATOM 204 O O . ASP A 1 31 ? 4.655 159.921 -16.421 1.00 22.58 ? 83 ASP A O 1 ATOM 205 C CB . ASP A 1 31 ? 5.363 162.782 -15.537 1.00 28.12 ? 83 ASP A CB 1 ATOM 206 C CG . ASP A 1 31 ? 5.043 163.788 -16.626 1.00 35.01 ? 83 ASP A CG 1 ATOM 207 O OD1 . ASP A 1 31 ? 5.047 163.394 -17.809 1.00 31.85 ? 83 ASP A OD1 1 ATOM 208 O OD2 . ASP A 1 31 ? 4.767 164.966 -16.300 1.00 32.97 ? 83 ASP A OD2 1 ATOM 209 N N . LYS A 1 32 ? 2.888 161.117 -17.107 1.00 24.64 ? 84 LYS A N 1 ATOM 210 C CA . LYS A 1 32 ? 2.540 160.134 -18.131 1.00 23.98 ? 84 LYS A CA 1 ATOM 211 C C . LYS A 1 32 ? 3.590 160.076 -19.247 1.00 27.00 ? 84 LYS A C 1 ATOM 212 O O . LYS A 1 32 ? 3.593 159.137 -20.039 1.00 30.71 ? 84 LYS A O 1 ATOM 213 C CB . LYS A 1 32 ? 1.149 160.420 -18.709 1.00 29.57 ? 84 LYS A CB 1 ATOM 214 C CG . LYS A 1 32 ? 0.988 161.748 -19.410 1.00 34.03 ? 84 LYS A CG 1 ATOM 215 C CD . LYS A 1 32 ? -0.453 161.926 -19.865 1.00 40.73 ? 84 LYS A CD 1 ATOM 216 C CE . LYS A 1 32 ? -0.715 163.336 -20.350 1.00 45.02 ? 84 LYS A CE 1 ATOM 217 N NZ . LYS A 1 32 ? 0.221 163.732 -21.436 1.00 50.13 ? 84 LYS A NZ 1 ATOM 218 N N . ASP A 1 33 ? 4.493 161.054 -19.289 1.00 24.66 ? 85 ASP A N 1 ATOM 219 C CA . ASP A 1 33 ? 5.599 161.052 -20.251 1.00 28.84 ? 85 ASP A CA 1 ATOM 220 C C . ASP A 1 33 ? 6.926 160.638 -19.610 1.00 29.22 ? 85 ASP A C 1 ATOM 221 O O . ASP A 1 33 ? 7.981 160.710 -20.243 1.00 28.90 ? 85 ASP A O 1 ATOM 222 C CB . ASP A 1 33 ? 5.752 162.432 -20.892 1.00 30.24 ? 85 ASP A CB 1 ATOM 223 C CG . ASP A 1 33 ? 4.579 162.797 -21.784 1.00 35.48 ? 85 ASP A CG 1 ATOM 224 O OD1 . ASP A 1 33 ? 3.954 161.882 -22.361 1.00 43.11 ? 85 ASP A OD1 1 ATOM 225 O OD2 . ASP A 1 33 ? 4.284 164.003 -21.909 1.00 38.27 ? 85 ASP A OD2 1 ATOM 226 N N . GLY A 1 34 ? 6.881 160.208 -18.353 1.00 28.64 ? 86 GLY A N 1 ATOM 227 C CA . GLY A 1 34 ? 8.080 159.731 -17.688 1.00 24.34 ? 86 GLY A CA 1 ATOM 228 C C . GLY A 1 34 ? 8.626 158.491 -18.375 1.00 24.08 ? 86 GLY A C 1 ATOM 229 O O . GLY A 1 34 ? 7.865 157.701 -18.926 1.00 26.11 ? 86 GLY A O 1 ATOM 230 N N . THR A 1 35 ? 9.941 158.310 -18.335 1.00 24.28 ? 87 THR A N 1 ATOM 231 C CA . THR A 1 35 ? 10.574 157.196 -19.038 1.00 24.62 ? 87 THR A CA 1 ATOM 232 C C . THR A 1 35 ? 10.558 155.891 -18.239 1.00 25.75 ? 87 THR A C 1 ATOM 233 O O . THR A 1 35 ? 10.833 154.824 -18.785 1.00 28.40 ? 87 THR A O 1 ATOM 234 C CB . THR A 1 35 ? 12.026 157.535 -19.402 1.00 29.17 ? 87 THR A CB 1 ATOM 235 O OG1 . THR A 1 35 ? 12.771 157.806 -18.209 1.00 28.90 ? 87 THR A OG1 1 ATOM 236 C CG2 . THR A 1 35 ? 12.071 158.758 -20.326 1.00 34.11 ? 87 THR A CG2 1 ATOM 237 N N . LYS A 1 36 ? 10.224 155.972 -16.953 1.00 21.17 ? 88 LYS A N 1 ATOM 238 C CA . LYS A 1 36 ? 10.134 154.790 -16.100 1.00 19.78 ? 88 LYS A CA 1 ATOM 239 C C . LYS A 1 36 ? 8.706 154.265 -16.069 1.00 19.85 ? 88 LYS A C 1 ATOM 240 O O . LYS A 1 36 ? 7.759 155.047 -16.052 1.00 18.37 ? 88 LYS A O 1 ATOM 241 C CB . LYS A 1 36 ? 10.590 155.109 -14.674 1.00 18.53 ? 88 LYS A CB 1 ATOM 242 C CG . LYS A 1 36 ? 11.948 155.781 -14.585 1.00 19.47 ? 88 LYS A CG 1 ATOM 243 C CD . LYS A 1 36 ? 13.053 154.909 -15.154 1.00 22.74 ? 88 LYS A CD 1 ATOM 244 C CE . LYS A 1 36 ? 14.387 155.626 -15.082 1.00 25.69 ? 88 LYS A CE 1 ATOM 245 N NZ . LYS A 1 36 ? 15.496 154.815 -15.639 1.00 27.12 ? 88 LYS A NZ 1 ATOM 246 N N . SER A 1 37 ? 8.545 152.946 -16.047 1.00 20.82 ? 89 SER A N 1 ATOM 247 C CA . SER A 1 37 ? 7.206 152.377 -16.011 1.00 19.68 ? 89 SER A CA 1 ATOM 248 C C . SER A 1 37 ? 7.154 151.014 -15.359 1.00 18.32 ? 89 SER A C 1 ATOM 249 O O . SER A 1 37 ? 8.150 150.295 -15.288 1.00 22.83 ? 89 SER A O 1 ATOM 250 C CB . SER A 1 37 ? 6.629 152.281 -17.423 1.00 28.39 ? 89 SER A CB 1 ATOM 251 O OG . SER A 1 37 ? 7.362 151.375 -18.222 1.00 30.36 ? 89 SER A OG 1 ATOM 252 N N . HIS A 1 38 ? 5.972 150.679 -14.865 1.00 19.40 ? 90 HIS A N 1 ATOM 253 C CA . HIS A 1 38 ? 5.730 149.383 -14.272 1.00 19.07 ? 90 HIS A CA 1 ATOM 254 C C . HIS A 1 38 ? 4.253 149.086 -14.278 1.00 21.21 ? 90 HIS A C 1 ATOM 255 O O . HIS A 1 38 ? 3.448 149.941 -13.921 1.00 20.03 ? 90 HIS A O 1 ATOM 256 C CB . HIS A 1 38 ? 6.243 149.329 -12.842 1.00 20.07 ? 90 HIS A CB 1 ATOM 257 C CG . HIS A 1 38 ? 5.993 148.019 -12.166 1.00 15.96 ? 90 HIS A CG 1 ATOM 258 N ND1 . HIS A 1 38 ? 6.710 146.882 -12.469 1.00 19.44 ? 90 HIS A ND1 1 ATOM 259 C CD2 . HIS A 1 38 ? 5.118 147.667 -11.197 1.00 17.55 ? 90 HIS A CD2 1 ATOM 260 C CE1 . HIS A 1 38 ? 6.285 145.885 -11.715 1.00 20.17 ? 90 HIS A CE1 1 ATOM 261 N NE2 . HIS A 1 38 ? 5.319 146.335 -10.934 1.00 19.04 ? 90 HIS A NE2 1 ATOM 262 N N . THR A 1 39 ? 3.896 147.869 -14.671 1.00 22.50 ? 91 THR A N 1 ATOM 263 C CA . THR A 1 39 ? 2.507 147.463 -14.634 1.00 22.31 ? 91 THR A CA 1 ATOM 264 C C . THR A 1 39 ? 2.267 146.632 -13.381 1.00 22.73 ? 91 THR A C 1 ATOM 265 O O . THR A 1 39 ? 2.875 145.580 -13.187 1.00 27.89 ? 91 THR A O 1 ATOM 266 C CB . THR A 1 39 ? 2.119 146.691 -15.899 1.00 22.71 ? 91 THR A CB 1 ATOM 267 O OG1 . THR A 1 39 ? 2.368 147.525 -17.038 1.00 24.24 ? 91 THR A OG1 1 ATOM 268 C CG2 . THR A 1 39 ? 0.641 146.315 -15.868 1.00 28.99 ? 91 THR A CG2 1 ATOM 269 N N . ARG A 1 40 ? 1.402 147.151 -12.516 1.00 25.60 ? 92 ARG A N 1 ATOM 270 C CA . ARG A 1 40 ? 1.040 146.498 -11.267 1.00 27.01 ? 92 ARG A CA 1 ATOM 271 C C . ARG A 1 40 ? -0.446 146.208 -11.333 1.00 36.48 ? 92 ARG A C 1 ATOM 272 O O . ARG A 1 40 ? -1.270 147.126 -11.326 1.00 31.56 ? 92 ARG A O 1 ATOM 273 C CB . ARG A 1 40 ? 1.393 147.388 -10.066 1.00 30.48 ? 92 ARG A CB 1 ATOM 274 C CG . ARG A 1 40 ? 1.028 146.827 -8.699 1.00 29.87 ? 92 ARG A CG 1 ATOM 275 C CD . ARG A 1 40 ? 1.109 147.919 -7.632 1.00 31.98 ? 92 ARG A CD 1 ATOM 276 N NE . ARG A 1 40 ? 0.901 147.399 -6.281 1.00 27.34 ? 92 ARG A NE 1 ATOM 277 C CZ . ARG A 1 40 ? 1.871 146.976 -5.473 1.00 31.82 ? 92 ARG A CZ 1 ATOM 278 N NH1 . ARG A 1 40 ? 3.136 147.007 -5.866 1.00 28.57 ? 92 ARG A NH1 1 ATOM 279 N NH2 . ARG A 1 40 ? 1.575 146.519 -4.262 1.00 34.25 ? 92 ARG A NH2 1 ATOM 280 N N . GLY A 1 41 ? -0.787 144.927 -11.427 1.00 41.82 ? 93 GLY A N 1 ATOM 281 C CA . GLY A 1 41 ? -2.158 144.531 -11.679 1.00 43.65 ? 93 GLY A CA 1 ATOM 282 C C . GLY A 1 41 ? -2.567 144.909 -13.092 1.00 41.04 ? 93 GLY A C 1 ATOM 283 O O . GLY A 1 41 ? -1.976 144.439 -14.065 1.00 43.51 ? 93 GLY A O 1 ATOM 284 N N . ASN A 1 42 ? -3.567 145.781 -13.193 1.00 43.81 ? 94 ASN A N 1 ATOM 285 C CA . ASN A 1 42 ? -4.144 146.191 -14.476 1.00 49.18 ? 94 ASN A CA 1 ATOM 286 C C . ASN A 1 42 ? -3.666 147.568 -14.923 1.00 45.31 ? 94 ASN A C 1 ATOM 287 O O . ASN A 1 42 ? -4.035 148.047 -15.997 1.00 43.10 ? 94 ASN A O 1 ATOM 288 C CB . ASN A 1 42 ? -5.674 146.199 -14.384 1.00 53.46 ? 94 ASN A CB 1 ATOM 289 C CG . ASN A 1 42 ? -6.175 146.771 -13.068 1.00 62.56 ? 94 ASN A CG 1 ATOM 290 O OD1 . ASN A 1 42 ? -5.383 147.193 -12.223 1.00 61.07 ? 94 ASN A OD1 1 ATOM 291 N ND2 . ASN A 1 42 ? -7.493 146.789 -12.888 1.00 65.24 ? 94 ASN A ND2 1 ATOM 292 N N . THR A 1 43 ? -2.836 148.194 -14.095 1.00 37.19 ? 95 THR A N 1 ATOM 293 C CA . THR A 1 43 ? -2.466 149.592 -14.273 1.00 31.46 ? 95 THR A CA 1 ATOM 294 C C . THR A 1 43 ? -0.987 149.748 -14.583 1.00 25.26 ? 95 THR A C 1 ATOM 295 O O . THR A 1 43 ? -0.146 149.175 -13.896 1.00 26.10 ? 95 THR A O 1 ATOM 296 C CB . THR A 1 43 ? -2.800 150.400 -13.010 1.00 31.68 ? 95 THR A CB 1 ATOM 297 O OG1 . THR A 1 43 ? -4.189 150.234 -12.698 1.00 40.63 ? 95 THR A OG1 1 ATOM 298 C CG2 . THR A 1 43 ? -2.484 151.880 -13.199 1.00 25.91 ? 95 THR A CG2 1 ATOM 299 N N . THR A 1 44 ? -0.682 150.525 -15.616 1.00 23.43 ? 96 THR A N 1 ATOM 300 C CA . THR A 1 44 ? 0.697 150.875 -15.923 1.00 23.66 ? 96 THR A CA 1 ATOM 301 C C . THR A 1 44 ? 0.997 152.256 -15.365 1.00 21.14 ? 96 THR A C 1 ATOM 302 O O . THR A 1 44 ? 0.413 153.258 -15.785 1.00 23.87 ? 96 THR A O 1 ATOM 303 C CB . THR A 1 44 ? 0.977 150.852 -17.433 1.00 25.95 ? 96 THR A CB 1 ATOM 304 O OG1 . THR A 1 44 ? 0.755 149.525 -17.928 1.00 27.18 ? 96 THR A OG1 1 ATOM 305 C CG2 . THR A 1 44 ? 2.419 151.263 -17.726 1.00 27.03 ? 96 THR A CG2 1 ATOM 306 N N . TYR A 1 45 ? 1.909 152.287 -14.402 1.00 18.29 ? 97 TYR A N 1 ATOM 307 C CA . TYR A 1 45 ? 2.346 153.530 -13.781 1.00 19.07 ? 97 TYR A CA 1 ATOM 308 C C . TYR A 1 45 ? 3.535 154.102 -14.527 1.00 17.80 ? 97 TYR A C 1 ATOM 309 O O . TYR A 1 45 ? 4.413 153.357 -14.950 1.00 18.13 ? 97 TYR A O 1 ATOM 310 C CB . TYR A 1 45 ? 2.710 153.283 -12.321 1.00 16.33 ? 97 TYR A CB 1 ATOM 311 C CG . TYR A 1 45 ? 1.549 152.793 -11.498 1.00 15.33 ? 97 TYR A CG 1 ATOM 312 C CD1 . TYR A 1 45 ? 1.236 151.442 -11.433 1.00 19.27 ? 97 TYR A CD1 1 ATOM 313 C CD2 . TYR A 1 45 ? 0.752 153.685 -10.794 1.00 18.12 ? 97 TYR A CD2 1 ATOM 314 C CE1 . TYR A 1 45 ? 0.166 150.999 -10.687 1.00 18.83 ? 97 TYR A CE1 1 ATOM 315 C CE2 . TYR A 1 45 ? -0.316 153.250 -10.047 1.00 18.36 ? 97 TYR A CE2 1 ATOM 316 C CZ . TYR A 1 45 ? -0.605 151.908 -9.994 1.00 20.29 ? 97 TYR A CZ 1 ATOM 317 O OH . TYR A 1 45 ? -1.673 151.463 -9.252 1.00 25.13 ? 97 TYR A OH 1 ATOM 318 N N . ARG A 1 46 ? 3.557 155.420 -14.679 1.00 16.59 ? 98 ARG A N 1 ATOM 319 C CA . ARG A 1 46 ? 4.638 156.109 -15.371 1.00 18.04 ? 98 ARG A CA 1 ATOM 320 C C . ARG A 1 46 ? 5.246 157.181 -14.478 1.00 16.89 ? 98 ARG A C 1 ATOM 321 O O . ARG A 1 46 ? 4.524 157.952 -13.852 1.00 17.07 ? 98 ARG A O 1 ATOM 322 C CB . ARG A 1 46 ? 4.124 156.746 -16.662 1.00 23.58 ? 98 ARG A CB 1 ATOM 323 C CG . ARG A 1 46 ? 3.436 155.769 -17.600 1.00 28.66 ? 98 ARG A CG 1 ATOM 324 C CD . ARG A 1 46 ? 4.448 155.075 -18.464 1.00 36.33 ? 98 ARG A CD 1 ATOM 325 N NE . ARG A 1 46 ? 4.861 155.934 -19.570 1.00 44.39 ? 98 ARG A NE 1 ATOM 326 C CZ . ARG A 1 46 ? 6.044 155.880 -20.176 1.00 48.79 ? 98 ARG A CZ 1 ATOM 327 N NH1 . ARG A 1 46 ? 6.311 156.715 -21.172 1.00 48.02 ? 98 ARG A NH1 1 ATOM 328 N NH2 . ARG A 1 46 ? 6.968 155.012 -19.781 1.00 47.22 ? 98 ARG A NH2 1 ATOM 329 N N . TRP A 1 47 ? 6.569 157.246 -14.435 1.00 16.06 ? 99 TRP A N 1 ATOM 330 C CA . TRP A 1 47 ? 7.222 158.255 -13.615 1.00 14.44 ? 99 TRP A CA 1 ATOM 331 C C . TRP A 1 47 ? 8.584 158.687 -14.139 1.00 17.20 ? 99 TRP A C 1 ATOM 332 O O . TRP A 1 47 ? 9.172 158.067 -15.031 1.00 18.51 ? 99 TRP A O 1 ATOM 333 C CB . TRP A 1 47 ? 7.348 157.747 -12.171 1.00 15.07 ? 99 TRP A CB 1 ATOM 334 C CG . TRP A 1 47 ? 8.313 156.596 -11.925 1.00 14.16 ? 99 TRP A CG 1 ATOM 335 C CD1 . TRP A 1 47 ? 9.643 156.687 -11.596 1.00 15.91 ? 99 TRP A CD1 1 ATOM 336 C CD2 . TRP A 1 47 ? 8.010 155.193 -11.953 1.00 13.28 ? 99 TRP A CD2 1 ATOM 337 N NE1 . TRP A 1 47 ? 10.175 155.431 -11.417 1.00 15.12 ? 99 TRP A NE1 1 ATOM 338 C CE2 . TRP A 1 47 ? 9.194 154.500 -11.630 1.00 16.38 ? 99 TRP A CE2 1 ATOM 339 C CE3 . TRP A 1 47 ? 6.848 154.457 -12.209 1.00 16.32 ? 99 TRP A CE3 1 ATOM 340 C CZ2 . TRP A 1 47 ? 9.254 153.110 -11.574 1.00 14.93 ? 99 TRP A CZ2 1 ATOM 341 C CZ3 . TRP A 1 47 ? 6.910 153.071 -12.149 1.00 17.17 ? 99 TRP A CZ3 1 ATOM 342 C CH2 . TRP A 1 47 ? 8.105 152.413 -11.836 1.00 16.52 ? 99 TRP A CH2 1 ATOM 343 N N . THR A 1 48 ? 9.050 159.802 -13.587 1.00 16.93 ? 100 THR A N 1 ATOM 344 C CA . THR A 1 48 ? 10.390 160.310 -13.813 1.00 18.50 ? 100 THR A CA 1 ATOM 345 C C . THR A 1 48 ? 11.191 160.181 -12.532 1.00 18.52 ? 100 THR A C 1 ATOM 346 O O . THR A 1 48 ? 10.706 160.506 -11.452 1.00 18.76 ? 100 THR A O 1 ATOM 347 C CB . THR A 1 48 ? 10.365 161.788 -14.258 1.00 21.57 ? 100 THR A CB 1 ATOM 348 O OG1 . THR A 1 48 ? 9.869 161.876 -15.598 1.00 24.33 ? 100 THR A OG1 1 ATOM 349 C CG2 . THR A 1 48 ? 11.760 162.414 -14.194 1.00 24.70 ? 100 THR A CG2 1 ATOM 350 N N . GLU A 1 49 ? 12.427 159.728 -12.662 1.00 18.13 ? 101 GLU A N 1 ATOM 351 C CA . GLU A 1 49 ? 13.342 159.653 -11.538 1.00 16.08 ? 101 GLU A CA 1 ATOM 352 C C . GLU A 1 49 ? 14.227 160.893 -11.546 1.00 17.65 ? 101 GLU A C 1 ATOM 353 O O . GLU A 1 49 ? 15.046 161.067 -12.444 1.00 20.33 ? 101 GLU A O 1 ATOM 354 C CB . GLU A 1 49 ? 14.167 158.377 -11.633 1.00 20.22 ? 101 GLU A CB 1 ATOM 355 C CG . GLU A 1 49 ? 15.197 158.191 -10.568 1.00 25.35 ? 101 GLU A CG 1 ATOM 356 C CD . GLU A 1 49 ? 15.994 156.918 -10.779 1.00 28.30 ? 101 GLU A CD 1 ATOM 357 O OE1 . GLU A 1 49 ? 15.361 155.850 -10.995 1.00 22.00 ? 101 GLU A OE1 1 ATOM 358 O OE2 . GLU A 1 49 ? 17.249 156.991 -10.747 1.00 22.20 ? 101 GLU A OE2 1 ATOM 359 N N . ARG A 1 50 ? 14.044 161.758 -10.553 1.00 15.54 ? 102 ARG A N 1 ATOM 360 C CA . ARG A 1 50 ? 14.769 163.028 -10.489 1.00 15.60 ? 102 ARG A CA 1 ATOM 361 C C . ARG A 1 50 ? 16.180 162.838 -9.952 1.00 17.53 ? 102 ARG A C 1 ATOM 362 O O . ARG A 1 50 ? 17.131 163.473 -10.418 1.00 16.27 ? 102 ARG A O 1 ATOM 363 C CB . ARG A 1 50 ? 14.011 164.033 -9.617 1.00 16.56 ? 102 ARG A CB 1 ATOM 364 C CG . ARG A 1 50 ? 12.633 164.345 -10.152 1.00 15.74 ? 102 ARG A CG 1 ATOM 365 C CD . ARG A 1 50 ? 12.135 165.709 -9.697 1.00 15.24 ? 102 ARG A CD 1 ATOM 366 N NE . ARG A 1 50 ? 11.998 165.803 -8.243 1.00 15.17 ? 102 ARG A NE 1 ATOM 367 C CZ . ARG A 1 50 ? 11.551 166.881 -7.610 1.00 14.33 ? 102 ARG A CZ 1 ATOM 368 N NH1 . ARG A 1 50 ? 11.467 166.885 -6.284 1.00 15.34 ? 102 ARG A NH1 1 ATOM 369 N NH2 . ARG A 1 50 ? 11.188 167.951 -8.307 1.00 16.89 ? 102 ARG A NH2 1 ATOM 370 N N . LYS A 1 51 ? 16.312 161.959 -8.968 1.00 14.47 ? 103 LYS A N 1 ATOM 371 C CA . LYS A 1 51 ? 17.617 161.636 -8.415 1.00 16.13 ? 103 LYS A CA 1 ATOM 372 C C . LYS A 1 51 ? 17.554 160.312 -7.679 1.00 15.10 ? 103 LYS A C 1 ATOM 373 O O . LYS A 1 51 ? 16.479 159.843 -7.314 1.00 14.86 ? 103 LYS A O 1 ATOM 374 C CB . LYS A 1 51 ? 18.113 162.743 -7.472 1.00 22.13 ? 103 LYS A CB 1 ATOM 375 C CG . LYS A 1 51 ? 17.439 162.792 -6.102 1.00 20.35 ? 103 LYS A CG 1 ATOM 376 C CD . LYS A 1 51 ? 18.040 163.869 -5.181 1.00 22.91 ? 103 LYS A CD 1 ATOM 377 C CE . LYS A 1 51 ? 19.537 163.665 -4.876 1.00 27.30 ? 103 LYS A CE 1 ATOM 378 N NZ . LYS A 1 51 ? 19.821 162.582 -3.878 1.00 28.76 ? 103 LYS A NZ 1 ATOM 379 N N . SER A 1 52 ? 18.713 159.710 -7.460 1.00 14.68 ? 104 SER A N 1 ATOM 380 C CA . SER A 1 52 ? 18.794 158.492 -6.669 1.00 13.81 ? 104 SER A CA 1 ATOM 381 C C . SER A 1 52 ? 19.328 158.815 -5.276 1.00 14.74 ? 104 SER A C 1 ATOM 382 O O . SER A 1 52 ? 19.569 159.984 -4.948 1.00 15.53 ? 104 SER A O 1 ATOM 383 C CB . SER A 1 52 ? 19.680 157.471 -7.374 1.00 17.92 ? 104 SER A CB 1 ATOM 384 O OG . SER A 1 52 ? 21.019 157.921 -7.432 1.00 21.26 ? 104 SER A OG 1 ATOM 385 N N . ASN A 1 53 ? 19.484 157.783 -4.452 1.00 13.51 ? 105 ASN A N 1 ATOM 386 C CA . ASN A 1 53 ? 20.130 157.926 -3.152 1.00 12.51 ? 105 ASN A CA 1 ATOM 387 C C . ASN A 1 53 ? 19.449 158.953 -2.245 1.00 13.17 ? 105 ASN A C 1 ATOM 388 O O . ASN A 1 53 ? 20.115 159.762 -1.587 1.00 14.12 ? 105 ASN A O 1 ATOM 389 C CB . ASN A 1 53 ? 21.599 158.303 -3.349 1.00 15.09 ? 105 ASN A CB 1 ATOM 390 C CG . ASN A 1 53 ? 22.434 158.098 -2.095 1.00 19.69 ? 105 ASN A CG 1 ATOM 391 O OD1 . ASN A 1 53 ? 22.214 157.157 -1.333 1.00 16.57 ? 105 ASN A OD1 1 ATOM 392 N ND2 . ASN A 1 53 ? 23.400 158.990 -1.872 1.00 23.94 ? 105 ASN A ND2 1 ATOM 393 N N . VAL A 1 54 ? 18.120 158.937 -2.227 1.00 12.27 ? 106 VAL A N 1 ATOM 394 C CA . VAL A 1 54 ? 17.361 159.769 -1.293 1.00 10.64 ? 106 VAL A CA 1 ATOM 395 C C . VAL A 1 54 ? 17.671 159.321 0.135 1.00 10.99 ? 106 VAL A C 1 ATOM 396 O O . VAL A 1 54 ? 17.869 158.135 0.391 1.00 11.71 ? 106 VAL A O 1 ATOM 397 C CB . VAL A 1 54 ? 15.838 159.679 -1.573 1.00 12.99 ? 106 VAL A CB 1 ATOM 398 C CG1 . VAL A 1 54 ? 15.014 160.380 -0.484 1.00 11.07 ? 106 VAL A CG1 1 ATOM 399 C CG2 . VAL A 1 54 ? 15.524 160.281 -2.932 1.00 12.72 ? 106 VAL A CG2 1 ATOM 400 N N . GLY A 1 55 ? 17.713 160.262 1.073 1.00 11.18 ? 107 GLY A N 1 ATOM 401 C CA . GLY A 1 55 ? 17.979 159.915 2.461 1.00 10.32 ? 107 GLY A CA 1 ATOM 402 C C . GLY A 1 55 ? 16.968 158.919 3.026 1.00 10.02 ? 107 GLY A C 1 ATOM 403 O O . GLY A 1 55 ? 15.764 159.076 2.834 1.00 12.65 ? 107 GLY A O 1 ATOM 404 N N . VAL A 1 56 ? 17.459 157.900 3.724 1.00 9.56 ? 108 VAL A N 1 ATOM 405 C CA . VAL A 1 56 ? 16.607 156.857 4.305 1.00 10.98 ? 108 VAL A CA 1 ATOM 406 C C . VAL A 1 56 ? 16.112 157.242 5.705 1.00 11.60 ? 108 VAL A C 1 ATOM 407 O O . VAL A 1 56 ? 14.929 157.106 6.023 1.00 11.10 ? 108 VAL A O 1 ATOM 408 C CB . VAL A 1 56 ? 17.368 155.501 4.357 1.00 10.88 ? 108 VAL A CB 1 ATOM 409 C CG1 . VAL A 1 56 ? 16.632 154.446 5.201 1.00 9.32 ? 108 VAL A CG1 1 ATOM 410 C CG2 . VAL A 1 56 ? 17.603 154.988 2.949 1.00 10.21 ? 108 VAL A CG2 1 ATOM 411 N N . TYR A 1 57 ? 17.014 157.725 6.550 1.00 10.63 ? 109 TYR A N 1 ATOM 412 C CA . TYR A 1 57 ? 16.634 158.173 7.877 1.00 9.80 ? 109 TYR A CA 1 ATOM 413 C C . TYR A 1 57 ? 15.687 159.360 7.753 1.00 9.52 ? 109 TYR A C 1 ATOM 414 O O . TYR A 1 57 ? 14.613 159.391 8.350 1.00 10.26 ? 109 TYR A O 1 ATOM 415 C CB . TYR A 1 57 ? 17.890 158.539 8.679 1.00 9.30 ? 109 TYR A CB 1 ATOM 416 C CG . TYR A 1 57 ? 17.674 158.812 10.147 1.00 9.96 ? 109 TYR A CG 1 ATOM 417 C CD1 . TYR A 1 57 ? 17.260 157.800 11.015 1.00 10.64 ? 109 TYR A CD1 1 ATOM 418 C CD2 . TYR A 1 57 ? 17.923 160.065 10.684 1.00 12.13 ? 109 TYR A CD2 1 ATOM 419 C CE1 . TYR A 1 57 ? 17.078 158.046 12.372 1.00 12.22 ? 109 TYR A CE1 1 ATOM 420 C CE2 . TYR A 1 57 ? 17.751 160.310 12.037 1.00 9.75 ? 109 TYR A CE2 1 ATOM 421 C CZ . TYR A 1 57 ? 17.340 159.301 12.873 1.00 11.72 ? 109 TYR A CZ 1 ATOM 422 O OH . TYR A 1 57 ? 17.169 159.565 14.218 1.00 15.16 ? 109 TYR A OH 1 ATOM 423 N N . VAL A 1 58 ? 16.124 160.341 6.970 1.00 9.28 ? 110 VAL A N 1 ATOM 424 C CA . VAL A 1 58 ? 15.349 161.525 6.636 1.00 10.58 ? 110 VAL A CA 1 ATOM 425 C C . VAL A 1 58 ? 15.454 161.736 5.126 1.00 10.54 ? 110 VAL A C 1 ATOM 426 O O . VAL A 1 58 ? 16.564 161.889 4.607 1.00 10.02 ? 110 VAL A O 1 ATOM 427 C CB . VAL A 1 58 ? 15.877 162.767 7.381 1.00 10.79 ? 110 VAL A CB 1 ATOM 428 C CG1 . VAL A 1 58 ? 15.208 164.036 6.858 1.00 11.89 ? 110 VAL A CG1 1 ATOM 429 C CG2 . VAL A 1 58 ? 15.649 162.607 8.861 1.00 11.83 ? 110 VAL A CG2 1 ATOM 430 N N . GLY A 1 59 ? 14.317 161.726 4.428 1.00 11.37 ? 111 GLY A N 1 ATOM 431 C CA . GLY A 1 59 ? 14.298 161.860 2.981 1.00 9.53 ? 111 GLY A CA 1 ATOM 432 C C . GLY A 1 59 ? 13.502 163.061 2.531 1.00 10.96 ? 111 GLY A C 1 ATOM 433 O O . GLY A 1 59 ? 12.343 163.208 2.903 1.00 10.25 ? 111 GLY A O 1 ATOM 434 N N . TYR A 1 60 ? 14.139 163.918 1.734 1.00 10.31 ? 112 TYR A N 1 ATOM 435 C CA . TYR A 1 60 ? 13.528 165.140 1.224 1.00 12.66 ? 112 TYR A CA 1 ATOM 436 C C . TYR A 1 60 ? 13.862 165.350 -0.241 1.00 11.43 ? 112 TYR A C 1 ATOM 437 O O . TYR A 1 60 ? 14.967 165.031 -0.694 1.00 13.31 ? 112 TYR A O 1 ATOM 438 C CB . TYR A 1 60 ? 14.023 166.388 1.976 1.00 11.10 ? 112 TYR A CB 1 ATOM 439 C CG . TYR A 1 60 ? 13.690 166.479 3.440 1.00 10.51 ? 112 TYR A CG 1 ATOM 440 C CD1 . TYR A 1 60 ? 12.402 166.276 3.904 1.00 9.59 ? 112 TYR A CD1 1 ATOM 441 C CD2 . TYR A 1 60 ? 14.672 166.785 4.361 1.00 11.74 ? 112 TYR A CD2 1 ATOM 442 C CE1 . TYR A 1 60 ? 12.104 166.359 5.254 1.00 11.72 ? 112 TYR A CE1 1 ATOM 443 C CE2 . TYR A 1 60 ? 14.388 166.878 5.715 1.00 12.58 ? 112 TYR A CE2 1 ATOM 444 C CZ . TYR A 1 60 ? 13.107 166.660 6.160 1.00 10.70 ? 112 TYR A CZ 1 ATOM 445 O OH . TYR A 1 60 ? 12.820 166.744 7.503 1.00 11.90 ? 112 TYR A OH 1 ATOM 446 N N . SER A 1 61 ? 12.924 165.952 -0.961 1.00 11.35 ? 113 SER A N 1 ATOM 447 C CA . SER A 1 61 ? 13.239 166.581 -2.234 1.00 12.32 ? 113 SER A CA 1 ATOM 448 C C . SER A 1 61 ? 12.405 167.844 -2.370 1.00 10.85 ? 113 SER A C 1 ATOM 449 O O . SER A 1 61 ? 11.458 168.061 -1.616 1.00 11.89 ? 113 SER A O 1 ATOM 450 C CB . SER A 1 61 ? 12.981 165.638 -3.401 1.00 15.33 ? 113 SER A CB 1 ATOM 451 O OG . SER A 1 61 ? 11.597 165.392 -3.545 1.00 15.52 ? 113 SER A OG 1 ATOM 452 N N . GLU A 1 62 ? 12.765 168.693 -3.321 1.00 13.87 ? 114 GLU A N 1 ATOM 453 C CA . GLU A 1 62 ? 12.037 169.932 -3.511 1.00 14.38 ? 114 GLU A CA 1 ATOM 454 C C . GLU A 1 62 ? 10.577 169.683 -3.846 1.00 13.69 ? 114 GLU A C 1 ATOM 455 O O . GLU A 1 62 ? 10.254 168.857 -4.698 1.00 14.35 ? 114 GLU A O 1 ATOM 456 C CB . GLU A 1 62 ? 12.681 170.760 -4.618 1.00 16.51 ? 114 GLU A CB 1 ATOM 457 C CG . GLU A 1 62 ? 13.995 171.427 -4.206 1.00 16.59 ? 114 GLU A CG 1 ATOM 458 C CD . GLU A 1 62 ? 15.174 170.473 -4.114 1.00 19.18 ? 114 GLU A CD 1 ATOM 459 O OE1 . GLU A 1 62 ? 15.082 169.327 -4.609 1.00 20.20 ? 114 GLU A OE1 1 ATOM 460 O OE2 . GLU A 1 62 ? 16.203 170.882 -3.534 1.00 21.60 ? 114 GLU A OE2 1 ATOM 461 N N . MET A 1 63 ? 9.701 170.404 -3.161 1.00 12.70 ? 115 MET A N 1 ATOM 462 C CA . MET A 1 63 ? 8.287 170.334 -3.454 1.00 13.16 ? 115 MET A CA 1 ATOM 463 C C . MET A 1 63 ? 8.068 170.479 -4.957 1.00 13.33 ? 115 MET A C 1 ATOM 464 O O . MET A 1 63 ? 8.576 171.405 -5.594 1.00 14.10 ? 115 MET A O 1 ATOM 465 C CB . MET A 1 63 ? 7.521 171.410 -2.686 1.00 15.39 ? 115 MET A CB 1 ATOM 466 C CG . MET A 1 63 ? 6.030 171.490 -3.037 1.00 15.23 ? 115 MET A CG 1 ATOM 467 S SD . MET A 1 63 ? 5.103 169.965 -2.755 1.00 15.56 ? 115 MET A SD 1 ATOM 468 C CE . MET A 1 63 ? 4.982 169.960 -0.962 1.00 15.43 ? 115 MET A CE 1 ATOM 469 N N . TYR A 1 64 ? 7.325 169.528 -5.509 1.00 13.79 ? 116 TYR A N 1 ATOM 470 C CA . TYR A 1 64 ? 7.020 169.484 -6.928 1.00 13.14 ? 116 TYR A CA 1 ATOM 471 C C . TYR A 1 64 ? 5.520 169.631 -7.085 1.00 14.99 ? 116 TYR A C 1 ATOM 472 O O . TYR A 1 64 ? 4.759 168.823 -6.548 1.00 14.44 ? 116 TYR A O 1 ATOM 473 C CB . TYR A 1 64 ? 7.498 168.168 -7.534 1.00 14.32 ? 116 TYR A CB 1 ATOM 474 C CG . TYR A 1 64 ? 7.162 167.979 -8.990 1.00 14.69 ? 116 TYR A CG 1 ATOM 475 C CD1 . TYR A 1 64 ? 7.942 168.562 -9.978 1.00 17.14 ? 116 TYR A CD1 1 ATOM 476 C CD2 . TYR A 1 64 ? 6.092 167.190 -9.377 1.00 16.79 ? 116 TYR A CD2 1 ATOM 477 C CE1 . TYR A 1 64 ? 7.652 168.379 -11.317 1.00 18.32 ? 116 TYR A CE1 1 ATOM 478 C CE2 . TYR A 1 64 ? 5.788 167.001 -10.717 1.00 18.07 ? 116 TYR A CE2 1 ATOM 479 C CZ . TYR A 1 64 ? 6.574 167.597 -11.677 1.00 16.91 ? 116 TYR A CZ 1 ATOM 480 O OH . TYR A 1 64 ? 6.280 167.405 -13.007 1.00 19.87 ? 116 TYR A OH 1 ATOM 481 N N . ASP A 1 65 ? 5.098 170.661 -7.808 1.00 15.02 ? 117 ASP A N 1 ATOM 482 C CA . ASP A 1 65 ? 3.682 170.903 -8.035 1.00 16.28 ? 117 ASP A CA 1 ATOM 483 C C . ASP A 1 65 ? 3.431 171.129 -9.523 1.00 17.32 ? 117 ASP A C 1 ATOM 484 O O . ASP A 1 65 ? 3.741 172.189 -10.065 1.00 16.83 ? 117 ASP A O 1 ATOM 485 C CB . ASP A 1 65 ? 3.196 172.096 -7.213 1.00 16.63 ? 117 ASP A CB 1 ATOM 486 C CG . ASP A 1 65 ? 1.685 172.173 -7.140 1.00 15.87 ? 117 ASP A CG 1 ATOM 487 O OD1 . ASP A 1 65 ? 1.030 171.741 -8.108 1.00 16.84 ? 117 ASP A OD1 1 ATOM 488 O OD2 . ASP A 1 65 ? 1.151 172.655 -6.119 1.00 14.59 ? 117 ASP A OD2 1 ATOM 489 N N . SER A 1 66 ? 2.856 170.122 -10.169 1.00 17.48 ? 118 SER A N 1 ATOM 490 C CA . SER A 1 66 ? 2.552 170.189 -11.593 1.00 16.93 ? 118 SER A CA 1 ATOM 491 C C . SER A 1 66 ? 1.054 170.382 -11.829 1.00 17.02 ? 118 SER A C 1 ATOM 492 O O . SER A 1 66 ? 0.541 170.053 -12.896 1.00 18.77 ? 118 SER A O 1 ATOM 493 C CB . SER A 1 66 ? 3.043 168.929 -12.305 1.00 19.75 ? 118 SER A CB 1 ATOM 494 O OG . SER A 1 66 ? 2.480 167.770 -11.725 1.00 20.08 ? 118 SER A OG 1 ATOM 495 N N . SER A 1 67 ? 0.351 170.913 -10.832 1.00 17.27 ? 119 SER A N 1 ATOM 496 C CA . SER A 1 67 ? -1.001 171.403 -11.074 1.00 16.78 ? 119 SER A CA 1 ATOM 497 C C . SER A 1 67 ? -0.866 172.601 -12.009 1.00 17.20 ? 119 SER A C 1 ATOM 498 O O . SER A 1 67 ? 0.212 173.183 -12.133 1.00 19.12 ? 119 SER A O 1 ATOM 499 C CB . SER A 1 67 ? -1.718 171.778 -9.764 1.00 16.55 ? 119 SER A CB 1 ATOM 500 O OG . SER A 1 67 ? -1.090 172.874 -9.117 1.00 16.60 ? 119 SER A OG 1 ATOM 501 N N . ALA A 1 68 ? -1.950 172.962 -12.682 1.00 16.87 ? 120 ALA A N 1 ATOM 502 C CA . ALA A 1 68 ? -1.916 174.077 -13.617 1.00 20.95 ? 120 ALA A CA 1 ATOM 503 C C . ALA A 1 68 ? -1.454 175.368 -12.934 1.00 22.21 ? 120 ALA A C 1 ATOM 504 O O . ALA A 1 68 ? -0.742 176.176 -13.537 1.00 21.69 ? 120 ALA A O 1 ATOM 505 C CB . ALA A 1 68 ? -3.278 174.265 -14.240 1.00 21.41 ? 120 ALA A CB 1 ATOM 506 N N . GLN A 1 69 ? -1.846 175.552 -11.673 1.00 19.38 ? 121 GLN A N 1 ATOM 507 C CA . GLN A 1 69 ? -1.479 176.756 -10.923 1.00 18.39 ? 121 GLN A CA 1 ATOM 508 C C . GLN A 1 69 ? -0.160 176.618 -10.158 1.00 19.80 ? 121 GLN A C 1 ATOM 509 O O . GLN A 1 69 ? 0.373 177.613 -9.665 1.00 19.60 ? 121 GLN A O 1 ATOM 510 C CB . GLN A 1 69 ? -2.592 177.131 -9.937 1.00 20.50 ? 121 GLN A CB 1 ATOM 511 C CG . GLN A 1 69 ? -3.938 177.397 -10.589 1.00 22.99 ? 121 GLN A CG 1 ATOM 512 C CD . GLN A 1 69 ? -3.838 178.366 -11.747 1.00 28.55 ? 121 GLN A CD 1 ATOM 513 O OE1 . GLN A 1 69 ? -3.203 179.414 -11.639 1.00 29.12 ? 121 GLN A OE1 1 ATOM 514 N NE2 . GLN A 1 69 ? -4.439 178.006 -12.874 1.00 27.63 ? 121 GLN A NE2 1 ATOM 515 N N . ALA A 1 70 ? 0.353 175.393 -10.055 1.00 17.96 ? 122 ALA A N 1 ATOM 516 C CA . ALA A 1 70 ? 1.610 175.126 -9.352 1.00 17.93 ? 122 ALA A CA 1 ATOM 517 C C . ALA A 1 70 ? 1.607 175.737 -7.949 1.00 17.00 ? 122 ALA A C 1 ATOM 518 O O . ALA A 1 70 ? 2.609 176.292 -7.503 1.00 17.47 ? 122 ALA A O 1 ATOM 519 C CB . ALA A 1 70 ? 2.797 175.653 -10.166 1.00 19.51 ? 122 ALA A CB 1 ATOM 520 N N . TYR A 1 71 ? 0.477 175.602 -7.256 1.00 17.02 ? 123 TYR A N 1 ATOM 521 C CA . TYR A 1 71 ? 0.241 176.275 -5.976 1.00 16.25 ? 123 TYR A CA 1 ATOM 522 C C . TYR A 1 71 ? 1.394 176.183 -4.985 1.00 16.86 ? 123 TYR A C 1 ATOM 523 O O . TYR A 1 71 ? 1.854 177.194 -4.467 1.00 17.58 ? 123 TYR A O 1 ATOM 524 C CB . TYR A 1 71 ? -0.999 175.697 -5.291 1.00 19.12 ? 123 TYR A CB 1 ATOM 525 C CG . TYR A 1 71 ? -2.292 175.836 -6.062 1.00 15.25 ? 123 TYR A CG 1 ATOM 526 C CD1 . TYR A 1 71 ? -2.931 177.065 -6.165 1.00 17.02 ? 123 TYR A CD1 1 ATOM 527 C CD2 . TYR A 1 71 ? -2.888 174.735 -6.656 1.00 17.40 ? 123 TYR A CD2 1 ATOM 528 C CE1 . TYR A 1 71 ? -4.123 177.191 -6.859 1.00 16.37 ? 123 TYR A CE1 1 ATOM 529 C CE2 . TYR A 1 71 ? -4.076 174.852 -7.349 1.00 18.00 ? 123 TYR A CE2 1 ATOM 530 C CZ . TYR A 1 71 ? -4.688 176.085 -7.445 1.00 17.94 ? 123 TYR A CZ 1 ATOM 531 O OH . TYR A 1 71 ? -5.876 176.203 -8.130 1.00 19.07 ? 123 TYR A OH 1 ATOM 532 N N . CYS A 1 72 ? 1.844 174.966 -4.705 1.00 15.77 ? 124 CYS A N 1 ATOM 533 C CA . CYS A 1 72 ? 2.760 174.757 -3.593 1.00 14.57 ? 124 CYS A CA 1 ATOM 534 C C . CYS A 1 72 ? 4.212 175.037 -3.966 1.00 18.50 ? 124 CYS A C 1 ATOM 535 O O . CYS A 1 72 ? 5.099 174.894 -3.128 1.00 18.70 ? 124 CYS A O 1 ATOM 536 C CB . CYS A 1 72 ? 2.621 173.330 -3.053 1.00 14.35 ? 124 CYS A CB 1 ATOM 537 S SG . CYS A 1 72 ? 0.967 172.951 -2.384 1.00 18.20 ? 124 CYS A SG 1 ATOM 538 N N . GLN A 1 73 ? 4.452 175.452 -5.208 1.00 16.25 ? 125 GLN A N 1 ATOM 539 C CA . GLN A 1 73 ? 5.781 175.913 -5.621 1.00 16.36 ? 125 GLN A CA 1 ATOM 540 C C . GLN A 1 73 ? 5.952 177.420 -5.426 1.00 18.49 ? 125 GLN A C 1 ATOM 541 O O . GLN A 1 73 ? 7.051 177.950 -5.581 1.00 21.72 ? 125 GLN A O 1 ATOM 542 C CB . GLN A 1 73 ? 6.053 175.544 -7.084 1.00 19.50 ? 125 GLN A CB 1 ATOM 543 C CG . GLN A 1 73 ? 6.428 174.086 -7.250 1.00 17.24 ? 125 GLN A CG 1 ATOM 544 C CD . GLN A 1 73 ? 6.728 173.659 -8.683 1.00 17.64 ? 125 GLN A CD 1 ATOM 545 O OE1 . GLN A 1 73 ? 6.968 172.481 -8.934 1.00 17.50 ? 125 GLN A OE1 1 ATOM 546 N NE2 . GLN A 1 73 ? 6.706 174.604 -9.629 1.00 18.49 ? 125 GLN A NE2 1 ATOM 547 N N . SER A 1 74 ? 4.866 178.100 -5.080 1.00 19.58 ? 126 SER A N 1 ATOM 548 C CA . SER A 1 74 ? 4.893 179.546 -4.843 1.00 22.35 ? 126 SER A CA 1 ATOM 549 C C . SER A 1 74 ? 5.743 179.918 -3.636 1.00 24.87 ? 126 SER A C 1 ATOM 550 O O . SER A 1 74 ? 5.762 179.199 -2.634 1.00 20.03 ? 126 SER A O 1 ATOM 551 C CB . SER A 1 74 ? 3.478 180.074 -4.633 1.00 21.86 ? 126 SER A CB 1 ATOM 552 O OG . SER A 1 74 ? 3.504 181.433 -4.218 1.00 22.60 ? 126 SER A OG 1 ATOM 553 N N . SER A 1 75 ? 6.422 181.059 -3.723 1.00 25.70 ? 127 SER A N 1 ATOM 554 C CA . SER A 1 75 ? 7.233 181.538 -2.611 1.00 25.44 ? 127 SER A CA 1 ATOM 555 C C . SER A 1 75 ? 6.358 181.910 -1.418 1.00 24.45 ? 127 SER A C 1 ATOM 556 O O . SER A 1 75 ? 6.847 181.975 -0.290 1.00 28.46 ? 127 SER A O 1 ATOM 557 C CB . SER A 1 75 ? 8.085 182.739 -3.036 1.00 31.89 ? 127 SER A CB 1 ATOM 558 O OG . SER A 1 75 ? 7.272 183.792 -3.522 1.00 31.32 ? 127 SER A OG 1 ATOM 559 N N . SER A 1 76 ? 5.068 182.139 -1.660 1.00 23.36 ? 128 SER A N 1 ATOM 560 C CA . SER A 1 76 ? 4.147 182.496 -0.584 1.00 23.02 ? 128 SER A CA 1 ATOM 561 C C . SER A 1 76 ? 3.424 181.275 -0.019 1.00 24.05 ? 128 SER A C 1 ATOM 562 O O . SER A 1 76 ? 2.616 181.400 0.898 1.00 24.89 ? 128 SER A O 1 ATOM 563 C CB . SER A 1 76 ? 3.126 183.525 -1.071 1.00 29.83 ? 128 SER A CB 1 ATOM 564 O OG . SER A 1 76 ? 2.321 182.995 -2.106 1.00 37.70 ? 128 SER A OG 1 ATOM 565 N N . ALA A 1 77 ? 3.704 180.098 -0.572 1.00 22.94 ? 129 ALA A N 1 ATOM 566 C CA . ALA A 1 77 ? 3.156 178.861 -0.029 1.00 20.20 ? 129 ALA A CA 1 ATOM 567 C C . ALA A 1 77 ? 3.959 178.446 1.195 1.00 20.39 ? 129 ALA A C 1 ATOM 568 O O . ALA A 1 77 ? 5.182 178.355 1.128 1.00 23.09 ? 129 ALA A O 1 ATOM 569 C CB . ALA A 1 77 ? 3.177 177.763 -1.071 1.00 21.10 ? 129 ALA A CB 1 ATOM 570 N N . LYS A 1 78 ? 3.279 178.198 2.308 1.00 18.21 ? 130 LYS A N 1 ATOM 571 C CA . LYS A 1 78 ? 3.966 177.718 3.499 1.00 18.38 ? 130 LYS A CA 1 ATOM 572 C C . LYS A 1 78 ? 4.066 176.200 3.454 1.00 18.03 ? 130 LYS A C 1 ATOM 573 O O . LYS A 1 78 ? 3.062 175.508 3.323 1.00 17.76 ? 130 LYS A O 1 ATOM 574 C CB . LYS A 1 78 ? 3.246 178.165 4.767 1.00 19.85 ? 130 LYS A CB 1 ATOM 575 C CG . LYS A 1 78 ? 3.947 177.736 6.042 1.00 24.87 ? 130 LYS A CG 1 ATOM 576 C CD . LYS A 1 78 ? 3.272 178.314 7.273 1.00 28.17 ? 130 LYS A CD 1 ATOM 577 C CE . LYS A 1 78 ? 3.966 177.849 8.543 1.00 42.60 ? 130 LYS A CE 1 ATOM 578 N NZ . LYS A 1 78 ? 3.396 178.488 9.759 1.00 47.85 ? 130 LYS A NZ 1 ATOM 579 N N . ILE A 1 79 ? 5.288 175.693 3.547 1.00 16.77 ? 131 ILE A N 1 ATOM 580 C CA . ILE A 1 79 ? 5.531 174.263 3.677 1.00 17.27 ? 131 ILE A CA 1 ATOM 581 C C . ILE A 1 79 ? 6.294 174.076 4.984 1.00 16.07 ? 131 ILE A C 1 ATOM 582 O O . ILE A 1 79 ? 7.222 174.829 5.261 1.00 16.34 ? 131 ILE A O 1 ATOM 583 C CB . ILE A 1 79 ? 6.323 173.707 2.488 1.00 15.78 ? 131 ILE A CB 1 ATOM 584 C CG1 . ILE A 1 79 ? 5.662 174.146 1.171 1.00 22.41 ? 131 ILE A CG1 1 ATOM 585 C CG2 . ILE A 1 79 ? 6.401 172.184 2.583 1.00 19.58 ? 131 ILE A CG2 1 ATOM 586 C CD1 . ILE A 1 79 ? 6.352 173.669 -0.045 1.00 29.69 ? 131 ILE A CD1 1 ATOM 587 N N . ASP A 1 80 ? 5.896 173.098 5.794 1.00 15.17 ? 132 ASP A N 1 ATOM 588 C CA . ASP A 1 80 ? 6.413 172.988 7.157 1.00 15.56 ? 132 ASP A CA 1 ATOM 589 C C . ASP A 1 80 ? 7.937 172.867 7.205 1.00 14.00 ? 132 ASP A C 1 ATOM 590 O O . ASP A 1 80 ? 8.574 173.343 8.143 1.00 14.68 ? 132 ASP A O 1 ATOM 591 C CB . ASP A 1 80 ? 5.762 171.802 7.886 1.00 15.56 ? 132 ASP A CB 1 ATOM 592 C CG . ASP A 1 80 ? 6.061 170.459 7.237 1.00 14.35 ? 132 ASP A CG 1 ATOM 593 O OD1 . ASP A 1 80 ? 5.459 170.129 6.182 1.00 14.31 ? 132 ASP A OD1 1 ATOM 594 O OD2 . ASP A 1 80 ? 6.875 169.715 7.812 1.00 13.57 ? 132 ASP A OD2 1 ATOM 595 N N . THR A 1 81 ? 8.523 172.260 6.182 1.00 11.77 ? 133 THR A N 1 ATOM 596 C CA . THR A 1 81 ? 9.975 172.086 6.114 1.00 11.67 ? 133 THR A CA 1 ATOM 597 C C . THR A 1 81 ? 10.755 173.392 5.883 1.00 12.81 ? 133 THR A C 1 ATOM 598 O O . THR A 1 81 ? 11.956 173.457 6.157 1.00 13.48 ? 133 THR A O 1 ATOM 599 C CB . THR A 1 81 ? 10.332 171.080 5.008 1.00 11.02 ? 133 THR A CB 1 ATOM 600 O OG1 . THR A 1 81 ? 9.532 171.367 3.853 1.00 12.44 ? 133 THR A OG1 1 ATOM 601 C CG2 . THR A 1 81 ? 10.042 169.655 5.491 1.00 11.05 ? 133 THR A CG2 1 ATOM 602 N N . LYS A 1 82 ? 10.100 174.436 5.388 1.00 12.47 ? 134 LYS A N 1 ATOM 603 C CA . LYS A 1 82 ? 10.802 175.712 5.224 1.00 14.50 ? 134 LYS A CA 1 ATOM 604 C C . LYS A 1 82 ? 11.331 176.189 6.572 1.00 18.05 ? 134 LYS A C 1 ATOM 605 O O . LYS A 1 82 ? 12.467 176.656 6.678 1.00 19.64 ? 134 LYS A O 1 ATOM 606 C CB . LYS A 1 82 ? 9.894 176.769 4.607 1.00 16.61 ? 134 LYS A CB 1 ATOM 607 C CG . LYS A 1 82 ? 9.669 176.543 3.142 1.00 24.96 ? 134 LYS A CG 1 ATOM 608 C CD . LYS A 1 82 ? 9.173 177.810 2.471 1.00 43.91 ? 134 LYS A CD 1 ATOM 609 C CE . LYS A 1 82 ? 7.781 177.636 1.936 1.00 28.57 ? 134 LYS A CE 1 ATOM 610 N NZ . LYS A 1 82 ? 7.531 178.599 0.815 1.00 44.47 ? 134 LYS A NZ 1 ATOM 611 N N . THR A 1 83 ? 10.518 176.028 7.603 1.00 14.70 ? 135 THR A N 1 ATOM 612 C CA . THR A 1 83 ? 10.894 176.441 8.950 1.00 16.64 ? 135 THR A CA 1 ATOM 613 C C . THR A 1 83 ? 11.857 175.465 9.612 1.00 16.06 ? 135 THR A C 1 ATOM 614 O O . THR A 1 83 ? 12.831 175.874 10.235 1.00 18.63 ? 135 THR A O 1 ATOM 615 C CB . THR A 1 83 ? 9.648 176.584 9.839 1.00 23.54 ? 135 THR A CB 1 ATOM 616 O OG1 . THR A 1 83 ? 8.822 177.633 9.324 1.00 29.90 ? 135 THR A OG1 1 ATOM 617 C CG2 . THR A 1 83 ? 10.023 176.903 11.293 1.00 25.35 ? 135 THR A CG2 1 ATOM 618 N N . THR A 1 84 ? 11.586 174.172 9.484 1.00 12.32 ? 136 THR A N 1 ATOM 619 C CA . THR A 1 84 ? 12.336 173.177 10.227 1.00 14.53 ? 136 THR A CA 1 ATOM 620 C C . THR A 1 84 ? 13.623 172.740 9.541 1.00 13.68 ? 136 THR A C 1 ATOM 621 O O . THR A 1 84 ? 14.554 172.309 10.216 1.00 13.63 ? 136 THR A O 1 ATOM 622 C CB . THR A 1 84 ? 11.488 171.933 10.460 1.00 12.63 ? 136 THR A CB 1 ATOM 623 O OG1 . THR A 1 84 ? 11.079 171.419 9.188 1.00 13.07 ? 136 THR A OG1 1 ATOM 624 C CG2 . THR A 1 84 ? 10.255 172.259 11.319 1.00 13.63 ? 136 THR A CG2 1 ATOM 625 N N . VAL A 1 85 ? 13.674 172.833 8.212 1.00 11.28 ? 137 VAL A N 1 ATOM 626 C CA . VAL A 1 85 ? 14.829 172.356 7.443 1.00 11.84 ? 137 VAL A CA 1 ATOM 627 C C . VAL A 1 85 ? 15.504 173.478 6.650 1.00 15.31 ? 137 VAL A C 1 ATOM 628 O O . VAL A 1 85 ? 16.715 173.431 6.419 1.00 21.35 ? 137 VAL A O 1 ATOM 629 C CB . VAL A 1 85 ? 14.421 171.218 6.470 1.00 11.93 ? 137 VAL A CB 1 ATOM 630 C CG1 . VAL A 1 85 ? 15.663 170.602 5.799 1.00 14.05 ? 137 VAL A CG1 1 ATOM 631 C CG2 . VAL A 1 85 ? 13.623 170.150 7.216 1.00 15.04 ? 137 VAL A CG2 1 ATOM 632 N N . GLY A 1 86 ? 14.736 174.485 6.246 1.00 14.17 ? 138 GLY A N 1 ATOM 633 C CA . GLY A 1 86 ? 15.292 175.641 5.559 1.00 18.08 ? 138 GLY A CA 1 ATOM 634 C C . GLY A 1 86 ? 15.022 175.682 4.069 1.00 17.64 ? 138 GLY A C 1 ATOM 635 O O . GLY A 1 86 ? 15.540 176.554 3.367 1.00 19.95 ? 138 GLY A O 1 ATOM 636 N N . ALA A 1 87 ? 14.214 174.751 3.580 1.00 15.82 ? 139 ALA A N 1 ATOM 637 C CA . ALA A 1 87 ? 13.872 174.677 2.165 1.00 16.34 ? 139 ALA A CA 1 ATOM 638 C C . ALA A 1 87 ? 12.483 174.079 2.046 1.00 14.34 ? 139 ALA A C 1 ATOM 639 O O . ALA A 1 87 ? 12.074 173.313 2.917 1.00 14.90 ? 139 ALA A O 1 ATOM 640 C CB . ALA A 1 87 ? 14.876 173.843 1.403 1.00 19.25 ? 139 ALA A CB 1 ATOM 641 N N . PRO A 1 88 ? 11.747 174.422 0.977 1.00 14.82 ? 140 PRO A N 1 ATOM 642 C CA . PRO A 1 88 ? 10.408 173.846 0.799 1.00 14.42 ? 140 PRO A CA 1 ATOM 643 C C . PRO A 1 88 ? 10.491 172.426 0.255 1.00 14.30 ? 140 PRO A C 1 ATOM 644 O O . PRO A 1 88 ? 10.491 172.195 -0.953 1.00 16.46 ? 140 PRO A O 1 ATOM 645 C CB . PRO A 1 88 ? 9.736 174.802 -0.187 1.00 17.15 ? 140 PRO A CB 1 ATOM 646 C CG . PRO A 1 88 ? 10.821 175.477 -0.891 1.00 23.06 ? 140 PRO A CG 1 ATOM 647 C CD . PRO A 1 88 ? 12.055 175.438 -0.042 1.00 19.85 ? 140 PRO A CD 1 ATOM 648 N N . TYR A 1 89 ? 10.609 171.489 1.186 1.00 13.53 ? 141 TYR A N 1 ATOM 649 C CA . TYR A 1 89 ? 10.799 170.078 0.882 1.00 10.64 ? 141 TYR A CA 1 ATOM 650 C C . TYR A 1 89 ? 9.541 169.239 1.109 1.00 11.25 ? 141 TYR A C 1 ATOM 651 O O . TYR A 1 89 ? 8.845 169.395 2.120 1.00 14.14 ? 141 TYR A O 1 ATOM 652 C CB . TYR A 1 89 ? 11.908 169.495 1.763 1.00 12.43 ? 141 TYR A CB 1 ATOM 653 C CG . TYR A 1 89 ? 13.340 169.836 1.410 1.00 14.46 ? 141 TYR A CG 1 ATOM 654 C CD1 . TYR A 1 89 ? 13.754 169.993 0.098 1.00 15.03 ? 141 TYR A CD1 1 ATOM 655 C CD2 . TYR A 1 89 ? 14.290 169.948 2.413 1.00 14.60 ? 141 TYR A CD2 1 ATOM 656 C CE1 . TYR A 1 89 ? 15.082 170.277 -0.199 1.00 18.67 ? 141 TYR A CE1 1 ATOM 657 C CE2 . TYR A 1 89 ? 15.605 170.230 2.130 1.00 14.84 ? 141 TYR A CE2 1 ATOM 658 C CZ . TYR A 1 89 ? 15.997 170.395 0.828 1.00 19.56 ? 141 TYR A CZ 1 ATOM 659 O OH . TYR A 1 89 ? 17.322 170.674 0.563 1.00 25.08 ? 141 TYR A OH 1 ATOM 660 N N . MET A 1 90 ? 9.284 168.320 0.182 1.00 12.20 ? 142 MET A N 1 ATOM 661 C CA . MET A 1 90 ? 8.355 167.221 0.433 1.00 10.84 ? 142 MET A CA 1 ATOM 662 C C . MET A 1 90 ? 9.127 165.992 0.913 1.00 12.07 ? 142 MET A C 1 ATOM 663 O O . MET A 1 90 ? 10.303 165.819 0.585 1.00 11.55 ? 142 MET A O 1 ATOM 664 C CB . MET A 1 90 ? 7.535 166.892 -0.824 1.00 11.98 ? 142 MET A CB 1 ATOM 665 C CG . MET A 1 90 ? 8.337 166.451 -2.024 1.00 11.67 ? 142 MET A CG 1 ATOM 666 S SD . MET A 1 90 ? 7.257 166.334 -3.475 1.00 14.68 ? 142 MET A SD 1 ATOM 667 C CE . MET A 1 90 ? 8.423 165.680 -4.660 1.00 15.58 ? 142 MET A CE 1 ATOM 668 N N . ALA A 1 91 ? 8.463 165.148 1.698 1.00 11.64 ? 143 ALA A N 1 ATOM 669 C CA . ALA A 1 91 ? 9.029 163.872 2.109 1.00 11.19 ? 143 ALA A CA 1 ATOM 670 C C . ALA A 1 91 ? 9.224 162.996 0.875 1.00 11.77 ? 143 ALA A C 1 ATOM 671 O O . ALA A 1 91 ? 8.314 162.866 0.050 1.00 13.55 ? 143 ALA A O 1 ATOM 672 C CB . ALA A 1 91 ? 8.127 163.183 3.125 1.00 12.38 ? 143 ALA A CB 1 ATOM 673 N N . ALA A 1 92 ? 10.404 162.399 0.746 1.00 10.87 ? 144 ALA A N 1 ATOM 674 C CA . ALA A 1 92 ? 10.794 161.689 -0.470 1.00 11.66 ? 144 ALA A CA 1 ATOM 675 C C . ALA A 1 92 ? 11.456 160.367 -0.138 1.00 10.71 ? 144 ALA A C 1 ATOM 676 O O . ALA A 1 92 ? 11.961 160.173 0.971 1.00 11.32 ? 144 ALA A O 1 ATOM 677 C CB . ALA A 1 92 ? 11.734 162.544 -1.298 1.00 15.11 ? 144 ALA A CB 1 ATOM 678 N N . GLY A 1 93 ? 11.463 159.475 -1.128 1.00 12.68 ? 145 GLY A N 1 ATOM 679 C CA . GLY A 1 93 ? 12.069 158.161 -1.008 1.00 11.55 ? 145 GLY A CA 1 ATOM 680 C C . GLY A 1 93 ? 11.100 157.113 -1.515 1.00 11.24 ? 145 GLY A C 1 ATOM 681 O O . GLY A 1 93 ? 10.049 156.902 -0.920 1.00 14.11 ? 145 GLY A O 1 ATOM 682 N N . ALA A 1 94 ? 11.454 156.448 -2.605 1.00 10.99 ? 146 ALA A N 1 ATOM 683 C CA . ALA A 1 94 ? 10.515 155.547 -3.279 1.00 11.42 ? 146 ALA A CA 1 ATOM 684 C C . ALA A 1 94 ? 10.214 154.239 -2.551 1.00 11.47 ? 146 ALA A C 1 ATOM 685 O O . ALA A 1 94 ? 9.188 153.624 -2.832 1.00 11.27 ? 146 ALA A O 1 ATOM 686 C CB . ALA A 1 94 ? 11.025 155.229 -4.671 1.00 11.09 ? 146 ALA A CB 1 ATOM 687 N N . CYS A 1 95 ? 11.086 153.802 -1.648 1.00 11.81 ? 147 CYS A N 1 ATOM 688 C CA . CYS A 1 95 ? 10.872 152.546 -0.925 1.00 10.07 ? 147 CYS A CA 1 ATOM 689 C C . CYS A 1 95 ? 10.147 152.774 0.390 1.00 12.67 ? 147 CYS A C 1 ATOM 690 O O . CYS A 1 95 ? 10.513 153.666 1.148 1.00 12.57 ? 147 CYS A O 1 ATOM 691 C CB . CYS A 1 95 ? 12.198 151.841 -0.639 1.00 11.72 ? 147 CYS A CB 1 ATOM 692 S SG . CYS A 1 95 ? 13.064 151.264 -2.113 1.00 14.75 ? 147 CYS A SG 1 ATOM 693 N N . PRO A 1 96 ? 9.139 151.939 0.693 1.00 10.60 ? 148 PRO A N 1 ATOM 694 C CA . PRO A 1 96 ? 8.550 151.964 2.030 1.00 10.78 ? 148 PRO A CA 1 ATOM 695 C C . PRO A 1 96 ? 9.601 151.691 3.101 1.00 10.97 ? 148 PRO A C 1 ATOM 696 O O . PRO A 1 96 ? 10.487 150.851 2.915 1.00 11.78 ? 148 PRO A O 1 ATOM 697 C CB . PRO A 1 96 ? 7.512 150.841 1.983 1.00 12.79 ? 148 PRO A CB 1 ATOM 698 C CG . PRO A 1 96 ? 7.211 150.667 0.543 1.00 11.77 ? 148 PRO A CG 1 ATOM 699 C CD . PRO A 1 96 ? 8.475 150.954 -0.181 1.00 10.81 ? 148 PRO A CD 1 ATOM 700 N N . ASN A 1 97 ? 9.498 152.408 4.213 1.00 11.17 ? 149 ASN A N 1 ATOM 701 C CA . ASN A 1 97 ? 10.503 152.326 5.259 1.00 11.22 ? 149 ASN A CA 1 ATOM 702 C C . ASN A 1 97 ? 9.895 151.638 6.466 1.00 10.72 ? 149 ASN A C 1 ATOM 703 O O . ASN A 1 97 ? 9.128 152.229 7.214 1.00 10.94 ? 149 ASN A O 1 ATOM 704 C CB . ASN A 1 97 ? 11.016 153.723 5.601 1.00 9.86 ? 149 ASN A CB 1 ATOM 705 C CG . ASN A 1 97 ? 12.341 153.695 6.310 1.00 11.43 ? 149 ASN A CG 1 ATOM 706 O OD1 . ASN A 1 97 ? 12.662 152.750 7.021 1.00 12.38 ? 149 ASN A OD1 1 ATOM 707 N ND2 . ASN A 1 97 ? 13.132 154.749 6.120 1.00 11.48 ? 149 ASN A ND2 1 ATOM 708 N N . TYR A 1 98 ? 10.203 150.356 6.608 1.00 10.93 ? 150 TYR A N 1 ATOM 709 C CA . TYR A 1 98 ? 9.552 149.540 7.622 1.00 10.78 ? 150 TYR A CA 1 ATOM 710 C C . TYR A 1 98 ? 10.083 149.822 9.023 1.00 12.44 ? 150 TYR A C 1 ATOM 711 O O . TYR A 1 98 ? 11.299 149.838 9.264 1.00 12.28 ? 150 TYR A O 1 ATOM 712 C CB . TYR A 1 98 ? 9.698 148.056 7.268 1.00 9.74 ? 150 TYR A CB 1 ATOM 713 C CG . TYR A 1 98 ? 8.992 147.717 5.970 1.00 10.87 ? 150 TYR A CG 1 ATOM 714 C CD1 . TYR A 1 98 ? 7.620 147.528 5.941 1.00 12.74 ? 150 TYR A CD1 1 ATOM 715 C CD2 . TYR A 1 98 ? 9.693 147.608 4.774 1.00 11.47 ? 150 TYR A CD2 1 ATOM 716 C CE1 . TYR A 1 98 ? 6.962 147.237 4.761 1.00 11.73 ? 150 TYR A CE1 1 ATOM 717 C CE2 . TYR A 1 98 ? 9.039 147.313 3.591 1.00 12.95 ? 150 TYR A CE2 1 ATOM 718 C CZ . TYR A 1 98 ? 7.675 147.132 3.596 1.00 13.19 ? 150 TYR A CZ 1 ATOM 719 O OH . TYR A 1 98 ? 7.029 146.842 2.416 1.00 14.29 ? 150 TYR A OH 1 ATOM 720 N N . GLY A 1 99 ? 9.156 150.056 9.937 1.00 11.83 ? 151 GLY A N 1 ATOM 721 C CA . GLY A 1 99 ? 9.464 150.319 11.327 1.00 10.84 ? 151 GLY A CA 1 ATOM 722 C C . GLY A 1 99 ? 9.605 151.796 11.646 1.00 11.19 ? 151 GLY A C 1 ATOM 723 O O . GLY A 1 99 ? 9.596 152.174 12.814 1.00 11.51 ? 151 GLY A O 1 ATOM 724 N N . LYS A 1 100 ? 9.726 152.635 10.620 1.00 10.06 ? 152 LYS A N 1 ATOM 725 C CA . LYS A 1 100 ? 9.992 154.060 10.822 1.00 10.69 ? 152 LYS A CA 1 ATOM 726 C C . LYS A 1 100 ? 8.768 154.822 11.318 1.00 10.27 ? 152 LYS A C 1 ATOM 727 O O . LYS A 1 100 ? 7.748 154.897 10.635 1.00 11.44 ? 152 LYS A O 1 ATOM 728 C CB . LYS A 1 100 ? 10.506 154.687 9.523 1.00 10.38 ? 152 LYS A CB 1 ATOM 729 C CG . LYS A 1 100 ? 10.686 156.211 9.553 1.00 9.79 ? 152 LYS A CG 1 ATOM 730 C CD . LYS A 1 100 ? 11.356 156.695 8.269 1.00 10.19 ? 152 LYS A CD 1 ATOM 731 C CE . LYS A 1 100 ? 11.368 158.210 8.131 1.00 10.02 ? 152 LYS A CE 1 ATOM 732 N NZ . LYS A 1 100 ? 12.142 158.638 6.933 1.00 10.33 ? 152 LYS A NZ 1 ATOM 733 N N . VAL A 1 101 ? 8.906 155.413 12.502 1.00 11.11 ? 153 VAL A N 1 ATOM 734 C CA . VAL A 1 101 ? 7.870 156.227 13.126 1.00 10.90 ? 153 VAL A CA 1 ATOM 735 C C . VAL A 1 101 ? 8.464 157.592 13.475 1.00 12.01 ? 153 VAL A C 1 ATOM 736 O O . VAL A 1 101 ? 9.619 157.668 13.909 1.00 11.85 ? 153 VAL A O 1 ATOM 737 C CB . VAL A 1 101 ? 7.327 155.540 14.403 1.00 13.23 ? 153 VAL A CB 1 ATOM 738 C CG1 . VAL A 1 101 ? 6.375 156.447 15.174 1.00 14.26 ? 153 VAL A CG1 1 ATOM 739 C CG2 . VAL A 1 101 ? 6.647 154.221 14.040 1.00 13.28 ? 153 VAL A CG2 1 ATOM 740 N N . ILE A 1 102 ? 7.687 158.652 13.294 1.00 10.81 ? 154 ILE A N 1 ATOM 741 C CA . ILE A 1 102 ? 8.107 159.978 13.730 1.00 11.06 ? 154 ILE A CA 1 ATOM 742 C C . ILE A 1 102 ? 7.777 160.144 15.204 1.00 10.40 ? 154 ILE A C 1 ATOM 743 O O . ILE A 1 102 ? 6.618 160.312 15.579 1.00 12.41 ? 154 ILE A O 1 ATOM 744 C CB . ILE A 1 102 ? 7.444 161.088 12.905 1.00 10.84 ? 154 ILE A CB 1 ATOM 745 C CG1 . ILE A 1 102 ? 7.664 160.851 11.406 1.00 12.10 ? 154 ILE A CG1 1 ATOM 746 C CG2 . ILE A 1 102 ? 7.997 162.443 13.326 1.00 11.46 ? 154 ILE A CG2 1 ATOM 747 C CD1 . ILE A 1 102 ? 9.124 160.611 10.990 1.00 13.70 ? 154 ILE A CD1 1 ATOM 748 N N . ALA A 1 103 ? 8.816 160.074 16.030 1.00 10.70 ? 155 ALA A N 1 ATOM 749 C CA . ALA A 1 103 ? 8.695 160.134 17.478 1.00 11.04 ? 155 ALA A CA 1 ATOM 750 C C . ALA A 1 103 ? 8.802 161.560 17.979 1.00 10.60 ? 155 ALA A C 1 ATOM 751 O O . ALA A 1 103 ? 9.618 162.340 17.482 1.00 11.64 ? 155 ALA A O 1 ATOM 752 C CB . ALA A 1 103 ? 9.779 159.282 18.126 1.00 11.14 ? 155 ALA A CB 1 ATOM 753 N N . PHE A 1 104 ? 7.980 161.895 18.961 1.00 9.26 ? 156 PHE A N 1 ATOM 754 C CA . PHE A 1 104 ? 8.102 163.159 19.677 1.00 9.02 ? 156 PHE A CA 1 ATOM 755 C C . PHE A 1 104 ? 9.085 162.928 20.812 1.00 11.71 ? 156 PHE A C 1 ATOM 756 O O . PHE A 1 104 ? 8.944 161.966 21.557 1.00 11.61 ? 156 PHE A O 1 ATOM 757 C CB . PHE A 1 104 ? 6.757 163.631 20.208 1.00 9.77 ? 156 PHE A CB 1 ATOM 758 C CG . PHE A 1 104 ? 5.892 164.289 19.168 1.00 9.74 ? 156 PHE A CG 1 ATOM 759 C CD1 . PHE A 1 104 ? 5.508 163.609 18.023 1.00 11.14 ? 156 PHE A CD1 1 ATOM 760 C CD2 . PHE A 1 104 ? 5.450 165.593 19.340 1.00 11.50 ? 156 PHE A CD2 1 ATOM 761 C CE1 . PHE A 1 104 ? 4.712 164.233 17.065 1.00 10.56 ? 156 PHE A CE1 1 ATOM 762 C CE2 . PHE A 1 104 ? 4.644 166.207 18.388 1.00 11.82 ? 156 PHE A CE2 1 ATOM 763 C CZ . PHE A 1 104 ? 4.285 165.527 17.260 1.00 10.29 ? 156 PHE A CZ 1 ATOM 764 N N . THR A 1 105 ? 10.093 163.787 20.918 1.00 10.73 ? 157 THR A N 1 ATOM 765 C CA . THR A 1 105 ? 11.178 163.592 21.873 1.00 10.90 ? 157 THR A CA 1 ATOM 766 C C . THR A 1 105 ? 11.587 164.894 22.554 1.00 11.04 ? 157 THR A C 1 ATOM 767 O O . THR A 1 105 ? 11.132 165.980 22.196 1.00 12.15 ? 157 THR A O 1 ATOM 768 C CB . THR A 1 105 ? 12.435 162.998 21.175 1.00 11.74 ? 157 THR A CB 1 ATOM 769 O OG1 . THR A 1 105 ? 13.032 163.994 20.336 1.00 14.11 ? 157 THR A OG1 1 ATOM 770 C CG2 . THR A 1 105 ? 12.080 161.797 20.316 1.00 12.05 ? 157 THR A CG2 1 ATOM 771 N N . LYS A 1 106 ? 12.471 164.775 23.538 1.00 11.10 ? 158 LYS A N 1 ATOM 772 C CA . LYS A 1 106 ? 13.221 165.933 23.990 1.00 11.79 ? 158 LYS A CA 1 ATOM 773 C C . LYS A 1 106 ? 14.317 166.205 22.965 1.00 11.59 ? 158 LYS A C 1 ATOM 774 O O . LYS A 1 106 ? 14.543 165.405 22.054 1.00 13.63 ? 158 LYS A O 1 ATOM 775 C CB . LYS A 1 106 ? 13.787 165.700 25.384 1.00 12.91 ? 158 LYS A CB 1 ATOM 776 C CG . LYS A 1 106 ? 12.681 165.573 26.411 1.00 15.28 ? 158 LYS A CG 1 ATOM 777 C CD . LYS A 1 106 ? 13.177 165.736 27.818 1.00 24.54 ? 158 LYS A CD 1 ATOM 778 C CE . LYS A 1 106 ? 13.597 167.172 28.092 1.00 24.04 ? 158 LYS A CE 1 ATOM 779 N NZ . LYS A 1 106 ? 14.025 167.363 29.498 1.00 32.89 ? 158 LYS A NZ 1 ATOM 780 N N . ARG A 1 107 ? 14.997 167.334 23.105 1.00 14.35 ? 159 ARG A N 1 ATOM 781 C CA . ARG A 1 107 ? 15.992 167.734 22.118 1.00 13.56 ? 159 ARG A CA 1 ATOM 782 C C . ARG A 1 107 ? 17.157 166.749 22.036 1.00 13.12 ? 159 ARG A C 1 ATOM 783 O O . ARG A 1 107 ? 17.816 166.656 21.001 1.00 13.11 ? 159 ARG A O 1 ATOM 784 C CB . ARG A 1 107 ? 16.504 169.138 22.442 1.00 13.83 ? 159 ARG A CB 1 ATOM 785 C CG . ARG A 1 107 ? 17.246 169.806 21.300 1.00 16.33 ? 159 ARG A CG 1 ATOM 786 C CD . ARG A 1 107 ? 17.464 171.292 21.554 1.00 17.52 ? 159 ARG A CD 1 ATOM 787 N NE . ARG A 1 107 ? 16.191 171.985 21.700 1.00 16.37 ? 159 ARG A NE 1 ATOM 788 C CZ . ARG A 1 107 ? 15.746 172.567 22.810 1.00 18.93 ? 159 ARG A CZ 1 ATOM 789 N NH1 . ARG A 1 107 ? 16.475 172.597 23.920 1.00 24.19 ? 159 ARG A NH1 1 ATOM 790 N NH2 . ARG A 1 107 ? 14.556 173.138 22.806 1.00 17.93 ? 159 ARG A NH2 1 ATOM 791 N N . ASP A 1 108 ? 17.408 166.012 23.116 1.00 12.72 ? 160 ASP A N 1 ATOM 792 C CA . ASP A 1 108 ? 18.462 165.008 23.109 1.00 12.53 ? 160 ASP A CA 1 ATOM 793 C C . ASP A 1 108 ? 17.952 163.619 22.725 1.00 13.01 ? 160 ASP A C 1 ATOM 794 O O . ASP A 1 108 ? 18.667 162.626 22.849 1.00 13.50 ? 160 ASP A O 1 ATOM 795 C CB . ASP A 1 108 ? 19.167 164.962 24.475 1.00 13.51 ? 160 ASP A CB 1 ATOM 796 C CG . ASP A 1 108 ? 18.261 164.516 25.607 1.00 19.94 ? 160 ASP A CG 1 ATOM 797 O OD1 . ASP A 1 108 ? 17.059 164.279 25.369 1.00 15.93 ? 160 ASP A OD1 1 ATOM 798 O OD2 . ASP A 1 108 ? 18.758 164.418 26.753 1.00 21.57 ? 160 ASP A OD2 1 ATOM 799 N N . GLY A 1 109 ? 16.715 163.547 22.238 1.00 12.09 ? 161 GLY A N 1 ATOM 800 C CA . GLY A 1 109 ? 16.152 162.276 21.812 1.00 12.58 ? 161 GLY A CA 1 ATOM 801 C C . GLY A 1 109 ? 15.504 161.447 22.913 1.00 13.84 ? 161 GLY A C 1 ATOM 802 O O . GLY A 1 109 ? 14.933 160.395 22.623 1.00 14.08 ? 161 GLY A O 1 ATOM 803 N N . SER A 1 110 ? 15.589 161.906 24.161 1.00 11.57 ? 162 SER A N 1 ATOM 804 C CA . SER A 1 110 ? 15.062 161.156 25.298 1.00 13.00 ? 162 SER A CA 1 ATOM 805 C C . SER A 1 110 ? 13.557 161.339 25.460 1.00 11.59 ? 162 SER A C 1 ATOM 806 O O . SER A 1 110 ? 12.956 162.223 24.847 1.00 12.62 ? 162 SER A O 1 ATOM 807 C CB . SER A 1 110 ? 15.782 161.562 26.602 1.00 13.45 ? 162 SER A CB 1 ATOM 808 O OG . SER A 1 110 ? 15.480 162.881 27.011 1.00 15.26 ? 162 SER A OG 1 ATOM 809 N N . ARG A 1 111 ? 12.966 160.475 26.283 1.00 13.10 ? 163 ARG A N 1 ATOM 810 C CA . ARG A 1 111 ? 11.543 160.519 26.627 1.00 13.31 ? 163 ARG A CA 1 ATOM 811 C C . ARG A 1 111 ? 10.693 160.470 25.373 1.00 13.17 ? 163 ARG A C 1 ATOM 812 O O . ARG A 1 111 ? 9.694 161.177 25.251 1.00 15.02 ? 163 ARG A O 1 ATOM 813 C CB . ARG A 1 111 ? 11.225 161.759 27.464 1.00 14.08 ? 163 ARG A CB 1 ATOM 814 C CG . ARG A 1 111 ? 12.200 161.898 28.634 1.00 18.28 ? 163 ARG A CG 1 ATOM 815 C CD . ARG A 1 111 ? 11.648 162.631 29.818 1.00 23.61 ? 163 ARG A CD 1 ATOM 816 N NE . ARG A 1 111 ? 12.655 162.696 30.882 1.00 26.00 ? 163 ARG A NE 1 ATOM 817 C CZ . ARG A 1 111 ? 12.858 161.752 31.800 1.00 24.73 ? 163 ARG A CZ 1 ATOM 818 N NH1 . ARG A 1 111 ? 12.116 160.650 31.818 1.00 26.89 ? 163 ARG A NH1 1 ATOM 819 N NH2 . ARG A 1 111 ? 13.810 161.915 32.716 1.00 23.87 ? 163 ARG A NH2 1 ATOM 820 N N . SER A 1 112 ? 11.085 159.596 24.459 1.00 13.96 ? 164 SER A N 1 ATOM 821 C CA . SER A 1 112 ? 10.425 159.505 23.175 1.00 14.12 ? 164 SER A CA 1 ATOM 822 C C . SER A 1 112 ? 9.025 158.941 23.327 1.00 15.54 ? 164 SER A C 1 ATOM 823 O O . SER A 1 112 ? 8.767 158.082 24.176 1.00 17.14 ? 164 SER A O 1 ATOM 824 C CB . SER A 1 112 ? 11.235 158.652 22.207 1.00 15.74 ? 164 SER A CB 1 ATOM 825 O OG . SER A 1 112 ? 11.433 157.347 22.714 1.00 17.80 ? 164 SER A OG 1 ATOM 826 N N . ASP A 1 113 ? 8.135 159.452 22.488 1.00 11.97 ? 165 ASP A N 1 ATOM 827 C CA . ASP A 1 113 ? 6.734 159.043 22.449 1.00 13.87 ? 165 ASP A CA 1 ATOM 828 C C . ASP A 1 113 ? 6.431 158.634 21.014 1.00 13.17 ? 165 ASP A C 1 ATOM 829 O O . ASP A 1 113 ? 6.399 159.482 20.123 1.00 13.57 ? 165 ASP A O 1 ATOM 830 C CB . ASP A 1 113 ? 5.836 160.189 22.906 1.00 14.73 ? 165 ASP A CB 1 ATOM 831 C CG . ASP A 1 113 ? 4.368 159.813 22.955 1.00 17.62 ? 165 ASP A CG 1 ATOM 832 O OD1 . ASP A 1 113 ? 3.950 158.871 22.247 1.00 17.20 ? 165 ASP A OD1 1 ATOM 833 O OD2 . ASP A 1 113 ? 3.623 160.481 23.700 1.00 19.61 ? 165 ASP A OD2 1 ATOM 834 N N . MET A 1 114 ? 6.219 157.340 20.793 1.00 12.81 ? 166 MET A N 1 ATOM 835 C CA . MET A 1 114 ? 6.059 156.833 19.443 1.00 13.23 ? 166 MET A CA 1 ATOM 836 C C . MET A 1 114 ? 4.597 156.660 19.012 1.00 14.17 ? 166 MET A C 1 ATOM 837 O O . MET A 1 114 ? 4.344 156.109 17.943 1.00 14.09 ? 166 MET A O 1 ATOM 838 C CB . MET A 1 114 ? 6.823 155.518 19.305 1.00 19.27 ? 166 MET A CB 1 ATOM 839 C CG . MET A 1 114 ? 8.327 155.800 19.125 1.00 20.92 ? 166 MET A CG 1 ATOM 840 S SD . MET A 1 114 ? 9.347 154.354 19.076 1.00 26.57 ? 166 MET A SD 1 ATOM 841 C CE . MET A 1 114 ? 8.934 153.719 17.448 1.00 15.35 ? 166 MET A CE 1 ATOM 842 N N . THR A 1 115 ? 3.652 157.156 19.810 1.00 14.02 ? 167 THR A N 1 ATOM 843 C CA . THR A 1 115 ? 2.238 157.145 19.406 1.00 14.51 ? 167 THR A CA 1 ATOM 844 C C . THR A 1 115 ? 1.622 158.546 19.336 1.00 12.92 ? 167 THR A C 1 ATOM 845 O O . THR A 1 115 ? 0.509 158.724 18.838 1.00 13.89 ? 167 THR A O 1 ATOM 846 C CB . THR A 1 115 ? 1.369 156.276 20.350 1.00 18.00 ? 167 THR A CB 1 ATOM 847 O OG1 . THR A 1 115 ? 1.417 156.790 21.680 1.00 22.09 ? 167 THR A OG1 1 ATOM 848 C CG2 . THR A 1 115 ? 1.844 154.823 20.339 1.00 22.91 ? 167 THR A CG2 1 ATOM 849 N N . ARG A 1 116 ? 2.343 159.546 19.824 1.00 12.12 ? 168 ARG A N 1 ATOM 850 C CA . ARG A 1 116 ? 1.883 160.922 19.777 1.00 12.61 ? 168 ARG A CA 1 ATOM 851 C C . ARG A 1 116 ? 1.542 161.376 18.348 1.00 12.29 ? 168 ARG A C 1 ATOM 852 O O . ARG A 1 116 ? 0.639 162.195 18.156 1.00 11.46 ? 168 ARG A O 1 ATOM 853 C CB . ARG A 1 116 ? 2.955 161.828 20.407 1.00 13.00 ? 168 ARG A CB 1 ATOM 854 C CG . ARG A 1 116 ? 2.704 163.307 20.313 1.00 12.80 ? 168 ARG A CG 1 ATOM 855 C CD . ARG A 1 116 ? 1.575 163.807 21.213 1.00 13.94 ? 168 ARG A CD 1 ATOM 856 N NE . ARG A 1 116 ? 1.625 165.255 21.119 1.00 13.96 ? 168 ARG A NE 1 ATOM 857 C CZ . ARG A 1 116 ? 2.359 166.050 21.891 1.00 13.36 ? 168 ARG A CZ 1 ATOM 858 N NH1 . ARG A 1 116 ? 3.036 165.566 22.929 1.00 13.69 ? 168 ARG A NH1 1 ATOM 859 N NH2 . ARG A 1 116 ? 2.382 167.343 21.636 1.00 13.70 ? 168 ARG A NH2 1 ATOM 860 N N . TRP A 1 117 ? 2.251 160.844 17.353 1.00 11.11 ? 169 TRP A N 1 ATOM 861 C CA . TRP A 1 117 ? 2.043 161.251 15.963 1.00 9.79 ? 169 TRP A CA 1 ATOM 862 C C . TRP A 1 117 ? 0.599 161.063 15.500 1.00 9.21 ? 169 TRP A C 1 ATOM 863 O O . TRP A 1 117 ? 0.167 161.726 14.563 1.00 10.41 ? 169 TRP A O 1 ATOM 864 C CB . TRP A 1 117 ? 2.988 160.483 15.022 1.00 10.56 ? 169 TRP A CB 1 ATOM 865 C CG . TRP A 1 117 ? 2.673 159.020 14.879 1.00 10.15 ? 169 TRP A CG 1 ATOM 866 C CD1 . TRP A 1 117 ? 3.202 157.998 15.601 1.00 10.62 ? 169 TRP A CD1 1 ATOM 867 C CD2 . TRP A 1 117 ? 1.741 158.425 13.960 1.00 10.66 ? 169 TRP A CD2 1 ATOM 868 N NE1 . TRP A 1 117 ? 2.661 156.797 15.192 1.00 13.20 ? 169 TRP A NE1 1 ATOM 869 C CE2 . TRP A 1 117 ? 1.764 157.036 14.183 1.00 11.84 ? 169 TRP A CE2 1 ATOM 870 C CE3 . TRP A 1 117 ? 0.907 158.935 12.963 1.00 12.97 ? 169 TRP A CE3 1 ATOM 871 C CZ2 . TRP A 1 117 ? 0.973 156.146 13.450 1.00 14.48 ? 169 TRP A CZ2 1 ATOM 872 C CZ3 . TRP A 1 117 ? 0.118 158.047 12.238 1.00 14.08 ? 169 TRP A CZ3 1 ATOM 873 C CH2 . TRP A 1 117 ? 0.160 156.675 12.485 1.00 14.38 ? 169 TRP A CH2 1 ATOM 874 N N . LYS A 1 118 ? -0.141 160.181 16.161 1.00 10.71 ? 170 LYS A N 1 ATOM 875 C CA . LYS A 1 118 ? -1.504 159.869 15.731 1.00 12.16 ? 170 LYS A CA 1 ATOM 876 C C . LYS A 1 118 ? -2.488 161.003 15.958 1.00 12.15 ? 170 LYS A C 1 ATOM 877 O O . LYS A 1 118 ? -3.550 161.028 15.330 1.00 12.76 ? 170 LYS A O 1 ATOM 878 C CB . LYS A 1 118 ? -2.004 158.613 16.441 1.00 12.74 ? 170 LYS A CB 1 ATOM 879 C CG . LYS A 1 118 ? -1.251 157.378 16.033 1.00 14.17 ? 170 LYS A CG 1 ATOM 880 C CD . LYS A 1 118 ? -1.807 156.149 16.720 1.00 17.95 ? 170 LYS A CD 1 ATOM 881 C CE . LYS A 1 118 ? -1.000 154.919 16.372 1.00 28.53 ? 170 LYS A CE 1 ATOM 882 N NZ . LYS A 1 118 ? -1.488 153.727 17.111 1.00 33.73 ? 170 LYS A NZ 1 ATOM 883 N N . ASN A 1 119 ? -2.175 161.920 16.867 1.00 11.54 ? 171 ASN A N 1 ATOM 884 C CA . ASN A 1 119 ? -3.018 163.104 17.039 1.00 12.31 ? 171 ASN A CA 1 ATOM 885 C C . ASN A 1 119 ? -2.900 163.997 15.813 1.00 11.46 ? 171 ASN A C 1 ATOM 886 O O . ASN A 1 119 ? -1.860 164.015 15.152 1.00 11.13 ? 171 ASN A O 1 ATOM 887 C CB . ASN A 1 119 ? -2.628 163.900 18.281 1.00 11.62 ? 171 ASN A CB 1 ATOM 888 C CG . ASN A 1 119 ? -2.779 163.115 19.567 1.00 13.38 ? 171 ASN A CG 1 ATOM 889 O OD1 . ASN A 1 119 ? -3.244 161.974 19.579 1.00 14.33 ? 171 ASN A OD1 1 ATOM 890 N ND2 . ASN A 1 119 ? -2.366 163.733 20.672 1.00 14.63 ? 171 ASN A ND2 1 ATOM 891 N N . GLU A 1 120 ? -3.953 164.742 15.492 1.00 12.70 ? 172 GLU A N 1 ATOM 892 C CA . GLU A 1 120 ? -3.886 165.634 14.349 1.00 11.05 ? 172 GLU A CA 1 ATOM 893 C C . GLU A 1 120 ? -2.920 166.791 14.565 1.00 11.71 ? 172 GLU A C 1 ATOM 894 O O . GLU A 1 120 ? -2.573 167.146 15.697 1.00 12.50 ? 172 GLU A O 1 ATOM 895 C CB . GLU A 1 120 ? -5.268 166.193 14.014 1.00 14.16 ? 172 GLU A CB 1 ATOM 896 C CG . GLU A 1 120 ? -6.156 165.207 13.288 1.00 12.49 ? 172 GLU A CG 1 ATOM 897 C CD . GLU A 1 120 ? -7.443 165.836 12.791 1.00 12.54 ? 172 GLU A CD 1 ATOM 898 O OE1 . GLU A 1 120 ? -7.610 167.061 12.940 1.00 12.78 ? 172 GLU A OE1 1 ATOM 899 O OE2 . GLU A 1 120 ? -8.285 165.094 12.255 1.00 14.25 ? 172 GLU A OE2 1 ATOM 900 N N . ILE A 1 121 ? -2.505 167.386 13.455 1.00 11.18 ? 173 ILE A N 1 ATOM 901 C CA . ILE A 1 121 ? -1.695 168.597 13.472 1.00 11.39 ? 173 ILE A CA 1 ATOM 902 C C . ILE A 1 121 ? -2.484 169.817 13.923 1.00 13.55 ? 173 ILE A C 1 ATOM 903 O O . ILE A 1 121 ? -3.722 169.806 13.960 1.00 13.31 ? 173 ILE A O 1 ATOM 904 C CB . ILE A 1 121 ? -1.086 168.877 12.069 1.00 11.76 ? 173 ILE A CB 1 ATOM 905 C CG1 . ILE A 1 121 ? -2.188 169.190 11.035 1.00 12.10 ? 173 ILE A CG1 1 ATOM 906 C CG2 . ILE A 1 121 ? -0.241 167.691 11.623 1.00 12.99 ? 173 ILE A CG2 1 ATOM 907 C CD1 . ILE A 1 121 ? -1.661 169.568 9.645 1.00 13.49 ? 173 ILE A CD1 1 ATOM 908 N N . HIS A 1 122 ? -1.746 170.869 14.267 1.00 14.88 ? 174 HIS A N 1 ATOM 909 C CA . HIS A 1 122 ? -2.306 172.179 14.561 1.00 13.51 ? 174 HIS A CA 1 ATOM 910 C C . HIS A 1 122 ? -1.578 173.196 13.682 1.00 13.53 ? 174 HIS A C 1 ATOM 911 O O . HIS A 1 122 ? -0.734 173.951 14.163 1.00 16.48 ? 174 HIS A O 1 ATOM 912 C CB . HIS A 1 122 ? -2.157 172.530 16.044 1.00 15.75 ? 174 HIS A CB 1 ATOM 913 C CG . HIS A 1 122 ? -2.853 173.797 16.436 1.00 12.85 ? 174 HIS A CG 1 ATOM 914 N ND1 . HIS A 1 122 ? -3.909 173.817 17.321 1.00 16.53 ? 174 HIS A ND1 1 ATOM 915 C CD2 . HIS A 1 122 ? -2.674 175.080 16.039 1.00 16.67 ? 174 HIS A CD2 1 ATOM 916 C CE1 . HIS A 1 122 ? -4.341 175.059 17.463 1.00 16.51 ? 174 HIS A CE1 1 ATOM 917 N NE2 . HIS A 1 122 ? -3.612 175.845 16.691 1.00 16.22 ? 174 HIS A NE2 1 ATOM 918 N N . ALA A 1 123 ? -1.889 173.204 12.389 1.00 13.36 ? 175 ALA A N 1 ATOM 919 C CA . ALA A 1 123 ? -1.189 174.090 11.462 1.00 12.15 ? 175 ALA A CA 1 ATOM 920 C C . ALA A 1 123 ? -1.908 175.427 11.247 1.00 15.12 ? 175 ALA A C 1 ATOM 921 O O . ALA A 1 123 ? -1.555 176.177 10.339 1.00 16.84 ? 175 ALA A O 1 ATOM 922 C CB . ALA A 1 123 ? -0.980 173.388 10.120 1.00 14.03 ? 175 ALA A CB 1 ATOM 923 N N . ASN A 1 124 ? -2.900 175.725 12.087 1.00 15.43 ? 176 ASN A N 1 ATOM 924 C CA . ASN A 1 124 ? -3.652 176.982 12.018 1.00 16.07 ? 176 ASN A CA 1 ATOM 925 C C . ASN A 1 124 ? -4.394 177.101 10.683 1.00 14.75 ? 176 ASN A C 1 ATOM 926 O O . ASN A 1 124 ? -4.266 178.096 9.961 1.00 19.33 ? 176 ASN A O 1 ATOM 927 C CB . ASN A 1 124 ? -2.728 178.180 12.242 1.00 16.86 ? 176 ASN A CB 1 ATOM 928 C CG . ASN A 1 124 ? -2.045 178.139 13.598 1.00 23.95 ? 176 ASN A CG 1 ATOM 929 O OD1 . ASN A 1 124 ? -2.702 177.983 14.627 1.00 27.20 ? 176 ASN A OD1 1 ATOM 930 N ND2 . ASN A 1 124 ? -0.723 178.253 13.601 1.00 31.06 ? 176 ASN A ND2 1 ATOM 931 N N . VAL A 1 125 ? -5.177 176.068 10.385 1.00 14.13 ? 177 VAL A N 1 ATOM 932 C CA . VAL A 1 125 ? -5.921 175.956 9.133 1.00 14.73 ? 177 VAL A CA 1 ATOM 933 C C . VAL A 1 125 ? -7.437 175.932 9.358 1.00 14.91 ? 177 VAL A C 1 ATOM 934 O O . VAL A 1 125 ? -8.165 176.622 8.648 1.00 16.36 ? 177 VAL A O 1 ATOM 935 C CB . VAL A 1 125 ? -5.511 174.682 8.364 1.00 15.04 ? 177 VAL A CB 1 ATOM 936 C CG1 . VAL A 1 125 ? -6.382 174.465 7.123 1.00 18.01 ? 177 VAL A CG1 1 ATOM 937 C CG2 . VAL A 1 125 ? -4.039 174.767 7.963 1.00 14.55 ? 177 VAL A CG2 1 ATOM 938 N N . MET A 1 126 ? -7.897 175.148 10.337 1.00 14.34 ? 178 MET A N 1 ATOM 939 C CA . MET A 1 126 ? -9.329 174.899 10.541 1.00 15.00 ? 178 MET A CA 1 ATOM 940 C C . MET A 1 126 ? -9.885 175.755 11.677 1.00 14.41 ? 178 MET A C 1 ATOM 941 O O . MET A 1 126 ? -9.329 175.765 12.770 1.00 14.97 ? 178 MET A O 1 ATOM 942 C CB . MET A 1 126 ? -9.586 173.418 10.853 1.00 14.44 ? 178 MET A CB 1 ATOM 943 C CG . MET A 1 126 ? -9.079 172.443 9.791 1.00 14.94 ? 178 MET A CG 1 ATOM 944 S SD . MET A 1 126 ? -9.820 172.744 8.170 1.00 15.74 ? 178 MET A SD 1 ATOM 945 C CE . MET A 1 126 ? -9.114 171.388 7.224 1.00 17.37 ? 178 MET A CE 1 ATOM 946 N N . PRO A 1 127 ? -11.005 176.452 11.440 1.00 13.39 ? 179 PRO A N 1 ATOM 947 C CA . PRO A 1 127 ? -11.810 176.488 10.214 1.00 16.04 ? 179 PRO A CA 1 ATOM 948 C C . PRO A 1 127 ? -11.185 177.358 9.137 1.00 14.77 ? 179 PRO A C 1 ATOM 949 O O . PRO A 1 127 ? -10.641 178.419 9.435 1.00 16.72 ? 179 PRO A O 1 ATOM 950 C CB . PRO A 1 127 ? -13.131 177.090 10.685 1.00 13.58 ? 179 PRO A CB 1 ATOM 951 C CG . PRO A 1 127 ? -12.714 178.016 11.783 1.00 15.99 ? 179 PRO A CG 1 ATOM 952 C CD . PRO A 1 127 ? -11.606 177.280 12.499 1.00 15.27 ? 179 PRO A CD 1 ATOM 953 N N . HIS A 1 128 ? -11.275 176.913 7.892 1.00 15.94 ? 180 HIS A N 1 ATOM 954 C CA . HIS A 1 128 ? -10.718 177.674 6.790 1.00 15.28 ? 180 HIS A CA 1 ATOM 955 C C . HIS A 1 128 ? -11.637 178.825 6.415 1.00 16.92 ? 180 HIS A C 1 ATOM 956 O O . HIS A 1 128 ? -11.180 179.885 6.000 1.00 18.15 ? 180 HIS A O 1 ATOM 957 C CB . HIS A 1 128 ? -10.484 176.760 5.589 1.00 15.49 ? 180 HIS A CB 1 ATOM 958 C CG . HIS A 1 128 ? -9.864 177.455 4.424 1.00 17.75 ? 180 HIS A CG 1 ATOM 959 N ND1 . HIS A 1 128 ? -8.564 177.911 4.438 1.00 17.46 ? 180 HIS A ND1 1 ATOM 960 C CD2 . HIS A 1 128 ? -10.374 177.802 3.220 1.00 16.61 ? 180 HIS A CD2 1 ATOM 961 C CE1 . HIS A 1 128 ? -8.296 178.499 3.287 1.00 17.20 ? 180 HIS A CE1 1 ATOM 962 N NE2 . HIS A 1 128 ? -9.377 178.447 2.531 1.00 18.18 ? 180 HIS A NE2 1 ATOM 963 N N . SER A 1 129 ? -12.938 178.596 6.567 1.00 16.96 ? 181 SER A N 1 ATOM 964 C CA . SER A 1 129 ? -13.946 179.619 6.306 1.00 20.01 ? 181 SER A CA 1 ATOM 965 C C . SER A 1 129 ? -15.045 179.523 7.348 1.00 13.93 ? 181 SER A C 1 ATOM 966 O O . SER A 1 129 ? -15.355 178.438 7.839 1.00 17.54 ? 181 SER A O 1 ATOM 967 C CB . SER A 1 129 ? -14.539 179.464 4.903 1.00 20.82 ? 181 SER A CB 1 ATOM 968 O OG . SER A 1 129 ? -15.648 180.335 4.720 1.00 22.54 ? 181 SER A OG 1 ATOM 969 N N . THR A 1 130 ? -15.621 180.668 7.691 1.00 16.99 ? 182 THR A N 1 ATOM 970 C CA . THR A 1 130 ? -16.802 180.700 8.542 1.00 17.87 ? 182 THR A CA 1 ATOM 971 C C . THR A 1 130 ? -17.908 181.487 7.855 1.00 20.11 ? 182 THR A C 1 ATOM 972 O O . THR A 1 130 ? -18.780 182.038 8.513 1.00 19.45 ? 182 THR A O 1 ATOM 973 C CB . THR A 1 130 ? -16.504 181.323 9.923 1.00 19.51 ? 182 THR A CB 1 ATOM 974 O OG1 . THR A 1 130 ? -15.973 182.643 9.754 1.00 19.74 ? 182 THR A OG1 1 ATOM 975 C CG2 . THR A 1 130 ? -15.508 180.471 10.688 1.00 18.17 ? 182 THR A CG2 1 ATOM 976 N N . THR A 1 131 ? -17.878 181.518 6.528 1.00 17.02 ? 183 THR A N 1 ATOM 977 C CA . THR A 1 131 ? -18.869 182.269 5.764 1.00 18.85 ? 183 THR A CA 1 ATOM 978 C C . THR A 1 131 ? -20.289 181.831 6.118 1.00 18.91 ? 183 THR A C 1 ATOM 979 O O . THR A 1 131 ? -20.604 180.640 6.103 1.00 18.30 ? 183 THR A O 1 ATOM 980 C CB . THR A 1 131 ? -18.616 182.110 4.262 1.00 20.95 ? 183 THR A CB 1 ATOM 981 O OG1 . THR A 1 131 ? -17.363 182.726 3.946 1.00 22.43 ? 183 THR A OG1 1 ATOM 982 C CG2 . THR A 1 131 ? -19.718 182.769 3.425 1.00 21.06 ? 183 THR A CG2 1 ATOM 983 N N . SER A 1 132 ? -21.105 182.829 6.465 1.00 19.10 ? 184 SER A N 1 ATOM 984 C CA . SER A 1 132 ? -22.530 182.698 6.807 1.00 19.89 ? 184 SER A CA 1 ATOM 985 C C . SER A 1 132 ? -22.772 182.290 8.267 1.00 20.42 ? 184 SER A C 1 ATOM 986 O O . SER A 1 132 ? -23.920 182.260 8.721 1.00 21.64 ? 184 SER A O 1 ATOM 987 C CB . SER A 1 132 ? -23.234 181.713 5.868 1.00 19.52 ? 184 SER A CB 1 ATOM 988 O OG . SER A 1 132 ? -23.140 180.374 6.312 1.00 22.33 ? 184 SER A OG 1 ATOM 989 N N . CYS A 1 133 ? -21.703 181.989 8.999 1.00 18.48 ? 185 CYS A N 1 ATOM 990 C CA . CYS A 1 133 ? -21.823 181.630 10.412 1.00 21.68 ? 185 CYS A CA 1 ATOM 991 C C . CYS A 1 133 ? -22.208 182.837 11.262 1.00 18.15 ? 185 CYS A C 1 ATOM 992 O O . CYS A 1 133 ? -21.898 183.971 10.918 1.00 21.65 ? 185 CYS A O 1 ATOM 993 C CB . CYS A 1 133 ? -20.511 181.043 10.941 1.00 20.51 ? 185 CYS A CB 1 ATOM 994 S SG . CYS A 1 133 ? -19.992 179.509 10.134 1.00 19.47 ? 185 CYS A SG 1 ATOM 995 N N . ALA A 1 134 ? -22.867 182.577 12.385 1.00 18.36 ? 186 ALA A N 1 ATOM 996 C CA . ALA A 1 134 ? -23.274 183.634 13.301 1.00 21.93 ? 186 ALA A CA 1 ATOM 997 C C . ALA A 1 134 ? -22.068 184.375 13.865 1.00 22.73 ? 186 ALA A C 1 ATOM 998 O O . ALA A 1 134 ? -22.125 185.580 14.106 1.00 24.78 ? 186 ALA A O 1 ATOM 999 C CB . ALA A 1 134 ? -24.113 183.051 14.430 1.00 21.20 ? 186 ALA A CB 1 ATOM 1000 N N . SER A 1 135 ? -20.970 183.655 14.073 1.00 21.95 ? 187 SER A N 1 ATOM 1001 C CA . SER A 1 135 ? -19.733 184.297 14.509 1.00 25.63 ? 187 SER A CA 1 ATOM 1002 C C . SER A 1 135 ? -18.539 183.824 13.694 1.00 27.92 ? 187 SER A C 1 ATOM 1003 O O . SER A 1 135 ? -18.605 182.816 12.987 1.00 22.80 ? 187 SER A O 1 ATOM 1004 C CB . SER A 1 135 ? -19.481 184.037 15.994 1.00 32.04 ? 187 SER A CB 1 ATOM 1005 O OG . SER A 1 135 ? -19.455 182.649 16.275 1.00 38.71 ? 187 SER A OG 1 ATOM 1006 N N . ARG A 1 136 ? -17.454 184.584 13.801 1.00 29.40 ? 188 ARG A N 1 ATOM 1007 C CA . ARG A 1 136 ? -16.202 184.275 13.125 1.00 29.87 ? 188 ARG A CA 1 ATOM 1008 C C . ARG A 1 136 ? -15.245 183.546 14.070 1.00 25.04 ? 188 ARG A C 1 ATOM 1009 O O . ARG A 1 136 ? -15.453 183.511 15.286 1.00 22.41 ? 188 ARG A O 1 ATOM 1010 C CB . ARG A 1 136 ? -15.546 185.558 12.604 1.00 33.35 ? 188 ARG A CB 1 ATOM 1011 C CG . ARG A 1 136 ? -15.157 186.534 13.711 1.00 50.98 ? 188 ARG A CG 1 ATOM 1012 C CD . ARG A 1 136 ? -14.407 187.746 13.174 1.00 59.25 ? 188 ARG A CD 1 ATOM 1013 N NE . ARG A 1 136 ? -14.038 188.673 14.244 1.00 70.18 ? 188 ARG A NE 1 ATOM 1014 C CZ . ARG A 1 136 ? -14.817 189.653 14.698 1.00 70.97 ? 188 ARG A CZ 1 ATOM 1015 N NH1 . ARG A 1 136 ? -16.024 189.849 14.178 1.00 68.92 ? 188 ARG A NH1 1 ATOM 1016 N NH2 . ARG A 1 136 ? -14.390 190.442 15.675 1.00 72.04 ? 188 ARG A NH2 1 ATOM 1017 N N . ALA A 1 137 ? -14.198 182.963 13.496 1.00 23.18 ? 189 ALA A N 1 ATOM 1018 C CA . ALA A 1 137 ? -13.125 182.349 14.266 1.00 21.23 ? 189 ALA A CA 1 ATOM 1019 C C . ALA A 1 137 ? -11.878 182.320 13.397 1.00 22.93 ? 189 ALA A C 1 ATOM 1020 O O . ALA A 1 137 ? -11.975 182.184 12.176 1.00 25.36 ? 189 ALA A O 1 ATOM 1021 C CB . ALA A 1 137 ? -13.501 180.946 14.714 1.00 21.87 ? 189 ALA A CB 1 ATOM 1022 N N . ASP A 1 138 ? -10.716 182.449 14.026 1.00 22.62 ? 190 ASP A N 1 ATOM 1023 C CA . ASP A 1 138 ? -9.451 182.385 13.304 1.00 24.10 ? 190 ASP A CA 1 ATOM 1024 C C . ASP A 1 138 ? -9.116 180.936 12.969 1.00 22.77 ? 190 ASP A C 1 ATOM 1025 O O . ASP A 1 138 ? -9.437 180.039 13.747 1.00 19.71 ? 190 ASP A O 1 ATOM 1026 C CB . ASP A 1 138 ? -8.313 182.987 14.130 1.00 28.26 ? 190 ASP A CB 1 ATOM 1027 C CG . ASP A 1 138 ? -8.531 184.454 14.460 1.00 40.54 ? 190 ASP A CG 1 ATOM 1028 O OD1 . ASP A 1 138 ? -9.186 185.161 13.666 1.00 42.59 ? 190 ASP A OD1 1 ATOM 1029 O OD2 . ASP A 1 138 ? -8.032 184.898 15.517 1.00 50.59 ? 190 ASP A OD2 1 ATOM 1030 N N . PRO A 1 139 ? -8.469 180.706 11.814 1.00 21.30 ? 191 PRO A N 1 ATOM 1031 C CA . PRO A 1 139 ? -7.890 179.385 11.544 1.00 16.05 ? 191 PRO A CA 1 ATOM 1032 C C . PRO A 1 139 ? -7.043 178.912 12.720 1.00 21.35 ? 191 PRO A C 1 ATOM 1033 O O . PRO A 1 139 ? -6.223 179.677 13.237 1.00 22.00 ? 191 PRO A O 1 ATOM 1034 C CB . PRO A 1 139 ? -7.033 179.626 10.296 1.00 22.79 ? 191 PRO A CB 1 ATOM 1035 C CG . PRO A 1 139 ? -7.718 180.741 9.594 1.00 25.93 ? 191 PRO A CG 1 ATOM 1036 C CD . PRO A 1 139 ? -8.271 181.632 10.684 1.00 25.39 ? 191 PRO A CD 1 ATOM 1037 N N . GLY A 1 140 ? -7.257 177.666 13.132 1.00 17.61 ? 192 GLY A N 1 ATOM 1038 C CA . GLY A 1 140 ? -6.631 177.109 14.315 1.00 17.46 ? 192 GLY A CA 1 ATOM 1039 C C . GLY A 1 140 ? -7.629 176.874 15.437 1.00 15.88 ? 192 GLY A C 1 ATOM 1040 O O . GLY A 1 140 ? -7.440 175.989 16.262 1.00 15.47 ? 192 GLY A O 1 ATOM 1041 N N . ALA A 1 141 ? -8.700 177.663 15.465 1.00 16.35 ? 193 ALA A N 1 ATOM 1042 C CA . ALA A 1 141 ? -9.647 177.622 16.576 1.00 17.73 ? 193 ALA A CA 1 ATOM 1043 C C . ALA A 1 141 ? -10.296 176.257 16.773 1.00 14.32 ? 193 ALA A C 1 ATOM 1044 O O . ALA A 1 141 ? -10.644 175.897 17.893 1.00 16.71 ? 193 ALA A O 1 ATOM 1045 C CB . ALA A 1 141 ? -10.722 178.676 16.373 1.00 16.77 ? 193 ALA A CB 1 ATOM 1046 N N . ALA A 1 142 ? -10.458 175.493 15.694 1.00 13.67 ? 194 ALA A N 1 ATOM 1047 C CA . ALA A 1 142 ? -11.130 174.196 15.785 1.00 12.69 ? 194 ALA A CA 1 ATOM 1048 C C . ALA A 1 142 ? -10.170 173.028 16.028 1.00 12.88 ? 194 ALA A C 1 ATOM 1049 O O . ALA A 1 142 ? -10.605 171.893 16.247 1.00 14.03 ? 194 ALA A O 1 ATOM 1050 C CB . ALA A 1 142 ? -11.932 173.931 14.520 1.00 14.50 ? 194 ALA A CB 1 ATOM 1051 N N . GLU A 1 143 ? -8.869 173.304 15.982 1.00 13.68 ? 195 GLU A N 1 ATOM 1052 C CA . GLU A 1 143 ? -7.860 172.244 15.969 1.00 15.09 ? 195 GLU A CA 1 ATOM 1053 C C . GLU A 1 143 ? -7.518 171.725 17.364 1.00 13.30 ? 195 GLU A C 1 ATOM 1054 O O . GLU A 1 143 ? -7.792 172.381 18.366 1.00 14.15 ? 195 GLU A O 1 ATOM 1055 C CB . GLU A 1 143 ? -6.599 172.760 15.262 1.00 14.51 ? 195 GLU A CB 1 ATOM 1056 C CG . GLU A 1 143 ? -6.893 173.152 13.807 1.00 14.94 ? 195 GLU A CG 1 ATOM 1057 C CD . GLU A 1 143 ? -5.715 173.764 13.075 1.00 15.83 ? 195 GLU A CD 1 ATOM 1058 O OE1 . GLU A 1 143 ? -4.730 174.164 13.732 1.00 15.54 ? 195 GLU A OE1 1 ATOM 1059 O OE2 . GLU A 1 143 ? -5.784 173.849 11.831 1.00 14.44 ? 195 GLU A OE2 1 ATOM 1060 N N . VAL A 1 144 ? -6.943 170.528 17.428 1.00 14.15 ? 196 VAL A N 1 ATOM 1061 C CA . VAL A 1 144 ? -6.495 169.995 18.708 1.00 12.47 ? 196 VAL A CA 1 ATOM 1062 C C . VAL A 1 144 ? -5.541 170.989 19.364 1.00 15.96 ? 196 VAL A C 1 ATOM 1063 O O . VAL A 1 144 ? -4.813 171.711 18.678 1.00 15.35 ? 196 VAL A O 1 ATOM 1064 C CB . VAL A 1 144 ? -5.810 168.612 18.555 1.00 13.31 ? 196 VAL A CB 1 ATOM 1065 C CG1 . VAL A 1 144 ? -6.768 167.602 17.941 1.00 15.19 ? 196 VAL A CG1 1 ATOM 1066 C CG2 . VAL A 1 144 ? -4.540 168.712 17.729 1.00 16.87 ? 196 VAL A CG2 1 ATOM 1067 N N . ALA A 1 145 ? -5.555 171.035 20.693 1.00 13.64 ? 197 ALA A N 1 ATOM 1068 C CA . ALA A 1 145 ? -4.721 171.974 21.428 1.00 14.61 ? 197 ALA A CA 1 ATOM 1069 C C . ALA A 1 145 ? -3.265 171.780 21.023 1.00 11.80 ? 197 ALA A C 1 ATOM 1070 O O . ALA A 1 145 ? -2.832 170.650 20.809 1.00 13.02 ? 197 ALA A O 1 ATOM 1071 C CB . ALA A 1 145 ? -4.886 171.780 22.930 1.00 15.46 ? 197 ALA A CB 1 ATOM 1072 N N . LYS A 1 146 ? -2.519 172.873 20.909 1.00 13.92 ? 198 LYS A N 1 ATOM 1073 C CA . LYS A 1 146 ? -1.113 172.778 20.515 1.00 11.67 ? 198 LYS A CA 1 ATOM 1074 C C . LYS A 1 146 ? -0.348 171.818 21.431 1.00 13.03 ? 198 LYS A C 1 ATOM 1075 O O . LYS A 1 146 ? 0.527 171.078 20.975 1.00 12.77 ? 198 LYS A O 1 ATOM 1076 C CB . LYS A 1 146 ? -0.463 174.161 20.521 1.00 12.19 ? 198 LYS A CB 1 ATOM 1077 C CG . LYS A 1 146 ? 1.007 174.174 20.090 1.00 12.93 ? 198 LYS A CG 1 ATOM 1078 C CD . LYS A 1 146 ? 1.214 173.666 18.668 1.00 14.14 ? 198 LYS A CD 1 ATOM 1079 C CE . LYS A 1 146 ? 2.686 173.796 18.258 1.00 15.03 ? 198 LYS A CE 1 ATOM 1080 N NZ . LYS A 1 146 ? 2.948 173.389 16.855 1.00 15.27 ? 198 LYS A NZ 1 ATOM 1081 N N . SER A 1 147 ? -0.703 171.794 22.710 1.00 12.19 ? 199 SER A N 1 ATOM 1082 C CA . SER A 1 147 ? 0.006 170.963 23.671 1.00 11.99 ? 199 SER A CA 1 ATOM 1083 C C . SER A 1 147 ? -0.202 169.466 23.460 1.00 11.78 ? 199 SER A C 1 ATOM 1084 O O . SER A 1 147 ? 0.522 168.667 24.056 1.00 13.85 ? 199 SER A O 1 ATOM 1085 C CB . SER A 1 147 ? -0.402 171.349 25.095 1.00 14.10 ? 199 SER A CB 1 ATOM 1086 O OG . SER A 1 147 ? -1.805 171.205 25.272 1.00 14.53 ? 199 SER A OG 1 ATOM 1087 N N . ILE A 1 148 ? -1.171 169.078 22.622 1.00 11.83 ? 200 ILE A N 1 ATOM 1088 C CA . ILE A 1 148 ? -1.338 167.670 22.258 1.00 12.17 ? 200 ILE A CA 1 ATOM 1089 C C . ILE A 1 148 ? -1.198 167.423 20.750 1.00 12.61 ? 200 ILE A C 1 ATOM 1090 O O . ILE A 1 148 ? -1.538 166.344 20.269 1.00 14.26 ? 200 ILE A O 1 ATOM 1091 C CB . ILE A 1 148 ? -2.716 167.104 22.726 1.00 14.10 ? 200 ILE A CB 1 ATOM 1092 C CG1 . ILE A 1 148 ? -3.882 167.682 21.915 1.00 14.98 ? 200 ILE A CG1 1 ATOM 1093 C CG2 . ILE A 1 148 ? -2.925 167.375 24.214 1.00 17.62 ? 200 ILE A CG2 1 ATOM 1094 C CD1 . ILE A 1 148 ? -5.137 166.820 21.979 1.00 21.10 ? 200 ILE A CD1 1 ATOM 1095 N N . GLU A 1 149 ? -0.695 168.408 20.013 1.00 11.11 ? 201 GLU A N 1 ATOM 1096 C CA . GLU A 1 149 ? -0.518 168.271 18.564 1.00 13.05 ? 201 GLU A CA 1 ATOM 1097 C C . GLU A 1 149 ? 0.276 167.018 18.213 1.00 12.63 ? 201 GLU A C 1 ATOM 1098 O O . GLU A 1 149 ? 1.276 166.712 18.862 1.00 13.98 ? 201 GLU A O 1 ATOM 1099 C CB . GLU A 1 149 ? 0.200 169.488 17.980 1.00 12.32 ? 201 GLU A CB 1 ATOM 1100 C CG . GLU A 1 149 ? 0.343 169.427 16.453 1.00 13.50 ? 201 GLU A CG 1 ATOM 1101 C CD . GLU A 1 149 ? 1.278 170.477 15.874 1.00 14.51 ? 201 GLU A CD 1 ATOM 1102 O OE1 . GLU A 1 149 ? 2.308 170.802 16.509 1.00 14.81 ? 201 GLU A OE1 1 ATOM 1103 O OE2 . GLU A 1 149 ? 0.995 170.965 14.763 1.00 13.56 ? 201 GLU A OE2 1 ATOM 1104 N N . GLY A 1 150 ? -0.168 166.314 17.173 1.00 12.16 ? 202 GLY A N 1 ATOM 1105 C CA . GLY A 1 150 ? 0.580 165.214 16.598 1.00 11.99 ? 202 GLY A CA 1 ATOM 1106 C C . GLY A 1 150 ? 1.001 165.544 15.172 1.00 9.54 ? 202 GLY A C 1 ATOM 1107 O O . GLY A 1 150 ? 1.231 166.710 14.830 1.00 11.78 ? 202 GLY A O 1 ATOM 1108 N N . PHE A 1 151 ? 1.066 164.514 14.334 1.00 10.30 ? 203 PHE A N 1 ATOM 1109 C CA . PHE A 1 151 ? 1.511 164.664 12.947 1.00 10.03 ? 203 PHE A CA 1 ATOM 1110 C C . PHE A 1 151 ? 0.457 164.276 11.918 1.00 11.72 ? 203 PHE A C 1 ATOM 1111 O O . PHE A 1 151 ? 0.712 164.369 10.720 1.00 12.80 ? 203 PHE A O 1 ATOM 1112 C CB . PHE A 1 151 ? 2.760 163.812 12.711 1.00 13.09 ? 203 PHE A CB 1 ATOM 1113 C CG . PHE A 1 151 ? 4.022 164.600 12.579 1.00 11.67 ? 203 PHE A CG 1 ATOM 1114 C CD1 . PHE A 1 151 ? 4.400 165.493 13.562 1.00 12.05 ? 203 PHE A CD1 1 ATOM 1115 C CD2 . PHE A 1 151 ? 4.850 164.414 11.486 1.00 13.26 ? 203 PHE A CD2 1 ATOM 1116 C CE1 . PHE A 1 151 ? 5.571 166.210 13.449 1.00 14.21 ? 203 PHE A CE1 1 ATOM 1117 C CE2 . PHE A 1 151 ? 6.028 165.121 11.372 1.00 14.35 ? 203 PHE A CE2 1 ATOM 1118 C CZ . PHE A 1 151 ? 6.386 166.018 12.354 1.00 12.51 ? 203 PHE A CZ 1 ATOM 1119 N N . ALA A 1 152 ? -0.719 163.837 12.363 1.00 10.78 ? 204 ALA A N 1 ATOM 1120 C CA . ALA A 1 152 ? -1.707 163.313 11.426 1.00 11.72 ? 204 ALA A CA 1 ATOM 1121 C C . ALA A 1 152 ? -2.454 164.423 10.706 1.00 11.94 ? 204 ALA A C 1 ATOM 1122 O O . ALA A 1 152 ? -2.813 165.432 11.293 1.00 11.24 ? 204 ALA A O 1 ATOM 1123 C CB . ALA A 1 152 ? -2.694 162.414 12.145 1.00 13.32 ? 204 ALA A CB 1 ATOM 1124 N N . MET A 1 153 ? -2.706 164.218 9.420 1.00 11.03 ? 205 MET A N 1 ATOM 1125 C CA . MET A 1 153 ? -3.455 165.196 8.644 1.00 10.43 ? 205 MET A CA 1 ATOM 1126 C C . MET A 1 153 ? -4.899 165.258 9.140 1.00 12.39 ? 205 MET A C 1 ATOM 1127 O O . MET A 1 153 ? -5.417 164.289 9.698 1.00 12.15 ? 205 MET A O 1 ATOM 1128 C CB . MET A 1 153 ? -3.399 164.847 7.155 1.00 10.72 ? 205 MET A CB 1 ATOM 1129 C CG . MET A 1 153 ? -4.016 165.882 6.231 1.00 11.10 ? 205 MET A CG 1 ATOM 1130 S SD . MET A 1 153 ? -3.323 167.518 6.528 1.00 12.59 ? 205 MET A SD 1 ATOM 1131 C CE . MET A 1 153 ? -4.177 168.460 5.260 1.00 13.91 ? 205 MET A CE 1 ATOM 1132 N N . TYR A 1 154 ? -5.530 166.411 8.934 1.00 11.29 ? 206 TYR A N 1 ATOM 1133 C CA . TYR A 1 154 ? -6.945 166.591 9.250 1.00 11.86 ? 206 TYR A CA 1 ATOM 1134 C C . TYR A 1 154 ? -7.770 165.470 8.645 1.00 10.97 ? 206 TYR A C 1 ATOM 1135 O O . TYR A 1 154 ? -7.451 164.949 7.578 1.00 13.71 ? 206 TYR A O 1 ATOM 1136 C CB . TYR A 1 154 ? -7.431 167.954 8.744 1.00 13.60 ? 206 TYR A CB 1 ATOM 1137 C CG . TYR A 1 154 ? -6.577 169.103 9.230 1.00 11.59 ? 206 TYR A CG 1 ATOM 1138 C CD1 . TYR A 1 154 ? -6.571 169.469 10.571 1.00 13.04 ? 206 TYR A CD1 1 ATOM 1139 C CD2 . TYR A 1 154 ? -5.776 169.814 8.354 1.00 13.13 ? 206 TYR A CD2 1 ATOM 1140 C CE1 . TYR A 1 154 ? -5.785 170.509 11.028 1.00 12.07 ? 206 TYR A CE1 1 ATOM 1141 C CE2 . TYR A 1 154 ? -4.991 170.867 8.798 1.00 14.58 ? 206 TYR A CE2 1 ATOM 1142 C CZ . TYR A 1 154 ? -4.997 171.208 10.134 1.00 11.74 ? 206 TYR A CZ 1 ATOM 1143 O OH . TYR A 1 154 ? -4.214 172.258 10.582 1.00 14.07 ? 206 TYR A OH 1 ATOM 1144 N N . ALA A 1 155 ? -8.839 165.095 9.339 1.00 13.40 ? 207 ALA A N 1 ATOM 1145 C CA . ALA A 1 155 ? -9.639 163.952 8.921 1.00 12.69 ? 207 ALA A CA 1 ATOM 1146 C C . ALA A 1 155 ? -10.303 164.158 7.566 1.00 13.71 ? 207 ALA A C 1 ATOM 1147 O O . ALA A 1 155 ? -10.478 163.210 6.802 1.00 14.40 ? 207 ALA A O 1 ATOM 1148 C CB . ALA A 1 155 ? -10.694 163.659 9.957 1.00 14.33 ? 207 ALA A CB 1 ATOM 1149 N N . GLY A 1 156 ? -10.695 165.389 7.285 1.00 13.30 ? 208 GLY A N 1 ATOM 1150 C CA . GLY A 1 156 ? -11.386 165.698 6.051 1.00 13.62 ? 208 GLY A CA 1 ATOM 1151 C C . GLY A 1 156 ? -11.649 167.183 5.959 1.00 13.43 ? 208 GLY A C 1 ATOM 1152 O O . GLY A 1 156 ? -11.306 167.947 6.868 1.00 15.18 ? 208 GLY A O 1 ATOM 1153 N N . TYR A 1 157 ? -12.253 167.600 4.853 1.00 14.60 ? 209 TYR A N 1 ATOM 1154 C CA . TYR A 1 157 ? -12.540 169.010 4.613 1.00 14.70 ? 209 TYR A CA 1 ATOM 1155 C C . TYR A 1 157 ? -13.687 169.097 3.605 1.00 16.35 ? 209 TYR A C 1 ATOM 1156 O O . TYR A 1 157 ? -13.642 168.450 2.559 1.00 16.41 ? 209 TYR A O 1 ATOM 1157 C CB . TYR A 1 157 ? -11.292 169.750 4.109 1.00 14.49 ? 209 TYR A CB 1 ATOM 1158 C CG . TYR A 1 157 ? -11.565 171.175 3.701 1.00 16.43 ? 209 TYR A CG 1 ATOM 1159 C CD1 . TYR A 1 157 ? -11.932 172.133 4.639 1.00 17.65 ? 209 TYR A CD1 1 ATOM 1160 C CD2 . TYR A 1 157 ? -11.464 171.564 2.374 1.00 19.10 ? 209 TYR A CD2 1 ATOM 1161 C CE1 . TYR A 1 157 ? -12.194 173.438 4.255 1.00 19.26 ? 209 TYR A CE1 1 ATOM 1162 C CE2 . TYR A 1 157 ? -11.717 172.862 1.988 1.00 16.63 ? 209 TYR A CE2 1 ATOM 1163 C CZ . TYR A 1 157 ? -12.087 173.789 2.922 1.00 18.13 ? 209 TYR A CZ 1 ATOM 1164 O OH . TYR A 1 157 ? -12.345 175.080 2.514 1.00 22.70 ? 209 TYR A OH 1 ATOM 1165 N N . LEU A 1 158 ? -14.714 169.880 3.951 1.00 14.78 ? 210 LEU A N 1 ATOM 1166 C CA . LEU A 1 158 ? -15.988 169.951 3.214 1.00 16.29 ? 210 LEU A CA 1 ATOM 1167 C C . LEU A 1 158 ? -16.684 168.591 3.262 1.00 17.51 ? 210 LEU A C 1 ATOM 1168 O O . LEU A 1 158 ? -16.158 167.639 3.826 1.00 18.41 ? 210 LEU A O 1 ATOM 1169 C CB . LEU A 1 158 ? -15.775 170.414 1.764 1.00 16.55 ? 210 LEU A CB 1 ATOM 1170 C CG . LEU A 1 158 ? -15.008 171.731 1.627 1.00 15.49 ? 210 LEU A CG 1 ATOM 1171 C CD1 . LEU A 1 158 ? -14.785 172.094 0.167 1.00 16.72 ? 210 LEU A CD1 1 ATOM 1172 C CD2 . LEU A 1 158 ? -15.716 172.859 2.358 1.00 18.86 ? 210 LEU A CD2 1 ATOM 1173 N N . THR A 1 159 ? -17.886 168.489 2.704 1.00 15.98 ? 211 THR A N 1 ATOM 1174 C CA . THR A 1 159 ? -18.625 167.231 2.830 1.00 14.32 ? 211 THR A CA 1 ATOM 1175 C C . THR A 1 159 ? -17.967 166.092 2.059 1.00 14.22 ? 211 THR A C 1 ATOM 1176 O O . THR A 1 159 ? -18.078 164.930 2.447 1.00 14.55 ? 211 THR A O 1 ATOM 1177 C CB . THR A 1 159 ? -20.094 167.366 2.351 1.00 16.49 ? 211 THR A CB 1 ATOM 1178 O OG1 . THR A 1 159 ? -20.131 167.900 1.022 1.00 19.66 ? 211 THR A OG1 1 ATOM 1179 C CG2 . THR A 1 159 ? -20.874 168.265 3.284 1.00 16.84 ? 211 THR A CG2 1 ATOM 1180 N N . HIS A 1 160 ? -17.291 166.422 0.966 1.00 16.03 ? 212 HIS A N 1 ATOM 1181 C CA . HIS A 1 160 ? -16.684 165.406 0.116 1.00 16.90 ? 212 HIS A CA 1 ATOM 1182 C C . HIS A 1 160 ? -15.682 166.053 -0.828 1.00 14.40 ? 212 HIS A C 1 ATOM 1183 O O . HIS A 1 160 ? -15.659 167.274 -0.992 1.00 15.56 ? 212 HIS A O 1 ATOM 1184 C CB . HIS A 1 160 ? -17.761 164.648 -0.676 1.00 18.55 ? 212 HIS A CB 1 ATOM 1185 C CG . HIS A 1 160 ? -18.532 165.518 -1.616 1.00 18.95 ? 212 HIS A CG 1 ATOM 1186 N ND1 . HIS A 1 160 ? -19.519 166.380 -1.189 1.00 20.06 ? 212 HIS A ND1 1 ATOM 1187 C CD2 . HIS A 1 160 ? -18.457 165.666 -2.961 1.00 20.19 ? 212 HIS A CD2 1 ATOM 1188 C CE1 . HIS A 1 160 ? -20.017 167.025 -2.231 1.00 21.88 ? 212 HIS A CE1 1 ATOM 1189 N NE2 . HIS A 1 160 ? -19.390 166.611 -3.318 1.00 19.69 ? 212 HIS A NE2 1 ATOM 1190 N N . CYS A 1 161 ? -14.844 165.213 -1.423 1.00 14.14 ? 213 CYS A N 1 ATOM 1191 C CA . CYS A 1 161 ? -13.814 165.643 -2.346 1.00 17.30 ? 213 CYS A CA 1 ATOM 1192 C C . CYS A 1 161 ? -13.904 164.818 -3.633 1.00 15.81 ? 213 CYS A C 1 ATOM 1193 O O . CYS A 1 161 ? -13.944 163.592 -3.567 1.00 17.97 ? 213 CYS A O 1 ATOM 1194 C CB . CYS A 1 161 ? -12.435 165.482 -1.708 1.00 19.99 ? 213 CYS A CB 1 ATOM 1195 S SG . CYS A 1 161 ? -11.110 165.958 -2.827 1.00 17.89 ? 213 CYS A SG 1 ATOM 1196 N N . PRO A 1 162 ? -13.945 165.478 -4.804 1.00 16.17 ? 214 PRO A N 1 ATOM 1197 C CA . PRO A 1 162 ? -13.947 166.927 -5.045 1.00 17.86 ? 214 PRO A CA 1 ATOM 1198 C C . PRO A 1 162 ? -15.297 167.536 -4.687 1.00 18.43 ? 214 PRO A C 1 ATOM 1199 O O . PRO A 1 162 ? -16.321 167.001 -5.117 1.00 18.96 ? 214 PRO A O 1 ATOM 1200 C CB . PRO A 1 162 ? -13.672 167.035 -6.548 1.00 18.92 ? 214 PRO A CB 1 ATOM 1201 C CG . PRO A 1 162 ? -14.244 165.777 -7.108 1.00 19.02 ? 214 PRO A CG 1 ATOM 1202 C CD . PRO A 1 162 ? -13.983 164.719 -6.069 1.00 21.60 ? 214 PRO A CD 1 ATOM 1203 N N . TYR A 1 163 ? -15.312 168.617 -3.916 1.00 16.81 ? 215 TYR A N 1 ATOM 1204 C CA . TYR A 1 163 ? -16.586 169.154 -3.439 1.00 15.67 ? 215 TYR A CA 1 ATOM 1205 C C . TYR A 1 163 ? -17.429 169.721 -4.586 1.00 19.07 ? 215 TYR A C 1 ATOM 1206 O O . TYR A 1 163 ? -18.658 169.625 -4.555 1.00 19.82 ? 215 TYR A O 1 ATOM 1207 C CB . TYR A 1 163 ? -16.380 170.235 -2.373 1.00 16.05 ? 215 TYR A CB 1 ATOM 1208 C CG . TYR A 1 163 ? -17.691 170.898 -1.991 1.00 16.75 ? 215 TYR A CG 1 ATOM 1209 C CD1 . TYR A 1 163 ? -18.579 170.275 -1.122 1.00 16.56 ? 215 TYR A CD1 1 ATOM 1210 C CD2 . TYR A 1 163 ? -18.057 172.122 -2.535 1.00 19.07 ? 215 TYR A CD2 1 ATOM 1211 C CE1 . TYR A 1 163 ? -19.788 170.861 -0.790 1.00 18.37 ? 215 TYR A CE1 1 ATOM 1212 C CE2 . TYR A 1 163 ? -19.261 172.718 -2.206 1.00 17.43 ? 215 TYR A CE2 1 ATOM 1213 C CZ . TYR A 1 163 ? -20.121 172.085 -1.337 1.00 18.75 ? 215 TYR A CZ 1 ATOM 1214 O OH . TYR A 1 163 ? -21.323 172.686 -1.027 1.00 19.14 ? 215 TYR A OH 1 ATOM 1215 N N . ASN A 1 164 ? -16.784 170.333 -5.575 1.00 17.65 ? 216 ASN A N 1 ATOM 1216 C CA . ASN A 1 164 ? -17.501 170.798 -6.762 1.00 18.93 ? 216 ASN A CA 1 ATOM 1217 C C . ASN A 1 164 ? -16.729 170.440 -8.025 1.00 22.74 ? 216 ASN A C 1 ATOM 1218 O O . ASN A 1 164 ? -15.591 169.984 -7.953 1.00 18.53 ? 216 ASN A O 1 ATOM 1219 C CB . ASN A 1 164 ? -17.770 172.309 -6.682 1.00 22.14 ? 216 ASN A CB 1 ATOM 1220 C CG . ASN A 1 164 ? -16.506 173.150 -6.743 1.00 19.38 ? 216 ASN A CG 1 ATOM 1221 O OD1 . ASN A 1 164 ? -15.609 172.898 -7.543 1.00 18.96 ? 216 ASN A OD1 1 ATOM 1222 N ND2 . ASN A 1 164 ? -16.446 174.182 -5.908 1.00 18.96 ? 216 ASN A ND2 1 ATOM 1223 N N . VAL A 1 165 ? -17.341 170.636 -9.187 1.00 21.34 ? 217 VAL A N 1 ATOM 1224 C CA . VAL A 1 165 ? -16.731 170.157 -10.421 1.00 24.33 ? 217 VAL A CA 1 ATOM 1225 C C . VAL A 1 165 ? -15.514 170.984 -10.814 1.00 21.44 ? 217 VAL A C 1 ATOM 1226 O O . VAL A 1 165 ? -14.680 170.518 -11.591 1.00 21.07 ? 217 VAL A O 1 ATOM 1227 C CB . VAL A 1 165 ? -17.741 170.146 -11.591 1.00 27.96 ? 217 VAL A CB 1 ATOM 1228 C CG1 . VAL A 1 165 ? -18.862 169.160 -11.301 1.00 30.87 ? 217 VAL A CG1 1 ATOM 1229 C CG2 . VAL A 1 165 ? -18.291 171.526 -11.845 1.00 26.80 ? 217 VAL A CG2 1 ATOM 1230 N N . ASN A 1 166 ? -15.395 172.193 -10.269 1.00 19.58 ? 218 ASN A N 1 ATOM 1231 C CA . ASN A 1 166 ? -14.238 173.033 -10.545 1.00 21.02 ? 218 ASN A CA 1 ATOM 1232 C C . ASN A 1 166 ? -12.987 172.498 -9.857 1.00 19.39 ? 218 ASN A C 1 ATOM 1233 O O . ASN A 1 166 ? -11.896 172.571 -10.413 1.00 18.64 ? 218 ASN A O 1 ATOM 1234 C CB . ASN A 1 166 ? -14.509 174.473 -10.119 1.00 21.88 ? 218 ASN A CB 1 ATOM 1235 C CG . ASN A 1 166 ? -15.599 175.120 -10.951 1.00 28.61 ? 218 ASN A CG 1 ATOM 1236 O OD1 . ASN A 1 166 ? -16.152 174.497 -11.856 1.00 29.07 ? 218 ASN A OD1 1 ATOM 1237 N ND2 . ASN A 1 166 ? -15.919 176.363 -10.642 1.00 29.12 ? 218 ASN A ND2 1 ATOM 1238 N N . VAL A 1 167 ? -13.150 171.964 -8.651 1.00 18.28 ? 219 VAL A N 1 ATOM 1239 C CA . VAL A 1 167 ? -12.046 171.291 -7.970 1.00 19.17 ? 219 VAL A CA 1 ATOM 1240 C C . VAL A 1 167 ? -11.530 170.185 -8.888 1.00 17.71 ? 219 VAL A C 1 ATOM 1241 O O . VAL A 1 167 ? -10.329 170.085 -9.147 1.00 17.35 ? 219 VAL A O 1 ATOM 1242 C CB . VAL A 1 167 ? -12.476 170.689 -6.604 1.00 17.58 ? 219 VAL A CB 1 ATOM 1243 C CG1 . VAL A 1 167 ? -11.359 169.841 -5.991 1.00 16.69 ? 219 VAL A CG1 1 ATOM 1244 C CG2 . VAL A 1 167 ? -12.895 171.777 -5.631 1.00 16.82 ? 219 VAL A CG2 1 ATOM 1245 N N . TYR A 1 168 ? -12.448 169.372 -9.404 1.00 17.49 ? 220 TYR A N 1 ATOM 1246 C CA . TYR A 1 168 ? -12.068 168.252 -10.250 1.00 16.83 ? 220 TYR A CA 1 ATOM 1247 C C . TYR A 1 168 ? -11.484 168.690 -11.585 1.00 20.25 ? 220 TYR A C 1 ATOM 1248 O O . TYR A 1 168 ? -10.452 168.177 -12.008 1.00 19.12 ? 220 TYR A O 1 ATOM 1249 C CB . TYR A 1 168 ? -13.262 167.326 -10.506 1.00 19.42 ? 220 TYR A CB 1 ATOM 1250 C CG . TYR A 1 168 ? -12.833 166.056 -11.196 1.00 21.40 ? 220 TYR A CG 1 ATOM 1251 C CD1 . TYR A 1 168 ? -12.034 165.135 -10.538 1.00 22.40 ? 220 TYR A CD1 1 ATOM 1252 C CD2 . TYR A 1 168 ? -13.193 165.792 -12.512 1.00 27.21 ? 220 TYR A CD2 1 ATOM 1253 C CE1 . TYR A 1 168 ? -11.617 163.978 -11.156 1.00 24.93 ? 220 TYR A CE1 1 ATOM 1254 C CE2 . TYR A 1 168 ? -12.783 164.628 -13.141 1.00 28.45 ? 220 TYR A CE2 1 ATOM 1255 C CZ . TYR A 1 168 ? -11.990 163.726 -12.456 1.00 27.72 ? 220 TYR A CZ 1 ATOM 1256 O OH . TYR A 1 168 ? -11.562 162.565 -13.061 1.00 27.60 ? 220 TYR A OH 1 ATOM 1257 N N . ARG A 1 169 ? -12.123 169.644 -12.253 1.00 20.32 ? 221 ARG A N 1 ATOM 1258 C CA . ARG A 1 169 ? -11.746 169.938 -13.630 1.00 21.28 ? 221 ARG A CA 1 ATOM 1259 C C . ARG A 1 169 ? -10.625 170.978 -13.755 1.00 20.04 ? 221 ARG A C 1 ATOM 1260 O O . ARG A 1 169 ? -9.864 170.940 -14.725 1.00 24.94 ? 221 ARG A O 1 ATOM 1261 C CB . ARG A 1 169 ? -12.987 170.373 -14.415 1.00 24.00 ? 221 ARG A CB 1 ATOM 1262 C CG . ARG A 1 169 ? -13.880 169.184 -14.773 1.00 27.18 ? 221 ARG A CG 1 ATOM 1263 C CD . ARG A 1 169 ? -15.307 169.548 -15.176 1.00 42.42 ? 221 ARG A CD 1 ATOM 1264 N NE . ARG A 1 169 ? -15.493 170.948 -15.543 1.00 53.55 ? 221 ARG A NE 1 ATOM 1265 C CZ . ARG A 1 169 ? -16.653 171.457 -15.950 1.00 59.68 ? 221 ARG A CZ 1 ATOM 1266 N NH1 . ARG A 1 169 ? -16.741 172.744 -16.263 1.00 41.40 ? 221 ARG A NH1 1 ATOM 1267 N NH2 . ARG A 1 169 ? -17.725 170.676 -16.044 1.00 40.51 ? 221 ARG A NH2 1 ATOM 1268 N N . GLN A 1 170 ? -10.497 171.875 -12.776 1.00 18.82 ? 222 GLN A N 1 ATOM 1269 C CA . GLN A 1 170 ? -9.500 172.947 -12.838 1.00 18.90 ? 222 GLN A CA 1 ATOM 1270 C C . GLN A 1 170 ? -8.235 172.629 -12.044 1.00 17.45 ? 222 GLN A C 1 ATOM 1271 O O . GLN A 1 170 ? -7.169 173.178 -12.336 1.00 22.22 ? 222 GLN A O 1 ATOM 1272 C CB . GLN A 1 170 ? -10.052 174.273 -12.303 1.00 21.73 ? 222 GLN A CB 1 ATOM 1273 C CG . GLN A 1 170 ? -11.533 174.511 -12.494 1.00 41.78 ? 222 GLN A CG 1 ATOM 1274 C CD . GLN A 1 170 ? -11.826 175.345 -13.702 1.00 46.08 ? 222 GLN A CD 1 ATOM 1275 O OE1 . GLN A 1 170 ? -11.270 175.121 -14.779 1.00 49.96 ? 222 GLN A OE1 1 ATOM 1276 N NE2 . GLN A 1 170 ? -12.704 176.326 -13.534 1.00 46.34 ? 222 GLN A NE2 1 ATOM 1277 N N . ASP A 1 171 ? -8.362 171.794 -11.014 1.00 17.26 ? 223 ASP A N 1 ATOM 1278 C CA . ASP A 1 171 ? -7.208 171.450 -10.178 1.00 17.11 ? 223 ASP A CA 1 ATOM 1279 C C . ASP A 1 171 ? -6.747 170.016 -10.377 1.00 16.91 ? 223 ASP A C 1 ATOM 1280 O O . ASP A 1 171 ? -5.566 169.782 -10.590 1.00 18.36 ? 223 ASP A O 1 ATOM 1281 C CB . ASP A 1 171 ? -7.514 171.684 -8.691 1.00 18.47 ? 223 ASP A CB 1 ATOM 1282 C CG . ASP A 1 171 ? -7.330 173.136 -8.268 1.00 19.22 ? 223 ASP A CG 1 ATOM 1283 O OD1 . ASP A 1 171 ? -6.780 173.941 -9.049 1.00 18.74 ? 223 ASP A OD1 1 ATOM 1284 O OD2 . ASP A 1 171 ? -7.722 173.474 -7.130 1.00 19.03 ? 223 ASP A OD2 1 ATOM 1285 N N . MET A 1 172 ? -7.657 169.055 -10.302 1.00 16.71 ? 224 MET A N 1 ATOM 1286 C CA . MET A 1 172 ? -7.259 167.652 -10.362 1.00 15.37 ? 224 MET A CA 1 ATOM 1287 C C . MET A 1 172 ? -6.907 167.169 -11.771 1.00 19.31 ? 224 MET A C 1 ATOM 1288 O O . MET A 1 172 ? -5.777 166.749 -12.004 1.00 19.26 ? 224 MET A O 1 ATOM 1289 C CB . MET A 1 172 ? -8.355 166.781 -9.764 1.00 17.03 ? 224 MET A CB 1 ATOM 1290 C CG . MET A 1 172 ? -8.459 166.917 -8.255 1.00 17.63 ? 224 MET A CG 1 ATOM 1291 S SD . MET A 1 172 ? -9.890 166.047 -7.602 1.00 22.87 ? 224 MET A SD 1 ATOM 1292 C CE . MET A 1 172 ? -9.516 165.992 -5.855 1.00 25.32 ? 224 MET A CE 1 ATOM 1293 N N . VAL A 1 173 ? -7.844 167.233 -12.716 1.00 16.89 ? 225 VAL A N 1 ATOM 1294 C CA . VAL A 1 173 ? -7.617 166.574 -14.007 1.00 18.30 ? 225 VAL A CA 1 ATOM 1295 C C . VAL A 1 173 ? -6.469 167.182 -14.808 1.00 20.13 ? 225 VAL A C 1 ATOM 1296 O O . VAL A 1 173 ? -5.832 166.487 -15.601 1.00 24.21 ? 225 VAL A O 1 ATOM 1297 C CB . VAL A 1 173 ? -8.890 166.586 -14.894 1.00 24.38 ? 225 VAL A CB 1 ATOM 1298 C CG1 . VAL A 1 173 ? -9.992 165.804 -14.233 1.00 28.96 ? 225 VAL A CG1 1 ATOM 1299 C CG2 . VAL A 1 173 ? -9.316 167.992 -15.207 1.00 30.78 ? 225 VAL A CG2 1 ATOM 1300 N N . THR A 1 174 ? -6.201 168.466 -14.602 1.00 19.04 ? 226 THR A N 1 ATOM 1301 C CA . THR A 1 174 ? -5.128 169.149 -15.318 1.00 19.60 ? 226 THR A CA 1 ATOM 1302 C C . THR A 1 174 ? -3.803 169.153 -14.535 1.00 21.18 ? 226 THR A C 1 ATOM 1303 O O . THR A 1 174 ? -2.850 169.839 -14.913 1.00 23.10 ? 226 THR A O 1 ATOM 1304 C CB . THR A 1 174 ? -5.525 170.597 -15.654 1.00 24.74 ? 226 THR A CB 1 ATOM 1305 O OG1 . THR A 1 174 ? -5.899 171.292 -14.458 1.00 21.51 ? 226 THR A OG1 1 ATOM 1306 C CG2 . THR A 1 174 ? -6.701 170.615 -16.628 1.00 24.65 ? 226 THR A CG2 1 ATOM 1307 N N . ASP A 1 175 ? -3.758 168.380 -13.452 1.00 18.36 ? 227 ASP A N 1 ATOM 1308 C CA . ASP A 1 175 ? -2.535 168.154 -12.680 1.00 18.07 ? 227 ASP A CA 1 ATOM 1309 C C . ASP A 1 175 ? -1.790 166.981 -13.297 1.00 16.89 ? 227 ASP A C 1 ATOM 1310 O O . ASP A 1 175 ? -2.341 165.886 -13.398 1.00 17.03 ? 227 ASP A O 1 ATOM 1311 C CB . ASP A 1 175 ? -2.897 167.874 -11.213 1.00 17.13 ? 227 ASP A CB 1 ATOM 1312 C CG . ASP A 1 175 ? -1.685 167.809 -10.285 1.00 19.35 ? 227 ASP A CG 1 ATOM 1313 O OD1 . ASP A 1 175 ? -0.564 167.463 -10.728 1.00 17.14 ? 227 ASP A OD1 1 ATOM 1314 O OD2 . ASP A 1 175 ? -1.880 168.089 -9.080 1.00 16.61 ? 227 ASP A OD2 1 ATOM 1315 N N . LYS A 1 176 ? -0.536 167.192 -13.687 1.00 15.86 ? 228 LYS A N 1 ATOM 1316 C CA . LYS A 1 176 ? 0.211 166.156 -14.391 1.00 18.50 ? 228 LYS A CA 1 ATOM 1317 C C . LYS A 1 176 ? 0.520 164.940 -13.511 1.00 18.73 ? 228 LYS A C 1 ATOM 1318 O O . LYS A 1 176 ? 0.878 163.880 -14.027 1.00 17.67 ? 228 LYS A O 1 ATOM 1319 C CB . LYS A 1 176 ? 1.500 166.749 -14.966 1.00 20.95 ? 228 LYS A CB 1 ATOM 1320 C CG . LYS A 1 176 ? 1.224 167.852 -15.980 1.00 28.49 ? 228 LYS A CG 1 ATOM 1321 C CD . LYS A 1 176 ? 2.461 168.245 -16.770 1.00 34.83 ? 228 LYS A CD 1 ATOM 1322 C CE . LYS A 1 176 ? 2.110 169.283 -17.826 1.00 38.71 ? 228 LYS A CE 1 ATOM 1323 N NZ . LYS A 1 176 ? 3.242 169.566 -18.753 1.00 51.92 ? 228 LYS A NZ 1 ATOM 1324 N N . GLU A 1 177 ? 0.342 165.073 -12.197 1.00 16.14 ? 229 GLU A N 1 ATOM 1325 C CA . GLU A 1 177 ? 0.523 163.935 -11.293 1.00 15.67 ? 229 GLU A CA 1 ATOM 1326 C C . GLU A 1 177 ? -0.778 163.188 -11.001 1.00 15.50 ? 229 GLU A C 1 ATOM 1327 O O . GLU A 1 177 ? -0.763 162.114 -10.402 1.00 15.72 ? 229 GLU A O 1 ATOM 1328 C CB . GLU A 1 177 ? 1.153 164.394 -9.972 1.00 14.45 ? 229 GLU A CB 1 ATOM 1329 C CG . GLU A 1 177 ? 2.609 164.788 -10.122 1.00 14.68 ? 229 GLU A CG 1 ATOM 1330 C CD . GLU A 1 177 ? 3.374 164.685 -8.823 1.00 15.35 ? 229 GLU A CD 1 ATOM 1331 O OE1 . GLU A 1 177 ? 3.125 165.511 -7.920 1.00 15.18 ? 229 GLU A OE1 1 ATOM 1332 O OE2 . GLU A 1 177 ? 4.221 163.774 -8.707 1.00 15.25 ? 229 GLU A OE2 1 ATOM 1333 N N . PHE A 1 178 ? -1.904 163.764 -11.409 1.00 17.89 ? 230 PHE A N 1 ATOM 1334 C CA . PHE A 1 178 ? -3.201 163.153 -11.167 1.00 16.15 ? 230 PHE A CA 1 ATOM 1335 C C . PHE A 1 178 ? -3.557 162.219 -12.313 1.00 18.91 ? 230 PHE A C 1 ATOM 1336 O O . PHE A 1 178 ? -3.229 162.497 -13.462 1.00 21.44 ? 230 PHE A O 1 ATOM 1337 C CB . PHE A 1 178 ? -4.269 164.232 -11.013 1.00 16.68 ? 230 PHE A CB 1 ATOM 1338 C CG . PHE A 1 178 ? -5.616 163.710 -10.576 1.00 18.33 ? 230 PHE A CG 1 ATOM 1339 C CD1 . PHE A 1 178 ? -5.909 163.568 -9.233 1.00 17.78 ? 230 PHE A CD1 1 ATOM 1340 C CD2 . PHE A 1 178 ? -6.593 163.387 -11.508 1.00 17.75 ? 230 PHE A CD2 1 ATOM 1341 C CE1 . PHE A 1 178 ? -7.139 163.102 -8.815 1.00 19.42 ? 230 PHE A CE1 1 ATOM 1342 C CE2 . PHE A 1 178 ? -7.833 162.910 -11.099 1.00 21.03 ? 230 PHE A CE2 1 ATOM 1343 C CZ . PHE A 1 178 ? -8.107 162.771 -9.753 1.00 21.11 ? 230 PHE A CZ 1 ATOM 1344 N N . ASP A 1 179 ? -4.208 161.106 -11.991 1.00 18.46 ? 231 ASP A N 1 ATOM 1345 C CA . ASP A 1 179 ? -4.731 160.203 -13.008 1.00 20.56 ? 231 ASP A CA 1 ATOM 1346 C C . ASP A 1 179 ? -6.107 159.720 -12.569 1.00 20.95 ? 231 ASP A C 1 ATOM 1347 O O . ASP A 1 179 ? -6.256 159.198 -11.475 1.00 19.36 ? 231 ASP A O 1 ATOM 1348 C CB . ASP A 1 179 ? -3.790 159.021 -13.232 1.00 20.10 ? 231 ASP A CB 1 ATOM 1349 C CG . ASP A 1 179 ? -4.303 158.068 -14.295 1.00 26.61 ? 231 ASP A CG 1 ATOM 1350 O OD1 . ASP A 1 179 ? -3.973 158.275 -15.482 1.00 31.42 ? 231 ASP A OD1 1 ATOM 1351 O OD2 . ASP A 1 179 ? -5.047 157.127 -13.947 1.00 23.42 ? 231 ASP A OD2 1 ATOM 1352 N N . SER A 1 180 ? -7.110 159.890 -13.426 1.00 21.50 ? 232 SER A N 1 ATOM 1353 C CA . SER A 1 180 ? -8.491 159.621 -13.032 1.00 21.21 ? 232 SER A CA 1 ATOM 1354 C C . SER A 1 180 ? -8.782 158.138 -12.805 1.00 18.85 ? 232 SER A C 1 ATOM 1355 O O . SER A 1 180 ? -9.731 157.795 -12.103 1.00 23.89 ? 232 SER A O 1 ATOM 1356 C CB . SER A 1 180 ? -9.453 160.175 -14.085 1.00 24.61 ? 232 SER A CB 1 ATOM 1357 O OG . SER A 1 180 ? -9.228 159.572 -15.348 1.00 29.41 ? 232 SER A OG 1 ATOM 1358 N N . THR A 1 181 ? -7.972 157.261 -13.388 1.00 20.06 ? 233 THR A N 1 ATOM 1359 C CA . THR A 1 181 ? -8.145 155.830 -13.179 1.00 20.94 ? 233 THR A CA 1 ATOM 1360 C C . THR A 1 181 ? -7.506 155.412 -11.864 1.00 21.39 ? 233 THR A C 1 ATOM 1361 O O . THR A 1 181 ? -8.125 154.723 -11.058 1.00 21.28 ? 233 THR A O 1 ATOM 1362 C CB . THR A 1 181 ? -7.545 155.016 -14.329 1.00 30.05 ? 233 THR A CB 1 ATOM 1363 O OG1 . THR A 1 181 ? -8.189 155.398 -15.550 1.00 29.48 ? 233 THR A OG1 1 ATOM 1364 C CG2 . THR A 1 181 ? -7.736 153.519 -14.095 1.00 28.66 ? 233 THR A CG2 1 ATOM 1365 N N . VAL A 1 182 ? -6.266 155.835 -11.646 1.00 20.29 ? 234 VAL A N 1 ATOM 1366 C CA . VAL A 1 182 ? -5.598 155.549 -10.388 1.00 19.82 ? 234 VAL A CA 1 ATOM 1367 C C . VAL A 1 182 ? -6.394 156.163 -9.231 1.00 16.07 ? 234 VAL A C 1 ATOM 1368 O O . VAL A 1 182 ? -6.560 155.545 -8.178 1.00 18.81 ? 234 VAL A O 1 ATOM 1369 C CB . VAL A 1 182 ? -4.152 156.081 -10.392 1.00 17.09 ? 234 VAL A CB 1 ATOM 1370 C CG1 . VAL A 1 182 ? -3.526 156.010 -8.990 1.00 20.06 ? 234 VAL A CG1 1 ATOM 1371 C CG2 . VAL A 1 182 ? -3.317 155.297 -11.387 1.00 20.60 ? 234 VAL A CG2 1 ATOM 1372 N N . CYS A 1 183 ? -6.904 157.371 -9.450 1.00 17.47 ? 235 CYS A N 1 ATOM 1373 C CA . CYS A 1 183 ? -7.637 158.103 -8.424 1.00 17.57 ? 235 CYS A CA 1 ATOM 1374 C C . CYS A 1 183 ? -9.144 158.014 -8.623 1.00 19.71 ? 235 CYS A C 1 ATOM 1375 O O . CYS A 1 183 ? -9.849 159.008 -8.459 1.00 19.19 ? 235 CYS A O 1 ATOM 1376 C CB . CYS A 1 183 ? -7.217 159.570 -8.428 1.00 17.12 ? 235 CYS A CB 1 ATOM 1377 S SG . CYS A 1 183 ? -5.436 159.836 -8.251 1.00 19.24 ? 235 CYS A SG 1 ATOM 1378 N N . ASN A 1 184 ? -9.639 156.830 -8.963 1.00 18.60 ? 236 ASN A N 1 ATOM 1379 C CA . ASN A 1 184 ? -11.042 156.697 -9.339 1.00 20.38 ? 236 ASN A CA 1 ATOM 1380 C C . ASN A 1 184 ? -11.990 156.758 -8.144 1.00 23.85 ? 236 ASN A C 1 ATOM 1381 O O . ASN A 1 184 ? -13.205 156.696 -8.311 1.00 23.60 ? 236 ASN A O 1 ATOM 1382 C CB . ASN A 1 184 ? -11.267 155.397 -10.125 1.00 20.57 ? 236 ASN A CB 1 ATOM 1383 C CG . ASN A 1 184 ? -10.948 154.148 -9.328 1.00 26.35 ? 236 ASN A CG 1 ATOM 1384 O OD1 . ASN A 1 184 ? -10.693 154.194 -8.125 1.00 27.76 ? 236 ASN A OD1 1 ATOM 1385 N ND2 . ASN A 1 184 ? -10.974 153.008 -10.009 1.00 31.22 ? 236 ASN A ND2 1 ATOM 1386 N N . PHE A 1 185 ? -11.426 156.903 -6.948 1.00 20.44 ? 237 PHE A N 1 ATOM 1387 C CA . PHE A 1 185 ? -12.193 156.965 -5.708 1.00 19.49 ? 237 PHE A CA 1 ATOM 1388 C C . PHE A 1 185 ? -12.311 158.406 -5.226 1.00 17.92 ? 237 PHE A C 1 ATOM 1389 O O . PHE A 1 185 ? -12.812 158.664 -4.129 1.00 21.82 ? 237 PHE A O 1 ATOM 1390 C CB . PHE A 1 185 ? -11.525 156.114 -4.629 1.00 20.89 ? 237 PHE A CB 1 ATOM 1391 C CG . PHE A 1 185 ? -10.094 156.499 -4.384 1.00 18.45 ? 237 PHE A CG 1 ATOM 1392 C CD1 . PHE A 1 185 ? -9.078 155.950 -5.151 1.00 20.48 ? 237 PHE A CD1 1 ATOM 1393 C CD2 . PHE A 1 185 ? -9.772 157.449 -3.434 1.00 18.59 ? 237 PHE A CD2 1 ATOM 1394 C CE1 . PHE A 1 185 ? -7.765 156.321 -4.954 1.00 18.92 ? 237 PHE A CE1 1 ATOM 1395 C CE2 . PHE A 1 185 ? -8.459 157.824 -3.228 1.00 19.89 ? 237 PHE A CE2 1 ATOM 1396 C CZ . PHE A 1 185 ? -7.451 157.258 -3.990 1.00 17.19 ? 237 PHE A CZ 1 ATOM 1397 N N . VAL A 1 186 ? -11.842 159.347 -6.035 1.00 19.44 ? 238 VAL A N 1 ATOM 1398 C CA . VAL A 1 186 ? -11.948 160.756 -5.688 1.00 19.82 ? 238 VAL A CA 1 ATOM 1399 C C . VAL A 1 186 ? -12.165 161.568 -6.975 1.00 22.22 ? 238 VAL A C 1 ATOM 1400 O O . VAL A 1 186 ? -11.352 162.398 -7.370 1.00 25.19 ? 238 VAL A O 1 ATOM 1401 C CB . VAL A 1 186 ? -10.689 161.210 -4.867 1.00 23.28 ? 238 VAL A CB 1 ATOM 1402 C CG1 . VAL A 1 186 ? -9.401 160.960 -5.629 1.00 22.26 ? 238 VAL A CG1 1 ATOM 1403 C CG2 . VAL A 1 186 ? -10.812 162.645 -4.404 1.00 23.53 ? 238 VAL A CG2 1 ATOM 1404 N N . THR A 1 187 ? -13.298 161.304 -7.627 1.00 20.59 ? 239 THR A N 1 ATOM 1405 C CA . THR A 1 187 ? -13.670 161.994 -8.857 1.00 23.38 ? 239 THR A CA 1 ATOM 1406 C C . THR A 1 187 ? -15.066 162.590 -8.743 1.00 23.66 ? 239 THR A C 1 ATOM 1407 O O . THR A 1 187 ? -15.765 162.368 -7.755 1.00 22.71 ? 239 THR A O 1 ATOM 1408 C CB . THR A 1 187 ? -13.654 161.049 -10.066 1.00 23.93 ? 239 THR A CB 1 ATOM 1409 O OG1 . THR A 1 187 ? -14.706 160.091 -9.921 1.00 23.73 ? 239 THR A OG1 1 ATOM 1410 C CG2 . THR A 1 187 ? -12.316 160.326 -10.173 1.00 25.46 ? 239 THR A CG2 1 ATOM 1411 N N . GLU A 1 188 ? -15.458 163.346 -9.765 1.00 26.90 ? 240 GLU A N 1 ATOM 1412 C CA . GLU A 1 188 ? -16.816 163.880 -9.879 1.00 31.31 ? 240 GLU A CA 1 ATOM 1413 C C . GLU A 1 188 ? -17.882 162.824 -9.651 1.00 32.19 ? 240 GLU A C 1 ATOM 1414 O O . GLU A 1 188 ? -18.832 163.029 -8.898 1.00 32.00 ? 240 GLU A O 1 ATOM 1415 C CB . GLU A 1 188 ? -17.037 164.475 -11.266 1.00 37.98 ? 240 GLU A CB 1 ATOM 1416 C CG . GLU A 1 188 ? -16.803 165.951 -11.388 1.00 41.17 ? 240 GLU A CG 1 ATOM 1417 C CD . GLU A 1 188 ? -17.204 166.462 -12.757 1.00 44.96 ? 240 GLU A CD 1 ATOM 1418 O OE1 . GLU A 1 188 ? -18.369 166.237 -13.155 1.00 52.28 ? 240 GLU A OE1 1 ATOM 1419 O OE2 . GLU A 1 188 ? -16.357 167.071 -13.440 1.00 45.90 ? 240 GLU A OE2 1 ATOM 1420 N N . SER A 1 189 ? -17.717 161.695 -10.333 1.00 34.75 ? 241 SER A N 1 ATOM 1421 C CA . SER A 1 189 ? -18.729 160.648 -10.351 1.00 37.29 ? 241 SER A CA 1 ATOM 1422 C C . SER A 1 189 ? -18.606 159.686 -9.175 1.00 32.63 ? 241 SER A C 1 ATOM 1423 O O . SER A 1 189 ? -19.539 158.941 -8.881 1.00 36.37 ? 241 SER A O 1 ATOM 1424 C CB . SER A 1 189 ? -18.643 159.869 -11.664 1.00 40.20 ? 241 SER A CB 1 ATOM 1425 O OG . SER A 1 189 ? -17.354 159.311 -11.840 1.00 40.44 ? 241 SER A OG 1 ATOM 1426 N N . ASN A 1 190 ? -17.455 159.700 -8.508 1.00 26.14 ? 242 ASN A N 1 ATOM 1427 C CA . ASN A 1 190 ? -17.232 158.847 -7.346 1.00 23.26 ? 242 ASN A CA 1 ATOM 1428 C C . ASN A 1 190 ? -16.411 159.588 -6.294 1.00 24.28 ? 242 ASN A C 1 ATOM 1429 O O . ASN A 1 190 ? -15.220 159.328 -6.125 1.00 21.48 ? 242 ASN A O 1 ATOM 1430 C CB . ASN A 1 190 ? -16.530 157.556 -7.757 1.00 21.83 ? 242 ASN A CB 1 ATOM 1431 C CG . ASN A 1 190 ? -16.472 156.540 -6.634 1.00 26.70 ? 242 ASN A CG 1 ATOM 1432 O OD1 . ASN A 1 190 ? -17.319 156.536 -5.740 1.00 31.90 ? 242 ASN A OD1 1 ATOM 1433 N ND2 . ASN A 1 190 ? -15.474 155.664 -6.678 1.00 28.10 ? 242 ASN A ND2 1 ATOM 1434 N N . PRO A 1 191 ? -17.044 160.534 -5.592 1.00 22.12 ? 243 PRO A N 1 ATOM 1435 C CA . PRO A 1 191 ? -16.258 161.351 -4.665 1.00 19.45 ? 243 PRO A CA 1 ATOM 1436 C C . PRO A 1 191 ? -15.908 160.628 -3.372 1.00 20.27 ? 243 PRO A C 1 ATOM 1437 O O . PRO A 1 191 ? -16.543 159.642 -2.987 1.00 19.37 ? 243 PRO A O 1 ATOM 1438 C CB . PRO A 1 191 ? -17.169 162.549 -4.392 1.00 21.33 ? 243 PRO A CB 1 ATOM 1439 C CG . PRO A 1 191 ? -18.543 162.045 -4.620 1.00 24.62 ? 243 PRO A CG 1 ATOM 1440 C CD . PRO A 1 191 ? -18.441 160.991 -5.693 1.00 24.88 ? 243 PRO A CD 1 ATOM 1441 N N . LEU A 1 192 ? -14.866 161.129 -2.718 1.00 18.14 ? 244 LEU A N 1 ATOM 1442 C CA . LEU A 1 192 ? -14.441 160.628 -1.427 1.00 18.60 ? 244 LEU A CA 1 ATOM 1443 C C . LEU A 1 192 ? -15.229 161.360 -0.351 1.00 15.02 ? 244 LEU A C 1 ATOM 1444 O O . LEU A 1 192 ? -15.155 162.579 -0.257 1.00 17.20 ? 244 LEU A O 1 ATOM 1445 C CB . LEU A 1 192 ? -12.942 160.841 -1.254 1.00 17.76 ? 244 LEU A CB 1 ATOM 1446 C CG . LEU A 1 192 ? -12.253 160.258 -0.018 1.00 18.47 ? 244 LEU A CG 1 ATOM 1447 C CD1 . LEU A 1 192 ? -12.426 158.749 0.060 1.00 18.48 ? 244 LEU A CD1 1 ATOM 1448 C CD2 . LEU A 1 192 ? -10.778 160.646 -0.055 1.00 17.48 ? 244 LEU A CD2 1 ATOM 1449 N N . ARG A 1 193 ? -15.984 160.613 0.448 1.00 16.97 ? 245 ARG A N 1 ATOM 1450 C CA . ARG A 1 193 ? -16.931 161.224 1.379 1.00 19.00 ? 245 ARG A CA 1 ATOM 1451 C C . ARG A 1 193 ? -16.346 161.457 2.767 1.00 16.65 ? 245 ARG A C 1 ATOM 1452 O O . ARG A 1 193 ? -15.758 160.553 3.360 1.00 18.54 ? 245 ARG A O 1 ATOM 1453 C CB . ARG A 1 193 ? -18.175 160.346 1.529 1.00 22.20 ? 245 ARG A CB 1 ATOM 1454 C CG . ARG A 1 193 ? -18.867 159.976 0.233 1.00 28.97 ? 245 ARG A CG 1 ATOM 1455 C CD . ARG A 1 193 ? -19.861 161.023 -0.215 1.00 30.32 ? 245 ARG A CD 1 ATOM 1456 N NE . ARG A 1 193 ? -20.605 160.564 -1.386 1.00 31.58 ? 245 ARG A NE 1 ATOM 1457 C CZ . ARG A 1 193 ? -21.211 161.367 -2.252 1.00 29.84 ? 245 ARG A CZ 1 ATOM 1458 N NH1 . ARG A 1 193 ? -21.173 162.685 -2.091 1.00 32.36 ? 245 ARG A NH1 1 ATOM 1459 N NH2 . ARG A 1 193 ? -21.849 160.851 -3.291 1.00 31.84 ? 245 ARG A NH2 1 ATOM 1460 N N . PHE A 1 194 ? -16.539 162.665 3.287 1.00 16.43 ? 246 PHE A N 1 ATOM 1461 C CA . PHE A 1 194 ? -16.214 162.984 4.673 1.00 16.61 ? 246 PHE A CA 1 ATOM 1462 C C . PHE A 1 194 ? -17.506 162.951 5.472 1.00 17.39 ? 246 PHE A C 1 ATOM 1463 O O . PHE A 1 194 ? -17.657 162.157 6.397 1.00 17.78 ? 246 PHE A O 1 ATOM 1464 C CB . PHE A 1 194 ? -15.542 164.359 4.767 1.00 18.60 ? 246 PHE A CB 1 ATOM 1465 C CG . PHE A 1 194 ? -15.128 164.770 6.168 1.00 14.32 ? 246 PHE A CG 1 ATOM 1466 C CD1 . PHE A 1 194 ? -14.835 163.839 7.151 1.00 13.39 ? 246 PHE A CD1 1 ATOM 1467 C CD2 . PHE A 1 194 ? -15.022 166.114 6.481 1.00 15.36 ? 246 PHE A CD2 1 ATOM 1468 C CE1 . PHE A 1 194 ? -14.445 164.253 8.419 1.00 15.61 ? 246 PHE A CE1 1 ATOM 1469 C CE2 . PHE A 1 194 ? -14.631 166.529 7.745 1.00 15.52 ? 246 PHE A CE2 1 ATOM 1470 C CZ . PHE A 1 194 ? -14.347 165.601 8.709 1.00 15.48 ? 246 PHE A CZ 1 ATOM 1471 N N . LEU A 1 195 ? -18.435 163.821 5.091 1.00 18.73 ? 247 LEU A N 1 ATOM 1472 C CA . LEU A 1 195 ? -19.792 163.794 5.626 1.00 19.03 ? 247 LEU A CA 1 ATOM 1473 C C . LEU A 1 195 ? -20.698 163.266 4.525 1.00 20.44 ? 247 LEU A C 1 ATOM 1474 O O . LEU A 1 195 ? -21.007 163.977 3.574 1.00 22.16 ? 247 LEU A O 1 ATOM 1475 C CB . LEU A 1 195 ? -20.228 165.182 6.093 1.00 19.49 ? 247 LEU A CB 1 ATOM 1476 C CG . LEU A 1 195 ? -19.182 165.917 6.931 1.00 19.25 ? 247 LEU A CG 1 ATOM 1477 C CD1 . LEU A 1 195 ? -19.701 167.280 7.367 1.00 23.80 ? 247 LEU A CD1 1 ATOM 1478 C CD2 . LEU A 1 195 ? -18.756 165.082 8.134 1.00 18.29 ? 247 LEU A CD2 1 ATOM 1479 N N . ASP A 1 196 ? -21.081 162.001 4.649 1.00 22.70 ? 248 ASP A N 1 ATOM 1480 C CA . ASP A 1 196 ? -21.869 161.327 3.625 1.00 24.25 ? 248 ASP A CA 1 ATOM 1481 C C . ASP A 1 196 ? -23.346 161.646 3.800 1.00 26.09 ? 248 ASP A C 1 ATOM 1482 O O . ASP A 1 196 ? -24.024 161.069 4.647 1.00 27.38 ? 248 ASP A O 1 ATOM 1483 C CB . ASP A 1 196 ? -21.647 159.817 3.681 1.00 25.36 ? 248 ASP A CB 1 ATOM 1484 C CG . ASP A 1 196 ? -22.246 159.099 2.486 1.00 32.65 ? 248 ASP A CG 1 ATOM 1485 O OD1 . ASP A 1 196 ? -22.920 159.763 1.669 1.00 28.97 ? 248 ASP A OD1 1 ATOM 1486 O OD2 . ASP A 1 196 ? -22.044 157.873 2.366 1.00 30.24 ? 248 ASP A OD2 1 ATOM 1487 N N . THR A 1 197 ? -23.834 162.567 2.983 1.00 28.09 ? 249 THR A N 1 ATOM 1488 C CA . THR A 1 197 ? -25.197 163.059 3.109 1.00 30.56 ? 249 THR A CA 1 ATOM 1489 C C . THR A 1 197 ? -26.200 162.096 2.478 1.00 39.58 ? 249 THR A C 1 ATOM 1490 O O . THR A 1 197 ? -27.412 162.269 2.623 1.00 39.29 ? 249 THR A O 1 ATOM 1491 C CB . THR A 1 197 ? -25.327 164.448 2.466 1.00 31.18 ? 249 THR A CB 1 ATOM 1492 O OG1 . THR A 1 197 ? -24.923 164.377 1.093 1.00 30.37 ? 249 THR A OG1 1 ATOM 1493 C CG2 . THR A 1 197 ? -24.439 165.450 3.204 1.00 32.53 ? 249 THR A CG2 1 ATOM 1494 N N . THR A 1 198 ? -25.692 161.076 1.789 1.00 35.02 ? 250 THR A N 1 ATOM 1495 C CA . THR A 1 198 ? -26.546 160.043 1.214 1.00 39.65 ? 250 THR A CA 1 ATOM 1496 C C . THR A 1 198 ? -26.945 159.011 2.272 1.00 46.52 ? 250 THR A C 1 ATOM 1497 O O . THR A 1 198 ? -27.712 158.089 1.988 1.00 49.96 ? 250 THR A O 1 ATOM 1498 C CB . THR A 1 198 ? -25.857 159.318 0.036 1.00 36.18 ? 250 THR A CB 1 ATOM 1499 O OG1 . THR A 1 198 ? -24.817 158.465 0.530 1.00 40.60 ? 250 THR A OG1 1 ATOM 1500 C CG2 . THR A 1 198 ? -25.269 160.321 -0.953 1.00 38.98 ? 250 THR A CG2 1 ATOM 1501 N N . GLN A 1 199 ? -26.425 159.173 3.488 1.00 39.33 ? 251 GLN A N 1 ATOM 1502 C CA . GLN A 1 199 ? -26.751 158.287 4.602 1.00 36.96 ? 251 GLN A CA 1 ATOM 1503 C C . GLN A 1 199 ? -27.126 159.103 5.835 1.00 42.83 ? 251 GLN A C 1 ATOM 1504 O O . GLN A 1 199 ? -26.326 159.266 6.758 1.00 37.71 ? 251 GLN A O 1 ATOM 1505 C CB . GLN A 1 199 ? -25.573 157.357 4.914 1.00 39.01 ? 251 GLN A CB 1 ATOM 1506 C CG . GLN A 1 199 ? -25.154 156.479 3.740 1.00 41.73 ? 251 GLN A CG 1 ATOM 1507 C CD . GLN A 1 199 ? -23.904 155.660 4.028 1.00 49.32 ? 251 GLN A CD 1 ATOM 1508 O OE1 . GLN A 1 199 ? -23.238 155.859 5.045 1.00 39.65 ? 251 GLN A OE1 1 ATOM 1509 N NE2 . GLN A 1 199 ? -23.579 154.735 3.128 1.00 47.73 ? 251 GLN A NE2 1 ATOM 1510 N N . ARG A 1 200 ? -28.351 159.618 5.843 1.00 40.85 ? 252 ARG A N 1 ATOM 1511 C CA . ARG A 1 200 ? -28.832 160.426 6.956 1.00 42.03 ? 252 ARG A CA 1 ATOM 1512 C C . ARG A 1 200 ? -29.060 159.571 8.198 1.00 40.01 ? 252 ARG A C 1 ATOM 1513 O O . ARG A 1 200 ? -29.180 158.348 8.108 1.00 48.63 ? 252 ARG A O 1 ATOM 1514 C CB . ARG A 1 200 ? -30.129 161.146 6.576 1.00 45.50 ? 252 ARG A CB 1 ATOM 1515 C CG . ARG A 1 200 ? -29.990 162.130 5.423 1.00 49.45 ? 252 ARG A CG 1 ATOM 1516 C CD . ARG A 1 200 ? -31.252 162.965 5.266 1.00 54.87 ? 252 ARG A CD 1 ATOM 1517 N NE . ARG A 1 200 ? -30.947 164.390 5.140 1.00 59.29 ? 252 ARG A NE 1 ATOM 1518 C CZ . ARG A 1 200 ? -31.652 165.372 5.698 1.00 65.14 ? 252 ARG A CZ 1 ATOM 1519 N NH1 . ARG A 1 200 ? -32.724 165.109 6.438 1.00 64.22 ? 252 ARG A NH1 1 ATOM 1520 N NH2 . ARG A 1 200 ? -31.280 166.633 5.515 1.00 60.37 ? 252 ARG A NH2 1 ATOM 1521 N N . GLN A 1 201 ? -29.114 160.227 9.354 1.00 45.27 ? 253 GLN A N 1 ATOM 1522 C CA . GLN A 1 201 ? -29.382 159.555 10.621 1.00 59.04 ? 253 GLN A CA 1 ATOM 1523 C C . GLN A 1 201 ? -30.468 160.285 11.401 1.00 58.64 ? 253 GLN A C 1 ATOM 1524 O O . GLN A 1 201 ? -30.842 161.408 11.061 1.00 56.42 ? 253 GLN A O 1 ATOM 1525 C CB . GLN A 1 201 ? -28.114 159.469 11.468 1.00 49.73 ? 253 GLN A CB 1 ATOM 1526 C CG . GLN A 1 201 ? -26.991 158.667 10.841 1.00 45.41 ? 253 GLN A CG 1 ATOM 1527 C CD . GLN A 1 201 ? -25.725 158.718 11.670 1.00 49.06 ? 253 GLN A CD 1 ATOM 1528 O OE1 . GLN A 1 201 ? -25.752 159.102 12.841 1.00 60.40 ? 253 GLN A OE1 1 ATOM 1529 N NE2 . GLN A 1 201 ? -24.606 158.338 11.067 1.00 48.99 ? 253 GLN A NE2 1 ATOM 1530 N N . SER A 1 202 ? -30.967 159.641 12.451 1.00 62.16 ? 254 SER A N 1 ATOM 1531 C CA . SER A 1 202 ? -31.955 160.255 13.328 1.00 65.05 ? 254 SER A CA 1 ATOM 1532 C C . SER A 1 202 ? -31.339 161.440 14.070 1.00 65.38 ? 254 SER A C 1 ATOM 1533 O O . SER A 1 202 ? -32.026 162.413 14.388 1.00 60.05 ? 254 SER A O 1 ATOM 1534 C CB . SER A 1 202 ? -32.498 159.230 14.327 1.00 61.80 ? 254 SER A CB 1 ATOM 1535 O OG . SER A 1 202 ? -31.717 159.208 15.510 1.00 65.83 ? 254 SER A OG 1 ATOM 1536 N N . THR A 1 203 ? -30.038 161.350 14.335 1.00 66.70 ? 255 THR A N 1 ATOM 1537 C CA . THR A 1 203 ? -29.322 162.382 15.078 1.00 60.23 ? 255 THR A CA 1 ATOM 1538 C C . THR A 1 203 ? -28.881 163.536 14.176 1.00 60.68 ? 255 THR A C 1 ATOM 1539 O O . THR A 1 203 ? -28.924 164.697 14.584 1.00 59.19 ? 255 THR A O 1 ATOM 1540 C CB . THR A 1 203 ? -28.076 161.800 15.783 1.00 66.93 ? 255 THR A CB 1 ATOM 1541 O OG1 . THR A 1 203 ? -28.436 160.615 16.504 1.00 67.52 ? 255 THR A OG1 1 ATOM 1542 C CG2 . THR A 1 203 ? -27.473 162.818 16.750 1.00 60.87 ? 255 THR A CG2 1 ATOM 1543 N N . GLN A 1 204 ? -28.457 163.215 12.956 1.00 57.08 ? 256 GLN A N 1 ATOM 1544 C CA . GLN A 1 204 ? -27.920 164.223 12.042 1.00 54.38 ? 256 GLN A CA 1 ATOM 1545 C C . GLN A 1 204 ? -28.114 163.805 10.580 1.00 43.27 ? 256 GLN A C 1 ATOM 1546 O O . GLN A 1 204 ? -28.289 162.622 10.290 1.00 49.79 ? 256 GLN A O 1 ATOM 1547 C CB . GLN A 1 204 ? -26.437 164.457 12.345 1.00 53.33 ? 256 GLN A CB 1 ATOM 1548 C CG . GLN A 1 204 ? -25.513 163.388 11.768 1.00 46.57 ? 256 GLN A CG 1 ATOM 1549 C CD . GLN A 1 204 ? -24.332 163.062 12.663 1.00 47.37 ? 256 GLN A CD 1 ATOM 1550 O OE1 . GLN A 1 204 ? -24.349 163.324 13.866 1.00 55.86 ? 256 GLN A OE1 1 ATOM 1551 N NE2 . GLN A 1 204 ? -23.297 162.473 12.076 1.00 43.94 ? 256 GLN A NE2 1 ATOM 1552 N N . PRO A 1 205 ? -28.079 164.777 9.651 1.00 42.05 ? 257 PRO A N 1 ATOM 1553 C CA . PRO A 1 205 ? -28.393 164.518 8.238 1.00 43.49 ? 257 PRO A CA 1 ATOM 1554 C C . PRO A 1 205 ? -27.233 163.943 7.417 1.00 37.47 ? 257 PRO A C 1 ATOM 1555 O O . PRO A 1 205 ? -27.147 164.195 6.213 1.00 38.37 ? 257 PRO A O 1 ATOM 1556 C CB . PRO A 1 205 ? -28.781 165.908 7.723 1.00 47.34 ? 257 PRO A CB 1 ATOM 1557 C CG . PRO A 1 205 ? -27.941 166.829 8.525 1.00 43.75 ? 257 PRO A CG 1 ATOM 1558 C CD . PRO A 1 205 ? -27.860 166.215 9.900 1.00 48.28 ? 257 PRO A CD 1 ATOM 1559 N N . TYR A 1 206 ? -26.364 163.167 8.055 1.00 30.16 ? 258 TYR A N 1 ATOM 1560 C CA . TYR A 1 206 ? -25.242 162.551 7.357 1.00 31.54 ? 258 TYR A CA 1 ATOM 1561 C C . TYR A 1 206 ? -24.571 161.521 8.247 1.00 22.48 ? 258 TYR A C 1 ATOM 1562 O O . TYR A 1 206 ? -24.803 161.489 9.455 1.00 26.36 ? 258 TYR A O 1 ATOM 1563 C CB . TYR A 1 206 ? -24.216 163.607 6.931 1.00 28.68 ? 258 TYR A CB 1 ATOM 1564 C CG . TYR A 1 206 ? -23.695 164.431 8.085 1.00 30.88 ? 258 TYR A CG 1 ATOM 1565 C CD1 . TYR A 1 206 ? -22.608 164.004 8.837 1.00 25.68 ? 258 TYR A CD1 1 ATOM 1566 C CD2 . TYR A 1 206 ? -24.300 165.630 8.433 1.00 25.79 ? 258 TYR A CD2 1 ATOM 1567 C CE1 . TYR A 1 206 ? -22.134 164.752 9.898 1.00 29.10 ? 258 TYR A CE1 1 ATOM 1568 C CE2 . TYR A 1 206 ? -23.835 166.387 9.490 1.00 31.19 ? 258 TYR A CE2 1 ATOM 1569 C CZ . TYR A 1 206 ? -22.749 165.944 10.220 1.00 26.72 ? 258 TYR A CZ 1 ATOM 1570 O OH . TYR A 1 206 ? -22.284 166.696 11.273 1.00 29.54 ? 258 TYR A OH 1 ATOM 1571 N N . THR A 1 207 ? -23.739 160.682 7.640 1.00 25.02 ? 259 THR A N 1 ATOM 1572 C CA . THR A 1 207 ? -22.875 159.785 8.391 1.00 23.13 ? 259 THR A CA 1 ATOM 1573 C C . THR A 1 207 ? -21.435 160.268 8.227 1.00 22.76 ? 259 THR A C 1 ATOM 1574 O O . THR A 1 207 ? -21.002 160.583 7.117 1.00 20.44 ? 259 THR A O 1 ATOM 1575 C CB . THR A 1 207 ? -23.006 158.325 7.923 1.00 28.25 ? 259 THR A CB 1 ATOM 1576 O OG1 . THR A 1 207 ? -24.364 157.892 8.079 1.00 32.17 ? 259 THR A OG1 1 ATOM 1577 C CG2 . THR A 1 207 ? -22.102 157.414 8.745 1.00 27.95 ? 259 THR A CG2 1 ATOM 1578 N N . GLU A 1 208 ? -20.711 160.330 9.340 1.00 20.21 ? 260 GLU A N 1 ATOM 1579 C CA . GLU A 1 208 ? -19.340 160.838 9.348 1.00 21.15 ? 260 GLU A CA 1 ATOM 1580 C C . GLU A 1 208 ? -18.331 159.746 9.015 1.00 16.55 ? 260 GLU A C 1 ATOM 1581 O O . GLU A 1 208 ? -18.341 158.678 9.621 1.00 18.03 ? 260 GLU A O 1 ATOM 1582 C CB . GLU A 1 208 ? -19.011 161.444 10.714 1.00 20.20 ? 260 GLU A CB 1 ATOM 1583 C CG . GLU A 1 208 ? -17.617 162.065 10.801 1.00 21.86 ? 260 GLU A CG 1 ATOM 1584 C CD . GLU A 1 208 ? -17.231 162.457 12.218 1.00 34.13 ? 260 GLU A CD 1 ATOM 1585 O OE1 . GLU A 1 208 ? -18.122 162.502 13.096 1.00 31.92 ? 260 GLU A OE1 1 ATOM 1586 O OE2 . GLU A 1 208 ? -16.032 162.722 12.451 1.00 28.59 ? 260 GLU A OE2 1 ATOM 1587 N N . TYR A 1 209 ? -17.457 160.038 8.054 1.00 15.42 ? 261 TYR A N 1 ATOM 1588 C CA . TYR A 1 209 ? -16.338 159.168 7.724 1.00 17.33 ? 261 TYR A CA 1 ATOM 1589 C C . TYR A 1 209 ? -15.052 159.989 7.827 1.00 17.94 ? 261 TYR A C 1 ATOM 1590 O O . TYR A 1 209 ? -14.901 160.766 8.765 1.00 16.70 ? 261 TYR A O 1 ATOM 1591 C CB . TYR A 1 209 ? -16.523 158.551 6.330 1.00 17.78 ? 261 TYR A CB 1 ATOM 1592 C CG . TYR A 1 209 ? -17.708 157.611 6.248 1.00 19.59 ? 261 TYR A CG 1 ATOM 1593 C CD1 . TYR A 1 209 ? -17.680 156.373 6.879 1.00 20.43 ? 261 TYR A CD1 1 ATOM 1594 C CD2 . TYR A 1 209 ? -18.851 157.964 5.546 1.00 23.48 ? 261 TYR A CD2 1 ATOM 1595 C CE1 . TYR A 1 209 ? -18.755 155.508 6.809 1.00 24.59 ? 261 TYR A CE1 1 ATOM 1596 C CE2 . TYR A 1 209 ? -19.935 157.104 5.471 1.00 23.04 ? 261 TYR A CE2 1 ATOM 1597 C CZ . TYR A 1 209 ? -19.878 155.880 6.104 1.00 25.44 ? 261 TYR A CZ 1 ATOM 1598 O OH . TYR A 1 209 ? -20.947 155.017 6.041 1.00 28.79 ? 261 TYR A OH 1 ATOM 1599 N N . ALA A 1 210 ? -14.150 159.830 6.864 1.00 13.98 ? 262 ALA A N 1 ATOM 1600 C CA . ALA A 1 210 ? -12.866 160.526 6.864 1.00 13.74 ? 262 ALA A CA 1 ATOM 1601 C C . ALA A 1 210 ? -12.203 160.312 5.518 1.00 15.31 ? 262 ALA A C 1 ATOM 1602 O O . ALA A 1 210 ? -12.486 159.322 4.848 1.00 16.20 ? 262 ALA A O 1 ATOM 1603 C CB . ALA A 1 210 ? -11.979 160.013 7.970 1.00 15.57 ? 262 ALA A CB 1 ATOM 1604 N N . PHE A 1 211 ? -11.320 161.225 5.116 1.00 14.20 ? 263 PHE A N 1 ATOM 1605 C CA . PHE A 1 211 ? -10.554 161.014 3.887 1.00 13.36 ? 263 PHE A CA 1 ATOM 1606 C C . PHE A 1 211 ? -9.433 159.978 4.067 1.00 12.38 ? 263 PHE A C 1 ATOM 1607 O O . PHE A 1 211 ? -8.904 159.468 3.081 1.00 14.83 ? 263 PHE A O 1 ATOM 1608 C CB . PHE A 1 211 ? -9.937 162.320 3.383 1.00 13.73 ? 263 PHE A CB 1 ATOM 1609 C CG . PHE A 1 211 ? -10.934 163.335 2.870 1.00 13.35 ? 263 PHE A CG 1 ATOM 1610 C CD1 . PHE A 1 211 ? -12.262 163.003 2.613 1.00 14.92 ? 263 PHE A CD1 1 ATOM 1611 C CD2 . PHE A 1 211 ? -10.528 164.637 2.634 1.00 15.54 ? 263 PHE A CD2 1 ATOM 1612 C CE1 . PHE A 1 211 ? -13.146 163.960 2.130 1.00 14.98 ? 263 PHE A CE1 1 ATOM 1613 C CE2 . PHE A 1 211 ? -11.410 165.590 2.160 1.00 15.80 ? 263 PHE A CE2 1 ATOM 1614 C CZ . PHE A 1 211 ? -12.717 165.251 1.909 1.00 14.86 ? 263 PHE A CZ 1 ATOM 1615 N N . HIS A 1 212 ? -9.070 159.688 5.315 1.00 13.40 ? 264 HIS A N 1 ATOM 1616 C CA . HIS A 1 212 ? -8.009 158.738 5.636 1.00 14.47 ? 264 HIS A CA 1 ATOM 1617 C C . HIS A 1 212 ? -8.162 158.286 7.083 1.00 12.94 ? 264 HIS A C 1 ATOM 1618 O O . HIS A 1 212 ? -8.817 158.956 7.880 1.00 15.23 ? 264 HIS A O 1 ATOM 1619 C CB . HIS A 1 212 ? -6.634 159.372 5.421 1.00 12.86 ? 264 HIS A CB 1 ATOM 1620 C CG . HIS A 1 212 ? -6.349 160.500 6.356 1.00 12.49 ? 264 HIS A CG 1 ATOM 1621 N ND1 . HIS A 1 212 ? -5.461 160.390 7.405 1.00 11.35 ? 264 HIS A ND1 1 ATOM 1622 C CD2 . HIS A 1 212 ? -6.857 161.752 6.419 1.00 14.93 ? 264 HIS A CD2 1 ATOM 1623 C CE1 . HIS A 1 212 ? -5.420 161.536 8.063 1.00 11.38 ? 264 HIS A CE1 1 ATOM 1624 N NE2 . HIS A 1 212 ? -6.263 162.378 7.489 1.00 14.61 ? 264 HIS A NE2 1 ATOM 1625 N N . GLY A 1 213 ? -7.554 157.151 7.417 1.00 14.43 ? 265 GLY A N 1 ATOM 1626 C CA . GLY A 1 213 ? -7.607 156.615 8.764 1.00 15.44 ? 265 GLY A CA 1 ATOM 1627 C C . GLY A 1 213 ? -8.788 155.701 8.998 1.00 18.60 ? 265 GLY A C 1 ATOM 1628 O O . GLY A 1 213 ? -9.712 155.646 8.187 1.00 17.42 ? 265 GLY A O 1 ATOM 1629 N N . LYS A 1 214 ? -8.747 154.982 10.114 1.00 16.53 ? 266 LYS A N 1 ATOM 1630 C CA . LYS A 1 214 ? -9.802 154.037 10.466 1.00 16.08 ? 266 LYS A CA 1 ATOM 1631 C C . LYS A 1 214 ? -10.547 154.453 11.731 1.00 18.61 ? 266 LYS A C 1 ATOM 1632 O O . LYS A 1 214 ? -11.365 153.691 12.257 1.00 21.18 ? 266 LYS A O 1 ATOM 1633 C CB . LYS A 1 214 ? -9.213 152.637 10.621 1.00 19.02 ? 266 LYS A CB 1 ATOM 1634 C CG . LYS A 1 214 ? -8.824 152.032 9.273 1.00 25.67 ? 266 LYS A CG 1 ATOM 1635 C CD . LYS A 1 214 ? -8.705 150.527 9.318 1.00 23.74 ? 266 LYS A CD 1 ATOM 1636 C CE . LYS A 1 214 ? -8.608 149.958 7.915 1.00 27.20 ? 266 LYS A CE 1 ATOM 1637 N NZ . LYS A 1 214 ? -8.644 148.477 7.904 1.00 31.22 ? 266 LYS A NZ 1 ATOM 1638 N N . GLY A 1 215 ? -10.278 155.669 12.201 1.00 15.58 ? 267 GLY A N 1 ATOM 1639 C CA . GLY A 1 215 ? -11.038 156.266 13.285 1.00 16.65 ? 267 GLY A CA 1 ATOM 1640 C C . GLY A 1 215 ? -10.416 156.093 14.654 1.00 16.03 ? 267 GLY A C 1 ATOM 1641 O O . GLY A 1 215 ? -9.506 155.277 14.847 1.00 17.16 ? 267 GLY A O 1 ATOM 1642 N N . GLY A 1 216 ? -10.907 156.879 15.605 1.00 14.27 ? 268 GLY A N 1 ATOM 1643 C CA . GLY A 1 216 ? -10.541 156.723 17.000 1.00 16.53 ? 268 GLY A CA 1 ATOM 1644 C C . GLY A 1 216 ? -9.488 157.703 17.470 1.00 16.33 ? 268 GLY A C 1 ATOM 1645 O O . GLY A 1 216 ? -9.024 157.600 18.602 1.00 18.92 ? 268 GLY A O 1 ATOM 1646 N N . HIS A 1 217 ? -9.131 158.659 16.616 1.00 14.90 ? 269 HIS A N 1 ATOM 1647 C CA . HIS A 1 217 ? -8.014 159.564 16.895 1.00 15.16 ? 269 HIS A CA 1 ATOM 1648 C C . HIS A 1 217 ? -8.479 160.942 17.342 1.00 13.90 ? 269 HIS A C 1 ATOM 1649 O O . HIS A 1 217 ? -9.608 161.344 17.063 1.00 16.12 ? 269 HIS A O 1 ATOM 1650 C CB . HIS A 1 217 ? -7.135 159.711 15.653 1.00 13.59 ? 269 HIS A CB 1 ATOM 1651 C CG . HIS A 1 217 ? -6.739 158.409 15.038 1.00 14.18 ? 269 HIS A CG 1 ATOM 1652 N ND1 . HIS A 1 217 ? -5.946 157.490 15.693 1.00 16.76 ? 269 HIS A ND1 1 ATOM 1653 C CD2 . HIS A 1 217 ? -7.030 157.864 13.833 1.00 13.76 ? 269 HIS A CD2 1 ATOM 1654 C CE1 . HIS A 1 217 ? -5.766 156.437 14.914 1.00 15.11 ? 269 HIS A CE1 1 ATOM 1655 N NE2 . HIS A 1 217 ? -6.411 156.641 13.780 1.00 14.52 ? 269 HIS A NE2 1 ATOM 1656 N N . LYS A 1 218 ? -7.601 161.671 18.029 1.00 13.72 ? 270 LYS A N 1 ATOM 1657 C CA . LYS A 1 218 ? -7.891 163.037 18.433 1.00 13.54 ? 270 LYS A CA 1 ATOM 1658 C C . LYS A 1 218 ? -7.694 163.986 17.261 1.00 14.71 ? 270 LYS A C 1 ATOM 1659 O O . LYS A 1 218 ? -6.593 164.084 16.710 1.00 14.06 ? 270 LYS A O 1 ATOM 1660 C CB . LYS A 1 218 ? -7.001 163.445 19.613 1.00 16.97 ? 270 LYS A CB 1 ATOM 1661 C CG . LYS A 1 218 ? -7.302 162.665 20.885 1.00 19.62 ? 270 LYS A CG 1 ATOM 1662 C CD . LYS A 1 218 ? -6.213 162.844 21.938 1.00 25.07 ? 270 LYS A CD 1 ATOM 1663 C CE . LYS A 1 218 ? -6.255 161.731 22.985 1.00 33.73 ? 270 LYS A CE 1 ATOM 1664 N NZ . LYS A 1 218 ? -5.968 160.389 22.392 1.00 40.26 ? 270 LYS A NZ 1 ATOM 1665 N N . GLY A 1 219 ? -8.758 164.692 16.885 1.00 14.99 ? 271 GLY A N 1 ATOM 1666 C CA . GLY A 1 219 ? -8.731 165.551 15.715 1.00 12.91 ? 271 GLY A CA 1 ATOM 1667 C C . GLY A 1 219 ? -9.547 166.820 15.877 1.00 15.51 ? 271 GLY A C 1 ATOM 1668 O O . GLY A 1 219 ? -10.133 167.081 16.930 1.00 14.70 ? 271 GLY A O 1 ATOM 1669 N N . TYR A 1 220 ? -9.574 167.620 14.823 1.00 12.87 ? 272 TYR A N 1 ATOM 1670 C CA . TYR A 1 220 ? -10.220 168.917 14.888 1.00 13.07 ? 272 TYR A CA 1 ATOM 1671 C C . TYR A 1 220 ? -11.730 168.760 14.912 1.00 13.71 ? 272 TYR A C 1 ATOM 1672 O O . TYR A 1 220 ? -12.272 167.767 14.436 1.00 14.80 ? 272 TYR A O 1 ATOM 1673 C CB . TYR A 1 220 ? -9.772 169.811 13.724 1.00 14.59 ? 272 TYR A CB 1 ATOM 1674 C CG . TYR A 1 220 ? -10.510 169.707 12.396 1.00 14.17 ? 272 TYR A CG 1 ATOM 1675 C CD1 . TYR A 1 220 ? -10.269 168.664 11.508 1.00 14.41 ? 272 TYR A CD1 1 ATOM 1676 C CD2 . TYR A 1 220 ? -11.386 170.711 12.001 1.00 14.91 ? 272 TYR A CD2 1 ATOM 1677 C CE1 . TYR A 1 220 ? -10.911 168.607 10.283 1.00 13.47 ? 272 TYR A CE1 1 ATOM 1678 C CE2 . TYR A 1 220 ? -12.029 170.662 10.780 1.00 14.75 ? 272 TYR A CE2 1 ATOM 1679 C CZ . TYR A 1 220 ? -11.793 169.607 9.928 1.00 15.24 ? 272 TYR A CZ 1 ATOM 1680 O OH . TYR A 1 220 ? -12.432 169.571 8.708 1.00 16.93 ? 272 TYR A OH 1 ATOM 1681 N N . ASP A 1 221 ? -12.380 169.741 15.530 1.00 13.99 ? 273 ASP A N 1 ATOM 1682 C CA . ASP A 1 221 ? -13.832 169.779 15.660 1.00 14.14 ? 273 ASP A CA 1 ATOM 1683 C C . ASP A 1 221 ? -14.423 170.355 14.375 1.00 14.95 ? 273 ASP A C 1 ATOM 1684 O O . ASP A 1 221 ? -14.591 171.564 14.243 1.00 16.64 ? 273 ASP A O 1 ATOM 1685 C CB . ASP A 1 221 ? -14.210 170.609 16.887 1.00 16.58 ? 273 ASP A CB 1 ATOM 1686 C CG . ASP A 1 221 ? -15.708 170.687 17.112 1.00 16.58 ? 273 ASP A CG 1 ATOM 1687 O OD1 . ASP A 1 221 ? -16.462 170.036 16.361 1.00 16.74 ? 273 ASP A OD1 1 ATOM 1688 O OD2 . ASP A 1 221 ? -16.116 171.394 18.057 1.00 17.95 ? 273 ASP A OD2 1 ATOM 1689 N N . TYR A 1 222 ? -14.714 169.479 13.419 1.00 15.38 ? 274 TYR A N 1 ATOM 1690 C CA . TYR A 1 222 ? -15.172 169.917 12.107 1.00 17.05 ? 274 TYR A CA 1 ATOM 1691 C C . TYR A 1 222 ? -16.568 170.511 12.211 1.00 17.90 ? 274 TYR A C 1 ATOM 1692 O O . TYR A 1 222 ? -16.918 171.404 11.455 1.00 17.84 ? 274 TYR A O 1 ATOM 1693 C CB . TYR A 1 222 ? -15.174 168.753 11.097 1.00 16.48 ? 274 TYR A CB 1 ATOM 1694 C CG . TYR A 1 222 ? -16.347 167.813 11.269 1.00 20.05 ? 274 TYR A CG 1 ATOM 1695 C CD1 . TYR A 1 222 ? -17.590 168.113 10.716 1.00 21.45 ? 274 TYR A CD1 1 ATOM 1696 C CD2 . TYR A 1 222 ? -16.219 166.642 11.997 1.00 23.77 ? 274 TYR A CD2 1 ATOM 1697 C CE1 . TYR A 1 222 ? -18.669 167.272 10.894 1.00 23.41 ? 274 TYR A CE1 1 ATOM 1698 C CE2 . TYR A 1 222 ? -17.289 165.792 12.174 1.00 28.10 ? 274 TYR A CE2 1 ATOM 1699 C CZ . TYR A 1 222 ? -18.512 166.111 11.621 1.00 29.49 ? 274 TYR A CZ 1 ATOM 1700 O OH . TYR A 1 222 ? -19.581 165.264 11.798 1.00 42.28 ? 274 TYR A OH 1 ATOM 1701 N N . LYS A 1 223 ? -17.362 169.998 13.146 1.00 18.97 ? 275 LYS A N 1 ATOM 1702 C CA . LYS A 1 223 ? -18.770 170.384 13.239 1.00 18.37 ? 275 LYS A CA 1 ATOM 1703 C C . LYS A 1 223 ? -18.992 171.675 14.002 1.00 19.13 ? 275 LYS A C 1 ATOM 1704 O O . LYS A 1 223 ? -19.833 172.494 13.618 1.00 18.87 ? 275 LYS A O 1 ATOM 1705 C CB . LYS A 1 223 ? -19.577 169.275 13.909 1.00 20.89 ? 275 LYS A CB 1 ATOM 1706 C CG . LYS A 1 223 ? -21.063 169.593 14.031 1.00 28.18 ? 275 LYS A CG 1 ATOM 1707 C CD . LYS A 1 223 ? -21.810 168.415 14.612 1.00 29.29 ? 275 LYS A CD 1 ATOM 1708 C CE . LYS A 1 223 ? -23.308 168.588 14.465 1.00 47.05 ? 275 LYS A CE 1 ATOM 1709 N NZ . LYS A 1 223 ? -24.037 168.371 15.747 1.00 48.99 ? 275 LYS A NZ 1 ATOM 1710 N N . GLY A 1 224 ? -18.255 171.856 15.091 1.00 16.07 ? 276 GLY A N 1 ATOM 1711 C CA . GLY A 1 224 ? -18.541 172.943 16.007 1.00 17.62 ? 276 GLY A CA 1 ATOM 1712 C C . GLY A 1 224 ? -19.707 172.554 16.899 1.00 18.84 ? 276 GLY A C 1 ATOM 1713 O O . GLY A 1 224 ? -20.323 171.504 16.722 1.00 19.85 ? 276 GLY A O 1 ATOM 1714 N N . GLN A 1 225 ? -20.019 173.421 17.851 1.00 19.70 ? 277 GLN A N 1 ATOM 1715 C CA . GLN A 1 225 ? -21.010 173.118 18.875 1.00 19.83 ? 277 GLN A CA 1 ATOM 1716 C C . GLN A 1 225 ? -22.442 173.376 18.435 1.00 23.78 ? 277 GLN A C 1 ATOM 1717 O O . GLN A 1 225 ? -23.381 172.953 19.105 1.00 22.67 ? 277 GLN A O 1 ATOM 1718 C CB . GLN A 1 225 ? -20.719 173.946 20.124 1.00 23.59 ? 277 GLN A CB 1 ATOM 1719 C CG . GLN A 1 225 ? -19.471 173.516 20.870 1.00 31.75 ? 277 GLN A CG 1 ATOM 1720 C CD . GLN A 1 225 ? -19.797 172.629 22.052 1.00 38.76 ? 277 GLN A CD 1 ATOM 1721 O OE1 . GLN A 1 225 ? -20.277 173.100 23.087 1.00 40.13 ? 277 GLN A OE1 1 ATOM 1722 N NE2 . GLN A 1 225 ? -19.556 171.334 21.898 1.00 36.83 ? 277 GLN A NE2 1 ATOM 1723 N N . THR A 1 226 ? -22.608 174.082 17.324 1.00 18.62 ? 278 THR A N 1 ATOM 1724 C CA . THR A 1 226 ? -23.941 174.468 16.866 1.00 19.53 ? 278 THR A CA 1 ATOM 1725 C C . THR A 1 226 ? -24.466 173.495 15.811 1.00 20.29 ? 278 THR A C 1 ATOM 1726 O O . THR A 1 226 ? -23.762 172.574 15.398 1.00 21.41 ? 278 THR A O 1 ATOM 1727 C CB . THR A 1 226 ? -23.936 175.904 16.295 1.00 18.96 ? 278 THR A CB 1 ATOM 1728 O OG1 . THR A 1 226 ? -23.584 175.884 14.904 1.00 19.65 ? 278 THR A OG1 1 ATOM 1729 C CG2 . THR A 1 226 ? -22.957 176.797 17.062 1.00 19.86 ? 278 THR A CG2 1 ATOM 1730 N N . SER A 1 227 ? -25.710 173.686 15.381 1.00 20.34 ? 279 SER A N 1 ATOM 1731 C CA . SER A 1 227 ? -26.296 172.808 14.376 1.00 21.40 ? 279 SER A CA 1 ATOM 1732 C C . SER A 1 227 ? -25.911 173.279 12.968 1.00 18.67 ? 279 SER A C 1 ATOM 1733 O O . SER A 1 227 ? -26.196 172.602 11.980 1.00 25.47 ? 279 SER A O 1 ATOM 1734 C CB . SER A 1 227 ? -27.822 172.743 14.535 1.00 26.85 ? 279 SER A CB 1 ATOM 1735 O OG . SER A 1 227 ? -28.400 174.023 14.405 1.00 35.65 ? 279 SER A OG 1 ATOM 1736 N N . HIS A 1 228 ? -25.253 174.433 12.883 1.00 21.91 ? 280 HIS A N 1 ATOM 1737 C CA . HIS A 1 228 ? -24.755 174.940 11.609 1.00 21.28 ? 280 HIS A CA 1 ATOM 1738 C C . HIS A 1 228 ? -23.340 174.390 11.418 1.00 19.80 ? 280 HIS A C 1 ATOM 1739 O O . HIS A 1 228 ? -22.376 174.927 11.968 1.00 20.14 ? 280 HIS A O 1 ATOM 1740 C CB . HIS A 1 228 ? -24.778 176.470 11.584 1.00 21.71 ? 280 HIS A CB 1 ATOM 1741 C CG . HIS A 1 228 ? -24.506 177.061 10.237 1.00 21.82 ? 280 HIS A CG 1 ATOM 1742 N ND1 . HIS A 1 228 ? -24.549 178.418 10.001 1.00 23.41 ? 280 HIS A ND1 1 ATOM 1743 C CD2 . HIS A 1 228 ? -24.181 176.483 9.056 1.00 25.61 ? 280 HIS A CD2 1 ATOM 1744 C CE1 . HIS A 1 228 ? -24.252 178.652 8.735 1.00 23.57 ? 280 HIS A CE1 1 ATOM 1745 N NE2 . HIS A 1 228 ? -24.034 177.493 8.137 1.00 24.19 ? 280 HIS A NE2 1 ATOM 1746 N N . VAL A 1 229 ? -23.242 173.309 10.653 1.00 19.45 ? 281 VAL A N 1 ATOM 1747 C CA . VAL A 1 229 ? -22.016 172.512 10.563 1.00 18.09 ? 281 VAL A CA 1 ATOM 1748 C C . VAL A 1 229 ? -20.818 173.326 10.087 1.00 18.85 ? 281 VAL A C 1 ATOM 1749 O O . VAL A 1 229 ? -20.829 173.909 9.002 1.00 16.70 ? 281 VAL A O 1 ATOM 1750 C CB . VAL A 1 229 ? -22.209 171.307 9.621 1.00 18.83 ? 281 VAL A CB 1 ATOM 1751 C CG1 . VAL A 1 229 ? -20.929 170.496 9.498 1.00 20.45 ? 281 VAL A CG1 1 ATOM 1752 C CG2 . VAL A 1 229 ? -23.327 170.422 10.127 1.00 23.50 ? 281 VAL A CG2 1 ATOM 1753 N N . GLY A 1 230 ? -19.772 173.343 10.908 1.00 17.72 ? 282 GLY A N 1 ATOM 1754 C CA . GLY A 1 230 ? -18.554 174.060 10.582 1.00 19.54 ? 282 GLY A CA 1 ATOM 1755 C C . GLY A 1 230 ? -18.403 175.387 11.292 1.00 18.41 ? 282 GLY A C 1 ATOM 1756 O O . GLY A 1 230 ? -17.356 176.020 11.200 1.00 19.28 ? 282 GLY A O 1 ATOM 1757 N N . CYS A 1 231 ? -19.436 175.815 12.010 1.00 17.77 ? 283 CYS A N 1 ATOM 1758 C CA . CYS A 1 231 ? -19.424 177.142 12.617 1.00 16.64 ? 283 CYS A CA 1 ATOM 1759 C C . CYS A 1 231 ? -18.920 177.160 14.058 1.00 15.07 ? 283 CYS A C 1 ATOM 1760 O O . CYS A 1 231 ? -19.051 176.169 14.778 1.00 17.47 ? 283 CYS A O 1 ATOM 1761 C CB . CYS A 1 231 ? -20.825 177.748 12.558 1.00 18.34 ? 283 CYS A CB 1 ATOM 1762 S SG . CYS A 1 231 ? -21.332 178.162 10.870 1.00 21.56 ? 283 CYS A SG 1 ATOM 1763 N N . PRO A 1 232 ? -18.334 178.293 14.486 1.00 14.79 ? 284 PRO A N 1 ATOM 1764 C CA . PRO A 1 232 ? -17.890 178.414 15.881 1.00 14.73 ? 284 PRO A CA 1 ATOM 1765 C C . PRO A 1 232 ? -19.061 178.481 16.852 1.00 19.28 ? 284 PRO A C 1 ATOM 1766 O O . PRO A 1 232 ? -20.168 178.819 16.435 1.00 17.96 ? 284 PRO A O 1 ATOM 1767 C CB . PRO A 1 232 ? -17.104 179.735 15.903 1.00 17.87 ? 284 PRO A CB 1 ATOM 1768 C CG . PRO A 1 232 ? -16.961 180.161 14.464 1.00 19.81 ? 284 PRO A CG 1 ATOM 1769 C CD . PRO A 1 232 ? -18.061 179.516 13.709 1.00 18.15 ? 284 PRO A CD 1 ATOM 1770 N N . PRO A 1 233 ? -18.820 178.192 18.138 1.00 18.10 ? 285 PRO A N 1 ATOM 1771 C CA . PRO A 1 233 ? -17.539 177.821 18.753 1.00 18.75 ? 285 PRO A CA 1 ATOM 1772 C C . PRO A 1 233 ? -17.195 176.344 18.596 1.00 18.56 ? 285 PRO A C 1 ATOM 1773 O O . PRO A 1 233 ? -18.040 175.547 18.194 1.00 17.90 ? 285 PRO A O 1 ATOM 1774 C CB . PRO A 1 233 ? -17.757 178.170 20.226 1.00 21.47 ? 285 PRO A CB 1 ATOM 1775 C CG . PRO A 1 233 ? -19.208 177.935 20.430 1.00 21.02 ? 285 PRO A CG 1 ATOM 1776 C CD . PRO A 1 233 ? -19.877 178.354 19.153 1.00 19.67 ? 285 PRO A CD 1 ATOM 1777 N N . TYR A 1 234 ? -15.954 175.996 18.922 1.00 17.08 ? 286 TYR A N 1 ATOM 1778 C CA . TYR A 1 234 ? -15.466 174.631 18.783 1.00 17.25 ? 286 TYR A CA 1 ATOM 1779 C C . TYR A 1 234 ? -15.069 174.085 20.142 1.00 16.60 ? 286 TYR A C 1 ATOM 1780 O O . TYR A 1 234 ? -14.792 174.848 21.068 1.00 20.20 ? 286 TYR A O 1 ATOM 1781 C CB . TYR A 1 234 ? -14.275 174.589 17.807 1.00 15.11 ? 286 TYR A CB 1 ATOM 1782 C CG . TYR A 1 234 ? -14.596 175.264 16.497 1.00 13.91 ? 286 TYR A CG 1 ATOM 1783 C CD1 . TYR A 1 234 ? -15.343 174.611 15.528 1.00 14.09 ? 286 TYR A CD1 1 ATOM 1784 C CD2 . TYR A 1 234 ? -14.184 176.566 16.244 1.00 15.05 ? 286 TYR A CD2 1 ATOM 1785 C CE1 . TYR A 1 234 ? -15.666 175.225 14.345 1.00 14.28 ? 286 TYR A CE1 1 ATOM 1786 C CE2 . TYR A 1 234 ? -14.493 177.188 15.059 1.00 13.76 ? 286 TYR A CE2 1 ATOM 1787 C CZ . TYR A 1 234 ? -15.242 176.514 14.114 1.00 13.92 ? 286 TYR A CZ 1 ATOM 1788 O OH . TYR A 1 234 ? -15.570 177.135 12.929 1.00 16.50 ? 286 TYR A OH 1 ATOM 1789 N N . ASN A 1 235 ? -15.052 172.763 20.259 1.00 15.37 ? 287 ASN A N 1 ATOM 1790 C CA . ASN A 1 235 ? -14.659 172.118 21.503 1.00 17.96 ? 287 ASN A CA 1 ATOM 1791 C C . ASN A 1 235 ? -13.838 170.880 21.196 1.00 16.14 ? 287 ASN A C 1 ATOM 1792 O O . ASN A 1 235 ? -14.267 169.760 21.438 1.00 16.73 ? 287 ASN A O 1 ATOM 1793 C CB . ASN A 1 235 ? -15.895 171.766 22.345 1.00 17.11 ? 287 ASN A CB 1 ATOM 1794 C CG . ASN A 1 235 ? -15.548 171.434 23.792 1.00 20.34 ? 287 ASN A CG 1 ATOM 1795 O OD1 . ASN A 1 235 ? -14.512 171.854 24.311 1.00 24.33 ? 287 ASN A OD1 1 ATOM 1796 N ND2 . ASN A 1 235 ? -16.421 170.681 24.451 1.00 24.18 ? 287 ASN A ND2 1 ATOM 1797 N N . PRO A 1 236 ? -12.638 171.087 20.635 1.00 17.22 ? 288 PRO A N 1 ATOM 1798 C CA . PRO A 1 236 ? -11.753 169.951 20.391 1.00 16.66 ? 288 PRO A CA 1 ATOM 1799 C C . PRO A 1 236 ? -11.272 169.363 21.717 1.00 17.89 ? 288 PRO A C 1 ATOM 1800 O O . PRO A 1 236 ? -11.361 170.040 22.745 1.00 20.26 ? 288 PRO A O 1 ATOM 1801 C CB . PRO A 1 236 ? -10.607 170.570 19.578 1.00 17.47 ? 288 PRO A CB 1 ATOM 1802 C CG . PRO A 1 236 ? -10.583 171.999 20.000 1.00 19.26 ? 288 PRO A CG 1 ATOM 1803 C CD . PRO A 1 236 ? -12.023 172.365 20.229 1.00 19.45 ? 288 PRO A CD 1 ATOM 1804 N N . PRO A 1 237 ? -10.766 168.125 21.706 1.00 19.29 ? 289 PRO A N 1 ATOM 1805 C CA . PRO A 1 237 ? -10.613 167.280 20.521 1.00 15.42 ? 289 PRO A CA 1 ATOM 1806 C C . PRO A 1 237 ? -11.898 166.551 20.141 1.00 18.56 ? 289 PRO A C 1 ATOM 1807 O O . PRO A 1 237 ? -12.749 166.290 20.993 1.00 18.99 ? 289 PRO A O 1 ATOM 1808 C CB . PRO A 1 237 ? -9.519 166.293 20.946 1.00 19.23 ? 289 PRO A CB 1 ATOM 1809 C CG . PRO A 1 237 ? -9.696 166.169 22.420 1.00 21.87 ? 289 PRO A CG 1 ATOM 1810 C CD . PRO A 1 237 ? -10.186 167.498 22.911 1.00 22.92 ? 289 PRO A CD 1 ATOM 1811 N N . HIS A 1 238 ? -12.025 166.248 18.855 1.00 16.18 ? 290 HIS A N 1 ATOM 1812 C CA . HIS A 1 238 ? -13.112 165.441 18.320 1.00 16.36 ? 290 HIS A CA 1 ATOM 1813 C C . HIS A 1 238 ? -12.567 164.076 17.924 1.00 19.33 ? 290 HIS A C 1 ATOM 1814 O O . HIS A 1 238 ? -11.494 164.001 17.326 1.00 21.76 ? 290 HIS A O 1 ATOM 1815 C CB . HIS A 1 238 ? -13.732 166.139 17.110 1.00 18.14 ? 290 HIS A CB 1 ATOM 1816 C CG . HIS A 1 238 ? -14.664 165.272 16.325 1.00 23.02 ? 290 HIS A CG 1 ATOM 1817 N ND1 . HIS A 1 238 ? -15.927 164.947 16.767 1.00 25.51 ? 290 HIS A ND1 1 ATOM 1818 C CD2 . HIS A 1 238 ? -14.515 164.663 15.125 1.00 25.07 ? 290 HIS A CD2 1 ATOM 1819 C CE1 . HIS A 1 238 ? -16.517 164.173 15.873 1.00 27.19 ? 290 HIS A CE1 1 ATOM 1820 N NE2 . HIS A 1 238 ? -15.681 163.986 14.867 1.00 25.45 ? 290 HIS A NE2 1 ATOM 1821 N N . VAL A 1 239 ? -13.275 162.997 18.246 1.00 17.05 ? 291 VAL A N 1 ATOM 1822 C CA . VAL A 1 239 ? -12.777 161.667 17.907 1.00 16.02 ? 291 VAL A CA 1 ATOM 1823 C C . VAL A 1 239 ? -13.128 161.352 16.460 1.00 19.40 ? 291 VAL A C 1 ATOM 1824 O O . VAL A 1 239 ? -14.295 161.396 16.068 1.00 17.81 ? 291 VAL A O 1 ATOM 1825 C CB . VAL A 1 239 ? -13.343 160.567 18.822 1.00 18.85 ? 291 VAL A CB 1 ATOM 1826 C CG1 . VAL A 1 239 ? -12.765 159.207 18.447 1.00 20.63 ? 291 VAL A CG1 1 ATOM 1827 C CG2 . VAL A 1 239 ? -13.030 160.876 20.272 1.00 28.50 ? 291 VAL A CG2 1 ATOM 1828 N N . THR A 1 240 ? -12.112 161.039 15.663 1.00 16.19 ? 292 THR A N 1 ATOM 1829 C CA . THR A 1 240 ? -12.317 160.817 14.242 1.00 16.31 ? 292 THR A CA 1 ATOM 1830 C C . THR A 1 240 ? -13.040 159.506 13.954 1.00 16.07 ? 292 THR A C 1 ATOM 1831 O O . THR A 1 240 ? -13.023 158.557 14.750 1.00 16.77 ? 292 THR A O 1 ATOM 1832 C CB . THR A 1 240 ? -10.988 160.797 13.472 1.00 13.90 ? 292 THR A CB 1 ATOM 1833 O OG1 . THR A 1 240 ? -10.205 159.681 13.910 1.00 14.21 ? 292 THR A OG1 1 ATOM 1834 C CG2 . THR A 1 240 ? -10.205 162.082 13.689 1.00 16.76 ? 292 THR A CG2 1 ATOM 1835 N N . LYS A 1 241 ? -13.679 159.476 12.793 1.00 17.84 ? 293 LYS A N 1 ATOM 1836 C CA . LYS A 1 241 ? -14.240 158.256 12.240 1.00 16.43 ? 293 LYS A CA 1 ATOM 1837 C C . LYS A 1 241 ? -13.305 157.711 11.172 1.00 15.63 ? 293 LYS A C 1 ATOM 1838 O O . LYS A 1 241 ? -12.296 158.336 10.845 1.00 16.39 ? 293 LYS A O 1 ATOM 1839 C CB . LYS A 1 241 ? -15.617 158.523 11.642 1.00 18.53 ? 293 LYS A CB 1 ATOM 1840 C CG . LYS A 1 241 ? -16.637 159.035 12.637 1.00 27.90 ? 293 LYS A CG 1 ATOM 1841 C CD . LYS A 1 241 ? -17.059 157.960 13.621 1.00 29.95 ? 293 LYS A CD 1 ATOM 1842 C CE . LYS A 1 241 ? -18.281 158.407 14.408 1.00 39.82 ? 293 LYS A CE 1 ATOM 1843 N NZ . LYS A 1 241 ? -18.153 159.819 14.877 1.00 48.13 ? 293 LYS A NZ 1 ATOM 1844 N N . GLY A 1 242 ? -13.645 156.551 10.623 1.00 17.00 ? 294 GLY A N 1 ATOM 1845 C CA . GLY A 1 242 ? -12.828 155.931 9.594 1.00 18.95 ? 294 GLY A CA 1 ATOM 1846 C C . GLY A 1 242 ? -13.313 156.230 8.188 1.00 16.35 ? 294 GLY A C 1 ATOM 1847 O O . GLY A 1 242 ? -14.415 156.745 8.002 1.00 16.32 ? 294 GLY A O 1 ATOM 1848 N N . MET A 1 243 ? -12.492 155.902 7.192 1.00 16.62 ? 295 MET A N 1 ATOM 1849 C CA . MET A 1 243 ? -12.911 155.986 5.795 1.00 17.53 ? 295 MET A CA 1 ATOM 1850 C C . MET A 1 243 ? -14.143 155.129 5.561 1.00 16.24 ? 295 MET A C 1 ATOM 1851 O O . MET A 1 243 ? -14.302 154.083 6.183 1.00 17.87 ? 295 MET A O 1 ATOM 1852 C CB . MET A 1 243 ? -11.808 155.515 4.848 1.00 18.92 ? 295 MET A CB 1 ATOM 1853 C CG . MET A 1 243 ? -10.501 156.287 4.939 1.00 17.35 ? 295 MET A CG 1 ATOM 1854 S SD . MET A 1 243 ? -9.225 155.529 3.915 1.00 19.01 ? 295 MET A SD 1 ATOM 1855 C CE . MET A 1 243 ? -9.796 155.984 2.288 1.00 20.96 ? 295 MET A CE 1 ATOM 1856 N N . LYS A 1 244 ? -14.990 155.571 4.645 1.00 17.67 ? 296 LYS A N 1 ATOM 1857 C CA . LYS A 1 244 ? -16.146 154.777 4.255 1.00 15.54 ? 296 LYS A CA 1 ATOM 1858 C C . LYS A 1 244 ? -15.691 153.451 3.644 1.00 21.54 ? 296 LYS A C 1 ATOM 1859 O O . LYS A 1 244 ? -16.289 152.407 3.908 1.00 20.15 ? 296 LYS A O 1 ATOM 1860 C CB . LYS A 1 244 ? -17.019 155.550 3.273 1.00 20.41 ? 296 LYS A CB 1 ATOM 1861 C CG . LYS A 1 244 ? -18.301 154.833 2.880 1.00 21.13 ? 296 LYS A CG 1 ATOM 1862 C CD . LYS A 1 244 ? -19.162 155.731 2.013 1.00 27.65 ? 296 LYS A CD 1 ATOM 1863 C CE . LYS A 1 244 ? -20.399 155.021 1.498 1.00 29.56 ? 296 LYS A CE 1 ATOM 1864 N NZ . LYS A 1 244 ? -21.167 155.913 0.584 1.00 37.76 ? 296 LYS A NZ 1 ATOM 1865 N N . ASP A 1 245 ? -14.633 153.491 2.836 1.00 17.16 ? 297 ASP A N 1 ATOM 1866 C CA . ASP A 1 245 ? -14.105 152.278 2.207 1.00 20.53 ? 297 ASP A CA 1 ATOM 1867 C C . ASP A 1 245 ? -12.585 152.299 2.105 1.00 21.81 ? 297 ASP A C 1 ATOM 1868 O O . ASP A 1 245 ? -12.021 152.960 1.235 1.00 20.27 ? 297 ASP A O 1 ATOM 1869 C CB . ASP A 1 245 ? -14.704 152.090 0.812 1.00 23.06 ? 297 ASP A CB 1 ATOM 1870 C CG . ASP A 1 245 ? -14.202 150.829 0.127 1.00 28.77 ? 297 ASP A CG 1 ATOM 1871 O OD1 . ASP A 1 245 ? -13.727 149.911 0.831 1.00 23.36 ? 297 ASP A OD1 1 ATOM 1872 O OD2 . ASP A 1 245 ? -14.289 150.757 -1.116 1.00 36.69 ? 297 ASP A OD2 1 ATOM 1873 N N . SER A 1 246 ? -11.936 151.553 2.991 1.00 20.97 ? 298 SER A N 1 ATOM 1874 C CA . SER A 1 246 ? -10.484 151.432 2.980 1.00 25.49 ? 298 SER A CA 1 ATOM 1875 C C . SER A 1 246 ? -10.044 150.082 2.409 1.00 26.66 ? 298 SER A C 1 ATOM 1876 O O . SER A 1 246 ? -8.858 149.769 2.395 1.00 20.78 ? 298 SER A O 1 ATOM 1877 C CB . SER A 1 246 ? -9.935 151.610 4.398 1.00 27.59 ? 298 SER A CB 1 ATOM 1878 O OG . SER A 1 246 ? -8.516 151.595 4.404 1.00 35.25 ? 298 SER A OG 1 ATOM 1879 N N . SER A 1 247 ? -10.995 149.287 1.922 1.00 23.39 ? 299 SER A N 1 ATOM 1880 C CA . SER A 1 247 ? -10.712 147.895 1.573 1.00 20.74 ? 299 SER A CA 1 ATOM 1881 C C . SER A 1 247 ? -9.699 147.720 0.438 1.00 19.74 ? 299 SER A C 1 ATOM 1882 O O . SER A 1 247 ? -9.041 146.681 0.359 1.00 23.04 ? 299 SER A O 1 ATOM 1883 C CB . SER A 1 247 ? -12.017 147.169 1.206 1.00 23.32 ? 299 SER A CB 1 ATOM 1884 O OG . SER A 1 247 ? -12.549 147.648 -0.013 1.00 25.00 ? 299 SER A OG 1 ATOM 1885 N N . TRP A 1 248 ? -9.562 148.723 -0.429 1.00 19.31 ? 300 TRP A N 1 ATOM 1886 C CA . TRP A 1 248 ? -8.636 148.639 -1.558 1.00 17.71 ? 300 TRP A CA 1 ATOM 1887 C C . TRP A 1 248 ? -7.202 148.953 -1.134 1.00 17.65 ? 300 TRP A C 1 ATOM 1888 O O . TRP A 1 248 ? -6.258 148.723 -1.893 1.00 20.54 ? 300 TRP A O 1 ATOM 1889 C CB . TRP A 1 248 ? -9.067 149.586 -2.685 1.00 21.68 ? 300 TRP A CB 1 ATOM 1890 C CG . TRP A 1 248 ? -9.094 151.052 -2.315 1.00 18.66 ? 300 TRP A CG 1 ATOM 1891 C CD1 . TRP A 1 248 ? -10.154 151.757 -1.822 1.00 21.10 ? 300 TRP A CD1 1 ATOM 1892 C CD2 . TRP A 1 248 ? -8.007 151.987 -2.422 1.00 15.96 ? 300 TRP A CD2 1 ATOM 1893 N NE1 . TRP A 1 248 ? -9.796 153.070 -1.615 1.00 20.04 ? 300 TRP A NE1 1 ATOM 1894 C CE2 . TRP A 1 248 ? -8.484 153.235 -1.973 1.00 19.01 ? 300 TRP A CE2 1 ATOM 1895 C CE3 . TRP A 1 248 ? -6.683 151.888 -2.856 1.00 21.18 ? 300 TRP A CE3 1 ATOM 1896 C CZ2 . TRP A 1 248 ? -7.683 154.373 -1.942 1.00 18.77 ? 300 TRP A CZ2 1 ATOM 1897 C CZ3 . TRP A 1 248 ? -5.887 153.019 -2.823 1.00 17.70 ? 300 TRP A CZ3 1 ATOM 1898 C CH2 . TRP A 1 248 ? -6.387 154.244 -2.369 1.00 17.34 ? 300 TRP A CH2 1 ATOM 1899 N N . ILE A 1 249 ? -7.039 149.460 0.083 1.00 19.36 ? 301 ILE A N 1 ATOM 1900 C CA . ILE A 1 249 ? -5.712 149.821 0.580 1.00 17.99 ? 301 ILE A CA 1 ATOM 1901 C C . ILE A 1 249 ? -5.096 148.610 1.269 1.00 16.98 ? 301 ILE A C 1 ATOM 1902 O O . ILE A 1 249 ? -5.197 148.440 2.480 1.00 20.78 ? 301 ILE A O 1 ATOM 1903 C CB . ILE A 1 249 ? -5.768 151.024 1.538 1.00 15.33 ? 301 ILE A CB 1 ATOM 1904 C CG1 . ILE A 1 249 ? -6.485 152.200 0.868 1.00 18.88 ? 301 ILE A CG1 1 ATOM 1905 C CG2 . ILE A 1 249 ? -4.344 151.438 1.927 1.00 17.98 ? 301 ILE A CG2 1 ATOM 1906 C CD1 . ILE A 1 249 ? -6.632 153.446 1.743 1.00 19.11 ? 301 ILE A CD1 1 ATOM 1907 N N . THR A 1 250 ? -4.443 147.776 0.471 1.00 18.46 ? 302 THR A N 1 ATOM 1908 C CA . THR A 1 250 ? -3.996 146.466 0.929 1.00 18.84 ? 302 THR A CA 1 ATOM 1909 C C . THR A 1 250 ? -2.529 146.435 1.353 1.00 20.34 ? 302 THR A C 1 ATOM 1910 O O . THR A 1 250 ? -2.077 145.461 1.950 1.00 21.73 ? 302 THR A O 1 ATOM 1911 C CB . THR A 1 250 ? -4.210 145.403 -0.169 1.00 22.03 ? 302 THR A CB 1 ATOM 1912 O OG1 . THR A 1 250 ? -3.542 145.803 -1.371 1.00 25.01 ? 302 THR A OG1 1 ATOM 1913 C CG2 . THR A 1 250 ? -5.692 145.236 -0.465 1.00 28.01 ? 302 THR A CG2 1 ATOM 1914 N N . GLY A 1 251 ? -1.790 147.499 1.059 1.00 17.03 ? 303 GLY A N 1 ATOM 1915 C CA . GLY A 1 251 ? -0.369 147.525 1.348 1.00 15.38 ? 303 GLY A CA 1 ATOM 1916 C C . GLY A 1 251 ? 0.166 148.935 1.291 1.00 14.99 ? 303 GLY A C 1 ATOM 1917 O O . GLY A 1 251 ? -0.569 149.866 0.986 1.00 14.87 ? 303 GLY A O 1 ATOM 1918 N N . PRO A 1 252 ? 1.461 149.099 1.586 1.00 13.54 ? 304 PRO A N 1 ATOM 1919 C CA . PRO A 1 252 ? 2.034 150.449 1.634 1.00 14.44 ? 304 PRO A CA 1 ATOM 1920 C C . PRO A 1 252 ? 1.927 151.215 0.318 1.00 13.66 ? 304 PRO A C 1 ATOM 1921 O O . PRO A 1 252 ? 1.726 152.423 0.368 1.00 14.54 ? 304 PRO A O 1 ATOM 1922 C CB . PRO A 1 252 ? 3.500 150.205 2.014 1.00 17.52 ? 304 PRO A CB 1 ATOM 1923 C CG . PRO A 1 252 ? 3.728 148.741 1.944 1.00 19.19 ? 304 PRO A CG 1 ATOM 1924 C CD . PRO A 1 252 ? 2.399 148.071 2.063 1.00 16.21 ? 304 PRO A CD 1 ATOM 1925 N N . PHE A 1 253 ? 2.051 150.570 -0.839 1.00 14.83 ? 305 PHE A N 1 ATOM 1926 C CA . PHE A 1 253 ? 1.941 151.327 -2.080 1.00 13.79 ? 305 PHE A CA 1 ATOM 1927 C C . PHE A 1 253 ? 0.525 151.871 -2.278 1.00 14.18 ? 305 PHE A C 1 ATOM 1928 O O . PHE A 1 253 ? 0.344 153.010 -2.710 1.00 14.21 ? 305 PHE A O 1 ATOM 1929 C CB . PHE A 1 253 ? 2.342 150.492 -3.293 1.00 17.72 ? 305 PHE A CB 1 ATOM 1930 C CG . PHE A 1 253 ? 2.081 151.191 -4.596 1.00 16.80 ? 305 PHE A CG 1 ATOM 1931 C CD1 . PHE A 1 253 ? 2.794 152.328 -4.944 1.00 16.38 ? 305 PHE A CD1 1 ATOM 1932 C CD2 . PHE A 1 253 ? 1.086 150.743 -5.451 1.00 17.92 ? 305 PHE A CD2 1 ATOM 1933 C CE1 . PHE A 1 253 ? 2.538 152.989 -6.120 1.00 14.36 ? 305 PHE A CE1 1 ATOM 1934 C CE2 . PHE A 1 253 ? 0.829 151.399 -6.636 1.00 19.87 ? 305 PHE A CE2 1 ATOM 1935 C CZ . PHE A 1 253 ? 1.551 152.527 -6.974 1.00 18.69 ? 305 PHE A CZ 1 ATOM 1936 N N . GLU A 1 254 ? -0.484 151.066 -1.965 1.00 15.48 ? 306 GLU A N 1 ATOM 1937 C CA . GLU A 1 254 ? -1.854 151.538 -2.073 1.00 16.04 ? 306 GLU A CA 1 ATOM 1938 C C . GLU A 1 254 ? -2.095 152.719 -1.128 1.00 14.96 ? 306 GLU A C 1 ATOM 1939 O O . GLU A 1 254 ? -2.831 153.644 -1.451 1.00 15.82 ? 306 GLU A O 1 ATOM 1940 C CB . GLU A 1 254 ? -2.824 150.395 -1.792 1.00 16.51 ? 306 GLU A CB 1 ATOM 1941 C CG . GLU A 1 254 ? -2.845 149.331 -2.899 1.00 23.68 ? 306 GLU A CG 1 ATOM 1942 C CD . GLU A 1 254 ? -1.643 148.391 -2.878 1.00 28.11 ? 306 GLU A CD 1 ATOM 1943 O OE1 . GLU A 1 254 ? -0.927 148.329 -1.855 1.00 21.05 ? 306 GLU A OE1 1 ATOM 1944 O OE2 . GLU A 1 254 ? -1.416 147.704 -3.899 1.00 32.95 ? 306 GLU A OE2 1 ATOM 1945 N N . CYS A 1 255 ? -1.435 152.704 0.025 1.00 14.71 ? 307 CYS A N 1 ATOM 1946 C CA . CYS A 1 255 ? -1.529 153.819 0.958 1.00 14.99 ? 307 CYS A CA 1 ATOM 1947 C C . CYS A 1 255 ? -0.958 155.091 0.320 1.00 14.49 ? 307 CYS A C 1 ATOM 1948 O O . CYS A 1 255 ? -1.533 156.173 0.463 1.00 14.74 ? 307 CYS A O 1 ATOM 1949 C CB . CYS A 1 255 ? -0.801 153.462 2.255 1.00 17.56 ? 307 CYS A CB 1 ATOM 1950 S SG . CYS A 1 255 ? -0.955 154.684 3.574 1.00 19.32 ? 307 CYS A SG 1 ATOM 1951 N N . SER A 1 256 ? 0.155 154.970 -0.405 1.00 12.40 ? 308 SER A N 1 ATOM 1952 C CA . SER A 1 256 ? 0.731 156.133 -1.097 1.00 13.10 ? 308 SER A CA 1 ATOM 1953 C C . SER A 1 256 ? -0.240 156.702 -2.144 1.00 13.96 ? 308 SER A C 1 ATOM 1954 O O . SER A 1 256 ? -0.266 157.913 -2.371 1.00 13.84 ? 308 SER A O 1 ATOM 1955 C CB . SER A 1 256 ? 2.078 155.785 -1.755 1.00 15.52 ? 308 SER A CB 1 ATOM 1956 O OG . SER A 1 256 ? 1.935 155.051 -2.967 1.00 14.54 ? 308 SER A OG 1 ATOM 1957 N N . ILE A 1 257 ? -1.047 155.839 -2.765 1.00 14.47 ? 309 ILE A N 1 ATOM 1958 C CA . ILE A 1 257 ? -2.006 156.297 -3.763 1.00 14.05 ? 309 ILE A CA 1 ATOM 1959 C C . ILE A 1 257 ? -3.055 157.189 -3.107 1.00 10.48 ? 309 ILE A C 1 ATOM 1960 O O . ILE A 1 257 ? -3.490 158.182 -3.696 1.00 14.32 ? 309 ILE A O 1 ATOM 1961 C CB . ILE A 1 257 ? -2.695 155.107 -4.483 1.00 11.96 ? 309 ILE A CB 1 ATOM 1962 C CG1 . ILE A 1 257 ? -1.698 154.410 -5.420 1.00 15.92 ? 309 ILE A CG1 1 ATOM 1963 C CG2 . ILE A 1 257 ? -3.939 155.572 -5.271 1.00 16.80 ? 309 ILE A CG2 1 ATOM 1964 C CD1 . ILE A 1 257 ? -2.232 153.131 -6.070 1.00 19.07 ? 309 ILE A CD1 1 ATOM 1965 N N . LEU A 1 258 ? -3.479 156.843 -1.893 1.00 13.45 ? 310 LEU A N 1 ATOM 1966 C CA . LEU A 1 258 ? -4.421 157.697 -1.181 1.00 12.23 ? 310 LEU A CA 1 ATOM 1967 C C . LEU A 1 258 ? -3.849 159.108 -1.048 1.00 13.74 ? 310 LEU A C 1 ATOM 1968 O O . LEU A 1 258 ? -4.551 160.088 -1.264 1.00 13.01 ? 310 LEU A O 1 ATOM 1969 C CB . LEU A 1 258 ? -4.765 157.122 0.200 1.00 15.15 ? 310 LEU A CB 1 ATOM 1970 C CG . LEU A 1 258 ? -5.762 157.946 1.025 1.00 13.74 ? 310 LEU A CG 1 ATOM 1971 C CD1 . LEU A 1 258 ? -7.106 158.091 0.299 1.00 17.10 ? 310 LEU A CD1 1 ATOM 1972 C CD2 . LEU A 1 258 ? -5.966 157.330 2.402 1.00 14.12 ? 310 LEU A CD2 1 ATOM 1973 N N . SER A 1 259 ? -2.562 159.219 -0.727 1.00 13.02 ? 311 SER A N 1 ATOM 1974 C CA . SER A 1 259 ? -1.925 160.532 -0.663 1.00 12.02 ? 311 SER A CA 1 ATOM 1975 C C . SER A 1 259 ? -1.853 161.228 -2.014 1.00 12.49 ? 311 SER A C 1 ATOM 1976 O O . SER A 1 259 ? -2.216 162.396 -2.142 1.00 14.64 ? 311 SER A O 1 ATOM 1977 C CB . SER A 1 259 ? -0.509 160.423 -0.094 1.00 13.95 ? 311 SER A CB 1 ATOM 1978 O OG . SER A 1 259 ? 0.208 161.619 -0.393 1.00 13.67 ? 311 SER A OG 1 ATOM 1979 N N . ARG A 1 260 ? -1.369 160.506 -3.020 1.00 12.32 ? 312 ARG A N 1 ATOM 1980 C CA . ARG A 1 260 ? -1.229 161.052 -4.365 1.00 11.60 ? 312 ARG A CA 1 ATOM 1981 C C . ARG A 1 260 ? -2.509 161.735 -4.826 1.00 12.18 ? 312 ARG A C 1 ATOM 1982 O O . ARG A 1 260 ? -2.491 162.823 -5.405 1.00 14.86 ? 312 ARG A O 1 ATOM 1983 C CB . ARG A 1 260 ? -0.863 159.930 -5.340 1.00 13.52 ? 312 ARG A CB 1 ATOM 1984 C CG . ARG A 1 260 ? -0.802 160.368 -6.782 1.00 14.49 ? 312 ARG A CG 1 ATOM 1985 C CD . ARG A 1 260 ? -0.494 159.214 -7.703 1.00 16.40 ? 312 ARG A CD 1 ATOM 1986 N NE . ARG A 1 260 ? -0.536 159.640 -9.089 1.00 14.60 ? 312 ARG A NE 1 ATOM 1987 C CZ . ARG A 1 260 ? -0.317 158.837 -10.126 1.00 16.62 ? 312 ARG A CZ 1 ATOM 1988 N NH1 . ARG A 1 260 ? -0.056 157.555 -9.932 1.00 16.03 ? 312 ARG A NH1 1 ATOM 1989 N NH2 . ARG A 1 260 ? -0.366 159.325 -11.358 1.00 17.94 ? 312 ARG A NH2 1 ATOM 1990 N N . CYS A 1 261 ? -3.627 161.084 -4.547 1.00 14.53 ? 313 CYS A N 1 ATOM 1991 C CA . CYS A 1 261 ? -4.891 161.470 -5.160 1.00 14.39 ? 313 CYS A CA 1 ATOM 1992 C C . CYS A 1 261 ? -5.669 162.541 -4.399 1.00 18.92 ? 313 CYS A C 1 ATOM 1993 O O . CYS A 1 261 ? -6.617 163.106 -4.946 1.00 16.55 ? 313 CYS A O 1 ATOM 1994 C CB . CYS A 1 261 ? -5.780 160.237 -5.324 1.00 13.50 ? 313 CYS A CB 1 ATOM 1995 S SG . CYS A 1 261 ? -5.110 158.990 -6.433 1.00 17.12 ? 313 CYS A SG 1 ATOM 1996 N N . THR A 1 262 ? -5.290 162.825 -3.155 1.00 15.46 ? 314 THR A N 1 ATOM 1997 C CA . THR A 1 262 ? -6.108 163.695 -2.303 1.00 12.83 ? 314 THR A CA 1 ATOM 1998 C C . THR A 1 262 ? -5.530 165.090 -2.044 1.00 13.82 ? 314 THR A C 1 ATOM 1999 O O . THR A 1 262 ? -6.114 165.858 -1.290 1.00 14.70 ? 314 THR A O 1 ATOM 2000 C CB . THR A 1 262 ? -6.379 163.041 -0.927 1.00 12.39 ? 314 THR A CB 1 ATOM 2001 O OG1 . THR A 1 262 ? -5.144 162.636 -0.313 1.00 14.90 ? 314 THR A OG1 1 ATOM 2002 C CG2 . THR A 1 262 ? -7.284 161.833 -1.081 1.00 15.86 ? 314 THR A CG2 1 ATOM 2003 N N . THR A 1 263 ? -4.403 165.426 -2.670 1.00 13.55 ? 315 THR A N 1 ATOM 2004 C CA . THR A 1 263 ? -3.811 166.756 -2.535 1.00 12.84 ? 315 THR A CA 1 ATOM 2005 C C . THR A 1 263 ? -4.823 167.896 -2.664 1.00 14.71 ? 315 THR A C 1 ATOM 2006 O O . THR A 1 263 ? -4.863 168.802 -1.828 1.00 14.58 ? 315 THR A O 1 ATOM 2007 C CB . THR A 1 263 ? -2.698 166.948 -3.591 1.00 12.82 ? 315 THR A CB 1 ATOM 2008 O OG1 . THR A 1 263 ? -1.574 166.124 -3.241 1.00 14.60 ? 315 THR A OG1 1 ATOM 2009 C CG2 . THR A 1 263 ? -2.253 168.411 -3.713 1.00 15.93 ? 315 THR A CG2 1 ATOM 2010 N N . HIS A 1 264 ? -5.650 167.856 -3.702 1.00 15.22 ? 316 HIS A N 1 ATOM 2011 C CA . HIS A 1 264 ? -6.518 168.998 -3.981 1.00 12.90 ? 316 HIS A CA 1 ATOM 2012 C C . HIS A 1 264 ? -7.775 169.029 -3.122 1.00 14.29 ? 316 HIS A C 1 ATOM 2013 O O . HIS A 1 264 ? -8.582 169.947 -3.241 1.00 15.52 ? 316 HIS A O 1 ATOM 2014 C CB . HIS A 1 264 ? -6.885 169.025 -5.462 1.00 15.21 ? 316 HIS A CB 1 ATOM 2015 C CG . HIS A 1 264 ? -5.703 169.271 -6.339 1.00 14.93 ? 316 HIS A CG 1 ATOM 2016 N ND1 . HIS A 1 264 ? -4.966 170.432 -6.268 1.00 16.69 ? 316 HIS A ND1 1 ATOM 2017 C CD2 . HIS A 1 264 ? -5.099 168.493 -7.266 1.00 15.73 ? 316 HIS A CD2 1 ATOM 2018 C CE1 . HIS A 1 264 ? -3.963 170.365 -7.125 1.00 15.70 ? 316 HIS A CE1 1 ATOM 2019 N NE2 . HIS A 1 264 ? -4.023 169.200 -7.744 1.00 14.72 ? 316 HIS A NE2 1 ATOM 2020 N N . CYS A 1 265 ? -7.928 168.038 -2.252 1.00 14.48 ? 317 CYS A N 1 ATOM 2021 C CA . CYS A 1 265 ? -9.016 168.022 -1.280 1.00 13.52 ? 317 CYS A CA 1 ATOM 2022 C C . CYS A 1 265 ? -8.794 169.023 -0.154 1.00 14.60 ? 317 CYS A C 1 ATOM 2023 O O . CYS A 1 265 ? -9.727 169.349 0.572 1.00 16.02 ? 317 CYS A O 1 ATOM 2024 C CB . CYS A 1 265 ? -9.175 166.628 -0.679 1.00 13.76 ? 317 CYS A CB 1 ATOM 2025 S SG . CYS A 1 265 ? -9.423 165.300 -1.881 1.00 16.30 ? 317 CYS A SG 1 ATOM 2026 N N . TRP A 1 266 ? -7.556 169.490 0.002 1.00 15.53 ? 318 TRP A N 1 ATOM 2027 C CA . TRP A 1 266 ? -7.214 170.398 1.090 1.00 13.97 ? 318 TRP A CA 1 ATOM 2028 C C . TRP A 1 266 ? -7.179 171.829 0.596 1.00 13.38 ? 318 TRP A C 1 ATOM 2029 O O . TRP A 1 266 ? -6.783 172.091 -0.541 1.00 16.65 ? 318 TRP A O 1 ATOM 2030 C CB . TRP A 1 266 ? -5.862 170.031 1.707 1.00 12.63 ? 318 TRP A CB 1 ATOM 2031 C CG . TRP A 1 266 ? -5.742 168.586 2.000 1.00 13.52 ? 318 TRP A CG 1 ATOM 2032 C CD1 . TRP A 1 266 ? -4.873 167.712 1.424 1.00 14.26 ? 318 TRP A CD1 1 ATOM 2033 C CD2 . TRP A 1 266 ? -6.520 167.825 2.933 1.00 12.07 ? 318 TRP A CD2 1 ATOM 2034 N NE1 . TRP A 1 266 ? -5.053 166.456 1.941 1.00 13.73 ? 318 TRP A NE1 1 ATOM 2035 C CE2 . TRP A 1 266 ? -6.059 166.496 2.870 1.00 12.28 ? 318 TRP A CE2 1 ATOM 2036 C CE3 . TRP A 1 266 ? -7.557 168.137 3.819 1.00 13.68 ? 318 TRP A CE3 1 ATOM 2037 C CZ2 . TRP A 1 266 ? -6.598 165.477 3.660 1.00 12.26 ? 318 TRP A CZ2 1 ATOM 2038 C CZ3 . TRP A 1 266 ? -8.091 167.121 4.604 1.00 12.42 ? 318 TRP A CZ3 1 ATOM 2039 C CH2 . TRP A 1 266 ? -7.612 165.812 4.519 1.00 12.13 ? 318 TRP A CH2 1 ATOM 2040 N N . PRO A 1 267 ? -7.578 172.776 1.452 1.00 12.74 ? 319 PRO A N 1 ATOM 2041 C CA . PRO A 1 267 ? -7.596 174.170 1.015 1.00 14.68 ? 319 PRO A CA 1 ATOM 2042 C C . PRO A 1 267 ? -6.209 174.796 1.018 1.00 16.33 ? 319 PRO A C 1 ATOM 2043 O O . PRO A 1 267 ? -5.409 174.517 1.918 1.00 16.13 ? 319 PRO A O 1 ATOM 2044 C CB . PRO A 1 267 ? -8.489 174.841 2.052 1.00 15.85 ? 319 PRO A CB 1 ATOM 2045 C CG . PRO A 1 267 ? -8.243 174.068 3.287 1.00 14.22 ? 319 PRO A CG 1 ATOM 2046 C CD . PRO A 1 267 ? -8.018 172.639 2.853 1.00 14.63 ? 319 PRO A CD 1 ATOM 2047 N N . TYR A 1 268 ? -5.931 175.619 0.014 1.00 14.74 ? 320 TYR A N 1 ATOM 2048 C CA . TYR A 1 268 ? -4.756 176.474 0.026 1.00 15.38 ? 320 TYR A CA 1 ATOM 2049 C C . TYR A 1 268 ? -5.117 177.901 -0.359 1.00 18.52 ? 320 TYR A C 1 ATOM 2050 O O . TYR A 1 268 ? -5.763 178.137 -1.381 1.00 17.63 ? 320 TYR A O 1 ATOM 2051 C CB . TYR A 1 268 ? -3.663 175.970 -0.924 1.00 16.12 ? 320 TYR A CB 1 ATOM 2052 C CG . TYR A 1 268 ? -2.562 176.998 -1.049 1.00 16.19 ? 320 TYR A CG 1 ATOM 2053 C CD1 . TYR A 1 268 ? -1.714 177.262 0.021 1.00 15.98 ? 320 TYR A CD1 1 ATOM 2054 C CD2 . TYR A 1 268 ? -2.409 177.747 -2.207 1.00 16.38 ? 320 TYR A CD2 1 ATOM 2055 C CE1 . TYR A 1 268 ? -0.731 178.221 -0.071 1.00 16.70 ? 320 TYR A CE1 1 ATOM 2056 C CE2 . TYR A 1 268 ? -1.424 178.714 -2.304 1.00 17.93 ? 320 TYR A CE2 1 ATOM 2057 C CZ . TYR A 1 268 ? -0.587 178.940 -1.233 1.00 18.76 ? 320 TYR A CZ 1 ATOM 2058 O OH . TYR A 1 268 ? 0.393 179.898 -1.314 1.00 24.50 ? 320 TYR A OH 1 ATOM 2059 N N . LYS A 1 269 ? -4.681 178.841 0.471 1.00 17.25 ? 321 LYS A N 1 ATOM 2060 C CA . LYS A 1 269 ? -4.781 180.266 0.176 1.00 20.09 ? 321 LYS A CA 1 ATOM 2061 C C . LYS A 1 269 ? -3.429 180.900 0.465 1.00 21.27 ? 321 LYS A C 1 ATOM 2062 O O . LYS A 1 269 ? -2.767 180.535 1.442 1.00 21.21 ? 321 LYS A O 1 ATOM 2063 C CB . LYS A 1 269 ? -5.887 180.910 1.005 1.00 24.65 ? 321 LYS A CB 1 ATOM 2064 C CG . LYS A 1 269 ? -6.083 182.386 0.763 1.00 29.08 ? 321 LYS A CG 1 ATOM 2065 C CD . LYS A 1 269 ? -7.338 182.833 1.484 1.00 39.44 ? 321 LYS A CD 1 ATOM 2066 C CE . LYS A 1 269 ? -7.649 184.297 1.254 1.00 54.52 ? 321 LYS A CE 1 ATOM 2067 N NZ . LYS A 1 269 ? -8.998 184.642 1.785 1.00 59.01 ? 321 LYS A NZ 1 ATOM 2068 N N . SER A 1 270 ? -3.031 181.834 -0.397 1.00 23.31 ? 322 SER A N 1 ATOM 2069 C CA . SER A 1 270 ? -1.707 182.453 -0.353 1.00 23.90 ? 322 SER A CA 1 ATOM 2070 C C . SER A 1 270 ? -1.304 182.808 1.072 1.00 23.03 ? 322 SER A C 1 ATOM 2071 O O . SER A 1 270 ? -2.066 183.432 1.807 1.00 25.40 ? 322 SER A O 1 ATOM 2072 C CB . SER A 1 270 ? -1.682 183.706 -1.238 1.00 27.34 ? 322 SER A CB 1 ATOM 2073 O OG . SER A 1 270 ? -0.356 184.068 -1.577 1.00 37.42 ? 322 SER A OG 1 ATOM 2074 N N . GLY A 1 271 ? -0.109 182.378 1.464 1.00 25.04 ? 323 GLY A N 1 ATOM 2075 C CA . GLY A 1 271 ? 0.397 182.637 2.800 1.00 29.11 ? 323 GLY A CA 1 ATOM 2076 C C . GLY A 1 271 ? 0.115 181.530 3.807 1.00 28.50 ? 323 GLY A C 1 ATOM 2077 O O . GLY A 1 271 ? 0.717 181.505 4.878 1.00 27.78 ? 323 GLY A O 1 ATOM 2078 N N . GLY A 1 272 ? -0.801 180.623 3.471 1.00 23.00 ? 324 GLY A N 1 ATOM 2079 C CA . GLY A 1 272 ? -1.176 179.538 4.370 1.00 20.49 ? 324 GLY A CA 1 ATOM 2080 C C . GLY A 1 272 ? -0.414 178.266 4.045 1.00 18.68 ? 324 GLY A C 1 ATOM 2081 O O . GLY A 1 272 ? 0.333 178.227 3.075 1.00 17.35 ? 324 GLY A O 1 ATOM 2082 N N . ASN A 1 273 ? -0.580 177.234 4.868 1.00 16.37 ? 325 ASN A N 1 ATOM 2083 C CA . ASN A 1 273 ? 0.022 175.936 4.576 1.00 15.38 ? 325 ASN A CA 1 ATOM 2084 C C . ASN A 1 273 ? -0.514 175.354 3.279 1.00 16.30 ? 325 ASN A C 1 ATOM 2085 O O . ASN A 1 273 ? -1.721 175.352 3.036 1.00 17.03 ? 325 ASN A O 1 ATOM 2086 C CB . ASN A 1 273 ? -0.217 174.952 5.724 1.00 17.35 ? 325 ASN A CB 1 ATOM 2087 C CG . ASN A 1 273 ? 0.792 175.105 6.843 1.00 20.86 ? 325 ASN A CG 1 ATOM 2088 O OD1 . ASN A 1 273 ? 1.866 174.494 6.830 1.00 27.42 ? 325 ASN A OD1 1 ATOM 2089 N ND2 . ASN A 1 273 ? 0.453 175.920 7.817 1.00 23.15 ? 325 ASN A ND2 1 ATOM 2090 N N . CYS A 1 274 ? 0.409 174.887 2.446 1.00 14.12 ? 326 CYS A N 1 ATOM 2091 C CA . CYS A 1 274 ? 0.093 174.234 1.188 1.00 14.71 ? 326 CYS A CA 1 ATOM 2092 C C . CYS A 1 274 ? 0.380 172.752 1.361 1.00 16.84 ? 326 CYS A C 1 ATOM 2093 O O . CYS A 1 274 ? 1.533 172.365 1.547 1.00 16.25 ? 326 CYS A O 1 ATOM 2094 C CB . CYS A 1 274 ? 0.921 174.824 0.046 1.00 15.20 ? 326 CYS A CB 1 ATOM 2095 S SG . CYS A 1 274 ? 0.190 174.658 -1.602 1.00 18.12 ? 326 CYS A SG 1 ATOM 2096 N N . PHE A 1 275 ? -0.671 171.938 1.314 1.00 11.41 ? 327 PHE A N 1 ATOM 2097 C CA . PHE A 1 275 ? -0.577 170.503 1.564 1.00 14.47 ? 327 PHE A CA 1 ATOM 2098 C C . PHE A 1 275 ? -0.525 169.739 0.248 1.00 14.97 ? 327 PHE A C 1 ATOM 2099 O O . PHE A 1 275 ? -1.484 169.747 -0.522 1.00 13.76 ? 327 PHE A O 1 ATOM 2100 C CB . PHE A 1 275 ? -1.766 170.019 2.406 1.00 13.48 ? 327 PHE A CB 1 ATOM 2101 C CG . PHE A 1 275 ? -1.822 170.624 3.784 1.00 12.34 ? 327 PHE A CG 1 ATOM 2102 C CD1 . PHE A 1 275 ? -1.038 170.116 4.807 1.00 14.50 ? 327 PHE A CD1 1 ATOM 2103 C CD2 . PHE A 1 275 ? -2.643 171.706 4.053 1.00 12.99 ? 327 PHE A CD2 1 ATOM 2104 C CE1 . PHE A 1 275 ? -1.081 170.664 6.076 1.00 13.28 ? 327 PHE A CE1 1 ATOM 2105 C CE2 . PHE A 1 275 ? -2.684 172.262 5.317 1.00 16.87 ? 327 PHE A CE2 1 ATOM 2106 C CZ . PHE A 1 275 ? -1.898 171.737 6.332 1.00 12.16 ? 327 PHE A CZ 1 ATOM 2107 N N . ARG A 1 276 ? 0.595 169.078 -0.017 1.00 12.91 ? 328 ARG A N 1 ATOM 2108 C CA . ARG A 1 276 ? 0.754 168.320 -1.246 1.00 12.88 ? 328 ARG A CA 1 ATOM 2109 C C . ARG A 1 276 ? 1.735 167.182 -1.039 1.00 12.55 ? 328 ARG A C 1 ATOM 2110 O O . ARG A 1 276 ? 2.692 167.306 -0.273 1.00 13.00 ? 328 ARG A O 1 ATOM 2111 C CB . ARG A 1 276 ? 1.234 169.218 -2.394 1.00 12.12 ? 328 ARG A CB 1 ATOM 2112 C CG . ARG A 1 276 ? 1.444 168.486 -3.716 1.00 12.15 ? 328 ARG A CG 1 ATOM 2113 C CD . ARG A 1 276 ? 1.636 169.435 -4.886 1.00 14.88 ? 328 ARG A CD 1 ATOM 2114 N NE . ARG A 1 276 ? 1.866 168.697 -6.126 1.00 14.03 ? 328 ARG A NE 1 ATOM 2115 C CZ . ARG A 1 276 ? 0.961 168.470 -7.078 1.00 15.11 ? 328 ARG A CZ 1 ATOM 2116 N NH1 . ARG A 1 276 ? -0.282 168.933 -6.976 1.00 14.23 ? 328 ARG A NH1 1 ATOM 2117 N NH2 . ARG A 1 276 ? 1.315 167.771 -8.148 1.00 15.83 ? 328 ARG A NH2 1 ATOM 2118 N N . SER A 1 277 ? 1.482 166.075 -1.728 1.00 13.91 ? 329 SER A N 1 ATOM 2119 C CA . SER A 1 277 ? 2.357 164.914 -1.709 1.00 12.73 ? 329 SER A CA 1 ATOM 2120 C C . SER A 1 277 ? 2.678 164.473 -0.286 1.00 13.21 ? 329 SER A C 1 ATOM 2121 O O . SER A 1 277 ? 3.827 164.209 0.062 1.00 11.26 ? 329 SER A O 1 ATOM 2122 C CB . SER A 1 277 ? 3.635 165.211 -2.496 1.00 13.94 ? 329 SER A CB 1 ATOM 2123 O OG . SER A 1 277 ? 3.292 165.553 -3.829 1.00 15.39 ? 329 SER A OG 1 ATOM 2124 N N . LEU A 1 278 ? 1.638 164.363 0.525 1.00 11.59 ? 330 LEU A N 1 ATOM 2125 C CA . LEU A 1 278 ? 1.814 164.089 1.942 1.00 10.35 ? 330 LEU A CA 1 ATOM 2126 C C . LEU A 1 278 ? 2.334 162.684 2.172 1.00 11.57 ? 330 LEU A C 1 ATOM 2127 O O . LEU A 1 278 ? 1.886 161.738 1.527 1.00 12.93 ? 330 LEU A O 1 ATOM 2128 C CB . LEU A 1 278 ? 0.496 164.273 2.692 1.00 11.76 ? 330 LEU A CB 1 ATOM 2129 C CG . LEU A 1 278 ? -0.083 165.688 2.694 1.00 12.35 ? 330 LEU A CG 1 ATOM 2130 C CD1 . LEU A 1 278 ? -1.389 165.711 3.473 1.00 12.86 ? 330 LEU A CD1 1 ATOM 2131 C CD2 . LEU A 1 278 ? 0.891 166.695 3.266 1.00 11.84 ? 330 LEU A CD2 1 ATOM 2132 N N . PRO A 1 279 ? 3.262 162.527 3.124 1.00 10.46 ? 331 PRO A N 1 ATOM 2133 C CA . PRO A 1 279 ? 3.652 161.180 3.523 1.00 11.20 ? 331 PRO A CA 1 ATOM 2134 C C . PRO A 1 279 ? 2.550 160.522 4.352 1.00 11.02 ? 331 PRO A C 1 ATOM 2135 O O . PRO A 1 279 ? 1.577 161.179 4.742 1.00 10.56 ? 331 PRO A O 1 ATOM 2136 C CB . PRO A 1 279 ? 4.923 161.421 4.341 1.00 11.29 ? 331 PRO A CB 1 ATOM 2137 C CG . PRO A 1 279 ? 4.715 162.735 4.969 1.00 10.80 ? 331 PRO A CG 1 ATOM 2138 C CD . PRO A 1 279 ? 3.893 163.550 3.978 1.00 10.60 ? 331 PRO A CD 1 ATOM 2139 N N . ALA A 1 280 ? 2.694 159.229 4.612 1.00 12.20 ? 332 ALA A N 1 ATOM 2140 C CA . ALA A 1 280 ? 1.673 158.483 5.323 1.00 11.12 ? 332 ALA A CA 1 ATOM 2141 C C . ALA A 1 280 ? 2.281 157.370 6.152 1.00 11.92 ? 332 ALA A C 1 ATOM 2142 O O . ALA A 1 280 ? 3.395 156.915 5.890 1.00 13.17 ? 332 ALA A O 1 ATOM 2143 C CB . ALA A 1 280 ? 0.650 157.908 4.336 1.00 11.79 ? 332 ALA A CB 1 ATOM 2144 N N . MET A 1 281 ? 1.530 156.951 7.166 1.00 12.45 ? 333 MET A N 1 ATOM 2145 C CA . MET A 1 281 ? 1.836 155.769 7.957 1.00 10.70 ? 333 MET A CA 1 ATOM 2146 C C . MET A 1 281 ? 0.877 154.638 7.603 1.00 12.90 ? 333 MET A C 1 ATOM 2147 O O . MET A 1 281 ? -0.334 154.830 7.635 1.00 13.83 ? 333 MET A O 1 ATOM 2148 C CB . MET A 1 281 ? 1.716 156.078 9.444 1.00 11.96 ? 333 MET A CB 1 ATOM 2149 C CG . MET A 1 281 ? 2.683 157.126 9.960 1.00 12.28 ? 333 MET A CG 1 ATOM 2150 S SD . MET A 1 281 ? 4.423 156.680 9.736 1.00 12.95 ? 333 MET A SD 1 ATOM 2151 C CE . MET A 1 281 ? 4.471 155.110 10.585 1.00 14.59 ? 333 MET A CE 1 ATOM 2152 N N . PHE A 1 282 ? 1.419 153.475 7.265 1.00 10.89 ? 334 PHE A N 1 ATOM 2153 C CA . PHE A 1 282 ? 0.617 152.275 7.062 1.00 13.10 ? 334 PHE A CA 1 ATOM 2154 C C . PHE A 1 282 ? 0.866 151.294 8.191 1.00 14.49 ? 334 PHE A C 1 ATOM 2155 O O . PHE A 1 282 ? 2.004 151.087 8.600 1.00 13.82 ? 334 PHE A O 1 ATOM 2156 C CB . PHE A 1 282 ? 0.944 151.637 5.718 1.00 13.60 ? 334 PHE A CB 1 ATOM 2157 C CG . PHE A 1 282 ? 0.059 150.475 5.368 1.00 15.78 ? 334 PHE A CG 1 ATOM 2158 C CD1 . PHE A 1 282 ? -1.267 150.683 5.029 1.00 16.84 ? 334 PHE A CD1 1 ATOM 2159 C CD2 . PHE A 1 282 ? 0.557 149.183 5.359 1.00 16.82 ? 334 PHE A CD2 1 ATOM 2160 C CE1 . PHE A 1 282 ? -2.091 149.620 4.700 1.00 17.81 ? 334 PHE A CE1 1 ATOM 2161 C CE2 . PHE A 1 282 ? -0.265 148.108 5.027 1.00 18.71 ? 334 PHE A CE2 1 ATOM 2162 C CZ . PHE A 1 282 ? -1.589 148.333 4.697 1.00 17.24 ? 334 PHE A CZ 1 ATOM 2163 N N . ASP A 1 283 ? -0.212 150.711 8.710 1.00 14.28 ? 335 ASP A N 1 ATOM 2164 C CA . ASP A 1 283 ? -0.130 149.701 9.753 1.00 13.77 ? 335 ASP A CA 1 ATOM 2165 C C . ASP A 1 283 ? -0.384 148.323 9.128 1.00 17.36 ? 335 ASP A C 1 ATOM 2166 O O . ASP A 1 283 ? -1.505 148.030 8.696 1.00 16.90 ? 335 ASP A O 1 ATOM 2167 C CB . ASP A 1 283 ? -1.139 150.024 10.856 1.00 18.24 ? 335 ASP A CB 1 ATOM 2168 C CG . ASP A 1 283 ? -0.987 149.143 12.085 1.00 18.24 ? 335 ASP A CG 1 ATOM 2169 O OD1 . ASP A 1 283 ? -0.597 147.965 11.953 1.00 21.01 ? 335 ASP A OD1 1 ATOM 2170 O OD2 . ASP A 1 283 ? -1.276 149.633 13.199 1.00 21.95 ? 335 ASP A OD2 1 ATOM 2171 N N . MET A 1 284 ? 0.661 147.497 9.063 1.00 15.68 ? 336 MET A N 1 ATOM 2172 C CA . MET A 1 284 ? 0.581 146.184 8.414 1.00 19.09 ? 336 MET A CA 1 ATOM 2173 C C . MET A 1 284 ? -0.407 145.264 9.108 1.00 21.16 ? 336 MET A C 1 ATOM 2174 O O . MET A 1 284 ? -0.945 144.350 8.483 1.00 23.07 ? 336 MET A O 1 ATOM 2175 C CB . MET A 1 284 ? 1.950 145.495 8.392 1.00 20.13 ? 336 MET A CB 1 ATOM 2176 C CG . MET A 1 284 ? 3.040 146.224 7.631 1.00 21.45 ? 336 MET A CG 1 ATOM 2177 S SD . MET A 1 284 ? 2.856 146.210 5.840 1.00 24.43 ? 336 MET A SD 1 ATOM 2178 C CE . MET A 1 284 ? 3.090 144.465 5.495 1.00 29.88 ? 336 MET A CE 1 ATOM 2179 N N . SER A 1 285 ? -0.633 145.481 10.398 1.00 18.38 ? 337 SER A N 1 ATOM 2180 C CA . SER A 1 285 ? -1.464 144.557 11.158 1.00 21.73 ? 337 SER A CA 1 ATOM 2181 C C . SER A 1 285 ? -2.951 144.902 11.026 1.00 24.79 ? 337 SER A C 1 ATOM 2182 O O . SER A 1 285 ? -3.786 143.999 11.002 1.00 26.84 ? 337 SER A O 1 ATOM 2183 C CB . SER A 1 285 ? -1.040 144.537 12.627 1.00 21.82 ? 337 SER A CB 1 ATOM 2184 O OG . SER A 1 285 ? -1.315 145.764 13.267 1.00 33.80 ? 337 SER A OG 1 ATOM 2185 N N . THR A 1 286 ? -3.279 146.187 10.908 1.00 21.32 ? 338 THR A N 1 ATOM 2186 C CA . THR A 1 286 ? -4.681 146.616 10.877 1.00 17.94 ? 338 THR A CA 1 ATOM 2187 C C . THR A 1 286 ? -5.148 147.089 9.502 1.00 20.00 ? 338 THR A C 1 ATOM 2188 O O . THR A 1 286 ? -6.354 147.210 9.259 1.00 22.74 ? 338 THR A O 1 ATOM 2189 C CB . THR A 1 286 ? -4.933 147.750 11.872 1.00 22.46 ? 338 THR A CB 1 ATOM 2190 O OG1 . THR A 1 286 ? -4.235 148.929 11.440 1.00 19.78 ? 338 THR A OG1 1 ATOM 2191 C CG2 . THR A 1 286 ? -4.466 147.358 13.268 1.00 24.24 ? 338 THR A CG2 1 ATOM 2192 N N . GLY A 1 287 ? -4.203 147.376 8.614 1.00 17.55 ? 339 GLY A N 1 ATOM 2193 C CA . GLY A 1 287 ? -4.514 147.934 7.313 1.00 18.23 ? 339 GLY A CA 1 ATOM 2194 C C . GLY A 1 287 ? -4.792 149.430 7.325 1.00 14.44 ? 339 GLY A C 1 ATOM 2195 O O . GLY A 1 287 ? -5.135 150.003 6.293 1.00 17.57 ? 339 GLY A O 1 ATOM 2196 N N . GLU A 1 288 ? -4.626 150.087 8.467 1.00 16.95 ? 340 GLU A N 1 ATOM 2197 C CA . GLU A 1 288 ? -4.899 151.515 8.518 1.00 16.04 ? 340 GLU A CA 1 ATOM 2198 C C . GLU A 1 288 ? -3.860 152.325 7.737 1.00 15.02 ? 340 GLU A C 1 ATOM 2199 O O . GLU A 1 288 ? -2.647 152.138 7.912 1.00 16.14 ? 340 GLU A O 1 ATOM 2200 C CB . GLU A 1 288 ? -4.961 152.013 9.960 1.00 17.28 ? 340 GLU A CB 1 ATOM 2201 C CG . GLU A 1 288 ? -5.275 153.500 10.034 1.00 16.33 ? 340 GLU A CG 1 ATOM 2202 C CD . GLU A 1 288 ? -5.637 153.968 11.423 1.00 21.44 ? 340 GLU A CD 1 ATOM 2203 O OE1 . GLU A 1 288 ? -5.329 153.250 12.399 1.00 28.60 ? 340 GLU A OE1 1 ATOM 2204 O OE2 . GLU A 1 288 ? -6.236 155.054 11.537 1.00 17.88 ? 340 GLU A OE2 1 ATOM 2205 N N . CYS A 1 289 ? -4.351 153.223 6.886 1.00 15.41 ? 341 CYS A N 1 ATOM 2206 C CA . CYS A 1 289 ? -3.526 154.191 6.165 1.00 14.72 ? 341 CYS A CA 1 ATOM 2207 C C . CYS A 1 289 ? -3.845 155.577 6.711 1.00 14.69 ? 341 CYS A C 1 ATOM 2208 O O . CYS A 1 289 ? -4.977 156.046 6.589 1.00 16.20 ? 341 CYS A O 1 ATOM 2209 C CB . CYS A 1 289 ? -3.790 154.121 4.655 1.00 15.55 ? 341 CYS A CB 1 ATOM 2210 S SG . CYS A 1 289 ? -2.907 155.331 3.647 1.00 19.91 ? 341 CYS A SG 1 ATOM 2211 N N . ARG A 1 290 ? -2.855 156.228 7.316 1.00 12.79 ? 342 ARG A N 1 ATOM 2212 C CA . ARG A 1 290 ? -3.049 157.544 7.927 1.00 12.33 ? 342 ARG A CA 1 ATOM 2213 C C . ARG A 1 290 ? -2.130 158.563 7.264 1.00 12.77 ? 342 ARG A C 1 ATOM 2214 O O . ARG A 1 290 ? -0.914 158.411 7.291 1.00 13.42 ? 342 ARG A O 1 ATOM 2215 C CB . ARG A 1 290 ? -2.776 157.486 9.428 1.00 11.86 ? 342 ARG A CB 1 ATOM 2216 C CG . ARG A 1 290 ? -3.313 158.677 10.188 1.00 13.23 ? 342 ARG A CG 1 ATOM 2217 C CD . ARG A 1 290 ? -4.777 158.448 10.577 1.00 13.41 ? 342 ARG A CD 1 ATOM 2218 N NE . ARG A 1 290 ? -5.353 159.624 11.221 1.00 12.50 ? 342 ARG A NE 1 ATOM 2219 C CZ . ARG A 1 290 ? -5.064 160.010 12.460 1.00 12.84 ? 342 ARG A CZ 1 ATOM 2220 N NH1 . ARG A 1 290 ? -4.194 159.315 13.182 1.00 12.14 ? 342 ARG A NH1 1 ATOM 2221 N NH2 . ARG A 1 290 ? -5.629 161.091 12.972 1.00 12.16 ? 342 ARG A NH2 1 ATOM 2222 N N . LEU A 1 291 ? -2.715 159.587 6.653 1.00 11.32 ? 343 LEU A N 1 ATOM 2223 C CA . LEU A 1 291 ? -1.946 160.669 6.052 1.00 10.93 ? 343 LEU A CA 1 ATOM 2224 C C . LEU A 1 291 ? -1.327 161.527 7.146 1.00 12.57 ? 343 LEU A C 1 ATOM 2225 O O . LEU A 1 291 ? -1.964 161.773 8.169 1.00 11.33 ? 343 LEU A O 1 ATOM 2226 C CB . LEU A 1 291 ? -2.834 161.530 5.155 1.00 11.89 ? 343 LEU A CB 1 ATOM 2227 C CG . LEU A 1 291 ? -3.521 160.801 3.997 1.00 12.00 ? 343 LEU A CG 1 ATOM 2228 C CD1 . LEU A 1 291 ? -4.424 161.771 3.262 1.00 14.66 ? 343 LEU A CD1 1 ATOM 2229 C CD2 . LEU A 1 291 ? -2.532 160.166 3.042 1.00 15.53 ? 343 LEU A CD2 1 ATOM 2230 N N . LEU A 1 292 ? -0.082 161.952 6.928 1.00 11.31 ? 344 LEU A N 1 ATOM 2231 C CA . LEU A 1 292 ? 0.599 162.884 7.823 1.00 12.84 ? 344 LEU A CA 1 ATOM 2232 C C . LEU A 1 292 ? 0.526 164.282 7.227 1.00 12.62 ? 344 LEU A C 1 ATOM 2233 O O . LEU A 1 292 ? 0.635 164.464 6.011 1.00 13.47 ? 344 LEU A O 1 ATOM 2234 C CB . LEU A 1 292 ? 2.051 162.481 8.045 1.00 12.05 ? 344 LEU A CB 1 ATOM 2235 C CG . LEU A 1 292 ? 2.291 161.071 8.586 1.00 10.67 ? 344 LEU A CG 1 ATOM 2236 C CD1 . LEU A 1 292 ? 3.790 160.795 8.678 1.00 12.96 ? 344 LEU A CD1 1 ATOM 2237 C CD2 . LEU A 1 292 ? 1.634 160.876 9.936 1.00 14.70 ? 344 LEU A CD2 1 ATOM 2238 N N . GLY A 1 293 ? 0.364 165.284 8.084 1.00 11.19 ? 345 GLY A N 1 ATOM 2239 C CA . GLY A 1 293 ? 0.209 166.649 7.619 1.00 11.64 ? 345 GLY A CA 1 ATOM 2240 C C . GLY A 1 293 ? 1.520 167.379 7.381 1.00 11.70 ? 345 GLY A C 1 ATOM 2241 O O . GLY A 1 293 ? 1.548 168.438 6.766 1.00 11.88 ? 345 GLY A O 1 ATOM 2242 N N . TYR A 1 294 ? 2.606 166.791 7.868 1.00 11.50 ? 346 TYR A N 1 ATOM 2243 C CA . TYR A 1 294 ? 3.927 167.413 7.825 1.00 11.64 ? 346 TYR A CA 1 ATOM 2244 C C . TYR A 1 294 ? 4.945 166.524 7.120 1.00 9.79 ? 346 TYR A C 1 ATOM 2245 O O . TYR A 1 294 ? 4.945 165.296 7.301 1.00 11.40 ? 346 TYR A O 1 ATOM 2246 C CB . TYR A 1 294 ? 4.423 167.701 9.240 1.00 11.11 ? 346 TYR A CB 1 ATOM 2247 C CG . TYR A 1 294 ? 3.658 168.734 10.040 1.00 10.30 ? 346 TYR A CG 1 ATOM 2248 C CD1 . TYR A 1 294 ? 3.175 169.895 9.451 1.00 11.74 ? 346 TYR A CD1 1 ATOM 2249 C CD2 . TYR A 1 294 ? 3.450 168.555 11.400 1.00 11.75 ? 346 TYR A CD2 1 ATOM 2250 C CE1 . TYR A 1 294 ? 2.499 170.854 10.203 1.00 14.18 ? 346 TYR A CE1 1 ATOM 2251 C CE2 . TYR A 1 294 ? 2.786 169.506 12.163 1.00 12.37 ? 346 TYR A CE2 1 ATOM 2252 C CZ . TYR A 1 294 ? 2.311 170.652 11.557 1.00 12.77 ? 346 TYR A CZ 1 ATOM 2253 O OH . TYR A 1 294 ? 1.638 171.608 12.313 1.00 13.60 ? 346 TYR A OH 1 ATOM 2254 N N . HIS A 1 295 ? 5.813 167.155 6.331 1.00 10.24 ? 347 HIS A N 1 ATOM 2255 C CA . HIS A 1 295 ? 6.908 166.479 5.640 1.00 10.92 ? 347 HIS A CA 1 ATOM 2256 C C . HIS A 1 295 ? 8.141 166.311 6.521 1.00 10.76 ? 347 HIS A C 1 ATOM 2257 O O . HIS A 1 295 ? 8.968 165.434 6.274 1.00 10.64 ? 347 HIS A O 1 ATOM 2258 C CB . HIS A 1 295 ? 7.304 167.242 4.385 1.00 9.88 ? 347 HIS A CB 1 ATOM 2259 C CG . HIS A 1 295 ? 6.218 167.325 3.364 1.00 10.41 ? 347 HIS A CG 1 ATOM 2260 N ND1 . HIS A 1 295 ? 5.913 166.284 2.515 1.00 11.98 ? 347 HIS A ND1 1 ATOM 2261 C CD2 . HIS A 1 295 ? 5.362 168.327 3.060 1.00 13.62 ? 347 HIS A CD2 1 ATOM 2262 C CE1 . HIS A 1 295 ? 4.914 166.646 1.726 1.00 12.59 ? 347 HIS A CE1 1 ATOM 2263 N NE2 . HIS A 1 295 ? 4.564 167.881 2.035 1.00 12.23 ? 347 HIS A NE2 1 ATOM 2264 N N . THR A 1 296 ? 8.254 167.157 7.539 1.00 9.71 ? 348 THR A N 1 ATOM 2265 C CA . THR A 1 296 ? 9.395 167.123 8.452 1.00 8.94 ? 348 THR A CA 1 ATOM 2266 C C . THR A 1 296 ? 9.543 165.734 9.059 1.00 11.51 ? 348 THR A C 1 ATOM 2267 O O . THR A 1 296 ? 8.566 165.141 9.512 1.00 11.39 ? 348 THR A O 1 ATOM 2268 C CB . THR A 1 296 ? 9.220 168.171 9.585 1.00 10.66 ? 348 THR A CB 1 ATOM 2269 O OG1 . THR A 1 296 ? 9.182 169.492 9.030 1.00 11.37 ? 348 THR A OG1 1 ATOM 2270 C CG2 . THR A 1 296 ? 10.369 168.102 10.568 1.00 11.69 ? 348 THR A CG2 1 ATOM 2271 N N . GLN A 1 297 ? 10.770 165.221 9.079 1.00 10.85 ? 349 GLN A N 1 ATOM 2272 C CA . GLN A 1 297 ? 11.048 163.943 9.731 1.00 10.23 ? 349 GLN A CA 1 ATOM 2273 C C . GLN A 1 297 ? 11.970 164.065 10.949 1.00 11.06 ? 349 GLN A C 1 ATOM 2274 O O . GLN A 1 297 ? 11.982 163.190 11.803 1.00 12.31 ? 349 GLN A O 1 ATOM 2275 C CB . GLN A 1 297 ? 11.643 162.980 8.707 1.00 10.23 ? 349 GLN A CB 1 ATOM 2276 C CG . GLN A 1 297 ? 10.613 162.493 7.690 1.00 11.04 ? 349 GLN A CG 1 ATOM 2277 C CD . GLN A 1 297 ? 11.227 162.255 6.330 1.00 9.36 ? 349 GLN A CD 1 ATOM 2278 O OE1 . GLN A 1 297 ? 11.967 161.293 6.135 1.00 11.86 ? 349 GLN A OE1 1 ATOM 2279 N NE2 . GLN A 1 297 ? 10.961 163.156 5.394 1.00 10.95 ? 349 GLN A NE2 1 ATOM 2280 N N . ASP A 1 298 ? 12.719 165.163 11.034 1.00 11.79 ? 350 ASP A N 1 ATOM 2281 C CA . ASP A 1 298 ? 13.640 165.401 12.151 1.00 10.29 ? 350 ASP A CA 1 ATOM 2282 C C . ASP A 1 298 ? 13.697 166.895 12.427 1.00 10.87 ? 350 ASP A C 1 ATOM 2283 O O . ASP A 1 298 ? 13.882 167.684 11.505 1.00 12.87 ? 350 ASP A O 1 ATOM 2284 C CB . ASP A 1 298 ? 15.039 164.859 11.822 1.00 10.73 ? 350 ASP A CB 1 ATOM 2285 C CG . ASP A 1 298 ? 15.953 164.779 13.038 1.00 15.65 ? 350 ASP A CG 1 ATOM 2286 O OD1 . ASP A 1 298 ? 16.448 165.828 13.493 1.00 16.31 ? 350 ASP A OD1 1 ATOM 2287 O OD2 . ASP A 1 298 ? 16.210 163.652 13.515 1.00 15.38 ? 350 ASP A OD2 1 ATOM 2288 N N . PHE A 1 299 ? 13.549 167.280 13.688 1.00 9.76 ? 351 PHE A N 1 ATOM 2289 C CA . PHE A 1 299 ? 13.687 168.678 14.092 1.00 9.97 ? 351 PHE A CA 1 ATOM 2290 C C . PHE A 1 299 ? 14.218 168.670 15.511 1.00 10.91 ? 351 PHE A C 1 ATOM 2291 O O . PHE A 1 299 ? 13.625 168.060 16.396 1.00 10.55 ? 351 PHE A O 1 ATOM 2292 C CB . PHE A 1 299 ? 12.356 169.429 13.999 1.00 10.53 ? 351 PHE A CB 1 ATOM 2293 C CG . PHE A 1 299 ? 12.472 170.921 14.231 1.00 11.06 ? 351 PHE A CG 1 ATOM 2294 C CD1 . PHE A 1 299 ? 13.390 171.672 13.518 1.00 10.07 ? 351 PHE A CD1 1 ATOM 2295 C CD2 . PHE A 1 299 ? 11.649 171.569 15.137 1.00 10.23 ? 351 PHE A CD2 1 ATOM 2296 C CE1 . PHE A 1 299 ? 13.496 173.037 13.715 1.00 12.46 ? 351 PHE A CE1 1 ATOM 2297 C CE2 . PHE A 1 299 ? 11.751 172.937 15.337 1.00 10.54 ? 351 PHE A CE2 1 ATOM 2298 C CZ . PHE A 1 299 ? 12.680 173.670 14.625 1.00 11.23 ? 351 PHE A CZ 1 ATOM 2299 N N . ARG A 1 300 ? 15.369 169.300 15.724 1.00 10.99 ? 352 ARG A N 1 ATOM 2300 C CA . ARG A 1 300 ? 16.028 169.239 17.024 1.00 10.36 ? 352 ARG A CA 1 ATOM 2301 C C . ARG A 1 300 ? 16.796 170.528 17.314 1.00 11.89 ? 352 ARG A C 1 ATOM 2302 O O . ARG A 1 300 ? 17.708 170.539 18.141 1.00 14.37 ? 352 ARG A O 1 ATOM 2303 C CB . ARG A 1 300 ? 16.968 168.033 17.093 1.00 13.26 ? 352 ARG A CB 1 ATOM 2304 C CG . ARG A 1 300 ? 18.100 168.066 16.083 1.00 10.88 ? 352 ARG A CG 1 ATOM 2305 C CD . ARG A 1 300 ? 19.014 166.856 16.224 1.00 12.01 ? 352 ARG A CD 1 ATOM 2306 N NE . ARG A 1 300 ? 18.419 165.628 15.707 1.00 12.83 ? 352 ARG A NE 1 ATOM 2307 C CZ . ARG A 1 300 ? 18.948 164.420 15.866 1.00 12.76 ? 352 ARG A CZ 1 ATOM 2308 N NH1 . ARG A 1 300 ? 20.083 164.275 16.541 1.00 13.20 ? 352 ARG A NH1 1 ATOM 2309 N NH2 . ARG A 1 300 ? 18.337 163.359 15.351 1.00 14.13 ? 352 ARG A NH2 1 ATOM 2310 N N . SER A 1 301 ? 16.408 171.605 16.640 1.00 10.95 ? 353 SER A N 1 ATOM 2311 C CA . SER A 1 301 ? 16.970 172.933 16.882 1.00 14.40 ? 353 SER A CA 1 ATOM 2312 C C . SER A 1 301 ? 16.695 173.453 18.280 1.00 13.27 ? 353 SER A C 1 ATOM 2313 O O . SER A 1 301 ? 15.801 172.972 18.967 1.00 13.91 ? 353 SER A O 1 ATOM 2314 C CB . SER A 1 301 ? 16.394 173.921 15.874 1.00 17.25 ? 353 SER A CB 1 ATOM 2315 O OG . SER A 1 301 ? 16.709 173.527 14.556 1.00 23.58 ? 353 SER A OG 1 ATOM 2316 N N . SER A 1 302 ? 17.445 174.477 18.679 1.00 12.84 ? 354 SER A N 1 ATOM 2317 C CA . SER A 1 302 ? 17.263 175.087 19.984 1.00 13.34 ? 354 SER A CA 1 ATOM 2318 C C . SER A 1 302 ? 15.863 175.663 20.168 1.00 14.96 ? 354 SER A C 1 ATOM 2319 O O . SER A 1 302 ? 15.420 175.858 21.296 1.00 18.40 ? 354 SER A O 1 ATOM 2320 C CB . SER A 1 302 ? 18.292 176.191 20.197 1.00 16.13 ? 354 SER A CB 1 ATOM 2321 O OG . SER A 1 302 ? 18.153 177.190 19.219 1.00 19.20 ? 354 SER A OG 1 ATOM 2322 N N . THR A 1 303 ? 15.174 175.920 19.059 1.00 14.05 ? 355 THR A N 1 ATOM 2323 C CA . THR A 1 303 ? 13.827 176.473 19.096 1.00 15.62 ? 355 THR A CA 1 ATOM 2324 C C . THR A 1 303 ? 12.725 175.418 19.100 1.00 15.92 ? 355 THR A C 1 ATOM 2325 O O . THR A 1 303 ? 11.549 175.770 19.186 1.00 15.75 ? 355 THR A O 1 ATOM 2326 C CB . THR A 1 303 ? 13.577 177.384 17.889 1.00 15.91 ? 355 THR A CB 1 ATOM 2327 O OG1 . THR A 1 303 ? 13.830 176.652 16.686 1.00 20.10 ? 355 THR A OG1 1 ATOM 2328 C CG2 . THR A 1 303 ? 14.477 178.610 17.939 1.00 21.96 ? 355 THR A CG2 1 ATOM 2329 N N . CYS A 1 304 ? 13.080 174.141 19.003 1.00 12.56 ? 356 CYS A N 1 ATOM 2330 C CA . CYS A 1 304 ? 12.051 173.105 18.929 1.00 13.40 ? 356 CYS A CA 1 ATOM 2331 C C . CYS A 1 304 ? 11.374 172.969 20.292 1.00 14.33 ? 356 CYS A C 1 ATOM 2332 O O . CYS A 1 304 ? 12.008 173.135 21.335 1.00 16.18 ? 356 CYS A O 1 ATOM 2333 C CB . CYS A 1 304 ? 12.623 171.761 18.452 1.00 12.82 ? 356 CYS A CB 1 ATOM 2334 S SG . CYS A 1 304 ? 13.677 170.812 19.598 1.00 19.16 ? 356 CYS A SG 1 ATOM 2335 N N . ALA A 1 305 ? 10.074 172.691 20.268 1.00 13.25 ? 357 ALA A N 1 ATOM 2336 C CA . ALA A 1 305 ? 9.305 172.493 21.490 1.00 14.10 ? 357 ALA A CA 1 ATOM 2337 C C . ALA A 1 305 ? 9.455 171.064 21.993 1.00 12.99 ? 357 ALA A C 1 ATOM 2338 O O . ALA A 1 305 ? 9.212 170.113 21.255 1.00 13.49 ? 357 ALA A O 1 ATOM 2339 C CB . ALA A 1 305 ? 7.833 172.820 21.249 1.00 14.79 ? 357 ALA A CB 1 ATOM 2340 N N . GLU A 1 306 ? 9.856 170.914 23.251 1.00 13.92 ? 358 GLU A N 1 ATOM 2341 C CA . GLU A 1 306 ? 10.059 169.595 23.834 1.00 12.47 ? 358 GLU A CA 1 ATOM 2342 C C . GLU A 1 306 ? 8.773 169.043 24.450 1.00 14.25 ? 358 GLU A C 1 ATOM 2343 O O . GLU A 1 306 ? 8.421 169.383 25.585 1.00 14.26 ? 358 GLU A O 1 ATOM 2344 C CB . GLU A 1 306 ? 11.159 169.636 24.894 1.00 13.68 ? 358 GLU A CB 1 ATOM 2345 C CG . GLU A 1 306 ? 12.537 170.000 24.348 1.00 14.27 ? 358 GLU A CG 1 ATOM 2346 C CD . GLU A 1 306 ? 13.625 169.899 25.410 1.00 17.29 ? 358 GLU A CD 1 ATOM 2347 O OE1 . GLU A 1 306 ? 14.547 169.073 25.248 1.00 14.88 ? 358 GLU A OE1 1 ATOM 2348 O OE2 . GLU A 1 306 ? 13.555 170.648 26.411 1.00 21.59 ? 358 GLU A OE2 1 ATOM 2349 N N . LEU A 1 307 ? 8.098 168.197 23.665 1.00 13.18 ? 359 LEU A N 1 ATOM 2350 C CA . LEU A 1 307 ? 6.918 167.400 24.050 1.00 13.18 ? 359 LEU A CA 1 ATOM 2351 C C . LEU A 1 307 ? 5.623 168.194 24.254 1.00 13.06 ? 359 LEU A C 1 ATOM 2352 O O . LEU A 1 307 ? 4.566 167.749 23.806 1.00 14.40 ? 359 LEU A O 1 ATOM 2353 C CB . LEU A 1 307 ? 7.215 166.576 25.307 1.00 12.10 ? 359 LEU A CB 1 ATOM 2354 C CG . LEU A 1 307 ? 8.298 165.495 25.152 1.00 14.73 ? 359 LEU A CG 1 ATOM 2355 C CD1 . LEU A 1 307 ? 8.547 164.779 26.475 1.00 15.47 ? 359 LEU A CD1 1 ATOM 2356 C CD2 . LEU A 1 307 ? 7.941 164.480 24.066 1.00 16.11 ? 359 LEU A CD2 1 ATOM 2357 N N . THR A 1 308 ? 5.686 169.343 24.921 1.00 10.70 ? 360 THR A N 1 ATOM 2358 C CA . THR A 1 308 ? 4.506 170.183 25.103 1.00 12.60 ? 360 THR A CA 1 ATOM 2359 C C . THR A 1 308 ? 4.858 171.651 24.972 1.00 13.55 ? 360 THR A C 1 ATOM 2360 O O . THR A 1 308 ? 5.907 172.101 25.447 1.00 13.67 ? 360 THR A O 1 ATOM 2361 C CB . THR A 1 308 ? 3.832 169.938 26.479 1.00 14.68 ? 360 THR A CB 1 ATOM 2362 O OG1 . THR A 1 308 ? 4.778 170.137 27.536 1.00 16.96 ? 360 THR A OG1 1 ATOM 2363 C CG2 . THR A 1 308 ? 3.295 168.522 26.572 1.00 14.61 ? 360 THR A CG2 1 ATOM 2364 N N . THR A 1 309 ? 3.985 172.389 24.292 1.00 12.74 ? 361 THR A N 1 ATOM 2365 C CA . THR A 1 309 ? 4.060 173.845 24.227 1.00 12.64 ? 361 THR A CA 1 ATOM 2366 C C . THR A 1 309 ? 2.683 174.397 23.903 1.00 13.94 ? 361 THR A C 1 ATOM 2367 O O . THR A 1 309 ? 1.836 173.674 23.385 1.00 13.89 ? 361 THR A O 1 ATOM 2368 C CB . THR A 1 309 ? 5.056 174.346 23.159 1.00 13.51 ? 361 THR A CB 1 ATOM 2369 O OG1 . THR A 1 309 ? 5.162 175.772 23.242 1.00 16.37 ? 361 THR A OG1 1 ATOM 2370 C CG2 . THR A 1 309 ? 4.601 173.970 21.759 1.00 13.13 ? 361 THR A CG2 1 ATOM 2371 N N . ASP A 1 310 ? 2.473 175.680 24.188 1.00 15.15 ? 362 ASP A N 1 ATOM 2372 C CA . ASP A 1 310 ? 1.259 176.376 23.756 1.00 16.94 ? 362 ASP A CA 1 ATOM 2373 C C . ASP A 1 310 ? 1.499 177.277 22.542 1.00 16.40 ? 362 ASP A C 1 ATOM 2374 O O . ASP A 1 310 ? 0.556 177.835 21.974 1.00 16.20 ? 362 ASP A O 1 ATOM 2375 C CB . ASP A 1 310 ? 0.702 177.222 24.898 1.00 13.99 ? 362 ASP A CB 1 ATOM 2376 C CG . ASP A 1 310 ? 0.301 176.392 26.090 1.00 23.99 ? 362 ASP A CG 1 ATOM 2377 O OD1 . ASP A 1 310 ? -0.360 175.352 25.892 1.00 20.44 ? 362 ASP A OD1 1 ATOM 2378 O OD2 . ASP A 1 310 ? 0.652 176.780 27.224 1.00 33.61 ? 362 ASP A OD2 1 ATOM 2379 N N . ASP A 1 311 ? 2.761 177.429 22.156 1.00 13.72 ? 363 ASP A N 1 ATOM 2380 C CA . ASP A 1 311 ? 3.149 178.359 21.093 1.00 13.53 ? 363 ASP A CA 1 ATOM 2381 C C . ASP A 1 311 ? 2.822 177.782 19.725 1.00 14.02 ? 363 ASP A C 1 ATOM 2382 O O . ASP A 1 311 ? 3.512 176.879 19.257 1.00 15.14 ? 363 ASP A O 1 ATOM 2383 C CB . ASP A 1 311 ? 4.646 178.666 21.210 1.00 15.03 ? 363 ASP A CB 1 ATOM 2384 C CG . ASP A 1 311 ? 5.131 179.701 20.204 1.00 17.84 ? 363 ASP A CG 1 ATOM 2385 O OD1 . ASP A 1 311 ? 4.354 180.137 19.332 1.00 15.58 ? 363 ASP A OD1 1 ATOM 2386 O OD2 . ASP A 1 311 ? 6.322 180.074 20.296 1.00 21.03 ? 363 ASP A OD2 1 ATOM 2387 N N . THR A 1 312 ? 1.776 178.301 19.086 1.00 15.24 ? 364 THR A N 1 ATOM 2388 C CA . THR A 1 312 ? 1.324 177.741 17.817 1.00 16.00 ? 364 THR A CA 1 ATOM 2389 C C . THR A 1 312 ? 2.246 178.115 16.658 1.00 18.24 ? 364 THR A C 1 ATOM 2390 O O . THR A 1 312 ? 2.045 177.645 15.533 1.00 21.75 ? 364 THR A O 1 ATOM 2391 C CB . THR A 1 312 ? -0.119 178.173 17.482 1.00 16.95 ? 364 THR A CB 1 ATOM 2392 O OG1 . THR A 1 312 ? -0.193 179.602 17.363 1.00 21.71 ? 364 THR A OG1 1 ATOM 2393 C CG2 . THR A 1 312 ? -1.072 177.708 18.570 1.00 19.41 ? 364 THR A CG2 1 ATOM 2394 N N . ASN A 1 313 ? 3.266 178.926 16.924 1.00 15.62 ? 365 ASN A N 1 ATOM 2395 C CA . ASN A 1 313 ? 4.269 179.209 15.902 1.00 18.46 ? 365 ASN A CA 1 ATOM 2396 C C . ASN A 1 313 ? 5.510 178.329 16.064 1.00 19.21 ? 365 ASN A C 1 ATOM 2397 O O . ASN A 1 313 ? 6.435 178.401 15.251 1.00 21.15 ? 365 ASN A O 1 ATOM 2398 C CB . ASN A 1 313 ? 4.662 180.688 15.924 1.00 22.96 ? 365 ASN A CB 1 ATOM 2399 C CG . ASN A 1 313 ? 5.237 181.151 14.596 1.00 39.79 ? 365 ASN A CG 1 ATOM 2400 O OD1 . ASN A 1 313 ? 6.350 181.674 14.535 1.00 50.03 ? 365 ASN A OD1 1 ATOM 2401 N ND2 . ASN A 1 313 ? 4.483 180.937 13.518 1.00 48.00 ? 365 ASN A ND2 1 ATOM 2402 N N . ALA A 1 314 ? 5.526 177.486 17.096 1.00 15.18 ? 366 ALA A N 1 ATOM 2403 C CA . ALA A 1 314 ? 6.647 176.580 17.315 1.00 13.53 ? 366 ALA A CA 1 ATOM 2404 C C . ALA A 1 314 ? 6.385 175.236 16.647 1.00 15.08 ? 366 ALA A C 1 ATOM 2405 O O . ALA A 1 314 ? 5.244 174.904 16.306 1.00 16.50 ? 366 ALA A O 1 ATOM 2406 C CB . ALA A 1 314 ? 6.907 176.393 18.809 1.00 16.09 ? 366 ALA A CB 1 ATOM 2407 N N . PHE A 1 315 ? 7.465 174.498 16.419 1.00 11.76 ? 367 PHE A N 1 ATOM 2408 C CA . PHE A 1 315 ? 7.398 173.148 15.885 1.00 11.33 ? 367 PHE A CA 1 ATOM 2409 C C . PHE A 1 315 ? 8.047 172.210 16.891 1.00 12.37 ? 367 PHE A C 1 ATOM 2410 O O . PHE A 1 315 ? 9.048 172.551 17.521 1.00 11.55 ? 367 PHE A O 1 ATOM 2411 C CB . PHE A 1 315 ? 8.086 173.053 14.512 1.00 12.17 ? 367 PHE A CB 1 ATOM 2412 C CG . PHE A 1 315 ? 7.628 171.875 13.684 1.00 13.36 ? 367 PHE A CG 1 ATOM 2413 C CD1 . PHE A 1 315 ? 8.185 170.617 13.870 1.00 12.26 ? 367 PHE A CD1 1 ATOM 2414 C CD2 . PHE A 1 315 ? 6.630 172.022 12.724 1.00 12.66 ? 367 PHE A CD2 1 ATOM 2415 C CE1 . PHE A 1 315 ? 7.752 169.525 13.123 1.00 11.33 ? 367 PHE A CE1 1 ATOM 2416 C CE2 . PHE A 1 315 ? 6.200 170.925 11.971 1.00 11.64 ? 367 PHE A CE2 1 ATOM 2417 C CZ . PHE A 1 315 ? 6.768 169.688 12.168 1.00 12.21 ? 367 PHE A CZ 1 ATOM 2418 N N . TYR A 1 316 ? 7.460 171.034 17.060 1.00 10.78 ? 368 TYR A N 1 ATOM 2419 C CA . TYR A 1 316 ? 7.927 170.076 18.042 1.00 9.35 ? 368 TYR A CA 1 ATOM 2420 C C . TYR A 1 316 ? 9.233 169.381 17.675 1.00 11.06 ? 368 TYR A C 1 ATOM 2421 O O . TYR A 1 316 ? 9.530 169.138 16.500 1.00 10.19 ? 368 TYR A O 1 ATOM 2422 C CB . TYR A 1 316 ? 6.848 169.017 18.279 1.00 10.07 ? 368 TYR A CB 1 ATOM 2423 C CG . TYR A 1 316 ? 5.792 169.474 19.251 1.00 10.55 ? 368 TYR A CG 1 ATOM 2424 C CD1 . TYR A 1 316 ? 6.070 169.520 20.609 1.00 12.87 ? 368 TYR A CD1 1 ATOM 2425 C CD2 . TYR A 1 316 ? 4.533 169.883 18.822 1.00 10.66 ? 368 TYR A CD2 1 ATOM 2426 C CE1 . TYR A 1 316 ? 5.131 169.956 21.514 1.00 13.21 ? 368 TYR A CE1 1 ATOM 2427 C CE2 . TYR A 1 316 ? 3.578 170.310 19.731 1.00 11.00 ? 368 TYR A CE2 1 ATOM 2428 C CZ . TYR A 1 316 ? 3.885 170.340 21.072 1.00 12.00 ? 368 TYR A CZ 1 ATOM 2429 O OH . TYR A 1 316 ? 2.962 170.762 22.010 1.00 12.60 ? 368 TYR A OH 1 ATOM 2430 N N . CYS A 1 317 ? 10.012 169.079 18.710 1.00 10.49 ? 369 CYS A N 1 ATOM 2431 C CA . CYS A 1 317 ? 11.187 168.226 18.582 1.00 11.69 ? 369 CYS A CA 1 ATOM 2432 C C . CYS A 1 317 ? 10.724 166.847 18.148 1.00 10.50 ? 369 CYS A C 1 ATOM 2433 O O . CYS A 1 317 ? 9.952 166.214 18.862 1.00 11.60 ? 369 CYS A O 1 ATOM 2434 C CB . CYS A 1 317 ? 11.934 168.117 19.906 1.00 11.77 ? 369 CYS A CB 1 ATOM 2435 S SG . CYS A 1 317 ? 12.406 169.682 20.702 1.00 18.34 ? 369 CYS A SG 1 ATOM 2436 N N . VAL A 1 318 ? 11.180 166.383 16.992 1.00 9.35 ? 370 VAL A N 1 ATOM 2437 C CA . VAL A 1 318 ? 10.813 165.053 16.522 1.00 8.89 ? 370 VAL A CA 1 ATOM 2438 C C . VAL A 1 318 ? 12.011 164.401 15.860 1.00 10.76 ? 370 VAL A C 1 ATOM 2439 O O . VAL A 1 318 ? 12.925 165.085 15.409 1.00 11.33 ? 370 VAL A O 1 ATOM 2440 C CB . VAL A 1 318 ? 9.626 165.076 15.504 1.00 10.41 ? 370 VAL A CB 1 ATOM 2441 C CG1 . VAL A 1 318 ? 8.380 165.673 16.124 1.00 11.57 ? 370 VAL A CG1 1 ATOM 2442 C CG2 . VAL A 1 318 ? 9.995 165.827 14.228 1.00 13.02 ? 370 VAL A CG2 1 ATOM 2443 N N . ARG A 1 319 ? 12.006 163.078 15.790 1.00 9.39 ? 371 ARG A N 1 ATOM 2444 C CA . ARG A 1 319 ? 13.001 162.383 14.978 1.00 9.78 ? 371 ARG A CA 1 ATOM 2445 C C . ARG A 1 319 ? 12.478 161.009 14.621 1.00 10.11 ? 371 ARG A C 1 ATOM 2446 O O . ARG A 1 319 ? 11.614 160.483 15.320 1.00 11.37 ? 371 ARG A O 1 ATOM 2447 C CB . ARG A 1 319 ? 14.347 162.277 15.705 1.00 11.61 ? 371 ARG A CB 1 ATOM 2448 C CG . ARG A 1 319 ? 14.358 161.357 16.924 1.00 11.49 ? 371 ARG A CG 1 ATOM 2449 C CD . ARG A 1 319 ? 15.679 161.476 17.700 1.00 13.10 ? 371 ARG A CD 1 ATOM 2450 N NE . ARG A 1 319 ? 15.883 162.849 18.134 1.00 12.39 ? 371 ARG A NE 1 ATOM 2451 C CZ . ARG A 1 319 ? 16.995 163.331 18.679 1.00 11.06 ? 371 ARG A CZ 1 ATOM 2452 N NH1 . ARG A 1 319 ? 18.060 162.560 18.872 1.00 13.39 ? 371 ARG A NH1 1 ATOM 2453 N NH2 . ARG A 1 319 ? 17.030 164.612 19.015 1.00 12.92 ? 371 ARG A NH2 1 ATOM 2454 N N . PRO A 1 320 ? 12.991 160.420 13.531 1.00 10.48 ? 372 PRO A N 1 ATOM 2455 C CA . PRO A 1 320 ? 12.547 159.067 13.206 1.00 10.69 ? 372 PRO A CA 1 ATOM 2456 C C . PRO A 1 320 ? 13.112 158.051 14.177 1.00 11.74 ? 372 PRO A C 1 ATOM 2457 O O . PRO A 1 320 ? 14.254 158.186 14.625 1.00 13.00 ? 372 PRO A O 1 ATOM 2458 C CB . PRO A 1 320 ? 13.098 158.835 11.794 1.00 11.55 ? 372 PRO A CB 1 ATOM 2459 C CG . PRO A 1 320 ? 13.591 160.170 11.321 1.00 13.89 ? 372 PRO A CG 1 ATOM 2460 C CD . PRO A 1 320 ? 13.962 160.920 12.547 1.00 12.09 ? 372 PRO A CD 1 ATOM 2461 N N . MET A 1 321 ? 12.312 157.041 14.497 1.00 10.91 ? 373 MET A N 1 ATOM 2462 C CA . MET A 1 321 ? 12.742 155.962 15.371 1.00 10.73 ? 373 MET A CA 1 ATOM 2463 C C . MET A 1 321 ? 12.206 154.638 14.875 1.00 11.40 ? 373 MET A C 1 ATOM 2464 O O . MET A 1 321 ? 11.109 154.572 14.319 1.00 12.33 ? 373 MET A O 1 ATOM 2465 C CB . MET A 1 321 ? 12.269 156.169 16.815 1.00 12.21 ? 373 MET A CB 1 ATOM 2466 C CG . MET A 1 321 ? 12.954 157.280 17.576 1.00 14.17 ? 373 MET A CG 1 ATOM 2467 S SD . MET A 1 321 ? 12.347 157.377 19.277 1.00 17.03 ? 373 MET A SD 1 ATOM 2468 C CE . MET A 1 321 ? 12.922 155.833 19.958 1.00 19.33 ? 373 MET A CE 1 ATOM 2469 N N . LYS A 1 322 ? 12.989 153.588 15.082 1.00 11.04 ? 374 LYS A N 1 ATOM 2470 C CA . LYS A 1 322 ? 12.522 152.215 14.925 1.00 10.37 ? 374 LYS A CA 1 ATOM 2471 C C . LYS A 1 322 ? 12.743 151.461 16.216 1.00 13.14 ? 374 LYS A C 1 ATOM 2472 O O . LYS A 1 322 ? 13.781 151.614 16.851 1.00 12.95 ? 374 LYS A O 1 ATOM 2473 C CB . LYS A 1 322 ? 13.261 151.495 13.804 1.00 10.55 ? 374 LYS A CB 1 ATOM 2474 C CG . LYS A 1 322 ? 13.109 152.131 12.448 1.00 13.03 ? 374 LYS A CG 1 ATOM 2475 C CD . LYS A 1 322 ? 13.695 151.280 11.331 1.00 11.14 ? 374 LYS A CD 1 ATOM 2476 C CE . LYS A 1 322 ? 13.511 151.947 10.005 1.00 10.26 ? 374 LYS A CE 1 ATOM 2477 N NZ . LYS A 1 322 ? 14.028 151.113 8.886 1.00 13.89 ? 374 LYS A NZ 1 ATOM 2478 N N . THR A 1 323 ? 11.779 150.621 16.584 1.00 12.66 ? 375 THR A N 1 ATOM 2479 C CA . THR A 1 323 ? 11.922 149.724 17.725 1.00 12.86 ? 375 THR A CA 1 ATOM 2480 C C . THR A 1 323 ? 11.346 148.384 17.316 1.00 11.87 ? 375 THR A C 1 ATOM 2481 O O . THR A 1 323 ? 10.644 148.299 16.313 1.00 12.34 ? 375 THR A O 1 ATOM 2482 C CB . THR A 1 323 ? 11.185 150.233 18.970 1.00 12.21 ? 375 THR A CB 1 ATOM 2483 O OG1 . THR A 1 323 ? 9.782 150.304 18.689 1.00 14.62 ? 375 THR A OG1 1 ATOM 2484 C CG2 . THR A 1 323 ? 11.699 151.592 19.371 1.00 14.92 ? 375 THR A CG2 1 ATOM 2485 N N . ALA A 1 324 ? 11.622 147.334 18.085 1.00 13.48 ? 376 ALA A N 1 ATOM 2486 C CA . ALA A 1 324 ? 11.021 146.050 17.774 1.00 12.57 ? 376 ALA A CA 1 ATOM 2487 C C . ALA A 1 324 ? 9.502 146.206 17.682 1.00 12.17 ? 376 ALA A C 1 ATOM 2488 O O . ALA A 1 324 ? 8.862 145.688 16.761 1.00 15.69 ? 376 ALA A O 1 ATOM 2489 C CB . ALA A 1 324 ? 11.391 145.014 18.813 1.00 16.75 ? 376 ALA A CB 1 ATOM 2490 N N . ALA A 1 325 ? 8.933 146.952 18.623 1.00 13.32 ? 377 ALA A N 1 ATOM 2491 C CA . ALA A 1 325 ? 7.485 147.115 18.705 1.00 14.57 ? 377 ALA A CA 1 ATOM 2492 C C . ALA A 1 325 ? 6.895 147.935 17.550 1.00 15.98 ? 377 ALA A C 1 ATOM 2493 O O . ALA A 1 325 ? 5.705 147.829 17.272 1.00 18.36 ? 377 ALA A O 1 ATOM 2494 C CB . ALA A 1 325 ? 7.110 147.750 20.029 1.00 17.07 ? 377 ALA A CB 1 ATOM 2495 N N . SER A 1 326 ? 7.706 148.746 16.875 1.00 12.92 ? 378 SER A N 1 ATOM 2496 C CA . SER A 1 326 ? 7.194 149.543 15.757 1.00 11.66 ? 378 SER A CA 1 ATOM 2497 C C . SER A 1 326 ? 7.209 148.777 14.426 1.00 13.41 ? 378 SER A C 1 ATOM 2498 O O . SER A 1 326 ? 6.935 149.359 13.387 1.00 12.73 ? 378 SER A O 1 ATOM 2499 C CB . SER A 1 326 ? 7.993 150.852 15.619 1.00 10.92 ? 378 SER A CB 1 ATOM 2500 O OG . SER A 1 326 ? 9.271 150.657 15.051 1.00 12.50 ? 378 SER A OG 1 ATOM 2501 N N . SER A 1 327 ? 7.500 147.477 14.456 1.00 13.51 ? 379 SER A N 1 ATOM 2502 C CA . SER A 1 327 ? 7.731 146.730 13.224 1.00 12.96 ? 379 SER A CA 1 ATOM 2503 C C . SER A 1 327 ? 6.492 146.491 12.372 1.00 14.15 ? 379 SER A C 1 ATOM 2504 O O . SER A 1 327 ? 6.610 145.996 11.254 1.00 16.32 ? 379 SER A O 1 ATOM 2505 C CB . SER A 1 327 ? 8.376 145.387 13.534 1.00 13.49 ? 379 SER A CB 1 ATOM 2506 O OG . SER A 1 327 ? 9.650 145.568 14.125 1.00 14.99 ? 379 SER A OG 1 ATOM 2507 N N . ASN A 1 328 ? 5.320 146.835 12.890 1.00 13.72 ? 380 ASN A N 1 ATOM 2508 C CA . ASN A 1 328 ? 4.093 146.783 12.106 1.00 17.20 ? 380 ASN A CA 1 ATOM 2509 C C . ASN A 1 328 ? 3.843 148.065 11.312 1.00 14.04 ? 380 ASN A C 1 ATOM 2510 O O . ASN A 1 328 ? 2.993 148.098 10.424 1.00 15.40 ? 380 ASN A O 1 ATOM 2511 C CB . ASN A 1 328 ? 2.901 146.516 13.022 1.00 17.55 ? 380 ASN A CB 1 ATOM 2512 C CG . ASN A 1 328 ? 2.752 147.574 14.121 1.00 24.26 ? 380 ASN A CG 1 ATOM 2513 O OD1 . ASN A 1 328 ? 3.728 147.957 14.785 1.00 22.37 ? 380 ASN A OD1 1 ATOM 2514 N ND2 . ASN A 1 328 ? 1.526 148.055 14.312 1.00 26.63 ? 380 ASN A ND2 1 ATOM 2515 N N . MET A 1 329 ? 4.588 149.123 11.632 1.00 11.09 ? 381 MET A N 1 ATOM 2516 C CA . MET A 1 329 ? 4.384 150.429 11.019 1.00 13.10 ? 381 MET A CA 1 ATOM 2517 C C . MET A 1 329 ? 5.299 150.629 9.826 1.00 12.96 ? 381 MET A C 1 ATOM 2518 O O . MET A 1 329 ? 6.399 150.081 9.773 1.00 14.41 ? 381 MET A O 1 ATOM 2519 C CB . MET A 1 329 ? 4.623 151.542 12.040 1.00 13.47 ? 381 MET A CB 1 ATOM 2520 C CG . MET A 1 329 ? 3.717 151.501 13.256 1.00 13.53 ? 381 MET A CG 1 ATOM 2521 S SD . MET A 1 329 ? 1.955 151.351 12.857 1.00 19.07 ? 381 MET A SD 1 ATOM 2522 C CE . MET A 1 329 ? 1.718 152.773 11.809 1.00 15.32 ? 381 MET A CE 1 ATOM 2523 N N . VAL A 1 330 ? 4.815 151.409 8.866 1.00 11.45 ? 382 VAL A N 1 ATOM 2524 C CA . VAL A 1 330 ? 5.552 151.697 7.646 1.00 12.57 ? 382 VAL A CA 1 ATOM 2525 C C . VAL A 1 330 ? 5.421 153.175 7.321 1.00 12.10 ? 382 VAL A C 1 ATOM 2526 O O . VAL A 1 330 ? 4.312 153.691 7.227 1.00 11.60 ? 382 VAL A O 1 ATOM 2527 C CB . VAL A 1 330 ? 5.031 150.877 6.442 1.00 12.67 ? 382 VAL A CB 1 ATOM 2528 C CG1 . VAL A 1 330 ? 6.031 150.877 5.322 1.00 12.67 ? 382 VAL A CG1 1 ATOM 2529 C CG2 . VAL A 1 330 ? 4.688 149.443 6.843 1.00 15.15 ? 382 VAL A CG2 1 ATOM 2530 N N . TYR A 1 331 ? 6.555 153.846 7.148 1.00 10.86 ? 383 TYR A N 1 ATOM 2531 C CA . TYR A 1 331 ? 6.590 155.223 6.685 1.00 11.25 ? 383 TYR A CA 1 ATOM 2532 C C . TYR A 1 331 ? 6.631 155.212 5.162 1.00 10.26 ? 383 TYR A C 1 ATOM 2533 O O . TYR A 1 331 ? 7.549 154.677 4.560 1.00 11.00 ? 383 TYR A O 1 ATOM 2534 C CB . TYR A 1 331 ? 7.803 155.966 7.272 1.00 10.07 ? 383 TYR A CB 1 ATOM 2535 C CG . TYR A 1 331 ? 7.824 157.461 6.992 1.00 10.98 ? 383 TYR A CG 1 ATOM 2536 C CD1 . TYR A 1 331 ? 8.411 157.964 5.834 1.00 10.18 ? 383 TYR A CD1 1 ATOM 2537 C CD2 . TYR A 1 331 ? 7.253 158.363 7.881 1.00 9.69 ? 383 TYR A CD2 1 ATOM 2538 C CE1 . TYR A 1 331 ? 8.429 159.334 5.574 1.00 10.84 ? 383 TYR A CE1 1 ATOM 2539 C CE2 . TYR A 1 331 ? 7.266 159.728 7.628 1.00 9.70 ? 383 TYR A CE2 1 ATOM 2540 C CZ . TYR A 1 331 ? 7.850 160.204 6.475 1.00 10.24 ? 383 TYR A CZ 1 ATOM 2541 O OH . TYR A 1 331 ? 7.848 161.566 6.227 1.00 11.82 ? 383 TYR A OH 1 ATOM 2542 N N . VAL A 1 332 ? 5.610 155.809 4.559 1.00 12.05 ? 384 VAL A N 1 ATOM 2543 C CA . VAL A 1 332 ? 5.371 155.737 3.128 1.00 12.14 ? 384 VAL A CA 1 ATOM 2544 C C . VAL A 1 332 ? 5.322 157.136 2.539 1.00 13.24 ? 384 VAL A C 1 ATOM 2545 O O . VAL A 1 332 ? 4.524 157.950 2.980 1.00 14.49 ? 384 VAL A O 1 ATOM 2546 C CB . VAL A 1 332 ? 4.026 155.024 2.860 1.00 14.98 ? 384 VAL A CB 1 ATOM 2547 C CG1 . VAL A 1 332 ? 3.677 155.021 1.396 1.00 19.40 ? 384 VAL A CG1 1 ATOM 2548 C CG2 . VAL A 1 332 ? 4.072 153.601 3.418 1.00 16.80 ? 384 VAL A CG2 1 ATOM 2549 N N . THR A 1 333 ? 6.147 157.428 1.542 1.00 11.39 ? 385 THR A N 1 ATOM 2550 C CA . THR A 1 333 ? 6.026 158.714 0.869 1.00 11.75 ? 385 THR A CA 1 ATOM 2551 C C . THR A 1 333 ? 4.985 158.651 -0.248 1.00 14.16 ? 385 THR A C 1 ATOM 2552 O O . THR A 1 333 ? 4.601 157.575 -0.722 1.00 13.28 ? 385 THR A O 1 ATOM 2553 C CB . THR A 1 333 ? 7.367 159.202 0.296 1.00 12.92 ? 385 THR A CB 1 ATOM 2554 O OG1 . THR A 1 333 ? 7.723 158.436 -0.860 1.00 14.81 ? 385 THR A OG1 1 ATOM 2555 C CG2 . THR A 1 333 ? 8.469 159.102 1.344 1.00 14.53 ? 385 THR A CG2 1 ATOM 2556 N N . SER A 1 334 ? 4.531 159.822 -0.656 1.00 12.15 ? 386 SER A N 1 ATOM 2557 C CA . SER A 1 334 ? 3.505 159.936 -1.684 1.00 12.00 ? 386 SER A CA 1 ATOM 2558 C C . SER A 1 334 ? 3.997 159.334 -2.991 1.00 13.45 ? 386 SER A C 1 ATOM 2559 O O . SER A 1 334 ? 3.206 158.843 -3.800 1.00 15.80 ? 386 SER A O 1 ATOM 2560 C CB . SER A 1 334 ? 3.126 161.407 -1.865 1.00 13.18 ? 386 SER A CB 1 ATOM 2561 O OG . SER A 1 334 ? 1.950 161.572 -2.643 1.00 13.72 ? 386 SER A OG 1 ATOM 2562 N N . HIS A 1 335 ? 5.311 159.359 -3.184 1.00 11.14 ? 387 HIS A N 1 ATOM 2563 C CA . HIS A 1 335 ? 5.932 158.869 -4.404 1.00 13.47 ? 387 HIS A CA 1 ATOM 2564 C C . HIS A 1 335 ? 6.618 157.521 -4.165 1.00 12.38 ? 387 HIS A C 1 ATOM 2565 O O . HIS A 1 335 ? 7.815 157.355 -4.387 1.00 15.04 ? 387 HIS A O 1 ATOM 2566 C CB . HIS A 1 335 ? 6.921 159.911 -4.931 1.00 12.10 ? 387 HIS A CB 1 ATOM 2567 C CG . HIS A 1 335 ? 6.276 161.194 -5.367 1.00 12.62 ? 387 HIS A CG 1 ATOM 2568 N ND1 . HIS A 1 335 ? 6.329 162.352 -4.619 1.00 13.75 ? 387 HIS A ND1 1 ATOM 2569 C CD2 . HIS A 1 335 ? 5.572 161.500 -6.484 1.00 13.67 ? 387 HIS A CD2 1 ATOM 2570 C CE1 . HIS A 1 335 ? 5.683 163.315 -5.257 1.00 14.54 ? 387 HIS A CE1 1 ATOM 2571 N NE2 . HIS A 1 335 ? 5.210 162.821 -6.389 1.00 13.83 ? 387 HIS A NE2 1 ATOM 2572 N N . THR A 1 336 ? 5.836 156.555 -3.707 1.00 12.59 ? 388 THR A N 1 ATOM 2573 C CA . THR A 1 336 ? 6.316 155.197 -3.528 1.00 11.49 ? 388 THR A CA 1 ATOM 2574 C C . THR A 1 336 ? 6.307 154.478 -4.878 1.00 12.09 ? 388 THR A C 1 ATOM 2575 O O . THR A 1 336 ? 5.348 154.618 -5.641 1.00 14.18 ? 388 THR A O 1 ATOM 2576 C CB . THR A 1 336 ? 5.441 154.458 -2.508 1.00 13.21 ? 388 THR A CB 1 ATOM 2577 O OG1 . THR A 1 336 ? 5.592 155.078 -1.220 1.00 12.93 ? 388 THR A OG1 1 ATOM 2578 C CG2 . THR A 1 336 ? 5.816 152.990 -2.396 1.00 12.69 ? 388 THR A CG2 1 ATOM 2579 N N . ARG A 1 337 ? 7.353 153.714 -5.178 1.00 11.54 ? 389 ARG A N 1 ATOM 2580 C CA . ARG A 1 337 ? 7.453 153.066 -6.484 1.00 12.05 ? 389 ARG A CA 1 ATOM 2581 C C . ARG A 1 337 ? 6.579 151.803 -6.491 1.00 11.75 ? 389 ARG A C 1 ATOM 2582 O O . ARG A 1 337 ? 6.536 151.056 -5.517 1.00 12.88 ? 389 ARG A O 1 ATOM 2583 C CB . ARG A 1 337 ? 8.917 152.759 -6.850 1.00 12.43 ? 389 ARG A CB 1 ATOM 2584 C CG . ARG A 1 337 ? 9.727 151.896 -5.869 1.00 12.34 ? 389 ARG A CG 1 ATOM 2585 C CD . ARG A 1 337 ? 11.201 151.840 -6.282 1.00 12.99 ? 389 ARG A CD 1 ATOM 2586 N NE . ARG A 1 337 ? 11.336 151.389 -7.670 1.00 13.31 ? 389 ARG A NE 1 ATOM 2587 C CZ . ARG A 1 337 ? 12.349 151.671 -8.482 1.00 14.57 ? 389 ARG A CZ 1 ATOM 2588 N NH1 . ARG A 1 337 ? 13.379 152.407 -8.079 1.00 13.94 ? 389 ARG A NH1 1 ATOM 2589 N NH2 . ARG A 1 337 ? 12.332 151.202 -9.720 1.00 15.06 ? 389 ARG A NH2 1 ATOM 2590 N N . PRO A 1 338 ? 5.841 151.594 -7.588 1.00 13.77 ? 390 PRO A N 1 ATOM 2591 C CA . PRO A 1 338 ? 4.850 150.515 -7.636 1.00 15.48 ? 390 PRO A CA 1 ATOM 2592 C C . PRO A 1 338 ? 5.484 149.135 -7.757 1.00 16.38 ? 390 PRO A C 1 ATOM 2593 O O . PRO A 1 338 ? 4.805 148.123 -7.545 1.00 17.09 ? 390 PRO A O 1 ATOM 2594 C CB . PRO A 1 338 ? 4.025 150.862 -8.883 1.00 15.57 ? 390 PRO A CB 1 ATOM 2595 C CG . PRO A 1 338 ? 4.932 151.641 -9.734 1.00 19.69 ? 390 PRO A CG 1 ATOM 2596 C CD . PRO A 1 338 ? 5.797 152.437 -8.792 1.00 14.90 ? 390 PRO A CD 1 ATOM 2597 N N . ASP A 1 339 ? 6.772 149.105 -8.082 1.00 14.02 ? 391 ASP A N 1 ATOM 2598 C CA . ASP A 1 339 ? 7.533 147.863 -8.175 1.00 13.03 ? 391 ASP A CA 1 ATOM 2599 C C . ASP A 1 339 ? 8.359 147.637 -6.900 1.00 12.10 ? 391 ASP A C 1 ATOM 2600 O O . ASP A 1 339 ? 9.373 146.954 -6.930 1.00 13.48 ? 391 ASP A O 1 ATOM 2601 C CB . ASP A 1 339 ? 8.452 147.883 -9.410 1.00 13.98 ? 391 ASP A CB 1 ATOM 2602 C CG . ASP A 1 339 ? 9.316 149.133 -9.481 1.00 14.15 ? 391 ASP A CG 1 ATOM 2603 O OD1 . ASP A 1 339 ? 9.219 149.981 -8.567 1.00 14.77 ? 391 ASP A OD1 1 ATOM 2604 O OD2 . ASP A 1 339 ? 10.098 149.264 -10.442 1.00 15.86 ? 391 ASP A OD2 1 ATOM 2605 N N . HIS A 1 340 ? 7.916 148.190 -5.774 1.00 13.99 ? 392 HIS A N 1 ATOM 2606 C CA . HIS A 1 340 ? 8.753 148.183 -4.577 1.00 13.65 ? 392 HIS A CA 1 ATOM 2607 C C . HIS A 1 340 ? 9.043 146.776 -4.053 1.00 14.32 ? 392 HIS A C 1 ATOM 2608 O O . HIS A 1 340 ? 10.089 146.543 -3.458 1.00 14.77 ? 392 HIS A O 1 ATOM 2609 C CB . HIS A 1 340 ? 8.125 149.053 -3.467 1.00 14.52 ? 392 HIS A CB 1 ATOM 2610 C CG . HIS A 1 340 ? 6.863 148.497 -2.883 1.00 14.32 ? 392 HIS A CG 1 ATOM 2611 N ND1 . HIS A 1 340 ? 6.849 147.683 -1.769 1.00 16.51 ? 392 HIS A ND1 1 ATOM 2612 C CD2 . HIS A 1 340 ? 5.571 148.631 -3.266 1.00 15.75 ? 392 HIS A CD2 1 ATOM 2613 C CE1 . HIS A 1 340 ? 5.602 147.348 -1.487 1.00 19.11 ? 392 HIS A CE1 1 ATOM 2614 N NE2 . HIS A 1 340 ? 4.807 147.909 -2.380 1.00 19.78 ? 392 HIS A NE2 1 ATOM 2615 N N . GLU A 1 341 ? 8.148 145.820 -4.276 1.00 14.52 ? 393 GLU A N 1 ATOM 2616 C CA . GLU A 1 341 ? 8.411 144.464 -3.800 1.00 16.48 ? 393 GLU A CA 1 ATOM 2617 C C . GLU A 1 341 ? 9.663 143.854 -4.414 1.00 17.34 ? 393 GLU A C 1 ATOM 2618 O O . GLU A 1 341 ? 10.320 143.027 -3.777 1.00 16.76 ? 393 GLU A O 1 ATOM 2619 C CB . GLU A 1 341 ? 7.222 143.553 -4.083 1.00 19.08 ? 393 GLU A CB 1 ATOM 2620 C CG . GLU A 1 341 ? 5.996 143.921 -3.279 1.00 24.91 ? 393 GLU A CG 1 ATOM 2621 C CD . GLU A 1 341 ? 5.113 144.930 -3.979 1.00 28.55 ? 393 GLU A CD 1 ATOM 2622 O OE1 . GLU A 1 341 ? 5.565 145.563 -4.964 1.00 29.39 ? 393 GLU A OE1 1 ATOM 2623 O OE2 . GLU A 1 341 ? 3.950 145.079 -3.543 1.00 40.06 ? 393 GLU A OE2 1 ATOM 2624 N N . THR A 1 342 ? 10.007 144.261 -5.633 1.00 12.95 ? 394 THR A N 1 ATOM 2625 C CA . THR A 1 342 ? 11.170 143.701 -6.314 1.00 13.93 ? 394 THR A CA 1 ATOM 2626 C C . THR A 1 342 ? 12.334 144.680 -6.377 1.00 12.81 ? 394 THR A C 1 ATOM 2627 O O . THR A 1 342 ? 13.415 144.316 -6.823 1.00 15.25 ? 394 THR A O 1 ATOM 2628 C CB . THR A 1 342 ? 10.834 143.251 -7.760 1.00 17.14 ? 394 THR A CB 1 ATOM 2629 O OG1 . THR A 1 342 ? 10.313 144.353 -8.514 1.00 17.55 ? 394 THR A OG1 1 ATOM 2630 C CG2 . THR A 1 342 ? 9.820 142.121 -7.739 1.00 17.97 ? 394 THR A CG2 1 ATOM 2631 N N . LYS A 1 343 ? 12.116 145.910 -5.917 1.00 12.21 ? 395 LYS A N 1 ATOM 2632 C CA . LYS A 1 343 ? 13.130 146.965 -5.993 1.00 11.73 ? 395 LYS A CA 1 ATOM 2633 C C . LYS A 1 343 ? 13.596 147.447 -4.623 1.00 14.43 ? 395 LYS A C 1 ATOM 2634 O O . LYS A 1 343 ? 14.590 148.178 -4.529 1.00 13.86 ? 395 LYS A O 1 ATOM 2635 C CB . LYS A 1 343 ? 12.598 148.161 -6.792 1.00 13.36 ? 395 LYS A CB 1 ATOM 2636 C CG . LYS A 1 343 ? 12.509 147.920 -8.289 1.00 14.92 ? 395 LYS A CG 1 ATOM 2637 C CD . LYS A 1 343 ? 13.889 147.941 -8.938 1.00 18.53 ? 395 LYS A CD 1 ATOM 2638 C CE . LYS A 1 343 ? 13.816 147.725 -10.428 1.00 24.29 ? 395 LYS A CE 1 ATOM 2639 N NZ . LYS A 1 343 ? 15.183 147.751 -11.026 1.00 22.38 ? 395 LYS A NZ 1 ATOM 2640 N N . CYS A 1 344 ? 12.884 147.044 -3.574 1.00 12.37 ? 396 CYS A N 1 ATOM 2641 C CA . CYS A 1 344 ? 13.135 147.534 -2.216 1.00 11.01 ? 396 CYS A CA 1 ATOM 2642 C C . CYS A 1 344 ? 13.201 146.386 -1.222 1.00 13.53 ? 396 CYS A C 1 ATOM 2643 O O . CYS A 1 344 ? 12.658 145.314 -1.481 1.00 13.38 ? 396 CYS A O 1 ATOM 2644 C CB . CYS A 1 344 ? 12.040 148.506 -1.780 1.00 12.36 ? 396 CYS A CB 1 ATOM 2645 S SG . CYS A 1 344 ? 11.765 149.875 -2.887 1.00 14.08 ? 396 CYS A SG 1 ATOM 2646 N N . PRO A 1 345 ? 13.841 146.611 -0.063 1.00 11.28 ? 397 PRO A N 1 ATOM 2647 C CA . PRO A 1 345 ? 13.909 145.529 0.918 1.00 12.68 ? 397 PRO A CA 1 ATOM 2648 C C . PRO A 1 345 ? 12.556 145.215 1.550 1.00 12.29 ? 397 PRO A C 1 ATOM 2649 O O . PRO A 1 345 ? 11.692 146.088 1.665 1.00 12.48 ? 397 PRO A O 1 ATOM 2650 C CB . PRO A 1 345 ? 14.889 146.069 1.974 1.00 15.05 ? 397 PRO A CB 1 ATOM 2651 C CG . PRO A 1 345 ? 15.617 147.171 1.295 1.00 13.48 ? 397 PRO A CG 1 ATOM 2652 C CD . PRO A 1 345 ? 14.651 147.774 0.351 1.00 12.44 ? 397 PRO A CD 1 ATOM 2653 N N . PRO A 1 346 ? 12.371 143.964 1.972 1.00 12.53 ? 398 PRO A N 1 ATOM 2654 C CA . PRO A 1 346 ? 11.156 143.574 2.684 1.00 14.60 ? 398 PRO A CA 1 ATOM 2655 C C . PRO A 1 346 ? 11.167 144.071 4.127 1.00 13.18 ? 398 PRO A C 1 ATOM 2656 O O . PRO A 1 346 ? 12.168 144.602 4.614 1.00 14.09 ? 398 PRO A O 1 ATOM 2657 C CB . PRO A 1 346 ? 11.211 142.053 2.621 1.00 14.02 ? 398 PRO A CB 1 ATOM 2658 C CG . PRO A 1 346 ? 12.669 141.770 2.704 1.00 15.35 ? 398 PRO A CG 1 ATOM 2659 C CD . PRO A 1 346 ? 13.326 142.846 1.882 1.00 13.39 ? 398 PRO A CD 1 ATOM 2660 N N . ARG A 1 347 ? 10.045 143.890 4.802 1.00 12.38 ? 399 ARG A N 1 ATOM 2661 C CA . ARG A 1 347 ? 9.877 144.338 6.172 1.00 13.40 ? 399 ARG A CA 1 ATOM 2662 C C . ARG A 1 347 ? 10.800 143.636 7.149 1.00 12.60 ? 399 ARG A C 1 ATOM 2663 O O . ARG A 1 347 ? 11.368 144.267 8.039 1.00 12.05 ? 399 ARG A O 1 ATOM 2664 C CB . ARG A 1 347 ? 8.425 144.126 6.597 1.00 13.73 ? 399 ARG A CB 1 ATOM 2665 C CG . ARG A 1 347 ? 8.102 144.564 8.003 1.00 15.04 ? 399 ARG A CG 1 ATOM 2666 C CD . ARG A 1 347 ? 6.624 144.414 8.273 1.00 21.55 ? 399 ARG A CD 1 ATOM 2667 N NE . ARG A 1 347 ? 6.292 143.013 8.453 1.00 23.03 ? 399 ARG A NE 1 ATOM 2668 C CZ . ARG A 1 347 ? 6.053 142.430 9.623 1.00 24.94 ? 399 ARG A CZ 1 ATOM 2669 N NH1 . ARG A 1 347 ? 6.076 143.121 10.754 1.00 26.12 ? 399 ARG A NH1 1 ATOM 2670 N NH2 . ARG A 1 347 ? 5.774 141.138 9.657 1.00 27.61 ? 399 ARG A NH2 1 ATOM 2671 N N . GLU A 1 348 ? 10.941 142.328 6.998 1.00 11.90 ? 400 GLU A N 1 ATOM 2672 C CA . GLU A 1 348 ? 11.622 141.537 8.007 1.00 11.45 ? 400 GLU A CA 1 ATOM 2673 C C . GLU A 1 348 ? 13.131 141.492 7.815 1.00 10.01 ? 400 GLU A C 1 ATOM 2674 O O . GLU A 1 348 ? 13.610 141.420 6.686 1.00 11.31 ? 400 GLU A O 1 ATOM 2675 C CB . GLU A 1 348 ? 11.096 140.107 7.998 1.00 11.67 ? 400 GLU A CB 1 ATOM 2676 C CG . GLU A 1 348 ? 9.576 139.983 8.114 1.00 16.31 ? 400 GLU A CG 1 ATOM 2677 C CD . GLU A 1 348 ? 8.840 140.014 6.778 1.00 19.29 ? 400 GLU A CD 1 ATOM 2678 O OE1 . GLU A 1 348 ? 9.457 140.293 5.728 1.00 15.85 ? 400 GLU A OE1 1 ATOM 2679 O OE2 . GLU A 1 348 ? 7.618 139.735 6.784 1.00 23.15 ? 400 GLU A OE2 1 ATOM 2680 N N . PRO A 1 349 ? 13.885 141.501 8.925 1.00 11.08 ? 401 PRO A N 1 ATOM 2681 C CA . PRO A 1 349 ? 15.300 141.163 8.791 1.00 11.50 ? 401 PRO A CA 1 ATOM 2682 C C . PRO A 1 349 ? 15.469 139.764 8.235 1.00 10.38 ? 401 PRO A C 1 ATOM 2683 O O . PRO A 1 349 ? 14.511 138.986 8.257 1.00 12.67 ? 401 PRO A O 1 ATOM 2684 C CB . PRO A 1 349 ? 15.832 141.258 10.229 1.00 13.20 ? 401 PRO A CB 1 ATOM 2685 C CG . PRO A 1 349 ? 14.854 142.055 10.963 1.00 13.60 ? 401 PRO A CG 1 ATOM 2686 C CD . PRO A 1 349 ? 13.524 141.793 10.319 1.00 11.34 ? 401 PRO A CD 1 ATOM 2687 N N . LEU A 1 350 ? 16.666 139.445 7.752 1.00 10.58 ? 402 LEU A N 1 ATOM 2688 C CA . LEU A 1 350 ? 16.916 138.144 7.153 1.00 10.91 ? 402 LEU A CA 1 ATOM 2689 C C . LEU A 1 350 ? 17.680 137.269 8.145 1.00 11.95 ? 402 LEU A C 1 ATOM 2690 O O . LEU A 1 350 ? 18.829 137.554 8.493 1.00 12.39 ? 402 LEU A O 1 ATOM 2691 C CB . LEU A 1 350 ? 17.684 138.297 5.843 1.00 11.16 ? 402 LEU A CB 1 ATOM 2692 C CG . LEU A 1 350 ? 17.095 139.270 4.817 1.00 12.91 ? 402 LEU A CG 1 ATOM 2693 C CD1 . LEU A 1 350 ? 18.052 139.431 3.665 1.00 16.63 ? 402 LEU A CD1 1 ATOM 2694 C CD2 . LEU A 1 350 ? 15.723 138.782 4.347 1.00 14.47 ? 402 LEU A CD2 1 ATOM 2695 N N . LYS A 1 351 ? 17.050 136.191 8.609 1.00 11.45 ? 403 LYS A N 1 ATOM 2696 C CA . LYS A 1 351 ? 17.693 135.343 9.595 1.00 12.07 ? 403 LYS A CA 1 ATOM 2697 C C . LYS A 1 351 ? 18.739 134.435 8.962 1.00 12.03 ? 403 LYS A C 1 ATOM 2698 O O . LYS A 1 351 ? 18.611 134.000 7.811 1.00 12.66 ? 403 LYS A O 1 ATOM 2699 C CB . LYS A 1 351 ? 16.660 134.498 10.355 1.00 12.21 ? 403 LYS A CB 1 ATOM 2700 C CG . LYS A 1 351 ? 15.947 133.447 9.527 1.00 15.23 ? 403 LYS A CG 1 ATOM 2701 C CD . LYS A 1 351 ? 15.130 132.533 10.435 1.00 15.46 ? 403 LYS A CD 1 ATOM 2702 C CE . LYS A 1 351 ? 14.412 131.459 9.636 1.00 16.27 ? 403 LYS A CE 1 ATOM 2703 N NZ . LYS A 1 351 ? 13.717 130.503 10.536 1.00 19.97 ? 403 LYS A NZ 1 ATOM 2704 N N . ASN A 1 352 ? 19.794 134.195 9.731 1.00 12.97 ? 404 ASN A N 1 ATOM 2705 C CA . ASN A 1 352 ? 20.780 133.170 9.434 1.00 14.31 ? 404 ASN A CA 1 ATOM 2706 C C . ASN A 1 352 ? 21.539 133.401 8.138 1.00 14.77 ? 404 ASN A C 1 ATOM 2707 O O . ASN A 1 352 ? 21.951 132.453 7.484 1.00 15.27 ? 404 ASN A O 1 ATOM 2708 C CB . ASN A 1 352 ? 20.102 131.791 9.404 1.00 14.03 ? 404 ASN A CB 1 ATOM 2709 C CG . ASN A 1 352 ? 19.535 131.391 10.750 1.00 16.20 ? 404 ASN A CG 1 ATOM 2710 O OD1 . ASN A 1 352 ? 18.331 131.183 10.890 1.00 17.56 ? 404 ASN A OD1 1 ATOM 2711 N ND2 . ASN A 1 352 ? 20.403 131.284 11.754 1.00 18.87 ? 404 ASN A ND2 1 ATOM 2712 N N . VAL A 1 353 ? 21.753 134.667 7.778 1.00 12.03 ? 405 VAL A N 1 ATOM 2713 C CA . VAL A 1 353 ? 22.567 134.976 6.613 1.00 11.48 ? 405 VAL A CA 1 ATOM 2714 C C . VAL A 1 353 ? 23.458 136.181 6.863 1.00 10.99 ? 405 VAL A C 1 ATOM 2715 O O . VAL A 1 353 ? 23.212 136.968 7.781 1.00 13.30 ? 405 VAL A O 1 ATOM 2716 C CB . VAL A 1 353 ? 21.713 135.228 5.351 1.00 11.81 ? 405 VAL A CB 1 ATOM 2717 C CG1 . VAL A 1 353 ? 21.120 133.902 4.830 1.00 14.65 ? 405 VAL A CG1 1 ATOM 2718 C CG2 . VAL A 1 353 ? 20.615 136.256 5.625 1.00 12.80 ? 405 VAL A CG2 1 ATOM 2719 N N . ARG A 1 354 ? 24.492 136.274 6.030 1.00 12.64 ? 406 ARG A N 1 ATOM 2720 C CA . ARG A 1 354 ? 25.490 137.351 6.060 1.00 12.31 ? 406 ARG A CA 1 ATOM 2721 C C . ARG A 1 354 ? 25.587 138.008 4.678 1.00 15.81 ? 406 ARG A C 1 ATOM 2722 O O . ARG A 1 354 ? 25.659 137.302 3.670 1.00 14.05 ? 406 ARG A O 1 ATOM 2723 C CB . ARG A 1 354 ? 26.869 136.803 6.448 1.00 16.74 ? 406 ARG A CB 1 ATOM 2724 C CG . ARG A 1 354 ? 26.920 135.952 7.698 1.00 13.78 ? 406 ARG A CG 1 ATOM 2725 C CD . ARG A 1 354 ? 28.073 134.948 7.643 1.00 15.57 ? 406 ARG A CD 1 ATOM 2726 N NE . ARG A 1 354 ? 29.379 135.593 7.536 1.00 20.20 ? 406 ARG A NE 1 ATOM 2727 C CZ . ARG A 1 354 ? 30.505 134.956 7.227 1.00 19.92 ? 406 ARG A CZ 1 ATOM 2728 N NH1 . ARG A 1 354 ? 30.494 133.651 6.972 1.00 21.98 ? 406 ARG A NH1 1 ATOM 2729 N NH2 . ARG A 1 354 ? 31.648 135.624 7.158 1.00 21.74 ? 406 ARG A NH2 1 ATOM 2730 N N . TRP A 1 355 ? 25.618 139.340 4.606 1.00 11.90 ? 407 TRP A N 1 ATOM 2731 C CA . TRP A 1 355 ? 25.781 140.019 3.315 1.00 11.52 ? 407 TRP A CA 1 ATOM 2732 C C . TRP A 1 355 ? 27.113 139.690 2.656 1.00 14.25 ? 407 TRP A C 1 ATOM 2733 O O . TRP A 1 355 ? 28.150 139.705 3.316 1.00 14.43 ? 407 TRP A O 1 ATOM 2734 C CB . TRP A 1 355 ? 25.699 141.544 3.469 1.00 9.47 ? 407 TRP A CB 1 ATOM 2735 C CG . TRP A 1 355 ? 24.418 142.055 4.049 1.00 11.72 ? 407 TRP A CG 1 ATOM 2736 C CD1 . TRP A 1 355 ? 24.232 142.573 5.297 1.00 11.98 ? 407 TRP A CD1 1 ATOM 2737 C CD2 . TRP A 1 355 ? 23.144 142.113 3.397 1.00 12.27 ? 407 TRP A CD2 1 ATOM 2738 N NE1 . TRP A 1 355 ? 22.924 142.941 5.467 1.00 11.95 ? 407 TRP A NE1 1 ATOM 2739 C CE2 . TRP A 1 355 ? 22.234 142.674 4.314 1.00 12.33 ? 407 TRP A CE2 1 ATOM 2740 C CE3 . TRP A 1 355 ? 22.688 141.748 2.128 1.00 11.58 ? 407 TRP A CE3 1 ATOM 2741 C CZ2 . TRP A 1 355 ? 20.889 142.862 4.010 1.00 10.66 ? 407 TRP A CZ2 1 ATOM 2742 C CZ3 . TRP A 1 355 ? 21.358 141.937 1.824 1.00 13.19 ? 407 TRP A CZ3 1 ATOM 2743 C CH2 . TRP A 1 355 ? 20.470 142.488 2.760 1.00 12.42 ? 407 TRP A CH2 1 ATOM 2744 N N . GLY A 1 356 ? 27.091 139.443 1.351 1.00 12.90 ? 408 GLY A N 1 ATOM 2745 C CA . GLY A 1 356 ? 28.319 139.193 0.616 1.00 14.53 ? 408 GLY A CA 1 ATOM 2746 C C . GLY A 1 356 ? 28.300 139.683 -0.816 1.00 11.85 ? 408 GLY A C 1 ATOM 2747 O O . GLY A 1 356 ? 27.317 140.264 -1.289 1.00 12.67 ? 408 GLY A O 1 ATOM 2748 N N . VAL A 1 357 ? 29.416 139.452 -1.504 1.00 14.19 ? 409 VAL A N 1 ATOM 2749 C CA . VAL A 1 357 ? 29.527 139.697 -2.941 1.00 14.79 ? 409 VAL A CA 1 ATOM 2750 C C . VAL A 1 357 ? 30.034 138.407 -3.587 1.00 16.23 ? 409 VAL A C 1 ATOM 2751 O O . VAL A 1 357 ? 30.637 137.577 -2.920 1.00 17.39 ? 409 VAL A O 1 ATOM 2752 C CB . VAL A 1 357 ? 30.469 140.880 -3.263 1.00 16.37 ? 409 VAL A CB 1 ATOM 2753 C CG1 . VAL A 1 357 ? 29.888 142.185 -2.713 1.00 16.57 ? 409 VAL A CG1 1 ATOM 2754 C CG2 . VAL A 1 357 ? 31.871 140.627 -2.717 1.00 19.65 ? 409 VAL A CG2 1 ATOM 2755 N N . VAL A 1 358 ? 29.771 138.229 -4.875 1.00 17.94 ? 410 VAL A N 1 ATOM 2756 C CA . VAL A 1 358 ? 30.110 136.974 -5.528 1.00 18.22 ? 410 VAL A CA 1 ATOM 2757 C C . VAL A 1 358 ? 31.626 136.851 -5.651 1.00 19.52 ? 410 VAL A C 1 ATOM 2758 O O . VAL A 1 358 ? 32.323 137.832 -5.916 1.00 23.22 ? 410 VAL A O 1 ATOM 2759 C CB . VAL A 1 358 ? 29.444 136.859 -6.913 1.00 21.42 ? 410 VAL A CB 1 ATOM 2760 C CG1 . VAL A 1 358 ? 29.923 135.612 -7.650 1.00 21.13 ? 410 VAL A CG1 1 ATOM 2761 C CG2 . VAL A 1 358 ? 27.925 136.811 -6.766 1.00 19.70 ? 410 VAL A CG2 1 ATOM 2762 N N . SER A 1 359 ? 32.116 135.641 -5.419 1.00 20.76 ? 411 SER A N 1 ATOM 2763 C CA . SER A 1 359 ? 33.532 135.336 -5.555 1.00 20.10 ? 411 SER A CA 1 ATOM 2764 C C . SER A 1 359 ? 33.698 134.083 -6.407 1.00 23.45 ? 411 SER A C 1 ATOM 2765 O O . SER A 1 359 ? 33.097 133.051 -6.121 1.00 20.44 ? 411 SER A O 1 ATOM 2766 C CB . SER A 1 359 ? 34.172 135.146 -4.182 1.00 23.02 ? 411 SER A CB 1 ATOM 2767 O OG . SER A 1 359 ? 35.557 134.868 -4.296 1.00 26.79 ? 411 SER A OG 1 ATOM 2768 N N . LYS A 1 360 ? 34.491 134.196 -7.468 1.00 25.36 ? 412 LYS A N 1 ATOM 2769 C CA . LYS A 1 360 ? 34.785 133.069 -8.354 1.00 30.07 ? 412 LYS A CA 1 ATOM 2770 C C . LYS A 1 360 ? 33.525 132.387 -8.881 1.00 29.83 ? 412 LYS A C 1 ATOM 2771 O O . LYS A 1 360 ? 33.435 131.159 -8.903 1.00 29.73 ? 412 LYS A O 1 ATOM 2772 C CB . LYS A 1 360 ? 35.663 132.048 -7.632 1.00 29.74 ? 412 LYS A CB 1 ATOM 2773 C CG . LYS A 1 360 ? 36.997 132.609 -7.160 1.00 32.35 ? 412 LYS A CG 1 ATOM 2774 C CD . LYS A 1 360 ? 37.558 131.806 -6.003 1.00 36.07 ? 412 LYS A CD 1 ATOM 2775 C CE . LYS A 1 360 ? 38.725 132.524 -5.341 1.00 44.25 ? 412 LYS A CE 1 ATOM 2776 N NZ . LYS A 1 360 ? 39.935 132.520 -6.202 1.00 50.04 ? 412 LYS A NZ 1 ATOM 2777 N N . GLY A 1 361 ? 32.552 133.193 -9.290 1.00 29.09 ? 413 GLY A N 1 ATOM 2778 C CA . GLY A 1 361 ? 31.390 132.696 -10.003 1.00 30.53 ? 413 GLY A CA 1 ATOM 2779 C C . GLY A 1 361 ? 30.289 132.071 -9.167 1.00 26.01 ? 413 GLY A C 1 ATOM 2780 O O . GLY A 1 361 ? 29.128 132.460 -9.294 1.00 28.06 ? 413 GLY A O 1 ATOM 2781 N N . LYS A 1 362 ? 30.637 131.097 -8.326 1.00 24.39 ? 414 LYS A N 1 ATOM 2782 C CA . LYS A 1 362 ? 29.624 130.308 -7.623 1.00 26.39 ? 414 LYS A CA 1 ATOM 2783 C C . LYS A 1 362 ? 29.813 130.306 -6.107 1.00 23.15 ? 414 LYS A C 1 ATOM 2784 O O . LYS A 1 362 ? 29.223 129.486 -5.407 1.00 23.99 ? 414 LYS A O 1 ATOM 2785 C CB . LYS A 1 362 ? 29.622 128.867 -8.159 1.00 32.32 ? 414 LYS A CB 1 ATOM 2786 C CG . LYS A 1 362 ? 30.925 128.440 -8.812 1.00 42.73 ? 414 LYS A CG 1 ATOM 2787 C CD . LYS A 1 362 ? 30.929 126.950 -9.152 1.00 45.57 ? 414 LYS A CD 1 ATOM 2788 C CE . LYS A 1 362 ? 31.141 126.091 -7.913 1.00 45.98 ? 414 LYS A CE 1 ATOM 2789 N NZ . LYS A 1 362 ? 31.550 124.703 -8.267 1.00 51.69 ? 414 LYS A NZ 1 ATOM 2790 N N . TYR A 1 363 ? 30.613 131.243 -5.601 1.00 24.26 ? 415 TYR A N 1 ATOM 2791 C CA . TYR A 1 363 ? 30.804 131.387 -4.161 1.00 20.23 ? 415 TYR A CA 1 ATOM 2792 C C . TYR A 1 363 ? 30.481 132.809 -3.740 1.00 17.90 ? 415 TYR A C 1 ATOM 2793 O O . TYR A 1 363 ? 30.273 133.685 -4.578 1.00 17.30 ? 415 TYR A O 1 ATOM 2794 C CB . TYR A 1 363 ? 32.228 131.012 -3.757 1.00 21.42 ? 415 TYR A CB 1 ATOM 2795 C CG . TYR A 1 363 ? 32.561 129.572 -4.085 1.00 25.58 ? 415 TYR A CG 1 ATOM 2796 C CD1 . TYR A 1 363 ? 32.300 128.561 -3.175 1.00 30.48 ? 415 TYR A CD1 1 ATOM 2797 C CD2 . TYR A 1 363 ? 33.112 129.225 -5.312 1.00 32.71 ? 415 TYR A CD2 1 ATOM 2798 C CE1 . TYR A 1 363 ? 32.587 127.241 -3.469 1.00 30.63 ? 415 TYR A CE1 1 ATOM 2799 C CE2 . TYR A 1 363 ? 33.404 127.903 -5.614 1.00 33.69 ? 415 TYR A CE2 1 ATOM 2800 C CZ . TYR A 1 363 ? 33.135 126.919 -4.687 1.00 31.08 ? 415 TYR A CZ 1 ATOM 2801 O OH . TYR A 1 363 ? 33.417 125.601 -4.972 1.00 41.02 ? 415 TYR A OH 1 ATOM 2802 N N . CYS A 1 364 ? 30.405 133.007 -2.431 1.00 18.60 ? 416 CYS A N 1 ATOM 2803 C CA . CYS A 1 364 ? 30.084 134.300 -1.853 1.00 18.44 ? 416 CYS A CA 1 ATOM 2804 C C . CYS A 1 364 ? 31.139 134.599 -0.801 1.00 18.49 ? 416 CYS A C 1 ATOM 2805 O O . CYS A 1 364 ? 31.499 133.725 -0.021 1.00 18.89 ? 416 CYS A O 1 ATOM 2806 C CB . CYS A 1 364 ? 28.674 134.285 -1.248 1.00 18.71 ? 416 CYS A CB 1 ATOM 2807 S SG . CYS A 1 364 ? 27.997 135.909 -0.784 1.00 19.90 ? 416 CYS A SG 1 ATOM 2808 N N . LYS A 1 365 ? 31.666 135.818 -0.806 1.00 16.61 ? 417 LYS A N 1 ATOM 2809 C CA . LYS A 1 365 ? 32.556 136.255 0.260 1.00 21.16 ? 417 LYS A CA 1 ATOM 2810 C C . LYS A 1 365 ? 31.917 137.432 0.989 1.00 16.91 ? 417 LYS A C 1 ATOM 2811 O O . LYS A 1 365 ? 31.197 138.229 0.381 1.00 16.02 ? 417 LYS A O 1 ATOM 2812 C CB . LYS A 1 365 ? 33.936 136.629 -0.293 1.00 20.88 ? 417 LYS A CB 1 ATOM 2813 C CG . LYS A 1 365 ? 33.926 137.736 -1.329 1.00 22.16 ? 417 LYS A CG 1 ATOM 2814 C CD . LYS A 1 365 ? 35.335 138.023 -1.847 1.00 25.83 ? 417 LYS A CD 1 ATOM 2815 C CE . LYS A 1 365 ? 35.324 139.107 -2.906 1.00 28.99 ? 417 LYS A CE 1 ATOM 2816 N NZ . LYS A 1 365 ? 36.687 139.342 -3.469 1.00 41.37 ? 417 LYS A NZ 1 ATOM 2817 N N . PRO A 1 366 ? 32.153 137.527 2.304 1.00 17.08 ? 418 PRO A N 1 ATOM 2818 C CA . PRO A 1 366 ? 31.514 138.620 3.033 1.00 17.17 ? 418 PRO A CA 1 ATOM 2819 C C . PRO A 1 366 ? 32.003 139.960 2.532 1.00 19.57 ? 418 PRO A C 1 ATOM 2820 O O . PRO A 1 366 ? 33.142 140.096 2.066 1.00 18.17 ? 418 PRO A O 1 ATOM 2821 C CB . PRO A 1 366 ? 31.922 138.371 4.489 1.00 17.24 ? 418 PRO A CB 1 ATOM 2822 C CG . PRO A 1 366 ? 33.114 137.491 4.416 1.00 26.03 ? 418 PRO A CG 1 ATOM 2823 C CD . PRO A 1 366 ? 32.931 136.652 3.196 1.00 19.97 ? 418 PRO A CD 1 ATOM 2824 N N . MET A 1 367 ? 31.126 140.947 2.602 1.00 18.13 ? 419 MET A N 1 ATOM 2825 C CA . MET A 1 367 ? 31.496 142.292 2.222 1.00 18.20 ? 419 MET A CA 1 ATOM 2826 C C . MET A 1 367 ? 32.521 142.805 3.230 1.00 15.97 ? 419 MET A C 1 ATOM 2827 O O . MET A 1 367 ? 32.659 142.251 4.321 1.00 17.16 ? 419 MET A O 1 ATOM 2828 C CB . MET A 1 367 ? 30.259 143.192 2.167 1.00 17.64 ? 419 MET A CB 1 ATOM 2829 C CG . MET A 1 367 ? 29.150 142.655 1.253 1.00 18.86 ? 419 MET A CG 1 ATOM 2830 S SD . MET A 1 367 ? 28.059 143.921 0.569 1.00 20.68 ? 419 MET A SD 1 ATOM 2831 C CE . MET A 1 367 ? 27.247 144.527 2.036 1.00 18.33 ? 419 MET A CE 1 ATOM 2832 N N . ASN A 1 368 ? 33.240 143.852 2.846 1.00 19.27 ? 420 ASN A N 1 ATOM 2833 C CA . ASN A 1 368 ? 34.229 144.469 3.717 1.00 18.37 ? 420 ASN A CA 1 ATOM 2834 C C . ASN A 1 368 ? 33.577 145.521 4.600 1.00 14.23 ? 420 ASN A C 1 ATOM 2835 O O . ASN A 1 368 ? 33.064 146.524 4.097 1.00 14.79 ? 420 ASN A O 1 ATOM 2836 C CB . ASN A 1 368 ? 35.350 145.103 2.894 1.00 21.87 ? 420 ASN A CB 1 ATOM 2837 C CG . ASN A 1 368 ? 36.161 144.079 2.118 1.00 27.94 ? 420 ASN A CG 1 ATOM 2838 O OD1 . ASN A 1 368 ? 36.443 142.990 2.613 1.00 29.95 ? 420 ASN A OD1 1 ATOM 2839 N ND2 . ASN A 1 368 ? 36.542 144.431 0.894 1.00 32.49 ? 420 ASN A ND2 1 ATOM 2840 N N . ALA A 1 369 ? 33.616 145.295 5.910 1.00 14.68 ? 421 ALA A N 1 ATOM 2841 C CA . ALA A 1 369 ? 32.987 146.196 6.864 1.00 15.40 ? 421 ALA A CA 1 ATOM 2842 C C . ALA A 1 369 ? 33.647 147.563 6.819 1.00 15.03 ? 421 ALA A C 1 ATOM 2843 O O . ALA A 1 369 ? 34.869 147.671 6.736 1.00 15.15 ? 421 ALA A O 1 ATOM 2844 C CB . ALA A 1 369 ? 33.056 145.622 8.277 1.00 16.07 ? 421 ALA A CB 1 ATOM 2845 N N . ARG A 1 370 ? 32.820 148.597 6.852 1.00 12.72 ? 422 ARG A N 1 ATOM 2846 C CA . ARG A 1 370 ? 33.281 149.967 7.034 1.00 13.32 ? 422 ARG A CA 1 ATOM 2847 C C . ARG A 1 370 ? 33.535 150.249 8.504 1.00 14.93 ? 422 ARG A C 1 ATOM 2848 O O . ARG A 1 370 ? 34.400 151.057 8.864 1.00 12.73 ? 422 ARG A O 1 ATOM 2849 C CB . ARG A 1 370 ? 32.241 150.957 6.513 1.00 11.43 ? 422 ARG A CB 1 ATOM 2850 C CG . ARG A 1 370 ? 31.900 150.823 5.036 1.00 16.28 ? 422 ARG A CG 1 ATOM 2851 C CD . ARG A 1 370 ? 33.064 151.162 4.122 1.00 19.54 ? 422 ARG A CD 1 ATOM 2852 N NE . ARG A 1 370 ? 33.676 152.443 4.477 1.00 22.76 ? 422 ARG A NE 1 ATOM 2853 C CZ . ARG A 1 370 ? 33.189 153.637 4.144 1.00 30.57 ? 422 ARG A CZ 1 ATOM 2854 N NH1 . ARG A 1 370 ? 32.070 153.742 3.438 1.00 26.07 ? 422 ARG A NH1 1 ATOM 2855 N NH2 . ARG A 1 370 ? 33.828 154.739 4.524 1.00 35.21 ? 422 ARG A NH2 1 ATOM 2856 N N . ALA A 1 371 ? 32.751 149.601 9.352 1.00 12.27 ? 423 ALA A N 1 ATOM 2857 C CA . ALA A 1 371 ? 32.734 149.882 10.770 1.00 12.21 ? 423 ALA A CA 1 ATOM 2858 C C . ALA A 1 371 ? 32.085 148.735 11.521 1.00 13.22 ? 423 ALA A C 1 ATOM 2859 O O . ALA A 1 371 ? 31.376 147.915 10.923 1.00 13.32 ? 423 ALA A O 1 ATOM 2860 C CB . ALA A 1 371 ? 31.989 151.181 11.053 1.00 14.24 ? 423 ALA A CB 1 ATOM 2861 N N . SER A 1 372 ? 32.315 148.677 12.827 1.00 11.72 ? 424 SER A N 1 ATOM 2862 C CA . SER A 1 372 ? 31.636 147.694 13.662 1.00 12.68 ? 424 SER A CA 1 ATOM 2863 C C . SER A 1 372 ? 31.272 148.262 15.023 1.00 14.80 ? 424 SER A C 1 ATOM 2864 O O . SER A 1 372 ? 31.852 149.252 15.481 1.00 14.25 ? 424 SER A O 1 ATOM 2865 C CB . SER A 1 372 ? 32.491 146.430 13.832 1.00 14.98 ? 424 SER A CB 1 ATOM 2866 O OG . SER A 1 372 ? 33.598 146.650 14.692 1.00 15.29 ? 424 SER A OG 1 ATOM 2867 N N . LEU A 1 373 ? 30.289 147.626 15.653 1.00 13.07 ? 425 LEU A N 1 ATOM 2868 C CA . LEU A 1 373 ? 29.817 147.986 16.980 1.00 11.25 ? 425 LEU A CA 1 ATOM 2869 C C . LEU A 1 373 ? 29.818 146.706 17.801 1.00 15.24 ? 425 LEU A C 1 ATOM 2870 O O . LEU A 1 373 ? 29.229 145.707 17.382 1.00 17.33 ? 425 LEU A O 1 ATOM 2871 C CB . LEU A 1 373 ? 28.416 148.614 16.915 1.00 12.19 ? 425 LEU A CB 1 ATOM 2872 C CG . LEU A 1 373 ? 27.776 149.107 18.207 1.00 20.03 ? 425 LEU A CG 1 ATOM 2873 C CD1 . LEU A 1 373 ? 28.505 150.332 18.727 1.00 20.90 ? 425 LEU A CD1 1 ATOM 2874 C CD2 . LEU A 1 373 ? 26.313 149.433 17.962 1.00 21.69 ? 425 LEU A CD2 1 ATOM 2875 N N . SER A 1 374 ? 30.474 146.720 18.956 1.00 14.41 ? 426 SER A N 1 ATOM 2876 C CA . SER A 1 374 ? 30.590 145.517 19.780 1.00 14.08 ? 426 SER A CA 1 ATOM 2877 C C . SER A 1 374 ? 29.555 145.462 20.905 1.00 17.01 ? 426 SER A C 1 ATOM 2878 O O . SER A 1 374 ? 29.043 146.481 21.356 1.00 17.18 ? 426 SER A O 1 ATOM 2879 C CB . SER A 1 374 ? 32.003 145.427 20.370 1.00 16.78 ? 426 SER A CB 1 ATOM 2880 O OG . SER A 1 374 ? 32.962 145.159 19.354 1.00 17.37 ? 426 SER A OG 1 ATOM 2881 N N . ASN A 1 375 ? 29.259 144.244 21.353 1.00 16.66 ? 427 ASN A N 1 ATOM 2882 C CA . ASN A 1 375 ? 28.346 143.998 22.468 1.00 19.34 ? 427 ASN A CA 1 ATOM 2883 C C . ASN A 1 375 ? 26.975 144.654 22.295 1.00 18.19 ? 427 ASN A C 1 ATOM 2884 O O . ASN A 1 375 ? 26.422 145.223 23.231 1.00 20.49 ? 427 ASN A O 1 ATOM 2885 C CB . ASN A 1 375 ? 28.968 144.474 23.781 1.00 22.25 ? 427 ASN A CB 1 ATOM 2886 C CG . ASN A 1 375 ? 28.219 143.957 24.998 1.00 29.53 ? 427 ASN A CG 1 ATOM 2887 O OD1 . ASN A 1 375 ? 27.650 142.868 24.972 1.00 33.56 ? 427 ASN A OD1 1 ATOM 2888 N ND2 . ASN A 1 375 ? 28.197 144.748 26.062 1.00 35.82 ? 427 ASN A ND2 1 ATOM 2889 N N . ALA A 1 376 ? 26.432 144.561 21.089 1.00 15.43 ? 428 ALA A N 1 ATOM 2890 C CA . ALA A 1 376 ? 25.121 145.111 20.779 1.00 12.95 ? 428 ALA A CA 1 ATOM 2891 C C . ALA A 1 376 ? 24.100 143.991 20.695 1.00 13.32 ? 428 ALA A C 1 ATOM 2892 O O . ALA A 1 376 ? 24.470 142.833 20.515 1.00 15.95 ? 428 ALA A O 1 ATOM 2893 C CB . ALA A 1 376 ? 25.163 145.874 19.468 1.00 17.36 ? 428 ALA A CB 1 ATOM 2894 N N . THR A 1 377 ? 22.828 144.342 20.836 1.00 13.75 ? 429 THR A N 1 ATOM 2895 C CA . THR A 1 377 ? 21.753 143.414 20.508 1.00 13.32 ? 429 THR A CA 1 ATOM 2896 C C . THR A 1 377 ? 21.446 143.523 19.019 1.00 14.22 ? 429 THR A C 1 ATOM 2897 O O . THR A 1 377 ? 21.867 144.471 18.355 1.00 14.38 ? 429 THR A O 1 ATOM 2898 C CB . THR A 1 377 ? 20.466 143.698 21.290 1.00 16.42 ? 429 THR A CB 1 ATOM 2899 O OG1 . THR A 1 377 ? 19.962 144.985 20.916 1.00 17.24 ? 429 THR A OG1 1 ATOM 2900 C CG2 . THR A 1 377 ? 20.699 143.655 22.807 1.00 19.45 ? 429 THR A CG2 1 ATOM 2901 N N . ALA A 1 378 ? 20.688 142.569 18.491 1.00 13.41 ? 430 ALA A N 1 ATOM 2902 C CA . ALA A 1 378 ? 20.341 142.609 17.078 1.00 11.87 ? 430 ALA A CA 1 ATOM 2903 C C . ALA A 1 378 ? 19.447 143.814 16.783 1.00 12.18 ? 430 ALA A C 1 ATOM 2904 O O . ALA A 1 378 ? 19.595 144.469 15.755 1.00 12.94 ? 430 ALA A O 1 ATOM 2905 C CB . ALA A 1 378 ? 19.655 141.324 16.663 1.00 15.29 ? 430 ALA A CB 1 ATOM 2906 N N . GLU A 1 379 ? 18.518 144.102 17.684 1.00 11.91 ? 431 GLU A N 1 ATOM 2907 C CA . GLU A 1 379 ? 17.666 145.280 17.536 1.00 11.34 ? 431 GLU A CA 1 ATOM 2908 C C . GLU A 1 379 ? 18.509 146.556 17.476 1.00 14.67 ? 431 GLU A C 1 ATOM 2909 O O . GLU A 1 379 ? 18.265 147.424 16.635 1.00 14.08 ? 431 GLU A O 1 ATOM 2910 C CB . GLU A 1 379 ? 16.659 145.368 18.681 1.00 13.19 ? 431 GLU A CB 1 ATOM 2911 C CG . GLU A 1 379 ? 15.741 146.579 18.595 1.00 16.59 ? 431 GLU A CG 1 ATOM 2912 C CD . GLU A 1 379 ? 14.752 146.636 19.742 1.00 22.24 ? 431 GLU A CD 1 ATOM 2913 O OE1 . GLU A 1 379 ? 14.820 145.760 20.633 1.00 30.55 ? 431 GLU A OE1 1 ATOM 2914 O OE2 . GLU A 1 379 ? 13.903 147.549 19.758 1.00 18.06 ? 431 GLU A OE2 1 ATOM 2915 N N . GLN A 1 380 ? 19.487 146.675 18.371 1.00 13.48 ? 432 GLN A N 1 ATOM 2916 C CA . GLN A 1 380 ? 20.401 147.824 18.354 1.00 13.48 ? 432 GLN A CA 1 ATOM 2917 C C . GLN A 1 380 ? 21.161 147.935 17.037 1.00 14.29 ? 432 GLN A C 1 ATOM 2918 O O . GLN A 1 380 ? 21.391 149.036 16.536 1.00 14.10 ? 432 GLN A O 1 ATOM 2919 C CB . GLN A 1 380 ? 21.391 147.743 19.517 1.00 15.57 ? 432 GLN A CB 1 ATOM 2920 C CG . GLN A 1 380 ? 20.761 148.060 20.858 1.00 19.91 ? 432 GLN A CG 1 ATOM 2921 C CD . GLN A 1 380 ? 21.736 147.910 22.005 1.00 24.27 ? 432 GLN A CD 1 ATOM 2922 O OE1 . GLN A 1 380 ? 22.710 147.167 21.911 1.00 19.63 ? 432 GLN A OE1 1 ATOM 2923 N NE2 . GLN A 1 380 ? 21.487 148.628 23.090 1.00 34.68 ? 432 GLN A NE2 1 ATOM 2924 N N . CYS A 1 381 ? 21.572 146.800 16.483 1.00 13.47 ? 433 CYS A N 1 ATOM 2925 C CA . CYS A 1 381 ? 22.226 146.770 15.184 1.00 13.31 ? 433 CYS A CA 1 ATOM 2926 C C . CYS A 1 381 ? 21.350 147.397 14.106 1.00 13.12 ? 433 CYS A C 1 ATOM 2927 O O . CYS A 1 381 ? 21.795 148.259 13.349 1.00 12.41 ? 433 CYS A O 1 ATOM 2928 C CB . CYS A 1 381 ? 22.561 145.327 14.814 1.00 15.48 ? 433 CYS A CB 1 ATOM 2929 S SG . CYS A 1 381 ? 23.518 145.113 13.328 1.00 19.19 ? 433 CYS A SG 1 ATOM 2930 N N . GLY A 1 382 ? 20.092 146.975 14.042 1.00 12.41 ? 434 GLY A N 1 ATOM 2931 C CA . GLY A 1 382 ? 19.182 147.525 13.061 1.00 12.18 ? 434 GLY A CA 1 ATOM 2932 C C . GLY A 1 382 ? 18.889 148.999 13.297 1.00 11.91 ? 434 GLY A C 1 ATOM 2933 O O . GLY A 1 382 ? 18.780 149.777 12.348 1.00 12.45 ? 434 GLY A O 1 ATOM 2934 N N . GLN A 1 383 ? 18.740 149.383 14.561 1.00 12.10 ? 435 GLN A N 1 ATOM 2935 C CA . GLN A 1 383 ? 18.482 150.778 14.911 1.00 11.49 ? 435 GLN A CA 1 ATOM 2936 C C . GLN A 1 383 ? 19.644 151.677 14.519 1.00 12.26 ? 435 GLN A C 1 ATOM 2937 O O . GLN A 1 383 ? 19.454 152.720 13.889 1.00 13.66 ? 435 GLN A O 1 ATOM 2938 C CB . GLN A 1 383 ? 18.226 150.920 16.412 1.00 12.98 ? 435 GLN A CB 1 ATOM 2939 C CG . GLN A 1 383 ? 16.911 150.329 16.877 1.00 14.38 ? 435 GLN A CG 1 ATOM 2940 C CD . GLN A 1 383 ? 16.789 150.308 18.387 1.00 18.47 ? 435 GLN A CD 1 ATOM 2941 O OE1 . GLN A 1 383 ? 17.746 150.001 19.096 1.00 21.24 ? 435 GLN A OE1 1 ATOM 2942 N NE2 . GLN A 1 383 ? 15.614 150.648 18.887 1.00 15.25 ? 435 GLN A NE2 1 ATOM 2943 N N . ARG A 1 384 ? 20.851 151.288 14.904 1.00 12.61 ? 436 ARG A N 1 ATOM 2944 C CA . ARG A 1 384 ? 22.002 152.123 14.582 1.00 12.44 ? 436 ARG A CA 1 ATOM 2945 C C . ARG A 1 384 ? 22.263 152.149 13.079 1.00 12.14 ? 436 ARG A C 1 ATOM 2946 O O . ARG A 1 384 ? 22.656 153.178 12.546 1.00 12.24 ? 436 ARG A O 1 ATOM 2947 C CB . ARG A 1 384 ? 23.255 151.667 15.333 1.00 14.01 ? 436 ARG A CB 1 ATOM 2948 C CG . ARG A 1 384 ? 23.280 152.061 16.816 1.00 19.03 ? 436 ARG A CG 1 ATOM 2949 C CD . ARG A 1 384 ? 23.052 153.578 17.089 1.00 18.34 ? 436 ARG A CD 1 ATOM 2950 N NE . ARG A 1 384 ? 24.161 154.442 16.677 1.00 18.66 ? 436 ARG A NE 1 ATOM 2951 C CZ . ARG A 1 384 ? 24.172 155.766 16.821 1.00 15.86 ? 436 ARG A CZ 1 ATOM 2952 N NH1 . ARG A 1 384 ? 25.222 156.480 16.442 1.00 16.78 ? 436 ARG A NH1 1 ATOM 2953 N NH2 . ARG A 1 384 ? 23.127 156.388 17.346 1.00 16.78 ? 436 ARG A NH2 1 ATOM 2954 N N . LEU A 1 385 ? 22.049 151.035 12.383 1.00 10.26 ? 437 LEU A N 1 ATOM 2955 C CA . LEU A 1 385 ? 22.157 151.053 10.927 1.00 10.69 ? 437 LEU A CA 1 ATOM 2956 C C . LEU A 1 385 ? 21.265 152.150 10.320 1.00 10.56 ? 437 LEU A C 1 ATOM 2957 O O . LEU A 1 385 ? 21.708 152.950 9.503 1.00 10.69 ? 437 LEU A O 1 ATOM 2958 C CB . LEU A 1 385 ? 21.782 149.688 10.343 1.00 10.43 ? 437 LEU A CB 1 ATOM 2959 C CG . LEU A 1 385 ? 21.742 149.616 8.815 1.00 9.78 ? 437 LEU A CG 1 ATOM 2960 C CD1 . LEU A 1 385 ? 23.112 149.915 8.212 1.00 11.80 ? 437 LEU A CD1 1 ATOM 2961 C CD2 . LEU A 1 385 ? 21.247 148.248 8.371 1.00 12.11 ? 437 LEU A CD2 1 ATOM 2962 N N . PHE A 1 386 ? 20.008 152.181 10.746 1.00 11.78 ? 438 PHE A N 1 ATOM 2963 C CA . PHE A 1 386 ? 19.048 153.191 10.311 1.00 9.85 ? 438 PHE A CA 1 ATOM 2964 C C . PHE A 1 386 ? 19.564 154.606 10.588 1.00 9.63 ? 438 PHE A C 1 ATOM 2965 O O . PHE A 1 386 ? 19.523 155.478 9.711 1.00 11.16 ? 438 PHE A O 1 ATOM 2966 C CB . PHE A 1 386 ? 17.712 152.925 11.027 1.00 10.45 ? 438 PHE A CB 1 ATOM 2967 C CG . PHE A 1 386 ? 16.614 153.916 10.739 1.00 9.16 ? 438 PHE A CG 1 ATOM 2968 C CD1 . PHE A 1 386 ? 16.244 154.236 9.443 1.00 9.20 ? 438 PHE A CD1 1 ATOM 2969 C CD2 . PHE A 1 386 ? 15.903 154.479 11.791 1.00 10.83 ? 438 PHE A CD2 1 ATOM 2970 C CE1 . PHE A 1 386 ? 15.210 155.115 9.208 1.00 10.93 ? 438 PHE A CE1 1 ATOM 2971 C CE2 . PHE A 1 386 ? 14.867 155.362 11.559 1.00 9.06 ? 438 PHE A CE2 1 ATOM 2972 C CZ . PHE A 1 386 ? 14.524 155.685 10.266 1.00 10.82 ? 438 PHE A CZ 1 ATOM 2973 N N . MET A 1 387 ? 20.063 154.815 11.805 1.00 10.88 ? 439 MET A N 1 ATOM 2974 C CA . MET A 1 387 ? 20.534 156.132 12.234 1.00 10.40 ? 439 MET A CA 1 ATOM 2975 C C . MET A 1 387 ? 21.853 156.540 11.574 1.00 11.87 ? 439 MET A C 1 ATOM 2976 O O . MET A 1 387 ? 22.200 157.714 11.600 1.00 12.19 ? 439 MET A O 1 ATOM 2977 C CB . MET A 1 387 ? 20.691 156.158 13.755 1.00 13.23 ? 439 MET A CB 1 ATOM 2978 C CG . MET A 1 387 ? 19.397 155.905 14.514 1.00 15.45 ? 439 MET A CG 1 ATOM 2979 S SD . MET A 1 387 ? 19.633 155.534 16.271 1.00 18.36 ? 439 MET A SD 1 ATOM 2980 C CE . MET A 1 387 ? 19.851 157.185 16.907 1.00 16.78 ? 439 MET A CE 1 ATOM 2981 N N . LEU A 1 388 ? 22.569 155.580 10.990 1.00 10.99 ? 440 LEU A N 1 ATOM 2982 C CA . LEU A 1 388 ? 23.859 155.823 10.342 1.00 11.64 ? 440 LEU A CA 1 ATOM 2983 C C . LEU A 1 388 ? 23.774 155.681 8.819 1.00 10.99 ? 440 LEU A C 1 ATOM 2984 O O . LEU A 1 388 ? 24.794 155.573 8.138 1.00 10.90 ? 440 LEU A O 1 ATOM 2985 C CB . LEU A 1 388 ? 24.911 154.847 10.890 1.00 11.59 ? 440 LEU A CB 1 ATOM 2986 C CG . LEU A 1 388 ? 25.271 154.929 12.371 1.00 12.66 ? 440 LEU A CG 1 ATOM 2987 C CD1 . LEU A 1 388 ? 26.228 153.806 12.742 1.00 12.62 ? 440 LEU A CD1 1 ATOM 2988 C CD2 . LEU A 1 388 ? 25.881 156.289 12.689 1.00 14.56 ? 440 LEU A CD2 1 ATOM 2989 N N . SER A 1 389 ? 22.563 155.698 8.273 1.00 12.23 ? 441 SER A N 1 ATOM 2990 C CA . SER A 1 389 ? 22.392 155.386 6.858 1.00 9.91 ? 441 SER A CA 1 ATOM 2991 C C . SER A 1 389 ? 22.564 156.626 5.982 1.00 10.27 ? 441 SER A C 1 ATOM 2992 O O . SER A 1 389 ? 23.670 156.889 5.500 1.00 11.56 ? 441 SER A O 1 ATOM 2993 C CB . SER A 1 389 ? 21.025 154.702 6.624 1.00 10.64 ? 441 SER A CB 1 ATOM 2994 O OG . SER A 1 389 ? 19.925 155.520 7.000 1.00 11.46 ? 441 SER A OG 1 ATOM 2995 N N . SER A 1 390 ? 21.496 157.378 5.759 1.00 9.78 ? 442 SER A N 1 ATOM 2996 C CA . SER A 1 390 ? 21.585 158.570 4.932 1.00 10.65 ? 442 SER A CA 1 ATOM 2997 C C . SER A 1 390 ? 20.497 159.528 5.342 1.00 9.59 ? 442 SER A C 1 ATOM 2998 O O . SER A 1 390 ? 19.476 159.126 5.902 1.00 10.50 ? 442 SER A O 1 ATOM 2999 C CB . SER A 1 390 ? 21.485 158.228 3.444 1.00 11.69 ? 442 SER A CB 1 ATOM 3000 O OG . SER A 1 390 ? 20.297 157.509 3.155 1.00 12.29 ? 442 SER A OG 1 ATOM 3001 N N . ALA A 1 391 ? 20.729 160.809 5.101 1.00 11.26 ? 443 ALA A N 1 ATOM 3002 C CA . ALA A 1 391 ? 19.786 161.826 5.514 1.00 10.83 ? 443 ALA A CA 1 ATOM 3003 C C . ALA A 1 391 ? 19.929 163.063 4.658 1.00 13.64 ? 443 ALA A C 1 ATOM 3004 O O . ALA A 1 391 ? 21.040 163.506 4.359 1.00 14.50 ? 443 ALA A O 1 ATOM 3005 C CB . ALA A 1 391 ? 19.983 162.179 6.964 1.00 12.06 ? 443 ALA A CB 1 ATOM 3006 N N . ASP A 1 392 ? 18.793 163.606 4.255 1.00 10.46 ? 444 ASP A N 1 ATOM 3007 C CA . ASP A 1 392 ? 18.755 164.886 3.568 1.00 10.59 ? 444 ASP A CA 1 ATOM 3008 C C . ASP A 1 392 ? 18.588 165.987 4.626 1.00 11.54 ? 444 ASP A C 1 ATOM 3009 O O . ASP A 1 392 ? 18.424 165.701 5.806 1.00 13.88 ? 444 ASP A O 1 ATOM 3010 C CB . ASP A 1 392 ? 17.631 164.878 2.523 1.00 11.60 ? 444 ASP A CB 1 ATOM 3011 C CG . ASP A 1 392 ? 17.843 163.802 1.468 1.00 13.43 ? 444 ASP A CG 1 ATOM 3012 O OD1 . ASP A 1 392 ? 18.994 163.671 0.993 1.00 16.52 ? 444 ASP A OD1 1 ATOM 3013 O OD2 . ASP A 1 392 ? 16.886 163.072 1.123 1.00 13.02 ? 444 ASP A OD2 1 ATOM 3014 N N . GLY A 1 393 ? 18.672 167.244 4.207 1.00 11.95 ? 445 GLY A N 1 ATOM 3015 C CA . GLY A 1 393 ? 18.551 168.366 5.128 1.00 12.52 ? 445 GLY A CA 1 ATOM 3016 C C . GLY A 1 393 ? 19.846 168.837 5.776 1.00 14.12 ? 445 GLY A C 1 ATOM 3017 O O . GLY A 1 393 ? 19.799 169.653 6.698 1.00 15.32 ? 445 GLY A O 1 ATOM 3018 N N . SER A 1 394 ? 20.976 168.302 5.313 1.00 11.82 ? 446 SER A N 1 ATOM 3019 C CA . SER A 1 394 ? 22.329 168.783 5.660 1.00 14.33 ? 446 SER A CA 1 ATOM 3020 C C . SER A 1 394 ? 22.814 168.505 7.080 1.00 11.35 ? 446 SER A C 1 ATOM 3021 O O . SER A 1 394 ? 23.897 167.946 7.263 1.00 13.32 ? 446 SER A O 1 ATOM 3022 C CB . SER A 1 394 ? 22.437 170.290 5.411 1.00 14.65 ? 446 SER A CB 1 ATOM 3023 O OG . SER A 1 394 ? 22.308 170.580 4.031 1.00 19.75 ? 446 SER A OG 1 ATOM 3024 N N . SER A 1 395 ? 22.039 168.875 8.090 1.00 13.30 ? 447 SER A N 1 ATOM 3025 C CA . SER A 1 395 ? 22.595 168.963 9.430 1.00 13.05 ? 447 SER A CA 1 ATOM 3026 C C . SER A 1 395 ? 23.025 167.627 10.043 1.00 13.13 ? 447 SER A C 1 ATOM 3027 O O . SER A 1 395 ? 23.901 167.609 10.905 1.00 13.37 ? 447 SER A O 1 ATOM 3028 C CB . SER A 1 395 ? 21.601 169.659 10.353 1.00 16.74 ? 447 SER A CB 1 ATOM 3029 O OG . SER A 1 395 ? 20.394 168.946 10.437 1.00 25.59 ? 447 SER A OG 1 ATOM 3030 N N . LEU A 1 396 ? 22.440 166.513 9.599 1.00 12.20 ? 448 LEU A N 1 ATOM 3031 C CA . LEU A 1 396 ? 22.804 165.192 10.125 1.00 12.31 ? 448 LEU A CA 1 ATOM 3032 C C . LEU A 1 396 ? 23.943 164.495 9.361 1.00 14.12 ? 448 LEU A C 1 ATOM 3033 O O . LEU A 1 396 ? 24.278 163.341 9.648 1.00 13.36 ? 448 LEU A O 1 ATOM 3034 C CB . LEU A 1 396 ? 21.568 164.288 10.128 1.00 13.22 ? 448 LEU A CB 1 ATOM 3035 C CG . LEU A 1 396 ? 20.502 164.658 11.152 1.00 14.25 ? 448 LEU A CG 1 ATOM 3036 C CD1 . LEU A 1 396 ? 19.213 163.881 10.943 1.00 18.80 ? 448 LEU A CD1 1 ATOM 3037 C CD2 . LEU A 1 396 ? 20.997 164.452 12.560 1.00 16.49 ? 448 LEU A CD2 1 ATOM 3038 N N . SER A 1 397 ? 24.556 165.192 8.407 1.00 11.95 ? 449 SER A N 1 ATOM 3039 C CA . SER A 1 397 ? 25.591 164.580 7.570 1.00 12.48 ? 449 SER A CA 1 ATOM 3040 C C . SER A 1 397 ? 26.797 164.051 8.357 1.00 15.27 ? 449 SER A C 1 ATOM 3041 O O . SER A 1 397 ? 27.478 163.116 7.917 1.00 15.54 ? 449 SER A O 1 ATOM 3042 C CB . SER A 1 397 ? 26.066 165.583 6.514 1.00 14.84 ? 449 SER A CB 1 ATOM 3043 O OG . SER A 1 397 ? 26.797 166.631 7.127 1.00 15.50 ? 449 SER A OG 1 ATOM 3044 N N . SER A 1 398 ? 27.070 164.634 9.518 1.00 11.60 ? 450 SER A N 1 ATOM 3045 C CA . SER A 1 398 ? 28.205 164.225 10.340 1.00 12.72 ? 450 SER A CA 1 ATOM 3046 C C . SER A 1 398 ? 27.899 162.926 11.084 1.00 13.46 ? 450 SER A C 1 ATOM 3047 O O . SER A 1 398 ? 28.809 162.248 11.568 1.00 14.90 ? 450 SER A O 1 ATOM 3048 C CB . SER A 1 398 ? 28.567 165.338 11.329 1.00 13.16 ? 450 SER A CB 1 ATOM 3049 O OG . SER A 1 398 ? 27.446 165.688 12.119 1.00 13.69 ? 450 SER A OG 1 ATOM 3050 N N . GLN A 1 399 ? 26.613 162.590 11.160 1.00 12.47 ? 451 GLN A N 1 ATOM 3051 C CA . GLN A 1 399 ? 26.172 161.373 11.837 1.00 12.46 ? 451 GLN A CA 1 ATOM 3052 C C . GLN A 1 399 ? 25.991 160.216 10.860 1.00 12.05 ? 451 GLN A C 1 ATOM 3053 O O . GLN A 1 399 ? 26.529 159.136 11.083 1.00 11.91 ? 451 GLN A O 1 ATOM 3054 C CB . GLN A 1 399 ? 24.865 161.620 12.589 1.00 11.44 ? 451 GLN A CB 1 ATOM 3055 C CG . GLN A 1 399 ? 24.265 160.374 13.216 1.00 13.54 ? 451 GLN A CG 1 ATOM 3056 C CD . GLN A 1 399 ? 23.078 160.702 14.089 1.00 16.30 ? 451 GLN A CD 1 ATOM 3057 O OE1 . GLN A 1 399 ? 23.147 161.593 14.943 1.00 15.12 ? 451 GLN A OE1 1 ATOM 3058 N NE2 . GLN A 1 399 ? 21.968 159.991 13.876 1.00 14.41 ? 451 GLN A NE2 1 ATOM 3059 N N . VAL A 1 400 ? 25.208 160.423 9.806 1.00 11.15 ? 452 VAL A N 1 ATOM 3060 C CA . VAL A 1 400 ? 25.011 159.350 8.841 1.00 10.73 ? 452 VAL A CA 1 ATOM 3061 C C . VAL A 1 400 ? 26.303 159.100 8.070 1.00 12.18 ? 452 VAL A C 1 ATOM 3062 O O . VAL A 1 400 ? 27.109 160.010 7.870 1.00 11.91 ? 452 VAL A O 1 ATOM 3063 C CB . VAL A 1 400 ? 23.844 159.644 7.868 1.00 11.08 ? 452 VAL A CB 1 ATOM 3064 C CG1 . VAL A 1 400 ? 22.538 159.765 8.637 1.00 13.02 ? 452 VAL A CG1 1 ATOM 3065 C CG2 . VAL A 1 400 ? 24.098 160.895 7.043 1.00 12.58 ? 452 VAL A CG2 1 ATOM 3066 N N . ARG A 1 401 ? 26.494 157.851 7.649 1.00 10.65 ? 453 ARG A N 1 ATOM 3067 C CA . ARG A 1 401 ? 27.767 157.382 7.106 1.00 11.37 ? 453 ARG A CA 1 ATOM 3068 C C . ARG A 1 401 ? 27.648 156.708 5.746 1.00 11.88 ? 453 ARG A C 1 ATOM 3069 O O . ARG A 1 401 ? 28.658 156.352 5.142 1.00 13.56 ? 453 ARG A O 1 ATOM 3070 C CB . ARG A 1 401 ? 28.405 156.380 8.065 1.00 10.60 ? 453 ARG A CB 1 ATOM 3071 C CG . ARG A 1 401 ? 28.704 156.879 9.480 1.00 12.73 ? 453 ARG A CG 1 ATOM 3072 C CD . ARG A 1 401 ? 29.940 157.763 9.526 1.00 17.43 ? 453 ARG A CD 1 ATOM 3073 N NE . ARG A 1 401 ? 29.620 159.128 9.146 1.00 16.19 ? 453 ARG A NE 1 ATOM 3074 C CZ . ARG A 1 401 ? 30.518 160.077 8.908 1.00 16.44 ? 453 ARG A CZ 1 ATOM 3075 N NH1 . ARG A 1 401 ? 30.107 161.290 8.570 1.00 19.15 ? 453 ARG A NH1 1 ATOM 3076 N NH2 . ARG A 1 401 ? 31.815 159.817 9.010 1.00 15.97 ? 453 ARG A NH2 1 ATOM 3077 N N . GLY A 1 402 ? 26.420 156.483 5.290 1.00 11.96 ? 454 GLY A N 1 ATOM 3078 C CA . GLY A 1 402 ? 26.197 155.781 4.038 1.00 12.70 ? 454 GLY A CA 1 ATOM 3079 C C . GLY A 1 402 ? 26.039 154.281 4.203 1.00 12.96 ? 454 GLY A C 1 ATOM 3080 O O . GLY A 1 402 ? 26.161 153.540 3.224 1.00 12.27 ? 454 GLY A O 1 ATOM 3081 N N . TYR A 1 403 ? 25.774 153.829 5.425 1.00 11.60 ? 455 TYR A N 1 ATOM 3082 C CA . TYR A 1 403 ? 25.607 152.399 5.697 1.00 10.42 ? 455 TYR A CA 1 ATOM 3083 C C . TYR A 1 403 ? 24.157 151.990 5.457 1.00 10.85 ? 455 TYR A C 1 ATOM 3084 O O . TYR A 1 403 ? 23.259 152.530 6.100 1.00 11.77 ? 455 TYR A O 1 ATOM 3085 C CB . TYR A 1 403 ? 25.971 152.051 7.146 1.00 11.74 ? 455 TYR A CB 1 ATOM 3086 C CG . TYR A 1 403 ? 27.316 152.532 7.657 1.00 11.73 ? 455 TYR A CG 1 ATOM 3087 C CD1 . TYR A 1 403 ? 28.385 152.759 6.799 1.00 14.30 ? 455 TYR A CD1 1 ATOM 3088 C CD2 . TYR A 1 403 ? 27.504 152.740 9.015 1.00 12.30 ? 455 TYR A CD2 1 ATOM 3089 C CE1 . TYR A 1 403 ? 29.613 153.201 7.296 1.00 13.27 ? 455 TYR A CE1 1 ATOM 3090 C CE2 . TYR A 1 403 ? 28.715 153.161 9.514 1.00 13.35 ? 455 TYR A CE2 1 ATOM 3091 C CZ . TYR A 1 403 ? 29.756 153.390 8.658 1.00 11.71 ? 455 TYR A CZ 1 ATOM 3092 O OH . TYR A 1 403 ? 30.946 153.837 9.205 1.00 15.25 ? 455 TYR A OH 1 ATOM 3093 N N . HIS A 1 404 ? 23.926 151.025 4.569 1.00 10.98 ? 456 HIS A N 1 ATOM 3094 C CA . HIS A 1 404 ? 22.558 150.556 4.313 1.00 10.91 ? 456 HIS A CA 1 ATOM 3095 C C . HIS A 1 404 ? 22.359 149.078 4.577 1.00 9.50 ? 456 HIS A C 1 ATOM 3096 O O . HIS A 1 404 ? 21.231 148.590 4.476 1.00 10.88 ? 456 HIS A O 1 ATOM 3097 C CB . HIS A 1 404 ? 22.149 150.871 2.881 1.00 9.20 ? 456 HIS A CB 1 ATOM 3098 C CG . HIS A 1 404 ? 22.034 152.336 2.636 1.00 10.05 ? 456 HIS A CG 1 ATOM 3099 N ND1 . HIS A 1 404 ? 21.066 153.109 3.241 1.00 11.75 ? 456 HIS A ND1 1 ATOM 3100 C CD2 . HIS A 1 404 ? 22.817 153.186 1.934 1.00 11.21 ? 456 HIS A CD2 1 ATOM 3101 C CE1 . HIS A 1 404 ? 21.233 154.371 2.885 1.00 10.89 ? 456 HIS A CE1 1 ATOM 3102 N NE2 . HIS A 1 404 ? 22.292 154.445 2.097 1.00 11.52 ? 456 HIS A NE2 1 ATOM 3103 N N . TRP A 1 405 ? 23.435 148.383 4.930 1.00 10.32 ? 457 TRP A N 1 ATOM 3104 C CA . TRP A 1 405 ? 23.414 146.947 5.183 1.00 10.57 ? 457 TRP A CA 1 ATOM 3105 C C . TRP A 1 405 ? 24.256 146.679 6.408 1.00 12.40 ? 457 TRP A C 1 ATOM 3106 O O . TRP A 1 405 ? 25.343 147.248 6.543 1.00 11.82 ? 457 TRP A O 1 ATOM 3107 C CB . TRP A 1 405 ? 23.964 146.166 3.980 1.00 10.12 ? 457 TRP A CB 1 ATOM 3108 C CG . TRP A 1 405 ? 23.355 146.589 2.685 1.00 11.76 ? 457 TRP A CG 1 ATOM 3109 C CD1 . TRP A 1 405 ? 22.245 146.062 2.084 1.00 10.95 ? 457 TRP A CD1 1 ATOM 3110 C CD2 . TRP A 1 405 ? 23.795 147.661 1.839 1.00 10.98 ? 457 TRP A CD2 1 ATOM 3111 N NE1 . TRP A 1 405 ? 21.974 146.734 0.914 1.00 12.39 ? 457 TRP A NE1 1 ATOM 3112 C CE2 . TRP A 1 405 ? 22.909 147.723 0.744 1.00 12.99 ? 457 TRP A CE2 1 ATOM 3113 C CE3 . TRP A 1 405 ? 24.853 148.576 1.901 1.00 9.55 ? 457 TRP A CE3 1 ATOM 3114 C CZ2 . TRP A 1 405 ? 23.057 148.648 -0.283 1.00 11.25 ? 457 TRP A CZ2 1 ATOM 3115 C CZ3 . TRP A 1 405 ? 24.992 149.492 0.887 1.00 12.24 ? 457 TRP A CZ3 1 ATOM 3116 C CH2 . TRP A 1 405 ? 24.100 149.536 -0.187 1.00 11.86 ? 457 TRP A CH2 1 ATOM 3117 N N . ALA A 1 406 ? 23.757 145.820 7.295 1.00 10.80 ? 458 ALA A N 1 ATOM 3118 C CA . ALA A 1 406 ? 24.534 145.358 8.430 1.00 11.91 ? 458 ALA A CA 1 ATOM 3119 C C . ALA A 1 406 ? 24.361 143.864 8.623 1.00 12.33 ? 458 ALA A C 1 ATOM 3120 O O . ALA A 1 406 ? 23.283 143.314 8.367 1.00 10.75 ? 458 ALA A O 1 ATOM 3121 C CB . ALA A 1 406 ? 24.135 146.089 9.695 1.00 12.16 ? 458 ALA A CB 1 ATOM 3122 N N . THR A 1 407 ? 25.421 143.216 9.090 1.00 11.40 ? 459 THR A N 1 ATOM 3123 C CA . THR A 1 407 ? 25.378 141.816 9.495 1.00 9.83 ? 459 THR A CA 1 ATOM 3124 C C . THR A 1 407 ? 25.619 141.776 10.977 1.00 11.87 ? 459 THR A C 1 ATOM 3125 O O . THR A 1 407 ? 26.646 142.277 11.454 1.00 13.38 ? 459 THR A O 1 ATOM 3126 C CB . THR A 1 407 ? 26.447 140.957 8.781 1.00 10.95 ? 459 THR A CB 1 ATOM 3127 O OG1 . THR A 1 407 ? 26.191 140.922 7.373 1.00 12.87 ? 459 THR A OG1 1 ATOM 3128 C CG2 . THR A 1 407 ? 26.482 139.522 9.332 1.00 13.80 ? 459 THR A CG2 1 ATOM 3129 N N . PHE A 1 408 ? 24.667 141.200 11.699 1.00 11.05 ? 460 PHE A N 1 ATOM 3130 C CA . PHE A 1 408 ? 24.804 140.962 13.122 1.00 11.85 ? 460 PHE A CA 1 ATOM 3131 C C . PHE A 1 408 ? 25.323 139.555 13.344 1.00 13.85 ? 460 PHE A C 1 ATOM 3132 O O . PHE A 1 408 ? 24.788 138.604 12.784 1.00 14.14 ? 460 PHE A O 1 ATOM 3133 C CB . PHE A 1 408 ? 23.474 141.154 13.835 1.00 12.83 ? 460 PHE A CB 1 ATOM 3134 C CG . PHE A 1 408 ? 23.531 140.872 15.305 1.00 14.44 ? 460 PHE A CG 1 ATOM 3135 C CD1 . PHE A 1 408 ? 24.044 141.813 16.177 1.00 17.57 ? 460 PHE A CD1 1 ATOM 3136 C CD2 . PHE A 1 408 ? 23.051 139.677 15.819 1.00 14.48 ? 460 PHE A CD2 1 ATOM 3137 C CE1 . PHE A 1 408 ? 24.098 141.569 17.534 1.00 15.87 ? 460 PHE A CE1 1 ATOM 3138 C CE2 . PHE A 1 408 ? 23.095 139.427 17.181 1.00 16.40 ? 460 PHE A CE2 1 ATOM 3139 C CZ . PHE A 1 408 ? 23.616 140.373 18.040 1.00 14.85 ? 460 PHE A CZ 1 ATOM 3140 N N . VAL A 1 409 ? 26.384 139.432 14.135 1.00 12.46 ? 461 VAL A N 1 ATOM 3141 C CA . VAL A 1 409 ? 26.959 138.137 14.469 1.00 12.84 ? 461 VAL A CA 1 ATOM 3142 C C . VAL A 1 409 ? 26.837 137.934 15.970 1.00 15.05 ? 461 VAL A C 1 ATOM 3143 O O . VAL A 1 409 ? 27.530 138.585 16.753 1.00 15.06 ? 461 VAL A O 1 ATOM 3144 C CB . VAL A 1 409 ? 28.434 138.044 14.027 1.00 15.25 ? 461 VAL A CB 1 ATOM 3145 C CG1 . VAL A 1 409 ? 29.001 136.645 14.324 1.00 16.95 ? 461 VAL A CG1 1 ATOM 3146 C CG2 . VAL A 1 409 ? 28.573 138.385 12.544 1.00 15.60 ? 461 VAL A CG2 1 ATOM 3147 N N . ALA A 1 410 ? 25.946 137.032 16.377 1.00 15.19 ? 462 ALA A N 1 ATOM 3148 C CA . ALA A 1 410 ? 25.731 136.747 17.789 1.00 15.45 ? 462 ALA A CA 1 ATOM 3149 C C . ALA A 1 410 ? 26.923 136.004 18.356 1.00 17.02 ? 462 ALA A C 1 ATOM 3150 O O . ALA A 1 410 ? 27.543 135.186 17.671 1.00 20.56 ? 462 ALA A O 1 ATOM 3151 C CB . ALA A 1 410 ? 24.470 135.933 17.988 1.00 18.10 ? 462 ALA A CB 1 ATOM 3152 N N . THR A 1 411 ? 27.240 136.290 19.611 1.00 20.57 ? 463 THR A N 1 ATOM 3153 C CA . THR A 1 411 ? 28.352 135.623 20.270 1.00 26.63 ? 463 THR A CA 1 ATOM 3154 C C . THR A 1 411 ? 28.126 134.110 20.304 1.00 32.55 ? 463 THR A C 1 ATOM 3155 O O . THR A 1 411 ? 29.007 133.345 19.909 1.00 30.69 ? 463 THR A O 1 ATOM 3156 C CB . THR A 1 411 ? 28.554 136.168 21.691 1.00 29.70 ? 463 THR A CB 1 ATOM 3157 O OG1 . THR A 1 411 ? 28.844 137.572 21.616 1.00 27.43 ? 463 THR A OG1 1 ATOM 3158 C CG2 . THR A 1 411 ? 29.708 135.455 22.391 1.00 34.30 ? 463 THR A CG2 1 ATOM 3159 N N . ASP A 1 412 ? 26.947 133.681 20.755 1.00 25.89 ? 464 ASP A N 1 ATOM 3160 C CA . ASP A 1 412 ? 26.624 132.253 20.798 1.00 28.41 ? 464 ASP A CA 1 ATOM 3161 C C . ASP A 1 412 ? 25.118 131.988 20.845 1.00 34.27 ? 464 ASP A C 1 ATOM 3162 O O . ASP A 1 412 ? 24.622 131.283 21.726 1.00 41.39 ? 464 ASP A O 1 ATOM 3163 C CB . ASP A 1 412 ? 27.305 131.589 22.000 1.00 40.95 ? 464 ASP A CB 1 ATOM 3164 C CG . ASP A 1 412 ? 26.964 132.262 23.317 1.00 45.16 ? 464 ASP A CG 1 ATOM 3165 O OD1 . ASP A 1 412 ? 25.932 132.965 23.395 1.00 47.61 ? 464 ASP A OD1 1 ATOM 3166 O OD2 . ASP A 1 412 ? 27.735 132.080 24.284 1.00 59.16 ? 464 ASP A OD2 1 ATOM 3167 N N . CYS A 1 413 ? 24.400 132.558 19.886 1.00 23.88 ? 465 CYS A N 1 ATOM 3168 C CA . CYS A 1 413 ? 22.966 132.343 19.743 1.00 21.90 ? 465 CYS A CA 1 ATOM 3169 C C . CYS A 1 413 ? 22.682 131.994 18.293 1.00 17.97 ? 465 CYS A C 1 ATOM 3170 O O . CYS A 1 413 ? 23.187 132.652 17.387 1.00 18.59 ? 465 CYS A O 1 ATOM 3171 C CB . CYS A 1 413 ? 22.175 133.593 20.160 1.00 19.17 ? 465 CYS A CB 1 ATOM 3172 S SG . CYS A 1 413 ? 20.436 133.625 19.634 1.00 24.81 ? 465 CYS A SG 1 ATOM 3173 N N . ASN A 1 414 ? 21.892 130.952 18.062 1.00 17.28 ? 466 ASN A N 1 ATOM 3174 C CA . ASN A 1 414 ? 21.343 130.738 16.733 1.00 16.82 ? 466 ASN A CA 1 ATOM 3175 C C . ASN A 1 414 ? 20.237 131.765 16.508 1.00 15.99 ? 466 ASN A C 1 ATOM 3176 O O . ASN A 1 414 ? 19.260 131.793 17.245 1.00 15.41 ? 466 ASN A O 1 ATOM 3177 C CB . ASN A 1 414 ? 20.804 129.320 16.572 1.00 17.84 ? 466 ASN A CB 1 ATOM 3178 C CG . ASN A 1 414 ? 20.360 129.030 15.154 1.00 19.68 ? 466 ASN A CG 1 ATOM 3179 O OD1 . ASN A 1 414 ? 19.448 129.677 14.634 1.00 17.69 ? 466 ASN A OD1 1 ATOM 3180 N ND2 . ASN A 1 414 ? 21.004 128.059 14.517 1.00 23.06 ? 466 ASN A ND2 1 ATOM 3181 N N . MET A 1 415 ? 20.393 132.613 15.495 1.00 14.48 ? 467 MET A N 1 ATOM 3182 C CA . MET A 1 415 ? 19.548 133.795 15.376 1.00 15.34 ? 467 MET A CA 1 ATOM 3183 C C . MET A 1 415 ? 18.175 133.518 14.775 1.00 15.79 ? 467 MET A C 1 ATOM 3184 O O . MET A 1 415 ? 17.380 134.432 14.591 1.00 16.05 ? 467 MET A O 1 ATOM 3185 C CB . MET A 1 415 ? 20.285 134.862 14.573 1.00 14.82 ? 467 MET A CB 1 ATOM 3186 C CG . MET A 1 415 ? 21.408 135.524 15.371 1.00 16.44 ? 467 MET A CG 1 ATOM 3187 S SD . MET A 1 415 ? 20.884 136.259 16.939 1.00 15.89 ? 467 MET A SD 1 ATOM 3188 C CE . MET A 1 415 ? 19.807 137.567 16.344 1.00 15.29 ? 467 MET A CE 1 ATOM 3189 N N . GLY A 1 416 ? 17.875 132.243 14.542 1.00 14.65 ? 468 GLY A N 1 ATOM 3190 C CA . GLY A 1 416 ? 16.526 131.823 14.199 1.00 17.26 ? 468 GLY A CA 1 ATOM 3191 C C . GLY A 1 416 ? 15.767 131.272 15.398 1.00 16.59 ? 468 GLY A C 1 ATOM 3192 O O . GLY A 1 416 ? 14.590 130.938 15.284 1.00 17.10 ? 468 GLY A O 1 ATOM 3193 N N . GLU A 1 417 ? 16.441 131.172 16.541 1.00 16.48 ? 469 GLU A N 1 ATOM 3194 C CA . GLU A 1 417 ? 15.839 130.654 17.768 1.00 17.34 ? 469 GLU A CA 1 ATOM 3195 C C . GLU A 1 417 ? 15.415 131.755 18.738 1.00 19.48 ? 469 GLU A C 1 ATOM 3196 O O . GLU A 1 417 ? 15.656 132.934 18.497 1.00 18.58 ? 469 GLU A O 1 ATOM 3197 C CB . GLU A 1 417 ? 16.814 129.702 18.453 1.00 18.74 ? 469 GLU A CB 1 ATOM 3198 C CG . GLU A 1 417 ? 17.216 128.537 17.559 1.00 18.25 ? 469 GLU A CG 1 ATOM 3199 C CD . GLU A 1 417 ? 16.033 127.680 17.158 1.00 20.13 ? 469 GLU A CD 1 ATOM 3200 O OE1 . GLU A 1 417 ? 15.233 127.321 18.049 1.00 23.54 ? 469 GLU A OE1 1 ATOM 3201 O OE2 . GLU A 1 417 ? 15.896 127.384 15.951 1.00 22.96 ? 469 GLU A OE2 1 ATOM 3202 N N . SER A 1 418 ? 14.792 131.363 19.845 1.00 19.39 ? 470 SER A N 1 ATOM 3203 C CA . SER A 1 418 ? 14.160 132.323 20.744 1.00 20.53 ? 470 SER A CA 1 ATOM 3204 C C . SER A 1 418 ? 15.176 133.249 21.409 1.00 21.96 ? 470 SER A C 1 ATOM 3205 O O . SER A 1 418 ? 14.826 134.334 21.864 1.00 24.29 ? 470 SER A O 1 ATOM 3206 C CB . SER A 1 418 ? 13.345 131.594 21.816 1.00 22.90 ? 470 SER A CB 1 ATOM 3207 O OG . SER A 1 418 ? 14.179 130.821 22.660 1.00 29.48 ? 470 SER A OG 1 ATOM 3208 N N . CYS A 1 419 ? 16.432 132.827 21.451 1.00 20.57 ? 471 CYS A N 1 ATOM 3209 C CA . CYS A 1 419 ? 17.484 133.649 22.037 1.00 21.34 ? 471 CYS A CA 1 ATOM 3210 C C . CYS A 1 419 ? 17.754 134.915 21.219 1.00 21.91 ? 471 CYS A C 1 ATOM 3211 O O . CYS A 1 419 ? 18.410 135.842 21.703 1.00 18.53 ? 471 CYS A O 1 ATOM 3212 C CB . CYS A 1 419 ? 18.772 132.836 22.167 1.00 24.42 ? 471 CYS A CB 1 ATOM 3213 S SG . CYS A 1 419 ? 19.407 132.152 20.601 1.00 25.44 ? 471 CYS A SG 1 ATOM 3214 N N . ALA A 1 420 ? 17.247 134.960 19.990 1.00 18.26 ? 472 ALA A N 1 ATOM 3215 C CA . ALA A 1 420 ? 17.592 136.038 19.066 1.00 17.16 ? 472 ALA A CA 1 ATOM 3216 C C . ALA A 1 420 ? 17.212 137.407 19.615 1.00 18.97 ? 472 ALA A C 1 ATOM 3217 O O . ALA A 1 420 ? 17.879 138.394 19.333 1.00 20.55 ? 472 ALA A O 1 ATOM 3218 C CB . ALA A 1 420 ? 16.924 135.808 17.712 1.00 18.23 ? 472 ALA A CB 1 ATOM 3219 N N . ALA A 1 421 ? 16.156 137.468 20.411 1.00 17.89 ? 473 ALA A N 1 ATOM 3220 C CA . ALA A 1 421 ? 15.656 138.754 20.887 1.00 21.56 ? 473 ALA A CA 1 ATOM 3221 C C . ALA A 1 421 ? 16.542 139.400 21.950 1.00 21.43 ? 473 ALA A C 1 ATOM 3222 O O . ALA A 1 421 ? 16.454 140.609 22.165 1.00 21.67 ? 473 ALA A O 1 ATOM 3223 C CB . ALA A 1 421 ? 14.254 138.594 21.427 1.00 26.43 ? 473 ALA A CB 1 ATOM 3224 N N . THR A 1 422 ? 17.383 138.609 22.616 1.00 17.61 ? 474 THR A N 1 ATOM 3225 C CA . THR A 1 422 ? 18.207 139.131 23.711 1.00 19.23 ? 474 THR A CA 1 ATOM 3226 C C . THR A 1 422 ? 19.696 138.880 23.517 1.00 19.56 ? 474 THR A C 1 ATOM 3227 O O . THR A 1 422 ? 20.509 139.343 24.312 1.00 22.90 ? 474 THR A O 1 ATOM 3228 C CB . THR A 1 422 ? 17.789 138.521 25.060 1.00 24.17 ? 474 THR A CB 1 ATOM 3229 O OG1 . THR A 1 422 ? 17.824 137.092 24.970 1.00 24.61 ? 474 THR A OG1 1 ATOM 3230 C CG2 . THR A 1 422 ? 16.388 138.981 25.445 1.00 24.22 ? 474 THR A CG2 1 ATOM 3231 N N . ALA A 1 423 ? 20.056 138.159 22.464 1.00 15.68 ? 475 ALA A N 1 ATOM 3232 C CA . ALA A 1 423 ? 21.452 137.841 22.201 1.00 15.98 ? 475 ALA A CA 1 ATOM 3233 C C . ALA A 1 423 ? 22.281 139.097 22.014 1.00 17.17 ? 475 ALA A C 1 ATOM 3234 O O . ALA A 1 423 ? 21.806 140.075 21.448 1.00 16.25 ? 475 ALA A O 1 ATOM 3235 C CB . ALA A 1 423 ? 21.572 136.970 20.974 1.00 19.56 ? 475 ALA A CB 1 ATOM 3236 N N . ARG A 1 424 ? 23.520 139.061 22.495 1.00 19.68 ? 476 ARG A N 1 ATOM 3237 C CA . ARG A 1 424 ? 24.464 140.125 22.201 1.00 17.00 ? 476 ARG A CA 1 ATOM 3238 C C . ARG A 1 424 ? 25.520 139.616 21.230 1.00 19.00 ? 476 ARG A C 1 ATOM 3239 O O . ARG A 1 424 ? 25.741 138.409 21.094 1.00 19.69 ? 476 ARG A O 1 ATOM 3240 C CB . ARG A 1 424 ? 25.091 140.665 23.487 1.00 22.24 ? 476 ARG A CB 1 ATOM 3241 C CG . ARG A 1 424 ? 24.053 141.336 24.403 1.00 26.56 ? 476 ARG A CG 1 ATOM 3242 C CD . ARG A 1 424 ? 24.581 142.587 25.090 1.00 30.58 ? 476 ARG A CD 1 ATOM 3243 N NE . ARG A 1 424 ? 23.487 143.360 25.682 1.00 37.95 ? 476 ARG A NE 1 ATOM 3244 C CZ . ARG A 1 424 ? 23.196 144.629 25.401 1.00 39.41 ? 476 ARG A CZ 1 ATOM 3245 N NH1 . ARG A 1 424 ? 23.919 145.333 24.533 1.00 28.43 ? 476 ARG A NH1 1 ATOM 3246 N NH2 . ARG A 1 424 ? 22.168 145.205 26.007 1.00 47.63 ? 476 ARG A NH2 1 ATOM 3247 N N . GLY A 1 425 ? 26.148 140.549 20.528 1.00 17.31 ? 477 GLY A N 1 ATOM 3248 C CA . GLY A 1 425 ? 27.140 140.218 19.536 1.00 16.41 ? 477 GLY A CA 1 ATOM 3249 C C . GLY A 1 425 ? 27.682 141.465 18.872 1.00 16.26 ? 477 GLY A C 1 ATOM 3250 O O . GLY A 1 425 ? 27.638 142.557 19.439 1.00 18.83 ? 477 GLY A O 1 ATOM 3251 N N . LYS A 1 426 ? 28.180 141.287 17.658 1.00 15.03 ? 478 LYS A N 1 ATOM 3252 C CA . LYS A 1 426 ? 28.864 142.338 16.931 1.00 15.94 ? 478 LYS A CA 1 ATOM 3253 C C . LYS A 1 426 ? 28.081 142.741 15.688 1.00 17.13 ? 478 LYS A C 1 ATOM 3254 O O . LYS A 1 426 ? 27.611 141.876 14.950 1.00 16.33 ? 478 LYS A O 1 ATOM 3255 C CB . LYS A 1 426 ? 30.259 141.858 16.550 1.00 21.42 ? 478 LYS A CB 1 ATOM 3256 C CG . LYS A 1 426 ? 31.266 142.956 16.340 1.00 24.42 ? 478 LYS A CG 1 ATOM 3257 C CD . LYS A 1 426 ? 32.665 142.368 16.304 1.00 23.24 ? 478 LYS A CD 1 ATOM 3258 C CE . LYS A 1 426 ? 33.734 143.423 16.447 1.00 39.37 ? 478 LYS A CE 1 ATOM 3259 N NZ . LYS A 1 426 ? 34.630 143.089 17.592 1.00 36.26 ? 478 LYS A NZ 1 ATOM 3260 N N . CYS A 1 427 ? 27.935 144.050 15.485 1.00 13.63 ? 479 CYS A N 1 ATOM 3261 C CA A CYS A 1 427 ? 27.294 144.599 14.298 0.43 14.00 ? 479 CYS A CA 1 ATOM 3262 C CA B CYS A 1 427 ? 27.326 144.605 14.274 0.57 13.94 ? 479 CYS A CA 1 ATOM 3263 C C . CYS A 1 427 ? 28.368 145.055 13.297 1.00 17.68 ? 479 CYS A C 1 ATOM 3264 O O . CYS A 1 427 ? 29.232 145.849 13.651 1.00 18.54 ? 479 CYS A O 1 ATOM 3265 C CB A CYS A 1 427 ? 26.377 145.763 14.708 0.43 16.00 ? 479 CYS A CB 1 ATOM 3266 C CB B CYS A 1 427 ? 26.470 145.820 14.569 0.57 15.85 ? 479 CYS A CB 1 ATOM 3267 S SG A CYS A 1 427 ? 25.155 146.320 13.489 0.43 14.69 ? 479 CYS A SG 1 ATOM 3268 S SG B CYS A 1 427 ? 25.524 145.768 16.042 0.57 21.99 ? 479 CYS A SG 1 ATOM 3269 N N . PHE A 1 428 ? 28.291 144.572 12.064 1.00 11.77 ? 480 PHE A N 1 ATOM 3270 C CA . PHE A 1 428 ? 29.196 145.001 11.003 1.00 12.18 ? 480 PHE A CA 1 ATOM 3271 C C . PHE A 1 428 ? 28.432 145.830 9.988 1.00 12.30 ? 480 PHE A C 1 ATOM 3272 O O . PHE A 1 428 ? 27.433 145.373 9.447 1.00 13.43 ? 480 PHE A O 1 ATOM 3273 C CB . PHE A 1 428 ? 29.851 143.801 10.320 1.00 14.64 ? 480 PHE A CB 1 ATOM 3274 C CG . PHE A 1 428 ? 30.726 143.005 11.231 1.00 15.60 ? 480 PHE A CG 1 ATOM 3275 C CD1 . PHE A 1 428 ? 32.055 143.343 11.408 1.00 14.81 ? 480 PHE A CD1 1 ATOM 3276 C CD2 . PHE A 1 428 ? 30.218 141.921 11.924 1.00 14.82 ? 480 PHE A CD2 1 ATOM 3277 C CE1 . PHE A 1 428 ? 32.857 142.611 12.252 1.00 18.37 ? 480 PHE A CE1 1 ATOM 3278 C CE2 . PHE A 1 428 ? 31.019 141.186 12.769 1.00 17.15 ? 480 PHE A CE2 1 ATOM 3279 C CZ . PHE A 1 428 ? 32.338 141.530 12.933 1.00 17.86 ? 480 PHE A CZ 1 ATOM 3280 N N . PHE A 1 429 ? 28.905 147.045 9.727 1.00 11.52 ? 481 PHE A N 1 ATOM 3281 C CA . PHE A 1 429 ? 28.215 147.984 8.847 1.00 10.21 ? 481 PHE A CA 1 ATOM 3282 C C . PHE A 1 429 ? 28.893 148.078 7.487 1.00 12.24 ? 481 PHE A C 1 ATOM 3283 O O . PHE A 1 429 ? 30.127 148.122 7.394 1.00 12.96 ? 481 PHE A O 1 ATOM 3284 C CB . PHE A 1 429 ? 28.162 149.380 9.489 1.00 13.44 ? 481 PHE A CB 1 ATOM 3285 C CG . PHE A 1 429 ? 27.448 149.433 10.805 1.00 13.05 ? 481 PHE A CG 1 ATOM 3286 C CD1 . PHE A 1 429 ? 26.067 149.413 10.861 1.00 12.74 ? 481 PHE A CD1 1 ATOM 3287 C CD2 . PHE A 1 429 ? 28.154 149.552 11.990 1.00 15.94 ? 481 PHE A CD2 1 ATOM 3288 C CE1 . PHE A 1 429 ? 25.403 149.481 12.071 1.00 17.35 ? 481 PHE A CE1 1 ATOM 3289 C CE2 . PHE A 1 429 ? 27.497 149.615 13.204 1.00 16.40 ? 481 PHE A CE2 1 ATOM 3290 C CZ . PHE A 1 429 ? 26.114 149.578 13.244 1.00 19.66 ? 481 PHE A CZ 1 ATOM 3291 N N . TYR A 1 430 ? 28.081 148.135 6.431 1.00 11.57 ? 482 TYR A N 1 ATOM 3292 C CA . TYR A 1 430 ? 28.570 148.143 5.061 1.00 11.45 ? 482 TYR A CA 1 ATOM 3293 C C . TYR A 1 430 ? 27.997 149.276 4.227 1.00 9.76 ? 482 TYR A C 1 ATOM 3294 O O . TYR A 1 430 ? 26.836 149.666 4.413 1.00 11.72 ? 482 TYR A O 1 ATOM 3295 C CB . TYR A 1 430 ? 28.217 146.825 4.378 1.00 12.08 ? 482 TYR A CB 1 ATOM 3296 C CG . TYR A 1 430 ? 28.635 145.590 5.135 1.00 12.46 ? 482 TYR A CG 1 ATOM 3297 C CD1 . TYR A 1 430 ? 29.962 145.189 5.180 1.00 14.38 ? 482 TYR A CD1 1 ATOM 3298 C CD2 . TYR A 1 430 ? 27.690 144.801 5.784 1.00 13.07 ? 482 TYR A CD2 1 ATOM 3299 C CE1 . TYR A 1 430 ? 30.334 144.050 5.860 1.00 16.30 ? 482 TYR A CE1 1 ATOM 3300 C CE2 . TYR A 1 430 ? 28.052 143.670 6.471 1.00 13.93 ? 482 TYR A CE2 1 ATOM 3301 C CZ . TYR A 1 430 ? 29.372 143.293 6.504 1.00 16.68 ? 482 TYR A CZ 1 ATOM 3302 O OH . TYR A 1 430 ? 29.719 142.157 7.188 1.00 15.82 ? 482 TYR A OH 1 ATOM 3303 N N . SER A 1 431 ? 28.797 149.753 3.270 1.00 12.05 ? 483 SER A N 1 ATOM 3304 C CA . SER A 1 431 ? 28.327 150.694 2.258 1.00 12.65 ? 483 SER A CA 1 ATOM 3305 C C . SER A 1 431 ? 28.435 150.119 0.841 1.00 13.86 ? 483 SER A C 1 ATOM 3306 O O . SER A 1 431 ? 28.220 150.836 -0.139 1.00 14.86 ? 483 SER A O 1 ATOM 3307 C CB . SER A 1 431 ? 29.105 152.008 2.345 1.00 14.91 ? 483 SER A CB 1 ATOM 3308 O OG . SER A 1 431 ? 30.477 151.800 2.068 1.00 16.61 ? 483 SER A OG 1 ATOM 3309 N N . THR A 1 432 ? 28.743 148.823 0.754 1.00 15.56 ? 484 THR A N 1 ATOM 3310 C CA . THR A 1 432 ? 28.875 148.094 -0.509 1.00 15.73 ? 484 THR A CA 1 ATOM 3311 C C . THR A 1 432 ? 27.549 147.442 -0.881 1.00 14.72 ? 484 THR A C 1 ATOM 3312 O O . THR A 1 432 ? 26.892 146.874 -0.017 1.00 15.22 ? 484 THR A O 1 ATOM 3313 C CB . THR A 1 432 ? 29.945 146.993 -0.414 1.00 20.17 ? 484 THR A CB 1 ATOM 3314 O OG1 . THR A 1 432 ? 31.207 147.563 -0.032 1.00 21.36 ? 484 THR A OG1 1 ATOM 3315 C CG2 . THR A 1 432 ? 30.099 146.259 -1.748 1.00 21.29 ? 484 THR A CG2 1 ATOM 3316 N N . VAL A 1 433 ? 27.169 147.516 -2.154 1.00 13.74 ? 485 VAL A N 1 ATOM 3317 C CA . VAL A 1 433 ? 25.944 146.878 -2.631 1.00 13.76 ? 485 VAL A CA 1 ATOM 3318 C C . VAL A 1 433 ? 26.124 145.359 -2.626 1.00 14.49 ? 485 VAL A C 1 ATOM 3319 O O . VAL A 1 433 ? 27.055 144.847 -3.249 1.00 14.60 ? 485 VAL A O 1 ATOM 3320 C CB . VAL A 1 433 ? 25.584 147.364 -4.041 1.00 14.01 ? 485 VAL A CB 1 ATOM 3321 C CG1 . VAL A 1 433 ? 24.412 146.575 -4.629 1.00 16.12 ? 485 VAL A CG1 1 ATOM 3322 C CG2 . VAL A 1 433 ? 25.255 148.840 -4.010 1.00 14.99 ? 485 VAL A CG2 1 ATOM 3323 N N . PRO A 1 434 ? 25.227 144.627 -1.940 1.00 12.32 ? 486 PRO A N 1 ATOM 3324 C CA . PRO A 1 434 ? 25.398 143.171 -1.854 1.00 13.34 ? 486 PRO A CA 1 ATOM 3325 C C . PRO A 1 434 ? 24.945 142.414 -3.106 1.00 12.46 ? 486 PRO A C 1 ATOM 3326 O O . PRO A 1 434 ? 24.044 142.866 -3.815 1.00 14.20 ? 486 PRO A O 1 ATOM 3327 C CB . PRO A 1 434 ? 24.526 142.795 -0.658 1.00 13.02 ? 486 PRO A CB 1 ATOM 3328 C CG . PRO A 1 434 ? 23.424 143.797 -0.679 1.00 13.27 ? 486 PRO A CG 1 ATOM 3329 C CD . PRO A 1 434 ? 24.077 145.093 -1.139 1.00 12.43 ? 486 PRO A CD 1 ATOM 3330 N N . GLU A 1 435 ? 25.563 141.260 -3.348 1.00 13.00 ? 487 GLU A N 1 ATOM 3331 C CA . GLU A 1 435 ? 25.275 140.456 -4.537 1.00 14.39 ? 487 GLU A CA 1 ATOM 3332 C C . GLU A 1 435 ? 24.843 139.039 -4.179 1.00 14.26 ? 487 GLU A C 1 ATOM 3333 O O . GLU A 1 435 ? 24.363 138.304 -5.033 1.00 14.96 ? 487 GLU A O 1 ATOM 3334 C CB . GLU A 1 435 ? 26.498 140.380 -5.446 1.00 14.44 ? 487 GLU A CB 1 ATOM 3335 C CG . GLU A 1 435 ? 27.033 141.726 -5.879 1.00 17.32 ? 487 GLU A CG 1 ATOM 3336 C CD . GLU A 1 435 ? 28.426 141.630 -6.479 1.00 20.60 ? 487 GLU A CD 1 ATOM 3337 O OE1 . GLU A 1 435 ? 28.977 140.510 -6.559 1.00 19.56 ? 487 GLU A OE1 1 ATOM 3338 O OE2 . GLU A 1 435 ? 28.981 142.685 -6.854 1.00 24.81 ? 487 GLU A OE2 1 ATOM 3339 N N . CYS A 1 436 ? 25.065 138.649 -2.931 1.00 14.48 ? 488 CYS A N 1 ATOM 3340 C CA . CYS A 1 436 ? 24.732 137.310 -2.472 1.00 14.31 ? 488 CYS A CA 1 ATOM 3341 C C . CYS A 1 436 ? 24.698 137.254 -0.956 1.00 16.15 ? 488 CYS A C 1 ATOM 3342 O O . CYS A 1 436 ? 25.038 138.223 -0.278 1.00 15.03 ? 488 CYS A O 1 ATOM 3343 C CB . CYS A 1 436 ? 25.734 136.279 -3.009 1.00 17.84 ? 488 CYS A CB 1 ATOM 3344 S SG . CYS A 1 436 ? 27.495 136.646 -2.641 1.00 19.95 ? 488 CYS A SG 1 ATOM 3345 N N . LEU A 1 437 ? 24.269 136.111 -0.434 1.00 14.84 ? 489 LEU A N 1 ATOM 3346 C CA . LEU A 1 437 ? 24.193 135.880 0.998 1.00 13.56 ? 489 LEU A CA 1 ATOM 3347 C C . LEU A 1 437 ? 24.879 134.571 1.361 1.00 17.03 ? 489 LEU A C 1 ATOM 3348 O O . LEU A 1 437 ? 24.868 133.612 0.585 1.00 16.26 ? 489 LEU A O 1 ATOM 3349 C CB . LEU A 1 437 ? 22.733 135.859 1.462 1.00 14.91 ? 489 LEU A CB 1 ATOM 3350 C CG . LEU A 1 437 ? 21.967 137.166 1.273 1.00 16.59 ? 489 LEU A CG 1 ATOM 3351 C CD1 . LEU A 1 437 ? 20.470 136.927 1.408 1.00 15.27 ? 489 LEU A CD1 1 ATOM 3352 C CD2 . LEU A 1 437 ? 22.436 138.204 2.276 1.00 15.25 ? 489 LEU A CD2 1 ATOM 3353 N N . ILE A 1 438 ? 25.484 134.546 2.542 1.00 15.12 ? 490 ILE A N 1 ATOM 3354 C CA . ILE A 1 438 ? 26.118 133.353 3.086 1.00 15.34 ? 490 ILE A CA 1 ATOM 3355 C C . ILE A 1 438 ? 25.306 132.880 4.275 1.00 14.53 ? 490 ILE A C 1 ATOM 3356 O O . ILE A 1 438 ? 25.009 133.669 5.162 1.00 14.92 ? 490 ILE A O 1 ATOM 3357 C CB . ILE A 1 438 ? 27.565 133.632 3.555 1.00 17.01 ? 490 ILE A CB 1 ATOM 3358 C CG1 . ILE A 1 438 ? 28.419 134.158 2.404 1.00 20.50 ? 490 ILE A CG1 1 ATOM 3359 C CG2 . ILE A 1 438 ? 28.198 132.385 4.167 1.00 19.62 ? 490 ILE A CG2 1 ATOM 3360 C CD1 . ILE A 1 438 ? 29.723 134.790 2.869 1.00 21.18 ? 490 ILE A CD1 1 ATOM 3361 N N . HIS A 1 439 ? 24.963 131.596 4.319 1.00 15.33 ? 491 HIS A N 1 ATOM 3362 C CA . HIS A 1 439 ? 24.231 131.066 5.458 1.00 16.05 ? 491 HIS A CA 1 ATOM 3363 C C . HIS A 1 439 ? 25.123 130.925 6.682 1.00 15.43 ? 491 HIS A C 1 ATOM 3364 O O . HIS A 1 439 ? 26.282 130.513 6.579 1.00 20.10 ? 491 HIS A O 1 ATOM 3365 C CB . HIS A 1 439 ? 23.619 129.702 5.128 1.00 19.52 ? 491 HIS A CB 1 ATOM 3366 C CG . HIS A 1 439 ? 22.752 129.160 6.220 1.00 24.49 ? 491 HIS A CG 1 ATOM 3367 N ND1 . HIS A 1 439 ? 23.225 128.303 7.191 1.00 30.96 ? 491 HIS A ND1 1 ATOM 3368 C CD2 . HIS A 1 439 ? 21.447 129.377 6.512 1.00 23.10 ? 491 HIS A CD2 1 ATOM 3369 C CE1 . HIS A 1 439 ? 22.245 128.005 8.026 1.00 28.70 ? 491 HIS A CE1 1 ATOM 3370 N NE2 . HIS A 1 439 ? 21.154 128.641 7.633 1.00 29.45 ? 491 HIS A NE2 1 ATOM 3371 N N . SER A 1 440 ? 24.575 131.262 7.842 1.00 15.37 ? 492 SER A N 1 ATOM 3372 C CA . SER A 1 440 ? 25.248 131.027 9.104 1.00 16.01 ? 492 SER A CA 1 ATOM 3373 C C . SER A 1 440 ? 24.247 130.857 10.227 1.00 15.34 ? 492 SER A C 1 ATOM 3374 O O . SER A 1 440 ? 23.227 131.549 10.272 1.00 18.69 ? 492 SER A O 1 ATOM 3375 C CB . SER A 1 440 ? 26.192 132.173 9.448 1.00 19.72 ? 492 SER A CB 1 ATOM 3376 O OG . SER A 1 440 ? 26.647 132.040 10.787 1.00 19.58 ? 492 SER A OG 1 ATOM 3377 N N . PRO A 1 441 ? 24.535 129.952 11.166 1.00 15.08 ? 493 PRO A N 1 ATOM 3378 C CA . PRO A 1 441 ? 23.585 129.812 12.270 1.00 18.10 ? 493 PRO A CA 1 ATOM 3379 C C . PRO A 1 441 ? 23.513 131.026 13.194 1.00 15.08 ? 493 PRO A C 1 ATOM 3380 O O . PRO A 1 441 ? 22.474 131.231 13.804 1.00 16.41 ? 493 PRO A O 1 ATOM 3381 C CB . PRO A 1 441 ? 24.110 128.592 13.033 1.00 21.07 ? 493 PRO A CB 1 ATOM 3382 C CG . PRO A 1 441 ? 25.536 128.458 12.639 1.00 25.45 ? 493 PRO A CG 1 ATOM 3383 C CD . PRO A 1 441 ? 25.625 128.961 11.235 1.00 19.99 ? 493 PRO A CD 1 ATOM 3384 N N . THR A 1 442 ? 24.576 131.821 13.285 1.00 15.08 ? 494 THR A N 1 ATOM 3385 C CA . THR A 1 442 ? 24.651 132.820 14.343 1.00 14.70 ? 494 THR A CA 1 ATOM 3386 C C . THR A 1 442 ? 24.535 134.258 13.845 1.00 14.30 ? 494 THR A C 1 ATOM 3387 O O . THR A 1 442 ? 24.899 135.185 14.563 1.00 16.73 ? 494 THR A O 1 ATOM 3388 C CB . THR A 1 442 ? 25.962 132.669 15.140 1.00 18.84 ? 494 THR A CB 1 ATOM 3389 O OG1 . THR A 1 442 ? 27.080 132.746 14.248 1.00 23.18 ? 494 THR A OG1 1 ATOM 3390 C CG2 . THR A 1 442 ? 25.981 131.324 15.864 1.00 19.94 ? 494 THR A CG2 1 ATOM 3391 N N . THR A 1 443 ? 23.984 134.449 12.649 1.00 12.55 ? 495 THR A N 1 ATOM 3392 C CA . THR A 1 443 ? 23.916 135.788 12.072 1.00 10.95 ? 495 THR A CA 1 ATOM 3393 C C . THR A 1 443 ? 22.509 136.213 11.647 1.00 13.42 ? 495 THR A C 1 ATOM 3394 O O . THR A 1 443 ? 21.593 135.401 11.529 1.00 13.81 ? 495 THR A O 1 ATOM 3395 C CB . THR A 1 443 ? 24.846 135.909 10.861 1.00 12.71 ? 495 THR A CB 1 ATOM 3396 O OG1 . THR A 1 443 ? 24.352 135.100 9.788 1.00 14.59 ? 495 THR A OG1 1 ATOM 3397 C CG2 . THR A 1 443 ? 26.249 135.469 11.229 1.00 14.07 ? 495 THR A CG2 1 ATOM 3398 N N . MET A 1 444 ? 22.367 137.516 11.420 1.00 13.96 ? 496 MET A N 1 ATOM 3399 C CA . MET A 1 444 ? 21.126 138.118 10.944 1.00 12.96 ? 496 MET A CA 1 ATOM 3400 C C . MET A 1 444 ? 21.507 139.332 10.127 1.00 14.54 ? 496 MET A C 1 ATOM 3401 O O . MET A 1 444 ? 22.433 140.054 10.505 1.00 13.67 ? 496 MET A O 1 ATOM 3402 C CB . MET A 1 444 ? 20.208 138.516 12.105 1.00 12.93 ? 496 MET A CB 1 ATOM 3403 C CG . MET A 1 444 ? 18.871 139.131 11.678 1.00 13.18 ? 496 MET A CG 1 ATOM 3404 S SD . MET A 1 444 ? 17.734 139.308 13.046 1.00 13.88 ? 496 MET A SD 1 ATOM 3405 C CE . MET A 1 444 ? 17.376 137.589 13.422 1.00 14.22 ? 496 MET A CE 1 ATOM 3406 N N . ALA A 1 445 ? 20.806 139.549 9.019 1.00 11.15 ? 497 ALA A N 1 ATOM 3407 C CA . ALA A 1 445 ? 21.110 140.642 8.103 1.00 10.48 ? 497 ALA A CA 1 ATOM 3408 C C . ALA A 1 445 ? 20.000 141.684 8.118 1.00 12.79 ? 497 ALA A C 1 ATOM 3409 O O . ALA A 1 445 ? 18.819 141.351 8.004 1.00 12.83 ? 497 ALA A O 1 ATOM 3410 C CB . ALA A 1 445 ? 21.322 140.113 6.696 1.00 12.18 ? 497 ALA A CB 1 ATOM 3411 N N . PHE A 1 446 ? 20.404 142.950 8.244 1.00 12.00 ? 498 PHE A N 1 ATOM 3412 C CA . PHE A 1 446 ? 19.508 144.101 8.249 1.00 11.88 ? 498 PHE A CA 1 ATOM 3413 C C . PHE A 1 446 ? 19.804 145.048 7.098 1.00 10.04 ? 498 PHE A C 1 ATOM 3414 O O . PHE A 1 446 ? 20.950 145.135 6.640 1.00 10.66 ? 498 PHE A O 1 ATOM 3415 C CB . PHE A 1 446 ? 19.646 144.904 9.551 1.00 13.17 ? 498 PHE A CB 1 ATOM 3416 C CG . PHE A 1 446 ? 19.224 144.174 10.798 1.00 11.20 ? 498 PHE A CG 1 ATOM 3417 C CD1 . PHE A 1 446 ? 20.114 143.344 11.466 1.00 14.73 ? 498 PHE A CD1 1 ATOM 3418 C CD2 . PHE A 1 446 ? 17.956 144.350 11.332 1.00 11.09 ? 498 PHE A CD2 1 ATOM 3419 C CE1 . PHE A 1 446 ? 19.732 142.682 12.627 1.00 14.14 ? 498 PHE A CE1 1 ATOM 3420 C CE2 . PHE A 1 446 ? 17.574 143.694 12.502 1.00 12.16 ? 498 PHE A CE2 1 ATOM 3421 C CZ . PHE A 1 446 ? 18.463 142.858 13.144 1.00 13.83 ? 498 PHE A CZ 1 ATOM 3422 N N . THR A 1 447 ? 18.776 145.769 6.641 1.00 10.82 ? 499 THR A N 1 ATOM 3423 C CA . THR A 1 447 ? 18.976 146.961 5.816 1.00 10.08 ? 499 THR A CA 1 ATOM 3424 C C . THR A 1 447 ? 18.427 148.180 6.553 1.00 9.30 ? 499 THR A C 1 ATOM 3425 O O . THR A 1 447 ? 17.683 148.065 7.522 1.00 9.82 ? 499 THR A O 1 ATOM 3426 C CB . THR A 1 447 ? 18.299 146.902 4.418 1.00 11.69 ? 499 THR A CB 1 ATOM 3427 O OG1 . THR A 1 447 ? 16.908 147.245 4.523 1.00 11.51 ? 499 THR A OG1 1 ATOM 3428 C CG2 . THR A 1 447 ? 18.498 145.546 3.749 1.00 12.12 ? 499 THR A CG2 1 ATOM 3429 N N . SER A 1 448 ? 18.790 149.358 6.062 1.00 10.81 ? 500 SER A N 1 ATOM 3430 C CA . SER A 1 448 ? 18.331 150.602 6.654 1.00 10.08 ? 500 SER A CA 1 ATOM 3431 C C . SER A 1 448 ? 16.838 150.857 6.479 1.00 9.86 ? 500 SER A C 1 ATOM 3432 O O . SER A 1 448 ? 16.284 151.738 7.131 1.00 11.57 ? 500 SER A O 1 ATOM 3433 C CB . SER A 1 448 ? 19.133 151.763 6.065 1.00 10.39 ? 500 SER A CB 1 ATOM 3434 O OG . SER A 1 448 ? 19.061 151.784 4.657 1.00 11.02 ? 500 SER A OG 1 ATOM 3435 N N . LEU A 1 449 ? 16.199 150.092 5.594 1.00 9.64 ? 501 LEU A N 1 ATOM 3436 C CA . LEU A 1 449 ? 14.752 150.171 5.365 1.00 10.06 ? 501 LEU A CA 1 ATOM 3437 C C . LEU A 1 449 ? 13.980 149.029 6.042 1.00 11.46 ? 501 LEU A C 1 ATOM 3438 O O . LEU A 1 449 ? 12.749 148.982 5.961 1.00 11.49 ? 501 LEU A O 1 ATOM 3439 C CB . LEU A 1 449 ? 14.479 150.175 3.856 1.00 10.85 ? 501 LEU A CB 1 ATOM 3440 C CG . LEU A 1 449 ? 14.874 151.460 3.116 1.00 11.06 ? 501 LEU A CG 1 ATOM 3441 C CD1 . LEU A 1 449 ? 14.981 151.205 1.635 1.00 11.51 ? 501 LEU A CD1 1 ATOM 3442 C CD2 . LEU A 1 449 ? 13.873 152.572 3.386 1.00 10.55 ? 501 LEU A CD2 1 ATOM 3443 N N . SER A 1 450 ? 14.700 148.127 6.704 1.00 10.90 ? 502 SER A N 1 ATOM 3444 C CA . SER A 1 450 ? 14.092 146.975 7.393 1.00 10.54 ? 502 SER A CA 1 ATOM 3445 C C . SER A 1 450 ? 13.508 147.353 8.749 1.00 11.39 ? 502 SER A C 1 ATOM 3446 O O . SER A 1 450 ? 13.998 148.268 9.418 1.00 12.13 ? 502 SER A O 1 ATOM 3447 C CB . SER A 1 450 ? 15.126 145.866 7.631 1.00 10.72 ? 502 SER A CB 1 ATOM 3448 O OG . SER A 1 450 ? 15.844 145.520 6.467 1.00 13.10 ? 502 SER A OG 1 ATOM 3449 N N . ALA A 1 451 ? 12.480 146.626 9.180 1.00 11.93 ? 503 ALA A N 1 ATOM 3450 C CA . ALA A 1 451 ? 12.102 146.645 10.590 1.00 10.83 ? 503 ALA A CA 1 ATOM 3451 C C . ALA A 1 451 ? 13.252 146.050 11.422 1.00 11.28 ? 503 ALA A C 1 ATOM 3452 O O . ALA A 1 451 ? 14.118 145.347 10.883 1.00 13.62 ? 503 ALA A O 1 ATOM 3453 C CB . ALA A 1 451 ? 10.809 145.883 10.815 1.00 11.80 ? 503 ALA A CB 1 ATOM 3454 N N . VAL A 1 452 ? 13.262 146.326 12.725 1.00 12.23 ? 504 VAL A N 1 ATOM 3455 C CA . VAL A 1 452 ? 14.405 145.948 13.562 1.00 11.54 ? 504 VAL A CA 1 ATOM 3456 C C . VAL A 1 452 ? 14.119 144.883 14.615 1.00 15.22 ? 504 VAL A C 1 ATOM 3457 O O . VAL A 1 452 ? 14.963 144.627 15.457 1.00 16.28 ? 504 VAL A O 1 ATOM 3458 C CB . VAL A 1 452 ? 15.011 147.185 14.285 1.00 12.00 ? 504 VAL A CB 1 ATOM 3459 C CG1 . VAL A 1 452 ? 15.429 148.234 13.270 1.00 14.17 ? 504 VAL A CG1 1 ATOM 3460 C CG2 . VAL A 1 452 ? 14.048 147.786 15.302 1.00 11.42 ? 504 VAL A CG2 1 ATOM 3461 N N . ASP A 1 453 ? 12.951 144.244 14.561 1.00 13.11 ? 505 ASP A N 1 ATOM 3462 C CA . ASP A 1 453 ? 12.636 143.153 15.484 1.00 14.93 ? 505 ASP A CA 1 ATOM 3463 C C . ASP A 1 453 ? 13.270 141.848 15.003 1.00 15.18 ? 505 ASP A C 1 ATOM 3464 O O . ASP A 1 453 ? 12.857 141.299 13.991 1.00 14.37 ? 505 ASP A O 1 ATOM 3465 C CB . ASP A 1 453 ? 11.123 142.987 15.608 1.00 13.97 ? 505 ASP A CB 1 ATOM 3466 C CG . ASP A 1 453 ? 10.721 142.003 16.699 1.00 17.75 ? 505 ASP A CG 1 ATOM 3467 O OD1 . ASP A 1 453 ? 11.602 141.336 17.291 1.00 15.63 ? 505 ASP A OD1 1 ATOM 3468 O OD2 . ASP A 1 453 ? 9.506 141.899 16.961 1.00 19.51 ? 505 ASP A OD2 1 ATOM 3469 N N . PRO A 1 454 ? 14.283 141.339 15.723 1.00 13.52 ? 506 PRO A N 1 ATOM 3470 C CA . PRO A 1 454 ? 14.887 140.097 15.237 1.00 12.64 ? 506 PRO A CA 1 ATOM 3471 C C . PRO A 1 454 ? 13.929 138.905 15.297 1.00 13.96 ? 506 PRO A C 1 ATOM 3472 O O . PRO A 1 454 ? 14.151 137.926 14.583 1.00 13.25 ? 506 PRO A O 1 ATOM 3473 C CB . PRO A 1 454 ? 16.080 139.896 16.184 1.00 14.91 ? 506 PRO A CB 1 ATOM 3474 C CG . PRO A 1 454 ? 15.742 140.659 17.401 1.00 18.61 ? 506 PRO A CG 1 ATOM 3475 C CD . PRO A 1 454 ? 14.943 141.839 16.945 1.00 14.70 ? 506 PRO A CD 1 ATOM 3476 N N . SER A 1 455 ? 12.873 138.997 16.101 1.00 13.71 ? 507 SER A N 1 ATOM 3477 C CA A SER A 1 455 ? 11.972 137.867 16.312 0.35 14.70 ? 507 SER A CA 1 ATOM 3478 C CA B SER A 1 455 ? 11.988 137.852 16.306 0.65 14.60 ? 507 SER A CA 1 ATOM 3479 C C . SER A 1 455 ? 11.047 137.614 15.124 1.00 17.65 ? 507 SER A C 1 ATOM 3480 O O . SER A 1 455 ? 10.412 136.559 15.042 1.00 18.11 ? 507 SER A O 1 ATOM 3481 C CB A SER A 1 455 ? 11.136 138.087 17.573 0.35 16.95 ? 507 SER A CB 1 ATOM 3482 C CB B SER A 1 455 ? 11.172 138.024 17.592 0.65 16.86 ? 507 SER A CB 1 ATOM 3483 O OG A SER A 1 455 ? 11.955 138.105 18.729 0.35 17.60 ? 507 SER A OG 1 ATOM 3484 O OG B SER A 1 455 ? 10.140 138.986 17.447 0.65 18.13 ? 507 SER A OG 1 ATOM 3485 N N . ILE A 1 456 ? 10.958 138.574 14.205 1.00 12.76 ? 508 ILE A N 1 ATOM 3486 C CA . ILE A 1 456 ? 10.138 138.390 13.002 1.00 13.28 ? 508 ILE A CA 1 ATOM 3487 C C . ILE A 1 456 ? 10.979 138.036 11.778 1.00 11.73 ? 508 ILE A C 1 ATOM 3488 O O . ILE A 1 456 ? 10.452 137.924 10.668 1.00 14.32 ? 508 ILE A O 1 ATOM 3489 C CB . ILE A 1 456 ? 9.290 139.645 12.665 1.00 14.17 ? 508 ILE A CB 1 ATOM 3490 C CG1 . ILE A 1 456 ? 10.161 140.825 12.205 1.00 15.09 ? 508 ILE A CG1 1 ATOM 3491 C CG2 . ILE A 1 456 ? 8.430 140.025 13.877 1.00 17.74 ? 508 ILE A CG2 1 ATOM 3492 C CD1 . ILE A 1 456 ? 9.358 142.036 11.770 1.00 15.08 ? 508 ILE A CD1 1 ATOM 3493 N N . ALA A 1 457 ? 12.283 137.854 11.967 1.00 11.82 ? 509 ALA A N 1 ATOM 3494 C CA . ALA A 1 457 ? 13.160 137.606 10.837 1.00 12.30 ? 509 ALA A CA 1 ATOM 3495 C C . ALA A 1 457 ? 12.749 136.355 10.066 1.00 13.38 ? 509 ALA A C 1 ATOM 3496 O O . ALA A 1 457 ? 12.313 135.358 10.649 1.00 14.52 ? 509 ALA A O 1 ATOM 3497 C CB . ALA A 1 457 ? 14.608 137.479 11.300 1.00 13.55 ? 509 ALA A CB 1 ATOM 3498 N N . ILE A 1 458 ? 12.902 136.420 8.752 1.00 13.04 ? 510 ILE A N 1 ATOM 3499 C CA . ILE A 1 458 ? 12.633 135.271 7.897 1.00 14.40 ? 510 ILE A CA 1 ATOM 3500 C C . ILE A 1 458 ? 13.778 135.022 6.920 1.00 16.01 ? 510 ILE A C 1 ATOM 3501 O O . ILE A 1 458 ? 14.765 135.755 6.884 1.00 13.47 ? 510 ILE A O 1 ATOM 3502 C CB . ILE A 1 458 ? 11.310 135.443 7.116 1.00 18.78 ? 510 ILE A CB 1 ATOM 3503 C CG1 . ILE A 1 458 ? 11.405 136.616 6.142 1.00 18.66 ? 510 ILE A CG1 1 ATOM 3504 C CG2 . ILE A 1 458 ? 10.147 135.627 8.076 1.00 19.17 ? 510 ILE A CG2 1 ATOM 3505 C CD1 . ILE A 1 458 ? 10.149 136.805 5.264 1.00 20.74 ? 510 ILE A CD1 1 ATOM 3506 N N . ASP A 1 459 ? 13.661 133.960 6.139 1.00 13.30 ? 511 ASP A N 1 ATOM 3507 C CA . ASP A 1 459 ? 14.677 133.627 5.153 1.00 13.14 ? 511 ASP A CA 1 ATOM 3508 C C . ASP A 1 459 ? 14.616 134.524 3.932 1.00 14.33 ? 511 ASP A C 1 ATOM 3509 O O . ASP A 1 459 ? 13.541 134.962 3.533 1.00 14.27 ? 511 ASP A O 1 ATOM 3510 C CB . ASP A 1 459 ? 14.518 132.182 4.695 1.00 15.54 ? 511 ASP A CB 1 ATOM 3511 C CG . ASP A 1 459 ? 14.634 131.205 5.826 1.00 17.26 ? 511 ASP A CG 1 ATOM 3512 O OD1 . ASP A 1 459 ? 15.665 131.232 6.528 1.00 16.17 ? 511 ASP A OD1 1 ATOM 3513 O OD2 . ASP A 1 459 ? 13.692 130.404 6.012 1.00 19.15 ? 511 ASP A OD2 1 ATOM 3514 N N . PRO A 1 460 ? 15.773 134.777 3.314 1.00 13.88 ? 512 PRO A N 1 ATOM 3515 C CA . PRO A 1 460 ? 15.763 135.331 1.964 1.00 12.59 ? 512 PRO A CA 1 ATOM 3516 C C . PRO A 1 460 ? 15.332 134.257 0.982 1.00 16.37 ? 512 PRO A C 1 ATOM 3517 O O . PRO A 1 460 ? 15.252 133.090 1.363 1.00 15.06 ? 512 PRO A O 1 ATOM 3518 C CB . PRO A 1 460 ? 17.216 135.719 1.735 1.00 15.59 ? 512 PRO A CB 1 ATOM 3519 C CG . PRO A 1 460 ? 17.969 134.678 2.512 1.00 14.09 ? 512 PRO A CG 1 ATOM 3520 C CD . PRO A 1 460 ? 17.134 134.400 3.737 1.00 15.07 ? 512 PRO A CD 1 ATOM 3521 N N . ASP A 1 461 ? 15.064 134.636 -0.257 1.00 15.88 ? 513 ASP A N 1 ATOM 3522 C CA . ASP A 1 461 ? 14.934 133.652 -1.326 1.00 15.31 ? 513 ASP A CA 1 ATOM 3523 C C . ASP A 1 461 ? 16.253 132.883 -1.441 1.00 17.29 ? 513 ASP A C 1 ATOM 3524 O O . ASP A 1 461 ? 17.329 133.485 -1.467 1.00 15.48 ? 513 ASP A O 1 ATOM 3525 C CB . ASP A 1 461 ? 14.569 134.343 -2.643 1.00 15.30 ? 513 ASP A CB 1 ATOM 3526 C CG . ASP A 1 461 ? 14.119 133.369 -3.718 1.00 20.23 ? 513 ASP A CG 1 ATOM 3527 O OD1 . ASP A 1 461 ? 14.849 132.398 -4.001 1.00 16.35 ? 513 ASP A OD1 1 ATOM 3528 O OD2 . ASP A 1 461 ? 13.027 133.591 -4.282 1.00 29.69 ? 513 ASP A OD2 1 ATOM 3529 N N . SER A 1 462 ? 16.180 131.556 -1.494 1.00 13.88 ? 514 SER A N 1 ATOM 3530 C CA . SER A 1 462 ? 17.383 130.728 -1.534 1.00 13.88 ? 514 SER A CA 1 ATOM 3531 C C . SER A 1 462 ? 18.251 130.981 -2.779 1.00 15.66 ? 514 SER A C 1 ATOM 3532 O O . SER A 1 462 ? 19.429 130.623 -2.787 1.00 15.66 ? 514 SER A O 1 ATOM 3533 C CB . SER A 1 462 ? 17.006 129.241 -1.454 1.00 15.91 ? 514 SER A CB 1 ATOM 3534 O OG . SER A 1 462 ? 16.174 128.856 -2.528 1.00 17.06 ? 514 SER A OG 1 ATOM 3535 N N . ILE A 1 463 ? 17.687 131.606 -3.811 1.00 14.95 ? 515 ILE A N 1 ATOM 3536 C CA . ILE A 1 463 ? 18.471 131.990 -4.985 1.00 15.52 ? 515 ILE A CA 1 ATOM 3537 C C . ILE A 1 463 ? 19.655 132.889 -4.608 1.00 16.91 ? 515 ILE A C 1 ATOM 3538 O O . ILE A 1 463 ? 20.683 132.902 -5.290 1.00 18.60 ? 515 ILE A O 1 ATOM 3539 C CB . ILE A 1 463 ? 17.592 132.714 -6.026 1.00 14.82 ? 515 ILE A CB 1 ATOM 3540 C CG1 . ILE A 1 463 ? 18.319 132.873 -7.370 1.00 20.37 ? 515 ILE A CG1 1 ATOM 3541 C CG2 . ILE A 1 463 ? 17.160 134.088 -5.536 1.00 18.08 ? 515 ILE A CG2 1 ATOM 3542 C CD1 . ILE A 1 463 ? 18.780 131.570 -8.000 1.00 20.87 ? 515 ILE A CD1 1 ATOM 3543 N N . ALA A 1 464 ? 19.514 133.614 -3.505 1.00 15.86 ? 516 ALA A N 1 ATOM 3544 C CA . ALA A 1 464 ? 20.558 134.545 -3.048 1.00 17.93 ? 516 ALA A CA 1 ATOM 3545 C C . ALA A 1 464 ? 21.761 133.870 -2.403 1.00 20.04 ? 516 ALA A C 1 ATOM 3546 O O . ALA A 1 464 ? 22.846 134.450 -2.351 1.00 16.92 ? 516 ALA A O 1 ATOM 3547 C CB . ALA A 1 464 ? 19.966 135.524 -2.070 1.00 16.22 ? 516 ALA A CB 1 ATOM 3548 N N . VAL A 1 465 ? 21.573 132.653 -1.902 1.00 15.05 ? 517 VAL A N 1 ATOM 3549 C CA . VAL A 1 465 ? 22.540 132.027 -1.020 1.00 16.13 ? 517 VAL A CA 1 ATOM 3550 C C . VAL A 1 465 ? 23.541 131.177 -1.801 1.00 23.04 ? 517 VAL A C 1 ATOM 3551 O O . VAL A 1 465 ? 23.164 130.356 -2.640 1.00 20.40 ? 517 VAL A O 1 ATOM 3552 C CB . VAL A 1 465 ? 21.813 131.184 0.052 1.00 18.63 ? 517 VAL A CB 1 ATOM 3553 C CG1 . VAL A 1 465 ? 22.799 130.484 0.959 1.00 20.51 ? 517 VAL A CG1 1 ATOM 3554 C CG2 . VAL A 1 465 ? 20.895 132.069 0.885 1.00 21.09 ? 517 VAL A CG2 1 ATOM 3555 N N . LEU A 1 466 ? 24.823 131.417 -1.540 1.00 17.87 ? 518 LEU A N 1 ATOM 3556 C CA . LEU A 1 466 ? 25.912 130.641 -2.133 1.00 17.27 ? 518 LEU A CA 1 ATOM 3557 C C . LEU A 1 466 ? 26.849 130.166 -1.033 1.00 20.10 ? 518 LEU A C 1 ATOM 3558 O O . LEU A 1 466 ? 26.938 130.788 0.025 1.00 18.74 ? 518 LEU A O 1 ATOM 3559 C CB . LEU A 1 466 ? 26.695 131.467 -3.159 1.00 18.22 ? 518 LEU A CB 1 ATOM 3560 C CG . LEU A 1 466 ? 25.981 131.838 -4.450 1.00 18.49 ? 518 LEU A CG 1 ATOM 3561 C CD1 . LEU A 1 466 ? 26.812 132.838 -5.248 1.00 23.20 ? 518 LEU A CD1 1 ATOM 3562 C CD2 . LEU A 1 466 ? 25.692 130.601 -5.285 1.00 24.93 ? 518 LEU A CD2 1 ATOM 3563 N N . PRO A 1 467 ? 27.563 129.055 -1.277 1.00 18.92 ? 519 PRO A N 1 ATOM 3564 C CA . PRO A 1 467 ? 28.584 128.627 -0.317 1.00 21.24 ? 519 PRO A CA 1 ATOM 3565 C C . PRO A 1 467 ? 29.678 129.680 -0.176 1.00 18.88 ? 519 PRO A C 1 ATOM 3566 O O . PRO A 1 467 ? 29.994 130.369 -1.153 1.00 20.44 ? 519 PRO A O 1 ATOM 3567 C CB . PRO A 1 467 ? 29.133 127.331 -0.929 1.00 23.57 ? 519 PRO A CB 1 ATOM 3568 C CG . PRO A 1 467 ? 28.763 127.392 -2.376 1.00 27.10 ? 519 PRO A CG 1 ATOM 3569 C CD . PRO A 1 467 ? 27.492 128.174 -2.453 1.00 22.73 ? 519 PRO A CD 1 ATOM 3570 N N . GLU A 1 468 ? 30.243 129.800 1.020 1.00 21.85 ? 520 GLU A N 1 ATOM 3571 C CA . GLU A 1 468 ? 31.279 130.788 1.266 1.00 22.76 ? 520 GLU A CA 1 ATOM 3572 C C . GLU A 1 468 ? 32.574 130.404 0.568 1.00 22.33 ? 520 GLU A C 1 ATOM 3573 O O . GLU A 1 468 ? 32.964 129.235 0.551 1.00 25.37 ? 520 GLU A O 1 ATOM 3574 C CB . GLU A 1 468 ? 31.534 130.965 2.771 1.00 23.28 ? 520 GLU A CB 1 ATOM 3575 C CG . GLU A 1 468 ? 32.685 131.933 3.071 1.00 24.16 ? 520 GLU A CG 1 ATOM 3576 C CD . GLU A 1 468 ? 32.834 132.273 4.546 1.00 27.88 ? 520 GLU A CD 1 ATOM 3577 O OE1 . GLU A 1 468 ? 32.114 131.689 5.381 1.00 29.24 ? 520 GLU A OE1 1 ATOM 3578 O OE2 . GLU A 1 468 ? 33.684 133.133 4.866 1.00 33.60 ? 520 GLU A OE2 1 ATOM 3579 N N . ASP A 1 469 ? 33.218 131.395 -0.037 1.00 22.94 ? 521 ASP A N 1 ATOM 3580 C CA . ASP A 1 469 ? 34.601 131.255 -0.467 1.00 24.95 ? 521 ASP A CA 1 ATOM 3581 C C . ASP A 1 469 ? 35.487 131.348 0.770 1.00 29.80 ? 521 ASP A C 1 ATOM 3582 O O . ASP A 1 469 ? 35.750 132.439 1.264 1.00 32.45 ? 521 ASP A O 1 ATOM 3583 C CB . ASP A 1 469 ? 34.965 132.336 -1.486 1.00 28.77 ? 521 ASP A CB 1 ATOM 3584 C CG . ASP A 1 469 ? 36.370 132.169 -2.045 1.00 29.41 ? 521 ASP A CG 1 ATOM 3585 O OD1 . ASP A 1 469 ? 37.132 131.322 -1.529 1.00 34.90 ? 521 ASP A OD1 1 ATOM 3586 O OD2 . ASP A 1 469 ? 36.709 132.885 -3.008 1.00 31.70 ? 521 ASP A OD2 1 ATOM 3587 N N . LYS A 1 470 ? 35.944 130.205 1.270 1.00 29.96 ? 522 LYS A N 1 ATOM 3588 C CA . LYS A 1 470 ? 36.710 130.180 2.511 1.00 34.26 ? 522 LYS A CA 1 ATOM 3589 C C . LYS A 1 470 ? 38.213 130.325 2.275 1.00 41.27 ? 522 LYS A C 1 ATOM 3590 O O . LYS A 1 470 ? 39.003 130.201 3.212 1.00 46.24 ? 522 LYS A O 1 ATOM 3591 C CB . LYS A 1 470 ? 36.429 128.885 3.276 1.00 31.59 ? 522 LYS A CB 1 ATOM 3592 C CG . LYS A 1 470 ? 34.987 128.748 3.738 1.00 34.53 ? 522 LYS A CG 1 ATOM 3593 C CD . LYS A 1 470 ? 34.776 127.483 4.545 1.00 38.44 ? 522 LYS A CD 1 ATOM 3594 C CE . LYS A 1 470 ? 33.315 127.317 4.930 1.00 39.93 ? 522 LYS A CE 1 ATOM 3595 N NZ . LYS A 1 470 ? 33.049 125.985 5.534 1.00 50.42 ? 522 LYS A NZ 1 ATOM 3596 N N . CYS A 1 471 ? 38.603 130.600 1.032 1.00 36.38 ? 523 CYS A N 1 ATOM 3597 C CA . CYS A 1 471 ? 40.016 130.706 0.673 1.00 41.21 ? 523 CYS A CA 1 ATOM 3598 C C . CYS A 1 471 ? 40.515 132.151 0.656 1.00 48.54 ? 523 CYS A C 1 ATOM 3599 O O . CYS A 1 471 ? 41.710 132.395 0.482 1.00 56.38 ? 523 CYS A O 1 ATOM 3600 C CB . CYS A 1 471 ? 40.259 130.069 -0.695 1.00 41.78 ? 523 CYS A CB 1 ATOM 3601 S SG . CYS A 1 471 ? 40.099 128.273 -0.706 1.00 54.03 ? 523 CYS A SG 1 ATOM 3602 N N . VAL A 1 472 ? 39.600 133.099 0.840 1.00 42.16 ? 524 VAL A N 1 ATOM 3603 C CA . VAL A 1 472 ? 39.928 134.524 0.776 1.00 50.81 ? 524 VAL A CA 1 ATOM 3604 C C . VAL A 1 472 ? 41.066 134.880 1.730 1.00 50.80 ? 524 VAL A C 1 ATOM 3605 O O . VAL A 1 472 ? 41.903 135.729 1.421 1.00 57.09 ? 524 VAL A O 1 ATOM 3606 C CB . VAL A 1 472 ? 38.707 135.413 1.120 1.00 54.82 ? 524 VAL A CB 1 ATOM 3607 C CG1 . VAL A 1 472 ? 39.008 136.874 0.821 1.00 52.08 ? 524 VAL A CG1 1 ATOM 3608 C CG2 . VAL A 1 472 ? 37.472 134.976 0.345 1.00 46.67 ? 524 VAL A CG2 1 ATOM 3609 N N . ILE B 2 6 ? -6.298 187.274 -5.408 1.00 44.59 ? 1293 ILE C N 1 ATOM 3610 C CA . ILE B 2 6 ? -5.790 186.382 -4.369 1.00 51.87 ? 1293 ILE C CA 1 ATOM 3611 C C . ILE B 2 6 ? -5.589 184.984 -4.933 1.00 40.16 ? 1293 ILE C C 1 ATOM 3612 O O . ILE B 2 6 ? -6.493 184.436 -5.566 1.00 45.32 ? 1293 ILE C O 1 ATOM 3613 C CB . ILE B 2 6 ? -6.748 186.269 -3.163 1.00 54.01 ? 1293 ILE C CB 1 ATOM 3614 C CG1 . ILE B 2 6 ? -7.345 187.628 -2.776 1.00 57.42 ? 1293 ILE C CG1 1 ATOM 3615 C CG2 . ILE B 2 6 ? -6.023 185.646 -1.975 1.00 51.42 ? 1293 ILE C CG2 1 ATOM 3616 C CD1 . ILE B 2 6 ? -8.852 187.583 -2.594 1.00 51.56 ? 1293 ILE C CD1 1 ATOM 3617 N N . VAL B 2 7 ? -4.419 184.398 -4.697 1.00 38.43 ? 1294 VAL C N 1 ATOM 3618 C CA . VAL B 2 7 ? -4.181 183.024 -5.128 1.00 23.63 ? 1294 VAL C CA 1 ATOM 3619 C C . VAL B 2 7 ? -4.743 182.054 -4.096 1.00 23.20 ? 1294 VAL C C 1 ATOM 3620 O O . VAL B 2 7 ? -4.409 182.106 -2.915 1.00 24.24 ? 1294 VAL C O 1 ATOM 3621 C CB . VAL B 2 7 ? -2.686 182.730 -5.350 1.00 31.50 ? 1294 VAL C CB 1 ATOM 3622 C CG1 . VAL B 2 7 ? -2.479 181.268 -5.732 1.00 31.49 ? 1294 VAL C CG1 1 ATOM 3623 C CG2 . VAL B 2 7 ? -2.129 183.639 -6.437 1.00 39.40 ? 1294 VAL C CG2 1 ATOM 3624 N N . GLN B 2 8 ? -5.610 181.168 -4.562 1.00 22.91 ? 1295 GLN C N 1 ATOM 3625 C CA . GLN B 2 8 ? -6.129 180.094 -3.731 1.00 18.25 ? 1295 GLN C CA 1 ATOM 3626 C C . GLN B 2 8 ? -6.559 178.967 -4.644 1.00 19.78 ? 1295 GLN C C 1 ATOM 3627 O O . GLN B 2 8 ? -6.883 179.203 -5.813 1.00 18.63 ? 1295 GLN C O 1 ATOM 3628 C CB . GLN B 2 8 ? -7.297 180.577 -2.869 1.00 24.10 ? 1295 GLN C CB 1 ATOM 3629 C CG . GLN B 2 8 ? -8.530 180.940 -3.664 1.00 23.22 ? 1295 GLN C CG 1 ATOM 3630 C CD . GLN B 2 8 ? -9.567 181.691 -2.845 1.00 27.12 ? 1295 GLN C CD 1 ATOM 3631 O OE1 . GLN B 2 8 ? -10.058 182.739 -3.270 1.00 31.73 ? 1295 GLN C OE1 1 ATOM 3632 N NE2 . GLN B 2 8 ? -9.914 181.157 -1.675 1.00 22.43 ? 1295 GLN C NE2 1 ATOM 3633 N N . ASN B 2 9 ? -6.555 177.740 -4.135 1.00 16.64 ? 1296 ASN C N 1 ATOM 3634 C CA . ASN B 2 9 ? -7.002 176.625 -4.947 1.00 14.95 ? 1296 ASN C CA 1 ATOM 3635 C C . ASN B 2 9 ? -8.514 176.496 -4.875 1.00 16.35 ? 1296 ASN C C 1 ATOM 3636 O O . ASN B 2 9 ? -9.181 177.256 -4.179 1.00 16.69 ? 1296 ASN C O 1 ATOM 3637 C CB . ASN B 2 9 ? -6.309 175.312 -4.546 1.00 15.33 ? 1296 ASN C CB 1 ATOM 3638 C CG . ASN B 2 9 ? -6.660 174.825 -3.143 1.00 16.55 ? 1296 ASN C CG 1 ATOM 3639 O OD1 . ASN B 2 9 ? -7.501 175.384 -2.441 1.00 16.69 ? 1296 ASN C OD1 1 ATOM 3640 N ND2 . ASN B 2 9 ? -5.986 173.752 -2.731 1.00 16.19 ? 1296 ASN C ND2 1 ATOM 3641 N N . GLN B 2 10 ? -9.051 175.548 -5.625 1.00 15.96 ? 1297 GLN C N 1 ATOM 3642 C CA . GLN B 2 10 ? -10.497 175.448 -5.762 1.00 17.53 ? 1297 GLN C CA 1 ATOM 3643 C C . GLN B 2 10 ? -11.169 175.015 -4.466 1.00 18.69 ? 1297 GLN C C 1 ATOM 3644 O O . GLN B 2 10 ? -12.282 175.448 -4.176 1.00 17.91 ? 1297 GLN C O 1 ATOM 3645 C CB . GLN B 2 10 ? -10.858 174.484 -6.892 1.00 18.40 ? 1297 GLN C CB 1 ATOM 3646 C CG . GLN B 2 10 ? -10.493 175.020 -8.263 1.00 22.12 ? 1297 GLN C CG 1 ATOM 3647 C CD . GLN B 2 10 ? -11.295 176.254 -8.646 1.00 29.69 ? 1297 GLN C CD 1 ATOM 3648 O OE1 . GLN B 2 10 ? -12.465 176.391 -8.284 1.00 26.71 ? 1297 GLN C OE1 1 ATOM 3649 N NE2 . GLN B 2 10 ? -10.660 177.164 -9.374 1.00 36.35 ? 1297 GLN C NE2 1 ATOM 3650 N N . SER B 2 11 ? -10.511 174.177 -3.671 1.00 16.17 ? 1298 SER C N 1 ATOM 3651 C CA . SER B 2 11 ? -11.129 173.736 -2.426 1.00 15.58 ? 1298 SER C CA 1 ATOM 3652 C C . SER B 2 11 ? -11.194 174.879 -1.410 1.00 14.66 ? 1298 SER C C 1 ATOM 3653 O O . SER B 2 11 ? -12.104 174.927 -0.579 1.00 17.61 ? 1298 SER C O 1 ATOM 3654 C CB . SER B 2 11 ? -10.384 172.533 -1.853 1.00 16.67 ? 1298 SER C CB 1 ATOM 3655 O OG . SER B 2 11 ? -10.724 171.368 -2.587 1.00 16.25 ? 1298 SER C OG 1 ATOM 3656 N N . SER B 2 12 ? -10.247 175.810 -1.489 1.00 15.30 ? 1299 SER C N 1 ATOM 3657 C CA . SER B 2 12 ? -10.273 177.014 -0.658 1.00 15.33 ? 1299 SER C CA 1 ATOM 3658 C C . SER B 2 12 ? -11.416 177.933 -1.068 1.00 17.49 ? 1299 SER C C 1 ATOM 3659 O O . SER B 2 12 ? -12.122 178.491 -0.222 1.00 18.22 ? 1299 SER C O 1 ATOM 3660 C CB . SER B 2 12 ? -8.934 177.756 -0.755 1.00 14.71 ? 1299 SER C CB 1 ATOM 3661 O OG . SER B 2 12 ? -9.022 179.070 -0.221 1.00 17.28 ? 1299 SER C OG 1 ATOM 3662 N N . LEU B 2 13 ? -11.598 178.083 -2.373 1.00 16.74 ? 1300 LEU C N 1 ATOM 3663 C CA . LEU B 2 13 ? -12.658 178.931 -2.897 1.00 19.48 ? 1300 LEU C CA 1 ATOM 3664 C C . LEU B 2 13 ? -14.041 178.313 -2.664 1.00 18.06 ? 1300 LEU C C 1 ATOM 3665 O O . LEU B 2 13 ? -15.036 179.032 -2.548 1.00 18.71 ? 1300 LEU C O 1 ATOM 3666 C CB . LEU B 2 13 ? -12.433 179.175 -4.390 1.00 21.35 ? 1300 LEU C CB 1 ATOM 3667 C CG . LEU B 2 13 ? -13.486 180.007 -5.120 1.00 29.39 ? 1300 LEU C CG 1 ATOM 3668 C CD1 . LEU B 2 13 ? -13.624 181.378 -4.481 1.00 29.45 ? 1300 LEU C CD1 1 ATOM 3669 C CD2 . LEU B 2 13 ? -13.115 180.124 -6.594 1.00 28.63 ? 1300 LEU C CD2 1 ATOM 3670 N N . ALA B 2 14 ? -14.096 176.987 -2.578 1.00 15.39 ? 1301 ALA C N 1 ATOM 3671 C CA . ALA B 2 14 ? -15.372 176.258 -2.584 1.00 17.83 ? 1301 ALA C CA 1 ATOM 3672 C C . ALA B 2 14 ? -16.418 176.779 -1.578 1.00 18.88 ? 1301 ALA C C 1 ATOM 3673 O O . ALA B 2 14 ? -17.566 176.989 -1.956 1.00 19.24 ? 1301 ALA C O 1 ATOM 3674 C CB . ALA B 2 14 ? -15.128 174.766 -2.352 1.00 17.35 ? 1301 ALA C CB 1 ATOM 3675 N N . PRO B 2 15 ? -16.044 176.984 -0.302 1.00 17.06 ? 1302 PRO C N 1 ATOM 3676 C CA . PRO B 2 15 ? -17.075 177.447 0.643 1.00 16.95 ? 1302 PRO C CA 1 ATOM 3677 C C . PRO B 2 15 ? -17.704 178.787 0.267 1.00 18.94 ? 1302 PRO C C 1 ATOM 3678 O O . PRO B 2 15 ? -18.826 179.069 0.675 1.00 19.41 ? 1302 PRO C O 1 ATOM 3679 C CB . PRO B 2 15 ? -16.319 177.560 1.979 1.00 19.15 ? 1302 PRO C CB 1 ATOM 3680 C CG . PRO B 2 15 ? -14.876 177.382 1.657 1.00 19.85 ? 1302 PRO C CG 1 ATOM 3681 C CD . PRO B 2 15 ? -14.782 176.647 0.375 1.00 16.89 ? 1302 PRO C CD 1 ATOM 3682 N N . GLU B 2 16 ? -16.996 179.592 -0.511 1.00 18.16 ? 1303 GLU C N 1 ATOM 3683 C CA . GLU B 2 16 ? -17.479 180.916 -0.888 1.00 18.41 ? 1303 GLU C CA 1 ATOM 3684 C C . GLU B 2 16 ? -18.426 180.848 -2.093 1.00 22.43 ? 1303 GLU C C 1 ATOM 3685 O O . GLU B 2 16 ? -19.103 181.828 -2.414 1.00 23.70 ? 1303 GLU C O 1 ATOM 3686 C CB . GLU B 2 16 ? -16.292 181.832 -1.190 1.00 20.52 ? 1303 GLU C CB 1 ATOM 3687 C CG . GLU B 2 16 ? -15.156 181.715 -0.164 1.00 21.88 ? 1303 GLU C CG 1 ATOM 3688 C CD . GLU B 2 16 ? -15.640 181.926 1.258 1.00 24.96 ? 1303 GLU C CD 1 ATOM 3689 O OE1 . GLU B 2 16 ? -16.619 182.680 1.446 1.00 25.32 ? 1303 GLU C OE1 1 ATOM 3690 O OE2 . GLU B 2 16 ? -15.050 181.335 2.186 1.00 24.84 ? 1303 GLU C OE2 1 ATOM 3691 N N . LEU B 2 17 ? -18.463 179.689 -2.748 1.00 20.27 ? 1304 LEU C N 1 ATOM 3692 C CA . LEU B 2 17 ? -19.351 179.457 -3.889 1.00 21.64 ? 1304 LEU C CA 1 ATOM 3693 C C . LEU B 2 17 ? -20.547 178.598 -3.505 1.00 23.60 ? 1304 LEU C C 1 ATOM 3694 O O . LEU B 2 17 ? -21.564 178.600 -4.192 1.00 21.70 ? 1304 LEU C O 1 ATOM 3695 C CB . LEU B 2 17 ? -18.596 178.773 -5.036 1.00 19.48 ? 1304 LEU C CB 1 ATOM 3696 C CG . LEU B 2 17 ? -17.366 179.490 -5.588 1.00 20.76 ? 1304 LEU C CG 1 ATOM 3697 C CD1 . LEU B 2 17 ? -16.773 178.703 -6.751 1.00 24.19 ? 1304 LEU C CD1 1 ATOM 3698 C CD2 . LEU B 2 17 ? -17.719 180.902 -6.014 1.00 24.10 ? 1304 LEU C CD2 1 ATOM 3699 N N . SER B 2 18 ? -20.407 177.842 -2.423 1.00 17.63 ? 1305 SER C N 1 ATOM 3700 C CA . SER B 2 18 ? -21.411 176.880 -2.011 1.00 18.24 ? 1305 SER C CA 1 ATOM 3701 C C . SER B 2 18 ? -22.735 177.541 -1.673 1.00 18.90 ? 1305 SER C C 1 ATOM 3702 O O . SER B 2 18 ? -22.770 178.660 -1.166 1.00 19.45 ? 1305 SER C O 1 ATOM 3703 C CB . SER B 2 18 ? -20.916 176.093 -0.797 1.00 19.12 ? 1305 SER C CB 1 ATOM 3704 O OG . SER B 2 18 ? -21.899 175.186 -0.328 1.00 18.96 ? 1305 SER C OG 1 ATOM 3705 N N . GLY B 2 19 ? -23.822 176.837 -1.959 1.00 21.26 ? 1306 GLY C N 1 ATOM 3706 C CA . GLY B 2 19 ? -25.126 177.284 -1.517 1.00 22.28 ? 1306 GLY C CA 1 ATOM 3707 C C . GLY B 2 19 ? -25.302 177.087 -0.020 1.00 24.55 ? 1306 GLY C C 1 ATOM 3708 O O . GLY B 2 19 ? -26.177 177.702 0.586 1.00 22.47 ? 1306 GLY C O 1 ATOM 3709 N N . CYS B 2 20 ? -24.467 176.234 0.575 1.00 20.84 ? 1307 CYS C N 1 ATOM 3710 C CA . CYS B 2 20 ? -24.578 175.891 1.995 1.00 22.75 ? 1307 CYS C CA 1 ATOM 3711 C C . CYS B 2 20 ? -23.242 175.978 2.739 1.00 21.28 ? 1307 CYS C C 1 ATOM 3712 O O . CYS B 2 20 ? -22.746 174.968 3.247 1.00 18.82 ? 1307 CYS C O 1 ATOM 3713 C CB . CYS B 2 20 ? -25.144 174.478 2.149 1.00 23.19 ? 1307 CYS C CB 1 ATOM 3714 S SG . CYS B 2 20 ? -26.847 174.292 1.561 1.00 30.63 ? 1307 CYS C SG 1 ATOM 3715 N N . PRO B 2 21 ? -22.663 177.184 2.817 1.00 21.26 ? 1308 PRO C N 1 ATOM 3716 C CA . PRO B 2 21 ? -21.399 177.355 3.540 1.00 20.34 ? 1308 PRO C CA 1 ATOM 3717 C C . PRO B 2 21 ? -21.583 177.161 5.042 1.00 20.77 ? 1308 PRO C C 1 ATOM 3718 O O . PRO B 2 21 ? -22.705 177.282 5.525 1.00 22.72 ? 1308 PRO C O 1 ATOM 3719 C CB . PRO B 2 21 ? -21.004 178.795 3.221 1.00 20.99 ? 1308 PRO C CB 1 ATOM 3720 C CG . PRO B 2 21 ? -22.314 179.491 2.976 1.00 22.08 ? 1308 PRO C CG 1 ATOM 3721 C CD . PRO B 2 21 ? -23.186 178.464 2.305 1.00 21.72 ? 1308 PRO C CD 1 ATOM 3722 N N . PRO B 2 22 ? -20.489 176.904 5.778 1.00 18.17 ? 1309 PRO C N 1 ATOM 3723 C CA . PRO B 2 22 ? -19.108 176.858 5.286 1.00 19.40 ? 1309 PRO C CA 1 ATOM 3724 C C . PRO B 2 22 ? -18.589 175.471 4.891 1.00 20.59 ? 1309 PRO C C 1 ATOM 3725 O O . PRO B 2 22 ? -17.475 175.403 4.361 1.00 22.31 ? 1309 PRO C O 1 ATOM 3726 C CB . PRO B 2 22 ? -18.316 177.389 6.481 1.00 19.49 ? 1309 PRO C CB 1 ATOM 3727 C CG . PRO B 2 22 ? -19.083 176.910 7.660 1.00 18.90 ? 1309 PRO C CG 1 ATOM 3728 C CD . PRO B 2 22 ? -20.538 176.972 7.250 1.00 19.36 ? 1309 PRO C CD 1 ATOM 3729 N N . MET B 2 23 ? -19.346 174.406 5.149 1.00 18.46 ? 1310 MET C N 1 ATOM 3730 C CA A MET B 2 23 ? -18.885 173.043 4.881 0.40 19.93 ? 1310 MET C CA 1 ATOM 3731 C CA B MET B 2 23 ? -18.867 173.054 4.869 0.60 19.91 ? 1310 MET C CA 1 ATOM 3732 C C . MET B 2 23 ? -19.689 172.323 3.810 1.00 19.98 ? 1310 MET C C 1 ATOM 3733 O O . MET B 2 23 ? -19.274 171.267 3.331 1.00 19.75 ? 1310 MET C O 1 ATOM 3734 C CB A MET B 2 23 ? -18.934 172.197 6.148 0.40 22.29 ? 1310 MET C CB 1 ATOM 3735 C CB B MET B 2 23 ? -18.848 172.231 6.156 0.60 22.24 ? 1310 MET C CB 1 ATOM 3736 C CG A MET B 2 23 ? -17.908 172.551 7.184 0.40 27.74 ? 1310 MET C CG 1 ATOM 3737 C CG B MET B 2 23 ? -17.743 172.634 7.120 0.60 27.67 ? 1310 MET C CG 1 ATOM 3738 S SD A MET B 2 23 ? -17.540 171.097 8.170 0.40 27.92 ? 1310 MET C SD 1 ATOM 3739 S SD B MET B 2 23 ? -16.144 171.905 6.698 0.60 27.92 ? 1310 MET C SD 1 ATOM 3740 C CE A MET B 2 23 ? -16.246 170.349 7.176 0.40 31.13 ? 1310 MET C CE 1 ATOM 3741 C CE B MET B 2 23 ? -16.462 170.184 7.100 0.60 31.58 ? 1310 MET C CE 1 ATOM 3742 N N . GLY B 2 24 ? -20.846 172.876 3.455 1.00 19.51 ? 1311 GLY C N 1 ATOM 3743 C CA . GLY B 2 24 ? -21.698 172.278 2.437 1.00 22.69 ? 1311 GLY C CA 1 ATOM 3744 C C . GLY B 2 24 ? -22.985 171.666 2.975 1.00 22.06 ? 1311 GLY C C 1 ATOM 3745 O O . GLY B 2 24 ? -23.714 171.006 2.236 1.00 24.26 ? 1311 GLY C O 1 ATOM 3746 N N . ILE B 2 25 ? -23.259 171.882 4.259 1.00 23.87 ? 1312 ILE C N 1 ATOM 3747 C CA . ILE B 2 25 ? -24.527 171.481 4.877 1.00 23.55 ? 1312 ILE C CA 1 ATOM 3748 C C . ILE B 2 25 ? -25.256 172.727 5.370 1.00 26.57 ? 1312 ILE C C 1 ATOM 3749 O O . ILE B 2 25 ? -24.724 173.483 6.181 1.00 26.33 ? 1312 ILE C O 1 ATOM 3750 C CB . ILE B 2 25 ? -24.309 170.498 6.053 1.00 22.05 ? 1312 ILE C CB 1 ATOM 3751 C CG1 . ILE B 2 25 ? -23.565 169.250 5.567 1.00 25.17 ? 1312 ILE C CG1 1 ATOM 3752 C CG2 . ILE B 2 25 ? -25.645 170.101 6.680 1.00 25.76 ? 1312 ILE C CG2 1 ATOM 3753 C CD1 . ILE B 2 25 ? -23.210 168.282 6.658 1.00 35.43 ? 1312 ILE C CD1 1 ATOM 3754 N N . CYS B 2 26 ? -26.470 172.954 4.878 1.00 30.88 ? 1313 CYS C N 1 ATOM 3755 C CA . CYS B 2 26 ? -27.200 174.163 5.251 1.00 35.85 ? 1313 CYS C CA 1 ATOM 3756 C C . CYS B 2 26 ? -27.761 174.052 6.672 1.00 40.54 ? 1313 CYS C C 1 ATOM 3757 O O . CYS B 2 26 ? -27.829 172.960 7.244 1.00 32.09 ? 1313 CYS C O 1 ATOM 3758 C CB . CYS B 2 26 ? -28.316 174.448 4.240 1.00 39.61 ? 1313 CYS C CB 1 ATOM 3759 S SG . CYS B 2 26 ? -27.779 175.528 2.874 1.00 45.36 ? 1313 CYS C SG 1 ATOM 3760 N N . MET B 2 27 ? -28.128 175.200 7.237 1.00 40.73 ? 1314 MET C N 1 ATOM 3761 C CA . MET B 2 27 ? -28.668 175.299 8.590 1.00 42.79 ? 1314 MET C CA 1 ATOM 3762 C C . MET B 2 27 ? -29.788 174.279 8.846 1.00 36.26 ? 1314 MET C C 1 ATOM 3763 O O . MET B 2 27 ? -29.959 173.815 9.975 1.00 36.40 ? 1314 MET C O 1 ATOM 3764 C CB . MET B 2 27 ? -29.166 176.735 8.816 1.00 48.31 ? 1314 MET C CB 1 ATOM 3765 C CG . MET B 2 27 ? -29.944 176.981 10.132 1.00 51.74 ? 1314 MET C CG 1 ATOM 3766 S SD . MET B 2 27 ? -31.423 177.962 9.834 1.00 63.25 ? 1314 MET C SD 1 ATOM 3767 C CE . MET B 2 27 ? -30.723 179.529 9.310 1.00 46.03 ? 1314 MET C CE 1 ATOM 3768 N N . ASP B 2 28 ? -30.520 173.905 7.798 1.00 34.50 ? 1315 ASP C N 1 ATOM 3769 C CA . ASP B 2 28 ? -31.638 172.971 7.933 1.00 33.79 ? 1315 ASP C CA 1 ATOM 3770 C C . ASP B 2 28 ? -31.271 171.535 7.542 1.00 45.11 ? 1315 ASP C C 1 ATOM 3771 O O . ASP B 2 28 ? -32.147 170.681 7.395 1.00 32.39 ? 1315 ASP C O 1 ATOM 3772 C CB . ASP B 2 28 ? -32.821 173.453 7.090 1.00 39.15 ? 1315 ASP C CB 1 ATOM 3773 C CG . ASP B 2 28 ? -32.590 173.294 5.601 1.00 47.47 ? 1315 ASP C CG 1 ATOM 3774 O OD1 . ASP B 2 28 ? -31.419 173.298 5.164 1.00 46.37 ? 1315 ASP C OD1 1 ATOM 3775 O OD2 . ASP B 2 28 ? -33.592 173.176 4.863 1.00 50.35 ? 1315 ASP C OD2 1 ATOM 3776 N N . GLY B 2 29 ? -29.978 171.270 7.375 1.00 36.71 ? 1316 GLY C N 1 ATOM 3777 C CA . GLY B 2 29 ? -29.505 169.914 7.152 1.00 37.82 ? 1316 GLY C CA 1 ATOM 3778 C C . GLY B 2 29 ? -29.540 169.463 5.701 1.00 41.54 ? 1316 GLY C C 1 ATOM 3779 O O . GLY B 2 29 ? -29.089 168.362 5.386 1.00 38.58 ? 1316 GLY C O 1 ATOM 3780 N N . THR B 2 30 ? -30.082 170.297 4.817 1.00 42.44 ? 1317 THR C N 1 ATOM 3781 C CA . THR B 2 30 ? -30.047 170.007 3.385 1.00 44.34 ? 1317 THR C CA 1 ATOM 3782 C C . THR B 2 30 ? -28.646 170.323 2.864 1.00 42.12 ? 1317 THR C C 1 ATOM 3783 O O . THR B 2 30 ? -27.858 170.969 3.561 1.00 35.05 ? 1317 THR C O 1 ATOM 3784 C CB . THR B 2 30 ? -31.097 170.822 2.596 1.00 46.83 ? 1317 THR C CB 1 ATOM 3785 O OG1 . THR B 2 30 ? -30.776 172.218 2.652 1.00 46.72 ? 1317 THR C OG1 1 ATOM 3786 C CG2 . THR B 2 30 ? -32.490 170.604 3.164 1.00 47.23 ? 1317 THR C CG2 1 ATOM 3787 N N . ILE B 2 31 ? -28.361 170.003 1.609 1.00 43.01 ? 1318 ILE C N 1 ATOM 3788 C CA . ILE B 2 31 ? -27.073 170.338 0.993 1.00 37.37 ? 1318 ILE C CA 1 ATOM 3789 C C . ILE B 2 31 ? -27.129 171.271 -0.163 1.00 38.52 ? 1318 ILE C C 1 ATOM 3790 O O . ILE B 2 31 ? -28.149 171.560 -0.696 1.00 41.51 ? 1318 ILE C O 1 ATOM 3791 C CB . ILE B 2 31 ? -26.325 169.117 0.422 1.00 31.78 ? 1318 ILE C CB 1 ATOM 3792 C CG1 . ILE B 2 31 ? -27.183 168.408 -0.569 1.00 33.63 ? 1318 ILE C CG1 1 ATOM 3793 C CG2 . ILE B 2 31 ? -25.899 168.178 1.484 1.00 34.76 ? 1318 ILE C CG2 1 ATOM 3794 C CD1 . ILE B 2 31 ? -26.407 167.765 -1.684 1.00 40.20 ? 1318 ILE C CD1 1 ATOM 3795 N N . GLY B 2 32 ? -25.967 171.739 -0.515 1.00 35.48 ? 1319 GLY C N 1 ATOM 3796 C CA . GLY B 2 32 ? -25.596 172.130 -1.838 1.00 39.03 ? 1319 GLY C CA 1 ATOM 3797 C C . GLY B 2 32 ? -26.631 172.269 -2.906 1.00 42.16 ? 1319 GLY C C 1 ATOM 3798 O O . GLY B 2 32 ? -27.442 171.457 -3.146 1.00 47.25 ? 1319 GLY C O 1 ATOM 3799 N N . ASP B 2 33 ? -26.582 173.403 -3.516 1.00 35.35 ? 1320 ASP C N 1 ATOM 3800 C CA . ASP B 2 33 ? -26.045 173.586 -4.789 1.00 33.13 ? 1320 ASP C CA 1 ATOM 3801 C C . ASP B 2 33 ? -24.595 173.834 -4.509 1.00 26.85 ? 1320 ASP C C 1 ATOM 3802 O O . ASP B 2 33 ? -24.275 174.778 -3.854 1.00 27.20 ? 1320 ASP C O 1 ATOM 3803 C CB . ASP B 2 33 ? -26.670 174.769 -5.477 1.00 34.92 ? 1320 ASP C CB 1 ATOM 3804 C CG . ASP B 2 33 ? -26.168 174.969 -6.836 1.00 43.96 ? 1320 ASP C CG 1 ATOM 3805 O OD1 . ASP B 2 33 ? -25.092 174.482 -7.156 1.00 43.76 ? 1320 ASP C OD1 1 ATOM 3806 O OD2 . ASP B 2 33 ? -26.866 175.644 -7.614 1.00 49.74 ? 1320 ASP C OD2 1 ATOM 3807 N N . PRO B 2 34 ? -23.731 172.973 -5.019 1.00 25.02 ? 1321 PRO C N 1 ATOM 3808 C CA . PRO B 2 34 ? -22.316 173.204 -4.712 1.00 22.60 ? 1321 PRO C CA 1 ATOM 3809 C C . PRO B 2 34 ? -21.732 174.470 -5.291 1.00 22.74 ? 1321 PRO C C 1 ATOM 3810 O O . PRO B 2 34 ? -20.874 175.034 -4.687 1.00 21.82 ? 1321 PRO C O 1 ATOM 3811 C CB . PRO B 2 34 ? -21.617 171.971 -5.238 1.00 29.96 ? 1321 PRO C CB 1 ATOM 3812 C CG . PRO B 2 34 ? -22.493 171.415 -6.262 1.00 34.58 ? 1321 PRO C CG 1 ATOM 3813 C CD . PRO B 2 34 ? -23.823 171.612 -5.740 1.00 24.49 ? 1321 PRO C CD 1 ATOM 3814 N N . ILE B 2 35 ? -22.204 174.912 -6.450 1.00 21.00 ? 1322 ILE C N 1 ATOM 3815 C CA . ILE B 2 35 ? -21.764 176.189 -7.001 1.00 19.85 ? 1322 ILE C CA 1 ATOM 3816 C C . ILE B 2 35 ? -22.979 177.074 -7.241 1.00 23.75 ? 1322 ILE C C 1 ATOM 3817 O O . ILE B 2 35 ? -23.638 176.986 -8.279 1.00 25.22 ? 1322 ILE C O 1 ATOM 3818 C CB . ILE B 2 35 ? -20.959 176.003 -8.300 1.00 21.27 ? 1322 ILE C CB 1 ATOM 3819 C CG1 . ILE B 2 35 ? -19.732 175.123 -8.021 1.00 25.46 ? 1322 ILE C CG1 1 ATOM 3820 C CG2 . ILE B 2 35 ? -20.530 177.358 -8.859 1.00 23.52 ? 1322 ILE C CG2 1 ATOM 3821 C CD1 . ILE B 2 35 ? -18.875 174.820 -9.248 1.00 28.19 ? 1322 ILE C CD1 1 ATOM 3822 N N . ALA B 2 36 ? -23.256 177.935 -6.267 1.00 21.54 ? 1323 ALA C N 1 ATOM 3823 C CA . ALA B 2 36 ? -24.492 178.710 -6.248 1.00 19.92 ? 1323 ALA C CA 1 ATOM 3824 C C . ALA B 2 36 ? -24.300 180.152 -6.711 1.00 25.39 ? 1323 ALA C C 1 ATOM 3825 O O . ALA B 2 36 ? -25.259 180.915 -6.773 1.00 25.95 ? 1323 ALA C O 1 ATOM 3826 C CB . ALA B 2 36 ? -25.089 178.690 -4.851 1.00 21.43 ? 1323 ALA C CB 1 ATOM 3827 N N . SER B 2 37 ? -23.069 180.528 -7.036 1.00 26.15 ? 1324 SER C N 1 ATOM 3828 C CA . SER B 2 37 ? -22.793 181.875 -7.517 1.00 31.08 ? 1324 SER C CA 1 ATOM 3829 C C . SER B 2 37 ? -21.573 181.862 -8.421 1.00 34.65 ? 1324 SER C C 1 ATOM 3830 O O . SER B 2 37 ? -20.890 180.843 -8.520 1.00 33.64 ? 1324 SER C O 1 ATOM 3831 C CB . SER B 2 37 ? -22.578 182.837 -6.346 1.00 33.76 ? 1324 SER C CB 1 ATOM 3832 O OG . SER B 2 37 ? -21.431 182.477 -5.596 1.00 37.91 ? 1324 SER C OG 1 ATOM 3833 O OXT . SER B 2 37 ? -21.254 182.858 -9.074 1.00 37.78 ? 1324 SER C OXT 1 ATOM 3834 N N . SER C 1 7 ? 17.542 122.989 20.911 1.00 43.85 ? 59 SER B N 1 ATOM 3835 C CA . SER C 1 7 ? 16.813 124.192 20.519 1.00 34.08 ? 59 SER B CA 1 ATOM 3836 C C . SER C 1 7 ? 16.426 124.129 19.043 1.00 31.16 ? 59 SER B C 1 ATOM 3837 O O . SER C 1 7 ? 15.241 124.195 18.704 1.00 25.63 ? 59 SER B O 1 ATOM 3838 C CB . SER C 1 7 ? 17.652 125.443 20.793 1.00 44.43 ? 59 SER B CB 1 ATOM 3839 O OG . SER C 1 7 ? 16.876 126.621 20.646 1.00 43.23 ? 59 SER B OG 1 ATOM 3840 N N . THR C 1 8 ? 17.425 123.997 18.172 1.00 30.30 ? 60 THR B N 1 ATOM 3841 C CA . THR C 1 8 ? 17.175 123.915 16.737 1.00 21.23 ? 60 THR B CA 1 ATOM 3842 C C . THR C 1 8 ? 16.419 122.644 16.373 1.00 23.96 ? 60 THR B C 1 ATOM 3843 O O . THR C 1 8 ? 15.521 122.684 15.539 1.00 19.51 ? 60 THR B O 1 ATOM 3844 C CB . THR C 1 8 ? 18.476 123.960 15.922 1.00 28.96 ? 60 THR B CB 1 ATOM 3845 O OG1 . THR C 1 8 ? 19.444 123.090 16.519 1.00 37.16 ? 60 THR B OG1 1 ATOM 3846 C CG2 . THR C 1 8 ? 19.030 125.377 15.874 1.00 26.24 ? 60 THR B CG2 1 ATOM 3847 N N . SER C 1 9 ? 16.779 121.519 16.987 1.00 23.19 ? 61 SER B N 1 ATOM 3848 C CA . SER C 1 9 ? 16.075 120.267 16.712 1.00 20.92 ? 61 SER B CA 1 ATOM 3849 C C . SER C 1 9 ? 14.603 120.352 17.131 1.00 19.94 ? 61 SER B C 1 ATOM 3850 O O . SER C 1 9 ? 13.718 119.856 16.431 1.00 18.58 ? 61 SER B O 1 ATOM 3851 C CB . SER C 1 9 ? 16.762 119.093 17.418 1.00 24.04 ? 61 SER B CB 1 ATOM 3852 O OG . SER C 1 9 ? 16.700 119.230 18.825 1.00 32.18 ? 61 SER B OG 1 ATOM 3853 N N . THR C 1 10 ? 14.335 120.987 18.265 1.00 19.90 ? 62 THR B N 1 ATOM 3854 C CA . THR C 1 10 ? 12.963 121.167 18.730 1.00 18.85 ? 62 THR B CA 1 ATOM 3855 C C . THR C 1 10 ? 12.188 122.097 17.795 1.00 18.58 ? 62 THR B C 1 ATOM 3856 O O . THR C 1 10 ? 11.057 121.804 17.406 1.00 17.18 ? 62 THR B O 1 ATOM 3857 C CB . THR C 1 10 ? 12.949 121.720 20.170 1.00 25.27 ? 62 THR B CB 1 ATOM 3858 O OG1 . THR C 1 10 ? 13.647 120.804 21.023 1.00 29.82 ? 62 THR B OG1 1 ATOM 3859 C CG2 . THR C 1 10 ? 11.527 121.898 20.687 1.00 27.38 ? 62 THR B CG2 1 ATOM 3860 N N . SER C 1 11 ? 12.800 123.216 17.423 1.00 17.65 ? 63 SER B N 1 ATOM 3861 C CA . SER C 1 11 ? 12.180 124.147 16.492 1.00 17.78 ? 63 SER B CA 1 ATOM 3862 C C . SER C 1 11 ? 11.927 123.509 15.132 1.00 16.48 ? 63 SER B C 1 ATOM 3863 O O . SER C 1 11 ? 10.898 123.762 14.499 1.00 14.30 ? 63 SER B O 1 ATOM 3864 C CB . SER C 1 11 ? 13.060 125.382 16.332 1.00 17.36 ? 63 SER B CB 1 ATOM 3865 O OG . SER C 1 11 ? 13.016 126.151 17.517 1.00 22.44 ? 63 SER B OG 1 ATOM 3866 N N . ARG C 1 12 ? 12.854 122.669 14.694 1.00 15.38 ? 64 ARG B N 1 ATOM 3867 C CA . ARG C 1 12 ? 12.688 121.961 13.433 1.00 14.65 ? 64 ARG B CA 1 ATOM 3868 C C . ARG C 1 12 ? 11.482 121.035 13.501 1.00 15.22 ? 64 ARG B C 1 ATOM 3869 O O . ARG C 1 12 ? 10.668 121.002 12.575 1.00 14.65 ? 64 ARG B O 1 ATOM 3870 C CB . ARG C 1 12 ? 13.939 121.171 13.092 1.00 14.87 ? 64 ARG B CB 1 ATOM 3871 C CG . ARG C 1 12 ? 13.817 120.388 11.787 1.00 15.78 ? 64 ARG B CG 1 ATOM 3872 C CD . ARG C 1 12 ? 15.142 119.805 11.345 1.00 19.98 ? 64 ARG B CD 1 ATOM 3873 N NE . ARG C 1 12 ? 16.172 120.840 11.358 1.00 26.74 ? 64 ARG B NE 1 ATOM 3874 C CZ . ARG C 1 12 ? 17.140 120.941 12.265 1.00 30.28 ? 64 ARG B CZ 1 ATOM 3875 N NH1 . ARG C 1 12 ? 17.262 120.048 13.241 1.00 28.35 ? 64 ARG B NH1 1 ATOM 3876 N NH2 . ARG C 1 12 ? 18.004 121.942 12.185 1.00 34.52 ? 64 ARG B NH2 1 ATOM 3877 N N . ALA C 1 13 ? 11.367 120.281 14.590 1.00 15.86 ? 65 ALA B N 1 ATOM 3878 C CA . ALA C 1 13 ? 10.230 119.375 14.750 1.00 16.59 ? 65 ALA B CA 1 ATOM 3879 C C . ALA C 1 13 ? 8.904 120.135 14.777 1.00 16.64 ? 65 ALA B C 1 ATOM 3880 O O . ALA C 1 13 ? 7.919 119.705 14.180 1.00 16.20 ? 65 ALA B O 1 ATOM 3881 C CB . ALA C 1 13 ? 10.381 118.541 16.010 1.00 16.85 ? 65 ALA B CB 1 ATOM 3882 N N . THR C 1 14 ? 8.871 121.271 15.460 1.00 14.93 ? 66 THR B N 1 ATOM 3883 C CA . THR C 1 14 ? 7.651 122.057 15.536 1.00 15.24 ? 66 THR B CA 1 ATOM 3884 C C . THR C 1 14 ? 7.250 122.555 14.152 1.00 13.66 ? 66 THR B C 1 ATOM 3885 O O . THR C 1 14 ? 6.074 122.530 13.802 1.00 17.49 ? 66 THR B O 1 ATOM 3886 C CB . THR C 1 14 ? 7.828 123.237 16.494 1.00 20.31 ? 66 THR B CB 1 ATOM 3887 O OG1 . THR C 1 14 ? 8.069 122.724 17.808 1.00 19.41 ? 66 THR B OG1 1 ATOM 3888 C CG2 . THR C 1 14 ? 6.593 124.107 16.523 1.00 21.00 ? 66 THR B CG2 1 ATOM 3889 N N . TYR C 1 15 ? 8.228 122.982 13.364 1.00 12.98 ? 67 TYR B N 1 ATOM 3890 C CA . TYR C 1 15 ? 7.947 123.447 12.011 1.00 13.92 ? 67 TYR B CA 1 ATOM 3891 C C . TYR C 1 15 ? 7.469 122.298 11.125 1.00 13.25 ? 67 TYR B C 1 ATOM 3892 O O . TYR C 1 15 ? 6.462 122.426 10.424 1.00 14.06 ? 67 TYR B O 1 ATOM 3893 C CB . TYR C 1 15 ? 9.179 124.107 11.386 1.00 14.24 ? 67 TYR B CB 1 ATOM 3894 C CG . TYR C 1 15 ? 9.003 124.405 9.916 1.00 15.02 ? 67 TYR B CG 1 ATOM 3895 C CD1 . TYR C 1 15 ? 8.208 125.457 9.484 1.00 16.41 ? 67 TYR B CD1 1 ATOM 3896 C CD2 . TYR C 1 15 ? 9.627 123.618 8.956 1.00 13.43 ? 67 TYR B CD2 1 ATOM 3897 C CE1 . TYR C 1 15 ? 8.040 125.713 8.124 1.00 15.23 ? 67 TYR B CE1 1 ATOM 3898 C CE2 . TYR C 1 15 ? 9.468 123.865 7.614 1.00 15.23 ? 67 TYR B CE2 1 ATOM 3899 C CZ . TYR C 1 15 ? 8.679 124.906 7.197 1.00 13.52 ? 67 TYR B CZ 1 ATOM 3900 O OH . TYR C 1 15 ? 8.555 125.123 5.839 1.00 18.16 ? 67 TYR B OH 1 ATOM 3901 N N . MET C 1 16 ? 8.188 121.181 11.165 1.00 12.77 ? 68 MET B N 1 ATOM 3902 C CA . MET C 1 16 ? 7.899 120.058 10.270 1.00 12.43 ? 68 MET B CA 1 ATOM 3903 C C . MET C 1 16 ? 6.563 119.373 10.594 1.00 12.29 ? 68 MET B C 1 ATOM 3904 O O . MET C 1 16 ? 6.039 118.634 9.767 1.00 12.84 ? 68 MET B O 1 ATOM 3905 C CB . MET C 1 16 ? 9.048 119.041 10.308 1.00 12.56 ? 68 MET B CB 1 ATOM 3906 C CG . MET C 1 16 ? 10.321 119.535 9.613 1.00 13.55 ? 68 MET B CG 1 ATOM 3907 S SD . MET C 1 16 ? 10.102 119.893 7.858 1.00 14.77 ? 68 MET B SD 1 ATOM 3908 C CE . MET C 1 16 ? 9.765 118.256 7.193 1.00 11.84 ? 68 MET B CE 1 ATOM 3909 N N . ASP C 1 17 ? 6.009 119.633 11.775 1.00 13.42 ? 69 ASP B N 1 ATOM 3910 C CA . ASP C 1 17 ? 4.684 119.148 12.161 1.00 13.43 ? 69 ASP B CA 1 ATOM 3911 C C . ASP C 1 17 ? 3.625 119.499 11.114 1.00 11.37 ? 69 ASP B C 1 ATOM 3912 O O . ASP C 1 17 ? 2.677 118.749 10.913 1.00 12.95 ? 69 ASP B O 1 ATOM 3913 C CB . ASP C 1 17 ? 4.314 119.745 13.526 1.00 15.80 ? 69 ASP B CB 1 ATOM 3914 C CG . ASP C 1 17 ? 3.017 119.195 14.105 1.00 18.51 ? 69 ASP B CG 1 ATOM 3915 O OD1 . ASP C 1 17 ? 2.713 117.996 13.929 1.00 20.40 ? 69 ASP B OD1 1 ATOM 3916 O OD2 . ASP C 1 17 ? 2.318 119.966 14.793 1.00 21.94 ? 69 ASP B OD2 1 ATOM 3917 N N . ARG C 1 18 ? 3.793 120.631 10.428 1.00 12.87 ? 70 ARG B N 1 ATOM 3918 C CA . ARG C 1 18 ? 2.773 121.096 9.492 1.00 10.74 ? 70 ARG B CA 1 ATOM 3919 C C . ARG C 1 18 ? 2.671 120.172 8.275 1.00 12.16 ? 70 ARG B C 1 ATOM 3920 O O . ARG C 1 18 ? 1.713 120.279 7.504 1.00 12.09 ? 70 ARG B O 1 ATOM 3921 C CB . ARG C 1 18 ? 3.051 122.547 9.043 1.00 12.70 ? 70 ARG B CB 1 ATOM 3922 C CG . ARG C 1 18 ? 4.227 122.725 8.081 1.00 13.21 ? 70 ARG B CG 1 ATOM 3923 C CD . ARG C 1 18 ? 4.601 124.203 7.929 1.00 15.83 ? 70 ARG B CD 1 ATOM 3924 N NE . ARG C 1 18 ? 4.828 124.803 9.243 1.00 13.08 ? 70 ARG B NE 1 ATOM 3925 C CZ . ARG C 1 18 ? 4.775 126.106 9.499 1.00 15.91 ? 70 ARG B CZ 1 ATOM 3926 N NH1 . ARG C 1 18 ? 4.528 126.977 8.524 1.00 15.93 ? 70 ARG B NH1 1 ATOM 3927 N NH2 . ARG C 1 18 ? 4.976 126.540 10.735 1.00 17.52 ? 70 ARG B NH2 1 ATOM 3928 N N . PHE C 1 19 ? 3.646 119.277 8.110 1.00 12.19 ? 71 PHE B N 1 ATOM 3929 C CA . PHE C 1 19 ? 3.638 118.330 6.990 1.00 10.55 ? 71 PHE B CA 1 ATOM 3930 C C . PHE C 1 19 ? 3.195 116.936 7.412 1.00 15.05 ? 71 PHE B C 1 ATOM 3931 O O . PHE C 1 19 ? 3.176 116.028 6.581 1.00 12.00 ? 71 PHE B O 1 ATOM 3932 C CB . PHE C 1 19 ? 5.019 118.260 6.333 1.00 14.02 ? 71 PHE B CB 1 ATOM 3933 C CG . PHE C 1 19 ? 5.502 119.589 5.824 1.00 11.39 ? 71 PHE B CG 1 ATOM 3934 C CD1 . PHE C 1 19 ? 4.868 120.200 4.747 1.00 12.90 ? 71 PHE B CD1 1 ATOM 3935 C CD2 . PHE C 1 19 ? 6.564 120.238 6.424 1.00 13.80 ? 71 PHE B CD2 1 ATOM 3936 C CE1 . PHE C 1 19 ? 5.287 121.430 4.275 1.00 14.97 ? 71 PHE B CE1 1 ATOM 3937 C CE2 . PHE C 1 19 ? 6.989 121.468 5.956 1.00 13.43 ? 71 PHE B CE2 1 ATOM 3938 C CZ . PHE C 1 19 ? 6.344 122.066 4.881 1.00 13.09 ? 71 PHE B CZ 1 ATOM 3939 N N . ASN C 1 20 ? 2.806 116.763 8.674 1.00 10.98 ? 72 ASN B N 1 ATOM 3940 C CA . ASN C 1 20 ? 2.362 115.452 9.138 1.00 11.38 ? 72 ASN B CA 1 ATOM 3941 C C . ASN C 1 20 ? 0.879 115.278 8.858 1.00 11.71 ? 72 ASN B C 1 ATOM 3942 O O . ASN C 1 20 ? 0.028 115.387 9.743 1.00 12.16 ? 72 ASN B O 1 ATOM 3943 C CB . ASN C 1 20 ? 2.646 115.257 10.617 1.00 13.01 ? 72 ASN B CB 1 ATOM 3944 C CG . ASN C 1 20 ? 2.466 113.821 11.047 1.00 13.47 ? 72 ASN B CG 1 ATOM 3945 O OD1 . ASN C 1 20 ? 1.887 113.009 10.319 1.00 13.42 ? 72 ASN B OD1 1 ATOM 3946 N ND2 . ASN C 1 20 ? 2.948 113.498 12.228 1.00 14.72 ? 72 ASN B ND2 1 ATOM 3947 N N . ILE C 1 21 ? 0.580 115.009 7.594 1.00 12.34 ? 73 ILE B N 1 ATOM 3948 C CA . ILE C 1 21 ? -0.792 115.016 7.117 1.00 11.96 ? 73 ILE B CA 1 ATOM 3949 C C . ILE C 1 21 ? -1.689 113.970 7.808 1.00 11.72 ? 73 ILE B C 1 ATOM 3950 O O . ILE C 1 21 ? -2.794 114.313 8.214 1.00 11.97 ? 73 ILE B O 1 ATOM 3951 C CB . ILE C 1 21 ? -0.799 114.856 5.581 1.00 12.20 ? 73 ILE B CB 1 ATOM 3952 C CG1 . ILE C 1 21 ? -0.263 116.154 4.949 1.00 12.70 ? 73 ILE B CG1 1 ATOM 3953 C CG2 . ILE C 1 21 ? -2.193 114.531 5.057 1.00 11.32 ? 73 ILE B CG2 1 ATOM 3954 C CD1 . ILE C 1 21 ? 0.013 116.096 3.460 1.00 13.34 ? 73 ILE B CD1 1 ATOM 3955 N N . PRO C 1 22 ? -1.228 112.709 7.970 1.00 10.19 ? 74 PRO B N 1 ATOM 3956 C CA . PRO C 1 22 ? -2.162 111.785 8.633 1.00 12.47 ? 74 PRO B CA 1 ATOM 3957 C C . PRO C 1 22 ? -2.504 112.175 10.081 1.00 11.88 ? 74 PRO B C 1 ATOM 3958 O O . PRO C 1 22 ? -3.629 111.952 10.528 1.00 13.86 ? 74 PRO B O 1 ATOM 3959 C CB . PRO C 1 22 ? -1.420 110.443 8.583 1.00 13.43 ? 74 PRO B CB 1 ATOM 3960 C CG . PRO C 1 22 ? -0.532 110.561 7.364 1.00 12.89 ? 74 PRO B CG 1 ATOM 3961 C CD . PRO C 1 22 ? -0.072 112.004 7.390 1.00 11.44 ? 74 PRO B CD 1 ATOM 3962 N N . LYS C 1 23 ? -1.556 112.778 10.788 1.00 12.35 ? 75 LYS B N 1 ATOM 3963 C CA . LYS C 1 23 ? -1.784 113.179 12.170 1.00 12.74 ? 75 LYS B CA 1 ATOM 3964 C C . LYS C 1 23 ? -2.681 114.410 12.274 1.00 11.61 ? 75 LYS B C 1 ATOM 3965 O O . LYS C 1 23 ? -3.482 114.524 13.206 1.00 14.78 ? 75 LYS B O 1 ATOM 3966 C CB . LYS C 1 23 ? -0.443 113.453 12.869 1.00 12.72 ? 75 LYS B CB 1 ATOM 3967 C CG . LYS C 1 23 ? -0.554 113.669 14.376 1.00 18.38 ? 75 LYS B CG 1 ATOM 3968 C CD . LYS C 1 23 ? 0.823 113.856 14.992 1.00 20.35 ? 75 LYS B CD 1 ATOM 3969 C CE . LYS C 1 23 ? 0.759 113.851 16.519 1.00 25.15 ? 75 LYS B CE 1 ATOM 3970 N NZ . LYS C 1 23 ? 0.083 115.060 17.073 1.00 27.66 ? 75 LYS B NZ 1 ATOM 3971 N N . ASN C 1 24 ? -2.551 115.331 11.322 1.00 12.32 ? 76 ASN B N 1 ATOM 3972 C CA . ASN C 1 24 ? -3.182 116.647 11.462 1.00 11.65 ? 76 ASN B CA 1 ATOM 3973 C C . ASN C 1 24 ? -4.391 116.906 10.559 1.00 13.72 ? 76 ASN B C 1 ATOM 3974 O O . ASN C 1 24 ? -5.212 117.765 10.869 1.00 12.10 ? 76 ASN B O 1 ATOM 3975 C CB . ASN C 1 24 ? -2.122 117.721 11.252 1.00 12.98 ? 76 ASN B CB 1 ATOM 3976 C CG . ASN C 1 24 ? -1.049 117.664 12.318 1.00 14.25 ? 76 ASN B CG 1 ATOM 3977 O OD1 . ASN C 1 24 ? -1.283 117.114 13.398 1.00 16.34 ? 76 ASN B OD1 1 ATOM 3978 N ND2 . ASN C 1 24 ? 0.121 118.206 12.030 1.00 15.08 ? 76 ASN B ND2 1 ATOM 3979 N N . HIS C 1 25 ? -4.524 116.151 9.474 1.00 11.50 ? 77 HIS B N 1 ATOM 3980 C CA . HIS C 1 25 ? -5.713 116.231 8.633 1.00 12.04 ? 77 HIS B CA 1 ATOM 3981 C C . HIS C 1 25 ? -6.809 115.375 9.268 1.00 13.94 ? 77 HIS B C 1 ATOM 3982 O O . HIS C 1 25 ? -7.076 114.239 8.849 1.00 13.49 ? 77 HIS B O 1 ATOM 3983 C CB . HIS C 1 25 ? -5.389 115.774 7.204 1.00 11.71 ? 77 HIS B CB 1 ATOM 3984 C CG . HIS C 1 25 ? -6.455 116.099 6.207 1.00 11.79 ? 77 HIS B CG 1 ATOM 3985 N ND1 . HIS C 1 25 ? -6.899 117.387 5.987 1.00 11.88 ? 77 HIS B ND1 1 ATOM 3986 C CD2 . HIS C 1 25 ? -7.151 115.307 5.357 1.00 11.10 ? 77 HIS B CD2 1 ATOM 3987 C CE1 . HIS C 1 25 ? -7.828 117.371 5.047 1.00 11.26 ? 77 HIS B CE1 1 ATOM 3988 N NE2 . HIS C 1 25 ? -8.002 116.121 4.651 1.00 12.95 ? 77 HIS B NE2 1 ATOM 3989 N N . VAL C 1 26 ? -7.436 115.932 10.301 1.00 13.03 ? 78 VAL B N 1 ATOM 3990 C CA . VAL C 1 26 ? -8.311 115.172 11.177 1.00 12.28 ? 78 VAL B CA 1 ATOM 3991 C C . VAL C 1 26 ? -9.786 115.472 10.931 1.00 13.20 ? 78 VAL B C 1 ATOM 3992 O O . VAL C 1 26 ? -10.149 116.396 10.190 1.00 14.11 ? 78 VAL B O 1 ATOM 3993 C CB . VAL C 1 26 ? -7.973 115.443 12.672 1.00 13.09 ? 78 VAL B CB 1 ATOM 3994 C CG1 . VAL C 1 26 ? -6.500 115.171 12.937 1.00 16.93 ? 78 VAL B CG1 1 ATOM 3995 C CG2 . VAL C 1 26 ? -8.328 116.873 13.078 1.00 15.75 ? 78 VAL B CG2 1 ATOM 3996 N N . ASP C 1 27 ? -10.626 114.647 11.543 1.00 12.68 ? 79 ASP B N 1 ATOM 3997 C CA . ASP C 1 27 ? -12.060 114.868 11.576 1.00 13.25 ? 79 ASP B CA 1 ATOM 3998 C C . ASP C 1 27 ? -12.405 115.442 12.933 1.00 17.02 ? 79 ASP B C 1 ATOM 3999 O O . ASP C 1 27 ? -12.285 114.749 13.942 1.00 16.67 ? 79 ASP B O 1 ATOM 4000 C CB . ASP C 1 27 ? -12.814 113.568 11.338 1.00 14.70 ? 79 ASP B CB 1 ATOM 4001 C CG . ASP C 1 27 ? -14.315 113.757 11.361 1.00 17.01 ? 79 ASP B CG 1 ATOM 4002 O OD1 . ASP C 1 27 ? -14.805 114.665 10.661 1.00 19.30 ? 79 ASP B OD1 1 ATOM 4003 O OD2 . ASP C 1 27 ? -14.996 112.988 12.068 1.00 19.87 ? 79 ASP B OD2 1 ATOM 4004 N N . LEU C 1 28 ? -12.808 116.705 12.966 1.00 16.66 ? 80 LEU B N 1 ATOM 4005 C CA . LEU C 1 28 ? -13.185 117.333 14.224 1.00 15.97 ? 80 LEU B CA 1 ATOM 4006 C C . LEU C 1 28 ? -14.623 117.828 14.183 1.00 19.42 ? 80 LEU B C 1 ATOM 4007 O O . LEU C 1 28 ? -15.190 118.039 13.114 1.00 17.16 ? 80 LEU B O 1 ATOM 4008 C CB . LEU C 1 28 ? -12.229 118.481 14.553 1.00 16.81 ? 80 LEU B CB 1 ATOM 4009 C CG . LEU C 1 28 ? -12.207 119.707 13.635 1.00 16.22 ? 80 LEU B CG 1 ATOM 4010 C CD1 . LEU C 1 28 ? -13.291 120.711 14.016 1.00 18.19 ? 80 LEU B CD1 1 ATOM 4011 C CD2 . LEU C 1 28 ? -10.850 120.376 13.677 1.00 17.13 ? 80 LEU B CD2 1 ATOM 4012 N N . ILE C 1 29 ? -15.216 117.977 15.361 1.00 17.84 ? 81 ILE B N 1 ATOM 4013 C CA . ILE C 1 29 ? -16.526 118.603 15.491 1.00 16.29 ? 81 ILE B CA 1 ATOM 4014 C C . ILE C 1 29 ? -16.384 119.722 16.518 1.00 19.92 ? 81 ILE B C 1 ATOM 4015 O O . ILE C 1 29 ? -15.512 119.666 17.388 1.00 18.12 ? 81 ILE B O 1 ATOM 4016 C CB . ILE C 1 29 ? -17.619 117.589 15.899 1.00 18.79 ? 81 ILE B CB 1 ATOM 4017 C CG1 . ILE C 1 29 ? -17.239 116.839 17.181 1.00 27.83 ? 81 ILE B CG1 1 ATOM 4018 C CG2 . ILE C 1 29 ? -17.847 116.595 14.777 1.00 19.83 ? 81 ILE B CG2 1 ATOM 4019 C CD1 . ILE C 1 29 ? -17.950 117.338 18.418 1.00 25.40 ? 81 ILE B CD1 1 ATOM 4020 N N . TRP C 1 30 ? -17.205 120.760 16.396 1.00 19.33 ? 82 TRP B N 1 ATOM 4021 C CA . TRP C 1 30 ? -17.121 121.887 17.316 1.00 20.50 ? 82 TRP B CA 1 ATOM 4022 C C . TRP C 1 30 ? -17.935 121.577 18.569 1.00 16.97 ? 82 TRP B C 1 ATOM 4023 O O . TRP C 1 30 ? -19.056 121.085 18.491 1.00 21.00 ? 82 TRP B O 1 ATOM 4024 C CB . TRP C 1 30 ? -17.619 123.183 16.656 1.00 18.00 ? 82 TRP B CB 1 ATOM 4025 C CG . TRP C 1 30 ? -16.969 123.485 15.323 1.00 16.10 ? 82 TRP B CG 1 ATOM 4026 C CD1 . TRP C 1 30 ? -17.571 123.454 14.096 1.00 16.93 ? 82 TRP B CD1 1 ATOM 4027 C CD2 . TRP C 1 30 ? -15.606 123.859 15.090 1.00 16.78 ? 82 TRP B CD2 1 ATOM 4028 N NE1 . TRP C 1 30 ? -16.669 123.783 13.119 1.00 16.31 ? 82 TRP B NE1 1 ATOM 4029 C CE2 . TRP C 1 30 ? -15.454 124.035 13.698 1.00 16.19 ? 82 TRP B CE2 1 ATOM 4030 C CE3 . TRP C 1 30 ? -14.496 124.051 15.917 1.00 17.36 ? 82 TRP B CE3 1 ATOM 4031 C CZ2 . TRP C 1 30 ? -14.240 124.392 13.119 1.00 16.04 ? 82 TRP B CZ2 1 ATOM 4032 C CZ3 . TRP C 1 30 ? -13.290 124.415 15.338 1.00 17.80 ? 82 TRP B CZ3 1 ATOM 4033 C CH2 . TRP C 1 30 ? -13.171 124.578 13.950 1.00 16.86 ? 82 TRP B CH2 1 ATOM 4034 N N . ASP C 1 31 ? -17.350 121.842 19.729 1.00 26.46 ? 83 ASP B N 1 ATOM 4035 C CA . ASP C 1 31 ? -18.054 121.654 20.992 1.00 28.21 ? 83 ASP B CA 1 ATOM 4036 C C . ASP C 1 31 ? -17.330 122.444 22.070 1.00 25.95 ? 83 ASP B C 1 ATOM 4037 O O . ASP C 1 31 ? -16.106 122.416 22.137 1.00 26.89 ? 83 ASP B O 1 ATOM 4038 C CB . ASP C 1 31 ? -18.133 120.170 21.363 1.00 31.63 ? 83 ASP B CB 1 ATOM 4039 C CG . ASP C 1 31 ? -19.171 119.891 22.436 1.00 30.73 ? 83 ASP B CG 1 ATOM 4040 O OD1 . ASP C 1 31 ? -18.876 120.125 23.626 1.00 39.43 ? 83 ASP B OD1 1 ATOM 4041 O OD2 . ASP C 1 31 ? -20.283 119.438 22.090 1.00 34.39 ? 83 ASP B OD2 1 ATOM 4042 N N . LYS C 1 32 ? -18.077 123.161 22.904 1.00 33.13 ? 84 LYS B N 1 ATOM 4043 C CA . LYS C 1 32 ? -17.455 124.009 23.916 1.00 31.69 ? 84 LYS B CA 1 ATOM 4044 C C . LYS C 1 32 ? -16.732 123.184 24.981 1.00 27.60 ? 84 LYS B C 1 ATOM 4045 O O . LYS C 1 32 ? -15.873 123.702 25.687 1.00 32.37 ? 84 LYS B O 1 ATOM 4046 C CB . LYS C 1 32 ? -18.496 124.924 24.576 1.00 32.46 ? 84 LYS B CB 1 ATOM 4047 C CG . LYS C 1 32 ? -19.554 124.221 25.401 1.00 36.00 ? 84 LYS B CG 1 ATOM 4048 C CD . LYS C 1 32 ? -20.265 125.221 26.301 1.00 43.89 ? 84 LYS B CD 1 ATOM 4049 C CE . LYS C 1 32 ? -21.688 124.792 26.608 1.00 50.22 ? 84 LYS B CE 1 ATOM 4050 N NZ . LYS C 1 32 ? -21.770 123.412 27.158 1.00 55.36 ? 84 LYS B NZ 1 ATOM 4051 N N . ASP C 1 33 ? -17.074 121.902 25.081 1.00 31.14 ? 85 ASP B N 1 ATOM 4052 C CA . ASP C 1 33 ? -16.432 121.001 26.037 1.00 31.75 ? 85 ASP B CA 1 ATOM 4053 C C . ASP C 1 33 ? -15.345 120.157 25.370 1.00 38.80 ? 85 ASP B C 1 ATOM 4054 O O . ASP C 1 33 ? -14.781 119.252 25.988 1.00 39.00 ? 85 ASP B O 1 ATOM 4055 C CB . ASP C 1 33 ? -17.476 120.095 26.690 1.00 35.23 ? 85 ASP B CB 1 ATOM 4056 C CG . ASP C 1 33 ? -18.525 120.879 27.460 1.00 39.98 ? 85 ASP B CG 1 ATOM 4057 O OD1 . ASP C 1 33 ? -18.147 121.835 28.167 1.00 38.50 ? 85 ASP B OD1 1 ATOM 4058 O OD2 . ASP C 1 33 ? -19.725 120.547 27.351 1.00 47.03 ? 85 ASP B OD2 1 ATOM 4059 N N . GLY C 1 34 ? -15.049 120.458 24.109 1.00 34.16 ? 86 GLY B N 1 ATOM 4060 C CA . GLY C 1 34 ? -14.008 119.749 23.386 1.00 35.26 ? 86 GLY B CA 1 ATOM 4061 C C . GLY C 1 34 ? -12.654 119.927 24.045 1.00 36.63 ? 86 GLY B C 1 ATOM 4062 O O . GLY C 1 34 ? -12.339 121.000 24.554 1.00 34.91 ? 86 GLY B O 1 ATOM 4063 N N . THR C 1 35 ? -11.846 118.872 24.026 1.00 28.95 ? 87 THR B N 1 ATOM 4064 C CA . THR C 1 35 ? -10.562 118.891 24.715 1.00 29.77 ? 87 THR B CA 1 ATOM 4065 C C . THR C 1 35 ? -9.454 119.539 23.898 1.00 30.99 ? 87 THR B C 1 ATOM 4066 O O . THR C 1 35 ? -8.375 119.804 24.422 1.00 33.14 ? 87 THR B O 1 ATOM 4067 C CB . THR C 1 35 ? -10.116 117.465 25.100 1.00 32.22 ? 87 THR B CB 1 ATOM 4068 O OG1 . THR C 1 35 ? -9.979 116.659 23.922 1.00 35.49 ? 87 THR B OG1 1 ATOM 4069 C CG2 . THR C 1 35 ? -11.130 116.826 26.044 1.00 34.37 ? 87 THR B CG2 1 ATOM 4070 N N . LYS C 1 36 ? -9.713 119.801 22.617 1.00 26.63 ? 88 LYS B N 1 ATOM 4071 C CA . LYS C 1 36 ? -8.740 120.484 21.770 1.00 22.41 ? 88 LYS B CA 1 ATOM 4072 C C . LYS C 1 36 ? -9.084 121.960 21.702 1.00 25.89 ? 88 LYS B C 1 ATOM 4073 O O . LYS C 1 36 ? -10.258 122.318 21.706 1.00 26.49 ? 88 LYS B O 1 ATOM 4074 C CB . LYS C 1 36 ? -8.721 119.892 20.357 1.00 24.10 ? 88 LYS B CB 1 ATOM 4075 C CG . LYS C 1 36 ? -8.548 118.386 20.308 1.00 25.61 ? 88 LYS B CG 1 ATOM 4076 C CD . LYS C 1 36 ? -7.204 117.954 20.867 1.00 28.25 ? 88 LYS B CD 1 ATOM 4077 C CE . LYS C 1 36 ? -7.037 116.449 20.770 1.00 32.90 ? 88 LYS B CE 1 ATOM 4078 N NZ . LYS C 1 36 ? -5.719 116.011 21.286 1.00 39.79 ? 88 LYS B NZ 1 ATOM 4079 N N . SER C 1 37 ? -8.070 122.812 21.631 1.00 25.45 ? 89 SER B N 1 ATOM 4080 C CA . SER C 1 37 ? -8.318 124.242 21.574 1.00 30.98 ? 89 SER B CA 1 ATOM 4081 C C . SER C 1 37 ? -7.214 125.012 20.871 1.00 27.98 ? 89 SER B C 1 ATOM 4082 O O . SER C 1 37 ? -6.062 124.574 20.806 1.00 30.12 ? 89 SER B O 1 ATOM 4083 C CB . SER C 1 37 ? -8.506 124.807 22.987 1.00 32.55 ? 89 SER B CB 1 ATOM 4084 O OG . SER C 1 37 ? -7.256 125.110 23.574 1.00 35.11 ? 89 SER B OG 1 ATOM 4085 N N . HIS C 1 38 ? -7.584 126.175 20.347 1.00 24.95 ? 90 HIS B N 1 ATOM 4086 C CA . HIS C 1 38 ? -6.634 127.077 19.728 1.00 22.27 ? 90 HIS B CA 1 ATOM 4087 C C . HIS C 1 38 ? -7.196 128.482 19.694 1.00 27.91 ? 90 HIS B C 1 ATOM 4088 O O . HIS C 1 38 ? -8.366 128.686 19.358 1.00 27.03 ? 90 HIS B O 1 ATOM 4089 C CB . HIS C 1 38 ? -6.290 126.635 18.308 1.00 27.10 ? 90 HIS B CB 1 ATOM 4090 C CG . HIS C 1 38 ? -5.362 127.568 17.597 1.00 22.02 ? 90 HIS B CG 1 ATOM 4091 N ND1 . HIS C 1 38 ? -4.011 127.627 17.870 1.00 25.05 ? 90 HIS B ND1 1 ATOM 4092 C CD2 . HIS C 1 38 ? -5.588 128.487 16.629 1.00 22.22 ? 90 HIS B CD2 1 ATOM 4093 C CE1 . HIS C 1 38 ? -3.446 128.529 17.090 1.00 22.84 ? 90 HIS B CE1 1 ATOM 4094 N NE2 . HIS C 1 38 ? -4.381 129.066 16.327 1.00 23.81 ? 90 HIS B NE2 1 ATOM 4095 N N . THR C 1 39 ? -6.355 129.446 20.042 1.00 26.56 ? 91 THR B N 1 ATOM 4096 C CA . THR C 1 39 ? -6.754 130.841 20.029 1.00 31.65 ? 91 THR B CA 1 ATOM 4097 C C . THR C 1 39 ? -6.253 131.486 18.748 1.00 28.56 ? 91 THR B C 1 ATOM 4098 O O . THR C 1 39 ? -5.049 131.602 18.520 1.00 29.78 ? 91 THR B O 1 ATOM 4099 C CB . THR C 1 39 ? -6.224 131.589 21.269 1.00 33.20 ? 91 THR B CB 1 ATOM 4100 O OG1 . THR C 1 39 ? -6.783 130.992 22.445 1.00 34.38 ? 91 THR B OG1 1 ATOM 4101 C CG2 . THR C 1 39 ? -6.613 133.064 21.226 1.00 37.44 ? 91 THR B CG2 1 ATOM 4102 N N . ARG C 1 40 ? -7.197 131.875 17.901 1.00 30.03 ? 92 ARG B N 1 ATOM 4103 C CA . ARG C 1 40 ? -6.885 132.515 16.633 1.00 35.76 ? 92 ARG B CA 1 ATOM 4104 C C . ARG C 1 40 ? -7.423 133.936 16.666 1.00 35.10 ? 92 ARG B C 1 ATOM 4105 O O . ARG C 1 40 ? -8.634 134.152 16.682 1.00 35.36 ? 92 ARG B O 1 ATOM 4106 C CB . ARG C 1 40 ? -7.483 131.723 15.469 1.00 28.72 ? 92 ARG B CB 1 ATOM 4107 C CG . ARG C 1 40 ? -7.115 132.246 14.100 1.00 28.55 ? 92 ARG B CG 1 ATOM 4108 C CD . ARG C 1 40 ? -7.928 131.551 13.025 1.00 31.09 ? 92 ARG B CD 1 ATOM 4109 N NE . ARG C 1 40 ? -7.645 132.085 11.697 1.00 26.64 ? 92 ARG B NE 1 ATOM 4110 C CZ . ARG C 1 40 ? -6.706 131.622 10.880 1.00 29.35 ? 92 ARG B CZ 1 ATOM 4111 N NH1 . ARG C 1 40 ? -5.940 130.601 11.243 1.00 31.97 ? 92 ARG B NH1 1 ATOM 4112 N NH2 . ARG C 1 40 ? -6.533 132.183 9.691 1.00 34.48 ? 92 ARG B NH2 1 ATOM 4113 N N . GLY C 1 41 ? -6.514 134.900 16.693 1.00 40.46 ? 93 GLY B N 1 ATOM 4114 C CA . GLY C 1 41 ? -6.891 136.283 16.901 1.00 50.24 ? 93 GLY B CA 1 ATOM 4115 C C . GLY C 1 41 ? -7.344 136.493 18.333 1.00 50.86 ? 93 GLY B C 1 ATOM 4116 O O . GLY C 1 41 ? -6.529 136.481 19.255 1.00 51.42 ? 93 GLY B O 1 ATOM 4117 N N . ASN C 1 42 ? -8.651 136.660 18.517 1.00 48.99 ? 94 ASN B N 1 ATOM 4118 C CA . ASN C 1 42 ? -9.224 136.969 19.824 1.00 50.23 ? 94 ASN B CA 1 ATOM 4119 C C . ASN C 1 42 ? -10.246 135.927 20.268 1.00 51.05 ? 94 ASN B C 1 ATOM 4120 O O . ASN C 1 42 ? -10.795 136.004 21.370 1.00 51.15 ? 94 ASN B O 1 ATOM 4121 C CB . ASN C 1 42 ? -9.863 138.359 19.790 1.00 59.99 ? 94 ASN B CB 1 ATOM 4122 C CG . ASN C 1 42 ? -8.836 139.465 19.627 1.00 70.50 ? 94 ASN B CG 1 ATOM 4123 O OD1 . ASN C 1 42 ? -7.697 139.339 20.077 1.00 76.02 ? 94 ASN B OD1 1 ATOM 4124 N ND2 . ASN C 1 42 ? -9.233 140.553 18.976 1.00 76.43 ? 94 ASN B ND2 1 ATOM 4125 N N . THR C 1 43 ? -10.487 134.948 19.402 1.00 41.45 ? 95 THR B N 1 ATOM 4126 C CA . THR C 1 43 ? -11.402 133.857 19.694 1.00 36.24 ? 95 THR B CA 1 ATOM 4127 C C . THR C 1 43 ? -10.620 132.599 20.036 1.00 30.59 ? 95 THR B C 1 ATOM 4128 O O . THR C 1 43 ? -9.643 132.280 19.361 1.00 32.52 ? 95 THR B O 1 ATOM 4129 C CB . THR C 1 43 ? -12.319 133.564 18.498 1.00 37.64 ? 95 THR B CB 1 ATOM 4130 O OG1 . THR C 1 43 ? -13.041 134.752 18.153 1.00 46.14 ? 95 THR B OG1 1 ATOM 4131 C CG2 . THR C 1 43 ? -13.300 132.440 18.820 1.00 34.67 ? 95 THR B CG2 1 ATOM 4132 N N . THR C 1 44 ? -11.048 131.896 21.080 1.00 29.10 ? 96 THR B N 1 ATOM 4133 C CA . THR C 1 44 ? -10.515 130.568 21.370 1.00 32.98 ? 96 THR B CA 1 ATOM 4134 C C . THR C 1 44 ? -11.519 129.534 20.873 1.00 28.69 ? 96 THR B C 1 ATOM 4135 O O . THR C 1 44 ? -12.660 129.485 21.333 1.00 30.05 ? 96 THR B O 1 ATOM 4136 C CB . THR C 1 44 ? -10.228 130.360 22.879 1.00 31.67 ? 96 THR B CB 1 ATOM 4137 O OG1 . THR C 1 44 ? -9.281 131.335 23.330 1.00 29.31 ? 96 THR B OG1 1 ATOM 4138 C CG2 . THR C 1 44 ? -9.653 128.971 23.132 1.00 33.82 ? 96 THR B CG2 1 ATOM 4139 N N . TYR C 1 45 ? -11.089 128.725 19.908 1.00 27.26 ? 97 TYR B N 1 ATOM 4140 C CA . TYR C 1 45 ? -11.922 127.669 19.348 1.00 24.38 ? 97 TYR B CA 1 ATOM 4141 C C . TYR C 1 45 ? -11.719 126.364 20.098 1.00 21.03 ? 97 TYR B C 1 ATOM 4142 O O . TYR C 1 45 ? -10.599 126.054 20.486 1.00 26.49 ? 97 TYR B O 1 ATOM 4143 C CB . TYR C 1 45 ? -11.597 127.471 17.867 1.00 23.96 ? 97 TYR B CB 1 ATOM 4144 C CG . TYR C 1 45 ? -11.855 128.703 17.038 1.00 20.59 ? 97 TYR B CG 1 ATOM 4145 C CD1 . TYR C 1 45 ? -10.874 129.671 16.871 1.00 21.66 ? 97 TYR B CD1 1 ATOM 4146 C CD2 . TYR C 1 45 ? -13.090 128.912 16.440 1.00 21.74 ? 97 TYR B CD2 1 ATOM 4147 C CE1 . TYR C 1 45 ? -11.113 130.809 16.121 1.00 23.42 ? 97 TYR B CE1 1 ATOM 4148 C CE2 . TYR C 1 45 ? -13.335 130.041 15.693 1.00 22.05 ? 97 TYR B CE2 1 ATOM 4149 C CZ . TYR C 1 45 ? -12.347 130.985 15.534 1.00 22.68 ? 97 TYR B CZ 1 ATOM 4150 O OH . TYR C 1 45 ? -12.597 132.113 14.790 1.00 28.97 ? 97 TYR B OH 1 ATOM 4151 N N . ARG C 1 46 ? -12.794 125.605 20.280 1.00 21.24 ? 98 ARG B N 1 ATOM 4152 C CA . ARG C 1 46 ? -12.725 124.305 20.946 1.00 26.17 ? 98 ARG B CA 1 ATOM 4153 C C . ARG C 1 46 ? -13.395 123.197 20.148 1.00 24.92 ? 98 ARG B C 1 ATOM 4154 O O . ARG C 1 46 ? -14.514 123.360 19.648 1.00 24.94 ? 98 ARG B O 1 ATOM 4155 C CB . ARG C 1 46 ? -13.369 124.379 22.327 1.00 29.65 ? 98 ARG B CB 1 ATOM 4156 C CG . ARG C 1 46 ? -12.649 125.304 23.257 1.00 35.79 ? 98 ARG B CG 1 ATOM 4157 C CD . ARG C 1 46 ? -13.272 125.303 24.645 1.00 46.04 ? 98 ARG B CD 1 ATOM 4158 N NE . ARG C 1 46 ? -12.409 125.946 25.636 1.00 57.78 ? 98 ARG B NE 1 ATOM 4159 C CZ . ARG C 1 46 ? -11.977 127.205 25.574 1.00 62.20 ? 98 ARG B CZ 1 ATOM 4160 N NH1 . ARG C 1 46 ? -12.315 127.998 24.564 1.00 62.47 ? 98 ARG B NH1 1 ATOM 4161 N NH2 . ARG C 1 46 ? -11.194 127.679 26.533 1.00 59.14 ? 98 ARG B NH2 1 ATOM 4162 N N . TRP C 1 47 ? -12.721 122.052 20.064 1.00 22.90 ? 99 TRP B N 1 ATOM 4163 C CA . TRP C 1 47 ? -13.239 120.940 19.284 1.00 21.24 ? 99 TRP B CA 1 ATOM 4164 C C . TRP C 1 47 ? -12.884 119.565 19.854 1.00 24.21 ? 99 TRP B C 1 ATOM 4165 O O . TRP C 1 47 ? -11.992 119.434 20.699 1.00 25.83 ? 99 TRP B O 1 ATOM 4166 C CB . TRP C 1 47 ? -12.744 121.055 17.834 1.00 19.90 ? 99 TRP B CB 1 ATOM 4167 C CG . TRP C 1 47 ? -11.264 120.883 17.599 1.00 20.66 ? 99 TRP B CG 1 ATOM 4168 C CD1 . TRP C 1 47 ? -10.613 119.719 17.297 1.00 19.35 ? 99 TRP B CD1 1 ATOM 4169 C CD2 . TRP C 1 47 ? -10.266 121.911 17.588 1.00 18.81 ? 99 TRP B CD2 1 ATOM 4170 N NE1 . TRP C 1 47 ? -9.274 119.961 17.110 1.00 17.82 ? 99 TRP B NE1 1 ATOM 4171 C CE2 . TRP C 1 47 ? -9.034 121.297 17.284 1.00 19.97 ? 99 TRP B CE2 1 ATOM 4172 C CE3 . TRP C 1 47 ? -10.293 123.293 17.815 1.00 21.19 ? 99 TRP B CE3 1 ATOM 4173 C CZ2 . TRP C 1 47 ? -7.848 122.012 17.205 1.00 18.92 ? 99 TRP B CZ2 1 ATOM 4174 C CZ3 . TRP C 1 47 ? -9.117 123.998 17.735 1.00 20.55 ? 99 TRP B CZ3 1 ATOM 4175 C CH2 . TRP C 1 47 ? -7.908 123.362 17.433 1.00 25.30 ? 99 TRP B CH2 1 ATOM 4176 N N . THR C 1 48 ? -13.638 118.563 19.407 1.00 23.39 ? 100 THR B N 1 ATOM 4177 C CA . THR C 1 48 ? -13.336 117.155 19.646 1.00 20.70 ? 100 THR B CA 1 ATOM 4178 C C . THR C 1 48 ? -12.699 116.596 18.378 1.00 20.36 ? 100 THR B C 1 ATOM 4179 O O . THR C 1 48 ? -13.251 116.768 17.294 1.00 20.02 ? 100 THR B O 1 ATOM 4180 C CB . THR C 1 48 ? -14.607 116.336 19.986 1.00 23.22 ? 100 THR B CB 1 ATOM 4181 O OG1 . THR C 1 48 ? -15.145 116.765 21.244 1.00 32.61 ? 100 THR B OG1 1 ATOM 4182 C CG2 . THR C 1 48 ? -14.307 114.839 20.052 1.00 27.70 ? 100 THR B CG2 1 ATOM 4183 N N . GLU C 1 49 ? -11.544 115.945 18.503 1.00 19.82 ? 101 GLU B N 1 ATOM 4184 C CA . GLU C 1 49 ? -10.965 115.214 17.379 1.00 18.19 ? 101 GLU B CA 1 ATOM 4185 C C . GLU C 1 49 ? -11.517 113.792 17.380 1.00 19.75 ? 101 GLU B C 1 ATOM 4186 O O . GLU C 1 49 ? -11.192 112.994 18.260 1.00 22.92 ? 101 GLU B O 1 ATOM 4187 C CB . GLU C 1 49 ? -9.439 115.193 17.452 1.00 18.53 ? 101 GLU B CB 1 ATOM 4188 C CG . GLU C 1 49 ? -8.797 114.458 16.283 1.00 18.00 ? 101 GLU B CG 1 ATOM 4189 C CD . GLU C 1 49 ? -7.279 114.446 16.335 1.00 26.78 ? 101 GLU B CD 1 ATOM 4190 O OE1 . GLU C 1 49 ? -6.669 115.515 16.589 1.00 21.24 ? 101 GLU B OE1 1 ATOM 4191 O OE2 . GLU C 1 49 ? -6.694 113.358 16.109 1.00 21.41 ? 101 GLU B OE2 1 ATOM 4192 N N . ARG C 1 50 ? -12.355 113.476 16.402 1.00 16.00 ? 102 ARG B N 1 ATOM 4193 C CA . ARG C 1 50 ? -13.013 112.174 16.351 1.00 17.48 ? 102 ARG B CA 1 ATOM 4194 C C . ARG C 1 50 ? -12.111 111.109 15.744 1.00 18.64 ? 102 ARG B C 1 ATOM 4195 O O . ARG C 1 50 ? -12.134 109.956 16.169 1.00 19.22 ? 102 ARG B O 1 ATOM 4196 C CB . ARG C 1 50 ? -14.322 112.267 15.559 1.00 17.22 ? 102 ARG B CB 1 ATOM 4197 C CG . ARG C 1 50 ? -15.363 113.192 16.193 1.00 18.84 ? 102 ARG B CG 1 ATOM 4198 C CD . ARG C 1 50 ? -16.763 112.906 15.674 1.00 19.02 ? 102 ARG B CD 1 ATOM 4199 N NE . ARG C 1 50 ? -16.857 113.039 14.220 1.00 17.33 ? 102 ARG B NE 1 ATOM 4200 C CZ . ARG C 1 50 ? -17.957 112.807 13.512 1.00 16.32 ? 102 ARG B CZ 1 ATOM 4201 N NH1 . ARG C 1 50 ? -17.931 112.949 12.191 1.00 14.98 ? 102 ARG B NH1 1 ATOM 4202 N NH2 . ARG C 1 50 ? -19.080 112.422 14.113 1.00 17.18 ? 102 ARG B NH2 1 ATOM 4203 N N . LYS C 1 51 ? -11.328 111.490 14.743 1.00 15.23 ? 103 LYS B N 1 ATOM 4204 C CA . LYS C 1 51 ? -10.374 110.570 14.139 1.00 16.70 ? 103 LYS B CA 1 ATOM 4205 C C . LYS C 1 51 ? -9.311 111.347 13.381 1.00 16.61 ? 103 LYS B C 1 ATOM 4206 O O . LYS C 1 51 ? -9.504 112.513 13.027 1.00 16.86 ? 103 LYS B O 1 ATOM 4207 C CB . LYS C 1 51 ? -11.069 109.578 13.198 1.00 19.05 ? 103 LYS B CB 1 ATOM 4208 C CG . LYS C 1 51 ? -11.579 110.164 11.891 1.00 21.36 ? 103 LYS B CG 1 ATOM 4209 C CD . LYS C 1 51 ? -12.304 109.113 11.031 1.00 24.13 ? 103 LYS B CD 1 ATOM 4210 C CE . LYS C 1 51 ? -11.386 107.981 10.580 1.00 40.33 ? 103 LYS B CE 1 ATOM 4211 N NZ . LYS C 1 51 ? -10.283 108.450 9.687 1.00 42.03 ? 103 LYS B NZ 1 ATOM 4212 N N . SER C 1 52 ? -8.180 110.699 13.144 1.00 14.96 ? 104 SER B N 1 ATOM 4213 C CA . SER C 1 52 ? -7.143 111.273 12.307 1.00 15.40 ? 104 SER B CA 1 ATOM 4214 C C . SER C 1 52 ? -7.158 110.592 10.949 1.00 11.98 ? 104 SER B C 1 ATOM 4215 O O . SER C 1 52 ? -8.010 109.747 10.680 1.00 14.11 ? 104 SER B O 1 ATOM 4216 C CB . SER C 1 52 ? -5.778 111.138 12.973 1.00 16.26 ? 104 SER B CB 1 ATOM 4217 O OG . SER C 1 52 ? -5.432 109.785 13.146 1.00 16.96 ? 104 SER B OG 1 ATOM 4218 N N . ASN C 1 53 ? -6.242 111.000 10.085 1.00 14.43 ? 105 ASN B N 1 ATOM 4219 C CA . ASN C 1 53 ? -6.036 110.358 8.792 1.00 12.91 ? 105 ASN B CA 1 ATOM 4220 C C . ASN C 1 53 ? -7.286 110.354 7.907 1.00 13.25 ? 105 ASN B C 1 ATOM 4221 O O . ASN C 1 53 ? -7.625 109.352 7.278 1.00 13.83 ? 105 ASN B O 1 ATOM 4222 C CB . ASN C 1 53 ? -5.532 108.927 9.012 1.00 13.10 ? 105 ASN B CB 1 ATOM 4223 C CG . ASN C 1 53 ? -4.878 108.332 7.775 1.00 16.39 ? 105 ASN B CG 1 ATOM 4224 O OD1 . ASN C 1 53 ? -4.322 109.039 6.935 1.00 14.35 ? 105 ASN B OD1 1 ATOM 4225 N ND2 . ASN C 1 53 ? -4.947 107.010 7.660 1.00 26.78 ? 105 ASN B ND2 1 ATOM 4226 N N . VAL C 1 54 ? -7.973 111.488 7.853 1.00 11.45 ? 106 VAL B N 1 ATOM 4227 C CA . VAL C 1 54 ? -9.093 111.638 6.937 1.00 11.10 ? 106 VAL B CA 1 ATOM 4228 C C . VAL C 1 54 ? -8.568 111.593 5.504 1.00 10.21 ? 106 VAL B C 1 ATOM 4229 O O . VAL C 1 54 ? -7.464 112.064 5.233 1.00 10.94 ? 106 VAL B O 1 ATOM 4230 C CB . VAL C 1 54 ? -9.838 112.959 7.191 1.00 11.97 ? 106 VAL B CB 1 ATOM 4231 C CG1 . VAL C 1 54 ? -10.948 113.183 6.167 1.00 12.74 ? 106 VAL B CG1 1 ATOM 4232 C CG2 . VAL C 1 54 ? -10.406 112.969 8.595 1.00 12.34 ? 106 VAL B CG2 1 ATOM 4233 N N . GLY C 1 55 ? -9.352 111.028 4.587 1.00 10.25 ? 107 GLY B N 1 ATOM 4234 C CA . GLY C 1 55 ? -8.964 110.996 3.185 1.00 9.91 ? 107 GLY B CA 1 ATOM 4235 C C . GLY C 1 55 ? -8.708 112.376 2.605 1.00 10.39 ? 107 GLY B C 1 ATOM 4236 O O . GLY C 1 55 ? -9.487 113.306 2.839 1.00 12.39 ? 107 GLY B O 1 ATOM 4237 N N . VAL C 1 56 ? -7.617 112.504 1.855 1.00 9.15 ? 108 VAL B N 1 ATOM 4238 C CA . VAL C 1 56 ? -7.216 113.779 1.253 1.00 8.70 ? 108 VAL B CA 1 ATOM 4239 C C . VAL C 1 56 ? -7.845 113.965 -0.126 1.00 10.87 ? 108 VAL B C 1 ATOM 4240 O O . VAL C 1 56 ? -8.405 115.024 -0.420 1.00 11.00 ? 108 VAL B O 1 ATOM 4241 C CB . VAL C 1 56 ? -5.670 113.871 1.170 1.00 9.65 ? 108 VAL B CB 1 ATOM 4242 C CG1 . VAL C 1 56 ? -5.195 115.046 0.307 1.00 10.82 ? 108 VAL B CG1 1 ATOM 4243 C CG2 . VAL C 1 56 ? -5.073 113.954 2.576 1.00 11.73 ? 108 VAL B CG2 1 ATOM 4244 N N . TYR C 1 57 ? -7.755 112.946 -0.979 1.00 10.20 ? 109 TYR B N 1 ATOM 4245 C CA . TYR C 1 57 ? -8.387 113.001 -2.299 1.00 9.95 ? 109 TYR B CA 1 ATOM 4246 C C . TYR C 1 57 ? -9.907 113.151 -2.120 1.00 9.34 ? 109 TYR B C 1 ATOM 4247 O O . TYR C 1 57 ? -10.531 114.046 -2.693 1.00 10.59 ? 109 TYR B O 1 ATOM 4248 C CB . TYR C 1 57 ? -8.035 111.748 -3.102 1.00 9.77 ? 109 TYR B CB 1 ATOM 4249 C CG . TYR C 1 57 ? -8.429 111.788 -4.561 1.00 10.25 ? 109 TYR B CG 1 ATOM 4250 C CD1 . TYR C 1 57 ? -7.813 112.659 -5.449 1.00 12.30 ? 109 TYR B CD1 1 ATOM 4251 C CD2 . TYR C 1 57 ? -9.403 110.950 -5.046 1.00 11.31 ? 109 TYR B CD2 1 ATOM 4252 C CE1 . TYR C 1 57 ? -8.166 112.690 -6.784 1.00 12.14 ? 109 TYR B CE1 1 ATOM 4253 C CE2 . TYR C 1 57 ? -9.765 110.971 -6.376 1.00 9.85 ? 109 TYR B CE2 1 ATOM 4254 C CZ . TYR C 1 57 ? -9.142 111.839 -7.245 1.00 13.32 ? 109 TYR B CZ 1 ATOM 4255 O OH . TYR C 1 57 ? -9.495 111.853 -8.578 1.00 15.24 ? 109 TYR B OH 1 ATOM 4256 N N . VAL C 1 58 ? -10.474 112.270 -1.294 1.00 9.19 ? 110 VAL B N 1 ATOM 4257 C CA . VAL C 1 58 ? -11.879 112.280 -0.917 1.00 10.12 ? 110 VAL B CA 1 ATOM 4258 C C . VAL C 1 58 ? -11.941 112.109 0.596 1.00 9.60 ? 110 VAL B C 1 ATOM 4259 O O . VAL C 1 58 ? -11.456 111.109 1.116 1.00 10.84 ? 110 VAL B O 1 ATOM 4260 C CB . VAL C 1 58 ? -12.663 111.140 -1.619 1.00 9.81 ? 110 VAL B CB 1 ATOM 4261 C CG1 . VAL C 1 58 ? -14.077 111.012 -1.074 1.00 12.04 ? 110 VAL B CG1 1 ATOM 4262 C CG2 . VAL C 1 58 ? -12.686 111.343 -3.138 1.00 10.99 ? 110 VAL B CG2 1 ATOM 4263 N N . GLY C 1 59 ? -12.543 113.057 1.312 1.00 9.95 ? 111 GLY B N 1 ATOM 4264 C CA . GLY C 1 59 ? -12.623 112.986 2.762 1.00 10.25 ? 111 GLY B CA 1 ATOM 4265 C C . GLY C 1 59 ? -14.053 113.000 3.261 1.00 10.57 ? 111 GLY B C 1 ATOM 4266 O O . GLY C 1 59 ? -14.818 113.913 2.928 1.00 10.49 ? 111 GLY B O 1 ATOM 4267 N N . TYR C 1 60 ? -14.401 111.990 4.053 1.00 10.47 ? 112 TYR B N 1 ATOM 4268 C CA . TYR C 1 60 ? -15.730 111.859 4.639 1.00 12.49 ? 112 TYR B CA 1 ATOM 4269 C C . TYR C 1 60 ? -15.645 111.503 6.109 1.00 13.64 ? 112 TYR B C 1 ATOM 4270 O O . TYR C 1 60 ? -14.725 110.802 6.545 1.00 15.12 ? 112 TYR B O 1 ATOM 4271 C CB . TYR C 1 60 ? -16.559 110.761 3.961 1.00 11.82 ? 112 TYR B CB 1 ATOM 4272 C CG . TYR C 1 60 ? -16.872 110.970 2.504 1.00 10.91 ? 112 TYR B CG 1 ATOM 4273 C CD1 . TYR C 1 60 ? -17.446 112.152 2.053 1.00 11.90 ? 112 TYR B CD1 1 ATOM 4274 C CD2 . TYR C 1 60 ? -16.609 109.975 1.579 1.00 10.88 ? 112 TYR B CD2 1 ATOM 4275 C CE1 . TYR C 1 60 ? -17.729 112.335 0.716 1.00 12.46 ? 112 TYR B CE1 1 ATOM 4276 C CE2 . TYR C 1 60 ? -16.886 110.148 0.240 1.00 11.32 ? 112 TYR B CE2 1 ATOM 4277 C CZ . TYR C 1 60 ? -17.447 111.338 -0.191 1.00 11.05 ? 112 TYR B CZ 1 ATOM 4278 O OH . TYR C 1 60 ? -17.728 111.523 -1.525 1.00 13.93 ? 112 TYR B OH 1 ATOM 4279 N N . SER C 1 61 ? -16.655 111.930 6.853 1.00 12.53 ? 113 SER B N 1 ATOM 4280 C CA . SER C 1 61 ? -16.905 111.384 8.178 1.00 13.34 ? 113 SER B CA 1 ATOM 4281 C C . SER C 1 61 ? -18.407 111.336 8.403 1.00 14.83 ? 113 SER B C 1 ATOM 4282 O O . SER C 1 61 ? -19.170 111.926 7.639 1.00 13.61 ? 113 SER B O 1 ATOM 4283 C CB . SER C 1 61 ? -16.225 112.218 9.252 1.00 16.68 ? 113 SER B CB 1 ATOM 4284 O OG . SER C 1 61 ? -16.801 113.504 9.311 1.00 15.49 ? 113 SER B OG 1 ATOM 4285 N N . GLU C 1 62 ? -18.836 110.632 9.443 1.00 15.00 ? 114 GLU B N 1 ATOM 4286 C CA . GLU C 1 62 ? -20.261 110.502 9.723 1.00 14.64 ? 114 GLU B CA 1 ATOM 4287 C C . GLU C 1 62 ? -20.907 111.867 9.938 1.00 15.75 ? 114 GLU B C 1 ATOM 4288 O O . GLU C 1 62 ? -20.393 112.697 10.687 1.00 15.10 ? 114 GLU B O 1 ATOM 4289 C CB . GLU C 1 62 ? -20.504 109.624 10.959 1.00 15.43 ? 114 GLU B CB 1 ATOM 4290 C CG . GLU C 1 62 ? -19.928 108.218 10.880 1.00 20.91 ? 114 GLU B CG 1 ATOM 4291 C CD . GLU C 1 62 ? -18.525 108.110 11.475 1.00 29.82 ? 114 GLU B CD 1 ATOM 4292 O OE1 . GLU C 1 62 ? -17.674 108.977 11.188 1.00 23.55 ? 114 GLU B OE1 1 ATOM 4293 O OE2 . GLU C 1 62 ? -18.271 107.157 12.246 1.00 33.37 ? 114 GLU B OE2 1 ATOM 4294 N N . MET C 1 63 ? -22.037 112.097 9.272 1.00 17.79 ? 115 MET B N 1 ATOM 4295 C CA . MET C 1 63 ? -22.803 113.311 9.496 1.00 20.77 ? 115 MET B CA 1 ATOM 4296 C C . MET C 1 63 ? -23.043 113.476 10.996 1.00 17.98 ? 115 MET B C 1 ATOM 4297 O O . MET C 1 63 ? -23.485 112.551 11.676 1.00 20.91 ? 115 MET B O 1 ATOM 4298 C CB . MET C 1 63 ? -24.132 113.274 8.729 1.00 22.39 ? 115 MET B CB 1 ATOM 4299 C CG . MET C 1 63 ? -25.072 114.440 9.042 1.00 26.90 ? 115 MET B CG 1 ATOM 4300 S SD . MET C 1 63 ? -24.380 116.073 8.750 1.00 24.56 ? 115 MET B SD 1 ATOM 4301 C CE . MET C 1 63 ? -24.543 116.223 6.961 1.00 20.60 ? 115 MET B CE 1 ATOM 4302 N N . TYR C 1 64 ? -22.694 114.653 11.486 1.00 17.94 ? 116 TYR B N 1 ATOM 4303 C CA . TYR C 1 64 ? -22.827 115.000 12.894 1.00 21.65 ? 116 TYR B CA 1 ATOM 4304 C C . TYR C 1 64 ? -23.770 116.183 13.044 1.00 19.56 ? 116 TYR B C 1 ATOM 4305 O O . TYR C 1 64 ? -23.462 117.285 12.593 1.00 19.35 ? 116 TYR B O 1 ATOM 4306 C CB . TYR C 1 64 ? -21.456 115.322 13.479 1.00 21.78 ? 116 TYR B CB 1 ATOM 4307 C CG . TYR C 1 64 ? -21.465 115.722 14.931 1.00 22.05 ? 116 TYR B CG 1 ATOM 4308 C CD1 . TYR C 1 64 ? -21.491 114.764 15.934 1.00 25.13 ? 116 TYR B CD1 1 ATOM 4309 C CD2 . TYR C 1 64 ? -21.429 117.056 15.298 1.00 19.76 ? 116 TYR B CD2 1 ATOM 4310 C CE1 . TYR C 1 64 ? -21.489 115.129 17.263 1.00 23.96 ? 116 TYR B CE1 1 ATOM 4311 C CE2 . TYR C 1 64 ? -21.426 117.435 16.625 1.00 19.90 ? 116 TYR B CE2 1 ATOM 4312 C CZ . TYR C 1 64 ? -21.459 116.465 17.603 1.00 24.38 ? 116 TYR B CZ 1 ATOM 4313 O OH . TYR C 1 64 ? -21.455 116.840 18.927 1.00 24.99 ? 116 TYR B OH 1 ATOM 4314 N N . ASP C 1 65 ? -24.913 115.942 13.683 1.00 21.71 ? 117 ASP B N 1 ATOM 4315 C CA . ASP C 1 65 ? -25.908 116.986 13.908 1.00 19.12 ? 117 ASP B CA 1 ATOM 4316 C C . ASP C 1 65 ? -26.200 117.116 15.406 1.00 19.78 ? 117 ASP B C 1 ATOM 4317 O O . ASP C 1 65 ? -26.925 116.302 15.984 1.00 22.86 ? 117 ASP B O 1 ATOM 4318 C CB . ASP C 1 65 ? -27.189 116.686 13.131 1.00 17.73 ? 117 ASP B CB 1 ATOM 4319 C CG . ASP C 1 65 ? -28.105 117.891 13.033 1.00 22.52 ? 117 ASP B CG 1 ATOM 4320 O OD1 . ASP C 1 65 ? -28.101 118.708 13.974 1.00 22.31 ? 117 ASP B OD1 1 ATOM 4321 O OD2 . ASP C 1 65 ? -28.821 118.020 12.013 1.00 21.88 ? 117 ASP B OD2 1 ATOM 4322 N N . SER C 1 66 ? -25.629 118.149 16.013 1.00 22.63 ? 118 SER B N 1 ATOM 4323 C CA . SER C 1 66 ? -25.814 118.412 17.437 1.00 23.15 ? 118 SER B CA 1 ATOM 4324 C C . SER C 1 66 ? -26.786 119.564 17.672 1.00 25.85 ? 118 SER B C 1 ATOM 4325 O O . SER C 1 66 ? -26.730 120.227 18.710 1.00 24.42 ? 118 SER B O 1 ATOM 4326 C CB . SER C 1 66 ? -24.476 118.716 18.108 1.00 24.22 ? 118 SER B CB 1 ATOM 4327 O OG . SER C 1 66 ? -23.853 119.841 17.536 1.00 24.07 ? 118 SER B OG 1 ATOM 4328 N N . SER C 1 67 ? -27.664 119.808 16.701 1.00 21.93 ? 119 SER B N 1 ATOM 4329 C CA . SER C 1 67 ? -28.822 120.663 16.936 1.00 23.37 ? 119 SER B CA 1 ATOM 4330 C C . SER C 1 67 ? -29.745 119.908 17.891 1.00 22.02 ? 119 SER B C 1 ATOM 4331 O O . SER C 1 67 ? -29.638 118.690 18.033 1.00 24.49 ? 119 SER B O 1 ATOM 4332 C CB . SER C 1 67 ? -29.544 121.016 15.624 1.00 18.27 ? 119 SER B CB 1 ATOM 4333 O OG . SER C 1 67 ? -30.183 119.895 15.047 1.00 22.09 ? 119 SER B OG 1 ATOM 4334 N N . ALA C 1 68 ? -30.645 120.626 18.554 1.00 28.39 ? 120 ALA B N 1 ATOM 4335 C CA . ALA C 1 68 ? -31.564 120.000 19.504 1.00 23.90 ? 120 ALA B CA 1 ATOM 4336 C C . ALA C 1 68 ? -32.407 118.910 18.853 1.00 24.68 ? 120 ALA B C 1 ATOM 4337 O O . ALA C 1 68 ? -32.692 117.887 19.471 1.00 30.51 ? 120 ALA B O 1 ATOM 4338 C CB . ALA C 1 68 ? -32.460 121.058 20.134 1.00 28.35 ? 120 ALA B CB 1 ATOM 4339 N N . GLN C 1 69 ? -32.787 119.115 17.595 1.00 23.86 ? 121 GLN B N 1 ATOM 4340 C CA . GLN C 1 69 ? -33.622 118.154 16.879 1.00 24.90 ? 121 GLN B CA 1 ATOM 4341 C C . GLN C 1 69 ? -32.810 117.122 16.090 1.00 19.98 ? 121 GLN B C 1 ATOM 4342 O O . GLN C 1 69 ? -33.362 116.120 15.624 1.00 25.93 ? 121 GLN B O 1 ATOM 4343 C CB . GLN C 1 69 ? -34.568 118.895 15.932 1.00 28.32 ? 121 GLN B CB 1 ATOM 4344 C CG . GLN C 1 69 ? -35.547 119.814 16.639 1.00 27.72 ? 121 GLN B CG 1 ATOM 4345 C CD . GLN C 1 69 ? -36.316 119.107 17.737 1.00 26.06 ? 121 GLN B CD 1 ATOM 4346 O OE1 . GLN C 1 69 ? -36.920 118.058 17.514 1.00 36.61 ? 121 GLN B OE1 1 ATOM 4347 N NE2 . GLN C 1 69 ? -36.286 119.673 18.935 1.00 32.32 ? 121 GLN B NE2 1 ATOM 4348 N N . ALA C 1 70 ? -31.511 117.376 15.942 1.00 23.97 ? 122 ALA B N 1 ATOM 4349 C CA . ALA C 1 70 ? -30.614 116.479 15.206 1.00 25.67 ? 122 ALA B CA 1 ATOM 4350 C C . ALA C 1 70 ? -31.156 116.160 13.811 1.00 21.89 ? 122 ALA B C 1 ATOM 4351 O O . ALA C 1 70 ? -31.095 115.019 13.354 1.00 23.09 ? 122 ALA B O 1 ATOM 4352 C CB . ALA C 1 70 ? -30.387 115.186 16.007 1.00 25.21 ? 122 ALA B CB 1 ATOM 4353 N N . TYR C 1 71 ? -31.671 117.189 13.136 1.00 23.78 ? 123 TYR B N 1 ATOM 4354 C CA . TYR C 1 71 ? -32.379 117.030 11.867 1.00 22.31 ? 123 TYR B CA 1 ATOM 4355 C C . TYR C 1 71 ? -31.699 116.099 10.866 1.00 20.97 ? 123 TYR B C 1 ATOM 4356 O O . TYR C 1 71 ? -32.321 115.188 10.327 1.00 24.20 ? 123 TYR B O 1 ATOM 4357 C CB . TYR C 1 71 ? -32.559 118.397 11.195 1.00 22.56 ? 123 TYR B CB 1 ATOM 4358 C CG . TYR C 1 71 ? -33.384 119.379 11.984 1.00 19.64 ? 123 TYR B CG 1 ATOM 4359 C CD1 . TYR C 1 71 ? -34.759 119.229 12.087 1.00 21.56 ? 123 TYR B CD1 1 ATOM 4360 C CD2 . TYR C 1 71 ? -32.792 120.465 12.609 1.00 18.90 ? 123 TYR B CD2 1 ATOM 4361 C CE1 . TYR C 1 71 ? -35.520 120.129 12.807 1.00 22.51 ? 123 TYR B CE1 1 ATOM 4362 C CE2 . TYR C 1 71 ? -33.545 121.373 13.330 1.00 21.76 ? 123 TYR B CE2 1 ATOM 4363 C CZ . TYR C 1 71 ? -34.910 121.195 13.421 1.00 21.75 ? 123 TYR B CZ 1 ATOM 4364 O OH . TYR C 1 71 ? -35.675 122.089 14.131 1.00 24.90 ? 123 TYR B OH 1 ATOM 4365 N N . CYS C 1 72 ? -30.423 116.352 10.607 1.00 22.61 ? 124 CYS B N 1 ATOM 4366 C CA . CYS C 1 72 ? -29.745 115.693 9.498 1.00 21.90 ? 124 CYS B CA 1 ATOM 4367 C C . CYS C 1 72 ? -29.221 114.308 9.870 1.00 27.78 ? 124 CYS B C 1 ATOM 4368 O O . CYS C 1 72 ? -28.536 113.676 9.074 1.00 27.11 ? 124 CYS B O 1 ATOM 4369 C CB . CYS C 1 72 ? -28.605 116.579 8.988 1.00 21.15 ? 124 CYS B CB 1 ATOM 4370 S SG . CYS C 1 72 ? -29.175 118.158 8.268 1.00 22.75 ? 124 CYS B SG 1 ATOM 4371 N N . GLN C 1 73 ? -29.560 113.833 11.067 1.00 27.20 ? 125 GLN B N 1 ATOM 4372 C CA . GLN C 1 73 ? -29.258 112.454 11.452 1.00 28.47 ? 125 GLN B CA 1 ATOM 4373 C C . GLN C 1 73 ? -30.500 111.571 11.502 1.00 35.27 ? 125 GLN B C 1 ATOM 4374 O O . GLN C 1 73 ? -30.414 110.388 11.832 1.00 34.57 ? 125 GLN B O 1 ATOM 4375 C CB . GLN C 1 73 ? -28.546 112.424 12.797 1.00 26.58 ? 125 GLN B CB 1 ATOM 4376 C CG . GLN C 1 73 ? -27.103 112.856 12.695 1.00 31.36 ? 125 GLN B CG 1 ATOM 4377 C CD . GLN C 1 73 ? -26.285 112.417 13.877 1.00 25.15 ? 125 GLN B CD 1 ATOM 4378 O OE1 . GLN C 1 73 ? -25.625 113.227 14.521 1.00 24.25 ? 125 GLN B OE1 1 ATOM 4379 N NE2 . GLN C 1 73 ? -26.308 111.119 14.161 1.00 33.42 ? 125 GLN B NE2 1 ATOM 4380 N N . SER C 1 74 ? -31.653 112.134 11.161 1.00 28.37 ? 126 SER B N 1 ATOM 4381 C CA . SER C 1 74 ? -32.855 111.330 10.985 1.00 30.33 ? 126 SER B CA 1 ATOM 4382 C C . SER C 1 74 ? -32.731 110.421 9.764 1.00 37.87 ? 126 SER B C 1 ATOM 4383 O O . SER C 1 74 ? -32.017 110.738 8.813 1.00 40.95 ? 126 SER B O 1 ATOM 4384 C CB . SER C 1 74 ? -34.086 112.215 10.835 1.00 26.99 ? 126 SER B CB 1 ATOM 4385 O OG . SER C 1 74 ? -35.151 111.472 10.267 1.00 35.99 ? 126 SER B OG 1 ATOM 4386 N N . SER C 1 75 ? -33.451 109.305 9.784 1.00 42.19 ? 127 SER B N 1 ATOM 4387 C CA . SER C 1 75 ? -33.372 108.314 8.718 1.00 36.13 ? 127 SER B CA 1 ATOM 4388 C C . SER C 1 75 ? -34.222 108.704 7.513 1.00 36.92 ? 127 SER B C 1 ATOM 4389 O O . SER C 1 75 ? -34.153 108.064 6.463 1.00 41.10 ? 127 SER B O 1 ATOM 4390 C CB . SER C 1 75 ? -33.805 106.946 9.246 1.00 47.39 ? 127 SER B CB 1 ATOM 4391 O OG . SER C 1 75 ? -33.035 106.586 10.381 1.00 50.06 ? 127 SER B OG 1 ATOM 4392 N N . SER C 1 76 ? -35.026 109.750 7.665 1.00 34.97 ? 128 SER B N 1 ATOM 4393 C CA . SER C 1 76 ? -35.804 110.273 6.549 1.00 36.23 ? 128 SER B CA 1 ATOM 4394 C C . SER C 1 76 ? -35.101 111.492 5.950 1.00 25.18 ? 128 SER B C 1 ATOM 4395 O O . SER C 1 76 ? -35.582 112.077 4.979 1.00 32.98 ? 128 SER B O 1 ATOM 4396 C CB . SER C 1 76 ? -37.225 110.632 6.995 1.00 35.84 ? 128 SER B CB 1 ATOM 4397 O OG . SER C 1 76 ? -37.215 111.692 7.935 1.00 38.47 ? 128 SER B OG 1 ATOM 4398 N N . ALA C 1 77 ? -33.965 111.869 6.531 1.00 27.44 ? 129 ALA B N 1 ATOM 4399 C CA . ALA C 1 77 ? -33.179 112.978 6.003 1.00 27.64 ? 129 ALA B CA 1 ATOM 4400 C C . ALA C 1 77 ? -32.362 112.516 4.806 1.00 28.40 ? 129 ALA B C 1 ATOM 4401 O O . ALA C 1 77 ? -31.655 111.513 4.869 1.00 28.54 ? 129 ALA B O 1 ATOM 4402 C CB . ALA C 1 77 ? -32.274 113.552 7.067 1.00 26.10 ? 129 ALA B CB 1 ATOM 4403 N N . LYS C 1 78 ? -32.482 113.254 3.713 1.00 22.61 ? 130 LYS B N 1 ATOM 4404 C CA . LYS C 1 78 ? -31.720 112.985 2.509 1.00 21.13 ? 130 LYS B CA 1 ATOM 4405 C C . LYS C 1 78 ? -30.376 113.707 2.612 1.00 21.47 ? 130 LYS B C 1 ATOM 4406 O O . LYS C 1 78 ? -30.324 114.904 2.869 1.00 21.74 ? 130 LYS B O 1 ATOM 4407 C CB . LYS C 1 78 ? -32.512 113.447 1.285 1.00 22.72 ? 130 LYS B CB 1 ATOM 4408 C CG . LYS C 1 78 ? -32.146 112.810 -0.039 1.00 35.58 ? 130 LYS B CG 1 ATOM 4409 C CD . LYS C 1 78 ? -32.850 113.559 -1.172 1.00 41.84 ? 130 LYS B CD 1 ATOM 4410 C CE . LYS C 1 78 ? -32.759 112.838 -2.504 1.00 47.97 ? 130 LYS B CE 1 ATOM 4411 N NZ . LYS C 1 78 ? -33.991 112.043 -2.775 1.00 54.69 ? 130 LYS B NZ 1 ATOM 4412 N N . ILE C 1 79 ? -29.291 112.958 2.460 1.00 19.20 ? 131 ILE B N 1 ATOM 4413 C CA . ILE C 1 79 ? -27.961 113.538 2.321 1.00 19.26 ? 131 ILE B CA 1 ATOM 4414 C C . ILE C 1 79 ? -27.396 112.962 1.033 1.00 15.54 ? 131 ILE B C 1 ATOM 4415 O O . ILE C 1 79 ? -27.537 111.767 0.789 1.00 16.81 ? 131 ILE B O 1 ATOM 4416 C CB . ILE C 1 79 ? -27.031 113.209 3.505 1.00 20.15 ? 131 ILE B CB 1 ATOM 4417 C CG1 . ILE C 1 79 ? -27.765 113.398 4.843 1.00 24.83 ? 131 ILE B CG1 1 ATOM 4418 C CG2 . ILE C 1 79 ? -25.781 114.065 3.420 1.00 21.23 ? 131 ILE B CG2 1 ATOM 4419 C CD1 . ILE C 1 79 ? -26.909 113.117 6.069 1.00 28.62 ? 131 ILE B CD1 1 ATOM 4420 N N . ASP C 1 80 ? -26.776 113.796 0.202 1.00 14.69 ? 132 ASP B N 1 ATOM 4421 C CA . ASP C 1 80 ? -26.364 113.354 -1.128 1.00 14.11 ? 132 ASP B CA 1 ATOM 4422 C C . ASP C 1 80 ? -25.443 112.130 -1.065 1.00 14.30 ? 132 ASP B C 1 ATOM 4423 O O . ASP C 1 80 ? -25.522 111.250 -1.920 1.00 15.19 ? 132 ASP B O 1 ATOM 4424 C CB . ASP C 1 80 ? -25.698 114.503 -1.907 1.00 14.15 ? 132 ASP B CB 1 ATOM 4425 C CG . ASP C 1 80 ? -24.453 115.058 -1.227 1.00 15.28 ? 132 ASP B CG 1 ATOM 4426 O OD1 . ASP C 1 80 ? -24.587 115.800 -0.230 1.00 13.77 ? 132 ASP B OD1 1 ATOM 4427 O OD2 . ASP C 1 80 ? -23.332 114.787 -1.720 1.00 14.48 ? 132 ASP B OD2 1 ATOM 4428 N N . THR C 1 81 ? -24.601 112.053 -0.041 1.00 13.35 ? 133 THR B N 1 ATOM 4429 C CA . THR C 1 81 ? -23.662 110.939 0.088 1.00 12.42 ? 133 THR B CA 1 ATOM 4430 C C . THR C 1 81 ? -24.339 109.590 0.370 1.00 13.64 ? 133 THR B C 1 ATOM 4431 O O . THR C 1 81 ? -23.751 108.536 0.121 1.00 14.76 ? 133 THR B O 1 ATOM 4432 C CB . THR C 1 81 ? -22.626 111.218 1.194 1.00 11.65 ? 133 THR B CB 1 ATOM 4433 O OG1 . THR C 1 81 ? -23.296 111.730 2.351 1.00 14.36 ? 133 THR B OG1 1 ATOM 4434 C CG2 . THR C 1 81 ? -21.589 112.230 0.713 1.00 13.49 ? 133 THR B CG2 1 ATOM 4435 N N . LYS C 1 82 ? -25.565 109.605 0.882 1.00 13.46 ? 134 LYS B N 1 ATOM 4436 C CA . LYS C 1 82 ? -26.288 108.354 1.101 1.00 15.70 ? 134 LYS B CA 1 ATOM 4437 C C . LYS C 1 82 ? -26.459 107.599 -0.217 1.00 17.80 ? 134 LYS B C 1 ATOM 4438 O O . LYS C 1 82 ? -26.322 106.373 -0.259 1.00 20.87 ? 134 LYS B O 1 ATOM 4439 C CB . LYS C 1 82 ? -27.652 108.621 1.743 1.00 16.61 ? 134 LYS B CB 1 ATOM 4440 C CG . LYS C 1 82 ? -27.599 109.056 3.196 1.00 20.11 ? 134 LYS B CG 1 ATOM 4441 C CD . LYS C 1 82 ? -29.018 109.184 3.751 1.00 24.01 ? 134 LYS B CD 1 ATOM 4442 C CE . LYS C 1 82 ? -29.035 109.445 5.237 1.00 36.52 ? 134 LYS B CE 1 ATOM 4443 N NZ . LYS C 1 82 ? -30.426 109.349 5.780 1.00 37.70 ? 134 LYS B NZ 1 ATOM 4444 N N . THR C 1 83 ? -26.724 108.318 -1.304 1.00 16.52 ? 135 THR B N 1 ATOM 4445 C CA . THR C 1 83 ? -26.916 107.653 -2.590 1.00 16.93 ? 135 THR B CA 1 ATOM 4446 C C . THR C 1 83 ? -25.615 107.508 -3.392 1.00 16.50 ? 135 THR B C 1 ATOM 4447 O O . THR C 1 83 ? -25.435 106.510 -4.085 1.00 18.66 ? 135 THR B O 1 ATOM 4448 C CB . THR C 1 83 ? -27.966 108.381 -3.446 1.00 24.15 ? 135 THR B CB 1 ATOM 4449 O OG1 . THR C 1 83 ? -27.684 109.778 -3.484 1.00 32.30 ? 135 THR B OG1 1 ATOM 4450 C CG2 . THR C 1 83 ? -29.345 108.168 -2.849 1.00 26.23 ? 135 THR B CG2 1 ATOM 4451 N N . THR C 1 84 ? -24.700 108.468 -3.284 1.00 13.50 ? 136 THR B N 1 ATOM 4452 C CA . THR C 1 84 ? -23.463 108.410 -4.066 1.00 11.81 ? 136 THR B CA 1 ATOM 4453 C C . THR C 1 84 ? -22.370 107.558 -3.426 1.00 13.63 ? 136 THR B C 1 ATOM 4454 O O . THR C 1 84 ? -21.521 107.019 -4.137 1.00 13.78 ? 136 THR B O 1 ATOM 4455 C CB . THR C 1 84 ? -22.861 109.803 -4.295 1.00 12.18 ? 136 THR B CB 1 ATOM 4456 O OG1 . THR C 1 84 ? -22.589 110.408 -3.029 1.00 13.33 ? 136 THR B OG1 1 ATOM 4457 C CG2 . THR C 1 84 ? -23.793 110.690 -5.114 1.00 12.22 ? 136 THR B CG2 1 ATOM 4458 N N . VAL C 1 85 ? -22.377 107.457 -2.095 1.00 12.38 ? 137 VAL B N 1 ATOM 4459 C CA . VAL C 1 85 ? -21.339 106.717 -1.372 1.00 14.40 ? 137 VAL B CA 1 ATOM 4460 C C . VAL C 1 85 ? -21.911 105.540 -0.580 1.00 17.08 ? 137 VAL B C 1 ATOM 4461 O O . VAL C 1 85 ? -21.244 104.518 -0.435 1.00 22.25 ? 137 VAL B O 1 ATOM 4462 C CB . VAL C 1 85 ? -20.560 107.650 -0.421 1.00 13.90 ? 137 VAL B CB 1 ATOM 4463 C CG1 . VAL C 1 85 ? -19.373 106.916 0.236 1.00 14.37 ? 137 VAL B CG1 1 ATOM 4464 C CG2 . VAL C 1 85 ? -20.077 108.880 -1.183 1.00 13.04 ? 137 VAL B CG2 1 ATOM 4465 N N . GLY C 1 86 ? -23.135 105.671 -0.081 1.00 14.68 ? 138 GLY B N 1 ATOM 4466 C CA . GLY C 1 86 ? -23.796 104.578 0.618 1.00 15.16 ? 138 GLY B CA 1 ATOM 4467 C C . GLY C 1 86 ? -23.825 104.738 2.130 1.00 20.67 ? 138 GLY B C 1 ATOM 4468 O O . GLY C 1 86 ? -24.110 103.785 2.857 1.00 22.96 ? 138 GLY B O 1 ATOM 4469 N N . ALA C 1 87 ? -23.529 105.937 2.611 1.00 17.42 ? 139 ALA B N 1 ATOM 4470 C CA . ALA C 1 87 ? -23.541 106.215 4.044 1.00 18.67 ? 139 ALA B CA 1 ATOM 4471 C C . ALA C 1 87 ? -23.816 107.695 4.291 1.00 18.68 ? 139 ALA B C 1 ATOM 4472 O O . ALA C 1 87 ? -23.558 108.524 3.418 1.00 16.80 ? 139 ALA B O 1 ATOM 4473 C CB . ALA C 1 87 ? -22.217 105.806 4.672 1.00 21.03 ? 139 ALA B CB 1 ATOM 4474 N N . PRO C 1 88 ? -24.338 108.040 5.481 1.00 17.10 ? 140 PRO B N 1 ATOM 4475 C CA . PRO C 1 88 ? -24.610 109.453 5.764 1.00 18.13 ? 140 PRO B CA 1 ATOM 4476 C C . PRO C 1 88 ? -23.337 110.192 6.137 1.00 19.68 ? 140 PRO B C 1 ATOM 4477 O O . PRO C 1 88 ? -22.967 110.297 7.313 1.00 22.92 ? 140 PRO B O 1 ATOM 4478 C CB . PRO C 1 88 ? -25.600 109.396 6.929 1.00 19.08 ? 140 PRO B CB 1 ATOM 4479 C CG . PRO C 1 88 ? -25.281 108.132 7.628 1.00 24.16 ? 140 PRO B CG 1 ATOM 4480 C CD . PRO C 1 88 ? -24.780 107.162 6.582 1.00 22.12 ? 140 PRO B CD 1 ATOM 4481 N N . TYR C 1 89 ? -22.673 110.708 5.109 1.00 13.74 ? 141 TYR B N 1 ATOM 4482 C CA . TYR C 1 89 ? -21.379 111.351 5.264 1.00 13.31 ? 141 TYR B CA 1 ATOM 4483 C C . TYR C 1 89 ? -21.418 112.848 5.013 1.00 15.34 ? 141 TYR B C 1 ATOM 4484 O O . TYR C 1 89 ? -22.082 113.318 4.081 1.00 16.44 ? 141 TYR B O 1 ATOM 4485 C CB . TYR C 1 89 ? -20.364 110.747 4.295 1.00 13.04 ? 141 TYR B CB 1 ATOM 4486 C CG . TYR C 1 89 ? -19.788 109.389 4.641 1.00 14.54 ? 141 TYR B CG 1 ATOM 4487 C CD1 . TYR C 1 89 ? -19.632 108.964 5.956 1.00 13.59 ? 141 TYR B CD1 1 ATOM 4488 C CD2 . TYR C 1 89 ? -19.356 108.551 3.631 1.00 15.12 ? 141 TYR B CD2 1 ATOM 4489 C CE1 . TYR C 1 89 ? -19.071 107.725 6.239 1.00 17.48 ? 141 TYR B CE1 1 ATOM 4490 C CE2 . TYR C 1 89 ? -18.799 107.318 3.901 1.00 17.23 ? 141 TYR B CE2 1 ATOM 4491 C CZ . TYR C 1 89 ? -18.661 106.912 5.201 1.00 20.04 ? 141 TYR B CZ 1 ATOM 4492 O OH . TYR C 1 89 ? -18.101 105.680 5.445 1.00 24.44 ? 141 TYR B OH 1 ATOM 4493 N N . MET C 1 90 ? -20.672 113.582 5.829 1.00 13.58 ? 142 MET B N 1 ATOM 4494 C CA . MET C 1 90 ? -20.313 114.951 5.511 1.00 11.65 ? 142 MET B CA 1 ATOM 4495 C C . MET C 1 90 ? -18.866 115.007 5.005 1.00 12.36 ? 142 MET B C 1 ATOM 4496 O O . MET C 1 90 ? -18.037 114.151 5.331 1.00 12.04 ? 142 MET B O 1 ATOM 4497 C CB . MET C 1 90 ? -20.503 115.870 6.731 1.00 12.30 ? 142 MET B CB 1 ATOM 4498 C CG . MET C 1 90 ? -19.626 115.561 7.934 1.00 15.05 ? 142 MET B CG 1 ATOM 4499 S SD . MET C 1 90 ? -20.094 116.550 9.372 1.00 18.11 ? 142 MET B SD 1 ATOM 4500 C CE . MET C 1 90 ? -18.800 116.060 10.508 1.00 19.22 ? 142 MET B CE 1 ATOM 4501 N N . ALA C 1 91 ? -18.570 116.018 4.196 1.00 11.00 ? 143 ALA B N 1 ATOM 4502 C CA . ALA C 1 91 ? -17.214 116.251 3.724 1.00 10.82 ? 143 ALA B CA 1 ATOM 4503 C C . ALA C 1 91 ? -16.339 116.612 4.910 1.00 12.85 ? 143 ALA B C 1 ATOM 4504 O O . ALA C 1 91 ? -16.704 117.446 5.738 1.00 14.17 ? 143 ALA B O 1 ATOM 4505 C CB . ALA C 1 91 ? -17.185 117.354 2.662 1.00 11.54 ? 143 ALA B CB 1 ATOM 4506 N N . ALA C 1 92 ? -15.194 115.943 5.007 1.00 10.86 ? 144 ALA B N 1 ATOM 4507 C CA . ALA C 1 92 ? -14.341 116.033 6.185 1.00 12.21 ? 144 ALA B CA 1 ATOM 4508 C C . ALA C 1 92 ? -12.875 116.231 5.820 1.00 12.24 ? 144 ALA B C 1 ATOM 4509 O O . ALA C 1 92 ? -12.451 115.908 4.707 1.00 11.69 ? 144 ALA B O 1 ATOM 4510 C CB . ALA C 1 92 ? -14.484 114.788 7.017 1.00 13.58 ? 144 ALA B CB 1 ATOM 4511 N N . GLY C 1 93 ? -12.106 116.735 6.787 1.00 11.44 ? 145 GLY B N 1 ATOM 4512 C CA . GLY C 1 93 ? -10.685 116.978 6.618 1.00 12.30 ? 145 GLY B CA 1 ATOM 4513 C C . GLY C 1 93 ? -10.307 118.356 7.114 1.00 14.45 ? 145 GLY B C 1 ATOM 4514 O O . GLY C 1 93 ? -10.725 119.356 6.534 1.00 14.80 ? 145 GLY B O 1 ATOM 4515 N N . ALA C 1 94 ? -9.491 118.414 8.161 1.00 13.47 ? 146 ALA B N 1 ATOM 4516 C CA . ALA C 1 94 ? -9.246 119.679 8.851 1.00 13.36 ? 146 ALA B CA 1 ATOM 4517 C C . ALA C 1 94 ? -8.324 120.641 8.101 1.00 12.87 ? 146 ALA B C 1 ATOM 4518 O O . ALA C 1 94 ? -8.352 121.845 8.368 1.00 12.68 ? 146 ALA B O 1 ATOM 4519 C CB . ALA C 1 94 ? -8.677 119.410 10.233 1.00 15.47 ? 146 ALA B CB 1 ATOM 4520 N N . CYS C 1 95 ? -7.498 120.136 7.189 1.00 11.56 ? 147 CYS B N 1 ATOM 4521 C CA . CYS C 1 95 ? -6.580 120.990 6.443 1.00 11.36 ? 147 CYS B CA 1 ATOM 4522 C C . CYS C 1 95 ? -7.185 121.475 5.136 1.00 12.52 ? 147 CYS B C 1 ATOM 4523 O O . CYS C 1 95 ? -7.778 120.690 4.403 1.00 11.83 ? 147 CYS B O 1 ATOM 4524 C CB . CYS C 1 95 ? -5.282 120.265 6.123 1.00 11.49 ? 147 CYS B CB 1 ATOM 4525 S SG . CYS C 1 95 ? -4.302 119.821 7.570 1.00 15.09 ? 147 CYS B SG 1 ATOM 4526 N N . PRO C 1 96 ? -7.026 122.771 4.826 1.00 11.88 ? 148 PRO B N 1 ATOM 4527 C CA . PRO C 1 96 ? -7.412 123.243 3.492 1.00 12.76 ? 148 PRO B CA 1 ATOM 4528 C C . PRO C 1 96 ? -6.654 122.481 2.412 1.00 11.52 ? 148 PRO B C 1 ATOM 4529 O O . PRO C 1 96 ? -5.471 122.194 2.561 1.00 11.35 ? 148 PRO B O 1 ATOM 4530 C CB . PRO C 1 96 ? -7.032 124.727 3.519 1.00 14.66 ? 148 PRO B CB 1 ATOM 4531 C CG . PRO C 1 96 ? -7.014 125.089 4.981 1.00 14.44 ? 148 PRO B CG 1 ATOM 4532 C CD . PRO C 1 96 ? -6.477 123.862 5.654 1.00 13.37 ? 148 PRO B CD 1 ATOM 4533 N N . ASN C 1 97 ? -7.354 122.146 1.336 1.00 12.00 ? 149 ASN B N 1 ATOM 4534 C CA . ASN C 1 97 ? -6.766 121.368 0.263 1.00 9.67 ? 149 ASN B CA 1 ATOM 4535 C C . ASN C 1 97 ? -6.555 122.249 -0.958 1.00 11.10 ? 149 ASN B C 1 ATOM 4536 O O . ASN C 1 97 ? -7.493 122.557 -1.686 1.00 11.82 ? 149 ASN B O 1 ATOM 4537 C CB . ASN C 1 97 ? -7.661 120.174 -0.054 1.00 12.75 ? 149 ASN B CB 1 ATOM 4538 C CG . ASN C 1 97 ? -6.922 119.056 -0.755 1.00 10.45 ? 149 ASN B CG 1 ATOM 4539 O OD1 . ASN C 1 97 ? -5.954 119.280 -1.478 1.00 10.69 ? 149 ASN B OD1 1 ATOM 4540 N ND2 . ASN C 1 97 ? -7.402 117.833 -0.560 1.00 11.53 ? 149 ASN B ND2 1 ATOM 4541 N N . TYR C 1 98 ? -5.316 122.677 -1.155 1.00 10.25 ? 150 TYR B N 1 ATOM 4542 C CA . TYR C 1 98 ? -5.009 123.669 -2.169 1.00 11.53 ? 150 TYR B CA 1 ATOM 4543 C C . TYR C 1 98 ? -4.999 123.056 -3.560 1.00 12.93 ? 150 TYR B C 1 ATOM 4544 O O . TYR C 1 98 ? -4.350 122.033 -3.807 1.00 12.56 ? 150 TYR B O 1 ATOM 4545 C CB . TYR C 1 98 ? -3.673 124.340 -1.854 1.00 9.96 ? 150 TYR B CB 1 ATOM 4546 C CG . TYR C 1 98 ? -3.724 125.116 -0.562 1.00 12.09 ? 150 TYR B CG 1 ATOM 4547 C CD1 . TYR C 1 98 ? -4.316 126.374 -0.517 1.00 12.08 ? 150 TYR B CD1 1 ATOM 4548 C CD2 . TYR C 1 98 ? -3.211 124.593 0.618 1.00 11.19 ? 150 TYR B CD2 1 ATOM 4549 C CE1 . TYR C 1 98 ? -4.388 127.087 0.661 1.00 13.34 ? 150 TYR B CE1 1 ATOM 4550 C CE2 . TYR C 1 98 ? -3.286 125.304 1.804 1.00 13.02 ? 150 TYR B CE2 1 ATOM 4551 C CZ . TYR C 1 98 ? -3.877 126.548 1.812 1.00 14.36 ? 150 TYR B CZ 1 ATOM 4552 O OH . TYR C 1 98 ? -3.958 127.263 2.981 1.00 16.27 ? 150 TYR B OH 1 ATOM 4553 N N . GLY C 1 99 ? -5.754 123.687 -4.452 1.00 12.34 ? 151 GLY B N 1 ATOM 4554 C CA . GLY C 1 99 ? -5.839 123.268 -5.837 1.00 12.37 ? 151 GLY B CA 1 ATOM 4555 C C . GLY C 1 99 ? -7.006 122.354 -6.128 1.00 12.12 ? 151 GLY B C 1 ATOM 4556 O O . GLY C 1 99 ? -7.339 122.152 -7.292 1.00 11.93 ? 151 GLY B O 1 ATOM 4557 N N . LYS C 1 100 ? -7.610 121.794 -5.083 1.00 10.73 ? 152 LYS B N 1 ATOM 4558 C CA . LYS C 1 100 ? -8.661 120.788 -5.238 1.00 10.63 ? 152 LYS B CA 1 ATOM 4559 C C . LYS C 1 100 ? -9.976 121.402 -5.705 1.00 11.64 ? 152 LYS B C 1 ATOM 4560 O O . LYS C 1 100 ? -10.557 122.232 -5.010 1.00 12.31 ? 152 LYS B O 1 ATOM 4561 C CB . LYS C 1 100 ? -8.880 120.038 -3.918 1.00 11.58 ? 152 LYS B CB 1 ATOM 4562 C CG . LYS C 1 100 ? -10.054 119.048 -3.923 1.00 9.83 ? 152 LYS B CG 1 ATOM 4563 C CD . LYS C 1 100 ? -10.086 118.226 -2.638 1.00 10.55 ? 152 LYS B CD 1 ATOM 4564 C CE . LYS C 1 100 ? -11.366 117.430 -2.465 1.00 10.61 ? 152 LYS B CE 1 ATOM 4565 N NZ . LYS C 1 100 ? -11.194 116.557 -1.284 1.00 10.52 ? 152 LYS B NZ 1 ATOM 4566 N N . VAL C 1 101 ? -10.444 120.952 -6.866 1.00 10.20 ? 153 VAL B N 1 ATOM 4567 C CA . VAL C 1 101 ? -11.699 121.386 -7.460 1.00 11.38 ? 153 VAL B CA 1 ATOM 4568 C C . VAL C 1 101 ? -12.537 120.146 -7.773 1.00 10.65 ? 153 VAL B C 1 ATOM 4569 O O . VAL C 1 101 ? -11.984 119.133 -8.221 1.00 11.28 ? 153 VAL B O 1 ATOM 4570 C CB . VAL C 1 101 ? -11.436 122.185 -8.748 1.00 12.95 ? 153 VAL B CB 1 ATOM 4571 C CG1 . VAL C 1 101 ? -12.718 122.489 -9.477 1.00 15.72 ? 153 VAL B CG1 1 ATOM 4572 C CG2 . VAL C 1 101 ? -10.688 123.467 -8.431 1.00 13.36 ? 153 VAL B CG2 1 ATOM 4573 N N . ILE C 1 102 ? -13.848 120.213 -7.564 1.00 9.84 ? 154 ILE B N 1 ATOM 4574 C CA . ILE C 1 102 ? -14.731 119.121 -7.969 1.00 10.43 ? 154 ILE B CA 1 ATOM 4575 C C . ILE C 1 102 ? -15.071 119.317 -9.445 1.00 12.62 ? 154 ILE B C 1 ATOM 4576 O O . ILE C 1 102 ? -15.798 120.237 -9.811 1.00 11.72 ? 154 ILE B O 1 ATOM 4577 C CB . ILE C 1 102 ? -16.010 119.048 -7.104 1.00 11.40 ? 154 ILE B CB 1 ATOM 4578 C CG1 . ILE C 1 102 ? -15.649 119.012 -5.610 1.00 10.25 ? 154 ILE B CG1 1 ATOM 4579 C CG2 . ILE C 1 102 ? -16.852 117.836 -7.492 1.00 13.93 ? 154 ILE B CG2 1 ATOM 4580 C CD1 . ILE C 1 102 ? -14.692 117.896 -5.219 1.00 12.81 ? 154 ILE B CD1 1 ATOM 4581 N N . ALA C 1 103 ? -14.493 118.460 -10.284 1.00 10.35 ? 155 ALA B N 1 ATOM 4582 C CA . ALA C 1 103 ? -14.659 118.539 -11.733 1.00 9.70 ? 155 ALA B CA 1 ATOM 4583 C C . ALA C 1 103 ? -15.808 117.671 -12.191 1.00 11.62 ? 155 ALA B C 1 ATOM 4584 O O . ALA C 1 103 ? -16.008 116.571 -11.677 1.00 11.80 ? 155 ALA B O 1 ATOM 4585 C CB . ALA C 1 103 ? -13.372 118.112 -12.437 1.00 11.55 ? 155 ALA B CB 1 ATOM 4586 N N . PHE C 1 104 ? -16.568 118.182 -13.148 1.00 10.20 ? 156 PHE B N 1 ATOM 4587 C CA . PHE C 1 104 ? -17.553 117.385 -13.868 1.00 10.96 ? 156 PHE B CA 1 ATOM 4588 C C . PHE C 1 104 ? -16.843 116.695 -15.015 1.00 12.31 ? 156 PHE B C 1 ATOM 4589 O O . PHE C 1 104 ? -16.106 117.334 -15.754 1.00 11.77 ? 156 PHE B O 1 ATOM 4590 C CB . PHE C 1 104 ? -18.697 118.262 -14.383 1.00 10.63 ? 156 PHE B CB 1 ATOM 4591 C CG . PHE C 1 104 ? -19.692 118.638 -13.318 1.00 10.31 ? 156 PHE B CG 1 ATOM 4592 C CD1 . PHE C 1 104 ? -19.291 119.357 -12.202 1.00 11.92 ? 156 PHE B CD1 1 ATOM 4593 C CD2 . PHE C 1 104 ? -21.023 118.270 -13.432 1.00 11.40 ? 156 PHE B CD2 1 ATOM 4594 C CE1 . PHE C 1 104 ? -20.193 119.694 -11.217 1.00 11.78 ? 156 PHE B CE1 1 ATOM 4595 C CE2 . PHE C 1 104 ? -21.937 118.608 -12.449 1.00 13.33 ? 156 PHE B CE2 1 ATOM 4596 C CZ . PHE C 1 104 ? -21.515 119.326 -11.338 1.00 11.59 ? 156 PHE B CZ 1 ATOM 4597 N N . THR C 1 105 ? -17.059 115.391 -15.160 1.00 11.94 ? 157 THR B N 1 ATOM 4598 C CA . THR C 1 105 ? -16.315 114.608 -16.135 1.00 11.97 ? 157 THR B CA 1 ATOM 4599 C C . THR C 1 105 ? -17.193 113.568 -16.819 1.00 10.88 ? 157 THR B C 1 ATOM 4600 O O . THR C 1 105 ? -18.335 113.331 -16.422 1.00 11.62 ? 157 THR B O 1 ATOM 4601 C CB . THR C 1 105 ? -15.117 113.867 -15.473 1.00 12.71 ? 157 THR B CB 1 ATOM 4602 O OG1 . THR C 1 105 ? -15.607 112.841 -14.604 1.00 13.91 ? 157 THR B OG1 1 ATOM 4603 C CG2 . THR C 1 105 ? -14.249 114.804 -14.676 1.00 12.99 ? 157 THR B CG2 1 ATOM 4604 N N . LYS C 1 106 ? -16.627 112.915 -17.829 1.00 12.41 ? 158 LYS B N 1 ATOM 4605 C CA . LYS C 1 106 ? -17.194 111.662 -18.301 1.00 13.38 ? 158 LYS B CA 1 ATOM 4606 C C . LYS C 1 106 ? -16.810 110.577 -17.284 1.00 12.96 ? 158 LYS B C 1 ATOM 4607 O O . LYS C 1 106 ? -16.013 110.823 -16.371 1.00 13.24 ? 158 LYS B O 1 ATOM 4608 C CB . LYS C 1 106 ? -16.705 111.325 -19.713 1.00 11.46 ? 158 LYS B CB 1 ATOM 4609 C CG . LYS C 1 106 ? -17.319 112.213 -20.800 1.00 15.35 ? 158 LYS B CG 1 ATOM 4610 C CD . LYS C 1 106 ? -16.740 111.871 -22.165 1.00 17.66 ? 158 LYS B CD 1 ATOM 4611 C CE . LYS C 1 106 ? -17.431 112.634 -23.287 1.00 19.16 ? 158 LYS B CE 1 ATOM 4612 N NZ . LYS C 1 106 ? -16.774 112.392 -24.605 1.00 22.05 ? 158 LYS B NZ 1 ATOM 4613 N N . ARG C 1 107 ? -17.390 109.390 -17.423 1.00 12.90 ? 159 ARG B N 1 ATOM 4614 C CA . ARG C 1 107 ? -17.188 108.348 -16.424 1.00 12.35 ? 159 ARG B CA 1 ATOM 4615 C C . ARG C 1 107 ? -15.718 107.925 -16.349 1.00 13.24 ? 159 ARG B C 1 ATOM 4616 O O . ARG C 1 107 ? -15.266 107.450 -15.302 1.00 13.79 ? 159 ARG B O 1 ATOM 4617 C CB . ARG C 1 107 ? -18.078 107.137 -16.713 1.00 14.74 ? 159 ARG B CB 1 ATOM 4618 C CG . ARG C 1 107 ? -18.186 106.159 -15.541 1.00 14.42 ? 159 ARG B CG 1 ATOM 4619 C CD . ARG C 1 107 ? -19.300 105.134 -15.740 1.00 16.56 ? 159 ARG B CD 1 ATOM 4620 N NE . ARG C 1 107 ? -20.593 105.801 -15.832 1.00 16.93 ? 159 ARG B NE 1 ATOM 4621 C CZ . ARG C 1 107 ? -21.372 105.835 -16.905 1.00 19.86 ? 159 ARG B CZ 1 ATOM 4622 N NH1 . ARG C 1 107 ? -21.043 105.200 -18.023 1.00 21.28 ? 159 ARG B NH1 1 ATOM 4623 N NH2 . ARG C 1 107 ? -22.511 106.505 -16.851 1.00 19.56 ? 159 ARG B NH2 1 ATOM 4624 N N . ASP C 1 108 ? -14.972 108.096 -17.443 1.00 12.10 ? 160 ASP B N 1 ATOM 4625 C CA . ASP C 1 108 ? -13.552 107.767 -17.451 1.00 11.84 ? 160 ASP B CA 1 ATOM 4626 C C . ASP C 1 108 ? -12.660 108.937 -17.058 1.00 13.74 ? 160 ASP B C 1 ATOM 4627 O O . ASP C 1 108 ? -11.447 108.854 -17.199 1.00 14.49 ? 160 ASP B O 1 ATOM 4628 C CB . ASP C 1 108 ? -13.120 107.240 -18.829 1.00 12.80 ? 160 ASP B CB 1 ATOM 4629 C CG . ASP C 1 108 ? -13.266 108.274 -19.942 1.00 18.31 ? 160 ASP B CG 1 ATOM 4630 O OD1 . ASP C 1 108 ? -13.688 109.425 -19.677 1.00 16.78 ? 160 ASP B OD1 1 ATOM 4631 O OD2 . ASP C 1 108 ? -12.943 107.929 -21.101 1.00 21.58 ? 160 ASP B OD2 1 ATOM 4632 N N . GLY C 1 109 ? -13.258 110.021 -16.564 1.00 11.46 ? 161 GLY B N 1 ATOM 4633 C CA . GLY C 1 109 ? -12.512 111.191 -16.130 1.00 14.32 ? 161 GLY B CA 1 ATOM 4634 C C . GLY C 1 109 ? -12.159 112.184 -17.225 1.00 13.57 ? 161 GLY B C 1 ATOM 4635 O O . GLY C 1 109 ? -11.595 113.248 -16.938 1.00 16.09 ? 161 GLY B O 1 ATOM 4636 N N . SER C 1 110 ? -12.492 111.858 -18.472 1.00 13.31 ? 162 SER B N 1 ATOM 4637 C CA . SER C 1 110 ? -12.137 112.713 -19.604 1.00 15.24 ? 162 SER B CA 1 ATOM 4638 C C . SER C 1 110 ? -13.172 113.835 -19.794 1.00 14.28 ? 162 SER B C 1 ATOM 4639 O O . SER C 1 110 ? -14.216 113.843 -19.147 1.00 13.21 ? 162 SER B O 1 ATOM 4640 C CB . SER C 1 110 ? -12.010 111.889 -20.888 1.00 16.64 ? 162 SER B CB 1 ATOM 4641 O OG . SER C 1 110 ? -13.278 111.497 -21.369 1.00 16.06 ? 162 SER B OG 1 ATOM 4642 N N . ARG C 1 111 ? -12.849 114.782 -20.676 1.00 14.97 ? 163 ARG B N 1 ATOM 4643 C CA . ARG C 1 111 ? -13.693 115.949 -20.982 1.00 16.43 ? 163 ARG B CA 1 ATOM 4644 C C . ARG C 1 111 ? -14.086 116.666 -19.702 1.00 14.56 ? 163 ARG B C 1 ATOM 4645 O O . ARG C 1 111 ? -15.249 117.053 -19.501 1.00 17.94 ? 163 ARG B O 1 ATOM 4646 C CB . ARG C 1 111 ? -14.944 115.553 -21.772 1.00 17.70 ? 163 ARG B CB 1 ATOM 4647 C CG . ARG C 1 111 ? -14.670 114.802 -23.064 1.00 29.65 ? 163 ARG B CG 1 ATOM 4648 C CD . ARG C 1 111 ? -13.852 115.603 -24.067 1.00 37.60 ? 163 ARG B CD 1 ATOM 4649 N NE . ARG C 1 111 ? -12.890 114.739 -24.756 1.00 47.08 ? 163 ARG B NE 1 ATOM 4650 C CZ . ARG C 1 111 ? -11.580 114.702 -24.514 1.00 36.10 ? 163 ARG B CZ 1 ATOM 4651 N NH1 . ARG C 1 111 ? -10.808 113.869 -25.198 1.00 51.65 ? 163 ARG B NH1 1 ATOM 4652 N NH2 . ARG C 1 111 ? -11.028 115.496 -23.604 1.00 44.46 ? 163 ARG B NH2 1 ATOM 4653 N N . SER C 1 112 ? -13.098 116.839 -18.836 1.00 14.52 ? 164 SER B N 1 ATOM 4654 C CA . SER C 1 112 ? -13.324 117.442 -17.535 1.00 13.24 ? 164 SER B CA 1 ATOM 4655 C C . SER C 1 112 ? -13.635 118.926 -17.659 1.00 16.13 ? 164 SER B C 1 ATOM 4656 O O . SER C 1 112 ? -13.117 119.618 -18.538 1.00 17.05 ? 164 SER B O 1 ATOM 4657 C CB . SER C 1 112 ? -12.115 117.235 -16.626 1.00 13.17 ? 164 SER B CB 1 ATOM 4658 O OG . SER C 1 112 ? -10.945 117.788 -17.193 1.00 18.32 ? 164 SER B OG 1 ATOM 4659 N N . ASP C 1 113 ? -14.493 119.386 -16.759 1.00 13.19 ? 165 ASP B N 1 ATOM 4660 C CA . ASP C 1 113 ? -14.903 120.783 -16.681 1.00 13.49 ? 165 ASP B CA 1 ATOM 4661 C C . ASP C 1 113 ? -14.683 121.240 -15.246 1.00 12.66 ? 165 ASP B C 1 ATOM 4662 O O . ASP C 1 113 ? -15.404 120.807 -14.351 1.00 12.39 ? 165 ASP B O 1 ATOM 4663 C CB . ASP C 1 113 ? -16.367 120.931 -17.097 1.00 13.80 ? 165 ASP B CB 1 ATOM 4664 C CG . ASP C 1 113 ? -16.832 122.374 -17.137 1.00 16.50 ? 165 ASP B CG 1 ATOM 4665 O OD1 . ASP C 1 113 ? -16.278 123.224 -16.411 1.00 16.87 ? 165 ASP B OD1 1 ATOM 4666 O OD2 . ASP C 1 113 ? -17.777 122.655 -17.900 1.00 18.94 ? 165 ASP B OD2 1 ATOM 4667 N N . MET C 1 114 ? -13.708 122.121 -15.038 1.00 13.31 ? 166 MET B N 1 ATOM 4668 C CA . MET C 1 114 ? -13.347 122.547 -13.691 1.00 14.98 ? 166 MET B CA 1 ATOM 4669 C C . MET C 1 114 ? -13.964 123.889 -13.277 1.00 14.17 ? 166 MET B C 1 ATOM 4670 O O . MET C 1 114 ? -13.585 124.439 -12.247 1.00 14.61 ? 166 MET B O 1 ATOM 4671 C CB . MET C 1 114 ? -11.824 122.584 -13.567 1.00 16.64 ? 166 MET B CB 1 ATOM 4672 C CG . MET C 1 114 ? -11.236 121.165 -13.457 1.00 20.12 ? 166 MET B CG 1 ATOM 4673 S SD . MET C 1 114 ? -9.467 121.120 -13.452 1.00 22.94 ? 166 MET B SD 1 ATOM 4674 C CE . MET C 1 114 ? -9.107 121.737 -11.806 1.00 16.06 ? 166 MET B CE 1 ATOM 4675 N N . THR C 1 115 ? -14.920 124.402 -14.053 1.00 13.72 ? 167 THR B N 1 ATOM 4676 C CA . THR C 1 115 ? -15.657 125.604 -13.637 1.00 13.37 ? 167 THR B CA 1 ATOM 4677 C C . THR C 1 115 ? -17.161 125.370 -13.510 1.00 14.60 ? 167 THR B C 1 ATOM 4678 O O . THR C 1 115 ? -17.875 126.198 -12.940 1.00 13.49 ? 167 THR B O 1 ATOM 4679 C CB . THR C 1 115 ? -15.411 126.785 -14.605 1.00 17.74 ? 167 THR B CB 1 ATOM 4680 O OG1 . THR C 1 115 ? -15.882 126.461 -15.913 1.00 20.59 ? 167 THR B OG1 1 ATOM 4681 C CG2 . THR C 1 115 ? -13.935 127.134 -14.657 1.00 19.92 ? 167 THR B CG2 1 ATOM 4682 N N . ARG C 1 116 ? -17.637 124.230 -14.000 1.00 12.10 ? 168 ARG B N 1 ATOM 4683 C CA . ARG C 1 116 ? -19.050 123.867 -13.933 1.00 12.70 ? 168 ARG B CA 1 ATOM 4684 C C . ARG C 1 116 ? -19.594 123.888 -12.495 1.00 11.98 ? 168 ARG B C 1 ATOM 4685 O O . ARG C 1 116 ? -20.782 124.155 -12.276 1.00 12.14 ? 168 ARG B O 1 ATOM 4686 C CB . ARG C 1 116 ? -19.234 122.484 -14.572 1.00 13.23 ? 168 ARG B CB 1 ATOM 4687 C CG . ARG C 1 116 ? -20.575 121.826 -14.402 1.00 17.76 ? 168 ARG B CG 1 ATOM 4688 C CD . ARG C 1 116 ? -21.649 122.366 -15.332 1.00 18.64 ? 168 ARG B CD 1 ATOM 4689 N NE . ARG C 1 116 ? -22.814 121.504 -15.185 1.00 16.90 ? 168 ARG B NE 1 ATOM 4690 C CZ . ARG C 1 116 ? -23.110 120.460 -15.957 1.00 16.23 ? 168 ARG B CZ 1 ATOM 4691 N NH1 . ARG C 1 116 ? -22.375 120.146 -17.024 1.00 18.29 ? 168 ARG B NH1 1 ATOM 4692 N NH2 . ARG C 1 116 ? -24.177 119.736 -15.663 1.00 14.99 ? 168 ARG B NH2 1 ATOM 4693 N N . TRP C 1 117 ? -18.737 123.585 -11.521 1.00 11.55 ? 169 TRP B N 1 ATOM 4694 C CA . TRP C 1 117 ? -19.158 123.522 -10.122 1.00 11.35 ? 169 TRP B CA 1 ATOM 4695 C C . TRP C 1 117 ? -19.778 124.837 -9.639 1.00 12.03 ? 169 TRP B C 1 ATOM 4696 O O . TRP C 1 117 ? -20.563 124.832 -8.691 1.00 11.67 ? 169 TRP B O 1 ATOM 4697 C CB . TRP C 1 117 ? -17.977 123.144 -9.212 1.00 10.78 ? 169 TRP B CB 1 ATOM 4698 C CG . TRP C 1 117 ? -16.929 124.200 -9.094 1.00 10.39 ? 169 TRP B CG 1 ATOM 4699 C CD1 . TRP C 1 117 ? -15.797 124.324 -9.845 1.00 11.55 ? 169 TRP B CD1 1 ATOM 4700 C CD2 . TRP C 1 117 ? -16.912 125.296 -8.162 1.00 9.79 ? 169 TRP B CD2 1 ATOM 4701 N NE1 . TRP C 1 117 ? -15.079 125.426 -9.442 1.00 12.81 ? 169 TRP B NE1 1 ATOM 4702 C CE2 . TRP C 1 117 ? -15.739 126.034 -8.407 1.00 11.54 ? 169 TRP B CE2 1 ATOM 4703 C CE3 . TRP C 1 117 ? -17.770 125.713 -7.141 1.00 13.10 ? 169 TRP B CE3 1 ATOM 4704 C CZ2 . TRP C 1 117 ? -15.409 127.178 -7.676 1.00 12.67 ? 169 TRP B CZ2 1 ATOM 4705 C CZ3 . TRP C 1 117 ? -17.436 126.847 -6.420 1.00 12.31 ? 169 TRP B CZ3 1 ATOM 4706 C CH2 . TRP C 1 117 ? -16.267 127.556 -6.688 1.00 11.97 ? 169 TRP B CH2 1 ATOM 4707 N N . LYS C 1 118 ? -19.445 125.946 -10.300 1.00 11.09 ? 170 LYS B N 1 ATOM 4708 C CA . LYS C 1 118 ? -19.915 127.267 -9.878 1.00 11.32 ? 170 LYS B CA 1 ATOM 4709 C C . LYS C 1 118 ? -21.409 127.474 -10.118 1.00 13.23 ? 170 LYS B C 1 ATOM 4710 O O . LYS C 1 118 ? -22.011 128.343 -9.487 1.00 12.17 ? 170 LYS B O 1 ATOM 4711 C CB . LYS C 1 118 ? -19.123 128.359 -10.594 1.00 11.74 ? 170 LYS B CB 1 ATOM 4712 C CG . LYS C 1 118 ? -17.652 128.363 -10.259 1.00 12.06 ? 170 LYS B CG 1 ATOM 4713 C CD . LYS C 1 118 ? -16.949 129.517 -10.939 1.00 16.06 ? 170 LYS B CD 1 ATOM 4714 C CE . LYS C 1 118 ? -15.476 129.513 -10.624 1.00 21.82 ? 170 LYS B CE 1 ATOM 4715 N NZ . LYS C 1 118 ? -14.819 130.758 -11.108 1.00 29.66 ? 170 LYS B NZ 1 ATOM 4716 N N . ASN C 1 119 ? -22.015 126.689 -11.012 1.00 10.00 ? 171 ASN B N 1 ATOM 4717 C CA . ASN C 1 119 ? -23.468 126.711 -11.170 1.00 11.16 ? 171 ASN B CA 1 ATOM 4718 C C . ASN C 1 119 ? -24.126 126.143 -9.918 1.00 12.24 ? 171 ASN B C 1 ATOM 4719 O O . ASN C 1 119 ? -23.569 125.250 -9.263 1.00 12.01 ? 171 ASN B O 1 ATOM 4720 C CB . ASN C 1 119 ? -23.929 125.897 -12.388 1.00 10.68 ? 171 ASN B CB 1 ATOM 4721 C CG . ASN C 1 119 ? -23.427 126.445 -13.713 1.00 15.08 ? 171 ASN B CG 1 ATOM 4722 O OD1 . ASN C 1 119 ? -22.710 127.443 -13.772 1.00 14.08 ? 171 ASN B OD1 1 ATOM 4723 N ND2 . ASN C 1 119 ? -23.812 125.771 -14.797 1.00 15.16 ? 171 ASN B ND2 1 ATOM 4724 N N . GLU C 1 120 ? -25.327 126.613 -9.588 1.00 13.06 ? 172 GLU B N 1 ATOM 4725 C CA . GLU C 1 120 ? -26.017 126.073 -8.430 1.00 10.45 ? 172 GLU B CA 1 ATOM 4726 C C . GLU C 1 120 ? -26.469 124.631 -8.629 1.00 11.58 ? 172 GLU B C 1 ATOM 4727 O O . GLU C 1 120 ? -26.599 124.131 -9.759 1.00 12.53 ? 172 GLU B O 1 ATOM 4728 C CB . GLU C 1 120 ? -27.234 126.931 -8.057 1.00 12.19 ? 172 GLU B CB 1 ATOM 4729 C CG . GLU C 1 120 ? -26.885 128.208 -7.331 1.00 13.40 ? 172 GLU B CG 1 ATOM 4730 C CD . GLU C 1 120 ? -28.108 128.951 -6.824 1.00 12.56 ? 172 GLU B CD 1 ATOM 4731 O OE1 . GLU C 1 120 ? -29.226 128.413 -6.936 1.00 14.71 ? 172 GLU B OE1 1 ATOM 4732 O OE2 . GLU C 1 120 ? -27.941 130.071 -6.316 1.00 15.38 ? 172 GLU B OE2 1 ATOM 4733 N N . ILE C 1 121 ? -26.725 123.963 -7.507 1.00 11.70 ? 173 ILE B N 1 ATOM 4734 C CA . ILE C 1 121 ? -27.288 122.619 -7.504 1.00 12.91 ? 173 ILE B CA 1 ATOM 4735 C C . ILE C 1 121 ? -28.766 122.587 -7.916 1.00 12.77 ? 173 ILE B C 1 ATOM 4736 O O . ILE C 1 121 ? -29.456 123.620 -7.917 1.00 14.21 ? 173 ILE B O 1 ATOM 4737 C CB . ILE C 1 121 ? -27.152 121.960 -6.103 1.00 13.14 ? 173 ILE B CB 1 ATOM 4738 C CG1 . ILE C 1 121 ? -27.957 122.743 -5.049 1.00 14.09 ? 173 ILE B CG1 1 ATOM 4739 C CG2 . ILE C 1 121 ? -25.687 121.854 -5.703 1.00 13.37 ? 173 ILE B CG2 1 ATOM 4740 C CD1 . ILE C 1 121 ? -27.996 122.090 -3.666 1.00 14.64 ? 173 ILE B CD1 1 ATOM 4741 N N . HIS C 1 122 ? -29.236 121.387 -8.241 1.00 13.45 ? 174 HIS B N 1 ATOM 4742 C CA . HIS C 1 122 ? -30.645 121.114 -8.497 1.00 13.44 ? 174 HIS B CA 1 ATOM 4743 C C . HIS C 1 122 ? -31.078 119.956 -7.597 1.00 14.06 ? 174 HIS B C 1 ATOM 4744 O O . HIS C 1 122 ? -31.267 118.834 -8.055 1.00 15.92 ? 174 HIS B O 1 ATOM 4745 C CB . HIS C 1 122 ? -30.898 120.781 -9.978 1.00 14.69 ? 174 HIS B CB 1 ATOM 4746 C CG . HIS C 1 122 ? -32.354 120.713 -10.335 1.00 14.20 ? 174 HIS B CG 1 ATOM 4747 N ND1 . HIS C 1 122 ? -32.959 121.617 -11.183 1.00 17.04 ? 174 HIS B ND1 1 ATOM 4748 C CD2 . HIS C 1 122 ? -33.334 119.867 -9.931 1.00 18.39 ? 174 HIS B CD2 1 ATOM 4749 C CE1 . HIS C 1 122 ? -34.244 121.327 -11.291 1.00 18.04 ? 174 HIS B CE1 1 ATOM 4750 N NE2 . HIS C 1 122 ? -34.498 120.270 -10.543 1.00 17.47 ? 174 HIS B NE2 1 ATOM 4751 N N . ALA C 1 123 ? -31.245 120.243 -6.311 1.00 14.37 ? 175 ALA B N 1 ATOM 4752 C CA . ALA C 1 123 ? -31.562 119.204 -5.333 1.00 15.74 ? 175 ALA B CA 1 ATOM 4753 C C . ALA C 1 123 ? -33.063 119.095 -5.060 1.00 18.75 ? 175 ALA B C 1 ATOM 4754 O O . ALA C 1 123 ? -33.479 118.416 -4.121 1.00 19.55 ? 175 ALA B O 1 ATOM 4755 C CB . ALA C 1 123 ? -30.813 119.466 -4.038 1.00 17.43 ? 175 ALA B CB 1 ATOM 4756 N N . ASN C 1 124 ? -33.861 119.756 -5.894 1.00 16.45 ? 176 ASN B N 1 ATOM 4757 C CA . ASN C 1 124 ? -35.319 119.725 -5.789 1.00 16.90 ? 176 ASN B CA 1 ATOM 4758 C C . ASN C 1 124 ? -35.789 120.322 -4.465 1.00 19.31 ? 176 ASN B C 1 ATOM 4759 O O . ASN C 1 124 ? -36.559 119.705 -3.721 1.00 23.20 ? 176 ASN B O 1 ATOM 4760 C CB . ASN C 1 124 ? -35.834 118.296 -5.962 1.00 18.84 ? 176 ASN B CB 1 ATOM 4761 C CG . ASN C 1 124 ? -35.324 117.647 -7.236 1.00 23.24 ? 176 ASN B CG 1 ATOM 4762 O OD1 . ASN C 1 124 ? -34.692 116.591 -7.197 1.00 32.11 ? 176 ASN B OD1 1 ATOM 4763 N ND2 . ASN C 1 124 ? -35.580 118.287 -8.368 1.00 23.93 ? 176 ASN B ND2 1 ATOM 4764 N N . VAL C 1 125 ? -35.334 121.544 -4.207 1.00 16.83 ? 177 VAL B N 1 ATOM 4765 C CA . VAL C 1 125 ? -35.604 122.251 -2.959 1.00 16.64 ? 177 VAL B CA 1 ATOM 4766 C C . VAL C 1 125 ? -36.427 123.521 -3.195 1.00 19.03 ? 177 VAL B C 1 ATOM 4767 O O . VAL C 1 125 ? -37.412 123.747 -2.500 1.00 17.99 ? 177 VAL B O 1 ATOM 4768 C CB . VAL C 1 125 ? -34.281 122.610 -2.233 1.00 16.22 ? 177 VAL B CB 1 ATOM 4769 C CG1 . VAL C 1 125 ? -34.524 123.504 -1.020 1.00 17.88 ? 177 VAL B CG1 1 ATOM 4770 C CG2 . VAL C 1 125 ? -33.563 121.334 -1.810 1.00 17.52 ? 177 VAL B CG2 1 ATOM 4771 N N . MET C 1 126 ? -36.037 124.330 -4.179 1.00 17.01 ? 178 MET B N 1 ATOM 4772 C CA . MET C 1 126 ? -36.662 125.641 -4.406 1.00 16.16 ? 178 MET B CA 1 ATOM 4773 C C . MET C 1 126 ? -37.694 125.602 -5.539 1.00 17.05 ? 178 MET B C 1 ATOM 4774 O O . MET C 1 126 ? -37.394 125.107 -6.624 1.00 17.34 ? 178 MET B O 1 ATOM 4775 C CB . MET C 1 126 ? -35.585 126.683 -4.731 1.00 16.24 ? 178 MET B CB 1 ATOM 4776 C CG . MET C 1 126 ? -34.473 126.778 -3.695 1.00 16.75 ? 178 MET B CG 1 ATOM 4777 S SD . MET C 1 126 ? -35.074 127.248 -2.060 1.00 18.51 ? 178 MET B SD 1 ATOM 4778 C CE . MET C 1 126 ? -33.513 127.412 -1.205 1.00 17.83 ? 178 MET B CE 1 ATOM 4779 N N . PRO C 1 127 ? -38.915 126.136 -5.309 1.00 17.58 ? 179 PRO B N 1 ATOM 4780 C CA . PRO C 1 127 ? -39.410 126.810 -4.103 1.00 18.88 ? 179 PRO B CA 1 ATOM 4781 C C . PRO C 1 127 ? -39.754 125.822 -3.000 1.00 15.78 ? 179 PRO B C 1 ATOM 4782 O O . PRO C 1 127 ? -40.381 124.795 -3.267 1.00 18.13 ? 179 PRO B O 1 ATOM 4783 C CB . PRO C 1 127 ? -40.673 127.531 -4.598 1.00 16.87 ? 179 PRO B CB 1 ATOM 4784 C CG . PRO C 1 127 ? -41.188 126.645 -5.674 1.00 18.07 ? 179 PRO B CG 1 ATOM 4785 C CD . PRO C 1 127 ? -39.937 126.125 -6.373 1.00 16.94 ? 179 PRO B CD 1 ATOM 4786 N N . HIS C 1 128 ? -39.351 126.140 -1.776 1.00 18.45 ? 180 HIS B N 1 ATOM 4787 C CA . HIS C 1 128 ? -39.641 125.275 -0.641 1.00 21.69 ? 180 HIS B CA 1 ATOM 4788 C C . HIS C 1 128 ? -41.115 125.380 -0.256 1.00 22.80 ? 180 HIS B C 1 ATOM 4789 O O . HIS C 1 128 ? -41.729 124.404 0.170 1.00 21.87 ? 180 HIS B O 1 ATOM 4790 C CB . HIS C 1 128 ? -38.759 125.636 0.550 1.00 19.56 ? 180 HIS B CB 1 ATOM 4791 C CG . HIS C 1 128 ? -38.968 124.745 1.733 1.00 22.16 ? 180 HIS B CG 1 ATOM 4792 N ND1 . HIS C 1 128 ? -38.657 123.402 1.716 1.00 25.06 ? 180 HIS B ND1 1 ATOM 4793 C CD2 . HIS C 1 128 ? -39.482 124.999 2.960 1.00 23.14 ? 180 HIS B CD2 1 ATOM 4794 C CE1 . HIS C 1 128 ? -38.960 122.869 2.887 1.00 27.12 ? 180 HIS B CE1 1 ATOM 4795 N NE2 . HIS C 1 128 ? -39.462 123.817 3.660 1.00 23.75 ? 180 HIS B NE2 1 ATOM 4796 N N . SER C 1 129 ? -41.669 126.576 -0.422 1.00 20.81 ? 181 SER B N 1 ATOM 4797 C CA . SER C 1 129 ? -43.071 126.843 -0.131 1.00 22.91 ? 181 SER B CA 1 ATOM 4798 C C . SER C 1 129 ? -43.634 127.784 -1.183 1.00 20.27 ? 181 SER B C 1 ATOM 4799 O O . SER C 1 129 ? -42.915 128.641 -1.683 1.00 19.11 ? 181 SER B O 1 ATOM 4800 C CB . SER C 1 129 ? -43.219 127.463 1.260 1.00 29.63 ? 181 SER B CB 1 ATOM 4801 O OG . SER C 1 129 ? -44.533 127.957 1.469 1.00 27.69 ? 181 SER B OG 1 ATOM 4802 N N . THR C 1 130 ? -44.909 127.615 -1.520 1.00 20.88 ? 182 THR B N 1 ATOM 4803 C CA . THR C 1 130 ? -45.605 128.592 -2.359 1.00 20.33 ? 182 THR B CA 1 ATOM 4804 C C . THR C 1 130 ? -46.877 129.067 -1.668 1.00 26.34 ? 182 THR B C 1 ATOM 4805 O O . THR C 1 130 ? -47.837 129.462 -2.326 1.00 22.93 ? 182 THR B O 1 ATOM 4806 C CB . THR C 1 130 ? -45.964 128.022 -3.749 1.00 21.83 ? 182 THR B CB 1 ATOM 4807 O OG1 . THR C 1 130 ? -46.743 126.827 -3.609 1.00 26.00 ? 182 THR B OG1 1 ATOM 4808 C CG2 . THR C 1 130 ? -44.701 127.725 -4.552 1.00 21.05 ? 182 THR B CG2 1 ATOM 4809 N N . THR C 1 131 ? -46.867 129.042 -0.340 1.00 21.58 ? 183 THR B N 1 ATOM 4810 C CA . THR C 1 131 ? -48.026 129.457 0.441 1.00 21.80 ? 183 THR B CA 1 ATOM 4811 C C . THR C 1 131 ? -48.428 130.889 0.099 1.00 22.36 ? 183 THR B C 1 ATOM 4812 O O . THR C 1 131 ? -47.591 131.789 0.094 1.00 22.44 ? 183 THR B O 1 ATOM 4813 C CB . THR C 1 131 ? -47.742 129.330 1.948 1.00 22.51 ? 183 THR B CB 1 ATOM 4814 O OG1 . THR C 1 131 ? -47.560 127.944 2.266 1.00 25.33 ? 183 THR B OG1 1 ATOM 4815 C CG2 . THR C 1 131 ? -48.897 129.892 2.789 1.00 27.12 ? 183 THR B CG2 1 ATOM 4816 N N . SER C 1 132 ? -49.716 131.050 -0.210 1.00 22.41 ? 184 SER B N 1 ATOM 4817 C CA . SER C 1 132 ? -50.364 132.336 -0.514 1.00 25.61 ? 184 SER B CA 1 ATOM 4818 C C . SER C 1 132 ? -50.101 132.803 -1.950 1.00 32.03 ? 184 SER B C 1 ATOM 4819 O O . SER C 1 132 ? -50.642 133.825 -2.378 1.00 27.37 ? 184 SER B O 1 ATOM 4820 C CB . SER C 1 132 ? -49.932 133.425 0.474 1.00 25.96 ? 184 SER B CB 1 ATOM 4821 O OG . SER C 1 132 ? -48.720 134.037 0.091 1.00 27.42 ? 184 SER B OG 1 ATOM 4822 N N . CYS C 1 133 ? -49.291 132.054 -2.697 1.00 27.76 ? 185 CYS B N 1 ATOM 4823 C CA . CYS C 1 133 ? -49.053 132.366 -4.108 1.00 24.69 ? 185 CYS B CA 1 ATOM 4824 C C . CYS C 1 133 ? -50.293 132.097 -4.951 1.00 25.62 ? 185 CYS B C 1 ATOM 4825 O O . CYS C 1 133 ? -51.085 131.206 -4.650 1.00 25.86 ? 185 CYS B O 1 ATOM 4826 C CB . CYS C 1 133 ? -47.881 131.553 -4.669 1.00 25.24 ? 185 CYS B CB 1 ATOM 4827 S SG . CYS C 1 133 ? -46.282 131.917 -3.924 1.00 22.68 ? 185 CYS B SG 1 ATOM 4828 N N . ALA C 1 134 ? -50.447 132.860 -6.028 1.00 33.30 ? 186 ALA B N 1 ATOM 4829 C CA . ALA C 1 134 ? -51.560 132.663 -6.946 1.00 28.09 ? 186 ALA B CA 1 ATOM 4830 C C . ALA C 1 134 ? -51.571 131.261 -7.547 1.00 31.67 ? 186 ALA B C 1 ATOM 4831 O O . ALA C 1 134 ? -52.631 130.659 -7.714 1.00 33.26 ? 186 ALA B O 1 ATOM 4832 C CB . ALA C 1 134 ? -51.515 133.706 -8.050 1.00 29.86 ? 186 ALA B CB 1 ATOM 4833 N N . SER C 1 135 ? -50.388 130.745 -7.879 1.00 30.41 ? 187 SER B N 1 ATOM 4834 C CA . SER C 1 135 ? -50.262 129.392 -8.409 1.00 33.93 ? 187 SER B CA 1 ATOM 4835 C C . SER C 1 135 ? -49.265 128.589 -7.589 1.00 20.53 ? 187 SER B C 1 ATOM 4836 O O . SER C 1 135 ? -48.472 129.151 -6.838 1.00 24.71 ? 187 SER B O 1 ATOM 4837 C CB . SER C 1 135 ? -49.829 129.420 -9.877 1.00 37.05 ? 187 SER B CB 1 ATOM 4838 O OG . SER C 1 135 ? -50.949 129.333 -10.741 1.00 35.09 ? 187 SER B OG 1 ATOM 4839 N N . ARG C 1 136 ? -49.317 127.273 -7.746 1.00 30.19 ? 188 ARG B N 1 ATOM 4840 C CA . ARG C 1 136 ? -48.441 126.382 -7.005 1.00 27.43 ? 188 ARG B CA 1 ATOM 4841 C C . ARG C 1 136 ? -47.319 125.860 -7.885 1.00 29.65 ? 188 ARG B C 1 ATOM 4842 O O . ARG C 1 136 ? -47.417 125.865 -9.111 1.00 30.00 ? 188 ARG B O 1 ATOM 4843 C CB . ARG C 1 136 ? -49.230 125.210 -6.426 1.00 40.30 ? 188 ARG B CB 1 ATOM 4844 C CG . ARG C 1 136 ? -50.248 125.608 -5.372 1.00 52.75 ? 188 ARG B CG 1 ATOM 4845 C CD . ARG C 1 136 ? -50.178 124.687 -4.164 1.00 64.74 ? 188 ARG B CD 1 ATOM 4846 N NE . ARG C 1 136 ? -51.424 124.684 -3.403 1.00 75.06 ? 188 ARG B NE 1 ATOM 4847 C CZ . ARG C 1 136 ? -52.505 123.983 -3.737 1.00 77.78 ? 188 ARG B CZ 1 ATOM 4848 N NH1 . ARG C 1 136 ? -53.594 124.041 -2.981 1.00 74.10 ? 188 ARG B NH1 1 ATOM 4849 N NH2 . ARG C 1 136 ? -52.504 123.225 -4.827 1.00 74.82 ? 188 ARG B NH2 1 ATOM 4850 N N . ALA C 1 137 ? -46.251 125.409 -7.241 1.00 23.78 ? 189 ALA B N 1 ATOM 4851 C CA . ALA C 1 137 ? -45.152 124.759 -7.934 1.00 23.22 ? 189 ALA B CA 1 ATOM 4852 C C . ALA C 1 137 ? -44.451 123.805 -6.979 1.00 24.13 ? 189 ALA B C 1 ATOM 4853 O O . ALA C 1 137 ? -44.461 124.011 -5.764 1.00 26.21 ? 189 ALA B O 1 ATOM 4854 C CB . ALA C 1 137 ? -44.174 125.787 -8.484 1.00 23.10 ? 189 ALA B CB 1 ATOM 4855 N N . ASP C 1 138 ? -43.851 122.759 -7.534 1.00 27.46 ? 190 ASP B N 1 ATOM 4856 C CA . ASP C 1 138 ? -43.115 121.785 -6.736 1.00 30.98 ? 190 ASP B CA 1 ATOM 4857 C C . ASP C 1 138 ? -41.670 122.215 -6.554 1.00 27.49 ? 190 ASP B C 1 ATOM 4858 O O . ASP C 1 138 ? -41.109 122.880 -7.431 1.00 24.11 ? 190 ASP B O 1 ATOM 4859 C CB . ASP C 1 138 ? -43.158 120.411 -7.395 1.00 32.26 ? 190 ASP B CB 1 ATOM 4860 C CG . ASP C 1 138 ? -44.561 119.851 -7.477 1.00 36.82 ? 190 ASP B CG 1 ATOM 4861 O OD1 . ASP C 1 138 ? -45.351 120.098 -6.542 1.00 41.56 ? 190 ASP B OD1 1 ATOM 4862 O OD2 . ASP C 1 138 ? -44.873 119.169 -8.476 1.00 41.32 ? 190 ASP B OD2 1 ATOM 4863 N N . PRO C 1 139 ? -41.059 121.833 -5.418 1.00 22.87 ? 191 PRO B N 1 ATOM 4864 C CA . PRO C 1 139 ? -39.626 122.080 -5.230 1.00 18.07 ? 191 PRO B CA 1 ATOM 4865 C C . PRO C 1 139 ? -38.847 121.581 -6.436 1.00 18.73 ? 191 PRO B C 1 ATOM 4866 O O . PRO C 1 139 ? -39.113 120.484 -6.931 1.00 21.54 ? 191 PRO B O 1 ATOM 4867 C CB . PRO C 1 139 ? -39.294 121.281 -3.968 1.00 21.98 ? 191 PRO B CB 1 ATOM 4868 C CG . PRO C 1 139 ? -40.583 121.231 -3.216 1.00 24.86 ? 191 PRO B CG 1 ATOM 4869 C CD . PRO C 1 139 ? -41.643 121.113 -4.272 1.00 24.69 ? 191 PRO B CD 1 ATOM 4870 N N . GLY C 1 140 ? -37.929 122.409 -6.918 1.00 17.55 ? 192 GLY B N 1 ATOM 4871 C CA . GLY C 1 140 ? -37.190 122.128 -8.134 1.00 19.12 ? 192 GLY B CA 1 ATOM 4872 C C . GLY C 1 140 ? -37.560 123.085 -9.251 1.00 19.30 ? 192 GLY B C 1 ATOM 4873 O O . GLY C 1 140 ? -36.746 123.387 -10.116 1.00 17.57 ? 192 GLY B O 1 ATOM 4874 N N . ALA C 1 141 ? -38.788 123.590 -9.223 1.00 18.66 ? 193 ALA B N 1 ATOM 4875 C CA . ALA C 1 141 ? -39.293 124.386 -10.335 1.00 19.49 ? 193 ALA B CA 1 ATOM 4876 C C . ALA C 1 141 ? -38.493 125.660 -10.587 1.00 14.83 ? 193 ALA B C 1 ATOM 4877 O O . ALA C 1 141 ? -38.411 126.133 -11.724 1.00 19.16 ? 193 ALA B O 1 ATOM 4878 C CB . ALA C 1 141 ? -40.760 124.736 -10.091 1.00 20.11 ? 193 ALA B CB 1 ATOM 4879 N N . ALA C 1 142 ? -37.898 126.216 -9.535 1.00 15.73 ? 194 ALA B N 1 ATOM 4880 C CA . ALA C 1 142 ? -37.193 127.489 -9.634 1.00 15.49 ? 194 ALA B CA 1 ATOM 4881 C C . ALA C 1 142 ? -35.694 127.329 -9.886 1.00 12.38 ? 194 ALA B C 1 ATOM 4882 O O . ALA C 1 142 ? -34.990 128.314 -10.078 1.00 13.05 ? 194 ALA B O 1 ATOM 4883 C CB . ALA C 1 142 ? -37.418 128.302 -8.370 1.00 16.79 ? 194 ALA B CB 1 ATOM 4884 N N . GLU C 1 143 ? -35.213 126.092 -9.879 1.00 14.11 ? 195 GLU B N 1 ATOM 4885 C CA . GLU C 1 143 ? -33.774 125.841 -9.871 1.00 15.15 ? 195 GLU B CA 1 ATOM 4886 C C . GLU C 1 143 ? -33.173 125.813 -11.267 1.00 15.23 ? 195 GLU B C 1 ATOM 4887 O O . GLU C 1 143 ? -33.886 125.632 -12.256 1.00 15.64 ? 195 GLU B O 1 ATOM 4888 C CB . GLU C 1 143 ? -33.495 124.521 -9.155 1.00 14.94 ? 195 GLU B CB 1 ATOM 4889 C CG . GLU C 1 143 ? -33.978 124.543 -7.713 1.00 16.35 ? 195 GLU B CG 1 ATOM 4890 C CD . GLU C 1 143 ? -33.824 123.214 -6.991 1.00 14.32 ? 195 GLU B CD 1 ATOM 4891 O OE1 . GLU C 1 143 ? -33.650 122.170 -7.659 1.00 16.06 ? 195 GLU B OE1 1 ATOM 4892 O OE2 . GLU C 1 143 ? -33.879 123.224 -5.743 1.00 15.88 ? 195 GLU B OE2 1 ATOM 4893 N N . VAL C 1 144 ? -31.860 126.006 -11.354 1.00 14.92 ? 196 VAL B N 1 ATOM 4894 C CA . VAL C 1 144 ? -31.193 125.845 -12.639 1.00 13.53 ? 196 VAL B CA 1 ATOM 4895 C C . VAL C 1 144 ? -31.518 124.457 -13.192 1.00 13.95 ? 196 VAL B C 1 ATOM 4896 O O . VAL C 1 144 ? -31.629 123.485 -12.438 1.00 16.20 ? 196 VAL B O 1 ATOM 4897 C CB . VAL C 1 144 ? -29.670 126.037 -12.535 1.00 14.28 ? 196 VAL B CB 1 ATOM 4898 C CG1 . VAL C 1 144 ? -29.343 127.401 -11.941 1.00 14.45 ? 196 VAL B CG1 1 ATOM 4899 C CG2 . VAL C 1 144 ? -29.023 124.922 -11.747 1.00 18.29 ? 196 VAL B CG2 1 ATOM 4900 N N . ALA C 1 145 ? -31.690 124.370 -14.507 1.00 14.79 ? 197 ALA B N 1 ATOM 4901 C CA . ALA C 1 145 ? -32.042 123.111 -15.159 1.00 14.83 ? 197 ALA B CA 1 ATOM 4902 C C . ALA C 1 145 ? -31.025 122.035 -14.829 1.00 13.92 ? 197 ALA B C 1 ATOM 4903 O O . ALA C 1 145 ? -29.837 122.314 -14.706 1.00 13.24 ? 197 ALA B O 1 ATOM 4904 C CB . ALA C 1 145 ? -32.140 123.291 -16.665 1.00 17.42 ? 197 ALA B CB 1 ATOM 4905 N N . LYS C 1 146 ? -31.503 120.810 -14.666 1.00 15.14 ? 198 LYS B N 1 ATOM 4906 C CA . LYS C 1 146 ? -30.624 119.708 -14.305 1.00 14.82 ? 198 LYS B CA 1 ATOM 4907 C C . LYS C 1 146 ? -29.444 119.586 -15.270 1.00 14.59 ? 198 LYS B C 1 ATOM 4908 O O . LYS C 1 146 ? -28.342 119.248 -14.856 1.00 13.38 ? 198 LYS B O 1 ATOM 4909 C CB . LYS C 1 146 ? -31.407 118.393 -14.267 1.00 13.75 ? 198 LYS B CB 1 ATOM 4910 C CG . LYS C 1 146 ? -30.588 117.172 -13.845 1.00 13.95 ? 198 LYS B CG 1 ATOM 4911 C CD . LYS C 1 146 ? -30.065 117.282 -12.424 1.00 14.92 ? 198 LYS B CD 1 ATOM 4912 C CE . LYS C 1 146 ? -29.313 116.027 -12.018 1.00 16.15 ? 198 LYS B CE 1 ATOM 4913 N NZ . LYS C 1 146 ? -28.892 116.084 -10.590 1.00 16.27 ? 198 LYS B NZ 1 ATOM 4914 N N . SER C 1 147 ? -29.667 119.882 -16.547 1.00 13.18 ? 199 SER B N 1 ATOM 4915 C CA . SER C 1 147 ? -28.623 119.714 -17.557 1.00 11.78 ? 199 SER B CA 1 ATOM 4916 C C . SER C 1 147 ? -27.452 120.678 -17.396 1.00 12.27 ? 199 SER B C 1 ATOM 4917 O O . SER C 1 147 ? -26.394 120.450 -17.982 1.00 13.88 ? 199 SER B O 1 ATOM 4918 C CB . SER C 1 147 ? -29.214 119.872 -18.958 1.00 13.37 ? 199 SER B CB 1 ATOM 4919 O OG . SER C 1 147 ? -29.765 121.166 -19.125 1.00 17.21 ? 199 SER B OG 1 ATOM 4920 N N . ILE C 1 148 ? -27.629 121.736 -16.599 1.00 11.83 ? 200 ILE B N 1 ATOM 4921 C CA . ILE C 1 148 ? -26.543 122.673 -16.311 1.00 12.43 ? 200 ILE B CA 1 ATOM 4922 C C . ILE C 1 148 ? -26.250 122.767 -14.808 1.00 11.54 ? 200 ILE B C 1 ATOM 4923 O O . ILE C 1 148 ? -25.570 123.692 -14.361 1.00 14.04 ? 200 ILE B O 1 ATOM 4924 C CB . ILE C 1 148 ? -26.842 124.095 -16.872 1.00 15.59 ? 200 ILE B CB 1 ATOM 4925 C CG1 . ILE C 1 148 ? -28.100 124.698 -16.230 1.00 14.50 ? 200 ILE B CG1 1 ATOM 4926 C CG2 . ILE C 1 148 ? -26.979 124.039 -18.403 1.00 17.14 ? 200 ILE B CG2 1 ATOM 4927 C CD1 . ILE C 1 148 ? -28.226 126.200 -16.430 1.00 19.81 ? 200 ILE B CD1 1 ATOM 4928 N N . GLU C 1 149 ? -26.736 121.795 -14.040 1.00 12.78 ? 201 GLU B N 1 ATOM 4929 C CA . GLU C 1 149 ? -26.477 121.750 -12.601 1.00 14.23 ? 201 GLU B CA 1 ATOM 4930 C C . GLU C 1 149 ? -24.987 121.814 -12.282 1.00 12.32 ? 201 GLU B C 1 ATOM 4931 O O . GLU C 1 149 ? -24.174 121.192 -12.960 1.00 12.97 ? 201 GLU B O 1 ATOM 4932 C CB . GLU C 1 149 ? -27.058 120.473 -11.986 1.00 12.57 ? 201 GLU B CB 1 ATOM 4933 C CG . GLU C 1 149 ? -26.907 120.441 -10.467 1.00 13.93 ? 201 GLU B CG 1 ATOM 4934 C CD . GLU C 1 149 ? -27.250 119.099 -9.828 1.00 15.44 ? 201 GLU B CD 1 ATOM 4935 O OE1 . GLU C 1 149 ? -26.983 118.030 -10.431 1.00 16.21 ? 201 GLU B OE1 1 ATOM 4936 O OE2 . GLU C 1 149 ? -27.785 119.117 -8.696 1.00 14.56 ? 201 GLU B OE2 1 ATOM 4937 N N . GLY C 1 150 ? -24.642 122.575 -11.247 1.00 10.51 ? 202 GLY B N 1 ATOM 4938 C CA . GLY C 1 150 ? -23.306 122.560 -10.686 1.00 10.97 ? 202 GLY B CA 1 ATOM 4939 C C . GLY C 1 150 ? -23.305 122.025 -9.265 1.00 10.06 ? 202 GLY B C 1 ATOM 4940 O O . GLY C 1 150 ? -24.116 121.174 -8.904 1.00 12.33 ? 202 GLY B O 1 ATOM 4941 N N . PHE C 1 151 ? -22.386 122.542 -8.460 1.00 10.21 ? 203 PHE B N 1 ATOM 4942 C CA . PHE C 1 151 ? -22.213 122.079 -7.085 1.00 11.23 ? 203 PHE B CA 1 ATOM 4943 C C . PHE C 1 151 ? -22.437 123.178 -6.051 1.00 12.83 ? 203 PHE B C 1 ATOM 4944 O O . PHE C 1 151 ? -22.333 122.924 -4.854 1.00 13.99 ? 203 PHE B O 1 ATOM 4945 C CB . PHE C 1 151 ? -20.802 121.499 -6.907 1.00 10.89 ? 203 PHE B CB 1 ATOM 4946 C CG . PHE C 1 151 ? -20.767 120.010 -6.689 1.00 12.47 ? 203 PHE B CG 1 ATOM 4947 C CD1 . PHE C 1 151 ? -21.350 119.138 -7.597 1.00 12.69 ? 203 PHE B CD1 1 ATOM 4948 C CD2 . PHE C 1 151 ? -20.125 119.483 -5.579 1.00 13.85 ? 203 PHE B CD2 1 ATOM 4949 C CE1 . PHE C 1 151 ? -21.301 117.774 -7.396 1.00 13.97 ? 203 PHE B CE1 1 ATOM 4950 C CE2 . PHE C 1 151 ? -20.076 118.118 -5.375 1.00 12.36 ? 203 PHE B CE2 1 ATOM 4951 C CZ . PHE C 1 151 ? -20.659 117.268 -6.285 1.00 12.76 ? 203 PHE B CZ 1 ATOM 4952 N N . ALA C 1 152 ? -22.724 124.401 -6.494 1.00 12.66 ? 204 ALA B N 1 ATOM 4953 C CA . ALA C 1 152 ? -22.824 125.519 -5.562 1.00 12.30 ? 204 ALA B CA 1 ATOM 4954 C C . ALA C 1 152 ? -24.163 125.540 -4.828 1.00 11.97 ? 204 ALA B C 1 ATOM 4955 O O . ALA C 1 152 ? -25.222 125.306 -5.404 1.00 12.29 ? 204 ALA B O 1 ATOM 4956 C CB . ALA C 1 152 ? -22.608 126.841 -6.295 1.00 12.56 ? 204 ALA B CB 1 ATOM 4957 N N . MET C 1 153 ? -24.100 125.814 -3.531 1.00 11.26 ? 205 MET B N 1 ATOM 4958 C CA . MET C 1 153 ? -25.295 125.935 -2.721 1.00 11.49 ? 205 MET B CA 1 ATOM 4959 C C . MET C 1 153 ? -26.143 127.125 -3.184 1.00 14.06 ? 205 MET B C 1 ATOM 4960 O O . MET C 1 153 ? -25.613 128.087 -3.737 1.00 13.55 ? 205 MET B O 1 ATOM 4961 C CB . MET C 1 153 ? -24.899 126.080 -1.247 1.00 11.17 ? 205 MET B CB 1 ATOM 4962 C CG . MET C 1 153 ? -26.080 126.025 -0.288 1.00 16.00 ? 205 MET B CG 1 ATOM 4963 S SD . MET C 1 153 ? -27.137 124.609 -0.550 1.00 14.41 ? 205 MET B SD 1 ATOM 4964 C CE . MET C 1 153 ? -28.326 124.865 0.769 1.00 14.09 ? 205 MET B CE 1 ATOM 4965 N N . TYR C 1 154 ? -27.457 127.030 -2.978 1.00 12.94 ? 206 TYR B N 1 ATOM 4966 C CA . TYR C 1 154 ? -28.388 128.131 -3.285 1.00 13.88 ? 206 TYR B CA 1 ATOM 4967 C C . TYR C 1 154 ? -27.883 129.449 -2.711 1.00 15.22 ? 206 TYR B C 1 ATOM 4968 O O . TYR C 1 154 ? -27.268 129.478 -1.643 1.00 14.47 ? 206 TYR B O 1 ATOM 4969 C CB . TYR C 1 154 ? -29.778 127.817 -2.738 1.00 16.21 ? 206 TYR B CB 1 ATOM 4970 C CG . TYR C 1 154 ? -30.298 126.485 -3.205 1.00 14.15 ? 206 TYR B CG 1 ATOM 4971 C CD1 . TYR C 1 154 ? -30.622 126.273 -4.541 1.00 14.78 ? 206 TYR B CD1 1 ATOM 4972 C CD2 . TYR C 1 154 ? -30.435 125.420 -2.322 1.00 14.59 ? 206 TYR B CD2 1 ATOM 4973 C CE1 . TYR C 1 154 ? -31.072 125.043 -4.977 1.00 12.57 ? 206 TYR B CE1 1 ATOM 4974 C CE2 . TYR C 1 154 ? -30.887 124.190 -2.748 1.00 16.39 ? 206 TYR B CE2 1 ATOM 4975 C CZ . TYR C 1 154 ? -31.206 123.999 -4.074 1.00 13.05 ? 206 TYR B CZ 1 ATOM 4976 O OH . TYR C 1 154 ? -31.658 122.773 -4.501 1.00 14.33 ? 206 TYR B OH 1 ATOM 4977 N N . ALA C 1 155 ? -28.145 130.547 -3.413 1.00 15.82 ? 207 ALA B N 1 ATOM 4978 C CA . ALA C 1 155 ? -27.586 131.836 -3.024 1.00 14.21 ? 207 ALA B CA 1 ATOM 4979 C C . ALA C 1 155 ? -28.126 132.326 -1.679 1.00 13.89 ? 207 ALA B C 1 ATOM 4980 O O . ALA C 1 155 ? -27.406 132.994 -0.936 1.00 16.01 ? 207 ALA B O 1 ATOM 4981 C CB . ALA C 1 155 ? -27.861 132.881 -4.106 1.00 16.23 ? 207 ALA B CB 1 ATOM 4982 N N . GLY C 1 156 ? -29.383 132.001 -1.389 1.00 16.52 ? 208 GLY B N 1 ATOM 4983 C CA . GLY C 1 156 ? -30.023 132.447 -0.160 1.00 17.05 ? 208 GLY B CA 1 ATOM 4984 C C . GLY C 1 156 ? -31.401 131.834 -0.008 1.00 17.69 ? 208 GLY B C 1 ATOM 4985 O O . GLY C 1 156 ? -31.871 131.111 -0.884 1.00 16.95 ? 208 GLY B O 1 ATOM 4986 N N . TYR C 1 157 ? -32.052 132.119 1.118 1.00 19.23 ? 209 TYR B N 1 ATOM 4987 C CA . TYR C 1 157 ? -33.377 131.593 1.399 1.00 18.18 ? 209 TYR B CA 1 ATOM 4988 C C . TYR C 1 157 ? -34.074 132.510 2.400 1.00 20.26 ? 209 TYR B C 1 ATOM 4989 O O . TYR C 1 157 ? -33.493 132.869 3.421 1.00 20.17 ? 209 TYR B O 1 ATOM 4990 C CB . TYR C 1 157 ? -33.306 130.160 1.940 1.00 18.87 ? 209 TYR B CB 1 ATOM 4991 C CG . TYR C 1 157 ? -34.658 129.604 2.299 1.00 18.24 ? 209 TYR B CG 1 ATOM 4992 C CD1 . TYR C 1 157 ? -35.621 129.384 1.326 1.00 19.63 ? 209 TYR B CD1 1 ATOM 4993 C CD2 . TYR C 1 157 ? -34.978 129.307 3.616 1.00 19.52 ? 209 TYR B CD2 1 ATOM 4994 C CE1 . TYR C 1 157 ? -36.867 128.880 1.654 1.00 24.02 ? 209 TYR B CE1 1 ATOM 4995 C CE2 . TYR C 1 157 ? -36.221 128.801 3.951 1.00 19.76 ? 209 TYR B CE2 1 ATOM 4996 C CZ . TYR C 1 157 ? -37.161 128.591 2.970 1.00 21.21 ? 209 TYR B CZ 1 ATOM 4997 O OH . TYR C 1 157 ? -38.406 128.086 3.300 1.00 27.17 ? 209 TYR B OH 1 ATOM 4998 N N . LEU C 1 158 ? -35.312 132.884 2.077 1.00 20.37 ? 210 LEU B N 1 ATOM 4999 C CA . LEU C 1 158 ? -36.057 133.915 2.808 1.00 22.24 ? 210 LEU B CA 1 ATOM 5000 C C . LEU C 1 158 ? -35.309 135.249 2.716 1.00 21.57 ? 210 LEU B C 1 ATOM 5001 O O . LEU C 1 158 ? -34.251 135.340 2.096 1.00 20.32 ? 210 LEU B O 1 ATOM 5002 C CB . LEU C 1 158 ? -36.289 133.490 4.269 1.00 21.30 ? 210 LEU B CB 1 ATOM 5003 C CG . LEU C 1 158 ? -37.035 132.159 4.406 1.00 23.63 ? 210 LEU B CG 1 ATOM 5004 C CD1 . LEU C 1 158 ? -37.161 131.720 5.860 1.00 24.29 ? 210 LEU B CD1 1 ATOM 5005 C CD2 . LEU C 1 158 ? -38.402 132.202 3.758 1.00 31.58 ? 210 LEU B CD2 1 ATOM 5006 N N . THR C 1 159 ? -35.854 136.312 3.299 1.00 24.12 ? 211 THR B N 1 ATOM 5007 C CA . THR C 1 159 ? -35.216 137.615 3.136 1.00 21.18 ? 211 THR B CA 1 ATOM 5008 C C . THR C 1 159 ? -33.883 137.696 3.861 1.00 19.63 ? 211 THR B C 1 ATOM 5009 O O . THR C 1 159 ? -32.983 138.418 3.449 1.00 17.93 ? 211 THR B O 1 ATOM 5010 C CB . THR C 1 159 ? -36.112 138.771 3.634 1.00 26.10 ? 211 THR B CB 1 ATOM 5011 O OG1 . THR C 1 159 ? -36.565 138.500 4.966 1.00 23.74 ? 211 THR B OG1 1 ATOM 5012 C CG2 . THR C 1 159 ? -37.303 138.952 2.718 1.00 21.98 ? 211 THR B CG2 1 ATOM 5013 N N . HIS C 1 160 ? -33.754 136.946 4.946 1.00 21.77 ? 212 HIS B N 1 ATOM 5014 C CA . HIS C 1 160 ? -32.551 137.004 5.758 1.00 23.03 ? 212 HIS B CA 1 ATOM 5015 C C . HIS C 1 160 ? -32.562 135.833 6.721 1.00 15.40 ? 212 HIS B C 1 ATOM 5016 O O . HIS C 1 160 ? -33.576 135.152 6.875 1.00 21.66 ? 212 HIS B O 1 ATOM 5017 C CB . HIS C 1 160 ? -32.460 138.330 6.523 1.00 25.61 ? 212 HIS B CB 1 ATOM 5018 C CG . HIS C 1 160 ? -33.578 138.535 7.496 1.00 30.69 ? 212 HIS B CG 1 ATOM 5019 N ND1 . HIS C 1 160 ? -34.867 138.816 7.097 1.00 26.72 ? 212 HIS B ND1 1 ATOM 5020 C CD2 . HIS C 1 160 ? -33.603 138.490 8.850 1.00 31.55 ? 212 HIS B CD2 1 ATOM 5021 C CE1 . HIS C 1 160 ? -35.640 138.934 8.163 1.00 35.69 ? 212 HIS B CE1 1 ATOM 5022 N NE2 . HIS C 1 160 ? -34.897 138.740 9.239 1.00 32.45 ? 212 HIS B NE2 1 ATOM 5023 N N . CYS C 1 161 ? -31.412 135.607 7.348 1.00 19.72 ? 213 CYS B N 1 ATOM 5024 C CA . CYS C 1 161 ? -31.224 134.512 8.288 1.00 23.11 ? 213 CYS B CA 1 ATOM 5025 C C . CYS C 1 161 ? -30.563 135.013 9.577 1.00 20.35 ? 213 CYS B C 1 ATOM 5026 O O . CYS C 1 161 ? -29.536 135.689 9.516 1.00 19.99 ? 213 CYS B O 1 ATOM 5027 C CB . CYS C 1 161 ? -30.367 133.424 7.645 1.00 21.79 ? 213 CYS B CB 1 ATOM 5028 S SG . CYS C 1 161 ? -29.963 132.077 8.762 1.00 22.81 ? 213 CYS B SG 1 ATOM 5029 N N . PRO C 1 162 ? -31.153 134.696 10.750 1.00 19.73 ? 214 PRO B N 1 ATOM 5030 C CA . PRO C 1 162 ? -32.390 133.934 10.958 1.00 23.61 ? 214 PRO B CA 1 ATOM 5031 C C . PRO C 1 162 ? -33.615 134.764 10.603 1.00 21.31 ? 214 PRO B C 1 ATOM 5032 O O . PRO C 1 162 ? -33.667 135.929 10.986 1.00 26.90 ? 214 PRO B O 1 ATOM 5033 C CB . PRO C 1 162 ? -32.355 133.607 12.457 1.00 30.17 ? 214 PRO B CB 1 ATOM 5034 C CG . PRO C 1 162 ? -31.566 134.705 13.053 1.00 24.62 ? 214 PRO B CG 1 ATOM 5035 C CD . PRO C 1 162 ? -30.549 135.114 12.029 1.00 27.54 ? 214 PRO B CD 1 ATOM 5036 N N . TYR C 1 163 ? -34.576 134.183 9.896 1.00 24.18 ? 215 TYR B N 1 ATOM 5037 C CA . TYR C 1 163 ? -35.699 134.966 9.403 1.00 22.28 ? 215 TYR B CA 1 ATOM 5038 C C . TYR C 1 163 ? -36.625 135.382 10.544 1.00 31.62 ? 215 TYR B C 1 ATOM 5039 O O . TYR C 1 163 ? -37.170 136.486 10.531 1.00 28.75 ? 215 TYR B O 1 ATOM 5040 C CB . TYR C 1 163 ? -36.496 134.199 8.354 1.00 22.92 ? 215 TYR B CB 1 ATOM 5041 C CG . TYR C 1 163 ? -37.728 134.960 7.933 1.00 25.76 ? 215 TYR B CG 1 ATOM 5042 C CD1 . TYR C 1 163 ? -37.623 136.099 7.147 1.00 31.26 ? 215 TYR B CD1 1 ATOM 5043 C CD2 . TYR C 1 163 ? -38.990 134.558 8.347 1.00 30.25 ? 215 TYR B CD2 1 ATOM 5044 C CE1 . TYR C 1 163 ? -38.749 136.812 6.774 1.00 25.38 ? 215 TYR B CE1 1 ATOM 5045 C CE2 . TYR C 1 163 ? -40.120 135.261 7.978 1.00 25.85 ? 215 TYR B CE2 1 ATOM 5046 C CZ . TYR C 1 163 ? -39.993 136.384 7.192 1.00 29.87 ? 215 TYR B CZ 1 ATOM 5047 O OH . TYR C 1 163 ? -41.124 137.083 6.830 1.00 31.29 ? 215 TYR B OH 1 ATOM 5048 N N . ASN C 1 164 ? -36.811 134.491 11.516 1.00 26.38 ? 216 ASN B N 1 ATOM 5049 C CA . ASN C 1 164 ? -37.590 134.815 12.712 1.00 25.64 ? 216 ASN B CA 1 ATOM 5050 C C . ASN C 1 164 ? -36.849 134.371 13.974 1.00 33.71 ? 216 ASN B C 1 ATOM 5051 O O . ASN C 1 164 ? -35.840 133.671 13.894 1.00 28.23 ? 216 ASN B O 1 ATOM 5052 C CB . ASN C 1 164 ? -38.992 134.188 12.636 1.00 29.44 ? 216 ASN B CB 1 ATOM 5053 C CG . ASN C 1 164 ? -38.981 132.665 12.709 1.00 25.20 ? 216 ASN B CG 1 ATOM 5054 O OD1 . ASN C 1 164 ? -38.261 132.069 13.509 1.00 29.20 ? 216 ASN B OD1 1 ATOM 5055 N ND2 . ASN C 1 164 ? -39.810 132.030 11.885 1.00 27.97 ? 216 ASN B ND2 1 ATOM 5056 N N . VAL C 1 165 ? -37.347 134.786 15.134 1.00 31.59 ? 217 VAL B N 1 ATOM 5057 C CA . VAL C 1 165 ? -36.653 134.532 16.394 1.00 28.84 ? 217 VAL B CA 1 ATOM 5058 C C . VAL C 1 165 ? -36.607 133.041 16.722 1.00 24.23 ? 217 VAL B C 1 ATOM 5059 O O . VAL C 1 165 ? -35.711 132.588 17.434 1.00 30.23 ? 217 VAL B O 1 ATOM 5060 C CB . VAL C 1 165 ? -37.315 135.292 17.573 1.00 33.05 ? 217 VAL B CB 1 ATOM 5061 C CG1 . VAL C 1 165 ? -37.174 136.795 17.379 1.00 38.47 ? 217 VAL B CG1 1 ATOM 5062 C CG2 . VAL C 1 165 ? -38.780 134.899 17.724 1.00 33.14 ? 217 VAL B CG2 1 ATOM 5063 N N . ASN C 1 166 ? -37.559 132.280 16.196 1.00 24.02 ? 218 ASN B N 1 ATOM 5064 C CA . ASN C 1 166 ? -37.616 130.854 16.470 1.00 22.86 ? 218 ASN B CA 1 ATOM 5065 C C . ASN C 1 166 ? -36.474 130.111 15.780 1.00 32.27 ? 218 ASN B C 1 ATOM 5066 O O . ASN C 1 166 ? -35.945 129.146 16.326 1.00 27.74 ? 218 ASN B O 1 ATOM 5067 C CB . ASN C 1 166 ? -38.964 130.283 16.042 1.00 30.07 ? 218 ASN B CB 1 ATOM 5068 C CG . ASN C 1 166 ? -40.116 130.879 16.824 1.00 34.56 ? 218 ASN B CG 1 ATOM 5069 O OD1 . ASN C 1 166 ? -39.910 131.696 17.722 1.00 34.73 ? 218 ASN B OD1 1 ATOM 5070 N ND2 . ASN C 1 166 ? -41.333 130.479 16.484 1.00 35.13 ? 218 ASN B ND2 1 ATOM 5071 N N . VAL C 1 167 ? -36.094 130.563 14.588 1.00 32.35 ? 219 VAL B N 1 ATOM 5072 C CA . VAL C 1 167 ? -34.925 130.007 13.909 1.00 28.02 ? 219 VAL B CA 1 ATOM 5073 C C . VAL C 1 167 ? -33.704 130.149 14.814 1.00 26.78 ? 219 VAL B C 1 ATOM 5074 O O . VAL C 1 167 ? -32.980 129.180 15.061 1.00 26.52 ? 219 VAL B O 1 ATOM 5075 C CB . VAL C 1 167 ? -34.658 130.704 12.548 1.00 24.49 ? 219 VAL B CB 1 ATOM 5076 C CG1 . VAL C 1 167 ? -33.355 130.208 11.922 1.00 26.10 ? 219 VAL B CG1 1 ATOM 5077 C CG2 . VAL C 1 167 ? -35.812 130.458 11.601 1.00 25.72 ? 219 VAL B CG2 1 ATOM 5078 N N . TYR C 1 168 ? -33.493 131.351 15.335 1.00 25.27 ? 220 TYR B N 1 ATOM 5079 C CA . TYR C 1 168 ? -32.343 131.607 16.182 1.00 29.36 ? 220 TYR B CA 1 ATOM 5080 C C . TYR C 1 168 ? -32.432 130.871 17.526 1.00 30.66 ? 220 TYR B C 1 ATOM 5081 O O . TYR C 1 168 ? -31.484 130.206 17.929 1.00 30.99 ? 220 TYR B O 1 ATOM 5082 C CB . TYR C 1 168 ? -32.185 133.107 16.423 1.00 27.79 ? 220 TYR B CB 1 ATOM 5083 C CG . TYR C 1 168 ? -30.892 133.475 17.113 1.00 34.02 ? 220 TYR B CG 1 ATOM 5084 C CD1 . TYR C 1 168 ? -29.670 133.315 16.472 1.00 29.43 ? 220 TYR B CD1 1 ATOM 5085 C CD2 . TYR C 1 168 ? -30.891 133.987 18.404 1.00 34.09 ? 220 TYR B CD2 1 ATOM 5086 C CE1 . TYR C 1 168 ? -28.489 133.651 17.094 1.00 30.92 ? 220 TYR B CE1 1 ATOM 5087 C CE2 . TYR C 1 168 ? -29.712 134.326 19.036 1.00 32.34 ? 220 TYR B CE2 1 ATOM 5088 C CZ . TYR C 1 168 ? -28.511 134.154 18.377 1.00 37.33 ? 220 TYR B CZ 1 ATOM 5089 O OH . TYR C 1 168 ? -27.327 134.486 18.993 1.00 42.92 ? 220 TYR B OH 1 ATOM 5090 N N . ARG C 1 169 ? -33.566 130.973 18.211 1.00 31.46 ? 221 ARG B N 1 ATOM 5091 C CA . ARG C 1 169 ? -33.652 130.486 19.590 1.00 30.42 ? 221 ARG B CA 1 ATOM 5092 C C . ARG C 1 169 ? -33.830 128.976 19.720 1.00 32.81 ? 221 ARG B C 1 ATOM 5093 O O . ARG C 1 169 ? -33.398 128.386 20.711 1.00 35.15 ? 221 ARG B O 1 ATOM 5094 C CB . ARG C 1 169 ? -34.801 131.183 20.319 1.00 29.02 ? 221 ARG B CB 1 ATOM 5095 C CG . ARG C 1 169 ? -34.568 132.663 20.526 1.00 35.50 ? 221 ARG B CG 1 ATOM 5096 C CD . ARG C 1 169 ? -35.784 133.338 21.138 1.00 37.20 ? 221 ARG B CD 1 ATOM 5097 N NE . ARG C 1 169 ? -35.695 134.793 21.043 1.00 44.63 ? 221 ARG B NE 1 ATOM 5098 C CZ . ARG C 1 169 ? -36.667 135.630 21.395 1.00 47.14 ? 221 ARG B CZ 1 ATOM 5099 N NH1 . ARG C 1 169 ? -36.491 136.937 21.268 1.00 40.13 ? 221 ARG B NH1 1 ATOM 5100 N NH2 . ARG C 1 169 ? -37.817 135.164 21.867 1.00 39.15 ? 221 ARG B NH2 1 ATOM 5101 N N . GLN C 1 170 ? -34.463 128.353 18.734 1.00 24.56 ? 222 GLN B N 1 ATOM 5102 C CA . GLN C 1 170 ? -34.823 126.946 18.834 1.00 25.47 ? 222 GLN B CA 1 ATOM 5103 C C . GLN C 1 170 ? -33.919 126.023 18.018 1.00 27.44 ? 222 GLN B C 1 ATOM 5104 O O . GLN C 1 170 ? -33.808 124.837 18.332 1.00 29.04 ? 222 GLN B O 1 ATOM 5105 C CB . GLN C 1 170 ? -36.265 126.758 18.393 1.00 30.41 ? 222 GLN B CB 1 ATOM 5106 C CG . GLN C 1 170 ? -37.219 127.718 19.075 1.00 35.79 ? 222 GLN B CG 1 ATOM 5107 C CD . GLN C 1 170 ? -38.374 127.006 19.723 1.00 45.34 ? 222 GLN B CD 1 ATOM 5108 O OE1 . GLN C 1 170 ? -38.317 126.651 20.900 1.00 60.38 ? 222 GLN B OE1 1 ATOM 5109 N NE2 . GLN C 1 170 ? -39.434 126.782 18.957 1.00 52.40 ? 222 GLN B NE2 1 ATOM 5110 N N . ASP C 1 171 ? -33.296 126.558 16.969 1.00 30.24 ? 223 ASP B N 1 ATOM 5111 C CA . ASP C 1 171 ? -32.396 125.761 16.133 1.00 26.49 ? 223 ASP B CA 1 ATOM 5112 C C . ASP C 1 171 ? -30.932 126.174 16.320 1.00 24.14 ? 223 ASP B C 1 ATOM 5113 O O . ASP C 1 171 ? -30.075 125.316 16.519 1.00 26.08 ? 223 ASP B O 1 ATOM 5114 C CB . ASP C 1 171 ? -32.785 125.867 14.645 1.00 21.49 ? 223 ASP B CB 1 ATOM 5115 C CG . ASP C 1 171 ? -33.887 124.893 14.241 1.00 25.62 ? 223 ASP B CG 1 ATOM 5116 O OD1 . ASP C 1 171 ? -34.256 123.996 15.032 1.00 25.43 ? 223 ASP B OD1 1 ATOM 5117 O OD2 . ASP C 1 171 ? -34.386 125.012 13.102 1.00 26.16 ? 223 ASP B OD2 1 ATOM 5118 N N . MET C 1 172 ? -30.640 127.472 16.280 1.00 22.02 ? 224 MET B N 1 ATOM 5119 C CA . MET C 1 172 ? -29.256 127.946 16.307 1.00 20.80 ? 224 MET B CA 1 ATOM 5120 C C . MET C 1 172 ? -28.579 127.936 17.687 1.00 26.73 ? 224 MET B C 1 ATOM 5121 O O . MET C 1 172 ? -27.602 127.222 17.875 1.00 26.58 ? 224 MET B O 1 ATOM 5122 C CB . MET C 1 172 ? -29.176 129.358 15.731 1.00 25.82 ? 224 MET B CB 1 ATOM 5123 C CG . MET C 1 172 ? -29.186 129.401 14.214 1.00 27.04 ? 224 MET B CG 1 ATOM 5124 S SD . MET C 1 172 ? -29.191 131.081 13.570 1.00 28.87 ? 224 MET B SD 1 ATOM 5125 C CE . MET C 1 172 ? -28.981 130.771 11.819 1.00 31.22 ? 224 MET B CE 1 ATOM 5126 N N . VAL C 1 173 ? -29.064 128.728 18.643 1.00 28.35 ? 225 VAL B N 1 ATOM 5127 C CA . VAL C 1 173 ? -28.324 128.902 19.898 1.00 28.05 ? 225 VAL B CA 1 ATOM 5128 C C . VAL C 1 173 ? -28.212 127.607 20.704 1.00 23.05 ? 225 VAL B C 1 ATOM 5129 O O . VAL C 1 173 ? -27.273 127.448 21.480 1.00 30.36 ? 225 VAL B O 1 ATOM 5130 C CB . VAL C 1 173 ? -28.953 129.989 20.816 1.00 35.03 ? 225 VAL B CB 1 ATOM 5131 C CG1 . VAL C 1 173 ? -28.706 131.381 20.251 1.00 36.70 ? 225 VAL B CG1 1 ATOM 5132 C CG2 . VAL C 1 173 ? -30.426 129.722 21.040 1.00 37.54 ? 225 VAL B CG2 1 ATOM 5133 N N . THR C 1 174 ? -29.158 126.691 20.522 1.00 24.49 ? 226 THR B N 1 ATOM 5134 C CA . THR C 1 174 ? -29.139 125.416 21.237 1.00 23.95 ? 226 THR B CA 1 ATOM 5135 C C . THR C 1 174 ? -28.389 124.325 20.457 1.00 24.11 ? 226 THR B C 1 ATOM 5136 O O . THR C 1 174 ? -28.408 123.155 20.842 1.00 24.83 ? 226 THR B O 1 ATOM 5137 C CB . THR C 1 174 ? -30.563 124.929 21.537 1.00 33.01 ? 226 THR B CB 1 ATOM 5138 O OG1 . THR C 1 174 ? -31.338 124.935 20.332 1.00 32.25 ? 226 THR B OG1 1 ATOM 5139 C CG2 . THR C 1 174 ? -31.226 125.831 22.577 1.00 36.70 ? 226 THR B CG2 1 ATOM 5140 N N . ASP C 1 175 ? -27.740 124.719 19.363 1.00 26.18 ? 227 ASP B N 1 ATOM 5141 C CA . ASP C 1 175 ? -26.901 123.813 18.571 1.00 26.90 ? 227 ASP B CA 1 ATOM 5142 C C . ASP C 1 175 ? -25.503 123.840 19.167 1.00 20.43 ? 227 ASP B C 1 ATOM 5143 O O . ASP C 1 175 ? -24.870 124.890 19.234 1.00 22.82 ? 227 ASP B O 1 ATOM 5144 C CB . ASP C 1 175 ? -26.880 124.240 17.091 1.00 24.17 ? 227 ASP B CB 1 ATOM 5145 C CG . ASP C 1 175 ? -26.250 123.197 16.167 1.00 28.08 ? 227 ASP B CG 1 ATOM 5146 O OD1 . ASP C 1 175 ? -25.309 122.485 16.583 1.00 23.56 ? 227 ASP B OD1 1 ATOM 5147 O OD2 . ASP C 1 175 ? -26.698 123.101 15.004 1.00 23.12 ? 227 ASP B OD2 1 ATOM 5148 N N . LYS C 1 176 ? -25.021 122.680 19.605 1.00 21.42 ? 228 LYS B N 1 ATOM 5149 C CA . LYS C 1 176 ? -23.733 122.605 20.279 1.00 23.43 ? 228 LYS B CA 1 ATOM 5150 C C . LYS C 1 176 ? -22.573 123.022 19.377 1.00 21.94 ? 228 LYS B C 1 ATOM 5151 O O . LYS C 1 176 ? -21.499 123.337 19.870 1.00 22.28 ? 228 LYS B O 1 ATOM 5152 C CB . LYS C 1 176 ? -23.513 121.190 20.822 1.00 23.58 ? 228 LYS B CB 1 ATOM 5153 C CG . LYS C 1 176 ? -24.576 120.769 21.826 1.00 32.44 ? 228 LYS B CG 1 ATOM 5154 C CD . LYS C 1 176 ? -24.320 119.380 22.394 1.00 40.77 ? 228 LYS B CD 1 ATOM 5155 C CE . LYS C 1 176 ? -25.523 118.889 23.185 1.00 48.33 ? 228 LYS B CE 1 ATOM 5156 N NZ . LYS C 1 176 ? -25.908 119.833 24.272 1.00 48.77 ? 228 LYS B NZ 1 ATOM 5157 N N . GLU C 1 177 ? -22.788 123.055 18.062 1.00 22.56 ? 229 GLU B N 1 ATOM 5158 C CA . GLU C 1 177 ? -21.747 123.544 17.154 1.00 20.16 ? 229 GLU B CA 1 ATOM 5159 C C . GLU C 1 177 ? -21.856 125.040 16.857 1.00 21.14 ? 229 GLU B C 1 ATOM 5160 O O . GLU C 1 177 ? -20.943 125.628 16.278 1.00 20.54 ? 229 GLU B O 1 ATOM 5161 C CB . GLU C 1 177 ? -21.772 122.766 15.834 1.00 19.56 ? 229 GLU B CB 1 ATOM 5162 C CG . GLU C 1 177 ? -21.299 121.327 15.976 1.00 21.09 ? 229 GLU B CG 1 ATOM 5163 C CD . GLU C 1 177 ? -20.748 120.765 14.682 1.00 19.99 ? 229 GLU B CD 1 ATOM 5164 O OE1 . GLU C 1 177 ? -21.558 120.430 13.796 1.00 19.35 ? 229 GLU B OE1 1 ATOM 5165 O OE2 . GLU C 1 177 ? -19.503 120.677 14.561 1.00 18.31 ? 229 GLU B OE2 1 ATOM 5166 N N . PHE C 1 178 ? -22.965 125.653 17.260 1.00 22.06 ? 230 PHE B N 1 ATOM 5167 C CA . PHE C 1 178 ? -23.158 127.081 17.042 1.00 24.79 ? 230 PHE B CA 1 ATOM 5168 C C . PHE C 1 178 ? -22.546 127.878 18.185 1.00 27.28 ? 230 PHE B C 1 ATOM 5169 O O . PHE C 1 178 ? -22.580 127.451 19.337 1.00 30.07 ? 230 PHE B O 1 ATOM 5170 C CB . PHE C 1 178 ? -24.647 127.410 16.904 1.00 22.98 ? 230 PHE B CB 1 ATOM 5171 C CG . PHE C 1 178 ? -24.921 128.817 16.430 1.00 24.86 ? 230 PHE B CG 1 ATOM 5172 C CD1 . PHE C 1 178 ? -24.973 129.110 15.074 1.00 24.35 ? 230 PHE B CD1 1 ATOM 5173 C CD2 . PHE C 1 178 ? -25.128 129.846 17.340 1.00 30.30 ? 230 PHE B CD2 1 ATOM 5174 C CE1 . PHE C 1 178 ? -25.224 130.401 14.634 1.00 29.01 ? 230 PHE B CE1 1 ATOM 5175 C CE2 . PHE C 1 178 ? -25.383 131.142 16.905 1.00 28.68 ? 230 PHE B CE2 1 ATOM 5176 C CZ . PHE C 1 178 ? -25.433 131.419 15.553 1.00 26.64 ? 230 PHE B CZ 1 ATOM 5177 N N . ASP C 1 179 ? -21.975 129.028 17.844 1.00 24.88 ? 231 ASP B N 1 ATOM 5178 C CA . ASP C 1 179 ? -21.455 129.976 18.822 1.00 26.88 ? 231 ASP B CA 1 ATOM 5179 C C . ASP C 1 179 ? -21.786 131.393 18.358 1.00 31.05 ? 231 ASP B C 1 ATOM 5180 O O . ASP C 1 179 ? -21.392 131.804 17.267 1.00 29.76 ? 231 ASP B O 1 ATOM 5181 C CB . ASP C 1 179 ? -19.949 129.808 19.000 1.00 24.40 ? 231 ASP B CB 1 ATOM 5182 C CG . ASP C 1 179 ? -19.375 130.777 20.014 1.00 34.30 ? 231 ASP B CG 1 ATOM 5183 O OD1 . ASP C 1 179 ? -19.349 130.433 21.215 1.00 41.94 ? 231 ASP B OD1 1 ATOM 5184 O OD2 . ASP C 1 179 ? -18.953 131.880 19.612 1.00 29.19 ? 231 ASP B OD2 1 ATOM 5185 N N . SER C 1 180 ? -22.507 132.140 19.188 1.00 30.88 ? 232 SER B N 1 ATOM 5186 C CA . SER C 1 180 ? -23.067 133.418 18.764 1.00 27.77 ? 232 SER B CA 1 ATOM 5187 C C . SER C 1 180 ? -22.001 134.490 18.550 1.00 26.68 ? 232 SER B C 1 ATOM 5188 O O . SER C 1 180 ? -22.271 135.530 17.942 1.00 29.97 ? 232 SER B O 1 ATOM 5189 C CB . SER C 1 180 ? -24.097 133.904 19.790 1.00 35.06 ? 232 SER B CB 1 ATOM 5190 O OG . SER C 1 180 ? -23.499 134.107 21.058 1.00 44.55 ? 232 SER B OG 1 ATOM 5191 N N . THR C 1 181 ? -20.791 134.246 19.043 1.00 27.82 ? 233 THR B N 1 ATOM 5192 C CA . THR C 1 181 ? -19.689 135.179 18.836 1.00 24.75 ? 233 THR B CA 1 ATOM 5193 C C . THR C 1 181 ? -18.965 134.873 17.527 1.00 30.63 ? 233 THR B C 1 ATOM 5194 O O . THR C 1 181 ? -18.696 135.776 16.732 1.00 29.38 ? 233 THR B O 1 ATOM 5195 C CB . THR C 1 181 ? -18.690 135.140 20.010 1.00 37.04 ? 233 THR B CB 1 ATOM 5196 O OG1 . THR C 1 181 ? -19.362 135.545 21.209 1.00 35.86 ? 233 THR B OG1 1 ATOM 5197 C CG2 . THR C 1 181 ? -17.505 136.069 19.756 1.00 34.72 ? 233 THR B CG2 1 ATOM 5198 N N . VAL C 1 182 ? -18.644 133.603 17.301 1.00 27.54 ? 234 VAL B N 1 ATOM 5199 C CA . VAL C 1 182 ? -18.038 133.203 16.038 1.00 26.39 ? 234 VAL B CA 1 ATOM 5200 C C . VAL C 1 182 ? -19.004 133.520 14.895 1.00 22.28 ? 234 VAL B C 1 ATOM 5201 O O . VAL C 1 182 ? -18.589 133.972 13.822 1.00 25.31 ? 234 VAL B O 1 ATOM 5202 C CB . VAL C 1 182 ? -17.681 131.704 16.026 1.00 24.46 ? 234 VAL B CB 1 ATOM 5203 C CG1 . VAL C 1 182 ? -17.120 131.289 14.666 1.00 25.57 ? 234 VAL B CG1 1 ATOM 5204 C CG2 . VAL C 1 182 ? -16.676 131.386 17.126 1.00 28.38 ? 234 VAL B CG2 1 ATOM 5205 N N . CYS C 1 183 ? -20.289 133.295 15.150 1.00 22.27 ? 235 CYS B N 1 ATOM 5206 C CA . CYS C 1 183 ? -21.342 133.496 14.157 1.00 19.82 ? 235 CYS B CA 1 ATOM 5207 C C . CYS C 1 183 ? -22.102 134.808 14.382 1.00 22.42 ? 235 CYS B C 1 ATOM 5208 O O . CYS C 1 183 ? -23.320 134.848 14.223 1.00 24.11 ? 235 CYS B O 1 ATOM 5209 C CB . CYS C 1 183 ? -22.337 132.334 14.192 1.00 22.86 ? 235 CYS B CB 1 ATOM 5210 S SG . CYS C 1 183 ? -21.590 130.683 14.041 1.00 23.79 ? 235 CYS B SG 1 ATOM 5211 N N . ASN C 1 184 ? -21.396 135.870 14.748 1.00 25.41 ? 236 ASN B N 1 ATOM 5212 C CA . ASN C 1 184 ? -22.069 137.124 15.102 1.00 26.93 ? 236 ASN B CA 1 ATOM 5213 C C . ASN C 1 184 ? -22.588 137.892 13.883 1.00 33.79 ? 236 ASN B C 1 ATOM 5214 O O . ASN C 1 184 ? -23.108 139.000 14.014 1.00 30.01 ? 236 ASN B O 1 ATOM 5215 C CB . ASN C 1 184 ? -21.133 138.021 15.918 1.00 25.57 ? 236 ASN B CB 1 ATOM 5216 C CG . ASN C 1 184 ? -19.869 138.390 15.169 1.00 26.75 ? 236 ASN B CG 1 ATOM 5217 O OD1 . ASN C 1 184 ? -19.777 138.231 13.953 1.00 32.40 ? 236 ASN B OD1 1 ATOM 5218 N ND2 . ASN C 1 184 ? -18.883 138.899 15.898 1.00 37.68 ? 236 ASN B ND2 1 ATOM 5219 N N . PHE C 1 185 ? -22.435 137.297 12.703 1.00 25.76 ? 237 PHE B N 1 ATOM 5220 C CA . PHE C 1 185 ? -22.932 137.872 11.455 1.00 22.46 ? 237 PHE B CA 1 ATOM 5221 C C . PHE C 1 185 ? -24.213 137.177 11.006 1.00 22.40 ? 237 PHE B C 1 ATOM 5222 O O . PHE C 1 185 ? -24.740 137.469 9.932 1.00 26.44 ? 237 PHE B O 1 ATOM 5223 C CB . PHE C 1 185 ? -21.868 137.763 10.361 1.00 25.09 ? 237 PHE B CB 1 ATOM 5224 C CG . PHE C 1 185 ? -21.415 136.354 10.110 1.00 24.15 ? 237 PHE B CG 1 ATOM 5225 C CD1 . PHE C 1 185 ? -20.354 135.818 10.820 1.00 28.49 ? 237 PHE B CD1 1 ATOM 5226 C CD2 . PHE C 1 185 ? -22.060 135.561 9.179 1.00 22.20 ? 237 PHE B CD2 1 ATOM 5227 C CE1 . PHE C 1 185 ? -19.939 134.517 10.601 1.00 23.21 ? 237 PHE B CE1 1 ATOM 5228 C CE2 . PHE C 1 185 ? -21.648 134.255 8.954 1.00 23.13 ? 237 PHE B CE2 1 ATOM 5229 C CZ . PHE C 1 185 ? -20.587 133.737 9.670 1.00 22.87 ? 237 PHE B CZ 1 ATOM 5230 N N . VAL C 1 186 ? -24.716 136.255 11.817 1.00 22.15 ? 238 VAL B N 1 ATOM 5231 C CA . VAL C 1 186 ? -25.959 135.575 11.499 1.00 23.58 ? 238 VAL B CA 1 ATOM 5232 C C . VAL C 1 186 ? -26.762 135.343 12.784 1.00 30.31 ? 238 VAL B C 1 ATOM 5233 O O . VAL C 1 186 ? -27.078 134.215 13.155 1.00 29.53 ? 238 VAL B O 1 ATOM 5234 C CB . VAL C 1 186 ? -25.675 134.243 10.722 1.00 29.42 ? 238 VAL B CB 1 ATOM 5235 C CG1 . VAL C 1 186 ? -24.811 133.277 11.537 1.00 26.22 ? 238 VAL B CG1 1 ATOM 5236 C CG2 . VAL C 1 186 ? -26.963 133.593 10.233 1.00 27.35 ? 238 VAL B CG2 1 ATOM 5237 N N . THR C 1 187 ? -27.105 136.444 13.453 1.00 28.05 ? 239 THR B N 1 ATOM 5238 C CA . THR C 1 187 ? -27.870 136.386 14.695 1.00 33.84 ? 239 THR B CA 1 ATOM 5239 C C . THR C 1 187 ? -29.157 137.200 14.615 1.00 38.89 ? 239 THR B C 1 ATOM 5240 O O . THR C 1 187 ? -29.423 137.882 13.624 1.00 32.31 ? 239 THR B O 1 ATOM 5241 C CB . THR C 1 187 ? -27.050 136.910 15.888 1.00 31.64 ? 239 THR B CB 1 ATOM 5242 O OG1 . THR C 1 187 ? -26.872 138.327 15.764 1.00 29.51 ? 239 THR B OG1 1 ATOM 5243 C CG2 . THR C 1 187 ? -25.689 136.219 15.957 1.00 33.47 ? 239 THR B CG2 1 ATOM 5244 N N . GLU C 1 188 ? -29.947 137.106 15.678 1.00 37.43 ? 240 GLU B N 1 ATOM 5245 C CA . GLU C 1 188 ? -31.146 137.916 15.855 1.00 37.39 ? 240 GLU B CA 1 ATOM 5246 C C . GLU C 1 188 ? -30.892 139.399 15.588 1.00 37.46 ? 240 GLU B C 1 ATOM 5247 O O . GLU C 1 188 ? -31.613 140.037 14.819 1.00 41.60 ? 240 GLU B O 1 ATOM 5248 C CB . GLU C 1 188 ? -31.671 137.746 17.279 1.00 42.48 ? 240 GLU B CB 1 ATOM 5249 C CG . GLU C 1 188 ? -33.112 137.314 17.391 1.00 49.42 ? 240 GLU B CG 1 ATOM 5250 C CD . GLU C 1 188 ? -33.500 137.040 18.830 1.00 50.87 ? 240 GLU B CD 1 ATOM 5251 O OE1 . GLU C 1 188 ? -32.701 137.378 19.730 1.00 54.64 ? 240 GLU B OE1 1 ATOM 5252 O OE2 . GLU C 1 188 ? -34.592 136.483 19.066 1.00 58.96 ? 240 GLU B OE2 1 ATOM 5253 N N . SER C 1 189 ? -29.861 139.939 16.231 1.00 35.30 ? 241 SER B N 1 ATOM 5254 C CA . SER C 1 189 ? -29.584 141.370 16.186 1.00 39.52 ? 241 SER B CA 1 ATOM 5255 C C . SER C 1 189 ? -28.815 141.776 14.934 1.00 41.06 ? 241 SER B C 1 ATOM 5256 O O . SER C 1 189 ? -28.850 142.938 14.529 1.00 39.48 ? 241 SER B O 1 ATOM 5257 C CB . SER C 1 189 ? -28.798 141.791 17.432 1.00 48.98 ? 241 SER B CB 1 ATOM 5258 O OG . SER C 1 189 ? -27.421 141.476 17.300 1.00 55.92 ? 241 SER B OG 1 ATOM 5259 N N . ASN C 1 190 ? -28.116 140.820 14.329 1.00 34.93 ? 242 ASN B N 1 ATOM 5260 C CA . ASN C 1 190 ? -27.324 141.087 13.135 1.00 32.68 ? 242 ASN B CA 1 ATOM 5261 C C . ASN C 1 190 ? -27.483 139.957 12.119 1.00 33.03 ? 242 ASN B C 1 ATOM 5262 O O . ASN C 1 190 ? -26.586 139.124 11.962 1.00 29.69 ? 242 ASN B O 1 ATOM 5263 C CB . ASN C 1 190 ? -25.856 141.274 13.508 1.00 29.03 ? 242 ASN B CB 1 ATOM 5264 C CG . ASN C 1 190 ? -25.008 141.742 12.338 1.00 34.50 ? 242 ASN B CG 1 ATOM 5265 O OD1 . ASN C 1 190 ? -25.508 142.373 11.407 1.00 43.69 ? 242 ASN B OD1 1 ATOM 5266 N ND2 . ASN C 1 190 ? -23.716 141.435 12.382 1.00 36.41 ? 242 ASN B ND2 1 ATOM 5267 N N . PRO C 1 191 ? -28.637 139.919 11.435 1.00 29.15 ? 243 PRO B N 1 ATOM 5268 C CA . PRO C 1 191 ? -28.941 138.848 10.480 1.00 27.39 ? 243 PRO B CA 1 ATOM 5269 C C . PRO C 1 191 ? -28.097 138.917 9.212 1.00 30.21 ? 243 PRO B C 1 ATOM 5270 O O . PRO C 1 191 ? -27.565 139.970 8.868 1.00 25.80 ? 243 PRO B O 1 ATOM 5271 C CB . PRO C 1 191 ? -30.415 139.079 10.153 1.00 27.89 ? 243 PRO B CB 1 ATOM 5272 C CG . PRO C 1 191 ? -30.613 140.540 10.361 1.00 33.97 ? 243 PRO B CG 1 ATOM 5273 C CD . PRO C 1 191 ? -29.733 140.902 11.518 1.00 31.52 ? 243 PRO B CD 1 ATOM 5274 N N . LEU C 1 192 ? -27.981 137.779 8.537 1.00 26.18 ? 244 LEU B N 1 ATOM 5275 C CA . LEU C 1 192 ? -27.307 137.700 7.250 1.00 23.26 ? 244 LEU B CA 1 ATOM 5276 C C . LEU C 1 192 ? -28.354 137.958 6.168 1.00 15.20 ? 244 LEU B C 1 ATOM 5277 O O . LEU C 1 192 ? -29.353 137.250 6.085 1.00 19.29 ? 244 LEU B O 1 ATOM 5278 C CB . LEU C 1 192 ? -26.641 136.329 7.087 1.00 20.26 ? 244 LEU B CB 1 ATOM 5279 C CG . LEU C 1 192 ? -25.826 136.062 5.822 1.00 19.85 ? 244 LEU B CG 1 ATOM 5280 C CD1 . LEU C 1 192 ? -24.668 137.013 5.699 1.00 19.32 ? 244 LEU B CD1 1 ATOM 5281 C CD2 . LEU C 1 192 ? -25.328 134.615 5.824 1.00 20.86 ? 244 LEU B CD2 1 ATOM 5282 N N . ARG C 1 193 ? -28.125 138.987 5.358 1.00 21.52 ? 245 ARG B N 1 ATOM 5283 C CA . ARG C 1 193 ? -29.139 139.487 4.429 1.00 23.60 ? 245 ARG B CA 1 ATOM 5284 C C . ARG C 1 193 ? -29.073 138.850 3.040 1.00 18.88 ? 245 ARG B C 1 ATOM 5285 O O . ARG C 1 193 ? -28.035 138.902 2.388 1.00 21.56 ? 245 ARG B O 1 ATOM 5286 C CB . ARG C 1 193 ? -28.997 141.002 4.256 1.00 26.54 ? 245 ARG B CB 1 ATOM 5287 C CG . ARG C 1 193 ? -28.949 141.813 5.540 1.00 33.18 ? 245 ARG B CG 1 ATOM 5288 C CD . ARG C 1 193 ? -30.329 142.208 5.995 1.00 35.79 ? 245 ARG B CD 1 ATOM 5289 N NE . ARG C 1 193 ? -30.271 143.074 7.168 1.00 36.82 ? 245 ARG B NE 1 ATOM 5290 C CZ . ARG C 1 193 ? -31.298 143.304 7.977 1.00 36.38 ? 245 ARG B CZ 1 ATOM 5291 N NH1 . ARG C 1 193 ? -31.147 144.106 9.023 1.00 38.25 ? 245 ARG B NH1 1 ATOM 5292 N NH2 . ARG C 1 193 ? -32.470 142.730 7.746 1.00 33.91 ? 245 ARG B NH2 1 ATOM 5293 N N . PHE C 1 194 ? -30.189 138.289 2.587 1.00 19.75 ? 246 PHE B N 1 ATOM 5294 C CA . PHE C 1 194 ? -30.328 137.843 1.197 1.00 20.07 ? 246 PHE B CA 1 ATOM 5295 C C . PHE C 1 194 ? -30.969 138.984 0.408 1.00 22.32 ? 246 PHE B C 1 ATOM 5296 O O . PHE C 1 194 ? -30.366 139.546 -0.509 1.00 21.86 ? 246 PHE B O 1 ATOM 5297 C CB . PHE C 1 194 ? -31.173 136.563 1.115 1.00 19.78 ? 246 PHE B CB 1 ATOM 5298 C CG . PHE C 1 194 ? -31.323 135.998 -0.285 1.00 16.13 ? 246 PHE B CG 1 ATOM 5299 C CD1 . PHE C 1 194 ? -30.402 136.286 -1.277 1.00 18.71 ? 246 PHE B CD1 1 ATOM 5300 C CD2 . PHE C 1 194 ? -32.388 135.165 -0.588 1.00 17.08 ? 246 PHE B CD2 1 ATOM 5301 C CE1 . PHE C 1 194 ? -30.551 135.757 -2.557 1.00 17.99 ? 246 PHE B CE1 1 ATOM 5302 C CE2 . PHE C 1 194 ? -32.542 134.629 -1.860 1.00 19.46 ? 246 PHE B CE2 1 ATOM 5303 C CZ . PHE C 1 194 ? -31.618 134.926 -2.844 1.00 19.52 ? 246 PHE B CZ 1 ATOM 5304 N N . LEU C 1 195 ? -32.197 139.322 0.791 1.00 21.48 ? 247 LEU B N 1 ATOM 5305 C CA . LEU C 1 195 ? -32.882 140.497 0.273 1.00 23.20 ? 247 LEU B CA 1 ATOM 5306 C C . LEU C 1 195 ? -32.887 141.552 1.367 1.00 25.35 ? 247 LEU B C 1 ATOM 5307 O O . LEU C 1 195 ? -33.637 141.448 2.343 1.00 26.72 ? 247 LEU B O 1 ATOM 5308 C CB . LEU C 1 195 ? -34.297 140.148 -0.168 1.00 21.34 ? 247 LEU B CB 1 ATOM 5309 C CG . LEU C 1 195 ? -34.414 138.867 -0.998 1.00 25.64 ? 247 LEU B CG 1 ATOM 5310 C CD1 . LEU C 1 195 ? -35.849 138.659 -1.437 1.00 26.28 ? 247 LEU B CD1 1 ATOM 5311 C CD2 . LEU C 1 195 ? -33.471 138.892 -2.202 1.00 23.91 ? 247 LEU B CD2 1 ATOM 5312 N N . ASP C 1 196 ? -32.023 142.547 1.213 1.00 22.93 ? 248 ASP B N 1 ATOM 5313 C CA . ASP C 1 196 ? -31.817 143.539 2.252 1.00 27.06 ? 248 ASP B CA 1 ATOM 5314 C C . ASP C 1 196 ? -32.912 144.583 2.175 1.00 32.92 ? 248 ASP B C 1 ATOM 5315 O O . ASP C 1 196 ? -32.799 145.579 1.462 1.00 28.92 ? 248 ASP B O 1 ATOM 5316 C CB . ASP C 1 196 ? -30.445 144.198 2.133 1.00 27.41 ? 248 ASP B CB 1 ATOM 5317 C CG . ASP C 1 196 ? -30.109 145.043 3.346 1.00 26.17 ? 248 ASP B CG 1 ATOM 5318 O OD1 . ASP C 1 196 ? -30.973 145.155 4.236 1.00 30.58 ? 248 ASP B OD1 1 ATOM 5319 O OD2 . ASP C 1 196 ? -28.997 145.593 3.413 1.00 28.85 ? 248 ASP B OD2 1 ATOM 5320 N N . THR C 1 197 ? -33.968 144.334 2.935 1.00 32.97 ? 249 THR B N 1 ATOM 5321 C CA . THR C 1 197 ? -35.119 145.217 2.987 1.00 35.71 ? 249 THR B CA 1 ATOM 5322 C C . THR C 1 197 ? -34.774 146.555 3.641 1.00 41.26 ? 249 THR B C 1 ATOM 5323 O O . THR C 1 197 ? -35.566 147.492 3.607 1.00 43.85 ? 249 THR B O 1 ATOM 5324 C CB . THR C 1 197 ? -36.266 144.557 3.764 1.00 33.71 ? 249 THR B CB 1 ATOM 5325 O OG1 . THR C 1 197 ? -35.860 144.333 5.120 1.00 41.28 ? 249 THR B OG1 1 ATOM 5326 C CG2 . THR C 1 197 ? -36.667 143.230 3.122 1.00 34.97 ? 249 THR B CG2 1 ATOM 5327 N N . THR C 1 198 ? -33.594 146.634 4.246 1.00 40.26 ? 250 THR B N 1 ATOM 5328 C CA . THR C 1 198 ? -33.126 147.860 4.881 1.00 37.50 ? 250 THR B CA 1 ATOM 5329 C C . THR C 1 198 ? -32.586 148.846 3.838 1.00 43.65 ? 250 THR B C 1 ATOM 5330 O O . THR C 1 198 ? -32.453 150.040 4.112 1.00 42.73 ? 250 THR B O 1 ATOM 5331 C CB . THR C 1 198 ? -32.043 147.534 5.939 1.00 40.32 ? 250 THR B CB 1 ATOM 5332 O OG1 . THR C 1 198 ? -32.643 146.789 7.005 1.00 47.03 ? 250 THR B OG1 1 ATOM 5333 C CG2 . THR C 1 198 ? -31.391 148.781 6.510 1.00 49.57 ? 250 THR B CG2 1 ATOM 5334 N N . GLN C 1 199 ? -32.311 148.345 2.636 1.00 38.77 ? 251 GLN B N 1 ATOM 5335 C CA . GLN C 1 199 ? -31.744 149.159 1.561 1.00 37.23 ? 251 GLN B CA 1 ATOM 5336 C C . GLN C 1 199 ? -32.657 149.172 0.346 1.00 36.67 ? 251 GLN B C 1 ATOM 5337 O O . GLN C 1 199 ? -32.488 148.380 -0.585 1.00 32.37 ? 251 GLN B O 1 ATOM 5338 C CB . GLN C 1 199 ? -30.362 148.638 1.172 1.00 35.79 ? 251 GLN B CB 1 ATOM 5339 C CG . GLN C 1 199 ? -29.246 149.102 2.090 1.00 46.65 ? 251 GLN B CG 1 ATOM 5340 C CD . GLN C 1 199 ? -27.938 148.393 1.809 1.00 49.44 ? 251 GLN B CD 1 ATOM 5341 O OE1 . GLN C 1 199 ? -27.819 147.656 0.830 1.00 43.40 ? 251 GLN B OE1 1 ATOM 5342 N NE2 . GLN C 1 199 ? -26.949 148.609 2.669 1.00 45.42 ? 251 GLN B NE2 1 ATOM 5343 N N . ARG C 1 200 ? -33.623 150.082 0.354 1.00 39.73 ? 252 ARG B N 1 ATOM 5344 C CA . ARG C 1 200 ? -34.595 150.156 -0.725 1.00 39.05 ? 252 ARG B CA 1 ATOM 5345 C C . ARG C 1 200 ? -33.964 150.717 -1.985 1.00 31.52 ? 252 ARG B C 1 ATOM 5346 O O . ARG C 1 200 ? -33.058 151.550 -1.929 1.00 41.33 ? 252 ARG B O 1 ATOM 5347 C CB . ARG C 1 200 ? -35.803 151.001 -0.305 1.00 51.56 ? 252 ARG B CB 1 ATOM 5348 C CG . ARG C 1 200 ? -36.750 150.240 0.595 1.00 55.90 ? 252 ARG B CG 1 ATOM 5349 C CD . ARG C 1 200 ? -37.779 151.122 1.284 1.00 64.74 ? 252 ARG B CD 1 ATOM 5350 N NE . ARG C 1 200 ? -38.439 152.027 0.344 1.00 68.77 ? 252 ARG B NE 1 ATOM 5351 C CZ . ARG C 1 200 ? -38.403 153.357 0.410 1.00 74.36 ? 252 ARG B CZ 1 ATOM 5352 N NH1 . ARG C 1 200 ? -39.036 154.076 -0.505 1.00 68.25 ? 252 ARG B NH1 1 ATOM 5353 N NH2 . ARG C 1 200 ? -37.748 153.979 1.385 1.00 74.34 ? 252 ARG B NH2 1 ATOM 5354 N N . GLN C 1 201 ? -34.450 150.233 -3.122 1.00 32.23 ? 253 GLN B N 1 ATOM 5355 C CA . GLN C 1 201 ? -33.961 150.651 -4.426 1.00 32.03 ? 253 GLN B CA 1 ATOM 5356 C C . GLN C 1 201 ? -35.107 151.207 -5.255 1.00 33.58 ? 253 GLN B C 1 ATOM 5357 O O . GLN C 1 201 ? -36.274 151.069 -4.888 1.00 30.43 ? 253 GLN B O 1 ATOM 5358 C CB . GLN C 1 201 ? -33.304 149.480 -5.150 1.00 35.19 ? 253 GLN B CB 1 ATOM 5359 C CG . GLN C 1 201 ? -32.056 148.963 -4.455 1.00 37.31 ? 253 GLN B CG 1 ATOM 5360 C CD . GLN C 1 201 ? -31.220 148.081 -5.356 1.00 39.56 ? 253 GLN B CD 1 ATOM 5361 O OE1 . GLN C 1 201 ? -31.710 147.099 -5.914 1.00 44.64 ? 253 GLN B OE1 1 ATOM 5362 N NE2 . GLN C 1 201 ? -29.951 148.436 -5.514 1.00 47.92 ? 253 GLN B NE2 1 ATOM 5363 N N . SER C 1 202 ? -34.767 151.830 -6.376 1.00 37.64 ? 254 SER B N 1 ATOM 5364 C CA . SER C 1 202 ? -35.766 152.464 -7.225 1.00 39.60 ? 254 SER B CA 1 ATOM 5365 C C . SER C 1 202 ? -36.647 151.429 -7.919 1.00 37.55 ? 254 SER B C 1 ATOM 5366 O O . SER C 1 202 ? -37.762 151.741 -8.335 1.00 28.12 ? 254 SER B O 1 ATOM 5367 C CB . SER C 1 202 ? -35.089 153.349 -8.269 1.00 28.33 ? 254 SER B CB 1 ATOM 5368 O OG . SER C 1 202 ? -34.448 152.555 -9.251 1.00 31.22 ? 254 SER B OG 1 ATOM 5369 N N . THR C 1 203 ? -36.147 150.200 -8.028 1.00 37.93 ? 255 THR B N 1 ATOM 5370 C CA . THR C 1 203 ? -36.819 149.161 -8.806 1.00 30.83 ? 255 THR B CA 1 ATOM 5371 C C . THR C 1 203 ? -37.425 148.052 -7.936 1.00 35.87 ? 255 THR B C 1 ATOM 5372 O O . THR C 1 203 ? -38.198 147.226 -8.425 1.00 30.51 ? 255 THR B O 1 ATOM 5373 C CB . THR C 1 203 ? -35.849 148.535 -9.826 1.00 35.83 ? 255 THR B CB 1 ATOM 5374 O OG1 . THR C 1 203 ? -36.473 147.412 -10.457 1.00 53.17 ? 255 THR B OG1 1 ATOM 5375 C CG2 . THR C 1 203 ? -34.566 148.085 -9.150 1.00 41.86 ? 255 THR B CG2 1 ATOM 5376 N N . GLN C 1 204 ? -37.082 148.038 -6.652 1.00 31.04 ? 256 GLN B N 1 ATOM 5377 C CA . GLN C 1 204 ? -37.684 147.097 -5.713 1.00 31.42 ? 256 GLN B CA 1 ATOM 5378 C C . GLN C 1 204 ? -37.363 147.516 -4.283 1.00 33.74 ? 256 GLN B C 1 ATOM 5379 O O . GLN C 1 204 ? -36.380 148.218 -4.044 1.00 30.31 ? 256 GLN B O 1 ATOM 5380 C CB . GLN C 1 204 ? -37.199 145.668 -5.977 1.00 35.81 ? 256 GLN B CB 1 ATOM 5381 C CG . GLN C 1 204 ? -35.789 145.371 -5.474 1.00 36.49 ? 256 GLN B CG 1 ATOM 5382 C CD . GLN C 1 204 ? -34.872 144.834 -6.555 1.00 46.59 ? 256 GLN B CD 1 ATOM 5383 O OE1 . GLN C 1 204 ? -35.015 145.163 -7.731 1.00 42.65 ? 256 GLN B OE1 1 ATOM 5384 N NE2 . GLN C 1 204 ? -33.919 143.997 -6.156 1.00 47.27 ? 256 GLN B NE2 1 ATOM 5385 N N . PRO C 1 205 ? -38.184 147.075 -3.320 1.00 32.33 ? 257 PRO B N 1 ATOM 5386 C CA . PRO C 1 205 ? -38.033 147.514 -1.929 1.00 40.39 ? 257 PRO B CA 1 ATOM 5387 C C . PRO C 1 205 ? -36.937 146.766 -1.164 1.00 39.83 ? 257 PRO B C 1 ATOM 5388 O O . PRO C 1 205 ? -37.048 146.564 0.047 1.00 37.70 ? 257 PRO B O 1 ATOM 5389 C CB . PRO C 1 205 ? -39.416 147.236 -1.334 1.00 38.31 ? 257 PRO B CB 1 ATOM 5390 C CG . PRO C 1 205 ? -39.941 146.128 -2.129 1.00 37.48 ? 257 PRO B CG 1 ATOM 5391 C CD . PRO C 1 205 ? -39.392 146.255 -3.509 1.00 37.54 ? 257 PRO B CD 1 ATOM 5392 N N . TYR C 1 206 ? -35.879 146.375 -1.868 1.00 34.85 ? 258 TYR B N 1 ATOM 5393 C CA . TYR C 1 206 ? -34.740 145.728 -1.230 1.00 29.06 ? 258 TYR B CA 1 ATOM 5394 C C . TYR C 1 206 ? -33.530 145.746 -2.151 1.00 27.23 ? 258 TYR B C 1 ATOM 5395 O O . TYR C 1 206 ? -33.650 146.026 -3.343 1.00 28.75 ? 258 TYR B O 1 ATOM 5396 C CB . TYR C 1 206 ? -35.082 144.286 -0.848 1.00 27.69 ? 258 TYR B CB 1 ATOM 5397 C CG . TYR C 1 206 ? -35.535 143.447 -2.017 1.00 29.72 ? 258 TYR B CG 1 ATOM 5398 C CD1 . TYR C 1 206 ? -34.612 142.800 -2.830 1.00 28.89 ? 258 TYR B CD1 1 ATOM 5399 C CD2 . TYR C 1 206 ? -36.883 143.299 -2.311 1.00 27.44 ? 258 TYR B CD2 1 ATOM 5400 C CE1 . TYR C 1 206 ? -35.019 142.037 -3.896 1.00 28.55 ? 258 TYR B CE1 1 ATOM 5401 C CE2 . TYR C 1 206 ? -37.299 142.536 -3.376 1.00 28.24 ? 258 TYR B CE2 1 ATOM 5402 C CZ . TYR C 1 206 ? -36.358 141.907 -4.169 1.00 28.81 ? 258 TYR B CZ 1 ATOM 5403 O OH . TYR C 1 206 ? -36.760 141.144 -5.235 1.00 36.95 ? 258 TYR B OH 1 ATOM 5404 N N . THR C 1 207 ? -32.366 145.457 -1.583 1.00 26.18 ? 259 THR B N 1 ATOM 5405 C CA . THR C 1 207 ? -31.159 145.236 -2.365 1.00 21.10 ? 259 THR B CA 1 ATOM 5406 C C . THR C 1 207 ? -30.831 143.750 -2.272 1.00 23.94 ? 259 THR B C 1 ATOM 5407 O O . THR C 1 207 ? -30.863 143.171 -1.184 1.00 22.12 ? 259 THR B O 1 ATOM 5408 C CB . THR C 1 207 ? -29.987 146.089 -1.869 1.00 24.04 ? 259 THR B CB 1 ATOM 5409 O OG1 . THR C 1 207 ? -30.313 147.481 -2.017 1.00 27.77 ? 259 THR B OG1 1 ATOM 5410 C CG2 . THR C 1 207 ? -28.726 145.791 -2.663 1.00 23.42 ? 259 THR B CG2 1 ATOM 5411 N N . GLU C 1 208 ? -30.560 143.136 -3.420 1.00 20.09 ? 260 GLU B N 1 ATOM 5412 C CA . GLU C 1 208 ? -30.261 141.710 -3.482 1.00 20.93 ? 260 GLU B CA 1 ATOM 5413 C C . GLU C 1 208 ? -28.795 141.441 -3.184 1.00 19.89 ? 260 GLU B C 1 ATOM 5414 O O . GLU C 1 208 ? -27.912 142.032 -3.794 1.00 18.10 ? 260 GLU B O 1 ATOM 5415 C CB . GLU C 1 208 ? -30.610 141.140 -4.858 1.00 19.49 ? 260 GLU B CB 1 ATOM 5416 C CG . GLU C 1 208 ? -30.313 139.648 -4.973 1.00 21.90 ? 260 GLU B CG 1 ATOM 5417 C CD . GLU C 1 208 ? -30.529 139.102 -6.368 1.00 32.71 ? 260 GLU B CD 1 ATOM 5418 O OE1 . GLU C 1 208 ? -31.159 139.797 -7.196 1.00 26.62 ? 260 GLU B OE1 1 ATOM 5419 O OE2 . GLU C 1 208 ? -30.065 137.970 -6.633 1.00 26.95 ? 260 GLU B OE2 1 ATOM 5420 N N . TYR C 1 209 ? -28.555 140.532 -2.245 1.00 19.13 ? 261 TYR B N 1 ATOM 5421 C CA . TYR C 1 209 ? -27.213 140.053 -1.947 1.00 19.85 ? 261 TYR B CA 1 ATOM 5422 C C . TYR C 1 209 ? -27.238 138.522 -2.024 1.00 18.28 ? 261 TYR B C 1 ATOM 5423 O O . TYR C 1 209 ? -27.864 137.960 -2.923 1.00 17.24 ? 261 TYR B O 1 ATOM 5424 C CB . TYR C 1 209 ? -26.747 140.557 -0.573 1.00 20.21 ? 261 TYR B CB 1 ATOM 5425 C CG . TYR C 1 209 ? -26.578 142.069 -0.496 1.00 19.86 ? 261 TYR B CG 1 ATOM 5426 C CD1 . TYR C 1 209 ? -25.529 142.701 -1.148 1.00 20.01 ? 261 TYR B CD1 1 ATOM 5427 C CD2 . TYR C 1 209 ? -27.463 142.853 0.235 1.00 22.59 ? 261 TYR B CD2 1 ATOM 5428 C CE1 . TYR C 1 209 ? -25.359 144.073 -1.083 1.00 29.87 ? 261 TYR B CE1 1 ATOM 5429 C CE2 . TYR C 1 209 ? -27.300 144.235 0.308 1.00 22.99 ? 261 TYR B CE2 1 ATOM 5430 C CZ . TYR C 1 209 ? -26.245 144.834 -0.354 1.00 26.25 ? 261 TYR B CZ 1 ATOM 5431 O OH . TYR C 1 209 ? -26.059 146.200 -0.300 1.00 28.57 ? 261 TYR B OH 1 ATOM 5432 N N . ALA C 1 210 ? -26.588 137.862 -1.067 1.00 18.87 ? 262 ALA B N 1 ATOM 5433 C CA . ALA C 1 210 ? -26.463 136.403 -1.050 1.00 14.59 ? 262 ALA B CA 1 ATOM 5434 C C . ALA C 1 210 ? -25.871 135.994 0.289 1.00 15.87 ? 262 ALA B C 1 ATOM 5435 O O . ALA C 1 210 ? -25.182 136.790 0.920 1.00 18.72 ? 262 ALA B O 1 ATOM 5436 C CB . ALA C 1 210 ? -25.579 135.920 -2.189 1.00 17.85 ? 262 ALA B CB 1 ATOM 5437 N N . PHE C 1 211 ? -26.147 134.764 0.723 1.00 13.88 ? 263 PHE B N 1 ATOM 5438 C CA . PHE C 1 211 ? -25.553 134.232 1.950 1.00 16.71 ? 263 PHE B CA 1 ATOM 5439 C C . PHE C 1 211 ? -24.085 133.849 1.753 1.00 18.36 ? 263 PHE B C 1 ATOM 5440 O O . PHE C 1 211 ? -23.351 133.679 2.728 1.00 18.85 ? 263 PHE B O 1 ATOM 5441 C CB . PHE C 1 211 ? -26.316 133.006 2.442 1.00 17.95 ? 263 PHE B CB 1 ATOM 5442 C CG . PHE C 1 211 ? -27.698 133.292 2.973 1.00 14.97 ? 263 PHE B CG 1 ATOM 5443 C CD1 . PHE C 1 211 ? -28.125 134.589 3.242 1.00 18.67 ? 263 PHE B CD1 1 ATOM 5444 C CD2 . PHE C 1 211 ? -28.569 132.246 3.221 1.00 17.74 ? 263 PHE B CD2 1 ATOM 5445 C CE1 . PHE C 1 211 ? -29.397 134.813 3.742 1.00 16.22 ? 263 PHE B CE1 1 ATOM 5446 C CE2 . PHE C 1 211 ? -29.836 132.472 3.710 1.00 18.10 ? 263 PHE B CE2 1 ATOM 5447 C CZ . PHE C 1 211 ? -30.251 133.765 3.970 1.00 17.40 ? 263 PHE B CZ 1 ATOM 5448 N N . HIS C 1 212 ? -23.674 133.700 0.495 1.00 15.37 ? 264 HIS B N 1 ATOM 5449 C CA . HIS C 1 212 ? -22.307 133.334 0.141 1.00 18.27 ? 264 HIS B CA 1 ATOM 5450 C C . HIS C 1 212 ? -22.040 133.699 -1.316 1.00 14.59 ? 264 HIS B C 1 ATOM 5451 O O . HIS C 1 212 ? -22.987 133.901 -2.093 1.00 16.33 ? 264 HIS B O 1 ATOM 5452 C CB . HIS C 1 212 ? -22.082 131.833 0.361 1.00 14.10 ? 264 HIS B CB 1 ATOM 5453 C CG . HIS C 1 212 ? -22.891 130.969 -0.553 1.00 13.52 ? 264 HIS B CG 1 ATOM 5454 N ND1 . HIS C 1 212 ? -22.337 130.260 -1.599 1.00 12.31 ? 264 HIS B ND1 1 ATOM 5455 C CD2 . HIS C 1 212 ? -24.215 130.692 -0.570 1.00 14.70 ? 264 HIS B CD2 1 ATOM 5456 C CE1 . HIS C 1 212 ? -23.288 129.592 -2.225 1.00 12.78 ? 264 HIS B CE1 1 ATOM 5457 N NE2 . HIS C 1 212 ? -24.437 129.838 -1.623 1.00 14.14 ? 264 HIS B NE2 1 ATOM 5458 N N . GLY C 1 213 ? -20.764 133.787 -1.675 1.00 14.65 ? 265 GLY B N 1 ATOM 5459 C CA . GLY C 1 213 ? -20.350 134.082 -3.036 1.00 15.65 ? 265 GLY B CA 1 ATOM 5460 C C . GLY C 1 213 ? -20.207 135.570 -3.282 1.00 19.86 ? 265 GLY B C 1 ATOM 5461 O O . GLY C 1 213 ? -20.655 136.385 -2.469 1.00 18.67 ? 265 GLY B O 1 ATOM 5462 N N . LYS C 1 214 ? -19.572 135.921 -4.396 1.00 16.48 ? 266 LYS B N 1 ATOM 5463 C CA . LYS C 1 214 ? -19.398 137.319 -4.773 1.00 17.09 ? 266 LYS B CA 1 ATOM 5464 C C . LYS C 1 214 ? -20.177 137.692 -6.034 1.00 19.09 ? 266 LYS B C 1 ATOM 5465 O O . LYS C 1 214 ? -19.980 138.775 -6.588 1.00 20.39 ? 266 LYS B O 1 ATOM 5466 C CB . LYS C 1 214 ? -17.915 137.629 -4.956 1.00 19.76 ? 266 LYS B CB 1 ATOM 5467 C CG . LYS C 1 214 ? -17.167 137.654 -3.630 1.00 25.09 ? 266 LYS B CG 1 ATOM 5468 C CD . LYS C 1 214 ? -15.816 138.343 -3.739 1.00 22.67 ? 266 LYS B CD 1 ATOM 5469 C CE . LYS C 1 214 ? -15.240 138.624 -2.364 1.00 26.82 ? 266 LYS B CE 1 ATOM 5470 N NZ . LYS C 1 214 ? -13.973 139.403 -2.431 1.00 32.86 ? 266 LYS B NZ 1 ATOM 5471 N N . GLY C 1 215 ? -21.068 136.806 -6.473 1.00 15.36 ? 267 GLY B N 1 ATOM 5472 C CA . GLY C 1 215 ? -21.986 137.111 -7.559 1.00 15.16 ? 267 GLY B CA 1 ATOM 5473 C C . GLY C 1 215 ? -21.514 136.683 -8.938 1.00 15.78 ? 267 GLY B C 1 ATOM 5474 O O . GLY C 1 215 ? -20.333 136.381 -9.148 1.00 17.72 ? 267 GLY B O 1 ATOM 5475 N N . GLY C 1 216 ? -22.456 136.665 -9.880 1.00 15.75 ? 268 GLY B N 1 ATOM 5476 C CA . GLY C 1 216 ? -22.159 136.393 -11.276 1.00 14.94 ? 268 GLY B CA 1 ATOM 5477 C C . GLY C 1 216 ? -22.468 134.976 -11.726 1.00 15.92 ? 268 GLY B C 1 ATOM 5478 O O . GLY C 1 216 ? -22.184 134.627 -12.873 1.00 16.41 ? 268 GLY B O 1 ATOM 5479 N N . HIS C 1 217 ? -23.055 134.174 -10.844 1.00 15.32 ? 269 HIS B N 1 ATOM 5480 C CA . HIS C 1 217 ? -23.228 132.745 -11.108 1.00 13.74 ? 269 HIS B CA 1 ATOM 5481 C C . HIS C 1 217 ? -24.654 132.376 -11.476 1.00 13.47 ? 269 HIS B C 1 ATOM 5482 O O . HIS C 1 217 ? -25.603 133.061 -11.101 1.00 14.65 ? 269 HIS B O 1 ATOM 5483 C CB . HIS C 1 217 ? -22.796 131.931 -9.883 1.00 13.64 ? 269 HIS B CB 1 ATOM 5484 C CG . HIS C 1 217 ? -21.465 132.336 -9.338 1.00 13.35 ? 269 HIS B CG 1 ATOM 5485 N ND1 . HIS C 1 217 ? -20.289 132.146 -10.033 1.00 14.10 ? 269 HIS B ND1 1 ATOM 5486 C CD2 . HIS C 1 217 ? -21.123 132.932 -8.172 1.00 14.05 ? 269 HIS B CD2 1 ATOM 5487 C CE1 . HIS C 1 217 ? -19.280 132.609 -9.317 1.00 17.66 ? 269 HIS B CE1 1 ATOM 5488 N NE2 . HIS C 1 217 ? -19.758 133.085 -8.181 1.00 14.79 ? 269 HIS B NE2 1 ATOM 5489 N N . LYS C 1 218 ? -24.811 131.271 -12.191 1.00 12.73 ? 270 LYS B N 1 ATOM 5490 C CA . LYS C 1 218 ? -26.130 130.782 -12.562 1.00 12.88 ? 270 LYS B CA 1 ATOM 5491 C C . LYS C 1 218 ? -26.799 130.145 -11.353 1.00 15.23 ? 270 LYS B C 1 ATOM 5492 O O . LYS C 1 218 ? -26.317 129.137 -10.826 1.00 14.45 ? 270 LYS B O 1 ATOM 5493 C CB . LYS C 1 218 ? -26.032 129.771 -13.707 1.00 13.56 ? 270 LYS B CB 1 ATOM 5494 C CG . LYS C 1 218 ? -25.541 130.366 -15.019 1.00 18.06 ? 270 LYS B CG 1 ATOM 5495 C CD . LYS C 1 218 ? -25.560 129.305 -16.108 1.00 17.95 ? 270 LYS B CD 1 ATOM 5496 C CE . LYS C 1 218 ? -24.782 129.718 -17.352 1.00 23.47 ? 270 LYS B CE 1 ATOM 5497 N NZ . LYS C 1 218 ? -25.462 130.767 -18.156 1.00 23.72 ? 270 LYS B NZ 1 ATOM 5498 N N . GLY C 1 219 ? -27.910 130.733 -10.913 1.00 14.10 ? 271 GLY B N 1 ATOM 5499 C CA . GLY C 1 219 ? -28.608 130.245 -9.736 1.00 13.00 ? 271 GLY B CA 1 ATOM 5500 C C . GLY C 1 219 ? -30.108 130.162 -9.904 1.00 14.95 ? 271 GLY B C 1 ATOM 5501 O O . GLY C 1 219 ? -30.653 130.490 -10.960 1.00 14.12 ? 271 GLY B O 1 ATOM 5502 N N . TYR C 1 220 ? -30.784 129.713 -8.853 1.00 13.26 ? 272 TYR B N 1 ATOM 5503 C CA . TYR C 1 220 ? -32.230 129.582 -8.882 1.00 13.52 ? 272 TYR B CA 1 ATOM 5504 C C . TYR C 1 220 ? -32.897 130.956 -8.917 1.00 12.41 ? 272 TYR B C 1 ATOM 5505 O O . TYR C 1 220 ? -32.339 131.954 -8.457 1.00 14.42 ? 272 TYR B O 1 ATOM 5506 C CB . TYR C 1 220 ? -32.728 128.748 -7.690 1.00 14.28 ? 272 TYR B CB 1 ATOM 5507 C CG . TYR C 1 220 ? -33.006 129.454 -6.372 1.00 16.07 ? 272 TYR B CG 1 ATOM 5508 C CD1 . TYR C 1 220 ? -31.982 129.798 -5.498 1.00 14.65 ? 272 TYR B CD1 1 ATOM 5509 C CD2 . TYR C 1 220 ? -34.313 129.689 -5.965 1.00 17.50 ? 272 TYR B CD2 1 ATOM 5510 C CE1 . TYR C 1 220 ? -32.250 130.405 -4.274 1.00 16.18 ? 272 TYR B CE1 1 ATOM 5511 C CE2 . TYR C 1 220 ? -34.587 130.288 -4.748 1.00 15.83 ? 272 TYR B CE2 1 ATOM 5512 C CZ . TYR C 1 220 ? -33.557 130.647 -3.915 1.00 17.06 ? 272 TYR B CZ 1 ATOM 5513 O OH . TYR C 1 220 ? -33.850 131.241 -2.706 1.00 18.90 ? 272 TYR B OH 1 ATOM 5514 N N . ASP C 1 221 ? -34.086 130.976 -9.508 1.00 14.08 ? 273 ASP B N 1 ATOM 5515 C CA . ASP C 1 221 ? -34.886 132.186 -9.613 1.00 15.09 ? 273 ASP B CA 1 ATOM 5516 C C . ASP C 1 221 ? -35.673 132.372 -8.324 1.00 16.28 ? 273 ASP B C 1 ATOM 5517 O O . ASP C 1 221 ? -36.780 131.866 -8.196 1.00 17.75 ? 273 ASP B O 1 ATOM 5518 C CB . ASP C 1 221 ? -35.821 132.094 -10.823 1.00 15.49 ? 273 ASP B CB 1 ATOM 5519 C CG . ASP C 1 221 ? -36.680 133.326 -10.994 1.00 17.49 ? 273 ASP B CG 1 ATOM 5520 O OD1 . ASP C 1 221 ? -36.449 134.318 -10.271 1.00 17.87 ? 273 ASP B OD1 1 ATOM 5521 O OD2 . ASP C 1 221 ? -37.571 133.293 -11.872 1.00 18.96 ? 273 ASP B OD2 1 ATOM 5522 N N . TYR C 1 222 ? -35.082 133.093 -7.377 1.00 16.68 ? 274 TYR B N 1 ATOM 5523 C CA . TYR C 1 222 ? -35.709 133.317 -6.076 1.00 19.46 ? 274 TYR B CA 1 ATOM 5524 C C . TYR C 1 222 ? -36.963 134.172 -6.228 1.00 21.97 ? 274 TYR B C 1 ATOM 5525 O O . TYR C 1 222 ? -37.910 134.033 -5.456 1.00 20.63 ? 274 TYR B O 1 ATOM 5526 C CB . TYR C 1 222 ? -34.724 133.992 -5.110 1.00 19.17 ? 274 TYR B CB 1 ATOM 5527 C CG . TYR C 1 222 ? -34.567 135.485 -5.342 1.00 22.85 ? 274 TYR B CG 1 ATOM 5528 C CD1 . TYR C 1 222 ? -35.452 136.396 -4.770 1.00 26.79 ? 274 TYR B CD1 1 ATOM 5529 C CD2 . TYR C 1 222 ? -33.551 135.984 -6.144 1.00 22.30 ? 274 TYR B CD2 1 ATOM 5530 C CE1 . TYR C 1 222 ? -35.325 137.754 -4.995 1.00 27.14 ? 274 TYR B CE1 1 ATOM 5531 C CE2 . TYR C 1 222 ? -33.415 137.341 -6.371 1.00 24.88 ? 274 TYR B CE2 1 ATOM 5532 C CZ . TYR C 1 222 ? -34.303 138.222 -5.793 1.00 28.70 ? 274 TYR B CZ 1 ATOM 5533 O OH . TYR C 1 222 ? -34.170 139.574 -6.018 1.00 32.61 ? 274 TYR B OH 1 ATOM 5534 N N . LYS C 1 223 ? -36.966 135.045 -7.231 1.00 19.76 ? 275 LYS B N 1 ATOM 5535 C CA . LYS C 1 223 ? -38.021 136.053 -7.356 1.00 19.40 ? 275 LYS B CA 1 ATOM 5536 C C . LYS C 1 223 ? -39.264 135.525 -8.065 1.00 20.18 ? 275 LYS B C 1 ATOM 5537 O O . LYS C 1 223 ? -40.390 135.744 -7.603 1.00 20.95 ? 275 LYS B O 1 ATOM 5538 C CB . LYS C 1 223 ? -37.493 137.283 -8.092 1.00 20.01 ? 275 LYS B CB 1 ATOM 5539 C CG . LYS C 1 223 ? -38.503 138.421 -8.187 1.00 25.67 ? 275 LYS B CG 1 ATOM 5540 C CD . LYS C 1 223 ? -37.983 139.566 -9.032 1.00 26.23 ? 275 LYS B CD 1 ATOM 5541 C CE . LYS C 1 223 ? -39.098 140.546 -9.378 1.00 33.04 ? 275 LYS B CE 1 ATOM 5542 N NZ . LYS C 1 223 ? -40.117 139.938 -10.293 1.00 30.81 ? 275 LYS B NZ 1 ATOM 5543 N N . GLY C 1 224 ? -39.068 134.835 -9.185 1.00 19.01 ? 276 GLY B N 1 ATOM 5544 C CA . GLY C 1 224 ? -40.168 134.442 -10.046 1.00 16.33 ? 276 GLY B CA 1 ATOM 5545 C C . GLY C 1 224 ? -40.618 135.628 -10.891 1.00 17.03 ? 276 GLY B C 1 ATOM 5546 O O . GLY C 1 224 ? -40.078 136.723 -10.778 1.00 20.40 ? 276 GLY B O 1 ATOM 5547 N N . GLN C 1 225 ? -41.625 135.415 -11.727 1.00 18.15 ? 277 GLN B N 1 ATOM 5548 C CA . GLN C 1 225 ? -42.041 136.446 -12.674 1.00 19.94 ? 277 GLN B CA 1 ATOM 5549 C C . GLN C 1 225 ? -43.222 137.314 -12.185 1.00 25.67 ? 277 GLN B C 1 ATOM 5550 O O . GLN C 1 225 ? -43.972 137.851 -13.007 1.00 24.27 ? 277 GLN B O 1 ATOM 5551 C CB . GLN C 1 225 ? -42.361 135.774 -14.013 1.00 20.73 ? 277 GLN B CB 1 ATOM 5552 C CG . GLN C 1 225 ? -41.137 135.121 -14.657 1.00 21.80 ? 277 GLN B CG 1 ATOM 5553 C CD . GLN C 1 225 ? -41.451 134.507 -16.000 1.00 25.75 ? 277 GLN B CD 1 ATOM 5554 O OE1 . GLN C 1 225 ? -42.212 133.548 -16.095 1.00 32.70 ? 277 GLN B OE1 1 ATOM 5555 N NE2 . GLN C 1 225 ? -40.878 135.070 -17.055 1.00 27.26 ? 277 GLN B NE2 1 ATOM 5556 N N . THR C 1 226 ? -43.341 137.476 -10.860 1.00 28.04 ? 278 THR B N 1 ATOM 5557 C CA . THR C 1 226 ? -44.294 138.413 -10.216 1.00 19.54 ? 278 THR B CA 1 ATOM 5558 C C . THR C 1 226 ? -43.585 139.303 -9.189 1.00 20.31 ? 278 THR B C 1 ATOM 5559 O O . THR C 1 226 ? -42.436 139.037 -8.815 1.00 28.96 ? 278 THR B O 1 ATOM 5560 C CB . THR C 1 226 ? -45.442 137.679 -9.469 1.00 32.91 ? 278 THR B CB 1 ATOM 5561 O OG1 . THR C 1 226 ? -45.045 137.419 -8.115 1.00 27.79 ? 278 THR B OG1 1 ATOM 5562 C CG2 . THR C 1 226 ? -45.817 136.366 -10.142 1.00 19.82 ? 278 THR B CG2 1 ATOM 5563 N N . SER C 1 227 ? -44.268 140.344 -8.704 1.00 26.19 ? 279 SER B N 1 ATOM 5564 C CA . SER C 1 227 ? -43.716 141.172 -7.624 1.00 29.94 ? 279 SER B CA 1 ATOM 5565 C C . SER C 1 227 ? -43.911 140.481 -6.275 1.00 32.36 ? 279 SER B C 1 ATOM 5566 O O . SER C 1 227 ? -43.330 140.896 -5.266 1.00 28.52 ? 279 SER B O 1 ATOM 5567 C CB . SER C 1 227 ? -44.354 142.572 -7.603 1.00 27.35 ? 279 SER B CB 1 ATOM 5568 O OG . SER C 1 227 ? -45.713 142.538 -7.185 1.00 23.20 ? 279 SER B OG 1 ATOM 5569 N N . HIS C 1 228 ? -44.733 139.433 -6.260 1.00 32.39 ? 280 HIS B N 1 ATOM 5570 C CA . HIS C 1 228 ? -44.855 138.573 -5.089 1.00 31.12 ? 280 HIS B CA 1 ATOM 5571 C C . HIS C 1 228 ? -43.638 137.668 -5.061 1.00 22.30 ? 280 HIS B C 1 ATOM 5572 O O . HIS C 1 228 ? -43.683 136.552 -5.577 1.00 25.38 ? 280 HIS B O 1 ATOM 5573 C CB . HIS C 1 228 ? -46.146 137.746 -5.129 1.00 29.79 ? 280 HIS B CB 1 ATOM 5574 C CG . HIS C 1 228 ? -46.495 137.109 -3.819 1.00 23.69 ? 280 HIS B CG 1 ATOM 5575 N ND1 . HIS C 1 228 ? -47.674 136.425 -3.616 1.00 26.60 ? 280 HIS B ND1 1 ATOM 5576 C CD2 . HIS C 1 228 ? -45.829 137.066 -2.641 1.00 24.88 ? 280 HIS B CD2 1 ATOM 5577 C CE1 . HIS C 1 228 ? -47.715 135.980 -2.374 1.00 21.68 ? 280 HIS B CE1 1 ATOM 5578 N NE2 . HIS C 1 228 ? -46.608 136.356 -1.760 1.00 22.97 ? 280 HIS B NE2 1 ATOM 5579 N N . VAL C 1 229 ? -42.557 138.167 -4.473 1.00 29.39 ? 281 VAL B N 1 ATOM 5580 C CA . VAL C 1 229 ? -41.269 137.489 -4.512 1.00 24.32 ? 281 VAL B CA 1 ATOM 5581 C C . VAL C 1 229 ? -41.410 136.044 -4.027 1.00 32.07 ? 281 VAL B C 1 ATOM 5582 O O . VAL C 1 229 ? -41.944 135.792 -2.947 1.00 28.52 ? 281 VAL B O 1 ATOM 5583 C CB . VAL C 1 229 ? -40.220 138.239 -3.661 1.00 26.52 ? 281 VAL B CB 1 ATOM 5584 C CG1 . VAL C 1 229 ? -38.899 137.485 -3.610 1.00 30.10 ? 281 VAL B CG1 1 ATOM 5585 C CG2 . VAL C 1 229 ? -40.000 139.655 -4.214 1.00 33.22 ? 281 VAL B CG2 1 ATOM 5586 N N . GLY C 1 230 ? -40.964 135.104 -4.858 1.00 22.42 ? 282 GLY B N 1 ATOM 5587 C CA . GLY C 1 230 ? -40.945 133.698 -4.496 1.00 21.09 ? 282 GLY B CA 1 ATOM 5588 C C . GLY C 1 230 ? -41.993 132.846 -5.179 1.00 20.60 ? 282 GLY B C 1 ATOM 5589 O O . GLY C 1 230 ? -41.958 131.622 -5.070 1.00 21.22 ? 282 GLY B O 1 ATOM 5590 N N . CYS C 1 231 ? -42.919 133.473 -5.894 1.00 20.75 ? 283 CYS B N 1 ATOM 5591 C CA . CYS C 1 231 ? -44.043 132.746 -6.456 1.00 20.95 ? 283 CYS B CA 1 ATOM 5592 C C . CYS C 1 231 ? -43.860 132.402 -7.940 1.00 20.56 ? 283 CYS B C 1 ATOM 5593 O O . CYS C 1 231 ? -43.158 133.110 -8.667 1.00 21.71 ? 283 CYS B O 1 ATOM 5594 C CB . CYS C 1 231 ? -45.325 133.552 -6.255 1.00 26.51 ? 283 CYS B CB 1 ATOM 5595 S SG . CYS C 1 231 ? -45.760 133.805 -4.506 1.00 26.43 ? 283 CYS B SG 1 ATOM 5596 N N . PRO C 1 232 ? -44.482 131.302 -8.390 1.00 19.41 ? 284 PRO B N 1 ATOM 5597 C CA . PRO C 1 232 ? -44.358 130.875 -9.789 1.00 21.10 ? 284 PRO B CA 1 ATOM 5598 C C . PRO C 1 232 ? -45.116 131.796 -10.745 1.00 27.74 ? 284 PRO B C 1 ATOM 5599 O O . PRO C 1 232 ? -45.975 132.557 -10.290 1.00 27.36 ? 284 PRO B O 1 ATOM 5600 C CB . PRO C 1 232 ? -44.949 129.462 -9.782 1.00 27.97 ? 284 PRO B CB 1 ATOM 5601 C CG . PRO C 1 232 ? -45.849 129.423 -8.595 1.00 26.27 ? 284 PRO B CG 1 ATOM 5602 C CD . PRO C 1 232 ? -45.253 130.338 -7.582 1.00 23.35 ? 284 PRO B CD 1 ATOM 5603 N N . PRO C 1 233 ? -44.797 131.742 -12.050 1.00 26.71 ? 285 PRO B N 1 ATOM 5604 C CA . PRO C 1 233 ? -43.799 130.872 -12.684 1.00 23.85 ? 285 PRO B CA 1 ATOM 5605 C C . PRO C 1 233 ? -42.369 131.393 -12.532 1.00 19.69 ? 285 PRO B C 1 ATOM 5606 O O . PRO C 1 233 ? -42.176 132.550 -12.179 1.00 19.37 ? 285 PRO B O 1 ATOM 5607 C CB . PRO C 1 233 ? -44.220 130.883 -14.152 1.00 29.03 ? 285 PRO B CB 1 ATOM 5608 C CG . PRO C 1 233 ? -44.808 132.235 -14.346 1.00 26.01 ? 285 PRO B CG 1 ATOM 5609 C CD . PRO C 1 233 ? -45.476 132.600 -13.041 1.00 27.88 ? 285 PRO B CD 1 ATOM 5610 N N . TYR C 1 234 ? -41.386 130.538 -12.807 1.00 19.51 ? 286 TYR B N 1 ATOM 5611 C CA . TYR C 1 234 ? -39.980 130.904 -12.648 1.00 16.97 ? 286 TYR B CA 1 ATOM 5612 C C . TYR C 1 234 ? -39.256 130.906 -13.988 1.00 15.50 ? 286 TYR B C 1 ATOM 5613 O O . TYR C 1 234 ? -39.676 130.232 -14.923 1.00 20.73 ? 286 TYR B O 1 ATOM 5614 C CB . TYR C 1 234 ? -39.294 129.937 -11.679 1.00 14.66 ? 286 TYR B CB 1 ATOM 5615 C CG . TYR C 1 234 ? -40.029 129.833 -10.368 1.00 14.74 ? 286 TYR B CG 1 ATOM 5616 C CD1 . TYR C 1 234 ? -39.883 130.805 -9.390 1.00 15.52 ? 286 TYR B CD1 1 ATOM 5617 C CD2 . TYR C 1 234 ? -40.886 128.775 -10.121 1.00 17.19 ? 286 TYR B CD2 1 ATOM 5618 C CE1 . TYR C 1 234 ? -40.569 130.716 -8.186 1.00 16.69 ? 286 TYR B CE1 1 ATOM 5619 C CE2 . TYR C 1 234 ? -41.576 128.678 -8.925 1.00 17.52 ? 286 TYR B CE2 1 ATOM 5620 C CZ . TYR C 1 234 ? -41.418 129.653 -7.968 1.00 16.28 ? 286 TYR B CZ 1 ATOM 5621 O OH . TYR C 1 234 ? -42.121 129.545 -6.784 1.00 17.61 ? 286 TYR B OH 1 ATOM 5622 N N . ASN C 1 235 ? -38.175 131.672 -14.075 1.00 19.70 ? 287 ASN B N 1 ATOM 5623 C CA . ASN C 1 235 ? -37.360 131.697 -15.281 1.00 20.77 ? 287 ASN B CA 1 ATOM 5624 C C . ASN C 1 235 ? -35.874 131.589 -14.948 1.00 18.38 ? 287 ASN B C 1 ATOM 5625 O O . ASN C 1 235 ? -35.118 132.535 -15.159 1.00 19.03 ? 287 ASN B O 1 ATOM 5626 C CB . ASN C 1 235 ? -37.629 132.974 -16.083 1.00 24.25 ? 287 ASN B CB 1 ATOM 5627 C CG . ASN C 1 235 ? -36.963 132.952 -17.455 1.00 22.37 ? 287 ASN B CG 1 ATOM 5628 O OD1 . ASN C 1 235 ? -36.840 131.901 -18.076 1.00 32.22 ? 287 ASN B OD1 1 ATOM 5629 N ND2 . ASN C 1 235 ? -36.540 134.109 -17.923 1.00 39.76 ? 287 ASN B ND2 1 ATOM 5630 N N . PRO C 1 236 ? -35.458 130.435 -14.399 1.00 16.21 ? 288 PRO B N 1 ATOM 5631 C CA . PRO C 1 236 ? -34.029 130.219 -14.161 1.00 16.99 ? 288 PRO B CA 1 ATOM 5632 C C . PRO C 1 236 ? -33.279 130.022 -15.474 1.00 17.97 ? 288 PRO B C 1 ATOM 5633 O O . PRO C 1 236 ? -33.900 129.657 -16.473 1.00 18.60 ? 288 PRO B O 1 ATOM 5634 C CB . PRO C 1 236 ? -34.006 128.946 -13.312 1.00 16.60 ? 288 PRO B CB 1 ATOM 5635 C CG . PRO C 1 236 ? -35.221 128.211 -13.718 1.00 17.83 ? 288 PRO B CG 1 ATOM 5636 C CD . PRO C 1 236 ? -36.260 129.257 -14.028 1.00 18.31 ? 288 PRO B CD 1 ATOM 5637 N N . PRO C 1 237 ? -31.959 130.255 -15.478 1.00 14.25 ? 289 PRO B N 1 ATOM 5638 C CA . PRO C 1 237 ? -31.160 130.719 -14.338 1.00 16.19 ? 289 PRO B CA 1 ATOM 5639 C C . PRO C 1 237 ? -31.276 132.217 -14.066 1.00 17.29 ? 289 PRO B C 1 ATOM 5640 O O . PRO C 1 237 ? -31.529 133.026 -14.965 1.00 17.70 ? 289 PRO B O 1 ATOM 5641 C CB . PRO C 1 237 ? -29.720 130.368 -14.745 1.00 15.32 ? 289 PRO B CB 1 ATOM 5642 C CG . PRO C 1 237 ? -29.837 129.470 -15.929 1.00 25.63 ? 289 PRO B CG 1 ATOM 5643 C CD . PRO C 1 237 ? -31.104 129.873 -16.610 1.00 17.64 ? 289 PRO B CD 1 ATOM 5644 N N . HIS C 1 238 ? -31.086 132.562 -12.802 1.00 17.12 ? 290 HIS B N 1 ATOM 5645 C CA . HIS C 1 238 ? -30.983 133.938 -12.355 1.00 15.87 ? 290 HIS B CA 1 ATOM 5646 C C . HIS C 1 238 ? -29.526 134.161 -11.991 1.00 14.85 ? 290 HIS B C 1 ATOM 5647 O O . HIS C 1 238 ? -28.915 133.282 -11.384 1.00 18.84 ? 290 HIS B O 1 ATOM 5648 C CB . HIS C 1 238 ? -31.911 134.182 -11.158 1.00 20.11 ? 290 HIS B CB 1 ATOM 5649 C CG . HIS C 1 238 ? -31.597 135.429 -10.397 1.00 20.74 ? 290 HIS B CG 1 ATOM 5650 N ND1 . HIS C 1 238 ? -31.955 136.682 -10.844 1.00 24.92 ? 290 HIS B ND1 1 ATOM 5651 C CD2 . HIS C 1 238 ? -30.956 135.617 -9.220 1.00 20.52 ? 290 HIS B CD2 1 ATOM 5652 C CE1 . HIS C 1 238 ? -31.546 137.589 -9.975 1.00 27.12 ? 290 HIS B CE1 1 ATOM 5653 N NE2 . HIS C 1 238 ? -30.937 136.969 -8.980 1.00 23.80 ? 290 HIS B NE2 1 ATOM 5654 N N . VAL C 1 239 ? -28.944 135.290 -12.375 1.00 15.84 ? 291 VAL B N 1 ATOM 5655 C CA . VAL C 1 239 ? -27.541 135.522 -12.052 1.00 16.05 ? 291 VAL B CA 1 ATOM 5656 C C . VAL C 1 239 ? -27.438 136.063 -10.626 1.00 16.64 ? 291 VAL B C 1 ATOM 5657 O O . VAL C 1 239 ? -28.060 137.068 -10.264 1.00 17.68 ? 291 VAL B O 1 ATOM 5658 C CB . VAL C 1 239 ? -26.857 136.462 -13.066 1.00 18.41 ? 291 VAL B CB 1 ATOM 5659 C CG1 . VAL C 1 239 ? -25.449 136.825 -12.603 1.00 17.36 ? 291 VAL B CG1 1 ATOM 5660 C CG2 . VAL C 1 239 ? -26.777 135.769 -14.436 1.00 19.19 ? 291 VAL B CG2 1 ATOM 5661 N N . THR C 1 240 ? -26.661 135.364 -9.807 1.00 15.64 ? 292 THR B N 1 ATOM 5662 C CA . THR C 1 240 ? -26.535 135.705 -8.396 1.00 15.66 ? 292 THR B CA 1 ATOM 5663 C C . THR C 1 240 ? -25.821 137.033 -8.155 1.00 16.33 ? 292 THR B C 1 ATOM 5664 O O . THR C 1 240 ? -25.037 137.518 -8.984 1.00 14.99 ? 292 THR B O 1 ATOM 5665 C CB . THR C 1 240 ? -25.766 134.624 -7.618 1.00 13.73 ? 292 THR B CB 1 ATOM 5666 O OG1 . THR C 1 240 ? -24.401 134.582 -8.069 1.00 14.37 ? 292 THR B OG1 1 ATOM 5667 C CG2 . THR C 1 240 ? -26.430 133.263 -7.766 1.00 16.88 ? 292 THR B CG2 1 ATOM 5668 N N . LYS C 1 241 ? -26.105 137.610 -6.993 1.00 17.58 ? 293 LYS B N 1 ATOM 5669 C CA . LYS C 1 241 ? -25.363 138.747 -6.481 1.00 17.37 ? 293 LYS B CA 1 ATOM 5670 C C . LYS C 1 241 ? -24.377 138.255 -5.435 1.00 18.13 ? 293 LYS B C 1 ATOM 5671 O O . LYS C 1 241 ? -24.353 137.066 -5.116 1.00 18.56 ? 293 LYS B O 1 ATOM 5672 C CB . LYS C 1 241 ? -26.305 139.786 -5.873 1.00 19.06 ? 293 LYS B CB 1 ATOM 5673 C CG . LYS C 1 241 ? -27.357 140.302 -6.827 1.00 26.47 ? 293 LYS B CG 1 ATOM 5674 C CD . LYS C 1 241 ? -26.768 141.261 -7.829 1.00 26.83 ? 293 LYS B CD 1 ATOM 5675 C CE . LYS C 1 241 ? -27.601 141.282 -9.098 1.00 41.60 ? 293 LYS B CE 1 ATOM 5676 N NZ . LYS C 1 241 ? -29.074 141.254 -8.837 1.00 38.86 ? 293 LYS B NZ 1 ATOM 5677 N N . GLY C 1 242 ? -23.582 139.172 -4.902 1.00 19.09 ? 294 GLY B N 1 ATOM 5678 C CA . GLY C 1 242 ? -22.585 138.845 -3.897 1.00 18.83 ? 294 GLY B CA 1 ATOM 5679 C C . GLY C 1 242 ? -23.059 139.129 -2.485 1.00 20.97 ? 294 GLY B C 1 ATOM 5680 O O . GLY C 1 242 ? -24.090 139.778 -2.283 1.00 19.37 ? 294 GLY B O 1 ATOM 5681 N N . MET C 1 243 ? -22.311 138.626 -1.506 1.00 19.90 ? 295 MET B N 1 ATOM 5682 C CA . MET C 1 243 ? -22.583 138.914 -0.103 1.00 20.04 ? 295 MET B CA 1 ATOM 5683 C C . MET C 1 243 ? -22.548 140.415 0.140 1.00 17.97 ? 295 MET B C 1 ATOM 5684 O O . MET C 1 243 ? -21.780 141.133 -0.493 1.00 19.21 ? 295 MET B O 1 ATOM 5685 C CB . MET C 1 243 ? -21.554 138.243 0.811 1.00 21.95 ? 295 MET B CB 1 ATOM 5686 C CG . MET C 1 243 ? -21.536 136.731 0.767 1.00 20.08 ? 295 MET B CG 1 ATOM 5687 S SD . MET C 1 243 ? -20.190 136.076 1.774 1.00 21.32 ? 295 MET B SD 1 ATOM 5688 C CE . MET C 1 243 ? -20.843 136.351 3.410 1.00 21.74 ? 295 MET B CE 1 ATOM 5689 N N . LYS C 1 244 ? -23.355 140.870 1.089 1.00 21.12 ? 296 LYS B N 1 ATOM 5690 C CA . LYS C 1 244 ? -23.329 142.269 1.500 1.00 21.87 ? 296 LYS B CA 1 ATOM 5691 C C . LYS C 1 244 ? -21.965 142.617 2.081 1.00 24.55 ? 296 LYS B C 1 ATOM 5692 O O . LYS C 1 244 ? -21.393 143.662 1.773 1.00 22.29 ? 296 LYS B O 1 ATOM 5693 C CB . LYS C 1 244 ? -24.437 142.545 2.516 1.00 23.35 ? 296 LYS B CB 1 ATOM 5694 C CG . LYS C 1 244 ? -24.544 144.007 2.951 1.00 23.44 ? 296 LYS B CG 1 ATOM 5695 C CD . LYS C 1 244 ? -25.768 144.224 3.818 1.00 28.92 ? 296 LYS B CD 1 ATOM 5696 C CE . LYS C 1 244 ? -25.834 145.651 4.349 1.00 35.71 ? 296 LYS B CE 1 ATOM 5697 N NZ . LYS C 1 244 ? -27.027 145.848 5.217 1.00 33.83 ? 296 LYS B NZ 1 ATOM 5698 N N . ASP C 1 245 ? -21.429 141.726 2.909 1.00 24.24 ? 297 ASP B N 1 ATOM 5699 C CA . ASP C 1 245 ? -20.115 141.952 3.498 1.00 21.53 ? 297 ASP B CA 1 ATOM 5700 C C . ASP C 1 245 ? -19.302 140.667 3.591 1.00 23.93 ? 297 ASP B C 1 ATOM 5701 O O . ASP C 1 245 ? -19.579 139.807 4.424 1.00 23.74 ? 297 ASP B O 1 ATOM 5702 C CB . ASP C 1 245 ? -20.243 142.566 4.890 1.00 24.30 ? 297 ASP B CB 1 ATOM 5703 C CG . ASP C 1 245 ? -18.896 142.837 5.522 1.00 26.62 ? 297 ASP B CG 1 ATOM 5704 O OD1 . ASP C 1 245 ? -17.918 143.042 4.772 1.00 24.14 ? 297 ASP B OD1 1 ATOM 5705 O OD2 . ASP C 1 245 ? -18.816 142.842 6.768 1.00 45.38 ? 297 ASP B OD2 1 ATOM 5706 N N . SER C 1 246 ? -18.290 140.565 2.736 1.00 22.66 ? 298 SER B N 1 ATOM 5707 C CA . SER C 1 246 ? -17.415 139.396 2.704 1.00 22.77 ? 298 SER B CA 1 ATOM 5708 C C . SER C 1 246 ? -16.030 139.729 3.258 1.00 28.09 ? 298 SER B C 1 ATOM 5709 O O . SER C 1 246 ? -15.138 138.886 3.256 1.00 26.96 ? 298 SER B O 1 ATOM 5710 C CB . SER C 1 246 ? -17.299 138.870 1.268 1.00 25.01 ? 298 SER B CB 1 ATOM 5711 O OG . SER C 1 246 ? -16.572 137.654 1.219 1.00 32.17 ? 298 SER B OG 1 ATOM 5712 N N . SER C 1 247 ? -15.858 140.955 3.752 1.00 23.98 ? 299 SER B N 1 ATOM 5713 C CA . SER C 1 247 ? -14.529 141.473 4.071 1.00 24.10 ? 299 SER B CA 1 ATOM 5714 C C . SER C 1 247 ? -13.824 140.728 5.211 1.00 21.06 ? 299 SER B C 1 ATOM 5715 O O . SER C 1 247 ? -12.598 140.718 5.274 1.00 25.22 ? 299 SER B O 1 ATOM 5716 C CB . SER C 1 247 ? -14.620 142.962 4.421 1.00 27.90 ? 299 SER B CB 1 ATOM 5717 O OG . SER C 1 247 ? -15.335 143.156 5.626 1.00 29.27 ? 299 SER B OG 1 ATOM 5718 N N . TRP C 1 248 ? -14.590 140.102 6.099 1.00 23.43 ? 300 TRP B N 1 ATOM 5719 C CA . TRP C 1 248 ? -14.000 139.364 7.212 1.00 21.44 ? 300 TRP B CA 1 ATOM 5720 C C . TRP C 1 248 ? -13.517 137.978 6.786 1.00 23.13 ? 300 TRP B C 1 ATOM 5721 O O . TRP C 1 248 ? -12.794 137.315 7.532 1.00 23.41 ? 300 TRP B O 1 ATOM 5722 C CB . TRP C 1 248 ? -14.998 139.230 8.356 1.00 24.10 ? 300 TRP B CB 1 ATOM 5723 C CG . TRP C 1 248 ? -16.243 138.467 8.011 1.00 25.46 ? 300 TRP B CG 1 ATOM 5724 C CD1 . TRP C 1 248 ? -17.415 138.984 7.539 1.00 25.18 ? 300 TRP B CD1 1 ATOM 5725 C CD2 . TRP C 1 248 ? -16.445 137.050 8.117 1.00 22.92 ? 300 TRP B CD2 1 ATOM 5726 N NE1 . TRP C 1 248 ? -18.333 137.983 7.348 1.00 27.67 ? 300 TRP B NE1 1 ATOM 5727 C CE2 . TRP C 1 248 ? -17.764 136.786 7.694 1.00 23.54 ? 300 TRP B CE2 1 ATOM 5728 C CE3 . TRP C 1 248 ? -15.641 135.981 8.529 1.00 22.64 ? 300 TRP B CE3 1 ATOM 5729 C CZ2 . TRP C 1 248 ? -18.296 135.501 7.668 1.00 22.57 ? 300 TRP B CZ2 1 ATOM 5730 C CZ3 . TRP C 1 248 ? -16.174 134.704 8.502 1.00 21.25 ? 300 TRP B CZ3 1 ATOM 5731 C CH2 . TRP C 1 248 ? -17.488 134.475 8.078 1.00 19.12 ? 300 TRP B CH2 1 ATOM 5732 N N . ILE C 1 249 ? -13.910 137.548 5.591 1.00 22.78 ? 301 ILE B N 1 ATOM 5733 C CA . ILE C 1 249 ? -13.469 136.252 5.070 1.00 19.96 ? 301 ILE B CA 1 ATOM 5734 C C . ILE C 1 249 ? -12.125 136.427 4.376 1.00 17.24 ? 301 ILE B C 1 ATOM 5735 O O . ILE C 1 249 ? -12.048 136.613 3.163 1.00 20.88 ? 301 ILE B O 1 ATOM 5736 C CB . ILE C 1 249 ? -14.494 135.644 4.104 1.00 18.70 ? 301 ILE B CB 1 ATOM 5737 C CG1 . ILE C 1 249 ? -15.879 135.625 4.751 1.00 22.76 ? 301 ILE B CG1 1 ATOM 5738 C CG2 . ILE C 1 249 ? -14.058 134.220 3.719 1.00 18.26 ? 301 ILE B CG2 1 ATOM 5739 C CD1 . ILE C 1 249 ? -16.981 135.072 3.864 1.00 20.99 ? 301 ILE B CD1 1 ATOM 5740 N N . THR C 1 250 ? -11.058 136.370 5.164 1.00 20.13 ? 302 THR B N 1 ATOM 5741 C CA . THR C 1 250 ? -9.726 136.685 4.682 1.00 21.26 ? 302 THR B CA 1 ATOM 5742 C C . THR C 1 250 ? -8.924 135.459 4.234 1.00 21.27 ? 302 THR B C 1 ATOM 5743 O O . THR C 1 250 ? -7.879 135.594 3.603 1.00 24.08 ? 302 THR B O 1 ATOM 5744 C CB . THR C 1 250 ? -8.929 137.415 5.774 1.00 26.54 ? 302 THR B CB 1 ATOM 5745 O OG1 . THR C 1 250 ? -8.977 136.649 6.984 1.00 26.43 ? 302 THR B OG1 1 ATOM 5746 C CG2 . THR C 1 250 ? -9.528 138.799 6.036 1.00 32.80 ? 302 THR B CG2 1 ATOM 5747 N N . GLY C 1 251 ? -9.410 134.268 4.561 1.00 20.72 ? 303 GLY B N 1 ATOM 5748 C CA . GLY C 1 251 ? -8.685 133.054 4.238 1.00 20.74 ? 303 GLY B CA 1 ATOM 5749 C C . GLY C 1 251 ? -9.578 131.833 4.282 1.00 15.35 ? 303 GLY B C 1 ATOM 5750 O O . GLY C 1 251 ? -10.762 131.930 4.583 1.00 17.99 ? 303 GLY B O 1 ATOM 5751 N N . PRO C 1 252 ? -9.005 130.657 3.977 1.00 17.46 ? 304 PRO B N 1 ATOM 5752 C CA . PRO C 1 252 ? -9.740 129.388 3.988 1.00 16.58 ? 304 PRO B CA 1 ATOM 5753 C C . PRO C 1 252 ? -10.466 129.095 5.295 1.00 15.67 ? 304 PRO B C 1 ATOM 5754 O O . PRO C 1 252 ? -11.603 128.647 5.265 1.00 16.93 ? 304 PRO B O 1 ATOM 5755 C CB . PRO C 1 252 ? -8.642 128.344 3.751 1.00 19.00 ? 304 PRO B CB 1 ATOM 5756 C CG . PRO C 1 252 ? -7.579 129.061 3.037 1.00 21.71 ? 304 PRO B CG 1 ATOM 5757 C CD . PRO C 1 252 ? -7.622 130.499 3.506 1.00 18.52 ? 304 PRO B CD 1 ATOM 5758 N N . PHE C 1 253 ? -9.826 129.321 6.439 1.00 16.37 ? 305 PHE B N 1 ATOM 5759 C CA . PHE C 1 253 ? -10.499 129.026 7.696 1.00 16.20 ? 305 PHE B CA 1 ATOM 5760 C C . PHE C 1 253 ? -11.727 129.920 7.895 1.00 13.76 ? 305 PHE B C 1 ATOM 5761 O O . PHE C 1 253 ? -12.776 129.459 8.328 1.00 16.21 ? 305 PHE B O 1 ATOM 5762 C CB . PHE C 1 253 ? -9.555 129.181 8.893 1.00 19.26 ? 305 PHE B CB 1 ATOM 5763 C CG . PHE C 1 253 ? -10.257 129.051 10.198 1.00 18.97 ? 305 PHE B CG 1 ATOM 5764 C CD1 . PHE C 1 253 ? -10.842 127.849 10.564 1.00 17.23 ? 305 PHE B CD1 1 ATOM 5765 C CD2 . PHE C 1 253 ? -10.399 130.139 11.043 1.00 19.53 ? 305 PHE B CD2 1 ATOM 5766 C CE1 . PHE C 1 253 ? -11.528 127.726 11.749 1.00 17.25 ? 305 PHE B CE1 1 ATOM 5767 C CE2 . PHE C 1 253 ? -11.085 130.011 12.239 1.00 21.27 ? 305 PHE B CE2 1 ATOM 5768 C CZ . PHE C 1 253 ? -11.653 128.814 12.589 1.00 20.58 ? 305 PHE B CZ 1 ATOM 5769 N N . GLU C 1 254 ? -11.584 131.204 7.592 1.00 18.27 ? 306 GLU B N 1 ATOM 5770 C CA . GLU C 1 254 ? -12.699 132.121 7.730 1.00 20.14 ? 306 GLU B CA 1 ATOM 5771 C C . GLU C 1 254 ? -13.835 131.707 6.789 1.00 17.61 ? 306 GLU B C 1 ATOM 5772 O O . GLU C 1 254 ? -15.011 131.821 7.127 1.00 17.61 ? 306 GLU B O 1 ATOM 5773 C CB . GLU C 1 254 ? -12.230 133.552 7.460 1.00 19.69 ? 306 GLU B CB 1 ATOM 5774 C CG . GLU C 1 254 ? -11.278 134.107 8.543 1.00 22.23 ? 306 GLU B CG 1 ATOM 5775 C CD . GLU C 1 254 ? -9.842 133.600 8.448 1.00 28.88 ? 306 GLU B CD 1 ATOM 5776 O OE1 . GLU C 1 254 ? -9.464 132.978 7.431 1.00 23.55 ? 306 GLU B OE1 1 ATOM 5777 O OE2 . GLU C 1 254 ? -9.078 133.843 9.408 1.00 31.09 ? 306 GLU B OE2 1 ATOM 5778 N N . CYS C 1 255 ? -13.478 131.168 5.626 1.00 17.54 ? 307 CYS B N 1 ATOM 5779 C CA . CYS C 1 255 ? -14.486 130.625 4.722 1.00 15.98 ? 307 CYS B CA 1 ATOM 5780 C C . CYS C 1 255 ? -15.248 129.452 5.367 1.00 16.90 ? 307 CYS B C 1 ATOM 5781 O O . CYS C 1 255 ? -16.461 129.338 5.216 1.00 17.22 ? 307 CYS B O 1 ATOM 5782 C CB . CYS C 1 255 ? -13.829 130.196 3.405 1.00 18.67 ? 307 CYS B CB 1 ATOM 5783 S SG . CYS C 1 255 ? -14.990 129.643 2.125 1.00 21.28 ? 307 CYS B SG 1 ATOM 5784 N N . SER C 1 256 ? -14.546 128.582 6.097 1.00 15.25 ? 308 SER B N 1 ATOM 5785 C CA . SER C 1 256 ? -15.215 127.487 6.789 1.00 16.40 ? 308 SER B CA 1 ATOM 5786 C C . SER C 1 256 ? -16.186 128.000 7.852 1.00 14.35 ? 308 SER B C 1 ATOM 5787 O O . SER C 1 256 ? -17.195 127.364 8.117 1.00 15.98 ? 308 SER B O 1 ATOM 5788 C CB . SER C 1 256 ? -14.196 126.525 7.418 1.00 17.69 ? 308 SER B CB 1 ATOM 5789 O OG . SER C 1 256 ? -13.667 127.005 8.650 1.00 18.58 ? 308 SER B OG 1 ATOM 5790 N N . ILE C 1 257 ? -15.892 129.156 8.451 1.00 16.02 ? 309 ILE B N 1 ATOM 5791 C CA . ILE C 1 257 ? -16.795 129.724 9.455 1.00 17.78 ? 309 ILE B CA 1 ATOM 5792 C C . ILE C 1 257 ? -18.137 130.099 8.833 1.00 14.20 ? 309 ILE B C 1 ATOM 5793 O O . ILE C 1 257 ? -19.185 129.915 9.447 1.00 16.73 ? 309 ILE B O 1 ATOM 5794 C CB . ILE C 1 257 ? -16.168 130.954 10.140 1.00 17.70 ? 309 ILE B CB 1 ATOM 5795 C CG1 . ILE C 1 257 ? -14.984 130.508 11.008 1.00 20.11 ? 309 ILE B CG1 1 ATOM 5796 C CG2 . ILE C 1 257 ? -17.210 131.693 10.990 1.00 20.79 ? 309 ILE B CG2 1 ATOM 5797 C CD1 . ILE C 1 257 ? -14.231 131.643 11.656 1.00 21.44 ? 309 ILE B CD1 1 ATOM 5798 N N . LEU C 1 258 ? -18.109 130.602 7.603 1.00 16.92 ? 310 LEU B N 1 ATOM 5799 C CA . LEU C 1 258 ? -19.352 130.906 6.900 1.00 17.78 ? 310 LEU B CA 1 ATOM 5800 C C . LEU C 1 258 ? -20.221 129.657 6.796 1.00 16.53 ? 310 LEU B C 1 ATOM 5801 O O . LEU C 1 258 ? -21.421 129.708 7.033 1.00 16.31 ? 310 LEU B O 1 ATOM 5802 C CB . LEU C 1 258 ? -19.059 131.486 5.516 1.00 17.40 ? 310 LEU B CB 1 ATOM 5803 C CG . LEU C 1 258 ? -20.280 131.928 4.702 1.00 18.51 ? 310 LEU B CG 1 ATOM 5804 C CD1 . LEU C 1 258 ? -21.073 133.010 5.443 1.00 18.56 ? 310 LEU B CD1 1 ATOM 5805 C CD2 . LEU C 1 258 ? -19.849 132.418 3.329 1.00 18.15 ? 310 LEU B CD2 1 ATOM 5806 N N . SER C 1 259 ? -19.611 128.517 6.477 1.00 15.17 ? 311 SER B N 1 ATOM 5807 C CA . SER C 1 259 ? -20.343 127.261 6.458 1.00 14.48 ? 311 SER B CA 1 ATOM 5808 C C . SER C 1 259 ? -20.885 126.867 7.829 1.00 13.90 ? 311 SER B C 1 ATOM 5809 O O . SER C 1 259 ? -22.057 126.517 7.973 1.00 16.15 ? 311 SER B O 1 ATOM 5810 C CB . SER C 1 259 ? -19.455 126.131 5.939 1.00 13.59 ? 311 SER B CB 1 ATOM 5811 O OG . SER C 1 259 ? -20.078 124.896 6.199 1.00 16.59 ? 311 SER B OG 1 ATOM 5812 N N . ARG C 1 260 ? -20.007 126.891 8.824 1.00 15.68 ? 312 ARG B N 1 ATOM 5813 C CA . ARG C 1 260 ? -20.371 126.477 10.173 1.00 18.12 ? 312 ARG B CA 1 ATOM 5814 C C . ARG C 1 260 ? -21.625 127.187 10.660 1.00 14.73 ? 312 ARG B C 1 ATOM 5815 O O . ARG C 1 260 ? -22.507 126.582 11.261 1.00 16.54 ? 312 ARG B O 1 ATOM 5816 C CB . ARG C 1 260 ? -19.216 126.756 11.129 1.00 18.73 ? 312 ARG B CB 1 ATOM 5817 C CG . ARG C 1 260 ? -19.532 126.472 12.588 1.00 16.59 ? 312 ARG B CG 1 ATOM 5818 C CD . ARG C 1 260 ? -18.405 126.941 13.485 1.00 20.32 ? 312 ARG B CD 1 ATOM 5819 N NE . ARG C 1 260 ? -18.745 126.742 14.889 1.00 17.40 ? 312 ARG B NE 1 ATOM 5820 C CZ . ARG C 1 260 ? -17.922 126.979 15.904 1.00 19.96 ? 312 ARG B CZ 1 ATOM 5821 N NH1 . ARG C 1 260 ? -16.697 127.421 15.685 1.00 19.19 ? 312 ARG B NH1 1 ATOM 5822 N NH2 . ARG C 1 260 ? -18.333 126.767 17.149 1.00 22.32 ? 312 ARG B NH2 1 ATOM 5823 N N . CYS C 1 261 ? -21.709 128.473 10.357 1.00 19.75 ? 313 CYS B N 1 ATOM 5824 C CA . CYS C 1 261 ? -22.714 129.325 10.979 1.00 19.32 ? 313 CYS B CA 1 ATOM 5825 C C . CYS C 1 261 ? -24.054 129.384 10.241 1.00 21.52 ? 313 CYS B C 1 ATOM 5826 O O . CYS C 1 261 ? -25.049 129.848 10.804 1.00 21.70 ? 313 CYS B O 1 ATOM 5827 C CB . CYS C 1 261 ? -22.143 130.732 11.115 1.00 18.76 ? 313 CYS B CB 1 ATOM 5828 S SG . CYS C 1 261 ? -20.718 130.840 12.212 1.00 21.64 ? 313 CYS B SG 1 ATOM 5829 N N . THR C 1 262 ? -24.097 128.920 8.995 1.00 18.97 ? 314 THR B N 1 ATOM 5830 C CA . THR C 1 262 ? -25.293 129.100 8.165 1.00 18.27 ? 314 THR B CA 1 ATOM 5831 C C . THR C 1 262 ? -26.154 127.849 7.921 1.00 17.75 ? 314 THR B C 1 ATOM 5832 O O . THR C 1 262 ? -27.129 127.911 7.179 1.00 17.99 ? 314 THR B O 1 ATOM 5833 C CB . THR C 1 262 ? -24.899 129.696 6.791 1.00 17.74 ? 314 THR B CB 1 ATOM 5834 O OG1 . THR C 1 262 ? -23.895 128.880 6.165 1.00 19.73 ? 314 THR B OG1 1 ATOM 5835 C CG2 . THR C 1 262 ? -24.373 131.117 6.960 1.00 18.87 ? 314 THR B CG2 1 ATOM 5836 N N . THR C 1 263 ? -25.825 126.719 8.549 1.00 16.16 ? 315 THR B N 1 ATOM 5837 C CA . THR C 1 263 ? -26.634 125.516 8.432 1.00 18.58 ? 315 THR B CA 1 ATOM 5838 C C . THR C 1 263 ? -28.133 125.756 8.586 1.00 18.12 ? 315 THR B C 1 ATOM 5839 O O . THR C 1 263 ? -28.931 125.273 7.790 1.00 18.06 ? 315 THR B O 1 ATOM 5840 C CB . THR C 1 263 ? -26.182 124.481 9.478 1.00 19.03 ? 315 THR B CB 1 ATOM 5841 O OG1 . THR C 1 263 ? -24.926 123.925 9.057 1.00 19.04 ? 315 THR B OG1 1 ATOM 5842 C CG2 . THR C 1 263 ? -27.207 123.362 9.663 1.00 18.80 ? 315 THR B CG2 1 ATOM 5843 N N . HIS C 1 264 ? -28.522 126.503 9.611 1.00 20.84 ? 316 HIS B N 1 ATOM 5844 C CA . HIS C 1 264 ? -29.941 126.598 9.927 1.00 19.97 ? 316 HIS B CA 1 ATOM 5845 C C . HIS C 1 264 ? -30.670 127.624 9.072 1.00 22.58 ? 316 HIS B C 1 ATOM 5846 O O . HIS C 1 264 ? -31.890 127.770 9.176 1.00 22.23 ? 316 HIS B O 1 ATOM 5847 C CB . HIS C 1 264 ? -30.112 126.901 11.411 1.00 20.68 ? 316 HIS B CB 1 ATOM 5848 C CG . HIS C 1 264 ? -29.655 125.775 12.280 1.00 20.05 ? 316 HIS B CG 1 ATOM 5849 N ND1 . HIS C 1 264 ? -30.239 124.528 12.239 1.00 24.04 ? 316 HIS B ND1 1 ATOM 5850 C CD2 . HIS C 1 264 ? -28.638 125.690 13.168 1.00 23.42 ? 316 HIS B CD2 1 ATOM 5851 C CE1 . HIS C 1 264 ? -29.614 123.727 13.085 1.00 19.82 ? 316 HIS B CE1 1 ATOM 5852 N NE2 . HIS C 1 264 ? -28.642 124.408 13.661 1.00 18.61 ? 316 HIS B NE2 1 ATOM 5853 N N . CYS C 1 265 ? -29.925 128.302 8.206 1.00 18.97 ? 317 CYS B N 1 ATOM 5854 C CA . CYS C 1 265 ? -30.526 129.221 7.245 1.00 18.45 ? 317 CYS B CA 1 ATOM 5855 C C . CYS C 1 265 ? -31.275 128.486 6.141 1.00 20.06 ? 317 CYS B C 1 ATOM 5856 O O . CYS C 1 265 ? -32.091 129.084 5.449 1.00 20.82 ? 317 CYS B O 1 ATOM 5857 C CB . CYS C 1 265 ? -29.460 130.107 6.620 1.00 17.55 ? 317 CYS B CB 1 ATOM 5858 S SG . CYS C 1 265 ? -28.489 131.065 7.777 1.00 21.43 ? 317 CYS B SG 1 ATOM 5859 N N . TRP C 1 266 ? -30.979 127.200 5.958 1.00 17.79 ? 318 TRP B N 1 ATOM 5860 C CA . TRP C 1 266 ? -31.608 126.398 4.910 1.00 17.18 ? 318 TRP B CA 1 ATOM 5861 C C . TRP C 1 266 ? -32.796 125.584 5.421 1.00 19.55 ? 318 TRP B C 1 ATOM 5862 O O . TRP C 1 266 ? -32.767 125.076 6.545 1.00 20.56 ? 318 TRP B O 1 ATOM 5863 C CB . TRP C 1 266 ? -30.573 125.452 4.283 1.00 16.43 ? 318 TRP B CB 1 ATOM 5864 C CG . TRP C 1 266 ? -29.283 126.126 3.968 1.00 15.82 ? 318 TRP B CG 1 ATOM 5865 C CD1 . TRP C 1 266 ? -28.069 125.856 4.520 1.00 15.69 ? 318 TRP B CD1 1 ATOM 5866 C CD2 . TRP C 1 266 ? -29.066 127.191 3.030 1.00 14.85 ? 318 TRP B CD2 1 ATOM 5867 N NE1 . TRP C 1 266 ? -27.112 126.676 3.991 1.00 16.04 ? 318 TRP B NE1 1 ATOM 5868 C CE2 . TRP C 1 266 ? -27.697 127.510 3.075 1.00 15.23 ? 318 TRP B CE2 1 ATOM 5869 C CE3 . TRP C 1 266 ? -29.898 127.904 2.157 1.00 16.26 ? 318 TRP B CE3 1 ATOM 5870 C CZ2 . TRP C 1 266 ? -27.134 128.510 2.279 1.00 14.11 ? 318 TRP B CZ2 1 ATOM 5871 C CZ3 . TRP C 1 266 ? -29.333 128.898 1.363 1.00 15.12 ? 318 TRP B CZ3 1 ATOM 5872 C CH2 . TRP C 1 266 ? -27.971 129.191 1.431 1.00 14.86 ? 318 TRP B CH2 1 ATOM 5873 N N . PRO C 1 267 ? -33.845 125.436 4.593 1.00 19.03 ? 319 PRO B N 1 ATOM 5874 C CA . PRO C 1 267 ? -35.018 124.683 5.041 1.00 18.66 ? 319 PRO B CA 1 ATOM 5875 C C . PRO C 1 267 ? -34.775 123.178 5.040 1.00 22.07 ? 319 PRO B C 1 ATOM 5876 O O . PRO C 1 267 ? -34.084 122.663 4.156 1.00 19.93 ? 319 PRO B O 1 ATOM 5877 C CB . PRO C 1 267 ? -36.085 125.064 4.013 1.00 20.50 ? 319 PRO B CB 1 ATOM 5878 C CG . PRO C 1 267 ? -35.302 125.275 2.752 1.00 19.42 ? 319 PRO B CG 1 ATOM 5879 C CD . PRO C 1 267 ? -33.981 125.869 3.189 1.00 16.92 ? 319 PRO B CD 1 ATOM 5880 N N . TYR C 1 268 ? -35.319 122.485 6.034 1.00 21.19 ? 320 TYR B N 1 ATOM 5881 C CA . TYR C 1 268 ? -35.388 121.035 6.005 1.00 21.08 ? 320 TYR B CA 1 ATOM 5882 C C . TYR C 1 268 ? -36.793 120.573 6.370 1.00 21.91 ? 320 TYR B C 1 ATOM 5883 O O . TYR C 1 268 ? -37.382 121.059 7.334 1.00 25.24 ? 320 TYR B O 1 ATOM 5884 C CB . TYR C 1 268 ? -34.378 120.386 6.958 1.00 22.86 ? 320 TYR B CB 1 ATOM 5885 C CG . TYR C 1 268 ? -34.635 118.905 7.081 1.00 23.29 ? 320 TYR B CG 1 ATOM 5886 C CD1 . TYR C 1 268 ? -34.425 118.055 6.000 1.00 22.06 ? 320 TYR B CD1 1 ATOM 5887 C CD2 . TYR C 1 268 ? -35.134 118.359 8.255 1.00 22.95 ? 320 TYR B CD2 1 ATOM 5888 C CE1 . TYR C 1 268 ? -34.682 116.707 6.092 1.00 23.28 ? 320 TYR B CE1 1 ATOM 5889 C CE2 . TYR C 1 268 ? -35.390 117.011 8.359 1.00 25.20 ? 320 TYR B CE2 1 ATOM 5890 C CZ . TYR C 1 268 ? -35.162 116.187 7.274 1.00 23.83 ? 320 TYR B CZ 1 ATOM 5891 O OH . TYR C 1 268 ? -35.422 114.846 7.369 1.00 28.34 ? 320 TYR B OH 1 ATOM 5892 N N . LYS C 1 269 ? -37.310 119.646 5.577 1.00 21.65 ? 321 LYS B N 1 ATOM 5893 C CA . LYS C 1 269 ? -38.571 118.973 5.844 1.00 26.58 ? 321 LYS B CA 1 ATOM 5894 C C . LYS C 1 269 ? -38.391 117.503 5.479 1.00 30.28 ? 321 LYS B C 1 ATOM 5895 O O . LYS C 1 269 ? -37.709 117.187 4.502 1.00 27.15 ? 321 LYS B O 1 ATOM 5896 C CB . LYS C 1 269 ? -39.713 119.612 5.048 1.00 28.59 ? 321 LYS B CB 1 ATOM 5897 C CG . LYS C 1 269 ? -41.089 119.095 5.419 1.00 29.66 ? 321 LYS B CG 1 ATOM 5898 C CD . LYS C 1 269 ? -42.191 120.064 5.008 1.00 40.50 ? 321 LYS B CD 1 ATOM 5899 C CE . LYS C 1 269 ? -42.263 120.233 3.502 1.00 38.44 ? 321 LYS B CE 1 ATOM 5900 N NZ . LYS C 1 269 ? -43.431 121.074 3.105 1.00 39.24 ? 321 LYS B NZ 1 ATOM 5901 N N . SER C 1 270 ? -38.989 116.613 6.269 1.00 27.76 ? 322 SER B N 1 ATOM 5902 C CA . SER C 1 270 ? -38.793 115.170 6.118 1.00 29.83 ? 322 SER B CA 1 ATOM 5903 C C . SER C 1 270 ? -38.956 114.695 4.681 1.00 36.32 ? 322 SER B C 1 ATOM 5904 O O . SER C 1 270 ? -39.921 115.054 4.004 1.00 31.62 ? 322 SER B O 1 ATOM 5905 C CB . SER C 1 270 ? -39.771 114.408 7.016 1.00 40.09 ? 322 SER B CB 1 ATOM 5906 O OG . SER C 1 270 ? -39.542 114.700 8.383 1.00 44.96 ? 322 SER B OG 1 ATOM 5907 N N . GLY C 1 271 ? -38.002 113.887 4.226 1.00 32.00 ? 323 GLY B N 1 ATOM 5908 C CA . GLY C 1 271 ? -38.023 113.349 2.879 1.00 27.73 ? 323 GLY B CA 1 ATOM 5909 C C . GLY C 1 271 ? -37.175 114.162 1.918 1.00 31.96 ? 323 GLY B C 1 ATOM 5910 O O . GLY C 1 271 ? -36.841 113.692 0.830 1.00 36.43 ? 323 GLY B O 1 ATOM 5911 N N . GLY C 1 272 ? -36.833 115.384 2.319 1.00 29.05 ? 324 GLY B N 1 ATOM 5912 C CA . GLY C 1 272 ? -36.052 116.280 1.481 1.00 32.99 ? 324 GLY B CA 1 ATOM 5913 C C . GLY C 1 272 ? -34.590 116.315 1.883 1.00 25.88 ? 324 GLY B C 1 ATOM 5914 O O . GLY C 1 272 ? -34.192 115.663 2.851 1.00 22.83 ? 324 GLY B O 1 ATOM 5915 N N . ASN C 1 273 ? -33.787 117.067 1.131 1.00 22.37 ? 325 ASN B N 1 ATOM 5916 C CA . ASN C 1 273 ? -32.373 117.243 1.454 1.00 20.29 ? 325 ASN B CA 1 ATOM 5917 C C . ASN C 1 273 ? -32.163 118.036 2.729 1.00 21.42 ? 325 ASN B C 1 ATOM 5918 O O . ASN C 1 273 ? -32.838 119.034 2.987 1.00 23.86 ? 325 ASN B O 1 ATOM 5919 C CB . ASN C 1 273 ? -31.636 117.929 0.300 1.00 21.29 ? 325 ASN B CB 1 ATOM 5920 C CG . ASN C 1 273 ? -31.237 116.961 -0.788 1.00 25.70 ? 325 ASN B CG 1 ATOM 5921 O OD1 . ASN C 1 273 ? -31.982 116.742 -1.743 1.00 27.40 ? 325 ASN B OD1 1 ATOM 5922 N ND2 . ASN C 1 273 ? -30.056 116.367 -0.646 1.00 24.94 ? 325 ASN B ND2 1 ATOM 5923 N N . CYS C 1 274 ? -31.213 117.567 3.525 1.00 17.55 ? 326 CYS B N 1 ATOM 5924 C CA . CYS C 1 274 ? -30.830 118.211 4.764 1.00 17.63 ? 326 CYS B CA 1 ATOM 5925 C C . CYS C 1 274 ? -29.414 118.756 4.619 1.00 18.28 ? 326 CYS B C 1 ATOM 5926 O O . CYS C 1 274 ? -28.470 117.991 4.426 1.00 21.54 ? 326 CYS B O 1 ATOM 5927 C CB . CYS C 1 274 ? -30.921 117.209 5.915 1.00 19.20 ? 326 CYS B CB 1 ATOM 5928 S SG . CYS C 1 274 ? -31.058 117.959 7.548 1.00 22.32 ? 326 CYS B SG 1 ATOM 5929 N N . PHE C 1 275 ? -29.279 120.075 4.698 1.00 15.14 ? 327 PHE B N 1 ATOM 5930 C CA . PHE C 1 275 ? -28.013 120.757 4.463 1.00 14.70 ? 327 PHE B CA 1 ATOM 5931 C C . PHE C 1 275 ? -27.339 121.136 5.769 1.00 18.56 ? 327 PHE B C 1 ATOM 5932 O O . PHE C 1 275 ? -27.884 121.905 6.560 1.00 19.41 ? 327 PHE B O 1 ATOM 5933 C CB . PHE C 1 275 ? -28.232 122.006 3.598 1.00 15.16 ? 327 PHE B CB 1 ATOM 5934 C CG . PHE C 1 275 ? -28.797 121.699 2.241 1.00 15.36 ? 327 PHE B CG 1 ATOM 5935 C CD1 . PHE C 1 275 ? -27.963 121.326 1.195 1.00 14.90 ? 327 PHE B CD1 1 ATOM 5936 C CD2 . PHE C 1 275 ? -30.159 121.757 2.011 1.00 17.20 ? 327 PHE B CD2 1 ATOM 5937 C CE1 . PHE C 1 275 ? -28.483 121.022 -0.052 1.00 16.06 ? 327 PHE B CE1 1 ATOM 5938 C CE2 . PHE C 1 275 ? -30.682 121.455 0.770 1.00 16.73 ? 327 PHE B CE2 1 ATOM 5939 C CZ . PHE C 1 275 ? -29.840 121.088 -0.269 1.00 16.35 ? 327 PHE B CZ 1 ATOM 5940 N N . ARG C 1 276 ? -26.147 120.594 5.998 1.00 15.41 ? 328 ARG B N 1 ATOM 5941 C CA . ARG C 1 276 ? -25.407 120.874 7.222 1.00 15.79 ? 328 ARG B CA 1 ATOM 5942 C C . ARG C 1 276 ? -23.918 120.678 6.988 1.00 14.09 ? 328 ARG B C 1 ATOM 5943 O O . ARG C 1 276 ? -23.524 119.778 6.245 1.00 15.10 ? 328 ARG B O 1 ATOM 5944 C CB . ARG C 1 276 ? -25.880 119.972 8.369 1.00 17.70 ? 328 ARG B CB 1 ATOM 5945 C CG . ARG C 1 276 ? -25.160 120.246 9.673 1.00 16.56 ? 328 ARG B CG 1 ATOM 5946 C CD . ARG C 1 276 ? -25.748 119.461 10.834 1.00 18.42 ? 328 ARG B CD 1 ATOM 5947 N NE . ARG C 1 276 ? -24.985 119.697 12.056 1.00 19.08 ? 328 ARG B NE 1 ATOM 5948 C CZ . ARG C 1 276 ? -25.295 120.588 12.992 1.00 20.94 ? 328 ARG B CZ 1 ATOM 5949 N NH1 . ARG C 1 276 ? -26.380 121.345 12.880 1.00 18.93 ? 328 ARG B NH1 1 ATOM 5950 N NH2 . ARG C 1 276 ? -24.517 120.717 14.059 1.00 22.55 ? 328 ARG B NH2 1 ATOM 5951 N N . SER C 1 277 ? -23.107 121.529 7.607 1.00 14.31 ? 329 SER B N 1 ATOM 5952 C CA . SER C 1 277 ? -21.654 121.374 7.591 1.00 13.65 ? 329 SER B CA 1 ATOM 5953 C C . SER C 1 277 ? -21.140 121.326 6.156 1.00 16.25 ? 329 SER B C 1 ATOM 5954 O O . SER C 1 277 ? -20.318 120.491 5.803 1.00 12.65 ? 329 SER B O 1 ATOM 5955 C CB . SER C 1 277 ? -21.257 120.115 8.361 1.00 16.41 ? 329 SER B CB 1 ATOM 5956 O OG . SER C 1 277 ? -21.637 120.240 9.721 1.00 18.31 ? 329 SER B OG 1 ATOM 5957 N N . LEU C 1 278 ? -21.647 122.231 5.331 1.00 12.74 ? 330 LEU B N 1 ATOM 5958 C CA . LEU C 1 278 ? -21.322 122.224 3.910 1.00 13.13 ? 330 LEU B CA 1 ATOM 5959 C C . LEU C 1 278 ? -19.864 122.561 3.635 1.00 11.86 ? 330 LEU B C 1 ATOM 5960 O O . LEU C 1 278 ? -19.293 123.467 4.252 1.00 13.98 ? 330 LEU B O 1 ATOM 5961 C CB . LEU C 1 278 ? -22.211 123.214 3.163 1.00 13.37 ? 330 LEU B CB 1 ATOM 5962 C CG . LEU C 1 278 ? -23.704 122.905 3.225 1.00 12.78 ? 330 LEU B CG 1 ATOM 5963 C CD1 . LEU C 1 278 ? -24.448 123.989 2.439 1.00 15.45 ? 330 LEU B CD1 1 ATOM 5964 C CD2 . LEU C 1 278 ? -24.054 121.521 2.686 1.00 14.91 ? 330 LEU B CD2 1 ATOM 5965 N N . PRO C 1 279 ? -19.242 121.836 2.691 1.00 10.87 ? 331 PRO B N 1 ATOM 5966 C CA . PRO C 1 279 ? -17.898 122.239 2.289 1.00 11.55 ? 331 PRO B CA 1 ATOM 5967 C C . PRO C 1 279 ? -17.973 123.506 1.440 1.00 11.26 ? 331 PRO B C 1 ATOM 5968 O O . PRO C 1 279 ? -19.085 123.937 1.091 1.00 13.02 ? 331 PRO B O 1 ATOM 5969 C CB . PRO C 1 279 ? -17.392 121.026 1.501 1.00 13.12 ? 331 PRO B CB 1 ATOM 5970 C CG . PRO C 1 279 ? -18.603 120.427 0.921 1.00 11.97 ? 331 PRO B CG 1 ATOM 5971 C CD . PRO C 1 279 ? -19.718 120.670 1.922 1.00 12.85 ? 331 PRO B CD 1 ATOM 5972 N N . ALA C 1 280 ? -16.829 124.094 1.123 1.00 11.69 ? 332 ALA B N 1 ATOM 5973 C CA . ALA C 1 280 ? -16.803 125.357 0.409 1.00 11.76 ? 332 ALA B CA 1 ATOM 5974 C C . ALA C 1 280 ? -15.554 125.479 -0.443 1.00 16.05 ? 332 ALA B C 1 ATOM 5975 O O . ALA C 1 280 ? -14.559 124.786 -0.210 1.00 14.13 ? 332 ALA B O 1 ATOM 5976 C CB . ALA C 1 280 ? -16.881 126.522 1.403 1.00 13.08 ? 332 ALA B CB 1 ATOM 5977 N N . MET C 1 281 ? -15.620 126.370 -1.432 1.00 13.46 ? 333 MET B N 1 ATOM 5978 C CA . MET C 1 281 ? -14.483 126.730 -2.254 1.00 12.47 ? 333 MET B CA 1 ATOM 5979 C C . MET C 1 281 ? -14.036 128.141 -1.908 1.00 12.79 ? 333 MET B C 1 ATOM 5980 O O . MET C 1 281 ? -14.854 129.055 -1.880 1.00 15.53 ? 333 MET B O 1 ATOM 5981 C CB . MET C 1 281 ? -14.827 126.652 -3.742 1.00 14.94 ? 333 MET B CB 1 ATOM 5982 C CG . MET C 1 281 ? -15.189 125.255 -4.236 1.00 12.32 ? 333 MET B CG 1 ATOM 5983 S SD . MET C 1 281 ? -13.851 124.041 -4.037 1.00 13.04 ? 333 MET B SD 1 ATOM 5984 C CE . MET C 1 281 ? -12.525 124.831 -4.930 1.00 15.15 ? 333 MET B CE 1 ATOM 5985 N N . PHE C 1 282 ? -12.749 128.307 -1.628 1.00 13.13 ? 334 PHE B N 1 ATOM 5986 C CA . PHE C 1 282 ? -12.177 129.630 -1.423 1.00 15.66 ? 334 PHE B CA 1 ATOM 5987 C C . PHE C 1 282 ? -11.246 129.962 -2.576 1.00 14.99 ? 334 PHE B C 1 ATOM 5988 O O . PHE C 1 282 ? -10.478 129.121 -3.030 1.00 15.30 ? 334 PHE B O 1 ATOM 5989 C CB . PHE C 1 282 ? -11.425 129.718 -0.094 1.00 14.70 ? 334 PHE B CB 1 ATOM 5990 C CG . PHE C 1 282 ? -10.936 131.105 0.230 1.00 16.07 ? 334 PHE B CG 1 ATOM 5991 C CD1 . PHE C 1 282 ? -11.832 132.109 0.572 1.00 18.86 ? 334 PHE B CD1 1 ATOM 5992 C CD2 . PHE C 1 282 ? -9.589 131.404 0.200 1.00 14.96 ? 334 PHE B CD2 1 ATOM 5993 C CE1 . PHE C 1 282 ? -11.379 133.391 0.872 1.00 18.53 ? 334 PHE B CE1 1 ATOM 5994 C CE2 . PHE C 1 282 ? -9.134 132.681 0.507 1.00 19.32 ? 334 PHE B CE2 1 ATOM 5995 C CZ . PHE C 1 282 ? -10.037 133.668 0.836 1.00 19.66 ? 334 PHE B CZ 1 ATOM 5996 N N . ASP C 1 283 ? -11.331 131.198 -3.062 1.00 15.82 ? 335 ASP B N 1 ATOM 5997 C CA . ASP C 1 283 ? -10.463 131.672 -4.136 1.00 14.58 ? 335 ASP B CA 1 ATOM 5998 C C . ASP C 1 283 ? -9.438 132.631 -3.543 1.00 18.38 ? 335 ASP B C 1 ATOM 5999 O O . ASP C 1 283 ? -9.793 133.724 -3.102 1.00 18.98 ? 335 ASP B O 1 ATOM 6000 C CB . ASP C 1 283 ? -11.298 132.348 -5.233 1.00 17.99 ? 335 ASP B CB 1 ATOM 6001 C CG . ASP C 1 283 ? -10.495 132.668 -6.487 1.00 20.42 ? 335 ASP B CG 1 ATOM 6002 O OD1 . ASP C 1 283 ? -9.296 132.987 -6.377 1.00 21.26 ? 335 ASP B OD1 1 ATOM 6003 O OD2 . ASP C 1 283 ? -11.084 132.630 -7.591 1.00 23.96 ? 335 ASP B OD2 1 ATOM 6004 N N . MET C 1 284 ? -8.177 132.207 -3.520 1.00 18.40 ? 336 MET B N 1 ATOM 6005 C CA . MET C 1 284 ? -7.102 132.976 -2.891 1.00 19.01 ? 336 MET B CA 1 ATOM 6006 C C . MET C 1 284 ? -6.862 134.314 -3.571 1.00 22.63 ? 336 MET B C 1 ATOM 6007 O O . MET C 1 284 ? -6.326 135.236 -2.955 1.00 27.13 ? 336 MET B O 1 ATOM 6008 C CB . MET C 1 284 ? -5.795 132.186 -2.907 1.00 25.80 ? 336 MET B CB 1 ATOM 6009 C CG . MET C 1 284 ? -5.822 130.883 -2.142 1.00 23.10 ? 336 MET B CG 1 ATOM 6010 S SD . MET C 1 284 ? -5.810 131.070 -0.352 1.00 25.32 ? 336 MET B SD 1 ATOM 6011 C CE . MET C 1 284 ? -4.196 131.818 -0.119 1.00 29.13 ? 336 MET B CE 1 ATOM 6012 N N . SER C 1 285 ? -7.237 134.420 -4.840 1.00 21.05 ? 337 SER B N 1 ATOM 6013 C CA . SER C 1 285 ? -6.905 135.610 -5.614 1.00 23.33 ? 337 SER B CA 1 ATOM 6014 C C . SER C 1 285 ? -8.030 136.648 -5.592 1.00 27.26 ? 337 SER B C 1 ATOM 6015 O O . SER C 1 285 ? -7.765 137.836 -5.758 1.00 29.13 ? 337 SER B O 1 ATOM 6016 C CB . SER C 1 285 ? -6.557 135.227 -7.054 1.00 26.56 ? 337 SER B CB 1 ATOM 6017 O OG . SER C 1 285 ? -7.666 134.674 -7.730 1.00 36.02 ? 337 SER B OG 1 ATOM 6018 N N . THR C 1 286 ? -9.270 136.216 -5.365 1.00 22.31 ? 338 THR B N 1 ATOM 6019 C CA . THR C 1 286 ? -10.409 137.142 -5.339 1.00 21.69 ? 338 THR B CA 1 ATOM 6020 C C . THR C 1 286 ? -11.056 137.267 -3.963 1.00 21.30 ? 338 THR B C 1 ATOM 6021 O O . THR C 1 286 ? -11.809 138.206 -3.708 1.00 24.55 ? 338 THR B O 1 ATOM 6022 C CB . THR C 1 286 ? -11.497 136.713 -6.326 1.00 21.64 ? 338 THR B CB 1 ATOM 6023 O OG1 . THR C 1 286 ? -12.140 135.519 -5.846 1.00 21.01 ? 338 THR B OG1 1 ATOM 6024 C CG2 . THR C 1 286 ? -10.906 136.478 -7.713 1.00 26.41 ? 338 THR B CG2 1 ATOM 6025 N N . GLY C 1 287 ? -10.779 136.312 -3.082 1.00 19.03 ? 339 GLY B N 1 ATOM 6026 C CA . GLY C 1 287 ? -11.389 136.287 -1.766 1.00 16.84 ? 339 GLY B CA 1 ATOM 6027 C C . GLY C 1 287 ? -12.790 135.705 -1.744 1.00 16.65 ? 339 GLY B C 1 ATOM 6028 O O . GLY C 1 287 ? -13.447 135.694 -0.705 1.00 18.79 ? 339 GLY B O 1 ATOM 6029 N N . GLU C 1 288 ? -13.258 135.203 -2.883 1.00 16.87 ? 340 GLU B N 1 ATOM 6030 C CA . GLU C 1 288 ? -14.601 134.651 -2.936 1.00 15.10 ? 340 GLU B CA 1 ATOM 6031 C C . GLU C 1 288 ? -14.706 133.346 -2.131 1.00 16.21 ? 340 GLU B C 1 ATOM 6032 O O . GLU C 1 288 ? -13.892 132.440 -2.308 1.00 17.19 ? 340 GLU B O 1 ATOM 6033 C CB . GLU C 1 288 ? -15.029 134.406 -4.382 1.00 18.59 ? 340 GLU B CB 1 ATOM 6034 C CG . GLU C 1 288 ? -16.441 133.851 -4.455 1.00 15.24 ? 340 GLU B CG 1 ATOM 6035 C CD . GLU C 1 288 ? -17.042 133.881 -5.849 1.00 21.71 ? 340 GLU B CD 1 ATOM 6036 O OE1 . GLU C 1 288 ? -16.281 133.975 -6.838 1.00 31.38 ? 340 GLU B OE1 1 ATOM 6037 O OE2 . GLU C 1 288 ? -18.284 133.816 -5.946 1.00 17.65 ? 340 GLU B OE2 1 ATOM 6038 N N . CYS C 1 289 ? -15.711 133.273 -1.260 1.00 14.65 ? 341 CYS B N 1 ATOM 6039 C CA . CYS C 1 289 ? -16.048 132.068 -0.501 1.00 15.47 ? 341 CYS B CA 1 ATOM 6040 C C . CYS C 1 289 ? -17.406 131.580 -0.974 1.00 17.63 ? 341 CYS B C 1 ATOM 6041 O O . CYS C 1 289 ? -18.412 132.272 -0.813 1.00 17.21 ? 341 CYS B O 1 ATOM 6042 C CB . CYS C 1 289 ? -16.076 132.346 1.007 1.00 16.85 ? 341 CYS B CB 1 ATOM 6043 S SG . CYS C 1 289 ? -16.568 130.956 2.036 1.00 20.99 ? 341 CYS B SG 1 ATOM 6044 N N . ARG C 1 290 ? -17.434 130.381 -1.549 1.00 14.42 ? 342 ARG B N 1 ATOM 6045 C CA . ARG C 1 290 ? -18.640 129.825 -2.136 1.00 12.71 ? 342 ARG B CA 1 ATOM 6046 C C . ARG C 1 290 ? -18.954 128.500 -1.462 1.00 13.84 ? 342 ARG B C 1 ATOM 6047 O O . ARG C 1 290 ? -18.138 127.570 -1.488 1.00 14.94 ? 342 ARG B O 1 ATOM 6048 C CB . ARG C 1 290 ? -18.478 129.618 -3.644 1.00 12.63 ? 342 ARG B CB 1 ATOM 6049 C CG . ARG C 1 290 ? -19.781 129.400 -4.386 1.00 14.03 ? 342 ARG B CG 1 ATOM 6050 C CD . ARG C 1 290 ? -20.426 130.745 -4.764 1.00 13.14 ? 342 ARG B CD 1 ATOM 6051 N NE . ARG C 1 290 ? -21.730 130.571 -5.391 1.00 13.47 ? 342 ARG B NE 1 ATOM 6052 C CZ . ARG C 1 290 ? -21.913 130.089 -6.617 1.00 12.61 ? 342 ARG B CZ 1 ATOM 6053 N NH1 . ARG C 1 290 ? -20.868 129.738 -7.356 1.00 12.84 ? 342 ARG B NH1 1 ATOM 6054 N NH2 . ARG C 1 290 ? -23.137 129.965 -7.106 1.00 14.24 ? 342 ARG B NH2 1 ATOM 6055 N N . LEU C 1 291 ? -20.131 128.410 -0.861 1.00 11.41 ? 343 LEU B N 1 ATOM 6056 C CA . LEU C 1 291 ? -20.586 127.175 -0.253 1.00 12.48 ? 343 LEU B CA 1 ATOM 6057 C C . LEU C 1 291 ? -20.978 126.185 -1.332 1.00 11.53 ? 343 LEU B C 1 ATOM 6058 O O . LEU C 1 291 ? -21.593 126.554 -2.335 1.00 12.06 ? 343 LEU B O 1 ATOM 6059 C CB . LEU C 1 291 ? -21.782 127.421 0.673 1.00 13.26 ? 343 LEU B CB 1 ATOM 6060 C CG . LEU C 1 291 ? -21.543 128.395 1.828 1.00 13.34 ? 343 LEU B CG 1 ATOM 6061 C CD1 . LEU C 1 291 ? -22.858 128.661 2.541 1.00 17.04 ? 343 LEU B CD1 1 ATOM 6062 C CD2 . LEU C 1 291 ? -20.487 127.880 2.799 1.00 18.29 ? 343 LEU B CD2 1 ATOM 6063 N N . LEU C 1 292 ? -20.619 124.921 -1.121 1.00 12.92 ? 344 LEU B N 1 ATOM 6064 C CA . LEU C 1 292 ? -21.066 123.841 -1.984 1.00 12.64 ? 344 LEU B CA 1 ATOM 6065 C C . LEU C 1 292 ? -22.278 123.156 -1.380 1.00 11.17 ? 344 LEU B C 1 ATOM 6066 O O . LEU C 1 292 ? -22.384 123.015 -0.154 1.00 14.06 ? 344 LEU B O 1 ATOM 6067 C CB . LEU C 1 292 ? -19.957 122.820 -2.187 1.00 11.71 ? 344 LEU B CB 1 ATOM 6068 C CG . LEU C 1 292 ? -18.650 123.362 -2.750 1.00 11.85 ? 344 LEU B CG 1 ATOM 6069 C CD1 . LEU C 1 292 ? -17.605 122.256 -2.807 1.00 15.70 ? 344 LEU B CD1 1 ATOM 6070 C CD2 . LEU C 1 292 ? -18.854 123.994 -4.127 1.00 14.42 ? 344 LEU B CD2 1 ATOM 6071 N N . GLY C 1 293 ? -23.191 122.703 -2.227 1.00 11.77 ? 345 GLY B N 1 ATOM 6072 C CA . GLY C 1 293 ? -24.429 122.122 -1.749 1.00 11.45 ? 345 GLY B CA 1 ATOM 6073 C C . GLY C 1 293 ? -24.359 120.632 -1.458 1.00 11.73 ? 345 GLY B C 1 ATOM 6074 O O . GLY C 1 293 ? -25.261 120.064 -0.845 1.00 12.23 ? 345 GLY B O 1 ATOM 6075 N N . TYR C 1 294 ? -23.286 120.002 -1.921 1.00 12.00 ? 346 TYR B N 1 ATOM 6076 C CA . TYR C 1 294 ? -23.118 118.564 -1.845 1.00 12.45 ? 346 TYR B CA 1 ATOM 6077 C C . TYR C 1 294 ? -21.806 118.208 -1.155 1.00 10.43 ? 346 TYR B C 1 ATOM 6078 O O . TYR C 1 294 ? -20.787 118.864 -1.371 1.00 11.50 ? 346 TYR B O 1 ATOM 6079 C CB . TYR C 1 294 ? -23.125 117.961 -3.245 1.00 11.50 ? 346 TYR B CB 1 ATOM 6080 C CG . TYR C 1 294 ? -24.422 118.050 -4.021 1.00 12.50 ? 346 TYR B CG 1 ATOM 6081 C CD1 . TYR C 1 294 ? -25.643 117.774 -3.423 1.00 13.65 ? 346 TYR B CD1 1 ATOM 6082 C CD2 . TYR C 1 294 ? -24.411 118.355 -5.377 1.00 13.10 ? 346 TYR B CD2 1 ATOM 6083 C CE1 . TYR C 1 294 ? -26.824 117.821 -4.154 1.00 13.80 ? 346 TYR B CE1 1 ATOM 6084 C CE2 . TYR C 1 294 ? -25.585 118.404 -6.117 1.00 13.36 ? 346 TYR B CE2 1 ATOM 6085 C CZ . TYR C 1 294 ? -26.787 118.132 -5.498 1.00 14.21 ? 346 TYR B CZ 1 ATOM 6086 O OH . TYR C 1 294 ? -27.970 118.177 -6.216 1.00 15.85 ? 346 TYR B OH 1 ATOM 6087 N N . HIS C 1 295 ? -21.846 117.156 -0.341 1.00 10.47 ? 347 HIS B N 1 ATOM 6088 C CA . HIS C 1 295 ? -20.651 116.614 0.311 1.00 10.32 ? 347 HIS B CA 1 ATOM 6089 C C . HIS C 1 295 ? -19.835 115.675 -0.583 1.00 11.13 ? 347 HIS B C 1 ATOM 6090 O O . HIS C 1 295 ? -18.630 115.510 -0.373 1.00 10.47 ? 347 HIS B O 1 ATOM 6091 C CB . HIS C 1 295 ? -21.043 115.861 1.577 1.00 11.82 ? 347 HIS B CB 1 ATOM 6092 C CG . HIS C 1 295 ? -21.680 116.725 2.618 1.00 12.10 ? 347 HIS B CG 1 ATOM 6093 N ND1 . HIS C 1 295 ? -20.957 117.598 3.402 1.00 12.05 ? 347 HIS B ND1 1 ATOM 6094 C CD2 . HIS C 1 295 ? -22.974 116.868 2.986 1.00 13.92 ? 347 HIS B CD2 1 ATOM 6095 C CE1 . HIS C 1 295 ? -21.778 118.225 4.226 1.00 13.19 ? 347 HIS B CE1 1 ATOM 6096 N NE2 . HIS C 1 295 ? -23.008 117.806 3.988 1.00 12.21 ? 347 HIS B NE2 1 ATOM 6097 N N . THR C 1 296 ? -20.507 115.037 -1.538 1.00 10.99 ? 348 THR B N 1 ATOM 6098 C CA . THR C 1 296 ? -19.861 114.118 -2.471 1.00 8.27 ? 348 THR B CA 1 ATOM 6099 C C . THR C 1 296 ? -18.651 114.772 -3.116 1.00 11.64 ? 348 THR B C 1 ATOM 6100 O O . THR C 1 296 ? -18.733 115.922 -3.550 1.00 10.80 ? 348 THR B O 1 ATOM 6101 C CB . THR C 1 296 ? -20.853 113.673 -3.570 1.00 10.86 ? 348 THR B CB 1 ATOM 6102 O OG1 . THR C 1 296 ? -21.950 112.976 -2.973 1.00 11.00 ? 348 THR B OG1 1 ATOM 6103 C CG2 . THR C 1 296 ? -20.181 112.759 -4.581 1.00 10.80 ? 348 THR B CG2 1 ATOM 6104 N N . GLN C 1 297 ? -17.533 114.047 -3.175 1.00 8.99 ? 349 GLN B N 1 ATOM 6105 C CA . GLN C 1 297 ? -16.358 114.531 -3.884 1.00 9.87 ? 349 GLN B CA 1 ATOM 6106 C C . GLN C 1 297 ? -15.986 113.680 -5.100 1.00 10.37 ? 349 GLN B C 1 ATOM 6107 O O . GLN C 1 297 ? -15.256 114.151 -5.969 1.00 12.03 ? 349 GLN B O 1 ATOM 6108 C CB . GLN C 1 297 ? -15.170 114.629 -2.932 1.00 9.61 ? 349 GLN B CB 1 ATOM 6109 C CG . GLN C 1 297 ? -15.312 115.731 -1.902 1.00 10.64 ? 349 GLN B CG 1 ATOM 6110 C CD . GLN C 1 297 ? -14.746 115.333 -0.564 1.00 9.58 ? 349 GLN B CD 1 ATOM 6111 O OE1 . GLN C 1 297 ? -13.533 115.262 -0.386 1.00 10.46 ? 349 GLN B OE1 1 ATOM 6112 N NE2 . GLN C 1 297 ? -15.627 115.067 0.391 1.00 11.43 ? 349 GLN B NE2 1 ATOM 6113 N N . ASP C 1 298 ? -16.489 112.445 -5.164 1.00 10.01 ? 350 ASP B N 1 ATOM 6114 C CA . ASP C 1 298 ? -16.230 111.559 -6.292 1.00 10.64 ? 350 ASP B CA 1 ATOM 6115 C C . ASP C 1 298 ? -17.455 110.696 -6.534 1.00 10.21 ? 350 ASP B C 1 ATOM 6116 O O . ASP C 1 298 ? -17.991 110.097 -5.603 1.00 11.45 ? 350 ASP B O 1 ATOM 6117 C CB . ASP C 1 298 ? -14.997 110.691 -6.016 1.00 10.85 ? 350 ASP B CB 1 ATOM 6118 C CG . ASP C 1 298 ? -14.465 109.992 -7.258 1.00 14.23 ? 350 ASP B CG 1 ATOM 6119 O OD1 . ASP C 1 298 ? -15.082 109.009 -7.697 1.00 15.83 ? 350 ASP B OD1 1 ATOM 6120 O OD2 . ASP C 1 298 ? -13.406 110.398 -7.773 1.00 15.95 ? 350 ASP B OD2 1 ATOM 6121 N N . PHE C 1 299 ? -17.908 110.643 -7.779 1.00 10.58 ? 351 PHE B N 1 ATOM 6122 C CA . PHE C 1 299 ? -18.983 109.738 -8.167 1.00 8.14 ? 351 PHE B CA 1 ATOM 6123 C C . PHE C 1 299 ? -18.723 109.312 -9.598 1.00 11.91 ? 351 PHE B C 1 ATOM 6124 O O . PHE C 1 299 ? -18.584 110.154 -10.476 1.00 10.26 ? 351 PHE B O 1 ATOM 6125 C CB . PHE C 1 299 ? -20.354 110.412 -8.019 1.00 8.86 ? 351 PHE B CB 1 ATOM 6126 C CG . PHE C 1 299 ? -21.518 109.479 -8.206 1.00 10.33 ? 351 PHE B CG 1 ATOM 6127 C CD1 . PHE C 1 299 ? -21.640 108.347 -7.422 1.00 10.94 ? 351 PHE B CD1 1 ATOM 6128 C CD2 . PHE C 1 299 ? -22.504 109.749 -9.139 1.00 9.99 ? 351 PHE B CD2 1 ATOM 6129 C CE1 . PHE C 1 299 ? -22.715 107.482 -7.576 1.00 13.00 ? 351 PHE B CE1 1 ATOM 6130 C CE2 . PHE C 1 299 ? -23.586 108.880 -9.299 1.00 11.22 ? 351 PHE B CE2 1 ATOM 6131 C CZ . PHE C 1 299 ? -23.688 107.751 -8.514 1.00 12.62 ? 351 PHE B CZ 1 ATOM 6132 N N . ARG C 1 300 ? -18.622 108.005 -9.827 1.00 10.81 ? 352 ARG B N 1 ATOM 6133 C CA . ARG C 1 300 ? -18.236 107.483 -11.138 1.00 9.01 ? 352 ARG B CA 1 ATOM 6134 C C . ARG C 1 300 ? -18.903 106.128 -11.422 1.00 11.79 ? 352 ARG B C 1 ATOM 6135 O O . ARG C 1 300 ? -18.449 105.383 -12.290 1.00 13.38 ? 352 ARG B O 1 ATOM 6136 C CB . ARG C 1 300 ? -16.710 107.357 -11.236 1.00 12.93 ? 352 ARG B CB 1 ATOM 6137 C CG . ARG C 1 300 ? -16.109 106.375 -10.240 1.00 12.02 ? 352 ARG B CG 1 ATOM 6138 C CD . ARG C 1 300 ? -14.609 106.252 -10.403 1.00 12.56 ? 352 ARG B CD 1 ATOM 6139 N NE . ARG C 1 300 ? -13.898 107.436 -9.927 1.00 12.85 ? 352 ARG B NE 1 ATOM 6140 C CZ . ARG C 1 300 ? -12.617 107.672 -10.168 1.00 11.05 ? 352 ARG B CZ 1 ATOM 6141 N NH1 . ARG C 1 300 ? -11.906 106.809 -10.882 1.00 11.97 ? 352 ARG B NH1 1 ATOM 6142 N NH2 . ARG C 1 300 ? -12.040 108.763 -9.690 1.00 12.91 ? 352 ARG B NH2 1 ATOM 6143 N N . SER C 1 301 ? -19.977 105.834 -10.696 1.00 12.45 ? 353 SER B N 1 ATOM 6144 C CA . SER C 1 301 ? -20.775 104.622 -10.895 1.00 14.83 ? 353 SER B CA 1 ATOM 6145 C C . SER C 1 301 ? -21.396 104.561 -12.276 1.00 14.86 ? 353 SER B C 1 ATOM 6146 O O . SER C 1 301 ? -21.499 105.566 -12.957 1.00 14.88 ? 353 SER B O 1 ATOM 6147 C CB . SER C 1 301 ? -21.900 104.551 -9.868 1.00 16.33 ? 353 SER B CB 1 ATOM 6148 O OG . SER C 1 301 ? -21.400 104.613 -8.548 1.00 22.87 ? 353 SER B OG 1 ATOM 6149 N N . SER C 1 302 ? -21.879 103.384 -12.655 1.00 14.12 ? 354 SER B N 1 ATOM 6150 C CA . SER C 1 302 ? -22.515 103.211 -13.949 1.00 15.20 ? 354 SER B CA 1 ATOM 6151 C C . SER C 1 302 ? -23.754 104.077 -14.136 1.00 16.10 ? 354 SER B C 1 ATOM 6152 O O . SER C 1 302 ? -24.169 104.324 -15.265 1.00 19.47 ? 354 SER B O 1 ATOM 6153 C CB . SER C 1 302 ? -22.903 101.750 -14.146 1.00 15.36 ? 354 SER B CB 1 ATOM 6154 O OG . SER C 1 302 ? -23.762 101.332 -13.099 1.00 17.86 ? 354 SER B OG 1 ATOM 6155 N N . THR C 1 303 ? -24.335 104.529 -13.029 1.00 14.67 ? 355 THR B N 1 ATOM 6156 C CA . THR C 1 303 ? -25.542 105.345 -13.060 1.00 16.82 ? 355 THR B CA 1 ATOM 6157 C C . THR C 1 303 ? -25.242 106.839 -13.053 1.00 17.45 ? 355 THR B C 1 ATOM 6158 O O . THR C 1 303 ? -26.167 107.652 -13.101 1.00 17.62 ? 355 THR B O 1 ATOM 6159 C CB . THR C 1 303 ? -26.447 105.041 -11.859 1.00 17.64 ? 355 THR B CB 1 ATOM 6160 O OG1 . THR C 1 303 ? -25.716 105.271 -10.648 1.00 22.10 ? 355 THR B OG1 1 ATOM 6161 C CG2 . THR C 1 303 ? -26.931 103.603 -11.906 1.00 20.44 ? 355 THR B CG2 1 ATOM 6162 N N . CYS C 1 304 ? -23.972 107.218 -12.982 1.00 14.47 ? 356 CYS B N 1 ATOM 6163 C CA . CYS C 1 304 ? -23.655 108.643 -12.930 1.00 13.27 ? 356 CYS B CA 1 ATOM 6164 C C . CYS C 1 304 ? -23.948 109.269 -14.288 1.00 18.57 ? 356 CYS B C 1 ATOM 6165 O O . CYS C 1 304 ? -23.801 108.622 -15.331 1.00 15.74 ? 356 CYS B O 1 ATOM 6166 C CB . CYS C 1 304 ? -22.199 108.880 -12.496 1.00 13.57 ? 356 CYS B CB 1 ATOM 6167 S SG . CYS C 1 304 ? -20.856 108.513 -13.675 1.00 18.69 ? 356 CYS B SG 1 ATOM 6168 N N . ALA C 1 305 ? -24.407 110.519 -14.266 1.00 15.70 ? 357 ALA B N 1 ATOM 6169 C CA . ALA C 1 305 ? -24.700 111.250 -15.489 1.00 15.35 ? 357 ALA B CA 1 ATOM 6170 C C . ALA C 1 305 ? -23.442 111.907 -16.034 1.00 12.86 ? 357 ALA B C 1 ATOM 6171 O O . ALA C 1 305 ? -22.756 112.657 -15.332 1.00 14.24 ? 357 ALA B O 1 ATOM 6172 C CB . ALA C 1 305 ? -25.782 112.291 -15.238 1.00 17.16 ? 357 ALA B CB 1 ATOM 6173 N N . GLU C 1 306 ? -23.130 111.612 -17.291 1.00 15.47 ? 358 GLU B N 1 ATOM 6174 C CA . GLU C 1 306 ? -21.939 112.166 -17.928 1.00 14.17 ? 358 GLU B CA 1 ATOM 6175 C C . GLU C 1 306 ? -22.232 113.536 -18.545 1.00 15.20 ? 358 GLU B C 1 ATOM 6176 O O . GLU C 1 306 ? -22.765 113.639 -19.661 1.00 16.89 ? 358 GLU B O 1 ATOM 6177 C CB . GLU C 1 306 ? -21.396 111.196 -18.985 1.00 16.31 ? 358 GLU B CB 1 ATOM 6178 C CG . GLU C 1 306 ? -21.029 109.820 -18.422 1.00 19.00 ? 358 GLU B CG 1 ATOM 6179 C CD . GLU C 1 306 ? -20.380 108.908 -19.454 1.00 15.57 ? 358 GLU B CD 1 ATOM 6180 O OE1 . GLU C 1 306 ? -19.139 108.925 -19.570 1.00 15.59 ? 358 GLU B OE1 1 ATOM 6181 O OE2 . GLU C 1 306 ? -21.109 108.159 -20.146 1.00 22.45 ? 358 GLU B OE2 1 ATOM 6182 N N . LEU C 1 307 ? -21.897 114.573 -17.774 1.00 16.55 ? 359 LEU B N 1 ATOM 6183 C CA . LEU C 1 307 ? -21.902 115.988 -18.188 1.00 15.49 ? 359 LEU B CA 1 ATOM 6184 C C . LEU C 1 307 ? -23.288 116.602 -18.388 1.00 15.73 ? 359 LEU B C 1 ATOM 6185 O O . LEU C 1 307 ? -23.493 117.758 -18.025 1.00 17.35 ? 359 LEU B O 1 ATOM 6186 C CB . LEU C 1 307 ? -21.074 116.176 -19.466 1.00 16.53 ? 359 LEU B CB 1 ATOM 6187 C CG . LEU C 1 307 ? -19.588 115.826 -19.332 1.00 15.19 ? 359 LEU B CG 1 ATOM 6188 C CD1 . LEU C 1 307 ? -18.852 115.959 -20.670 1.00 16.95 ? 359 LEU B CD1 1 ATOM 6189 C CD2 . LEU C 1 307 ? -18.890 116.685 -18.276 1.00 18.52 ? 359 LEU B CD2 1 ATOM 6190 N N . THR C 1 308 ? -24.226 115.853 -18.952 1.00 17.47 ? 360 THR B N 1 ATOM 6191 C CA . THR C 1 308 ? -25.590 116.348 -19.102 1.00 17.35 ? 360 THR B CA 1 ATOM 6192 C C . THR C 1 308 ? -26.635 115.269 -18.889 1.00 16.93 ? 360 THR B C 1 ATOM 6193 O O . THR C 1 308 ? -26.518 114.140 -19.378 1.00 19.84 ? 360 THR B O 1 ATOM 6194 C CB . THR C 1 308 ? -25.830 116.959 -20.498 1.00 22.42 ? 360 THR B CB 1 ATOM 6195 O OG1 . THR C 1 308 ? -25.609 115.961 -21.497 1.00 30.83 ? 360 THR B OG1 1 ATOM 6196 C CG2 . THR C 1 308 ? -24.903 118.131 -20.751 1.00 25.89 ? 360 THR B CG2 1 ATOM 6197 N N . THR C 1 309 ? -27.675 115.635 -18.156 1.00 15.32 ? 361 THR B N 1 ATOM 6198 C CA . THR C 1 309 ? -28.860 114.810 -18.034 1.00 16.88 ? 361 THR B CA 1 ATOM 6199 C C . THR C 1 309 ? -30.060 115.685 -17.686 1.00 16.46 ? 361 THR B C 1 ATOM 6200 O O . THR C 1 309 ? -29.898 116.800 -17.167 1.00 16.14 ? 361 THR B O 1 ATOM 6201 C CB . THR C 1 309 ? -28.712 113.718 -16.954 1.00 16.54 ? 361 THR B CB 1 ATOM 6202 O OG1 . THR C 1 309 ? -29.853 112.849 -17.002 1.00 19.61 ? 361 THR B OG1 1 ATOM 6203 C CG2 . THR C 1 309 ? -28.582 114.332 -15.550 1.00 16.42 ? 361 THR B CG2 1 ATOM 6204 N N . ASP C 1 310 ? -31.247 115.159 -17.979 1.00 18.79 ? 362 ASP B N 1 ATOM 6205 C CA . ASP C 1 310 ? -32.523 115.763 -17.593 1.00 19.59 ? 362 ASP B CA 1 ATOM 6206 C C . ASP C 1 310 ? -33.124 115.106 -16.359 1.00 21.23 ? 362 ASP B C 1 ATOM 6207 O O . ASP C 1 310 ? -34.109 115.590 -15.810 1.00 20.56 ? 362 ASP B O 1 ATOM 6208 C CB . ASP C 1 310 ? -33.545 115.650 -18.727 1.00 23.31 ? 362 ASP B CB 1 ATOM 6209 C CG . ASP C 1 310 ? -33.186 116.477 -19.932 1.00 40.31 ? 362 ASP B CG 1 ATOM 6210 O OD1 . ASP C 1 310 ? -32.522 117.524 -19.775 1.00 36.99 ? 362 ASP B OD1 1 ATOM 6211 O OD2 . ASP C 1 310 ? -33.586 116.080 -21.047 1.00 49.96 ? 362 ASP B OD2 1 ATOM 6212 N N . ASP C 1 311 ? -32.547 113.983 -15.945 1.00 18.66 ? 363 ASP B N 1 ATOM 6213 C CA . ASP C 1 311 ? -33.092 113.185 -14.849 1.00 17.98 ? 363 ASP B CA 1 ATOM 6214 C C . ASP C 1 311 ? -32.728 113.797 -13.495 1.00 18.33 ? 363 ASP B C 1 ATOM 6215 O O . ASP C 1 311 ? -31.582 113.715 -13.059 1.00 17.16 ? 363 ASP B O 1 ATOM 6216 C CB . ASP C 1 311 ? -32.574 111.747 -14.968 1.00 18.40 ? 363 ASP B CB 1 ATOM 6217 C CG . ASP C 1 311 ? -33.083 110.827 -13.866 1.00 20.21 ? 363 ASP B CG 1 ATOM 6218 O OD1 . ASP C 1 311 ? -33.894 111.255 -13.020 1.00 20.88 ? 363 ASP B OD1 1 ATOM 6219 O OD2 . ASP C 1 311 ? -32.663 109.648 -13.856 1.00 24.47 ? 363 ASP B OD2 1 ATOM 6220 N N . THR C 1 312 ? -33.705 114.410 -12.831 1.00 19.74 ? 364 THR B N 1 ATOM 6221 C CA . THR C 1 312 ? -33.445 115.118 -11.581 1.00 18.55 ? 364 THR B CA 1 ATOM 6222 C C . THR C 1 312 ? -33.205 114.183 -10.397 1.00 21.09 ? 364 THR B C 1 ATOM 6223 O O . THR C 1 312 ? -32.927 114.649 -9.291 1.00 24.56 ? 364 THR B O 1 ATOM 6224 C CB . THR C 1 312 ? -34.601 116.068 -11.233 1.00 22.30 ? 364 THR B CB 1 ATOM 6225 O OG1 . THR C 1 312 ? -35.825 115.330 -11.119 1.00 23.55 ? 364 THR B OG1 1 ATOM 6226 C CG2 . THR C 1 312 ? -34.748 117.119 -12.312 1.00 23.28 ? 364 THR B CG2 1 ATOM 6227 N N . ASN C 1 313 ? -33.316 112.878 -10.630 1.00 20.59 ? 365 ASN B N 1 ATOM 6228 C CA A ASN C 1 313 ? -33.021 111.856 -9.630 0.47 21.51 ? 365 ASN B CA 1 ATOM 6229 C CA B ASN C 1 313 ? -32.989 111.912 -9.589 0.53 21.49 ? 365 ASN B CA 1 ATOM 6230 C C . ASN C 1 313 ? -31.590 111.332 -9.781 1.00 22.43 ? 365 ASN B C 1 ATOM 6231 O O . ASN C 1 313 ? -31.111 110.566 -8.947 1.00 23.50 ? 365 ASN B O 1 ATOM 6232 C CB A ASN C 1 313 ? -34.028 110.701 -9.748 0.47 24.02 ? 365 ASN B CB 1 ATOM 6233 C CB B ASN C 1 313 ? -34.035 110.801 -9.550 0.53 23.96 ? 365 ASN B CB 1 ATOM 6234 C CG A ASN C 1 313 ? -33.747 109.564 -8.777 0.47 28.34 ? 365 ASN B CG 1 ATOM 6235 C CG B ASN C 1 313 ? -35.380 111.295 -9.049 0.53 26.81 ? 365 ASN B CG 1 ATOM 6236 O OD1 A ASN C 1 313 ? -33.851 109.729 -7.563 0.47 27.40 ? 365 ASN B OD1 1 ATOM 6237 O OD1 B ASN C 1 313 ? -35.448 112.127 -8.143 0.53 31.34 ? 365 ASN B OD1 1 ATOM 6238 N ND2 A ASN C 1 313 ? -33.410 108.396 -9.315 0.47 31.08 ? 365 ASN B ND2 1 ATOM 6239 N ND2 B ASN C 1 313 ? -36.455 110.798 -9.646 0.53 30.68 ? 365 ASN B ND2 1 ATOM 6240 N N . ALA C 1 314 ? -30.915 111.741 -10.857 1.00 19.70 ? 366 ALA B N 1 ATOM 6241 C CA . ALA C 1 314 ? -29.553 111.280 -11.129 1.00 17.66 ? 366 ALA B CA 1 ATOM 6242 C C . ALA C 1 314 ? -28.527 112.195 -10.474 1.00 14.28 ? 366 ALA B C 1 ATOM 6243 O O . ALA C 1 314 ? -28.837 113.328 -10.116 1.00 16.25 ? 366 ALA B O 1 ATOM 6244 C CB . ALA C 1 314 ? -29.294 111.201 -12.633 1.00 17.65 ? 366 ALA B CB 1 ATOM 6245 N N . PHE C 1 315 ? -27.312 111.677 -10.307 1.00 13.04 ? 367 PHE B N 1 ATOM 6246 C CA . PHE C 1 315 ? -26.189 112.465 -9.808 1.00 11.49 ? 367 PHE B CA 1 ATOM 6247 C C . PHE C 1 315 ? -25.072 112.437 -10.844 1.00 11.83 ? 367 PHE B C 1 ATOM 6248 O O . PHE C 1 315 ? -24.829 111.416 -11.483 1.00 12.54 ? 367 PHE B O 1 ATOM 6249 C CB . PHE C 1 315 ? -25.695 111.938 -8.451 1.00 12.62 ? 367 PHE B CB 1 ATOM 6250 C CG . PHE C 1 315 ? -24.958 112.967 -7.638 1.00 12.00 ? 367 PHE B CG 1 ATOM 6251 C CD1 . PHE C 1 315 ? -23.602 113.172 -7.826 1.00 11.98 ? 367 PHE B CD1 1 ATOM 6252 C CD2 . PHE C 1 315 ? -25.623 113.738 -6.693 1.00 13.18 ? 367 PHE B CD2 1 ATOM 6253 C CE1 . PHE C 1 315 ? -22.914 114.123 -7.090 1.00 10.70 ? 367 PHE B CE1 1 ATOM 6254 C CE2 . PHE C 1 315 ? -24.935 114.697 -5.948 1.00 14.35 ? 367 PHE B CE2 1 ATOM 6255 C CZ . PHE C 1 315 ? -23.585 114.886 -6.149 1.00 13.96 ? 367 PHE B CZ 1 ATOM 6256 N N . TYR C 1 316 ? -24.398 113.565 -11.011 1.00 11.88 ? 368 TYR B N 1 ATOM 6257 C CA . TYR C 1 316 ? -23.376 113.711 -12.040 1.00 11.22 ? 368 TYR B CA 1 ATOM 6258 C C . TYR C 1 316 ? -22.072 112.993 -11.722 1.00 11.21 ? 368 TYR B C 1 ATOM 6259 O O . TYR C 1 316 ? -21.682 112.865 -10.561 1.00 11.21 ? 368 TYR B O 1 ATOM 6260 C CB . TYR C 1 316 ? -23.086 115.188 -12.276 1.00 10.50 ? 368 TYR B CB 1 ATOM 6261 C CG . TYR C 1 316 ? -24.071 115.817 -13.238 1.00 12.76 ? 368 TYR B CG 1 ATOM 6262 C CD1 . TYR C 1 316 ? -23.953 115.605 -14.604 1.00 14.01 ? 368 TYR B CD1 1 ATOM 6263 C CD2 . TYR C 1 316 ? -25.128 116.596 -12.781 1.00 13.85 ? 368 TYR B CD2 1 ATOM 6264 C CE1 . TYR C 1 316 ? -24.845 116.167 -15.498 1.00 14.07 ? 368 TYR B CE1 1 ATOM 6265 C CE2 . TYR C 1 316 ? -26.032 117.165 -13.672 1.00 12.55 ? 368 TYR B CE2 1 ATOM 6266 C CZ . TYR C 1 316 ? -25.883 116.942 -15.032 1.00 14.86 ? 368 TYR B CZ 1 ATOM 6267 O OH . TYR C 1 316 ? -26.759 117.499 -15.955 1.00 13.56 ? 368 TYR B OH 1 ATOM 6268 N N . CYS C 1 317 ? -21.413 112.528 -12.778 1.00 12.57 ? 369 CYS B N 1 ATOM 6269 C CA . CYS C 1 317 ? -20.050 112.033 -12.688 1.00 10.63 ? 369 CYS B CA 1 ATOM 6270 C C . CYS C 1 317 ? -19.141 113.188 -12.301 1.00 10.76 ? 369 CYS B C 1 ATOM 6271 O O . CYS C 1 317 ? -19.017 114.164 -13.053 1.00 11.70 ? 369 CYS B O 1 ATOM 6272 C CB . CYS C 1 317 ? -19.584 111.439 -14.021 1.00 13.59 ? 369 CYS B CB 1 ATOM 6273 S SG . CYS C 1 317 ? -20.669 110.186 -14.798 1.00 20.35 ? 369 CYS B SG 1 ATOM 6274 N N . VAL C 1 318 ? -18.525 113.095 -11.127 1.00 9.51 ? 370 VAL B N 1 ATOM 6275 C CA . VAL C 1 318 ? -17.589 114.116 -10.671 1.00 9.03 ? 370 VAL B CA 1 ATOM 6276 C C . VAL C 1 318 ? -16.375 113.475 -10.030 1.00 11.21 ? 370 VAL B C 1 ATOM 6277 O O . VAL C 1 318 ? -16.433 112.340 -9.549 1.00 10.54 ? 370 VAL B O 1 ATOM 6278 C CB . VAL C 1 318 ? -18.238 115.089 -9.641 1.00 11.30 ? 370 VAL B CB 1 ATOM 6279 C CG1 . VAL C 1 318 ? -19.412 115.832 -10.269 1.00 11.29 ? 370 VAL B CG1 1 ATOM 6280 C CG2 . VAL C 1 318 ? -18.668 114.329 -8.373 1.00 11.67 ? 370 VAL B CG2 1 ATOM 6281 N N . ARG C 1 319 ? -15.262 114.197 -10.015 1.00 9.75 ? 371 ARG B N 1 ATOM 6282 C CA . ARG C 1 319 ? -14.114 113.771 -9.243 1.00 9.42 ? 371 ARG B CA 1 ATOM 6283 C C . ARG C 1 319 ? -13.223 114.960 -8.916 1.00 9.29 ? 371 ARG B C 1 ATOM 6284 O O . ARG C 1 319 ? -13.243 115.979 -9.616 1.00 11.49 ? 371 ARG B O 1 ATOM 6285 C CB . ARG C 1 319 ? -13.323 112.696 -9.993 1.00 11.61 ? 371 ARG B CB 1 ATOM 6286 C CG . ARG C 1 319 ? -12.626 113.178 -11.254 1.00 10.65 ? 371 ARG B CG 1 ATOM 6287 C CD . ARG C 1 319 ? -12.035 111.994 -12.027 1.00 14.35 ? 371 ARG B CD 1 ATOM 6288 N NE . ARG C 1 319 ? -13.088 111.073 -12.440 1.00 11.46 ? 371 ARG B NE 1 ATOM 6289 C CZ . ARG C 1 319 ? -12.891 109.877 -12.985 1.00 12.78 ? 371 ARG B CZ 1 ATOM 6290 N NH1 . ARG C 1 319 ? -11.665 109.436 -13.219 1.00 11.31 ? 371 ARG B NH1 1 ATOM 6291 N NH2 . ARG C 1 319 ? -13.941 109.126 -13.309 1.00 12.52 ? 371 ARG B NH2 1 ATOM 6292 N N . PRO C 1 320 ? -12.445 114.849 -7.835 1.00 8.78 ? 372 PRO B N 1 ATOM 6293 C CA . PRO C 1 320 ? -11.514 115.929 -7.518 1.00 10.21 ? 372 PRO B CA 1 ATOM 6294 C C . PRO C 1 320 ? -10.396 116.009 -8.545 1.00 11.11 ? 372 PRO B C 1 ATOM 6295 O O . PRO C 1 320 ? -9.934 114.978 -9.040 1.00 13.07 ? 372 PRO B O 1 ATOM 6296 C CB . PRO C 1 320 ? -10.970 115.543 -6.137 1.00 11.44 ? 372 PRO B CB 1 ATOM 6297 C CG . PRO C 1 320 ? -11.824 114.433 -5.648 1.00 12.63 ? 372 PRO B CG 1 ATOM 6298 C CD . PRO C 1 320 ? -12.322 113.738 -6.880 1.00 12.07 ? 372 PRO B CD 1 ATOM 6299 N N . MET C 1 321 ? -9.973 117.230 -8.864 1.00 11.05 ? 373 MET B N 1 ATOM 6300 C CA . MET C 1 321 ? -8.864 117.462 -9.779 1.00 11.11 ? 373 MET B CA 1 ATOM 6301 C C . MET C 1 321 ? -8.035 118.625 -9.288 1.00 11.04 ? 373 MET B C 1 ATOM 6302 O O . MET C 1 321 ? -8.563 119.558 -8.681 1.00 12.51 ? 373 MET B O 1 ATOM 6303 C CB . MET C 1 321 ? -9.353 117.757 -11.202 1.00 12.37 ? 373 MET B CB 1 ATOM 6304 C CG . MET C 1 321 ? -9.979 116.582 -11.941 1.00 15.12 ? 373 MET B CG 1 ATOM 6305 S SD . MET C 1 321 ? -10.436 117.050 -13.631 1.00 16.21 ? 373 MET B SD 1 ATOM 6306 C CE . MET C 1 321 ? -8.829 117.366 -14.334 1.00 17.25 ? 373 MET B CE 1 ATOM 6307 N N . LYS C 1 322 ? -6.738 118.551 -9.559 1.00 10.82 ? 374 LYS B N 1 ATOM 6308 C CA . LYS C 1 322 ? -5.809 119.664 -9.399 1.00 11.62 ? 374 LYS B CA 1 ATOM 6309 C C . LYS C 1 322 ? -5.083 119.878 -10.711 1.00 11.40 ? 374 LYS B C 1 ATOM 6310 O O . LYS C 1 322 ? -4.654 118.919 -11.354 1.00 12.86 ? 374 LYS B O 1 ATOM 6311 C CB . LYS C 1 322 ? -4.795 119.395 -8.290 1.00 12.51 ? 374 LYS B CB 1 ATOM 6312 C CG . LYS C 1 322 ? -5.379 119.255 -6.918 1.00 11.73 ? 374 LYS B CG 1 ATOM 6313 C CD . LYS C 1 322 ? -4.295 119.181 -5.861 1.00 11.08 ? 374 LYS B CD 1 ATOM 6314 C CE . LYS C 1 322 ? -4.897 119.042 -4.498 1.00 11.00 ? 374 LYS B CE 1 ATOM 6315 N NZ . LYS C 1 322 ? -3.904 119.104 -3.401 1.00 12.05 ? 374 LYS B NZ 1 ATOM 6316 N N . THR C 1 323 ? -4.942 121.140 -11.098 1.00 12.16 ? 375 THR B N 1 ATOM 6317 C CA . THR C 1 323 ? -4.099 121.529 -12.218 1.00 13.97 ? 375 THR B CA 1 ATOM 6318 C C . THR C 1 323 ? -3.281 122.744 -11.816 1.00 12.78 ? 375 THR B C 1 ATOM 6319 O O . THR C 1 323 ? -3.594 123.410 -10.827 1.00 12.48 ? 375 THR B O 1 ATOM 6320 C CB . THR C 1 323 ? -4.920 121.892 -13.456 1.00 14.11 ? 375 THR B CB 1 ATOM 6321 O OG1 . THR C 1 323 ? -5.750 123.012 -13.142 1.00 13.44 ? 375 THR B OG1 1 ATOM 6322 C CG2 . THR C 1 323 ? -5.795 120.729 -13.912 1.00 13.63 ? 375 THR B CG2 1 ATOM 6323 N N . ALA C 1 324 ? -2.254 123.057 -12.590 1.00 12.96 ? 376 ALA B N 1 ATOM 6324 C CA . ALA C 1 324 ? -1.501 124.284 -12.343 1.00 13.35 ? 376 ALA B CA 1 ATOM 6325 C C . ALA C 1 324 ? -2.458 125.474 -12.255 1.00 12.90 ? 376 ALA B C 1 ATOM 6326 O O . ALA C 1 324 ? -2.365 126.296 -11.344 1.00 13.81 ? 376 ALA B O 1 ATOM 6327 C CB . ALA C 1 324 ? -0.466 124.516 -13.432 1.00 15.85 ? 376 ALA B CB 1 ATOM 6328 N N . ALA C 1 325 ? -3.407 125.537 -13.181 1.00 13.20 ? 377 ALA B N 1 ATOM 6329 C CA . ALA C 1 325 ? -4.356 126.644 -13.251 1.00 13.78 ? 377 ALA B CA 1 ATOM 6330 C C . ALA C 1 325 ? -5.316 126.727 -12.062 1.00 15.83 ? 377 ALA B C 1 ATOM 6331 O O . ALA C 1 325 ? -5.845 127.802 -11.772 1.00 18.41 ? 377 ALA B O 1 ATOM 6332 C CB . ALA C 1 325 ? -5.158 126.549 -14.545 1.00 18.32 ? 377 ALA B CB 1 ATOM 6333 N N . SER C 1 326 ? -5.553 125.609 -11.377 1.00 12.27 ? 378 SER B N 1 ATOM 6334 C CA . SER C 1 326 ? -6.483 125.598 -10.248 1.00 12.02 ? 378 SER B CA 1 ATOM 6335 C C . SER C 1 326 ? -5.805 125.998 -8.925 1.00 11.32 ? 378 SER B C 1 ATOM 6336 O O . SER C 1 326 ? -6.431 125.924 -7.866 1.00 12.25 ? 378 SER B O 1 ATOM 6337 C CB . SER C 1 326 ? -7.140 124.214 -10.092 1.00 12.58 ? 378 SER B CB 1 ATOM 6338 O OG . SER C 1 326 ? -6.250 123.263 -9.535 1.00 12.09 ? 378 SER B OG 1 ATOM 6339 N N . SER C 1 327 ? -4.549 126.444 -8.991 1.00 11.49 ? 379 SER B N 1 ATOM 6340 C CA . SER C 1 327 ? -3.761 126.673 -7.781 1.00 11.92 ? 379 SER B CA 1 ATOM 6341 C C . SER C 1 327 ? -4.219 127.841 -6.909 1.00 18.21 ? 379 SER B C 1 ATOM 6342 O O . SER C 1 327 ? -3.702 128.017 -5.805 1.00 17.30 ? 379 SER B O 1 ATOM 6343 C CB . SER C 1 327 ? -2.302 126.894 -8.153 1.00 11.59 ? 379 SER B CB 1 ATOM 6344 O OG . SER C 1 327 ? -1.735 125.733 -8.728 1.00 13.20 ? 379 SER B OG 1 ATOM 6345 N N . ASN C 1 328 ? -5.163 128.635 -7.404 1.00 15.94 ? 380 ASN B N 1 ATOM 6346 C CA . ASN C 1 328 ? -5.784 129.689 -6.610 1.00 16.83 ? 380 ASN B CA 1 ATOM 6347 C C . ASN C 1 328 ? -6.985 129.198 -5.801 1.00 16.15 ? 380 ASN B C 1 ATOM 6348 O O . ASN C 1 328 ? -7.455 129.874 -4.889 1.00 15.70 ? 380 ASN B O 1 ATOM 6349 C CB . ASN C 1 328 ? -6.218 130.838 -7.527 1.00 20.98 ? 380 ASN B CB 1 ATOM 6350 C CG . ASN C 1 328 ? -7.201 130.387 -8.618 1.00 24.51 ? 380 ASN B CG 1 ATOM 6351 O OD1 . ASN C 1 328 ? -6.968 129.397 -9.336 1.00 21.09 ? 380 ASN B OD1 1 ATOM 6352 N ND2 . ASN C 1 328 ? -8.311 131.109 -8.738 1.00 27.69 ? 380 ASN B ND2 1 ATOM 6353 N N . MET C 1 329 ? -7.473 128.002 -6.121 1.00 11.76 ? 381 MET B N 1 ATOM 6354 C CA . MET C 1 329 ? -8.669 127.473 -5.483 1.00 12.12 ? 381 MET B CA 1 ATOM 6355 C C . MET C 1 329 ? -8.319 126.610 -4.281 1.00 13.46 ? 381 MET B C 1 ATOM 6356 O O . MET C 1 329 ? -7.272 125.962 -4.270 1.00 14.46 ? 381 MET B O 1 ATOM 6357 C CB . MET C 1 329 ? -9.497 126.664 -6.488 1.00 15.12 ? 381 MET B CB 1 ATOM 6358 C CG . MET C 1 329 ? -9.952 127.453 -7.700 1.00 16.52 ? 381 MET B CG 1 ATOM 6359 S SD . MET C 1 329 ? -10.764 129.005 -7.278 1.00 17.88 ? 381 MET B SD 1 ATOM 6360 C CE . MET C 1 329 ? -12.084 128.437 -6.217 1.00 17.96 ? 381 MET B CE 1 ATOM 6361 N N . VAL C 1 330 ? -9.206 126.604 -3.292 1.00 11.65 ? 382 VAL B N 1 ATOM 6362 C CA . VAL C 1 330 ? -9.019 125.838 -2.066 1.00 12.11 ? 382 VAL B CA 1 ATOM 6363 C C . VAL C 1 330 ? -10.309 125.139 -1.705 1.00 12.02 ? 382 VAL B C 1 ATOM 6364 O O . VAL C 1 330 ? -11.357 125.777 -1.587 1.00 12.21 ? 382 VAL B O 1 ATOM 6365 C CB . VAL C 1 330 ? -8.606 126.726 -0.866 1.00 13.31 ? 382 VAL B CB 1 ATOM 6366 C CG1 . VAL C 1 330 ? -8.053 125.859 0.270 1.00 12.07 ? 382 VAL B CG1 1 ATOM 6367 C CG2 . VAL C 1 330 ? -7.611 127.777 -1.289 1.00 15.14 ? 382 VAL B CG2 1 ATOM 6368 N N . TYR C 1 331 ? -10.231 123.826 -1.524 1.00 11.13 ? 383 TYR B N 1 ATOM 6369 C CA . TYR C 1 331 ? -11.362 123.042 -1.043 1.00 12.03 ? 383 TYR B CA 1 ATOM 6370 C C . TYR C 1 331 ? -11.312 123.016 0.484 1.00 11.02 ? 383 TYR B C 1 ATOM 6371 O O . TYR C 1 331 ? -10.349 122.536 1.073 1.00 11.50 ? 383 TYR B O 1 ATOM 6372 C CB . TYR C 1 331 ? -11.333 121.622 -1.614 1.00 10.92 ? 383 TYR B CB 1 ATOM 6373 C CG . TYR C 1 331 ? -12.565 120.797 -1.289 1.00 11.21 ? 383 TYR B CG 1 ATOM 6374 C CD1 . TYR C 1 331 ? -12.637 120.052 -0.120 1.00 10.48 ? 383 TYR B CD1 1 ATOM 6375 C CD2 . TYR C 1 331 ? -13.657 120.755 -2.154 1.00 10.92 ? 383 TYR B CD2 1 ATOM 6376 C CE1 . TYR C 1 331 ? -13.758 119.295 0.188 1.00 10.13 ? 383 TYR B CE1 1 ATOM 6377 C CE2 . TYR C 1 331 ? -14.781 120.004 -1.852 1.00 11.29 ? 383 TYR B CE2 1 ATOM 6378 C CZ . TYR C 1 331 ? -14.830 119.277 -0.676 1.00 9.80 ? 383 TYR B CZ 1 ATOM 6379 O OH . TYR C 1 331 ? -15.949 118.525 -0.374 1.00 10.65 ? 383 TYR B OH 1 ATOM 6380 N N . VAL C 1 332 ? -12.351 123.564 1.103 1.00 11.64 ? 384 VAL B N 1 ATOM 6381 C CA . VAL C 1 332 ? -12.404 123.803 2.541 1.00 13.50 ? 384 VAL B CA 1 ATOM 6382 C C . VAL C 1 332 ? -13.593 123.070 3.162 1.00 14.26 ? 384 VAL B C 1 ATOM 6383 O O . VAL C 1 332 ? -14.724 123.256 2.712 1.00 15.41 ? 384 VAL B O 1 ATOM 6384 C CB . VAL C 1 332 ? -12.529 125.326 2.804 1.00 18.33 ? 384 VAL B CB 1 ATOM 6385 C CG1 . VAL C 1 332 ? -12.646 125.632 4.272 1.00 22.95 ? 384 VAL B CG1 1 ATOM 6386 C CG2 . VAL C 1 332 ? -11.339 126.057 2.192 1.00 19.25 ? 384 VAL B CG2 1 ATOM 6387 N N . THR C 1 333 ? -13.372 122.242 4.182 1.00 12.94 ? 385 THR B N 1 ATOM 6388 C CA . THR C 1 333 ? -14.502 121.616 4.854 1.00 15.29 ? 385 THR B CA 1 ATOM 6389 C C . THR C 1 333 ? -14.990 122.524 5.986 1.00 13.71 ? 385 THR B C 1 ATOM 6390 O O . THR C 1 333 ? -14.292 123.452 6.414 1.00 14.00 ? 385 THR B O 1 ATOM 6391 C CB . THR C 1 333 ? -14.171 120.210 5.407 1.00 14.87 ? 385 THR B CB 1 ATOM 6392 O OG1 . THR C 1 333 ? -13.357 120.319 6.576 1.00 16.45 ? 385 THR B OG1 1 ATOM 6393 C CG2 . THR C 1 333 ? -13.444 119.372 4.349 1.00 13.54 ? 385 THR B CG2 1 ATOM 6394 N N . SER C 1 334 ? -16.201 122.248 6.450 1.00 13.48 ? 386 SER B N 1 ATOM 6395 C CA . SER C 1 334 ? -16.845 123.054 7.470 1.00 12.85 ? 386 SER B CA 1 ATOM 6396 C C . SER C 1 334 ? -16.032 122.999 8.765 1.00 16.44 ? 386 SER B C 1 ATOM 6397 O O . SER C 1 334 ? -16.049 123.932 9.565 1.00 18.52 ? 386 SER B O 1 ATOM 6398 C CB . SER C 1 334 ? -18.273 122.557 7.699 1.00 14.81 ? 386 SER B CB 1 ATOM 6399 O OG . SER C 1 334 ? -19.035 123.518 8.411 1.00 15.49 ? 386 SER B OG 1 ATOM 6400 N N . HIS C 1 335 ? -15.313 121.895 8.955 1.00 13.12 ? 387 HIS B N 1 ATOM 6401 C CA . HIS C 1 335 ? -14.511 121.681 10.160 1.00 14.57 ? 387 HIS B CA 1 ATOM 6402 C C . HIS C 1 335 ? -13.018 121.831 9.880 1.00 14.02 ? 387 HIS B C 1 ATOM 6403 O O . HIS C 1 335 ? -12.220 120.928 10.147 1.00 18.72 ? 387 HIS B O 1 ATOM 6404 C CB . HIS C 1 335 ? -14.816 120.304 10.742 1.00 15.59 ? 387 HIS B CB 1 ATOM 6405 C CG . HIS C 1 335 ? -16.230 120.155 11.204 1.00 15.02 ? 387 HIS B CG 1 ATOM 6406 N ND1 . HIS C 1 335 ? -17.199 119.536 10.448 1.00 15.52 ? 387 HIS B ND1 1 ATOM 6407 C CD2 . HIS C 1 335 ? -16.845 120.567 12.338 1.00 16.46 ? 387 HIS B CD2 1 ATOM 6408 C CE1 . HIS C 1 335 ? -18.345 119.550 11.105 1.00 17.17 ? 387 HIS B CE1 1 ATOM 6409 N NE2 . HIS C 1 335 ? -18.159 120.176 12.253 1.00 15.96 ? 387 HIS B NE2 1 ATOM 6410 N N . THR C 1 336 ? -12.648 122.982 9.337 1.00 14.81 ? 388 THR B N 1 ATOM 6411 C CA . THR C 1 336 ? -11.261 123.329 9.106 1.00 12.25 ? 388 THR B CA 1 ATOM 6412 C C . THR C 1 336 ? -10.638 123.743 10.434 1.00 15.57 ? 388 THR B C 1 ATOM 6413 O O . THR C 1 336 ? -11.282 124.453 11.213 1.00 17.38 ? 388 THR B O 1 ATOM 6414 C CB . THR C 1 336 ? -11.155 124.463 8.065 1.00 14.37 ? 388 THR B CB 1 ATOM 6415 O OG1 . THR C 1 336 ? -11.622 123.980 6.799 1.00 14.39 ? 388 THR B OG1 1 ATOM 6416 C CG2 . THR C 1 336 ? -9.745 124.946 7.904 1.00 14.20 ? 388 THR B CG2 1 ATOM 6417 N N . ARG C 1 337 ? -9.412 123.299 10.707 1.00 14.82 ? 389 ARG B N 1 ATOM 6418 C CA . ARG C 1 337 ? -8.785 123.597 11.995 1.00 14.44 ? 389 ARG B CA 1 ATOM 6419 C C . ARG C 1 337 ? -8.201 125.003 11.986 1.00 14.38 ? 389 ARG B C 1 ATOM 6420 O O . ARG C 1 337 ? -7.585 125.427 11.009 1.00 15.56 ? 389 ARG B O 1 ATOM 6421 C CB . ARG C 1 337 ? -7.714 122.549 12.352 1.00 13.95 ? 389 ARG B CB 1 ATOM 6422 C CG . ARG C 1 337 ? -6.593 122.343 11.350 1.00 13.99 ? 389 ARG B CG 1 ATOM 6423 C CD . ARG C 1 337 ? -5.729 121.125 11.776 1.00 16.01 ? 389 ARG B CD 1 ATOM 6424 N NE . ARG C 1 337 ? -5.252 121.287 13.152 1.00 14.34 ? 389 ARG B NE 1 ATOM 6425 C CZ . ARG C 1 337 ? -4.894 120.298 13.966 1.00 16.35 ? 389 ARG B CZ 1 ATOM 6426 N NH1 . ARG C 1 337 ? -4.921 119.030 13.566 1.00 17.07 ? 389 ARG B NH1 1 ATOM 6427 N NH2 . ARG C 1 337 ? -4.494 120.589 15.198 1.00 17.59 ? 389 ARG B NH2 1 ATOM 6428 N N . PRO C 1 338 ? -8.414 125.752 13.084 1.00 14.53 ? 390 PRO B N 1 ATOM 6429 C CA . PRO C 1 338 ? -8.025 127.168 13.098 1.00 16.50 ? 390 PRO B CA 1 ATOM 6430 C C . PRO C 1 338 ? -6.524 127.384 13.177 1.00 18.48 ? 390 PRO B C 1 ATOM 6431 O O . PRO C 1 338 ? -6.055 128.491 12.916 1.00 22.39 ? 390 PRO B O 1 ATOM 6432 C CB . PRO C 1 338 ? -8.725 127.711 14.351 1.00 19.49 ? 390 PRO B CB 1 ATOM 6433 C CG . PRO C 1 338 ? -8.983 126.549 15.199 1.00 19.08 ? 390 PRO B CG 1 ATOM 6434 C CD . PRO C 1 338 ? -9.179 125.376 14.283 1.00 17.06 ? 390 PRO B CD 1 ATOM 6435 N N . ASP C 1 339 ? -5.781 126.338 13.523 1.00 14.89 ? 391 ASP B N 1 ATOM 6436 C CA . ASP C 1 339 ? -4.334 126.396 13.555 1.00 14.68 ? 391 ASP B CA 1 ATOM 6437 C C . ASP C 1 339 ? -3.714 125.800 12.285 1.00 14.73 ? 391 ASP B C 1 ATOM 6438 O O . ASP C 1 339 ? -2.578 125.351 12.308 1.00 15.46 ? 391 ASP B O 1 ATOM 6439 C CB . ASP C 1 339 ? -3.806 125.648 14.785 1.00 13.95 ? 391 ASP B CB 1 ATOM 6440 C CG . ASP C 1 339 ? -4.372 124.243 14.906 1.00 18.16 ? 391 ASP B CG 1 ATOM 6441 O OD1 . ASP C 1 339 ? -5.153 123.835 14.018 1.00 17.56 ? 391 ASP B OD1 1 ATOM 6442 O OD2 . ASP C 1 339 ? -4.047 123.534 15.885 1.00 17.01 ? 391 ASP B OD2 1 ATOM 6443 N N . HIS C 1 340 ? -4.445 125.815 11.173 1.00 15.01 ? 392 HIS B N 1 ATOM 6444 C CA . HIS C 1 340 ? -3.981 125.110 9.981 1.00 16.47 ? 392 HIS B CA 1 ATOM 6445 C C . HIS C 1 340 ? -2.648 125.636 9.422 1.00 14.48 ? 392 HIS B C 1 ATOM 6446 O O . HIS C 1 340 ? -1.903 124.884 8.791 1.00 15.82 ? 392 HIS B O 1 ATOM 6447 C CB . HIS C 1 340 ? -5.060 125.145 8.888 1.00 16.19 ? 392 HIS B CB 1 ATOM 6448 C CG . HIS C 1 340 ? -5.331 126.507 8.331 1.00 15.22 ? 392 HIS B CG 1 ATOM 6449 N ND1 . HIS C 1 340 ? -4.712 126.984 7.194 1.00 16.48 ? 392 HIS B ND1 1 ATOM 6450 C CD2 . HIS C 1 340 ? -6.164 127.492 8.747 1.00 17.30 ? 392 HIS B CD2 1 ATOM 6451 C CE1 . HIS C 1 340 ? -5.151 128.202 6.935 1.00 19.39 ? 392 HIS B CE1 1 ATOM 6452 N NE2 . HIS C 1 340 ? -6.029 128.536 7.864 1.00 19.47 ? 392 HIS B NE2 1 ATOM 6453 N N . GLU C 1 341 ? -2.311 126.905 9.653 1.00 15.83 ? 393 GLU B N 1 ATOM 6454 C CA . GLU C 1 341 ? -1.061 127.426 9.110 1.00 16.50 ? 393 GLU B CA 1 ATOM 6455 C C . GLU C 1 341 ? 0.169 126.739 9.722 1.00 13.49 ? 393 GLU B C 1 ATOM 6456 O O . GLU C 1 341 ? 1.207 126.647 9.073 1.00 16.29 ? 393 GLU B O 1 ATOM 6457 C CB . GLU C 1 341 ? -0.959 128.943 9.313 1.00 17.61 ? 393 GLU B CB 1 ATOM 6458 C CG . GLU C 1 341 ? -1.936 129.743 8.462 1.00 23.22 ? 393 GLU B CG 1 ATOM 6459 C CD . GLU C 1 341 ? -3.228 130.074 9.192 1.00 36.61 ? 393 GLU B CD 1 ATOM 6460 O OE1 . GLU C 1 341 ? -3.554 129.390 10.194 1.00 30.36 ? 393 GLU B OE1 1 ATOM 6461 O OE2 . GLU C 1 341 ? -3.915 131.034 8.766 1.00 33.51 ? 393 GLU B OE2 1 ATOM 6462 N N . THR C 1 342 ? 0.044 126.243 10.954 1.00 15.17 ? 394 THR B N 1 ATOM 6463 C CA . THR C 1 342 ? 1.152 125.547 11.618 1.00 17.37 ? 394 THR B CA 1 ATOM 6464 C C . THR C 1 342 ? 0.963 124.029 11.701 1.00 13.67 ? 394 THR B C 1 ATOM 6465 O O . THR C 1 342 ? 1.876 123.321 12.118 1.00 15.28 ? 394 THR B O 1 ATOM 6466 C CB . THR C 1 342 ? 1.367 126.092 13.048 1.00 17.96 ? 394 THR B CB 1 ATOM 6467 O OG1 . THR C 1 342 ? 0.174 125.920 13.818 1.00 17.91 ? 394 THR B OG1 1 ATOM 6468 C CG2 . THR C 1 342 ? 1.720 127.567 12.992 1.00 18.11 ? 394 THR B CG2 1 ATOM 6469 N N . LYS C 1 343 ? -0.209 123.535 11.298 1.00 13.61 ? 395 LYS B N 1 ATOM 6470 C CA . LYS C 1 343 ? -0.531 122.105 11.389 1.00 13.10 ? 395 LYS B CA 1 ATOM 6471 C C . LYS C 1 343 ? -0.713 121.441 10.026 1.00 14.03 ? 395 LYS B C 1 ATOM 6472 O O . LYS C 1 343 ? -0.762 120.212 9.934 1.00 15.34 ? 395 LYS B O 1 ATOM 6473 C CB . LYS C 1 343 ? -1.803 121.911 12.211 1.00 15.86 ? 395 LYS B CB 1 ATOM 6474 C CG . LYS C 1 343 ? -1.609 122.165 13.704 1.00 17.18 ? 395 LYS B CG 1 ATOM 6475 C CD . LYS C 1 343 ? -0.842 121.006 14.341 1.00 20.46 ? 395 LYS B CD 1 ATOM 6476 C CE . LYS C 1 343 ? -0.651 121.198 15.822 1.00 23.73 ? 395 LYS B CE 1 ATOM 6477 N NZ . LYS C 1 343 ? 0.086 120.036 16.382 1.00 21.93 ? 395 LYS B NZ 1 ATOM 6478 N N . CYS C 1 344 ? -0.808 122.256 8.978 1.00 14.04 ? 396 CYS B N 1 ATOM 6479 C CA . CYS C 1 344 ? -1.110 121.774 7.628 1.00 12.16 ? 396 CYS B CA 1 ATOM 6480 C C . CYS C 1 344 ? -0.135 122.332 6.602 1.00 12.15 ? 396 CYS B C 1 ATOM 6481 O O . CYS C 1 344 ? 0.493 123.355 6.831 1.00 12.85 ? 396 CYS B O 1 ATOM 6482 C CB . CYS C 1 344 ? -2.527 122.166 7.222 1.00 14.52 ? 396 CYS B CB 1 ATOM 6483 S SG . CYS C 1 344 ? -3.813 121.658 8.365 1.00 15.42 ? 396 CYS B SG 1 ATOM 6484 N N . PRO C 1 345 ? -0.012 121.673 5.444 1.00 11.75 ? 397 PRO B N 1 ATOM 6485 C CA . PRO C 1 345 ? 0.889 122.190 4.415 1.00 12.22 ? 397 PRO B CA 1 ATOM 6486 C C . PRO C 1 345 ? 0.425 123.502 3.798 1.00 11.67 ? 397 PRO B C 1 ATOM 6487 O O . PRO C 1 345 ? -0.787 123.766 3.740 1.00 12.70 ? 397 PRO B O 1 ATOM 6488 C CB . PRO C 1 345 ? 0.889 121.078 3.358 1.00 12.57 ? 397 PRO B CB 1 ATOM 6489 C CG . PRO C 1 345 ? 0.413 119.866 4.086 1.00 11.12 ? 397 PRO B CG 1 ATOM 6490 C CD . PRO C 1 345 ? -0.583 120.370 5.064 1.00 12.57 ? 397 PRO B CD 1 ATOM 6491 N N . PRO C 1 346 ? 1.374 124.307 3.306 1.00 12.79 ? 398 PRO B N 1 ATOM 6492 C CA . PRO C 1 346 ? 1.015 125.535 2.604 1.00 14.49 ? 398 PRO B CA 1 ATOM 6493 C C . PRO C 1 346 ? 0.564 125.250 1.185 1.00 14.72 ? 398 PRO B C 1 ATOM 6494 O O . PRO C 1 346 ? 0.649 124.121 0.689 1.00 13.04 ? 398 PRO B O 1 ATOM 6495 C CB . PRO C 1 346 ? 2.317 126.324 2.617 1.00 15.11 ? 398 PRO B CB 1 ATOM 6496 C CG . PRO C 1 346 ? 3.371 125.271 2.538 1.00 16.34 ? 398 PRO B CG 1 ATOM 6497 C CD . PRO C 1 346 ? 2.835 124.106 3.330 1.00 13.93 ? 398 PRO B CD 1 ATOM 6498 N N . ARG C 1 347 ? 0.092 126.293 0.527 1.00 13.20 ? 399 ARG B N 1 ATOM 6499 C CA . ARG C 1 347 ? -0.384 126.184 -0.834 1.00 13.28 ? 399 ARG B CA 1 ATOM 6500 C C . ARG C 1 347 ? 0.704 125.788 -1.826 1.00 13.80 ? 399 ARG B C 1 ATOM 6501 O O . ARG C 1 347 ? 0.479 124.966 -2.718 1.00 14.06 ? 399 ARG B O 1 ATOM 6502 C CB . ARG C 1 347 ? -1.002 127.519 -1.241 1.00 14.27 ? 399 ARG B CB 1 ATOM 6503 C CG . ARG C 1 347 ? -1.560 127.561 -2.642 1.00 17.61 ? 399 ARG B CG 1 ATOM 6504 C CD . ARG C 1 347 ? -2.242 128.903 -2.899 1.00 20.71 ? 399 ARG B CD 1 ATOM 6505 N NE . ARG C 1 347 ? -1.259 129.951 -3.141 1.00 23.59 ? 399 ARG B NE 1 ATOM 6506 C CZ . ARG C 1 347 ? -0.947 130.443 -4.336 1.00 22.13 ? 399 ARG B CZ 1 ATOM 6507 N NH1 . ARG C 1 347 ? -1.550 130.009 -5.435 1.00 25.39 ? 399 ARG B NH1 1 ATOM 6508 N NH2 . ARG C 1 347 ? -0.025 131.388 -4.427 1.00 26.23 ? 399 ARG B NH2 1 ATOM 6509 N N . GLU C 1 348 ? 1.883 126.380 -1.692 1.00 11.49 ? 400 GLU B N 1 ATOM 6510 C CA . GLU C 1 348 ? 2.893 126.268 -2.725 1.00 11.71 ? 400 GLU B CA 1 ATOM 6511 C C . GLU C 1 348 ? 3.760 125.021 -2.549 1.00 11.95 ? 400 GLU B C 1 ATOM 6512 O O . GLU C 1 348 ? 4.113 124.670 -1.422 1.00 13.38 ? 400 GLU B O 1 ATOM 6513 C CB . GLU C 1 348 ? 3.795 127.507 -2.725 1.00 14.72 ? 400 GLU B CB 1 ATOM 6514 C CG . GLU C 1 348 ? 3.049 128.841 -2.823 1.00 15.95 ? 400 GLU B CG 1 ATOM 6515 C CD . GLU C 1 348 ? 2.652 129.428 -1.470 1.00 19.51 ? 400 GLU B CD 1 ATOM 6516 O OE1 . GLU C 1 348 ? 2.765 128.742 -0.434 1.00 17.30 ? 400 GLU B OE1 1 ATOM 6517 O OE2 . GLU C 1 348 ? 2.217 130.601 -1.450 1.00 25.68 ? 400 GLU B OE2 1 ATOM 6518 N N . PRO C 1 349 ? 4.145 124.378 -3.671 1.00 11.13 ? 401 PRO B N 1 ATOM 6519 C CA . PRO C 1 349 ? 5.211 123.378 -3.595 1.00 12.08 ? 401 PRO B CA 1 ATOM 6520 C C . PRO C 1 349 ? 6.479 124.015 -3.047 1.00 12.34 ? 401 PRO B C 1 ATOM 6521 O O . PRO C 1 349 ? 6.616 125.244 -3.072 1.00 13.00 ? 401 PRO B O 1 ATOM 6522 C CB . PRO C 1 349 ? 5.393 122.926 -5.048 1.00 13.79 ? 401 PRO B CB 1 ATOM 6523 C CG . PRO C 1 349 ? 4.133 123.288 -5.733 1.00 13.20 ? 401 PRO B CG 1 ATOM 6524 C CD . PRO C 1 349 ? 3.639 124.530 -5.046 1.00 11.43 ? 401 PRO B CD 1 ATOM 6525 N N . LEU C 1 350 ? 7.381 123.190 -2.532 1.00 12.03 ? 402 LEU B N 1 ATOM 6526 C CA . LEU C 1 350 ? 8.639 123.672 -1.979 1.00 10.39 ? 402 LEU B CA 1 ATOM 6527 C C . LEU C 1 350 ? 9.745 123.510 -3.009 1.00 11.89 ? 402 LEU B C 1 ATOM 6528 O O . LEU C 1 350 ? 10.083 122.392 -3.380 1.00 13.20 ? 402 LEU B O 1 ATOM 6529 C CB . LEU C 1 350 ? 8.984 122.912 -0.698 1.00 12.44 ? 402 LEU B CB 1 ATOM 6530 C CG . LEU C 1 350 ? 7.865 122.854 0.332 1.00 14.09 ? 402 LEU B CG 1 ATOM 6531 C CD1 . LEU C 1 350 ? 8.264 121.960 1.487 1.00 14.63 ? 402 LEU B CD1 1 ATOM 6532 C CD2 . LEU C 1 350 ? 7.520 124.264 0.809 1.00 16.18 ? 402 LEU B CD2 1 ATOM 6533 N N . LYS C 1 351 ? 10.314 124.616 -3.489 1.00 11.65 ? 403 LYS B N 1 ATOM 6534 C CA . LYS C 1 351 ? 11.358 124.528 -4.504 1.00 12.29 ? 403 LYS B CA 1 ATOM 6535 C C . LYS C 1 351 ? 12.717 124.125 -3.921 1.00 11.21 ? 403 LYS B C 1 ATOM 6536 O O . LYS C 1 351 ? 13.052 124.455 -2.773 1.00 12.65 ? 403 LYS B O 1 ATOM 6537 C CB . LYS C 1 351 ? 11.498 125.860 -5.263 1.00 13.40 ? 403 LYS B CB 1 ATOM 6538 C CG . LYS C 1 351 ? 12.022 127.023 -4.427 1.00 16.45 ? 403 LYS B CG 1 ATOM 6539 C CD . LYS C 1 351 ? 12.306 128.226 -5.320 1.00 16.07 ? 403 LYS B CD 1 ATOM 6540 C CE . LYS C 1 351 ? 13.018 129.336 -4.558 1.00 16.79 ? 403 LYS B CE 1 ATOM 6541 N NZ . LYS C 1 351 ? 13.532 130.388 -5.477 1.00 21.85 ? 403 LYS B NZ 1 ATOM 6542 N N . ASN C 1 352 ? 13.477 123.386 -4.725 1.00 13.51 ? 404 ASN B N 1 ATOM 6543 C CA . ASN C 1 352 ? 14.868 123.076 -4.456 1.00 14.11 ? 404 ASN B CA 1 ATOM 6544 C C . ASN C 1 352 ? 15.106 122.324 -3.155 1.00 13.87 ? 404 ASN B C 1 ATOM 6545 O O . ASN C 1 352 ? 16.149 122.474 -2.525 1.00 14.87 ? 404 ASN B O 1 ATOM 6546 C CB . ASN C 1 352 ? 15.697 124.368 -4.477 1.00 15.92 ? 404 ASN B CB 1 ATOM 6547 C CG . ASN C 1 352 ? 15.725 125.014 -5.853 1.00 17.30 ? 404 ASN B CG 1 ATOM 6548 O OD1 . ASN C 1 352 ? 16.246 124.439 -6.808 1.00 21.14 ? 404 ASN B OD1 1 ATOM 6549 N ND2 . ASN C 1 352 ? 15.150 126.203 -5.966 1.00 16.43 ? 404 ASN B ND2 1 ATOM 6550 N N . VAL C 1 353 ? 14.154 121.478 -2.769 1.00 12.15 ? 405 VAL B N 1 ATOM 6551 C CA . VAL C 1 353 ? 14.358 120.619 -1.611 1.00 12.42 ? 405 VAL B CA 1 ATOM 6552 C C . VAL C 1 353 ? 13.815 119.219 -1.859 1.00 12.47 ? 405 VAL B C 1 ATOM 6553 O O . VAL C 1 353 ? 13.023 118.999 -2.782 1.00 13.65 ? 405 VAL B O 1 ATOM 6554 C CB . VAL C 1 353 ? 13.718 121.203 -0.322 1.00 14.12 ? 405 VAL B CB 1 ATOM 6555 C CG1 . VAL C 1 353 ? 14.550 122.392 0.209 1.00 13.75 ? 405 VAL B CG1 1 ATOM 6556 C CG2 . VAL C 1 353 ? 12.264 121.595 -0.543 1.00 14.31 ? 405 VAL B CG2 1 ATOM 6557 N N . ARG C 1 354 ? 14.283 118.297 -1.021 1.00 11.89 ? 406 ARG B N 1 ATOM 6558 C CA . ARG C 1 354 ? 13.942 116.876 -1.061 1.00 13.93 ? 406 ARG B CA 1 ATOM 6559 C C . ARG C 1 354 ? 13.477 116.450 0.332 1.00 14.05 ? 406 ARG B C 1 ATOM 6560 O O . ARG C 1 354 ? 14.137 116.749 1.322 1.00 13.49 ? 406 ARG B O 1 ATOM 6561 C CB . ARG C 1 354 ? 15.160 116.033 -1.465 1.00 16.41 ? 406 ARG B CB 1 ATOM 6562 C CG . ARG C 1 354 ? 15.832 116.423 -2.774 1.00 13.81 ? 406 ARG B CG 1 ATOM 6563 C CD . ARG C 1 354 ? 17.310 116.027 -2.792 1.00 18.13 ? 406 ARG B CD 1 ATOM 6564 N NE . ARG C 1 354 ? 17.498 114.590 -2.635 1.00 19.28 ? 406 ARG B NE 1 ATOM 6565 C CZ . ARG C 1 354 ? 18.652 114.007 -2.323 1.00 20.54 ? 406 ARG B CZ 1 ATOM 6566 N NH1 . ARG C 1 354 ? 19.742 114.731 -2.110 1.00 24.19 ? 406 ARG B NH1 1 ATOM 6567 N NH2 . ARG C 1 354 ? 18.707 112.685 -2.209 1.00 21.91 ? 406 ARG B NH2 1 ATOM 6568 N N . TRP C 1 355 ? 12.370 115.720 0.428 1.00 11.02 ? 407 TRP B N 1 ATOM 6569 C CA . TRP C 1 355 ? 11.934 115.207 1.725 1.00 11.71 ? 407 TRP B CA 1 ATOM 6570 C C . TRP C 1 355 ? 12.950 114.256 2.344 1.00 12.58 ? 407 TRP B C 1 ATOM 6571 O O . TRP C 1 355 ? 13.487 113.389 1.659 1.00 13.50 ? 407 TRP B O 1 ATOM 6572 C CB . TRP C 1 355 ? 10.611 114.456 1.602 1.00 11.09 ? 407 TRP B CB 1 ATOM 6573 C CG . TRP C 1 355 ? 9.469 115.249 1.057 1.00 11.22 ? 407 TRP B CG 1 ATOM 6574 C CD1 . TRP C 1 355 ? 8.891 115.121 -0.172 1.00 10.97 ? 407 TRP B CD1 1 ATOM 6575 C CD2 . TRP C 1 355 ? 8.751 116.292 1.730 1.00 11.00 ? 407 TRP B CD2 1 ATOM 6576 N NE1 . TRP C 1 355 ? 7.856 116.017 -0.303 1.00 10.68 ? 407 TRP B NE1 1 ATOM 6577 C CE2 . TRP C 1 355 ? 7.747 116.745 0.852 1.00 12.08 ? 407 TRP B CE2 1 ATOM 6578 C CE3 . TRP C 1 355 ? 8.855 116.880 2.996 1.00 12.53 ? 407 TRP B CE3 1 ATOM 6579 C CZ2 . TRP C 1 355 ? 6.859 117.772 1.191 1.00 11.08 ? 407 TRP B CZ2 1 ATOM 6580 C CZ3 . TRP C 1 355 ? 7.970 117.890 3.337 1.00 11.52 ? 407 TRP B CZ3 1 ATOM 6581 C CH2 . TRP C 1 355 ? 6.984 118.327 2.443 1.00 12.47 ? 407 TRP B CH2 1 ATOM 6582 N N . GLY C 1 356 ? 13.177 114.392 3.645 1.00 13.02 ? 408 GLY B N 1 ATOM 6583 C CA . GLY C 1 356 ? 14.076 113.495 4.349 1.00 13.62 ? 408 GLY B CA 1 ATOM 6584 C C . GLY C 1 356 ? 13.688 113.220 5.787 1.00 12.23 ? 408 GLY B C 1 ATOM 6585 O O . GLY C 1 356 ? 12.684 113.719 6.302 1.00 12.22 ? 408 GLY B O 1 ATOM 6586 N N . VAL C 1 357 ? 14.508 112.393 6.429 1.00 13.24 ? 409 VAL B N 1 ATOM 6587 C CA . VAL C 1 357 ? 14.436 112.165 7.863 1.00 13.95 ? 409 VAL B CA 1 ATOM 6588 C C . VAL C 1 357 ? 15.826 112.433 8.435 1.00 13.11 ? 409 VAL B C 1 ATOM 6589 O O . VAL C 1 357 ? 16.817 112.402 7.705 1.00 13.80 ? 409 VAL B O 1 ATOM 6590 C CB . VAL C 1 357 ? 13.966 110.734 8.207 1.00 14.59 ? 409 VAL B CB 1 ATOM 6591 C CG1 . VAL C 1 357 ? 12.524 110.538 7.750 1.00 13.74 ? 409 VAL B CG1 1 ATOM 6592 C CG2 . VAL C 1 357 ? 14.884 109.705 7.571 1.00 17.55 ? 409 VAL B CG2 1 ATOM 6593 N N . VAL C 1 358 ? 15.888 112.725 9.728 1.00 14.31 ? 410 VAL B N 1 ATOM 6594 C CA . VAL C 1 358 ? 17.144 113.105 10.359 1.00 13.65 ? 410 VAL B CA 1 ATOM 6595 C C . VAL C 1 358 ? 18.073 111.905 10.444 1.00 16.44 ? 410 VAL B C 1 ATOM 6596 O O . VAL C 1 358 ? 17.645 110.774 10.715 1.00 17.12 ? 410 VAL B O 1 ATOM 6597 C CB . VAL C 1 358 ? 16.900 113.699 11.761 1.00 15.15 ? 410 VAL B CB 1 ATOM 6598 C CG1 . VAL C 1 358 ? 18.213 113.962 12.496 1.00 18.60 ? 410 VAL B CG1 1 ATOM 6599 C CG2 . VAL C 1 358 ? 16.099 114.991 11.657 1.00 18.69 ? 410 VAL B CG2 1 ATOM 6600 N N . SER C 1 359 ? 19.348 112.164 10.186 1.00 16.72 ? 411 SER B N 1 ATOM 6601 C CA . SER C 1 359 ? 20.377 111.139 10.264 1.00 17.66 ? 411 SER B CA 1 ATOM 6602 C C . SER C 1 359 ? 21.527 111.667 11.102 1.00 19.88 ? 411 SER B C 1 ATOM 6603 O O . SER C 1 359 ? 22.043 112.752 10.842 1.00 18.53 ? 411 SER B O 1 ATOM 6604 C CB . SER C 1 359 ? 20.863 110.746 8.871 1.00 20.00 ? 411 SER B CB 1 ATOM 6605 O OG . SER C 1 359 ? 21.811 109.693 8.947 1.00 22.69 ? 411 SER B OG 1 ATOM 6606 N N . LYS C 1 360 ? 21.896 110.903 12.124 1.00 19.67 ? 412 LYS B N 1 ATOM 6607 C CA . LYS C 1 360 ? 23.017 111.239 12.997 1.00 22.11 ? 412 LYS B CA 1 ATOM 6608 C C . LYS C 1 360 ? 22.894 112.643 13.568 1.00 21.25 ? 412 LYS B C 1 ATOM 6609 O O . LYS C 1 360 ? 23.877 113.386 13.637 1.00 23.01 ? 412 LYS B O 1 ATOM 6610 C CB . LYS C 1 360 ? 24.340 111.106 12.249 1.00 23.15 ? 412 LYS B CB 1 ATOM 6611 C CG . LYS C 1 360 ? 24.555 109.749 11.604 1.00 29.57 ? 412 LYS B CG 1 ATOM 6612 C CD . LYS C 1 360 ? 25.974 109.618 11.071 1.00 35.34 ? 412 LYS B CD 1 ATOM 6613 C CE . LYS C 1 360 ? 26.055 108.657 9.900 1.00 43.89 ? 412 LYS B CE 1 ATOM 6614 N NZ . LYS C 1 360 ? 25.233 107.433 10.104 1.00 49.44 ? 412 LYS B NZ 1 ATOM 6615 N N . GLY C 1 361 ? 21.678 113.002 13.963 1.00 20.26 ? 413 GLY B N 1 ATOM 6616 C CA . GLY C 1 361 ? 21.440 114.210 14.733 1.00 21.12 ? 413 GLY B CA 1 ATOM 6617 C C . GLY C 1 361 ? 21.396 115.512 13.954 1.00 20.67 ? 413 GLY B C 1 ATOM 6618 O O . GLY C 1 361 ? 20.486 116.319 14.152 1.00 27.36 ? 413 GLY B O 1 ATOM 6619 N N . LYS C 1 362 ? 22.374 115.708 13.074 1.00 20.55 ? 414 LYS B N 1 ATOM 6620 C CA . LYS C 1 362 ? 22.603 117.001 12.433 1.00 25.47 ? 414 LYS B CA 1 ATOM 6621 C C . LYS C 1 362 ? 22.502 116.956 10.916 1.00 23.82 ? 414 LYS B C 1 ATOM 6622 O O . LYS C 1 362 ? 22.738 117.960 10.248 1.00 21.45 ? 414 LYS B O 1 ATOM 6623 C CB . LYS C 1 362 ? 23.992 117.527 12.801 1.00 30.06 ? 414 LYS B CB 1 ATOM 6624 C CG . LYS C 1 362 ? 24.154 117.974 14.236 1.00 47.58 ? 414 LYS B CG 1 ATOM 6625 C CD . LYS C 1 362 ? 25.543 118.572 14.472 1.00 42.15 ? 414 LYS B CD 1 ATOM 6626 C CE . LYS C 1 362 ? 26.656 117.548 14.268 1.00 46.82 ? 414 LYS B CE 1 ATOM 6627 N NZ . LYS C 1 362 ? 27.143 117.461 12.856 1.00 48.29 ? 414 LYS B NZ 1 ATOM 6628 N N . TYR C 1 363 ? 22.178 115.791 10.371 1.00 17.95 ? 415 TYR B N 1 ATOM 6629 C CA . TYR C 1 363 ? 22.145 115.615 8.928 1.00 16.20 ? 415 TYR B CA 1 ATOM 6630 C C . TYR C 1 363 ? 20.764 115.138 8.512 1.00 16.17 ? 415 TYR B C 1 ATOM 6631 O O . TYR C 1 363 ? 19.934 114.791 9.353 1.00 15.62 ? 415 TYR B O 1 ATOM 6632 C CB . TYR C 1 363 ? 23.232 114.632 8.480 1.00 21.27 ? 415 TYR B CB 1 ATOM 6633 C CG . TYR C 1 363 ? 24.625 115.123 8.818 1.00 24.57 ? 415 TYR B CG 1 ATOM 6634 C CD1 . TYR C 1 363 ? 25.305 115.973 7.958 1.00 26.96 ? 415 TYR B CD1 1 ATOM 6635 C CD2 . TYR C 1 363 ? 25.242 114.761 10.009 1.00 29.81 ? 415 TYR B CD2 1 ATOM 6636 C CE1 . TYR C 1 363 ? 26.569 116.442 8.266 1.00 34.64 ? 415 TYR B CE1 1 ATOM 6637 C CE2 . TYR C 1 363 ? 26.511 115.226 10.327 1.00 32.01 ? 415 TYR B CE2 1 ATOM 6638 C CZ . TYR C 1 363 ? 27.166 116.066 9.450 1.00 37.55 ? 415 TYR B CZ 1 ATOM 6639 O OH . TYR C 1 363 ? 28.426 116.534 9.756 1.00 40.44 ? 415 TYR B OH 1 ATOM 6640 N N . CYS C 1 364 ? 20.521 115.158 7.209 1.00 19.18 ? 416 CYS B N 1 ATOM 6641 C CA . CYS C 1 364 ? 19.251 114.705 6.656 1.00 16.85 ? 416 CYS B CA 1 ATOM 6642 C C . CYS C 1 364 ? 19.554 113.668 5.583 1.00 17.64 ? 416 CYS B C 1 ATOM 6643 O O . CYS C 1 364 ? 20.530 113.800 4.847 1.00 18.78 ? 416 CYS B O 1 ATOM 6644 C CB . CYS C 1 364 ? 18.464 115.891 6.092 1.00 15.59 ? 416 CYS B CB 1 ATOM 6645 S SG . CYS C 1 364 ? 16.724 115.559 5.705 1.00 19.09 ? 416 CYS B SG 1 ATOM 6646 N N . LYS C 1 365 ? 18.755 112.608 5.528 1.00 15.03 ? 417 LYS B N 1 ATOM 6647 C CA . LYS C 1 365 ? 18.862 111.647 4.441 1.00 15.59 ? 417 LYS B CA 1 ATOM 6648 C C . LYS C 1 365 ? 17.499 111.507 3.780 1.00 13.46 ? 417 LYS B C 1 ATOM 6649 O O . LYS C 1 365 ? 16.468 111.625 4.446 1.00 14.13 ? 417 LYS B O 1 ATOM 6650 C CB . LYS C 1 365 ? 19.370 110.295 4.938 1.00 16.87 ? 417 LYS B CB 1 ATOM 6651 C CG . LYS C 1 365 ? 18.495 109.658 5.977 1.00 17.79 ? 417 LYS B CG 1 ATOM 6652 C CD . LYS C 1 365 ? 19.055 108.312 6.415 1.00 20.48 ? 417 LYS B CD 1 ATOM 6653 C CE . LYS C 1 365 ? 18.156 107.661 7.442 1.00 22.31 ? 417 LYS B CE 1 ATOM 6654 N NZ . LYS C 1 365 ? 18.724 106.369 7.913 1.00 32.45 ? 417 LYS B NZ 1 ATOM 6655 N N . PRO C 1 366 ? 17.490 111.265 2.465 1.00 15.47 ? 418 PRO B N 1 ATOM 6656 C CA . PRO C 1 366 ? 16.206 111.152 1.775 1.00 15.38 ? 418 PRO B CA 1 ATOM 6657 C C . PRO C 1 366 ? 15.358 110.021 2.341 1.00 17.49 ? 418 PRO B C 1 ATOM 6658 O O . PRO C 1 366 ? 15.888 108.994 2.787 1.00 16.68 ? 418 PRO B O 1 ATOM 6659 C CB . PRO C 1 366 ? 16.603 110.882 0.319 1.00 17.07 ? 418 PRO B CB 1 ATOM 6660 C CG . PRO C 1 366 ? 18.008 110.402 0.372 1.00 24.07 ? 418 PRO B CG 1 ATOM 6661 C CD . PRO C 1 366 ? 18.631 111.044 1.564 1.00 15.66 ? 418 PRO B CD 1 ATOM 6662 N N . MET C 1 367 ? 14.048 110.224 2.355 1.00 15.07 ? 419 MET B N 1 ATOM 6663 C CA . MET C 1 367 ? 13.132 109.185 2.784 1.00 15.71 ? 419 MET B CA 1 ATOM 6664 C C . MET C 1 367 ? 13.238 108.027 1.792 1.00 15.19 ? 419 MET B C 1 ATOM 6665 O O . MET C 1 367 ? 13.764 108.188 0.691 1.00 16.49 ? 419 MET B O 1 ATOM 6666 C CB . MET C 1 367 ? 11.703 109.735 2.872 1.00 15.69 ? 419 MET B CB 1 ATOM 6667 C CG . MET C 1 367 ? 11.582 110.961 3.800 1.00 16.36 ? 419 MET B CG 1 ATOM 6668 S SD . MET C 1 367 ? 9.963 111.177 4.561 1.00 19.57 ? 419 MET B SD 1 ATOM 6669 C CE . MET C 1 367 ? 8.967 111.535 3.124 1.00 16.47 ? 419 MET B CE 1 ATOM 6670 N N . ASN C 1 368 ? 12.772 106.851 2.193 1.00 17.13 ? 420 ASN B N 1 ATOM 6671 C CA . ASN C 1 368 ? 12.796 105.693 1.308 1.00 18.31 ? 420 ASN B CA 1 ATOM 6672 C C . ASN C 1 368 ? 11.548 105.649 0.450 1.00 13.20 ? 420 ASN B C 1 ATOM 6673 O O . ASN C 1 368 ? 10.437 105.555 0.971 1.00 13.80 ? 420 ASN B O 1 ATOM 6674 C CB . ASN C 1 368 ? 12.920 104.401 2.110 1.00 19.62 ? 420 ASN B CB 1 ATOM 6675 C CG . ASN C 1 368 ? 14.219 104.320 2.877 1.00 24.43 ? 420 ASN B CG 1 ATOM 6676 O OD1 . ASN C 1 368 ? 14.228 104.035 4.073 1.00 36.31 ? 420 ASN B OD1 1 ATOM 6677 N ND2 . ASN C 1 368 ? 15.322 104.587 2.197 1.00 26.42 ? 420 ASN B ND2 1 ATOM 6678 N N . ALA C 1 369 ? 11.733 105.719 -0.862 1.00 13.43 ? 421 ALA B N 1 ATOM 6679 C CA . ALA C 1 369 ? 10.603 105.744 -1.781 1.00 13.31 ? 421 ALA B CA 1 ATOM 6680 C C . ALA C 1 369 ? 9.772 104.474 -1.679 1.00 14.06 ? 421 ALA B C 1 ATOM 6681 O O . ALA C 1 369 ? 10.315 103.371 -1.584 1.00 15.96 ? 421 ALA B O 1 ATOM 6682 C CB . ALA C 1 369 ? 11.085 105.933 -3.203 1.00 18.46 ? 421 ALA B CB 1 ATOM 6683 N N . ARG C 1 370 ? 8.454 104.641 -1.693 1.00 11.96 ? 422 ARG B N 1 ATOM 6684 C CA . ARG C 1 370 ? 7.539 103.513 -1.845 1.00 11.05 ? 422 ARG B CA 1 ATOM 6685 C C . ARG C 1 370 ? 7.387 103.145 -3.306 1.00 12.01 ? 422 ARG B C 1 ATOM 6686 O O . ARG C 1 370 ? 7.131 101.980 -3.645 1.00 12.44 ? 422 ARG B O 1 ATOM 6687 C CB . ARG C 1 370 ? 6.164 103.842 -1.263 1.00 13.48 ? 422 ARG B CB 1 ATOM 6688 C CG . ARG C 1 370 ? 6.140 104.122 0.234 1.00 15.93 ? 422 ARG B CG 1 ATOM 6689 C CD . ARG C 1 370 ? 6.363 102.877 1.076 1.00 25.74 ? 422 ARG B CD 1 ATOM 6690 N NE . ARG C 1 370 ? 5.464 101.783 0.703 1.00 28.49 ? 422 ARG B NE 1 ATOM 6691 C CZ . ARG C 1 370 ? 4.195 101.677 1.090 1.00 31.71 ? 422 ARG B CZ 1 ATOM 6692 N NH1 . ARG C 1 370 ? 3.646 102.602 1.866 1.00 27.33 ? 422 ARG B NH1 1 ATOM 6693 N NH2 . ARG C 1 370 ? 3.462 100.642 0.695 1.00 36.88 ? 422 ARG B NH2 1 ATOM 6694 N N . ALA C 1 371 ? 7.515 104.142 -4.170 1.00 11.60 ? 423 ALA B N 1 ATOM 6695 C CA . ALA C 1 371 ? 7.200 104.012 -5.579 1.00 11.91 ? 423 ALA B CA 1 ATOM 6696 C C . ALA C 1 371 ? 7.804 105.167 -6.340 1.00 13.73 ? 423 ALA B C 1 ATOM 6697 O O . ALA C 1 371 ? 8.156 106.192 -5.747 1.00 12.31 ? 423 ALA B O 1 ATOM 6698 C CB . ALA C 1 371 ? 5.678 103.972 -5.790 1.00 14.22 ? 423 ALA B CB 1 ATOM 6699 N N . SER C 1 372 ? 7.931 105.013 -7.652 1.00 12.12 ? 424 SER B N 1 ATOM 6700 C CA . SER C 1 372 ? 8.391 106.107 -8.483 1.00 13.03 ? 424 SER B CA 1 ATOM 6701 C C . SER C 1 372 ? 7.672 106.110 -9.814 1.00 13.05 ? 424 SER B C 1 ATOM 6702 O O . SER C 1 372 ? 7.122 105.094 -10.240 1.00 13.47 ? 424 SER B O 1 ATOM 6703 C CB . SER C 1 372 ? 9.902 106.040 -8.707 1.00 14.34 ? 424 SER B CB 1 ATOM 6704 O OG . SER C 1 372 ? 10.250 104.993 -9.604 1.00 15.81 ? 424 SER B OG 1 ATOM 6705 N N . LEU C 1 373 ? 7.676 107.275 -10.453 1.00 12.44 ? 425 LEU B N 1 ATOM 6706 C CA . LEU C 1 373 ? 7.111 107.468 -11.774 1.00 11.94 ? 425 LEU B CA 1 ATOM 6707 C C . LEU C 1 373 ? 8.180 108.144 -12.628 1.00 18.09 ? 425 LEU B C 1 ATOM 6708 O O . LEU C 1 373 ? 8.728 109.167 -12.222 1.00 16.70 ? 425 LEU B O 1 ATOM 6709 C CB . LEU C 1 373 ? 5.838 108.312 -11.681 1.00 15.93 ? 425 LEU B CB 1 ATOM 6710 C CG . LEU C 1 373 ? 4.979 108.579 -12.906 1.00 23.40 ? 425 LEU B CG 1 ATOM 6711 C CD1 . LEU C 1 373 ? 4.362 107.295 -13.423 1.00 25.47 ? 425 LEU B CD1 1 ATOM 6712 C CD2 . LEU C 1 373 ? 3.895 109.586 -12.546 1.00 25.17 ? 425 LEU B CD2 1 ATOM 6713 N N . SER C 1 374 ? 8.502 107.569 -13.785 1.00 13.96 ? 426 SER B N 1 ATOM 6714 C CA . SER C 1 374 ? 9.557 108.115 -14.637 1.00 13.61 ? 426 SER B CA 1 ATOM 6715 C C . SER C 1 374 ? 9.016 109.014 -15.748 1.00 13.74 ? 426 SER B C 1 ATOM 6716 O O . SER C 1 374 ? 7.884 108.861 -16.206 1.00 15.70 ? 426 SER B O 1 ATOM 6717 C CB . SER C 1 374 ? 10.388 106.979 -15.247 1.00 16.20 ? 426 SER B CB 1 ATOM 6718 O OG . SER C 1 374 ? 11.119 106.292 -14.254 1.00 16.96 ? 426 SER B OG 1 ATOM 6719 N N . ASN C 1 375 ? 9.853 109.963 -16.168 1.00 17.47 ? 427 ASN B N 1 ATOM 6720 C CA . ASN C 1 375 ? 9.566 110.870 -17.281 1.00 18.88 ? 427 ASN B CA 1 ATOM 6721 C C . ASN C 1 375 ? 8.259 111.636 -17.125 1.00 16.13 ? 427 ASN B C 1 ATOM 6722 O O . ASN C 1 375 ? 7.473 111.748 -18.062 1.00 19.89 ? 427 ASN B O 1 ATOM 6723 C CB . ASN C 1 375 ? 9.549 110.082 -18.581 1.00 20.65 ? 427 ASN B CB 1 ATOM 6724 C CG . ASN C 1 375 ? 9.712 110.950 -19.803 1.00 28.58 ? 427 ASN B CG 1 ATOM 6725 O OD1 . ASN C 1 375 ? 10.289 112.041 -19.760 1.00 25.11 ? 427 ASN B OD1 1 ATOM 6726 N ND2 . ASN C 1 375 ? 9.207 110.452 -20.913 1.00 33.95 ? 427 ASN B ND2 1 ATOM 6727 N N . ALA C 1 376 ? 8.050 112.171 -15.927 1.00 15.22 ? 428 ALA B N 1 ATOM 6728 C CA . ALA C 1 376 ? 6.874 112.961 -15.608 1.00 14.52 ? 428 ALA B CA 1 ATOM 6729 C C . ALA C 1 376 ? 7.262 114.429 -15.524 1.00 14.77 ? 428 ALA B C 1 ATOM 6730 O O . ALA C 1 376 ? 8.435 114.746 -15.385 1.00 15.30 ? 428 ALA B O 1 ATOM 6731 C CB . ALA C 1 376 ? 6.279 112.498 -14.308 1.00 17.24 ? 428 ALA B CB 1 ATOM 6732 N N . THR C 1 377 ? 6.273 115.307 -15.622 1.00 14.33 ? 429 THR B N 1 ATOM 6733 C CA . THR C 1 377 ? 6.474 116.712 -15.289 1.00 13.75 ? 429 THR B CA 1 ATOM 6734 C C . THR C 1 377 ? 6.245 116.913 -13.800 1.00 14.42 ? 429 THR B C 1 ATOM 6735 O O . THR C 1 377 ? 5.657 116.061 -13.135 1.00 13.58 ? 429 THR B O 1 ATOM 6736 C CB . THR C 1 377 ? 5.527 117.625 -16.055 1.00 14.76 ? 429 THR B CB 1 ATOM 6737 O OG1 . THR C 1 377 ? 4.179 117.367 -15.647 1.00 15.88 ? 429 THR B OG1 1 ATOM 6738 C CG2 . THR C 1 377 ? 5.671 117.409 -17.572 1.00 16.99 ? 429 THR B CG2 1 ATOM 6739 N N . ALA C 1 378 ? 6.696 118.045 -13.268 1.00 13.93 ? 430 ALA B N 1 ATOM 6740 C CA . ALA C 1 378 ? 6.468 118.343 -11.859 1.00 14.03 ? 430 ALA B CA 1 ATOM 6741 C C . ALA C 1 378 ? 4.972 118.438 -11.534 1.00 12.39 ? 430 ALA B C 1 ATOM 6742 O O . ALA C 1 378 ? 4.524 117.931 -10.501 1.00 12.42 ? 430 ALA B O 1 ATOM 6743 C CB . ALA C 1 378 ? 7.188 119.630 -11.468 1.00 13.54 ? 430 ALA B CB 1 ATOM 6744 N N . GLU C 1 379 ? 4.194 119.060 -12.413 1.00 12.18 ? 431 GLU B N 1 ATOM 6745 C CA . GLU C 1 379 ? 2.747 119.142 -12.232 1.00 12.37 ? 431 GLU B CA 1 ATOM 6746 C C . GLU C 1 379 ? 2.140 117.748 -12.162 1.00 13.60 ? 431 GLU B C 1 ATOM 6747 O O . GLU C 1 379 ? 1.296 117.479 -11.311 1.00 13.45 ? 431 GLU B O 1 ATOM 6748 C CB . GLU C 1 379 ? 2.106 119.949 -13.366 1.00 13.71 ? 431 GLU B CB 1 ATOM 6749 C CG . GLU C 1 379 ? 0.587 120.037 -13.280 1.00 14.63 ? 431 GLU B CG 1 ATOM 6750 C CD . GLU C 1 379 ? -0.037 120.873 -14.394 1.00 20.27 ? 431 GLU B CD 1 ATOM 6751 O OE1 . GLU C 1 379 ? 0.701 121.333 -15.294 1.00 26.70 ? 431 GLU B OE1 1 ATOM 6752 O OE2 . GLU C 1 379 ? -1.272 121.071 -14.372 1.00 17.25 ? 431 GLU B OE2 1 ATOM 6753 N N . GLN C 1 380 ? 2.571 116.865 -13.055 1.00 12.17 ? 432 GLN B N 1 ATOM 6754 C CA . GLN C 1 380 ? 2.083 115.488 -13.040 1.00 13.74 ? 432 GLN B CA 1 ATOM 6755 C C . GLN C 1 380 ? 2.437 114.785 -11.730 1.00 13.30 ? 432 GLN B C 1 ATOM 6756 O O . GLN C 1 380 ? 1.632 114.013 -11.202 1.00 13.76 ? 432 GLN B O 1 ATOM 6757 C CB . GLN C 1 380 ? 2.646 114.710 -14.226 1.00 16.44 ? 432 GLN B CB 1 ATOM 6758 C CG . GLN C 1 380 ? 2.008 115.087 -15.537 1.00 18.25 ? 432 GLN B CG 1 ATOM 6759 C CD . GLN C 1 380 ? 2.673 114.411 -16.723 1.00 20.00 ? 432 GLN B CD 1 ATOM 6760 O OE1 . GLN C 1 380 ? 3.794 113.911 -16.623 1.00 18.53 ? 432 GLN B OE1 1 ATOM 6761 N NE2 . GLN C 1 380 ? 1.978 114.386 -17.853 1.00 32.65 ? 432 GLN B NE2 1 ATOM 6762 N N . CYS C 1 381 ? 3.633 115.047 -11.207 1.00 14.55 ? 433 CYS B N 1 ATOM 6763 C CA . CYS C 1 381 ? 4.048 114.497 -9.924 1.00 14.50 ? 433 CYS B CA 1 ATOM 6764 C C . CYS C 1 381 ? 3.060 114.870 -8.819 1.00 14.43 ? 433 CYS B C 1 ATOM 6765 O O . CYS C 1 381 ? 2.584 114.017 -8.053 1.00 13.19 ? 433 CYS B O 1 ATOM 6766 C CB . CYS C 1 381 ? 5.442 115.013 -9.569 1.00 14.85 ? 433 CYS B CB 1 ATOM 6767 S SG . CYS C 1 381 ? 6.196 114.306 -8.104 1.00 19.77 ? 433 CYS B SG 1 ATOM 6768 N N . GLY C 1 382 ? 2.745 116.158 -8.733 1.00 12.37 ? 434 GLY B N 1 ATOM 6769 C CA . GLY C 1 382 ? 1.814 116.625 -7.731 1.00 11.86 ? 434 GLY B CA 1 ATOM 6770 C C . GLY C 1 382 ? 0.417 116.074 -7.939 1.00 12.44 ? 434 GLY B C 1 ATOM 6771 O O . GLY C 1 382 ? -0.259 115.727 -6.973 1.00 12.31 ? 434 GLY B O 1 ATOM 6772 N N . GLN C 1 383 ? -0.014 116.005 -9.195 1.00 12.38 ? 435 GLN B N 1 ATOM 6773 C CA . GLN C 1 383 ? -1.323 115.458 -9.529 1.00 11.00 ? 435 GLN B CA 1 ATOM 6774 C C . GLN C 1 383 ? -1.438 113.995 -9.139 1.00 12.04 ? 435 GLN B C 1 ATOM 6775 O O . GLN C 1 383 ? -2.403 113.591 -8.488 1.00 12.85 ? 435 GLN B O 1 ATOM 6776 C CB . GLN C 1 383 ? -1.599 115.605 -11.021 1.00 13.51 ? 435 GLN B CB 1 ATOM 6777 C CG . GLN C 1 383 ? -1.866 117.025 -11.454 1.00 12.73 ? 435 GLN B CG 1 ATOM 6778 C CD . GLN C 1 383 ? -1.961 117.177 -12.958 1.00 15.52 ? 435 GLN B CD 1 ATOM 6779 O OE1 . GLN C 1 383 ? -1.173 116.603 -13.707 1.00 17.81 ? 435 GLN B OE1 1 ATOM 6780 N NE2 . GLN C 1 383 ? -2.929 117.953 -13.408 1.00 16.15 ? 435 GLN B NE2 1 ATOM 6781 N N . ARG C 1 384 ? -0.463 113.190 -9.535 1.00 12.33 ? 436 ARG B N 1 ATOM 6782 C CA . ARG C 1 384 ? -0.545 111.778 -9.199 1.00 11.97 ? 436 ARG B CA 1 ATOM 6783 C C . ARG C 1 384 ? -0.395 111.542 -7.700 1.00 11.92 ? 436 ARG B C 1 ATOM 6784 O O . ARG C 1 384 ? -1.064 110.671 -7.160 1.00 12.04 ? 436 ARG B O 1 ATOM 6785 C CB . ARG C 1 384 ? 0.480 110.965 -9.981 1.00 16.04 ? 436 ARG B CB 1 ATOM 6786 C CG . ARG C 1 384 ? 0.107 110.758 -11.453 1.00 21.19 ? 436 ARG B CG 1 ATOM 6787 C CD . ARG C 1 384 ? -1.310 110.159 -11.673 1.00 20.08 ? 436 ARG B CD 1 ATOM 6788 N NE . ARG C 1 384 ? -1.420 108.755 -11.282 1.00 20.85 ? 436 ARG B NE 1 ATOM 6789 C CZ . ARG C 1 384 ? -2.537 108.036 -11.405 1.00 20.47 ? 436 ARG B CZ 1 ATOM 6790 N NH1 . ARG C 1 384 ? -2.564 106.763 -11.040 1.00 19.99 ? 436 ARG B NH1 1 ATOM 6791 N NH2 . ARG C 1 384 ? -3.637 108.592 -11.894 1.00 19.29 ? 436 ARG B NH2 1 ATOM 6792 N N . LEU C 1 385 ? 0.436 112.325 -7.010 1.00 10.90 ? 437 LEU B N 1 ATOM 6793 C CA . LEU C 1 385 ? 0.499 112.229 -5.553 1.00 10.67 ? 437 LEU B CA 1 ATOM 6794 C C . LEU C 1 385 ? -0.889 112.401 -4.921 1.00 11.29 ? 437 LEU B C 1 ATOM 6795 O O . LEU C 1 385 ? -1.309 111.614 -4.073 1.00 11.65 ? 437 LEU B O 1 ATOM 6796 C CB . LEU C 1 385 ? 1.467 113.277 -4.997 1.00 11.66 ? 437 LEU B CB 1 ATOM 6797 C CG . LEU C 1 385 ? 1.583 113.368 -3.476 1.00 10.28 ? 437 LEU B CG 1 ATOM 6798 C CD1 . LEU C 1 385 ? 2.111 112.081 -2.880 1.00 12.37 ? 437 LEU B CD1 1 ATOM 6799 C CD2 . LEU C 1 385 ? 2.472 114.547 -3.090 1.00 12.51 ? 437 LEU B CD2 1 ATOM 6800 N N . PHE C 1 386 ? -1.602 113.430 -5.355 1.00 10.78 ? 438 PHE B N 1 ATOM 6801 C CA . PHE C 1 386 ? -2.947 113.700 -4.877 1.00 9.64 ? 438 PHE B CA 1 ATOM 6802 C C . PHE C 1 386 ? -3.868 112.493 -5.131 1.00 10.27 ? 438 PHE B C 1 ATOM 6803 O O . PHE C 1 386 ? -4.592 112.048 -4.239 1.00 12.68 ? 438 PHE B O 1 ATOM 6804 C CB . PHE C 1 386 ? -3.450 114.974 -5.575 1.00 9.94 ? 438 PHE B CB 1 ATOM 6805 C CG . PHE C 1 386 ? -4.877 115.351 -5.272 1.00 10.04 ? 438 PHE B CG 1 ATOM 6806 C CD1 . PHE C 1 386 ? -5.331 115.483 -3.963 1.00 11.21 ? 438 PHE B CD1 1 ATOM 6807 C CD2 . PHE C 1 386 ? -5.759 115.626 -6.309 1.00 9.66 ? 438 PHE B CD2 1 ATOM 6808 C CE1 . PHE C 1 386 ? -6.636 115.863 -3.692 1.00 11.38 ? 438 PHE B CE1 1 ATOM 6809 C CE2 . PHE C 1 386 ? -7.062 116.002 -6.043 1.00 9.96 ? 438 PHE B CE2 1 ATOM 6810 C CZ . PHE C 1 386 ? -7.504 116.122 -4.729 1.00 10.33 ? 438 PHE B CZ 1 ATOM 6811 N N . MET C 1 387 ? -3.798 111.949 -6.341 1.00 11.49 ? 439 MET B N 1 ATOM 6812 C CA . MET C 1 387 ? -4.657 110.823 -6.742 1.00 11.78 ? 439 MET B CA 1 ATOM 6813 C C . MET C 1 387 ? -4.262 109.494 -6.085 1.00 13.89 ? 439 MET B C 1 ATOM 6814 O O . MET C 1 387 ? -5.068 108.558 -6.046 1.00 13.50 ? 439 MET B O 1 ATOM 6815 C CB . MET C 1 387 ? -4.630 110.682 -8.268 1.00 13.31 ? 439 MET B CB 1 ATOM 6816 C CG . MET C 1 387 ? -5.129 111.929 -8.987 1.00 14.44 ? 439 MET B CG 1 ATOM 6817 S SD . MET C 1 387 ? -4.774 111.910 -10.753 1.00 20.27 ? 439 MET B SD 1 ATOM 6818 C CE . MET C 1 387 ? -6.060 110.800 -11.306 1.00 17.31 ? 439 MET B CE 1 ATOM 6819 N N . LEU C 1 388 ? -3.049 109.431 -5.543 1.00 11.17 ? 440 LEU B N 1 ATOM 6820 C CA . LEU C 1 388 ? -2.531 108.229 -4.894 1.00 12.58 ? 440 LEU B CA 1 ATOM 6821 C C . LEU C 1 388 ? -2.444 108.367 -3.373 1.00 11.29 ? 440 LEU B C 1 ATOM 6822 O O . LEU C 1 388 ? -1.794 107.557 -2.707 1.00 11.13 ? 440 LEU B O 1 ATOM 6823 C CB . LEU C 1 388 ? -1.153 107.890 -5.457 1.00 11.27 ? 440 LEU B CB 1 ATOM 6824 C CG . LEU C 1 388 ? -1.078 107.543 -6.946 1.00 13.22 ? 440 LEU B CG 1 ATOM 6825 C CD1 . LEU C 1 388 ? 0.366 107.352 -7.360 1.00 14.78 ? 440 LEU B CD1 1 ATOM 6826 C CD2 . LEU C 1 388 ? -1.893 106.292 -7.242 1.00 15.56 ? 440 LEU B CD2 1 ATOM 6827 N N . SER C 1 389 ? -3.111 109.378 -2.817 1.00 10.90 ? 441 SER B N 1 ATOM 6828 C CA . SER C 1 389 ? -2.925 109.710 -1.408 1.00 10.09 ? 441 SER B CA 1 ATOM 6829 C C . SER C 1 389 ? -3.857 108.904 -0.506 1.00 11.38 ? 441 SER B C 1 ATOM 6830 O O . SER C 1 389 ? -3.478 107.830 -0.038 1.00 11.65 ? 441 SER B O 1 ATOM 6831 C CB . SER C 1 389 ? -3.090 111.229 -1.193 1.00 9.96 ? 441 SER B CB 1 ATOM 6832 O OG . SER C 1 389 ? -4.370 111.704 -1.574 1.00 11.04 ? 441 SER B OG 1 ATOM 6833 N N . SER C 1 390 ? -5.065 109.387 -0.263 1.00 9.14 ? 442 SER B N 1 ATOM 6834 C CA . SER C 1 390 ? -5.995 108.655 0.586 1.00 11.16 ? 442 SER B CA 1 ATOM 6835 C C . SER C 1 390 ? -7.417 109.043 0.224 1.00 11.26 ? 442 SER B C 1 ATOM 6836 O O . SER C 1 390 ? -7.668 110.126 -0.318 1.00 9.78 ? 442 SER B O 1 ATOM 6837 C CB . SER C 1 390 ? -5.707 108.912 2.068 1.00 11.03 ? 442 SER B CB 1 ATOM 6838 O OG . SER C 1 390 ? -5.766 110.300 2.366 1.00 11.46 ? 442 SER B OG 1 ATOM 6839 N N . ALA C 1 391 ? -8.350 108.141 0.491 1.00 10.44 ? 443 ALA B N 1 ATOM 6840 C CA . ALA C 1 391 ? -9.731 108.368 0.103 1.00 9.14 ? 443 ALA B CA 1 ATOM 6841 C C . ALA C 1 391 ? -10.657 107.573 0.992 1.00 13.36 ? 443 ALA B C 1 ATOM 6842 O O . ALA C 1 391 ? -10.441 106.382 1.235 1.00 14.59 ? 443 ALA B O 1 ATOM 6843 C CB . ALA C 1 391 ? -9.955 107.994 -1.356 1.00 10.75 ? 443 ALA B CB 1 ATOM 6844 N N . ASP C 1 392 ? -11.689 108.239 1.480 1.00 10.42 ? 444 ASP B N 1 ATOM 6845 C CA . ASP C 1 392 ? -12.763 107.572 2.184 1.00 10.71 ? 444 ASP B CA 1 ATOM 6846 C C . ASP C 1 392 ? -13.809 107.130 1.152 1.00 12.14 ? 444 ASP B C 1 ATOM 6847 O O . ASP C 1 392 ? -13.687 107.438 -0.035 1.00 14.95 ? 444 ASP B O 1 ATOM 6848 C CB . ASP C 1 392 ? -13.332 108.511 3.248 1.00 13.07 ? 444 ASP B CB 1 ATOM 6849 C CG . ASP C 1 392 ? -12.271 108.930 4.264 1.00 13.71 ? 444 ASP B CG 1 ATOM 6850 O OD1 . ASP C 1 392 ? -11.519 108.043 4.739 1.00 15.52 ? 444 ASP B OD1 1 ATOM 6851 O OD2 . ASP C 1 392 ? -12.154 110.139 4.575 1.00 12.26 ? 444 ASP B OD2 1 ATOM 6852 N N . GLY C 1 393 ? -14.819 106.393 1.595 1.00 11.87 ? 445 GLY B N 1 ATOM 6853 C CA . GLY C 1 393 ? -15.856 105.907 0.693 1.00 13.80 ? 445 GLY B CA 1 ATOM 6854 C C . GLY C 1 393 ? -15.588 104.559 0.022 1.00 15.49 ? 445 GLY B C 1 ATOM 6855 O O . GLY C 1 393 ? -16.332 104.161 -0.876 1.00 15.96 ? 445 GLY B O 1 ATOM 6856 N N . SER C 1 394 ? -14.521 103.886 0.449 1.00 13.60 ? 446 SER B N 1 ATOM 6857 C CA . SER C 1 394 ? -14.201 102.483 0.091 1.00 12.96 ? 446 SER B CA 1 ATOM 6858 C C . SER C 1 394 ? -13.703 102.230 -1.340 1.00 11.76 ? 446 SER B C 1 ATOM 6859 O O . SER C 1 394 ? -12.650 101.623 -1.530 1.00 12.34 ? 446 SER B O 1 ATOM 6860 C CB . SER C 1 394 ? -15.418 101.577 0.330 1.00 17.18 ? 446 SER B CB 1 ATOM 6861 O OG . SER C 1 394 ? -15.719 101.470 1.713 1.00 20.00 ? 446 SER B OG 1 ATOM 6862 N N . SER C 1 395 ? -14.457 102.695 -2.329 1.00 12.09 ? 447 SER B N 1 ATOM 6863 C CA . SER C 1 395 ? -14.294 102.274 -3.716 1.00 13.64 ? 447 SER B CA 1 ATOM 6864 C C . SER C 1 395 ? -12.930 102.556 -4.332 1.00 11.70 ? 447 SER B C 1 ATOM 6865 O O . SER C 1 395 ? -12.474 101.809 -5.196 1.00 13.12 ? 447 SER B O 1 ATOM 6866 C CB . SER C 1 395 ? -15.376 102.945 -4.570 1.00 19.31 ? 447 SER B CB 1 ATOM 6867 O OG . SER C 1 395 ? -16.659 102.477 -4.201 1.00 30.00 ? 447 SER B OG 1 ATOM 6868 N N . LEU C 1 396 ? -12.277 103.627 -3.892 1.00 11.73 ? 448 LEU B N 1 ATOM 6869 C CA . LEU C 1 396 ? -11.006 104.021 -4.467 1.00 13.25 ? 448 LEU B CA 1 ATOM 6870 C C . LEU C 1 396 ? -9.798 103.435 -3.723 1.00 13.62 ? 448 LEU B C 1 ATOM 6871 O O . LEU C 1 396 ? -8.660 103.807 -4.023 1.00 11.51 ? 448 LEU B O 1 ATOM 6872 C CB . LEU C 1 396 ? -10.909 105.552 -4.499 1.00 13.13 ? 448 LEU B CB 1 ATOM 6873 C CG . LEU C 1 396 ? -11.845 106.254 -5.487 1.00 12.75 ? 448 LEU B CG 1 ATOM 6874 C CD1 . LEU C 1 396 ? -11.835 107.768 -5.272 1.00 16.27 ? 448 LEU B CD1 1 ATOM 6875 C CD2 . LEU C 1 396 ? -11.448 105.927 -6.925 1.00 18.96 ? 448 LEU B CD2 1 ATOM 6876 N N . SER C 1 397 ? -10.021 102.508 -2.784 1.00 10.45 ? 449 SER B N 1 ATOM 6877 C CA . SER C 1 397 ? -8.920 101.979 -1.964 1.00 12.66 ? 449 SER B CA 1 ATOM 6878 C C . SER C 1 397 ? -7.840 101.261 -2.795 1.00 11.94 ? 449 SER B C 1 ATOM 6879 O O . SER C 1 397 ? -6.676 101.197 -2.386 1.00 12.93 ? 449 SER B O 1 ATOM 6880 C CB . SER C 1 397 ? -9.465 101.025 -0.896 1.00 13.45 ? 449 SER B CB 1 ATOM 6881 O OG . SER C 1 397 ? -9.957 99.850 -1.500 1.00 15.70 ? 449 SER B OG 1 ATOM 6882 N N . SER C 1 398 ? -8.216 100.721 -3.952 1.00 11.62 ? 450 SER B N 1 ATOM 6883 C CA . SER C 1 398 ? -7.268 100.013 -4.816 1.00 10.73 ? 450 SER B CA 1 ATOM 6884 C C . SER C 1 398 ? -6.367 100.983 -5.584 1.00 13.10 ? 450 SER B C 1 ATOM 6885 O O . SER C 1 398 ? -5.335 100.589 -6.121 1.00 12.62 ? 450 SER B O 1 ATOM 6886 C CB . SER C 1 398 ? -8.023 99.108 -5.795 1.00 12.45 ? 450 SER B CB 1 ATOM 6887 O OG . SER C 1 398 ? -8.986 99.851 -6.524 1.00 12.61 ? 450 SER B OG 1 ATOM 6888 N N . GLN C 1 399 ? -6.779 102.249 -5.647 1.00 12.40 ? 451 GLN B N 1 ATOM 6889 C CA . GLN C 1 399 ? -6.014 103.275 -6.348 1.00 11.17 ? 451 GLN B CA 1 ATOM 6890 C C . GLN C 1 399 ? -5.127 104.067 -5.387 1.00 11.48 ? 451 GLN B C 1 ATOM 6891 O O . GLN C 1 399 ? -3.931 104.195 -5.619 1.00 12.39 ? 451 GLN B O 1 ATOM 6892 C CB . GLN C 1 399 ? -6.945 104.220 -7.089 1.00 12.90 ? 451 GLN B CB 1 ATOM 6893 C CG . GLN C 1 399 ? -6.244 105.397 -7.733 1.00 14.12 ? 451 GLN B CG 1 ATOM 6894 C CD . GLN C 1 399 ? -7.186 106.205 -8.579 1.00 16.27 ? 451 GLN B CD 1 ATOM 6895 O OE1 . GLN C 1 399 ? -7.888 105.662 -9.433 1.00 15.94 ? 451 GLN B OE1 1 ATOM 6896 N NE2 . GLN C 1 399 ? -7.224 107.515 -8.340 1.00 14.44 ? 451 GLN B NE2 1 ATOM 6897 N N . VAL C 1 400 ? -5.703 104.585 -4.309 1.00 10.51 ? 452 VAL B N 1 ATOM 6898 C CA . VAL C 1 400 ? -4.897 105.342 -3.357 1.00 9.60 ? 452 VAL B CA 1 ATOM 6899 C C . VAL C 1 400 ? -3.960 104.384 -2.619 1.00 12.89 ? 452 VAL B C 1 ATOM 6900 O O . VAL C 1 400 ? -4.278 103.208 -2.422 1.00 11.98 ? 452 VAL B O 1 ATOM 6901 C CB . VAL C 1 400 ? -5.763 106.159 -2.356 1.00 11.85 ? 452 VAL B CB 1 ATOM 6902 C CG1 . VAL C 1 400 ? -6.560 107.224 -3.097 1.00 11.34 ? 452 VAL B CG1 1 ATOM 6903 C CG2 . VAL C 1 400 ? -6.662 105.250 -1.523 1.00 12.82 ? 452 VAL B CG2 1 ATOM 6904 N N . ARG C 1 401 ? -2.795 104.899 -2.233 1.00 11.25 ? 453 ARG B N 1 ATOM 6905 C CA . ARG C 1 401 ? -1.697 104.088 -1.714 1.00 11.33 ? 453 ARG B CA 1 ATOM 6906 C C . ARG C 1 401 ? -1.169 104.558 -0.360 1.00 11.30 ? 453 ARG B C 1 ATOM 6907 O O . ARG C 1 401 ? -0.339 103.882 0.248 1.00 12.87 ? 453 ARG B O 1 ATOM 6908 C CB . ARG C 1 401 ? -0.523 104.094 -2.700 1.00 12.10 ? 453 ARG B CB 1 ATOM 6909 C CG . ARG C 1 401 ? -0.800 103.559 -4.106 1.00 13.45 ? 453 ARG B CG 1 ATOM 6910 C CD . ARG C 1 401 ? -0.910 102.053 -4.145 1.00 16.98 ? 453 ARG B CD 1 ATOM 6911 N NE . ARG C 1 401 ? -2.226 101.621 -3.716 1.00 15.31 ? 453 ARG B NE 1 ATOM 6912 C CZ . ARG C 1 401 ? -2.554 100.365 -3.434 1.00 16.11 ? 453 ARG B CZ 1 ATOM 6913 N NH1 . ARG C 1 401 ? -3.789 100.078 -3.045 1.00 17.09 ? 453 ARG B NH1 1 ATOM 6914 N NH2 . ARG C 1 401 ? -1.653 99.396 -3.541 1.00 15.50 ? 453 ARG B NH2 1 ATOM 6915 N N . GLY C 1 402 ? -1.602 105.733 0.092 1.00 10.34 ? 454 GLY B N 1 ATOM 6916 C CA . GLY C 1 402 ? -1.133 106.274 1.358 1.00 10.68 ? 454 GLY B CA 1 ATOM 6917 C C . GLY C 1 402 ? 0.037 107.226 1.184 1.00 10.65 ? 454 GLY B C 1 ATOM 6918 O O . GLY C 1 402 ? 0.739 107.531 2.151 1.00 13.65 ? 454 GLY B O 1 ATOM 6919 N N . TYR C 1 403 ? 0.252 107.698 -0.040 1.00 10.73 ? 455 TYR B N 1 ATOM 6920 C CA . TYR C 1 403 ? 1.356 108.613 -0.327 1.00 10.01 ? 455 TYR B CA 1 ATOM 6921 C C . TYR C 1 403 ? 0.935 110.053 -0.070 1.00 11.81 ? 455 TYR B C 1 ATOM 6922 O O . TYR C 1 403 ? -0.029 110.521 -0.670 1.00 12.44 ? 455 TYR B O 1 ATOM 6923 C CB . TYR C 1 403 ? 1.814 108.491 -1.784 1.00 10.98 ? 455 TYR B CB 1 ATOM 6924 C CG . TYR C 1 403 ? 2.159 107.101 -2.274 1.00 13.68 ? 455 TYR B CG 1 ATOM 6925 C CD1 . TYR C 1 403 ? 2.543 106.103 -1.396 1.00 12.47 ? 455 TYR B CD1 1 ATOM 6926 C CD2 . TYR C 1 403 ? 2.081 106.799 -3.630 1.00 12.19 ? 455 TYR B CD2 1 ATOM 6927 C CE1 . TYR C 1 403 ? 2.847 104.827 -1.860 1.00 14.30 ? 455 TYR B CE1 1 ATOM 6928 C CE2 . TYR C 1 403 ? 2.386 105.533 -4.099 1.00 12.06 ? 455 TYR B CE2 1 ATOM 6929 C CZ . TYR C 1 403 ? 2.761 104.563 -3.207 1.00 12.18 ? 455 TYR B CZ 1 ATOM 6930 O OH . TYR C 1 403 ? 3.063 103.297 -3.666 1.00 17.64 ? 455 TYR B OH 1 ATOM 6931 N N . HIS C 1 404 ? 1.664 110.776 0.778 1.00 10.77 ? 456 HIS B N 1 ATOM 6932 C CA . HIS C 1 404 ? 1.320 112.176 1.041 1.00 11.11 ? 456 HIS B CA 1 ATOM 6933 C C . HIS C 1 404 ? 2.441 113.148 0.747 1.00 12.11 ? 456 HIS B C 1 ATOM 6934 O O . HIS C 1 404 ? 2.238 114.366 0.829 1.00 11.60 ? 456 HIS B O 1 ATOM 6935 C CB . HIS C 1 404 ? 0.869 112.347 2.485 1.00 11.83 ? 456 HIS B CB 1 ATOM 6936 C CG . HIS C 1 404 ? -0.420 111.661 2.769 1.00 11.30 ? 456 HIS B CG 1 ATOM 6937 N ND1 . HIS C 1 404 ? -1.604 112.048 2.182 1.00 11.22 ? 456 HIS B ND1 1 ATOM 6938 C CD2 . HIS C 1 404 ? -0.701 110.566 3.513 1.00 12.98 ? 456 HIS B CD2 1 ATOM 6939 C CE1 . HIS C 1 404 ? -2.571 111.238 2.580 1.00 10.67 ? 456 HIS B CE1 1 ATOM 6940 N NE2 . HIS C 1 404 ? -2.049 110.332 3.386 1.00 12.08 ? 456 HIS B NE2 1 ATOM 6941 N N . TRP C 1 405 ? 3.599 112.612 0.385 1.00 11.18 ? 457 TRP B N 1 ATOM 6942 C CA . TRP C 1 405 ? 4.788 113.404 0.084 1.00 11.24 ? 457 TRP B CA 1 ATOM 6943 C C . TRP C 1 405 ? 5.455 112.845 -1.161 1.00 11.50 ? 457 TRP B C 1 ATOM 6944 O O . TRP C 1 405 ? 5.567 111.627 -1.315 1.00 11.15 ? 457 TRP B O 1 ATOM 6945 C CB . TRP C 1 405 ? 5.770 113.391 1.266 1.00 9.77 ? 457 TRP B CB 1 ATOM 6946 C CG . TRP C 1 405 ? 5.110 113.677 2.565 1.00 10.26 ? 457 TRP B CG 1 ATOM 6947 C CD1 . TRP C 1 405 ? 4.979 114.896 3.167 1.00 8.26 ? 457 TRP B CD1 1 ATOM 6948 C CD2 . TRP C 1 405 ? 4.461 112.735 3.422 1.00 10.39 ? 457 TRP B CD2 1 ATOM 6949 N NE1 . TRP C 1 405 ? 4.287 114.771 4.343 1.00 10.12 ? 457 TRP B NE1 1 ATOM 6950 C CE2 . TRP C 1 405 ? 3.954 113.453 4.524 1.00 10.77 ? 457 TRP B CE2 1 ATOM 6951 C CE3 . TRP C 1 405 ? 4.258 111.350 3.364 1.00 10.39 ? 457 TRP B CE3 1 ATOM 6952 C CZ2 . TRP C 1 405 ? 3.262 112.833 5.561 1.00 11.24 ? 457 TRP B CZ2 1 ATOM 6953 C CZ3 . TRP C 1 405 ? 3.571 110.744 4.388 1.00 9.95 ? 457 TRP B CZ3 1 ATOM 6954 C CH2 . TRP C 1 405 ? 3.080 111.479 5.471 1.00 11.41 ? 457 TRP B CH2 1 ATOM 6955 N N . ALA C 1 406 ? 5.873 113.728 -2.063 1.00 9.30 ? 458 ALA B N 1 ATOM 6956 C CA . ALA C 1 406 ? 6.646 113.329 -3.221 1.00 8.96 ? 458 ALA B CA 1 ATOM 6957 C C . ALA C 1 406 ? 7.799 114.296 -3.463 1.00 12.66 ? 458 ALA B C 1 ATOM 6958 O O . ALA C 1 406 ? 7.659 115.501 -3.245 1.00 11.10 ? 458 ALA B O 1 ATOM 6959 C CB . ALA C 1 406 ? 5.769 113.249 -4.458 1.00 11.32 ? 458 ALA B CB 1 ATOM 6960 N N . THR C 1 407 ? 8.930 113.753 -3.903 1.00 11.02 ? 459 THR B N 1 ATOM 6961 C CA . THR C 1 407 ? 10.053 114.551 -4.392 1.00 11.21 ? 459 THR B CA 1 ATOM 6962 C C . THR C 1 407 ? 10.159 114.373 -5.892 1.00 13.78 ? 459 THR B C 1 ATOM 6963 O O . THR C 1 407 ? 10.260 113.244 -6.376 1.00 13.62 ? 459 THR B O 1 ATOM 6964 C CB . THR C 1 407 ? 11.377 114.135 -3.728 1.00 13.22 ? 459 THR B CB 1 ATOM 6965 O OG1 . THR C 1 407 ? 11.311 114.405 -2.322 1.00 12.82 ? 459 THR B OG1 1 ATOM 6966 C CG2 . THR C 1 407 ? 12.575 114.880 -4.339 1.00 14.81 ? 459 THR B CG2 1 ATOM 6967 N N . PHE C 1 408 ? 10.113 115.485 -6.622 1.00 12.41 ? 460 PHE B N 1 ATOM 6968 C CA . PHE C 1 408 ? 10.368 115.495 -8.059 1.00 12.29 ? 460 PHE B CA 1 ATOM 6969 C C . PHE C 1 408 ? 11.836 115.820 -8.308 1.00 12.87 ? 460 PHE B C 1 ATOM 6970 O O . PHE C 1 408 ? 12.363 116.783 -7.752 1.00 14.37 ? 460 PHE B O 1 ATOM 6971 C CB . PHE C 1 408 ? 9.468 116.510 -8.751 1.00 11.40 ? 460 PHE B CB 1 ATOM 6972 C CG . PHE C 1 408 ? 9.706 116.633 -10.226 1.00 12.92 ? 460 PHE B CG 1 ATOM 6973 C CD1 . PHE C 1 408 ? 9.169 115.705 -11.098 1.00 16.67 ? 460 PHE B CD1 1 ATOM 6974 C CD2 . PHE C 1 408 ? 10.444 117.690 -10.748 1.00 13.62 ? 460 PHE B CD2 1 ATOM 6975 C CE1 . PHE C 1 408 ? 9.369 115.818 -12.459 1.00 14.80 ? 460 PHE B CE1 1 ATOM 6976 C CE2 . PHE C 1 408 ? 10.644 117.801 -12.111 1.00 14.21 ? 460 PHE B CE2 1 ATOM 6977 C CZ . PHE C 1 408 ? 10.108 116.864 -12.965 1.00 15.46 ? 460 PHE B CZ 1 ATOM 6978 N N . VAL C 1 409 ? 12.495 115.007 -9.126 1.00 13.51 ? 461 VAL B N 1 ATOM 6979 C CA . VAL C 1 409 ? 13.892 115.223 -9.481 1.00 13.35 ? 461 VAL B CA 1 ATOM 6980 C C . VAL C 1 409 ? 13.976 115.428 -10.985 1.00 16.47 ? 461 VAL B C 1 ATOM 6981 O O . VAL C 1 409 ? 13.779 114.496 -11.768 1.00 14.37 ? 461 VAL B O 1 ATOM 6982 C CB . VAL C 1 409 ? 14.785 114.042 -9.044 1.00 15.38 ? 461 VAL B CB 1 ATOM 6983 C CG1 . VAL C 1 409 ? 16.245 114.350 -9.323 1.00 16.96 ? 461 VAL B CG1 1 ATOM 6984 C CG2 . VAL C 1 409 ? 14.578 113.740 -7.566 1.00 13.30 ? 461 VAL B CG2 1 ATOM 6985 N N . ALA C 1 410 ? 14.256 116.664 -11.391 1.00 14.92 ? 462 ALA B N 1 ATOM 6986 C CA . ALA C 1 410 ? 14.338 117.004 -12.803 1.00 14.09 ? 462 ALA B CA 1 ATOM 6987 C C . ALA C 1 410 ? 15.556 116.372 -13.434 1.00 18.11 ? 462 ALA B C 1 ATOM 6988 O O . ALA C 1 410 ? 16.602 116.249 -12.796 1.00 19.51 ? 462 ALA B O 1 ATOM 6989 C CB . ALA C 1 410 ? 14.379 118.510 -12.984 1.00 16.23 ? 462 ALA B CB 1 ATOM 6990 N N . THR C 1 411 ? 15.422 115.979 -14.696 1.00 19.30 ? 463 THR B N 1 ATOM 6991 C CA . THR C 1 411 ? 16.541 115.401 -15.425 1.00 22.55 ? 463 THR B CA 1 ATOM 6992 C C . THR C 1 411 ? 17.689 116.405 -15.520 1.00 25.24 ? 463 THR B C 1 ATOM 6993 O O . THR C 1 411 ? 18.836 116.057 -15.238 1.00 29.25 ? 463 THR B O 1 ATOM 6994 C CB . THR C 1 411 ? 16.113 114.941 -16.828 1.00 25.70 ? 463 THR B CB 1 ATOM 6995 O OG1 . THR C 1 411 ? 15.100 113.935 -16.707 1.00 23.86 ? 463 THR B OG1 1 ATOM 6996 C CG2 . THR C 1 411 ? 17.298 114.363 -17.601 1.00 31.90 ? 463 THR B CG2 1 ATOM 6997 N N . ASP C 1 412 ? 17.390 117.647 -15.897 1.00 23.82 ? 464 ASP B N 1 ATOM 6998 C CA . ASP C 1 412 ? 18.431 118.674 -15.988 1.00 26.39 ? 464 ASP B CA 1 ATOM 6999 C C . ASP C 1 412 ? 17.853 120.093 -16.032 1.00 32.12 ? 464 ASP B C 1 ATOM 7000 O O . ASP C 1 412 ? 18.147 120.878 -16.933 1.00 40.77 ? 464 ASP B O 1 ATOM 7001 C CB . ASP C 1 412 ? 19.317 118.424 -17.214 1.00 42.89 ? 464 ASP B CB 1 ATOM 7002 C CG . ASP C 1 412 ? 18.515 118.182 -18.477 1.00 44.09 ? 464 ASP B CG 1 ATOM 7003 O OD1 . ASP C 1 412 ? 17.455 118.823 -18.648 1.00 47.07 ? 464 ASP B OD1 1 ATOM 7004 O OD2 . ASP C 1 412 ? 18.946 117.346 -19.301 1.00 56.04 ? 464 ASP B OD2 1 ATOM 7005 N N . CYS C 1 413 ? 17.031 120.404 -15.040 1.00 21.67 ? 465 CYS B N 1 ATOM 7006 C CA . CYS C 1 413 ? 16.463 121.735 -14.862 1.00 17.07 ? 465 CYS B CA 1 ATOM 7007 C C . CYS C 1 413 ? 16.650 122.150 -13.411 1.00 20.20 ? 465 CYS B C 1 ATOM 7008 O O . CYS C 1 413 ? 16.409 121.355 -12.506 1.00 18.65 ? 465 CYS B O 1 ATOM 7009 C CB . CYS C 1 413 ? 14.970 121.749 -15.230 1.00 19.43 ? 465 CYS B CB 1 ATOM 7010 S SG . CYS C 1 413 ? 14.037 123.178 -14.606 1.00 23.55 ? 465 CYS B SG 1 ATOM 7011 N N . ASN C 1 414 ? 17.089 123.382 -13.176 1.00 17.28 ? 466 ASN B N 1 ATOM 7012 C CA . ASN C 1 414 ? 17.044 123.926 -11.828 1.00 16.51 ? 466 ASN B CA 1 ATOM 7013 C C . ASN C 1 414 ? 15.605 124.325 -11.551 1.00 15.44 ? 466 ASN B C 1 ATOM 7014 O O . ASN C 1 414 ? 15.054 125.171 -12.249 1.00 16.36 ? 466 ASN B O 1 ATOM 7015 C CB . ASN C 1 414 ? 17.979 125.126 -11.662 1.00 16.10 ? 466 ASN B CB 1 ATOM 7016 C CG . ASN C 1 414 ? 18.001 125.649 -10.239 1.00 18.05 ? 466 ASN B CG 1 ATOM 7017 O OD1 . ASN C 1 414 ? 16.960 125.996 -9.679 1.00 18.29 ? 466 ASN B OD1 1 ATOM 7018 N ND2 . ASN C 1 414 ? 19.187 125.692 -9.638 1.00 20.86 ? 466 ASN B ND2 1 ATOM 7019 N N . MET C 1 415 ? 14.988 123.711 -10.546 1.00 13.35 ? 467 MET B N 1 ATOM 7020 C CA . MET C 1 415 ? 13.542 123.807 -10.396 1.00 15.24 ? 467 MET B CA 1 ATOM 7021 C C . MET C 1 415 ? 13.073 125.114 -9.770 1.00 15.83 ? 467 MET B C 1 ATOM 7022 O O . MET C 1 415 ? 11.876 125.313 -9.563 1.00 14.75 ? 467 MET B O 1 ATOM 7023 C CB . MET C 1 415 ? 13.025 122.619 -9.578 1.00 14.39 ? 467 MET B CB 1 ATOM 7024 C CG . MET C 1 415 ? 13.079 121.310 -10.356 1.00 17.05 ? 467 MET B CG 1 ATOM 7025 S SD . MET C 1 415 ? 12.121 121.338 -11.885 1.00 15.84 ? 467 MET B SD 1 ATOM 7026 C CE . MET C 1 415 ? 10.484 121.557 -11.221 1.00 14.96 ? 467 MET B CE 1 ATOM 7027 N N . GLY C 1 416 ? 14.016 126.015 -9.503 1.00 14.37 ? 468 GLY B N 1 ATOM 7028 C CA . GLY C 1 416 ? 13.683 127.382 -9.147 1.00 16.74 ? 468 GLY B CA 1 ATOM 7029 C C . GLY C 1 416 ? 13.684 128.321 -10.347 1.00 16.15 ? 468 GLY B C 1 ATOM 7030 O O . GLY C 1 416 ? 13.318 129.492 -10.223 1.00 19.03 ? 468 GLY B O 1 ATOM 7031 N N . GLU C 1 417 ? 14.075 127.806 -11.512 1.00 14.40 ? 469 GLU B N 1 ATOM 7032 C CA . GLU C 1 417 ? 14.211 128.624 -12.719 1.00 16.04 ? 469 GLU B CA 1 ATOM 7033 C C . GLU C 1 417 ? 13.041 128.406 -13.688 1.00 17.83 ? 469 GLU B C 1 ATOM 7034 O O . GLU C 1 417 ? 12.162 127.586 -13.431 1.00 18.16 ? 469 GLU B O 1 ATOM 7035 C CB . GLU C 1 417 ? 15.550 128.319 -13.402 1.00 18.81 ? 469 GLU B CB 1 ATOM 7036 C CG . GLU C 1 417 ? 16.767 128.596 -12.524 1.00 16.98 ? 469 GLU B CG 1 ATOM 7037 C CD . GLU C 1 417 ? 16.900 130.063 -12.156 1.00 19.22 ? 469 GLU B CD 1 ATOM 7038 O OE1 . GLU C 1 417 ? 16.794 130.912 -13.066 1.00 21.84 ? 469 GLU B OE1 1 ATOM 7039 O OE2 . GLU C 1 417 ? 17.109 130.362 -10.959 1.00 21.22 ? 469 GLU B OE2 1 ATOM 7040 N N . SER C 1 418 ? 13.024 129.155 -14.790 1.00 19.25 ? 470 SER B N 1 ATOM 7041 C CA . SER C 1 418 ? 11.870 129.186 -15.687 1.00 19.14 ? 470 SER B CA 1 ATOM 7042 C C . SER C 1 418 ? 11.596 127.845 -16.366 1.00 18.00 ? 470 SER B C 1 ATOM 7043 O O . SER C 1 418 ? 10.490 127.612 -16.844 1.00 23.94 ? 470 SER B O 1 ATOM 7044 C CB . SER C 1 418 ? 12.063 130.261 -16.758 1.00 21.36 ? 470 SER B CB 1 ATOM 7045 O OG . SER C 1 418 ? 13.176 129.966 -17.579 1.00 27.22 ? 470 SER B OG 1 ATOM 7046 N N . CYS C 1 419 ? 12.595 126.971 -16.401 1.00 18.30 ? 471 CYS B N 1 ATOM 7047 C CA . CYS C 1 419 ? 12.432 125.644 -16.987 1.00 18.94 ? 471 CYS B CA 1 ATOM 7048 C C . CYS C 1 419 ? 11.514 124.754 -16.149 1.00 19.42 ? 471 CYS B C 1 ATOM 7049 O O . CYS C 1 419 ? 11.084 123.695 -16.609 1.00 18.62 ? 471 CYS B O 1 ATOM 7050 C CB . CYS C 1 419 ? 13.793 124.963 -17.147 1.00 21.69 ? 471 CYS B CB 1 ATOM 7051 S SG . CYS C 1 419 ? 14.745 124.821 -15.597 1.00 23.68 ? 471 CYS B SG 1 ATOM 7052 N N . ALA C 1 420 ? 11.224 125.166 -14.920 1.00 17.69 ? 472 ALA B N 1 ATOM 7053 C CA . ALA C 1 420 ? 10.541 124.284 -13.981 1.00 15.95 ? 472 ALA B CA 1 ATOM 7054 C C . ALA C 1 420 ? 9.179 123.822 -14.494 1.00 18.43 ? 472 ALA B C 1 ATOM 7055 O O . ALA C 1 420 ? 8.769 122.692 -14.228 1.00 19.41 ? 472 ALA B O 1 ATOM 7056 C CB . ALA C 1 420 ? 10.384 124.968 -12.637 1.00 16.22 ? 472 ALA B CB 1 ATOM 7057 N N . ALA C 1 421 ? 8.496 124.683 -15.241 1.00 19.10 ? 473 ALA B N 1 ATOM 7058 C CA . ALA C 1 421 ? 7.127 124.407 -15.667 1.00 21.26 ? 473 ALA B CA 1 ATOM 7059 C C . ALA C 1 421 ? 7.040 123.325 -16.737 1.00 19.46 ? 473 ALA B C 1 ATOM 7060 O O . ALA C 1 421 ? 5.975 122.737 -16.926 1.00 21.59 ? 473 ALA B O 1 ATOM 7061 C CB . ALA C 1 421 ? 6.475 125.683 -16.178 1.00 26.60 ? 473 ALA B CB 1 ATOM 7062 N N . THR C 1 422 ? 8.142 123.067 -17.439 1.00 18.23 ? 474 THR B N 1 ATOM 7063 C CA . THR C 1 422 ? 8.123 122.092 -18.528 1.00 19.04 ? 474 THR B CA 1 ATOM 7064 C C . THR C 1 422 ? 9.149 120.975 -18.372 1.00 19.26 ? 474 THR B C 1 ATOM 7065 O O . THR C 1 422 ? 9.186 120.050 -19.188 1.00 22.72 ? 474 THR B O 1 ATOM 7066 C CB . THR C 1 422 ? 8.353 122.778 -19.885 1.00 22.46 ? 474 THR B CB 1 ATOM 7067 O OG1 . THR C 1 422 ? 9.563 123.544 -19.844 1.00 22.18 ? 474 THR B OG1 1 ATOM 7068 C CG2 . THR C 1 422 ? 7.189 123.692 -20.210 1.00 22.53 ? 474 THR B CG2 1 ATOM 7069 N N . ALA C 1 423 ? 9.963 121.046 -17.322 1.00 16.39 ? 475 ALA B N 1 ATOM 7070 C CA . ALA C 1 423 ? 10.987 120.042 -17.067 1.00 16.20 ? 475 ALA B CA 1 ATOM 7071 C C . ALA C 1 423 ? 10.369 118.666 -16.884 1.00 14.35 ? 475 ALA B C 1 ATOM 7072 O O . ALA C 1 423 ? 9.298 118.545 -16.299 1.00 15.79 ? 475 ALA B O 1 ATOM 7073 C CB . ALA C 1 423 ? 11.792 120.409 -15.834 1.00 19.04 ? 475 ALA B CB 1 ATOM 7074 N N . ARG C 1 424 ? 11.040 117.647 -17.403 1.00 19.04 ? 476 ARG B N 1 ATOM 7075 C CA . ARG C 1 424 ? 10.657 116.268 -17.120 1.00 18.44 ? 476 ARG B CA 1 ATOM 7076 C C . ARG C 1 424 ? 11.658 115.653 -16.159 1.00 17.32 ? 476 ARG B C 1 ATOM 7077 O O . ARG C 1 424 ? 12.797 116.116 -16.038 1.00 19.33 ? 476 ARG B O 1 ATOM 7078 C CB . ARG C 1 424 ? 10.563 115.445 -18.406 1.00 20.77 ? 476 ARG B CB 1 ATOM 7079 C CG . ARG C 1 424 ? 9.627 116.051 -19.444 1.00 27.20 ? 476 ARG B CG 1 ATOM 7080 C CD . ARG C 1 424 ? 9.139 115.015 -20.434 1.00 30.71 ? 476 ARG B CD 1 ATOM 7081 N NE . ARG C 1 424 ? 8.052 114.221 -19.869 1.00 33.55 ? 476 ARG B NE 1 ATOM 7082 C CZ . ARG C 1 424 ? 6.766 114.554 -19.927 1.00 31.81 ? 476 ARG B CZ 1 ATOM 7083 N NH1 . ARG C 1 424 ? 5.854 113.766 -19.373 1.00 26.52 ? 476 ARG B NH1 1 ATOM 7084 N NH2 . ARG C 1 424 ? 6.387 115.670 -20.531 1.00 37.50 ? 476 ARG B NH2 1 ATOM 7085 N N . GLY C 1 425 ? 11.226 114.615 -15.454 1.00 15.36 ? 477 GLY B N 1 ATOM 7086 C CA . GLY C 1 425 ? 12.066 113.985 -14.458 1.00 16.37 ? 477 GLY B CA 1 ATOM 7087 C C . GLY C 1 425 ? 11.377 112.820 -13.791 1.00 17.14 ? 477 GLY B C 1 ATOM 7088 O O . GLY C 1 425 ? 10.423 112.247 -14.334 1.00 17.16 ? 477 GLY B O 1 ATOM 7089 N N . LYS C 1 426 ? 11.854 112.488 -12.599 1.00 13.30 ? 478 LYS B N 1 ATOM 7090 C CA . LYS C 1 426 ? 11.358 111.337 -11.858 1.00 13.32 ? 478 LYS B CA 1 ATOM 7091 C C . LYS C 1 426 ? 10.629 111.786 -10.586 1.00 16.74 ? 478 LYS B C 1 ATOM 7092 O O . LYS C 1 426 ? 11.098 112.670 -9.866 1.00 16.25 ? 478 LYS B O 1 ATOM 7093 C CB . LYS C 1 426 ? 12.521 110.387 -11.534 1.00 20.87 ? 478 LYS B CB 1 ATOM 7094 C CG . LYS C 1 426 ? 12.102 108.946 -11.283 1.00 24.88 ? 478 LYS B CG 1 ATOM 7095 C CD . LYS C 1 426 ? 13.291 107.984 -11.335 1.00 23.58 ? 478 LYS B CD 1 ATOM 7096 C CE . LYS C 1 426 ? 12.933 106.638 -10.690 1.00 29.77 ? 478 LYS B CE 1 ATOM 7097 N NZ . LYS C 1 426 ? 14.005 105.595 -10.795 1.00 37.08 ? 478 LYS B NZ 1 ATOM 7098 N N . CYS C 1 427 ? 9.461 111.187 -10.358 1.00 12.78 ? 479 CYS B N 1 ATOM 7099 C CA A CYS C 1 427 ? 8.660 111.427 -9.167 0.44 14.02 ? 479 CYS B CA 1 ATOM 7100 C CA B CYS C 1 427 ? 8.661 111.400 -9.144 0.56 13.94 ? 479 CYS B CA 1 ATOM 7101 C C . CYS C 1 427 ? 8.870 110.278 -8.168 1.00 16.84 ? 479 CYS B C 1 ATOM 7102 O O . CYS C 1 427 ? 8.672 109.120 -8.521 1.00 17.73 ? 479 CYS B O 1 ATOM 7103 C CB A CYS C 1 427 ? 7.184 111.564 -9.574 0.44 16.40 ? 479 CYS B CB 1 ATOM 7104 C CB B CYS C 1 427 ? 7.165 111.443 -9.431 0.56 16.44 ? 479 CYS B CB 1 ATOM 7105 S SG A CYS C 1 427 ? 6.073 112.279 -8.340 0.44 14.15 ? 479 CYS B SG 1 ATOM 7106 S SG B CYS C 1 427 ? 6.639 112.283 -10.891 0.56 22.33 ? 479 CYS B SG 1 ATOM 7107 N N . PHE C 1 428 ? 9.256 110.609 -6.938 1.00 13.57 ? 480 PHE B N 1 ATOM 7108 C CA . PHE C 1 428 ? 9.416 109.621 -5.872 1.00 11.23 ? 480 PHE B CA 1 ATOM 7109 C C . PHE C 1 428 ? 8.342 109.827 -4.821 1.00 12.48 ? 480 PHE B C 1 ATOM 7110 O O . PHE C 1 428 ? 8.219 110.920 -4.267 1.00 13.66 ? 480 PHE B O 1 ATOM 7111 C CB . PHE C 1 428 ? 10.801 109.718 -5.235 1.00 15.60 ? 480 PHE B CB 1 ATOM 7112 C CG . PHE C 1 428 ? 11.920 109.417 -6.186 1.00 15.22 ? 480 PHE B CG 1 ATOM 7113 C CD1 . PHE C 1 428 ? 12.368 108.119 -6.348 1.00 12.90 ? 480 PHE B CD1 1 ATOM 7114 C CD2 . PHE C 1 428 ? 12.525 110.424 -6.923 1.00 14.07 ? 480 PHE B CD2 1 ATOM 7115 C CE1 . PHE C 1 428 ? 13.390 107.826 -7.221 1.00 14.75 ? 480 PHE B CE1 1 ATOM 7116 C CE2 . PHE C 1 428 ? 13.547 110.132 -7.803 1.00 15.43 ? 480 PHE B CE2 1 ATOM 7117 C CZ . PHE C 1 428 ? 13.986 108.829 -7.949 1.00 13.92 ? 480 PHE B CZ 1 ATOM 7118 N N . PHE C 1 429 ? 7.563 108.780 -4.556 1.00 10.88 ? 481 PHE B N 1 ATOM 7119 C CA . PHE C 1 429 ? 6.433 108.848 -3.633 1.00 11.32 ? 481 PHE B CA 1 ATOM 7120 C C . PHE C 1 429 ? 6.750 108.223 -2.285 1.00 13.39 ? 481 PHE B C 1 ATOM 7121 O O . PHE C 1 429 ? 7.360 107.150 -2.213 1.00 11.90 ? 481 PHE B O 1 ATOM 7122 C CB . PHE C 1 429 ? 5.213 108.140 -4.233 1.00 10.23 ? 481 PHE B CB 1 ATOM 7123 C CG . PHE C 1 429 ? 4.764 108.700 -5.537 1.00 13.65 ? 481 PHE B CG 1 ATOM 7124 C CD1 . PHE C 1 429 ? 4.059 109.888 -5.592 1.00 16.08 ? 481 PHE B CD1 1 ATOM 7125 C CD2 . PHE C 1 429 ? 5.026 108.037 -6.720 1.00 16.78 ? 481 PHE B CD2 1 ATOM 7126 C CE1 . PHE C 1 429 ? 3.640 110.404 -6.803 1.00 17.97 ? 481 PHE B CE1 1 ATOM 7127 C CE2 . PHE C 1 429 ? 4.607 108.550 -7.931 1.00 19.15 ? 481 PHE B CE2 1 ATOM 7128 C CZ . PHE C 1 429 ? 3.911 109.733 -7.972 1.00 17.58 ? 481 PHE B CZ 1 ATOM 7129 N N . TYR C 1 430 ? 6.281 108.869 -1.220 1.00 12.28 ? 482 TYR B N 1 ATOM 7130 C CA . TYR C 1 430 ? 6.584 108.464 0.144 1.00 12.19 ? 482 TYR B CA 1 ATOM 7131 C C . TYR C 1 430 ? 5.356 108.311 1.031 1.00 11.66 ? 482 TYR B C 1 ATOM 7132 O O . TYR C 1 430 ? 4.378 109.039 0.873 1.00 11.78 ? 482 TYR B O 1 ATOM 7133 C CB . TYR C 1 430 ? 7.500 109.491 0.801 1.00 11.41 ? 482 TYR B CB 1 ATOM 7134 C CG . TYR C 1 430 ? 8.752 109.805 0.017 1.00 12.27 ? 482 TYR B CG 1 ATOM 7135 C CD1 . TYR C 1 430 ? 9.770 108.869 -0.093 1.00 12.67 ? 482 TYR B CD1 1 ATOM 7136 C CD2 . TYR C 1 430 ? 8.922 111.043 -0.607 1.00 13.14 ? 482 TYR B CD2 1 ATOM 7137 C CE1 . TYR C 1 430 ? 10.921 109.148 -0.803 1.00 14.56 ? 482 TYR B CE1 1 ATOM 7138 C CE2 . TYR C 1 430 ? 10.060 111.327 -1.315 1.00 13.11 ? 482 TYR B CE2 1 ATOM 7139 C CZ . TYR C 1 430 ? 11.058 110.381 -1.413 1.00 13.90 ? 482 TYR B CZ 1 ATOM 7140 O OH . TYR C 1 430 ? 12.194 110.677 -2.124 1.00 14.36 ? 482 TYR B OH 1 ATOM 7141 N N . SER C 1 431 ? 5.427 107.375 1.976 1.00 12.23 ? 483 SER B N 1 ATOM 7142 C CA . SER C 1 431 ? 4.412 107.239 3.022 1.00 12.48 ? 483 SER B CA 1 ATOM 7143 C C . SER C 1 431 ? 5.001 107.489 4.421 1.00 13.21 ? 483 SER B C 1 ATOM 7144 O O . SER C 1 431 ? 4.315 107.313 5.425 1.00 15.24 ? 483 SER B O 1 ATOM 7145 C CB . SER C 1 431 ? 3.766 105.852 2.961 1.00 16.31 ? 483 SER B CB 1 ATOM 7146 O OG . SER C 1 431 ? 4.740 104.854 3.167 1.00 16.35 ? 483 SER B OG 1 ATOM 7147 N N . THR C 1 432 ? 6.263 107.913 4.472 1.00 13.53 ? 484 THR B N 1 ATOM 7148 C CA . THR C 1 432 ? 6.961 108.214 5.724 1.00 14.12 ? 484 THR B CA 1 ATOM 7149 C C . THR C 1 432 ? 6.778 109.680 6.107 1.00 13.16 ? 484 THR B C 1 ATOM 7150 O O . THR C 1 432 ? 6.906 110.555 5.252 1.00 14.34 ? 484 THR B O 1 ATOM 7151 C CB . THR C 1 432 ? 8.467 107.935 5.587 1.00 16.02 ? 484 THR B CB 1 ATOM 7152 O OG1 . THR C 1 432 ? 8.679 106.554 5.268 1.00 20.74 ? 484 THR B OG1 1 ATOM 7153 C CG2 . THR C 1 432 ? 9.219 108.282 6.877 1.00 18.96 ? 484 THR B CG2 1 ATOM 7154 N N . VAL C 1 433 ? 6.501 109.951 7.378 1.00 12.98 ? 485 VAL B N 1 ATOM 7155 C CA . VAL C 1 433 ? 6.395 111.327 7.857 1.00 13.83 ? 485 VAL B CA 1 ATOM 7156 C C . VAL C 1 433 ? 7.777 111.995 7.813 1.00 13.41 ? 485 VAL B C 1 ATOM 7157 O O . VAL C 1 433 ? 8.722 111.491 8.419 1.00 13.95 ? 485 VAL B O 1 ATOM 7158 C CB . VAL C 1 433 ? 5.826 111.370 9.283 1.00 14.22 ? 485 VAL B CB 1 ATOM 7159 C CG1 . VAL C 1 433 ? 5.863 112.789 9.840 1.00 15.61 ? 485 VAL B CG1 1 ATOM 7160 C CG2 . VAL C 1 433 ? 4.400 110.852 9.296 1.00 14.26 ? 485 VAL B CG2 1 ATOM 7161 N N . PRO C 1 434 ? 7.910 113.129 7.095 1.00 11.37 ? 486 PRO B N 1 ATOM 7162 C CA . PRO C 1 434 ? 9.224 113.780 6.960 1.00 12.24 ? 486 PRO B CA 1 ATOM 7163 C C . PRO C 1 434 ? 9.655 114.562 8.202 1.00 13.52 ? 486 PRO B C 1 ATOM 7164 O O . PRO C 1 434 ? 8.815 115.090 8.934 1.00 13.18 ? 486 PRO B O 1 ATOM 7165 C CB . PRO C 1 434 ? 9.022 114.727 5.772 1.00 11.21 ? 486 PRO B CB 1 ATOM 7166 C CG . PRO C 1 434 ? 7.589 115.078 5.828 1.00 12.64 ? 486 PRO B CG 1 ATOM 7167 C CD . PRO C 1 434 ? 6.886 113.809 6.276 1.00 11.80 ? 486 PRO B CD 1 ATOM 7168 N N . GLU C 1 435 ? 10.966 114.641 8.411 1.00 12.28 ? 487 GLU B N 1 ATOM 7169 C CA . GLU C 1 435 ? 11.536 115.309 9.583 1.00 13.58 ? 487 GLU B CA 1 ATOM 7170 C C . GLU C 1 435 ? 12.467 116.453 9.209 1.00 15.43 ? 487 GLU B C 1 ATOM 7171 O O . GLU C 1 435 ? 12.837 117.263 10.064 1.00 14.06 ? 487 GLU B O 1 ATOM 7172 C CB . GLU C 1 435 ? 12.303 114.293 10.436 1.00 14.09 ? 487 GLU B CB 1 ATOM 7173 C CG . GLU C 1 435 ? 11.480 113.064 10.810 1.00 15.53 ? 487 GLU B CG 1 ATOM 7174 C CD . GLU C 1 435 ? 12.320 111.960 11.433 1.00 18.28 ? 487 GLU B CD 1 ATOM 7175 O OE1 . GLU C 1 435 ? 13.553 112.118 11.539 1.00 17.72 ? 487 GLU B OE1 1 ATOM 7176 O OE2 . GLU C 1 435 ? 11.736 110.921 11.810 1.00 22.70 ? 487 GLU B OE2 1 ATOM 7177 N N . CYS C 1 436 ? 12.852 116.505 7.941 1.00 12.56 ? 488 CYS B N 1 ATOM 7178 C CA . CYS C 1 436 ? 13.799 117.495 7.466 1.00 13.65 ? 488 CYS B CA 1 ATOM 7179 C C . CYS C 1 436 ? 13.808 117.538 5.950 1.00 13.07 ? 488 CYS B C 1 ATOM 7180 O O . CYS C 1 436 ? 13.153 116.736 5.273 1.00 13.56 ? 488 CYS B O 1 ATOM 7181 C CB . CYS C 1 436 ? 15.205 117.198 8.003 1.00 12.77 ? 488 CYS B CB 1 ATOM 7182 S SG . CYS C 1 436 ? 15.864 115.552 7.572 1.00 17.91 ? 488 CYS B SG 1 ATOM 7183 N N . LEU C 1 437 ? 14.546 118.500 5.416 1.00 12.47 ? 489 LEU B N 1 ATOM 7184 C CA . LEU C 1 437 ? 14.658 118.707 3.982 1.00 12.83 ? 489 LEU B CA 1 ATOM 7185 C C . LEU C 1 437 ? 16.120 118.835 3.568 1.00 13.69 ? 489 LEU B C 1 ATOM 7186 O O . LEU C 1 437 ? 16.949 119.355 4.330 1.00 14.13 ? 489 LEU B O 1 ATOM 7187 C CB . LEU C 1 437 ? 13.877 119.965 3.572 1.00 12.83 ? 489 LEU B CB 1 ATOM 7188 C CG . LEU C 1 437 ? 12.370 119.940 3.825 1.00 12.92 ? 489 LEU B CG 1 ATOM 7189 C CD1 . LEU C 1 437 ? 11.755 121.326 3.705 1.00 16.72 ? 489 LEU B CD1 1 ATOM 7190 C CD2 . LEU C 1 437 ? 11.720 118.988 2.848 1.00 17.13 ? 489 LEU B CD2 1 ATOM 7191 N N . ILE C 1 438 ? 16.433 118.351 2.367 1.00 13.60 ? 490 ILE B N 1 ATOM 7192 C CA . ILE C 1 438 ? 17.762 118.481 1.774 1.00 13.41 ? 490 ILE B CA 1 ATOM 7193 C C . ILE C 1 438 ? 17.672 119.431 0.599 1.00 13.27 ? 490 ILE B C 1 ATOM 7194 O O . ILE C 1 438 ? 16.837 119.248 -0.282 1.00 13.96 ? 490 ILE B O 1 ATOM 7195 C CB . ILE C 1 438 ? 18.308 117.135 1.284 1.00 15.86 ? 490 ILE B CB 1 ATOM 7196 C CG1 . ILE C 1 438 ? 18.355 116.126 2.429 1.00 18.91 ? 490 ILE B CG1 1 ATOM 7197 C CG2 . ILE C 1 438 ? 19.705 117.303 0.683 1.00 17.81 ? 490 ILE B CG2 1 ATOM 7198 C CD1 . ILE C 1 438 ? 18.485 114.696 1.955 1.00 18.81 ? 490 ILE B CD1 1 ATOM 7199 N N . HIS C 1 439 ? 18.526 120.449 0.572 1.00 15.32 ? 491 HIS B N 1 ATOM 7200 C CA . HIS C 1 439 ? 18.527 121.372 -0.551 1.00 16.88 ? 491 HIS B CA 1 ATOM 7201 C C . HIS C 1 439 ? 19.138 120.726 -1.793 1.00 17.18 ? 491 HIS B C 1 ATOM 7202 O O . HIS C 1 439 ? 20.133 120.003 -1.703 1.00 19.13 ? 491 HIS B O 1 ATOM 7203 C CB . HIS C 1 439 ? 19.288 122.653 -0.204 1.00 18.48 ? 491 HIS B CB 1 ATOM 7204 C CG . HIS C 1 439 ? 19.244 123.678 -1.292 1.00 23.88 ? 491 HIS B CG 1 ATOM 7205 N ND1 . HIS C 1 439 ? 20.156 123.703 -2.325 1.00 28.46 ? 491 HIS B ND1 1 ATOM 7206 C CD2 . HIS C 1 439 ? 18.375 124.687 -1.532 1.00 24.35 ? 491 HIS B CD2 1 ATOM 7207 C CE1 . HIS C 1 439 ? 19.860 124.694 -3.146 1.00 26.33 ? 491 HIS B CE1 1 ATOM 7208 N NE2 . HIS C 1 439 ? 18.785 125.308 -2.687 1.00 24.48 ? 491 HIS B NE2 1 ATOM 7209 N N . SER C 1 440 ? 18.532 120.983 -2.952 1.00 13.96 ? 492 SER B N 1 ATOM 7210 C CA . SER C 1 440 ? 19.082 120.542 -4.227 1.00 16.78 ? 492 SER B CA 1 ATOM 7211 C C . SER C 1 440 ? 18.653 121.459 -5.367 1.00 17.01 ? 492 SER B C 1 ATOM 7212 O O . SER C 1 440 ? 17.522 121.929 -5.389 1.00 19.09 ? 492 SER B O 1 ATOM 7213 C CB . SER C 1 440 ? 18.644 119.109 -4.542 1.00 18.39 ? 492 SER B CB 1 ATOM 7214 O OG . SER C 1 440 ? 18.986 118.771 -5.876 1.00 20.04 ? 492 SER B OG 1 ATOM 7215 N N . PRO C 1 441 ? 19.553 121.712 -6.326 1.00 14.56 ? 493 PRO B N 1 ATOM 7216 C CA . PRO C 1 441 ? 19.152 122.577 -7.438 1.00 17.41 ? 493 PRO B CA 1 ATOM 7217 C C . PRO C 1 441 ? 18.057 121.984 -8.324 1.00 16.21 ? 493 PRO B C 1 ATOM 7218 O O . PRO C 1 441 ? 17.291 122.745 -8.900 1.00 15.99 ? 493 PRO B O 1 ATOM 7219 C CB . PRO C 1 441 ? 20.453 122.756 -8.235 1.00 21.70 ? 493 PRO B CB 1 ATOM 7220 C CG . PRO C 1 441 ? 21.316 121.624 -7.846 1.00 27.12 ? 493 PRO B CG 1 ATOM 7221 C CD . PRO C 1 441 ? 20.960 121.294 -6.425 1.00 19.83 ? 493 PRO B CD 1 ATOM 7222 N N . THR C 1 442 ? 17.957 120.662 -8.409 1.00 16.18 ? 494 THR B N 1 ATOM 7223 C CA . THR C 1 442 ? 17.126 120.053 -9.439 1.00 15.86 ? 494 THR B CA 1 ATOM 7224 C C . THR C 1 442 ? 15.856 119.396 -8.909 1.00 14.00 ? 494 THR B C 1 ATOM 7225 O O . THR C 1 442 ? 15.233 118.608 -9.623 1.00 16.23 ? 494 THR B O 1 ATOM 7226 C CB . THR C 1 442 ? 17.924 119.002 -10.226 1.00 17.03 ? 494 THR B CB 1 ATOM 7227 O OG1 . THR C 1 442 ? 18.509 118.071 -9.315 1.00 21.74 ? 494 THR B OG1 1 ATOM 7228 C CG2 . THR C 1 442 ? 19.033 119.670 -11.031 1.00 20.15 ? 494 THR B CG2 1 ATOM 7229 N N . THR C 1 443 ? 15.447 119.735 -7.688 1.00 13.33 ? 495 THR B N 1 ATOM 7230 C CA . THR C 1 443 ? 14.301 119.066 -7.075 1.00 13.97 ? 495 THR B CA 1 ATOM 7231 C C . THR C 1 443 ? 13.191 120.009 -6.616 1.00 12.78 ? 495 THR B C 1 ATOM 7232 O O . THR C 1 443 ? 13.370 121.222 -6.518 1.00 14.70 ? 495 THR B O 1 ATOM 7233 C CB . THR C 1 443 ? 14.746 118.205 -5.871 1.00 13.45 ? 495 THR B CB 1 ATOM 7234 O OG1 . THR C 1 443 ? 15.178 119.043 -4.795 1.00 15.00 ? 495 THR B OG1 1 ATOM 7235 C CG2 . THR C 1 443 ? 15.873 117.267 -6.274 1.00 16.73 ? 495 THR B CG2 1 ATOM 7236 N N . MET C 1 444 ? 12.021 119.426 -6.373 1.00 12.93 ? 496 MET B N 1 ATOM 7237 C CA . MET C 1 444 ? 10.859 120.134 -5.852 1.00 11.11 ? 496 MET B CA 1 ATOM 7238 C C . MET C 1 444 ? 10.054 119.164 -5.000 1.00 12.90 ? 496 MET B C 1 ATOM 7239 O O . MET C 1 444 ? 9.930 117.997 -5.363 1.00 14.54 ? 496 MET B O 1 ATOM 7240 C CB . MET C 1 444 ? 9.993 120.684 -6.986 1.00 12.71 ? 496 MET B CB 1 ATOM 7241 C CG . MET C 1 444 ? 8.760 121.438 -6.522 1.00 11.80 ? 496 MET B CG 1 ATOM 7242 S SD . MET C 1 444 ? 7.961 122.338 -7.857 1.00 13.46 ? 496 MET B SD 1 ATOM 7243 C CE . MET C 1 444 ? 9.202 123.596 -8.207 1.00 13.14 ? 496 MET B CE 1 ATOM 7244 N N . ALA C 1 445 ? 9.491 119.637 -3.893 1.00 11.22 ? 497 ALA B N 1 ATOM 7245 C CA . ALA C 1 445 ? 8.748 118.781 -2.969 1.00 11.42 ? 497 ALA B CA 1 ATOM 7246 C C . ALA C 1 445 ? 7.272 119.152 -2.915 1.00 12.70 ? 497 ALA B C 1 ATOM 7247 O O . ALA C 1 445 ? 6.910 120.327 -2.799 1.00 13.78 ? 497 ALA B O 1 ATOM 7248 C CB . ALA C 1 445 ? 9.370 118.850 -1.584 1.00 12.93 ? 497 ALA B CB 1 ATOM 7249 N N . PHE C 1 446 ? 6.422 118.128 -3.006 1.00 11.30 ? 498 PHE B N 1 ATOM 7250 C CA . PHE C 1 446 ? 4.972 118.267 -3.008 1.00 12.48 ? 498 PHE B CA 1 ATOM 7251 C C . PHE C 1 446 ? 4.374 117.513 -1.830 1.00 10.87 ? 498 PHE B C 1 ATOM 7252 O O . PHE C 1 446 ? 4.942 116.510 -1.389 1.00 10.61 ? 498 PHE B O 1 ATOM 7253 C CB . PHE C 1 446 ? 4.355 117.690 -4.294 1.00 12.27 ? 498 PHE B CB 1 ATOM 7254 C CG . PHE C 1 446 ? 4.732 118.418 -5.548 1.00 12.28 ? 498 PHE B CG 1 ATOM 7255 C CD1 . PHE C 1 446 ? 5.877 118.077 -6.249 1.00 14.50 ? 498 PHE B CD1 1 ATOM 7256 C CD2 . PHE C 1 446 ? 3.921 119.422 -6.045 1.00 11.05 ? 498 PHE B CD2 1 ATOM 7257 C CE1 . PHE C 1 446 ? 6.215 118.740 -7.413 1.00 14.07 ? 498 PHE B CE1 1 ATOM 7258 C CE2 . PHE C 1 446 ? 4.251 120.090 -7.210 1.00 12.56 ? 498 PHE B CE2 1 ATOM 7259 C CZ . PHE C 1 446 ? 5.397 119.752 -7.896 1.00 12.52 ? 498 PHE B CZ 1 ATOM 7260 N N . THR C 1 447 ? 3.221 117.971 -1.354 1.00 10.22 ? 499 THR B N 1 ATOM 7261 C CA . THR C 1 447 ? 2.353 117.145 -0.521 1.00 9.70 ? 499 THR B CA 1 ATOM 7262 C C . THR C 1 447 ? 1.021 116.944 -1.217 1.00 10.01 ? 499 THR B C 1 ATOM 7263 O O . THR C 1 447 ? 0.687 117.622 -2.194 1.00 10.95 ? 499 THR B O 1 ATOM 7264 C CB . THR C 1 447 ? 2.063 117.741 0.874 1.00 11.91 ? 499 THR B CB 1 ATOM 7265 O OG1 . THR C 1 447 ? 1.012 118.711 0.780 1.00 11.31 ? 499 THR B OG1 1 ATOM 7266 C CG2 . THR C 1 447 ? 3.311 118.356 1.488 1.00 11.58 ? 499 THR B CG2 1 ATOM 7267 N N . SER C 1 448 ? 0.249 116.003 -0.690 1.00 11.35 ? 500 SER B N 1 ATOM 7268 C CA . SER C 1 448 ? -1.057 115.709 -1.251 1.00 10.66 ? 500 SER B CA 1 ATOM 7269 C C . SER C 1 448 ? -2.071 116.837 -1.044 1.00 10.86 ? 500 SER B C 1 ATOM 7270 O O . SER C 1 448 ? -3.147 116.823 -1.654 1.00 12.01 ? 500 SER B O 1 ATOM 7271 C CB . SER C 1 448 ? -1.590 114.412 -0.647 1.00 10.38 ? 500 SER B CB 1 ATOM 7272 O OG . SER C 1 448 ? -1.610 114.490 0.761 1.00 10.37 ? 500 SER B OG 1 ATOM 7273 N N . LEU C 1 449 ? -1.734 117.800 -0.186 1.00 10.44 ? 501 LEU B N 1 ATOM 7274 C CA . LEU C 1 449 ? -2.601 118.958 0.075 1.00 11.32 ? 501 LEU B CA 1 ATOM 7275 C C . LEU C 1 449 ? -2.112 120.227 -0.630 1.00 12.69 ? 501 LEU B C 1 ATOM 7276 O O . LEU C 1 449 ? -2.767 121.267 -0.552 1.00 11.88 ? 501 LEU B O 1 ATOM 7277 C CB . LEU C 1 449 ? -2.705 119.220 1.584 1.00 11.76 ? 501 LEU B CB 1 ATOM 7278 C CG . LEU C 1 449 ? -3.541 118.202 2.356 1.00 11.61 ? 501 LEU B CG 1 ATOM 7279 C CD1 . LEU C 1 449 ? -3.247 118.265 3.847 1.00 12.92 ? 501 LEU B CD1 1 ATOM 7280 C CD2 . LEU C 1 449 ? -5.035 118.402 2.098 1.00 11.79 ? 501 LEU B CD2 1 ATOM 7281 N N . SER C 1 450 ? -0.971 120.128 -1.305 1.00 11.08 ? 502 SER B N 1 ATOM 7282 C CA . SER C 1 450 ? -0.346 121.255 -2.006 1.00 11.86 ? 502 SER B CA 1 ATOM 7283 C C . SER C 1 450 ? -1.021 121.529 -3.332 1.00 13.42 ? 502 SER B C 1 ATOM 7284 O O . SER C 1 450 ? -1.541 120.619 -3.969 1.00 12.38 ? 502 SER B O 1 ATOM 7285 C CB . SER C 1 450 ? 1.132 120.973 -2.281 1.00 13.35 ? 502 SER B CB 1 ATOM 7286 O OG . SER C 1 450 ? 1.820 120.571 -1.119 1.00 13.12 ? 502 SER B OG 1 ATOM 7287 N N . ALA C 1 451 ? -0.975 122.779 -3.781 1.00 11.54 ? 503 ALA B N 1 ATOM 7288 C CA . ALA C 1 451 ? -1.245 123.065 -5.180 1.00 11.61 ? 503 ALA B CA 1 ATOM 7289 C C . ALA C 1 451 ? -0.138 122.441 -6.047 1.00 11.27 ? 503 ALA B C 1 ATOM 7290 O O . ALA C 1 451 ? 0.939 122.126 -5.541 1.00 12.79 ? 503 ALA B O 1 ATOM 7291 C CB . ALA C 1 451 ? -1.341 124.571 -5.408 1.00 13.66 ? 503 ALA B CB 1 ATOM 7292 N N . VAL C 1 452 ? -0.391 122.275 -7.346 1.00 12.38 ? 504 VAL B N 1 ATOM 7293 C CA . VAL C 1 452 ? 0.523 121.504 -8.190 1.00 11.47 ? 504 VAL B CA 1 ATOM 7294 C C . VAL C 1 452 ? 1.252 122.315 -9.270 1.00 12.33 ? 504 VAL B C 1 ATOM 7295 O O . VAL C 1 452 ? 1.875 121.735 -10.154 1.00 15.97 ? 504 VAL B O 1 ATOM 7296 C CB . VAL C 1 452 ? -0.229 120.322 -8.879 1.00 11.79 ? 504 VAL B CB 1 ATOM 7297 C CG1 . VAL C 1 452 ? -0.852 119.403 -7.826 1.00 15.79 ? 504 VAL B CG1 1 ATOM 7298 C CG2 . VAL C 1 452 ? -1.281 120.813 -9.856 1.00 12.48 ? 504 VAL B CG2 1 ATOM 7299 N N . ASP C 1 453 ? 1.185 123.644 -9.190 1.00 13.32 ? 505 ASP B N 1 ATOM 7300 C CA . ASP C 1 453 ? 1.898 124.518 -10.122 1.00 13.54 ? 505 ASP B CA 1 ATOM 7301 C C . ASP C 1 453 ? 3.356 124.702 -9.690 1.00 14.70 ? 505 ASP B C 1 ATOM 7302 O O . ASP C 1 453 ? 3.623 125.365 -8.689 1.00 12.87 ? 505 ASP B O 1 ATOM 7303 C CB . ASP C 1 453 ? 1.207 125.883 -10.201 1.00 14.29 ? 505 ASP B CB 1 ATOM 7304 C CG . ASP C 1 453 ? 1.775 126.772 -11.301 1.00 16.62 ? 505 ASP B CG 1 ATOM 7305 O OD1 . ASP C 1 453 ? 2.814 126.422 -11.900 1.00 15.39 ? 505 ASP B OD1 1 ATOM 7306 O OD2 . ASP C 1 453 ? 1.169 127.832 -11.569 1.00 18.26 ? 505 ASP B OD2 1 ATOM 7307 N N . PRO C 1 454 ? 4.310 124.139 -10.450 1.00 13.78 ? 506 PRO B N 1 ATOM 7308 C CA . PRO C 1 454 ? 5.704 124.313 -10.028 1.00 13.41 ? 506 PRO B CA 1 ATOM 7309 C C . PRO C 1 454 ? 6.181 125.768 -10.094 1.00 14.73 ? 506 PRO B C 1 ATOM 7310 O O . PRO C 1 454 ? 7.148 126.112 -9.409 1.00 14.54 ? 506 PRO B O 1 ATOM 7311 C CB . PRO C 1 454 ? 6.484 123.434 -11.015 1.00 14.98 ? 506 PRO B CB 1 ATOM 7312 C CG . PRO C 1 454 ? 5.586 123.317 -12.205 1.00 19.24 ? 506 PRO B CG 1 ATOM 7313 C CD . PRO C 1 454 ? 4.202 123.295 -11.658 1.00 14.87 ? 506 PRO B CD 1 ATOM 7314 N N . SER C 1 455 ? 5.502 126.610 -10.871 1.00 13.82 ? 507 SER B N 1 ATOM 7315 C CA A SER C 1 455 ? 5.946 127.985 -11.078 0.43 15.55 ? 507 SER B CA 1 ATOM 7316 C CA B SER C 1 455 ? 5.973 127.979 -11.073 0.57 15.51 ? 507 SER B CA 1 ATOM 7317 C C . SER C 1 455 ? 5.682 128.886 -9.876 1.00 17.24 ? 507 SER B C 1 ATOM 7318 O O . SER C 1 455 ? 6.199 130.007 -9.814 1.00 17.11 ? 507 SER B O 1 ATOM 7319 C CB A SER C 1 455 ? 5.269 128.579 -12.316 0.43 16.24 ? 507 SER B CB 1 ATOM 7320 C CB B SER C 1 455 ? 5.357 128.580 -12.344 0.57 16.21 ? 507 SER B CB 1 ATOM 7321 O OG A SER C 1 455 ? 5.702 127.919 -13.492 0.43 17.72 ? 507 SER B OG 1 ATOM 7322 O OG B SER C 1 455 ? 3.996 128.921 -12.159 0.57 17.33 ? 507 SER B OG 1 ATOM 7323 N N . ILE C 1 456 ? 4.873 128.416 -8.924 1.00 13.99 ? 508 ILE B N 1 ATOM 7324 C CA . ILE C 1 456 ? 4.597 129.200 -7.714 1.00 13.69 ? 508 ILE B CA 1 ATOM 7325 C C . ILE C 1 456 ? 5.382 128.694 -6.500 1.00 11.72 ? 508 ILE B C 1 ATOM 7326 O O . ILE C 1 456 ? 5.211 129.216 -5.397 1.00 13.71 ? 508 ILE B O 1 ATOM 7327 C CB . ILE C 1 456 ? 3.082 129.221 -7.359 1.00 14.43 ? 508 ILE B CB 1 ATOM 7328 C CG1 . ILE C 1 456 ? 2.580 127.853 -6.874 1.00 14.60 ? 508 ILE B CG1 1 ATOM 7329 C CG2 . ILE C 1 456 ? 2.284 129.705 -8.558 1.00 16.55 ? 508 ILE B CG2 1 ATOM 7330 C CD1 . ILE C 1 456 ? 1.132 127.849 -6.411 1.00 17.04 ? 508 ILE B CD1 1 ATOM 7331 N N . ALA C 1 457 ? 6.241 127.694 -6.699 1.00 12.66 ? 509 ALA B N 1 ATOM 7332 C CA . ALA C 1 457 ? 6.977 127.085 -5.595 1.00 11.27 ? 509 ALA B CA 1 ATOM 7333 C C . ALA C 1 457 ? 7.828 128.111 -4.843 1.00 15.13 ? 509 ALA B C 1 ATOM 7334 O O . ALA C 1 457 ? 8.381 129.035 -5.445 1.00 15.21 ? 509 ALA B O 1 ATOM 7335 C CB . ALA C 1 457 ? 7.854 125.953 -6.107 1.00 13.45 ? 509 ALA B CB 1 ATOM 7336 N N . ILE C 1 458 ? 7.936 127.931 -3.531 1.00 14.04 ? 510 ILE B N 1 ATOM 7337 C CA . ILE C 1 458 ? 8.744 128.824 -2.701 1.00 13.55 ? 510 ILE B CA 1 ATOM 7338 C C . ILE C 1 458 ? 9.634 128.006 -1.781 1.00 15.54 ? 510 ILE B C 1 ATOM 7339 O O . ILE C 1 458 ? 9.541 126.785 -1.753 1.00 13.70 ? 510 ILE B O 1 ATOM 7340 C CB . ILE C 1 458 ? 7.873 129.780 -1.873 1.00 21.52 ? 510 ILE B CB 1 ATOM 7341 C CG1 . ILE C 1 458 ? 6.933 129.001 -0.956 1.00 19.92 ? 510 ILE B CG1 1 ATOM 7342 C CG2 . ILE C 1 458 ? 7.087 130.702 -2.812 1.00 21.88 ? 510 ILE B CG2 1 ATOM 7343 C CD1 . ILE C 1 458 ? 6.118 129.888 -0.020 1.00 28.24 ? 510 ILE B CD1 1 ATOM 7344 N N . ASP C 1 459 ? 10.510 128.672 -1.040 1.00 13.45 ? 511 ASP B N 1 ATOM 7345 C CA . ASP C 1 459 ? 11.392 127.983 -0.105 1.00 12.73 ? 511 ASP B CA 1 ATOM 7346 C C . ASP C 1 459 ? 10.626 127.527 1.132 1.00 13.97 ? 511 ASP B C 1 ATOM 7347 O O . ASP C 1 459 ? 9.689 128.194 1.557 1.00 13.76 ? 511 ASP B O 1 ATOM 7348 C CB . ASP C 1 459 ? 12.530 128.892 0.348 1.00 14.60 ? 511 ASP B CB 1 ATOM 7349 C CG . ASP C 1 459 ? 13.424 129.317 -0.784 1.00 18.78 ? 511 ASP B CG 1 ATOM 7350 O OD1 . ASP C 1 459 ? 13.914 128.439 -1.523 1.00 17.53 ? 511 ASP B OD1 1 ATOM 7351 O OD2 . ASP C 1 459 ? 13.643 130.541 -0.929 1.00 20.93 ? 511 ASP B OD2 1 ATOM 7352 N N . PRO C 1 460 ? 11.050 126.410 1.738 1.00 13.93 ? 512 PRO B N 1 ATOM 7353 C CA . PRO C 1 460 ? 10.606 126.101 3.096 1.00 14.27 ? 512 PRO B CA 1 ATOM 7354 C C . PRO C 1 460 ? 11.291 127.026 4.088 1.00 14.84 ? 512 PRO B C 1 ATOM 7355 O O . PRO C 1 460 ? 12.204 127.756 3.708 1.00 16.57 ? 512 PRO B O 1 ATOM 7356 C CB . PRO C 1 460 ? 11.070 124.661 3.289 1.00 15.62 ? 512 PRO B CB 1 ATOM 7357 C CG . PRO C 1 460 ? 12.338 124.613 2.504 1.00 16.42 ? 512 PRO B CG 1 ATOM 7358 C CD . PRO C 1 460 ? 12.088 125.469 1.284 1.00 14.92 ? 512 PRO B CD 1 ATOM 7359 N N . ASP C 1 461 ? 10.865 127.001 5.341 1.00 13.71 ? 513 ASP B N 1 ATOM 7360 C CA . ASP C 1 461 ? 11.640 127.638 6.401 1.00 13.68 ? 513 ASP B CA 1 ATOM 7361 C C . ASP C 1 461 ? 12.993 126.925 6.490 1.00 15.18 ? 513 ASP B C 1 ATOM 7362 O O . ASP C 1 461 ? 13.053 125.692 6.504 1.00 14.22 ? 513 ASP B O 1 ATOM 7363 C CB . ASP C 1 461 ? 10.873 127.570 7.719 1.00 14.53 ? 513 ASP B CB 1 ATOM 7364 C CG . ASP C 1 461 ? 11.484 128.430 8.811 1.00 17.20 ? 513 ASP B CG 1 ATOM 7365 O OD1 . ASP C 1 461 ? 12.718 128.413 8.976 1.00 15.40 ? 513 ASP B OD1 1 ATOM 7366 O OD2 . ASP C 1 461 ? 10.705 129.111 9.516 1.00 23.39 ? 513 ASP B OD2 1 ATOM 7367 N N . SER C 1 462 ? 14.084 127.689 6.536 1.00 13.98 ? 514 SER B N 1 ATOM 7368 C CA . SER C 1 462 ? 15.415 127.096 6.543 1.00 13.26 ? 514 SER B CA 1 ATOM 7369 C C . SER C 1 462 ? 15.680 126.253 7.790 1.00 12.43 ? 514 SER B C 1 ATOM 7370 O O . SER C 1 462 ? 16.619 125.473 7.801 1.00 16.08 ? 514 SER B O 1 ATOM 7371 C CB . SER C 1 462 ? 16.496 128.174 6.419 1.00 17.35 ? 514 SER B CB 1 ATOM 7372 O OG . SER C 1 462 ? 16.493 129.012 7.553 1.00 19.72 ? 514 SER B OG 1 ATOM 7373 N N . ILE C 1 463 ? 14.867 126.405 8.830 1.00 14.28 ? 515 ILE B N 1 ATOM 7374 C CA . ILE C 1 463 ? 15.001 125.562 10.014 1.00 17.30 ? 515 ILE B CA 1 ATOM 7375 C C . ILE C 1 463 ? 14.882 124.091 9.623 1.00 17.97 ? 515 ILE B C 1 ATOM 7376 O O . ILE C 1 463 ? 15.457 123.223 10.270 1.00 19.80 ? 515 ILE B O 1 ATOM 7377 C CB . ILE C 1 463 ? 13.941 125.916 11.086 1.00 15.81 ? 515 ILE B CB 1 ATOM 7378 C CG1 . ILE C 1 463 ? 14.240 125.222 12.421 1.00 19.18 ? 515 ILE B CG1 1 ATOM 7379 C CG2 . ILE C 1 463 ? 12.529 125.550 10.631 1.00 18.28 ? 515 ILE B CG2 1 ATOM 7380 C CD1 . ILE C 1 463 ? 15.560 125.585 13.029 1.00 20.35 ? 515 ILE B CD1 1 ATOM 7381 N N . ALA C 1 464 ? 14.159 123.820 8.543 1.00 16.07 ? 516 ALA B N 1 ATOM 7382 C CA . ALA C 1 464 ? 13.907 122.439 8.136 1.00 16.94 ? 516 ALA B CA 1 ATOM 7383 C C . ALA C 1 464 ? 15.085 121.823 7.401 1.00 18.09 ? 516 ALA B C 1 ATOM 7384 O O . ALA C 1 464 ? 15.177 120.597 7.289 1.00 16.95 ? 516 ALA B O 1 ATOM 7385 C CB . ALA C 1 464 ? 12.667 122.373 7.258 1.00 17.43 ? 516 ALA B CB 1 ATOM 7386 N N . VAL C 1 465 ? 15.988 122.662 6.903 1.00 15.16 ? 517 VAL B N 1 ATOM 7387 C CA . VAL C 1 465 ? 17.010 122.215 5.973 1.00 14.32 ? 517 VAL B CA 1 ATOM 7388 C C . VAL C 1 465 ? 18.307 121.865 6.703 1.00 20.30 ? 517 VAL B C 1 ATOM 7389 O O . VAL C 1 465 ? 18.836 122.671 7.469 1.00 21.45 ? 517 VAL B O 1 ATOM 7390 C CB . VAL C 1 465 ? 17.272 123.294 4.898 1.00 17.61 ? 517 VAL B CB 1 ATOM 7391 C CG1 . VAL C 1 465 ? 18.329 122.838 3.911 1.00 20.59 ? 517 VAL B CG1 1 ATOM 7392 C CG2 . VAL C 1 465 ? 15.983 123.615 4.169 1.00 16.96 ? 517 VAL B CG2 1 ATOM 7393 N N . LEU C 1 466 ? 18.791 120.646 6.471 1.00 16.84 ? 518 LEU B N 1 ATOM 7394 C CA . LEU C 1 466 ? 20.070 120.177 6.995 1.00 19.12 ? 518 LEU B CA 1 ATOM 7395 C C . LEU C 1 466 ? 20.945 119.662 5.866 1.00 17.69 ? 518 LEU B C 1 ATOM 7396 O O . LEU C 1 466 ? 20.435 119.270 4.820 1.00 18.90 ? 518 LEU B O 1 ATOM 7397 C CB . LEU C 1 466 ? 19.865 119.059 8.016 1.00 16.87 ? 518 LEU B CB 1 ATOM 7398 C CG . LEU C 1 466 ? 19.144 119.431 9.305 1.00 19.46 ? 518 LEU B CG 1 ATOM 7399 C CD1 . LEU C 1 466 ? 18.763 118.188 10.083 1.00 21.35 ? 518 LEU B CD1 1 ATOM 7400 C CD2 . LEU C 1 466 ? 20.027 120.323 10.144 1.00 23.97 ? 518 LEU B CD2 1 ATOM 7401 N N . PRO C 1 467 ? 22.273 119.641 6.074 1.00 17.28 ? 519 PRO B N 1 ATOM 7402 C CA . PRO C 1 467 ? 23.154 119.040 5.073 1.00 15.86 ? 519 PRO B CA 1 ATOM 7403 C C . PRO C 1 467 ? 22.890 117.544 4.944 1.00 19.18 ? 519 PRO B C 1 ATOM 7404 O O . PRO C 1 467 ? 22.517 116.901 5.931 1.00 18.65 ? 519 PRO B O 1 ATOM 7405 C CB . PRO C 1 467 ? 24.562 119.314 5.623 1.00 20.22 ? 519 PRO B CB 1 ATOM 7406 C CG . PRO C 1 467 ? 24.372 119.536 7.066 1.00 24.25 ? 519 PRO B CG 1 ATOM 7407 C CD . PRO C 1 467 ? 23.020 120.144 7.238 1.00 20.86 ? 519 PRO B CD 1 ATOM 7408 N N . GLU C 1 468 ? 23.072 117.000 3.748 1.00 18.67 ? 520 GLU B N 1 ATOM 7409 C CA . GLU C 1 468 ? 22.793 115.591 3.526 1.00 21.55 ? 520 GLU B CA 1 ATOM 7410 C C . GLU C 1 468 ? 23.840 114.729 4.211 1.00 25.01 ? 520 GLU B C 1 ATOM 7411 O O . GLU C 1 468 ? 25.025 115.058 4.220 1.00 21.81 ? 520 GLU B O 1 ATOM 7412 C CB . GLU C 1 468 ? 22.745 115.251 2.033 1.00 22.35 ? 520 GLU B CB 1 ATOM 7413 C CG . GLU C 1 468 ? 22.452 113.770 1.789 1.00 21.51 ? 520 GLU B CG 1 ATOM 7414 C CD . GLU C 1 468 ? 22.307 113.398 0.328 1.00 28.70 ? 520 GLU B CD 1 ATOM 7415 O OE1 . GLU C 1 468 ? 22.379 114.291 -0.542 1.00 27.30 ? 520 GLU B OE1 1 ATOM 7416 O OE2 . GLU C 1 468 ? 22.122 112.191 0.052 1.00 28.93 ? 520 GLU B OE2 1 ATOM 7417 N N . ASP C 1 469 ? 23.386 113.624 4.789 1.00 22.81 ? 521 ASP B N 1 ATOM 7418 C CA . ASP C 1 469 ? 24.285 112.580 5.256 1.00 23.93 ? 521 ASP B CA 1 ATOM 7419 C C . ASP C 1 469 ? 24.721 111.752 4.050 1.00 26.79 ? 521 ASP B C 1 ATOM 7420 O O . ASP C 1 469 ? 24.023 110.834 3.636 1.00 26.52 ? 521 ASP B O 1 ATOM 7421 C CB . ASP C 1 469 ? 23.591 111.712 6.305 1.00 23.82 ? 521 ASP B CB 1 ATOM 7422 C CG . ASP C 1 469 ? 24.481 110.603 6.833 1.00 32.20 ? 521 ASP B CG 1 ATOM 7423 O OD1 . ASP C 1 469 ? 25.661 110.520 6.426 1.00 29.47 ? 521 ASP B OD1 1 ATOM 7424 O OD2 . ASP C 1 469 ? 23.993 109.818 7.669 1.00 30.81 ? 521 ASP B OD2 1 ATOM 7425 N N . LYS C 1 470 ? 25.874 112.087 3.483 1.00 29.35 ? 522 LYS B N 1 ATOM 7426 C CA . LYS C 1 470 ? 26.336 111.426 2.268 1.00 31.88 ? 522 LYS B CA 1 ATOM 7427 C C . LYS C 1 470 ? 27.050 110.104 2.560 1.00 38.85 ? 522 LYS B C 1 ATOM 7428 O O . LYS C 1 470 ? 27.608 109.484 1.655 1.00 41.51 ? 522 LYS B O 1 ATOM 7429 C CB . LYS C 1 470 ? 27.251 112.368 1.486 1.00 29.13 ? 522 LYS B CB 1 ATOM 7430 C CG . LYS C 1 470 ? 26.516 113.569 0.917 1.00 35.22 ? 522 LYS B CG 1 ATOM 7431 C CD . LYS C 1 470 ? 27.468 114.578 0.311 1.00 41.03 ? 522 LYS B CD 1 ATOM 7432 C CE . LYS C 1 470 ? 26.742 115.860 -0.057 1.00 39.15 ? 522 LYS B CE 1 ATOM 7433 N NZ . LYS C 1 470 ? 27.571 116.751 -0.912 1.00 49.57 ? 522 LYS B NZ 1 ATOM 7434 N N . CYS C 1 471 ? 27.010 109.669 3.818 1.00 32.49 ? 523 CYS B N 1 ATOM 7435 C CA . CYS C 1 471 ? 27.659 108.422 4.222 1.00 37.54 ? 523 CYS B CA 1 ATOM 7436 C C . CYS C 1 471 ? 26.674 107.258 4.327 1.00 43.48 ? 523 CYS B C 1 ATOM 7437 O O . CYS C 1 471 ? 27.070 106.130 4.627 1.00 42.37 ? 523 CYS B O 1 ATOM 7438 C CB . CYS C 1 471 ? 28.376 108.608 5.559 1.00 38.73 ? 523 CYS B CB 1 ATOM 7439 S SG . CYS C 1 471 ? 29.781 109.742 5.487 1.00 51.40 ? 523 CYS B SG 1 ATOM 7440 N N . VAL C 1 472 ? 25.395 107.531 4.086 1.00 35.81 ? 524 VAL B N 1 ATOM 7441 C CA . VAL C 1 472 ? 24.386 106.478 4.063 1.00 39.35 ? 524 VAL B CA 1 ATOM 7442 C C . VAL C 1 472 ? 24.623 105.566 2.862 1.00 42.66 ? 524 VAL B C 1 ATOM 7443 O O . VAL C 1 472 ? 24.479 104.349 2.958 1.00 48.15 ? 524 VAL B O 1 ATOM 7444 C CB . VAL C 1 472 ? 22.951 107.057 4.005 1.00 41.35 ? 524 VAL B CB 1 ATOM 7445 C CG1 . VAL C 1 472 ? 21.916 105.946 3.820 1.00 37.41 ? 524 VAL B CG1 1 ATOM 7446 C CG2 . VAL C 1 472 ? 22.651 107.854 5.267 1.00 36.96 ? 524 VAL B CG2 1 ATOM 7447 N N . VAL D 2 7 ? -41.467 116.046 10.469 1.00 42.90 ? 1294 VAL D N 1 ATOM 7448 C CA . VAL D 2 7 ? -40.411 116.893 11.012 1.00 33.72 ? 1294 VAL D CA 1 ATOM 7449 C C . VAL D 2 7 ? -39.987 117.940 9.996 1.00 30.79 ? 1294 VAL D C 1 ATOM 7450 O O . VAL D 2 7 ? -39.887 117.662 8.800 1.00 32.45 ? 1294 VAL D O 1 ATOM 7451 C CB . VAL D 2 7 ? -39.172 116.061 11.438 1.00 35.81 ? 1294 VAL D CB 1 ATOM 7452 C CG1 . VAL D 2 7 ? -38.018 116.967 11.889 1.00 36.01 ? 1294 VAL D CG1 1 ATOM 7453 C CG2 . VAL D 2 7 ? -39.548 115.101 12.545 1.00 39.27 ? 1294 VAL D CG2 1 ATOM 7454 N N . GLN D 2 8 ? -39.749 119.150 10.485 1.00 26.64 ? 1295 GLN D N 1 ATOM 7455 C CA . GLN D 2 8 ? -39.138 120.193 9.681 1.00 29.33 ? 1295 GLN D CA 1 ATOM 7456 C C . GLN D 2 8 ? -38.463 121.193 10.610 1.00 26.84 ? 1295 GLN D C 1 ATOM 7457 O O . GLN D 2 8 ? -38.859 121.337 11.767 1.00 28.32 ? 1295 GLN D O 1 ATOM 7458 C CB . GLN D 2 8 ? -40.176 120.873 8.786 1.00 35.11 ? 1295 GLN D CB 1 ATOM 7459 C CG . GLN D 2 8 ? -41.182 121.708 9.530 1.00 29.70 ? 1295 GLN D CG 1 ATOM 7460 C CD . GLN D 2 8 ? -42.413 122.026 8.699 1.00 38.08 ? 1295 GLN D CD 1 ATOM 7461 O OE1 . GLN D 2 8 ? -43.531 121.663 9.064 1.00 38.58 ? 1295 GLN D OE1 1 ATOM 7462 N NE2 . GLN D 2 8 ? -42.214 122.711 7.580 1.00 33.11 ? 1295 GLN D NE2 1 ATOM 7463 N N . ASN D 2 9 ? -37.415 121.852 10.125 1.00 23.65 ? 1296 ASN D N 1 ATOM 7464 C CA . ASN D 2 9 ? -36.698 122.814 10.946 1.00 21.39 ? 1296 ASN D CA 1 ATOM 7465 C C . ASN D 2 9 ? -37.402 124.165 10.910 1.00 23.48 ? 1296 ASN D C 1 ATOM 7466 O O . ASN D 2 9 ? -38.438 124.307 10.258 1.00 22.86 ? 1296 ASN D O 1 ATOM 7467 C CB . ASN D 2 9 ? -35.220 122.920 10.516 1.00 22.68 ? 1296 ASN D CB 1 ATOM 7468 C CG . ASN D 2 9 ? -35.020 123.568 9.149 1.00 25.42 ? 1296 ASN D CG 1 ATOM 7469 O OD1 . ASN D 2 9 ? -35.965 123.806 8.400 1.00 22.61 ? 1296 ASN D OD1 1 ATOM 7470 N ND2 . ASN D 2 9 ? -33.760 123.836 8.817 1.00 25.49 ? 1296 ASN D ND2 1 ATOM 7471 N N . GLN D 2 10 ? -36.855 125.136 11.632 1.00 22.61 ? 1297 GLN D N 1 ATOM 7472 C CA . GLN D 2 10 ? -37.520 126.421 11.820 1.00 24.86 ? 1297 GLN D CA 1 ATOM 7473 C C . GLN D 2 10 ? -37.579 127.213 10.520 1.00 28.10 ? 1297 GLN D C 1 ATOM 7474 O O . GLN D 2 10 ? -38.571 127.890 10.249 1.00 26.97 ? 1297 GLN D O 1 ATOM 7475 C CB . GLN D 2 10 ? -36.814 127.230 12.908 1.00 27.35 ? 1297 GLN D CB 1 ATOM 7476 C CG . GLN D 2 10 ? -36.989 126.648 14.309 1.00 30.16 ? 1297 GLN D CG 1 ATOM 7477 C CD . GLN D 2 10 ? -38.444 126.626 14.757 1.00 35.97 ? 1297 GLN D CD 1 ATOM 7478 O OE1 . GLN D 2 10 ? -39.241 127.477 14.364 1.00 32.48 ? 1297 GLN D OE1 1 ATOM 7479 N NE2 . GLN D 2 10 ? -38.796 125.641 15.570 1.00 34.89 ? 1297 GLN D NE2 1 ATOM 7480 N N . SER D 2 11 ? -36.526 127.130 9.712 1.00 24.08 ? 1298 SER D N 1 ATOM 7481 C CA . SER D 2 11 ? -36.522 127.835 8.434 1.00 21.46 ? 1298 SER D CA 1 ATOM 7482 C C . SER D 2 11 ? -37.540 127.232 7.472 1.00 20.11 ? 1298 SER D C 1 ATOM 7483 O O . SER D 2 11 ? -38.072 127.935 6.615 1.00 26.33 ? 1298 SER D O 1 ATOM 7484 C CB . SER D 2 11 ? -35.119 127.824 7.821 1.00 23.16 ? 1298 SER D CB 1 ATOM 7485 O OG . SER D 2 11 ? -34.305 128.790 8.458 1.00 22.97 ? 1298 SER D OG 1 ATOM 7486 N N . SER D 2 12 ? -37.837 125.945 7.618 1.00 21.23 ? 1299 SER D N 1 ATOM 7487 C CA . SER D 2 12 ? -38.896 125.324 6.828 1.00 20.47 ? 1299 SER D CA 1 ATOM 7488 C C . SER D 2 12 ? -40.268 125.780 7.316 1.00 27.76 ? 1299 SER D C 1 ATOM 7489 O O . SER D 2 12 ? -41.193 125.936 6.522 1.00 27.24 ? 1299 SER D O 1 ATOM 7490 C CB . SER D 2 12 ? -38.812 123.803 6.892 1.00 22.80 ? 1299 SER D CB 1 ATOM 7491 O OG . SER D 2 12 ? -39.901 123.214 6.207 1.00 22.55 ? 1299 SER D OG 1 ATOM 7492 N N . LEU D 2 13 ? -40.388 125.975 8.626 1.00 26.88 ? 1300 LEU D N 1 ATOM 7493 C CA . LEU D 2 13 ? -41.636 126.433 9.235 1.00 30.88 ? 1300 LEU D CA 1 ATOM 7494 C C . LEU D 2 13 ? -41.914 127.895 8.932 1.00 30.47 ? 1300 LEU D C 1 ATOM 7495 O O . LEU D 2 13 ? -43.069 128.320 8.884 1.00 31.55 ? 1300 LEU D O 1 ATOM 7496 C CB . LEU D 2 13 ? -41.593 126.253 10.755 1.00 27.33 ? 1300 LEU D CB 1 ATOM 7497 C CG . LEU D 2 13 ? -41.736 124.841 11.306 1.00 31.77 ? 1300 LEU D CG 1 ATOM 7498 C CD1 . LEU D 2 13 ? -41.444 124.833 12.800 1.00 37.05 ? 1300 LEU D CD1 1 ATOM 7499 C CD2 . LEU D 2 13 ? -43.125 124.299 11.028 1.00 41.33 ? 1300 LEU D CD2 1 ATOM 7500 N N . ALA D 2 14 ? -40.844 128.658 8.743 1.00 27.19 ? 1301 ALA D N 1 ATOM 7501 C CA . ALA D 2 14 ? -40.913 130.114 8.685 1.00 27.99 ? 1301 ALA D CA 1 ATOM 7502 C C . ALA D 2 14 ? -41.925 130.677 7.677 1.00 32.81 ? 1301 ALA D C 1 ATOM 7503 O O . ALA D 2 14 ? -42.670 131.594 8.018 1.00 28.25 ? 1301 ALA D O 1 ATOM 7504 C CB . ALA D 2 14 ? -39.533 130.674 8.396 1.00 28.85 ? 1301 ALA D CB 1 ATOM 7505 N N . PRO D 2 15 ? -41.957 130.150 6.439 1.00 27.21 ? 1302 PRO D N 1 ATOM 7506 C CA . PRO D 2 15 ? -42.911 130.718 5.473 1.00 31.22 ? 1302 PRO D CA 1 ATOM 7507 C C . PRO D 2 15 ? -44.361 130.650 5.945 1.00 29.20 ? 1302 PRO D C 1 ATOM 7508 O O . PRO D 2 15 ? -45.118 131.597 5.753 1.00 36.48 ? 1302 PRO D O 1 ATOM 7509 C CB . PRO D 2 15 ? -42.714 129.849 4.228 1.00 35.00 ? 1302 PRO D CB 1 ATOM 7510 C CG . PRO D 2 15 ? -41.345 129.303 4.363 1.00 28.41 ? 1302 PRO D CG 1 ATOM 7511 C CD . PRO D 2 15 ? -41.137 129.090 5.828 1.00 24.08 ? 1302 PRO D CD 1 ATOM 7512 N N . GLU D 2 16 ? -44.726 129.542 6.574 1.00 31.81 ? 1303 GLU D N 1 ATOM 7513 C CA . GLU D 2 16 ? -46.111 129.296 6.956 1.00 32.34 ? 1303 GLU D CA 1 ATOM 7514 C C . GLU D 2 16 ? -46.533 130.161 8.146 1.00 33.63 ? 1303 GLU D C 1 ATOM 7515 O O . GLU D 2 16 ? -47.720 130.260 8.457 1.00 42.63 ? 1303 GLU D O 1 ATOM 7516 C CB . GLU D 2 16 ? -46.308 127.816 7.284 1.00 40.08 ? 1303 GLU D CB 1 ATOM 7517 C CG . GLU D 2 16 ? -45.546 126.868 6.356 1.00 42.83 ? 1303 GLU D CG 1 ATOM 7518 C CD . GLU D 2 16 ? -45.911 127.077 4.904 1.00 42.38 ? 1303 GLU D CD 1 ATOM 7519 O OE1 . GLU D 2 16 ? -47.110 127.281 4.623 1.00 42.92 ? 1303 GLU D OE1 1 ATOM 7520 O OE2 . GLU D 2 16 ? -45.005 127.046 4.045 1.00 46.76 ? 1303 GLU D OE2 1 ATOM 7521 N N . LEU D 2 17 ? -45.560 130.788 8.801 1.00 27.84 ? 1304 LEU D N 1 ATOM 7522 C CA . LEU D 2 17 ? -45.826 131.635 9.964 1.00 32.47 ? 1304 LEU D CA 1 ATOM 7523 C C . LEU D 2 17 ? -45.628 133.108 9.635 1.00 34.52 ? 1304 LEU D C 1 ATOM 7524 O O . LEU D 2 17 ? -45.923 133.984 10.451 1.00 36.02 ? 1304 LEU D O 1 ATOM 7525 C CB . LEU D 2 17 ? -44.920 131.240 11.130 1.00 33.39 ? 1304 LEU D CB 1 ATOM 7526 C CG . LEU D 2 17 ? -45.026 129.786 11.604 1.00 33.19 ? 1304 LEU D CG 1 ATOM 7527 C CD1 . LEU D 2 17 ? -44.011 129.513 12.705 1.00 40.70 ? 1304 LEU D CD1 1 ATOM 7528 C CD2 . LEU D 2 17 ? -46.438 129.467 12.088 1.00 37.54 ? 1304 LEU D CD2 1 ATOM 7529 N N . SER D 2 18 ? -45.127 133.378 8.434 1.00 30.31 ? 1305 SER D N 1 ATOM 7530 C CA . SER D 2 18 ? -44.849 134.740 8.007 1.00 26.97 ? 1305 SER D CA 1 ATOM 7531 C C . SER D 2 18 ? -46.128 135.520 7.749 1.00 21.46 ? 1305 SER D C 1 ATOM 7532 O O . SER D 2 18 ? -47.153 134.950 7.375 1.00 23.49 ? 1305 SER D O 1 ATOM 7533 C CB . SER D 2 18 ? -43.990 134.738 6.740 1.00 26.82 ? 1305 SER D CB 1 ATOM 7534 O OG . SER D 2 18 ? -43.659 136.055 6.339 1.00 26.05 ? 1305 SER D OG 1 ATOM 7535 N N . GLY D 2 19 ? -46.044 136.828 7.943 1.00 25.61 ? 1306 GLY D N 1 ATOM 7536 C CA . GLY D 2 19 ? -47.107 137.726 7.540 1.00 28.97 ? 1306 GLY D CA 1 ATOM 7537 C C . GLY D 2 19 ? -47.185 137.815 6.029 1.00 27.26 ? 1306 GLY D C 1 ATOM 7538 O O . GLY D 2 19 ? -48.222 138.170 5.473 1.00 25.35 ? 1306 GLY D O 1 ATOM 7539 N N . CYS D 2 20 ? -46.081 137.482 5.364 1.00 23.06 ? 1307 CYS D N 1 ATOM 7540 C CA . CYS D 2 20 ? -46.006 137.551 3.911 1.00 22.28 ? 1307 CYS D CA 1 ATOM 7541 C C . CYS D 2 20 ? -45.240 136.370 3.325 1.00 21.28 ? 1307 CYS D C 1 ATOM 7542 O O . CYS D 2 20 ? -44.116 136.535 2.850 1.00 22.11 ? 1307 CYS D O 1 ATOM 7543 C CB . CYS D 2 20 ? -45.344 138.857 3.475 1.00 25.73 ? 1307 CYS D CB 1 ATOM 7544 S SG . CYS D 2 20 ? -46.401 140.314 3.679 1.00 31.24 ? 1307 CYS D SG 1 ATOM 7545 N N . PRO D 2 21 ? -45.848 135.175 3.353 1.00 25.86 ? 1308 PRO D N 1 ATOM 7546 C CA . PRO D 2 21 ? -45.251 134.040 2.643 1.00 25.06 ? 1308 PRO D CA 1 ATOM 7547 C C . PRO D 2 21 ? -45.209 134.303 1.144 1.00 26.43 ? 1308 PRO D C 1 ATOM 7548 O O . PRO D 2 21 ? -45.956 135.157 0.661 1.00 22.55 ? 1308 PRO D O 1 ATOM 7549 C CB . PRO D 2 21 ? -46.187 132.877 2.972 1.00 25.10 ? 1308 PRO D CB 1 ATOM 7550 C CG . PRO D 2 21 ? -47.466 133.507 3.376 1.00 34.31 ? 1308 PRO D CG 1 ATOM 7551 C CD . PRO D 2 21 ? -47.113 134.813 4.010 1.00 26.12 ? 1308 PRO D CD 1 ATOM 7552 N N . PRO D 2 22 ? -44.373 133.562 0.404 1.00 20.87 ? 1309 PRO D N 1 ATOM 7553 C CA . PRO D 2 22 ? -43.493 132.491 0.895 1.00 24.51 ? 1309 PRO D CA 1 ATOM 7554 C C . PRO D 2 22 ? -42.063 132.915 1.266 1.00 28.68 ? 1309 PRO D C 1 ATOM 7555 O O . PRO D 2 22 ? -41.320 132.071 1.777 1.00 28.83 ? 1309 PRO D O 1 ATOM 7556 C CB . PRO D 2 22 ? -43.467 131.520 -0.285 1.00 24.28 ? 1309 PRO D CB 1 ATOM 7557 C CG . PRO D 2 22 ? -43.600 132.402 -1.487 1.00 25.42 ? 1309 PRO D CG 1 ATOM 7558 C CD . PRO D 2 22 ? -44.504 133.539 -1.064 1.00 25.27 ? 1309 PRO D CD 1 ATOM 7559 N N . MET D 2 23 ? -41.681 134.170 1.021 1.00 19.33 ? 1310 MET D N 1 ATOM 7560 C CA . MET D 2 23 ? -40.304 134.626 1.254 1.00 23.15 ? 1310 MET D CA 1 ATOM 7561 C C . MET D 2 23 ? -40.179 135.712 2.308 1.00 23.87 ? 1310 MET D C 1 ATOM 7562 O O . MET D 2 23 ? -39.078 136.022 2.751 1.00 25.92 ? 1310 MET D O 1 ATOM 7563 C CB . MET D 2 23 ? -39.691 135.171 -0.036 1.00 30.31 ? 1310 MET D CB 1 ATOM 7564 C CG . MET D 2 23 ? -39.611 134.197 -1.171 1.00 36.96 ? 1310 MET D CG 1 ATOM 7565 S SD . MET D 2 23 ? -37.937 134.136 -1.819 1.00 63.72 ? 1310 MET D SD 1 ATOM 7566 C CE . MET D 2 23 ? -37.181 133.131 -0.549 1.00 21.69 ? 1310 MET D CE 1 ATOM 7567 N N . GLY D 2 24 ? -41.304 136.321 2.671 1.00 22.11 ? 1311 GLY D N 1 ATOM 7568 C CA . GLY D 2 24 ? -41.311 137.427 3.609 1.00 21.34 ? 1311 GLY D CA 1 ATOM 7569 C C . GLY D 2 24 ? -41.661 138.741 2.929 1.00 22.82 ? 1311 GLY D C 1 ATOM 7570 O O . GLY D 2 24 ? -41.626 139.799 3.555 1.00 24.65 ? 1311 GLY D O 1 ATOM 7571 N N . ILE D 2 25 ? -41.997 138.666 1.644 1.00 19.20 ? 1312 ILE D N 1 ATOM 7572 C CA . ILE D 2 25 ? -42.363 139.855 0.875 1.00 21.26 ? 1312 ILE D CA 1 ATOM 7573 C C . ILE D 2 25 ? -43.781 139.685 0.343 1.00 20.31 ? 1312 ILE D C 1 ATOM 7574 O O . ILE D 2 25 ? -44.123 138.651 -0.229 1.00 19.09 ? 1312 ILE D O 1 ATOM 7575 C CB . ILE D 2 25 ? -41.364 140.114 -0.268 1.00 20.78 ? 1312 ILE D CB 1 ATOM 7576 C CG1 . ILE D 2 25 ? -40.004 140.490 0.334 1.00 23.16 ? 1312 ILE D CG1 1 ATOM 7577 C CG2 . ILE D 2 25 ? -41.867 141.229 -1.191 1.00 24.53 ? 1312 ILE D CG2 1 ATOM 7578 C CD1 . ILE D 2 25 ? -38.915 140.756 -0.660 1.00 29.46 ? 1312 ILE D CD1 1 ATOM 7579 N N . CYS D 2 26 ? -44.607 140.709 0.553 1.00 22.33 ? 1313 CYS D N 1 ATOM 7580 C CA . CYS D 2 26 ? -46.023 140.650 0.201 1.00 23.22 ? 1313 CYS D CA 1 ATOM 7581 C C . CYS D 2 26 ? -46.220 140.770 -1.309 1.00 23.01 ? 1313 CYS D C 1 ATOM 7582 O O . CYS D 2 26 ? -45.291 141.114 -2.032 1.00 23.37 ? 1313 CYS D O 1 ATOM 7583 C CB . CYS D 2 26 ? -46.788 141.752 0.928 1.00 25.77 ? 1313 CYS D CB 1 ATOM 7584 S SG . CYS D 2 26 ? -46.203 142.032 2.615 1.00 44.12 ? 1313 CYS D SG 1 ATOM 7585 N N . MET D 2 27 ? -47.432 140.512 -1.786 1.00 24.14 ? 1314 MET D N 1 ATOM 7586 C CA A MET D 2 27 ? -47.681 140.401 -3.224 0.46 27.94 ? 1314 MET D CA 1 ATOM 7587 C CA B MET D 2 27 ? -47.639 140.389 -3.223 0.54 27.94 ? 1314 MET D CA 1 ATOM 7588 C C . MET D 2 27 ? -47.356 141.679 -3.990 1.00 30.41 ? 1314 MET D C 1 ATOM 7589 O O . MET D 2 27 ? -46.982 141.627 -5.160 1.00 29.21 ? 1314 MET D O 1 ATOM 7590 C CB A MET D 2 27 ? -49.138 140.003 -3.500 0.46 30.43 ? 1314 MET D CB 1 ATOM 7591 C CB B MET D 2 27 ? -49.057 139.912 -3.524 0.54 30.37 ? 1314 MET D CB 1 ATOM 7592 C CG A MET D 2 27 ? -49.480 140.051 -4.990 0.46 31.50 ? 1314 MET D CG 1 ATOM 7593 C CG B MET D 2 27 ? -50.171 140.853 -3.102 0.54 30.60 ? 1314 MET D CG 1 ATOM 7594 S SD A MET D 2 27 ? -50.591 138.774 -5.605 0.46 47.56 ? 1314 MET D SD 1 ATOM 7595 S SD B MET D 2 27 ? -51.808 140.219 -3.545 0.54 41.80 ? 1314 MET D SD 1 ATOM 7596 C CE A MET D 2 27 ? -52.172 139.371 -5.021 0.46 39.92 ? 1314 MET D CE 1 ATOM 7597 C CE B MET D 2 27 ? -51.528 139.556 -5.196 0.54 38.53 ? 1314 MET D CE 1 ATOM 7598 N N . ASP D 2 28 ? -47.502 142.828 -3.341 1.00 26.58 ? 1315 ASP D N 1 ATOM 7599 C CA . ASP D 2 28 ? -47.208 144.092 -4.019 1.00 26.00 ? 1315 ASP D CA 1 ATOM 7600 C C . ASP D 2 28 ? -45.735 144.474 -3.884 1.00 40.03 ? 1315 ASP D C 1 ATOM 7601 O O . ASP D 2 28 ? -45.309 145.514 -4.389 1.00 34.13 ? 1315 ASP D O 1 ATOM 7602 C CB . ASP D 2 28 ? -48.096 145.211 -3.474 1.00 31.92 ? 1315 ASP D CB 1 ATOM 7603 C CG . ASP D 2 28 ? -47.759 145.577 -2.050 1.00 38.33 ? 1315 ASP D CG 1 ATOM 7604 O OD1 . ASP D 2 28 ? -47.203 144.718 -1.334 1.00 39.45 ? 1315 ASP D OD1 1 ATOM 7605 O OD2 . ASP D 2 28 ? -48.059 146.720 -1.645 1.00 40.85 ? 1315 ASP D OD2 1 ATOM 7606 N N . GLY D 2 29 ? -44.966 143.631 -3.198 1.00 36.00 ? 1316 GLY D N 1 ATOM 7607 C CA . GLY D 2 29 ? -43.535 143.836 -3.074 1.00 30.67 ? 1316 GLY D CA 1 ATOM 7608 C C . GLY D 2 29 ? -43.136 144.367 -1.711 1.00 34.31 ? 1316 GLY D C 1 ATOM 7609 O O . GLY D 2 29 ? -41.963 144.339 -1.356 1.00 43.01 ? 1316 GLY D O 1 ATOM 7610 N N . THR D 2 30 ? -44.106 144.835 -0.933 1.00 30.47 ? 1317 THR D N 1 ATOM 7611 C CA . THR D 2 30 ? -43.812 145.405 0.377 1.00 33.78 ? 1317 THR D CA 1 ATOM 7612 C C . THR D 2 30 ? -43.387 144.333 1.390 1.00 43.79 ? 1317 THR D C 1 ATOM 7613 O O . THR D 2 30 ? -43.583 143.135 1.177 1.00 32.47 ? 1317 THR D O 1 ATOM 7614 C CB . THR D 2 30 ? -45.024 146.173 0.939 1.00 40.58 ? 1317 THR D CB 1 ATOM 7615 O OG1 . THR D 2 30 ? -46.121 145.272 1.132 1.00 43.87 ? 1317 THR D OG1 1 ATOM 7616 C CG2 . THR D 2 30 ? -45.440 147.298 -0.012 1.00 42.01 ? 1317 THR D CG2 1 ATOM 7617 N N . ILE D 2 31 ? -42.820 144.785 2.503 1.00 44.36 ? 1318 ILE D N 1 ATOM 7618 C CA . ILE D 2 31 ? -42.158 143.895 3.454 1.00 35.92 ? 1318 ILE D CA 1 ATOM 7619 C C . ILE D 2 31 ? -43.077 143.593 4.626 1.00 37.06 ? 1318 ILE D C 1 ATOM 7620 O O . ILE D 2 31 ? -43.696 144.498 5.186 1.00 47.20 ? 1318 ILE D O 1 ATOM 7621 C CB . ILE D 2 31 ? -40.850 144.517 3.962 1.00 31.22 ? 1318 ILE D CB 1 ATOM 7622 C CG1 . ILE D 2 31 ? -40.022 145.018 2.779 1.00 38.85 ? 1318 ILE D CG1 1 ATOM 7623 C CG2 . ILE D 2 31 ? -40.045 143.505 4.775 1.00 37.56 ? 1318 ILE D CG2 1 ATOM 7624 C CD1 . ILE D 2 31 ? -39.296 146.276 3.069 1.00 51.00 ? 1318 ILE D CD1 1 ATOM 7625 N N . GLY D 2 32 ? -43.158 142.317 4.993 1.00 33.77 ? 1319 GLY D N 1 ATOM 7626 C CA . GLY D 2 32 ? -44.087 141.863 6.011 1.00 35.90 ? 1319 GLY D CA 1 ATOM 7627 C C . GLY D 2 32 ? -43.416 141.507 7.323 1.00 39.19 ? 1319 GLY D C 1 ATOM 7628 O O . GLY D 2 32 ? -42.192 141.574 7.439 1.00 38.45 ? 1319 GLY D O 1 ATOM 7629 N N . ASP D 2 33 ? -44.222 141.126 8.312 1.00 39.19 ? 1320 ASP D N 1 ATOM 7630 C CA . ASP D 2 33 ? -43.703 140.762 9.628 1.00 40.80 ? 1320 ASP D CA 1 ATOM 7631 C C . ASP D 2 33 ? -43.364 139.267 9.697 1.00 30.39 ? 1320 ASP D C 1 ATOM 7632 O O . ASP D 2 33 ? -44.132 138.438 9.207 1.00 35.66 ? 1320 ASP D O 1 ATOM 7633 C CB . ASP D 2 33 ? -44.709 141.110 10.724 1.00 39.92 ? 1320 ASP D CB 1 ATOM 7634 C CG . ASP D 2 33 ? -45.177 142.548 10.651 1.00 54.87 ? 1320 ASP D CG 1 ATOM 7635 O OD1 . ASP D 2 33 ? -44.566 143.342 9.901 1.00 59.39 ? 1320 ASP D OD1 1 ATOM 7636 O OD2 . ASP D 2 33 ? -46.154 142.886 11.353 1.00 57.53 ? 1320 ASP D OD2 1 ATOM 7637 N N . PRO D 2 34 ? -42.222 138.919 10.321 1.00 37.28 ? 1321 PRO D N 1 ATOM 7638 C CA . PRO D 2 34 ? -41.749 137.527 10.395 1.00 34.26 ? 1321 PRO D CA 1 ATOM 7639 C C . PRO D 2 34 ? -42.737 136.522 10.988 1.00 30.17 ? 1321 PRO D C 1 ATOM 7640 O O . PRO D 2 34 ? -42.838 135.405 10.482 1.00 32.12 ? 1321 PRO D O 1 ATOM 7641 C CB . PRO D 2 34 ? -40.514 137.632 11.295 1.00 39.14 ? 1321 PRO D CB 1 ATOM 7642 C CG . PRO D 2 34 ? -40.014 138.998 11.076 1.00 40.32 ? 1321 PRO D CG 1 ATOM 7643 C CD . PRO D 2 34 ? -41.236 139.851 10.898 1.00 40.79 ? 1321 PRO D CD 1 ATOM 7644 N N . ILE D 2 35 ? -43.438 136.901 12.053 1.00 35.24 ? 1322 ILE D N 1 ATOM 7645 C CA . ILE D 2 35 ? -44.403 136.003 12.676 1.00 33.54 ? 1322 ILE D CA 1 ATOM 7646 C C . ILE D 2 35 ? -45.746 136.718 12.786 1.00 35.08 ? 1322 ILE D C 1 ATOM 7647 O O . ILE D 2 35 ? -45.902 137.669 13.550 1.00 40.16 ? 1322 ILE D O 1 ATOM 7648 C CB . ILE D 2 35 ? -43.911 135.518 14.056 1.00 41.06 ? 1322 ILE D CB 1 ATOM 7649 C CG1 . ILE D 2 35 ? -42.583 134.763 13.895 1.00 36.22 ? 1322 ILE D CG1 1 ATOM 7650 C CG2 . ILE D 2 35 ? -44.952 134.620 14.700 1.00 41.80 ? 1322 ILE D CG2 1 ATOM 7651 C CD1 . ILE D 2 35 ? -41.952 134.294 15.201 1.00 41.62 ? 1322 ILE D CD1 1 ATOM 7652 N N . ALA D 2 36 ? -46.706 136.248 11.997 1.00 33.44 ? 1323 ALA D N 1 ATOM 7653 C CA . ALA D 2 36 ? -47.995 136.917 11.857 1.00 35.32 ? 1323 ALA D CA 1 ATOM 7654 C C . ALA D 2 36 ? -48.912 136.691 13.053 1.00 36.35 ? 1323 ALA D C 1 ATOM 7655 O O . ALA D 2 36 ? -49.818 137.486 13.300 1.00 33.60 ? 1323 ALA D O 1 ATOM 7656 C CB . ALA D 2 36 ? -48.682 136.447 10.589 1.00 37.22 ? 1323 ALA D CB 1 ATOM 7657 N N . SER D 2 37 ? -48.689 135.606 13.787 1.00 32.95 ? 1324 SER D N 1 ATOM 7658 C CA . SER D 2 37 ? -49.582 135.250 14.886 1.00 51.42 ? 1324 SER D CA 1 ATOM 7659 C C . SER D 2 37 ? -48.858 134.487 15.987 1.00 42.57 ? 1324 SER D C 1 ATOM 7660 O O . SER D 2 37 ? -49.467 133.712 16.722 1.00 50.21 ? 1324 SER D O 1 ATOM 7661 C CB . SER D 2 37 ? -50.754 134.418 14.364 1.00 48.80 ? 1324 SER D CB 1 ATOM 7662 O OG . SER D 2 37 ? -51.697 134.168 15.392 1.00 61.65 ? 1324 SER D OG 1 ATOM 7663 O OXT . SER D 2 37 ? -47.653 134.624 16.172 1.00 47.58 ? 1324 SER D OXT 1 HETATM 7664 C C1 . GOL E 3 . ? -6.654 152.810 -6.394 1.00 23.21 ? 601 GOL A C1 1 HETATM 7665 O O1 . GOL E 3 . ? -5.809 153.052 -7.494 1.00 24.26 ? 601 GOL A O1 1 HETATM 7666 C C2 . GOL E 3 . ? -8.072 152.598 -6.908 1.00 33.52 ? 601 GOL A C2 1 HETATM 7667 O O2 . GOL E 3 . ? -8.045 151.587 -7.890 1.00 32.54 ? 601 GOL A O2 1 HETATM 7668 C C3 . GOL E 3 . ? -8.988 152.190 -5.759 1.00 29.83 ? 601 GOL A C3 1 HETATM 7669 O O3 . GOL E 3 . ? -10.340 152.241 -6.168 1.00 39.15 ? 601 GOL A O3 1 HETATM 7670 C C1 . GOL F 3 . ? 30.306 139.340 8.907 1.00 19.64 ? 602 GOL A C1 1 HETATM 7671 O O1 . GOL F 3 . ? 29.850 138.230 8.161 1.00 24.04 ? 602 GOL A O1 1 HETATM 7672 C C2 . GOL F 3 . ? 31.829 139.307 9.000 1.00 25.92 ? 602 GOL A C2 1 HETATM 7673 O O2 . GOL F 3 . ? 32.343 138.429 8.026 1.00 28.05 ? 602 GOL A O2 1 HETATM 7674 C C3 . GOL F 3 . ? 32.463 140.701 8.886 1.00 28.40 ? 602 GOL A C3 1 HETATM 7675 O O3 . GOL F 3 . ? 32.194 141.380 7.665 1.00 29.07 ? 602 GOL A O3 1 HETATM 7676 C C1 . GOL G 3 . ? 30.047 166.311 7.989 1.00 25.38 ? 603 GOL A C1 1 HETATM 7677 O O1 . GOL G 3 . ? 30.966 165.698 8.861 1.00 18.29 ? 603 GOL A O1 1 HETATM 7678 C C2 . GOL G 3 . ? 30.746 166.667 6.690 1.00 33.94 ? 603 GOL A C2 1 HETATM 7679 O O2 . GOL G 3 . ? 31.955 167.339 6.964 1.00 44.26 ? 603 GOL A O2 1 HETATM 7680 C C3 . GOL G 3 . ? 30.988 165.386 5.909 1.00 37.69 ? 603 GOL A C3 1 HETATM 7681 O O3 . GOL G 3 . ? 32.367 165.109 5.884 1.00 39.76 ? 603 GOL A O3 1 HETATM 7682 S S . SO4 H 4 . ? 21.331 155.704 20.520 1.00 20.88 ? 604 SO4 A S 1 HETATM 7683 O O1 . SO4 H 4 . ? 21.713 157.113 20.361 1.00 23.28 ? 604 SO4 A O1 1 HETATM 7684 O O2 . SO4 H 4 . ? 21.092 155.097 19.215 1.00 28.14 ? 604 SO4 A O2 1 HETATM 7685 O O3 . SO4 H 4 . ? 20.154 155.630 21.383 1.00 28.22 ? 604 SO4 A O3 1 HETATM 7686 O O4 . SO4 H 4 . ? 22.423 154.965 21.157 1.00 26.53 ? 604 SO4 A O4 1 HETATM 7687 S S . SO4 I 4 . ? 14.531 165.606 32.505 1.00 30.63 ? 605 SO4 A S 1 HETATM 7688 O O1 . SO4 I 4 . ? 15.624 166.561 32.342 1.00 33.97 ? 605 SO4 A O1 1 HETATM 7689 O O2 . SO4 I 4 . ? 14.148 165.065 31.200 1.00 27.91 ? 605 SO4 A O2 1 HETATM 7690 O O3 . SO4 I 4 . ? 13.392 166.299 33.116 1.00 24.31 ? 605 SO4 A O3 1 HETATM 7691 O O4 . SO4 I 4 . ? 14.962 164.491 33.350 1.00 27.90 ? 605 SO4 A O4 1 HETATM 7692 S S . SO4 J 4 . ? 33.305 163.178 8.561 1.00 22.75 ? 606 SO4 A S 1 HETATM 7693 O O1 . SO4 J 4 . ? 33.885 164.233 7.733 1.00 30.88 ? 606 SO4 A O1 1 HETATM 7694 O O2 . SO4 J 4 . ? 33.525 161.888 7.905 1.00 24.90 ? 606 SO4 A O2 1 HETATM 7695 O O3 . SO4 J 4 . ? 31.875 163.438 8.731 1.00 25.20 ? 606 SO4 A O3 1 HETATM 7696 O O4 . SO4 J 4 . ? 33.971 163.148 9.862 1.00 27.05 ? 606 SO4 A O4 1 HETATM 7697 C C1 . NAG K 5 . ? 9.347 111.096 -22.026 1.00 41.05 ? 601 NAG B C1 1 HETATM 7698 C C2 . NAG K 5 . ? 9.575 110.051 -23.111 1.00 46.18 ? 601 NAG B C2 1 HETATM 7699 C C3 . NAG K 5 . ? 9.559 110.689 -24.496 1.00 52.45 ? 601 NAG B C3 1 HETATM 7700 C C4 . NAG K 5 . ? 8.334 111.579 -24.671 1.00 48.69 ? 601 NAG B C4 1 HETATM 7701 C C5 . NAG K 5 . ? 8.179 112.533 -23.493 1.00 48.90 ? 601 NAG B C5 1 HETATM 7702 C C6 . NAG K 5 . ? 6.913 113.370 -23.631 1.00 43.03 ? 601 NAG B C6 1 HETATM 7703 C C7 . NAG K 5 . ? 10.890 108.118 -22.462 1.00 49.01 ? 601 NAG B C7 1 HETATM 7704 C C8 . NAG K 5 . ? 12.078 107.767 -21.616 1.00 42.36 ? 601 NAG B C8 1 HETATM 7705 N N2 . NAG K 5 . ? 10.839 109.376 -22.892 1.00 49.33 ? 601 NAG B N2 1 HETATM 7706 O O3 . NAG K 5 . ? 9.550 109.662 -25.494 1.00 55.77 ? 601 NAG B O3 1 HETATM 7707 O O4 . NAG K 5 . ? 8.462 112.333 -25.882 1.00 51.96 ? 601 NAG B O4 1 HETATM 7708 O O5 . NAG K 5 . ? 8.124 111.785 -22.280 1.00 39.23 ? 601 NAG B O5 1 HETATM 7709 O O6 . NAG K 5 . ? 5.787 112.505 -23.822 1.00 51.24 ? 601 NAG B O6 1 HETATM 7710 O O7 . NAG K 5 . ? 10.025 107.303 -22.738 1.00 50.96 ? 601 NAG B O7 1 HETATM 7711 C C1 . GOL L 3 . ? 14.851 111.833 -3.876 1.00 22.12 ? 602 GOL B C1 1 HETATM 7712 O O1 . GOL L 3 . ? 15.515 112.803 -3.084 1.00 24.03 ? 602 GOL B O1 1 HETATM 7713 C C2 . GOL L 3 . ? 15.720 110.592 -4.076 1.00 24.11 ? 602 GOL B C2 1 HETATM 7714 O O2 . GOL L 3 . ? 16.813 110.601 -3.186 1.00 27.40 ? 602 GOL B O2 1 HETATM 7715 C C3 . GOL L 3 . ? 14.927 109.282 -3.972 1.00 32.07 ? 602 GOL B C3 1 HETATM 7716 O O3 . GOL L 3 . ? 14.217 109.135 -2.751 1.00 34.09 ? 602 GOL B O3 1 HETATM 7717 O O . HOH M 6 . ? -21.407 182.323 17.148 1.00 32.77 ? 701 HOH A O 1 HETATM 7718 O O . HOH M 6 . ? -19.032 169.877 23.603 1.00 43.81 ? 702 HOH A O 1 HETATM 7719 O O . HOH M 6 . ? 9.843 161.780 -4.309 1.00 29.77 ? 703 HOH A O 1 HETATM 7720 O O . HOH M 6 . ? 8.169 140.062 18.286 1.00 44.96 ? 704 HOH A O 1 HETATM 7721 O O . HOH M 6 . ? -8.911 183.075 3.636 1.00 44.95 ? 705 HOH A O 1 HETATM 7722 O O . HOH M 6 . ? 28.071 134.188 -10.639 1.00 35.21 ? 706 HOH A O 1 HETATM 7723 O O . HOH M 6 . ? 35.466 134.237 2.910 1.00 35.97 ? 707 HOH A O 1 HETATM 7724 O O . HOH M 6 . ? -5.314 151.571 -10.960 1.00 44.58 ? 708 HOH A O 1 HETATM 7725 O O . HOH M 6 . ? -1.955 148.998 -9.167 1.00 34.78 ? 709 HOH A O 1 HETATM 7726 O O . HOH M 6 . ? -8.874 147.780 5.532 1.00 36.51 ? 710 HOH A O 1 HETATM 7727 O O . HOH M 6 . ? 20.086 159.002 20.328 1.00 16.88 ? 711 HOH A O 1 HETATM 7728 O O . HOH M 6 . ? -3.566 182.758 3.698 1.00 37.96 ? 712 HOH A O 1 HETATM 7729 O O . HOH M 6 . ? 3.073 177.073 27.805 1.00 40.97 ? 713 HOH A O 1 HETATM 7730 O O . HOH M 6 . ? 30.481 129.806 5.681 1.00 27.02 ? 714 HOH A O 1 HETATM 7731 O O . HOH M 6 . ? 14.662 177.361 14.426 1.00 50.11 ? 715 HOH A O 1 HETATM 7732 O O . HOH M 6 . ? 31.858 149.415 -1.601 1.00 37.78 ? 716 HOH A O 1 HETATM 7733 O O . HOH M 6 . ? 13.611 138.865 0.551 1.00 22.14 ? 717 HOH A O 1 HETATM 7734 O O . HOH M 6 . ? -22.802 170.294 16.830 1.00 30.08 ? 718 HOH A O 1 HETATM 7735 O O . HOH M 6 . ? -6.868 149.320 4.581 1.00 29.04 ? 719 HOH A O 1 HETATM 7736 O O . HOH M 6 . ? 18.839 172.434 5.438 1.00 31.83 ? 720 HOH A O 1 HETATM 7737 O O . HOH M 6 . ? 1.080 177.931 -13.249 1.00 48.27 ? 721 HOH A O 1 HETATM 7738 O O . HOH M 6 . ? 3.282 168.515 15.946 1.00 35.28 ? 722 HOH A O 1 HETATM 7739 O O . HOH M 6 . ? 6.316 138.641 8.690 1.00 35.98 ? 723 HOH A O 1 HETATM 7740 O O . HOH M 6 . ? 16.386 157.335 15.756 1.00 15.81 ? 724 HOH A O 1 HETATM 7741 O O . HOH M 6 . ? 23.262 164.536 5.104 1.00 29.25 ? 725 HOH A O 1 HETATM 7742 O O . HOH M 6 . ? 18.522 163.283 -1.766 1.00 26.22 ? 726 HOH A O 1 HETATM 7743 O O . HOH M 6 . ? 14.864 167.111 9.033 1.00 15.45 ? 727 HOH A O 1 HETATM 7744 O O . HOH M 6 . ? 14.604 164.079 35.873 1.00 22.01 ? 728 HOH A O 1 HETATM 7745 O O . HOH M 6 . ? -6.260 180.365 15.725 1.00 32.66 ? 729 HOH A O 1 HETATM 7746 O O . HOH M 6 . ? 17.585 167.752 12.196 1.00 21.86 ? 730 HOH A O 1 HETATM 7747 O O . HOH M 6 . ? -4.376 171.482 -12.137 1.00 19.96 ? 731 HOH A O 1 HETATM 7748 O O . HOH M 6 . ? 8.328 139.969 3.420 1.00 23.31 ? 732 HOH A O 1 HETATM 7749 O O . HOH M 6 . ? 14.622 143.600 5.217 1.00 14.39 ? 733 HOH A O 1 HETATM 7750 O O . HOH M 6 . ? 15.576 171.070 27.987 1.00 35.15 ? 734 HOH A O 1 HETATM 7751 O O . HOH M 6 . ? -4.184 152.111 -9.404 1.00 34.83 ? 735 HOH A O 1 HETATM 7752 O O . HOH M 6 . ? -7.649 152.025 -10.421 1.00 31.53 ? 736 HOH A O 1 HETATM 7753 O O . HOH M 6 . ? 16.909 165.285 -2.408 1.00 38.31 ? 737 HOH A O 1 HETATM 7754 O O . HOH M 6 . ? -15.777 176.084 23.142 1.00 46.88 ? 738 HOH A O 1 HETATM 7755 O O . HOH M 6 . ? 28.763 140.811 23.819 1.00 41.13 ? 739 HOH A O 1 HETATM 7756 O O . HOH M 6 . ? -16.656 160.646 16.888 1.00 32.62 ? 740 HOH A O 1 HETATM 7757 O O . HOH M 6 . ? 23.551 127.341 -12.114 1.00 48.28 ? 741 HOH A O 1 HETATM 7758 O O . HOH M 6 . ? -0.690 176.946 29.459 1.00 19.03 ? 742 HOH A O 1 HETATM 7759 O O . HOH M 6 . ? 1.249 175.127 15.393 1.00 19.45 ? 743 HOH A O 1 HETATM 7760 O O . HOH M 6 . ? 9.439 152.783 -19.639 1.00 34.18 ? 744 HOH A O 1 HETATM 7761 O O . HOH M 6 . ? 7.867 162.253 -2.453 1.00 20.91 ? 745 HOH A O 1 HETATM 7762 O O . HOH M 6 . ? 28.528 145.246 -5.375 1.00 27.44 ? 746 HOH A O 1 HETATM 7763 O O . HOH M 6 . ? -6.267 147.636 -4.274 1.00 34.00 ? 747 HOH A O 1 HETATM 7764 O O . HOH M 6 . ? 25.783 134.639 -9.062 1.00 32.43 ? 748 HOH A O 1 HETATM 7765 O O . HOH M 6 . ? 14.140 128.506 20.114 1.00 25.76 ? 749 HOH A O 1 HETATM 7766 O O . HOH M 6 . ? 11.376 160.432 -17.183 1.00 29.02 ? 750 HOH A O 1 HETATM 7767 O O . HOH M 6 . ? 6.819 147.442 9.078 1.00 29.85 ? 751 HOH A O 1 HETATM 7768 O O . HOH M 6 . ? 7.360 161.259 26.441 1.00 20.44 ? 752 HOH A O 1 HETATM 7769 O O . HOH M 6 . ? -4.595 150.874 13.230 1.00 27.83 ? 753 HOH A O 1 HETATM 7770 O O . HOH M 6 . ? 10.547 147.406 -12.239 1.00 29.56 ? 754 HOH A O 1 HETATM 7771 O O . HOH M 6 . ? -14.848 157.332 -3.143 1.00 25.39 ? 755 HOH A O 1 HETATM 7772 O O . HOH M 6 . ? 0.483 181.445 -3.436 1.00 28.52 ? 756 HOH A O 1 HETATM 7773 O O . HOH M 6 . ? 8.833 164.243 -16.086 1.00 37.35 ? 757 HOH A O 1 HETATM 7774 O O . HOH M 6 . ? -20.847 168.337 -5.236 1.00 31.61 ? 758 HOH A O 1 HETATM 7775 O O . HOH M 6 . ? 6.797 163.248 7.954 1.00 24.89 ? 759 HOH A O 1 HETATM 7776 O O . HOH M 6 . ? -23.879 187.504 13.732 1.00 22.10 ? 760 HOH A O 1 HETATM 7777 O O . HOH M 6 . ? 8.087 179.779 -7.163 1.00 32.62 ? 761 HOH A O 1 HETATM 7778 O O . HOH M 6 . ? 31.450 152.147 -0.352 1.00 31.35 ? 762 HOH A O 1 HETATM 7779 O O . HOH M 6 . ? -4.810 181.855 12.798 1.00 31.96 ? 763 HOH A O 1 HETATM 7780 O O . HOH M 6 . ? 31.659 140.075 -7.127 1.00 32.82 ? 764 HOH A O 1 HETATM 7781 O O . HOH M 6 . ? 21.682 128.989 -7.034 1.00 39.50 ? 765 HOH A O 1 HETATM 7782 O O . HOH M 6 . ? 20.369 141.356 26.006 1.00 33.44 ? 766 HOH A O 1 HETATM 7783 O O . HOH M 6 . ? 12.961 154.769 -11.119 1.00 17.20 ? 767 HOH A O 1 HETATM 7784 O O . HOH M 6 . ? 32.489 126.705 1.115 1.00 34.52 ? 768 HOH A O 1 HETATM 7785 O O . HOH M 6 . ? -0.792 164.859 -5.418 1.00 16.84 ? 769 HOH A O 1 HETATM 7786 O O . HOH M 6 . ? -21.175 174.603 14.871 1.00 18.51 ? 770 HOH A O 1 HETATM 7787 O O . HOH M 6 . ? 34.192 134.502 7.067 1.00 33.17 ? 771 HOH A O 1 HETATM 7788 O O . HOH M 6 . ? 16.044 137.529 -14.066 1.00 30.15 ? 772 HOH A O 1 HETATM 7789 O O . HOH M 6 . ? 0.900 163.393 -16.624 1.00 24.77 ? 773 HOH A O 1 HETATM 7790 O O . HOH M 6 . ? 16.196 159.811 -14.469 1.00 41.48 ? 774 HOH A O 1 HETATM 7791 O O . HOH M 6 . ? 7.564 176.680 7.200 1.00 25.33 ? 775 HOH A O 1 HETATM 7792 O O . HOH M 6 . ? 17.361 128.315 13.734 1.00 22.49 ? 776 HOH A O 1 HETATM 7793 O O . HOH M 6 . ? 20.899 165.499 0.758 1.00 25.43 ? 777 HOH A O 1 HETATM 7794 O O . HOH M 6 . ? 11.668 171.942 27.751 1.00 38.34 ? 778 HOH A O 1 HETATM 7795 O O . HOH M 6 . ? -22.995 165.787 -0.059 1.00 32.32 ? 779 HOH A O 1 HETATM 7796 O O . HOH M 6 . ? -5.182 160.328 18.825 1.00 20.78 ? 780 HOH A O 1 HETATM 7797 O O . HOH M 6 . ? 4.801 166.245 -5.898 1.00 15.23 ? 781 HOH A O 1 HETATM 7798 O O . HOH M 6 . ? 12.676 173.149 26.269 1.00 34.23 ? 782 HOH A O 1 HETATM 7799 O O . HOH M 6 . ? 20.166 156.714 0.625 1.00 11.92 ? 783 HOH A O 1 HETATM 7800 O O . HOH M 6 . ? -8.083 174.758 19.518 1.00 28.85 ? 784 HOH A O 1 HETATM 7801 O O . HOH M 6 . ? 3.356 163.061 24.279 1.00 27.57 ? 785 HOH A O 1 HETATM 7802 O O . HOH M 6 . ? -23.278 170.975 -0.465 1.00 27.69 ? 786 HOH A O 1 HETATM 7803 O O . HOH M 6 . ? 3.848 165.187 -19.567 1.00 40.70 ? 787 HOH A O 1 HETATM 7804 O O . HOH M 6 . ? -22.523 168.315 -0.068 1.00 29.33 ? 788 HOH A O 1 HETATM 7805 O O . HOH M 6 . ? 4.258 165.750 -13.533 1.00 21.40 ? 789 HOH A O 1 HETATM 7806 O O . HOH M 6 . ? -18.212 170.625 19.513 1.00 27.96 ? 790 HOH A O 1 HETATM 7807 O O . HOH M 6 . ? 13.197 158.360 2.774 1.00 12.36 ? 791 HOH A O 1 HETATM 7808 O O . HOH M 6 . ? -18.544 158.081 -3.808 1.00 28.57 ? 792 HOH A O 1 HETATM 7809 O O . HOH M 6 . ? 15.568 136.034 23.781 1.00 31.07 ? 793 HOH A O 1 HETATM 7810 O O . HOH M 6 . ? 5.766 144.190 -7.243 1.00 31.52 ? 794 HOH A O 1 HETATM 7811 O O . HOH M 6 . ? 8.623 147.156 0.297 1.00 16.09 ? 795 HOH A O 1 HETATM 7812 O O . HOH M 6 . ? 0.496 180.972 15.177 1.00 34.53 ? 796 HOH A O 1 HETATM 7813 O O . HOH M 6 . ? -11.723 185.986 13.546 1.00 46.43 ? 797 HOH A O 1 HETATM 7814 O O . HOH M 6 . ? 18.804 171.945 14.063 1.00 28.98 ? 798 HOH A O 1 HETATM 7815 O O . HOH M 6 . ? -14.907 173.808 -14.118 1.00 37.62 ? 799 HOH A O 1 HETATM 7816 O O . HOH M 6 . ? 18.211 131.879 6.037 1.00 17.37 ? 800 HOH A O 1 HETATM 7817 O O . HOH M 6 . ? -8.531 172.525 -4.766 1.00 16.78 ? 801 HOH A O 1 HETATM 7818 O O . HOH M 6 . ? 4.898 145.273 2.038 1.00 28.75 ? 802 HOH A O 1 HETATM 7819 O O . HOH M 6 . ? 17.316 148.981 21.530 1.00 36.79 ? 803 HOH A O 1 HETATM 7820 O O . HOH M 6 . ? 17.907 148.784 -10.128 1.00 28.91 ? 804 HOH A O 1 HETATM 7821 O O . HOH M 6 . ? 26.361 167.910 9.435 1.00 14.06 ? 805 HOH A O 1 HETATM 7822 O O . HOH M 6 . ? 1.965 158.591 -14.299 1.00 27.48 ? 806 HOH A O 1 HETATM 7823 O O . HOH M 6 . ? 8.312 178.831 21.582 1.00 33.42 ? 807 HOH A O 1 HETATM 7824 O O . HOH M 6 . ? -13.879 161.800 11.156 1.00 17.23 ? 808 HOH A O 1 HETATM 7825 O O . HOH M 6 . ? 32.703 155.317 7.832 1.00 21.18 ? 809 HOH A O 1 HETATM 7826 O O . HOH M 6 . ? -2.412 147.906 -6.375 1.00 38.15 ? 810 HOH A O 1 HETATM 7827 O O . HOH M 6 . ? -15.963 153.302 8.131 1.00 43.55 ? 811 HOH A O 1 HETATM 7828 O O . HOH M 6 . ? 26.267 152.366 -1.145 1.00 19.29 ? 812 HOH A O 1 HETATM 7829 O O . HOH M 6 . ? 17.832 145.789 22.330 1.00 26.70 ? 813 HOH A O 1 HETATM 7830 O O . HOH M 6 . ? -18.585 156.121 10.392 1.00 27.56 ? 814 HOH A O 1 HETATM 7831 O O . HOH M 6 . ? -3.165 180.488 9.451 1.00 35.53 ? 815 HOH A O 1 HETATM 7832 O O . HOH M 6 . ? -7.854 153.314 14.063 1.00 31.19 ? 816 HOH A O 1 HETATM 7833 O O . HOH M 6 . ? -10.330 170.155 -17.249 1.00 35.83 ? 817 HOH A O 1 HETATM 7834 O O . HOH M 6 . ? -12.061 154.734 -0.779 1.00 26.72 ? 818 HOH A O 1 HETATM 7835 O O . HOH M 6 . ? -18.656 168.419 -14.928 1.00 47.45 ? 819 HOH A O 1 HETATM 7836 O O . HOH M 6 . ? -14.335 158.199 3.257 1.00 18.56 ? 820 HOH A O 1 HETATM 7837 O O . HOH M 6 . ? 8.283 151.404 20.627 1.00 24.55 ? 821 HOH A O 1 HETATM 7838 O O . HOH M 6 . ? -1.680 159.532 20.168 1.00 24.20 ? 822 HOH A O 1 HETATM 7839 O O . HOH M 6 . ? 11.029 143.209 -1.122 1.00 14.72 ? 823 HOH A O 1 HETATM 7840 O O . HOH M 6 . ? -11.522 177.125 20.115 1.00 22.20 ? 824 HOH A O 1 HETATM 7841 O O . HOH M 6 . ? 21.876 144.599 -4.231 1.00 14.61 ? 825 HOH A O 1 HETATM 7842 O O . HOH M 6 . ? 7.728 175.265 -2.713 1.00 21.10 ? 826 HOH A O 1 HETATM 7843 O O . HOH M 6 . ? -7.090 178.164 6.727 1.00 18.86 ? 827 HOH A O 1 HETATM 7844 O O . HOH M 6 . ? 2.223 161.455 -5.315 1.00 16.69 ? 828 HOH A O 1 HETATM 7845 O O . HOH M 6 . ? 18.892 155.044 -9.887 1.00 16.96 ? 829 HOH A O 1 HETATM 7846 O O . HOH M 6 . ? -2.115 177.578 22.154 1.00 21.29 ? 830 HOH A O 1 HETATM 7847 O O . HOH M 6 . ? -30.871 166.489 15.065 1.00 31.00 ? 831 HOH A O 1 HETATM 7848 O O . HOH M 6 . ? 33.810 146.999 17.579 1.00 16.65 ? 832 HOH A O 1 HETATM 7849 O O . HOH M 6 . ? 5.741 141.497 5.990 1.00 23.37 ? 833 HOH A O 1 HETATM 7850 O O . HOH M 6 . ? 19.517 140.436 20.070 1.00 16.85 ? 834 HOH A O 1 HETATM 7851 O O . HOH M 6 . ? -3.444 164.358 0.881 1.00 13.81 ? 835 HOH A O 1 HETATM 7852 O O . HOH M 6 . ? 10.022 156.973 26.292 1.00 25.42 ? 836 HOH A O 1 HETATM 7853 O O . HOH M 6 . ? 14.199 177.945 8.301 1.00 36.42 ? 837 HOH A O 1 HETATM 7854 O O . HOH M 6 . ? 26.051 154.412 0.666 1.00 18.82 ? 838 HOH A O 1 HETATM 7855 O O . HOH M 6 . ? -8.619 145.053 2.478 1.00 38.48 ? 839 HOH A O 1 HETATM 7856 O O . HOH M 6 . ? -16.875 167.651 15.149 1.00 27.01 ? 840 HOH A O 1 HETATM 7857 O O . HOH M 6 . ? 15.851 141.206 -14.388 1.00 43.19 ? 841 HOH A O 1 HETATM 7858 O O . HOH M 6 . ? 23.883 156.365 0.652 1.00 15.40 ? 842 HOH A O 1 HETATM 7859 O O . HOH M 6 . ? 31.190 156.862 5.970 1.00 26.86 ? 843 HOH A O 1 HETATM 7860 O O . HOH M 6 . ? -1.276 152.120 14.284 1.00 33.39 ? 844 HOH A O 1 HETATM 7861 O O . HOH M 6 . ? 4.246 182.821 18.941 1.00 35.79 ? 845 HOH A O 1 HETATM 7862 O O . HOH M 6 . ? -1.221 171.410 -5.673 1.00 16.32 ? 846 HOH A O 1 HETATM 7863 O O . HOH M 6 . ? 11.221 144.551 -11.066 1.00 33.88 ? 847 HOH A O 1 HETATM 7864 O O . HOH M 6 . ? 13.636 128.422 14.859 1.00 29.96 ? 848 HOH A O 1 HETATM 7865 O O . HOH M 6 . ? 27.913 127.177 -5.985 1.00 33.51 ? 849 HOH A O 1 HETATM 7866 O O . HOH M 6 . ? 15.677 163.201 29.702 1.00 25.62 ? 850 HOH A O 1 HETATM 7867 O O . HOH M 6 . ? 21.034 146.578 -8.521 1.00 19.33 ? 851 HOH A O 1 HETATM 7868 O O . HOH M 6 . ? 4.475 172.686 28.429 1.00 20.77 ? 852 HOH A O 1 HETATM 7869 O O . HOH M 6 . ? -18.181 166.996 -7.100 1.00 36.88 ? 853 HOH A O 1 HETATM 7870 O O . HOH M 6 . ? 13.977 141.691 -7.254 1.00 15.99 ? 854 HOH A O 1 HETATM 7871 O O . HOH M 6 . ? -6.257 175.611 -13.138 1.00 31.65 ? 855 HOH A O 1 HETATM 7872 O O . HOH M 6 . ? 2.669 169.946 2.054 1.00 12.86 ? 856 HOH A O 1 HETATM 7873 O O . HOH M 6 . ? -0.235 179.892 -8.308 1.00 34.77 ? 857 HOH A O 1 HETATM 7874 O O . HOH M 6 . ? 16.547 167.035 -4.526 1.00 25.61 ? 858 HOH A O 1 HETATM 7875 O O . HOH M 6 . ? -3.264 180.726 -9.253 1.00 33.81 ? 859 HOH A O 1 HETATM 7876 O O . HOH M 6 . ? 28.419 140.048 6.054 1.00 14.45 ? 860 HOH A O 1 HETATM 7877 O O . HOH M 6 . ? 21.845 142.714 -8.513 1.00 21.38 ? 861 HOH A O 1 HETATM 7878 O O . HOH M 6 . ? 16.920 142.934 23.508 1.00 37.46 ? 862 HOH A O 1 HETATM 7879 O O . HOH M 6 . ? 4.419 173.272 -12.473 1.00 29.20 ? 863 HOH A O 1 HETATM 7880 O O . HOH M 6 . ? 9.513 155.416 22.869 1.00 33.74 ? 864 HOH A O 1 HETATM 7881 O O . HOH M 6 . ? 2.888 169.998 4.972 1.00 13.73 ? 865 HOH A O 1 HETATM 7882 O O . HOH M 6 . ? 7.989 177.854 -1.805 1.00 29.59 ? 866 HOH A O 1 HETATM 7883 O O . HOH M 6 . ? -12.894 174.774 7.381 1.00 35.65 ? 867 HOH A O 1 HETATM 7884 O O . HOH M 6 . ? 18.401 159.459 -10.954 1.00 26.22 ? 868 HOH A O 1 HETATM 7885 O O . HOH M 6 . ? 37.304 136.795 -5.131 1.00 36.30 ? 869 HOH A O 1 HETATM 7886 O O . HOH M 6 . ? 19.334 160.526 15.580 1.00 13.53 ? 870 HOH A O 1 HETATM 7887 O O . HOH M 6 . ? 11.720 173.488 -3.024 1.00 32.81 ? 871 HOH A O 1 HETATM 7888 O O . HOH M 6 . ? -1.735 148.405 15.598 1.00 35.73 ? 872 HOH A O 1 HETATM 7889 O O . HOH M 6 . ? 22.933 134.332 -17.731 1.00 43.51 ? 873 HOH A O 1 HETATM 7890 O O . HOH M 6 . ? -0.862 145.286 -1.548 1.00 33.39 ? 874 HOH A O 1 HETATM 7891 O O . HOH M 6 . ? 3.244 149.892 16.661 1.00 30.71 ? 875 HOH A O 1 HETATM 7892 O O . HOH M 6 . ? -11.294 181.399 3.720 1.00 26.32 ? 876 HOH A O 1 HETATM 7893 O O . HOH M 6 . ? -2.066 165.621 -7.905 1.00 30.65 ? 877 HOH A O 1 HETATM 7894 O O . HOH M 6 . ? 28.148 138.321 24.158 1.00 39.78 ? 878 HOH A O 1 HETATM 7895 O O . HOH M 6 . ? 3.241 177.825 12.413 1.00 39.68 ? 879 HOH A O 1 HETATM 7896 O O . HOH M 6 . ? -7.224 162.808 11.177 1.00 13.69 ? 880 HOH A O 1 HETATM 7897 O O . HOH M 6 . ? 29.745 155.825 2.681 1.00 26.49 ? 881 HOH A O 1 HETATM 7898 O O . HOH M 6 . ? 22.934 156.448 -6.135 1.00 27.09 ? 882 HOH A O 1 HETATM 7899 O O . HOH M 6 . ? 12.428 141.441 19.904 1.00 29.57 ? 883 HOH A O 1 HETATM 7900 O O . HOH M 6 . ? 30.950 167.508 10.922 1.00 14.07 ? 884 HOH A O 1 HETATM 7901 O O . HOH M 6 . ? -0.249 171.114 -15.299 1.00 34.64 ? 885 HOH A O 1 HETATM 7902 O O . HOH M 6 . ? -4.214 175.514 4.180 1.00 23.86 ? 886 HOH A O 1 HETATM 7903 O O . HOH M 6 . ? 1.840 164.224 -5.744 1.00 17.27 ? 887 HOH A O 1 HETATM 7904 O O . HOH M 6 . ? 14.808 159.219 20.144 1.00 18.46 ? 888 HOH A O 1 HETATM 7905 O O . HOH M 6 . ? 23.312 155.912 23.579 1.00 40.53 ? 889 HOH A O 1 HETATM 7906 O O . HOH M 6 . ? 2.060 174.285 -13.848 1.00 32.63 ? 890 HOH A O 1 HETATM 7907 O O . HOH M 6 . ? -3.589 171.251 -1.459 1.00 14.90 ? 891 HOH A O 1 HETATM 7908 O O . HOH M 6 . ? -26.806 163.517 -0.725 1.00 46.02 ? 892 HOH A O 1 HETATM 7909 O O . HOH M 6 . ? -20.366 185.481 6.571 1.00 34.94 ? 893 HOH A O 1 HETATM 7910 O O . HOH M 6 . ? -21.442 180.395 14.568 1.00 23.87 ? 894 HOH A O 1 HETATM 7911 O O . HOH M 6 . ? 6.336 168.091 28.527 1.00 17.52 ? 895 HOH A O 1 HETATM 7912 O O . HOH M 6 . ? -10.633 182.578 16.778 1.00 34.48 ? 896 HOH A O 1 HETATM 7913 O O . HOH M 6 . ? 21.213 165.533 27.332 1.00 43.54 ? 897 HOH A O 1 HETATM 7914 O O . HOH M 6 . ? 16.744 172.721 11.918 1.00 18.33 ? 898 HOH A O 1 HETATM 7915 O O . HOH M 6 . ? 17.686 163.883 -13.089 1.00 33.18 ? 899 HOH A O 1 HETATM 7916 O O . HOH M 6 . ? 34.445 141.463 0.054 1.00 29.95 ? 900 HOH A O 1 HETATM 7917 O O . HOH M 6 . ? 5.596 162.191 0.705 1.00 12.80 ? 901 HOH A O 1 HETATM 7918 O O . HOH M 6 . ? 29.047 133.466 16.122 1.00 30.11 ? 902 HOH A O 1 HETATM 7919 O O . HOH M 6 . ? -15.220 172.743 9.739 1.00 25.54 ? 903 HOH A O 1 HETATM 7920 O O . HOH M 6 . ? 18.088 169.623 -1.958 1.00 31.11 ? 904 HOH A O 1 HETATM 7921 O O . HOH M 6 . ? 14.736 135.210 14.763 1.00 16.94 ? 905 HOH A O 1 HETATM 7922 O O . HOH M 6 . ? 15.266 165.832 -6.639 1.00 19.27 ? 906 HOH A O 1 HETATM 7923 O O . HOH M 6 . ? 17.477 163.350 33.282 1.00 47.11 ? 907 HOH A O 1 HETATM 7924 O O . HOH M 6 . ? 29.187 128.710 3.329 1.00 30.85 ? 908 HOH A O 1 HETATM 7925 O O . HOH M 6 . ? 10.918 148.119 13.569 1.00 13.71 ? 909 HOH A O 1 HETATM 7926 O O . HOH M 6 . ? 34.766 166.344 9.286 1.00 23.83 ? 910 HOH A O 1 HETATM 7927 O O . HOH M 6 . ? 26.125 129.695 2.431 1.00 17.85 ? 911 HOH A O 1 HETATM 7928 O O . HOH M 6 . ? 11.663 167.309 31.209 1.00 19.54 ? 912 HOH A O 1 HETATM 7929 O O . HOH M 6 . ? 24.562 137.026 -9.638 1.00 26.26 ? 913 HOH A O 1 HETATM 7930 O O . HOH M 6 . ? 12.543 134.341 13.211 1.00 20.37 ? 914 HOH A O 1 HETATM 7931 O O . HOH M 6 . ? -5.019 157.659 18.294 1.00 19.13 ? 915 HOH A O 1 HETATM 7932 O O . HOH M 6 . ? -14.637 156.701 16.018 1.00 26.71 ? 916 HOH A O 1 HETATM 7933 O O . HOH M 6 . ? 27.401 162.180 5.314 1.00 20.34 ? 917 HOH A O 1 HETATM 7934 O O . HOH M 6 . ? 7.789 176.430 22.673 1.00 33.86 ? 918 HOH A O 1 HETATM 7935 O O . HOH M 6 . ? 23.901 138.747 -7.726 1.00 24.09 ? 919 HOH A O 1 HETATM 7936 O O . HOH M 6 . ? -12.392 152.653 7.587 1.00 24.79 ? 920 HOH A O 1 HETATM 7937 O O . HOH M 6 . ? 7.560 144.525 -8.790 1.00 26.77 ? 921 HOH A O 1 HETATM 7938 O O . HOH M 6 . ? 32.790 145.335 0.450 1.00 23.91 ? 922 HOH A O 1 HETATM 7939 O O . HOH M 6 . ? -0.578 143.809 5.785 1.00 38.54 ? 923 HOH A O 1 HETATM 7940 O O . HOH M 6 . ? -0.295 176.089 -16.276 1.00 42.63 ? 924 HOH A O 1 HETATM 7941 O O . HOH M 6 . ? -2.144 173.847 24.386 1.00 17.61 ? 925 HOH A O 1 HETATM 7942 O O . HOH M 6 . ? 28.236 158.797 13.248 1.00 15.47 ? 926 HOH A O 1 HETATM 7943 O O . HOH M 6 . ? 7.829 137.079 10.316 1.00 20.07 ? 927 HOH A O 1 HETATM 7944 O O . HOH M 6 . ? -9.577 158.469 11.401 1.00 15.11 ? 928 HOH A O 1 HETATM 7945 O O . HOH M 6 . ? 1.625 176.334 10.302 1.00 25.43 ? 929 HOH A O 1 HETATM 7946 O O . HOH M 6 . ? 23.950 151.765 -5.654 1.00 17.57 ? 930 HOH A O 1 HETATM 7947 O O . HOH M 6 . ? -12.638 151.232 -4.975 1.00 51.21 ? 931 HOH A O 1 HETATM 7948 O O . HOH M 6 . ? -21.280 175.691 23.151 1.00 31.81 ? 932 HOH A O 1 HETATM 7949 O O . HOH M 6 . ? 14.968 136.345 -9.566 1.00 20.48 ? 933 HOH A O 1 HETATM 7950 O O . HOH M 6 . ? 36.976 145.868 6.531 1.00 24.99 ? 934 HOH A O 1 HETATM 7951 O O . HOH M 6 . ? 4.963 159.757 17.757 1.00 11.51 ? 935 HOH A O 1 HETATM 7952 O O . HOH M 6 . ? 11.159 133.526 3.468 1.00 24.53 ? 936 HOH A O 1 HETATM 7953 O O . HOH M 6 . ? 0.413 166.357 25.603 1.00 21.77 ? 937 HOH A O 1 HETATM 7954 O O . HOH M 6 . ? 8.837 147.103 -14.249 1.00 31.89 ? 938 HOH A O 1 HETATM 7955 O O . HOH M 6 . ? 16.183 173.483 -2.544 1.00 22.18 ? 939 HOH A O 1 HETATM 7956 O O . HOH M 6 . ? 13.466 135.889 19.473 1.00 29.08 ? 940 HOH A O 1 HETATM 7957 O O . HOH M 6 . ? 22.117 138.063 26.191 1.00 39.63 ? 941 HOH A O 1 HETATM 7958 O O . HOH M 6 . ? -21.926 173.737 6.447 1.00 17.93 ? 942 HOH A O 1 HETATM 7959 O O . HOH M 6 . ? 31.141 148.034 2.761 1.00 15.73 ? 943 HOH A O 1 HETATM 7960 O O . HOH M 6 . ? 7.641 180.779 17.943 1.00 34.23 ? 944 HOH A O 1 HETATM 7961 O O . HOH M 6 . ? 28.192 130.334 13.397 1.00 34.41 ? 945 HOH A O 1 HETATM 7962 O O . HOH M 6 . ? 15.639 169.809 10.811 1.00 27.30 ? 946 HOH A O 1 HETATM 7963 O O . HOH M 6 . ? -5.990 165.738 -5.634 1.00 21.50 ? 947 HOH A O 1 HETATM 7964 O O . HOH M 6 . ? 10.075 158.991 -4.287 1.00 22.76 ? 948 HOH A O 1 HETATM 7965 O O . HOH M 6 . ? -12.405 157.566 -12.876 1.00 28.08 ? 949 HOH A O 1 HETATM 7966 O O . HOH M 6 . ? 7.793 155.284 0.487 1.00 13.07 ? 950 HOH A O 1 HETATM 7967 O O . HOH M 6 . ? -6.409 169.377 14.591 1.00 13.54 ? 951 HOH A O 1 HETATM 7968 O O . HOH M 6 . ? -1.129 164.588 -0.794 1.00 13.30 ? 952 HOH A O 1 HETATM 7969 O O . HOH M 6 . ? -1.086 155.346 -14.690 1.00 27.43 ? 953 HOH A O 1 HETATM 7970 O O . HOH M 6 . ? -21.479 153.467 8.304 1.00 46.93 ? 954 HOH A O 1 HETATM 7971 O O . HOH M 6 . ? 15.157 132.126 24.929 1.00 47.18 ? 955 HOH A O 1 HETATM 7972 O O . HOH M 6 . ? 10.942 148.724 1.119 1.00 16.48 ? 956 HOH A O 1 HETATM 7973 O O . HOH M 6 . ? -24.680 180.197 12.155 1.00 28.19 ? 957 HOH A O 1 HETATM 7974 O O . HOH M 6 . ? 15.200 143.382 -10.255 1.00 25.41 ? 958 HOH A O 1 HETATM 7975 O O . HOH M 6 . ? 10.487 134.130 16.433 1.00 35.30 ? 959 HOH A O 1 HETATM 7976 O O . HOH M 6 . ? -7.977 160.384 10.140 1.00 14.62 ? 960 HOH A O 1 HETATM 7977 O O . HOH M 6 . ? 13.297 159.128 -15.261 1.00 23.60 ? 961 HOH A O 1 HETATM 7978 O O . HOH M 6 . ? 3.936 144.630 -9.186 1.00 29.84 ? 962 HOH A O 1 HETATM 7979 O O . HOH M 6 . ? 7.435 138.260 17.267 1.00 35.85 ? 963 HOH A O 1 HETATM 7980 O O . HOH M 6 . ? 0.288 161.157 -13.680 1.00 24.50 ? 964 HOH A O 1 HETATM 7981 O O . HOH M 6 . ? 5.632 142.689 13.493 1.00 30.04 ? 965 HOH A O 1 HETATM 7982 O O . HOH M 6 . ? 35.648 138.829 2.148 1.00 30.66 ? 966 HOH A O 1 HETATM 7983 O O . HOH M 6 . ? 9.177 168.470 28.132 1.00 19.13 ? 967 HOH A O 1 HETATM 7984 O O . HOH M 6 . ? 18.367 171.554 8.191 1.00 27.55 ? 968 HOH A O 1 HETATM 7985 O O . HOH M 6 . ? -6.637 173.842 -15.380 1.00 27.39 ? 969 HOH A O 1 HETATM 7986 O O . HOH M 6 . ? 9.389 173.969 -4.780 1.00 21.58 ? 970 HOH A O 1 HETATM 7987 O O . HOH M 6 . ? 8.562 141.793 19.606 1.00 35.13 ? 971 HOH A O 1 HETATM 7988 O O . HOH M 6 . ? -27.505 175.925 16.273 1.00 21.63 ? 972 HOH A O 1 HETATM 7989 O O . HOH M 6 . ? 16.811 134.798 -14.911 1.00 33.07 ? 973 HOH A O 1 HETATM 7990 O O . HOH M 6 . ? -8.695 159.200 20.894 1.00 38.05 ? 974 HOH A O 1 HETATM 7991 O O . HOH M 6 . ? 7.108 142.854 15.833 1.00 24.30 ? 975 HOH A O 1 HETATM 7992 O O . HOH M 6 . ? 8.581 166.746 21.279 1.00 12.19 ? 976 HOH A O 1 HETATM 7993 O O . HOH M 6 . ? -8.569 180.918 6.242 1.00 35.90 ? 977 HOH A O 1 HETATM 7994 O O . HOH M 6 . ? -14.397 157.301 -10.793 1.00 28.16 ? 978 HOH A O 1 HETATM 7995 O O . HOH M 6 . ? -3.949 164.763 -6.840 1.00 28.36 ? 979 HOH A O 1 HETATM 7996 O O . HOH M 6 . ? -18.707 181.816 18.863 1.00 38.05 ? 980 HOH A O 1 HETATM 7997 O O . HOH M 6 . ? 19.887 164.038 -10.225 1.00 32.44 ? 981 HOH A O 1 HETATM 7998 O O . HOH M 6 . ? 8.817 159.421 -22.609 1.00 42.60 ? 982 HOH A O 1 HETATM 7999 O O . HOH M 6 . ? 12.880 131.515 13.115 1.00 21.40 ? 983 HOH A O 1 HETATM 8000 O O . HOH M 6 . ? 13.836 158.036 24.024 1.00 24.97 ? 984 HOH A O 1 HETATM 8001 O O . HOH M 6 . ? 6.667 185.542 -1.392 1.00 42.08 ? 985 HOH A O 1 HETATM 8002 O O . HOH M 6 . ? -12.361 168.490 0.011 1.00 16.21 ? 986 HOH A O 1 HETATM 8003 O O . HOH M 6 . ? 4.622 143.505 -13.983 1.00 53.03 ? 987 HOH A O 1 HETATM 8004 O O . HOH M 6 . ? -7.310 178.531 -8.852 1.00 34.61 ? 988 HOH A O 1 HETATM 8005 O O . HOH M 6 . ? 8.214 172.189 -11.458 1.00 31.76 ? 989 HOH A O 1 HETATM 8006 O O . HOH M 6 . ? -11.606 181.080 9.461 1.00 23.66 ? 990 HOH A O 1 HETATM 8007 O O . HOH M 6 . ? 15.665 175.899 13.414 1.00 23.65 ? 991 HOH A O 1 HETATM 8008 O O . HOH M 6 . ? 17.985 177.211 16.392 1.00 24.42 ? 992 HOH A O 1 HETATM 8009 O O . HOH M 6 . ? -3.775 155.075 -15.429 1.00 32.40 ? 993 HOH A O 1 HETATM 8010 O O . HOH M 6 . ? 17.834 127.482 -4.371 1.00 32.08 ? 994 HOH A O 1 HETATM 8011 O O . HOH M 6 . ? 16.550 148.784 -2.570 1.00 18.57 ? 995 HOH A O 1 HETATM 8012 O O . HOH M 6 . ? -21.272 158.275 -4.332 1.00 36.29 ? 996 HOH A O 1 HETATM 8013 O O . HOH M 6 . ? -15.354 168.136 19.379 1.00 35.50 ? 997 HOH A O 1 HETATM 8014 O O . HOH M 6 . ? 20.740 128.201 -2.096 1.00 32.75 ? 998 HOH A O 1 HETATM 8015 O O . HOH M 6 . ? -14.539 183.070 6.626 1.00 25.45 ? 999 HOH A O 1 HETATM 8016 O O . HOH M 6 . ? 11.603 132.033 7.045 1.00 23.68 ? 1000 HOH A O 1 HETATM 8017 O O . HOH M 6 . ? -20.080 171.277 -8.767 1.00 24.55 ? 1001 HOH A O 1 HETATM 8018 O O . HOH M 6 . ? 9.901 138.698 -6.173 1.00 33.27 ? 1002 HOH A O 1 HETATM 8019 O O . HOH M 6 . ? -3.178 160.146 21.890 1.00 49.70 ? 1003 HOH A O 1 HETATM 8020 O O . HOH M 6 . ? 10.009 175.933 16.799 1.00 16.38 ? 1004 HOH A O 1 HETATM 8021 O O . HOH M 6 . ? 11.693 168.953 -10.922 1.00 28.57 ? 1005 HOH A O 1 HETATM 8022 O O . HOH M 6 . ? -15.889 175.674 8.781 1.00 22.11 ? 1006 HOH A O 1 HETATM 8023 O O . HOH M 6 . ? 3.168 182.899 5.294 1.00 48.14 ? 1007 HOH A O 1 HETATM 8024 O O . HOH M 6 . ? 16.177 130.437 1.846 1.00 21.44 ? 1008 HOH A O 1 HETATM 8025 O O . HOH M 6 . ? -21.198 163.817 0.734 1.00 23.41 ? 1009 HOH A O 1 HETATM 8026 O O . HOH M 6 . ? -25.911 171.671 18.813 1.00 29.04 ? 1010 HOH A O 1 HETATM 8027 O O . HOH M 6 . ? 35.015 138.725 7.058 1.00 37.61 ? 1011 HOH A O 1 HETATM 8028 O O . HOH M 6 . ? 30.256 138.071 17.441 1.00 20.85 ? 1012 HOH A O 1 HETATM 8029 O O . HOH M 6 . ? -1.981 171.802 -16.800 1.00 48.43 ? 1013 HOH A O 1 HETATM 8030 O O . HOH M 6 . ? 20.091 135.364 24.740 1.00 35.08 ? 1014 HOH A O 1 HETATM 8031 O O . HOH M 6 . ? 20.691 161.378 0.745 1.00 26.53 ? 1015 HOH A O 1 HETATM 8032 O O . HOH M 6 . ? 12.525 132.241 1.145 1.00 26.31 ? 1016 HOH A O 1 HETATM 8033 O O . HOH M 6 . ? 14.402 158.514 27.800 1.00 25.32 ? 1017 HOH A O 1 HETATM 8034 O O . HOH M 6 . ? 18.442 159.777 18.301 1.00 14.29 ? 1018 HOH A O 1 HETATM 8035 O O . HOH M 6 . ? -18.251 151.750 5.893 1.00 40.42 ? 1019 HOH A O 1 HETATM 8036 O O . HOH M 6 . ? 34.911 153.370 7.248 1.00 23.31 ? 1020 HOH A O 1 HETATM 8037 O O . HOH M 6 . ? -7.520 169.555 22.167 1.00 19.49 ? 1021 HOH A O 1 HETATM 8038 O O . HOH M 6 . ? 1.295 156.872 -5.089 1.00 15.52 ? 1022 HOH A O 1 HETATM 8039 O O . HOH M 6 . ? 21.328 165.661 7.094 1.00 21.78 ? 1023 HOH A O 1 HETATM 8040 O O . HOH M 6 . ? -6.161 150.323 -14.783 1.00 42.03 ? 1024 HOH A O 1 HETATM 8041 O O . HOH M 6 . ? 18.922 168.121 1.481 1.00 23.22 ? 1025 HOH A O 1 HETATM 8042 O O . HOH M 6 . ? -4.475 178.582 16.855 1.00 32.41 ? 1026 HOH A O 1 HETATM 8043 O O . HOH M 6 . ? 17.044 167.772 25.836 1.00 20.35 ? 1027 HOH A O 1 HETATM 8044 O O . HOH M 6 . ? -12.502 152.973 14.800 1.00 41.97 ? 1028 HOH A O 1 HETATM 8045 O O . HOH M 6 . ? 2.710 174.228 11.800 1.00 21.15 ? 1029 HOH A O 1 HETATM 8046 O O . HOH M 6 . ? 3.148 154.066 16.308 1.00 22.83 ? 1030 HOH A O 1 HETATM 8047 O O . HOH M 6 . ? 10.467 170.738 -7.659 1.00 17.65 ? 1031 HOH A O 1 HETATM 8048 O O . HOH M 6 . ? 28.907 131.253 7.500 1.00 24.47 ? 1032 HOH A O 1 HETATM 8049 O O . HOH M 6 . ? 19.718 166.579 8.223 1.00 23.97 ? 1033 HOH A O 1 HETATM 8050 O O . HOH M 6 . ? -3.340 172.914 0.719 1.00 14.61 ? 1034 HOH A O 1 HETATM 8051 O O . HOH M 6 . ? 10.339 173.251 24.862 1.00 21.18 ? 1035 HOH A O 1 HETATM 8052 O O . HOH M 6 . ? 12.489 146.034 22.304 1.00 47.88 ? 1036 HOH A O 1 HETATM 8053 O O . HOH M 6 . ? -16.015 155.000 11.151 1.00 27.30 ? 1037 HOH A O 1 HETATM 8054 O O . HOH M 6 . ? 0.294 144.737 3.421 1.00 31.71 ? 1038 HOH A O 1 HETATM 8055 O O . HOH M 6 . ? 6.387 155.559 23.059 1.00 23.43 ? 1039 HOH A O 1 HETATM 8056 O O . HOH M 6 . ? 0.842 156.007 -7.666 1.00 17.68 ? 1040 HOH A O 1 HETATM 8057 O O . HOH M 6 . ? 16.382 177.191 0.679 1.00 38.19 ? 1041 HOH A O 1 HETATM 8058 O O . HOH M 6 . ? -12.907 169.435 -2.534 1.00 16.35 ? 1042 HOH A O 1 HETATM 8059 O O . HOH M 6 . ? 9.776 155.761 3.001 1.00 12.81 ? 1043 HOH A O 1 HETATM 8060 O O . HOH M 6 . ? -11.255 147.889 9.001 1.00 44.13 ? 1044 HOH A O 1 HETATM 8061 O O . HOH M 6 . ? 25.079 130.785 -10.089 1.00 37.72 ? 1045 HOH A O 1 HETATM 8062 O O . HOH M 6 . ? 18.657 153.133 -12.094 1.00 29.44 ? 1046 HOH A O 1 HETATM 8063 O O . HOH M 6 . ? 24.894 135.669 21.530 1.00 24.81 ? 1047 HOH A O 1 HETATM 8064 O O . HOH M 6 . ? 4.924 158.430 12.436 1.00 12.97 ? 1048 HOH A O 1 HETATM 8065 O O . HOH M 6 . ? -11.065 165.573 12.936 1.00 17.05 ? 1049 HOH A O 1 HETATM 8066 O O . HOH M 6 . ? 2.103 147.659 -1.354 1.00 20.70 ? 1050 HOH A O 1 HETATM 8067 O O . HOH M 6 . ? 11.601 140.478 -0.450 1.00 15.00 ? 1051 HOH A O 1 HETATM 8068 O O . HOH M 6 . ? 6.735 174.951 9.713 1.00 27.66 ? 1052 HOH A O 1 HETATM 8069 O O . HOH M 6 . ? 17.518 142.475 19.873 1.00 16.41 ? 1053 HOH A O 1 HETATM 8070 O O . HOH M 6 . ? -13.213 149.611 4.735 1.00 34.04 ? 1054 HOH A O 1 HETATM 8071 O O . HOH M 6 . ? -7.209 153.377 6.384 1.00 23.08 ? 1055 HOH A O 1 HETATM 8072 O O . HOH M 6 . ? -2.844 164.773 -16.035 1.00 34.78 ? 1056 HOH A O 1 HETATM 8073 O O . HOH M 6 . ? 16.900 170.225 13.433 1.00 15.18 ? 1057 HOH A O 1 HETATM 8074 O O . HOH M 6 . ? 30.846 141.902 20.679 1.00 21.28 ? 1058 HOH A O 1 HETATM 8075 O O . HOH M 6 . ? -11.720 146.776 -2.661 1.00 38.47 ? 1059 HOH A O 1 HETATM 8076 O O . HOH M 6 . ? 36.276 151.278 5.065 1.00 24.18 ? 1060 HOH A O 1 HETATM 8077 O O . HOH M 6 . ? 11.707 156.970 4.589 1.00 11.87 ? 1061 HOH A O 1 HETATM 8078 O O . HOH M 6 . ? -23.789 178.736 14.359 1.00 28.10 ? 1062 HOH A O 1 HETATM 8079 O O . HOH M 6 . ? 5.881 146.121 -15.887 1.00 28.31 ? 1063 HOH A O 1 HETATM 8080 O O . HOH M 6 . ? 21.143 158.508 -10.281 1.00 46.82 ? 1064 HOH A O 1 HETATM 8081 O O . HOH M 6 . ? 1.179 149.179 -20.788 1.00 50.31 ? 1065 HOH A O 1 HETATM 8082 O O . HOH M 6 . ? 24.388 172.540 3.472 1.00 19.74 ? 1066 HOH A O 1 HETATM 8083 O O . HOH M 6 . ? 22.008 166.247 3.526 1.00 24.25 ? 1067 HOH A O 1 HETATM 8084 O O . HOH M 6 . ? 12.681 137.662 2.859 1.00 22.84 ? 1068 HOH A O 1 HETATM 8085 O O . HOH M 6 . ? -5.452 163.628 -15.192 1.00 29.54 ? 1069 HOH A O 1 HETATM 8086 O O . HOH M 6 . ? 4.966 170.729 15.318 1.00 16.01 ? 1070 HOH A O 1 HETATM 8087 O O . HOH M 6 . ? -16.331 157.734 0.156 1.00 25.79 ? 1071 HOH A O 1 HETATM 8088 O O . HOH M 6 . ? 24.850 159.039 3.922 1.00 20.00 ? 1072 HOH A O 1 HETATM 8089 O O . HOH M 6 . ? 7.915 174.202 25.197 1.00 42.65 ? 1073 HOH A O 1 HETATM 8090 O O . HOH M 6 . ? 24.482 150.229 -8.020 1.00 29.50 ? 1074 HOH A O 1 HETATM 8091 O O . HOH M 6 . ? 4.470 175.485 13.553 1.00 28.70 ? 1075 HOH A O 1 HETATM 8092 O O . HOH M 6 . ? -27.529 171.108 9.857 1.00 38.27 ? 1076 HOH A O 1 HETATM 8093 O O . HOH M 6 . ? 10.738 139.344 21.077 1.00 35.26 ? 1077 HOH A O 1 HETATM 8094 O O . HOH M 6 . ? -20.915 161.808 13.636 1.00 42.57 ? 1078 HOH A O 1 HETATM 8095 O O . HOH M 6 . ? 17.697 155.751 19.802 1.00 24.00 ? 1079 HOH A O 1 HETATM 8096 O O . HOH M 6 . ? 33.330 157.427 9.748 1.00 19.30 ? 1080 HOH A O 1 HETATM 8097 O O . HOH M 6 . ? 14.610 161.186 35.434 1.00 26.72 ? 1081 HOH A O 1 HETATM 8098 O O . HOH M 6 . ? 2.807 172.625 4.780 1.00 22.94 ? 1082 HOH A O 1 HETATM 8099 O O . HOH M 6 . ? -14.152 178.121 19.835 1.00 22.92 ? 1083 HOH A O 1 HETATM 8100 O O . HOH M 6 . ? -16.512 165.703 19.539 1.00 36.24 ? 1084 HOH A O 1 HETATM 8101 O O . HOH M 6 . ? 15.751 153.136 -9.643 1.00 19.41 ? 1085 HOH A O 1 HETATM 8102 O O . HOH M 6 . ? 16.140 129.185 11.536 1.00 28.96 ? 1086 HOH A O 1 HETATM 8103 O O . HOH M 6 . ? 21.152 128.898 20.022 1.00 28.50 ? 1087 HOH A O 1 HETATM 8104 O O . HOH M 6 . ? -3.709 175.555 21.078 1.00 19.55 ? 1088 HOH A O 1 HETATM 8105 O O . HOH M 6 . ? 4.123 177.751 25.465 1.00 26.31 ? 1089 HOH A O 1 HETATM 8106 O O . HOH M 6 . ? -21.969 164.326 -4.401 1.00 43.86 ? 1090 HOH A O 1 HETATM 8107 O O . HOH M 6 . ? 36.326 148.800 4.440 1.00 30.68 ? 1091 HOH A O 1 HETATM 8108 O O . HOH M 6 . ? -3.143 156.576 12.924 1.00 16.32 ? 1092 HOH A O 1 HETATM 8109 O O . HOH M 6 . ? 9.488 176.386 -6.125 1.00 29.82 ? 1093 HOH A O 1 HETATM 8110 O O . HOH M 6 . ? 13.898 133.507 -12.557 1.00 39.84 ? 1094 HOH A O 1 HETATM 8111 O O . HOH M 6 . ? -2.732 151.792 -17.313 1.00 31.28 ? 1095 HOH A O 1 HETATM 8112 O O . HOH M 6 . ? 14.312 165.398 18.078 1.00 14.01 ? 1096 HOH A O 1 HETATM 8113 O O . HOH M 6 . ? -2.981 142.734 2.633 1.00 49.03 ? 1097 HOH A O 1 HETATM 8114 O O . HOH M 6 . ? 36.263 160.802 8.126 1.00 34.79 ? 1098 HOH A O 1 HETATM 8115 O O . HOH M 6 . ? -13.753 156.011 1.570 1.00 20.57 ? 1099 HOH A O 1 HETATM 8116 O O . HOH M 6 . ? 11.326 135.914 -3.616 1.00 36.22 ? 1100 HOH A O 1 HETATM 8117 O O . HOH M 6 . ? -4.435 174.095 -10.841 1.00 20.30 ? 1101 HOH A O 1 HETATM 8118 O O . HOH M 6 . ? 20.199 152.279 19.203 1.00 35.69 ? 1102 HOH A O 1 HETATM 8119 O O . HOH M 6 . ? 30.827 154.667 12.041 1.00 33.42 ? 1103 HOH A O 1 HETATM 8120 O O . HOH M 6 . ? 22.946 126.258 15.838 1.00 32.76 ? 1104 HOH A O 1 HETATM 8121 O O . HOH M 6 . ? 10.439 178.382 20.032 1.00 36.04 ? 1105 HOH A O 1 HETATM 8122 O O . HOH M 6 . ? -1.575 153.903 10.162 1.00 19.03 ? 1106 HOH A O 1 HETATM 8123 O O . HOH M 6 . ? -21.782 159.231 11.876 1.00 29.13 ? 1107 HOH A O 1 HETATM 8124 O O . HOH M 6 . ? 23.276 161.320 3.672 1.00 16.13 ? 1108 HOH A O 1 HETATM 8125 O O . HOH M 6 . ? 11.353 132.602 10.109 1.00 32.31 ? 1109 HOH A O 1 HETATM 8126 O O . HOH M 6 . ? -2.784 163.012 23.528 1.00 33.59 ? 1110 HOH A O 1 HETATM 8127 O O . HOH M 6 . ? 0.305 179.654 -5.116 1.00 29.24 ? 1111 HOH A O 1 HETATM 8128 O O . HOH M 6 . ? 12.198 139.560 4.821 1.00 21.68 ? 1112 HOH A O 1 HETATM 8129 O O . HOH M 6 . ? 11.113 151.481 -16.420 1.00 28.15 ? 1113 HOH A O 1 HETATM 8130 O O . HOH M 6 . ? 36.339 136.400 -8.250 1.00 39.16 ? 1114 HOH A O 1 HETATM 8131 O O . HOH M 6 . ? 2.053 158.779 1.191 1.00 25.26 ? 1115 HOH A O 1 HETATM 8132 O O . HOH M 6 . ? 15.816 154.346 15.672 1.00 20.18 ? 1116 HOH A O 1 HETATM 8133 O O . HOH M 6 . ? -13.540 172.194 7.800 1.00 30.87 ? 1117 HOH A O 1 HETATM 8134 O O . HOH M 6 . ? 13.570 152.334 -12.194 1.00 23.14 ? 1118 HOH A O 1 HETATM 8135 O O . HOH M 6 . ? 16.770 149.791 9.786 1.00 18.15 ? 1119 HOH A O 1 HETATM 8136 O O . HOH M 6 . ? 28.939 148.992 -4.060 1.00 23.23 ? 1120 HOH A O 1 HETATM 8137 O O . HOH M 6 . ? 7.797 142.929 3.079 1.00 22.10 ? 1121 HOH A O 1 HETATM 8138 O O . HOH M 6 . ? 17.612 168.357 9.508 1.00 26.24 ? 1122 HOH A O 1 HETATM 8139 O O . HOH M 6 . ? 28.977 147.634 25.893 1.00 45.77 ? 1123 HOH A O 1 HETATM 8140 O O . HOH M 6 . ? 5.096 139.928 12.313 1.00 31.89 ? 1124 HOH A O 1 HETATM 8141 O O . HOH M 6 . ? 27.069 153.754 16.454 1.00 21.69 ? 1125 HOH A O 1 HETATM 8142 O O . HOH M 6 . ? 24.584 137.113 24.515 1.00 34.98 ? 1126 HOH A O 1 HETATM 8143 O O . HOH M 6 . ? 12.936 177.464 12.780 1.00 36.28 ? 1127 HOH A O 1 HETATM 8144 O O . HOH M 6 . ? 14.429 154.797 -18.450 1.00 39.02 ? 1128 HOH A O 1 HETATM 8145 O O . HOH M 6 . ? -20.069 164.416 14.642 1.00 43.43 ? 1129 HOH A O 1 HETATM 8146 O O . HOH M 6 . ? 13.430 134.401 17.102 1.00 27.37 ? 1130 HOH A O 1 HETATM 8147 O O . HOH M 6 . ? 15.710 150.714 -11.028 1.00 38.08 ? 1131 HOH A O 1 HETATM 8148 O O . HOH M 6 . ? -22.431 180.402 17.633 1.00 36.52 ? 1132 HOH A O 1 HETATM 8149 O O . HOH M 6 . ? -2.055 177.677 7.457 1.00 30.62 ? 1133 HOH A O 1 HETATM 8150 O O . HOH M 6 . ? 10.143 147.485 21.334 1.00 18.98 ? 1134 HOH A O 1 HETATM 8151 O O . HOH M 6 . ? 8.748 172.147 26.753 1.00 33.15 ? 1135 HOH A O 1 HETATM 8152 O O . HOH M 6 . ? 0.880 152.262 15.946 1.00 38.68 ? 1136 HOH A O 1 HETATM 8153 O O . HOH M 6 . ? -12.930 152.138 10.190 1.00 28.40 ? 1137 HOH A O 1 HETATM 8154 O O . HOH M 6 . ? 17.243 129.968 22.004 1.00 29.44 ? 1138 HOH A O 1 HETATM 8155 O O . HOH M 6 . ? 14.914 178.565 22.548 1.00 37.06 ? 1139 HOH A O 1 HETATM 8156 O O . HOH M 6 . ? 19.830 140.140 -13.714 1.00 27.18 ? 1140 HOH A O 1 HETATM 8157 O O . HOH M 6 . ? 0.983 184.460 -4.394 1.00 47.23 ? 1141 HOH A O 1 HETATM 8158 O O . HOH M 6 . ? 8.749 140.057 -3.573 1.00 31.27 ? 1142 HOH A O 1 HETATM 8159 O O . HOH M 6 . ? -3.707 172.235 -4.167 1.00 21.36 ? 1143 HOH A O 1 HETATM 8160 O O . HOH M 6 . ? 0.470 154.317 -18.642 1.00 42.07 ? 1144 HOH A O 1 HETATM 8161 O O . HOH M 6 . ? 20.759 168.139 13.359 1.00 25.52 ? 1145 HOH A O 1 HETATM 8162 O O . HOH M 6 . ? -15.157 165.784 -15.939 1.00 41.76 ? 1146 HOH A O 1 HETATM 8163 O O . HOH M 6 . ? 27.227 128.593 4.381 1.00 42.81 ? 1147 HOH A O 1 HETATM 8164 O O . HOH M 6 . ? 0.557 156.669 -12.806 1.00 21.36 ? 1148 HOH A O 1 HETATM 8165 O O . HOH M 6 . ? 11.847 158.890 34.319 1.00 30.20 ? 1149 HOH A O 1 HETATM 8166 O O . HOH M 6 . ? -26.652 169.906 16.266 1.00 41.86 ? 1150 HOH A O 1 HETATM 8167 O O . HOH M 6 . ? 35.025 140.724 5.562 1.00 42.77 ? 1151 HOH A O 1 HETATM 8168 O O . HOH M 6 . ? 14.962 151.100 21.861 1.00 34.87 ? 1152 HOH A O 1 HETATM 8169 O O . HOH M 6 . ? 4.328 178.672 -8.428 1.00 38.60 ? 1153 HOH A O 1 HETATM 8170 O O . HOH M 6 . ? 14.731 142.678 20.544 1.00 26.80 ? 1154 HOH A O 1 HETATM 8171 O O . HOH M 6 . ? 23.727 127.332 -2.380 1.00 44.58 ? 1155 HOH A O 1 HETATM 8172 O O . HOH M 6 . ? 35.221 142.986 7.188 1.00 28.80 ? 1156 HOH A O 1 HETATM 8173 O O . HOH M 6 . ? 17.162 167.022 34.982 1.00 44.12 ? 1157 HOH A O 1 HETATM 8174 O O . HOH M 6 . ? -23.591 171.246 21.675 1.00 35.68 ? 1158 HOH A O 1 HETATM 8175 O O . HOH M 6 . ? 0.504 180.812 20.368 1.00 26.24 ? 1159 HOH A O 1 HETATM 8176 O O . HOH M 6 . ? 30.784 139.161 19.805 1.00 24.65 ? 1160 HOH A O 1 HETATM 8177 O O . HOH M 6 . ? -12.046 153.407 -12.883 1.00 45.64 ? 1161 HOH A O 1 HETATM 8178 O O . HOH M 6 . ? -5.968 146.185 4.453 1.00 40.10 ? 1162 HOH A O 1 HETATM 8179 O O . HOH M 6 . ? 9.478 159.928 30.370 1.00 30.70 ? 1163 HOH A O 1 HETATM 8180 O O . HOH M 6 . ? -15.473 146.804 -0.576 1.00 49.51 ? 1164 HOH A O 1 HETATM 8181 O O . HOH M 6 . ? -9.090 174.120 -16.744 1.00 39.57 ? 1165 HOH A O 1 HETATM 8182 O O . HOH M 6 . ? -13.486 164.459 12.031 1.00 28.36 ? 1166 HOH A O 1 HETATM 8183 O O . HOH M 6 . ? 20.120 134.590 -18.309 1.00 49.90 ? 1167 HOH A O 1 HETATM 8184 O O . HOH M 6 . ? 16.900 166.473 28.191 1.00 31.82 ? 1168 HOH A O 1 HETATM 8185 O O . HOH M 6 . ? 28.110 144.937 29.179 1.00 48.47 ? 1169 HOH A O 1 HETATM 8186 O O . HOH M 6 . ? -6.639 161.580 -16.018 1.00 34.56 ? 1170 HOH A O 1 HETATM 8187 O O . HOH M 6 . ? 3.939 174.404 9.179 1.00 25.10 ? 1171 HOH A O 1 HETATM 8188 O O . HOH M 6 . ? -18.195 178.196 -11.779 1.00 36.02 ? 1172 HOH A O 1 HETATM 8189 O O . HOH M 6 . ? -4.580 178.223 3.547 1.00 39.56 ? 1173 HOH A O 1 HETATM 8190 O O . HOH M 6 . ? -2.157 181.057 19.359 1.00 45.89 ? 1174 HOH A O 1 HETATM 8191 O O . HOH M 6 . ? 37.066 162.499 9.834 1.00 31.20 ? 1175 HOH A O 1 HETATM 8192 O O . HOH M 6 . ? 32.984 157.283 2.830 1.00 46.25 ? 1176 HOH A O 1 HETATM 8193 O O . HOH M 6 . ? -13.401 152.960 -3.223 1.00 42.96 ? 1177 HOH A O 1 HETATM 8194 O O . HOH M 6 . ? 19.070 171.203 3.165 1.00 38.03 ? 1178 HOH A O 1 HETATM 8195 O O . HOH M 6 . ? 17.422 167.074 -0.686 1.00 33.81 ? 1179 HOH A O 1 HETATM 8196 O O . HOH M 6 . ? 15.213 174.778 25.887 1.00 42.26 ? 1180 HOH A O 1 HETATM 8197 O O . HOH M 6 . ? -15.508 161.721 -12.867 1.00 35.51 ? 1181 HOH A O 1 HETATM 8198 O O . HOH M 6 . ? 6.414 158.550 26.301 1.00 38.39 ? 1182 HOH A O 1 HETATM 8199 O O . HOH M 6 . ? 13.692 169.451 -9.666 1.00 40.30 ? 1183 HOH A O 1 HETATM 8200 O O . HOH M 6 . ? -11.907 175.611 22.341 1.00 38.63 ? 1184 HOH A O 1 HETATM 8201 O O . HOH M 6 . ? 2.353 179.732 -11.141 1.00 43.21 ? 1185 HOH A O 1 HETATM 8202 O O . HOH M 6 . ? -11.462 147.962 4.858 1.00 46.58 ? 1186 HOH A O 1 HETATM 8203 O O . HOH M 6 . ? 30.398 152.073 14.752 1.00 26.84 ? 1187 HOH A O 1 HETATM 8204 O O . HOH M 6 . ? 43.852 133.018 2.857 1.00 45.60 ? 1188 HOH A O 1 HETATM 8205 O O . HOH M 6 . ? 5.084 144.944 15.889 1.00 36.49 ? 1189 HOH A O 1 HETATM 8206 O O . HOH M 6 . ? 7.164 136.380 14.777 1.00 45.68 ? 1190 HOH A O 1 HETATM 8207 O O . HOH M 6 . ? 18.040 173.516 3.434 1.00 40.15 ? 1191 HOH A O 1 HETATM 8208 O O . HOH M 6 . ? 22.674 162.575 -2.221 1.00 41.51 ? 1192 HOH A O 1 HETATM 8209 O O . HOH M 6 . ? 28.349 155.742 15.684 1.00 23.41 ? 1193 HOH A O 1 HETATM 8210 O O . HOH M 6 . ? -2.081 153.859 12.386 1.00 30.68 ? 1194 HOH A O 1 HETATM 8211 O O . HOH M 6 . ? -1.993 154.513 20.303 1.00 43.40 ? 1195 HOH A O 1 HETATM 8212 O O . HOH M 6 . ? 44.772 131.953 1.711 1.00 55.50 ? 1196 HOH A O 1 HETATM 8213 O O . HOH M 6 . ? 29.648 130.763 10.025 1.00 45.21 ? 1197 HOH A O 1 HETATM 8214 O O . HOH M 6 . ? 19.407 159.404 22.296 1.00 42.33 ? 1198 HOH A O 1 HETATM 8215 O O . HOH M 6 . ? 29.622 131.188 17.416 1.00 38.44 ? 1199 HOH A O 1 HETATM 8216 O O . HOH M 6 . ? -13.515 173.616 11.785 1.00 20.84 ? 1200 HOH A O 1 HETATM 8217 O O . HOH M 6 . ? 9.990 171.613 -10.242 1.00 29.73 ? 1201 HOH A O 1 HETATM 8218 O O . HOH M 6 . ? 27.462 159.622 4.454 1.00 24.65 ? 1202 HOH A O 1 HETATM 8219 O O . HOH M 6 . ? 22.569 127.522 -13.926 1.00 36.44 ? 1203 HOH A O 1 HETATM 8220 O O . HOH M 6 . ? 16.051 152.432 -13.252 1.00 47.79 ? 1204 HOH A O 1 HETATM 8221 O O . HOH M 6 . ? 2.807 145.253 -0.301 1.00 36.90 ? 1205 HOH A O 1 HETATM 8222 O O . HOH M 6 . ? 13.501 137.899 -8.063 1.00 22.11 ? 1206 HOH A O 1 HETATM 8223 O O . HOH M 6 . ? -18.528 156.799 -1.472 1.00 43.89 ? 1207 HOH A O 1 HETATM 8224 O O . HOH M 6 . ? 24.681 158.874 1.359 1.00 27.66 ? 1208 HOH A O 1 HETATM 8225 O O . HOH M 6 . ? -13.697 159.945 -13.984 1.00 44.17 ? 1209 HOH A O 1 HETATM 8226 O O . HOH M 6 . ? 6.656 180.555 3.595 1.00 47.07 ? 1210 HOH A O 1 HETATM 8227 O O . HOH M 6 . ? 23.231 154.059 -7.163 1.00 24.66 ? 1211 HOH A O 1 HETATM 8228 O O . HOH M 6 . ? 13.462 152.512 -18.295 1.00 41.81 ? 1212 HOH A O 1 HETATM 8229 O O . HOH M 6 . ? 18.968 127.011 11.809 1.00 38.17 ? 1213 HOH A O 1 HETATM 8230 O O . HOH M 6 . ? 10.873 177.398 14.873 1.00 41.95 ? 1214 HOH A O 1 HETATM 8231 O O . HOH M 6 . ? 19.946 170.150 13.753 1.00 35.29 ? 1215 HOH A O 1 HETATM 8232 O O . HOH M 6 . ? 24.339 146.952 28.235 1.00 47.85 ? 1216 HOH A O 1 HETATM 8233 O O . HOH M 6 . ? 36.479 146.135 17.382 1.00 19.17 ? 1217 HOH A O 1 HETATM 8234 O O . HOH M 6 . ? -16.871 157.867 17.592 1.00 42.92 ? 1218 HOH A O 1 HETATM 8235 O O . HOH M 6 . ? 15.880 160.246 30.313 1.00 41.47 ? 1219 HOH A O 1 HETATM 8236 O O . HOH M 6 . ? 30.872 127.873 7.683 1.00 45.35 ? 1220 HOH A O 1 HETATM 8237 O O . HOH M 6 . ? 21.360 155.573 -10.144 1.00 39.71 ? 1221 HOH A O 1 HETATM 8238 O O . HOH M 6 . ? -0.449 181.038 23.300 1.00 52.18 ? 1222 HOH A O 1 HETATM 8239 O O . HOH M 6 . ? 7.708 143.836 20.000 1.00 38.82 ? 1223 HOH A O 1 HETATM 8240 O O . HOH M 6 . ? 12.217 140.049 -9.170 1.00 32.89 ? 1224 HOH A O 1 HETATM 8241 O O . HOH M 6 . ? -4.748 180.638 4.516 1.00 40.41 ? 1225 HOH A O 1 HETATM 8242 O O . HOH M 6 . ? 33.274 142.197 21.488 1.00 37.72 ? 1226 HOH A O 1 HETATM 8243 O O . HOH M 6 . ? 16.897 154.026 18.269 1.00 35.22 ? 1227 HOH A O 1 HETATM 8244 O O . HOH M 6 . ? 19.624 142.571 -12.383 1.00 34.78 ? 1228 HOH A O 1 HETATM 8245 O O . HOH M 6 . ? 22.684 134.599 24.096 1.00 50.86 ? 1229 HOH A O 1 HETATM 8246 O O . HOH M 6 . ? 1.464 165.340 -18.335 1.00 41.38 ? 1230 HOH A O 1 HETATM 8247 O O . HOH M 6 . ? -15.877 185.164 7.028 1.00 41.85 ? 1231 HOH A O 1 HETATM 8248 O O . HOH M 6 . ? -23.096 184.783 4.009 1.00 46.56 ? 1232 HOH A O 1 HETATM 8249 O O . HOH M 6 . ? 8.902 145.070 21.831 1.00 33.53 ? 1233 HOH A O 1 HETATM 8250 O O . HOH M 6 . ? 30.750 159.434 5.166 1.00 51.69 ? 1234 HOH A O 1 HETATM 8251 O O . HOH M 6 . ? -18.833 168.075 20.234 1.00 43.25 ? 1235 HOH A O 1 HETATM 8252 O O . HOH M 6 . ? 17.681 158.146 23.846 1.00 44.67 ? 1236 HOH A O 1 HETATM 8253 O O . HOH M 6 . ? 37.859 144.447 18.949 1.00 31.04 ? 1237 HOH A O 1 HETATM 8254 O O . HOH M 6 . ? 6.484 176.038 12.319 1.00 37.18 ? 1238 HOH A O 1 HETATM 8255 O O . HOH M 6 . ? 31.328 136.205 10.975 1.00 30.28 ? 1239 HOH A O 1 HETATM 8256 O O . HOH M 6 . ? 8.760 144.256 0.148 1.00 21.63 ? 1240 HOH A O 1 HETATM 8257 O O . HOH M 6 . ? 35.732 167.488 6.960 1.00 43.91 ? 1241 HOH A O 1 HETATM 8258 O O . HOH M 6 . ? -8.281 181.576 17.333 1.00 47.19 ? 1242 HOH A O 1 HETATM 8259 O O . HOH M 6 . ? 17.384 173.093 27.575 1.00 43.68 ? 1243 HOH A O 1 HETATM 8260 O O . HOH M 6 . ? 2.495 153.224 -20.825 1.00 44.87 ? 1244 HOH A O 1 HETATM 8261 O O . HOH M 6 . ? 5.501 175.212 27.631 1.00 36.91 ? 1245 HOH A O 1 HETATM 8262 O O . HOH M 6 . ? -8.377 158.217 24.428 1.00 47.87 ? 1246 HOH A O 1 HETATM 8263 O O . HOH M 6 . ? -7.477 179.700 -11.229 1.00 44.97 ? 1247 HOH A O 1 HETATM 8264 O O . HOH M 6 . ? 11.841 136.307 -6.752 1.00 41.50 ? 1248 HOH A O 1 HETATM 8265 O O . HOH M 6 . ? -23.359 165.748 -2.952 1.00 46.35 ? 1249 HOH A O 1 HETATM 8266 O O . HOH M 6 . ? -19.418 166.320 15.745 1.00 44.48 ? 1250 HOH A O 1 HETATM 8267 O O . HOH M 6 . ? 21.768 143.590 -11.162 1.00 28.82 ? 1251 HOH A O 1 HETATM 8268 O O . HOH M 6 . ? -20.578 168.851 -7.928 1.00 44.81 ? 1252 HOH A O 1 HETATM 8269 O O . HOH M 6 . ? -6.114 176.427 19.922 1.00 30.55 ? 1253 HOH A O 1 HETATM 8270 O O . HOH M 6 . ? -13.676 155.198 17.819 1.00 35.49 ? 1254 HOH A O 1 HETATM 8271 O O . HOH M 6 . ? 22.990 161.545 1.080 1.00 40.54 ? 1255 HOH A O 1 HETATM 8272 O O . HOH M 6 . ? 16.942 143.602 -12.639 1.00 39.09 ? 1256 HOH A O 1 HETATM 8273 O O . HOH M 6 . ? -16.462 181.753 18.717 1.00 36.03 ? 1257 HOH A O 1 HETATM 8274 O O . HOH M 6 . ? 22.312 144.757 -7.039 1.00 18.54 ? 1258 HOH A O 1 HETATM 8275 O O . HOH M 6 . ? 18.234 140.193 -16.388 1.00 44.11 ? 1259 HOH A O 1 HETATM 8276 O O . HOH M 6 . ? 6.970 143.235 -14.021 1.00 49.75 ? 1260 HOH A O 1 HETATM 8277 O O . HOH M 6 . ? -15.300 145.723 2.118 1.00 45.46 ? 1261 HOH A O 1 HETATM 8278 O O . HOH M 6 . ? -13.637 143.905 0.849 1.00 36.67 ? 1262 HOH A O 1 HETATM 8279 O O . HOH M 6 . ? 28.589 159.247 2.389 1.00 46.35 ? 1263 HOH A O 1 HETATM 8280 O O . HOH M 6 . ? 31.282 141.534 23.499 1.00 38.35 ? 1264 HOH A O 1 HETATM 8281 O O . HOH M 6 . ? 11.595 136.482 -1.081 1.00 33.92 ? 1265 HOH A O 1 HETATM 8282 O O . HOH M 6 . ? 14.062 136.336 -12.074 1.00 32.01 ? 1266 HOH A O 1 HETATM 8283 O O . HOH M 6 . ? -3.026 157.372 20.222 1.00 37.32 ? 1267 HOH A O 1 HETATM 8284 O O . HOH M 6 . ? 33.682 143.780 -1.872 1.00 43.46 ? 1268 HOH A O 1 HETATM 8285 O O . HOH M 6 . ? 25.562 156.007 -3.512 1.00 42.19 ? 1269 HOH A O 1 HETATM 8286 O O . HOH M 6 . ? 10.401 178.428 -3.363 1.00 41.09 ? 1270 HOH A O 1 HETATM 8287 O O . HOH M 6 . ? 16.166 155.519 22.088 1.00 38.66 ? 1271 HOH A O 1 HETATM 8288 O O . HOH M 6 . ? -0.488 164.005 24.365 1.00 33.51 ? 1272 HOH A O 1 HETATM 8289 O O . HOH M 6 . ? 33.509 168.309 10.679 1.00 14.75 ? 1273 HOH A O 1 HETATM 8290 O O . HOH M 6 . ? 10.403 153.403 22.791 1.00 49.69 ? 1274 HOH A O 1 HETATM 8291 O O . HOH M 6 . ? -20.590 156.795 12.460 1.00 42.89 ? 1275 HOH A O 1 HETATM 8292 O O . HOH M 6 . ? 3.211 177.174 -13.825 1.00 46.21 ? 1276 HOH A O 1 HETATM 8293 O O . HOH M 6 . ? 25.111 163.123 4.199 1.00 26.53 ? 1277 HOH A O 1 HETATM 8294 O O . HOH M 6 . ? 9.846 179.234 17.807 1.00 41.46 ? 1278 HOH A O 1 HETATM 8295 O O . HOH M 6 . ? -4.589 177.786 5.656 1.00 34.47 ? 1279 HOH A O 1 HETATM 8296 O O . HOH M 6 . ? 18.566 130.736 3.633 1.00 33.71 ? 1280 HOH A O 1 HETATM 8297 O O . HOH M 6 . ? -9.628 157.791 22.684 1.00 48.52 ? 1281 HOH A O 1 HETATM 8298 O O . HOH M 6 . ? 14.541 178.212 -0.284 1.00 40.77 ? 1282 HOH A O 1 HETATM 8299 O O . HOH M 6 . ? 38.724 142.901 17.027 1.00 45.03 ? 1283 HOH A O 1 HETATM 8300 O O . HOH M 6 . ? -14.787 178.808 22.266 1.00 37.51 ? 1284 HOH A O 1 HETATM 8301 O O . HOH M 6 . ? -4.732 173.869 -17.495 1.00 45.87 ? 1285 HOH A O 1 HETATM 8302 O O . HOH M 6 . ? 4.977 152.117 16.952 1.00 27.10 ? 1286 HOH A O 1 HETATM 8303 O O . HOH M 6 . ? -1.333 160.419 22.974 1.00 47.59 ? 1287 HOH A O 1 HETATM 8304 O O . HOH M 6 . ? 10.425 136.980 1.643 1.00 42.86 ? 1288 HOH A O 1 HETATM 8305 O O . HOH M 6 . ? 35.511 140.182 14.736 1.00 40.38 ? 1289 HOH A O 1 HETATM 8306 O O . HOH M 6 . ? 26.218 148.036 -8.004 1.00 43.31 ? 1290 HOH A O 1 HETATM 8307 O O . HOH M 6 . ? 29.910 132.011 27.882 1.00 47.92 ? 1291 HOH A O 1 HETATM 8308 O O . HOH M 6 . ? 35.779 158.420 8.791 1.00 27.02 ? 1292 HOH A O 1 HETATM 8309 O O . HOH M 6 . ? 7.417 142.432 -10.890 1.00 37.52 ? 1293 HOH A O 1 HETATM 8310 O O . HOH M 6 . ? 41.232 136.400 -5.184 1.00 49.68 ? 1294 HOH A O 1 HETATM 8311 O O . HOH M 6 . ? 38.685 126.218 4.570 1.00 44.49 ? 1295 HOH A O 1 HETATM 8312 O O . HOH M 6 . ? 26.948 146.351 -7.365 1.00 41.64 ? 1296 HOH A O 1 HETATM 8313 O O . HOH M 6 . ? 5.591 177.475 -12.525 1.00 37.95 ? 1297 HOH A O 1 HETATM 8314 O O . HOH M 6 . ? 28.390 155.809 0.435 1.00 37.78 ? 1298 HOH A O 1 HETATM 8315 O O . HOH M 6 . ? -2.958 145.329 -7.043 1.00 52.86 ? 1299 HOH A O 1 HETATM 8316 O O . HOH M 6 . ? -15.386 152.703 10.157 1.00 45.59 ? 1300 HOH A O 1 HETATM 8317 O O . HOH M 6 . ? -4.883 152.772 -16.046 1.00 34.84 ? 1301 HOH A O 1 HETATM 8318 O O . HOH M 6 . ? 0.117 157.844 -16.565 1.00 41.10 ? 1302 HOH A O 1 HETATM 8319 O O . HOH M 6 . ? 29.773 129.195 11.274 1.00 53.31 ? 1303 HOH A O 1 HETATM 8320 O O . HOH M 6 . ? 8.914 149.292 22.755 1.00 40.87 ? 1304 HOH A O 1 HETATM 8321 O O . HOH M 6 . ? 5.596 140.260 16.352 1.00 40.75 ? 1305 HOH A O 1 HETATM 8322 O O . HOH M 6 . ? 11.582 143.551 22.366 1.00 45.49 ? 1306 HOH A O 1 HETATM 8323 O O . HOH M 6 . ? 21.816 146.780 -11.118 1.00 33.82 ? 1307 HOH A O 1 HETATM 8324 O O . HOH M 6 . ? 4.362 171.255 -14.454 1.00 40.98 ? 1308 HOH A O 1 HETATM 8325 O O . HOH M 6 . ? 10.053 157.339 33.631 1.00 37.48 ? 1309 HOH A O 1 HETATM 8326 O O . HOH M 6 . ? 5.883 138.704 2.982 1.00 49.60 ? 1310 HOH A O 1 HETATM 8327 O O . HOH M 6 . ? -19.056 158.246 -15.659 1.00 45.21 ? 1311 HOH A O 1 HETATM 8328 O O . HOH M 6 . ? 10.203 157.986 29.012 1.00 38.70 ? 1312 HOH A O 1 HETATM 8329 O O . HOH M 6 . ? 24.802 127.469 1.792 1.00 31.56 ? 1313 HOH A O 1 HETATM 8330 O O . HOH M 6 . ? 14.532 133.774 -8.374 1.00 32.54 ? 1314 HOH A O 1 HETATM 8331 O O . HOH M 6 . ? 36.235 136.359 6.230 1.00 40.98 ? 1315 HOH A O 1 HETATM 8332 O O . HOH M 6 . ? 6.212 143.465 -0.177 1.00 44.11 ? 1316 HOH A O 1 HETATM 8333 O O . HOH M 6 . ? 22.364 139.972 -14.474 1.00 33.48 ? 1317 HOH A O 1 HETATM 8334 O O . HOH M 6 . ? 19.171 126.833 4.204 1.00 37.04 ? 1318 HOH A O 1 HETATM 8335 O O . HOH M 6 . ? -23.361 168.405 -3.460 1.00 42.64 ? 1319 HOH A O 1 HETATM 8336 O O . HOH M 6 . ? 3.238 178.543 30.263 1.00 41.68 ? 1320 HOH A O 1 HETATM 8337 O O . HOH M 6 . ? -25.029 179.753 16.332 1.00 23.39 ? 1321 HOH A O 1 HETATM 8338 O O . HOH M 6 . ? 13.181 137.054 24.874 1.00 45.43 ? 1322 HOH A O 1 HETATM 8339 O O . HOH M 6 . ? 18.179 142.818 25.765 1.00 35.95 ? 1323 HOH A O 1 HETATM 8340 O O . HOH M 6 . ? 26.594 137.451 25.429 1.00 52.65 ? 1324 HOH A O 1 HETATM 8341 O O . HOH M 6 . ? 24.274 141.373 -8.233 1.00 22.87 ? 1325 HOH A O 1 HETATM 8342 O O . HOH M 6 . ? 24.945 145.389 -8.075 1.00 33.30 ? 1326 HOH A O 1 HETATM 8343 O O . HOH M 6 . ? 42.127 127.896 0.775 1.00 40.22 ? 1327 HOH A O 1 HETATM 8344 O O . HOH M 6 . ? 5.409 142.933 4.081 1.00 37.79 ? 1328 HOH A O 1 HETATM 8345 O O . HOH M 6 . ? -23.383 183.217 2.645 1.00 44.54 ? 1329 HOH A O 1 HETATM 8346 O O . HOH M 6 . ? 34.638 138.626 17.083 1.00 42.09 ? 1330 HOH A O 1 HETATM 8347 O O . HOH M 6 . ? -8.740 163.487 24.103 1.00 41.85 ? 1331 HOH A O 1 HETATM 8348 O O . HOH M 6 . ? 34.854 139.095 11.696 1.00 42.76 ? 1332 HOH A O 1 HETATM 8349 O O . HOH M 6 . ? -14.674 155.810 -1.019 1.00 41.40 ? 1333 HOH A O 1 HETATM 8350 O O . HOH M 6 . ? -16.954 154.380 -1.257 1.00 40.56 ? 1334 HOH A O 1 HETATM 8351 O O . HOH M 6 . ? -1.568 167.099 27.722 1.00 25.31 ? 1335 HOH A O 1 HETATM 8352 O O . HOH M 6 . ? -14.178 180.063 18.157 1.00 32.21 ? 1336 HOH A O 1 HETATM 8353 O O . HOH M 6 . ? -13.187 185.475 3.228 1.00 46.69 ? 1337 HOH A O 1 HETATM 8354 O O . HOH M 6 . ? 16.618 157.917 18.464 1.00 15.54 ? 1338 HOH A O 1 HETATM 8355 O O . HOH M 6 . ? 5.610 151.714 19.748 1.00 34.29 ? 1339 HOH A O 1 HETATM 8356 O O . HOH M 6 . ? -2.118 152.390 -19.974 1.00 48.31 ? 1340 HOH A O 1 HETATM 8357 O O . HOH M 6 . ? 13.739 174.870 -3.084 1.00 25.52 ? 1341 HOH A O 1 HETATM 8358 O O . HOH M 6 . ? -12.856 155.623 20.135 1.00 48.55 ? 1342 HOH A O 1 HETATM 8359 O O . HOH M 6 . ? 22.325 127.112 2.825 1.00 43.23 ? 1343 HOH A O 1 HETATM 8360 O O . HOH M 6 . ? 5.695 141.324 -6.852 1.00 40.02 ? 1344 HOH A O 1 HETATM 8361 O O . HOH M 6 . ? 12.041 178.945 -0.265 1.00 40.61 ? 1345 HOH A O 1 HETATM 8362 O O . HOH M 6 . ? -10.778 180.004 20.085 1.00 49.20 ? 1346 HOH A O 1 HETATM 8363 O O . HOH M 6 . ? 12.421 179.753 21.461 1.00 42.85 ? 1347 HOH A O 1 HETATM 8364 O O . HOH M 6 . ? -13.069 166.024 -16.589 1.00 42.97 ? 1348 HOH A O 1 HETATM 8365 O O . HOH M 6 . ? 31.450 124.580 -0.845 1.00 39.41 ? 1349 HOH A O 1 HETATM 8366 O O . HOH M 6 . ? 36.611 136.614 3.735 1.00 34.58 ? 1350 HOH A O 1 HETATM 8367 O O . HOH M 6 . ? -8.881 147.266 -5.497 1.00 45.54 ? 1351 HOH A O 1 HETATM 8368 O O . HOH M 6 . ? 25.986 152.633 -3.856 1.00 19.68 ? 1352 HOH A O 1 HETATM 8369 O O . HOH M 6 . ? 6.179 137.357 12.542 1.00 36.12 ? 1353 HOH A O 1 HETATM 8370 O O . HOH M 6 . ? 9.450 139.371 0.726 1.00 26.95 ? 1354 HOH A O 1 HETATM 8371 O O . HOH M 6 . ? -4.495 182.384 8.009 1.00 43.21 ? 1355 HOH A O 1 HETATM 8372 O O . HOH M 6 . ? -20.421 181.508 21.108 1.00 27.86 ? 1356 HOH A O 1 HETATM 8373 O O . HOH M 6 . ? 27.149 125.646 1.978 1.00 46.10 ? 1357 HOH A O 1 HETATM 8374 O O . HOH M 6 . ? -30.960 159.116 20.224 1.00 45.89 ? 1358 HOH A O 1 HETATM 8375 O O . HOH M 6 . ? -12.477 168.130 -17.874 1.00 45.51 ? 1359 HOH A O 1 HETATM 8376 O O . HOH M 6 . ? -7.037 168.127 24.638 1.00 22.79 ? 1360 HOH A O 1 HETATM 8377 O O . HOH M 6 . ? -11.986 181.476 18.543 1.00 33.31 ? 1361 HOH A O 1 HETATM 8378 O O . HOH M 6 . ? 2.575 144.306 1.835 1.00 44.19 ? 1362 HOH A O 1 HETATM 8379 O O . HOH M 6 . ? 32.126 138.786 15.402 1.00 26.20 ? 1363 HOH A O 1 HETATM 8380 O O . HOH M 6 . ? -8.921 171.768 -19.354 1.00 46.48 ? 1364 HOH A O 1 HETATM 8381 O O . HOH M 6 . ? 7.461 139.760 -1.184 1.00 50.71 ? 1365 HOH A O 1 HETATM 8382 O O . HOH M 6 . ? 18.705 129.161 1.864 1.00 39.90 ? 1366 HOH A O 1 HETATM 8383 O O . HOH M 6 . ? 27.826 128.016 15.218 1.00 42.26 ? 1367 HOH A O 1 HETATM 8384 O O . HOH M 6 . ? 16.806 157.561 27.201 1.00 45.76 ? 1368 HOH A O 1 HETATM 8385 O O . HOH M 6 . ? 6.840 139.857 -5.293 1.00 42.47 ? 1369 HOH A O 1 HETATM 8386 O O . HOH M 6 . ? 8.773 135.247 2.143 1.00 40.83 ? 1370 HOH A O 1 HETATM 8387 O O . HOH M 6 . ? 27.962 151.336 -5.343 1.00 47.23 ? 1371 HOH A O 1 HETATM 8388 O O . HOH M 6 . ? 38.791 125.172 1.722 1.00 38.89 ? 1372 HOH A O 1 HETATM 8389 O O . HOH M 6 . ? 32.580 137.546 13.202 1.00 30.36 ? 1373 HOH A O 1 HETATM 8390 O O . HOH M 6 . ? 33.141 144.038 -3.935 1.00 32.80 ? 1374 HOH A O 1 HETATM 8391 O O . HOH M 6 . ? -5.842 151.045 -19.995 1.00 48.89 ? 1375 HOH A O 1 HETATM 8392 O O . HOH M 6 . ? 7.289 140.074 -9.942 1.00 46.58 ? 1376 HOH A O 1 HETATM 8393 O O . HOH M 6 . ? 11.544 137.699 -12.400 1.00 45.80 ? 1377 HOH A O 1 HETATM 8394 O O . HOH M 6 . ? 10.841 135.629 -9.390 1.00 49.67 ? 1378 HOH A O 1 HETATM 8395 O O . HOH M 6 . ? 10.599 146.914 25.494 1.00 57.50 ? 1379 HOH A O 1 HETATM 8396 O O . HOH M 6 . ? 11.993 147.510 27.433 1.00 59.83 ? 1380 HOH A O 1 HETATM 8397 O O . HOH M 6 . ? 40.552 123.296 -0.169 1.00 42.77 ? 1381 HOH A O 1 HETATM 8398 O O . HOH M 6 . ? 38.541 121.835 0.046 1.00 48.56 ? 1382 HOH A O 1 HETATM 8399 O O . HOH N 6 . ? -26.273 176.840 -9.239 1.00 22.19 ? 1401 HOH C O 1 HETATM 8400 O O . HOH N 6 . ? -24.071 173.447 -8.819 1.00 34.15 ? 1402 HOH C O 1 HETATM 8401 O O . HOH N 6 . ? -28.639 175.012 11.618 1.00 35.43 ? 1403 HOH C O 1 HETATM 8402 O O . HOH N 6 . ? -14.216 177.850 -9.430 1.00 45.61 ? 1404 HOH C O 1 HETATM 8403 O O . HOH N 6 . ? -17.785 184.857 0.635 1.00 45.37 ? 1405 HOH C O 1 HETATM 8404 O O . HOH N 6 . ? -18.289 175.363 -4.075 1.00 18.66 ? 1406 HOH C O 1 HETATM 8405 O O . HOH N 6 . ? -18.651 180.532 -9.968 1.00 34.33 ? 1407 HOH C O 1 HETATM 8406 O O . HOH N 6 . ? -23.183 176.521 -10.887 1.00 22.29 ? 1408 HOH C O 1 HETATM 8407 O O . HOH N 6 . ? -11.296 182.528 0.222 1.00 31.44 ? 1409 HOH C O 1 HETATM 8408 O O . HOH N 6 . ? -12.470 180.345 1.736 1.00 22.40 ? 1410 HOH C O 1 HETATM 8409 O O . HOH N 6 . ? -19.566 184.443 -5.935 1.00 45.34 ? 1411 HOH C O 1 HETATM 8410 O O . HOH N 6 . ? -7.446 187.990 -7.799 1.00 56.90 ? 1412 HOH C O 1 HETATM 8411 O O . HOH N 6 . ? -21.037 180.515 -0.083 1.00 22.64 ? 1413 HOH C O 1 HETATM 8412 O O . HOH N 6 . ? -25.513 173.072 8.782 1.00 29.84 ? 1414 HOH C O 1 HETATM 8413 O O . HOH N 6 . ? -19.299 184.472 -1.658 1.00 52.33 ? 1415 HOH C O 1 HETATM 8414 O O . HOH N 6 . ? -14.233 176.125 -6.033 1.00 20.34 ? 1416 HOH C O 1 HETATM 8415 O O . HOH N 6 . ? -14.765 175.618 5.074 1.00 31.02 ? 1417 HOH C O 1 HETATM 8416 O O . HOH N 6 . ? -22.775 185.237 -9.262 1.00 43.74 ? 1418 HOH C O 1 HETATM 8417 O O . HOH N 6 . ? -25.343 178.333 4.824 1.00 34.22 ? 1419 HOH C O 1 HETATM 8418 O O . HOH N 6 . ? -27.599 177.489 5.428 1.00 51.53 ? 1420 HOH C O 1 HETATM 8419 O O . HOH N 6 . ? -17.347 183.798 -3.868 1.00 47.91 ? 1421 HOH C O 1 HETATM 8420 O O . HOH N 6 . ? -5.622 181.144 -7.839 1.00 31.40 ? 1422 HOH C O 1 HETATM 8421 O O . HOH N 6 . ? -7.988 176.364 -10.740 1.00 39.74 ? 1423 HOH C O 1 HETATM 8422 O O . HOH N 6 . ? -28.350 175.937 -2.541 1.00 40.33 ? 1424 HOH C O 1 HETATM 8423 O O . HOH N 6 . ? -13.473 183.296 4.300 1.00 38.45 ? 1425 HOH C O 1 HETATM 8424 O O . HOH N 6 . ? -10.100 180.723 -9.740 1.00 51.10 ? 1426 HOH C O 1 HETATM 8425 O O . HOH N 6 . ? -22.250 186.623 -7.641 1.00 52.60 ? 1427 HOH C O 1 HETATM 8426 O O . HOH N 6 . ? -17.664 186.646 2.080 1.00 55.92 ? 1428 HOH C O 1 HETATM 8427 O O . HOH N 6 . ? -22.245 182.795 0.640 1.00 52.38 ? 1429 HOH C O 1 HETATM 8428 O O . HOH N 6 . ? -22.117 172.392 -10.224 1.00 35.65 ? 1430 HOH C O 1 HETATM 8429 O O . HOH O 6 . ? -10.043 114.866 -21.833 1.00 30.37 ? 701 HOH B O 1 HETATM 8430 O O . HOH O 6 . ? -18.482 103.412 -4.984 1.00 25.85 ? 702 HOH B O 1 HETATM 8431 O O . HOH O 6 . ? 10.582 110.183 -27.368 1.00 49.58 ? 703 HOH B O 1 HETATM 8432 O O . HOH O 6 . ? -51.945 127.377 -11.129 1.00 30.92 ? 704 HOH B O 1 HETATM 8433 O O . HOH O 6 . ? -14.616 135.052 16.544 1.00 47.35 ? 705 HOH B O 1 HETATM 8434 O O . HOH O 6 . ? -36.901 113.592 9.273 1.00 25.61 ? 706 HOH B O 1 HETATM 8435 O O . HOH O 6 . ? -14.382 128.979 24.041 1.00 49.63 ? 707 HOH B O 1 HETATM 8436 O O . HOH O 6 . ? -36.710 114.061 -8.868 1.00 36.25 ? 708 HOH B O 1 HETATM 8437 O O . HOH O 6 . ? -48.042 126.561 -11.362 1.00 40.40 ? 709 HOH B O 1 HETATM 8438 O O . HOH O 6 . ? 2.655 101.163 -2.557 1.00 21.88 ? 710 HOH B O 1 HETATM 8439 O O . HOH O 6 . ? -31.820 117.266 -22.247 1.00 41.85 ? 711 HOH B O 1 HETATM 8440 O O . HOH O 6 . ? -10.840 108.537 7.300 1.00 27.85 ? 712 HOH B O 1 HETATM 8441 O O . HOH O 6 . ? 16.021 106.088 -9.486 1.00 43.71 ? 713 HOH B O 1 HETATM 8442 O O . HOH O 6 . ? -32.939 104.102 10.648 1.00 38.53 ? 714 HOH B O 1 HETATM 8443 O O . HOH O 6 . ? -35.842 142.176 6.385 1.00 45.07 ? 715 HOH B O 1 HETATM 8444 O O . HOH O 6 . ? -13.660 137.474 1.044 1.00 27.91 ? 716 HOH B O 1 HETATM 8445 O O . HOH O 6 . ? 6.507 126.003 4.685 1.00 21.84 ? 717 HOH B O 1 HETATM 8446 O O . HOH O 6 . ? -4.825 127.188 -3.706 1.00 31.41 ? 718 HOH B O 1 HETATM 8447 O O . HOH O 6 . ? -10.244 104.008 0.405 1.00 28.20 ? 719 HOH B O 1 HETATM 8448 O O . HOH O 6 . ? -18.497 125.063 -17.605 1.00 33.37 ? 720 HOH B O 1 HETATM 8449 O O . HOH O 6 . ? -49.353 136.141 -5.489 1.00 30.41 ? 721 HOH B O 1 HETATM 8450 O O . HOH O 6 . ? -25.697 104.071 -8.418 1.00 42.57 ? 722 HOH B O 1 HETATM 8451 O O . HOH O 6 . ? -15.476 108.621 9.978 1.00 47.98 ? 723 HOH B O 1 HETATM 8452 O O . HOH O 6 . ? 8.311 104.784 7.057 1.00 41.20 ? 724 HOH B O 1 HETATM 8453 O O . HOH O 6 . ? -8.101 113.642 -10.195 1.00 16.38 ? 725 HOH B O 1 HETATM 8454 O O . HOH O 6 . ? -32.531 108.259 -11.712 1.00 32.24 ? 726 HOH B O 1 HETATM 8455 O O . HOH O 6 . ? -25.932 143.448 -4.580 1.00 28.60 ? 727 HOH B O 1 HETATM 8456 O O . HOH O 6 . ? -30.882 108.557 -15.335 1.00 37.11 ? 728 HOH B O 1 HETATM 8457 O O . HOH O 6 . ? 13.690 103.115 -10.235 1.00 30.81 ? 729 HOH B O 1 HETATM 8458 O O . HOH O 6 . ? -31.792 115.732 -4.091 1.00 31.33 ? 730 HOH B O 1 HETATM 8459 O O . HOH O 6 . ? -21.052 119.305 19.504 1.00 30.64 ? 731 HOH B O 1 HETATM 8460 O O . HOH O 6 . ? -8.952 137.725 9.313 1.00 40.75 ? 732 HOH B O 1 HETATM 8461 O O . HOH O 6 . ? -42.898 135.664 -8.668 1.00 20.25 ? 733 HOH B O 1 HETATM 8462 O O . HOH O 6 . ? 0.698 132.584 -6.582 1.00 36.33 ? 734 HOH B O 1 HETATM 8463 O O . HOH O 6 . ? 1.884 99.058 1.964 1.00 52.21 ? 735 HOH B O 1 HETATM 8464 O O . HOH O 6 . ? -13.976 134.810 -7.642 1.00 29.96 ? 736 HOH B O 1 HETATM 8465 O O . HOH O 6 . ? -21.318 120.190 25.352 1.00 44.05 ? 737 HOH B O 1 HETATM 8466 O O . HOH O 6 . ? 22.995 116.769 -0.930 1.00 24.89 ? 738 HOH B O 1 HETATM 8467 O O . HOH O 6 . ? -31.088 116.454 -9.098 1.00 21.84 ? 739 HOH B O 1 HETATM 8468 O O . HOH O 6 . ? 10.771 129.554 12.062 1.00 35.00 ? 740 HOH B O 1 HETATM 8469 O O . HOH O 6 . ? -38.551 132.756 22.476 1.00 46.25 ? 741 HOH B O 1 HETATM 8470 O O . HOH O 6 . ? 2.247 132.276 -3.428 1.00 34.51 ? 742 HOH B O 1 HETATM 8471 O O . HOH O 6 . ? 16.432 117.727 14.043 1.00 29.99 ? 743 HOH B O 1 HETATM 8472 O O . HOH O 6 . ? 21.394 107.136 9.056 1.00 26.82 ? 744 HOH B O 1 HETATM 8473 O O . HOH O 6 . ? 2.920 122.608 0.050 1.00 14.84 ? 745 HOH B O 1 HETATM 8474 O O . HOH O 6 . ? -5.597 135.329 -0.464 1.00 34.14 ? 746 HOH B O 1 HETATM 8475 O O . HOH O 6 . ? -19.141 103.204 0.350 1.00 31.39 ? 747 HOH B O 1 HETATM 8476 O O . HOH O 6 . ? 3.212 125.768 -14.386 1.00 33.60 ? 748 HOH B O 1 HETATM 8477 O O . HOH O 6 . ? -21.299 118.702 11.798 1.00 20.05 ? 749 HOH B O 1 HETATM 8478 O O . HOH O 6 . ? -7.467 122.137 25.148 1.00 37.23 ? 750 HOH B O 1 HETATM 8479 O O . HOH O 6 . ? -16.795 142.762 8.414 1.00 43.90 ? 751 HOH B O 1 HETATM 8480 O O . HOH O 6 . ? 21.957 110.404 2.095 1.00 30.15 ? 752 HOH B O 1 HETATM 8481 O O . HOH O 6 . ? -17.982 138.780 12.133 1.00 37.99 ? 753 HOH B O 1 HETATM 8482 O O . HOH O 6 . ? -16.031 106.982 -6.344 1.00 22.44 ? 754 HOH B O 1 HETATM 8483 O O . HOH O 6 . ? 15.267 131.539 -9.522 1.00 28.79 ? 755 HOH B O 1 HETATM 8484 O O . HOH O 6 . ? -13.580 115.999 23.199 1.00 32.49 ? 756 HOH B O 1 HETATM 8485 O O . HOH O 6 . ? -43.524 139.132 -15.257 1.00 24.03 ? 757 HOH B O 1 HETATM 8486 O O . HOH O 6 . ? -13.369 139.960 0.066 1.00 33.23 ? 758 HOH B O 1 HETATM 8487 O O . HOH O 6 . ? -10.409 133.733 14.786 1.00 39.39 ? 759 HOH B O 1 HETATM 8488 O O . HOH O 6 . ? -11.559 119.293 -20.635 1.00 28.01 ? 760 HOH B O 1 HETATM 8489 O O . HOH O 6 . ? -54.979 131.553 -6.922 1.00 33.70 ? 761 HOH B O 1 HETATM 8490 O O . HOH O 6 . ? 0.512 117.087 15.445 1.00 28.76 ? 762 HOH B O 1 HETATM 8491 O O . HOH O 6 . ? -21.043 123.582 22.455 1.00 28.97 ? 763 HOH B O 1 HETATM 8492 O O . HOH O 6 . ? -16.897 109.602 -3.134 1.00 15.67 ? 764 HOH B O 1 HETATM 8493 O O . HOH O 6 . ? -12.072 105.472 4.972 1.00 30.15 ? 765 HOH B O 1 HETATM 8494 O O . HOH O 6 . ? -24.659 139.893 8.889 1.00 30.13 ? 766 HOH B O 1 HETATM 8495 O O . HOH O 6 . ? -10.288 115.822 2.848 1.00 12.18 ? 767 HOH B O 1 HETATM 8496 O O . HOH O 6 . ? -3.898 129.876 3.356 1.00 31.08 ? 768 HOH B O 1 HETATM 8497 O O . HOH O 6 . ? -10.283 115.603 -18.525 1.00 29.48 ? 769 HOH B O 1 HETATM 8498 O O . HOH O 6 . ? -35.601 115.680 14.284 1.00 38.98 ? 770 HOH B O 1 HETATM 8499 O O . HOH O 6 . ? -21.122 138.921 6.384 1.00 33.32 ? 771 HOH B O 1 HETATM 8500 O O . HOH O 6 . ? -16.327 136.765 16.085 1.00 35.89 ? 772 HOH B O 1 HETATM 8501 O O . HOH O 6 . ? -35.372 117.917 -15.751 1.00 33.30 ? 773 HOH B O 1 HETATM 8502 O O . HOH O 6 . ? -34.534 135.692 -9.061 1.00 33.77 ? 774 HOH B O 1 HETATM 8503 O O . HOH O 6 . ? -34.008 126.292 10.810 1.00 22.83 ? 775 HOH B O 1 HETATM 8504 O O . HOH O 6 . ? -32.843 137.028 -13.320 1.00 36.91 ? 776 HOH B O 1 HETATM 8505 O O . HOH O 6 . ? 9.372 110.112 10.592 1.00 24.41 ? 777 HOH B O 1 HETATM 8506 O O . HOH O 6 . ? 26.979 116.798 3.772 1.00 29.10 ? 778 HOH B O 1 HETATM 8507 O O . HOH O 6 . ? 0.367 125.253 16.383 1.00 34.51 ? 779 HOH B O 1 HETATM 8508 O O . HOH O 6 . ? 19.827 113.711 -14.477 1.00 36.87 ? 780 HOH B O 1 HETATM 8509 O O . HOH O 6 . ? -25.158 138.900 2.540 1.00 19.87 ? 781 HOH B O 1 HETATM 8510 O O . HOH O 6 . ? -34.167 121.056 1.880 1.00 28.02 ? 782 HOH B O 1 HETATM 8511 O O . HOH O 6 . ? 14.714 125.941 -1.074 1.00 17.24 ? 783 HOH B O 1 HETATM 8512 O O . HOH O 6 . ? -16.595 119.052 -20.630 1.00 28.45 ? 784 HOH B O 1 HETATM 8513 O O . HOH O 6 . ? -42.676 136.371 -0.452 1.00 21.25 ? 785 HOH B O 1 HETATM 8514 O O . HOH O 6 . ? -0.261 131.154 -0.642 1.00 24.40 ? 786 HOH B O 1 HETATM 8515 O O . HOH O 6 . ? -8.912 111.961 19.176 1.00 45.88 ? 787 HOH B O 1 HETATM 8516 O O . HOH O 6 . ? -12.522 109.823 7.687 1.00 37.08 ? 788 HOH B O 1 HETATM 8517 O O . HOH O 6 . ? 3.222 131.432 -11.694 1.00 35.56 ? 789 HOH B O 1 HETATM 8518 O O . HOH O 6 . ? -27.348 142.579 9.485 1.00 33.83 ? 790 HOH B O 1 HETATM 8519 O O . HOH O 6 . ? -23.258 124.021 11.235 1.00 23.83 ? 791 HOH B O 1 HETATM 8520 O O . HOH O 6 . ? 1.227 128.875 -14.028 1.00 39.67 ? 792 HOH B O 1 HETATM 8521 O O . HOH O 6 . ? -7.106 118.152 16.654 1.00 20.23 ? 793 HOH B O 1 HETATM 8522 O O . HOH O 6 . ? 15.231 110.084 11.987 1.00 25.73 ? 794 HOH B O 1 HETATM 8523 O O . HOH O 6 . ? -21.121 136.375 -14.596 1.00 33.81 ? 795 HOH B O 1 HETATM 8524 O O . HOH O 6 . ? -34.107 130.820 -18.873 1.00 31.37 ? 796 HOH B O 1 HETATM 8525 O O . HOH O 6 . ? 21.113 111.182 -2.212 1.00 28.21 ? 797 HOH B O 1 HETATM 8526 O O . HOH O 6 . ? -28.439 108.691 12.452 1.00 30.97 ? 798 HOH B O 1 HETATM 8527 O O . HOH O 6 . ? -5.053 110.825 4.895 1.00 13.11 ? 799 HOH B O 1 HETATM 8528 O O . HOH O 6 . ? 18.821 115.947 -11.324 1.00 26.48 ? 800 HOH B O 1 HETATM 8529 O O . HOH O 6 . ? -30.246 122.841 7.416 1.00 20.14 ? 801 HOH B O 1 HETATM 8530 O O . HOH O 6 . ? -29.101 117.068 20.101 1.00 41.67 ? 802 HOH B O 1 HETATM 8531 O O . HOH O 6 . ? -21.330 122.136 11.594 1.00 19.74 ? 803 HOH B O 1 HETATM 8532 O O . HOH O 6 . ? -20.070 121.409 -18.529 1.00 37.36 ? 804 HOH B O 1 HETATM 8533 O O . HOH O 6 . ? 10.110 104.583 -12.446 1.00 16.23 ? 805 HOH B O 1 HETATM 8534 O O . HOH O 6 . ? -16.268 118.322 8.241 1.00 23.88 ? 806 HOH B O 1 HETATM 8535 O O . HOH O 6 . ? -11.170 109.099 -22.747 1.00 42.82 ? 807 HOH B O 1 HETATM 8536 O O . HOH O 6 . ? -10.270 120.388 -17.109 1.00 32.96 ? 808 HOH B O 1 HETATM 8537 O O . HOH O 6 . ? 7.785 120.260 -14.887 1.00 16.10 ? 809 HOH B O 1 HETATM 8538 O O . HOH O 6 . ? -32.771 129.342 23.144 1.00 37.40 ? 810 HOH B O 1 HETATM 8539 O O . HOH O 6 . ? -2.585 121.780 -16.611 1.00 41.44 ? 811 HOH B O 1 HETATM 8540 O O . HOH O 6 . ? -35.509 122.793 18.749 1.00 38.78 ? 812 HOH B O 1 HETATM 8541 O O . HOH O 6 . ? -2.078 124.186 17.606 1.00 29.12 ? 813 HOH B O 1 HETATM 8542 O O . HOH O 6 . ? -30.768 123.339 18.216 1.00 24.18 ? 814 HOH B O 1 HETATM 8543 O O . HOH O 6 . ? -11.893 137.939 9.996 1.00 34.92 ? 815 HOH B O 1 HETATM 8544 O O . HOH O 6 . ? -40.067 126.117 -13.853 1.00 27.38 ? 816 HOH B O 1 HETATM 8545 O O . HOH O 6 . ? -26.832 127.977 11.577 1.00 27.02 ? 817 HOH B O 1 HETATM 8546 O O . HOH O 6 . ? -23.650 137.761 18.578 1.00 38.68 ? 818 HOH B O 1 HETATM 8547 O O . HOH O 6 . ? -25.834 118.232 3.899 1.00 14.92 ? 819 HOH B O 1 HETATM 8548 O O . HOH O 6 . ? 15.049 131.292 -15.093 1.00 23.82 ? 820 HOH B O 1 HETATM 8549 O O . HOH O 6 . ? -24.912 128.679 21.014 1.00 38.72 ? 821 HOH B O 1 HETATM 8550 O O . HOH O 6 . ? 0.915 103.225 2.551 1.00 33.42 ? 822 HOH B O 1 HETATM 8551 O O . HOH O 6 . ? -20.698 104.981 -5.963 1.00 19.00 ? 823 HOH B O 1 HETATM 8552 O O . HOH O 6 . ? 4.448 124.198 12.428 1.00 16.00 ? 824 HOH B O 1 HETATM 8553 O O . HOH O 6 . ? -36.092 124.415 -13.241 1.00 28.49 ? 825 HOH B O 1 HETATM 8554 O O . HOH O 6 . ? 9.288 126.026 -18.680 1.00 29.45 ? 826 HOH B O 1 HETATM 8555 O O . HOH O 6 . ? -28.203 136.566 -5.255 1.00 19.51 ? 827 HOH B O 1 HETATM 8556 O O . HOH O 6 . ? -7.695 110.950 16.847 1.00 28.23 ? 828 HOH B O 1 HETATM 8557 O O . HOH O 6 . ? -11.328 99.543 -3.818 1.00 14.58 ? 829 HOH B O 1 HETATM 8558 O O . HOH O 6 . ? -10.574 122.059 5.196 1.00 14.50 ? 830 HOH B O 1 HETATM 8559 O O . HOH O 6 . ? -12.242 118.118 10.312 1.00 22.89 ? 831 HOH B O 1 HETATM 8560 O O . HOH O 6 . ? -0.671 117.593 -16.183 1.00 35.19 ? 832 HOH B O 1 HETATM 8561 O O . HOH O 6 . ? -3.202 125.795 5.135 1.00 19.13 ? 833 HOH B O 1 HETATM 8562 O O . HOH O 6 . ? -23.997 123.448 25.607 1.00 48.46 ? 834 HOH B O 1 HETATM 8563 O O . HOH O 6 . ? -16.258 134.991 12.873 1.00 31.81 ? 835 HOH B O 1 HETATM 8564 O O . HOH O 6 . ? 4.500 103.450 5.482 1.00 32.99 ? 836 HOH B O 1 HETATM 8565 O O . HOH O 6 . ? 4.267 120.994 -18.125 1.00 34.02 ? 837 HOH B O 1 HETATM 8566 O O . HOH O 6 . ? -22.335 129.960 -12.814 1.00 17.50 ? 838 HOH B O 1 HETATM 8567 O O . HOH O 6 . ? -17.748 136.256 -8.311 1.00 28.80 ? 839 HOH B O 1 HETATM 8568 O O . HOH O 6 . ? -24.423 126.513 4.933 1.00 16.29 ? 840 HOH B O 1 HETATM 8569 O O . HOH O 6 . ? 13.328 112.922 -1.086 1.00 12.49 ? 841 HOH B O 1 HETATM 8570 O O . HOH O 6 . ? -18.974 107.418 -5.009 1.00 25.38 ? 842 HOH B O 1 HETATM 8571 O O . HOH O 6 . ? -19.596 140.242 -1.852 1.00 27.75 ? 843 HOH B O 1 HETATM 8572 O O . HOH O 6 . ? -13.279 131.318 -8.525 1.00 35.87 ? 844 HOH B O 1 HETATM 8573 O O . HOH O 6 . ? -0.006 107.192 4.749 1.00 17.15 ? 845 HOH B O 1 HETATM 8574 O O . HOH O 6 . ? 22.218 120.084 0.048 1.00 34.21 ? 846 HOH B O 1 HETATM 8575 O O . HOH O 6 . ? -11.437 109.424 18.748 1.00 31.50 ? 847 HOH B O 1 HETATM 8576 O O . HOH O 6 . ? 15.665 129.170 -6.656 1.00 28.19 ? 848 HOH B O 1 HETATM 8577 O O . HOH O 6 . ? 6.173 115.946 9.338 1.00 15.81 ? 849 HOH B O 1 HETATM 8578 O O . HOH O 6 . ? 11.329 106.399 4.648 1.00 26.09 ? 850 HOH B O 1 HETATM 8579 O O . HOH O 6 . ? -29.122 110.342 -16.220 1.00 34.26 ? 851 HOH B O 1 HETATM 8580 O O . HOH O 6 . ? -5.847 101.765 0.148 1.00 20.10 ? 852 HOH B O 1 HETATM 8581 O O . HOH O 6 . ? -17.719 120.020 5.127 1.00 14.32 ? 853 HOH B O 1 HETATM 8582 O O . HOH O 6 . ? 1.282 110.436 10.995 1.00 15.76 ? 854 HOH B O 1 HETATM 8583 O O . HOH O 6 . ? -14.117 116.887 9.234 1.00 20.95 ? 855 HOH B O 1 HETATM 8584 O O . HOH O 6 . ? 11.967 125.359 19.913 1.00 29.92 ? 856 HOH B O 1 HETATM 8585 O O . HOH O 6 . ? -23.061 134.713 -5.629 1.00 18.10 ? 857 HOH B O 1 HETATM 8586 O O . HOH O 6 . ? 7.859 117.029 13.628 1.00 23.91 ? 858 HOH B O 1 HETATM 8587 O O . HOH O 6 . ? 1.429 125.893 6.439 1.00 15.16 ? 859 HOH B O 1 HETATM 8588 O O . HOH O 6 . ? -8.866 128.644 -11.156 1.00 29.87 ? 860 HOH B O 1 HETATM 8589 O O . HOH O 6 . ? -43.345 123.707 2.368 1.00 31.05 ? 861 HOH B O 1 HETATM 8590 O O . HOH O 6 . ? 12.143 117.361 12.709 1.00 21.92 ? 862 HOH B O 1 HETATM 8591 O O . HOH O 6 . ? -19.514 125.199 19.585 1.00 37.24 ? 863 HOH B O 1 HETATM 8592 O O . HOH O 6 . ? -32.871 131.667 5.907 1.00 19.51 ? 864 HOH B O 1 HETATM 8593 O O . HOH O 6 . ? 18.336 108.157 11.120 1.00 31.30 ? 865 HOH B O 1 HETATM 8594 O O . HOH O 6 . ? -18.790 123.387 11.135 1.00 19.05 ? 866 HOH B O 1 HETATM 8595 O O . HOH O 6 . ? 2.382 129.833 2.049 1.00 24.93 ? 867 HOH B O 1 HETATM 8596 O O . HOH O 6 . ? -23.768 107.705 -19.670 1.00 35.17 ? 868 HOH B O 1 HETATM 8597 O O . HOH O 6 . ? 2.290 118.844 -16.977 1.00 26.04 ? 869 HOH B O 1 HETATM 8598 O O . HOH O 6 . ? -43.897 122.505 -10.264 1.00 32.68 ? 870 HOH B O 1 HETATM 8599 O O . HOH O 6 . ? -36.964 143.514 -8.734 1.00 42.76 ? 871 HOH B O 1 HETATM 8600 O O . HOH O 6 . ? -38.181 121.944 -0.580 1.00 23.82 ? 872 HOH B O 1 HETATM 8601 O O . HOH O 6 . ? -25.428 130.391 -5.260 1.00 14.07 ? 873 HOH B O 1 HETATM 8602 O O . HOH O 6 . ? 1.956 108.157 6.549 1.00 18.67 ? 874 HOH B O 1 HETATM 8603 O O . HOH O 6 . ? -1.387 130.572 -8.120 1.00 30.95 ? 875 HOH B O 1 HETATM 8604 O O . HOH O 6 . ? 18.112 108.286 -2.474 1.00 33.30 ? 876 HOH B O 1 HETATM 8605 O O . HOH O 6 . ? -10.164 133.636 -9.979 1.00 37.99 ? 877 HOH B O 1 HETATM 8606 O O . HOH O 6 . ? 7.314 119.065 -20.947 1.00 35.36 ? 878 HOH B O 1 HETATM 8607 O O . HOH O 6 . ? 26.544 113.907 14.068 1.00 36.37 ? 879 HOH B O 1 HETATM 8608 O O . HOH O 6 . ? 9.341 124.700 19.239 1.00 29.03 ? 880 HOH B O 1 HETATM 8609 O O . HOH O 6 . ? 18.630 128.327 9.145 1.00 31.12 ? 881 HOH B O 1 HETATM 8610 O O . HOH O 6 . ? -2.779 107.990 4.912 1.00 15.03 ? 882 HOH B O 1 HETATM 8611 O O . HOH O 6 . ? -24.260 139.816 -10.286 1.00 24.37 ? 883 HOH B O 1 HETATM 8612 O O . HOH O 6 . ? -18.052 118.379 -2.146 1.00 10.65 ? 884 HOH B O 1 HETATM 8613 O O . HOH O 6 . ? 17.117 128.628 -8.819 1.00 20.78 ? 885 HOH B O 1 HETATM 8614 O O . HOH O 6 . ? 9.748 127.062 -9.569 1.00 16.02 ? 886 HOH B O 1 HETATM 8615 O O . HOH O 6 . ? -13.454 119.458 28.394 1.00 45.75 ? 887 HOH B O 1 HETATM 8616 O O . HOH O 6 . ? 9.621 126.199 14.657 1.00 22.47 ? 888 HOH B O 1 HETATM 8617 O O . HOH O 6 . ? -9.159 109.481 -9.943 1.00 13.66 ? 889 HOH B O 1 HETATM 8618 O O . HOH O 6 . ? -2.768 102.944 -7.784 1.00 15.34 ? 890 HOH B O 1 HETATM 8619 O O . HOH O 6 . ? -33.783 124.147 21.336 1.00 35.31 ? 891 HOH B O 1 HETATM 8620 O O . HOH O 6 . ? -43.083 124.238 -3.243 1.00 27.32 ? 892 HOH B O 1 HETATM 8621 O O . HOH O 6 . ? -37.771 135.746 -13.119 1.00 31.19 ? 893 HOH B O 1 HETATM 8622 O O . HOH O 6 . ? -4.018 113.061 15.483 1.00 19.20 ? 894 HOH B O 1 HETATM 8623 O O . HOH O 6 . ? 3.659 122.285 15.458 1.00 27.32 ? 895 HOH B O 1 HETATM 8624 O O . HOH O 6 . ? -24.852 121.524 -20.004 1.00 17.82 ? 896 HOH B O 1 HETATM 8625 O O . HOH O 6 . ? -33.552 141.651 5.095 1.00 29.52 ? 897 HOH B O 1 HETATM 8626 O O . HOH O 6 . ? -15.614 116.669 25.476 1.00 41.07 ? 898 HOH B O 1 HETATM 8627 O O . HOH O 6 . ? -27.502 108.791 -15.235 1.00 40.66 ? 899 HOH B O 1 HETATM 8628 O O . HOH O 6 . ? 13.985 104.349 -8.328 1.00 33.10 ? 900 HOH B O 1 HETATM 8629 O O . HOH O 6 . ? -38.651 128.794 -1.439 1.00 34.16 ? 901 HOH B O 1 HETATM 8630 O O . HOH O 6 . ? -10.643 113.973 -14.444 1.00 18.21 ? 902 HOH B O 1 HETATM 8631 O O . HOH O 6 . ? -7.615 123.724 -15.062 1.00 24.26 ? 903 HOH B O 1 HETATM 8632 O O . HOH O 6 . ? 20.862 120.462 2.355 1.00 18.01 ? 904 HOH B O 1 HETATM 8633 O O . HOH O 6 . ? 0.181 101.269 -0.523 1.00 25.49 ? 905 HOH B O 1 HETATM 8634 O O . HOH O 6 . ? 9.523 129.379 -7.950 1.00 20.25 ? 906 HOH B O 1 HETATM 8635 O O . HOH O 6 . ? -16.425 125.349 19.953 1.00 29.96 ? 907 HOH B O 1 HETATM 8636 O O . HOH O 6 . ? -19.837 127.561 -14.354 1.00 23.89 ? 908 HOH B O 1 HETATM 8637 O O . HOH O 6 . ? -0.595 123.145 -16.953 1.00 33.39 ? 909 HOH B O 1 HETATM 8638 O O . HOH O 6 . ? -17.600 142.517 0.884 1.00 35.29 ? 910 HOH B O 1 HETATM 8639 O O . HOH O 6 . ? 4.174 115.644 13.703 1.00 19.21 ? 911 HOH B O 1 HETATM 8640 O O . HOH O 6 . ? -25.769 118.046 0.996 1.00 14.97 ? 912 HOH B O 1 HETATM 8641 O O . HOH O 6 . ? -40.363 118.109 -6.211 1.00 38.28 ? 913 HOH B O 1 HETATM 8642 O O . HOH O 6 . ? 4.555 131.897 -5.061 1.00 19.43 ? 914 HOH B O 1 HETATM 8643 O O . HOH O 6 . ? -23.364 124.445 6.657 1.00 16.28 ? 915 HOH B O 1 HETATM 8644 O O . HOH O 6 . ? 9.610 130.968 1.741 1.00 26.42 ? 916 HOH B O 1 HETATM 8645 O O . HOH O 6 . ? -16.384 121.897 -11.981 1.00 11.77 ? 917 HOH B O 1 HETATM 8646 O O . HOH O 6 . ? 12.963 102.503 -1.558 1.00 25.93 ? 918 HOH B O 1 HETATM 8647 O O . HOH O 6 . ? -27.161 134.437 21.777 1.00 41.24 ? 919 HOH B O 1 HETATM 8648 O O . HOH O 6 . ? 23.889 120.465 10.678 1.00 31.98 ? 920 HOH B O 1 HETATM 8649 O O . HOH O 6 . ? -37.700 140.776 6.117 1.00 35.52 ? 921 HOH B O 1 HETATM 8650 O O . HOH O 6 . ? -0.463 118.284 7.937 1.00 19.00 ? 922 HOH B O 1 HETATM 8651 O O . HOH O 6 . ? -19.953 131.391 -12.700 1.00 19.76 ? 923 HOH B O 1 HETATM 8652 O O . HOH O 6 . ? -23.783 132.364 -4.284 1.00 14.91 ? 924 HOH B O 1 HETATM 8653 O O . HOH O 6 . ? -26.293 104.318 -2.154 1.00 38.92 ? 925 HOH B O 1 HETATM 8654 O O . HOH O 6 . ? -40.602 146.061 -9.255 1.00 34.81 ? 926 HOH B O 1 HETATM 8655 O O . HOH O 6 . ? -3.415 123.019 4.342 1.00 17.36 ? 927 HOH B O 1 HETATM 8656 O O . HOH O 6 . ? -22.342 145.761 0.183 1.00 41.14 ? 928 HOH B O 1 HETATM 8657 O O . HOH O 6 . ? -3.193 123.270 -8.060 1.00 13.56 ? 929 HOH B O 1 HETATM 8658 O O . HOH O 6 . ? -24.455 139.517 16.528 1.00 33.85 ? 930 HOH B O 1 HETATM 8659 O O . HOH O 6 . ? -24.890 126.677 12.730 1.00 36.10 ? 931 HOH B O 1 HETATM 8660 O O . HOH O 6 . ? 11.966 130.656 -8.056 1.00 20.39 ? 932 HOH B O 1 HETATM 8661 O O . HOH O 6 . ? 5.981 100.246 -1.589 1.00 27.04 ? 933 HOH B O 1 HETATM 8662 O O . HOH O 6 . ? -15.330 107.803 -2.285 1.00 34.14 ? 934 HOH B O 1 HETATM 8663 O O . HOH O 6 . ? -8.826 107.537 4.110 1.00 30.51 ? 935 HOH B O 1 HETATM 8664 O O . HOH O 6 . ? -38.708 150.681 -3.534 1.00 43.01 ? 936 HOH B O 1 HETATM 8665 O O . HOH O 6 . ? 15.658 112.510 -12.431 1.00 19.59 ? 937 HOH B O 1 HETATM 8666 O O . HOH O 6 . ? -24.703 124.536 13.634 1.00 34.47 ? 938 HOH B O 1 HETATM 8667 O O . HOH O 6 . ? -39.662 119.932 -9.637 1.00 33.25 ? 939 HOH B O 1 HETATM 8668 O O . HOH O 6 . ? -1.544 128.148 13.966 1.00 28.52 ? 940 HOH B O 1 HETATM 8669 O O . HOH O 6 . ? 8.132 106.317 2.406 1.00 15.64 ? 941 HOH B O 1 HETATM 8670 O O . HOH O 6 . ? 3.294 111.253 -15.813 1.00 41.55 ? 942 HOH B O 1 HETATM 8671 O O . HOH O 6 . ? -15.017 127.466 13.416 1.00 19.97 ? 943 HOH B O 1 HETATM 8672 O O . HOH O 6 . ? -0.937 129.346 -10.453 1.00 24.03 ? 944 HOH B O 1 HETATM 8673 O O . HOH O 6 . ? -47.626 121.772 -6.622 1.00 47.99 ? 945 HOH B O 1 HETATM 8674 O O . HOH O 6 . ? -20.389 114.996 -15.380 1.00 13.26 ? 946 HOH B O 1 HETATM 8675 O O . HOH O 6 . ? -40.884 130.672 -2.634 1.00 24.57 ? 947 HOH B O 1 HETATM 8676 O O . HOH O 6 . ? -15.236 110.228 12.635 1.00 25.21 ? 948 HOH B O 1 HETATM 8677 O O . HOH O 6 . ? -2.754 125.737 19.558 1.00 37.29 ? 949 HOH B O 1 HETATM 8678 O O . HOH O 6 . ? -30.518 126.168 -8.543 1.00 14.09 ? 950 HOH B O 1 HETATM 8679 O O . HOH O 6 . ? -27.175 108.799 -10.717 1.00 20.54 ? 951 HOH B O 1 HETATM 8680 O O . HOH O 6 . ? -15.327 105.663 4.285 1.00 21.63 ? 952 HOH B O 1 HETATM 8681 O O . HOH O 6 . ? -42.204 127.952 -13.629 1.00 24.66 ? 953 HOH B O 1 HETATM 8682 O O . HOH O 6 . ? -7.347 130.876 6.952 1.00 20.77 ? 954 HOH B O 1 HETATM 8683 O O . HOH O 6 . ? 11.260 119.385 -21.008 1.00 41.08 ? 955 HOH B O 1 HETATM 8684 O O . HOH O 6 . ? -15.500 126.583 10.781 1.00 16.69 ? 956 HOH B O 1 HETATM 8685 O O . HOH O 6 . ? -23.803 133.365 -14.844 1.00 29.40 ? 957 HOH B O 1 HETATM 8686 O O . HOH O 6 . ? 10.085 131.295 -5.147 1.00 36.85 ? 958 HOH B O 1 HETATM 8687 O O . HOH O 6 . ? -31.614 121.754 5.239 1.00 19.46 ? 959 HOH B O 1 HETATM 8688 O O . HOH O 6 . ? -9.949 120.152 2.580 1.00 13.37 ? 960 HOH B O 1 HETATM 8689 O O . HOH O 6 . ? -6.933 107.606 5.136 1.00 30.58 ? 961 HOH B O 1 HETATM 8690 O O . HOH O 6 . ? -28.304 120.336 21.241 1.00 41.31 ? 962 HOH B O 1 HETATM 8691 O O . HOH O 6 . ? -19.731 139.971 -9.163 1.00 44.16 ? 963 HOH B O 1 HETATM 8692 O O . HOH O 6 . ? -13.920 111.814 -24.128 1.00 35.47 ? 964 HOH B O 1 HETATM 8693 O O . HOH O 6 . ? -28.941 120.840 11.600 1.00 21.45 ? 965 HOH B O 1 HETATM 8694 O O . HOH O 6 . ? 21.661 125.143 -10.950 1.00 30.48 ? 966 HOH B O 1 HETATM 8695 O O . HOH O 6 . ? 14.945 128.307 3.133 1.00 21.64 ? 967 HOH B O 1 HETATM 8696 O O . HOH O 6 . ? -10.515 115.558 21.140 1.00 26.58 ? 968 HOH B O 1 HETATM 8697 O O . HOH O 6 . ? 14.866 122.507 22.969 1.00 45.01 ? 969 HOH B O 1 HETATM 8698 O O . HOH O 6 . ? -32.126 126.677 -16.146 1.00 18.20 ? 970 HOH B O 1 HETATM 8699 O O . HOH O 6 . ? -41.199 121.592 0.273 1.00 39.35 ? 971 HOH B O 1 HETATM 8700 O O . HOH O 6 . ? 12.962 112.582 -18.887 1.00 40.85 ? 972 HOH B O 1 HETATM 8701 O O . HOH O 6 . ? -17.281 135.609 -0.714 1.00 19.99 ? 973 HOH B O 1 HETATM 8702 O O . HOH O 6 . ? -29.650 113.682 -7.389 1.00 31.54 ? 974 HOH B O 1 HETATM 8703 O O . HOH O 6 . ? 18.410 107.629 2.687 1.00 28.99 ? 975 HOH B O 1 HETATM 8704 O O . HOH O 6 . ? -2.642 114.253 17.473 1.00 31.84 ? 976 HOH B O 1 HETATM 8705 O O . HOH O 6 . ? -14.269 125.389 -18.031 1.00 39.75 ? 977 HOH B O 1 HETATM 8706 O O . HOH O 6 . ? -33.825 131.759 8.555 1.00 21.87 ? 978 HOH B O 1 HETATM 8707 O O . HOH O 6 . ? -13.840 105.857 -2.428 1.00 24.54 ? 979 HOH B O 1 HETATM 8708 O O . HOH O 6 . ? -22.292 141.692 9.900 1.00 43.35 ? 980 HOH B O 1 HETATM 8709 O O . HOH O 6 . ? -28.158 116.912 1.441 1.00 20.61 ? 981 HOH B O 1 HETATM 8710 O O . HOH O 6 . ? -29.489 115.803 -5.656 1.00 25.78 ? 982 HOH B O 1 HETATM 8711 O O . HOH O 6 . ? -37.279 119.701 -10.993 1.00 32.15 ? 983 HOH B O 1 HETATM 8712 O O . HOH O 6 . ? -15.379 129.529 20.393 1.00 33.49 ? 984 HOH B O 1 HETATM 8713 O O . HOH O 6 . ? 0.593 106.714 -11.019 1.00 24.47 ? 985 HOH B O 1 HETATM 8714 O O . HOH O 6 . ? -30.593 123.818 -19.896 1.00 23.42 ? 986 HOH B O 1 HETATM 8715 O O . HOH O 6 . ? -15.140 122.654 -6.728 1.00 12.04 ? 987 HOH B O 1 HETATM 8716 O O . HOH O 6 . ? -21.928 111.487 13.861 1.00 20.57 ? 988 HOH B O 1 HETATM 8717 O O . HOH O 6 . ? -6.053 134.080 1.957 1.00 32.84 ? 989 HOH B O 1 HETATM 8718 O O . HOH O 6 . ? -29.832 132.149 -6.982 1.00 18.82 ? 990 HOH B O 1 HETATM 8719 O O . HOH O 6 . ? -16.627 109.524 -24.924 1.00 32.14 ? 991 HOH B O 1 HETATM 8720 O O . HOH O 6 . ? -39.535 137.607 -16.721 1.00 33.80 ? 992 HOH B O 1 HETATM 8721 O O . HOH O 6 . ? -47.707 133.072 -8.034 1.00 29.33 ? 993 HOH B O 1 HETATM 8722 O O . HOH O 6 . ? -24.423 110.002 10.687 1.00 27.15 ? 994 HOH B O 1 HETATM 8723 O O . HOH O 6 . ? 1.097 99.402 -4.432 1.00 18.42 ? 995 HOH B O 1 HETATM 8724 O O . HOH O 6 . ? 9.876 128.604 -11.983 1.00 24.48 ? 996 HOH B O 1 HETATM 8725 O O . HOH O 6 . ? -3.668 128.940 20.988 1.00 33.60 ? 997 HOH B O 1 HETATM 8726 O O . HOH O 6 . ? 18.081 116.081 15.744 1.00 37.06 ? 998 HOH B O 1 HETATM 8727 O O . HOH O 6 . ? 14.634 118.282 -16.599 1.00 23.15 ? 999 HOH B O 1 HETATM 8728 O O . HOH O 6 . ? -25.997 140.910 5.759 1.00 28.92 ? 1000 HOH B O 1 HETATM 8729 O O . HOH O 6 . ? 15.506 107.023 4.875 1.00 29.66 ? 1001 HOH B O 1 HETATM 8730 O O . HOH O 6 . ? -32.270 133.125 -17.764 1.00 24.33 ? 1002 HOH B O 1 HETATM 8731 O O . HOH O 6 . ? -31.085 122.567 10.280 1.00 27.56 ? 1003 HOH B O 1 HETATM 8732 O O . HOH O 6 . ? -12.235 105.046 -1.365 1.00 23.49 ? 1004 HOH B O 1 HETATM 8733 O O . HOH O 6 . ? -9.929 134.523 12.094 1.00 36.09 ? 1005 HOH B O 1 HETATM 8734 O O . HOH O 6 . ? -34.860 117.952 -1.412 1.00 27.10 ? 1006 HOH B O 1 HETATM 8735 O O . HOH O 6 . ? -26.788 109.149 16.235 1.00 28.71 ? 1007 HOH B O 1 HETATM 8736 O O . HOH O 6 . ? 8.462 127.742 -14.366 1.00 28.58 ? 1008 HOH B O 1 HETATM 8737 O O . HOH O 6 . ? 3.999 126.798 5.677 1.00 16.32 ? 1009 HOH B O 1 HETATM 8738 O O . HOH O 6 . ? -13.066 113.287 -27.264 1.00 33.30 ? 1010 HOH B O 1 HETATM 8739 O O . HOH O 6 . ? -23.857 130.941 -20.572 1.00 32.41 ? 1011 HOH B O 1 HETATM 8740 O O . HOH O 6 . ? -12.337 104.022 2.361 1.00 24.86 ? 1012 HOH B O 1 HETATM 8741 O O . HOH O 6 . ? -33.010 122.013 16.753 1.00 25.86 ? 1013 HOH B O 1 HETATM 8742 O O . HOH O 6 . ? -22.980 139.581 4.111 1.00 22.16 ? 1014 HOH B O 1 HETATM 8743 O O . HOH O 6 . ? -9.923 117.830 1.000 1.00 12.58 ? 1015 HOH B O 1 HETATM 8744 O O . HOH O 6 . ? 13.106 117.911 -19.432 1.00 29.25 ? 1016 HOH B O 1 HETATM 8745 O O . HOH O 6 . ? -38.336 117.436 -3.328 1.00 43.15 ? 1017 HOH B O 1 HETATM 8746 O O . HOH O 6 . ? 20.920 117.359 -2.626 1.00 23.10 ? 1018 HOH B O 1 HETATM 8747 O O . HOH O 6 . ? -30.438 144.481 -5.999 1.00 28.23 ? 1019 HOH B O 1 HETATM 8748 O O . HOH O 6 . ? -18.552 102.511 -12.764 1.00 26.44 ? 1020 HOH B O 1 HETATM 8749 O O . HOH O 6 . ? -35.110 115.103 11.167 1.00 35.06 ? 1021 HOH B O 1 HETATM 8750 O O . HOH O 6 . ? -34.272 134.903 -13.684 1.00 39.64 ? 1022 HOH B O 1 HETATM 8751 O O . HOH O 6 . ? -9.597 134.211 23.697 1.00 44.86 ? 1023 HOH B O 1 HETATM 8752 O O . HOH O 6 . ? -36.484 128.650 -17.383 1.00 38.70 ? 1024 HOH B O 1 HETATM 8753 O O . HOH O 6 . ? 19.460 125.654 7.155 1.00 29.27 ? 1025 HOH B O 1 HETATM 8754 O O . HOH O 6 . ? -16.252 133.123 -9.630 1.00 38.95 ? 1026 HOH B O 1 HETATM 8755 O O . HOH O 6 . ? 5.181 109.560 -17.060 1.00 35.16 ? 1027 HOH B O 1 HETATM 8756 O O . HOH O 6 . ? -14.727 130.505 -4.412 1.00 20.77 ? 1028 HOH B O 1 HETATM 8757 O O . HOH O 6 . ? 10.770 104.611 -23.593 1.00 42.83 ? 1029 HOH B O 1 HETATM 8758 O O . HOH O 6 . ? -23.045 115.788 -22.887 1.00 33.56 ? 1030 HOH B O 1 HETATM 8759 O O . HOH O 6 . ? 8.929 120.158 18.914 1.00 28.26 ? 1031 HOH B O 1 HETATM 8760 O O . HOH O 6 . ? -46.415 125.447 -0.263 1.00 28.20 ? 1032 HOH B O 1 HETATM 8761 O O . HOH O 6 . ? -12.503 126.525 -10.505 1.00 21.33 ? 1033 HOH B O 1 HETATM 8762 O O . HOH O 6 . ? 15.887 119.710 -20.957 1.00 50.86 ? 1034 HOH B O 1 HETATM 8763 O O . HOH O 6 . ? -24.873 109.865 -18.868 1.00 22.24 ? 1035 HOH B O 1 HETATM 8764 O O . HOH O 6 . ? 7.531 108.055 -20.758 1.00 37.31 ? 1036 HOH B O 1 HETATM 8765 O O . HOH O 6 . ? -25.197 112.231 -21.173 1.00 41.43 ? 1037 HOH B O 1 HETATM 8766 O O . HOH O 6 . ? 11.007 131.571 -1.712 1.00 23.95 ? 1038 HOH B O 1 HETATM 8767 O O . HOH O 6 . ? 19.320 115.861 -6.095 1.00 39.46 ? 1039 HOH B O 1 HETATM 8768 O O . HOH O 6 . ? 5.043 120.768 -14.647 1.00 15.57 ? 1040 HOH B O 1 HETATM 8769 O O . HOH O 6 . ? 18.354 125.008 -15.270 1.00 25.57 ? 1041 HOH B O 1 HETATM 8770 O O . HOH O 6 . ? -25.341 115.859 -9.326 1.00 16.54 ? 1042 HOH B O 1 HETATM 8771 O O . HOH O 6 . ? -13.250 132.831 22.786 1.00 39.02 ? 1043 HOH B O 1 HETATM 8772 O O . HOH O 6 . ? -16.051 111.023 -12.335 1.00 14.77 ? 1044 HOH B O 1 HETATM 8773 O O . HOH O 6 . ? -4.664 119.091 17.726 1.00 25.73 ? 1045 HOH B O 1 HETATM 8774 O O . HOH O 6 . ? -23.932 126.205 21.696 1.00 40.20 ? 1046 HOH B O 1 HETATM 8775 O O . HOH O 6 . ? 12.722 109.872 -15.497 1.00 23.51 ? 1047 HOH B O 1 HETATM 8776 O O . HOH O 6 . ? 5.528 122.358 19.259 1.00 45.02 ? 1048 HOH B O 1 HETATM 8777 O O . HOH O 6 . ? -4.013 116.720 15.164 1.00 19.87 ? 1049 HOH B O 1 HETATM 8778 O O . HOH O 6 . ? 6.943 127.419 2.326 1.00 24.32 ? 1050 HOH B O 1 HETATM 8779 O O . HOH O 6 . ? -18.508 106.177 -7.507 1.00 14.65 ? 1051 HOH B O 1 HETATM 8780 O O . HOH O 6 . ? -34.423 120.349 -14.688 1.00 27.39 ? 1052 HOH B O 1 HETATM 8781 O O . HOH O 6 . ? -25.526 133.472 -16.958 1.00 22.69 ? 1053 HOH B O 1 HETATM 8782 O O . HOH O 6 . ? -17.994 130.407 -7.120 1.00 18.66 ? 1054 HOH B O 1 HETATM 8783 O O . HOH O 6 . ? -7.330 105.755 1.916 1.00 14.39 ? 1055 HOH B O 1 HETATM 8784 O O . HOH O 6 . ? 11.454 130.621 3.860 1.00 27.12 ? 1056 HOH B O 1 HETATM 8785 O O . HOH O 6 . ? -14.053 143.023 8.298 1.00 44.78 ? 1057 HOH B O 1 HETATM 8786 O O . HOH O 6 . ? -1.314 117.515 -4.383 1.00 17.04 ? 1058 HOH B O 1 HETATM 8787 O O . HOH O 6 . ? -3.242 108.529 11.586 1.00 31.97 ? 1059 HOH B O 1 HETATM 8788 O O . HOH O 6 . ? 10.036 101.503 0.710 1.00 34.35 ? 1060 HOH B O 1 HETATM 8789 O O . HOH O 6 . ? -23.346 142.044 -5.627 1.00 35.98 ? 1061 HOH B O 1 HETATM 8790 O O . HOH O 6 . ? -3.304 124.186 -15.830 1.00 21.81 ? 1062 HOH B O 1 HETATM 8791 O O . HOH O 6 . ? -2.318 118.319 16.755 1.00 37.76 ? 1063 HOH B O 1 HETATM 8792 O O . HOH O 6 . ? 7.846 117.282 -22.566 1.00 48.04 ? 1064 HOH B O 1 HETATM 8793 O O . HOH O 6 . ? 11.490 128.697 17.276 1.00 37.12 ? 1065 HOH B O 1 HETATM 8794 O O . HOH O 6 . ? -4.560 105.601 1.620 1.00 17.43 ? 1066 HOH B O 1 HETATM 8795 O O . HOH O 6 . ? -36.672 123.805 16.769 1.00 37.12 ? 1067 HOH B O 1 HETATM 8796 O O . HOH O 6 . ? 5.031 126.795 0.462 1.00 24.85 ? 1068 HOH B O 1 HETATM 8797 O O . HOH O 6 . ? -16.712 124.916 4.636 1.00 25.86 ? 1069 HOH B O 1 HETATM 8798 O O . HOH O 6 . ? 23.344 118.636 1.256 1.00 26.95 ? 1070 HOH B O 1 HETATM 8799 O O . HOH O 6 . ? 3.259 122.887 -15.188 1.00 25.08 ? 1071 HOH B O 1 HETATM 8800 O O . HOH O 6 . ? -2.113 129.755 12.796 1.00 33.38 ? 1072 HOH B O 1 HETATM 8801 O O . HOH O 6 . ? -38.149 131.678 -3.617 1.00 31.05 ? 1073 HOH B O 1 HETATM 8802 O O . HOH O 6 . ? -19.475 140.970 -4.610 1.00 28.94 ? 1074 HOH B O 1 HETATM 8803 O O . HOH O 6 . ? -23.166 126.032 -17.713 1.00 27.46 ? 1075 HOH B O 1 HETATM 8804 O O . HOH O 6 . ? -12.054 123.043 -17.363 1.00 25.59 ? 1076 HOH B O 1 HETATM 8805 O O . HOH O 6 . ? -6.655 134.759 7.151 1.00 37.55 ? 1077 HOH B O 1 HETATM 8806 O O . HOH O 6 . ? -38.166 117.036 -10.343 1.00 48.12 ? 1078 HOH B O 1 HETATM 8807 O O . HOH O 6 . ? 14.050 117.584 14.501 1.00 29.26 ? 1079 HOH B O 1 HETATM 8808 O O . HOH O 6 . ? 14.472 105.786 -2.085 1.00 32.24 ? 1080 HOH B O 1 HETATM 8809 O O . HOH O 6 . ? 16.319 106.946 -0.279 1.00 42.05 ? 1081 HOH B O 1 HETATM 8810 O O . HOH O 6 . ? -0.311 128.739 2.220 1.00 23.53 ? 1082 HOH B O 1 HETATM 8811 O O . HOH O 6 . ? 3.060 129.588 8.727 1.00 39.18 ? 1083 HOH B O 1 HETATM 8812 O O . HOH O 6 . ? -10.728 141.958 7.270 1.00 45.80 ? 1084 HOH B O 1 HETATM 8813 O O . HOH O 6 . ? 4.983 129.467 11.413 1.00 37.45 ? 1085 HOH B O 1 HETATM 8814 O O . HOH O 6 . ? 21.425 118.519 -8.733 1.00 40.79 ? 1086 HOH B O 1 HETATM 8815 O O . HOH O 6 . ? 6.246 107.691 9.346 1.00 20.35 ? 1087 HOH B O 1 HETATM 8816 O O . HOH O 6 . ? 3.009 110.710 13.365 1.00 26.74 ? 1088 HOH B O 1 HETATM 8817 O O . HOH O 6 . ? -5.867 115.735 -10.181 1.00 21.73 ? 1089 HOH B O 1 HETATM 8818 O O . HOH O 6 . ? -6.854 138.273 2.676 1.00 51.43 ? 1090 HOH B O 1 HETATM 8819 O O . HOH O 6 . ? 12.343 122.462 -19.352 1.00 34.05 ? 1091 HOH B O 1 HETATM 8820 O O . HOH O 6 . ? -10.031 111.201 -24.003 1.00 43.53 ? 1092 HOH B O 1 HETATM 8821 O O . HOH O 6 . ? -18.577 103.645 -8.048 1.00 32.87 ? 1093 HOH B O 1 HETATM 8822 O O . HOH O 6 . ? -15.621 107.998 -22.512 1.00 30.97 ? 1094 HOH B O 1 HETATM 8823 O O . HOH O 6 . ? -36.477 114.057 -14.003 1.00 30.73 ? 1095 HOH B O 1 HETATM 8824 O O . HOH O 6 . ? -38.966 139.093 -12.973 1.00 38.25 ? 1096 HOH B O 1 HETATM 8825 O O . HOH O 6 . ? 3.886 128.222 -15.907 1.00 42.10 ? 1097 HOH B O 1 HETATM 8826 O O . HOH O 6 . ? 23.484 114.148 -3.374 1.00 45.32 ? 1098 HOH B O 1 HETATM 8827 O O . HOH O 6 . ? -18.527 104.599 -3.060 1.00 30.14 ? 1099 HOH B O 1 HETATM 8828 O O . HOH O 6 . ? -15.536 127.415 18.509 1.00 26.10 ? 1100 HOH B O 1 HETATM 8829 O O . HOH O 6 . ? -3.592 131.217 14.308 1.00 33.11 ? 1101 HOH B O 1 HETATM 8830 O O . HOH O 6 . ? -18.414 135.580 -11.385 1.00 40.18 ? 1102 HOH B O 1 HETATM 8831 O O . HOH O 6 . ? -39.511 136.890 14.656 1.00 32.53 ? 1103 HOH B O 1 HETATM 8832 O O . HOH O 6 . ? -17.645 103.672 2.612 1.00 31.65 ? 1104 HOH B O 1 HETATM 8833 O O . HOH O 6 . ? -4.266 115.503 18.491 1.00 44.33 ? 1105 HOH B O 1 HETATM 8834 O O . HOH O 6 . ? 19.952 125.860 -6.675 1.00 39.31 ? 1106 HOH B O 1 HETATM 8835 O O . HOH O 6 . ? -12.242 129.145 -10.688 1.00 33.61 ? 1107 HOH B O 1 HETATM 8836 O O . HOH O 6 . ? -51.581 128.613 -0.312 1.00 41.11 ? 1108 HOH B O 1 HETATM 8837 O O . HOH O 6 . ? -3.755 118.356 -16.339 1.00 36.03 ? 1109 HOH B O 1 HETATM 8838 O O . HOH O 6 . ? 13.802 113.490 14.277 1.00 38.28 ? 1110 HOH B O 1 HETATM 8839 O O . HOH O 6 . ? -14.999 107.740 6.605 1.00 41.64 ? 1111 HOH B O 1 HETATM 8840 O O . HOH O 6 . ? -29.067 107.045 -13.951 1.00 36.62 ? 1112 HOH B O 1 HETATM 8841 O O . HOH O 6 . ? -29.045 114.605 -2.968 1.00 31.40 ? 1113 HOH B O 1 HETATM 8842 O O . HOH O 6 . ? -51.534 125.691 -9.211 1.00 40.26 ? 1114 HOH B O 1 HETATM 8843 O O . HOH O 6 . ? 5.027 132.815 -9.253 1.00 38.60 ? 1115 HOH B O 1 HETATM 8844 O O . HOH O 6 . ? -12.637 111.298 20.409 1.00 37.00 ? 1116 HOH B O 1 HETATM 8845 O O . HOH O 6 . ? -32.654 113.420 -6.459 1.00 40.30 ? 1117 HOH B O 1 HETATM 8846 O O . HOH O 6 . ? 14.860 111.436 -14.883 1.00 23.02 ? 1118 HOH B O 1 HETATM 8847 O O . HOH O 6 . ? 15.563 127.713 -16.976 1.00 31.26 ? 1119 HOH B O 1 HETATM 8848 O O . HOH O 6 . ? -26.264 107.397 -16.802 1.00 45.19 ? 1120 HOH B O 1 HETATM 8849 O O . HOH O 6 . ? 18.578 124.259 10.169 1.00 33.20 ? 1121 HOH B O 1 HETATM 8850 O O . HOH O 6 . ? -27.306 147.198 -6.667 1.00 51.17 ? 1122 HOH B O 1 HETATM 8851 O O . HOH O 6 . ? 11.508 131.291 -12.078 1.00 40.30 ? 1123 HOH B O 1 HETATM 8852 O O . HOH O 6 . ? -20.309 141.227 9.030 1.00 51.55 ? 1124 HOH B O 1 HETATM 8853 O O . HOH O 6 . ? -23.816 130.889 21.774 1.00 41.40 ? 1125 HOH B O 1 HETATM 8854 O O . HOH O 6 . ? -39.070 138.634 21.947 1.00 49.25 ? 1126 HOH B O 1 HETATM 8855 O O . HOH O 6 . ? -9.733 116.752 -20.985 1.00 38.98 ? 1127 HOH B O 1 HETATM 8856 O O . HOH O 6 . ? -6.752 105.704 9.934 1.00 37.81 ? 1128 HOH B O 1 HETATM 8857 O O . HOH O 6 . ? 1.715 99.646 -1.780 1.00 37.31 ? 1129 HOH B O 1 HETATM 8858 O O . HOH O 6 . ? 19.829 119.146 19.439 1.00 50.33 ? 1130 HOH B O 1 HETATM 8859 O O . HOH O 6 . ? -9.951 103.254 -9.074 1.00 28.06 ? 1131 HOH B O 1 HETATM 8860 O O . HOH O 6 . ? 19.323 121.034 19.068 1.00 42.28 ? 1132 HOH B O 1 HETATM 8861 O O . HOH O 6 . ? 21.723 117.274 -5.194 1.00 45.81 ? 1133 HOH B O 1 HETATM 8862 O O . HOH O 6 . ? -3.553 129.677 -10.554 1.00 37.07 ? 1134 HOH B O 1 HETATM 8863 O O . HOH O 6 . ? -27.097 105.549 -6.651 1.00 44.65 ? 1135 HOH B O 1 HETATM 8864 O O . HOH O 6 . ? -36.821 130.312 -1.934 1.00 31.75 ? 1136 HOH B O 1 HETATM 8865 O O . HOH O 6 . ? 8.875 131.238 -11.093 1.00 42.50 ? 1137 HOH B O 1 HETATM 8866 O O . HOH O 6 . ? 9.209 104.510 -21.373 1.00 40.03 ? 1138 HOH B O 1 HETATM 8867 O O . HOH O 6 . ? -27.625 104.934 2.315 1.00 37.47 ? 1139 HOH B O 1 HETATM 8868 O O . HOH O 6 . ? -27.883 115.313 -23.694 1.00 47.38 ? 1140 HOH B O 1 HETATM 8869 O O . HOH O 6 . ? -16.727 106.040 8.345 1.00 43.99 ? 1141 HOH B O 1 HETATM 8870 O O . HOH O 6 . ? -22.463 122.025 24.313 1.00 45.13 ? 1142 HOH B O 1 HETATM 8871 O O . HOH O 6 . ? 17.991 104.409 5.423 1.00 43.89 ? 1143 HOH B O 1 HETATM 8872 O O . HOH O 6 . ? -12.167 118.552 -23.461 1.00 39.02 ? 1144 HOH B O 1 HETATM 8873 O O . HOH O 6 . ? -5.870 104.660 5.562 1.00 43.28 ? 1145 HOH B O 1 HETATM 8874 O O . HOH O 6 . ? -26.399 143.269 7.195 1.00 39.28 ? 1146 HOH B O 1 HETATM 8875 O O . HOH O 6 . ? 4.035 104.353 -9.278 1.00 31.53 ? 1147 HOH B O 1 HETATM 8876 O O . HOH O 6 . ? -5.465 132.169 6.053 1.00 39.86 ? 1148 HOH B O 1 HETATM 8877 O O . HOH O 6 . ? -38.002 129.916 -5.752 1.00 27.08 ? 1149 HOH B O 1 HETATM 8878 O O . HOH O 6 . ? -14.874 141.974 0.702 1.00 42.92 ? 1150 HOH B O 1 HETATM 8879 O O . HOH O 6 . ? -30.203 134.640 -6.103 1.00 26.19 ? 1151 HOH B O 1 HETATM 8880 O O . HOH O 6 . ? 13.585 107.537 -16.204 1.00 41.14 ? 1152 HOH B O 1 HETATM 8881 O O . HOH O 6 . ? -3.727 103.157 0.917 1.00 20.24 ? 1153 HOH B O 1 HETATM 8882 O O . HOH O 6 . ? -34.685 126.398 -16.968 1.00 31.16 ? 1154 HOH B O 1 HETATM 8883 O O . HOH O 6 . ? -14.993 130.837 -6.880 1.00 30.87 ? 1155 HOH B O 1 HETATM 8884 O O . HOH O 6 . ? -0.151 104.481 -10.344 1.00 24.11 ? 1156 HOH B O 1 HETATM 8885 O O . HOH O 6 . ? -35.578 118.947 -20.167 1.00 40.96 ? 1157 HOH B O 1 HETATM 8886 O O . HOH O 6 . ? 7.244 126.660 13.267 1.00 22.73 ? 1158 HOH B O 1 HETATM 8887 O O . HOH O 6 . ? -22.595 119.890 -20.533 1.00 23.71 ? 1159 HOH B O 1 HETATM 8888 O O . HOH O 6 . ? -46.139 121.476 -10.650 1.00 49.68 ? 1160 HOH B O 1 HETATM 8889 O O . HOH O 6 . ? 4.456 119.761 17.446 1.00 47.51 ? 1161 HOH B O 1 HETATM 8890 O O . HOH O 6 . ? -15.073 121.401 -20.765 1.00 39.60 ? 1162 HOH B O 1 HETATM 8891 O O . HOH O 6 . ? -8.528 128.186 -13.956 1.00 46.44 ? 1163 HOH B O 1 HETATM 8892 O O . HOH O 6 . ? -42.820 120.295 -0.284 1.00 46.34 ? 1164 HOH B O 1 HETATM 8893 O O . HOH O 6 . ? -44.411 122.636 -1.296 1.00 42.40 ? 1165 HOH B O 1 HETATM 8894 O O . HOH O 6 . ? -33.075 114.414 18.914 1.00 41.57 ? 1166 HOH B O 1 HETATM 8895 O O . HOH O 6 . ? 19.205 128.023 -6.967 1.00 33.57 ? 1167 HOH B O 1 HETATM 8896 O O . HOH O 6 . ? -13.398 123.090 -19.266 1.00 41.70 ? 1168 HOH B O 1 HETATM 8897 O O . HOH O 6 . ? 9.078 102.982 3.051 1.00 40.92 ? 1169 HOH B O 1 HETATM 8898 O O . HOH O 6 . ? -1.468 128.248 -14.495 1.00 41.85 ? 1170 HOH B O 1 HETATM 8899 O O . HOH O 6 . ? 12.203 102.880 -12.290 1.00 19.00 ? 1171 HOH B O 1 HETATM 8900 O O . HOH O 6 . ? -3.323 110.612 15.948 1.00 37.71 ? 1172 HOH B O 1 HETATM 8901 O O . HOH O 6 . ? -0.937 109.678 12.554 1.00 27.62 ? 1173 HOH B O 1 HETATM 8902 O O . HOH O 6 . ? -4.394 106.002 4.220 1.00 28.06 ? 1174 HOH B O 1 HETATM 8903 O O . HOH O 6 . ? -16.358 137.282 13.184 1.00 40.21 ? 1175 HOH B O 1 HETATM 8904 O O . HOH O 6 . ? 17.985 112.420 -6.103 1.00 31.95 ? 1176 HOH B O 1 HETATM 8905 O O . HOH O 6 . ? -38.865 118.900 1.514 1.00 45.62 ? 1177 HOH B O 1 HETATM 8906 O O . HOH O 6 . ? 21.986 106.259 11.242 1.00 41.67 ? 1178 HOH B O 1 HETATM 8907 O O . HOH O 6 . ? -30.915 105.853 6.708 1.00 46.47 ? 1179 HOH B O 1 HETATM 8908 O O . HOH O 6 . ? -16.520 106.493 -3.689 1.00 30.63 ? 1180 HOH B O 1 HETATM 8909 O O . HOH O 6 . ? -4.895 114.981 -12.567 1.00 30.02 ? 1181 HOH B O 1 HETATM 8910 O O . HOH O 6 . ? 7.638 128.731 11.969 1.00 41.74 ? 1182 HOH B O 1 HETATM 8911 O O . HOH O 6 . ? 30.564 116.882 1.216 1.00 43.17 ? 1183 HOH B O 1 HETATM 8912 O O . HOH O 6 . ? -0.807 127.170 5.162 1.00 20.75 ? 1184 HOH B O 1 HETATM 8913 O O . HOH O 6 . ? -44.833 133.602 -18.712 1.00 43.88 ? 1185 HOH B O 1 HETATM 8914 O O . HOH O 6 . ? -32.915 103.814 7.920 1.00 43.42 ? 1186 HOH B O 1 HETATM 8915 O O . HOH O 6 . ? -27.148 109.624 10.232 1.00 26.82 ? 1187 HOH B O 1 HETATM 8916 O O . HOH O 6 . ? -41.121 139.209 -14.971 1.00 31.17 ? 1188 HOH B O 1 HETATM 8917 O O . HOH O 6 . ? 4.888 126.592 14.460 1.00 33.02 ? 1189 HOH B O 1 HETATM 8918 O O . HOH O 6 . ? 13.008 106.413 6.676 1.00 42.28 ? 1190 HOH B O 1 HETATM 8919 O O . HOH O 6 . ? 10.945 102.911 5.449 1.00 39.93 ? 1191 HOH B O 1 HETATM 8920 O O . HOH O 6 . ? -4.788 121.364 19.332 1.00 45.47 ? 1192 HOH B O 1 HETATM 8921 O O . HOH O 6 . ? -37.220 136.819 -15.404 1.00 33.19 ? 1193 HOH B O 1 HETATM 8922 O O . HOH O 6 . ? -25.190 146.077 -3.959 1.00 42.33 ? 1194 HOH B O 1 HETATM 8923 O O . HOH O 6 . ? -25.827 114.638 -25.035 1.00 34.44 ? 1195 HOH B O 1 HETATM 8924 O O . HOH O 6 . ? 6.889 119.012 17.780 1.00 38.09 ? 1196 HOH B O 1 HETATM 8925 O O . HOH O 6 . ? 7.542 104.424 -22.432 1.00 44.13 ? 1197 HOH B O 1 HETATM 8926 O O . HOH O 6 . ? -20.582 126.024 -16.824 1.00 34.34 ? 1198 HOH B O 1 HETATM 8927 O O . HOH O 6 . ? 22.557 117.862 -6.923 1.00 48.36 ? 1199 HOH B O 1 HETATM 8928 O O . HOH O 6 . ? 5.279 117.450 -23.755 1.00 50.98 ? 1200 HOH B O 1 HETATM 8929 O O . HOH O 6 . ? -1.145 129.389 4.582 1.00 41.52 ? 1201 HOH B O 1 HETATM 8930 O O . HOH O 6 . ? -36.824 121.943 -13.716 1.00 43.93 ? 1202 HOH B O 1 HETATM 8931 O O . HOH O 6 . ? -20.891 123.546 -20.040 1.00 37.80 ? 1203 HOH B O 1 HETATM 8932 O O . HOH O 6 . ? 0.720 100.228 3.425 1.00 47.69 ? 1204 HOH B O 1 HETATM 8933 O O . HOH O 6 . ? -21.896 125.963 22.876 1.00 40.50 ? 1205 HOH B O 1 HETATM 8934 O O . HOH O 6 . ? 12.969 117.145 19.146 1.00 50.72 ? 1206 HOH B O 1 HETATM 8935 O O . HOH O 6 . ? 6.274 115.567 12.186 1.00 19.15 ? 1207 HOH B O 1 HETATM 8936 O O . HOH O 6 . ? 7.787 121.126 21.369 1.00 46.56 ? 1208 HOH B O 1 HETATM 8937 O O . HOH O 6 . ? -27.605 144.774 -6.590 1.00 36.68 ? 1209 HOH B O 1 HETATM 8938 O O . HOH O 6 . ? -22.366 135.302 24.628 1.00 51.69 ? 1210 HOH B O 1 HETATM 8939 O O . HOH O 6 . ? 19.729 127.337 0.551 1.00 40.24 ? 1211 HOH B O 1 HETATM 8940 O O . HOH O 6 . ? -12.928 103.132 -8.879 1.00 33.49 ? 1212 HOH B O 1 HETATM 8941 O O . HOH O 6 . ? 26.229 119.119 1.940 1.00 45.02 ? 1213 HOH B O 1 HETATM 8942 O O . HOH O 6 . ? -5.422 99.096 0.718 1.00 37.12 ? 1214 HOH B O 1 HETATM 8943 O O . HOH O 6 . ? 7.057 116.504 16.359 1.00 33.85 ? 1215 HOH B O 1 HETATM 8944 O O . HOH O 6 . ? -8.066 103.200 1.319 1.00 23.07 ? 1216 HOH B O 1 HETATM 8945 O O . HOH O 6 . ? -28.930 117.330 -23.197 1.00 39.43 ? 1217 HOH B O 1 HETATM 8946 O O . HOH O 6 . ? 9.123 126.965 17.224 1.00 29.02 ? 1218 HOH B O 1 HETATM 8947 O O . HOH O 6 . ? -36.317 120.146 0.239 1.00 43.72 ? 1219 HOH B O 1 HETATM 8948 O O . HOH O 6 . ? 13.854 115.259 -20.265 1.00 44.18 ? 1220 HOH B O 1 HETATM 8949 O O . HOH O 6 . ? -29.878 107.322 -11.640 1.00 36.47 ? 1221 HOH B O 1 HETATM 8950 O O . HOH O 6 . ? -23.391 127.780 -19.852 1.00 30.07 ? 1222 HOH B O 1 HETATM 8951 O O . HOH O 6 . ? -2.294 126.400 -16.944 1.00 36.94 ? 1223 HOH B O 1 HETATM 8952 O O . HOH O 6 . ? -16.862 103.656 -8.051 1.00 35.95 ? 1224 HOH B O 1 HETATM 8953 O O . HOH O 6 . ? -18.833 141.136 10.434 1.00 44.38 ? 1225 HOH B O 1 HETATM 8954 O O . HOH O 6 . ? -41.589 121.225 -11.093 1.00 43.16 ? 1226 HOH B O 1 HETATM 8955 O O . HOH O 6 . ? 8.085 123.890 21.690 1.00 44.87 ? 1227 HOH B O 1 HETATM 8956 O O . HOH O 6 . ? 8.141 105.383 9.124 1.00 48.78 ? 1228 HOH B O 1 HETATM 8957 O O . HOH O 6 . ? 18.465 112.648 -12.432 1.00 36.12 ? 1229 HOH B O 1 HETATM 8958 O O . HOH O 6 . ? 0.444 104.586 4.946 1.00 33.34 ? 1230 HOH B O 1 HETATM 8959 O O . HOH O 6 . ? -10.343 121.354 -20.968 1.00 48.46 ? 1231 HOH B O 1 HETATM 8960 O O . HOH O 6 . ? -1.656 120.390 -18.498 1.00 57.50 ? 1232 HOH B O 1 HETATM 8961 O O . HOH O 6 . ? 4.541 115.194 16.300 1.00 33.32 ? 1233 HOH B O 1 HETATM 8962 O O . HOH O 6 . ? -27.316 108.078 -8.118 1.00 39.21 ? 1234 HOH B O 1 HETATM 8963 O O . HOH O 6 . ? -14.840 104.119 -7.631 1.00 27.01 ? 1235 HOH B O 1 HETATM 8964 O O . HOH O 6 . ? -16.646 135.344 -10.743 1.00 51.31 ? 1236 HOH B O 1 HETATM 8965 O O . HOH O 6 . ? 13.462 124.448 -20.946 1.00 45.44 ? 1237 HOH B O 1 HETATM 8966 O O . HOH O 6 . ? 0.591 131.912 -11.008 1.00 43.93 ? 1238 HOH B O 1 HETATM 8967 O O . HOH O 6 . ? 1.682 96.912 -3.629 1.00 30.28 ? 1239 HOH B O 1 HETATM 8968 O O . HOH O 6 . ? 20.576 108.575 -1.349 1.00 37.19 ? 1240 HOH B O 1 HETATM 8969 O O . HOH O 6 . ? 11.427 127.848 13.436 1.00 27.93 ? 1241 HOH B O 1 HETATM 8970 O O . HOH O 6 . ? -15.370 133.920 21.547 1.00 46.98 ? 1242 HOH B O 1 HETATM 8971 O O . HOH O 6 . ? 7.274 127.298 -19.528 1.00 36.19 ? 1243 HOH B O 1 HETATM 8972 O O . HOH O 6 . ? -23.404 140.232 7.056 1.00 45.86 ? 1244 HOH B O 1 HETATM 8973 O O . HOH O 6 . ? -9.739 126.107 -11.276 1.00 24.93 ? 1245 HOH B O 1 HETATM 8974 O O . HOH O 6 . ? 2.133 103.612 -7.774 1.00 36.11 ? 1246 HOH B O 1 HETATM 8975 O O . HOH O 6 . ? -22.018 131.350 -15.779 1.00 36.64 ? 1247 HOH B O 1 HETATM 8976 O O . HOH O 6 . ? -4.806 137.056 6.419 1.00 51.45 ? 1248 HOH B O 1 HETATM 8977 O O . HOH O 6 . ? 16.286 102.176 -11.882 1.00 45.67 ? 1249 HOH B O 1 HETATM 8978 O O . HOH O 6 . ? -1.642 130.504 1.491 1.00 41.23 ? 1250 HOH B O 1 HETATM 8979 O O . HOH O 6 . ? -8.260 136.296 12.806 1.00 47.82 ? 1251 HOH B O 1 HETATM 8980 O O . HOH O 6 . ? 30.813 112.110 0.612 1.00 41.89 ? 1252 HOH B O 1 HETATM 8981 O O . HOH O 6 . ? -28.066 134.096 -17.519 1.00 24.51 ? 1253 HOH B O 1 HETATM 8982 O O . HOH O 6 . ? -22.993 141.287 -8.694 1.00 46.07 ? 1254 HOH B O 1 HETATM 8983 O O . HOH O 6 . ? -0.923 106.834 9.171 1.00 38.85 ? 1255 HOH B O 1 HETATM 8984 O O . HOH O 6 . ? 7.098 113.125 13.304 1.00 33.43 ? 1256 HOH B O 1 HETATM 8985 O O . HOH O 6 . ? -8.135 121.050 -17.031 1.00 44.79 ? 1257 HOH B O 1 HETATM 8986 O O . HOH O 6 . ? -19.134 122.365 -21.987 1.00 33.01 ? 1258 HOH B O 1 HETATM 8987 O O . HOH O 6 . ? 16.009 125.913 1.289 1.00 27.46 ? 1259 HOH B O 1 HETATM 8988 O O . HOH O 6 . ? -40.205 117.385 -3.642 1.00 49.41 ? 1260 HOH B O 1 HETATM 8989 O O . HOH O 6 . ? -16.619 127.181 22.217 1.00 41.58 ? 1261 HOH B O 1 HETATM 8990 O O . HOH O 6 . ? -7.713 105.557 4.501 1.00 35.50 ? 1262 HOH B O 1 HETATM 8991 O O . HOH O 6 . ? -10.096 102.235 2.450 1.00 47.52 ? 1263 HOH B O 1 HETATM 8992 O O . HOH O 6 . ? 0.300 128.040 17.665 1.00 46.65 ? 1264 HOH B O 1 HETATM 8993 O O . HOH O 6 . ? -23.395 134.591 -18.058 1.00 33.49 ? 1265 HOH B O 1 HETATM 8994 O O . HOH O 6 . ? 29.352 113.428 6.839 1.00 45.48 ? 1266 HOH B O 1 HETATM 8995 O O . HOH O 6 . ? 0.159 129.594 16.174 1.00 41.06 ? 1267 HOH B O 1 HETATM 8996 O O . HOH O 6 . ? -23.987 143.189 6.886 1.00 44.46 ? 1268 HOH B O 1 HETATM 8997 O O . HOH O 6 . ? -19.439 126.142 -19.946 1.00 43.28 ? 1269 HOH B O 1 HETATM 8998 O O . HOH O 6 . ? -4.332 120.751 -17.484 1.00 61.61 ? 1270 HOH B O 1 HETATM 8999 O O . HOH O 6 . ? -2.601 130.030 -13.715 1.00 49.78 ? 1271 HOH B O 1 HETATM 9000 O O . HOH O 6 . ? -41.621 123.993 -13.823 1.00 45.97 ? 1272 HOH B O 1 HETATM 9001 O O . HOH O 6 . ? 14.311 102.729 -14.122 1.00 30.17 ? 1273 HOH B O 1 HETATM 9002 O O . HOH O 6 . ? 4.973 119.932 -20.510 1.00 32.70 ? 1274 HOH B O 1 HETATM 9003 O O . HOH O 6 . ? 22.055 122.880 2.854 1.00 30.39 ? 1275 HOH B O 1 HETATM 9004 O O . HOH O 6 . ? -9.194 125.795 -13.893 1.00 34.30 ? 1276 HOH B O 1 HETATM 9005 O O . HOH O 6 . ? -39.223 117.084 -1.334 1.00 52.50 ? 1277 HOH B O 1 HETATM 9006 O O . HOH O 6 . ? -43.261 127.902 -16.106 1.00 39.35 ? 1278 HOH B O 1 HETATM 9007 O O . HOH O 6 . ? 17.229 108.481 -11.801 1.00 35.61 ? 1279 HOH B O 1 HETATM 9008 O O . HOH O 6 . ? 12.452 100.336 0.880 1.00 41.92 ? 1280 HOH B O 1 HETATM 9009 O O . HOH O 6 . ? -5.488 124.511 -17.339 1.00 40.55 ? 1281 HOH B O 1 HETATM 9010 O O . HOH O 6 . ? -4.641 132.517 3.413 1.00 41.22 ? 1282 HOH B O 1 HETATM 9011 O O . HOH O 6 . ? -36.855 118.436 -17.907 1.00 44.44 ? 1283 HOH B O 1 HETATM 9012 O O . HOH O 6 . ? 22.712 124.896 -6.128 1.00 41.47 ? 1284 HOH B O 1 HETATM 9013 O O . HOH O 6 . ? 18.520 126.156 1.729 1.00 36.07 ? 1285 HOH B O 1 HETATM 9014 O O . HOH O 6 . ? -10.167 136.410 -11.051 1.00 47.51 ? 1286 HOH B O 1 HETATM 9015 O O . HOH O 6 . ? -10.901 125.219 -16.751 1.00 39.45 ? 1287 HOH B O 1 HETATM 9016 O O . HOH O 6 . ? 10.289 118.633 23.145 1.00 47.37 ? 1288 HOH B O 1 HETATM 9017 O O . HOH O 6 . ? 20.999 125.065 1.922 1.00 43.80 ? 1289 HOH B O 1 HETATM 9018 O O . HOH O 6 . ? 10.236 118.009 19.793 1.00 43.09 ? 1290 HOH B O 1 HETATM 9019 O O . HOH O 6 . ? -14.518 118.981 -23.568 1.00 40.07 ? 1291 HOH B O 1 HETATM 9020 O O . HOH O 6 . ? -43.899 126.725 -11.916 1.00 33.83 ? 1292 HOH B O 1 HETATM 9021 O O . HOH O 6 . ? 3.319 133.081 -7.131 1.00 34.55 ? 1293 HOH B O 1 HETATM 9022 O O . HOH O 6 . ? 3.866 106.957 10.013 1.00 38.55 ? 1294 HOH B O 1 HETATM 9023 O O . HOH O 6 . ? 28.147 118.642 5.646 1.00 41.59 ? 1295 HOH B O 1 HETATM 9024 O O . HOH O 6 . ? 10.251 115.692 13.598 1.00 24.75 ? 1296 HOH B O 1 HETATM 9025 O O . HOH O 6 . ? 5.156 109.425 12.729 1.00 43.45 ? 1297 HOH B O 1 HETATM 9026 O O . HOH O 6 . ? 20.731 107.935 1.379 1.00 32.18 ? 1298 HOH B O 1 HETATM 9027 O O . HOH O 6 . ? 30.026 114.059 4.673 1.00 55.22 ? 1299 HOH B O 1 HETATM 9028 O O . HOH O 6 . ? -31.407 128.647 25.015 1.00 50.38 ? 1300 HOH B O 1 HETATM 9029 O O . HOH O 6 . ? 4.473 129.371 14.519 1.00 42.48 ? 1301 HOH B O 1 HETATM 9030 O O . HOH O 6 . ? -0.174 110.333 16.580 1.00 58.55 ? 1302 HOH B O 1 HETATM 9031 O O . HOH O 6 . ? 1.723 108.216 9.323 1.00 21.58 ? 1303 HOH B O 1 HETATM 9032 O O . HOH O 6 . ? 21.551 121.725 -12.895 1.00 49.99 ? 1304 HOH B O 1 HETATM 9033 O O . HOH O 6 . ? 3.657 129.257 4.411 1.00 25.72 ? 1305 HOH B O 1 HETATM 9034 O O . HOH O 6 . ? -42.477 149.570 -0.451 1.00 49.88 ? 1306 HOH B O 1 HETATM 9035 O O . HOH O 6 . ? 16.071 110.514 -10.362 1.00 25.12 ? 1307 HOH B O 1 HETATM 9036 O O . HOH O 6 . ? 17.184 126.945 2.939 1.00 35.06 ? 1308 HOH B O 1 HETATM 9037 O O . HOH O 6 . ? 23.110 122.760 9.698 1.00 37.27 ? 1309 HOH B O 1 HETATM 9038 O O . HOH O 6 . ? -21.296 133.227 -17.415 1.00 44.84 ? 1310 HOH B O 1 HETATM 9039 O O . HOH O 6 . ? 2.334 129.376 16.429 1.00 46.86 ? 1311 HOH B O 1 HETATM 9040 O O . HOH O 6 . ? -8.704 110.235 -22.397 1.00 45.29 ? 1312 HOH B O 1 HETATM 9041 O O . HOH O 6 . ? 0.391 131.401 12.321 1.00 38.53 ? 1313 HOH B O 1 HETATM 9042 O O . HOH O 6 . ? 31.462 114.023 0.431 1.00 41.95 ? 1314 HOH B O 1 HETATM 9043 O O . HOH O 6 . ? -43.960 124.275 -12.278 1.00 37.90 ? 1315 HOH B O 1 HETATM 9044 O O . HOH O 6 . ? 17.452 110.859 -8.246 1.00 31.01 ? 1316 HOH B O 1 HETATM 9045 O O . HOH O 6 . ? 1.524 109.963 15.709 1.00 41.80 ? 1317 HOH B O 1 HETATM 9046 O O . HOH O 6 . ? -18.924 119.665 -22.141 1.00 32.20 ? 1318 HOH B O 1 HETATM 9047 O O . HOH O 6 . ? 23.048 120.479 -10.543 1.00 47.76 ? 1319 HOH B O 1 HETATM 9048 O O . HOH O 6 . ? 8.967 120.168 23.509 1.00 42.51 ? 1320 HOH B O 1 HETATM 9049 O O . HOH O 6 . ? 30.832 116.139 3.305 1.00 42.64 ? 1321 HOH B O 1 HETATM 9050 O O . HOH O 6 . ? -32.357 123.537 25.704 1.00 48.10 ? 1322 HOH B O 1 HETATM 9051 O O . HOH O 6 . ? 9.078 115.389 17.736 1.00 53.65 ? 1323 HOH B O 1 HETATM 9052 O O . HOH O 6 . ? -31.706 125.167 26.121 1.00 57.18 ? 1324 HOH B O 1 HETATM 9053 O O . HOH O 6 . ? 3.256 98.349 6.364 1.00 47.73 ? 1325 HOH B O 1 HETATM 9054 O O . HOH O 6 . ? 3.082 104.825 12.171 1.00 50.12 ? 1326 HOH B O 1 HETATM 9055 O O . HOH O 6 . ? 3.215 96.046 6.661 1.00 46.29 ? 1327 HOH B O 1 HETATM 9056 O O . HOH P 6 . ? -45.960 145.748 3.394 1.00 46.43 ? 1401 HOH D O 1 HETATM 9057 O O . HOH P 6 . ? -43.850 138.777 13.951 1.00 40.55 ? 1402 HOH D O 1 HETATM 9058 O O . HOH P 6 . ? -41.871 132.947 9.948 1.00 28.58 ? 1403 HOH D O 1 HETATM 9059 O O . HOH P 6 . ? -50.253 139.615 11.830 1.00 42.69 ? 1404 HOH D O 1 HETATM 9060 O O . HOH P 6 . ? -52.158 138.184 14.291 1.00 38.83 ? 1405 HOH D O 1 HETATM 9061 O O . HOH P 6 . ? -40.252 129.133 11.893 1.00 28.86 ? 1406 HOH D O 1 HETATM 9062 O O . HOH P 6 . ? -40.525 139.760 5.984 1.00 29.72 ? 1407 HOH D O 1 HETATM 9063 O O . HOH P 6 . ? -43.142 147.116 -4.342 1.00 30.26 ? 1408 HOH D O 1 HETATM 9064 O O . HOH P 6 . ? -49.013 139.118 -0.068 1.00 30.28 ? 1409 HOH D O 1 HETATM 9065 O O . HOH P 6 . ? -42.884 125.356 4.450 1.00 34.38 ? 1410 HOH D O 1 HETATM 9066 O O . HOH P 6 . ? -46.503 144.189 13.735 1.00 30.38 ? 1411 HOH D O 1 HETATM 9067 O O . HOH P 6 . ? -43.263 146.955 6.319 1.00 50.92 ? 1412 HOH D O 1 HETATM 9068 O O . HOH P 6 . ? -40.060 129.567 1.059 1.00 28.87 ? 1413 HOH D O 1 HETATM 9069 O O . HOH P 6 . ? -48.886 140.950 6.215 1.00 46.79 ? 1414 HOH D O 1 HETATM 9070 O O . HOH P 6 . ? -48.363 136.906 1.365 1.00 28.52 ? 1415 HOH D O 1 HETATM 9071 O O . HOH P 6 . ? -47.866 139.838 -7.501 1.00 27.57 ? 1416 HOH D O 1 HETATM 9072 O O . HOH P 6 . ? -48.222 132.832 12.361 1.00 37.24 ? 1417 HOH D O 1 HETATM 9073 O O . HOH P 6 . ? -46.498 144.585 6.988 1.00 47.69 ? 1418 HOH D O 1 HETATM 9074 O O . HOH P 6 . ? -45.868 124.142 2.053 1.00 53.52 ? 1419 HOH D O 1 HETATM 9075 O O . HOH P 6 . ? -47.288 123.125 3.819 1.00 49.51 ? 1420 HOH D O 1 HETATM 9076 O O . HOH P 6 . ? -41.603 137.514 16.000 1.00 54.23 ? 1421 HOH D O 1 HETATM 9077 O O . HOH P 6 . ? -48.106 143.587 5.221 1.00 43.56 ? 1422 HOH D O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLY 1 53 ? ? ? A . n A 1 2 SER 2 54 ? ? ? A . n A 1 3 ALA 3 55 ? ? ? A . n A 1 4 MET 4 56 ? ? ? A . n A 1 5 GLY 5 57 ? ? ? A . n A 1 6 SER 6 58 ? ? ? A . n A 1 7 SER 7 59 59 SER SER A . n A 1 8 THR 8 60 60 THR THR A . n A 1 9 SER 9 61 61 SER SER A . n A 1 10 THR 10 62 62 THR THR A . n A 1 11 SER 11 63 63 SER SER A . n A 1 12 ARG 12 64 64 ARG ARG A . n A 1 13 ALA 13 65 65 ALA ALA A . n A 1 14 THR 14 66 66 THR THR A . n A 1 15 TYR 15 67 67 TYR TYR A . n A 1 16 MET 16 68 68 MET MET A . n A 1 17 ASP 17 69 69 ASP ASP A . n A 1 18 ARG 18 70 70 ARG ARG A . n A 1 19 PHE 19 71 71 PHE PHE A . n A 1 20 ASN 20 72 72 ASN ASN A . n A 1 21 ILE 21 73 73 ILE ILE A . n A 1 22 PRO 22 74 74 PRO PRO A . n A 1 23 LYS 23 75 75 LYS LYS A . n A 1 24 ASN 24 76 76 ASN ASN A . n A 1 25 HIS 25 77 77 HIS HIS A . n A 1 26 VAL 26 78 78 VAL VAL A . n A 1 27 ASP 27 79 79 ASP ASP A . n A 1 28 LEU 28 80 80 LEU LEU A . n A 1 29 ILE 29 81 81 ILE ILE A . n A 1 30 TRP 30 82 82 TRP TRP A . n A 1 31 ASP 31 83 83 ASP ASP A . n A 1 32 LYS 32 84 84 LYS LYS A . n A 1 33 ASP 33 85 85 ASP ASP A . n A 1 34 GLY 34 86 86 GLY GLY A . n A 1 35 THR 35 87 87 THR THR A . n A 1 36 LYS 36 88 88 LYS LYS A . n A 1 37 SER 37 89 89 SER SER A . n A 1 38 HIS 38 90 90 HIS HIS A . n A 1 39 THR 39 91 91 THR THR A . n A 1 40 ARG 40 92 92 ARG ARG A . n A 1 41 GLY 41 93 93 GLY GLY A . n A 1 42 ASN 42 94 94 ASN ASN A . n A 1 43 THR 43 95 95 THR THR A . n A 1 44 THR 44 96 96 THR THR A . n A 1 45 TYR 45 97 97 TYR TYR A . n A 1 46 ARG 46 98 98 ARG ARG A . n A 1 47 TRP 47 99 99 TRP TRP A . n A 1 48 THR 48 100 100 THR THR A . n A 1 49 GLU 49 101 101 GLU GLU A . n A 1 50 ARG 50 102 102 ARG ARG A . n A 1 51 LYS 51 103 103 LYS LYS A . n A 1 52 SER 52 104 104 SER SER A . n A 1 53 ASN 53 105 105 ASN ASN A . n A 1 54 VAL 54 106 106 VAL VAL A . n A 1 55 GLY 55 107 107 GLY GLY A . n A 1 56 VAL 56 108 108 VAL VAL A . n A 1 57 TYR 57 109 109 TYR TYR A . n A 1 58 VAL 58 110 110 VAL VAL A . n A 1 59 GLY 59 111 111 GLY GLY A . n A 1 60 TYR 60 112 112 TYR TYR A . n A 1 61 SER 61 113 113 SER SER A . n A 1 62 GLU 62 114 114 GLU GLU A . n A 1 63 MET 63 115 115 MET MET A . n A 1 64 TYR 64 116 116 TYR TYR A . n A 1 65 ASP 65 117 117 ASP ASP A . n A 1 66 SER 66 118 118 SER SER A . n A 1 67 SER 67 119 119 SER SER A . n A 1 68 ALA 68 120 120 ALA ALA A . n A 1 69 GLN 69 121 121 GLN GLN A . n A 1 70 ALA 70 122 122 ALA ALA A . n A 1 71 TYR 71 123 123 TYR TYR A . n A 1 72 CYS 72 124 124 CYS CYS A . n A 1 73 GLN 73 125 125 GLN GLN A . n A 1 74 SER 74 126 126 SER SER A . n A 1 75 SER 75 127 127 SER SER A . n A 1 76 SER 76 128 128 SER SER A . n A 1 77 ALA 77 129 129 ALA ALA A . n A 1 78 LYS 78 130 130 LYS LYS A . n A 1 79 ILE 79 131 131 ILE ILE A . n A 1 80 ASP 80 132 132 ASP ASP A . n A 1 81 THR 81 133 133 THR THR A . n A 1 82 LYS 82 134 134 LYS LYS A . n A 1 83 THR 83 135 135 THR THR A . n A 1 84 THR 84 136 136 THR THR A . n A 1 85 VAL 85 137 137 VAL VAL A . n A 1 86 GLY 86 138 138 GLY GLY A . n A 1 87 ALA 87 139 139 ALA ALA A . n A 1 88 PRO 88 140 140 PRO PRO A . n A 1 89 TYR 89 141 141 TYR TYR A . n A 1 90 MET 90 142 142 MET MET A . n A 1 91 ALA 91 143 143 ALA ALA A . n A 1 92 ALA 92 144 144 ALA ALA A . n A 1 93 GLY 93 145 145 GLY GLY A . n A 1 94 ALA 94 146 146 ALA ALA A . n A 1 95 CYS 95 147 147 CYS CYS A . n A 1 96 PRO 96 148 148 PRO PRO A . n A 1 97 ASN 97 149 149 ASN ASN A . n A 1 98 TYR 98 150 150 TYR TYR A . n A 1 99 GLY 99 151 151 GLY GLY A . n A 1 100 LYS 100 152 152 LYS LYS A . n A 1 101 VAL 101 153 153 VAL VAL A . n A 1 102 ILE 102 154 154 ILE ILE A . n A 1 103 ALA 103 155 155 ALA ALA A . n A 1 104 PHE 104 156 156 PHE PHE A . n A 1 105 THR 105 157 157 THR THR A . n A 1 106 LYS 106 158 158 LYS LYS A . n A 1 107 ARG 107 159 159 ARG ARG A . n A 1 108 ASP 108 160 160 ASP ASP A . n A 1 109 GLY 109 161 161 GLY GLY A . n A 1 110 SER 110 162 162 SER SER A . n A 1 111 ARG 111 163 163 ARG ARG A . n A 1 112 SER 112 164 164 SER SER A . n A 1 113 ASP 113 165 165 ASP ASP A . n A 1 114 MET 114 166 166 MET MET A . n A 1 115 THR 115 167 167 THR THR A . n A 1 116 ARG 116 168 168 ARG ARG A . n A 1 117 TRP 117 169 169 TRP TRP A . n A 1 118 LYS 118 170 170 LYS LYS A . n A 1 119 ASN 119 171 171 ASN ASN A . n A 1 120 GLU 120 172 172 GLU GLU A . n A 1 121 ILE 121 173 173 ILE ILE A . n A 1 122 HIS 122 174 174 HIS HIS A . n A 1 123 ALA 123 175 175 ALA ALA A . n A 1 124 ASN 124 176 176 ASN ASN A . n A 1 125 VAL 125 177 177 VAL VAL A . n A 1 126 MET 126 178 178 MET MET A . n A 1 127 PRO 127 179 179 PRO PRO A . n A 1 128 HIS 128 180 180 HIS HIS A . n A 1 129 SER 129 181 181 SER SER A . n A 1 130 THR 130 182 182 THR THR A . n A 1 131 THR 131 183 183 THR THR A . n A 1 132 SER 132 184 184 SER SER A . n A 1 133 CYS 133 185 185 CYS CYS A . n A 1 134 ALA 134 186 186 ALA ALA A . n A 1 135 SER 135 187 187 SER SER A . n A 1 136 ARG 136 188 188 ARG ARG A . n A 1 137 ALA 137 189 189 ALA ALA A . n A 1 138 ASP 138 190 190 ASP ASP A . n A 1 139 PRO 139 191 191 PRO PRO A . n A 1 140 GLY 140 192 192 GLY GLY A . n A 1 141 ALA 141 193 193 ALA ALA A . n A 1 142 ALA 142 194 194 ALA ALA A . n A 1 143 GLU 143 195 195 GLU GLU A . n A 1 144 VAL 144 196 196 VAL VAL A . n A 1 145 ALA 145 197 197 ALA ALA A . n A 1 146 LYS 146 198 198 LYS LYS A . n A 1 147 SER 147 199 199 SER SER A . n A 1 148 ILE 148 200 200 ILE ILE A . n A 1 149 GLU 149 201 201 GLU GLU A . n A 1 150 GLY 150 202 202 GLY GLY A . n A 1 151 PHE 151 203 203 PHE PHE A . n A 1 152 ALA 152 204 204 ALA ALA A . n A 1 153 MET 153 205 205 MET MET A . n A 1 154 TYR 154 206 206 TYR TYR A . n A 1 155 ALA 155 207 207 ALA ALA A . n A 1 156 GLY 156 208 208 GLY GLY A . n A 1 157 TYR 157 209 209 TYR TYR A . n A 1 158 LEU 158 210 210 LEU LEU A . n A 1 159 THR 159 211 211 THR THR A . n A 1 160 HIS 160 212 212 HIS HIS A . n A 1 161 CYS 161 213 213 CYS CYS A . n A 1 162 PRO 162 214 214 PRO PRO A . n A 1 163 TYR 163 215 215 TYR TYR A . n A 1 164 ASN 164 216 216 ASN ASN A . n A 1 165 VAL 165 217 217 VAL VAL A . n A 1 166 ASN 166 218 218 ASN ASN A . n A 1 167 VAL 167 219 219 VAL VAL A . n A 1 168 TYR 168 220 220 TYR TYR A . n A 1 169 ARG 169 221 221 ARG ARG A . n A 1 170 GLN 170 222 222 GLN GLN A . n A 1 171 ASP 171 223 223 ASP ASP A . n A 1 172 MET 172 224 224 MET MET A . n A 1 173 VAL 173 225 225 VAL VAL A . n A 1 174 THR 174 226 226 THR THR A . n A 1 175 ASP 175 227 227 ASP ASP A . n A 1 176 LYS 176 228 228 LYS LYS A . n A 1 177 GLU 177 229 229 GLU GLU A . n A 1 178 PHE 178 230 230 PHE PHE A . n A 1 179 ASP 179 231 231 ASP ASP A . n A 1 180 SER 180 232 232 SER SER A . n A 1 181 THR 181 233 233 THR THR A . n A 1 182 VAL 182 234 234 VAL VAL A . n A 1 183 CYS 183 235 235 CYS CYS A . n A 1 184 ASN 184 236 236 ASN ASN A . n A 1 185 PHE 185 237 237 PHE PHE A . n A 1 186 VAL 186 238 238 VAL VAL A . n A 1 187 THR 187 239 239 THR THR A . n A 1 188 GLU 188 240 240 GLU GLU A . n A 1 189 SER 189 241 241 SER SER A . n A 1 190 ASN 190 242 242 ASN ASN A . n A 1 191 PRO 191 243 243 PRO PRO A . n A 1 192 LEU 192 244 244 LEU LEU A . n A 1 193 ARG 193 245 245 ARG ARG A . n A 1 194 PHE 194 246 246 PHE PHE A . n A 1 195 LEU 195 247 247 LEU LEU A . n A 1 196 ASP 196 248 248 ASP ASP A . n A 1 197 THR 197 249 249 THR THR A . n A 1 198 THR 198 250 250 THR THR A . n A 1 199 GLN 199 251 251 GLN GLN A . n A 1 200 ARG 200 252 252 ARG ARG A . n A 1 201 GLN 201 253 253 GLN GLN A . n A 1 202 SER 202 254 254 SER SER A . n A 1 203 THR 203 255 255 THR THR A . n A 1 204 GLN 204 256 256 GLN GLN A . n A 1 205 PRO 205 257 257 PRO PRO A . n A 1 206 TYR 206 258 258 TYR TYR A . n A 1 207 THR 207 259 259 THR THR A . n A 1 208 GLU 208 260 260 GLU GLU A . n A 1 209 TYR 209 261 261 TYR TYR A . n A 1 210 ALA 210 262 262 ALA ALA A . n A 1 211 PHE 211 263 263 PHE PHE A . n A 1 212 HIS 212 264 264 HIS HIS A . n A 1 213 GLY 213 265 265 GLY GLY A . n A 1 214 LYS 214 266 266 LYS LYS A . n A 1 215 GLY 215 267 267 GLY GLY A . n A 1 216 GLY 216 268 268 GLY GLY A . n A 1 217 HIS 217 269 269 HIS HIS A . n A 1 218 LYS 218 270 270 LYS LYS A . n A 1 219 GLY 219 271 271 GLY GLY A . n A 1 220 TYR 220 272 272 TYR TYR A . n A 1 221 ASP 221 273 273 ASP ASP A . n A 1 222 TYR 222 274 274 TYR TYR A . n A 1 223 LYS 223 275 275 LYS LYS A . n A 1 224 GLY 224 276 276 GLY GLY A . n A 1 225 GLN 225 277 277 GLN GLN A . n A 1 226 THR 226 278 278 THR THR A . n A 1 227 SER 227 279 279 SER SER A . n A 1 228 HIS 228 280 280 HIS HIS A . n A 1 229 VAL 229 281 281 VAL VAL A . n A 1 230 GLY 230 282 282 GLY GLY A . n A 1 231 CYS 231 283 283 CYS CYS A . n A 1 232 PRO 232 284 284 PRO PRO A . n A 1 233 PRO 233 285 285 PRO PRO A . n A 1 234 TYR 234 286 286 TYR TYR A . n A 1 235 ASN 235 287 287 ASN ASN A . n A 1 236 PRO 236 288 288 PRO PRO A . n A 1 237 PRO 237 289 289 PRO PRO A . n A 1 238 HIS 238 290 290 HIS HIS A . n A 1 239 VAL 239 291 291 VAL VAL A . n A 1 240 THR 240 292 292 THR THR A . n A 1 241 LYS 241 293 293 LYS LYS A . n A 1 242 GLY 242 294 294 GLY GLY A . n A 1 243 MET 243 295 295 MET MET A . n A 1 244 LYS 244 296 296 LYS LYS A . n A 1 245 ASP 245 297 297 ASP ASP A . n A 1 246 SER 246 298 298 SER SER A . n A 1 247 SER 247 299 299 SER SER A . n A 1 248 TRP 248 300 300 TRP TRP A . n A 1 249 ILE 249 301 301 ILE ILE A . n A 1 250 THR 250 302 302 THR THR A . n A 1 251 GLY 251 303 303 GLY GLY A . n A 1 252 PRO 252 304 304 PRO PRO A . n A 1 253 PHE 253 305 305 PHE PHE A . n A 1 254 GLU 254 306 306 GLU GLU A . n A 1 255 CYS 255 307 307 CYS CYS A . n A 1 256 SER 256 308 308 SER SER A . n A 1 257 ILE 257 309 309 ILE ILE A . n A 1 258 LEU 258 310 310 LEU LEU A . n A 1 259 SER 259 311 311 SER SER A . n A 1 260 ARG 260 312 312 ARG ARG A . n A 1 261 CYS 261 313 313 CYS CYS A . n A 1 262 THR 262 314 314 THR THR A . n A 1 263 THR 263 315 315 THR THR A . n A 1 264 HIS 264 316 316 HIS HIS A . n A 1 265 CYS 265 317 317 CYS CYS A . n A 1 266 TRP 266 318 318 TRP TRP A . n A 1 267 PRO 267 319 319 PRO PRO A . n A 1 268 TYR 268 320 320 TYR TYR A . n A 1 269 LYS 269 321 321 LYS LYS A . n A 1 270 SER 270 322 322 SER SER A . n A 1 271 GLY 271 323 323 GLY GLY A . n A 1 272 GLY 272 324 324 GLY GLY A . n A 1 273 ASN 273 325 325 ASN ASN A . n A 1 274 CYS 274 326 326 CYS CYS A . n A 1 275 PHE 275 327 327 PHE PHE A . n A 1 276 ARG 276 328 328 ARG ARG A . n A 1 277 SER 277 329 329 SER SER A . n A 1 278 LEU 278 330 330 LEU LEU A . n A 1 279 PRO 279 331 331 PRO PRO A . n A 1 280 ALA 280 332 332 ALA ALA A . n A 1 281 MET 281 333 333 MET MET A . n A 1 282 PHE 282 334 334 PHE PHE A . n A 1 283 ASP 283 335 335 ASP ASP A . n A 1 284 MET 284 336 336 MET MET A . n A 1 285 SER 285 337 337 SER SER A . n A 1 286 THR 286 338 338 THR THR A . n A 1 287 GLY 287 339 339 GLY GLY A . n A 1 288 GLU 288 340 340 GLU GLU A . n A 1 289 CYS 289 341 341 CYS CYS A . n A 1 290 ARG 290 342 342 ARG ARG A . n A 1 291 LEU 291 343 343 LEU LEU A . n A 1 292 LEU 292 344 344 LEU LEU A . n A 1 293 GLY 293 345 345 GLY GLY A . n A 1 294 TYR 294 346 346 TYR TYR A . n A 1 295 HIS 295 347 347 HIS HIS A . n A 1 296 THR 296 348 348 THR THR A . n A 1 297 GLN 297 349 349 GLN GLN A . n A 1 298 ASP 298 350 350 ASP ASP A . n A 1 299 PHE 299 351 351 PHE PHE A . n A 1 300 ARG 300 352 352 ARG ARG A . n A 1 301 SER 301 353 353 SER SER A . n A 1 302 SER 302 354 354 SER SER A . n A 1 303 THR 303 355 355 THR THR A . n A 1 304 CYS 304 356 356 CYS CYS A . n A 1 305 ALA 305 357 357 ALA ALA A . n A 1 306 GLU 306 358 358 GLU GLU A . n A 1 307 LEU 307 359 359 LEU LEU A . n A 1 308 THR 308 360 360 THR THR A . n A 1 309 THR 309 361 361 THR THR A . n A 1 310 ASP 310 362 362 ASP ASP A . n A 1 311 ASP 311 363 363 ASP ASP A . n A 1 312 THR 312 364 364 THR THR A . n A 1 313 ASN 313 365 365 ASN ASN A . n A 1 314 ALA 314 366 366 ALA ALA A . n A 1 315 PHE 315 367 367 PHE PHE A . n A 1 316 TYR 316 368 368 TYR TYR A . n A 1 317 CYS 317 369 369 CYS CYS A . n A 1 318 VAL 318 370 370 VAL VAL A . n A 1 319 ARG 319 371 371 ARG ARG A . n A 1 320 PRO 320 372 372 PRO PRO A . n A 1 321 MET 321 373 373 MET MET A . n A 1 322 LYS 322 374 374 LYS LYS A . n A 1 323 THR 323 375 375 THR THR A . n A 1 324 ALA 324 376 376 ALA ALA A . n A 1 325 ALA 325 377 377 ALA ALA A . n A 1 326 SER 326 378 378 SER SER A . n A 1 327 SER 327 379 379 SER SER A . n A 1 328 ASN 328 380 380 ASN ASN A . n A 1 329 MET 329 381 381 MET MET A . n A 1 330 VAL 330 382 382 VAL VAL A . n A 1 331 TYR 331 383 383 TYR TYR A . n A 1 332 VAL 332 384 384 VAL VAL A . n A 1 333 THR 333 385 385 THR THR A . n A 1 334 SER 334 386 386 SER SER A . n A 1 335 HIS 335 387 387 HIS HIS A . n A 1 336 THR 336 388 388 THR THR A . n A 1 337 ARG 337 389 389 ARG ARG A . n A 1 338 PRO 338 390 390 PRO PRO A . n A 1 339 ASP 339 391 391 ASP ASP A . n A 1 340 HIS 340 392 392 HIS HIS A . n A 1 341 GLU 341 393 393 GLU GLU A . n A 1 342 THR 342 394 394 THR THR A . n A 1 343 LYS 343 395 395 LYS LYS A . n A 1 344 CYS 344 396 396 CYS CYS A . n A 1 345 PRO 345 397 397 PRO PRO A . n A 1 346 PRO 346 398 398 PRO PRO A . n A 1 347 ARG 347 399 399 ARG ARG A . n A 1 348 GLU 348 400 400 GLU GLU A . n A 1 349 PRO 349 401 401 PRO PRO A . n A 1 350 LEU 350 402 402 LEU LEU A . n A 1 351 LYS 351 403 403 LYS LYS A . n A 1 352 ASN 352 404 404 ASN ASN A . n A 1 353 VAL 353 405 405 VAL VAL A . n A 1 354 ARG 354 406 406 ARG ARG A . n A 1 355 TRP 355 407 407 TRP TRP A . n A 1 356 GLY 356 408 408 GLY GLY A . n A 1 357 VAL 357 409 409 VAL VAL A . n A 1 358 VAL 358 410 410 VAL VAL A . n A 1 359 SER 359 411 411 SER SER A . n A 1 360 LYS 360 412 412 LYS LYS A . n A 1 361 GLY 361 413 413 GLY GLY A . n A 1 362 LYS 362 414 414 LYS LYS A . n A 1 363 TYR 363 415 415 TYR TYR A . n A 1 364 CYS 364 416 416 CYS CYS A . n A 1 365 LYS 365 417 417 LYS LYS A . n A 1 366 PRO 366 418 418 PRO PRO A . n A 1 367 MET 367 419 419 MET MET A . n A 1 368 ASN 368 420 420 ASN ASN A . n A 1 369 ALA 369 421 421 ALA ALA A . n A 1 370 ARG 370 422 422 ARG ARG A . n A 1 371 ALA 371 423 423 ALA ALA A . n A 1 372 SER 372 424 424 SER SER A . n A 1 373 LEU 373 425 425 LEU LEU A . n A 1 374 SER 374 426 426 SER SER A . n A 1 375 ASN 375 427 427 ASN ASN A . n A 1 376 ALA 376 428 428 ALA ALA A . n A 1 377 THR 377 429 429 THR THR A . n A 1 378 ALA 378 430 430 ALA ALA A . n A 1 379 GLU 379 431 431 GLU GLU A . n A 1 380 GLN 380 432 432 GLN GLN A . n A 1 381 CYS 381 433 433 CYS CYS A . n A 1 382 GLY 382 434 434 GLY GLY A . n A 1 383 GLN 383 435 435 GLN GLN A . n A 1 384 ARG 384 436 436 ARG ARG A . n A 1 385 LEU 385 437 437 LEU LEU A . n A 1 386 PHE 386 438 438 PHE PHE A . n A 1 387 MET 387 439 439 MET MET A . n A 1 388 LEU 388 440 440 LEU LEU A . n A 1 389 SER 389 441 441 SER SER A . n A 1 390 SER 390 442 442 SER SER A . n A 1 391 ALA 391 443 443 ALA ALA A . n A 1 392 ASP 392 444 444 ASP ASP A . n A 1 393 GLY 393 445 445 GLY GLY A . n A 1 394 SER 394 446 446 SER SER A . n A 1 395 SER 395 447 447 SER SER A . n A 1 396 LEU 396 448 448 LEU LEU A . n A 1 397 SER 397 449 449 SER SER A . n A 1 398 SER 398 450 450 SER SER A . n A 1 399 GLN 399 451 451 GLN GLN A . n A 1 400 VAL 400 452 452 VAL VAL A . n A 1 401 ARG 401 453 453 ARG ARG A . n A 1 402 GLY 402 454 454 GLY GLY A . n A 1 403 TYR 403 455 455 TYR TYR A . n A 1 404 HIS 404 456 456 HIS HIS A . n A 1 405 TRP 405 457 457 TRP TRP A . n A 1 406 ALA 406 458 458 ALA ALA A . n A 1 407 THR 407 459 459 THR THR A . n A 1 408 PHE 408 460 460 PHE PHE A . n A 1 409 VAL 409 461 461 VAL VAL A . n A 1 410 ALA 410 462 462 ALA ALA A . n A 1 411 THR 411 463 463 THR THR A . n A 1 412 ASP 412 464 464 ASP ASP A . n A 1 413 CYS 413 465 465 CYS CYS A . n A 1 414 ASN 414 466 466 ASN ASN A . n A 1 415 MET 415 467 467 MET MET A . n A 1 416 GLY 416 468 468 GLY GLY A . n A 1 417 GLU 417 469 469 GLU GLU A . n A 1 418 SER 418 470 470 SER SER A . n A 1 419 CYS 419 471 471 CYS CYS A . n A 1 420 ALA 420 472 472 ALA ALA A . n A 1 421 ALA 421 473 473 ALA ALA A . n A 1 422 THR 422 474 474 THR THR A . n A 1 423 ALA 423 475 475 ALA ALA A . n A 1 424 ARG 424 476 476 ARG ARG A . n A 1 425 GLY 425 477 477 GLY GLY A . n A 1 426 LYS 426 478 478 LYS LYS A . n A 1 427 CYS 427 479 479 CYS CYS A . n A 1 428 PHE 428 480 480 PHE PHE A . n A 1 429 PHE 429 481 481 PHE PHE A . n A 1 430 TYR 430 482 482 TYR TYR A . n A 1 431 SER 431 483 483 SER SER A . n A 1 432 THR 432 484 484 THR THR A . n A 1 433 VAL 433 485 485 VAL VAL A . n A 1 434 PRO 434 486 486 PRO PRO A . n A 1 435 GLU 435 487 487 GLU GLU A . n A 1 436 CYS 436 488 488 CYS CYS A . n A 1 437 LEU 437 489 489 LEU LEU A . n A 1 438 ILE 438 490 490 ILE ILE A . n A 1 439 HIS 439 491 491 HIS HIS A . n A 1 440 SER 440 492 492 SER SER A . n A 1 441 PRO 441 493 493 PRO PRO A . n A 1 442 THR 442 494 494 THR THR A . n A 1 443 THR 443 495 495 THR THR A . n A 1 444 MET 444 496 496 MET MET A . n A 1 445 ALA 445 497 497 ALA ALA A . n A 1 446 PHE 446 498 498 PHE PHE A . n A 1 447 THR 447 499 499 THR THR A . n A 1 448 SER 448 500 500 SER SER A . n A 1 449 LEU 449 501 501 LEU LEU A . n A 1 450 SER 450 502 502 SER SER A . n A 1 451 ALA 451 503 503 ALA ALA A . n A 1 452 VAL 452 504 504 VAL VAL A . n A 1 453 ASP 453 505 505 ASP ASP A . n A 1 454 PRO 454 506 506 PRO PRO A . n A 1 455 SER 455 507 507 SER SER A . n A 1 456 ILE 456 508 508 ILE ILE A . n A 1 457 ALA 457 509 509 ALA ALA A . n A 1 458 ILE 458 510 510 ILE ILE A . n A 1 459 ASP 459 511 511 ASP ASP A . n A 1 460 PRO 460 512 512 PRO PRO A . n A 1 461 ASP 461 513 513 ASP ASP A . n A 1 462 SER 462 514 514 SER SER A . n A 1 463 ILE 463 515 515 ILE ILE A . n A 1 464 ALA 464 516 516 ALA ALA A . n A 1 465 VAL 465 517 517 VAL VAL A . n A 1 466 LEU 466 518 518 LEU LEU A . n A 1 467 PRO 467 519 519 PRO PRO A . n A 1 468 GLU 468 520 520 GLU GLU A . n A 1 469 ASP 469 521 521 ASP ASP A . n A 1 470 LYS 470 522 522 LYS LYS A . n A 1 471 CYS 471 523 523 CYS CYS A . n A 1 472 VAL 472 524 524 VAL VAL A . n A 1 473 SER 473 525 ? ? ? A . n A 1 474 VAL 474 526 ? ? ? A . n A 1 475 ASP 475 527 ? ? ? A . n A 1 476 CYS 476 528 ? ? ? A . n A 1 477 GLY 477 529 ? ? ? A . n A 1 478 ALA 478 530 ? ? ? A . n A 1 479 HIS 479 531 ? ? ? A . n A 1 480 GLY 480 532 ? ? ? A . n A 1 481 THR 481 533 ? ? ? A . n A 1 482 CYS 482 534 ? ? ? A . n A 1 483 ASP 483 535 ? ? ? A . n A 1 484 VAL 484 536 ? ? ? A . n A 1 485 ALA 485 537 ? ? ? A . n A 1 486 THR 486 538 ? ? ? A . n A 1 487 GLY 487 539 ? ? ? A . n A 1 488 LYS 488 540 ? ? ? A . n A 1 489 CYS 489 541 ? ? ? A . n A 1 490 VAL 490 542 ? ? ? A . n A 1 491 CYS 491 543 ? ? ? A . n A 1 492 GLU 492 544 ? ? ? A . n A 1 493 PRO 493 545 ? ? ? A . n A 1 494 GLY 494 546 ? ? ? A . n A 1 495 PHE 495 547 ? ? ? A . n A 1 496 THR 496 548 ? ? ? A . n A 1 497 GLY 497 549 ? ? ? A . n A 1 498 GLU 498 550 ? ? ? A . n A 1 499 ARG 499 551 ? ? ? A . n A 1 500 CYS 500 552 ? ? ? A . n A 1 501 ASP 501 553 ? ? ? A . n A 1 502 ALA 502 554 ? ? ? A . n A 1 503 ALA 503 555 ? ? ? A . n A 1 504 ALA 504 556 ? ? ? A . n A 1 505 LEU 505 557 ? ? ? A . n A 1 506 VAL 506 558 ? ? ? A . n A 1 507 PRO 507 559 ? ? ? A . n A 1 508 ARG 508 560 ? ? ? A . n B 2 1 GLY 1 1288 ? ? ? C . n B 2 2 SER 2 1289 ? ? ? C . n B 2 3 ALA 3 1290 ? ? ? C . n B 2 4 SER 4 1291 ? ? ? C . n B 2 5 GLN 5 1292 ? ? ? C . n B 2 6 ILE 6 1293 1293 ILE ILE C . n B 2 7 VAL 7 1294 1294 VAL VAL C . n B 2 8 GLN 8 1295 1295 GLN GLN C . n B 2 9 ASN 9 1296 1296 ASN ASN C . n B 2 10 GLN 10 1297 1297 GLN GLN C . n B 2 11 SER 11 1298 1298 SER SER C . n B 2 12 SER 12 1299 1299 SER SER C . n B 2 13 LEU 13 1300 1300 LEU LEU C . n B 2 14 ALA 14 1301 1301 ALA ALA C . n B 2 15 PRO 15 1302 1302 PRO PRO C . n B 2 16 GLU 16 1303 1303 GLU GLU C . n B 2 17 LEU 17 1304 1304 LEU LEU C . n B 2 18 SER 18 1305 1305 SER SER C . n B 2 19 GLY 19 1306 1306 GLY GLY C . n B 2 20 CYS 20 1307 1307 CYS CYS C . n B 2 21 PRO 21 1308 1308 PRO PRO C . n B 2 22 PRO 22 1309 1309 PRO PRO C . n B 2 23 MET 23 1310 1310 MET MET C . n B 2 24 GLY 24 1311 1311 GLY GLY C . n B 2 25 ILE 25 1312 1312 ILE ILE C . n B 2 26 CYS 26 1313 1313 CYS CYS C . n B 2 27 MET 27 1314 1314 MET MET C . n B 2 28 ASP 28 1315 1315 ASP ASP C . n B 2 29 GLY 29 1316 1316 GLY GLY C . n B 2 30 THR 30 1317 1317 THR THR C . n B 2 31 ILE 31 1318 1318 ILE ILE C . n B 2 32 GLY 32 1319 1319 GLY GLY C . n B 2 33 ASP 33 1320 1320 ASP ASP C . n B 2 34 PRO 34 1321 1321 PRO PRO C . n B 2 35 ILE 35 1322 1322 ILE ILE C . n B 2 36 ALA 36 1323 1323 ALA ALA C . n B 2 37 SER 37 1324 1324 SER SER C . n C 1 1 GLY 1 53 ? ? ? B . n C 1 2 SER 2 54 ? ? ? B . n C 1 3 ALA 3 55 ? ? ? B . n C 1 4 MET 4 56 ? ? ? B . n C 1 5 GLY 5 57 ? ? ? B . n C 1 6 SER 6 58 ? ? ? B . n C 1 7 SER 7 59 59 SER SER B . n C 1 8 THR 8 60 60 THR THR B . n C 1 9 SER 9 61 61 SER SER B . n C 1 10 THR 10 62 62 THR THR B . n C 1 11 SER 11 63 63 SER SER B . n C 1 12 ARG 12 64 64 ARG ARG B . n C 1 13 ALA 13 65 65 ALA ALA B . n C 1 14 THR 14 66 66 THR THR B . n C 1 15 TYR 15 67 67 TYR TYR B . n C 1 16 MET 16 68 68 MET MET B . n C 1 17 ASP 17 69 69 ASP ASP B . n C 1 18 ARG 18 70 70 ARG ARG B . n C 1 19 PHE 19 71 71 PHE PHE B . n C 1 20 ASN 20 72 72 ASN ASN B . n C 1 21 ILE 21 73 73 ILE ILE B . n C 1 22 PRO 22 74 74 PRO PRO B . n C 1 23 LYS 23 75 75 LYS LYS B . n C 1 24 ASN 24 76 76 ASN ASN B . n C 1 25 HIS 25 77 77 HIS HIS B . n C 1 26 VAL 26 78 78 VAL VAL B . n C 1 27 ASP 27 79 79 ASP ASP B . n C 1 28 LEU 28 80 80 LEU LEU B . n C 1 29 ILE 29 81 81 ILE ILE B . n C 1 30 TRP 30 82 82 TRP TRP B . n C 1 31 ASP 31 83 83 ASP ASP B . n C 1 32 LYS 32 84 84 LYS LYS B . n C 1 33 ASP 33 85 85 ASP ASP B . n C 1 34 GLY 34 86 86 GLY GLY B . n C 1 35 THR 35 87 87 THR THR B . n C 1 36 LYS 36 88 88 LYS LYS B . n C 1 37 SER 37 89 89 SER SER B . n C 1 38 HIS 38 90 90 HIS HIS B . n C 1 39 THR 39 91 91 THR THR B . n C 1 40 ARG 40 92 92 ARG ARG B . n C 1 41 GLY 41 93 93 GLY GLY B . n C 1 42 ASN 42 94 94 ASN ASN B . n C 1 43 THR 43 95 95 THR THR B . n C 1 44 THR 44 96 96 THR THR B . n C 1 45 TYR 45 97 97 TYR TYR B . n C 1 46 ARG 46 98 98 ARG ARG B . n C 1 47 TRP 47 99 99 TRP TRP B . n C 1 48 THR 48 100 100 THR THR B . n C 1 49 GLU 49 101 101 GLU GLU B . n C 1 50 ARG 50 102 102 ARG ARG B . n C 1 51 LYS 51 103 103 LYS LYS B . n C 1 52 SER 52 104 104 SER SER B . n C 1 53 ASN 53 105 105 ASN ASN B . n C 1 54 VAL 54 106 106 VAL VAL B . n C 1 55 GLY 55 107 107 GLY GLY B . n C 1 56 VAL 56 108 108 VAL VAL B . n C 1 57 TYR 57 109 109 TYR TYR B . n C 1 58 VAL 58 110 110 VAL VAL B . n C 1 59 GLY 59 111 111 GLY GLY B . n C 1 60 TYR 60 112 112 TYR TYR B . n C 1 61 SER 61 113 113 SER SER B . n C 1 62 GLU 62 114 114 GLU GLU B . n C 1 63 MET 63 115 115 MET MET B . n C 1 64 TYR 64 116 116 TYR TYR B . n C 1 65 ASP 65 117 117 ASP ASP B . n C 1 66 SER 66 118 118 SER SER B . n C 1 67 SER 67 119 119 SER SER B . n C 1 68 ALA 68 120 120 ALA ALA B . n C 1 69 GLN 69 121 121 GLN GLN B . n C 1 70 ALA 70 122 122 ALA ALA B . n C 1 71 TYR 71 123 123 TYR TYR B . n C 1 72 CYS 72 124 124 CYS CYS B . n C 1 73 GLN 73 125 125 GLN GLN B . n C 1 74 SER 74 126 126 SER SER B . n C 1 75 SER 75 127 127 SER SER B . n C 1 76 SER 76 128 128 SER SER B . n C 1 77 ALA 77 129 129 ALA ALA B . n C 1 78 LYS 78 130 130 LYS LYS B . n C 1 79 ILE 79 131 131 ILE ILE B . n C 1 80 ASP 80 132 132 ASP ASP B . n C 1 81 THR 81 133 133 THR THR B . n C 1 82 LYS 82 134 134 LYS LYS B . n C 1 83 THR 83 135 135 THR THR B . n C 1 84 THR 84 136 136 THR THR B . n C 1 85 VAL 85 137 137 VAL VAL B . n C 1 86 GLY 86 138 138 GLY GLY B . n C 1 87 ALA 87 139 139 ALA ALA B . n C 1 88 PRO 88 140 140 PRO PRO B . n C 1 89 TYR 89 141 141 TYR TYR B . n C 1 90 MET 90 142 142 MET MET B . n C 1 91 ALA 91 143 143 ALA ALA B . n C 1 92 ALA 92 144 144 ALA ALA B . n C 1 93 GLY 93 145 145 GLY GLY B . n C 1 94 ALA 94 146 146 ALA ALA B . n C 1 95 CYS 95 147 147 CYS CYS B . n C 1 96 PRO 96 148 148 PRO PRO B . n C 1 97 ASN 97 149 149 ASN ASN B . n C 1 98 TYR 98 150 150 TYR TYR B . n C 1 99 GLY 99 151 151 GLY GLY B . n C 1 100 LYS 100 152 152 LYS LYS B . n C 1 101 VAL 101 153 153 VAL VAL B . n C 1 102 ILE 102 154 154 ILE ILE B . n C 1 103 ALA 103 155 155 ALA ALA B . n C 1 104 PHE 104 156 156 PHE PHE B . n C 1 105 THR 105 157 157 THR THR B . n C 1 106 LYS 106 158 158 LYS LYS B . n C 1 107 ARG 107 159 159 ARG ARG B . n C 1 108 ASP 108 160 160 ASP ASP B . n C 1 109 GLY 109 161 161 GLY GLY B . n C 1 110 SER 110 162 162 SER SER B . n C 1 111 ARG 111 163 163 ARG ARG B . n C 1 112 SER 112 164 164 SER SER B . n C 1 113 ASP 113 165 165 ASP ASP B . n C 1 114 MET 114 166 166 MET MET B . n C 1 115 THR 115 167 167 THR THR B . n C 1 116 ARG 116 168 168 ARG ARG B . n C 1 117 TRP 117 169 169 TRP TRP B . n C 1 118 LYS 118 170 170 LYS LYS B . n C 1 119 ASN 119 171 171 ASN ASN B . n C 1 120 GLU 120 172 172 GLU GLU B . n C 1 121 ILE 121 173 173 ILE ILE B . n C 1 122 HIS 122 174 174 HIS HIS B . n C 1 123 ALA 123 175 175 ALA ALA B . n C 1 124 ASN 124 176 176 ASN ASN B . n C 1 125 VAL 125 177 177 VAL VAL B . n C 1 126 MET 126 178 178 MET MET B . n C 1 127 PRO 127 179 179 PRO PRO B . n C 1 128 HIS 128 180 180 HIS HIS B . n C 1 129 SER 129 181 181 SER SER B . n C 1 130 THR 130 182 182 THR THR B . n C 1 131 THR 131 183 183 THR THR B . n C 1 132 SER 132 184 184 SER SER B . n C 1 133 CYS 133 185 185 CYS CYS B . n C 1 134 ALA 134 186 186 ALA ALA B . n C 1 135 SER 135 187 187 SER SER B . n C 1 136 ARG 136 188 188 ARG ARG B . n C 1 137 ALA 137 189 189 ALA ALA B . n C 1 138 ASP 138 190 190 ASP ASP B . n C 1 139 PRO 139 191 191 PRO PRO B . n C 1 140 GLY 140 192 192 GLY GLY B . n C 1 141 ALA 141 193 193 ALA ALA B . n C 1 142 ALA 142 194 194 ALA ALA B . n C 1 143 GLU 143 195 195 GLU GLU B . n C 1 144 VAL 144 196 196 VAL VAL B . n C 1 145 ALA 145 197 197 ALA ALA B . n C 1 146 LYS 146 198 198 LYS LYS B . n C 1 147 SER 147 199 199 SER SER B . n C 1 148 ILE 148 200 200 ILE ILE B . n C 1 149 GLU 149 201 201 GLU GLU B . n C 1 150 GLY 150 202 202 GLY GLY B . n C 1 151 PHE 151 203 203 PHE PHE B . n C 1 152 ALA 152 204 204 ALA ALA B . n C 1 153 MET 153 205 205 MET MET B . n C 1 154 TYR 154 206 206 TYR TYR B . n C 1 155 ALA 155 207 207 ALA ALA B . n C 1 156 GLY 156 208 208 GLY GLY B . n C 1 157 TYR 157 209 209 TYR TYR B . n C 1 158 LEU 158 210 210 LEU LEU B . n C 1 159 THR 159 211 211 THR THR B . n C 1 160 HIS 160 212 212 HIS HIS B . n C 1 161 CYS 161 213 213 CYS CYS B . n C 1 162 PRO 162 214 214 PRO PRO B . n C 1 163 TYR 163 215 215 TYR TYR B . n C 1 164 ASN 164 216 216 ASN ASN B . n C 1 165 VAL 165 217 217 VAL VAL B . n C 1 166 ASN 166 218 218 ASN ASN B . n C 1 167 VAL 167 219 219 VAL VAL B . n C 1 168 TYR 168 220 220 TYR TYR B . n C 1 169 ARG 169 221 221 ARG ARG B . n C 1 170 GLN 170 222 222 GLN GLN B . n C 1 171 ASP 171 223 223 ASP ASP B . n C 1 172 MET 172 224 224 MET MET B . n C 1 173 VAL 173 225 225 VAL VAL B . n C 1 174 THR 174 226 226 THR THR B . n C 1 175 ASP 175 227 227 ASP ASP B . n C 1 176 LYS 176 228 228 LYS LYS B . n C 1 177 GLU 177 229 229 GLU GLU B . n C 1 178 PHE 178 230 230 PHE PHE B . n C 1 179 ASP 179 231 231 ASP ASP B . n C 1 180 SER 180 232 232 SER SER B . n C 1 181 THR 181 233 233 THR THR B . n C 1 182 VAL 182 234 234 VAL VAL B . n C 1 183 CYS 183 235 235 CYS CYS B . n C 1 184 ASN 184 236 236 ASN ASN B . n C 1 185 PHE 185 237 237 PHE PHE B . n C 1 186 VAL 186 238 238 VAL VAL B . n C 1 187 THR 187 239 239 THR THR B . n C 1 188 GLU 188 240 240 GLU GLU B . n C 1 189 SER 189 241 241 SER SER B . n C 1 190 ASN 190 242 242 ASN ASN B . n C 1 191 PRO 191 243 243 PRO PRO B . n C 1 192 LEU 192 244 244 LEU LEU B . n C 1 193 ARG 193 245 245 ARG ARG B . n C 1 194 PHE 194 246 246 PHE PHE B . n C 1 195 LEU 195 247 247 LEU LEU B . n C 1 196 ASP 196 248 248 ASP ASP B . n C 1 197 THR 197 249 249 THR THR B . n C 1 198 THR 198 250 250 THR THR B . n C 1 199 GLN 199 251 251 GLN GLN B . n C 1 200 ARG 200 252 252 ARG ARG B . n C 1 201 GLN 201 253 253 GLN GLN B . n C 1 202 SER 202 254 254 SER SER B . n C 1 203 THR 203 255 255 THR THR B . n C 1 204 GLN 204 256 256 GLN GLN B . n C 1 205 PRO 205 257 257 PRO PRO B . n C 1 206 TYR 206 258 258 TYR TYR B . n C 1 207 THR 207 259 259 THR THR B . n C 1 208 GLU 208 260 260 GLU GLU B . n C 1 209 TYR 209 261 261 TYR TYR B . n C 1 210 ALA 210 262 262 ALA ALA B . n C 1 211 PHE 211 263 263 PHE PHE B . n C 1 212 HIS 212 264 264 HIS HIS B . n C 1 213 GLY 213 265 265 GLY GLY B . n C 1 214 LYS 214 266 266 LYS LYS B . n C 1 215 GLY 215 267 267 GLY GLY B . n C 1 216 GLY 216 268 268 GLY GLY B . n C 1 217 HIS 217 269 269 HIS HIS B . n C 1 218 LYS 218 270 270 LYS LYS B . n C 1 219 GLY 219 271 271 GLY GLY B . n C 1 220 TYR 220 272 272 TYR TYR B . n C 1 221 ASP 221 273 273 ASP ASP B . n C 1 222 TYR 222 274 274 TYR TYR B . n C 1 223 LYS 223 275 275 LYS LYS B . n C 1 224 GLY 224 276 276 GLY GLY B . n C 1 225 GLN 225 277 277 GLN GLN B . n C 1 226 THR 226 278 278 THR THR B . n C 1 227 SER 227 279 279 SER SER B . n C 1 228 HIS 228 280 280 HIS HIS B . n C 1 229 VAL 229 281 281 VAL VAL B . n C 1 230 GLY 230 282 282 GLY GLY B . n C 1 231 CYS 231 283 283 CYS CYS B . n C 1 232 PRO 232 284 284 PRO PRO B . n C 1 233 PRO 233 285 285 PRO PRO B . n C 1 234 TYR 234 286 286 TYR TYR B . n C 1 235 ASN 235 287 287 ASN ASN B . n C 1 236 PRO 236 288 288 PRO PRO B . n C 1 237 PRO 237 289 289 PRO PRO B . n C 1 238 HIS 238 290 290 HIS HIS B . n C 1 239 VAL 239 291 291 VAL VAL B . n C 1 240 THR 240 292 292 THR THR B . n C 1 241 LYS 241 293 293 LYS LYS B . n C 1 242 GLY 242 294 294 GLY GLY B . n C 1 243 MET 243 295 295 MET MET B . n C 1 244 LYS 244 296 296 LYS LYS B . n C 1 245 ASP 245 297 297 ASP ASP B . n C 1 246 SER 246 298 298 SER SER B . n C 1 247 SER 247 299 299 SER SER B . n C 1 248 TRP 248 300 300 TRP TRP B . n C 1 249 ILE 249 301 301 ILE ILE B . n C 1 250 THR 250 302 302 THR THR B . n C 1 251 GLY 251 303 303 GLY GLY B . n C 1 252 PRO 252 304 304 PRO PRO B . n C 1 253 PHE 253 305 305 PHE PHE B . n C 1 254 GLU 254 306 306 GLU GLU B . n C 1 255 CYS 255 307 307 CYS CYS B . n C 1 256 SER 256 308 308 SER SER B . n C 1 257 ILE 257 309 309 ILE ILE B . n C 1 258 LEU 258 310 310 LEU LEU B . n C 1 259 SER 259 311 311 SER SER B . n C 1 260 ARG 260 312 312 ARG ARG B . n C 1 261 CYS 261 313 313 CYS CYS B . n C 1 262 THR 262 314 314 THR THR B . n C 1 263 THR 263 315 315 THR THR B . n C 1 264 HIS 264 316 316 HIS HIS B . n C 1 265 CYS 265 317 317 CYS CYS B . n C 1 266 TRP 266 318 318 TRP TRP B . n C 1 267 PRO 267 319 319 PRO PRO B . n C 1 268 TYR 268 320 320 TYR TYR B . n C 1 269 LYS 269 321 321 LYS LYS B . n C 1 270 SER 270 322 322 SER SER B . n C 1 271 GLY 271 323 323 GLY GLY B . n C 1 272 GLY 272 324 324 GLY GLY B . n C 1 273 ASN 273 325 325 ASN ASN B . n C 1 274 CYS 274 326 326 CYS CYS B . n C 1 275 PHE 275 327 327 PHE PHE B . n C 1 276 ARG 276 328 328 ARG ARG B . n C 1 277 SER 277 329 329 SER SER B . n C 1 278 LEU 278 330 330 LEU LEU B . n C 1 279 PRO 279 331 331 PRO PRO B . n C 1 280 ALA 280 332 332 ALA ALA B . n C 1 281 MET 281 333 333 MET MET B . n C 1 282 PHE 282 334 334 PHE PHE B . n C 1 283 ASP 283 335 335 ASP ASP B . n C 1 284 MET 284 336 336 MET MET B . n C 1 285 SER 285 337 337 SER SER B . n C 1 286 THR 286 338 338 THR THR B . n C 1 287 GLY 287 339 339 GLY GLY B . n C 1 288 GLU 288 340 340 GLU GLU B . n C 1 289 CYS 289 341 341 CYS CYS B . n C 1 290 ARG 290 342 342 ARG ARG B . n C 1 291 LEU 291 343 343 LEU LEU B . n C 1 292 LEU 292 344 344 LEU LEU B . n C 1 293 GLY 293 345 345 GLY GLY B . n C 1 294 TYR 294 346 346 TYR TYR B . n C 1 295 HIS 295 347 347 HIS HIS B . n C 1 296 THR 296 348 348 THR THR B . n C 1 297 GLN 297 349 349 GLN GLN B . n C 1 298 ASP 298 350 350 ASP ASP B . n C 1 299 PHE 299 351 351 PHE PHE B . n C 1 300 ARG 300 352 352 ARG ARG B . n C 1 301 SER 301 353 353 SER SER B . n C 1 302 SER 302 354 354 SER SER B . n C 1 303 THR 303 355 355 THR THR B . n C 1 304 CYS 304 356 356 CYS CYS B . n C 1 305 ALA 305 357 357 ALA ALA B . n C 1 306 GLU 306 358 358 GLU GLU B . n C 1 307 LEU 307 359 359 LEU LEU B . n C 1 308 THR 308 360 360 THR THR B . n C 1 309 THR 309 361 361 THR THR B . n C 1 310 ASP 310 362 362 ASP ASP B . n C 1 311 ASP 311 363 363 ASP ASP B . n C 1 312 THR 312 364 364 THR THR B . n C 1 313 ASN 313 365 365 ASN ASN B . n C 1 314 ALA 314 366 366 ALA ALA B . n C 1 315 PHE 315 367 367 PHE PHE B . n C 1 316 TYR 316 368 368 TYR TYR B . n C 1 317 CYS 317 369 369 CYS CYS B . n C 1 318 VAL 318 370 370 VAL VAL B . n C 1 319 ARG 319 371 371 ARG ARG B . n C 1 320 PRO 320 372 372 PRO PRO B . n C 1 321 MET 321 373 373 MET MET B . n C 1 322 LYS 322 374 374 LYS LYS B . n C 1 323 THR 323 375 375 THR THR B . n C 1 324 ALA 324 376 376 ALA ALA B . n C 1 325 ALA 325 377 377 ALA ALA B . n C 1 326 SER 326 378 378 SER SER B . n C 1 327 SER 327 379 379 SER SER B . n C 1 328 ASN 328 380 380 ASN ASN B . n C 1 329 MET 329 381 381 MET MET B . n C 1 330 VAL 330 382 382 VAL VAL B . n C 1 331 TYR 331 383 383 TYR TYR B . n C 1 332 VAL 332 384 384 VAL VAL B . n C 1 333 THR 333 385 385 THR THR B . n C 1 334 SER 334 386 386 SER SER B . n C 1 335 HIS 335 387 387 HIS HIS B . n C 1 336 THR 336 388 388 THR THR B . n C 1 337 ARG 337 389 389 ARG ARG B . n C 1 338 PRO 338 390 390 PRO PRO B . n C 1 339 ASP 339 391 391 ASP ASP B . n C 1 340 HIS 340 392 392 HIS HIS B . n C 1 341 GLU 341 393 393 GLU GLU B . n C 1 342 THR 342 394 394 THR THR B . n C 1 343 LYS 343 395 395 LYS LYS B . n C 1 344 CYS 344 396 396 CYS CYS B . n C 1 345 PRO 345 397 397 PRO PRO B . n C 1 346 PRO 346 398 398 PRO PRO B . n C 1 347 ARG 347 399 399 ARG ARG B . n C 1 348 GLU 348 400 400 GLU GLU B . n C 1 349 PRO 349 401 401 PRO PRO B . n C 1 350 LEU 350 402 402 LEU LEU B . n C 1 351 LYS 351 403 403 LYS LYS B . n C 1 352 ASN 352 404 404 ASN ASN B . n C 1 353 VAL 353 405 405 VAL VAL B . n C 1 354 ARG 354 406 406 ARG ARG B . n C 1 355 TRP 355 407 407 TRP TRP B . n C 1 356 GLY 356 408 408 GLY GLY B . n C 1 357 VAL 357 409 409 VAL VAL B . n C 1 358 VAL 358 410 410 VAL VAL B . n C 1 359 SER 359 411 411 SER SER B . n C 1 360 LYS 360 412 412 LYS LYS B . n C 1 361 GLY 361 413 413 GLY GLY B . n C 1 362 LYS 362 414 414 LYS LYS B . n C 1 363 TYR 363 415 415 TYR TYR B . n C 1 364 CYS 364 416 416 CYS CYS B . n C 1 365 LYS 365 417 417 LYS LYS B . n C 1 366 PRO 366 418 418 PRO PRO B . n C 1 367 MET 367 419 419 MET MET B . n C 1 368 ASN 368 420 420 ASN ASN B . n C 1 369 ALA 369 421 421 ALA ALA B . n C 1 370 ARG 370 422 422 ARG ARG B . n C 1 371 ALA 371 423 423 ALA ALA B . n C 1 372 SER 372 424 424 SER SER B . n C 1 373 LEU 373 425 425 LEU LEU B . n C 1 374 SER 374 426 426 SER SER B . n C 1 375 ASN 375 427 427 ASN ASN B . n C 1 376 ALA 376 428 428 ALA ALA B . n C 1 377 THR 377 429 429 THR THR B . n C 1 378 ALA 378 430 430 ALA ALA B . n C 1 379 GLU 379 431 431 GLU GLU B . n C 1 380 GLN 380 432 432 GLN GLN B . n C 1 381 CYS 381 433 433 CYS CYS B . n C 1 382 GLY 382 434 434 GLY GLY B . n C 1 383 GLN 383 435 435 GLN GLN B . n C 1 384 ARG 384 436 436 ARG ARG B . n C 1 385 LEU 385 437 437 LEU LEU B . n C 1 386 PHE 386 438 438 PHE PHE B . n C 1 387 MET 387 439 439 MET MET B . n C 1 388 LEU 388 440 440 LEU LEU B . n C 1 389 SER 389 441 441 SER SER B . n C 1 390 SER 390 442 442 SER SER B . n C 1 391 ALA 391 443 443 ALA ALA B . n C 1 392 ASP 392 444 444 ASP ASP B . n C 1 393 GLY 393 445 445 GLY GLY B . n C 1 394 SER 394 446 446 SER SER B . n C 1 395 SER 395 447 447 SER SER B . n C 1 396 LEU 396 448 448 LEU LEU B . n C 1 397 SER 397 449 449 SER SER B . n C 1 398 SER 398 450 450 SER SER B . n C 1 399 GLN 399 451 451 GLN GLN B . n C 1 400 VAL 400 452 452 VAL VAL B . n C 1 401 ARG 401 453 453 ARG ARG B . n C 1 402 GLY 402 454 454 GLY GLY B . n C 1 403 TYR 403 455 455 TYR TYR B . n C 1 404 HIS 404 456 456 HIS HIS B . n C 1 405 TRP 405 457 457 TRP TRP B . n C 1 406 ALA 406 458 458 ALA ALA B . n C 1 407 THR 407 459 459 THR THR B . n C 1 408 PHE 408 460 460 PHE PHE B . n C 1 409 VAL 409 461 461 VAL VAL B . n C 1 410 ALA 410 462 462 ALA ALA B . n C 1 411 THR 411 463 463 THR THR B . n C 1 412 ASP 412 464 464 ASP ASP B . n C 1 413 CYS 413 465 465 CYS CYS B . n C 1 414 ASN 414 466 466 ASN ASN B . n C 1 415 MET 415 467 467 MET MET B . n C 1 416 GLY 416 468 468 GLY GLY B . n C 1 417 GLU 417 469 469 GLU GLU B . n C 1 418 SER 418 470 470 SER SER B . n C 1 419 CYS 419 471 471 CYS CYS B . n C 1 420 ALA 420 472 472 ALA ALA B . n C 1 421 ALA 421 473 473 ALA ALA B . n C 1 422 THR 422 474 474 THR THR B . n C 1 423 ALA 423 475 475 ALA ALA B . n C 1 424 ARG 424 476 476 ARG ARG B . n C 1 425 GLY 425 477 477 GLY GLY B . n C 1 426 LYS 426 478 478 LYS LYS B . n C 1 427 CYS 427 479 479 CYS CYS B . n C 1 428 PHE 428 480 480 PHE PHE B . n C 1 429 PHE 429 481 481 PHE PHE B . n C 1 430 TYR 430 482 482 TYR TYR B . n C 1 431 SER 431 483 483 SER SER B . n C 1 432 THR 432 484 484 THR THR B . n C 1 433 VAL 433 485 485 VAL VAL B . n C 1 434 PRO 434 486 486 PRO PRO B . n C 1 435 GLU 435 487 487 GLU GLU B . n C 1 436 CYS 436 488 488 CYS CYS B . n C 1 437 LEU 437 489 489 LEU LEU B . n C 1 438 ILE 438 490 490 ILE ILE B . n C 1 439 HIS 439 491 491 HIS HIS B . n C 1 440 SER 440 492 492 SER SER B . n C 1 441 PRO 441 493 493 PRO PRO B . n C 1 442 THR 442 494 494 THR THR B . n C 1 443 THR 443 495 495 THR THR B . n C 1 444 MET 444 496 496 MET MET B . n C 1 445 ALA 445 497 497 ALA ALA B . n C 1 446 PHE 446 498 498 PHE PHE B . n C 1 447 THR 447 499 499 THR THR B . n C 1 448 SER 448 500 500 SER SER B . n C 1 449 LEU 449 501 501 LEU LEU B . n C 1 450 SER 450 502 502 SER SER B . n C 1 451 ALA 451 503 503 ALA ALA B . n C 1 452 VAL 452 504 504 VAL VAL B . n C 1 453 ASP 453 505 505 ASP ASP B . n C 1 454 PRO 454 506 506 PRO PRO B . n C 1 455 SER 455 507 507 SER SER B . n C 1 456 ILE 456 508 508 ILE ILE B . n C 1 457 ALA 457 509 509 ALA ALA B . n C 1 458 ILE 458 510 510 ILE ILE B . n C 1 459 ASP 459 511 511 ASP ASP B . n C 1 460 PRO 460 512 512 PRO PRO B . n C 1 461 ASP 461 513 513 ASP ASP B . n C 1 462 SER 462 514 514 SER SER B . n C 1 463 ILE 463 515 515 ILE ILE B . n C 1 464 ALA 464 516 516 ALA ALA B . n C 1 465 VAL 465 517 517 VAL VAL B . n C 1 466 LEU 466 518 518 LEU LEU B . n C 1 467 PRO 467 519 519 PRO PRO B . n C 1 468 GLU 468 520 520 GLU GLU B . n C 1 469 ASP 469 521 521 ASP ASP B . n C 1 470 LYS 470 522 522 LYS LYS B . n C 1 471 CYS 471 523 523 CYS CYS B . n C 1 472 VAL 472 524 524 VAL VAL B . n C 1 473 SER 473 525 ? ? ? B . n C 1 474 VAL 474 526 ? ? ? B . n C 1 475 ASP 475 527 ? ? ? B . n C 1 476 CYS 476 528 ? ? ? B . n C 1 477 GLY 477 529 ? ? ? B . n C 1 478 ALA 478 530 ? ? ? B . n C 1 479 HIS 479 531 ? ? ? B . n C 1 480 GLY 480 532 ? ? ? B . n C 1 481 THR 481 533 ? ? ? B . n C 1 482 CYS 482 534 ? ? ? B . n C 1 483 ASP 483 535 ? ? ? B . n C 1 484 VAL 484 536 ? ? ? B . n C 1 485 ALA 485 537 ? ? ? B . n C 1 486 THR 486 538 ? ? ? B . n C 1 487 GLY 487 539 ? ? ? B . n C 1 488 LYS 488 540 ? ? ? B . n C 1 489 CYS 489 541 ? ? ? B . n C 1 490 VAL 490 542 ? ? ? B . n C 1 491 CYS 491 543 ? ? ? B . n C 1 492 GLU 492 544 ? ? ? B . n C 1 493 PRO 493 545 ? ? ? B . n C 1 494 GLY 494 546 ? ? ? B . n C 1 495 PHE 495 547 ? ? ? B . n C 1 496 THR 496 548 ? ? ? B . n C 1 497 GLY 497 549 ? ? ? B . n C 1 498 GLU 498 550 ? ? ? B . n C 1 499 ARG 499 551 ? ? ? B . n C 1 500 CYS 500 552 ? ? ? B . n C 1 501 ASP 501 553 ? ? ? B . n C 1 502 ALA 502 554 ? ? ? B . n C 1 503 ALA 503 555 ? ? ? B . n C 1 504 ALA 504 556 ? ? ? B . n C 1 505 LEU 505 557 ? ? ? B . n C 1 506 VAL 506 558 ? ? ? B . n C 1 507 PRO 507 559 ? ? ? B . n C 1 508 ARG 508 560 ? ? ? B . n D 2 1 GLY 1 1288 ? ? ? D . n D 2 2 SER 2 1289 ? ? ? D . n D 2 3 ALA 3 1290 ? ? ? D . n D 2 4 SER 4 1291 ? ? ? D . n D 2 5 GLN 5 1292 ? ? ? D . n D 2 6 ILE 6 1293 ? ? ? D . n D 2 7 VAL 7 1294 1294 VAL VAL D . n D 2 8 GLN 8 1295 1295 GLN GLN D . n D 2 9 ASN 9 1296 1296 ASN ASN D . n D 2 10 GLN 10 1297 1297 GLN GLN D . n D 2 11 SER 11 1298 1298 SER SER D . n D 2 12 SER 12 1299 1299 SER SER D . n D 2 13 LEU 13 1300 1300 LEU LEU D . n D 2 14 ALA 14 1301 1301 ALA ALA D . n D 2 15 PRO 15 1302 1302 PRO PRO D . n D 2 16 GLU 16 1303 1303 GLU GLU D . n D 2 17 LEU 17 1304 1304 LEU LEU D . n D 2 18 SER 18 1305 1305 SER SER D . n D 2 19 GLY 19 1306 1306 GLY GLY D . n D 2 20 CYS 20 1307 1307 CYS CYS D . n D 2 21 PRO 21 1308 1308 PRO PRO D . n D 2 22 PRO 22 1309 1309 PRO PRO D . n D 2 23 MET 23 1310 1310 MET MET D . n D 2 24 GLY 24 1311 1311 GLY GLY D . n D 2 25 ILE 25 1312 1312 ILE ILE D . n D 2 26 CYS 26 1313 1313 CYS CYS D . n D 2 27 MET 27 1314 1314 MET MET D . n D 2 28 ASP 28 1315 1315 ASP ASP D . n D 2 29 GLY 29 1316 1316 GLY GLY D . n D 2 30 THR 30 1317 1317 THR THR D . n D 2 31 ILE 31 1318 1318 ILE ILE D . n D 2 32 GLY 32 1319 1319 GLY GLY D . n D 2 33 ASP 33 1320 1320 ASP ASP D . n D 2 34 PRO 34 1321 1321 PRO PRO D . n D 2 35 ILE 35 1322 1322 ILE ILE D . n D 2 36 ALA 36 1323 1323 ALA ALA D . n D 2 37 SER 37 1324 1324 SER SER D . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code E 3 GOL 1 601 1 GOL GOL A . F 3 GOL 1 602 2 GOL GOL A . G 3 GOL 1 603 4 GOL GOL A . H 4 SO4 1 604 1 SO4 SO4 A . I 4 SO4 1 605 2 SO4 SO4 A . J 4 SO4 1 606 3 SO4 SO4 A . K 5 NAG 1 601 1 NAG NAG B . L 3 GOL 1 602 3 GOL GOL B . M 6 HOH 1 701 694 HOH HOH A . M 6 HOH 2 702 957 HOH HOH A . M 6 HOH 3 703 582 HOH HOH A . M 6 HOH 4 704 1250 HOH HOH A . M 6 HOH 5 705 1153 HOH HOH A . M 6 HOH 6 706 995 HOH HOH A . M 6 HOH 7 707 862 HOH HOH A . M 6 HOH 8 708 1069 HOH HOH A . M 6 HOH 9 709 505 HOH HOH A . M 6 HOH 10 710 1218 HOH HOH A . M 6 HOH 11 711 693 HOH HOH A . M 6 HOH 12 712 756 HOH HOH A . M 6 HOH 13 713 600 HOH HOH A . M 6 HOH 14 714 286 HOH HOH A . M 6 HOH 15 715 1276 HOH HOH A . M 6 HOH 16 716 886 HOH HOH A . M 6 HOH 17 717 205 HOH HOH A . M 6 HOH 18 718 219 HOH HOH A . M 6 HOH 19 719 368 HOH HOH A . M 6 HOH 20 720 810 HOH HOH A . M 6 HOH 21 721 1115 HOH HOH A . M 6 HOH 22 722 1280 HOH HOH A . M 6 HOH 23 723 591 HOH HOH A . M 6 HOH 24 724 103 HOH HOH A . M 6 HOH 25 725 900 HOH HOH A . M 6 HOH 26 726 298 HOH HOH A . M 6 HOH 27 727 139 HOH HOH A . M 6 HOH 28 728 193 HOH HOH A . M 6 HOH 29 729 553 HOH HOH A . M 6 HOH 30 730 386 HOH HOH A . M 6 HOH 31 731 244 HOH HOH A . M 6 HOH 32 732 176 HOH HOH A . M 6 HOH 33 733 18 HOH HOH A . M 6 HOH 34 734 598 HOH HOH A . M 6 HOH 35 735 631 HOH HOH A . M 6 HOH 36 736 427 HOH HOH A . M 6 HOH 37 737 636 HOH HOH A . M 6 HOH 38 738 1083 HOH HOH A . M 6 HOH 39 739 1071 HOH HOH A . M 6 HOH 40 740 1061 HOH HOH A . M 6 HOH 41 741 1076 HOH HOH A . M 6 HOH 42 742 245 HOH HOH A . M 6 HOH 43 743 297 HOH HOH A . M 6 HOH 44 744 733 HOH HOH A . M 6 HOH 45 745 221 HOH HOH A . M 6 HOH 46 746 310 HOH HOH A . M 6 HOH 47 747 203 HOH HOH A . M 6 HOH 48 748 365 HOH HOH A . M 6 HOH 49 749 279 HOH HOH A . M 6 HOH 50 750 520 HOH HOH A . M 6 HOH 51 751 867 HOH HOH A . M 6 HOH 52 752 413 HOH HOH A . M 6 HOH 53 753 311 HOH HOH A . M 6 HOH 54 754 304 HOH HOH A . M 6 HOH 55 755 758 HOH HOH A . M 6 HOH 56 756 587 HOH HOH A . M 6 HOH 57 757 869 HOH HOH A . M 6 HOH 58 758 532 HOH HOH A . M 6 HOH 59 759 1352 HOH HOH A . M 6 HOH 60 760 154 HOH HOH A . M 6 HOH 61 761 848 HOH HOH A . M 6 HOH 62 762 526 HOH HOH A . M 6 HOH 63 763 575 HOH HOH A . M 6 HOH 64 764 835 HOH HOH A . M 6 HOH 65 765 1024 HOH HOH A . M 6 HOH 66 766 570 HOH HOH A . M 6 HOH 67 767 745 HOH HOH A . M 6 HOH 68 768 924 HOH HOH A . M 6 HOH 69 769 187 HOH HOH A . M 6 HOH 70 770 25 HOH HOH A . M 6 HOH 71 771 392 HOH HOH A . M 6 HOH 72 772 440 HOH HOH A . M 6 HOH 73 773 339 HOH HOH A . M 6 HOH 74 774 559 HOH HOH A . M 6 HOH 75 775 468 HOH HOH A . M 6 HOH 76 776 472 HOH HOH A . M 6 HOH 77 777 415 HOH HOH A . M 6 HOH 78 778 1228 HOH HOH A . M 6 HOH 79 779 1356 HOH HOH A . M 6 HOH 80 780 243 HOH HOH A . M 6 HOH 81 781 21 HOH HOH A . M 6 HOH 82 782 828 HOH HOH A . M 6 HOH 83 783 43 HOH HOH A . M 6 HOH 84 784 372 HOH HOH A . M 6 HOH 85 785 211 HOH HOH A . M 6 HOH 86 786 721 HOH HOH A . M 6 HOH 87 787 1344 HOH HOH A . M 6 HOH 88 788 482 HOH HOH A . M 6 HOH 89 789 300 HOH HOH A . M 6 HOH 90 790 163 HOH HOH A . M 6 HOH 91 791 50 HOH HOH A . M 6 HOH 92 792 435 HOH HOH A . M 6 HOH 93 793 855 HOH HOH A . M 6 HOH 94 794 728 HOH HOH A . M 6 HOH 95 795 49 HOH HOH A . M 6 HOH 96 796 671 HOH HOH A . M 6 HOH 97 797 1311 HOH HOH A . M 6 HOH 98 798 1351 HOH HOH A . M 6 HOH 99 799 567 HOH HOH A . M 6 HOH 100 800 131 HOH HOH A . M 6 HOH 101 801 38 HOH HOH A . M 6 HOH 102 802 389 HOH HOH A . M 6 HOH 103 803 947 HOH HOH A . M 6 HOH 104 804 81 HOH HOH A . M 6 HOH 105 805 85 HOH HOH A . M 6 HOH 106 806 460 HOH HOH A . M 6 HOH 107 807 473 HOH HOH A . M 6 HOH 108 808 345 HOH HOH A . M 6 HOH 109 809 351 HOH HOH A . M 6 HOH 110 810 542 HOH HOH A . M 6 HOH 111 811 1109 HOH HOH A . M 6 HOH 112 812 336 HOH HOH A . M 6 HOH 113 813 276 HOH HOH A . M 6 HOH 114 814 478 HOH HOH A . M 6 HOH 115 815 603 HOH HOH A . M 6 HOH 116 816 462 HOH HOH A . M 6 HOH 117 817 489 HOH HOH A . M 6 HOH 118 818 548 HOH HOH A . M 6 HOH 119 819 1149 HOH HOH A . M 6 HOH 120 820 88 HOH HOH A . M 6 HOH 121 821 56 HOH HOH A . M 6 HOH 122 822 445 HOH HOH A . M 6 HOH 123 823 108 HOH HOH A . M 6 HOH 124 824 241 HOH HOH A . M 6 HOH 125 825 262 HOH HOH A . M 6 HOH 126 826 414 HOH HOH A . M 6 HOH 127 827 110 HOH HOH A . M 6 HOH 128 828 104 HOH HOH A . M 6 HOH 129 829 177 HOH HOH A . M 6 HOH 130 830 134 HOH HOH A . M 6 HOH 131 831 496 HOH HOH A . M 6 HOH 132 832 98 HOH HOH A . M 6 HOH 133 833 263 HOH HOH A . M 6 HOH 134 834 173 HOH HOH A . M 6 HOH 135 835 54 HOH HOH A . M 6 HOH 136 836 135 HOH HOH A . M 6 HOH 137 837 902 HOH HOH A . M 6 HOH 138 838 117 HOH HOH A . M 6 HOH 139 839 942 HOH HOH A . M 6 HOH 140 840 528 HOH HOH A . M 6 HOH 141 841 1029 HOH HOH A . M 6 HOH 142 842 228 HOH HOH A . M 6 HOH 143 843 299 HOH HOH A . M 6 HOH 144 844 816 HOH HOH A . M 6 HOH 145 845 217 HOH HOH A . M 6 HOH 146 846 240 HOH HOH A . M 6 HOH 147 847 1057 HOH HOH A . M 6 HOH 148 848 790 HOH HOH A . M 6 HOH 149 849 812 HOH HOH A . M 6 HOH 150 850 355 HOH HOH A . M 6 HOH 151 851 195 HOH HOH A . M 6 HOH 152 852 166 HOH HOH A . M 6 HOH 153 853 632 HOH HOH A . M 6 HOH 154 854 113 HOH HOH A . M 6 HOH 155 855 800 HOH HOH A . M 6 HOH 156 856 92 HOH HOH A . M 6 HOH 157 857 870 HOH HOH A . M 6 HOH 158 858 387 HOH HOH A . M 6 HOH 159 859 912 HOH HOH A . M 6 HOH 160 860 150 HOH HOH A . M 6 HOH 161 861 218 HOH HOH A . M 6 HOH 162 862 843 HOH HOH A . M 6 HOH 163 863 617 HOH HOH A . M 6 HOH 164 864 808 HOH HOH A . M 6 HOH 165 865 124 HOH HOH A . M 6 HOH 166 866 762 HOH HOH A . M 6 HOH 167 867 832 HOH HOH A . M 6 HOH 168 868 209 HOH HOH A . M 6 HOH 169 869 935 HOH HOH A . M 6 HOH 170 870 2 HOH HOH A . M 6 HOH 171 871 1217 HOH HOH A . M 6 HOH 172 872 933 HOH HOH A . M 6 HOH 173 873 876 HOH HOH A . M 6 HOH 174 874 329 HOH HOH A . M 6 HOH 175 875 499 HOH HOH A . M 6 HOH 176 876 438 HOH HOH A . M 6 HOH 177 877 747 HOH HOH A . M 6 HOH 178 878 417 HOH HOH A . M 6 HOH 179 879 963 HOH HOH A . M 6 HOH 180 880 42 HOH HOH A . M 6 HOH 181 881 467 HOH HOH A . M 6 HOH 182 882 401 HOH HOH A . M 6 HOH 183 883 1131 HOH HOH A . M 6 HOH 184 884 41 HOH HOH A . M 6 HOH 185 885 1222 HOH HOH A . M 6 HOH 186 886 362 HOH HOH A . M 6 HOH 187 887 239 HOH HOH A . M 6 HOH 188 888 143 HOH HOH A . M 6 HOH 189 889 794 HOH HOH A . M 6 HOH 190 890 464 HOH HOH A . M 6 HOH 191 891 323 HOH HOH A . M 6 HOH 192 892 985 HOH HOH A . M 6 HOH 193 893 379 HOH HOH A . M 6 HOH 194 894 247 HOH HOH A . M 6 HOH 195 895 114 HOH HOH A . M 6 HOH 196 896 755 HOH HOH A . M 6 HOH 197 897 1085 HOH HOH A . M 6 HOH 198 898 208 HOH HOH A . M 6 HOH 199 899 1227 HOH HOH A . M 6 HOH 200 900 384 HOH HOH A . M 6 HOH 201 901 91 HOH HOH A . M 6 HOH 202 902 458 HOH HOH A . M 6 HOH 203 903 475 HOH HOH A . M 6 HOH 204 904 822 HOH HOH A . M 6 HOH 205 905 144 HOH HOH A . M 6 HOH 206 906 213 HOH HOH A . M 6 HOH 207 907 986 HOH HOH A . M 6 HOH 208 908 1133 HOH HOH A . M 6 HOH 209 909 4 HOH HOH A . M 6 HOH 210 910 255 HOH HOH A . M 6 HOH 211 911 122 HOH HOH A . M 6 HOH 212 912 267 HOH HOH A . M 6 HOH 213 913 442 HOH HOH A . M 6 HOH 214 914 246 HOH HOH A . M 6 HOH 215 915 72 HOH HOH A . M 6 HOH 216 916 517 HOH HOH A . M 6 HOH 217 917 322 HOH HOH A . M 6 HOH 218 918 1005 HOH HOH A . M 6 HOH 219 919 409 HOH HOH A . M 6 HOH 220 920 194 HOH HOH A . M 6 HOH 221 921 726 HOH HOH A . M 6 HOH 222 922 73 HOH HOH A . M 6 HOH 223 923 885 HOH HOH A . M 6 HOH 224 924 1011 HOH HOH A . M 6 HOH 225 925 155 HOH HOH A . M 6 HOH 226 926 137 HOH HOH A . M 6 HOH 227 927 232 HOH HOH A . M 6 HOH 228 928 80 HOH HOH A . M 6 HOH 229 929 374 HOH HOH A . M 6 HOH 230 930 65 HOH HOH A . M 6 HOH 231 931 1096 HOH HOH A . M 6 HOH 232 932 781 HOH HOH A . M 6 HOH 233 933 346 HOH HOH A . M 6 HOH 234 934 236 HOH HOH A . M 6 HOH 235 935 19 HOH HOH A . M 6 HOH 236 936 326 HOH HOH A . M 6 HOH 237 937 220 HOH HOH A . M 6 HOH 238 938 561 HOH HOH A . M 6 HOH 239 939 424 HOH HOH A . M 6 HOH 240 940 395 HOH HOH A . M 6 HOH 241 941 979 HOH HOH A . M 6 HOH 242 942 11 HOH HOH A . M 6 HOH 243 943 37 HOH HOH A . M 6 HOH 244 944 803 HOH HOH A . M 6 HOH 245 945 614 HOH HOH A . M 6 HOH 246 946 836 HOH HOH A . M 6 HOH 247 947 95 HOH HOH A . M 6 HOH 248 948 238 HOH HOH A . M 6 HOH 249 949 576 HOH HOH A . M 6 HOH 250 950 62 HOH HOH A . M 6 HOH 251 951 12 HOH HOH A . M 6 HOH 252 952 102 HOH HOH A . M 6 HOH 253 953 635 HOH HOH A . M 6 HOH 254 954 911 HOH HOH A . M 6 HOH 255 955 1006 HOH HOH A . M 6 HOH 256 956 133 HOH HOH A . M 6 HOH 257 957 312 HOH HOH A . M 6 HOH 258 958 188 HOH HOH A . M 6 HOH 259 959 897 HOH HOH A . M 6 HOH 260 960 302 HOH HOH A . M 6 HOH 261 961 258 HOH HOH A . M 6 HOH 262 962 729 HOH HOH A . M 6 HOH 263 963 678 HOH HOH A . M 6 HOH 264 964 400 HOH HOH A . M 6 HOH 265 965 811 HOH HOH A . M 6 HOH 266 966 477 HOH HOH A . M 6 HOH 267 967 115 HOH HOH A . M 6 HOH 268 968 254 HOH HOH A . M 6 HOH 269 969 223 HOH HOH A . M 6 HOH 270 970 183 HOH HOH A . M 6 HOH 271 971 1062 HOH HOH A . M 6 HOH 272 972 378 HOH HOH A . M 6 HOH 273 973 865 HOH HOH A . M 6 HOH 274 974 965 HOH HOH A . M 6 HOH 275 975 453 HOH HOH A . M 6 HOH 276 976 7 HOH HOH A . M 6 HOH 277 977 765 HOH HOH A . M 6 HOH 278 978 506 HOH HOH A . M 6 HOH 279 979 380 HOH HOH A . M 6 HOH 280 980 815 HOH HOH A . M 6 HOH 281 981 511 HOH HOH A . M 6 HOH 282 982 1053 HOH HOH A . M 6 HOH 283 983 90 HOH HOH A . M 6 HOH 284 984 749 HOH HOH A . M 6 HOH 285 985 1027 HOH HOH A . M 6 HOH 286 986 109 HOH HOH A . M 6 HOH 287 987 1113 HOH HOH A . M 6 HOH 288 988 607 HOH HOH A . M 6 HOH 289 989 751 HOH HOH A . M 6 HOH 290 990 309 HOH HOH A . M 6 HOH 291 991 674 HOH HOH A . M 6 HOH 292 992 507 HOH HOH A . M 6 HOH 293 993 508 HOH HOH A . M 6 HOH 294 994 1360 HOH HOH A . M 6 HOH 295 995 44 HOH HOH A . M 6 HOH 296 996 623 HOH HOH A . M 6 HOH 297 997 918 HOH HOH A . M 6 HOH 298 998 563 HOH HOH A . M 6 HOH 299 999 761 HOH HOH A . M 6 HOH 300 1000 332 HOH HOH A . M 6 HOH 301 1001 714 HOH HOH A . M 6 HOH 302 1002 441 HOH HOH A . M 6 HOH 303 1003 1232 HOH HOH A . M 6 HOH 304 1004 77 HOH HOH A . M 6 HOH 305 1005 350 HOH HOH A . M 6 HOH 306 1006 536 HOH HOH A . M 6 HOH 307 1007 1288 HOH HOH A . M 6 HOH 308 1008 106 HOH HOH A . M 6 HOH 309 1009 711 HOH HOH A . M 6 HOH 310 1010 412 HOH HOH A . M 6 HOH 311 1011 825 HOH HOH A . M 6 HOH 312 1012 215 HOH HOH A . M 6 HOH 313 1013 1338 HOH HOH A . M 6 HOH 314 1014 474 HOH HOH A . M 6 HOH 315 1015 343 HOH HOH A . M 6 HOH 316 1016 1357 HOH HOH A . M 6 HOH 317 1017 746 HOH HOH A . M 6 HOH 318 1018 688 HOH HOH A . M 6 HOH 319 1019 637 HOH HOH A . M 6 HOH 320 1020 650 HOH HOH A . M 6 HOH 321 1021 252 HOH HOH A . M 6 HOH 322 1022 8 HOH HOH A . M 6 HOH 323 1023 752 HOH HOH A . M 6 HOH 324 1024 932 HOH HOH A . M 6 HOH 325 1025 233 HOH HOH A . M 6 HOH 326 1026 186 HOH HOH A . M 6 HOH 327 1027 234 HOH HOH A . M 6 HOH 328 1028 1118 HOH HOH A . M 6 HOH 329 1029 272 HOH HOH A . M 6 HOH 330 1030 463 HOH HOH A . M 6 HOH 331 1031 270 HOH HOH A . M 6 HOH 332 1032 321 HOH HOH A . M 6 HOH 333 1033 564 HOH HOH A . M 6 HOH 334 1034 59 HOH HOH A . M 6 HOH 335 1035 231 HOH HOH A . M 6 HOH 336 1036 1066 HOH HOH A . M 6 HOH 337 1037 382 HOH HOH A . M 6 HOH 338 1038 533 HOH HOH A . M 6 HOH 339 1039 235 HOH HOH A . M 6 HOH 340 1040 27 HOH HOH A . M 6 HOH 341 1041 1258 HOH HOH A . M 6 HOH 342 1042 169 HOH HOH A . M 6 HOH 343 1043 46 HOH HOH A . M 6 HOH 344 1044 1263 HOH HOH A . M 6 HOH 345 1045 1257 HOH HOH A . M 6 HOH 346 1046 541 HOH HOH A . M 6 HOH 347 1047 451 HOH HOH A . M 6 HOH 348 1048 16 HOH HOH A . M 6 HOH 349 1049 353 HOH HOH A . M 6 HOH 350 1050 66 HOH HOH A . M 6 HOH 351 1051 82 HOH HOH A . M 6 HOH 352 1052 827 HOH HOH A . M 6 HOH 353 1053 268 HOH HOH A . M 6 HOH 354 1054 534 HOH HOH A . M 6 HOH 355 1055 275 HOH HOH A . M 6 HOH 356 1056 943 HOH HOH A . M 6 HOH 357 1057 75 HOH HOH A . M 6 HOH 358 1058 352 HOH HOH A . M 6 HOH 359 1059 407 HOH HOH A . M 6 HOH 360 1060 418 HOH HOH A . M 6 HOH 361 1061 100 HOH HOH A . M 6 HOH 362 1062 789 HOH HOH A . M 6 HOH 363 1063 493 HOH HOH A . M 6 HOH 364 1064 1041 HOH HOH A . M 6 HOH 365 1065 1336 HOH HOH A . M 6 HOH 366 1066 83 HOH HOH A . M 6 HOH 367 1067 452 HOH HOH A . M 6 HOH 368 1068 74 HOH HOH A . M 6 HOH 369 1069 743 HOH HOH A . M 6 HOH 370 1070 151 HOH HOH A . M 6 HOH 371 1071 494 HOH HOH A . M 6 HOH 372 1072 754 HOH HOH A . M 6 HOH 373 1073 864 HOH HOH A . M 6 HOH 374 1074 627 HOH HOH A . M 6 HOH 375 1075 514 HOH HOH A . M 6 HOH 376 1076 1151 HOH HOH A . M 6 HOH 377 1077 621 HOH HOH A . M 6 HOH 378 1078 975 HOH HOH A . M 6 HOH 379 1079 687 HOH HOH A . M 6 HOH 380 1080 159 HOH HOH A . M 6 HOH 381 1081 651 HOH HOH A . M 6 HOH 382 1082 200 HOH HOH A . M 6 HOH 383 1083 196 HOH HOH A . M 6 HOH 384 1084 1212 HOH HOH A . M 6 HOH 385 1085 250 HOH HOH A . M 6 HOH 386 1086 174 HOH HOH A . M 6 HOH 387 1087 226 HOH HOH A . M 6 HOH 388 1088 201 HOH HOH A . M 6 HOH 389 1089 334 HOH HOH A . M 6 HOH 390 1090 772 HOH HOH A . M 6 HOH 391 1091 565 HOH HOH A . M 6 HOH 392 1092 45 HOH HOH A . M 6 HOH 393 1093 757 HOH HOH A . M 6 HOH 394 1094 676 HOH HOH A . M 6 HOH 395 1095 393 HOH HOH A . M 6 HOH 396 1096 14 HOH HOH A . M 6 HOH 397 1097 1198 HOH HOH A . M 6 HOH 398 1098 849 HOH HOH A . M 6 HOH 399 1099 170 HOH HOH A . M 6 HOH 400 1100 921 HOH HOH A . M 6 HOH 401 1101 257 HOH HOH A . M 6 HOH 402 1102 1362 HOH HOH A . M 6 HOH 403 1103 492 HOH HOH A . M 6 HOH 404 1104 447 HOH HOH A . M 6 HOH 405 1105 513 HOH HOH A . M 6 HOH 406 1106 283 HOH HOH A . M 6 HOH 407 1107 736 HOH HOH A . M 6 HOH 408 1108 190 HOH HOH A . M 6 HOH 409 1109 1239 HOH HOH A . M 6 HOH 410 1110 388 HOH HOH A . M 6 HOH 411 1111 731 HOH HOH A . M 6 HOH 412 1112 715 HOH HOH A . M 6 HOH 413 1113 327 HOH HOH A . M 6 HOH 414 1114 566 HOH HOH A . M 6 HOH 415 1115 1138 HOH HOH A . M 6 HOH 416 1116 52 HOH HOH A . M 6 HOH 417 1117 695 HOH HOH A . M 6 HOH 418 1118 461 HOH HOH A . M 6 HOH 419 1119 17 HOH HOH A . M 6 HOH 420 1120 306 HOH HOH A . M 6 HOH 421 1121 160 HOH HOH A . M 6 HOH 422 1122 599 HOH HOH A . M 6 HOH 423 1123 634 HOH HOH A . M 6 HOH 424 1124 1215 HOH HOH A . M 6 HOH 425 1125 69 HOH HOH A . M 6 HOH 426 1126 434 HOH HOH A . M 6 HOH 427 1127 1035 HOH HOH A . M 6 HOH 428 1128 879 HOH HOH A . M 6 HOH 429 1129 1236 HOH HOH A . M 6 HOH 430 1130 717 HOH HOH A . M 6 HOH 431 1131 840 HOH HOH A . M 6 HOH 432 1132 1225 HOH HOH A . M 6 HOH 433 1133 437 HOH HOH A . M 6 HOH 434 1134 36 HOH HOH A . M 6 HOH 435 1135 853 HOH HOH A . M 6 HOH 436 1136 968 HOH HOH A . M 6 HOH 437 1137 358 HOH HOH A . M 6 HOH 438 1138 732 HOH HOH A . M 6 HOH 439 1139 1240 HOH HOH A . M 6 HOH 440 1140 509 HOH HOH A . M 6 HOH 441 1141 1298 HOH HOH A . M 6 HOH 442 1142 727 HOH HOH A . M 6 HOH 443 1143 248 HOH HOH A . M 6 HOH 444 1144 579 HOH HOH A . M 6 HOH 445 1145 696 HOH HOH A . M 6 HOH 446 1146 1160 HOH HOH A . M 6 HOH 447 1147 1312 HOH HOH A . M 6 HOH 448 1148 361 HOH HOH A . M 6 HOH 449 1149 405 HOH HOH A . M 6 HOH 450 1150 796 HOH HOH A . M 6 HOH 451 1151 1077 HOH HOH A . M 6 HOH 452 1152 959 HOH HOH A . M 6 HOH 453 1153 813 HOH HOH A . M 6 HOH 454 1154 314 HOH HOH A . M 6 HOH 455 1155 1163 HOH HOH A . M 6 HOH 456 1156 34 HOH HOH A . M 6 HOH 457 1157 1117 HOH HOH A . M 6 HOH 458 1158 495 HOH HOH A . M 6 HOH 459 1159 284 HOH HOH A . M 6 HOH 460 1160 450 HOH HOH A . M 6 HOH 461 1161 1001 HOH HOH A . M 6 HOH 462 1162 1169 HOH HOH A . M 6 HOH 463 1163 806 HOH HOH A . M 6 HOH 464 1164 680 HOH HOH A . M 6 HOH 465 1165 1038 HOH HOH A . M 6 HOH 466 1166 485 HOH HOH A . M 6 HOH 467 1167 689 HOH HOH A . M 6 HOH 468 1168 834 HOH HOH A . M 6 HOH 469 1169 1086 HOH HOH A . M 6 HOH 470 1170 744 HOH HOH A . M 6 HOH 471 1171 459 HOH HOH A . M 6 HOH 472 1172 945 HOH HOH A . M 6 HOH 473 1173 1074 HOH HOH A . M 6 HOH 474 1174 1097 HOH HOH A . M 6 HOH 475 1175 838 HOH HOH A . M 6 HOH 476 1176 1155 HOH HOH A . M 6 HOH 477 1177 934 HOH HOH A . M 6 HOH 478 1178 487 HOH HOH A . M 6 HOH 479 1179 439 HOH HOH A . M 6 HOH 480 1180 1291 HOH HOH A . M 6 HOH 481 1181 903 HOH HOH A . M 6 HOH 482 1182 951 HOH HOH A . M 6 HOH 483 1183 1274 HOH HOH A . M 6 HOH 484 1184 618 HOH HOH A . M 6 HOH 485 1185 1186 HOH HOH A . M 6 HOH 486 1186 1269 HOH HOH A . M 6 HOH 487 1187 1050 HOH HOH A . M 6 HOH 488 1188 1226 HOH HOH A . M 6 HOH 489 1189 913 HOH HOH A . M 6 HOH 490 1190 1347 HOH HOH A . M 6 HOH 491 1191 1031 HOH HOH A . M 6 HOH 492 1192 871 HOH HOH A . M 6 HOH 493 1193 769 HOH HOH A . M 6 HOH 494 1194 773 HOH HOH A . M 6 HOH 495 1195 984 HOH HOH A . M 6 HOH 496 1196 1332 HOH HOH A . M 6 HOH 497 1197 966 HOH HOH A . M 6 HOH 498 1198 1355 HOH HOH A . M 6 HOH 499 1199 479 HOH HOH A . M 6 HOH 500 1200 668 HOH HOH A . M 6 HOH 501 1201 490 HOH HOH A . M 6 HOH 502 1202 655 HOH HOH A . M 6 HOH 503 1203 1052 HOH HOH A . M 6 HOH 504 1204 919 HOH HOH A . M 6 HOH 505 1205 1068 HOH HOH A . M 6 HOH 506 1206 662 HOH HOH A . M 6 HOH 507 1207 1267 HOH HOH A . M 6 HOH 508 1208 648 HOH HOH A . M 6 HOH 509 1209 969 HOH HOH A . M 6 HOH 510 1210 1246 HOH HOH A . M 6 HOH 511 1211 422 HOH HOH A . M 6 HOH 512 1212 1044 HOH HOH A . M 6 HOH 513 1213 1361 HOH HOH A . M 6 HOH 514 1214 928 HOH HOH A . M 6 HOH 515 1215 1349 HOH HOH A . M 6 HOH 516 1216 1104 HOH HOH A . M 6 HOH 517 1217 701 HOH HOH A . M 6 HOH 518 1218 964 HOH HOH A . M 6 HOH 519 1219 1185 HOH HOH A . M 6 HOH 520 1220 1043 HOH HOH A . M 6 HOH 521 1221 569 HOH HOH A . M 6 HOH 522 1222 1032 HOH HOH A . M 6 HOH 523 1223 639 HOH HOH A . M 6 HOH 524 1224 845 HOH HOH A . M 6 HOH 525 1225 960 HOH HOH A . M 6 HOH 526 1226 868 HOH HOH A . M 6 HOH 527 1227 549 HOH HOH A . M 6 HOH 528 1228 625 HOH HOH A . M 6 HOH 529 1229 1319 HOH HOH A . M 6 HOH 530 1230 1259 HOH HOH A . M 6 HOH 531 1231 770 HOH HOH A . M 6 HOH 532 1232 1325 HOH HOH A . M 6 HOH 533 1233 381 HOH HOH A . M 6 HOH 534 1234 465 HOH HOH A . M 6 HOH 535 1235 1154 HOH HOH A . M 6 HOH 536 1236 1283 HOH HOH A . M 6 HOH 537 1237 702 HOH HOH A . M 6 HOH 538 1238 641 HOH HOH A . M 6 HOH 539 1239 683 HOH HOH A . M 6 HOH 540 1240 271 HOH HOH A . M 6 HOH 541 1241 1094 HOH HOH A . M 6 HOH 542 1242 1289 HOH HOH A . M 6 HOH 543 1243 1266 HOH HOH A . M 6 HOH 544 1244 1144 HOH HOH A . M 6 HOH 545 1245 946 HOH HOH A . M 6 HOH 546 1246 1166 HOH HOH A . M 6 HOH 547 1247 1317 HOH HOH A . M 6 HOH 548 1248 961 HOH HOH A . M 6 HOH 549 1249 597 HOH HOH A . M 6 HOH 550 1250 1092 HOH HOH A . M 6 HOH 551 1251 557 HOH HOH A . M 6 HOH 552 1252 1177 HOH HOH A . M 6 HOH 553 1253 831 HOH HOH A . M 6 HOH 554 1254 1235 HOH HOH A . M 6 HOH 555 1255 1146 HOH HOH A . M 6 HOH 556 1256 972 HOH HOH A . M 6 HOH 557 1257 661 HOH HOH A . M 6 HOH 558 1258 653 HOH HOH A . M 6 HOH 559 1259 1172 HOH HOH A . M 6 HOH 560 1260 1175 HOH HOH A . M 6 HOH 561 1261 1278 HOH HOH A . M 6 HOH 562 1262 784 HOH HOH A . M 6 HOH 563 1263 990 HOH HOH A . M 6 HOH 564 1264 1008 HOH HOH A . M 6 HOH 565 1265 783 HOH HOH A . M 6 HOH 566 1266 525 HOH HOH A . M 6 HOH 567 1267 844 HOH HOH A . M 6 HOH 568 1268 612 HOH HOH A . M 6 HOH 569 1269 1148 HOH HOH A . M 6 HOH 570 1270 1023 HOH HOH A . M 6 HOH 571 1271 910 HOH HOH A . M 6 HOH 572 1272 949 HOH HOH A . M 6 HOH 573 1273 47 HOH HOH A . M 6 HOH 574 1274 1025 HOH HOH A . M 6 HOH 575 1275 997 HOH HOH A . M 6 HOH 576 1276 1112 HOH HOH A . M 6 HOH 577 1277 522 HOH HOH A . M 6 HOH 578 1278 613 HOH HOH A . M 6 HOH 579 1279 863 HOH HOH A . M 6 HOH 580 1280 606 HOH HOH A . M 6 HOH 581 1281 1187 HOH HOH A . M 6 HOH 582 1282 1242 HOH HOH A . M 6 HOH 583 1283 983 HOH HOH A . M 6 HOH 584 1284 210 HOH HOH A . M 6 HOH 585 1285 1157 HOH HOH A . M 6 HOH 586 1286 672 HOH HOH A . M 6 HOH 587 1287 956 HOH HOH A . M 6 HOH 588 1288 1116 HOH HOH A . M 6 HOH 589 1289 1165 HOH HOH A . M 6 HOH 590 1290 1168 HOH HOH A . M 6 HOH 591 1291 1101 HOH HOH A . M 6 HOH 592 1292 665 HOH HOH A . M 6 HOH 593 1293 1229 HOH HOH A . M 6 HOH 594 1294 1270 HOH HOH A . M 6 HOH 595 1295 1245 HOH HOH A . M 6 HOH 596 1296 1158 HOH HOH A . M 6 HOH 597 1297 1279 HOH HOH A . M 6 HOH 598 1298 602 HOH HOH A . M 6 HOH 599 1299 1108 HOH HOH A . M 6 HOH 600 1300 929 HOH HOH A . M 6 HOH 601 1301 554 HOH HOH A . M 6 HOH 602 1302 629 HOH HOH A . M 6 HOH 603 1303 1124 HOH HOH A . M 6 HOH 604 1304 930 HOH HOH A . M 6 HOH 605 1305 873 HOH HOH A . M 6 HOH 606 1306 1309 HOH HOH A . M 6 HOH 607 1307 273 HOH HOH A . M 6 HOH 608 1308 1111 HOH HOH A . M 6 HOH 609 1309 858 HOH HOH A . M 6 HOH 610 1310 1120 HOH HOH A . M 6 HOH 611 1311 1241 HOH HOH A . M 6 HOH 612 1312 1082 HOH HOH A . M 6 HOH 613 1313 516 HOH HOH A . M 6 HOH 614 1314 690 HOH HOH A . M 6 HOH 615 1315 642 HOH HOH A . M 6 HOH 616 1316 1010 HOH HOH A . M 6 HOH 617 1317 842 HOH HOH A . M 6 HOH 618 1318 1055 HOH HOH A . M 6 HOH 619 1319 1040 HOH HOH A . M 6 HOH 620 1320 999 HOH HOH A . M 6 HOH 621 1321 656 HOH HOH A . M 6 HOH 622 1322 799 HOH HOH A . M 6 HOH 623 1323 594 HOH HOH A . M 6 HOH 624 1324 1341 HOH HOH A . M 6 HOH 625 1325 373 HOH HOH A . M 6 HOH 626 1326 664 HOH HOH A . M 6 HOH 627 1327 833 HOH HOH A . M 6 HOH 628 1328 531 HOH HOH A . M 6 HOH 629 1329 787 HOH HOH A . M 6 HOH 630 1330 994 HOH HOH A . M 6 HOH 631 1331 872 HOH HOH A . M 6 HOH 632 1332 981 HOH HOH A . M 6 HOH 633 1333 1231 HOH HOH A . M 6 HOH 634 1334 1213 HOH HOH A . M 6 HOH 635 1335 330 HOH HOH A . M 6 HOH 636 1336 583 HOH HOH A . M 6 HOH 637 1337 1002 HOH HOH A . M 6 HOH 638 1338 646 HOH HOH A . M 6 HOH 639 1339 817 HOH HOH A . M 6 HOH 640 1340 1048 HOH HOH A . M 6 HOH 641 1341 666 HOH HOH A . M 6 HOH 642 1342 1221 HOH HOH A . M 6 HOH 643 1343 1099 HOH HOH A . M 6 HOH 644 1344 657 HOH HOH A . M 6 HOH 645 1345 1119 HOH HOH A . M 6 HOH 646 1346 1167 HOH HOH A . M 6 HOH 647 1347 1171 HOH HOH A . M 6 HOH 648 1348 1273 HOH HOH A . M 6 HOH 649 1349 1254 HOH HOH A . M 6 HOH 650 1350 497 HOH HOH A . M 6 HOH 651 1351 1014 HOH HOH A . M 6 HOH 652 1352 229 HOH HOH A . M 6 HOH 653 1353 1243 HOH HOH A . M 6 HOH 654 1354 313 HOH HOH A . M 6 HOH 655 1355 1195 HOH HOH A . M 6 HOH 656 1356 670 HOH HOH A . M 6 HOH 657 1357 1315 HOH HOH A . M 6 HOH 658 1358 1159 HOH HOH A . M 6 HOH 659 1359 1334 HOH HOH A . M 6 HOH 660 1360 444 HOH HOH A . M 6 HOH 661 1361 654 HOH HOH A . M 6 HOH 662 1362 926 HOH HOH A . M 6 HOH 663 1363 421 HOH HOH A . M 6 HOH 664 1364 1129 HOH HOH A . M 6 HOH 665 1365 1176 HOH HOH A . M 6 HOH 666 1366 1230 HOH HOH A . M 6 HOH 667 1367 1188 HOH HOH A . M 6 HOH 668 1368 767 HOH HOH A . M 6 HOH 669 1369 937 HOH HOH A . M 6 HOH 670 1370 1090 HOH HOH A . M 6 HOH 671 1371 1013 HOH HOH A . M 6 HOH 672 1372 804 HOH HOH A . M 6 HOH 673 1373 658 HOH HOH A . M 6 HOH 674 1374 892 HOH HOH A . M 6 HOH 675 1375 1103 HOH HOH A . M 6 HOH 676 1376 1037 HOH HOH A . M 6 HOH 677 1377 1303 HOH HOH A . M 6 HOH 678 1378 1316 HOH HOH A . M 6 HOH 679 1379 1339 HOH HOH A . M 6 HOH 680 1380 1296 HOH HOH A . M 6 HOH 681 1381 1162 HOH HOH A . M 6 HOH 682 1382 1161 HOH HOH A . N 6 HOH 1 1401 295 HOH HOH C . N 6 HOH 2 1402 737 HOH HOH C . N 6 HOH 3 1403 764 HOH HOH C . N 6 HOH 4 1404 1247 HOH HOH C . N 6 HOH 5 1405 1202 HOH HOH C . N 6 HOH 6 1406 411 HOH HOH C . N 6 HOH 7 1407 782 HOH HOH C . N 6 HOH 8 1408 198 HOH HOH C . N 6 HOH 9 1409 809 HOH HOH C . N 6 HOH 10 1410 1203 HOH HOH C . N 6 HOH 11 1411 1028 HOH HOH C . N 6 HOH 12 1412 1178 HOH HOH C . N 6 HOH 13 1413 315 HOH HOH C . N 6 HOH 14 1414 730 HOH HOH C . N 6 HOH 15 1415 1326 HOH HOH C . N 6 HOH 16 1416 13 HOH HOH C . N 6 HOH 17 1417 609 HOH HOH C . N 6 HOH 18 1418 898 HOH HOH C . N 6 HOH 19 1419 763 HOH HOH C . N 6 HOH 20 1420 1019 HOH HOH C . N 6 HOH 21 1421 1181 HOH HOH C . N 6 HOH 22 1422 376 HOH HOH C . N 6 HOH 23 1423 1249 HOH HOH C . N 6 HOH 24 1424 774 HOH HOH C . N 6 HOH 25 1425 480 HOH HOH C . N 6 HOH 26 1426 1208 HOH HOH C . N 6 HOH 27 1427 1346 HOH HOH C . N 6 HOH 28 1428 1333 HOH HOH C . N 6 HOH 29 1429 922 HOH HOH C . N 6 HOH 30 1430 830 HOH HOH C . O 6 HOH 1 701 705 HOH HOH B . O 6 HOH 2 702 686 HOH HOH B . O 6 HOH 3 703 988 HOH HOH B . O 6 HOH 4 704 709 HOH HOH B . O 6 HOH 5 705 1142 HOH HOH B . O 6 HOH 6 706 341 HOH HOH B . O 6 HOH 7 707 383 HOH HOH B . O 6 HOH 8 708 895 HOH HOH B . O 6 HOH 9 709 1299 HOH HOH B . O 6 HOH 10 710 278 HOH HOH B . O 6 HOH 11 711 593 HOH HOH B . O 6 HOH 12 712 469 HOH HOH B . O 6 HOH 13 713 1353 HOH HOH B . O 6 HOH 14 714 874 HOH HOH B . O 6 HOH 15 715 846 HOH HOH B . O 6 HOH 16 716 530 HOH HOH B . O 6 HOH 17 717 502 HOH HOH B . O 6 HOH 18 718 1286 HOH HOH B . O 6 HOH 19 719 588 HOH HOH B . O 6 HOH 20 720 486 HOH HOH B . O 6 HOH 21 721 512 HOH HOH B . O 6 HOH 22 722 1130 HOH HOH B . O 6 HOH 23 723 1330 HOH HOH B . O 6 HOH 24 724 1114 HOH HOH B . O 6 HOH 25 725 63 HOH HOH B . O 6 HOH 26 726 161 HOH HOH B . O 6 HOH 27 727 396 HOH HOH B . O 6 HOH 28 728 890 HOH HOH B . O 6 HOH 29 729 1136 HOH HOH B . O 6 HOH 30 730 1206 HOH HOH B . O 6 HOH 31 731 277 HOH HOH B . O 6 HOH 32 732 914 HOH HOH B . O 6 HOH 33 733 30 HOH HOH B . O 6 HOH 34 734 953 HOH HOH B . O 6 HOH 35 735 1294 HOH HOH B . O 6 HOH 36 736 539 HOH HOH B . O 6 HOH 37 737 989 HOH HOH B . O 6 HOH 38 738 265 HOH HOH B . O 6 HOH 39 739 320 HOH HOH B . O 6 HOH 40 740 750 HOH HOH B . O 6 HOH 41 741 993 HOH HOH B . O 6 HOH 42 742 1214 HOH HOH B . O 6 HOH 43 743 391 HOH HOH B . O 6 HOH 44 744 491 HOH HOH B . O 6 HOH 45 745 105 HOH HOH B . O 6 HOH 46 746 880 HOH HOH B . O 6 HOH 47 747 1058 HOH HOH B . O 6 HOH 48 748 619 HOH HOH B . O 6 HOH 49 749 119 HOH HOH B . O 6 HOH 50 750 847 HOH HOH B . O 6 HOH 51 751 998 HOH HOH B . O 6 HOH 52 752 791 HOH HOH B . O 6 HOH 53 753 739 HOH HOH B . O 6 HOH 54 754 287 HOH HOH B . O 6 HOH 55 755 481 HOH HOH B . O 6 HOH 56 756 1139 HOH HOH B . O 6 HOH 57 757 611 HOH HOH B . O 6 HOH 58 758 1134 HOH HOH B . O 6 HOH 59 759 586 HOH HOH B . O 6 HOH 60 760 364 HOH HOH B . O 6 HOH 61 761 854 HOH HOH B . O 6 HOH 62 762 259 HOH HOH B . O 6 HOH 63 763 145 HOH HOH B . O 6 HOH 64 764 107 HOH HOH B . O 6 HOH 65 765 545 HOH HOH B . O 6 HOH 66 766 436 HOH HOH B . O 6 HOH 67 767 142 HOH HOH B . O 6 HOH 68 768 162 HOH HOH B . O 6 HOH 69 769 707 HOH HOH B . O 6 HOH 70 770 1363 HOH HOH B . O 6 HOH 71 771 841 HOH HOH B . O 6 HOH 72 772 860 HOH HOH B . O 6 HOH 73 773 850 HOH HOH B . O 6 HOH 74 774 1233 HOH HOH B . O 6 HOH 75 775 197 HOH HOH B . O 6 HOH 76 776 917 HOH HOH B . O 6 HOH 77 777 375 HOH HOH B . O 6 HOH 78 778 521 HOH HOH B . O 6 HOH 79 779 585 HOH HOH B . O 6 HOH 80 780 580 HOH HOH B . O 6 HOH 81 781 251 HOH HOH B . O 6 HOH 82 782 360 HOH HOH B . O 6 HOH 83 783 165 HOH HOH B . O 6 HOH 84 784 1132 HOH HOH B . O 6 HOH 85 785 1 HOH HOH B . O 6 HOH 86 786 230 HOH HOH B . O 6 HOH 87 787 1292 HOH HOH B . O 6 HOH 88 788 1145 HOH HOH B . O 6 HOH 89 789 893 HOH HOH B . O 6 HOH 90 790 592 HOH HOH B . O 6 HOH 91 791 285 HOH HOH B . O 6 HOH 92 792 1070 HOH HOH B . O 6 HOH 93 793 180 HOH HOH B . O 6 HOH 94 794 274 HOH HOH B . O 6 HOH 95 795 538 HOH HOH B . O 6 HOH 96 796 954 HOH HOH B . O 6 HOH 97 797 572 HOH HOH B . O 6 HOH 98 798 1220 HOH HOH B . O 6 HOH 99 799 111 HOH HOH B . O 6 HOH 100 800 212 HOH HOH B . O 6 HOH 101 801 448 HOH HOH B . O 6 HOH 102 802 1304 HOH HOH B . O 6 HOH 103 803 344 HOH HOH B . O 6 HOH 104 804 558 HOH HOH B . O 6 HOH 105 805 132 HOH HOH B . O 6 HOH 106 806 316 HOH HOH B . O 6 HOH 107 807 1271 HOH HOH B . O 6 HOH 108 808 883 HOH HOH B . O 6 HOH 109 809 141 HOH HOH B . O 6 HOH 110 810 397 HOH HOH B . O 6 HOH 111 811 927 HOH HOH B . O 6 HOH 112 812 1140 HOH HOH B . O 6 HOH 113 813 1051 HOH HOH B . O 6 HOH 114 814 340 HOH HOH B . O 6 HOH 115 815 367 HOH HOH B . O 6 HOH 116 816 724 HOH HOH B . O 6 HOH 117 817 53 HOH HOH B . O 6 HOH 118 818 1095 HOH HOH B . O 6 HOH 119 819 152 HOH HOH B . O 6 HOH 120 820 237 HOH HOH B . O 6 HOH 121 821 568 HOH HOH B . O 6 HOH 122 822 420 HOH HOH B . O 6 HOH 123 823 86 HOH HOH B . O 6 HOH 124 824 126 HOH HOH B . O 6 HOH 125 825 546 HOH HOH B . O 6 HOH 126 826 294 HOH HOH B . O 6 HOH 127 827 178 HOH HOH B . O 6 HOH 128 828 325 HOH HOH B . O 6 HOH 129 829 58 HOH HOH B . O 6 HOH 130 830 89 HOH HOH B . O 6 HOH 131 831 147 HOH HOH B . O 6 HOH 132 832 543 HOH HOH B . O 6 HOH 133 833 93 HOH HOH B . O 6 HOH 134 834 1343 HOH HOH B . O 6 HOH 135 835 61 HOH HOH B . O 6 HOH 136 836 547 HOH HOH B . O 6 HOH 137 837 432 HOH HOH B . O 6 HOH 138 838 101 HOH HOH B . O 6 HOH 139 839 1059 HOH HOH B . O 6 HOH 140 840 84 HOH HOH B . O 6 HOH 141 841 76 HOH HOH B . O 6 HOH 142 842 515 HOH HOH B . O 6 HOH 143 843 428 HOH HOH B . O 6 HOH 144 844 798 HOH HOH B . O 6 HOH 145 845 189 HOH HOH B . O 6 HOH 146 846 768 HOH HOH B . O 6 HOH 147 847 802 HOH HOH B . O 6 HOH 148 848 713 HOH HOH B . O 6 HOH 149 849 125 HOH HOH B . O 6 HOH 150 850 416 HOH HOH B . O 6 HOH 151 851 524 HOH HOH B . O 6 HOH 152 852 319 HOH HOH B . O 6 HOH 153 853 116 HOH HOH B . O 6 HOH 154 854 68 HOH HOH B . O 6 HOH 155 855 712 HOH HOH B . O 6 HOH 156 856 529 HOH HOH B . O 6 HOH 157 857 97 HOH HOH B . O 6 HOH 158 858 225 HOH HOH B . O 6 HOH 159 859 204 HOH HOH B . O 6 HOH 160 860 589 HOH HOH B . O 6 HOH 161 861 861 HOH HOH B . O 6 HOH 162 862 317 HOH HOH B . O 6 HOH 163 863 500 HOH HOH B . O 6 HOH 164 864 24 HOH HOH B . O 6 HOH 165 865 741 HOH HOH B . O 6 HOH 166 866 192 HOH HOH B . O 6 HOH 167 867 148 HOH HOH B . O 6 HOH 168 868 837 HOH HOH B . O 6 HOH 169 869 136 HOH HOH B . O 6 HOH 170 870 403 HOH HOH B . O 6 HOH 171 871 909 HOH HOH B . O 6 HOH 172 872 224 HOH HOH B . O 6 HOH 173 873 128 HOH HOH B . O 6 HOH 174 874 301 HOH HOH B . O 6 HOH 175 875 630 HOH HOH B . O 6 HOH 176 876 677 HOH HOH B . O 6 HOH 177 877 628 HOH HOH B . O 6 HOH 178 878 760 HOH HOH B . O 6 HOH 179 879 626 HOH HOH B . O 6 HOH 180 880 578 HOH HOH B . O 6 HOH 181 881 179 HOH HOH B . O 6 HOH 182 882 130 HOH HOH B . O 6 HOH 183 883 290 HOH HOH B . O 6 HOH 184 884 20 HOH HOH B . O 6 HOH 185 885 261 HOH HOH B . O 6 HOH 186 886 96 HOH HOH B . O 6 HOH 187 887 1170 HOH HOH B . O 6 HOH 188 888 199 HOH HOH B . O 6 HOH 189 889 71 HOH HOH B . O 6 HOH 190 890 78 HOH HOH B . O 6 HOH 191 891 466 HOH HOH B . O 6 HOH 192 892 471 HOH HOH B . O 6 HOH 193 893 390 HOH HOH B . O 6 HOH 194 894 67 HOH HOH B . O 6 HOH 195 895 398 HOH HOH B . O 6 HOH 196 896 123 HOH HOH B . O 6 HOH 197 897 735 HOH HOH B . O 6 HOH 198 898 866 HOH HOH B . O 6 HOH 199 899 1237 HOH HOH B . O 6 HOH 200 900 1354 HOH HOH B . O 6 HOH 201 901 207 HOH HOH B . O 6 HOH 202 902 164 HOH HOH B . O 6 HOH 203 903 518 HOH HOH B . O 6 HOH 204 904 157 HOH HOH B . O 6 HOH 205 905 357 HOH HOH B . O 6 HOH 206 906 175 HOH HOH B . O 6 HOH 207 907 742 HOH HOH B . O 6 HOH 208 908 377 HOH HOH B . O 6 HOH 209 909 882 HOH HOH B . O 6 HOH 210 910 185 HOH HOH B . O 6 HOH 211 911 153 HOH HOH B . O 6 HOH 212 912 129 HOH HOH B . O 6 HOH 213 913 1004 HOH HOH B . O 6 HOH 214 914 121 HOH HOH B . O 6 HOH 215 915 191 HOH HOH B . O 6 HOH 216 916 419 HOH HOH B . O 6 HOH 217 917 23 HOH HOH B . O 6 HOH 218 918 406 HOH HOH B . O 6 HOH 219 919 1183 HOH HOH B . O 6 HOH 220 920 723 HOH HOH B . O 6 HOH 221 921 138 HOH HOH B . O 6 HOH 222 922 79 HOH HOH B . O 6 HOH 223 923 39 HOH HOH B . O 6 HOH 224 924 370 HOH HOH B . O 6 HOH 225 925 1281 HOH HOH B . O 6 HOH 226 926 950 HOH HOH B . O 6 HOH 227 927 94 HOH HOH B . O 6 HOH 228 928 1042 HOH HOH B . O 6 HOH 229 929 9 HOH HOH B . O 6 HOH 230 930 792 HOH HOH B . O 6 HOH 231 931 1224 HOH HOH B . O 6 HOH 232 932 260 HOH HOH B . O 6 HOH 233 933 443 HOH HOH B . O 6 HOH 234 934 896 HOH HOH B . O 6 HOH 235 935 856 HOH HOH B . O 6 HOH 236 936 958 HOH HOH B . O 6 HOH 237 937 293 HOH HOH B . O 6 HOH 238 938 887 HOH HOH B . O 6 HOH 239 939 725 HOH HOH B . O 6 HOH 240 940 753 HOH HOH B . O 6 HOH 241 941 32 HOH HOH B . O 6 HOH 242 942 535 HOH HOH B . O 6 HOH 243 943 31 HOH HOH B . O 6 HOH 244 944 266 HOH HOH B . O 6 HOH 245 945 1079 HOH HOH B . O 6 HOH 246 946 15 HOH HOH B . O 6 HOH 247 947 288 HOH HOH B . O 6 HOH 248 948 544 HOH HOH B . O 6 HOH 249 949 1244 HOH HOH B . O 6 HOH 250 950 10 HOH HOH B . O 6 HOH 251 951 206 HOH HOH B . O 6 HOH 252 952 242 HOH HOH B . O 6 HOH 253 953 35 HOH HOH B . O 6 HOH 254 954 1049 HOH HOH B . O 6 HOH 255 955 404 HOH HOH B . O 6 HOH 256 956 22 HOH HOH B . O 6 HOH 257 957 795 HOH HOH B . O 6 HOH 258 958 620 HOH HOH B . O 6 HOH 259 959 182 HOH HOH B . O 6 HOH 260 960 57 HOH HOH B . O 6 HOH 261 961 797 HOH HOH B . O 6 HOH 262 962 1156 HOH HOH B . O 6 HOH 263 963 305 HOH HOH B . O 6 HOH 264 964 1137 HOH HOH B . O 6 HOH 265 965 359 HOH HOH B . O 6 HOH 266 966 385 HOH HOH B . O 6 HOH 267 967 216 HOH HOH B . O 6 HOH 268 968 423 HOH HOH B . O 6 HOH 269 969 1201 HOH HOH B . O 6 HOH 270 970 156 HOH HOH B . O 6 HOH 271 971 408 HOH HOH B . O 6 HOH 272 972 940 HOH HOH B . O 6 HOH 273 973 6 HOH HOH B . O 6 HOH 274 974 644 HOH HOH B . O 6 HOH 275 975 805 HOH HOH B . O 6 HOH 276 976 324 HOH HOH B . O 6 HOH 277 977 1265 HOH HOH B . O 6 HOH 278 978 26 HOH HOH B . O 6 HOH 279 979 719 HOH HOH B . O 6 HOH 280 980 1322 HOH HOH B . O 6 HOH 281 981 433 HOH HOH B . O 6 HOH 282 982 550 HOH HOH B . O 6 HOH 283 983 652 HOH HOH B . O 6 HOH 284 984 766 HOH HOH B . O 6 HOH 285 985 33 HOH HOH B . O 6 HOH 286 986 256 HOH HOH B . O 6 HOH 287 987 29 HOH HOH B . O 6 HOH 288 988 777 HOH HOH B . O 6 HOH 289 989 577 HOH HOH B . O 6 HOH 290 990 249 HOH HOH B . O 6 HOH 291 991 818 HOH HOH B . O 6 HOH 292 992 660 HOH HOH B . O 6 HOH 293 993 470 HOH HOH B . O 6 HOH 294 994 779 HOH HOH B . O 6 HOH 295 995 99 HOH HOH B . O 6 HOH 296 996 181 HOH HOH B . O 6 HOH 297 997 338 HOH HOH B . O 6 HOH 298 998 537 HOH HOH B . O 6 HOH 299 999 498 HOH HOH B . O 6 HOH 300 1000 596 HOH HOH B . O 6 HOH 301 1001 369 HOH HOH B . O 6 HOH 302 1002 335 HOH HOH B . O 6 HOH 303 1003 337 HOH HOH B . O 6 HOH 304 1004 718 HOH HOH B . O 6 HOH 305 1005 824 HOH HOH B . O 6 HOH 306 1006 573 HOH HOH B . O 6 HOH 307 1007 786 HOH HOH B . O 6 HOH 308 1008 574 HOH HOH B . O 6 HOH 309 1009 51 HOH HOH B . O 6 HOH 310 1010 1204 HOH HOH B . O 6 HOH 311 1011 1359 HOH HOH B . O 6 HOH 312 1012 269 HOH HOH B . O 6 HOH 313 1013 172 HOH HOH B . O 6 HOH 314 1014 264 HOH HOH B . O 6 HOH 315 1015 60 HOH HOH B . O 6 HOH 316 1016 253 HOH HOH B . O 6 HOH 317 1017 1125 HOH HOH B . O 6 HOH 318 1018 168 HOH HOH B . O 6 HOH 319 1019 456 HOH HOH B . O 6 HOH 320 1020 488 HOH HOH B . O 6 HOH 321 1021 888 HOH HOH B . O 6 HOH 322 1022 1238 HOH HOH B . O 6 HOH 323 1023 643 HOH HOH B . O 6 HOH 324 1024 1081 HOH HOH B . O 6 HOH 325 1025 807 HOH HOH B . O 6 HOH 326 1026 1000 HOH HOH B . O 6 HOH 327 1027 551 HOH HOH B . O 6 HOH 328 1028 318 HOH HOH B . O 6 HOH 329 1029 991 HOH HOH B . O 6 HOH 330 1030 916 HOH HOH B . O 6 HOH 331 1031 624 HOH HOH B . O 6 HOH 332 1032 722 HOH HOH B . O 6 HOH 333 1033 64 HOH HOH B . O 6 HOH 334 1034 1200 HOH HOH B . O 6 HOH 335 1035 112 HOH HOH B . O 6 HOH 336 1036 1223 HOH HOH B . O 6 HOH 337 1037 1293 HOH HOH B . O 6 HOH 338 1038 354 HOH HOH B . O 6 HOH 339 1039 923 HOH HOH B . O 6 HOH 340 1040 40 HOH HOH B . O 6 HOH 341 1041 292 HOH HOH B . O 6 HOH 342 1042 118 HOH HOH B . O 6 HOH 343 1043 851 HOH HOH B . O 6 HOH 344 1044 3 HOH HOH B . O 6 HOH 345 1045 429 HOH HOH B . O 6 HOH 346 1046 610 HOH HOH B . O 6 HOH 347 1047 202 HOH HOH B . O 6 HOH 348 1048 936 HOH HOH B . O 6 HOH 349 1049 333 HOH HOH B . O 6 HOH 350 1050 430 HOH HOH B . O 6 HOH 351 1051 158 HOH HOH B . O 6 HOH 352 1052 328 HOH HOH B . O 6 HOH 353 1053 349 HOH HOH B . O 6 HOH 354 1054 331 HOH HOH B . O 6 HOH 355 1055 55 HOH HOH B . O 6 HOH 356 1056 366 HOH HOH B . O 6 HOH 357 1057 907 HOH HOH B . O 6 HOH 358 1058 5 HOH HOH B . O 6 HOH 359 1059 446 HOH HOH B . O 6 HOH 360 1060 622 HOH HOH B . O 6 HOH 361 1061 584 HOH HOH B . O 6 HOH 362 1062 48 HOH HOH B . O 6 HOH 363 1063 982 HOH HOH B . O 6 HOH 364 1064 884 HOH HOH B . O 6 HOH 365 1065 1075 HOH HOH B . O 6 HOH 366 1066 146 HOH HOH B . O 6 HOH 367 1067 920 HOH HOH B . O 6 HOH 368 1068 454 HOH HOH B . O 6 HOH 369 1069 716 HOH HOH B . O 6 HOH 370 1070 425 HOH HOH B . O 6 HOH 371 1071 503 HOH HOH B . O 6 HOH 372 1072 356 HOH HOH B . O 6 HOH 373 1073 308 HOH HOH B . O 6 HOH 374 1074 303 HOH HOH B . O 6 HOH 375 1075 394 HOH HOH B . O 6 HOH 376 1076 282 HOH HOH B . O 6 HOH 377 1077 1141 HOH HOH B . O 6 HOH 378 1078 1345 HOH HOH B . O 6 HOH 379 1079 289 HOH HOH B . O 6 HOH 380 1080 28 HOH HOH B . O 6 HOH 381 1081 1093 HOH HOH B . O 6 HOH 382 1082 140 HOH HOH B . O 6 HOH 383 1083 504 HOH HOH B . O 6 HOH 384 1084 1308 HOH HOH B . O 6 HOH 385 1085 857 HOH HOH B . O 6 HOH 386 1086 1026 HOH HOH B . O 6 HOH 387 1087 120 HOH HOH B . O 6 HOH 388 1088 296 HOH HOH B . O 6 HOH 389 1089 748 HOH HOH B . O 6 HOH 390 1090 1335 HOH HOH B . O 6 HOH 391 1091 483 HOH HOH B . O 6 HOH 392 1092 1084 HOH HOH B . O 6 HOH 393 1093 1350 HOH HOH B . O 6 HOH 394 1094 734 HOH HOH B . O 6 HOH 395 1095 87 HOH HOH B . O 6 HOH 396 1096 1015 HOH HOH B . O 6 HOH 397 1097 608 HOH HOH B . O 6 HOH 398 1098 1017 HOH HOH B . O 6 HOH 399 1099 649 HOH HOH B . O 6 HOH 400 1100 431 HOH HOH B . O 6 HOH 401 1101 426 HOH HOH B . O 6 HOH 402 1102 878 HOH HOH B . O 6 HOH 403 1103 222 HOH HOH B . O 6 HOH 404 1104 720 HOH HOH B . O 6 HOH 405 1105 1034 HOH HOH B . O 6 HOH 406 1106 952 HOH HOH B . O 6 HOH 407 1107 348 HOH HOH B . O 6 HOH 408 1108 759 HOH HOH B . O 6 HOH 409 1109 1209 HOH HOH B . O 6 HOH 410 1110 684 HOH HOH B . O 6 HOH 411 1111 1045 HOH HOH B . O 6 HOH 412 1112 1064 HOH HOH B . O 6 HOH 413 1113 673 HOH HOH B . O 6 HOH 414 1114 710 HOH HOH B . O 6 HOH 415 1115 669 HOH HOH B . O 6 HOH 416 1116 149 HOH HOH B . O 6 HOH 417 1117 1110 HOH HOH B . O 6 HOH 418 1118 402 HOH HOH B . O 6 HOH 419 1119 1205 HOH HOH B . O 6 HOH 420 1120 1207 HOH HOH B . O 6 HOH 421 1121 1147 HOH HOH B . O 6 HOH 422 1122 1331 HOH HOH B . O 6 HOH 423 1123 978 HOH HOH B . O 6 HOH 424 1124 1191 HOH HOH B . O 6 HOH 425 1125 915 HOH HOH B . O 6 HOH 426 1126 1255 HOH HOH B . O 6 HOH 427 1127 706 HOH HOH B . O 6 HOH 428 1128 1150 HOH HOH B . O 6 HOH 429 1129 1252 HOH HOH B . O 6 HOH 430 1130 1193 HOH HOH B . O 6 HOH 431 1131 875 HOH HOH B . O 6 HOH 432 1132 955 HOH HOH B . O 6 HOH 433 1133 281 HOH HOH B . O 6 HOH 434 1134 1272 HOH HOH B . O 6 HOH 435 1135 1268 HOH HOH B . O 6 HOH 436 1136 1210 HOH HOH B . O 6 HOH 437 1137 891 HOH HOH B . O 6 HOH 438 1138 974 HOH HOH B . O 6 HOH 439 1139 894 HOH HOH B . O 6 HOH 440 1140 1087 HOH HOH B . O 6 HOH 441 1141 1260 HOH HOH B . O 6 HOH 442 1142 908 HOH HOH B . O 6 HOH 443 1143 801 HOH HOH B . O 6 HOH 444 1144 581 HOH HOH B . O 6 HOH 445 1145 1282 HOH HOH B . O 6 HOH 446 1146 826 HOH HOH B . O 6 HOH 447 1147 1358 HOH HOH B . O 6 HOH 448 1148 342 HOH HOH B . O 6 HOH 449 1149 685 HOH HOH B . O 6 HOH 450 1150 877 HOH HOH B . O 6 HOH 451 1151 595 HOH HOH B . O 6 HOH 452 1152 1275 HOH HOH B . O 6 HOH 453 1153 647 HOH HOH B . O 6 HOH 454 1154 184 HOH HOH B . O 6 HOH 455 1155 601 HOH HOH B . O 6 HOH 456 1156 700 HOH HOH B . O 6 HOH 457 1157 70 HOH HOH B . O 6 HOH 458 1158 227 HOH HOH B . O 6 HOH 459 1159 280 HOH HOH B . O 6 HOH 460 1160 1046 HOH HOH B . O 6 HOH 461 1161 1073 HOH HOH B . O 6 HOH 462 1162 1190 HOH HOH B . O 6 HOH 463 1163 1264 HOH HOH B . O 6 HOH 464 1164 1003 HOH HOH B . O 6 HOH 465 1165 970 HOH HOH B . O 6 HOH 466 1166 1072 HOH HOH B . O 6 HOH 467 1167 510 HOH HOH B . O 6 HOH 468 1168 1301 HOH HOH B . O 6 HOH 469 1169 938 HOH HOH B . O 6 HOH 470 1170 1009 HOH HOH B . O 6 HOH 471 1171 691 HOH HOH B . O 6 HOH 472 1172 980 HOH HOH B . O 6 HOH 473 1173 605 HOH HOH B . O 6 HOH 474 1174 371 HOH HOH B . O 6 HOH 475 1175 738 HOH HOH B . O 6 HOH 476 1176 675 HOH HOH B . O 6 HOH 477 1177 788 HOH HOH B . O 6 HOH 478 1178 562 HOH HOH B . O 6 HOH 479 1179 1321 HOH HOH B . O 6 HOH 480 1180 793 HOH HOH B . O 6 HOH 481 1181 645 HOH HOH B . O 6 HOH 482 1182 1016 HOH HOH B . O 6 HOH 483 1183 1088 HOH HOH B . O 6 HOH 484 1184 127 HOH HOH B . O 6 HOH 485 1185 1123 HOH HOH B . O 6 HOH 486 1186 1030 HOH HOH B . O 6 HOH 487 1187 778 HOH HOH B . O 6 HOH 488 1188 640 HOH HOH B . O 6 HOH 489 1189 590 HOH HOH B . O 6 HOH 490 1190 967 HOH HOH B . O 6 HOH 491 1191 1065 HOH HOH B . O 6 HOH 492 1192 1127 HOH HOH B . O 6 HOH 493 1193 820 HOH HOH B . O 6 HOH 494 1194 931 HOH HOH B . O 6 HOH 495 1195 976 HOH HOH B . O 6 HOH 496 1196 852 HOH HOH B . O 6 HOH 497 1197 941 HOH HOH B . O 6 HOH 498 1198 905 HOH HOH B . O 6 HOH 499 1199 1328 HOH HOH B . O 6 HOH 500 1200 1194 HOH HOH B . O 6 HOH 501 1201 1324 HOH HOH B . O 6 HOH 502 1202 1047 HOH HOH B . O 6 HOH 503 1203 973 HOH HOH B . O 6 HOH 504 1204 1262 HOH HOH B . O 6 HOH 505 1205 962 HOH HOH B . O 6 HOH 506 1206 1323 HOH HOH B . O 6 HOH 507 1207 291 HOH HOH B . O 6 HOH 508 1208 681 HOH HOH B . O 6 HOH 509 1209 667 HOH HOH B . O 6 HOH 510 1210 1180 HOH HOH B . O 6 HOH 511 1211 1143 HOH HOH B . O 6 HOH 512 1212 697 HOH HOH B . O 6 HOH 513 1213 1122 HOH HOH B . O 6 HOH 514 1214 901 HOH HOH B . O 6 HOH 515 1215 615 HOH HOH B . O 6 HOH 516 1216 171 HOH HOH B . O 6 HOH 517 1217 996 HOH HOH B . O 6 HOH 518 1218 616 HOH HOH B . O 6 HOH 519 1219 881 HOH HOH B . O 6 HOH 520 1220 1196 HOH HOH B . O 6 HOH 521 1221 889 HOH HOH B . O 6 HOH 522 1222 775 HOH HOH B . O 6 HOH 523 1223 556 HOH HOH B . O 6 HOH 524 1224 1348 HOH HOH B . O 6 HOH 525 1225 1337 HOH HOH B . O 6 HOH 526 1226 1197 HOH HOH B . O 6 HOH 527 1227 776 HOH HOH B . O 6 HOH 528 1228 1329 HOH HOH B . O 6 HOH 529 1229 814 HOH HOH B . O 6 HOH 530 1230 638 HOH HOH B . O 6 HOH 531 1231 1184 HOH HOH B . O 6 HOH 532 1232 1313 HOH HOH B . O 6 HOH 533 1233 307 HOH HOH B . O 6 HOH 534 1234 992 HOH HOH B . O 6 HOH 535 1235 698 HOH HOH B . O 6 HOH 536 1236 1307 HOH HOH B . O 6 HOH 537 1237 987 HOH HOH B . O 6 HOH 538 1238 1039 HOH HOH B . O 6 HOH 539 1239 780 HOH HOH B . O 6 HOH 540 1240 948 HOH HOH B . O 6 HOH 541 1241 703 HOH HOH B . O 6 HOH 542 1242 1021 HOH HOH B . O 6 HOH 543 1243 944 HOH HOH B . O 6 HOH 544 1244 1256 HOH HOH B . O 6 HOH 545 1245 410 HOH HOH B . O 6 HOH 546 1246 821 HOH HOH B . O 6 HOH 547 1247 1063 HOH HOH B . O 6 HOH 548 1248 1121 HOH HOH B . O 6 HOH 549 1249 1199 HOH HOH B . O 6 HOH 550 1250 699 HOH HOH B . O 6 HOH 551 1251 1128 HOH HOH B . O 6 HOH 552 1252 823 HOH HOH B . O 6 HOH 553 1253 501 HOH HOH B . O 6 HOH 554 1254 1012 HOH HOH B . O 6 HOH 555 1255 819 HOH HOH B . O 6 HOH 556 1256 633 HOH HOH B . O 6 HOH 557 1257 1164 HOH HOH B . O 6 HOH 558 1258 663 HOH HOH B . O 6 HOH 559 1259 476 HOH HOH B . O 6 HOH 560 1260 1126 HOH HOH B . O 6 HOH 561 1261 1018 HOH HOH B . O 6 HOH 562 1262 1089 HOH HOH B . O 6 HOH 563 1263 1300 HOH HOH B . O 6 HOH 564 1264 704 HOH HOH B . O 6 HOH 565 1265 571 HOH HOH B . O 6 HOH 566 1266 1251 HOH HOH B . O 6 HOH 567 1267 679 HOH HOH B . O 6 HOH 568 1268 1020 HOH HOH B . O 6 HOH 569 1269 1098 HOH HOH B . O 6 HOH 570 1270 904 HOH HOH B . O 6 HOH 571 1271 1290 HOH HOH B . O 6 HOH 572 1272 925 HOH HOH B . O 6 HOH 573 1273 692 HOH HOH B . O 6 HOH 574 1274 449 HOH HOH B . O 6 HOH 575 1275 523 HOH HOH B . O 6 HOH 576 1276 659 HOH HOH B . O 6 HOH 577 1277 1305 HOH HOH B . O 6 HOH 578 1278 977 HOH HOH B . O 6 HOH 579 1279 859 HOH HOH B . O 6 HOH 580 1280 1007 HOH HOH B . O 6 HOH 581 1281 1277 HOH HOH B . O 6 HOH 582 1282 1295 HOH HOH B . O 6 HOH 583 1283 1033 HOH HOH B . O 6 HOH 584 1284 1102 HOH HOH B . O 6 HOH 585 1285 1216 HOH HOH B . O 6 HOH 586 1286 1189 HOH HOH B . O 6 HOH 587 1287 939 HOH HOH B . O 6 HOH 588 1288 1340 HOH HOH B . O 6 HOH 589 1289 1036 HOH HOH B . O 6 HOH 590 1290 682 HOH HOH B . O 6 HOH 591 1291 1234 HOH HOH B . O 6 HOH 592 1292 899 HOH HOH B . O 6 HOH 593 1293 771 HOH HOH B . O 6 HOH 594 1294 1253 HOH HOH B . O 6 HOH 595 1295 1174 HOH HOH B . O 6 HOH 596 1296 519 HOH HOH B . O 6 HOH 597 1297 552 HOH HOH B . O 6 HOH 598 1298 785 HOH HOH B . O 6 HOH 599 1299 1287 HOH HOH B . O 6 HOH 600 1300 1310 HOH HOH B . O 6 HOH 601 1301 1179 HOH HOH B . O 6 HOH 602 1302 1318 HOH HOH B . O 6 HOH 603 1303 167 HOH HOH B . O 6 HOH 604 1304 1056 HOH HOH B . O 6 HOH 605 1305 347 HOH HOH B . O 6 HOH 606 1306 1297 HOH HOH B . O 6 HOH 607 1307 527 HOH HOH B . O 6 HOH 608 1308 1211 HOH HOH B . O 6 HOH 609 1309 363 HOH HOH B . O 6 HOH 610 1310 971 HOH HOH B . O 6 HOH 611 1311 1091 HOH HOH B . O 6 HOH 612 1312 1105 HOH HOH B . O 6 HOH 613 1313 560 HOH HOH B . O 6 HOH 614 1314 839 HOH HOH B . O 6 HOH 615 1315 604 HOH HOH B . O 6 HOH 616 1316 540 HOH HOH B . O 6 HOH 617 1317 1152 HOH HOH B . O 6 HOH 618 1318 555 HOH HOH B . O 6 HOH 619 1319 1320 HOH HOH B . O 6 HOH 620 1320 1342 HOH HOH B . O 6 HOH 621 1321 1078 HOH HOH B . O 6 HOH 622 1322 1192 HOH HOH B . O 6 HOH 623 1323 1182 HOH HOH B . O 6 HOH 624 1324 1314 HOH HOH B . O 6 HOH 625 1325 1100 HOH HOH B . O 6 HOH 626 1326 1327 HOH HOH B . O 6 HOH 627 1327 1080 HOH HOH B . P 6 HOH 1 1401 1261 HOH HOH D . P 6 HOH 2 1402 906 HOH HOH D . P 6 HOH 3 1403 214 HOH HOH D . P 6 HOH 4 1404 1022 HOH HOH D . P 6 HOH 5 1405 1060 HOH HOH D . P 6 HOH 6 1406 455 HOH HOH D . P 6 HOH 7 1407 457 HOH HOH D . P 6 HOH 8 1408 740 HOH HOH D . P 6 HOH 9 1409 708 HOH HOH D . P 6 HOH 10 1410 829 HOH HOH D . P 6 HOH 11 1411 1135 HOH HOH D . P 6 HOH 12 1412 1302 HOH HOH D . P 6 HOH 13 1413 484 HOH HOH D . P 6 HOH 14 1414 1106 HOH HOH D . P 6 HOH 15 1415 399 HOH HOH D . P 6 HOH 16 1416 1054 HOH HOH D . P 6 HOH 17 1417 1067 HOH HOH D . P 6 HOH 18 1418 1285 HOH HOH D . P 6 HOH 19 1419 1284 HOH HOH D . P 6 HOH 20 1420 1219 HOH HOH D . P 6 HOH 21 1421 1306 HOH HOH D . P 6 HOH 22 1422 1107 HOH HOH D . # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA dimeric 2 2 author_and_software_defined_assembly PISA dimeric 2 3 software_defined_assembly PISA tetrameric 4 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,B,E,F,G,H,I,J,M,N 2 1 C,D,K,L,O,P 3 1 A,B,E,F,G,H,I,J,M,N 3 2 C,D,K,L,O,P # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 3220 ? 1 MORE -28 ? 1 'SSA (A^2)' 19320 ? 2 'ABSA (A^2)' 3190 ? 2 MORE -32 ? 2 'SSA (A^2)' 19500 ? 3 'ABSA (A^2)' 8910 ? 3 MORE -73 ? 3 'SSA (A^2)' 36310 ? # loop_ _pdbx_struct_oper_list.id _pdbx_struct_oper_list.type _pdbx_struct_oper_list.name _pdbx_struct_oper_list.symmetry_operation _pdbx_struct_oper_list.matrix[1][1] _pdbx_struct_oper_list.matrix[1][2] _pdbx_struct_oper_list.matrix[1][3] _pdbx_struct_oper_list.vector[1] _pdbx_struct_oper_list.matrix[2][1] _pdbx_struct_oper_list.matrix[2][2] _pdbx_struct_oper_list.matrix[2][3] _pdbx_struct_oper_list.vector[2] _pdbx_struct_oper_list.matrix[3][1] _pdbx_struct_oper_list.matrix[3][2] _pdbx_struct_oper_list.matrix[3][3] _pdbx_struct_oper_list.vector[3] 1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 2 'crystal symmetry operation' 5_565 y,-x+y+1,z+1/6 0.5000000000 0.8660254038 0.0000000000 -60.2800000000 -0.8660254038 0.5000000000 0.0000000000 104.4080226803 0.0000000000 0.0000000000 1.0000000000 23.6150000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2015-12-30 2 'Structure model' 1 1 2016-01-13 3 'Structure model' 1 2 2016-01-27 4 'Structure model' 1 3 2017-09-20 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Database references' 3 4 'Structure model' 'Author supporting evidence' 4 4 'Structure model' 'Database references' 5 4 'Structure model' 'Derived calculations' # loop_ _pdbx_audit_revision_category.ordinal _pdbx_audit_revision_category.revision_ordinal _pdbx_audit_revision_category.data_content_type _pdbx_audit_revision_category.category 1 4 'Structure model' citation 2 4 'Structure model' pdbx_audit_support 3 4 'Structure model' pdbx_struct_oper_list # loop_ _pdbx_audit_revision_item.ordinal _pdbx_audit_revision_item.revision_ordinal _pdbx_audit_revision_item.data_content_type _pdbx_audit_revision_item.item 1 4 'Structure model' '_citation.journal_id_CSD' 2 4 'Structure model' '_pdbx_audit_support.funding_organization' 3 4 'Structure model' '_pdbx_struct_oper_list.symmetry_operation' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? iMOSFLM ? ? ? . 1 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? . 2 ? phasing ? ? ? ? ? ? ? ? ? ? ? SHELX ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? . 4 ? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot ? ? ? . 5 ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.9_1692 6 ? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? 3.15 7 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 O B HOH 1093 ? ? O B HOH 1224 ? ? 1.72 2 1 O B HOH 1322 ? ? O B HOH 1324 ? ? 1.80 3 1 O A HOH 1188 ? ? O A HOH 1196 ? ? 1.81 4 1 O B HOH 1102 ? ? O B HOH 1236 ? ? 1.90 5 1 O B HOH 1017 ? ? O B HOH 1260 ? ? 1.90 6 1 O B HOH 1302 ? ? O B HOH 1317 ? ? 1.94 7 1 O A HOH 1290 ? ? O A HOH 1296 ? ? 1.94 8 1 O B HOH 710 ? ? O B HOH 1129 ? ? 1.95 9 1 O B HOH 1285 ? ? O B HOH 1308 ? ? 1.97 10 1 O B HOH 1138 ? ? O B HOH 1197 ? ? 1.98 11 1 O B HOH 1130 ? ? O B HOH 1132 ? ? 1.99 12 1 O A HOH 708 ? ? O A HOH 735 ? ? 2.00 13 1 O B HOH 1133 ? ? O B HOH 1199 ? ? 2.01 14 1 O A HOH 1197 ? ? O A HOH 1303 ? ? 2.01 15 1 O B HOH 1252 ? ? O B HOH 1314 ? ? 2.03 16 1 O B HOH 1124 ? ? O B HOH 1225 ? ? 2.04 17 1 O A HOH 715 ? ? O A HOH 991 ? ? 2.04 18 1 O B HOH 1288 ? ? O B HOH 1320 ? ? 2.06 19 1 O B HOH 1211 ? ? O B HOH 1285 ? ? 2.06 20 1 O B HOH 940 ? ? O B HOH 1072 ? ? 2.07 21 1 O A HOH 741 ? ? O A HOH 1203 ? ? 2.07 22 1 O B HOH 979 ? ? O B HOH 1004 ? ? 2.09 23 1 O B HOH 701 ? ? O B HOH 1127 ? ? 2.09 24 1 O A HOH 1232 ? ? O A HOH 1329 ? ? 2.10 25 1 OD2 C ASP 1320 ? ? O C HOH 1401 ? ? 2.10 26 1 O B HOH 1224 ? ? O B HOH 1235 ? ? 2.12 27 1 O A HOH 711 ? ? O A HOH 1198 ? ? 2.12 28 1 NH2 B ARG 163 ? ? O B HOH 701 ? ? 2.12 29 1 O A HOH 1268 ? ? O A HOH 1374 ? ? 2.15 30 1 O B HOH 971 ? ? O B HOH 1164 ? ? 2.15 31 1 O A HOH 798 ? ? O A HOH 1215 ? ? 2.15 32 1 O B HOH 712 ? ? O B HOH 788 ? ? 2.15 33 1 O A HOH 1173 ? ? O A HOH 1279 ? ? 2.15 34 1 O B HOH 935 ? ? O B HOH 961 ? ? 2.15 35 1 O A HOH 1003 ? ? O A HOH 1287 ? ? 2.16 36 1 O B HOH 1264 ? ? O B HOH 1267 ? ? 2.16 37 1 O B HOH 724 ? ? O B HOH 1228 ? ? 2.16 38 1 O A HOH 778 ? ? O A HOH 782 ? ? 2.16 39 1 OG A SER 187 ? ? O A HOH 701 ? ? 2.16 40 1 O A HOH 1023 ? ? O A HOH 1033 ? ? 2.17 41 1 O A HOH 878 ? ? O A HOH 1324 ? ? 2.19 42 1 O A HOH 1246 ? ? O A HOH 1281 ? ? 2.19 43 1 O A HOH 811 ? ? O A HOH 1300 ? ? 2.19 44 1 OG B SER 447 ? ? O B HOH 702 ? ? 2.19 # loop_ _pdbx_validate_symm_contact.id _pdbx_validate_symm_contact.PDB_model_num _pdbx_validate_symm_contact.auth_atom_id_1 _pdbx_validate_symm_contact.auth_asym_id_1 _pdbx_validate_symm_contact.auth_comp_id_1 _pdbx_validate_symm_contact.auth_seq_id_1 _pdbx_validate_symm_contact.PDB_ins_code_1 _pdbx_validate_symm_contact.label_alt_id_1 _pdbx_validate_symm_contact.site_symmetry_1 _pdbx_validate_symm_contact.auth_atom_id_2 _pdbx_validate_symm_contact.auth_asym_id_2 _pdbx_validate_symm_contact.auth_comp_id_2 _pdbx_validate_symm_contact.auth_seq_id_2 _pdbx_validate_symm_contact.PDB_ins_code_2 _pdbx_validate_symm_contact.label_alt_id_2 _pdbx_validate_symm_contact.site_symmetry_2 _pdbx_validate_symm_contact.dist 1 1 O A HOH 702 ? ? 1_555 O B HOH 1094 ? ? 3_575 1.90 2 1 O A HOH 1187 ? ? 1_555 O B HOH 1147 ? ? 5_565 2.03 3 1 O A HOH 1135 ? ? 1_555 O B HOH 796 ? ? 3_575 2.07 4 1 O A HOH 798 ? ? 1_555 O B HOH 1093 ? ? 5_565 2.08 5 1 O A HOH 992 ? ? 1_555 O B HOH 722 ? ? 5_565 2.15 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 SER A 184 ? ? 83.21 -5.95 2 1 LEU A 210 ? ? 63.14 176.60 3 1 CYS A 235 ? ? -100.85 42.18 4 1 PHE A 246 ? ? -100.42 -61.05 5 1 PRO A 257 ? ? -82.24 31.33 6 1 TYR A 261 ? ? -124.53 -136.75 7 1 ARG A 352 ? ? -148.19 21.84 8 1 LEU A 359 ? ? 71.17 -43.32 9 1 HIS A 387 ? ? -105.61 57.68 10 1 SER A 441 ? ? -86.99 -87.50 11 1 SER A 446 ? ? 71.44 -52.58 12 1 ASP A 464 ? ? -158.99 53.85 13 1 SER B 184 ? ? 79.75 -3.38 14 1 LEU B 210 ? ? 61.38 178.56 15 1 PHE B 246 ? ? -93.74 -62.92 16 1 PRO B 257 ? ? -80.63 32.77 17 1 TYR B 261 ? ? -126.82 -137.12 18 1 ARG B 352 ? ? -148.14 19.38 19 1 LEU B 359 ? ? 71.06 -39.10 20 1 HIS B 387 ? ? -106.46 55.66 21 1 SER B 441 ? ? -87.20 -87.75 22 1 SER B 446 ? ? 72.97 -53.12 23 1 ASP B 464 ? ? -163.27 54.27 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 GLY _pdbx_validate_peptide_omega.auth_asym_id_1 C _pdbx_validate_peptide_omega.auth_seq_id_1 1319 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 ASP _pdbx_validate_peptide_omega.auth_asym_id_2 C _pdbx_validate_peptide_omega.auth_seq_id_2 1320 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega 103.44 # loop_ _pdbx_distant_solvent_atoms.id _pdbx_distant_solvent_atoms.PDB_model_num _pdbx_distant_solvent_atoms.auth_atom_id _pdbx_distant_solvent_atoms.label_alt_id _pdbx_distant_solvent_atoms.auth_asym_id _pdbx_distant_solvent_atoms.auth_comp_id _pdbx_distant_solvent_atoms.auth_seq_id _pdbx_distant_solvent_atoms.PDB_ins_code _pdbx_distant_solvent_atoms.neighbor_macromolecule_distance _pdbx_distant_solvent_atoms.neighbor_ligand_distance 1 1 O ? A HOH 1377 ? 5.82 . 2 1 O ? A HOH 1378 ? 5.92 . 3 1 O ? A HOH 1379 ? 6.54 . 4 1 O ? A HOH 1380 ? 7.57 . 5 1 O ? A HOH 1381 ? 7.65 . 6 1 O ? A HOH 1382 ? 8.10 . 7 1 O ? B HOH 1324 ? 5.81 . 8 1 O ? B HOH 1325 ? 6.12 . 9 1 O ? B HOH 1326 ? 7.30 . 10 1 O ? B HOH 1327 ? 7.54 . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLY 53 ? A GLY 1 2 1 Y 1 A SER 54 ? A SER 2 3 1 Y 1 A ALA 55 ? A ALA 3 4 1 Y 1 A MET 56 ? A MET 4 5 1 Y 1 A GLY 57 ? A GLY 5 6 1 Y 1 A SER 58 ? A SER 6 7 1 Y 1 A SER 525 ? A SER 473 8 1 Y 1 A VAL 526 ? A VAL 474 9 1 Y 1 A ASP 527 ? A ASP 475 10 1 Y 1 A CYS 528 ? A CYS 476 11 1 Y 1 A GLY 529 ? A GLY 477 12 1 Y 1 A ALA 530 ? A ALA 478 13 1 Y 1 A HIS 531 ? A HIS 479 14 1 Y 1 A GLY 532 ? A GLY 480 15 1 Y 1 A THR 533 ? A THR 481 16 1 Y 1 A CYS 534 ? A CYS 482 17 1 Y 1 A ASP 535 ? A ASP 483 18 1 Y 1 A VAL 536 ? A VAL 484 19 1 Y 1 A ALA 537 ? A ALA 485 20 1 Y 1 A THR 538 ? A THR 486 21 1 Y 1 A GLY 539 ? A GLY 487 22 1 Y 1 A LYS 540 ? A LYS 488 23 1 Y 1 A CYS 541 ? A CYS 489 24 1 Y 1 A VAL 542 ? A VAL 490 25 1 Y 1 A CYS 543 ? A CYS 491 26 1 Y 1 A GLU 544 ? A GLU 492 27 1 Y 1 A PRO 545 ? A PRO 493 28 1 Y 1 A GLY 546 ? A GLY 494 29 1 Y 1 A PHE 547 ? A PHE 495 30 1 Y 1 A THR 548 ? A THR 496 31 1 Y 1 A GLY 549 ? A GLY 497 32 1 Y 1 A GLU 550 ? A GLU 498 33 1 Y 1 A ARG 551 ? A ARG 499 34 1 Y 1 A CYS 552 ? A CYS 500 35 1 Y 1 A ASP 553 ? A ASP 501 36 1 Y 1 A ALA 554 ? A ALA 502 37 1 Y 1 A ALA 555 ? A ALA 503 38 1 Y 1 A ALA 556 ? A ALA 504 39 1 Y 1 A LEU 557 ? A LEU 505 40 1 Y 1 A VAL 558 ? A VAL 506 41 1 Y 1 A PRO 559 ? A PRO 507 42 1 Y 1 A ARG 560 ? A ARG 508 43 1 Y 1 C GLY 1288 ? B GLY 1 44 1 Y 1 C SER 1289 ? B SER 2 45 1 Y 1 C ALA 1290 ? B ALA 3 46 1 Y 1 C SER 1291 ? B SER 4 47 1 Y 1 C GLN 1292 ? B GLN 5 48 1 Y 1 B GLY 53 ? C GLY 1 49 1 Y 1 B SER 54 ? C SER 2 50 1 Y 1 B ALA 55 ? C ALA 3 51 1 Y 1 B MET 56 ? C MET 4 52 1 Y 1 B GLY 57 ? C GLY 5 53 1 Y 1 B SER 58 ? C SER 6 54 1 Y 1 B SER 525 ? C SER 473 55 1 Y 1 B VAL 526 ? C VAL 474 56 1 Y 1 B ASP 527 ? C ASP 475 57 1 Y 1 B CYS 528 ? C CYS 476 58 1 Y 1 B GLY 529 ? C GLY 477 59 1 Y 1 B ALA 530 ? C ALA 478 60 1 Y 1 B HIS 531 ? C HIS 479 61 1 Y 1 B GLY 532 ? C GLY 480 62 1 Y 1 B THR 533 ? C THR 481 63 1 Y 1 B CYS 534 ? C CYS 482 64 1 Y 1 B ASP 535 ? C ASP 483 65 1 Y 1 B VAL 536 ? C VAL 484 66 1 Y 1 B ALA 537 ? C ALA 485 67 1 Y 1 B THR 538 ? C THR 486 68 1 Y 1 B GLY 539 ? C GLY 487 69 1 Y 1 B LYS 540 ? C LYS 488 70 1 Y 1 B CYS 541 ? C CYS 489 71 1 Y 1 B VAL 542 ? C VAL 490 72 1 Y 1 B CYS 543 ? C CYS 491 73 1 Y 1 B GLU 544 ? C GLU 492 74 1 Y 1 B PRO 545 ? C PRO 493 75 1 Y 1 B GLY 546 ? C GLY 494 76 1 Y 1 B PHE 547 ? C PHE 495 77 1 Y 1 B THR 548 ? C THR 496 78 1 Y 1 B GLY 549 ? C GLY 497 79 1 Y 1 B GLU 550 ? C GLU 498 80 1 Y 1 B ARG 551 ? C ARG 499 81 1 Y 1 B CYS 552 ? C CYS 500 82 1 Y 1 B ASP 553 ? C ASP 501 83 1 Y 1 B ALA 554 ? C ALA 502 84 1 Y 1 B ALA 555 ? C ALA 503 85 1 Y 1 B ALA 556 ? C ALA 504 86 1 Y 1 B LEU 557 ? C LEU 505 87 1 Y 1 B VAL 558 ? C VAL 506 88 1 Y 1 B PRO 559 ? C PRO 507 89 1 Y 1 B ARG 560 ? C ARG 508 90 1 Y 1 D GLY 1288 ? D GLY 1 91 1 Y 1 D SER 1289 ? D SER 2 92 1 Y 1 D ALA 1290 ? D ALA 3 93 1 Y 1 D SER 1291 ? D SER 4 94 1 Y 1 D GLN 1292 ? D GLN 5 95 1 Y 1 D ILE 1293 ? D ILE 6 # _pdbx_audit_support.funding_organization 'Canadian Institutes of Health Research' _pdbx_audit_support.country Canada _pdbx_audit_support.grant_number MOP82915 _pdbx_audit_support.ordinal 1 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 3 GLYCEROL GOL 4 'SULFATE ION' SO4 5 N-ACETYL-D-GLUCOSAMINE NAG 6 water HOH #