data_4XI5 # _entry.id 4XI5 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4XI5 WWPDB D_1000205700 # _pdbx_database_related.content_type unspecified _pdbx_database_related.db_id 4XHJ _pdbx_database_related.db_name PDB _pdbx_database_related.details . # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 4XI5 _pdbx_database_status.recvd_initial_deposition_date 2015-01-06 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # _audit_author.name 'Xing, Y.' _audit_author.pdbx_ordinal 1 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev Proc.Natl.Acad.Sci.USA _citation.journal_id_ASTM PNASA6 _citation.journal_id_CSD 0040 _citation.journal_id_ISSN 1091-6490 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 112 _citation.language ? _citation.page_first 6056 _citation.page_last 6061 _citation.title ;A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL. ; _citation.year 2015 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1073/pnas.1501176112 _citation.pdbx_database_id_PubMed 25918416 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Xing, Y.' 1 primary 'Oliver, S.L.' 2 primary 'Nguyen, T.' 3 primary 'Ciferri, C.' 4 primary 'Nandi, A.' 5 primary 'Hickman, J.' 6 primary 'Giovani, C.' 7 primary 'Yang, E.' 8 primary 'Palladino, G.' 9 primary 'Grose, C.' 10 primary 'Uematsu, Y.' 11 primary 'Lilja, A.E.' 12 primary 'Arvin, A.M.' 13 primary 'Carfi, A.' 14 # _cell.angle_alpha 90.00 _cell.angle_alpha_esd ? _cell.angle_beta 90.00 _cell.angle_beta_esd ? _cell.angle_gamma 90.00 _cell.angle_gamma_esd ? _cell.entry_id 4XI5 _cell.details ? _cell.formula_units_Z ? _cell.length_a 102.002 _cell.length_a_esd ? _cell.length_b 280.552 _cell.length_b_esd ? _cell.length_c 175.302 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 8 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 4XI5 _symmetry.cell_setting ? _symmetry.Int_Tables_number 20 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'C 2 2 21' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Envelope glycoprotein H' 92763.609 1 ? ? ? ? 2 polymer man 'Envelope glycoprotein L' 15197.178 1 ? ? ? ? 3 polymer man 'Fab-94 light chain' 23172.715 1 ? ? ? ? 4 polymer man 'Fab-94 heavy chain' 30198.682 1 ? ? ? ? 5 non-polymer syn N-ACETYL-D-GLUCOSAMINE 221.208 5 ? ? ? ? 6 non-polymer man BETA-D-MANNOSE 180.156 1 ? ? ? ? 7 non-polymer man ALPHA-D-MANNOSE 180.156 1 ? ? ? ? # loop_ _entity_name_com.entity_id _entity_name_com.name 1 'gH,Glycoprotein III,GPIII' 2 gL # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;MFALVLAVVILPLWTTANKSYVTPTPATRSIGHMSALLREYSDRNMSLKLEAFYPTGFDEELIKSLHWGNDRKHVFLVIV KVNPTTHEGDVGLVIFPKYLLSPYHFKAEHRAPFPAGRFGFLSHPVTPDVSFFDSSFAPYLTTQHLVAFTTFPPNPLVWH LERAETAATAERPFGVSLLPARPTVPKNTILEHKAHFATWDALARHTFFSAEAIITNSTLRIHVPLFGSVWPIRYWATGS VLLTSDSGRVEVNIGVGFMSSLISLSSGLPIELIVVPHTVKLNAVTSDTTWFQLNPPGPDPGPSYRVYLLGRGLDMNFSK HATVDICAYPEESLDYRYHLSMAHTEALRMTTKADQHDINEESYYHIAARIATSIFALSEMGRTTEYFLLDEIVDVQYQL KFLNYILMRIGAGAHPNTISGTSDLIFADPSQLHDELSLLFGQVKPANVDYFISYDEARDQLKTAYALSRGQDHVNALSL ARRVIMSIYKGLLVKQNLNATERQALFFASMILLNFREGLENSSRVLDGRTTLLLMTSMCTAAHATQAALNIQEGLAYLN PSKHMFTIPNVYSPCMGSLRTDLTEEIHVMNLLSAIPTRPGLNEVLHTQLDESEIFDAAFKTMMIFTTWTAKDLHILHTH VPEVFTCQDAAARNGEYVLILPAVQGHSYVITRNKPQRGLVYSLADVDVYNPISVVYLSKDTCVSEHGVIETVALPHPDN LKECLYCGSVFLRYLTTGAIMDIIIIDSKDTERQLAAMGNSTIPPFNPDMHGDDSKAVLLFPNGTVVTLLGFERRGSENL YFQGSWSHPQFEKGGGSGGGSGGGSWSHPQFEK ; ;MFALVLAVVILPLWTTANKSYVTPTPATRSIGHMSALLREYSDRNMSLKLEAFYPTGFDEELIKSLHWGNDRKHVFLVIV KVNPTTHEGDVGLVIFPKYLLSPYHFKAEHRAPFPAGRFGFLSHPVTPDVSFFDSSFAPYLTTQHLVAFTTFPPNPLVWH LERAETAATAERPFGVSLLPARPTVPKNTILEHKAHFATWDALARHTFFSAEAIITNSTLRIHVPLFGSVWPIRYWATGS VLLTSDSGRVEVNIGVGFMSSLISLSSGLPIELIVVPHTVKLNAVTSDTTWFQLNPPGPDPGPSYRVYLLGRGLDMNFSK HATVDICAYPEESLDYRYHLSMAHTEALRMTTKADQHDINEESYYHIAARIATSIFALSEMGRTTEYFLLDEIVDVQYQL KFLNYILMRIGAGAHPNTISGTSDLIFADPSQLHDELSLLFGQVKPANVDYFISYDEARDQLKTAYALSRGQDHVNALSL ARRVIMSIYKGLLVKQNLNATERQALFFASMILLNFREGLENSSRVLDGRTTLLLMTSMCTAAHATQAALNIQEGLAYLN PSKHMFTIPNVYSPCMGSLRTDLTEEIHVMNLLSAIPTRPGLNEVLHTQLDESEIFDAAFKTMMIFTTWTAKDLHILHTH VPEVFTCQDAAARNGEYVLILPAVQGHSYVITRNKPQRGLVYSLADVDVYNPISVVYLSKDTCVSEHGVIETVALPHPDN LKECLYCGSVFLRYLTTGAIMDIIIIDSKDTERQLAAMGNSTIPPFNPDMHGDDSKAVLLFPNGTVVTLLGFERRGSENL YFQGSWSHPQFEKGGGSGGGSGGGSWSHPQFEK ; A ? 2 'polypeptide(L)' no no ;LHLQDDTPLFFGAKPLSDVSLIITEPCVSSVYEAWDYAAPPVSNLSEALSGIVVKTKCPVPEVILWFKDKQMAYWTNPYV TLKGLTQSVGEEHKSGDIRDALLDALSGVWVDSTPSSTNIPENGCVWGADRLFQRVCQ ; ;LHLQDDTPLFFGAKPLSDVSLIITEPCVSSVYEAWDYAAPPVSNLSEALSGIVVKTKCPVPEVILWFKDKQMAYWTNPYV TLKGLTQSVGEEHKSGDIRDALLDALSGVWVDSTPSSTNIPENGCVWGADRLFQRVCQ ; B ? 3 'polypeptide(L)' no no ;DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQP EDFATYYCQQANNFPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC ; ;DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQP EDFATYYCQQANNFPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC ; C ? 4 'polypeptide(L)' no no ;MEFGLSWVFLVAILEGVHCEVQLVESGGGVVQPGRSLRLSCGASGFTFNTYAMHWVRQAPGKGVEWVAVVSDGGGNRYYA ASVKGRFTISRDNSKNTLFLQLNTLRPEDTAVYYCARSRGNHYYYGMDVWGRGTTVTVSSASTKGPSVFPLAPSSKSTSG GTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP KSCDKGSENLYFQGSWSHPQFEKGGGSGGGSGGGSWSHPQFEK ; ;MEFGLSWVFLVAILEGVHCEVQLVESGGGVVQPGRSLRLSCGASGFTFNTYAMHWVRQAPGKGVEWVAVVSDGGGNRYYA ASVKGRFTISRDNSKNTLFLQLNTLRPEDTAVYYCARSRGNHYYYGMDVWGRGTTVTVSSASTKGPSVFPLAPSSKSTSG GTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP KSCDKGSENLYFQGSWSHPQFEKGGGSGGGSGGGSWSHPQFEK ; D ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 MET n 1 2 PHE n 1 3 ALA n 1 4 LEU n 1 5 VAL n 1 6 LEU n 1 7 ALA n 1 8 VAL n 1 9 VAL n 1 10 ILE n 1 11 LEU n 1 12 PRO n 1 13 LEU n 1 14 TRP n 1 15 THR n 1 16 THR n 1 17 ALA n 1 18 ASN n 1 19 LYS n 1 20 SER n 1 21 TYR n 1 22 VAL n 1 23 THR n 1 24 PRO n 1 25 THR n 1 26 PRO n 1 27 ALA n 1 28 THR n 1 29 ARG n 1 30 SER n 1 31 ILE n 1 32 GLY n 1 33 HIS n 1 34 MET n 1 35 SER n 1 36 ALA n 1 37 LEU n 1 38 LEU n 1 39 ARG n 1 40 GLU n 1 41 TYR n 1 42 SER n 1 43 ASP n 1 44 ARG n 1 45 ASN n 1 46 MET n 1 47 SER n 1 48 LEU n 1 49 LYS n 1 50 LEU n 1 51 GLU n 1 52 ALA n 1 53 PHE n 1 54 TYR n 1 55 PRO n 1 56 THR n 1 57 GLY n 1 58 PHE n 1 59 ASP n 1 60 GLU n 1 61 GLU n 1 62 LEU n 1 63 ILE n 1 64 LYS n 1 65 SER n 1 66 LEU n 1 67 HIS n 1 68 TRP n 1 69 GLY n 1 70 ASN n 1 71 ASP n 1 72 ARG n 1 73 LYS n 1 74 HIS n 1 75 VAL n 1 76 PHE n 1 77 LEU n 1 78 VAL n 1 79 ILE n 1 80 VAL n 1 81 LYS n 1 82 VAL n 1 83 ASN n 1 84 PRO n 1 85 THR n 1 86 THR n 1 87 HIS n 1 88 GLU n 1 89 GLY n 1 90 ASP n 1 91 VAL n 1 92 GLY n 1 93 LEU n 1 94 VAL n 1 95 ILE n 1 96 PHE n 1 97 PRO n 1 98 LYS n 1 99 TYR n 1 100 LEU n 1 101 LEU n 1 102 SER n 1 103 PRO n 1 104 TYR n 1 105 HIS n 1 106 PHE n 1 107 LYS n 1 108 ALA n 1 109 GLU n 1 110 HIS n 1 111 ARG n 1 112 ALA n 1 113 PRO n 1 114 PHE n 1 115 PRO n 1 116 ALA n 1 117 GLY n 1 118 ARG n 1 119 PHE n 1 120 GLY n 1 121 PHE n 1 122 LEU n 1 123 SER n 1 124 HIS n 1 125 PRO n 1 126 VAL n 1 127 THR n 1 128 PRO n 1 129 ASP n 1 130 VAL n 1 131 SER n 1 132 PHE n 1 133 PHE n 1 134 ASP n 1 135 SER n 1 136 SER n 1 137 PHE n 1 138 ALA n 1 139 PRO n 1 140 TYR n 1 141 LEU n 1 142 THR n 1 143 THR n 1 144 GLN n 1 145 HIS n 1 146 LEU n 1 147 VAL n 1 148 ALA n 1 149 PHE n 1 150 THR n 1 151 THR n 1 152 PHE n 1 153 PRO n 1 154 PRO n 1 155 ASN n 1 156 PRO n 1 157 LEU n 1 158 VAL n 1 159 TRP n 1 160 HIS n 1 161 LEU n 1 162 GLU n 1 163 ARG n 1 164 ALA n 1 165 GLU n 1 166 THR n 1 167 ALA n 1 168 ALA n 1 169 THR n 1 170 ALA n 1 171 GLU n 1 172 ARG n 1 173 PRO n 1 174 PHE n 1 175 GLY n 1 176 VAL n 1 177 SER n 1 178 LEU n 1 179 LEU n 1 180 PRO n 1 181 ALA n 1 182 ARG n 1 183 PRO n 1 184 THR n 1 185 VAL n 1 186 PRO n 1 187 LYS n 1 188 ASN n 1 189 THR n 1 190 ILE n 1 191 LEU n 1 192 GLU n 1 193 HIS n 1 194 LYS n 1 195 ALA n 1 196 HIS n 1 197 PHE n 1 198 ALA n 1 199 THR n 1 200 TRP n 1 201 ASP n 1 202 ALA n 1 203 LEU n 1 204 ALA n 1 205 ARG n 1 206 HIS n 1 207 THR n 1 208 PHE n 1 209 PHE n 1 210 SER n 1 211 ALA n 1 212 GLU n 1 213 ALA n 1 214 ILE n 1 215 ILE n 1 216 THR n 1 217 ASN n 1 218 SER n 1 219 THR n 1 220 LEU n 1 221 ARG n 1 222 ILE n 1 223 HIS n 1 224 VAL n 1 225 PRO n 1 226 LEU n 1 227 PHE n 1 228 GLY n 1 229 SER n 1 230 VAL n 1 231 TRP n 1 232 PRO n 1 233 ILE n 1 234 ARG n 1 235 TYR n 1 236 TRP n 1 237 ALA n 1 238 THR n 1 239 GLY n 1 240 SER n 1 241 VAL n 1 242 LEU n 1 243 LEU n 1 244 THR n 1 245 SER n 1 246 ASP n 1 247 SER n 1 248 GLY n 1 249 ARG n 1 250 VAL n 1 251 GLU n 1 252 VAL n 1 253 ASN n 1 254 ILE n 1 255 GLY n 1 256 VAL n 1 257 GLY n 1 258 PHE n 1 259 MET n 1 260 SER n 1 261 SER n 1 262 LEU n 1 263 ILE n 1 264 SER n 1 265 LEU n 1 266 SER n 1 267 SER n 1 268 GLY n 1 269 LEU n 1 270 PRO n 1 271 ILE n 1 272 GLU n 1 273 LEU n 1 274 ILE n 1 275 VAL n 1 276 VAL n 1 277 PRO n 1 278 HIS n 1 279 THR n 1 280 VAL n 1 281 LYS n 1 282 LEU n 1 283 ASN n 1 284 ALA n 1 285 VAL n 1 286 THR n 1 287 SER n 1 288 ASP n 1 289 THR n 1 290 THR n 1 291 TRP n 1 292 PHE n 1 293 GLN n 1 294 LEU n 1 295 ASN n 1 296 PRO n 1 297 PRO n 1 298 GLY n 1 299 PRO n 1 300 ASP n 1 301 PRO n 1 302 GLY n 1 303 PRO n 1 304 SER n 1 305 TYR n 1 306 ARG n 1 307 VAL n 1 308 TYR n 1 309 LEU n 1 310 LEU n 1 311 GLY n 1 312 ARG n 1 313 GLY n 1 314 LEU n 1 315 ASP n 1 316 MET n 1 317 ASN n 1 318 PHE n 1 319 SER n 1 320 LYS n 1 321 HIS n 1 322 ALA n 1 323 THR n 1 324 VAL n 1 325 ASP n 1 326 ILE n 1 327 CYS n 1 328 ALA n 1 329 TYR n 1 330 PRO n 1 331 GLU n 1 332 GLU n 1 333 SER n 1 334 LEU n 1 335 ASP n 1 336 TYR n 1 337 ARG n 1 338 TYR n 1 339 HIS n 1 340 LEU n 1 341 SER n 1 342 MET n 1 343 ALA n 1 344 HIS n 1 345 THR n 1 346 GLU n 1 347 ALA n 1 348 LEU n 1 349 ARG n 1 350 MET n 1 351 THR n 1 352 THR n 1 353 LYS n 1 354 ALA n 1 355 ASP n 1 356 GLN n 1 357 HIS n 1 358 ASP n 1 359 ILE n 1 360 ASN n 1 361 GLU n 1 362 GLU n 1 363 SER n 1 364 TYR n 1 365 TYR n 1 366 HIS n 1 367 ILE n 1 368 ALA n 1 369 ALA n 1 370 ARG n 1 371 ILE n 1 372 ALA n 1 373 THR n 1 374 SER n 1 375 ILE n 1 376 PHE n 1 377 ALA n 1 378 LEU n 1 379 SER n 1 380 GLU n 1 381 MET n 1 382 GLY n 1 383 ARG n 1 384 THR n 1 385 THR n 1 386 GLU n 1 387 TYR n 1 388 PHE n 1 389 LEU n 1 390 LEU n 1 391 ASP n 1 392 GLU n 1 393 ILE n 1 394 VAL n 1 395 ASP n 1 396 VAL n 1 397 GLN n 1 398 TYR n 1 399 GLN n 1 400 LEU n 1 401 LYS n 1 402 PHE n 1 403 LEU n 1 404 ASN n 1 405 TYR n 1 406 ILE n 1 407 LEU n 1 408 MET n 1 409 ARG n 1 410 ILE n 1 411 GLY n 1 412 ALA n 1 413 GLY n 1 414 ALA n 1 415 HIS n 1 416 PRO n 1 417 ASN n 1 418 THR n 1 419 ILE n 1 420 SER n 1 421 GLY n 1 422 THR n 1 423 SER n 1 424 ASP n 1 425 LEU n 1 426 ILE n 1 427 PHE n 1 428 ALA n 1 429 ASP n 1 430 PRO n 1 431 SER n 1 432 GLN n 1 433 LEU n 1 434 HIS n 1 435 ASP n 1 436 GLU n 1 437 LEU n 1 438 SER n 1 439 LEU n 1 440 LEU n 1 441 PHE n 1 442 GLY n 1 443 GLN n 1 444 VAL n 1 445 LYS n 1 446 PRO n 1 447 ALA n 1 448 ASN n 1 449 VAL n 1 450 ASP n 1 451 TYR n 1 452 PHE n 1 453 ILE n 1 454 SER n 1 455 TYR n 1 456 ASP n 1 457 GLU n 1 458 ALA n 1 459 ARG n 1 460 ASP n 1 461 GLN n 1 462 LEU n 1 463 LYS n 1 464 THR n 1 465 ALA n 1 466 TYR n 1 467 ALA n 1 468 LEU n 1 469 SER n 1 470 ARG n 1 471 GLY n 1 472 GLN n 1 473 ASP n 1 474 HIS n 1 475 VAL n 1 476 ASN n 1 477 ALA n 1 478 LEU n 1 479 SER n 1 480 LEU n 1 481 ALA n 1 482 ARG n 1 483 ARG n 1 484 VAL n 1 485 ILE n 1 486 MET n 1 487 SER n 1 488 ILE n 1 489 TYR n 1 490 LYS n 1 491 GLY n 1 492 LEU n 1 493 LEU n 1 494 VAL n 1 495 LYS n 1 496 GLN n 1 497 ASN n 1 498 LEU n 1 499 ASN n 1 500 ALA n 1 501 THR n 1 502 GLU n 1 503 ARG n 1 504 GLN n 1 505 ALA n 1 506 LEU n 1 507 PHE n 1 508 PHE n 1 509 ALA n 1 510 SER n 1 511 MET n 1 512 ILE n 1 513 LEU n 1 514 LEU n 1 515 ASN n 1 516 PHE n 1 517 ARG n 1 518 GLU n 1 519 GLY n 1 520 LEU n 1 521 GLU n 1 522 ASN n 1 523 SER n 1 524 SER n 1 525 ARG n 1 526 VAL n 1 527 LEU n 1 528 ASP n 1 529 GLY n 1 530 ARG n 1 531 THR n 1 532 THR n 1 533 LEU n 1 534 LEU n 1 535 LEU n 1 536 MET n 1 537 THR n 1 538 SER n 1 539 MET n 1 540 CYS n 1 541 THR n 1 542 ALA n 1 543 ALA n 1 544 HIS n 1 545 ALA n 1 546 THR n 1 547 GLN n 1 548 ALA n 1 549 ALA n 1 550 LEU n 1 551 ASN n 1 552 ILE n 1 553 GLN n 1 554 GLU n 1 555 GLY n 1 556 LEU n 1 557 ALA n 1 558 TYR n 1 559 LEU n 1 560 ASN n 1 561 PRO n 1 562 SER n 1 563 LYS n 1 564 HIS n 1 565 MET n 1 566 PHE n 1 567 THR n 1 568 ILE n 1 569 PRO n 1 570 ASN n 1 571 VAL n 1 572 TYR n 1 573 SER n 1 574 PRO n 1 575 CYS n 1 576 MET n 1 577 GLY n 1 578 SER n 1 579 LEU n 1 580 ARG n 1 581 THR n 1 582 ASP n 1 583 LEU n 1 584 THR n 1 585 GLU n 1 586 GLU n 1 587 ILE n 1 588 HIS n 1 589 VAL n 1 590 MET n 1 591 ASN n 1 592 LEU n 1 593 LEU n 1 594 SER n 1 595 ALA n 1 596 ILE n 1 597 PRO n 1 598 THR n 1 599 ARG n 1 600 PRO n 1 601 GLY n 1 602 LEU n 1 603 ASN n 1 604 GLU n 1 605 VAL n 1 606 LEU n 1 607 HIS n 1 608 THR n 1 609 GLN n 1 610 LEU n 1 611 ASP n 1 612 GLU n 1 613 SER n 1 614 GLU n 1 615 ILE n 1 616 PHE n 1 617 ASP n 1 618 ALA n 1 619 ALA n 1 620 PHE n 1 621 LYS n 1 622 THR n 1 623 MET n 1 624 MET n 1 625 ILE n 1 626 PHE n 1 627 THR n 1 628 THR n 1 629 TRP n 1 630 THR n 1 631 ALA n 1 632 LYS n 1 633 ASP n 1 634 LEU n 1 635 HIS n 1 636 ILE n 1 637 LEU n 1 638 HIS n 1 639 THR n 1 640 HIS n 1 641 VAL n 1 642 PRO n 1 643 GLU n 1 644 VAL n 1 645 PHE n 1 646 THR n 1 647 CYS n 1 648 GLN n 1 649 ASP n 1 650 ALA n 1 651 ALA n 1 652 ALA n 1 653 ARG n 1 654 ASN n 1 655 GLY n 1 656 GLU n 1 657 TYR n 1 658 VAL n 1 659 LEU n 1 660 ILE n 1 661 LEU n 1 662 PRO n 1 663 ALA n 1 664 VAL n 1 665 GLN n 1 666 GLY n 1 667 HIS n 1 668 SER n 1 669 TYR n 1 670 VAL n 1 671 ILE n 1 672 THR n 1 673 ARG n 1 674 ASN n 1 675 LYS n 1 676 PRO n 1 677 GLN n 1 678 ARG n 1 679 GLY n 1 680 LEU n 1 681 VAL n 1 682 TYR n 1 683 SER n 1 684 LEU n 1 685 ALA n 1 686 ASP n 1 687 VAL n 1 688 ASP n 1 689 VAL n 1 690 TYR n 1 691 ASN n 1 692 PRO n 1 693 ILE n 1 694 SER n 1 695 VAL n 1 696 VAL n 1 697 TYR n 1 698 LEU n 1 699 SER n 1 700 LYS n 1 701 ASP n 1 702 THR n 1 703 CYS n 1 704 VAL n 1 705 SER n 1 706 GLU n 1 707 HIS n 1 708 GLY n 1 709 VAL n 1 710 ILE n 1 711 GLU n 1 712 THR n 1 713 VAL n 1 714 ALA n 1 715 LEU n 1 716 PRO n 1 717 HIS n 1 718 PRO n 1 719 ASP n 1 720 ASN n 1 721 LEU n 1 722 LYS n 1 723 GLU n 1 724 CYS n 1 725 LEU n 1 726 TYR n 1 727 CYS n 1 728 GLY n 1 729 SER n 1 730 VAL n 1 731 PHE n 1 732 LEU n 1 733 ARG n 1 734 TYR n 1 735 LEU n 1 736 THR n 1 737 THR n 1 738 GLY n 1 739 ALA n 1 740 ILE n 1 741 MET n 1 742 ASP n 1 743 ILE n 1 744 ILE n 1 745 ILE n 1 746 ILE n 1 747 ASP n 1 748 SER n 1 749 LYS n 1 750 ASP n 1 751 THR n 1 752 GLU n 1 753 ARG n 1 754 GLN n 1 755 LEU n 1 756 ALA n 1 757 ALA n 1 758 MET n 1 759 GLY n 1 760 ASN n 1 761 SER n 1 762 THR n 1 763 ILE n 1 764 PRO n 1 765 PRO n 1 766 PHE n 1 767 ASN n 1 768 PRO n 1 769 ASP n 1 770 MET n 1 771 HIS n 1 772 GLY n 1 773 ASP n 1 774 ASP n 1 775 SER n 1 776 LYS n 1 777 ALA n 1 778 VAL n 1 779 LEU n 1 780 LEU n 1 781 PHE n 1 782 PRO n 1 783 ASN n 1 784 GLY n 1 785 THR n 1 786 VAL n 1 787 VAL n 1 788 THR n 1 789 LEU n 1 790 LEU n 1 791 GLY n 1 792 PHE n 1 793 GLU n 1 794 ARG n 1 795 ARG n 1 796 GLY n 1 797 SER n 1 798 GLU n 1 799 ASN n 1 800 LEU n 1 801 TYR n 1 802 PHE n 1 803 GLN n 1 804 GLY n 1 805 SER n 1 806 TRP n 1 807 SER n 1 808 HIS n 1 809 PRO n 1 810 GLN n 1 811 PHE n 1 812 GLU n 1 813 LYS n 1 814 GLY n 1 815 GLY n 1 816 GLY n 1 817 SER n 1 818 GLY n 1 819 GLY n 1 820 GLY n 1 821 SER n 1 822 GLY n 1 823 GLY n 1 824 GLY n 1 825 SER n 1 826 TRP n 1 827 SER n 1 828 HIS n 1 829 PRO n 1 830 GLN n 1 831 PHE n 1 832 GLU n 1 833 LYS n 2 1 LEU n 2 2 HIS n 2 3 LEU n 2 4 GLN n 2 5 ASP n 2 6 ASP n 2 7 THR n 2 8 PRO n 2 9 LEU n 2 10 PHE n 2 11 PHE n 2 12 GLY n 2 13 ALA n 2 14 LYS n 2 15 PRO n 2 16 LEU n 2 17 SER n 2 18 ASP n 2 19 VAL n 2 20 SER n 2 21 LEU n 2 22 ILE n 2 23 ILE n 2 24 THR n 2 25 GLU n 2 26 PRO n 2 27 CYS n 2 28 VAL n 2 29 SER n 2 30 SER n 2 31 VAL n 2 32 TYR n 2 33 GLU n 2 34 ALA n 2 35 TRP n 2 36 ASP n 2 37 TYR n 2 38 ALA n 2 39 ALA n 2 40 PRO n 2 41 PRO n 2 42 VAL n 2 43 SER n 2 44 ASN n 2 45 LEU n 2 46 SER n 2 47 GLU n 2 48 ALA n 2 49 LEU n 2 50 SER n 2 51 GLY n 2 52 ILE n 2 53 VAL n 2 54 VAL n 2 55 LYS n 2 56 THR n 2 57 LYS n 2 58 CYS n 2 59 PRO n 2 60 VAL n 2 61 PRO n 2 62 GLU n 2 63 VAL n 2 64 ILE n 2 65 LEU n 2 66 TRP n 2 67 PHE n 2 68 LYS n 2 69 ASP n 2 70 LYS n 2 71 GLN n 2 72 MET n 2 73 ALA n 2 74 TYR n 2 75 TRP n 2 76 THR n 2 77 ASN n 2 78 PRO n 2 79 TYR n 2 80 VAL n 2 81 THR n 2 82 LEU n 2 83 LYS n 2 84 GLY n 2 85 LEU n 2 86 THR n 2 87 GLN n 2 88 SER n 2 89 VAL n 2 90 GLY n 2 91 GLU n 2 92 GLU n 2 93 HIS n 2 94 LYS n 2 95 SER n 2 96 GLY n 2 97 ASP n 2 98 ILE n 2 99 ARG n 2 100 ASP n 2 101 ALA n 2 102 LEU n 2 103 LEU n 2 104 ASP n 2 105 ALA n 2 106 LEU n 2 107 SER n 2 108 GLY n 2 109 VAL n 2 110 TRP n 2 111 VAL n 2 112 ASP n 2 113 SER n 2 114 THR n 2 115 PRO n 2 116 SER n 2 117 SER n 2 118 THR n 2 119 ASN n 2 120 ILE n 2 121 PRO n 2 122 GLU n 2 123 ASN n 2 124 GLY n 2 125 CYS n 2 126 VAL n 2 127 TRP n 2 128 GLY n 2 129 ALA n 2 130 ASP n 2 131 ARG n 2 132 LEU n 2 133 PHE n 2 134 GLN n 2 135 ARG n 2 136 VAL n 2 137 CYS n 2 138 GLN n 3 1 ASP n 3 2 ILE n 3 3 GLN n 3 4 MET n 3 5 THR n 3 6 GLN n 3 7 SER n 3 8 PRO n 3 9 SER n 3 10 SER n 3 11 VAL n 3 12 SER n 3 13 ALA n 3 14 SER n 3 15 VAL n 3 16 GLY n 3 17 ASP n 3 18 ARG n 3 19 VAL n 3 20 THR n 3 21 ILE n 3 22 THR n 3 23 CYS n 3 24 ARG n 3 25 ALA n 3 26 SER n 3 27 GLN n 3 28 GLY n 3 29 ILE n 3 30 SER n 3 31 SER n 3 32 TRP n 3 33 LEU n 3 34 ALA n 3 35 TRP n 3 36 TYR n 3 37 GLN n 3 38 GLN n 3 39 LYS n 3 40 PRO n 3 41 GLY n 3 42 LYS n 3 43 ALA n 3 44 PRO n 3 45 LYS n 3 46 LEU n 3 47 LEU n 3 48 ILE n 3 49 TYR n 3 50 ALA n 3 51 ALA n 3 52 SER n 3 53 SER n 3 54 LEU n 3 55 GLN n 3 56 SER n 3 57 GLY n 3 58 VAL n 3 59 PRO n 3 60 SER n 3 61 ARG n 3 62 PHE n 3 63 SER n 3 64 GLY n 3 65 SER n 3 66 GLY n 3 67 SER n 3 68 GLY n 3 69 THR n 3 70 ASP n 3 71 PHE n 3 72 THR n 3 73 LEU n 3 74 THR n 3 75 ILE n 3 76 SER n 3 77 SER n 3 78 LEU n 3 79 GLN n 3 80 PRO n 3 81 GLU n 3 82 ASP n 3 83 PHE n 3 84 ALA n 3 85 THR n 3 86 TYR n 3 87 TYR n 3 88 CYS n 3 89 GLN n 3 90 GLN n 3 91 ALA n 3 92 ASN n 3 93 ASN n 3 94 PHE n 3 95 PRO n 3 96 LEU n 3 97 THR n 3 98 PHE n 3 99 GLY n 3 100 GLY n 3 101 GLY n 3 102 THR n 3 103 LYS n 3 104 VAL n 3 105 GLU n 3 106 ILE n 3 107 LYS n 3 108 ARG n 3 109 THR n 3 110 VAL n 3 111 ALA n 3 112 ALA n 3 113 PRO n 3 114 SER n 3 115 VAL n 3 116 PHE n 3 117 ILE n 3 118 PHE n 3 119 PRO n 3 120 PRO n 3 121 SER n 3 122 ASP n 3 123 GLU n 3 124 GLN n 3 125 LEU n 3 126 LYS n 3 127 SER n 3 128 GLY n 3 129 THR n 3 130 ALA n 3 131 SER n 3 132 VAL n 3 133 VAL n 3 134 CYS n 3 135 LEU n 3 136 LEU n 3 137 ASN n 3 138 ASN n 3 139 PHE n 3 140 TYR n 3 141 PRO n 3 142 ARG n 3 143 GLU n 3 144 ALA n 3 145 LYS n 3 146 VAL n 3 147 GLN n 3 148 TRP n 3 149 LYS n 3 150 VAL n 3 151 ASP n 3 152 ASN n 3 153 ALA n 3 154 LEU n 3 155 GLN n 3 156 SER n 3 157 GLY n 3 158 ASN n 3 159 SER n 3 160 GLN n 3 161 GLU n 3 162 SER n 3 163 VAL n 3 164 THR n 3 165 GLU n 3 166 GLN n 3 167 ASP n 3 168 SER n 3 169 LYS n 3 170 ASP n 3 171 SER n 3 172 THR n 3 173 TYR n 3 174 SER n 3 175 LEU n 3 176 SER n 3 177 SER n 3 178 THR n 3 179 LEU n 3 180 THR n 3 181 LEU n 3 182 SER n 3 183 LYS n 3 184 ALA n 3 185 ASP n 3 186 TYR n 3 187 GLU n 3 188 LYS n 3 189 HIS n 3 190 LYS n 3 191 VAL n 3 192 TYR n 3 193 ALA n 3 194 CYS n 3 195 GLU n 3 196 VAL n 3 197 THR n 3 198 HIS n 3 199 GLN n 3 200 GLY n 3 201 LEU n 3 202 SER n 3 203 SER n 3 204 PRO n 3 205 VAL n 3 206 THR n 3 207 LYS n 3 208 SER n 3 209 PHE n 3 210 ASN n 3 211 ARG n 3 212 GLY n 3 213 GLU n 3 214 CYS n 4 1 MET n 4 2 GLU n 4 3 PHE n 4 4 GLY n 4 5 LEU n 4 6 SER n 4 7 TRP n 4 8 VAL n 4 9 PHE n 4 10 LEU n 4 11 VAL n 4 12 ALA n 4 13 ILE n 4 14 LEU n 4 15 GLU n 4 16 GLY n 4 17 VAL n 4 18 HIS n 4 19 CYS n 4 20 GLU n 4 21 VAL n 4 22 GLN n 4 23 LEU n 4 24 VAL n 4 25 GLU n 4 26 SER n 4 27 GLY n 4 28 GLY n 4 29 GLY n 4 30 VAL n 4 31 VAL n 4 32 GLN n 4 33 PRO n 4 34 GLY n 4 35 ARG n 4 36 SER n 4 37 LEU n 4 38 ARG n 4 39 LEU n 4 40 SER n 4 41 CYS n 4 42 GLY n 4 43 ALA n 4 44 SER n 4 45 GLY n 4 46 PHE n 4 47 THR n 4 48 PHE n 4 49 ASN n 4 50 THR n 4 51 TYR n 4 52 ALA n 4 53 MET n 4 54 HIS n 4 55 TRP n 4 56 VAL n 4 57 ARG n 4 58 GLN n 4 59 ALA n 4 60 PRO n 4 61 GLY n 4 62 LYS n 4 63 GLY n 4 64 VAL n 4 65 GLU n 4 66 TRP n 4 67 VAL n 4 68 ALA n 4 69 VAL n 4 70 VAL n 4 71 SER n 4 72 ASP n 4 73 GLY n 4 74 GLY n 4 75 GLY n 4 76 ASN n 4 77 ARG n 4 78 TYR n 4 79 TYR n 4 80 ALA n 4 81 ALA n 4 82 SER n 4 83 VAL n 4 84 LYS n 4 85 GLY n 4 86 ARG n 4 87 PHE n 4 88 THR n 4 89 ILE n 4 90 SER n 4 91 ARG n 4 92 ASP n 4 93 ASN n 4 94 SER n 4 95 LYS n 4 96 ASN n 4 97 THR n 4 98 LEU n 4 99 PHE n 4 100 LEU n 4 101 GLN n 4 102 LEU n 4 103 ASN n 4 104 THR n 4 105 LEU n 4 106 ARG n 4 107 PRO n 4 108 GLU n 4 109 ASP n 4 110 THR n 4 111 ALA n 4 112 VAL n 4 113 TYR n 4 114 TYR n 4 115 CYS n 4 116 ALA n 4 117 ARG n 4 118 SER n 4 119 ARG n 4 120 GLY n 4 121 ASN n 4 122 HIS n 4 123 TYR n 4 124 TYR n 4 125 TYR n 4 126 GLY n 4 127 MET n 4 128 ASP n 4 129 VAL n 4 130 TRP n 4 131 GLY n 4 132 ARG n 4 133 GLY n 4 134 THR n 4 135 THR n 4 136 VAL n 4 137 THR n 4 138 VAL n 4 139 SER n 4 140 SER n 4 141 ALA n 4 142 SER n 4 143 THR n 4 144 LYS n 4 145 GLY n 4 146 PRO n 4 147 SER n 4 148 VAL n 4 149 PHE n 4 150 PRO n 4 151 LEU n 4 152 ALA n 4 153 PRO n 4 154 SER n 4 155 SER n 4 156 LYS n 4 157 SER n 4 158 THR n 4 159 SER n 4 160 GLY n 4 161 GLY n 4 162 THR n 4 163 ALA n 4 164 ALA n 4 165 LEU n 4 166 GLY n 4 167 CYS n 4 168 LEU n 4 169 VAL n 4 170 LYS n 4 171 ASP n 4 172 TYR n 4 173 PHE n 4 174 PRO n 4 175 GLU n 4 176 PRO n 4 177 VAL n 4 178 THR n 4 179 VAL n 4 180 SER n 4 181 TRP n 4 182 ASN n 4 183 SER n 4 184 GLY n 4 185 ALA n 4 186 LEU n 4 187 THR n 4 188 SER n 4 189 GLY n 4 190 VAL n 4 191 HIS n 4 192 THR n 4 193 PHE n 4 194 PRO n 4 195 ALA n 4 196 VAL n 4 197 LEU n 4 198 GLN n 4 199 SER n 4 200 SER n 4 201 GLY n 4 202 LEU n 4 203 TYR n 4 204 SER n 4 205 LEU n 4 206 SER n 4 207 SER n 4 208 VAL n 4 209 VAL n 4 210 THR n 4 211 VAL n 4 212 PRO n 4 213 SER n 4 214 SER n 4 215 SER n 4 216 LEU n 4 217 GLY n 4 218 THR n 4 219 GLN n 4 220 THR n 4 221 TYR n 4 222 ILE n 4 223 CYS n 4 224 ASN n 4 225 VAL n 4 226 ASN n 4 227 HIS n 4 228 LYS n 4 229 PRO n 4 230 SER n 4 231 ASN n 4 232 THR n 4 233 LYS n 4 234 VAL n 4 235 ASP n 4 236 LYS n 4 237 ARG n 4 238 VAL n 4 239 GLU n 4 240 PRO n 4 241 LYS n 4 242 SER n 4 243 CYS n 4 244 ASP n 4 245 LYS n 4 246 GLY n 4 247 SER n 4 248 GLU n 4 249 ASN n 4 250 LEU n 4 251 TYR n 4 252 PHE n 4 253 GLN n 4 254 GLY n 4 255 SER n 4 256 TRP n 4 257 SER n 4 258 HIS n 4 259 PRO n 4 260 GLN n 4 261 PHE n 4 262 GLU n 4 263 LYS n 4 264 GLY n 4 265 GLY n 4 266 GLY n 4 267 SER n 4 268 GLY n 4 269 GLY n 4 270 GLY n 4 271 SER n 4 272 GLY n 4 273 GLY n 4 274 GLY n 4 275 SER n 4 276 TRP n 4 277 SER n 4 278 HIS n 4 279 PRO n 4 280 GLN n 4 281 PHE n 4 282 GLU n 4 283 LYS n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample 'Biological sequence' 1 833 HHV-3 ? 'gH, ORF37' ? ? ? ? ? ? 'Human herpesvirus 3 strain Oka vaccine' 341980 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample 'Biological sequence' 1 138 HHV-3 ? 'gL, ORF60' ? ? ? ? ? ? 'Human herpesvirus 3 strain Oka vaccine' 341980 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 3 1 sample 'Biological sequence' 1 214 ? ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 4 1 sample 'Biological sequence' 1 283 ? ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 UNP GH_VZVO Q775J3 ? 1 ;MFALVLAVVILPLWTTANKSYVTPTPATRSIGHMSALLREYSDRNMSLKLEAFYPTGFDEELIKSLHWGNDRKHVFLVIV KVNPTTHEGDVGLVIFPKYLLSPYHFKAEHRAPFPAGRFGFLSHPVTPDVSFFDSSFAPYLTTQHLVAFTTFPPNPLVWH LERAETAATAERPFGVSLLPARPTVPKNTILEHKAHFATWDALARHTFFSAEAIITNSTLRIHVPLFGSVWPIRYWATGS VLLTSDSGRVEVNIGVGFMSSLISLSSGLPIELIVVPHTVKLNAVTSDTTWFQLNPPGPDPGPSYRVYLLGRGLDMNFSK HATVDICAYPEESLDYRYHLSMAHTEALRMTTKADQHDINEESYYHIAARIATSIFALSEMGRTTEYFLLDEIVDVQYQL KFLNYILMRIGAGAHPNTISGTSDLIFADPSQLHDELSLLFGQVKPANVDYFISYDEARDQLKTAYALSRGQDHVNALSL ARRVIMSIYKGLLVKQNLNATERQALFFASMILLNFREGLENSSRVLDGRTTLLLMTSMCTAAHATQAALNIQEGLAYLN PSKHMFTIPNVYSPCMGSLRTDLTEEIHVMNLLSAIPTRPGLNEVLHTQLDESEIFDAAFKTMMIFTTWTAKDLHILHTH VPEVFTCQDAAARNGEYVLILPAVQGHSYVITRNKPQRGLVYSLADVDVYNPISVVYLSKDTCVSEHGVIETVALPHPDN LKECLYCGSVFLRYLTTGAIMDIIIIDSKDTERQLAAMGNSTIPPFNPDMHGDDSKAVLLFPNGTVVTLLGFERR ; 1 2 UNP GL_VZVO Q9J3N1 ? 2 ;LHLQDDTPLFFGAKPLSDVSLIITEPCVSSVYEAWDYAAPPVSNLSEALSGIVVKTKCPVPEVILWFKDKQMAYWTNPYV TLKGLTQSVGEEHKSGDIRDALLDALSGVWVDSTPSSTNIPENGCVWGADRLFQRVCQ ; 23 3 PDB 4XI5 4XI5 ? 3 ? 1 4 PDB 4XI5 4XI5 ? 4 ? 1 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4XI5 A 1 ? 795 ? Q775J3 1 ? 795 ? 1 795 2 2 4XI5 B 1 ? 138 ? Q9J3N1 23 ? 160 ? 23 160 3 3 4XI5 C 1 ? 214 ? 4XI5 1 ? 214 ? 1 214 4 4 4XI5 D 1 ? 283 ? 4XI5 -18 ? 264 ? -18 264 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4XI5 GLY A 796 ? UNP Q775J3 ? ? 'expression tag' 796 1 1 4XI5 SER A 797 ? UNP Q775J3 ? ? 'expression tag' 797 2 1 4XI5 GLU A 798 ? UNP Q775J3 ? ? 'expression tag' 798 3 1 4XI5 ASN A 799 ? UNP Q775J3 ? ? 'expression tag' 799 4 1 4XI5 LEU A 800 ? UNP Q775J3 ? ? 'expression tag' 800 5 1 4XI5 TYR A 801 ? UNP Q775J3 ? ? 'expression tag' 801 6 1 4XI5 PHE A 802 ? UNP Q775J3 ? ? 'expression tag' 802 7 1 4XI5 GLN A 803 ? UNP Q775J3 ? ? 'expression tag' 803 8 1 4XI5 GLY A 804 ? UNP Q775J3 ? ? 'expression tag' 804 9 1 4XI5 SER A 805 ? UNP Q775J3 ? ? 'expression tag' 805 10 1 4XI5 TRP A 806 ? UNP Q775J3 ? ? 'expression tag' 806 11 1 4XI5 SER A 807 ? UNP Q775J3 ? ? 'expression tag' 807 12 1 4XI5 HIS A 808 ? UNP Q775J3 ? ? 'expression tag' 808 13 1 4XI5 PRO A 809 ? UNP Q775J3 ? ? 'expression tag' 809 14 1 4XI5 GLN A 810 ? UNP Q775J3 ? ? 'expression tag' 810 15 1 4XI5 PHE A 811 ? UNP Q775J3 ? ? 'expression tag' 811 16 1 4XI5 GLU A 812 ? UNP Q775J3 ? ? 'expression tag' 812 17 1 4XI5 LYS A 813 ? UNP Q775J3 ? ? 'expression tag' 813 18 1 4XI5 GLY A 814 ? UNP Q775J3 ? ? 'expression tag' 814 19 1 4XI5 GLY A 815 ? UNP Q775J3 ? ? 'expression tag' 815 20 1 4XI5 GLY A 816 ? UNP Q775J3 ? ? 'expression tag' 816 21 1 4XI5 SER A 817 ? UNP Q775J3 ? ? 'expression tag' 817 22 1 4XI5 GLY A 818 ? UNP Q775J3 ? ? 'expression tag' 818 23 1 4XI5 GLY A 819 ? UNP Q775J3 ? ? 'expression tag' 819 24 1 4XI5 GLY A 820 ? UNP Q775J3 ? ? 'expression tag' 820 25 1 4XI5 SER A 821 ? UNP Q775J3 ? ? 'expression tag' 821 26 1 4XI5 GLY A 822 ? UNP Q775J3 ? ? 'expression tag' 822 27 1 4XI5 GLY A 823 ? UNP Q775J3 ? ? 'expression tag' 823 28 1 4XI5 GLY A 824 ? UNP Q775J3 ? ? 'expression tag' 824 29 1 4XI5 SER A 825 ? UNP Q775J3 ? ? 'expression tag' 825 30 1 4XI5 TRP A 826 ? UNP Q775J3 ? ? 'expression tag' 826 31 1 4XI5 SER A 827 ? UNP Q775J3 ? ? 'expression tag' 827 32 1 4XI5 HIS A 828 ? UNP Q775J3 ? ? 'expression tag' 828 33 1 4XI5 PRO A 829 ? UNP Q775J3 ? ? 'expression tag' 829 34 1 4XI5 GLN A 830 ? UNP Q775J3 ? ? 'expression tag' 830 35 1 4XI5 PHE A 831 ? UNP Q775J3 ? ? 'expression tag' 831 36 1 4XI5 GLU A 832 ? UNP Q775J3 ? ? 'expression tag' 832 37 1 4XI5 LYS A 833 ? UNP Q775J3 ? ? 'expression tag' 833 38 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 4XI5 _exptl.crystals_number ? _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 4.20 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 70.68 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH 6.0 _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '0.1M MES pH 6.0 and 4% PEG 4000' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector PIXEL _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'DECTRIS PILATUS 6M' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2013-06-21 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.00000 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'APS BEAMLINE 17-ID' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 1.00000 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline 17-ID _diffrn_source.pdbx_synchrotron_site APS # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 4XI5 _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 3.8852 _reflns.d_resolution_low 200 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 23170 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 99.1 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 6.3 _reflns.pdbx_Rmerge_I_obs 0.067 _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 24.4 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.Rmerge_I_obs 0.753 _reflns_shell.d_res_high 3.8852 _reflns_shell.d_res_low 3.97 _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_sigI_obs 1.7 _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_gt ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_gt ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_CC_half ? _reflns_shell.pdbx_R_split ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_redundancy 5.4 _reflns_shell.pdbx_rejects ? _reflns_shell.percent_possible_all ? _reflns_shell.percent_possible_gt ? _reflns_shell.percent_possible_obs ? # _refine.aniso_B[1][1] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][2] ? _refine.aniso_B[2][3] ? _refine.aniso_B[3][3] ? _refine.B_iso_max ? _refine.B_iso_mean ? _refine.B_iso_min ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.details ? _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 4XI5 _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 3.9 _refine.ls_d_res_low 37.322 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 23170 _refine.ls_number_reflns_R_free 1189 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 98.17 _refine.ls_percent_reflns_R_free 5.13 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.2467 _refine.ls_R_factor_R_free 0.2764 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.2451 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.35 _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_starting_model 'PDB entry 4XHJ' _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_R_Free_selection_details ? _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error 32.36 _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B ? _refine.overall_SU_ML 0.45 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 9632 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 92 _refine_hist.number_atoms_solvent 0 _refine_hist.number_atoms_total 9724 _refine_hist.d_res_high 3.9 _refine_hist.d_res_low 37.322 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.criterion _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.rejects _refine_ls_restr.type _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' ? 0.003 ? 9975 ? f_bond_d ? ? 'X-RAY DIFFRACTION' ? 0.944 ? 13626 ? f_angle_d ? ? 'X-RAY DIFFRACTION' ? 14.886 ? 3497 ? f_dihedral_angle_d ? ? 'X-RAY DIFFRACTION' ? 0.060 ? 1605 ? f_chiral_restr ? ? 'X-RAY DIFFRACTION' ? 0.004 ? 1727 ? f_plane_restr ? ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.R_factor_all _refine_ls_shell.R_factor_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.R_factor_R_work _refine_ls_shell.redundancy_reflns_all _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.wR_factor_all _refine_ls_shell.wR_factor_obs _refine_ls_shell.wR_factor_R_free _refine_ls_shell.wR_factor_R_work _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.pdbx_phase_error _refine_ls_shell.pdbx_fsc_work _refine_ls_shell.pdbx_fsc_free 'X-RAY DIFFRACTION' 3.8852 4.0619 . . 139 2415 88.00 . . . 0.3316 . 0.2749 . . . . . . . . . . 'X-RAY DIFFRACTION' 4.0619 4.2757 . . 156 2715 99.00 . . . 0.2954 . 0.2566 . . . . . . . . . . 'X-RAY DIFFRACTION' 4.2757 4.5432 . . 144 2758 100.00 . . . 0.2511 . 0.2279 . . . . . . . . . . 'X-RAY DIFFRACTION' 4.5432 4.8932 . . 132 2780 100.00 . . . 0.2715 . 0.2127 . . . . . . . . . . 'X-RAY DIFFRACTION' 4.8932 5.3844 . . 173 2760 100.00 . . . 0.2874 . 0.2373 . . . . . . . . . . 'X-RAY DIFFRACTION' 5.3844 6.1605 . . 165 2782 100.00 . . . 0.3286 . 0.2583 . . . . . . . . . . 'X-RAY DIFFRACTION' 6.1605 7.7501 . . 145 2831 100.00 . . . 0.3091 . 0.2858 . . . . . . . . . . 'X-RAY DIFFRACTION' 7.7501 37.3241 . . 135 2940 99.00 . . . 0.2444 . 0.2339 . . . . . . . . . . # _struct.entry_id 4XI5 _struct.title 'gHgL of varicella-zoster virus in complex with human neutralizing antibodies' _struct.pdbx_descriptor 'VZV gH, VZV gL, Fab-94 light chain, Fab-94 heavy chain' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 4XI5 _struct_keywords.text 'complex, neutralization epitope, Viral Protein-Immune System complex' _struct_keywords.pdbx_keywords 'Viral Protein/Immune System' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 5 ? G N N 5 ? H N N 5 ? I N N 5 ? J N N 6 ? K N N 7 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 GLU A 61 ? SER A 65 ? GLU A 61 SER A 65 5 ? 5 HELX_P HELX_P2 AA2 ALA A 138 ? THR A 143 ? ALA A 138 THR A 143 1 ? 6 HELX_P HELX_P3 AA3 ASN A 155 ? TRP A 159 ? ASN A 155 TRP A 159 5 ? 5 HELX_P HELX_P4 AA4 TRP A 200 ? ALA A 204 ? TRP A 200 ALA A 204 5 ? 5 HELX_P HELX_P5 AA5 ALA A 211 ? ASN A 217 ? ALA A 211 ASN A 217 1 ? 7 HELX_P HELX_P6 AA6 PRO A 225 ? SER A 229 ? PRO A 225 SER A 229 5 ? 5 HELX_P HELX_P7 AA7 ALA A 322 ? ALA A 328 ? ALA A 322 ALA A 328 1 ? 7 HELX_P HELX_P8 AA8 ASP A 335 ? LYS A 353 ? ASP A 335 LYS A 353 1 ? 19 HELX_P HELX_P9 AA9 ASN A 360 ? GLU A 386 ? ASN A 360 GLU A 386 1 ? 27 HELX_P HELX_P10 AB1 LEU A 390 ? ILE A 410 ? LEU A 390 ILE A 410 1 ? 21 HELX_P HELX_P11 AB2 ASP A 429 ? GLY A 442 ? ASP A 429 GLY A 442 1 ? 14 HELX_P HELX_P12 AB3 SER A 454 ? LEU A 468 ? SER A 454 LEU A 468 1 ? 15 HELX_P HELX_P13 AB4 HIS A 474 ? LEU A 493 ? HIS A 474 LEU A 493 1 ? 20 HELX_P HELX_P14 AB5 ASN A 499 ? LEU A 514 ? ASN A 499 LEU A 514 1 ? 16 HELX_P HELX_P15 AB6 ARG A 525 ? CYS A 540 ? ARG A 525 CYS A 540 1 ? 16 HELX_P HELX_P16 AB7 THR A 541 ? TYR A 558 ? THR A 541 TYR A 558 1 ? 18 HELX_P HELX_P17 AB8 THR A 567 ? VAL A 571 ? THR A 567 VAL A 571 5 ? 5 HELX_P HELX_P18 AB9 SER A 573 ? GLY A 577 ? SER A 573 GLY A 577 5 ? 5 HELX_P HELX_P19 AC1 GLU A 585 ? SER A 594 ? GLU A 585 SER A 594 1 ? 10 HELX_P HELX_P20 AC2 ALA A 595 ? THR A 598 ? ALA A 595 THR A 598 5 ? 4 HELX_P HELX_P21 AC3 ARG A 599 ? THR A 608 ? ARG A 599 THR A 608 1 ? 10 HELX_P HELX_P22 AC4 ASP A 611 ? TRP A 629 ? ASP A 611 TRP A 629 1 ? 19 HELX_P HELX_P23 AC5 ASP A 633 ? VAL A 641 ? ASP A 633 VAL A 641 1 ? 9 HELX_P HELX_P24 AC6 VAL A 641 ? THR A 646 ? VAL A 641 THR A 646 1 ? 6 HELX_P HELX_P25 AC7 ASP A 649 ? ASN A 654 ? ASP A 649 ASN A 654 1 ? 6 HELX_P HELX_P26 AC8 SER A 748 ? ALA A 757 ? SER A 748 ALA A 757 1 ? 10 HELX_P HELX_P27 AC9 ASP B 18 ? GLU B 25 ? ASP B 40 GLU B 47 1 ? 8 HELX_P HELX_P28 AD1 CYS B 27 ? TYR B 32 ? CYS B 49 TYR B 54 1 ? 6 HELX_P HELX_P29 AD2 ASN B 44 ? LEU B 49 ? ASN B 66 LEU B 71 1 ? 6 HELX_P HELX_P30 AD3 ASN B 77 ? VAL B 89 ? ASN B 99 VAL B 111 1 ? 13 HELX_P HELX_P31 AD4 GLY B 96 ? GLY B 108 ? GLY B 118 GLY B 130 1 ? 13 HELX_P HELX_P32 AD5 GLN C 79 ? PHE C 83 ? GLN C 79 PHE C 83 5 ? 5 HELX_P HELX_P33 AD6 SER C 121 ? LYS C 126 ? SER C 121 LYS C 126 1 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 540 SG ? ? ? 1_555 A CYS 575 SG ? ? A CYS 540 A CYS 575 1_555 ? ? ? ? ? ? ? 2.032 ? disulf2 disulf ? ? A CYS 647 SG ? ? ? 1_555 A CYS 703 SG ? ? A CYS 647 A CYS 703 1_555 ? ? ? ? ? ? ? 2.030 ? disulf3 disulf ? ? A CYS 724 SG ? ? ? 1_555 A CYS 727 SG ? ? A CYS 724 A CYS 727 1_555 ? ? ? ? ? ? ? 2.035 ? disulf4 disulf ? ? B CYS 27 SG ? ? ? 1_555 B CYS 58 SG ? ? B CYS 49 B CYS 80 1_555 ? ? ? ? ? ? ? 2.035 ? disulf5 disulf ? ? B CYS 125 SG ? ? ? 1_555 B CYS 137 SG ? ? B CYS 147 B CYS 159 1_555 ? ? ? ? ? ? ? 2.026 ? disulf6 disulf ? ? C CYS 23 SG ? ? ? 1_555 C CYS 88 SG ? ? C CYS 23 C CYS 88 1_555 ? ? ? ? ? ? ? 2.031 ? disulf7 disulf ? ? C CYS 134 SG ? ? ? 1_555 C CYS 194 SG ? ? C CYS 134 C CYS 194 1_555 ? ? ? ? ? ? ? 2.032 ? disulf8 disulf ? ? D CYS 41 SG ? ? ? 1_555 D CYS 115 SG ? ? D CYS 22 D CYS 96 1_555 ? ? ? ? ? ? ? 2.035 ? disulf9 disulf ? ? D CYS 167 SG ? ? ? 1_555 D CYS 223 SG ? ? D CYS 148 D CYS 204 1_555 ? ? ? ? ? ? ? 2.033 ? covale1 covale one ? A ASN 217 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 217 A NAG 901 1_555 ? ? ? ? ? ? ? 1.445 ? covale2 covale one ? A ASN 499 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 499 A NAG 902 1_555 ? ? ? ? ? ? ? 1.444 ? covale3 covale one ? A ASN 783 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 783 A NAG 903 1_555 ? ? ? ? ? ? ? 1.441 ? covale4 covale one ? B ASN 44 ND2 ? ? ? 1_555 H NAG . C1 ? ? B ASN 66 B NAG 800 1_555 ? ? ? ? ? ? ? 1.441 ? covale5 covale none ? D CYS 167 SG ? ? ? 1_555 D CYS 223 CB ? ? D CYS 148 D CYS 204 1_555 ? ? ? ? ? ? ? 1.583 ? covale6 covale both ? H NAG . O4 ? ? ? 1_555 I NAG . C1 ? ? B NAG 800 B NAG 801 1_555 ? ? ? ? ? ? ? 1.449 ? covale7 covale both ? I NAG . O4 ? ? ? 1_555 J BMA . C1 ? ? B NAG 801 B BMA 802 1_555 ? ? ? ? ? ? ? 1.443 ? covale8 covale one ? J BMA . O3 ? ? ? 1_555 K MAN . C1 ? ? B BMA 802 B MAN 803 1_555 ? ? ? ? ? ? ? 1.442 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 SER 7 C . ? SER 7 C PRO 8 C ? PRO 8 C 1 -6.16 2 TYR 140 C . ? TYR 140 C PRO 141 C ? PRO 141 C 1 -2.95 3 ALA 152 D . ? ALA 133 D PRO 153 D ? PRO 134 D 1 -0.83 4 PHE 173 D . ? PHE 154 D PRO 174 D ? PRO 155 D 1 -9.03 5 GLU 175 D . ? GLU 156 D PRO 176 D ? PRO 157 D 1 -10.95 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 8 ? AA2 ? 6 ? AA3 ? 3 ? AA4 ? 2 ? AA5 ? 5 ? AA6 ? 5 ? AA7 ? 4 ? AA8 ? 5 ? AA9 ? 4 ? AB1 ? 3 ? AB2 ? 2 ? AB3 ? 6 ? AB4 ? 4 ? AB5 ? 3 ? AB6 ? 4 ? AB7 ? 4 ? AB8 ? 3 ? AB9 ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? anti-parallel AA1 3 4 ? anti-parallel AA1 4 5 ? parallel AA1 5 6 ? anti-parallel AA1 6 7 ? anti-parallel AA1 7 8 ? anti-parallel AA2 1 2 ? anti-parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA2 4 5 ? anti-parallel AA2 5 6 ? anti-parallel AA3 1 2 ? anti-parallel AA3 2 3 ? anti-parallel AA4 1 2 ? anti-parallel AA5 1 2 ? anti-parallel AA5 2 3 ? anti-parallel AA5 3 4 ? anti-parallel AA5 4 5 ? parallel AA6 1 2 ? parallel AA6 2 3 ? anti-parallel AA6 3 4 ? anti-parallel AA6 4 5 ? anti-parallel AA7 1 2 ? anti-parallel AA7 2 3 ? anti-parallel AA7 3 4 ? anti-parallel AA8 1 2 ? parallel AA8 2 3 ? anti-parallel AA8 3 4 ? anti-parallel AA8 4 5 ? anti-parallel AA9 1 2 ? anti-parallel AA9 2 3 ? anti-parallel AA9 3 4 ? anti-parallel AB1 1 2 ? anti-parallel AB1 2 3 ? anti-parallel AB2 1 2 ? anti-parallel AB3 1 2 ? parallel AB3 2 3 ? anti-parallel AB3 3 4 ? anti-parallel AB3 4 5 ? anti-parallel AB3 5 6 ? anti-parallel AB4 1 2 ? parallel AB4 2 3 ? anti-parallel AB4 3 4 ? anti-parallel AB5 1 2 ? anti-parallel AB5 2 3 ? anti-parallel AB6 1 2 ? anti-parallel AB6 2 3 ? anti-parallel AB6 3 4 ? anti-parallel AB7 1 2 ? anti-parallel AB7 2 3 ? anti-parallel AB7 3 4 ? anti-parallel AB8 1 2 ? anti-parallel AB8 2 3 ? anti-parallel AB9 1 2 ? anti-parallel AB9 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 LYS A 49 ? TYR A 54 ? LYS A 49 TYR A 54 AA1 2 LEU A 37 ? ASP A 43 ? LEU A 37 ASP A 43 AA1 3 ASP A 90 ? PHE A 96 ? ASP A 90 PHE A 96 AA1 4 VAL A 75 ? LYS A 81 ? VAL A 75 LYS A 81 AA1 5 GLY B 51 ? LYS B 55 ? GLY B 73 LYS B 77 AA1 6 GLU B 62 ? PHE B 67 ? GLU B 84 PHE B 89 AA1 7 MET B 72 ? THR B 76 ? MET B 94 THR B 98 AA1 8 ALA B 13 ? LYS B 14 ? ALA B 35 LYS B 36 AA2 1 THR A 127 ? PRO A 128 ? THR A 127 PRO A 128 AA2 2 ILE A 233 ? THR A 244 ? ILE A 233 THR A 244 AA2 3 GLY A 248 ? GLY A 255 ? GLY A 248 GLY A 255 AA2 4 PHE A 258 ? LEU A 265 ? PHE A 258 LEU A 265 AA2 5 ILE A 271 ? PRO A 277 ? ILE A 271 PRO A 277 AA2 6 TYR A 305 ? LEU A 310 ? TYR A 305 LEU A 310 AA3 1 THR A 219 ? HIS A 223 ? THR A 219 HIS A 223 AA3 2 ILE A 233 ? THR A 244 ? ILE A 233 THR A 244 AA3 3 SER A 420 ? LEU A 425 ? SER A 420 LEU A 425 AA4 1 PHE A 208 ? SER A 210 ? PHE A 208 SER A 210 AA4 2 TYR A 387 ? LEU A 389 ? TYR A 387 LEU A 389 AA5 1 TYR A 657 ? PRO A 662 ? TYR A 657 PRO A 662 AA5 2 HIS A 667 ? THR A 672 ? HIS A 667 THR A 672 AA5 3 SER A 694 ? SER A 699 ? SER A 694 SER A 699 AA5 4 GLY A 679 ? SER A 683 ? GLY A 679 SER A 683 AA5 5 SER A 705 ? HIS A 707 ? SER A 705 HIS A 707 AA6 1 GLU A 711 ? VAL A 713 ? GLU A 711 VAL A 713 AA6 2 VAL A 786 ? LEU A 789 ? VAL A 786 LEU A 789 AA6 3 LYS A 776 ? LEU A 780 ? LYS A 776 LEU A 780 AA6 4 VAL A 730 ? TYR A 734 ? VAL A 730 TYR A 734 AA6 5 ILE A 740 ? ILE A 745 ? ILE A 740 ILE A 745 AA7 1 MET C 4 ? SER C 7 ? MET C 4 SER C 7 AA7 2 VAL C 19 ? ALA C 25 ? VAL C 19 ALA C 25 AA7 3 PHE C 71 ? ILE C 75 ? PHE C 71 ILE C 75 AA7 4 PHE C 62 ? SER C 65 ? PHE C 62 SER C 65 AA8 1 SER C 10 ? VAL C 11 ? SER C 10 VAL C 11 AA8 2 THR C 102 ? VAL C 104 ? THR C 102 VAL C 104 AA8 3 ALA C 84 ? GLN C 90 ? ALA C 84 GLN C 90 AA8 4 LEU C 33 ? GLN C 38 ? LEU C 33 GLN C 38 AA8 5 LYS C 45 ? ILE C 48 ? LYS C 45 ILE C 48 AA9 1 SER C 114 ? PHE C 118 ? SER C 114 PHE C 118 AA9 2 THR C 129 ? PHE C 139 ? THR C 129 PHE C 139 AA9 3 TYR C 173 ? SER C 182 ? TYR C 173 SER C 182 AA9 4 GLU C 161 ? VAL C 163 ? GLU C 161 VAL C 163 AB1 1 LYS C 145 ? GLN C 147 ? LYS C 145 GLN C 147 AB1 2 TYR C 192 ? THR C 197 ? TYR C 192 THR C 197 AB1 3 THR C 206 ? PHE C 209 ? THR C 206 PHE C 209 AB2 1 GLN D 22 ? SER D 26 ? GLN D 3 SER D 7 AB2 2 SER D 40 ? SER D 44 ? SER D 21 SER D 25 AB3 1 GLY D 29 ? VAL D 30 ? GLY D 10 VAL D 11 AB3 2 THR D 134 ? THR D 137 ? THR D 115 THR D 118 AB3 3 ALA D 111 ? SER D 118 ? ALA D 92 SER D 99 AB3 4 MET D 53 ? GLN D 58 ? MET D 34 GLN D 39 AB3 5 VAL D 64 ? VAL D 70 ? VAL D 45 VAL D 51 AB3 6 ARG D 77 ? TYR D 79 ? ARG D 58 TYR D 60 AB4 1 GLY D 29 ? VAL D 30 ? GLY D 10 VAL D 11 AB4 2 THR D 134 ? THR D 137 ? THR D 115 THR D 118 AB4 3 ALA D 111 ? SER D 118 ? ALA D 92 SER D 99 AB4 4 MET D 127 ? TRP D 130 ? MET D 108 TRP D 111 AB5 1 LEU D 37 ? ARG D 38 ? LEU D 18 ARG D 19 AB5 2 LEU D 98 ? LEU D 102 ? LEU D 79 LEU D 83 AB5 3 PHE D 87 ? ARG D 91 ? PHE D 68 ARG D 72 AB6 1 VAL D 148 ? PHE D 149 ? VAL D 129 PHE D 130 AB6 2 LEU D 165 ? TYR D 172 ? LEU D 146 TYR D 153 AB6 3 TYR D 203 ? VAL D 209 ? TYR D 184 VAL D 190 AB6 4 HIS D 191 ? THR D 192 ? HIS D 172 THR D 173 AB7 1 VAL D 148 ? PHE D 149 ? VAL D 129 PHE D 130 AB7 2 LEU D 165 ? TYR D 172 ? LEU D 146 TYR D 153 AB7 3 TYR D 203 ? VAL D 209 ? TYR D 184 VAL D 190 AB7 4 VAL D 196 ? LEU D 197 ? VAL D 177 LEU D 178 AB8 1 VAL D 177 ? TRP D 181 ? VAL D 158 TRP D 162 AB8 2 ILE D 222 ? HIS D 227 ? ILE D 203 HIS D 208 AB8 3 THR D 232 ? LYS D 233 ? THR D 213 LYS D 214 AB9 1 VAL D 177 ? TRP D 181 ? VAL D 158 TRP D 162 AB9 2 ILE D 222 ? HIS D 227 ? ILE D 203 HIS D 208 AB9 3 LYS D 236 ? ARG D 237 ? LYS D 217 ARG D 218 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 O TYR A 54 ? O TYR A 54 N LEU A 38 ? N LEU A 38 AA1 2 3 N ARG A 39 ? N ARG A 39 O LEU A 93 ? O LEU A 93 AA1 3 4 O PHE A 96 ? O PHE A 96 N VAL A 75 ? N VAL A 75 AA1 4 5 N VAL A 78 ? N VAL A 78 O VAL B 54 ? O VAL B 76 AA1 5 6 N VAL B 53 ? N VAL B 75 O ILE B 64 ? O ILE B 86 AA1 6 7 N LEU B 65 ? N LEU B 87 O TYR B 74 ? O TYR B 96 AA1 7 8 O ALA B 73 ? O ALA B 95 N LYS B 14 ? N LYS B 36 AA2 1 2 N THR A 127 ? N THR A 127 O ARG A 234 ? O ARG A 234 AA2 2 3 N VAL A 241 ? N VAL A 241 O VAL A 252 ? O VAL A 252 AA2 3 4 N ASN A 253 ? N ASN A 253 O SER A 260 ? O SER A 260 AA2 4 5 N ILE A 263 ? N ILE A 263 O ILE A 271 ? O ILE A 271 AA2 5 6 N VAL A 276 ? N VAL A 276 O ARG A 306 ? O ARG A 306 AA3 1 2 N THR A 219 ? N THR A 219 O ALA A 237 ? O ALA A 237 AA3 2 3 N LEU A 242 ? N LEU A 242 O THR A 422 ? O THR A 422 AA4 1 2 N PHE A 209 ? N PHE A 209 O PHE A 388 ? O PHE A 388 AA5 1 2 N VAL A 658 ? N VAL A 658 O ILE A 671 ? O ILE A 671 AA5 2 3 N SER A 668 ? N SER A 668 O LEU A 698 ? O LEU A 698 AA5 3 4 O VAL A 695 ? O VAL A 695 N TYR A 682 ? N TYR A 682 AA5 4 5 N VAL A 681 ? N VAL A 681 O GLU A 706 ? O GLU A 706 AA6 1 2 N GLU A 711 ? N GLU A 711 O VAL A 786 ? O VAL A 786 AA6 2 3 O VAL A 787 ? O VAL A 787 N LEU A 779 ? N LEU A 779 AA6 3 4 O VAL A 778 ? O VAL A 778 N LEU A 732 ? N LEU A 732 AA6 4 5 N PHE A 731 ? N PHE A 731 O ILE A 744 ? O ILE A 744 AA7 1 2 N THR C 5 ? N THR C 5 O ARG C 24 ? O ARG C 24 AA7 2 3 N VAL C 19 ? N VAL C 19 O ILE C 75 ? O ILE C 75 AA7 3 4 O THR C 72 ? O THR C 72 N SER C 65 ? N SER C 65 AA8 1 2 N VAL C 11 ? N VAL C 11 O LYS C 103 ? O LYS C 103 AA8 2 3 O THR C 102 ? O THR C 102 N TYR C 86 ? N TYR C 86 AA8 3 4 O GLN C 89 ? O GLN C 89 N ALA C 34 ? N ALA C 34 AA8 4 5 N TRP C 35 ? N TRP C 35 O ILE C 48 ? O ILE C 48 AA9 1 2 N PHE C 118 ? N PHE C 118 O VAL C 133 ? O VAL C 133 AA9 2 3 N LEU C 136 ? N LEU C 136 O LEU C 175 ? O LEU C 175 AA9 3 4 O SER C 176 ? O SER C 176 N SER C 162 ? N SER C 162 AB1 1 2 N GLN C 147 ? N GLN C 147 O GLU C 195 ? O GLU C 195 AB1 2 3 N TYR C 192 ? N TYR C 192 O PHE C 209 ? O PHE C 209 AB2 1 2 N VAL D 24 ? N VAL D 5 O GLY D 42 ? O GLY D 23 AB3 1 2 N GLY D 29 ? N GLY D 10 O THR D 137 ? O THR D 118 AB3 2 3 O THR D 134 ? O THR D 115 N TYR D 113 ? N TYR D 94 AB3 3 4 O ALA D 116 ? O ALA D 97 N HIS D 54 ? N HIS D 35 AB3 4 5 N ARG D 57 ? N ARG D 38 O GLU D 65 ? O GLU D 46 AB3 5 6 N VAL D 69 ? N VAL D 50 O TYR D 78 ? O TYR D 59 AB4 1 2 N GLY D 29 ? N GLY D 10 O THR D 137 ? O THR D 118 AB4 2 3 O THR D 134 ? O THR D 115 N TYR D 113 ? N TYR D 94 AB4 3 4 N ARG D 117 ? N ARG D 98 O VAL D 129 ? O VAL D 110 AB5 1 2 N LEU D 37 ? N LEU D 18 O LEU D 102 ? O LEU D 83 AB5 2 3 O GLN D 101 ? O GLN D 82 N THR D 88 ? N THR D 69 AB6 1 2 N PHE D 149 ? N PHE D 130 O LEU D 168 ? O LEU D 149 AB6 2 3 N LEU D 165 ? N LEU D 146 O VAL D 209 ? O VAL D 190 AB6 3 4 O VAL D 208 ? O VAL D 189 N HIS D 191 ? N HIS D 172 AB7 1 2 N PHE D 149 ? N PHE D 130 O LEU D 168 ? O LEU D 149 AB7 2 3 N LEU D 165 ? N LEU D 146 O VAL D 209 ? O VAL D 190 AB7 3 4 O SER D 204 ? O SER D 185 N VAL D 196 ? N VAL D 177 AB8 1 2 N SER D 180 ? N SER D 161 O ASN D 224 ? O ASN D 205 AB8 2 3 N HIS D 227 ? N HIS D 208 O THR D 232 ? O THR D 213 AB9 1 2 N SER D 180 ? N SER D 161 O ASN D 224 ? O ASN D 205 AB9 2 3 N CYS D 223 ? N CYS D 204 O LYS D 236 ? O LYS D 217 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A NAG 901 ? 4 'binding site for Mono-Saccharide NAG A 901 bound to ASN A 217' AC2 Software A NAG 902 ? 3 'binding site for Mono-Saccharide NAG A 902 bound to ASN A 499' AC3 Software A NAG 903 ? 3 'binding site for Mono-Saccharide NAG A 903 bound to ASN A 783' AC4 Software B ASN 66 ? 4 'binding site for Poly-Saccharide residues NAG B 800 through MAN B 803 bound to ASN B 66' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 ASN A 188 ? ASN A 188 . ? 3_454 ? 2 AC1 4 HIS A 193 ? HIS A 193 . ? 1_555 ? 3 AC1 4 ALA A 213 ? ALA A 213 . ? 1_555 ? 4 AC1 4 ASN A 217 ? ASN A 217 . ? 1_555 ? 5 AC2 3 ASN A 499 ? ASN A 499 . ? 1_555 ? 6 AC2 3 THR A 501 ? THR A 501 . ? 1_555 ? 7 AC2 3 GLU A 502 ? GLU A 502 . ? 1_555 ? 8 AC3 3 PHE A 781 ? PHE A 781 . ? 1_555 ? 9 AC3 3 ASN A 783 ? ASN A 783 . ? 1_555 ? 10 AC3 3 THR A 785 ? THR A 785 . ? 1_555 ? 11 AC4 4 LYS A 98 ? LYS A 98 . ? 1_555 ? 12 AC4 4 TYR A 99 ? TYR A 99 . ? 1_555 ? 13 AC4 4 SER A 102 ? SER A 102 . ? 1_555 ? 14 AC4 4 ASN B 44 ? ASN B 66 . ? 1_555 ? # _atom_sites.entry_id 4XI5 _atom_sites.fract_transf_matrix[1][1] 0.009804 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.003564 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.005704 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ALA A 1 36 ? -83.329 23.627 -14.651 1.00 85.38 ? 36 ALA A N 1 ATOM 2 C CA . ALA A 1 36 ? -82.408 24.753 -14.752 1.00 86.68 ? 36 ALA A CA 1 ATOM 3 C C . ALA A 1 36 ? -82.644 25.765 -13.636 1.00 92.15 ? 36 ALA A C 1 ATOM 4 O O . ALA A 1 36 ? -83.500 26.641 -13.756 1.00 96.22 ? 36 ALA A O 1 ATOM 5 C CB . ALA A 1 36 ? -82.542 25.424 -16.108 1.00 89.71 ? 36 ALA A CB 1 ATOM 6 N N . LEU A 1 37 ? -81.881 25.644 -12.554 1.00 89.31 ? 37 LEU A N 1 ATOM 7 C CA . LEU A 1 37 ? -82.010 26.563 -11.428 1.00 93.02 ? 37 LEU A CA 1 ATOM 8 C C . LEU A 1 37 ? -80.660 27.024 -10.877 1.00 84.99 ? 37 LEU A C 1 ATOM 9 O O . LEU A 1 37 ? -79.800 26.207 -10.542 1.00 73.21 ? 37 LEU A O 1 ATOM 10 C CB . LEU A 1 37 ? -82.838 25.928 -10.306 1.00 93.39 ? 37 LEU A CB 1 ATOM 11 C CG . LEU A 1 37 ? -84.040 26.719 -9.778 1.00 82.58 ? 37 LEU A CG 1 ATOM 12 C CD1 . LEU A 1 37 ? -84.513 26.152 -8.446 1.00 76.27 ? 37 LEU A CD1 1 ATOM 13 C CD2 . LEU A 1 37 ? -83.719 28.201 -9.654 1.00 83.67 ? 37 LEU A CD2 1 ATOM 14 N N . LEU A 1 38 ? -80.487 28.340 -10.791 1.00 92.04 ? 38 LEU A N 1 ATOM 15 C CA . LEU A 1 38 ? -79.342 28.939 -10.111 1.00 82.62 ? 38 LEU A CA 1 ATOM 16 C C . LEU A 1 38 ? -79.831 29.661 -8.862 1.00 94.40 ? 38 LEU A C 1 ATOM 17 O O . LEU A 1 38 ? -80.747 30.478 -8.930 1.00 106.99 ? 38 LEU A O 1 ATOM 18 C CB . LEU A 1 38 ? -78.619 29.926 -11.030 1.00 75.53 ? 38 LEU A CB 1 ATOM 19 C CG . LEU A 1 38 ? -77.754 31.006 -10.368 1.00 73.91 ? 38 LEU A CG 1 ATOM 20 C CD1 . LEU A 1 38 ? -76.551 30.400 -9.668 1.00 79.43 ? 38 LEU A CD1 1 ATOM 21 C CD2 . LEU A 1 38 ? -77.311 32.048 -11.385 1.00 76.19 ? 38 LEU A CD2 1 ATOM 22 N N . ARG A 1 39 ? -79.221 29.360 -7.722 1.00 88.41 ? 39 ARG A N 1 ATOM 23 C CA . ARG A 1 39 ? -79.638 29.966 -6.465 1.00 92.38 ? 39 ARG A CA 1 ATOM 24 C C . ARG A 1 39 ? -78.454 30.475 -5.652 1.00 99.37 ? 39 ARG A C 1 ATOM 25 O O . ARG A 1 39 ? -77.550 29.713 -5.311 1.00 97.36 ? 39 ARG A O 1 ATOM 26 C CB . ARG A 1 39 ? -80.458 28.986 -5.657 1.00 97.58 ? 39 ARG A CB 1 ATOM 27 N N . GLU A 1 40 ? -78.474 31.766 -5.337 1.00 106.64 ? 40 GLU A N 1 ATOM 28 C CA . GLU A 1 40 ? -77.405 32.391 -4.568 1.00 106.33 ? 40 GLU A CA 1 ATOM 29 C C . GLU A 1 40 ? -77.883 32.675 -3.145 1.00 105.30 ? 40 GLU A C 1 ATOM 30 O O . GLU A 1 40 ? -78.740 33.533 -2.930 1.00 108.79 ? 40 GLU A O 1 ATOM 31 C CB . GLU A 1 40 ? -76.957 33.682 -5.255 1.00 117.88 ? 40 GLU A CB 1 ATOM 32 C CG . GLU A 1 40 ? -76.525 33.485 -6.706 1.00 125.93 ? 40 GLU A CG 1 ATOM 33 C CD . GLU A 1 40 ? -76.697 34.734 -7.552 1.00 127.27 ? 40 GLU A CD 1 ATOM 34 O OE1 . GLU A 1 40 ? -77.086 35.784 -6.999 1.00 133.55 ? 40 GLU A OE1 1 ATOM 35 O OE2 . GLU A 1 40 ? -76.452 34.662 -8.775 1.00 118.24 ? 40 GLU A OE2 1 ATOM 36 N N . TYR A 1 41 ? -77.324 31.952 -2.178 1.00 106.26 ? 41 TYR A N 1 ATOM 37 C CA . TYR A 1 41 ? -77.787 32.020 -0.794 1.00 97.41 ? 41 TYR A CA 1 ATOM 38 C C . TYR A 1 41 ? -76.925 32.937 0.065 1.00 99.43 ? 41 TYR A C 1 ATOM 39 O O . TYR A 1 41 ? -75.922 33.481 -0.396 1.00 114.60 ? 41 TYR A O 1 ATOM 40 C CB . TYR A 1 41 ? -77.751 30.625 -0.159 1.00 92.30 ? 41 TYR A CB 1 ATOM 41 C CG . TYR A 1 41 ? -78.761 29.631 -0.685 1.00 100.54 ? 41 TYR A CG 1 ATOM 42 C CD1 . TYR A 1 41 ? -79.799 29.180 0.119 1.00 107.54 ? 41 TYR A CD1 1 ATOM 43 C CD2 . TYR A 1 41 ? -78.665 29.123 -1.974 1.00 101.35 ? 41 TYR A CD2 1 ATOM 44 C CE1 . TYR A 1 41 ? -80.724 28.266 -0.350 1.00 123.42 ? 41 TYR A CE1 1 ATOM 45 C CE2 . TYR A 1 41 ? -79.583 28.207 -2.450 1.00 105.79 ? 41 TYR A CE2 1 ATOM 46 C CZ . TYR A 1 41 ? -80.611 27.783 -1.636 1.00 122.57 ? 41 TYR A CZ 1 ATOM 47 O OH . TYR A 1 41 ? -81.529 26.872 -2.109 1.00 120.84 ? 41 TYR A OH 1 ATOM 48 N N . SER A 1 42 ? -77.336 33.105 1.318 1.00 88.95 ? 42 SER A N 1 ATOM 49 C CA . SER A 1 42 ? -76.468 33.628 2.369 1.00 90.14 ? 42 SER A CA 1 ATOM 50 C C . SER A 1 42 ? -76.724 32.859 3.664 1.00 91.22 ? 42 SER A C 1 ATOM 51 O O . SER A 1 42 ? -77.842 32.857 4.177 1.00 104.53 ? 42 SER A O 1 ATOM 52 C CB . SER A 1 42 ? -76.696 35.126 2.583 1.00 91.44 ? 42 SER A CB 1 ATOM 53 O OG . SER A 1 42 ? -76.007 35.897 1.613 1.00 97.62 ? 42 SER A OG 1 ATOM 54 N N . ASP A 1 43 ? -75.685 32.225 4.199 1.00 90.90 ? 43 ASP A N 1 ATOM 55 C CA . ASP A 1 43 ? -75.804 31.451 5.431 1.00 98.23 ? 43 ASP A CA 1 ATOM 56 C C . ASP A 1 43 ? -75.653 32.389 6.626 1.00 114.70 ? 43 ASP A C 1 ATOM 57 O O . ASP A 1 43 ? -74.830 33.301 6.593 1.00 117.00 ? 43 ASP A O 1 ATOM 58 C CB . ASP A 1 43 ? -74.725 30.365 5.469 1.00 101.72 ? 43 ASP A CB 1 ATOM 59 C CG . ASP A 1 43 ? -75.015 29.280 6.489 1.00 114.05 ? 43 ASP A CG 1 ATOM 60 O OD1 . ASP A 1 43 ? -75.859 29.501 7.383 1.00 125.46 ? 43 ASP A OD1 1 ATOM 61 O OD2 . ASP A 1 43 ? -74.388 28.203 6.399 1.00 113.06 ? 43 ASP A OD2 1 ATOM 62 N N . ARG A 1 44 ? -76.444 32.171 7.676 1.00 113.81 ? 44 ARG A N 1 ATOM 63 C CA . ARG A 1 44 ? -76.416 33.054 8.844 1.00 107.87 ? 44 ARG A CA 1 ATOM 64 C C . ARG A 1 44 ? -76.075 32.317 10.142 1.00 110.67 ? 44 ARG A C 1 ATOM 65 O O . ARG A 1 44 ? -74.956 32.407 10.644 1.00 117.19 ? 44 ARG A O 1 ATOM 66 C CB . ARG A 1 44 ? -77.747 33.784 8.982 1.00 97.81 ? 44 ARG A CB 1 ATOM 67 N N . ASN A 1 45 ? -77.049 31.587 10.674 1.00 118.60 ? 45 ASN A N 1 ATOM 68 C CA . ASN A 1 45 ? -76.863 30.759 11.861 1.00 123.53 ? 45 ASN A CA 1 ATOM 69 C C . ASN A 1 45 ? -77.299 29.373 11.427 1.00 134.14 ? 45 ASN A C 1 ATOM 70 O O . ASN A 1 45 ? -77.598 29.184 10.248 1.00 136.01 ? 45 ASN A O 1 ATOM 71 C CB . ASN A 1 45 ? -77.732 31.271 13.011 1.00 124.87 ? 45 ASN A CB 1 ATOM 72 C CG . ASN A 1 45 ? -77.326 30.699 14.357 1.00 113.57 ? 45 ASN A CG 1 ATOM 73 O OD1 . ASN A 1 45 ? -76.326 29.990 14.469 1.00 103.21 ? 45 ASN A OD1 1 ATOM 74 N ND2 . ASN A 1 45 ? -78.099 31.015 15.390 1.00 107.27 ? 45 ASN A ND2 1 ATOM 75 N N . MET A 1 46 ? -77.360 28.394 12.326 1.00 135.47 ? 46 MET A N 1 ATOM 76 C CA . MET A 1 46 ? -77.797 27.097 11.837 1.00 132.83 ? 46 MET A CA 1 ATOM 77 C C . MET A 1 46 ? -79.304 26.988 12.014 1.00 117.23 ? 46 MET A C 1 ATOM 78 O O . MET A 1 46 ? -79.809 26.621 13.077 1.00 123.82 ? 46 MET A O 1 ATOM 79 C CB . MET A 1 46 ? -77.098 25.985 12.623 1.00 130.15 ? 46 MET A CB 1 ATOM 80 C CG . MET A 1 46 ? -76.034 26.498 13.588 1.00 129.84 ? 46 MET A CG 1 ATOM 81 S SD . MET A 1 46 ? -75.278 25.211 14.603 1.00 165.73 ? 46 MET A SD 1 ATOM 82 C CE . MET A 1 46 ? -74.455 24.228 13.352 1.00 131.67 ? 46 MET A CE 1 ATOM 83 N N . SER A 1 47 ? -80.008 27.318 10.937 1.00 103.66 ? 47 SER A N 1 ATOM 84 C CA . SER A 1 47 ? -81.418 27.026 10.752 1.00 117.20 ? 47 SER A CA 1 ATOM 85 C C . SER A 1 47 ? -81.638 26.680 9.286 1.00 118.15 ? 47 SER A C 1 ATOM 86 O O . SER A 1 47 ? -81.929 25.543 8.909 1.00 111.37 ? 47 SER A O 1 ATOM 87 C CB . SER A 1 47 ? -82.257 28.240 11.146 1.00 129.14 ? 47 SER A CB 1 ATOM 88 O OG . SER A 1 47 ? -81.677 29.435 10.646 1.00 120.27 ? 47 SER A OG 1 ATOM 89 N N . LEU A 1 48 ? -81.470 27.722 8.475 1.00 113.13 ? 48 LEU A N 1 ATOM 90 C CA . LEU A 1 48 ? -81.658 27.703 7.032 1.00 111.49 ? 48 LEU A CA 1 ATOM 91 C C . LEU A 1 48 ? -80.994 28.978 6.501 1.00 113.76 ? 48 LEU A C 1 ATOM 92 O O . LEU A 1 48 ? -80.348 29.697 7.265 1.00 107.05 ? 48 LEU A O 1 ATOM 93 C CB . LEU A 1 48 ? -83.135 27.674 6.685 1.00 84.26 ? 48 LEU A CB 1 ATOM 94 N N . LYS A 1 49 ? -81.139 29.265 5.210 1.00 112.94 ? 49 LYS A N 1 ATOM 95 C CA . LYS A 1 49 ? -80.460 30.422 4.618 1.00 89.59 ? 49 LYS A CA 1 ATOM 96 C C . LYS A 1 49 ? -81.339 31.270 3.695 1.00 91.04 ? 49 LYS A C 1 ATOM 97 O O . LYS A 1 49 ? -82.176 30.744 2.963 1.00 106.64 ? 49 LYS A O 1 ATOM 98 C CB . LYS A 1 49 ? -79.203 29.971 3.882 1.00 95.61 ? 49 LYS A CB 1 ATOM 99 N N . LEU A 1 50 ? -81.131 32.585 3.731 1.00 83.46 ? 50 LEU A N 1 ATOM 100 C CA . LEU A 1 50 ? -81.813 33.505 2.822 1.00 90.55 ? 50 LEU A CA 1 ATOM 101 C C . LEU A 1 50 ? -81.266 33.325 1.408 1.00 101.80 ? 50 LEU A C 1 ATOM 102 O O . LEU A 1 50 ? -80.081 33.045 1.236 1.00 110.64 ? 50 LEU A O 1 ATOM 103 C CB . LEU A 1 50 ? -81.610 34.961 3.256 1.00 83.75 ? 50 LEU A CB 1 ATOM 104 C CG . LEU A 1 50 ? -81.733 35.368 4.728 1.00 87.89 ? 50 LEU A CG 1 ATOM 105 C CD1 . LEU A 1 50 ? -80.401 35.219 5.456 1.00 76.26 ? 50 LEU A CD1 1 ATOM 106 C CD2 . LEU A 1 50 ? -82.255 36.796 4.851 1.00 93.00 ? 50 LEU A CD2 1 ATOM 107 N N . GLU A 1 51 ? -82.121 33.491 0.400 1.00 99.64 ? 51 GLU A N 1 ATOM 108 C CA . GLU A 1 51 ? -81.692 33.337 -0.991 1.00 104.52 ? 51 GLU A CA 1 ATOM 109 C C . GLU A 1 51 ? -82.665 33.944 -1.996 1.00 110.06 ? 51 GLU A C 1 ATOM 110 O O . GLU A 1 51 ? -83.712 34.474 -1.627 1.00 120.43 ? 51 GLU A O 1 ATOM 111 C CB . GLU A 1 51 ? -81.471 31.866 -1.313 1.00 109.79 ? 51 GLU A CB 1 ATOM 112 N N . ALA A 1 52 ? -82.298 33.859 -3.272 1.00 111.17 ? 52 ALA A N 1 ATOM 113 C CA . ALA A 1 52 ? -83.181 34.229 -4.372 1.00 115.86 ? 52 ALA A CA 1 ATOM 114 C C . ALA A 1 52 ? -82.974 33.260 -5.532 1.00 116.07 ? 52 ALA A C 1 ATOM 115 O O . ALA A 1 52 ? -81.839 32.974 -5.913 1.00 112.71 ? 52 ALA A O 1 ATOM 116 C CB . ALA A 1 52 ? -82.922 35.657 -4.813 1.00 116.69 ? 52 ALA A CB 1 ATOM 117 N N . PHE A 1 53 ? -84.070 32.757 -6.089 1.00 121.51 ? 53 PHE A N 1 ATOM 118 C CA . PHE A 1 53 ? -83.994 31.757 -7.148 1.00 121.72 ? 53 PHE A CA 1 ATOM 119 C C . PHE A 1 53 ? -84.123 32.393 -8.527 1.00 122.88 ? 53 PHE A C 1 ATOM 120 O O . PHE A 1 53 ? -85.053 33.159 -8.783 1.00 125.49 ? 53 PHE A O 1 ATOM 121 C CB . PHE A 1 53 ? -85.077 30.691 -6.954 1.00 116.06 ? 53 PHE A CB 1 ATOM 122 C CG . PHE A 1 53 ? -85.095 30.091 -5.576 1.00 103.92 ? 53 PHE A CG 1 ATOM 123 C CD1 . PHE A 1 53 ? -84.260 29.035 -5.254 1.00 101.67 ? 53 PHE A CD1 1 ATOM 124 C CD2 . PHE A 1 53 ? -85.948 30.585 -4.603 1.00 104.05 ? 53 PHE A CD2 1 ATOM 125 C CE1 . PHE A 1 53 ? -84.272 28.485 -3.986 1.00 99.78 ? 53 PHE A CE1 1 ATOM 126 C CE2 . PHE A 1 53 ? -85.967 30.038 -3.333 1.00 119.15 ? 53 PHE A CE2 1 ATOM 127 C CZ . PHE A 1 53 ? -85.128 28.986 -3.025 1.00 112.23 ? 53 PHE A CZ 1 ATOM 128 N N . TYR A 1 54 ? -83.185 32.073 -9.412 1.00 118.76 ? 54 TYR A N 1 ATOM 129 C CA . TYR A 1 54 ? -83.218 32.600 -10.771 1.00 119.99 ? 54 TYR A CA 1 ATOM 130 C C . TYR A 1 54 ? -83.172 31.480 -11.806 1.00 116.33 ? 54 TYR A C 1 ATOM 131 O O . TYR A 1 54 ? -82.128 31.241 -12.414 1.00 110.46 ? 54 TYR A O 1 ATOM 132 C CB . TYR A 1 54 ? -82.049 33.560 -11.011 1.00 113.84 ? 54 TYR A CB 1 ATOM 133 C CG . TYR A 1 54 ? -81.574 34.301 -9.780 1.00 123.47 ? 54 TYR A CG 1 ATOM 134 C CD1 . TYR A 1 54 ? -82.244 35.426 -9.315 1.00 127.46 ? 54 TYR A CD1 1 ATOM 135 C CD2 . TYR A 1 54 ? -80.442 33.885 -9.092 1.00 121.19 ? 54 TYR A CD2 1 ATOM 136 C CE1 . TYR A 1 54 ? -81.805 36.108 -8.191 1.00 131.95 ? 54 TYR A CE1 1 ATOM 137 C CE2 . TYR A 1 54 ? -79.996 34.559 -7.969 1.00 123.79 ? 54 TYR A CE2 1 ATOM 138 C CZ . TYR A 1 54 ? -80.679 35.669 -7.523 1.00 131.82 ? 54 TYR A CZ 1 ATOM 139 O OH . TYR A 1 54 ? -80.232 36.340 -6.405 1.00 123.51 ? 54 TYR A OH 1 ATOM 140 N N . PRO A 1 55 ? -84.301 30.783 -12.006 1.00 124.78 ? 55 PRO A N 1 ATOM 141 C CA . PRO A 1 55 ? -84.334 29.813 -13.105 1.00 125.25 ? 55 PRO A CA 1 ATOM 142 C C . PRO A 1 55 ? -84.157 30.545 -14.431 1.00 128.23 ? 55 PRO A C 1 ATOM 143 O O . PRO A 1 55 ? -84.859 31.523 -14.688 1.00 133.74 ? 55 PRO A O 1 ATOM 144 C CB . PRO A 1 55 ? -85.740 29.212 -13.001 1.00 131.72 ? 55 PRO A CB 1 ATOM 145 C CG . PRO A 1 55 ? -86.548 30.237 -12.272 1.00 127.09 ? 55 PRO A CG 1 ATOM 146 C CD . PRO A 1 55 ? -85.598 30.894 -11.316 1.00 130.09 ? 55 PRO A CD 1 ATOM 147 N N . THR A 1 56 ? -83.229 30.084 -15.262 1.00 122.22 ? 56 THR A N 1 ATOM 148 C CA . THR A 1 56 ? -82.912 30.808 -16.486 1.00 128.51 ? 56 THR A CA 1 ATOM 149 C C . THR A 1 56 ? -83.809 30.409 -17.652 1.00 134.52 ? 56 THR A C 1 ATOM 150 O O . THR A 1 56 ? -84.704 31.160 -18.042 1.00 131.02 ? 56 THR A O 1 ATOM 151 C CB . THR A 1 56 ? -81.438 30.609 -16.889 1.00 122.17 ? 56 THR A CB 1 ATOM 152 O OG1 . THR A 1 56 ? -81.119 29.212 -16.867 1.00 117.44 ? 56 THR A OG1 1 ATOM 153 C CG2 . THR A 1 56 ? -80.520 31.343 -15.926 1.00 118.28 ? 56 THR A CG2 1 ATOM 154 N N . GLY A 1 57 ? -83.567 29.226 -18.207 1.00 134.35 ? 57 GLY A N 1 ATOM 155 C CA . GLY A 1 57 ? -84.305 28.776 -19.371 1.00 131.52 ? 57 GLY A CA 1 ATOM 156 C C . GLY A 1 57 ? -85.306 27.652 -19.178 1.00 139.46 ? 57 GLY A C 1 ATOM 157 O O . GLY A 1 57 ? -86.007 27.292 -20.124 1.00 149.55 ? 57 GLY A O 1 ATOM 158 N N . PHE A 1 58 ? -85.397 27.095 -17.973 1.00 131.73 ? 58 PHE A N 1 ATOM 159 C CA . PHE A 1 58 ? -86.226 25.903 -17.787 1.00 125.35 ? 58 PHE A CA 1 ATOM 160 C C . PHE A 1 58 ? -86.853 25.742 -16.405 1.00 113.53 ? 58 PHE A C 1 ATOM 161 O O . PHE A 1 58 ? -86.787 26.639 -15.563 1.00 103.60 ? 58 PHE A O 1 ATOM 162 C CB . PHE A 1 58 ? -85.441 24.652 -18.158 1.00 129.41 ? 58 PHE A CB 1 ATOM 163 N N . ASP A 1 59 ? -87.459 24.577 -16.189 1.00 120.99 ? 59 ASP A N 1 ATOM 164 C CA . ASP A 1 59 ? -88.213 24.303 -14.971 1.00 121.07 ? 59 ASP A CA 1 ATOM 165 C C . ASP A 1 59 ? -87.579 23.235 -14.082 1.00 114.28 ? 59 ASP A C 1 ATOM 166 O O . ASP A 1 59 ? -87.216 22.151 -14.537 1.00 113.93 ? 59 ASP A O 1 ATOM 167 C CB . ASP A 1 59 ? -89.655 23.906 -15.311 1.00 133.35 ? 59 ASP A CB 1 ATOM 168 C CG . ASP A 1 59 ? -89.733 22.649 -16.164 1.00 143.82 ? 59 ASP A CG 1 ATOM 169 O OD1 . ASP A 1 59 ? -88.782 22.387 -16.930 1.00 151.66 ? 59 ASP A OD1 1 ATOM 170 O OD2 . ASP A 1 59 ? -90.747 21.923 -16.070 1.00 138.88 ? 59 ASP A OD2 1 ATOM 171 N N . GLU A 1 60 ? -87.450 23.573 -12.805 1.00 108.24 ? 60 GLU A N 1 ATOM 172 C CA . GLU A 1 60 ? -87.083 22.634 -11.760 1.00 102.86 ? 60 GLU A CA 1 ATOM 173 C C . GLU A 1 60 ? -88.260 22.728 -10.808 1.00 103.07 ? 60 GLU A C 1 ATOM 174 O O . GLU A 1 60 ? -89.025 23.690 -10.882 1.00 105.14 ? 60 GLU A O 1 ATOM 175 C CB . GLU A 1 60 ? -85.792 23.097 -11.072 1.00 94.49 ? 60 GLU A CB 1 ATOM 176 C CG . GLU A 1 60 ? -85.344 22.274 -9.863 1.00 87.71 ? 60 GLU A CG 1 ATOM 177 C CD . GLU A 1 60 ? -84.645 20.987 -10.249 1.00 86.20 ? 60 GLU A CD 1 ATOM 178 O OE1 . GLU A 1 60 ? -84.409 20.776 -11.456 1.00 93.54 ? 60 GLU A OE1 1 ATOM 179 O OE2 . GLU A 1 60 ? -84.325 20.187 -9.344 1.00 82.12 ? 60 GLU A OE2 1 ATOM 180 N N . GLU A 1 61 ? -88.444 21.750 -9.930 1.00 98.67 ? 61 GLU A N 1 ATOM 181 C CA . GLU A 1 61 ? -89.478 21.913 -8.924 1.00 92.23 ? 61 GLU A CA 1 ATOM 182 C C . GLU A 1 61 ? -88.910 22.935 -7.955 1.00 86.10 ? 61 GLU A C 1 ATOM 183 O O . GLU A 1 61 ? -87.873 22.707 -7.336 1.00 86.51 ? 61 GLU A O 1 ATOM 184 C CB . GLU A 1 61 ? -89.766 20.600 -8.227 1.00 81.65 ? 61 GLU A CB 1 ATOM 185 N N . LEU A 1 62 ? -89.594 24.068 -7.830 1.00 80.08 ? 62 LEU A N 1 ATOM 186 C CA . LEU A 1 62 ? -89.079 25.174 -7.036 1.00 75.68 ? 62 LEU A CA 1 ATOM 187 C C . LEU A 1 62 ? -89.244 24.858 -5.561 1.00 85.50 ? 62 LEU A C 1 ATOM 188 O O . LEU A 1 62 ? -88.539 25.402 -4.714 1.00 88.84 ? 62 LEU A O 1 ATOM 189 C CB . LEU A 1 62 ? -89.784 26.468 -7.398 1.00 69.02 ? 62 LEU A CB 1 ATOM 190 N N . ILE A 1 63 ? -90.185 23.967 -5.266 1.00 92.32 ? 63 ILE A N 1 ATOM 191 C CA . ILE A 1 63 ? -90.419 23.511 -3.905 1.00 87.11 ? 63 ILE A CA 1 ATOM 192 C C . ILE A 1 63 ? -89.465 22.375 -3.557 1.00 90.38 ? 63 ILE A C 1 ATOM 193 O O . ILE A 1 63 ? -89.475 21.865 -2.436 1.00 94.12 ? 63 ILE A O 1 ATOM 194 C CB . ILE A 1 63 ? -91.860 23.068 -3.733 1.00 86.27 ? 63 ILE A CB 1 ATOM 195 N N . LYS A 1 64 ? -88.647 21.976 -4.527 1.00 89.05 ? 64 LYS A N 1 ATOM 196 C CA . LYS A 1 64 ? -87.614 20.978 -4.288 1.00 87.32 ? 64 LYS A CA 1 ATOM 197 C C . LYS A 1 64 ? -86.299 21.655 -3.930 1.00 83.19 ? 64 LYS A C 1 ATOM 198 O O . LYS A 1 64 ? -85.292 20.991 -3.716 1.00 84.11 ? 64 LYS A O 1 ATOM 199 C CB . LYS A 1 64 ? -87.436 20.086 -5.505 1.00 76.40 ? 64 LYS A CB 1 ATOM 200 N N . SER A 1 65 ? -86.308 22.982 -3.878 1.00 85.91 ? 65 SER A N 1 ATOM 201 C CA . SER A 1 65 ? -85.120 23.724 -3.478 1.00 85.36 ? 65 SER A CA 1 ATOM 202 C C . SER A 1 65 ? -85.039 23.782 -1.959 1.00 93.69 ? 65 SER A C 1 ATOM 203 O O . SER A 1 65 ? -84.021 24.179 -1.395 1.00 106.43 ? 65 SER A O 1 ATOM 204 C CB . SER A 1 65 ? -85.134 25.135 -4.064 1.00 85.51 ? 65 SER A CB 1 ATOM 205 O OG . SER A 1 65 ? -86.101 25.942 -3.417 1.00 99.67 ? 65 SER A OG 1 ATOM 206 N N . LEU A 1 66 ? -86.125 23.386 -1.303 1.00 85.99 ? 66 LEU A N 1 ATOM 207 C CA . LEU A 1 66 ? -86.147 23.285 0.150 1.00 84.97 ? 66 LEU A CA 1 ATOM 208 C C . LEU A 1 66 ? -85.266 22.125 0.605 1.00 100.80 ? 66 LEU A C 1 ATOM 209 O O . LEU A 1 66 ? -84.537 22.230 1.593 1.00 102.01 ? 66 LEU A O 1 ATOM 210 C CB . LEU A 1 66 ? -87.570 23.091 0.640 1.00 70.49 ? 66 LEU A CB 1 ATOM 211 N N . HIS A 1 67 ? -85.342 21.022 -0.132 1.00 101.67 ? 67 HIS A N 1 ATOM 212 C CA . HIS A 1 67 ? -84.534 19.836 0.127 1.00 109.23 ? 67 HIS A CA 1 ATOM 213 C C . HIS A 1 67 ? -83.771 19.497 -1.148 1.00 112.45 ? 67 HIS A C 1 ATOM 214 O O . HIS A 1 67 ? -84.391 19.125 -2.142 1.00 112.71 ? 67 HIS A O 1 ATOM 215 C CB . HIS A 1 67 ? -85.452 18.677 0.529 1.00 112.51 ? 67 HIS A CB 1 ATOM 216 C CG . HIS A 1 67 ? -84.876 17.320 0.270 1.00 126.26 ? 67 HIS A CG 1 ATOM 217 N ND1 . HIS A 1 67 ? -83.699 16.886 0.841 1.00 132.07 ? 67 HIS A ND1 1 ATOM 218 C CD2 . HIS A 1 67 ? -85.324 16.294 -0.493 1.00 124.43 ? 67 HIS A CD2 1 ATOM 219 C CE1 . HIS A 1 67 ? -83.445 15.653 0.438 1.00 131.66 ? 67 HIS A CE1 1 ATOM 220 N NE2 . HIS A 1 67 ? -84.416 15.272 -0.373 1.00 130.68 ? 67 HIS A NE2 1 ATOM 221 N N . TRP A 1 68 ? -82.438 19.580 -1.101 1.00 109.91 ? 68 TRP A N 1 ATOM 222 C CA . TRP A 1 68 ? -81.598 19.589 -2.310 1.00 101.14 ? 68 TRP A CA 1 ATOM 223 C C . TRP A 1 68 ? -81.969 18.478 -3.266 1.00 105.26 ? 68 TRP A C 1 ATOM 224 O O . TRP A 1 68 ? -82.063 17.319 -2.860 1.00 110.08 ? 68 TRP A O 1 ATOM 225 C CB . TRP A 1 68 ? -80.117 19.410 -1.958 1.00 102.74 ? 68 TRP A CB 1 ATOM 226 C CG . TRP A 1 68 ? -79.384 20.637 -1.493 1.00 101.88 ? 68 TRP A CG 1 ATOM 227 C CD1 . TRP A 1 68 ? -78.389 20.683 -0.560 1.00 90.55 ? 68 TRP A CD1 1 ATOM 228 C CD2 . TRP A 1 68 ? -79.567 21.987 -1.948 1.00 93.81 ? 68 TRP A CD2 1 ATOM 229 N NE1 . TRP A 1 68 ? -77.946 21.972 -0.400 1.00 79.11 ? 68 TRP A NE1 1 ATOM 230 C CE2 . TRP A 1 68 ? -78.653 22.792 -1.240 1.00 93.05 ? 68 TRP A CE2 1 ATOM 231 C CE3 . TRP A 1 68 ? -80.415 22.593 -2.881 1.00 76.60 ? 68 TRP A CE3 1 ATOM 232 C CZ2 . TRP A 1 68 ? -78.567 24.165 -1.433 1.00 90.19 ? 68 TRP A CZ2 1 ATOM 233 C CZ3 . TRP A 1 68 ? -80.332 23.952 -3.064 1.00 78.71 ? 68 TRP A CZ3 1 ATOM 234 C CH2 . TRP A 1 68 ? -79.409 24.725 -2.351 1.00 85.52 ? 68 TRP A CH2 1 ATOM 235 N N . GLY A 1 69 ? -82.186 18.821 -4.535 1.00 103.50 ? 69 GLY A N 1 ATOM 236 C CA . GLY A 1 69 ? -82.770 17.839 -5.419 1.00 115.24 ? 69 GLY A CA 1 ATOM 237 C C . GLY A 1 69 ? -81.810 16.692 -5.620 1.00 102.59 ? 69 GLY A C 1 ATOM 238 O O . GLY A 1 69 ? -80.759 16.824 -6.248 1.00 91.05 ? 69 GLY A O 1 ATOM 239 N N . ASN A 1 70 ? -82.198 15.559 -5.053 1.00 112.02 ? 70 ASN A N 1 ATOM 240 C CA . ASN A 1 70 ? -81.608 14.267 -5.331 1.00 111.92 ? 70 ASN A CA 1 ATOM 241 C C . ASN A 1 70 ? -82.562 13.467 -6.203 1.00 111.97 ? 70 ASN A C 1 ATOM 242 O O . ASN A 1 70 ? -82.242 12.372 -6.667 1.00 110.94 ? 70 ASN A O 1 ATOM 243 C CB . ASN A 1 70 ? -81.364 13.552 -4.009 1.00 115.67 ? 70 ASN A CB 1 ATOM 244 C CG . ASN A 1 70 ? -82.409 13.906 -2.962 1.00 122.12 ? 70 ASN A CG 1 ATOM 245 O OD1 . ASN A 1 70 ? -83.571 14.153 -3.290 1.00 116.82 ? 70 ASN A OD1 1 ATOM 246 N ND2 . ASN A 1 70 ? -81.998 13.951 -1.702 1.00 123.50 ? 70 ASN A ND2 1 ATOM 247 N N . ASP A 1 71 ? -83.742 14.040 -6.422 1.00 108.88 ? 71 ASP A N 1 ATOM 248 C CA . ASP A 1 71 ? -84.867 13.314 -6.997 1.00 113.16 ? 71 ASP A CA 1 ATOM 249 C C . ASP A 1 71 ? -84.736 13.185 -8.506 1.00 112.64 ? 71 ASP A C 1 ATOM 250 O O . ASP A 1 71 ? -84.975 12.118 -9.074 1.00 117.16 ? 71 ASP A O 1 ATOM 251 C CB . ASP A 1 71 ? -86.180 14.019 -6.642 1.00 123.83 ? 71 ASP A CB 1 ATOM 252 C CG . ASP A 1 71 ? -87.399 13.155 -6.909 1.00 124.95 ? 71 ASP A CG 1 ATOM 253 O OD1 . ASP A 1 71 ? -87.363 11.952 -6.575 1.00 128.70 ? 71 ASP A OD1 1 ATOM 254 O OD2 . ASP A 1 71 ? -88.394 13.680 -7.452 1.00 109.77 ? 71 ASP A OD2 1 ATOM 255 N N . ARG A 1 72 ? -84.349 14.278 -9.152 1.00 100.71 ? 72 ARG A N 1 ATOM 256 C CA . ARG A 1 72 ? -84.199 14.287 -10.598 1.00 94.61 ? 72 ARG A CA 1 ATOM 257 C C . ARG A 1 72 ? -82.948 13.538 -11.034 1.00 96.32 ? 72 ARG A C 1 ATOM 258 O O . ARG A 1 72 ? -82.210 12.993 -10.211 1.00 91.24 ? 72 ARG A O 1 ATOM 259 C CB . ARG A 1 72 ? -84.156 15.723 -11.126 1.00 84.56 ? 72 ARG A CB 1 ATOM 260 C CG . ARG A 1 72 ? -85.489 16.448 -11.077 1.00 87.51 ? 72 ARG A CG 1 ATOM 261 C CD . ARG A 1 72 ? -85.401 17.793 -11.776 1.00 90.75 ? 72 ARG A CD 1 ATOM 262 N NE . ARG A 1 72 ? -86.705 18.439 -11.898 1.00 105.15 ? 72 ARG A NE 1 ATOM 263 C CZ . ARG A 1 72 ? -87.524 18.282 -12.934 1.00 106.37 ? 72 ARG A CZ 1 ATOM 264 N NH1 . ARG A 1 72 ? -87.176 17.497 -13.945 1.00 98.29 ? 72 ARG A NH1 1 ATOM 265 N NH2 . ARG A 1 72 ? -88.691 18.910 -12.958 1.00 101.27 ? 72 ARG A NH2 1 ATOM 266 N N . LYS A 1 73 ? -82.722 13.516 -12.341 1.00 93.33 ? 73 LYS A N 1 ATOM 267 C CA . LYS A 1 73 ? -81.518 12.927 -12.903 1.00 77.86 ? 73 LYS A CA 1 ATOM 268 C C . LYS A 1 73 ? -80.447 13.997 -13.054 1.00 82.26 ? 73 LYS A C 1 ATOM 269 O O . LYS A 1 73 ? -79.386 13.749 -13.615 1.00 97.54 ? 73 LYS A O 1 ATOM 270 C CB . LYS A 1 73 ? -81.820 12.254 -14.241 1.00 72.69 ? 73 LYS A CB 1 ATOM 271 C CG . LYS A 1 73 ? -82.612 10.966 -14.091 1.00 85.83 ? 73 LYS A CG 1 ATOM 272 C CD . LYS A 1 73 ? -83.628 10.792 -15.208 1.00 97.69 ? 73 LYS A CD 1 ATOM 273 C CE . LYS A 1 73 ? -84.647 9.715 -14.854 1.00 102.56 ? 73 LYS A CE 1 ATOM 274 N NZ . LYS A 1 73 ? -85.772 9.650 -15.830 1.00 100.85 ? 73 LYS A NZ 1 ATOM 275 N N . HIS A 1 74 ? -80.742 15.194 -12.558 1.00 78.96 ? 74 HIS A N 1 ATOM 276 C CA . HIS A 1 74 ? -79.782 16.293 -12.568 1.00 77.47 ? 74 HIS A CA 1 ATOM 277 C C . HIS A 1 74 ? -78.773 16.144 -11.427 1.00 77.03 ? 74 HIS A C 1 ATOM 278 O O . HIS A 1 74 ? -78.804 15.163 -10.684 1.00 77.20 ? 74 HIS A O 1 ATOM 279 C CB . HIS A 1 74 ? -80.501 17.639 -12.441 1.00 76.34 ? 74 HIS A CB 1 ATOM 280 C CG . HIS A 1 74 ? -81.485 17.909 -13.544 1.00 74.23 ? 74 HIS A CG 1 ATOM 281 N ND1 . HIS A 1 74 ? -81.896 16.948 -14.429 1.00 75.51 ? 74 HIS A ND1 1 ATOM 282 C CD2 . HIS A 1 74 ? -82.131 19.052 -13.885 1.00 71.60 ? 74 HIS A CD2 1 ATOM 283 C CE1 . HIS A 1 74 ? -82.764 17.481 -15.284 1.00 83.06 ? 74 HIS A CE1 1 ATOM 284 N NE2 . HIS A 1 74 ? -82.918 18.749 -14.972 1.00 84.01 ? 74 HIS A NE2 1 ATOM 285 N N . VAL A 1 75 ? -77.884 17.125 -11.294 1.00 72.43 ? 75 VAL A N 1 ATOM 286 C CA . VAL A 1 75 ? -76.878 17.138 -10.231 1.00 76.00 ? 75 VAL A CA 1 ATOM 287 C C . VAL A 1 75 ? -76.675 18.570 -9.730 1.00 74.79 ? 75 VAL A C 1 ATOM 288 O O . VAL A 1 75 ? -76.696 19.514 -10.522 1.00 72.08 ? 75 VAL A O 1 ATOM 289 C CB . VAL A 1 75 ? -75.534 16.517 -10.707 1.00 71.28 ? 75 VAL A CB 1 ATOM 290 C CG1 . VAL A 1 75 ? -74.359 17.053 -9.907 1.00 66.43 ? 75 VAL A CG1 1 ATOM 291 C CG2 . VAL A 1 75 ? -75.580 15.000 -10.614 1.00 70.62 ? 75 VAL A CG2 1 ATOM 292 N N . PHE A 1 76 ? -76.508 18.736 -8.419 1.00 70.98 ? 76 PHE A N 1 ATOM 293 C CA . PHE A 1 76 ? -76.309 20.065 -7.846 1.00 70.66 ? 76 PHE A CA 1 ATOM 294 C C . PHE A 1 76 ? -74.849 20.352 -7.503 1.00 69.86 ? 76 PHE A C 1 ATOM 295 O O . PHE A 1 76 ? -74.105 19.451 -7.122 1.00 69.91 ? 76 PHE A O 1 ATOM 296 C CB . PHE A 1 76 ? -77.204 20.280 -6.613 1.00 74.91 ? 76 PHE A CB 1 ATOM 297 C CG . PHE A 1 76 ? -76.825 19.448 -5.409 1.00 78.37 ? 76 PHE A CG 1 ATOM 298 C CD1 . PHE A 1 76 ? -77.492 18.266 -5.130 1.00 88.47 ? 76 PHE A CD1 1 ATOM 299 C CD2 . PHE A 1 76 ? -75.831 19.868 -4.537 1.00 72.91 ? 76 PHE A CD2 1 ATOM 300 C CE1 . PHE A 1 76 ? -77.161 17.510 -4.015 1.00 88.37 ? 76 PHE A CE1 1 ATOM 301 C CE2 . PHE A 1 76 ? -75.492 19.115 -3.427 1.00 71.86 ? 76 PHE A CE2 1 ATOM 302 C CZ . PHE A 1 76 ? -76.158 17.935 -3.166 1.00 76.31 ? 76 PHE A CZ 1 ATOM 303 N N . LEU A 1 77 ? -74.443 21.610 -7.656 1.00 69.45 ? 77 LEU A N 1 ATOM 304 C CA . LEU A 1 77 ? -73.150 22.064 -7.153 1.00 67.66 ? 77 LEU A CA 1 ATOM 305 C C . LEU A 1 77 ? -73.357 23.043 -6.003 1.00 71.06 ? 77 LEU A C 1 ATOM 306 O O . LEU A 1 77 ? -74.093 24.019 -6.139 1.00 72.28 ? 77 LEU A O 1 ATOM 307 C CB . LEU A 1 77 ? -72.329 22.737 -8.255 1.00 64.70 ? 77 LEU A CB 1 ATOM 308 C CG . LEU A 1 77 ? -71.020 23.380 -7.781 1.00 63.42 ? 77 LEU A CG 1 ATOM 309 C CD1 . LEU A 1 77 ? -70.029 22.319 -7.324 1.00 59.31 ? 77 LEU A CD1 1 ATOM 310 C CD2 . LEU A 1 77 ? -70.405 24.271 -8.854 1.00 61.28 ? 77 LEU A CD2 1 ATOM 311 N N . VAL A 1 78 ? -72.711 22.782 -4.872 1.00 73.81 ? 78 VAL A N 1 ATOM 312 C CA . VAL A 1 78 ? -72.788 23.693 -3.734 1.00 75.30 ? 78 VAL A CA 1 ATOM 313 C C . VAL A 1 78 ? -71.399 24.139 -3.274 1.00 77.14 ? 78 VAL A C 1 ATOM 314 O O . VAL A 1 78 ? -70.594 23.330 -2.810 1.00 67.92 ? 78 VAL A O 1 ATOM 315 C CB . VAL A 1 78 ? -73.565 23.071 -2.557 1.00 73.69 ? 78 VAL A CB 1 ATOM 316 C CG1 . VAL A 1 78 ? -73.481 23.963 -1.334 1.00 74.41 ? 78 VAL A CG1 1 ATOM 317 C CG2 . VAL A 1 78 ? -75.013 22.852 -2.947 1.00 69.33 ? 78 VAL A CG2 1 ATOM 318 N N . ILE A 1 79 ? -71.130 25.434 -3.412 1.00 77.22 ? 79 ILE A N 1 ATOM 319 C CA . ILE A 1 79 ? -69.852 26.008 -3.012 1.00 73.86 ? 79 ILE A CA 1 ATOM 320 C C . ILE A 1 79 ? -70.038 26.705 -1.670 1.00 71.91 ? 79 ILE A C 1 ATOM 321 O O . ILE A 1 79 ? -70.680 27.752 -1.592 1.00 70.35 ? 79 ILE A O 1 ATOM 322 C CB . ILE A 1 79 ? -69.347 27.034 -4.054 1.00 79.08 ? 79 ILE A CB 1 ATOM 323 C CG1 . ILE A 1 79 ? -69.485 26.479 -5.475 1.00 65.52 ? 79 ILE A CG1 1 ATOM 324 C CG2 . ILE A 1 79 ? -67.906 27.437 -3.764 1.00 84.89 ? 79 ILE A CG2 1 ATOM 325 C CD1 . ILE A 1 79 ? -69.290 27.520 -6.566 1.00 52.77 ? 79 ILE A CD1 1 ATOM 326 N N . VAL A 1 80 ? -69.470 26.124 -0.618 1.00 79.04 ? 80 VAL A N 1 ATOM 327 C CA . VAL A 1 80 ? -69.670 26.629 0.737 1.00 80.90 ? 80 VAL A CA 1 ATOM 328 C C . VAL A 1 80 ? -68.475 27.425 1.243 1.00 82.83 ? 80 VAL A C 1 ATOM 329 O O . VAL A 1 80 ? -67.406 26.865 1.492 1.00 85.35 ? 80 VAL A O 1 ATOM 330 C CB . VAL A 1 80 ? -69.941 25.482 1.734 1.00 78.79 ? 80 VAL A CB 1 ATOM 331 C CG1 . VAL A 1 80 ? -70.084 26.026 3.142 1.00 82.16 ? 80 VAL A CG1 1 ATOM 332 C CG2 . VAL A 1 80 ? -71.186 24.715 1.337 1.00 82.54 ? 80 VAL A CG2 1 ATOM 333 N N . LYS A 1 81 ? -68.660 28.731 1.401 1.00 85.08 ? 81 LYS A N 1 ATOM 334 C CA . LYS A 1 81 ? -67.656 29.549 2.063 1.00 92.02 ? 81 LYS A CA 1 ATOM 335 C C . LYS A 1 81 ? -68.143 29.866 3.467 1.00 99.73 ? 81 LYS A C 1 ATOM 336 O O . LYS A 1 81 ? -69.050 30.676 3.656 1.00 106.91 ? 81 LYS A O 1 ATOM 337 C CB . LYS A 1 81 ? -67.408 30.847 1.289 1.00 93.17 ? 81 LYS A CB 1 ATOM 338 C CG . LYS A 1 81 ? -66.864 30.644 -0.118 1.00 99.18 ? 81 LYS A CG 1 ATOM 339 C CD . LYS A 1 81 ? -66.320 31.943 -0.695 1.00 96.68 ? 81 LYS A CD 1 ATOM 340 C CE . LYS A 1 81 ? -65.606 31.704 -2.016 1.00 79.38 ? 81 LYS A CE 1 ATOM 341 N NZ . LYS A 1 81 ? -64.910 32.929 -2.498 1.00 72.30 ? 81 LYS A NZ 1 ATOM 342 N N . VAL A 1 82 ? -67.532 29.218 4.452 1.00 97.08 ? 82 VAL A N 1 ATOM 343 C CA . VAL A 1 82 ? -67.844 29.476 5.849 1.00 95.61 ? 82 VAL A CA 1 ATOM 344 C C . VAL A 1 82 ? -66.559 29.549 6.654 1.00 105.35 ? 82 VAL A C 1 ATOM 345 O O . VAL A 1 82 ? -65.776 28.600 6.678 1.00 110.69 ? 82 VAL A O 1 ATOM 346 C CB . VAL A 1 82 ? -68.784 28.403 6.454 1.00 88.75 ? 82 VAL A CB 1 ATOM 347 C CG1 . VAL A 1 82 ? -70.216 28.631 6.001 1.00 95.97 ? 82 VAL A CG1 1 ATOM 348 C CG2 . VAL A 1 82 ? -68.316 26.995 6.095 1.00 85.15 ? 82 VAL A CG2 1 ATOM 349 N N . ASN A 1 83 ? -66.329 30.685 7.298 1.00 108.59 ? 83 ASN A N 1 ATOM 350 C CA . ASN A 1 83 ? -65.177 30.817 8.171 1.00 116.68 ? 83 ASN A CA 1 ATOM 351 C C . ASN A 1 83 ? -65.387 29.944 9.405 1.00 118.12 ? 83 ASN A C 1 ATOM 352 O O . ASN A 1 83 ? -66.359 30.127 10.139 1.00 115.00 ? 83 ASN A O 1 ATOM 353 C CB . ASN A 1 83 ? -64.963 32.281 8.562 1.00 116.41 ? 83 ASN A CB 1 ATOM 354 C CG . ASN A 1 83 ? -63.511 32.599 8.880 1.00 108.33 ? 83 ASN A CG 1 ATOM 355 O OD1 . ASN A 1 83 ? -62.605 31.840 8.536 1.00 101.64 ? 83 ASN A OD1 1 ATOM 356 N ND2 . ASN A 1 83 ? -63.285 33.733 9.531 1.00 112.00 ? 83 ASN A ND2 1 ATOM 357 N N . PRO A 1 84 ? -64.469 28.991 9.639 1.00 120.84 ? 84 PRO A N 1 ATOM 358 C CA . PRO A 1 84 ? -64.478 28.033 10.755 1.00 122.80 ? 84 PRO A CA 1 ATOM 359 C C . PRO A 1 84 ? -64.496 28.733 12.112 1.00 127.24 ? 84 PRO A C 1 ATOM 360 O O . PRO A 1 84 ? -64.714 28.100 13.145 1.00 129.80 ? 84 PRO A O 1 ATOM 361 C CB . PRO A 1 84 ? -63.173 27.259 10.559 1.00 131.34 ? 84 PRO A CB 1 ATOM 362 C CG . PRO A 1 84 ? -62.915 27.344 9.097 1.00 117.29 ? 84 PRO A CG 1 ATOM 363 C CD . PRO A 1 84 ? -63.353 28.727 8.713 1.00 114.06 ? 84 PRO A CD 1 ATOM 364 N N . THR A 1 85 ? -64.279 30.043 12.086 1.00 126.12 ? 85 THR A N 1 ATOM 365 C CA . THR A 1 85 ? -64.261 30.886 13.272 1.00 126.80 ? 85 THR A CA 1 ATOM 366 C C . THR A 1 85 ? -65.693 31.193 13.694 1.00 125.34 ? 85 THR A C 1 ATOM 367 O O . THR A 1 85 ? -65.931 32.048 14.548 1.00 130.68 ? 85 THR A O 1 ATOM 368 C CB . THR A 1 85 ? -63.503 32.171 12.992 1.00 122.35 ? 85 THR A CB 1 ATOM 369 N N . THR A 1 86 ? -66.633 30.509 13.043 1.00 120.29 ? 86 THR A N 1 ATOM 370 C CA . THR A 1 86 ? -68.069 30.624 13.292 1.00 128.64 ? 86 THR A CA 1 ATOM 371 C C . THR A 1 86 ? -68.629 31.967 12.851 1.00 130.48 ? 86 THR A C 1 ATOM 372 O O . THR A 1 86 ? -69.530 32.523 13.480 1.00 136.78 ? 86 THR A O 1 ATOM 373 C CB . THR A 1 86 ? -68.404 30.339 14.759 1.00 130.82 ? 86 THR A CB 1 ATOM 374 N N . HIS A 1 87 ? -68.094 32.466 11.744 1.00 120.87 ? 87 HIS A N 1 ATOM 375 C CA . HIS A 1 87 ? -68.685 33.595 11.050 1.00 119.49 ? 87 HIS A CA 1 ATOM 376 C C . HIS A 1 87 ? -69.819 33.063 10.181 1.00 120.04 ? 87 HIS A C 1 ATOM 377 O O . HIS A 1 87 ? -70.168 31.885 10.259 1.00 113.46 ? 87 HIS A O 1 ATOM 378 C CB . HIS A 1 87 ? -67.644 34.297 10.203 1.00 113.92 ? 87 HIS A CB 1 ATOM 379 N N . GLU A 1 88 ? -70.393 33.926 9.351 1.00 121.25 ? 88 GLU A N 1 ATOM 380 C CA . GLU A 1 88 ? -71.489 33.514 8.484 1.00 113.40 ? 88 GLU A CA 1 ATOM 381 C C . GLU A 1 88 ? -70.986 33.124 7.099 1.00 112.64 ? 88 GLU A C 1 ATOM 382 O O . GLU A 1 88 ? -71.043 31.957 6.712 1.00 108.42 ? 88 GLU A O 1 ATOM 383 C CB . GLU A 1 88 ? -72.528 34.619 8.382 1.00 111.61 ? 88 GLU A CB 1 ATOM 384 N N . GLY A 1 89 ? -70.486 34.108 6.360 1.00 115.66 ? 89 GLY A N 1 ATOM 385 C CA . GLY A 1 89 ? -70.074 33.886 4.988 1.00 113.27 ? 89 GLY A CA 1 ATOM 386 C C . GLY A 1 89 ? -71.281 33.682 4.094 1.00 105.13 ? 89 GLY A C 1 ATOM 387 O O . GLY A 1 89 ? -72.359 34.215 4.363 1.00 105.88 ? 89 GLY A O 1 ATOM 388 N N . ASP A 1 90 ? -71.105 32.905 3.032 1.00 96.63 ? 90 ASP A N 1 ATOM 389 C CA . ASP A 1 90 ? -72.191 32.642 2.098 1.00 91.57 ? 90 ASP A CA 1 ATOM 390 C C . ASP A 1 90 ? -71.980 31.338 1.341 1.00 87.90 ? 90 ASP A C 1 ATOM 391 O O . ASP A 1 90 ? -70.869 30.812 1.289 1.00 94.74 ? 90 ASP A O 1 ATOM 392 C CB . ASP A 1 90 ? -72.346 33.806 1.114 1.00 96.70 ? 90 ASP A CB 1 ATOM 393 C CG . ASP A 1 90 ? -71.013 34.318 0.597 1.00 117.17 ? 90 ASP A CG 1 ATOM 394 O OD1 . ASP A 1 90 ? -70.013 33.571 0.666 1.00 121.33 ? 90 ASP A OD1 1 ATOM 395 O OD2 . ASP A 1 90 ? -70.964 35.471 0.117 1.00 122.51 ? 90 ASP A OD2 1 ATOM 396 N N . VAL A 1 91 ? -73.056 30.819 0.761 1.00 80.38 ? 91 VAL A N 1 ATOM 397 C CA . VAL A 1 91 ? -72.974 29.646 -0.100 1.00 81.24 ? 91 VAL A CA 1 ATOM 398 C C . VAL A 1 91 ? -73.716 29.940 -1.396 1.00 84.05 ? 91 VAL A C 1 ATOM 399 O O . VAL A 1 91 ? -74.425 30.941 -1.500 1.00 85.13 ? 91 VAL A O 1 ATOM 400 C CB . VAL A 1 91 ? -73.571 28.379 0.559 1.00 68.57 ? 91 VAL A CB 1 ATOM 401 C CG1 . VAL A 1 91 ? -72.927 28.118 1.913 1.00 76.42 ? 91 VAL A CG1 1 ATOM 402 C CG2 . VAL A 1 91 ? -75.070 28.506 0.700 1.00 63.12 ? 91 VAL A CG2 1 ATOM 403 N N . GLY A 1 92 ? -73.546 29.073 -2.386 1.00 85.19 ? 92 GLY A N 1 ATOM 404 C CA . GLY A 1 92 ? -74.224 29.247 -3.654 1.00 74.12 ? 92 GLY A CA 1 ATOM 405 C C . GLY A 1 92 ? -74.524 27.905 -4.282 1.00 69.52 ? 92 GLY A C 1 ATOM 406 O O . GLY A 1 92 ? -73.870 26.907 -3.978 1.00 64.55 ? 92 GLY A O 1 ATOM 407 N N . LEU A 1 93 ? -75.514 27.883 -5.166 1.00 74.25 ? 93 LEU A N 1 ATOM 408 C CA . LEU A 1 93 ? -75.963 26.638 -5.772 1.00 80.87 ? 93 LEU A CA 1 ATOM 409 C C . LEU A 1 93 ? -76.258 26.792 -7.254 1.00 88.85 ? 93 LEU A C 1 ATOM 410 O O . LEU A 1 93 ? -76.883 27.764 -7.680 1.00 97.33 ? 93 LEU A O 1 ATOM 411 C CB . LEU A 1 93 ? -77.220 26.115 -5.073 1.00 80.39 ? 93 LEU A CB 1 ATOM 412 C CG . LEU A 1 93 ? -78.008 25.096 -5.903 1.00 77.57 ? 93 LEU A CG 1 ATOM 413 C CD1 . LEU A 1 93 ? -77.805 23.674 -5.397 1.00 76.34 ? 93 LEU A CD1 1 ATOM 414 C CD2 . LEU A 1 93 ? -79.484 25.457 -5.982 1.00 84.29 ? 93 LEU A CD2 1 ATOM 415 N N . VAL A 1 94 ? -75.802 25.821 -8.036 1.00 79.97 ? 94 VAL A N 1 ATOM 416 C CA . VAL A 1 94 ? -76.223 25.697 -9.421 1.00 75.02 ? 94 VAL A CA 1 ATOM 417 C C . VAL A 1 94 ? -76.637 24.252 -9.708 1.00 73.01 ? 94 VAL A C 1 ATOM 418 O O . VAL A 1 94 ? -75.832 23.328 -9.588 1.00 69.08 ? 94 VAL A O 1 ATOM 419 C CB . VAL A 1 94 ? -75.125 26.183 -10.396 1.00 70.78 ? 94 VAL A CB 1 ATOM 420 C CG1 . VAL A 1 94 ? -73.745 25.790 -9.895 1.00 72.44 ? 94 VAL A CG1 1 ATOM 421 C CG2 . VAL A 1 94 ? -75.377 25.662 -11.803 1.00 77.56 ? 94 VAL A CG2 1 ATOM 422 N N . ILE A 1 95 ? -77.908 24.061 -10.053 1.00 75.30 ? 95 ILE A N 1 ATOM 423 C CA . ILE A 1 95 ? -78.397 22.748 -10.459 1.00 74.01 ? 95 ILE A CA 1 ATOM 424 C C . ILE A 1 95 ? -78.283 22.622 -11.973 1.00 76.16 ? 95 ILE A C 1 ATOM 425 O O . ILE A 1 95 ? -78.958 23.337 -12.716 1.00 79.75 ? 95 ILE A O 1 ATOM 426 C CB . ILE A 1 95 ? -79.867 22.516 -10.042 1.00 83.03 ? 95 ILE A CB 1 ATOM 427 C CG1 . ILE A 1 95 ? -80.031 22.613 -8.522 1.00 83.13 ? 95 ILE A CG1 1 ATOM 428 C CG2 . ILE A 1 95 ? -80.349 21.162 -10.536 1.00 87.16 ? 95 ILE A CG2 1 ATOM 429 C CD1 . ILE A 1 95 ? -81.461 22.387 -8.037 1.00 73.26 ? 95 ILE A CD1 1 ATOM 430 N N . PHE A 1 96 ? -77.422 21.714 -12.424 1.00 75.61 ? 96 PHE A N 1 ATOM 431 C CA . PHE A 1 96 ? -77.191 21.504 -13.851 1.00 74.97 ? 96 PHE A CA 1 ATOM 432 C C . PHE A 1 96 ? -77.630 20.100 -14.267 1.00 74.58 ? 96 PHE A C 1 ATOM 433 O O . PHE A 1 96 ? -77.627 19.182 -13.446 1.00 73.71 ? 96 PHE A O 1 ATOM 434 C CB . PHE A 1 96 ? -75.718 21.764 -14.211 1.00 69.29 ? 96 PHE A CB 1 ATOM 435 C CG . PHE A 1 96 ? -74.736 20.884 -13.480 1.00 67.68 ? 96 PHE A CG 1 ATOM 436 C CD1 . PHE A 1 96 ? -74.253 19.725 -14.068 1.00 65.49 ? 96 PHE A CD1 1 ATOM 437 C CD2 . PHE A 1 96 ? -74.277 21.230 -12.219 1.00 67.39 ? 96 PHE A CD2 1 ATOM 438 C CE1 . PHE A 1 96 ? -73.344 18.920 -13.405 1.00 58.89 ? 96 PHE A CE1 1 ATOM 439 C CE2 . PHE A 1 96 ? -73.368 20.429 -11.552 1.00 62.35 ? 96 PHE A CE2 1 ATOM 440 C CZ . PHE A 1 96 ? -72.900 19.274 -12.147 1.00 57.29 ? 96 PHE A CZ 1 ATOM 441 N N . PRO A 1 97 ? -78.025 19.930 -15.542 1.00 66.67 ? 97 PRO A N 1 ATOM 442 C CA . PRO A 1 97 ? -78.535 18.629 -15.989 1.00 67.87 ? 97 PRO A CA 1 ATOM 443 C C . PRO A 1 97 ? -77.455 17.555 -16.035 1.00 68.75 ? 97 PRO A C 1 ATOM 444 O O . PRO A 1 97 ? -76.288 17.835 -15.768 1.00 72.84 ? 97 PRO A O 1 ATOM 445 C CB . PRO A 1 97 ? -79.046 18.924 -17.401 1.00 70.69 ? 97 PRO A CB 1 ATOM 446 C CG . PRO A 1 97 ? -78.249 20.095 -17.852 1.00 67.33 ? 97 PRO A CG 1 ATOM 447 C CD . PRO A 1 97 ? -78.060 20.932 -16.623 1.00 62.07 ? 97 PRO A CD 1 ATOM 448 N N . LYS A 1 98 ? -77.852 16.337 -16.384 1.00 73.02 ? 98 LYS A N 1 ATOM 449 C CA . LYS A 1 98 ? -76.947 15.195 -16.352 1.00 80.29 ? 98 LYS A CA 1 ATOM 450 C C . LYS A 1 98 ? -75.991 15.121 -17.541 1.00 83.81 ? 98 LYS A C 1 ATOM 451 O O . LYS A 1 98 ? -74.786 14.918 -17.369 1.00 77.12 ? 98 LYS A O 1 ATOM 452 C CB . LYS A 1 98 ? -77.755 13.901 -16.266 1.00 80.95 ? 98 LYS A CB 1 ATOM 453 C CG . LYS A 1 98 ? -76.908 12.652 -16.232 1.00 77.76 ? 98 LYS A CG 1 ATOM 454 C CD . LYS A 1 98 ? -75.858 12.692 -15.133 1.00 75.98 ? 98 LYS A CD 1 ATOM 455 C CE . LYS A 1 98 ? -76.473 12.570 -13.752 1.00 72.91 ? 98 LYS A CE 1 ATOM 456 N NZ . LYS A 1 98 ? -77.014 13.851 -13.231 1.00 81.06 ? 98 LYS A NZ 1 ATOM 457 N N . TYR A 1 99 ? -76.538 15.293 -18.741 1.00 88.86 ? 99 TYR A N 1 ATOM 458 C CA . TYR A 1 99 ? -75.801 15.068 -19.984 1.00 87.03 ? 99 TYR A CA 1 ATOM 459 C C . TYR A 1 99 ? -74.541 15.923 -20.120 1.00 80.62 ? 99 TYR A C 1 ATOM 460 O O . TYR A 1 99 ? -73.647 15.598 -20.901 1.00 86.99 ? 99 TYR A O 1 ATOM 461 C CB . TYR A 1 99 ? -76.719 15.266 -21.197 1.00 86.71 ? 99 TYR A CB 1 ATOM 462 C CG . TYR A 1 99 ? -77.365 16.633 -21.277 1.00 84.57 ? 99 TYR A CG 1 ATOM 463 C CD1 . TYR A 1 99 ? -76.749 17.673 -21.961 1.00 85.82 ? 99 TYR A CD1 1 ATOM 464 C CD2 . TYR A 1 99 ? -78.593 16.881 -20.678 1.00 82.43 ? 99 TYR A CD2 1 ATOM 465 C CE1 . TYR A 1 99 ? -77.334 18.923 -22.039 1.00 84.25 ? 99 TYR A CE1 1 ATOM 466 C CE2 . TYR A 1 99 ? -79.185 18.129 -20.753 1.00 86.16 ? 99 TYR A CE2 1 ATOM 467 C CZ . TYR A 1 99 ? -78.550 19.146 -21.433 1.00 86.80 ? 99 TYR A CZ 1 ATOM 468 O OH . TYR A 1 99 ? -79.131 20.392 -21.511 1.00 84.75 ? 99 TYR A OH 1 ATOM 469 N N . LEU A 1 100 ? -74.473 17.006 -19.352 1.00 67.87 ? 100 LEU A N 1 ATOM 470 C CA . LEU A 1 100 ? -73.320 17.898 -19.379 1.00 65.52 ? 100 LEU A CA 1 ATOM 471 C C . LEU A 1 100 ? -72.027 17.179 -18.994 1.00 70.99 ? 100 LEU A C 1 ATOM 472 O O . LEU A 1 100 ? -70.940 17.591 -19.394 1.00 71.59 ? 100 LEU A O 1 ATOM 473 C CB . LEU A 1 100 ? -73.555 19.104 -18.465 1.00 56.41 ? 100 LEU A CB 1 ATOM 474 C CG . LEU A 1 100 ? -73.665 20.467 -19.154 1.00 52.35 ? 100 LEU A CG 1 ATOM 475 C CD1 . LEU A 1 100 ? -74.767 20.460 -20.192 1.00 60.18 ? 100 LEU A CD1 1 ATOM 476 C CD2 . LEU A 1 100 ? -73.908 21.567 -18.138 1.00 61.07 ? 100 LEU A CD2 1 ATOM 477 N N . LEU A 1 101 ? -72.150 16.103 -18.221 1.00 71.11 ? 101 LEU A N 1 ATOM 478 C CA . LEU A 1 101 ? -70.984 15.329 -17.798 1.00 72.19 ? 101 LEU A CA 1 ATOM 479 C C . LEU A 1 101 ? -70.446 14.397 -18.890 1.00 76.48 ? 101 LEU A C 1 ATOM 480 O O . LEU A 1 101 ? -69.239 14.341 -19.127 1.00 78.03 ? 101 LEU A O 1 ATOM 481 C CB . LEU A 1 101 ? -71.288 14.538 -16.521 1.00 64.80 ? 101 LEU A CB 1 ATOM 482 C CG . LEU A 1 101 ? -71.603 15.350 -15.263 1.00 56.71 ? 101 LEU A CG 1 ATOM 483 C CD1 . LEU A 1 101 ? -71.482 14.486 -14.018 1.00 55.85 ? 101 LEU A CD1 1 ATOM 484 C CD2 . LEU A 1 101 ? -70.696 16.561 -15.162 1.00 54.80 ? 101 LEU A CD2 1 ATOM 485 N N . SER A 1 102 ? -71.341 13.667 -19.548 1.00 78.18 ? 102 SER A N 1 ATOM 486 C CA . SER A 1 102 ? -70.942 12.713 -20.580 1.00 80.26 ? 102 SER A CA 1 ATOM 487 C C . SER A 1 102 ? -70.424 13.446 -21.815 1.00 79.05 ? 102 SER A C 1 ATOM 488 O O . SER A 1 102 ? -70.929 14.513 -22.160 1.00 77.48 ? 102 SER A O 1 ATOM 489 C CB . SER A 1 102 ? -72.122 11.810 -20.950 1.00 87.47 ? 102 SER A CB 1 ATOM 490 O OG . SER A 1 102 ? -71.677 10.548 -21.421 1.00 85.30 ? 102 SER A OG 1 ATOM 491 N N . PRO A 1 103 ? -69.408 12.877 -22.484 1.00 79.05 ? 103 PRO A N 1 ATOM 492 C CA . PRO A 1 103 ? -68.786 13.521 -23.646 1.00 78.56 ? 103 PRO A CA 1 ATOM 493 C C . PRO A 1 103 ? -69.692 13.529 -24.874 1.00 88.96 ? 103 PRO A C 1 ATOM 494 O O . PRO A 1 103 ? -70.654 12.763 -24.933 1.00 99.59 ? 103 PRO A O 1 ATOM 495 C CB . PRO A 1 103 ? -67.562 12.643 -23.910 1.00 87.70 ? 103 PRO A CB 1 ATOM 496 C CG . PRO A 1 103 ? -67.954 11.302 -23.393 1.00 88.25 ? 103 PRO A CG 1 ATOM 497 C CD . PRO A 1 103 ? -68.777 11.583 -22.170 1.00 84.49 ? 103 PRO A CD 1 ATOM 498 N N . TYR A 1 104 ? -69.380 14.387 -25.841 1.00 88.82 ? 104 TYR A N 1 ATOM 499 C CA . TYR A 1 104 ? -70.167 14.487 -27.066 1.00 94.68 ? 104 TYR A CA 1 ATOM 500 C C . TYR A 1 104 ? -69.808 13.374 -28.046 1.00 94.37 ? 104 TYR A C 1 ATOM 501 O O . TYR A 1 104 ? -70.329 13.323 -29.160 1.00 85.91 ? 104 TYR A O 1 ATOM 502 C CB . TYR A 1 104 ? -69.971 15.850 -27.715 1.00 84.75 ? 104 TYR A CB 1 ATOM 503 N N . PHE A 1 119 ? -48.390 2.972 -43.357 1.00 58.98 ? 119 PHE A N 1 ATOM 504 C CA . PHE A 1 119 ? -49.654 2.891 -42.631 1.00 69.80 ? 119 PHE A CA 1 ATOM 505 C C . PHE A 1 119 ? -50.166 4.273 -42.242 1.00 75.19 ? 119 PHE A C 1 ATOM 506 O O . PHE A 1 119 ? -49.518 5.285 -42.513 1.00 75.28 ? 119 PHE A O 1 ATOM 507 C CB . PHE A 1 119 ? -49.507 2.018 -41.401 1.00 60.47 ? 119 PHE A CB 1 ATOM 508 N N . GLY A 1 120 ? -51.323 4.309 -41.586 1.00 70.08 ? 120 GLY A N 1 ATOM 509 C CA . GLY A 1 120 ? -51.961 5.569 -41.258 1.00 72.33 ? 120 GLY A CA 1 ATOM 510 C C . GLY A 1 120 ? -52.730 5.561 -39.952 1.00 74.71 ? 120 GLY A C 1 ATOM 511 O O . GLY A 1 120 ? -52.972 4.509 -39.360 1.00 74.10 ? 120 GLY A O 1 ATOM 512 N N . PHE A 1 121 ? -53.117 6.754 -39.511 1.00 79.53 ? 121 PHE A N 1 ATOM 513 C CA . PHE A 1 121 ? -53.751 6.957 -38.210 1.00 86.19 ? 121 PHE A CA 1 ATOM 514 C C . PHE A 1 121 ? -55.279 6.939 -38.294 1.00 89.53 ? 121 PHE A C 1 ATOM 515 O O . PHE A 1 121 ? -55.969 7.254 -37.323 1.00 90.24 ? 121 PHE A O 1 ATOM 516 C CB . PHE A 1 121 ? -53.244 8.248 -37.554 1.00 80.86 ? 121 PHE A CB 1 ATOM 517 C CG . PHE A 1 121 ? -51.746 8.286 -37.363 1.00 71.49 ? 121 PHE A CG 1 ATOM 518 C CD1 . PHE A 1 121 ? -51.073 9.494 -37.271 1.00 70.57 ? 121 PHE A CD1 1 ATOM 519 C CD2 . PHE A 1 121 ? -51.012 7.111 -37.276 1.00 63.34 ? 121 PHE A CD2 1 ATOM 520 C CE1 . PHE A 1 121 ? -49.697 9.530 -37.099 1.00 63.85 ? 121 PHE A CE1 1 ATOM 521 C CE2 . PHE A 1 121 ? -49.637 7.142 -37.106 1.00 51.64 ? 121 PHE A CE2 1 ATOM 522 C CZ . PHE A 1 121 ? -48.979 8.352 -37.017 1.00 47.13 ? 121 PHE A CZ 1 ATOM 523 N N . LEU A 1 122 ? -55.795 6.575 -39.465 1.00 91.03 ? 122 LEU A N 1 ATOM 524 C CA . LEU A 1 122 ? -57.224 6.653 -39.754 1.00 96.53 ? 122 LEU A CA 1 ATOM 525 C C . LEU A 1 122 ? -58.041 5.604 -38.996 1.00 85.89 ? 122 LEU A C 1 ATOM 526 O O . LEU A 1 122 ? -58.823 5.944 -38.106 1.00 73.51 ? 122 LEU A O 1 ATOM 527 C CB . LEU A 1 122 ? -57.454 6.476 -41.259 1.00 95.15 ? 122 LEU A CB 1 ATOM 528 C CG . LEU A 1 122 ? -56.441 7.114 -42.215 1.00 79.36 ? 122 LEU A CG 1 ATOM 529 C CD1 . LEU A 1 122 ? -56.659 6.619 -43.636 1.00 61.73 ? 122 LEU A CD1 1 ATOM 530 C CD2 . LEU A 1 122 ? -56.518 8.631 -42.161 1.00 75.75 ? 122 LEU A CD2 1 ATOM 531 N N . SER A 1 123 ? -57.858 4.333 -39.348 1.00 86.54 ? 123 SER A N 1 ATOM 532 C CA . SER A 1 123 ? -58.650 3.250 -38.762 1.00 79.95 ? 123 SER A CA 1 ATOM 533 C C . SER A 1 123 ? -58.321 3.003 -37.288 1.00 78.85 ? 123 SER A C 1 ATOM 534 O O . SER A 1 123 ? -59.218 2.750 -36.483 1.00 69.82 ? 123 SER A O 1 ATOM 535 C CB . SER A 1 123 ? -58.496 1.959 -39.570 1.00 68.28 ? 123 SER A CB 1 ATOM 536 O OG . SER A 1 123 ? -57.194 1.420 -39.440 1.00 62.46 ? 123 SER A OG 1 ATOM 537 N N . HIS A 1 124 ? -57.040 3.074 -36.934 1.00 80.78 ? 124 HIS A N 1 ATOM 538 C CA . HIS A 1 124 ? -56.652 2.996 -35.530 1.00 74.73 ? 124 HIS A CA 1 ATOM 539 C C . HIS A 1 124 ? -56.090 4.337 -35.063 1.00 70.61 ? 124 HIS A C 1 ATOM 540 O O . HIS A 1 124 ? -54.955 4.689 -35.387 1.00 62.08 ? 124 HIS A O 1 ATOM 541 C CB . HIS A 1 124 ? -55.610 1.894 -35.316 1.00 65.92 ? 124 HIS A CB 1 ATOM 542 C CG . HIS A 1 124 ? -56.148 0.505 -35.473 1.00 64.58 ? 124 HIS A CG 1 ATOM 543 N ND1 . HIS A 1 124 ? -57.497 0.228 -35.540 1.00 68.12 ? 124 HIS A ND1 1 ATOM 544 C CD2 . HIS A 1 124 ? -55.515 -0.688 -35.572 1.00 56.78 ? 124 HIS A CD2 1 ATOM 545 C CE1 . HIS A 1 124 ? -57.671 -1.074 -35.676 1.00 68.01 ? 124 HIS A CE1 1 ATOM 546 N NE2 . HIS A 1 124 ? -56.484 -1.653 -35.698 1.00 61.83 ? 124 HIS A NE2 1 ATOM 547 N N . PRO A 1 125 ? -56.893 5.090 -34.297 1.00 70.72 ? 125 PRO A N 1 ATOM 548 C CA . PRO A 1 125 ? -56.479 6.373 -33.726 1.00 59.05 ? 125 PRO A CA 1 ATOM 549 C C . PRO A 1 125 ? -55.963 6.254 -32.299 1.00 48.89 ? 125 PRO A C 1 ATOM 550 O O . PRO A 1 125 ? -55.921 5.163 -31.731 1.00 47.99 ? 125 PRO A O 1 ATOM 551 C CB . PRO A 1 125 ? -57.777 7.185 -33.742 1.00 65.35 ? 125 PRO A CB 1 ATOM 552 C CG . PRO A 1 125 ? -58.896 6.154 -33.728 1.00 66.36 ? 125 PRO A CG 1 ATOM 553 C CD . PRO A 1 125 ? -58.299 4.788 -33.981 1.00 68.80 ? 125 PRO A CD 1 ATOM 554 N N . VAL A 1 126 ? -55.571 7.389 -31.733 1.00 46.30 ? 126 VAL A N 1 ATOM 555 C CA . VAL A 1 126 ? -55.359 7.505 -30.298 1.00 41.52 ? 126 VAL A CA 1 ATOM 556 C C . VAL A 1 126 ? -56.243 8.650 -29.822 1.00 42.62 ? 126 VAL A C 1 ATOM 557 O O . VAL A 1 126 ? -56.056 9.799 -30.225 1.00 42.11 ? 126 VAL A O 1 ATOM 558 C CB . VAL A 1 126 ? -53.882 7.766 -29.940 1.00 33.13 ? 126 VAL A CB 1 ATOM 559 C CG1 . VAL A 1 126 ? -53.759 8.241 -28.507 1.00 31.54 ? 126 VAL A CG1 1 ATOM 560 C CG2 . VAL A 1 126 ? -53.062 6.506 -30.141 1.00 30.90 ? 126 VAL A CG2 1 ATOM 561 N N . THR A 1 127 ? -57.222 8.329 -28.984 1.00 43.31 ? 127 THR A N 1 ATOM 562 C CA . THR A 1 127 ? -58.221 9.311 -28.576 1.00 42.63 ? 127 THR A CA 1 ATOM 563 C C . THR A 1 127 ? -58.024 9.794 -27.143 1.00 42.99 ? 127 THR A C 1 ATOM 564 O O . THR A 1 127 ? -58.019 8.995 -26.205 1.00 40.88 ? 127 THR A O 1 ATOM 565 C CB . THR A 1 127 ? -59.656 8.765 -28.747 1.00 44.06 ? 127 THR A CB 1 ATOM 566 O OG1 . THR A 1 127 ? -59.754 7.468 -28.148 1.00 46.70 ? 127 THR A OG1 1 ATOM 567 C CG2 . THR A 1 127 ? -60.009 8.657 -30.222 1.00 52.72 ? 127 THR A CG2 1 ATOM 568 N N . PRO A 1 128 ? -57.848 11.113 -26.975 1.00 44.16 ? 128 PRO A N 1 ATOM 569 C CA . PRO A 1 128 ? -57.747 11.720 -25.646 1.00 47.11 ? 128 PRO A CA 1 ATOM 570 C C . PRO A 1 128 ? -59.124 11.776 -25.007 1.00 48.64 ? 128 PRO A C 1 ATOM 571 O O . PRO A 1 128 ? -60.110 11.940 -25.726 1.00 44.13 ? 128 PRO A O 1 ATOM 572 C CB . PRO A 1 128 ? -57.271 13.149 -25.943 1.00 46.27 ? 128 PRO A CB 1 ATOM 573 C CG . PRO A 1 128 ? -56.859 13.158 -27.387 1.00 40.83 ? 128 PRO A CG 1 ATOM 574 C CD . PRO A 1 128 ? -57.689 12.110 -28.046 1.00 42.45 ? 128 PRO A CD 1 ATOM 575 N N . ASP A 1 129 ? -59.199 11.646 -23.687 1.00 46.66 ? 129 ASP A N 1 ATOM 576 C CA . ASP A 1 129 ? -60.481 11.762 -23.001 1.00 47.23 ? 129 ASP A CA 1 ATOM 577 C C . ASP A 1 129 ? -60.634 13.131 -22.348 1.00 47.52 ? 129 ASP A C 1 ATOM 578 O O . ASP A 1 129 ? -59.662 13.714 -21.866 1.00 47.18 ? 129 ASP A O 1 ATOM 579 C CB . ASP A 1 129 ? -60.670 10.637 -21.980 1.00 40.98 ? 129 ASP A CB 1 ATOM 580 C CG . ASP A 1 129 ? -61.241 9.376 -22.603 1.00 45.41 ? 129 ASP A CG 1 ATOM 581 O OD1 . ASP A 1 129 ? -62.056 9.487 -23.542 1.00 56.32 ? 129 ASP A OD1 1 ATOM 582 O OD2 . ASP A 1 129 ? -60.880 8.270 -22.151 1.00 43.66 ? 129 ASP A OD2 1 ATOM 583 N N . VAL A 1 130 ? -61.863 13.639 -22.357 1.00 49.75 ? 130 VAL A N 1 ATOM 584 C CA . VAL A 1 130 ? -62.165 14.970 -21.845 1.00 49.21 ? 130 VAL A CA 1 ATOM 585 C C . VAL A 1 130 ? -61.807 15.069 -20.372 1.00 48.51 ? 130 VAL A C 1 ATOM 586 O O . VAL A 1 130 ? -61.018 15.922 -19.964 1.00 48.78 ? 130 VAL A O 1 ATOM 587 C CB . VAL A 1 130 ? -63.667 15.282 -21.981 1.00 54.96 ? 130 VAL A CB 1 ATOM 588 C CG1 . VAL A 1 130 ? -63.884 16.771 -22.201 1.00 60.47 ? 130 VAL A CG1 1 ATOM 589 C CG2 . VAL A 1 130 ? -64.277 14.475 -23.118 1.00 61.36 ? 130 VAL A CG2 1 ATOM 590 N N . SER A 1 131 ? -62.398 14.176 -19.586 1.00 50.93 ? 131 SER A N 1 ATOM 591 C CA . SER A 1 131 ? -62.241 14.168 -18.141 1.00 51.46 ? 131 SER A CA 1 ATOM 592 C C . SER A 1 131 ? -62.273 12.736 -17.625 1.00 54.20 ? 131 SER A C 1 ATOM 593 O O . SER A 1 131 ? -62.222 11.789 -18.408 1.00 61.75 ? 131 SER A O 1 ATOM 594 C CB . SER A 1 131 ? -63.353 14.986 -17.486 1.00 55.19 ? 131 SER A CB 1 ATOM 595 O OG . SER A 1 131 ? -63.301 14.870 -16.073 1.00 53.70 ? 131 SER A OG 1 ATOM 596 N N . PHE A 1 132 ? -62.360 12.584 -16.307 1.00 50.79 ? 132 PHE A N 1 ATOM 597 C CA . PHE A 1 132 ? -62.353 11.264 -15.682 1.00 54.33 ? 132 PHE A CA 1 ATOM 598 C C . PHE A 1 132 ? -63.712 10.567 -15.723 1.00 57.59 ? 132 PHE A C 1 ATOM 599 O O . PHE A 1 132 ? -63.825 9.397 -15.359 1.00 61.85 ? 132 PHE A O 1 ATOM 600 C CB . PHE A 1 132 ? -61.861 11.360 -14.232 1.00 52.01 ? 132 PHE A CB 1 ATOM 601 C CG . PHE A 1 132 ? -62.719 12.229 -13.349 1.00 51.44 ? 132 PHE A CG 1 ATOM 602 C CD1 . PHE A 1 132 ? -62.549 13.604 -13.331 1.00 52.94 ? 132 PHE A CD1 1 ATOM 603 C CD2 . PHE A 1 132 ? -63.681 11.668 -12.524 1.00 53.49 ? 132 PHE A CD2 1 ATOM 604 C CE1 . PHE A 1 132 ? -63.332 14.405 -12.519 1.00 50.75 ? 132 PHE A CE1 1 ATOM 605 C CE2 . PHE A 1 132 ? -64.467 12.464 -11.709 1.00 54.34 ? 132 PHE A CE2 1 ATOM 606 C CZ . PHE A 1 132 ? -64.291 13.834 -11.707 1.00 50.63 ? 132 PHE A CZ 1 ATOM 607 N N . PHE A 1 133 ? -64.736 11.281 -16.176 1.00 54.79 ? 133 PHE A N 1 ATOM 608 C CA . PHE A 1 133 ? -66.113 10.805 -16.050 1.00 67.02 ? 133 PHE A CA 1 ATOM 609 C C . PHE A 1 133 ? -66.459 9.523 -16.828 1.00 75.23 ? 133 PHE A C 1 ATOM 610 O O . PHE A 1 133 ? -66.996 8.577 -16.250 1.00 76.97 ? 133 PHE A O 1 ATOM 611 C CB . PHE A 1 133 ? -67.104 11.936 -16.358 1.00 66.69 ? 133 PHE A CB 1 ATOM 612 C CG . PHE A 1 133 ? -67.311 12.893 -15.209 1.00 67.12 ? 133 PHE A CG 1 ATOM 613 C CD1 . PHE A 1 133 ? -68.004 12.493 -14.075 1.00 65.36 ? 133 PHE A CD1 1 ATOM 614 C CD2 . PHE A 1 133 ? -66.825 14.191 -15.265 1.00 63.45 ? 133 PHE A CD2 1 ATOM 615 C CE1 . PHE A 1 133 ? -68.203 13.365 -13.016 1.00 57.83 ? 133 PHE A CE1 1 ATOM 616 C CE2 . PHE A 1 133 ? -67.023 15.070 -14.209 1.00 60.54 ? 133 PHE A CE2 1 ATOM 617 C CZ . PHE A 1 133 ? -67.712 14.655 -13.084 1.00 56.29 ? 133 PHE A CZ 1 ATOM 618 N N . ASP A 1 134 ? -66.168 9.489 -18.126 1.00 75.93 ? 134 ASP A N 1 ATOM 619 C CA . ASP A 1 134 ? -66.444 8.296 -18.936 1.00 87.55 ? 134 ASP A CA 1 ATOM 620 C C . ASP A 1 134 ? -65.239 7.358 -19.072 1.00 83.46 ? 134 ASP A C 1 ATOM 621 O O . ASP A 1 134 ? -65.275 6.386 -19.829 1.00 85.76 ? 134 ASP A O 1 ATOM 622 C CB . ASP A 1 134 ? -67.034 8.658 -20.305 1.00 104.70 ? 134 ASP A CB 1 ATOM 623 C CG . ASP A 1 134 ? -68.532 8.386 -20.384 1.00 109.49 ? 134 ASP A CG 1 ATOM 624 O OD1 . ASP A 1 134 ? -69.191 8.358 -19.321 1.00 93.29 ? 134 ASP A OD1 1 ATOM 625 O OD2 . ASP A 1 134 ? -69.053 8.201 -21.505 1.00 114.30 ? 134 ASP A OD2 1 ATOM 626 N N . SER A 1 135 ? -64.176 7.670 -18.338 1.00 74.48 ? 135 SER A N 1 ATOM 627 C CA . SER A 1 135 ? -62.960 6.861 -18.310 1.00 69.82 ? 135 SER A CA 1 ATOM 628 C C . SER A 1 135 ? -62.717 6.470 -16.867 1.00 59.66 ? 135 SER A C 1 ATOM 629 O O . SER A 1 135 ? -63.594 6.667 -16.028 1.00 61.56 ? 135 SER A O 1 ATOM 630 C CB . SER A 1 135 ? -61.767 7.639 -18.853 1.00 67.67 ? 135 SER A CB 1 ATOM 631 O OG . SER A 1 135 ? -61.873 7.807 -20.253 1.00 68.24 ? 135 SER A OG 1 ATOM 632 N N . SER A 1 136 ? -61.556 5.898 -16.562 1.00 58.46 ? 136 SER A N 1 ATOM 633 C CA . SER A 1 136 ? -61.351 5.429 -15.203 1.00 68.52 ? 136 SER A CA 1 ATOM 634 C C . SER A 1 136 ? -61.300 6.650 -14.295 1.00 62.98 ? 136 SER A C 1 ATOM 635 O O . SER A 1 136 ? -60.400 7.484 -14.397 1.00 60.12 ? 136 SER A O 1 ATOM 636 C CB . SER A 1 136 ? -60.035 4.657 -15.102 1.00 68.59 ? 136 SER A CB 1 ATOM 637 O OG . SER A 1 136 ? -59.926 3.692 -16.132 1.00 69.78 ? 136 SER A OG 1 ATOM 638 N N . PHE A 1 137 ? -62.286 6.730 -13.407 1.00 59.23 ? 137 PHE A N 1 ATOM 639 C CA . PHE A 1 137 ? -62.437 7.837 -12.468 1.00 53.27 ? 137 PHE A CA 1 ATOM 640 C C . PHE A 1 137 ? -61.632 7.644 -11.192 1.00 54.55 ? 137 PHE A C 1 ATOM 641 O O . PHE A 1 137 ? -61.128 8.605 -10.610 1.00 54.59 ? 137 PHE A O 1 ATOM 642 C CB . PHE A 1 137 ? -63.915 8.064 -12.142 1.00 48.50 ? 137 PHE A CB 1 ATOM 643 C CG . PHE A 1 137 ? -64.544 6.953 -11.348 1.00 46.56 ? 137 PHE A CG 1 ATOM 644 C CD1 . PHE A 1 137 ? -64.781 5.713 -11.922 1.00 52.40 ? 137 PHE A CD1 1 ATOM 645 C CD2 . PHE A 1 137 ? -64.916 7.157 -10.033 1.00 42.98 ? 137 PHE A CD2 1 ATOM 646 C CE1 . PHE A 1 137 ? -65.362 4.695 -11.192 1.00 48.24 ? 137 PHE A CE1 1 ATOM 647 C CE2 . PHE A 1 137 ? -65.499 6.143 -9.299 1.00 46.96 ? 137 PHE A CE2 1 ATOM 648 C CZ . PHE A 1 137 ? -65.722 4.911 -9.880 1.00 44.65 ? 137 PHE A CZ 1 ATOM 649 N N . ALA A 1 138 ? -61.538 6.389 -10.763 1.00 53.80 ? 138 ALA A N 1 ATOM 650 C CA . ALA A 1 138 ? -60.964 6.037 -9.466 1.00 52.75 ? 138 ALA A CA 1 ATOM 651 C C . ALA A 1 138 ? -59.590 6.650 -9.162 1.00 52.50 ? 138 ALA A C 1 ATOM 652 O O . ALA A 1 138 ? -59.419 7.268 -8.112 1.00 54.88 ? 138 ALA A O 1 ATOM 653 C CB . ALA A 1 138 ? -60.948 4.512 -9.277 1.00 53.52 ? 138 ALA A CB 1 ATOM 654 N N . PRO A 1 139 ? -58.608 6.488 -10.069 1.00 47.21 ? 139 PRO A N 1 ATOM 655 C CA . PRO A 1 139 ? -57.311 7.092 -9.742 1.00 46.51 ? 139 PRO A CA 1 ATOM 656 C C . PRO A 1 139 ? -57.310 8.619 -9.805 1.00 49.49 ? 139 PRO A C 1 ATOM 657 O O . PRO A 1 139 ? -56.417 9.235 -9.232 1.00 52.03 ? 139 PRO A O 1 ATOM 658 C CB . PRO A 1 139 ? -56.380 6.517 -10.812 1.00 43.82 ? 139 PRO A CB 1 ATOM 659 C CG . PRO A 1 139 ? -57.268 6.207 -11.954 1.00 47.95 ? 139 PRO A CG 1 ATOM 660 C CD . PRO A 1 139 ? -58.561 5.757 -11.350 1.00 48.49 ? 139 PRO A CD 1 ATOM 661 N N . TYR A 1 140 ? -58.283 9.217 -10.486 1.00 46.58 ? 140 TYR A N 1 ATOM 662 C CA . TYR A 1 140 ? -58.324 10.672 -10.639 1.00 43.86 ? 140 TYR A CA 1 ATOM 663 C C . TYR A 1 140 ? -59.042 11.356 -9.481 1.00 47.80 ? 140 TYR A C 1 ATOM 664 O O . TYR A 1 140 ? -59.195 12.577 -9.459 1.00 46.28 ? 140 TYR A O 1 ATOM 665 C CB . TYR A 1 140 ? -58.965 11.052 -11.973 1.00 43.43 ? 140 TYR A CB 1 ATOM 666 C CG . TYR A 1 140 ? -58.109 10.686 -13.159 1.00 41.14 ? 140 TYR A CG 1 ATOM 667 C CD1 . TYR A 1 140 ? -57.330 11.640 -13.794 1.00 36.78 ? 140 TYR A CD1 1 ATOM 668 C CD2 . TYR A 1 140 ? -58.066 9.383 -13.632 1.00 41.87 ? 140 TYR A CD2 1 ATOM 669 C CE1 . TYR A 1 140 ? -56.544 11.307 -14.873 1.00 38.72 ? 140 TYR A CE1 1 ATOM 670 C CE2 . TYR A 1 140 ? -57.284 9.043 -14.708 1.00 36.91 ? 140 TYR A CE2 1 ATOM 671 C CZ . TYR A 1 140 ? -56.522 10.007 -15.324 1.00 40.09 ? 140 TYR A CZ 1 ATOM 672 O OH . TYR A 1 140 ? -55.739 9.669 -16.402 1.00 44.25 ? 140 TYR A OH 1 ATOM 673 N N . LEU A 1 141 ? -59.486 10.549 -8.527 1.00 53.96 ? 141 LEU A N 1 ATOM 674 C CA . LEU A 1 141 ? -60.100 11.037 -7.301 1.00 53.25 ? 141 LEU A CA 1 ATOM 675 C C . LEU A 1 141 ? -59.168 10.737 -6.132 1.00 47.99 ? 141 LEU A C 1 ATOM 676 O O . LEU A 1 141 ? -58.748 11.633 -5.405 1.00 46.94 ? 141 LEU A O 1 ATOM 677 C CB . LEU A 1 141 ? -61.480 10.407 -7.100 1.00 55.94 ? 141 LEU A CB 1 ATOM 678 C CG . LEU A 1 141 ? -62.472 10.701 -8.230 1.00 55.96 ? 141 LEU A CG 1 ATOM 679 C CD1 . LEU A 1 141 ? -63.848 10.122 -7.931 1.00 57.52 ? 141 LEU A CD1 1 ATOM 680 C CD2 . LEU A 1 141 ? -62.561 12.198 -8.493 1.00 54.93 ? 141 LEU A CD2 1 ATOM 681 N N . THR A 1 142 ? -58.874 9.454 -5.951 1.00 44.63 ? 142 THR A N 1 ATOM 682 C CA . THR A 1 142 ? -57.991 8.987 -4.889 1.00 55.53 ? 142 THR A CA 1 ATOM 683 C C . THR A 1 142 ? -56.567 9.565 -4.945 1.00 62.70 ? 142 THR A C 1 ATOM 684 O O . THR A 1 142 ? -55.825 9.464 -3.969 1.00 69.99 ? 142 THR A O 1 ATOM 685 C CB . THR A 1 142 ? -57.905 7.450 -4.895 1.00 61.33 ? 142 THR A CB 1 ATOM 686 O OG1 . THR A 1 142 ? -57.190 7.015 -6.057 1.00 63.52 ? 142 THR A OG1 1 ATOM 687 C CG2 . THR A 1 142 ? -59.299 6.835 -4.904 1.00 51.34 ? 142 THR A CG2 1 ATOM 688 N N . THR A 1 143 ? -56.184 10.157 -6.075 1.00 57.63 ? 143 THR A N 1 ATOM 689 C CA . THR A 1 143 ? -54.823 10.681 -6.240 1.00 58.18 ? 143 THR A CA 1 ATOM 690 C C . THR A 1 143 ? -54.482 11.813 -5.268 1.00 58.11 ? 143 THR A C 1 ATOM 691 O O . THR A 1 143 ? -55.341 12.617 -4.905 1.00 57.61 ? 143 THR A O 1 ATOM 692 C CB . THR A 1 143 ? -54.544 11.147 -7.690 1.00 57.53 ? 143 THR A CB 1 ATOM 693 O OG1 . THR A 1 143 ? -53.176 11.559 -7.815 1.00 57.69 ? 143 THR A OG1 1 ATOM 694 C CG2 . THR A 1 143 ? -55.459 12.299 -8.077 1.00 52.05 ? 143 THR A CG2 1 ATOM 695 N N . GLN A 1 144 ? -53.221 11.861 -4.849 1.00 58.66 ? 144 GLN A N 1 ATOM 696 C CA . GLN A 1 144 ? -52.753 12.884 -3.923 1.00 61.07 ? 144 GLN A CA 1 ATOM 697 C C . GLN A 1 144 ? -52.155 14.059 -4.697 1.00 60.37 ? 144 GLN A C 1 ATOM 698 O O . GLN A 1 144 ? -51.669 15.024 -4.106 1.00 62.56 ? 144 GLN A O 1 ATOM 699 C CB . GLN A 1 144 ? -51.723 12.292 -2.955 1.00 58.83 ? 144 GLN A CB 1 ATOM 700 C CG . GLN A 1 144 ? -51.619 13.007 -1.612 1.00 58.00 ? 144 GLN A CG 1 ATOM 701 C CD . GLN A 1 144 ? -52.843 12.806 -0.737 1.00 65.23 ? 144 GLN A CD 1 ATOM 702 O OE1 . GLN A 1 144 ? -53.631 11.885 -0.952 1.00 65.54 ? 144 GLN A OE1 1 ATOM 703 N NE2 . GLN A 1 144 ? -53.007 13.670 0.259 1.00 71.20 ? 144 GLN A NE2 1 ATOM 704 N N . HIS A 1 145 ? -52.201 13.964 -6.024 1.00 55.21 ? 145 HIS A N 1 ATOM 705 C CA . HIS A 1 145 ? -51.709 15.018 -6.908 1.00 53.55 ? 145 HIS A CA 1 ATOM 706 C C . HIS A 1 145 ? -52.411 16.342 -6.630 1.00 53.97 ? 145 HIS A C 1 ATOM 707 O O . HIS A 1 145 ? -53.595 16.364 -6.294 1.00 56.51 ? 145 HIS A O 1 ATOM 708 C CB . HIS A 1 145 ? -51.904 14.610 -8.371 1.00 52.72 ? 145 HIS A CB 1 ATOM 709 C CG . HIS A 1 145 ? -51.713 15.728 -9.350 1.00 50.15 ? 145 HIS A CG 1 ATOM 710 N ND1 . HIS A 1 145 ? -50.577 16.509 -9.384 1.00 56.12 ? 145 HIS A ND1 1 ATOM 711 C CD2 . HIS A 1 145 ? -52.511 16.185 -10.345 1.00 46.44 ? 145 HIS A CD2 1 ATOM 712 C CE1 . HIS A 1 145 ? -50.688 17.403 -10.350 1.00 54.99 ? 145 HIS A CE1 1 ATOM 713 N NE2 . HIS A 1 145 ? -51.852 17.228 -10.948 1.00 47.34 ? 145 HIS A NE2 1 ATOM 714 N N . LEU A 1 146 ? -51.657 17.434 -6.754 1.00 56.07 ? 146 LEU A N 1 ATOM 715 C CA . LEU A 1 146 ? -52.134 18.797 -6.487 1.00 58.80 ? 146 LEU A CA 1 ATOM 716 C C . LEU A 1 146 ? -52.408 19.090 -5.007 1.00 65.40 ? 146 LEU A C 1 ATOM 717 O O . LEU A 1 146 ? -52.563 20.247 -4.620 1.00 65.42 ? 146 LEU A O 1 ATOM 718 C CB . LEU A 1 146 ? -53.346 19.156 -7.359 1.00 54.34 ? 146 LEU A CB 1 ATOM 719 C CG . LEU A 1 146 ? -53.060 19.446 -8.833 1.00 52.84 ? 146 LEU A CG 1 ATOM 720 C CD1 . LEU A 1 146 ? -54.352 19.537 -9.618 1.00 56.84 ? 146 LEU A CD1 1 ATOM 721 C CD2 . LEU A 1 146 ? -52.265 20.729 -8.979 1.00 56.26 ? 146 LEU A CD2 1 ATOM 722 N N . VAL A 1 147 ? -52.439 18.047 -4.183 1.00 65.96 ? 147 VAL A N 1 ATOM 723 C CA . VAL A 1 147 ? -52.631 18.205 -2.744 1.00 67.47 ? 147 VAL A CA 1 ATOM 724 C C . VAL A 1 147 ? -51.292 18.151 -2.014 1.00 69.02 ? 147 VAL A C 1 ATOM 725 O O . VAL A 1 147 ? -50.879 19.128 -1.387 1.00 75.18 ? 147 VAL A O 1 ATOM 726 C CB . VAL A 1 147 ? -53.581 17.136 -2.173 1.00 66.05 ? 147 VAL A CB 1 ATOM 727 C CG1 . VAL A 1 147 ? -53.543 17.141 -0.650 1.00 76.35 ? 147 VAL A CG1 1 ATOM 728 C CG2 . VAL A 1 147 ? -54.997 17.367 -2.675 1.00 59.97 ? 147 VAL A CG2 1 ATOM 729 N N . ALA A 1 148 ? -50.629 17.000 -2.075 1.00 65.80 ? 148 ALA A N 1 ATOM 730 C CA . ALA A 1 148 ? -49.291 16.862 -1.514 1.00 75.04 ? 148 ALA A CA 1 ATOM 731 C C . ALA A 1 148 ? -48.220 17.394 -2.463 1.00 75.98 ? 148 ALA A C 1 ATOM 732 O O . ALA A 1 148 ? -47.215 17.949 -2.025 1.00 82.69 ? 148 ALA A O 1 ATOM 733 C CB . ALA A 1 148 ? -49.009 15.411 -1.155 1.00 74.25 ? 148 ALA A CB 1 ATOM 734 N N . PHE A 1 149 ? -48.443 17.220 -3.763 1.00 66.07 ? 149 PHE A N 1 ATOM 735 C CA . PHE A 1 149 ? -47.452 17.582 -4.772 1.00 61.19 ? 149 PHE A CA 1 ATOM 736 C C . PHE A 1 149 ? -48.081 17.795 -6.141 1.00 61.46 ? 149 PHE A C 1 ATOM 737 O O . PHE A 1 149 ? -49.198 17.347 -6.391 1.00 66.98 ? 149 PHE A O 1 ATOM 738 C CB . PHE A 1 149 ? -46.409 16.473 -4.885 1.00 61.12 ? 149 PHE A CB 1 ATOM 739 C CG . PHE A 1 149 ? -47.003 15.102 -5.051 1.00 56.33 ? 149 PHE A CG 1 ATOM 740 C CD1 . PHE A 1 149 ? -47.418 14.650 -6.294 1.00 54.31 ? 149 PHE A CD1 1 ATOM 741 C CD2 . PHE A 1 149 ? -47.146 14.265 -3.960 1.00 59.25 ? 149 PHE A CD2 1 ATOM 742 C CE1 . PHE A 1 149 ? -47.966 13.391 -6.441 1.00 52.53 ? 149 PHE A CE1 1 ATOM 743 C CE2 . PHE A 1 149 ? -47.691 13.004 -4.101 1.00 58.60 ? 149 PHE A CE2 1 ATOM 744 C CZ . PHE A 1 149 ? -48.101 12.566 -5.343 1.00 52.10 ? 149 PHE A CZ 1 ATOM 745 N N . THR A 1 150 ? -47.359 18.474 -7.029 1.00 62.11 ? 150 THR A N 1 ATOM 746 C CA . THR A 1 150 ? -47.687 18.451 -8.451 1.00 60.26 ? 150 THR A CA 1 ATOM 747 C C . THR A 1 150 ? -46.611 17.652 -9.167 1.00 62.74 ? 150 THR A C 1 ATOM 748 O O . THR A 1 150 ? -45.423 17.836 -8.905 1.00 70.09 ? 150 THR A O 1 ATOM 749 C CB . THR A 1 150 ? -47.758 19.863 -9.085 1.00 56.29 ? 150 THR A CB 1 ATOM 750 O OG1 . THR A 1 150 ? -46.445 20.434 -9.154 1.00 59.81 ? 150 THR A OG1 1 ATOM 751 C CG2 . THR A 1 150 ? -48.673 20.773 -8.294 1.00 63.81 ? 150 THR A CG2 1 ATOM 752 N N . THR A 1 151 ? -47.022 16.760 -10.062 1.00 60.31 ? 151 THR A N 1 ATOM 753 C CA . THR A 1 151 ? -46.070 15.994 -10.859 1.00 65.17 ? 151 THR A CA 1 ATOM 754 C C . THR A 1 151 ? -45.338 16.946 -11.803 1.00 70.68 ? 151 THR A C 1 ATOM 755 O O . THR A 1 151 ? -44.213 16.684 -12.231 1.00 70.29 ? 151 THR A O 1 ATOM 756 C CB . THR A 1 151 ? -46.771 14.887 -11.666 1.00 58.36 ? 151 THR A CB 1 ATOM 757 O OG1 . THR A 1 151 ? -47.586 14.097 -10.792 1.00 49.78 ? 151 THR A OG1 1 ATOM 758 C CG2 . THR A 1 151 ? -45.755 13.986 -12.348 1.00 56.70 ? 151 THR A CG2 1 ATOM 759 N N . PHE A 1 152 ? -45.993 18.062 -12.108 1.00 71.48 ? 152 PHE A N 1 ATOM 760 C CA . PHE A 1 152 ? -45.425 19.100 -12.956 1.00 71.87 ? 152 PHE A CA 1 ATOM 761 C C . PHE A 1 152 ? -44.559 20.040 -12.127 1.00 69.11 ? 152 PHE A C 1 ATOM 762 O O . PHE A 1 152 ? -44.761 20.172 -10.919 1.00 69.11 ? 152 PHE A O 1 ATOM 763 C CB . PHE A 1 152 ? -46.545 19.919 -13.600 1.00 69.22 ? 152 PHE A CB 1 ATOM 764 C CG . PHE A 1 152 ? -47.616 19.093 -14.253 1.00 62.59 ? 152 PHE A CG 1 ATOM 765 C CD1 . PHE A 1 152 ? -47.295 17.967 -14.992 1.00 61.37 ? 152 PHE A CD1 1 ATOM 766 C CD2 . PHE A 1 152 ? -48.949 19.452 -14.129 1.00 60.89 ? 152 PHE A CD2 1 ATOM 767 C CE1 . PHE A 1 152 ? -48.286 17.215 -15.593 1.00 61.61 ? 152 PHE A CE1 1 ATOM 768 C CE2 . PHE A 1 152 ? -49.942 18.705 -14.726 1.00 58.19 ? 152 PHE A CE2 1 ATOM 769 C CZ . PHE A 1 152 ? -49.610 17.588 -15.460 1.00 59.05 ? 152 PHE A CZ 1 ATOM 770 N N . PRO A 1 153 ? -43.587 20.702 -12.774 1.00 67.51 ? 153 PRO A N 1 ATOM 771 C CA . PRO A 1 153 ? -42.885 21.798 -12.100 1.00 69.72 ? 153 PRO A CA 1 ATOM 772 C C . PRO A 1 153 ? -43.864 22.939 -11.853 1.00 66.62 ? 153 PRO A C 1 ATOM 773 O O . PRO A 1 153 ? -44.766 23.140 -12.665 1.00 66.72 ? 153 PRO A O 1 ATOM 774 C CB . PRO A 1 153 ? -41.819 22.213 -13.119 1.00 78.21 ? 153 PRO A CB 1 ATOM 775 C CG . PRO A 1 153 ? -42.332 21.727 -14.436 1.00 76.72 ? 153 PRO A CG 1 ATOM 776 C CD . PRO A 1 153 ? -43.060 20.456 -14.127 1.00 71.76 ? 153 PRO A CD 1 ATOM 777 N N . PRO A 1 154 ? -43.689 23.681 -10.749 1.00 67.37 ? 154 PRO A N 1 ATOM 778 C CA . PRO A 1 154 ? -44.670 24.684 -10.317 1.00 70.37 ? 154 PRO A CA 1 ATOM 779 C C . PRO A 1 154 ? -44.874 25.823 -11.317 1.00 68.35 ? 154 PRO A C 1 ATOM 780 O O . PRO A 1 154 ? -45.975 26.369 -11.403 1.00 71.50 ? 154 PRO A O 1 ATOM 781 C CB . PRO A 1 154 ? -44.070 25.219 -9.010 1.00 75.50 ? 154 PRO A CB 1 ATOM 782 C CG . PRO A 1 154 ? -42.610 24.951 -9.126 1.00 81.62 ? 154 PRO A CG 1 ATOM 783 C CD . PRO A 1 154 ? -42.500 23.661 -9.880 1.00 78.07 ? 154 PRO A CD 1 ATOM 784 N N . ASN A 1 155 ? -43.830 26.168 -12.062 1.00 65.00 ? 155 ASN A N 1 ATOM 785 C CA . ASN A 1 155 ? -43.900 27.256 -13.029 1.00 67.20 ? 155 ASN A CA 1 ATOM 786 C C . ASN A 1 155 ? -44.267 26.761 -14.427 1.00 68.14 ? 155 ASN A C 1 ATOM 787 O O . ASN A 1 155 ? -43.532 25.975 -15.021 1.00 73.17 ? 155 ASN A O 1 ATOM 788 C CB . ASN A 1 155 ? -42.567 28.006 -13.063 1.00 72.56 ? 155 ASN A CB 1 ATOM 789 C CG . ASN A 1 155 ? -42.555 29.146 -14.063 1.00 74.79 ? 155 ASN A CG 1 ATOM 790 O OD1 . ASN A 1 155 ? -43.601 29.663 -14.454 1.00 69.37 ? 155 ASN A OD1 1 ATOM 791 N ND2 . ASN A 1 155 ? -41.361 29.550 -14.477 1.00 80.01 ? 155 ASN A ND2 1 ATOM 792 N N . PRO A 1 156 ? -45.413 27.225 -14.952 1.00 69.81 ? 156 PRO A N 1 ATOM 793 C CA . PRO A 1 156 ? -45.926 26.875 -16.284 1.00 71.46 ? 156 PRO A CA 1 ATOM 794 C C . PRO A 1 156 ? -44.992 27.294 -17.420 1.00 74.02 ? 156 PRO A C 1 ATOM 795 O O . PRO A 1 156 ? -45.139 26.812 -18.546 1.00 73.98 ? 156 PRO A O 1 ATOM 796 C CB . PRO A 1 156 ? -47.248 27.652 -16.368 1.00 73.22 ? 156 PRO A CB 1 ATOM 797 C CG . PRO A 1 156 ? -47.147 28.717 -15.321 1.00 79.66 ? 156 PRO A CG 1 ATOM 798 C CD . PRO A 1 156 ? -46.340 28.106 -14.223 1.00 80.43 ? 156 PRO A CD 1 ATOM 799 N N . LEU A 1 157 ? -44.052 28.186 -17.122 1.00 69.62 ? 157 LEU A N 1 ATOM 800 C CA . LEU A 1 157 ? -43.085 28.664 -18.106 1.00 67.01 ? 157 LEU A CA 1 ATOM 801 C C . LEU A 1 157 ? -42.011 27.618 -18.418 1.00 63.50 ? 157 LEU A C 1 ATOM 802 O O . LEU A 1 157 ? -41.487 27.567 -19.532 1.00 59.36 ? 157 LEU A O 1 ATOM 803 C CB . LEU A 1 157 ? -42.425 29.952 -17.609 1.00 70.98 ? 157 LEU A CB 1 ATOM 804 C CG . LEU A 1 157 ? -43.337 31.158 -17.364 1.00 70.52 ? 157 LEU A CG 1 ATOM 805 C CD1 . LEU A 1 157 ? -42.586 32.280 -16.654 1.00 70.30 ? 157 LEU A CD1 1 ATOM 806 C CD2 . LEU A 1 157 ? -43.930 31.653 -18.673 1.00 61.11 ? 157 LEU A CD2 1 ATOM 807 N N . VAL A 1 158 ? -41.704 26.778 -17.434 1.00 64.62 ? 158 VAL A N 1 ATOM 808 C CA . VAL A 1 158 ? -40.645 25.777 -17.558 1.00 65.56 ? 158 VAL A CA 1 ATOM 809 C C . VAL A 1 158 ? -41.134 24.518 -18.284 1.00 66.68 ? 158 VAL A C 1 ATOM 810 O O . VAL A 1 158 ? -40.369 23.581 -18.516 1.00 71.52 ? 158 VAL A O 1 ATOM 811 C CB . VAL A 1 158 ? -40.085 25.388 -16.169 1.00 67.49 ? 158 VAL A CB 1 ATOM 812 C CG1 . VAL A 1 158 ? -38.684 24.810 -16.289 1.00 87.70 ? 158 VAL A CG1 1 ATOM 813 C CG2 . VAL A 1 158 ? -40.060 26.596 -15.254 1.00 67.21 ? 158 VAL A CG2 1 ATOM 814 N N . TRP A 1 159 ? -42.406 24.512 -18.667 1.00 67.10 ? 159 TRP A N 1 ATOM 815 C CA . TRP A 1 159 ? -43.018 23.324 -19.252 1.00 65.13 ? 159 TRP A CA 1 ATOM 816 C C . TRP A 1 159 ? -42.547 23.077 -20.680 1.00 64.75 ? 159 TRP A C 1 ATOM 817 O O . TRP A 1 159 ? -41.915 22.057 -20.958 1.00 65.52 ? 159 TRP A O 1 ATOM 818 C CB . TRP A 1 159 ? -44.547 23.404 -19.188 1.00 61.82 ? 159 TRP A CB 1 ATOM 819 C CG . TRP A 1 159 ? -45.094 23.350 -17.786 1.00 66.45 ? 159 TRP A CG 1 ATOM 820 C CD1 . TRP A 1 159 ? -44.437 23.675 -16.637 1.00 67.05 ? 159 TRP A CD1 1 ATOM 821 C CD2 . TRP A 1 159 ? -46.406 22.930 -17.389 1.00 67.93 ? 159 TRP A CD2 1 ATOM 822 N NE1 . TRP A 1 159 ? -45.258 23.495 -15.551 1.00 59.99 ? 159 TRP A NE1 1 ATOM 823 C CE2 . TRP A 1 159 ? -46.473 23.036 -15.986 1.00 63.70 ? 159 TRP A CE2 1 ATOM 824 C CE3 . TRP A 1 159 ? -47.530 22.478 -18.083 1.00 71.15 ? 159 TRP A CE3 1 ATOM 825 C CZ2 . TRP A 1 159 ? -47.620 22.709 -15.266 1.00 64.01 ? 159 TRP A CZ2 1 ATOM 826 C CZ3 . TRP A 1 159 ? -48.668 22.151 -17.366 1.00 67.01 ? 159 TRP A CZ3 1 ATOM 827 C CH2 . TRP A 1 159 ? -48.703 22.267 -15.973 1.00 61.86 ? 159 TRP A CH2 1 ATOM 828 N N . HIS A 1 160 ? -42.859 24.001 -21.585 1.00 65.83 ? 160 HIS A N 1 ATOM 829 C CA . HIS A 1 160 ? -42.461 23.852 -22.980 1.00 60.01 ? 160 HIS A CA 1 ATOM 830 C C . HIS A 1 160 ? -40.948 23.745 -23.101 1.00 59.32 ? 160 HIS A C 1 ATOM 831 O O . HIS A 1 160 ? -40.214 24.518 -22.489 1.00 63.38 ? 160 HIS A O 1 ATOM 832 C CB . HIS A 1 160 ? -42.957 25.023 -23.823 1.00 59.45 ? 160 HIS A CB 1 ATOM 833 C CG . HIS A 1 160 ? -42.612 24.903 -25.274 1.00 66.70 ? 160 HIS A CG 1 ATOM 834 N ND1 . HIS A 1 160 ? -41.386 25.274 -25.781 1.00 67.71 ? 160 HIS A ND1 1 ATOM 835 C CD2 . HIS A 1 160 ? -43.330 24.443 -26.326 1.00 69.44 ? 160 HIS A CD2 1 ATOM 836 C CE1 . HIS A 1 160 ? -41.364 25.053 -27.083 1.00 66.31 ? 160 HIS A CE1 1 ATOM 837 N NE2 . HIS A 1 160 ? -42.532 24.549 -27.439 1.00 68.13 ? 160 HIS A NE2 1 ATOM 838 N N . LEU A 1 161 ? -40.493 22.781 -23.894 1.00 60.55 ? 161 LEU A N 1 ATOM 839 C CA . LEU A 1 161 ? -39.068 22.536 -24.071 1.00 62.96 ? 161 LEU A CA 1 ATOM 840 C C . LEU A 1 161 ? -38.650 22.686 -25.528 1.00 66.52 ? 161 LEU A C 1 ATOM 841 O O . LEU A 1 161 ? -39.483 22.626 -26.433 1.00 67.95 ? 161 LEU A O 1 ATOM 842 C CB . LEU A 1 161 ? -38.695 21.140 -23.566 1.00 60.17 ? 161 LEU A CB 1 ATOM 843 C CG . LEU A 1 161 ? -38.640 20.933 -22.054 1.00 66.43 ? 161 LEU A CG 1 ATOM 844 C CD1 . LEU A 1 161 ? -38.180 19.520 -21.718 1.00 70.95 ? 161 LEU A CD1 1 ATOM 845 C CD2 . LEU A 1 161 ? -37.730 21.963 -21.400 1.00 68.67 ? 161 LEU A CD2 1 ATOM 846 N N . GLU A 1 162 ? -37.356 22.888 -25.748 1.00 63.61 ? 162 GLU A N 1 ATOM 847 C CA . GLU A 1 162 ? -36.827 22.991 -27.099 1.00 63.67 ? 162 GLU A CA 1 ATOM 848 C C . GLU A 1 162 ? -36.565 21.596 -27.654 1.00 61.30 ? 162 GLU A C 1 ATOM 849 O O . GLU A 1 162 ? -36.057 20.727 -26.948 1.00 57.22 ? 162 GLU A O 1 ATOM 850 C CB . GLU A 1 162 ? -35.537 23.813 -27.107 1.00 67.33 ? 162 GLU A CB 1 ATOM 851 C CG . GLU A 1 162 ? -35.427 24.778 -28.274 1.00 65.77 ? 162 GLU A CG 1 ATOM 852 C CD . GLU A 1 162 ? -36.523 25.822 -28.260 1.00 72.13 ? 162 GLU A CD 1 ATOM 853 O OE1 . GLU A 1 162 ? -36.454 26.747 -27.424 1.00 74.16 ? 162 GLU A OE1 1 ATOM 854 O OE2 . GLU A 1 162 ? -37.458 25.713 -29.080 1.00 75.38 ? 162 GLU A OE2 1 ATOM 855 N N . ARG A 1 163 ? -36.924 21.378 -28.915 1.00 56.43 ? 163 ARG A N 1 ATOM 856 C CA . ARG A 1 163 ? -36.662 20.098 -29.563 1.00 56.56 ? 163 ARG A CA 1 ATOM 857 C C . ARG A 1 163 ? -35.184 19.959 -29.921 1.00 69.22 ? 163 ARG A C 1 ATOM 858 O O . ARG A 1 163 ? -34.597 20.856 -30.525 1.00 75.06 ? 163 ARG A O 1 ATOM 859 C CB . ARG A 1 163 ? -37.533 19.929 -30.809 1.00 52.08 ? 163 ARG A CB 1 ATOM 860 C CG . ARG A 1 163 ? -38.043 21.229 -31.414 1.00 47.37 ? 163 ARG A CG 1 ATOM 861 C CD . ARG A 1 163 ? -38.869 20.968 -32.671 1.00 49.85 ? 163 ARG A CD 1 ATOM 862 N NE . ARG A 1 163 ? -39.751 19.811 -32.528 1.00 47.13 ? 163 ARG A NE 1 ATOM 863 C CZ . ARG A 1 163 ? -39.544 18.637 -33.116 1.00 48.68 ? 163 ARG A CZ 1 ATOM 864 N NH1 . ARG A 1 163 ? -38.483 18.462 -33.891 1.00 54.54 ? 163 ARG A NH1 1 ATOM 865 N NH2 . ARG A 1 163 ? -40.393 17.637 -32.927 1.00 45.07 ? 163 ARG A NH2 1 ATOM 866 N N . ALA A 1 164 ? -34.590 18.829 -29.548 1.00 70.34 ? 164 ALA A N 1 ATOM 867 C CA . ALA A 1 164 ? -33.167 18.594 -29.785 1.00 71.92 ? 164 ALA A CA 1 ATOM 868 C C . ALA A 1 164 ? -32.872 18.477 -31.274 1.00 66.32 ? 164 ALA A C 1 ATOM 869 O O . ALA A 1 164 ? -33.771 18.221 -32.071 1.00 64.14 ? 164 ALA A O 1 ATOM 870 C CB . ALA A 1 164 ? -32.704 17.348 -29.053 1.00 79.69 ? 164 ALA A CB 1 ATOM 871 N N . GLU A 1 165 ? -31.610 18.674 -31.644 1.00 76.80 ? 165 GLU A N 1 ATOM 872 C CA . GLU A 1 165 ? -31.205 18.626 -33.047 1.00 83.39 ? 165 GLU A CA 1 ATOM 873 C C . GLU A 1 165 ? -31.452 17.261 -33.679 1.00 72.58 ? 165 GLU A C 1 ATOM 874 O O . GLU A 1 165 ? -31.674 17.157 -34.885 1.00 66.13 ? 165 GLU A O 1 ATOM 875 C CB . GLU A 1 165 ? -29.728 18.998 -33.198 1.00 95.62 ? 165 GLU A CB 1 ATOM 876 C CG . GLU A 1 165 ? -29.423 20.473 -32.999 1.00 103.88 ? 165 GLU A CG 1 ATOM 877 C CD . GLU A 1 165 ? -28.022 20.836 -33.453 1.00 116.30 ? 165 GLU A CD 1 ATOM 878 O OE1 . GLU A 1 165 ? -27.134 19.959 -33.403 1.00 120.85 ? 165 GLU A OE1 1 ATOM 879 O OE2 . GLU A 1 165 ? -27.812 21.994 -33.869 1.00 122.15 ? 165 GLU A OE2 1 ATOM 880 N N . THR A 1 166 ? -31.423 16.220 -32.855 1.00 67.71 ? 166 THR A N 1 ATOM 881 C CA . THR A 1 166 ? -31.560 14.855 -33.344 1.00 64.38 ? 166 THR A CA 1 ATOM 882 C C . THR A 1 166 ? -33.024 14.489 -33.569 1.00 61.26 ? 166 THR A C 1 ATOM 883 O O . THR A 1 166 ? -33.333 13.392 -34.034 1.00 57.20 ? 166 THR A O 1 ATOM 884 C CB . THR A 1 166 ? -30.928 13.844 -32.370 1.00 55.65 ? 166 THR A CB 1 ATOM 885 O OG1 . THR A 1 166 ? -31.713 13.771 -31.174 1.00 57.47 ? 166 THR A OG1 1 ATOM 886 C CG2 . THR A 1 166 ? -29.510 14.264 -32.012 1.00 52.19 ? 166 THR A CG2 1 ATOM 887 N N . ALA A 1 167 ? -33.922 15.413 -33.239 1.00 65.38 ? 167 ALA A N 1 ATOM 888 C CA . ALA A 1 167 ? -35.351 15.203 -33.445 1.00 64.76 ? 167 ALA A CA 1 ATOM 889 C C . ALA A 1 167 ? -35.706 15.314 -34.923 1.00 56.50 ? 167 ALA A C 1 ATOM 890 O O . ALA A 1 167 ? -34.975 15.927 -35.698 1.00 67.03 ? 167 ALA A O 1 ATOM 891 C CB . ALA A 1 167 ? -36.157 16.195 -32.632 1.00 73.85 ? 167 ALA A CB 1 ATOM 892 N N . ALA A 1 168 ? -36.838 14.733 -35.305 1.00 49.12 ? 168 ALA A N 1 ATOM 893 C CA . ALA A 1 168 ? -37.243 14.682 -36.708 1.00 61.44 ? 168 ALA A CA 1 ATOM 894 C C . ALA A 1 168 ? -37.588 16.058 -37.278 1.00 66.51 ? 168 ALA A C 1 ATOM 895 O O . ALA A 1 168 ? -37.896 16.990 -36.535 1.00 63.21 ? 168 ALA A O 1 ATOM 896 C CB . ALA A 1 168 ? -38.412 13.728 -36.881 1.00 63.77 ? 168 ALA A CB 1 ATOM 897 N N . THR A 1 169 ? -37.525 16.176 -38.603 1.00 70.73 ? 169 THR A N 1 ATOM 898 C CA . THR A 1 169 ? -37.888 17.411 -39.298 1.00 72.31 ? 169 THR A CA 1 ATOM 899 C C . THR A 1 169 ? -38.800 17.105 -40.484 1.00 77.16 ? 169 THR A C 1 ATOM 900 O O . THR A 1 169 ? -39.143 15.949 -40.722 1.00 78.61 ? 169 THR A O 1 ATOM 901 C CB . THR A 1 169 ? -36.646 18.165 -39.809 1.00 73.41 ? 169 THR A CB 1 ATOM 902 O OG1 . THR A 1 169 ? -35.880 17.304 -40.660 1.00 83.23 ? 169 THR A OG1 1 ATOM 903 C CG2 . THR A 1 169 ? -35.779 18.625 -38.648 1.00 75.10 ? 169 THR A CG2 1 ATOM 904 N N . ALA A 1 170 ? -39.193 18.137 -41.225 1.00 81.68 ? 170 ALA A N 1 ATOM 905 C CA . ALA A 1 170 ? -40.074 17.953 -42.376 1.00 87.06 ? 170 ALA A CA 1 ATOM 906 C C . ALA A 1 170 ? -39.385 17.179 -43.499 1.00 91.15 ? 170 ALA A C 1 ATOM 907 O O . ALA A 1 170 ? -40.038 16.480 -44.275 1.00 93.84 ? 170 ALA A O 1 ATOM 908 C CB . ALA A 1 170 ? -40.584 19.297 -42.884 1.00 87.55 ? 170 ALA A CB 1 ATOM 909 N N . GLU A 1 171 ? -38.064 17.305 -43.578 1.00 88.70 ? 171 GLU A N 1 ATOM 910 C CA . GLU A 1 171 ? -37.282 16.589 -44.579 1.00 95.57 ? 171 GLU A CA 1 ATOM 911 C C . GLU A 1 171 ? -37.171 15.111 -44.213 1.00 90.30 ? 171 GLU A C 1 ATOM 912 O O . GLU A 1 171 ? -37.270 14.238 -45.075 1.00 92.82 ? 171 GLU A O 1 ATOM 913 C CB . GLU A 1 171 ? -35.887 17.207 -44.710 1.00 106.47 ? 171 GLU A CB 1 ATOM 914 C CG . GLU A 1 171 ? -35.017 16.601 -45.809 1.00 118.77 ? 171 GLU A CG 1 ATOM 915 C CD . GLU A 1 171 ? -35.367 17.113 -47.198 1.00 124.51 ? 171 GLU A CD 1 ATOM 916 O OE1 . GLU A 1 171 ? -34.563 17.880 -47.769 1.00 102.45 ? 171 GLU A OE1 1 ATOM 917 O OE2 . GLU A 1 171 ? -36.439 16.742 -47.723 1.00 130.66 ? 171 GLU A OE2 1 ATOM 918 N N . ARG A 1 172 ? -36.962 14.842 -42.928 1.00 84.76 ? 172 ARG A N 1 ATOM 919 C CA . ARG A 1 172 ? -36.883 13.474 -42.427 1.00 84.41 ? 172 ARG A CA 1 ATOM 920 C C . ARG A 1 172 ? -37.977 13.249 -41.389 1.00 78.30 ? 172 ARG A C 1 ATOM 921 O O . ARG A 1 172 ? -37.725 13.334 -40.186 1.00 73.95 ? 172 ARG A O 1 ATOM 922 C CB . ARG A 1 172 ? -35.506 13.195 -41.816 1.00 93.28 ? 172 ARG A CB 1 ATOM 923 C CG . ARG A 1 172 ? -34.330 13.619 -42.692 1.00 101.95 ? 172 ARG A CG 1 ATOM 924 C CD . ARG A 1 172 ? -32.999 13.110 -42.143 1.00 101.15 ? 172 ARG A CD 1 ATOM 925 N NE . ARG A 1 172 ? -32.022 14.184 -41.979 1.00 95.23 ? 172 ARG A NE 1 ATOM 926 C CZ . ARG A 1 172 ? -31.723 14.751 -40.815 1.00 89.23 ? 172 ARG A CZ 1 ATOM 927 N NH1 . ARG A 1 172 ? -32.318 14.342 -39.703 1.00 87.21 ? 172 ARG A NH1 1 ATOM 928 N NH2 . ARG A 1 172 ? -30.823 15.723 -40.759 1.00 86.96 ? 172 ARG A NH2 1 ATOM 929 N N . PRO A 1 173 ? -39.200 12.960 -41.859 1.00 83.54 ? 173 PRO A N 1 ATOM 930 C CA . PRO A 1 173 ? -40.416 12.858 -41.042 1.00 81.02 ? 173 PRO A CA 1 ATOM 931 C C . PRO A 1 173 ? -40.291 11.867 -39.891 1.00 74.19 ? 173 PRO A C 1 ATOM 932 O O . PRO A 1 173 ? -40.992 12.004 -38.887 1.00 72.13 ? 173 PRO A O 1 ATOM 933 C CB . PRO A 1 173 ? -41.467 12.364 -42.042 1.00 85.53 ? 173 PRO A CB 1 ATOM 934 C CG . PRO A 1 173 ? -40.964 12.810 -43.369 1.00 96.95 ? 173 PRO A CG 1 ATOM 935 C CD . PRO A 1 173 ? -39.473 12.682 -43.280 1.00 97.24 ? 173 PRO A CD 1 ATOM 936 N N . PHE A 1 174 ? -39.415 10.880 -40.042 1.00 72.60 ? 174 PHE A N 1 ATOM 937 C CA . PHE A 1 174 ? -39.190 9.891 -38.994 1.00 75.20 ? 174 PHE A CA 1 ATOM 938 C C . PHE A 1 174 ? -37.826 10.066 -38.336 1.00 71.31 ? 174 PHE A C 1 ATOM 939 O O . PHE A 1 174 ? -37.743 10.341 -37.139 1.00 69.18 ? 174 PHE A O 1 ATOM 940 C CB . PHE A 1 174 ? -39.381 8.472 -39.532 1.00 73.64 ? 174 PHE A CB 1 ATOM 941 C CG . PHE A 1 174 ? -40.822 8.098 -39.735 1.00 72.50 ? 174 PHE A CG 1 ATOM 942 C CD1 . PHE A 1 174 ? -41.818 8.716 -38.994 1.00 64.10 ? 174 PHE A CD1 1 ATOM 943 C CD2 . PHE A 1 174 ? -41.184 7.139 -40.666 1.00 69.85 ? 174 PHE A CD2 1 ATOM 944 C CE1 . PHE A 1 174 ? -43.144 8.384 -39.174 1.00 58.63 ? 174 PHE A CE1 1 ATOM 945 C CE2 . PHE A 1 174 ? -42.512 6.801 -40.851 1.00 62.10 ? 174 PHE A CE2 1 ATOM 946 C CZ . PHE A 1 174 ? -43.492 7.424 -40.104 1.00 61.00 ? 174 PHE A CZ 1 ATOM 947 N N . GLY A 1 175 ? -36.759 9.899 -39.111 1.00 67.30 ? 175 GLY A N 1 ATOM 948 C CA . GLY A 1 175 ? -35.423 10.140 -38.597 1.00 62.28 ? 175 GLY A CA 1 ATOM 949 C C . GLY A 1 175 ? -34.334 9.318 -39.256 1.00 61.82 ? 175 GLY A C 1 ATOM 950 O O . GLY A 1 175 ? -34.511 8.795 -40.355 1.00 69.15 ? 175 GLY A O 1 ATOM 951 N N . VAL A 1 176 ? -33.200 9.207 -38.574 1.00 61.64 ? 176 VAL A N 1 ATOM 952 C CA . VAL A 1 176 ? -32.059 8.457 -39.085 1.00 70.55 ? 176 VAL A CA 1 ATOM 953 C C . VAL A 1 176 ? -32.289 6.958 -38.908 1.00 62.53 ? 176 VAL A C 1 ATOM 954 O O . VAL A 1 176 ? -32.944 6.535 -37.959 1.00 52.18 ? 176 VAL A O 1 ATOM 955 C CB . VAL A 1 176 ? -30.764 8.858 -38.351 1.00 73.69 ? 176 VAL A CB 1 ATOM 956 C CG1 . VAL A 1 176 ? -29.535 8.440 -39.152 1.00 72.92 ? 176 VAL A CG1 1 ATOM 957 C CG2 . VAL A 1 176 ? -30.748 10.357 -38.091 1.00 76.57 ? 176 VAL A CG2 1 ATOM 958 N N . SER A 1 177 ? -31.762 6.158 -39.829 1.00 63.90 ? 177 SER A N 1 ATOM 959 C CA . SER A 1 177 ? -31.802 4.708 -39.689 1.00 59.98 ? 177 SER A CA 1 ATOM 960 C C . SER A 1 177 ? -30.388 4.157 -39.807 1.00 62.42 ? 177 SER A C 1 ATOM 961 O O . SER A 1 177 ? -29.621 4.596 -40.662 1.00 66.70 ? 177 SER A O 1 ATOM 962 C CB . SER A 1 177 ? -32.702 4.081 -40.754 1.00 64.70 ? 177 SER A CB 1 ATOM 963 O OG . SER A 1 177 ? -32.836 2.685 -40.545 1.00 70.55 ? 177 SER A OG 1 ATOM 964 N N . LEU A 1 178 ? -30.044 3.204 -38.944 1.00 59.98 ? 178 LEU A N 1 ATOM 965 C CA . LEU A 1 178 ? -28.701 2.625 -38.939 1.00 57.88 ? 178 LEU A CA 1 ATOM 966 C C . LEU A 1 178 ? -28.372 1.949 -40.270 1.00 59.26 ? 178 LEU A C 1 ATOM 967 O O . LEU A 1 178 ? -29.249 1.375 -40.914 1.00 59.76 ? 178 LEU A O 1 ATOM 968 C CB . LEU A 1 178 ? -28.530 1.655 -37.769 1.00 53.90 ? 178 LEU A CB 1 ATOM 969 C CG . LEU A 1 178 ? -28.431 2.332 -36.403 1.00 48.61 ? 178 LEU A CG 1 ATOM 970 C CD1 . LEU A 1 178 ? -28.233 1.315 -35.310 1.00 46.56 ? 178 LEU A CD1 1 ATOM 971 C CD2 . LEU A 1 178 ? -27.296 3.332 -36.387 1.00 54.46 ? 178 LEU A CD2 1 ATOM 972 N N . LEU A 1 179 ? -27.105 2.022 -40.669 1.00 56.62 ? 179 LEU A N 1 ATOM 973 C CA . LEU A 1 179 ? -26.695 1.679 -42.036 1.00 54.12 ? 179 LEU A CA 1 ATOM 974 C C . LEU A 1 179 ? -26.899 0.234 -42.516 1.00 54.04 ? 179 LEU A C 1 ATOM 975 O O . LEU A 1 179 ? -27.232 0.025 -43.684 1.00 61.83 ? 179 LEU A O 1 ATOM 976 C CB . LEU A 1 179 ? -25.265 2.146 -42.319 1.00 63.38 ? 179 LEU A CB 1 ATOM 977 C CG . LEU A 1 179 ? -25.061 2.745 -43.712 1.00 82.17 ? 179 LEU A CG 1 ATOM 978 C CD1 . LEU A 1 179 ? -26.151 3.767 -44.015 1.00 70.86 ? 179 LEU A CD1 1 ATOM 979 C CD2 . LEU A 1 179 ? -23.678 3.373 -43.840 1.00 90.63 ? 179 LEU A CD2 1 ATOM 980 N N . PRO A 1 180 ? -26.690 -0.769 -41.643 1.00 41.35 ? 180 PRO A N 1 ATOM 981 C CA . PRO A 1 180 ? -27.064 -2.108 -42.115 1.00 40.08 ? 180 PRO A CA 1 ATOM 982 C C . PRO A 1 180 ? -28.575 -2.165 -42.297 1.00 56.25 ? 180 PRO A C 1 ATOM 983 O O . PRO A 1 180 ? -29.280 -2.769 -41.490 1.00 59.92 ? 180 PRO A O 1 ATOM 984 C CB . PRO A 1 180 ? -26.639 -3.017 -40.961 1.00 32.40 ? 180 PRO A CB 1 ATOM 985 C CG . PRO A 1 180 ? -25.556 -2.266 -40.271 1.00 45.59 ? 180 PRO A CG 1 ATOM 986 C CD . PRO A 1 180 ? -25.940 -0.821 -40.377 1.00 47.88 ? 180 PRO A CD 1 ATOM 987 N N . ALA A 1 181 ? -29.049 -1.539 -43.372 1.00 57.97 ? 181 ALA A N 1 ATOM 988 C CA . ALA A 1 181 ? -30.454 -1.182 -43.544 1.00 46.00 ? 181 ALA A CA 1 ATOM 989 C C . ALA A 1 181 ? -31.392 -2.375 -43.641 1.00 39.64 ? 181 ALA A C 1 ATOM 990 O O . ALA A 1 181 ? -30.988 -3.475 -44.014 1.00 36.83 ? 181 ALA A O 1 ATOM 991 C CB . ALA A 1 181 ? -30.621 -0.281 -44.757 1.00 45.28 ? 181 ALA A CB 1 ATOM 992 N N . ARG A 1 182 ? -32.654 -2.130 -43.312 1.00 37.17 ? 182 ARG A N 1 ATOM 993 C CA . ARG A 1 182 ? -33.668 -3.172 -43.263 1.00 40.29 ? 182 ARG A CA 1 ATOM 994 C C . ARG A 1 182 ? -33.928 -3.786 -44.636 1.00 40.17 ? 182 ARG A C 1 ATOM 995 O O . ARG A 1 182 ? -34.184 -3.071 -45.604 1.00 38.44 ? 182 ARG A O 1 ATOM 996 C CB . ARG A 1 182 ? -34.965 -2.595 -42.701 1.00 48.35 ? 182 ARG A CB 1 ATOM 997 C CG . ARG A 1 182 ? -35.876 -3.623 -42.072 1.00 47.33 ? 182 ARG A CG 1 ATOM 998 C CD . ARG A 1 182 ? -37.207 -3.007 -41.716 1.00 39.15 ? 182 ARG A CD 1 ATOM 999 N NE . ARG A 1 182 ? -38.046 -3.934 -40.971 1.00 39.46 ? 182 ARG A NE 1 ATOM 1000 C CZ . ARG A 1 182 ? -39.349 -3.762 -40.787 1.00 44.47 ? 182 ARG A CZ 1 ATOM 1001 N NH1 . ARG A 1 182 ? -39.952 -2.703 -41.307 1.00 42.40 ? 182 ARG A NH1 1 ATOM 1002 N NH2 . ARG A 1 182 ? -40.048 -4.649 -40.094 1.00 47.12 ? 182 ARG A NH2 1 ATOM 1003 N N . PRO A 1 183 ? -33.869 -5.124 -44.719 1.00 42.11 ? 183 PRO A N 1 ATOM 1004 C CA . PRO A 1 183 ? -34.107 -5.843 -45.977 1.00 50.12 ? 183 PRO A CA 1 ATOM 1005 C C . PRO A 1 183 ? -35.547 -5.688 -46.471 1.00 47.78 ? 183 PRO A C 1 ATOM 1006 O O . PRO A 1 183 ? -36.481 -5.779 -45.677 1.00 51.31 ? 183 PRO A O 1 ATOM 1007 C CB . PRO A 1 183 ? -33.817 -7.303 -45.606 1.00 53.47 ? 183 PRO A CB 1 ATOM 1008 C CG . PRO A 1 183 ? -34.007 -7.371 -44.126 1.00 45.48 ? 183 PRO A CG 1 ATOM 1009 C CD . PRO A 1 183 ? -33.572 -6.038 -43.601 1.00 40.77 ? 183 PRO A CD 1 ATOM 1010 N N . THR A 1 184 ? -35.719 -5.457 -47.770 1.00 49.57 ? 184 THR A N 1 ATOM 1011 C CA . THR A 1 184 ? -37.048 -5.261 -48.346 1.00 55.92 ? 184 THR A CA 1 ATOM 1012 C C . THR A 1 184 ? -37.811 -6.584 -48.444 1.00 52.89 ? 184 THR A C 1 ATOM 1013 O O . THR A 1 184 ? -37.203 -7.654 -48.504 1.00 57.60 ? 184 THR A O 1 ATOM 1014 C CB . THR A 1 184 ? -36.955 -4.609 -49.742 1.00 67.07 ? 184 THR A CB 1 ATOM 1015 O OG1 . THR A 1 184 ? -35.949 -3.589 -49.726 1.00 73.85 ? 184 THR A OG1 1 ATOM 1016 C CG2 . THR A 1 184 ? -38.288 -3.991 -50.149 1.00 56.50 ? 184 THR A CG2 1 ATOM 1017 N N . VAL A 1 185 ? -39.139 -6.503 -48.445 1.00 44.66 ? 185 VAL A N 1 ATOM 1018 C CA . VAL A 1 185 ? -39.994 -7.678 -48.577 1.00 42.70 ? 185 VAL A CA 1 ATOM 1019 C C . VAL A 1 185 ? -39.707 -8.379 -49.896 1.00 47.84 ? 185 VAL A C 1 ATOM 1020 O O . VAL A 1 185 ? -39.534 -7.720 -50.920 1.00 50.60 ? 185 VAL A O 1 ATOM 1021 C CB . VAL A 1 185 ? -41.480 -7.280 -48.571 1.00 38.84 ? 185 VAL A CB 1 ATOM 1022 C CG1 . VAL A 1 185 ? -42.336 -8.408 -48.019 1.00 31.90 ? 185 VAL A CG1 1 ATOM 1023 C CG2 . VAL A 1 185 ? -41.685 -6.012 -47.762 1.00 40.18 ? 185 VAL A CG2 1 ATOM 1024 N N . PRO A 1 186 ? -39.639 -9.720 -49.877 1.00 52.23 ? 186 PRO A N 1 ATOM 1025 C CA . PRO A 1 186 ? -39.495 -10.467 -51.133 1.00 60.12 ? 186 PRO A CA 1 ATOM 1026 C C . PRO A 1 186 ? -40.709 -10.247 -52.033 1.00 59.22 ? 186 PRO A C 1 ATOM 1027 O O . PRO A 1 186 ? -41.843 -10.385 -51.575 1.00 60.91 ? 186 PRO A O 1 ATOM 1028 C CB . PRO A 1 186 ? -39.425 -11.926 -50.667 1.00 65.02 ? 186 PRO A CB 1 ATOM 1029 C CG . PRO A 1 186 ? -40.034 -11.929 -49.294 1.00 54.89 ? 186 PRO A CG 1 ATOM 1030 C CD . PRO A 1 186 ? -39.659 -10.609 -48.703 1.00 48.12 ? 186 PRO A CD 1 ATOM 1031 N N . LYS A 1 187 ? -40.474 -9.913 -53.298 1.00 53.73 ? 187 LYS A N 1 ATOM 1032 C CA . LYS A 1 187 ? -41.558 -9.517 -54.193 1.00 53.26 ? 187 LYS A CA 1 ATOM 1033 C C . LYS A 1 187 ? -42.551 -10.640 -54.489 1.00 63.89 ? 187 LYS A C 1 ATOM 1034 O O . LYS A 1 187 ? -43.760 -10.445 -54.392 1.00 67.98 ? 187 LYS A O 1 ATOM 1035 C CB . LYS A 1 187 ? -41.000 -8.939 -55.485 1.00 53.49 ? 187 LYS A CB 1 ATOM 1036 N N . ASN A 1 188 ? -42.046 -11.812 -54.856 1.00 68.90 ? 188 ASN A N 1 ATOM 1037 C CA . ASN A 1 188 ? -42.925 -12.908 -55.252 1.00 63.97 ? 188 ASN A CA 1 ATOM 1038 C C . ASN A 1 188 ? -43.243 -13.902 -54.130 1.00 65.10 ? 188 ASN A C 1 ATOM 1039 O O . ASN A 1 188 ? -43.990 -14.855 -54.344 1.00 68.71 ? 188 ASN A O 1 ATOM 1040 C CB . ASN A 1 188 ? -42.351 -13.638 -56.464 1.00 60.25 ? 188 ASN A CB 1 ATOM 1041 N N . THR A 1 189 ? -42.697 -13.686 -52.937 1.00 55.35 ? 189 THR A N 1 ATOM 1042 C CA . THR A 1 189 ? -42.866 -14.662 -51.862 1.00 51.61 ? 189 THR A CA 1 ATOM 1043 C C . THR A 1 189 ? -44.087 -14.403 -50.985 1.00 51.04 ? 189 THR A C 1 ATOM 1044 O O . THR A 1 189 ? -44.801 -13.417 -51.166 1.00 52.21 ? 189 THR A O 1 ATOM 1045 C CB . THR A 1 189 ? -41.617 -14.732 -51.010 1.00 64.20 ? 189 THR A CB 1 ATOM 1046 N N . ILE A 1 190 ? -44.302 -15.294 -50.021 1.00 55.46 ? 190 ILE A N 1 ATOM 1047 C CA . ILE A 1 190 ? -45.448 -15.210 -49.123 1.00 61.27 ? 190 ILE A CA 1 ATOM 1048 C C . ILE A 1 190 ? -45.001 -14.870 -47.704 1.00 65.21 ? 190 ILE A C 1 ATOM 1049 O O . ILE A 1 190 ? -44.112 -15.521 -47.155 1.00 71.07 ? 190 ILE A O 1 ATOM 1050 C CB . ILE A 1 190 ? -46.210 -16.549 -49.066 1.00 57.24 ? 190 ILE A CB 1 ATOM 1051 C CG1 . ILE A 1 190 ? -45.853 -17.427 -50.269 1.00 58.46 ? 190 ILE A CG1 1 ATOM 1052 C CG2 . ILE A 1 190 ? -47.713 -16.313 -48.971 1.00 58.90 ? 190 ILE A CG2 1 ATOM 1053 C CD1 . ILE A 1 190 ? -46.476 -18.806 -50.219 1.00 70.35 ? 190 ILE A CD1 1 ATOM 1054 N N . LEU A 1 191 ? -45.615 -13.852 -47.107 1.00 58.04 ? 191 LEU A N 1 ATOM 1055 C CA . LEU A 1 191 ? -45.328 -13.531 -45.715 1.00 48.67 ? 191 LEU A CA 1 ATOM 1056 C C . LEU A 1 191 ? -46.074 -14.505 -44.820 1.00 51.61 ? 191 LEU A C 1 ATOM 1057 O O . LEU A 1 191 ? -47.295 -14.623 -44.908 1.00 64.46 ? 191 LEU A O 1 ATOM 1058 C CB . LEU A 1 191 ? -45.741 -12.096 -45.380 1.00 43.65 ? 191 LEU A CB 1 ATOM 1059 C CG . LEU A 1 191 ? -45.002 -10.976 -46.113 1.00 42.81 ? 191 LEU A CG 1 ATOM 1060 C CD1 . LEU A 1 191 ? -45.208 -9.640 -45.412 1.00 40.15 ? 191 LEU A CD1 1 ATOM 1061 C CD2 . LEU A 1 191 ? -43.525 -11.303 -46.238 1.00 49.67 ? 191 LEU A CD2 1 ATOM 1062 N N . GLU A 1 192 ? -45.341 -15.211 -43.966 1.00 49.80 ? 192 GLU A N 1 ATOM 1063 C CA . GLU A 1 192 ? -45.967 -16.110 -43.005 1.00 51.87 ? 192 GLU A CA 1 ATOM 1064 C C . GLU A 1 192 ? -46.762 -15.303 -41.988 1.00 42.87 ? 192 GLU A C 1 ATOM 1065 O O . GLU A 1 192 ? -46.440 -14.147 -41.713 1.00 39.64 ? 192 GLU A O 1 ATOM 1066 C CB . GLU A 1 192 ? -44.919 -16.980 -42.304 1.00 62.66 ? 192 GLU A CB 1 ATOM 1067 C CG . GLU A 1 192 ? -44.459 -18.191 -43.111 1.00 63.82 ? 192 GLU A CG 1 ATOM 1068 C CD . GLU A 1 192 ? -45.499 -19.299 -43.152 1.00 70.44 ? 192 GLU A CD 1 ATOM 1069 O OE1 . GLU A 1 192 ? -46.488 -19.219 -42.392 1.00 58.97 ? 192 GLU A OE1 1 ATOM 1070 O OE2 . GLU A 1 192 ? -45.326 -20.252 -43.941 1.00 76.13 ? 192 GLU A OE2 1 ATOM 1071 N N . HIS A 1 193 ? -47.812 -15.902 -41.441 1.00 43.13 ? 193 HIS A N 1 ATOM 1072 C CA . HIS A 1 193 ? -48.631 -15.210 -40.459 1.00 52.59 ? 193 HIS A CA 1 ATOM 1073 C C . HIS A 1 193 ? -47.818 -14.957 -39.195 1.00 54.45 ? 193 HIS A C 1 ATOM 1074 O O . HIS A 1 193 ? -47.988 -13.935 -38.530 1.00 58.25 ? 193 HIS A O 1 ATOM 1075 C CB . HIS A 1 193 ? -49.885 -16.013 -40.148 1.00 56.50 ? 193 HIS A CB 1 ATOM 1076 N N . LYS A 1 194 ? -46.926 -15.892 -38.881 1.00 53.26 ? 194 LYS A N 1 ATOM 1077 C CA . LYS A 1 194 ? -46.073 -15.792 -37.701 1.00 52.88 ? 194 LYS A CA 1 ATOM 1078 C C . LYS A 1 194 ? -44.621 -16.124 -38.025 1.00 55.11 ? 194 LYS A C 1 ATOM 1079 O O . LYS A 1 194 ? -44.319 -16.687 -39.077 1.00 61.10 ? 194 LYS A O 1 ATOM 1080 C CB . LYS A 1 194 ? -46.564 -16.736 -36.602 1.00 52.07 ? 194 LYS A CB 1 ATOM 1081 C CG . LYS A 1 194 ? -47.683 -16.187 -35.733 1.00 47.86 ? 194 LYS A CG 1 ATOM 1082 C CD . LYS A 1 194 ? -48.021 -17.168 -34.618 1.00 49.96 ? 194 LYS A CD 1 ATOM 1083 C CE . LYS A 1 194 ? -48.861 -16.514 -33.534 1.00 53.71 ? 194 LYS A CE 1 ATOM 1084 N NZ . LYS A 1 194 ? -49.096 -17.439 -32.390 1.00 57.23 ? 194 LYS A NZ 1 ATOM 1085 N N . ALA A 1 195 ? -43.723 -15.777 -37.110 1.00 52.39 ? 195 ALA A N 1 ATOM 1086 C CA . ALA A 1 195 ? -42.316 -16.126 -37.251 1.00 52.61 ? 195 ALA A CA 1 ATOM 1087 C C . ALA A 1 195 ? -42.111 -17.612 -36.979 1.00 54.94 ? 195 ALA A C 1 ATOM 1088 O O . ALA A 1 195 ? -42.723 -18.172 -36.071 1.00 59.26 ? 195 ALA A O 1 ATOM 1089 C CB . ALA A 1 195 ? -41.477 -15.300 -36.305 1.00 54.40 ? 195 ALA A CB 1 ATOM 1090 N N . HIS A 1 196 ? -41.245 -18.244 -37.765 1.00 54.08 ? 196 HIS A N 1 ATOM 1091 C CA . HIS A 1 196 ? -40.984 -19.674 -37.637 1.00 58.34 ? 196 HIS A CA 1 ATOM 1092 C C . HIS A 1 196 ? -39.561 -20.011 -38.062 1.00 62.89 ? 196 HIS A C 1 ATOM 1093 O O . HIS A 1 196 ? -38.949 -19.272 -38.833 1.00 68.66 ? 196 HIS A O 1 ATOM 1094 C CB . HIS A 1 196 ? -41.943 -20.472 -38.525 1.00 63.40 ? 196 HIS A CB 1 ATOM 1095 C CG . HIS A 1 196 ? -43.326 -20.613 -37.968 1.00 62.85 ? 196 HIS A CG 1 ATOM 1096 N ND1 . HIS A 1 196 ? -44.249 -19.589 -37.992 1.00 62.53 ? 196 HIS A ND1 1 ATOM 1097 C CD2 . HIS A 1 196 ? -43.950 -21.668 -37.394 1.00 62.40 ? 196 HIS A CD2 1 ATOM 1098 C CE1 . HIS A 1 196 ? -45.378 -20.004 -37.445 1.00 64.31 ? 196 HIS A CE1 1 ATOM 1099 N NE2 . HIS A 1 196 ? -45.223 -21.262 -37.074 1.00 64.68 ? 196 HIS A NE2 1 ATOM 1100 N N . PHE A 1 197 ? -39.025 -21.108 -37.535 1.00 63.65 ? 197 PHE A N 1 ATOM 1101 C CA . PHE A 1 197 ? -37.869 -21.762 -38.149 1.00 79.86 ? 197 PHE A CA 1 ATOM 1102 C C . PHE A 1 197 ? -38.004 -23.285 -38.138 1.00 81.02 ? 197 PHE A C 1 ATOM 1103 O O . PHE A 1 197 ? -38.156 -23.901 -37.082 1.00 81.14 ? 197 PHE A O 1 ATOM 1104 C CB . PHE A 1 197 ? -36.533 -21.301 -37.541 1.00 85.55 ? 197 PHE A CB 1 ATOM 1105 C CG . PHE A 1 197 ? -36.548 -21.157 -36.044 1.00 83.64 ? 197 PHE A CG 1 ATOM 1106 C CD1 . PHE A 1 197 ? -36.337 -22.252 -35.223 1.00 77.60 ? 197 PHE A CD1 1 ATOM 1107 C CD2 . PHE A 1 197 ? -36.742 -19.916 -35.458 1.00 75.58 ? 197 PHE A CD2 1 ATOM 1108 C CE1 . PHE A 1 197 ? -36.342 -22.117 -33.847 1.00 70.49 ? 197 PHE A CE1 1 ATOM 1109 C CE2 . PHE A 1 197 ? -36.745 -19.774 -34.084 1.00 62.47 ? 197 PHE A CE2 1 ATOM 1110 C CZ . PHE A 1 197 ? -36.546 -20.875 -33.278 1.00 67.22 ? 197 PHE A CZ 1 ATOM 1111 N N . ALA A 1 198 ? -37.998 -23.883 -39.324 1.00 82.75 ? 198 ALA A N 1 ATOM 1112 C CA . ALA A 1 198 ? -37.997 -25.335 -39.445 1.00 87.72 ? 198 ALA A CA 1 ATOM 1113 C C . ALA A 1 198 ? -36.590 -25.858 -39.710 1.00 80.84 ? 198 ALA A C 1 ATOM 1114 O O . ALA A 1 198 ? -36.374 -27.068 -39.789 1.00 82.24 ? 198 ALA A O 1 ATOM 1115 C CB . ALA A 1 198 ? -38.948 -25.778 -40.545 1.00 103.72 ? 198 ALA A CB 1 ATOM 1116 N N . THR A 1 199 ? -35.633 -24.943 -39.841 1.00 79.69 ? 199 THR A N 1 ATOM 1117 C CA . THR A 1 199 ? -34.279 -25.315 -40.239 1.00 86.55 ? 199 THR A CA 1 ATOM 1118 C C . THR A 1 199 ? -33.214 -24.374 -39.680 1.00 84.45 ? 199 THR A C 1 ATOM 1119 O O . THR A 1 199 ? -33.518 -23.268 -39.231 1.00 83.80 ? 199 THR A O 1 ATOM 1120 C CB . THR A 1 199 ? -34.147 -25.376 -41.776 1.00 84.71 ? 199 THR A CB 1 ATOM 1121 O OG1 . THR A 1 199 ? -32.808 -25.740 -42.132 1.00 82.12 ? 199 THR A OG1 1 ATOM 1122 C CG2 . THR A 1 199 ? -34.484 -24.030 -42.397 1.00 83.71 ? 199 THR A CG2 1 ATOM 1123 N N . TRP A 1 200 ? -31.964 -24.826 -39.709 1.00 84.21 ? 200 TRP A N 1 ATOM 1124 C CA . TRP A 1 200 ? -30.839 -24.020 -39.245 1.00 85.15 ? 200 TRP A CA 1 ATOM 1125 C C . TRP A 1 200 ? -30.519 -22.896 -40.219 1.00 78.60 ? 200 TRP A C 1 ATOM 1126 O O . TRP A 1 200 ? -29.981 -21.859 -39.834 1.00 78.70 ? 200 TRP A O 1 ATOM 1127 C CB . TRP A 1 200 ? -29.601 -24.894 -39.018 1.00 87.97 ? 200 TRP A CB 1 ATOM 1128 C CG . TRP A 1 200 ? -29.707 -25.744 -37.796 1.00 83.49 ? 200 TRP A CG 1 ATOM 1129 C CD1 . TRP A 1 200 ? -29.619 -27.104 -37.726 1.00 86.77 ? 200 TRP A CD1 1 ATOM 1130 C CD2 . TRP A 1 200 ? -29.941 -25.287 -36.462 1.00 74.43 ? 200 TRP A CD2 1 ATOM 1131 N NE1 . TRP A 1 200 ? -29.776 -27.520 -36.425 1.00 85.17 ? 200 TRP A NE1 1 ATOM 1132 C CE2 . TRP A 1 200 ? -29.976 -26.422 -35.631 1.00 78.39 ? 200 TRP A CE2 1 ATOM 1133 C CE3 . TRP A 1 200 ? -30.121 -24.025 -35.889 1.00 67.79 ? 200 TRP A CE3 1 ATOM 1134 C CZ2 . TRP A 1 200 ? -30.185 -26.331 -34.258 1.00 77.29 ? 200 TRP A CZ2 1 ATOM 1135 C CZ3 . TRP A 1 200 ? -30.328 -23.938 -34.533 1.00 71.42 ? 200 TRP A CZ3 1 ATOM 1136 C CH2 . TRP A 1 200 ? -30.359 -25.082 -33.731 1.00 75.25 ? 200 TRP A CH2 1 ATOM 1137 N N . ASP A 1 201 ? -30.855 -23.113 -41.484 1.00 75.01 ? 201 ASP A N 1 ATOM 1138 C CA . ASP A 1 201 ? -30.640 -22.112 -42.517 1.00 81.47 ? 201 ASP A CA 1 ATOM 1139 C C . ASP A 1 201 ? -31.514 -20.889 -42.252 1.00 80.26 ? 201 ASP A C 1 ATOM 1140 O O . ASP A 1 201 ? -31.162 -19.770 -42.626 1.00 82.30 ? 201 ASP A O 1 ATOM 1141 C CB . ASP A 1 201 ? -30.948 -22.710 -43.893 1.00 89.47 ? 201 ASP A CB 1 ATOM 1142 C CG . ASP A 1 201 ? -30.465 -21.838 -45.035 1.00 89.51 ? 201 ASP A CG 1 ATOM 1143 O OD1 . ASP A 1 201 ? -29.495 -21.076 -44.840 1.00 88.12 ? 201 ASP A OD1 1 ATOM 1144 O OD2 . ASP A 1 201 ? -31.053 -21.923 -46.134 1.00 88.96 ? 201 ASP A OD2 1 ATOM 1145 N N . ALA A 1 202 ? -32.642 -21.107 -41.583 1.00 78.58 ? 202 ALA A N 1 ATOM 1146 C CA . ALA A 1 202 ? -33.612 -20.044 -41.327 1.00 83.24 ? 202 ALA A CA 1 ATOM 1147 C C . ALA A 1 202 ? -33.086 -18.937 -40.412 1.00 77.45 ? 202 ALA A C 1 ATOM 1148 O O . ALA A 1 202 ? -33.420 -17.766 -40.595 1.00 79.16 ? 202 ALA A O 1 ATOM 1149 C CB . ALA A 1 202 ? -34.895 -20.632 -40.753 1.00 88.77 ? 202 ALA A CB 1 ATOM 1150 N N . LEU A 1 203 ? -32.268 -19.307 -39.432 1.00 79.44 ? 203 LEU A N 1 ATOM 1151 C CA . LEU A 1 203 ? -31.751 -18.347 -38.460 1.00 81.17 ? 203 LEU A CA 1 ATOM 1152 C C . LEU A 1 203 ? -30.663 -17.450 -39.053 1.00 79.78 ? 203 LEU A C 1 ATOM 1153 O O . LEU A 1 203 ? -30.308 -16.423 -38.471 1.00 74.42 ? 203 LEU A O 1 ATOM 1154 C CB . LEU A 1 203 ? -31.227 -19.071 -37.217 1.00 75.33 ? 203 LEU A CB 1 ATOM 1155 C CG . LEU A 1 203 ? -32.266 -19.869 -36.425 1.00 69.83 ? 203 LEU A CG 1 ATOM 1156 C CD1 . LEU A 1 203 ? -31.622 -20.605 -35.261 1.00 63.11 ? 203 LEU A CD1 1 ATOM 1157 C CD2 . LEU A 1 203 ? -33.366 -18.951 -35.930 1.00 62.09 ? 203 LEU A CD2 1 ATOM 1158 N N . ALA A 1 204 ? -30.140 -17.841 -40.211 1.00 76.78 ? 204 ALA A N 1 ATOM 1159 C CA . ALA A 1 204 ? -29.114 -17.060 -40.893 1.00 74.80 ? 204 ALA A CA 1 ATOM 1160 C C . ALA A 1 204 ? -29.731 -16.108 -41.913 1.00 70.08 ? 204 ALA A C 1 ATOM 1161 O O . ALA A 1 204 ? -29.666 -14.888 -41.753 1.00 65.00 ? 204 ALA A O 1 ATOM 1162 C CB . ALA A 1 204 ? -28.107 -17.979 -41.564 1.00 85.41 ? 204 ALA A CB 1 ATOM 1163 N N . ARG A 1 205 ? -30.319 -16.674 -42.965 1.00 72.57 ? 205 ARG A N 1 ATOM 1164 C CA . ARG A 1 205 ? -31.030 -15.889 -43.969 1.00 80.51 ? 205 ARG A CA 1 ATOM 1165 C C . ARG A 1 205 ? -32.141 -15.083 -43.312 1.00 72.08 ? 205 ARG A C 1 ATOM 1166 O O . ARG A 1 205 ? -32.749 -15.534 -42.341 1.00 71.93 ? 205 ARG A O 1 ATOM 1167 C CB . ARG A 1 205 ? -31.653 -16.798 -45.031 1.00 94.38 ? 205 ARG A CB 1 ATOM 1168 C CG . ARG A 1 205 ? -30.700 -17.342 -46.084 1.00 95.26 ? 205 ARG A CG 1 ATOM 1169 C CD . ARG A 1 205 ? -31.502 -17.949 -47.230 1.00 98.95 ? 205 ARG A CD 1 ATOM 1170 N NE . ARG A 1 205 ? -30.668 -18.649 -48.202 1.00 110.10 ? 205 ARG A NE 1 ATOM 1171 C CZ . ARG A 1 205 ? -31.139 -19.246 -49.293 1.00 119.16 ? 205 ARG A CZ 1 ATOM 1172 N NH1 . ARG A 1 205 ? -32.439 -19.225 -49.557 1.00 119.47 ? 205 ARG A NH1 1 ATOM 1173 N NH2 . ARG A 1 205 ? -30.310 -19.863 -50.124 1.00 119.48 ? 205 ARG A NH2 1 ATOM 1174 N N . HIS A 1 206 ? -32.404 -13.893 -43.840 1.00 67.63 ? 206 HIS A N 1 ATOM 1175 C CA . HIS A 1 206 ? -33.520 -13.098 -43.355 1.00 64.30 ? 206 HIS A CA 1 ATOM 1176 C C . HIS A 1 206 ? -34.823 -13.855 -43.587 1.00 63.89 ? 206 HIS A C 1 ATOM 1177 O O . HIS A 1 206 ? -35.119 -14.272 -44.707 1.00 64.66 ? 206 HIS A O 1 ATOM 1178 C CB . HIS A 1 206 ? -33.570 -11.746 -44.069 1.00 62.89 ? 206 HIS A CB 1 ATOM 1179 C CG . HIS A 1 206 ? -32.359 -10.894 -43.844 1.00 64.63 ? 206 HIS A CG 1 ATOM 1180 N ND1 . HIS A 1 206 ? -31.904 -9.990 -44.780 1.00 68.82 ? 206 HIS A ND1 1 ATOM 1181 C CD2 . HIS A 1 206 ? -31.515 -10.801 -42.790 1.00 69.51 ? 206 HIS A CD2 1 ATOM 1182 C CE1 . HIS A 1 206 ? -30.829 -9.381 -44.314 1.00 74.06 ? 206 HIS A CE1 1 ATOM 1183 N NE2 . HIS A 1 206 ? -30.571 -9.854 -43.109 1.00 78.83 ? 206 HIS A NE2 1 ATOM 1184 N N . THR A 1 207 ? -35.592 -14.041 -42.522 1.00 61.39 ? 207 THR A N 1 ATOM 1185 C CA . THR A 1 207 ? -36.897 -14.677 -42.627 1.00 55.58 ? 207 THR A CA 1 ATOM 1186 C C . THR A 1 207 ? -37.956 -13.658 -42.238 1.00 52.85 ? 207 THR A C 1 ATOM 1187 O O . THR A 1 207 ? -37.814 -12.958 -41.233 1.00 50.39 ? 207 THR A O 1 ATOM 1188 C CB . THR A 1 207 ? -36.997 -15.934 -41.738 1.00 55.08 ? 207 THR A CB 1 ATOM 1189 O OG1 . THR A 1 207 ? -35.948 -16.846 -42.084 1.00 66.80 ? 207 THR A OG1 1 ATOM 1190 C CG2 . THR A 1 207 ? -38.339 -16.628 -41.928 1.00 45.53 ? 207 THR A CG2 1 ATOM 1191 N N . PHE A 1 208 ? -39.010 -13.572 -43.041 1.00 52.62 ? 208 PHE A N 1 ATOM 1192 C CA . PHE A 1 208 ? -40.028 -12.545 -42.860 1.00 48.84 ? 208 PHE A CA 1 ATOM 1193 C C . PHE A 1 208 ? -41.352 -13.130 -42.382 1.00 44.34 ? 208 PHE A C 1 ATOM 1194 O O . PHE A 1 208 ? -41.675 -14.284 -42.667 1.00 41.66 ? 208 PHE A O 1 ATOM 1195 C CB . PHE A 1 208 ? -40.261 -11.795 -44.172 1.00 44.81 ? 208 PHE A CB 1 ATOM 1196 C CG . PHE A 1 208 ? -39.016 -11.207 -44.772 1.00 41.98 ? 208 PHE A CG 1 ATOM 1197 C CD1 . PHE A 1 208 ? -38.234 -11.948 -45.644 1.00 48.74 ? 208 PHE A CD1 1 ATOM 1198 C CD2 . PHE A 1 208 ? -38.639 -9.907 -44.482 1.00 40.56 ? 208 PHE A CD2 1 ATOM 1199 C CE1 . PHE A 1 208 ? -37.093 -11.408 -46.204 1.00 52.16 ? 208 PHE A CE1 1 ATOM 1200 C CE2 . PHE A 1 208 ? -37.501 -9.360 -45.041 1.00 47.95 ? 208 PHE A CE2 1 ATOM 1201 C CZ . PHE A 1 208 ? -36.726 -10.112 -45.902 1.00 50.35 ? 208 PHE A CZ 1 ATOM 1202 N N . PHE A 1 209 ? -42.112 -12.327 -41.644 1.00 40.26 ? 209 PHE A N 1 ATOM 1203 C CA . PHE A 1 209 ? -43.481 -12.690 -41.293 1.00 50.34 ? 209 PHE A CA 1 ATOM 1204 C C . PHE A 1 209 ? -44.393 -11.462 -41.233 1.00 51.16 ? 209 PHE A C 1 ATOM 1205 O O . PHE A 1 209 ? -43.919 -10.328 -41.142 1.00 45.51 ? 209 PHE A O 1 ATOM 1206 C CB . PHE A 1 209 ? -43.537 -13.528 -40.008 1.00 49.92 ? 209 PHE A CB 1 ATOM 1207 C CG . PHE A 1 209 ? -43.338 -12.743 -38.744 1.00 47.04 ? 209 PHE A CG 1 ATOM 1208 C CD1 . PHE A 1 209 ? -42.065 -12.435 -38.296 1.00 47.13 ? 209 PHE A CD1 1 ATOM 1209 C CD2 . PHE A 1 209 ? -44.426 -12.343 -37.986 1.00 45.53 ? 209 PHE A CD2 1 ATOM 1210 C CE1 . PHE A 1 209 ? -41.882 -11.727 -37.124 1.00 45.58 ? 209 PHE A CE1 1 ATOM 1211 C CE2 . PHE A 1 209 ? -44.251 -11.633 -36.816 1.00 41.09 ? 209 PHE A CE2 1 ATOM 1212 C CZ . PHE A 1 209 ? -42.978 -11.324 -36.384 1.00 42.19 ? 209 PHE A CZ 1 ATOM 1213 N N . SER A 1 210 ? -45.701 -11.700 -41.301 1.00 50.98 ? 210 SER A N 1 ATOM 1214 C CA . SER A 1 210 ? -46.682 -10.632 -41.484 1.00 48.45 ? 210 SER A CA 1 ATOM 1215 C C . SER A 1 210 ? -46.940 -9.801 -40.230 1.00 45.44 ? 210 SER A C 1 ATOM 1216 O O . SER A 1 210 ? -46.777 -10.283 -39.111 1.00 48.89 ? 210 SER A O 1 ATOM 1217 C CB . SER A 1 210 ? -48.003 -11.217 -41.991 1.00 56.12 ? 210 SER A CB 1 ATOM 1218 O OG . SER A 1 210 ? -48.988 -10.207 -42.148 1.00 61.86 ? 210 SER A OG 1 ATOM 1219 N N . ALA A 1 211 ? -47.351 -8.552 -40.435 1.00 39.51 ? 211 ALA A N 1 ATOM 1220 C CA . ALA A 1 211 ? -47.730 -7.661 -39.343 1.00 42.25 ? 211 ALA A CA 1 ATOM 1221 C C . ALA A 1 211 ? -49.224 -7.756 -39.032 1.00 47.30 ? 211 ALA A C 1 ATOM 1222 O O . ALA A 1 211 ? -49.749 -6.980 -38.233 1.00 48.16 ? 211 ALA A O 1 ATOM 1223 C CB . ALA A 1 211 ? -47.339 -6.225 -39.660 1.00 37.80 ? 211 ALA A CB 1 ATOM 1224 N N . GLU A 1 212 ? -49.898 -8.711 -39.671 1.00 50.60 ? 212 GLU A N 1 ATOM 1225 C CA . GLU A 1 212 ? -51.352 -8.865 -39.571 1.00 55.58 ? 212 GLU A CA 1 ATOM 1226 C C . GLU A 1 212 ? -51.845 -9.101 -38.140 1.00 52.83 ? 212 GLU A C 1 ATOM 1227 O O . GLU A 1 212 ? -53.047 -9.044 -37.870 1.00 52.58 ? 212 GLU A O 1 ATOM 1228 C CB . GLU A 1 212 ? -51.843 -9.986 -40.503 1.00 63.32 ? 212 GLU A CB 1 ATOM 1229 C CG . GLU A 1 212 ? -51.474 -11.395 -40.058 1.00 63.98 ? 212 GLU A CG 1 ATOM 1230 C CD . GLU A 1 212 ? -51.856 -12.460 -41.076 1.00 67.75 ? 212 GLU A CD 1 ATOM 1231 O OE1 . GLU A 1 212 ? -52.296 -13.552 -40.657 1.00 67.76 ? 212 GLU A OE1 1 ATOM 1232 O OE2 . GLU A 1 212 ? -51.707 -12.211 -42.292 1.00 58.15 ? 212 GLU A OE2 1 ATOM 1233 N N . ALA A 1 213 ? -50.917 -9.371 -37.229 1.00 49.58 ? 213 ALA A N 1 ATOM 1234 C CA . ALA A 1 213 ? -51.248 -9.478 -35.816 1.00 44.78 ? 213 ALA A CA 1 ATOM 1235 C C . ALA A 1 213 ? -51.804 -8.161 -35.273 1.00 41.43 ? 213 ALA A C 1 ATOM 1236 O O . ALA A 1 213 ? -52.690 -8.161 -34.419 1.00 44.33 ? 213 ALA A O 1 ATOM 1237 C CB . ALA A 1 213 ? -50.022 -9.903 -35.025 1.00 44.00 ? 213 ALA A CB 1 ATOM 1238 N N . ILE A 1 214 ? -51.285 -7.045 -35.781 1.00 39.90 ? 214 ILE A N 1 ATOM 1239 C CA . ILE A 1 214 ? -51.686 -5.715 -35.321 1.00 38.15 ? 214 ILE A CA 1 ATOM 1240 C C . ILE A 1 214 ? -53.104 -5.321 -35.757 1.00 44.52 ? 214 ILE A C 1 ATOM 1241 O O . ILE A 1 214 ? -53.825 -4.668 -35.008 1.00 46.74 ? 214 ILE A O 1 ATOM 1242 C CB . ILE A 1 214 ? -50.681 -4.622 -35.787 1.00 33.18 ? 214 ILE A CB 1 ATOM 1243 C CG1 . ILE A 1 214 ? -49.246 -5.019 -35.443 1.00 25.37 ? 214 ILE A CG1 1 ATOM 1244 C CG2 . ILE A 1 214 ? -51.005 -3.268 -35.164 1.00 28.93 ? 214 ILE A CG2 1 ATOM 1245 C CD1 . ILE A 1 214 ? -48.249 -3.909 -35.685 1.00 22.30 ? 214 ILE A CD1 1 ATOM 1246 N N . ILE A 1 215 ? -53.507 -5.710 -36.964 1.00 48.87 ? 215 ILE A N 1 ATOM 1247 C CA . ILE A 1 215 ? -54.824 -5.312 -37.473 1.00 51.23 ? 215 ILE A CA 1 ATOM 1248 C C . ILE A 1 215 ? -55.957 -6.117 -36.831 1.00 40.15 ? 215 ILE A C 1 ATOM 1249 O O . ILE A 1 215 ? -57.059 -5.606 -36.634 1.00 33.54 ? 215 ILE A O 1 ATOM 1250 C CB . ILE A 1 215 ? -54.898 -5.368 -39.027 1.00 51.79 ? 215 ILE A CB 1 ATOM 1251 C CG1 . ILE A 1 215 ? -56.195 -4.732 -39.537 1.00 51.73 ? 215 ILE A CG1 1 ATOM 1252 C CG2 . ILE A 1 215 ? -54.758 -6.797 -39.538 1.00 45.55 ? 215 ILE A CG2 1 ATOM 1253 C CD1 . ILE A 1 215 ? -56.417 -3.313 -39.055 1.00 55.35 ? 215 ILE A CD1 1 ATOM 1254 N N . THR A 1 216 ? -55.668 -7.368 -36.483 1.00 37.82 ? 216 THR A N 1 ATOM 1255 C CA . THR A 1 216 ? -56.658 -8.249 -35.875 1.00 40.71 ? 216 THR A CA 1 ATOM 1256 C C . THR A 1 216 ? -56.552 -8.263 -34.354 1.00 52.07 ? 216 THR A C 1 ATOM 1257 O O . THR A 1 216 ? -57.463 -7.818 -33.656 1.00 62.84 ? 216 THR A O 1 ATOM 1258 C CB . THR A 1 216 ? -56.523 -9.697 -36.383 1.00 39.65 ? 216 THR A CB 1 ATOM 1259 O OG1 . THR A 1 216 ? -55.430 -10.341 -35.720 1.00 45.97 ? 216 THR A OG1 1 ATOM 1260 C CG2 . THR A 1 216 ? -56.288 -9.715 -37.878 1.00 46.03 ? 216 THR A CG2 1 ATOM 1261 N N . ASN A 1 217 ? -55.421 -8.750 -33.852 1.00 48.45 ? 217 ASN A N 1 ATOM 1262 C CA . ASN A 1 217 ? -55.261 -9.088 -32.438 1.00 41.34 ? 217 ASN A CA 1 ATOM 1263 C C . ASN A 1 217 ? -54.945 -7.907 -31.512 1.00 42.59 ? 217 ASN A C 1 ATOM 1264 O O . ASN A 1 217 ? -54.687 -8.099 -30.323 1.00 46.01 ? 217 ASN A O 1 ATOM 1265 C CB . ASN A 1 217 ? -54.211 -10.197 -32.264 1.00 45.42 ? 217 ASN A CB 1 ATOM 1266 C CG . ASN A 1 217 ? -54.708 -11.558 -32.734 1.00 47.48 ? 217 ASN A CG 1 ATOM 1267 O OD1 . ASN A 1 217 ? -55.909 -11.827 -32.728 1.00 45.02 ? 217 ASN A OD1 1 ATOM 1268 N ND2 . ASN A 1 217 ? -53.777 -12.426 -33.136 1.00 47.14 ? 217 ASN A ND2 1 ATOM 1269 N N . SER A 1 218 ? -54.941 -6.693 -32.058 1.00 41.66 ? 218 SER A N 1 ATOM 1270 C CA . SER A 1 218 ? -54.745 -5.492 -31.245 1.00 43.12 ? 218 SER A CA 1 ATOM 1271 C C . SER A 1 218 ? -55.853 -5.329 -30.218 1.00 49.79 ? 218 SER A C 1 ATOM 1272 O O . SER A 1 218 ? -56.976 -5.787 -30.426 1.00 58.74 ? 218 SER A O 1 ATOM 1273 C CB . SER A 1 218 ? -54.689 -4.240 -32.116 1.00 47.59 ? 218 SER A CB 1 ATOM 1274 O OG . SER A 1 218 ? -53.399 -4.058 -32.667 1.00 57.55 ? 218 SER A OG 1 ATOM 1275 N N . THR A 1 219 ? -55.533 -4.666 -29.112 1.00 46.50 ? 219 THR A N 1 ATOM 1276 C CA . THR A 1 219 ? -56.485 -4.509 -28.022 1.00 45.40 ? 219 THR A CA 1 ATOM 1277 C C . THR A 1 219 ? -56.722 -3.041 -27.686 1.00 43.98 ? 219 THR A C 1 ATOM 1278 O O . THR A 1 219 ? -55.773 -2.286 -27.469 1.00 41.34 ? 219 THR A O 1 ATOM 1279 C CB . THR A 1 219 ? -55.996 -5.241 -26.765 1.00 42.04 ? 219 THR A CB 1 ATOM 1280 O OG1 . THR A 1 219 ? -55.589 -6.569 -27.117 1.00 42.35 ? 219 THR A OG1 1 ATOM 1281 C CG2 . THR A 1 219 ? -57.099 -5.311 -25.728 1.00 44.53 ? 219 THR A CG2 1 ATOM 1282 N N . LEU A 1 220 ? -57.989 -2.635 -27.651 1.00 41.47 ? 220 LEU A N 1 ATOM 1283 C CA . LEU A 1 220 ? -58.334 -1.277 -27.244 1.00 37.56 ? 220 LEU A CA 1 ATOM 1284 C C . LEU A 1 220 ? -58.327 -1.209 -25.730 1.00 38.09 ? 220 LEU A C 1 ATOM 1285 O O . LEU A 1 220 ? -59.056 -1.945 -25.069 1.00 42.85 ? 220 LEU A O 1 ATOM 1286 C CB . LEU A 1 220 ? -59.709 -0.870 -27.773 1.00 35.79 ? 220 LEU A CB 1 ATOM 1287 C CG . LEU A 1 220 ? -60.320 0.378 -27.124 1.00 40.28 ? 220 LEU A CG 1 ATOM 1288 C CD1 . LEU A 1 220 ? -59.449 1.603 -27.346 1.00 39.46 ? 220 LEU A CD1 1 ATOM 1289 C CD2 . LEU A 1 220 ? -61.726 0.632 -27.641 1.00 58.02 ? 220 LEU A CD2 1 ATOM 1290 N N . ARG A 1 221 ? -57.499 -0.323 -25.185 1.00 40.27 ? 221 ARG A N 1 ATOM 1291 C CA . ARG A 1 221 ? -57.358 -0.189 -23.741 1.00 41.07 ? 221 ARG A CA 1 ATOM 1292 C C . ARG A 1 221 ? -57.243 1.273 -23.322 1.00 36.96 ? 221 ARG A C 1 ATOM 1293 O O . ARG A 1 221 ? -56.814 2.120 -24.105 1.00 33.41 ? 221 ARG A O 1 ATOM 1294 C CB . ARG A 1 221 ? -56.141 -0.981 -23.255 1.00 38.39 ? 221 ARG A CB 1 ATOM 1295 C CG . ARG A 1 221 ? -56.366 -2.486 -23.200 1.00 41.79 ? 221 ARG A CG 1 ATOM 1296 C CD . ARG A 1 221 ? -55.078 -3.258 -23.430 1.00 36.90 ? 221 ARG A CD 1 ATOM 1297 N NE . ARG A 1 221 ? -53.980 -2.743 -22.619 1.00 48.15 ? 221 ARG A NE 1 ATOM 1298 C CZ . ARG A 1 221 ? -52.767 -3.285 -22.576 1.00 56.00 ? 221 ARG A CZ 1 ATOM 1299 N NH1 . ARG A 1 221 ? -52.495 -4.368 -23.294 1.00 60.54 ? 221 ARG A NH1 1 ATOM 1300 N NH2 . ARG A 1 221 ? -51.826 -2.748 -21.810 1.00 51.07 ? 221 ARG A NH2 1 ATOM 1301 N N . ILE A 1 222 ? -57.636 1.563 -22.085 1.00 38.71 ? 222 ILE A N 1 ATOM 1302 C CA . ILE A 1 222 ? -57.529 2.914 -21.545 1.00 37.01 ? 222 ILE A CA 1 ATOM 1303 C C . ILE A 1 222 ? -56.256 3.047 -20.720 1.00 37.00 ? 222 ILE A C 1 ATOM 1304 O O . ILE A 1 222 ? -55.955 2.190 -19.889 1.00 38.29 ? 222 ILE A O 1 ATOM 1305 C CB . ILE A 1 222 ? -58.740 3.274 -20.668 1.00 33.71 ? 222 ILE A CB 1 ATOM 1306 C CG1 . ILE A 1 222 ? -60.041 3.077 -21.450 1.00 41.62 ? 222 ILE A CG1 1 ATOM 1307 C CG2 . ILE A 1 222 ? -58.630 4.704 -20.168 1.00 33.63 ? 222 ILE A CG2 1 ATOM 1308 C CD1 . ILE A 1 222 ? -61.282 3.535 -20.712 1.00 54.41 ? 222 ILE A CD1 1 ATOM 1309 N N . HIS A 1 223 ? -55.504 4.117 -20.960 1.00 39.10 ? 223 HIS A N 1 ATOM 1310 C CA . HIS A 1 223 ? -54.271 4.360 -20.223 1.00 41.69 ? 223 HIS A CA 1 ATOM 1311 C C . HIS A 1 223 ? -54.426 5.564 -19.309 1.00 43.20 ? 223 HIS A C 1 ATOM 1312 O O . HIS A 1 223 ? -54.985 6.588 -19.705 1.00 44.32 ? 223 HIS A O 1 ATOM 1313 C CB . HIS A 1 223 ? -53.098 4.583 -21.180 1.00 39.06 ? 223 HIS A CB 1 ATOM 1314 C CG . HIS A 1 223 ? -51.795 4.833 -20.490 1.00 38.13 ? 223 HIS A CG 1 ATOM 1315 N ND1 . HIS A 1 223 ? -51.268 6.097 -20.329 1.00 39.44 ? 223 HIS A ND1 1 ATOM 1316 C CD2 . HIS A 1 223 ? -50.913 3.983 -19.913 1.00 40.48 ? 223 HIS A CD2 1 ATOM 1317 C CE1 . HIS A 1 223 ? -50.119 6.014 -19.684 1.00 40.91 ? 223 HIS A CE1 1 ATOM 1318 N NE2 . HIS A 1 223 ? -49.880 4.741 -19.420 1.00 43.78 ? 223 HIS A NE2 1 ATOM 1319 N N . VAL A 1 224 ? -53.937 5.431 -18.081 1.00 36.73 ? 224 VAL A N 1 ATOM 1320 C CA . VAL A 1 224 ? -53.949 6.530 -17.130 1.00 34.07 ? 224 VAL A CA 1 ATOM 1321 C C . VAL A 1 224 ? -52.521 6.998 -16.889 1.00 38.29 ? 224 VAL A C 1 ATOM 1322 O O . VAL A 1 224 ? -51.705 6.254 -16.344 1.00 42.40 ? 224 VAL A O 1 ATOM 1323 C CB . VAL A 1 224 ? -54.600 6.117 -15.793 1.00 37.20 ? 224 VAL A CB 1 ATOM 1324 C CG1 . VAL A 1 224 ? -54.339 7.161 -14.722 1.00 39.49 ? 224 VAL A CG1 1 ATOM 1325 C CG2 . VAL A 1 224 ? -56.095 5.900 -15.975 1.00 43.79 ? 224 VAL A CG2 1 ATOM 1326 N N . PRO A 1 225 ? -52.208 8.229 -17.316 1.00 37.23 ? 225 PRO A N 1 ATOM 1327 C CA . PRO A 1 225 ? -50.876 8.800 -17.094 1.00 38.29 ? 225 PRO A CA 1 ATOM 1328 C C . PRO A 1 225 ? -50.585 9.031 -15.614 1.00 42.13 ? 225 PRO A C 1 ATOM 1329 O O . PRO A 1 225 ? -51.503 9.016 -14.794 1.00 42.60 ? 225 PRO A O 1 ATOM 1330 C CB . PRO A 1 225 ? -50.931 10.133 -17.847 1.00 35.41 ? 225 PRO A CB 1 ATOM 1331 C CG . PRO A 1 225 ? -52.370 10.443 -17.980 1.00 32.81 ? 225 PRO A CG 1 ATOM 1332 C CD . PRO A 1 225 ? -53.072 9.130 -18.096 1.00 34.85 ? 225 PRO A CD 1 ATOM 1333 N N . LEU A 1 226 ? -49.314 9.248 -15.294 1.00 49.26 ? 226 LEU A N 1 ATOM 1334 C CA . LEU A 1 226 ? -48.842 9.325 -13.912 1.00 47.69 ? 226 LEU A CA 1 ATOM 1335 C C . LEU A 1 226 ? -49.625 10.301 -13.032 1.00 45.42 ? 226 LEU A C 1 ATOM 1336 O O . LEU A 1 226 ? -49.833 11.456 -13.398 1.00 44.36 ? 226 LEU A O 1 ATOM 1337 C CB . LEU A 1 226 ? -47.358 9.703 -13.898 1.00 43.22 ? 226 LEU A CB 1 ATOM 1338 C CG . LEU A 1 226 ? -46.660 9.836 -12.545 1.00 40.80 ? 226 LEU A CG 1 ATOM 1339 C CD1 . LEU A 1 226 ? -46.583 8.488 -11.857 1.00 46.75 ? 226 LEU A CD1 1 ATOM 1340 C CD2 . LEU A 1 226 ? -45.272 10.424 -12.722 1.00 42.24 ? 226 LEU A CD2 1 ATOM 1341 N N . PHE A 1 227 ? -50.067 9.804 -11.879 1.00 47.69 ? 227 PHE A N 1 ATOM 1342 C CA . PHE A 1 227 ? -50.684 10.614 -10.821 1.00 50.63 ? 227 PHE A CA 1 ATOM 1343 C C . PHE A 1 227 ? -51.896 11.434 -11.264 1.00 44.02 ? 227 PHE A C 1 ATOM 1344 O O . PHE A 1 227 ? -52.218 12.450 -10.648 1.00 39.61 ? 227 PHE A O 1 ATOM 1345 C CB . PHE A 1 227 ? -49.640 11.527 -10.159 1.00 55.27 ? 227 PHE A CB 1 ATOM 1346 C CG . PHE A 1 227 ? -48.548 10.784 -9.435 1.00 46.37 ? 227 PHE A CG 1 ATOM 1347 C CD1 . PHE A 1 227 ? -48.699 9.446 -9.105 1.00 45.38 ? 227 PHE A CD1 1 ATOM 1348 C CD2 . PHE A 1 227 ? -47.373 11.425 -9.079 1.00 38.18 ? 227 PHE A CD2 1 ATOM 1349 C CE1 . PHE A 1 227 ? -47.697 8.762 -8.440 1.00 41.00 ? 227 PHE A CE1 1 ATOM 1350 C CE2 . PHE A 1 227 ? -46.369 10.747 -8.411 1.00 37.49 ? 227 PHE A CE2 1 ATOM 1351 C CZ . PHE A 1 227 ? -46.532 9.414 -8.092 1.00 36.97 ? 227 PHE A CZ 1 ATOM 1352 N N . GLY A 1 228 ? -52.576 10.983 -12.313 1.00 41.57 ? 228 GLY A N 1 ATOM 1353 C CA . GLY A 1 228 ? -53.684 11.736 -12.870 1.00 41.89 ? 228 GLY A CA 1 ATOM 1354 C C . GLY A 1 228 ? -53.252 13.124 -13.305 1.00 42.90 ? 228 GLY A C 1 ATOM 1355 O O . GLY A 1 228 ? -54.030 14.076 -13.250 1.00 39.47 ? 228 GLY A O 1 ATOM 1356 N N . SER A 1 229 ? -51.997 13.236 -13.729 1.00 45.17 ? 229 SER A N 1 ATOM 1357 C CA . SER A 1 229 ? -51.434 14.509 -14.158 1.00 44.34 ? 229 SER A CA 1 ATOM 1358 C C . SER A 1 229 ? -52.090 14.978 -15.446 1.00 47.09 ? 229 SER A C 1 ATOM 1359 O O . SER A 1 229 ? -52.305 16.172 -15.648 1.00 48.41 ? 229 SER A O 1 ATOM 1360 C CB . SER A 1 229 ? -49.932 14.371 -14.376 1.00 40.72 ? 229 SER A CB 1 ATOM 1361 O OG . SER A 1 229 ? -49.320 13.731 -13.274 1.00 43.62 ? 229 SER A OG 1 ATOM 1362 N N . VAL A 1 230 ? -52.384 14.024 -16.323 1.00 44.54 ? 230 VAL A N 1 ATOM 1363 C CA . VAL A 1 230 ? -53.099 14.293 -17.563 1.00 44.75 ? 230 VAL A CA 1 ATOM 1364 C C . VAL A 1 230 ? -54.349 13.415 -17.567 1.00 44.81 ? 230 VAL A C 1 ATOM 1365 O O . VAL A 1 230 ? -54.403 12.414 -16.856 1.00 45.44 ? 230 VAL A O 1 ATOM 1366 C CB . VAL A 1 230 ? -52.221 13.984 -18.795 1.00 41.53 ? 230 VAL A CB 1 ATOM 1367 C CG1 . VAL A 1 230 ? -52.834 14.566 -20.057 1.00 50.15 ? 230 VAL A CG1 1 ATOM 1368 C CG2 . VAL A 1 230 ? -50.823 14.537 -18.603 1.00 39.82 ? 230 VAL A CG2 1 ATOM 1369 N N . TRP A 1 231 ? -55.362 13.795 -18.340 1.00 42.50 ? 231 TRP A N 1 ATOM 1370 C CA . TRP A 1 231 ? -56.590 13.009 -18.426 1.00 37.33 ? 231 TRP A CA 1 ATOM 1371 C C . TRP A 1 231 ? -56.331 11.712 -19.196 1.00 35.98 ? 231 TRP A C 1 ATOM 1372 O O . TRP A 1 231 ? -55.378 11.644 -19.969 1.00 38.68 ? 231 TRP A O 1 ATOM 1373 C CB . TRP A 1 231 ? -57.700 13.838 -19.079 1.00 43.91 ? 231 TRP A CB 1 ATOM 1374 C CG . TRP A 1 231 ? -58.000 15.113 -18.347 1.00 42.41 ? 231 TRP A CG 1 ATOM 1375 C CD1 . TRP A 1 231 ? -58.025 16.373 -18.870 1.00 46.24 ? 231 TRP A CD1 1 ATOM 1376 C CD2 . TRP A 1 231 ? -58.302 15.251 -16.954 1.00 44.75 ? 231 TRP A CD2 1 ATOM 1377 N NE1 . TRP A 1 231 ? -58.332 17.286 -17.891 1.00 44.99 ? 231 TRP A NE1 1 ATOM 1378 C CE2 . TRP A 1 231 ? -58.505 16.622 -16.705 1.00 48.73 ? 231 TRP A CE2 1 ATOM 1379 C CE3 . TRP A 1 231 ? -58.425 14.348 -15.894 1.00 46.34 ? 231 TRP A CE3 1 ATOM 1380 C CZ2 . TRP A 1 231 ? -58.824 17.110 -15.439 1.00 51.75 ? 231 TRP A CZ2 1 ATOM 1381 C CZ3 . TRP A 1 231 ? -58.737 14.833 -14.643 1.00 47.16 ? 231 TRP A CZ3 1 ATOM 1382 C CH2 . TRP A 1 231 ? -58.934 16.199 -14.423 1.00 49.18 ? 231 TRP A CH2 1 ATOM 1383 N N . PRO A 1 232 ? -57.169 10.677 -18.984 1.00 34.56 ? 232 PRO A N 1 ATOM 1384 C CA . PRO A 1 232 ? -56.912 9.353 -19.571 1.00 33.09 ? 232 PRO A CA 1 ATOM 1385 C C . PRO A 1 232 ? -56.721 9.360 -21.086 1.00 35.35 ? 232 PRO A C 1 ATOM 1386 O O . PRO A 1 232 ? -57.241 10.237 -21.774 1.00 39.89 ? 232 PRO A O 1 ATOM 1387 C CB . PRO A 1 232 ? -58.176 8.567 -19.217 1.00 35.05 ? 232 PRO A CB 1 ATOM 1388 C CG . PRO A 1 232 ? -58.654 9.192 -17.963 1.00 40.37 ? 232 PRO A CG 1 ATOM 1389 C CD . PRO A 1 232 ? -58.356 10.659 -18.107 1.00 36.99 ? 232 PRO A CD 1 ATOM 1390 N N . ILE A 1 233 ? -55.969 8.386 -21.588 1.00 35.16 ? 233 ILE A N 1 ATOM 1391 C CA . ILE A 1 233 ? -55.702 8.267 -23.018 1.00 40.81 ? 233 ILE A CA 1 ATOM 1392 C C . ILE A 1 233 ? -56.123 6.885 -23.515 1.00 44.20 ? 233 ILE A C 1 ATOM 1393 O O . ILE A 1 233 ? -55.810 5.876 -22.884 1.00 43.55 ? 233 ILE A O 1 ATOM 1394 C CB . ILE A 1 233 ? -54.208 8.487 -23.326 1.00 38.24 ? 233 ILE A CB 1 ATOM 1395 C CG1 . ILE A 1 233 ? -53.784 9.905 -22.942 1.00 36.56 ? 233 ILE A CG1 1 ATOM 1396 C CG2 . ILE A 1 233 ? -53.915 8.239 -24.795 1.00 38.44 ? 233 ILE A CG2 1 ATOM 1397 C CD1 . ILE A 1 233 ? -52.320 10.185 -23.185 1.00 28.84 ? 233 ILE A CD1 1 ATOM 1398 N N . ARG A 1 234 ? -56.837 6.841 -24.638 1.00 39.61 ? 234 ARG A N 1 ATOM 1399 C CA . ARG A 1 234 ? -57.263 5.572 -25.225 1.00 33.18 ? 234 ARG A CA 1 ATOM 1400 C C . ARG A 1 234 ? -56.417 5.204 -26.436 1.00 31.97 ? 234 ARG A C 1 ATOM 1401 O O . ARG A 1 234 ? -56.339 5.961 -27.403 1.00 33.08 ? 234 ARG A O 1 ATOM 1402 C CB . ARG A 1 234 ? -58.740 5.623 -25.613 1.00 35.45 ? 234 ARG A CB 1 ATOM 1403 C CG . ARG A 1 234 ? -59.679 5.693 -24.424 1.00 45.89 ? 234 ARG A CG 1 ATOM 1404 C CD . ARG A 1 234 ? -61.108 5.982 -24.850 1.00 52.34 ? 234 ARG A CD 1 ATOM 1405 N NE . ARG A 1 234 ? -62.030 5.894 -23.723 1.00 57.48 ? 234 ARG A NE 1 ATOM 1406 C CZ . ARG A 1 234 ? -63.043 5.035 -23.654 1.00 70.63 ? 234 ARG A CZ 1 ATOM 1407 N NH1 . ARG A 1 234 ? -63.273 4.197 -24.657 1.00 70.53 ? 234 ARG A NH1 1 ATOM 1408 N NH2 . ARG A 1 234 ? -63.832 5.021 -22.588 1.00 73.87 ? 234 ARG A NH2 1 ATOM 1409 N N . TYR A 1 235 ? -55.789 4.035 -26.376 1.00 31.93 ? 235 TYR A N 1 ATOM 1410 C CA . TYR A 1 235 ? -54.921 3.573 -27.452 1.00 31.93 ? 235 TYR A CA 1 ATOM 1411 C C . TYR A 1 235 ? -55.242 2.134 -27.821 1.00 31.63 ? 235 TYR A C 1 ATOM 1412 O O . TYR A 1 235 ? -55.909 1.427 -27.068 1.00 34.57 ? 235 TYR A O 1 ATOM 1413 C CB . TYR A 1 235 ? -53.447 3.684 -27.040 1.00 37.79 ? 235 TYR A CB 1 ATOM 1414 C CG . TYR A 1 235 ? -53.014 2.713 -25.955 1.00 35.51 ? 235 TYR A CG 1 ATOM 1415 C CD1 . TYR A 1 235 ? -53.256 2.983 -24.616 1.00 31.24 ? 235 TYR A CD1 1 ATOM 1416 C CD2 . TYR A 1 235 ? -52.343 1.536 -26.271 1.00 34.00 ? 235 TYR A CD2 1 ATOM 1417 C CE1 . TYR A 1 235 ? -52.857 2.104 -23.625 1.00 32.82 ? 235 TYR A CE1 1 ATOM 1418 C CE2 . TYR A 1 235 ? -51.940 0.653 -25.283 1.00 33.11 ? 235 TYR A CE2 1 ATOM 1419 C CZ . TYR A 1 235 ? -52.201 0.943 -23.962 1.00 32.54 ? 235 TYR A CZ 1 ATOM 1420 O OH . TYR A 1 235 ? -51.805 0.073 -22.971 1.00 33.40 ? 235 TYR A OH 1 ATOM 1421 N N . TRP A 1 236 ? -54.761 1.703 -28.981 1.00 30.20 ? 236 TRP A N 1 ATOM 1422 C CA . TRP A 1 236 ? -54.896 0.312 -29.388 1.00 36.21 ? 236 TRP A CA 1 ATOM 1423 C C . TRP A 1 236 ? -53.587 -0.424 -29.132 1.00 42.04 ? 236 TRP A C 1 ATOM 1424 O O . TRP A 1 236 ? -52.584 -0.179 -29.800 1.00 46.16 ? 236 TRP A O 1 ATOM 1425 C CB . TRP A 1 236 ? -55.297 0.227 -30.859 1.00 40.91 ? 236 TRP A CB 1 ATOM 1426 C CG . TRP A 1 236 ? -56.705 0.668 -31.088 1.00 43.45 ? 236 TRP A CG 1 ATOM 1427 C CD1 . TRP A 1 236 ? -57.147 1.947 -31.270 1.00 46.34 ? 236 TRP A CD1 1 ATOM 1428 C CD2 . TRP A 1 236 ? -57.862 -0.168 -31.140 1.00 39.14 ? 236 TRP A CD2 1 ATOM 1429 N NE1 . TRP A 1 236 ? -58.509 1.957 -31.438 1.00 40.13 ? 236 TRP A NE1 1 ATOM 1430 C CE2 . TRP A 1 236 ? -58.973 0.668 -31.363 1.00 36.33 ? 236 TRP A CE2 1 ATOM 1431 C CE3 . TRP A 1 236 ? -58.069 -1.545 -31.024 1.00 40.79 ? 236 TRP A CE3 1 ATOM 1432 C CZ2 . TRP A 1 236 ? -60.270 0.172 -31.471 1.00 45.48 ? 236 TRP A CZ2 1 ATOM 1433 C CZ3 . TRP A 1 236 ? -59.353 -2.034 -31.132 1.00 39.89 ? 236 TRP A CZ3 1 ATOM 1434 C CH2 . TRP A 1 236 ? -60.437 -1.181 -31.353 1.00 47.36 ? 236 TRP A CH2 1 ATOM 1435 N N . ALA A 1 237 ? -53.609 -1.330 -28.162 1.00 40.54 ? 237 ALA A N 1 ATOM 1436 C CA . ALA A 1 237 ? -52.389 -1.954 -27.660 1.00 41.33 ? 237 ALA A CA 1 ATOM 1437 C C . ALA A 1 237 ? -51.658 -2.820 -28.685 1.00 46.06 ? 237 ALA A C 1 ATOM 1438 O O . ALA A 1 237 ? -52.274 -3.418 -29.567 1.00 52.11 ? 237 ALA A O 1 ATOM 1439 C CB . ALA A 1 237 ? -52.690 -2.760 -26.407 1.00 45.03 ? 237 ALA A CB 1 ATOM 1440 N N . THR A 1 238 ? -50.336 -2.866 -28.550 1.00 41.14 ? 238 THR A N 1 ATOM 1441 C CA . THR A 1 238 ? -49.477 -3.756 -29.326 1.00 37.05 ? 238 THR A CA 1 ATOM 1442 C C . THR A 1 238 ? -48.668 -4.630 -28.371 1.00 39.89 ? 238 THR A C 1 ATOM 1443 O O . THR A 1 238 ? -48.738 -5.855 -28.425 1.00 39.35 ? 238 THR A O 1 ATOM 1444 C CB . THR A 1 238 ? -48.543 -3.000 -30.287 1.00 32.49 ? 238 THR A CB 1 ATOM 1445 O OG1 . THR A 1 238 ? -47.876 -1.948 -29.585 1.00 38.90 ? 238 THR A OG1 1 ATOM 1446 C CG2 . THR A 1 238 ? -49.336 -2.406 -31.434 1.00 31.46 ? 238 THR A CG2 1 ATOM 1447 N N . GLY A 1 239 ? -47.884 -3.998 -27.505 1.00 39.69 ? 239 GLY A N 1 ATOM 1448 C CA . GLY A 1 239 ? -47.116 -4.748 -26.528 1.00 38.01 ? 239 GLY A CA 1 ATOM 1449 C C . GLY A 1 239 ? -46.963 -4.065 -25.182 1.00 38.48 ? 239 GLY A C 1 ATOM 1450 O O . GLY A 1 239 ? -47.255 -2.878 -25.030 1.00 34.79 ? 239 GLY A O 1 ATOM 1451 N N . SER A 1 240 ? -46.515 -4.837 -24.196 1.00 37.10 ? 240 SER A N 1 ATOM 1452 C CA . SER A 1 240 ? -46.316 -4.334 -22.842 1.00 37.80 ? 240 SER A CA 1 ATOM 1453 C C . SER A 1 240 ? -45.014 -4.881 -22.268 1.00 40.33 ? 240 SER A C 1 ATOM 1454 O O . SER A 1 240 ? -44.752 -6.079 -22.354 1.00 46.27 ? 240 SER A O 1 ATOM 1455 C CB . SER A 1 240 ? -47.490 -4.736 -21.948 1.00 45.26 ? 240 SER A CB 1 ATOM 1456 O OG . SER A 1 240 ? -47.620 -6.146 -21.877 1.00 51.43 ? 240 SER A OG 1 ATOM 1457 N N . VAL A 1 241 ? -44.196 -4.004 -21.691 1.00 35.20 ? 241 VAL A N 1 ATOM 1458 C CA . VAL A 1 241 ? -42.911 -4.416 -21.129 1.00 32.31 ? 241 VAL A CA 1 ATOM 1459 C C . VAL A 1 241 ? -42.824 -4.078 -19.641 1.00 35.05 ? 241 VAL A C 1 ATOM 1460 O O . VAL A 1 241 ? -43.186 -2.977 -19.228 1.00 36.91 ? 241 VAL A O 1 ATOM 1461 C CB . VAL A 1 241 ? -41.731 -3.753 -21.867 1.00 28.58 ? 241 VAL A CB 1 ATOM 1462 C CG1 . VAL A 1 241 ? -40.422 -4.392 -21.453 1.00 27.68 ? 241 VAL A CG1 1 ATOM 1463 C CG2 . VAL A 1 241 ? -41.913 -3.869 -23.366 1.00 33.22 ? 241 VAL A CG2 1 ATOM 1464 N N . LEU A 1 242 ? -42.347 -5.027 -18.840 1.00 33.80 ? 242 LEU A N 1 ATOM 1465 C CA . LEU A 1 242 ? -42.185 -4.808 -17.405 1.00 29.13 ? 242 LEU A CA 1 ATOM 1466 C C . LEU A 1 242 ? -40.804 -5.235 -16.928 1.00 35.17 ? 242 LEU A C 1 ATOM 1467 O O . LEU A 1 242 ? -40.455 -6.412 -17.000 1.00 37.73 ? 242 LEU A O 1 ATOM 1468 C CB . LEU A 1 242 ? -43.244 -5.581 -16.618 1.00 29.66 ? 242 LEU A CB 1 ATOM 1469 C CG . LEU A 1 242 ? -43.113 -5.508 -15.095 1.00 29.41 ? 242 LEU A CG 1 ATOM 1470 C CD1 . LEU A 1 242 ? -43.623 -4.172 -14.585 1.00 32.57 ? 242 LEU A CD1 1 ATOM 1471 C CD2 . LEU A 1 242 ? -43.838 -6.662 -14.416 1.00 31.65 ? 242 LEU A CD2 1 ATOM 1472 N N . LEU A 1 243 ? -40.022 -4.278 -16.437 1.00 36.11 ? 243 LEU A N 1 ATOM 1473 C CA . LEU A 1 243 ? -38.734 -4.586 -15.826 1.00 36.56 ? 243 LEU A CA 1 ATOM 1474 C C . LEU A 1 243 ? -38.775 -4.171 -14.358 1.00 44.97 ? 243 LEU A C 1 ATOM 1475 O O . LEU A 1 243 ? -39.041 -3.011 -14.040 1.00 45.37 ? 243 LEU A O 1 ATOM 1476 C CB . LEU A 1 243 ? -37.601 -3.864 -16.555 1.00 29.76 ? 243 LEU A CB 1 ATOM 1477 C CG . LEU A 1 243 ? -37.578 -3.980 -18.081 1.00 27.88 ? 243 LEU A CG 1 ATOM 1478 C CD1 . LEU A 1 243 ? -36.493 -3.092 -18.662 1.00 30.74 ? 243 LEU A CD1 1 ATOM 1479 C CD2 . LEU A 1 243 ? -37.376 -5.420 -18.515 1.00 31.66 ? 243 LEU A CD2 1 ATOM 1480 N N . THR A 1 244 ? -38.526 -5.121 -13.463 1.00 48.86 ? 244 THR A N 1 ATOM 1481 C CA . THR A 1 244 ? -38.642 -4.855 -12.032 1.00 48.43 ? 244 THR A CA 1 ATOM 1482 C C . THR A 1 244 ? -37.393 -5.235 -11.236 1.00 52.36 ? 244 THR A C 1 ATOM 1483 O O . THR A 1 244 ? -36.609 -6.091 -11.648 1.00 51.41 ? 244 THR A O 1 ATOM 1484 C CB . THR A 1 244 ? -39.890 -5.535 -11.427 1.00 45.17 ? 244 THR A CB 1 ATOM 1485 O OG1 . THR A 1 244 ? -39.977 -6.887 -11.892 1.00 48.05 ? 244 THR A OG1 1 ATOM 1486 C CG2 . THR A 1 244 ? -41.146 -4.791 -11.844 1.00 40.70 ? 244 THR A CG2 1 ATOM 1487 N N . SER A 1 245 ? -37.219 -4.571 -10.098 1.00 54.39 ? 245 SER A N 1 ATOM 1488 C CA . SER A 1 245 ? -36.095 -4.803 -9.199 1.00 57.20 ? 245 SER A CA 1 ATOM 1489 C C . SER A 1 245 ? -36.438 -4.232 -7.831 1.00 60.34 ? 245 SER A C 1 ATOM 1490 O O . SER A 1 245 ? -37.582 -3.857 -7.578 1.00 62.51 ? 245 SER A O 1 ATOM 1491 C CB . SER A 1 245 ? -34.824 -4.140 -9.732 1.00 50.27 ? 245 SER A CB 1 ATOM 1492 O OG . SER A 1 245 ? -34.962 -2.730 -9.776 1.00 47.72 ? 245 SER A OG 1 ATOM 1493 N N . ASP A 1 246 ? -35.449 -4.175 -6.949 1.00 59.30 ? 246 ASP A N 1 ATOM 1494 C CA . ASP A 1 246 ? -35.614 -3.496 -5.672 1.00 59.48 ? 246 ASP A CA 1 ATOM 1495 C C . ASP A 1 246 ? -35.585 -1.994 -5.913 1.00 60.13 ? 246 ASP A C 1 ATOM 1496 O O . ASP A 1 246 ? -36.560 -1.287 -5.660 1.00 53.93 ? 246 ASP A O 1 ATOM 1497 C CB . ASP A 1 246 ? -34.486 -3.869 -4.713 1.00 68.57 ? 246 ASP A CB 1 ATOM 1498 C CG . ASP A 1 246 ? -34.273 -5.360 -4.621 1.00 72.69 ? 246 ASP A CG 1 ATOM 1499 O OD1 . ASP A 1 246 ? -35.253 -6.109 -4.826 1.00 71.90 ? 246 ASP A OD1 1 ATOM 1500 O OD2 . ASP A 1 246 ? -33.130 -5.786 -4.349 1.00 69.70 ? 246 ASP A OD2 1 ATOM 1501 N N . SER A 1 247 ? -34.446 -1.522 -6.408 1.00 65.70 ? 247 SER A N 1 ATOM 1502 C CA . SER A 1 247 ? -34.188 -0.099 -6.588 1.00 66.40 ? 247 SER A CA 1 ATOM 1503 C C . SER A 1 247 ? -35.084 0.583 -7.620 1.00 59.29 ? 247 SER A C 1 ATOM 1504 O O . SER A 1 247 ? -35.214 1.805 -7.611 1.00 61.32 ? 247 SER A O 1 ATOM 1505 C CB . SER A 1 247 ? -32.719 0.133 -6.952 1.00 60.95 ? 247 SER A CB 1 ATOM 1506 O OG . SER A 1 247 ? -31.853 -0.319 -5.925 1.00 61.12 ? 247 SER A OG 1 ATOM 1507 N N . GLY A 1 248 ? -35.695 -0.188 -8.514 1.00 52.73 ? 248 GLY A N 1 ATOM 1508 C CA . GLY A 1 248 ? -36.564 0.415 -9.507 1.00 50.85 ? 248 GLY A CA 1 ATOM 1509 C C . GLY A 1 248 ? -37.424 -0.524 -10.326 1.00 50.25 ? 248 GLY A C 1 ATOM 1510 O O . GLY A 1 248 ? -37.098 -1.697 -10.510 1.00 53.35 ? 248 GLY A O 1 ATOM 1511 N N . ARG A 1 249 ? -38.532 0.014 -10.826 1.00 48.21 ? 249 ARG A N 1 ATOM 1512 C CA . ARG A 1 249 ? -39.409 -0.707 -11.737 1.00 42.37 ? 249 ARG A CA 1 ATOM 1513 C C . ARG A 1 249 ? -39.743 0.211 -12.903 1.00 43.38 ? 249 ARG A C 1 ATOM 1514 O O . ARG A 1 249 ? -39.877 1.424 -12.729 1.00 46.99 ? 249 ARG A O 1 ATOM 1515 C CB . ARG A 1 249 ? -40.689 -1.166 -11.024 1.00 41.33 ? 249 ARG A CB 1 ATOM 1516 C CG . ARG A 1 249 ? -41.978 -0.487 -11.490 1.00 36.81 ? 249 ARG A CG 1 ATOM 1517 C CD . ARG A 1 249 ? -43.189 -0.959 -10.694 1.00 39.17 ? 249 ARG A CD 1 ATOM 1518 N NE . ARG A 1 249 ? -43.382 -2.405 -10.774 1.00 39.42 ? 249 ARG A NE 1 ATOM 1519 C CZ . ARG A 1 249 ? -44.511 -2.993 -11.153 1.00 35.98 ? 249 ARG A CZ 1 ATOM 1520 N NH1 . ARG A 1 249 ? -45.561 -2.259 -11.486 1.00 43.00 ? 249 ARG A NH1 1 ATOM 1521 N NH2 . ARG A 1 249 ? -44.592 -4.316 -11.195 1.00 30.54 ? 249 ARG A NH2 1 ATOM 1522 N N . VAL A 1 250 ? -39.846 -0.360 -14.097 1.00 39.86 ? 250 VAL A N 1 ATOM 1523 C CA . VAL A 1 250 ? -40.259 0.412 -15.260 1.00 31.36 ? 250 VAL A CA 1 ATOM 1524 C C . VAL A 1 250 ? -41.377 -0.294 -16.029 1.00 31.12 ? 250 VAL A C 1 ATOM 1525 O O . VAL A 1 250 ? -41.264 -1.470 -16.375 1.00 30.81 ? 250 VAL A O 1 ATOM 1526 C CB . VAL A 1 250 ? -39.060 0.778 -16.182 1.00 26.31 ? 250 VAL A CB 1 ATOM 1527 C CG1 . VAL A 1 250 ? -38.332 -0.461 -16.660 1.00 21.40 ? 250 VAL A CG1 1 ATOM 1528 C CG2 . VAL A 1 250 ? -39.525 1.617 -17.357 1.00 32.86 ? 250 VAL A CG2 1 ATOM 1529 N N . GLU A 1 251 ? -42.472 0.425 -16.255 1.00 28.98 ? 251 GLU A N 1 ATOM 1530 C CA . GLU A 1 251 ? -43.603 -0.113 -17.001 1.00 26.17 ? 251 GLU A CA 1 ATOM 1531 C C . GLU A 1 251 ? -43.665 0.537 -18.374 1.00 31.24 ? 251 GLU A C 1 ATOM 1532 O O . GLU A 1 251 ? -43.658 1.761 -18.489 1.00 31.40 ? 251 GLU A O 1 ATOM 1533 C CB . GLU A 1 251 ? -44.918 0.127 -16.256 1.00 30.41 ? 251 GLU A CB 1 ATOM 1534 C CG . GLU A 1 251 ? -45.048 -0.627 -14.942 1.00 37.02 ? 251 GLU A CG 1 ATOM 1535 C CD . GLU A 1 251 ? -46.429 -0.489 -14.322 1.00 51.09 ? 251 GLU A CD 1 ATOM 1536 O OE1 . GLU A 1 251 ? -47.363 -0.054 -15.029 1.00 61.04 ? 251 GLU A OE1 1 ATOM 1537 O OE2 . GLU A 1 251 ? -46.580 -0.818 -13.126 1.00 52.48 ? 251 GLU A OE2 1 ATOM 1538 N N . VAL A 1 252 ? -43.723 -0.287 -19.414 1.00 33.74 ? 252 VAL A N 1 ATOM 1539 C CA . VAL A 1 252 ? -43.781 0.217 -20.777 1.00 30.95 ? 252 VAL A CA 1 ATOM 1540 C C . VAL A 1 252 ? -45.039 -0.280 -21.483 1.00 29.39 ? 252 VAL A C 1 ATOM 1541 O O . VAL A 1 252 ? -45.248 -1.484 -21.617 1.00 29.04 ? 252 VAL A O 1 ATOM 1542 C CB . VAL A 1 252 ? -42.533 -0.196 -21.584 1.00 30.47 ? 252 VAL A CB 1 ATOM 1543 C CG1 . VAL A 1 252 ? -42.594 0.387 -22.977 1.00 31.55 ? 252 VAL A CG1 1 ATOM 1544 C CG2 . VAL A 1 252 ? -41.267 0.261 -20.882 1.00 23.33 ? 252 VAL A CG2 1 ATOM 1545 N N . ASN A 1 253 ? -45.881 0.656 -21.913 1.00 31.44 ? 253 ASN A N 1 ATOM 1546 C CA . ASN A 1 253 ? -47.060 0.324 -22.709 1.00 35.04 ? 253 ASN A CA 1 ATOM 1547 C C . ASN A 1 253 ? -46.961 0.896 -24.122 1.00 31.55 ? 253 ASN A C 1 ATOM 1548 O O . ASN A 1 253 ? -46.863 2.110 -24.310 1.00 30.25 ? 253 ASN A O 1 ATOM 1549 C CB . ASN A 1 253 ? -48.347 0.807 -22.029 1.00 42.80 ? 253 ASN A CB 1 ATOM 1550 C CG . ASN A 1 253 ? -48.699 -0.001 -20.791 1.00 43.40 ? 253 ASN A CG 1 ATOM 1551 O OD1 . ASN A 1 253 ? -47.819 -0.448 -20.055 1.00 44.43 ? 253 ASN A OD1 1 ATOM 1552 N ND2 . ASN A 1 253 ? -49.994 -0.195 -20.560 1.00 39.50 ? 253 ASN A ND2 1 ATOM 1553 N N . ILE A 1 254 ? -46.987 0.012 -25.112 1.00 29.14 ? 254 ILE A N 1 ATOM 1554 C CA . ILE A 1 254 ? -46.811 0.412 -26.501 1.00 27.50 ? 254 ILE A CA 1 ATOM 1555 C C . ILE A 1 254 ? -48.018 0.000 -27.334 1.00 36.98 ? 254 ILE A C 1 ATOM 1556 O O . ILE A 1 254 ? -48.519 -1.117 -27.208 1.00 43.51 ? 254 ILE A O 1 ATOM 1557 C CB . ILE A 1 254 ? -45.502 -0.170 -27.074 1.00 24.95 ? 254 ILE A CB 1 ATOM 1558 C CG1 . ILE A 1 254 ? -44.317 0.622 -26.528 1.00 33.93 ? 254 ILE A CG1 1 ATOM 1559 C CG2 . ILE A 1 254 ? -45.486 -0.106 -28.585 1.00 24.28 ? 254 ILE A CG2 1 ATOM 1560 C CD1 . ILE A 1 254 ? -43.048 -0.162 -26.416 1.00 32.02 ? 254 ILE A CD1 1 ATOM 1561 N N . GLY A 1 255 ? -48.473 0.911 -28.188 1.00 37.48 ? 255 GLY A N 1 ATOM 1562 C CA . GLY A 1 255 ? -49.678 0.715 -28.972 1.00 33.03 ? 255 GLY A CA 1 ATOM 1563 C C . GLY A 1 255 ? -49.571 1.473 -30.278 1.00 30.47 ? 255 GLY A C 1 ATOM 1564 O O . GLY A 1 255 ? -48.520 2.036 -30.585 1.00 25.01 ? 255 GLY A O 1 ATOM 1565 N N . VAL A 1 256 ? -50.648 1.486 -31.056 1.00 34.04 ? 256 VAL A N 1 ATOM 1566 C CA . VAL A 1 256 ? -50.613 2.124 -32.364 1.00 31.04 ? 256 VAL A CA 1 ATOM 1567 C C . VAL A 1 256 ? -50.438 3.624 -32.183 1.00 28.60 ? 256 VAL A C 1 ATOM 1568 O O . VAL A 1 256 ? -51.255 4.281 -31.540 1.00 27.20 ? 256 VAL A O 1 ATOM 1569 C CB . VAL A 1 256 ? -51.913 1.856 -33.140 1.00 31.52 ? 256 VAL A CB 1 ATOM 1570 C CG1 . VAL A 1 256 ? -51.954 2.670 -34.422 1.00 36.41 ? 256 VAL A CG1 1 ATOM 1571 C CG2 . VAL A 1 256 ? -52.052 0.372 -33.435 1.00 33.88 ? 256 VAL A CG2 1 ATOM 1572 N N . GLY A 1 257 ? -49.366 4.154 -32.763 1.00 28.97 ? 257 GLY A N 1 ATOM 1573 C CA . GLY A 1 257 ? -49.003 5.549 -32.594 1.00 25.84 ? 257 GLY A CA 1 ATOM 1574 C C . GLY A 1 257 ? -48.957 5.979 -31.140 1.00 23.95 ? 257 GLY A C 1 ATOM 1575 O O . GLY A 1 257 ? -49.226 7.135 -30.831 1.00 23.67 ? 257 GLY A O 1 ATOM 1576 N N . PHE A 1 258 ? -48.611 5.056 -30.246 1.00 24.67 ? 258 PHE A N 1 ATOM 1577 C CA . PHE A 1 258 ? -48.618 5.357 -28.820 1.00 25.69 ? 258 PHE A CA 1 ATOM 1578 C C . PHE A 1 258 ? -47.553 4.620 -28.014 1.00 27.39 ? 258 PHE A C 1 ATOM 1579 O O . PHE A 1 258 ? -47.293 3.437 -28.240 1.00 27.49 ? 258 PHE A O 1 ATOM 1580 C CB . PHE A 1 258 ? -49.997 5.053 -28.244 1.00 30.38 ? 258 PHE A CB 1 ATOM 1581 C CG . PHE A 1 258 ? -50.139 5.391 -26.791 1.00 28.22 ? 258 PHE A CG 1 ATOM 1582 C CD1 . PHE A 1 258 ? -50.353 6.699 -26.391 1.00 26.57 ? 258 PHE A CD1 1 ATOM 1583 C CD2 . PHE A 1 258 ? -50.082 4.399 -25.829 1.00 27.40 ? 258 PHE A CD2 1 ATOM 1584 C CE1 . PHE A 1 258 ? -50.494 7.012 -25.058 1.00 28.34 ? 258 PHE A CE1 1 ATOM 1585 C CE2 . PHE A 1 258 ? -50.222 4.704 -24.496 1.00 30.91 ? 258 PHE A CE2 1 ATOM 1586 C CZ . PHE A 1 258 ? -50.429 6.013 -24.107 1.00 34.62 ? 258 PHE A CZ 1 ATOM 1587 N N . MET A 1 259 ? -46.953 5.330 -27.059 1.00 31.37 ? 259 MET A N 1 ATOM 1588 C CA . MET A 1 259 ? -46.049 4.718 -26.084 1.00 35.92 ? 259 MET A CA 1 ATOM 1589 C C . MET A 1 259 ? -46.173 5.354 -24.701 1.00 33.50 ? 259 MET A C 1 ATOM 1590 O O . MET A 1 259 ? -46.244 6.575 -24.563 1.00 31.35 ? 259 MET A O 1 ATOM 1591 C CB . MET A 1 259 ? -44.587 4.796 -26.534 1.00 32.69 ? 259 MET A CB 1 ATOM 1592 C CG . MET A 1 259 ? -43.649 3.980 -25.645 1.00 30.45 ? 259 MET A CG 1 ATOM 1593 S SD . MET A 1 259 ? -41.921 4.478 -25.692 1.00 30.88 ? 259 MET A SD 1 ATOM 1594 C CE . MET A 1 259 ? -42.015 6.040 -24.826 1.00 31.01 ? 259 MET A CE 1 ATOM 1595 N N . SER A 1 260 ? -46.195 4.510 -23.676 1.00 32.61 ? 260 SER A N 1 ATOM 1596 C CA . SER A 1 260 ? -46.150 4.984 -22.304 1.00 34.58 ? 260 SER A CA 1 ATOM 1597 C C . SER A 1 260 ? -45.084 4.227 -21.524 1.00 34.01 ? 260 SER A C 1 ATOM 1598 O O . SER A 1 260 ? -45.205 3.025 -21.306 1.00 33.24 ? 260 SER A O 1 ATOM 1599 C CB . SER A 1 260 ? -47.512 4.800 -21.637 1.00 36.76 ? 260 SER A CB 1 ATOM 1600 O OG . SER A 1 260 ? -47.412 4.959 -20.232 1.00 34.49 ? 260 SER A OG 1 ATOM 1601 N N . SER A 1 261 ? -44.039 4.934 -21.099 1.00 32.97 ? 261 SER A N 1 ATOM 1602 C CA . SER A 1 261 ? -43.005 4.320 -20.276 1.00 31.55 ? 261 SER A CA 1 ATOM 1603 C C . SER A 1 261 ? -42.979 4.984 -18.911 1.00 33.46 ? 261 SER A C 1 ATOM 1604 O O . SER A 1 261 ? -42.633 6.159 -18.795 1.00 35.40 ? 261 SER A O 1 ATOM 1605 C CB . SER A 1 261 ? -41.628 4.437 -20.933 1.00 28.37 ? 261 SER A CB 1 ATOM 1606 O OG . SER A 1 261 ? -41.066 5.723 -20.743 1.00 24.74 ? 261 SER A OG 1 ATOM 1607 N N . LEU A 1 262 ? -43.352 4.238 -17.876 1.00 32.87 ? 262 LEU A N 1 ATOM 1608 C CA . LEU A 1 262 ? -43.282 4.761 -16.519 1.00 33.26 ? 262 LEU A CA 1 ATOM 1609 C C . LEU A 1 262 ? -41.959 4.341 -15.895 1.00 36.91 ? 262 LEU A C 1 ATOM 1610 O O . LEU A 1 262 ? -41.751 3.169 -15.592 1.00 35.91 ? 262 LEU A O 1 ATOM 1611 C CB . LEU A 1 262 ? -44.453 4.249 -15.676 1.00 32.44 ? 262 LEU A CB 1 ATOM 1612 C CG . LEU A 1 262 ? -44.571 4.821 -14.259 1.00 36.15 ? 262 LEU A CG 1 ATOM 1613 C CD1 . LEU A 1 262 ? -44.869 6.310 -14.307 1.00 34.31 ? 262 LEU A CD1 1 ATOM 1614 C CD2 . LEU A 1 262 ? -45.629 4.088 -13.444 1.00 40.56 ? 262 LEU A CD2 1 ATOM 1615 N N . ILE A 1 263 ? -41.071 5.308 -15.693 1.00 37.14 ? 263 ILE A N 1 ATOM 1616 C CA . ILE A 1 263 ? -39.752 5.024 -15.146 1.00 37.75 ? 263 ILE A CA 1 ATOM 1617 C C . ILE A 1 263 ? -39.693 5.448 -13.686 1.00 43.67 ? 263 ILE A C 1 ATOM 1618 O O . ILE A 1 263 ? -39.887 6.621 -13.365 1.00 45.95 ? 263 ILE A O 1 ATOM 1619 C CB . ILE A 1 263 ? -38.641 5.734 -15.944 1.00 39.72 ? 263 ILE A CB 1 ATOM 1620 C CG1 . ILE A 1 263 ? -38.663 5.283 -17.409 1.00 39.47 ? 263 ILE A CG1 1 ATOM 1621 C CG2 . ILE A 1 263 ? -37.286 5.453 -15.328 1.00 47.23 ? 263 ILE A CG2 1 ATOM 1622 C CD1 . ILE A 1 263 ? -37.590 5.924 -18.274 1.00 40.26 ? 263 ILE A CD1 1 ATOM 1623 N N . SER A 1 264 ? -39.431 4.488 -12.804 1.00 49.21 ? 264 SER A N 1 ATOM 1624 C CA . SER A 1 264 ? -39.424 4.750 -11.368 1.00 54.63 ? 264 SER A CA 1 ATOM 1625 C C . SER A 1 264 ? -38.229 4.125 -10.651 1.00 56.46 ? 264 SER A C 1 ATOM 1626 O O . SER A 1 264 ? -37.911 2.953 -10.853 1.00 50.20 ? 264 SER A O 1 ATOM 1627 C CB . SER A 1 264 ? -40.734 4.274 -10.730 1.00 51.25 ? 264 SER A CB 1 ATOM 1628 O OG . SER A 1 264 ? -40.984 2.906 -11.012 1.00 45.65 ? 264 SER A OG 1 ATOM 1629 N N . LEU A 1 265 ? -37.571 4.929 -9.821 1.00 64.72 ? 265 LEU A N 1 ATOM 1630 C CA . LEU A 1 265 ? -36.475 4.468 -8.974 1.00 66.10 ? 265 LEU A CA 1 ATOM 1631 C C . LEU A 1 265 ? -36.921 4.501 -7.521 1.00 72.24 ? 265 LEU A C 1 ATOM 1632 O O . LEU A 1 265 ? -37.745 5.331 -7.144 1.00 77.26 ? 265 LEU A O 1 ATOM 1633 C CB . LEU A 1 265 ? -35.251 5.375 -9.131 1.00 60.96 ? 265 LEU A CB 1 ATOM 1634 C CG . LEU A 1 265 ? -34.278 5.128 -10.283 1.00 55.03 ? 265 LEU A CG 1 ATOM 1635 C CD1 . LEU A 1 265 ? -33.263 6.255 -10.375 1.00 58.18 ? 265 LEU A CD1 1 ATOM 1636 C CD2 . LEU A 1 265 ? -33.570 3.794 -10.115 1.00 56.80 ? 265 LEU A CD2 1 ATOM 1637 N N . SER A 1 266 ? -36.380 3.604 -6.704 1.00 70.83 ? 266 SER A N 1 ATOM 1638 C CA . SER A 1 266 ? -36.643 3.652 -5.274 1.00 66.84 ? 266 SER A CA 1 ATOM 1639 C C . SER A 1 266 ? -35.878 4.830 -4.687 1.00 69.95 ? 266 SER A C 1 ATOM 1640 O O . SER A 1 266 ? -36.310 5.448 -3.715 1.00 70.97 ? 266 SER A O 1 ATOM 1641 C CB . SER A 1 266 ? -36.216 2.353 -4.592 1.00 60.00 ? 266 SER A CB 1 ATOM 1642 O OG . SER A 1 266 ? -34.804 2.252 -4.534 1.00 66.59 ? 266 SER A OG 1 ATOM 1643 N N . SER A 1 267 ? -34.743 5.140 -5.305 1.00 69.11 ? 267 SER A N 1 ATOM 1644 C CA . SER A 1 267 ? -33.846 6.182 -4.819 1.00 71.00 ? 267 SER A CA 1 ATOM 1645 C C . SER A 1 267 ? -34.046 7.548 -5.484 1.00 70.48 ? 267 SER A C 1 ATOM 1646 O O . SER A 1 267 ? -33.304 8.490 -5.201 1.00 67.00 ? 267 SER A O 1 ATOM 1647 C CB . SER A 1 267 ? -32.394 5.728 -4.974 1.00 76.83 ? 267 SER A CB 1 ATOM 1648 O OG . SER A 1 267 ? -32.188 5.124 -6.240 1.00 77.87 ? 267 SER A OG 1 ATOM 1649 N N . GLY A 1 268 ? -35.041 7.661 -6.359 1.00 75.33 ? 268 GLY A N 1 ATOM 1650 C CA . GLY A 1 268 ? -35.282 8.910 -7.063 1.00 78.49 ? 268 GLY A CA 1 ATOM 1651 C C . GLY A 1 268 ? -36.724 9.141 -7.480 1.00 82.86 ? 268 GLY A C 1 ATOM 1652 O O . GLY A 1 268 ? -37.602 8.324 -7.201 1.00 80.10 ? 268 GLY A O 1 ATOM 1653 N N . LEU A 1 269 ? -36.967 10.267 -8.149 1.00 79.22 ? 269 LEU A N 1 ATOM 1654 C CA . LEU A 1 269 ? -38.308 10.616 -8.611 1.00 70.83 ? 269 LEU A CA 1 ATOM 1655 C C . LEU A 1 269 ? -38.756 9.704 -9.743 1.00 63.23 ? 269 LEU A C 1 ATOM 1656 O O . LEU A 1 269 ? -37.933 9.215 -10.516 1.00 66.51 ? 269 LEU A O 1 ATOM 1657 C CB . LEU A 1 269 ? -38.362 12.065 -9.104 1.00 75.65 ? 269 LEU A CB 1 ATOM 1658 C CG . LEU A 1 269 ? -38.053 13.216 -8.148 1.00 86.21 ? 269 LEU A CG 1 ATOM 1659 C CD1 . LEU A 1 269 ? -38.599 14.518 -8.720 1.00 86.43 ? 269 LEU A CD1 1 ATOM 1660 C CD2 . LEU A 1 269 ? -38.623 12.952 -6.767 1.00 85.73 ? 269 LEU A CD2 1 ATOM 1661 N N . PRO A 1 270 ? -40.068 9.452 -9.831 1.00 58.34 ? 270 PRO A N 1 ATOM 1662 C CA . PRO A 1 270 ? -40.620 8.791 -11.015 1.00 57.66 ? 270 PRO A CA 1 ATOM 1663 C C . PRO A 1 270 ? -40.804 9.783 -12.159 1.00 55.38 ? 270 PRO A C 1 ATOM 1664 O O . PRO A 1 270 ? -41.032 10.966 -11.903 1.00 52.45 ? 270 PRO A O 1 ATOM 1665 C CB . PRO A 1 270 ? -41.984 8.311 -10.527 1.00 56.54 ? 270 PRO A CB 1 ATOM 1666 C CG . PRO A 1 270 ? -42.378 9.321 -9.502 1.00 59.31 ? 270 PRO A CG 1 ATOM 1667 C CD . PRO A 1 270 ? -41.100 9.721 -8.813 1.00 64.33 ? 270 PRO A CD 1 ATOM 1668 N N . ILE A 1 271 ? -40.708 9.307 -13.397 1.00 52.39 ? 271 ILE A N 1 ATOM 1669 C CA . ILE A 1 271 ? -41.106 10.093 -14.562 1.00 44.42 ? 271 ILE A CA 1 ATOM 1670 C C . ILE A 1 271 ? -41.860 9.194 -15.530 1.00 40.82 ? 271 ILE A C 1 ATOM 1671 O O . ILE A 1 271 ? -41.613 7.989 -15.588 1.00 37.45 ? 271 ILE A O 1 ATOM 1672 C CB . ILE A 1 271 ? -39.908 10.732 -15.305 1.00 48.94 ? 271 ILE A CB 1 ATOM 1673 C CG1 . ILE A 1 271 ? -38.930 9.661 -15.793 1.00 45.85 ? 271 ILE A CG1 1 ATOM 1674 C CG2 . ILE A 1 271 ? -39.199 11.750 -14.428 1.00 66.47 ? 271 ILE A CG2 1 ATOM 1675 C CD1 . ILE A 1 271 ? -37.807 10.214 -16.647 1.00 48.54 ? 271 ILE A CD1 1 ATOM 1676 N N . GLU A 1 272 ? -42.787 9.773 -16.285 1.00 43.44 ? 272 GLU A N 1 ATOM 1677 C CA . GLU A 1 272 ? -43.524 9.005 -17.282 1.00 41.27 ? 272 GLU A CA 1 ATOM 1678 C C . GLU A 1 272 ? -43.384 9.628 -18.664 1.00 37.59 ? 272 GLU A C 1 ATOM 1679 O O . GLU A 1 272 ? -43.771 10.777 -18.879 1.00 35.58 ? 272 GLU A O 1 ATOM 1680 C CB . GLU A 1 272 ? -45.004 8.894 -16.911 1.00 41.95 ? 272 GLU A CB 1 ATOM 1681 C CG . GLU A 1 272 ? -45.752 7.826 -17.697 1.00 42.47 ? 272 GLU A CG 1 ATOM 1682 C CD . GLU A 1 272 ? -47.257 7.979 -17.604 1.00 46.64 ? 272 GLU A CD 1 ATOM 1683 O OE1 . GLU A 1 272 ? -47.725 9.130 -17.481 1.00 48.11 ? 272 GLU A OE1 1 ATOM 1684 O OE2 . GLU A 1 272 ? -47.970 6.954 -17.656 1.00 42.41 ? 272 GLU A OE2 1 ATOM 1685 N N . LEU A 1 273 ? -42.824 8.868 -19.598 1.00 35.15 ? 273 LEU A N 1 ATOM 1686 C CA . LEU A 1 273 ? -42.702 9.330 -20.974 1.00 31.52 ? 273 LEU A CA 1 ATOM 1687 C C . LEU A 1 273 ? -43.921 8.898 -21.780 1.00 36.86 ? 273 LEU A C 1 ATOM 1688 O O . LEU A 1 273 ? -44.269 7.716 -21.815 1.00 37.87 ? 273 LEU A O 1 ATOM 1689 C CB . LEU A 1 273 ? -41.422 8.795 -21.616 1.00 29.09 ? 273 LEU A CB 1 ATOM 1690 C CG . LEU A 1 273 ? -41.061 9.378 -22.982 1.00 33.69 ? 273 LEU A CG 1 ATOM 1691 C CD1 . LEU A 1 273 ? -40.917 10.885 -22.889 1.00 37.69 ? 273 LEU A CD1 1 ATOM 1692 C CD2 . LEU A 1 273 ? -39.786 8.752 -23.532 1.00 40.87 ? 273 LEU A CD2 1 ATOM 1693 N N . ILE A 1 274 ? -44.570 9.863 -22.423 1.00 36.69 ? 274 ILE A N 1 ATOM 1694 C CA . ILE A 1 274 ? -45.756 9.594 -23.227 1.00 28.98 ? 274 ILE A CA 1 ATOM 1695 C C . ILE A 1 274 ? -45.567 10.072 -24.667 1.00 31.60 ? 274 ILE A C 1 ATOM 1696 O O . ILE A 1 274 ? -45.166 11.210 -24.904 1.00 35.56 ? 274 ILE A O 1 ATOM 1697 C CB . ILE A 1 274 ? -47.014 10.232 -22.594 1.00 27.76 ? 274 ILE A CB 1 ATOM 1698 C CG1 . ILE A 1 274 ? -47.545 9.336 -21.473 1.00 31.81 ? 274 ILE A CG1 1 ATOM 1699 C CG2 . ILE A 1 274 ? -48.094 10.462 -23.634 1.00 32.08 ? 274 ILE A CG2 1 ATOM 1700 C CD1 . ILE A 1 274 ? -48.830 9.825 -20.844 1.00 36.99 ? 274 ILE A CD1 1 ATOM 1701 N N . VAL A 1 275 ? -45.840 9.187 -25.623 1.00 31.00 ? 275 VAL A N 1 ATOM 1702 C CA . VAL A 1 275 ? -45.727 9.518 -27.040 1.00 30.52 ? 275 VAL A CA 1 ATOM 1703 C C . VAL A 1 275 ? -47.072 9.346 -27.748 1.00 29.05 ? 275 VAL A C 1 ATOM 1704 O O . VAL A 1 275 ? -47.648 8.260 -27.746 1.00 26.84 ? 275 VAL A O 1 ATOM 1705 C CB . VAL A 1 275 ? -44.662 8.649 -27.731 1.00 30.16 ? 275 VAL A CB 1 ATOM 1706 C CG1 . VAL A 1 275 ? -44.445 9.102 -29.162 1.00 35.17 ? 275 VAL A CG1 1 ATOM 1707 C CG2 . VAL A 1 275 ? -43.364 8.716 -26.961 1.00 34.47 ? 275 VAL A CG2 1 ATOM 1708 N N . VAL A 1 276 ? -47.569 10.429 -28.340 1.00 29.44 ? 276 VAL A N 1 ATOM 1709 C CA . VAL A 1 276 ? -48.843 10.420 -29.059 1.00 32.52 ? 276 VAL A CA 1 ATOM 1710 C C . VAL A 1 276 ? -48.649 11.089 -30.423 1.00 38.15 ? 276 VAL A C 1 ATOM 1711 O O . VAL A 1 276 ? -47.718 11.878 -30.586 1.00 40.24 ? 276 VAL A O 1 ATOM 1712 C CB . VAL A 1 276 ? -49.950 11.137 -28.248 1.00 33.24 ? 276 VAL A CB 1 ATOM 1713 C CG1 . VAL A 1 276 ? -50.336 10.312 -27.031 1.00 29.93 ? 276 VAL A CG1 1 ATOM 1714 C CG2 . VAL A 1 276 ? -49.495 12.523 -27.829 1.00 37.14 ? 276 VAL A CG2 1 ATOM 1715 N N . PRO A 1 277 ? -49.508 10.767 -31.412 1.00 34.43 ? 277 PRO A N 1 ATOM 1716 C CA . PRO A 1 277 ? -49.342 11.328 -32.762 1.00 36.90 ? 277 PRO A CA 1 ATOM 1717 C C . PRO A 1 277 ? -49.327 12.858 -32.777 1.00 42.11 ? 277 PRO A C 1 ATOM 1718 O O . PRO A 1 277 ? -49.928 13.477 -31.901 1.00 45.79 ? 277 PRO A O 1 ATOM 1719 C CB . PRO A 1 277 ? -50.567 10.794 -33.506 1.00 34.59 ? 277 PRO A CB 1 ATOM 1720 C CG . PRO A 1 277 ? -50.883 9.517 -32.813 1.00 29.53 ? 277 PRO A CG 1 ATOM 1721 C CD . PRO A 1 277 ? -50.622 9.803 -31.361 1.00 28.79 ? 277 PRO A CD 1 ATOM 1722 N N . HIS A 1 278 ? -48.654 13.444 -33.765 1.00 43.89 ? 278 HIS A N 1 ATOM 1723 C CA . HIS A 1 278 ? -48.393 14.886 -33.803 1.00 44.37 ? 278 HIS A CA 1 ATOM 1724 C C . HIS A 1 278 ? -49.650 15.748 -33.716 1.00 48.03 ? 278 HIS A C 1 ATOM 1725 O O . HIS A 1 278 ? -49.596 16.896 -33.276 1.00 52.87 ? 278 HIS A O 1 ATOM 1726 C CB . HIS A 1 278 ? -47.617 15.252 -35.069 1.00 45.18 ? 278 HIS A CB 1 ATOM 1727 C CG . HIS A 1 278 ? -48.429 15.152 -36.323 1.00 47.40 ? 278 HIS A CG 1 ATOM 1728 N ND1 . HIS A 1 278 ? -48.766 13.945 -36.896 1.00 50.26 ? 278 HIS A ND1 1 ATOM 1729 C CD2 . HIS A 1 278 ? -48.973 16.108 -37.111 1.00 45.42 ? 278 HIS A CD2 1 ATOM 1730 C CE1 . HIS A 1 278 ? -49.484 14.162 -37.984 1.00 48.11 ? 278 HIS A CE1 1 ATOM 1731 N NE2 . HIS A 1 278 ? -49.624 15.466 -38.137 1.00 46.58 ? 278 HIS A NE2 1 ATOM 1732 N N . THR A 1 279 ? -50.776 15.190 -34.141 1.00 44.83 ? 279 THR A N 1 ATOM 1733 C CA . THR A 1 279 ? -52.040 15.911 -34.123 1.00 43.94 ? 279 THR A CA 1 ATOM 1734 C C . THR A 1 279 ? -52.578 16.075 -32.702 1.00 52.09 ? 279 THR A C 1 ATOM 1735 O O . THR A 1 279 ? -53.033 17.154 -32.325 1.00 59.89 ? 279 THR A O 1 ATOM 1736 C CB . THR A 1 279 ? -53.099 15.191 -34.978 1.00 47.94 ? 279 THR A CB 1 ATOM 1737 O OG1 . THR A 1 279 ? -53.357 13.893 -34.427 1.00 56.90 ? 279 THR A OG1 1 ATOM 1738 C CG2 . THR A 1 279 ? -52.613 15.038 -36.411 1.00 46.19 ? 279 THR A CG2 1 ATOM 1739 N N . VAL A 1 280 ? -52.516 14.998 -31.923 1.00 51.57 ? 280 VAL A N 1 ATOM 1740 C CA . VAL A 1 280 ? -53.108 14.951 -30.584 1.00 48.89 ? 280 VAL A CA 1 ATOM 1741 C C . VAL A 1 280 ? -52.583 16.009 -29.608 1.00 52.46 ? 280 VAL A C 1 ATOM 1742 O O . VAL A 1 280 ? -51.374 16.168 -29.432 1.00 51.89 ? 280 VAL A O 1 ATOM 1743 C CB . VAL A 1 280 ? -52.944 13.543 -29.956 1.00 39.50 ? 280 VAL A CB 1 ATOM 1744 C CG1 . VAL A 1 280 ? -53.045 13.602 -28.439 1.00 37.99 ? 280 VAL A CG1 1 ATOM 1745 C CG2 . VAL A 1 280 ? -53.981 12.591 -30.527 1.00 41.30 ? 280 VAL A CG2 1 ATOM 1746 N N . LYS A 1 281 ? -53.509 16.731 -28.984 1.00 54.39 ? 281 LYS A N 1 ATOM 1747 C CA . LYS A 1 281 ? -53.176 17.650 -27.903 1.00 52.97 ? 281 LYS A CA 1 ATOM 1748 C C . LYS A 1 281 ? -53.610 17.036 -26.581 1.00 53.25 ? 281 LYS A C 1 ATOM 1749 O O . LYS A 1 281 ? -54.643 16.373 -26.512 1.00 54.61 ? 281 LYS A O 1 ATOM 1750 C CB . LYS A 1 281 ? -53.882 18.993 -28.097 1.00 52.16 ? 281 LYS A CB 1 ATOM 1751 C CG . LYS A 1 281 ? -53.444 19.764 -29.332 1.00 60.83 ? 281 LYS A CG 1 ATOM 1752 C CD . LYS A 1 281 ? -54.148 21.117 -29.449 1.00 65.13 ? 281 LYS A CD 1 ATOM 1753 C CE . LYS A 1 281 ? -53.548 22.175 -28.521 1.00 62.67 ? 281 LYS A CE 1 ATOM 1754 N NZ . LYS A 1 281 ? -53.901 21.993 -27.084 1.00 52.27 ? 281 LYS A NZ 1 ATOM 1755 N N . LEU A 1 282 ? -52.822 17.252 -25.533 1.00 57.58 ? 282 LEU A N 1 ATOM 1756 C CA . LEU A 1 282 ? -53.184 16.772 -24.201 1.00 59.21 ? 282 LEU A CA 1 ATOM 1757 C C . LEU A 1 282 ? -53.401 17.923 -23.221 1.00 58.12 ? 282 LEU A C 1 ATOM 1758 O O . LEU A 1 282 ? -52.756 18.965 -23.321 1.00 65.94 ? 282 LEU A O 1 ATOM 1759 C CB . LEU A 1 282 ? -52.129 15.801 -23.666 1.00 52.30 ? 282 LEU A CB 1 ATOM 1760 C CG . LEU A 1 282 ? -52.208 14.375 -24.210 1.00 47.15 ? 282 LEU A CG 1 ATOM 1761 C CD1 . LEU A 1 282 ? -51.135 13.504 -23.589 1.00 45.67 ? 282 LEU A CD1 1 ATOM 1762 C CD2 . LEU A 1 282 ? -53.582 13.789 -23.948 1.00 49.31 ? 282 LEU A CD2 1 ATOM 1763 N N . ASN A 1 283 ? -54.318 17.730 -22.278 1.00 47.45 ? 283 ASN A N 1 ATOM 1764 C CA . ASN A 1 283 ? -54.607 18.748 -21.275 1.00 57.20 ? 283 ASN A CA 1 ATOM 1765 C C . ASN A 1 283 ? -54.069 18.357 -19.902 1.00 59.14 ? 283 ASN A C 1 ATOM 1766 O O . ASN A 1 283 ? -54.448 17.323 -19.353 1.00 57.50 ? 283 ASN A O 1 ATOM 1767 C CB . ASN A 1 283 ? -56.116 18.994 -21.186 1.00 72.13 ? 283 ASN A CB 1 ATOM 1768 C CG . ASN A 1 283 ? -56.498 20.429 -21.503 1.00 74.01 ? 283 ASN A CG 1 ATOM 1769 O OD1 . ASN A 1 283 ? -55.663 21.332 -21.461 1.00 82.67 ? 283 ASN A OD1 1 ATOM 1770 N ND2 . ASN A 1 283 ? -57.772 20.646 -21.813 1.00 60.55 ? 283 ASN A ND2 1 ATOM 1771 N N . ALA A 1 284 ? -53.191 19.187 -19.346 1.00 60.15 ? 284 ALA A N 1 ATOM 1772 C CA . ALA A 1 284 ? -52.641 18.934 -18.019 1.00 56.92 ? 284 ALA A CA 1 ATOM 1773 C C . ALA A 1 284 ? -53.689 19.175 -16.939 1.00 56.37 ? 284 ALA A C 1 ATOM 1774 O O . ALA A 1 284 ? -54.622 19.954 -17.132 1.00 56.74 ? 284 ALA A O 1 ATOM 1775 C CB . ALA A 1 284 ? -51.426 19.808 -17.773 1.00 57.85 ? 284 ALA A CB 1 ATOM 1776 N N . VAL A 1 285 ? -53.524 18.513 -15.799 1.00 55.51 ? 285 VAL A N 1 ATOM 1777 C CA . VAL A 1 285 ? -54.436 18.695 -14.678 1.00 53.60 ? 285 VAL A CA 1 ATOM 1778 C C . VAL A 1 285 ? -53.813 19.639 -13.659 1.00 54.00 ? 285 VAL A C 1 ATOM 1779 O O . VAL A 1 285 ? -52.846 19.288 -12.985 1.00 55.18 ? 285 VAL A O 1 ATOM 1780 C CB . VAL A 1 285 ? -54.760 17.355 -13.986 1.00 44.06 ? 285 VAL A CB 1 ATOM 1781 C CG1 . VAL A 1 285 ? -55.659 17.582 -12.790 1.00 43.99 ? 285 VAL A CG1 1 ATOM 1782 C CG2 . VAL A 1 285 ? -55.416 16.398 -14.961 1.00 45.48 ? 285 VAL A CG2 1 ATOM 1783 N N . THR A 1 286 ? -54.369 20.842 -13.554 1.00 54.49 ? 286 THR A N 1 ATOM 1784 C CA . THR A 1 286 ? -53.890 21.822 -12.587 1.00 58.48 ? 286 THR A CA 1 ATOM 1785 C C . THR A 1 286 ? -55.009 22.223 -11.636 1.00 61.95 ? 286 THR A C 1 ATOM 1786 O O . THR A 1 286 ? -56.147 21.778 -11.786 1.00 59.60 ? 286 THR A O 1 ATOM 1787 C CB . THR A 1 286 ? -53.319 23.074 -13.280 1.00 60.98 ? 286 THR A CB 1 ATOM 1788 O OG1 . THR A 1 286 ? -54.161 23.444 -14.378 1.00 58.13 ? 286 THR A OG1 1 ATOM 1789 C CG2 . THR A 1 286 ? -51.920 22.799 -13.800 1.00 64.53 ? 286 THR A CG2 1 ATOM 1790 N N . SER A 1 287 ? -54.686 23.070 -10.664 1.00 65.65 ? 287 SER A N 1 ATOM 1791 C CA . SER A 1 287 ? -55.648 23.446 -9.635 1.00 62.99 ? 287 SER A CA 1 ATOM 1792 C C . SER A 1 287 ? -56.644 24.475 -10.151 1.00 64.53 ? 287 SER A C 1 ATOM 1793 O O . SER A 1 287 ? -57.768 24.561 -9.655 1.00 70.69 ? 287 SER A O 1 ATOM 1794 C CB . SER A 1 287 ? -54.934 23.975 -8.388 1.00 57.39 ? 287 SER A CB 1 ATOM 1795 O OG . SER A 1 287 ? -54.208 25.158 -8.669 1.00 61.76 ? 287 SER A OG 1 ATOM 1796 N N . ASP A 1 288 ? -56.225 25.250 -11.147 1.00 61.62 ? 288 ASP A N 1 ATOM 1797 C CA . ASP A 1 288 ? -57.082 26.272 -11.735 1.00 65.77 ? 288 ASP A CA 1 ATOM 1798 C C . ASP A 1 288 ? -58.355 25.640 -12.291 1.00 71.89 ? 288 ASP A C 1 ATOM 1799 O O . ASP A 1 288 ? -58.306 24.671 -13.043 1.00 73.79 ? 288 ASP A O 1 ATOM 1800 C CB . ASP A 1 288 ? -56.329 27.080 -12.806 1.00 73.95 ? 288 ASP A CB 1 ATOM 1801 C CG . ASP A 1 288 ? -56.328 26.409 -14.172 1.00 80.07 ? 288 ASP A CG 1 ATOM 1802 O OD1 . ASP A 1 288 ? -55.626 25.391 -14.346 1.00 82.09 ? 288 ASP A OD1 1 ATOM 1803 O OD2 . ASP A 1 288 ? -57.023 26.913 -15.079 1.00 77.71 ? 288 ASP A OD2 1 ATOM 1804 N N . THR A 1 289 ? -59.496 26.183 -11.883 1.00 73.36 ? 289 THR A N 1 ATOM 1805 C CA . THR A 1 289 ? -60.793 25.632 -12.257 1.00 71.39 ? 289 THR A CA 1 ATOM 1806 C C . THR A 1 289 ? -61.302 26.257 -13.552 1.00 78.61 ? 289 THR A C 1 ATOM 1807 O O . THR A 1 289 ? -62.418 25.983 -13.991 1.00 76.88 ? 289 THR A O 1 ATOM 1808 C CB . THR A 1 289 ? -61.818 25.821 -11.126 1.00 64.90 ? 289 THR A CB 1 ATOM 1809 O OG1 . THR A 1 289 ? -63.134 25.947 -11.678 1.00 68.13 ? 289 THR A OG1 1 ATOM 1810 C CG2 . THR A 1 289 ? -61.488 27.068 -10.326 1.00 70.93 ? 289 THR A CG2 1 ATOM 1811 N N . THR A 1 290 ? -60.468 27.096 -14.158 1.00 81.32 ? 290 THR A N 1 ATOM 1812 C CA . THR A 1 290 ? -60.805 27.738 -15.420 1.00 76.26 ? 290 THR A CA 1 ATOM 1813 C C . THR A 1 290 ? -60.905 26.717 -16.544 1.00 77.49 ? 290 THR A C 1 ATOM 1814 O O . THR A 1 290 ? -60.363 25.616 -16.452 1.00 80.72 ? 290 THR A O 1 ATOM 1815 C CB . THR A 1 290 ? -59.769 28.801 -15.813 1.00 76.77 ? 290 THR A CB 1 ATOM 1816 O OG1 . THR A 1 290 ? -58.707 28.812 -14.853 1.00 85.54 ? 290 THR A OG1 1 ATOM 1817 C CG2 . THR A 1 290 ? -60.412 30.175 -15.867 1.00 72.76 ? 290 THR A CG2 1 ATOM 1818 N N . TRP A 1 291 ? -61.603 27.102 -17.604 1.00 79.73 ? 291 TRP A N 1 ATOM 1819 C CA . TRP A 1 291 ? -61.828 26.236 -18.754 1.00 86.73 ? 291 TRP A CA 1 ATOM 1820 C C . TRP A 1 291 ? -60.694 26.323 -19.771 1.00 85.50 ? 291 TRP A C 1 ATOM 1821 O O . TRP A 1 291 ? -60.766 25.730 -20.847 1.00 76.14 ? 291 TRP A O 1 ATOM 1822 C CB . TRP A 1 291 ? -63.190 26.530 -19.395 1.00 89.39 ? 291 TRP A CB 1 ATOM 1823 C CG . TRP A 1 291 ? -63.262 27.691 -20.369 1.00 90.50 ? 291 TRP A CG 1 ATOM 1824 C CD1 . TRP A 1 291 ? -63.960 27.712 -21.540 1.00 93.70 ? 291 TRP A CD1 1 ATOM 1825 C CD2 . TRP A 1 291 ? -62.646 28.988 -20.251 1.00 94.37 ? 291 TRP A CD2 1 ATOM 1826 N NE1 . TRP A 1 291 ? -63.820 28.927 -22.157 1.00 100.81 ? 291 TRP A NE1 1 ATOM 1827 C CE2 . TRP A 1 291 ? -63.015 29.727 -21.392 1.00 93.78 ? 291 TRP A CE2 1 ATOM 1828 C CE3 . TRP A 1 291 ? -61.816 29.591 -19.300 1.00 99.71 ? 291 TRP A CE3 1 ATOM 1829 C CZ2 . TRP A 1 291 ? -62.585 31.036 -21.607 1.00 91.81 ? 291 TRP A CZ2 1 ATOM 1830 C CZ3 . TRP A 1 291 ? -61.391 30.889 -19.516 1.00 106.35 ? 291 TRP A CZ3 1 ATOM 1831 C CH2 . TRP A 1 291 ? -61.778 31.598 -20.659 1.00 98.45 ? 291 TRP A CH2 1 ATOM 1832 N N . PHE A 1 292 ? -59.653 27.074 -19.421 1.00 90.07 ? 292 PHE A N 1 ATOM 1833 C CA . PHE A 1 292 ? -58.493 27.239 -20.289 1.00 82.63 ? 292 PHE A CA 1 ATOM 1834 C C . PHE A 1 292 ? -57.638 25.978 -20.367 1.00 76.43 ? 292 PHE A C 1 ATOM 1835 O O . PHE A 1 292 ? -57.937 24.966 -19.730 1.00 65.64 ? 292 PHE A O 1 ATOM 1836 C CB . PHE A 1 292 ? -57.636 28.421 -19.828 1.00 74.55 ? 292 PHE A CB 1 ATOM 1837 C CG . PHE A 1 292 ? -57.981 29.718 -20.504 1.00 78.34 ? 292 PHE A CG 1 ATOM 1838 C CD1 . PHE A 1 292 ? -58.633 29.728 -21.726 1.00 82.28 ? 292 PHE A CD1 1 ATOM 1839 C CD2 . PHE A 1 292 ? -57.647 30.926 -19.922 1.00 77.07 ? 292 PHE A CD2 1 ATOM 1840 C CE1 . PHE A 1 292 ? -58.948 30.923 -22.350 1.00 82.17 ? 292 PHE A CE1 1 ATOM 1841 C CE2 . PHE A 1 292 ? -57.960 32.124 -20.537 1.00 82.00 ? 292 PHE A CE2 1 ATOM 1842 C CZ . PHE A 1 292 ? -58.611 32.122 -21.753 1.00 81.47 ? 292 PHE A CZ 1 ATOM 1843 N N . GLN A 1 293 ? -56.568 26.055 -21.152 1.00 80.05 ? 293 GLN A N 1 ATOM 1844 C CA . GLN A 1 293 ? -55.732 24.893 -21.425 1.00 79.76 ? 293 GLN A CA 1 ATOM 1845 C C . GLN A 1 293 ? -54.262 25.131 -21.082 1.00 72.48 ? 293 GLN A C 1 ATOM 1846 O O . GLN A 1 293 ? -53.701 26.185 -21.382 1.00 69.74 ? 293 GLN A O 1 ATOM 1847 C CB . GLN A 1 293 ? -55.875 24.479 -22.886 1.00 73.58 ? 293 GLN A CB 1 ATOM 1848 N N . LEU A 1 294 ? -53.645 24.142 -20.445 1.00 65.21 ? 294 LEU A N 1 ATOM 1849 C CA . LEU A 1 294 ? -52.223 24.196 -20.143 1.00 62.85 ? 294 LEU A CA 1 ATOM 1850 C C . LEU A 1 294 ? -51.568 22.918 -20.653 1.00 66.96 ? 294 LEU A C 1 ATOM 1851 O O . LEU A 1 294 ? -51.877 21.826 -20.179 1.00 62.37 ? 294 LEU A O 1 ATOM 1852 C CB . LEU A 1 294 ? -52.003 24.354 -18.636 1.00 64.08 ? 294 LEU A CB 1 ATOM 1853 C CG . LEU A 1 294 ? -50.674 24.963 -18.188 1.00 64.37 ? 294 LEU A CG 1 ATOM 1854 C CD1 . LEU A 1 294 ? -50.465 26.312 -18.849 1.00 71.36 ? 294 LEU A CD1 1 ATOM 1855 C CD2 . LEU A 1 294 ? -50.629 25.103 -16.675 1.00 64.96 ? 294 LEU A CD2 1 ATOM 1856 N N . ASN A 1 295 ? -50.678 23.051 -21.631 1.00 70.65 ? 295 ASN A N 1 ATOM 1857 C CA . ASN A 1 295 ? -50.028 21.888 -22.229 1.00 57.83 ? 295 ASN A CA 1 ATOM 1858 C C . ASN A 1 295 ? -48.894 21.332 -21.375 1.00 58.56 ? 295 ASN A C 1 ATOM 1859 O O . ASN A 1 295 ? -47.932 22.042 -21.081 1.00 59.50 ? 295 ASN A O 1 ATOM 1860 C CB . ASN A 1 295 ? -49.525 22.210 -23.638 1.00 50.05 ? 295 ASN A CB 1 ATOM 1861 C CG . ASN A 1 295 ? -50.606 22.054 -24.691 1.00 54.01 ? 295 ASN A CG 1 ATOM 1862 O OD1 . ASN A 1 295 ? -50.750 20.990 -25.294 1.00 52.35 ? 295 ASN A OD1 1 ATOM 1863 N ND2 . ASN A 1 295 ? -51.373 23.114 -24.917 1.00 55.96 ? 295 ASN A ND2 1 ATOM 1864 N N . PRO A 1 296 ? -49.006 20.050 -20.987 1.00 60.41 ? 296 PRO A N 1 ATOM 1865 C CA . PRO A 1 296 ? -48.038 19.328 -20.153 1.00 61.41 ? 296 PRO A CA 1 ATOM 1866 C C . PRO A 1 296 ? -46.636 19.373 -20.751 1.00 64.00 ? 296 PRO A C 1 ATOM 1867 O O . PRO A 1 296 ? -46.508 19.526 -21.966 1.00 68.65 ? 296 PRO A O 1 ATOM 1868 C CB . PRO A 1 296 ? -48.579 17.889 -20.144 1.00 55.86 ? 296 PRO A CB 1 ATOM 1869 C CG . PRO A 1 296 ? -49.541 17.816 -21.286 1.00 59.03 ? 296 PRO A CG 1 ATOM 1870 C CD . PRO A 1 296 ? -50.124 19.186 -21.396 1.00 59.89 ? 296 PRO A CD 1 ATOM 1871 N N . PRO A 1 297 ? -45.598 19.250 -19.906 1.00 60.23 ? 297 PRO A N 1 ATOM 1872 C CA . PRO A 1 297 ? -44.203 19.414 -20.332 1.00 56.44 ? 297 PRO A CA 1 ATOM 1873 C C . PRO A 1 297 ? -43.832 18.565 -21.542 1.00 54.40 ? 297 PRO A C 1 ATOM 1874 O O . PRO A 1 297 ? -44.118 17.368 -21.572 1.00 53.38 ? 297 PRO A O 1 ATOM 1875 C CB . PRO A 1 297 ? -43.417 18.931 -19.116 1.00 60.74 ? 297 PRO A CB 1 ATOM 1876 C CG . PRO A 1 297 ? -44.298 19.245 -17.965 1.00 68.91 ? 297 PRO A CG 1 ATOM 1877 C CD . PRO A 1 297 ? -45.698 18.998 -18.456 1.00 61.72 ? 297 PRO A CD 1 ATOM 1878 N N . GLY A 1 298 ? -43.197 19.197 -22.526 1.00 60.16 ? 298 GLY A N 1 ATOM 1879 C CA . GLY A 1 298 ? -42.786 18.535 -23.750 1.00 61.96 ? 298 GLY A CA 1 ATOM 1880 C C . GLY A 1 298 ? -42.450 19.557 -24.820 1.00 64.17 ? 298 GLY A C 1 ATOM 1881 O O . GLY A 1 298 ? -42.760 20.737 -24.667 1.00 71.71 ? 298 GLY A O 1 ATOM 1882 N N . PRO A 1 299 ? -41.822 19.109 -25.919 1.00 53.63 ? 299 PRO A N 1 ATOM 1883 C CA . PRO A 1 299 ? -41.433 20.011 -27.007 1.00 47.49 ? 299 PRO A CA 1 ATOM 1884 C C . PRO A 1 299 ? -42.619 20.360 -27.884 1.00 47.39 ? 299 PRO A C 1 ATOM 1885 O O . PRO A 1 299 ? -43.737 19.933 -27.599 1.00 58.50 ? 299 PRO A O 1 ATOM 1886 C CB . PRO A 1 299 ? -40.456 19.160 -27.816 1.00 50.80 ? 299 PRO A CB 1 ATOM 1887 C CG . PRO A 1 299 ? -40.957 17.770 -27.627 1.00 49.94 ? 299 PRO A CG 1 ATOM 1888 C CD . PRO A 1 299 ? -41.445 17.713 -26.202 1.00 49.38 ? 299 PRO A CD 1 ATOM 1889 N N . ASP A 1 300 ? -42.378 21.126 -28.942 1.00 44.92 ? 300 ASP A N 1 ATOM 1890 C CA . ASP A 1 300 ? -43.394 21.339 -29.961 1.00 51.13 ? 300 ASP A CA 1 ATOM 1891 C C . ASP A 1 300 ? -43.652 19.998 -30.643 1.00 48.85 ? 300 ASP A C 1 ATOM 1892 O O . ASP A 1 300 ? -42.818 19.095 -30.563 1.00 50.64 ? 300 ASP A O 1 ATOM 1893 C CB . ASP A 1 300 ? -42.925 22.385 -30.979 1.00 57.37 ? 300 ASP A CB 1 ATOM 1894 C CG . ASP A 1 300 ? -43.107 23.809 -30.483 1.00 61.46 ? 300 ASP A CG 1 ATOM 1895 O OD1 . ASP A 1 300 ? -44.201 24.376 -30.687 1.00 57.38 ? 300 ASP A OD1 1 ATOM 1896 O OD2 . ASP A 1 300 ? -42.153 24.363 -29.899 1.00 68.58 ? 300 ASP A OD2 1 ATOM 1897 N N . PRO A 1 301 ? -44.810 19.849 -31.304 1.00 41.53 ? 301 PRO A N 1 ATOM 1898 C CA . PRO A 1 301 ? -45.055 18.571 -31.979 1.00 43.33 ? 301 PRO A CA 1 ATOM 1899 C C . PRO A 1 301 ? -44.130 18.402 -33.178 1.00 52.33 ? 301 PRO A C 1 ATOM 1900 O O . PRO A 1 301 ? -43.687 19.396 -33.755 1.00 55.19 ? 301 PRO A O 1 ATOM 1901 C CB . PRO A 1 301 ? -46.506 18.700 -32.446 1.00 42.32 ? 301 PRO A CB 1 ATOM 1902 C CG . PRO A 1 301 ? -46.712 20.167 -32.608 1.00 43.28 ? 301 PRO A CG 1 ATOM 1903 C CD . PRO A 1 301 ? -45.921 20.798 -31.499 1.00 41.98 ? 301 PRO A CD 1 ATOM 1904 N N . GLY A 1 302 ? -43.832 17.160 -33.539 1.00 51.22 ? 302 GLY A N 1 ATOM 1905 C CA . GLY A 1 302 ? -42.983 16.896 -34.683 1.00 43.10 ? 302 GLY A CA 1 ATOM 1906 C C . GLY A 1 302 ? -43.785 16.652 -35.941 1.00 47.47 ? 302 GLY A C 1 ATOM 1907 O O . GLY A 1 302 ? -44.996 16.859 -35.962 1.00 51.64 ? 302 GLY A O 1 ATOM 1908 N N . PRO A 1 303 ? -43.106 16.219 -37.008 1.00 50.64 ? 303 PRO A N 1 ATOM 1909 C CA . PRO A 1 303 ? -43.735 15.893 -38.290 1.00 52.14 ? 303 PRO A CA 1 ATOM 1910 C C . PRO A 1 303 ? -44.555 14.620 -38.169 1.00 50.97 ? 303 PRO A C 1 ATOM 1911 O O . PRO A 1 303 ? -45.479 14.394 -38.951 1.00 54.42 ? 303 PRO A O 1 ATOM 1912 C CB . PRO A 1 303 ? -42.536 15.641 -39.216 1.00 64.80 ? 303 PRO A CB 1 ATOM 1913 C CG . PRO A 1 303 ? -41.336 16.150 -38.473 1.00 62.90 ? 303 PRO A CG 1 ATOM 1914 C CD . PRO A 1 303 ? -41.655 15.986 -37.036 1.00 59.92 ? 303 PRO A CD 1 ATOM 1915 N N . SER A 1 304 ? -44.207 13.799 -37.185 1.00 51.22 ? 304 SER A N 1 ATOM 1916 C CA . SER A 1 304 ? -44.831 12.496 -36.998 1.00 52.99 ? 304 SER A CA 1 ATOM 1917 C C . SER A 1 304 ? -45.504 12.375 -35.634 1.00 48.05 ? 304 SER A C 1 ATOM 1918 O O . SER A 1 304 ? -46.719 12.202 -35.552 1.00 44.64 ? 304 SER A O 1 ATOM 1919 C CB . SER A 1 304 ? -43.791 11.387 -37.171 1.00 51.51 ? 304 SER A CB 1 ATOM 1920 O OG . SER A 1 304 ? -42.641 11.651 -36.383 1.00 54.56 ? 304 SER A OG 1 ATOM 1921 N N . TYR A 1 305 ? -44.710 12.448 -34.568 1.00 45.38 ? 305 TYR A N 1 ATOM 1922 C CA . TYR A 1 305 ? -45.237 12.294 -33.213 1.00 41.88 ? 305 TYR A CA 1 ATOM 1923 C C . TYR A 1 305 ? -45.078 13.548 -32.367 1.00 48.74 ? 305 TYR A C 1 ATOM 1924 O O . TYR A 1 305 ? -44.190 14.367 -32.606 1.00 54.07 ? 305 TYR A O 1 ATOM 1925 C CB . TYR A 1 305 ? -44.541 11.142 -32.489 1.00 36.56 ? 305 TYR A CB 1 ATOM 1926 C CG . TYR A 1 305 ? -44.517 9.858 -33.264 1.00 32.12 ? 305 TYR A CG 1 ATOM 1927 C CD1 . TYR A 1 305 ? -45.591 9.482 -34.051 1.00 35.97 ? 305 TYR A CD1 1 ATOM 1928 C CD2 . TYR A 1 305 ? -43.414 9.023 -33.213 1.00 37.31 ? 305 TYR A CD2 1 ATOM 1929 C CE1 . TYR A 1 305 ? -45.569 8.312 -34.765 1.00 41.03 ? 305 TYR A CE1 1 ATOM 1930 C CE2 . TYR A 1 305 ? -43.383 7.851 -33.923 1.00 38.76 ? 305 TYR A CE2 1 ATOM 1931 C CZ . TYR A 1 305 ? -44.462 7.501 -34.696 1.00 36.79 ? 305 TYR A CZ 1 ATOM 1932 O OH . TYR A 1 305 ? -44.434 6.335 -35.409 1.00 35.62 ? 305 TYR A OH 1 ATOM 1933 N N . ARG A 1 306 ? -45.949 13.682 -31.373 1.00 44.52 ? 306 ARG A N 1 ATOM 1934 C CA . ARG A 1 306 ? -45.771 14.663 -30.313 1.00 44.63 ? 306 ARG A CA 1 ATOM 1935 C C . ARG A 1 306 ? -45.382 13.927 -29.036 1.00 43.71 ? 306 ARG A C 1 ATOM 1936 O O . ARG A 1 306 ? -45.998 12.924 -28.683 1.00 41.73 ? 306 ARG A O 1 ATOM 1937 C CB . ARG A 1 306 ? -47.052 15.467 -30.091 1.00 45.87 ? 306 ARG A CB 1 ATOM 1938 C CG . ARG A 1 306 ? -47.061 16.229 -28.780 1.00 49.58 ? 306 ARG A CG 1 ATOM 1939 C CD . ARG A 1 306 ? -47.930 17.466 -28.847 1.00 48.02 ? 306 ARG A CD 1 ATOM 1940 N NE . ARG A 1 306 ? -47.607 18.382 -27.759 1.00 48.49 ? 306 ARG A NE 1 ATOM 1941 C CZ . ARG A 1 306 ? -48.150 19.584 -27.607 1.00 51.05 ? 306 ARG A CZ 1 ATOM 1942 N NH1 . ARG A 1 306 ? -49.054 20.023 -28.474 1.00 44.97 ? 306 ARG A NH1 1 ATOM 1943 N NH2 . ARG A 1 306 ? -47.789 20.347 -26.585 1.00 56.52 ? 306 ARG A NH2 1 ATOM 1944 N N . VAL A 1 307 ? -44.355 14.414 -28.349 1.00 44.08 ? 307 VAL A N 1 ATOM 1945 C CA . VAL A 1 307 ? -43.868 13.735 -27.154 1.00 43.40 ? 307 VAL A CA 1 ATOM 1946 C C . VAL A 1 307 ? -44.150 14.541 -25.884 1.00 45.11 ? 307 VAL A C 1 ATOM 1947 O O . VAL A 1 307 ? -43.994 15.761 -25.870 1.00 47.84 ? 307 VAL A O 1 ATOM 1948 C CB . VAL A 1 307 ? -42.361 13.437 -27.262 1.00 48.55 ? 307 VAL A CB 1 ATOM 1949 C CG1 . VAL A 1 307 ? -41.905 12.587 -26.096 1.00 52.23 ? 307 VAL A CG1 1 ATOM 1950 C CG2 . VAL A 1 307 ? -42.056 12.732 -28.573 1.00 44.82 ? 307 VAL A CG2 1 ATOM 1951 N N . TYR A 1 308 ? -44.579 13.855 -24.827 1.00 45.47 ? 308 TYR A N 1 ATOM 1952 C CA . TYR A 1 308 ? -44.812 14.494 -23.535 1.00 46.84 ? 308 TYR A CA 1 ATOM 1953 C C . TYR A 1 308 ? -43.922 13.888 -22.455 1.00 48.27 ? 308 TYR A C 1 ATOM 1954 O O . TYR A 1 308 ? -43.586 12.704 -22.507 1.00 43.53 ? 308 TYR A O 1 ATOM 1955 C CB . TYR A 1 308 ? -46.282 14.375 -23.119 1.00 39.18 ? 308 TYR A CB 1 ATOM 1956 C CG . TYR A 1 308 ? -47.237 15.196 -23.956 1.00 49.99 ? 308 TYR A CG 1 ATOM 1957 C CD1 . TYR A 1 308 ? -47.313 16.574 -23.808 1.00 56.73 ? 308 TYR A CD1 1 ATOM 1958 C CD2 . TYR A 1 308 ? -48.072 14.593 -24.885 1.00 53.07 ? 308 TYR A CD2 1 ATOM 1959 C CE1 . TYR A 1 308 ? -48.188 17.328 -24.569 1.00 59.83 ? 308 TYR A CE1 1 ATOM 1960 C CE2 . TYR A 1 308 ? -48.951 15.339 -25.650 1.00 54.59 ? 308 TYR A CE2 1 ATOM 1961 C CZ . TYR A 1 308 ? -49.005 16.705 -25.487 1.00 58.07 ? 308 TYR A CZ 1 ATOM 1962 O OH . TYR A 1 308 ? -49.878 17.451 -26.245 1.00 59.49 ? 308 TYR A OH 1 ATOM 1963 N N . LEU A 1 309 ? -43.540 14.709 -21.481 1.00 51.53 ? 309 LEU A N 1 ATOM 1964 C CA . LEU A 1 309 ? -42.773 14.242 -20.331 1.00 47.33 ? 309 LEU A CA 1 ATOM 1965 C C . LEU A 1 309 ? -43.545 14.563 -19.059 1.00 48.97 ? 309 LEU A C 1 ATOM 1966 O O . LEU A 1 309 ? -43.805 15.728 -18.760 1.00 52.06 ? 309 LEU A O 1 ATOM 1967 C CB . LEU A 1 309 ? -41.391 14.907 -20.290 1.00 48.57 ? 309 LEU A CB 1 ATOM 1968 C CG . LEU A 1 309 ? -40.219 14.168 -19.629 1.00 51.22 ? 309 LEU A CG 1 ATOM 1969 C CD1 . LEU A 1 309 ? -38.912 14.906 -19.878 1.00 64.73 ? 309 LEU A CD1 1 ATOM 1970 C CD2 . LEU A 1 309 ? -40.420 13.963 -18.134 1.00 49.03 ? 309 LEU A CD2 1 ATOM 1971 N N . LEU A 1 310 ? -43.916 13.527 -18.316 1.00 47.64 ? 310 LEU A N 1 ATOM 1972 C CA . LEU A 1 310 ? -44.550 13.718 -17.018 1.00 48.73 ? 310 LEU A CA 1 ATOM 1973 C C . LEU A 1 310 ? -43.547 13.430 -15.907 1.00 54.03 ? 310 LEU A C 1 ATOM 1974 O O . LEU A 1 310 ? -43.125 12.290 -15.712 1.00 51.03 ? 310 LEU A O 1 ATOM 1975 C CB . LEU A 1 310 ? -45.791 12.832 -16.875 1.00 39.46 ? 310 LEU A CB 1 ATOM 1976 C CG . LEU A 1 310 ? -47.137 13.405 -17.332 1.00 34.91 ? 310 LEU A CG 1 ATOM 1977 C CD1 . LEU A 1 310 ? -46.984 14.754 -18.024 1.00 38.75 ? 310 LEU A CD1 1 ATOM 1978 C CD2 . LEU A 1 310 ? -47.850 12.417 -18.238 1.00 34.80 ? 310 LEU A CD2 1 ATOM 1979 N N . GLY A 1 311 ? -43.162 14.479 -15.189 1.00 56.65 ? 311 GLY A N 1 ATOM 1980 C CA . GLY A 1 311 ? -42.171 14.373 -14.136 1.00 64.97 ? 311 GLY A CA 1 ATOM 1981 C C . GLY A 1 311 ? -41.693 15.748 -13.714 1.00 81.99 ? 311 GLY A C 1 ATOM 1982 O O . GLY A 1 311 ? -41.951 16.738 -14.399 1.00 81.12 ? 311 GLY A O 1 ATOM 1983 N N . ARG A 1 312 ? -41.003 15.813 -12.580 1.00 88.33 ? 312 ARG A N 1 ATOM 1984 C CA . ARG A 1 312 ? -40.534 17.083 -12.035 1.00 93.15 ? 312 ARG A CA 1 ATOM 1985 C C . ARG A 1 312 ? -39.086 17.388 -12.398 1.00 102.40 ? 312 ARG A C 1 ATOM 1986 O O . ARG A 1 312 ? -38.540 18.413 -11.990 1.00 113.57 ? 312 ARG A O 1 ATOM 1987 C CB . ARG A 1 312 ? -40.691 17.094 -10.515 1.00 85.41 ? 312 ARG A CB 1 ATOM 1988 C CG . ARG A 1 312 ? -41.803 17.991 -10.015 1.00 77.13 ? 312 ARG A CG 1 ATOM 1989 C CD . ARG A 1 312 ? -41.734 18.135 -8.509 1.00 81.14 ? 312 ARG A CD 1 ATOM 1990 N NE . ARG A 1 312 ? -42.563 19.232 -8.023 1.00 83.09 ? 312 ARG A NE 1 ATOM 1991 C CZ . ARG A 1 312 ? -42.189 20.506 -8.029 1.00 84.34 ? 312 ARG A CZ 1 ATOM 1992 N NH1 . ARG A 1 312 ? -40.998 20.849 -8.503 1.00 83.36 ? 312 ARG A NH1 1 ATOM 1993 N NH2 . ARG A 1 312 ? -43.007 21.439 -7.565 1.00 83.04 ? 312 ARG A NH2 1 ATOM 1994 N N . GLY A 1 313 ? -38.470 16.498 -13.166 1.00 100.83 ? 313 GLY A N 1 ATOM 1995 C CA . GLY A 1 313 ? -37.046 16.578 -13.428 1.00 116.17 ? 313 GLY A CA 1 ATOM 1996 C C . GLY A 1 313 ? -36.580 17.686 -14.354 1.00 131.01 ? 313 GLY A C 1 ATOM 1997 O O . GLY A 1 313 ? -35.378 17.892 -14.492 1.00 135.14 ? 313 GLY A O 1 ATOM 1998 N N . LEU A 1 314 ? -37.517 18.410 -14.964 1.00 126.82 ? 314 LEU A N 1 ATOM 1999 C CA . LEU A 1 314 ? -37.202 19.391 -16.010 1.00 126.02 ? 314 LEU A CA 1 ATOM 2000 C C . LEU A 1 314 ? -36.068 20.354 -15.650 1.00 137.53 ? 314 LEU A C 1 ATOM 2001 O O . LEU A 1 314 ? -35.165 20.597 -16.452 1.00 137.11 ? 314 LEU A O 1 ATOM 2002 C CB . LEU A 1 314 ? -38.449 20.191 -16.386 1.00 109.04 ? 314 LEU A CB 1 ATOM 2003 C CG . LEU A 1 314 ? -39.699 19.412 -16.792 1.00 96.24 ? 314 LEU A CG 1 ATOM 2004 C CD1 . LEU A 1 314 ? -40.695 20.365 -17.421 1.00 85.58 ? 314 LEU A CD1 1 ATOM 2005 C CD2 . LEU A 1 314 ? -39.361 18.276 -17.742 1.00 89.38 ? 314 LEU A CD2 1 ATOM 2006 N N . ASP A 1 315 ? -36.131 20.903 -14.442 1.00 145.12 ? 315 ASP A N 1 ATOM 2007 C CA . ASP A 1 315 ? -35.070 21.757 -13.913 1.00 142.54 ? 315 ASP A CA 1 ATOM 2008 C C . ASP A 1 315 ? -34.605 21.275 -12.539 1.00 139.00 ? 315 ASP A C 1 ATOM 2009 O O . ASP A 1 315 ? -33.427 20.970 -12.349 1.00 135.73 ? 315 ASP A O 1 ATOM 2010 C CB . ASP A 1 315 ? -35.479 23.235 -13.880 1.00 141.53 ? 315 ASP A CB 1 ATOM 2011 C CG . ASP A 1 315 ? -36.892 23.443 -13.379 1.00 143.34 ? 315 ASP A CG 1 ATOM 2012 O OD1 . ASP A 1 315 ? -37.545 22.449 -13.001 1.00 145.61 ? 315 ASP A OD1 1 ATOM 2013 O OD2 . ASP A 1 315 ? -37.348 24.606 -13.356 1.00 144.40 ? 315 ASP A OD2 1 ATOM 2014 N N . MET A 1 316 ? -35.544 21.228 -11.594 1.00 143.90 ? 316 MET A N 1 ATOM 2015 C CA . MET A 1 316 ? -35.278 20.915 -10.188 1.00 143.52 ? 316 MET A CA 1 ATOM 2016 C C . MET A 1 316 ? -34.367 19.706 -9.976 1.00 145.28 ? 316 MET A C 1 ATOM 2017 O O . MET A 1 316 ? -33.444 19.751 -9.160 1.00 153.31 ? 316 MET A O 1 ATOM 2018 C CB . MET A 1 316 ? -36.598 20.644 -9.453 1.00 132.66 ? 316 MET A CB 1 ATOM 2019 C CG . MET A 1 316 ? -37.825 21.325 -10.048 1.00 133.93 ? 316 MET A CG 1 ATOM 2020 S SD . MET A 1 316 ? -38.049 23.021 -9.484 1.00 142.18 ? 316 MET A SD 1 ATOM 2021 C CE . MET A 1 316 ? -38.297 22.756 -7.730 1.00 112.87 ? 316 MET A CE 1 ATOM 2022 N N . ASN A 1 317 ? -34.627 18.632 -10.714 1.00 137.88 ? 317 ASN A N 1 ATOM 2023 C CA . ASN A 1 317 ? -33.945 17.357 -10.490 1.00 141.29 ? 317 ASN A CA 1 ATOM 2024 C C . ASN A 1 317 ? -32.804 17.015 -11.456 1.00 143.46 ? 317 ASN A C 1 ATOM 2025 O O . ASN A 1 317 ? -31.665 16.831 -11.022 1.00 137.74 ? 317 ASN A O 1 ATOM 2026 C CB . ASN A 1 317 ? -34.955 16.211 -10.398 1.00 130.45 ? 317 ASN A CB 1 ATOM 2027 C CG . ASN A 1 317 ? -35.634 16.145 -9.041 1.00 122.66 ? 317 ASN A CG 1 ATOM 2028 O OD1 . ASN A 1 317 ? -36.489 16.970 -8.719 1.00 113.38 ? 317 ASN A OD1 1 ATOM 2029 N ND2 . ASN A 1 317 ? -35.254 15.157 -8.237 1.00 113.05 ? 317 ASN A ND2 1 ATOM 2030 N N . PHE A 1 318 ? -33.118 16.906 -12.749 1.00 141.94 ? 318 PHE A N 1 ATOM 2031 C CA . PHE A 1 318 ? -32.143 16.490 -13.766 1.00 138.18 ? 318 PHE A CA 1 ATOM 2032 C C . PHE A 1 318 ? -30.839 17.276 -13.703 1.00 136.24 ? 318 PHE A C 1 ATOM 2033 O O . PHE A 1 318 ? -30.836 18.484 -13.476 1.00 142.72 ? 318 PHE A O 1 ATOM 2034 C CB . PHE A 1 318 ? -32.733 16.605 -15.175 1.00 136.32 ? 318 PHE A CB 1 ATOM 2035 C CG . PHE A 1 318 ? -33.299 15.319 -15.707 1.00 129.39 ? 318 PHE A CG 1 ATOM 2036 C CD1 . PHE A 1 318 ? -32.862 14.807 -16.918 1.00 113.83 ? 318 PHE A CD1 1 ATOM 2037 C CD2 . PHE A 1 318 ? -34.263 14.621 -14.997 1.00 119.87 ? 318 PHE A CD2 1 ATOM 2038 C CE1 . PHE A 1 318 ? -33.378 13.629 -17.415 1.00 89.74 ? 318 PHE A CE1 1 ATOM 2039 C CE2 . PHE A 1 318 ? -34.783 13.438 -15.489 1.00 105.79 ? 318 PHE A CE2 1 ATOM 2040 C CZ . PHE A 1 318 ? -34.339 12.942 -16.699 1.00 93.56 ? 318 PHE A CZ 1 ATOM 2041 N N . SER A 1 319 ? -29.731 16.567 -13.887 1.00 127.83 ? 319 SER A N 1 ATOM 2042 C CA . SER A 1 319 ? -28.406 17.164 -13.776 1.00 133.27 ? 319 SER A CA 1 ATOM 2043 C C . SER A 1 319 ? -28.128 18.196 -14.866 1.00 136.63 ? 319 SER A C 1 ATOM 2044 O O . SER A 1 319 ? -27.414 19.172 -14.636 1.00 143.90 ? 319 SER A O 1 ATOM 2045 C CB . SER A 1 319 ? -27.341 16.081 -13.796 1.00 131.58 ? 319 SER A CB 1 ATOM 2046 N N . LYS A 1 320 ? -28.701 17.982 -16.045 1.00 133.11 ? 320 LYS A N 1 ATOM 2047 C CA . LYS A 1 320 ? -28.343 18.772 -17.219 1.00 130.92 ? 320 LYS A CA 1 ATOM 2048 C C . LYS A 1 320 ? -29.544 19.342 -17.972 1.00 130.83 ? 320 LYS A C 1 ATOM 2049 O O . LYS A 1 320 ? -30.684 19.267 -17.511 1.00 127.80 ? 320 LYS A O 1 ATOM 2050 C CB . LYS A 1 320 ? -27.469 17.950 -18.162 1.00 119.96 ? 320 LYS A CB 1 ATOM 2051 N N . HIS A 1 321 ? -29.261 19.907 -19.142 1.00 130.99 ? 321 HIS A N 1 ATOM 2052 C CA . HIS A 1 321 ? -30.274 20.480 -20.024 1.00 125.56 ? 321 HIS A CA 1 ATOM 2053 C C . HIS A 1 321 ? -30.833 19.378 -20.917 1.00 119.16 ? 321 HIS A C 1 ATOM 2054 O O . HIS A 1 321 ? -31.540 19.638 -21.889 1.00 115.91 ? 321 HIS A O 1 ATOM 2055 C CB . HIS A 1 321 ? -29.707 21.630 -20.861 1.00 120.72 ? 321 HIS A CB 1 ATOM 2056 C CG . HIS A 1 321 ? -30.624 22.811 -20.962 1.00 127.65 ? 321 HIS A CG 1 ATOM 2057 N ND1 . HIS A 1 321 ? -31.879 22.735 -21.529 1.00 125.15 ? 321 HIS A ND1 1 ATOM 2058 C CD2 . HIS A 1 321 ? -30.470 24.096 -20.565 1.00 129.10 ? 321 HIS A CD2 1 ATOM 2059 C CE1 . HIS A 1 321 ? -32.457 23.922 -21.477 1.00 121.28 ? 321 HIS A CE1 1 ATOM 2060 N NE2 . HIS A 1 321 ? -31.623 24.766 -20.897 1.00 124.18 ? 321 HIS A NE2 1 ATOM 2061 N N . ALA A 1 322 ? -30.483 18.142 -20.570 1.00 120.30 ? 322 ALA A N 1 ATOM 2062 C CA . ALA A 1 322 ? -30.866 16.950 -21.316 1.00 111.49 ? 322 ALA A CA 1 ATOM 2063 C C . ALA A 1 322 ? -32.316 16.560 -21.028 1.00 115.52 ? 322 ALA A C 1 ATOM 2064 O O . ALA A 1 322 ? -32.787 15.514 -21.475 1.00 111.52 ? 322 ALA A O 1 ATOM 2065 C CB . ALA A 1 322 ? -29.929 15.796 -20.983 1.00 102.52 ? 322 ALA A CB 1 ATOM 2066 N N . THR A 1 323 ? -33.004 17.378 -20.237 1.00 113.97 ? 323 THR A N 1 ATOM 2067 C CA . THR A 1 323 ? -34.451 17.261 -20.085 1.00 98.87 ? 323 THR A CA 1 ATOM 2068 C C . THR A 1 323 ? -35.139 17.270 -21.452 1.00 83.54 ? 323 THR A C 1 ATOM 2069 O O . THR A 1 323 ? -36.193 16.660 -21.631 1.00 66.15 ? 323 THR A O 1 ATOM 2070 C CB . THR A 1 323 ? -34.984 18.386 -19.215 1.00 98.70 ? 323 THR A CB 1 ATOM 2071 N N . VAL A 1 324 ? -34.534 17.969 -22.409 1.00 89.44 ? 324 VAL A N 1 ATOM 2072 C CA . VAL A 1 324 ? -35.019 17.983 -23.785 1.00 84.09 ? 324 VAL A CA 1 ATOM 2073 C C . VAL A 1 324 ? -34.442 16.824 -24.598 1.00 82.56 ? 324 VAL A C 1 ATOM 2074 O O . VAL A 1 324 ? -34.906 16.545 -25.703 1.00 82.39 ? 324 VAL A O 1 ATOM 2075 C CB . VAL A 1 324 ? -34.663 19.302 -24.505 1.00 80.42 ? 324 VAL A CB 1 ATOM 2076 C CG1 . VAL A 1 324 ? -35.107 20.496 -23.679 1.00 86.25 ? 324 VAL A CG1 1 ATOM 2077 C CG2 . VAL A 1 324 ? -33.170 19.376 -24.792 1.00 84.19 ? 324 VAL A CG2 1 ATOM 2078 N N . ASP A 1 325 ? -33.430 16.157 -24.049 1.00 85.50 ? 325 ASP A N 1 ATOM 2079 C CA . ASP A 1 325 ? -32.766 15.054 -24.741 1.00 85.16 ? 325 ASP A CA 1 ATOM 2080 C C . ASP A 1 325 ? -33.650 13.808 -24.752 1.00 75.21 ? 325 ASP A C 1 ATOM 2081 O O . ASP A 1 325 ? -33.782 13.150 -25.781 1.00 76.40 ? 325 ASP A O 1 ATOM 2082 C CB . ASP A 1 325 ? -31.409 14.746 -24.095 1.00 87.78 ? 325 ASP A CB 1 ATOM 2083 C CG . ASP A 1 325 ? -30.288 14.597 -25.111 1.00 98.14 ? 325 ASP A CG 1 ATOM 2084 O OD1 . ASP A 1 325 ? -30.520 14.853 -26.313 1.00 94.14 ? 325 ASP A OD1 1 ATOM 2085 O OD2 . ASP A 1 325 ? -29.164 14.237 -24.701 1.00 96.69 ? 325 ASP A OD2 1 ATOM 2086 N N . ILE A 1 326 ? -34.260 13.497 -23.609 1.00 65.02 ? 326 ILE A N 1 ATOM 2087 C CA . ILE A 1 326 ? -35.151 12.342 -23.499 1.00 58.77 ? 326 ILE A CA 1 ATOM 2088 C C . ILE A 1 326 ? -36.433 12.537 -24.309 1.00 61.13 ? 326 ILE A C 1 ATOM 2089 O O . ILE A 1 326 ? -36.935 11.598 -24.926 1.00 56.94 ? 326 ILE A O 1 ATOM 2090 C CB . ILE A 1 326 ? -35.516 12.034 -22.031 1.00 53.94 ? 326 ILE A CB 1 ATOM 2091 C CG1 . ILE A 1 326 ? -34.254 11.946 -21.173 1.00 68.14 ? 326 ILE A CG1 1 ATOM 2092 C CG2 . ILE A 1 326 ? -36.314 10.741 -21.934 1.00 45.71 ? 326 ILE A CG2 1 ATOM 2093 C CD1 . ILE A 1 326 ? -34.487 11.335 -19.808 1.00 71.15 ? 326 ILE A CD1 1 ATOM 2094 N N . CYS A 1 327 ? -36.956 13.760 -24.309 1.00 64.92 ? 327 CYS A N 1 ATOM 2095 C CA . CYS A 1 327 ? -38.157 14.077 -25.079 1.00 59.86 ? 327 CYS A CA 1 ATOM 2096 C C . CYS A 1 327 ? -37.953 13.889 -26.579 1.00 58.78 ? 327 CYS A C 1 ATOM 2097 O O . CYS A 1 327 ? -38.915 13.720 -27.325 1.00 61.16 ? 327 CYS A O 1 ATOM 2098 C CB . CYS A 1 327 ? -38.623 15.507 -24.799 1.00 64.28 ? 327 CYS A CB 1 ATOM 2099 S SG . CYS A 1 327 ? -39.771 15.672 -23.414 1.00 67.47 ? 327 CYS A SG 1 ATOM 2100 N N . ALA A 1 328 ? -36.699 13.921 -27.017 1.00 61.50 ? 328 ALA A N 1 ATOM 2101 C CA . ALA A 1 328 ? -36.387 13.750 -28.430 1.00 59.12 ? 328 ALA A CA 1 ATOM 2102 C C . ALA A 1 328 ? -36.099 12.292 -28.801 1.00 56.10 ? 328 ALA A C 1 ATOM 2103 O O . ALA A 1 328 ? -35.912 11.980 -29.974 1.00 56.59 ? 328 ALA A O 1 ATOM 2104 C CB . ALA A 1 328 ? -35.217 14.644 -28.827 1.00 62.47 ? 328 ALA A CB 1 ATOM 2105 N N . TYR A 1 329 ? -36.070 11.409 -27.803 1.00 54.70 ? 329 TYR A N 1 ATOM 2106 C CA . TYR A 1 329 ? -35.789 9.983 -28.027 1.00 51.58 ? 329 TYR A CA 1 ATOM 2107 C C . TYR A 1 329 ? -36.643 9.296 -29.113 1.00 46.55 ? 329 TYR A C 1 ATOM 2108 O O . TYR A 1 329 ? -36.090 8.683 -30.027 1.00 45.61 ? 329 TYR A O 1 ATOM 2109 C CB . TYR A 1 329 ? -35.862 9.179 -26.714 1.00 57.71 ? 329 TYR A CB 1 ATOM 2110 C CG . TYR A 1 329 ? -34.607 9.198 -25.863 1.00 59.20 ? 329 TYR A CG 1 ATOM 2111 C CD1 . TYR A 1 329 ? -33.648 10.188 -26.016 1.00 60.06 ? 329 TYR A CD1 1 ATOM 2112 C CD2 . TYR A 1 329 ? -34.381 8.212 -24.911 1.00 51.78 ? 329 TYR A CD2 1 ATOM 2113 C CE1 . TYR A 1 329 ? -32.505 10.200 -25.241 1.00 60.15 ? 329 TYR A CE1 1 ATOM 2114 C CE2 . TYR A 1 329 ? -33.241 8.217 -24.132 1.00 46.33 ? 329 TYR A CE2 1 ATOM 2115 C CZ . TYR A 1 329 ? -32.306 9.212 -24.302 1.00 53.10 ? 329 TYR A CZ 1 ATOM 2116 O OH . TYR A 1 329 ? -31.168 9.225 -23.532 1.00 58.59 ? 329 TYR A OH 1 ATOM 2117 N N . PRO A 1 330 ? -37.985 9.380 -29.013 1.00 48.84 ? 330 PRO A N 1 ATOM 2118 C CA . PRO A 1 330 ? -38.807 8.641 -29.981 1.00 48.47 ? 330 PRO A CA 1 ATOM 2119 C C . PRO A 1 330 ? -38.745 9.224 -31.391 1.00 49.25 ? 330 PRO A C 1 ATOM 2120 O O . PRO A 1 330 ? -38.968 8.502 -32.363 1.00 43.40 ? 330 PRO A O 1 ATOM 2121 C CB . PRO A 1 330 ? -40.230 8.791 -29.419 1.00 49.62 ? 330 PRO A CB 1 ATOM 2122 C CG . PRO A 1 330 ? -40.059 9.288 -28.015 1.00 47.72 ? 330 PRO A CG 1 ATOM 2123 C CD . PRO A 1 330 ? -38.828 10.116 -28.056 1.00 52.68 ? 330 PRO A CD 1 ATOM 2124 N N . GLU A 1 331 ? -38.452 10.517 -31.494 1.00 49.82 ? 331 GLU A N 1 ATOM 2125 C CA . GLU A 1 331 ? -38.438 11.197 -32.786 1.00 51.27 ? 331 GLU A CA 1 ATOM 2126 C C . GLU A 1 331 ? -37.109 11.049 -33.519 1.00 54.69 ? 331 GLU A C 1 ATOM 2127 O O . GLU A 1 331 ? -36.954 11.542 -34.636 1.00 56.02 ? 331 GLU A O 1 ATOM 2128 C CB . GLU A 1 331 ? -38.770 12.681 -32.619 1.00 56.04 ? 331 GLU A CB 1 ATOM 2129 C CG . GLU A 1 331 ? -40.184 12.951 -32.142 1.00 57.20 ? 331 GLU A CG 1 ATOM 2130 C CD . GLU A 1 331 ? -40.537 14.425 -32.169 1.00 57.87 ? 331 GLU A CD 1 ATOM 2131 O OE1 . GLU A 1 331 ? -40.133 15.156 -31.239 1.00 57.56 ? 331 GLU A OE1 1 ATOM 2132 O OE2 . GLU A 1 331 ? -41.220 14.852 -33.122 1.00 47.97 ? 331 GLU A OE2 1 ATOM 2133 N N . GLU A 1 332 ? -36.150 10.383 -32.883 1.00 52.78 ? 332 GLU A N 1 ATOM 2134 C CA . GLU A 1 332 ? -34.844 10.159 -33.491 1.00 45.34 ? 332 GLU A CA 1 ATOM 2135 C C . GLU A 1 332 ? -34.887 9.078 -34.571 1.00 43.27 ? 332 GLU A C 1 ATOM 2136 O O . GLU A 1 332 ? -34.357 9.271 -35.664 1.00 48.13 ? 332 GLU A O 1 ATOM 2137 C CB . GLU A 1 332 ? -33.794 9.820 -32.425 1.00 47.44 ? 332 GLU A CB 1 ATOM 2138 C CG . GLU A 1 332 ? -33.334 11.021 -31.603 1.00 52.69 ? 332 GLU A CG 1 ATOM 2139 C CD . GLU A 1 332 ? -32.433 10.638 -30.440 1.00 52.57 ? 332 GLU A CD 1 ATOM 2140 O OE1 . GLU A 1 332 ? -31.864 11.550 -29.802 1.00 50.88 ? 332 GLU A OE1 1 ATOM 2141 O OE2 . GLU A 1 332 ? -32.299 9.429 -30.158 1.00 53.63 ? 332 GLU A OE2 1 ATOM 2142 N N . SER A 1 333 ? -35.506 7.941 -34.264 1.00 37.62 ? 333 SER A N 1 ATOM 2143 C CA . SER A 1 333 ? -35.575 6.843 -35.226 1.00 40.06 ? 333 SER A CA 1 ATOM 2144 C C . SER A 1 333 ? -36.726 5.865 -35.001 1.00 43.19 ? 333 SER A C 1 ATOM 2145 O O . SER A 1 333 ? -37.237 5.741 -33.888 1.00 47.80 ? 333 SER A O 1 ATOM 2146 C CB . SER A 1 333 ? -34.264 6.064 -35.215 1.00 42.45 ? 333 SER A CB 1 ATOM 2147 O OG . SER A 1 333 ? -34.320 4.991 -36.138 1.00 43.77 ? 333 SER A OG 1 ATOM 2148 N N . LEU A 1 334 ? -37.127 5.176 -36.068 1.00 43.13 ? 334 LEU A N 1 ATOM 2149 C CA . LEU A 1 334 ? -38.023 4.026 -35.962 1.00 40.38 ? 334 LEU A CA 1 ATOM 2150 C C . LEU A 1 334 ? -37.225 2.727 -35.990 1.00 39.96 ? 334 LEU A C 1 ATOM 2151 O O . LEU A 1 334 ? -37.784 1.635 -35.871 1.00 40.23 ? 334 LEU A O 1 ATOM 2152 C CB . LEU A 1 334 ? -39.069 4.026 -37.080 1.00 36.82 ? 334 LEU A CB 1 ATOM 2153 C CG . LEU A 1 334 ? -40.213 5.034 -36.965 1.00 42.97 ? 334 LEU A CG 1 ATOM 2154 C CD1 . LEU A 1 334 ? -41.376 4.644 -37.865 1.00 38.55 ? 334 LEU A CD1 1 ATOM 2155 C CD2 . LEU A 1 334 ? -40.667 5.139 -35.525 1.00 46.78 ? 334 LEU A CD2 1 ATOM 2156 N N . ASP A 1 335 ? -35.912 2.856 -36.152 1.00 40.84 ? 335 ASP A N 1 ATOM 2157 C CA . ASP A 1 335 ? -35.028 1.701 -36.171 1.00 43.10 ? 335 ASP A CA 1 ATOM 2158 C C . ASP A 1 335 ? -34.692 1.354 -34.729 1.00 40.29 ? 335 ASP A C 1 ATOM 2159 O O . ASP A 1 335 ? -34.107 2.161 -34.005 1.00 41.62 ? 335 ASP A O 1 ATOM 2160 C CB . ASP A 1 335 ? -33.753 2.019 -36.960 1.00 45.53 ? 335 ASP A CB 1 ATOM 2161 C CG . ASP A 1 335 ? -33.021 0.774 -37.427 1.00 46.28 ? 335 ASP A CG 1 ATOM 2162 O OD1 . ASP A 1 335 ? -33.256 -0.315 -36.863 1.00 45.22 ? 335 ASP A OD1 1 ATOM 2163 O OD2 . ASP A 1 335 ? -32.200 0.892 -38.361 1.00 48.86 ? 335 ASP A OD2 1 ATOM 2164 N N . TYR A 1 336 ? -35.073 0.151 -34.314 1.00 35.11 ? 336 TYR A N 1 ATOM 2165 C CA . TYR A 1 336 ? -34.904 -0.265 -32.929 1.00 34.44 ? 336 TYR A CA 1 ATOM 2166 C C . TYR A 1 336 ? -33.433 -0.443 -32.578 1.00 35.11 ? 336 TYR A C 1 ATOM 2167 O O . TYR A 1 336 ? -33.049 -0.364 -31.411 1.00 37.98 ? 336 TYR A O 1 ATOM 2168 C CB . TYR A 1 336 ? -35.676 -1.557 -32.665 1.00 31.07 ? 336 TYR A CB 1 ATOM 2169 C CG . TYR A 1 336 ? -34.996 -2.810 -33.167 1.00 30.23 ? 336 TYR A CG 1 ATOM 2170 C CD1 . TYR A 1 336 ? -34.402 -3.697 -32.284 1.00 32.39 ? 336 TYR A CD1 1 ATOM 2171 C CD2 . TYR A 1 336 ? -34.954 -3.109 -34.520 1.00 38.71 ? 336 TYR A CD2 1 ATOM 2172 C CE1 . TYR A 1 336 ? -33.783 -4.845 -32.732 1.00 34.71 ? 336 TYR A CE1 1 ATOM 2173 C CE2 . TYR A 1 336 ? -34.335 -4.256 -34.979 1.00 44.02 ? 336 TYR A CE2 1 ATOM 2174 C CZ . TYR A 1 336 ? -33.752 -5.120 -34.079 1.00 39.29 ? 336 TYR A CZ 1 ATOM 2175 O OH . TYR A 1 336 ? -33.136 -6.264 -34.530 1.00 41.37 ? 336 TYR A OH 1 ATOM 2176 N N . ARG A 1 337 ? -32.617 -0.679 -33.599 1.00 35.67 ? 337 ARG A N 1 ATOM 2177 C CA . ARG A 1 337 ? -31.177 -0.809 -33.420 1.00 42.15 ? 337 ARG A CA 1 ATOM 2178 C C . ARG A 1 337 ? -30.553 0.522 -32.999 1.00 40.46 ? 337 ARG A C 1 ATOM 2179 O O . ARG A 1 337 ? -29.547 0.543 -32.293 1.00 42.23 ? 337 ARG A O 1 ATOM 2180 C CB . ARG A 1 337 ? -30.521 -1.306 -34.711 1.00 44.52 ? 337 ARG A CB 1 ATOM 2181 C CG . ARG A 1 337 ? -31.071 -2.617 -35.249 1.00 41.77 ? 337 ARG A CG 1 ATOM 2182 C CD . ARG A 1 337 ? -30.585 -2.841 -36.669 1.00 40.46 ? 337 ARG A CD 1 ATOM 2183 N NE . ARG A 1 337 ? -30.824 -1.663 -37.496 1.00 43.57 ? 337 ARG A NE 1 ATOM 2184 C CZ . ARG A 1 337 ? -30.382 -1.520 -38.740 1.00 47.77 ? 337 ARG A CZ 1 ATOM 2185 N NH1 . ARG A 1 337 ? -29.673 -2.486 -39.304 1.00 51.97 ? 337 ARG A NH1 1 ATOM 2186 N NH2 . ARG A 1 337 ? -30.648 -0.412 -39.417 1.00 47.31 ? 337 ARG A NH2 1 ATOM 2187 N N . TYR A 1 338 ? -31.148 1.627 -33.443 1.00 35.59 ? 338 TYR A N 1 ATOM 2188 C CA . TYR A 1 338 ? -30.651 2.959 -33.106 1.00 33.08 ? 338 TYR A CA 1 ATOM 2189 C C . TYR A 1 338 ? -30.716 3.195 -31.605 1.00 37.68 ? 338 TYR A C 1 ATOM 2190 O O . TYR A 1 338 ? -29.766 3.692 -31.003 1.00 43.09 ? 338 TYR A O 1 ATOM 2191 C CB . TYR A 1 338 ? -31.457 4.037 -33.837 1.00 32.88 ? 338 TYR A CB 1 ATOM 2192 C CG . TYR A 1 338 ? -30.979 5.454 -33.589 1.00 31.01 ? 338 TYR A CG 1 ATOM 2193 C CD1 . TYR A 1 338 ? -30.108 6.074 -34.470 1.00 37.48 ? 338 TYR A CD1 1 ATOM 2194 C CD2 . TYR A 1 338 ? -31.408 6.173 -32.482 1.00 33.64 ? 338 TYR A CD2 1 ATOM 2195 C CE1 . TYR A 1 338 ? -29.672 7.366 -34.252 1.00 42.91 ? 338 TYR A CE1 1 ATOM 2196 C CE2 . TYR A 1 338 ? -30.975 7.462 -32.256 1.00 36.02 ? 338 TYR A CE2 1 ATOM 2197 C CZ . TYR A 1 338 ? -30.109 8.054 -33.143 1.00 37.39 ? 338 TYR A CZ 1 ATOM 2198 O OH . TYR A 1 338 ? -29.679 9.340 -32.919 1.00 43.79 ? 338 TYR A OH 1 ATOM 2199 N N . HIS A 1 339 ? -31.846 2.843 -31.004 1.00 36.53 ? 339 HIS A N 1 ATOM 2200 C CA . HIS A 1 339 ? -32.053 3.077 -29.582 1.00 34.92 ? 339 HIS A CA 1 ATOM 2201 C C . HIS A 1 339 ? -31.294 2.067 -28.726 1.00 35.46 ? 339 HIS A C 1 ATOM 2202 O O . HIS A 1 339 ? -30.818 2.397 -27.642 1.00 41.13 ? 339 HIS A O 1 ATOM 2203 C CB . HIS A 1 339 ? -33.548 3.062 -29.251 1.00 31.57 ? 339 HIS A CB 1 ATOM 2204 C CG . HIS A 1 339 ? -34.321 4.157 -29.917 1.00 29.69 ? 339 HIS A CG 1 ATOM 2205 N ND1 . HIS A 1 339 ? -35.559 3.953 -30.487 1.00 30.34 ? 339 HIS A ND1 1 ATOM 2206 C CD2 . HIS A 1 339 ? -34.032 5.466 -30.102 1.00 32.47 ? 339 HIS A CD2 1 ATOM 2207 C CE1 . HIS A 1 339 ? -35.998 5.090 -30.996 1.00 35.50 ? 339 HIS A CE1 1 ATOM 2208 N NE2 . HIS A 1 339 ? -35.091 6.024 -30.775 1.00 35.33 ? 339 HIS A NE2 1 ATOM 2209 N N . LEU A 1 340 ? -31.174 0.840 -29.217 1.00 31.99 ? 340 LEU A N 1 ATOM 2210 C CA . LEU A 1 340 ? -30.450 -0.194 -28.487 1.00 30.87 ? 340 LEU A CA 1 ATOM 2211 C C . LEU A 1 340 ? -28.936 0.008 -28.582 1.00 36.89 ? 340 LEU A C 1 ATOM 2212 O O . LEU A 1 340 ? -28.182 -0.501 -27.753 1.00 43.03 ? 340 LEU A O 1 ATOM 2213 C CB . LEU A 1 340 ? -30.871 -1.588 -28.959 1.00 29.15 ? 340 LEU A CB 1 ATOM 2214 C CG . LEU A 1 340 ? -32.340 -1.907 -28.662 1.00 35.58 ? 340 LEU A CG 1 ATOM 2215 C CD1 . LEU A 1 340 ? -32.743 -3.286 -29.155 1.00 37.73 ? 340 LEU A CD1 1 ATOM 2216 C CD2 . LEU A 1 340 ? -32.620 -1.776 -27.177 1.00 38.55 ? 340 LEU A CD2 1 ATOM 2217 N N . SER A 1 341 ? -28.502 0.756 -29.594 1.00 37.37 ? 341 SER A N 1 ATOM 2218 C CA . SER A 1 341 ? -27.103 1.152 -29.722 1.00 37.71 ? 341 SER A CA 1 ATOM 2219 C C . SER A 1 341 ? -26.768 2.217 -28.686 1.00 35.92 ? 341 SER A C 1 ATOM 2220 O O . SER A 1 341 ? -25.784 2.103 -27.957 1.00 37.77 ? 341 SER A O 1 ATOM 2221 C CB . SER A 1 341 ? -26.822 1.682 -31.133 1.00 43.06 ? 341 SER A CB 1 ATOM 2222 O OG . SER A 1 341 ? -25.484 2.135 -31.265 1.00 50.41 ? 341 SER A OG 1 ATOM 2223 N N . MET A 1 342 ? -27.605 3.248 -28.617 1.00 35.92 ? 342 MET A N 1 ATOM 2224 C CA . MET A 1 342 ? -27.418 4.323 -27.650 1.00 43.55 ? 342 MET A CA 1 ATOM 2225 C C . MET A 1 342 ? -27.628 3.824 -26.223 1.00 49.00 ? 342 MET A C 1 ATOM 2226 O O . MET A 1 342 ? -27.189 4.458 -25.262 1.00 51.97 ? 342 MET A O 1 ATOM 2227 C CB . MET A 1 342 ? -28.364 5.488 -27.944 1.00 44.60 ? 342 MET A CB 1 ATOM 2228 C CG . MET A 1 342 ? -28.106 6.175 -29.267 1.00 44.80 ? 342 MET A CG 1 ATOM 2229 S SD . MET A 1 342 ? -26.388 6.681 -29.422 1.00 71.72 ? 342 MET A SD 1 ATOM 2230 C CE . MET A 1 342 ? -26.226 7.793 -28.026 1.00 66.30 ? 342 MET A CE 1 ATOM 2231 N N . ALA A 1 343 ? -28.308 2.690 -26.091 1.00 47.84 ? 343 ALA A N 1 ATOM 2232 C CA . ALA A 1 343 ? -28.478 2.048 -24.795 1.00 42.03 ? 343 ALA A CA 1 ATOM 2233 C C . ALA A 1 343 ? -27.219 1.267 -24.423 1.00 44.82 ? 343 ALA A C 1 ATOM 2234 O O . ALA A 1 343 ? -26.777 1.300 -23.276 1.00 51.95 ? 343 ALA A O 1 ATOM 2235 C CB . ALA A 1 343 ? -29.695 1.137 -24.810 1.00 38.90 ? 343 ALA A CB 1 ATOM 2236 N N . HIS A 1 344 ? -26.644 0.573 -25.402 1.00 41.00 ? 344 HIS A N 1 ATOM 2237 C CA . HIS A 1 344 ? -25.435 -0.222 -25.190 1.00 41.23 ? 344 HIS A CA 1 ATOM 2238 C C . HIS A 1 344 ? -24.199 0.633 -24.904 1.00 43.54 ? 344 HIS A C 1 ATOM 2239 O O . HIS A 1 344 ? -23.369 0.270 -24.069 1.00 43.31 ? 344 HIS A O 1 ATOM 2240 C CB . HIS A 1 344 ? -25.165 -1.122 -26.399 1.00 41.57 ? 344 HIS A CB 1 ATOM 2241 C CG . HIS A 1 344 ? -25.875 -2.440 -26.354 1.00 37.40 ? 344 HIS A CG 1 ATOM 2242 N ND1 . HIS A 1 344 ? -25.764 -3.376 -27.360 1.00 35.57 ? 344 HIS A ND1 1 ATOM 2243 C CD2 . HIS A 1 344 ? -26.698 -2.984 -25.426 1.00 36.46 ? 344 HIS A CD2 1 ATOM 2244 C CE1 . HIS A 1 344 ? -26.489 -4.436 -27.056 1.00 37.23 ? 344 HIS A CE1 1 ATOM 2245 N NE2 . HIS A 1 344 ? -27.066 -4.224 -25.887 1.00 36.90 ? 344 HIS A NE2 1 ATOM 2246 N N . THR A 1 345 ? -24.069 1.752 -25.612 1.00 45.54 ? 345 THR A N 1 ATOM 2247 C CA . THR A 1 345 ? -22.936 2.655 -25.425 1.00 49.39 ? 345 THR A CA 1 ATOM 2248 C C . THR A 1 345 ? -22.898 3.197 -24.000 1.00 52.16 ? 345 THR A C 1 ATOM 2249 O O . THR A 1 345 ? -21.895 3.063 -23.300 1.00 60.41 ? 345 THR A O 1 ATOM 2250 C CB . THR A 1 345 ? -22.974 3.833 -26.427 1.00 54.39 ? 345 THR A CB 1 ATOM 2251 O OG1 . THR A 1 345 ? -22.663 3.358 -27.744 1.00 58.61 ? 345 THR A OG1 1 ATOM 2252 C CG2 . THR A 1 345 ? -21.966 4.904 -26.039 1.00 62.00 ? 345 THR A CG2 1 ATOM 2253 N N . GLU A 1 346 ? -24.007 3.791 -23.571 1.00 50.76 ? 346 GLU A N 1 ATOM 2254 C CA . GLU A 1 346 ? -24.108 4.374 -22.238 1.00 55.54 ? 346 GLU A CA 1 ATOM 2255 C C . GLU A 1 346 ? -24.066 3.303 -21.144 1.00 58.58 ? 346 GLU A C 1 ATOM 2256 O O . GLU A 1 346 ? -23.758 3.600 -19.989 1.00 65.50 ? 346 GLU A O 1 ATOM 2257 C CB . GLU A 1 346 ? -25.384 5.218 -22.125 1.00 61.20 ? 346 GLU A CB 1 ATOM 2258 C CG . GLU A 1 346 ? -25.433 6.138 -20.910 1.00 63.49 ? 346 GLU A CG 1 ATOM 2259 C CD . GLU A 1 346 ? -26.648 7.051 -20.912 1.00 58.63 ? 346 GLU A CD 1 ATOM 2260 O OE1 . GLU A 1 346 ? -26.700 7.976 -20.074 1.00 57.70 ? 346 GLU A OE1 1 ATOM 2261 O OE2 . GLU A 1 346 ? -27.549 6.844 -21.752 1.00 56.47 ? 346 GLU A OE2 1 ATOM 2262 N N . ALA A 1 347 ? -24.366 2.061 -21.513 1.00 55.44 ? 347 ALA A N 1 ATOM 2263 C CA . ALA A 1 347 ? -24.326 0.947 -20.568 1.00 56.53 ? 347 ALA A CA 1 ATOM 2264 C C . ALA A 1 347 ? -22.922 0.743 -20.003 1.00 62.11 ? 347 ALA A C 1 ATOM 2265 O O . ALA A 1 347 ? -22.742 0.668 -18.789 1.00 72.22 ? 347 ALA A O 1 ATOM 2266 C CB . ALA A 1 347 ? -24.828 -0.330 -21.224 1.00 50.63 ? 347 ALA A CB 1 ATOM 2267 N N . LEU A 1 348 ? -21.934 0.659 -20.889 1.00 53.40 ? 348 LEU A N 1 ATOM 2268 C CA . LEU A 1 348 ? -20.542 0.491 -20.479 1.00 56.06 ? 348 LEU A CA 1 ATOM 2269 C C . LEU A 1 348 ? -20.023 1.670 -19.655 1.00 63.64 ? 348 LEU A C 1 ATOM 2270 O O . LEU A 1 348 ? -19.378 1.477 -18.625 1.00 66.90 ? 348 LEU A O 1 ATOM 2271 C CB . LEU A 1 348 ? -19.639 0.292 -21.702 1.00 56.98 ? 348 LEU A CB 1 ATOM 2272 C CG . LEU A 1 348 ? -19.551 -1.100 -22.333 1.00 54.40 ? 348 LEU A CG 1 ATOM 2273 C CD1 . LEU A 1 348 ? -18.451 -1.142 -23.385 1.00 48.76 ? 348 LEU A CD1 1 ATOM 2274 C CD2 . LEU A 1 348 ? -19.313 -2.154 -21.268 1.00 50.96 ? 348 LEU A CD2 1 ATOM 2275 N N . ARG A 1 349 ? -20.311 2.883 -20.117 1.00 62.75 ? 349 ARG A N 1 ATOM 2276 C CA . ARG A 1 349 ? -19.750 4.102 -19.531 1.00 66.53 ? 349 ARG A CA 1 ATOM 2277 C C . ARG A 1 349 ? -19.993 4.256 -18.029 1.00 78.99 ? 349 ARG A C 1 ATOM 2278 O O . ARG A 1 349 ? -19.161 4.821 -17.318 1.00 87.36 ? 349 ARG A O 1 ATOM 2279 C CB . ARG A 1 349 ? -20.266 5.340 -20.271 1.00 59.60 ? 349 ARG A CB 1 ATOM 2280 C CG . ARG A 1 349 ? -19.914 5.372 -21.752 1.00 62.50 ? 349 ARG A CG 1 ATOM 2281 C CD . ARG A 1 349 ? -20.220 6.730 -22.369 1.00 67.14 ? 349 ARG A CD 1 ATOM 2282 N NE . ARG A 1 349 ? -19.871 6.778 -23.787 1.00 70.95 ? 349 ARG A NE 1 ATOM 2283 C CZ . ARG A 1 349 ? -18.649 7.025 -24.251 1.00 66.14 ? 349 ARG A CZ 1 ATOM 2284 N NH1 . ARG A 1 349 ? -17.648 7.243 -23.409 1.00 64.02 ? 349 ARG A NH1 1 ATOM 2285 N NH2 . ARG A 1 349 ? -18.428 7.050 -25.557 1.00 68.92 ? 349 ARG A NH2 1 ATOM 2286 N N . MET A 1 350 ? -21.129 3.755 -17.551 1.00 76.13 ? 350 MET A N 1 ATOM 2287 C CA . MET A 1 350 ? -21.492 3.897 -16.143 1.00 76.23 ? 350 MET A CA 1 ATOM 2288 C C . MET A 1 350 ? -20.893 2.792 -15.274 1.00 78.06 ? 350 MET A C 1 ATOM 2289 O O . MET A 1 350 ? -20.901 2.885 -14.046 1.00 77.38 ? 350 MET A O 1 ATOM 2290 C CB . MET A 1 350 ? -23.015 3.947 -15.974 1.00 72.60 ? 350 MET A CB 1 ATOM 2291 C CG . MET A 1 350 ? -23.735 2.647 -16.303 1.00 64.78 ? 350 MET A CG 1 ATOM 2292 S SD . MET A 1 350 ? -25.520 2.771 -16.062 1.00 58.97 ? 350 MET A SD 1 ATOM 2293 C CE . MET A 1 350 ? -26.016 1.063 -16.273 1.00 49.96 ? 350 MET A CE 1 ATOM 2294 N N . THR A 1 351 ? -20.370 1.752 -15.918 1.00 76.70 ? 351 THR A N 1 ATOM 2295 C CA . THR A 1 351 ? -19.705 0.667 -15.204 1.00 81.25 ? 351 THR A CA 1 ATOM 2296 C C . THR A 1 351 ? -18.331 1.122 -14.724 1.00 91.30 ? 351 THR A C 1 ATOM 2297 O O . THR A 1 351 ? -17.892 0.764 -13.629 1.00 85.41 ? 351 THR A O 1 ATOM 2298 C CB . THR A 1 351 ? -19.523 -0.576 -16.095 1.00 74.99 ? 351 THR A CB 1 ATOM 2299 O OG1 . THR A 1 351 ? -18.464 -0.349 -17.034 1.00 74.82 ? 351 THR A OG1 1 ATOM 2300 C CG2 . THR A 1 351 ? -20.800 -0.879 -16.849 1.00 67.39 ? 351 THR A CG2 1 ATOM 2301 N N . THR A 1 352 ? -17.658 1.910 -15.558 1.00 93.23 ? 352 THR A N 1 ATOM 2302 C CA . THR A 1 352 ? -16.359 2.479 -15.225 1.00 89.73 ? 352 THR A CA 1 ATOM 2303 C C . THR A 1 352 ? -16.504 3.449 -14.057 1.00 92.75 ? 352 THR A C 1 ATOM 2304 O O . THR A 1 352 ? -15.629 3.548 -13.194 1.00 82.33 ? 352 THR A O 1 ATOM 2305 C CB . THR A 1 352 ? -15.778 3.247 -16.429 1.00 76.62 ? 352 THR A CB 1 ATOM 2306 O OG1 . THR A 1 352 ? -16.435 4.515 -16.555 1.00 73.08 ? 352 THR A OG1 1 ATOM 2307 C CG2 . THR A 1 352 ? -15.974 2.457 -17.712 1.00 59.76 ? 352 THR A CG2 1 ATOM 2308 N N . LYS A 1 353 ? -17.633 4.151 -14.044 1.00 100.73 ? 353 LYS A N 1 ATOM 2309 C CA . LYS A 1 353 ? -17.927 5.181 -13.054 1.00 98.23 ? 353 LYS A CA 1 ATOM 2310 C C . LYS A 1 353 ? -18.657 4.617 -11.837 1.00 99.42 ? 353 LYS A C 1 ATOM 2311 O O . LYS A 1 353 ? -19.120 5.366 -10.977 1.00 103.76 ? 353 LYS A O 1 ATOM 2312 C CB . LYS A 1 353 ? -18.725 6.318 -13.695 1.00 97.64 ? 353 LYS A CB 1 ATOM 2313 C CG . LYS A 1 353 ? -17.986 6.997 -14.843 1.00 95.93 ? 353 LYS A CG 1 ATOM 2314 C CD . LYS A 1 353 ? -18.885 7.932 -15.638 1.00 98.60 ? 353 LYS A CD 1 ATOM 2315 C CE . LYS A 1 353 ? -18.137 8.514 -16.831 1.00 80.78 ? 353 LYS A CE 1 ATOM 2316 N NZ . LYS A 1 353 ? -18.998 9.378 -17.686 1.00 64.62 ? 353 LYS A NZ 1 ATOM 2317 N N . ALA A 1 354 ? -18.773 3.292 -11.784 1.00 94.12 ? 354 ALA A N 1 ATOM 2318 C CA . ALA A 1 354 ? -19.400 2.611 -10.654 1.00 96.36 ? 354 ALA A CA 1 ATOM 2319 C C . ALA A 1 354 ? -18.618 2.785 -9.348 1.00 114.84 ? 354 ALA A C 1 ATOM 2320 O O . ALA A 1 354 ? -19.082 2.371 -8.287 1.00 116.64 ? 354 ALA A O 1 ATOM 2321 C CB . ALA A 1 354 ? -19.596 1.132 -10.965 1.00 78.63 ? 354 ALA A CB 1 ATOM 2322 N N . ASP A 1 355 ? -17.434 3.388 -9.431 1.00 119.74 ? 355 ASP A N 1 ATOM 2323 C CA . ASP A 1 355 ? -16.592 3.619 -8.256 1.00 113.43 ? 355 ASP A CA 1 ATOM 2324 C C . ASP A 1 355 ? -17.138 4.728 -7.359 1.00 112.94 ? 355 ASP A C 1 ATOM 2325 O O . ASP A 1 355 ? -17.547 4.468 -6.227 1.00 116.73 ? 355 ASP A O 1 ATOM 2326 C CB . ASP A 1 355 ? -15.157 3.958 -8.673 1.00 110.05 ? 355 ASP A CB 1 ATOM 2327 C CG . ASP A 1 355 ? -14.255 2.740 -8.709 1.00 115.53 ? 355 ASP A CG 1 ATOM 2328 O OD1 . ASP A 1 355 ? -14.576 1.742 -8.029 1.00 111.23 ? 355 ASP A OD1 1 ATOM 2329 O OD2 . ASP A 1 355 ? -13.221 2.784 -9.409 1.00 114.86 ? 355 ASP A OD2 1 ATOM 2330 N N . GLN A 1 356 ? -17.128 5.961 -7.862 1.00 113.40 ? 356 GLN A N 1 ATOM 2331 C CA . GLN A 1 356 ? -17.654 7.102 -7.115 1.00 115.07 ? 356 GLN A CA 1 ATOM 2332 C C . GLN A 1 356 ? -19.105 6.862 -6.714 1.00 125.20 ? 356 GLN A C 1 ATOM 2333 O O . GLN A 1 356 ? -19.415 6.703 -5.534 1.00 123.90 ? 356 GLN A O 1 ATOM 2334 C CB . GLN A 1 356 ? -17.559 8.392 -7.936 1.00 108.78 ? 356 GLN A CB 1 ATOM 2335 C CG . GLN A 1 356 ? -16.173 8.703 -8.469 1.00 107.30 ? 356 GLN A CG 1 ATOM 2336 C CD . GLN A 1 356 ? -16.010 8.316 -9.924 1.00 121.88 ? 356 GLN A CD 1 ATOM 2337 O OE1 . GLN A 1 356 ? -16.936 8.462 -10.724 1.00 111.99 ? 356 GLN A OE1 1 ATOM 2338 N NE2 . GLN A 1 356 ? -14.831 7.816 -10.276 1.00 126.15 ? 356 GLN A NE2 1 ATOM 2339 N N . HIS A 1 357 ? -19.987 6.835 -7.707 1.00 120.33 ? 357 HIS A N 1 ATOM 2340 C CA . HIS A 1 357 ? -21.394 6.546 -7.472 1.00 110.39 ? 357 HIS A CA 1 ATOM 2341 C C . HIS A 1 357 ? -21.733 5.130 -7.924 1.00 109.86 ? 357 HIS A C 1 ATOM 2342 O O . HIS A 1 357 ? -21.599 4.796 -9.101 1.00 103.69 ? 357 HIS A O 1 ATOM 2343 C CB . HIS A 1 357 ? -22.274 7.560 -8.193 1.00 99.53 ? 357 HIS A CB 1 ATOM 2344 N N . ASP A 1 358 ? -22.155 4.297 -6.976 1.00 116.65 ? 358 ASP A N 1 ATOM 2345 C CA . ASP A 1 358 ? -22.671 2.972 -7.292 1.00 115.92 ? 358 ASP A CA 1 ATOM 2346 C C . ASP A 1 358 ? -24.032 3.148 -7.943 1.00 102.96 ? 358 ASP A C 1 ATOM 2347 O O . ASP A 1 358 ? -24.484 2.302 -8.714 1.00 92.72 ? 358 ASP A O 1 ATOM 2348 C CB . ASP A 1 358 ? -22.821 2.128 -6.026 1.00 120.72 ? 358 ASP A CB 1 ATOM 2349 C CG . ASP A 1 358 ? -21.498 1.858 -5.339 1.00 123.41 ? 358 ASP A CG 1 ATOM 2350 O OD1 . ASP A 1 358 ? -20.485 1.668 -6.043 1.00 116.92 ? 358 ASP A OD1 1 ATOM 2351 O OD2 . ASP A 1 358 ? -21.472 1.835 -4.091 1.00 126.56 ? 358 ASP A OD2 1 ATOM 2352 N N . ILE A 1 359 ? -24.680 4.261 -7.616 1.00 99.12 ? 359 ILE A N 1 ATOM 2353 C CA . ILE A 1 359 ? -25.979 4.595 -8.181 1.00 95.95 ? 359 ILE A CA 1 ATOM 2354 C C . ILE A 1 359 ? -25.848 5.752 -9.166 1.00 92.76 ? 359 ILE A C 1 ATOM 2355 O O . ILE A 1 359 ? -25.543 6.881 -8.778 1.00 90.73 ? 359 ILE A O 1 ATOM 2356 C CB . ILE A 1 359 ? -27.010 4.965 -7.084 1.00 94.55 ? 359 ILE A CB 1 ATOM 2357 C CG1 . ILE A 1 359 ? -27.314 3.760 -6.188 1.00 84.33 ? 359 ILE A CG1 1 ATOM 2358 C CG2 . ILE A 1 359 ? -28.298 5.488 -7.708 1.00 80.68 ? 359 ILE A CG2 1 ATOM 2359 C CD1 . ILE A 1 359 ? -26.364 3.592 -5.018 1.00 84.87 ? 359 ILE A CD1 1 ATOM 2360 N N . ASN A 1 360 ? -26.063 5.462 -10.445 1.00 84.04 ? 360 ASN A N 1 ATOM 2361 C CA . ASN A 1 360 ? -26.142 6.510 -11.452 1.00 77.54 ? 360 ASN A CA 1 ATOM 2362 C C . ASN A 1 360 ? -27.602 6.754 -11.793 1.00 75.01 ? 360 ASN A C 1 ATOM 2363 O O . ASN A 1 360 ? -28.240 5.934 -12.451 1.00 72.03 ? 360 ASN A O 1 ATOM 2364 C CB . ASN A 1 360 ? -25.378 6.112 -12.714 1.00 72.10 ? 360 ASN A CB 1 ATOM 2365 C CG . ASN A 1 360 ? -23.912 5.846 -12.451 1.00 84.91 ? 360 ASN A CG 1 ATOM 2366 O OD1 . ASN A 1 360 ? -23.529 4.733 -12.092 1.00 87.47 ? 360 ASN A OD1 1 ATOM 2367 N ND2 . ASN A 1 360 ? -23.081 6.866 -12.634 1.00 93.56 ? 360 ASN A ND2 1 ATOM 2368 N N . GLU A 1 361 ? -28.127 7.890 -11.351 1.00 73.94 ? 361 GLU A N 1 ATOM 2369 C CA . GLU A 1 361 ? -29.539 8.188 -11.532 1.00 69.21 ? 361 GLU A CA 1 ATOM 2370 C C . GLU A 1 361 ? -29.829 8.610 -12.968 1.00 65.51 ? 361 GLU A C 1 ATOM 2371 O O . GLU A 1 361 ? -30.767 8.116 -13.593 1.00 66.27 ? 361 GLU A O 1 ATOM 2372 C CB . GLU A 1 361 ? -29.984 9.274 -10.548 1.00 72.56 ? 361 GLU A CB 1 ATOM 2373 C CG . GLU A 1 361 ? -31.478 9.560 -10.560 1.00 70.40 ? 361 GLU A CG 1 ATOM 2374 C CD . GLU A 1 361 ? -31.923 10.400 -9.377 1.00 72.92 ? 361 GLU A CD 1 ATOM 2375 O OE1 . GLU A 1 361 ? -31.141 10.534 -8.411 1.00 73.33 ? 361 GLU A OE1 1 ATOM 2376 O OE2 . GLU A 1 361 ? -33.056 10.923 -9.412 1.00 80.55 ? 361 GLU A OE2 1 ATOM 2377 N N . GLU A 1 362 ? -29.006 9.509 -13.495 1.00 63.38 ? 362 GLU A N 1 ATOM 2378 C CA . GLU A 1 362 ? -29.214 10.022 -14.842 1.00 66.26 ? 362 GLU A CA 1 ATOM 2379 C C . GLU A 1 362 ? -28.937 8.950 -15.895 1.00 61.65 ? 362 GLU A C 1 ATOM 2380 O O . GLU A 1 362 ? -29.400 9.054 -17.029 1.00 61.85 ? 362 GLU A O 1 ATOM 2381 C CB . GLU A 1 362 ? -28.348 11.259 -15.092 1.00 71.93 ? 362 GLU A CB 1 ATOM 2382 C CG . GLU A 1 362 ? -28.861 12.153 -16.213 1.00 78.38 ? 362 GLU A CG 1 ATOM 2383 C CD . GLU A 1 362 ? -27.943 13.328 -16.503 1.00 99.39 ? 362 GLU A CD 1 ATOM 2384 O OE1 . GLU A 1 362 ? -26.720 13.205 -16.280 1.00 112.34 ? 362 GLU A OE1 1 ATOM 2385 O OE2 . GLU A 1 362 ? -28.448 14.376 -16.958 1.00 109.60 ? 362 GLU A OE2 1 ATOM 2386 N N . SER A 1 363 ? -28.182 7.921 -15.519 1.00 60.87 ? 363 SER A N 1 ATOM 2387 C CA . SER A 1 363 ? -27.930 6.800 -16.423 1.00 62.24 ? 363 SER A CA 1 ATOM 2388 C C . SER A 1 363 ? -29.005 5.716 -16.330 1.00 59.64 ? 363 SER A C 1 ATOM 2389 O O . SER A 1 363 ? -29.083 4.844 -17.193 1.00 65.36 ? 363 SER A O 1 ATOM 2390 C CB . SER A 1 363 ? -26.543 6.201 -16.192 1.00 61.55 ? 363 SER A CB 1 ATOM 2391 O OG . SER A 1 363 ? -25.541 6.943 -16.866 1.00 56.40 ? 363 SER A OG 1 ATOM 2392 N N . TYR A 1 364 ? -29.834 5.769 -15.291 1.00 53.72 ? 364 TYR A N 1 ATOM 2393 C CA . TYR A 1 364 ? -30.955 4.837 -15.184 1.00 51.12 ? 364 TYR A CA 1 ATOM 2394 C C . TYR A 1 364 ? -32.095 5.272 -16.092 1.00 47.12 ? 364 TYR A C 1 ATOM 2395 O O . TYR A 1 364 ? -32.692 4.451 -16.784 1.00 44.12 ? 364 TYR A O 1 ATOM 2396 C CB . TYR A 1 364 ? -31.452 4.716 -13.741 1.00 57.94 ? 364 TYR A CB 1 ATOM 2397 C CG . TYR A 1 364 ? -32.625 3.767 -13.572 1.00 51.29 ? 364 TYR A CG 1 ATOM 2398 C CD1 . TYR A 1 364 ? -32.423 2.407 -13.376 1.00 48.55 ? 364 TYR A CD1 1 ATOM 2399 C CD2 . TYR A 1 364 ? -33.934 4.232 -13.606 1.00 48.80 ? 364 TYR A CD2 1 ATOM 2400 C CE1 . TYR A 1 364 ? -33.489 1.538 -13.221 1.00 44.14 ? 364 TYR A CE1 1 ATOM 2401 C CE2 . TYR A 1 364 ? -35.005 3.371 -13.448 1.00 48.33 ? 364 TYR A CE2 1 ATOM 2402 C CZ . TYR A 1 364 ? -34.777 2.026 -13.257 1.00 43.72 ? 364 TYR A CZ 1 ATOM 2403 O OH . TYR A 1 364 ? -35.843 1.170 -13.102 1.00 33.83 ? 364 TYR A OH 1 ATOM 2404 N N . TYR A 1 365 ? -32.391 6.569 -16.078 1.00 50.25 ? 365 TYR A N 1 ATOM 2405 C CA . TYR A 1 365 ? -33.480 7.131 -16.873 1.00 53.46 ? 365 TYR A CA 1 ATOM 2406 C C . TYR A 1 365 ? -33.173 7.046 -18.365 1.00 51.49 ? 365 TYR A C 1 ATOM 2407 O O . TYR A 1 365 ? -34.002 6.590 -19.155 1.00 46.00 ? 365 TYR A O 1 ATOM 2408 C CB . TYR A 1 365 ? -33.733 8.593 -16.491 1.00 54.74 ? 365 TYR A CB 1 ATOM 2409 C CG . TYR A 1 365 ? -34.247 8.813 -15.082 1.00 59.89 ? 365 TYR A CG 1 ATOM 2410 C CD1 . TYR A 1 365 ? -34.549 7.743 -14.248 1.00 57.40 ? 365 TYR A CD1 1 ATOM 2411 C CD2 . TYR A 1 365 ? -34.442 10.097 -14.591 1.00 69.67 ? 365 TYR A CD2 1 ATOM 2412 C CE1 . TYR A 1 365 ? -35.019 7.948 -12.965 1.00 61.46 ? 365 TYR A CE1 1 ATOM 2413 C CE2 . TYR A 1 365 ? -34.915 10.310 -13.310 1.00 68.39 ? 365 TYR A CE2 1 ATOM 2414 C CZ . TYR A 1 365 ? -35.201 9.233 -12.501 1.00 65.57 ? 365 TYR A CZ 1 ATOM 2415 O OH . TYR A 1 365 ? -35.671 9.438 -11.225 1.00 65.36 ? 365 TYR A OH 1 ATOM 2416 N N . HIS A 1 366 ? -31.978 7.499 -18.737 1.00 51.46 ? 366 HIS A N 1 ATOM 2417 C CA . HIS A 1 366 ? -31.531 7.489 -20.125 1.00 46.12 ? 366 HIS A CA 1 ATOM 2418 C C . HIS A 1 366 ? -31.582 6.089 -20.742 1.00 45.01 ? 366 HIS A C 1 ATOM 2419 O O . HIS A 1 366 ? -32.140 5.906 -21.823 1.00 51.10 ? 366 HIS A O 1 ATOM 2420 C CB . HIS A 1 366 ? -30.117 8.070 -20.231 1.00 45.54 ? 366 HIS A CB 1 ATOM 2421 C CG . HIS A 1 366 ? -30.072 9.568 -20.248 1.00 47.73 ? 366 HIS A CG 1 ATOM 2422 N ND1 . HIS A 1 366 ? -29.414 10.281 -21.228 1.00 50.56 ? 366 HIS A ND1 1 ATOM 2423 C CD2 . HIS A 1 366 ? -30.602 10.489 -19.408 1.00 53.45 ? 366 HIS A CD2 1 ATOM 2424 C CE1 . HIS A 1 366 ? -29.539 11.574 -20.990 1.00 52.83 ? 366 HIS A CE1 1 ATOM 2425 N NE2 . HIS A 1 366 ? -30.255 11.728 -19.892 1.00 55.05 ? 366 HIS A NE2 1 ATOM 2426 N N . ILE A 1 367 ? -31.010 5.107 -20.050 1.00 39.20 ? 367 ILE A N 1 ATOM 2427 C CA . ILE A 1 367 ? -31.014 3.728 -20.538 1.00 38.17 ? 367 ILE A CA 1 ATOM 2428 C C . ILE A 1 367 ? -32.424 3.137 -20.615 1.00 39.88 ? 367 ILE A C 1 ATOM 2429 O O . ILE A 1 367 ? -32.801 2.558 -21.634 1.00 41.54 ? 367 ILE A O 1 ATOM 2430 C CB . ILE A 1 367 ? -30.096 2.814 -19.694 1.00 35.07 ? 367 ILE A CB 1 ATOM 2431 C CG1 . ILE A 1 367 ? -28.627 3.142 -19.972 1.00 41.87 ? 367 ILE A CG1 1 ATOM 2432 C CG2 . ILE A 1 367 ? -30.370 1.346 -19.991 1.00 29.56 ? 367 ILE A CG2 1 ATOM 2433 C CD1 . ILE A 1 367 ? -27.652 2.172 -19.342 1.00 49.51 ? 367 ILE A CD1 1 ATOM 2434 N N . ALA A 1 368 ? -33.198 3.291 -19.544 1.00 42.47 ? 368 ALA A N 1 ATOM 2435 C CA . ALA A 1 368 ? -34.571 2.790 -19.516 1.00 39.65 ? 368 ALA A CA 1 ATOM 2436 C C . ALA A 1 368 ? -35.407 3.384 -20.645 1.00 35.69 ? 368 ALA A C 1 ATOM 2437 O O . ALA A 1 368 ? -36.065 2.657 -21.385 1.00 35.48 ? 368 ALA A O 1 ATOM 2438 C CB . ALA A 1 368 ? -35.219 3.070 -18.170 1.00 38.80 ? 368 ALA A CB 1 ATOM 2439 N N . ALA A 1 369 ? -35.366 4.707 -20.779 1.00 35.14 ? 369 ALA A N 1 ATOM 2440 C CA . ALA A 1 369 ? -36.114 5.398 -21.825 1.00 38.12 ? 369 ALA A CA 1 ATOM 2441 C C . ALA A 1 369 ? -35.706 4.918 -23.215 1.00 38.42 ? 369 ALA A C 1 ATOM 2442 O O . ALA A 1 369 ? -36.497 4.968 -24.157 1.00 36.68 ? 369 ALA A O 1 ATOM 2443 C CB . ALA A 1 369 ? -35.930 6.898 -21.706 1.00 38.76 ? 369 ALA A CB 1 ATOM 2444 N N . ARG A 1 370 ? -34.464 4.456 -23.329 1.00 38.63 ? 370 ARG A N 1 ATOM 2445 C CA . ARG A 1 370 ? -33.939 3.909 -24.574 1.00 37.45 ? 370 ARG A CA 1 ATOM 2446 C C . ARG A 1 370 ? -34.473 2.503 -24.857 1.00 37.58 ? 370 ARG A C 1 ATOM 2447 O O . ARG A 1 370 ? -34.727 2.152 -26.011 1.00 39.07 ? 370 ARG A O 1 ATOM 2448 C CB . ARG A 1 370 ? -32.410 3.903 -24.542 1.00 34.32 ? 370 ARG A CB 1 ATOM 2449 C CG . ARG A 1 370 ? -31.778 5.206 -24.993 1.00 37.89 ? 370 ARG A CG 1 ATOM 2450 C CD . ARG A 1 370 ? -31.516 5.183 -26.483 1.00 43.63 ? 370 ARG A CD 1 ATOM 2451 N NE . ARG A 1 370 ? -32.271 6.191 -27.220 1.00 44.33 ? 370 ARG A NE 1 ATOM 2452 C CZ . ARG A 1 370 ? -31.840 7.426 -27.449 1.00 49.34 ? 370 ARG A CZ 1 ATOM 2453 N NH1 . ARG A 1 370 ? -30.659 7.819 -26.989 1.00 52.68 ? 370 ARG A NH1 1 ATOM 2454 N NH2 . ARG A 1 370 ? -32.592 8.270 -28.139 1.00 47.41 ? 370 ARG A NH2 1 ATOM 2455 N N . ILE A 1 371 ? -34.640 1.704 -23.804 1.00 35.36 ? 371 ILE A N 1 ATOM 2456 C CA . ILE A 1 371 ? -35.244 0.379 -23.929 1.00 31.70 ? 371 ILE A CA 1 ATOM 2457 C C . ILE A 1 371 ? -36.692 0.515 -24.377 1.00 28.31 ? 371 ILE A C 1 ATOM 2458 O O . ILE A 1 371 ? -37.128 -0.133 -25.327 1.00 27.96 ? 371 ILE A O 1 ATOM 2459 C CB . ILE A 1 371 ? -35.240 -0.386 -22.588 1.00 26.97 ? 371 ILE A CB 1 ATOM 2460 C CG1 . ILE A 1 371 ? -33.837 -0.441 -21.990 1.00 34.47 ? 371 ILE A CG1 1 ATOM 2461 C CG2 . ILE A 1 371 ? -35.769 -1.796 -22.773 1.00 22.30 ? 371 ILE A CG2 1 ATOM 2462 C CD1 . ILE A 1 371 ? -33.794 -1.108 -20.632 1.00 44.78 ? 371 ILE A CD1 1 ATOM 2463 N N . ALA A 1 372 ? -37.429 1.367 -23.673 1.00 27.47 ? 372 ALA A N 1 ATOM 2464 C CA . ALA A 1 372 ? -38.842 1.593 -23.942 1.00 29.36 ? 372 ALA A CA 1 ATOM 2465 C C . ALA A 1 372 ? -39.086 2.072 -25.368 1.00 31.57 ? 372 ALA A C 1 ATOM 2466 O O . ALA A 1 372 ? -39.924 1.523 -26.080 1.00 35.06 ? 372 ALA A O 1 ATOM 2467 C CB . ALA A 1 372 ? -39.407 2.583 -22.948 1.00 31.66 ? 372 ALA A CB 1 ATOM 2468 N N . THR A 1 373 ? -38.350 3.101 -25.778 1.00 30.39 ? 373 THR A N 1 ATOM 2469 C CA . THR A 1 373 ? -38.502 3.672 -27.113 1.00 32.39 ? 373 THR A CA 1 ATOM 2470 C C . THR A 1 373 ? -38.050 2.722 -28.222 1.00 30.64 ? 373 THR A C 1 ATOM 2471 O O . THR A 1 373 ? -38.438 2.883 -29.378 1.00 28.92 ? 373 THR A O 1 ATOM 2472 C CB . THR A 1 373 ? -37.753 5.012 -27.245 1.00 34.68 ? 373 THR A CB 1 ATOM 2473 O OG1 . THR A 1 373 ? -36.604 5.000 -26.391 1.00 41.52 ? 373 THR A OG1 1 ATOM 2474 C CG2 . THR A 1 373 ? -38.651 6.167 -26.846 1.00 34.21 ? 373 THR A CG2 1 ATOM 2475 N N . SER A 1 374 ? -37.231 1.736 -27.870 1.00 32.61 ? 374 SER A N 1 ATOM 2476 C CA . SER A 1 374 ? -36.774 0.753 -28.847 1.00 30.72 ? 374 SER A CA 1 ATOM 2477 C C . SER A 1 374 ? -37.915 -0.164 -29.280 1.00 29.99 ? 374 SER A C 1 ATOM 2478 O O . SER A 1 374 ? -38.124 -0.381 -30.472 1.00 31.40 ? 374 SER A O 1 ATOM 2479 C CB . SER A 1 374 ? -35.605 -0.069 -28.295 1.00 26.63 ? 374 SER A CB 1 ATOM 2480 O OG . SER A 1 374 ? -36.021 -0.912 -27.234 1.00 24.79 ? 374 SER A OG 1 ATOM 2481 N N . ILE A 1 375 ? -38.647 -0.699 -28.306 1.00 29.41 ? 375 ILE A N 1 ATOM 2482 C CA . ILE A 1 375 ? -39.795 -1.555 -28.592 1.00 26.49 ? 375 ILE A CA 1 ATOM 2483 C C . ILE A 1 375 ? -40.905 -0.757 -29.281 1.00 29.14 ? 375 ILE A C 1 ATOM 2484 O O . ILE A 1 375 ? -41.611 -1.282 -30.139 1.00 33.88 ? 375 ILE A O 1 ATOM 2485 C CB . ILE A 1 375 ? -40.345 -2.234 -27.312 1.00 24.62 ? 375 ILE A CB 1 ATOM 2486 C CG1 . ILE A 1 375 ? -39.244 -3.013 -26.591 1.00 30.01 ? 375 ILE A CG1 1 ATOM 2487 C CG2 . ILE A 1 375 ? -41.516 -3.155 -27.644 1.00 22.72 ? 375 ILE A CG2 1 ATOM 2488 C CD1 . ILE A 1 375 ? -38.769 -4.240 -27.336 1.00 29.71 ? 375 ILE A CD1 1 ATOM 2489 N N . PHE A 1 376 ? -41.046 0.515 -28.914 1.00 30.64 ? 376 PHE A N 1 ATOM 2490 C CA . PHE A 1 376 ? -42.030 1.386 -29.555 1.00 33.52 ? 376 PHE A CA 1 ATOM 2491 C C . PHE A 1 376 ? -41.695 1.595 -31.026 1.00 36.94 ? 376 PHE A C 1 ATOM 2492 O O . PHE A 1 376 ? -42.586 1.703 -31.870 1.00 32.30 ? 376 PHE A O 1 ATOM 2493 C CB . PHE A 1 376 ? -42.119 2.736 -28.842 1.00 30.80 ? 376 PHE A CB 1 ATOM 2494 C CG . PHE A 1 376 ? -42.787 3.811 -29.657 1.00 26.11 ? 376 PHE A CG 1 ATOM 2495 C CD1 . PHE A 1 376 ? -44.155 3.798 -29.864 1.00 26.50 ? 376 PHE A CD1 1 ATOM 2496 C CD2 . PHE A 1 376 ? -42.043 4.840 -30.211 1.00 32.36 ? 376 PHE A CD2 1 ATOM 2497 C CE1 . PHE A 1 376 ? -44.766 4.790 -30.614 1.00 29.98 ? 376 PHE A CE1 1 ATOM 2498 C CE2 . PHE A 1 376 ? -42.648 5.832 -30.959 1.00 30.21 ? 376 PHE A CE2 1 ATOM 2499 C CZ . PHE A 1 376 ? -44.011 5.808 -31.161 1.00 26.57 ? 376 PHE A CZ 1 ATOM 2500 N N . ALA A 1 377 ? -40.401 1.658 -31.319 1.00 39.27 ? 377 ALA A N 1 ATOM 2501 C CA . ALA A 1 377 ? -39.925 1.776 -32.687 1.00 32.23 ? 377 ALA A CA 1 ATOM 2502 C C . ALA A 1 377 ? -40.220 0.498 -33.470 1.00 33.16 ? 377 ALA A C 1 ATOM 2503 O O . ALA A 1 377 ? -40.619 0.556 -34.629 1.00 39.34 ? 377 ALA A O 1 ATOM 2504 C CB . ALA A 1 377 ? -38.437 2.088 -32.704 1.00 32.61 ? 377 ALA A CB 1 ATOM 2505 N N . LEU A 1 378 ? -40.035 -0.651 -32.825 1.00 30.83 ? 378 LEU A N 1 ATOM 2506 C CA . LEU A 1 378 ? -40.220 -1.946 -33.481 1.00 29.73 ? 378 LEU A CA 1 ATOM 2507 C C . LEU A 1 378 ? -41.684 -2.245 -33.815 1.00 32.24 ? 378 LEU A C 1 ATOM 2508 O O . LEU A 1 378 ? -41.984 -2.763 -34.889 1.00 39.42 ? 378 LEU A O 1 ATOM 2509 C CB . LEU A 1 378 ? -39.614 -3.069 -32.633 1.00 28.42 ? 378 LEU A CB 1 ATOM 2510 C CG . LEU A 1 378 ? -39.207 -4.375 -33.324 1.00 28.15 ? 378 LEU A CG 1 ATOM 2511 C CD1 . LEU A 1 378 ? -40.289 -5.428 -33.205 1.00 25.87 ? 378 LEU A CD1 1 ATOM 2512 C CD2 . LEU A 1 378 ? -38.859 -4.138 -34.787 1.00 31.40 ? 378 LEU A CD2 1 ATOM 2513 N N . SER A 1 379 ? -42.592 -1.927 -32.897 1.00 30.16 ? 379 SER A N 1 ATOM 2514 C CA . SER A 1 379 ? -44.020 -2.062 -33.181 1.00 29.15 ? 379 SER A CA 1 ATOM 2515 C C . SER A 1 379 ? -44.413 -1.131 -34.315 1.00 31.42 ? 379 SER A C 1 ATOM 2516 O O . SER A 1 379 ? -45.154 -1.510 -35.219 1.00 36.95 ? 379 SER A O 1 ATOM 2517 C CB . SER A 1 379 ? -44.861 -1.742 -31.944 1.00 29.06 ? 379 SER A CB 1 ATOM 2518 O OG . SER A 1 379 ? -46.198 -1.453 -32.301 1.00 22.65 ? 379 SER A OG 1 ATOM 2519 N N . GLU A 1 380 ? -43.901 0.091 -34.264 1.00 30.54 ? 380 GLU A N 1 ATOM 2520 C CA . GLU A 1 380 ? -44.301 1.121 -35.210 1.00 31.84 ? 380 GLU A CA 1 ATOM 2521 C C . GLU A 1 380 ? -43.617 0.986 -36.573 1.00 33.66 ? 380 GLU A C 1 ATOM 2522 O O . GLU A 1 380 ? -44.163 1.413 -37.588 1.00 38.14 ? 380 GLU A O 1 ATOM 2523 C CB . GLU A 1 380 ? -44.062 2.502 -34.604 1.00 31.89 ? 380 GLU A CB 1 ATOM 2524 C CG . GLU A 1 380 ? -45.147 3.507 -34.918 1.00 28.63 ? 380 GLU A CG 1 ATOM 2525 C CD . GLU A 1 380 ? -46.477 3.183 -34.271 1.00 29.40 ? 380 GLU A CD 1 ATOM 2526 O OE1 . GLU A 1 380 ? -47.493 3.748 -34.721 1.00 32.21 ? 380 GLU A OE1 1 ATOM 2527 O OE2 . GLU A 1 380 ? -46.512 2.380 -33.315 1.00 28.94 ? 380 GLU A OE2 1 ATOM 2528 N N . MET A 1 381 ? -42.426 0.398 -36.596 1.00 34.55 ? 381 MET A N 1 ATOM 2529 C CA . MET A 1 381 ? -41.769 0.086 -37.860 1.00 37.21 ? 381 MET A CA 1 ATOM 2530 C C . MET A 1 381 ? -42.547 -1.041 -38.536 1.00 39.10 ? 381 MET A C 1 ATOM 2531 O O . MET A 1 381 ? -42.666 -1.087 -39.761 1.00 43.80 ? 381 MET A O 1 ATOM 2532 C CB . MET A 1 381 ? -40.308 -0.317 -37.630 1.00 37.37 ? 381 MET A CB 1 ATOM 2533 C CG . MET A 1 381 ? -39.473 -0.457 -38.896 1.00 37.68 ? 381 MET A CG 1 ATOM 2534 S SD . MET A 1 381 ? -39.428 1.052 -39.885 1.00 37.95 ? 381 MET A SD 1 ATOM 2535 C CE . MET A 1 381 ? -38.560 0.480 -41.345 1.00 36.23 ? 381 MET A CE 1 ATOM 2536 N N . GLY A 1 382 ? -43.095 -1.937 -37.720 1.00 33.61 ? 382 GLY A N 1 ATOM 2537 C CA . GLY A 1 382 ? -43.860 -3.064 -38.220 1.00 33.67 ? 382 GLY A CA 1 ATOM 2538 C C . GLY A 1 382 ? -45.260 -2.714 -38.683 1.00 37.89 ? 382 GLY A C 1 ATOM 2539 O O . GLY A 1 382 ? -45.749 -3.279 -39.659 1.00 42.43 ? 382 GLY A O 1 ATOM 2540 N N . ARG A 1 383 ? -45.913 -1.792 -37.982 1.00 37.86 ? 383 ARG A N 1 ATOM 2541 C CA . ARG A 1 383 ? -47.244 -1.341 -38.378 1.00 35.56 ? 383 ARG A CA 1 ATOM 2542 C C . ARG A 1 383 ? -47.147 -0.513 -39.654 1.00 37.34 ? 383 ARG A C 1 ATOM 2543 O O . ARG A 1 383 ? -47.996 -0.620 -40.535 1.00 47.24 ? 383 ARG A O 1 ATOM 2544 C CB . ARG A 1 383 ? -47.910 -0.525 -37.260 1.00 35.78 ? 383 ARG A CB 1 ATOM 2545 C CG . ARG A 1 383 ? -49.358 -0.121 -37.551 1.00 36.12 ? 383 ARG A CG 1 ATOM 2546 C CD . ARG A 1 383 ? -49.760 1.128 -36.779 1.00 30.69 ? 383 ARG A CD 1 ATOM 2547 N NE . ARG A 1 383 ? -48.816 2.218 -37.005 1.00 34.86 ? 383 ARG A NE 1 ATOM 2548 C CZ . ARG A 1 383 ? -49.157 3.484 -37.227 1.00 38.00 ? 383 ARG A CZ 1 ATOM 2549 N NH1 . ARG A 1 383 ? -50.433 3.841 -37.251 1.00 42.54 ? 383 ARG A NH1 1 ATOM 2550 N NH2 . ARG A 1 383 ? -48.215 4.395 -37.423 1.00 34.70 ? 383 ARG A NH2 1 ATOM 2551 N N . THR A 1 384 ? -46.095 0.298 -39.748 1.00 33.41 ? 384 THR A N 1 ATOM 2552 C CA . THR A 1 384 ? -45.876 1.174 -40.899 1.00 38.62 ? 384 THR A CA 1 ATOM 2553 C C . THR A 1 384 ? -45.496 0.419 -42.176 1.00 46.10 ? 384 THR A C 1 ATOM 2554 O O . THR A 1 384 ? -46.105 0.620 -43.228 1.00 53.29 ? 384 THR A O 1 ATOM 2555 C CB . THR A 1 384 ? -44.810 2.252 -40.593 1.00 35.56 ? 384 THR A CB 1 ATOM 2556 O OG1 . THR A 1 384 ? -45.405 3.318 -39.842 1.00 31.67 ? 384 THR A OG1 1 ATOM 2557 C CG2 . THR A 1 384 ? -44.224 2.820 -41.876 1.00 46.25 ? 384 THR A CG2 1 ATOM 2558 N N . THR A 1 385 ? -44.488 -0.443 -42.087 1.00 39.22 ? 385 THR A N 1 ATOM 2559 C CA . THR A 1 385 ? -44.012 -1.161 -43.267 1.00 39.37 ? 385 THR A CA 1 ATOM 2560 C C . THR A 1 385 ? -44.698 -2.513 -43.455 1.00 40.92 ? 385 THR A C 1 ATOM 2561 O O . THR A 1 385 ? -44.437 -3.217 -44.428 1.00 44.10 ? 385 THR A O 1 ATOM 2562 C CB . THR A 1 385 ? -42.487 -1.341 -43.243 1.00 49.04 ? 385 THR A CB 1 ATOM 2563 O OG1 . THR A 1 385 ? -41.943 -0.628 -42.127 1.00 54.71 ? 385 THR A OG1 1 ATOM 2564 C CG2 . THR A 1 385 ? -41.878 -0.801 -44.531 1.00 59.01 ? 385 THR A CG2 1 ATOM 2565 N N . GLU A 1 386 ? -45.556 -2.874 -42.506 1.00 46.62 ? 386 GLU A N 1 ATOM 2566 C CA . GLU A 1 386 ? -46.449 -4.030 -42.635 1.00 52.00 ? 386 GLU A CA 1 ATOM 2567 C C . GLU A 1 386 ? -45.762 -5.401 -42.648 1.00 48.52 ? 386 GLU A C 1 ATOM 2568 O O . GLU A 1 386 ? -46.434 -6.432 -42.702 1.00 51.48 ? 386 GLU A O 1 ATOM 2569 C CB . GLU A 1 386 ? -47.390 -3.870 -43.836 1.00 53.92 ? 386 GLU A CB 1 ATOM 2570 C CG . GLU A 1 386 ? -48.134 -2.542 -43.847 1.00 63.62 ? 386 GLU A CG 1 ATOM 2571 C CD . GLU A 1 386 ? -49.462 -2.618 -44.570 1.00 85.64 ? 386 GLU A CD 1 ATOM 2572 O OE1 . GLU A 1 386 ? -49.942 -3.744 -44.818 1.00 94.79 ? 386 GLU A OE1 1 ATOM 2573 O OE2 . GLU A 1 386 ? -50.028 -1.551 -44.888 1.00 83.99 ? 386 GLU A OE2 1 ATOM 2574 N N . TYR A 1 387 ? -44.434 -5.417 -42.602 1.00 40.05 ? 387 TYR A N 1 ATOM 2575 C CA . TYR A 1 387 ? -43.706 -6.679 -42.523 1.00 40.29 ? 387 TYR A CA 1 ATOM 2576 C C . TYR A 1 387 ? -42.684 -6.667 -41.394 1.00 47.05 ? 387 TYR A C 1 ATOM 2577 O O . TYR A 1 387 ? -42.119 -5.624 -41.067 1.00 48.57 ? 387 TYR A O 1 ATOM 2578 C CB . TYR A 1 387 ? -43.016 -6.992 -43.851 1.00 41.48 ? 387 TYR A CB 1 ATOM 2579 C CG . TYR A 1 387 ? -41.768 -6.181 -44.112 1.00 42.00 ? 387 TYR A CG 1 ATOM 2580 C CD1 . TYR A 1 387 ? -41.848 -4.845 -44.471 1.00 43.87 ? 387 TYR A CD1 1 ATOM 2581 C CD2 . TYR A 1 387 ? -40.509 -6.758 -44.014 1.00 42.30 ? 387 TYR A CD2 1 ATOM 2582 C CE1 . TYR A 1 387 ? -40.710 -4.103 -44.718 1.00 49.89 ? 387 TYR A CE1 1 ATOM 2583 C CE2 . TYR A 1 387 ? -39.365 -6.022 -44.259 1.00 44.16 ? 387 TYR A CE2 1 ATOM 2584 C CZ . TYR A 1 387 ? -39.472 -4.693 -44.611 1.00 48.86 ? 387 TYR A CZ 1 ATOM 2585 O OH . TYR A 1 387 ? -38.344 -3.946 -44.858 1.00 51.23 ? 387 TYR A OH 1 ATOM 2586 N N . PHE A 1 388 ? -42.449 -7.834 -40.806 1.00 47.63 ? 388 PHE A N 1 ATOM 2587 C CA . PHE A 1 388 ? -41.496 -7.966 -39.711 1.00 42.60 ? 388 PHE A CA 1 ATOM 2588 C C . PHE A 1 388 ? -40.302 -8.813 -40.125 1.00 48.89 ? 388 PHE A C 1 ATOM 2589 O O . PHE A 1 388 ? -40.231 -9.289 -41.257 1.00 56.04 ? 388 PHE A O 1 ATOM 2590 C CB . PHE A 1 388 ? -42.174 -8.604 -38.499 1.00 39.10 ? 388 PHE A CB 1 ATOM 2591 C CG . PHE A 1 388 ? -42.801 -7.617 -37.564 1.00 35.61 ? 388 PHE A CG 1 ATOM 2592 C CD1 . PHE A 1 388 ? -42.123 -6.470 -37.190 1.00 39.37 ? 388 PHE A CD1 1 ATOM 2593 C CD2 . PHE A 1 388 ? -44.069 -7.834 -37.057 1.00 33.00 ? 388 PHE A CD2 1 ATOM 2594 C CE1 . PHE A 1 388 ? -42.696 -5.562 -36.322 1.00 35.98 ? 388 PHE A CE1 1 ATOM 2595 C CE2 . PHE A 1 388 ? -44.649 -6.924 -36.196 1.00 30.70 ? 388 PHE A CE2 1 ATOM 2596 C CZ . PHE A 1 388 ? -43.962 -5.788 -35.828 1.00 28.30 ? 388 PHE A CZ 1 ATOM 2597 N N . LEU A 1 389 ? -39.369 -8.997 -39.197 1.00 44.94 ? 389 LEU A N 1 ATOM 2598 C CA . LEU A 1 389 ? -38.214 -9.857 -39.418 1.00 42.07 ? 389 LEU A CA 1 ATOM 2599 C C . LEU A 1 389 ? -38.000 -10.753 -38.207 1.00 43.93 ? 389 LEU A C 1 ATOM 2600 O O . LEU A 1 389 ? -38.196 -10.320 -37.072 1.00 46.85 ? 389 LEU A O 1 ATOM 2601 C CB . LEU A 1 389 ? -36.968 -9.018 -39.693 1.00 39.19 ? 389 LEU A CB 1 ATOM 2602 C CG . LEU A 1 389 ? -36.802 -8.587 -41.149 1.00 42.02 ? 389 LEU A CG 1 ATOM 2603 C CD1 . LEU A 1 389 ? -36.142 -7.222 -41.251 1.00 45.01 ? 389 LEU A CD1 1 ATOM 2604 C CD2 . LEU A 1 389 ? -35.998 -9.631 -41.903 1.00 46.33 ? 389 LEU A CD2 1 ATOM 2605 N N . LEU A 1 390 ? -37.607 -12.001 -38.447 1.00 46.24 ? 390 LEU A N 1 ATOM 2606 C CA . LEU A 1 390 ? -37.406 -12.953 -37.358 1.00 51.50 ? 390 LEU A CA 1 ATOM 2607 C C . LEU A 1 390 ? -36.293 -12.505 -36.415 1.00 50.55 ? 390 LEU A C 1 ATOM 2608 O O . LEU A 1 390 ? -36.426 -12.618 -35.197 1.00 48.22 ? 390 LEU A O 1 ATOM 2609 C CB . LEU A 1 390 ? -37.120 -14.358 -37.901 1.00 55.34 ? 390 LEU A CB 1 ATOM 2610 C CG . LEU A 1 390 ? -36.819 -15.449 -36.867 1.00 60.27 ? 390 LEU A CG 1 ATOM 2611 C CD1 . LEU A 1 390 ? -37.906 -15.515 -35.805 1.00 47.69 ? 390 LEU A CD1 1 ATOM 2612 C CD2 . LEU A 1 390 ? -36.642 -16.808 -37.537 1.00 69.12 ? 390 LEU A CD2 1 ATOM 2613 N N . ASP A 1 391 ? -35.207 -11.982 -36.977 1.00 47.93 ? 391 ASP A N 1 ATOM 2614 C CA . ASP A 1 391 ? -34.067 -11.563 -36.167 1.00 47.72 ? 391 ASP A CA 1 ATOM 2615 C C . ASP A 1 391 ? -34.326 -10.237 -35.450 1.00 44.54 ? 391 ASP A C 1 ATOM 2616 O O . ASP A 1 391 ? -33.538 -9.824 -34.603 1.00 44.35 ? 391 ASP A O 1 ATOM 2617 C CB . ASP A 1 391 ? -32.791 -11.487 -37.013 1.00 56.93 ? 391 ASP A CB 1 ATOM 2618 C CG . ASP A 1 391 ? -31.559 -11.966 -36.259 1.00 70.24 ? 391 ASP A CG 1 ATOM 2619 O OD1 . ASP A 1 391 ? -31.716 -12.727 -35.280 1.00 63.85 ? 391 ASP A OD1 1 ATOM 2620 O OD2 . ASP A 1 391 ? -30.434 -11.590 -36.649 1.00 76.67 ? 391 ASP A OD2 1 ATOM 2621 N N . GLU A 1 392 ? -35.425 -9.572 -35.800 1.00 45.88 ? 392 GLU A N 1 ATOM 2622 C CA . GLU A 1 392 ? -35.875 -8.391 -35.066 1.00 45.65 ? 392 GLU A CA 1 ATOM 2623 C C . GLU A 1 392 ? -36.616 -8.795 -33.789 1.00 42.98 ? 392 GLU A C 1 ATOM 2624 O O . GLU A 1 392 ? -36.509 -8.127 -32.761 1.00 42.35 ? 392 GLU A O 1 ATOM 2625 C CB . GLU A 1 392 ? -36.769 -7.498 -35.941 1.00 52.07 ? 392 GLU A CB 1 ATOM 2626 C CG . GLU A 1 392 ? -36.027 -6.656 -36.984 1.00 53.96 ? 392 GLU A CG 1 ATOM 2627 C CD . GLU A 1 392 ? -36.946 -5.698 -37.735 1.00 51.84 ? 392 GLU A CD 1 ATOM 2628 O OE1 . GLU A 1 392 ? -38.166 -5.964 -37.801 1.00 44.38 ? 392 GLU A OE1 1 ATOM 2629 O OE2 . GLU A 1 392 ? -36.448 -4.677 -38.258 1.00 48.37 ? 392 GLU A OE2 1 ATOM 2630 N N . ILE A 1 393 ? -37.370 -9.889 -33.867 1.00 42.11 ? 393 ILE A N 1 ATOM 2631 C CA . ILE A 1 393 ? -38.153 -10.385 -32.734 1.00 37.74 ? 393 ILE A CA 1 ATOM 2632 C C . ILE A 1 393 ? -37.292 -11.151 -31.721 1.00 40.99 ? 393 ILE A C 1 ATOM 2633 O O . ILE A 1 393 ? -37.485 -11.019 -30.513 1.00 39.40 ? 393 ILE A O 1 ATOM 2634 C CB . ILE A 1 393 ? -39.361 -11.239 -33.210 1.00 36.27 ? 393 ILE A CB 1 ATOM 2635 C CG1 . ILE A 1 393 ? -40.664 -10.467 -33.023 1.00 36.04 ? 393 ILE A CG1 1 ATOM 2636 C CG2 . ILE A 1 393 ? -39.454 -12.547 -32.450 1.00 39.42 ? 393 ILE A CG2 1 ATOM 2637 C CD1 . ILE A 1 393 ? -40.636 -9.077 -33.598 1.00 38.51 ? 393 ILE A CD1 1 ATOM 2638 N N . VAL A 1 394 ? -36.338 -11.938 -32.214 1.00 45.83 ? 394 VAL A N 1 ATOM 2639 C CA . VAL A 1 394 ? -35.406 -12.653 -31.345 1.00 42.54 ? 394 VAL A CA 1 ATOM 2640 C C . VAL A 1 394 ? -34.524 -11.677 -30.563 1.00 42.93 ? 394 VAL A C 1 ATOM 2641 O O . VAL A 1 394 ? -34.234 -11.896 -29.386 1.00 43.35 ? 394 VAL A O 1 ATOM 2642 C CB . VAL A 1 394 ? -34.539 -13.663 -32.149 1.00 45.47 ? 394 VAL A CB 1 ATOM 2643 C CG1 . VAL A 1 394 ? -33.076 -13.611 -31.721 1.00 41.53 ? 394 VAL A CG1 1 ATOM 2644 C CG2 . VAL A 1 394 ? -35.090 -15.071 -32.007 1.00 47.97 ? 394 VAL A CG2 1 ATOM 2645 N N . ASP A 1 395 ? -34.127 -10.592 -31.222 1.00 42.81 ? 395 ASP A N 1 ATOM 2646 C CA . ASP A 1 395 ? -33.240 -9.596 -30.628 1.00 41.29 ? 395 ASP A CA 1 ATOM 2647 C C . ASP A 1 395 ? -33.846 -8.955 -29.381 1.00 39.36 ? 395 ASP A C 1 ATOM 2648 O O . ASP A 1 395 ? -33.226 -8.943 -28.319 1.00 40.62 ? 395 ASP A O 1 ATOM 2649 C CB . ASP A 1 395 ? -32.895 -8.516 -31.658 1.00 40.73 ? 395 ASP A CB 1 ATOM 2650 C CG . ASP A 1 395 ? -31.426 -8.136 -31.640 1.00 41.04 ? 395 ASP A CG 1 ATOM 2651 O OD1 . ASP A 1 395 ? -30.577 -9.037 -31.478 1.00 43.89 ? 395 ASP A OD1 1 ATOM 2652 O OD2 . ASP A 1 395 ? -31.118 -6.935 -31.792 1.00 40.21 ? 395 ASP A OD2 1 ATOM 2653 N N . VAL A 1 396 ? -35.066 -8.440 -29.510 1.00 37.51 ? 396 VAL A N 1 ATOM 2654 C CA . VAL A 1 396 ? -35.726 -7.749 -28.404 1.00 41.87 ? 396 VAL A CA 1 ATOM 2655 C C . VAL A 1 396 ? -35.977 -8.657 -27.196 1.00 48.57 ? 396 VAL A C 1 ATOM 2656 O O . VAL A 1 396 ? -36.251 -8.174 -26.099 1.00 45.53 ? 396 VAL A O 1 ATOM 2657 C CB . VAL A 1 396 ? -37.048 -7.083 -28.845 1.00 36.24 ? 396 VAL A CB 1 ATOM 2658 C CG1 . VAL A 1 396 ? -36.785 -6.059 -29.935 1.00 34.30 ? 396 VAL A CG1 1 ATOM 2659 C CG2 . VAL A 1 396 ? -38.043 -8.124 -29.324 1.00 35.14 ? 396 VAL A CG2 1 ATOM 2660 N N . GLN A 1 397 ? -35.891 -9.969 -27.404 1.00 52.07 ? 397 GLN A N 1 ATOM 2661 C CA . GLN A 1 397 ? -35.991 -10.928 -26.309 1.00 49.22 ? 397 GLN A CA 1 ATOM 2662 C C . GLN A 1 397 ? -34.674 -10.966 -25.541 1.00 44.70 ? 397 GLN A C 1 ATOM 2663 O O . GLN A 1 397 ? -34.663 -10.982 -24.309 1.00 48.74 ? 397 GLN A O 1 ATOM 2664 C CB . GLN A 1 397 ? -36.326 -12.326 -26.838 1.00 53.13 ? 397 GLN A CB 1 ATOM 2665 C CG . GLN A 1 397 ? -37.588 -12.403 -27.689 1.00 46.93 ? 397 GLN A CG 1 ATOM 2666 C CD . GLN A 1 397 ? -38.844 -12.085 -26.909 1.00 37.19 ? 397 GLN A CD 1 ATOM 2667 O OE1 . GLN A 1 397 ? -39.491 -11.065 -27.141 1.00 30.11 ? 397 GLN A OE1 1 ATOM 2668 N NE2 . GLN A 1 397 ? -39.201 -12.963 -25.981 1.00 45.29 ? 397 GLN A NE2 1 ATOM 2669 N N . TYR A 1 398 ? -33.569 -10.981 -26.283 1.00 38.55 ? 398 TYR A N 1 ATOM 2670 C CA . TYR A 1 398 ? -32.230 -10.967 -25.699 1.00 40.24 ? 398 TYR A CA 1 ATOM 2671 C C . TYR A 1 398 ? -31.864 -9.593 -25.147 1.00 40.95 ? 398 TYR A C 1 ATOM 2672 O O . TYR A 1 398 ? -31.247 -9.489 -24.087 1.00 40.20 ? 398 TYR A O 1 ATOM 2673 C CB . TYR A 1 398 ? -31.188 -11.414 -26.733 1.00 43.71 ? 398 TYR A CB 1 ATOM 2674 C CG . TYR A 1 398 ? -29.963 -10.521 -26.816 1.00 41.58 ? 398 TYR A CG 1 ATOM 2675 C CD1 . TYR A 1 398 ? -28.909 -10.665 -25.923 1.00 42.28 ? 398 TYR A CD1 1 ATOM 2676 C CD2 . TYR A 1 398 ? -29.858 -9.545 -27.798 1.00 39.54 ? 398 TYR A CD2 1 ATOM 2677 C CE1 . TYR A 1 398 ? -27.795 -9.853 -25.998 1.00 43.32 ? 398 TYR A CE1 1 ATOM 2678 C CE2 . TYR A 1 398 ? -28.746 -8.730 -27.880 1.00 38.09 ? 398 TYR A CE2 1 ATOM 2679 C CZ . TYR A 1 398 ? -27.718 -8.889 -26.979 1.00 41.39 ? 398 TYR A CZ 1 ATOM 2680 O OH . TYR A 1 398 ? -26.607 -8.082 -27.056 1.00 46.31 ? 398 TYR A OH 1 ATOM 2681 N N . GLN A 1 399 ? -32.232 -8.545 -25.877 1.00 40.81 ? 399 GLN A N 1 ATOM 2682 C CA . GLN A 1 399 ? -31.928 -7.179 -25.467 1.00 37.99 ? 399 GLN A CA 1 ATOM 2683 C C . GLN A 1 399 ? -32.694 -6.802 -24.205 1.00 37.63 ? 399 GLN A C 1 ATOM 2684 O O . GLN A 1 399 ? -32.254 -5.950 -23.437 1.00 37.36 ? 399 GLN A O 1 ATOM 2685 C CB . GLN A 1 399 ? -32.257 -6.190 -26.591 1.00 37.20 ? 399 GLN A CB 1 ATOM 2686 C CG . GLN A 1 399 ? -31.414 -6.350 -27.850 1.00 38.10 ? 399 GLN A CG 1 ATOM 2687 C CD . GLN A 1 399 ? -30.259 -5.370 -27.914 1.00 36.39 ? 399 GLN A CD 1 ATOM 2688 O OE1 . GLN A 1 399 ? -30.201 -4.407 -27.149 1.00 33.32 ? 399 GLN A OE1 1 ATOM 2689 N NE2 . GLN A 1 399 ? -29.333 -5.608 -28.836 1.00 42.01 ? 399 GLN A NE2 1 ATOM 2690 N N . LEU A 1 400 ? -33.843 -7.437 -23.993 1.00 37.60 ? 400 LEU A N 1 ATOM 2691 C CA . LEU A 1 400 ? -34.668 -7.141 -22.826 1.00 35.75 ? 400 LEU A CA 1 ATOM 2692 C C . LEU A 1 400 ? -34.137 -7.829 -21.573 1.00 35.40 ? 400 LEU A C 1 ATOM 2693 O O . LEU A 1 400 ? -34.462 -7.435 -20.457 1.00 37.98 ? 400 LEU A O 1 ATOM 2694 C CB . LEU A 1 400 ? -36.124 -7.536 -23.075 1.00 34.94 ? 400 LEU A CB 1 ATOM 2695 C CG . LEU A 1 400 ? -37.154 -6.414 -22.933 1.00 32.61 ? 400 LEU A CG 1 ATOM 2696 C CD1 . LEU A 1 400 ? -36.747 -5.213 -23.760 1.00 28.85 ? 400 LEU A CD1 1 ATOM 2697 C CD2 . LEU A 1 400 ? -38.521 -6.898 -23.356 1.00 35.93 ? 400 LEU A CD2 1 ATOM 2698 N N . LYS A 1 401 ? -33.326 -8.864 -21.765 1.00 32.91 ? 401 LYS A N 1 ATOM 2699 C CA . LYS A 1 401 ? -32.654 -9.524 -20.654 1.00 34.71 ? 401 LYS A CA 1 ATOM 2700 C C . LYS A 1 401 ? -31.382 -8.776 -20.278 1.00 39.66 ? 401 LYS A C 1 ATOM 2701 O O . LYS A 1 401 ? -31.264 -8.236 -19.178 1.00 39.90 ? 401 LYS A O 1 ATOM 2702 C CB . LYS A 1 401 ? -32.292 -10.963 -21.021 1.00 36.17 ? 401 LYS A CB 1 ATOM 2703 C CG . LYS A 1 401 ? -33.440 -11.951 -20.980 1.00 36.21 ? 401 LYS A CG 1 ATOM 2704 C CD . LYS A 1 401 ? -32.916 -13.365 -21.179 1.00 44.24 ? 401 LYS A CD 1 ATOM 2705 C CE . LYS A 1 401 ? -34.011 -14.405 -21.018 1.00 55.61 ? 401 LYS A CE 1 ATOM 2706 N NZ . LYS A 1 401 ? -33.484 -15.791 -21.177 1.00 59.10 ? 401 LYS A NZ 1 ATOM 2707 N N . PHE A 1 402 ? -30.436 -8.761 -21.212 1.00 43.43 ? 402 PHE A N 1 ATOM 2708 C CA . PHE A 1 402 ? -29.104 -8.210 -20.987 1.00 40.40 ? 402 PHE A CA 1 ATOM 2709 C C . PHE A 1 402 ? -29.117 -6.738 -20.575 1.00 39.75 ? 402 PHE A C 1 ATOM 2710 O O . PHE A 1 402 ? -28.393 -6.344 -19.664 1.00 46.30 ? 402 PHE A O 1 ATOM 2711 C CB . PHE A 1 402 ? -28.235 -8.415 -22.234 1.00 40.36 ? 402 PHE A CB 1 ATOM 2712 C CG . PHE A 1 402 ? -26.826 -7.925 -22.081 1.00 39.94 ? 402 PHE A CG 1 ATOM 2713 C CD1 . PHE A 1 402 ? -25.966 -8.520 -21.173 1.00 44.32 ? 402 PHE A CD1 1 ATOM 2714 C CD2 . PHE A 1 402 ? -26.358 -6.878 -22.856 1.00 39.47 ? 402 PHE A CD2 1 ATOM 2715 C CE1 . PHE A 1 402 ? -24.665 -8.070 -21.031 1.00 49.64 ? 402 PHE A CE1 1 ATOM 2716 C CE2 . PHE A 1 402 ? -25.059 -6.424 -22.722 1.00 44.76 ? 402 PHE A CE2 1 ATOM 2717 C CZ . PHE A 1 402 ? -24.210 -7.022 -21.809 1.00 50.28 ? 402 PHE A CZ 1 ATOM 2718 N N . LEU A 1 403 ? -29.940 -5.929 -21.233 1.00 36.30 ? 403 LEU A N 1 ATOM 2719 C CA . LEU A 1 403 ? -29.994 -4.502 -20.919 1.00 33.79 ? 403 LEU A CA 1 ATOM 2720 C C . LEU A 1 403 ? -30.742 -4.199 -19.622 1.00 37.58 ? 403 LEU A C 1 ATOM 2721 O O . LEU A 1 403 ? -30.502 -3.171 -18.995 1.00 38.63 ? 403 LEU A O 1 ATOM 2722 C CB . LEU A 1 403 ? -30.580 -3.695 -22.081 1.00 32.86 ? 403 LEU A CB 1 ATOM 2723 C CG . LEU A 1 403 ? -29.591 -3.258 -23.161 1.00 34.49 ? 403 LEU A CG 1 ATOM 2724 C CD1 . LEU A 1 403 ? -30.276 -2.404 -24.213 1.00 38.48 ? 403 LEU A CD1 1 ATOM 2725 C CD2 . LEU A 1 403 ? -28.447 -2.500 -22.525 1.00 38.00 ? 403 LEU A CD2 1 ATOM 2726 N N . ASN A 1 404 ? -31.648 -5.091 -19.227 1.00 38.07 ? 404 ASN A N 1 ATOM 2727 C CA . ASN A 1 404 ? -32.376 -4.940 -17.968 1.00 37.88 ? 404 ASN A CA 1 ATOM 2728 C C . ASN A 1 404 ? -31.482 -5.285 -16.787 1.00 43.17 ? 404 ASN A C 1 ATOM 2729 O O . ASN A 1 404 ? -31.524 -4.626 -15.749 1.00 44.14 ? 404 ASN A O 1 ATOM 2730 C CB . ASN A 1 404 ? -33.623 -5.827 -17.956 1.00 36.60 ? 404 ASN A CB 1 ATOM 2731 C CG . ASN A 1 404 ? -34.413 -5.714 -16.666 1.00 38.85 ? 404 ASN A CG 1 ATOM 2732 O OD1 . ASN A 1 404 ? -34.418 -4.669 -16.015 1.00 39.84 ? 404 ASN A OD1 1 ATOM 2733 N ND2 . ASN A 1 404 ? -35.089 -6.794 -16.291 1.00 40.74 ? 404 ASN A ND2 1 ATOM 2734 N N . TYR A 1 405 ? -30.678 -6.331 -16.958 1.00 44.57 ? 405 TYR A N 1 ATOM 2735 C CA . TYR A 1 405 ? -29.699 -6.736 -15.958 1.00 42.26 ? 405 TYR A CA 1 ATOM 2736 C C . TYR A 1 405 ? -28.772 -5.574 -15.612 1.00 41.16 ? 405 TYR A C 1 ATOM 2737 O O . TYR A 1 405 ? -28.628 -5.212 -14.448 1.00 50.07 ? 405 TYR A O 1 ATOM 2738 C CB . TYR A 1 405 ? -28.899 -7.938 -16.468 1.00 43.63 ? 405 TYR A CB 1 ATOM 2739 C CG . TYR A 1 405 ? -27.706 -8.301 -15.620 1.00 51.46 ? 405 TYR A CG 1 ATOM 2740 C CD1 . TYR A 1 405 ? -27.863 -8.967 -14.411 1.00 57.80 ? 405 TYR A CD1 1 ATOM 2741 C CD2 . TYR A 1 405 ? -26.418 -7.992 -16.036 1.00 56.83 ? 405 TYR A CD2 1 ATOM 2742 C CE1 . TYR A 1 405 ? -26.770 -9.303 -13.635 1.00 62.28 ? 405 TYR A CE1 1 ATOM 2743 C CE2 . TYR A 1 405 ? -25.322 -8.325 -15.269 1.00 73.78 ? 405 TYR A CE2 1 ATOM 2744 C CZ . TYR A 1 405 ? -25.503 -8.981 -14.071 1.00 79.01 ? 405 TYR A CZ 1 ATOM 2745 O OH . TYR A 1 405 ? -24.406 -9.310 -13.310 1.00 79.95 ? 405 TYR A OH 1 ATOM 2746 N N . ILE A 1 406 ? -28.161 -4.983 -16.634 1.00 36.95 ? 406 ILE A N 1 ATOM 2747 C CA . ILE A 1 406 ? -27.297 -3.821 -16.456 1.00 37.79 ? 406 ILE A CA 1 ATOM 2748 C C . ILE A 1 406 ? -28.090 -2.590 -15.996 1.00 40.39 ? 406 ILE A C 1 ATOM 2749 O O . ILE A 1 406 ? -27.560 -1.727 -15.295 1.00 46.99 ? 406 ILE A O 1 ATOM 2750 C CB . ILE A 1 406 ? -26.520 -3.508 -17.757 1.00 37.47 ? 406 ILE A CB 1 ATOM 2751 C CG1 . ILE A 1 406 ? -25.685 -4.716 -18.180 1.00 44.40 ? 406 ILE A CG1 1 ATOM 2752 C CG2 . ILE A 1 406 ? -25.612 -2.306 -17.585 1.00 36.31 ? 406 ILE A CG2 1 ATOM 2753 C CD1 . ILE A 1 406 ? -24.905 -4.491 -19.453 1.00 49.48 ? 406 ILE A CD1 1 ATOM 2754 N N . LEU A 1 407 ? -29.363 -2.517 -16.379 1.00 40.31 ? 407 LEU A N 1 ATOM 2755 C CA . LEU A 1 407 ? -30.215 -1.395 -15.984 1.00 42.13 ? 407 LEU A CA 1 ATOM 2756 C C . LEU A 1 407 ? -30.374 -1.312 -14.472 1.00 45.28 ? 407 LEU A C 1 ATOM 2757 O O . LEU A 1 407 ? -30.083 -0.284 -13.863 1.00 48.20 ? 407 LEU A O 1 ATOM 2758 C CB . LEU A 1 407 ? -31.597 -1.496 -16.638 1.00 40.90 ? 407 LEU A CB 1 ATOM 2759 C CG . LEU A 1 407 ? -32.601 -0.402 -16.267 1.00 39.37 ? 407 LEU A CG 1 ATOM 2760 C CD1 . LEU A 1 407 ? -32.057 0.968 -16.630 1.00 39.10 ? 407 LEU A CD1 1 ATOM 2761 C CD2 . LEU A 1 407 ? -33.947 -0.638 -16.939 1.00 41.26 ? 407 LEU A CD2 1 ATOM 2762 N N . MET A 1 408 ? -30.842 -2.402 -13.875 1.00 45.51 ? 408 MET A N 1 ATOM 2763 C CA . MET A 1 408 ? -31.133 -2.434 -12.448 1.00 46.40 ? 408 MET A CA 1 ATOM 2764 C C . MET A 1 408 ? -29.886 -2.591 -11.575 1.00 47.38 ? 408 MET A C 1 ATOM 2765 O O . MET A 1 408 ? -29.721 -1.876 -10.589 1.00 53.01 ? 408 MET A O 1 ATOM 2766 C CB . MET A 1 408 ? -32.147 -3.542 -12.140 1.00 46.51 ? 408 MET A CB 1 ATOM 2767 C CG . MET A 1 408 ? -33.446 -3.434 -12.928 1.00 51.24 ? 408 MET A CG 1 ATOM 2768 S SD . MET A 1 408 ? -34.320 -1.881 -12.645 1.00 43.14 ? 408 MET A SD 1 ATOM 2769 C CE . MET A 1 408 ? -35.816 -2.151 -13.589 1.00 40.60 ? 408 MET A CE 1 ATOM 2770 N N . ARG A 1 409 ? -29.011 -3.523 -11.941 1.00 46.62 ? 409 ARG A N 1 ATOM 2771 C CA . ARG A 1 409 ? -27.825 -3.819 -11.138 1.00 50.26 ? 409 ARG A CA 1 ATOM 2772 C C . ARG A 1 409 ? -26.859 -2.638 -10.993 1.00 47.00 ? 409 ARG A C 1 ATOM 2773 O O . ARG A 1 409 ? -26.593 -2.180 -9.883 1.00 52.13 ? 409 ARG A O 1 ATOM 2774 C CB . ARG A 1 409 ? -27.096 -5.038 -11.715 1.00 48.63 ? 409 ARG A CB 1 ATOM 2775 C CG . ARG A 1 409 ? -25.700 -5.258 -11.172 1.00 55.00 ? 409 ARG A CG 1 ATOM 2776 C CD . ARG A 1 409 ? -25.110 -6.559 -11.684 1.00 62.33 ? 409 ARG A CD 1 ATOM 2777 N NE . ARG A 1 409 ? -23.719 -6.714 -11.270 1.00 67.56 ? 409 ARG A NE 1 ATOM 2778 C CZ . ARG A 1 409 ? -22.677 -6.392 -12.027 1.00 63.32 ? 409 ARG A CZ 1 ATOM 2779 N NH1 . ARG A 1 409 ? -22.867 -5.906 -13.245 1.00 64.54 ? 409 ARG A NH1 1 ATOM 2780 N NH2 . ARG A 1 409 ? -21.446 -6.560 -11.569 1.00 66.91 ? 409 ARG A NH2 1 ATOM 2781 N N . ILE A 1 410 ? -26.340 -2.149 -12.114 1.00 41.41 ? 410 ILE A N 1 ATOM 2782 C CA . ILE A 1 410 ? -25.376 -1.052 -12.096 1.00 42.89 ? 410 ILE A CA 1 ATOM 2783 C C . ILE A 1 410 ? -26.015 0.334 -11.949 1.00 46.37 ? 410 ILE A C 1 ATOM 2784 O O . ILE A 1 410 ? -25.583 1.142 -11.128 1.00 53.06 ? 410 ILE A O 1 ATOM 2785 C CB . ILE A 1 410 ? -24.471 -1.100 -13.340 1.00 46.10 ? 410 ILE A CB 1 ATOM 2786 C CG1 . ILE A 1 410 ? -23.711 -2.428 -13.372 1.00 49.33 ? 410 ILE A CG1 1 ATOM 2787 C CG2 . ILE A 1 410 ? -23.512 0.079 -13.357 1.00 52.31 ? 410 ILE A CG2 1 ATOM 2788 C CD1 . ILE A 1 410 ? -22.887 -2.637 -14.614 1.00 55.16 ? 410 ILE A CD1 1 ATOM 2789 N N . GLY A 1 411 ? -27.044 0.604 -12.746 1.00 50.02 ? 411 GLY A N 1 ATOM 2790 C CA . GLY A 1 411 ? -27.707 1.896 -12.719 1.00 56.99 ? 411 GLY A CA 1 ATOM 2791 C C . GLY A 1 411 ? -28.568 2.147 -11.495 1.00 56.27 ? 411 GLY A C 1 ATOM 2792 O O . GLY A 1 411 ? -28.422 3.164 -10.817 1.00 62.80 ? 411 GLY A O 1 ATOM 2793 N N . ALA A 1 412 ? -29.480 1.224 -11.214 1.00 49.42 ? 412 ALA A N 1 ATOM 2794 C CA . ALA A 1 412 ? -30.381 1.375 -10.079 1.00 50.11 ? 412 ALA A CA 1 ATOM 2795 C C . ALA A 1 412 ? -29.700 0.984 -8.771 1.00 55.14 ? 412 ALA A C 1 ATOM 2796 O O . ALA A 1 412 ? -29.907 1.620 -7.739 1.00 59.24 ? 412 ALA A O 1 ATOM 2797 C CB . ALA A 1 412 ? -31.647 0.567 -10.292 1.00 49.70 ? 412 ALA A CB 1 ATOM 2798 N N . GLY A 1 413 ? -28.888 -0.067 -8.818 1.00 51.91 ? 413 GLY A N 1 ATOM 2799 C CA . GLY A 1 413 ? -28.133 -0.488 -7.654 1.00 50.52 ? 413 GLY A CA 1 ATOM 2800 C C . GLY A 1 413 ? -28.759 -1.645 -6.902 1.00 50.96 ? 413 GLY A C 1 ATOM 2801 O O . GLY A 1 413 ? -28.213 -2.108 -5.902 1.00 57.01 ? 413 GLY A O 1 ATOM 2802 N N . ALA A 1 414 ? -29.900 -2.119 -7.390 1.00 53.11 ? 414 ALA A N 1 ATOM 2803 C CA . ALA A 1 414 ? -30.629 -3.195 -6.728 1.00 56.70 ? 414 ALA A CA 1 ATOM 2804 C C . ALA A 1 414 ? -29.833 -4.492 -6.726 1.00 55.24 ? 414 ALA A C 1 ATOM 2805 O O . ALA A 1 414 ? -28.961 -4.696 -7.571 1.00 46.68 ? 414 ALA A O 1 ATOM 2806 C CB . ALA A 1 414 ? -31.971 -3.407 -7.399 1.00 55.54 ? 414 ALA A CB 1 ATOM 2807 N N . HIS A 1 415 ? -30.132 -5.361 -5.765 1.00 63.17 ? 415 HIS A N 1 ATOM 2808 C CA . HIS A 1 415 ? -29.509 -6.676 -5.707 1.00 64.97 ? 415 HIS A CA 1 ATOM 2809 C C . HIS A 1 415 ? -29.844 -7.437 -6.983 1.00 60.22 ? 415 HIS A C 1 ATOM 2810 O O . HIS A 1 415 ? -31.016 -7.601 -7.320 1.00 64.57 ? 415 HIS A O 1 ATOM 2811 C CB . HIS A 1 415 ? -29.999 -7.460 -4.485 1.00 72.98 ? 415 HIS A CB 1 ATOM 2812 C CG . HIS A 1 415 ? -29.538 -6.900 -3.173 1.00 78.20 ? 415 HIS A CG 1 ATOM 2813 N ND1 . HIS A 1 415 ? -28.915 -5.676 -3.058 1.00 76.44 ? 415 HIS A ND1 1 ATOM 2814 C CD2 . HIS A 1 415 ? -29.611 -7.403 -1.917 1.00 77.73 ? 415 HIS A CD2 1 ATOM 2815 C CE1 . HIS A 1 415 ? -28.626 -5.448 -1.789 1.00 72.50 ? 415 HIS A CE1 1 ATOM 2816 N NE2 . HIS A 1 415 ? -29.037 -6.480 -1.076 1.00 73.37 ? 415 HIS A NE2 1 ATOM 2817 N N . PRO A 1 416 ? -28.810 -7.902 -7.703 1.00 57.86 ? 416 PRO A N 1 ATOM 2818 C CA . PRO A 1 416 ? -28.972 -8.638 -8.964 1.00 61.21 ? 416 PRO A CA 1 ATOM 2819 C C . PRO A 1 416 ? -29.798 -9.909 -8.791 1.00 66.07 ? 416 PRO A C 1 ATOM 2820 O O . PRO A 1 416 ? -30.264 -10.482 -9.776 1.00 68.49 ? 416 PRO A O 1 ATOM 2821 C CB . PRO A 1 416 ? -27.532 -8.994 -9.345 1.00 65.60 ? 416 PRO A CB 1 ATOM 2822 C CG . PRO A 1 416 ? -26.702 -7.949 -8.687 1.00 69.29 ? 416 PRO A CG 1 ATOM 2823 C CD . PRO A 1 416 ? -27.391 -7.657 -7.388 1.00 63.38 ? 416 PRO A CD 1 ATOM 2824 N N . ASN A 1 417 ? -29.958 -10.341 -7.545 1.00 67.30 ? 417 ASN A N 1 ATOM 2825 C CA . ASN A 1 417 ? -30.792 -11.487 -7.208 1.00 73.55 ? 417 ASN A CA 1 ATOM 2826 C C . ASN A 1 417 ? -32.265 -11.266 -7.560 1.00 73.03 ? 417 ASN A C 1 ATOM 2827 O O . ASN A 1 417 ? -32.959 -12.197 -7.969 1.00 76.74 ? 417 ASN A O 1 ATOM 2828 C CB . ASN A 1 417 ? -30.650 -11.796 -5.714 1.00 78.16 ? 417 ASN A CB 1 ATOM 2829 C CG . ASN A 1 417 ? -31.313 -13.100 -5.316 1.00 88.51 ? 417 ASN A CG 1 ATOM 2830 O OD1 . ASN A 1 417 ? -31.590 -13.954 -6.158 1.00 93.14 ? 417 ASN A OD1 1 ATOM 2831 N ND2 . ASN A 1 417 ? -31.563 -13.264 -4.021 1.00 86.12 ? 417 ASN A ND2 1 ATOM 2832 N N . THR A 1 418 ? -32.737 -10.032 -7.403 1.00 66.03 ? 418 THR A N 1 ATOM 2833 C CA . THR A 1 418 ? -34.146 -9.720 -7.636 1.00 65.84 ? 418 THR A CA 1 ATOM 2834 C C . THR A 1 418 ? -34.452 -9.178 -9.033 1.00 66.28 ? 418 THR A C 1 ATOM 2835 O O . THR A 1 418 ? -35.611 -8.907 -9.351 1.00 67.83 ? 418 THR A O 1 ATOM 2836 C CB . THR A 1 418 ? -34.682 -8.719 -6.600 1.00 68.30 ? 418 THR A CB 1 ATOM 2837 O OG1 . THR A 1 418 ? -33.938 -7.498 -6.686 1.00 64.76 ? 418 THR A OG1 1 ATOM 2838 C CG2 . THR A 1 418 ? -34.562 -9.288 -5.196 1.00 79.17 ? 418 THR A CG2 1 ATOM 2839 N N . ILE A 1 419 ? -33.424 -9.011 -9.859 1.00 63.91 ? 419 ILE A N 1 ATOM 2840 C CA . ILE A 1 419 ? -33.625 -8.510 -11.216 1.00 55.66 ? 419 ILE A CA 1 ATOM 2841 C C . ILE A 1 419 ? -34.489 -9.480 -12.016 1.00 57.42 ? 419 ILE A C 1 ATOM 2842 O O . ILE A 1 419 ? -34.187 -10.671 -12.098 1.00 60.40 ? 419 ILE A O 1 ATOM 2843 C CB . ILE A 1 419 ? -32.285 -8.272 -11.949 1.00 48.85 ? 419 ILE A CB 1 ATOM 2844 C CG1 . ILE A 1 419 ? -31.571 -7.055 -11.364 1.00 47.09 ? 419 ILE A CG1 1 ATOM 2845 C CG2 . ILE A 1 419 ? -32.508 -8.062 -13.438 1.00 47.14 ? 419 ILE A CG2 1 ATOM 2846 C CD1 . ILE A 1 419 ? -30.308 -6.679 -12.098 1.00 45.35 ? 419 ILE A CD1 1 ATOM 2847 N N . SER A 1 420 ? -35.571 -8.963 -12.591 1.00 56.38 ? 420 SER A N 1 ATOM 2848 C CA . SER A 1 420 ? -36.452 -9.763 -13.437 1.00 52.19 ? 420 SER A CA 1 ATOM 2849 C C . SER A 1 420 ? -37.191 -8.883 -14.435 1.00 47.70 ? 420 SER A C 1 ATOM 2850 O O . SER A 1 420 ? -37.308 -7.672 -14.245 1.00 44.86 ? 420 SER A O 1 ATOM 2851 C CB . SER A 1 420 ? -37.453 -10.553 -12.590 1.00 55.29 ? 420 SER A CB 1 ATOM 2852 O OG . SER A 1 420 ? -38.252 -9.688 -11.802 1.00 65.82 ? 420 SER A OG 1 ATOM 2853 N N . GLY A 1 421 ? -37.696 -9.500 -15.498 1.00 52.88 ? 421 GLY A N 1 ATOM 2854 C CA . GLY A 1 421 ? -38.405 -8.766 -16.526 1.00 50.91 ? 421 GLY A CA 1 ATOM 2855 C C . GLY A 1 421 ? -39.437 -9.615 -17.239 1.00 45.26 ? 421 GLY A C 1 ATOM 2856 O O . GLY A 1 421 ? -39.334 -10.840 -17.278 1.00 45.21 ? 421 GLY A O 1 ATOM 2857 N N . THR A 1 422 ? -40.438 -8.958 -17.811 1.00 40.73 ? 422 THR A N 1 ATOM 2858 C CA . THR A 1 422 ? -41.516 -9.661 -18.491 1.00 46.16 ? 422 THR A CA 1 ATOM 2859 C C . THR A 1 422 ? -41.949 -8.910 -19.746 1.00 44.13 ? 422 THR A C 1 ATOM 2860 O O . THR A 1 422 ? -42.072 -7.685 -19.738 1.00 39.18 ? 422 THR A O 1 ATOM 2861 C CB . THR A 1 422 ? -42.723 -9.892 -17.552 1.00 62.23 ? 422 THR A CB 1 ATOM 2862 O OG1 . THR A 1 422 ? -42.772 -8.852 -16.567 1.00 57.94 ? 422 THR A OG1 1 ATOM 2863 C CG2 . THR A 1 422 ? -42.597 -11.234 -16.845 1.00 63.95 ? 422 THR A CG2 1 ATOM 2864 N N . SER A 1 423 ? -42.170 -9.652 -20.826 1.00 43.16 ? 423 SER A N 1 ATOM 2865 C CA . SER A 1 423 ? -42.508 -9.045 -22.106 1.00 44.61 ? 423 SER A CA 1 ATOM 2866 C C . SER A 1 423 ? -43.668 -9.753 -22.794 1.00 61.01 ? 423 SER A C 1 ATOM 2867 O O . SER A 1 423 ? -43.602 -10.954 -23.058 1.00 67.45 ? 423 SER A O 1 ATOM 2868 C CB . SER A 1 423 ? -41.292 -9.058 -23.031 1.00 40.63 ? 423 SER A CB 1 ATOM 2869 O OG . SER A 1 423 ? -40.836 -10.383 -23.245 1.00 40.05 ? 423 SER A OG 1 ATOM 2870 N N . ASP A 1 424 ? -44.728 -9.006 -23.087 1.00 61.26 ? 424 ASP A N 1 ATOM 2871 C CA . ASP A 1 424 ? -45.810 -9.524 -23.914 1.00 51.04 ? 424 ASP A CA 1 ATOM 2872 C C . ASP A 1 424 ? -45.972 -8.679 -25.175 1.00 48.08 ? 424 ASP A C 1 ATOM 2873 O O . ASP A 1 424 ? -46.408 -7.529 -25.112 1.00 43.29 ? 424 ASP A O 1 ATOM 2874 C CB . ASP A 1 424 ? -47.126 -9.561 -23.135 1.00 51.29 ? 424 ASP A CB 1 ATOM 2875 C CG . ASP A 1 424 ? -48.187 -10.395 -23.828 1.00 71.18 ? 424 ASP A CG 1 ATOM 2876 O OD1 . ASP A 1 424 ? -47.891 -11.555 -24.189 1.00 73.67 ? 424 ASP A OD1 1 ATOM 2877 O OD2 . ASP A 1 424 ? -49.315 -9.892 -24.019 1.00 84.78 ? 424 ASP A OD2 1 ATOM 2878 N N . LEU A 1 425 ? -45.623 -9.262 -26.318 1.00 45.49 ? 425 LEU A N 1 ATOM 2879 C CA . LEU A 1 425 ? -45.801 -8.611 -27.612 1.00 38.85 ? 425 LEU A CA 1 ATOM 2880 C C . LEU A 1 425 ? -46.769 -9.444 -28.450 1.00 43.02 ? 425 LEU A C 1 ATOM 2881 O O . LEU A 1 425 ? -46.619 -10.661 -28.540 1.00 43.62 ? 425 LEU A O 1 ATOM 2882 C CB . LEU A 1 425 ? -44.455 -8.465 -28.335 1.00 32.93 ? 425 LEU A CB 1 ATOM 2883 C CG . LEU A 1 425 ? -43.430 -7.467 -27.786 1.00 28.12 ? 425 LEU A CG 1 ATOM 2884 C CD1 . LEU A 1 425 ? -42.118 -7.548 -28.550 1.00 22.84 ? 425 LEU A CD1 1 ATOM 2885 C CD2 . LEU A 1 425 ? -43.974 -6.054 -27.844 1.00 29.73 ? 425 LEU A CD2 1 ATOM 2886 N N . ILE A 1 426 ? -47.765 -8.796 -29.054 1.00 41.56 ? 426 ILE A N 1 ATOM 2887 C CA . ILE A 1 426 ? -48.785 -9.513 -29.825 1.00 41.11 ? 426 ILE A CA 1 ATOM 2888 C C . ILE A 1 426 ? -48.252 -10.101 -31.127 1.00 38.70 ? 426 ILE A C 1 ATOM 2889 O O . ILE A 1 426 ? -48.808 -11.068 -31.653 1.00 39.68 ? 426 ILE A O 1 ATOM 2890 C CB . ILE A 1 426 ? -50.015 -8.633 -30.141 1.00 37.89 ? 426 ILE A CB 1 ATOM 2891 C CG1 . ILE A 1 426 ? -49.609 -7.389 -30.937 1.00 32.29 ? 426 ILE A CG1 1 ATOM 2892 C CG2 . ILE A 1 426 ? -50.752 -8.264 -28.862 1.00 50.79 ? 426 ILE A CG2 1 ATOM 2893 C CD1 . ILE A 1 426 ? -50.778 -6.501 -31.318 1.00 38.84 ? 426 ILE A CD1 1 ATOM 2894 N N . PHE A 1 427 ? -47.181 -9.511 -31.648 1.00 36.55 ? 427 PHE A N 1 ATOM 2895 C CA . PHE A 1 427 ? -46.564 -10.001 -32.876 1.00 34.78 ? 427 PHE A CA 1 ATOM 2896 C C . PHE A 1 427 ? -45.403 -10.959 -32.620 1.00 35.01 ? 427 PHE A C 1 ATOM 2897 O O . PHE A 1 427 ? -44.744 -11.413 -33.556 1.00 35.67 ? 427 PHE A O 1 ATOM 2898 C CB . PHE A 1 427 ? -46.132 -8.843 -33.780 1.00 34.23 ? 427 PHE A CB 1 ATOM 2899 C CG . PHE A 1 427 ? -45.363 -7.763 -33.075 1.00 28.85 ? 427 PHE A CG 1 ATOM 2900 C CD1 . PHE A 1 427 ? -44.009 -7.904 -32.829 1.00 28.92 ? 427 PHE A CD1 1 ATOM 2901 C CD2 . PHE A 1 427 ? -45.991 -6.590 -32.688 1.00 28.72 ? 427 PHE A CD2 1 ATOM 2902 C CE1 . PHE A 1 427 ? -43.300 -6.905 -32.191 1.00 31.47 ? 427 PHE A CE1 1 ATOM 2903 C CE2 . PHE A 1 427 ? -45.288 -5.586 -32.053 1.00 26.52 ? 427 PHE A CE2 1 ATOM 2904 C CZ . PHE A 1 427 ? -43.940 -5.744 -31.803 1.00 29.85 ? 427 PHE A CZ 1 ATOM 2905 N N . ALA A 1 428 ? -45.161 -11.263 -31.349 1.00 37.70 ? 428 ALA A N 1 ATOM 2906 C CA . ALA A 1 428 ? -44.143 -12.239 -30.977 1.00 42.01 ? 428 ALA A CA 1 ATOM 2907 C C . ALA A 1 428 ? -44.710 -13.299 -30.037 1.00 47.10 ? 428 ALA A C 1 ATOM 2908 O O . ALA A 1 428 ? -45.295 -12.977 -29.004 1.00 42.16 ? 428 ALA A O 1 ATOM 2909 C CB . ALA A 1 428 ? -42.957 -11.545 -30.334 1.00 42.39 ? 428 ALA A CB 1 ATOM 2910 N N . ASP A 1 429 ? -44.532 -14.565 -30.400 1.00 54.51 ? 429 ASP A N 1 ATOM 2911 C CA . ASP A 1 429 ? -44.976 -15.679 -29.569 1.00 63.06 ? 429 ASP A CA 1 ATOM 2912 C C . ASP A 1 429 ? -43.761 -16.510 -29.171 1.00 70.22 ? 429 ASP A C 1 ATOM 2913 O O . ASP A 1 429 ? -43.488 -17.546 -29.776 1.00 77.29 ? 429 ASP A O 1 ATOM 2914 C CB . ASP A 1 429 ? -45.990 -16.538 -30.332 1.00 61.40 ? 429 ASP A CB 1 ATOM 2915 C CG . ASP A 1 429 ? -46.581 -17.653 -29.482 1.00 65.52 ? 429 ASP A CG 1 ATOM 2916 O OD1 . ASP A 1 429 ? -46.458 -17.594 -28.241 1.00 69.76 ? 429 ASP A OD1 1 ATOM 2917 O OD2 . ASP A 1 429 ? -47.181 -18.584 -30.059 1.00 62.94 ? 429 ASP A OD2 1 ATOM 2918 N N . PRO A 1 430 ? -43.026 -16.051 -28.143 1.00 64.11 ? 430 PRO A N 1 ATOM 2919 C CA . PRO A 1 430 ? -41.747 -16.642 -27.729 1.00 57.81 ? 430 PRO A CA 1 ATOM 2920 C C . PRO A 1 430 ? -41.877 -18.100 -27.302 1.00 60.96 ? 430 PRO A C 1 ATOM 2921 O O . PRO A 1 430 ? -41.032 -18.921 -27.665 1.00 61.55 ? 430 PRO A O 1 ATOM 2922 C CB . PRO A 1 430 ? -41.333 -15.778 -26.529 1.00 54.97 ? 430 PRO A CB 1 ATOM 2923 C CG . PRO A 1 430 ? -42.123 -14.512 -26.666 1.00 55.40 ? 430 PRO A CG 1 ATOM 2924 C CD . PRO A 1 430 ? -43.421 -14.935 -27.267 1.00 59.58 ? 430 PRO A CD 1 ATOM 2925 N N . SER A 1 431 ? -42.925 -18.406 -26.541 1.00 65.64 ? 431 SER A N 1 ATOM 2926 C CA . SER A 1 431 ? -43.169 -19.759 -26.051 1.00 69.54 ? 431 SER A CA 1 ATOM 2927 C C . SER A 1 431 ? -43.183 -20.774 -27.193 1.00 67.44 ? 431 SER A C 1 ATOM 2928 O O . SER A 1 431 ? -42.656 -21.878 -27.062 1.00 66.60 ? 431 SER A O 1 ATOM 2929 C CB . SER A 1 431 ? -44.492 -19.809 -25.281 1.00 67.25 ? 431 SER A CB 1 ATOM 2930 O OG . SER A 1 431 ? -44.984 -18.502 -25.027 1.00 58.07 ? 431 SER A OG 1 ATOM 2931 N N . GLN A 1 432 ? -43.779 -20.383 -28.316 1.00 66.95 ? 432 GLN A N 1 ATOM 2932 C CA . GLN A 1 432 ? -43.813 -21.228 -29.505 1.00 76.42 ? 432 GLN A CA 1 ATOM 2933 C C . GLN A 1 432 ? -42.426 -21.332 -30.136 1.00 75.39 ? 432 GLN A C 1 ATOM 2934 O O . GLN A 1 432 ? -41.954 -22.431 -30.432 1.00 75.41 ? 432 GLN A O 1 ATOM 2935 C CB . GLN A 1 432 ? -44.815 -20.675 -30.525 1.00 77.24 ? 432 GLN A CB 1 ATOM 2936 C CG . GLN A 1 432 ? -44.881 -21.459 -31.830 1.00 75.48 ? 432 GLN A CG 1 ATOM 2937 C CD . GLN A 1 432 ? -45.600 -20.703 -32.933 1.00 71.43 ? 432 GLN A CD 1 ATOM 2938 O OE1 . GLN A 1 432 ? -45.001 -19.887 -33.633 1.00 68.44 ? 432 GLN A OE1 1 ATOM 2939 N NE2 . GLN A 1 432 ? -46.890 -20.976 -33.096 1.00 72.59 ? 432 GLN A NE2 1 ATOM 2940 N N . LEU A 1 433 ? -41.787 -20.182 -30.338 1.00 72.57 ? 433 LEU A N 1 ATOM 2941 C CA . LEU A 1 433 ? -40.432 -20.117 -30.881 1.00 70.71 ? 433 LEU A CA 1 ATOM 2942 C C . LEU A 1 433 ? -39.481 -21.027 -30.109 1.00 75.86 ? 433 LEU A C 1 ATOM 2943 O O . LEU A 1 433 ? -38.631 -21.696 -30.699 1.00 78.45 ? 433 LEU A O 1 ATOM 2944 C CB . LEU A 1 433 ? -39.915 -18.675 -30.858 1.00 61.58 ? 433 LEU A CB 1 ATOM 2945 C CG . LEU A 1 433 ? -40.386 -17.719 -31.954 1.00 54.88 ? 433 LEU A CG 1 ATOM 2946 C CD1 . LEU A 1 433 ? -40.050 -16.283 -31.594 1.00 51.58 ? 433 LEU A CD1 1 ATOM 2947 C CD2 . LEU A 1 433 ? -39.747 -18.087 -33.278 1.00 61.32 ? 433 LEU A CD2 1 ATOM 2948 N N . HIS A 1 434 ? -39.640 -21.051 -28.789 1.00 76.14 ? 434 HIS A N 1 ATOM 2949 C CA . HIS A 1 434 ? -38.836 -21.912 -27.927 1.00 78.18 ? 434 HIS A CA 1 ATOM 2950 C C . HIS A 1 434 ? -39.053 -23.385 -28.262 1.00 81.35 ? 434 HIS A C 1 ATOM 2951 O O . HIS A 1 434 ? -38.098 -24.159 -28.339 1.00 80.45 ? 434 HIS A O 1 ATOM 2952 C CB . HIS A 1 434 ? -39.164 -21.648 -26.454 1.00 73.95 ? 434 HIS A CB 1 ATOM 2953 C CG . HIS A 1 434 ? -38.390 -22.501 -25.499 1.00 66.67 ? 434 HIS A CG 1 ATOM 2954 N ND1 . HIS A 1 434 ? -37.016 -22.599 -25.533 1.00 63.54 ? 434 HIS A ND1 1 ATOM 2955 C CD2 . HIS A 1 434 ? -38.799 -23.296 -24.482 1.00 68.01 ? 434 HIS A CD2 1 ATOM 2956 C CE1 . HIS A 1 434 ? -36.611 -23.418 -24.580 1.00 73.01 ? 434 HIS A CE1 1 ATOM 2957 N NE2 . HIS A 1 434 ? -37.673 -23.856 -23.927 1.00 77.01 ? 434 HIS A NE2 1 ATOM 2958 N N . ASP A 1 435 ? -40.314 -23.764 -28.463 1.00 76.70 ? 435 ASP A N 1 ATOM 2959 C CA . ASP A 1 435 ? -40.660 -25.144 -28.793 1.00 74.68 ? 435 ASP A CA 1 ATOM 2960 C C . ASP A 1 435 ? -40.151 -25.525 -30.179 1.00 76.54 ? 435 ASP A C 1 ATOM 2961 O O . ASP A 1 435 ? -39.755 -26.667 -30.412 1.00 81.18 ? 435 ASP A O 1 ATOM 2962 C CB . ASP A 1 435 ? -42.173 -25.365 -28.706 1.00 73.93 ? 435 ASP A CB 1 ATOM 2963 C CG . ASP A 1 435 ? -42.691 -25.314 -27.281 1.00 79.60 ? 435 ASP A CG 1 ATOM 2964 O OD1 . ASP A 1 435 ? -41.871 -25.403 -26.343 1.00 79.41 ? 435 ASP A OD1 1 ATOM 2965 O OD2 . ASP A 1 435 ? -43.922 -25.197 -27.101 1.00 86.37 ? 435 ASP A OD2 1 ATOM 2966 N N . GLU A 1 436 ? -40.166 -24.563 -31.097 1.00 72.98 ? 436 GLU A N 1 ATOM 2967 C CA . GLU A 1 436 ? -39.628 -24.774 -32.436 1.00 76.28 ? 436 GLU A CA 1 ATOM 2968 C C . GLU A 1 436 ? -38.114 -24.945 -32.372 1.00 77.96 ? 436 GLU A C 1 ATOM 2969 O O . GLU A 1 436 ? -37.515 -25.601 -33.224 1.00 74.61 ? 436 GLU A O 1 ATOM 2970 C CB . GLU A 1 436 ? -39.986 -23.604 -33.358 1.00 75.90 ? 436 GLU A CB 1 ATOM 2971 C CG . GLU A 1 436 ? -41.478 -23.331 -33.478 1.00 77.90 ? 436 GLU A CG 1 ATOM 2972 C CD . GLU A 1 436 ? -41.798 -22.276 -34.522 1.00 78.22 ? 436 GLU A CD 1 ATOM 2973 O OE1 . GLU A 1 436 ? -40.969 -22.068 -35.434 1.00 74.23 ? 436 GLU A OE1 1 ATOM 2974 O OE2 . GLU A 1 436 ? -42.879 -21.657 -34.430 1.00 71.37 ? 436 GLU A OE2 1 ATOM 2975 N N . LEU A 1 437 ? -37.504 -24.337 -31.359 1.00 79.02 ? 437 LEU A N 1 ATOM 2976 C CA . LEU A 1 437 ? -36.071 -24.470 -31.123 1.00 77.34 ? 437 LEU A CA 1 ATOM 2977 C C . LEU A 1 437 ? -35.755 -25.812 -30.472 1.00 77.43 ? 437 LEU A C 1 ATOM 2978 O O . LEU A 1 437 ? -34.804 -26.490 -30.862 1.00 80.51 ? 437 LEU A O 1 ATOM 2979 C CB . LEU A 1 437 ? -35.559 -23.325 -30.245 1.00 70.80 ? 437 LEU A CB 1 ATOM 2980 C CG . LEU A 1 437 ? -34.045 -23.267 -30.036 1.00 61.23 ? 437 LEU A CG 1 ATOM 2981 C CD1 . LEU A 1 437 ? -33.328 -23.035 -31.357 1.00 56.06 ? 437 LEU A CD1 1 ATOM 2982 C CD2 . LEU A 1 437 ? -33.673 -22.193 -29.029 1.00 58.90 ? 437 LEU A CD2 1 ATOM 2983 N N . SER A 1 438 ? -36.565 -26.183 -29.483 1.00 70.45 ? 438 SER A N 1 ATOM 2984 C CA . SER A 1 438 ? -36.391 -27.430 -28.738 1.00 73.83 ? 438 SER A CA 1 ATOM 2985 C C . SER A 1 438 ? -36.337 -28.658 -29.645 1.00 77.59 ? 438 SER A C 1 ATOM 2986 O O . SER A 1 438 ? -35.626 -29.622 -29.358 1.00 77.44 ? 438 SER A O 1 ATOM 2987 C CB . SER A 1 438 ? -37.515 -27.588 -27.709 1.00 77.78 ? 438 SER A CB 1 ATOM 2988 O OG . SER A 1 438 ? -37.394 -28.805 -26.995 1.00 87.38 ? 438 SER A OG 1 ATOM 2989 N N . LEU A 1 439 ? -37.089 -28.614 -30.740 1.00 84.49 ? 439 LEU A N 1 ATOM 2990 C CA . LEU A 1 439 ? -37.106 -29.707 -31.705 1.00 88.17 ? 439 LEU A CA 1 ATOM 2991 C C . LEU A 1 439 ? -36.010 -29.562 -32.764 1.00 87.27 ? 439 LEU A C 1 ATOM 2992 O O . LEU A 1 439 ? -35.719 -30.506 -33.498 1.00 88.07 ? 439 LEU A O 1 ATOM 2993 C CB . LEU A 1 439 ? -38.485 -29.816 -32.362 1.00 74.38 ? 439 LEU A CB 1 ATOM 2994 C CG . LEU A 1 439 ? -39.663 -29.928 -31.388 1.00 74.68 ? 439 LEU A CG 1 ATOM 2995 C CD1 . LEU A 1 439 ? -40.983 -30.074 -32.128 1.00 82.06 ? 439 LEU A CD1 1 ATOM 2996 C CD2 . LEU A 1 439 ? -39.464 -31.081 -30.413 1.00 72.66 ? 439 LEU A CD2 1 ATOM 2997 N N . LEU A 1 440 ? -35.403 -28.379 -32.839 1.00 79.50 ? 440 LEU A N 1 ATOM 2998 C CA . LEU A 1 440 ? -34.313 -28.145 -33.784 1.00 77.73 ? 440 LEU A CA 1 ATOM 2999 C C . LEU A 1 440 ? -33.005 -28.713 -33.243 1.00 81.65 ? 440 LEU A C 1 ATOM 3000 O O . LEU A 1 440 ? -32.232 -29.326 -33.979 1.00 86.74 ? 440 LEU A O 1 ATOM 3001 C CB . LEU A 1 440 ? -34.161 -26.653 -34.098 1.00 75.83 ? 440 LEU A CB 1 ATOM 3002 C CG . LEU A 1 440 ? -34.124 -26.263 -35.582 1.00 80.34 ? 440 LEU A CG 1 ATOM 3003 C CD1 . LEU A 1 440 ? -33.667 -24.820 -35.768 1.00 77.86 ? 440 LEU A CD1 1 ATOM 3004 C CD2 . LEU A 1 440 ? -33.248 -27.212 -36.388 1.00 76.64 ? 440 LEU A CD2 1 ATOM 3005 N N . PHE A 1 441 ? -32.766 -28.504 -31.951 1.00 83.55 ? 441 PHE A N 1 ATOM 3006 C CA . PHE A 1 441 ? -31.599 -29.068 -31.281 1.00 89.51 ? 441 PHE A CA 1 ATOM 3007 C C . PHE A 1 441 ? -31.725 -30.587 -31.186 1.00 92.93 ? 441 PHE A C 1 ATOM 3008 O O . PHE A 1 441 ? -30.734 -31.309 -31.289 1.00 97.87 ? 441 PHE A O 1 ATOM 3009 C CB . PHE A 1 441 ? -31.433 -28.470 -29.878 1.00 80.97 ? 441 PHE A CB 1 ATOM 3010 C CG . PHE A 1 441 ? -30.821 -27.093 -29.860 1.00 76.58 ? 441 PHE A CG 1 ATOM 3011 C CD1 . PHE A 1 441 ? -29.769 -26.769 -30.705 1.00 75.89 ? 441 PHE A CD1 1 ATOM 3012 C CD2 . PHE A 1 441 ? -31.296 -26.123 -28.991 1.00 65.59 ? 441 PHE A CD2 1 ATOM 3013 C CE1 . PHE A 1 441 ? -29.204 -25.502 -30.680 1.00 67.66 ? 441 PHE A CE1 1 ATOM 3014 C CE2 . PHE A 1 441 ? -30.740 -24.856 -28.965 1.00 67.18 ? 441 PHE A CE2 1 ATOM 3015 C CZ . PHE A 1 441 ? -29.693 -24.546 -29.812 1.00 68.92 ? 441 PHE A CZ 1 ATOM 3016 N N . GLY A 1 442 ? -32.950 -31.067 -30.995 1.00 87.31 ? 442 GLY A N 1 ATOM 3017 C CA . GLY A 1 442 ? -33.199 -32.488 -30.833 1.00 86.96 ? 442 GLY A CA 1 ATOM 3018 C C . GLY A 1 442 ? -33.351 -33.250 -32.137 1.00 96.85 ? 442 GLY A C 1 ATOM 3019 O O . GLY A 1 442 ? -33.869 -34.368 -32.149 1.00 104.13 ? 442 GLY A O 1 ATOM 3020 N N . GLN A 1 443 ? -32.906 -32.648 -33.236 1.00 97.62 ? 443 GLN A N 1 ATOM 3021 C CA . GLN A 1 443 ? -32.983 -33.290 -34.544 1.00 92.86 ? 443 GLN A CA 1 ATOM 3022 C C . GLN A 1 443 ? -31.594 -33.550 -35.117 1.00 85.01 ? 443 GLN A C 1 ATOM 3023 O O . GLN A 1 443 ? -30.585 -33.205 -34.504 1.00 77.63 ? 443 GLN A O 1 ATOM 3024 C CB . GLN A 1 443 ? -33.805 -32.443 -35.505 1.00 82.22 ? 443 GLN A CB 1 ATOM 3025 N N . PHE A 1 452 ? -18.643 -30.127 -36.832 1.00 91.36 ? 452 PHE A N 1 ATOM 3026 C CA . PHE A 1 452 ? -18.070 -28.789 -36.939 1.00 97.03 ? 452 PHE A CA 1 ATOM 3027 C C . PHE A 1 452 ? -19.144 -27.715 -37.078 1.00 98.89 ? 452 PHE A C 1 ATOM 3028 O O . PHE A 1 452 ? -20.078 -27.853 -37.867 1.00 111.24 ? 452 PHE A O 1 ATOM 3029 C CB . PHE A 1 452 ? -17.095 -28.712 -38.120 1.00 97.83 ? 452 PHE A CB 1 ATOM 3030 C CG . PHE A 1 452 ? -16.723 -27.307 -38.512 1.00 98.05 ? 452 PHE A CG 1 ATOM 3031 C CD1 . PHE A 1 452 ? -15.791 -26.590 -37.779 1.00 97.93 ? 452 PHE A CD1 1 ATOM 3032 C CD2 . PHE A 1 452 ? -17.303 -26.706 -39.619 1.00 94.41 ? 452 PHE A CD2 1 ATOM 3033 C CE1 . PHE A 1 452 ? -15.448 -25.297 -38.139 1.00 92.38 ? 452 PHE A CE1 1 ATOM 3034 C CE2 . PHE A 1 452 ? -16.965 -25.414 -39.984 1.00 95.03 ? 452 PHE A CE2 1 ATOM 3035 C CZ . PHE A 1 452 ? -16.035 -24.709 -39.242 1.00 93.42 ? 452 PHE A CZ 1 ATOM 3036 N N . ILE A 1 453 ? -19.007 -26.647 -36.297 1.00 90.57 ? 453 ILE A N 1 ATOM 3037 C CA . ILE A 1 453 ? -19.889 -25.489 -36.403 1.00 83.05 ? 453 ILE A CA 1 ATOM 3038 C C . ILE A 1 453 ? -19.060 -24.207 -36.427 1.00 88.08 ? 453 ILE A C 1 ATOM 3039 O O . ILE A 1 453 ? -18.341 -23.913 -35.471 1.00 97.95 ? 453 ILE A O 1 ATOM 3040 C CB . ILE A 1 453 ? -20.889 -25.425 -35.229 1.00 77.31 ? 453 ILE A CB 1 ATOM 3041 C CG1 . ILE A 1 453 ? -21.733 -26.701 -35.169 1.00 81.66 ? 453 ILE A CG1 1 ATOM 3042 C CG2 . ILE A 1 453 ? -21.783 -24.202 -35.362 1.00 82.96 ? 453 ILE A CG2 1 ATOM 3043 C CD1 . ILE A 1 453 ? -22.618 -26.802 -33.945 1.00 80.78 ? 453 ILE A CD1 1 ATOM 3044 N N . SER A 1 454 ? -19.151 -23.451 -37.519 1.00 90.96 ? 454 SER A N 1 ATOM 3045 C CA . SER A 1 454 ? -18.418 -22.192 -37.637 1.00 90.76 ? 454 SER A CA 1 ATOM 3046 C C . SER A 1 454 ? -18.919 -21.202 -36.594 1.00 87.92 ? 454 SER A C 1 ATOM 3047 O O . SER A 1 454 ? -20.071 -21.279 -36.171 1.00 86.81 ? 454 SER A O 1 ATOM 3048 C CB . SER A 1 454 ? -18.555 -21.601 -39.044 1.00 96.36 ? 454 SER A CB 1 ATOM 3049 O OG . SER A 1 454 ? -19.897 -21.242 -39.323 1.00 93.57 ? 454 SER A OG 1 ATOM 3050 N N . TYR A 1 455 ? -18.052 -20.282 -36.179 1.00 86.96 ? 455 TYR A N 1 ATOM 3051 C CA . TYR A 1 455 ? -18.374 -19.351 -35.097 1.00 86.01 ? 455 TYR A CA 1 ATOM 3052 C C . TYR A 1 455 ? -19.600 -18.485 -35.385 1.00 89.80 ? 455 TYR A C 1 ATOM 3053 O O . TYR A 1 455 ? -20.335 -18.116 -34.468 1.00 88.40 ? 455 TYR A O 1 ATOM 3054 C CB . TYR A 1 455 ? -17.167 -18.476 -34.745 1.00 77.83 ? 455 TYR A CB 1 ATOM 3055 C CG . TYR A 1 455 ? -16.208 -19.124 -33.770 1.00 76.05 ? 455 TYR A CG 1 ATOM 3056 C CD1 . TYR A 1 455 ? -16.508 -20.344 -33.179 1.00 75.58 ? 455 TYR A CD1 1 ATOM 3057 C CD2 . TYR A 1 455 ? -15.011 -18.511 -33.430 1.00 71.61 ? 455 TYR A CD2 1 ATOM 3058 C CE1 . TYR A 1 455 ? -15.640 -20.938 -32.286 1.00 69.23 ? 455 TYR A CE1 1 ATOM 3059 C CE2 . TYR A 1 455 ? -14.135 -19.097 -32.536 1.00 67.76 ? 455 TYR A CE2 1 ATOM 3060 C CZ . TYR A 1 455 ? -14.456 -20.311 -31.967 1.00 68.78 ? 455 TYR A CZ 1 ATOM 3061 O OH . TYR A 1 455 ? -13.590 -20.901 -31.077 1.00 73.18 ? 455 TYR A OH 1 ATOM 3062 N N . ASP A 1 456 ? -19.816 -18.165 -36.656 1.00 90.17 ? 456 ASP A N 1 ATOM 3063 C CA . ASP A 1 456 ? -20.997 -17.410 -37.058 1.00 84.56 ? 456 ASP A CA 1 ATOM 3064 C C . ASP A 1 456 ? -22.270 -18.221 -36.816 1.00 82.73 ? 456 ASP A C 1 ATOM 3065 O O . ASP A 1 456 ? -23.236 -17.717 -36.242 1.00 79.87 ? 456 ASP A O 1 ATOM 3066 C CB . ASP A 1 456 ? -20.897 -16.992 -38.528 1.00 87.59 ? 456 ASP A CB 1 ATOM 3067 C CG . ASP A 1 456 ? -19.832 -15.937 -38.765 1.00 92.15 ? 456 ASP A CG 1 ATOM 3068 O OD1 . ASP A 1 456 ? -18.699 -16.302 -39.145 1.00 98.25 ? 456 ASP A OD1 1 ATOM 3069 O OD2 . ASP A 1 456 ? -20.129 -14.739 -38.569 1.00 86.55 ? 456 ASP A OD2 1 ATOM 3070 N N . GLU A 1 457 ? -22.259 -19.479 -37.251 1.00 86.24 ? 457 GLU A N 1 ATOM 3071 C CA . GLU A 1 457 ? -23.405 -20.370 -37.075 1.00 85.81 ? 457 GLU A CA 1 ATOM 3072 C C . GLU A 1 457 ? -23.690 -20.642 -35.601 1.00 75.64 ? 457 GLU A C 1 ATOM 3073 O O . GLU A 1 457 ? -24.845 -20.756 -35.195 1.00 64.17 ? 457 GLU A O 1 ATOM 3074 C CB . GLU A 1 457 ? -23.181 -21.695 -37.813 1.00 92.06 ? 457 GLU A CB 1 ATOM 3075 C CG . GLU A 1 457 ? -23.070 -21.572 -39.327 1.00 95.18 ? 457 GLU A CG 1 ATOM 3076 C CD . GLU A 1 457 ? -22.945 -22.922 -40.013 1.00 96.69 ? 457 GLU A CD 1 ATOM 3077 O OE1 . GLU A 1 457 ? -23.515 -23.907 -39.498 1.00 94.83 ? 457 GLU A OE1 1 ATOM 3078 O OE2 . GLU A 1 457 ? -22.274 -22.999 -41.064 1.00 96.21 ? 457 GLU A OE2 1 ATOM 3079 N N . ALA A 1 458 ? -22.629 -20.745 -34.807 1.00 83.10 ? 458 ALA A N 1 ATOM 3080 C CA . ALA A 1 458 ? -22.757 -21.009 -33.377 1.00 77.54 ? 458 ALA A CA 1 ATOM 3081 C C . ALA A 1 458 ? -23.275 -19.788 -32.616 1.00 71.85 ? 458 ALA A C 1 ATOM 3082 O O . ALA A 1 458 ? -23.980 -19.928 -31.616 1.00 65.96 ? 458 ALA A O 1 ATOM 3083 C CB . ALA A 1 458 ? -21.430 -21.484 -32.800 1.00 71.20 ? 458 ALA A CB 1 ATOM 3084 N N . ARG A 1 459 ? -22.919 -18.595 -33.088 1.00 70.52 ? 459 ARG A N 1 ATOM 3085 C CA . ARG A 1 459 ? -23.415 -17.357 -32.491 1.00 66.81 ? 459 ARG A CA 1 ATOM 3086 C C . ARG A 1 459 ? -24.934 -17.293 -32.576 1.00 68.03 ? 459 ARG A C 1 ATOM 3087 O O . ARG A 1 459 ? -25.613 -17.030 -31.584 1.00 58.54 ? 459 ARG A O 1 ATOM 3088 C CB . ARG A 1 459 ? -22.811 -16.131 -33.186 1.00 61.62 ? 459 ARG A CB 1 ATOM 3089 C CG . ARG A 1 459 ? -23.289 -14.803 -32.610 1.00 60.53 ? 459 ARG A CG 1 ATOM 3090 C CD . ARG A 1 459 ? -23.855 -13.871 -33.676 1.00 63.13 ? 459 ARG A CD 1 ATOM 3091 N NE . ARG A 1 459 ? -22.818 -13.257 -34.502 1.00 69.35 ? 459 ARG A NE 1 ATOM 3092 C CZ . ARG A 1 459 ? -22.561 -13.610 -35.757 1.00 82.14 ? 459 ARG A CZ 1 ATOM 3093 N NH1 . ARG A 1 459 ? -23.269 -14.572 -36.329 1.00 83.05 ? 459 ARG A NH1 1 ATOM 3094 N NH2 . ARG A 1 459 ? -21.600 -13.001 -36.441 1.00 81.31 ? 459 ARG A NH2 1 ATOM 3095 N N . ASP A 1 460 ? -25.457 -17.551 -33.770 1.00 73.91 ? 460 ASP A N 1 ATOM 3096 C CA . ASP A 1 460 ? -26.890 -17.471 -34.028 1.00 66.38 ? 460 ASP A CA 1 ATOM 3097 C C . ASP A 1 460 ? -27.667 -18.539 -33.260 1.00 59.78 ? 460 ASP A C 1 ATOM 3098 O O . ASP A 1 460 ? -28.794 -18.303 -32.827 1.00 56.09 ? 460 ASP A O 1 ATOM 3099 C CB . ASP A 1 460 ? -27.166 -17.597 -35.529 1.00 66.97 ? 460 ASP A CB 1 ATOM 3100 C CG . ASP A 1 460 ? -26.284 -16.685 -36.366 1.00 61.92 ? 460 ASP A CG 1 ATOM 3101 O OD1 . ASP A 1 460 ? -25.800 -15.662 -35.835 1.00 58.65 ? 460 ASP A OD1 1 ATOM 3102 O OD2 . ASP A 1 460 ? -26.078 -16.990 -37.559 1.00 60.97 ? 460 ASP A OD2 1 ATOM 3103 N N . GLN A 1 461 ? -27.063 -19.714 -33.096 1.00 59.55 ? 461 GLN A N 1 ATOM 3104 C CA . GLN A 1 461 ? -27.710 -20.806 -32.374 1.00 56.53 ? 461 GLN A CA 1 ATOM 3105 C C . GLN A 1 461 ? -27.829 -20.499 -30.885 1.00 62.02 ? 461 GLN A C 1 ATOM 3106 O O . GLN A 1 461 ? -28.850 -20.790 -30.269 1.00 62.27 ? 461 GLN A O 1 ATOM 3107 C CB . GLN A 1 461 ? -26.962 -22.131 -32.575 1.00 61.81 ? 461 GLN A CB 1 ATOM 3108 C CG . GLN A 1 461 ? -27.030 -22.702 -33.986 1.00 75.43 ? 461 GLN A CG 1 ATOM 3109 C CD . GLN A 1 461 ? -26.757 -24.198 -34.030 1.00 77.04 ? 461 GLN A CD 1 ATOM 3110 O OE1 . GLN A 1 461 ? -27.091 -24.930 -33.097 1.00 74.46 ? 461 GLN A OE1 1 ATOM 3111 N NE2 . GLN A 1 461 ? -26.149 -24.659 -35.119 1.00 71.46 ? 461 GLN A NE2 1 ATOM 3112 N N . LEU A 1 462 ? -26.778 -19.914 -30.315 1.00 66.65 ? 462 LEU A N 1 ATOM 3113 C CA . LEU A 1 462 ? -26.737 -19.602 -28.886 1.00 63.22 ? 462 LEU A CA 1 ATOM 3114 C C . LEU A 1 462 ? -27.514 -18.334 -28.535 1.00 61.63 ? 462 LEU A C 1 ATOM 3115 O O . LEU A 1 462 ? -28.231 -18.291 -27.534 1.00 58.08 ? 462 LEU A O 1 ATOM 3116 C CB . LEU A 1 462 ? -25.285 -19.474 -28.414 1.00 56.81 ? 462 LEU A CB 1 ATOM 3117 C CG . LEU A 1 462 ? -24.451 -20.758 -28.459 1.00 56.55 ? 462 LEU A CG 1 ATOM 3118 C CD1 . LEU A 1 462 ? -22.995 -20.480 -28.127 1.00 67.25 ? 462 LEU A CD1 1 ATOM 3119 C CD2 . LEU A 1 462 ? -25.025 -21.787 -27.506 1.00 60.36 ? 462 LEU A CD2 1 ATOM 3120 N N . LYS A 1 463 ? -27.357 -17.305 -29.363 1.00 63.23 ? 463 LYS A N 1 ATOM 3121 C CA . LYS A 1 463 ? -28.071 -16.043 -29.194 1.00 58.15 ? 463 LYS A CA 1 ATOM 3122 C C . LYS A 1 463 ? -29.575 -16.282 -29.170 1.00 52.86 ? 463 LYS A C 1 ATOM 3123 O O . LYS A 1 463 ? -30.287 -15.744 -28.324 1.00 46.83 ? 463 LYS A O 1 ATOM 3124 C CB . LYS A 1 463 ? -27.698 -15.086 -30.328 1.00 56.52 ? 463 LYS A CB 1 ATOM 3125 C CG . LYS A 1 463 ? -28.480 -13.787 -30.378 1.00 52.37 ? 463 LYS A CG 1 ATOM 3126 C CD . LYS A 1 463 ? -27.971 -12.924 -31.527 1.00 60.90 ? 463 LYS A CD 1 ATOM 3127 C CE . LYS A 1 463 ? -28.808 -11.670 -31.711 1.00 62.95 ? 463 LYS A CE 1 ATOM 3128 N NZ . LYS A 1 463 ? -28.305 -10.815 -32.829 1.00 59.06 ? 463 LYS A NZ 1 ATOM 3129 N N . THR A 1 464 ? -30.045 -17.109 -30.098 1.00 58.04 ? 464 THR A N 1 ATOM 3130 C CA . THR A 1 464 ? -31.458 -17.460 -30.173 1.00 59.19 ? 464 THR A CA 1 ATOM 3131 C C . THR A 1 464 ? -31.832 -18.501 -29.116 1.00 62.31 ? 464 THR A C 1 ATOM 3132 O O . THR A 1 464 ? -33.009 -18.691 -28.813 1.00 64.66 ? 464 THR A O 1 ATOM 3133 C CB . THR A 1 464 ? -31.846 -17.976 -31.576 1.00 55.19 ? 464 THR A CB 1 ATOM 3134 O OG1 . THR A 1 464 ? -30.980 -19.056 -31.947 1.00 59.19 ? 464 THR A OG1 1 ATOM 3135 C CG2 . THR A 1 464 ? -31.723 -16.863 -32.607 1.00 51.65 ? 464 THR A CG2 1 ATOM 3136 N N . ALA A 1 465 ? -30.829 -19.178 -28.565 1.00 58.90 ? 465 ALA A N 1 ATOM 3137 C CA . ALA A 1 465 ? -31.057 -20.099 -27.456 1.00 59.10 ? 465 ALA A CA 1 ATOM 3138 C C . ALA A 1 465 ? -31.187 -19.316 -26.158 1.00 59.57 ? 465 ALA A C 1 ATOM 3139 O O . ALA A 1 465 ? -31.970 -19.674 -25.277 1.00 55.70 ? 465 ALA A O 1 ATOM 3140 C CB . ALA A 1 465 ? -29.932 -21.115 -27.355 1.00 57.56 ? 465 ALA A CB 1 ATOM 3141 N N . TYR A 1 466 ? -30.406 -18.245 -26.050 1.00 63.30 ? 466 TYR A N 1 ATOM 3142 C CA . TYR A 1 466 ? -30.422 -17.388 -24.871 1.00 65.63 ? 466 TYR A CA 1 ATOM 3143 C C . TYR A 1 466 ? -31.628 -16.452 -24.879 1.00 61.07 ? 466 TYR A C 1 ATOM 3144 O O . TYR A 1 466 ? -32.268 -16.248 -23.845 1.00 58.88 ? 466 TYR A O 1 ATOM 3145 C CB . TYR A 1 466 ? -29.115 -16.589 -24.768 1.00 59.73 ? 466 TYR A CB 1 ATOM 3146 C CG . TYR A 1 466 ? -29.103 -15.546 -23.673 1.00 51.55 ? 466 TYR A CG 1 ATOM 3147 C CD1 . TYR A 1 466 ? -29.455 -15.872 -22.372 1.00 58.66 ? 466 TYR A CD1 1 ATOM 3148 C CD2 . TYR A 1 466 ? -28.725 -14.238 -23.940 1.00 46.24 ? 466 TYR A CD2 1 ATOM 3149 C CE1 . TYR A 1 466 ? -29.446 -14.921 -21.369 1.00 62.48 ? 466 TYR A CE1 1 ATOM 3150 C CE2 . TYR A 1 466 ? -28.711 -13.281 -22.945 1.00 49.97 ? 466 TYR A CE2 1 ATOM 3151 C CZ . TYR A 1 466 ? -29.073 -13.627 -21.661 1.00 57.70 ? 466 TYR A CZ 1 ATOM 3152 O OH . TYR A 1 466 ? -29.060 -12.677 -20.665 1.00 51.37 ? 466 TYR A OH 1 ATOM 3153 N N . ALA A 1 467 ? -31.936 -15.895 -26.048 1.00 53.73 ? 467 ALA A N 1 ATOM 3154 C CA . ALA A 1 467 ? -33.061 -14.977 -26.196 1.00 49.75 ? 467 ALA A CA 1 ATOM 3155 C C . ALA A 1 467 ? -34.375 -15.620 -25.768 1.00 60.66 ? 467 ALA A C 1 ATOM 3156 O O . ALA A 1 467 ? -35.188 -14.994 -25.086 1.00 59.19 ? 467 ALA A O 1 ATOM 3157 C CB . ALA A 1 467 ? -33.155 -14.483 -27.628 1.00 49.17 ? 467 ALA A CB 1 ATOM 3158 N N . LEU A 1 468 ? -34.584 -16.871 -26.171 1.00 67.21 ? 468 LEU A N 1 ATOM 3159 C CA . LEU A 1 468 ? -35.768 -17.598 -25.736 1.00 70.54 ? 468 LEU A CA 1 ATOM 3160 C C . LEU A 1 468 ? -35.386 -18.665 -24.714 1.00 72.59 ? 468 LEU A C 1 ATOM 3161 O O . LEU A 1 468 ? -34.845 -19.711 -25.069 1.00 78.07 ? 468 LEU A O 1 ATOM 3162 C CB . LEU A 1 468 ? -36.457 -18.270 -26.932 1.00 65.92 ? 468 LEU A CB 1 ATOM 3163 C CG . LEU A 1 468 ? -36.924 -17.439 -28.135 1.00 58.28 ? 468 LEU A CG 1 ATOM 3164 C CD1 . LEU A 1 468 ? -37.530 -16.112 -27.699 1.00 61.60 ? 468 LEU A CD1 1 ATOM 3165 C CD2 . LEU A 1 468 ? -35.808 -17.222 -29.147 1.00 45.57 ? 468 LEU A CD2 1 ATOM 3166 N N . SER A 1 469 ? -35.677 -18.399 -23.444 1.00 70.94 ? 469 SER A N 1 ATOM 3167 C CA . SER A 1 469 ? -35.535 -19.406 -22.399 1.00 74.12 ? 469 SER A CA 1 ATOM 3168 C C . SER A 1 469 ? -36.474 -19.133 -21.230 1.00 73.70 ? 469 SER A C 1 ATOM 3169 O O . SER A 1 469 ? -36.680 -17.982 -20.845 1.00 66.91 ? 469 SER A O 1 ATOM 3170 C CB . SER A 1 469 ? -34.081 -19.498 -21.918 1.00 75.49 ? 469 SER A CB 1 ATOM 3171 O OG . SER A 1 469 ? -33.524 -18.214 -21.699 1.00 69.84 ? 469 SER A OG 1 ATOM 3172 N N . ARG A 1 470 ? -37.042 -20.196 -20.674 1.00 78.68 ? 470 ARG A N 1 ATOM 3173 C CA . ARG A 1 470 ? -37.791 -20.107 -19.429 1.00 83.94 ? 470 ARG A CA 1 ATOM 3174 C C . ARG A 1 470 ? -36.857 -20.527 -18.303 1.00 87.84 ? 470 ARG A C 1 ATOM 3175 O O . ARG A 1 470 ? -37.255 -20.634 -17.143 1.00 92.64 ? 470 ARG A O 1 ATOM 3176 C CB . ARG A 1 470 ? -39.037 -20.995 -19.476 1.00 92.12 ? 470 ARG A CB 1 ATOM 3177 C CG . ARG A 1 470 ? -40.121 -20.609 -18.473 1.00 102.50 ? 470 ARG A CG 1 ATOM 3178 C CD . ARG A 1 470 ? -40.357 -19.099 -18.462 1.00 103.65 ? 470 ARG A CD 1 ATOM 3179 N NE . ARG A 1 470 ? -41.481 -18.715 -17.610 1.00 105.70 ? 470 ARG A NE 1 ATOM 3180 C CZ . ARG A 1 470 ? -41.799 -17.459 -17.308 1.00 100.47 ? 470 ARG A CZ 1 ATOM 3181 N NH1 . ARG A 1 470 ? -41.074 -16.453 -17.781 1.00 89.70 ? 470 ARG A NH1 1 ATOM 3182 N NH2 . ARG A 1 470 ? -42.841 -17.207 -16.527 1.00 96.82 ? 470 ARG A NH2 1 ATOM 3183 N N . GLY A 1 471 ? -35.603 -20.767 -18.671 1.00 89.04 ? 471 GLY A N 1 ATOM 3184 C CA . GLY A 1 471 ? -34.621 -21.338 -17.771 1.00 91.88 ? 471 GLY A CA 1 ATOM 3185 C C . GLY A 1 471 ? -34.366 -22.766 -18.202 1.00 94.72 ? 471 GLY A C 1 ATOM 3186 O O . GLY A 1 471 ? -33.384 -23.392 -17.801 1.00 95.76 ? 471 GLY A O 1 ATOM 3187 N N . GLN A 1 472 ? -35.266 -23.272 -19.039 1.00 91.41 ? 472 GLN A N 1 ATOM 3188 C CA . GLN A 1 472 ? -35.113 -24.587 -19.642 1.00 90.81 ? 472 GLN A CA 1 ATOM 3189 C C . GLN A 1 472 ? -34.300 -24.455 -20.923 1.00 90.87 ? 472 GLN A C 1 ATOM 3190 O O . GLN A 1 472 ? -34.722 -23.798 -21.875 1.00 85.79 ? 472 GLN A O 1 ATOM 3191 C CB . GLN A 1 472 ? -36.489 -25.183 -19.950 1.00 89.03 ? 472 GLN A CB 1 ATOM 3192 C CG . GLN A 1 472 ? -36.463 -26.429 -20.823 1.00 95.75 ? 472 GLN A CG 1 ATOM 3193 C CD . GLN A 1 472 ? -37.845 -26.826 -21.317 1.00 98.32 ? 472 GLN A CD 1 ATOM 3194 O OE1 . GLN A 1 472 ? -38.850 -26.222 -20.940 1.00 96.02 ? 472 GLN A OE1 1 ATOM 3195 N NE2 . GLN A 1 472 ? -37.899 -27.843 -22.170 1.00 97.05 ? 472 GLN A NE2 1 ATOM 3196 N N . ASP A 1 473 ? -33.132 -25.085 -20.945 1.00 91.15 ? 473 ASP A N 1 ATOM 3197 C CA . ASP A 1 473 ? -32.265 -25.037 -22.112 1.00 86.18 ? 473 ASP A CA 1 ATOM 3198 C C . ASP A 1 473 ? -31.994 -26.454 -22.594 1.00 87.24 ? 473 ASP A C 1 ATOM 3199 O O . ASP A 1 473 ? -31.789 -27.359 -21.785 1.00 86.99 ? 473 ASP A O 1 ATOM 3200 C CB . ASP A 1 473 ? -30.952 -24.330 -21.774 1.00 90.34 ? 473 ASP A CB 1 ATOM 3201 C CG . ASP A 1 473 ? -31.162 -22.902 -21.308 1.00 100.45 ? 473 ASP A CG 1 ATOM 3202 O OD1 . ASP A 1 473 ? -32.196 -22.301 -21.670 1.00 97.67 ? 473 ASP A OD1 1 ATOM 3203 O OD2 . ASP A 1 473 ? -30.289 -22.378 -20.583 1.00 99.49 ? 473 ASP A OD2 1 ATOM 3204 N N . HIS A 1 474 ? -32.001 -26.647 -23.909 1.00 94.36 ? 474 HIS A N 1 ATOM 3205 C CA . HIS A 1 474 ? -31.772 -27.970 -24.482 1.00 94.87 ? 474 HIS A CA 1 ATOM 3206 C C . HIS A 1 474 ? -30.357 -28.450 -24.169 1.00 86.71 ? 474 HIS A C 1 ATOM 3207 O O . HIS A 1 474 ? -29.421 -27.652 -24.109 1.00 72.81 ? 474 HIS A O 1 ATOM 3208 C CB . HIS A 1 474 ? -32.018 -27.960 -25.995 1.00 88.31 ? 474 HIS A CB 1 ATOM 3209 C CG . HIS A 1 474 ? -32.529 -29.260 -26.534 1.00 84.46 ? 474 HIS A CG 1 ATOM 3210 N ND1 . HIS A 1 474 ? -31.711 -30.192 -27.136 1.00 82.86 ? 474 HIS A ND1 1 ATOM 3211 C CD2 . HIS A 1 474 ? -33.778 -29.782 -26.563 1.00 86.60 ? 474 HIS A CD2 1 ATOM 3212 C CE1 . HIS A 1 474 ? -32.434 -31.231 -27.513 1.00 91.03 ? 474 HIS A CE1 1 ATOM 3213 N NE2 . HIS A 1 474 ? -33.692 -31.008 -27.176 1.00 92.60 ? 474 HIS A NE2 1 ATOM 3214 N N . VAL A 1 475 ? -30.215 -29.755 -23.959 1.00 88.63 ? 475 VAL A N 1 ATOM 3215 C CA . VAL A 1 475 ? -28.935 -30.352 -23.592 1.00 79.46 ? 475 VAL A CA 1 ATOM 3216 C C . VAL A 1 475 ? -27.871 -30.100 -24.659 1.00 75.98 ? 475 VAL A C 1 ATOM 3217 O O . VAL A 1 475 ? -26.702 -29.878 -24.343 1.00 83.89 ? 475 VAL A O 1 ATOM 3218 C CB . VAL A 1 475 ? -29.082 -31.868 -23.337 1.00 80.84 ? 475 VAL A CB 1 ATOM 3219 C CG1 . VAL A 1 475 ? -27.763 -32.470 -22.875 1.00 84.53 ? 475 VAL A CG1 1 ATOM 3220 C CG2 . VAL A 1 475 ? -30.177 -32.126 -22.310 1.00 76.78 ? 475 VAL A CG2 1 ATOM 3221 N N . ASN A 1 476 ? -28.288 -30.118 -25.922 1.00 73.44 ? 476 ASN A N 1 ATOM 3222 C CA . ASN A 1 476 ? -27.378 -29.865 -27.035 1.00 75.81 ? 476 ASN A CA 1 ATOM 3223 C C . ASN A 1 476 ? -26.995 -28.390 -27.174 1.00 74.04 ? 476 ASN A C 1 ATOM 3224 O O . ASN A 1 476 ? -26.036 -28.053 -27.868 1.00 69.97 ? 476 ASN A O 1 ATOM 3225 C CB . ASN A 1 476 ? -27.969 -30.392 -28.347 1.00 83.98 ? 476 ASN A CB 1 ATOM 3226 C CG . ASN A 1 476 ? -28.075 -31.907 -28.374 1.00 85.11 ? 476 ASN A CG 1 ATOM 3227 O OD1 . ASN A 1 476 ? -27.318 -32.606 -27.701 1.00 85.48 ? 476 ASN A OD1 1 ATOM 3228 N ND2 . ASN A 1 476 ? -29.015 -32.421 -29.159 1.00 86.80 ? 476 ASN A ND2 1 ATOM 3229 N N . ALA A 1 477 ? -27.751 -27.516 -26.513 1.00 70.65 ? 477 ALA A N 1 ATOM 3230 C CA . ALA A 1 477 ? -27.436 -26.090 -26.500 1.00 73.14 ? 477 ALA A CA 1 ATOM 3231 C C . ALA A 1 477 ? -26.260 -25.800 -25.568 1.00 79.80 ? 477 ALA A C 1 ATOM 3232 O O . ALA A 1 477 ? -25.333 -25.073 -25.933 1.00 77.97 ? 477 ALA A O 1 ATOM 3233 C CB . ALA A 1 477 ? -28.654 -25.278 -26.087 1.00 71.44 ? 477 ALA A CB 1 ATOM 3234 N N . LEU A 1 478 ? -26.309 -26.369 -24.367 1.00 79.85 ? 478 LEU A N 1 ATOM 3235 C CA . LEU A 1 478 ? -25.224 -26.242 -23.401 1.00 64.06 ? 478 LEU A CA 1 ATOM 3236 C C . LEU A 1 478 ? -23.982 -26.951 -23.921 1.00 61.83 ? 478 LEU A C 1 ATOM 3237 O O . LEU A 1 478 ? -22.885 -26.397 -23.900 1.00 66.65 ? 478 LEU A O 1 ATOM 3238 C CB . LEU A 1 478 ? -25.630 -26.837 -22.051 1.00 59.70 ? 478 LEU A CB 1 ATOM 3239 C CG . LEU A 1 478 ? -26.871 -26.277 -21.356 1.00 62.92 ? 478 LEU A CG 1 ATOM 3240 C CD1 . LEU A 1 478 ? -27.100 -26.974 -20.023 1.00 66.92 ? 478 LEU A CD1 1 ATOM 3241 C CD2 . LEU A 1 478 ? -26.748 -24.781 -21.157 1.00 62.28 ? 478 LEU A CD2 1 ATOM 3242 N N . SER A 1 479 ? -24.171 -28.180 -24.394 1.00 61.16 ? 479 SER A N 1 ATOM 3243 C CA . SER A 1 479 ? -23.082 -28.978 -24.948 1.00 65.56 ? 479 SER A CA 1 ATOM 3244 C C . SER A 1 479 ? -22.407 -28.279 -26.127 1.00 75.32 ? 479 SER A C 1 ATOM 3245 O O . SER A 1 479 ? -21.253 -28.565 -26.448 1.00 81.64 ? 479 SER A O 1 ATOM 3246 C CB . SER A 1 479 ? -23.591 -30.359 -25.369 1.00 71.30 ? 479 SER A CB 1 ATOM 3247 O OG . SER A 1 479 ? -24.122 -31.064 -24.258 1.00 72.85 ? 479 SER A OG 1 ATOM 3248 N N . LEU A 1 480 ? -23.132 -27.370 -26.774 1.00 76.19 ? 480 LEU A N 1 ATOM 3249 C CA . LEU A 1 480 ? -22.537 -26.502 -27.783 1.00 79.88 ? 480 LEU A CA 1 ATOM 3250 C C . LEU A 1 480 ? -21.664 -25.449 -27.108 1.00 78.88 ? 480 LEU A C 1 ATOM 3251 O O . LEU A 1 480 ? -20.506 -25.264 -27.480 1.00 74.77 ? 480 LEU A O 1 ATOM 3252 C CB . LEU A 1 480 ? -23.615 -25.824 -28.634 1.00 76.12 ? 480 LEU A CB 1 ATOM 3253 C CG . LEU A 1 480 ? -23.088 -24.758 -29.600 1.00 76.55 ? 480 LEU A CG 1 ATOM 3254 C CD1 . LEU A 1 480 ? -22.111 -25.369 -30.593 1.00 81.90 ? 480 LEU A CD1 1 ATOM 3255 C CD2 . LEU A 1 480 ? -24.221 -24.050 -30.328 1.00 77.30 ? 480 LEU A CD2 1 ATOM 3256 N N . ALA A 1 481 ? -22.227 -24.779 -26.104 1.00 81.48 ? 481 ALA A N 1 ATOM 3257 C CA . ALA A 1 481 ? -21.548 -23.696 -25.392 1.00 78.82 ? 481 ALA A CA 1 ATOM 3258 C C . ALA A 1 481 ? -20.217 -24.124 -24.775 1.00 74.62 ? 481 ALA A C 1 ATOM 3259 O O . ALA A 1 481 ? -19.233 -23.384 -24.839 1.00 69.87 ? 481 ALA A O 1 ATOM 3260 C CB . ALA A 1 481 ? -22.464 -23.104 -24.326 1.00 70.14 ? 481 ALA A CB 1 ATOM 3261 N N . ARG A 1 482 ? -20.198 -25.311 -24.172 1.00 72.45 ? 482 ARG A N 1 ATOM 3262 C CA . ARG A 1 482 ? -18.975 -25.877 -23.615 1.00 66.79 ? 482 ARG A CA 1 ATOM 3263 C C . ARG A 1 482 ? -17.919 -25.973 -24.703 1.00 68.25 ? 482 ARG A C 1 ATOM 3264 O O . ARG A 1 482 ? -16.763 -25.603 -24.502 1.00 81.21 ? 482 ARG A O 1 ATOM 3265 C CB . ARG A 1 482 ? -19.228 -27.277 -23.053 1.00 62.20 ? 482 ARG A CB 1 ATOM 3266 C CG . ARG A 1 482 ? -20.426 -27.400 -22.131 1.00 63.62 ? 482 ARG A CG 1 ATOM 3267 C CD . ARG A 1 482 ? -20.472 -28.787 -21.505 1.00 63.37 ? 482 ARG A CD 1 ATOM 3268 N NE . ARG A 1 482 ? -21.836 -29.246 -21.267 1.00 62.76 ? 482 ARG A NE 1 ATOM 3269 C CZ . ARG A 1 482 ? -22.562 -28.910 -20.208 1.00 63.07 ? 482 ARG A CZ 1 ATOM 3270 N NH1 . ARG A 1 482 ? -22.057 -28.103 -19.286 1.00 58.48 ? 482 ARG A NH1 1 ATOM 3271 N NH2 . ARG A 1 482 ? -23.796 -29.377 -20.072 1.00 67.63 ? 482 ARG A NH2 1 ATOM 3272 N N . ARG A 1 483 ? -18.333 -26.476 -25.859 1.00 62.85 ? 483 ARG A N 1 ATOM 3273 C CA . ARG A 1 483 ? -17.436 -26.648 -26.991 1.00 75.04 ? 483 ARG A CA 1 ATOM 3274 C C . ARG A 1 483 ? -16.923 -25.302 -27.508 1.00 75.47 ? 483 ARG A C 1 ATOM 3275 O O . ARG A 1 483 ? -15.788 -25.204 -27.977 1.00 74.03 ? 483 ARG A O 1 ATOM 3276 C CB . ARG A 1 483 ? -18.138 -27.444 -28.098 1.00 90.64 ? 483 ARG A CB 1 ATOM 3277 C CG . ARG A 1 483 ? -17.290 -27.738 -29.328 1.00 103.17 ? 483 ARG A CG 1 ATOM 3278 C CD . ARG A 1 483 ? -17.782 -28.980 -30.076 1.00 99.38 ? 483 ARG A CD 1 ATOM 3279 N NE . ARG A 1 483 ? -19.204 -28.922 -30.413 1.00 98.59 ? 483 ARG A NE 1 ATOM 3280 C CZ . ARG A 1 483 ? -20.161 -29.557 -29.740 1.00 95.21 ? 483 ARG A CZ 1 ATOM 3281 N NH1 . ARG A 1 483 ? -19.852 -30.301 -28.687 1.00 91.00 ? 483 ARG A NH1 1 ATOM 3282 N NH2 . ARG A 1 483 ? -21.427 -29.447 -30.119 1.00 92.38 ? 483 ARG A NH2 1 ATOM 3283 N N . VAL A 1 484 ? -17.753 -24.265 -27.402 1.00 71.41 ? 484 VAL A N 1 ATOM 3284 C CA . VAL A 1 484 ? -17.376 -22.929 -27.866 1.00 71.10 ? 484 VAL A CA 1 ATOM 3285 C C . VAL A 1 484 ? -16.229 -22.336 -27.048 1.00 73.19 ? 484 VAL A C 1 ATOM 3286 O O . VAL A 1 484 ? -15.193 -21.964 -27.601 1.00 74.15 ? 484 VAL A O 1 ATOM 3287 C CB . VAL A 1 484 ? -18.568 -21.946 -27.827 1.00 67.85 ? 484 VAL A CB 1 ATOM 3288 C CG1 . VAL A 1 484 ? -18.136 -20.573 -28.322 1.00 62.79 ? 484 VAL A CG1 1 ATOM 3289 C CG2 . VAL A 1 484 ? -19.726 -22.469 -28.658 1.00 73.72 ? 484 VAL A CG2 1 ATOM 3290 N N . ILE A 1 485 ? -16.424 -22.259 -25.733 1.00 72.59 ? 485 ILE A N 1 ATOM 3291 C CA . ILE A 1 485 ? -15.442 -21.677 -24.816 1.00 66.65 ? 485 ILE A CA 1 ATOM 3292 C C . ILE A 1 485 ? -14.073 -22.342 -24.934 1.00 65.45 ? 485 ILE A C 1 ATOM 3293 O O . ILE A 1 485 ? -13.061 -21.669 -25.135 1.00 63.00 ? 485 ILE A O 1 ATOM 3294 C CB . ILE A 1 485 ? -15.923 -21.769 -23.348 1.00 56.37 ? 485 ILE A CB 1 ATOM 3295 C CG1 . ILE A 1 485 ? -17.119 -20.846 -23.113 1.00 56.52 ? 485 ILE A CG1 1 ATOM 3296 C CG2 . ILE A 1 485 ? -14.805 -21.413 -22.389 1.00 53.44 ? 485 ILE A CG2 1 ATOM 3297 C CD1 . ILE A 1 485 ? -17.586 -20.813 -21.670 1.00 62.64 ? 485 ILE A CD1 1 ATOM 3298 N N . MET A 1 486 ? -14.061 -23.667 -24.812 1.00 65.08 ? 486 MET A N 1 ATOM 3299 C CA . MET A 1 486 ? -12.841 -24.460 -24.925 1.00 64.46 ? 486 MET A CA 1 ATOM 3300 C C . MET A 1 486 ? -12.096 -24.199 -26.232 1.00 65.75 ? 486 MET A C 1 ATOM 3301 O O . MET A 1 486 ? -10.866 -24.197 -26.263 1.00 70.53 ? 486 MET A O 1 ATOM 3302 C CB . MET A 1 486 ? -13.167 -25.950 -24.802 1.00 61.50 ? 486 MET A CB 1 ATOM 3303 C CG . MET A 1 486 ? -13.440 -26.420 -23.383 1.00 58.00 ? 486 MET A CG 1 ATOM 3304 S SD . MET A 1 486 ? -11.966 -26.345 -22.348 1.00 80.28 ? 486 MET A SD 1 ATOM 3305 C CE . MET A 1 486 ? -10.837 -27.362 -23.299 1.00 79.64 ? 486 MET A CE 1 ATOM 3306 N N . SER A 1 487 ? -12.845 -23.976 -27.306 1.00 61.75 ? 487 SER A N 1 ATOM 3307 C CA . SER A 1 487 ? -12.249 -23.712 -28.613 1.00 65.95 ? 487 SER A CA 1 ATOM 3308 C C . SER A 1 487 ? -11.741 -22.275 -28.749 1.00 66.29 ? 487 SER A C 1 ATOM 3309 O O . SER A 1 487 ? -10.897 -21.988 -29.599 1.00 64.41 ? 487 SER A O 1 ATOM 3310 C CB . SER A 1 487 ? -13.236 -24.050 -29.733 1.00 69.28 ? 487 SER A CB 1 ATOM 3311 O OG . SER A 1 487 ? -14.536 -23.579 -29.426 1.00 76.77 ? 487 SER A OG 1 ATOM 3312 N N . ILE A 1 488 ? -12.266 -21.376 -27.921 1.00 63.78 ? 488 ILE A N 1 ATOM 3313 C CA . ILE A 1 488 ? -11.744 -20.014 -27.836 1.00 66.00 ? 488 ILE A CA 1 ATOM 3314 C C . ILE A 1 488 ? -10.495 -19.998 -26.959 1.00 68.68 ? 488 ILE A C 1 ATOM 3315 O O . ILE A 1 488 ? -9.509 -19.329 -27.269 1.00 69.28 ? 488 ILE A O 1 ATOM 3316 C CB . ILE A 1 488 ? -12.790 -19.034 -27.269 1.00 59.75 ? 488 ILE A CB 1 ATOM 3317 C CG1 . ILE A 1 488 ? -14.055 -19.058 -28.126 1.00 68.75 ? 488 ILE A CG1 1 ATOM 3318 C CG2 . ILE A 1 488 ? -12.227 -17.621 -27.203 1.00 52.00 ? 488 ILE A CG2 1 ATOM 3319 C CD1 . ILE A 1 488 ? -15.131 -18.123 -27.648 1.00 63.24 ? 488 ILE A CD1 1 ATOM 3320 N N . TYR A 1 489 ? -10.558 -20.744 -25.860 1.00 69.64 ? 489 TYR A N 1 ATOM 3321 C CA . TYR A 1 489 ? -9.434 -20.908 -24.941 1.00 65.56 ? 489 TYR A CA 1 ATOM 3322 C C . TYR A 1 489 ? -8.194 -21.437 -25.653 1.00 64.34 ? 489 TYR A C 1 ATOM 3323 O O . TYR A 1 489 ? -7.160 -20.769 -25.692 1.00 68.70 ? 489 TYR A O 1 ATOM 3324 C CB . TYR A 1 489 ? -9.816 -21.843 -23.789 1.00 66.18 ? 489 TYR A CB 1 ATOM 3325 C CG . TYR A 1 489 ? -8.760 -21.973 -22.715 1.00 64.89 ? 489 TYR A CG 1 ATOM 3326 C CD1 . TYR A 1 489 ? -8.558 -20.962 -21.787 1.00 66.30 ? 489 TYR A CD1 1 ATOM 3327 C CD2 . TYR A 1 489 ? -7.973 -23.112 -22.621 1.00 71.20 ? 489 TYR A CD2 1 ATOM 3328 C CE1 . TYR A 1 489 ? -7.596 -21.075 -20.802 1.00 67.85 ? 489 TYR A CE1 1 ATOM 3329 C CE2 . TYR A 1 489 ? -7.009 -23.235 -21.638 1.00 72.60 ? 489 TYR A CE2 1 ATOM 3330 C CZ . TYR A 1 489 ? -6.825 -22.214 -20.731 1.00 68.45 ? 489 TYR A CZ 1 ATOM 3331 O OH . TYR A 1 489 ? -5.868 -22.334 -19.752 1.00 68.11 ? 489 TYR A OH 1 ATOM 3332 N N . LYS A 1 490 ? -8.310 -22.643 -26.206 1.00 60.13 ? 490 LYS A N 1 ATOM 3333 C CA . LYS A 1 490 ? -7.195 -23.320 -26.868 1.00 63.17 ? 490 LYS A CA 1 ATOM 3334 C C . LYS A 1 490 ? -6.512 -22.469 -27.936 1.00 62.65 ? 490 LYS A C 1 ATOM 3335 O O . LYS A 1 490 ? -5.329 -22.650 -28.218 1.00 72.82 ? 490 LYS A O 1 ATOM 3336 C CB . LYS A 1 490 ? -7.658 -24.648 -27.477 1.00 69.74 ? 490 LYS A CB 1 ATOM 3337 C CG . LYS A 1 490 ? -8.051 -25.704 -26.456 1.00 77.35 ? 490 LYS A CG 1 ATOM 3338 C CD . LYS A 1 490 ? -8.300 -27.051 -27.120 1.00 82.19 ? 490 LYS A CD 1 ATOM 3339 C CE . LYS A 1 490 ? -7.050 -27.564 -27.822 1.00 97.84 ? 490 LYS A CE 1 ATOM 3340 N NZ . LYS A 1 490 ? -5.918 -27.788 -26.876 1.00 93.63 ? 490 LYS A NZ 1 ATOM 3341 N N . GLY A 1 491 ? -7.260 -21.550 -28.534 1.00 62.88 ? 491 GLY A N 1 ATOM 3342 C CA . GLY A 1 491 ? -6.694 -20.645 -29.515 1.00 76.17 ? 491 GLY A CA 1 ATOM 3343 C C . GLY A 1 491 ? -6.113 -19.394 -28.885 1.00 75.52 ? 491 GLY A C 1 ATOM 3344 O O . GLY A 1 491 ? -5.210 -18.772 -29.445 1.00 78.23 ? 491 GLY A O 1 ATOM 3345 N N . LEU A 1 492 ? -6.628 -19.027 -27.715 1.00 69.19 ? 492 LEU A N 1 ATOM 3346 C CA . LEU A 1 492 ? -6.200 -17.801 -27.042 1.00 71.63 ? 492 LEU A CA 1 ATOM 3347 C C . LEU A 1 492 ? -4.873 -17.937 -26.296 1.00 76.93 ? 492 LEU A C 1 ATOM 3348 O O . LEU A 1 492 ? -4.222 -16.936 -25.994 1.00 82.41 ? 492 LEU A O 1 ATOM 3349 C CB . LEU A 1 492 ? -7.292 -17.279 -26.101 1.00 64.14 ? 492 LEU A CB 1 ATOM 3350 C CG . LEU A 1 492 ? -8.235 -16.236 -26.704 1.00 59.79 ? 492 LEU A CG 1 ATOM 3351 C CD1 . LEU A 1 492 ? -9.177 -15.680 -25.650 1.00 63.52 ? 492 LEU A CD1 1 ATOM 3352 C CD2 . LEU A 1 492 ? -7.438 -15.117 -27.352 1.00 58.46 ? 492 LEU A CD2 1 ATOM 3353 N N . LEU A 1 493 ? -4.471 -19.170 -26.002 1.00 73.16 ? 493 LEU A N 1 ATOM 3354 C CA . LEU A 1 493 ? -3.162 -19.409 -25.404 1.00 69.68 ? 493 LEU A CA 1 ATOM 3355 C C . LEU A 1 493 ? -2.094 -19.436 -26.497 1.00 77.07 ? 493 LEU A C 1 ATOM 3356 O O . LEU A 1 493 ? -0.910 -19.638 -26.229 1.00 84.04 ? 493 LEU A O 1 ATOM 3357 C CB . LEU A 1 493 ? -3.153 -20.683 -24.546 1.00 57.70 ? 493 LEU A CB 1 ATOM 3358 C CG . LEU A 1 493 ? -3.820 -21.963 -25.054 1.00 55.53 ? 493 LEU A CG 1 ATOM 3359 C CD1 . LEU A 1 493 ? -2.943 -22.680 -26.065 1.00 65.85 ? 493 LEU A CD1 1 ATOM 3360 C CD2 . LEU A 1 493 ? -4.159 -22.888 -23.891 1.00 48.47 ? 493 LEU A CD2 1 ATOM 3361 N N . VAL A 1 494 ? -2.540 -19.235 -27.734 1.00 75.85 ? 494 VAL A N 1 ATOM 3362 C CA . VAL A 1 494 ? -1.648 -19.069 -28.873 1.00 78.19 ? 494 VAL A CA 1 ATOM 3363 C C . VAL A 1 494 ? -1.582 -17.599 -29.291 1.00 80.90 ? 494 VAL A C 1 ATOM 3364 O O . VAL A 1 494 ? -0.525 -16.975 -29.199 1.00 87.46 ? 494 VAL A O 1 ATOM 3365 C CB . VAL A 1 494 ? -2.081 -19.933 -30.074 1.00 80.98 ? 494 VAL A CB 1 ATOM 3366 C CG1 . VAL A 1 494 ? -1.183 -19.660 -31.274 1.00 79.89 ? 494 VAL A CG1 1 ATOM 3367 C CG2 . VAL A 1 494 ? -2.056 -21.411 -29.704 1.00 74.55 ? 494 VAL A CG2 1 ATOM 3368 N N . LYS A 1 495 ? -2.706 -17.043 -29.743 1.00 78.00 ? 495 LYS A N 1 ATOM 3369 C CA . LYS A 1 495 ? -2.717 -15.656 -30.209 1.00 82.02 ? 495 LYS A CA 1 ATOM 3370 C C . LYS A 1 495 ? -3.102 -14.650 -29.121 1.00 79.66 ? 495 LYS A C 1 ATOM 3371 O O . LYS A 1 495 ? -3.490 -15.032 -28.016 1.00 73.46 ? 495 LYS A O 1 ATOM 3372 C CB . LYS A 1 495 ? -3.655 -15.504 -31.410 1.00 84.56 ? 495 LYS A CB 1 ATOM 3373 C CG . LYS A 1 495 ? -5.099 -15.902 -31.135 1.00 84.03 ? 495 LYS A CG 1 ATOM 3374 C CD . LYS A 1 495 ? -5.967 -15.716 -32.374 1.00 92.29 ? 495 LYS A CD 1 ATOM 3375 C CE . LYS A 1 495 ? -7.411 -16.124 -32.113 1.00 92.07 ? 495 LYS A CE 1 ATOM 3376 N NZ . LYS A 1 495 ? -8.272 -15.937 -33.316 1.00 85.06 ? 495 LYS A NZ 1 ATOM 3377 N N . GLN A 1 496 ? -2.996 -13.364 -29.449 1.00 83.51 ? 496 GLN A N 1 ATOM 3378 C CA . GLN A 1 496 ? -3.234 -12.293 -28.479 1.00 82.67 ? 496 GLN A CA 1 ATOM 3379 C C . GLN A 1 496 ? -4.592 -11.578 -28.546 1.00 82.94 ? 496 GLN A C 1 ATOM 3380 O O . GLN A 1 496 ? -4.869 -10.709 -27.716 1.00 75.95 ? 496 GLN A O 1 ATOM 3381 C CB . GLN A 1 496 ? -2.097 -11.266 -28.535 1.00 81.26 ? 496 GLN A CB 1 ATOM 3382 C CG . GLN A 1 496 ? -0.705 -11.881 -28.444 1.00 84.14 ? 496 GLN A CG 1 ATOM 3383 C CD . GLN A 1 496 ? -0.501 -12.690 -27.176 1.00 91.42 ? 496 GLN A CD 1 ATOM 3384 O OE1 . GLN A 1 496 ? -1.111 -12.413 -26.141 1.00 86.13 ? 496 GLN A OE1 1 ATOM 3385 N NE2 . GLN A 1 496 ? 0.361 -13.697 -27.251 1.00 97.99 ? 496 GLN A NE2 1 ATOM 3386 N N . ASN A 1 497 ? -5.436 -11.931 -29.513 1.00 83.67 ? 497 ASN A N 1 ATOM 3387 C CA . ASN A 1 497 ? -6.644 -11.141 -29.762 1.00 77.69 ? 497 ASN A CA 1 ATOM 3388 C C . ASN A 1 497 ? -7.823 -11.924 -30.348 1.00 80.84 ? 497 ASN A C 1 ATOM 3389 O O . ASN A 1 497 ? -7.655 -13.037 -30.847 1.00 83.70 ? 497 ASN A O 1 ATOM 3390 C CB . ASN A 1 497 ? -6.312 -9.954 -30.669 1.00 73.20 ? 497 ASN A CB 1 ATOM 3391 C CG . ASN A 1 497 ? -7.165 -8.738 -30.372 1.00 73.15 ? 497 ASN A CG 1 ATOM 3392 O OD1 . ASN A 1 497 ? -8.170 -8.827 -29.668 1.00 77.00 ? 497 ASN A OD1 1 ATOM 3393 N ND2 . ASN A 1 497 ? -6.768 -7.593 -30.911 1.00 72.29 ? 497 ASN A ND2 1 ATOM 3394 N N . LEU A 1 498 ? -9.013 -11.329 -30.282 1.00 78.47 ? 498 LEU A N 1 ATOM 3395 C CA . LEU A 1 498 ? -10.230 -11.949 -30.805 1.00 76.25 ? 498 LEU A CA 1 ATOM 3396 C C . LEU A 1 498 ? -10.947 -11.059 -31.824 1.00 80.25 ? 498 LEU A C 1 ATOM 3397 O O . LEU A 1 498 ? -11.147 -9.869 -31.582 1.00 78.32 ? 498 LEU A O 1 ATOM 3398 C CB . LEU A 1 498 ? -11.192 -12.293 -29.661 1.00 63.94 ? 498 LEU A CB 1 ATOM 3399 C CG . LEU A 1 498 ? -10.809 -13.458 -28.750 1.00 61.52 ? 498 LEU A CG 1 ATOM 3400 C CD1 . LEU A 1 498 ? -11.948 -13.811 -27.810 1.00 47.86 ? 498 LEU A CD1 1 ATOM 3401 C CD2 . LEU A 1 498 ? -10.420 -14.660 -29.584 1.00 78.06 ? 498 LEU A CD2 1 ATOM 3402 N N . ASN A 1 499 ? -11.328 -11.639 -32.962 1.00 86.26 ? 499 ASN A N 1 ATOM 3403 C CA . ASN A 1 499 ? -12.155 -10.932 -33.943 1.00 85.33 ? 499 ASN A CA 1 ATOM 3404 C C . ASN A 1 499 ? -13.631 -10.868 -33.536 1.00 79.57 ? 499 ASN A C 1 ATOM 3405 O O . ASN A 1 499 ? -14.084 -11.662 -32.710 1.00 75.38 ? 499 ASN A O 1 ATOM 3406 C CB . ASN A 1 499 ? -11.977 -11.497 -35.365 1.00 90.83 ? 499 ASN A CB 1 ATOM 3407 C CG . ASN A 1 499 ? -12.398 -12.957 -35.492 1.00 91.44 ? 499 ASN A CG 1 ATOM 3408 O OD1 . ASN A 1 499 ? -13.371 -13.398 -34.882 1.00 86.43 ? 499 ASN A OD1 1 ATOM 3409 N ND2 . ASN A 1 499 ? -11.658 -13.714 -36.303 1.00 96.95 ? 499 ASN A ND2 1 ATOM 3410 N N . ALA A 1 500 ? -14.366 -9.918 -34.110 1.00 77.78 ? 500 ALA A N 1 ATOM 3411 C CA . ALA A 1 500 ? -15.769 -9.688 -33.757 1.00 74.86 ? 500 ALA A CA 1 ATOM 3412 C C . ALA A 1 500 ? -16.639 -10.947 -33.824 1.00 74.10 ? 500 ALA A C 1 ATOM 3413 O O . ALA A 1 500 ? -17.582 -11.096 -33.047 1.00 70.29 ? 500 ALA A O 1 ATOM 3414 C CB . ALA A 1 500 ? -16.362 -8.581 -34.624 1.00 81.92 ? 500 ALA A CB 1 ATOM 3415 N N . THR A 1 501 ? -16.318 -11.843 -34.754 1.00 77.52 ? 501 THR A N 1 ATOM 3416 C CA . THR A 1 501 ? -17.010 -13.122 -34.865 1.00 75.46 ? 501 THR A CA 1 ATOM 3417 C C . THR A 1 501 ? -16.805 -13.943 -33.594 1.00 70.73 ? 501 THR A C 1 ATOM 3418 O O . THR A 1 501 ? -17.751 -14.507 -33.044 1.00 61.72 ? 501 THR A O 1 ATOM 3419 C CB . THR A 1 501 ? -16.491 -13.930 -36.069 1.00 83.10 ? 501 THR A CB 1 ATOM 3420 O OG1 . THR A 1 501 ? -16.413 -13.082 -37.222 1.00 86.00 ? 501 THR A OG1 1 ATOM 3421 C CG2 . THR A 1 501 ? -17.409 -15.107 -36.364 1.00 80.82 ? 501 THR A CG2 1 ATOM 3422 N N . GLU A 1 502 ? -15.556 -13.997 -33.139 1.00 77.15 ? 502 GLU A N 1 ATOM 3423 C CA . GLU A 1 502 ? -15.191 -14.708 -31.918 1.00 74.28 ? 502 GLU A CA 1 ATOM 3424 C C . GLU A 1 502 ? -15.740 -14.003 -30.680 1.00 70.17 ? 502 GLU A C 1 ATOM 3425 O O . GLU A 1 502 ? -16.265 -14.649 -29.772 1.00 68.22 ? 502 GLU A O 1 ATOM 3426 C CB . GLU A 1 502 ? -13.667 -14.829 -31.807 1.00 70.22 ? 502 GLU A CB 1 ATOM 3427 C CG . GLU A 1 502 ? -13.028 -15.771 -32.821 1.00 76.88 ? 502 GLU A CG 1 ATOM 3428 C CD . GLU A 1 502 ? -11.514 -15.645 -32.868 1.00 90.18 ? 502 GLU A CD 1 ATOM 3429 O OE1 . GLU A 1 502 ? -11.010 -14.502 -32.872 1.00 90.92 ? 502 GLU A OE1 1 ATOM 3430 O OE2 . GLU A 1 502 ? -10.827 -16.689 -32.901 1.00 98.18 ? 502 GLU A OE2 1 ATOM 3431 N N . ARG A 1 503 ? -15.609 -12.679 -30.651 1.00 66.07 ? 503 ARG A N 1 ATOM 3432 C CA . ARG A 1 503 ? -16.059 -11.878 -29.516 1.00 63.23 ? 503 ARG A CA 1 ATOM 3433 C C . ARG A 1 503 ? -17.535 -12.105 -29.196 1.00 62.22 ? 503 ARG A C 1 ATOM 3434 O O . ARG A 1 503 ? -17.905 -12.295 -28.038 1.00 55.85 ? 503 ARG A O 1 ATOM 3435 C CB . ARG A 1 503 ? -15.806 -10.390 -29.773 1.00 59.44 ? 503 ARG A CB 1 ATOM 3436 C CG . ARG A 1 503 ? -14.356 -10.024 -30.058 1.00 60.22 ? 503 ARG A CG 1 ATOM 3437 C CD . ARG A 1 503 ? -14.167 -8.519 -29.978 1.00 60.49 ? 503 ARG A CD 1 ATOM 3438 N NE . ARG A 1 503 ? -12.989 -8.038 -30.694 1.00 74.93 ? 503 ARG A NE 1 ATOM 3439 C CZ . ARG A 1 503 ? -12.725 -6.753 -30.913 1.00 75.80 ? 503 ARG A CZ 1 ATOM 3440 N NH1 . ARG A 1 503 ? -13.557 -5.816 -30.474 1.00 64.58 ? 503 ARG A NH1 1 ATOM 3441 N NH2 . ARG A 1 503 ? -11.631 -6.401 -31.574 1.00 80.35 ? 503 ARG A NH2 1 ATOM 3442 N N . GLN A 1 504 ? -18.371 -12.083 -30.231 1.00 66.15 ? 504 GLN A N 1 ATOM 3443 C CA . GLN A 1 504 ? -19.805 -12.310 -30.073 1.00 58.06 ? 504 GLN A CA 1 ATOM 3444 C C . GLN A 1 504 ? -20.098 -13.755 -29.684 1.00 56.79 ? 504 GLN A C 1 ATOM 3445 O O . GLN A 1 504 ? -20.977 -14.022 -28.867 1.00 55.15 ? 504 GLN A O 1 ATOM 3446 C CB . GLN A 1 504 ? -20.559 -11.958 -31.360 1.00 61.63 ? 504 GLN A CB 1 ATOM 3447 C CG . GLN A 1 504 ? -20.701 -10.466 -31.633 1.00 59.91 ? 504 GLN A CG 1 ATOM 3448 C CD . GLN A 1 504 ? -21.739 -10.166 -32.705 1.00 67.25 ? 504 GLN A CD 1 ATOM 3449 O OE1 . GLN A 1 504 ? -22.452 -11.058 -33.161 1.00 65.63 ? 504 GLN A OE1 1 ATOM 3450 N NE2 . GLN A 1 504 ? -21.828 -8.903 -33.108 1.00 67.85 ? 504 GLN A NE2 1 ATOM 3451 N N . ALA A 1 505 ? -19.358 -14.684 -30.281 1.00 56.32 ? 505 ALA A N 1 ATOM 3452 C CA . ALA A 1 505 ? -19.532 -16.106 -30.004 1.00 57.63 ? 505 ALA A CA 1 ATOM 3453 C C . ALA A 1 505 ? -19.300 -16.414 -28.528 1.00 60.34 ? 505 ALA A C 1 ATOM 3454 O O . ALA A 1 505 ? -20.024 -17.208 -27.926 1.00 54.22 ? 505 ALA A O 1 ATOM 3455 C CB . ALA A 1 505 ? -18.599 -16.925 -30.870 1.00 65.76 ? 505 ALA A CB 1 ATOM 3456 N N . LEU A 1 506 ? -18.283 -15.777 -27.954 1.00 62.70 ? 506 LEU A N 1 ATOM 3457 C CA . LEU A 1 506 ? -17.952 -15.952 -26.544 1.00 62.88 ? 506 LEU A CA 1 ATOM 3458 C C . LEU A 1 506 ? -19.042 -15.426 -25.610 1.00 62.63 ? 506 LEU A C 1 ATOM 3459 O O . LEU A 1 506 ? -19.386 -16.078 -24.623 1.00 59.81 ? 506 LEU A O 1 ATOM 3460 C CB . LEU A 1 506 ? -16.622 -15.267 -26.218 1.00 53.85 ? 506 LEU A CB 1 ATOM 3461 C CG . LEU A 1 506 ? -16.190 -15.348 -24.753 1.00 59.20 ? 506 LEU A CG 1 ATOM 3462 C CD1 . LEU A 1 506 ? -16.075 -16.795 -24.303 1.00 59.59 ? 506 LEU A CD1 1 ATOM 3463 C CD2 . LEU A 1 506 ? -14.882 -14.616 -24.536 1.00 55.96 ? 506 LEU A CD2 1 ATOM 3464 N N . PHE A 1 507 ? -19.570 -14.246 -25.928 1.00 61.18 ? 507 PHE A N 1 ATOM 3465 C CA . PHE A 1 507 ? -20.570 -13.571 -25.099 1.00 49.94 ? 507 PHE A CA 1 ATOM 3466 C C . PHE A 1 507 ? -21.729 -14.482 -24.717 1.00 53.19 ? 507 PHE A C 1 ATOM 3467 O O . PHE A 1 507 ? -21.923 -14.796 -23.543 1.00 54.61 ? 507 PHE A O 1 ATOM 3468 C CB . PHE A 1 507 ? -21.105 -12.327 -25.821 1.00 48.41 ? 507 PHE A CB 1 ATOM 3469 C CG . PHE A 1 507 ? -22.177 -11.591 -25.063 1.00 49.29 ? 507 PHE A CG 1 ATOM 3470 C CD1 . PHE A 1 507 ? -23.519 -11.877 -25.271 1.00 54.49 ? 507 PHE A CD1 1 ATOM 3471 C CD2 . PHE A 1 507 ? -21.845 -10.604 -24.150 1.00 50.02 ? 507 PHE A CD2 1 ATOM 3472 C CE1 . PHE A 1 507 ? -24.506 -11.200 -24.577 1.00 50.67 ? 507 PHE A CE1 1 ATOM 3473 C CE2 . PHE A 1 507 ? -22.829 -9.923 -23.454 1.00 50.60 ? 507 PHE A CE2 1 ATOM 3474 C CZ . PHE A 1 507 ? -24.160 -10.223 -23.668 1.00 46.76 ? 507 PHE A CZ 1 ATOM 3475 N N . PHE A 1 508 ? -22.494 -14.901 -25.719 1.00 56.52 ? 508 PHE A N 1 ATOM 3476 C CA . PHE A 1 508 ? -23.683 -15.710 -25.487 1.00 58.35 ? 508 PHE A CA 1 ATOM 3477 C C . PHE A 1 508 ? -23.336 -17.062 -24.866 1.00 60.23 ? 508 PHE A C 1 ATOM 3478 O O . PHE A 1 508 ? -24.119 -17.613 -24.095 1.00 59.90 ? 508 PHE A O 1 ATOM 3479 C CB . PHE A 1 508 ? -24.466 -15.894 -26.788 1.00 57.68 ? 508 PHE A CB 1 ATOM 3480 C CG . PHE A 1 508 ? -24.885 -14.600 -27.436 1.00 54.13 ? 508 PHE A CG 1 ATOM 3481 C CD1 . PHE A 1 508 ? -25.991 -13.902 -26.975 1.00 53.20 ? 508 PHE A CD1 1 ATOM 3482 C CD2 . PHE A 1 508 ? -24.181 -14.087 -28.515 1.00 54.37 ? 508 PHE A CD2 1 ATOM 3483 C CE1 . PHE A 1 508 ? -26.382 -12.715 -27.572 1.00 55.37 ? 508 PHE A CE1 1 ATOM 3484 C CE2 . PHE A 1 508 ? -24.567 -12.901 -29.117 1.00 54.35 ? 508 PHE A CE2 1 ATOM 3485 C CZ . PHE A 1 508 ? -25.668 -12.215 -28.645 1.00 55.77 ? 508 PHE A CZ 1 ATOM 3486 N N . ALA A 1 509 ? -22.159 -17.585 -25.197 1.00 60.48 ? 509 ALA A N 1 ATOM 3487 C CA . ALA A 1 509 ? -21.673 -18.823 -24.594 1.00 63.74 ? 509 ALA A CA 1 ATOM 3488 C C . ALA A 1 509 ? -21.584 -18.682 -23.076 1.00 65.83 ? 509 ALA A C 1 ATOM 3489 O O . ALA A 1 509 ? -21.923 -19.605 -22.334 1.00 62.52 ? 509 ALA A O 1 ATOM 3490 C CB . ALA A 1 509 ? -20.322 -19.202 -25.177 1.00 58.55 ? 509 ALA A CB 1 ATOM 3491 N N . SER A 1 510 ? -21.126 -17.518 -22.625 1.00 64.92 ? 510 SER A N 1 ATOM 3492 C CA . SER A 1 510 ? -21.058 -17.214 -21.200 1.00 61.49 ? 510 SER A CA 1 ATOM 3493 C C . SER A 1 510 ? -22.458 -17.033 -20.626 1.00 62.40 ? 510 SER A C 1 ATOM 3494 O O . SER A 1 510 ? -22.817 -17.665 -19.634 1.00 63.59 ? 510 SER A O 1 ATOM 3495 C CB . SER A 1 510 ? -20.239 -15.942 -20.959 1.00 56.55 ? 510 SER A CB 1 ATOM 3496 O OG . SER A 1 510 ? -18.939 -16.050 -21.511 1.00 59.18 ? 510 SER A OG 1 ATOM 3497 N N . MET A 1 511 ? -23.243 -16.169 -21.265 1.00 60.33 ? 511 MET A N 1 ATOM 3498 C CA . MET A 1 511 ? -24.588 -15.840 -20.798 1.00 58.77 ? 511 MET A CA 1 ATOM 3499 C C . MET A 1 511 ? -25.494 -17.068 -20.725 1.00 65.46 ? 511 MET A C 1 ATOM 3500 O O . MET A 1 511 ? -26.437 -17.106 -19.935 1.00 68.94 ? 511 MET A O 1 ATOM 3501 C CB . MET A 1 511 ? -25.226 -14.779 -21.700 1.00 54.67 ? 511 MET A CB 1 ATOM 3502 C CG . MET A 1 511 ? -24.438 -13.485 -21.821 1.00 44.00 ? 511 MET A CG 1 ATOM 3503 S SD . MET A 1 511 ? -24.114 -12.683 -20.240 1.00 58.65 ? 511 MET A SD 1 ATOM 3504 C CE . MET A 1 511 ? -25.775 -12.475 -19.601 1.00 63.73 ? 511 MET A CE 1 ATOM 3505 N N . ILE A 1 512 ? -25.204 -18.065 -21.556 1.00 65.67 ? 512 ILE A N 1 ATOM 3506 C CA . ILE A 1 512 ? -25.951 -19.319 -21.567 1.00 70.09 ? 512 ILE A CA 1 ATOM 3507 C C . ILE A 1 512 ? -25.659 -20.148 -20.313 1.00 71.84 ? 512 ILE A C 1 ATOM 3508 O O . ILE A 1 512 ? -26.576 -20.642 -19.654 1.00 75.20 ? 512 ILE A O 1 ATOM 3509 C CB . ILE A 1 512 ? -25.633 -20.144 -22.843 1.00 68.57 ? 512 ILE A CB 1 ATOM 3510 C CG1 . ILE A 1 512 ? -26.515 -19.693 -24.010 1.00 65.56 ? 512 ILE A CG1 1 ATOM 3511 C CG2 . ILE A 1 512 ? -25.818 -21.632 -22.600 1.00 70.60 ? 512 ILE A CG2 1 ATOM 3512 C CD1 . ILE A 1 512 ? -27.994 -19.925 -23.786 1.00 67.40 ? 512 ILE A CD1 1 ATOM 3513 N N . LEU A 1 513 ? -24.377 -20.279 -19.981 1.00 65.73 ? 513 LEU A N 1 ATOM 3514 C CA . LEU A 1 513 ? -23.945 -21.125 -18.872 1.00 62.53 ? 513 LEU A CA 1 ATOM 3515 C C . LEU A 1 513 ? -24.145 -20.476 -17.500 1.00 68.47 ? 513 LEU A C 1 ATOM 3516 O O . LEU A 1 513 ? -24.228 -21.170 -16.487 1.00 73.22 ? 513 LEU A O 1 ATOM 3517 C CB . LEU A 1 513 ? -22.485 -21.546 -19.067 1.00 58.93 ? 513 LEU A CB 1 ATOM 3518 C CG . LEU A 1 513 ? -22.253 -22.551 -20.199 1.00 59.20 ? 513 LEU A CG 1 ATOM 3519 C CD1 . LEU A 1 513 ? -20.873 -22.392 -20.817 1.00 57.88 ? 513 LEU A CD1 1 ATOM 3520 C CD2 . LEU A 1 513 ? -22.445 -23.969 -19.686 1.00 58.61 ? 513 LEU A CD2 1 ATOM 3521 N N . LEU A 1 514 ? -24.222 -19.149 -17.475 1.00 71.23 ? 514 LEU A N 1 ATOM 3522 C CA . LEU A 1 514 ? -24.449 -18.411 -16.234 1.00 70.86 ? 514 LEU A CA 1 ATOM 3523 C C . LEU A 1 514 ? -25.933 -18.097 -16.034 1.00 73.03 ? 514 LEU A C 1 ATOM 3524 O O . LEU A 1 514 ? -26.314 -17.458 -15.053 1.00 65.92 ? 514 LEU A O 1 ATOM 3525 C CB . LEU A 1 514 ? -23.640 -17.110 -16.228 1.00 59.67 ? 514 LEU A CB 1 ATOM 3526 C CG . LEU A 1 514 ? -22.153 -17.214 -16.570 1.00 44.30 ? 514 LEU A CG 1 ATOM 3527 C CD1 . LEU A 1 514 ? -21.476 -15.856 -16.464 1.00 37.63 ? 514 LEU A CD1 1 ATOM 3528 C CD2 . LEU A 1 514 ? -21.468 -18.230 -15.679 1.00 44.71 ? 514 LEU A CD2 1 ATOM 3529 N N . ASN A 1 515 ? -26.762 -18.554 -16.968 1.00 78.18 ? 515 ASN A N 1 ATOM 3530 C CA . ASN A 1 515 ? -28.181 -18.205 -16.993 1.00 81.98 ? 515 ASN A CA 1 ATOM 3531 C C . ASN A 1 515 ? -28.981 -18.772 -15.819 1.00 95.86 ? 515 ASN A C 1 ATOM 3532 O O . ASN A 1 515 ? -29.829 -18.086 -15.245 1.00 102.22 ? 515 ASN A O 1 ATOM 3533 C CB . ASN A 1 515 ? -28.808 -18.648 -18.320 1.00 79.16 ? 515 ASN A CB 1 ATOM 3534 C CG . ASN A 1 515 ? -30.040 -17.841 -18.683 1.00 78.81 ? 515 ASN A CG 1 ATOM 3535 O OD1 . ASN A 1 515 ? -30.175 -16.682 -18.289 1.00 74.87 ? 515 ASN A OD1 1 ATOM 3536 N ND2 . ASN A 1 515 ? -30.944 -18.449 -19.442 1.00 79.07 ? 515 ASN A ND2 1 ATOM 3537 N N . PHE A 1 516 ? -28.709 -20.023 -15.465 1.00 99.78 ? 516 PHE A N 1 ATOM 3538 C CA . PHE A 1 516 ? -29.423 -20.683 -14.377 1.00 109.26 ? 516 PHE A CA 1 ATOM 3539 C C . PHE A 1 516 ? -28.577 -20.765 -13.109 1.00 117.36 ? 516 PHE A C 1 ATOM 3540 O O . PHE A 1 516 ? -28.365 -21.848 -12.562 1.00 120.77 ? 516 PHE A O 1 ATOM 3541 C CB . PHE A 1 516 ? -29.868 -22.081 -14.808 1.00 111.09 ? 516 PHE A CB 1 ATOM 3542 C CG . PHE A 1 516 ? -28.954 -22.723 -15.814 1.00 110.24 ? 516 PHE A CG 1 ATOM 3543 C CD1 . PHE A 1 516 ? -27.731 -23.245 -15.428 1.00 104.03 ? 516 PHE A CD1 1 ATOM 3544 C CD2 . PHE A 1 516 ? -29.321 -22.804 -17.147 1.00 103.47 ? 516 PHE A CD2 1 ATOM 3545 C CE1 . PHE A 1 516 ? -26.889 -23.836 -16.354 1.00 94.41 ? 516 PHE A CE1 1 ATOM 3546 C CE2 . PHE A 1 516 ? -28.485 -23.393 -18.077 1.00 90.97 ? 516 PHE A CE2 1 ATOM 3547 C CZ . PHE A 1 516 ? -27.268 -23.910 -17.679 1.00 89.29 ? 516 PHE A CZ 1 ATOM 3548 N N . SER A 1 523 ? -26.036 -29.545 -8.245 1.00 103.01 ? 523 SER A N 1 ATOM 3549 C CA . SER A 1 523 ? -24.593 -29.691 -8.399 1.00 112.14 ? 523 SER A CA 1 ATOM 3550 C C . SER A 1 523 ? -24.223 -30.205 -9.790 1.00 110.31 ? 523 SER A C 1 ATOM 3551 O O . SER A 1 523 ? -23.249 -30.938 -9.955 1.00 106.40 ? 523 SER A O 1 ATOM 3552 C CB . SER A 1 523 ? -24.025 -30.613 -7.317 1.00 111.26 ? 523 SER A CB 1 ATOM 3553 O OG . SER A 1 523 ? -24.166 -30.037 -6.029 1.00 101.94 ? 523 SER A OG 1 ATOM 3554 N N . SER A 1 524 ? -25.013 -29.816 -10.786 1.00 110.91 ? 524 SER A N 1 ATOM 3555 C CA . SER A 1 524 ? -24.734 -30.152 -12.176 1.00 110.87 ? 524 SER A CA 1 ATOM 3556 C C . SER A 1 524 ? -24.584 -28.860 -12.964 1.00 103.13 ? 524 SER A C 1 ATOM 3557 O O . SER A 1 524 ? -23.515 -28.562 -13.496 1.00 93.43 ? 524 SER A O 1 ATOM 3558 C CB . SER A 1 524 ? -25.857 -31.010 -12.764 1.00 115.69 ? 524 SER A CB 1 ATOM 3559 O OG . SER A 1 524 ? -25.600 -31.333 -14.121 1.00 110.30 ? 524 SER A OG 1 ATOM 3560 N N . ARG A 1 525 ? -25.669 -28.095 -13.027 1.00 110.49 ? 525 ARG A N 1 ATOM 3561 C CA . ARG A 1 525 ? -25.661 -26.783 -13.661 1.00 105.11 ? 525 ARG A CA 1 ATOM 3562 C C . ARG A 1 525 ? -24.816 -25.793 -12.860 1.00 101.36 ? 525 ARG A C 1 ATOM 3563 O O . ARG A 1 525 ? -24.378 -24.770 -13.386 1.00 99.31 ? 525 ARG A O 1 ATOM 3564 C CB . ARG A 1 525 ? -27.082 -26.268 -13.813 1.00 98.92 ? 525 ARG A CB 1 ATOM 3565 N N . VAL A 1 526 ? -24.597 -26.106 -11.585 1.00 102.07 ? 526 VAL A N 1 ATOM 3566 C CA . VAL A 1 526 ? -23.783 -25.272 -10.707 1.00 94.80 ? 526 VAL A CA 1 ATOM 3567 C C . VAL A 1 526 ? -22.300 -25.451 -11.017 1.00 82.62 ? 526 VAL A C 1 ATOM 3568 O O . VAL A 1 526 ? -21.533 -24.487 -11.017 1.00 72.10 ? 526 VAL A O 1 ATOM 3569 C CB . VAL A 1 526 ? -24.031 -25.614 -9.225 1.00 95.44 ? 526 VAL A CB 1 ATOM 3570 C CG1 . VAL A 1 526 ? -23.366 -24.584 -8.320 1.00 82.13 ? 526 VAL A CG1 1 ATOM 3571 C CG2 . VAL A 1 526 ? -25.525 -25.702 -8.940 1.00 89.83 ? 526 VAL A CG2 1 ATOM 3572 N N . LEU A 1 527 ? -21.905 -26.693 -11.287 1.00 88.32 ? 527 LEU A N 1 ATOM 3573 C CA . LEU A 1 527 ? -20.517 -27.011 -11.610 1.00 84.22 ? 527 LEU A CA 1 ATOM 3574 C C . LEU A 1 527 ? -20.104 -26.447 -12.971 1.00 81.17 ? 527 LEU A C 1 ATOM 3575 O O . LEU A 1 527 ? -18.921 -26.416 -13.303 1.00 75.09 ? 527 LEU A O 1 ATOM 3576 C CB . LEU A 1 527 ? -20.277 -28.525 -11.556 1.00 84.86 ? 527 LEU A CB 1 ATOM 3577 C CG . LEU A 1 527 ? -20.448 -29.205 -10.195 1.00 86.29 ? 527 LEU A CG 1 ATOM 3578 C CD1 . LEU A 1 527 ? -20.009 -30.664 -10.246 1.00 91.57 ? 527 LEU A CD1 1 ATOM 3579 C CD2 . LEU A 1 527 ? -19.689 -28.455 -9.110 1.00 81.78 ? 527 LEU A CD2 1 ATOM 3580 N N . ASP A 1 528 ? -21.087 -26.003 -13.750 1.00 82.62 ? 528 ASP A N 1 ATOM 3581 C CA . ASP A 1 528 ? -20.830 -25.338 -15.022 1.00 78.96 ? 528 ASP A CA 1 ATOM 3582 C C . ASP A 1 528 ? -20.357 -23.906 -14.796 1.00 76.06 ? 528 ASP A C 1 ATOM 3583 O O . ASP A 1 528 ? -19.398 -23.453 -15.420 1.00 70.24 ? 528 ASP A O 1 ATOM 3584 C CB . ASP A 1 528 ? -22.094 -25.326 -15.886 1.00 83.30 ? 528 ASP A CB 1 ATOM 3585 C CG . ASP A 1 528 ? -22.448 -26.696 -16.425 1.00 89.55 ? 528 ASP A CG 1 ATOM 3586 O OD1 . ASP A 1 528 ? -22.087 -27.706 -15.786 1.00 92.30 ? 528 ASP A OD1 1 ATOM 3587 O OD2 . ASP A 1 528 ? -23.093 -26.759 -17.493 1.00 91.48 ? 528 ASP A OD2 1 ATOM 3588 N N . GLY A 1 529 ? -21.040 -23.199 -13.901 1.00 77.66 ? 529 GLY A N 1 ATOM 3589 C CA . GLY A 1 529 ? -20.723 -21.813 -13.608 1.00 73.27 ? 529 GLY A CA 1 ATOM 3590 C C . GLY A 1 529 ? -19.324 -21.616 -13.056 1.00 71.38 ? 529 GLY A C 1 ATOM 3591 O O . GLY A 1 529 ? -18.676 -20.610 -13.336 1.00 68.62 ? 529 GLY A O 1 ATOM 3592 N N . ARG A 1 530 ? -18.852 -22.587 -12.281 1.00 70.83 ? 530 ARG A N 1 ATOM 3593 C CA . ARG A 1 530 ? -17.540 -22.493 -11.653 1.00 61.66 ? 530 ARG A CA 1 ATOM 3594 C C . ARG A 1 530 ? -16.424 -22.713 -12.673 1.00 55.41 ? 530 ARG A C 1 ATOM 3595 O O . ARG A 1 530 ? -15.621 -21.814 -12.923 1.00 51.60 ? 530 ARG A O 1 ATOM 3596 C CB . ARG A 1 530 ? -17.421 -23.492 -10.495 1.00 61.85 ? 530 ARG A CB 1 ATOM 3597 C CG . ARG A 1 530 ? -18.589 -23.461 -9.514 1.00 65.74 ? 530 ARG A CG 1 ATOM 3598 C CD . ARG A 1 530 ? -18.458 -24.526 -8.430 1.00 67.38 ? 530 ARG A CD 1 ATOM 3599 N NE . ARG A 1 530 ? -17.981 -23.975 -7.164 1.00 63.73 ? 530 ARG A NE 1 ATOM 3600 C CZ . ARG A 1 530 ? -16.720 -24.031 -6.752 1.00 68.93 ? 530 ARG A CZ 1 ATOM 3601 N NH1 . ARG A 1 530 ? -15.801 -24.618 -7.503 1.00 74.39 ? 530 ARG A NH1 1 ATOM 3602 N NH2 . ARG A 1 530 ? -16.379 -23.501 -5.587 1.00 70.39 ? 530 ARG A NH2 1 ATOM 3603 N N . THR A 1 531 ? -16.380 -23.909 -13.254 1.00 54.10 ? 531 THR A N 1 ATOM 3604 C CA . THR A 1 531 ? -15.329 -24.279 -14.200 1.00 57.09 ? 531 THR A CA 1 ATOM 3605 C C . THR A 1 531 ? -15.205 -23.312 -15.381 1.00 58.32 ? 531 THR A C 1 ATOM 3606 O O . THR A 1 531 ? -14.115 -23.122 -15.920 1.00 51.36 ? 531 THR A O 1 ATOM 3607 C CB . THR A 1 531 ? -15.513 -25.731 -14.720 1.00 59.51 ? 531 THR A CB 1 ATOM 3608 O OG1 . THR A 1 531 ? -14.389 -26.106 -15.526 1.00 62.17 ? 531 THR A OG1 1 ATOM 3609 C CG2 . THR A 1 531 ? -16.782 -25.857 -15.545 1.00 74.19 ? 531 THR A CG2 1 ATOM 3610 N N . THR A 1 532 ? -16.317 -22.697 -15.773 1.00 67.91 ? 532 THR A N 1 ATOM 3611 C CA . THR A 1 532 ? -16.294 -21.737 -16.873 1.00 69.42 ? 532 THR A CA 1 ATOM 3612 C C . THR A 1 532 ? -15.858 -20.349 -16.399 1.00 63.12 ? 532 THR A C 1 ATOM 3613 O O . THR A 1 532 ? -15.476 -19.505 -17.208 1.00 60.84 ? 532 THR A O 1 ATOM 3614 C CB . THR A 1 532 ? -17.654 -21.659 -17.613 1.00 60.24 ? 532 THR A CB 1 ATOM 3615 O OG1 . THR A 1 532 ? -18.701 -21.372 -16.678 1.00 58.11 ? 532 THR A OG1 1 ATOM 3616 C CG2 . THR A 1 532 ? -17.956 -22.978 -18.318 1.00 49.19 ? 532 THR A CG2 1 ATOM 3617 N N . LEU A 1 533 ? -15.904 -20.121 -15.089 1.00 56.01 ? 533 LEU A N 1 ATOM 3618 C CA . LEU A 1 533 ? -15.411 -18.869 -14.520 1.00 57.04 ? 533 LEU A CA 1 ATOM 3619 C C . LEU A 1 533 ? -13.884 -18.865 -14.484 1.00 63.74 ? 533 LEU A C 1 ATOM 3620 O O . LEU A 1 533 ? -13.250 -17.822 -14.653 1.00 59.31 ? 533 LEU A O 1 ATOM 3621 C CB . LEU A 1 533 ? -16.002 -18.625 -13.127 1.00 44.07 ? 533 LEU A CB 1 ATOM 3622 C CG . LEU A 1 533 ? -17.279 -17.781 -13.085 1.00 35.82 ? 533 LEU A CG 1 ATOM 3623 C CD1 . LEU A 1 533 ? -17.924 -17.828 -11.714 1.00 43.54 ? 533 LEU A CD1 1 ATOM 3624 C CD2 . LEU A 1 533 ? -16.976 -16.348 -13.467 1.00 33.94 ? 533 LEU A CD2 1 ATOM 3625 N N . LEU A 1 534 ? -13.305 -20.042 -14.263 1.00 64.10 ? 534 LEU A N 1 ATOM 3626 C CA . LEU A 1 534 ? -11.867 -20.240 -14.393 1.00 57.07 ? 534 LEU A CA 1 ATOM 3627 C C . LEU A 1 534 ? -11.437 -19.928 -15.818 1.00 60.45 ? 534 LEU A C 1 ATOM 3628 O O . LEU A 1 534 ? -10.529 -19.129 -16.049 1.00 62.91 ? 534 LEU A O 1 ATOM 3629 C CB . LEU A 1 534 ? -11.508 -21.694 -14.088 1.00 52.27 ? 534 LEU A CB 1 ATOM 3630 C CG . LEU A 1 534 ? -11.293 -22.158 -12.651 1.00 48.18 ? 534 LEU A CG 1 ATOM 3631 C CD1 . LEU A 1 534 ? -10.873 -23.619 -12.647 1.00 43.34 ? 534 LEU A CD1 1 ATOM 3632 C CD2 . LEU A 1 534 ? -10.244 -21.299 -11.981 1.00 53.69 ? 534 LEU A CD2 1 ATOM 3633 N N . LEU A 1 535 ? -12.108 -20.575 -16.767 1.00 57.21 ? 535 LEU A N 1 ATOM 3634 C CA . LEU A 1 535 ? -11.776 -20.476 -18.183 1.00 54.49 ? 535 LEU A CA 1 ATOM 3635 C C . LEU A 1 535 ? -11.820 -19.039 -18.692 1.00 58.23 ? 535 LEU A C 1 ATOM 3636 O O . LEU A 1 535 ? -10.948 -18.617 -19.448 1.00 59.09 ? 535 LEU A O 1 ATOM 3637 C CB . LEU A 1 535 ? -12.710 -21.369 -19.002 1.00 51.57 ? 535 LEU A CB 1 ATOM 3638 C CG . LEU A 1 535 ? -12.583 -22.865 -18.707 1.00 51.91 ? 535 LEU A CG 1 ATOM 3639 C CD1 . LEU A 1 535 ? -13.791 -23.639 -19.213 1.00 68.27 ? 535 LEU A CD1 1 ATOM 3640 C CD2 . LEU A 1 535 ? -11.303 -23.421 -19.310 1.00 57.52 ? 535 LEU A CD2 1 ATOM 3641 N N . MET A 1 536 ? -12.835 -18.291 -18.272 1.00 59.86 ? 536 MET A N 1 ATOM 3642 C CA . MET A 1 536 ? -12.945 -16.882 -18.635 1.00 63.45 ? 536 MET A CA 1 ATOM 3643 C C . MET A 1 536 ? -11.845 -16.066 -17.956 1.00 61.28 ? 536 MET A C 1 ATOM 3644 O O . MET A 1 536 ? -11.273 -15.153 -18.555 1.00 59.46 ? 536 MET A O 1 ATOM 3645 C CB . MET A 1 536 ? -14.324 -16.331 -18.262 1.00 60.47 ? 536 MET A CB 1 ATOM 3646 C CG . MET A 1 536 ? -15.490 -16.969 -19.007 1.00 62.44 ? 536 MET A CG 1 ATOM 3647 S SD . MET A 1 536 ? -15.496 -16.617 -20.776 1.00 79.82 ? 536 MET A SD 1 ATOM 3648 C CE . MET A 1 536 ? -15.989 -14.895 -20.775 1.00 60.27 ? 536 MET A CE 1 ATOM 3649 N N . THR A 1 537 ? -11.548 -16.408 -16.704 1.00 62.50 ? 537 THR A N 1 ATOM 3650 C CA . THR A 1 537 ? -10.488 -15.747 -15.950 1.00 62.98 ? 537 THR A CA 1 ATOM 3651 C C . THR A 1 537 ? -9.122 -16.042 -16.561 1.00 57.44 ? 537 THR A C 1 ATOM 3652 O O . THR A 1 537 ? -8.315 -15.134 -16.767 1.00 52.17 ? 537 THR A O 1 ATOM 3653 C CB . THR A 1 537 ? -10.487 -16.197 -14.472 1.00 62.71 ? 537 THR A CB 1 ATOM 3654 O OG1 . THR A 1 537 ? -11.804 -16.051 -13.922 1.00 52.64 ? 537 THR A OG1 1 ATOM 3655 C CG2 . THR A 1 537 ? -9.505 -15.370 -13.658 1.00 60.64 ? 537 THR A CG2 1 ATOM 3656 N N . SER A 1 538 ? -8.882 -17.317 -16.857 1.00 59.93 ? 538 SER A N 1 ATOM 3657 C CA . SER A 1 538 ? -7.608 -17.776 -17.401 1.00 61.20 ? 538 SER A CA 1 ATOM 3658 C C . SER A 1 538 ? -7.250 -17.111 -18.728 1.00 64.85 ? 538 SER A C 1 ATOM 3659 O O . SER A 1 538 ? -6.098 -16.732 -18.945 1.00 62.95 ? 538 SER A O 1 ATOM 3660 C CB . SER A 1 538 ? -7.614 -19.298 -17.563 1.00 60.73 ? 538 SER A CB 1 ATOM 3661 O OG . SER A 1 538 ? -6.402 -19.756 -18.140 1.00 61.36 ? 538 SER A OG 1 ATOM 3662 N N . MET A 1 539 ? -8.236 -16.971 -19.610 1.00 66.59 ? 539 MET A N 1 ATOM 3663 C CA . MET A 1 539 ? -8.024 -16.310 -20.896 1.00 64.95 ? 539 MET A CA 1 ATOM 3664 C C . MET A 1 539 ? -7.655 -14.847 -20.706 1.00 66.28 ? 539 MET A C 1 ATOM 3665 O O . MET A 1 539 ? -7.070 -14.226 -21.595 1.00 65.31 ? 539 MET A O 1 ATOM 3666 C CB . MET A 1 539 ? -9.270 -16.388 -21.773 1.00 61.88 ? 539 MET A CB 1 ATOM 3667 C CG . MET A 1 539 ? -9.688 -17.774 -22.192 1.00 61.97 ? 539 MET A CG 1 ATOM 3668 S SD . MET A 1 539 ? -11.204 -17.697 -23.161 1.00 68.83 ? 539 MET A SD 1 ATOM 3669 C CE . MET A 1 539 ? -11.999 -19.218 -22.659 1.00 65.86 ? 539 MET A CE 1 ATOM 3670 N N . CYS A 1 540 ? -7.988 -14.295 -19.545 1.00 63.13 ? 540 CYS A N 1 ATOM 3671 C CA . CYS A 1 540 ? -7.639 -12.914 -19.284 1.00 61.17 ? 540 CYS A CA 1 ATOM 3672 C C . CYS A 1 540 ? -6.248 -12.918 -18.684 1.00 66.80 ? 540 CYS A C 1 ATOM 3673 O O . CYS A 1 540 ? -6.036 -13.380 -17.563 1.00 68.15 ? 540 CYS A O 1 ATOM 3674 C CB . CYS A 1 540 ? -8.634 -12.270 -18.319 1.00 53.74 ? 540 CYS A CB 1 ATOM 3675 S SG . CYS A 1 540 ? -8.320 -10.522 -17.993 1.00 55.92 ? 540 CYS A SG 1 ATOM 3676 N N . THR A 1 541 ? -5.303 -12.398 -19.456 1.00 70.39 ? 541 THR A N 1 ATOM 3677 C CA . THR A 1 541 ? -3.912 -12.331 -19.055 1.00 67.03 ? 541 THR A CA 1 ATOM 3678 C C . THR A 1 541 ? -3.519 -10.872 -19.162 1.00 65.88 ? 541 THR A C 1 ATOM 3679 O O . THR A 1 541 ? -4.170 -10.109 -19.877 1.00 71.52 ? 541 THR A O 1 ATOM 3680 C CB . THR A 1 541 ? -3.016 -13.164 -19.994 1.00 68.12 ? 541 THR A CB 1 ATOM 3681 O OG1 . THR A 1 541 ? -2.776 -12.435 -21.205 1.00 72.41 ? 541 THR A OG1 1 ATOM 3682 C CG2 . THR A 1 541 ? -3.675 -14.499 -20.329 1.00 67.20 ? 541 THR A CG2 1 ATOM 3683 N N . ALA A 1 542 ? -2.466 -10.476 -18.456 1.00 58.09 ? 542 ALA A N 1 ATOM 3684 C CA . ALA A 1 542 ? -2.002 -9.097 -18.515 1.00 58.54 ? 542 ALA A CA 1 ATOM 3685 C C . ALA A 1 542 ? -1.655 -8.730 -19.951 1.00 66.27 ? 542 ALA A C 1 ATOM 3686 O O . ALA A 1 542 ? -1.760 -7.570 -20.348 1.00 69.79 ? 542 ALA A O 1 ATOM 3687 C CB . ALA A 1 542 ? -0.807 -8.901 -17.612 1.00 66.26 ? 542 ALA A CB 1 ATOM 3688 N N . ALA A 1 543 ? -1.255 -9.734 -20.726 1.00 70.85 ? 543 ALA A N 1 ATOM 3689 C CA . ALA A 1 543 ? -0.959 -9.552 -22.140 1.00 76.99 ? 543 ALA A CA 1 ATOM 3690 C C . ALA A 1 543 ? -2.229 -9.352 -22.971 1.00 71.64 ? 543 ALA A C 1 ATOM 3691 O O . ALA A 1 543 ? -2.276 -8.471 -23.830 1.00 70.13 ? 543 ALA A O 1 ATOM 3692 C CB . ALA A 1 543 ? -0.154 -10.736 -22.668 1.00 75.67 ? 543 ALA A CB 1 ATOM 3693 N N . HIS A 1 544 ? -3.256 -10.159 -22.711 1.00 71.12 ? 544 HIS A N 1 ATOM 3694 C CA . HIS A 1 544 ? -4.498 -10.087 -23.483 1.00 72.94 ? 544 HIS A CA 1 ATOM 3695 C C . HIS A 1 544 ? -5.402 -8.924 -23.078 1.00 70.43 ? 544 HIS A C 1 ATOM 3696 O O . HIS A 1 544 ? -5.997 -8.268 -23.934 1.00 68.28 ? 544 HIS A O 1 ATOM 3697 C CB . HIS A 1 544 ? -5.283 -11.398 -23.394 1.00 69.55 ? 544 HIS A CB 1 ATOM 3698 C CG . HIS A 1 544 ? -6.616 -11.346 -24.078 1.00 76.11 ? 544 HIS A CG 1 ATOM 3699 N ND1 . HIS A 1 544 ? -6.747 -11.308 -25.449 1.00 76.28 ? 544 HIS A ND1 1 ATOM 3700 C CD2 . HIS A 1 544 ? -7.875 -11.309 -23.579 1.00 70.89 ? 544 HIS A CD2 1 ATOM 3701 C CE1 . HIS A 1 544 ? -8.029 -11.256 -25.767 1.00 67.75 ? 544 HIS A CE1 1 ATOM 3702 N NE2 . HIS A 1 544 ? -8.734 -11.255 -24.650 1.00 65.49 ? 544 HIS A NE2 1 ATOM 3703 N N . ALA A 1 545 ? -5.510 -8.680 -21.775 1.00 69.35 ? 545 ALA A N 1 ATOM 3704 C CA . ALA A 1 545 ? -6.389 -7.634 -21.256 1.00 67.41 ? 545 ALA A CA 1 ATOM 3705 C C . ALA A 1 545 ? -6.073 -6.271 -21.863 1.00 71.49 ? 545 ALA A C 1 ATOM 3706 O O . ALA A 1 545 ? -6.974 -5.474 -22.125 1.00 75.06 ? 545 ALA A O 1 ATOM 3707 C CB . ALA A 1 545 ? -6.307 -7.573 -19.737 1.00 61.54 ? 545 ALA A CB 1 ATOM 3708 N N . THR A 1 546 ? -4.789 -6.016 -22.095 1.00 70.61 ? 546 THR A N 1 ATOM 3709 C CA . THR A 1 546 ? -4.355 -4.765 -22.703 1.00 72.74 ? 546 THR A CA 1 ATOM 3710 C C . THR A 1 546 ? -4.791 -4.670 -24.166 1.00 74.87 ? 546 THR A C 1 ATOM 3711 O O . THR A 1 546 ? -4.918 -3.575 -24.711 1.00 75.94 ? 546 THR A O 1 ATOM 3712 C CB . THR A 1 546 ? -2.827 -4.592 -22.607 1.00 76.09 ? 546 THR A CB 1 ATOM 3713 O OG1 . THR A 1 546 ? -2.180 -5.723 -23.203 1.00 83.20 ? 546 THR A OG1 1 ATOM 3714 C CG2 . THR A 1 546 ? -2.394 -4.474 -21.152 1.00 69.82 ? 546 THR A CG2 1 ATOM 3715 N N . GLN A 1 547 ? -5.010 -5.820 -24.797 1.00 72.05 ? 547 GLN A N 1 ATOM 3716 C CA . GLN A 1 547 ? -5.529 -5.854 -26.161 1.00 72.90 ? 547 GLN A CA 1 ATOM 3717 C C . GLN A 1 547 ? -7.036 -5.622 -26.167 1.00 74.52 ? 547 GLN A C 1 ATOM 3718 O O . GLN A 1 547 ? -7.558 -4.887 -27.005 1.00 78.00 ? 547 GLN A O 1 ATOM 3719 C CB . GLN A 1 547 ? -5.208 -7.192 -26.839 1.00 72.20 ? 547 GLN A CB 1 ATOM 3720 C CG . GLN A 1 547 ? -3.761 -7.356 -27.298 1.00 77.50 ? 547 GLN A CG 1 ATOM 3721 C CD . GLN A 1 547 ? -3.464 -6.629 -28.600 1.00 78.64 ? 547 GLN A CD 1 ATOM 3722 O OE1 . GLN A 1 547 ? -4.264 -5.820 -29.072 1.00 76.64 ? 547 GLN A OE1 1 ATOM 3723 N NE2 . GLN A 1 547 ? -2.309 -6.920 -29.189 1.00 74.28 ? 547 GLN A NE2 1 ATOM 3724 N N . ALA A 1 548 ? -7.725 -6.252 -25.220 1.00 71.60 ? 548 ALA A N 1 ATOM 3725 C CA . ALA A 1 548 ? -9.180 -6.191 -25.140 1.00 67.72 ? 548 ALA A CA 1 ATOM 3726 C C . ALA A 1 548 ? -9.679 -4.820 -24.699 1.00 66.65 ? 548 ALA A C 1 ATOM 3727 O O . ALA A 1 548 ? -10.634 -4.286 -25.265 1.00 64.43 ? 548 ALA A O 1 ATOM 3728 C CB . ALA A 1 548 ? -9.693 -7.263 -24.205 1.00 61.74 ? 548 ALA A CB 1 ATOM 3729 N N . ALA A 1 549 ? -9.035 -4.257 -23.682 1.00 66.35 ? 549 ALA A N 1 ATOM 3730 C CA . ALA A 1 549 ? -9.378 -2.921 -23.208 1.00 65.93 ? 549 ALA A CA 1 ATOM 3731 C C . ALA A 1 549 ? -9.034 -1.877 -24.264 1.00 71.42 ? 549 ALA A C 1 ATOM 3732 O O . ALA A 1 549 ? -9.554 -0.762 -24.244 1.00 70.26 ? 549 ALA A O 1 ATOM 3733 C CB . ALA A 1 549 ? -8.655 -2.617 -21.910 1.00 67.08 ? 549 ALA A CB 1 ATOM 3734 N N . LEU A 1 550 ? -8.147 -2.250 -25.181 1.00 72.86 ? 550 LEU A N 1 ATOM 3735 C CA . LEU A 1 550 ? -7.784 -1.391 -26.300 1.00 72.96 ? 550 LEU A CA 1 ATOM 3736 C C . LEU A 1 550 ? -8.878 -1.429 -27.367 1.00 76.75 ? 550 LEU A C 1 ATOM 3737 O O . LEU A 1 550 ? -9.187 -0.408 -27.984 1.00 77.76 ? 550 LEU A O 1 ATOM 3738 C CB . LEU A 1 550 ? -6.439 -1.827 -26.885 1.00 70.04 ? 550 LEU A CB 1 ATOM 3739 C CG . LEU A 1 550 ? -5.378 -0.745 -27.091 1.00 75.13 ? 550 LEU A CG 1 ATOM 3740 C CD1 . LEU A 1 550 ? -5.356 0.211 -25.917 1.00 76.35 ? 550 LEU A CD1 1 ATOM 3741 C CD2 . LEU A 1 550 ? -4.008 -1.377 -27.282 1.00 86.15 ? 550 LEU A CD2 1 ATOM 3742 N N . ASN A 1 551 ? -9.459 -2.610 -27.574 1.00 73.42 ? 551 ASN A N 1 ATOM 3743 C CA . ASN A 1 551 ? -10.576 -2.775 -28.502 1.00 67.36 ? 551 ASN A CA 1 ATOM 3744 C C . ASN A 1 551 ? -11.746 -1.877 -28.121 1.00 67.81 ? 551 ASN A C 1 ATOM 3745 O O . ASN A 1 551 ? -12.301 -1.168 -28.963 1.00 68.51 ? 551 ASN A O 1 ATOM 3746 C CB . ASN A 1 551 ? -11.052 -4.231 -28.528 1.00 62.74 ? 551 ASN A CB 1 ATOM 3747 C CG . ASN A 1 551 ? -9.948 -5.209 -28.878 1.00 66.34 ? 551 ASN A CG 1 ATOM 3748 O OD1 . ASN A 1 551 ? -8.961 -4.849 -29.518 1.00 70.72 ? 551 ASN A OD1 1 ATOM 3749 N ND2 . ASN A 1 551 ? -10.116 -6.460 -28.463 1.00 64.44 ? 551 ASN A ND2 1 ATOM 3750 N N . ILE A 1 552 ? -12.111 -1.922 -26.841 1.00 63.71 ? 552 ILE A N 1 ATOM 3751 C CA . ILE A 1 552 ? -13.209 -1.126 -26.303 1.00 59.96 ? 552 ILE A CA 1 ATOM 3752 C C . ILE A 1 552 ? -12.970 0.369 -26.516 1.00 65.93 ? 552 ILE A C 1 ATOM 3753 O O . ILE A 1 552 ? -13.897 1.115 -26.825 1.00 68.77 ? 552 ILE A O 1 ATOM 3754 C CB . ILE A 1 552 ? -13.427 -1.411 -24.797 1.00 58.21 ? 552 ILE A CB 1 ATOM 3755 C CG1 . ILE A 1 552 ? -13.688 -2.902 -24.560 1.00 57.40 ? 552 ILE A CG1 1 ATOM 3756 C CG2 . ILE A 1 552 ? -14.578 -0.586 -24.246 1.00 62.18 ? 552 ILE A CG2 1 ATOM 3757 C CD1 . ILE A 1 552 ? -14.014 -3.248 -23.116 1.00 52.65 ? 552 ILE A CD1 1 ATOM 3758 N N . GLN A 1 553 ? -11.720 0.798 -26.363 1.00 67.86 ? 553 GLN A N 1 ATOM 3759 C CA . GLN A 1 553 ? -11.372 2.205 -26.553 1.00 70.59 ? 553 GLN A CA 1 ATOM 3760 C C . GLN A 1 553 ? -11.357 2.613 -28.026 1.00 73.91 ? 553 GLN A C 1 ATOM 3761 O O . GLN A 1 553 ? -11.683 3.753 -28.359 1.00 76.30 ? 553 GLN A O 1 ATOM 3762 C CB . GLN A 1 553 ? -10.032 2.542 -25.889 1.00 69.35 ? 553 GLN A CB 1 ATOM 3763 C CG . GLN A 1 553 ? -10.144 2.887 -24.409 1.00 70.03 ? 553 GLN A CG 1 ATOM 3764 C CD . GLN A 1 553 ? -8.901 3.573 -23.870 1.00 74.38 ? 553 GLN A CD 1 ATOM 3765 O OE1 . GLN A 1 553 ? -7.783 3.091 -24.052 1.00 78.58 ? 553 GLN A OE1 1 ATOM 3766 N NE2 . GLN A 1 553 ? -9.092 4.708 -23.208 1.00 79.26 ? 553 GLN A NE2 1 ATOM 3767 N N . GLU A 1 554 ? -10.977 1.689 -28.904 1.00 71.74 ? 554 GLU A N 1 ATOM 3768 C CA . GLU A 1 554 ? -11.013 1.959 -30.337 1.00 77.98 ? 554 GLU A CA 1 ATOM 3769 C C . GLU A 1 554 ? -12.457 1.954 -30.825 1.00 74.84 ? 554 GLU A C 1 ATOM 3770 O O . GLU A 1 554 ? -12.836 2.748 -31.686 1.00 77.56 ? 554 GLU A O 1 ATOM 3771 C CB . GLU A 1 554 ? -10.177 0.937 -31.119 1.00 83.36 ? 554 GLU A CB 1 ATOM 3772 C CG . GLU A 1 554 ? -10.102 1.218 -32.621 1.00 93.39 ? 554 GLU A CG 1 ATOM 3773 C CD . GLU A 1 554 ? -9.246 0.214 -33.379 1.00 96.31 ? 554 GLU A CD 1 ATOM 3774 O OE1 . GLU A 1 554 ? -8.613 -0.647 -32.732 1.00 93.32 ? 554 GLU A OE1 1 ATOM 3775 O OE2 . GLU A 1 554 ? -9.208 0.288 -34.626 1.00 98.69 ? 554 GLU A OE2 1 ATOM 3776 N N . GLY A 1 555 ? -13.262 1.060 -30.259 1.00 69.93 ? 555 GLY A N 1 ATOM 3777 C CA . GLY A 1 555 ? -14.662 0.952 -30.624 1.00 78.07 ? 555 GLY A CA 1 ATOM 3778 C C . GLY A 1 555 ? -15.481 2.177 -30.259 1.00 84.99 ? 555 GLY A C 1 ATOM 3779 O O . GLY A 1 555 ? -16.371 2.578 -31.007 1.00 92.74 ? 555 GLY A O 1 ATOM 3780 N N . LEU A 1 556 ? -15.187 2.769 -29.105 1.00 82.17 ? 556 LEU A N 1 ATOM 3781 C CA . LEU A 1 556 ? -15.917 3.945 -28.639 1.00 77.56 ? 556 LEU A CA 1 ATOM 3782 C C . LEU A 1 556 ? -15.447 5.229 -29.320 1.00 82.83 ? 556 LEU A C 1 ATOM 3783 O O . LEU A 1 556 ? -16.225 6.168 -29.492 1.00 82.72 ? 556 LEU A O 1 ATOM 3784 C CB . LEU A 1 556 ? -15.812 4.084 -27.117 1.00 76.44 ? 556 LEU A CB 1 ATOM 3785 C CG . LEU A 1 556 ? -16.467 2.978 -26.286 1.00 79.30 ? 556 LEU A CG 1 ATOM 3786 C CD1 . LEU A 1 556 ? -16.340 3.259 -24.794 1.00 79.97 ? 556 LEU A CD1 1 ATOM 3787 C CD2 . LEU A 1 556 ? -17.922 2.816 -26.681 1.00 77.06 ? 556 LEU A CD2 1 ATOM 3788 N N . ALA A 1 557 ? -14.174 5.268 -29.701 1.00 83.49 ? 557 ALA A N 1 ATOM 3789 C CA . ALA A 1 557 ? -13.602 6.445 -30.350 1.00 80.42 ? 557 ALA A CA 1 ATOM 3790 C C . ALA A 1 557 ? -14.017 6.547 -31.815 1.00 87.46 ? 557 ALA A C 1 ATOM 3791 O O . ALA A 1 557 ? -14.247 7.641 -32.329 1.00 89.55 ? 557 ALA A O 1 ATOM 3792 C CB . ALA A 1 557 ? -12.088 6.439 -30.226 1.00 74.39 ? 557 ALA A CB 1 ATOM 3793 N N . TYR A 1 558 ? -14.102 5.402 -32.485 1.00 87.68 ? 558 TYR A N 1 ATOM 3794 C CA . TYR A 1 558 ? -14.526 5.366 -33.881 1.00 90.36 ? 558 TYR A CA 1 ATOM 3795 C C . TYR A 1 558 ? -16.027 5.115 -34.018 1.00 91.56 ? 558 TYR A C 1 ATOM 3796 O O . TYR A 1 558 ? -16.544 4.975 -35.125 1.00 95.71 ? 558 TYR A O 1 ATOM 3797 C CB . TYR A 1 558 ? -13.724 4.327 -34.669 1.00 94.43 ? 558 TYR A CB 1 ATOM 3798 C CG . TYR A 1 558 ? -12.318 4.779 -34.991 1.00 104.20 ? 558 TYR A CG 1 ATOM 3799 C CD1 . TYR A 1 558 ? -12.092 5.777 -35.928 1.00 112.53 ? 558 TYR A CD1 1 ATOM 3800 C CD2 . TYR A 1 558 ? -11.219 4.210 -34.361 1.00 97.92 ? 558 TYR A CD2 1 ATOM 3801 C CE1 . TYR A 1 558 ? -10.815 6.199 -36.228 1.00 119.03 ? 558 TYR A CE1 1 ATOM 3802 C CE2 . TYR A 1 558 ? -9.934 4.626 -34.657 1.00 100.86 ? 558 TYR A CE2 1 ATOM 3803 C CZ . TYR A 1 558 ? -9.740 5.621 -35.591 1.00 110.62 ? 558 TYR A CZ 1 ATOM 3804 O OH . TYR A 1 558 ? -8.470 6.045 -35.896 1.00 117.86 ? 558 TYR A OH 1 ATOM 3805 N N . LEU A 1 559 ? -16.714 5.057 -32.881 1.00 95.04 ? 559 LEU A N 1 ATOM 3806 C CA . LEU A 1 559 ? -18.160 4.859 -32.850 1.00 93.55 ? 559 LEU A CA 1 ATOM 3807 C C . LEU A 1 559 ? -18.929 5.980 -33.544 1.00 93.19 ? 559 LEU A C 1 ATOM 3808 O O . LEU A 1 559 ? -18.709 7.160 -33.272 1.00 97.24 ? 559 LEU A O 1 ATOM 3809 C CB . LEU A 1 559 ? -18.642 4.740 -31.400 1.00 90.31 ? 559 LEU A CB 1 ATOM 3810 C CG . LEU A 1 559 ? -20.110 5.067 -31.106 1.00 93.43 ? 559 LEU A CG 1 ATOM 3811 C CD1 . LEU A 1 559 ? -21.044 4.009 -31.678 1.00 91.04 ? 559 LEU A CD1 1 ATOM 3812 C CD2 . LEU A 1 559 ? -20.339 5.244 -29.608 1.00 84.09 ? 559 LEU A CD2 1 ATOM 3813 N N . ASN A 1 560 ? -19.826 5.598 -34.448 1.00 82.86 ? 560 ASN A N 1 ATOM 3814 C CA . ASN A 1 560 ? -20.815 6.524 -34.982 1.00 80.43 ? 560 ASN A CA 1 ATOM 3815 C C . ASN A 1 560 ? -22.201 6.057 -34.560 1.00 82.06 ? 560 ASN A C 1 ATOM 3816 O O . ASN A 1 560 ? -22.678 5.020 -35.019 1.00 82.21 ? 560 ASN A O 1 ATOM 3817 C CB . ASN A 1 560 ? -20.724 6.617 -36.507 1.00 86.12 ? 560 ASN A CB 1 ATOM 3818 C CG . ASN A 1 560 ? -21.519 7.787 -37.073 1.00 84.69 ? 560 ASN A CG 1 ATOM 3819 O OD1 . ASN A 1 560 ? -22.476 8.263 -36.462 1.00 81.93 ? 560 ASN A OD1 1 ATOM 3820 N ND2 . ASN A 1 560 ? -21.123 8.252 -38.252 1.00 94.42 ? 560 ASN A ND2 1 ATOM 3821 N N . PRO A 1 561 ? -22.845 6.818 -33.666 1.00 84.05 ? 561 PRO A N 1 ATOM 3822 C CA . PRO A 1 561 ? -24.176 6.485 -33.147 1.00 77.46 ? 561 PRO A CA 1 ATOM 3823 C C . PRO A 1 561 ? -25.243 6.535 -34.234 1.00 72.16 ? 561 PRO A C 1 ATOM 3824 O O . PRO A 1 561 ? -26.138 5.691 -34.265 1.00 64.22 ? 561 PRO A O 1 ATOM 3825 C CB . PRO A 1 561 ? -24.428 7.584 -32.112 1.00 80.05 ? 561 PRO A CB 1 ATOM 3826 C CG . PRO A 1 561 ? -23.565 8.721 -32.540 1.00 82.97 ? 561 PRO A CG 1 ATOM 3827 C CD . PRO A 1 561 ? -22.340 8.091 -33.123 1.00 83.83 ? 561 PRO A CD 1 ATOM 3828 N N . SER A 1 562 ? -25.135 7.524 -35.114 1.00 75.95 ? 562 SER A N 1 ATOM 3829 C CA . SER A 1 562 ? -26.128 7.753 -36.156 1.00 75.23 ? 562 SER A CA 1 ATOM 3830 C C . SER A 1 562 ? -26.122 6.696 -37.258 1.00 77.29 ? 562 SER A C 1 ATOM 3831 O O . SER A 1 562 ? -27.173 6.171 -37.619 1.00 75.10 ? 562 SER A O 1 ATOM 3832 C CB . SER A 1 562 ? -25.940 9.143 -36.776 1.00 78.97 ? 562 SER A CB 1 ATOM 3833 O OG . SER A 1 562 ? -26.182 10.168 -35.826 1.00 76.64 ? 562 SER A OG 1 ATOM 3834 N N . LYS A 1 563 ? -24.950 6.419 -37.823 1.00 77.29 ? 563 LYS A N 1 ATOM 3835 C CA . LYS A 1 563 ? -24.867 5.498 -38.958 1.00 78.90 ? 563 LYS A CA 1 ATOM 3836 C C . LYS A 1 563 ? -24.446 4.046 -38.692 1.00 69.41 ? 563 LYS A C 1 ATOM 3837 O O . LYS A 1 563 ? -24.416 3.244 -39.617 1.00 71.41 ? 563 LYS A O 1 ATOM 3838 C CB . LYS A 1 563 ? -24.063 6.108 -40.115 1.00 79.61 ? 563 LYS A CB 1 ATOM 3839 C CG . LYS A 1 563 ? -24.899 7.018 -41.008 1.00 85.86 ? 563 LYS A CG 1 ATOM 3840 C CD . LYS A 1 563 ? -26.277 6.404 -41.254 1.00 82.95 ? 563 LYS A CD 1 ATOM 3841 C CE . LYS A 1 563 ? -27.207 7.340 -42.013 1.00 89.94 ? 563 LYS A CE 1 ATOM 3842 N NZ . LYS A 1 563 ? -27.005 7.269 -43.487 1.00 98.68 ? 563 LYS A NZ 1 ATOM 3843 N N . HIS A 1 564 ? -24.132 3.695 -37.450 1.00 63.49 ? 564 HIS A N 1 ATOM 3844 C CA . HIS A 1 564 ? -23.768 2.307 -37.157 1.00 59.07 ? 564 HIS A CA 1 ATOM 3845 C C . HIS A 1 564 ? -24.196 1.840 -35.767 1.00 60.42 ? 564 HIS A C 1 ATOM 3846 O O . HIS A 1 564 ? -24.242 2.629 -34.824 1.00 62.56 ? 564 HIS A O 1 ATOM 3847 C CB . HIS A 1 564 ? -22.266 2.080 -37.358 1.00 71.78 ? 564 HIS A CB 1 ATOM 3848 C CG . HIS A 1 564 ? -21.841 2.069 -38.794 1.00 72.34 ? 564 HIS A CG 1 ATOM 3849 N ND1 . HIS A 1 564 ? -21.492 3.215 -39.477 1.00 72.71 ? 564 HIS A ND1 1 ATOM 3850 C CD2 . HIS A 1 564 ? -21.715 1.052 -39.679 1.00 70.51 ? 564 HIS A CD2 1 ATOM 3851 C CE1 . HIS A 1 564 ? -21.165 2.904 -40.718 1.00 72.37 ? 564 HIS A CE1 1 ATOM 3852 N NE2 . HIS A 1 564 ? -21.292 1.597 -40.867 1.00 73.97 ? 564 HIS A NE2 1 ATOM 3853 N N . MET A 1 565 ? -24.506 0.551 -35.646 1.00 55.69 ? 565 MET A N 1 ATOM 3854 C CA . MET A 1 565 ? -24.975 -0.005 -34.379 1.00 53.96 ? 565 MET A CA 1 ATOM 3855 C C . MET A 1 565 ? -23.822 -0.424 -33.476 1.00 45.10 ? 565 MET A C 1 ATOM 3856 O O . MET A 1 565 ? -23.021 -1.283 -33.842 1.00 45.53 ? 565 MET A O 1 ATOM 3857 C CB . MET A 1 565 ? -25.884 -1.215 -34.617 1.00 56.42 ? 565 MET A CB 1 ATOM 3858 C CG . MET A 1 565 ? -26.831 -1.517 -33.456 1.00 53.73 ? 565 MET A CG 1 ATOM 3859 S SD . MET A 1 565 ? -27.312 -3.252 -33.337 1.00 63.71 ? 565 MET A SD 1 ATOM 3860 C CE . MET A 1 565 ? -27.480 -3.665 -35.072 1.00 62.61 ? 565 MET A CE 1 ATOM 3861 N N . PHE A 1 566 ? -23.742 0.176 -32.293 1.00 43.15 ? 566 PHE A N 1 ATOM 3862 C CA . PHE A 1 566 ? -22.791 -0.287 -31.288 1.00 43.78 ? 566 PHE A CA 1 ATOM 3863 C C . PHE A 1 566 ? -23.426 -1.370 -30.425 1.00 40.30 ? 566 PHE A C 1 ATOM 3864 O O . PHE A 1 566 ? -24.526 -1.197 -29.902 1.00 40.98 ? 566 PHE A O 1 ATOM 3865 C CB . PHE A 1 566 ? -22.308 0.868 -30.408 1.00 45.48 ? 566 PHE A CB 1 ATOM 3866 C CG . PHE A 1 566 ? -21.284 0.462 -29.385 1.00 49.50 ? 566 PHE A CG 1 ATOM 3867 C CD1 . PHE A 1 566 ? -19.937 0.422 -29.710 1.00 60.66 ? 566 PHE A CD1 1 ATOM 3868 C CD2 . PHE A 1 566 ? -21.668 0.118 -28.099 1.00 48.35 ? 566 PHE A CD2 1 ATOM 3869 C CE1 . PHE A 1 566 ? -18.993 0.047 -28.771 1.00 62.60 ? 566 PHE A CE1 1 ATOM 3870 C CE2 . PHE A 1 566 ? -20.729 -0.259 -27.156 1.00 48.07 ? 566 PHE A CE2 1 ATOM 3871 C CZ . PHE A 1 566 ? -19.392 -0.294 -27.492 1.00 53.96 ? 566 PHE A CZ 1 ATOM 3872 N N . THR A 1 567 ? -22.727 -2.490 -30.282 1.00 40.94 ? 567 THR A N 1 ATOM 3873 C CA . THR A 1 567 ? -23.211 -3.598 -29.467 1.00 43.96 ? 567 THR A CA 1 ATOM 3874 C C . THR A 1 567 ? -22.108 -4.130 -28.546 1.00 45.90 ? 567 THR A C 1 ATOM 3875 O O . THR A 1 567 ? -20.951 -4.224 -28.948 1.00 48.12 ? 567 THR A O 1 ATOM 3876 C CB . THR A 1 567 ? -23.822 -4.722 -30.345 1.00 49.58 ? 567 THR A CB 1 ATOM 3877 O OG1 . THR A 1 567 ? -23.994 -5.912 -29.567 1.00 43.17 ? 567 THR A OG1 1 ATOM 3878 C CG2 . THR A 1 567 ? -22.933 -5.022 -31.544 1.00 49.61 ? 567 THR A CG2 1 ATOM 3879 N N . ILE A 1 568 ? -22.473 -4.449 -27.305 1.00 48.09 ? 568 ILE A N 1 ATOM 3880 C CA . ILE A 1 568 ? -21.508 -4.897 -26.293 1.00 43.96 ? 568 ILE A CA 1 ATOM 3881 C C . ILE A 1 568 ? -20.797 -6.228 -26.612 1.00 47.80 ? 568 ILE A C 1 ATOM 3882 O O . ILE A 1 568 ? -19.579 -6.323 -26.455 1.00 54.60 ? 568 ILE A O 1 ATOM 3883 C CB . ILE A 1 568 ? -22.129 -4.913 -24.857 1.00 41.38 ? 568 ILE A CB 1 ATOM 3884 C CG1 . ILE A 1 568 ? -22.483 -3.493 -24.409 1.00 40.64 ? 568 ILE A CG1 1 ATOM 3885 C CG2 . ILE A 1 568 ? -21.184 -5.559 -23.856 1.00 42.10 ? 568 ILE A CG2 1 ATOM 3886 C CD1 . ILE A 1 568 ? -23.073 -3.416 -23.011 1.00 40.12 ? 568 ILE A CD1 1 ATOM 3887 N N . PRO A 1 569 ? -21.540 -7.258 -27.065 1.00 46.88 ? 569 PRO A N 1 ATOM 3888 C CA . PRO A 1 569 ? -20.845 -8.491 -27.461 1.00 48.54 ? 569 PRO A CA 1 ATOM 3889 C C . PRO A 1 569 ? -19.809 -8.298 -28.575 1.00 49.55 ? 569 PRO A C 1 ATOM 3890 O O . PRO A 1 569 ? -18.971 -9.178 -28.772 1.00 51.71 ? 569 PRO A O 1 ATOM 3891 C CB . PRO A 1 569 ? -21.986 -9.387 -27.947 1.00 49.64 ? 569 PRO A CB 1 ATOM 3892 C CG . PRO A 1 569 ? -23.154 -8.945 -27.149 1.00 49.57 ? 569 PRO A CG 1 ATOM 3893 C CD . PRO A 1 569 ? -23.001 -7.458 -27.008 1.00 48.20 ? 569 PRO A CD 1 ATOM 3894 N N . ASN A 1 570 ? -19.872 -7.179 -29.292 1.00 49.09 ? 570 ASN A N 1 ATOM 3895 C CA . ASN A 1 570 ? -18.844 -6.835 -30.273 1.00 54.27 ? 570 ASN A CA 1 ATOM 3896 C C . ASN A 1 570 ? -17.544 -6.366 -29.622 1.00 54.70 ? 570 ASN A C 1 ATOM 3897 O O . ASN A 1 570 ? -16.463 -6.575 -30.164 1.00 56.61 ? 570 ASN A O 1 ATOM 3898 C CB . ASN A 1 570 ? -19.352 -5.763 -31.243 1.00 57.47 ? 570 ASN A CB 1 ATOM 3899 C CG . ASN A 1 570 ? -19.889 -6.346 -32.537 1.00 70.68 ? 570 ASN A CG 1 ATOM 3900 O OD1 . ASN A 1 570 ? -20.037 -7.559 -32.672 1.00 70.33 ? 570 ASN A OD1 1 ATOM 3901 N ND2 . ASN A 1 570 ? -20.187 -5.478 -33.497 1.00 81.32 ? 570 ASN A ND2 1 ATOM 3902 N N . VAL A 1 571 ? -17.660 -5.699 -28.478 1.00 50.13 ? 571 VAL A N 1 ATOM 3903 C CA . VAL A 1 571 ? -16.495 -5.275 -27.698 1.00 44.20 ? 571 VAL A CA 1 ATOM 3904 C C . VAL A 1 571 ? -16.120 -6.241 -26.567 1.00 47.98 ? 571 VAL A C 1 ATOM 3905 O O . VAL A 1 571 ? -15.263 -5.925 -25.742 1.00 52.23 ? 571 VAL A O 1 ATOM 3906 C CB . VAL A 1 571 ? -16.639 -3.837 -27.136 1.00 42.34 ? 571 VAL A CB 1 ATOM 3907 C CG1 . VAL A 1 571 ? -16.105 -2.817 -28.126 1.00 45.57 ? 571 VAL A CG1 1 ATOM 3908 C CG2 . VAL A 1 571 ? -18.083 -3.538 -26.781 1.00 50.24 ? 571 VAL A CG2 1 ATOM 3909 N N . TYR A 1 572 ? -16.767 -7.404 -26.518 1.00 47.19 ? 572 TYR A N 1 ATOM 3910 C CA . TYR A 1 572 ? -16.627 -8.313 -25.378 1.00 47.23 ? 572 TYR A CA 1 ATOM 3911 C C . TYR A 1 572 ? -15.236 -8.945 -25.333 1.00 51.51 ? 572 TYR A C 1 ATOM 3912 O O . TYR A 1 572 ? -14.420 -8.746 -26.235 1.00 52.91 ? 572 TYR A O 1 ATOM 3913 C CB . TYR A 1 572 ? -17.695 -9.413 -25.454 1.00 48.17 ? 572 TYR A CB 1 ATOM 3914 C CG . TYR A 1 572 ? -18.042 -10.096 -24.142 1.00 42.62 ? 572 TYR A CG 1 ATOM 3915 C CD1 . TYR A 1 572 ? -18.763 -9.433 -23.158 1.00 41.22 ? 572 TYR A CD1 1 ATOM 3916 C CD2 . TYR A 1 572 ? -17.684 -11.418 -23.905 1.00 43.68 ? 572 TYR A CD2 1 ATOM 3917 C CE1 . TYR A 1 572 ? -19.096 -10.059 -21.967 1.00 43.89 ? 572 TYR A CE1 1 ATOM 3918 C CE2 . TYR A 1 572 ? -18.013 -12.050 -22.717 1.00 41.25 ? 572 TYR A CE2 1 ATOM 3919 C CZ . TYR A 1 572 ? -18.718 -11.367 -21.752 1.00 40.14 ? 572 TYR A CZ 1 ATOM 3920 O OH . TYR A 1 572 ? -19.047 -11.994 -20.571 1.00 34.19 ? 572 TYR A OH 1 ATOM 3921 N N . SER A 1 573 ? -14.995 -9.732 -24.288 1.00 54.87 ? 573 SER A N 1 ATOM 3922 C CA . SER A 1 573 ? -13.674 -10.261 -23.969 1.00 51.58 ? 573 SER A CA 1 ATOM 3923 C C . SER A 1 573 ? -13.796 -11.138 -22.734 1.00 50.42 ? 573 SER A C 1 ATOM 3924 O O . SER A 1 573 ? -14.653 -10.890 -21.888 1.00 53.14 ? 573 SER A O 1 ATOM 3925 C CB . SER A 1 573 ? -12.699 -9.119 -23.679 1.00 49.84 ? 573 SER A CB 1 ATOM 3926 O OG . SER A 1 573 ? -11.529 -9.596 -23.038 1.00 49.14 ? 573 SER A OG 1 ATOM 3927 N N . PRO A 1 574 ? -12.944 -12.170 -22.624 1.00 46.12 ? 574 PRO A N 1 ATOM 3928 C CA . PRO A 1 574 ? -12.970 -13.052 -21.453 1.00 52.10 ? 574 PRO A CA 1 ATOM 3929 C C . PRO A 1 574 ? -12.790 -12.287 -20.145 1.00 53.68 ? 574 PRO A C 1 ATOM 3930 O O . PRO A 1 574 ? -13.291 -12.715 -19.104 1.00 50.75 ? 574 PRO A O 1 ATOM 3931 C CB . PRO A 1 574 ? -11.774 -13.972 -21.689 1.00 52.75 ? 574 PRO A CB 1 ATOM 3932 C CG . PRO A 1 574 ? -11.618 -14.010 -23.163 1.00 48.86 ? 574 PRO A CG 1 ATOM 3933 C CD . PRO A 1 574 ? -11.988 -12.637 -23.645 1.00 47.26 ? 574 PRO A CD 1 ATOM 3934 N N . CYS A 1 575 ? -12.087 -11.160 -20.213 1.00 55.15 ? 575 CYS A N 1 ATOM 3935 C CA . CYS A 1 575 ? -11.855 -10.318 -19.044 1.00 55.63 ? 575 CYS A CA 1 ATOM 3936 C C . CYS A 1 575 ? -13.153 -9.734 -18.486 1.00 54.54 ? 575 CYS A C 1 ATOM 3937 O O . CYS A 1 575 ? -13.207 -9.328 -17.326 1.00 55.06 ? 575 CYS A O 1 ATOM 3938 C CB . CYS A 1 575 ? -10.872 -9.195 -19.382 1.00 54.01 ? 575 CYS A CB 1 ATOM 3939 S SG . CYS A 1 575 ? -9.169 -9.736 -19.664 1.00 62.21 ? 575 CYS A SG 1 ATOM 3940 N N . MET A 1 576 ? -14.187 -9.689 -19.323 1.00 53.43 ? 576 MET A N 1 ATOM 3941 C CA . MET A 1 576 ? -15.510 -9.234 -18.905 1.00 51.32 ? 576 MET A CA 1 ATOM 3942 C C . MET A 1 576 ? -16.220 -10.341 -18.132 1.00 50.25 ? 576 MET A C 1 ATOM 3943 O O . MET A 1 576 ? -17.081 -10.075 -17.295 1.00 46.16 ? 576 MET A O 1 ATOM 3944 C CB . MET A 1 576 ? -16.359 -8.840 -20.119 1.00 49.08 ? 576 MET A CB 1 ATOM 3945 C CG . MET A 1 576 ? -15.760 -7.760 -21.008 1.00 50.10 ? 576 MET A CG 1 ATOM 3946 S SD . MET A 1 576 ? -16.530 -6.145 -20.778 1.00 51.24 ? 576 MET A SD 1 ATOM 3947 C CE . MET A 1 576 ? -18.180 -6.451 -21.399 1.00 44.58 ? 576 MET A CE 1 ATOM 3948 N N . GLY A 1 577 ? -15.857 -11.586 -18.428 1.00 50.22 ? 577 GLY A N 1 ATOM 3949 C CA . GLY A 1 577 ? -16.450 -12.738 -17.773 1.00 51.11 ? 577 GLY A CA 1 ATOM 3950 C C . GLY A 1 577 ? -15.516 -13.340 -16.743 1.00 50.97 ? 577 GLY A C 1 ATOM 3951 O O . GLY A 1 577 ? -15.724 -14.458 -16.279 1.00 51.86 ? 577 GLY A O 1 ATOM 3952 N N . SER A 1 578 ? -14.498 -12.574 -16.368 1.00 54.27 ? 578 SER A N 1 ATOM 3953 C CA . SER A 1 578 ? -13.409 -13.069 -15.534 1.00 57.34 ? 578 SER A CA 1 ATOM 3954 C C . SER A 1 578 ? -13.511 -12.563 -14.106 1.00 50.79 ? 578 SER A C 1 ATOM 3955 O O . SER A 1 578 ? -14.034 -11.474 -13.869 1.00 46.58 ? 578 SER A O 1 ATOM 3956 C CB . SER A 1 578 ? -12.068 -12.614 -16.111 1.00 61.54 ? 578 SER A CB 1 ATOM 3957 O OG . SER A 1 578 ? -11.906 -11.212 -15.966 1.00 59.39 ? 578 SER A OG 1 ATOM 3958 N N . LEU A 1 579 ? -13.011 -13.340 -13.149 1.00 53.20 ? 579 LEU A N 1 ATOM 3959 C CA . LEU A 1 579 ? -12.867 -12.782 -11.818 1.00 57.05 ? 579 LEU A CA 1 ATOM 3960 C C . LEU A 1 579 ? -11.412 -12.384 -11.667 1.00 52.84 ? 579 LEU A C 1 ATOM 3961 O O . LEU A 1 579 ? -10.564 -13.206 -11.321 1.00 49.34 ? 579 LEU A O 1 ATOM 3962 C CB . LEU A 1 579 ? -13.175 -13.848 -10.763 1.00 51.59 ? 579 LEU A CB 1 ATOM 3963 C CG . LEU A 1 579 ? -14.416 -14.732 -10.908 1.00 46.01 ? 579 LEU A CG 1 ATOM 3964 C CD1 . LEU A 1 579 ? -14.283 -15.982 -10.049 1.00 36.23 ? 579 LEU A CD1 1 ATOM 3965 C CD2 . LEU A 1 579 ? -15.665 -13.960 -10.533 1.00 46.78 ? 579 LEU A CD2 1 ATOM 3966 N N . ARG A 1 580 ? -11.139 -11.105 -11.908 1.00 55.30 ? 580 ARG A N 1 ATOM 3967 C CA . ARG A 1 580 ? -9.886 -10.467 -11.534 1.00 53.53 ? 580 ARG A CA 1 ATOM 3968 C C . ARG A 1 580 ? -10.210 -9.032 -11.138 1.00 57.97 ? 580 ARG A C 1 ATOM 3969 O O . ARG A 1 580 ? -10.749 -8.278 -11.947 1.00 58.30 ? 580 ARG A O 1 ATOM 3970 C CB . ARG A 1 580 ? -8.889 -10.498 -12.697 1.00 55.76 ? 580 ARG A CB 1 ATOM 3971 C CG . ARG A 1 580 ? -8.410 -11.894 -13.089 1.00 58.27 ? 580 ARG A CG 1 ATOM 3972 C CD . ARG A 1 580 ? -7.279 -11.859 -14.105 1.00 56.61 ? 580 ARG A CD 1 ATOM 3973 N NE . ARG A 1 580 ? -6.149 -11.062 -13.638 1.00 51.42 ? 580 ARG A NE 1 ATOM 3974 C CZ . ARG A 1 580 ? -5.020 -10.889 -14.316 1.00 50.84 ? 580 ARG A CZ 1 ATOM 3975 N NH1 . ARG A 1 580 ? -4.857 -11.465 -15.498 1.00 54.30 ? 580 ARG A NH1 1 ATOM 3976 N NH2 . ARG A 1 580 ? -4.051 -10.141 -13.809 1.00 59.79 ? 580 ARG A NH2 1 ATOM 3977 N N . THR A 1 581 ? -9.882 -8.644 -9.911 1.00 62.01 ? 581 THR A N 1 ATOM 3978 C CA . THR A 1 581 ? -10.111 -7.269 -9.478 1.00 62.51 ? 581 THR A CA 1 ATOM 3979 C C . THR A 1 581 ? -8.828 -6.448 -9.601 1.00 63.39 ? 581 THR A C 1 ATOM 3980 O O . THR A 1 581 ? -8.802 -5.258 -9.283 1.00 61.63 ? 581 THR A O 1 ATOM 3981 C CB . THR A 1 581 ? -10.647 -7.212 -8.035 1.00 62.43 ? 581 THR A CB 1 ATOM 3982 O OG1 . THR A 1 581 ? -9.603 -7.555 -7.117 1.00 61.02 ? 581 THR A OG1 1 ATOM 3983 C CG2 . THR A 1 581 ? -11.805 -8.185 -7.864 1.00 60.49 ? 581 THR A CG2 1 ATOM 3984 N N . ASP A 1 582 ? -7.771 -7.100 -10.077 1.00 59.77 ? 582 ASP A N 1 ATOM 3985 C CA . ASP A 1 582 ? -6.425 -6.534 -10.048 1.00 55.94 ? 582 ASP A CA 1 ATOM 3986 C C . ASP A 1 582 ? -5.956 -5.839 -11.329 1.00 52.05 ? 582 ASP A C 1 ATOM 3987 O O . ASP A 1 582 ? -4.859 -5.288 -11.361 1.00 57.02 ? 582 ASP A O 1 ATOM 3988 C CB . ASP A 1 582 ? -5.421 -7.622 -9.660 1.00 60.67 ? 582 ASP A CB 1 ATOM 3989 C CG . ASP A 1 582 ? -5.547 -8.866 -10.521 1.00 55.81 ? 582 ASP A CG 1 ATOM 3990 O OD1 . ASP A 1 582 ? -6.345 -9.760 -10.170 1.00 49.53 ? 582 ASP A OD1 1 ATOM 3991 O OD2 . ASP A 1 582 ? -4.845 -8.949 -11.550 1.00 58.55 ? 582 ASP A OD2 1 ATOM 3992 N N . LEU A 1 583 ? -6.774 -5.850 -12.377 1.00 51.74 ? 583 LEU A N 1 ATOM 3993 C CA . LEU A 1 583 ? -6.367 -5.239 -13.644 1.00 56.24 ? 583 LEU A CA 1 ATOM 3994 C C . LEU A 1 583 ? -6.331 -3.714 -13.570 1.00 53.97 ? 583 LEU A C 1 ATOM 3995 O O . LEU A 1 583 ? -5.840 -3.048 -14.483 1.00 48.75 ? 583 LEU A O 1 ATOM 3996 C CB . LEU A 1 583 ? -7.270 -5.689 -14.794 1.00 59.85 ? 583 LEU A CB 1 ATOM 3997 C CG . LEU A 1 583 ? -6.866 -6.968 -15.529 1.00 50.92 ? 583 LEU A CG 1 ATOM 3998 C CD1 . LEU A 1 583 ? -5.374 -6.980 -15.790 1.00 51.07 ? 583 LEU A CD1 1 ATOM 3999 C CD2 . LEU A 1 583 ? -7.276 -8.198 -14.760 1.00 51.92 ? 583 LEU A CD2 1 ATOM 4000 N N . THR A 1 584 ? -6.855 -3.172 -12.477 1.00 53.71 ? 584 THR A N 1 ATOM 4001 C CA . THR A 1 584 ? -6.868 -1.733 -12.261 1.00 52.23 ? 584 THR A CA 1 ATOM 4002 C C . THR A 1 584 ? -5.613 -1.271 -11.530 1.00 64.98 ? 584 THR A C 1 ATOM 4003 O O . THR A 1 584 ? -5.467 -0.086 -11.230 1.00 68.26 ? 584 THR A O 1 ATOM 4004 C CB . THR A 1 584 ? -8.093 -1.302 -11.445 1.00 50.80 ? 584 THR A CB 1 ATOM 4005 O OG1 . THR A 1 584 ? -8.257 -2.186 -10.330 1.00 51.24 ? 584 THR A OG1 1 ATOM 4006 C CG2 . THR A 1 584 ? -9.344 -1.343 -12.301 1.00 62.78 ? 584 THR A CG2 1 ATOM 4007 N N . GLU A 1 585 ? -4.715 -2.210 -11.238 1.00 67.46 ? 585 GLU A N 1 ATOM 4008 C CA . GLU A 1 585 ? -3.452 -1.890 -10.574 1.00 67.77 ? 585 GLU A CA 1 ATOM 4009 C C . GLU A 1 585 ? -2.514 -1.103 -11.490 1.00 69.63 ? 585 GLU A C 1 ATOM 4010 O O . GLU A 1 585 ? -2.518 -1.293 -12.706 1.00 68.17 ? 585 GLU A O 1 ATOM 4011 C CB . GLU A 1 585 ? -2.768 -3.164 -10.066 1.00 70.54 ? 585 GLU A CB 1 ATOM 4012 C CG . GLU A 1 585 ? -3.472 -3.813 -8.879 1.00 78.98 ? 585 GLU A CG 1 ATOM 4013 C CD . GLU A 1 585 ? -2.801 -5.098 -8.423 1.00 87.25 ? 585 GLU A CD 1 ATOM 4014 O OE1 . GLU A 1 585 ? -1.911 -5.601 -9.142 1.00 79.50 ? 585 GLU A OE1 1 ATOM 4015 O OE2 . GLU A 1 585 ? -3.165 -5.604 -7.341 1.00 86.00 ? 585 GLU A OE2 1 ATOM 4016 N N . GLU A 1 586 ? -1.706 -0.230 -10.891 1.00 69.77 ? 586 GLU A N 1 ATOM 4017 C CA . GLU A 1 586 ? -0.844 0.695 -11.630 1.00 74.24 ? 586 GLU A CA 1 ATOM 4018 C C . GLU A 1 586 ? 0.053 0.015 -12.670 1.00 76.12 ? 586 GLU A C 1 ATOM 4019 O O . GLU A 1 586 ? 0.323 0.579 -13.733 1.00 69.63 ? 586 GLU A O 1 ATOM 4020 C CB . GLU A 1 586 ? -0.000 1.521 -10.652 1.00 75.72 ? 586 GLU A CB 1 ATOM 4021 C CG . GLU A 1 586 ? 0.956 2.501 -11.314 1.00 88.45 ? 586 GLU A CG 1 ATOM 4022 C CD . GLU A 1 586 ? 1.795 3.268 -10.310 1.00 96.42 ? 586 GLU A CD 1 ATOM 4023 O OE1 . GLU A 1 586 ? 1.353 3.422 -9.152 1.00 106.06 ? 586 GLU A OE1 1 ATOM 4024 O OE2 . GLU A 1 586 ? 2.901 3.715 -10.679 1.00 97.28 ? 586 GLU A OE2 1 ATOM 4025 N N . ILE A 1 587 ? 0.505 -1.196 -12.353 1.00 79.59 ? 587 ILE A N 1 ATOM 4026 C CA . ILE A 1 587 ? 1.339 -1.983 -13.258 1.00 73.90 ? 587 ILE A CA 1 ATOM 4027 C C . ILE A 1 587 ? 0.664 -2.171 -14.616 1.00 72.45 ? 587 ILE A C 1 ATOM 4028 O O . ILE A 1 587 ? 1.163 -1.704 -15.640 1.00 72.63 ? 587 ILE A O 1 ATOM 4029 C CB . ILE A 1 587 ? 1.673 -3.374 -12.666 1.00 69.85 ? 587 ILE A CB 1 ATOM 4030 C CG1 . ILE A 1 587 ? 2.329 -3.244 -11.286 1.00 68.05 ? 587 ILE A CG1 1 ATOM 4031 C CG2 . ILE A 1 587 ? 2.554 -4.169 -13.624 1.00 55.64 ? 587 ILE A CG2 1 ATOM 4032 C CD1 . ILE A 1 587 ? 1.365 -3.400 -10.118 1.00 59.95 ? 587 ILE A CD1 1 ATOM 4033 N N . HIS A 1 588 ? -0.474 -2.859 -14.608 1.00 72.52 ? 588 HIS A N 1 ATOM 4034 C CA . HIS A 1 588 ? -1.203 -3.186 -15.830 1.00 68.06 ? 588 HIS A CA 1 ATOM 4035 C C . HIS A 1 588 ? -1.724 -1.954 -16.575 1.00 68.11 ? 588 HIS A C 1 ATOM 4036 O O . HIS A 1 588 ? -1.722 -1.923 -17.806 1.00 70.55 ? 588 HIS A O 1 ATOM 4037 C CB . HIS A 1 588 ? -2.363 -4.139 -15.522 1.00 57.22 ? 588 HIS A CB 1 ATOM 4038 C CG . HIS A 1 588 ? -1.961 -5.358 -14.751 1.00 57.13 ? 588 HIS A CG 1 ATOM 4039 N ND1 . HIS A 1 588 ? -1.963 -5.402 -13.373 1.00 57.38 ? 588 HIS A ND1 1 ATOM 4040 C CD2 . HIS A 1 588 ? -1.552 -6.581 -15.164 1.00 57.06 ? 588 HIS A CD2 1 ATOM 4041 C CE1 . HIS A 1 588 ? -1.572 -6.597 -12.971 1.00 59.06 ? 588 HIS A CE1 1 ATOM 4042 N NE2 . HIS A 1 588 ? -1.316 -7.332 -14.039 1.00 57.95 ? 588 HIS A NE2 1 ATOM 4043 N N . VAL A 1 589 ? -2.179 -0.951 -15.828 1.00 64.03 ? 589 VAL A N 1 ATOM 4044 C CA . VAL A 1 589 ? -2.691 0.283 -16.422 1.00 65.70 ? 589 VAL A CA 1 ATOM 4045 C C . VAL A 1 589 ? -1.628 0.987 -17.262 1.00 73.64 ? 589 VAL A C 1 ATOM 4046 O O . VAL A 1 589 ? -1.880 1.369 -18.404 1.00 71.23 ? 589 VAL A O 1 ATOM 4047 C CB . VAL A 1 589 ? -3.212 1.259 -15.346 1.00 64.22 ? 589 VAL A CB 1 ATOM 4048 C CG1 . VAL A 1 589 ? -3.679 2.560 -15.982 1.00 60.44 ? 589 VAL A CG1 1 ATOM 4049 C CG2 . VAL A 1 589 ? -4.339 0.620 -14.552 1.00 67.50 ? 589 VAL A CG2 1 ATOM 4050 N N . MET A 1 590 ? -0.435 1.146 -16.696 1.00 75.40 ? 590 MET A N 1 ATOM 4051 C CA . MET A 1 590 ? 0.650 1.821 -17.399 1.00 78.54 ? 590 MET A CA 1 ATOM 4052 C C . MET A 1 590 ? 1.177 0.970 -18.557 1.00 78.66 ? 590 MET A C 1 ATOM 4053 O O . MET A 1 590 ? 1.870 1.472 -19.443 1.00 76.36 ? 590 MET A O 1 ATOM 4054 C CB . MET A 1 590 ? 1.778 2.191 -16.430 1.00 82.47 ? 590 MET A CB 1 ATOM 4055 C CG . MET A 1 590 ? 2.617 3.381 -16.880 1.00 99.00 ? 590 MET A CG 1 ATOM 4056 S SD . MET A 1 590 ? 1.632 4.881 -17.082 1.00 89.59 ? 590 MET A SD 1 ATOM 4057 C CE . MET A 1 590 ? 2.843 6.007 -17.773 1.00 89.87 ? 590 MET A CE 1 ATOM 4058 N N . ASN A 1 591 ? 0.845 -0.319 -18.541 1.00 77.54 ? 591 ASN A N 1 ATOM 4059 C CA . ASN A 1 591 ? 1.145 -1.204 -19.662 1.00 78.44 ? 591 ASN A CA 1 ATOM 4060 C C . ASN A 1 591 ? 0.164 -0.984 -20.807 1.00 79.54 ? 591 ASN A C 1 ATOM 4061 O O . ASN A 1 591 ? 0.485 -1.239 -21.966 1.00 83.02 ? 591 ASN A O 1 ATOM 4062 C CB . ASN A 1 591 ? 1.128 -2.673 -19.229 1.00 75.77 ? 591 ASN A CB 1 ATOM 4063 C CG . ASN A 1 591 ? 2.491 -3.167 -18.777 1.00 82.17 ? 591 ASN A CG 1 ATOM 4064 O OD1 . ASN A 1 591 ? 3.516 -2.547 -19.062 1.00 85.40 ? 591 ASN A OD1 1 ATOM 4065 N ND2 . ASN A 1 591 ? 2.508 -4.297 -18.079 1.00 84.08 ? 591 ASN A ND2 1 ATOM 4066 N N . LEU A 1 592 ? -1.035 -0.515 -20.474 1.00 74.04 ? 592 LEU A N 1 ATOM 4067 C CA . LEU A 1 592 ? -2.035 -0.190 -21.485 1.00 80.72 ? 592 LEU A CA 1 ATOM 4068 C C . LEU A 1 592 ? -1.605 1.051 -22.259 1.00 81.77 ? 592 LEU A C 1 ATOM 4069 O O . LEU A 1 592 ? -1.638 1.064 -23.489 1.00 85.46 ? 592 LEU A O 1 ATOM 4070 C CB . LEU A 1 592 ? -3.410 0.034 -20.843 1.00 85.64 ? 592 LEU A CB 1 ATOM 4071 C CG . LEU A 1 592 ? -4.608 0.174 -21.788 1.00 73.84 ? 592 LEU A CG 1 ATOM 4072 C CD1 . LEU A 1 592 ? -4.813 -1.113 -22.558 1.00 76.13 ? 592 LEU A CD1 1 ATOM 4073 C CD2 . LEU A 1 592 ? -5.877 0.545 -21.036 1.00 55.69 ? 592 LEU A CD2 1 ATOM 4074 N N . LEU A 1 593 ? -1.195 2.085 -21.529 1.00 74.91 ? 593 LEU A N 1 ATOM 4075 C CA . LEU A 1 593 ? -0.762 3.344 -22.131 1.00 80.09 ? 593 LEU A CA 1 ATOM 4076 C C . LEU A 1 593 ? 0.406 3.162 -23.101 1.00 89.25 ? 593 LEU A C 1 ATOM 4077 O O . LEU A 1 593 ? 0.482 3.842 -24.123 1.00 87.46 ? 593 LEU A O 1 ATOM 4078 C CB . LEU A 1 593 ? -0.389 4.363 -21.049 1.00 76.88 ? 593 LEU A CB 1 ATOM 4079 C CG . LEU A 1 593 ? -1.526 4.917 -20.190 1.00 72.56 ? 593 LEU A CG 1 ATOM 4080 C CD1 . LEU A 1 593 ? -1.035 6.058 -19.313 1.00 79.47 ? 593 LEU A CD1 1 ATOM 4081 C CD2 . LEU A 1 593 ? -2.667 5.380 -21.068 1.00 77.78 ? 593 LEU A CD2 1 ATOM 4082 N N . SER A 1 594 ? 1.313 2.245 -22.775 1.00 92.62 ? 594 SER A N 1 ATOM 4083 C CA . SER A 1 594 ? 2.461 1.969 -23.631 1.00 89.96 ? 594 SER A CA 1 ATOM 4084 C C . SER A 1 594 ? 2.103 0.965 -24.719 1.00 90.91 ? 594 SER A C 1 ATOM 4085 O O . SER A 1 594 ? 2.878 0.743 -25.655 1.00 95.11 ? 594 SER A O 1 ATOM 4086 C CB . SER A 1 594 ? 3.651 1.464 -22.809 1.00 90.09 ? 594 SER A CB 1 ATOM 4087 O OG . SER A 1 594 ? 3.379 0.196 -22.235 1.00 95.00 ? 594 SER A OG 1 ATOM 4088 N N . ALA A 1 595 ? 0.937 0.344 -24.585 1.00 91.75 ? 595 ALA A N 1 ATOM 4089 C CA . ALA A 1 595 ? 0.421 -0.534 -25.626 1.00 94.99 ? 595 ALA A CA 1 ATOM 4090 C C . ALA A 1 595 ? -0.497 0.233 -26.577 1.00 94.82 ? 595 ALA A C 1 ATOM 4091 O O . ALA A 1 595 ? -0.902 -0.290 -27.616 1.00 96.53 ? 595 ALA A O 1 ATOM 4092 C CB . ALA A 1 595 ? -0.331 -1.709 -25.005 1.00 94.01 ? 595 ALA A CB 1 ATOM 4093 N N . ILE A 1 596 ? -0.803 1.480 -26.227 1.00 93.74 ? 596 ILE A N 1 ATOM 4094 C CA . ILE A 1 596 ? -1.717 2.312 -27.017 1.00 99.63 ? 596 ILE A CA 1 ATOM 4095 C C . ILE A 1 596 ? -1.279 2.621 -28.465 1.00 100.32 ? 596 ILE A C 1 ATOM 4096 O O . ILE A 1 596 ? -2.073 2.451 -29.391 1.00 105.21 ? 596 ILE A O 1 ATOM 4097 C CB . ILE A 1 596 ? -2.117 3.617 -26.261 1.00 96.04 ? 596 ILE A CB 1 ATOM 4098 C CG1 . ILE A 1 596 ? -3.098 3.297 -25.132 1.00 90.66 ? 596 ILE A CG1 1 ATOM 4099 C CG2 . ILE A 1 596 ? -2.753 4.618 -27.207 1.00 102.10 ? 596 ILE A CG2 1 ATOM 4100 C CD1 . ILE A 1 596 ? -3.712 4.521 -24.479 1.00 96.12 ? 596 ILE A CD1 1 ATOM 4101 N N . PRO A 1 597 ? -0.024 3.066 -28.674 1.00 90.24 ? 597 PRO A N 1 ATOM 4102 C CA . PRO A 1 597 ? 0.380 3.392 -30.050 1.00 98.91 ? 597 PRO A CA 1 ATOM 4103 C C . PRO A 1 597 ? 0.359 2.202 -31.015 1.00 102.74 ? 597 PRO A C 1 ATOM 4104 O O . PRO A 1 597 ? 0.408 2.411 -32.228 1.00 105.28 ? 597 PRO A O 1 ATOM 4105 C CB . PRO A 1 597 ? 1.810 3.923 -29.883 1.00 107.33 ? 597 PRO A CB 1 ATOM 4106 C CG . PRO A 1 597 ? 2.275 3.377 -28.581 1.00 104.87 ? 597 PRO A CG 1 ATOM 4107 C CD . PRO A 1 597 ? 1.058 3.351 -27.714 1.00 95.53 ? 597 PRO A CD 1 ATOM 4108 N N . THR A 1 598 ? 0.285 0.982 -30.485 1.00 95.37 ? 598 THR A N 1 ATOM 4109 C CA . THR A 1 598 ? 0.255 -0.230 -31.307 1.00 99.57 ? 598 THR A CA 1 ATOM 4110 C C . THR A 1 598 ? -0.931 -0.258 -32.276 1.00 106.53 ? 598 THR A C 1 ATOM 4111 O O . THR A 1 598 ? -0.939 -1.023 -33.243 1.00 103.43 ? 598 THR A O 1 ATOM 4112 C CB . THR A 1 598 ? 0.232 -1.502 -30.438 1.00 91.54 ? 598 THR A CB 1 ATOM 4113 O OG1 . THR A 1 598 ? -0.948 -1.513 -29.626 1.00 93.82 ? 598 THR A OG1 1 ATOM 4114 C CG2 . THR A 1 598 ? 1.458 -1.553 -29.537 1.00 91.17 ? 598 THR A CG2 1 ATOM 4115 N N . ARG A 1 599 ? -1.926 0.582 -32.006 1.00 108.24 ? 599 ARG A N 1 ATOM 4116 C CA . ARG A 1 599 ? -3.066 0.774 -32.894 1.00 111.20 ? 599 ARG A CA 1 ATOM 4117 C C . ARG A 1 599 ? -3.058 2.238 -33.319 1.00 116.45 ? 599 ARG A C 1 ATOM 4118 O O . ARG A 1 599 ? -3.661 3.083 -32.658 1.00 115.13 ? 599 ARG A O 1 ATOM 4119 C CB . ARG A 1 599 ? -4.373 0.440 -32.173 1.00 102.51 ? 599 ARG A CB 1 ATOM 4120 C CG . ARG A 1 599 ? -4.456 -0.986 -31.646 1.00 90.30 ? 599 ARG A CG 1 ATOM 4121 C CD . ARG A 1 599 ? -5.644 -1.161 -30.712 1.00 78.97 ? 599 ARG A CD 1 ATOM 4122 N NE . ARG A 1 599 ? -5.857 -2.560 -30.358 1.00 74.30 ? 599 ARG A NE 1 ATOM 4123 C CZ . ARG A 1 599 ? -6.669 -3.380 -31.018 1.00 74.75 ? 599 ARG A CZ 1 ATOM 4124 N NH1 . ARG A 1 599 ? -7.348 -2.939 -32.068 1.00 72.35 ? 599 ARG A NH1 1 ATOM 4125 N NH2 . ARG A 1 599 ? -6.804 -4.639 -30.628 1.00 72.09 ? 599 ARG A NH2 1 ATOM 4126 N N . PRO A 1 600 ? -2.366 2.537 -34.431 1.00 119.80 ? 600 PRO A N 1 ATOM 4127 C CA . PRO A 1 600 ? -1.963 3.890 -34.841 1.00 122.78 ? 600 PRO A CA 1 ATOM 4128 C C . PRO A 1 600 ? -3.098 4.910 -34.871 1.00 117.80 ? 600 PRO A C 1 ATOM 4129 O O . PRO A 1 600 ? -2.928 6.025 -34.374 1.00 120.13 ? 600 PRO A O 1 ATOM 4130 C CB . PRO A 1 600 ? -1.405 3.677 -36.255 1.00 125.48 ? 600 PRO A CB 1 ATOM 4131 C CG . PRO A 1 600 ? -2.006 2.390 -36.718 1.00 118.12 ? 600 PRO A CG 1 ATOM 4132 C CD . PRO A 1 600 ? -2.093 1.546 -35.486 1.00 115.90 ? 600 PRO A CD 1 ATOM 4133 N N . GLY A 1 601 ? -4.237 4.534 -35.441 1.00 110.69 ? 601 GLY A N 1 ATOM 4134 C CA . GLY A 1 601 ? -5.372 5.433 -35.515 1.00 116.80 ? 601 GLY A CA 1 ATOM 4135 C C . GLY A 1 601 ? -5.911 5.796 -34.145 1.00 110.39 ? 601 GLY A C 1 ATOM 4136 O O . GLY A 1 601 ? -6.323 6.932 -33.913 1.00 112.62 ? 601 GLY A O 1 ATOM 4137 N N . LEU A 1 602 ? -5.902 4.826 -33.234 1.00 104.20 ? 602 LEU A N 1 ATOM 4138 C CA . LEU A 1 602 ? -6.421 5.027 -31.884 1.00 106.45 ? 602 LEU A CA 1 ATOM 4139 C C . LEU A 1 602 ? -5.654 6.097 -31.105 1.00 112.50 ? 602 LEU A C 1 ATOM 4140 O O . LEU A 1 602 ? -6.260 6.968 -30.481 1.00 111.66 ? 602 LEU A O 1 ATOM 4141 C CB . LEU A 1 602 ? -6.420 3.709 -31.103 1.00 100.79 ? 602 LEU A CB 1 ATOM 4142 C CG . LEU A 1 602 ? -6.778 3.807 -29.617 1.00 100.01 ? 602 LEU A CG 1 ATOM 4143 C CD1 . LEU A 1 602 ? -8.201 4.309 -29.437 1.00 93.95 ? 602 LEU A CD1 1 ATOM 4144 C CD2 . LEU A 1 602 ? -6.582 2.471 -28.911 1.00 96.80 ? 602 LEU A CD2 1 ATOM 4145 N N . ASN A 1 603 ? -4.326 6.027 -31.142 1.00 111.54 ? 603 ASN A N 1 ATOM 4146 C CA . ASN A 1 603 ? -3.489 6.961 -30.391 1.00 112.30 ? 603 ASN A CA 1 ATOM 4147 C C . ASN A 1 603 ? -3.626 8.398 -30.885 1.00 110.80 ? 603 ASN A C 1 ATOM 4148 O O . ASN A 1 603 ? -3.448 9.345 -30.121 1.00 113.03 ? 603 ASN A O 1 ATOM 4149 C CB . ASN A 1 603 ? -2.019 6.525 -30.418 1.00 111.96 ? 603 ASN A CB 1 ATOM 4150 C CG . ASN A 1 603 ? -1.136 7.372 -29.511 1.00 109.02 ? 603 ASN A CG 1 ATOM 4151 O OD1 . ASN A 1 603 ? -0.963 7.068 -28.330 1.00 97.82 ? 603 ASN A OD1 1 ATOM 4152 N ND2 . ASN A 1 603 ? -0.566 8.437 -30.066 1.00 115.68 ? 603 ASN A ND2 1 ATOM 4153 N N . GLU A 1 604 ? -3.944 8.557 -32.165 1.00 107.45 ? 604 GLU A N 1 ATOM 4154 C CA . GLU A 1 604 ? -4.122 9.885 -32.738 1.00 114.69 ? 604 GLU A CA 1 ATOM 4155 C C . GLU A 1 604 ? -5.385 10.551 -32.194 1.00 121.23 ? 604 GLU A C 1 ATOM 4156 O O . GLU A 1 604 ? -5.333 11.666 -31.675 1.00 119.66 ? 604 GLU A O 1 ATOM 4157 C CB . GLU A 1 604 ? -4.169 9.809 -34.267 1.00 124.97 ? 604 GLU A CB 1 ATOM 4158 C CG . GLU A 1 604 ? -4.237 11.161 -34.963 1.00 135.82 ? 604 GLU A CG 1 ATOM 4159 C CD . GLU A 1 604 ? -4.026 11.060 -36.464 1.00 136.97 ? 604 GLU A CD 1 ATOM 4160 O OE1 . GLU A 1 604 ? -4.032 9.930 -36.996 1.00 130.37 ? 604 GLU A OE1 1 ATOM 4161 O OE2 . GLU A 1 604 ? -3.849 12.114 -37.112 1.00 132.67 ? 604 GLU A OE2 1 ATOM 4162 N N . VAL A 1 605 ? -6.510 9.849 -32.297 1.00 124.21 ? 605 VAL A N 1 ATOM 4163 C CA . VAL A 1 605 ? -7.807 10.380 -31.883 1.00 118.90 ? 605 VAL A CA 1 ATOM 4164 C C . VAL A 1 605 ? -7.888 10.647 -30.376 1.00 116.98 ? 605 VAL A C 1 ATOM 4165 O O . VAL A 1 605 ? -8.540 11.596 -29.941 1.00 116.42 ? 605 VAL A O 1 ATOM 4166 C CB . VAL A 1 605 ? -8.955 9.433 -32.303 1.00 110.21 ? 605 VAL A CB 1 ATOM 4167 C CG1 . VAL A 1 605 ? -10.305 10.096 -32.086 1.00 120.59 ? 605 VAL A CG1 1 ATOM 4168 C CG2 . VAL A 1 605 ? -8.798 9.024 -33.758 1.00 100.04 ? 605 VAL A CG2 1 ATOM 4169 N N . LEU A 1 606 ? -7.221 9.811 -29.584 1.00 112.41 ? 606 LEU A N 1 ATOM 4170 C CA . LEU A 1 606 ? -7.244 9.951 -28.129 1.00 115.82 ? 606 LEU A CA 1 ATOM 4171 C C . LEU A 1 606 ? -6.580 11.244 -27.647 1.00 121.77 ? 606 LEU A C 1 ATOM 4172 O O . LEU A 1 606 ? -7.058 11.881 -26.706 1.00 120.71 ? 606 LEU A O 1 ATOM 4173 C CB . LEU A 1 606 ? -6.589 8.739 -27.457 1.00 114.79 ? 606 LEU A CB 1 ATOM 4174 C CG . LEU A 1 606 ? -7.520 7.740 -26.764 1.00 102.73 ? 606 LEU A CG 1 ATOM 4175 C CD1 . LEU A 1 606 ? -6.737 6.579 -26.161 1.00 93.55 ? 606 LEU A CD1 1 ATOM 4176 C CD2 . LEU A 1 606 ? -8.339 8.442 -25.697 1.00 100.98 ? 606 LEU A CD2 1 ATOM 4177 N N . HIS A 1 607 ? -5.483 11.627 -28.295 1.00 117.97 ? 607 HIS A N 1 ATOM 4178 C CA . HIS A 1 607 ? -4.724 12.811 -27.896 1.00 115.09 ? 607 HIS A CA 1 ATOM 4179 C C . HIS A 1 607 ? -5.364 14.122 -28.362 1.00 118.29 ? 607 HIS A C 1 ATOM 4180 O O . HIS A 1 607 ? -5.017 15.195 -27.868 1.00 118.78 ? 607 HIS A O 1 ATOM 4181 C CB . HIS A 1 607 ? -3.282 12.729 -28.413 1.00 115.60 ? 607 HIS A CB 1 ATOM 4182 C CG . HIS A 1 607 ? -2.403 11.803 -27.628 1.00 110.07 ? 607 HIS A CG 1 ATOM 4183 N ND1 . HIS A 1 607 ? -2.330 10.450 -27.880 1.00 107.65 ? 607 HIS A ND1 1 ATOM 4184 C CD2 . HIS A 1 607 ? -1.551 12.040 -26.602 1.00 101.94 ? 607 HIS A CD2 1 ATOM 4185 C CE1 . HIS A 1 607 ? -1.476 9.892 -27.041 1.00 98.49 ? 607 HIS A CE1 1 ATOM 4186 N NE2 . HIS A 1 607 ? -0.989 10.835 -26.254 1.00 101.46 ? 607 HIS A NE2 1 ATOM 4187 N N . THR A 1 608 ? -6.298 14.032 -29.306 1.00 123.07 ? 608 THR A N 1 ATOM 4188 C CA . THR A 1 608 ? -6.915 15.225 -29.889 1.00 126.18 ? 608 THR A CA 1 ATOM 4189 C C . THR A 1 608 ? -8.088 15.763 -29.070 1.00 119.82 ? 608 THR A C 1 ATOM 4190 O O . THR A 1 608 ? -8.620 16.834 -29.366 1.00 120.57 ? 608 THR A O 1 ATOM 4191 C CB . THR A 1 608 ? -7.391 14.975 -31.336 1.00 128.15 ? 608 THR A CB 1 ATOM 4192 O OG1 . THR A 1 608 ? -8.320 13.884 -31.359 1.00 116.55 ? 608 THR A OG1 1 ATOM 4193 C CG2 . THR A 1 608 ? -6.209 14.654 -32.238 1.00 135.40 ? 608 THR A CG2 1 ATOM 4194 N N . GLN A 1 609 ? -8.489 15.017 -28.046 1.00 117.56 ? 609 GLN A N 1 ATOM 4195 C CA . GLN A 1 609 ? -9.572 15.439 -27.163 1.00 116.64 ? 609 GLN A CA 1 ATOM 4196 C C . GLN A 1 609 ? -9.126 15.451 -25.703 1.00 111.54 ? 609 GLN A C 1 ATOM 4197 O O . GLN A 1 609 ? -9.116 16.497 -25.052 1.00 104.80 ? 609 GLN A O 1 ATOM 4198 C CB . GLN A 1 609 ? -10.812 14.556 -27.352 1.00 117.37 ? 609 GLN A CB 1 ATOM 4199 C CG . GLN A 1 609 ? -10.513 13.092 -27.649 1.00 115.90 ? 609 GLN A CG 1 ATOM 4200 C CD . GLN A 1 609 ? -11.770 12.276 -27.890 1.00 119.85 ? 609 GLN A CD 1 ATOM 4201 O OE1 . GLN A 1 609 ? -12.856 12.637 -27.437 1.00 115.29 ? 609 GLN A OE1 1 ATOM 4202 N NE2 . GLN A 1 609 ? -11.627 11.169 -28.612 1.00 118.36 ? 609 GLN A NE2 1 ATOM 4203 N N . LEU A 1 610 ? -8.762 14.278 -25.196 1.00 107.81 ? 610 LEU A N 1 ATOM 4204 C CA . LEU A 1 610 ? -8.361 14.130 -23.804 1.00 104.42 ? 610 LEU A CA 1 ATOM 4205 C C . LEU A 1 610 ? -6.905 14.530 -23.557 1.00 106.81 ? 610 LEU A C 1 ATOM 4206 O O . LEU A 1 610 ? -6.020 14.241 -24.364 1.00 104.98 ? 610 LEU A O 1 ATOM 4207 C CB . LEU A 1 610 ? -8.604 12.695 -23.329 1.00 99.40 ? 610 LEU A CB 1 ATOM 4208 C CG . LEU A 1 610 ? -10.013 12.344 -22.842 1.00 95.98 ? 610 LEU A CG 1 ATOM 4209 C CD1 . LEU A 1 610 ? -11.052 12.458 -23.947 1.00 106.59 ? 610 LEU A CD1 1 ATOM 4210 C CD2 . LEU A 1 610 ? -10.028 10.951 -22.250 1.00 90.62 ? 610 LEU A CD2 1 ATOM 4211 N N . ASP A 1 611 ? -6.677 15.204 -22.434 1.00 104.77 ? 611 ASP A N 1 ATOM 4212 C CA . ASP A 1 611 ? -5.338 15.563 -21.983 1.00 103.57 ? 611 ASP A CA 1 ATOM 4213 C C . ASP A 1 611 ? -4.561 14.294 -21.647 1.00 102.17 ? 611 ASP A C 1 ATOM 4214 O O . ASP A 1 611 ? -5.159 13.262 -21.346 1.00 101.51 ? 611 ASP A O 1 ATOM 4215 C CB . ASP A 1 611 ? -5.442 16.476 -20.754 1.00 107.09 ? 611 ASP A CB 1 ATOM 4216 C CG . ASP A 1 611 ? -4.106 16.709 -20.071 1.00 113.68 ? 611 ASP A CG 1 ATOM 4217 O OD1 . ASP A 1 611 ? -3.063 16.700 -20.760 1.00 113.86 ? 611 ASP A OD1 1 ATOM 4218 O OD2 . ASP A 1 611 ? -4.102 16.907 -18.837 1.00 109.70 ? 611 ASP A OD2 1 ATOM 4219 N N . GLU A 1 612 ? -3.233 14.370 -21.704 1.00 101.57 ? 612 GLU A N 1 ATOM 4220 C CA . GLU A 1 612 ? -2.376 13.233 -21.373 1.00 97.28 ? 612 GLU A CA 1 ATOM 4221 C C . GLU A 1 612 ? -2.652 12.710 -19.963 1.00 99.40 ? 612 GLU A C 1 ATOM 4222 O O . GLU A 1 612 ? -2.378 11.549 -19.657 1.00 97.73 ? 612 GLU A O 1 ATOM 4223 C CB . GLU A 1 612 ? -0.909 13.606 -21.530 1.00 94.03 ? 612 GLU A CB 1 ATOM 4224 N N . SER A 1 613 ? -3.189 13.579 -19.111 1.00 103.26 ? 613 SER A N 1 ATOM 4225 C CA . SER A 1 613 ? -3.634 13.190 -17.779 1.00 102.23 ? 613 SER A CA 1 ATOM 4226 C C . SER A 1 613 ? -4.984 12.481 -17.846 1.00 103.07 ? 613 SER A C 1 ATOM 4227 O O . SER A 1 613 ? -5.241 11.543 -17.091 1.00 95.70 ? 613 SER A O 1 ATOM 4228 C CB . SER A 1 613 ? -3.726 14.416 -16.868 1.00 98.16 ? 613 SER A CB 1 ATOM 4229 O OG . SER A 1 613 ? -4.494 14.140 -15.710 1.00 100.59 ? 613 SER A OG 1 ATOM 4230 N N . GLU A 1 614 ? -5.843 12.936 -18.755 1.00 105.93 ? 614 GLU A N 1 ATOM 4231 C CA . GLU A 1 614 ? -7.160 12.333 -18.941 1.00 102.35 ? 614 GLU A CA 1 ATOM 4232 C C . GLU A 1 614 ? -7.058 10.958 -19.598 1.00 94.94 ? 614 GLU A C 1 ATOM 4233 O O . GLU A 1 614 ? -7.885 10.082 -19.347 1.00 92.67 ? 614 GLU A O 1 ATOM 4234 C CB . GLU A 1 614 ? -8.066 13.242 -19.779 1.00 105.64 ? 614 GLU A CB 1 ATOM 4235 C CG . GLU A 1 614 ? -8.329 14.619 -19.183 1.00 110.92 ? 614 GLU A CG 1 ATOM 4236 C CD . GLU A 1 614 ? -9.325 15.426 -20.001 1.00 110.85 ? 614 GLU A CD 1 ATOM 4237 O OE1 . GLU A 1 614 ? -9.039 16.606 -20.296 1.00 114.45 ? 614 GLU A OE1 1 ATOM 4238 O OE2 . GLU A 1 614 ? -10.397 14.883 -20.344 1.00 104.13 ? 614 GLU A OE2 1 ATOM 4239 N N . ILE A 1 615 ? -6.045 10.778 -20.442 1.00 96.49 ? 615 ILE A N 1 ATOM 4240 C CA . ILE A 1 615 ? -5.827 9.502 -21.119 1.00 92.84 ? 615 ILE A CA 1 ATOM 4241 C C . ILE A 1 615 ? -5.447 8.409 -20.121 1.00 90.92 ? 615 ILE A C 1 ATOM 4242 O O . ILE A 1 615 ? -5.883 7.265 -20.250 1.00 86.25 ? 615 ILE A O 1 ATOM 4243 C CB . ILE A 1 615 ? -4.747 9.611 -22.219 1.00 91.25 ? 615 ILE A CB 1 ATOM 4244 C CG1 . ILE A 1 615 ? -5.093 10.732 -23.202 1.00 98.97 ? 615 ILE A CG1 1 ATOM 4245 C CG2 . ILE A 1 615 ? -4.611 8.296 -22.968 1.00 91.37 ? 615 ILE A CG2 1 ATOM 4246 C CD1 . ILE A 1 615 ? -4.009 11.016 -24.222 1.00 104.83 ? 615 ILE A CD1 1 ATOM 4247 N N . PHE A 1 616 ? -4.640 8.764 -19.124 1.00 96.77 ? 616 PHE A N 1 ATOM 4248 C CA . PHE A 1 616 ? -4.285 7.823 -18.064 1.00 94.13 ? 616 PHE A CA 1 ATOM 4249 C C . PHE A 1 616 ? -5.512 7.442 -17.244 1.00 93.41 ? 616 PHE A C 1 ATOM 4250 O O . PHE A 1 616 ? -5.647 6.298 -16.809 1.00 93.63 ? 616 PHE A O 1 ATOM 4251 C CB . PHE A 1 616 ? -3.201 8.398 -17.149 1.00 90.59 ? 616 PHE A CB 1 ATOM 4252 C CG . PHE A 1 616 ? -2.937 7.563 -15.924 1.00 93.03 ? 616 PHE A CG 1 ATOM 4253 C CD1 . PHE A 1 616 ? -2.222 6.380 -16.016 1.00 90.09 ? 616 PHE A CD1 1 ATOM 4254 C CD2 . PHE A 1 616 ? -3.406 7.960 -14.682 1.00 103.82 ? 616 PHE A CD2 1 ATOM 4255 C CE1 . PHE A 1 616 ? -1.980 5.608 -14.893 1.00 99.22 ? 616 PHE A CE1 1 ATOM 4256 C CE2 . PHE A 1 616 ? -3.167 7.193 -13.554 1.00 100.18 ? 616 PHE A CE2 1 ATOM 4257 C CZ . PHE A 1 616 ? -2.452 6.016 -13.660 1.00 98.80 ? 616 PHE A CZ 1 ATOM 4258 N N . ASP A 1 617 ? -6.402 8.408 -17.030 1.00 92.37 ? 617 ASP A N 1 ATOM 4259 C CA . ASP A 1 617 ? -7.655 8.151 -16.331 1.00 94.55 ? 617 ASP A CA 1 ATOM 4260 C C . ASP A 1 617 ? -8.598 7.331 -17.208 1.00 89.40 ? 617 ASP A C 1 ATOM 4261 O O . ASP A 1 617 ? -9.153 6.330 -16.763 1.00 87.61 ? 617 ASP A O 1 ATOM 4262 C CB . ASP A 1 617 ? -8.329 9.461 -15.904 1.00 101.68 ? 617 ASP A CB 1 ATOM 4263 C CG . ASP A 1 617 ? -8.257 9.698 -14.402 1.00 105.09 ? 617 ASP A CG 1 ATOM 4264 O OD1 . ASP A 1 617 ? -7.148 9.609 -13.833 1.00 118.21 ? 617 ASP A OD1 1 ATOM 4265 O OD2 . ASP A 1 617 ? -9.312 9.970 -13.790 1.00 89.44 ? 617 ASP A OD2 1 ATOM 4266 N N . ALA A 1 618 ? -8.767 7.756 -18.457 1.00 87.36 ? 618 ALA A N 1 ATOM 4267 C CA . ALA A 1 618 ? -9.633 7.051 -19.400 1.00 83.48 ? 618 ALA A CA 1 ATOM 4268 C C . ALA A 1 618 ? -9.197 5.603 -19.586 1.00 76.88 ? 618 ALA A C 1 ATOM 4269 O O . ALA A 1 618 ? -10.028 4.713 -19.759 1.00 78.08 ? 618 ALA A O 1 ATOM 4270 C CB . ALA A 1 618 ? -9.660 7.767 -20.733 1.00 87.66 ? 618 ALA A CB 1 ATOM 4271 N N . ALA A 1 619 ? -7.888 5.375 -19.553 1.00 70.86 ? 619 ALA A N 1 ATOM 4272 C CA . ALA A 1 619 ? -7.347 4.026 -19.652 1.00 69.07 ? 619 ALA A CA 1 ATOM 4273 C C . ALA A 1 619 ? -7.580 3.253 -18.356 1.00 65.80 ? 619 ALA A C 1 ATOM 4274 O O . ALA A 1 619 ? -7.652 2.025 -18.360 1.00 61.46 ? 619 ALA A O 1 ATOM 4275 C CB . ALA A 1 619 ? -5.873 4.066 -19.998 1.00 76.82 ? 619 ALA A CB 1 ATOM 4276 N N . PHE A 1 620 ? -7.694 3.979 -17.248 1.00 70.36 ? 620 PHE A N 1 ATOM 4277 C CA . PHE A 1 620 ? -8.038 3.368 -15.968 1.00 70.89 ? 620 PHE A CA 1 ATOM 4278 C C . PHE A 1 620 ? -9.528 3.046 -15.922 1.00 71.06 ? 620 PHE A C 1 ATOM 4279 O O . PHE A 1 620 ? -9.933 2.022 -15.373 1.00 69.17 ? 620 PHE A O 1 ATOM 4280 C CB . PHE A 1 620 ? -7.654 4.292 -14.807 1.00 71.07 ? 620 PHE A CB 1 ATOM 4281 C CG . PHE A 1 620 ? -8.069 3.780 -13.456 1.00 66.70 ? 620 PHE A CG 1 ATOM 4282 C CD1 . PHE A 1 620 ? -7.516 2.620 -12.937 1.00 64.47 ? 620 PHE A CD1 1 ATOM 4283 C CD2 . PHE A 1 620 ? -8.999 4.470 -12.695 1.00 64.64 ? 620 PHE A CD2 1 ATOM 4284 C CE1 . PHE A 1 620 ? -7.892 2.152 -11.690 1.00 59.28 ? 620 PHE A CE1 1 ATOM 4285 C CE2 . PHE A 1 620 ? -9.379 4.007 -11.448 1.00 68.17 ? 620 PHE A CE2 1 ATOM 4286 C CZ . PHE A 1 620 ? -8.825 2.847 -10.946 1.00 66.04 ? 620 PHE A CZ 1 ATOM 4287 N N . LYS A 1 621 ? -10.335 3.927 -16.505 1.00 72.62 ? 621 LYS A N 1 ATOM 4288 C CA . LYS A 1 621 ? -11.777 3.720 -16.595 1.00 64.43 ? 621 LYS A CA 1 ATOM 4289 C C . LYS A 1 621 ? -12.118 2.423 -17.333 1.00 63.68 ? 621 LYS A C 1 ATOM 4290 O O . LYS A 1 621 ? -12.933 1.631 -16.862 1.00 63.59 ? 621 LYS A O 1 ATOM 4291 C CB . LYS A 1 621 ? -12.452 4.912 -17.286 1.00 66.89 ? 621 LYS A CB 1 ATOM 4292 C CG . LYS A 1 621 ? -13.041 5.965 -16.345 1.00 71.47 ? 621 LYS A CG 1 ATOM 4293 C CD . LYS A 1 621 ? -12.077 7.111 -16.071 1.00 74.57 ? 621 LYS A CD 1 ATOM 4294 C CE . LYS A 1 621 ? -11.441 6.996 -14.692 1.00 86.80 ? 621 LYS A CE 1 ATOM 4295 N NZ . LYS A 1 621 ? -12.424 7.204 -13.593 1.00 99.65 ? 621 LYS A NZ 1 ATOM 4296 N N . THR A 1 622 ? -11.485 2.209 -18.485 1.00 64.85 ? 622 THR A N 1 ATOM 4297 C CA . THR A 1 622 ? -11.751 1.024 -19.301 1.00 61.04 ? 622 THR A CA 1 ATOM 4298 C C . THR A 1 622 ? -11.148 -0.252 -18.707 1.00 55.20 ? 622 THR A C 1 ATOM 4299 O O . THR A 1 622 ? -11.496 -1.358 -19.119 1.00 56.06 ? 622 THR A O 1 ATOM 4300 C CB . THR A 1 622 ? -11.295 1.217 -20.773 1.00 48.88 ? 622 THR A CB 1 ATOM 4301 O OG1 . THR A 1 622 ? -11.358 -0.032 -21.472 1.00 43.12 ? 622 THR A OG1 1 ATOM 4302 C CG2 . THR A 1 622 ? -9.879 1.738 -20.832 1.00 61.21 ? 622 THR A CG2 1 ATOM 4303 N N . MET A 1 623 ? -10.242 -0.097 -17.746 1.00 51.42 ? 623 MET A N 1 ATOM 4304 C CA . MET A 1 623 ? -9.722 -1.248 -17.014 1.00 54.23 ? 623 MET A CA 1 ATOM 4305 C C . MET A 1 623 ? -10.620 -1.609 -15.831 1.00 54.09 ? 623 MET A C 1 ATOM 4306 O O . MET A 1 623 ? -10.550 -2.718 -15.300 1.00 48.75 ? 623 MET A O 1 ATOM 4307 C CB . MET A 1 623 ? -8.284 -0.996 -16.548 1.00 57.62 ? 623 MET A CB 1 ATOM 4308 C CG . MET A 1 623 ? -7.229 -1.492 -17.523 1.00 55.00 ? 623 MET A CG 1 ATOM 4309 S SD . MET A 1 623 ? -7.286 -3.287 -17.703 1.00 48.84 ? 623 MET A SD 1 ATOM 4310 C CE . MET A 1 623 ? -6.256 -3.518 -19.150 1.00 60.50 ? 623 MET A CE 1 ATOM 4311 N N . MET A 1 624 ? -11.478 -0.671 -15.440 1.00 54.38 ? 624 MET A N 1 ATOM 4312 C CA . MET A 1 624 ? -12.414 -0.888 -14.341 1.00 57.72 ? 624 MET A CA 1 ATOM 4313 C C . MET A 1 624 ? -13.495 -1.893 -14.725 1.00 64.22 ? 624 MET A C 1 ATOM 4314 O O . MET A 1 624 ? -13.937 -2.687 -13.895 1.00 65.06 ? 624 MET A O 1 ATOM 4315 C CB . MET A 1 624 ? -13.061 0.436 -13.921 1.00 62.47 ? 624 MET A CB 1 ATOM 4316 C CG . MET A 1 624 ? -12.518 1.016 -12.630 1.00 65.13 ? 624 MET A CG 1 ATOM 4317 S SD . MET A 1 624 ? -12.788 -0.094 -11.237 1.00 78.38 ? 624 MET A SD 1 ATOM 4318 C CE . MET A 1 624 ? -14.574 -0.230 -11.263 1.00 83.86 ? 624 MET A CE 1 ATOM 4319 N N . ILE A 1 625 ? -13.905 -1.846 -15.991 1.00 63.49 ? 625 ILE A N 1 ATOM 4320 C CA . ILE A 1 625 ? -14.967 -2.697 -16.525 1.00 53.53 ? 625 ILE A CA 1 ATOM 4321 C C . ILE A 1 625 ? -14.740 -4.185 -16.269 1.00 56.59 ? 625 ILE A C 1 ATOM 4322 O O . ILE A 1 625 ? -15.619 -4.872 -15.750 1.00 63.51 ? 625 ILE A O 1 ATOM 4323 C CB . ILE A 1 625 ? -15.145 -2.482 -18.040 1.00 42.67 ? 625 ILE A CB 1 ATOM 4324 C CG1 . ILE A 1 625 ? -15.443 -1.015 -18.343 1.00 42.68 ? 625 ILE A CG1 1 ATOM 4325 C CG2 . ILE A 1 625 ? -16.256 -3.361 -18.577 1.00 48.79 ? 625 ILE A CG2 1 ATOM 4326 C CD1 . ILE A 1 625 ? -15.645 -0.726 -19.814 1.00 47.13 ? 625 ILE A CD1 1 ATOM 4327 N N . PHE A 1 626 ? -13.558 -4.672 -16.635 1.00 56.46 ? 626 PHE A N 1 ATOM 4328 C CA . PHE A 1 626 ? -13.224 -6.087 -16.506 1.00 57.40 ? 626 PHE A CA 1 ATOM 4329 C C . PHE A 1 626 ? -13.325 -6.576 -15.059 1.00 61.25 ? 626 PHE A C 1 ATOM 4330 O O . PHE A 1 626 ? -13.738 -7.707 -14.803 1.00 56.43 ? 626 PHE A O 1 ATOM 4331 C CB . PHE A 1 626 ? -11.821 -6.355 -17.060 1.00 57.36 ? 626 PHE A CB 1 ATOM 4332 C CG . PHE A 1 626 ? -11.657 -5.992 -18.514 1.00 54.68 ? 626 PHE A CG 1 ATOM 4333 C CD1 . PHE A 1 626 ? -12.747 -5.978 -19.373 1.00 56.20 ? 626 PHE A CD1 1 ATOM 4334 C CD2 . PHE A 1 626 ? -10.409 -5.670 -19.022 1.00 56.56 ? 626 PHE A CD2 1 ATOM 4335 C CE1 . PHE A 1 626 ? -12.592 -5.645 -20.709 1.00 56.47 ? 626 PHE A CE1 1 ATOM 4336 C CE2 . PHE A 1 626 ? -10.249 -5.338 -20.356 1.00 59.05 ? 626 PHE A CE2 1 ATOM 4337 C CZ . PHE A 1 626 ? -11.342 -5.325 -21.200 1.00 57.17 ? 626 PHE A CZ 1 ATOM 4338 N N . THR A 1 627 ? -12.943 -5.719 -14.119 1.00 64.98 ? 627 THR A N 1 ATOM 4339 C CA . THR A 1 627 ? -13.035 -6.047 -12.699 1.00 69.17 ? 627 THR A CA 1 ATOM 4340 C C . THR A 1 627 ? -14.452 -5.862 -12.169 1.00 65.54 ? 627 THR A C 1 ATOM 4341 O O . THR A 1 627 ? -14.890 -6.588 -11.278 1.00 69.71 ? 627 THR A O 1 ATOM 4342 C CB . THR A 1 627 ? -12.074 -5.193 -11.852 1.00 71.30 ? 627 THR A CB 1 ATOM 4343 O OG1 . THR A 1 627 ? -12.811 -4.169 -11.172 1.00 70.02 ? 627 THR A OG1 1 ATOM 4344 C CG2 . THR A 1 627 ? -11.008 -4.558 -12.732 1.00 61.03 ? 627 THR A CG2 1 ATOM 4345 N N . THR A 1 628 ? -15.164 -4.882 -12.717 1.00 60.81 ? 628 THR A N 1 ATOM 4346 C CA . THR A 1 628 ? -16.481 -4.525 -12.201 1.00 63.99 ? 628 THR A CA 1 ATOM 4347 C C . THR A 1 628 ? -17.635 -5.240 -12.903 1.00 61.07 ? 628 THR A C 1 ATOM 4348 O O . THR A 1 628 ? -18.798 -5.012 -12.572 1.00 65.43 ? 628 THR A O 1 ATOM 4349 C CB . THR A 1 628 ? -16.725 -2.996 -12.246 1.00 68.04 ? 628 THR A CB 1 ATOM 4350 O OG1 . THR A 1 628 ? -17.796 -2.646 -11.358 1.00 76.15 ? 628 THR A OG1 1 ATOM 4351 C CG2 . THR A 1 628 ? -17.079 -2.546 -13.651 1.00 65.94 ? 628 THR A CG2 1 ATOM 4352 N N . TRP A 1 629 ? -17.330 -6.109 -13.860 1.00 57.96 ? 629 TRP A N 1 ATOM 4353 C CA . TRP A 1 629 ? -18.402 -6.727 -14.634 1.00 54.57 ? 629 TRP A CA 1 ATOM 4354 C C . TRP A 1 629 ? -18.946 -7.985 -13.967 1.00 53.38 ? 629 TRP A C 1 ATOM 4355 O O . TRP A 1 629 ? -20.018 -7.960 -13.365 1.00 64.29 ? 629 TRP A O 1 ATOM 4356 C CB . TRP A 1 629 ? -17.911 -7.067 -16.043 1.00 54.31 ? 629 TRP A CB 1 ATOM 4357 C CG . TRP A 1 629 ? -19.011 -7.218 -17.048 1.00 52.85 ? 629 TRP A CG 1 ATOM 4358 C CD1 . TRP A 1 629 ? -19.526 -8.381 -17.536 1.00 55.32 ? 629 TRP A CD1 1 ATOM 4359 C CD2 . TRP A 1 629 ? -19.733 -6.160 -17.689 1.00 57.46 ? 629 TRP A CD2 1 ATOM 4360 N NE1 . TRP A 1 629 ? -20.526 -8.114 -18.445 1.00 60.21 ? 629 TRP A NE1 1 ATOM 4361 C CE2 . TRP A 1 629 ? -20.671 -6.756 -18.554 1.00 59.55 ? 629 TRP A CE2 1 ATOM 4362 C CE3 . TRP A 1 629 ? -19.676 -4.765 -17.613 1.00 58.19 ? 629 TRP A CE3 1 ATOM 4363 C CZ2 . TRP A 1 629 ? -21.545 -6.004 -19.337 1.00 52.33 ? 629 TRP A CZ2 1 ATOM 4364 C CZ3 . TRP A 1 629 ? -20.544 -4.023 -18.391 1.00 57.45 ? 629 TRP A CZ3 1 ATOM 4365 C CH2 . TRP A 1 629 ? -21.463 -4.641 -19.241 1.00 51.88 ? 629 TRP A CH2 1 ATOM 4366 N N . THR A 1 630 ? -18.204 -9.081 -14.076 1.00 46.17 ? 630 THR A N 1 ATOM 4367 C CA . THR A 1 630 ? -18.592 -10.337 -13.444 1.00 50.05 ? 630 THR A CA 1 ATOM 4368 C C . THR A 1 630 ? -18.145 -10.403 -11.992 1.00 58.70 ? 630 THR A C 1 ATOM 4369 O O . THR A 1 630 ? -18.898 -10.822 -11.114 1.00 68.97 ? 630 THR A O 1 ATOM 4370 C CB . THR A 1 630 ? -17.995 -11.530 -14.190 1.00 43.87 ? 630 THR A CB 1 ATOM 4371 O OG1 . THR A 1 630 ? -17.423 -11.070 -15.416 1.00 44.21 ? 630 THR A OG1 1 ATOM 4372 C CG2 . THR A 1 630 ? -19.065 -12.567 -14.489 1.00 40.91 ? 630 THR A CG2 1 ATOM 4373 N N . ALA A 1 631 ? -16.908 -9.979 -11.753 1.00 60.09 ? 631 ALA A N 1 ATOM 4374 C CA . ALA A 1 631 ? -16.279 -10.118 -10.445 1.00 60.28 ? 631 ALA A CA 1 ATOM 4375 C C . ALA A 1 631 ? -16.952 -9.252 -9.389 1.00 60.27 ? 631 ALA A C 1 ATOM 4376 O O . ALA A 1 631 ? -16.964 -9.598 -8.209 1.00 58.92 ? 631 ALA A O 1 ATOM 4377 C CB . ALA A 1 631 ? -14.795 -9.795 -10.537 1.00 60.26 ? 631 ALA A CB 1 ATOM 4378 N N . LYS A 1 632 ? -17.512 -8.127 -9.819 1.00 60.19 ? 632 LYS A N 1 ATOM 4379 C CA . LYS A 1 632 ? -18.183 -7.212 -8.906 1.00 63.45 ? 632 LYS A CA 1 ATOM 4380 C C . LYS A 1 632 ? -19.626 -7.629 -8.640 1.00 72.68 ? 632 LYS A C 1 ATOM 4381 O O . LYS A 1 632 ? -20.269 -7.109 -7.727 1.00 72.79 ? 632 LYS A O 1 ATOM 4382 C CB . LYS A 1 632 ? -18.157 -5.791 -9.462 1.00 65.61 ? 632 LYS A CB 1 ATOM 4383 C CG . LYS A 1 632 ? -17.799 -4.726 -8.446 1.00 64.68 ? 632 LYS A CG 1 ATOM 4384 C CD . LYS A 1 632 ? -16.349 -4.842 -8.013 1.00 64.21 ? 632 LYS A CD 1 ATOM 4385 C CE . LYS A 1 632 ? -15.989 -3.738 -7.036 1.00 82.33 ? 632 LYS A CE 1 ATOM 4386 N NZ . LYS A 1 632 ? -16.375 -2.397 -7.557 1.00 86.40 ? 632 LYS A NZ 1 ATOM 4387 N N . ASP A 1 633 ? -20.136 -8.569 -9.431 1.00 74.80 ? 633 ASP A N 1 ATOM 4388 C CA . ASP A 1 633 ? -21.495 -9.049 -9.223 1.00 70.19 ? 633 ASP A CA 1 ATOM 4389 C C . ASP A 1 633 ? -21.487 -9.927 -7.983 1.00 67.88 ? 633 ASP A C 1 ATOM 4390 O O . ASP A 1 633 ? -20.788 -10.938 -7.927 1.00 67.48 ? 633 ASP A O 1 ATOM 4391 C CB . ASP A 1 633 ? -21.991 -9.836 -10.442 1.00 67.18 ? 633 ASP A CB 1 ATOM 4392 C CG . ASP A 1 633 ? -23.459 -10.230 -10.336 1.00 73.86 ? 633 ASP A CG 1 ATOM 4393 O OD1 . ASP A 1 633 ? -23.880 -10.751 -9.281 1.00 73.79 ? 633 ASP A OD1 1 ATOM 4394 O OD2 . ASP A 1 633 ? -24.199 -10.027 -11.320 1.00 76.22 ? 633 ASP A OD2 1 ATOM 4395 N N . LEU A 1 634 ? -22.279 -9.535 -6.994 1.00 66.15 ? 634 LEU A N 1 ATOM 4396 C CA . LEU A 1 634 ? -22.306 -10.223 -5.713 1.00 68.37 ? 634 LEU A CA 1 ATOM 4397 C C . LEU A 1 634 ? -23.146 -11.489 -5.813 1.00 71.26 ? 634 LEU A C 1 ATOM 4398 O O . LEU A 1 634 ? -22.824 -12.511 -5.206 1.00 72.68 ? 634 LEU A O 1 ATOM 4399 C CB . LEU A 1 634 ? -22.847 -9.291 -4.630 1.00 66.73 ? 634 LEU A CB 1 ATOM 4400 C CG . LEU A 1 634 ? -22.127 -7.942 -4.529 1.00 65.72 ? 634 LEU A CG 1 ATOM 4401 C CD1 . LEU A 1 634 ? -22.884 -6.980 -3.626 1.00 67.46 ? 634 LEU A CD1 1 ATOM 4402 C CD2 . LEU A 1 634 ? -20.698 -8.125 -4.038 1.00 57.25 ? 634 LEU A CD2 1 ATOM 4403 N N . HIS A 1 635 ? -24.220 -11.415 -6.594 1.00 68.90 ? 635 HIS A N 1 ATOM 4404 C CA . HIS A 1 635 ? -25.097 -12.563 -6.796 1.00 73.62 ? 635 HIS A CA 1 ATOM 4405 C C . HIS A 1 635 ? -24.403 -13.685 -7.570 1.00 72.94 ? 635 HIS A C 1 ATOM 4406 O O . HIS A 1 635 ? -24.582 -14.861 -7.254 1.00 73.21 ? 635 HIS A O 1 ATOM 4407 C CB . HIS A 1 635 ? -26.388 -12.145 -7.504 1.00 76.85 ? 635 HIS A CB 1 ATOM 4408 C CG . HIS A 1 635 ? -27.236 -13.300 -7.938 1.00 80.18 ? 635 HIS A CG 1 ATOM 4409 N ND1 . HIS A 1 635 ? -27.619 -14.306 -7.077 1.00 79.98 ? 635 HIS A ND1 1 ATOM 4410 C CD2 . HIS A 1 635 ? -27.767 -13.614 -9.143 1.00 74.29 ? 635 HIS A CD2 1 ATOM 4411 C CE1 . HIS A 1 635 ? -28.351 -15.188 -7.733 1.00 80.39 ? 635 HIS A CE1 1 ATOM 4412 N NE2 . HIS A 1 635 ? -28.456 -14.792 -8.988 1.00 74.71 ? 635 HIS A NE2 1 ATOM 4413 N N . ILE A 1 636 ? -23.614 -13.319 -8.579 1.00 69.66 ? 636 ILE A N 1 ATOM 4414 C CA . ILE A 1 636 ? -22.855 -14.299 -9.354 1.00 67.46 ? 636 ILE A CA 1 ATOM 4415 C C . ILE A 1 636 ? -21.842 -15.018 -8.465 1.00 70.19 ? 636 ILE A C 1 ATOM 4416 O O . ILE A 1 636 ? -21.675 -16.236 -8.552 1.00 71.04 ? 636 ILE A O 1 ATOM 4417 C CB . ILE A 1 636 ? -22.136 -13.644 -10.560 1.00 64.06 ? 636 ILE A CB 1 ATOM 4418 C CG1 . ILE A 1 636 ? -23.138 -13.314 -11.669 1.00 70.54 ? 636 ILE A CG1 1 ATOM 4419 C CG2 . ILE A 1 636 ? -21.062 -14.563 -11.113 1.00 64.15 ? 636 ILE A CG2 1 ATOM 4420 C CD1 . ILE A 1 636 ? -22.522 -12.607 -12.866 1.00 71.61 ? 636 ILE A CD1 1 ATOM 4421 N N . LEU A 1 637 ? -21.175 -14.254 -7.605 1.00 71.69 ? 637 LEU A N 1 ATOM 4422 C CA . LEU A 1 637 ? -20.196 -14.810 -6.675 1.00 72.05 ? 637 LEU A CA 1 ATOM 4423 C C . LEU A 1 637 ? -20.820 -15.778 -5.671 1.00 72.46 ? 637 LEU A C 1 ATOM 4424 O O . LEU A 1 637 ? -20.414 -16.936 -5.582 1.00 74.91 ? 637 LEU A O 1 ATOM 4425 C CB . LEU A 1 637 ? -19.469 -13.690 -5.923 1.00 73.33 ? 637 LEU A CB 1 ATOM 4426 C CG . LEU A 1 637 ? -18.515 -12.799 -6.721 1.00 67.78 ? 637 LEU A CG 1 ATOM 4427 C CD1 . LEU A 1 637 ? -17.796 -11.810 -5.813 1.00 75.53 ? 637 LEU A CD1 1 ATOM 4428 C CD2 . LEU A 1 637 ? -17.518 -13.648 -7.476 1.00 61.00 ? 637 LEU A CD2 1 ATOM 4429 N N . HIS A 1 638 ? -21.813 -15.296 -4.927 1.00 66.84 ? 638 HIS A N 1 ATOM 4430 C CA . HIS A 1 638 ? -22.417 -16.056 -3.831 1.00 69.19 ? 638 HIS A CA 1 ATOM 4431 C C . HIS A 1 638 ? -22.868 -17.464 -4.222 1.00 74.28 ? 638 HIS A C 1 ATOM 4432 O O . HIS A 1 638 ? -22.746 -18.402 -3.435 1.00 78.55 ? 638 HIS A O 1 ATOM 4433 C CB . HIS A 1 638 ? -23.591 -15.281 -3.226 1.00 74.38 ? 638 HIS A CB 1 ATOM 4434 C CG . HIS A 1 638 ? -23.178 -14.168 -2.312 1.00 75.14 ? 638 HIS A CG 1 ATOM 4435 N ND1 . HIS A 1 638 ? -22.952 -12.883 -2.755 1.00 74.31 ? 638 HIS A ND1 1 ATOM 4436 C CD2 . HIS A 1 638 ? -22.956 -14.150 -0.976 1.00 72.26 ? 638 HIS A CD2 1 ATOM 4437 C CE1 . HIS A 1 638 ? -22.607 -12.121 -1.732 1.00 70.69 ? 638 HIS A CE1 1 ATOM 4438 N NE2 . HIS A 1 638 ? -22.601 -12.865 -0.642 1.00 70.27 ? 638 HIS A NE2 1 ATOM 4439 N N . THR A 1 639 ? -23.383 -17.606 -5.438 1.00 74.44 ? 639 THR A N 1 ATOM 4440 C CA . THR A 1 639 ? -23.886 -18.892 -5.908 1.00 72.45 ? 639 THR A CA 1 ATOM 4441 C C . THR A 1 639 ? -22.767 -19.856 -6.307 1.00 70.71 ? 639 THR A C 1 ATOM 4442 O O . THR A 1 639 ? -22.775 -21.023 -5.916 1.00 69.51 ? 639 THR A O 1 ATOM 4443 C CB . THR A 1 639 ? -24.836 -18.716 -7.106 1.00 72.98 ? 639 THR A CB 1 ATOM 4444 O OG1 . THR A 1 639 ? -24.119 -18.128 -8.198 1.00 68.77 ? 639 THR A OG1 1 ATOM 4445 C CG2 . THR A 1 639 ? -26.013 -17.820 -6.733 1.00 74.21 ? 639 THR A CG2 1 ATOM 4446 N N . HIS A 1 640 ? -21.814 -19.366 -7.096 1.00 72.55 ? 640 HIS A N 1 ATOM 4447 C CA . HIS A 1 640 ? -20.754 -20.215 -7.642 1.00 77.28 ? 640 HIS A CA 1 ATOM 4448 C C . HIS A 1 640 ? -19.519 -20.392 -6.751 1.00 74.06 ? 640 HIS A C 1 ATOM 4449 O O . HIS A 1 640 ? -18.730 -21.315 -6.960 1.00 71.00 ? 640 HIS A O 1 ATOM 4450 C CB . HIS A 1 640 ? -20.338 -19.710 -9.026 1.00 74.40 ? 640 HIS A CB 1 ATOM 4451 C CG . HIS A 1 640 ? -21.437 -19.765 -10.040 1.00 68.95 ? 640 HIS A CG 1 ATOM 4452 N ND1 . HIS A 1 640 ? -21.485 -18.923 -11.130 1.00 64.73 ? 640 HIS A ND1 1 ATOM 4453 C CD2 . HIS A 1 640 ? -22.528 -20.561 -10.131 1.00 68.66 ? 640 HIS A CD2 1 ATOM 4454 C CE1 . HIS A 1 640 ? -22.560 -19.198 -11.849 1.00 68.90 ? 640 HIS A CE1 1 ATOM 4455 N NE2 . HIS A 1 640 ? -23.209 -20.189 -11.263 1.00 76.14 ? 640 HIS A NE2 1 ATOM 4456 N N . VAL A 1 641 ? -19.350 -19.516 -5.765 1.00 69.41 ? 641 VAL A N 1 ATOM 4457 C CA . VAL A 1 641 ? -18.258 -19.658 -4.801 1.00 65.13 ? 641 VAL A CA 1 ATOM 4458 C C . VAL A 1 641 ? -18.682 -19.280 -3.381 1.00 73.49 ? 641 VAL A C 1 ATOM 4459 O O . VAL A 1 641 ? -18.215 -18.279 -2.837 1.00 75.21 ? 641 VAL A O 1 ATOM 4460 C CB . VAL A 1 641 ? -16.997 -18.850 -5.212 1.00 59.39 ? 641 VAL A CB 1 ATOM 4461 C CG1 . VAL A 1 641 ? -16.132 -19.652 -6.167 1.00 61.58 ? 641 VAL A CG1 1 ATOM 4462 C CG2 . VAL A 1 641 ? -17.377 -17.515 -5.827 1.00 54.81 ? 641 VAL A CG2 1 ATOM 4463 N N . PRO A 1 642 ? -19.566 -20.089 -2.770 1.00 76.86 ? 642 PRO A N 1 ATOM 4464 C CA . PRO A 1 642 ? -20.056 -19.795 -1.418 1.00 81.07 ? 642 PRO A CA 1 ATOM 4465 C C . PRO A 1 642 ? -18.940 -19.937 -0.392 1.00 86.70 ? 642 PRO A C 1 ATOM 4466 O O . PRO A 1 642 ? -18.961 -19.268 0.642 1.00 88.11 ? 642 PRO A O 1 ATOM 4467 C CB . PRO A 1 642 ? -21.117 -20.882 -1.180 1.00 77.83 ? 642 PRO A CB 1 ATOM 4468 C CG . PRO A 1 642 ? -21.392 -21.485 -2.526 1.00 80.27 ? 642 PRO A CG 1 ATOM 4469 C CD . PRO A 1 642 ? -20.118 -21.351 -3.290 1.00 75.02 ? 642 PRO A CD 1 ATOM 4470 N N . GLU A 1 643 ? -17.975 -20.802 -0.697 1.00 85.36 ? 643 GLU A N 1 ATOM 4471 C CA . GLU A 1 643 ? -16.848 -21.087 0.186 1.00 85.58 ? 643 GLU A CA 1 ATOM 4472 C C . GLU A 1 643 ? -16.076 -19.829 0.566 1.00 83.70 ? 643 GLU A C 1 ATOM 4473 O O . GLU A 1 643 ? -15.661 -19.667 1.714 1.00 90.69 ? 643 GLU A O 1 ATOM 4474 C CB . GLU A 1 643 ? -15.904 -22.081 -0.487 1.00 85.66 ? 643 GLU A CB 1 ATOM 4475 C CG . GLU A 1 643 ? -16.612 -23.168 -1.273 1.00 86.21 ? 643 GLU A CG 1 ATOM 4476 C CD . GLU A 1 643 ? -15.935 -23.443 -2.597 1.00 89.04 ? 643 GLU A CD 1 ATOM 4477 O OE1 . GLU A 1 643 ? -14.953 -22.740 -2.912 1.00 88.01 ? 643 GLU A OE1 1 ATOM 4478 O OE2 . GLU A 1 643 ? -16.383 -24.353 -3.326 1.00 91.15 ? 643 GLU A OE2 1 ATOM 4479 N N . VAL A 1 644 ? -15.881 -18.949 -0.411 1.00 72.99 ? 644 VAL A N 1 ATOM 4480 C CA . VAL A 1 644 ? -15.205 -17.676 -0.193 1.00 71.22 ? 644 VAL A CA 1 ATOM 4481 C C . VAL A 1 644 ? -15.899 -16.867 0.903 1.00 77.45 ? 644 VAL A C 1 ATOM 4482 O O . VAL A 1 644 ? -15.249 -16.204 1.712 1.00 81.66 ? 644 VAL A O 1 ATOM 4483 C CB . VAL A 1 644 ? -15.170 -16.850 -1.499 1.00 66.22 ? 644 VAL A CB 1 ATOM 4484 C CG1 . VAL A 1 644 ? -14.568 -15.476 -1.261 1.00 64.88 ? 644 VAL A CG1 1 ATOM 4485 C CG2 . VAL A 1 644 ? -14.395 -17.597 -2.573 1.00 60.26 ? 644 VAL A CG2 1 ATOM 4486 N N . PHE A 1 645 ? -17.225 -16.939 0.926 1.00 82.31 ? 645 PHE A N 1 ATOM 4487 C CA . PHE A 1 645 ? -18.038 -16.140 1.839 1.00 86.54 ? 645 PHE A CA 1 ATOM 4488 C C . PHE A 1 645 ? -18.492 -16.862 3.114 1.00 84.47 ? 645 PHE A C 1 ATOM 4489 O O . PHE A 1 645 ? -19.159 -16.257 3.953 1.00 84.48 ? 645 PHE A O 1 ATOM 4490 C CB . PHE A 1 645 ? -19.270 -15.602 1.101 1.00 90.38 ? 645 PHE A CB 1 ATOM 4491 C CG . PHE A 1 645 ? -18.945 -14.727 -0.079 1.00 81.83 ? 645 PHE A CG 1 ATOM 4492 C CD1 . PHE A 1 645 ? -19.006 -13.347 0.029 1.00 79.83 ? 645 PHE A CD1 1 ATOM 4493 C CD2 . PHE A 1 645 ? -18.593 -15.283 -1.300 1.00 73.46 ? 645 PHE A CD2 1 ATOM 4494 C CE1 . PHE A 1 645 ? -18.713 -12.538 -1.053 1.00 77.53 ? 645 PHE A CE1 1 ATOM 4495 C CE2 . PHE A 1 645 ? -18.298 -14.479 -2.386 1.00 71.94 ? 645 PHE A CE2 1 ATOM 4496 C CZ . PHE A 1 645 ? -18.358 -13.105 -2.262 1.00 73.98 ? 645 PHE A CZ 1 ATOM 4497 N N . THR A 1 646 ? -18.138 -18.138 3.257 1.00 84.46 ? 646 THR A N 1 ATOM 4498 C CA . THR A 1 646 ? -18.740 -19.001 4.284 1.00 92.96 ? 646 THR A CA 1 ATOM 4499 C C . THR A 1 646 ? -18.659 -18.494 5.723 1.00 105.83 ? 646 THR A C 1 ATOM 4500 O O . THR A 1 646 ? -19.670 -18.084 6.295 1.00 110.86 ? 646 THR A O 1 ATOM 4501 C CB . THR A 1 646 ? -18.166 -20.426 4.238 1.00 90.80 ? 646 THR A CB 1 ATOM 4502 O OG1 . THR A 1 646 ? -16.753 -20.369 4.002 1.00 84.97 ? 646 THR A OG1 1 ATOM 4503 C CG2 . THR A 1 646 ? -18.832 -21.223 3.137 1.00 92.20 ? 646 THR A CG2 1 ATOM 4504 N N . CYS A 1 647 ? -17.468 -18.529 6.311 1.00 101.62 ? 647 CYS A N 1 ATOM 4505 C CA . CYS A 1 647 ? -17.279 -17.964 7.641 1.00 97.66 ? 647 CYS A CA 1 ATOM 4506 C C . CYS A 1 647 ? -17.305 -16.456 7.499 1.00 86.99 ? 647 CYS A C 1 ATOM 4507 O O . CYS A 1 647 ? -17.085 -15.942 6.401 1.00 83.99 ? 647 CYS A O 1 ATOM 4508 C CB . CYS A 1 647 ? -15.952 -18.415 8.249 1.00 103.87 ? 647 CYS A CB 1 ATOM 4509 S SG . CYS A 1 647 ? -16.106 -19.726 9.486 1.00 153.42 ? 647 CYS A SG 1 ATOM 4510 N N . GLN A 1 648 ? -17.588 -15.748 8.590 1.00 72.52 ? 648 GLN A N 1 ATOM 4511 C CA . GLN A 1 648 ? -17.638 -14.296 8.525 1.00 67.98 ? 648 GLN A CA 1 ATOM 4512 C C . GLN A 1 648 ? -16.293 -13.825 8.001 1.00 76.49 ? 648 GLN A C 1 ATOM 4513 O O . GLN A 1 648 ? -15.252 -14.100 8.595 1.00 91.37 ? 648 GLN A O 1 ATOM 4514 C CB . GLN A 1 648 ? -17.917 -13.709 9.895 1.00 51.44 ? 648 GLN A CB 1 ATOM 4515 N N . ASP A 1 649 ? -16.323 -13.110 6.884 1.00 70.71 ? 649 ASP A N 1 ATOM 4516 C CA . ASP A 1 649 ? -15.100 -12.804 6.162 1.00 72.19 ? 649 ASP A CA 1 ATOM 4517 C C . ASP A 1 649 ? -15.112 -11.365 5.681 1.00 77.63 ? 649 ASP A C 1 ATOM 4518 O O . ASP A 1 649 ? -16.021 -10.946 4.967 1.00 80.98 ? 649 ASP A O 1 ATOM 4519 C CB . ASP A 1 649 ? -14.937 -13.762 4.976 1.00 71.57 ? 649 ASP A CB 1 ATOM 4520 C CG . ASP A 1 649 ? -13.533 -13.748 4.395 1.00 76.55 ? 649 ASP A CG 1 ATOM 4521 O OD1 . ASP A 1 649 ? -13.014 -12.654 4.092 1.00 73.32 ? 649 ASP A OD1 1 ATOM 4522 O OD2 . ASP A 1 649 ? -12.946 -14.839 4.242 1.00 75.90 ? 649 ASP A OD2 1 ATOM 4523 N N . ALA A 1 650 ? -14.094 -10.613 6.081 1.00 85.93 ? 650 ALA A N 1 ATOM 4524 C CA . ALA A 1 650 ? -13.945 -9.240 5.631 1.00 88.82 ? 650 ALA A CA 1 ATOM 4525 C C . ALA A 1 650 ? -13.500 -9.214 4.176 1.00 82.92 ? 650 ALA A C 1 ATOM 4526 O O . ALA A 1 650 ? -14.108 -8.540 3.348 1.00 85.63 ? 650 ALA A O 1 ATOM 4527 C CB . ALA A 1 650 ? -12.951 -8.497 6.510 1.00 92.79 ? 650 ALA A CB 1 ATOM 4528 N N . ALA A 1 651 ? -12.450 -9.973 3.875 1.00 80.36 ? 651 ALA A N 1 ATOM 4529 C CA . ALA A 1 651 ? -11.832 -9.981 2.549 1.00 81.19 ? 651 ALA A CA 1 ATOM 4530 C C . ALA A 1 651 ? -12.813 -10.226 1.401 1.00 81.69 ? 651 ALA A C 1 ATOM 4531 O O . ALA A 1 651 ? -12.656 -9.671 0.314 1.00 76.53 ? 651 ALA A O 1 ATOM 4532 C CB . ALA A 1 651 ? -10.697 -10.996 2.503 1.00 74.70 ? 651 ALA A CB 1 ATOM 4533 N N . ALA A 1 652 ? -13.820 -11.056 1.649 1.00 82.19 ? 652 ALA A N 1 ATOM 4534 C CA . ALA A 1 652 ? -14.840 -11.333 0.646 1.00 79.01 ? 652 ALA A CA 1 ATOM 4535 C C . ALA A 1 652 ? -15.646 -10.081 0.306 1.00 82.79 ? 652 ALA A C 1 ATOM 4536 O O . ALA A 1 652 ? -15.781 -9.719 -0.863 1.00 89.49 ? 652 ALA A O 1 ATOM 4537 C CB . ALA A 1 652 ? -15.759 -12.448 1.119 1.00 77.08 ? 652 ALA A CB 1 ATOM 4538 N N . ARG A 1 653 ? -16.181 -9.423 1.330 1.00 80.47 ? 653 ARG A N 1 ATOM 4539 C CA . ARG A 1 653 ? -17.043 -8.264 1.117 1.00 84.57 ? 653 ARG A CA 1 ATOM 4540 C C . ARG A 1 653 ? -16.282 -6.938 1.097 1.00 83.33 ? 653 ARG A C 1 ATOM 4541 O O . ARG A 1 653 ? -16.853 -5.900 0.764 1.00 84.92 ? 653 ARG A O 1 ATOM 4542 C CB . ARG A 1 653 ? -18.160 -8.222 2.167 1.00 99.08 ? 653 ARG A CB 1 ATOM 4543 C CG . ARG A 1 653 ? -19.539 -7.924 1.589 1.00 114.33 ? 653 ARG A CG 1 ATOM 4544 C CD . ARG A 1 653 ? -20.627 -7.998 2.654 1.00 118.90 ? 653 ARG A CD 1 ATOM 4545 N NE . ARG A 1 653 ? -20.606 -6.844 3.547 1.00 122.51 ? 653 ARG A NE 1 ATOM 4546 C CZ . ARG A 1 653 ? -21.328 -5.742 3.364 1.00 127.99 ? 653 ARG A CZ 1 ATOM 4547 N NH1 . ARG A 1 653 ? -22.136 -5.637 2.318 1.00 128.23 ? 653 ARG A NH1 1 ATOM 4548 N NH2 . ARG A 1 653 ? -21.241 -4.743 4.230 1.00 121.95 ? 653 ARG A NH2 1 ATOM 4549 N N . ASN A 1 654 ? -15.004 -6.968 1.462 1.00 82.86 ? 654 ASN A N 1 ATOM 4550 C CA . ASN A 1 654 ? -14.172 -5.768 1.398 1.00 83.51 ? 654 ASN A CA 1 ATOM 4551 C C . ASN A 1 654 ? -13.358 -5.695 0.113 1.00 73.87 ? 654 ASN A C 1 ATOM 4552 O O . ASN A 1 654 ? -12.663 -4.710 -0.137 1.00 68.06 ? 654 ASN A O 1 ATOM 4553 C CB . ASN A 1 654 ? -13.240 -5.678 2.610 1.00 85.95 ? 654 ASN A CB 1 ATOM 4554 C CG . ASN A 1 654 ? -13.977 -5.342 3.892 1.00 91.69 ? 654 ASN A CG 1 ATOM 4555 O OD1 . ASN A 1 654 ? -13.839 -4.243 4.428 1.00 97.47 ? 654 ASN A OD1 1 ATOM 4556 N ND2 . ASN A 1 654 ? -14.767 -6.286 4.388 1.00 94.93 ? 654 ASN A ND2 1 ATOM 4557 N N . GLY A 1 655 ? -13.451 -6.739 -0.703 1.00 73.80 ? 655 GLY A N 1 ATOM 4558 C CA . GLY A 1 655 ? -12.718 -6.794 -1.954 1.00 79.93 ? 655 GLY A CA 1 ATOM 4559 C C . GLY A 1 655 ? -11.227 -6.991 -1.756 1.00 76.28 ? 655 GLY A C 1 ATOM 4560 O O . GLY A 1 655 ? -10.432 -6.717 -2.657 1.00 72.17 ? 655 GLY A O 1 ATOM 4561 N N . GLU A 1 656 ? -10.845 -7.467 -0.574 1.00 74.99 ? 656 GLU A N 1 ATOM 4562 C CA . GLU A 1 656 ? -9.440 -7.728 -0.280 1.00 79.87 ? 656 GLU A CA 1 ATOM 4563 C C . GLU A 1 656 ? -8.938 -8.929 -1.069 1.00 75.26 ? 656 GLU A C 1 ATOM 4564 O O . GLU A 1 656 ? -7.737 -9.068 -1.307 1.00 77.82 ? 656 GLU A O 1 ATOM 4565 C CB . GLU A 1 656 ? -9.218 -7.956 1.215 1.00 79.83 ? 656 GLU A CB 1 ATOM 4566 C CG . GLU A 1 656 ? -9.380 -6.713 2.074 1.00 80.02 ? 656 GLU A CG 1 ATOM 4567 C CD . GLU A 1 656 ? -9.049 -6.974 3.530 1.00 84.84 ? 656 GLU A CD 1 ATOM 4568 O OE1 . GLU A 1 656 ? -8.944 -8.159 3.914 1.00 85.32 ? 656 GLU A OE1 1 ATOM 4569 O OE2 . GLU A 1 656 ? -8.886 -5.997 4.290 1.00 89.42 ? 656 GLU A OE2 1 ATOM 4570 N N . TYR A 1 657 ? -9.860 -9.795 -1.475 1.00 65.15 ? 657 TYR A N 1 ATOM 4571 C CA . TYR A 1 657 ? -9.500 -10.893 -2.349 1.00 55.62 ? 657 TYR A CA 1 ATOM 4572 C C . TYR A 1 657 ? -9.385 -10.292 -3.740 1.00 59.75 ? 657 TYR A C 1 ATOM 4573 O O . TYR A 1 657 ? -10.365 -9.804 -4.301 1.00 66.68 ? 657 TYR A O 1 ATOM 4574 C CB . TYR A 1 657 ? -10.590 -11.963 -2.332 1.00 58.23 ? 657 TYR A CB 1 ATOM 4575 C CG . TYR A 1 657 ? -10.679 -12.778 -1.054 1.00 62.17 ? 657 TYR A CG 1 ATOM 4576 C CD1 . TYR A 1 657 ? -9.539 -13.144 -0.352 1.00 65.84 ? 657 TYR A CD1 1 ATOM 4577 C CD2 . TYR A 1 657 ? -11.909 -13.191 -0.559 1.00 70.94 ? 657 TYR A CD2 1 ATOM 4578 C CE1 . TYR A 1 657 ? -9.624 -13.897 0.812 1.00 73.15 ? 657 TYR A CE1 1 ATOM 4579 C CE2 . TYR A 1 657 ? -12.003 -13.939 0.602 1.00 75.23 ? 657 TYR A CE2 1 ATOM 4580 C CZ . TYR A 1 657 ? -10.858 -14.290 1.283 1.00 69.35 ? 657 TYR A CZ 1 ATOM 4581 O OH . TYR A 1 657 ? -10.951 -15.035 2.438 1.00 55.76 ? 657 TYR A OH 1 ATOM 4582 N N . VAL A 1 658 ? -8.182 -10.334 -4.297 1.00 61.88 ? 658 VAL A N 1 ATOM 4583 C CA . VAL A 1 658 ? -7.911 -9.699 -5.582 1.00 62.81 ? 658 VAL A CA 1 ATOM 4584 C C . VAL A 1 658 ? -8.377 -10.580 -6.741 1.00 60.41 ? 658 VAL A C 1 ATOM 4585 O O . VAL A 1 658 ? -8.891 -10.086 -7.745 1.00 60.99 ? 658 VAL A O 1 ATOM 4586 C CB . VAL A 1 658 ? -6.417 -9.304 -5.717 1.00 57.25 ? 658 VAL A CB 1 ATOM 4587 C CG1 . VAL A 1 658 ? -5.779 -9.939 -6.940 1.00 58.60 ? 658 VAL A CG1 1 ATOM 4588 C CG2 . VAL A 1 658 ? -6.257 -7.789 -5.755 1.00 54.59 ? 658 VAL A CG2 1 ATOM 4589 N N . LEU A 1 659 ? -8.210 -11.888 -6.579 1.00 57.69 ? 659 LEU A N 1 ATOM 4590 C CA . LEU A 1 659 ? -8.517 -12.842 -7.635 1.00 51.79 ? 659 LEU A CA 1 ATOM 4591 C C . LEU A 1 659 ? -9.007 -14.153 -7.017 1.00 48.76 ? 659 LEU A C 1 ATOM 4592 O O . LEU A 1 659 ? -8.458 -14.610 -6.017 1.00 55.32 ? 659 LEU A O 1 ATOM 4593 C CB . LEU A 1 659 ? -7.263 -13.055 -8.491 1.00 43.39 ? 659 LEU A CB 1 ATOM 4594 C CG . LEU A 1 659 ? -7.226 -14.030 -9.662 1.00 42.99 ? 659 LEU A CG 1 ATOM 4595 C CD1 . LEU A 1 659 ? -6.271 -13.507 -10.713 1.00 43.42 ? 659 LEU A CD1 1 ATOM 4596 C CD2 . LEU A 1 659 ? -6.766 -15.387 -9.188 1.00 40.03 ? 659 LEU A CD2 1 ATOM 4597 N N . ILE A 1 660 ? -10.029 -14.761 -7.613 1.00 46.66 ? 660 ILE A N 1 ATOM 4598 C CA . ILE A 1 660 ? -10.599 -15.997 -7.072 1.00 47.83 ? 660 ILE A CA 1 ATOM 4599 C C . ILE A 1 660 ? -10.629 -17.111 -8.118 1.00 56.78 ? 660 ILE A C 1 ATOM 4600 O O . ILE A 1 660 ? -11.155 -16.926 -9.216 1.00 63.89 ? 660 ILE A O 1 ATOM 4601 C CB . ILE A 1 660 ? -12.034 -15.780 -6.532 1.00 44.45 ? 660 ILE A CB 1 ATOM 4602 C CG1 . ILE A 1 660 ? -12.107 -14.512 -5.678 1.00 42.49 ? 660 ILE A CG1 1 ATOM 4603 C CG2 . ILE A 1 660 ? -12.503 -16.995 -5.739 1.00 40.48 ? 660 ILE A CG2 1 ATOM 4604 C CD1 . ILE A 1 660 ? -13.488 -14.219 -5.128 1.00 36.11 ? 660 ILE A CD1 1 ATOM 4605 N N . LEU A 1 661 ? -10.059 -18.264 -7.777 1.00 55.49 ? 661 LEU A N 1 ATOM 4606 C CA . LEU A 1 661 ? -10.056 -19.415 -8.679 1.00 55.89 ? 661 LEU A CA 1 ATOM 4607 C C . LEU A 1 661 ? -10.833 -20.592 -8.100 1.00 61.37 ? 661 LEU A C 1 ATOM 4608 O O . LEU A 1 661 ? -10.414 -21.186 -7.106 1.00 62.13 ? 661 LEU A O 1 ATOM 4609 C CB . LEU A 1 661 ? -8.624 -19.841 -9.008 1.00 43.44 ? 661 LEU A CB 1 ATOM 4610 C CG . LEU A 1 661 ? -7.774 -18.746 -9.650 1.00 40.81 ? 661 LEU A CG 1 ATOM 4611 C CD1 . LEU A 1 661 ? -6.413 -19.272 -10.062 1.00 46.84 ? 661 LEU A CD1 1 ATOM 4612 C CD2 . LEU A 1 661 ? -8.501 -18.148 -10.838 1.00 49.68 ? 661 LEU A CD2 1 ATOM 4613 N N . PRO A 1 662 ? -11.983 -20.918 -8.709 1.00 60.51 ? 662 PRO A N 1 ATOM 4614 C CA . PRO A 1 662 ? -12.739 -22.081 -8.238 1.00 60.05 ? 662 PRO A CA 1 ATOM 4615 C C . PRO A 1 662 ? -11.955 -23.383 -8.382 1.00 62.72 ? 662 PRO A C 1 ATOM 4616 O O . PRO A 1 662 ? -11.481 -23.713 -9.468 1.00 63.65 ? 662 PRO A O 1 ATOM 4617 C CB . PRO A 1 662 ? -13.949 -22.103 -9.175 1.00 55.83 ? 662 PRO A CB 1 ATOM 4618 C CG . PRO A 1 662 ? -14.128 -20.682 -9.581 1.00 50.31 ? 662 PRO A CG 1 ATOM 4619 C CD . PRO A 1 662 ? -12.743 -20.117 -9.684 1.00 53.13 ? 662 PRO A CD 1 ATOM 4620 N N . ALA A 1 663 ? -11.835 -24.107 -7.276 1.00 68.07 ? 663 ALA A N 1 ATOM 4621 C CA . ALA A 1 663 ? -11.257 -25.447 -7.237 1.00 69.57 ? 663 ALA A CA 1 ATOM 4622 C C . ALA A 1 663 ? -12.376 -26.470 -7.360 1.00 70.93 ? 663 ALA A C 1 ATOM 4623 O O . ALA A 1 663 ? -13.474 -26.141 -7.808 1.00 75.66 ? 663 ALA A O 1 ATOM 4624 C CB . ALA A 1 663 ? -10.463 -25.661 -5.963 1.00 74.68 ? 663 ALA A CB 1 ATOM 4625 N N . VAL A 1 664 ? -12.098 -27.716 -6.988 1.00 69.12 ? 664 VAL A N 1 ATOM 4626 C CA . VAL A 1 664 ? -13.137 -28.737 -6.983 1.00 73.44 ? 664 VAL A CA 1 ATOM 4627 C C . VAL A 1 664 ? -14.152 -28.395 -5.891 1.00 77.76 ? 664 VAL A C 1 ATOM 4628 O O . VAL A 1 664 ? -13.985 -27.411 -5.172 1.00 73.53 ? 664 VAL A O 1 ATOM 4629 C CB . VAL A 1 664 ? -12.550 -30.127 -6.688 1.00 71.70 ? 664 VAL A CB 1 ATOM 4630 C CG1 . VAL A 1 664 ? -11.344 -30.391 -7.574 1.00 76.16 ? 664 VAL A CG1 1 ATOM 4631 C CG2 . VAL A 1 664 ? -12.157 -30.234 -5.225 1.00 75.34 ? 664 VAL A CG2 1 ATOM 4632 N N . GLN A 1 665 ? -15.195 -29.210 -5.760 1.00 84.03 ? 665 GLN A N 1 ATOM 4633 C CA . GLN A 1 665 ? -16.333 -28.876 -4.900 1.00 90.51 ? 665 GLN A CA 1 ATOM 4634 C C . GLN A 1 665 ? -15.953 -28.563 -3.451 1.00 88.85 ? 665 GLN A C 1 ATOM 4635 O O . GLN A 1 665 ? -15.145 -29.264 -2.843 1.00 89.99 ? 665 GLN A O 1 ATOM 4636 C CB . GLN A 1 665 ? -17.392 -29.983 -4.947 1.00 97.23 ? 665 GLN A CB 1 ATOM 4637 C CG . GLN A 1 665 ? -18.678 -29.649 -4.200 1.00 105.52 ? 665 GLN A CG 1 ATOM 4638 C CD . GLN A 1 665 ? -19.906 -30.244 -4.863 1.00 122.87 ? 665 GLN A CD 1 ATOM 4639 O OE1 . GLN A 1 665 ? -19.797 -31.030 -5.804 1.00 123.13 ? 665 GLN A OE1 1 ATOM 4640 N NE2 . GLN A 1 665 ? -21.084 -29.862 -4.381 1.00 123.50 ? 665 GLN A NE2 1 ATOM 4641 N N . GLY A 1 666 ? -16.533 -27.492 -2.917 1.00 89.28 ? 666 GLY A N 1 ATOM 4642 C CA . GLY A 1 666 ? -16.309 -27.099 -1.538 1.00 87.85 ? 666 GLY A CA 1 ATOM 4643 C C . GLY A 1 666 ? -15.035 -26.303 -1.326 1.00 91.07 ? 666 GLY A C 1 ATOM 4644 O O . GLY A 1 666 ? -14.791 -25.795 -0.231 1.00 95.03 ? 666 GLY A O 1 ATOM 4645 N N . HIS A 1 667 ? -14.223 -26.187 -2.373 1.00 86.03 ? 667 HIS A N 1 ATOM 4646 C CA . HIS A 1 667 ? -12.933 -25.514 -2.263 1.00 84.29 ? 667 HIS A CA 1 ATOM 4647 C C . HIS A 1 667 ? -12.663 -24.571 -3.435 1.00 78.04 ? 667 HIS A C 1 ATOM 4648 O O . HIS A 1 667 ? -13.112 -24.817 -4.553 1.00 75.84 ? 667 HIS A O 1 ATOM 4649 C CB . HIS A 1 667 ? -11.807 -26.545 -2.178 1.00 82.92 ? 667 HIS A CB 1 ATOM 4650 C CG . HIS A 1 667 ? -12.003 -27.580 -1.112 1.00 90.75 ? 667 HIS A CG 1 ATOM 4651 N ND1 . HIS A 1 667 ? -11.610 -27.389 0.195 1.00 90.01 ? 667 HIS A ND1 1 ATOM 4652 C CD2 . HIS A 1 667 ? -12.538 -28.823 -1.165 1.00 95.22 ? 667 HIS A CD2 1 ATOM 4653 C CE1 . HIS A 1 667 ? -11.902 -28.466 0.903 1.00 90.04 ? 667 HIS A CE1 1 ATOM 4654 N NE2 . HIS A 1 667 ? -12.465 -29.351 0.101 1.00 96.92 ? 667 HIS A NE2 1 ATOM 4655 N N . SER A 1 668 ? -11.946 -23.482 -3.162 1.00 72.88 ? 668 SER A N 1 ATOM 4656 C CA . SER A 1 668 ? -11.464 -22.570 -4.199 1.00 66.42 ? 668 SER A CA 1 ATOM 4657 C C . SER A 1 668 ? -10.204 -21.859 -3.725 1.00 65.45 ? 668 SER A C 1 ATOM 4658 O O . SER A 1 668 ? -10.053 -21.594 -2.534 1.00 70.83 ? 668 SER A O 1 ATOM 4659 C CB . SER A 1 668 ? -12.528 -21.528 -4.542 1.00 65.30 ? 668 SER A CB 1 ATOM 4660 O OG . SER A 1 668 ? -13.711 -22.149 -5.005 1.00 73.36 ? 668 SER A OG 1 ATOM 4661 N N . TYR A 1 669 ? -9.302 -21.540 -4.650 1.00 62.96 ? 669 TYR A N 1 ATOM 4662 C CA . TYR A 1 669 ? -8.136 -20.741 -4.293 1.00 60.46 ? 669 TYR A CA 1 ATOM 4663 C C . TYR A 1 669 ? -8.568 -19.292 -4.169 1.00 55.67 ? 669 TYR A C 1 ATOM 4664 O O . TYR A 1 669 ? -9.706 -18.951 -4.497 1.00 61.98 ? 669 TYR A O 1 ATOM 4665 C CB . TYR A 1 669 ? -7.069 -20.826 -5.385 1.00 60.93 ? 669 TYR A CB 1 ATOM 4666 C CG . TYR A 1 669 ? -6.240 -22.087 -5.385 1.00 63.30 ? 669 TYR A CG 1 ATOM 4667 C CD1 . TYR A 1 669 ? -6.097 -22.838 -6.540 1.00 67.51 ? 669 TYR A CD1 1 ATOM 4668 C CD2 . TYR A 1 669 ? -5.576 -22.510 -4.242 1.00 66.47 ? 669 TYR A CD2 1 ATOM 4669 C CE1 . TYR A 1 669 ? -5.338 -23.985 -6.557 1.00 65.98 ? 669 TYR A CE1 1 ATOM 4670 C CE2 . TYR A 1 669 ? -4.808 -23.659 -4.250 1.00 74.02 ? 669 TYR A CE2 1 ATOM 4671 C CZ . TYR A 1 669 ? -4.693 -24.390 -5.413 1.00 74.06 ? 669 TYR A CZ 1 ATOM 4672 O OH . TYR A 1 669 ? -3.933 -25.535 -5.437 1.00 81.22 ? 669 TYR A OH 1 ATOM 4673 N N . VAL A 1 670 ? -7.653 -18.437 -3.721 1.00 48.14 ? 670 VAL A N 1 ATOM 4674 C CA . VAL A 1 670 ? -7.874 -16.995 -3.755 1.00 48.06 ? 670 VAL A CA 1 ATOM 4675 C C . VAL A 1 670 ? -6.544 -16.233 -3.617 1.00 48.87 ? 670 VAL A C 1 ATOM 4676 O O . VAL A 1 670 ? -5.556 -16.790 -3.143 1.00 54.17 ? 670 VAL A O 1 ATOM 4677 C CB . VAL A 1 670 ? -8.940 -16.556 -2.710 1.00 47.69 ? 670 VAL A CB 1 ATOM 4678 C CG1 . VAL A 1 670 ? -8.341 -16.421 -1.334 1.00 56.84 ? 670 VAL A CG1 1 ATOM 4679 C CG2 . VAL A 1 670 ? -9.608 -15.269 -3.136 1.00 51.02 ? 670 VAL A CG2 1 ATOM 4680 N N . ILE A 1 671 ? -6.518 -14.972 -4.043 1.00 50.44 ? 671 ILE A N 1 ATOM 4681 C CA . ILE A 1 671 ? -5.324 -14.133 -3.921 1.00 51.75 ? 671 ILE A CA 1 ATOM 4682 C C . ILE A 1 671 ? -5.636 -12.913 -3.057 1.00 64.47 ? 671 ILE A C 1 ATOM 4683 O O . ILE A 1 671 ? -6.619 -12.215 -3.305 1.00 70.21 ? 671 ILE A O 1 ATOM 4684 C CB . ILE A 1 671 ? -4.812 -13.664 -5.303 1.00 46.85 ? 671 ILE A CB 1 ATOM 4685 C CG1 . ILE A 1 671 ? -4.163 -14.824 -6.059 1.00 48.43 ? 671 ILE A CG1 1 ATOM 4686 C CG2 . ILE A 1 671 ? -3.814 -12.522 -5.155 1.00 45.10 ? 671 ILE A CG2 1 ATOM 4687 C CD1 . ILE A 1 671 ? -2.855 -15.283 -5.461 1.00 52.79 ? 671 ILE A CD1 1 ATOM 4688 N N . THR A 1 672 ? -4.811 -12.662 -2.042 1.00 65.31 ? 672 THR A N 1 ATOM 4689 C CA . THR A 1 672 ? -5.038 -11.535 -1.136 1.00 66.51 ? 672 THR A CA 1 ATOM 4690 C C . THR A 1 672 ? -3.773 -10.713 -0.874 1.00 73.42 ? 672 THR A C 1 ATOM 4691 O O . THR A 1 672 ? -2.673 -11.259 -0.772 1.00 73.43 ? 672 THR A O 1 ATOM 4692 C CB . THR A 1 672 ? -5.660 -11.995 0.205 1.00 61.64 ? 672 THR A CB 1 ATOM 4693 O OG1 . THR A 1 672 ? -5.766 -10.879 1.099 1.00 64.81 ? 672 THR A OG1 1 ATOM 4694 C CG2 . THR A 1 672 ? -4.814 -13.079 0.849 1.00 62.88 ? 672 THR A CG2 1 ATOM 4695 N N . ARG A 1 673 ? -3.942 -9.395 -0.797 1.00 76.27 ? 673 ARG A N 1 ATOM 4696 C CA . ARG A 1 673 ? -2.837 -8.480 -0.517 1.00 82.32 ? 673 ARG A CA 1 ATOM 4697 C C . ARG A 1 673 ? -2.469 -8.412 0.966 1.00 83.90 ? 673 ARG A C 1 ATOM 4698 O O . ARG A 1 673 ? -1.296 -8.497 1.325 1.00 83.32 ? 673 ARG A O 1 ATOM 4699 C CB . ARG A 1 673 ? -3.164 -7.075 -1.034 1.00 83.85 ? 673 ARG A CB 1 ATOM 4700 C CG . ARG A 1 673 ? -2.929 -6.876 -2.525 1.00 84.50 ? 673 ARG A CG 1 ATOM 4701 C CD . ARG A 1 673 ? -1.482 -7.161 -2.893 1.00 69.74 ? 673 ARG A CD 1 ATOM 4702 N NE . ARG A 1 673 ? -1.095 -6.548 -4.160 1.00 70.41 ? 673 ARG A NE 1 ATOM 4703 C CZ . ARG A 1 673 ? -1.261 -7.116 -5.350 1.00 73.00 ? 673 ARG A CZ 1 ATOM 4704 N NH1 . ARG A 1 673 ? -1.817 -8.314 -5.443 1.00 71.00 ? 673 ARG A NH1 1 ATOM 4705 N NH2 . ARG A 1 673 ? -0.873 -6.482 -6.447 1.00 77.76 ? 673 ARG A NH2 1 ATOM 4706 N N . ASN A 1 674 ? -3.473 -8.257 1.823 1.00 80.56 ? 674 ASN A N 1 ATOM 4707 C CA . ASN A 1 674 ? -3.235 -8.130 3.260 1.00 76.86 ? 674 ASN A CA 1 ATOM 4708 C C . ASN A 1 674 ? -3.274 -9.460 4.005 1.00 71.07 ? 674 ASN A C 1 ATOM 4709 O O . ASN A 1 674 ? -3.328 -10.525 3.391 1.00 64.14 ? 674 ASN A O 1 ATOM 4710 C CB . ASN A 1 674 ? -4.212 -7.135 3.892 1.00 89.50 ? 674 ASN A CB 1 ATOM 4711 C CG . ASN A 1 674 ? -5.635 -7.337 3.419 1.00 99.09 ? 674 ASN A CG 1 ATOM 4712 O OD1 . ASN A 1 674 ? -6.140 -6.573 2.596 1.00 99.31 ? 674 ASN A OD1 1 ATOM 4713 N ND2 . ASN A 1 674 ? -6.289 -8.372 3.932 1.00 98.24 ? 674 ASN A ND2 1 ATOM 4714 N N . LYS A 1 675 ? -3.246 -9.386 5.332 1.00 75.13 ? 675 LYS A N 1 ATOM 4715 C CA . LYS A 1 675 ? -3.169 -10.574 6.174 1.00 79.52 ? 675 LYS A CA 1 ATOM 4716 C C . LYS A 1 675 ? -4.431 -11.424 6.069 1.00 78.13 ? 675 LYS A C 1 ATOM 4717 O O . LYS A 1 675 ? -5.514 -10.986 6.460 1.00 82.10 ? 675 LYS A O 1 ATOM 4718 C CB . LYS A 1 675 ? -2.927 -10.170 7.633 1.00 85.96 ? 675 LYS A CB 1 ATOM 4719 C CG . LYS A 1 675 ? -2.533 -11.317 8.554 1.00 93.74 ? 675 LYS A CG 1 ATOM 4720 C CD . LYS A 1 675 ? -2.264 -10.814 9.966 1.00 104.66 ? 675 LYS A CD 1 ATOM 4721 C CE . LYS A 1 675 ? -1.689 -11.909 10.850 1.00 106.99 ? 675 LYS A CE 1 ATOM 4722 N NZ . LYS A 1 675 ? -2.606 -13.075 10.962 1.00 107.13 ? 675 LYS A NZ 1 ATOM 4723 N N . PRO A 1 676 ? -4.290 -12.654 5.551 1.00 73.39 ? 676 PRO A N 1 ATOM 4724 C CA . PRO A 1 676 ? -5.415 -13.589 5.431 1.00 82.67 ? 676 PRO A CA 1 ATOM 4725 C C . PRO A 1 676 ? -5.928 -14.025 6.803 1.00 84.29 ? 676 PRO A C 1 ATOM 4726 O O . PRO A 1 676 ? -5.134 -14.428 7.654 1.00 85.14 ? 676 PRO A O 1 ATOM 4727 C CB . PRO A 1 676 ? -4.794 -14.786 4.701 1.00 75.35 ? 676 PRO A CB 1 ATOM 4728 C CG . PRO A 1 676 ? -3.332 -14.697 4.991 1.00 60.67 ? 676 PRO A CG 1 ATOM 4729 C CD . PRO A 1 676 ? -3.023 -13.237 5.075 1.00 63.02 ? 676 PRO A CD 1 ATOM 4730 N N . GLN A 1 677 ? -7.239 -13.945 7.014 1.00 77.94 ? 677 GLN A N 1 ATOM 4731 C CA . GLN A 1 677 ? -7.818 -14.361 8.287 1.00 84.62 ? 677 GLN A CA 1 ATOM 4732 C C . GLN A 1 677 ? -8.391 -15.779 8.246 1.00 85.49 ? 677 GLN A C 1 ATOM 4733 O O . GLN A 1 677 ? -8.921 -16.267 9.245 1.00 89.21 ? 677 GLN A O 1 ATOM 4734 C CB . GLN A 1 677 ? -8.872 -13.358 8.777 1.00 89.73 ? 677 GLN A CB 1 ATOM 4735 C CG . GLN A 1 677 ? -10.261 -13.530 8.177 1.00 91.89 ? 677 GLN A CG 1 ATOM 4736 C CD . GLN A 1 677 ? -11.338 -12.850 9.008 1.00 95.42 ? 677 GLN A CD 1 ATOM 4737 O OE1 . GLN A 1 677 ? -11.047 -12.202 10.014 1.00 106.70 ? 677 GLN A OE1 1 ATOM 4738 N NE2 . GLN A 1 677 ? -12.591 -13.002 8.593 1.00 83.53 ? 677 GLN A NE2 1 ATOM 4739 N N . ARG A 1 678 ? -8.277 -16.440 7.097 1.00 79.47 ? 678 ARG A N 1 ATOM 4740 C CA . ARG A 1 678 ? -8.856 -17.771 6.940 1.00 78.80 ? 678 ARG A CA 1 ATOM 4741 C C . ARG A 1 678 ? -8.152 -18.611 5.873 1.00 73.13 ? 678 ARG A C 1 ATOM 4742 O O . ARG A 1 678 ? -7.484 -18.075 4.987 1.00 61.54 ? 678 ARG A O 1 ATOM 4743 C CB . ARG A 1 678 ? -10.349 -17.654 6.611 1.00 83.45 ? 678 ARG A CB 1 ATOM 4744 C CG . ARG A 1 678 ? -11.153 -18.908 6.906 1.00 85.74 ? 678 ARG A CG 1 ATOM 4745 C CD . ARG A 1 678 ? -11.632 -19.603 5.643 1.00 86.54 ? 678 ARG A CD 1 ATOM 4746 N NE . ARG A 1 678 ? -12.998 -19.215 5.313 1.00 88.54 ? 678 ARG A NE 1 ATOM 4747 C CZ . ARG A 1 678 ? -13.317 -18.224 4.488 1.00 81.75 ? 678 ARG A CZ 1 ATOM 4748 N NH1 . ARG A 1 678 ? -12.366 -17.518 3.892 1.00 67.06 ? 678 ARG A NH1 1 ATOM 4749 N NH2 . ARG A 1 678 ? -14.591 -17.943 4.254 1.00 91.51 ? 678 ARG A NH2 1 ATOM 4750 N N . GLY A 1 679 ? -8.299 -19.930 5.976 1.00 75.85 ? 679 GLY A N 1 ATOM 4751 C CA . GLY A 1 679 ? -7.877 -20.839 4.925 1.00 72.02 ? 679 GLY A CA 1 ATOM 4752 C C . GLY A 1 679 ? -6.508 -21.461 5.108 1.00 72.66 ? 679 GLY A C 1 ATOM 4753 O O . GLY A 1 679 ? -5.929 -21.415 6.193 1.00 80.85 ? 679 GLY A O 1 ATOM 4754 N N . LEU A 1 680 ? -5.997 -22.050 4.032 1.00 70.80 ? 680 LEU A N 1 ATOM 4755 C CA . LEU A 1 680 ? -4.650 -22.612 4.005 1.00 73.62 ? 680 LEU A CA 1 ATOM 4756 C C . LEU A 1 680 ? -3.752 -21.687 3.188 1.00 69.41 ? 680 LEU A C 1 ATOM 4757 O O . LEU A 1 680 ? -3.884 -21.603 1.967 1.00 71.92 ? 680 LEU A O 1 ATOM 4758 C CB . LEU A 1 680 ? -4.682 -24.010 3.384 1.00 73.10 ? 680 LEU A CB 1 ATOM 4759 C CG . LEU A 1 680 ? -3.371 -24.736 3.074 1.00 70.63 ? 680 LEU A CG 1 ATOM 4760 C CD1 . LEU A 1 680 ? -2.613 -25.064 4.347 1.00 87.07 ? 680 LEU A CD1 1 ATOM 4761 C CD2 . LEU A 1 680 ? -3.651 -25.999 2.275 1.00 59.04 ? 680 LEU A CD2 1 ATOM 4762 N N . VAL A 1 681 ? -2.831 -21.004 3.860 1.00 69.98 ? 681 VAL A N 1 ATOM 4763 C CA . VAL A 1 681 ? -2.084 -19.916 3.231 1.00 69.17 ? 681 VAL A CA 1 ATOM 4764 C C . VAL A 1 681 ? -0.709 -20.314 2.691 1.00 75.88 ? 681 VAL A C 1 ATOM 4765 O O . VAL A 1 681 ? 0.124 -20.867 3.411 1.00 82.59 ? 681 VAL A O 1 ATOM 4766 C CB . VAL A 1 681 ? -1.929 -18.717 4.192 1.00 69.46 ? 681 VAL A CB 1 ATOM 4767 C CG1 . VAL A 1 681 ? -1.241 -17.556 3.490 1.00 66.16 ? 681 VAL A CG1 1 ATOM 4768 C CG2 . VAL A 1 681 ? -3.287 -18.289 4.715 1.00 65.93 ? 681 VAL A CG2 1 ATOM 4769 N N . TYR A 1 682 ? -0.491 -20.026 1.412 1.00 72.30 ? 682 TYR A N 1 ATOM 4770 C CA . TYR A 1 682 ? 0.818 -20.168 0.791 1.00 73.27 ? 682 TYR A CA 1 ATOM 4771 C C . TYR A 1 682 ? 1.327 -18.781 0.421 1.00 74.90 ? 682 TYR A C 1 ATOM 4772 O O . TYR A 1 682 ? 0.792 -18.141 -0.485 1.00 72.58 ? 682 TYR A O 1 ATOM 4773 C CB . TYR A 1 682 ? 0.728 -21.024 -0.472 1.00 67.90 ? 682 TYR A CB 1 ATOM 4774 C CG . TYR A 1 682 ? 0.248 -22.440 -0.247 1.00 71.45 ? 682 TYR A CG 1 ATOM 4775 C CD1 . TYR A 1 682 ? -1.105 -22.728 -0.137 1.00 74.05 ? 682 TYR A CD1 1 ATOM 4776 C CD2 . TYR A 1 682 ? 1.149 -23.492 -0.161 1.00 76.03 ? 682 TYR A CD2 1 ATOM 4777 C CE1 . TYR A 1 682 ? -1.547 -24.021 0.060 1.00 76.97 ? 682 TYR A CE1 1 ATOM 4778 C CE2 . TYR A 1 682 ? 0.716 -24.790 0.034 1.00 76.92 ? 682 TYR A CE2 1 ATOM 4779 C CZ . TYR A 1 682 ? -0.633 -25.048 0.145 1.00 77.08 ? 682 TYR A CZ 1 ATOM 4780 O OH . TYR A 1 682 ? -1.068 -26.338 0.341 1.00 79.74 ? 682 TYR A OH 1 ATOM 4781 N N . SER A 1 683 ? 2.353 -18.313 1.123 1.00 82.54 ? 683 SER A N 1 ATOM 4782 C CA . SER A 1 683 ? 2.918 -16.998 0.842 1.00 82.30 ? 683 SER A CA 1 ATOM 4783 C C . SER A 1 683 ? 4.178 -17.125 -0.000 1.00 84.15 ? 683 SER A C 1 ATOM 4784 O O . SER A 1 683 ? 5.053 -17.941 0.291 1.00 88.46 ? 683 SER A O 1 ATOM 4785 C CB . SER A 1 683 ? 3.222 -16.244 2.138 1.00 82.44 ? 683 SER A CB 1 ATOM 4786 O OG . SER A 1 683 ? 3.644 -14.919 1.864 1.00 79.82 ? 683 SER A OG 1 ATOM 4787 N N . LEU A 1 684 ? 4.263 -16.313 -1.047 1.00 87.61 ? 684 LEU A N 1 ATOM 4788 C CA . LEU A 1 684 ? 5.409 -16.342 -1.944 1.00 97.27 ? 684 LEU A CA 1 ATOM 4789 C C . LEU A 1 684 ? 6.431 -15.306 -1.472 1.00 101.21 ? 684 LEU A C 1 ATOM 4790 O O . LEU A 1 684 ? 6.178 -14.103 -1.522 1.00 101.60 ? 684 LEU A O 1 ATOM 4791 C CB . LEU A 1 684 ? 4.957 -16.070 -3.383 1.00 98.09 ? 684 LEU A CB 1 ATOM 4792 C CG . LEU A 1 684 ? 3.639 -16.737 -3.812 1.00 90.09 ? 684 LEU A CG 1 ATOM 4793 C CD1 . LEU A 1 684 ? 3.257 -16.368 -5.241 1.00 76.46 ? 684 LEU A CD1 1 ATOM 4794 C CD2 . LEU A 1 684 ? 3.693 -18.251 -3.650 1.00 83.76 ? 684 LEU A CD2 1 ATOM 4795 N N . ALA A 1 685 ? 7.584 -15.784 -1.009 1.00 106.42 ? 685 ALA A N 1 ATOM 4796 C CA . ALA A 1 685 ? 8.561 -14.934 -0.326 1.00 115.97 ? 685 ALA A CA 1 ATOM 4797 C C . ALA A 1 685 ? 9.438 -14.124 -1.278 1.00 114.36 ? 685 ALA A C 1 ATOM 4798 O O . ALA A 1 685 ? 10.130 -13.194 -0.862 1.00 124.64 ? 685 ALA A O 1 ATOM 4799 C CB . ALA A 1 685 ? 9.426 -15.771 0.613 1.00 117.06 ? 685 ALA A CB 1 ATOM 4800 N N . ASP A 1 686 ? 9.401 -14.478 -2.557 1.00 103.52 ? 686 ASP A N 1 ATOM 4801 C CA . ASP A 1 686 ? 10.182 -13.785 -3.576 1.00 98.90 ? 686 ASP A CA 1 ATOM 4802 C C . ASP A 1 686 ? 9.615 -12.400 -3.892 1.00 97.17 ? 686 ASP A C 1 ATOM 4803 O O . ASP A 1 686 ? 10.195 -11.643 -4.670 1.00 89.55 ? 686 ASP A O 1 ATOM 4804 C CB . ASP A 1 686 ? 10.257 -14.635 -4.844 1.00 105.59 ? 686 ASP A CB 1 ATOM 4805 C CG . ASP A 1 686 ? 8.911 -15.212 -5.236 1.00 112.97 ? 686 ASP A CG 1 ATOM 4806 O OD1 . ASP A 1 686 ? 8.052 -15.376 -4.344 1.00 107.59 ? 686 ASP A OD1 1 ATOM 4807 O OD2 . ASP A 1 686 ? 8.712 -15.505 -6.434 1.00 105.53 ? 686 ASP A OD2 1 ATOM 4808 N N . VAL A 1 687 ? 8.487 -12.074 -3.269 1.00 97.49 ? 687 VAL A N 1 ATOM 4809 C CA . VAL A 1 687 ? 7.712 -10.885 -3.603 1.00 92.96 ? 687 VAL A CA 1 ATOM 4810 C C . VAL A 1 687 ? 7.913 -9.765 -2.579 1.00 84.80 ? 687 VAL A C 1 ATOM 4811 O O . VAL A 1 687 ? 8.177 -10.028 -1.406 1.00 85.15 ? 687 VAL A O 1 ATOM 4812 C CB . VAL A 1 687 ? 6.211 -11.228 -3.694 1.00 99.14 ? 687 VAL A CB 1 ATOM 4813 C CG1 . VAL A 1 687 ? 5.456 -10.150 -4.450 1.00 98.12 ? 687 VAL A CG1 1 ATOM 4814 C CG2 . VAL A 1 687 ? 6.020 -12.573 -4.373 1.00 97.35 ? 687 VAL A CG2 1 ATOM 4815 N N . ASP A 1 688 ? 7.795 -8.521 -3.041 1.00 75.78 ? 688 ASP A N 1 ATOM 4816 C CA . ASP A 1 688 ? 7.997 -7.326 -2.219 1.00 78.20 ? 688 ASP A CA 1 ATOM 4817 C C . ASP A 1 688 ? 7.136 -7.314 -0.952 1.00 85.70 ? 688 ASP A C 1 ATOM 4818 O O . ASP A 1 688 ? 6.017 -7.826 -0.941 1.00 92.56 ? 688 ASP A O 1 ATOM 4819 C CB . ASP A 1 688 ? 7.721 -6.074 -3.066 1.00 73.29 ? 688 ASP A CB 1 ATOM 4820 C CG . ASP A 1 688 ? 7.661 -4.798 -2.243 1.00 79.71 ? 688 ASP A CG 1 ATOM 4821 O OD1 . ASP A 1 688 ? 8.453 -4.655 -1.288 1.00 88.93 ? 688 ASP A OD1 1 ATOM 4822 O OD2 . ASP A 1 688 ? 6.817 -3.932 -2.557 1.00 79.77 ? 688 ASP A OD2 1 ATOM 4823 N N . VAL A 1 689 ? 7.686 -6.738 0.114 1.00 89.84 ? 689 VAL A N 1 ATOM 4824 C CA . VAL A 1 689 ? 7.035 -6.690 1.421 1.00 89.84 ? 689 VAL A CA 1 ATOM 4825 C C . VAL A 1 689 ? 5.686 -5.974 1.394 1.00 95.88 ? 689 VAL A C 1 ATOM 4826 O O . VAL A 1 689 ? 4.680 -6.515 1.853 1.00 101.09 ? 689 VAL A O 1 ATOM 4827 C CB . VAL A 1 689 ? 7.943 -6.003 2.468 1.00 98.18 ? 689 VAL A CB 1 ATOM 4828 C CG1 . VAL A 1 689 ? 7.186 -5.761 3.767 1.00 99.18 ? 689 VAL A CG1 1 ATOM 4829 C CG2 . VAL A 1 689 ? 9.192 -6.836 2.717 1.00 102.26 ? 689 VAL A CG2 1 ATOM 4830 N N . TYR A 1 690 ? 5.670 -4.759 0.852 1.00 99.84 ? 690 TYR A N 1 ATOM 4831 C CA . TYR A 1 690 ? 4.468 -3.929 0.876 1.00 108.25 ? 690 TYR A CA 1 ATOM 4832 C C . TYR A 1 690 ? 3.397 -4.383 -0.120 1.00 100.61 ? 690 TYR A C 1 ATOM 4833 O O . TYR A 1 690 ? 2.209 -4.128 0.078 1.00 101.56 ? 690 TYR A O 1 ATOM 4834 C CB . TYR A 1 690 ? 4.825 -2.459 0.641 1.00 117.31 ? 690 TYR A CB 1 ATOM 4835 C CG . TYR A 1 690 ? 3.962 -1.496 1.427 1.00 135.24 ? 690 TYR A CG 1 ATOM 4836 C CD1 . TYR A 1 690 ? 4.471 -0.809 2.521 1.00 142.42 ? 690 TYR A CD1 1 ATOM 4837 C CD2 . TYR A 1 690 ? 2.632 -1.286 1.084 1.00 128.35 ? 690 TYR A CD2 1 ATOM 4838 C CE1 . TYR A 1 690 ? 3.683 0.068 3.244 1.00 142.77 ? 690 TYR A CE1 1 ATOM 4839 C CE2 . TYR A 1 690 ? 1.837 -0.413 1.800 1.00 124.91 ? 690 TYR A CE2 1 ATOM 4840 C CZ . TYR A 1 690 ? 2.367 0.261 2.878 1.00 134.97 ? 690 TYR A CZ 1 ATOM 4841 O OH . TYR A 1 690 ? 1.576 1.132 3.593 1.00 123.11 ? 690 TYR A OH 1 ATOM 4842 N N . ASN A 1 691 ? 3.819 -5.055 -1.185 1.00 96.71 ? 691 ASN A N 1 ATOM 4843 C CA . ASN A 1 691 ? 2.891 -5.544 -2.199 1.00 91.74 ? 691 ASN A CA 1 ATOM 4844 C C . ASN A 1 691 ? 3.013 -7.056 -2.379 1.00 87.50 ? 691 ASN A C 1 ATOM 4845 O O . ASN A 1 691 ? 3.478 -7.522 -3.415 1.00 79.38 ? 691 ASN A O 1 ATOM 4846 C CB . ASN A 1 691 ? 3.160 -4.835 -3.528 1.00 93.72 ? 691 ASN A CB 1 ATOM 4847 C CG . ASN A 1 691 ? 2.017 -4.977 -4.512 1.00 97.67 ? 691 ASN A CG 1 ATOM 4848 O OD1 . ASN A 1 691 ? 0.869 -5.192 -4.124 1.00 101.11 ? 691 ASN A OD1 1 ATOM 4849 N ND2 . ASN A 1 691 ? 2.326 -4.850 -5.798 1.00 94.36 ? 691 ASN A ND2 1 ATOM 4850 N N . PRO A 1 692 ? 2.590 -7.833 -1.368 1.00 90.18 ? 692 PRO A N 1 ATOM 4851 C CA . PRO A 1 692 ? 2.849 -9.275 -1.402 1.00 88.95 ? 692 PRO A CA 1 ATOM 4852 C C . PRO A 1 692 ? 1.797 -10.057 -2.178 1.00 87.46 ? 692 PRO A C 1 ATOM 4853 O O . PRO A 1 692 ? 0.820 -9.481 -2.655 1.00 90.74 ? 692 PRO A O 1 ATOM 4854 C CB . PRO A 1 692 ? 2.783 -9.660 0.074 1.00 89.11 ? 692 PRO A CB 1 ATOM 4855 C CG . PRO A 1 692 ? 1.768 -8.723 0.640 1.00 87.88 ? 692 PRO A CG 1 ATOM 4856 C CD . PRO A 1 692 ? 1.871 -7.433 -0.145 1.00 89.92 ? 692 PRO A CD 1 ATOM 4857 N N . ILE A 1 693 ? 2.004 -11.365 -2.290 1.00 87.22 ? 693 ILE A N 1 ATOM 4858 C CA . ILE A 1 693 ? 1.046 -12.255 -2.934 1.00 89.21 ? 693 ILE A CA 1 ATOM 4859 C C . ILE A 1 693 ? 0.868 -13.511 -2.085 1.00 84.39 ? 693 ILE A C 1 ATOM 4860 O O . ILE A 1 693 ? 1.837 -14.208 -1.785 1.00 86.75 ? 693 ILE A O 1 ATOM 4861 C CB . ILE A 1 693 ? 1.500 -12.657 -4.357 1.00 81.32 ? 693 ILE A CB 1 ATOM 4862 C CG1 . ILE A 1 693 ? 1.523 -11.438 -5.282 1.00 73.35 ? 693 ILE A CG1 1 ATOM 4863 C CG2 . ILE A 1 693 ? 0.587 -13.730 -4.932 1.00 71.26 ? 693 ILE A CG2 1 ATOM 4864 C CD1 . ILE A 1 693 ? 1.991 -11.746 -6.689 1.00 76.42 ? 693 ILE A CD1 1 ATOM 4865 N N . SER A 1 694 ? -0.370 -13.793 -1.696 1.00 73.28 ? 694 SER A N 1 ATOM 4866 C CA . SER A 1 694 ? -0.662 -14.963 -0.879 1.00 71.38 ? 694 SER A CA 1 ATOM 4867 C C . SER A 1 694 ? -1.717 -15.817 -1.561 1.00 72.74 ? 694 SER A C 1 ATOM 4868 O O . SER A 1 694 ? -2.844 -15.363 -1.760 1.00 73.61 ? 694 SER A O 1 ATOM 4869 C CB . SER A 1 694 ? -1.176 -14.528 0.494 1.00 69.68 ? 694 SER A CB 1 ATOM 4870 O OG . SER A 1 694 ? -0.435 -13.429 0.993 1.00 80.68 ? 694 SER A OG 1 ATOM 4871 N N . VAL A 1 695 ? -1.376 -17.056 -1.909 1.00 71.25 ? 695 VAL A N 1 ATOM 4872 C CA . VAL A 1 695 ? -2.378 -17.930 -2.504 1.00 64.15 ? 695 VAL A CA 1 ATOM 4873 C C . VAL A 1 695 ? -3.019 -18.736 -1.383 1.00 63.04 ? 695 VAL A C 1 ATOM 4874 O O . VAL A 1 695 ? -2.426 -19.678 -0.860 1.00 69.46 ? 695 VAL A O 1 ATOM 4875 C CB . VAL A 1 695 ? -1.736 -18.909 -3.511 1.00 53.68 ? 695 VAL A CB 1 ATOM 4876 C CG1 . VAL A 1 695 ? -2.798 -19.754 -4.199 1.00 55.58 ? 695 VAL A CG1 1 ATOM 4877 C CG2 . VAL A 1 695 ? -0.906 -18.157 -4.538 1.00 52.84 ? 695 VAL A CG2 1 ATOM 4878 N N . VAL A 1 696 ? -4.239 -18.354 -1.022 1.00 51.36 ? 696 VAL A N 1 ATOM 4879 C CA . VAL A 1 696 ? -5.025 -19.070 -0.025 1.00 49.38 ? 696 VAL A CA 1 ATOM 4880 C C . VAL A 1 696 ? -5.794 -20.220 -0.663 1.00 56.06 ? 696 VAL A C 1 ATOM 4881 O O . VAL A 1 696 ? -6.073 -20.187 -1.859 1.00 64.34 ? 696 VAL A O 1 ATOM 4882 C CB . VAL A 1 696 ? -5.987 -18.127 0.711 1.00 51.03 ? 696 VAL A CB 1 ATOM 4883 C CG1 . VAL A 1 696 ? -6.281 -18.656 2.102 1.00 57.75 ? 696 VAL A CG1 1 ATOM 4884 C CG2 . VAL A 1 696 ? -5.387 -16.734 0.794 1.00 45.01 ? 696 VAL A CG2 1 ATOM 4885 N N . TYR A 1 697 ? -6.135 -21.235 0.122 1.00 57.79 ? 697 TYR A N 1 ATOM 4886 C CA . TYR A 1 697 ? -7.040 -22.265 -0.361 1.00 60.17 ? 697 TYR A CA 1 ATOM 4887 C C . TYR A 1 697 ? -8.186 -22.376 0.638 1.00 65.19 ? 697 TYR A C 1 ATOM 4888 O O . TYR A 1 697 ? -8.020 -22.889 1.745 1.00 65.32 ? 697 TYR A O 1 ATOM 4889 C CB . TYR A 1 697 ? -6.273 -23.583 -0.480 1.00 60.00 ? 697 TYR A CB 1 ATOM 4890 C CG . TYR A 1 697 ? -7.055 -24.775 -0.984 1.00 65.46 ? 697 TYR A CG 1 ATOM 4891 C CD1 . TYR A 1 697 ? -7.342 -25.839 -0.141 1.00 73.96 ? 697 TYR A CD1 1 ATOM 4892 C CD2 . TYR A 1 697 ? -7.477 -24.853 -2.303 1.00 68.21 ? 697 TYR A CD2 1 ATOM 4893 C CE1 . TYR A 1 697 ? -8.040 -26.941 -0.590 1.00 76.89 ? 697 TYR A CE1 1 ATOM 4894 C CE2 . TYR A 1 697 ? -8.179 -25.956 -2.764 1.00 75.14 ? 697 TYR A CE2 1 ATOM 4895 C CZ . TYR A 1 697 ? -8.455 -26.996 -1.901 1.00 77.68 ? 697 TYR A CZ 1 ATOM 4896 O OH . TYR A 1 697 ? -9.150 -28.099 -2.343 1.00 74.84 ? 697 TYR A OH 1 ATOM 4897 N N . LEU A 1 698 ? -9.349 -21.881 0.225 1.00 69.95 ? 698 LEU A N 1 ATOM 4898 C CA . LEU A 1 698 ? -10.540 -21.828 1.072 1.00 70.29 ? 698 LEU A CA 1 ATOM 4899 C C . LEU A 1 698 ? -11.374 -23.109 1.068 1.00 73.47 ? 698 LEU A C 1 ATOM 4900 O O . LEU A 1 698 ? -11.336 -23.882 0.112 1.00 74.06 ? 698 LEU A O 1 ATOM 4901 C CB . LEU A 1 698 ? -11.397 -20.604 0.724 1.00 70.90 ? 698 LEU A CB 1 ATOM 4902 C CG . LEU A 1 698 ? -10.665 -19.260 0.819 1.00 66.90 ? 698 LEU A CG 1 ATOM 4903 C CD1 . LEU A 1 698 ? -11.611 -18.093 0.597 1.00 72.03 ? 698 LEU A CD1 1 ATOM 4904 C CD2 . LEU A 1 698 ? -9.966 -19.125 2.158 1.00 73.47 ? 698 LEU A CD2 1 ATOM 4905 N N . SER A 1 699 ? -12.123 -23.327 2.144 1.00 78.94 ? 699 SER A N 1 ATOM 4906 C CA . SER A 1 699 ? -13.071 -24.435 2.203 1.00 92.44 ? 699 SER A CA 1 ATOM 4907 C C . SER A 1 699 ? -14.404 -23.968 2.776 1.00 98.16 ? 699 SER A C 1 ATOM 4908 O O . SER A 1 699 ? -14.447 -23.050 3.595 1.00 101.48 ? 699 SER A O 1 ATOM 4909 C CB . SER A 1 699 ? -12.510 -25.587 3.035 1.00 97.21 ? 699 SER A CB 1 ATOM 4910 O OG . SER A 1 699 ? -11.253 -26.012 2.541 1.00 99.62 ? 699 SER A OG 1 ATOM 4911 N N . LYS A 1 700 ? -15.489 -24.597 2.332 1.00 99.42 ? 700 LYS A N 1 ATOM 4912 C CA . LYS A 1 700 ? -16.833 -24.235 2.773 1.00 102.44 ? 700 LYS A CA 1 ATOM 4913 C C . LYS A 1 700 ? -17.001 -24.347 4.288 1.00 108.99 ? 700 LYS A C 1 ATOM 4914 O O . LYS A 1 700 ? -17.179 -23.344 4.978 1.00 102.50 ? 700 LYS A O 1 ATOM 4915 C CB . LYS A 1 700 ? -17.886 -25.081 2.048 1.00 103.28 ? 700 LYS A CB 1 ATOM 4916 C CG . LYS A 1 700 ? -19.325 -24.688 2.351 1.00 96.12 ? 700 LYS A CG 1 ATOM 4917 C CD . LYS A 1 700 ? -20.180 -24.712 1.092 1.00 97.22 ? 700 LYS A CD 1 ATOM 4918 C CE . LYS A 1 700 ? -21.559 -24.116 1.342 1.00 99.22 ? 700 LYS A CE 1 ATOM 4919 N NZ . LYS A 1 700 ? -22.359 -23.994 0.088 1.00 80.47 ? 700 LYS A NZ 1 ATOM 4920 N N . ASP A 1 701 ? -16.931 -25.570 4.802 1.00 119.69 ? 701 ASP A N 1 ATOM 4921 C CA . ASP A 1 701 ? -17.135 -25.802 6.227 1.00 121.37 ? 701 ASP A CA 1 ATOM 4922 C C . ASP A 1 701 ? -15.868 -25.596 7.059 1.00 119.68 ? 701 ASP A C 1 ATOM 4923 O O . ASP A 1 701 ? -15.934 -25.564 8.288 1.00 118.68 ? 701 ASP A O 1 ATOM 4924 C CB . ASP A 1 701 ? -17.714 -27.199 6.475 1.00 122.73 ? 701 ASP A CB 1 ATOM 4925 C CG . ASP A 1 701 ? -16.812 -28.306 5.964 1.00 125.97 ? 701 ASP A CG 1 ATOM 4926 O OD1 . ASP A 1 701 ? -15.840 -28.657 6.666 1.00 127.53 ? 701 ASP A OD1 1 ATOM 4927 O OD2 . ASP A 1 701 ? -17.082 -28.835 4.865 1.00 125.68 ? 701 ASP A OD2 1 ATOM 4928 N N . THR A 1 702 ? -14.721 -25.451 6.400 1.00 117.76 ? 702 THR A N 1 ATOM 4929 C CA . THR A 1 702 ? -13.469 -25.268 7.129 1.00 121.37 ? 702 THR A CA 1 ATOM 4930 C C . THR A 1 702 ? -13.032 -23.805 7.121 1.00 115.43 ? 702 THR A C 1 ATOM 4931 O O . THR A 1 702 ? -12.545 -23.288 6.113 1.00 106.68 ? 702 THR A O 1 ATOM 4932 C CB . THR A 1 702 ? -12.343 -26.139 6.531 1.00 120.49 ? 702 THR A CB 1 ATOM 4933 O OG1 . THR A 1 702 ? -12.693 -27.525 6.641 1.00 125.51 ? 702 THR A OG1 1 ATOM 4934 C CG2 . THR A 1 702 ? -11.029 -25.895 7.252 1.00 112.34 ? 702 THR A CG2 1 ATOM 4935 N N . CYS A 1 703 ? -13.220 -23.147 8.260 1.00 117.15 ? 703 CYS A N 1 ATOM 4936 C CA . CYS A 1 703 ? -12.820 -21.754 8.449 1.00 114.31 ? 703 CYS A CA 1 ATOM 4937 C C . CYS A 1 703 ? -11.521 -21.551 9.237 1.00 110.49 ? 703 CYS A C 1 ATOM 4938 O O . CYS A 1 703 ? -11.151 -20.420 9.552 1.00 104.05 ? 703 CYS A O 1 ATOM 4939 C CB . CYS A 1 703 ? -13.970 -20.934 9.039 1.00 119.57 ? 703 CYS A CB 1 ATOM 4940 S SG . CYS A 1 703 ? -15.368 -20.755 7.899 1.00 118.45 ? 703 CYS A SG 1 ATOM 4941 N N . VAL A 1 704 ? -10.856 -22.644 9.594 1.00 113.41 ? 704 VAL A N 1 ATOM 4942 C CA . VAL A 1 704 ? -9.621 -22.555 10.370 1.00 108.23 ? 704 VAL A CA 1 ATOM 4943 C C . VAL A 1 704 ? -8.452 -22.037 9.524 1.00 104.51 ? 704 VAL A C 1 ATOM 4944 O O . VAL A 1 704 ? -8.364 -22.314 8.327 1.00 105.73 ? 704 VAL A O 1 ATOM 4945 C CB . VAL A 1 704 ? -9.262 -23.912 11.031 1.00 107.08 ? 704 VAL A CB 1 ATOM 4946 C CG1 . VAL A 1 704 ? -8.895 -24.951 9.982 1.00 107.05 ? 704 VAL A CG1 1 ATOM 4947 C CG2 . VAL A 1 704 ? -8.135 -23.742 12.040 1.00 107.54 ? 704 VAL A CG2 1 ATOM 4948 N N . SER A 1 705 ? -7.569 -21.263 10.151 1.00 100.27 ? 705 SER A N 1 ATOM 4949 C CA . SER A 1 705 ? -6.380 -20.751 9.478 1.00 92.08 ? 705 SER A CA 1 ATOM 4950 C C . SER A 1 705 ? -5.163 -21.622 9.767 1.00 88.80 ? 705 SER A C 1 ATOM 4951 O O . SER A 1 705 ? -4.994 -22.121 10.878 1.00 93.28 ? 705 SER A O 1 ATOM 4952 C CB . SER A 1 705 ? -6.097 -19.310 9.905 1.00 87.98 ? 705 SER A CB 1 ATOM 4953 O OG . SER A 1 705 ? -4.840 -18.873 9.417 1.00 69.39 ? 705 SER A OG 1 ATOM 4954 N N . GLU A 1 706 ? -4.322 -21.800 8.753 1.00 84.63 ? 706 GLU A N 1 ATOM 4955 C CA . GLU A 1 706 ? -3.070 -22.532 8.899 1.00 89.76 ? 706 GLU A CA 1 ATOM 4956 C C . GLU A 1 706 ? -2.132 -22.163 7.760 1.00 81.88 ? 706 GLU A C 1 ATOM 4957 O O . GLU A 1 706 ? -2.435 -21.278 6.962 1.00 83.05 ? 706 GLU A O 1 ATOM 4958 C CB . GLU A 1 706 ? -3.314 -24.043 8.908 1.00 95.37 ? 706 GLU A CB 1 ATOM 4959 C CG . GLU A 1 706 ? -4.006 -24.573 7.663 1.00 93.50 ? 706 GLU A CG 1 ATOM 4960 C CD . GLU A 1 706 ? -3.966 -26.087 7.572 1.00 99.81 ? 706 GLU A CD 1 ATOM 4961 O OE1 . GLU A 1 706 ? -5.031 -26.723 7.727 1.00 109.56 ? 706 GLU A OE1 1 ATOM 4962 O OE2 . GLU A 1 706 ? -2.871 -26.642 7.339 1.00 89.53 ? 706 GLU A OE2 1 ATOM 4963 N N . HIS A 1 707 ? -0.992 -22.841 7.688 1.00 80.51 ? 707 HIS A N 1 ATOM 4964 C CA . HIS A 1 707 ? -0.038 -22.603 6.611 1.00 87.23 ? 707 HIS A CA 1 ATOM 4965 C C . HIS A 1 707 ? 0.451 -23.908 5.992 1.00 86.74 ? 707 HIS A C 1 ATOM 4966 O O . HIS A 1 707 ? 0.652 -24.903 6.689 1.00 87.53 ? 707 HIS A O 1 ATOM 4967 C CB . HIS A 1 707 ? 1.143 -21.762 7.103 1.00 95.48 ? 707 HIS A CB 1 ATOM 4968 C CG . HIS A 1 707 ? 0.810 -20.315 7.301 1.00 102.06 ? 707 HIS A CG 1 ATOM 4969 N ND1 . HIS A 1 707 ? -0.027 -19.873 8.303 1.00 105.42 ? 707 HIS A ND1 1 ATOM 4970 C CD2 . HIS A 1 707 ? 1.197 -19.211 6.620 1.00 92.36 ? 707 HIS A CD2 1 ATOM 4971 C CE1 . HIS A 1 707 ? -0.138 -18.559 8.233 1.00 96.03 ? 707 HIS A CE1 1 ATOM 4972 N NE2 . HIS A 1 707 ? 0.595 -18.132 7.221 1.00 97.14 ? 707 HIS A NE2 1 ATOM 4973 N N . GLY A 1 708 ? 0.632 -23.896 4.677 1.00 85.66 ? 708 GLY A N 1 ATOM 4974 C CA . GLY A 1 708 ? 1.067 -25.077 3.958 1.00 78.38 ? 708 GLY A CA 1 ATOM 4975 C C . GLY A 1 708 ? 2.536 -25.013 3.599 1.00 79.51 ? 708 GLY A C 1 ATOM 4976 O O . GLY A 1 708 ? 3.258 -24.127 4.052 1.00 85.04 ? 708 GLY A O 1 ATOM 4977 N N . VAL A 1 709 ? 2.977 -25.960 2.779 1.00 77.58 ? 709 VAL A N 1 ATOM 4978 C CA . VAL A 1 709 ? 4.367 -26.024 2.356 1.00 69.75 ? 709 VAL A CA 1 ATOM 4979 C C . VAL A 1 709 ? 4.464 -25.950 0.839 1.00 67.52 ? 709 VAL A C 1 ATOM 4980 O O . VAL A 1 709 ? 3.933 -26.813 0.141 1.00 73.47 ? 709 VAL A O 1 ATOM 4981 C CB . VAL A 1 709 ? 5.024 -27.340 2.821 1.00 72.09 ? 709 VAL A CB 1 ATOM 4982 C CG1 . VAL A 1 709 ? 6.449 -27.440 2.299 1.00 79.36 ? 709 VAL A CG1 1 ATOM 4983 C CG2 . VAL A 1 709 ? 4.992 -27.446 4.339 1.00 81.86 ? 709 VAL A CG2 1 ATOM 4984 N N . ILE A 1 710 ? 5.136 -24.926 0.323 1.00 62.29 ? 710 ILE A N 1 ATOM 4985 C CA . ILE A 1 710 ? 5.379 -24.872 -1.110 1.00 64.85 ? 710 ILE A CA 1 ATOM 4986 C C . ILE A 1 710 ? 6.367 -25.981 -1.432 1.00 70.93 ? 710 ILE A C 1 ATOM 4987 O O . ILE A 1 710 ? 7.468 -26.018 -0.885 1.00 81.08 ? 710 ILE A O 1 ATOM 4988 C CB . ILE A 1 710 ? 5.967 -23.516 -1.552 1.00 67.08 ? 710 ILE A CB 1 ATOM 4989 C CG1 . ILE A 1 710 ? 4.898 -22.423 -1.503 1.00 73.85 ? 710 ILE A CG1 1 ATOM 4990 C CG2 . ILE A 1 710 ? 6.538 -23.614 -2.957 1.00 62.68 ? 710 ILE A CG2 1 ATOM 4991 C CD1 . ILE A 1 710 ? 5.367 -21.083 -2.037 1.00 72.77 ? 710 ILE A CD1 1 ATOM 4992 N N . GLU A 1 711 ? 5.969 -26.889 -2.315 1.00 70.48 ? 711 GLU A N 1 ATOM 4993 C CA . GLU A 1 711 ? 6.819 -28.014 -2.668 1.00 75.92 ? 711 GLU A CA 1 ATOM 4994 C C . GLU A 1 711 ? 7.439 -27.756 -4.030 1.00 74.97 ? 711 GLU A C 1 ATOM 4995 O O . GLU A 1 711 ? 7.196 -26.716 -4.642 1.00 74.48 ? 711 GLU A O 1 ATOM 4996 C CB . GLU A 1 711 ? 6.016 -29.319 -2.678 1.00 74.64 ? 711 GLU A CB 1 ATOM 4997 C CG . GLU A 1 711 ? 6.794 -30.539 -2.198 1.00 83.43 ? 711 GLU A CG 1 ATOM 4998 C CD . GLU A 1 711 ? 7.129 -30.474 -0.719 1.00 92.74 ? 711 GLU A CD 1 ATOM 4999 O OE1 . GLU A 1 711 ? 8.193 -30.997 -0.324 1.00 98.24 ? 711 GLU A OE1 1 ATOM 5000 O OE2 . GLU A 1 711 ? 6.326 -29.905 0.050 1.00 85.99 ? 711 GLU A OE2 1 ATOM 5001 N N . THR A 1 712 ? 8.250 -28.695 -4.498 1.00 77.59 ? 712 THR A N 1 ATOM 5002 C CA . THR A 1 712 ? 8.872 -28.572 -5.808 1.00 83.87 ? 712 THR A CA 1 ATOM 5003 C C . THR A 1 712 ? 8.834 -29.901 -6.551 1.00 89.28 ? 712 THR A C 1 ATOM 5004 O O . THR A 1 712 ? 9.237 -30.935 -6.017 1.00 92.07 ? 712 THR A O 1 ATOM 5005 C CB . THR A 1 712 ? 10.337 -28.079 -5.711 1.00 92.00 ? 712 THR A CB 1 ATOM 5006 O OG1 . THR A 1 712 ? 11.018 -28.781 -4.664 1.00 99.64 ? 712 THR A OG1 1 ATOM 5007 C CG2 . THR A 1 712 ? 10.387 -26.582 -5.424 1.00 87.38 ? 712 THR A CG2 1 ATOM 5008 N N . VAL A 1 713 ? 8.324 -29.871 -7.778 1.00 92.10 ? 713 VAL A N 1 ATOM 5009 C CA . VAL A 1 713 ? 8.399 -31.023 -8.668 1.00 93.62 ? 713 VAL A CA 1 ATOM 5010 C C . VAL A 1 713 ? 9.011 -30.580 -9.991 1.00 91.50 ? 713 VAL A C 1 ATOM 5011 O O . VAL A 1 713 ? 9.315 -29.402 -10.178 1.00 83.26 ? 713 VAL A O 1 ATOM 5012 C CB . VAL A 1 713 ? 7.014 -31.653 -8.928 1.00 90.37 ? 713 VAL A CB 1 ATOM 5013 C CG1 . VAL A 1 713 ? 6.344 -32.043 -7.616 1.00 84.25 ? 713 VAL A CG1 1 ATOM 5014 C CG2 . VAL A 1 713 ? 6.134 -30.702 -9.725 1.00 93.41 ? 713 VAL A CG2 1 ATOM 5015 N N . ALA A 1 714 ? 9.189 -31.522 -10.909 1.00 96.55 ? 714 ALA A N 1 ATOM 5016 C CA . ALA A 1 714 ? 9.727 -31.192 -12.221 1.00 108.71 ? 714 ALA A CA 1 ATOM 5017 C C . ALA A 1 714 ? 8.778 -31.658 -13.312 1.00 110.24 ? 714 ALA A C 1 ATOM 5018 O O . ALA A 1 714 ? 7.726 -32.229 -13.029 1.00 102.57 ? 714 ALA A O 1 ATOM 5019 C CB . ALA A 1 714 ? 11.103 -31.812 -12.407 1.00 108.76 ? 714 ALA A CB 1 ATOM 5020 N N . LEU A 1 715 ? 9.152 -31.408 -14.560 1.00 114.92 ? 715 LEU A N 1 ATOM 5021 C CA . LEU A 1 715 ? 8.335 -31.814 -15.695 1.00 126.21 ? 715 LEU A CA 1 ATOM 5022 C C . LEU A 1 715 ? 8.939 -33.012 -16.417 1.00 133.93 ? 715 LEU A C 1 ATOM 5023 O O . LEU A 1 715 ? 10.112 -32.985 -16.792 1.00 131.81 ? 715 LEU A O 1 ATOM 5024 C CB . LEU A 1 715 ? 8.142 -30.643 -16.659 1.00 124.92 ? 715 LEU A CB 1 ATOM 5025 C CG . LEU A 1 715 ? 6.998 -29.696 -16.297 1.00 115.84 ? 715 LEU A CG 1 ATOM 5026 C CD1 . LEU A 1 715 ? 7.419 -28.247 -16.475 1.00 112.53 ? 715 LEU A CD1 1 ATOM 5027 C CD2 . LEU A 1 715 ? 5.771 -30.016 -17.138 1.00 95.26 ? 715 LEU A CD2 1 ATOM 5028 N N . PRO A 1 716 ? 8.141 -34.077 -16.596 1.00 138.44 ? 716 PRO A N 1 ATOM 5029 C CA . PRO A 1 716 ? 8.597 -35.242 -17.357 1.00 146.45 ? 716 PRO A CA 1 ATOM 5030 C C . PRO A 1 716 ? 8.807 -34.844 -18.809 1.00 155.03 ? 716 PRO A C 1 ATOM 5031 O O . PRO A 1 716 ? 8.202 -33.867 -19.253 1.00 150.03 ? 716 PRO A O 1 ATOM 5032 C CB . PRO A 1 716 ? 7.419 -36.215 -17.243 1.00 130.44 ? 716 PRO A CB 1 ATOM 5033 C CG . PRO A 1 716 ? 6.232 -35.342 -17.028 1.00 123.15 ? 716 PRO A CG 1 ATOM 5034 C CD . PRO A 1 716 ? 6.732 -34.203 -16.185 1.00 127.69 ? 716 PRO A CD 1 ATOM 5035 N N . HIS A 1 717 ? 9.660 -35.569 -19.526 1.00 161.88 ? 717 HIS A N 1 ATOM 5036 C CA . HIS A 1 717 ? 9.878 -35.303 -20.941 1.00 165.26 ? 717 HIS A CA 1 ATOM 5037 C C . HIS A 1 717 ? 8.539 -35.402 -21.666 1.00 171.01 ? 717 HIS A C 1 ATOM 5038 O O . HIS A 1 717 ? 7.782 -36.346 -21.439 1.00 170.94 ? 717 HIS A O 1 ATOM 5039 C CB . HIS A 1 717 ? 10.885 -36.296 -21.524 1.00 167.27 ? 717 HIS A CB 1 ATOM 5040 C CG . HIS A 1 717 ? 11.324 -35.968 -22.918 1.00 175.27 ? 717 HIS A CG 1 ATOM 5041 N ND1 . HIS A 1 717 ? 10.626 -36.376 -24.034 1.00 175.60 ? 717 HIS A ND1 1 ATOM 5042 C CD2 . HIS A 1 717 ? 12.392 -35.272 -23.376 1.00 175.55 ? 717 HIS A CD2 1 ATOM 5043 C CE1 . HIS A 1 717 ? 11.244 -35.945 -25.119 1.00 173.43 ? 717 HIS A CE1 1 ATOM 5044 N NE2 . HIS A 1 717 ? 12.318 -35.272 -24.747 1.00 173.16 ? 717 HIS A NE2 1 ATOM 5045 N N . PRO A 1 718 ? 8.237 -34.413 -22.522 1.00 172.59 ? 718 PRO A N 1 ATOM 5046 C CA . PRO A 1 718 ? 6.937 -34.293 -23.196 1.00 166.54 ? 718 PRO A CA 1 ATOM 5047 C C . PRO A 1 718 ? 6.491 -35.572 -23.903 1.00 168.27 ? 718 PRO A C 1 ATOM 5048 O O . PRO A 1 718 ? 5.317 -35.938 -23.824 1.00 163.56 ? 718 PRO A O 1 ATOM 5049 C CB . PRO A 1 718 ? 7.170 -33.169 -24.219 1.00 163.23 ? 718 PRO A CB 1 ATOM 5050 C CG . PRO A 1 718 ? 8.662 -33.007 -24.304 1.00 166.88 ? 718 PRO A CG 1 ATOM 5051 C CD . PRO A 1 718 ? 9.166 -33.353 -22.945 1.00 168.79 ? 718 PRO A CD 1 ATOM 5052 N N . ASP A 1 719 ? 7.418 -36.238 -24.582 1.00 173.26 ? 719 ASP A N 1 ATOM 5053 C CA . ASP A 1 719 ? 7.100 -37.460 -25.315 1.00 174.15 ? 719 ASP A CA 1 ATOM 5054 C C . ASP A 1 719 ? 7.409 -38.738 -24.529 1.00 175.44 ? 719 ASP A C 1 ATOM 5055 O O . ASP A 1 719 ? 7.219 -39.843 -25.037 1.00 176.65 ? 719 ASP A O 1 ATOM 5056 C CB . ASP A 1 719 ? 7.816 -37.475 -26.668 1.00 173.22 ? 719 ASP A CB 1 ATOM 5057 C CG . ASP A 1 719 ? 7.334 -36.374 -27.594 1.00 166.69 ? 719 ASP A CG 1 ATOM 5058 O OD1 . ASP A 1 719 ? 6.126 -36.056 -27.567 1.00 162.11 ? 719 ASP A OD1 1 ATOM 5059 O OD2 . ASP A 1 719 ? 8.165 -35.824 -28.347 1.00 161.22 ? 719 ASP A OD2 1 ATOM 5060 N N . ASN A 1 720 ? 7.883 -38.586 -23.296 1.00 176.83 ? 720 ASN A N 1 ATOM 5061 C CA . ASN A 1 720 ? 8.165 -39.737 -22.442 1.00 177.19 ? 720 ASN A CA 1 ATOM 5062 C C . ASN A 1 720 ? 6.863 -40.337 -21.930 1.00 177.50 ? 720 ASN A C 1 ATOM 5063 O O . ASN A 1 720 ? 6.489 -41.450 -22.304 1.00 175.08 ? 720 ASN A O 1 ATOM 5064 C CB . ASN A 1 720 ? 9.058 -39.327 -21.265 1.00 173.04 ? 720 ASN A CB 1 ATOM 5065 C CG . ASN A 1 720 ? 9.605 -40.518 -20.487 1.00 171.05 ? 720 ASN A CG 1 ATOM 5066 O OD1 . ASN A 1 720 ? 8.930 -41.532 -20.310 1.00 176.65 ? 720 ASN A OD1 1 ATOM 5067 N ND2 . ASN A 1 720 ? 10.840 -40.391 -20.012 1.00 160.93 ? 720 ASN A ND2 1 ATOM 5068 N N . LEU A 1 721 ? 6.173 -39.590 -21.076 1.00 172.68 ? 721 LEU A N 1 ATOM 5069 C CA . LEU A 1 721 ? 4.894 -40.035 -20.545 1.00 162.34 ? 721 LEU A CA 1 ATOM 5070 C C . LEU A 1 721 ? 3.751 -39.510 -21.404 1.00 154.17 ? 721 LEU A C 1 ATOM 5071 O O . LEU A 1 721 ? 3.493 -38.307 -21.454 1.00 151.77 ? 721 LEU A O 1 ATOM 5072 C CB . LEU A 1 721 ? 4.727 -39.586 -19.090 1.00 160.43 ? 721 LEU A CB 1 ATOM 5073 C CG . LEU A 1 721 ? 5.398 -40.457 -18.025 1.00 159.63 ? 721 LEU A CG 1 ATOM 5074 C CD1 . LEU A 1 721 ? 5.520 -39.711 -16.705 1.00 144.06 ? 721 LEU A CD1 1 ATOM 5075 C CD2 . LEU A 1 721 ? 4.619 -41.750 -17.834 1.00 169.27 ? 721 LEU A CD2 1 ATOM 5076 N N . LYS A 1 722 ? 3.069 -40.431 -22.078 1.00 151.60 ? 722 LYS A N 1 ATOM 5077 C CA . LYS A 1 722 ? 1.908 -40.104 -22.894 1.00 149.74 ? 722 LYS A CA 1 ATOM 5078 C C . LYS A 1 722 ? 0.682 -40.094 -21.988 1.00 155.91 ? 722 LYS A C 1 ATOM 5079 O O . LYS A 1 722 ? -0.453 -39.977 -22.446 1.00 154.31 ? 722 LYS A O 1 ATOM 5080 C CB . LYS A 1 722 ? 1.746 -41.114 -24.034 1.00 137.62 ? 722 LYS A CB 1 ATOM 5081 C CG . LYS A 1 722 ? 0.991 -40.578 -25.245 1.00 125.72 ? 722 LYS A CG 1 ATOM 5082 C CD . LYS A 1 722 ? 1.757 -40.810 -26.545 1.00 118.27 ? 722 LYS A CD 1 ATOM 5083 C CE . LYS A 1 722 ? 1.485 -42.186 -27.141 1.00 112.67 ? 722 LYS A CE 1 ATOM 5084 N NZ . LYS A 1 722 ? 2.080 -43.302 -26.354 1.00 108.96 ? 722 LYS A NZ 1 ATOM 5085 N N . GLU A 1 723 ? 0.936 -40.267 -20.695 1.00 156.55 ? 723 GLU A N 1 ATOM 5086 C CA . GLU A 1 723 ? -0.081 -40.176 -19.658 1.00 154.14 ? 723 GLU A CA 1 ATOM 5087 C C . GLU A 1 723 ? -0.035 -38.786 -19.024 1.00 148.19 ? 723 GLU A C 1 ATOM 5088 O O . GLU A 1 723 ? 1.044 -38.225 -18.833 1.00 147.80 ? 723 GLU A O 1 ATOM 5089 C CB . GLU A 1 723 ? 0.185 -41.249 -18.604 1.00 157.87 ? 723 GLU A CB 1 ATOM 5090 C CG . GLU A 1 723 ? -0.719 -41.205 -17.390 1.00 158.22 ? 723 GLU A CG 1 ATOM 5091 C CD . GLU A 1 723 ? -0.342 -42.256 -16.365 1.00 159.71 ? 723 GLU A CD 1 ATOM 5092 O OE1 . GLU A 1 723 ? 0.595 -43.037 -16.635 1.00 153.30 ? 723 GLU A OE1 1 ATOM 5093 O OE2 . GLU A 1 723 ? -0.978 -42.301 -15.292 1.00 164.75 ? 723 GLU A OE2 1 ATOM 5094 N N . CYS A 1 724 ? -1.201 -38.230 -18.703 1.00 138.50 ? 724 CYS A N 1 ATOM 5095 C CA . CYS A 1 724 ? -1.268 -36.884 -18.138 1.00 132.55 ? 724 CYS A CA 1 ATOM 5096 C C . CYS A 1 724 ? -1.760 -36.873 -16.693 1.00 135.11 ? 724 CYS A C 1 ATOM 5097 O O . CYS A 1 724 ? -2.944 -37.094 -16.434 1.00 141.47 ? 724 CYS A O 1 ATOM 5098 C CB . CYS A 1 724 ? -2.194 -36.010 -18.990 1.00 129.43 ? 724 CYS A CB 1 ATOM 5099 S SG . CYS A 1 724 ? -2.684 -34.443 -18.227 1.00 128.16 ? 724 CYS A SG 1 ATOM 5100 N N . LEU A 1 725 ? -0.850 -36.624 -15.754 1.00 131.31 ? 725 LEU A N 1 ATOM 5101 C CA . LEU A 1 725 ? -1.232 -36.391 -14.363 1.00 134.40 ? 725 LEU A CA 1 ATOM 5102 C C . LEU A 1 725 ? -1.338 -34.895 -14.043 1.00 124.50 ? 725 LEU A C 1 ATOM 5103 O O . LEU A 1 725 ? -1.866 -34.507 -13.000 1.00 119.14 ? 725 LEU A O 1 ATOM 5104 C CB . LEU A 1 725 ? -0.243 -37.075 -13.413 1.00 135.26 ? 725 LEU A CB 1 ATOM 5105 C CG . LEU A 1 725 ? -0.649 -37.195 -11.940 1.00 121.00 ? 725 LEU A CG 1 ATOM 5106 C CD1 . LEU A 1 725 ? -1.947 -37.977 -11.802 1.00 118.42 ? 725 LEU A CD1 1 ATOM 5107 C CD2 . LEU A 1 725 ? 0.458 -37.834 -11.112 1.00 107.28 ? 725 LEU A CD2 1 ATOM 5108 N N . TYR A 1 726 ? -0.857 -34.060 -14.959 1.00 117.49 ? 726 TYR A N 1 ATOM 5109 C CA . TYR A 1 726 ? -0.772 -32.620 -14.718 1.00 112.61 ? 726 TYR A CA 1 ATOM 5110 C C . TYR A 1 726 ? -2.103 -31.895 -14.895 1.00 115.41 ? 726 TYR A C 1 ATOM 5111 O O . TYR A 1 726 ? -2.412 -30.960 -14.153 1.00 108.85 ? 726 TYR A O 1 ATOM 5112 C CB . TYR A 1 726 ? 0.269 -31.986 -15.644 1.00 108.40 ? 726 TYR A CB 1 ATOM 5113 C CG . TYR A 1 726 ? 1.666 -31.912 -15.069 1.00 115.98 ? 726 TYR A CG 1 ATOM 5114 C CD1 . TYR A 1 726 ? 2.109 -30.767 -14.422 1.00 114.31 ? 726 TYR A CD1 1 ATOM 5115 C CD2 . TYR A 1 726 ? 2.547 -32.978 -15.186 1.00 124.48 ? 726 TYR A CD2 1 ATOM 5116 C CE1 . TYR A 1 726 ? 3.387 -30.689 -13.901 1.00 117.18 ? 726 TYR A CE1 1 ATOM 5117 C CE2 . TYR A 1 726 ? 3.827 -32.909 -14.667 1.00 126.99 ? 726 TYR A CE2 1 ATOM 5118 C CZ . TYR A 1 726 ? 4.242 -31.762 -14.025 1.00 122.58 ? 726 TYR A CZ 1 ATOM 5119 O OH . TYR A 1 726 ? 5.515 -31.690 -13.507 1.00 118.67 ? 726 TYR A OH 1 ATOM 5120 N N . CYS A 1 727 ? -2.879 -32.335 -15.883 1.00 115.63 ? 727 CYS A N 1 ATOM 5121 C CA . CYS A 1 727 ? -4.099 -31.646 -16.301 1.00 96.23 ? 727 CYS A CA 1 ATOM 5122 C C . CYS A 1 727 ? -5.068 -31.384 -15.154 1.00 95.05 ? 727 CYS A C 1 ATOM 5123 O O . CYS A 1 727 ? -5.274 -32.237 -14.291 1.00 97.08 ? 727 CYS A O 1 ATOM 5124 C CB . CYS A 1 727 ? -4.796 -32.440 -17.407 1.00 101.67 ? 727 CYS A CB 1 ATOM 5125 S SG . CYS A 1 727 ? -3.740 -32.810 -18.827 1.00 113.23 ? 727 CYS A SG 1 ATOM 5126 N N . GLY A 1 728 ? -5.656 -30.192 -15.155 1.00 92.39 ? 728 GLY A N 1 ATOM 5127 C CA . GLY A 1 728 ? -6.550 -29.777 -14.093 1.00 93.23 ? 728 GLY A CA 1 ATOM 5128 C C . GLY A 1 728 ? -5.882 -28.767 -13.181 1.00 87.32 ? 728 GLY A C 1 ATOM 5129 O O . GLY A 1 728 ? -6.542 -28.107 -12.380 1.00 82.63 ? 728 GLY A O 1 ATOM 5130 N N . SER A 1 729 ? -4.563 -28.649 -13.305 1.00 91.44 ? 729 SER A N 1 ATOM 5131 C CA . SER A 1 729 ? -3.804 -27.702 -12.497 1.00 79.99 ? 729 SER A CA 1 ATOM 5132 C C . SER A 1 729 ? -3.834 -26.310 -13.122 1.00 73.13 ? 729 SER A C 1 ATOM 5133 O O . SER A 1 729 ? -4.406 -26.117 -14.193 1.00 79.69 ? 729 SER A O 1 ATOM 5134 C CB . SER A 1 729 ? -2.357 -28.176 -12.333 1.00 75.40 ? 729 SER A CB 1 ATOM 5135 O OG . SER A 1 729 ? -1.672 -28.184 -13.573 1.00 77.39 ? 729 SER A OG 1 ATOM 5136 N N . VAL A 1 730 ? -3.217 -25.341 -12.451 1.00 59.17 ? 730 VAL A N 1 ATOM 5137 C CA . VAL A 1 730 ? -3.147 -23.977 -12.968 1.00 55.60 ? 730 VAL A CA 1 ATOM 5138 C C . VAL A 1 730 ? -1.705 -23.471 -12.956 1.00 60.76 ? 730 VAL A C 1 ATOM 5139 O O . VAL A 1 730 ? -0.949 -23.764 -12.032 1.00 70.77 ? 730 VAL A O 1 ATOM 5140 C CB . VAL A 1 730 ? -4.020 -23.008 -12.140 1.00 50.44 ? 730 VAL A CB 1 ATOM 5141 C CG1 . VAL A 1 730 ? -4.174 -21.682 -12.864 1.00 45.75 ? 730 VAL A CG1 1 ATOM 5142 C CG2 . VAL A 1 730 ? -5.383 -23.613 -11.869 1.00 58.94 ? 730 VAL A CG2 1 ATOM 5143 N N . PHE A 1 731 ? -1.326 -22.721 -13.987 1.00 58.53 ? 731 PHE A N 1 ATOM 5144 C CA . PHE A 1 731 ? -0.008 -22.095 -14.039 1.00 54.53 ? 731 PHE A CA 1 ATOM 5145 C C . PHE A 1 731 ? -0.138 -20.611 -13.717 1.00 55.98 ? 731 PHE A C 1 ATOM 5146 O O . PHE A 1 731 ? -0.788 -19.865 -14.450 1.00 55.58 ? 731 PHE A O 1 ATOM 5147 C CB . PHE A 1 731 ? 0.622 -22.289 -15.420 1.00 56.94 ? 731 PHE A CB 1 ATOM 5148 C CG . PHE A 1 731 ? 2.000 -21.697 -15.557 1.00 57.75 ? 731 PHE A CG 1 ATOM 5149 C CD1 . PHE A 1 731 ? 2.172 -20.402 -16.024 1.00 59.55 ? 731 PHE A CD1 1 ATOM 5150 C CD2 . PHE A 1 731 ? 3.123 -22.441 -15.238 1.00 63.26 ? 731 PHE A CD2 1 ATOM 5151 C CE1 . PHE A 1 731 ? 3.435 -19.857 -16.156 1.00 58.30 ? 731 PHE A CE1 1 ATOM 5152 C CE2 . PHE A 1 731 ? 4.389 -21.902 -15.370 1.00 70.49 ? 731 PHE A CE2 1 ATOM 5153 C CZ . PHE A 1 731 ? 4.545 -20.608 -15.830 1.00 70.23 ? 731 PHE A CZ 1 ATOM 5154 N N . LEU A 1 732 ? 0.477 -20.187 -12.617 1.00 55.71 ? 732 LEU A N 1 ATOM 5155 C CA . LEU A 1 732 ? 0.374 -18.803 -12.169 1.00 51.56 ? 732 LEU A CA 1 ATOM 5156 C C . LEU A 1 732 ? 1.708 -18.072 -12.312 1.00 54.66 ? 732 LEU A C 1 ATOM 5157 O O . LEU A 1 732 ? 2.653 -18.338 -11.570 1.00 63.64 ? 732 LEU A O 1 ATOM 5158 C CB . LEU A 1 732 ? -0.122 -18.761 -10.717 1.00 46.36 ? 732 LEU A CB 1 ATOM 5159 C CG . LEU A 1 732 ? -0.235 -17.430 -9.968 1.00 43.46 ? 732 LEU A CG 1 ATOM 5160 C CD1 . LEU A 1 732 ? -0.755 -16.331 -10.870 1.00 47.61 ? 732 LEU A CD1 1 ATOM 5161 C CD2 . LEU A 1 732 ? -1.142 -17.588 -8.751 1.00 33.67 ? 732 LEU A CD2 1 ATOM 5162 N N . ARG A 1 733 ? 1.770 -17.144 -13.263 1.00 56.66 ? 733 ARG A N 1 ATOM 5163 C CA . ARG A 1 733 ? 2.979 -16.361 -13.502 1.00 59.97 ? 733 ARG A CA 1 ATOM 5164 C C . ARG A 1 733 ? 2.814 -14.948 -12.954 1.00 64.37 ? 733 ARG A C 1 ATOM 5165 O O . ARG A 1 733 ? 1.755 -14.336 -13.099 1.00 60.11 ? 733 ARG A O 1 ATOM 5166 C CB . ARG A 1 733 ? 3.314 -16.309 -14.995 1.00 57.69 ? 733 ARG A CB 1 ATOM 5167 C CG . ARG A 1 733 ? 4.728 -15.820 -15.287 1.00 67.13 ? 733 ARG A CG 1 ATOM 5168 C CD . ARG A 1 733 ? 4.998 -15.675 -16.778 1.00 72.67 ? 733 ARG A CD 1 ATOM 5169 N NE . ARG A 1 733 ? 4.416 -14.455 -17.334 1.00 74.99 ? 733 ARG A NE 1 ATOM 5170 C CZ . ARG A 1 733 ? 5.010 -13.265 -17.309 1.00 80.98 ? 733 ARG A CZ 1 ATOM 5171 N NH1 . ARG A 1 733 ? 6.203 -13.127 -16.749 1.00 83.99 ? 733 ARG A NH1 1 ATOM 5172 N NH2 . ARG A 1 733 ? 4.408 -12.210 -17.841 1.00 81.03 ? 733 ARG A NH2 1 ATOM 5173 N N . TYR A 1 734 ? 3.870 -14.434 -12.331 1.00 77.61 ? 734 TYR A N 1 ATOM 5174 C CA . TYR A 1 734 ? 3.815 -13.149 -11.643 1.00 79.86 ? 734 TYR A CA 1 ATOM 5175 C C . TYR A 1 734 ? 5.202 -12.527 -11.522 1.00 77.96 ? 734 TYR A C 1 ATOM 5176 O O . TYR A 1 734 ? 6.213 -13.220 -11.634 1.00 73.00 ? 734 TYR A O 1 ATOM 5177 C CB . TYR A 1 734 ? 3.214 -13.329 -10.248 1.00 77.91 ? 734 TYR A CB 1 ATOM 5178 C CG . TYR A 1 734 ? 4.092 -14.125 -9.308 1.00 73.38 ? 734 TYR A CG 1 ATOM 5179 C CD1 . TYR A 1 734 ? 4.250 -15.495 -9.466 1.00 71.11 ? 734 TYR A CD1 1 ATOM 5180 C CD2 . TYR A 1 734 ? 4.756 -13.510 -8.258 1.00 74.63 ? 734 TYR A CD2 1 ATOM 5181 C CE1 . TYR A 1 734 ? 5.050 -16.222 -8.614 1.00 74.36 ? 734 TYR A CE1 1 ATOM 5182 C CE2 . TYR A 1 734 ? 5.557 -14.234 -7.399 1.00 84.71 ? 734 TYR A CE2 1 ATOM 5183 C CZ . TYR A 1 734 ? 5.700 -15.590 -7.581 1.00 86.29 ? 734 TYR A CZ 1 ATOM 5184 O OH . TYR A 1 734 ? 6.495 -16.320 -6.728 1.00 91.20 ? 734 TYR A OH 1 ATOM 5185 N N . LEU A 1 735 ? 5.244 -11.219 -11.285 1.00 78.66 ? 735 LEU A N 1 ATOM 5186 C CA . LEU A 1 735 ? 6.508 -10.526 -11.078 1.00 81.81 ? 735 LEU A CA 1 ATOM 5187 C C . LEU A 1 735 ? 6.783 -10.368 -9.588 1.00 91.43 ? 735 LEU A C 1 ATOM 5188 O O . LEU A 1 735 ? 5.968 -10.759 -8.752 1.00 84.73 ? 735 LEU A O 1 ATOM 5189 C CB . LEU A 1 735 ? 6.489 -9.150 -11.749 1.00 76.63 ? 735 LEU A CB 1 ATOM 5190 C CG . LEU A 1 735 ? 6.171 -9.102 -13.245 1.00 64.37 ? 735 LEU A CG 1 ATOM 5191 C CD1 . LEU A 1 735 ? 6.356 -7.692 -13.789 1.00 62.75 ? 735 LEU A CD1 1 ATOM 5192 C CD2 . LEU A 1 735 ? 7.031 -10.093 -14.007 1.00 75.70 ? 735 LEU A CD2 1 ATOM 5193 N N . THR A 1 736 ? 7.932 -9.786 -9.262 1.00 98.24 ? 736 THR A N 1 ATOM 5194 C CA . THR A 1 736 ? 8.304 -9.543 -7.872 1.00 93.10 ? 736 THR A CA 1 ATOM 5195 C C . THR A 1 736 ? 7.831 -8.160 -7.435 1.00 89.40 ? 736 THR A C 1 ATOM 5196 O O . THR A 1 736 ? 8.083 -7.727 -6.310 1.00 86.11 ? 736 THR A O 1 ATOM 5197 C CB . THR A 1 736 ? 9.821 -9.686 -7.658 1.00 93.25 ? 736 THR A CB 1 ATOM 5198 O OG1 . THR A 1 736 ? 10.521 -8.844 -8.581 1.00 97.35 ? 736 THR A OG1 1 ATOM 5199 C CG2 . THR A 1 736 ? 10.251 -11.128 -7.881 1.00 91.93 ? 736 THR A CG2 1 ATOM 5200 N N . THR A 1 737 ? 7.136 -7.478 -8.341 1.00 88.28 ? 737 THR A N 1 ATOM 5201 C CA . THR A 1 737 ? 6.558 -6.171 -8.057 1.00 89.73 ? 737 THR A CA 1 ATOM 5202 C C . THR A 1 737 ? 5.227 -6.344 -7.335 1.00 93.75 ? 737 THR A C 1 ATOM 5203 O O . THR A 1 737 ? 4.574 -5.367 -6.972 1.00 93.67 ? 737 THR A O 1 ATOM 5204 C CB . THR A 1 737 ? 6.323 -5.360 -9.349 1.00 85.57 ? 737 THR A CB 1 ATOM 5205 O OG1 . THR A 1 737 ? 5.198 -5.892 -10.057 1.00 84.76 ? 737 THR A OG1 1 ATOM 5206 C CG2 . THR A 1 737 ? 7.552 -5.405 -10.247 1.00 85.26 ? 737 THR A CG2 1 ATOM 5207 N N . GLY A 1 738 ? 4.828 -7.597 -7.136 1.00 93.28 ? 738 GLY A N 1 ATOM 5208 C CA . GLY A 1 738 ? 3.571 -7.902 -6.482 1.00 86.63 ? 738 GLY A CA 1 ATOM 5209 C C . GLY A 1 738 ? 2.460 -8.075 -7.492 1.00 85.98 ? 738 GLY A C 1 ATOM 5210 O O . GLY A 1 738 ? 1.383 -8.581 -7.175 1.00 87.47 ? 738 GLY A O 1 ATOM 5211 N N . ALA A 1 739 ? 2.733 -7.649 -8.719 1.00 83.36 ? 739 ALA A N 1 ATOM 5212 C CA . ALA A 1 739 ? 1.766 -7.743 -9.799 1.00 81.81 ? 739 ALA A CA 1 ATOM 5213 C C . ALA A 1 739 ? 1.511 -9.195 -10.184 1.00 79.35 ? 739 ALA A C 1 ATOM 5214 O O . ALA A 1 739 ? 2.362 -10.063 -9.987 1.00 77.35 ? 739 ALA A O 1 ATOM 5215 C CB . ALA A 1 739 ? 2.245 -6.952 -11.002 1.00 79.11 ? 739 ALA A CB 1 ATOM 5216 N N . ILE A 1 740 ? 0.328 -9.448 -10.732 1.00 74.64 ? 740 ILE A N 1 ATOM 5217 C CA . ILE A 1 740 ? -0.021 -10.763 -11.245 1.00 64.90 ? 740 ILE A CA 1 ATOM 5218 C C . ILE A 1 740 ? -0.117 -10.656 -12.760 1.00 65.64 ? 740 ILE A C 1 ATOM 5219 O O . ILE A 1 740 ? -0.586 -9.645 -13.283 1.00 65.35 ? 740 ILE A O 1 ATOM 5220 C CB . ILE A 1 740 ? -1.357 -11.248 -10.667 1.00 53.21 ? 740 ILE A CB 1 ATOM 5221 C CG1 . ILE A 1 740 ? -1.511 -10.762 -9.224 1.00 56.03 ? 740 ILE A CG1 1 ATOM 5222 C CG2 . ILE A 1 740 ? -1.450 -12.761 -10.741 1.00 49.86 ? 740 ILE A CG2 1 ATOM 5223 C CD1 . ILE A 1 740 ? -2.760 -11.258 -8.541 1.00 59.62 ? 740 ILE A CD1 1 ATOM 5224 N N . MET A 1 741 ? 0.334 -11.686 -13.468 1.00 64.53 ? 741 MET A N 1 ATOM 5225 C CA . MET A 1 741 ? 0.410 -11.610 -14.922 1.00 63.59 ? 741 MET A CA 1 ATOM 5226 C C . MET A 1 741 ? -0.519 -12.578 -15.649 1.00 68.16 ? 741 MET A C 1 ATOM 5227 O O . MET A 1 741 ? -1.549 -12.174 -16.190 1.00 67.24 ? 741 MET A O 1 ATOM 5228 C CB . MET A 1 741 ? 1.852 -11.824 -15.386 1.00 60.97 ? 741 MET A CB 1 ATOM 5229 C CG . MET A 1 741 ? 2.768 -10.669 -15.047 1.00 65.67 ? 741 MET A CG 1 ATOM 5230 S SD . MET A 1 741 ? 2.271 -9.160 -15.898 1.00 66.06 ? 741 MET A SD 1 ATOM 5231 C CE . MET A 1 741 ? 2.175 -8.013 -14.526 1.00 60.43 ? 741 MET A CE 1 ATOM 5232 N N . ASP A 1 742 ? -0.155 -13.854 -15.657 1.00 69.66 ? 742 ASP A N 1 ATOM 5233 C CA . ASP A 1 742 ? -0.889 -14.836 -16.442 1.00 65.09 ? 742 ASP A CA 1 ATOM 5234 C C . ASP A 1 742 ? -1.410 -15.986 -15.586 1.00 59.64 ? 742 ASP A C 1 ATOM 5235 O O . ASP A 1 742 ? -0.640 -16.665 -14.907 1.00 61.98 ? 742 ASP A O 1 ATOM 5236 C CB . ASP A 1 742 ? -0.001 -15.380 -17.568 1.00 63.72 ? 742 ASP A CB 1 ATOM 5237 C CG . ASP A 1 742 ? 0.581 -14.278 -18.438 1.00 68.56 ? 742 ASP A CG 1 ATOM 5238 O OD1 . ASP A 1 742 ? -0.075 -13.225 -18.582 1.00 70.94 ? 742 ASP A OD1 1 ATOM 5239 O OD2 . ASP A 1 742 ? 1.693 -14.462 -18.979 1.00 69.82 ? 742 ASP A OD2 1 ATOM 5240 N N . ILE A 1 743 ? -2.721 -16.200 -15.618 1.00 58.99 ? 743 ILE A N 1 ATOM 5241 C CA . ILE A 1 743 ? -3.303 -17.395 -15.024 1.00 60.09 ? 743 ILE A CA 1 ATOM 5242 C C . ILE A 1 743 ? -3.606 -18.351 -16.171 1.00 64.83 ? 743 ILE A C 1 ATOM 5243 O O . ILE A 1 743 ? -4.513 -18.104 -16.963 1.00 66.19 ? 743 ILE A O 1 ATOM 5244 C CB . ILE A 1 743 ? -4.621 -17.087 -14.275 1.00 58.68 ? 743 ILE A CB 1 ATOM 5245 C CG1 . ILE A 1 743 ? -4.645 -15.641 -13.767 1.00 57.99 ? 743 ILE A CG1 1 ATOM 5246 C CG2 . ILE A 1 743 ? -4.848 -18.080 -13.138 1.00 40.25 ? 743 ILE A CG2 1 ATOM 5247 C CD1 . ILE A 1 743 ? -3.725 -15.379 -12.597 1.00 58.20 ? 743 ILE A CD1 1 ATOM 5248 N N . ILE A 1 744 ? -2.843 -19.434 -16.277 1.00 61.79 ? 744 ILE A N 1 ATOM 5249 C CA . ILE A 1 744 ? -3.082 -20.422 -17.330 1.00 61.21 ? 744 ILE A CA 1 ATOM 5250 C C . ILE A 1 744 ? -3.479 -21.769 -16.730 1.00 66.55 ? 744 ILE A C 1 ATOM 5251 O O . ILE A 1 744 ? -2.796 -22.295 -15.850 1.00 71.26 ? 744 ILE A O 1 ATOM 5252 C CB . ILE A 1 744 ? -1.864 -20.587 -18.279 1.00 51.03 ? 744 ILE A CB 1 ATOM 5253 C CG1 . ILE A 1 744 ? -1.967 -19.634 -19.470 1.00 47.91 ? 744 ILE A CG1 1 ATOM 5254 C CG2 . ILE A 1 744 ? -1.791 -21.998 -18.826 1.00 49.61 ? 744 ILE A CG2 1 ATOM 5255 C CD1 . ILE A 1 744 ? -1.899 -18.173 -19.113 1.00 57.68 ? 744 ILE A CD1 1 ATOM 5256 N N . ILE A 1 745 ? -4.603 -22.308 -17.192 1.00 69.73 ? 745 ILE A N 1 ATOM 5257 C CA . ILE A 1 745 ? -5.036 -23.640 -16.796 1.00 70.94 ? 745 ILE A CA 1 ATOM 5258 C C . ILE A 1 745 ? -4.467 -24.628 -17.803 1.00 78.75 ? 745 ILE A C 1 ATOM 5259 O O . ILE A 1 745 ? -4.438 -24.342 -18.999 1.00 85.60 ? 745 ILE A O 1 ATOM 5260 C CB . ILE A 1 745 ? -6.575 -23.751 -16.799 1.00 71.81 ? 745 ILE A CB 1 ATOM 5261 C CG1 . ILE A 1 745 ? -7.200 -22.579 -16.038 1.00 66.22 ? 745 ILE A CG1 1 ATOM 5262 C CG2 . ILE A 1 745 ? -7.022 -25.075 -16.200 1.00 76.46 ? 745 ILE A CG2 1 ATOM 5263 C CD1 . ILE A 1 745 ? -8.711 -22.573 -16.065 1.00 52.59 ? 745 ILE A CD1 1 ATOM 5264 N N . ILE A 1 746 ? -4.008 -25.784 -17.335 1.00 79.93 ? 746 ILE A N 1 ATOM 5265 C CA . ILE A 1 746 ? -3.567 -26.812 -18.264 1.00 89.92 ? 746 ILE A CA 1 ATOM 5266 C C . ILE A 1 746 ? -4.774 -27.695 -18.540 1.00 99.29 ? 746 ILE A C 1 ATOM 5267 O O . ILE A 1 746 ? -5.218 -28.452 -17.676 1.00 99.68 ? 746 ILE A O 1 ATOM 5268 C CB . ILE A 1 746 ? -2.401 -27.651 -17.695 1.00 85.66 ? 746 ILE A CB 1 ATOM 5269 C CG1 . ILE A 1 746 ? -1.113 -26.825 -17.651 1.00 87.62 ? 746 ILE A CG1 1 ATOM 5270 C CG2 . ILE A 1 746 ? -2.173 -28.897 -18.533 1.00 95.83 ? 746 ILE A CG2 1 ATOM 5271 C CD1 . ILE A 1 746 ? -0.750 -26.316 -16.274 1.00 84.88 ? 746 ILE A CD1 1 ATOM 5272 N N . ASP A 1 747 ? -5.311 -27.570 -19.751 1.00 98.86 ? 747 ASP A N 1 ATOM 5273 C CA . ASP A 1 747 ? -6.521 -28.280 -20.147 1.00 90.13 ? 747 ASP A CA 1 ATOM 5274 C C . ASP A 1 747 ? -6.245 -29.702 -20.613 1.00 88.62 ? 747 ASP A C 1 ATOM 5275 O O . ASP A 1 747 ? -6.952 -30.640 -20.244 1.00 84.76 ? 747 ASP A O 1 ATOM 5276 C CB . ASP A 1 747 ? -7.239 -27.512 -21.262 1.00 93.39 ? 747 ASP A CB 1 ATOM 5277 C CG . ASP A 1 747 ? -6.349 -27.264 -22.467 1.00 94.00 ? 747 ASP A CG 1 ATOM 5278 O OD1 . ASP A 1 747 ? -5.198 -26.821 -22.277 1.00 88.99 ? 747 ASP A OD1 1 ATOM 5279 O OD2 . ASP A 1 747 ? -6.796 -27.522 -23.605 1.00 98.58 ? 747 ASP A OD2 1 ATOM 5280 N N . SER A 1 748 ? -5.202 -29.848 -21.421 1.00 93.89 ? 748 SER A N 1 ATOM 5281 C CA . SER A 1 748 ? -4.961 -31.086 -22.145 1.00 100.60 ? 748 SER A CA 1 ATOM 5282 C C . SER A 1 748 ? -3.487 -31.451 -22.173 1.00 97.82 ? 748 SER A C 1 ATOM 5283 O O . SER A 1 748 ? -2.626 -30.647 -21.818 1.00 94.94 ? 748 SER A O 1 ATOM 5284 C CB . SER A 1 748 ? -5.490 -30.967 -23.576 1.00 106.27 ? 748 SER A CB 1 ATOM 5285 O OG . SER A 1 748 ? -4.850 -29.905 -24.266 1.00 105.52 ? 748 SER A OG 1 ATOM 5286 N N . LYS A 1 749 ? -3.209 -32.674 -22.606 1.00 99.60 ? 749 LYS A N 1 ATOM 5287 C CA . LYS A 1 749 ? -1.845 -33.170 -22.699 1.00 108.94 ? 749 LYS A CA 1 ATOM 5288 C C . LYS A 1 749 ? -1.071 -32.411 -23.771 1.00 106.77 ? 749 LYS A C 1 ATOM 5289 O O . LYS A 1 749 ? 0.158 -32.355 -23.740 1.00 108.64 ? 749 LYS A O 1 ATOM 5290 C CB . LYS A 1 749 ? -1.859 -34.661 -23.019 1.00 122.51 ? 749 LYS A CB 1 ATOM 5291 C CG . LYS A 1 749 ? -0.784 -35.464 -22.320 1.00 131.01 ? 749 LYS A CG 1 ATOM 5292 C CD . LYS A 1 749 ? -0.918 -36.932 -22.665 1.00 138.68 ? 749 LYS A CD 1 ATOM 5293 C CE . LYS A 1 749 ? -2.335 -37.433 -22.414 1.00 135.94 ? 749 LYS A CE 1 ATOM 5294 N NZ . LYS A 1 749 ? -2.500 -38.863 -22.801 1.00 134.31 ? 749 LYS A NZ 1 ATOM 5295 N N . ASP A 1 750 ? -1.800 -31.831 -24.719 1.00 102.89 ? 750 ASP A N 1 ATOM 5296 C CA . ASP A 1 750 ? -1.197 -31.005 -25.757 1.00 105.53 ? 750 ASP A CA 1 ATOM 5297 C C . ASP A 1 750 ? -0.619 -29.729 -25.148 1.00 101.53 ? 750 ASP A C 1 ATOM 5298 O O . ASP A 1 750 ? 0.442 -29.259 -25.557 1.00 98.89 ? 750 ASP A O 1 ATOM 5299 C CB . ASP A 1 750 ? -2.229 -30.659 -26.834 1.00 111.34 ? 750 ASP A CB 1 ATOM 5300 C CG . ASP A 1 750 ? -2.779 -31.889 -27.536 1.00 118.35 ? 750 ASP A CG 1 ATOM 5301 O OD1 . ASP A 1 750 ? -2.162 -32.338 -28.525 1.00 125.48 ? 750 ASP A OD1 1 ATOM 5302 O OD2 . ASP A 1 750 ? -3.832 -32.403 -27.102 1.00 111.57 ? 750 ASP A OD2 1 ATOM 5303 N N . THR A 1 751 ? -1.328 -29.176 -24.168 1.00 101.58 ? 751 THR A N 1 ATOM 5304 C CA . THR A 1 751 ? -0.868 -27.989 -23.454 1.00 99.12 ? 751 THR A CA 1 ATOM 5305 C C . THR A 1 751 ? 0.203 -28.369 -22.437 1.00 104.08 ? 751 THR A C 1 ATOM 5306 O O . THR A 1 751 ? 1.193 -27.656 -22.266 1.00 104.51 ? 751 THR A O 1 ATOM 5307 C CB . THR A 1 751 ? -2.027 -27.287 -22.718 1.00 99.66 ? 751 THR A CB 1 ATOM 5308 O OG1 . THR A 1 751 ? -3.069 -26.968 -23.649 1.00 104.18 ? 751 THR A OG1 1 ATOM 5309 C CG2 . THR A 1 751 ? -1.545 -26.009 -22.049 1.00 93.60 ? 751 THR A CG2 1 ATOM 5310 N N . GLU A 1 752 ? -0.008 -29.498 -21.766 1.00 106.93 ? 752 GLU A N 1 ATOM 5311 C CA . GLU A 1 752 ? 0.936 -30.013 -20.778 1.00 101.50 ? 752 GLU A CA 1 ATOM 5312 C C . GLU A 1 752 ? 2.321 -30.206 -21.386 1.00 99.82 ? 752 GLU A C 1 ATOM 5313 O O . GLU A 1 752 ? 3.332 -29.906 -20.752 1.00 101.40 ? 752 GLU A O 1 ATOM 5314 C CB . GLU A 1 752 ? 0.427 -31.337 -20.203 1.00 103.35 ? 752 GLU A CB 1 ATOM 5315 C CG . GLU A 1 752 ? 1.352 -31.983 -19.181 1.00 99.76 ? 752 GLU A CG 1 ATOM 5316 C CD . GLU A 1 752 ? 0.954 -33.412 -18.868 1.00 112.01 ? 752 GLU A CD 1 ATOM 5317 O OE1 . GLU A 1 752 ? 0.112 -33.963 -19.603 1.00 118.70 ? 752 GLU A OE1 1 ATOM 5318 O OE2 . GLU A 1 752 ? 1.482 -33.986 -17.893 1.00 113.86 ? 752 GLU A OE2 1 ATOM 5319 N N . ARG A 1 753 ? 2.357 -30.707 -22.617 1.00 106.03 ? 753 ARG A N 1 ATOM 5320 C CA . ARG A 1 753 ? 3.609 -30.878 -23.348 1.00 107.20 ? 753 ARG A CA 1 ATOM 5321 C C . ARG A 1 753 ? 4.256 -29.533 -23.655 1.00 105.12 ? 753 ARG A C 1 ATOM 5322 O O . ARG A 1 753 ? 5.480 -29.401 -23.628 1.00 109.45 ? 753 ARG A O 1 ATOM 5323 C CB . ARG A 1 753 ? 3.375 -31.648 -24.650 1.00 117.71 ? 753 ARG A CB 1 ATOM 5324 C CG . ARG A 1 753 ? 3.190 -33.146 -24.467 1.00 129.61 ? 753 ARG A CG 1 ATOM 5325 C CD . ARG A 1 753 ? 2.998 -33.852 -25.801 1.00 132.18 ? 753 ARG A CD 1 ATOM 5326 N NE . ARG A 1 753 ? 2.994 -35.305 -25.649 1.00 142.60 ? 753 ARG A NE 1 ATOM 5327 C CZ . ARG A 1 753 ? 1.912 -36.025 -25.370 1.00 134.39 ? 753 ARG A CZ 1 ATOM 5328 N NH1 . ARG A 1 753 ? 0.739 -35.428 -25.212 1.00 123.54 ? 753 ARG A NH1 1 ATOM 5329 N NH2 . ARG A 1 753 ? 2.003 -37.342 -25.249 1.00 136.24 ? 753 ARG A NH2 1 ATOM 5330 N N . GLN A 1 754 ? 3.425 -28.539 -23.954 1.00 102.08 ? 754 GLN A N 1 ATOM 5331 C CA . GLN A 1 754 ? 3.907 -27.191 -24.235 1.00 101.73 ? 754 GLN A CA 1 ATOM 5332 C C . GLN A 1 754 ? 4.582 -26.571 -23.013 1.00 99.26 ? 754 GLN A C 1 ATOM 5333 O O . GLN A 1 754 ? 5.470 -25.733 -23.148 1.00 98.91 ? 754 GLN A O 1 ATOM 5334 C CB . GLN A 1 754 ? 2.764 -26.298 -24.727 1.00 104.10 ? 754 GLN A CB 1 ATOM 5335 C CG . GLN A 1 754 ? 2.263 -26.642 -26.122 1.00 99.36 ? 754 GLN A CG 1 ATOM 5336 C CD . GLN A 1 754 ? 3.314 -26.416 -27.190 1.00 96.16 ? 754 GLN A CD 1 ATOM 5337 O OE1 . GLN A 1 754 ? 3.978 -25.380 -27.214 1.00 88.34 ? 754 GLN A OE1 1 ATOM 5338 N NE2 . GLN A 1 754 ? 3.475 -27.391 -28.077 1.00 100.47 ? 754 GLN A NE2 1 ATOM 5339 N N . LEU A 1 755 ? 4.161 -26.987 -21.823 1.00 100.69 ? 755 LEU A N 1 ATOM 5340 C CA . LEU A 1 755 ? 4.781 -26.512 -20.589 1.00 100.87 ? 755 LEU A CA 1 ATOM 5341 C C . LEU A 1 755 ? 6.209 -27.035 -20.449 1.00 100.79 ? 755 LEU A C 1 ATOM 5342 O O . LEU A 1 755 ? 7.114 -26.295 -20.064 1.00 93.33 ? 755 LEU A O 1 ATOM 5343 C CB . LEU A 1 755 ? 3.945 -26.914 -19.368 1.00 99.69 ? 755 LEU A CB 1 ATOM 5344 C CG . LEU A 1 755 ? 4.553 -26.623 -17.992 1.00 90.94 ? 755 LEU A CG 1 ATOM 5345 C CD1 . LEU A 1 755 ? 4.878 -25.147 -17.842 1.00 83.76 ? 755 LEU A CD1 1 ATOM 5346 C CD2 . LEU A 1 755 ? 3.630 -27.085 -16.870 1.00 93.61 ? 755 LEU A CD2 1 ATOM 5347 N N . ALA A 1 756 ? 6.401 -28.311 -20.774 1.00 105.54 ? 756 ALA A N 1 ATOM 5348 C CA . ALA A 1 756 ? 7.701 -28.965 -20.643 1.00 100.14 ? 756 ALA A CA 1 ATOM 5349 C C . ALA A 1 756 ? 8.777 -28.322 -21.513 1.00 104.11 ? 756 ALA A C 1 ATOM 5350 O O . ALA A 1 756 ? 9.969 -28.469 -21.246 1.00 117.26 ? 756 ALA A O 1 ATOM 5351 C CB . ALA A 1 756 ? 7.582 -30.451 -20.960 1.00 106.02 ? 756 ALA A CB 1 ATOM 5352 N N . ALA A 1 757 ? 8.356 -27.606 -22.550 1.00 98.98 ? 757 ALA A N 1 ATOM 5353 C CA . ALA A 1 757 ? 9.297 -26.943 -23.441 1.00 101.14 ? 757 ALA A CA 1 ATOM 5354 C C . ALA A 1 757 ? 9.401 -25.456 -23.120 1.00 100.46 ? 757 ALA A C 1 ATOM 5355 O O . ALA A 1 757 ? 8.466 -24.693 -23.352 1.00 104.19 ? 757 ALA A O 1 ATOM 5356 C CB . ALA A 1 757 ? 8.887 -27.146 -24.889 1.00 97.19 ? 757 ALA A CB 1 ATOM 5357 N N . MET A 1 758 ? 10.547 -25.050 -22.585 1.00 106.63 ? 758 MET A N 1 ATOM 5358 C CA . MET A 1 758 ? 10.781 -23.650 -22.260 1.00 109.58 ? 758 MET A CA 1 ATOM 5359 C C . MET A 1 758 ? 11.524 -22.969 -23.403 1.00 108.36 ? 758 MET A C 1 ATOM 5360 O O . MET A 1 758 ? 12.684 -23.277 -23.673 1.00 119.27 ? 758 MET A O 1 ATOM 5361 C CB . MET A 1 758 ? 11.563 -23.529 -20.960 1.00 113.19 ? 758 MET A CB 1 ATOM 5362 N N . GLY A 1 759 ? 10.849 -22.039 -24.067 1.00 98.11 ? 759 GLY A N 1 ATOM 5363 C CA . GLY A 1 759 ? 11.407 -21.371 -25.229 1.00 100.60 ? 759 GLY A CA 1 ATOM 5364 C C . GLY A 1 759 ? 10.951 -22.030 -26.512 1.00 111.09 ? 759 GLY A C 1 ATOM 5365 O O . GLY A 1 759 ? 10.925 -21.402 -27.570 1.00 118.21 ? 759 GLY A O 1 ATOM 5366 N N . ASN A 1 760 ? 10.576 -23.301 -26.413 1.00 108.74 ? 760 ASN A N 1 ATOM 5367 C CA . ASN A 1 760 ? 10.019 -24.026 -27.547 1.00 113.24 ? 760 ASN A CA 1 ATOM 5368 C C . ASN A 1 760 ? 8.495 -24.050 -27.520 1.00 113.50 ? 760 ASN A C 1 ATOM 5369 O O . ASN A 1 760 ? 7.858 -24.595 -28.421 1.00 121.62 ? 760 ASN A O 1 ATOM 5370 C CB . ASN A 1 760 ? 10.574 -25.452 -27.608 1.00 115.83 ? 760 ASN A CB 1 ATOM 5371 C CG . ASN A 1 760 ? 11.850 -25.548 -28.426 1.00 127.32 ? 760 ASN A CG 1 ATOM 5372 O OD1 . ASN A 1 760 ? 12.042 -24.804 -29.388 1.00 129.18 ? 760 ASN A OD1 1 ATOM 5373 N ND2 . ASN A 1 760 ? 12.726 -26.474 -28.051 1.00 134.04 ? 760 ASN A ND2 1 ATOM 5374 N N . SER A 1 761 ? 7.914 -23.455 -26.482 1.00 110.41 ? 761 SER A N 1 ATOM 5375 C CA . SER A 1 761 ? 6.463 -23.435 -26.331 1.00 102.61 ? 761 SER A CA 1 ATOM 5376 C C . SER A 1 761 ? 5.826 -22.369 -27.206 1.00 100.07 ? 761 SER A C 1 ATOM 5377 O O . SER A 1 761 ? 6.392 -21.295 -27.408 1.00 104.69 ? 761 SER A O 1 ATOM 5378 C CB . SER A 1 761 ? 6.070 -23.192 -24.874 1.00 100.95 ? 761 SER A CB 1 ATOM 5379 O OG . SER A 1 761 ? 6.377 -21.868 -24.476 1.00 105.41 ? 761 SER A OG 1 ATOM 5380 N N . THR A 1 762 ? 4.641 -22.677 -27.720 1.00 91.40 ? 762 THR A N 1 ATOM 5381 C CA . THR A 1 762 ? 3.862 -21.714 -28.484 1.00 91.03 ? 762 THR A CA 1 ATOM 5382 C C . THR A 1 762 ? 3.112 -20.783 -27.539 1.00 90.90 ? 762 THR A C 1 ATOM 5383 O O . THR A 1 762 ? 2.596 -19.745 -27.953 1.00 87.77 ? 762 THR A O 1 ATOM 5384 C CB . THR A 1 762 ? 2.850 -22.414 -29.410 1.00 96.07 ? 762 THR A CB 1 ATOM 5385 O OG1 . THR A 1 762 ? 2.129 -23.407 -28.670 1.00 95.29 ? 762 THR A OG1 1 ATOM 5386 C CG2 . THR A 1 762 ? 3.565 -23.081 -30.577 1.00 93.45 ? 762 THR A CG2 1 ATOM 5387 N N . ILE A 1 763 ? 3.064 -21.164 -26.265 1.00 92.37 ? 763 ILE A N 1 ATOM 5388 C CA . ILE A 1 763 ? 2.344 -20.409 -25.247 1.00 86.14 ? 763 ILE A CA 1 ATOM 5389 C C . ILE A 1 763 ? 3.309 -19.525 -24.457 1.00 84.12 ? 763 ILE A C 1 ATOM 5390 O O . ILE A 1 763 ? 4.102 -20.029 -23.663 1.00 89.93 ? 763 ILE A O 1 ATOM 5391 C CB . ILE A 1 763 ? 1.615 -21.364 -24.276 1.00 82.86 ? 763 ILE A CB 1 ATOM 5392 C CG1 . ILE A 1 763 ? 0.978 -22.525 -25.048 1.00 81.62 ? 763 ILE A CG1 1 ATOM 5393 C CG2 . ILE A 1 763 ? 0.572 -20.617 -23.469 1.00 84.06 ? 763 ILE A CG2 1 ATOM 5394 C CD1 . ILE A 1 763 ? 0.298 -23.558 -24.168 1.00 64.93 ? 763 ILE A CD1 1 ATOM 5395 N N . PRO A 1 764 ? 3.241 -18.199 -24.673 1.00 81.82 ? 764 PRO A N 1 ATOM 5396 C CA . PRO A 1 764 ? 4.158 -17.214 -24.073 1.00 82.17 ? 764 PRO A CA 1 ATOM 5397 C C . PRO A 1 764 ? 4.350 -17.234 -22.541 1.00 90.71 ? 764 PRO A C 1 ATOM 5398 O O . PRO A 1 764 ? 5.481 -17.017 -22.106 1.00 102.76 ? 764 PRO A O 1 ATOM 5399 C CB . PRO A 1 764 ? 3.601 -15.857 -24.547 1.00 82.31 ? 764 PRO A CB 1 ATOM 5400 C CG . PRO A 1 764 ? 2.272 -16.149 -25.176 1.00 93.34 ? 764 PRO A CG 1 ATOM 5401 C CD . PRO A 1 764 ? 2.318 -17.571 -25.633 1.00 87.30 ? 764 PRO A CD 1 ATOM 5402 N N . PRO A 1 765 ? 3.290 -17.468 -21.740 1.00 83.85 ? 765 PRO A N 1 ATOM 5403 C CA . PRO A 1 765 ? 3.554 -17.511 -20.295 1.00 85.07 ? 765 PRO A CA 1 ATOM 5404 C C . PRO A 1 765 ? 4.380 -18.722 -19.859 1.00 84.98 ? 765 PRO A C 1 ATOM 5405 O O . PRO A 1 765 ? 5.057 -18.654 -18.833 1.00 81.79 ? 765 PRO A O 1 ATOM 5406 C CB . PRO A 1 765 ? 2.150 -17.592 -19.686 1.00 75.07 ? 765 PRO A CB 1 ATOM 5407 C CG . PRO A 1 765 ? 1.306 -18.164 -20.758 1.00 82.68 ? 765 PRO A CG 1 ATOM 5408 C CD . PRO A 1 765 ? 1.849 -17.584 -22.024 1.00 85.06 ? 765 PRO A CD 1 ATOM 5409 N N . PHE A 1 766 ? 4.319 -19.809 -20.623 1.00 88.26 ? 766 PHE A N 1 ATOM 5410 C CA . PHE A 1 766 ? 5.086 -21.016 -20.315 1.00 94.24 ? 766 PHE A CA 1 ATOM 5411 C C . PHE A 1 766 ? 6.583 -20.870 -20.605 1.00 95.33 ? 766 PHE A C 1 ATOM 5412 O O . PHE A 1 766 ? 7.412 -21.562 -20.013 1.00 89.97 ? 766 PHE A O 1 ATOM 5413 C CB . PHE A 1 766 ? 4.522 -22.211 -21.085 1.00 88.50 ? 766 PHE A CB 1 ATOM 5414 C CG . PHE A 1 766 ? 3.298 -22.811 -20.461 1.00 77.05 ? 766 PHE A CG 1 ATOM 5415 C CD1 . PHE A 1 766 ? 2.891 -22.433 -19.191 1.00 72.72 ? 766 PHE A CD1 1 ATOM 5416 C CD2 . PHE A 1 766 ? 2.559 -23.765 -21.139 1.00 84.50 ? 766 PHE A CD2 1 ATOM 5417 C CE1 . PHE A 1 766 ? 1.766 -22.992 -18.616 1.00 79.06 ? 766 PHE A CE1 1 ATOM 5418 C CE2 . PHE A 1 766 ? 1.434 -24.327 -20.567 1.00 91.51 ? 766 PHE A CE2 1 ATOM 5419 C CZ . PHE A 1 766 ? 1.038 -23.942 -19.304 1.00 81.67 ? 766 PHE A CZ 1 ATOM 5420 N N . ASN A 1 767 ? 6.918 -19.972 -21.524 1.00 91.83 ? 767 ASN A N 1 ATOM 5421 C CA . ASN A 1 767 ? 8.303 -19.724 -21.891 1.00 84.88 ? 767 ASN A CA 1 ATOM 5422 C C . ASN A 1 767 ? 8.803 -18.451 -21.222 1.00 94.46 ? 767 ASN A C 1 ATOM 5423 O O . ASN A 1 767 ? 8.415 -17.352 -21.618 1.00 90.53 ? 767 ASN A O 1 ATOM 5424 C CB . ASN A 1 767 ? 8.400 -19.604 -23.415 1.00 87.61 ? 767 ASN A CB 1 ATOM 5425 C CG . ASN A 1 767 ? 9.647 -18.877 -23.876 1.00 95.10 ? 767 ASN A CG 1 ATOM 5426 O OD1 . ASN A 1 767 ? 10.720 -19.016 -23.291 1.00 100.81 ? 767 ASN A OD1 1 ATOM 5427 N ND2 . ASN A 1 767 ? 9.511 -18.101 -24.944 1.00 98.50 ? 767 ASN A ND2 1 ATOM 5428 N N . PRO A 1 768 ? 9.650 -18.589 -20.186 1.00 104.23 ? 768 PRO A N 1 ATOM 5429 C CA . PRO A 1 768 ? 10.184 -17.356 -19.604 1.00 97.35 ? 768 PRO A CA 1 ATOM 5430 C C . PRO A 1 768 ? 11.484 -16.909 -20.264 1.00 84.31 ? 768 PRO A C 1 ATOM 5431 O O . PRO A 1 768 ? 12.407 -16.509 -19.554 1.00 86.40 ? 768 PRO A O 1 ATOM 5432 C CB . PRO A 1 768 ? 10.470 -17.773 -18.162 1.00 85.09 ? 768 PRO A CB 1 ATOM 5433 C CG . PRO A 1 768 ? 10.868 -19.218 -18.283 1.00 79.89 ? 768 PRO A CG 1 ATOM 5434 C CD . PRO A 1 768 ? 10.065 -19.787 -19.435 1.00 95.07 ? 768 PRO A CD 1 ATOM 5435 N N . ASP A 1 769 ? 11.558 -16.967 -21.590 1.00 89.44 ? 769 ASP A N 1 ATOM 5436 C CA . ASP A 1 769 ? 12.590 -16.250 -22.326 1.00 93.75 ? 769 ASP A CA 1 ATOM 5437 C C . ASP A 1 769 ? 11.987 -15.000 -22.962 1.00 90.83 ? 769 ASP A C 1 ATOM 5438 O O . ASP A 1 769 ? 12.696 -14.165 -23.524 1.00 84.27 ? 769 ASP A O 1 ATOM 5439 C CB . ASP A 1 769 ? 13.227 -17.152 -23.388 1.00 97.88 ? 769 ASP A CB 1 ATOM 5440 C CG . ASP A 1 769 ? 13.777 -18.445 -22.804 1.00 95.30 ? 769 ASP A CG 1 ATOM 5441 O OD1 . ASP A 1 769 ? 14.356 -18.404 -21.698 1.00 94.73 ? 769 ASP A OD1 1 ATOM 5442 O OD2 . ASP A 1 769 ? 13.625 -19.504 -23.449 1.00 96.23 ? 769 ASP A OD2 1 ATOM 5443 N N . MET A 1 770 ? 10.666 -14.887 -22.860 1.00 94.56 ? 770 MET A N 1 ATOM 5444 C CA . MET A 1 770 ? 9.927 -13.762 -23.422 1.00 101.37 ? 770 MET A CA 1 ATOM 5445 C C . MET A 1 770 ? 9.631 -12.727 -22.349 1.00 105.60 ? 770 MET A C 1 ATOM 5446 O O . MET A 1 770 ? 9.031 -11.687 -22.619 1.00 111.11 ? 770 MET A O 1 ATOM 5447 C CB . MET A 1 770 ? 8.622 -14.242 -24.066 1.00 98.37 ? 770 MET A CB 1 ATOM 5448 C CG . MET A 1 770 ? 8.808 -14.948 -25.402 1.00 101.22 ? 770 MET A CG 1 ATOM 5449 S SD . MET A 1 770 ? 7.356 -15.877 -25.939 1.00 106.89 ? 770 MET A SD 1 ATOM 5450 C CE . MET A 1 770 ? 7.908 -16.477 -27.536 1.00 84.06 ? 770 MET A CE 1 ATOM 5451 N N . HIS A 1 771 ? 10.050 -13.027 -21.125 1.00 102.85 ? 771 HIS A N 1 ATOM 5452 C CA . HIS A 1 771 ? 9.777 -12.161 -19.988 1.00 107.06 ? 771 HIS A CA 1 ATOM 5453 C C . HIS A 1 771 ? 11.074 -11.624 -19.403 1.00 94.89 ? 771 HIS A C 1 ATOM 5454 O O . HIS A 1 771 ? 12.158 -11.910 -19.909 1.00 90.60 ? 771 HIS A O 1 ATOM 5455 C CB . HIS A 1 771 ? 8.996 -12.924 -18.915 1.00 107.86 ? 771 HIS A CB 1 ATOM 5456 C CG . HIS A 1 771 ? 7.742 -13.567 -19.421 1.00 100.35 ? 771 HIS A CG 1 ATOM 5457 N ND1 . HIS A 1 771 ? 6.811 -12.889 -20.178 1.00 95.86 ? 771 HIS A ND1 1 ATOM 5458 C CD2 . HIS A 1 771 ? 7.261 -14.824 -19.271 1.00 93.48 ? 771 HIS A CD2 1 ATOM 5459 C CE1 . HIS A 1 771 ? 5.814 -13.701 -20.478 1.00 96.54 ? 771 HIS A CE1 1 ATOM 5460 N NE2 . HIS A 1 771 ? 6.061 -14.881 -19.938 1.00 92.49 ? 771 HIS A NE2 1 ATOM 5461 N N . GLY A 1 772 ? 10.957 -10.841 -18.336 1.00 103.33 ? 772 GLY A N 1 ATOM 5462 C CA . GLY A 1 772 ? 12.121 -10.334 -17.634 1.00 110.31 ? 772 GLY A CA 1 ATOM 5463 C C . GLY A 1 772 ? 12.644 -11.360 -16.649 1.00 107.67 ? 772 GLY A C 1 ATOM 5464 O O . GLY A 1 772 ? 12.223 -12.517 -16.669 1.00 102.97 ? 772 GLY A O 1 ATOM 5465 N N . ASP A 1 773 ? 13.558 -10.940 -15.780 1.00 107.98 ? 773 ASP A N 1 ATOM 5466 C CA . ASP A 1 773 ? 14.123 -11.838 -14.778 1.00 116.23 ? 773 ASP A CA 1 ATOM 5467 C C . ASP A 1 773 ? 13.243 -11.899 -13.532 1.00 117.87 ? 773 ASP A C 1 ATOM 5468 O O . ASP A 1 773 ? 13.563 -12.594 -12.567 1.00 119.51 ? 773 ASP A O 1 ATOM 5469 C CB . ASP A 1 773 ? 15.546 -11.414 -14.402 1.00 121.52 ? 773 ASP A CB 1 ATOM 5470 C CG . ASP A 1 773 ? 16.526 -11.571 -15.552 1.00 126.34 ? 773 ASP A CG 1 ATOM 5471 O OD1 . ASP A 1 773 ? 16.163 -12.201 -16.568 1.00 123.27 ? 773 ASP A OD1 1 ATOM 5472 O OD2 . ASP A 1 773 ? 17.667 -11.073 -15.434 1.00 123.33 ? 773 ASP A OD2 1 ATOM 5473 N N . ASP A 1 774 ? 12.133 -11.166 -13.562 1.00 114.27 ? 774 ASP A N 1 ATOM 5474 C CA . ASP A 1 774 ? 11.204 -11.120 -12.437 1.00 108.63 ? 774 ASP A CA 1 ATOM 5475 C C . ASP A 1 774 ? 10.148 -12.214 -12.539 1.00 108.20 ? 774 ASP A C 1 ATOM 5476 O O . ASP A 1 774 ? 9.368 -12.422 -11.608 1.00 100.97 ? 774 ASP A O 1 ATOM 5477 C CB . ASP A 1 774 ? 10.507 -9.761 -12.373 1.00 101.36 ? 774 ASP A CB 1 ATOM 5478 C CG . ASP A 1 774 ? 11.484 -8.606 -12.340 1.00 112.49 ? 774 ASP A CG 1 ATOM 5479 O OD1 . ASP A 1 774 ? 12.575 -8.729 -12.935 1.00 126.18 ? 774 ASP A OD1 1 ATOM 5480 O OD2 . ASP A 1 774 ? 11.156 -7.572 -11.722 1.00 108.86 ? 774 ASP A OD2 1 ATOM 5481 N N . SER A 1 775 ? 10.126 -12.916 -13.667 1.00 113.08 ? 775 SER A N 1 ATOM 5482 C CA . SER A 1 775 ? 9.093 -13.913 -13.911 1.00 101.05 ? 775 SER A CA 1 ATOM 5483 C C . SER A 1 775 ? 9.342 -15.170 -13.086 1.00 97.03 ? 775 SER A C 1 ATOM 5484 O O . SER A 1 775 ? 10.375 -15.827 -13.225 1.00 100.06 ? 775 SER A O 1 ATOM 5485 C CB . SER A 1 775 ? 9.033 -14.265 -15.399 1.00 95.18 ? 775 SER A CB 1 ATOM 5486 O OG . SER A 1 775 ? 8.063 -15.265 -15.653 1.00 87.84 ? 775 SER A OG 1 ATOM 5487 N N . LYS A 1 776 ? 8.378 -15.500 -12.234 1.00 86.29 ? 776 LYS A N 1 ATOM 5488 C CA . LYS A 1 776 ? 8.454 -16.691 -11.401 1.00 88.64 ? 776 LYS A CA 1 ATOM 5489 C C . LYS A 1 776 ? 7.201 -17.524 -11.634 1.00 75.91 ? 776 LYS A C 1 ATOM 5490 O O . LYS A 1 776 ? 6.132 -16.980 -11.906 1.00 72.57 ? 776 LYS A O 1 ATOM 5491 C CB . LYS A 1 776 ? 8.576 -16.313 -9.923 1.00 96.32 ? 776 LYS A CB 1 ATOM 5492 C CG . LYS A 1 776 ? 9.695 -15.324 -9.611 1.00 96.94 ? 776 LYS A CG 1 ATOM 5493 C CD . LYS A 1 776 ? 11.055 -15.829 -10.076 1.00 102.40 ? 776 LYS A CD 1 ATOM 5494 C CE . LYS A 1 776 ? 11.479 -17.087 -9.335 1.00 104.89 ? 776 LYS A CE 1 ATOM 5495 N NZ . LYS A 1 776 ? 12.816 -17.567 -9.789 1.00 109.47 ? 776 LYS A NZ 1 ATOM 5496 N N . ALA A 1 777 ? 7.333 -18.841 -11.525 1.00 72.06 ? 777 ALA A N 1 ATOM 5497 C CA . ALA A 1 777 ? 6.237 -19.741 -11.868 1.00 68.64 ? 777 ALA A CA 1 ATOM 5498 C C . ALA A 1 777 ? 5.757 -20.570 -10.680 1.00 68.30 ? 777 ALA A C 1 ATOM 5499 O O . ALA A 1 777 ? 6.561 -21.178 -9.975 1.00 71.77 ? 777 ALA A O 1 ATOM 5500 C CB . ALA A 1 777 ? 6.656 -20.656 -13.004 1.00 70.24 ? 777 ALA A CB 1 ATOM 5501 N N . VAL A 1 778 ? 4.443 -20.592 -10.469 1.00 62.11 ? 778 VAL A N 1 ATOM 5502 C CA . VAL A 1 778 ? 3.843 -21.444 -9.445 1.00 59.44 ? 778 VAL A CA 1 ATOM 5503 C C . VAL A 1 778 ? 2.799 -22.365 -10.074 1.00 61.71 ? 778 VAL A C 1 ATOM 5504 O O . VAL A 1 778 ? 2.068 -21.958 -10.977 1.00 61.97 ? 778 VAL A O 1 ATOM 5505 C CB . VAL A 1 778 ? 3.173 -20.620 -8.329 1.00 54.52 ? 778 VAL A CB 1 ATOM 5506 C CG1 . VAL A 1 778 ? 3.052 -21.448 -7.070 1.00 49.43 ? 778 VAL A CG1 1 ATOM 5507 C CG2 . VAL A 1 778 ? 3.970 -19.372 -8.042 1.00 57.64 ? 778 VAL A CG2 1 ATOM 5508 N N . LEU A 1 779 ? 2.728 -23.604 -9.596 1.00 67.99 ? 779 LEU A N 1 ATOM 5509 C CA . LEU A 1 779 ? 1.774 -24.573 -10.128 1.00 61.27 ? 779 LEU A CA 1 ATOM 5510 C C . LEU A 1 779 ? 0.715 -24.912 -9.081 1.00 58.92 ? 779 LEU A C 1 ATOM 5511 O O . LEU A 1 779 ? 0.998 -25.582 -8.089 1.00 65.12 ? 779 LEU A O 1 ATOM 5512 C CB . LEU A 1 779 ? 2.505 -25.840 -10.586 1.00 62.57 ? 779 LEU A CB 1 ATOM 5513 C CG . LEU A 1 779 ? 1.751 -26.853 -11.449 1.00 71.97 ? 779 LEU A CG 1 ATOM 5514 C CD1 . LEU A 1 779 ? 1.239 -26.204 -12.723 1.00 80.16 ? 779 LEU A CD1 1 ATOM 5515 C CD2 . LEU A 1 779 ? 2.648 -28.034 -11.778 1.00 77.64 ? 779 LEU A CD2 1 ATOM 5516 N N . LEU A 1 780 ? -0.509 -24.449 -9.315 1.00 61.86 ? 780 LEU A N 1 ATOM 5517 C CA . LEU A 1 780 ? -1.598 -24.625 -8.360 1.00 66.67 ? 780 LEU A CA 1 ATOM 5518 C C . LEU A 1 780 ? -2.381 -25.907 -8.648 1.00 75.28 ? 780 LEU A C 1 ATOM 5519 O O . LEU A 1 780 ? -2.644 -26.231 -9.805 1.00 82.61 ? 780 LEU A O 1 ATOM 5520 C CB . LEU A 1 780 ? -2.522 -23.405 -8.387 1.00 62.34 ? 780 LEU A CB 1 ATOM 5521 C CG . LEU A 1 780 ? -1.858 -22.043 -8.170 1.00 60.24 ? 780 LEU A CG 1 ATOM 5522 C CD1 . LEU A 1 780 ? -2.882 -20.920 -8.184 1.00 55.09 ? 780 LEU A CD1 1 ATOM 5523 C CD2 . LEU A 1 780 ? -1.085 -22.035 -6.866 1.00 70.69 ? 780 LEU A CD2 1 ATOM 5524 N N . PHE A 1 781 ? -2.753 -26.631 -7.596 1.00 75.93 ? 781 PHE A N 1 ATOM 5525 C CA . PHE A 1 781 ? -3.386 -27.941 -7.754 1.00 76.41 ? 781 PHE A CA 1 ATOM 5526 C C . PHE A 1 781 ? -4.820 -27.976 -7.227 1.00 76.19 ? 781 PHE A C 1 ATOM 5527 O O . PHE A 1 781 ? -5.172 -27.220 -6.323 1.00 77.46 ? 781 PHE A O 1 ATOM 5528 C CB . PHE A 1 781 ? -2.542 -29.021 -7.066 1.00 80.79 ? 781 PHE A CB 1 ATOM 5529 C CG . PHE A 1 781 ? -1.427 -29.559 -7.922 1.00 79.20 ? 781 PHE A CG 1 ATOM 5530 C CD1 . PHE A 1 781 ? -1.437 -30.879 -8.343 1.00 78.47 ? 781 PHE A CD1 1 ATOM 5531 C CD2 . PHE A 1 781 ? -0.375 -28.746 -8.312 1.00 69.49 ? 781 PHE A CD2 1 ATOM 5532 C CE1 . PHE A 1 781 ? -0.416 -31.380 -9.130 1.00 73.86 ? 781 PHE A CE1 1 ATOM 5533 C CE2 . PHE A 1 781 ? 0.648 -29.242 -9.100 1.00 62.15 ? 781 PHE A CE2 1 ATOM 5534 C CZ . PHE A 1 781 ? 0.627 -30.560 -9.510 1.00 64.71 ? 781 PHE A CZ 1 ATOM 5535 N N . PRO A 1 782 ? -5.658 -28.854 -7.806 1.00 79.68 ? 782 PRO A N 1 ATOM 5536 C CA . PRO A 1 782 ? -7.037 -29.054 -7.346 1.00 83.26 ? 782 PRO A CA 1 ATOM 5537 C C . PRO A 1 782 ? -7.102 -29.422 -5.866 1.00 81.43 ? 782 PRO A C 1 ATOM 5538 O O . PRO A 1 782 ? -8.065 -29.067 -5.185 1.00 73.13 ? 782 PRO A O 1 ATOM 5539 C CB . PRO A 1 782 ? -7.516 -30.227 -8.203 1.00 86.79 ? 782 PRO A CB 1 ATOM 5540 C CG . PRO A 1 782 ? -6.730 -30.104 -9.461 1.00 84.57 ? 782 PRO A CG 1 ATOM 5541 C CD . PRO A 1 782 ? -5.375 -29.608 -9.041 1.00 77.70 ? 782 PRO A CD 1 ATOM 5542 N N . ASN A 1 783 ? -6.083 -30.129 -5.384 1.00 91.82 ? 783 ASN A N 1 ATOM 5543 C CA . ASN A 1 783 ? -5.975 -30.483 -3.973 1.00 95.27 ? 783 ASN A CA 1 ATOM 5544 C C . ASN A 1 783 ? -5.884 -29.257 -3.077 1.00 89.09 ? 783 ASN A C 1 ATOM 5545 O O . ASN A 1 783 ? -6.335 -29.274 -1.932 1.00 89.60 ? 783 ASN A O 1 ATOM 5546 C CB . ASN A 1 783 ? -4.725 -31.333 -3.731 1.00 94.19 ? 783 ASN A CB 1 ATOM 5547 C CG . ASN A 1 783 ? -4.783 -32.677 -4.422 1.00 103.16 ? 783 ASN A CG 1 ATOM 5548 O OD1 . ASN A 1 783 ? -5.464 -32.845 -5.433 1.00 109.05 ? 783 ASN A OD1 1 ATOM 5549 N ND2 . ASN A 1 783 ? -4.061 -33.649 -3.873 1.00 102.95 ? 783 ASN A ND2 1 ATOM 5550 N N . GLY A 1 784 ? -5.293 -28.194 -3.610 1.00 82.56 ? 784 GLY A N 1 ATOM 5551 C CA . GLY A 1 784 ? -4.901 -27.053 -2.808 1.00 76.62 ? 784 GLY A CA 1 ATOM 5552 C C . GLY A 1 784 ? -3.392 -27.041 -2.682 1.00 81.29 ? 784 GLY A C 1 ATOM 5553 O O . GLY A 1 784 ? -2.800 -26.088 -2.177 1.00 86.36 ? 784 GLY A O 1 ATOM 5554 N N . THR A 1 785 ? -2.773 -28.120 -3.151 1.00 78.81 ? 785 THR A N 1 ATOM 5555 C CA . THR A 1 785 ? -1.324 -28.241 -3.160 1.00 79.68 ? 785 THR A CA 1 ATOM 5556 C C . THR A 1 785 ? -0.716 -27.141 -4.021 1.00 75.56 ? 785 THR A C 1 ATOM 5557 O O . THR A 1 785 ? -1.233 -26.818 -5.089 1.00 77.94 ? 785 THR A O 1 ATOM 5558 C CB . THR A 1 785 ? -0.891 -29.614 -3.705 1.00 81.98 ? 785 THR A CB 1 ATOM 5559 O OG1 . THR A 1 785 ? -1.549 -30.651 -2.967 1.00 86.71 ? 785 THR A OG1 1 ATOM 5560 C CG2 . THR A 1 785 ? 0.614 -29.791 -3.588 1.00 79.52 ? 785 THR A CG2 1 ATOM 5561 N N . VAL A 1 786 ? 0.376 -26.554 -3.545 1.00 72.34 ? 786 VAL A N 1 ATOM 5562 C CA . VAL A 1 786 ? 1.065 -25.508 -4.287 1.00 73.06 ? 786 VAL A CA 1 ATOM 5563 C C . VAL A 1 786 ? 2.520 -25.913 -4.529 1.00 66.82 ? 786 VAL A C 1 ATOM 5564 O O . VAL A 1 786 ? 3.253 -26.214 -3.588 1.00 72.22 ? 786 VAL A O 1 ATOM 5565 C CB . VAL A 1 786 ? 0.974 -24.160 -3.549 1.00 70.72 ? 786 VAL A CB 1 ATOM 5566 C CG1 . VAL A 1 786 ? 1.808 -23.108 -4.244 1.00 70.25 ? 786 VAL A CG1 1 ATOM 5567 C CG2 . VAL A 1 786 ? -0.477 -23.711 -3.451 1.00 60.64 ? 786 VAL A CG2 1 ATOM 5568 N N . VAL A 1 787 ? 2.926 -25.936 -5.796 1.00 58.30 ? 787 VAL A N 1 ATOM 5569 C CA . VAL A 1 787 ? 4.239 -26.447 -6.180 1.00 60.03 ? 787 VAL A CA 1 ATOM 5570 C C . VAL A 1 787 ? 4.987 -25.418 -7.036 1.00 57.41 ? 787 VAL A C 1 ATOM 5571 O O . VAL A 1 787 ? 4.386 -24.462 -7.523 1.00 53.77 ? 787 VAL A O 1 ATOM 5572 C CB . VAL A 1 787 ? 4.103 -27.782 -6.964 1.00 63.82 ? 787 VAL A CB 1 ATOM 5573 C CG1 . VAL A 1 787 ? 5.397 -28.572 -6.918 1.00 67.77 ? 787 VAL A CG1 1 ATOM 5574 C CG2 . VAL A 1 787 ? 2.966 -28.627 -6.401 1.00 61.12 ? 787 VAL A CG2 1 ATOM 5575 N N . THR A 1 788 ? 6.298 -25.605 -7.195 1.00 70.15 ? 788 THR A N 1 ATOM 5576 C CA . THR A 1 788 ? 7.117 -24.764 -8.071 1.00 72.27 ? 788 THR A CA 1 ATOM 5577 C C . THR A 1 788 ? 7.873 -25.616 -9.089 1.00 68.75 ? 788 THR A C 1 ATOM 5578 O O . THR A 1 788 ? 8.421 -26.665 -8.749 1.00 72.10 ? 788 THR A O 1 ATOM 5579 C CB . THR A 1 788 ? 8.141 -23.931 -7.272 1.00 73.74 ? 788 THR A CB 1 ATOM 5580 O OG1 . THR A 1 788 ? 7.468 -23.186 -6.250 1.00 88.93 ? 788 THR A OG1 1 ATOM 5581 C CG2 . THR A 1 788 ? 8.888 -22.966 -8.190 1.00 53.48 ? 788 THR A CG2 1 ATOM 5582 N N . LEU A 1 789 ? 7.901 -25.165 -10.339 1.00 65.59 ? 789 LEU A N 1 ATOM 5583 C CA . LEU A 1 789 ? 8.598 -25.894 -11.391 1.00 71.57 ? 789 LEU A CA 1 ATOM 5584 C C . LEU A 1 789 ? 10.095 -25.609 -11.348 1.00 68.38 ? 789 LEU A C 1 ATOM 5585 O O . LEU A 1 789 ? 10.511 -24.462 -11.190 1.00 65.36 ? 789 LEU A O 1 ATOM 5586 C CB . LEU A 1 789 ? 8.032 -25.530 -12.765 1.00 78.49 ? 789 LEU A CB 1 ATOM 5587 C CG . LEU A 1 789 ? 6.546 -25.819 -12.982 1.00 86.31 ? 789 LEU A CG 1 ATOM 5588 C CD1 . LEU A 1 789 ? 6.106 -25.393 -14.376 1.00 96.00 ? 789 LEU A CD1 1 ATOM 5589 C CD2 . LEU A 1 789 ? 6.243 -27.291 -12.745 1.00 85.78 ? 789 LEU A CD2 1 ATOM 5590 N N . LEU A 1 790 ? 10.899 -26.658 -11.487 1.00 66.28 ? 790 LEU A N 1 ATOM 5591 C CA . LEU A 1 790 ? 12.349 -26.517 -11.515 1.00 56.77 ? 790 LEU A CA 1 ATOM 5592 C C . LEU A 1 790 ? 12.816 -26.409 -12.962 1.00 51.84 ? 790 LEU A C 1 ATOM 5593 O O . LEU A 1 790 ? 12.746 -27.382 -13.712 1.00 52.30 ? 790 LEU A O 1 ATOM 5594 C CB . LEU A 1 790 ? 13.003 -27.730 -10.849 1.00 72.06 ? 790 LEU A CB 1 ATOM 5595 C CG . LEU A 1 790 ? 12.422 -28.173 -9.501 1.00 91.68 ? 790 LEU A CG 1 ATOM 5596 C CD1 . LEU A 1 790 ? 12.906 -29.570 -9.136 1.00 95.13 ? 790 LEU A CD1 1 ATOM 5597 C CD2 . LEU A 1 790 ? 12.760 -27.182 -8.391 1.00 90.47 ? 790 LEU A CD2 1 ATOM 5598 N N . GLY A 1 791 ? 13.298 -25.230 -13.350 1.00 53.04 ? 791 GLY A N 1 ATOM 5599 C CA . GLY A 1 791 ? 13.726 -24.996 -14.720 1.00 50.00 ? 791 GLY A CA 1 ATOM 5600 C C . GLY A 1 791 ? 13.991 -23.533 -15.038 1.00 42.54 ? 791 GLY A C 1 ATOM 5601 O O . GLY A 1 791 ? 13.151 -22.665 -14.784 1.00 40.67 ? 791 GLY A O 1 ATOM 5602 N N . THR B 2 7 ? -50.706 9.865 13.516 1.00 83.21 ? 29 THR B N 1 ATOM 5603 C CA . THR B 2 7 ? -51.807 10.665 12.992 1.00 95.01 ? 29 THR B CA 1 ATOM 5604 C C . THR B 2 7 ? -53.123 9.898 13.060 1.00 111.90 ? 29 THR B C 1 ATOM 5605 O O . THR B 2 7 ? -53.131 8.671 13.160 1.00 113.41 ? 29 THR B O 1 ATOM 5606 C CB . THR B 2 7 ? -51.516 11.091 11.560 1.00 83.51 ? 29 THR B CB 1 ATOM 5607 N N . PRO B 2 8 ? -54.233 10.628 13.006 1.00 121.72 ? 30 PRO B N 1 ATOM 5608 C CA . PRO B 2 8 ? -55.554 10.013 12.969 1.00 119.30 ? 30 PRO B CA 1 ATOM 5609 C C . PRO B 2 8 ? -56.052 10.013 11.529 1.00 124.49 ? 30 PRO B C 1 ATOM 5610 O O . PRO B 2 8 ? -56.363 11.066 10.974 1.00 116.88 ? 30 PRO B O 1 ATOM 5611 C CB . PRO B 2 8 ? -56.519 10.770 13.868 1.00 108.03 ? 30 PRO B CB 1 ATOM 5612 N N . LEU B 2 9 ? -56.127 8.828 10.930 1.00 129.40 ? 31 LEU B N 1 ATOM 5613 C CA . LEU B 2 9 ? -56.441 8.707 9.509 1.00 121.82 ? 31 LEU B CA 1 ATOM 5614 C C . LEU B 2 9 ? -57.942 8.703 9.223 1.00 127.21 ? 31 LEU B C 1 ATOM 5615 O O . LEU B 2 9 ? -58.761 8.882 10.125 1.00 123.90 ? 31 LEU B O 1 ATOM 5616 C CB . LEU B 2 9 ? -55.777 7.468 8.918 1.00 109.32 ? 31 LEU B CB 1 ATOM 5617 N N . PHE B 2 10 ? -58.287 8.493 7.956 1.00 126.22 ? 32 PHE B N 1 ATOM 5618 C CA . PHE B 2 10 ? -59.667 8.572 7.492 1.00 121.54 ? 32 PHE B CA 1 ATOM 5619 C C . PHE B 2 10 ? -59.872 7.529 6.398 1.00 118.91 ? 32 PHE B C 1 ATOM 5620 O O . PHE B 2 10 ? -58.999 7.334 5.552 1.00 120.63 ? 32 PHE B O 1 ATOM 5621 C CB . PHE B 2 10 ? -59.925 9.977 6.945 1.00 113.23 ? 32 PHE B CB 1 ATOM 5622 C CG . PHE B 2 10 ? -61.376 10.349 6.842 1.00 107.32 ? 32 PHE B CG 1 ATOM 5623 C CD1 . PHE B 2 10 ? -62.120 10.616 7.978 1.00 112.30 ? 32 PHE B CD1 1 ATOM 5624 C CD2 . PHE B 2 10 ? -61.983 10.476 5.604 1.00 109.36 ? 32 PHE B CD2 1 ATOM 5625 C CE1 . PHE B 2 10 ? -63.453 10.975 7.882 1.00 115.68 ? 32 PHE B CE1 1 ATOM 5626 C CE2 . PHE B 2 10 ? -63.315 10.833 5.500 1.00 106.00 ? 32 PHE B CE2 1 ATOM 5627 C CZ . PHE B 2 10 ? -64.051 11.084 6.640 1.00 106.51 ? 32 PHE B CZ 1 ATOM 5628 N N . PHE B 2 11 ? -61.019 6.856 6.413 1.00 117.72 ? 33 PHE B N 1 ATOM 5629 C CA . PHE B 2 11 ? -61.290 5.806 5.434 1.00 122.57 ? 33 PHE B CA 1 ATOM 5630 C C . PHE B 2 11 ? -61.750 6.391 4.101 1.00 115.03 ? 33 PHE B C 1 ATOM 5631 O O . PHE B 2 11 ? -61.798 5.694 3.088 1.00 112.98 ? 33 PHE B O 1 ATOM 5632 C CB . PHE B 2 11 ? -62.319 4.805 5.972 1.00 129.65 ? 33 PHE B CB 1 ATOM 5633 C CG . PHE B 2 11 ? -62.526 3.610 5.080 1.00 141.48 ? 33 PHE B CG 1 ATOM 5634 C CD1 . PHE B 2 11 ? -61.502 2.700 4.869 1.00 140.28 ? 33 PHE B CD1 1 ATOM 5635 C CD2 . PHE B 2 11 ? -63.745 3.395 4.456 1.00 139.95 ? 33 PHE B CD2 1 ATOM 5636 C CE1 . PHE B 2 11 ? -61.687 1.601 4.049 1.00 140.64 ? 33 PHE B CE1 1 ATOM 5637 C CE2 . PHE B 2 11 ? -63.937 2.296 3.635 1.00 141.39 ? 33 PHE B CE2 1 ATOM 5638 C CZ . PHE B 2 11 ? -62.906 1.398 3.432 1.00 140.59 ? 33 PHE B CZ 1 ATOM 5639 N N . GLY B 2 12 ? -62.081 7.678 4.107 1.00 109.19 ? 34 GLY B N 1 ATOM 5640 C CA . GLY B 2 12 ? -62.469 8.370 2.892 1.00 101.54 ? 34 GLY B CA 1 ATOM 5641 C C . GLY B 2 12 ? -63.968 8.419 2.674 1.00 98.63 ? 34 GLY B C 1 ATOM 5642 O O . GLY B 2 12 ? -64.451 9.133 1.796 1.00 86.04 ? 34 GLY B O 1 ATOM 5643 N N . ALA B 2 13 ? -64.709 7.662 3.475 1.00 101.78 ? 35 ALA B N 1 ATOM 5644 C CA . ALA B 2 13 ? -66.152 7.579 3.300 1.00 96.20 ? 35 ALA B CA 1 ATOM 5645 C C . ALA B 2 13 ? -66.925 7.590 4.616 1.00 101.03 ? 35 ALA B C 1 ATOM 5646 O O . ALA B 2 13 ? -66.642 6.803 5.519 1.00 102.47 ? 35 ALA B O 1 ATOM 5647 C CB . ALA B 2 13 ? -66.510 6.342 2.486 1.00 95.99 ? 35 ALA B CB 1 ATOM 5648 N N . LYS B 2 14 ? -67.899 8.490 4.713 1.00 103.55 ? 36 LYS B N 1 ATOM 5649 C CA . LYS B 2 14 ? -68.888 8.444 5.783 1.00 101.63 ? 36 LYS B CA 1 ATOM 5650 C C . LYS B 2 14 ? -70.277 8.532 5.160 1.00 98.77 ? 36 LYS B C 1 ATOM 5651 O O . LYS B 2 14 ? -70.489 9.293 4.216 1.00 98.57 ? 36 LYS B O 1 ATOM 5652 C CB . LYS B 2 14 ? -68.681 9.589 6.778 1.00 97.92 ? 36 LYS B CB 1 ATOM 5653 C CG . LYS B 2 14 ? -67.335 9.564 7.490 1.00 103.09 ? 36 LYS B CG 1 ATOM 5654 C CD . LYS B 2 14 ? -67.304 10.507 8.688 1.00 108.29 ? 36 LYS B CD 1 ATOM 5655 C CE . LYS B 2 14 ? -67.514 11.957 8.278 1.00 104.33 ? 36 LYS B CE 1 ATOM 5656 N NZ . LYS B 2 14 ? -67.379 12.889 9.435 1.00 104.45 ? 36 LYS B NZ 1 ATOM 5657 N N . PRO B 2 15 ? -71.228 7.741 5.677 1.00 95.49 ? 37 PRO B N 1 ATOM 5658 C CA . PRO B 2 15 ? -72.597 7.745 5.148 1.00 90.43 ? 37 PRO B CA 1 ATOM 5659 C C . PRO B 2 15 ? -73.392 8.970 5.581 1.00 86.13 ? 37 PRO B C 1 ATOM 5660 O O . PRO B 2 15 ? -73.240 9.422 6.715 1.00 93.66 ? 37 PRO B O 1 ATOM 5661 C CB . PRO B 2 15 ? -73.206 6.480 5.753 1.00 87.98 ? 37 PRO B CB 1 ATOM 5662 C CG . PRO B 2 15 ? -72.449 6.272 7.018 1.00 97.66 ? 37 PRO B CG 1 ATOM 5663 C CD . PRO B 2 15 ? -71.048 6.735 6.739 1.00 90.70 ? 37 PRO B CD 1 ATOM 5664 N N . LEU B 2 16 ? -74.216 9.505 4.686 1.00 80.45 ? 38 LEU B N 1 ATOM 5665 C CA . LEU B 2 16 ? -75.119 10.599 5.029 1.00 83.94 ? 38 LEU B CA 1 ATOM 5666 C C . LEU B 2 16 ? -76.491 10.397 4.387 1.00 96.61 ? 38 LEU B C 1 ATOM 5667 O O . LEU B 2 16 ? -76.602 10.253 3.168 1.00 101.90 ? 38 LEU B O 1 ATOM 5668 C CB . LEU B 2 16 ? -74.518 11.950 4.620 1.00 79.33 ? 38 LEU B CB 1 ATOM 5669 C CG . LEU B 2 16 ? -73.334 12.441 5.462 1.00 86.18 ? 38 LEU B CG 1 ATOM 5670 C CD1 . LEU B 2 16 ? -72.727 13.709 4.890 1.00 82.29 ? 38 LEU B CD1 1 ATOM 5671 C CD2 . LEU B 2 16 ? -73.749 12.659 6.909 1.00 99.94 ? 38 LEU B CD2 1 ATOM 5672 N N . SER B 2 17 ? -77.531 10.378 5.213 1.00 101.18 ? 39 SER B N 1 ATOM 5673 C CA . SER B 2 17 ? -78.892 10.208 4.718 1.00 104.85 ? 39 SER B CA 1 ATOM 5674 C C . SER B 2 17 ? -79.471 11.515 4.175 1.00 106.09 ? 39 SER B C 1 ATOM 5675 O O . SER B 2 17 ? -80.206 11.512 3.187 1.00 103.66 ? 39 SER B O 1 ATOM 5676 C CB . SER B 2 17 ? -79.797 9.632 5.812 1.00 108.02 ? 39 SER B CB 1 ATOM 5677 O OG . SER B 2 17 ? -81.088 9.331 5.304 1.00 111.30 ? 39 SER B OG 1 ATOM 5678 N N . ASP B 2 18 ? -79.136 12.631 4.818 1.00 105.55 ? 40 ASP B N 1 ATOM 5679 C CA . ASP B 2 18 ? -79.699 13.925 4.441 1.00 106.06 ? 40 ASP B CA 1 ATOM 5680 C C . ASP B 2 18 ? -78.638 14.895 3.928 1.00 106.05 ? 40 ASP B C 1 ATOM 5681 O O . ASP B 2 18 ? -77.469 14.805 4.301 1.00 103.66 ? 40 ASP B O 1 ATOM 5682 C CB . ASP B 2 18 ? -80.442 14.547 5.625 1.00 115.60 ? 40 ASP B CB 1 ATOM 5683 C CG . ASP B 2 18 ? -81.789 15.121 5.229 1.00 132.50 ? 40 ASP B CG 1 ATOM 5684 O OD1 . ASP B 2 18 ? -82.405 14.591 4.280 1.00 139.09 ? 40 ASP B OD1 1 ATOM 5685 O OD2 . ASP B 2 18 ? -82.235 16.097 5.870 1.00 136.66 ? 40 ASP B OD2 1 ATOM 5686 N N . VAL B 2 19 ? -79.063 15.827 3.078 1.00 107.19 ? 41 VAL B N 1 ATOM 5687 C CA . VAL B 2 19 ? -78.161 16.800 2.463 1.00 105.38 ? 41 VAL B CA 1 ATOM 5688 C C . VAL B 2 19 ? -77.764 17.924 3.419 1.00 100.81 ? 41 VAL B C 1 ATOM 5689 O O . VAL B 2 19 ? -76.699 18.526 3.274 1.00 94.77 ? 41 VAL B O 1 ATOM 5690 C CB . VAL B 2 19 ? -78.783 17.417 1.190 1.00 100.99 ? 41 VAL B CB 1 ATOM 5691 C CG1 . VAL B 2 19 ? -78.002 16.998 -0.047 1.00 92.60 ? 41 VAL B CG1 1 ATOM 5692 C CG2 . VAL B 2 19 ? -80.250 17.021 1.065 1.00 104.21 ? 41 VAL B CG2 1 ATOM 5693 N N . SER B 2 20 ? -78.625 18.204 4.393 1.00 105.35 ? 42 SER B N 1 ATOM 5694 C CA . SER B 2 20 ? -78.373 19.264 5.361 1.00 97.32 ? 42 SER B CA 1 ATOM 5695 C C . SER B 2 20 ? -77.182 18.929 6.253 1.00 92.97 ? 42 SER B C 1 ATOM 5696 O O . SER B 2 20 ? -76.503 19.820 6.762 1.00 90.62 ? 42 SER B O 1 ATOM 5697 C CB . SER B 2 20 ? -79.616 19.505 6.220 1.00 105.96 ? 42 SER B CB 1 ATOM 5698 O OG . SER B 2 20 ? -79.949 18.348 6.967 1.00 116.64 ? 42 SER B OG 1 ATOM 5699 N N . LEU B 2 21 ? -76.933 17.636 6.429 1.00 97.07 ? 43 LEU B N 1 ATOM 5700 C CA . LEU B 2 21 ? -75.863 17.166 7.302 1.00 99.27 ? 43 LEU B CA 1 ATOM 5701 C C . LEU B 2 21 ? -74.482 17.291 6.657 1.00 94.00 ? 43 LEU B C 1 ATOM 5702 O O . LEU B 2 21 ? -73.478 17.448 7.355 1.00 91.49 ? 43 LEU B O 1 ATOM 5703 C CB . LEU B 2 21 ? -76.125 15.717 7.723 1.00 106.15 ? 43 LEU B CB 1 ATOM 5704 C CG . LEU B 2 21 ? -77.460 15.469 8.430 1.00 102.01 ? 43 LEU B CG 1 ATOM 5705 C CD1 . LEU B 2 21 ? -77.661 13.989 8.728 1.00 104.31 ? 43 LEU B CD1 1 ATOM 5706 C CD2 . LEU B 2 21 ? -77.541 16.291 9.705 1.00 99.08 ? 43 LEU B CD2 1 ATOM 5707 N N . ILE B 2 22 ? -74.438 17.219 5.329 1.00 87.85 ? 44 ILE B N 1 ATOM 5708 C CA . ILE B 2 22 ? -73.187 17.349 4.588 1.00 81.36 ? 44 ILE B CA 1 ATOM 5709 C C . ILE B 2 22 ? -72.578 18.732 4.796 1.00 82.74 ? 44 ILE B C 1 ATOM 5710 O O . ILE B 2 22 ? -71.371 18.868 4.994 1.00 88.38 ? 44 ILE B O 1 ATOM 5711 C CB . ILE B 2 22 ? -73.394 17.127 3.072 1.00 82.38 ? 44 ILE B CB 1 ATOM 5712 C CG1 . ILE B 2 22 ? -74.414 16.016 2.818 1.00 92.92 ? 44 ILE B CG1 1 ATOM 5713 C CG2 . ILE B 2 22 ? -72.070 16.816 2.389 1.00 81.58 ? 44 ILE B CG2 1 ATOM 5714 C CD1 . ILE B 2 22 ? -74.539 15.630 1.359 1.00 92.44 ? 44 ILE B CD1 1 ATOM 5715 N N . ILE B 2 23 ? -73.428 19.753 4.753 1.00 73.59 ? 45 ILE B N 1 ATOM 5716 C CA . ILE B 2 23 ? -72.994 21.134 4.926 1.00 76.79 ? 45 ILE B CA 1 ATOM 5717 C C . ILE B 2 23 ? -72.521 21.388 6.358 1.00 88.24 ? 45 ILE B C 1 ATOM 5718 O O . ILE B 2 23 ? -71.537 22.096 6.584 1.00 85.20 ? 45 ILE B O 1 ATOM 5719 C CB . ILE B 2 23 ? -74.128 22.119 4.573 1.00 59.01 ? 45 ILE B CB 1 ATOM 5720 C CG1 . ILE B 2 23 ? -74.783 21.723 3.250 1.00 61.80 ? 45 ILE B CG1 1 ATOM 5721 C CG2 . ILE B 2 23 ? -73.607 23.544 4.503 1.00 61.26 ? 45 ILE B CG2 1 ATOM 5722 C CD1 . ILE B 2 23 ? -75.831 22.704 2.772 1.00 70.32 ? 45 ILE B CD1 1 ATOM 5723 N N . THR B 2 24 ? -73.223 20.796 7.319 1.00 89.08 ? 46 THR B N 1 ATOM 5724 C CA . THR B 2 24 ? -72.899 20.970 8.731 1.00 83.26 ? 46 THR B CA 1 ATOM 5725 C C . THR B 2 24 ? -71.705 20.122 9.161 1.00 86.04 ? 46 THR B C 1 ATOM 5726 O O . THR B 2 24 ? -71.127 20.353 10.223 1.00 88.69 ? 46 THR B O 1 ATOM 5727 C CB . THR B 2 24 ? -74.101 20.627 9.632 1.00 81.95 ? 46 THR B CB 1 ATOM 5728 O OG1 . THR B 2 24 ? -74.482 19.261 9.423 1.00 82.96 ? 46 THR B OG1 1 ATOM 5729 C CG2 . THR B 2 24 ? -75.280 21.532 9.317 1.00 81.49 ? 46 THR B CG2 1 ATOM 5730 N N . GLU B 2 25 ? -71.343 19.141 8.340 1.00 87.35 ? 47 GLU B N 1 ATOM 5731 C CA . GLU B 2 25 ? -70.201 18.283 8.637 1.00 89.08 ? 47 GLU B CA 1 ATOM 5732 C C . GLU B 2 25 ? -68.920 19.095 8.761 1.00 92.46 ? 47 GLU B C 1 ATOM 5733 O O . GLU B 2 25 ? -68.513 19.767 7.814 1.00 91.11 ? 47 GLU B O 1 ATOM 5734 C CB . GLU B 2 25 ? -70.035 17.200 7.569 1.00 94.08 ? 47 GLU B CB 1 ATOM 5735 C CG . GLU B 2 25 ? -70.644 15.866 7.953 1.00 95.09 ? 47 GLU B CG 1 ATOM 5736 C CD . GLU B 2 25 ? -70.008 15.279 9.196 1.00 96.44 ? 47 GLU B CD 1 ATOM 5737 O OE1 . GLU B 2 25 ? -68.770 15.374 9.335 1.00 98.01 ? 47 GLU B OE1 1 ATOM 5738 O OE2 . GLU B 2 25 ? -70.748 14.729 10.038 1.00 91.84 ? 47 GLU B OE2 1 ATOM 5739 N N . PRO B 2 26 ? -68.281 19.032 9.939 1.00 101.24 ? 48 PRO B N 1 ATOM 5740 C CA . PRO B 2 26 ? -67.061 19.792 10.227 1.00 103.91 ? 48 PRO B CA 1 ATOM 5741 C C . PRO B 2 26 ? -65.933 19.402 9.287 1.00 96.62 ? 48 PRO B C 1 ATOM 5742 O O . PRO B 2 26 ? -65.938 18.291 8.757 1.00 94.58 ? 48 PRO B O 1 ATOM 5743 C CB . PRO B 2 26 ? -66.717 19.374 11.662 1.00 111.53 ? 48 PRO B CB 1 ATOM 5744 C CG . PRO B 2 26 ? -67.399 18.061 11.855 1.00 112.56 ? 48 PRO B CG 1 ATOM 5745 C CD . PRO B 2 26 ? -68.664 18.158 11.061 1.00 100.38 ? 48 PRO B CD 1 ATOM 5746 N N . CYS B 2 27 ? -64.984 20.308 9.082 1.00 96.45 ? 49 CYS B N 1 ATOM 5747 C CA . CYS B 2 27 ? -63.869 20.051 8.180 1.00 110.95 ? 49 CYS B CA 1 ATOM 5748 C C . CYS B 2 27 ? -63.045 18.844 8.629 1.00 111.51 ? 49 CYS B C 1 ATOM 5749 O O . CYS B 2 27 ? -62.686 18.723 9.800 1.00 115.79 ? 49 CYS B O 1 ATOM 5750 C CB . CYS B 2 27 ? -62.982 21.292 8.052 1.00 117.59 ? 49 CYS B CB 1 ATOM 5751 S SG . CYS B 2 27 ? -63.798 22.713 7.281 1.00 139.70 ? 49 CYS B SG 1 ATOM 5752 N N . VAL B 2 28 ? -62.767 17.948 7.686 1.00 104.95 ? 50 VAL B N 1 ATOM 5753 C CA . VAL B 2 28 ? -61.986 16.748 7.960 1.00 106.77 ? 50 VAL B CA 1 ATOM 5754 C C . VAL B 2 28 ? -60.555 17.124 8.336 1.00 114.71 ? 50 VAL B C 1 ATOM 5755 O O . VAL B 2 28 ? -59.940 16.496 9.198 1.00 116.86 ? 50 VAL B O 1 ATOM 5756 C CB . VAL B 2 28 ? -61.972 15.804 6.738 1.00 101.98 ? 50 VAL B CB 1 ATOM 5757 C CG1 . VAL B 2 28 ? -61.240 14.511 7.061 1.00 108.58 ? 50 VAL B CG1 1 ATOM 5758 C CG2 . VAL B 2 28 ? -63.390 15.508 6.281 1.00 97.55 ? 50 VAL B CG2 1 ATOM 5759 N N . SER B 2 29 ? -60.042 18.167 7.689 1.00 115.25 ? 51 SER B N 1 ATOM 5760 C CA . SER B 2 29 ? -58.678 18.640 7.910 1.00 115.74 ? 51 SER B CA 1 ATOM 5761 C C . SER B 2 29 ? -58.459 19.143 9.337 1.00 115.69 ? 51 SER B C 1 ATOM 5762 O O . SER B 2 29 ? -57.345 19.088 9.858 1.00 117.18 ? 51 SER B O 1 ATOM 5763 C CB . SER B 2 29 ? -58.334 19.743 6.905 1.00 107.63 ? 51 SER B CB 1 ATOM 5764 O OG . SER B 2 29 ? -56.986 20.163 7.033 1.00 101.57 ? 51 SER B OG 1 ATOM 5765 N N . SER B 2 30 ? -59.525 19.628 9.965 1.00 115.03 ? 52 SER B N 1 ATOM 5766 C CA . SER B 2 30 ? -59.436 20.172 11.317 1.00 118.51 ? 52 SER B CA 1 ATOM 5767 C C . SER B 2 30 ? -59.362 19.080 12.383 1.00 127.65 ? 52 SER B C 1 ATOM 5768 O O . SER B 2 30 ? -58.594 19.184 13.339 1.00 136.53 ? 52 SER B O 1 ATOM 5769 C CB . SER B 2 30 ? -60.624 21.095 11.598 1.00 114.43 ? 52 SER B CB 1 ATOM 5770 O OG . SER B 2 30 ? -61.851 20.396 11.484 1.00 119.24 ? 52 SER B OG 1 ATOM 5771 N N . VAL B 2 31 ? -60.168 18.036 12.213 1.00 123.66 ? 53 VAL B N 1 ATOM 5772 C CA . VAL B 2 31 ? -60.223 16.937 13.171 1.00 121.57 ? 53 VAL B CA 1 ATOM 5773 C C . VAL B 2 31 ? -59.021 16.000 13.045 1.00 130.05 ? 53 VAL B C 1 ATOM 5774 O O . VAL B 2 31 ? -58.425 15.595 14.045 1.00 131.36 ? 53 VAL B O 1 ATOM 5775 C CB . VAL B 2 31 ? -61.519 16.117 13.001 1.00 117.61 ? 53 VAL B CB 1 ATOM 5776 C CG1 . VAL B 2 31 ? -61.551 14.954 13.980 1.00 115.77 ? 53 VAL B CG1 1 ATOM 5777 C CG2 . VAL B 2 31 ? -62.738 17.012 13.183 1.00 124.30 ? 53 VAL B CG2 1 ATOM 5778 N N . TYR B 2 32 ? -58.671 15.663 11.808 1.00 131.90 ? 54 TYR B N 1 ATOM 5779 C CA . TYR B 2 32 ? -57.624 14.684 11.541 1.00 125.12 ? 54 TYR B CA 1 ATOM 5780 C C . TYR B 2 32 ? -56.322 15.344 11.087 1.00 125.17 ? 54 TYR B C 1 ATOM 5781 O O . TYR B 2 32 ? -56.229 16.569 11.012 1.00 127.08 ? 54 TYR B O 1 ATOM 5782 C CB . TYR B 2 32 ? -58.103 13.684 10.485 1.00 122.05 ? 54 TYR B CB 1 ATOM 5783 C CG . TYR B 2 32 ? -59.442 13.048 10.799 1.00 125.17 ? 54 TYR B CG 1 ATOM 5784 C CD1 . TYR B 2 32 ? -59.517 11.835 11.470 1.00 123.61 ? 54 TYR B CD1 1 ATOM 5785 C CD2 . TYR B 2 32 ? -60.630 13.660 10.422 1.00 118.92 ? 54 TYR B CD2 1 ATOM 5786 C CE1 . TYR B 2 32 ? -60.737 11.251 11.757 1.00 119.34 ? 54 TYR B CE1 1 ATOM 5787 C CE2 . TYR B 2 32 ? -61.853 13.085 10.704 1.00 113.22 ? 54 TYR B CE2 1 ATOM 5788 C CZ . TYR B 2 32 ? -61.901 11.882 11.371 1.00 114.54 ? 54 TYR B CZ 1 ATOM 5789 O OH . TYR B 2 32 ? -63.118 11.307 11.654 1.00 118.13 ? 54 TYR B OH 1 ATOM 5790 N N . GLU B 2 33 ? -55.318 14.524 10.790 1.00 131.38 ? 55 GLU B N 1 ATOM 5791 C CA . GLU B 2 33 ? -54.040 15.020 10.287 1.00 129.17 ? 55 GLU B CA 1 ATOM 5792 C C . GLU B 2 33 ? -53.873 14.669 8.812 1.00 127.79 ? 55 GLU B C 1 ATOM 5793 O O . GLU B 2 33 ? -53.823 15.551 7.955 1.00 120.56 ? 55 GLU B O 1 ATOM 5794 C CB . GLU B 2 33 ? -52.884 14.456 11.106 1.00 108.51 ? 55 GLU B CB 1 ATOM 5795 N N . ALA B 2 34 ? -53.788 13.373 8.526 1.00 127.84 ? 56 ALA B N 1 ATOM 5796 C CA . ALA B 2 34 ? -53.676 12.891 7.154 1.00 117.13 ? 56 ALA B CA 1 ATOM 5797 C C . ALA B 2 34 ? -54.826 11.947 6.819 1.00 106.35 ? 56 ALA B C 1 ATOM 5798 O O . ALA B 2 34 ? -55.125 11.024 7.578 1.00 102.26 ? 56 ALA B O 1 ATOM 5799 C CB . ALA B 2 34 ? -52.339 12.201 6.941 1.00 127.59 ? 56 ALA B CB 1 ATOM 5800 N N . TRP B 2 35 ? -55.466 12.180 5.678 1.00 110.31 ? 57 TRP B N 1 ATOM 5801 C CA . TRP B 2 35 ? -56.612 11.377 5.264 1.00 112.51 ? 57 TRP B CA 1 ATOM 5802 C C . TRP B 2 35 ? -56.449 10.799 3.862 1.00 111.21 ? 57 TRP B C 1 ATOM 5803 O O . TRP B 2 35 ? -55.691 11.324 3.046 1.00 108.53 ? 57 TRP B O 1 ATOM 5804 C CB . TRP B 2 35 ? -57.895 12.208 5.327 1.00 107.99 ? 57 TRP B CB 1 ATOM 5805 C CG . TRP B 2 35 ? -57.850 13.456 4.512 1.00 107.75 ? 57 TRP B CG 1 ATOM 5806 C CD1 . TRP B 2 35 ? -58.309 13.624 3.239 1.00 98.40 ? 57 TRP B CD1 1 ATOM 5807 C CD2 . TRP B 2 35 ? -57.317 14.720 4.917 1.00 110.32 ? 57 TRP B CD2 1 ATOM 5808 N NE1 . TRP B 2 35 ? -58.093 14.917 2.825 1.00 101.77 ? 57 TRP B NE1 1 ATOM 5809 C CE2 . TRP B 2 35 ? -57.485 15.610 3.838 1.00 106.19 ? 57 TRP B CE2 1 ATOM 5810 C CE3 . TRP B 2 35 ? -56.712 15.186 6.088 1.00 106.63 ? 57 TRP B CE3 1 ATOM 5811 C CZ2 . TRP B 2 35 ? -57.070 16.937 3.896 1.00 100.20 ? 57 TRP B CZ2 1 ATOM 5812 C CZ3 . TRP B 2 35 ? -56.303 16.503 6.143 1.00 105.44 ? 57 TRP B CZ3 1 ATOM 5813 C CH2 . TRP B 2 35 ? -56.483 17.363 5.055 1.00 99.58 ? 57 TRP B CH2 1 ATOM 5814 N N . ASP B 2 36 ? -57.165 9.712 3.592 1.00 104.28 ? 58 ASP B N 1 ATOM 5815 C CA . ASP B 2 36 ? -57.195 9.132 2.256 1.00 93.36 ? 58 ASP B CA 1 ATOM 5816 C C . ASP B 2 36 ? -58.489 9.502 1.547 1.00 92.32 ? 58 ASP B C 1 ATOM 5817 O O . ASP B 2 36 ? -59.552 9.570 2.164 1.00 90.92 ? 58 ASP B O 1 ATOM 5818 C CB . ASP B 2 36 ? -57.058 7.608 2.315 1.00 84.48 ? 58 ASP B CB 1 ATOM 5819 C CG . ASP B 2 36 ? -55.657 7.162 2.676 1.00 93.74 ? 58 ASP B CG 1 ATOM 5820 O OD1 . ASP B 2 36 ? -54.712 7.954 2.484 1.00 100.93 ? 58 ASP B OD1 1 ATOM 5821 O OD2 . ASP B 2 36 ? -55.501 6.015 3.146 1.00 98.40 ? 58 ASP B OD2 1 ATOM 5822 N N . TYR B 2 37 ? -58.391 9.756 0.247 1.00 83.25 ? 59 TYR B N 1 ATOM 5823 C CA . TYR B 2 37 ? -59.574 9.971 -0.572 1.00 69.71 ? 59 TYR B CA 1 ATOM 5824 C C . TYR B 2 37 ? -60.030 8.638 -1.160 1.00 64.99 ? 59 TYR B C 1 ATOM 5825 O O . TYR B 2 37 ? -59.205 7.813 -1.555 1.00 65.37 ? 59 TYR B O 1 ATOM 5826 C CB . TYR B 2 37 ? -59.278 10.971 -1.693 1.00 66.69 ? 59 TYR B CB 1 ATOM 5827 C CG . TYR B 2 37 ? -58.844 12.340 -1.210 1.00 67.01 ? 59 TYR B CG 1 ATOM 5828 C CD1 . TYR B 2 37 ? -59.780 13.295 -0.839 1.00 69.11 ? 59 TYR B CD1 1 ATOM 5829 C CD2 . TYR B 2 37 ? -57.500 12.680 -1.140 1.00 63.63 ? 59 TYR B CD2 1 ATOM 5830 C CE1 . TYR B 2 37 ? -59.391 14.547 -0.405 1.00 67.84 ? 59 TYR B CE1 1 ATOM 5831 C CE2 . TYR B 2 37 ? -57.101 13.931 -0.707 1.00 64.51 ? 59 TYR B CE2 1 ATOM 5832 C CZ . TYR B 2 37 ? -58.052 14.861 -0.341 1.00 64.01 ? 59 TYR B CZ 1 ATOM 5833 O OH . TYR B 2 37 ? -57.665 16.107 0.092 1.00 62.27 ? 59 TYR B OH 1 ATOM 5834 N N . ALA B 2 38 ? -61.341 8.423 -1.203 1.00 60.74 ? 60 ALA B N 1 ATOM 5835 C CA . ALA B 2 38 ? -61.897 7.208 -1.789 1.00 58.79 ? 60 ALA B CA 1 ATOM 5836 C C . ALA B 2 38 ? -62.951 7.543 -2.840 1.00 60.57 ? 60 ALA B C 1 ATOM 5837 O O . ALA B 2 38 ? -63.548 8.620 -2.807 1.00 60.16 ? 60 ALA B O 1 ATOM 5838 C CB . ALA B 2 38 ? -62.489 6.318 -0.708 1.00 62.99 ? 60 ALA B CB 1 ATOM 5839 N N . ALA B 2 39 ? -63.180 6.617 -3.767 1.00 60.33 ? 61 ALA B N 1 ATOM 5840 C CA . ALA B 2 39 ? -64.152 6.819 -4.839 1.00 57.12 ? 61 ALA B CA 1 ATOM 5841 C C . ALA B 2 39 ? -65.205 5.711 -4.837 1.00 58.99 ? 61 ALA B C 1 ATOM 5842 O O . ALA B 2 39 ? -64.881 4.550 -4.585 1.00 58.24 ? 61 ALA B O 1 ATOM 5843 C CB . ALA B 2 39 ? -63.443 6.875 -6.185 1.00 57.99 ? 61 ALA B CB 1 ATOM 5844 N N . PRO B 2 40 ? -66.468 6.069 -5.132 1.00 55.55 ? 62 PRO B N 1 ATOM 5845 C CA . PRO B 2 40 ? -67.614 5.148 -5.095 1.00 55.86 ? 62 PRO B CA 1 ATOM 5846 C C . PRO B 2 40 ? -67.448 3.923 -5.990 1.00 60.41 ? 62 PRO B C 1 ATOM 5847 O O . PRO B 2 40 ? -66.843 4.027 -7.055 1.00 70.86 ? 62 PRO B O 1 ATOM 5848 C CB . PRO B 2 40 ? -68.774 6.012 -5.606 1.00 53.73 ? 62 PRO B CB 1 ATOM 5849 C CG . PRO B 2 40 ? -68.127 7.169 -6.302 1.00 50.46 ? 62 PRO B CG 1 ATOM 5850 C CD . PRO B 2 40 ? -66.878 7.425 -5.533 1.00 50.83 ? 62 PRO B CD 1 ATOM 5851 N N . PRO B 2 41 ? -67.981 2.770 -5.554 1.00 63.09 ? 63 PRO B N 1 ATOM 5852 C CA . PRO B 2 41 ? -67.925 1.522 -6.323 1.00 69.15 ? 63 PRO B CA 1 ATOM 5853 C C . PRO B 2 41 ? -69.057 1.413 -7.345 1.00 77.31 ? 63 PRO B C 1 ATOM 5854 O O . PRO B 2 41 ? -69.960 0.590 -7.188 1.00 82.14 ? 63 PRO B O 1 ATOM 5855 C CB . PRO B 2 41 ? -68.077 0.447 -5.245 1.00 69.32 ? 63 PRO B CB 1 ATOM 5856 C CG . PRO B 2 41 ? -68.902 1.098 -4.192 1.00 72.08 ? 63 PRO B CG 1 ATOM 5857 C CD . PRO B 2 41 ? -68.546 2.564 -4.207 1.00 68.24 ? 63 PRO B CD 1 ATOM 5858 N N . VAL B 2 42 ? -68.994 2.243 -8.382 1.00 79.65 ? 64 VAL B N 1 ATOM 5859 C CA . VAL B 2 42 ? -69.993 2.239 -9.447 1.00 78.01 ? 64 VAL B CA 1 ATOM 5860 C C . VAL B 2 42 ? -69.334 2.510 -10.804 1.00 77.61 ? 64 VAL B C 1 ATOM 5861 O O . VAL B 2 42 ? -68.479 3.389 -10.918 1.00 75.81 ? 64 VAL B O 1 ATOM 5862 C CB . VAL B 2 42 ? -71.126 3.259 -9.152 1.00 76.25 ? 64 VAL B CB 1 ATOM 5863 C CG1 . VAL B 2 42 ? -70.550 4.580 -8.659 1.00 65.88 ? 64 VAL B CG1 1 ATOM 5864 C CG2 . VAL B 2 42 ? -72.019 3.461 -10.371 1.00 86.40 ? 64 VAL B CG2 1 ATOM 5865 N N . SER B 2 43 ? -69.724 1.741 -11.820 1.00 81.85 ? 65 SER B N 1 ATOM 5866 C CA . SER B 2 43 ? -69.127 1.845 -13.151 1.00 82.76 ? 65 SER B CA 1 ATOM 5867 C C . SER B 2 43 ? -69.283 3.241 -13.746 1.00 80.83 ? 65 SER B C 1 ATOM 5868 O O . SER B 2 43 ? -68.314 3.839 -14.213 1.00 85.55 ? 65 SER B O 1 ATOM 5869 C CB . SER B 2 43 ? -69.738 0.810 -14.100 1.00 77.29 ? 65 SER B CB 1 ATOM 5870 O OG . SER B 2 43 ? -71.075 1.147 -14.433 1.00 79.14 ? 65 SER B OG 1 ATOM 5871 N N . ASN B 2 44 ? -70.508 3.753 -13.726 1.00 71.62 ? 66 ASN B N 1 ATOM 5872 C CA . ASN B 2 44 ? -70.798 5.076 -14.262 1.00 74.87 ? 66 ASN B CA 1 ATOM 5873 C C . ASN B 2 44 ? -71.221 6.024 -13.145 1.00 72.06 ? 66 ASN B C 1 ATOM 5874 O O . ASN B 2 44 ? -72.293 5.860 -12.560 1.00 78.64 ? 66 ASN B O 1 ATOM 5875 C CB . ASN B 2 44 ? -71.893 4.981 -15.329 1.00 84.62 ? 66 ASN B CB 1 ATOM 5876 C CG . ASN B 2 44 ? -72.089 6.280 -16.092 1.00 82.11 ? 66 ASN B CG 1 ATOM 5877 O OD1 . ASN B 2 44 ? -71.136 6.872 -16.601 1.00 90.97 ? 66 ASN B OD1 1 ATOM 5878 N ND2 . ASN B 2 44 ? -73.331 6.739 -16.153 1.00 70.93 ? 66 ASN B ND2 1 ATOM 5879 N N . LEU B 2 45 ? -70.372 7.007 -12.852 1.00 69.19 ? 67 LEU B N 1 ATOM 5880 C CA . LEU B 2 45 ? -70.623 7.970 -11.781 1.00 72.56 ? 67 LEU B CA 1 ATOM 5881 C C . LEU B 2 45 ? -71.923 8.725 -12.005 1.00 76.06 ? 67 LEU B C 1 ATOM 5882 O O . LEU B 2 45 ? -72.745 8.847 -11.099 1.00 85.19 ? 67 LEU B O 1 ATOM 5883 C CB . LEU B 2 45 ? -69.483 8.990 -11.675 1.00 64.33 ? 67 LEU B CB 1 ATOM 5884 C CG . LEU B 2 45 ? -68.041 8.554 -11.425 1.00 54.56 ? 67 LEU B CG 1 ATOM 5885 C CD1 . LEU B 2 45 ? -67.416 8.051 -12.711 1.00 63.33 ? 67 LEU B CD1 1 ATOM 5886 C CD2 . LEU B 2 45 ? -67.232 9.710 -10.853 1.00 47.64 ? 67 LEU B CD2 1 ATOM 5887 N N . SER B 2 46 ? -72.087 9.232 -13.223 1.00 68.60 ? 68 SER B N 1 ATOM 5888 C CA . SER B 2 46 ? -73.244 10.031 -13.604 1.00 73.48 ? 68 SER B CA 1 ATOM 5889 C C . SER B 2 46 ? -74.569 9.368 -13.226 1.00 78.06 ? 68 SER B C 1 ATOM 5890 O O . SER B 2 46 ? -75.428 9.992 -12.606 1.00 73.11 ? 68 SER B O 1 ATOM 5891 C CB . SER B 2 46 ? -73.198 10.312 -15.107 1.00 82.10 ? 68 SER B CB 1 ATOM 5892 O OG . SER B 2 46 ? -71.971 10.922 -15.468 1.00 76.94 ? 68 SER B OG 1 ATOM 5893 N N . GLU B 2 47 ? -74.716 8.097 -13.588 1.00 78.93 ? 69 GLU B N 1 ATOM 5894 C CA . GLU B 2 47 ? -75.923 7.336 -13.281 1.00 78.30 ? 69 GLU B CA 1 ATOM 5895 C C . GLU B 2 47 ? -76.248 7.371 -11.791 1.00 79.03 ? 69 GLU B C 1 ATOM 5896 O O . GLU B 2 47 ? -77.382 7.645 -11.399 1.00 82.84 ? 69 GLU B O 1 ATOM 5897 C CB . GLU B 2 47 ? -75.768 5.885 -13.741 1.00 83.08 ? 69 GLU B CB 1 ATOM 5898 C CG . GLU B 2 47 ? -76.950 4.993 -13.392 1.00 89.94 ? 69 GLU B CG 1 ATOM 5899 C CD . GLU B 2 47 ? -76.703 3.534 -13.722 1.00 100.29 ? 69 GLU B CD 1 ATOM 5900 O OE1 . GLU B 2 47 ? -75.539 3.174 -13.997 1.00 104.03 ? 69 GLU B OE1 1 ATOM 5901 O OE2 . GLU B 2 47 ? -77.673 2.747 -13.706 1.00 104.54 ? 69 GLU B OE2 1 ATOM 5902 N N . ALA B 2 48 ? -75.245 7.098 -10.966 1.00 75.47 ? 70 ALA B N 1 ATOM 5903 C CA . ALA B 2 48 ? -75.432 7.065 -9.519 1.00 73.41 ? 70 ALA B CA 1 ATOM 5904 C C . ALA B 2 48 ? -75.430 8.445 -8.856 1.00 75.17 ? 70 ALA B C 1 ATOM 5905 O O . ALA B 2 48 ? -76.131 8.657 -7.867 1.00 81.73 ? 70 ALA B O 1 ATOM 5906 C CB . ALA B 2 48 ? -74.389 6.161 -8.872 1.00 71.62 ? 70 ALA B CB 1 ATOM 5907 N N . LEU B 2 49 ? -74.647 9.376 -9.399 1.00 75.76 ? 71 LEU B N 1 ATOM 5908 C CA . LEU B 2 49 ? -74.394 10.662 -8.736 1.00 74.90 ? 71 LEU B CA 1 ATOM 5909 C C . LEU B 2 49 ? -75.642 11.499 -8.459 1.00 77.06 ? 71 LEU B C 1 ATOM 5910 O O . LEU B 2 49 ? -76.576 11.536 -9.262 1.00 76.34 ? 71 LEU B O 1 ATOM 5911 C CB . LEU B 2 49 ? -73.374 11.497 -9.520 1.00 70.88 ? 71 LEU B CB 1 ATOM 5912 C CG . LEU B 2 49 ? -72.744 12.670 -8.760 1.00 56.13 ? 71 LEU B CG 1 ATOM 5913 C CD1 . LEU B 2 49 ? -71.863 12.154 -7.635 1.00 57.02 ? 71 LEU B CD1 1 ATOM 5914 C CD2 . LEU B 2 49 ? -71.956 13.585 -9.687 1.00 46.83 ? 71 LEU B CD2 1 ATOM 5915 N N . SER B 2 50 ? -75.636 12.166 -7.308 1.00 77.64 ? 72 SER B N 1 ATOM 5916 C CA . SER B 2 50 ? -76.703 13.077 -6.908 1.00 76.56 ? 72 SER B CA 1 ATOM 5917 C C . SER B 2 50 ? -76.210 14.524 -6.858 1.00 71.26 ? 72 SER B C 1 ATOM 5918 O O . SER B 2 50 ? -76.723 15.382 -7.574 1.00 66.20 ? 72 SER B O 1 ATOM 5919 C CB . SER B 2 50 ? -77.309 12.661 -5.564 1.00 83.05 ? 72 SER B CB 1 ATOM 5920 O OG . SER B 2 50 ? -78.124 11.510 -5.707 1.00 82.37 ? 72 SER B OG 1 ATOM 5921 N N . GLY B 2 51 ? -75.231 14.803 -6.001 1.00 70.94 ? 73 GLY B N 1 ATOM 5922 C CA . GLY B 2 51 ? -74.709 16.156 -5.897 1.00 71.47 ? 73 GLY B CA 1 ATOM 5923 C C . GLY B 2 51 ? -73.256 16.317 -5.488 1.00 74.95 ? 73 GLY B C 1 ATOM 5924 O O . GLY B 2 51 ? -72.650 15.422 -4.898 1.00 71.21 ? 73 GLY B O 1 ATOM 5925 N N . ILE B 2 52 ? -72.704 17.485 -5.811 1.00 71.83 ? 74 ILE B N 1 ATOM 5926 C CA . ILE B 2 52 ? -71.320 17.820 -5.499 1.00 61.94 ? 74 ILE B CA 1 ATOM 5927 C C . ILE B 2 52 ? -71.271 18.984 -4.510 1.00 62.15 ? 74 ILE B C 1 ATOM 5928 O O . ILE B 2 52 ? -71.650 20.105 -4.845 1.00 63.57 ? 74 ILE B O 1 ATOM 5929 C CB . ILE B 2 52 ? -70.547 18.214 -6.781 1.00 55.88 ? 74 ILE B CB 1 ATOM 5930 C CG1 . ILE B 2 52 ? -70.574 17.071 -7.799 1.00 48.07 ? 74 ILE B CG1 1 ATOM 5931 C CG2 . ILE B 2 52 ? -69.115 18.602 -6.456 1.00 59.13 ? 74 ILE B CG2 1 ATOM 5932 C CD1 . ILE B 2 52 ? -69.834 17.377 -9.084 1.00 38.70 ? 74 ILE B CD1 1 ATOM 5933 N N . VAL B 2 53 ? -70.806 18.718 -3.293 1.00 59.60 ? 75 VAL B N 1 ATOM 5934 C CA . VAL B 2 53 ? -70.668 19.766 -2.287 1.00 60.74 ? 75 VAL B CA 1 ATOM 5935 C C . VAL B 2 53 ? -69.197 20.114 -2.078 1.00 66.52 ? 75 VAL B C 1 ATOM 5936 O O . VAL B 2 53 ? -68.400 19.260 -1.692 1.00 68.21 ? 75 VAL B O 1 ATOM 5937 C CB . VAL B 2 53 ? -71.301 19.354 -0.941 1.00 68.16 ? 75 VAL B CB 1 ATOM 5938 C CG1 . VAL B 2 53 ? -71.031 20.407 0.121 1.00 71.89 ? 75 VAL B CG1 1 ATOM 5939 C CG2 . VAL B 2 53 ? -72.795 19.130 -1.102 1.00 69.04 ? 75 VAL B CG2 1 ATOM 5940 N N . VAL B 2 54 ? -68.844 21.369 -2.344 1.00 72.33 ? 76 VAL B N 1 ATOM 5941 C CA . VAL B 2 54 ? -67.463 21.828 -2.213 1.00 75.38 ? 76 VAL B CA 1 ATOM 5942 C C . VAL B 2 54 ? -67.333 22.872 -1.107 1.00 81.03 ? 76 VAL B C 1 ATOM 5943 O O . VAL B 2 54 ? -67.995 23.909 -1.143 1.00 83.98 ? 76 VAL B O 1 ATOM 5944 C CB . VAL B 2 54 ? -66.944 22.428 -3.535 1.00 68.14 ? 76 VAL B CB 1 ATOM 5945 C CG1 . VAL B 2 54 ? -65.510 22.903 -3.382 1.00 66.25 ? 76 VAL B CG1 1 ATOM 5946 C CG2 . VAL B 2 54 ? -67.049 21.408 -4.650 1.00 66.74 ? 76 VAL B CG2 1 ATOM 5947 N N . LYS B 2 55 ? -66.480 22.591 -0.126 1.00 78.09 ? 77 LYS B N 1 ATOM 5948 C CA . LYS B 2 55 ? -66.239 23.516 0.978 1.00 75.98 ? 77 LYS B CA 1 ATOM 5949 C C . LYS B 2 55 ? -64.933 24.282 0.773 1.00 74.73 ? 77 LYS B C 1 ATOM 5950 O O . LYS B 2 55 ? -63.856 23.691 0.713 1.00 74.05 ? 77 LYS B O 1 ATOM 5951 C CB . LYS B 2 55 ? -66.234 22.769 2.316 1.00 76.09 ? 77 LYS B CB 1 ATOM 5952 C CG . LYS B 2 55 ? -67.615 22.295 2.763 1.00 76.80 ? 77 LYS B CG 1 ATOM 5953 C CD . LYS B 2 55 ? -67.532 21.301 3.914 1.00 86.14 ? 77 LYS B CD 1 ATOM 5954 C CE . LYS B 2 55 ? -68.902 21.045 4.528 1.00 79.44 ? 77 LYS B CE 1 ATOM 5955 N NZ . LYS B 2 55 ? -69.443 22.256 5.209 1.00 73.96 ? 77 LYS B NZ 1 ATOM 5956 N N . THR B 2 56 ? -65.048 25.603 0.667 1.00 77.27 ? 78 THR B N 1 ATOM 5957 C CA . THR B 2 56 ? -63.923 26.476 0.332 1.00 73.60 ? 78 THR B CA 1 ATOM 5958 C C . THR B 2 56 ? -62.973 26.750 1.502 1.00 82.04 ? 78 THR B C 1 ATOM 5959 O O . THR B 2 56 ? -61.803 26.371 1.462 1.00 88.36 ? 78 THR B O 1 ATOM 5960 C CB . THR B 2 56 ? -64.421 27.822 -0.250 1.00 70.14 ? 78 THR B CB 1 ATOM 5961 O OG1 . THR B 2 56 ? -65.044 27.595 -1.521 1.00 66.25 ? 78 THR B OG1 1 ATOM 5962 C CG2 . THR B 2 56 ? -63.272 28.797 -0.430 1.00 68.74 ? 78 THR B CG2 1 ATOM 5963 N N . LYS B 2 57 ? -63.482 27.410 2.539 1.00 85.09 ? 79 LYS B N 1 ATOM 5964 C CA . LYS B 2 57 ? -62.642 27.953 3.609 1.00 89.28 ? 79 LYS B CA 1 ATOM 5965 C C . LYS B 2 57 ? -61.897 26.949 4.498 1.00 85.12 ? 79 LYS B C 1 ATOM 5966 O O . LYS B 2 57 ? -61.075 27.353 5.321 1.00 90.57 ? 79 LYS B O 1 ATOM 5967 C CB . LYS B 2 57 ? -63.450 28.919 4.481 1.00 98.33 ? 79 LYS B CB 1 ATOM 5968 C CG . LYS B 2 57 ? -63.488 30.341 3.955 1.00 99.35 ? 79 LYS B CG 1 ATOM 5969 C CD . LYS B 2 57 ? -62.084 30.839 3.649 1.00 93.38 ? 79 LYS B CD 1 ATOM 5970 C CE . LYS B 2 57 ? -62.038 32.354 3.581 1.00 103.29 ? 79 LYS B CE 1 ATOM 5971 N NZ . LYS B 2 57 ? -63.162 32.905 2.778 1.00 108.19 ? 79 LYS B NZ 1 ATOM 5972 N N . CYS B 2 58 ? -62.188 25.660 4.349 1.00 77.03 ? 80 CYS B N 1 ATOM 5973 C CA . CYS B 2 58 ? -61.499 24.624 5.121 1.00 79.12 ? 80 CYS B CA 1 ATOM 5974 C C . CYS B 2 58 ? -59.987 24.681 4.888 1.00 88.20 ? 80 CYS B C 1 ATOM 5975 O O . CYS B 2 58 ? -59.550 25.116 3.822 1.00 93.92 ? 80 CYS B O 1 ATOM 5976 C CB . CYS B 2 58 ? -62.045 23.241 4.752 1.00 83.21 ? 80 CYS B CB 1 ATOM 5977 S SG . CYS B 2 58 ? -63.754 22.959 5.261 1.00 108.90 ? 80 CYS B SG 1 ATOM 5978 N N . PRO B 2 59 ? -59.185 24.255 5.887 1.00 92.29 ? 81 PRO B N 1 ATOM 5979 C CA . PRO B 2 59 ? -57.716 24.300 5.799 1.00 84.73 ? 81 PRO B CA 1 ATOM 5980 C C . PRO B 2 59 ? -57.205 23.652 4.520 1.00 84.18 ? 81 PRO B C 1 ATOM 5981 O O . PRO B 2 59 ? -56.332 24.198 3.845 1.00 86.01 ? 81 PRO B O 1 ATOM 5982 C CB . PRO B 2 59 ? -57.272 23.474 7.008 1.00 83.24 ? 81 PRO B CB 1 ATOM 5983 C CG . PRO B 2 59 ? -58.367 23.635 7.989 1.00 97.94 ? 81 PRO B CG 1 ATOM 5984 C CD . PRO B 2 59 ? -59.636 23.710 7.182 1.00 99.14 ? 81 PRO B CD 1 ATOM 5985 N N . VAL B 2 60 ? -57.766 22.496 4.195 1.00 82.91 ? 82 VAL B N 1 ATOM 5986 C CA . VAL B 2 60 ? -57.529 21.842 2.921 1.00 78.00 ? 82 VAL B CA 1 ATOM 5987 C C . VAL B 2 60 ? -58.898 21.679 2.291 1.00 80.60 ? 82 VAL B C 1 ATOM 5988 O O . VAL B 2 60 ? -59.588 20.699 2.573 1.00 85.86 ? 82 VAL B O 1 ATOM 5989 C CB . VAL B 2 60 ? -56.893 20.457 3.105 1.00 84.08 ? 82 VAL B CB 1 ATOM 5990 C CG1 . VAL B 2 60 ? -56.591 19.829 1.751 1.00 81.40 ? 82 VAL B CG1 1 ATOM 5991 C CG2 . VAL B 2 60 ? -55.630 20.567 3.942 1.00 96.67 ? 82 VAL B CG2 1 ATOM 5992 N N . PRO B 2 61 ? -59.303 22.653 1.453 1.00 80.84 ? 83 PRO B N 1 ATOM 5993 C CA . PRO B 2 61 ? -60.687 22.754 0.974 1.00 78.31 ? 83 PRO B CA 1 ATOM 5994 C C . PRO B 2 61 ? -61.152 21.434 0.393 1.00 70.62 ? 83 PRO B C 1 ATOM 5995 O O . PRO B 2 61 ? -60.463 20.874 -0.448 1.00 65.78 ? 83 PRO B O 1 ATOM 5996 C CB . PRO B 2 61 ? -60.604 23.817 -0.129 1.00 69.09 ? 83 PRO B CB 1 ATOM 5997 C CG . PRO B 2 61 ? -59.156 23.908 -0.490 1.00 73.83 ? 83 PRO B CG 1 ATOM 5998 C CD . PRO B 2 61 ? -58.416 23.615 0.777 1.00 75.50 ? 83 PRO B CD 1 ATOM 5999 N N . GLU B 2 62 ? -62.303 20.948 0.841 1.00 73.04 ? 84 GLU B N 1 ATOM 6000 C CA . GLU B 2 62 ? -62.711 19.583 0.545 1.00 72.84 ? 84 GLU B CA 1 ATOM 6001 C C . GLU B 2 62 ? -63.879 19.516 -0.428 1.00 71.26 ? 84 GLU B C 1 ATOM 6002 O O . GLU B 2 62 ? -64.747 20.388 -0.438 1.00 71.15 ? 84 GLU B O 1 ATOM 6003 C CB . GLU B 2 62 ? -63.067 18.849 1.841 1.00 75.37 ? 84 GLU B CB 1 ATOM 6004 C CG . GLU B 2 62 ? -64.136 19.544 2.671 1.00 79.04 ? 84 GLU B CG 1 ATOM 6005 C CD . GLU B 2 62 ? -64.467 18.795 3.947 1.00 85.81 ? 84 GLU B CD 1 ATOM 6006 O OE1 . GLU B 2 62 ? -65.667 18.554 4.202 1.00 79.83 ? 84 GLU B OE1 1 ATOM 6007 O OE2 . GLU B 2 62 ? -63.530 18.452 4.697 1.00 93.68 ? 84 GLU B OE2 1 ATOM 6008 N N . VAL B 2 63 ? -63.890 18.473 -1.250 1.00 66.35 ? 85 VAL B N 1 ATOM 6009 C CA . VAL B 2 63 ? -64.991 18.240 -2.172 1.00 70.68 ? 85 VAL B CA 1 ATOM 6010 C C . VAL B 2 63 ? -65.668 16.921 -1.816 1.00 72.06 ? 85 VAL B C 1 ATOM 6011 O O . VAL B 2 63 ? -65.005 15.893 -1.667 1.00 65.27 ? 85 VAL B O 1 ATOM 6012 C CB . VAL B 2 63 ? -64.516 18.237 -3.639 1.00 72.62 ? 85 VAL B CB 1 ATOM 6013 C CG1 . VAL B 2 63 ? -65.658 17.878 -4.574 1.00 66.75 ? 85 VAL B CG1 1 ATOM 6014 C CG2 . VAL B 2 63 ? -63.942 19.594 -4.007 1.00 73.05 ? 85 VAL B CG2 1 ATOM 6015 N N . ILE B 2 64 ? -66.989 16.964 -1.664 1.00 73.79 ? 86 ILE B N 1 ATOM 6016 C CA . ILE B 2 64 ? -67.754 15.792 -1.255 1.00 68.01 ? 86 ILE B CA 1 ATOM 6017 C C . ILE B 2 64 ? -68.751 15.370 -2.335 1.00 63.72 ? 86 ILE B C 1 ATOM 6018 O O . ILE B 2 64 ? -69.607 16.153 -2.746 1.00 57.73 ? 86 ILE B O 1 ATOM 6019 C CB . ILE B 2 64 ? -68.509 16.048 0.071 1.00 68.28 ? 86 ILE B CB 1 ATOM 6020 C CG1 . ILE B 2 64 ? -67.609 16.780 1.070 1.00 68.34 ? 86 ILE B CG1 1 ATOM 6021 C CG2 . ILE B 2 64 ? -69.008 14.740 0.663 1.00 71.93 ? 86 ILE B CG2 1 ATOM 6022 C CD1 . ILE B 2 64 ? -68.304 17.181 2.356 1.00 63.26 ? 86 ILE B CD1 1 ATOM 6023 N N . LEU B 2 65 ? -68.626 14.129 -2.796 1.00 65.06 ? 87 LEU B N 1 ATOM 6024 C CA . LEU B 2 65 ? -69.574 13.567 -3.750 1.00 66.56 ? 87 LEU B CA 1 ATOM 6025 C C . LEU B 2 65 ? -70.614 12.759 -2.992 1.00 68.42 ? 87 LEU B C 1 ATOM 6026 O O . LEU B 2 65 ? -70.271 11.867 -2.215 1.00 63.92 ? 87 LEU B O 1 ATOM 6027 C CB . LEU B 2 65 ? -68.859 12.679 -4.770 1.00 67.74 ? 87 LEU B CB 1 ATOM 6028 C CG . LEU B 2 65 ? -67.798 13.365 -5.632 1.00 61.15 ? 87 LEU B CG 1 ATOM 6029 C CD1 . LEU B 2 65 ? -67.163 12.390 -6.620 1.00 51.35 ? 87 LEU B CD1 1 ATOM 6030 C CD2 . LEU B 2 65 ? -68.403 14.553 -6.357 1.00 56.54 ? 87 LEU B CD2 1 ATOM 6031 N N . TRP B 2 66 ? -71.886 13.074 -3.215 1.00 74.12 ? 88 TRP B N 1 ATOM 6032 C CA . TRP B 2 66 ? -72.962 12.438 -2.464 1.00 83.24 ? 88 TRP B CA 1 ATOM 6033 C C . TRP B 2 66 ? -73.971 11.712 -3.352 1.00 78.21 ? 88 TRP B C 1 ATOM 6034 O O . TRP B 2 66 ? -74.337 12.189 -4.428 1.00 66.78 ? 88 TRP B O 1 ATOM 6035 C CB . TRP B 2 66 ? -73.670 13.461 -1.568 1.00 90.10 ? 88 TRP B CB 1 ATOM 6036 C CG . TRP B 2 66 ? -74.864 12.904 -0.856 1.00 89.30 ? 88 TRP B CG 1 ATOM 6037 C CD1 . TRP B 2 66 ? -74.861 12.058 0.215 1.00 84.96 ? 88 TRP B CD1 1 ATOM 6038 C CD2 . TRP B 2 66 ? -76.238 13.158 -1.164 1.00 87.36 ? 88 TRP B CD2 1 ATOM 6039 N NE1 . TRP B 2 66 ? -76.149 11.767 0.590 1.00 86.61 ? 88 TRP B NE1 1 ATOM 6040 C CE2 . TRP B 2 66 ? -77.014 12.430 -0.241 1.00 86.28 ? 88 TRP B CE2 1 ATOM 6041 C CE3 . TRP B 2 66 ? -76.888 13.929 -2.131 1.00 85.66 ? 88 TRP B CE3 1 ATOM 6042 C CZ2 . TRP B 2 66 ? -78.407 12.451 -0.258 1.00 95.55 ? 88 TRP B CZ2 1 ATOM 6043 C CZ3 . TRP B 2 66 ? -78.269 13.948 -2.146 1.00 88.45 ? 88 TRP B CZ3 1 ATOM 6044 C CH2 . TRP B 2 66 ? -79.012 13.215 -1.217 1.00 94.07 ? 88 TRP B CH2 1 ATOM 6045 N N . PHE B 2 67 ? -74.415 10.552 -2.881 1.00 81.35 ? 89 PHE B N 1 ATOM 6046 C CA . PHE B 2 67 ? -75.391 9.742 -3.595 1.00 78.80 ? 89 PHE B CA 1 ATOM 6047 C C . PHE B 2 67 ? -76.623 9.538 -2.717 1.00 92.90 ? 89 PHE B C 1 ATOM 6048 O O . PHE B 2 67 ? -76.519 9.488 -1.492 1.00 94.14 ? 89 PHE B O 1 ATOM 6049 C CB . PHE B 2 67 ? -74.780 8.393 -3.980 1.00 72.96 ? 89 PHE B CB 1 ATOM 6050 C CG . PHE B 2 67 ? -73.493 8.507 -4.750 1.00 76.57 ? 89 PHE B CG 1 ATOM 6051 C CD1 . PHE B 2 67 ? -72.282 8.646 -4.091 1.00 79.79 ? 89 PHE B CD1 1 ATOM 6052 C CD2 . PHE B 2 67 ? -73.495 8.472 -6.132 1.00 78.14 ? 89 PHE B CD2 1 ATOM 6053 C CE1 . PHE B 2 67 ? -71.100 8.753 -4.799 1.00 77.63 ? 89 PHE B CE1 1 ATOM 6054 C CE2 . PHE B 2 67 ? -72.316 8.576 -6.846 1.00 76.39 ? 89 PHE B CE2 1 ATOM 6055 C CZ . PHE B 2 67 ? -71.120 8.719 -6.179 1.00 74.57 ? 89 PHE B CZ 1 ATOM 6056 N N . LYS B 2 68 ? -77.789 9.425 -3.345 1.00 96.37 ? 90 LYS B N 1 ATOM 6057 C CA . LYS B 2 68 ? -79.045 9.300 -2.609 1.00 91.57 ? 90 LYS B CA 1 ATOM 6058 C C . LYS B 2 68 ? -79.414 7.853 -2.300 1.00 93.73 ? 90 LYS B C 1 ATOM 6059 O O . LYS B 2 68 ? -79.483 7.457 -1.140 1.00 96.72 ? 90 LYS B O 1 ATOM 6060 C CB . LYS B 2 68 ? -80.189 9.966 -3.376 1.00 97.19 ? 90 LYS B CB 1 ATOM 6061 C CG . LYS B 2 68 ? -81.552 9.796 -2.720 1.00 98.52 ? 90 LYS B CG 1 ATOM 6062 C CD . LYS B 2 68 ? -82.666 10.289 -3.630 1.00 107.05 ? 90 LYS B CD 1 ATOM 6063 C CE . LYS B 2 68 ? -83.996 10.361 -2.898 1.00 104.21 ? 90 LYS B CE 1 ATOM 6064 N NZ . LYS B 2 68 ? -85.041 11.039 -3.713 1.00 91.93 ? 90 LYS B NZ 1 ATOM 6065 N N . ASP B 2 69 ? -79.667 7.075 -3.347 1.00 95.30 ? 91 ASP B N 1 ATOM 6066 C CA . ASP B 2 69 ? -80.148 5.706 -3.196 1.00 90.51 ? 91 ASP B CA 1 ATOM 6067 C C . ASP B 2 69 ? -79.129 4.797 -2.509 1.00 93.14 ? 91 ASP B C 1 ATOM 6068 O O . ASP B 2 69 ? -79.497 3.807 -1.877 1.00 100.90 ? 91 ASP B O 1 ATOM 6069 C CB . ASP B 2 69 ? -80.563 5.137 -4.553 1.00 95.18 ? 91 ASP B CB 1 ATOM 6070 C CG . ASP B 2 69 ? -81.578 6.015 -5.261 1.00 108.56 ? 91 ASP B CG 1 ATOM 6071 O OD1 . ASP B 2 69 ? -82.365 6.695 -4.567 1.00 104.03 ? 91 ASP B OD1 1 ATOM 6072 O OD2 . ASP B 2 69 ? -81.589 6.031 -6.511 1.00 116.30 ? 91 ASP B OD2 1 ATOM 6073 N N . LYS B 2 70 ? -77.850 5.127 -2.648 1.00 96.29 ? 92 LYS B N 1 ATOM 6074 C CA . LYS B 2 70 ? -76.804 4.454 -1.887 1.00 99.53 ? 92 LYS B CA 1 ATOM 6075 C C . LYS B 2 70 ? -76.747 5.062 -0.489 1.00 88.28 ? 92 LYS B C 1 ATOM 6076 O O . LYS B 2 70 ? -76.397 4.389 0.482 1.00 83.83 ? 92 LYS B O 1 ATOM 6077 C CB . LYS B 2 70 ? -75.442 4.619 -2.569 1.00 104.41 ? 92 LYS B CB 1 ATOM 6078 C CG . LYS B 2 70 ? -75.445 4.406 -4.080 1.00 97.93 ? 92 LYS B CG 1 ATOM 6079 C CD . LYS B 2 70 ? -75.541 2.934 -4.456 1.00 106.07 ? 92 LYS B CD 1 ATOM 6080 C CE . LYS B 2 70 ? -75.473 2.751 -5.969 1.00 102.92 ? 92 LYS B CE 1 ATOM 6081 N NZ . LYS B 2 70 ? -75.506 1.317 -6.376 1.00 100.85 ? 92 LYS B NZ 1 ATOM 6082 N N . GLN B 2 71 ? -77.110 6.341 -0.407 1.00 85.43 ? 93 GLN B N 1 ATOM 6083 C CA . GLN B 2 71 ? -76.999 7.134 0.820 1.00 85.92 ? 93 GLN B CA 1 ATOM 6084 C C . GLN B 2 71 ? -75.583 7.152 1.396 1.00 88.85 ? 93 GLN B C 1 ATOM 6085 O O . GLN B 2 71 ? -75.368 6.835 2.566 1.00 93.44 ? 93 GLN B O 1 ATOM 6086 C CB . GLN B 2 71 ? -78.026 6.699 1.870 1.00 89.36 ? 93 GLN B CB 1 ATOM 6087 C CG . GLN B 2 71 ? -79.209 7.649 1.990 1.00 88.92 ? 93 GLN B CG 1 ATOM 6088 C CD . GLN B 2 71 ? -80.178 7.248 3.082 1.00 96.75 ? 93 GLN B CD 1 ATOM 6089 O OE1 . GLN B 2 71 ? -81.324 7.698 3.106 1.00 102.53 ? 93 GLN B OE1 1 ATOM 6090 N NE2 . GLN B 2 71 ? -79.722 6.402 3.997 1.00 94.76 ? 93 GLN B NE2 1 ATOM 6091 N N . MET B 2 72 ? -74.624 7.531 0.557 1.00 78.64 ? 94 MET B N 1 ATOM 6092 C CA . MET B 2 72 ? -73.231 7.635 0.968 1.00 79.57 ? 94 MET B CA 1 ATOM 6093 C C . MET B 2 72 ? -72.640 8.968 0.521 1.00 79.26 ? 94 MET B C 1 ATOM 6094 O O . MET B 2 72 ? -73.130 9.587 -0.422 1.00 75.83 ? 94 MET B O 1 ATOM 6095 C CB . MET B 2 72 ? -72.414 6.486 0.374 1.00 82.03 ? 94 MET B CB 1 ATOM 6096 C CG . MET B 2 72 ? -72.775 5.111 0.905 1.00 85.83 ? 94 MET B CG 1 ATOM 6097 S SD . MET B 2 72 ? -72.419 4.916 2.662 1.00 100.75 ? 94 MET B SD 1 ATOM 6098 C CE . MET B 2 72 ? -70.680 5.351 2.712 1.00 78.60 ? 94 MET B CE 1 ATOM 6099 N N . ALA B 2 73 ? -71.585 9.403 1.203 1.00 80.07 ? 95 ALA B N 1 ATOM 6100 C CA . ALA B 2 73 ? -70.867 10.616 0.825 1.00 77.57 ? 95 ALA B CA 1 ATOM 6101 C C . ALA B 2 73 ? -69.365 10.354 0.797 1.00 81.16 ? 95 ALA B C 1 ATOM 6102 O O . ALA B 2 73 ? -68.778 9.974 1.811 1.00 80.39 ? 95 ALA B O 1 ATOM 6103 C CB . ALA B 2 73 ? -71.192 11.749 1.782 1.00 75.34 ? 95 ALA B CB 1 ATOM 6104 N N . TYR B 2 74 ? -68.745 10.565 -0.361 1.00 77.94 ? 96 TYR B N 1 ATOM 6105 C CA . TYR B 2 74 ? -67.323 10.275 -0.531 1.00 69.03 ? 96 TYR B CA 1 ATOM 6106 C C . TYR B 2 74 ? -66.482 11.539 -0.691 1.00 62.41 ? 96 TYR B C 1 ATOM 6107 O O . TYR B 2 74 ? -66.916 12.518 -1.299 1.00 55.50 ? 96 TYR B O 1 ATOM 6108 C CB . TYR B 2 74 ? -67.102 9.355 -1.735 1.00 63.60 ? 96 TYR B CB 1 ATOM 6109 C CG . TYR B 2 74 ? -67.817 8.025 -1.644 1.00 63.83 ? 96 TYR B CG 1 ATOM 6110 C CD1 . TYR B 2 74 ? -67.179 6.903 -1.133 1.00 60.56 ? 96 TYR B CD1 1 ATOM 6111 C CD2 . TYR B 2 74 ? -69.128 7.890 -2.079 1.00 61.89 ? 96 TYR B CD2 1 ATOM 6112 C CE1 . TYR B 2 74 ? -67.828 5.686 -1.053 1.00 57.24 ? 96 TYR B CE1 1 ATOM 6113 C CE2 . TYR B 2 74 ? -69.785 6.677 -2.003 1.00 63.05 ? 96 TYR B CE2 1 ATOM 6114 C CZ . TYR B 2 74 ? -69.130 5.579 -1.489 1.00 60.22 ? 96 TYR B CZ 1 ATOM 6115 O OH . TYR B 2 74 ? -69.782 4.370 -1.411 1.00 61.69 ? 96 TYR B OH 1 ATOM 6116 N N . TRP B 2 75 ? -65.273 11.505 -0.139 1.00 66.46 ? 97 TRP B N 1 ATOM 6117 C CA . TRP B 2 75 ? -64.328 12.608 -0.278 1.00 68.38 ? 97 TRP B CA 1 ATOM 6118 C C . TRP B 2 75 ? -63.306 12.299 -1.370 1.00 69.24 ? 97 TRP B C 1 ATOM 6119 O O . TRP B 2 75 ? -62.630 11.272 -1.328 1.00 68.23 ? 97 TRP B O 1 ATOM 6120 C CB . TRP B 2 75 ? -63.620 12.884 1.053 1.00 69.62 ? 97 TRP B CB 1 ATOM 6121 C CG . TRP B 2 75 ? -64.389 13.790 1.972 1.00 74.17 ? 97 TRP B CG 1 ATOM 6122 C CD1 . TRP B 2 75 ? -64.184 15.126 2.166 1.00 78.09 ? 97 TRP B CD1 1 ATOM 6123 C CD2 . TRP B 2 75 ? -65.488 13.428 2.818 1.00 74.33 ? 97 TRP B CD2 1 ATOM 6124 N NE1 . TRP B 2 75 ? -65.086 15.617 3.080 1.00 76.72 ? 97 TRP B NE1 1 ATOM 6125 C CE2 . TRP B 2 75 ? -65.898 14.594 3.495 1.00 72.36 ? 97 TRP B CE2 1 ATOM 6126 C CE3 . TRP B 2 75 ? -66.164 12.231 3.068 1.00 76.33 ? 97 TRP B CE3 1 ATOM 6127 C CZ2 . TRP B 2 75 ? -66.953 14.597 4.405 1.00 73.88 ? 97 TRP B CZ2 1 ATOM 6128 C CZ3 . TRP B 2 75 ? -67.210 12.236 3.970 1.00 81.59 ? 97 TRP B CZ3 1 ATOM 6129 C CH2 . TRP B 2 75 ? -67.595 13.410 4.627 1.00 82.01 ? 97 TRP B CH2 1 ATOM 6130 N N . THR B 2 76 ? -63.197 13.199 -2.343 1.00 68.98 ? 98 THR B N 1 ATOM 6131 C CA . THR B 2 76 ? -62.307 13.015 -3.486 1.00 64.51 ? 98 THR B CA 1 ATOM 6132 C C . THR B 2 76 ? -61.378 14.219 -3.627 1.00 64.04 ? 98 THR B C 1 ATOM 6133 O O . THR B 2 76 ? -61.596 15.246 -2.982 1.00 66.09 ? 98 THR B O 1 ATOM 6134 C CB . THR B 2 76 ? -63.097 12.801 -4.794 1.00 57.45 ? 98 THR B CB 1 ATOM 6135 O OG1 . THR B 2 76 ? -63.839 13.985 -5.109 1.00 58.14 ? 98 THR B OG1 1 ATOM 6136 C CG2 . THR B 2 76 ? -64.060 11.629 -4.653 1.00 54.30 ? 98 THR B CG2 1 ATOM 6137 N N . ASN B 2 77 ? -60.342 14.083 -4.453 1.00 57.39 ? 99 ASN B N 1 ATOM 6138 C CA . ASN B 2 77 ? -59.343 15.137 -4.632 1.00 54.14 ? 99 ASN B CA 1 ATOM 6139 C C . ASN B 2 77 ? -59.990 16.463 -5.005 1.00 54.73 ? 99 ASN B C 1 ATOM 6140 O O . ASN B 2 77 ? -60.659 16.567 -6.030 1.00 58.87 ? 99 ASN B O 1 ATOM 6141 C CB . ASN B 2 77 ? -58.332 14.725 -5.705 1.00 55.79 ? 99 ASN B CB 1 ATOM 6142 C CG . ASN B 2 77 ? -57.128 15.650 -5.776 1.00 58.26 ? 99 ASN B CG 1 ATOM 6143 O OD1 . ASN B 2 77 ? -57.257 16.874 -5.774 1.00 56.90 ? 99 ASN B OD1 1 ATOM 6144 N ND2 . ASN B 2 77 ? -55.941 15.058 -5.855 1.00 58.72 ? 99 ASN B ND2 1 ATOM 6145 N N . PRO B 2 78 ? -59.782 17.484 -4.164 1.00 55.27 ? 100 PRO B N 1 ATOM 6146 C CA . PRO B 2 78 ? -60.452 18.785 -4.255 1.00 54.61 ? 100 PRO B CA 1 ATOM 6147 C C . PRO B 2 78 ? -60.180 19.528 -5.553 1.00 56.91 ? 100 PRO B C 1 ATOM 6148 O O . PRO B 2 78 ? -61.112 20.034 -6.175 1.00 59.64 ? 100 PRO B O 1 ATOM 6149 C CB . PRO B 2 78 ? -59.840 19.567 -3.093 1.00 59.51 ? 100 PRO B CB 1 ATOM 6150 C CG . PRO B 2 78 ? -59.355 18.528 -2.144 1.00 67.58 ? 100 PRO B CG 1 ATOM 6151 C CD . PRO B 2 78 ? -58.879 17.409 -3.003 1.00 61.97 ? 100 PRO B CD 1 ATOM 6152 N N . TYR B 2 79 ? -58.913 19.589 -5.948 1.00 55.67 ? 101 TYR B N 1 ATOM 6153 C CA . TYR B 2 79 ? -58.499 20.361 -7.112 1.00 56.35 ? 101 TYR B CA 1 ATOM 6154 C C . TYR B 2 79 ? -58.781 19.627 -8.420 1.00 52.23 ? 101 TYR B C 1 ATOM 6155 O O . TYR B 2 79 ? -59.214 20.231 -9.401 1.00 46.33 ? 101 TYR B O 1 ATOM 6156 C CB . TYR B 2 79 ? -57.011 20.697 -7.004 1.00 57.41 ? 101 TYR B CB 1 ATOM 6157 C CG . TYR B 2 79 ? -56.643 21.424 -5.729 1.00 60.65 ? 101 TYR B CG 1 ATOM 6158 C CD1 . TYR B 2 79 ? -57.369 22.526 -5.298 1.00 59.35 ? 101 TYR B CD1 1 ATOM 6159 C CD2 . TYR B 2 79 ? -55.575 21.000 -4.952 1.00 67.67 ? 101 TYR B CD2 1 ATOM 6160 C CE1 . TYR B 2 79 ? -57.033 23.191 -4.133 1.00 62.57 ? 101 TYR B CE1 1 ATOM 6161 C CE2 . TYR B 2 79 ? -55.234 21.657 -3.785 1.00 69.72 ? 101 TYR B CE2 1 ATOM 6162 C CZ . TYR B 2 79 ? -55.966 22.752 -3.381 1.00 67.47 ? 101 TYR B CZ 1 ATOM 6163 O OH . TYR B 2 79 ? -55.628 23.408 -2.220 1.00 67.18 ? 101 TYR B OH 1 ATOM 6164 N N . VAL B 2 80 ? -58.532 18.321 -8.423 1.00 50.91 ? 102 VAL B N 1 ATOM 6165 C CA . VAL B 2 80 ? -58.734 17.494 -9.611 1.00 49.83 ? 102 VAL B CA 1 ATOM 6166 C C . VAL B 2 80 ? -60.216 17.328 -9.966 1.00 50.70 ? 102 VAL B C 1 ATOM 6167 O O . VAL B 2 80 ? -60.601 17.502 -11.123 1.00 52.26 ? 102 VAL B O 1 ATOM 6168 C CB . VAL B 2 80 ? -58.067 16.110 -9.456 1.00 46.62 ? 102 VAL B CB 1 ATOM 6169 C CG1 . VAL B 2 80 ? -58.212 15.306 -10.732 1.00 46.87 ? 102 VAL B CG1 1 ATOM 6170 C CG2 . VAL B 2 80 ? -56.597 16.267 -9.106 1.00 41.61 ? 102 VAL B CG2 1 ATOM 6171 N N . THR B 2 81 ? -61.036 16.995 -8.970 1.00 50.18 ? 103 THR B N 1 ATOM 6172 C CA . THR B 2 81 ? -62.476 16.816 -9.167 1.00 50.22 ? 103 THR B CA 1 ATOM 6173 C C . THR B 2 81 ? -63.115 18.022 -9.843 1.00 51.56 ? 103 THR B C 1 ATOM 6174 O O . THR B 2 81 ? -63.847 17.881 -10.822 1.00 51.45 ? 103 THR B O 1 ATOM 6175 C CB . THR B 2 81 ? -63.200 16.574 -7.828 1.00 54.75 ? 103 THR B CB 1 ATOM 6176 O OG1 . THR B 2 81 ? -62.828 15.292 -7.305 1.00 59.33 ? 103 THR B OG1 1 ATOM 6177 C CG2 . THR B 2 81 ? -64.708 16.623 -8.012 1.00 52.84 ? 103 THR B CG2 1 ATOM 6178 N N . LEU B 2 82 ? -62.825 19.207 -9.318 1.00 53.34 ? 104 LEU B N 1 ATOM 6179 C CA . LEU B 2 82 ? -63.390 20.435 -9.862 1.00 54.01 ? 104 LEU B CA 1 ATOM 6180 C C . LEU B 2 82 ? -62.742 20.820 -11.192 1.00 57.39 ? 104 LEU B C 1 ATOM 6181 O O . LEU B 2 82 ? -63.381 21.444 -12.038 1.00 59.29 ? 104 LEU B O 1 ATOM 6182 C CB . LEU B 2 82 ? -63.297 21.585 -8.853 1.00 53.63 ? 104 LEU B CB 1 ATOM 6183 C CG . LEU B 2 82 ? -64.080 21.437 -7.544 1.00 54.54 ? 104 LEU B CG 1 ATOM 6184 C CD1 . LEU B 2 82 ? -64.520 22.796 -7.021 1.00 60.48 ? 104 LEU B CD1 1 ATOM 6185 C CD2 . LEU B 2 82 ? -65.282 20.521 -7.712 1.00 61.01 ? 104 LEU B CD2 1 ATOM 6186 N N . LYS B 2 83 ? -61.478 20.445 -11.376 1.00 53.87 ? 105 LYS B N 1 ATOM 6187 C CA . LYS B 2 83 ? -60.818 20.611 -12.667 1.00 55.93 ? 105 LYS B CA 1 ATOM 6188 C C . LYS B 2 83 ? -61.428 19.644 -13.674 1.00 56.82 ? 105 LYS B C 1 ATOM 6189 O O . LYS B 2 83 ? -61.687 20.006 -14.821 1.00 62.95 ? 105 LYS B O 1 ATOM 6190 C CB . LYS B 2 83 ? -59.310 20.369 -12.554 1.00 60.44 ? 105 LYS B CB 1 ATOM 6191 C CG . LYS B 2 83 ? -58.546 20.568 -13.859 1.00 58.50 ? 105 LYS B CG 1 ATOM 6192 C CD . LYS B 2 83 ? -58.803 21.953 -14.430 1.00 57.00 ? 105 LYS B CD 1 ATOM 6193 C CE . LYS B 2 83 ? -58.043 22.195 -15.724 1.00 55.21 ? 105 LYS B CE 1 ATOM 6194 N NZ . LYS B 2 83 ? -58.609 21.416 -16.857 1.00 60.62 ? 105 LYS B NZ 1 ATOM 6195 N N . GLY B 2 84 ? -61.661 18.412 -13.231 1.00 54.44 ? 106 GLY B N 1 ATOM 6196 C CA . GLY B 2 84 ? -62.278 17.401 -14.068 1.00 57.46 ? 106 GLY B CA 1 ATOM 6197 C C . GLY B 2 84 ? -63.711 17.740 -14.436 1.00 60.87 ? 106 GLY B C 1 ATOM 6198 O O . GLY B 2 84 ? -64.150 17.478 -15.556 1.00 59.10 ? 106 GLY B O 1 ATOM 6199 N N . LEU B 2 85 ? -64.444 18.318 -13.488 1.00 59.35 ? 107 LEU B N 1 ATOM 6200 C CA . LEU B 2 85 ? -65.819 18.738 -13.736 1.00 56.32 ? 107 LEU B CA 1 ATOM 6201 C C . LEU B 2 85 ? -65.868 19.790 -14.836 1.00 57.15 ? 107 LEU B C 1 ATOM 6202 O O . LEU B 2 85 ? -66.620 19.658 -15.800 1.00 62.81 ? 107 LEU B O 1 ATOM 6203 C CB . LEU B 2 85 ? -66.459 19.292 -12.461 1.00 52.64 ? 107 LEU B CB 1 ATOM 6204 C CG . LEU B 2 85 ? -67.909 19.767 -12.597 1.00 47.68 ? 107 LEU B CG 1 ATOM 6205 C CD1 . LEU B 2 85 ? -68.845 18.583 -12.766 1.00 47.34 ? 107 LEU B CD1 1 ATOM 6206 C CD2 . LEU B 2 85 ? -68.332 20.623 -11.412 1.00 44.87 ? 107 LEU B CD2 1 ATOM 6207 N N . THR B 2 86 ? -65.047 20.826 -14.691 1.00 54.13 ? 108 THR B N 1 ATOM 6208 C CA . THR B 2 86 ? -65.030 21.943 -15.631 1.00 55.22 ? 108 THR B CA 1 ATOM 6209 C C . THR B 2 86 ? -64.617 21.550 -17.049 1.00 62.51 ? 108 THR B C 1 ATOM 6210 O O . THR B 2 86 ? -64.841 22.306 -17.991 1.00 66.32 ? 108 THR B O 1 ATOM 6211 C CB . THR B 2 86 ? -64.125 23.085 -15.138 1.00 56.69 ? 108 THR B CB 1 ATOM 6212 O OG1 . THR B 2 86 ? -62.844 22.560 -14.773 1.00 61.84 ? 108 THR B OG1 1 ATOM 6213 C CG2 . THR B 2 86 ? -64.743 23.762 -13.933 1.00 64.63 ? 108 THR B CG2 1 ATOM 6214 N N . GLN B 2 87 ? -63.999 20.383 -17.196 1.00 64.47 ? 109 GLN B N 1 ATOM 6215 C CA . GLN B 2 87 ? -63.634 19.870 -18.516 1.00 65.27 ? 109 GLN B CA 1 ATOM 6216 C C . GLN B 2 87 ? -64.837 19.293 -19.264 1.00 68.78 ? 109 GLN B C 1 ATOM 6217 O O . GLN B 2 87 ? -65.064 19.611 -20.433 1.00 69.88 ? 109 GLN B O 1 ATOM 6218 C CB . GLN B 2 87 ? -62.536 18.809 -18.401 1.00 60.17 ? 109 GLN B CB 1 ATOM 6219 C CG . GLN B 2 87 ? -61.164 19.352 -18.019 1.00 60.60 ? 109 GLN B CG 1 ATOM 6220 C CD . GLN B 2 87 ? -60.517 20.150 -19.133 1.00 64.37 ? 109 GLN B CD 1 ATOM 6221 O OE1 . GLN B 2 87 ? -59.702 19.628 -19.895 1.00 67.00 ? 109 GLN B OE1 1 ATOM 6222 N NE2 . GLN B 2 87 ? -60.872 21.426 -19.231 1.00 62.43 ? 109 GLN B NE2 1 ATOM 6223 N N . SER B 2 88 ? -65.599 18.442 -18.582 1.00 65.14 ? 110 SER B N 1 ATOM 6224 C CA . SER B 2 88 ? -66.778 17.816 -19.172 1.00 63.37 ? 110 SER B CA 1 ATOM 6225 C C . SER B 2 88 ? -67.867 18.841 -19.468 1.00 67.08 ? 110 SER B C 1 ATOM 6226 O O . SER B 2 88 ? -68.572 18.737 -20.472 1.00 70.69 ? 110 SER B O 1 ATOM 6227 C CB . SER B 2 88 ? -67.320 16.721 -18.252 1.00 58.69 ? 110 SER B CB 1 ATOM 6228 O OG . SER B 2 88 ? -66.466 15.591 -18.238 1.00 51.94 ? 110 SER B OG 1 ATOM 6229 N N . VAL B 2 89 ? -68.000 19.829 -18.589 1.00 65.67 ? 111 VAL B N 1 ATOM 6230 C CA . VAL B 2 89 ? -68.976 20.895 -18.781 1.00 66.84 ? 111 VAL B CA 1 ATOM 6231 C C . VAL B 2 89 ? -68.348 22.083 -19.504 1.00 70.47 ? 111 VAL B C 1 ATOM 6232 O O . VAL B 2 89 ? -68.984 23.122 -19.673 1.00 75.63 ? 111 VAL B O 1 ATOM 6233 C CB . VAL B 2 89 ? -69.584 21.376 -17.443 1.00 60.10 ? 111 VAL B CB 1 ATOM 6234 C CG1 . VAL B 2 89 ? -70.115 20.198 -16.645 1.00 54.00 ? 111 VAL B CG1 1 ATOM 6235 C CG2 . VAL B 2 89 ? -68.558 22.146 -16.633 1.00 63.40 ? 111 VAL B CG2 1 ATOM 6236 N N . GLY B 2 90 ? -67.092 21.935 -19.911 1.00 66.45 ? 112 GLY B N 1 ATOM 6237 C CA . GLY B 2 90 ? -66.387 23.001 -20.600 1.00 68.56 ? 112 GLY B CA 1 ATOM 6238 C C . GLY B 2 90 ? -66.180 22.777 -22.087 1.00 67.82 ? 112 GLY B C 1 ATOM 6239 O O . GLY B 2 90 ? -65.505 23.571 -22.744 1.00 69.60 ? 112 GLY B O 1 ATOM 6240 N N . GLU B 2 91 ? -66.758 21.703 -22.618 1.00 67.00 ? 113 GLU B N 1 ATOM 6241 C CA . GLU B 2 91 ? -66.588 21.361 -24.029 1.00 73.82 ? 113 GLU B CA 1 ATOM 6242 C C . GLU B 2 91 ? -67.191 22.419 -24.948 1.00 85.05 ? 113 GLU B C 1 ATOM 6243 O O . GLU B 2 91 ? -68.097 23.154 -24.556 1.00 90.95 ? 113 GLU B O 1 ATOM 6244 C CB . GLU B 2 91 ? -67.204 19.994 -24.342 1.00 74.90 ? 113 GLU B CB 1 ATOM 6245 C CG . GLU B 2 91 ? -66.489 18.809 -23.714 1.00 68.77 ? 113 GLU B CG 1 ATOM 6246 C CD . GLU B 2 91 ? -66.962 17.478 -24.275 1.00 76.30 ? 113 GLU B CD 1 ATOM 6247 O OE1 . GLU B 2 91 ? -67.017 16.493 -23.509 1.00 73.01 ? 113 GLU B OE1 1 ATOM 6248 O OE2 . GLU B 2 91 ? -67.273 17.415 -25.483 1.00 82.91 ? 113 GLU B OE2 1 ATOM 6249 N N . GLU B 2 92 ? -66.683 22.483 -26.174 1.00 83.83 ? 114 GLU B N 1 ATOM 6250 C CA . GLU B 2 92 ? -67.148 23.458 -27.153 1.00 86.85 ? 114 GLU B CA 1 ATOM 6251 C C . GLU B 2 92 ? -68.531 23.088 -27.678 1.00 89.55 ? 114 GLU B C 1 ATOM 6252 O O . GLU B 2 92 ? -69.347 23.960 -27.978 1.00 90.89 ? 114 GLU B O 1 ATOM 6253 C CB . GLU B 2 92 ? -66.158 23.551 -28.315 1.00 90.05 ? 114 GLU B CB 1 ATOM 6254 C CG . GLU B 2 92 ? -64.705 23.665 -27.883 1.00 92.60 ? 114 GLU B CG 1 ATOM 6255 C CD . GLU B 2 92 ? -64.420 24.933 -27.101 1.00 92.93 ? 114 GLU B CD 1 ATOM 6256 O OE1 . GLU B 2 92 ? -65.047 25.969 -27.395 1.00 90.54 ? 114 GLU B OE1 1 ATOM 6257 O OE2 . GLU B 2 92 ? -63.566 24.893 -26.192 1.00 95.07 ? 114 GLU B OE2 1 ATOM 6258 N N . HIS B 2 93 ? -68.784 21.788 -27.786 1.00 90.83 ? 115 HIS B N 1 ATOM 6259 C CA . HIS B 2 93 ? -70.059 21.282 -28.277 1.00 92.38 ? 115 HIS B CA 1 ATOM 6260 C C . HIS B 2 93 ? -71.192 21.564 -27.293 1.00 86.18 ? 115 HIS B C 1 ATOM 6261 O O . HIS B 2 93 ? -72.332 21.793 -27.694 1.00 86.28 ? 115 HIS B O 1 ATOM 6262 C CB . HIS B 2 93 ? -69.959 19.779 -28.543 1.00 94.17 ? 115 HIS B CB 1 ATOM 6263 C CG . HIS B 2 93 ? -68.840 19.404 -29.464 1.00 98.33 ? 115 HIS B CG 1 ATOM 6264 N ND1 . HIS B 2 93 ? -68.303 18.135 -29.502 1.00 104.50 ? 115 HIS B ND1 1 ATOM 6265 C CD2 . HIS B 2 93 ? -68.159 20.129 -30.382 1.00 101.25 ? 115 HIS B CD2 1 ATOM 6266 C CE1 . HIS B 2 93 ? -67.337 18.095 -30.404 1.00 115.25 ? 115 HIS B CE1 1 ATOM 6267 N NE2 . HIS B 2 93 ? -67.230 19.293 -30.952 1.00 114.70 ? 115 HIS B NE2 1 ATOM 6268 N N . LYS B 2 94 ? -70.873 21.542 -26.003 1.00 83.70 ? 116 LYS B N 1 ATOM 6269 C CA . LYS B 2 94 ? -71.857 21.837 -24.968 1.00 79.42 ? 116 LYS B CA 1 ATOM 6270 C C . LYS B 2 94 ? -72.264 23.309 -24.990 1.00 84.02 ? 116 LYS B C 1 ATOM 6271 O O . LYS B 2 94 ? -71.460 24.179 -25.329 1.00 82.06 ? 116 LYS B O 1 ATOM 6272 C CB . LYS B 2 94 ? -71.308 21.472 -23.587 1.00 73.55 ? 116 LYS B CB 1 ATOM 6273 C CG . LYS B 2 94 ? -71.784 20.136 -23.035 1.00 70.91 ? 116 LYS B CG 1 ATOM 6274 C CD . LYS B 2 94 ? -70.871 18.993 -23.445 1.00 67.95 ? 116 LYS B CD 1 ATOM 6275 C CE . LYS B 2 94 ? -71.222 17.719 -22.691 1.00 68.32 ? 116 LYS B CE 1 ATOM 6276 N NZ . LYS B 2 94 ? -70.273 16.610 -22.989 1.00 77.39 ? 116 LYS B NZ 1 ATOM 6277 N N . SER B 2 95 ? -73.515 23.579 -24.625 1.00 89.77 ? 117 SER B N 1 ATOM 6278 C CA . SER B 2 95 ? -74.028 24.945 -24.552 1.00 90.47 ? 117 SER B CA 1 ATOM 6279 C C . SER B 2 95 ? -75.195 25.038 -23.569 1.00 93.72 ? 117 SER B C 1 ATOM 6280 O O . SER B 2 95 ? -75.468 24.093 -22.829 1.00 91.95 ? 117 SER B O 1 ATOM 6281 C CB . SER B 2 95 ? -74.445 25.449 -25.936 1.00 92.97 ? 117 SER B CB 1 ATOM 6282 O OG . SER B 2 95 ? -75.445 24.621 -26.502 1.00 112.01 ? 117 SER B OG 1 ATOM 6283 N N . GLY B 2 96 ? -75.876 26.180 -23.564 1.00 100.25 ? 118 GLY B N 1 ATOM 6284 C CA . GLY B 2 96 ? -77.006 26.397 -22.676 1.00 105.52 ? 118 GLY B CA 1 ATOM 6285 C C . GLY B 2 96 ? -76.686 27.321 -21.516 1.00 101.48 ? 118 GLY B C 1 ATOM 6286 O O . GLY B 2 96 ? -75.540 27.402 -21.073 1.00 99.58 ? 118 GLY B O 1 ATOM 6287 N N . ASP B 2 97 ? -77.709 28.010 -21.014 1.00 93.84 ? 119 ASP B N 1 ATOM 6288 C CA . ASP B 2 97 ? -77.531 29.008 -19.961 1.00 96.29 ? 119 ASP B CA 1 ATOM 6289 C C . ASP B 2 97 ? -77.379 28.389 -18.573 1.00 98.05 ? 119 ASP B C 1 ATOM 6290 O O . ASP B 2 97 ? -76.941 29.055 -17.634 1.00 94.83 ? 119 ASP B O 1 ATOM 6291 C CB . ASP B 2 97 ? -78.686 30.014 -19.972 1.00 97.67 ? 119 ASP B CB 1 ATOM 6292 C CG . ASP B 2 97 ? -78.298 31.339 -20.603 1.00 94.36 ? 119 ASP B CG 1 ATOM 6293 O OD1 . ASP B 2 97 ? -77.160 31.798 -20.369 1.00 87.72 ? 119 ASP B OD1 1 ATOM 6294 O OD2 . ASP B 2 97 ? -79.129 31.923 -21.330 1.00 96.29 ? 119 ASP B OD2 1 ATOM 6295 N N . ILE B 2 98 ? -77.746 27.117 -18.447 1.00 98.86 ? 120 ILE B N 1 ATOM 6296 C CA . ILE B 2 98 ? -77.534 26.382 -17.207 1.00 93.41 ? 120 ILE B CA 1 ATOM 6297 C C . ILE B 2 98 ? -76.037 26.226 -16.992 1.00 97.74 ? 120 ILE B C 1 ATOM 6298 O O . ILE B 2 98 ? -75.528 26.391 -15.883 1.00 98.55 ? 120 ILE B O 1 ATOM 6299 C CB . ILE B 2 98 ? -78.151 24.975 -17.276 1.00 88.02 ? 120 ILE B CB 1 ATOM 6300 C CG1 . ILE B 2 98 ? -79.453 24.993 -18.082 1.00 100.21 ? 120 ILE B CG1 1 ATOM 6301 C CG2 . ILE B 2 98 ? -78.361 24.419 -15.874 1.00 72.11 ? 120 ILE B CG2 1 ATOM 6302 C CD1 . ILE B 2 98 ? -79.927 23.618 -18.514 1.00 97.61 ? 120 ILE B CD1 1 ATOM 6303 N N . ARG B 2 99 ? -75.342 25.913 -18.081 1.00 95.97 ? 121 ARG B N 1 ATOM 6304 C CA . ARG B 2 99 ? -73.907 25.663 -18.065 1.00 86.72 ? 121 ARG B CA 1 ATOM 6305 C C . ARG B 2 99 ? -73.108 26.938 -17.837 1.00 86.97 ? 121 ARG B C 1 ATOM 6306 O O . ARG B 2 99 ? -72.120 26.936 -17.104 1.00 87.18 ? 121 ARG B O 1 ATOM 6307 C CB . ARG B 2 99 ? -73.494 25.019 -19.386 1.00 81.69 ? 121 ARG B CB 1 ATOM 6308 C CG . ARG B 2 99 ? -72.049 24.575 -19.473 1.00 84.36 ? 121 ARG B CG 1 ATOM 6309 C CD . ARG B 2 99 ? -71.930 23.571 -20.604 1.00 86.35 ? 121 ARG B CD 1 ATOM 6310 N NE . ARG B 2 99 ? -70.926 23.908 -21.611 1.00 82.93 ? 121 ARG B NE 1 ATOM 6311 C CZ . ARG B 2 99 ? -70.970 24.973 -22.405 1.00 83.53 ? 121 ARG B CZ 1 ATOM 6312 N NH1 . ARG B 2 99 ? -71.949 25.861 -22.300 1.00 93.93 ? 121 ARG B NH1 1 ATOM 6313 N NH2 . ARG B 2 99 ? -70.013 25.160 -23.301 1.00 81.17 ? 121 ARG B NH2 1 ATOM 6314 N N . ASP B 2 100 ? -73.536 28.025 -18.471 1.00 88.72 ? 122 ASP B N 1 ATOM 6315 C CA . ASP B 2 100 ? -72.865 29.311 -18.317 1.00 92.27 ? 122 ASP B CA 1 ATOM 6316 C C . ASP B 2 100 ? -72.910 29.791 -16.866 1.00 88.48 ? 122 ASP B C 1 ATOM 6317 O O . ASP B 2 100 ? -72.033 30.527 -16.420 1.00 85.55 ? 122 ASP B O 1 ATOM 6318 C CB . ASP B 2 100 ? -73.476 30.355 -19.256 1.00 99.50 ? 122 ASP B CB 1 ATOM 6319 C CG . ASP B 2 100 ? -73.248 30.028 -20.722 1.00 96.81 ? 122 ASP B CG 1 ATOM 6320 O OD1 . ASP B 2 100 ? -72.226 29.383 -21.040 1.00 95.39 ? 122 ASP B OD1 1 ATOM 6321 O OD2 . ASP B 2 100 ? -74.090 30.420 -21.558 1.00 94.49 ? 122 ASP B OD2 1 ATOM 6322 N N . ALA B 2 101 ? -73.930 29.358 -16.132 1.00 87.50 ? 123 ALA B N 1 ATOM 6323 C CA . ALA B 2 101 ? -74.053 29.688 -14.717 1.00 85.66 ? 123 ALA B CA 1 ATOM 6324 C C . ALA B 2 101 ? -73.116 28.828 -13.868 1.00 85.42 ? 123 ALA B C 1 ATOM 6325 O O . ALA B 2 101 ? -72.693 29.236 -12.786 1.00 84.81 ? 123 ALA B O 1 ATOM 6326 C CB . ALA B 2 101 ? -75.491 29.522 -14.258 1.00 82.28 ? 123 ALA B CB 1 ATOM 6327 N N . LEU B 2 102 ? -72.803 27.636 -14.367 1.00 82.47 ? 124 LEU B N 1 ATOM 6328 C CA . LEU B 2 102 ? -71.907 26.713 -13.676 1.00 77.25 ? 124 LEU B CA 1 ATOM 6329 C C . LEU B 2 102 ? -70.481 27.257 -13.626 1.00 77.04 ? 124 LEU B C 1 ATOM 6330 O O . LEU B 2 102 ? -69.889 27.381 -12.554 1.00 73.38 ? 124 LEU B O 1 ATOM 6331 C CB . LEU B 2 102 ? -71.912 25.350 -14.376 1.00 66.22 ? 124 LEU B CB 1 ATOM 6332 C CG . LEU B 2 102 ? -72.322 24.104 -13.590 1.00 61.72 ? 124 LEU B CG 1 ATOM 6333 C CD1 . LEU B 2 102 ? -72.042 22.857 -14.410 1.00 61.28 ? 124 LEU B CD1 1 ATOM 6334 C CD2 . LEU B 2 102 ? -71.591 24.041 -12.270 1.00 62.13 ? 124 LEU B CD2 1 ATOM 6335 N N . LEU B 2 103 ? -69.944 27.588 -14.797 1.00 76.38 ? 125 LEU B N 1 ATOM 6336 C CA . LEU B 2 103 ? -68.556 28.017 -14.936 1.00 73.36 ? 125 LEU B CA 1 ATOM 6337 C C . LEU B 2 103 ? -68.277 29.352 -14.245 1.00 79.31 ? 125 LEU B C 1 ATOM 6338 O O . LEU B 2 103 ? -67.228 29.526 -13.626 1.00 84.97 ? 125 LEU B O 1 ATOM 6339 C CB . LEU B 2 103 ? -68.190 28.109 -16.418 1.00 70.69 ? 125 LEU B CB 1 ATOM 6340 C CG . LEU B 2 103 ? -68.626 26.921 -17.278 1.00 64.32 ? 125 LEU B CG 1 ATOM 6341 C CD1 . LEU B 2 103 ? -68.502 27.244 -18.758 1.00 68.26 ? 125 LEU B CD1 1 ATOM 6342 C CD2 . LEU B 2 103 ? -67.816 25.685 -16.934 1.00 61.14 ? 125 LEU B CD2 1 ATOM 6343 N N . ASP B 2 104 ? -69.214 30.290 -14.366 1.00 80.17 ? 126 ASP B N 1 ATOM 6344 C CA . ASP B 2 104 ? -69.084 31.599 -13.732 1.00 82.16 ? 126 ASP B CA 1 ATOM 6345 C C . ASP B 2 104 ? -68.924 31.448 -12.225 1.00 81.41 ? 126 ASP B C 1 ATOM 6346 O O . ASP B 2 104 ? -68.127 32.152 -11.599 1.00 79.84 ? 126 ASP B O 1 ATOM 6347 C CB . ASP B 2 104 ? -70.296 32.482 -14.048 1.00 95.90 ? 126 ASP B CB 1 ATOM 6348 C CG . ASP B 2 104 ? -70.369 32.874 -15.513 1.00 99.56 ? 126 ASP B CG 1 ATOM 6349 O OD1 . ASP B 2 104 ? -69.341 32.766 -16.213 1.00 98.58 ? 126 ASP B OD1 1 ATOM 6350 O OD2 . ASP B 2 104 ? -71.456 33.299 -15.962 1.00 101.29 ? 126 ASP B OD2 1 ATOM 6351 N N . ALA B 2 105 ? -69.684 30.523 -11.650 1.00 80.80 ? 127 ALA B N 1 ATOM 6352 C CA . ALA B 2 105 ? -69.557 30.201 -10.235 1.00 86.13 ? 127 ALA B CA 1 ATOM 6353 C C . ALA B 2 105 ? -68.338 29.313 -10.009 1.00 82.29 ? 127 ALA B C 1 ATOM 6354 O O . ALA B 2 105 ? -67.738 29.327 -8.935 1.00 85.30 ? 127 ALA B O 1 ATOM 6355 C CB . ALA B 2 105 ? -70.819 29.507 -9.735 1.00 77.85 ? 127 ALA B CB 1 ATOM 6356 N N . LEU B 2 106 ? -67.969 28.550 -11.035 1.00 74.31 ? 128 LEU B N 1 ATOM 6357 C CA . LEU B 2 106 ? -66.812 27.666 -10.953 1.00 69.89 ? 128 LEU B CA 1 ATOM 6358 C C . LEU B 2 106 ? -65.498 28.384 -11.255 1.00 75.97 ? 128 LEU B C 1 ATOM 6359 O O . LEU B 2 106 ? -64.425 27.844 -11.004 1.00 75.20 ? 128 LEU B O 1 ATOM 6360 C CB . LEU B 2 106 ? -66.982 26.455 -11.877 1.00 67.25 ? 128 LEU B CB 1 ATOM 6361 C CG . LEU B 2 106 ? -67.614 25.208 -11.260 1.00 60.96 ? 128 LEU B CG 1 ATOM 6362 C CD1 . LEU B 2 106 ? -67.937 24.179 -12.330 1.00 58.53 ? 128 LEU B CD1 1 ATOM 6363 C CD2 . LEU B 2 106 ? -66.682 24.615 -10.220 1.00 54.66 ? 128 LEU B CD2 1 ATOM 6364 N N . SER B 2 107 ? -65.590 29.594 -11.799 1.00 82.44 ? 129 SER B N 1 ATOM 6365 C CA . SER B 2 107 ? -64.413 30.396 -12.135 1.00 77.66 ? 129 SER B CA 1 ATOM 6366 C C . SER B 2 107 ? -63.507 30.661 -10.933 1.00 78.51 ? 129 SER B C 1 ATOM 6367 O O . SER B 2 107 ? -62.369 30.192 -10.883 1.00 80.71 ? 129 SER B O 1 ATOM 6368 C CB . SER B 2 107 ? -64.837 31.726 -12.766 1.00 79.35 ? 129 SER B CB 1 ATOM 6369 O OG . SER B 2 107 ? -63.804 32.690 -12.671 1.00 75.74 ? 129 SER B OG 1 ATOM 6370 N N . GLY B 2 108 ? -64.026 31.413 -9.969 1.00 78.34 ? 130 GLY B N 1 ATOM 6371 C CA . GLY B 2 108 ? -63.250 31.851 -8.824 1.00 77.93 ? 130 GLY B CA 1 ATOM 6372 C C . GLY B 2 108 ? -63.354 30.971 -7.593 1.00 78.91 ? 130 GLY B C 1 ATOM 6373 O O . GLY B 2 108 ? -63.159 31.450 -6.477 1.00 86.66 ? 130 GLY B O 1 ATOM 6374 N N . VAL B 2 109 ? -63.682 29.696 -7.791 1.00 74.31 ? 131 VAL B N 1 ATOM 6375 C CA . VAL B 2 109 ? -63.872 28.750 -6.689 1.00 74.06 ? 131 VAL B CA 1 ATOM 6376 C C . VAL B 2 109 ? -62.749 28.765 -5.649 1.00 79.62 ? 131 VAL B C 1 ATOM 6377 O O . VAL B 2 109 ? -63.010 28.850 -4.448 1.00 90.73 ? 131 VAL B O 1 ATOM 6378 C CB . VAL B 2 109 ? -64.049 27.308 -7.217 1.00 70.77 ? 131 VAL B CB 1 ATOM 6379 C CG1 . VAL B 2 109 ? -63.742 26.286 -6.131 1.00 64.88 ? 131 VAL B CG1 1 ATOM 6380 C CG2 . VAL B 2 109 ? -65.453 27.116 -7.750 1.00 74.20 ? 131 VAL B CG2 1 ATOM 6381 N N . TRP B 2 110 ? -61.506 28.698 -6.111 1.00 75.51 ? 132 TRP B N 1 ATOM 6382 C CA . TRP B 2 110 ? -60.368 28.596 -5.204 1.00 78.08 ? 132 TRP B CA 1 ATOM 6383 C C . TRP B 2 110 ? -59.756 29.943 -4.829 1.00 82.86 ? 132 TRP B C 1 ATOM 6384 O O . TRP B 2 110 ? -58.830 29.996 -4.020 1.00 92.55 ? 132 TRP B O 1 ATOM 6385 C CB . TRP B 2 110 ? -59.288 27.694 -5.807 1.00 80.76 ? 132 TRP B CB 1 ATOM 6386 C CG . TRP B 2 110 ? -59.796 26.364 -6.262 1.00 74.26 ? 132 TRP B CG 1 ATOM 6387 C CD1 . TRP B 2 110 ? -59.799 25.880 -7.537 1.00 70.59 ? 132 TRP B CD1 1 ATOM 6388 C CD2 . TRP B 2 110 ? -60.383 25.346 -5.445 1.00 74.67 ? 132 TRP B CD2 1 ATOM 6389 N NE1 . TRP B 2 110 ? -60.346 24.621 -7.566 1.00 67.57 ? 132 TRP B NE1 1 ATOM 6390 C CE2 . TRP B 2 110 ? -60.714 24.270 -6.293 1.00 71.51 ? 132 TRP B CE2 1 ATOM 6391 C CE3 . TRP B 2 110 ? -60.659 25.237 -4.080 1.00 73.93 ? 132 TRP B CE3 1 ATOM 6392 C CZ2 . TRP B 2 110 ? -61.306 23.103 -5.818 1.00 69.65 ? 132 TRP B CZ2 1 ATOM 6393 C CZ3 . TRP B 2 110 ? -61.248 24.079 -3.612 1.00 70.20 ? 132 TRP B CZ3 1 ATOM 6394 C CH2 . TRP B 2 110 ? -61.565 23.028 -4.477 1.00 69.08 ? 132 TRP B CH2 1 ATOM 6395 N N . VAL B 2 111 ? -60.274 31.019 -5.417 1.00 81.01 ? 133 VAL B N 1 ATOM 6396 C CA . VAL B 2 111 ? -59.717 32.363 -5.241 1.00 86.77 ? 133 VAL B CA 1 ATOM 6397 C C . VAL B 2 111 ? -59.461 32.731 -3.779 1.00 88.73 ? 133 VAL B C 1 ATOM 6398 O O . VAL B 2 111 ? -58.398 33.250 -3.433 1.00 91.84 ? 133 VAL B O 1 ATOM 6399 C CB . VAL B 2 111 ? -60.626 33.431 -5.901 1.00 89.18 ? 133 VAL B CB 1 ATOM 6400 C CG1 . VAL B 2 111 ? -60.428 34.797 -5.259 1.00 93.26 ? 133 VAL B CG1 1 ATOM 6401 C CG2 . VAL B 2 111 ? -60.373 33.493 -7.400 1.00 95.46 ? 133 VAL B CG2 1 ATOM 6402 N N . ASP B 2 112 ? -60.432 32.439 -2.922 1.00 90.47 ? 134 ASP B N 1 ATOM 6403 C CA . ASP B 2 112 ? -60.348 32.811 -1.517 1.00 98.83 ? 134 ASP B CA 1 ATOM 6404 C C . ASP B 2 112 ? -59.615 31.778 -0.652 1.00 91.91 ? 134 ASP B C 1 ATOM 6405 O O . ASP B 2 112 ? -59.206 32.085 0.467 1.00 91.56 ? 134 ASP B O 1 ATOM 6406 C CB . ASP B 2 112 ? -61.758 33.065 -0.967 1.00 107.88 ? 134 ASP B CB 1 ATOM 6407 C CG . ASP B 2 112 ? -61.770 34.048 0.191 1.00 114.63 ? 134 ASP B CG 1 ATOM 6408 O OD1 . ASP B 2 112 ? -60.767 34.768 0.380 1.00 118.31 ? 134 ASP B OD1 1 ATOM 6409 O OD2 . ASP B 2 112 ? -62.793 34.110 0.904 1.00 111.66 ? 134 ASP B OD2 1 ATOM 6410 N N . SER B 2 113 ? -59.431 30.566 -1.173 1.00 84.82 ? 135 SER B N 1 ATOM 6411 C CA . SER B 2 113 ? -58.916 29.460 -0.359 1.00 78.11 ? 135 SER B CA 1 ATOM 6412 C C . SER B 2 113 ? -57.422 29.184 -0.521 1.00 81.62 ? 135 SER B C 1 ATOM 6413 O O . SER B 2 113 ? -56.740 29.834 -1.313 1.00 83.72 ? 135 SER B O 1 ATOM 6414 C CB . SER B 2 113 ? -59.719 28.180 -0.615 1.00 75.71 ? 135 SER B CB 1 ATOM 6415 O OG . SER B 2 113 ? -59.815 27.901 -2.000 1.00 76.93 ? 135 SER B OG 1 ATOM 6416 N N . THR B 2 114 ? -56.930 28.202 0.234 1.00 85.54 ? 136 THR B N 1 ATOM 6417 C CA . THR B 2 114 ? -55.504 27.883 0.279 1.00 88.43 ? 136 THR B CA 1 ATOM 6418 C C . THR B 2 114 ? -55.000 27.247 -1.019 1.00 85.18 ? 136 THR B C 1 ATOM 6419 O O . THR B 2 114 ? -55.592 26.291 -1.519 1.00 84.14 ? 136 THR B O 1 ATOM 6420 C CB . THR B 2 114 ? -55.165 26.964 1.478 1.00 72.06 ? 136 THR B CB 1 ATOM 6421 O OG1 . THR B 2 114 ? -55.809 25.694 1.316 1.00 70.46 ? 136 THR B OG1 1 ATOM 6422 C CG2 . THR B 2 114 ? -55.628 27.599 2.781 1.00 64.09 ? 136 THR B CG2 1 ATOM 6423 N N . PRO B 2 115 ? -53.895 27.782 -1.563 1.00 78.80 ? 137 PRO B N 1 ATOM 6424 C CA . PRO B 2 115 ? -53.327 27.345 -2.844 1.00 79.52 ? 137 PRO B CA 1 ATOM 6425 C C . PRO B 2 115 ? -52.902 25.878 -2.844 1.00 81.97 ? 137 PRO B C 1 ATOM 6426 O O . PRO B 2 115 ? -52.707 25.290 -1.781 1.00 76.91 ? 137 PRO B O 1 ATOM 6427 C CB . PRO B 2 115 ? -52.093 28.240 -2.999 1.00 82.13 ? 137 PRO B CB 1 ATOM 6428 C CG . PRO B 2 115 ? -52.395 29.446 -2.184 1.00 77.99 ? 137 PRO B CG 1 ATOM 6429 C CD . PRO B 2 115 ? -53.164 28.934 -1.005 1.00 79.58 ? 137 PRO B CD 1 ATOM 6430 N N . SER B 2 116 ? -52.757 25.303 -4.035 1.00 83.09 ? 138 SER B N 1 ATOM 6431 C CA . SER B 2 116 ? -52.349 23.909 -4.180 1.00 75.27 ? 138 SER B CA 1 ATOM 6432 C C . SER B 2 116 ? -50.871 23.719 -3.847 1.00 77.60 ? 138 SER B C 1 ATOM 6433 O O . SER B 2 116 ? -50.191 24.665 -3.451 1.00 79.75 ? 138 SER B O 1 ATOM 6434 C CB . SER B 2 116 ? -52.648 23.407 -5.594 1.00 68.01 ? 138 SER B CB 1 ATOM 6435 O OG . SER B 2 116 ? -52.239 24.351 -6.566 1.00 71.26 ? 138 SER B OG 1 ATOM 6436 N N . SER B 2 117 ? -50.381 22.493 -4.003 1.00 77.91 ? 139 SER B N 1 ATOM 6437 C CA . SER B 2 117 ? -49.008 22.161 -3.627 1.00 84.65 ? 139 SER B CA 1 ATOM 6438 C C . SER B 2 117 ? -47.953 22.666 -4.603 1.00 84.42 ? 139 SER B C 1 ATOM 6439 O O . SER B 2 117 ? -48.099 22.540 -5.816 1.00 79.78 ? 139 SER B O 1 ATOM 6440 C CB . SER B 2 117 ? -48.846 20.651 -3.444 1.00 75.79 ? 139 SER B CB 1 ATOM 6441 O OG . SER B 2 117 ? -49.137 20.267 -2.115 1.00 83.42 ? 139 SER B OG 1 ATOM 6442 N N . THR B 2 118 ? -46.901 23.265 -4.056 1.00 86.05 ? 140 THR B N 1 ATOM 6443 C CA . THR B 2 118 ? -45.696 23.559 -4.817 1.00 86.19 ? 140 THR B CA 1 ATOM 6444 C C . THR B 2 118 ? -44.651 22.481 -4.551 1.00 84.51 ? 140 THR B C 1 ATOM 6445 O O . THR B 2 118 ? -43.542 22.533 -5.082 1.00 90.36 ? 140 THR B O 1 ATOM 6446 C CB . THR B 2 118 ? -45.105 24.931 -4.444 1.00 88.89 ? 140 THR B CB 1 ATOM 6447 O OG1 . THR B 2 118 ? -44.816 24.961 -3.041 1.00 85.49 ? 140 THR B OG1 1 ATOM 6448 C CG2 . THR B 2 118 ? -46.083 26.048 -4.783 1.00 94.18 ? 140 THR B CG2 1 ATOM 6449 N N . ASN B 2 119 ? -45.018 21.501 -3.728 1.00 79.86 ? 141 ASN B N 1 ATOM 6450 C CA . ASN B 2 119 ? -44.070 20.504 -3.235 1.00 83.33 ? 141 ASN B CA 1 ATOM 6451 C C . ASN B 2 119 ? -43.611 19.500 -4.287 1.00 78.71 ? 141 ASN B C 1 ATOM 6452 O O . ASN B 2 119 ? -44.002 19.571 -5.452 1.00 76.15 ? 141 ASN B O 1 ATOM 6453 C CB . ASN B 2 119 ? -44.656 19.744 -2.041 1.00 79.44 ? 141 ASN B CB 1 ATOM 6454 C CG . ASN B 2 119 ? -45.039 20.656 -0.894 1.00 85.19 ? 141 ASN B CG 1 ATOM 6455 O OD1 . ASN B 2 119 ? -44.179 21.151 -0.166 1.00 90.78 ? 141 ASN B OD1 1 ATOM 6456 N ND2 . ASN B 2 119 ? -46.338 20.867 -0.714 1.00 84.15 ? 141 ASN B ND2 1 ATOM 6457 N N . ILE B 2 120 ? -42.781 18.556 -3.852 1.00 72.22 ? 142 ILE B N 1 ATOM 6458 C CA . ILE B 2 120 ? -42.234 17.534 -4.731 1.00 64.74 ? 142 ILE B CA 1 ATOM 6459 C C . ILE B 2 120 ? -42.607 16.167 -4.166 1.00 64.78 ? 142 ILE B C 1 ATOM 6460 O O . ILE B 2 120 ? -42.572 15.969 -2.952 1.00 71.99 ? 142 ILE B O 1 ATOM 6461 C CB . ILE B 2 120 ? -40.695 17.670 -4.810 1.00 66.41 ? 142 ILE B CB 1 ATOM 6462 C CG1 . ILE B 2 120 ? -40.313 19.057 -5.338 1.00 75.77 ? 142 ILE B CG1 1 ATOM 6463 C CG2 . ILE B 2 120 ? -40.081 16.571 -5.665 1.00 66.39 ? 142 ILE B CG2 1 ATOM 6464 C CD1 . ILE B 2 120 ? -38.822 19.279 -5.485 1.00 91.82 ? 142 ILE B CD1 1 ATOM 6465 N N . PRO B 2 121 ? -42.979 15.218 -5.042 1.00 58.42 ? 143 PRO B N 1 ATOM 6466 C CA . PRO B 2 121 ? -43.344 13.881 -4.563 1.00 57.19 ? 143 PRO B CA 1 ATOM 6467 C C . PRO B 2 121 ? -42.136 13.140 -4.017 1.00 62.07 ? 143 PRO B C 1 ATOM 6468 O O . PRO B 2 121 ? -41.048 13.266 -4.575 1.00 60.61 ? 143 PRO B O 1 ATOM 6469 C CB . PRO B 2 121 ? -43.858 13.180 -5.826 1.00 54.92 ? 143 PRO B CB 1 ATOM 6470 C CG . PRO B 2 121 ? -43.305 13.969 -6.966 1.00 58.39 ? 143 PRO B CG 1 ATOM 6471 C CD . PRO B 2 121 ? -43.255 15.381 -6.479 1.00 61.09 ? 143 PRO B CD 1 ATOM 6472 N N . GLU B 2 122 ? -42.327 12.385 -2.940 1.00 74.10 ? 144 GLU B N 1 ATOM 6473 C CA . GLU B 2 122 ? -41.241 11.607 -2.358 1.00 79.70 ? 144 GLU B CA 1 ATOM 6474 C C . GLU B 2 122 ? -40.831 10.492 -3.311 1.00 74.03 ? 144 GLU B C 1 ATOM 6475 O O . GLU B 2 122 ? -41.597 10.104 -4.192 1.00 69.96 ? 144 GLU B O 1 ATOM 6476 C CB . GLU B 2 122 ? -41.646 11.033 -0.997 1.00 88.77 ? 144 GLU B CB 1 ATOM 6477 C CG . GLU B 2 122 ? -41.590 12.038 0.149 1.00 100.06 ? 144 GLU B CG 1 ATOM 6478 C CD . GLU B 2 122 ? -42.246 11.521 1.418 1.00 116.99 ? 144 GLU B CD 1 ATOM 6479 O OE1 . GLU B 2 122 ? -43.403 11.053 1.345 1.00 119.50 ? 144 GLU B OE1 1 ATOM 6480 O OE2 . GLU B 2 122 ? -41.605 11.581 2.489 1.00 113.19 ? 144 GLU B OE2 1 ATOM 6481 N N . ASN B 2 123 ? -39.619 9.982 -3.131 1.00 74.97 ? 145 ASN B N 1 ATOM 6482 C CA . ASN B 2 123 ? -39.067 8.979 -4.034 1.00 70.33 ? 145 ASN B CA 1 ATOM 6483 C C . ASN B 2 123 ? -39.662 7.592 -3.798 1.00 71.09 ? 145 ASN B C 1 ATOM 6484 O O . ASN B 2 123 ? -40.609 7.437 -3.027 1.00 64.77 ? 145 ASN B O 1 ATOM 6485 C CB . ASN B 2 123 ? -37.542 8.947 -3.916 1.00 69.58 ? 145 ASN B CB 1 ATOM 6486 C CG . ASN B 2 123 ? -36.923 10.330 -4.027 1.00 73.60 ? 145 ASN B CG 1 ATOM 6487 O OD1 . ASN B 2 123 ? -37.630 11.339 -4.044 1.00 70.42 ? 145 ASN B OD1 1 ATOM 6488 N ND2 . ASN B 2 123 ? -35.599 10.384 -4.092 1.00 79.89 ? 145 ASN B ND2 1 ATOM 6489 N N . GLY B 2 124 ? -39.102 6.586 -4.462 1.00 72.22 ? 146 GLY B N 1 ATOM 6490 C CA . GLY B 2 124 ? -39.658 5.243 -4.430 1.00 72.97 ? 146 GLY B CA 1 ATOM 6491 C C . GLY B 2 124 ? -40.283 4.859 -5.759 1.00 68.52 ? 146 GLY B C 1 ATOM 6492 O O . GLY B 2 124 ? -40.656 5.728 -6.548 1.00 60.52 ? 146 GLY B O 1 ATOM 6493 N N . CYS B 2 125 ? -40.388 3.557 -6.015 1.00 64.28 ? 147 CYS B N 1 ATOM 6494 C CA . CYS B 2 125 ? -40.942 3.070 -7.272 1.00 52.15 ? 147 CYS B CA 1 ATOM 6495 C C . CYS B 2 125 ? -42.417 3.422 -7.364 1.00 53.17 ? 147 CYS B C 1 ATOM 6496 O O . CYS B 2 125 ? -43.059 3.687 -6.351 1.00 52.25 ? 147 CYS B O 1 ATOM 6497 C CB . CYS B 2 125 ? -40.774 1.554 -7.388 1.00 49.16 ? 147 CYS B CB 1 ATOM 6498 S SG . CYS B 2 125 ? -39.102 0.949 -7.098 1.00 60.24 ? 147 CYS B SG 1 ATOM 6499 N N . VAL B 2 126 ? -42.948 3.433 -8.581 1.00 57.38 ? 148 VAL B N 1 ATOM 6500 C CA . VAL B 2 126 ? -44.366 3.702 -8.790 1.00 49.81 ? 148 VAL B CA 1 ATOM 6501 C C . VAL B 2 126 ? -45.010 2.600 -9.623 1.00 45.77 ? 148 VAL B C 1 ATOM 6502 O O . VAL B 2 126 ? -44.618 2.361 -10.766 1.00 48.64 ? 148 VAL B O 1 ATOM 6503 C CB . VAL B 2 126 ? -44.593 5.066 -9.471 1.00 44.70 ? 148 VAL B CB 1 ATOM 6504 C CG1 . VAL B 2 126 ? -46.067 5.299 -9.715 1.00 38.19 ? 148 VAL B CG1 1 ATOM 6505 C CG2 . VAL B 2 126 ? -44.037 6.175 -8.611 1.00 52.64 ? 148 VAL B CG2 1 ATOM 6506 N N . TRP B 2 127 ? -45.987 1.921 -9.034 1.00 42.51 ? 149 TRP B N 1 ATOM 6507 C CA . TRP B 2 127 ? -46.775 0.926 -9.747 1.00 47.03 ? 149 TRP B CA 1 ATOM 6508 C C . TRP B 2 127 ? -47.674 1.668 -10.727 1.00 47.84 ? 149 TRP B C 1 ATOM 6509 O O . TRP B 2 127 ? -47.900 2.868 -10.580 1.00 45.42 ? 149 TRP B O 1 ATOM 6510 C CB . TRP B 2 127 ? -47.619 0.110 -8.764 1.00 46.01 ? 149 TRP B CB 1 ATOM 6511 C CG . TRP B 2 127 ? -48.121 -1.192 -9.311 1.00 50.98 ? 149 TRP B CG 1 ATOM 6512 C CD1 . TRP B 2 127 ? -49.170 -1.377 -10.163 1.00 59.13 ? 149 TRP B CD1 1 ATOM 6513 C CD2 . TRP B 2 127 ? -47.604 -2.496 -9.024 1.00 48.60 ? 149 TRP B CD2 1 ATOM 6514 N NE1 . TRP B 2 127 ? -49.331 -2.715 -10.435 1.00 62.09 ? 149 TRP B NE1 1 ATOM 6515 C CE2 . TRP B 2 127 ? -48.382 -3.424 -9.745 1.00 59.93 ? 149 TRP B CE2 1 ATOM 6516 C CE3 . TRP B 2 127 ? -46.556 -2.969 -8.231 1.00 46.20 ? 149 TRP B CE3 1 ATOM 6517 C CZ2 . TRP B 2 127 ? -48.144 -4.795 -9.695 1.00 60.36 ? 149 TRP B CZ2 1 ATOM 6518 C CZ3 . TRP B 2 127 ? -46.321 -4.329 -8.183 1.00 52.14 ? 149 TRP B CZ3 1 ATOM 6519 C CH2 . TRP B 2 127 ? -47.111 -5.226 -8.910 1.00 56.24 ? 149 TRP B CH2 1 ATOM 6520 N N . GLY B 2 128 ? -48.185 0.960 -11.728 1.00 42.25 ? 150 GLY B N 1 ATOM 6521 C CA . GLY B 2 128 ? -49.074 1.563 -12.705 1.00 42.09 ? 150 GLY B CA 1 ATOM 6522 C C . GLY B 2 128 ? -50.409 1.914 -12.078 1.00 47.39 ? 150 GLY B C 1 ATOM 6523 O O . GLY B 2 128 ? -50.576 1.806 -10.865 1.00 49.22 ? 150 GLY B O 1 ATOM 6524 N N . ALA B 2 129 ? -51.372 2.318 -12.900 1.00 55.36 ? 151 ALA B N 1 ATOM 6525 C CA . ALA B 2 129 ? -52.664 2.764 -12.389 1.00 43.20 ? 151 ALA B CA 1 ATOM 6526 C C . ALA B 2 129 ? -53.564 1.584 -12.032 1.00 41.51 ? 151 ALA B C 1 ATOM 6527 O O . ALA B 2 129 ? -54.692 1.771 -11.576 1.00 42.86 ? 151 ALA B O 1 ATOM 6528 C CB . ALA B 2 129 ? -53.348 3.675 -13.392 1.00 34.87 ? 151 ALA B CB 1 ATOM 6529 N N . ASP B 2 130 ? -53.058 0.374 -12.254 1.00 43.43 ? 152 ASP B N 1 ATOM 6530 C CA . ASP B 2 130 ? -53.726 -0.840 -11.806 1.00 44.20 ? 152 ASP B CA 1 ATOM 6531 C C . ASP B 2 130 ? -53.933 -0.770 -10.301 1.00 54.44 ? 152 ASP B C 1 ATOM 6532 O O . ASP B 2 130 ? -55.055 -0.881 -9.807 1.00 70.22 ? 152 ASP B O 1 ATOM 6533 C CB . ASP B 2 130 ? -52.870 -2.064 -12.129 1.00 58.87 ? 152 ASP B CB 1 ATOM 6534 C CG . ASP B 2 130 ? -52.294 -2.025 -13.531 1.00 80.53 ? 152 ASP B CG 1 ATOM 6535 O OD1 . ASP B 2 130 ? -53.022 -1.630 -14.467 1.00 82.90 ? 152 ASP B OD1 1 ATOM 6536 O OD2 . ASP B 2 130 ? -51.108 -2.390 -13.694 1.00 83.34 ? 152 ASP B OD2 1 ATOM 6537 N N . ARG B 2 131 ? -52.831 -0.580 -9.583 1.00 50.63 ? 153 ARG B N 1 ATOM 6538 C CA . ARG B 2 131 ? -52.833 -0.499 -8.125 1.00 48.76 ? 153 ARG B CA 1 ATOM 6539 C C . ARG B 2 131 ? -52.930 0.938 -7.597 1.00 48.80 ? 153 ARG B C 1 ATOM 6540 O O . ARG B 2 131 ? -52.729 1.181 -6.406 1.00 54.35 ? 153 ARG B O 1 ATOM 6541 C CB . ARG B 2 131 ? -51.648 -1.255 -7.518 1.00 50.87 ? 153 ARG B CB 1 ATOM 6542 C CG . ARG B 2 131 ? -52.073 -2.340 -6.531 1.00 59.51 ? 153 ARG B CG 1 ATOM 6543 C CD . ARG B 2 131 ? -51.311 -3.640 -6.750 1.00 69.66 ? 153 ARG B CD 1 ATOM 6544 N NE . ARG B 2 131 ? -51.652 -4.278 -8.020 1.00 68.93 ? 153 ARG B NE 1 ATOM 6545 C CZ . ARG B 2 131 ? -52.598 -5.202 -8.163 1.00 69.86 ? 153 ARG B CZ 1 ATOM 6546 N NH1 . ARG B 2 131 ? -53.303 -5.600 -7.113 1.00 68.09 ? 153 ARG B NH1 1 ATOM 6547 N NH2 . ARG B 2 131 ? -52.838 -5.730 -9.356 1.00 66.02 ? 153 ARG B NH2 1 ATOM 6548 N N . LEU B 2 132 ? -53.206 1.875 -8.504 1.00 50.47 ? 154 LEU B N 1 ATOM 6549 C CA . LEU B 2 132 ? -53.372 3.299 -8.187 1.00 49.50 ? 154 LEU B CA 1 ATOM 6550 C C . LEU B 2 132 ? -52.093 3.985 -7.726 1.00 40.21 ? 154 LEU B C 1 ATOM 6551 O O . LEU B 2 132 ? -52.091 4.699 -6.725 1.00 49.42 ? 154 LEU B O 1 ATOM 6552 C CB . LEU B 2 132 ? -54.482 3.519 -7.148 1.00 51.88 ? 154 LEU B CB 1 ATOM 6553 C CG . LEU B 2 132 ? -55.877 2.962 -7.433 1.00 54.84 ? 154 LEU B CG 1 ATOM 6554 C CD1 . LEU B 2 132 ? -56.812 3.265 -6.267 1.00 56.46 ? 154 LEU B CD1 1 ATOM 6555 C CD2 . LEU B 2 132 ? -56.447 3.505 -8.738 1.00 51.71 ? 154 LEU B CD2 1 ATOM 6556 N N . PHE B 2 133 ? -51.011 3.753 -8.464 1.00 39.65 ? 155 PHE B N 1 ATOM 6557 C CA . PHE B 2 133 ? -49.730 4.406 -8.206 1.00 47.81 ? 155 PHE B CA 1 ATOM 6558 C C . PHE B 2 133 ? -49.209 4.041 -6.820 1.00 47.96 ? 155 PHE B C 1 ATOM 6559 O O . PHE B 2 133 ? -48.652 4.867 -6.091 1.00 42.99 ? 155 PHE B O 1 ATOM 6560 C CB . PHE B 2 133 ? -49.847 5.914 -8.423 1.00 44.55 ? 155 PHE B CB 1 ATOM 6561 C CG . PHE B 2 133 ? -50.436 6.273 -9.757 1.00 43.05 ? 155 PHE B CG 1 ATOM 6562 C CD1 . PHE B 2 133 ? -49.947 5.697 -10.920 1.00 41.95 ? 155 PHE B CD1 1 ATOM 6563 C CD2 . PHE B 2 133 ? -51.499 7.152 -9.848 1.00 45.66 ? 155 PHE B CD2 1 ATOM 6564 C CE1 . PHE B 2 133 ? -50.491 6.012 -12.151 1.00 42.69 ? 155 PHE B CE1 1 ATOM 6565 C CE2 . PHE B 2 133 ? -52.052 7.467 -11.077 1.00 48.83 ? 155 PHE B CE2 1 ATOM 6566 C CZ . PHE B 2 133 ? -51.545 6.898 -12.230 1.00 43.43 ? 155 PHE B CZ 1 ATOM 6567 N N . GLN B 2 134 ? -49.422 2.773 -6.486 1.00 48.37 ? 156 GLN B N 1 ATOM 6568 C CA . GLN B 2 134 ? -48.840 2.127 -5.324 1.00 45.11 ? 156 GLN B CA 1 ATOM 6569 C C . GLN B 2 134 ? -47.328 2.244 -5.438 1.00 44.39 ? 156 GLN B C 1 ATOM 6570 O O . GLN B 2 134 ? -46.781 2.191 -6.536 1.00 52.67 ? 156 GLN B O 1 ATOM 6571 C CB . GLN B 2 134 ? -49.267 0.658 -5.324 1.00 45.87 ? 156 GLN B CB 1 ATOM 6572 C CG . GLN B 2 134 ? -48.694 -0.205 -4.220 1.00 49.69 ? 156 GLN B CG 1 ATOM 6573 C CD . GLN B 2 134 ? -49.273 -1.612 -4.235 1.00 52.93 ? 156 GLN B CD 1 ATOM 6574 O OE1 . GLN B 2 134 ? -48.691 -2.533 -4.811 1.00 44.88 ? 156 GLN B OE1 1 ATOM 6575 N NE2 . GLN B 2 134 ? -50.430 -1.780 -3.605 1.00 60.63 ? 156 GLN B NE2 1 ATOM 6576 N N . ARG B 2 135 ? -46.649 2.414 -4.310 1.00 36.46 ? 157 ARG B N 1 ATOM 6577 C CA . ARG B 2 135 ? -45.213 2.671 -4.331 1.00 36.86 ? 157 ARG B CA 1 ATOM 6578 C C . ARG B 2 135 ? -44.393 1.387 -4.407 1.00 39.79 ? 157 ARG B C 1 ATOM 6579 O O . ARG B 2 135 ? -43.163 1.424 -4.403 1.00 45.38 ? 157 ARG B O 1 ATOM 6580 C CB . ARG B 2 135 ? -44.803 3.491 -3.110 1.00 44.96 ? 157 ARG B CB 1 ATOM 6581 C CG . ARG B 2 135 ? -44.157 4.831 -3.435 1.00 47.87 ? 157 ARG B CG 1 ATOM 6582 C CD . ARG B 2 135 ? -44.985 5.635 -4.423 1.00 46.19 ? 157 ARG B CD 1 ATOM 6583 N NE . ARG B 2 135 ? -44.642 7.054 -4.402 1.00 55.89 ? 157 ARG B NE 1 ATOM 6584 C CZ . ARG B 2 135 ? -43.583 7.584 -5.008 1.00 57.88 ? 157 ARG B CZ 1 ATOM 6585 N NH1 . ARG B 2 135 ? -42.743 6.814 -5.685 1.00 53.23 ? 157 ARG B NH1 1 ATOM 6586 N NH2 . ARG B 2 135 ? -43.362 8.889 -4.930 1.00 60.44 ? 157 ARG B NH2 1 ATOM 6587 N N . VAL B 2 136 ? -45.084 0.255 -4.475 1.00 37.52 ? 158 VAL B N 1 ATOM 6588 C CA . VAL B 2 136 ? -44.437 -1.055 -4.520 1.00 42.93 ? 158 VAL B CA 1 ATOM 6589 C C . VAL B 2 136 ? -43.588 -1.270 -5.781 1.00 47.33 ? 158 VAL B C 1 ATOM 6590 O O . VAL B 2 136 ? -44.040 -1.016 -6.898 1.00 51.40 ? 158 VAL B O 1 ATOM 6591 C CB . VAL B 2 136 ? -45.488 -2.182 -4.377 1.00 47.18 ? 158 VAL B CB 1 ATOM 6592 C CG1 . VAL B 2 136 ? -44.922 -3.523 -4.805 1.00 41.88 ? 158 VAL B CG1 1 ATOM 6593 C CG2 . VAL B 2 136 ? -45.996 -2.243 -2.941 1.00 62.04 ? 158 VAL B CG2 1 ATOM 6594 N N . CYS B 2 137 ? -42.354 -1.728 -5.586 1.00 49.24 ? 159 CYS B N 1 ATOM 6595 C CA . CYS B 2 137 ? -41.445 -2.027 -6.691 1.00 43.31 ? 159 CYS B CA 1 ATOM 6596 C C . CYS B 2 137 ? -41.739 -3.372 -7.353 1.00 45.15 ? 159 CYS B C 1 ATOM 6597 O O . CYS B 2 137 ? -41.460 -3.557 -8.538 1.00 49.08 ? 159 CYS B O 1 ATOM 6598 C CB . CYS B 2 137 ? -39.995 -1.973 -6.213 1.00 48.10 ? 159 CYS B CB 1 ATOM 6599 S SG . CYS B 2 137 ? -39.507 -0.351 -5.598 1.00 73.14 ? 159 CYS B SG 1 ATOM 6600 N N . GLN B 2 138 ? -42.299 -4.300 -6.578 1.00 45.41 ? 160 GLN B N 1 ATOM 6601 C CA . GLN B 2 138 ? -42.766 -5.594 -7.084 1.00 42.23 ? 160 GLN B CA 1 ATOM 6602 C C . GLN B 2 138 ? -43.529 -6.365 -6.010 1.00 40.49 ? 160 GLN B C 1 ATOM 6603 O O . GLN B 2 138 ? -44.583 -6.938 -6.270 1.00 30.33 ? 160 GLN B O 1 ATOM 6604 C CB . GLN B 2 138 ? -41.607 -6.445 -7.616 1.00 45.72 ? 160 GLN B CB 1 ATOM 6605 C CG . GLN B 2 138 ? -40.441 -6.609 -6.655 1.00 56.91 ? 160 GLN B CG 1 ATOM 6606 C CD . GLN B 2 138 ? -39.235 -7.245 -7.323 1.00 67.09 ? 160 GLN B CD 1 ATOM 6607 O OE1 . GLN B 2 138 ? -39.318 -7.717 -8.457 1.00 66.09 ? 160 GLN B OE1 1 ATOM 6608 N NE2 . GLN B 2 138 ? -38.106 -7.257 -6.623 1.00 66.30 ? 160 GLN B NE2 1 ATOM 6609 N N . ASP C 3 1 ? -64.060 39.842 -7.040 1.00 109.35 ? 1 ASP C N 1 ATOM 6610 C CA . ASP C 3 1 ? -63.285 40.812 -7.805 1.00 116.72 ? 1 ASP C CA 1 ATOM 6611 C C . ASP C 3 1 ? -62.040 41.259 -7.047 1.00 115.40 ? 1 ASP C C 1 ATOM 6612 O O . ASP C 3 1 ? -62.035 41.310 -5.817 1.00 106.70 ? 1 ASP C O 1 ATOM 6613 C CB . ASP C 3 1 ? -64.146 42.025 -8.164 1.00 122.06 ? 1 ASP C CB 1 ATOM 6614 C CG . ASP C 3 1 ? -65.251 41.686 -9.145 1.00 127.65 ? 1 ASP C CG 1 ATOM 6615 O OD1 . ASP C 3 1 ? -66.332 41.247 -8.698 1.00 130.92 ? 1 ASP C OD1 1 ATOM 6616 O OD2 . ASP C 3 1 ? -65.040 41.862 -10.364 1.00 121.73 ? 1 ASP C OD2 1 ATOM 6617 N N . ILE C 3 2 ? -60.986 41.578 -7.792 1.00 124.37 ? 2 ILE C N 1 ATOM 6618 C CA . ILE C 3 2 ? -59.735 42.039 -7.203 1.00 129.22 ? 2 ILE C CA 1 ATOM 6619 C C . ILE C 3 2 ? -59.477 43.494 -7.575 1.00 131.06 ? 2 ILE C C 1 ATOM 6620 O O . ILE C 3 2 ? -59.656 43.888 -8.728 1.00 130.86 ? 2 ILE C O 1 ATOM 6621 C CB . ILE C 3 2 ? -58.544 41.198 -7.692 1.00 126.41 ? 2 ILE C CB 1 ATOM 6622 C CG1 . ILE C 3 2 ? -58.904 39.713 -7.700 1.00 124.86 ? 2 ILE C CG1 1 ATOM 6623 C CG2 . ILE C 3 2 ? -57.313 41.459 -6.834 1.00 120.77 ? 2 ILE C CG2 1 ATOM 6624 C CD1 . ILE C 3 2 ? -57.786 38.830 -8.184 1.00 118.84 ? 2 ILE C CD1 1 ATOM 6625 N N . GLN C 3 3 ? -59.055 44.291 -6.599 1.00 133.52 ? 3 GLN C N 1 ATOM 6626 C CA . GLN C 3 3 ? -58.731 45.689 -6.856 1.00 135.66 ? 3 GLN C CA 1 ATOM 6627 C C . GLN C 3 3 ? -57.222 45.905 -6.902 1.00 132.73 ? 3 GLN C C 1 ATOM 6628 O O . GLN C 3 3 ? -56.494 45.489 -6.000 1.00 126.24 ? 3 GLN C O 1 ATOM 6629 C CB . GLN C 3 3 ? -59.371 46.603 -5.807 1.00 133.40 ? 3 GLN C CB 1 ATOM 6630 C CG . GLN C 3 3 ? -59.156 48.086 -6.073 1.00 134.80 ? 3 GLN C CG 1 ATOM 6631 C CD . GLN C 3 3 ? -60.014 48.969 -5.189 1.00 138.27 ? 3 GLN C CD 1 ATOM 6632 O OE1 . GLN C 3 3 ? -60.898 48.487 -4.481 1.00 136.52 ? 3 GLN C OE1 1 ATOM 6633 N NE2 . GLN C 3 3 ? -59.758 50.272 -5.227 1.00 145.66 ? 3 GLN C NE2 1 ATOM 6634 N N . MET C 3 4 ? -56.758 46.554 -7.963 1.00 133.92 ? 4 MET C N 1 ATOM 6635 C CA . MET C 3 4 ? -55.338 46.824 -8.129 1.00 134.46 ? 4 MET C CA 1 ATOM 6636 C C . MET C 3 4 ? -55.019 48.270 -7.779 1.00 137.61 ? 4 MET C C 1 ATOM 6637 O O . MET C 3 4 ? -55.642 49.198 -8.296 1.00 136.41 ? 4 MET C O 1 ATOM 6638 C CB . MET C 3 4 ? -54.897 46.523 -9.561 1.00 133.82 ? 4 MET C CB 1 ATOM 6639 C CG . MET C 3 4 ? -55.197 45.107 -10.013 1.00 135.29 ? 4 MET C CG 1 ATOM 6640 S SD . MET C 3 4 ? -54.339 43.880 -9.014 1.00 146.77 ? 4 MET C SD 1 ATOM 6641 C CE . MET C 3 4 ? -52.643 44.172 -9.512 1.00 123.98 ? 4 MET C CE 1 ATOM 6642 N N . THR C 3 5 ? -54.049 48.454 -6.891 1.00 139.85 ? 5 THR C N 1 ATOM 6643 C CA . THR C 3 5 ? -53.603 49.786 -6.511 1.00 144.15 ? 5 THR C CA 1 ATOM 6644 C C . THR C 3 5 ? -52.171 50.000 -6.988 1.00 150.46 ? 5 THR C C 1 ATOM 6645 O O . THR C 3 5 ? -51.276 49.223 -6.655 1.00 151.48 ? 5 THR C O 1 ATOM 6646 C CB . THR C 3 5 ? -53.680 49.991 -4.988 1.00 142.75 ? 5 THR C CB 1 ATOM 6647 O OG1 . THR C 3 5 ? -54.999 49.668 -4.528 1.00 137.01 ? 5 THR C OG1 1 ATOM 6648 C CG2 . THR C 3 5 ? -53.360 51.433 -4.627 1.00 145.33 ? 5 THR C CG2 1 ATOM 6649 N N . GLN C 3 6 ? -51.959 51.051 -7.773 1.00 154.74 ? 6 GLN C N 1 ATOM 6650 C CA . GLN C 3 6 ? -50.650 51.306 -8.365 1.00 160.43 ? 6 GLN C CA 1 ATOM 6651 C C . GLN C 3 6 ? -49.964 52.510 -7.725 1.00 165.12 ? 6 GLN C C 1 ATOM 6652 O O . GLN C 3 6 ? -50.582 53.556 -7.527 1.00 165.55 ? 6 GLN C O 1 ATOM 6653 C CB . GLN C 3 6 ? -50.780 51.496 -9.879 1.00 162.18 ? 6 GLN C CB 1 ATOM 6654 C CG . GLN C 3 6 ? -49.457 51.482 -10.628 1.00 169.84 ? 6 GLN C CG 1 ATOM 6655 C CD . GLN C 3 6 ? -49.633 51.249 -12.117 1.00 170.17 ? 6 GLN C CD 1 ATOM 6656 O OE1 . GLN C 3 6 ? -50.716 50.886 -12.576 1.00 168.93 ? 6 GLN C OE1 1 ATOM 6657 N NE2 . GLN C 3 6 ? -48.565 51.455 -12.879 1.00 166.95 ? 6 GLN C NE2 1 ATOM 6658 N N . SER C 3 7 ? -48.683 52.353 -7.405 1.00 170.31 ? 7 SER C N 1 ATOM 6659 C CA . SER C 3 7 ? -47.928 53.401 -6.726 1.00 176.44 ? 7 SER C CA 1 ATOM 6660 C C . SER C 3 7 ? -46.533 53.587 -7.324 1.00 180.11 ? 7 SER C C 1 ATOM 6661 O O . SER C 3 7 ? -45.877 52.612 -7.692 1.00 178.39 ? 7 SER C O 1 ATOM 6662 C CB . SER C 3 7 ? -47.815 53.083 -5.233 1.00 172.31 ? 7 SER C CB 1 ATOM 6663 O OG . SER C 3 7 ? -46.973 54.012 -4.570 1.00 169.49 ? 7 SER C OG 1 ATOM 6664 N N . PRO C 3 8 ? -46.077 54.847 -7.426 1.00 178.51 ? 8 PRO C N 1 ATOM 6665 C CA . PRO C 3 8 ? -46.875 56.041 -7.125 1.00 172.17 ? 8 PRO C CA 1 ATOM 6666 C C . PRO C 3 8 ? -47.825 56.364 -8.276 1.00 175.94 ? 8 PRO C C 1 ATOM 6667 O O . PRO C 3 8 ? -47.810 55.667 -9.290 1.00 174.74 ? 8 PRO C O 1 ATOM 6668 C CB . PRO C 3 8 ? -45.820 57.147 -6.988 1.00 165.11 ? 8 PRO C CB 1 ATOM 6669 C CG . PRO C 3 8 ? -44.503 56.433 -6.850 1.00 169.93 ? 8 PRO C CG 1 ATOM 6670 C CD . PRO C 3 8 ? -44.662 55.182 -7.646 1.00 175.56 ? 8 PRO C CD 1 ATOM 6671 N N . SER C 3 9 ? -48.636 57.405 -8.119 1.00 180.03 ? 9 SER C N 1 ATOM 6672 C CA . SER C 3 9 ? -49.619 57.760 -9.137 1.00 177.02 ? 9 SER C CA 1 ATOM 6673 C C . SER C 3 9 ? -48.961 58.428 -10.340 1.00 182.02 ? 9 SER C C 1 ATOM 6674 O O . SER C 3 9 ? -49.392 58.241 -11.477 1.00 183.05 ? 9 SER C O 1 ATOM 6675 C CB . SER C 3 9 ? -50.700 58.669 -8.549 1.00 166.38 ? 9 SER C CB 1 ATOM 6676 O OG . SER C 3 9 ? -51.746 58.883 -9.481 1.00 167.57 ? 9 SER C OG 1 ATOM 6677 N N . SER C 3 10 ? -47.916 59.209 -10.082 1.00 184.79 ? 10 SER C N 1 ATOM 6678 C CA . SER C 3 10 ? -47.183 59.885 -11.146 1.00 182.41 ? 10 SER C CA 1 ATOM 6679 C C . SER C 3 10 ? -45.696 59.983 -10.818 1.00 181.28 ? 10 SER C C 1 ATOM 6680 O O . SER C 3 10 ? -45.321 60.227 -9.671 1.00 181.48 ? 10 SER C O 1 ATOM 6681 C CB . SER C 3 10 ? -47.757 61.283 -11.386 1.00 183.21 ? 10 SER C CB 1 ATOM 6682 O OG . SER C 3 10 ? -47.701 62.067 -10.206 1.00 189.18 ? 10 SER C OG 1 ATOM 6683 N N . VAL C 3 11 ? -44.852 59.789 -11.828 1.00 181.58 ? 11 VAL C N 1 ATOM 6684 C CA . VAL C 3 11 ? -43.405 59.888 -11.649 1.00 183.74 ? 11 VAL C CA 1 ATOM 6685 C C . VAL C 3 11 ? -42.755 60.710 -12.759 1.00 181.57 ? 11 VAL C C 1 ATOM 6686 O O . VAL C 3 11 ? -42.882 60.385 -13.940 1.00 179.32 ? 11 VAL C O 1 ATOM 6687 C CB . VAL C 3 11 ? -42.732 58.498 -11.600 1.00 180.97 ? 11 VAL C CB 1 ATOM 6688 C CG1 . VAL C 3 11 ? -41.223 58.646 -11.488 1.00 173.68 ? 11 VAL C CG1 1 ATOM 6689 C CG2 . VAL C 3 11 ? -43.272 57.674 -10.441 1.00 181.21 ? 11 VAL C CG2 1 ATOM 6690 N N . SER C 3 12 ? -42.057 61.774 -12.372 1.00 178.70 ? 12 SER C N 1 ATOM 6691 C CA . SER C 3 12 ? -41.327 62.601 -13.326 1.00 169.80 ? 12 SER C CA 1 ATOM 6692 C C . SER C 3 12 ? -39.841 62.613 -12.993 1.00 170.34 ? 12 SER C C 1 ATOM 6693 O O . SER C 3 12 ? -39.435 63.136 -11.956 1.00 168.85 ? 12 SER C O 1 ATOM 6694 C CB . SER C 3 12 ? -41.872 64.031 -13.328 1.00 165.16 ? 12 SER C CB 1 ATOM 6695 O OG . SER C 3 12 ? -41.557 64.699 -12.119 1.00 162.66 ? 12 SER C OG 1 ATOM 6696 N N . ALA C 3 13 ? -39.031 62.036 -13.875 1.00 173.97 ? 13 ALA C N 1 ATOM 6697 C CA . ALA C 3 13 ? -37.589 61.988 -13.667 1.00 171.37 ? 13 ALA C CA 1 ATOM 6698 C C . ALA C 3 13 ? -36.839 62.458 -14.907 1.00 172.20 ? 13 ALA C C 1 ATOM 6699 O O . ALA C 3 13 ? -37.448 62.785 -15.926 1.00 170.27 ? 13 ALA C O 1 ATOM 6700 C CB . ALA C 3 13 ? -37.155 60.581 -13.286 1.00 167.46 ? 13 ALA C CB 1 ATOM 6701 N N . SER C 3 14 ? -35.513 62.487 -14.817 1.00 174.02 ? 14 SER C N 1 ATOM 6702 C CA . SER C 3 14 ? -34.684 62.892 -15.944 1.00 173.55 ? 14 SER C CA 1 ATOM 6703 C C . SER C 3 14 ? -34.392 61.690 -16.835 1.00 169.62 ? 14 SER C C 1 ATOM 6704 O O . SER C 3 14 ? -34.803 60.571 -16.531 1.00 171.64 ? 14 SER C O 1 ATOM 6705 C CB . SER C 3 14 ? -33.375 63.514 -15.452 1.00 171.88 ? 14 SER C CB 1 ATOM 6706 O OG . SER C 3 14 ? -33.622 64.576 -14.546 1.00 174.34 ? 14 SER C OG 1 ATOM 6707 N N . VAL C 3 15 ? -33.676 61.923 -17.929 1.00 164.83 ? 15 VAL C N 1 ATOM 6708 C CA . VAL C 3 15 ? -33.328 60.851 -18.854 1.00 163.48 ? 15 VAL C CA 1 ATOM 6709 C C . VAL C 3 15 ? -32.178 60.010 -18.307 1.00 163.82 ? 15 VAL C C 1 ATOM 6710 O O . VAL C 3 15 ? -31.107 60.535 -18.002 1.00 167.85 ? 15 VAL C O 1 ATOM 6711 C CB . VAL C 3 15 ? -32.938 61.409 -20.238 1.00 158.72 ? 15 VAL C CB 1 ATOM 6712 C CG1 . VAL C 3 15 ? -32.498 60.286 -21.165 1.00 158.95 ? 15 VAL C CG1 1 ATOM 6713 C CG2 . VAL C 3 15 ? -34.098 62.185 -20.842 1.00 154.58 ? 15 VAL C CG2 1 ATOM 6714 N N . GLY C 3 16 ? -32.404 58.706 -18.180 1.00 163.53 ? 16 GLY C N 1 ATOM 6715 C CA . GLY C 3 16 ? -31.367 57.798 -17.725 1.00 168.03 ? 16 GLY C CA 1 ATOM 6716 C C . GLY C 3 16 ? -31.507 57.356 -16.280 1.00 165.74 ? 16 GLY C C 1 ATOM 6717 O O . GLY C 3 16 ? -30.854 56.404 -15.852 1.00 161.32 ? 16 GLY C O 1 ATOM 6718 N N . ASP C 3 17 ? -32.352 58.048 -15.522 1.00 169.01 ? 17 ASP C N 1 ATOM 6719 C CA . ASP C 3 17 ? -32.576 57.700 -14.122 1.00 172.86 ? 17 ASP C CA 1 ATOM 6720 C C . ASP C 3 17 ? -33.390 56.416 -14.007 1.00 173.68 ? 17 ASP C C 1 ATOM 6721 O O . ASP C 3 17 ? -34.111 56.047 -14.934 1.00 171.87 ? 17 ASP C O 1 ATOM 6722 C CB . ASP C 3 17 ? -33.299 58.834 -13.393 1.00 172.16 ? 17 ASP C CB 1 ATOM 6723 C CG . ASP C 3 17 ? -32.532 60.141 -13.438 1.00 168.23 ? 17 ASP C CG 1 ATOM 6724 O OD1 . ASP C 3 17 ? -31.312 60.110 -13.701 1.00 163.91 ? 17 ASP C OD1 1 ATOM 6725 O OD2 . ASP C 3 17 ? -33.152 61.199 -13.203 1.00 164.86 ? 17 ASP C OD2 1 ATOM 6726 N N . ARG C 3 18 ? -33.277 55.738 -12.869 1.00 173.58 ? 18 ARG C N 1 ATOM 6727 C CA . ARG C 3 18 ? -34.058 54.527 -12.637 1.00 171.60 ? 18 ARG C CA 1 ATOM 6728 C C . ARG C 3 18 ? -35.442 54.853 -12.086 1.00 172.39 ? 18 ARG C C 1 ATOM 6729 O O . ARG C 3 18 ? -35.576 55.448 -11.016 1.00 165.21 ? 18 ARG C O 1 ATOM 6730 C CB . ARG C 3 18 ? -33.327 53.564 -11.697 1.00 160.46 ? 18 ARG C CB 1 ATOM 6731 C CG . ARG C 3 18 ? -32.154 52.836 -12.335 1.00 153.05 ? 18 ARG C CG 1 ATOM 6732 C CD . ARG C 3 18 ? -31.769 51.607 -11.528 1.00 145.31 ? 18 ARG C CD 1 ATOM 6733 N NE . ARG C 3 18 ? -31.572 51.923 -10.116 1.00 142.18 ? 18 ARG C NE 1 ATOM 6734 C CZ . ARG C 3 18 ? -30.411 52.293 -9.589 1.00 147.73 ? 18 ARG C CZ 1 ATOM 6735 N NH1 . ARG C 3 18 ? -29.335 52.394 -10.358 1.00 153.11 ? 18 ARG C NH1 1 ATOM 6736 N NH2 . ARG C 3 18 ? -30.323 52.563 -8.294 1.00 149.45 ? 18 ARG C NH2 1 ATOM 6737 N N . VAL C 3 19 ? -36.470 54.456 -12.829 1.00 173.56 ? 19 VAL C N 1 ATOM 6738 C CA . VAL C 3 19 ? -37.849 54.695 -12.428 1.00 167.94 ? 19 VAL C CA 1 ATOM 6739 C C . VAL C 3 19 ? -38.483 53.402 -11.921 1.00 165.07 ? 19 VAL C C 1 ATOM 6740 O O . VAL C 3 19 ? -38.377 52.358 -12.564 1.00 164.35 ? 19 VAL C O 1 ATOM 6741 C CB . VAL C 3 19 ? -38.678 55.260 -13.598 1.00 167.16 ? 19 VAL C CB 1 ATOM 6742 C CG1 . VAL C 3 19 ? -40.095 55.571 -13.147 1.00 174.57 ? 19 VAL C CG1 1 ATOM 6743 C CG2 . VAL C 3 19 ? -38.011 56.504 -14.166 1.00 160.54 ? 19 VAL C CG2 1 ATOM 6744 N N . THR C 3 20 ? -39.134 53.474 -10.765 1.00 164.28 ? 20 THR C N 1 ATOM 6745 C CA . THR C 3 20 ? -39.751 52.295 -10.166 1.00 164.91 ? 20 THR C CA 1 ATOM 6746 C C . THR C 3 20 ? -41.238 52.500 -9.881 1.00 170.19 ? 20 THR C C 1 ATOM 6747 O O . THR C 3 20 ? -41.616 53.341 -9.066 1.00 171.70 ? 20 THR C O 1 ATOM 6748 C CB . THR C 3 20 ? -39.032 51.884 -8.865 1.00 160.99 ? 20 THR C CB 1 ATOM 6749 O OG1 . THR C 3 20 ? -37.677 51.524 -9.161 1.00 162.00 ? 20 THR C OG1 1 ATOM 6750 C CG2 . THR C 3 20 ? -39.733 50.703 -8.215 1.00 159.90 ? 20 THR C CG2 1 ATOM 6751 N N . ILE C 3 21 ? -42.077 51.724 -10.562 1.00 169.80 ? 21 ILE C N 1 ATOM 6752 C CA . ILE C 3 21 ? -43.516 51.758 -10.337 1.00 164.67 ? 21 ILE C CA 1 ATOM 6753 C C . ILE C 3 21 ? -43.994 50.376 -9.912 1.00 162.07 ? 21 ILE C C 1 ATOM 6754 O O . ILE C 3 21 ? -43.875 49.415 -10.672 1.00 160.97 ? 21 ILE C O 1 ATOM 6755 C CB . ILE C 3 21 ? -44.283 52.163 -11.613 1.00 162.30 ? 21 ILE C CB 1 ATOM 6756 C CG1 . ILE C 3 21 ? -43.612 53.355 -12.299 1.00 159.94 ? 21 ILE C CG1 1 ATOM 6757 C CG2 . ILE C 3 21 ? -45.737 52.470 -11.286 1.00 164.68 ? 21 ILE C CG2 1 ATOM 6758 C CD1 . ILE C 3 21 ? -44.226 53.709 -13.638 1.00 155.97 ? 21 ILE C CD1 1 ATOM 6759 N N . THR C 3 22 ? -44.534 50.268 -8.702 1.00 163.19 ? 22 THR C N 1 ATOM 6760 C CA . THR C 3 22 ? -45.059 48.989 -8.242 1.00 167.47 ? 22 THR C CA 1 ATOM 6761 C C . THR C 3 22 ? -46.561 48.915 -8.480 1.00 166.15 ? 22 THR C C 1 ATOM 6762 O O . THR C 3 22 ? -47.181 49.888 -8.908 1.00 163.34 ? 22 THR C O 1 ATOM 6763 C CB . THR C 3 22 ? -44.775 48.762 -6.740 1.00 163.44 ? 22 THR C CB 1 ATOM 6764 O OG1 . THR C 3 22 ? -45.337 47.509 -6.326 1.00 158.21 ? 22 THR C OG1 1 ATOM 6765 C CG2 . THR C 3 22 ? -45.381 49.881 -5.907 1.00 161.94 ? 22 THR C CG2 1 ATOM 6766 N N . CYS C 3 23 ? -47.139 47.753 -8.202 1.00 158.88 ? 23 CYS C N 1 ATOM 6767 C CA . CYS C 3 23 ? -48.577 47.568 -8.309 1.00 148.73 ? 23 CYS C CA 1 ATOM 6768 C C . CYS C 3 23 ? -49.038 46.665 -7.176 1.00 148.34 ? 23 CYS C C 1 ATOM 6769 O O . CYS C 3 23 ? -48.485 45.584 -6.980 1.00 151.59 ? 23 CYS C O 1 ATOM 6770 C CB . CYS C 3 23 ? -48.937 46.955 -9.663 1.00 148.26 ? 23 CYS C CB 1 ATOM 6771 S SG . CYS C 3 23 ? -50.685 47.071 -10.094 1.00 170.24 ? 23 CYS C SG 1 ATOM 6772 N N . ARG C 3 24 ? -50.046 47.101 -6.429 1.00 147.97 ? 24 ARG C N 1 ATOM 6773 C CA . ARG C 3 24 ? -50.538 46.301 -5.315 1.00 143.03 ? 24 ARG C CA 1 ATOM 6774 C C . ARG C 3 24 ? -51.807 45.555 -5.695 1.00 139.69 ? 24 ARG C C 1 ATOM 6775 O O . ARG C 3 24 ? -52.353 45.750 -6.779 1.00 143.59 ? 24 ARG C O 1 ATOM 6776 C CB . ARG C 3 24 ? -50.796 47.187 -4.096 1.00 141.27 ? 24 ARG C CB 1 ATOM 6777 C CG . ARG C 3 24 ? -49.552 47.877 -3.568 1.00 148.59 ? 24 ARG C CG 1 ATOM 6778 C CD . ARG C 3 24 ? -49.870 48.765 -2.378 1.00 153.65 ? 24 ARG C CD 1 ATOM 6779 N NE . ARG C 3 24 ? -48.658 49.292 -1.757 1.00 166.52 ? 24 ARG C NE 1 ATOM 6780 C CZ . ARG C 3 24 ? -48.650 50.113 -0.712 1.00 168.41 ? 24 ARG C CZ 1 ATOM 6781 N NH1 . ARG C 3 24 ? -47.499 50.541 -0.211 1.00 164.71 ? 24 ARG C NH1 1 ATOM 6782 N NH2 . ARG C 3 24 ? -49.793 50.507 -0.167 1.00 167.85 ? 24 ARG C NH2 1 ATOM 6783 N N . ALA C 3 25 ? -52.285 44.714 -4.785 1.00 130.34 ? 25 ALA C N 1 ATOM 6784 C CA . ALA C 3 25 ? -53.471 43.910 -5.040 1.00 128.03 ? 25 ALA C CA 1 ATOM 6785 C C . ALA C 3 25 ? -54.188 43.582 -3.741 1.00 130.15 ? 25 ALA C C 1 ATOM 6786 O O . ALA C 3 25 ? -53.558 43.451 -2.692 1.00 125.74 ? 25 ALA C O 1 ATOM 6787 C CB . ALA C 3 25 ? -53.094 42.634 -5.771 1.00 128.75 ? 25 ALA C CB 1 ATOM 6788 N N . SER C 3 26 ? -55.507 43.449 -3.817 1.00 129.86 ? 26 SER C N 1 ATOM 6789 C CA . SER C 3 26 ? -56.300 43.062 -2.659 1.00 123.86 ? 26 SER C CA 1 ATOM 6790 C C . SER C 3 26 ? -55.966 41.627 -2.271 1.00 124.90 ? 26 SER C C 1 ATOM 6791 O O . SER C 3 26 ? -55.678 41.332 -1.111 1.00 125.10 ? 26 SER C O 1 ATOM 6792 C CB . SER C 3 26 ? -57.791 43.186 -2.973 1.00 117.12 ? 26 SER C CB 1 ATOM 6793 O OG . SER C 3 26 ? -58.100 44.475 -3.473 1.00 119.04 ? 26 SER C OG 1 ATOM 6794 N N . GLN C 3 27 ? -56.006 40.741 -3.260 1.00 128.19 ? 27 GLN C N 1 ATOM 6795 C CA . GLN C 3 27 ? -55.708 39.327 -3.058 1.00 126.33 ? 27 GLN C CA 1 ATOM 6796 C C . GLN C 3 27 ? -54.214 39.045 -2.883 1.00 120.71 ? 27 GLN C C 1 ATOM 6797 O O . GLN C 3 27 ? -53.365 39.868 -3.225 1.00 119.10 ? 27 GLN C O 1 ATOM 6798 C CB . GLN C 3 27 ? -56.290 38.482 -4.195 1.00 126.36 ? 27 GLN C CB 1 ATOM 6799 C CG . GLN C 3 27 ? -57.778 38.704 -4.450 1.00 120.73 ? 27 GLN C CG 1 ATOM 6800 C CD . GLN C 3 27 ? -58.679 38.160 -3.350 1.00 116.17 ? 27 GLN C CD 1 ATOM 6801 O OE1 . GLN C 3 27 ? -58.211 37.620 -2.347 1.00 109.94 ? 27 GLN C OE1 1 ATOM 6802 N NE2 . GLN C 3 27 ? -59.986 38.299 -3.542 1.00 115.48 ? 27 GLN C NE2 1 ATOM 6803 N N . GLY C 3 28 ? -53.915 37.865 -2.349 1.00 117.37 ? 28 GLY C N 1 ATOM 6804 C CA . GLY C 3 28 ? -52.558 37.441 -2.050 1.00 124.76 ? 28 GLY C CA 1 ATOM 6805 C C . GLY C 3 28 ? -51.880 36.765 -3.228 1.00 135.19 ? 28 GLY C C 1 ATOM 6806 O O . GLY C 3 28 ? -50.995 35.928 -3.048 1.00 139.19 ? 28 GLY C O 1 ATOM 6807 N N . ILE C 3 29 ? -52.311 37.136 -4.432 1.00 134.52 ? 29 ILE C N 1 ATOM 6808 C CA . ILE C 3 29 ? -51.977 36.438 -5.675 1.00 130.77 ? 29 ILE C CA 1 ATOM 6809 C C . ILE C 3 29 ? -50.492 36.106 -5.883 1.00 128.23 ? 29 ILE C C 1 ATOM 6810 O O . ILE C 3 29 ? -49.605 36.907 -5.584 1.00 127.31 ? 29 ILE C O 1 ATOM 6811 C CB . ILE C 3 29 ? -52.481 37.238 -6.890 1.00 124.15 ? 29 ILE C CB 1 ATOM 6812 C CG1 . ILE C 3 29 ? -51.827 38.619 -6.934 1.00 127.33 ? 29 ILE C CG1 1 ATOM 6813 C CG2 . ILE C 3 29 ? -53.994 37.372 -6.849 1.00 118.83 ? 29 ILE C CG2 1 ATOM 6814 C CD1 . ILE C 3 29 ? -52.148 39.398 -8.180 1.00 117.44 ? 29 ILE C CD1 1 ATOM 6815 N N . SER C 3 30 ? -50.250 34.894 -6.377 1.00 124.60 ? 30 SER C N 1 ATOM 6816 C CA . SER C 3 30 ? -48.907 34.324 -6.482 1.00 120.07 ? 30 SER C CA 1 ATOM 6817 C C . SER C 3 30 ? -47.883 35.073 -7.343 1.00 123.66 ? 30 SER C C 1 ATOM 6818 O O . SER C 3 30 ? -46.945 35.666 -6.813 1.00 138.57 ? 30 SER C O 1 ATOM 6819 C CB . SER C 3 30 ? -48.992 32.859 -6.918 1.00 111.51 ? 30 SER C CB 1 ATOM 6820 N N . SER C 3 31 ? -48.058 35.045 -8.663 1.00 110.55 ? 31 SER C N 1 ATOM 6821 C CA . SER C 3 31 ? -46.951 35.388 -9.558 1.00 117.10 ? 31 SER C CA 1 ATOM 6822 C C . SER C 3 31 ? -47.206 36.417 -10.665 1.00 121.50 ? 31 SER C C 1 ATOM 6823 O O . SER C 3 31 ? -46.681 37.528 -10.618 1.00 130.57 ? 31 SER C O 1 ATOM 6824 C CB . SER C 3 31 ? -46.356 34.115 -10.158 1.00 115.76 ? 31 SER C CB 1 ATOM 6825 N N . TRP C 3 32 ? -48.006 36.042 -11.658 1.00 122.16 ? 32 TRP C N 1 ATOM 6826 C CA . TRP C 3 32 ? -48.030 36.756 -12.939 1.00 117.28 ? 32 TRP C CA 1 ATOM 6827 C C . TRP C 3 32 ? -48.723 38.116 -12.921 1.00 114.95 ? 32 TRP C C 1 ATOM 6828 O O . TRP C 3 32 ? -49.900 38.231 -12.575 1.00 109.72 ? 32 TRP C O 1 ATOM 6829 C CB . TRP C 3 32 ? -48.658 35.870 -14.021 1.00 109.49 ? 32 TRP C CB 1 ATOM 6830 C CG . TRP C 3 32 ? -49.299 34.661 -13.443 1.00 111.42 ? 32 TRP C CG 1 ATOM 6831 C CD1 . TRP C 3 32 ? -50.588 34.544 -13.012 1.00 114.07 ? 32 TRP C CD1 1 ATOM 6832 C CD2 . TRP C 3 32 ? -48.680 33.396 -13.204 1.00 110.00 ? 32 TRP C CD2 1 ATOM 6833 N NE1 . TRP C 3 32 ? -50.810 33.285 -12.522 1.00 115.87 ? 32 TRP C NE1 1 ATOM 6834 C CE2 . TRP C 3 32 ? -49.652 32.555 -12.631 1.00 110.98 ? 32 TRP C CE2 1 ATOM 6835 C CE3 . TRP C 3 32 ? -47.395 32.887 -13.422 1.00 107.42 ? 32 TRP C CE3 1 ATOM 6836 C CZ2 . TRP C 3 32 ? -49.382 31.236 -12.270 1.00 108.36 ? 32 TRP C CZ2 1 ATOM 6837 C CZ3 . TRP C 3 32 ? -47.130 31.581 -13.067 1.00 107.74 ? 32 TRP C CZ3 1 ATOM 6838 C CH2 . TRP C 3 32 ? -48.117 30.768 -12.499 1.00 112.08 ? 32 TRP C CH2 1 ATOM 6839 N N . LEU C 3 33 ? -47.970 39.140 -13.309 1.00 117.12 ? 33 LEU C N 1 ATOM 6840 C CA . LEU C 3 33 ? -48.519 40.465 -13.563 1.00 115.96 ? 33 LEU C CA 1 ATOM 6841 C C . LEU C 3 33 ? -48.138 40.882 -14.978 1.00 118.37 ? 33 LEU C C 1 ATOM 6842 O O . LEU C 3 33 ? -47.052 40.554 -15.454 1.00 123.24 ? 33 LEU C O 1 ATOM 6843 C CB . LEU C 3 33 ? -48.002 41.486 -12.545 1.00 121.19 ? 33 LEU C CB 1 ATOM 6844 C CG . LEU C 3 33 ? -48.983 41.892 -11.440 1.00 134.91 ? 33 LEU C CG 1 ATOM 6845 C CD1 . LEU C 3 33 ? -49.265 40.726 -10.504 1.00 138.79 ? 33 LEU C CD1 1 ATOM 6846 C CD2 . LEU C 3 33 ? -48.472 43.096 -10.660 1.00 143.35 ? 33 LEU C CD2 1 ATOM 6847 N N . ALA C 3 34 ? -49.032 41.596 -15.653 1.00 121.31 ? 34 ALA C N 1 ATOM 6848 C CA . ALA C 3 34 ? -48.793 41.991 -17.037 1.00 117.59 ? 34 ALA C CA 1 ATOM 6849 C C . ALA C 3 34 ? -48.696 43.504 -17.194 1.00 125.81 ? 34 ALA C C 1 ATOM 6850 O O . ALA C 3 34 ? -49.674 44.222 -16.989 1.00 127.66 ? 34 ALA C O 1 ATOM 6851 C CB . ALA C 3 34 ? -49.879 41.432 -17.943 1.00 108.87 ? 34 ALA C CB 1 ATOM 6852 N N . TRP C 3 35 ? -47.512 43.980 -17.566 1.00 130.18 ? 35 TRP C N 1 ATOM 6853 C CA . TRP C 3 35 ? -47.293 45.407 -17.771 1.00 130.86 ? 35 TRP C CA 1 ATOM 6854 C C . TRP C 3 35 ? -47.598 45.828 -19.205 1.00 133.33 ? 35 TRP C C 1 ATOM 6855 O O . TRP C 3 35 ? -47.264 45.124 -20.158 1.00 131.72 ? 35 TRP C O 1 ATOM 6856 C CB . TRP C 3 35 ? -45.858 45.793 -17.404 1.00 126.68 ? 35 TRP C CB 1 ATOM 6857 C CG . TRP C 3 35 ? -45.561 45.680 -15.941 1.00 123.74 ? 35 TRP C CG 1 ATOM 6858 C CD1 . TRP C 3 35 ? -44.865 44.685 -15.319 1.00 126.28 ? 35 TRP C CD1 1 ATOM 6859 C CD2 . TRP C 3 35 ? -45.957 46.596 -14.914 1.00 136.49 ? 35 TRP C CD2 1 ATOM 6860 N NE1 . TRP C 3 35 ? -44.800 44.926 -13.967 1.00 137.13 ? 35 TRP C NE1 1 ATOM 6861 C CE2 . TRP C 3 35 ? -45.464 46.093 -13.693 1.00 146.22 ? 35 TRP C CE2 1 ATOM 6862 C CE3 . TRP C 3 35 ? -46.680 47.792 -14.907 1.00 141.72 ? 35 TRP C CE3 1 ATOM 6863 C CZ2 . TRP C 3 35 ? -45.672 46.745 -12.479 1.00 153.94 ? 35 TRP C CZ2 1 ATOM 6864 C CZ3 . TRP C 3 35 ? -46.884 48.439 -13.702 1.00 150.78 ? 35 TRP C CZ3 1 ATOM 6865 C CH2 . TRP C 3 35 ? -46.383 47.914 -12.504 1.00 158.16 ? 35 TRP C CH2 1 ATOM 6866 N N . TYR C 3 36 ? -48.238 46.984 -19.346 1.00 134.07 ? 36 TYR C N 1 ATOM 6867 C CA . TYR C 3 36 ? -48.551 47.537 -20.656 1.00 139.17 ? 36 TYR C CA 1 ATOM 6868 C C . TYR C 3 36 ? -48.065 48.981 -20.726 1.00 149.22 ? 36 TYR C C 1 ATOM 6869 O O . TYR C 3 36 ? -47.801 49.603 -19.698 1.00 152.75 ? 36 TYR C O 1 ATOM 6870 C CB . TYR C 3 36 ? -50.060 47.481 -20.919 1.00 140.15 ? 36 TYR C CB 1 ATOM 6871 C CG . TYR C 3 36 ? -50.648 46.085 -20.920 1.00 135.32 ? 36 TYR C CG 1 ATOM 6872 C CD1 . TYR C 3 36 ? -50.938 45.433 -22.112 1.00 130.14 ? 36 TYR C CD1 1 ATOM 6873 C CD2 . TYR C 3 36 ? -50.921 45.423 -19.729 1.00 130.64 ? 36 TYR C CD2 1 ATOM 6874 C CE1 . TYR C 3 36 ? -51.478 44.159 -22.116 1.00 125.15 ? 36 TYR C CE1 1 ATOM 6875 C CE2 . TYR C 3 36 ? -51.460 44.151 -19.725 1.00 127.80 ? 36 TYR C CE2 1 ATOM 6876 C CZ . TYR C 3 36 ? -51.737 43.524 -20.920 1.00 127.86 ? 36 TYR C CZ 1 ATOM 6877 O OH . TYR C 3 36 ? -52.274 42.257 -20.916 1.00 126.81 ? 36 TYR C OH 1 ATOM 6878 N N . GLN C 3 37 ? -47.939 49.508 -21.939 1.00 152.77 ? 37 GLN C N 1 ATOM 6879 C CA . GLN C 3 37 ? -47.573 50.908 -22.123 1.00 152.02 ? 37 GLN C CA 1 ATOM 6880 C C . GLN C 3 37 ? -48.492 51.581 -23.133 1.00 159.06 ? 37 GLN C C 1 ATOM 6881 O O . GLN C 3 37 ? -48.516 51.206 -24.305 1.00 157.10 ? 37 GLN C O 1 ATOM 6882 C CB . GLN C 3 37 ? -46.124 51.029 -22.565 1.00 146.46 ? 37 GLN C CB 1 ATOM 6883 N N . GLN C 3 38 ? -49.247 52.575 -22.677 1.00 168.38 ? 38 GLN C N 1 ATOM 6884 C CA . GLN C 3 38 ? -50.106 53.337 -23.574 1.00 168.19 ? 38 GLN C CA 1 ATOM 6885 C C . GLN C 3 38 ? -49.605 54.763 -23.735 1.00 172.35 ? 38 GLN C C 1 ATOM 6886 O O . GLN C 3 38 ? -49.681 55.568 -22.807 1.00 174.04 ? 38 GLN C O 1 ATOM 6887 C CB . GLN C 3 38 ? -51.551 53.364 -23.075 1.00 167.20 ? 38 GLN C CB 1 ATOM 6888 C CG . GLN C 3 38 ? -52.474 54.198 -23.958 1.00 167.22 ? 38 GLN C CG 1 ATOM 6889 C CD . GLN C 3 38 ? -53.820 54.481 -23.319 1.00 172.36 ? 38 GLN C CD 1 ATOM 6890 O OE1 . GLN C 3 38 ? -54.744 54.957 -23.978 1.00 167.81 ? 38 GLN C OE1 1 ATOM 6891 N NE2 . GLN C 3 38 ? -53.935 54.195 -22.028 1.00 174.82 ? 38 GLN C NE2 1 ATOM 6892 N N . LYS C 3 39 ? -49.094 55.071 -24.921 1.00 173.44 ? 39 LYS C N 1 ATOM 6893 C CA . LYS C 3 39 ? -48.741 56.438 -25.261 1.00 174.98 ? 39 LYS C CA 1 ATOM 6894 C C . LYS C 3 39 ? -50.033 57.147 -25.638 1.00 168.81 ? 39 LYS C C 1 ATOM 6895 O O . LYS C 3 39 ? -50.921 56.532 -26.227 1.00 165.62 ? 39 LYS C O 1 ATOM 6896 C CB . LYS C 3 39 ? -47.737 56.458 -26.414 1.00 179.47 ? 39 LYS C CB 1 ATOM 6897 C CG . LYS C 3 39 ? -46.454 55.696 -26.102 1.00 177.14 ? 39 LYS C CG 1 ATOM 6898 C CD . LYS C 3 39 ? -45.510 55.633 -27.292 1.00 165.47 ? 39 LYS C CD 1 ATOM 6899 C CE . LYS C 3 39 ? -44.270 54.816 -26.955 1.00 147.01 ? 39 LYS C CE 1 ATOM 6900 N NZ . LYS C 3 39 ? -43.335 54.704 -28.107 1.00 140.00 ? 39 LYS C NZ 1 ATOM 6901 N N . PRO C 3 40 ? -50.158 58.433 -25.272 1.00 170.80 ? 40 PRO C N 1 ATOM 6902 C CA . PRO C 3 40 ? -51.416 59.160 -25.484 1.00 174.50 ? 40 PRO C CA 1 ATOM 6903 C C . PRO C 3 40 ? -51.880 59.138 -26.940 1.00 172.49 ? 40 PRO C C 1 ATOM 6904 O O . PRO C 3 40 ? -51.129 59.505 -27.845 1.00 169.18 ? 40 PRO C O 1 ATOM 6905 C CB . PRO C 3 40 ? -51.061 60.588 -25.065 1.00 175.11 ? 40 PRO C CB 1 ATOM 6906 C CG . PRO C 3 40 ? -49.969 60.416 -24.064 1.00 172.22 ? 40 PRO C CG 1 ATOM 6907 C CD . PRO C 3 40 ? -49.164 59.245 -24.549 1.00 170.56 ? 40 PRO C CD 1 ATOM 6908 N N . GLY C 3 41 ? -53.121 58.708 -27.145 1.00 172.51 ? 41 GLY C N 1 ATOM 6909 C CA . GLY C 3 41 ? -53.708 58.608 -28.469 1.00 164.96 ? 41 GLY C CA 1 ATOM 6910 C C . GLY C 3 41 ? -53.391 57.276 -29.123 1.00 162.71 ? 41 GLY C C 1 ATOM 6911 O O . GLY C 3 41 ? -54.121 56.806 -29.995 1.00 154.83 ? 41 GLY C O 1 ATOM 6912 N N . LYS C 3 42 ? -52.291 56.667 -28.689 1.00 170.10 ? 42 LYS C N 1 ATOM 6913 C CA . LYS C 3 42 ? -51.853 55.370 -29.194 1.00 169.79 ? 42 LYS C CA 1 ATOM 6914 C C . LYS C 3 42 ? -52.551 54.195 -28.512 1.00 173.63 ? 42 LYS C C 1 ATOM 6915 O O . LYS C 3 42 ? -53.030 54.313 -27.384 1.00 179.02 ? 42 LYS C O 1 ATOM 6916 C CB . LYS C 3 42 ? -50.341 55.235 -29.074 1.00 162.89 ? 42 LYS C CB 1 ATOM 6917 N N . ALA C 3 43 ? -52.607 53.064 -29.210 1.00 168.76 ? 43 ALA C N 1 ATOM 6918 C CA . ALA C 3 43 ? -53.089 51.818 -28.626 1.00 163.57 ? 43 ALA C CA 1 ATOM 6919 C C . ALA C 3 43 ? -52.046 51.272 -27.653 1.00 169.91 ? 43 ALA C C 1 ATOM 6920 O O . ALA C 3 43 ? -50.851 51.506 -27.832 1.00 170.40 ? 43 ALA C O 1 ATOM 6921 C CB . ALA C 3 43 ? -53.374 50.803 -29.722 1.00 154.83 ? 43 ALA C CB 1 ATOM 6922 N N . PRO C 3 44 ? -52.494 50.549 -26.613 1.00 170.57 ? 44 PRO C N 1 ATOM 6923 C CA . PRO C 3 44 ? -51.573 49.963 -25.629 1.00 163.02 ? 44 PRO C CA 1 ATOM 6924 C C . PRO C 3 44 ? -50.619 48.941 -26.247 1.00 158.47 ? 44 PRO C C 1 ATOM 6925 O O . PRO C 3 44 ? -50.890 48.424 -27.331 1.00 160.21 ? 44 PRO C O 1 ATOM 6926 C CB . PRO C 3 44 ? -52.515 49.265 -24.643 1.00 153.63 ? 44 PRO C CB 1 ATOM 6927 C CG . PRO C 3 44 ? -53.809 49.988 -24.779 1.00 159.11 ? 44 PRO C CG 1 ATOM 6928 C CD . PRO C 3 44 ? -53.903 50.361 -26.227 1.00 165.53 ? 44 PRO C CD 1 ATOM 6929 N N . LYS C 3 45 ? -49.514 48.662 -25.559 1.00 151.38 ? 45 LYS C N 1 ATOM 6930 C CA . LYS C 3 45 ? -48.526 47.697 -26.035 1.00 145.28 ? 45 LYS C CA 1 ATOM 6931 C C . LYS C 3 45 ? -47.935 46.897 -24.874 1.00 140.42 ? 45 LYS C C 1 ATOM 6932 O O . LYS C 3 45 ? -47.593 47.462 -23.835 1.00 142.90 ? 45 LYS C O 1 ATOM 6933 C CB . LYS C 3 45 ? -47.414 48.414 -26.806 1.00 150.62 ? 45 LYS C CB 1 ATOM 6934 C CG . LYS C 3 45 ? -46.348 47.495 -27.384 1.00 151.34 ? 45 LYS C CG 1 ATOM 6935 C CD . LYS C 3 45 ? -45.296 48.288 -28.147 1.00 142.18 ? 45 LYS C CD 1 ATOM 6936 C CE . LYS C 3 45 ? -44.182 47.390 -28.657 1.00 131.11 ? 45 LYS C CE 1 ATOM 6937 N NZ . LYS C 3 45 ? -43.145 48.166 -29.390 1.00 135.44 ? 45 LYS C NZ 1 ATOM 6938 N N . LEU C 3 46 ? -47.811 45.584 -25.057 1.00 132.56 ? 46 LEU C N 1 ATOM 6939 C CA . LEU C 3 46 ? -47.300 44.706 -24.004 1.00 134.25 ? 46 LEU C CA 1 ATOM 6940 C C . LEU C 3 46 ? -45.803 44.898 -23.766 1.00 136.98 ? 46 LEU C C 1 ATOM 6941 O O . LEU C 3 46 ? -45.038 45.124 -24.705 1.00 137.91 ? 46 LEU C O 1 ATOM 6942 C CB . LEU C 3 46 ? -47.599 43.235 -24.325 1.00 127.95 ? 46 LEU C CB 1 ATOM 6943 C CG . LEU C 3 46 ? -47.110 42.199 -23.304 1.00 122.94 ? 46 LEU C CG 1 ATOM 6944 C CD1 . LEU C 3 46 ? -47.723 42.447 -21.935 1.00 120.65 ? 46 LEU C CD1 1 ATOM 6945 C CD2 . LEU C 3 46 ? -47.395 40.778 -23.763 1.00 117.30 ? 46 LEU C CD2 1 ATOM 6946 N N . LEU C 3 47 ? -45.397 44.807 -22.502 1.00 136.39 ? 47 LEU C N 1 ATOM 6947 C CA . LEU C 3 47 ? -43.995 44.948 -22.126 1.00 138.65 ? 47 LEU C CA 1 ATOM 6948 C C . LEU C 3 47 ? -43.474 43.691 -21.424 1.00 136.26 ? 47 LEU C C 1 ATOM 6949 O O . LEU C 3 47 ? -42.610 42.991 -21.953 1.00 138.35 ? 47 LEU C O 1 ATOM 6950 C CB . LEU C 3 47 ? -43.805 46.173 -21.230 1.00 138.13 ? 47 LEU C CB 1 ATOM 6951 C CG . LEU C 3 47 ? -44.424 47.486 -21.715 1.00 144.75 ? 47 LEU C CG 1 ATOM 6952 C CD1 . LEU C 3 47 ? -44.117 48.610 -20.737 1.00 148.03 ? 47 LEU C CD1 1 ATOM 6953 C CD2 . LEU C 3 47 ? -43.946 47.842 -23.115 1.00 143.99 ? 47 LEU C CD2 1 ATOM 6954 N N . ILE C 3 48 ? -44.000 43.414 -20.232 1.00 129.02 ? 48 ILE C N 1 ATOM 6955 C CA . ILE C 3 48 ? -43.603 42.236 -19.459 1.00 127.42 ? 48 ILE C CA 1 ATOM 6956 C C . ILE C 3 48 ? -44.819 41.422 -19.017 1.00 127.10 ? 48 ILE C C 1 ATOM 6957 O O . ILE C 3 48 ? -45.743 41.967 -18.415 1.00 131.96 ? 48 ILE C O 1 ATOM 6958 C CB . ILE C 3 48 ? -42.813 42.623 -18.197 1.00 121.33 ? 48 ILE C CB 1 ATOM 6959 C CG1 . ILE C 3 48 ? -41.692 43.608 -18.535 1.00 122.00 ? 48 ILE C CG1 1 ATOM 6960 C CG2 . ILE C 3 48 ? -42.263 41.380 -17.529 1.00 118.95 ? 48 ILE C CG2 1 ATOM 6961 C CD1 . ILE C 3 48 ? -40.791 43.935 -17.364 1.00 131.62 ? 48 ILE C CD1 1 ATOM 6962 N N . TYR C 3 49 ? -44.822 40.124 -19.315 1.00 125.69 ? 49 TYR C N 1 ATOM 6963 C CA . TYR C 3 49 ? -45.981 39.286 -18.999 1.00 121.83 ? 49 TYR C CA 1 ATOM 6964 C C . TYR C 3 49 ? -45.972 38.533 -17.657 1.00 119.91 ? 49 TYR C C 1 ATOM 6965 O O . TYR C 3 49 ? -47.009 38.011 -17.243 1.00 119.46 ? 49 TYR C O 1 ATOM 6966 C CB . TYR C 3 49 ? -46.299 38.326 -20.158 1.00 120.09 ? 49 TYR C CB 1 ATOM 6967 C CG . TYR C 3 49 ? -45.105 37.605 -20.750 1.00 121.34 ? 49 TYR C CG 1 ATOM 6968 C CD1 . TYR C 3 49 ? -44.771 36.321 -20.343 1.00 119.21 ? 49 TYR C CD1 1 ATOM 6969 C CD2 . TYR C 3 49 ? -44.325 38.203 -21.731 1.00 126.31 ? 49 TYR C CD2 1 ATOM 6970 C CE1 . TYR C 3 49 ? -43.686 35.658 -20.888 1.00 120.59 ? 49 TYR C CE1 1 ATOM 6971 C CE2 . TYR C 3 49 ? -43.239 37.551 -22.278 1.00 125.74 ? 49 TYR C CE2 1 ATOM 6972 C CZ . TYR C 3 49 ? -42.925 36.278 -21.855 1.00 123.71 ? 49 TYR C CZ 1 ATOM 6973 O OH . TYR C 3 49 ? -41.845 35.623 -22.399 1.00 133.54 ? 49 TYR C OH 1 ATOM 6974 N N . ALA C 3 50 ? -44.829 38.463 -16.977 1.00 111.07 ? 50 ALA C N 1 ATOM 6975 C CA . ALA C 3 50 ? -44.832 37.913 -15.619 1.00 105.17 ? 50 ALA C CA 1 ATOM 6976 C C . ALA C 3 50 ? -44.205 38.834 -14.573 1.00 110.43 ? 50 ALA C C 1 ATOM 6977 O O . ALA C 3 50 ? -44.908 39.519 -13.831 1.00 110.91 ? 50 ALA C O 1 ATOM 6978 C CB . ALA C 3 50 ? -44.149 36.552 -15.603 1.00 92.85 ? 50 ALA C CB 1 ATOM 6979 N N . ALA C 3 51 ? -42.876 38.828 -14.509 1.00 122.53 ? 51 ALA C N 1 ATOM 6980 C CA . ALA C 3 51 ? -42.124 39.778 -13.695 1.00 124.70 ? 51 ALA C CA 1 ATOM 6981 C C . ALA C 3 51 ? -40.922 40.315 -14.467 1.00 127.37 ? 51 ALA C C 1 ATOM 6982 O O . ALA C 3 51 ? -40.843 41.497 -14.797 1.00 127.10 ? 51 ALA C O 1 ATOM 6983 C CB . ALA C 3 51 ? -41.678 39.133 -12.390 1.00 119.85 ? 51 ALA C CB 1 ATOM 6984 N N . SER C 3 52 ? -39.974 39.413 -14.707 1.00 128.24 ? 52 SER C N 1 ATOM 6985 C CA . SER C 3 52 ? -38.737 39.678 -15.440 1.00 134.15 ? 52 SER C CA 1 ATOM 6986 C C . SER C 3 52 ? -38.802 39.266 -16.915 1.00 132.68 ? 52 SER C C 1 ATOM 6987 O O . SER C 3 52 ? -37.793 39.293 -17.619 1.00 136.26 ? 52 SER C O 1 ATOM 6988 C CB . SER C 3 52 ? -37.560 38.986 -14.749 1.00 134.38 ? 52 SER C CB 1 ATOM 6989 O OG . SER C 3 52 ? -37.861 37.631 -14.465 1.00 131.02 ? 52 SER C OG 1 ATOM 6990 N N . SER C 3 53 ? -39.991 38.890 -17.372 1.00 130.34 ? 53 SER C N 1 ATOM 6991 C CA . SER C 3 53 ? -40.160 38.069 -18.573 1.00 130.16 ? 53 SER C CA 1 ATOM 6992 C C . SER C 3 53 ? -40.190 38.804 -19.918 1.00 133.46 ? 53 SER C C 1 ATOM 6993 O O . SER C 3 53 ? -40.521 38.197 -20.935 1.00 136.98 ? 53 SER C O 1 ATOM 6994 C CB . SER C 3 53 ? -41.404 37.181 -18.437 1.00 130.16 ? 53 SER C CB 1 ATOM 6995 O OG . SER C 3 53 ? -42.565 37.959 -18.196 1.00 128.46 ? 53 SER C OG 1 ATOM 6996 N N . LEU C 3 54 ? -39.861 40.096 -19.923 1.00 135.59 ? 54 LEU C N 1 ATOM 6997 C CA . LEU C 3 54 ? -39.984 40.931 -21.128 1.00 137.08 ? 54 LEU C CA 1 ATOM 6998 C C . LEU C 3 54 ? -39.399 40.332 -22.414 1.00 138.77 ? 54 LEU C C 1 ATOM 6999 O O . LEU C 3 54 ? -38.318 39.745 -22.415 1.00 144.03 ? 54 LEU C O 1 ATOM 7000 C CB . LEU C 3 54 ? -39.395 42.334 -20.898 1.00 143.81 ? 54 LEU C CB 1 ATOM 7001 C CG . LEU C 3 54 ? -38.012 42.647 -20.294 1.00 137.55 ? 54 LEU C CG 1 ATOM 7002 C CD1 . LEU C 3 54 ? -37.050 41.463 -20.195 1.00 123.92 ? 54 LEU C CD1 1 ATOM 7003 C CD2 . LEU C 3 54 ? -37.366 43.776 -21.088 1.00 138.77 ? 54 LEU C CD2 1 ATOM 7004 N N . GLN C 3 55 ? -40.149 40.472 -23.503 1.00 132.89 ? 55 GLN C N 1 ATOM 7005 C CA . GLN C 3 55 ? -39.802 39.843 -24.777 1.00 144.10 ? 55 GLN C CA 1 ATOM 7006 C C . GLN C 3 55 ? -39.820 40.780 -25.987 1.00 152.66 ? 55 GLN C C 1 ATOM 7007 O O . GLN C 3 55 ? -38.809 40.949 -26.670 1.00 150.24 ? 55 GLN C O 1 ATOM 7008 C CB . GLN C 3 55 ? -40.681 38.619 -25.047 1.00 147.02 ? 55 GLN C CB 1 ATOM 7009 C CG . GLN C 3 55 ? -40.435 37.990 -26.413 1.00 149.38 ? 55 GLN C CG 1 ATOM 7010 C CD . GLN C 3 55 ? -40.827 36.527 -26.468 1.00 137.95 ? 55 GLN C CD 1 ATOM 7011 O OE1 . GLN C 3 55 ? -40.969 35.872 -25.436 1.00 134.47 ? 55 GLN C OE1 1 ATOM 7012 N NE2 . GLN C 3 55 ? -41.010 36.008 -27.676 1.00 128.03 ? 55 GLN C NE2 1 ATOM 7013 N N . SER C 3 56 ? -40.982 41.376 -26.242 1.00 154.10 ? 56 SER C N 1 ATOM 7014 C CA . SER C 3 56 ? -41.316 41.958 -27.542 1.00 151.51 ? 56 SER C CA 1 ATOM 7015 C C . SER C 3 56 ? -40.488 43.189 -27.907 1.00 152.87 ? 56 SER C C 1 ATOM 7016 O O . SER C 3 56 ? -39.559 43.558 -27.190 1.00 159.64 ? 56 SER C O 1 ATOM 7017 C CB . SER C 3 56 ? -42.804 42.317 -27.583 1.00 144.11 ? 56 SER C CB 1 ATOM 7018 O OG . SER C 3 56 ? -43.603 41.250 -27.101 1.00 128.30 ? 56 SER C OG 1 ATOM 7019 N N . GLY C 3 57 ? -40.837 43.810 -29.032 1.00 144.88 ? 57 GLY C N 1 ATOM 7020 C CA . GLY C 3 57 ? -40.035 44.856 -29.649 1.00 146.78 ? 57 GLY C CA 1 ATOM 7021 C C . GLY C 3 57 ? -39.577 45.982 -28.741 1.00 157.52 ? 57 GLY C C 1 ATOM 7022 O O . GLY C 3 57 ? -38.566 46.629 -29.016 1.00 158.54 ? 57 GLY C O 1 ATOM 7023 N N . VAL C 3 58 ? -40.329 46.228 -27.672 1.00 163.12 ? 58 VAL C N 1 ATOM 7024 C CA . VAL C 3 58 ? -39.914 47.159 -26.627 1.00 166.11 ? 58 VAL C CA 1 ATOM 7025 C C . VAL C 3 58 ? -38.526 46.772 -26.100 1.00 163.89 ? 58 VAL C C 1 ATOM 7026 O O . VAL C 3 58 ? -38.261 45.596 -25.854 1.00 160.95 ? 58 VAL C O 1 ATOM 7027 C CB . VAL C 3 58 ? -40.954 47.191 -25.477 1.00 163.17 ? 58 VAL C CB 1 ATOM 7028 C CG1 . VAL C 3 58 ? -41.348 45.777 -25.068 1.00 156.24 ? 58 VAL C CG1 1 ATOM 7029 C CG2 . VAL C 3 58 ? -40.441 47.987 -24.283 1.00 163.76 ? 58 VAL C CG2 1 ATOM 7030 N N . PRO C 3 59 ? -37.631 47.763 -25.938 1.00 163.83 ? 59 PRO C N 1 ATOM 7031 C CA . PRO C 3 59 ? -36.227 47.530 -25.571 1.00 163.41 ? 59 PRO C CA 1 ATOM 7032 C C . PRO C 3 59 ? -36.022 46.728 -24.283 1.00 157.18 ? 59 PRO C C 1 ATOM 7033 O O . PRO C 3 59 ? -36.925 46.626 -23.451 1.00 156.74 ? 59 PRO C O 1 ATOM 7034 C CB . PRO C 3 59 ? -35.680 48.947 -25.398 1.00 166.63 ? 59 PRO C CB 1 ATOM 7035 C CG . PRO C 3 59 ? -36.481 49.758 -26.347 1.00 170.26 ? 59 PRO C CG 1 ATOM 7036 C CD . PRO C 3 59 ? -37.867 49.170 -26.316 1.00 164.51 ? 59 PRO C CD 1 ATOM 7037 N N . SER C 3 60 ? -34.827 46.162 -24.139 1.00 155.74 ? 60 SER C N 1 ATOM 7038 C CA . SER C 3 60 ? -34.510 45.251 -23.043 1.00 154.87 ? 60 SER C CA 1 ATOM 7039 C C . SER C 3 60 ? -34.100 45.977 -21.765 1.00 152.67 ? 60 SER C C 1 ATOM 7040 O O . SER C 3 60 ? -33.745 45.341 -20.771 1.00 149.67 ? 60 SER C O 1 ATOM 7041 C CB . SER C 3 60 ? -33.403 44.282 -23.465 1.00 152.75 ? 60 SER C CB 1 ATOM 7042 O OG . SER C 3 60 ? -32.213 44.980 -23.792 1.00 149.05 ? 60 SER C OG 1 ATOM 7043 N N . ARG C 3 61 ? -34.137 47.306 -21.803 1.00 154.72 ? 61 ARG C N 1 ATOM 7044 C CA . ARG C 3 61 ? -33.799 48.131 -20.646 1.00 156.61 ? 61 ARG C CA 1 ATOM 7045 C C . ARG C 3 61 ? -34.666 47.793 -19.435 1.00 165.45 ? 61 ARG C C 1 ATOM 7046 O O . ARG C 3 61 ? -34.196 47.799 -18.297 1.00 165.85 ? 61 ARG C O 1 ATOM 7047 C CB . ARG C 3 61 ? -33.971 49.614 -20.987 1.00 157.05 ? 61 ARG C CB 1 ATOM 7048 C CG . ARG C 3 61 ? -33.297 50.051 -22.278 1.00 158.58 ? 61 ARG C CG 1 ATOM 7049 C CD . ARG C 3 61 ? -33.439 51.554 -22.489 1.00 158.37 ? 61 ARG C CD 1 ATOM 7050 N NE . ARG C 3 61 ? -34.830 51.965 -22.667 1.00 155.86 ? 61 ARG C NE 1 ATOM 7051 C CZ . ARG C 3 61 ? -35.378 52.260 -23.842 1.00 156.62 ? 61 ARG C CZ 1 ATOM 7052 N NH1 . ARG C 3 61 ? -34.651 52.197 -24.949 1.00 151.57 ? 61 ARG C NH1 1 ATOM 7053 N NH2 . ARG C 3 61 ? -36.651 52.625 -23.909 1.00 160.59 ? 61 ARG C NH2 1 ATOM 7054 N N . PHE C 3 62 ? -35.935 47.495 -19.696 1.00 166.10 ? 62 PHE C N 1 ATOM 7055 C CA . PHE C 3 62 ? -36.922 47.268 -18.645 1.00 157.67 ? 62 PHE C CA 1 ATOM 7056 C C . PHE C 3 62 ? -36.711 45.948 -17.901 1.00 155.38 ? 62 PHE C C 1 ATOM 7057 O O . PHE C 3 62 ? -36.059 45.034 -18.407 1.00 160.65 ? 62 PHE C O 1 ATOM 7058 C CB . PHE C 3 62 ? -38.337 47.321 -19.231 1.00 156.01 ? 62 PHE C CB 1 ATOM 7059 C CG . PHE C 3 62 ? -38.668 48.626 -19.907 1.00 162.77 ? 62 PHE C CG 1 ATOM 7060 C CD1 . PHE C 3 62 ? -39.378 49.607 -19.236 1.00 168.22 ? 62 PHE C CD1 1 ATOM 7061 C CD2 . PHE C 3 62 ? -38.275 48.868 -21.214 1.00 162.59 ? 62 PHE C CD2 1 ATOM 7062 C CE1 . PHE C 3 62 ? -39.687 50.806 -19.854 1.00 171.00 ? 62 PHE C CE1 1 ATOM 7063 C CE2 . PHE C 3 62 ? -38.579 50.065 -21.836 1.00 164.28 ? 62 PHE C CE2 1 ATOM 7064 C CZ . PHE C 3 62 ? -39.286 51.034 -21.155 1.00 170.19 ? 62 PHE C CZ 1 ATOM 7065 N N . SER C 3 63 ? -37.269 45.862 -16.696 1.00 152.21 ? 63 SER C N 1 ATOM 7066 C CA . SER C 3 63 ? -37.174 44.658 -15.873 1.00 152.78 ? 63 SER C CA 1 ATOM 7067 C C . SER C 3 63 ? -38.296 44.624 -14.836 1.00 154.27 ? 63 SER C C 1 ATOM 7068 O O . SER C 3 63 ? -39.185 45.474 -14.851 1.00 154.05 ? 63 SER C O 1 ATOM 7069 C CB . SER C 3 63 ? -35.811 44.584 -15.183 1.00 150.14 ? 63 SER C CB 1 ATOM 7070 O OG . SER C 3 63 ? -35.557 45.755 -14.427 1.00 153.10 ? 63 SER C OG 1 ATOM 7071 N N . GLY C 3 64 ? -38.255 43.640 -13.942 1.00 149.59 ? 64 GLY C N 1 ATOM 7072 C CA . GLY C 3 64 ? -39.264 43.519 -12.903 1.00 144.53 ? 64 GLY C CA 1 ATOM 7073 C C . GLY C 3 64 ? -39.022 42.374 -11.935 1.00 143.78 ? 64 GLY C C 1 ATOM 7074 O O . GLY C 3 64 ? -38.270 41.447 -12.236 1.00 146.02 ? 64 GLY C O 1 ATOM 7075 N N . SER C 3 65 ? -39.666 42.439 -10.771 1.00 143.72 ? 65 SER C N 1 ATOM 7076 C CA . SER C 3 65 ? -39.502 41.419 -9.737 1.00 147.97 ? 65 SER C CA 1 ATOM 7077 C C . SER C 3 65 ? -40.620 41.468 -8.693 1.00 151.35 ? 65 SER C C 1 ATOM 7078 O O . SER C 3 65 ? -41.600 42.196 -8.852 1.00 151.49 ? 65 SER C O 1 ATOM 7079 C CB . SER C 3 65 ? -38.145 41.569 -9.048 1.00 148.19 ? 65 SER C CB 1 ATOM 7080 O OG . SER C 3 65 ? -38.050 42.815 -8.381 1.00 149.50 ? 65 SER C OG 1 ATOM 7081 N N . GLY C 3 66 ? -40.462 40.684 -7.629 1.00 152.37 ? 66 GLY C N 1 ATOM 7082 C CA . GLY C 3 66 ? -41.415 40.651 -6.531 1.00 160.26 ? 66 GLY C CA 1 ATOM 7083 C C . GLY C 3 66 ? -42.269 39.396 -6.509 1.00 162.40 ? 66 GLY C C 1 ATOM 7084 O O . GLY C 3 66 ? -42.483 38.769 -7.546 1.00 157.65 ? 66 GLY C O 1 ATOM 7085 N N . SER C 3 67 ? -42.748 39.017 -5.325 1.00 165.35 ? 67 SER C N 1 ATOM 7086 C CA . SER C 3 67 ? -43.612 37.844 -5.201 1.00 158.75 ? 67 SER C CA 1 ATOM 7087 C C . SER C 3 67 ? -44.641 37.921 -4.070 1.00 154.75 ? 67 SER C C 1 ATOM 7088 O O . SER C 3 67 ? -44.341 38.379 -2.968 1.00 158.81 ? 67 SER C O 1 ATOM 7089 C CB . SER C 3 67 ? -42.764 36.581 -5.032 1.00 172.40 ? 67 SER C CB 1 ATOM 7090 O OG . SER C 3 67 ? -43.567 35.473 -4.662 1.00 172.99 ? 67 SER C OG 1 ATOM 7091 N N . GLY C 3 68 ? -45.857 37.473 -4.369 1.00 152.56 ? 68 GLY C N 1 ATOM 7092 C CA . GLY C 3 68 ? -46.856 37.141 -3.367 1.00 151.88 ? 68 GLY C CA 1 ATOM 7093 C C . GLY C 3 68 ? -47.737 38.273 -2.875 1.00 145.44 ? 68 GLY C C 1 ATOM 7094 O O . GLY C 3 68 ? -48.866 38.043 -2.442 1.00 135.59 ? 68 GLY C O 1 ATOM 7095 N N . THR C 3 69 ? -47.228 39.498 -2.945 1.00 153.29 ? 69 THR C N 1 ATOM 7096 C CA . THR C 3 69 ? -47.998 40.671 -2.547 1.00 151.30 ? 69 THR C CA 1 ATOM 7097 C C . THR C 3 69 ? -47.888 41.784 -3.582 1.00 152.63 ? 69 THR C C 1 ATOM 7098 O O . THR C 3 69 ? -48.860 42.128 -4.254 1.00 145.47 ? 69 THR C O 1 ATOM 7099 C CB . THR C 3 69 ? -47.556 41.206 -1.170 1.00 149.85 ? 69 THR C CB 1 ATOM 7100 O OG1 . THR C 3 69 ? -46.126 41.286 -1.123 1.00 150.37 ? 69 THR C OG1 1 ATOM 7101 C CG2 . THR C 3 69 ? -48.044 40.289 -0.058 1.00 146.08 ? 69 THR C CG2 1 ATOM 7102 N N . ASP C 3 70 ? -46.687 42.342 -3.697 1.00 154.85 ? 70 ASP C N 1 ATOM 7103 C CA . ASP C 3 70 ? -46.430 43.445 -4.612 1.00 151.62 ? 70 ASP C CA 1 ATOM 7104 C C . ASP C 3 70 ? -45.416 43.047 -5.678 1.00 152.07 ? 70 ASP C C 1 ATOM 7105 O O . ASP C 3 70 ? -44.507 42.256 -5.423 1.00 148.07 ? 70 ASP C O 1 ATOM 7106 C CB . ASP C 3 70 ? -45.932 44.668 -3.840 1.00 146.42 ? 70 ASP C CB 1 ATOM 7107 C CG . ASP C 3 70 ? -46.901 45.106 -2.761 1.00 148.38 ? 70 ASP C CG 1 ATOM 7108 O OD1 . ASP C 3 70 ? -48.125 44.983 -2.975 1.00 148.84 ? 70 ASP C OD1 1 ATOM 7109 O OD2 . ASP C 3 70 ? -46.439 45.568 -1.697 1.00 147.72 ? 70 ASP C OD2 1 ATOM 7110 N N . PHE C 3 71 ? -45.584 43.596 -6.876 1.00 158.34 ? 71 PHE C N 1 ATOM 7111 C CA . PHE C 3 71 ? -44.711 43.283 -8.001 1.00 162.48 ? 71 PHE C CA 1 ATOM 7112 C C . PHE C 3 71 ? -44.288 44.575 -8.693 1.00 164.35 ? 71 PHE C C 1 ATOM 7113 O O . PHE C 3 71 ? -45.129 45.383 -9.087 1.00 162.67 ? 71 PHE C O 1 ATOM 7114 C CB . PHE C 3 71 ? -45.418 42.345 -8.984 1.00 157.21 ? 71 PHE C CB 1 ATOM 7115 C CG . PHE C 3 71 ? -45.938 41.080 -8.353 1.00 155.81 ? 71 PHE C CG 1 ATOM 7116 C CD1 . PHE C 3 71 ? -47.158 41.066 -7.694 1.00 151.59 ? 71 PHE C CD1 1 ATOM 7117 C CD2 . PHE C 3 71 ? -45.210 39.904 -8.424 1.00 153.25 ? 71 PHE C CD2 1 ATOM 7118 C CE1 . PHE C 3 71 ? -47.637 39.909 -7.111 1.00 147.10 ? 71 PHE C CE1 1 ATOM 7119 C CE2 . PHE C 3 71 ? -45.687 38.742 -7.845 1.00 149.58 ? 71 PHE C CE2 1 ATOM 7120 C CZ . PHE C 3 71 ? -46.902 38.746 -7.188 1.00 148.81 ? 71 PHE C CZ 1 ATOM 7121 N N . THR C 3 72 ? -42.981 44.760 -8.845 1.00 161.90 ? 72 THR C N 1 ATOM 7122 C CA . THR C 3 72 ? -42.435 46.042 -9.282 1.00 160.38 ? 72 THR C CA 1 ATOM 7123 C C . THR C 3 72 ? -41.952 46.060 -10.732 1.00 162.48 ? 72 THR C C 1 ATOM 7124 O O . THR C 3 72 ? -41.492 45.049 -11.259 1.00 163.62 ? 72 THR C O 1 ATOM 7125 C CB . THR C 3 72 ? -41.277 46.490 -8.367 1.00 154.13 ? 72 THR C CB 1 ATOM 7126 O OG1 . THR C 3 72 ? -40.612 47.617 -8.950 1.00 154.65 ? 72 THR C OG1 1 ATOM 7127 C CG2 . THR C 3 72 ? -40.275 45.360 -8.182 1.00 149.42 ? 72 THR C CG2 1 ATOM 7128 N N . LEU C 3 73 ? -42.081 47.222 -11.369 1.00 162.27 ? 73 LEU C N 1 ATOM 7129 C CA . LEU C 3 73 ? -41.504 47.465 -12.687 1.00 158.50 ? 73 LEU C CA 1 ATOM 7130 C C . LEU C 3 73 ? -40.362 48.466 -12.557 1.00 162.56 ? 73 LEU C C 1 ATOM 7131 O O . LEU C 3 73 ? -40.542 49.549 -12.002 1.00 167.52 ? 73 LEU C O 1 ATOM 7132 C CB . LEU C 3 73 ? -42.559 48.011 -13.650 1.00 150.78 ? 73 LEU C CB 1 ATOM 7133 C CG . LEU C 3 73 ? -42.044 48.701 -14.918 1.00 147.89 ? 73 LEU C CG 1 ATOM 7134 C CD1 . LEU C 3 73 ? -41.358 47.712 -15.847 1.00 148.60 ? 73 LEU C CD1 1 ATOM 7135 C CD2 . LEU C 3 73 ? -43.171 49.424 -15.641 1.00 155.26 ? 73 LEU C CD2 1 ATOM 7136 N N . THR C 3 74 ? -39.189 48.103 -13.065 1.00 163.17 ? 74 THR C N 1 ATOM 7137 C CA . THR C 3 74 ? -38.020 48.971 -12.967 1.00 165.31 ? 74 THR C CA 1 ATOM 7138 C C . THR C 3 74 ? -37.393 49.252 -14.332 1.00 166.23 ? 74 THR C C 1 ATOM 7139 O O . THR C 3 74 ? -37.006 48.329 -15.048 1.00 165.77 ? 74 THR C O 1 ATOM 7140 C CB . THR C 3 74 ? -36.941 48.371 -12.036 1.00 164.06 ? 74 THR C CB 1 ATOM 7141 O OG1 . THR C 3 74 ? -36.438 47.154 -12.602 1.00 165.60 ? 74 THR C OG1 1 ATOM 7142 C CG2 . THR C 3 74 ? -37.516 48.086 -10.655 1.00 158.15 ? 74 THR C CG2 1 ATOM 7143 N N . ILE C 3 75 ? -37.296 50.531 -14.685 1.00 163.30 ? 75 ILE C N 1 ATOM 7144 C CA . ILE C 3 75 ? -36.616 50.937 -15.909 1.00 160.53 ? 75 ILE C CA 1 ATOM 7145 C C . ILE C 3 75 ? -35.164 51.268 -15.582 1.00 167.53 ? 75 ILE C C 1 ATOM 7146 O O . ILE C 3 75 ? -34.888 52.243 -14.883 1.00 171.04 ? 75 ILE C O 1 ATOM 7147 C CB . ILE C 3 75 ? -37.285 52.171 -16.552 1.00 157.31 ? 75 ILE C CB 1 ATOM 7148 C CG1 . ILE C 3 75 ? -38.803 51.992 -16.616 1.00 162.21 ? 75 ILE C CG1 1 ATOM 7149 C CG2 . ILE C 3 75 ? -36.716 52.428 -17.941 1.00 159.06 ? 75 ILE C CG2 1 ATOM 7150 C CD1 . ILE C 3 75 ? -39.537 53.189 -17.192 1.00 164.15 ? 75 ILE C CD1 1 ATOM 7151 N N . SER C 3 76 ? -34.241 50.451 -16.082 1.00 168.18 ? 76 SER C N 1 ATOM 7152 C CA . SER C 3 76 ? -32.820 50.621 -15.792 1.00 162.94 ? 76 SER C CA 1 ATOM 7153 C C . SER C 3 76 ? -32.288 51.952 -16.316 1.00 164.32 ? 76 SER C C 1 ATOM 7154 O O . SER C 3 76 ? -31.600 52.681 -15.602 1.00 160.91 ? 76 SER C O 1 ATOM 7155 C CB . SER C 3 76 ? -32.013 49.459 -16.373 1.00 160.19 ? 76 SER C CB 1 ATOM 7156 O OG . SER C 3 76 ? -32.292 49.285 -17.752 1.00 158.84 ? 76 SER C OG 1 ATOM 7157 N N . SER C 3 77 ? -32.615 52.262 -17.567 1.00 167.35 ? 77 SER C N 1 ATOM 7158 C CA . SER C 3 77 ? -32.217 53.526 -18.177 1.00 168.95 ? 77 SER C CA 1 ATOM 7159 C C . SER C 3 77 ? -33.408 54.200 -18.849 1.00 168.92 ? 77 SER C C 1 ATOM 7160 O O . SER C 3 77 ? -33.988 53.657 -19.790 1.00 167.43 ? 77 SER C O 1 ATOM 7161 C CB . SER C 3 77 ? -31.096 53.303 -19.195 1.00 169.08 ? 77 SER C CB 1 ATOM 7162 O OG . SER C 3 77 ? -30.737 54.517 -19.833 1.00 167.63 ? 77 SER C OG 1 ATOM 7163 N N . LEU C 3 78 ? -33.770 55.384 -18.366 1.00 170.03 ? 78 LEU C N 1 ATOM 7164 C CA . LEU C 3 78 ? -34.912 56.109 -18.913 1.00 171.30 ? 78 LEU C CA 1 ATOM 7165 C C . LEU C 3 78 ? -34.561 56.774 -20.242 1.00 167.60 ? 78 LEU C C 1 ATOM 7166 O O . LEU C 3 78 ? -33.445 57.259 -20.430 1.00 163.19 ? 78 LEU C O 1 ATOM 7167 C CB . LEU C 3 78 ? -35.429 57.146 -17.910 1.00 169.85 ? 78 LEU C CB 1 ATOM 7168 C CG . LEU C 3 78 ? -36.771 57.801 -18.247 1.00 167.23 ? 78 LEU C CG 1 ATOM 7169 C CD1 . LEU C 3 78 ? -37.798 56.745 -18.612 1.00 161.17 ? 78 LEU C CD1 1 ATOM 7170 C CD2 . LEU C 3 78 ? -37.273 58.647 -17.087 1.00 167.66 ? 78 LEU C CD2 1 ATOM 7171 N N . GLN C 3 79 ? -35.519 56.781 -21.164 1.00 168.47 ? 79 GLN C N 1 ATOM 7172 C CA . GLN C 3 79 ? -35.326 57.380 -22.479 1.00 167.24 ? 79 GLN C CA 1 ATOM 7173 C C . GLN C 3 79 ? -36.482 58.323 -22.806 1.00 171.74 ? 79 GLN C C 1 ATOM 7174 O O . GLN C 3 79 ? -37.588 58.145 -22.300 1.00 176.71 ? 79 GLN C O 1 ATOM 7175 C CB . GLN C 3 79 ? -35.210 56.287 -23.547 1.00 167.68 ? 79 GLN C CB 1 ATOM 7176 C CG . GLN C 3 79 ? -33.966 55.420 -23.420 1.00 166.55 ? 79 GLN C CG 1 ATOM 7177 C CD . GLN C 3 79 ? -32.691 56.173 -23.748 1.00 166.51 ? 79 GLN C CD 1 ATOM 7178 O OE1 . GLN C 3 79 ? -32.720 57.210 -24.411 1.00 168.41 ? 79 GLN C OE1 1 ATOM 7179 N NE2 . GLN C 3 79 ? -31.561 55.652 -23.285 1.00 162.13 ? 79 GLN C NE2 1 ATOM 7180 N N . PRO C 3 80 ? -36.226 59.340 -23.645 1.00 175.93 ? 80 PRO C N 1 ATOM 7181 C CA . PRO C 3 80 ? -37.254 60.316 -24.031 1.00 183.21 ? 80 PRO C CA 1 ATOM 7182 C C . PRO C 3 80 ? -38.453 59.699 -24.756 1.00 184.49 ? 80 PRO C C 1 ATOM 7183 O O . PRO C 3 80 ? -39.505 60.334 -24.837 1.00 184.82 ? 80 PRO C O 1 ATOM 7184 C CB . PRO C 3 80 ? -36.500 61.258 -24.974 1.00 183.23 ? 80 PRO C CB 1 ATOM 7185 C CG . PRO C 3 80 ? -35.081 61.156 -24.546 1.00 177.09 ? 80 PRO C CG 1 ATOM 7186 C CD . PRO C 3 80 ? -34.893 59.724 -24.141 1.00 174.19 ? 80 PRO C CD 1 ATOM 7187 N N . GLU C 3 81 ? -38.294 58.485 -25.273 1.00 182.50 ? 81 GLU C N 1 ATOM 7188 C CA . GLU C 3 81 ? -39.372 57.807 -25.989 1.00 182.67 ? 81 GLU C CA 1 ATOM 7189 C C . GLU C 3 81 ? -40.232 56.978 -25.039 1.00 178.21 ? 81 GLU C C 1 ATOM 7190 O O . GLU C 3 81 ? -41.139 56.263 -25.466 1.00 175.15 ? 81 GLU C O 1 ATOM 7191 C CB . GLU C 3 81 ? -38.811 56.927 -27.111 1.00 186.88 ? 81 GLU C CB 1 ATOM 7192 C CG . GLU C 3 81 ? -37.966 55.753 -26.635 1.00 187.18 ? 81 GLU C CG 1 ATOM 7193 C CD . GLU C 3 81 ? -37.369 54.959 -27.785 1.00 179.51 ? 81 GLU C CD 1 ATOM 7194 O OE1 . GLU C 3 81 ? -37.164 55.542 -28.870 1.00 175.30 ? 81 GLU C OE1 1 ATOM 7195 O OE2 . GLU C 3 81 ? -37.109 53.750 -27.605 1.00 171.89 ? 81 GLU C OE2 1 ATOM 7196 N N . ASP C 3 82 ? -39.935 57.082 -23.747 1.00 180.60 ? 82 ASP C N 1 ATOM 7197 C CA . ASP C 3 82 ? -40.632 56.316 -22.719 1.00 181.39 ? 82 ASP C CA 1 ATOM 7198 C C . ASP C 3 82 ? -41.823 57.056 -22.107 1.00 179.84 ? 82 ASP C C 1 ATOM 7199 O O . ASP C 3 82 ? -42.412 56.583 -21.135 1.00 176.09 ? 82 ASP C O 1 ATOM 7200 C CB . ASP C 3 82 ? -39.662 55.879 -21.618 1.00 178.17 ? 82 ASP C CB 1 ATOM 7201 C CG . ASP C 3 82 ? -38.559 54.978 -22.137 1.00 172.11 ? 82 ASP C CG 1 ATOM 7202 O OD1 . ASP C 3 82 ? -38.241 55.059 -23.342 1.00 168.04 ? 82 ASP C OD1 1 ATOM 7203 O OD2 . ASP C 3 82 ? -38.008 54.190 -21.339 1.00 167.55 ? 82 ASP C OD2 1 ATOM 7204 N N . PHE C 3 83 ? -42.176 58.214 -22.659 1.00 180.56 ? 83 PHE C N 1 ATOM 7205 C CA . PHE C 3 83 ? -43.265 58.996 -22.083 1.00 181.24 ? 83 PHE C CA 1 ATOM 7206 C C . PHE C 3 83 ? -44.605 58.373 -22.449 1.00 181.89 ? 83 PHE C C 1 ATOM 7207 O O . PHE C 3 83 ? -44.982 58.316 -23.621 1.00 172.90 ? 83 PHE C O 1 ATOM 7208 C CB . PHE C 3 83 ? -43.211 60.446 -22.581 1.00 182.47 ? 83 PHE C CB 1 ATOM 7209 C CG . PHE C 3 83 ? -44.434 61.258 -22.234 1.00 187.31 ? 83 PHE C CG 1 ATOM 7210 C CD1 . PHE C 3 83 ? -44.557 61.852 -20.990 1.00 187.28 ? 83 PHE C CD1 1 ATOM 7211 C CD2 . PHE C 3 83 ? -45.452 61.439 -23.158 1.00 184.74 ? 83 PHE C CD2 1 ATOM 7212 C CE1 . PHE C 3 83 ? -45.676 62.599 -20.667 1.00 183.21 ? 83 PHE C CE1 1 ATOM 7213 C CE2 . PHE C 3 83 ? -46.574 62.186 -22.841 1.00 181.95 ? 83 PHE C CE2 1 ATOM 7214 C CZ . PHE C 3 83 ? -46.685 62.767 -21.594 1.00 179.94 ? 83 PHE C CZ 1 ATOM 7215 N N . ALA C 3 84 ? -45.320 57.925 -21.420 1.00 183.06 ? 84 ALA C N 1 ATOM 7216 C CA . ALA C 3 84 ? -46.614 57.269 -21.568 1.00 173.69 ? 84 ALA C CA 1 ATOM 7217 C C . ALA C 3 84 ? -47.227 57.060 -20.190 1.00 173.36 ? 84 ALA C C 1 ATOM 7218 O O . ALA C 3 84 ? -46.655 57.469 -19.179 1.00 173.84 ? 84 ALA C O 1 ATOM 7219 C CB . ALA C 3 84 ? -46.460 55.936 -22.282 1.00 168.56 ? 84 ALA C CB 1 ATOM 7220 N N . THR C 3 85 ? -48.390 56.420 -20.151 1.00 170.53 ? 85 THR C N 1 ATOM 7221 C CA . THR C 3 85 ? -48.981 55.995 -18.889 1.00 169.91 ? 85 THR C CA 1 ATOM 7222 C C . THR C 3 85 ? -48.812 54.485 -18.749 1.00 167.67 ? 85 THR C C 1 ATOM 7223 O O . THR C 3 85 ? -48.874 53.757 -19.739 1.00 166.39 ? 85 THR C O 1 ATOM 7224 C CB . THR C 3 85 ? -50.473 56.365 -18.798 1.00 169.31 ? 85 THR C CB 1 ATOM 7225 O OG1 . THR C 3 85 ? -51.191 55.736 -19.867 1.00 168.92 ? 85 THR C OG1 1 ATOM 7226 C CG2 . THR C 3 85 ? -50.654 57.873 -18.891 1.00 168.85 ? 85 THR C CG2 1 ATOM 7227 N N . TYR C 3 86 ? -48.590 54.015 -17.526 1.00 170.07 ? 86 TYR C N 1 ATOM 7228 C CA . TYR C 3 86 ? -48.347 52.592 -17.301 1.00 169.64 ? 86 TYR C CA 1 ATOM 7229 C C . TYR C 3 86 ? -49.428 51.904 -16.468 1.00 170.91 ? 86 TYR C C 1 ATOM 7230 O O . TYR C 3 86 ? -49.598 52.193 -15.284 1.00 174.04 ? 86 TYR C O 1 ATOM 7231 C CB . TYR C 3 86 ? -46.966 52.372 -16.676 1.00 162.77 ? 86 TYR C CB 1 ATOM 7232 C CG . TYR C 3 86 ? -45.821 52.621 -17.632 1.00 166.69 ? 86 TYR C CG 1 ATOM 7233 C CD1 . TYR C 3 86 ? -45.148 53.836 -17.644 1.00 172.25 ? 86 TYR C CD1 1 ATOM 7234 C CD2 . TYR C 3 86 ? -45.418 51.642 -18.530 1.00 165.45 ? 86 TYR C CD2 1 ATOM 7235 C CE1 . TYR C 3 86 ? -44.102 54.066 -18.520 1.00 171.64 ? 86 TYR C CE1 1 ATOM 7236 C CE2 . TYR C 3 86 ? -44.375 51.863 -19.410 1.00 161.96 ? 86 TYR C CE2 1 ATOM 7237 C CZ . TYR C 3 86 ? -43.720 53.075 -19.401 1.00 162.36 ? 86 TYR C CZ 1 ATOM 7238 O OH . TYR C 3 86 ? -42.682 53.296 -20.276 1.00 151.35 ? 86 TYR C OH 1 ATOM 7239 N N . TYR C 3 87 ? -50.150 50.985 -17.103 1.00 162.34 ? 87 TYR C N 1 ATOM 7240 C CA . TYR C 3 87 ? -51.166 50.187 -16.427 1.00 156.85 ? 87 TYR C CA 1 ATOM 7241 C C . TYR C 3 87 ? -50.637 48.785 -16.153 1.00 149.29 ? 87 TYR C C 1 ATOM 7242 O O . TYR C 3 87 ? -49.850 48.249 -16.932 1.00 147.47 ? 87 TYR C O 1 ATOM 7243 C CB . TYR C 3 87 ? -52.430 50.086 -17.282 1.00 162.78 ? 87 TYR C CB 1 ATOM 7244 C CG . TYR C 3 87 ? -53.107 51.405 -17.576 1.00 169.50 ? 87 TYR C CG 1 ATOM 7245 C CD1 . TYR C 3 87 ? -52.755 52.154 -18.691 1.00 166.51 ? 87 TYR C CD1 1 ATOM 7246 C CD2 . TYR C 3 87 ? -54.111 51.891 -16.750 1.00 170.54 ? 87 TYR C CD2 1 ATOM 7247 C CE1 . TYR C 3 87 ? -53.377 53.355 -18.969 1.00 168.80 ? 87 TYR C CE1 1 ATOM 7248 C CE2 . TYR C 3 87 ? -54.738 53.092 -17.019 1.00 170.76 ? 87 TYR C CE2 1 ATOM 7249 C CZ . TYR C 3 87 ? -54.367 53.820 -18.130 1.00 172.36 ? 87 TYR C CZ 1 ATOM 7250 O OH . TYR C 3 87 ? -54.988 55.016 -18.404 1.00 171.90 ? 87 TYR C OH 1 ATOM 7251 N N . CYS C 3 88 ? -51.063 48.196 -15.040 1.00 144.68 ? 88 CYS C N 1 ATOM 7252 C CA . CYS C 3 88 ? -50.701 46.820 -14.722 1.00 136.97 ? 88 CYS C CA 1 ATOM 7253 C C . CYS C 3 88 ? -51.931 45.919 -14.645 1.00 136.55 ? 88 CYS C C 1 ATOM 7254 O O . CYS C 3 88 ? -53.035 46.380 -14.359 1.00 139.25 ? 88 CYS C O 1 ATOM 7255 C CB . CYS C 3 88 ? -49.907 46.755 -13.415 1.00 132.32 ? 88 CYS C CB 1 ATOM 7256 S SG . CYS C 3 88 ? -50.645 47.659 -12.038 1.00 165.74 ? 88 CYS C SG 1 ATOM 7257 N N . GLN C 3 89 ? -51.729 44.632 -14.911 1.00 129.51 ? 89 GLN C N 1 ATOM 7258 C CA . GLN C 3 89 ? -52.806 43.652 -14.855 1.00 120.23 ? 89 GLN C CA 1 ATOM 7259 C C . GLN C 3 89 ? -52.417 42.497 -13.940 1.00 116.88 ? 89 GLN C C 1 ATOM 7260 O O . GLN C 3 89 ? -51.253 42.105 -13.888 1.00 119.22 ? 89 GLN C O 1 ATOM 7261 C CB . GLN C 3 89 ? -53.119 43.126 -16.259 1.00 114.59 ? 89 GLN C CB 1 ATOM 7262 C CG . GLN C 3 89 ? -54.091 41.955 -16.296 1.00 106.94 ? 89 GLN C CG 1 ATOM 7263 C CD . GLN C 3 89 ? -54.152 41.290 -17.657 1.00 107.52 ? 89 GLN C CD 1 ATOM 7264 O OE1 . GLN C 3 89 ? -53.964 41.938 -18.687 1.00 110.89 ? 89 GLN C OE1 1 ATOM 7265 N NE2 . GLN C 3 89 ? -54.409 39.986 -17.668 1.00 99.15 ? 89 GLN C NE2 1 ATOM 7266 N N . GLN C 3 90 ? -53.391 41.962 -13.210 1.00 115.27 ? 90 GLN C N 1 ATOM 7267 C CA . GLN C 3 90 ? -53.159 40.792 -12.372 1.00 119.22 ? 90 GLN C CA 1 ATOM 7268 C C . GLN C 3 90 ? -53.920 39.596 -12.921 1.00 112.70 ? 90 GLN C C 1 ATOM 7269 O O . GLN C 3 90 ? -55.148 39.550 -12.869 1.00 109.76 ? 90 GLN C O 1 ATOM 7270 C CB . GLN C 3 90 ? -53.584 41.068 -10.955 1.00 124.71 ? 90 GLN C CB 1 ATOM 7271 N N . ALA C 3 91 ? -53.187 38.625 -13.448 1.00 107.50 ? 91 ALA C N 1 ATOM 7272 C CA . ALA C 3 91 ? -53.813 37.479 -14.089 1.00 100.51 ? 91 ALA C CA 1 ATOM 7273 C C . ALA C 3 91 ? -53.944 36.243 -13.199 1.00 104.68 ? 91 ALA C C 1 ATOM 7274 O O . ALA C 3 91 ? -54.518 35.247 -13.621 1.00 101.40 ? 91 ALA C O 1 ATOM 7275 C CB . ALA C 3 91 ? -53.072 37.132 -15.362 1.00 94.82 ? 91 ALA C CB 1 ATOM 7276 N N . ASN C 3 92 ? -53.425 36.302 -11.975 1.00 110.36 ? 92 ASN C N 1 ATOM 7277 C CA . ASN C 3 92 ? -53.437 35.134 -11.090 1.00 107.57 ? 92 ASN C CA 1 ATOM 7278 C C . ASN C 3 92 ? -54.837 34.587 -10.801 1.00 102.63 ? 92 ASN C C 1 ATOM 7279 O O . ASN C 3 92 ? -55.035 33.374 -10.729 1.00 99.72 ? 92 ASN C O 1 ATOM 7280 C CB . ASN C 3 92 ? -52.719 35.435 -9.774 1.00 113.89 ? 92 ASN C CB 1 ATOM 7281 C CG . ASN C 3 92 ? -51.208 35.516 -9.926 1.00 125.19 ? 92 ASN C CG 1 ATOM 7282 O OD1 . ASN C 3 92 ? -50.527 34.494 -10.020 1.00 127.10 ? 92 ASN C OD1 1 ATOM 7283 N ND2 . ASN C 3 92 ? -50.675 36.734 -9.924 1.00 122.44 ? 92 ASN C ND2 1 ATOM 7284 N N . ASN C 3 93 ? -55.798 35.488 -10.624 1.00 109.93 ? 93 ASN C N 1 ATOM 7285 C CA . ASN C 3 93 ? -57.194 35.104 -10.432 1.00 107.95 ? 93 ASN C CA 1 ATOM 7286 C C . ASN C 3 93 ? -58.063 35.845 -11.443 1.00 101.86 ? 93 ASN C C 1 ATOM 7287 O O . ASN C 3 93 ? -57.955 37.061 -11.591 1.00 99.81 ? 93 ASN C O 1 ATOM 7288 C CB . ASN C 3 93 ? -57.641 35.395 -9.014 1.00 105.28 ? 93 ASN C CB 1 ATOM 7289 N N . PHE C 3 94 ? -58.927 35.104 -12.131 1.00 103.20 ? 94 PHE C N 1 ATOM 7290 C CA . PHE C 3 94 ? -59.587 35.608 -13.341 1.00 102.99 ? 94 PHE C CA 1 ATOM 7291 C C . PHE C 3 94 ? -60.630 36.748 -13.332 1.00 100.75 ? 94 PHE C C 1 ATOM 7292 O O . PHE C 3 94 ? -60.596 37.572 -14.244 1.00 97.79 ? 94 PHE C O 1 ATOM 7293 C CB . PHE C 3 94 ? -60.086 34.462 -14.230 1.00 97.15 ? 94 PHE C CB 1 ATOM 7294 C CG . PHE C 3 94 ? -60.207 34.847 -15.677 1.00 90.01 ? 94 PHE C CG 1 ATOM 7295 C CD1 . PHE C 3 94 ? -59.093 34.839 -16.502 1.00 94.34 ? 94 PHE C CD1 1 ATOM 7296 C CD2 . PHE C 3 94 ? -61.422 35.245 -16.207 1.00 86.55 ? 94 PHE C CD2 1 ATOM 7297 C CE1 . PHE C 3 94 ? -59.193 35.204 -17.829 1.00 91.82 ? 94 PHE C CE1 1 ATOM 7298 C CE2 . PHE C 3 94 ? -61.526 35.612 -17.535 1.00 91.64 ? 94 PHE C CE2 1 ATOM 7299 C CZ . PHE C 3 94 ? -60.411 35.590 -18.345 1.00 96.87 ? 94 PHE C CZ 1 ATOM 7300 N N . PRO C 3 95 ? -61.525 36.818 -12.318 1.00 110.27 ? 95 PRO C N 1 ATOM 7301 C CA . PRO C 3 95 ? -62.858 37.423 -12.519 1.00 118.18 ? 95 PRO C CA 1 ATOM 7302 C C . PRO C 3 95 ? -62.844 38.728 -13.313 1.00 116.64 ? 95 PRO C C 1 ATOM 7303 O O . PRO C 3 95 ? -63.705 38.932 -14.168 1.00 111.79 ? 95 PRO C O 1 ATOM 7304 C CB . PRO C 3 95 ? -63.341 37.693 -11.087 1.00 122.81 ? 95 PRO C CB 1 ATOM 7305 C CG . PRO C 3 95 ? -62.104 37.705 -10.255 1.00 113.44 ? 95 PRO C CG 1 ATOM 7306 C CD . PRO C 3 95 ? -61.225 36.673 -10.883 1.00 108.55 ? 95 PRO C CD 1 ATOM 7307 N N . LEU C 3 96 ? -61.858 39.570 -13.023 1.00 117.14 ? 96 LEU C N 1 ATOM 7308 C CA . LEU C 3 96 ? -61.466 40.698 -13.858 1.00 118.31 ? 96 LEU C CA 1 ATOM 7309 C C . LEU C 3 96 ? -60.308 41.345 -13.122 1.00 119.31 ? 96 LEU C C 1 ATOM 7310 O O . LEU C 3 96 ? -60.189 41.196 -11.906 1.00 123.39 ? 96 LEU C O 1 ATOM 7311 C CB . LEU C 3 96 ? -62.636 41.687 -14.019 1.00 130.69 ? 96 LEU C CB 1 ATOM 7312 C CG . LEU C 3 96 ? -62.491 43.192 -14.321 1.00 135.85 ? 96 LEU C CG 1 ATOM 7313 C CD1 . LEU C 3 96 ? -61.639 43.506 -15.554 1.00 127.28 ? 96 LEU C CD1 1 ATOM 7314 C CD2 . LEU C 3 96 ? -63.883 43.822 -14.448 1.00 120.85 ? 96 LEU C CD2 1 ATOM 7315 N N . THR C 3 97 ? -59.452 42.058 -13.845 1.00 111.73 ? 97 THR C N 1 ATOM 7316 C CA . THR C 3 97 ? -58.404 42.842 -13.209 1.00 115.43 ? 97 THR C CA 1 ATOM 7317 C C . THR C 3 97 ? -57.863 43.921 -14.132 1.00 118.95 ? 97 THR C C 1 ATOM 7318 O O . THR C 3 97 ? -57.973 43.814 -15.354 1.00 125.78 ? 97 THR C O 1 ATOM 7319 C CB . THR C 3 97 ? -57.221 41.965 -12.746 1.00 116.92 ? 97 THR C CB 1 ATOM 7320 O OG1 . THR C 3 97 ? -57.430 40.609 -13.157 1.00 118.52 ? 97 THR C OG1 1 ATOM 7321 C CG2 . THR C 3 97 ? -57.082 42.019 -11.233 1.00 117.81 ? 97 THR C CG2 1 ATOM 7322 N N . PHE C 3 98 ? -57.277 44.946 -13.516 1.00 120.01 ? 98 PHE C N 1 ATOM 7323 C CA . PHE C 3 98 ? -56.441 45.945 -14.178 1.00 126.72 ? 98 PHE C CA 1 ATOM 7324 C C . PHE C 3 98 ? -55.999 46.965 -13.143 1.00 130.19 ? 98 PHE C C 1 ATOM 7325 O O . PHE C 3 98 ? -56.638 47.119 -12.103 1.00 135.26 ? 98 PHE C O 1 ATOM 7326 C CB . PHE C 3 98 ? -57.175 46.649 -15.320 1.00 131.06 ? 98 PHE C CB 1 ATOM 7327 C CG . PHE C 3 98 ? -56.703 46.232 -16.682 1.00 131.26 ? 98 PHE C CG 1 ATOM 7328 C CD1 . PHE C 3 98 ? -55.350 46.090 -16.944 1.00 120.24 ? 98 PHE C CD1 1 ATOM 7329 C CD2 . PHE C 3 98 ? -57.608 45.963 -17.695 1.00 136.04 ? 98 PHE C CD2 1 ATOM 7330 C CE1 . PHE C 3 98 ? -54.907 45.700 -18.193 1.00 114.00 ? 98 PHE C CE1 1 ATOM 7331 C CE2 . PHE C 3 98 ? -57.172 45.569 -18.946 1.00 132.40 ? 98 PHE C CE2 1 ATOM 7332 C CZ . PHE C 3 98 ? -55.819 45.440 -19.196 1.00 114.92 ? 98 PHE C CZ 1 ATOM 7333 N N . GLY C 3 99 ? -54.923 47.683 -13.442 1.00 129.55 ? 99 GLY C N 1 ATOM 7334 C CA . GLY C 3 99 ? -54.398 48.665 -12.515 1.00 134.09 ? 99 GLY C CA 1 ATOM 7335 C C . GLY C 3 99 ? -55.009 50.023 -12.774 1.00 142.33 ? 99 GLY C C 1 ATOM 7336 O O . GLY C 3 99 ? -55.581 50.259 -13.839 1.00 140.38 ? 99 GLY C O 1 ATOM 7337 N N . GLY C 3 100 ? -54.900 50.913 -11.796 1.00 149.80 ? 100 GLY C N 1 ATOM 7338 C CA . GLY C 3 100 ? -55.364 52.275 -11.966 1.00 159.18 ? 100 GLY C CA 1 ATOM 7339 C C . GLY C 3 100 ? -54.540 52.969 -13.030 1.00 163.13 ? 100 GLY C C 1 ATOM 7340 O O . GLY C 3 100 ? -55.064 53.733 -13.841 1.00 163.74 ? 100 GLY C O 1 ATOM 7341 N N . GLY C 3 101 ? -53.242 52.683 -13.032 1.00 161.18 ? 101 GLY C N 1 ATOM 7342 C CA . GLY C 3 101 ? -52.328 53.262 -13.997 1.00 160.25 ? 101 GLY C CA 1 ATOM 7343 C C . GLY C 3 101 ? -51.430 54.319 -13.387 1.00 161.29 ? 101 GLY C C 1 ATOM 7344 O O . GLY C 3 101 ? -51.781 54.942 -12.386 1.00 158.65 ? 101 GLY C O 1 ATOM 7345 N N . THR C 3 102 ? -50.265 54.518 -13.994 1.00 170.26 ? 102 THR C N 1 ATOM 7346 C CA . THR C 3 102 ? -49.323 55.535 -13.538 1.00 176.32 ? 102 THR C CA 1 ATOM 7347 C C . THR C 3 102 ? -48.747 56.312 -14.716 1.00 178.37 ? 102 THR C C 1 ATOM 7348 O O . THR C 3 102 ? -48.165 55.730 -15.633 1.00 177.03 ? 102 THR C O 1 ATOM 7349 C CB . THR C 3 102 ? -48.168 54.924 -12.719 1.00 171.90 ? 102 THR C CB 1 ATOM 7350 O OG1 . THR C 3 102 ? -48.663 54.474 -11.452 1.00 175.89 ? 102 THR C OG1 1 ATOM 7351 C CG2 . THR C 3 102 ? -47.075 55.956 -12.484 1.00 168.05 ? 102 THR C CG2 1 ATOM 7352 N N . LYS C 3 103 ? -48.914 57.629 -14.684 1.00 180.66 ? 103 LYS C N 1 ATOM 7353 C CA . LYS C 3 103 ? -48.393 58.494 -15.733 1.00 175.29 ? 103 LYS C CA 1 ATOM 7354 C C . LYS C 3 103 ? -46.925 58.801 -15.471 1.00 182.35 ? 103 LYS C C 1 ATOM 7355 O O . LYS C 3 103 ? -46.544 59.133 -14.349 1.00 184.50 ? 103 LYS C O 1 ATOM 7356 C CB . LYS C 3 103 ? -49.187 59.798 -15.782 1.00 171.25 ? 103 LYS C CB 1 ATOM 7357 C CG . LYS C 3 103 ? -50.685 59.624 -15.598 1.00 178.88 ? 103 LYS C CG 1 ATOM 7358 C CD . LYS C 3 103 ? -51.355 60.961 -15.327 1.00 184.01 ? 103 LYS C CD 1 ATOM 7359 C CE . LYS C 3 103 ? -52.818 60.789 -14.951 1.00 183.53 ? 103 LYS C CE 1 ATOM 7360 N NZ . LYS C 3 103 ? -53.440 62.086 -14.567 1.00 180.20 ? 103 LYS C NZ 1 ATOM 7361 N N . VAL C 3 104 ? -46.101 58.685 -16.506 1.00 182.27 ? 104 VAL C N 1 ATOM 7362 C CA . VAL C 3 104 ? -44.694 59.048 -16.402 1.00 180.04 ? 104 VAL C CA 1 ATOM 7363 C C . VAL C 3 104 ? -44.381 60.185 -17.363 1.00 179.07 ? 104 VAL C C 1 ATOM 7364 O O . VAL C 3 104 ? -44.479 60.023 -18.578 1.00 176.01 ? 104 VAL C O 1 ATOM 7365 C CB . VAL C 3 104 ? -43.768 57.856 -16.707 1.00 174.73 ? 104 VAL C CB 1 ATOM 7366 C CG1 . VAL C 3 104 ? -42.316 58.307 -16.746 1.00 172.47 ? 104 VAL C CG1 1 ATOM 7367 C CG2 . VAL C 3 104 ? -43.959 56.760 -15.674 1.00 175.48 ? 104 VAL C CG2 1 ATOM 7368 N N . GLU C 3 105 ? -44.013 61.337 -16.811 1.00 182.09 ? 105 GLU C N 1 ATOM 7369 C CA . GLU C 3 105 ? -43.713 62.517 -17.613 1.00 181.21 ? 105 GLU C CA 1 ATOM 7370 C C . GLU C 3 105 ? -42.240 62.894 -17.493 1.00 179.18 ? 105 GLU C C 1 ATOM 7371 O O . GLU C 3 105 ? -41.781 63.293 -16.424 1.00 172.62 ? 105 GLU C O 1 ATOM 7372 C CB . GLU C 3 105 ? -44.600 63.689 -17.186 1.00 181.78 ? 105 GLU C CB 1 ATOM 7373 C CG . GLU C 3 105 ? -46.090 63.380 -17.235 1.00 185.19 ? 105 GLU C CG 1 ATOM 7374 C CD . GLU C 3 105 ? -46.944 64.517 -16.710 1.00 191.40 ? 105 GLU C CD 1 ATOM 7375 O OE1 . GLU C 3 105 ? -46.384 65.458 -16.109 1.00 188.06 ? 105 GLU C OE1 1 ATOM 7376 O OE2 . GLU C 3 105 ? -48.178 64.469 -16.898 1.00 190.91 ? 105 GLU C OE2 1 ATOM 7377 N N . ILE C 3 106 ? -41.506 62.764 -18.595 1.00 179.90 ? 106 ILE C N 1 ATOM 7378 C CA . ILE C 3 106 ? -40.072 63.037 -18.605 1.00 172.55 ? 106 ILE C CA 1 ATOM 7379 C C . ILE C 3 106 ? -39.767 64.478 -18.202 1.00 168.10 ? 106 ILE C C 1 ATOM 7380 O O . ILE C 3 106 ? -40.355 65.420 -18.733 1.00 160.84 ? 106 ILE C O 1 ATOM 7381 C CB . ILE C 3 106 ? -39.450 62.751 -19.987 1.00 168.81 ? 106 ILE C CB 1 ATOM 7382 C CG1 . ILE C 3 106 ? -39.885 61.375 -20.497 1.00 165.51 ? 106 ILE C CG1 1 ATOM 7383 C CG2 . ILE C 3 106 ? -37.932 62.849 -19.922 1.00 166.54 ? 106 ILE C CG2 1 ATOM 7384 C CD1 . ILE C 3 106 ? -39.484 60.230 -19.594 1.00 161.57 ? 106 ILE C CD1 1 ATOM 7385 N N . LYS C 3 107 ? -38.848 64.638 -17.255 1.00 168.39 ? 107 LYS C N 1 ATOM 7386 C CA . LYS C 3 107 ? -38.477 65.959 -16.762 1.00 167.81 ? 107 LYS C CA 1 ATOM 7387 C C . LYS C 3 107 ? -37.075 66.339 -17.224 1.00 168.60 ? 107 LYS C C 1 ATOM 7388 O O . LYS C 3 107 ? -36.336 65.505 -17.747 1.00 168.22 ? 107 LYS C O 1 ATOM 7389 C CB . LYS C 3 107 ? -38.558 65.998 -15.235 1.00 166.75 ? 107 LYS C CB 1 ATOM 7390 C CG . LYS C 3 107 ? -38.413 67.387 -14.634 1.00 163.03 ? 107 LYS C CG 1 ATOM 7391 C CD . LYS C 3 107 ? -38.617 67.352 -13.128 1.00 168.22 ? 107 LYS C CD 1 ATOM 7392 C CE . LYS C 3 107 ? -38.682 68.753 -12.539 1.00 171.48 ? 107 LYS C CE 1 ATOM 7393 N NZ . LYS C 3 107 ? -38.947 68.727 -11.073 1.00 173.02 ? 107 LYS C NZ 1 ATOM 7394 N N . ARG C 3 108 ? -36.818 67.646 -16.950 1.00 216.47 ? 108 ARG C N 1 ATOM 7395 C CA . ARG C 3 108 ? -35.564 68.429 -16.995 1.00 230.56 ? 108 ARG C CA 1 ATOM 7396 C C . ARG C 3 108 ? -35.585 69.591 -15.930 1.00 243.77 ? 108 ARG C C 1 ATOM 7397 O O . ARG C 3 108 ? -35.736 69.314 -14.740 1.00 242.74 ? 108 ARG C O 1 ATOM 7398 C CB . ARG C 3 108 ? -35.327 68.992 -18.395 1.00 228.40 ? 108 ARG C CB 1 ATOM 7399 C CG . ARG C 3 108 ? -34.290 68.230 -19.204 1.00 229.52 ? 108 ARG C CG 1 ATOM 7400 C CD . ARG C 3 108 ? -34.467 68.469 -20.695 1.00 225.82 ? 108 ARG C CD 1 ATOM 7401 N NE . ARG C 3 108 ? -33.313 69.142 -21.282 1.00 215.33 ? 108 ARG C NE 1 ATOM 7402 C CZ . ARG C 3 108 ? -33.381 69.988 -22.305 1.00 211.43 ? 108 ARG C CZ 1 ATOM 7403 N NH1 . ARG C 3 108 ? -32.278 70.554 -22.775 1.00 189.19 ? 108 ARG C NH1 1 ATOM 7404 N NH2 . ARG C 3 108 ? -34.553 70.269 -22.858 1.00 212.13 ? 108 ARG C NH2 1 ATOM 7405 N N . THR C 3 109 ? -35.439 70.865 -16.345 1.00 245.32 ? 109 THR C N 1 ATOM 7406 C CA . THR C 3 109 ? -35.474 72.022 -15.458 1.00 228.27 ? 109 THR C CA 1 ATOM 7407 C C . THR C 3 109 ? -36.898 72.268 -14.960 1.00 209.66 ? 109 THR C C 1 ATOM 7408 O O . THR C 3 109 ? -37.672 71.325 -14.790 1.00 200.22 ? 109 THR C O 1 ATOM 7409 C CB . THR C 3 109 ? -34.934 73.284 -16.158 1.00 208.31 ? 109 THR C CB 1 ATOM 7410 O OG1 . THR C 3 109 ? -35.281 73.249 -17.548 1.00 196.97 ? 109 THR C OG1 1 ATOM 7411 C CG2 . THR C 3 109 ? -33.422 73.366 -16.018 1.00 186.66 ? 109 THR C CG2 1 ATOM 7412 N N . VAL C 3 110 ? -37.243 73.531 -14.726 1.00 200.99 ? 110 VAL C N 1 ATOM 7413 C CA . VAL C 3 110 ? -38.576 73.876 -14.242 1.00 203.93 ? 110 VAL C CA 1 ATOM 7414 C C . VAL C 3 110 ? -38.964 75.312 -14.586 1.00 194.09 ? 110 VAL C C 1 ATOM 7415 O O . VAL C 3 110 ? -38.280 76.261 -14.202 1.00 176.76 ? 110 VAL C O 1 ATOM 7416 C CB . VAL C 3 110 ? -38.691 73.677 -12.719 1.00 208.76 ? 110 VAL C CB 1 ATOM 7417 C CG1 . VAL C 3 110 ? -40.146 73.749 -12.283 1.00 214.89 ? 110 VAL C CG1 1 ATOM 7418 C CG2 . VAL C 3 110 ? -38.070 72.351 -12.309 1.00 193.50 ? 110 VAL C CG2 1 ATOM 7419 N N . ALA C 3 111 ? -40.070 75.461 -15.308 1.00 201.51 ? 111 ALA C N 1 ATOM 7420 C CA . ALA C 3 111 ? -40.594 76.777 -15.661 1.00 198.06 ? 111 ALA C CA 1 ATOM 7421 C C . ALA C 3 111 ? -41.855 77.137 -14.876 1.00 208.66 ? 111 ALA C C 1 ATOM 7422 O O . ALA C 3 111 ? -42.307 76.377 -14.019 1.00 208.54 ? 111 ALA C O 1 ATOM 7423 C CB . ALA C 3 111 ? -40.859 76.855 -17.158 1.00 193.05 ? 111 ALA C CB 1 ATOM 7424 N N . ALA C 3 112 ? -42.413 78.305 -15.180 1.00 209.64 ? 112 ALA C N 1 ATOM 7425 C CA . ALA C 3 112 ? -43.621 78.793 -14.524 1.00 211.84 ? 112 ALA C CA 1 ATOM 7426 C C . ALA C 3 112 ? -44.573 79.389 -15.560 1.00 212.30 ? 112 ALA C C 1 ATOM 7427 O O . ALA C 3 112 ? -44.128 79.882 -16.596 1.00 209.54 ? 112 ALA C O 1 ATOM 7428 C CB . ALA C 3 112 ? -43.262 79.829 -13.467 1.00 207.69 ? 112 ALA C CB 1 ATOM 7429 N N . PRO C 3 113 ? -45.888 79.341 -15.290 1.00 227.35 ? 113 PRO C N 1 ATOM 7430 C CA . PRO C 3 113 ? -46.864 79.849 -16.262 1.00 233.08 ? 113 PRO C CA 1 ATOM 7431 C C . PRO C 3 113 ? -46.789 81.360 -16.463 1.00 232.31 ? 113 PRO C C 1 ATOM 7432 O O . PRO C 3 113 ? -46.716 82.113 -15.492 1.00 225.56 ? 113 PRO C O 1 ATOM 7433 C CB . PRO C 3 113 ? -48.211 79.470 -15.636 1.00 233.97 ? 113 PRO C CB 1 ATOM 7434 C CG . PRO C 3 113 ? -47.934 79.360 -14.179 1.00 232.28 ? 113 PRO C CG 1 ATOM 7435 C CD . PRO C 3 113 ? -46.544 78.807 -14.083 1.00 235.33 ? 113 PRO C CD 1 ATOM 7436 N N . SER C 3 114 ? -46.806 81.788 -17.721 1.00 241.73 ? 114 SER C N 1 ATOM 7437 C CA . SER C 3 114 ? -46.875 83.205 -18.053 1.00 254.51 ? 114 SER C CA 1 ATOM 7438 C C . SER C 3 114 ? -48.326 83.575 -18.337 1.00 259.25 ? 114 SER C C 1 ATOM 7439 O O . SER C 3 114 ? -48.934 83.059 -19.275 1.00 254.66 ? 114 SER C O 1 ATOM 7440 C CB . SER C 3 114 ? -45.998 83.520 -19.265 1.00 253.50 ? 114 SER C CB 1 ATOM 7441 O OG . SER C 3 114 ? -44.646 83.175 -19.021 1.00 233.61 ? 114 SER C OG 1 ATOM 7442 N N . VAL C 3 115 ? -48.876 84.470 -17.524 1.00 268.22 ? 115 VAL C N 1 ATOM 7443 C CA . VAL C 3 115 ? -50.303 84.769 -17.573 1.00 273.53 ? 115 VAL C CA 1 ATOM 7444 C C . VAL C 3 115 ? -50.649 85.958 -18.468 1.00 274.30 ? 115 VAL C C 1 ATOM 7445 O O . VAL C 3 115 ? -50.168 87.071 -18.257 1.00 274.71 ? 115 VAL C O 1 ATOM 7446 C CB . VAL C 3 115 ? -50.864 85.025 -16.161 1.00 265.01 ? 115 VAL C CB 1 ATOM 7447 C CG1 . VAL C 3 115 ? -52.379 85.140 -16.206 1.00 258.47 ? 115 VAL C CG1 1 ATOM 7448 C CG2 . VAL C 3 115 ? -50.440 83.912 -15.216 1.00 256.96 ? 115 VAL C CG2 1 ATOM 7449 N N . PHE C 3 116 ? -51.489 85.706 -19.467 1.00 280.07 ? 116 PHE C N 1 ATOM 7450 C CA . PHE C 3 116 ? -52.011 86.758 -20.332 1.00 279.05 ? 116 PHE C CA 1 ATOM 7451 C C . PHE C 3 116 ? -53.520 86.599 -20.497 1.00 276.67 ? 116 PHE C C 1 ATOM 7452 O O . PHE C 3 116 ? -54.039 85.484 -20.472 1.00 272.64 ? 116 PHE C O 1 ATOM 7453 C CB . PHE C 3 116 ? -51.330 86.726 -21.703 1.00 277.33 ? 116 PHE C CB 1 ATOM 7454 C CG . PHE C 3 116 ? -49.904 87.199 -21.685 1.00 258.41 ? 116 PHE C CG 1 ATOM 7455 C CD1 . PHE C 3 116 ? -49.606 88.547 -21.800 1.00 237.45 ? 116 PHE C CD1 1 ATOM 7456 C CD2 . PHE C 3 116 ? -48.861 86.296 -21.560 1.00 255.44 ? 116 PHE C CD2 1 ATOM 7457 C CE1 . PHE C 3 116 ? -48.295 88.985 -21.786 1.00 228.37 ? 116 PHE C CE1 1 ATOM 7458 C CE2 . PHE C 3 116 ? -47.548 86.728 -21.546 1.00 250.12 ? 116 PHE C CE2 1 ATOM 7459 C CZ . PHE C 3 116 ? -47.264 88.075 -21.659 1.00 240.72 ? 116 PHE C CZ 1 ATOM 7460 N N . ILE C 3 117 ? -54.219 87.717 -20.664 1.00 283.69 ? 117 ILE C N 1 ATOM 7461 C CA . ILE C 3 117 ? -55.667 87.695 -20.844 1.00 291.31 ? 117 ILE C CA 1 ATOM 7462 C C . ILE C 3 117 ? -56.040 88.308 -22.196 1.00 298.90 ? 117 ILE C C 1 ATOM 7463 O O . ILE C 3 117 ? -55.279 89.099 -22.754 1.00 292.73 ? 117 ILE C O 1 ATOM 7464 C CB . ILE C 3 117 ? -56.391 88.420 -19.684 1.00 283.40 ? 117 ILE C CB 1 ATOM 7465 C CG1 . ILE C 3 117 ? -57.832 87.920 -19.545 1.00 267.39 ? 117 ILE C CG1 1 ATOM 7466 C CG2 . ILE C 3 117 ? -56.329 89.933 -19.862 1.00 280.05 ? 117 ILE C CG2 1 ATOM 7467 C CD1 . ILE C 3 117 ? -58.537 88.426 -18.307 1.00 233.81 ? 117 ILE C CD1 1 ATOM 7468 N N . PHE C 3 118 ? -57.202 87.935 -22.728 1.00 302.93 ? 118 PHE C N 1 ATOM 7469 C CA . PHE C 3 118 ? -57.587 88.350 -24.077 1.00 297.40 ? 118 PHE C CA 1 ATOM 7470 C C . PHE C 3 118 ? -58.997 88.942 -24.149 1.00 301.87 ? 118 PHE C C 1 ATOM 7471 O O . PHE C 3 118 ? -59.955 88.235 -24.460 1.00 300.22 ? 118 PHE C O 1 ATOM 7472 C CB . PHE C 3 118 ? -57.462 87.169 -25.043 1.00 281.73 ? 118 PHE C CB 1 ATOM 7473 C CG . PHE C 3 118 ? -56.102 86.527 -25.042 1.00 282.14 ? 118 PHE C CG 1 ATOM 7474 C CD1 . PHE C 3 118 ? -55.102 86.992 -25.879 1.00 275.06 ? 118 PHE C CD1 1 ATOM 7475 C CD2 . PHE C 3 118 ? -55.823 85.460 -24.201 1.00 282.19 ? 118 PHE C CD2 1 ATOM 7476 C CE1 . PHE C 3 118 ? -53.851 86.405 -25.881 1.00 260.36 ? 118 PHE C CE1 1 ATOM 7477 C CE2 . PHE C 3 118 ? -54.572 84.869 -24.198 1.00 263.19 ? 118 PHE C CE2 1 ATOM 7478 C CZ . PHE C 3 118 ? -53.586 85.343 -25.039 1.00 247.95 ? 118 PHE C CZ 1 ATOM 7479 N N . PRO C 3 119 ? -59.120 90.248 -23.859 1.00 309.52 ? 119 PRO C N 1 ATOM 7480 C CA . PRO C 3 119 ? -60.382 91.005 -23.829 1.00 307.88 ? 119 PRO C CA 1 ATOM 7481 C C . PRO C 3 119 ? -61.201 91.186 -25.130 1.00 308.49 ? 119 PRO C C 1 ATOM 7482 O O . PRO C 3 119 ? -62.418 91.013 -25.057 1.00 294.93 ? 119 PRO C O 1 ATOM 7483 C CB . PRO C 3 119 ? -59.949 92.381 -23.300 1.00 295.09 ? 119 PRO C CB 1 ATOM 7484 C CG . PRO C 3 119 ? -58.674 92.130 -22.580 1.00 288.96 ? 119 PRO C CG 1 ATOM 7485 C CD . PRO C 3 119 ? -57.992 91.052 -23.358 1.00 296.84 ? 119 PRO C CD 1 ATOM 7486 N N . PRO C 3 120 ? -60.572 91.528 -26.277 1.00 312.95 ? 120 PRO C N 1 ATOM 7487 C CA . PRO C 3 120 ? -61.394 92.099 -27.360 1.00 309.56 ? 120 PRO C CA 1 ATOM 7488 C C . PRO C 3 120 ? -62.491 91.196 -27.935 1.00 303.13 ? 120 PRO C C 1 ATOM 7489 O O . PRO C 3 120 ? -62.230 90.074 -28.371 1.00 299.94 ? 120 PRO C O 1 ATOM 7490 C CB . PRO C 3 120 ? -60.363 92.406 -28.457 1.00 281.54 ? 120 PRO C CB 1 ATOM 7491 C CG . PRO C 3 120 ? -59.050 92.461 -27.752 1.00 260.54 ? 120 PRO C CG 1 ATOM 7492 C CD . PRO C 3 120 ? -59.155 91.444 -26.667 1.00 286.52 ? 120 PRO C CD 1 ATOM 7493 N N . SER C 3 121 ? -63.716 91.718 -27.928 1.00 298.15 ? 121 SER C N 1 ATOM 7494 C CA . SER C 3 121 ? -64.884 91.070 -28.528 1.00 293.66 ? 121 SER C CA 1 ATOM 7495 C C . SER C 3 121 ? -65.306 91.628 -29.898 1.00 294.06 ? 121 SER C C 1 ATOM 7496 O O . SER C 3 121 ? -66.345 91.238 -30.423 1.00 296.89 ? 121 SER C O 1 ATOM 7497 C CB . SER C 3 121 ? -66.070 91.093 -27.565 1.00 290.67 ? 121 SER C CB 1 ATOM 7498 O OG . SER C 3 121 ? -67.146 90.314 -28.065 1.00 284.76 ? 121 SER C OG 1 ATOM 7499 N N . ASP C 3 122 ? -64.524 92.551 -30.453 1.00 292.55 ? 122 ASP C N 1 ATOM 7500 C CA . ASP C 3 122 ? -64.976 93.427 -31.548 1.00 284.52 ? 122 ASP C CA 1 ATOM 7501 C C . ASP C 3 122 ? -65.725 92.791 -32.735 1.00 282.06 ? 122 ASP C C 1 ATOM 7502 O O . ASP C 3 122 ? -66.797 93.268 -33.111 1.00 275.21 ? 122 ASP C O 1 ATOM 7503 C CB . ASP C 3 122 ? -63.808 94.269 -32.068 1.00 270.99 ? 122 ASP C CB 1 ATOM 7504 C CG . ASP C 3 122 ? -63.305 95.264 -31.041 1.00 257.38 ? 122 ASP C CG 1 ATOM 7505 O OD1 . ASP C 3 122 ? -64.086 95.638 -30.140 1.00 265.73 ? 122 ASP C OD1 1 ATOM 7506 O OD2 . ASP C 3 122 ? -62.130 95.675 -31.138 1.00 234.63 ? 122 ASP C OD2 1 ATOM 7507 N N . GLU C 3 123 ? -65.177 91.731 -33.323 1.00 288.24 ? 123 GLU C N 1 ATOM 7508 C CA . GLU C 3 123 ? -65.833 91.076 -34.459 1.00 278.24 ? 123 GLU C CA 1 ATOM 7509 C C . GLU C 3 123 ? -66.896 90.090 -33.984 1.00 278.28 ? 123 GLU C C 1 ATOM 7510 O O . GLU C 3 123 ? -67.587 89.457 -34.783 1.00 259.89 ? 123 GLU C O 1 ATOM 7511 C CB . GLU C 3 123 ? -64.814 90.359 -35.350 1.00 260.73 ? 123 GLU C CB 1 ATOM 7512 C CG . GLU C 3 123 ? -63.847 91.278 -36.081 1.00 244.35 ? 123 GLU C CG 1 ATOM 7513 C CD . GLU C 3 123 ? -62.709 91.757 -35.200 1.00 241.79 ? 123 GLU C CD 1 ATOM 7514 O OE1 . GLU C 3 123 ? -61.898 92.579 -35.675 1.00 229.39 ? 123 GLU C OE1 1 ATOM 7515 O OE2 . GLU C 3 123 ? -62.623 91.311 -34.037 1.00 256.30 ? 123 GLU C OE2 1 ATOM 7516 N N . GLN C 3 124 ? -67.015 89.983 -32.667 1.00 289.96 ? 124 GLN C N 1 ATOM 7517 C CA . GLN C 3 124 ? -67.922 89.052 -32.009 1.00 280.76 ? 124 GLN C CA 1 ATOM 7518 C C . GLN C 3 124 ? -69.163 89.781 -31.500 1.00 285.29 ? 124 GLN C C 1 ATOM 7519 O O . GLN C 3 124 ? -70.284 89.396 -31.814 1.00 283.55 ? 124 GLN C O 1 ATOM 7520 C CB . GLN C 3 124 ? -67.216 88.303 -30.879 1.00 275.95 ? 124 GLN C CB 1 ATOM 7521 C CG . GLN C 3 124 ? -68.003 87.131 -30.326 1.00 267.10 ? 124 GLN C CG 1 ATOM 7522 C CD . GLN C 3 124 ? -67.201 86.309 -29.339 1.00 269.51 ? 124 GLN C CD 1 ATOM 7523 O OE1 . GLN C 3 124 ? -66.014 86.559 -29.126 1.00 272.35 ? 124 GLN C OE1 1 ATOM 7524 N NE2 . GLN C 3 124 ? -67.845 85.320 -28.731 1.00 269.39 ? 124 GLN C NE2 1 ATOM 7525 N N . LEU C 3 125 ? -68.939 90.814 -30.691 1.00 291.11 ? 125 LEU C N 1 ATOM 7526 C CA . LEU C 3 125 ? -69.988 91.524 -29.954 1.00 289.80 ? 125 LEU C CA 1 ATOM 7527 C C . LEU C 3 125 ? -71.261 91.815 -30.760 1.00 281.04 ? 125 LEU C C 1 ATOM 7528 O O . LEU C 3 125 ? -72.367 91.732 -30.223 1.00 272.85 ? 125 LEU C O 1 ATOM 7529 C CB . LEU C 3 125 ? -69.421 92.837 -29.403 1.00 280.00 ? 125 LEU C CB 1 ATOM 7530 C CG . LEU C 3 125 ? -70.340 93.749 -28.589 1.00 262.02 ? 125 LEU C CG 1 ATOM 7531 C CD1 . LEU C 3 125 ? -70.724 93.090 -27.274 1.00 255.25 ? 125 LEU C CD1 1 ATOM 7532 C CD2 . LEU C 3 125 ? -69.676 95.097 -28.346 1.00 239.04 ? 125 LEU C CD2 1 ATOM 7533 N N . LYS C 3 126 ? -71.114 92.155 -32.037 1.00 275.75 ? 126 LYS C N 1 ATOM 7534 C CA . LYS C 3 126 ? -72.281 92.369 -32.893 1.00 261.24 ? 126 LYS C CA 1 ATOM 7535 C C . LYS C 3 126 ? -72.924 91.065 -33.379 1.00 256.78 ? 126 LYS C C 1 ATOM 7536 O O . LYS C 3 126 ? -74.026 91.082 -33.927 1.00 252.38 ? 126 LYS C O 1 ATOM 7537 C CB . LYS C 3 126 ? -71.937 93.264 -34.087 1.00 242.01 ? 126 LYS C CB 1 ATOM 7538 C CG . LYS C 3 126 ? -72.014 94.755 -33.797 1.00 222.27 ? 126 LYS C CG 1 ATOM 7539 C CD . LYS C 3 126 ? -70.711 95.282 -33.227 1.00 216.73 ? 126 LYS C CD 1 ATOM 7540 C CE . LYS C 3 126 ? -69.591 95.190 -34.251 1.00 203.63 ? 126 LYS C CE 1 ATOM 7541 N NZ . LYS C 3 126 ? -68.317 95.763 -33.738 1.00 194.85 ? 126 LYS C NZ 1 ATOM 7542 N N . SER C 3 127 ? -72.240 89.942 -33.180 1.00 258.62 ? 127 SER C N 1 ATOM 7543 C CA . SER C 3 127 ? -72.779 88.645 -33.588 1.00 246.86 ? 127 SER C CA 1 ATOM 7544 C C . SER C 3 127 ? -73.619 88.020 -32.477 1.00 241.97 ? 127 SER C C 1 ATOM 7545 O O . SER C 3 127 ? -74.266 86.994 -32.680 1.00 217.96 ? 127 SER C O 1 ATOM 7546 C CB . SER C 3 127 ? -71.658 87.688 -34.002 1.00 243.07 ? 127 SER C CB 1 ATOM 7547 O OG . SER C 3 127 ? -70.792 87.417 -32.913 1.00 258.90 ? 127 SER C OG 1 ATOM 7548 N N . GLY C 3 128 ? -73.605 88.648 -31.305 1.00 245.54 ? 128 GLY C N 1 ATOM 7549 C CA . GLY C 3 128 ? -74.442 88.214 -30.203 1.00 235.31 ? 128 GLY C CA 1 ATOM 7550 C C . GLY C 3 128 ? -73.733 87.504 -29.064 1.00 237.47 ? 128 GLY C C 1 ATOM 7551 O O . GLY C 3 128 ? -74.377 87.081 -28.105 1.00 229.21 ? 128 GLY C O 1 ATOM 7552 N N . THR C 3 129 ? -72.413 87.367 -29.156 1.00 257.62 ? 129 THR C N 1 ATOM 7553 C CA . THR C 3 129 ? -71.651 86.743 -28.076 1.00 267.16 ? 129 THR C CA 1 ATOM 7554 C C . THR C 3 129 ? -70.406 87.545 -27.701 1.00 274.89 ? 129 THR C C 1 ATOM 7555 O O . THR C 3 129 ? -70.091 88.556 -28.328 1.00 281.43 ? 129 THR C O 1 ATOM 7556 C CB . THR C 3 129 ? -71.229 85.300 -28.436 1.00 261.26 ? 129 THR C CB 1 ATOM 7557 O OG1 . THR C 3 129 ? -70.568 85.294 -29.707 1.00 260.62 ? 129 THR C OG1 1 ATOM 7558 C CG2 . THR C 3 129 ? -72.441 84.381 -28.498 1.00 245.45 ? 129 THR C CG2 1 ATOM 7559 N N . ALA C 3 130 ? -69.707 87.086 -26.666 1.00 268.72 ? 130 ALA C N 1 ATOM 7560 C CA . ALA C 3 130 ? -68.455 87.700 -26.236 1.00 261.98 ? 130 ALA C CA 1 ATOM 7561 C C . ALA C 3 130 ? -67.504 86.639 -25.690 1.00 275.14 ? 130 ALA C C 1 ATOM 7562 O O . ALA C 3 130 ? -67.920 85.762 -24.933 1.00 274.10 ? 130 ALA C O 1 ATOM 7563 C CB . ALA C 3 130 ? -68.720 88.771 -25.190 1.00 218.20 ? 130 ALA C CB 1 ATOM 7564 N N . SER C 3 131 ? -66.232 86.717 -26.067 1.00 285.92 ? 131 SER C N 1 ATOM 7565 C CA . SER C 3 131 ? -65.249 85.752 -25.583 1.00 277.07 ? 131 SER C CA 1 ATOM 7566 C C . SER C 3 131 ? -63.997 86.411 -25.007 1.00 274.82 ? 131 SER C C 1 ATOM 7567 O O . SER C 3 131 ? -63.229 87.047 -25.729 1.00 265.70 ? 131 SER C O 1 ATOM 7568 C CB . SER C 3 131 ? -64.861 84.778 -26.699 1.00 262.63 ? 131 SER C CB 1 ATOM 7569 O OG . SER C 3 131 ? -66.000 84.101 -27.202 1.00 266.13 ? 131 SER C OG 1 ATOM 7570 N N . VAL C 3 132 ? -63.801 86.252 -23.702 1.00 280.67 ? 132 VAL C N 1 ATOM 7571 C CA . VAL C 3 132 ? -62.574 86.690 -23.047 1.00 288.67 ? 132 VAL C CA 1 ATOM 7572 C C . VAL C 3 132 ? -61.917 85.500 -22.357 1.00 293.74 ? 132 VAL C C 1 ATOM 7573 O O . VAL C 3 132 ? -62.439 84.987 -21.369 1.00 296.72 ? 132 VAL C O 1 ATOM 7574 C CB . VAL C 3 132 ? -62.853 87.786 -22.001 1.00 281.79 ? 132 VAL C CB 1 ATOM 7575 C CG1 . VAL C 3 132 ? -61.564 88.203 -21.311 1.00 281.74 ? 132 VAL C CG1 1 ATOM 7576 C CG2 . VAL C 3 132 ? -63.529 88.984 -22.652 1.00 269.59 ? 132 VAL C CG2 1 ATOM 7577 N N . VAL C 3 133 ? -60.772 85.062 -22.870 1.00 296.13 ? 133 VAL C N 1 ATOM 7578 C CA . VAL C 3 133 ? -60.117 83.873 -22.331 1.00 294.58 ? 133 VAL C CA 1 ATOM 7579 C C . VAL C 3 133 ? -58.873 84.181 -21.501 1.00 292.53 ? 133 VAL C C 1 ATOM 7580 O O . VAL C 3 133 ? -58.465 85.335 -21.371 1.00 290.26 ? 133 VAL C O 1 ATOM 7581 C CB . VAL C 3 133 ? -59.744 82.881 -23.451 1.00 290.83 ? 133 VAL C CB 1 ATOM 7582 C CG1 . VAL C 3 133 ? -60.998 82.321 -24.103 1.00 280.93 ? 133 VAL C CG1 1 ATOM 7583 C CG2 . VAL C 3 133 ? -58.855 83.555 -24.484 1.00 286.42 ? 133 VAL C CG2 1 ATOM 7584 N N . CYS C 3 134 ? -58.278 83.130 -20.946 1.00 293.37 ? 134 CYS C N 1 ATOM 7585 C CA . CYS C 3 134 ? -57.038 83.237 -20.187 1.00 295.78 ? 134 CYS C CA 1 ATOM 7586 C C . CYS C 3 134 ? -56.140 82.050 -20.519 1.00 290.19 ? 134 CYS C C 1 ATOM 7587 O O . CYS C 3 134 ? -56.571 80.900 -20.443 1.00 295.43 ? 134 CYS C O 1 ATOM 7588 C CB . CYS C 3 134 ? -57.328 83.281 -18.686 1.00 292.27 ? 134 CYS C CB 1 ATOM 7589 S SG . CYS C 3 134 ? -55.869 83.499 -17.641 1.00 303.19 ? 134 CYS C SG 1 ATOM 7590 N N . LEU C 3 135 ? -54.893 82.328 -20.887 1.00 274.88 ? 135 LEU C N 1 ATOM 7591 C CA . LEU C 3 135 ? -53.982 81.274 -21.321 1.00 260.68 ? 135 LEU C CA 1 ATOM 7592 C C . LEU C 3 135 ? -52.771 81.109 -20.409 1.00 267.16 ? 135 LEU C C 1 ATOM 7593 O O . LEU C 3 135 ? -52.073 82.074 -20.101 1.00 276.58 ? 135 LEU C O 1 ATOM 7594 C CB . LEU C 3 135 ? -53.510 81.530 -22.754 1.00 244.86 ? 135 LEU C CB 1 ATOM 7595 C CG . LEU C 3 135 ? -52.430 80.582 -23.281 1.00 223.45 ? 135 LEU C CG 1 ATOM 7596 C CD1 . LEU C 3 135 ? -53.006 79.205 -23.575 1.00 223.75 ? 135 LEU C CD1 1 ATOM 7597 C CD2 . LEU C 3 135 ? -51.750 81.164 -24.510 1.00 209.72 ? 135 LEU C CD2 1 ATOM 7598 N N . LEU C 3 136 ? -52.531 79.872 -19.985 1.00 264.78 ? 136 LEU C N 1 ATOM 7599 C CA . LEU C 3 136 ? -51.314 79.523 -19.266 1.00 255.72 ? 136 LEU C CA 1 ATOM 7600 C C . LEU C 3 136 ? -50.422 78.713 -20.195 1.00 250.82 ? 136 LEU C C 1 ATOM 7601 O O . LEU C 3 136 ? -50.745 77.577 -20.536 1.00 256.29 ? 136 LEU C O 1 ATOM 7602 C CB . LEU C 3 136 ? -51.644 78.706 -18.016 1.00 243.33 ? 136 LEU C CB 1 ATOM 7603 C CG . LEU C 3 136 ? -52.449 79.417 -16.929 1.00 220.21 ? 136 LEU C CG 1 ATOM 7604 C CD1 . LEU C 3 136 ? -52.764 78.463 -15.788 1.00 198.76 ? 136 LEU C CD1 1 ATOM 7605 C CD2 . LEU C 3 136 ? -51.687 80.628 -16.424 1.00 225.13 ? 136 LEU C CD2 1 ATOM 7606 N N . ASN C 3 137 ? -49.302 79.299 -20.605 1.00 237.50 ? 137 ASN C N 1 ATOM 7607 C CA . ASN C 3 137 ? -48.426 78.663 -21.585 1.00 227.12 ? 137 ASN C CA 1 ATOM 7608 C C . ASN C 3 137 ? -47.029 78.359 -21.048 1.00 228.54 ? 137 ASN C C 1 ATOM 7609 O O . ASN C 3 137 ? -46.446 79.163 -20.320 1.00 231.59 ? 137 ASN C O 1 ATOM 7610 C CB . ASN C 3 137 ? -48.331 79.523 -22.848 1.00 212.13 ? 137 ASN C CB 1 ATOM 7611 C CG . ASN C 3 137 ? -47.403 78.929 -23.890 1.00 206.82 ? 137 ASN C CG 1 ATOM 7612 O OD1 . ASN C 3 137 ? -47.804 78.078 -24.684 1.00 186.39 ? 137 ASN C OD1 1 ATOM 7613 N ND2 . ASN C 3 137 ? -46.154 79.378 -23.892 1.00 230.23 ? 137 ASN C ND2 1 ATOM 7614 N N . ASN C 3 138 ? -46.506 77.193 -21.420 1.00 228.77 ? 138 ASN C N 1 ATOM 7615 C CA . ASN C 3 138 ? -45.165 76.763 -21.026 1.00 229.57 ? 138 ASN C CA 1 ATOM 7616 C C . ASN C 3 138 ? -44.919 76.762 -19.518 1.00 237.89 ? 138 ASN C C 1 ATOM 7617 O O . ASN C 3 138 ? -44.167 77.589 -19.000 1.00 237.16 ? 138 ASN C O 1 ATOM 7618 C CB . ASN C 3 138 ? -44.087 77.566 -21.760 1.00 219.45 ? 138 ASN C CB 1 ATOM 7619 C CG . ASN C 3 138 ? -44.008 77.219 -23.234 1.00 212.48 ? 138 ASN C CG 1 ATOM 7620 O OD1 . ASN C 3 138 ? -44.036 78.098 -24.095 1.00 210.28 ? 138 ASN C OD1 1 ATOM 7621 N ND2 . ASN C 3 138 ? -43.918 75.928 -23.533 1.00 207.79 ? 138 ASN C ND2 1 ATOM 7622 N N . PHE C 3 139 ? -45.563 75.829 -18.823 1.00 243.08 ? 139 PHE C N 1 ATOM 7623 C CA . PHE C 3 139 ? -45.444 75.730 -17.373 1.00 237.91 ? 139 PHE C CA 1 ATOM 7624 C C . PHE C 3 139 ? -45.241 74.293 -16.905 1.00 239.24 ? 139 PHE C C 1 ATOM 7625 O O . PHE C 3 139 ? -45.710 73.347 -17.537 1.00 242.78 ? 139 PHE C O 1 ATOM 7626 C CB . PHE C 3 139 ? -46.681 76.318 -16.694 1.00 238.30 ? 139 PHE C CB 1 ATOM 7627 C CG . PHE C 3 139 ? -47.952 75.581 -17.004 1.00 238.11 ? 139 PHE C CG 1 ATOM 7628 C CD1 . PHE C 3 139 ? -48.663 75.857 -18.160 1.00 232.82 ? 139 PHE C CD1 1 ATOM 7629 C CD2 . PHE C 3 139 ? -48.442 74.617 -16.137 1.00 242.03 ? 139 PHE C CD2 1 ATOM 7630 C CE1 . PHE C 3 139 ? -49.832 75.182 -18.448 1.00 231.93 ? 139 PHE C CE1 1 ATOM 7631 C CE2 . PHE C 3 139 ? -49.611 73.938 -16.420 1.00 241.47 ? 139 PHE C CE2 1 ATOM 7632 C CZ . PHE C 3 139 ? -50.307 74.221 -17.576 1.00 229.35 ? 139 PHE C CZ 1 ATOM 7633 N N . TYR C 3 140 ? -44.535 74.144 -15.790 1.00 235.92 ? 140 TYR C N 1 ATOM 7634 C CA . TYR C 3 140 ? -44.335 72.844 -15.168 1.00 239.99 ? 140 TYR C CA 1 ATOM 7635 C C . TYR C 3 140 ? -44.352 73.040 -13.656 1.00 239.43 ? 140 TYR C C 1 ATOM 7636 O O . TYR C 3 140 ? -43.835 74.040 -13.159 1.00 230.31 ? 140 TYR C O 1 ATOM 7637 C CB . TYR C 3 140 ? -42.990 72.265 -15.612 1.00 232.30 ? 140 TYR C CB 1 ATOM 7638 C CG . TYR C 3 140 ? -42.864 70.766 -15.461 1.00 241.66 ? 140 TYR C CG 1 ATOM 7639 C CD1 . TYR C 3 140 ? -43.322 69.910 -16.453 1.00 243.44 ? 140 TYR C CD1 1 ATOM 7640 C CD2 . TYR C 3 140 ? -42.277 70.207 -14.332 1.00 234.84 ? 140 TYR C CD2 1 ATOM 7641 C CE1 . TYR C 3 140 ? -43.207 68.539 -16.323 1.00 235.61 ? 140 TYR C CE1 1 ATOM 7642 C CE2 . TYR C 3 140 ? -42.159 68.835 -14.194 1.00 229.63 ? 140 TYR C CE2 1 ATOM 7643 C CZ . TYR C 3 140 ? -42.626 68.006 -15.193 1.00 225.43 ? 140 TYR C CZ 1 ATOM 7644 O OH . TYR C 3 140 ? -42.511 66.642 -15.062 1.00 203.99 ? 140 TYR C OH 1 ATOM 7645 N N . PRO C 3 141 ? -44.935 72.087 -12.910 1.00 244.30 ? 141 PRO C N 1 ATOM 7646 C CA . PRO C 3 141 ? -45.632 70.871 -13.343 1.00 246.08 ? 141 PRO C CA 1 ATOM 7647 C C . PRO C 3 141 ? -47.075 71.126 -13.773 1.00 244.73 ? 141 PRO C C 1 ATOM 7648 O O . PRO C 3 141 ? -47.497 72.275 -13.915 1.00 243.54 ? 141 PRO C O 1 ATOM 7649 C CB . PRO C 3 141 ? -45.622 69.989 -12.085 1.00 240.46 ? 141 PRO C CB 1 ATOM 7650 C CG . PRO C 3 141 ? -44.682 70.657 -11.125 1.00 232.57 ? 141 PRO C CG 1 ATOM 7651 C CD . PRO C 3 141 ? -44.763 72.107 -11.451 1.00 237.35 ? 141 PRO C CD 1 ATOM 7652 N N . ARG C 3 142 ? -47.813 70.039 -13.975 1.00 246.19 ? 142 ARG C N 1 ATOM 7653 C CA . ARG C 3 142 ? -49.181 70.078 -14.488 1.00 248.43 ? 142 ARG C CA 1 ATOM 7654 C C . ARG C 3 142 ? -50.177 70.861 -13.626 1.00 246.86 ? 142 ARG C C 1 ATOM 7655 O O . ARG C 3 142 ? -51.149 71.408 -14.149 1.00 241.44 ? 142 ARG C O 1 ATOM 7656 C CB . ARG C 3 142 ? -49.689 68.646 -14.710 1.00 237.28 ? 142 ARG C CB 1 ATOM 7657 C CG . ARG C 3 142 ? -51.145 68.530 -15.144 1.00 213.72 ? 142 ARG C CG 1 ATOM 7658 C CD . ARG C 3 142 ? -51.411 69.258 -16.454 1.00 212.90 ? 142 ARG C CD 1 ATOM 7659 N NE . ARG C 3 142 ? -52.777 69.041 -16.919 1.00 215.43 ? 142 ARG C NE 1 ATOM 7660 C CZ . ARG C 3 142 ? -53.143 68.030 -17.699 1.00 228.26 ? 142 ARG C CZ 1 ATOM 7661 N NH1 . ARG C 3 142 ? -52.242 67.146 -18.104 1.00 226.38 ? 142 ARG C NH1 1 ATOM 7662 N NH2 . ARG C 3 142 ? -54.408 67.902 -18.075 1.00 237.00 ? 142 ARG C NH2 1 ATOM 7663 N N . GLU C 3 143 ? -49.933 70.956 -12.322 1.00 247.05 ? 143 GLU C N 1 ATOM 7664 C CA . GLU C 3 143 ? -50.983 71.461 -11.445 1.00 245.35 ? 143 GLU C CA 1 ATOM 7665 C C . GLU C 3 143 ? -51.132 72.972 -11.543 1.00 256.32 ? 143 GLU C C 1 ATOM 7666 O O . GLU C 3 143 ? -50.233 73.735 -11.189 1.00 253.20 ? 143 GLU C O 1 ATOM 7667 C CB . GLU C 3 143 ? -50.713 71.072 -9.986 1.00 216.48 ? 143 GLU C CB 1 ATOM 7668 C CG . GLU C 3 143 ? -51.047 69.630 -9.640 1.00 201.87 ? 143 GLU C CG 1 ATOM 7669 C CD . GLU C 3 143 ? -49.997 68.651 -10.123 1.00 213.83 ? 143 GLU C CD 1 ATOM 7670 O OE1 . GLU C 3 143 ? -48.924 69.102 -10.577 1.00 220.68 ? 143 GLU C OE1 1 ATOM 7671 O OE2 . GLU C 3 143 ? -50.243 67.428 -10.047 1.00 212.50 ? 143 GLU C OE2 1 ATOM 7672 N N . ALA C 3 144 ? -52.295 73.381 -12.033 1.00 262.63 ? 144 ALA C N 1 ATOM 7673 C CA . ALA C 3 144 ? -52.730 74.763 -11.997 1.00 264.63 ? 144 ALA C CA 1 ATOM 7674 C C . ALA C 3 144 ? -54.249 74.733 -11.952 1.00 268.87 ? 144 ALA C C 1 ATOM 7675 O O . ALA C 3 144 ? -54.877 73.933 -12.646 1.00 266.51 ? 144 ALA C O 1 ATOM 7676 C CB . ALA C 3 144 ? -52.239 75.511 -13.226 1.00 248.00 ? 144 ALA C CB 1 ATOM 7677 N N . LYS C 3 145 ? -54.845 75.605 -11.150 1.00 274.47 ? 145 LYS C N 1 ATOM 7678 C CA . LYS C 3 145 ? -56.297 75.670 -11.080 1.00 258.97 ? 145 LYS C CA 1 ATOM 7679 C C . LYS C 3 145 ? -56.757 77.100 -11.308 1.00 259.77 ? 145 LYS C C 1 ATOM 7680 O O . LYS C 3 145 ? -56.255 78.034 -10.682 1.00 261.98 ? 145 LYS C O 1 ATOM 7681 C CB . LYS C 3 145 ? -56.808 75.140 -9.739 1.00 239.23 ? 145 LYS C CB 1 ATOM 7682 C CG . LYS C 3 145 ? -58.306 74.878 -9.715 1.00 229.69 ? 145 LYS C CG 1 ATOM 7683 C CD . LYS C 3 145 ? -58.715 73.907 -10.812 1.00 218.76 ? 145 LYS C CD 1 ATOM 7684 C CE . LYS C 3 145 ? -60.222 73.695 -10.834 1.00 197.47 ? 145 LYS C CE 1 ATOM 7685 N NZ . LYS C 3 145 ? -60.633 72.745 -11.907 1.00 147.04 ? 145 LYS C NZ 1 ATOM 7686 N N . VAL C 3 146 ? -57.711 77.263 -12.215 1.00 260.05 ? 146 VAL C N 1 ATOM 7687 C CA . VAL C 3 146 ? -58.151 78.588 -12.620 1.00 263.99 ? 146 VAL C CA 1 ATOM 7688 C C . VAL C 3 146 ? -59.517 78.928 -12.040 1.00 272.66 ? 146 VAL C C 1 ATOM 7689 O O . VAL C 3 146 ? -60.501 78.230 -12.287 1.00 269.23 ? 146 VAL C O 1 ATOM 7690 C CB . VAL C 3 146 ? -58.203 78.711 -14.153 1.00 251.54 ? 146 VAL C CB 1 ATOM 7691 C CG1 . VAL C 3 146 ? -58.597 80.121 -14.556 1.00 254.93 ? 146 VAL C CG1 1 ATOM 7692 C CG2 . VAL C 3 146 ? -56.858 78.334 -14.757 1.00 248.74 ? 146 VAL C CG2 1 ATOM 7693 N N . GLN C 3 147 ? -59.567 80.005 -11.263 1.00 273.85 ? 147 GLN C N 1 ATOM 7694 C CA . GLN C 3 147 ? -60.824 80.503 -10.720 1.00 256.88 ? 147 GLN C CA 1 ATOM 7695 C C . GLN C 3 147 ? -61.086 81.913 -11.235 1.00 258.95 ? 147 GLN C C 1 ATOM 7696 O O . GLN C 3 147 ? -60.165 82.609 -11.662 1.00 264.84 ? 147 GLN C O 1 ATOM 7697 C CB . GLN C 3 147 ? -60.805 80.500 -9.189 1.00 244.28 ? 147 GLN C CB 1 ATOM 7698 C CG . GLN C 3 147 ? -60.660 79.125 -8.557 1.00 237.61 ? 147 GLN C CG 1 ATOM 7699 C CD . GLN C 3 147 ? -59.213 78.718 -8.366 1.00 249.98 ? 147 GLN C CD 1 ATOM 7700 O OE1 . GLN C 3 147 ? -58.295 79.479 -8.672 1.00 259.53 ? 147 GLN C OE1 1 ATOM 7701 N NE2 . GLN C 3 147 ? -59.003 77.512 -7.852 1.00 241.98 ? 147 GLN C NE2 1 ATOM 7702 N N . TRP C 3 148 ? -62.347 82.328 -11.200 1.00 256.82 ? 148 TRP C N 1 ATOM 7703 C CA . TRP C 3 148 ? -62.730 83.647 -11.682 1.00 273.02 ? 148 TRP C CA 1 ATOM 7704 C C . TRP C 3 148 ? -63.457 84.420 -10.588 1.00 281.67 ? 148 TRP C C 1 ATOM 7705 O O . TRP C 3 148 ? -63.913 83.832 -9.607 1.00 285.19 ? 148 TRP C O 1 ATOM 7706 C CB . TRP C 3 148 ? -63.613 83.521 -12.927 1.00 271.34 ? 148 TRP C CB 1 ATOM 7707 C CG . TRP C 3 148 ? -62.979 82.719 -14.031 1.00 270.36 ? 148 TRP C CG 1 ATOM 7708 C CD1 . TRP C 3 148 ? -62.870 81.360 -14.100 1.00 267.50 ? 148 TRP C CD1 1 ATOM 7709 C CD2 . TRP C 3 148 ? -62.372 83.230 -15.226 1.00 270.33 ? 148 TRP C CD2 1 ATOM 7710 N NE1 . TRP C 3 148 ? -62.231 80.994 -15.260 1.00 271.41 ? 148 TRP C NE1 1 ATOM 7711 C CE2 . TRP C 3 148 ? -61.916 82.122 -15.969 1.00 268.37 ? 148 TRP C CE2 1 ATOM 7712 C CE3 . TRP C 3 148 ? -62.172 84.515 -15.739 1.00 267.35 ? 148 TRP C CE3 1 ATOM 7713 C CZ2 . TRP C 3 148 ? -61.270 82.262 -17.197 1.00 264.68 ? 148 TRP C CZ2 1 ATOM 7714 C CZ3 . TRP C 3 148 ? -61.529 84.651 -16.957 1.00 262.30 ? 148 TRP C CZ3 1 ATOM 7715 C CH2 . TRP C 3 148 ? -61.087 83.531 -17.672 1.00 264.26 ? 148 TRP C CH2 1 ATOM 7716 N N . LYS C 3 149 ? -63.553 85.737 -10.752 1.00 283.96 ? 149 LYS C N 1 ATOM 7717 C CA . LYS C 3 149 ? -64.257 86.578 -9.786 1.00 277.12 ? 149 LYS C CA 1 ATOM 7718 C C . LYS C 3 149 ? -65.719 86.168 -9.666 1.00 281.62 ? 149 LYS C C 1 ATOM 7719 O O . LYS C 3 149 ? -66.253 86.057 -8.563 1.00 271.84 ? 149 LYS C O 1 ATOM 7720 C CB . LYS C 3 149 ? -64.148 88.056 -10.164 1.00 261.78 ? 149 LYS C CB 1 ATOM 7721 C CG . LYS C 3 149 ? -62.821 88.691 -9.791 1.00 239.53 ? 149 LYS C CG 1 ATOM 7722 C CD . LYS C 3 149 ? -62.568 88.593 -8.296 1.00 212.78 ? 149 LYS C CD 1 ATOM 7723 C CE . LYS C 3 149 ? -61.226 89.199 -7.920 1.00 174.21 ? 149 LYS C CE 1 ATOM 7724 N NZ . LYS C 3 149 ? -60.980 89.131 -6.453 1.00 132.26 ? 149 LYS C NZ 1 ATOM 7725 N N . VAL C 3 150 ? -66.361 85.947 -10.808 1.00 290.46 ? 150 VAL C N 1 ATOM 7726 C CA . VAL C 3 150 ? -67.703 85.385 -10.827 1.00 277.57 ? 150 VAL C CA 1 ATOM 7727 C C . VAL C 3 150 ? -67.590 83.923 -10.410 1.00 273.82 ? 150 VAL C C 1 ATOM 7728 O O . VAL C 3 150 ? -66.566 83.285 -10.658 1.00 282.21 ? 150 VAL C O 1 ATOM 7729 C CB . VAL C 3 150 ? -68.338 85.488 -12.229 1.00 262.70 ? 150 VAL C CB 1 ATOM 7730 C CG1 . VAL C 3 150 ? -69.810 85.104 -12.185 1.00 242.33 ? 150 VAL C CG1 1 ATOM 7731 C CG2 . VAL C 3 150 ? -68.177 86.897 -12.779 1.00 243.65 ? 150 VAL C CG2 1 ATOM 7732 N N . ASP C 3 151 ? -68.631 83.403 -9.764 1.00 255.84 ? 151 ASP C N 1 ATOM 7733 C CA . ASP C 3 151 ? -68.629 82.028 -9.272 1.00 237.60 ? 151 ASP C CA 1 ATOM 7734 C C . ASP C 3 151 ? -68.342 81.038 -10.399 1.00 235.90 ? 151 ASP C C 1 ATOM 7735 O O . ASP C 3 151 ? -69.003 81.054 -11.438 1.00 244.71 ? 151 ASP C O 1 ATOM 7736 C CB . ASP C 3 151 ? -69.970 81.702 -8.609 1.00 221.03 ? 151 ASP C CB 1 ATOM 7737 C CG . ASP C 3 151 ? -69.874 80.542 -7.635 1.00 212.55 ? 151 ASP C CG 1 ATOM 7738 O OD1 . ASP C 3 151 ? -69.011 79.661 -7.831 1.00 223.33 ? 151 ASP C OD1 1 ATOM 7739 O OD2 . ASP C 3 151 ? -70.665 80.513 -6.669 1.00 186.83 ? 151 ASP C OD2 1 ATOM 7740 N N . ASN C 3 152 ? -67.350 80.180 -10.184 1.00 227.59 ? 152 ASN C N 1 ATOM 7741 C CA . ASN C 3 152 ? -66.929 79.223 -11.200 1.00 220.07 ? 152 ASN C CA 1 ATOM 7742 C C . ASN C 3 152 ? -67.918 78.070 -11.319 1.00 202.67 ? 152 ASN C C 1 ATOM 7743 O O . ASN C 3 152 ? -68.211 77.386 -10.337 1.00 192.84 ? 152 ASN C O 1 ATOM 7744 C CB . ASN C 3 152 ? -65.536 78.699 -10.888 1.00 218.19 ? 152 ASN C CB 1 ATOM 7745 N N . ALA C 3 153 ? -68.427 77.858 -12.529 1.00 201.66 ? 153 ALA C N 1 ATOM 7746 C CA . ALA C 3 153 ? -69.402 76.802 -12.777 1.00 201.33 ? 153 ALA C CA 1 ATOM 7747 C C . ALA C 3 153 ? -69.351 76.318 -14.223 1.00 214.92 ? 153 ALA C C 1 ATOM 7748 O O . ALA C 3 153 ? -68.533 76.784 -15.017 1.00 225.01 ? 153 ALA C O 1 ATOM 7749 C CB . ALA C 3 153 ? -70.803 77.284 -12.428 1.00 202.61 ? 153 ALA C CB 1 ATOM 7750 N N . LEU C 3 154 ? -70.234 75.382 -14.555 1.00 211.60 ? 154 LEU C N 1 ATOM 7751 C CA . LEU C 3 154 ? -70.287 74.809 -15.896 1.00 220.86 ? 154 LEU C CA 1 ATOM 7752 C C . LEU C 3 154 ? -70.962 75.747 -16.891 1.00 235.90 ? 154 LEU C C 1 ATOM 7753 O O . LEU C 3 154 ? -70.693 75.688 -18.091 1.00 241.18 ? 154 LEU C O 1 ATOM 7754 C CB . LEU C 3 154 ? -71.022 73.466 -15.872 1.00 212.80 ? 154 LEU C CB 1 ATOM 7755 C CG . LEU C 3 154 ? -70.362 72.333 -15.085 1.00 189.82 ? 154 LEU C CG 1 ATOM 7756 C CD1 . LEU C 3 154 ? -71.314 71.155 -14.945 1.00 163.86 ? 154 LEU C CD1 1 ATOM 7757 C CD2 . LEU C 3 154 ? -69.073 71.901 -15.761 1.00 181.47 ? 154 LEU C CD2 1 ATOM 7758 N N . GLN C 3 155 ? -71.840 76.608 -16.386 1.00 242.93 ? 155 GLN C N 1 ATOM 7759 C CA . GLN C 3 155 ? -72.591 77.530 -17.232 1.00 242.54 ? 155 GLN C CA 1 ATOM 7760 C C . GLN C 3 155 ? -71.680 78.547 -17.911 1.00 250.09 ? 155 GLN C C 1 ATOM 7761 O O . GLN C 3 155 ? -71.912 78.937 -19.055 1.00 246.03 ? 155 GLN C O 1 ATOM 7762 C CB . GLN C 3 155 ? -73.665 78.238 -16.418 1.00 227.64 ? 155 GLN C CB 1 ATOM 7763 N N . SER C 3 156 ? -70.644 78.974 -17.196 1.00 250.99 ? 156 SER C N 1 ATOM 7764 C CA . SER C 3 156 ? -69.693 79.941 -17.727 1.00 252.97 ? 156 SER C CA 1 ATOM 7765 C C . SER C 3 156 ? -68.649 79.268 -18.611 1.00 264.33 ? 156 SER C C 1 ATOM 7766 O O . SER C 3 156 ? -67.959 79.929 -19.389 1.00 269.31 ? 156 SER C O 1 ATOM 7767 C CB . SER C 3 156 ? -69.005 80.688 -16.585 1.00 252.11 ? 156 SER C CB 1 ATOM 7768 O OG . SER C 3 156 ? -67.942 81.487 -17.069 1.00 260.93 ? 156 SER C OG 1 ATOM 7769 N N . GLY C 3 157 ? -68.539 77.950 -18.488 1.00 263.30 ? 157 GLY C N 1 ATOM 7770 C CA . GLY C 3 157 ? -67.552 77.197 -19.238 1.00 257.61 ? 157 GLY C CA 1 ATOM 7771 C C . GLY C 3 157 ? -66.171 77.313 -18.623 1.00 273.68 ? 157 GLY C C 1 ATOM 7772 O O . GLY C 3 157 ? -65.172 76.955 -19.244 1.00 278.78 ? 157 GLY C O 1 ATOM 7773 N N . ASN C 3 158 ? -66.117 77.821 -17.395 1.00 277.60 ? 158 ASN C N 1 ATOM 7774 C CA . ASN C 3 158 ? -64.855 77.965 -16.682 1.00 274.97 ? 158 ASN C CA 1 ATOM 7775 C C . ASN C 3 158 ? -64.267 76.614 -16.296 1.00 272.35 ? 158 ASN C C 1 ATOM 7776 O O . ASN C 3 158 ? -63.049 76.457 -16.207 1.00 271.44 ? 158 ASN C O 1 ATOM 7777 C CB . ASN C 3 158 ? -65.036 78.837 -15.437 1.00 256.47 ? 158 ASN C CB 1 ATOM 7778 C CG . ASN C 3 158 ? -65.408 80.266 -15.776 1.00 254.27 ? 158 ASN C CG 1 ATOM 7779 O OD1 . ASN C 3 158 ? -65.095 80.761 -16.859 1.00 265.66 ? 158 ASN C OD1 1 ATOM 7780 N ND2 . ASN C 3 158 ? -66.074 80.941 -14.846 1.00 235.14 ? 158 ASN C ND2 1 ATOM 7781 N N . SER C 3 159 ? -65.143 75.640 -16.069 1.00 266.23 ? 159 SER C N 1 ATOM 7782 C CA . SER C 3 159 ? -64.720 74.289 -15.725 1.00 250.07 ? 159 SER C CA 1 ATOM 7783 C C . SER C 3 159 ? -64.203 73.546 -16.951 1.00 266.52 ? 159 SER C C 1 ATOM 7784 O O . SER C 3 159 ? -63.614 72.471 -16.833 1.00 264.11 ? 159 SER C O 1 ATOM 7785 C CB . SER C 3 159 ? -65.869 73.509 -15.086 1.00 223.75 ? 159 SER C CB 1 ATOM 7786 O OG . SER C 3 159 ? -65.479 72.178 -14.795 1.00 199.12 ? 159 SER C OG 1 ATOM 7787 N N . GLN C 3 160 ? -64.424 74.123 -18.128 1.00 277.82 ? 160 GLN C N 1 ATOM 7788 C CA . GLN C 3 160 ? -63.915 73.538 -19.358 1.00 271.93 ? 160 GLN C CA 1 ATOM 7789 C C . GLN C 3 160 ? -62.439 73.880 -19.503 1.00 265.50 ? 160 GLN C C 1 ATOM 7790 O O . GLN C 3 160 ? -62.070 75.049 -19.613 1.00 268.54 ? 160 GLN C O 1 ATOM 7791 C CB . GLN C 3 160 ? -64.692 74.070 -20.562 1.00 261.83 ? 160 GLN C CB 1 ATOM 7792 C CG . GLN C 3 160 ? -64.001 73.840 -21.893 1.00 249.37 ? 160 GLN C CG 1 ATOM 7793 C CD . GLN C 3 160 ? -64.701 74.533 -23.042 1.00 243.51 ? 160 GLN C CD 1 ATOM 7794 O OE1 . GLN C 3 160 ? -65.737 75.173 -22.859 1.00 242.85 ? 160 GLN C OE1 1 ATOM 7795 N NE2 . GLN C 3 160 ? -64.136 74.413 -24.236 1.00 243.83 ? 160 GLN C NE2 1 ATOM 7796 N N . GLU C 3 161 ? -61.599 72.851 -19.506 1.00 252.27 ? 161 GLU C N 1 ATOM 7797 C CA . GLU C 3 161 ? -60.157 73.040 -19.608 1.00 254.43 ? 161 GLU C CA 1 ATOM 7798 C C . GLU C 3 161 ? -59.514 71.977 -20.492 1.00 247.02 ? 161 GLU C C 1 ATOM 7799 O O . GLU C 3 161 ? -59.728 70.780 -20.296 1.00 232.88 ? 161 GLU C O 1 ATOM 7800 C CB . GLU C 3 161 ? -59.510 73.040 -18.218 1.00 257.93 ? 161 GLU C CB 1 ATOM 7801 C CG . GLU C 3 161 ? -59.873 74.245 -17.359 1.00 260.98 ? 161 GLU C CG 1 ATOM 7802 C CD . GLU C 3 161 ? -59.205 74.224 -15.998 1.00 251.66 ? 161 GLU C CD 1 ATOM 7803 O OE1 . GLU C 3 161 ? -58.430 73.282 -15.729 1.00 238.68 ? 161 GLU C OE1 1 ATOM 7804 O OE2 . GLU C 3 161 ? -59.455 75.150 -15.197 1.00 248.89 ? 161 GLU C OE2 1 ATOM 7805 N N . SER C 3 162 ? -58.725 72.423 -21.464 1.00 251.88 ? 162 SER C N 1 ATOM 7806 C CA . SER C 3 162 ? -57.993 71.512 -22.335 1.00 241.11 ? 162 SER C CA 1 ATOM 7807 C C . SER C 3 162 ? -56.494 71.737 -22.181 1.00 231.77 ? 162 SER C C 1 ATOM 7808 O O . SER C 3 162 ? -56.022 72.873 -22.227 1.00 239.71 ? 162 SER C O 1 ATOM 7809 C CB . SER C 3 162 ? -58.403 71.713 -23.793 1.00 245.50 ? 162 SER C CB 1 ATOM 7810 O OG . SER C 3 162 ? -57.775 70.762 -24.634 1.00 247.38 ? 162 SER C OG 1 ATOM 7811 N N . VAL C 3 163 ? -55.750 70.652 -21.995 1.00 218.60 ? 163 VAL C N 1 ATOM 7812 C CA . VAL C 3 163 ? -54.307 70.744 -21.819 1.00 229.43 ? 163 VAL C CA 1 ATOM 7813 C C . VAL C 3 163 ? -53.563 69.966 -22.898 1.00 222.14 ? 163 VAL C C 1 ATOM 7814 O O . VAL C 3 163 ? -53.747 68.758 -23.045 1.00 209.86 ? 163 VAL C O 1 ATOM 7815 C CB . VAL C 3 163 ? -53.872 70.219 -20.439 1.00 231.49 ? 163 VAL C CB 1 ATOM 7816 C CG1 . VAL C 3 163 ? -52.363 70.326 -20.283 1.00 226.39 ? 163 VAL C CG1 1 ATOM 7817 C CG2 . VAL C 3 163 ? -54.585 70.982 -19.333 1.00 224.60 ? 163 VAL C CG2 1 ATOM 7818 N N . THR C 3 164 ? -52.724 70.669 -23.653 1.00 229.57 ? 164 THR C N 1 ATOM 7819 C CA . THR C 3 164 ? -51.888 70.032 -24.662 1.00 237.13 ? 164 THR C CA 1 ATOM 7820 C C . THR C 3 164 ? -50.821 69.165 -24.011 1.00 225.28 ? 164 THR C C 1 ATOM 7821 O O . THR C 3 164 ? -50.481 69.353 -22.844 1.00 217.45 ? 164 THR C O 1 ATOM 7822 C CB . THR C 3 164 ? -51.188 71.070 -25.560 1.00 248.49 ? 164 THR C CB 1 ATOM 7823 O OG1 . THR C 3 164 ? -50.844 72.225 -24.783 1.00 245.45 ? 164 THR C OG1 1 ATOM 7824 C CG2 . THR C 3 164 ? -52.094 71.486 -26.705 1.00 258.91 ? 164 THR C CG2 1 ATOM 7825 N N . GLU C 3 165 ? -50.297 68.212 -24.775 1.00 223.36 ? 165 GLU C N 1 ATOM 7826 C CA . GLU C 3 165 ? -49.188 67.389 -24.317 1.00 217.51 ? 165 GLU C CA 1 ATOM 7827 C C . GLU C 3 165 ? -47.932 68.249 -24.262 1.00 222.69 ? 165 GLU C C 1 ATOM 7828 O O . GLU C 3 165 ? -47.885 69.319 -24.870 1.00 205.02 ? 165 GLU C O 1 ATOM 7829 C CB . GLU C 3 165 ? -48.983 66.195 -25.251 1.00 219.85 ? 165 GLU C CB 1 ATOM 7830 C CG . GLU C 3 165 ? -50.270 65.465 -25.610 1.00 213.84 ? 165 GLU C CG 1 ATOM 7831 C CD . GLU C 3 165 ? -51.002 64.926 -24.396 1.00 201.26 ? 165 GLU C CD 1 ATOM 7832 O OE1 . GLU C 3 165 ? -50.334 64.503 -23.429 1.00 200.13 ? 165 GLU C OE1 1 ATOM 7833 O OE2 . GLU C 3 165 ? -52.251 64.926 -24.409 1.00 185.45 ? 165 GLU C OE2 1 ATOM 7834 N N . GLN C 3 166 ? -46.927 67.793 -23.519 1.00 235.31 ? 166 GLN C N 1 ATOM 7835 C CA . GLN C 3 166 ? -45.684 68.543 -23.361 1.00 235.65 ? 166 GLN C CA 1 ATOM 7836 C C . GLN C 3 166 ? -45.053 68.910 -24.698 1.00 241.71 ? 166 GLN C C 1 ATOM 7837 O O . GLN C 3 166 ? -45.070 68.119 -25.642 1.00 244.30 ? 166 GLN C O 1 ATOM 7838 C CB . GLN C 3 166 ? -44.673 67.744 -22.536 1.00 229.60 ? 166 GLN C CB 1 ATOM 7839 C CG . GLN C 3 166 ? -44.982 67.674 -21.055 1.00 228.51 ? 166 GLN C CG 1 ATOM 7840 C CD . GLN C 3 166 ? -43.937 66.895 -20.280 1.00 221.42 ? 166 GLN C CD 1 ATOM 7841 O OE1 . GLN C 3 166 ? -43.019 66.317 -20.861 1.00 208.07 ? 166 GLN C OE1 1 ATOM 7842 N NE2 . GLN C 3 166 ? -44.072 66.877 -18.959 1.00 216.36 ? 166 GLN C NE2 1 ATOM 7843 N N . ASP C 3 167 ? -44.506 70.118 -24.771 1.00 245.21 ? 167 ASP C N 1 ATOM 7844 C CA . ASP C 3 167 ? -43.766 70.547 -25.947 1.00 246.27 ? 167 ASP C CA 1 ATOM 7845 C C . ASP C 3 167 ? -42.532 69.666 -26.084 1.00 248.47 ? 167 ASP C C 1 ATOM 7846 O O . ASP C 3 167 ? -41.921 69.285 -25.086 1.00 250.46 ? 167 ASP C O 1 ATOM 7847 C CB . ASP C 3 167 ? -43.371 72.020 -25.826 1.00 239.76 ? 167 ASP C CB 1 ATOM 7848 C CG . ASP C 3 167 ? -42.666 72.539 -27.063 1.00 232.23 ? 167 ASP C CG 1 ATOM 7849 O OD1 . ASP C 3 167 ? -41.423 72.656 -27.036 1.00 238.21 ? 167 ASP C OD1 1 ATOM 7850 O OD2 . ASP C 3 167 ? -43.354 72.831 -28.064 1.00 211.35 ? 167 ASP C OD2 1 ATOM 7851 N N . SER C 3 168 ? -42.168 69.342 -27.320 1.00 238.49 ? 168 SER C N 1 ATOM 7852 C CA . SER C 3 168 ? -41.092 68.389 -27.581 1.00 227.97 ? 168 SER C CA 1 ATOM 7853 C C . SER C 3 168 ? -39.717 68.884 -27.134 1.00 236.44 ? 168 SER C C 1 ATOM 7854 O O . SER C 3 168 ? -38.748 68.124 -27.134 1.00 239.32 ? 168 SER C O 1 ATOM 7855 C CB . SER C 3 168 ? -41.058 68.016 -29.065 1.00 208.03 ? 168 SER C CB 1 ATOM 7856 O OG . SER C 3 168 ? -40.857 69.162 -29.874 1.00 218.43 ? 168 SER C OG 1 ATOM 7857 N N . LYS C 3 169 ? -39.635 70.154 -26.753 1.00 240.17 ? 169 LYS C N 1 ATOM 7858 C CA . LYS C 3 169 ? -38.367 70.745 -26.339 1.00 234.64 ? 169 LYS C CA 1 ATOM 7859 C C . LYS C 3 169 ? -38.272 70.923 -24.825 1.00 229.71 ? 169 LYS C C 1 ATOM 7860 O O . LYS C 3 169 ? -37.538 70.201 -24.151 1.00 206.16 ? 169 LYS C O 1 ATOM 7861 C CB . LYS C 3 169 ? -38.150 72.076 -27.045 1.00 226.56 ? 169 LYS C CB 1 ATOM 7862 N N . ASP C 3 170 ? -39.022 71.886 -24.296 1.00 239.27 ? 170 ASP C N 1 ATOM 7863 C CA . ASP C 3 170 ? -38.929 72.244 -22.884 1.00 236.20 ? 170 ASP C CA 1 ATOM 7864 C C . ASP C 3 170 ? -39.735 71.327 -21.967 1.00 249.52 ? 170 ASP C C 1 ATOM 7865 O O . ASP C 3 170 ? -39.631 71.421 -20.743 1.00 248.07 ? 170 ASP C O 1 ATOM 7866 C CB . ASP C 3 170 ? -39.349 73.703 -22.674 1.00 232.42 ? 170 ASP C CB 1 ATOM 7867 C CG . ASP C 3 170 ? -40.680 74.031 -23.329 1.00 240.01 ? 170 ASP C CG 1 ATOM 7868 O OD1 . ASP C 3 170 ? -41.572 73.157 -23.359 1.00 241.54 ? 170 ASP C OD1 1 ATOM 7869 O OD2 . ASP C 3 170 ? -40.836 75.171 -23.816 1.00 241.79 ? 170 ASP C OD2 1 ATOM 7870 N N . SER C 3 171 ? -40.529 70.443 -22.567 1.00 256.61 ? 171 SER C N 1 ATOM 7871 C CA . SER C 3 171 ? -41.414 69.542 -21.828 1.00 253.96 ? 171 SER C CA 1 ATOM 7872 C C . SER C 3 171 ? -42.345 70.309 -20.891 1.00 252.23 ? 171 SER C C 1 ATOM 7873 O O . SER C 3 171 ? -42.527 69.934 -19.734 1.00 248.72 ? 171 SER C O 1 ATOM 7874 C CB . SER C 3 171 ? -40.615 68.490 -21.050 1.00 245.78 ? 171 SER C CB 1 ATOM 7875 O OG . SER C 3 171 ? -39.915 69.068 -19.962 1.00 231.43 ? 171 SER C OG 1 ATOM 7876 N N . THR C 3 172 ? -42.931 71.386 -21.405 1.00 249.01 ? 172 THR C N 1 ATOM 7877 C CA . THR C 3 172 ? -43.842 72.214 -20.623 1.00 242.99 ? 172 THR C CA 1 ATOM 7878 C C . THR C 3 172 ? -45.241 72.202 -21.233 1.00 235.69 ? 172 THR C C 1 ATOM 7879 O O . THR C 3 172 ? -45.396 72.048 -22.445 1.00 221.04 ? 172 THR C O 1 ATOM 7880 C CB . THR C 3 172 ? -43.343 73.664 -20.534 1.00 240.77 ? 172 THR C CB 1 ATOM 7881 O OG1 . THR C 3 172 ? -43.315 74.240 -21.845 1.00 240.76 ? 172 THR C OG1 1 ATOM 7882 C CG2 . THR C 3 172 ? -41.945 73.713 -19.937 1.00 225.67 ? 172 THR C CG2 1 ATOM 7883 N N . TYR C 3 173 ? -46.258 72.364 -20.391 1.00 240.22 ? 173 TYR C N 1 ATOM 7884 C CA . TYR C 3 173 ? -47.643 72.284 -20.849 1.00 231.76 ? 173 TYR C CA 1 ATOM 7885 C C . TYR C 3 173 ? -48.220 73.643 -21.224 1.00 226.23 ? 173 TYR C C 1 ATOM 7886 O O . TYR C 3 173 ? -47.571 74.675 -21.065 1.00 223.85 ? 173 TYR C O 1 ATOM 7887 C CB . TYR C 3 173 ? -48.523 71.644 -19.774 1.00 228.98 ? 173 TYR C CB 1 ATOM 7888 C CG . TYR C 3 173 ? -48.195 70.197 -19.493 1.00 229.19 ? 173 TYR C CG 1 ATOM 7889 C CD1 . TYR C 3 173 ? -47.303 69.848 -18.488 1.00 227.15 ? 173 TYR C CD1 1 ATOM 7890 C CD2 . TYR C 3 173 ? -48.781 69.178 -20.232 1.00 222.81 ? 173 TYR C CD2 1 ATOM 7891 C CE1 . TYR C 3 173 ? -47.002 68.526 -18.229 1.00 222.80 ? 173 TYR C CE1 1 ATOM 7892 C CE2 . TYR C 3 173 ? -48.486 67.854 -19.981 1.00 219.49 ? 173 TYR C CE2 1 ATOM 7893 C CZ . TYR C 3 173 ? -47.599 67.533 -18.978 1.00 223.37 ? 173 TYR C CZ 1 ATOM 7894 O OH . TYR C 3 173 ? -47.305 66.214 -18.731 1.00 227.95 ? 173 TYR C OH 1 ATOM 7895 N N . SER C 3 174 ? -49.453 73.627 -21.720 1.00 226.39 ? 174 SER C N 1 ATOM 7896 C CA . SER C 3 174 ? -50.189 74.849 -22.018 1.00 235.15 ? 174 SER C CA 1 ATOM 7897 C C . SER C 3 174 ? -51.641 74.693 -21.575 1.00 237.60 ? 174 SER C C 1 ATOM 7898 O O . SER C 3 174 ? -52.326 73.762 -21.996 1.00 236.53 ? 174 SER C O 1 ATOM 7899 C CB . SER C 3 174 ? -50.114 75.179 -23.511 1.00 228.76 ? 174 SER C CB 1 ATOM 7900 O OG . SER C 3 174 ? -48.778 75.427 -23.914 1.00 209.88 ? 174 SER C OG 1 ATOM 7901 N N . LEU C 3 175 ? -52.105 75.604 -20.727 1.00 237.54 ? 175 LEU C N 1 ATOM 7902 C CA . LEU C 3 175 ? -53.452 75.514 -20.172 1.00 233.05 ? 175 LEU C CA 1 ATOM 7903 C C . LEU C 3 175 ? -54.333 76.664 -20.646 1.00 246.01 ? 175 LEU C C 1 ATOM 7904 O O . LEU C 3 175 ? -53.889 77.810 -20.719 1.00 250.22 ? 175 LEU C O 1 ATOM 7905 C CB . LEU C 3 175 ? -53.401 75.496 -18.642 1.00 224.55 ? 175 LEU C CB 1 ATOM 7906 C CG . LEU C 3 175 ? -54.166 74.383 -17.921 1.00 222.50 ? 175 LEU C CG 1 ATOM 7907 C CD1 . LEU C 3 175 ? -53.991 74.501 -16.414 1.00 220.53 ? 175 LEU C CD1 1 ATOM 7908 C CD2 . LEU C 3 175 ? -55.641 74.395 -18.294 1.00 232.90 ? 175 LEU C CD2 1 ATOM 7909 N N . SER C 3 176 ? -55.584 76.349 -20.966 1.00 255.70 ? 176 SER C N 1 ATOM 7910 C CA . SER C 3 176 ? -56.537 77.357 -21.417 1.00 271.96 ? 176 SER C CA 1 ATOM 7911 C C . SER C 3 176 ? -57.892 77.201 -20.732 1.00 280.71 ? 176 SER C C 1 ATOM 7912 O O . SER C 3 176 ? -58.542 76.162 -20.849 1.00 272.45 ? 176 SER C O 1 ATOM 7913 C CB . SER C 3 176 ? -56.708 77.285 -22.935 1.00 270.83 ? 176 SER C CB 1 ATOM 7914 O OG . SER C 3 176 ? -57.179 76.010 -23.334 1.00 248.60 ? 176 SER C OG 1 ATOM 7915 N N . SER C 3 177 ? -58.309 78.239 -20.014 1.00 297.15 ? 177 SER C N 1 ATOM 7916 C CA . SER C 3 177 ? -59.633 78.271 -19.404 1.00 295.52 ? 177 SER C CA 1 ATOM 7917 C C . SER C 3 177 ? -60.503 79.292 -20.129 1.00 300.98 ? 177 SER C C 1 ATOM 7918 O O . SER C 3 177 ? -60.251 80.495 -20.060 1.00 297.98 ? 177 SER C O 1 ATOM 7919 C CB . SER C 3 177 ? -59.538 78.612 -17.916 1.00 281.94 ? 177 SER C CB 1 ATOM 7920 O OG . SER C 3 177 ? -60.819 78.616 -17.311 1.00 272.07 ? 177 SER C OG 1 ATOM 7921 N N . THR C 3 178 ? -61.527 78.806 -20.824 1.00 303.95 ? 178 THR C N 1 ATOM 7922 C CA . THR C 3 178 ? -62.344 79.655 -21.684 1.00 306.97 ? 178 THR C CA 1 ATOM 7923 C C . THR C 3 178 ? -63.577 80.219 -20.977 1.00 306.89 ? 178 THR C C 1 ATOM 7924 O O . THR C 3 178 ? -64.378 79.473 -20.415 1.00 308.26 ? 178 THR C O 1 ATOM 7925 C CB . THR C 3 178 ? -62.793 78.895 -22.949 1.00 301.46 ? 178 THR C CB 1 ATOM 7926 O OG1 . THR C 3 178 ? -61.641 78.458 -23.681 1.00 296.97 ? 178 THR C OG1 1 ATOM 7927 C CG2 . THR C 3 178 ? -63.642 79.786 -23.838 1.00 300.07 ? 178 THR C CG2 1 ATOM 7928 N N . LEU C 3 179 ? -63.717 81.541 -21.012 1.00 300.30 ? 179 LEU C N 1 ATOM 7929 C CA . LEU C 3 179 ? -64.901 82.213 -20.483 1.00 283.63 ? 179 LEU C CA 1 ATOM 7930 C C . LEU C 3 179 ? -65.794 82.686 -21.626 1.00 280.29 ? 179 LEU C C 1 ATOM 7931 O O . LEU C 3 179 ? -65.431 83.593 -22.376 1.00 274.15 ? 179 LEU C O 1 ATOM 7932 C CB . LEU C 3 179 ? -64.498 83.394 -19.593 1.00 267.05 ? 179 LEU C CB 1 ATOM 7933 C CG . LEU C 3 179 ? -65.523 84.504 -19.330 1.00 247.31 ? 179 LEU C CG 1 ATOM 7934 C CD1 . LEU C 3 179 ? -66.734 83.983 -18.575 1.00 241.30 ? 179 LEU C CD1 1 ATOM 7935 C CD2 . LEU C 3 179 ? -64.881 85.665 -18.582 1.00 230.32 ? 179 LEU C CD2 1 ATOM 7936 N N . THR C 3 180 ? -66.957 82.056 -21.763 1.00 285.82 ? 180 THR C N 1 ATOM 7937 C CA . THR C 3 180 ? -67.908 82.422 -22.807 1.00 289.25 ? 180 THR C CA 1 ATOM 7938 C C . THR C 3 180 ? -69.338 82.490 -22.282 1.00 279.54 ? 180 THR C C 1 ATOM 7939 O O . THR C 3 180 ? -69.868 81.507 -21.763 1.00 274.03 ? 180 THR C O 1 ATOM 7940 C CB . THR C 3 180 ? -67.860 81.440 -23.996 1.00 288.27 ? 180 THR C CB 1 ATOM 7941 O OG1 . THR C 3 180 ? -67.874 80.092 -23.507 1.00 289.49 ? 180 THR C OG1 1 ATOM 7942 C CG2 . THR C 3 180 ? -66.605 81.661 -24.826 1.00 282.30 ? 180 THR C CG2 1 ATOM 7943 N N . LEU C 3 181 ? -69.957 83.658 -22.418 1.00 274.45 ? 181 LEU C N 1 ATOM 7944 C CA . LEU C 3 181 ? -71.363 83.821 -22.073 1.00 256.89 ? 181 LEU C CA 1 ATOM 7945 C C . LEU C 3 181 ? -72.185 84.111 -23.323 1.00 253.19 ? 181 LEU C C 1 ATOM 7946 O O . LEU C 3 181 ? -72.065 85.180 -23.922 1.00 249.92 ? 181 LEU C O 1 ATOM 7947 C CB . LEU C 3 181 ? -71.547 84.938 -21.043 1.00 241.46 ? 181 LEU C CB 1 ATOM 7948 C CG . LEU C 3 181 ? -71.106 84.622 -19.613 1.00 211.95 ? 181 LEU C CG 1 ATOM 7949 C CD1 . LEU C 3 181 ? -71.305 85.829 -18.709 1.00 201.76 ? 181 LEU C CD1 1 ATOM 7950 C CD2 . LEU C 3 181 ? -71.862 83.417 -19.075 1.00 194.10 ? 181 LEU C CD2 1 ATOM 7951 N N . SER C 3 182 ? -73.016 83.151 -23.714 1.00 247.03 ? 182 SER C N 1 ATOM 7952 C CA . SER C 3 182 ? -73.857 83.306 -24.893 1.00 231.83 ? 182 SER C CA 1 ATOM 7953 C C . SER C 3 182 ? -74.960 84.326 -24.637 1.00 229.78 ? 182 SER C C 1 ATOM 7954 O O . SER C 3 182 ? -75.587 84.321 -23.577 1.00 223.76 ? 182 SER C O 1 ATOM 7955 C CB . SER C 3 182 ? -74.460 81.962 -25.307 1.00 223.66 ? 182 SER C CB 1 ATOM 7956 O OG . SER C 3 182 ? -75.236 81.406 -24.260 1.00 220.95 ? 182 SER C OG 1 ATOM 7957 N N . LYS C 3 183 ? -75.173 85.204 -25.613 1.00 232.80 ? 183 LYS C N 1 ATOM 7958 C CA . LYS C 3 183 ? -76.203 86.241 -25.546 1.00 225.48 ? 183 LYS C CA 1 ATOM 7959 C C . LYS C 3 183 ? -76.001 87.217 -24.385 1.00 233.63 ? 183 LYS C C 1 ATOM 7960 O O . LYS C 3 183 ? -76.953 87.851 -23.928 1.00 231.54 ? 183 LYS C O 1 ATOM 7961 C CB . LYS C 3 183 ? -77.601 85.613 -25.498 1.00 194.97 ? 183 LYS C CB 1 ATOM 7962 C CG . LYS C 3 183 ? -77.863 84.621 -26.622 1.00 158.19 ? 183 LYS C CG 1 ATOM 7963 C CD . LYS C 3 183 ? -79.166 83.868 -26.414 1.00 116.10 ? 183 LYS C CD 1 ATOM 7964 C CE . LYS C 3 183 ? -79.362 82.813 -27.491 1.00 106.85 ? 183 LYS C CE 1 ATOM 7965 N NZ . LYS C 3 183 ? -80.613 82.033 -27.290 1.00 102.28 ? 183 LYS C NZ 1 ATOM 7966 N N . ALA C 3 184 ? -74.757 87.329 -23.924 1.00 231.66 ? 184 ALA C N 1 ATOM 7967 C CA . ALA C 3 184 ? -74.354 88.339 -22.942 1.00 220.46 ? 184 ALA C CA 1 ATOM 7968 C C . ALA C 3 184 ? -75.202 88.389 -21.669 1.00 217.12 ? 184 ALA C C 1 ATOM 7969 O O . ALA C 3 184 ? -75.954 89.341 -21.460 1.00 221.31 ? 184 ALA C O 1 ATOM 7970 C CB . ALA C 3 184 ? -74.294 89.718 -23.593 1.00 222.24 ? 184 ALA C CB 1 ATOM 7971 N N . ASP C 3 185 ? -75.083 87.370 -20.825 1.00 211.44 ? 185 ASP C N 1 ATOM 7972 C CA . ASP C 3 185 ? -75.788 87.367 -19.547 1.00 212.74 ? 185 ASP C CA 1 ATOM 7973 C C . ASP C 3 185 ? -75.088 88.277 -18.543 1.00 200.97 ? 185 ASP C C 1 ATOM 7974 O O . ASP C 3 185 ? -75.731 89.074 -17.859 1.00 197.03 ? 185 ASP C O 1 ATOM 7975 C CB . ASP C 3 185 ? -75.899 85.950 -18.983 1.00 211.11 ? 185 ASP C CB 1 ATOM 7976 C CG . ASP C 3 185 ? -76.690 85.899 -17.689 1.00 204.00 ? 185 ASP C CG 1 ATOM 7977 O OD1 . ASP C 3 185 ? -77.637 86.700 -17.539 1.00 203.14 ? 185 ASP C OD1 1 ATOM 7978 O OD2 . ASP C 3 185 ? -76.363 85.062 -16.821 1.00 192.43 ? 185 ASP C OD2 1 ATOM 7979 N N . VAL C 3 191 ? -67.372 91.734 -12.685 1.00 206.68 ? 191 VAL C N 1 ATOM 7980 C CA . VAL C 3 191 ? -65.930 91.661 -12.483 1.00 234.67 ? 191 VAL C CA 1 ATOM 7981 C C . VAL C 3 191 ? -65.391 90.305 -12.929 1.00 247.93 ? 191 VAL C C 1 ATOM 7982 O O . VAL C 3 191 ? -65.961 89.265 -12.603 1.00 250.99 ? 191 VAL C O 1 ATOM 7983 C CB . VAL C 3 191 ? -65.556 91.894 -11.006 1.00 212.46 ? 191 VAL C CB 1 ATOM 7984 C CG1 . VAL C 3 191 ? -64.047 91.981 -10.847 1.00 219.34 ? 191 VAL C CG1 1 ATOM 7985 C CG2 . VAL C 3 191 ? -66.218 93.160 -10.487 1.00 170.53 ? 191 VAL C CG2 1 ATOM 7986 N N . TYR C 3 192 ? -64.295 90.324 -13.680 1.00 255.54 ? 192 TYR C N 1 ATOM 7987 C CA . TYR C 3 192 ? -63.678 89.094 -14.165 1.00 262.77 ? 192 TYR C CA 1 ATOM 7988 C C . TYR C 3 192 ? -62.180 89.077 -13.881 1.00 276.34 ? 192 TYR C C 1 ATOM 7989 O O . TYR C 3 192 ? -61.505 90.099 -13.989 1.00 281.75 ? 192 TYR C O 1 ATOM 7990 C CB . TYR C 3 192 ? -63.941 88.920 -15.653 1.00 250.29 ? 192 TYR C CB 1 ATOM 7991 N N . ALA C 3 193 ? -61.665 87.911 -13.508 1.00 278.92 ? 193 ALA C N 1 ATOM 7992 C CA . ALA C 3 193 ? -60.242 87.764 -13.234 1.00 277.72 ? 193 ALA C CA 1 ATOM 7993 C C . ALA C 3 193 ? -59.774 86.342 -13.498 1.00 278.24 ? 193 ALA C C 1 ATOM 7994 O O . ALA C 3 193 ? -60.528 85.388 -13.315 1.00 277.94 ? 193 ALA C O 1 ATOM 7995 C CB . ALA C 3 193 ? -59.936 88.153 -11.799 1.00 260.14 ? 193 ALA C CB 1 ATOM 7996 N N . CYS C 3 194 ? -58.523 86.202 -13.917 1.00 273.57 ? 194 CYS C N 1 ATOM 7997 C CA . CYS C 3 194 ? -57.936 84.882 -14.069 1.00 268.82 ? 194 CYS C CA 1 ATOM 7998 C C . CYS C 3 194 ? -57.060 84.614 -12.855 1.00 259.50 ? 194 CYS C C 1 ATOM 7999 O O . CYS C 3 194 ? -55.990 85.203 -12.705 1.00 264.46 ? 194 CYS C O 1 ATOM 8000 C CB . CYS C 3 194 ? -57.108 84.805 -15.354 1.00 265.11 ? 194 CYS C CB 1 ATOM 8001 S SG . CYS C 3 194 ? -56.413 83.172 -15.711 1.00 246.28 ? 194 CYS C SG 1 ATOM 8002 N N . GLU C 3 195 ? -57.526 83.720 -11.988 1.00 250.15 ? 195 GLU C N 1 ATOM 8003 C CA . GLU C 3 195 ? -56.814 83.403 -10.757 1.00 243.05 ? 195 GLU C CA 1 ATOM 8004 C C . GLU C 3 195 ? -56.031 82.112 -10.938 1.00 254.29 ? 195 GLU C C 1 ATOM 8005 O O . GLU C 3 195 ? -56.610 81.035 -11.076 1.00 264.45 ? 195 GLU C O 1 ATOM 8006 C CB . GLU C 3 195 ? -57.794 83.278 -9.588 1.00 241.95 ? 195 GLU C CB 1 ATOM 8007 C CG . GLU C 3 195 ? -57.134 83.124 -8.227 1.00 239.05 ? 195 GLU C CG 1 ATOM 8008 C CD . GLU C 3 195 ? -58.139 83.108 -7.090 1.00 240.35 ? 195 GLU C CD 1 ATOM 8009 O OE1 . GLU C 3 195 ? -57.778 83.528 -5.970 1.00 237.22 ? 195 GLU C OE1 1 ATOM 8010 O OE2 . GLU C 3 195 ? -59.287 82.672 -7.315 1.00 233.63 ? 195 GLU C OE2 1 ATOM 8011 N N . VAL C 3 196 ? -54.708 82.227 -10.936 1.00 256.27 ? 196 VAL C N 1 ATOM 8012 C CA . VAL C 3 196 ? -53.846 81.087 -11.210 1.00 257.12 ? 196 VAL C CA 1 ATOM 8013 C C . VAL C 3 196 ? -53.090 80.639 -9.966 1.00 261.00 ? 196 VAL C C 1 ATOM 8014 O O . VAL C 3 196 ? -52.348 81.414 -9.363 1.00 259.42 ? 196 VAL C O 1 ATOM 8015 C CB . VAL C 3 196 ? -52.836 81.410 -12.324 1.00 237.85 ? 196 VAL C CB 1 ATOM 8016 C CG1 . VAL C 3 196 ? -51.977 80.193 -12.632 1.00 224.32 ? 196 VAL C CG1 1 ATOM 8017 C CG2 . VAL C 3 196 ? -53.565 81.888 -13.569 1.00 238.34 ? 196 VAL C CG2 1 ATOM 8018 N N . THR C 3 197 ? -53.289 79.382 -9.585 1.00 267.97 ? 197 THR C N 1 ATOM 8019 C CA . THR C 3 197 ? -52.572 78.802 -8.459 1.00 258.72 ? 197 THR C CA 1 ATOM 8020 C C . THR C 3 197 ? -51.547 77.799 -8.971 1.00 261.96 ? 197 THR C C 1 ATOM 8021 O O . THR C 3 197 ? -51.904 76.730 -9.467 1.00 270.37 ? 197 THR C O 1 ATOM 8022 C CB . THR C 3 197 ? -53.529 78.094 -7.485 1.00 245.86 ? 197 THR C CB 1 ATOM 8023 O OG1 . THR C 3 197 ? -54.178 77.006 -8.155 1.00 250.31 ? 197 THR C OG1 1 ATOM 8024 C CG2 . THR C 3 197 ? -54.579 79.067 -6.969 1.00 233.50 ? 197 THR C CG2 1 ATOM 8025 N N . HIS C 3 198 ? -50.272 78.150 -8.848 1.00 251.65 ? 198 HIS C N 1 ATOM 8026 C CA . HIS C 3 198 ? -49.194 77.303 -9.342 1.00 240.26 ? 198 HIS C CA 1 ATOM 8027 C C . HIS C 3 198 ? -48.037 77.279 -8.348 1.00 235.33 ? 198 HIS C C 1 ATOM 8028 O O . HIS C 3 198 ? -47.703 78.302 -7.750 1.00 235.87 ? 198 HIS C O 1 ATOM 8029 C CB . HIS C 3 198 ? -48.715 77.797 -10.708 1.00 227.12 ? 198 HIS C CB 1 ATOM 8030 C CG . HIS C 3 198 ? -47.808 76.839 -11.416 1.00 226.63 ? 198 HIS C CG 1 ATOM 8031 N ND1 . HIS C 3 198 ? -46.434 76.936 -11.360 1.00 233.11 ? 198 HIS C ND1 1 ATOM 8032 C CD2 . HIS C 3 198 ? -48.078 75.769 -12.199 1.00 228.68 ? 198 HIS C CD2 1 ATOM 8033 C CE1 . HIS C 3 198 ? -45.897 75.965 -12.076 1.00 237.61 ? 198 HIS C CE1 1 ATOM 8034 N NE2 . HIS C 3 198 ? -46.872 75.242 -12.596 1.00 234.08 ? 198 HIS C NE2 1 ATOM 8035 N N . GLN C 3 199 ? -47.426 76.109 -8.179 1.00 228.69 ? 199 GLN C N 1 ATOM 8036 C CA . GLN C 3 199 ? -46.359 75.931 -7.197 1.00 213.67 ? 199 GLN C CA 1 ATOM 8037 C C . GLN C 3 199 ? -45.110 76.738 -7.545 1.00 215.16 ? 199 GLN C C 1 ATOM 8038 O O . GLN C 3 199 ? -44.289 77.031 -6.676 1.00 207.79 ? 199 GLN C O 1 ATOM 8039 C CB . GLN C 3 199 ? -45.999 74.452 -7.048 1.00 194.98 ? 199 GLN C CB 1 ATOM 8040 C CG . GLN C 3 199 ? -45.199 73.886 -8.210 1.00 197.26 ? 199 GLN C CG 1 ATOM 8041 C CD . GLN C 3 199 ? -44.743 72.462 -7.963 1.00 197.87 ? 199 GLN C CD 1 ATOM 8042 O OE1 . GLN C 3 199 ? -45.480 71.650 -7.404 1.00 208.94 ? 199 GLN C OE1 1 ATOM 8043 N NE2 . GLN C 3 199 ? -43.518 72.154 -8.373 1.00 186.40 ? 199 GLN C NE2 1 ATOM 8044 N N . GLY C 3 200 ? -44.976 77.099 -8.817 1.00 224.63 ? 200 GLY C N 1 ATOM 8045 C CA . GLY C 3 200 ? -43.855 77.901 -9.271 1.00 223.20 ? 200 GLY C CA 1 ATOM 8046 C C . GLY C 3 200 ? -44.063 79.373 -8.977 1.00 225.59 ? 200 GLY C C 1 ATOM 8047 O O . GLY C 3 200 ? -43.277 80.221 -9.402 1.00 220.66 ? 200 GLY C O 1 ATOM 8048 N N . LEU C 3 201 ? -45.131 79.675 -8.247 1.00 231.18 ? 201 LEU C N 1 ATOM 8049 C CA . LEU C 3 201 ? -45.454 81.044 -7.873 1.00 232.81 ? 201 LEU C CA 1 ATOM 8050 C C . LEU C 3 201 ? -45.464 81.186 -6.356 1.00 226.57 ? 201 LEU C C 1 ATOM 8051 O O . LEU C 3 201 ? -45.820 80.249 -5.640 1.00 219.87 ? 201 LEU C O 1 ATOM 8052 C CB . LEU C 3 201 ? -46.814 81.444 -8.446 1.00 233.43 ? 201 LEU C CB 1 ATOM 8053 C CG . LEU C 3 201 ? -47.006 81.205 -9.945 1.00 221.97 ? 201 LEU C CG 1 ATOM 8054 C CD1 . LEU C 3 201 ? -48.403 81.617 -10.382 1.00 219.43 ? 201 LEU C CD1 1 ATOM 8055 C CD2 . LEU C 3 201 ? -45.947 81.945 -10.748 1.00 201.00 ? 201 LEU C CD2 1 ATOM 8056 N N . SER C 3 202 ? -45.070 82.357 -5.869 1.00 228.62 ? 202 SER C N 1 ATOM 8057 C CA . SER C 3 202 ? -45.056 82.621 -4.434 1.00 220.32 ? 202 SER C CA 1 ATOM 8058 C C . SER C 3 202 ? -46.473 82.788 -3.899 1.00 227.21 ? 202 SER C C 1 ATOM 8059 O O . SER C 3 202 ? -46.798 82.317 -2.809 1.00 234.79 ? 202 SER C O 1 ATOM 8060 C CB . SER C 3 202 ? -44.231 83.872 -4.126 1.00 204.78 ? 202 SER C CB 1 ATOM 8061 O OG . SER C 3 202 ? -42.890 83.720 -4.560 1.00 190.22 ? 202 SER C OG 1 ATOM 8062 N N . SER C 3 203 ? -47.312 83.462 -4.678 1.00 225.46 ? 203 SER C N 1 ATOM 8063 C CA . SER C 3 203 ? -48.698 83.693 -4.297 1.00 221.56 ? 203 SER C CA 1 ATOM 8064 C C . SER C 3 203 ? -49.600 83.590 -5.521 1.00 226.05 ? 203 SER C C 1 ATOM 8065 O O . SER C 3 203 ? -49.175 83.898 -6.635 1.00 229.03 ? 203 SER C O 1 ATOM 8066 C CB . SER C 3 203 ? -48.849 85.068 -3.642 1.00 212.61 ? 203 SER C CB 1 ATOM 8067 O OG . SER C 3 203 ? -48.453 86.102 -4.527 1.00 198.38 ? 203 SER C OG 1 ATOM 8068 N N . PRO C 3 204 ? -50.854 83.154 -5.319 1.00 227.51 ? 204 PRO C N 1 ATOM 8069 C CA . PRO C 3 204 ? -51.807 83.021 -6.425 1.00 228.06 ? 204 PRO C CA 1 ATOM 8070 C C . PRO C 3 204 ? -52.149 84.373 -7.045 1.00 227.98 ? 204 PRO C C 1 ATOM 8071 O O . PRO C 3 204 ? -53.274 84.853 -6.899 1.00 206.46 ? 204 PRO C O 1 ATOM 8072 C CB . PRO C 3 204 ? -53.046 82.424 -5.748 1.00 218.04 ? 204 PRO C CB 1 ATOM 8073 C CG . PRO C 3 204 ? -52.524 81.749 -4.526 1.00 220.92 ? 204 PRO C CG 1 ATOM 8074 C CD . PRO C 3 204 ? -51.395 82.614 -4.060 1.00 224.13 ? 204 PRO C CD 1 ATOM 8075 N N . VAL C 3 205 ? -51.176 84.976 -7.724 1.00 235.28 ? 205 VAL C N 1 ATOM 8076 C CA . VAL C 3 205 ? -51.364 86.267 -8.375 1.00 234.31 ? 205 VAL C CA 1 ATOM 8077 C C . VAL C 3 205 ? -52.440 86.192 -9.452 1.00 239.85 ? 205 VAL C C 1 ATOM 8078 O O . VAL C 3 205 ? -52.653 85.142 -10.060 1.00 244.39 ? 205 VAL C O 1 ATOM 8079 C CB . VAL C 3 205 ? -50.051 86.784 -8.998 1.00 218.65 ? 205 VAL C CB 1 ATOM 8080 C CG1 . VAL C 3 205 ? -49.031 87.087 -7.911 1.00 199.36 ? 205 VAL C CG1 1 ATOM 8081 C CG2 . VAL C 3 205 ? -49.496 85.773 -9.990 1.00 220.74 ? 205 VAL C CG2 1 ATOM 8082 N N . THR C 3 206 ? -53.124 87.309 -9.677 1.00 234.50 ? 206 THR C N 1 ATOM 8083 C CA . THR C 3 206 ? -54.222 87.350 -10.634 1.00 236.70 ? 206 THR C CA 1 ATOM 8084 C C . THR C 3 206 ? -54.063 88.487 -11.636 1.00 239.56 ? 206 THR C C 1 ATOM 8085 O O . THR C 3 206 ? -53.695 89.603 -11.271 1.00 236.74 ? 206 THR C O 1 ATOM 8086 C CB . THR C 3 206 ? -55.579 87.527 -9.926 1.00 232.13 ? 206 THR C CB 1 ATOM 8087 O OG1 . THR C 3 206 ? -55.626 88.813 -9.295 1.00 222.00 ? 206 THR C OG1 1 ATOM 8088 C CG2 . THR C 3 206 ? -55.788 86.446 -8.878 1.00 215.93 ? 206 THR C CG2 1 ATOM 8089 N N . LYS C 3 207 ? -54.341 88.192 -12.901 1.00 247.90 ? 207 LYS C N 1 ATOM 8090 C CA . LYS C 3 207 ? -54.419 89.222 -13.926 1.00 249.59 ? 207 LYS C CA 1 ATOM 8091 C C . LYS C 3 207 ? -55.882 89.373 -14.315 1.00 262.03 ? 207 LYS C C 1 ATOM 8092 O O . LYS C 3 207 ? -56.452 88.492 -14.960 1.00 249.39 ? 207 LYS C O 1 ATOM 8093 C CB . LYS C 3 207 ? -53.585 88.827 -15.144 1.00 233.64 ? 207 LYS C CB 1 ATOM 8094 C CG . LYS C 3 207 ? -53.552 89.874 -16.243 1.00 224.57 ? 207 LYS C CG 1 ATOM 8095 C CD . LYS C 3 207 ? -52.647 89.442 -17.385 1.00 209.54 ? 207 LYS C CD 1 ATOM 8096 C CE . LYS C 3 207 ? -52.574 90.508 -18.465 1.00 176.60 ? 207 LYS C CE 1 ATOM 8097 N NZ . LYS C 3 207 ? -51.662 90.114 -19.573 1.00 206.91 ? 207 LYS C NZ 1 ATOM 8098 N N . SER C 3 208 ? -56.493 90.487 -13.926 1.00 284.28 ? 208 SER C N 1 ATOM 8099 C CA . SER C 3 208 ? -57.932 90.629 -14.095 1.00 281.95 ? 208 SER C CA 1 ATOM 8100 C C . SER C 3 208 ? -58.310 91.451 -15.323 1.00 273.42 ? 208 SER C C 1 ATOM 8101 O O . SER C 3 208 ? -57.453 92.027 -15.993 1.00 260.19 ? 208 SER C O 1 ATOM 8102 C CB . SER C 3 208 ? -58.536 91.278 -12.848 1.00 278.68 ? 208 SER C CB 1 ATOM 8103 O OG . SER C 3 208 ? -58.019 90.699 -11.663 1.00 254.27 ? 208 SER C OG 1 ATOM 8104 N N . PHE C 3 209 ? -59.608 91.490 -15.604 1.00 274.44 ? 209 PHE C N 1 ATOM 8105 C CA . PHE C 3 209 ? -60.175 92.383 -16.605 1.00 269.24 ? 209 PHE C CA 1 ATOM 8106 C C . PHE C 3 209 ? -61.587 92.778 -16.181 1.00 267.58 ? 209 PHE C C 1 ATOM 8107 O O . PHE C 3 209 ? -62.379 91.923 -15.791 1.00 269.40 ? 209 PHE C O 1 ATOM 8108 C CB . PHE C 3 209 ? -60.183 91.713 -17.981 1.00 264.84 ? 209 PHE C CB 1 ATOM 8109 C CG . PHE C 3 209 ? -61.034 92.420 -18.996 1.00 263.93 ? 209 PHE C CG 1 ATOM 8110 C CD1 . PHE C 3 209 ? -60.682 93.675 -19.463 1.00 257.54 ? 209 PHE C CD1 1 ATOM 8111 C CD2 . PHE C 3 209 ? -62.181 91.824 -19.491 1.00 266.37 ? 209 PHE C CD2 1 ATOM 8112 C CE1 . PHE C 3 209 ? -61.464 94.325 -20.399 1.00 246.23 ? 209 PHE C CE1 1 ATOM 8113 C CE2 . PHE C 3 209 ? -62.966 92.467 -20.428 1.00 253.85 ? 209 PHE C CE2 1 ATOM 8114 C CZ . PHE C 3 209 ? -62.607 93.720 -20.882 1.00 245.88 ? 209 PHE C CZ 1 ATOM 8115 N N . ASN C 3 210 ? -61.914 94.062 -16.273 1.00 263.64 ? 210 ASN C N 1 ATOM 8116 C CA . ASN C 3 210 ? -63.247 94.513 -15.884 1.00 251.11 ? 210 ASN C CA 1 ATOM 8117 C C . ASN C 3 210 ? -63.858 95.527 -16.846 1.00 244.79 ? 210 ASN C C 1 ATOM 8118 O O . ASN C 3 210 ? -63.217 96.505 -17.232 1.00 245.78 ? 210 ASN C O 1 ATOM 8119 C CB . ASN C 3 210 ? -63.252 95.046 -14.447 1.00 248.73 ? 210 ASN C CB 1 ATOM 8120 C CG . ASN C 3 210 ? -62.071 95.948 -14.152 1.00 248.91 ? 210 ASN C CG 1 ATOM 8121 O OD1 . ASN C 3 210 ? -61.378 96.405 -15.061 1.00 263.91 ? 210 ASN C OD1 1 ATOM 8122 N ND2 . ASN C 3 210 ? -61.835 96.208 -12.872 1.00 213.12 ? 210 ASN C ND2 1 ATOM 8123 N N . ARG C 3 211 ? -65.106 95.278 -17.231 1.00 237.42 ? 211 ARG C N 1 ATOM 8124 C CA . ARG C 3 211 ? -65.813 96.143 -18.166 1.00 223.47 ? 211 ARG C CA 1 ATOM 8125 C C . ARG C 3 211 ? -67.269 96.330 -17.750 1.00 190.29 ? 211 ARG C C 1 ATOM 8126 O O . ARG C 3 211 ? -67.920 95.392 -17.291 1.00 167.54 ? 211 ARG C O 1 ATOM 8127 C CB . ARG C 3 211 ? -65.739 95.569 -19.582 1.00 216.06 ? 211 ARG C CB 1 ATOM 8128 C CG . ARG C 3 211 ? -66.494 96.380 -20.620 1.00 188.93 ? 211 ARG C CG 1 ATOM 8129 C CD . ARG C 3 211 ? -66.320 95.794 -22.011 1.00 154.97 ? 211 ARG C CD 1 ATOM 8130 N NE . ARG C 3 211 ? -64.920 95.774 -22.425 1.00 193.73 ? 211 ARG C NE 1 ATOM 8131 C CZ . ARG C 3 211 ? -64.505 95.420 -23.637 1.00 195.23 ? 211 ARG C CZ 1 ATOM 8132 N NH1 . ARG C 3 211 ? -65.383 95.059 -24.562 1.00 200.70 ? 211 ARG C NH1 1 ATOM 8133 N NH2 . ARG C 3 211 ? -63.211 95.431 -23.926 1.00 169.99 ? 211 ARG C NH2 1 ATOM 8134 N N . GLU D 4 20 ? -44.857 39.881 -37.993 1.00 136.01 ? 1 GLU D N 1 ATOM 8135 C CA . GLU D 4 20 ? -45.758 41.028 -37.999 1.00 137.04 ? 1 GLU D CA 1 ATOM 8136 C C . GLU D 4 20 ? -47.218 40.589 -38.001 1.00 147.23 ? 1 GLU D C 1 ATOM 8137 O O . GLU D 4 20 ? -47.741 40.146 -39.024 1.00 148.85 ? 1 GLU D O 1 ATOM 8138 C CB . GLU D 4 20 ? -45.471 41.920 -39.196 1.00 128.31 ? 1 GLU D CB 1 ATOM 8139 N N . VAL D 4 21 ? -47.870 40.718 -36.849 1.00 151.48 ? 2 VAL D N 1 ATOM 8140 C CA . VAL D 4 21 ? -49.278 40.360 -36.708 1.00 145.80 ? 2 VAL D CA 1 ATOM 8141 C C . VAL D 4 21 ? -50.126 41.607 -36.462 1.00 143.24 ? 2 VAL D C 1 ATOM 8142 O O . VAL D 4 21 ? -49.797 42.430 -35.608 1.00 138.10 ? 2 VAL D O 1 ATOM 8143 C CB . VAL D 4 21 ? -49.486 39.362 -35.552 1.00 136.55 ? 2 VAL D CB 1 ATOM 8144 C CG1 . VAL D 4 21 ? -50.950 38.973 -35.441 1.00 134.63 ? 2 VAL D CG1 1 ATOM 8145 C CG2 . VAL D 4 21 ? -48.616 38.130 -35.754 1.00 136.05 ? 2 VAL D CG2 1 ATOM 8146 N N . GLN D 4 22 ? -51.217 41.745 -37.212 1.00 143.98 ? 3 GLN D N 1 ATOM 8147 C CA . GLN D 4 22 ? -52.061 42.933 -37.117 1.00 147.13 ? 3 GLN D CA 1 ATOM 8148 C C . GLN D 4 22 ? -53.526 42.581 -36.877 1.00 149.07 ? 3 GLN D C 1 ATOM 8149 O O . GLN D 4 22 ? -53.980 41.491 -37.224 1.00 144.66 ? 3 GLN D O 1 ATOM 8150 C CB . GLN D 4 22 ? -51.940 43.775 -38.391 1.00 148.88 ? 3 GLN D CB 1 ATOM 8151 C CG . GLN D 4 22 ? -50.513 43.999 -38.863 1.00 158.14 ? 3 GLN D CG 1 ATOM 8152 C CD . GLN D 4 22 ? -50.444 44.531 -40.281 1.00 163.23 ? 3 GLN D CD 1 ATOM 8153 O OE1 . GLN D 4 22 ? -51.463 44.892 -40.872 1.00 166.01 ? 3 GLN D OE1 1 ATOM 8154 N NE2 . GLN D 4 22 ? -49.239 44.576 -40.838 1.00 157.84 ? 3 GLN D NE2 1 ATOM 8155 N N . LEU D 4 23 ? -54.258 43.515 -36.276 1.00 156.26 ? 4 LEU D N 1 ATOM 8156 C CA . LEU D 4 23 ? -55.696 43.374 -36.077 1.00 154.96 ? 4 LEU D CA 1 ATOM 8157 C C . LEU D 4 23 ? -56.388 44.691 -36.421 1.00 154.55 ? 4 LEU D C 1 ATOM 8158 O O . LEU D 4 23 ? -56.044 45.740 -35.876 1.00 154.21 ? 4 LEU D O 1 ATOM 8159 C CB . LEU D 4 23 ? -56.008 42.977 -34.630 1.00 156.19 ? 4 LEU D CB 1 ATOM 8160 C CG . LEU D 4 23 ? -55.440 41.654 -34.104 1.00 151.34 ? 4 LEU D CG 1 ATOM 8161 C CD1 . LEU D 4 23 ? -55.735 41.489 -32.620 1.00 144.78 ? 4 LEU D CD1 1 ATOM 8162 C CD2 . LEU D 4 23 ? -55.990 40.475 -34.889 1.00 146.79 ? 4 LEU D CD2 1 ATOM 8163 N N . VAL D 4 24 ? -57.354 44.642 -37.333 1.00 154.30 ? 5 VAL D N 1 ATOM 8164 C CA . VAL D 4 24 ? -58.076 45.846 -37.733 1.00 162.57 ? 5 VAL D CA 1 ATOM 8165 C C . VAL D 4 24 ? -59.539 45.781 -37.304 1.00 169.23 ? 5 VAL D C 1 ATOM 8166 O O . VAL D 4 24 ? -60.256 44.840 -37.646 1.00 170.51 ? 5 VAL D O 1 ATOM 8167 C CB . VAL D 4 24 ? -57.989 46.089 -39.253 1.00 167.92 ? 5 VAL D CB 1 ATOM 8168 C CG1 . VAL D 4 24 ? -58.763 47.343 -39.635 1.00 163.92 ? 5 VAL D CG1 1 ATOM 8169 C CG2 . VAL D 4 24 ? -56.535 46.202 -39.690 1.00 167.42 ? 5 VAL D CG2 1 ATOM 8170 N N . GLU D 4 25 ? -59.972 46.789 -36.554 1.00 169.80 ? 6 GLU D N 1 ATOM 8171 C CA . GLU D 4 25 ? -61.321 46.816 -36.001 1.00 164.07 ? 6 GLU D CA 1 ATOM 8172 C C . GLU D 4 25 ? -62.274 47.609 -36.891 1.00 168.77 ? 6 GLU D C 1 ATOM 8173 O O . GLU D 4 25 ? -61.922 48.672 -37.401 1.00 176.62 ? 6 GLU D O 1 ATOM 8174 C CB . GLU D 4 25 ? -61.294 47.418 -34.596 1.00 158.66 ? 6 GLU D CB 1 ATOM 8175 C CG . GLU D 4 25 ? -60.080 47.006 -33.776 1.00 162.58 ? 6 GLU D CG 1 ATOM 8176 C CD . GLU D 4 25 ? -60.028 47.686 -32.423 1.00 165.07 ? 6 GLU D CD 1 ATOM 8177 O OE1 . GLU D 4 25 ? -61.078 48.187 -31.968 1.00 170.76 ? 6 GLU D OE1 1 ATOM 8178 O OE2 . GLU D 4 25 ? -58.936 47.727 -31.817 1.00 161.15 ? 6 GLU D OE2 1 ATOM 8179 N N . SER D 4 26 ? -63.482 47.084 -37.075 1.00 165.00 ? 7 SER D N 1 ATOM 8180 C CA . SER D 4 26 ? -64.502 47.760 -37.869 1.00 164.02 ? 7 SER D CA 1 ATOM 8181 C C . SER D 4 26 ? -65.793 47.898 -37.072 1.00 166.73 ? 7 SER D C 1 ATOM 8182 O O . SER D 4 26 ? -66.390 46.902 -36.664 1.00 166.49 ? 7 SER D O 1 ATOM 8183 C CB . SER D 4 26 ? -64.766 46.999 -39.170 1.00 162.94 ? 7 SER D CB 1 ATOM 8184 O OG . SER D 4 26 ? -65.313 45.719 -38.910 1.00 162.18 ? 7 SER D OG 1 ATOM 8185 N N . GLY D 4 27 ? -66.220 49.137 -36.851 1.00 166.71 ? 8 GLY D N 1 ATOM 8186 C CA . GLY D 4 27 ? -67.414 49.401 -36.071 1.00 162.62 ? 8 GLY D CA 1 ATOM 8187 C C . GLY D 4 27 ? -67.452 50.824 -35.552 1.00 165.39 ? 8 GLY D C 1 ATOM 8188 O O . GLY D 4 27 ? -66.823 51.719 -36.117 1.00 168.75 ? 8 GLY D O 1 ATOM 8189 N N . GLY D 4 28 ? -68.190 51.035 -34.468 1.00 166.68 ? 9 GLY D N 1 ATOM 8190 C CA . GLY D 4 28 ? -68.303 52.352 -33.873 1.00 171.20 ? 9 GLY D CA 1 ATOM 8191 C C . GLY D 4 28 ? -69.459 53.160 -34.423 1.00 170.63 ? 9 GLY D C 1 ATOM 8192 O O . GLY D 4 28 ? -70.475 52.607 -34.844 1.00 162.50 ? 9 GLY D O 1 ATOM 8193 N N . GLY D 4 29 ? -69.300 54.478 -34.415 1.00 175.58 ? 10 GLY D N 1 ATOM 8194 C CA . GLY D 4 29 ? -70.376 55.377 -34.782 1.00 175.75 ? 10 GLY D CA 1 ATOM 8195 C C . GLY D 4 29 ? -71.082 55.846 -33.527 1.00 174.31 ? 10 GLY D C 1 ATOM 8196 O O . GLY D 4 29 ? -70.630 55.567 -32.417 1.00 175.62 ? 10 GLY D O 1 ATOM 8197 N N . VAL D 4 30 ? -72.189 56.560 -33.697 1.00 170.58 ? 11 VAL D N 1 ATOM 8198 C CA . VAL D 4 30 ? -72.957 57.042 -32.555 1.00 173.93 ? 11 VAL D CA 1 ATOM 8199 C C . VAL D 4 30 ? -74.369 56.468 -32.571 1.00 172.41 ? 11 VAL D C 1 ATOM 8200 O O . VAL D 4 30 ? -75.067 56.533 -33.583 1.00 169.41 ? 11 VAL D O 1 ATOM 8201 C CB . VAL D 4 30 ? -73.023 58.581 -32.521 1.00 176.40 ? 11 VAL D CB 1 ATOM 8202 C CG1 . VAL D 4 30 ? -73.749 59.053 -31.269 1.00 177.73 ? 11 VAL D CG1 1 ATOM 8203 C CG2 . VAL D 4 30 ? -71.624 59.170 -32.580 1.00 169.68 ? 11 VAL D CG2 1 ATOM 8204 N N . VAL D 4 31 ? -74.783 55.904 -31.441 1.00 172.05 ? 12 VAL D N 1 ATOM 8205 C CA . VAL D 4 31 ? -76.089 55.273 -31.336 1.00 167.60 ? 12 VAL D CA 1 ATOM 8206 C C . VAL D 4 31 ? -76.860 55.750 -30.107 1.00 168.02 ? 12 VAL D C 1 ATOM 8207 O O . VAL D 4 31 ? -76.317 55.798 -29.000 1.00 166.60 ? 12 VAL D O 1 ATOM 8208 C CB . VAL D 4 31 ? -75.963 53.732 -31.339 1.00 162.68 ? 12 VAL D CB 1 ATOM 8209 C CG1 . VAL D 4 31 ? -77.204 53.083 -30.765 1.00 162.02 ? 12 VAL D CG1 1 ATOM 8210 C CG2 . VAL D 4 31 ? -75.702 53.231 -32.750 1.00 157.14 ? 12 VAL D CG2 1 ATOM 8211 N N . GLN D 4 32 ? -78.122 56.119 -30.327 1.00 167.79 ? 13 GLN D N 1 ATOM 8212 C CA . GLN D 4 32 ? -79.027 56.576 -29.272 1.00 164.80 ? 13 GLN D CA 1 ATOM 8213 C C . GLN D 4 32 ? -79.095 55.552 -28.137 1.00 165.13 ? 13 GLN D C 1 ATOM 8214 O O . GLN D 4 32 ? -79.030 54.347 -28.391 1.00 162.48 ? 13 GLN D O 1 ATOM 8215 C CB . GLN D 4 32 ? -80.424 56.815 -29.866 1.00 159.08 ? 13 GLN D CB 1 ATOM 8216 C CG . GLN D 4 32 ? -81.407 57.552 -28.961 1.00 153.76 ? 13 GLN D CG 1 ATOM 8217 C CD . GLN D 4 32 ? -80.988 58.983 -28.687 1.00 147.67 ? 13 GLN D CD 1 ATOM 8218 O OE1 . GLN D 4 32 ? -80.211 59.569 -29.441 1.00 140.01 ? 13 GLN D OE1 1 ATOM 8219 N NE2 . GLN D 4 32 ? -81.489 59.550 -27.596 1.00 150.47 ? 13 GLN D NE2 1 ATOM 8220 N N . PRO D 4 33 ? -79.202 56.033 -26.886 1.00 167.99 ? 14 PRO D N 1 ATOM 8221 C CA . PRO D 4 33 ? -79.283 55.173 -25.704 1.00 167.36 ? 14 PRO D CA 1 ATOM 8222 C C . PRO D 4 33 ? -80.293 54.036 -25.828 1.00 171.37 ? 14 PRO D C 1 ATOM 8223 O O . PRO D 4 33 ? -81.401 54.247 -26.316 1.00 173.60 ? 14 PRO D O 1 ATOM 8224 C CB . PRO D 4 33 ? -79.742 56.149 -24.627 1.00 167.75 ? 14 PRO D CB 1 ATOM 8225 C CG . PRO D 4 33 ? -79.095 57.418 -24.993 1.00 166.86 ? 14 PRO D CG 1 ATOM 8226 C CD . PRO D 4 33 ? -79.027 57.448 -26.509 1.00 165.85 ? 14 PRO D CD 1 ATOM 8227 N N . GLY D 4 34 ? -79.903 52.848 -25.377 1.00 168.34 ? 15 GLY D N 1 ATOM 8228 C CA . GLY D 4 34 ? -80.776 51.692 -25.401 1.00 169.80 ? 15 GLY D CA 1 ATOM 8229 C C . GLY D 4 34 ? -80.945 51.048 -26.765 1.00 170.41 ? 15 GLY D C 1 ATOM 8230 O O . GLY D 4 34 ? -82.065 50.756 -27.183 1.00 166.55 ? 15 GLY D O 1 ATOM 8231 N N . ARG D 4 35 ? -79.836 50.828 -27.465 1.00 170.26 ? 16 ARG D N 1 ATOM 8232 C CA . ARG D 4 35 ? -79.876 50.153 -28.761 1.00 168.56 ? 16 ARG D CA 1 ATOM 8233 C C . ARG D 4 35 ? -78.652 49.264 -28.980 1.00 171.47 ? 16 ARG D C 1 ATOM 8234 O O . ARG D 4 35 ? -77.809 49.129 -28.094 1.00 170.86 ? 16 ARG D O 1 ATOM 8235 C CB . ARG D 4 35 ? -80.024 51.163 -29.885 1.00 161.17 ? 16 ARG D CB 1 ATOM 8236 N N . SER D 4 36 ? -78.557 48.664 -30.165 1.00 172.72 ? 17 SER D N 1 ATOM 8237 C CA . SER D 4 36 ? -77.535 47.650 -30.424 1.00 170.96 ? 17 SER D CA 1 ATOM 8238 C C . SER D 4 36 ? -76.432 48.078 -31.392 1.00 170.37 ? 17 SER D C 1 ATOM 8239 O O . SER D 4 36 ? -76.667 48.843 -32.327 1.00 172.74 ? 17 SER D O 1 ATOM 8240 C CB . SER D 4 36 ? -78.182 46.354 -30.920 1.00 169.62 ? 17 SER D CB 1 ATOM 8241 O OG . SER D 4 36 ? -77.200 45.369 -31.202 1.00 162.48 ? 17 SER D OG 1 ATOM 8242 N N . LEU D 4 37 ? -75.227 47.568 -31.150 1.00 169.33 ? 18 LEU D N 1 ATOM 8243 C CA . LEU D 4 37 ? -74.085 47.782 -32.033 1.00 167.02 ? 18 LEU D CA 1 ATOM 8244 C C . LEU D 4 37 ? -73.217 46.530 -32.110 1.00 163.19 ? 18 LEU D C 1 ATOM 8245 O O . LEU D 4 37 ? -72.952 45.886 -31.094 1.00 164.82 ? 18 LEU D O 1 ATOM 8246 C CB . LEU D 4 37 ? -73.241 48.964 -31.555 1.00 167.61 ? 18 LEU D CB 1 ATOM 8247 C CG . LEU D 4 37 ? -73.620 50.342 -32.097 1.00 166.65 ? 18 LEU D CG 1 ATOM 8248 C CD1 . LEU D 4 37 ? -72.727 51.417 -31.499 1.00 168.51 ? 18 LEU D CD1 1 ATOM 8249 C CD2 . LEU D 4 37 ? -73.537 50.358 -33.616 1.00 153.47 ? 18 LEU D CD2 1 ATOM 8250 N N . ARG D 4 38 ? -72.778 46.188 -33.317 1.00 155.95 ? 19 ARG D N 1 ATOM 8251 C CA . ARG D 4 38 ? -71.905 45.035 -33.509 1.00 151.88 ? 19 ARG D CA 1 ATOM 8252 C C . ARG D 4 38 ? -70.523 45.438 -34.013 1.00 148.25 ? 19 ARG D C 1 ATOM 8253 O O . ARG D 4 38 ? -70.366 45.876 -35.153 1.00 148.97 ? 19 ARG D O 1 ATOM 8254 C CB . ARG D 4 38 ? -72.555 44.022 -34.454 1.00 150.50 ? 19 ARG D CB 1 ATOM 8255 C CG . ARG D 4 38 ? -73.701 43.255 -33.814 1.00 154.53 ? 19 ARG D CG 1 ATOM 8256 C CD . ARG D 4 38 ? -74.639 42.659 -34.849 1.00 152.56 ? 19 ARG D CD 1 ATOM 8257 N NE . ARG D 4 38 ? -75.691 41.858 -34.228 1.00 154.07 ? 19 ARG D NE 1 ATOM 8258 C CZ . ARG D 4 38 ? -76.785 42.364 -33.667 1.00 151.93 ? 19 ARG D CZ 1 ATOM 8259 N NH1 . ARG D 4 38 ? -76.978 43.676 -33.641 1.00 153.11 ? 19 ARG D NH1 1 ATOM 8260 N NH2 . ARG D 4 38 ? -77.688 41.556 -33.126 1.00 146.29 ? 19 ARG D NH2 1 ATOM 8261 N N . LEU D 4 39 ? -69.523 45.283 -33.150 1.00 153.38 ? 20 LEU D N 1 ATOM 8262 C CA . LEU D 4 39 ? -68.146 45.609 -33.494 1.00 159.74 ? 20 LEU D CA 1 ATOM 8263 C C . LEU D 4 39 ? -67.405 44.347 -33.906 1.00 163.76 ? 20 LEU D C 1 ATOM 8264 O O . LEU D 4 39 ? -67.283 43.414 -33.115 1.00 164.58 ? 20 LEU D O 1 ATOM 8265 C CB . LEU D 4 39 ? -67.429 46.236 -32.296 1.00 152.32 ? 20 LEU D CB 1 ATOM 8266 C CG . LEU D 4 39 ? -68.118 47.369 -31.536 1.00 147.72 ? 20 LEU D CG 1 ATOM 8267 C CD1 . LEU D 4 39 ? -67.201 47.924 -30.453 1.00 145.27 ? 20 LEU D CD1 1 ATOM 8268 C CD2 . LEU D 4 39 ? -68.550 48.466 -32.487 1.00 158.45 ? 20 LEU D CD2 1 ATOM 8269 N N . SER D 4 40 ? -66.897 44.315 -35.134 1.00 162.22 ? 21 SER D N 1 ATOM 8270 C CA . SER D 4 40 ? -66.128 43.162 -35.582 1.00 160.89 ? 21 SER D CA 1 ATOM 8271 C C . SER D 4 40 ? -64.634 43.435 -35.453 1.00 165.84 ? 21 SER D C 1 ATOM 8272 O O . SER D 4 40 ? -64.224 44.545 -35.114 1.00 165.65 ? 21 SER D O 1 ATOM 8273 C CB . SER D 4 40 ? -66.473 42.824 -37.034 1.00 154.15 ? 21 SER D CB 1 ATOM 8274 O OG . SER D 4 40 ? -65.745 41.694 -37.484 1.00 154.31 ? 21 SER D OG 1 ATOM 8275 N N . CYS D 4 41 ? -63.825 42.417 -35.722 1.00 166.08 ? 22 CYS D N 1 ATOM 8276 C CA . CYS D 4 41 ? -62.375 42.566 -35.702 1.00 161.83 ? 22 CYS D CA 1 ATOM 8277 C C . CYS D 4 41 ? -61.744 41.695 -36.781 1.00 159.87 ? 22 CYS D C 1 ATOM 8278 O O . CYS D 4 41 ? -62.074 40.516 -36.903 1.00 154.86 ? 22 CYS D O 1 ATOM 8279 C CB . CYS D 4 41 ? -61.818 42.199 -34.324 1.00 159.00 ? 22 CYS D CB 1 ATOM 8280 S SG . CYS D 4 41 ? -60.130 42.777 -34.001 1.00 167.56 ? 22 CYS D SG 1 ATOM 8281 N N . GLY D 4 42 ? -60.841 42.274 -37.564 1.00 161.17 ? 23 GLY D N 1 ATOM 8282 C CA . GLY D 4 42 ? -60.120 41.515 -38.568 1.00 153.88 ? 23 GLY D CA 1 ATOM 8283 C C . GLY D 4 42 ? -58.822 40.963 -38.012 1.00 147.01 ? 23 GLY D C 1 ATOM 8284 O O . GLY D 4 42 ? -58.256 41.523 -37.074 1.00 146.94 ? 23 GLY D O 1 ATOM 8285 N N . ALA D 4 43 ? -58.348 39.864 -38.589 1.00 137.69 ? 24 ALA D N 1 ATOM 8286 C CA . ALA D 4 43 ? -57.091 39.260 -38.160 1.00 134.50 ? 24 ALA D CA 1 ATOM 8287 C C . ALA D 4 43 ? -56.095 39.199 -39.312 1.00 139.14 ? 24 ALA D C 1 ATOM 8288 O O . ALA D 4 43 ? -56.408 38.687 -40.386 1.00 142.83 ? 24 ALA D O 1 ATOM 8289 C CB . ALA D 4 43 ? -57.334 37.872 -37.591 1.00 131.16 ? 24 ALA D CB 1 ATOM 8290 N N . SER D 4 44 ? -54.894 39.719 -39.082 1.00 137.90 ? 25 SER D N 1 ATOM 8291 C CA . SER D 4 44 ? -53.877 39.767 -40.127 1.00 137.17 ? 25 SER D CA 1 ATOM 8292 C C . SER D 4 44 ? -52.684 38.865 -39.821 1.00 131.66 ? 25 SER D C 1 ATOM 8293 O O . SER D 4 44 ? -51.922 39.121 -38.889 1.00 126.71 ? 25 SER D O 1 ATOM 8294 C CB . SER D 4 44 ? -53.394 41.203 -40.340 1.00 141.94 ? 25 SER D CB 1 ATOM 8295 O OG . SER D 4 44 ? -54.480 42.100 -40.487 1.00 138.54 ? 25 SER D OG 1 ATOM 8296 N N . GLY D 4 45 ? -52.532 37.806 -40.611 1.00 131.02 ? 26 GLY D N 1 ATOM 8297 C CA . GLY D 4 45 ? -51.372 36.938 -40.516 1.00 125.16 ? 26 GLY D CA 1 ATOM 8298 C C . GLY D 4 45 ? -51.481 35.884 -39.433 1.00 121.87 ? 26 GLY D C 1 ATOM 8299 O O . GLY D 4 45 ? -50.755 34.890 -39.447 1.00 125.30 ? 26 GLY D O 1 ATOM 8300 N N . PHE D 4 46 ? -52.397 36.095 -38.495 1.00 125.09 ? 27 PHE D N 1 ATOM 8301 C CA . PHE D 4 46 ? -52.565 35.178 -37.377 1.00 128.26 ? 27 PHE D CA 1 ATOM 8302 C C . PHE D 4 46 ? -53.654 34.152 -37.663 1.00 126.81 ? 27 PHE D C 1 ATOM 8303 O O . PHE D 4 46 ? -54.692 34.481 -38.238 1.00 130.30 ? 27 PHE D O 1 ATOM 8304 C CB . PHE D 4 46 ? -52.890 35.951 -36.109 1.00 128.77 ? 27 PHE D CB 1 ATOM 8305 N N . THR D 4 47 ? -53.416 32.909 -37.260 1.00 119.98 ? 28 THR D N 1 ATOM 8306 C CA . THR D 4 47 ? -54.442 31.880 -37.351 1.00 121.09 ? 28 THR D CA 1 ATOM 8307 C C . THR D 4 47 ? -55.414 32.061 -36.190 1.00 129.52 ? 28 THR D C 1 ATOM 8308 O O . THR D 4 47 ? -55.019 32.012 -35.026 1.00 132.55 ? 28 THR D O 1 ATOM 8309 C CB . THR D 4 47 ? -53.834 30.465 -37.319 1.00 110.25 ? 28 THR D CB 1 ATOM 8310 O OG1 . THR D 4 47 ? -52.681 30.458 -36.468 1.00 102.14 ? 28 THR D OG1 1 ATOM 8311 C CG2 . THR D 4 47 ? -53.416 30.033 -38.715 1.00 105.54 ? 28 THR D CG2 1 ATOM 8312 N N . PHE D 4 48 ? -56.685 32.276 -36.514 1.00 128.86 ? 29 PHE D N 1 ATOM 8313 C CA . PHE D 4 48 ? -57.687 32.618 -35.508 1.00 127.91 ? 29 PHE D CA 1 ATOM 8314 C C . PHE D 4 48 ? -58.049 31.437 -34.611 1.00 130.06 ? 29 PHE D C 1 ATOM 8315 O O . PHE D 4 48 ? -58.511 31.622 -33.485 1.00 137.03 ? 29 PHE D O 1 ATOM 8316 C CB . PHE D 4 48 ? -58.947 33.169 -36.182 1.00 128.79 ? 29 PHE D CB 1 ATOM 8317 C CG . PHE D 4 48 ? -59.976 33.686 -35.217 1.00 127.89 ? 29 PHE D CG 1 ATOM 8318 C CD1 . PHE D 4 48 ? -59.894 34.978 -34.725 1.00 125.03 ? 29 PHE D CD1 1 ATOM 8319 C CD2 . PHE D 4 48 ? -61.029 32.883 -34.808 1.00 129.12 ? 29 PHE D CD2 1 ATOM 8320 C CE1 . PHE D 4 48 ? -60.837 35.458 -33.839 1.00 135.77 ? 29 PHE D CE1 1 ATOM 8321 C CE2 . PHE D 4 48 ? -61.974 33.357 -33.920 1.00 135.89 ? 29 PHE D CE2 1 ATOM 8322 C CZ . PHE D 4 48 ? -61.877 34.647 -33.436 1.00 143.20 ? 29 PHE D CZ 1 ATOM 8323 N N . ASN D 4 49 ? -57.818 30.227 -35.105 1.00 124.42 ? 30 ASN D N 1 ATOM 8324 C CA . ASN D 4 49 ? -58.264 29.022 -34.415 1.00 120.04 ? 30 ASN D CA 1 ATOM 8325 C C . ASN D 4 49 ? -57.321 28.606 -33.290 1.00 118.63 ? 30 ASN D C 1 ATOM 8326 O O . ASN D 4 49 ? -57.565 27.612 -32.606 1.00 118.96 ? 30 ASN D O 1 ATOM 8327 C CB . ASN D 4 49 ? -58.443 27.882 -35.408 1.00 107.23 ? 30 ASN D CB 1 ATOM 8328 N N . THR D 4 50 ? -56.248 29.368 -33.098 1.00 115.09 ? 31 THR D N 1 ATOM 8329 C CA . THR D 4 50 ? -55.236 29.029 -32.101 1.00 116.32 ? 31 THR D CA 1 ATOM 8330 C C . THR D 4 50 ? -55.516 29.600 -30.710 1.00 114.35 ? 31 THR D C 1 ATOM 8331 O O . THR D 4 50 ? -55.776 28.849 -29.772 1.00 115.22 ? 31 THR D O 1 ATOM 8332 C CB . THR D 4 50 ? -53.831 29.474 -32.546 1.00 124.01 ? 31 THR D CB 1 ATOM 8333 O OG1 . THR D 4 50 ? -53.817 30.894 -32.739 1.00 131.45 ? 31 THR D OG1 1 ATOM 8334 C CG2 . THR D 4 50 ? -53.439 28.782 -33.842 1.00 128.03 ? 31 THR D CG2 1 ATOM 8335 N N . TYR D 4 51 ? -55.465 30.924 -30.576 1.00 117.05 ? 32 TYR D N 1 ATOM 8336 C CA . TYR D 4 51 ? -55.554 31.548 -29.254 1.00 120.25 ? 32 TYR D CA 1 ATOM 8337 C C . TYR D 4 51 ? -56.810 32.383 -28.999 1.00 124.27 ? 32 TYR D C 1 ATOM 8338 O O . TYR D 4 51 ? -57.448 32.882 -29.927 1.00 127.41 ? 32 TYR D O 1 ATOM 8339 C CB . TYR D 4 51 ? -54.298 32.371 -28.933 1.00 118.75 ? 32 TYR D CB 1 ATOM 8340 C CG . TYR D 4 51 ? -53.602 32.972 -30.134 1.00 121.93 ? 32 TYR D CG 1 ATOM 8341 C CD1 . TYR D 4 51 ? -54.210 33.960 -30.897 1.00 122.97 ? 32 TYR D CD1 1 ATOM 8342 C CD2 . TYR D 4 51 ? -52.323 32.564 -30.488 1.00 118.32 ? 32 TYR D CD2 1 ATOM 8343 C CE1 . TYR D 4 51 ? -53.567 34.513 -31.992 1.00 125.89 ? 32 TYR D CE1 1 ATOM 8344 C CE2 . TYR D 4 51 ? -51.674 33.111 -31.578 1.00 120.49 ? 32 TYR D CE2 1 ATOM 8345 C CZ . TYR D 4 51 ? -52.300 34.084 -32.326 1.00 126.98 ? 32 TYR D CZ 1 ATOM 8346 O OH . TYR D 4 51 ? -51.653 34.629 -33.411 1.00 124.36 ? 32 TYR D OH 1 ATOM 8347 N N . ALA D 4 52 ? -57.147 32.520 -27.719 1.00 114.65 ? 33 ALA D N 1 ATOM 8348 C CA . ALA D 4 52 ? -58.337 33.242 -27.279 1.00 112.22 ? 33 ALA D CA 1 ATOM 8349 C C . ALA D 4 52 ? -58.246 34.738 -27.569 1.00 118.48 ? 33 ALA D C 1 ATOM 8350 O O . ALA D 4 52 ? -57.156 35.279 -27.755 1.00 116.45 ? 33 ALA D O 1 ATOM 8351 C CB . ALA D 4 52 ? -58.565 33.006 -25.796 1.00 108.03 ? 33 ALA D CB 1 ATOM 8352 N N . MET D 4 53 ? -59.399 35.403 -27.602 1.00 120.64 ? 34 MET D N 1 ATOM 8353 C CA . MET D 4 53 ? -59.458 36.825 -27.933 1.00 123.78 ? 34 MET D CA 1 ATOM 8354 C C . MET D 4 53 ? -60.031 37.669 -26.793 1.00 119.03 ? 34 MET D C 1 ATOM 8355 O O . MET D 4 53 ? -60.980 37.264 -26.126 1.00 112.04 ? 34 MET D O 1 ATOM 8356 C CB . MET D 4 53 ? -60.289 37.039 -29.200 1.00 119.62 ? 34 MET D CB 1 ATOM 8357 C CG . MET D 4 53 ? -59.774 36.289 -30.418 1.00 117.49 ? 34 MET D CG 1 ATOM 8358 S SD . MET D 4 53 ? -58.105 36.778 -30.896 1.00 115.58 ? 34 MET D SD 1 ATOM 8359 C CE . MET D 4 53 ? -58.343 38.517 -31.254 1.00 113.34 ? 34 MET D CE 1 ATOM 8360 N N . HIS D 4 54 ? -59.451 38.848 -26.584 1.00 122.66 ? 35 HIS D N 1 ATOM 8361 C CA . HIS D 4 54 ? -59.926 39.776 -25.561 1.00 116.52 ? 35 HIS D CA 1 ATOM 8362 C C . HIS D 4 54 ? -60.668 40.959 -26.179 1.00 126.90 ? 35 HIS D C 1 ATOM 8363 O O . HIS D 4 54 ? -60.317 41.424 -27.263 1.00 137.31 ? 35 HIS D O 1 ATOM 8364 C CB . HIS D 4 54 ? -58.748 40.327 -24.748 1.00 109.53 ? 35 HIS D CB 1 ATOM 8365 C CG . HIS D 4 54 ? -58.172 39.357 -23.764 1.00 105.36 ? 35 HIS D CG 1 ATOM 8366 N ND1 . HIS D 4 54 ? -58.945 38.470 -23.046 1.00 101.38 ? 35 HIS D ND1 1 ATOM 8367 C CD2 . HIS D 4 54 ? -56.894 39.146 -23.369 1.00 109.52 ? 35 HIS D CD2 1 ATOM 8368 C CE1 . HIS D 4 54 ? -58.167 37.752 -22.256 1.00 106.00 ? 35 HIS D CE1 1 ATOM 8369 N NE2 . HIS D 4 54 ? -56.918 38.141 -22.433 1.00 101.15 ? 35 HIS D NE2 1 ATOM 8370 N N . TRP D 4 55 ? -61.699 41.437 -25.489 1.00 124.82 ? 36 TRP D N 1 ATOM 8371 C CA . TRP D 4 55 ? -62.227 42.774 -25.738 1.00 123.05 ? 36 TRP D CA 1 ATOM 8372 C C . TRP D 4 55 ? -61.848 43.626 -24.535 1.00 119.43 ? 36 TRP D C 1 ATOM 8373 O O . TRP D 4 55 ? -62.163 43.277 -23.399 1.00 122.86 ? 36 TRP D O 1 ATOM 8374 C CB . TRP D 4 55 ? -63.748 42.767 -25.921 1.00 127.22 ? 36 TRP D CB 1 ATOM 8375 C CG . TRP D 4 55 ? -64.212 42.473 -27.323 1.00 135.65 ? 36 TRP D CG 1 ATOM 8376 C CD1 . TRP D 4 55 ? -64.799 41.328 -27.763 1.00 138.60 ? 36 TRP D CD1 1 ATOM 8377 C CD2 . TRP D 4 55 ? -64.135 43.343 -28.461 1.00 142.04 ? 36 TRP D CD2 1 ATOM 8378 N NE1 . TRP D 4 55 ? -65.094 41.423 -29.101 1.00 144.48 ? 36 TRP D NE1 1 ATOM 8379 C CE2 . TRP D 4 55 ? -64.694 42.651 -29.555 1.00 146.07 ? 36 TRP D CE2 1 ATOM 8380 C CE3 . TRP D 4 55 ? -63.646 44.637 -28.662 1.00 144.88 ? 36 TRP D CE3 1 ATOM 8381 C CZ2 . TRP D 4 55 ? -64.777 43.209 -30.829 1.00 149.60 ? 36 TRP D CZ2 1 ATOM 8382 C CZ3 . TRP D 4 55 ? -63.729 45.189 -29.928 1.00 147.67 ? 36 TRP D CZ3 1 ATOM 8383 C CH2 . TRP D 4 55 ? -64.290 44.476 -30.994 1.00 150.02 ? 36 TRP D CH2 1 ATOM 8384 N N . VAL D 4 56 ? -61.151 44.728 -24.778 1.00 120.65 ? 37 VAL D N 1 ATOM 8385 C CA . VAL D 4 56 ? -60.698 45.583 -23.687 1.00 124.20 ? 37 VAL D CA 1 ATOM 8386 C C . VAL D 4 56 ? -61.143 47.030 -23.891 1.00 135.95 ? 37 VAL D C 1 ATOM 8387 O O . VAL D 4 56 ? -60.912 47.620 -24.947 1.00 142.71 ? 37 VAL D O 1 ATOM 8388 C CB . VAL D 4 56 ? -59.170 45.502 -23.497 1.00 119.49 ? 37 VAL D CB 1 ATOM 8389 C CG1 . VAL D 4 56 ? -58.693 46.604 -22.587 1.00 113.57 ? 37 VAL D CG1 1 ATOM 8390 C CG2 . VAL D 4 56 ? -58.777 44.142 -22.935 1.00 116.31 ? 37 VAL D CG2 1 ATOM 8391 N N . ARG D 4 57 ? -61.784 47.589 -22.869 1.00 142.89 ? 38 ARG D N 1 ATOM 8392 C CA . ARG D 4 57 ? -62.407 48.904 -22.967 1.00 150.98 ? 38 ARG D CA 1 ATOM 8393 C C . ARG D 4 57 ? -61.628 49.989 -22.224 1.00 153.24 ? 38 ARG D C 1 ATOM 8394 O O . ARG D 4 57 ? -61.126 49.766 -21.122 1.00 147.02 ? 38 ARG D O 1 ATOM 8395 C CB . ARG D 4 57 ? -63.844 48.834 -22.438 1.00 148.72 ? 38 ARG D CB 1 ATOM 8396 C CG . ARG D 4 57 ? -64.594 50.154 -22.459 1.00 149.19 ? 38 ARG D CG 1 ATOM 8397 C CD . ARG D 4 57 ? -66.023 49.989 -21.966 1.00 145.75 ? 38 ARG D CD 1 ATOM 8398 N NE . ARG D 4 57 ? -66.076 49.457 -20.607 1.00 147.44 ? 38 ARG D NE 1 ATOM 8399 C CZ . ARG D 4 57 ? -66.185 50.205 -19.514 1.00 143.59 ? 38 ARG D CZ 1 ATOM 8400 N NH1 . ARG D 4 57 ? -66.258 51.525 -19.613 1.00 148.30 ? 38 ARG D NH1 1 ATOM 8401 N NH2 . ARG D 4 57 ? -66.225 49.631 -18.320 1.00 134.40 ? 38 ARG D NH2 1 ATOM 8402 N N . GLN D 4 58 ? -61.528 51.162 -22.844 1.00 160.36 ? 39 GLN D N 1 ATOM 8403 C CA . GLN D 4 58 ? -60.957 52.336 -22.194 1.00 166.26 ? 39 GLN D CA 1 ATOM 8404 C C . GLN D 4 58 ? -61.837 53.559 -22.437 1.00 175.87 ? 39 GLN D C 1 ATOM 8405 O O . GLN D 4 58 ? -62.051 53.961 -23.581 1.00 173.05 ? 39 GLN D O 1 ATOM 8406 C CB . GLN D 4 58 ? -59.538 52.613 -22.697 1.00 169.47 ? 39 GLN D CB 1 ATOM 8407 C CG . GLN D 4 58 ? -58.904 53.851 -22.075 1.00 172.70 ? 39 GLN D CG 1 ATOM 8408 C CD . GLN D 4 58 ? -57.535 54.170 -22.645 1.00 175.37 ? 39 GLN D CD 1 ATOM 8409 O OE1 . GLN D 4 58 ? -56.725 54.841 -22.003 1.00 171.33 ? 39 GLN D OE1 1 ATOM 8410 N NE2 . GLN D 4 58 ? -57.271 53.699 -23.859 1.00 173.18 ? 39 GLN D NE2 1 ATOM 8411 N N . ALA D 4 59 ? -62.344 54.144 -21.358 1.00 182.22 ? 40 ALA D N 1 ATOM 8412 C CA . ALA D 4 59 ? -63.157 55.351 -21.451 1.00 178.16 ? 40 ALA D CA 1 ATOM 8413 C C . ALA D 4 59 ? -62.257 56.582 -21.500 1.00 175.57 ? 40 ALA D C 1 ATOM 8414 O O . ALA D 4 59 ? -61.168 56.575 -20.922 1.00 169.33 ? 40 ALA D O 1 ATOM 8415 C CB . ALA D 4 59 ? -64.124 55.431 -20.281 1.00 169.35 ? 40 ALA D CB 1 ATOM 8416 N N . PRO D 4 60 ? -62.702 57.640 -22.201 1.00 175.45 ? 41 PRO D N 1 ATOM 8417 C CA . PRO D 4 60 ? -61.884 58.849 -22.354 1.00 170.23 ? 41 PRO D CA 1 ATOM 8418 C C . PRO D 4 60 ? -61.497 59.455 -21.010 1.00 162.45 ? 41 PRO D C 1 ATOM 8419 O O . PRO D 4 60 ? -62.362 59.704 -20.170 1.00 160.80 ? 41 PRO D O 1 ATOM 8420 C CB . PRO D 4 60 ? -62.816 59.805 -23.104 1.00 167.32 ? 41 PRO D CB 1 ATOM 8421 C CG . PRO D 4 60 ? -63.747 58.915 -23.846 1.00 161.19 ? 41 PRO D CG 1 ATOM 8422 C CD . PRO D 4 60 ? -63.965 57.728 -22.956 1.00 169.20 ? 41 PRO D CD 1 ATOM 8423 N N . GLY D 4 61 ? -60.203 59.692 -20.819 1.00 162.01 ? 42 GLY D N 1 ATOM 8424 C CA . GLY D 4 61 ? -59.701 60.240 -19.573 1.00 164.25 ? 42 GLY D CA 1 ATOM 8425 C C . GLY D 4 61 ? -59.571 59.190 -18.485 1.00 164.46 ? 42 GLY D C 1 ATOM 8426 O O . GLY D 4 61 ? -58.899 59.408 -17.477 1.00 157.82 ? 42 GLY D O 1 ATOM 8427 N N . LYS D 4 62 ? -60.212 58.043 -18.695 1.00 166.89 ? 43 LYS D N 1 ATOM 8428 C CA . LYS D 4 62 ? -60.214 56.966 -17.712 1.00 169.89 ? 43 LYS D CA 1 ATOM 8429 C C . LYS D 4 62 ? -59.151 55.917 -18.015 1.00 175.09 ? 43 LYS D C 1 ATOM 8430 O O . LYS D 4 62 ? -58.349 56.077 -18.934 1.00 178.74 ? 43 LYS D O 1 ATOM 8431 C CB . LYS D 4 62 ? -61.593 56.307 -17.633 1.00 165.95 ? 43 LYS D CB 1 ATOM 8432 C CG . LYS D 4 62 ? -62.701 57.229 -17.146 1.00 161.94 ? 43 LYS D CG 1 ATOM 8433 C CD . LYS D 4 62 ? -63.984 56.455 -16.881 1.00 151.19 ? 43 LYS D CD 1 ATOM 8434 C CE . LYS D 4 62 ? -65.127 57.384 -16.508 1.00 141.14 ? 43 LYS D CE 1 ATOM 8435 N NZ . LYS D 4 62 ? -66.402 56.640 -16.311 1.00 149.48 ? 43 LYS D NZ 1 ATOM 8436 N N . GLY D 4 63 ? -59.156 54.842 -17.234 1.00 177.30 ? 44 GLY D N 1 ATOM 8437 C CA . GLY D 4 63 ? -58.154 53.803 -17.361 1.00 175.22 ? 44 GLY D CA 1 ATOM 8438 C C . GLY D 4 63 ? -58.570 52.630 -18.226 1.00 168.02 ? 44 GLY D C 1 ATOM 8439 O O . GLY D 4 63 ? -59.463 52.740 -19.066 1.00 159.19 ? 44 GLY D O 1 ATOM 8440 N N . VAL D 4 64 ? -57.914 51.496 -18.007 1.00 165.14 ? 45 VAL D N 1 ATOM 8441 C CA . VAL D 4 64 ? -58.142 50.304 -18.809 1.00 155.09 ? 45 VAL D CA 1 ATOM 8442 C C . VAL D 4 64 ? -58.957 49.277 -18.029 1.00 147.14 ? 45 VAL D C 1 ATOM 8443 O O . VAL D 4 64 ? -58.659 48.987 -16.872 1.00 144.60 ? 45 VAL D O 1 ATOM 8444 C CB . VAL D 4 64 ? -56.806 49.679 -19.242 1.00 148.45 ? 45 VAL D CB 1 ATOM 8445 C CG1 . VAL D 4 64 ? -57.022 48.713 -20.378 1.00 143.39 ? 45 VAL D CG1 1 ATOM 8446 C CG2 . VAL D 4 64 ? -55.838 50.765 -19.668 1.00 153.28 ? 45 VAL D CG2 1 ATOM 8447 N N . GLU D 4 65 ? -59.993 48.738 -18.665 1.00 142.69 ? 46 GLU D N 1 ATOM 8448 C CA . GLU D 4 65 ? -60.853 47.744 -18.032 1.00 140.08 ? 46 GLU D CA 1 ATOM 8449 C C . GLU D 4 65 ? -61.129 46.580 -18.980 1.00 135.51 ? 46 GLU D C 1 ATOM 8450 O O . GLU D 4 65 ? -61.684 46.777 -20.061 1.00 136.45 ? 46 GLU D O 1 ATOM 8451 C CB . GLU D 4 65 ? -62.177 48.384 -17.595 1.00 142.89 ? 46 GLU D CB 1 ATOM 8452 C CG . GLU D 4 65 ? -62.028 49.549 -16.623 1.00 144.22 ? 46 GLU D CG 1 ATOM 8453 C CD . GLU D 4 65 ? -63.332 50.291 -16.384 1.00 133.29 ? 46 GLU D CD 1 ATOM 8454 O OE1 . GLU D 4 65 ? -64.347 49.938 -17.018 1.00 124.52 ? 46 GLU D OE1 1 ATOM 8455 O OE2 . GLU D 4 65 ? -63.339 51.231 -15.560 1.00 133.29 ? 46 GLU D OE2 1 ATOM 8456 N N . TRP D 4 66 ? -60.741 45.373 -18.578 1.00 126.78 ? 47 TRP D N 1 ATOM 8457 C CA . TRP D 4 66 ? -61.028 44.184 -19.377 1.00 123.77 ? 47 TRP D CA 1 ATOM 8458 C C . TRP D 4 66 ? -62.536 43.949 -19.461 1.00 118.28 ? 47 TRP D C 1 ATOM 8459 O O . TRP D 4 66 ? -63.279 44.314 -18.550 1.00 114.28 ? 47 TRP D O 1 ATOM 8460 C CB . TRP D 4 66 ? -60.322 42.946 -18.806 1.00 117.90 ? 47 TRP D CB 1 ATOM 8461 C CG . TRP D 4 66 ? -60.865 41.660 -19.345 1.00 117.03 ? 47 TRP D CG 1 ATOM 8462 C CD1 . TRP D 4 66 ? -60.583 41.097 -20.556 1.00 114.31 ? 47 TRP D CD1 1 ATOM 8463 C CD2 . TRP D 4 66 ? -61.803 40.786 -18.708 1.00 119.96 ? 47 TRP D CD2 1 ATOM 8464 N NE1 . TRP D 4 66 ? -61.281 39.923 -20.711 1.00 112.12 ? 47 TRP D NE1 1 ATOM 8465 C CE2 . TRP D 4 66 ? -62.038 39.710 -19.588 1.00 113.28 ? 47 TRP D CE2 1 ATOM 8466 C CE3 . TRP D 4 66 ? -62.466 40.805 -17.478 1.00 121.18 ? 47 TRP D CE3 1 ATOM 8467 C CZ2 . TRP D 4 66 ? -62.909 38.666 -19.272 1.00 109.26 ? 47 TRP D CZ2 1 ATOM 8468 C CZ3 . TRP D 4 66 ? -63.326 39.766 -17.169 1.00 114.90 ? 47 TRP D CZ3 1 ATOM 8469 C CH2 . TRP D 4 66 ? -63.539 38.714 -18.059 1.00 109.46 ? 47 TRP D CH2 1 ATOM 8470 N N . VAL D 4 67 ? -62.981 43.344 -20.560 1.00 114.37 ? 48 VAL D N 1 ATOM 8471 C CA . VAL D 4 67 ? -64.399 43.076 -20.770 1.00 113.83 ? 48 VAL D CA 1 ATOM 8472 C C . VAL D 4 67 ? -64.717 41.592 -20.977 1.00 118.81 ? 48 VAL D C 1 ATOM 8473 O O . VAL D 4 67 ? -65.403 40.984 -20.159 1.00 122.94 ? 48 VAL D O 1 ATOM 8474 C CB . VAL D 4 67 ? -64.957 43.891 -21.950 1.00 118.79 ? 48 VAL D CB 1 ATOM 8475 C CG1 . VAL D 4 67 ? -66.377 43.453 -22.275 1.00 116.95 ? 48 VAL D CG1 1 ATOM 8476 C CG2 . VAL D 4 67 ? -64.906 45.374 -21.634 1.00 121.38 ? 48 VAL D CG2 1 ATOM 8477 N N . ALA D 4 68 ? -64.229 41.006 -22.066 1.00 117.01 ? 49 ALA D N 1 ATOM 8478 C CA . ALA D 4 68 ? -64.612 39.634 -22.395 1.00 112.85 ? 49 ALA D CA 1 ATOM 8479 C C . ALA D 4 68 ? -63.517 38.807 -23.067 1.00 109.18 ? 49 ALA D C 1 ATOM 8480 O O . ALA D 4 68 ? -62.653 39.342 -23.759 1.00 116.70 ? 49 ALA D O 1 ATOM 8481 C CB . ALA D 4 68 ? -65.868 39.636 -23.253 1.00 115.77 ? 49 ALA D CB 1 ATOM 8482 N N . VAL D 4 69 ? -63.572 37.494 -22.850 1.00 106.39 ? 50 VAL D N 1 ATOM 8483 C CA . VAL D 4 69 ? -62.670 36.547 -23.496 1.00 109.32 ? 50 VAL D CA 1 ATOM 8484 C C . VAL D 4 69 ? -63.490 35.505 -24.241 1.00 109.23 ? 50 VAL D C 1 ATOM 8485 O O . VAL D 4 69 ? -64.432 34.956 -23.685 1.00 107.47 ? 50 VAL D O 1 ATOM 8486 C CB . VAL D 4 69 ? -61.818 35.781 -22.463 1.00 97.86 ? 50 VAL D CB 1 ATOM 8487 C CG1 . VAL D 4 69 ? -60.716 34.990 -23.152 1.00 91.85 ? 50 VAL D CG1 1 ATOM 8488 C CG2 . VAL D 4 69 ? -61.229 36.729 -21.457 1.00 100.68 ? 50 VAL D CG2 1 ATOM 8489 N N . VAL D 4 70 ? -63.140 35.226 -25.491 1.00 105.42 ? 51 VAL D N 1 ATOM 8490 C CA . VAL D 4 70 ? -63.732 34.092 -26.191 1.00 99.80 ? 51 VAL D CA 1 ATOM 8491 C C . VAL D 4 70 ? -62.716 32.964 -26.251 1.00 105.40 ? 51 VAL D C 1 ATOM 8492 O O . VAL D 4 70 ? -61.584 33.170 -26.680 1.00 108.39 ? 51 VAL D O 1 ATOM 8493 C CB . VAL D 4 70 ? -64.171 34.454 -27.621 1.00 108.35 ? 51 VAL D CB 1 ATOM 8494 C CG1 . VAL D 4 70 ? -64.662 33.217 -28.357 1.00 110.61 ? 51 VAL D CG1 1 ATOM 8495 C CG2 . VAL D 4 70 ? -65.257 35.497 -27.588 1.00 118.30 ? 51 VAL D CG2 1 ATOM 8496 N N . SER D 4 71 ? -63.125 31.772 -25.825 1.00 105.02 ? 52 SER D N 1 ATOM 8497 C CA . SER D 4 71 ? -62.263 30.594 -25.872 1.00 103.98 ? 52 SER D CA 1 ATOM 8498 C C . SER D 4 71 ? -62.000 30.245 -27.326 1.00 109.43 ? 52 SER D C 1 ATOM 8499 O O . SER D 4 71 ? -62.691 30.740 -28.212 1.00 112.88 ? 52 SER D O 1 ATOM 8500 C CB . SER D 4 71 ? -62.909 29.405 -25.165 1.00 103.04 ? 52 SER D CB 1 ATOM 8501 O OG . SER D 4 71 ? -64.008 28.897 -25.900 1.00 97.74 ? 52 SER D OG 1 ATOM 8502 N N . ASP D 4 72 ? -60.984 29.424 -27.568 1.00 108.72 ? 53 ASP D N 1 ATOM 8503 C CA . ASP D 4 72 ? -60.594 29.051 -28.922 1.00 104.16 ? 53 ASP D CA 1 ATOM 8504 C C . ASP D 4 72 ? -61.794 28.564 -29.736 1.00 110.62 ? 53 ASP D C 1 ATOM 8505 O O . ASP D 4 72 ? -62.554 27.703 -29.290 1.00 110.76 ? 53 ASP D O 1 ATOM 8506 C CB . ASP D 4 72 ? -59.524 27.961 -28.856 1.00 98.64 ? 53 ASP D CB 1 ATOM 8507 C CG . ASP D 4 72 ? -58.665 28.065 -27.608 1.00 101.39 ? 53 ASP D CG 1 ATOM 8508 O OD1 . ASP D 4 72 ? -58.235 29.187 -27.271 1.00 104.23 ? 53 ASP D OD1 1 ATOM 8509 O OD2 . ASP D 4 72 ? -58.436 27.025 -26.954 1.00 95.27 ? 53 ASP D OD2 1 ATOM 8510 N N . GLY D 4 73 ? -61.963 29.138 -30.925 1.00 119.26 ? 54 GLY D N 1 ATOM 8511 C CA . GLY D 4 73 ? -63.117 28.855 -31.761 1.00 128.74 ? 54 GLY D CA 1 ATOM 8512 C C . GLY D 4 73 ? -64.402 29.330 -31.111 1.00 123.10 ? 54 GLY D C 1 ATOM 8513 O O . GLY D 4 73 ? -64.370 30.112 -30.165 1.00 116.54 ? 54 GLY D O 1 ATOM 8514 N N . GLY D 4 74 ? -65.541 28.879 -31.625 1.00 125.19 ? 55 GLY D N 1 ATOM 8515 C CA . GLY D 4 74 ? -66.801 29.137 -30.956 1.00 121.19 ? 55 GLY D CA 1 ATOM 8516 C C . GLY D 4 74 ? -66.805 28.365 -29.654 1.00 120.63 ? 55 GLY D C 1 ATOM 8517 O O . GLY D 4 74 ? -66.620 27.147 -29.657 1.00 120.80 ? 55 GLY D O 1 ATOM 8518 N N . GLY D 4 75 ? -67.011 29.057 -28.538 1.00 120.04 ? 56 GLY D N 1 ATOM 8519 C CA . GLY D 4 75 ? -66.955 28.399 -27.245 1.00 115.08 ? 56 GLY D CA 1 ATOM 8520 C C . GLY D 4 75 ? -67.235 29.267 -26.034 1.00 110.63 ? 56 GLY D C 1 ATOM 8521 O O . GLY D 4 75 ? -67.616 30.432 -26.159 1.00 114.65 ? 56 GLY D O 1 ATOM 8522 N N . ASN D 4 76 ? -67.039 28.685 -24.855 1.00 101.08 ? 57 ASN D N 1 ATOM 8523 C CA . ASN D 4 76 ? -67.359 29.346 -23.600 1.00 97.25 ? 57 ASN D CA 1 ATOM 8524 C C . ASN D 4 76 ? -66.601 30.644 -23.405 1.00 95.14 ? 57 ASN D C 1 ATOM 8525 O O . ASN D 4 76 ? -65.375 30.675 -23.458 1.00 99.97 ? 57 ASN D O 1 ATOM 8526 C CB . ASN D 4 76 ? -67.087 28.405 -22.430 1.00 94.50 ? 57 ASN D CB 1 ATOM 8527 C CG . ASN D 4 76 ? -67.782 27.082 -22.587 1.00 100.03 ? 57 ASN D CG 1 ATOM 8528 O OD1 . ASN D 4 76 ? -68.905 27.024 -23.081 1.00 101.97 ? 57 ASN D OD1 1 ATOM 8529 N ND2 . ASN D 4 76 ? -67.114 26.005 -22.189 1.00 90.55 ? 57 ASN D ND2 1 ATOM 8530 N N . ARG D 4 77 ? -67.349 31.713 -23.164 1.00 96.55 ? 58 ARG D N 1 ATOM 8531 C CA . ARG D 4 77 ? -66.768 33.039 -23.068 1.00 94.49 ? 58 ARG D CA 1 ATOM 8532 C C . ARG D 4 77 ? -66.957 33.631 -21.679 1.00 101.68 ? 58 ARG D C 1 ATOM 8533 O O . ARG D 4 77 ? -68.069 33.649 -21.153 1.00 112.49 ? 58 ARG D O 1 ATOM 8534 C CB . ARG D 4 77 ? -67.374 33.947 -24.115 1.00 98.19 ? 58 ARG D CB 1 ATOM 8535 N N . TYR D 4 78 ? -65.871 34.121 -21.091 1.00 98.37 ? 59 TYR D N 1 ATOM 8536 C CA . TYR D 4 78 ? -65.938 34.731 -19.768 1.00 96.64 ? 59 TYR D CA 1 ATOM 8537 C C . TYR D 4 78 ? -66.299 36.212 -19.872 1.00 107.75 ? 59 TYR D C 1 ATOM 8538 O O . TYR D 4 78 ? -65.666 36.962 -20.615 1.00 112.25 ? 59 TYR D O 1 ATOM 8539 C CB . TYR D 4 78 ? -64.617 34.544 -19.014 1.00 87.53 ? 59 TYR D CB 1 ATOM 8540 C CG . TYR D 4 78 ? -64.436 33.170 -18.399 1.00 83.55 ? 59 TYR D CG 1 ATOM 8541 C CD1 . TYR D 4 78 ? -65.084 32.057 -18.919 1.00 85.29 ? 59 TYR D CD1 1 ATOM 8542 C CD2 . TYR D 4 78 ? -63.631 32.991 -17.284 1.00 80.48 ? 59 TYR D CD2 1 ATOM 8543 C CE1 . TYR D 4 78 ? -64.922 30.806 -18.352 1.00 85.51 ? 59 TYR D CE1 1 ATOM 8544 C CE2 . TYR D 4 78 ? -63.464 31.748 -16.711 1.00 81.81 ? 59 TYR D CE2 1 ATOM 8545 C CZ . TYR D 4 78 ? -64.113 30.658 -17.246 1.00 82.45 ? 59 TYR D CZ 1 ATOM 8546 O OH . TYR D 4 78 ? -63.945 29.418 -16.675 1.00 80.52 ? 59 TYR D OH 1 ATOM 8547 N N . TYR D 4 79 ? -67.327 36.624 -19.134 1.00 111.59 ? 60 TYR D N 1 ATOM 8548 C CA . TYR D 4 79 ? -67.794 38.008 -19.161 1.00 107.98 ? 60 TYR D CA 1 ATOM 8549 C C . TYR D 4 79 ? -67.402 38.770 -17.897 1.00 108.74 ? 60 TYR D C 1 ATOM 8550 O O . TYR D 4 79 ? -67.387 38.210 -16.801 1.00 111.70 ? 60 TYR D O 1 ATOM 8551 C CB . TYR D 4 79 ? -69.314 38.065 -19.341 1.00 110.30 ? 60 TYR D CB 1 ATOM 8552 C CG . TYR D 4 79 ? -69.785 37.911 -20.770 1.00 114.02 ? 60 TYR D CG 1 ATOM 8553 C CD1 . TYR D 4 79 ? -69.590 38.925 -21.697 1.00 116.47 ? 60 TYR D CD1 1 ATOM 8554 C CD2 . TYR D 4 79 ? -70.446 36.762 -21.187 1.00 116.51 ? 60 TYR D CD2 1 ATOM 8555 C CE1 . TYR D 4 79 ? -70.024 38.796 -23.001 1.00 124.55 ? 60 TYR D CE1 1 ATOM 8556 C CE2 . TYR D 4 79 ? -70.885 36.624 -22.490 1.00 120.13 ? 60 TYR D CE2 1 ATOM 8557 C CZ . TYR D 4 79 ? -70.671 37.645 -23.391 1.00 126.30 ? 60 TYR D CZ 1 ATOM 8558 O OH . TYR D 4 79 ? -71.106 37.518 -24.687 1.00 134.69 ? 60 TYR D OH 1 ATOM 8559 N N . ALA D 4 80 ? -67.088 40.052 -18.061 1.00 110.83 ? 61 ALA D N 1 ATOM 8560 C CA . ALA D 4 80 ? -66.741 40.917 -16.935 1.00 116.90 ? 61 ALA D CA 1 ATOM 8561 C C . ALA D 4 80 ? -67.969 41.277 -16.109 1.00 122.43 ? 61 ALA D C 1 ATOM 8562 O O . ALA D 4 80 ? -69.101 41.126 -16.566 1.00 124.76 ? 61 ALA D O 1 ATOM 8563 C CB . ALA D 4 80 ? -66.038 42.177 -17.412 1.00 117.59 ? 61 ALA D CB 1 ATOM 8564 N N . ALA D 4 81 ? -67.725 41.744 -14.888 1.00 122.53 ? 62 ALA D N 1 ATOM 8565 C CA . ALA D 4 81 ? -68.777 42.080 -13.930 1.00 123.99 ? 62 ALA D CA 1 ATOM 8566 C C . ALA D 4 81 ? -69.873 43.002 -14.474 1.00 126.81 ? 62 ALA D C 1 ATOM 8567 O O . ALA D 4 81 ? -71.031 42.597 -14.582 1.00 131.20 ? 62 ALA D O 1 ATOM 8568 C CB . ALA D 4 81 ? -68.163 42.680 -12.669 1.00 113.12 ? 62 ALA D CB 1 ATOM 8569 N N . SER D 4 82 ? -69.498 44.233 -14.810 1.00 120.37 ? 63 SER D N 1 ATOM 8570 C CA . SER D 4 82 ? -70.457 45.286 -15.152 1.00 121.35 ? 63 SER D CA 1 ATOM 8571 C C . SER D 4 82 ? -71.475 44.932 -16.239 1.00 128.12 ? 63 SER D C 1 ATOM 8572 O O . SER D 4 82 ? -72.670 45.176 -16.083 1.00 134.11 ? 63 SER D O 1 ATOM 8573 C CB . SER D 4 82 ? -69.707 46.561 -15.556 1.00 110.45 ? 63 SER D CB 1 ATOM 8574 O OG . SER D 4 82 ? -68.964 46.350 -16.751 1.00 105.07 ? 63 SER D OG 1 ATOM 8575 N N . VAL D 4 83 ? -70.991 44.371 -17.340 1.00 125.52 ? 64 VAL D N 1 ATOM 8576 C CA . VAL D 4 83 ? -71.810 44.168 -18.536 1.00 133.25 ? 64 VAL D CA 1 ATOM 8577 C C . VAL D 4 83 ? -72.455 42.788 -18.719 1.00 133.21 ? 64 VAL D C 1 ATOM 8578 O O . VAL D 4 83 ? -73.024 42.510 -19.773 1.00 133.88 ? 64 VAL D O 1 ATOM 8579 C CB . VAL D 4 83 ? -71.038 44.565 -19.809 1.00 135.82 ? 64 VAL D CB 1 ATOM 8580 C CG1 . VAL D 4 83 ? -71.361 46.001 -20.187 1.00 141.62 ? 64 VAL D CG1 1 ATOM 8581 C CG2 . VAL D 4 83 ? -69.543 44.378 -19.593 1.00 124.08 ? 64 VAL D CG2 1 ATOM 8582 N N . LYS D 4 84 ? -72.354 41.935 -17.702 1.00 129.09 ? 65 LYS D N 1 ATOM 8583 C CA . LYS D 4 84 ? -72.710 40.514 -17.814 1.00 123.40 ? 65 LYS D CA 1 ATOM 8584 C C . LYS D 4 84 ? -74.059 40.213 -18.478 1.00 125.26 ? 65 LYS D C 1 ATOM 8585 O O . LYS D 4 84 ? -74.195 39.213 -19.183 1.00 123.51 ? 65 LYS D O 1 ATOM 8586 C CB . LYS D 4 84 ? -72.644 39.845 -16.442 1.00 114.97 ? 65 LYS D CB 1 ATOM 8587 N N . GLY D 4 85 ? -75.052 41.068 -18.255 1.00 128.10 ? 66 GLY D N 1 ATOM 8588 C CA . GLY D 4 85 ? -76.357 40.870 -18.860 1.00 132.21 ? 66 GLY D CA 1 ATOM 8589 C C . GLY D 4 85 ? -76.536 41.505 -20.228 1.00 133.89 ? 66 GLY D C 1 ATOM 8590 O O . GLY D 4 85 ? -77.331 41.030 -21.039 1.00 140.62 ? 66 GLY D O 1 ATOM 8591 N N . ARG D 4 86 ? -75.798 42.578 -20.489 1.00 130.64 ? 67 ARG D N 1 ATOM 8592 C CA . ARG D 4 86 ? -76.017 43.375 -21.694 1.00 139.67 ? 67 ARG D CA 1 ATOM 8593 C C . ARG D 4 86 ? -75.103 43.020 -22.866 1.00 148.81 ? 67 ARG D C 1 ATOM 8594 O O . ARG D 4 86 ? -75.246 43.582 -23.954 1.00 151.19 ? 67 ARG D O 1 ATOM 8595 C CB . ARG D 4 86 ? -75.898 44.855 -21.367 1.00 140.55 ? 67 ARG D CB 1 ATOM 8596 N N . PHE D 4 87 ? -74.173 42.094 -22.658 1.00 146.71 ? 68 PHE D N 1 ATOM 8597 C CA . PHE D 4 87 ? -73.190 41.782 -23.696 1.00 139.71 ? 68 PHE D CA 1 ATOM 8598 C C . PHE D 4 87 ? -73.351 40.421 -24.363 1.00 140.76 ? 68 PHE D C 1 ATOM 8599 O O . PHE D 4 87 ? -73.600 39.415 -23.705 1.00 142.15 ? 68 PHE D O 1 ATOM 8600 C CB . PHE D 4 87 ? -71.759 41.938 -23.162 1.00 137.19 ? 68 PHE D CB 1 ATOM 8601 C CG . PHE D 4 87 ? -71.228 43.333 -23.257 1.00 141.26 ? 68 PHE D CG 1 ATOM 8602 C CD1 . PHE D 4 87 ? -72.068 44.383 -23.578 1.00 136.89 ? 68 PHE D CD1 1 ATOM 8603 C CD2 . PHE D 4 87 ? -69.885 43.594 -23.047 1.00 148.56 ? 68 PHE D CD2 1 ATOM 8604 C CE1 . PHE D 4 87 ? -71.587 45.671 -23.669 1.00 134.26 ? 68 PHE D CE1 1 ATOM 8605 C CE2 . PHE D 4 87 ? -69.398 44.886 -23.140 1.00 143.90 ? 68 PHE D CE2 1 ATOM 8606 C CZ . PHE D 4 87 ? -70.248 45.921 -23.454 1.00 137.83 ? 68 PHE D CZ 1 ATOM 8607 N N . THR D 4 88 ? -73.195 40.419 -25.683 1.00 145.99 ? 69 THR D N 1 ATOM 8608 C CA . THR D 4 88 ? -73.218 39.196 -26.468 1.00 151.59 ? 69 THR D CA 1 ATOM 8609 C C . THR D 4 88 ? -71.929 39.105 -27.278 1.00 151.32 ? 69 THR D C 1 ATOM 8610 O O . THR D 4 88 ? -71.631 39.991 -28.082 1.00 153.80 ? 69 THR D O 1 ATOM 8611 C CB . THR D 4 88 ? -74.424 39.153 -27.428 1.00 153.12 ? 69 THR D CB 1 ATOM 8612 O OG1 . THR D 4 88 ? -75.630 39.423 -26.705 1.00 141.85 ? 69 THR D OG1 1 ATOM 8613 C CG2 . THR D 4 88 ? -74.531 37.792 -28.097 1.00 151.30 ? 69 THR D CG2 1 ATOM 8614 N N . ILE D 4 89 ? -71.161 38.041 -27.060 1.00 148.09 ? 70 ILE D N 1 ATOM 8615 C CA . ILE D 4 89 ? -69.899 37.860 -27.771 1.00 146.10 ? 70 ILE D CA 1 ATOM 8616 C C . ILE D 4 89 ? -69.870 36.522 -28.517 1.00 148.11 ? 70 ILE D C 1 ATOM 8617 O O . ILE D 4 89 ? -70.322 35.495 -28.006 1.00 149.59 ? 70 ILE D O 1 ATOM 8618 C CB . ILE D 4 89 ? -68.684 38.017 -26.818 1.00 133.89 ? 70 ILE D CB 1 ATOM 8619 C CG1 . ILE D 4 89 ? -67.438 38.464 -27.573 1.00 128.29 ? 70 ILE D CG1 1 ATOM 8620 C CG2 . ILE D 4 89 ? -68.405 36.742 -26.044 1.00 132.15 ? 70 ILE D CG2 1 ATOM 8621 C CD1 . ILE D 4 89 ? -66.262 38.675 -26.659 1.00 117.44 ? 70 ILE D CD1 1 ATOM 8622 N N . SER D 4 90 ? -69.375 36.553 -29.748 1.00 148.05 ? 71 SER D N 1 ATOM 8623 C CA . SER D 4 90 ? -69.263 35.347 -30.558 1.00 146.75 ? 71 SER D CA 1 ATOM 8624 C C . SER D 4 90 ? -68.130 35.480 -31.564 1.00 143.68 ? 71 SER D C 1 ATOM 8625 O O . SER D 4 90 ? -67.831 36.579 -32.032 1.00 149.48 ? 71 SER D O 1 ATOM 8626 C CB . SER D 4 90 ? -70.581 35.054 -31.282 1.00 156.74 ? 71 SER D CB 1 ATOM 8627 O OG . SER D 4 90 ? -70.974 36.144 -32.097 1.00 160.07 ? 71 SER D OG 1 ATOM 8628 N N . ARG D 4 91 ? -67.498 34.359 -31.890 1.00 140.02 ? 72 ARG D N 1 ATOM 8629 C CA . ARG D 4 91 ? -66.429 34.356 -32.878 1.00 148.42 ? 72 ARG D CA 1 ATOM 8630 C C . ARG D 4 91 ? -66.342 33.014 -33.599 1.00 149.09 ? 72 ARG D C 1 ATOM 8631 O O . ARG D 4 91 ? -66.610 31.965 -33.010 1.00 147.16 ? 72 ARG D O 1 ATOM 8632 C CB . ARG D 4 91 ? -65.103 34.693 -32.217 1.00 140.74 ? 72 ARG D CB 1 ATOM 8633 N N . ASP D 4 92 ? -65.968 33.054 -34.875 1.00 149.00 ? 73 ASP D N 1 ATOM 8634 C CA . ASP D 4 92 ? -65.756 31.836 -35.652 1.00 144.53 ? 73 ASP D CA 1 ATOM 8635 C C . ASP D 4 92 ? -64.430 31.903 -36.406 1.00 143.94 ? 73 ASP D C 1 ATOM 8636 O O . ASP D 4 92 ? -63.891 32.986 -36.633 1.00 144.89 ? 73 ASP D O 1 ATOM 8637 C CB . ASP D 4 92 ? -66.925 31.576 -36.611 1.00 135.96 ? 73 ASP D CB 1 ATOM 8638 C CG . ASP D 4 92 ? -66.932 32.516 -37.801 1.00 130.56 ? 73 ASP D CG 1 ATOM 8639 O OD1 . ASP D 4 92 ? -66.568 33.699 -37.639 1.00 131.69 ? 73 ASP D OD1 1 ATOM 8640 O OD2 . ASP D 4 92 ? -67.306 32.068 -38.905 1.00 129.82 ? 73 ASP D OD2 1 ATOM 8641 N N . ASN D 4 93 ? -63.906 30.743 -36.790 1.00 143.68 ? 74 ASN D N 1 ATOM 8642 C CA . ASN D 4 93 ? -62.580 30.666 -37.396 1.00 144.09 ? 74 ASN D CA 1 ATOM 8643 C C . ASN D 4 93 ? -62.613 30.794 -38.918 1.00 140.80 ? 74 ASN D C 1 ATOM 8644 O O . ASN D 4 93 ? -61.582 30.669 -39.579 1.00 133.44 ? 74 ASN D O 1 ATOM 8645 C CB . ASN D 4 93 ? -61.879 29.378 -36.981 1.00 144.38 ? 74 ASN D CB 1 ATOM 8646 N N . SER D 4 94 ? -63.796 31.044 -39.471 1.00 142.95 ? 75 SER D N 1 ATOM 8647 C CA . SER D 4 94 ? -63.946 31.145 -40.918 1.00 138.63 ? 75 SER D CA 1 ATOM 8648 C C . SER D 4 94 ? -63.380 32.456 -41.454 1.00 135.32 ? 75 SER D C 1 ATOM 8649 O O . SER D 4 94 ? -62.360 32.468 -42.141 1.00 141.76 ? 75 SER D O 1 ATOM 8650 C CB . SER D 4 94 ? -65.420 31.025 -41.314 1.00 133.37 ? 75 SER D CB 1 ATOM 8651 O OG . SER D 4 94 ? -65.994 29.834 -40.805 1.00 139.11 ? 75 SER D OG 1 ATOM 8652 N N . LYS D 4 95 ? -64.049 33.558 -41.132 1.00 129.77 ? 76 LYS D N 1 ATOM 8653 C CA . LYS D 4 95 ? -63.671 34.872 -41.642 1.00 130.71 ? 76 LYS D CA 1 ATOM 8654 C C . LYS D 4 95 ? -62.760 35.648 -40.692 1.00 136.93 ? 76 LYS D C 1 ATOM 8655 O O . LYS D 4 95 ? -62.486 36.827 -40.922 1.00 142.22 ? 76 LYS D O 1 ATOM 8656 C CB . LYS D 4 95 ? -64.911 35.686 -41.982 1.00 125.13 ? 76 LYS D CB 1 ATOM 8657 N N . ASN D 4 96 ? -62.323 34.989 -39.619 1.00 135.94 ? 77 ASN D N 1 ATOM 8658 C CA . ASN D 4 96 ? -61.566 35.626 -38.539 1.00 138.92 ? 77 ASN D CA 1 ATOM 8659 C C . ASN D 4 96 ? -62.399 36.698 -37.848 1.00 146.52 ? 77 ASN D C 1 ATOM 8660 O O . ASN D 4 96 ? -61.870 37.702 -37.369 1.00 145.04 ? 77 ASN D O 1 ATOM 8661 C CB . ASN D 4 96 ? -60.242 36.218 -39.036 1.00 132.79 ? 77 ASN D CB 1 ATOM 8662 C CG . ASN D 4 96 ? -59.373 35.198 -39.740 1.00 133.11 ? 77 ASN D CG 1 ATOM 8663 O OD1 . ASN D 4 96 ? -58.605 34.474 -39.106 1.00 134.81 ? 77 ASN D OD1 1 ATOM 8664 N ND2 . ASN D 4 96 ? -59.481 35.142 -41.062 1.00 132.44 ? 77 ASN D ND2 1 ATOM 8665 N N . THR D 4 97 ? -63.706 36.470 -37.796 1.00 156.06 ? 78 THR D N 1 ATOM 8666 C CA . THR D 4 97 ? -64.636 37.446 -37.245 1.00 160.62 ? 78 THR D CA 1 ATOM 8667 C C . THR D 4 97 ? -64.924 37.209 -35.769 1.00 156.95 ? 78 THR D C 1 ATOM 8668 O O . THR D 4 97 ? -65.518 36.198 -35.395 1.00 151.92 ? 78 THR D O 1 ATOM 8669 C CB . THR D 4 97 ? -65.977 37.440 -38.007 1.00 158.98 ? 78 THR D CB 1 ATOM 8670 O OG1 . THR D 4 97 ? -66.465 36.096 -38.113 1.00 152.51 ? 78 THR D OG1 1 ATOM 8671 C CG2 . THR D 4 97 ? -65.807 38.026 -39.400 1.00 151.48 ? 78 THR D CG2 1 ATOM 8672 N N . LEU D 4 98 ? -64.494 38.148 -34.935 1.00 157.50 ? 79 LEU D N 1 ATOM 8673 C CA . LEU D 4 98 ? -64.894 38.164 -33.537 1.00 157.36 ? 79 LEU D CA 1 ATOM 8674 C C . LEU D 4 98 ? -65.752 39.399 -33.312 1.00 164.04 ? 79 LEU D C 1 ATOM 8675 O O . LEU D 4 98 ? -65.244 40.520 -33.314 1.00 165.14 ? 79 LEU D O 1 ATOM 8676 C CB . LEU D 4 98 ? -63.675 38.192 -32.635 1.00 142.11 ? 79 LEU D CB 1 ATOM 8677 N N . PHE D 4 99 ? -67.052 39.198 -33.119 1.00 160.65 ? 80 PHE D N 1 ATOM 8678 C CA . PHE D 4 99 ? -67.951 40.328 -32.945 1.00 160.33 ? 80 PHE D CA 1 ATOM 8679 C C . PHE D 4 99 ? -68.146 40.660 -31.472 1.00 155.68 ? 80 PHE D C 1 ATOM 8680 O O . PHE D 4 99 ? -67.686 39.934 -30.589 1.00 145.99 ? 80 PHE D O 1 ATOM 8681 C CB . PHE D 4 99 ? -69.318 40.027 -33.570 1.00 163.12 ? 80 PHE D CB 1 ATOM 8682 C CG . PHE D 4 99 ? -69.324 40.036 -35.075 1.00 163.61 ? 80 PHE D CG 1 ATOM 8683 C CD1 . PHE D 4 99 ? -69.588 41.204 -35.773 1.00 164.75 ? 80 PHE D CD1 1 ATOM 8684 C CD2 . PHE D 4 99 ? -69.090 38.874 -35.792 1.00 162.65 ? 80 PHE D CD2 1 ATOM 8685 C CE1 . PHE D 4 99 ? -69.605 41.216 -37.156 1.00 167.42 ? 80 PHE D CE1 1 ATOM 8686 C CE2 . PHE D 4 99 ? -69.106 38.880 -37.177 1.00 166.25 ? 80 PHE D CE2 1 ATOM 8687 C CZ . PHE D 4 99 ? -69.363 40.053 -37.858 1.00 165.71 ? 80 PHE D CZ 1 ATOM 8688 N N . LEU D 4 100 ? -68.838 41.765 -31.219 1.00 162.44 ? 81 LEU D N 1 ATOM 8689 C CA . LEU D 4 100 ? -69.350 42.084 -29.893 1.00 159.01 ? 81 LEU D CA 1 ATOM 8690 C C . LEU D 4 100 ? -70.705 42.764 -30.044 1.00 157.75 ? 81 LEU D C 1 ATOM 8691 O O . LEU D 4 100 ? -70.830 43.749 -30.770 1.00 160.04 ? 81 LEU D O 1 ATOM 8692 C CB . LEU D 4 100 ? -68.376 42.981 -29.126 1.00 150.97 ? 81 LEU D CB 1 ATOM 8693 C CG . LEU D 4 100 ? -68.819 43.424 -27.729 1.00 145.55 ? 81 LEU D CG 1 ATOM 8694 C CD1 . LEU D 4 100 ? -69.287 42.233 -26.906 1.00 145.21 ? 81 LEU D CD1 1 ATOM 8695 C CD2 . LEU D 4 100 ? -67.691 44.154 -27.018 1.00 138.12 ? 81 LEU D CD2 1 ATOM 8696 N N . GLN D 4 101 ? -71.717 42.249 -29.358 1.00 152.95 ? 82 GLN D N 1 ATOM 8697 C CA . GLN D 4 101 ? -73.035 42.861 -29.418 1.00 154.96 ? 82 GLN D CA 1 ATOM 8698 C C . GLN D 4 101 ? -73.437 43.458 -28.080 1.00 160.94 ? 82 GLN D C 1 ATOM 8699 O O . GLN D 4 101 ? -73.519 42.750 -27.072 1.00 162.82 ? 82 GLN D O 1 ATOM 8700 C CB . GLN D 4 101 ? -74.095 41.858 -29.881 1.00 154.22 ? 82 GLN D CB 1 ATOM 8701 C CG . GLN D 4 101 ? -75.510 42.422 -29.846 1.00 156.87 ? 82 GLN D CG 1 ATOM 8702 C CD . GLN D 4 101 ? -76.572 41.371 -30.101 1.00 157.32 ? 82 GLN D CD 1 ATOM 8703 O OE1 . GLN D 4 101 ? -76.275 40.268 -30.556 1.00 158.19 ? 82 GLN D OE1 1 ATOM 8704 N NE2 . GLN D 4 101 ? -77.822 41.710 -29.802 1.00 156.89 ? 82 GLN D NE2 1 ATOM 8705 N N . LEU D 4 102 ? -73.685 44.762 -28.076 1.00 163.05 ? 83 LEU D N 1 ATOM 8706 C CA . LEU D 4 102 ? -74.223 45.421 -26.899 1.00 164.29 ? 83 LEU D CA 1 ATOM 8707 C C . LEU D 4 102 ? -75.703 45.624 -27.174 1.00 165.33 ? 83 LEU D C 1 ATOM 8708 O O . LEU D 4 102 ? -76.079 46.492 -27.957 1.00 170.06 ? 83 LEU D O 1 ATOM 8709 C CB . LEU D 4 102 ? -73.567 46.798 -26.709 1.00 162.65 ? 83 LEU D CB 1 ATOM 8710 C CG . LEU D 4 102 ? -72.034 46.995 -26.780 1.00 149.31 ? 83 LEU D CG 1 ATOM 8711 C CD1 . LEU D 4 102 ? -71.510 47.021 -28.210 1.00 146.30 ? 83 LEU D CD1 1 ATOM 8712 C CD2 . LEU D 4 102 ? -71.647 48.271 -26.048 1.00 148.15 ? 83 LEU D CD2 1 ATOM 8713 N N . ASN D 4 103 ? -76.551 44.837 -26.526 1.00 157.98 ? 84 ASN D N 1 ATOM 8714 C CA . ASN D 4 103 ? -77.982 44.895 -26.810 1.00 163.03 ? 84 ASN D CA 1 ATOM 8715 C C . ASN D 4 103 ? -78.715 46.018 -26.080 1.00 167.72 ? 84 ASN D C 1 ATOM 8716 O O . ASN D 4 103 ? -79.624 46.636 -26.635 1.00 169.01 ? 84 ASN D O 1 ATOM 8717 C CB . ASN D 4 103 ? -78.658 43.544 -26.540 1.00 166.52 ? 84 ASN D CB 1 ATOM 8718 C CG . ASN D 4 103 ? -79.756 43.229 -27.545 1.00 166.58 ? 84 ASN D CG 1 ATOM 8719 O OD1 . ASN D 4 103 ? -79.705 43.668 -28.696 1.00 162.09 ? 84 ASN D OD1 1 ATOM 8720 N ND2 . ASN D 4 103 ? -80.754 42.467 -27.114 1.00 166.84 ? 84 ASN D ND2 1 ATOM 8721 N N . THR D 4 104 ? -78.313 46.286 -24.840 1.00 166.27 ? 85 THR D N 1 ATOM 8722 C CA . THR D 4 104 ? -79.092 47.174 -23.979 1.00 166.83 ? 85 THR D CA 1 ATOM 8723 C C . THR D 4 104 ? -78.383 48.414 -23.419 1.00 164.27 ? 85 THR D C 1 ATOM 8724 O O . THR D 4 104 ? -78.786 49.533 -23.735 1.00 166.31 ? 85 THR D O 1 ATOM 8725 C CB . THR D 4 104 ? -79.782 46.403 -22.828 1.00 158.75 ? 85 THR D CB 1 ATOM 8726 O OG1 . THR D 4 104 ? -78.846 45.511 -22.214 1.00 158.75 ? 85 THR D OG1 1 ATOM 8727 C CG2 . THR D 4 104 ? -80.960 45.599 -23.356 1.00 149.64 ? 85 THR D CG2 1 ATOM 8728 N N . LEU D 4 105 ? -77.346 48.224 -22.598 1.00 160.51 ? 86 LEU D N 1 ATOM 8729 C CA . LEU D 4 105 ? -76.881 49.302 -21.714 1.00 161.25 ? 86 LEU D CA 1 ATOM 8730 C C . LEU D 4 105 ? -76.547 50.595 -22.452 1.00 164.11 ? 86 LEU D C 1 ATOM 8731 O O . LEU D 4 105 ? -75.672 50.637 -23.317 1.00 159.48 ? 86 LEU D O 1 ATOM 8732 C CB . LEU D 4 105 ? -75.654 48.848 -20.918 1.00 161.67 ? 86 LEU D CB 1 ATOM 8733 C CG . LEU D 4 105 ? -75.876 47.999 -19.667 1.00 151.11 ? 86 LEU D CG 1 ATOM 8734 C CD1 . LEU D 4 105 ? -74.542 47.624 -19.034 1.00 134.33 ? 86 LEU D CD1 1 ATOM 8735 C CD2 . LEU D 4 105 ? -76.758 48.732 -18.671 1.00 149.75 ? 86 LEU D CD2 1 ATOM 8736 N N . ARG D 4 106 ? -77.288 51.640 -22.101 1.00 169.32 ? 87 ARG D N 1 ATOM 8737 C CA . ARG D 4 106 ? -77.148 52.958 -22.714 1.00 170.96 ? 87 ARG D CA 1 ATOM 8738 C C . ARG D 4 106 ? -76.014 53.900 -22.273 1.00 172.11 ? 87 ARG D C 1 ATOM 8739 O O . ARG D 4 106 ? -75.127 54.224 -23.063 1.00 166.63 ? 87 ARG D O 1 ATOM 8740 C CB . ARG D 4 106 ? -78.479 53.685 -22.603 1.00 166.90 ? 87 ARG D CB 1 ATOM 8741 N N . PRO D 4 107 ? -76.050 54.336 -20.999 1.00 173.97 ? 88 PRO D N 1 ATOM 8742 C CA . PRO D 4 107 ? -75.357 55.584 -20.650 1.00 171.27 ? 88 PRO D CA 1 ATOM 8743 C C . PRO D 4 107 ? -73.833 55.561 -20.533 1.00 162.50 ? 88 PRO D C 1 ATOM 8744 O O . PRO D 4 107 ? -73.148 56.421 -21.088 1.00 157.95 ? 88 PRO D O 1 ATOM 8745 C CB . PRO D 4 107 ? -75.978 55.950 -19.296 1.00 169.16 ? 88 PRO D CB 1 ATOM 8746 C CG . PRO D 4 107 ? -76.492 54.643 -18.722 1.00 166.16 ? 88 PRO D CG 1 ATOM 8747 C CD . PRO D 4 107 ? -76.433 53.581 -19.792 1.00 166.15 ? 88 PRO D CD 1 ATOM 8748 N N . GLU D 4 108 ? -73.323 54.567 -19.817 1.00 162.27 ? 89 GLU D N 1 ATOM 8749 C CA . GLU D 4 108 ? -71.952 54.593 -19.321 1.00 166.97 ? 89 GLU D CA 1 ATOM 8750 C C . GLU D 4 108 ? -71.000 53.792 -20.196 1.00 166.31 ? 89 GLU D C 1 ATOM 8751 O O . GLU D 4 108 ? -69.812 53.669 -19.899 1.00 158.47 ? 89 GLU D O 1 ATOM 8752 C CB . GLU D 4 108 ? -71.928 54.097 -17.875 1.00 167.50 ? 89 GLU D CB 1 ATOM 8753 C CG . GLU D 4 108 ? -72.968 54.789 -16.999 1.00 163.38 ? 89 GLU D CG 1 ATOM 8754 C CD . GLU D 4 108 ? -73.269 54.032 -15.721 1.00 170.25 ? 89 GLU D CD 1 ATOM 8755 O OE1 . GLU D 4 108 ? -72.486 53.127 -15.366 1.00 170.12 ? 89 GLU D OE1 1 ATOM 8756 O OE2 . GLU D 4 108 ? -74.293 54.340 -15.074 1.00 174.74 ? 89 GLU D OE2 1 ATOM 8757 N N . ASP D 4 109 ? -71.539 53.254 -21.282 1.00 166.93 ? 90 ASP D N 1 ATOM 8758 C CA . ASP D 4 109 ? -70.796 52.356 -22.151 1.00 166.56 ? 90 ASP D CA 1 ATOM 8759 C C . ASP D 4 109 ? -70.051 53.125 -23.233 1.00 173.10 ? 90 ASP D C 1 ATOM 8760 O O . ASP D 4 109 ? -69.451 52.528 -24.127 1.00 172.75 ? 90 ASP D O 1 ATOM 8761 C CB . ASP D 4 109 ? -71.744 51.332 -22.770 1.00 165.57 ? 90 ASP D CB 1 ATOM 8762 C CG . ASP D 4 109 ? -72.726 50.774 -21.761 1.00 162.22 ? 90 ASP D CG 1 ATOM 8763 O OD1 . ASP D 4 109 ? -73.745 51.446 -21.496 1.00 164.91 ? 90 ASP D OD1 1 ATOM 8764 O OD2 . ASP D 4 109 ? -72.476 49.674 -21.225 1.00 152.00 ? 90 ASP D OD2 1 ATOM 8765 N N . THR D 4 110 ? -70.088 54.452 -23.148 1.00 177.56 ? 91 THR D N 1 ATOM 8766 C CA . THR D 4 110 ? -69.395 55.282 -24.120 1.00 180.67 ? 91 THR D CA 1 ATOM 8767 C C . THR D 4 110 ? -67.911 55.266 -23.786 1.00 179.01 ? 91 THR D C 1 ATOM 8768 O O . THR D 4 110 ? -67.496 55.732 -22.723 1.00 173.38 ? 91 THR D O 1 ATOM 8769 C CB . THR D 4 110 ? -69.893 56.739 -24.066 1.00 181.57 ? 91 THR D CB 1 ATOM 8770 O OG1 . THR D 4 110 ? -71.318 56.769 -24.216 1.00 172.72 ? 91 THR D OG1 1 ATOM 8771 C CG2 . THR D 4 110 ? -69.249 57.568 -25.167 1.00 176.69 ? 91 THR D CG2 1 ATOM 8772 N N . ALA D 4 111 ? -67.119 54.737 -24.714 1.00 179.71 ? 92 ALA D N 1 ATOM 8773 C CA . ALA D 4 111 ? -65.697 54.514 -24.489 1.00 178.17 ? 92 ALA D CA 1 ATOM 8774 C C . ALA D 4 111 ? -65.012 54.095 -25.784 1.00 178.38 ? 92 ALA D C 1 ATOM 8775 O O . ALA D 4 111 ? -65.641 54.044 -26.841 1.00 172.54 ? 92 ALA D O 1 ATOM 8776 C CB . ALA D 4 111 ? -65.495 53.452 -23.424 1.00 171.52 ? 92 ALA D CB 1 ATOM 8777 N N . VAL D 4 112 ? -63.720 53.795 -25.695 1.00 181.24 ? 93 VAL D N 1 ATOM 8778 C CA . VAL D 4 112 ? -62.980 53.244 -26.826 1.00 183.57 ? 93 VAL D CA 1 ATOM 8779 C C . VAL D 4 112 ? -62.737 51.751 -26.608 1.00 177.97 ? 93 VAL D C 1 ATOM 8780 O O . VAL D 4 112 ? -62.188 51.349 -25.582 1.00 170.24 ? 93 VAL D O 1 ATOM 8781 C CB . VAL D 4 112 ? -61.631 53.962 -27.027 1.00 180.88 ? 93 VAL D CB 1 ATOM 8782 C CG1 . VAL D 4 112 ? -60.910 53.408 -28.248 1.00 170.42 ? 93 VAL D CG1 1 ATOM 8783 C CG2 . VAL D 4 112 ? -61.843 55.462 -27.167 1.00 181.31 ? 93 VAL D CG2 1 ATOM 8784 N N . TYR D 4 113 ? -63.151 50.934 -27.572 1.00 176.79 ? 94 TYR D N 1 ATOM 8785 C CA . TYR D 4 113 ? -63.023 49.484 -27.450 1.00 169.26 ? 94 TYR D CA 1 ATOM 8786 C C . TYR D 4 113 ? -61.830 48.937 -28.235 1.00 165.27 ? 94 TYR D C 1 ATOM 8787 O O . TYR D 4 113 ? -61.597 49.324 -29.380 1.00 166.44 ? 94 TYR D O 1 ATOM 8788 C CB . TYR D 4 113 ? -64.317 48.789 -27.892 1.00 164.79 ? 94 TYR D CB 1 ATOM 8789 C CG . TYR D 4 113 ? -65.517 49.108 -27.025 1.00 165.68 ? 94 TYR D CG 1 ATOM 8790 C CD1 . TYR D 4 113 ? -66.334 50.195 -27.307 1.00 170.46 ? 94 TYR D CD1 1 ATOM 8791 C CD2 . TYR D 4 113 ? -65.835 48.319 -25.926 1.00 163.31 ? 94 TYR D CD2 1 ATOM 8792 C CE1 . TYR D 4 113 ? -67.432 50.490 -26.518 1.00 171.75 ? 94 TYR D CE1 1 ATOM 8793 C CE2 . TYR D 4 113 ? -66.931 48.607 -25.132 1.00 164.08 ? 94 TYR D CE2 1 ATOM 8794 C CZ . TYR D 4 113 ? -67.726 49.693 -25.432 1.00 168.70 ? 94 TYR D CZ 1 ATOM 8795 O OH . TYR D 4 113 ? -68.818 49.984 -24.646 1.00 164.90 ? 94 TYR D OH 1 ATOM 8796 N N . TYR D 4 114 ? -61.077 48.039 -27.606 1.00 161.98 ? 95 TYR D N 1 ATOM 8797 C CA . TYR D 4 114 ? -59.923 47.404 -28.238 1.00 155.84 ? 95 TYR D CA 1 ATOM 8798 C C . TYR D 4 114 ? -60.147 45.906 -28.404 1.00 151.36 ? 95 TYR D C 1 ATOM 8799 O O . TYR D 4 114 ? -60.842 45.285 -27.600 1.00 148.95 ? 95 TYR D O 1 ATOM 8800 C CB . TYR D 4 114 ? -58.663 47.620 -27.394 1.00 148.06 ? 95 TYR D CB 1 ATOM 8801 C CG . TYR D 4 114 ? -58.059 49.002 -27.485 1.00 154.04 ? 95 TYR D CG 1 ATOM 8802 C CD1 . TYR D 4 114 ? -57.247 49.355 -28.554 1.00 159.76 ? 95 TYR D CD1 1 ATOM 8803 C CD2 . TYR D 4 114 ? -58.283 49.947 -26.493 1.00 160.32 ? 95 TYR D CD2 1 ATOM 8804 C CE1 . TYR D 4 114 ? -56.687 50.615 -28.640 1.00 164.21 ? 95 TYR D CE1 1 ATOM 8805 C CE2 . TYR D 4 114 ? -57.725 51.210 -26.570 1.00 166.34 ? 95 TYR D CE2 1 ATOM 8806 C CZ . TYR D 4 114 ? -56.927 51.538 -27.646 1.00 167.25 ? 95 TYR D CZ 1 ATOM 8807 O OH . TYR D 4 114 ? -56.368 52.793 -27.729 1.00 168.63 ? 95 TYR D OH 1 ATOM 8808 N N . CYS D 4 115 ? -59.555 45.325 -29.443 1.00 151.31 ? 96 CYS D N 1 ATOM 8809 C CA . CYS D 4 115 ? -59.523 43.871 -29.575 1.00 145.42 ? 96 CYS D CA 1 ATOM 8810 C C . CYS D 4 115 ? -58.085 43.368 -29.461 1.00 137.37 ? 96 CYS D C 1 ATOM 8811 O O . CYS D 4 115 ? -57.197 43.816 -30.187 1.00 143.10 ? 96 CYS D O 1 ATOM 8812 C CB . CYS D 4 115 ? -60.186 43.399 -30.878 1.00 151.47 ? 96 CYS D CB 1 ATOM 8813 S SG . CYS D 4 115 ? -59.288 43.736 -32.416 1.00 160.76 ? 96 CYS D SG 1 ATOM 8814 N N . ALA D 4 116 ? -57.857 42.450 -28.527 1.00 128.64 ? 97 ALA D N 1 ATOM 8815 C CA . ALA D 4 116 ? -56.518 41.931 -28.281 1.00 123.08 ? 97 ALA D CA 1 ATOM 8816 C C . ALA D 4 116 ? -56.534 40.414 -28.156 1.00 117.66 ? 97 ALA D C 1 ATOM 8817 O O . ALA D 4 116 ? -57.573 39.815 -27.880 1.00 121.28 ? 97 ALA D O 1 ATOM 8818 C CB . ALA D 4 116 ? -55.929 42.563 -27.028 1.00 119.55 ? 97 ALA D CB 1 ATOM 8819 N N . ARG D 4 117 ? -55.378 39.794 -28.365 1.00 116.04 ? 98 ARG D N 1 ATOM 8820 C CA . ARG D 4 117 ? -55.264 38.344 -28.278 1.00 111.86 ? 98 ARG D CA 1 ATOM 8821 C C . ARG D 4 117 ? -54.292 37.943 -27.177 1.00 112.35 ? 98 ARG D C 1 ATOM 8822 O O . ARG D 4 117 ? -53.192 38.488 -27.084 1.00 111.72 ? 98 ARG D O 1 ATOM 8823 C CB . ARG D 4 117 ? -54.819 37.769 -29.610 1.00 115.86 ? 98 ARG D CB 1 ATOM 8824 N N . SER D 4 118 ? -54.703 36.987 -26.348 1.00 111.55 ? 99 SER D N 1 ATOM 8825 C CA . SER D 4 118 ? -53.868 36.506 -25.252 1.00 108.76 ? 99 SER D CA 1 ATOM 8826 C C . SER D 4 118 ? -52.570 35.901 -25.777 1.00 104.42 ? 99 SER D C 1 ATOM 8827 O O . SER D 4 118 ? -52.526 35.381 -26.892 1.00 108.80 ? 99 SER D O 1 ATOM 8828 C CB . SER D 4 118 ? -54.629 35.490 -24.393 1.00 109.22 ? 99 SER D CB 1 ATOM 8829 O OG . SER D 4 118 ? -55.189 34.459 -25.187 1.00 106.14 ? 99 SER D OG 1 ATOM 8830 N N . ARG D 4 119 ? -51.516 35.984 -24.969 1.00 103.40 ? 100 ARG D N 1 ATOM 8831 C CA . ARG D 4 119 ? -50.185 35.545 -25.378 1.00 106.74 ? 100 ARG D CA 1 ATOM 8832 C C . ARG D 4 119 ? -50.161 34.066 -25.752 1.00 102.55 ? 100 ARG D C 1 ATOM 8833 O O . ARG D 4 119 ? -49.810 33.704 -26.875 1.00 111.46 ? 100 ARG D O 1 ATOM 8834 C CB . ARG D 4 119 ? -49.184 35.827 -24.259 1.00 102.93 ? 100 ARG D CB 1 ATOM 8835 C CG . ARG D 4 119 ? -47.744 35.546 -24.616 1.00 108.47 ? 100 ARG D CG 1 ATOM 8836 C CD . ARG D 4 119 ? -46.817 36.330 -23.711 1.00 115.99 ? 100 ARG D CD 1 ATOM 8837 N NE . ARG D 4 119 ? -45.426 36.229 -24.132 1.00 127.61 ? 100 ARG D NE 1 ATOM 8838 C CZ . ARG D 4 119 ? -44.904 36.924 -25.136 1.00 137.93 ? 100 ARG D CZ 1 ATOM 8839 N NH1 . ARG D 4 119 ? -45.660 37.767 -25.828 1.00 135.75 ? 100 ARG D NH1 1 ATOM 8840 N NH2 . ARG D 4 119 ? -43.629 36.772 -25.453 1.00 141.38 ? 100 ARG D NH2 1 ATOM 8841 N N . GLY D 4 120 ? -50.536 33.217 -24.803 1.00 86.96 ? 101 GLY D N 1 ATOM 8842 C CA . GLY D 4 120 ? -50.803 31.822 -25.092 1.00 84.02 ? 101 GLY D CA 1 ATOM 8843 C C . GLY D 4 120 ? -52.307 31.667 -25.058 1.00 88.60 ? 101 GLY D C 1 ATOM 8844 O O . GLY D 4 120 ? -53.031 32.633 -25.294 1.00 97.08 ? 101 GLY D O 1 ATOM 8845 N N . ASN D 4 121 ? -52.788 30.465 -24.774 1.00 85.32 ? 102 ASN D N 1 ATOM 8846 C CA . ASN D 4 121 ? -54.205 30.295 -24.491 1.00 88.21 ? 102 ASN D CA 1 ATOM 8847 C C . ASN D 4 121 ? -54.490 30.729 -23.062 1.00 89.27 ? 102 ASN D C 1 ATOM 8848 O O . ASN D 4 121 ? -55.556 31.266 -22.763 1.00 98.14 ? 102 ASN D O 1 ATOM 8849 C CB . ASN D 4 121 ? -54.640 28.845 -24.697 1.00 91.73 ? 102 ASN D CB 1 ATOM 8850 C CG . ASN D 4 121 ? -55.078 28.566 -26.118 1.00 98.08 ? 102 ASN D CG 1 ATOM 8851 O OD1 . ASN D 4 121 ? -55.459 29.476 -26.850 1.00 97.58 ? 102 ASN D OD1 1 ATOM 8852 N ND2 . ASN D 4 121 ? -55.034 27.299 -26.512 1.00 102.63 ? 102 ASN D ND2 1 ATOM 8853 N N . HIS D 4 122 ? -53.514 30.502 -22.189 1.00 82.55 ? 103 HIS D N 1 ATOM 8854 C CA . HIS D 4 122 ? -53.655 30.781 -20.766 1.00 79.47 ? 103 HIS D CA 1 ATOM 8855 C C . HIS D 4 122 ? -53.720 32.276 -20.470 1.00 80.38 ? 103 HIS D C 1 ATOM 8856 O O . HIS D 4 122 ? -53.214 33.094 -21.240 1.00 78.99 ? 103 HIS D O 1 ATOM 8857 C CB . HIS D 4 122 ? -52.508 30.141 -19.986 1.00 80.91 ? 103 HIS D CB 1 ATOM 8858 C CG . HIS D 4 122 ? -52.941 29.476 -18.722 1.00 86.06 ? 103 HIS D CG 1 ATOM 8859 N ND1 . HIS D 4 122 ? -53.626 28.277 -18.706 1.00 88.05 ? 103 HIS D ND1 1 ATOM 8860 C CD2 . HIS D 4 122 ? -52.801 29.842 -17.426 1.00 89.11 ? 103 HIS D CD2 1 ATOM 8861 C CE1 . HIS D 4 122 ? -53.880 27.935 -17.457 1.00 94.73 ? 103 HIS D CE1 1 ATOM 8862 N NE2 . HIS D 4 122 ? -53.389 28.865 -16.661 1.00 94.17 ? 103 HIS D NE2 1 ATOM 8863 N N . TYR D 4 123 ? -54.348 32.625 -19.351 1.00 92.54 ? 104 TYR D N 1 ATOM 8864 C CA . TYR D 4 123 ? -54.556 34.024 -18.990 1.00 97.08 ? 104 TYR D CA 1 ATOM 8865 C C . TYR D 4 123 ? -53.366 34.667 -18.274 1.00 93.99 ? 104 TYR D C 1 ATOM 8866 O O . TYR D 4 123 ? -53.281 35.892 -18.194 1.00 93.25 ? 104 TYR D O 1 ATOM 8867 C CB . TYR D 4 123 ? -55.844 34.196 -18.165 1.00 92.34 ? 104 TYR D CB 1 ATOM 8868 C CG . TYR D 4 123 ? -56.004 33.243 -16.995 1.00 89.18 ? 104 TYR D CG 1 ATOM 8869 C CD1 . TYR D 4 123 ? -55.310 33.437 -15.813 1.00 95.97 ? 104 TYR D CD1 1 ATOM 8870 C CD2 . TYR D 4 123 ? -56.874 32.164 -17.065 1.00 81.16 ? 104 TYR D CD2 1 ATOM 8871 C CE1 . TYR D 4 123 ? -55.465 32.574 -14.738 1.00 94.70 ? 104 TYR D CE1 1 ATOM 8872 C CE2 . TYR D 4 123 ? -57.031 31.295 -15.999 1.00 86.56 ? 104 TYR D CE2 1 ATOM 8873 C CZ . TYR D 4 123 ? -56.324 31.504 -14.838 1.00 88.84 ? 104 TYR D CZ 1 ATOM 8874 O OH . TYR D 4 123 ? -56.476 30.646 -13.771 1.00 83.58 ? 104 TYR D OH 1 ATOM 8875 N N . TYR D 4 124 ? -52.452 33.837 -17.775 1.00 89.11 ? 105 TYR D N 1 ATOM 8876 C CA . TYR D 4 124 ? -51.299 34.298 -17.001 1.00 99.54 ? 105 TYR D CA 1 ATOM 8877 C C . TYR D 4 124 ? -50.507 35.416 -17.685 1.00 100.70 ? 105 TYR D C 1 ATOM 8878 O O . TYR D 4 124 ? -50.042 36.353 -17.036 1.00 104.77 ? 105 TYR D O 1 ATOM 8879 C CB . TYR D 4 124 ? -50.340 33.135 -16.718 1.00 105.51 ? 105 TYR D CB 1 ATOM 8880 C CG . TYR D 4 124 ? -50.876 32.017 -15.846 1.00 106.65 ? 105 TYR D CG 1 ATOM 8881 C CD1 . TYR D 4 124 ? -52.060 32.157 -15.131 1.00 102.35 ? 105 TYR D CD1 1 ATOM 8882 C CD2 . TYR D 4 124 ? -50.181 30.814 -15.731 1.00 109.83 ? 105 TYR D CD2 1 ATOM 8883 C CE1 . TYR D 4 124 ? -52.536 31.123 -14.330 1.00 102.76 ? 105 TYR D CE1 1 ATOM 8884 C CE2 . TYR D 4 124 ? -50.661 29.783 -14.937 1.00 111.10 ? 105 TYR D CE2 1 ATOM 8885 C CZ . TYR D 4 124 ? -51.835 29.945 -14.238 1.00 102.84 ? 105 TYR D CZ 1 ATOM 8886 O OH . TYR D 4 124 ? -52.312 28.921 -13.445 1.00 88.30 ? 105 TYR D OH 1 ATOM 8887 N N . TYR D 4 125 ? -50.353 35.297 -18.998 1.00 94.04 ? 106 TYR D N 1 ATOM 8888 C CA . TYR D 4 125 ? -49.402 36.115 -19.738 1.00 97.06 ? 106 TYR D CA 1 ATOM 8889 C C . TYR D 4 125 ? -50.020 37.349 -20.392 1.00 96.46 ? 106 TYR D C 1 ATOM 8890 O O . TYR D 4 125 ? -49.330 38.113 -21.064 1.00 104.97 ? 106 TYR D O 1 ATOM 8891 C CB . TYR D 4 125 ? -48.695 35.248 -20.780 1.00 100.29 ? 106 TYR D CB 1 ATOM 8892 C CG . TYR D 4 125 ? -48.390 33.851 -20.283 1.00 93.93 ? 106 TYR D CG 1 ATOM 8893 C CD1 . TYR D 4 125 ? -47.606 33.652 -19.155 1.00 89.70 ? 106 TYR D CD1 1 ATOM 8894 C CD2 . TYR D 4 125 ? -48.885 32.732 -20.940 1.00 89.53 ? 106 TYR D CD2 1 ATOM 8895 C CE1 . TYR D 4 125 ? -47.326 32.380 -18.693 1.00 83.67 ? 106 TYR D CE1 1 ATOM 8896 C CE2 . TYR D 4 125 ? -48.606 31.453 -20.485 1.00 86.45 ? 106 TYR D CE2 1 ATOM 8897 C CZ . TYR D 4 125 ? -47.825 31.285 -19.361 1.00 82.23 ? 106 TYR D CZ 1 ATOM 8898 O OH . TYR D 4 125 ? -47.542 30.019 -18.899 1.00 73.19 ? 106 TYR D OH 1 ATOM 8899 N N . GLY D 4 126 ? -51.319 37.542 -20.197 1.00 92.99 ? 107 GLY D N 1 ATOM 8900 C CA . GLY D 4 126 ? -51.996 38.690 -20.771 1.00 103.90 ? 107 GLY D CA 1 ATOM 8901 C C . GLY D 4 126 ? -52.018 38.664 -22.288 1.00 109.31 ? 107 GLY D C 1 ATOM 8902 O O . GLY D 4 126 ? -51.900 37.602 -22.899 1.00 108.98 ? 107 GLY D O 1 ATOM 8903 N N . MET D 4 127 ? -52.158 39.838 -22.898 1.00 113.43 ? 108 MET D N 1 ATOM 8904 C CA . MET D 4 127 ? -52.330 39.938 -24.346 1.00 114.61 ? 108 MET D CA 1 ATOM 8905 C C . MET D 4 127 ? -51.140 40.574 -25.065 1.00 126.00 ? 108 MET D C 1 ATOM 8906 O O . MET D 4 127 ? -50.825 41.746 -24.858 1.00 132.03 ? 108 MET D O 1 ATOM 8907 C CB . MET D 4 127 ? -53.621 40.697 -24.671 1.00 117.79 ? 108 MET D CB 1 ATOM 8908 C CG . MET D 4 127 ? -53.811 41.982 -23.871 1.00 129.04 ? 108 MET D CG 1 ATOM 8909 S SD . MET D 4 127 ? -55.522 42.310 -23.391 1.00 141.91 ? 108 MET D SD 1 ATOM 8910 C CE . MET D 4 127 ? -55.523 41.815 -21.667 1.00 103.98 ? 108 MET D CE 1 ATOM 8911 N N . ASP D 4 128 ? -50.480 39.786 -25.909 1.00 126.13 ? 109 ASP D N 1 ATOM 8912 C CA . ASP D 4 128 ? -49.363 40.276 -26.709 1.00 114.27 ? 109 ASP D CA 1 ATOM 8913 C C . ASP D 4 128 ? -49.836 41.069 -27.924 1.00 116.47 ? 109 ASP D C 1 ATOM 8914 O O . ASP D 4 128 ? -49.336 42.159 -28.202 1.00 119.70 ? 109 ASP D O 1 ATOM 8915 C CB . ASP D 4 128 ? -48.482 39.119 -27.143 1.00 100.46 ? 109 ASP D CB 1 ATOM 8916 N N . VAL D 4 129 ? -50.803 40.508 -28.644 1.00 114.80 ? 110 VAL D N 1 ATOM 8917 C CA . VAL D 4 129 ? -51.330 41.120 -29.859 1.00 118.47 ? 110 VAL D CA 1 ATOM 8918 C C . VAL D 4 129 ? -52.334 42.229 -29.537 1.00 130.44 ? 110 VAL D C 1 ATOM 8919 O O . VAL D 4 129 ? -52.975 42.204 -28.487 1.00 135.73 ? 110 VAL D O 1 ATOM 8920 C CB . VAL D 4 129 ? -52.009 40.063 -30.749 1.00 117.82 ? 110 VAL D CB 1 ATOM 8921 C CG1 . VAL D 4 129 ? -52.063 40.536 -32.194 1.00 130.02 ? 110 VAL D CG1 1 ATOM 8922 C CG2 . VAL D 4 129 ? -51.267 38.736 -30.651 1.00 105.67 ? 110 VAL D CG2 1 ATOM 8923 N N . TRP D 4 130 ? -52.467 43.197 -30.441 1.00 133.19 ? 111 TRP D N 1 ATOM 8924 C CA . TRP D 4 130 ? -53.403 44.304 -30.257 1.00 138.16 ? 111 TRP D CA 1 ATOM 8925 C C . TRP D 4 130 ? -54.023 44.770 -31.573 1.00 145.28 ? 111 TRP D C 1 ATOM 8926 O O . TRP D 4 130 ? -53.502 44.486 -32.651 1.00 142.18 ? 111 TRP D O 1 ATOM 8927 C CB . TRP D 4 130 ? -52.716 45.481 -29.559 1.00 134.44 ? 111 TRP D CB 1 ATOM 8928 C CG . TRP D 4 130 ? -52.524 45.277 -28.090 1.00 141.87 ? 111 TRP D CG 1 ATOM 8929 C CD1 . TRP D 4 130 ? -51.435 44.737 -27.471 1.00 145.31 ? 111 TRP D CD1 1 ATOM 8930 C CD2 . TRP D 4 130 ? -53.453 45.607 -27.051 1.00 146.22 ? 111 TRP D CD2 1 ATOM 8931 N NE1 . TRP D 4 130 ? -51.628 44.711 -26.110 1.00 148.78 ? 111 TRP D NE1 1 ATOM 8932 C CE2 . TRP D 4 130 ? -52.860 45.241 -25.827 1.00 142.33 ? 111 TRP D CE2 1 ATOM 8933 C CE3 . TRP D 4 130 ? -54.729 46.178 -27.037 1.00 146.50 ? 111 TRP D CE3 1 ATOM 8934 C CZ2 . TRP D 4 130 ? -53.499 45.428 -24.603 1.00 130.26 ? 111 TRP D CZ2 1 ATOM 8935 C CZ3 . TRP D 4 130 ? -55.361 46.362 -25.821 1.00 138.80 ? 111 TRP D CZ3 1 ATOM 8936 C CH2 . TRP D 4 130 ? -54.746 45.988 -24.622 1.00 133.22 ? 111 TRP D CH2 1 ATOM 8937 N N . GLY D 4 131 ? -55.140 45.486 -31.473 1.00 156.13 ? 112 GLY D N 1 ATOM 8938 C CA . GLY D 4 131 ? -55.808 46.046 -32.636 1.00 162.01 ? 112 GLY D CA 1 ATOM 8939 C C . GLY D 4 131 ? -55.578 47.542 -32.745 1.00 165.88 ? 112 GLY D C 1 ATOM 8940 O O . GLY D 4 131 ? -54.752 48.098 -32.022 1.00 168.15 ? 112 GLY D O 1 ATOM 8941 N N . ARG D 4 132 ? -56.309 48.198 -33.642 1.00 164.82 ? 113 ARG D N 1 ATOM 8942 C CA . ARG D 4 132 ? -56.160 49.637 -33.831 1.00 166.17 ? 113 ARG D CA 1 ATOM 8943 C C . ARG D 4 132 ? -57.041 50.412 -32.857 1.00 165.60 ? 113 ARG D C 1 ATOM 8944 O O . ARG D 4 132 ? -56.549 50.993 -31.889 1.00 166.99 ? 113 ARG D O 1 ATOM 8945 C CB . ARG D 4 132 ? -56.493 50.019 -35.264 1.00 163.64 ? 113 ARG D CB 1 ATOM 8946 N N . GLY D 4 133 ? -58.345 50.416 -33.115 1.00 162.94 ? 114 GLY D N 1 ATOM 8947 C CA . GLY D 4 133 ? -59.302 50.984 -32.184 1.00 165.97 ? 114 GLY D CA 1 ATOM 8948 C C . GLY D 4 133 ? -60.676 51.223 -32.780 1.00 168.60 ? 114 GLY D C 1 ATOM 8949 O O . GLY D 4 133 ? -60.847 51.248 -33.999 1.00 166.07 ? 114 GLY D O 1 ATOM 8950 N N . THR D 4 134 ? -61.660 51.397 -31.904 1.00 172.84 ? 115 THR D N 1 ATOM 8951 C CA . THR D 4 134 ? -63.014 51.756 -32.305 1.00 172.80 ? 115 THR D CA 1 ATOM 8952 C C . THR D 4 134 ? -63.625 52.684 -31.259 1.00 177.24 ? 115 THR D C 1 ATOM 8953 O O . THR D 4 134 ? -63.574 52.397 -30.063 1.00 176.39 ? 115 THR D O 1 ATOM 8954 C CB . THR D 4 134 ? -63.898 50.505 -32.491 1.00 167.94 ? 115 THR D CB 1 ATOM 8955 O OG1 . THR D 4 134 ? -63.555 49.857 -33.723 1.00 162.58 ? 115 THR D OG1 1 ATOM 8956 C CG2 . THR D 4 134 ? -65.367 50.882 -32.526 1.00 163.47 ? 115 THR D CG2 1 ATOM 8957 N N . THR D 4 135 ? -64.204 53.794 -31.706 1.00 179.88 ? 116 THR D N 1 ATOM 8958 C CA . THR D 4 135 ? -64.802 54.754 -30.785 1.00 180.86 ? 116 THR D CA 1 ATOM 8959 C C . THR D 4 135 ? -66.326 54.732 -30.867 1.00 174.69 ? 116 THR D C 1 ATOM 8960 O O . THR D 4 135 ? -66.911 55.142 -31.869 1.00 166.66 ? 116 THR D O 1 ATOM 8961 C CB . THR D 4 135 ? -64.288 56.188 -31.040 1.00 180.85 ? 116 THR D CB 1 ATOM 8962 O OG1 . THR D 4 135 ? -64.520 56.549 -32.407 1.00 179.55 ? 116 THR D OG1 1 ATOM 8963 C CG2 . THR D 4 135 ? -62.797 56.284 -30.742 1.00 166.83 ? 116 THR D CG2 1 ATOM 8964 N N . VAL D 4 136 ? -66.962 54.248 -29.804 1.00 175.06 ? 117 VAL D N 1 ATOM 8965 C CA . VAL D 4 136 ? -68.417 54.213 -29.727 1.00 177.69 ? 117 VAL D CA 1 ATOM 8966 C C . VAL D 4 136 ? -68.925 55.358 -28.858 1.00 182.26 ? 117 VAL D C 1 ATOM 8967 O O . VAL D 4 136 ? -68.517 55.501 -27.705 1.00 177.00 ? 117 VAL D O 1 ATOM 8968 C CB . VAL D 4 136 ? -68.923 52.874 -29.152 1.00 176.63 ? 117 VAL D CB 1 ATOM 8969 C CG1 . VAL D 4 136 ? -70.433 52.910 -28.962 1.00 174.71 ? 117 VAL D CG1 1 ATOM 8970 C CG2 . VAL D 4 136 ? -68.524 51.721 -30.060 1.00 171.55 ? 117 VAL D CG2 1 ATOM 8971 N N . THR D 4 137 ? -69.813 56.173 -29.418 1.00 183.51 ? 118 THR D N 1 ATOM 8972 C CA . THR D 4 137 ? -70.375 57.306 -28.692 1.00 179.48 ? 118 THR D CA 1 ATOM 8973 C C . THR D 4 137 ? -71.896 57.180 -28.619 1.00 172.53 ? 118 THR D C 1 ATOM 8974 O O . THR D 4 137 ? -72.503 56.435 -29.388 1.00 169.57 ? 118 THR D O 1 ATOM 8975 C CB . THR D 4 137 ? -69.980 58.648 -29.340 1.00 174.23 ? 118 THR D CB 1 ATOM 8976 O OG1 . THR D 4 137 ? -68.710 58.511 -29.988 1.00 175.26 ? 118 THR D OG1 1 ATOM 8977 C CG2 . THR D 4 137 ? -69.890 59.745 -28.289 1.00 168.80 ? 118 THR D CG2 1 ATOM 8978 N N . VAL D 4 138 ? -72.505 57.901 -27.685 1.00 169.69 ? 119 VAL D N 1 ATOM 8979 C CA . VAL D 4 138 ? -73.931 57.757 -27.422 1.00 166.55 ? 119 VAL D CA 1 ATOM 8980 C C . VAL D 4 138 ? -74.692 59.074 -27.569 1.00 165.24 ? 119 VAL D C 1 ATOM 8981 O O . VAL D 4 138 ? -74.399 60.055 -26.887 1.00 168.52 ? 119 VAL D O 1 ATOM 8982 C CB . VAL D 4 138 ? -74.167 57.172 -26.018 1.00 168.86 ? 119 VAL D CB 1 ATOM 8983 C CG1 . VAL D 4 138 ? -75.609 57.342 -25.603 1.00 166.68 ? 119 VAL D CG1 1 ATOM 8984 C CG2 . VAL D 4 138 ? -73.762 55.707 -25.985 1.00 165.43 ? 119 VAL D CG2 1 ATOM 8985 N N . SER D 4 139 ? -75.297 59.695 -28.565 1.00 218.67 ? 120 SER D N 1 ATOM 8986 C CA . SER D 4 139 ? -75.980 60.976 -28.755 1.00 238.52 ? 120 SER D CA 1 ATOM 8987 C C . SER D 4 139 ? -76.836 60.969 -30.018 1.00 254.86 ? 120 SER D C 1 ATOM 8988 O O . SER D 4 139 ? -76.662 60.125 -30.897 1.00 251.03 ? 120 SER D O 1 ATOM 8989 C CB . SER D 4 139 ? -74.971 62.125 -28.854 1.00 242.36 ? 120 SER D CB 1 ATOM 8990 O OG . SER D 4 139 ? -75.619 63.354 -29.137 1.00 249.55 ? 120 SER D OG 1 ATOM 8991 N N . SER D 4 140 ? -77.764 61.917 -30.095 1.00 258.87 ? 121 SER D N 1 ATOM 8992 C CA . SER D 4 140 ? -78.491 62.191 -31.327 1.00 251.17 ? 121 SER D CA 1 ATOM 8993 C C . SER D 4 140 ? -78.128 63.603 -31.771 1.00 254.33 ? 121 SER D C 1 ATOM 8994 O O . SER D 4 140 ? -78.532 64.580 -31.141 1.00 251.66 ? 121 SER D O 1 ATOM 8995 C CB . SER D 4 140 ? -79.999 62.079 -31.098 1.00 212.25 ? 121 SER D CB 1 ATOM 8996 O OG . SER D 4 140 ? -80.338 60.825 -30.531 1.00 176.14 ? 121 SER D OG 1 ATOM 8997 N N . ALA D 4 141 ? -77.370 63.715 -32.857 1.00 248.52 ? 122 ALA D N 1 ATOM 8998 C CA . ALA D 4 141 ? -76.806 65.007 -33.238 1.00 229.91 ? 122 ALA D CA 1 ATOM 8999 C C . ALA D 4 141 ? -76.539 65.151 -34.733 1.00 216.28 ? 122 ALA D C 1 ATOM 9000 O O . ALA D 4 141 ? -76.512 64.167 -35.472 1.00 205.22 ? 122 ALA D O 1 ATOM 9001 C CB . ALA D 4 141 ? -75.532 65.275 -32.447 1.00 220.47 ? 122 ALA D CB 1 ATOM 9002 N N . SER D 4 142 ? -76.350 66.395 -35.164 1.00 222.78 ? 123 SER D N 1 ATOM 9003 C CA . SER D 4 142 ? -76.022 66.699 -36.551 1.00 234.19 ? 123 SER D CA 1 ATOM 9004 C C . SER D 4 142 ? -74.884 67.713 -36.623 1.00 240.73 ? 123 SER D C 1 ATOM 9005 O O . SER D 4 142 ? -74.405 68.192 -35.595 1.00 243.93 ? 123 SER D O 1 ATOM 9006 C CB . SER D 4 142 ? -77.251 67.240 -37.283 1.00 232.13 ? 123 SER D CB 1 ATOM 9007 O OG . SER D 4 142 ? -76.923 67.651 -38.598 1.00 234.76 ? 123 SER D OG 1 ATOM 9008 N N . THR D 4 143 ? -74.459 68.041 -37.839 1.00 241.30 ? 124 THR D N 1 ATOM 9009 C CA . THR D 4 143 ? -73.367 68.988 -38.048 1.00 238.26 ? 124 THR D CA 1 ATOM 9010 C C . THR D 4 143 ? -73.816 70.439 -37.877 1.00 243.69 ? 124 THR D C 1 ATOM 9011 O O . THR D 4 143 ? -75.000 70.750 -38.001 1.00 237.64 ? 124 THR D O 1 ATOM 9012 C CB . THR D 4 143 ? -72.729 68.816 -39.442 1.00 220.23 ? 124 THR D CB 1 ATOM 9013 O OG1 . THR D 4 143 ? -71.614 69.707 -39.575 1.00 223.83 ? 124 THR D OG1 1 ATOM 9014 C CG2 . THR D 4 143 ? -73.744 69.112 -40.535 1.00 204.59 ? 124 THR D CG2 1 ATOM 9015 N N . LYS D 4 144 ? -72.863 71.320 -37.585 1.00 249.90 ? 125 LYS D N 1 ATOM 9016 C CA . LYS D 4 144 ? -73.143 72.748 -37.476 1.00 247.64 ? 125 LYS D CA 1 ATOM 9017 C C . LYS D 4 144 ? -71.887 73.548 -37.820 1.00 251.43 ? 125 LYS D C 1 ATOM 9018 O O . LYS D 4 144 ? -70.823 72.970 -38.045 1.00 255.84 ? 125 LYS D O 1 ATOM 9019 C CB . LYS D 4 144 ? -73.622 73.082 -36.060 1.00 239.15 ? 125 LYS D CB 1 ATOM 9020 C CG . LYS D 4 144 ? -74.497 74.323 -35.960 1.00 222.03 ? 125 LYS D CG 1 ATOM 9021 C CD . LYS D 4 144 ? -74.935 74.572 -34.527 1.00 209.67 ? 125 LYS D CD 1 ATOM 9022 C CE . LYS D 4 144 ? -75.811 75.810 -34.423 1.00 185.55 ? 125 LYS D CE 1 ATOM 9023 N NZ . LYS D 4 144 ? -75.095 77.038 -34.865 1.00 187.27 ? 125 LYS D NZ 1 ATOM 9024 N N . GLY D 4 145 ? -72.005 74.872 -37.857 1.00 247.07 ? 126 GLY D N 1 ATOM 9025 C CA . GLY D 4 145 ? -70.878 75.722 -38.200 1.00 256.40 ? 126 GLY D CA 1 ATOM 9026 C C . GLY D 4 145 ? -70.072 76.215 -37.013 1.00 271.82 ? 126 GLY D C 1 ATOM 9027 O O . GLY D 4 145 ? -70.612 76.397 -35.922 1.00 266.10 ? 126 GLY D O 1 ATOM 9028 N N . PRO D 4 146 ? -68.764 76.437 -37.224 1.00 278.26 ? 127 PRO D N 1 ATOM 9029 C CA . PRO D 4 146 ? -67.824 77.005 -36.253 1.00 278.58 ? 127 PRO D CA 1 ATOM 9030 C C . PRO D 4 146 ? -67.656 78.515 -36.404 1.00 279.62 ? 127 PRO D C 1 ATOM 9031 O O . PRO D 4 146 ? -68.294 79.130 -37.259 1.00 284.33 ? 127 PRO D O 1 ATOM 9032 C CB . PRO D 4 146 ? -66.502 76.302 -36.596 1.00 266.92 ? 127 PRO D CB 1 ATOM 9033 C CG . PRO D 4 146 ? -66.749 75.550 -37.901 1.00 262.41 ? 127 PRO D CG 1 ATOM 9034 C CD . PRO D 4 146 ? -68.064 76.006 -38.441 1.00 269.91 ? 127 PRO D CD 1 ATOM 9035 N N . SER D 4 147 ? -66.793 79.095 -35.574 1.00 276.57 ? 128 SER D N 1 ATOM 9036 C CA . SER D 4 147 ? -66.441 80.509 -35.676 1.00 262.69 ? 128 SER D CA 1 ATOM 9037 C C . SER D 4 147 ? -65.041 80.748 -35.114 1.00 255.43 ? 128 SER D C 1 ATOM 9038 O O . SER D 4 147 ? -64.568 79.991 -34.265 1.00 259.63 ? 128 SER D O 1 ATOM 9039 C CB . SER D 4 147 ? -67.464 81.376 -34.939 1.00 268.81 ? 128 SER D CB 1 ATOM 9040 O OG . SER D 4 147 ? -67.506 81.058 -33.560 1.00 260.75 ? 128 SER D OG 1 ATOM 9041 N N . VAL D 4 148 ? -64.380 81.799 -35.590 1.00 249.15 ? 129 VAL D N 1 ATOM 9042 C CA . VAL D 4 148 ? -63.030 82.124 -35.138 1.00 259.21 ? 129 VAL D CA 1 ATOM 9043 C C . VAL D 4 148 ? -62.946 83.563 -34.636 1.00 262.54 ? 129 VAL D C 1 ATOM 9044 O O . VAL D 4 148 ? -63.456 84.482 -35.277 1.00 257.21 ? 129 VAL D O 1 ATOM 9045 C CB . VAL D 4 148 ? -61.991 81.915 -36.260 1.00 257.61 ? 129 VAL D CB 1 ATOM 9046 C CG1 . VAL D 4 148 ? -60.585 82.205 -35.751 1.00 259.40 ? 129 VAL D CG1 1 ATOM 9047 C CG2 . VAL D 4 148 ? -62.077 80.501 -36.804 1.00 251.26 ? 129 VAL D CG2 1 ATOM 9048 N N . PHE D 4 149 ? -62.301 83.753 -33.488 1.00 268.51 ? 130 PHE D N 1 ATOM 9049 C CA . PHE D 4 149 ? -62.155 85.081 -32.902 1.00 269.98 ? 130 PHE D CA 1 ATOM 9050 C C . PHE D 4 149 ? -60.682 85.411 -32.675 1.00 277.03 ? 130 PHE D C 1 ATOM 9051 O O . PHE D 4 149 ? -59.903 84.545 -32.277 1.00 283.58 ? 130 PHE D O 1 ATOM 9052 C CB . PHE D 4 149 ? -62.924 85.158 -31.582 1.00 272.02 ? 130 PHE D CB 1 ATOM 9053 C CG . PHE D 4 149 ? -64.362 84.736 -31.693 1.00 269.92 ? 130 PHE D CG 1 ATOM 9054 C CD1 . PHE D 4 149 ? -65.166 85.222 -32.713 1.00 269.76 ? 130 PHE D CD1 1 ATOM 9055 C CD2 . PHE D 4 149 ? -64.906 83.841 -30.788 1.00 260.43 ? 130 PHE D CD2 1 ATOM 9056 C CE1 . PHE D 4 149 ? -66.489 84.830 -32.820 1.00 257.49 ? 130 PHE D CE1 1 ATOM 9057 C CE2 . PHE D 4 149 ? -66.226 83.444 -30.890 1.00 257.03 ? 130 PHE D CE2 1 ATOM 9058 C CZ . PHE D 4 149 ? -67.019 83.940 -31.907 1.00 250.49 ? 130 PHE D CZ 1 ATOM 9059 N N . PRO D 4 150 ? -60.298 86.674 -32.927 1.00 276.18 ? 131 PRO D N 1 ATOM 9060 C CA . PRO D 4 150 ? -58.908 87.127 -32.804 1.00 277.62 ? 131 PRO D CA 1 ATOM 9061 C C . PRO D 4 150 ? -58.483 87.323 -31.353 1.00 277.55 ? 131 PRO D C 1 ATOM 9062 O O . PRO D 4 150 ? -59.332 87.521 -30.484 1.00 282.76 ? 131 PRO D O 1 ATOM 9063 C CB . PRO D 4 150 ? -58.911 88.484 -33.525 1.00 275.54 ? 131 PRO D CB 1 ATOM 9064 C CG . PRO D 4 150 ? -60.208 88.545 -34.276 1.00 262.98 ? 131 PRO D CG 1 ATOM 9065 C CD . PRO D 4 150 ? -61.165 87.727 -33.477 1.00 262.09 ? 131 PRO D CD 1 ATOM 9066 N N . LEU D 4 151 ? -57.178 87.273 -31.103 1.00 266.80 ? 132 LEU D N 1 ATOM 9067 C CA . LEU D 4 151 ? -56.641 87.493 -29.765 1.00 264.11 ? 132 LEU D CA 1 ATOM 9068 C C . LEU D 4 151 ? -55.559 88.572 -29.777 1.00 268.23 ? 132 LEU D C 1 ATOM 9069 O O . LEU D 4 151 ? -54.763 88.656 -30.713 1.00 268.84 ? 132 LEU D O 1 ATOM 9070 C CB . LEU D 4 151 ? -56.090 86.189 -29.183 1.00 259.09 ? 132 LEU D CB 1 ATOM 9071 C CG . LEU D 4 151 ? -57.094 85.051 -28.982 1.00 252.36 ? 132 LEU D CG 1 ATOM 9072 C CD1 . LEU D 4 151 ? -56.431 83.860 -28.310 1.00 250.09 ? 132 LEU D CD1 1 ATOM 9073 C CD2 . LEU D 4 151 ? -58.294 85.520 -28.174 1.00 247.36 ? 132 LEU D CD2 1 ATOM 9074 N N . ALA D 4 152 ? -55.538 89.393 -28.732 1.00 275.08 ? 133 ALA D N 1 ATOM 9075 C CA . ALA D 4 152 ? -54.596 90.504 -28.636 1.00 272.69 ? 133 ALA D CA 1 ATOM 9076 C C . ALA D 4 152 ? -54.056 90.621 -27.210 1.00 276.59 ? 133 ALA D C 1 ATOM 9077 O O . ALA D 4 152 ? -54.730 90.220 -26.261 1.00 285.61 ? 133 ALA D O 1 ATOM 9078 C CB . ALA D 4 152 ? -55.274 91.801 -29.063 1.00 254.44 ? 133 ALA D CB 1 ATOM 9079 N N . PRO D 4 153 ? -52.839 91.171 -27.046 1.00 266.76 ? 134 PRO D N 1 ATOM 9080 C CA . PRO D 4 153 ? -51.915 91.678 -28.071 1.00 263.12 ? 134 PRO D CA 1 ATOM 9081 C C . PRO D 4 153 ? -51.236 90.558 -28.853 1.00 259.44 ? 134 PRO D C 1 ATOM 9082 O O . PRO D 4 153 ? -50.704 90.831 -29.929 1.00 248.65 ? 134 PRO D O 1 ATOM 9083 C CB . PRO D 4 153 ? -50.865 92.443 -27.252 1.00 249.73 ? 134 PRO D CB 1 ATOM 9084 C CG . PRO D 4 153 ? -51.480 92.646 -25.902 1.00 243.17 ? 134 PRO D CG 1 ATOM 9085 C CD . PRO D 4 153 ? -52.340 91.449 -25.691 1.00 255.96 ? 134 PRO D CD 1 ATOM 9086 N N . ALA D 4 164 ? -47.149 85.656 -26.893 1.00 236.04 ? 145 ALA D N 1 ATOM 9087 C CA . ALA D 4 164 ? -48.219 84.666 -26.883 1.00 238.93 ? 145 ALA D CA 1 ATOM 9088 C C . ALA D 4 164 ? -49.369 85.092 -27.789 1.00 254.05 ? 145 ALA D C 1 ATOM 9089 O O . ALA D 4 164 ? -50.255 85.836 -27.370 1.00 261.55 ? 145 ALA D O 1 ATOM 9090 C CB . ALA D 4 164 ? -48.717 84.442 -25.463 1.00 221.42 ? 145 ALA D CB 1 ATOM 9091 N N . LEU D 4 165 ? -49.349 84.623 -29.032 1.00 260.12 ? 146 LEU D N 1 ATOM 9092 C CA . LEU D 4 165 ? -50.417 84.936 -29.972 1.00 259.19 ? 146 LEU D CA 1 ATOM 9093 C C . LEU D 4 165 ? -51.203 83.677 -30.316 1.00 262.34 ? 146 LEU D C 1 ATOM 9094 O O . LEU D 4 165 ? -50.714 82.805 -31.033 1.00 269.65 ? 146 LEU D O 1 ATOM 9095 C CB . LEU D 4 165 ? -49.836 85.556 -31.244 1.00 258.24 ? 146 LEU D CB 1 ATOM 9096 C CG . LEU D 4 165 ? -48.874 86.726 -31.026 1.00 245.88 ? 146 LEU D CG 1 ATOM 9097 C CD1 . LEU D 4 165 ? -48.344 87.251 -32.351 1.00 247.68 ? 146 LEU D CD1 1 ATOM 9098 C CD2 . LEU D 4 165 ? -49.556 87.833 -30.243 1.00 231.88 ? 146 LEU D CD2 1 ATOM 9099 N N . GLY D 4 166 ? -52.421 83.586 -29.792 1.00 256.45 ? 147 GLY D N 1 ATOM 9100 C CA . GLY D 4 166 ? -53.282 82.443 -30.036 1.00 259.96 ? 147 GLY D CA 1 ATOM 9101 C C . GLY D 4 166 ? -54.468 82.742 -30.932 1.00 259.07 ? 147 GLY D C 1 ATOM 9102 O O . GLY D 4 166 ? -54.649 83.870 -31.390 1.00 255.41 ? 147 GLY D O 1 ATOM 9103 N N . CYS D 4 167 ? -55.276 81.715 -31.183 1.00 264.23 ? 148 CYS D N 1 ATOM 9104 C CA . CYS D 4 167 ? -56.575 81.884 -31.821 1.00 266.87 ? 148 CYS D CA 1 ATOM 9105 C C . CYS D 4 167 ? -57.639 81.214 -30.959 1.00 266.06 ? 148 CYS D C 1 ATOM 9106 O O . CYS D 4 167 ? -57.322 80.608 -29.936 1.00 266.46 ? 148 CYS D O 1 ATOM 9107 C CB . CYS D 4 167 ? -56.579 81.278 -33.226 1.00 266.81 ? 148 CYS D CB 1 ATOM 9108 S SG . CYS D 4 167 ? -55.709 82.252 -34.477 1.00 321.73 ? 148 CYS D SG 1 ATOM 9109 N N . LEU D 4 168 ? -58.898 81.322 -31.370 1.00 268.70 ? 149 LEU D N 1 ATOM 9110 C CA . LEU D 4 168 ? -59.986 80.683 -30.637 1.00 278.19 ? 149 LEU D CA 1 ATOM 9111 C C . LEU D 4 168 ? -61.081 80.167 -31.564 1.00 282.90 ? 149 LEU D C 1 ATOM 9112 O O . LEU D 4 168 ? -61.508 80.863 -32.486 1.00 275.89 ? 149 LEU D O 1 ATOM 9113 C CB . LEU D 4 168 ? -60.581 81.644 -29.605 1.00 270.63 ? 149 LEU D CB 1 ATOM 9114 C CG . LEU D 4 168 ? -61.744 81.100 -28.770 1.00 258.87 ? 149 LEU D CG 1 ATOM 9115 C CD1 . LEU D 4 168 ? -61.327 79.847 -28.014 1.00 258.26 ? 149 LEU D CD1 1 ATOM 9116 C CD2 . LEU D 4 168 ? -62.268 82.158 -27.811 1.00 242.67 ? 149 LEU D CD2 1 ATOM 9117 N N . VAL D 4 169 ? -61.531 78.942 -31.311 1.00 291.16 ? 150 VAL D N 1 ATOM 9118 C CA . VAL D 4 169 ? -62.631 78.345 -32.061 1.00 283.36 ? 150 VAL D CA 1 ATOM 9119 C C . VAL D 4 169 ? -63.621 77.720 -31.084 1.00 282.86 ? 150 VAL D C 1 ATOM 9120 O O . VAL D 4 169 ? -63.236 76.919 -30.233 1.00 281.23 ? 150 VAL D O 1 ATOM 9121 C CB . VAL D 4 169 ? -62.137 77.251 -33.030 1.00 268.89 ? 150 VAL D CB 1 ATOM 9122 C CG1 . VAL D 4 169 ? -63.281 76.769 -33.910 1.00 258.58 ? 150 VAL D CG1 1 ATOM 9123 C CG2 . VAL D 4 169 ? -60.986 77.762 -33.884 1.00 251.07 ? 150 VAL D CG2 1 ATOM 9124 N N . LYS D 4 170 ? -64.895 78.081 -31.204 1.00 285.82 ? 151 LYS D N 1 ATOM 9125 C CA . LYS D 4 170 ? -65.901 77.580 -30.273 1.00 281.70 ? 151 LYS D CA 1 ATOM 9126 C C . LYS D 4 170 ? -67.189 77.134 -30.961 1.00 282.61 ? 151 LYS D C 1 ATOM 9127 O O . LYS D 4 170 ? -67.527 77.611 -32.046 1.00 281.71 ? 151 LYS D O 1 ATOM 9128 C CB . LYS D 4 170 ? -66.226 78.635 -29.212 1.00 265.27 ? 151 LYS D CB 1 ATOM 9129 C CG . LYS D 4 170 ? -67.098 79.775 -29.717 1.00 254.33 ? 151 LYS D CG 1 ATOM 9130 C CD . LYS D 4 170 ? -67.589 80.648 -28.573 1.00 238.51 ? 151 LYS D CD 1 ATOM 9131 C CE . LYS D 4 170 ? -68.619 81.656 -29.055 1.00 233.67 ? 151 LYS D CE 1 ATOM 9132 N NZ . LYS D 4 170 ? -69.103 82.531 -27.953 1.00 235.23 ? 151 LYS D NZ 1 ATOM 9133 N N . ASP D 4 171 ? -67.893 76.209 -30.313 1.00 279.98 ? 152 ASP D N 1 ATOM 9134 C CA . ASP D 4 171 ? -69.232 75.788 -30.726 1.00 264.47 ? 152 ASP D CA 1 ATOM 9135 C C . ASP D 4 171 ? -69.323 75.253 -32.155 1.00 261.49 ? 152 ASP D C 1 ATOM 9136 O O . ASP D 4 171 ? -69.899 75.900 -33.030 1.00 255.04 ? 152 ASP D O 1 ATOM 9137 C CB . ASP D 4 171 ? -70.236 76.926 -30.521 1.00 259.44 ? 152 ASP D CB 1 ATOM 9138 C CG . ASP D 4 171 ? -70.365 77.333 -29.066 1.00 256.97 ? 152 ASP D CG 1 ATOM 9139 O OD1 . ASP D 4 171 ? -70.222 76.455 -28.188 1.00 244.82 ? 152 ASP D OD1 1 ATOM 9140 O OD2 . ASP D 4 171 ? -70.608 78.529 -28.799 1.00 262.34 ? 152 ASP D OD2 1 ATOM 9141 N N . TYR D 4 172 ? -68.755 74.073 -32.386 1.00 270.89 ? 153 TYR D N 1 ATOM 9142 C CA . TYR D 4 172 ? -68.863 73.421 -33.688 1.00 275.28 ? 153 TYR D CA 1 ATOM 9143 C C . TYR D 4 172 ? -69.246 71.952 -33.532 1.00 265.47 ? 153 TYR D C 1 ATOM 9144 O O . TYR D 4 172 ? -69.358 71.450 -32.412 1.00 259.89 ? 153 TYR D O 1 ATOM 9145 C CB . TYR D 4 172 ? -67.549 73.542 -34.463 1.00 281.97 ? 153 TYR D CB 1 ATOM 9146 C CG . TYR D 4 172 ? -66.444 72.650 -33.944 1.00 284.76 ? 153 TYR D CG 1 ATOM 9147 C CD1 . TYR D 4 172 ? -65.712 73.000 -32.817 1.00 288.31 ? 153 TYR D CD1 1 ATOM 9148 C CD2 . TYR D 4 172 ? -66.130 71.457 -34.584 1.00 273.19 ? 153 TYR D CD2 1 ATOM 9149 C CE1 . TYR D 4 172 ? -64.702 72.186 -32.340 1.00 279.28 ? 153 TYR D CE1 1 ATOM 9150 C CE2 . TYR D 4 172 ? -65.123 70.638 -34.114 1.00 263.33 ? 153 TYR D CE2 1 ATOM 9151 C CZ . TYR D 4 172 ? -64.413 71.007 -32.992 1.00 267.72 ? 153 TYR D CZ 1 ATOM 9152 O OH . TYR D 4 172 ? -63.407 70.195 -32.522 1.00 259.30 ? 153 TYR D OH 1 ATOM 9153 N N . PHE D 4 173 ? -69.420 71.273 -34.664 1.00 264.65 ? 154 PHE D N 1 ATOM 9154 C CA . PHE D 4 173 ? -69.815 69.868 -34.697 1.00 260.88 ? 154 PHE D CA 1 ATOM 9155 C C . PHE D 4 173 ? -69.899 69.419 -36.151 1.00 259.51 ? 154 PHE D C 1 ATOM 9156 O O . PHE D 4 173 ? -70.412 70.152 -36.997 1.00 256.58 ? 154 PHE D O 1 ATOM 9157 C CB . PHE D 4 173 ? -71.189 69.686 -34.043 1.00 251.77 ? 154 PHE D CB 1 ATOM 9158 C CG . PHE D 4 173 ? -71.408 68.325 -33.438 1.00 242.11 ? 154 PHE D CG 1 ATOM 9159 C CD1 . PHE D 4 173 ? -71.804 67.254 -34.223 1.00 231.62 ? 154 PHE D CD1 1 ATOM 9160 C CD2 . PHE D 4 173 ? -71.233 68.122 -32.079 1.00 238.38 ? 154 PHE D CD2 1 ATOM 9161 C CE1 . PHE D 4 173 ? -72.010 66.004 -33.665 1.00 221.36 ? 154 PHE D CE1 1 ATOM 9162 C CE2 . PHE D 4 173 ? -71.440 66.875 -31.515 1.00 226.06 ? 154 PHE D CE2 1 ATOM 9163 C CZ . PHE D 4 173 ? -71.828 65.815 -32.309 1.00 215.24 ? 154 PHE D CZ 1 ATOM 9164 N N . PRO D 4 174 ? -69.395 68.212 -36.454 1.00 260.22 ? 155 PRO D N 1 ATOM 9165 C CA . PRO D 4 174 ? -68.604 67.334 -35.589 1.00 255.51 ? 155 PRO D CA 1 ATOM 9166 C C . PRO D 4 174 ? -67.104 67.583 -35.734 1.00 254.17 ? 155 PRO D C 1 ATOM 9167 O O . PRO D 4 174 ? -66.688 68.524 -36.412 1.00 256.89 ? 155 PRO D O 1 ATOM 9168 C CB . PRO D 4 174 ? -68.948 65.946 -36.119 1.00 247.56 ? 155 PRO D CB 1 ATOM 9169 C CG . PRO D 4 174 ? -69.138 66.168 -37.576 1.00 248.67 ? 155 PRO D CG 1 ATOM 9170 C CD . PRO D 4 174 ? -69.746 67.546 -37.721 1.00 249.77 ? 155 PRO D CD 1 ATOM 9171 N N . GLU D 4 175 ? -66.308 66.736 -35.088 1.00 253.59 ? 156 GLU D N 1 ATOM 9172 C CA . GLU D 4 175 ? -64.856 66.751 -35.223 1.00 260.07 ? 156 GLU D CA 1 ATOM 9173 C C . GLU D 4 175 ? -64.452 66.383 -36.651 1.00 260.09 ? 156 GLU D C 1 ATOM 9174 O O . GLU D 4 175 ? -65.257 65.825 -37.397 1.00 255.76 ? 156 GLU D O 1 ATOM 9175 C CB . GLU D 4 175 ? -64.245 65.737 -34.250 1.00 257.47 ? 156 GLU D CB 1 ATOM 9176 C CG . GLU D 4 175 ? -64.543 66.006 -32.787 1.00 253.13 ? 156 GLU D CG 1 ATOM 9177 C CD . GLU D 4 175 ? -63.727 67.152 -32.230 1.00 258.89 ? 156 GLU D CD 1 ATOM 9178 O OE1 . GLU D 4 175 ? -64.328 68.179 -31.854 1.00 263.27 ? 156 GLU D OE1 1 ATOM 9179 O OE2 . GLU D 4 175 ? -62.485 67.025 -32.164 1.00 255.42 ? 156 GLU D OE2 1 ATOM 9180 N N . PRO D 4 176 ? -63.202 66.689 -37.043 1.00 256.73 ? 157 PRO D N 1 ATOM 9181 C CA . PRO D 4 176 ? -62.199 67.527 -36.379 1.00 248.65 ? 157 PRO D CA 1 ATOM 9182 C C . PRO D 4 176 ? -62.188 68.958 -36.908 1.00 254.21 ? 157 PRO D C 1 ATOM 9183 O O . PRO D 4 176 ? -62.974 69.306 -37.789 1.00 259.42 ? 157 PRO D O 1 ATOM 9184 C CB . PRO D 4 176 ? -60.877 66.833 -36.740 1.00 229.84 ? 157 PRO D CB 1 ATOM 9185 C CG . PRO D 4 176 ? -61.218 65.828 -37.850 1.00 224.34 ? 157 PRO D CG 1 ATOM 9186 C CD . PRO D 4 176 ? -62.640 66.074 -38.252 1.00 238.83 ? 157 PRO D CD 1 ATOM 9187 N N . VAL D 4 177 ? -61.295 69.777 -36.361 1.00 255.35 ? 158 VAL D N 1 ATOM 9188 C CA . VAL D 4 177 ? -60.950 71.061 -36.962 1.00 255.87 ? 158 VAL D CA 1 ATOM 9189 C C . VAL D 4 177 ? -59.433 71.251 -36.919 1.00 256.98 ? 158 VAL D C 1 ATOM 9190 O O . VAL D 4 177 ? -58.831 71.285 -35.845 1.00 254.04 ? 158 VAL D O 1 ATOM 9191 C CB . VAL D 4 177 ? -61.672 72.246 -36.277 1.00 247.38 ? 158 VAL D CB 1 ATOM 9192 C CG1 . VAL D 4 177 ? -61.671 72.084 -34.766 1.00 247.97 ? 158 VAL D CG1 1 ATOM 9193 C CG2 . VAL D 4 177 ? -61.037 73.568 -36.685 1.00 247.59 ? 158 VAL D CG2 1 ATOM 9194 N N . THR D 4 178 ? -58.818 71.364 -38.092 1.00 260.50 ? 159 THR D N 1 ATOM 9195 C CA . THR D 4 178 ? -57.367 71.492 -38.178 1.00 262.25 ? 159 THR D CA 1 ATOM 9196 C C . THR D 4 178 ? -56.935 72.950 -38.131 1.00 279.98 ? 159 THR D C 1 ATOM 9197 O O . THR D 4 178 ? -57.319 73.749 -38.985 1.00 279.12 ? 159 THR D O 1 ATOM 9198 C CB . THR D 4 178 ? -56.810 70.842 -39.458 1.00 242.49 ? 159 THR D CB 1 ATOM 9199 O OG1 . THR D 4 178 ? -57.424 71.439 -40.608 1.00 235.14 ? 159 THR D OG1 1 ATOM 9200 C CG2 . THR D 4 178 ? -57.083 69.346 -39.458 1.00 225.01 ? 159 THR D CG2 1 ATOM 9201 N N . VAL D 4 179 ? -56.134 73.293 -37.128 1.00 294.56 ? 160 VAL D N 1 ATOM 9202 C CA . VAL D 4 179 ? -55.659 74.662 -36.980 1.00 301.42 ? 160 VAL D CA 1 ATOM 9203 C C . VAL D 4 179 ? -54.140 74.773 -37.092 1.00 308.29 ? 160 VAL D C 1 ATOM 9204 O O . VAL D 4 179 ? -53.409 74.304 -36.222 1.00 304.17 ? 160 VAL D O 1 ATOM 9205 C CB . VAL D 4 179 ? -56.122 75.286 -35.648 1.00 288.34 ? 160 VAL D CB 1 ATOM 9206 C CG1 . VAL D 4 179 ? -55.699 76.745 -35.576 1.00 289.76 ? 160 VAL D CG1 1 ATOM 9207 C CG2 . VAL D 4 179 ? -57.629 75.160 -35.499 1.00 268.71 ? 160 VAL D CG2 1 ATOM 9208 N N . SER D 4 180 ? -53.671 75.400 -38.166 1.00 308.85 ? 161 SER D N 1 ATOM 9209 C CA . SER D 4 180 ? -52.241 75.631 -38.351 1.00 294.66 ? 161 SER D CA 1 ATOM 9210 C C . SER D 4 180 ? -51.879 77.097 -38.120 1.00 295.05 ? 161 SER D C 1 ATOM 9211 O O . SER D 4 180 ? -52.740 77.914 -37.797 1.00 300.50 ? 161 SER D O 1 ATOM 9212 C CB . SER D 4 180 ? -51.788 75.174 -39.740 1.00 281.62 ? 161 SER D CB 1 ATOM 9213 O OG . SER D 4 180 ? -52.497 75.848 -40.764 1.00 281.40 ? 161 SER D OG 1 ATOM 9214 N N . TRP D 4 181 ? -50.600 77.422 -38.284 1.00 290.64 ? 162 TRP D N 1 ATOM 9215 C CA . TRP D 4 181 ? -50.125 78.790 -38.106 1.00 285.98 ? 162 TRP D CA 1 ATOM 9216 C C . TRP D 4 181 ? -49.288 79.245 -39.293 1.00 286.36 ? 162 TRP D C 1 ATOM 9217 O O . TRP D 4 181 ? -48.240 78.664 -39.576 1.00 282.47 ? 162 TRP D O 1 ATOM 9218 C CB . TRP D 4 181 ? -49.292 78.911 -36.831 1.00 275.02 ? 162 TRP D CB 1 ATOM 9219 C CG . TRP D 4 181 ? -50.097 78.940 -35.576 1.00 283.78 ? 162 TRP D CG 1 ATOM 9220 C CD1 . TRP D 4 181 ? -50.307 77.907 -34.714 1.00 289.87 ? 162 TRP D CD1 1 ATOM 9221 C CD2 . TRP D 4 181 ? -50.800 80.064 -35.036 1.00 285.23 ? 162 TRP D CD2 1 ATOM 9222 N NE1 . TRP D 4 181 ? -51.098 78.315 -33.668 1.00 286.56 ? 162 TRP D NE1 1 ATOM 9223 C CE2 . TRP D 4 181 ? -51.415 79.636 -33.843 1.00 283.42 ? 162 TRP D CE2 1 ATOM 9224 C CE3 . TRP D 4 181 ? -50.971 81.390 -35.445 1.00 286.26 ? 162 TRP D CE3 1 ATOM 9225 C CZ2 . TRP D 4 181 ? -52.187 80.486 -33.055 1.00 275.51 ? 162 TRP D CZ2 1 ATOM 9226 C CZ3 . TRP D 4 181 ? -51.738 82.232 -34.662 1.00 289.84 ? 162 TRP D CZ3 1 ATOM 9227 C CH2 . TRP D 4 181 ? -52.337 81.777 -33.481 1.00 282.12 ? 162 TRP D CH2 1 ATOM 9228 N N . ASN D 4 182 ? -49.751 80.291 -39.972 1.00 292.02 ? 163 ASN D N 1 ATOM 9229 C CA . ASN D 4 182 ? -49.029 80.866 -41.104 1.00 288.54 ? 163 ASN D CA 1 ATOM 9230 C C . ASN D 4 182 ? -48.665 79.835 -42.166 1.00 275.67 ? 163 ASN D C 1 ATOM 9231 O O . ASN D 4 182 ? -49.553 79.236 -42.775 1.00 266.03 ? 163 ASN D O 1 ATOM 9232 C CB . ASN D 4 182 ? -47.796 81.636 -40.631 1.00 287.93 ? 163 ASN D CB 1 ATOM 9233 C CG . ASN D 4 182 ? -48.149 82.781 -39.704 1.00 289.24 ? 163 ASN D CG 1 ATOM 9234 O OD1 . ASN D 4 182 ? -49.240 83.346 -39.783 1.00 299.46 ? 163 ASN D OD1 1 ATOM 9235 N ND2 . ASN D 4 182 ? -47.227 83.126 -38.815 1.00 267.05 ? 163 ASN D ND2 1 ATOM 9236 N N . SER D 4 183 ? -47.372 79.620 -42.397 1.00 275.26 ? 164 SER D N 1 ATOM 9237 C CA . SER D 4 183 ? -47.005 78.707 -43.466 1.00 272.34 ? 164 SER D CA 1 ATOM 9238 C C . SER D 4 183 ? -46.320 77.421 -43.018 1.00 267.74 ? 164 SER D C 1 ATOM 9239 O O . SER D 4 183 ? -46.982 76.418 -42.748 1.00 254.32 ? 164 SER D O 1 ATOM 9240 C CB . SER D 4 183 ? -46.029 79.438 -44.385 1.00 271.53 ? 164 SER D CB 1 ATOM 9241 O OG . SER D 4 183 ? -46.544 80.701 -44.774 1.00 263.59 ? 164 SER D OG 1 ATOM 9242 N N . GLY D 4 184 ? -44.992 77.452 -42.940 1.00 263.34 ? 165 GLY D N 1 ATOM 9243 C CA . GLY D 4 184 ? -44.230 76.340 -42.401 1.00 253.78 ? 165 GLY D CA 1 ATOM 9244 C C . GLY D 4 184 ? -43.421 76.622 -41.152 1.00 258.99 ? 165 GLY D C 1 ATOM 9245 O O . GLY D 4 184 ? -42.959 75.698 -40.484 1.00 264.38 ? 165 GLY D O 1 ATOM 9246 N N . ALA D 4 185 ? -43.255 77.902 -40.836 1.00 263.10 ? 166 ALA D N 1 ATOM 9247 C CA . ALA D 4 185 ? -42.153 78.320 -39.970 1.00 263.35 ? 166 ALA D CA 1 ATOM 9248 C C . ALA D 4 185 ? -42.401 78.205 -38.479 1.00 272.95 ? 166 ALA D C 1 ATOM 9249 O O . ALA D 4 185 ? -41.451 78.211 -37.697 1.00 264.48 ? 166 ALA D O 1 ATOM 9250 C CB . ALA D 4 185 ? -41.678 79.719 -40.324 1.00 252.34 ? 166 ALA D CB 1 ATOM 9251 N N . LEU D 4 186 ? -43.657 78.109 -38.063 1.00 278.49 ? 167 LEU D N 1 ATOM 9252 C CA . LEU D 4 186 ? -43.866 77.849 -36.658 1.00 277.90 ? 167 LEU D CA 1 ATOM 9253 C C . LEU D 4 186 ? -44.206 76.375 -36.530 1.00 283.20 ? 167 LEU D C 1 ATOM 9254 O O . LEU D 4 186 ? -45.357 75.966 -36.680 1.00 274.04 ? 167 LEU D O 1 ATOM 9255 C CB . LEU D 4 186 ? -45.018 78.714 -36.144 1.00 265.51 ? 167 LEU D CB 1 ATOM 9256 C CG . LEU D 4 186 ? -45.030 80.154 -36.673 1.00 257.88 ? 167 LEU D CG 1 ATOM 9257 C CD1 . LEU D 4 186 ? -46.313 80.873 -36.287 1.00 258.08 ? 167 LEU D CD1 1 ATOM 9258 C CD2 . LEU D 4 186 ? -43.814 80.934 -36.187 1.00 245.53 ? 167 LEU D CD2 1 ATOM 9259 N N . THR D 4 187 ? -43.175 75.583 -36.250 1.00 291.40 ? 168 THR D N 1 ATOM 9260 C CA . THR D 4 187 ? -43.322 74.207 -35.809 1.00 289.52 ? 168 THR D CA 1 ATOM 9261 C C . THR D 4 187 ? -43.025 74.141 -34.321 1.00 291.84 ? 168 THR D C 1 ATOM 9262 O O . THR D 4 187 ? -43.159 73.095 -33.688 1.00 288.81 ? 168 THR D O 1 ATOM 9263 C CB . THR D 4 187 ? -42.390 73.266 -36.588 1.00 273.85 ? 168 THR D CB 1 ATOM 9264 O OG1 . THR D 4 187 ? -41.059 73.795 -36.574 1.00 267.67 ? 168 THR D OG1 1 ATOM 9265 C CG2 . THR D 4 187 ? -42.857 73.135 -38.029 1.00 252.92 ? 168 THR D CG2 1 ATOM 9266 N N . SER D 4 188 ? -42.620 75.283 -33.775 1.00 294.63 ? 169 SER D N 1 ATOM 9267 C CA . SER D 4 188 ? -42.163 75.370 -32.397 1.00 292.82 ? 169 SER D CA 1 ATOM 9268 C C . SER D 4 188 ? -42.824 76.552 -31.707 1.00 299.62 ? 169 SER D C 1 ATOM 9269 O O . SER D 4 188 ? -42.691 77.696 -32.144 1.00 299.39 ? 169 SER D O 1 ATOM 9270 C CB . SER D 4 188 ? -40.641 75.516 -32.347 1.00 281.27 ? 169 SER D CB 1 ATOM 9271 O OG . SER D 4 188 ? -40.220 76.694 -33.016 1.00 282.16 ? 169 SER D OG 1 ATOM 9272 N N . GLY D 4 189 ? -43.534 76.267 -30.623 1.00 297.86 ? 170 GLY D N 1 ATOM 9273 C CA . GLY D 4 189 ? -44.329 77.273 -29.951 1.00 291.87 ? 170 GLY D CA 1 ATOM 9274 C C . GLY D 4 189 ? -45.786 77.075 -30.308 1.00 294.52 ? 170 GLY D C 1 ATOM 9275 O O . GLY D 4 189 ? -46.680 77.556 -29.611 1.00 288.80 ? 170 GLY D O 1 ATOM 9276 N N . VAL D 4 190 ? -46.027 76.353 -31.398 1.00 299.82 ? 171 VAL D N 1 ATOM 9277 C CA . VAL D 4 190 ? -47.389 76.043 -31.809 1.00 294.70 ? 171 VAL D CA 1 ATOM 9278 C C . VAL D 4 190 ? -47.956 74.887 -30.993 1.00 295.69 ? 171 VAL D C 1 ATOM 9279 O O . VAL D 4 190 ? -47.411 73.783 -30.983 1.00 298.56 ? 171 VAL D O 1 ATOM 9280 C CB . VAL D 4 190 ? -47.476 75.706 -33.319 1.00 283.49 ? 171 VAL D CB 1 ATOM 9281 C CG1 . VAL D 4 190 ? -46.321 74.816 -33.742 1.00 283.59 ? 171 VAL D CG1 1 ATOM 9282 C CG2 . VAL D 4 190 ? -48.810 75.050 -33.643 1.00 277.69 ? 171 VAL D CG2 1 ATOM 9283 N N . HIS D 4 191 ? -49.049 75.158 -30.291 1.00 288.45 ? 172 HIS D N 1 ATOM 9284 C CA . HIS D 4 191 ? -49.756 74.123 -29.553 1.00 279.55 ? 172 HIS D CA 1 ATOM 9285 C C . HIS D 4 191 ? -51.231 74.135 -29.918 1.00 281.09 ? 172 HIS D C 1 ATOM 9286 O O . HIS D 4 191 ? -51.951 75.080 -29.602 1.00 285.89 ? 172 HIS D O 1 ATOM 9287 C CB . HIS D 4 191 ? -49.581 74.315 -28.045 1.00 259.32 ? 172 HIS D CB 1 ATOM 9288 C CG . HIS D 4 191 ? -48.237 73.903 -27.535 1.00 254.19 ? 172 HIS D CG 1 ATOM 9289 N ND1 . HIS D 4 191 ? -47.093 74.642 -27.763 1.00 263.46 ? 172 HIS D ND1 1 ATOM 9290 C CD2 . HIS D 4 191 ? -47.849 72.828 -26.811 1.00 228.67 ? 172 HIS D CD2 1 ATOM 9291 C CE1 . HIS D 4 191 ? -46.064 74.040 -27.199 1.00 245.59 ? 172 HIS D CE1 1 ATOM 9292 N NE2 . HIS D 4 191 ? -46.494 72.935 -26.614 1.00 226.71 ? 172 HIS D NE2 1 ATOM 9293 N N . THR D 4 192 ? -51.675 73.074 -30.582 1.00 283.81 ? 173 THR D N 1 ATOM 9294 C CA . THR D 4 192 ? -53.073 72.942 -30.962 1.00 281.22 ? 173 THR D CA 1 ATOM 9295 C C . THR D 4 192 ? -53.806 72.105 -29.923 1.00 281.28 ? 173 THR D C 1 ATOM 9296 O O . THR D 4 192 ? -53.522 70.919 -29.751 1.00 277.60 ? 173 THR D O 1 ATOM 9297 C CB . THR D 4 192 ? -53.221 72.300 -32.351 1.00 271.81 ? 173 THR D CB 1 ATOM 9298 O OG1 . THR D 4 192 ? -52.644 70.988 -32.338 1.00 272.79 ? 173 THR D OG1 1 ATOM 9299 C CG2 . THR D 4 192 ? -52.514 73.144 -33.397 1.00 256.51 ? 173 THR D CG2 1 ATOM 9300 N N . PHE D 4 193 ? -54.748 72.733 -29.229 1.00 280.65 ? 174 PHE D N 1 ATOM 9301 C CA . PHE D 4 193 ? -55.439 72.091 -28.117 1.00 272.83 ? 174 PHE D CA 1 ATOM 9302 C C . PHE D 4 193 ? -56.542 71.148 -28.585 1.00 265.58 ? 174 PHE D C 1 ATOM 9303 O O . PHE D 4 193 ? -57.259 71.448 -29.539 1.00 263.13 ? 174 PHE D O 1 ATOM 9304 C CB . PHE D 4 193 ? -56.014 73.148 -27.170 1.00 268.76 ? 174 PHE D CB 1 ATOM 9305 C CG . PHE D 4 193 ? -54.979 74.070 -26.590 1.00 269.52 ? 174 PHE D CG 1 ATOM 9306 C CD1 . PHE D 4 193 ? -54.367 73.772 -25.386 1.00 259.24 ? 174 PHE D CD1 1 ATOM 9307 C CD2 . PHE D 4 193 ? -54.619 75.234 -27.250 1.00 270.92 ? 174 PHE D CD2 1 ATOM 9308 C CE1 . PHE D 4 193 ? -53.413 74.615 -24.851 1.00 250.47 ? 174 PHE D CE1 1 ATOM 9309 C CE2 . PHE D 4 193 ? -53.667 76.081 -26.719 1.00 264.05 ? 174 PHE D CE2 1 ATOM 9310 C CZ . PHE D 4 193 ? -53.063 75.771 -25.518 1.00 252.23 ? 174 PHE D CZ 1 ATOM 9311 N N . PRO D 4 194 ? -56.671 69.994 -27.911 1.00 258.50 ? 175 PRO D N 1 ATOM 9312 C CA . PRO D 4 194 ? -57.751 69.037 -28.174 1.00 249.46 ? 175 PRO D CA 1 ATOM 9313 C C . PRO D 4 194 ? -59.115 69.645 -27.861 1.00 260.24 ? 175 PRO D C 1 ATOM 9314 O O . PRO D 4 194 ? -59.199 70.605 -27.096 1.00 259.53 ? 175 PRO D O 1 ATOM 9315 C CB . PRO D 4 194 ? -57.449 67.895 -27.198 1.00 231.38 ? 175 PRO D CB 1 ATOM 9316 C CG . PRO D 4 194 ? -55.987 68.009 -26.918 1.00 234.03 ? 175 PRO D CG 1 ATOM 9317 C CD . PRO D 4 194 ? -55.709 69.480 -26.922 1.00 253.43 ? 175 PRO D CD 1 ATOM 9318 N N . ALA D 4 195 ? -60.169 69.086 -28.446 1.00 265.40 ? 176 ALA D N 1 ATOM 9319 C CA . ALA D 4 195 ? -61.516 69.616 -28.261 1.00 264.71 ? 176 ALA D CA 1 ATOM 9320 C C . ALA D 4 195 ? -62.101 69.241 -26.903 1.00 253.13 ? 176 ALA D C 1 ATOM 9321 O O . ALA D 4 195 ? -61.769 68.200 -26.336 1.00 245.63 ? 176 ALA D O 1 ATOM 9322 C CB . ALA D 4 195 ? -62.429 69.136 -29.378 1.00 259.26 ? 176 ALA D CB 1 ATOM 9323 N N . VAL D 4 196 ? -62.971 70.103 -26.384 1.00 254.50 ? 177 VAL D N 1 ATOM 9324 C CA . VAL D 4 196 ? -63.705 69.816 -25.157 1.00 243.96 ? 177 VAL D CA 1 ATOM 9325 C C . VAL D 4 196 ? -65.195 70.055 -25.371 1.00 249.90 ? 177 VAL D C 1 ATOM 9326 O O . VAL D 4 196 ? -65.599 71.110 -25.862 1.00 253.91 ? 177 VAL D O 1 ATOM 9327 C CB . VAL D 4 196 ? -63.216 70.675 -23.974 1.00 231.30 ? 177 VAL D CB 1 ATOM 9328 C CG1 . VAL D 4 196 ? -64.030 70.366 -22.725 1.00 222.55 ? 177 VAL D CG1 1 ATOM 9329 C CG2 . VAL D 4 196 ? -61.742 70.433 -23.715 1.00 230.89 ? 177 VAL D CG2 1 ATOM 9330 N N . LEU D 4 197 ? -66.009 69.073 -24.998 1.00 246.58 ? 178 LEU D N 1 ATOM 9331 C CA . LEU D 4 197 ? -67.450 69.145 -25.214 1.00 244.85 ? 178 LEU D CA 1 ATOM 9332 C C . LEU D 4 197 ? -68.135 70.092 -24.232 1.00 235.88 ? 178 LEU D C 1 ATOM 9333 O O . LEU D 4 197 ? -68.012 69.938 -23.017 1.00 227.24 ? 178 LEU D O 1 ATOM 9334 C CB . LEU D 4 197 ? -68.070 67.749 -25.110 1.00 232.71 ? 178 LEU D CB 1 ATOM 9335 C CG . LEU D 4 197 ? -69.584 67.659 -25.310 1.00 223.21 ? 178 LEU D CG 1 ATOM 9336 C CD1 . LEU D 4 197 ? -69.968 68.142 -26.699 1.00 233.52 ? 178 LEU D CD1 1 ATOM 9337 C CD2 . LEU D 4 197 ? -70.076 66.238 -25.075 1.00 198.17 ? 178 LEU D CD2 1 ATOM 9338 N N . GLN D 4 198 ? -68.858 71.071 -24.769 1.00 237.50 ? 179 GLN D N 1 ATOM 9339 C CA . GLN D 4 198 ? -69.646 71.984 -23.950 1.00 228.56 ? 179 GLN D CA 1 ATOM 9340 C C . GLN D 4 198 ? -70.927 71.302 -23.487 1.00 234.39 ? 179 GLN D C 1 ATOM 9341 O O . GLN D 4 198 ? -71.182 70.146 -23.824 1.00 229.10 ? 179 GLN D O 1 ATOM 9342 C CB . GLN D 4 198 ? -69.995 73.251 -24.735 1.00 229.65 ? 179 GLN D CB 1 ATOM 9343 C CG . GLN D 4 198 ? -68.861 74.256 -24.858 1.00 225.59 ? 179 GLN D CG 1 ATOM 9344 C CD . GLN D 4 198 ? -68.756 75.167 -23.650 1.00 229.14 ? 179 GLN D CD 1 ATOM 9345 O OE1 . GLN D 4 198 ? -69.514 75.033 -22.689 1.00 220.53 ? 179 GLN D OE1 1 ATOM 9346 N NE2 . GLN D 4 198 ? -67.817 76.105 -23.696 1.00 242.31 ? 179 GLN D NE2 1 ATOM 9347 N N . SER D 4 199 ? -71.734 72.024 -22.719 1.00 242.01 ? 180 SER D N 1 ATOM 9348 C CA . SER D 4 199 ? -73.022 71.507 -22.276 1.00 239.76 ? 180 SER D CA 1 ATOM 9349 C C . SER D 4 199 ? -74.080 71.729 -23.352 1.00 240.36 ? 180 SER D C 1 ATOM 9350 O O . SER D 4 199 ? -75.213 71.263 -23.230 1.00 224.89 ? 180 SER D O 1 ATOM 9351 C CB . SER D 4 199 ? -73.446 72.171 -20.965 1.00 218.37 ? 180 SER D CB 1 ATOM 9352 O OG . SER D 4 199 ? -72.513 71.904 -19.933 1.00 190.16 ? 180 SER D OG 1 ATOM 9353 N N . SER D 4 200 ? -73.698 72.444 -24.406 1.00 255.04 ? 181 SER D N 1 ATOM 9354 C CA . SER D 4 200 ? -74.599 72.724 -25.517 1.00 252.95 ? 181 SER D CA 1 ATOM 9355 C C . SER D 4 200 ? -74.500 71.647 -26.594 1.00 253.10 ? 181 SER D C 1 ATOM 9356 O O . SER D 4 200 ? -75.150 71.736 -27.635 1.00 256.24 ? 181 SER D O 1 ATOM 9357 C CB . SER D 4 200 ? -74.297 74.097 -26.122 1.00 251.07 ? 181 SER D CB 1 ATOM 9358 O OG . SER D 4 200 ? -72.994 74.135 -26.680 1.00 250.88 ? 181 SER D OG 1 ATOM 9359 N N . GLY D 4 201 ? -73.678 70.635 -26.338 1.00 246.29 ? 182 GLY D N 1 ATOM 9360 C CA . GLY D 4 201 ? -73.506 69.536 -27.271 1.00 239.95 ? 182 GLY D CA 1 ATOM 9361 C C . GLY D 4 201 ? -72.510 69.840 -28.373 1.00 246.95 ? 182 GLY D C 1 ATOM 9362 O O . GLY D 4 201 ? -72.314 69.037 -29.284 1.00 235.56 ? 182 GLY D O 1 ATOM 9363 N N . LEU D 4 202 ? -71.875 71.005 -28.287 1.00 258.03 ? 183 LEU D N 1 ATOM 9364 C CA . LEU D 4 202 ? -70.883 71.418 -29.272 1.00 255.12 ? 183 LEU D CA 1 ATOM 9365 C C . LEU D 4 202 ? -69.501 71.443 -28.629 1.00 252.78 ? 183 LEU D C 1 ATOM 9366 O O . LEU D 4 202 ? -69.379 71.669 -27.426 1.00 250.97 ? 183 LEU D O 1 ATOM 9367 C CB . LEU D 4 202 ? -71.232 72.800 -29.826 1.00 254.06 ? 183 LEU D CB 1 ATOM 9368 C CG . LEU D 4 202 ? -72.630 72.958 -30.429 1.00 244.96 ? 183 LEU D CG 1 ATOM 9369 C CD1 . LEU D 4 202 ? -72.880 74.399 -30.846 1.00 235.48 ? 183 LEU D CD1 1 ATOM 9370 C CD2 . LEU D 4 202 ? -72.818 72.018 -31.609 1.00 241.29 ? 183 LEU D CD2 1 ATOM 9371 N N . TYR D 4 203 ? -68.461 71.207 -29.422 1.00 259.94 ? 184 TYR D N 1 ATOM 9372 C CA . TYR D 4 203 ? -67.109 71.188 -28.879 1.00 266.76 ? 184 TYR D CA 1 ATOM 9373 C C . TYR D 4 203 ? -66.443 72.555 -28.991 1.00 272.69 ? 184 TYR D C 1 ATOM 9374 O O . TYR D 4 203 ? -66.992 73.481 -29.589 1.00 281.56 ? 184 TYR D O 1 ATOM 9375 C CB . TYR D 4 203 ? -66.256 70.146 -29.607 1.00 271.32 ? 184 TYR D CB 1 ATOM 9376 C CG . TYR D 4 203 ? -66.788 68.733 -29.525 1.00 264.45 ? 184 TYR D CG 1 ATOM 9377 C CD1 . TYR D 4 203 ? -67.706 68.260 -30.453 1.00 251.12 ? 184 TYR D CD1 1 ATOM 9378 C CD2 . TYR D 4 203 ? -66.363 67.868 -28.524 1.00 260.94 ? 184 TYR D CD2 1 ATOM 9379 C CE1 . TYR D 4 203 ? -68.192 66.968 -30.383 1.00 237.69 ? 184 TYR D CE1 1 ATOM 9380 C CE2 . TYR D 4 203 ? -66.843 66.575 -28.446 1.00 249.96 ? 184 TYR D CE2 1 ATOM 9381 C CZ . TYR D 4 203 ? -67.757 66.131 -29.378 1.00 235.95 ? 184 TYR D CZ 1 ATOM 9382 O OH . TYR D 4 203 ? -68.238 64.844 -29.305 1.00 222.06 ? 184 TYR D OH 1 ATOM 9383 N N . SER D 4 204 ? -65.254 72.667 -28.408 1.00 268.65 ? 185 SER D N 1 ATOM 9384 C CA . SER D 4 204 ? -64.435 73.867 -28.532 1.00 269.08 ? 185 SER D CA 1 ATOM 9385 C C . SER D 4 204 ? -62.960 73.543 -28.307 1.00 273.16 ? 185 SER D C 1 ATOM 9386 O O . SER D 4 204 ? -62.627 72.646 -27.532 1.00 272.92 ? 185 SER D O 1 ATOM 9387 C CB . SER D 4 204 ? -64.908 74.950 -27.558 1.00 260.73 ? 185 SER D CB 1 ATOM 9388 O OG . SER D 4 204 ? -65.104 74.420 -26.260 1.00 253.62 ? 185 SER D OG 1 ATOM 9389 N N . LEU D 4 205 ? -62.082 74.279 -28.979 1.00 280.62 ? 186 LEU D N 1 ATOM 9390 C CA . LEU D 4 205 ? -60.643 74.121 -28.789 1.00 281.24 ? 186 LEU D CA 1 ATOM 9391 C C . LEU D 4 205 ? -59.896 75.395 -29.173 1.00 279.79 ? 186 LEU D C 1 ATOM 9392 O O . LEU D 4 205 ? -60.514 76.425 -29.438 1.00 285.70 ? 186 LEU D O 1 ATOM 9393 C CB . LEU D 4 205 ? -60.113 72.912 -29.570 1.00 274.37 ? 186 LEU D CB 1 ATOM 9394 C CG . LEU D 4 205 ? -60.406 72.769 -31.068 1.00 259.30 ? 186 LEU D CG 1 ATOM 9395 C CD1 . LEU D 4 205 ? -59.428 73.569 -31.919 1.00 247.69 ? 186 LEU D CD1 1 ATOM 9396 C CD2 . LEU D 4 205 ? -60.380 71.303 -31.466 1.00 247.72 ? 186 LEU D CD2 1 ATOM 9397 N N . SER D 4 206 ? -58.569 75.322 -29.202 1.00 273.07 ? 187 SER D N 1 ATOM 9398 C CA . SER D 4 206 ? -57.760 76.479 -29.563 1.00 272.06 ? 187 SER D CA 1 ATOM 9399 C C . SER D 4 206 ? -56.377 76.094 -30.078 1.00 273.55 ? 187 SER D C 1 ATOM 9400 O O . SER D 4 206 ? -56.016 74.918 -30.113 1.00 276.53 ? 187 SER D O 1 ATOM 9401 C CB . SER D 4 206 ? -57.617 77.418 -28.362 1.00 272.30 ? 187 SER D CB 1 ATOM 9402 O OG . SER D 4 206 ? -56.684 78.452 -28.630 1.00 272.23 ? 187 SER D OG 1 ATOM 9403 N N . SER D 4 207 ? -55.614 77.104 -30.483 1.00 274.04 ? 188 SER D N 1 ATOM 9404 C CA . SER D 4 207 ? -54.224 76.927 -30.882 1.00 273.70 ? 188 SER D CA 1 ATOM 9405 C C . SER D 4 207 ? -53.447 78.199 -30.564 1.00 277.27 ? 188 SER D C 1 ATOM 9406 O O . SER D 4 207 ? -53.969 79.303 -30.723 1.00 269.78 ? 188 SER D O 1 ATOM 9407 C CB . SER D 4 207 ? -54.123 76.598 -32.370 1.00 259.01 ? 188 SER D CB 1 ATOM 9408 O OG . SER D 4 207 ? -54.810 75.397 -32.674 1.00 255.52 ? 188 SER D OG 1 ATOM 9409 N N . VAL D 4 208 ? -52.203 78.047 -30.119 1.00 287.64 ? 189 VAL D N 1 ATOM 9410 C CA . VAL D 4 208 ? -51.411 79.192 -29.675 1.00 282.75 ? 189 VAL D CA 1 ATOM 9411 C C . VAL D 4 208 ? -49.965 79.140 -30.166 1.00 280.70 ? 189 VAL D C 1 ATOM 9412 O O . VAL D 4 208 ? -49.458 78.080 -30.528 1.00 283.52 ? 189 VAL D O 1 ATOM 9413 C CB . VAL D 4 208 ? -51.394 79.301 -28.134 1.00 276.16 ? 189 VAL D CB 1 ATOM 9414 C CG1 . VAL D 4 208 ? -52.793 79.569 -27.596 1.00 264.26 ? 189 VAL D CG1 1 ATOM 9415 C CG2 . VAL D 4 208 ? -50.810 78.039 -27.519 1.00 261.77 ? 189 VAL D CG2 1 ATOM 9416 N N . VAL D 4 209 ? -49.312 80.299 -30.173 1.00 278.54 ? 190 VAL D N 1 ATOM 9417 C CA . VAL D 4 209 ? -47.891 80.397 -30.492 1.00 273.45 ? 190 VAL D CA 1 ATOM 9418 C C . VAL D 4 209 ? -47.299 81.581 -29.724 1.00 271.16 ? 190 VAL D C 1 ATOM 9419 O O . VAL D 4 209 ? -48.022 82.508 -29.358 1.00 272.15 ? 190 VAL D O 1 ATOM 9420 C CB . VAL D 4 209 ? -47.649 80.541 -32.011 1.00 266.84 ? 190 VAL D CB 1 ATOM 9421 C CG1 . VAL D 4 209 ? -47.932 81.961 -32.472 1.00 260.84 ? 190 VAL D CG1 1 ATOM 9422 C CG2 . VAL D 4 209 ? -46.226 80.131 -32.370 1.00 252.99 ? 190 VAL D CG2 1 ATOM 9423 N N . THR D 4 210 ? -45.996 81.544 -29.455 1.00 269.75 ? 191 THR D N 1 ATOM 9424 C CA . THR D 4 210 ? -45.382 82.550 -28.589 1.00 263.42 ? 191 THR D CA 1 ATOM 9425 C C . THR D 4 210 ? -44.197 83.289 -29.208 1.00 261.77 ? 191 THR D C 1 ATOM 9426 O O . THR D 4 210 ? -43.147 82.700 -29.460 1.00 246.48 ? 191 THR D O 1 ATOM 9427 C CB . THR D 4 210 ? -44.921 81.925 -27.259 1.00 248.52 ? 191 THR D CB 1 ATOM 9428 O OG1 . THR D 4 210 ? -44.013 80.850 -27.524 1.00 238.56 ? 191 THR D OG1 1 ATOM 9429 C CG2 . THR D 4 210 ? -46.114 81.394 -26.483 1.00 233.28 ? 191 THR D CG2 1 ATOM 9430 N N . VAL D 4 211 ? -44.380 84.585 -29.452 1.00 269.46 ? 192 VAL D N 1 ATOM 9431 C CA . VAL D 4 211 ? -43.285 85.457 -29.879 1.00 256.95 ? 192 VAL D CA 1 ATOM 9432 C C . VAL D 4 211 ? -42.246 85.762 -28.782 1.00 248.32 ? 192 VAL D C 1 ATOM 9433 O O . VAL D 4 211 ? -41.051 85.557 -28.998 1.00 243.93 ? 192 VAL D O 1 ATOM 9434 C CB . VAL D 4 211 ? -43.795 86.774 -30.521 1.00 248.56 ? 192 VAL D CB 1 ATOM 9435 C CG1 . VAL D 4 211 ? -42.626 87.654 -30.934 1.00 222.27 ? 192 VAL D CG1 1 ATOM 9436 C CG2 . VAL D 4 211 ? -44.687 86.474 -31.710 1.00 238.45 ? 192 VAL D CG2 1 ATOM 9437 N N . PRO D 4 212 ? -42.690 86.249 -27.602 1.00 246.60 ? 193 PRO D N 1 ATOM 9438 C CA . PRO D 4 212 ? -41.681 86.613 -26.602 1.00 240.62 ? 193 PRO D CA 1 ATOM 9439 C C . PRO D 4 212 ? -41.069 85.390 -25.928 1.00 238.66 ? 193 PRO D C 1 ATOM 9440 O O . PRO D 4 212 ? -40.458 85.544 -24.870 1.00 211.21 ? 193 PRO D O 1 ATOM 9441 C CB . PRO D 4 212 ? -42.479 87.430 -25.573 1.00 220.71 ? 193 PRO D CB 1 ATOM 9442 C CG . PRO D 4 212 ? -43.792 87.742 -26.230 1.00 212.57 ? 193 PRO D CG 1 ATOM 9443 C CD . PRO D 4 212 ? -44.045 86.587 -27.134 1.00 230.04 ? 193 PRO D CD 1 ATOM 9444 N N . THR D 4 220 ? -46.862 90.261 -36.612 1.00 213.19 ? 201 THR D N 1 ATOM 9445 C CA . THR D 4 220 ? -48.271 90.052 -36.924 1.00 239.76 ? 201 THR D CA 1 ATOM 9446 C C . THR D 4 220 ? -48.471 88.772 -37.728 1.00 263.00 ? 201 THR D C 1 ATOM 9447 O O . THR D 4 220 ? -47.903 88.612 -38.809 1.00 260.78 ? 201 THR D O 1 ATOM 9448 C CB . THR D 4 220 ? -48.856 91.241 -37.710 1.00 229.64 ? 201 THR D CB 1 ATOM 9449 O OG1 . THR D 4 220 ? -48.118 91.423 -38.925 1.00 221.06 ? 201 THR D OG1 1 ATOM 9450 C CG2 . THR D 4 220 ? -48.778 92.515 -36.883 1.00 214.16 ? 201 THR D CG2 1 ATOM 9451 N N . TYR D 4 221 ? -49.280 87.860 -37.196 1.00 276.12 ? 202 TYR D N 1 ATOM 9452 C CA . TYR D 4 221 ? -49.551 86.598 -37.873 1.00 285.68 ? 202 TYR D CA 1 ATOM 9453 C C . TYR D 4 221 ? -51.049 86.365 -38.034 1.00 292.33 ? 202 TYR D C 1 ATOM 9454 O O . TYR D 4 221 ? -51.864 87.212 -37.671 1.00 290.53 ? 202 TYR D O 1 ATOM 9455 C CB . TYR D 4 221 ? -48.926 85.428 -37.109 1.00 280.24 ? 202 TYR D CB 1 ATOM 9456 C CG . TYR D 4 221 ? -47.506 85.672 -36.655 1.00 263.58 ? 202 TYR D CG 1 ATOM 9457 C CD1 . TYR D 4 221 ? -46.492 85.916 -37.573 1.00 250.87 ? 202 TYR D CD1 1 ATOM 9458 C CD2 . TYR D 4 221 ? -47.177 85.648 -35.308 1.00 246.59 ? 202 TYR D CD2 1 ATOM 9459 C CE1 . TYR D 4 221 ? -45.192 86.136 -37.159 1.00 239.48 ? 202 TYR D CE1 1 ATOM 9460 C CE2 . TYR D 4 221 ? -45.882 85.865 -34.886 1.00 225.55 ? 202 TYR D CE2 1 ATOM 9461 C CZ . TYR D 4 221 ? -44.894 86.109 -35.813 1.00 228.13 ? 202 TYR D CZ 1 ATOM 9462 O OH . TYR D 4 221 ? -43.602 86.326 -35.391 1.00 210.70 ? 202 TYR D OH 1 ATOM 9463 N N . ILE D 4 222 ? -51.400 85.207 -38.583 1.00 302.52 ? 203 ILE D N 1 ATOM 9464 C CA . ILE D 4 222 ? -52.797 84.835 -38.775 1.00 310.04 ? 203 ILE D CA 1 ATOM 9465 C C . ILE D 4 222 ? -53.044 83.390 -38.353 1.00 319.54 ? 203 ILE D C 1 ATOM 9466 O O . ILE D 4 222 ? -52.243 82.501 -38.646 1.00 317.20 ? 203 ILE D O 1 ATOM 9467 C CB . ILE D 4 222 ? -53.258 85.029 -40.244 1.00 295.12 ? 203 ILE D CB 1 ATOM 9468 C CG1 . ILE D 4 222 ? -52.305 84.329 -41.221 1.00 275.67 ? 203 ILE D CG1 1 ATOM 9469 C CG2 . ILE D 4 222 ? -53.389 86.509 -40.576 1.00 285.42 ? 203 ILE D CG2 1 ATOM 9470 C CD1 . ILE D 4 222 ? -51.192 85.213 -41.767 1.00 245.81 ? 203 ILE D CD1 1 ATOM 9471 N N . CYS D 4 223 ? -54.151 83.161 -37.653 1.00 329.86 ? 204 CYS D N 1 ATOM 9472 C CA . CYS D 4 223 ? -54.517 81.810 -37.244 1.00 319.46 ? 204 CYS D CA 1 ATOM 9473 C C . CYS D 4 223 ? -55.267 81.101 -38.365 1.00 307.37 ? 204 CYS D C 1 ATOM 9474 O O . CYS D 4 223 ? -56.202 81.650 -38.949 1.00 298.76 ? 204 CYS D O 1 ATOM 9475 C CB . CYS D 4 223 ? -55.349 81.829 -35.959 1.00 318.42 ? 204 CYS D CB 1 ATOM 9476 S SG . CYS D 4 223 ? -56.885 82.776 -36.050 1.00 311.75 ? 204 CYS D SG 1 ATOM 9477 N N . ASN D 4 224 ? -54.845 79.878 -38.662 1.00 302.67 ? 205 ASN D N 1 ATOM 9478 C CA . ASN D 4 224 ? -55.403 79.124 -39.773 1.00 293.64 ? 205 ASN D CA 1 ATOM 9479 C C . ASN D 4 224 ? -56.398 78.075 -39.298 1.00 286.07 ? 205 ASN D C 1 ATOM 9480 O O . ASN D 4 224 ? -56.002 77.067 -38.733 1.00 295.42 ? 205 ASN D O 1 ATOM 9481 C CB . ASN D 4 224 ? -54.271 78.438 -40.539 1.00 292.19 ? 205 ASN D CB 1 ATOM 9482 C CG . ASN D 4 224 ? -53.291 79.427 -41.144 1.00 281.37 ? 205 ASN D CG 1 ATOM 9483 O OD1 . ASN D 4 224 ? -53.609 80.603 -41.323 1.00 276.94 ? 205 ASN D OD1 1 ATOM 9484 N ND2 . ASN D 4 224 ? -52.096 78.950 -41.475 1.00 274.21 ? 205 ASN D ND2 1 ATOM 9485 N N . VAL D 4 225 ? -57.685 78.294 -39.553 1.00 270.64 ? 206 VAL D N 1 ATOM 9486 C CA . VAL D 4 225 ? -58.720 77.396 -39.040 1.00 270.83 ? 206 VAL D CA 1 ATOM 9487 C C . VAL D 4 225 ? -59.622 76.843 -40.141 1.00 273.95 ? 206 VAL D C 1 ATOM 9488 O O . VAL D 4 225 ? -60.250 77.603 -40.874 1.00 274.40 ? 206 VAL D O 1 ATOM 9489 C CB . VAL D 4 225 ? -59.602 78.101 -37.994 1.00 257.67 ? 206 VAL D CB 1 ATOM 9490 C CG1 . VAL D 4 225 ? -60.691 77.161 -37.501 1.00 249.76 ? 206 VAL D CG1 1 ATOM 9491 C CG2 . VAL D 4 225 ? -58.755 78.603 -36.835 1.00 260.08 ? 206 VAL D CG2 1 ATOM 9492 N N . ASN D 4 226 ? -59.699 75.519 -40.239 1.00 273.13 ? 207 ASN D N 1 ATOM 9493 C CA . ASN D 4 226 ? -60.501 74.875 -41.275 1.00 270.32 ? 207 ASN D CA 1 ATOM 9494 C C . ASN D 4 226 ? -61.428 73.793 -40.724 1.00 266.13 ? 207 ASN D C 1 ATOM 9495 O O . ASN D 4 226 ? -61.029 72.997 -39.874 1.00 256.85 ? 207 ASN D O 1 ATOM 9496 C CB . ASN D 4 226 ? -59.593 74.282 -42.354 1.00 258.96 ? 207 ASN D CB 1 ATOM 9497 C CG . ASN D 4 226 ? -60.362 73.827 -43.579 1.00 239.67 ? 207 ASN D CG 1 ATOM 9498 O OD1 . ASN D 4 226 ? -61.414 74.376 -43.905 1.00 243.43 ? 207 ASN D OD1 1 ATOM 9499 N ND2 . ASN D 4 226 ? -59.838 72.818 -44.265 1.00 200.60 ? 207 ASN D ND2 1 ATOM 9500 N N . HIS D 4 227 ? -62.663 73.767 -41.217 1.00 273.23 ? 208 HIS D N 1 ATOM 9501 C CA . HIS D 4 227 ? -63.651 72.788 -40.771 1.00 271.55 ? 208 HIS D CA 1 ATOM 9502 C C . HIS D 4 227 ? -64.228 72.022 -41.958 1.00 278.31 ? 208 HIS D C 1 ATOM 9503 O O . HIS D 4 227 ? -64.897 72.599 -42.814 1.00 279.78 ? 208 HIS D O 1 ATOM 9504 C CB . HIS D 4 227 ? -64.772 73.486 -40.001 1.00 272.21 ? 208 HIS D CB 1 ATOM 9505 C CG . HIS D 4 227 ? -65.648 72.554 -39.223 1.00 271.57 ? 208 HIS D CG 1 ATOM 9506 N ND1 . HIS D 4 227 ? -66.886 72.146 -39.671 1.00 271.18 ? 208 HIS D ND1 1 ATOM 9507 C CD2 . HIS D 4 227 ? -65.467 71.956 -38.022 1.00 265.65 ? 208 HIS D CD2 1 ATOM 9508 C CE1 . HIS D 4 227 ? -67.429 71.335 -38.780 1.00 259.36 ? 208 HIS D CE1 1 ATOM 9509 N NE2 . HIS D 4 227 ? -66.588 71.202 -37.771 1.00 261.25 ? 208 HIS D NE2 1 ATOM 9510 N N . LYS D 4 228 ? -63.963 70.721 -42.005 1.00 275.29 ? 209 LYS D N 1 ATOM 9511 C CA . LYS D 4 228 ? -64.394 69.882 -43.125 1.00 265.24 ? 209 LYS D CA 1 ATOM 9512 C C . LYS D 4 228 ? -65.909 69.628 -43.271 1.00 275.00 ? 209 LYS D C 1 ATOM 9513 O O . LYS D 4 228 ? -66.458 69.843 -44.352 1.00 273.18 ? 209 LYS D O 1 ATOM 9514 C CB . LYS D 4 228 ? -63.610 68.560 -43.148 1.00 242.90 ? 209 LYS D CB 1 ATOM 9515 N N . PRO D 4 229 ? -66.586 69.163 -42.199 1.00 280.26 ? 210 PRO D N 1 ATOM 9516 C CA . PRO D 4 229 ? -67.995 68.778 -42.376 1.00 273.82 ? 210 PRO D CA 1 ATOM 9517 C C . PRO D 4 229 ? -68.920 69.923 -42.788 1.00 281.89 ? 210 PRO D C 1 ATOM 9518 O O . PRO D 4 229 ? -69.762 69.735 -43.666 1.00 279.88 ? 210 PRO D O 1 ATOM 9519 C CB . PRO D 4 229 ? -68.395 68.264 -40.989 1.00 247.26 ? 210 PRO D CB 1 ATOM 9520 C CG . PRO D 4 229 ? -67.114 67.884 -40.335 1.00 250.45 ? 210 PRO D CG 1 ATOM 9521 C CD . PRO D 4 229 ? -66.125 68.890 -40.825 1.00 271.46 ? 210 PRO D CD 1 ATOM 9522 N N . SER D 4 230 ? -68.773 71.086 -42.161 1.00 285.55 ? 211 SER D N 1 ATOM 9523 C CA . SER D 4 230 ? -69.635 72.224 -42.468 1.00 276.44 ? 211 SER D CA 1 ATOM 9524 C C . SER D 4 230 ? -69.006 73.179 -43.480 1.00 289.79 ? 211 SER D C 1 ATOM 9525 O O . SER D 4 230 ? -69.629 74.164 -43.880 1.00 287.61 ? 211 SER D O 1 ATOM 9526 C CB . SER D 4 230 ? -70.008 72.979 -41.190 1.00 257.38 ? 211 SER D CB 1 ATOM 9527 O OG . SER D 4 230 ? -68.854 73.443 -40.514 1.00 271.74 ? 211 SER D OG 1 ATOM 9528 N N . ASN D 4 231 ? -67.775 72.878 -43.886 1.00 297.18 ? 212 ASN D N 1 ATOM 9529 C CA . ASN D 4 231 ? -67.053 73.684 -44.873 1.00 279.38 ? 212 ASN D CA 1 ATOM 9530 C C . ASN D 4 231 ? -66.924 75.156 -44.479 1.00 279.53 ? 212 ASN D C 1 ATOM 9531 O O . ASN D 4 231 ? -67.543 76.026 -45.092 1.00 274.81 ? 212 ASN D O 1 ATOM 9532 C CB . ASN D 4 231 ? -67.696 73.552 -46.257 1.00 258.21 ? 212 ASN D CB 1 ATOM 9533 C CG . ASN D 4 231 ? -67.737 72.117 -46.745 1.00 250.40 ? 212 ASN D CG 1 ATOM 9534 O OD1 . ASN D 4 231 ? -66.801 71.640 -47.387 1.00 220.43 ? 212 ASN D OD1 1 ATOM 9535 N ND2 . ASN D 4 231 ? -68.826 71.420 -46.442 1.00 265.32 ? 212 ASN D ND2 1 ATOM 9536 N N . THR D 4 232 ? -66.119 75.430 -43.456 1.00 280.52 ? 213 THR D N 1 ATOM 9537 C CA . THR D 4 232 ? -65.981 76.790 -42.940 1.00 270.00 ? 213 THR D CA 1 ATOM 9538 C C . THR D 4 232 ? -64.532 77.177 -42.641 1.00 263.40 ? 213 THR D C 1 ATOM 9539 O O . THR D 4 232 ? -63.800 76.434 -41.987 1.00 269.58 ? 213 THR D O 1 ATOM 9540 C CB . THR D 4 232 ? -66.829 76.990 -41.666 1.00 259.68 ? 213 THR D CB 1 ATOM 9541 O OG1 . THR D 4 232 ? -68.205 76.715 -41.956 1.00 260.72 ? 213 THR D OG1 1 ATOM 9542 C CG2 . THR D 4 232 ? -66.701 78.415 -41.145 1.00 241.59 ? 213 THR D CG2 1 ATOM 9543 N N . LYS D 4 233 ? -64.131 78.349 -43.130 1.00 251.43 ? 214 LYS D N 1 ATOM 9544 C CA . LYS D 4 233 ? -62.817 78.911 -42.844 1.00 243.40 ? 214 LYS D CA 1 ATOM 9545 C C . LYS D 4 233 ? -62.986 80.375 -42.450 1.00 236.30 ? 214 LYS D C 1 ATOM 9546 O O . LYS D 4 233 ? -63.569 81.160 -43.196 1.00 233.92 ? 214 LYS D O 1 ATOM 9547 C CB . LYS D 4 233 ? -61.907 78.807 -44.074 1.00 237.08 ? 214 LYS D CB 1 ATOM 9548 C CG . LYS D 4 233 ? -60.406 78.702 -43.776 1.00 243.77 ? 214 LYS D CG 1 ATOM 9549 C CD . LYS D 4 233 ? -59.827 79.966 -43.143 1.00 252.99 ? 214 LYS D CD 1 ATOM 9550 C CE . LYS D 4 233 ? -59.628 81.077 -44.161 1.00 248.25 ? 214 LYS D CE 1 ATOM 9551 N NZ . LYS D 4 233 ? -58.431 80.835 -45.016 1.00 248.77 ? 214 LYS D NZ 1 ATOM 9552 N N . VAL D 4 234 ? -62.480 80.739 -41.277 1.00 234.55 ? 215 VAL D N 1 ATOM 9553 C CA . VAL D 4 234 ? -62.475 82.136 -40.859 1.00 230.41 ? 215 VAL D CA 1 ATOM 9554 C C . VAL D 4 234 ? -61.060 82.577 -40.501 1.00 239.61 ? 215 VAL D C 1 ATOM 9555 O O . VAL D 4 234 ? -60.480 82.102 -39.524 1.00 241.05 ? 215 VAL D O 1 ATOM 9556 C CB . VAL D 4 234 ? -63.411 82.379 -39.660 1.00 219.22 ? 215 VAL D CB 1 ATOM 9557 C CG1 . VAL D 4 234 ? -63.335 83.832 -39.214 1.00 217.26 ? 215 VAL D CG1 1 ATOM 9558 C CG2 . VAL D 4 234 ? -64.842 82.000 -40.013 1.00 211.28 ? 215 VAL D CG2 1 ATOM 9559 N N . ASP D 4 235 ? -60.511 83.490 -41.297 1.00 244.64 ? 216 ASP D N 1 ATOM 9560 C CA . ASP D 4 235 ? -59.158 83.988 -41.077 1.00 263.42 ? 216 ASP D CA 1 ATOM 9561 C C . ASP D 4 235 ? -59.177 85.304 -40.312 1.00 263.93 ? 216 ASP D C 1 ATOM 9562 O O . ASP D 4 235 ? -59.861 86.250 -40.700 1.00 256.58 ? 216 ASP D O 1 ATOM 9563 C CB . ASP D 4 235 ? -58.420 84.162 -42.406 1.00 267.96 ? 216 ASP D CB 1 ATOM 9564 C CG . ASP D 4 235 ? -57.351 83.109 -42.621 1.00 262.70 ? 216 ASP D CG 1 ATOM 9565 O OD1 . ASP D 4 235 ? -57.437 82.036 -41.987 1.00 271.62 ? 216 ASP D OD1 1 ATOM 9566 O OD2 . ASP D 4 235 ? -56.427 83.351 -43.426 1.00 240.65 ? 216 ASP D OD2 1 ATOM 9567 N N . LYS D 4 236 ? -58.421 85.356 -39.221 1.00 268.63 ? 217 LYS D N 1 ATOM 9568 C CA . LYS D 4 236 ? -58.378 86.543 -38.380 1.00 264.11 ? 217 LYS D CA 1 ATOM 9569 C C . LYS D 4 236 ? -56.942 87.006 -38.158 1.00 274.25 ? 217 LYS D C 1 ATOM 9570 O O . LYS D 4 236 ? -56.126 86.281 -37.590 1.00 290.07 ? 217 LYS D O 1 ATOM 9571 C CB . LYS D 4 236 ? -59.063 86.268 -37.039 1.00 253.97 ? 217 LYS D CB 1 ATOM 9572 C CG . LYS D 4 236 ? -60.437 85.612 -37.161 1.00 256.73 ? 217 LYS D CG 1 ATOM 9573 C CD . LYS D 4 236 ? -61.592 86.593 -36.957 1.00 256.64 ? 217 LYS D CD 1 ATOM 9574 C CE . LYS D 4 236 ? -61.785 87.541 -38.136 1.00 244.54 ? 217 LYS D CE 1 ATOM 9575 N NZ . LYS D 4 236 ? -60.880 88.724 -38.083 1.00 241.24 ? 217 LYS D NZ 1 ATOM 9576 N N . ARG D 4 237 ? -56.639 88.217 -38.615 1.00 271.37 ? 218 ARG D N 1 ATOM 9577 C CA . ARG D 4 237 ? -55.308 88.789 -38.451 1.00 274.37 ? 218 ARG D CA 1 ATOM 9578 C C . ARG D 4 237 ? -55.061 89.150 -36.992 1.00 276.90 ? 218 ARG D C 1 ATOM 9579 O O . ARG D 4 237 ? -56.002 89.447 -36.255 1.00 273.38 ? 218 ARG D O 1 ATOM 9580 C CB . ARG D 4 237 ? -55.148 90.016 -39.334 1.00 253.93 ? 218 ARG D CB 1 ATOM 9581 N N . VAL D 4 238 ? -53.800 89.123 -36.573 1.00 279.07 ? 219 VAL D N 1 ATOM 9582 C CA . VAL D 4 238 ? -53.475 89.501 -35.205 1.00 278.29 ? 219 VAL D CA 1 ATOM 9583 C C . VAL D 4 238 ? -52.673 90.797 -35.173 1.00 271.76 ? 219 VAL D C 1 ATOM 9584 O O . VAL D 4 238 ? -51.480 90.816 -35.478 1.00 254.50 ? 219 VAL D O 1 ATOM 9585 C CB . VAL D 4 238 ? -52.656 88.400 -34.505 1.00 270.72 ? 219 VAL D CB 1 ATOM 9586 C CG1 . VAL D 4 238 ? -52.398 88.771 -33.054 1.00 269.00 ? 219 VAL D CG1 1 ATOM 9587 C CG2 . VAL D 4 238 ? -53.373 87.063 -34.600 1.00 270.13 ? 219 VAL D CG2 1 ATOM 9588 N N . GLU D 4 239 ? -53.348 91.878 -34.801 1.00 275.68 ? 220 GLU D N 1 ATOM 9589 C CA . GLU D 4 239 ? -52.710 93.165 -34.548 1.00 256.15 ? 220 GLU D CA 1 ATOM 9590 C C . GLU D 4 239 ? -52.980 93.622 -33.117 1.00 253.83 ? 220 GLU D C 1 ATOM 9591 O O . GLU D 4 239 ? -54.137 93.807 -32.740 1.00 237.48 ? 220 GLU D O 1 ATOM 9592 C CB . GLU D 4 239 ? -53.162 94.214 -35.565 1.00 239.86 ? 220 GLU D CB 1 ATOM 9593 C CG . GLU D 4 239 ? -52.742 93.892 -36.993 1.00 223.99 ? 220 GLU D CG 1 ATOM 9594 C CD . GLU D 4 239 ? -52.983 95.040 -37.951 1.00 200.89 ? 220 GLU D CD 1 ATOM 9595 O OE1 . GLU D 4 239 ? -53.288 96.156 -37.480 1.00 196.88 ? 220 GLU D OE1 1 ATOM 9596 O OE2 . GLU D 4 239 ? -52.865 94.826 -39.176 1.00 202.25 ? 220 GLU D OE2 1 ATOM 9597 N N . PRO D 4 240 ? -51.917 93.784 -32.312 1.00 257.75 ? 221 PRO D N 1 ATOM 9598 C CA . PRO D 4 240 ? -52.054 94.185 -30.906 1.00 258.42 ? 221 PRO D CA 1 ATOM 9599 C C . PRO D 4 240 ? -52.897 95.448 -30.739 1.00 254.02 ? 221 PRO D C 1 ATOM 9600 O O . PRO D 4 240 ? -52.663 96.444 -31.425 1.00 251.09 ? 221 PRO D O 1 ATOM 9601 C CB . PRO D 4 240 ? -50.609 94.465 -30.485 1.00 243.06 ? 221 PRO D CB 1 ATOM 9602 C CG . PRO D 4 240 ? -49.785 93.614 -31.386 1.00 224.27 ? 221 PRO D CG 1 ATOM 9603 C CD . PRO D 4 240 ? -50.508 93.602 -32.702 1.00 234.53 ? 221 PRO D CD 1 ATOM 9604 N N . LYS D 4 241 ? -53.869 95.398 -29.833 1.00 244.88 ? 222 LYS D N 1 ATOM 9605 C CA . LYS D 4 241 ? -54.770 96.523 -29.607 1.00 240.01 ? 222 LYS D CA 1 ATOM 9606 C C . LYS D 4 241 ? -54.622 97.084 -28.198 1.00 254.39 ? 222 LYS D C 1 ATOM 9607 O O . LYS D 4 241 ? -53.808 96.604 -27.409 1.00 246.90 ? 222 LYS D O 1 ATOM 9608 C CB . LYS D 4 241 ? -56.222 96.106 -29.853 1.00 214.18 ? 222 LYS D CB 1 ATOM 9609 C CG . LYS D 4 241 ? -56.547 95.786 -31.304 1.00 194.15 ? 222 LYS D CG 1 ATOM 9610 C CD . LYS D 4 241 ? -56.379 97.010 -32.190 1.00 182.30 ? 222 LYS D CD 1 ATOM 9611 C CE . LYS D 4 241 ? -56.800 96.723 -33.623 1.00 160.36 ? 222 LYS D CE 1 ATOM 9612 N NZ . LYS D 4 241 ? -58.245 96.377 -33.723 1.00 113.27 ? 222 LYS D NZ 1 ATOM 9613 N N . SER D 4 242 ? -55.417 98.104 -27.888 1.00 262.80 ? 223 SER D N 1 ATOM 9614 C CA . SER D 4 242 ? -55.368 98.744 -26.579 1.00 267.21 ? 223 SER D CA 1 ATOM 9615 C C . SER D 4 242 ? -56.092 97.920 -25.519 1.00 257.98 ? 223 SER D C 1 ATOM 9616 O O . SER D 4 242 ? -57.064 97.224 -25.813 1.00 256.00 ? 223 SER D O 1 ATOM 9617 C CB . SER D 4 242 ? -55.966 100.151 -26.646 1.00 264.81 ? 223 SER D CB 1 ATOM 9618 O OG . SER D 4 242 ? -55.218 100.983 -27.517 1.00 274.31 ? 223 SER D OG 1 ATOM 9619 N N . CYS D 4 243 ? -55.606 98.004 -24.284 1.00 247.82 ? 224 CYS D N 1 ATOM 9620 C CA . CYS D 4 243 ? -56.224 97.310 -23.161 1.00 240.77 ? 224 CYS D CA 1 ATOM 9621 C C . CYS D 4 243 ? -56.355 98.249 -21.967 1.00 227.52 ? 224 CYS D C 1 ATOM 9622 O O . CYS D 4 243 ? -55.735 99.313 -21.932 1.00 227.93 ? 224 CYS D O 1 ATOM 9623 C CB . CYS D 4 243 ? -55.410 96.073 -22.775 1.00 243.79 ? 224 CYS D CB 1 ATOM 9624 S SG . CYS D 4 243 ? -55.282 94.826 -24.078 1.00 252.79 ? 224 CYS D SG 1 ATOM 9625 N N . ASP D 4 244 ? -57.166 97.855 -20.991 1.00 217.94 ? 225 ASP D N 1 ATOM 9626 C CA . ASP D 4 244 ? -57.395 98.679 -19.810 1.00 201.46 ? 225 ASP D CA 1 ATOM 9627 C C . ASP D 4 244 ? -57.060 97.920 -18.531 1.00 178.14 ? 225 ASP D C 1 ATOM 9628 O O . ASP D 4 244 ? -56.748 98.523 -17.505 1.00 154.36 ? 225 ASP D O 1 ATOM 9629 C CB . ASP D 4 244 ? -58.845 99.166 -19.770 1.00 221.78 ? 225 ASP D CB 1 ATOM 9630 C CG . ASP D 4 244 ? -59.235 99.937 -21.016 1.00 216.53 ? 225 ASP D CG 1 ATOM 9631 O OD1 . ASP D 4 244 ? -58.360 100.609 -21.601 1.00 216.94 ? 225 ASP D OD1 1 ATOM 9632 O OD2 . ASP D 4 244 ? -60.418 99.869 -21.411 1.00 202.35 ? 225 ASP D OD2 1 HETATM 9633 C C1 . NAG E 5 . ? -54.326 -13.757 -33.253 1.00 46.53 ? 901 NAG A C1 1 HETATM 9634 C C2 . NAG E 5 . ? -53.264 -14.644 -33.891 1.00 43.69 ? 901 NAG A C2 1 HETATM 9635 C C3 . NAG E 5 . ? -53.820 -16.047 -34.098 1.00 44.52 ? 901 NAG A C3 1 HETATM 9636 C C4 . NAG E 5 . ? -54.321 -16.611 -32.776 1.00 43.10 ? 901 NAG A C4 1 HETATM 9637 C C5 . NAG E 5 . ? -55.239 -15.621 -32.061 1.00 50.07 ? 901 NAG A C5 1 HETATM 9638 C C6 . NAG E 5 . ? -55.525 -16.105 -30.642 1.00 60.63 ? 901 NAG A C6 1 HETATM 9639 C C7 . NAG E 5 . ? -51.495 -13.786 -35.301 1.00 53.11 ? 901 NAG A C7 1 HETATM 9640 C C8 . NAG E 5 . ? -50.877 -14.162 -36.615 1.00 54.95 ? 901 NAG A C8 1 HETATM 9641 N N2 . NAG E 5 . ? -52.783 -14.078 -35.137 1.00 46.58 ? 901 NAG A N2 1 HETATM 9642 O O3 . NAG E 5 . ? -52.818 -16.889 -34.619 1.00 43.01 ? 901 NAG A O3 1 HETATM 9643 O O4 . NAG E 5 . ? -55.005 -17.825 -33.002 1.00 35.28 ? 901 NAG A O4 1 HETATM 9644 O O5 . NAG E 5 . ? -54.685 -14.318 -32.006 1.00 52.76 ? 901 NAG A O5 1 HETATM 9645 O O6 . NAG E 5 . ? -55.562 -15.011 -29.749 1.00 64.69 ? 901 NAG A O6 1 HETATM 9646 O O7 . NAG E 5 . ? -50.819 -13.236 -34.434 1.00 54.38 ? 901 NAG A O7 1 HETATM 9647 C C1 . NAG F 5 . ? -12.473 -14.711 -36.956 1.00 92.06 ? 902 NAG A C1 1 HETATM 9648 C C2 . NAG F 5 . ? -12.788 -14.485 -38.434 1.00 86.46 ? 902 NAG A C2 1 HETATM 9649 C C3 . NAG F 5 . ? -13.677 -15.592 -38.987 1.00 84.61 ? 902 NAG A C3 1 HETATM 9650 C C4 . NAG F 5 . ? -13.082 -16.956 -38.672 1.00 80.48 ? 902 NAG A C4 1 HETATM 9651 C C5 . NAG F 5 . ? -12.794 -17.073 -37.181 1.00 87.39 ? 902 NAG A C5 1 HETATM 9652 C C6 . NAG F 5 . ? -12.114 -18.402 -36.866 1.00 86.91 ? 902 NAG A C6 1 HETATM 9653 C C7 . NAG F 5 . ? -12.879 -12.301 -39.484 1.00 85.40 ? 902 NAG A C7 1 HETATM 9654 C C8 . NAG F 5 . ? -13.020 -10.851 -39.128 1.00 83.11 ? 902 NAG A C8 1 HETATM 9655 N N2 . NAG F 5 . ? -13.401 -13.184 -38.635 1.00 85.16 ? 902 NAG A N2 1 HETATM 9656 O O3 . NAG F 5 . ? -13.795 -15.449 -40.384 1.00 95.64 ? 902 NAG A O3 1 HETATM 9657 O O4 . NAG F 5 . ? -13.976 -17.974 -39.069 1.00 76.15 ? 902 NAG A O4 1 HETATM 9658 O O5 . NAG F 5 . ? -11.961 -16.015 -36.752 1.00 93.15 ? 902 NAG A O5 1 HETATM 9659 O O6 . NAG F 5 . ? -11.596 -18.366 -35.554 1.00 84.35 ? 902 NAG A O6 1 HETATM 9660 O O7 . NAG F 5 . ? -12.303 -12.633 -40.518 1.00 84.67 ? 902 NAG A O7 1 HETATM 9661 C C1 . NAG G 5 . ? -2.676 -33.450 -4.217 1.00 99.18 ? 903 NAG A C1 1 HETATM 9662 C C2 . NAG G 5 . ? -2.276 -34.612 -3.308 1.00 100.68 ? 903 NAG A C2 1 HETATM 9663 C C3 . NAG G 5 . ? -0.897 -35.165 -3.650 1.00 99.47 ? 903 NAG A C3 1 HETATM 9664 C C4 . NAG G 5 . ? -0.744 -35.377 -5.150 1.00 103.40 ? 903 NAG A C4 1 HETATM 9665 C C5 . NAG G 5 . ? -1.136 -34.122 -5.919 1.00 97.24 ? 903 NAG A C5 1 HETATM 9666 C C6 . NAG G 5 . ? -1.070 -34.378 -7.420 1.00 90.92 ? 903 NAG A C6 1 HETATM 9667 C C7 . NAG G 5 . ? -3.141 -34.730 -1.031 1.00 111.29 ? 903 NAG A C7 1 HETATM 9668 C C8 . NAG G 5 . ? -3.042 -34.234 0.382 1.00 110.72 ? 903 NAG A C8 1 HETATM 9669 N N2 . NAG G 5 . ? -2.305 -34.191 -1.918 1.00 106.74 ? 903 NAG A N2 1 HETATM 9670 O O3 . NAG G 5 . ? -0.709 -36.397 -2.988 1.00 93.54 ? 903 NAG A O3 1 HETATM 9671 O O4 . NAG G 5 . ? 0.595 -35.714 -5.445 1.00 104.38 ? 903 NAG A O4 1 HETATM 9672 O O5 . NAG G 5 . ? -2.449 -33.725 -5.586 1.00 98.78 ? 903 NAG A O5 1 HETATM 9673 O O6 . NAG G 5 . ? -2.294 -34.007 -8.014 1.00 88.64 ? 903 NAG A O6 1 HETATM 9674 O O7 . NAG G 5 . ? -3.967 -35.592 -1.328 1.00 110.64 ? 903 NAG A O7 1 HETATM 9675 C C1 . NAG H 5 . ? -73.764 7.022 -17.498 1.00 67.61 ? 800 NAG B C1 1 HETATM 9676 C C2 . NAG H 5 . ? -73.693 6.617 -18.970 1.00 75.16 ? 800 NAG B C2 1 HETATM 9677 C C3 . NAG H 5 . ? -73.859 7.823 -19.902 1.00 85.28 ? 800 NAG B C3 1 HETATM 9678 C C4 . NAG H 5 . ? -75.034 8.721 -19.503 1.00 85.54 ? 800 NAG B C4 1 HETATM 9679 C C5 . NAG H 5 . ? -75.060 8.905 -17.991 1.00 79.63 ? 800 NAG B C5 1 HETATM 9680 C C6 . NAG H 5 . ? -76.349 9.561 -17.537 1.00 87.67 ? 800 NAG B C6 1 HETATM 9681 C C7 . NAG H 5 . ? -72.509 4.671 -19.772 1.00 74.80 ? 800 NAG B C7 1 HETATM 9682 C C8 . NAG H 5 . ? -71.948 4.493 -21.151 1.00 69.03 ? 800 NAG B C8 1 HETATM 9683 N N2 . NAG H 5 . ? -72.468 5.900 -19.263 1.00 75.51 ? 800 NAG B N2 1 HETATM 9684 O O3 . NAG H 5 . ? -74.049 7.352 -21.218 1.00 91.09 ? 800 NAG B O3 1 HETATM 9685 O O4 . NAG H 5 . ? -74.949 9.984 -20.147 1.00 86.79 ? 800 NAG B O4 1 HETATM 9686 O O5 . NAG H 5 . ? -75.013 7.648 -17.370 1.00 78.59 ? 800 NAG B O5 1 HETATM 9687 O O6 . NAG H 5 . ? -76.961 8.785 -16.527 1.00 85.42 ? 800 NAG B O6 1 HETATM 9688 O O7 . NAG H 5 . ? -72.982 3.712 -19.165 1.00 74.08 ? 800 NAG B O7 1 HETATM 9689 C C1 . NAG I 5 . ? -75.826 10.078 -21.296 1.00 86.98 ? 801 NAG B C1 1 HETATM 9690 C C2 . NAG I 5 . ? -76.921 11.120 -21.032 1.00 91.66 ? 801 NAG B C2 1 HETATM 9691 C C3 . NAG I 5 . ? -77.709 11.516 -22.278 1.00 96.01 ? 801 NAG B C3 1 HETATM 9692 C C4 . NAG I 5 . ? -76.838 11.702 -23.510 1.00 101.10 ? 801 NAG B C4 1 HETATM 9693 C C5 . NAG I 5 . ? -75.874 10.531 -23.658 1.00 96.66 ? 801 NAG B C5 1 HETATM 9694 C C6 . NAG I 5 . ? -74.937 10.761 -24.841 1.00 103.53 ? 801 NAG B C6 1 HETATM 9695 C C7 . NAG I 5 . ? -78.520 11.515 -19.247 1.00 83.81 ? 801 NAG B C7 1 HETATM 9696 C C8 . NAG I 5 . ? -79.576 10.945 -18.345 1.00 78.55 ? 801 NAG B C8 1 HETATM 9697 N N2 . NAG I 5 . ? -77.873 10.659 -20.038 1.00 90.54 ? 801 NAG B N2 1 HETATM 9698 O O3 . NAG I 5 . ? -78.412 12.713 -22.029 1.00 95.85 ? 801 NAG B O3 1 HETATM 9699 O O4 . NAG I 5 . ? -77.700 11.796 -24.627 1.00 104.95 ? 801 NAG B O4 1 HETATM 9700 O O5 . NAG I 5 . ? -75.104 10.374 -22.480 1.00 87.57 ? 801 NAG B O5 1 HETATM 9701 O O6 . NAG I 5 . ? -74.128 9.624 -25.049 1.00 106.88 ? 801 NAG B O6 1 HETATM 9702 O O7 . NAG I 5 . ? -78.287 12.722 -19.238 1.00 81.23 ? 801 NAG B O7 1 HETATM 9703 C C1 . BMA J 6 . ? -77.649 13.107 -25.228 1.00 109.10 ? 802 BMA B C1 1 HETATM 9704 C C2 . BMA J 6 . ? -77.371 12.910 -26.735 1.00 116.95 ? 802 BMA B C2 1 HETATM 9705 C C3 . BMA J 6 . ? -77.534 14.225 -27.533 1.00 121.71 ? 802 BMA B C3 1 HETATM 9706 C C4 . BMA J 6 . ? -78.764 15.041 -27.086 1.00 125.14 ? 802 BMA B C4 1 HETATM 9707 C C5 . BMA J 6 . ? -78.763 15.204 -25.561 1.00 113.59 ? 802 BMA B C5 1 HETATM 9708 C C6 . BMA J 6 . ? -79.958 16.001 -25.044 1.00 112.53 ? 802 BMA B C6 1 HETATM 9709 O O2 . BMA J 6 . ? -78.292 11.974 -27.284 1.00 115.18 ? 802 BMA B O2 1 HETATM 9710 O O3 . BMA J 6 . ? -77.575 13.983 -28.953 1.00 126.09 ? 802 BMA B O3 1 HETATM 9711 O O4 . BMA J 6 . ? -78.743 16.323 -27.695 1.00 131.91 ? 802 BMA B O4 1 HETATM 9712 O O5 . BMA J 6 . ? -78.804 13.889 -24.974 1.00 105.58 ? 802 BMA B O5 1 HETATM 9713 O O6 . BMA J 6 . ? -80.083 17.194 -25.815 1.00 110.39 ? 802 BMA B O6 1 HETATM 9714 C C1 . MAN K 7 . ? -76.350 13.352 -29.379 1.00 128.76 ? 803 MAN B C1 1 HETATM 9715 C C2 . MAN K 7 . ? -75.608 14.276 -30.337 1.00 134.85 ? 803 MAN B C2 1 HETATM 9716 C C3 . MAN K 7 . ? -76.456 14.491 -31.584 1.00 135.08 ? 803 MAN B C3 1 HETATM 9717 C C4 . MAN K 7 . ? -76.854 13.145 -32.183 1.00 134.59 ? 803 MAN B C4 1 HETATM 9718 C C5 . MAN K 7 . ? -77.452 12.224 -31.122 1.00 126.28 ? 803 MAN B C5 1 HETATM 9719 C C6 . MAN K 7 . ? -77.711 10.835 -31.694 1.00 126.24 ? 803 MAN B C6 1 HETATM 9720 O O2 . MAN K 7 . ? -74.364 13.713 -30.690 1.00 137.64 ? 803 MAN B O2 1 HETATM 9721 O O3 . MAN K 7 . ? -75.731 15.241 -32.534 1.00 130.89 ? 803 MAN B O3 1 HETATM 9722 O O4 . MAN K 7 . ? -77.796 13.348 -33.212 1.00 136.58 ? 803 MAN B O4 1 HETATM 9723 O O5 . MAN K 7 . ? -76.574 12.115 -30.022 1.00 125.13 ? 803 MAN B O5 1 HETATM 9724 O O6 . MAN K 7 . ? -77.977 9.931 -30.644 1.00 123.37 ? 803 MAN B O6 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 MET 1 1 ? ? ? A . n A 1 2 PHE 2 2 ? ? ? A . n A 1 3 ALA 3 3 ? ? ? A . n A 1 4 LEU 4 4 ? ? ? A . n A 1 5 VAL 5 5 ? ? ? A . n A 1 6 LEU 6 6 ? ? ? A . n A 1 7 ALA 7 7 ? ? ? A . n A 1 8 VAL 8 8 ? ? ? A . n A 1 9 VAL 9 9 ? ? ? A . n A 1 10 ILE 10 10 ? ? ? A . n A 1 11 LEU 11 11 ? ? ? A . n A 1 12 PRO 12 12 ? ? ? A . n A 1 13 LEU 13 13 ? ? ? A . n A 1 14 TRP 14 14 ? ? ? A . n A 1 15 THR 15 15 ? ? ? A . n A 1 16 THR 16 16 ? ? ? A . n A 1 17 ALA 17 17 ? ? ? A . n A 1 18 ASN 18 18 ? ? ? A . n A 1 19 LYS 19 19 ? ? ? A . n A 1 20 SER 20 20 ? ? ? A . n A 1 21 TYR 21 21 ? ? ? A . n A 1 22 VAL 22 22 ? ? ? A . n A 1 23 THR 23 23 ? ? ? A . n A 1 24 PRO 24 24 ? ? ? A . n A 1 25 THR 25 25 ? ? ? A . n A 1 26 PRO 26 26 ? ? ? A . n A 1 27 ALA 27 27 ? ? ? A . n A 1 28 THR 28 28 ? ? ? A . n A 1 29 ARG 29 29 ? ? ? A . n A 1 30 SER 30 30 ? ? ? A . n A 1 31 ILE 31 31 ? ? ? A . n A 1 32 GLY 32 32 ? ? ? A . n A 1 33 HIS 33 33 ? ? ? A . n A 1 34 MET 34 34 ? ? ? A . n A 1 35 SER 35 35 ? ? ? A . n A 1 36 ALA 36 36 36 ALA ALA A . n A 1 37 LEU 37 37 37 LEU LEU A . n A 1 38 LEU 38 38 38 LEU LEU A . n A 1 39 ARG 39 39 39 ARG ALA A . n A 1 40 GLU 40 40 40 GLU GLU A . n A 1 41 TYR 41 41 41 TYR TYR A . n A 1 42 SER 42 42 42 SER SER A . n A 1 43 ASP 43 43 43 ASP ASP A . n A 1 44 ARG 44 44 44 ARG ALA A . n A 1 45 ASN 45 45 45 ASN ASN A . n A 1 46 MET 46 46 46 MET MET A . n A 1 47 SER 47 47 47 SER SER A . n A 1 48 LEU 48 48 48 LEU ALA A . n A 1 49 LYS 49 49 49 LYS ALA A . n A 1 50 LEU 50 50 50 LEU LEU A . n A 1 51 GLU 51 51 51 GLU ALA A . n A 1 52 ALA 52 52 52 ALA ALA A . n A 1 53 PHE 53 53 53 PHE PHE A . n A 1 54 TYR 54 54 54 TYR TYR A . n A 1 55 PRO 55 55 55 PRO PRO A . n A 1 56 THR 56 56 56 THR THR A . n A 1 57 GLY 57 57 57 GLY GLY A . n A 1 58 PHE 58 58 58 PHE ALA A . n A 1 59 ASP 59 59 59 ASP ASP A . n A 1 60 GLU 60 60 60 GLU GLU A . n A 1 61 GLU 61 61 61 GLU ALA A . n A 1 62 LEU 62 62 62 LEU ALA A . n A 1 63 ILE 63 63 63 ILE ALA A . n A 1 64 LYS 64 64 64 LYS ALA A . n A 1 65 SER 65 65 65 SER SER A . n A 1 66 LEU 66 66 66 LEU ALA A . n A 1 67 HIS 67 67 67 HIS HIS A . n A 1 68 TRP 68 68 68 TRP TRP A . n A 1 69 GLY 69 69 69 GLY GLY A . n A 1 70 ASN 70 70 70 ASN ASN A . n A 1 71 ASP 71 71 71 ASP ASP A . n A 1 72 ARG 72 72 72 ARG ARG A . n A 1 73 LYS 73 73 73 LYS LYS A . n A 1 74 HIS 74 74 74 HIS HIS A . n A 1 75 VAL 75 75 75 VAL VAL A . n A 1 76 PHE 76 76 76 PHE PHE A . n A 1 77 LEU 77 77 77 LEU LEU A . n A 1 78 VAL 78 78 78 VAL VAL A . n A 1 79 ILE 79 79 79 ILE ILE A . n A 1 80 VAL 80 80 80 VAL VAL A . n A 1 81 LYS 81 81 81 LYS LYS A . n A 1 82 VAL 82 82 82 VAL VAL A . n A 1 83 ASN 83 83 83 ASN ASN A . n A 1 84 PRO 84 84 84 PRO PRO A . n A 1 85 THR 85 85 85 THR ALA A . n A 1 86 THR 86 86 86 THR ALA A . n A 1 87 HIS 87 87 87 HIS ALA A . n A 1 88 GLU 88 88 88 GLU ALA A . n A 1 89 GLY 89 89 89 GLY GLY A . n A 1 90 ASP 90 90 90 ASP ASP A . n A 1 91 VAL 91 91 91 VAL VAL A . n A 1 92 GLY 92 92 92 GLY GLY A . n A 1 93 LEU 93 93 93 LEU LEU A . n A 1 94 VAL 94 94 94 VAL VAL A . n A 1 95 ILE 95 95 95 ILE ILE A . n A 1 96 PHE 96 96 96 PHE PHE A . n A 1 97 PRO 97 97 97 PRO PRO A . n A 1 98 LYS 98 98 98 LYS LYS A . n A 1 99 TYR 99 99 99 TYR TYR A . n A 1 100 LEU 100 100 100 LEU LEU A . n A 1 101 LEU 101 101 101 LEU LEU A . n A 1 102 SER 102 102 102 SER SER A . n A 1 103 PRO 103 103 103 PRO PRO A . n A 1 104 TYR 104 104 104 TYR ALA A . n A 1 105 HIS 105 105 ? ? ? A . n A 1 106 PHE 106 106 ? ? ? A . n A 1 107 LYS 107 107 ? ? ? A . n A 1 108 ALA 108 108 ? ? ? A . n A 1 109 GLU 109 109 ? ? ? A . n A 1 110 HIS 110 110 ? ? ? A . n A 1 111 ARG 111 111 ? ? ? A . n A 1 112 ALA 112 112 ? ? ? A . n A 1 113 PRO 113 113 ? ? ? A . n A 1 114 PHE 114 114 ? ? ? A . n A 1 115 PRO 115 115 ? ? ? A . n A 1 116 ALA 116 116 ? ? ? A . n A 1 117 GLY 117 117 ? ? ? A . n A 1 118 ARG 118 118 ? ? ? A . n A 1 119 PHE 119 119 119 PHE ALA A . n A 1 120 GLY 120 120 120 GLY GLY A . n A 1 121 PHE 121 121 121 PHE PHE A . n A 1 122 LEU 122 122 122 LEU LEU A . n A 1 123 SER 123 123 123 SER SER A . n A 1 124 HIS 124 124 124 HIS HIS A . n A 1 125 PRO 125 125 125 PRO PRO A . n A 1 126 VAL 126 126 126 VAL VAL A . n A 1 127 THR 127 127 127 THR THR A . n A 1 128 PRO 128 128 128 PRO PRO A . n A 1 129 ASP 129 129 129 ASP ASP A . n A 1 130 VAL 130 130 130 VAL VAL A . n A 1 131 SER 131 131 131 SER SER A . n A 1 132 PHE 132 132 132 PHE PHE A . n A 1 133 PHE 133 133 133 PHE PHE A . n A 1 134 ASP 134 134 134 ASP ASP A . n A 1 135 SER 135 135 135 SER SER A . n A 1 136 SER 136 136 136 SER SER A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 ALA 138 138 138 ALA ALA A . n A 1 139 PRO 139 139 139 PRO PRO A . n A 1 140 TYR 140 140 140 TYR TYR A . n A 1 141 LEU 141 141 141 LEU LEU A . n A 1 142 THR 142 142 142 THR THR A . n A 1 143 THR 143 143 143 THR THR A . n A 1 144 GLN 144 144 144 GLN GLN A . n A 1 145 HIS 145 145 145 HIS HIS A . n A 1 146 LEU 146 146 146 LEU LEU A . n A 1 147 VAL 147 147 147 VAL VAL A . n A 1 148 ALA 148 148 148 ALA ALA A . n A 1 149 PHE 149 149 149 PHE PHE A . n A 1 150 THR 150 150 150 THR THR A . n A 1 151 THR 151 151 151 THR THR A . n A 1 152 PHE 152 152 152 PHE PHE A . n A 1 153 PRO 153 153 153 PRO PRO A . n A 1 154 PRO 154 154 154 PRO PRO A . n A 1 155 ASN 155 155 155 ASN ASN A . n A 1 156 PRO 156 156 156 PRO PRO A . n A 1 157 LEU 157 157 157 LEU LEU A . n A 1 158 VAL 158 158 158 VAL VAL A . n A 1 159 TRP 159 159 159 TRP TRP A . n A 1 160 HIS 160 160 160 HIS HIS A . n A 1 161 LEU 161 161 161 LEU LEU A . n A 1 162 GLU 162 162 162 GLU GLU A . n A 1 163 ARG 163 163 163 ARG ARG A . n A 1 164 ALA 164 164 164 ALA ALA A . n A 1 165 GLU 165 165 165 GLU GLU A . n A 1 166 THR 166 166 166 THR THR A . n A 1 167 ALA 167 167 167 ALA ALA A . n A 1 168 ALA 168 168 168 ALA ALA A . n A 1 169 THR 169 169 169 THR THR A . n A 1 170 ALA 170 170 170 ALA ALA A . n A 1 171 GLU 171 171 171 GLU GLU A . n A 1 172 ARG 172 172 172 ARG ARG A . n A 1 173 PRO 173 173 173 PRO PRO A . n A 1 174 PHE 174 174 174 PHE PHE A . n A 1 175 GLY 175 175 175 GLY GLY A . n A 1 176 VAL 176 176 176 VAL VAL A . n A 1 177 SER 177 177 177 SER SER A . n A 1 178 LEU 178 178 178 LEU LEU A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 PRO 180 180 180 PRO PRO A . n A 1 181 ALA 181 181 181 ALA ALA A . n A 1 182 ARG 182 182 182 ARG ARG A . n A 1 183 PRO 183 183 183 PRO PRO A . n A 1 184 THR 184 184 184 THR THR A . n A 1 185 VAL 185 185 185 VAL VAL A . n A 1 186 PRO 186 186 186 PRO PRO A . n A 1 187 LYS 187 187 187 LYS ALA A . n A 1 188 ASN 188 188 188 ASN ALA A . n A 1 189 THR 189 189 189 THR ALA A . n A 1 190 ILE 190 190 190 ILE ILE A . n A 1 191 LEU 191 191 191 LEU LEU A . n A 1 192 GLU 192 192 192 GLU GLU A . n A 1 193 HIS 193 193 193 HIS ALA A . n A 1 194 LYS 194 194 194 LYS LYS A . n A 1 195 ALA 195 195 195 ALA ALA A . n A 1 196 HIS 196 196 196 HIS HIS A . n A 1 197 PHE 197 197 197 PHE PHE A . n A 1 198 ALA 198 198 198 ALA ALA A . n A 1 199 THR 199 199 199 THR THR A . n A 1 200 TRP 200 200 200 TRP TRP A . n A 1 201 ASP 201 201 201 ASP ASP A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 LEU 203 203 203 LEU LEU A . n A 1 204 ALA 204 204 204 ALA ALA A . n A 1 205 ARG 205 205 205 ARG ARG A . n A 1 206 HIS 206 206 206 HIS HIS A . n A 1 207 THR 207 207 207 THR THR A . n A 1 208 PHE 208 208 208 PHE PHE A . n A 1 209 PHE 209 209 209 PHE PHE A . n A 1 210 SER 210 210 210 SER SER A . n A 1 211 ALA 211 211 211 ALA ALA A . n A 1 212 GLU 212 212 212 GLU GLU A . n A 1 213 ALA 213 213 213 ALA ALA A . n A 1 214 ILE 214 214 214 ILE ILE A . n A 1 215 ILE 215 215 215 ILE ILE A . n A 1 216 THR 216 216 216 THR THR A . n A 1 217 ASN 217 217 217 ASN ASN A . n A 1 218 SER 218 218 218 SER SER A . n A 1 219 THR 219 219 219 THR THR A . n A 1 220 LEU 220 220 220 LEU LEU A . n A 1 221 ARG 221 221 221 ARG ARG A . n A 1 222 ILE 222 222 222 ILE ILE A . n A 1 223 HIS 223 223 223 HIS HIS A . n A 1 224 VAL 224 224 224 VAL VAL A . n A 1 225 PRO 225 225 225 PRO PRO A . n A 1 226 LEU 226 226 226 LEU LEU A . n A 1 227 PHE 227 227 227 PHE PHE A . n A 1 228 GLY 228 228 228 GLY GLY A . n A 1 229 SER 229 229 229 SER SER A . n A 1 230 VAL 230 230 230 VAL VAL A . n A 1 231 TRP 231 231 231 TRP TRP A . n A 1 232 PRO 232 232 232 PRO PRO A . n A 1 233 ILE 233 233 233 ILE ILE A . n A 1 234 ARG 234 234 234 ARG ARG A . n A 1 235 TYR 235 235 235 TYR TYR A . n A 1 236 TRP 236 236 236 TRP TRP A . n A 1 237 ALA 237 237 237 ALA ALA A . n A 1 238 THR 238 238 238 THR THR A . n A 1 239 GLY 239 239 239 GLY GLY A . n A 1 240 SER 240 240 240 SER SER A . n A 1 241 VAL 241 241 241 VAL VAL A . n A 1 242 LEU 242 242 242 LEU LEU A . n A 1 243 LEU 243 243 243 LEU LEU A . n A 1 244 THR 244 244 244 THR THR A . n A 1 245 SER 245 245 245 SER SER A . n A 1 246 ASP 246 246 246 ASP ASP A . n A 1 247 SER 247 247 247 SER SER A . n A 1 248 GLY 248 248 248 GLY GLY A . n A 1 249 ARG 249 249 249 ARG ARG A . n A 1 250 VAL 250 250 250 VAL VAL A . n A 1 251 GLU 251 251 251 GLU GLU A . n A 1 252 VAL 252 252 252 VAL VAL A . n A 1 253 ASN 253 253 253 ASN ASN A . n A 1 254 ILE 254 254 254 ILE ILE A . n A 1 255 GLY 255 255 255 GLY GLY A . n A 1 256 VAL 256 256 256 VAL VAL A . n A 1 257 GLY 257 257 257 GLY GLY A . n A 1 258 PHE 258 258 258 PHE PHE A . n A 1 259 MET 259 259 259 MET MET A . n A 1 260 SER 260 260 260 SER SER A . n A 1 261 SER 261 261 261 SER SER A . n A 1 262 LEU 262 262 262 LEU LEU A . n A 1 263 ILE 263 263 263 ILE ILE A . n A 1 264 SER 264 264 264 SER SER A . n A 1 265 LEU 265 265 265 LEU LEU A . n A 1 266 SER 266 266 266 SER SER A . n A 1 267 SER 267 267 267 SER SER A . n A 1 268 GLY 268 268 268 GLY GLY A . n A 1 269 LEU 269 269 269 LEU LEU A . n A 1 270 PRO 270 270 270 PRO PRO A . n A 1 271 ILE 271 271 271 ILE ILE A . n A 1 272 GLU 272 272 272 GLU GLU A . n A 1 273 LEU 273 273 273 LEU LEU A . n A 1 274 ILE 274 274 274 ILE ILE A . n A 1 275 VAL 275 275 275 VAL VAL A . n A 1 276 VAL 276 276 276 VAL VAL A . n A 1 277 PRO 277 277 277 PRO PRO A . n A 1 278 HIS 278 278 278 HIS HIS A . n A 1 279 THR 279 279 279 THR THR A . n A 1 280 VAL 280 280 280 VAL VAL A . n A 1 281 LYS 281 281 281 LYS LYS A . n A 1 282 LEU 282 282 282 LEU LEU A . n A 1 283 ASN 283 283 283 ASN ASN A . n A 1 284 ALA 284 284 284 ALA ALA A . n A 1 285 VAL 285 285 285 VAL VAL A . n A 1 286 THR 286 286 286 THR THR A . n A 1 287 SER 287 287 287 SER SER A . n A 1 288 ASP 288 288 288 ASP ASP A . n A 1 289 THR 289 289 289 THR THR A . n A 1 290 THR 290 290 290 THR THR A . n A 1 291 TRP 291 291 291 TRP TRP A . n A 1 292 PHE 292 292 292 PHE PHE A . n A 1 293 GLN 293 293 293 GLN ALA A . n A 1 294 LEU 294 294 294 LEU LEU A . n A 1 295 ASN 295 295 295 ASN ASN A . n A 1 296 PRO 296 296 296 PRO PRO A . n A 1 297 PRO 297 297 297 PRO PRO A . n A 1 298 GLY 298 298 298 GLY GLY A . n A 1 299 PRO 299 299 299 PRO PRO A . n A 1 300 ASP 300 300 300 ASP ASP A . n A 1 301 PRO 301 301 301 PRO PRO A . n A 1 302 GLY 302 302 302 GLY GLY A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 SER 304 304 304 SER SER A . n A 1 305 TYR 305 305 305 TYR TYR A . n A 1 306 ARG 306 306 306 ARG ARG A . n A 1 307 VAL 307 307 307 VAL VAL A . n A 1 308 TYR 308 308 308 TYR TYR A . n A 1 309 LEU 309 309 309 LEU LEU A . n A 1 310 LEU 310 310 310 LEU LEU A . n A 1 311 GLY 311 311 311 GLY GLY A . n A 1 312 ARG 312 312 312 ARG ARG A . n A 1 313 GLY 313 313 313 GLY GLY A . n A 1 314 LEU 314 314 314 LEU LEU A . n A 1 315 ASP 315 315 315 ASP ASP A . n A 1 316 MET 316 316 316 MET MET A . n A 1 317 ASN 317 317 317 ASN ASN A . n A 1 318 PHE 318 318 318 PHE PHE A . n A 1 319 SER 319 319 319 SER ALA A . n A 1 320 LYS 320 320 320 LYS ALA A . n A 1 321 HIS 321 321 321 HIS HIS A . n A 1 322 ALA 322 322 322 ALA ALA A . n A 1 323 THR 323 323 323 THR ALA A . n A 1 324 VAL 324 324 324 VAL VAL A . n A 1 325 ASP 325 325 325 ASP ASP A . n A 1 326 ILE 326 326 326 ILE ILE A . n A 1 327 CYS 327 327 327 CYS CYS A . n A 1 328 ALA 328 328 328 ALA ALA A . n A 1 329 TYR 329 329 329 TYR TYR A . n A 1 330 PRO 330 330 330 PRO PRO A . n A 1 331 GLU 331 331 331 GLU GLU A . n A 1 332 GLU 332 332 332 GLU GLU A . n A 1 333 SER 333 333 333 SER SER A . n A 1 334 LEU 334 334 334 LEU LEU A . n A 1 335 ASP 335 335 335 ASP ASP A . n A 1 336 TYR 336 336 336 TYR TYR A . n A 1 337 ARG 337 337 337 ARG ARG A . n A 1 338 TYR 338 338 338 TYR TYR A . n A 1 339 HIS 339 339 339 HIS HIS A . n A 1 340 LEU 340 340 340 LEU LEU A . n A 1 341 SER 341 341 341 SER SER A . n A 1 342 MET 342 342 342 MET MET A . n A 1 343 ALA 343 343 343 ALA ALA A . n A 1 344 HIS 344 344 344 HIS HIS A . n A 1 345 THR 345 345 345 THR THR A . n A 1 346 GLU 346 346 346 GLU GLU A . n A 1 347 ALA 347 347 347 ALA ALA A . n A 1 348 LEU 348 348 348 LEU LEU A . n A 1 349 ARG 349 349 349 ARG ARG A . n A 1 350 MET 350 350 350 MET MET A . n A 1 351 THR 351 351 351 THR THR A . n A 1 352 THR 352 352 352 THR THR A . n A 1 353 LYS 353 353 353 LYS LYS A . n A 1 354 ALA 354 354 354 ALA ALA A . n A 1 355 ASP 355 355 355 ASP ASP A . n A 1 356 GLN 356 356 356 GLN GLN A . n A 1 357 HIS 357 357 357 HIS ALA A . n A 1 358 ASP 358 358 358 ASP ASP A . n A 1 359 ILE 359 359 359 ILE ILE A . n A 1 360 ASN 360 360 360 ASN ASN A . n A 1 361 GLU 361 361 361 GLU GLU A . n A 1 362 GLU 362 362 362 GLU GLU A . n A 1 363 SER 363 363 363 SER SER A . n A 1 364 TYR 364 364 364 TYR TYR A . n A 1 365 TYR 365 365 365 TYR TYR A . n A 1 366 HIS 366 366 366 HIS HIS A . n A 1 367 ILE 367 367 367 ILE ILE A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 ALA 369 369 369 ALA ALA A . n A 1 370 ARG 370 370 370 ARG ARG A . n A 1 371 ILE 371 371 371 ILE ILE A . n A 1 372 ALA 372 372 372 ALA ALA A . n A 1 373 THR 373 373 373 THR THR A . n A 1 374 SER 374 374 374 SER SER A . n A 1 375 ILE 375 375 375 ILE ILE A . n A 1 376 PHE 376 376 376 PHE PHE A . n A 1 377 ALA 377 377 377 ALA ALA A . n A 1 378 LEU 378 378 378 LEU LEU A . n A 1 379 SER 379 379 379 SER SER A . n A 1 380 GLU 380 380 380 GLU GLU A . n A 1 381 MET 381 381 381 MET MET A . n A 1 382 GLY 382 382 382 GLY GLY A . n A 1 383 ARG 383 383 383 ARG ARG A . n A 1 384 THR 384 384 384 THR THR A . n A 1 385 THR 385 385 385 THR THR A . n A 1 386 GLU 386 386 386 GLU GLU A . n A 1 387 TYR 387 387 387 TYR TYR A . n A 1 388 PHE 388 388 388 PHE PHE A . n A 1 389 LEU 389 389 389 LEU LEU A . n A 1 390 LEU 390 390 390 LEU LEU A . n A 1 391 ASP 391 391 391 ASP ASP A . n A 1 392 GLU 392 392 392 GLU GLU A . n A 1 393 ILE 393 393 393 ILE ILE A . n A 1 394 VAL 394 394 394 VAL VAL A . n A 1 395 ASP 395 395 395 ASP ASP A . n A 1 396 VAL 396 396 396 VAL VAL A . n A 1 397 GLN 397 397 397 GLN GLN A . n A 1 398 TYR 398 398 398 TYR TYR A . n A 1 399 GLN 399 399 399 GLN GLN A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 LYS 401 401 401 LYS LYS A . n A 1 402 PHE 402 402 402 PHE PHE A . n A 1 403 LEU 403 403 403 LEU LEU A . n A 1 404 ASN 404 404 404 ASN ASN A . n A 1 405 TYR 405 405 405 TYR TYR A . n A 1 406 ILE 406 406 406 ILE ILE A . n A 1 407 LEU 407 407 407 LEU LEU A . n A 1 408 MET 408 408 408 MET MET A . n A 1 409 ARG 409 409 409 ARG ARG A . n A 1 410 ILE 410 410 410 ILE ILE A . n A 1 411 GLY 411 411 411 GLY GLY A . n A 1 412 ALA 412 412 412 ALA ALA A . n A 1 413 GLY 413 413 413 GLY GLY A . n A 1 414 ALA 414 414 414 ALA ALA A . n A 1 415 HIS 415 415 415 HIS HIS A . n A 1 416 PRO 416 416 416 PRO PRO A . n A 1 417 ASN 417 417 417 ASN ASN A . n A 1 418 THR 418 418 418 THR THR A . n A 1 419 ILE 419 419 419 ILE ILE A . n A 1 420 SER 420 420 420 SER SER A . n A 1 421 GLY 421 421 421 GLY GLY A . n A 1 422 THR 422 422 422 THR THR A . n A 1 423 SER 423 423 423 SER SER A . n A 1 424 ASP 424 424 424 ASP ASP A . n A 1 425 LEU 425 425 425 LEU LEU A . n A 1 426 ILE 426 426 426 ILE ILE A . n A 1 427 PHE 427 427 427 PHE PHE A . n A 1 428 ALA 428 428 428 ALA ALA A . n A 1 429 ASP 429 429 429 ASP ASP A . n A 1 430 PRO 430 430 430 PRO PRO A . n A 1 431 SER 431 431 431 SER SER A . n A 1 432 GLN 432 432 432 GLN GLN A . n A 1 433 LEU 433 433 433 LEU LEU A . n A 1 434 HIS 434 434 434 HIS HIS A . n A 1 435 ASP 435 435 435 ASP ASP A . n A 1 436 GLU 436 436 436 GLU GLU A . n A 1 437 LEU 437 437 437 LEU LEU A . n A 1 438 SER 438 438 438 SER SER A . n A 1 439 LEU 439 439 439 LEU LEU A . n A 1 440 LEU 440 440 440 LEU LEU A . n A 1 441 PHE 441 441 441 PHE PHE A . n A 1 442 GLY 442 442 442 GLY GLY A . n A 1 443 GLN 443 443 443 GLN ALA A . n A 1 444 VAL 444 444 ? ? ? A . n A 1 445 LYS 445 445 ? ? ? A . n A 1 446 PRO 446 446 ? ? ? A . n A 1 447 ALA 447 447 ? ? ? A . n A 1 448 ASN 448 448 ? ? ? A . n A 1 449 VAL 449 449 ? ? ? A . n A 1 450 ASP 450 450 ? ? ? A . n A 1 451 TYR 451 451 ? ? ? A . n A 1 452 PHE 452 452 452 PHE PHE A . n A 1 453 ILE 453 453 453 ILE ILE A . n A 1 454 SER 454 454 454 SER SER A . n A 1 455 TYR 455 455 455 TYR TYR A . n A 1 456 ASP 456 456 456 ASP ASP A . n A 1 457 GLU 457 457 457 GLU GLU A . n A 1 458 ALA 458 458 458 ALA ALA A . n A 1 459 ARG 459 459 459 ARG ARG A . n A 1 460 ASP 460 460 460 ASP ASP A . n A 1 461 GLN 461 461 461 GLN GLN A . n A 1 462 LEU 462 462 462 LEU LEU A . n A 1 463 LYS 463 463 463 LYS LYS A . n A 1 464 THR 464 464 464 THR THR A . n A 1 465 ALA 465 465 465 ALA ALA A . n A 1 466 TYR 466 466 466 TYR TYR A . n A 1 467 ALA 467 467 467 ALA ALA A . n A 1 468 LEU 468 468 468 LEU LEU A . n A 1 469 SER 469 469 469 SER SER A . n A 1 470 ARG 470 470 470 ARG ARG A . n A 1 471 GLY 471 471 471 GLY GLY A . n A 1 472 GLN 472 472 472 GLN GLN A . n A 1 473 ASP 473 473 473 ASP ASP A . n A 1 474 HIS 474 474 474 HIS HIS A . n A 1 475 VAL 475 475 475 VAL VAL A . n A 1 476 ASN 476 476 476 ASN ASN A . n A 1 477 ALA 477 477 477 ALA ALA A . n A 1 478 LEU 478 478 478 LEU LEU A . n A 1 479 SER 479 479 479 SER SER A . n A 1 480 LEU 480 480 480 LEU LEU A . n A 1 481 ALA 481 481 481 ALA ALA A . n A 1 482 ARG 482 482 482 ARG ARG A . n A 1 483 ARG 483 483 483 ARG ARG A . n A 1 484 VAL 484 484 484 VAL VAL A . n A 1 485 ILE 485 485 485 ILE ILE A . n A 1 486 MET 486 486 486 MET MET A . n A 1 487 SER 487 487 487 SER SER A . n A 1 488 ILE 488 488 488 ILE ILE A . n A 1 489 TYR 489 489 489 TYR TYR A . n A 1 490 LYS 490 490 490 LYS LYS A . n A 1 491 GLY 491 491 491 GLY GLY A . n A 1 492 LEU 492 492 492 LEU LEU A . n A 1 493 LEU 493 493 493 LEU LEU A . n A 1 494 VAL 494 494 494 VAL VAL A . n A 1 495 LYS 495 495 495 LYS LYS A . n A 1 496 GLN 496 496 496 GLN GLN A . n A 1 497 ASN 497 497 497 ASN ASN A . n A 1 498 LEU 498 498 498 LEU LEU A . n A 1 499 ASN 499 499 499 ASN ASN A . n A 1 500 ALA 500 500 500 ALA ALA A . n A 1 501 THR 501 501 501 THR THR A . n A 1 502 GLU 502 502 502 GLU GLU A . n A 1 503 ARG 503 503 503 ARG ARG A . n A 1 504 GLN 504 504 504 GLN GLN A . n A 1 505 ALA 505 505 505 ALA ALA A . n A 1 506 LEU 506 506 506 LEU LEU A . n A 1 507 PHE 507 507 507 PHE PHE A . n A 1 508 PHE 508 508 508 PHE PHE A . n A 1 509 ALA 509 509 509 ALA ALA A . n A 1 510 SER 510 510 510 SER SER A . n A 1 511 MET 511 511 511 MET MET A . n A 1 512 ILE 512 512 512 ILE ILE A . n A 1 513 LEU 513 513 513 LEU LEU A . n A 1 514 LEU 514 514 514 LEU LEU A . n A 1 515 ASN 515 515 515 ASN ASN A . n A 1 516 PHE 516 516 516 PHE PHE A . n A 1 517 ARG 517 517 ? ? ? A . n A 1 518 GLU 518 518 ? ? ? A . n A 1 519 GLY 519 519 ? ? ? A . n A 1 520 LEU 520 520 ? ? ? A . n A 1 521 GLU 521 521 ? ? ? A . n A 1 522 ASN 522 522 ? ? ? A . n A 1 523 SER 523 523 523 SER SER A . n A 1 524 SER 524 524 524 SER SER A . n A 1 525 ARG 525 525 525 ARG ALA A . n A 1 526 VAL 526 526 526 VAL VAL A . n A 1 527 LEU 527 527 527 LEU LEU A . n A 1 528 ASP 528 528 528 ASP ASP A . n A 1 529 GLY 529 529 529 GLY GLY A . n A 1 530 ARG 530 530 530 ARG ARG A . n A 1 531 THR 531 531 531 THR THR A . n A 1 532 THR 532 532 532 THR THR A . n A 1 533 LEU 533 533 533 LEU LEU A . n A 1 534 LEU 534 534 534 LEU LEU A . n A 1 535 LEU 535 535 535 LEU LEU A . n A 1 536 MET 536 536 536 MET MET A . n A 1 537 THR 537 537 537 THR THR A . n A 1 538 SER 538 538 538 SER SER A . n A 1 539 MET 539 539 539 MET MET A . n A 1 540 CYS 540 540 540 CYS CYS A . n A 1 541 THR 541 541 541 THR THR A . n A 1 542 ALA 542 542 542 ALA ALA A . n A 1 543 ALA 543 543 543 ALA ALA A . n A 1 544 HIS 544 544 544 HIS HIS A . n A 1 545 ALA 545 545 545 ALA ALA A . n A 1 546 THR 546 546 546 THR THR A . n A 1 547 GLN 547 547 547 GLN GLN A . n A 1 548 ALA 548 548 548 ALA ALA A . n A 1 549 ALA 549 549 549 ALA ALA A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 ASN 551 551 551 ASN ASN A . n A 1 552 ILE 552 552 552 ILE ILE A . n A 1 553 GLN 553 553 553 GLN GLN A . n A 1 554 GLU 554 554 554 GLU GLU A . n A 1 555 GLY 555 555 555 GLY GLY A . n A 1 556 LEU 556 556 556 LEU LEU A . n A 1 557 ALA 557 557 557 ALA ALA A . n A 1 558 TYR 558 558 558 TYR TYR A . n A 1 559 LEU 559 559 559 LEU LEU A . n A 1 560 ASN 560 560 560 ASN ASN A . n A 1 561 PRO 561 561 561 PRO PRO A . n A 1 562 SER 562 562 562 SER SER A . n A 1 563 LYS 563 563 563 LYS LYS A . n A 1 564 HIS 564 564 564 HIS HIS A . n A 1 565 MET 565 565 565 MET MET A . n A 1 566 PHE 566 566 566 PHE PHE A . n A 1 567 THR 567 567 567 THR THR A . n A 1 568 ILE 568 568 568 ILE ILE A . n A 1 569 PRO 569 569 569 PRO PRO A . n A 1 570 ASN 570 570 570 ASN ASN A . n A 1 571 VAL 571 571 571 VAL VAL A . n A 1 572 TYR 572 572 572 TYR TYR A . n A 1 573 SER 573 573 573 SER SER A . n A 1 574 PRO 574 574 574 PRO PRO A . n A 1 575 CYS 575 575 575 CYS CYS A . n A 1 576 MET 576 576 576 MET MET A . n A 1 577 GLY 577 577 577 GLY GLY A . n A 1 578 SER 578 578 578 SER SER A . n A 1 579 LEU 579 579 579 LEU LEU A . n A 1 580 ARG 580 580 580 ARG ARG A . n A 1 581 THR 581 581 581 THR THR A . n A 1 582 ASP 582 582 582 ASP ASP A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 THR 584 584 584 THR THR A . n A 1 585 GLU 585 585 585 GLU GLU A . n A 1 586 GLU 586 586 586 GLU GLU A . n A 1 587 ILE 587 587 587 ILE ILE A . n A 1 588 HIS 588 588 588 HIS HIS A . n A 1 589 VAL 589 589 589 VAL VAL A . n A 1 590 MET 590 590 590 MET MET A . n A 1 591 ASN 591 591 591 ASN ASN A . n A 1 592 LEU 592 592 592 LEU LEU A . n A 1 593 LEU 593 593 593 LEU LEU A . n A 1 594 SER 594 594 594 SER SER A . n A 1 595 ALA 595 595 595 ALA ALA A . n A 1 596 ILE 596 596 596 ILE ILE A . n A 1 597 PRO 597 597 597 PRO PRO A . n A 1 598 THR 598 598 598 THR THR A . n A 1 599 ARG 599 599 599 ARG ARG A . n A 1 600 PRO 600 600 600 PRO PRO A . n A 1 601 GLY 601 601 601 GLY GLY A . n A 1 602 LEU 602 602 602 LEU LEU A . n A 1 603 ASN 603 603 603 ASN ASN A . n A 1 604 GLU 604 604 604 GLU GLU A . n A 1 605 VAL 605 605 605 VAL VAL A . n A 1 606 LEU 606 606 606 LEU LEU A . n A 1 607 HIS 607 607 607 HIS HIS A . n A 1 608 THR 608 608 608 THR THR A . n A 1 609 GLN 609 609 609 GLN GLN A . n A 1 610 LEU 610 610 610 LEU LEU A . n A 1 611 ASP 611 611 611 ASP ASP A . n A 1 612 GLU 612 612 612 GLU ALA A . n A 1 613 SER 613 613 613 SER SER A . n A 1 614 GLU 614 614 614 GLU GLU A . n A 1 615 ILE 615 615 615 ILE ILE A . n A 1 616 PHE 616 616 616 PHE PHE A . n A 1 617 ASP 617 617 617 ASP ASP A . n A 1 618 ALA 618 618 618 ALA ALA A . n A 1 619 ALA 619 619 619 ALA ALA A . n A 1 620 PHE 620 620 620 PHE PHE A . n A 1 621 LYS 621 621 621 LYS LYS A . n A 1 622 THR 622 622 622 THR THR A . n A 1 623 MET 623 623 623 MET MET A . n A 1 624 MET 624 624 624 MET MET A . n A 1 625 ILE 625 625 625 ILE ILE A . n A 1 626 PHE 626 626 626 PHE PHE A . n A 1 627 THR 627 627 627 THR THR A . n A 1 628 THR 628 628 628 THR THR A . n A 1 629 TRP 629 629 629 TRP TRP A . n A 1 630 THR 630 630 630 THR THR A . n A 1 631 ALA 631 631 631 ALA ALA A . n A 1 632 LYS 632 632 632 LYS LYS A . n A 1 633 ASP 633 633 633 ASP ASP A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 HIS 635 635 635 HIS HIS A . n A 1 636 ILE 636 636 636 ILE ILE A . n A 1 637 LEU 637 637 637 LEU LEU A . n A 1 638 HIS 638 638 638 HIS HIS A . n A 1 639 THR 639 639 639 THR THR A . n A 1 640 HIS 640 640 640 HIS HIS A . n A 1 641 VAL 641 641 641 VAL VAL A . n A 1 642 PRO 642 642 642 PRO PRO A . n A 1 643 GLU 643 643 643 GLU GLU A . n A 1 644 VAL 644 644 644 VAL VAL A . n A 1 645 PHE 645 645 645 PHE PHE A . n A 1 646 THR 646 646 646 THR THR A . n A 1 647 CYS 647 647 647 CYS CYS A . n A 1 648 GLN 648 648 648 GLN ALA A . n A 1 649 ASP 649 649 649 ASP ASP A . n A 1 650 ALA 650 650 650 ALA ALA A . n A 1 651 ALA 651 651 651 ALA ALA A . n A 1 652 ALA 652 652 652 ALA ALA A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 ASN 654 654 654 ASN ASN A . n A 1 655 GLY 655 655 655 GLY GLY A . n A 1 656 GLU 656 656 656 GLU GLU A . n A 1 657 TYR 657 657 657 TYR TYR A . n A 1 658 VAL 658 658 658 VAL VAL A . n A 1 659 LEU 659 659 659 LEU LEU A . n A 1 660 ILE 660 660 660 ILE ILE A . n A 1 661 LEU 661 661 661 LEU LEU A . n A 1 662 PRO 662 662 662 PRO PRO A . n A 1 663 ALA 663 663 663 ALA ALA A . n A 1 664 VAL 664 664 664 VAL VAL A . n A 1 665 GLN 665 665 665 GLN GLN A . n A 1 666 GLY 666 666 666 GLY GLY A . n A 1 667 HIS 667 667 667 HIS HIS A . n A 1 668 SER 668 668 668 SER SER A . n A 1 669 TYR 669 669 669 TYR TYR A . n A 1 670 VAL 670 670 670 VAL VAL A . n A 1 671 ILE 671 671 671 ILE ILE A . n A 1 672 THR 672 672 672 THR THR A . n A 1 673 ARG 673 673 673 ARG ARG A . n A 1 674 ASN 674 674 674 ASN ASN A . n A 1 675 LYS 675 675 675 LYS LYS A . n A 1 676 PRO 676 676 676 PRO PRO A . n A 1 677 GLN 677 677 677 GLN GLN A . n A 1 678 ARG 678 678 678 ARG ARG A . n A 1 679 GLY 679 679 679 GLY GLY A . n A 1 680 LEU 680 680 680 LEU LEU A . n A 1 681 VAL 681 681 681 VAL VAL A . n A 1 682 TYR 682 682 682 TYR TYR A . n A 1 683 SER 683 683 683 SER SER A . n A 1 684 LEU 684 684 684 LEU LEU A . n A 1 685 ALA 685 685 685 ALA ALA A . n A 1 686 ASP 686 686 686 ASP ASP A . n A 1 687 VAL 687 687 687 VAL VAL A . n A 1 688 ASP 688 688 688 ASP ASP A . n A 1 689 VAL 689 689 689 VAL VAL A . n A 1 690 TYR 690 690 690 TYR TYR A . n A 1 691 ASN 691 691 691 ASN ASN A . n A 1 692 PRO 692 692 692 PRO PRO A . n A 1 693 ILE 693 693 693 ILE ILE A . n A 1 694 SER 694 694 694 SER SER A . n A 1 695 VAL 695 695 695 VAL VAL A . n A 1 696 VAL 696 696 696 VAL VAL A . n A 1 697 TYR 697 697 697 TYR TYR A . n A 1 698 LEU 698 698 698 LEU LEU A . n A 1 699 SER 699 699 699 SER SER A . n A 1 700 LYS 700 700 700 LYS LYS A . n A 1 701 ASP 701 701 701 ASP ASP A . n A 1 702 THR 702 702 702 THR THR A . n A 1 703 CYS 703 703 703 CYS CYS A . n A 1 704 VAL 704 704 704 VAL VAL A . n A 1 705 SER 705 705 705 SER SER A . n A 1 706 GLU 706 706 706 GLU GLU A . n A 1 707 HIS 707 707 707 HIS HIS A . n A 1 708 GLY 708 708 708 GLY GLY A . n A 1 709 VAL 709 709 709 VAL VAL A . n A 1 710 ILE 710 710 710 ILE ILE A . n A 1 711 GLU 711 711 711 GLU GLU A . n A 1 712 THR 712 712 712 THR THR A . n A 1 713 VAL 713 713 713 VAL VAL A . n A 1 714 ALA 714 714 714 ALA ALA A . n A 1 715 LEU 715 715 715 LEU LEU A . n A 1 716 PRO 716 716 716 PRO PRO A . n A 1 717 HIS 717 717 717 HIS HIS A . n A 1 718 PRO 718 718 718 PRO PRO A . n A 1 719 ASP 719 719 719 ASP ASP A . n A 1 720 ASN 720 720 720 ASN ASN A . n A 1 721 LEU 721 721 721 LEU LEU A . n A 1 722 LYS 722 722 722 LYS LYS A . n A 1 723 GLU 723 723 723 GLU GLU A . n A 1 724 CYS 724 724 724 CYS CYS A . n A 1 725 LEU 725 725 725 LEU LEU A . n A 1 726 TYR 726 726 726 TYR TYR A . n A 1 727 CYS 727 727 727 CYS CYS A . n A 1 728 GLY 728 728 728 GLY GLY A . n A 1 729 SER 729 729 729 SER SER A . n A 1 730 VAL 730 730 730 VAL VAL A . n A 1 731 PHE 731 731 731 PHE PHE A . n A 1 732 LEU 732 732 732 LEU LEU A . n A 1 733 ARG 733 733 733 ARG ARG A . n A 1 734 TYR 734 734 734 TYR TYR A . n A 1 735 LEU 735 735 735 LEU LEU A . n A 1 736 THR 736 736 736 THR THR A . n A 1 737 THR 737 737 737 THR THR A . n A 1 738 GLY 738 738 738 GLY GLY A . n A 1 739 ALA 739 739 739 ALA ALA A . n A 1 740 ILE 740 740 740 ILE ILE A . n A 1 741 MET 741 741 741 MET MET A . n A 1 742 ASP 742 742 742 ASP ASP A . n A 1 743 ILE 743 743 743 ILE ILE A . n A 1 744 ILE 744 744 744 ILE ILE A . n A 1 745 ILE 745 745 745 ILE ILE A . n A 1 746 ILE 746 746 746 ILE ILE A . n A 1 747 ASP 747 747 747 ASP ASP A . n A 1 748 SER 748 748 748 SER SER A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 ASP 750 750 750 ASP ASP A . n A 1 751 THR 751 751 751 THR THR A . n A 1 752 GLU 752 752 752 GLU GLU A . n A 1 753 ARG 753 753 753 ARG ARG A . n A 1 754 GLN 754 754 754 GLN GLN A . n A 1 755 LEU 755 755 755 LEU LEU A . n A 1 756 ALA 756 756 756 ALA ALA A . n A 1 757 ALA 757 757 757 ALA ALA A . n A 1 758 MET 758 758 758 MET ALA A . n A 1 759 GLY 759 759 759 GLY GLY A . n A 1 760 ASN 760 760 760 ASN ASN A . n A 1 761 SER 761 761 761 SER SER A . n A 1 762 THR 762 762 762 THR THR A . n A 1 763 ILE 763 763 763 ILE ILE A . n A 1 764 PRO 764 764 764 PRO PRO A . n A 1 765 PRO 765 765 765 PRO PRO A . n A 1 766 PHE 766 766 766 PHE PHE A . n A 1 767 ASN 767 767 767 ASN ASN A . n A 1 768 PRO 768 768 768 PRO PRO A . n A 1 769 ASP 769 769 769 ASP ASP A . n A 1 770 MET 770 770 770 MET MET A . n A 1 771 HIS 771 771 771 HIS HIS A . n A 1 772 GLY 772 772 772 GLY GLY A . n A 1 773 ASP 773 773 773 ASP ASP A . n A 1 774 ASP 774 774 774 ASP ASP A . n A 1 775 SER 775 775 775 SER SER A . n A 1 776 LYS 776 776 776 LYS LYS A . n A 1 777 ALA 777 777 777 ALA ALA A . n A 1 778 VAL 778 778 778 VAL VAL A . n A 1 779 LEU 779 779 779 LEU LEU A . n A 1 780 LEU 780 780 780 LEU LEU A . n A 1 781 PHE 781 781 781 PHE PHE A . n A 1 782 PRO 782 782 782 PRO PRO A . n A 1 783 ASN 783 783 783 ASN ASN A . n A 1 784 GLY 784 784 784 GLY GLY A . n A 1 785 THR 785 785 785 THR THR A . n A 1 786 VAL 786 786 786 VAL VAL A . n A 1 787 VAL 787 787 787 VAL VAL A . n A 1 788 THR 788 788 788 THR THR A . n A 1 789 LEU 789 789 789 LEU LEU A . n A 1 790 LEU 790 790 790 LEU LEU A . n A 1 791 GLY 791 791 791 GLY GLY A . n A 1 792 PHE 792 792 ? ? ? A . n A 1 793 GLU 793 793 ? ? ? A . n A 1 794 ARG 794 794 ? ? ? A . n A 1 795 ARG 795 795 ? ? ? A . n A 1 796 GLY 796 796 ? ? ? A . n A 1 797 SER 797 797 ? ? ? A . n A 1 798 GLU 798 798 ? ? ? A . n A 1 799 ASN 799 799 ? ? ? A . n A 1 800 LEU 800 800 ? ? ? A . n A 1 801 TYR 801 801 ? ? ? A . n A 1 802 PHE 802 802 ? ? ? A . n A 1 803 GLN 803 803 ? ? ? A . n A 1 804 GLY 804 804 ? ? ? A . n A 1 805 SER 805 805 ? ? ? A . n A 1 806 TRP 806 806 ? ? ? A . n A 1 807 SER 807 807 ? ? ? A . n A 1 808 HIS 808 808 ? ? ? A . n A 1 809 PRO 809 809 ? ? ? A . n A 1 810 GLN 810 810 ? ? ? A . n A 1 811 PHE 811 811 ? ? ? A . n A 1 812 GLU 812 812 ? ? ? A . n A 1 813 LYS 813 813 ? ? ? A . n A 1 814 GLY 814 814 ? ? ? A . n A 1 815 GLY 815 815 ? ? ? A . n A 1 816 GLY 816 816 ? ? ? A . n A 1 817 SER 817 817 ? ? ? A . n A 1 818 GLY 818 818 ? ? ? A . n A 1 819 GLY 819 819 ? ? ? A . n A 1 820 GLY 820 820 ? ? ? A . n A 1 821 SER 821 821 ? ? ? A . n A 1 822 GLY 822 822 ? ? ? A . n A 1 823 GLY 823 823 ? ? ? A . n A 1 824 GLY 824 824 ? ? ? A . n A 1 825 SER 825 825 ? ? ? A . n A 1 826 TRP 826 826 ? ? ? A . n A 1 827 SER 827 827 ? ? ? A . n A 1 828 HIS 828 828 ? ? ? A . n A 1 829 PRO 829 829 ? ? ? A . n A 1 830 GLN 830 830 ? ? ? A . n A 1 831 PHE 831 831 ? ? ? A . n A 1 832 GLU 832 832 ? ? ? A . n A 1 833 LYS 833 833 ? ? ? A . n B 2 1 LEU 1 23 ? ? ? B . n B 2 2 HIS 2 24 ? ? ? B . n B 2 3 LEU 3 25 ? ? ? B . n B 2 4 GLN 4 26 ? ? ? B . n B 2 5 ASP 5 27 ? ? ? B . n B 2 6 ASP 6 28 ? ? ? B . n B 2 7 THR 7 29 29 THR ALA B . n B 2 8 PRO 8 30 30 PRO ALA B . n B 2 9 LEU 9 31 31 LEU ALA B . n B 2 10 PHE 10 32 32 PHE PHE B . n B 2 11 PHE 11 33 33 PHE PHE B . n B 2 12 GLY 12 34 34 GLY GLY B . n B 2 13 ALA 13 35 35 ALA ALA B . n B 2 14 LYS 14 36 36 LYS LYS B . n B 2 15 PRO 15 37 37 PRO PRO B . n B 2 16 LEU 16 38 38 LEU LEU B . n B 2 17 SER 17 39 39 SER SER B . n B 2 18 ASP 18 40 40 ASP ASP B . n B 2 19 VAL 19 41 41 VAL VAL B . n B 2 20 SER 20 42 42 SER SER B . n B 2 21 LEU 21 43 43 LEU LEU B . n B 2 22 ILE 22 44 44 ILE ILE B . n B 2 23 ILE 23 45 45 ILE ILE B . n B 2 24 THR 24 46 46 THR THR B . n B 2 25 GLU 25 47 47 GLU GLU B . n B 2 26 PRO 26 48 48 PRO PRO B . n B 2 27 CYS 27 49 49 CYS CYS B . n B 2 28 VAL 28 50 50 VAL VAL B . n B 2 29 SER 29 51 51 SER SER B . n B 2 30 SER 30 52 52 SER SER B . n B 2 31 VAL 31 53 53 VAL VAL B . n B 2 32 TYR 32 54 54 TYR TYR B . n B 2 33 GLU 33 55 55 GLU ALA B . n B 2 34 ALA 34 56 56 ALA ALA B . n B 2 35 TRP 35 57 57 TRP TRP B . n B 2 36 ASP 36 58 58 ASP ASP B . n B 2 37 TYR 37 59 59 TYR TYR B . n B 2 38 ALA 38 60 60 ALA ALA B . n B 2 39 ALA 39 61 61 ALA ALA B . n B 2 40 PRO 40 62 62 PRO PRO B . n B 2 41 PRO 41 63 63 PRO PRO B . n B 2 42 VAL 42 64 64 VAL VAL B . n B 2 43 SER 43 65 65 SER SER B . n B 2 44 ASN 44 66 66 ASN ASN B . n B 2 45 LEU 45 67 67 LEU LEU B . n B 2 46 SER 46 68 68 SER SER B . n B 2 47 GLU 47 69 69 GLU GLU B . n B 2 48 ALA 48 70 70 ALA ALA B . n B 2 49 LEU 49 71 71 LEU LEU B . n B 2 50 SER 50 72 72 SER SER B . n B 2 51 GLY 51 73 73 GLY GLY B . n B 2 52 ILE 52 74 74 ILE ILE B . n B 2 53 VAL 53 75 75 VAL VAL B . n B 2 54 VAL 54 76 76 VAL VAL B . n B 2 55 LYS 55 77 77 LYS LYS B . n B 2 56 THR 56 78 78 THR THR B . n B 2 57 LYS 57 79 79 LYS LYS B . n B 2 58 CYS 58 80 80 CYS CYS B . n B 2 59 PRO 59 81 81 PRO PRO B . n B 2 60 VAL 60 82 82 VAL VAL B . n B 2 61 PRO 61 83 83 PRO PRO B . n B 2 62 GLU 62 84 84 GLU GLU B . n B 2 63 VAL 63 85 85 VAL VAL B . n B 2 64 ILE 64 86 86 ILE ILE B . n B 2 65 LEU 65 87 87 LEU LEU B . n B 2 66 TRP 66 88 88 TRP TRP B . n B 2 67 PHE 67 89 89 PHE PHE B . n B 2 68 LYS 68 90 90 LYS LYS B . n B 2 69 ASP 69 91 91 ASP ASP B . n B 2 70 LYS 70 92 92 LYS LYS B . n B 2 71 GLN 71 93 93 GLN GLN B . n B 2 72 MET 72 94 94 MET MET B . n B 2 73 ALA 73 95 95 ALA ALA B . n B 2 74 TYR 74 96 96 TYR TYR B . n B 2 75 TRP 75 97 97 TRP TRP B . n B 2 76 THR 76 98 98 THR THR B . n B 2 77 ASN 77 99 99 ASN ASN B . n B 2 78 PRO 78 100 100 PRO PRO B . n B 2 79 TYR 79 101 101 TYR TYR B . n B 2 80 VAL 80 102 102 VAL VAL B . n B 2 81 THR 81 103 103 THR THR B . n B 2 82 LEU 82 104 104 LEU LEU B . n B 2 83 LYS 83 105 105 LYS LYS B . n B 2 84 GLY 84 106 106 GLY GLY B . n B 2 85 LEU 85 107 107 LEU LEU B . n B 2 86 THR 86 108 108 THR THR B . n B 2 87 GLN 87 109 109 GLN GLN B . n B 2 88 SER 88 110 110 SER SER B . n B 2 89 VAL 89 111 111 VAL VAL B . n B 2 90 GLY 90 112 112 GLY GLY B . n B 2 91 GLU 91 113 113 GLU GLU B . n B 2 92 GLU 92 114 114 GLU GLU B . n B 2 93 HIS 93 115 115 HIS HIS B . n B 2 94 LYS 94 116 116 LYS LYS B . n B 2 95 SER 95 117 117 SER SER B . n B 2 96 GLY 96 118 118 GLY GLY B . n B 2 97 ASP 97 119 119 ASP ASP B . n B 2 98 ILE 98 120 120 ILE ILE B . n B 2 99 ARG 99 121 121 ARG ARG B . n B 2 100 ASP 100 122 122 ASP ASP B . n B 2 101 ALA 101 123 123 ALA ALA B . n B 2 102 LEU 102 124 124 LEU LEU B . n B 2 103 LEU 103 125 125 LEU LEU B . n B 2 104 ASP 104 126 126 ASP ASP B . n B 2 105 ALA 105 127 127 ALA ALA B . n B 2 106 LEU 106 128 128 LEU LEU B . n B 2 107 SER 107 129 129 SER SER B . n B 2 108 GLY 108 130 130 GLY GLY B . n B 2 109 VAL 109 131 131 VAL VAL B . n B 2 110 TRP 110 132 132 TRP TRP B . n B 2 111 VAL 111 133 133 VAL VAL B . n B 2 112 ASP 112 134 134 ASP ASP B . n B 2 113 SER 113 135 135 SER SER B . n B 2 114 THR 114 136 136 THR THR B . n B 2 115 PRO 115 137 137 PRO PRO B . n B 2 116 SER 116 138 138 SER SER B . n B 2 117 SER 117 139 139 SER SER B . n B 2 118 THR 118 140 140 THR THR B . n B 2 119 ASN 119 141 141 ASN ASN B . n B 2 120 ILE 120 142 142 ILE ILE B . n B 2 121 PRO 121 143 143 PRO PRO B . n B 2 122 GLU 122 144 144 GLU GLU B . n B 2 123 ASN 123 145 145 ASN ASN B . n B 2 124 GLY 124 146 146 GLY GLY B . n B 2 125 CYS 125 147 147 CYS CYS B . n B 2 126 VAL 126 148 148 VAL VAL B . n B 2 127 TRP 127 149 149 TRP TRP B . n B 2 128 GLY 128 150 150 GLY GLY B . n B 2 129 ALA 129 151 151 ALA ALA B . n B 2 130 ASP 130 152 152 ASP ASP B . n B 2 131 ARG 131 153 153 ARG ARG B . n B 2 132 LEU 132 154 154 LEU LEU B . n B 2 133 PHE 133 155 155 PHE PHE B . n B 2 134 GLN 134 156 156 GLN GLN B . n B 2 135 ARG 135 157 157 ARG ARG B . n B 2 136 VAL 136 158 158 VAL VAL B . n B 2 137 CYS 137 159 159 CYS CYS B . n B 2 138 GLN 138 160 160 GLN GLN B . n C 3 1 ASP 1 1 1 ASP ASP C . n C 3 2 ILE 2 2 2 ILE ILE C . n C 3 3 GLN 3 3 3 GLN GLN C . n C 3 4 MET 4 4 4 MET MET C . n C 3 5 THR 5 5 5 THR THR C . n C 3 6 GLN 6 6 6 GLN GLN C . n C 3 7 SER 7 7 7 SER SER C . n C 3 8 PRO 8 8 8 PRO PRO C . n C 3 9 SER 9 9 9 SER SER C . n C 3 10 SER 10 10 10 SER SER C . n C 3 11 VAL 11 11 11 VAL VAL C . n C 3 12 SER 12 12 12 SER SER C . n C 3 13 ALA 13 13 13 ALA ALA C . n C 3 14 SER 14 14 14 SER SER C . n C 3 15 VAL 15 15 15 VAL VAL C . n C 3 16 GLY 16 16 16 GLY GLY C . n C 3 17 ASP 17 17 17 ASP ASP C . n C 3 18 ARG 18 18 18 ARG ARG C . n C 3 19 VAL 19 19 19 VAL VAL C . n C 3 20 THR 20 20 20 THR THR C . n C 3 21 ILE 21 21 21 ILE ILE C . n C 3 22 THR 22 22 22 THR THR C . n C 3 23 CYS 23 23 23 CYS CYS C . n C 3 24 ARG 24 24 24 ARG ARG C . n C 3 25 ALA 25 25 25 ALA ALA C . n C 3 26 SER 26 26 26 SER SER C . n C 3 27 GLN 27 27 27 GLN GLN C . n C 3 28 GLY 28 28 28 GLY GLY C . n C 3 29 ILE 29 29 29 ILE ILE C . n C 3 30 SER 30 30 30 SER ALA C . n C 3 31 SER 31 31 31 SER ALA C . n C 3 32 TRP 32 32 32 TRP TRP C . n C 3 33 LEU 33 33 33 LEU LEU C . n C 3 34 ALA 34 34 34 ALA ALA C . n C 3 35 TRP 35 35 35 TRP TRP C . n C 3 36 TYR 36 36 36 TYR TYR C . n C 3 37 GLN 37 37 37 GLN ALA C . n C 3 38 GLN 38 38 38 GLN GLN C . n C 3 39 LYS 39 39 39 LYS LYS C . n C 3 40 PRO 40 40 40 PRO PRO C . n C 3 41 GLY 41 41 41 GLY GLY C . n C 3 42 LYS 42 42 42 LYS ALA C . n C 3 43 ALA 43 43 43 ALA ALA C . n C 3 44 PRO 44 44 44 PRO PRO C . n C 3 45 LYS 45 45 45 LYS LYS C . n C 3 46 LEU 46 46 46 LEU LEU C . n C 3 47 LEU 47 47 47 LEU LEU C . n C 3 48 ILE 48 48 48 ILE ILE C . n C 3 49 TYR 49 49 49 TYR TYR C . n C 3 50 ALA 50 50 50 ALA ALA C . n C 3 51 ALA 51 51 51 ALA ALA C . n C 3 52 SER 52 52 52 SER SER C . n C 3 53 SER 53 53 53 SER SER C . n C 3 54 LEU 54 54 54 LEU LEU C . n C 3 55 GLN 55 55 55 GLN GLN C . n C 3 56 SER 56 56 56 SER SER C . n C 3 57 GLY 57 57 57 GLY GLY C . n C 3 58 VAL 58 58 58 VAL VAL C . n C 3 59 PRO 59 59 59 PRO PRO C . n C 3 60 SER 60 60 60 SER SER C . n C 3 61 ARG 61 61 61 ARG ARG C . n C 3 62 PHE 62 62 62 PHE PHE C . n C 3 63 SER 63 63 63 SER SER C . n C 3 64 GLY 64 64 64 GLY GLY C . n C 3 65 SER 65 65 65 SER SER C . n C 3 66 GLY 66 66 66 GLY GLY C . n C 3 67 SER 67 67 67 SER SER C . n C 3 68 GLY 68 68 68 GLY GLY C . n C 3 69 THR 69 69 69 THR THR C . n C 3 70 ASP 70 70 70 ASP ASP C . n C 3 71 PHE 71 71 71 PHE PHE C . n C 3 72 THR 72 72 72 THR THR C . n C 3 73 LEU 73 73 73 LEU LEU C . n C 3 74 THR 74 74 74 THR THR C . n C 3 75 ILE 75 75 75 ILE ILE C . n C 3 76 SER 76 76 76 SER SER C . n C 3 77 SER 77 77 77 SER SER C . n C 3 78 LEU 78 78 78 LEU LEU C . n C 3 79 GLN 79 79 79 GLN GLN C . n C 3 80 PRO 80 80 80 PRO PRO C . n C 3 81 GLU 81 81 81 GLU GLU C . n C 3 82 ASP 82 82 82 ASP ASP C . n C 3 83 PHE 83 83 83 PHE PHE C . n C 3 84 ALA 84 84 84 ALA ALA C . n C 3 85 THR 85 85 85 THR THR C . n C 3 86 TYR 86 86 86 TYR TYR C . n C 3 87 TYR 87 87 87 TYR TYR C . n C 3 88 CYS 88 88 88 CYS CYS C . n C 3 89 GLN 89 89 89 GLN GLN C . n C 3 90 GLN 90 90 90 GLN ALA C . n C 3 91 ALA 91 91 91 ALA ALA C . n C 3 92 ASN 92 92 92 ASN ASN C . n C 3 93 ASN 93 93 93 ASN ALA C . n C 3 94 PHE 94 94 94 PHE PHE C . n C 3 95 PRO 95 95 95 PRO PRO C . n C 3 96 LEU 96 96 96 LEU LEU C . n C 3 97 THR 97 97 97 THR THR C . n C 3 98 PHE 98 98 98 PHE PHE C . n C 3 99 GLY 99 99 99 GLY GLY C . n C 3 100 GLY 100 100 100 GLY GLY C . n C 3 101 GLY 101 101 101 GLY GLY C . n C 3 102 THR 102 102 102 THR THR C . n C 3 103 LYS 103 103 103 LYS LYS C . n C 3 104 VAL 104 104 104 VAL VAL C . n C 3 105 GLU 105 105 105 GLU GLU C . n C 3 106 ILE 106 106 106 ILE ILE C . n C 3 107 LYS 107 107 107 LYS LYS C . n C 3 108 ARG 108 108 108 ARG ARG C . n C 3 109 THR 109 109 109 THR THR C . n C 3 110 VAL 110 110 110 VAL VAL C . n C 3 111 ALA 111 111 111 ALA ALA C . n C 3 112 ALA 112 112 112 ALA ALA C . n C 3 113 PRO 113 113 113 PRO PRO C . n C 3 114 SER 114 114 114 SER SER C . n C 3 115 VAL 115 115 115 VAL VAL C . n C 3 116 PHE 116 116 116 PHE PHE C . n C 3 117 ILE 117 117 117 ILE ILE C . n C 3 118 PHE 118 118 118 PHE PHE C . n C 3 119 PRO 119 119 119 PRO PRO C . n C 3 120 PRO 120 120 120 PRO PRO C . n C 3 121 SER 121 121 121 SER SER C . n C 3 122 ASP 122 122 122 ASP ASP C . n C 3 123 GLU 123 123 123 GLU GLU C . n C 3 124 GLN 124 124 124 GLN GLN C . n C 3 125 LEU 125 125 125 LEU LEU C . n C 3 126 LYS 126 126 126 LYS LYS C . n C 3 127 SER 127 127 127 SER SER C . n C 3 128 GLY 128 128 128 GLY GLY C . n C 3 129 THR 129 129 129 THR THR C . n C 3 130 ALA 130 130 130 ALA ALA C . n C 3 131 SER 131 131 131 SER SER C . n C 3 132 VAL 132 132 132 VAL VAL C . n C 3 133 VAL 133 133 133 VAL VAL C . n C 3 134 CYS 134 134 134 CYS CYS C . n C 3 135 LEU 135 135 135 LEU LEU C . n C 3 136 LEU 136 136 136 LEU LEU C . n C 3 137 ASN 137 137 137 ASN ASN C . n C 3 138 ASN 138 138 138 ASN ASN C . n C 3 139 PHE 139 139 139 PHE PHE C . n C 3 140 TYR 140 140 140 TYR TYR C . n C 3 141 PRO 141 141 141 PRO PRO C . n C 3 142 ARG 142 142 142 ARG ARG C . n C 3 143 GLU 143 143 143 GLU GLU C . n C 3 144 ALA 144 144 144 ALA ALA C . n C 3 145 LYS 145 145 145 LYS LYS C . n C 3 146 VAL 146 146 146 VAL VAL C . n C 3 147 GLN 147 147 147 GLN GLN C . n C 3 148 TRP 148 148 148 TRP TRP C . n C 3 149 LYS 149 149 149 LYS LYS C . n C 3 150 VAL 150 150 150 VAL VAL C . n C 3 151 ASP 151 151 151 ASP ASP C . n C 3 152 ASN 152 152 152 ASN ALA C . n C 3 153 ALA 153 153 153 ALA ALA C . n C 3 154 LEU 154 154 154 LEU LEU C . n C 3 155 GLN 155 155 155 GLN ALA C . n C 3 156 SER 156 156 156 SER SER C . n C 3 157 GLY 157 157 157 GLY GLY C . n C 3 158 ASN 158 158 158 ASN ASN C . n C 3 159 SER 159 159 159 SER SER C . n C 3 160 GLN 160 160 160 GLN GLN C . n C 3 161 GLU 161 161 161 GLU GLU C . n C 3 162 SER 162 162 162 SER SER C . n C 3 163 VAL 163 163 163 VAL VAL C . n C 3 164 THR 164 164 164 THR THR C . n C 3 165 GLU 165 165 165 GLU GLU C . n C 3 166 GLN 166 166 166 GLN GLN C . n C 3 167 ASP 167 167 167 ASP ASP C . n C 3 168 SER 168 168 168 SER SER C . n C 3 169 LYS 169 169 169 LYS ALA C . n C 3 170 ASP 170 170 170 ASP ASP C . n C 3 171 SER 171 171 171 SER SER C . n C 3 172 THR 172 172 172 THR THR C . n C 3 173 TYR 173 173 173 TYR TYR C . n C 3 174 SER 174 174 174 SER SER C . n C 3 175 LEU 175 175 175 LEU LEU C . n C 3 176 SER 176 176 176 SER SER C . n C 3 177 SER 177 177 177 SER SER C . n C 3 178 THR 178 178 178 THR THR C . n C 3 179 LEU 179 179 179 LEU LEU C . n C 3 180 THR 180 180 180 THR THR C . n C 3 181 LEU 181 181 181 LEU LEU C . n C 3 182 SER 182 182 182 SER SER C . n C 3 183 LYS 183 183 183 LYS LYS C . n C 3 184 ALA 184 184 184 ALA ALA C . n C 3 185 ASP 185 185 185 ASP ASP C . n C 3 186 TYR 186 186 ? ? ? C . n C 3 187 GLU 187 187 ? ? ? C . n C 3 188 LYS 188 188 ? ? ? C . n C 3 189 HIS 189 189 ? ? ? C . n C 3 190 LYS 190 190 ? ? ? C . n C 3 191 VAL 191 191 191 VAL VAL C . n C 3 192 TYR 192 192 192 TYR ALA C . n C 3 193 ALA 193 193 193 ALA ALA C . n C 3 194 CYS 194 194 194 CYS CYS C . n C 3 195 GLU 195 195 195 GLU GLU C . n C 3 196 VAL 196 196 196 VAL VAL C . n C 3 197 THR 197 197 197 THR THR C . n C 3 198 HIS 198 198 198 HIS HIS C . n C 3 199 GLN 199 199 199 GLN GLN C . n C 3 200 GLY 200 200 200 GLY GLY C . n C 3 201 LEU 201 201 201 LEU LEU C . n C 3 202 SER 202 202 202 SER SER C . n C 3 203 SER 203 203 203 SER SER C . n C 3 204 PRO 204 204 204 PRO PRO C . n C 3 205 VAL 205 205 205 VAL VAL C . n C 3 206 THR 206 206 206 THR THR C . n C 3 207 LYS 207 207 207 LYS LYS C . n C 3 208 SER 208 208 208 SER SER C . n C 3 209 PHE 209 209 209 PHE PHE C . n C 3 210 ASN 210 210 210 ASN ASN C . n C 3 211 ARG 211 211 211 ARG ARG C . n C 3 212 GLY 212 212 ? ? ? C . n C 3 213 GLU 213 213 ? ? ? C . n C 3 214 CYS 214 214 ? ? ? C . n D 4 1 MET 1 -18 ? ? ? D . n D 4 2 GLU 2 -17 ? ? ? D . n D 4 3 PHE 3 -16 ? ? ? D . n D 4 4 GLY 4 -15 ? ? ? D . n D 4 5 LEU 5 -14 ? ? ? D . n D 4 6 SER 6 -13 ? ? ? D . n D 4 7 TRP 7 -12 ? ? ? D . n D 4 8 VAL 8 -11 ? ? ? D . n D 4 9 PHE 9 -10 ? ? ? D . n D 4 10 LEU 10 -9 ? ? ? D . n D 4 11 VAL 11 -8 ? ? ? D . n D 4 12 ALA 12 -7 ? ? ? D . n D 4 13 ILE 13 -6 ? ? ? D . n D 4 14 LEU 14 -5 ? ? ? D . n D 4 15 GLU 15 -4 ? ? ? D . n D 4 16 GLY 16 -3 ? ? ? D . n D 4 17 VAL 17 -2 ? ? ? D . n D 4 18 HIS 18 -1 ? ? ? D . n D 4 19 CYS 19 0 ? ? ? D . n D 4 20 GLU 20 1 1 GLU ALA D . n D 4 21 VAL 21 2 2 VAL VAL D . n D 4 22 GLN 22 3 3 GLN GLN D . n D 4 23 LEU 23 4 4 LEU LEU D . n D 4 24 VAL 24 5 5 VAL VAL D . n D 4 25 GLU 25 6 6 GLU GLU D . n D 4 26 SER 26 7 7 SER SER D . n D 4 27 GLY 27 8 8 GLY GLY D . n D 4 28 GLY 28 9 9 GLY GLY D . n D 4 29 GLY 29 10 10 GLY GLY D . n D 4 30 VAL 30 11 11 VAL VAL D . n D 4 31 VAL 31 12 12 VAL VAL D . n D 4 32 GLN 32 13 13 GLN GLN D . n D 4 33 PRO 33 14 14 PRO PRO D . n D 4 34 GLY 34 15 15 GLY GLY D . n D 4 35 ARG 35 16 16 ARG ALA D . n D 4 36 SER 36 17 17 SER SER D . n D 4 37 LEU 37 18 18 LEU LEU D . n D 4 38 ARG 38 19 19 ARG ARG D . n D 4 39 LEU 39 20 20 LEU LEU D . n D 4 40 SER 40 21 21 SER SER D . n D 4 41 CYS 41 22 22 CYS CYS D . n D 4 42 GLY 42 23 23 GLY GLY D . n D 4 43 ALA 43 24 24 ALA ALA D . n D 4 44 SER 44 25 25 SER SER D . n D 4 45 GLY 45 26 26 GLY GLY D . n D 4 46 PHE 46 27 27 PHE ALA D . n D 4 47 THR 47 28 28 THR THR D . n D 4 48 PHE 48 29 29 PHE PHE D . n D 4 49 ASN 49 30 30 ASN ALA D . n D 4 50 THR 50 31 31 THR THR D . n D 4 51 TYR 51 32 32 TYR TYR D . n D 4 52 ALA 52 33 33 ALA ALA D . n D 4 53 MET 53 34 34 MET MET D . n D 4 54 HIS 54 35 35 HIS HIS D . n D 4 55 TRP 55 36 36 TRP TRP D . n D 4 56 VAL 56 37 37 VAL VAL D . n D 4 57 ARG 57 38 38 ARG ARG D . n D 4 58 GLN 58 39 39 GLN GLN D . n D 4 59 ALA 59 40 40 ALA ALA D . n D 4 60 PRO 60 41 41 PRO PRO D . n D 4 61 GLY 61 42 42 GLY GLY D . n D 4 62 LYS 62 43 43 LYS LYS D . n D 4 63 GLY 63 44 44 GLY GLY D . n D 4 64 VAL 64 45 45 VAL VAL D . n D 4 65 GLU 65 46 46 GLU GLU D . n D 4 66 TRP 66 47 47 TRP TRP D . n D 4 67 VAL 67 48 48 VAL VAL D . n D 4 68 ALA 68 49 49 ALA ALA D . n D 4 69 VAL 69 50 50 VAL VAL D . n D 4 70 VAL 70 51 51 VAL VAL D . n D 4 71 SER 71 52 52 SER SER D . n D 4 72 ASP 72 53 53 ASP ASP D . n D 4 73 GLY 73 54 54 GLY GLY D . n D 4 74 GLY 74 55 55 GLY GLY D . n D 4 75 GLY 75 56 56 GLY GLY D . n D 4 76 ASN 76 57 57 ASN ASN D . n D 4 77 ARG 77 58 58 ARG ALA D . n D 4 78 TYR 78 59 59 TYR TYR D . n D 4 79 TYR 79 60 60 TYR TYR D . n D 4 80 ALA 80 61 61 ALA ALA D . n D 4 81 ALA 81 62 62 ALA ALA D . n D 4 82 SER 82 63 63 SER SER D . n D 4 83 VAL 83 64 64 VAL VAL D . n D 4 84 LYS 84 65 65 LYS ALA D . n D 4 85 GLY 85 66 66 GLY GLY D . n D 4 86 ARG 86 67 67 ARG ALA D . n D 4 87 PHE 87 68 68 PHE PHE D . n D 4 88 THR 88 69 69 THR THR D . n D 4 89 ILE 89 70 70 ILE ILE D . n D 4 90 SER 90 71 71 SER SER D . n D 4 91 ARG 91 72 72 ARG ALA D . n D 4 92 ASP 92 73 73 ASP ASP D . n D 4 93 ASN 93 74 74 ASN ALA D . n D 4 94 SER 94 75 75 SER SER D . n D 4 95 LYS 95 76 76 LYS ALA D . n D 4 96 ASN 96 77 77 ASN ASN D . n D 4 97 THR 97 78 78 THR THR D . n D 4 98 LEU 98 79 79 LEU ALA D . n D 4 99 PHE 99 80 80 PHE PHE D . n D 4 100 LEU 100 81 81 LEU LEU D . n D 4 101 GLN 101 82 82 GLN GLN D . n D 4 102 LEU 102 83 83 LEU LEU D . n D 4 103 ASN 103 84 84 ASN ASN D . n D 4 104 THR 104 85 85 THR THR D . n D 4 105 LEU 105 86 86 LEU LEU D . n D 4 106 ARG 106 87 87 ARG ALA D . n D 4 107 PRO 107 88 88 PRO PRO D . n D 4 108 GLU 108 89 89 GLU GLU D . n D 4 109 ASP 109 90 90 ASP ASP D . n D 4 110 THR 110 91 91 THR THR D . n D 4 111 ALA 111 92 92 ALA ALA D . n D 4 112 VAL 112 93 93 VAL VAL D . n D 4 113 TYR 113 94 94 TYR TYR D . n D 4 114 TYR 114 95 95 TYR TYR D . n D 4 115 CYS 115 96 96 CYS CYS D . n D 4 116 ALA 116 97 97 ALA ALA D . n D 4 117 ARG 117 98 98 ARG ALA D . n D 4 118 SER 118 99 99 SER SER D . n D 4 119 ARG 119 100 100 ARG ARG D . n D 4 120 GLY 120 101 101 GLY GLY D . n D 4 121 ASN 121 102 102 ASN ASN D . n D 4 122 HIS 122 103 103 HIS HIS D . n D 4 123 TYR 123 104 104 TYR TYR D . n D 4 124 TYR 124 105 105 TYR TYR D . n D 4 125 TYR 125 106 106 TYR TYR D . n D 4 126 GLY 126 107 107 GLY GLY D . n D 4 127 MET 127 108 108 MET MET D . n D 4 128 ASP 128 109 109 ASP ALA D . n D 4 129 VAL 129 110 110 VAL VAL D . n D 4 130 TRP 130 111 111 TRP TRP D . n D 4 131 GLY 131 112 112 GLY GLY D . n D 4 132 ARG 132 113 113 ARG ALA D . n D 4 133 GLY 133 114 114 GLY GLY D . n D 4 134 THR 134 115 115 THR THR D . n D 4 135 THR 135 116 116 THR THR D . n D 4 136 VAL 136 117 117 VAL VAL D . n D 4 137 THR 137 118 118 THR THR D . n D 4 138 VAL 138 119 119 VAL VAL D . n D 4 139 SER 139 120 120 SER SER D . n D 4 140 SER 140 121 121 SER SER D . n D 4 141 ALA 141 122 122 ALA ALA D . n D 4 142 SER 142 123 123 SER SER D . n D 4 143 THR 143 124 124 THR THR D . n D 4 144 LYS 144 125 125 LYS LYS D . n D 4 145 GLY 145 126 126 GLY GLY D . n D 4 146 PRO 146 127 127 PRO PRO D . n D 4 147 SER 147 128 128 SER SER D . n D 4 148 VAL 148 129 129 VAL VAL D . n D 4 149 PHE 149 130 130 PHE PHE D . n D 4 150 PRO 150 131 131 PRO PRO D . n D 4 151 LEU 151 132 132 LEU LEU D . n D 4 152 ALA 152 133 133 ALA ALA D . n D 4 153 PRO 153 134 134 PRO PRO D . n D 4 154 SER 154 135 ? ? ? D . n D 4 155 SER 155 136 ? ? ? D . n D 4 156 LYS 156 137 ? ? ? D . n D 4 157 SER 157 138 ? ? ? D . n D 4 158 THR 158 139 ? ? ? D . n D 4 159 SER 159 140 ? ? ? D . n D 4 160 GLY 160 141 ? ? ? D . n D 4 161 GLY 161 142 ? ? ? D . n D 4 162 THR 162 143 ? ? ? D . n D 4 163 ALA 163 144 ? ? ? D . n D 4 164 ALA 164 145 145 ALA ALA D . n D 4 165 LEU 165 146 146 LEU LEU D . n D 4 166 GLY 166 147 147 GLY GLY D . n D 4 167 CYS 167 148 148 CYS CYS D . n D 4 168 LEU 168 149 149 LEU LEU D . n D 4 169 VAL 169 150 150 VAL VAL D . n D 4 170 LYS 170 151 151 LYS LYS D . n D 4 171 ASP 171 152 152 ASP ASP D . n D 4 172 TYR 172 153 153 TYR TYR D . n D 4 173 PHE 173 154 154 PHE PHE D . n D 4 174 PRO 174 155 155 PRO PRO D . n D 4 175 GLU 175 156 156 GLU GLU D . n D 4 176 PRO 176 157 157 PRO PRO D . n D 4 177 VAL 177 158 158 VAL VAL D . n D 4 178 THR 178 159 159 THR THR D . n D 4 179 VAL 179 160 160 VAL VAL D . n D 4 180 SER 180 161 161 SER SER D . n D 4 181 TRP 181 162 162 TRP TRP D . n D 4 182 ASN 182 163 163 ASN ASN D . n D 4 183 SER 183 164 164 SER SER D . n D 4 184 GLY 184 165 165 GLY GLY D . n D 4 185 ALA 185 166 166 ALA ALA D . n D 4 186 LEU 186 167 167 LEU LEU D . n D 4 187 THR 187 168 168 THR THR D . n D 4 188 SER 188 169 169 SER SER D . n D 4 189 GLY 189 170 170 GLY GLY D . n D 4 190 VAL 190 171 171 VAL VAL D . n D 4 191 HIS 191 172 172 HIS HIS D . n D 4 192 THR 192 173 173 THR THR D . n D 4 193 PHE 193 174 174 PHE PHE D . n D 4 194 PRO 194 175 175 PRO PRO D . n D 4 195 ALA 195 176 176 ALA ALA D . n D 4 196 VAL 196 177 177 VAL VAL D . n D 4 197 LEU 197 178 178 LEU LEU D . n D 4 198 GLN 198 179 179 GLN GLN D . n D 4 199 SER 199 180 180 SER SER D . n D 4 200 SER 200 181 181 SER SER D . n D 4 201 GLY 201 182 182 GLY GLY D . n D 4 202 LEU 202 183 183 LEU LEU D . n D 4 203 TYR 203 184 184 TYR TYR D . n D 4 204 SER 204 185 185 SER SER D . n D 4 205 LEU 205 186 186 LEU LEU D . n D 4 206 SER 206 187 187 SER SER D . n D 4 207 SER 207 188 188 SER SER D . n D 4 208 VAL 208 189 189 VAL VAL D . n D 4 209 VAL 209 190 190 VAL VAL D . n D 4 210 THR 210 191 191 THR THR D . n D 4 211 VAL 211 192 192 VAL VAL D . n D 4 212 PRO 212 193 193 PRO PRO D . n D 4 213 SER 213 194 ? ? ? D . n D 4 214 SER 214 195 ? ? ? D . n D 4 215 SER 215 196 ? ? ? D . n D 4 216 LEU 216 197 ? ? ? D . n D 4 217 GLY 217 198 ? ? ? D . n D 4 218 THR 218 199 ? ? ? D . n D 4 219 GLN 219 200 ? ? ? D . n D 4 220 THR 220 201 201 THR THR D . n D 4 221 TYR 221 202 202 TYR TYR D . n D 4 222 ILE 222 203 203 ILE ILE D . n D 4 223 CYS 223 204 204 CYS CYS D . n D 4 224 ASN 224 205 205 ASN ASN D . n D 4 225 VAL 225 206 206 VAL VAL D . n D 4 226 ASN 226 207 207 ASN ASN D . n D 4 227 HIS 227 208 208 HIS HIS D . n D 4 228 LYS 228 209 209 LYS ALA D . n D 4 229 PRO 229 210 210 PRO PRO D . n D 4 230 SER 230 211 211 SER SER D . n D 4 231 ASN 231 212 212 ASN ASN D . n D 4 232 THR 232 213 213 THR THR D . n D 4 233 LYS 233 214 214 LYS LYS D . n D 4 234 VAL 234 215 215 VAL VAL D . n D 4 235 ASP 235 216 216 ASP ASP D . n D 4 236 LYS 236 217 217 LYS LYS D . n D 4 237 ARG 237 218 218 ARG ALA D . n D 4 238 VAL 238 219 219 VAL VAL D . n D 4 239 GLU 239 220 220 GLU GLU D . n D 4 240 PRO 240 221 221 PRO PRO D . n D 4 241 LYS 241 222 222 LYS LYS D . n D 4 242 SER 242 223 223 SER SER D . n D 4 243 CYS 243 224 224 CYS CYS D . n D 4 244 ASP 244 225 225 ASP ASP D . n D 4 245 LYS 245 226 ? ? ? D . n D 4 246 GLY 246 227 ? ? ? D . n D 4 247 SER 247 228 ? ? ? D . n D 4 248 GLU 248 229 ? ? ? D . n D 4 249 ASN 249 230 ? ? ? D . n D 4 250 LEU 250 231 ? ? ? D . n D 4 251 TYR 251 232 ? ? ? D . n D 4 252 PHE 252 233 ? ? ? D . n D 4 253 GLN 253 234 ? ? ? D . n D 4 254 GLY 254 235 ? ? ? D . n D 4 255 SER 255 236 ? ? ? D . n D 4 256 TRP 256 237 ? ? ? D . n D 4 257 SER 257 238 ? ? ? D . n D 4 258 HIS 258 239 ? ? ? D . n D 4 259 PRO 259 240 ? ? ? D . n D 4 260 GLN 260 241 ? ? ? D . n D 4 261 PHE 261 242 ? ? ? D . n D 4 262 GLU 262 243 ? ? ? D . n D 4 263 LYS 263 244 ? ? ? D . n D 4 264 GLY 264 245 ? ? ? D . n D 4 265 GLY 265 246 ? ? ? D . n D 4 266 GLY 266 247 ? ? ? D . n D 4 267 SER 267 248 ? ? ? D . n D 4 268 GLY 268 249 ? ? ? D . n D 4 269 GLY 269 250 ? ? ? D . n D 4 270 GLY 270 251 ? ? ? D . n D 4 271 SER 271 252 ? ? ? D . n D 4 272 GLY 272 253 ? ? ? D . n D 4 273 GLY 273 254 ? ? ? D . n D 4 274 GLY 274 255 ? ? ? D . n D 4 275 SER 275 256 ? ? ? D . n D 4 276 TRP 276 257 ? ? ? D . n D 4 277 SER 277 258 ? ? ? D . n D 4 278 HIS 278 259 ? ? ? D . n D 4 279 PRO 279 260 ? ? ? D . n D 4 280 GLN 280 261 ? ? ? D . n D 4 281 PHE 281 262 ? ? ? D . n D 4 282 GLU 282 263 ? ? ? D . n D 4 283 LYS 283 264 ? ? ? D . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code E 5 NAG 1 901 800 NAG NAG A . F 5 NAG 1 902 900 NAG NAG A . G 5 NAG 1 903 1000 NAG NAG A . H 5 NAG 1 800 800 NAG NAG B . I 5 NAG 2 801 801 NAG NAG B . J 6 BMA 3 802 802 BMA BMA B . K 7 MAN 4 803 803 MAN MAN B . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details tetrameric _pdbx_struct_assembly.oligomeric_count 4 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 14620 ? 1 MORE -67 ? 1 'SSA (A^2)' 53590 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2015-05-13 2 'Structure model' 1 1 2015-05-20 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Database references' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(phenix.refine: 1.8.1_1168)' 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? . 4 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OE1 D GLN 13 ? ? OG D SER 121 ? ? 1.67 2 1 ND2 A ASN 783 ? ? C2 A NAG 903 ? ? 2.11 3 1 OH A TYR 405 ? ? OD2 A ASP 633 ? ? 2.13 4 1 O A MET 576 ? ? OG1 A THR 630 ? ? 2.15 5 1 NH2 B ARG 121 ? ? OD1 D ASN 57 ? ? 2.18 6 1 OD2 A ASP 129 ? ? OG A SER 135 ? ? 2.19 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CA D VAL 119 ? ? C D VAL 119 ? ? N D SER 120 ? ? 134.91 117.20 17.71 2.20 Y 2 1 O D VAL 119 ? ? C D VAL 119 ? ? N D SER 120 ? ? 98.76 122.70 -23.94 1.60 Y # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ARG A 44 ? ? -121.58 -76.15 2 1 SER A 47 ? ? -143.05 -68.35 3 1 THR A 56 ? ? -87.41 -74.34 4 1 GLU A 88 ? ? -95.15 -67.33 5 1 LEU A 146 ? ? 69.52 -12.52 6 1 VAL A 147 ? ? -98.51 -64.43 7 1 PHE A 174 ? ? -109.31 -62.91 8 1 PRO A 180 ? ? -66.22 75.11 9 1 ALA A 204 ? ? -93.55 -66.85 10 1 THR A 216 ? ? -96.31 -64.16 11 1 THR A 238 ? ? -123.00 -58.88 12 1 SER A 304 ? ? -120.31 -63.50 13 1 ASP A 315 ? ? -127.46 -58.99 14 1 ASN A 317 ? ? -101.35 -60.90 15 1 GLU A 386 ? ? 67.62 -2.88 16 1 VAL A 494 ? ? -104.41 -64.13 17 1 SER A 524 ? ? -120.65 -63.51 18 1 SER A 573 ? ? -178.69 149.57 19 1 GLN A 609 ? ? -124.87 -62.46 20 1 TRP A 629 ? ? -86.91 -76.98 21 1 THR A 646 ? ? -55.09 -72.25 22 1 MET A 741 ? ? -114.87 -74.89 23 1 PRO A 768 ? ? -90.00 43.42 24 1 GLU B 55 ? ? -108.72 -65.04 25 1 SER C 30 ? ? -60.14 -71.21 26 1 SER C 31 ? ? -129.65 -69.35 27 1 LEU C 47 ? ? -120.57 -66.47 28 1 ALA C 50 ? ? -126.20 -80.53 29 1 ALA C 51 ? ? -136.38 -67.88 30 1 GLN C 55 ? ? -130.04 -59.24 31 1 SER C 56 ? ? -67.61 -174.75 32 1 THR C 69 ? ? -133.52 -67.65 33 1 ALA C 84 ? ? -172.45 -177.31 34 1 PHE C 98 ? ? 178.31 159.29 35 1 ARG C 108 ? ? -149.86 -121.58 36 1 THR C 109 ? ? -71.68 -148.01 37 1 ASN C 138 ? ? 55.19 70.11 38 1 LYS C 169 ? ? -104.68 -72.17 39 1 ALA C 184 ? ? 52.48 70.24 40 1 PRO C 204 ? ? -65.04 69.08 41 1 VAL D 48 ? ? -121.82 -65.11 42 1 THR D 85 ? ? -122.28 -63.25 43 1 ALA D 92 ? ? -171.61 -176.69 44 1 ARG D 113 ? ? -86.50 -73.90 45 1 ASP D 152 ? ? 57.41 70.27 46 1 PHE D 154 ? ? -179.22 137.63 47 1 ASN D 163 ? ? 53.02 -116.97 48 1 SER D 164 ? ? -113.63 -90.26 # _pdbx_validate_main_chain_plane.id 1 _pdbx_validate_main_chain_plane.PDB_model_num 1 _pdbx_validate_main_chain_plane.auth_comp_id VAL _pdbx_validate_main_chain_plane.auth_asym_id D _pdbx_validate_main_chain_plane.auth_seq_id 119 _pdbx_validate_main_chain_plane.PDB_ins_code ? _pdbx_validate_main_chain_plane.label_alt_id ? _pdbx_validate_main_chain_plane.improper_torsion_angle 19.06 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A ARG 39 ? CG ? A ARG 39 CG 2 1 Y 1 A ARG 39 ? CD ? A ARG 39 CD 3 1 Y 1 A ARG 39 ? NE ? A ARG 39 NE 4 1 Y 1 A ARG 39 ? CZ ? A ARG 39 CZ 5 1 Y 1 A ARG 39 ? NH1 ? A ARG 39 NH1 6 1 Y 1 A ARG 39 ? NH2 ? A ARG 39 NH2 7 1 Y 1 A ARG 44 ? CG ? A ARG 44 CG 8 1 Y 1 A ARG 44 ? CD ? A ARG 44 CD 9 1 Y 1 A ARG 44 ? NE ? A ARG 44 NE 10 1 Y 1 A ARG 44 ? CZ ? A ARG 44 CZ 11 1 Y 1 A ARG 44 ? NH1 ? A ARG 44 NH1 12 1 Y 1 A ARG 44 ? NH2 ? A ARG 44 NH2 13 1 Y 1 A LEU 48 ? CG ? A LEU 48 CG 14 1 Y 1 A LEU 48 ? CD1 ? A LEU 48 CD1 15 1 Y 1 A LEU 48 ? CD2 ? A LEU 48 CD2 16 1 Y 1 A LYS 49 ? CG ? A LYS 49 CG 17 1 Y 1 A LYS 49 ? CD ? A LYS 49 CD 18 1 Y 1 A LYS 49 ? CE ? A LYS 49 CE 19 1 Y 1 A LYS 49 ? NZ ? A LYS 49 NZ 20 1 Y 1 A GLU 51 ? CG ? A GLU 51 CG 21 1 Y 1 A GLU 51 ? CD ? A GLU 51 CD 22 1 Y 1 A GLU 51 ? OE1 ? A GLU 51 OE1 23 1 Y 1 A GLU 51 ? OE2 ? A GLU 51 OE2 24 1 Y 1 A PHE 58 ? CG ? A PHE 58 CG 25 1 Y 1 A PHE 58 ? CD1 ? A PHE 58 CD1 26 1 Y 1 A PHE 58 ? CD2 ? A PHE 58 CD2 27 1 Y 1 A PHE 58 ? CE1 ? A PHE 58 CE1 28 1 Y 1 A PHE 58 ? CE2 ? A PHE 58 CE2 29 1 Y 1 A PHE 58 ? CZ ? A PHE 58 CZ 30 1 Y 1 A GLU 61 ? CG ? A GLU 61 CG 31 1 Y 1 A GLU 61 ? CD ? A GLU 61 CD 32 1 Y 1 A GLU 61 ? OE1 ? A GLU 61 OE1 33 1 Y 1 A GLU 61 ? OE2 ? A GLU 61 OE2 34 1 Y 1 A LEU 62 ? CG ? A LEU 62 CG 35 1 Y 1 A LEU 62 ? CD1 ? A LEU 62 CD1 36 1 Y 1 A LEU 62 ? CD2 ? A LEU 62 CD2 37 1 Y 1 A ILE 63 ? CG1 ? A ILE 63 CG1 38 1 Y 1 A ILE 63 ? CG2 ? A ILE 63 CG2 39 1 Y 1 A ILE 63 ? CD1 ? A ILE 63 CD1 40 1 Y 1 A LYS 64 ? CG ? A LYS 64 CG 41 1 Y 1 A LYS 64 ? CD ? A LYS 64 CD 42 1 Y 1 A LYS 64 ? CE ? A LYS 64 CE 43 1 Y 1 A LYS 64 ? NZ ? A LYS 64 NZ 44 1 Y 1 A LEU 66 ? CG ? A LEU 66 CG 45 1 Y 1 A LEU 66 ? CD1 ? A LEU 66 CD1 46 1 Y 1 A LEU 66 ? CD2 ? A LEU 66 CD2 47 1 Y 1 A THR 85 ? OG1 ? A THR 85 OG1 48 1 Y 1 A THR 85 ? CG2 ? A THR 85 CG2 49 1 Y 1 A THR 86 ? OG1 ? A THR 86 OG1 50 1 Y 1 A THR 86 ? CG2 ? A THR 86 CG2 51 1 Y 1 A HIS 87 ? CG ? A HIS 87 CG 52 1 Y 1 A HIS 87 ? ND1 ? A HIS 87 ND1 53 1 Y 1 A HIS 87 ? CD2 ? A HIS 87 CD2 54 1 Y 1 A HIS 87 ? CE1 ? A HIS 87 CE1 55 1 Y 1 A HIS 87 ? NE2 ? A HIS 87 NE2 56 1 Y 1 A GLU 88 ? CG ? A GLU 88 CG 57 1 Y 1 A GLU 88 ? CD ? A GLU 88 CD 58 1 Y 1 A GLU 88 ? OE1 ? A GLU 88 OE1 59 1 Y 1 A GLU 88 ? OE2 ? A GLU 88 OE2 60 1 Y 1 A TYR 104 ? CG ? A TYR 104 CG 61 1 Y 1 A TYR 104 ? CD1 ? A TYR 104 CD1 62 1 Y 1 A TYR 104 ? CD2 ? A TYR 104 CD2 63 1 Y 1 A TYR 104 ? CE1 ? A TYR 104 CE1 64 1 Y 1 A TYR 104 ? CE2 ? A TYR 104 CE2 65 1 Y 1 A TYR 104 ? CZ ? A TYR 104 CZ 66 1 Y 1 A TYR 104 ? OH ? A TYR 104 OH 67 1 Y 1 A PHE 119 ? CG ? A PHE 119 CG 68 1 Y 1 A PHE 119 ? CD1 ? A PHE 119 CD1 69 1 Y 1 A PHE 119 ? CD2 ? A PHE 119 CD2 70 1 Y 1 A PHE 119 ? CE1 ? A PHE 119 CE1 71 1 Y 1 A PHE 119 ? CE2 ? A PHE 119 CE2 72 1 Y 1 A PHE 119 ? CZ ? A PHE 119 CZ 73 1 Y 1 A LYS 187 ? CG ? A LYS 187 CG 74 1 Y 1 A LYS 187 ? CD ? A LYS 187 CD 75 1 Y 1 A LYS 187 ? CE ? A LYS 187 CE 76 1 Y 1 A LYS 187 ? NZ ? A LYS 187 NZ 77 1 Y 1 A ASN 188 ? CG ? A ASN 188 CG 78 1 Y 1 A ASN 188 ? OD1 ? A ASN 188 OD1 79 1 Y 1 A ASN 188 ? ND2 ? A ASN 188 ND2 80 1 Y 1 A THR 189 ? OG1 ? A THR 189 OG1 81 1 Y 1 A THR 189 ? CG2 ? A THR 189 CG2 82 1 Y 1 A HIS 193 ? CG ? A HIS 193 CG 83 1 Y 1 A HIS 193 ? ND1 ? A HIS 193 ND1 84 1 Y 1 A HIS 193 ? CD2 ? A HIS 193 CD2 85 1 Y 1 A HIS 193 ? CE1 ? A HIS 193 CE1 86 1 Y 1 A HIS 193 ? NE2 ? A HIS 193 NE2 87 1 Y 1 A GLN 293 ? CG ? A GLN 293 CG 88 1 Y 1 A GLN 293 ? CD ? A GLN 293 CD 89 1 Y 1 A GLN 293 ? OE1 ? A GLN 293 OE1 90 1 Y 1 A GLN 293 ? NE2 ? A GLN 293 NE2 91 1 Y 1 A SER 319 ? OG ? A SER 319 OG 92 1 Y 1 A LYS 320 ? CG ? A LYS 320 CG 93 1 Y 1 A LYS 320 ? CD ? A LYS 320 CD 94 1 Y 1 A LYS 320 ? CE ? A LYS 320 CE 95 1 Y 1 A LYS 320 ? NZ ? A LYS 320 NZ 96 1 Y 1 A THR 323 ? OG1 ? A THR 323 OG1 97 1 Y 1 A THR 323 ? CG2 ? A THR 323 CG2 98 1 Y 1 A HIS 357 ? CG ? A HIS 357 CG 99 1 Y 1 A HIS 357 ? ND1 ? A HIS 357 ND1 100 1 Y 1 A HIS 357 ? CD2 ? A HIS 357 CD2 101 1 Y 1 A HIS 357 ? CE1 ? A HIS 357 CE1 102 1 Y 1 A HIS 357 ? NE2 ? A HIS 357 NE2 103 1 Y 1 A GLN 443 ? CG ? A GLN 443 CG 104 1 Y 1 A GLN 443 ? CD ? A GLN 443 CD 105 1 Y 1 A GLN 443 ? OE1 ? A GLN 443 OE1 106 1 Y 1 A GLN 443 ? NE2 ? A GLN 443 NE2 107 1 Y 1 A ARG 525 ? CG ? A ARG 525 CG 108 1 Y 1 A ARG 525 ? CD ? A ARG 525 CD 109 1 Y 1 A ARG 525 ? NE ? A ARG 525 NE 110 1 Y 1 A ARG 525 ? CZ ? A ARG 525 CZ 111 1 Y 1 A ARG 525 ? NH1 ? A ARG 525 NH1 112 1 Y 1 A ARG 525 ? NH2 ? A ARG 525 NH2 113 1 Y 1 A GLU 612 ? CG ? A GLU 612 CG 114 1 Y 1 A GLU 612 ? CD ? A GLU 612 CD 115 1 Y 1 A GLU 612 ? OE1 ? A GLU 612 OE1 116 1 Y 1 A GLU 612 ? OE2 ? A GLU 612 OE2 117 1 Y 1 A GLN 648 ? CG ? A GLN 648 CG 118 1 Y 1 A GLN 648 ? CD ? A GLN 648 CD 119 1 Y 1 A GLN 648 ? OE1 ? A GLN 648 OE1 120 1 Y 1 A GLN 648 ? NE2 ? A GLN 648 NE2 121 1 Y 1 A MET 758 ? CG ? A MET 758 CG 122 1 Y 1 A MET 758 ? SD ? A MET 758 SD 123 1 Y 1 A MET 758 ? CE ? A MET 758 CE 124 1 Y 1 B THR 29 ? OG1 ? B THR 7 OG1 125 1 Y 1 B THR 29 ? CG2 ? B THR 7 CG2 126 1 Y 1 B PRO 30 ? CG ? B PRO 8 CG 127 1 Y 1 B PRO 30 ? CD ? B PRO 8 CD 128 1 Y 1 B LEU 31 ? CG ? B LEU 9 CG 129 1 Y 1 B LEU 31 ? CD1 ? B LEU 9 CD1 130 1 Y 1 B LEU 31 ? CD2 ? B LEU 9 CD2 131 1 Y 1 B GLU 55 ? CG ? B GLU 33 CG 132 1 Y 1 B GLU 55 ? CD ? B GLU 33 CD 133 1 Y 1 B GLU 55 ? OE1 ? B GLU 33 OE1 134 1 Y 1 B GLU 55 ? OE2 ? B GLU 33 OE2 135 1 Y 1 C SER 30 ? OG ? C SER 30 OG 136 1 Y 1 C SER 31 ? OG ? C SER 31 OG 137 1 Y 1 C GLN 37 ? CG ? C GLN 37 CG 138 1 Y 1 C GLN 37 ? CD ? C GLN 37 CD 139 1 Y 1 C GLN 37 ? OE1 ? C GLN 37 OE1 140 1 Y 1 C GLN 37 ? NE2 ? C GLN 37 NE2 141 1 Y 1 C LYS 42 ? CG ? C LYS 42 CG 142 1 Y 1 C LYS 42 ? CD ? C LYS 42 CD 143 1 Y 1 C LYS 42 ? CE ? C LYS 42 CE 144 1 Y 1 C LYS 42 ? NZ ? C LYS 42 NZ 145 1 Y 1 C GLN 90 ? CG ? C GLN 90 CG 146 1 Y 1 C GLN 90 ? CD ? C GLN 90 CD 147 1 Y 1 C GLN 90 ? OE1 ? C GLN 90 OE1 148 1 Y 1 C GLN 90 ? NE2 ? C GLN 90 NE2 149 1 Y 1 C ASN 93 ? CG ? C ASN 93 CG 150 1 Y 1 C ASN 93 ? OD1 ? C ASN 93 OD1 151 1 Y 1 C ASN 93 ? ND2 ? C ASN 93 ND2 152 1 Y 1 C ASN 152 ? CG ? C ASN 152 CG 153 1 Y 1 C ASN 152 ? OD1 ? C ASN 152 OD1 154 1 Y 1 C ASN 152 ? ND2 ? C ASN 152 ND2 155 1 Y 1 C GLN 155 ? CG ? C GLN 155 CG 156 1 Y 1 C GLN 155 ? CD ? C GLN 155 CD 157 1 Y 1 C GLN 155 ? OE1 ? C GLN 155 OE1 158 1 Y 1 C GLN 155 ? NE2 ? C GLN 155 NE2 159 1 Y 1 C LYS 169 ? CG ? C LYS 169 CG 160 1 Y 1 C LYS 169 ? CD ? C LYS 169 CD 161 1 Y 1 C LYS 169 ? CE ? C LYS 169 CE 162 1 Y 1 C LYS 169 ? NZ ? C LYS 169 NZ 163 1 Y 1 C TYR 192 ? CG ? C TYR 192 CG 164 1 Y 1 C TYR 192 ? CD1 ? C TYR 192 CD1 165 1 Y 1 C TYR 192 ? CD2 ? C TYR 192 CD2 166 1 Y 1 C TYR 192 ? CE1 ? C TYR 192 CE1 167 1 Y 1 C TYR 192 ? CE2 ? C TYR 192 CE2 168 1 Y 1 C TYR 192 ? CZ ? C TYR 192 CZ 169 1 Y 1 C TYR 192 ? OH ? C TYR 192 OH 170 1 Y 1 D GLU 1 ? CG ? D GLU 20 CG 171 1 Y 1 D GLU 1 ? CD ? D GLU 20 CD 172 1 Y 1 D GLU 1 ? OE1 ? D GLU 20 OE1 173 1 Y 1 D GLU 1 ? OE2 ? D GLU 20 OE2 174 1 Y 1 D ARG 16 ? CG ? D ARG 35 CG 175 1 Y 1 D ARG 16 ? CD ? D ARG 35 CD 176 1 Y 1 D ARG 16 ? NE ? D ARG 35 NE 177 1 Y 1 D ARG 16 ? CZ ? D ARG 35 CZ 178 1 Y 1 D ARG 16 ? NH1 ? D ARG 35 NH1 179 1 Y 1 D ARG 16 ? NH2 ? D ARG 35 NH2 180 1 Y 1 D PHE 27 ? CG ? D PHE 46 CG 181 1 Y 1 D PHE 27 ? CD1 ? D PHE 46 CD1 182 1 Y 1 D PHE 27 ? CD2 ? D PHE 46 CD2 183 1 Y 1 D PHE 27 ? CE1 ? D PHE 46 CE1 184 1 Y 1 D PHE 27 ? CE2 ? D PHE 46 CE2 185 1 Y 1 D PHE 27 ? CZ ? D PHE 46 CZ 186 1 Y 1 D ASN 30 ? CG ? D ASN 49 CG 187 1 Y 1 D ASN 30 ? OD1 ? D ASN 49 OD1 188 1 Y 1 D ASN 30 ? ND2 ? D ASN 49 ND2 189 1 Y 1 D ARG 58 ? CG ? D ARG 77 CG 190 1 Y 1 D ARG 58 ? CD ? D ARG 77 CD 191 1 Y 1 D ARG 58 ? NE ? D ARG 77 NE 192 1 Y 1 D ARG 58 ? CZ ? D ARG 77 CZ 193 1 Y 1 D ARG 58 ? NH1 ? D ARG 77 NH1 194 1 Y 1 D ARG 58 ? NH2 ? D ARG 77 NH2 195 1 Y 1 D LYS 65 ? CG ? D LYS 84 CG 196 1 Y 1 D LYS 65 ? CD ? D LYS 84 CD 197 1 Y 1 D LYS 65 ? CE ? D LYS 84 CE 198 1 Y 1 D LYS 65 ? NZ ? D LYS 84 NZ 199 1 Y 1 D ARG 67 ? CG ? D ARG 86 CG 200 1 Y 1 D ARG 67 ? CD ? D ARG 86 CD 201 1 Y 1 D ARG 67 ? NE ? D ARG 86 NE 202 1 Y 1 D ARG 67 ? CZ ? D ARG 86 CZ 203 1 Y 1 D ARG 67 ? NH1 ? D ARG 86 NH1 204 1 Y 1 D ARG 67 ? NH2 ? D ARG 86 NH2 205 1 Y 1 D ARG 72 ? CG ? D ARG 91 CG 206 1 Y 1 D ARG 72 ? CD ? D ARG 91 CD 207 1 Y 1 D ARG 72 ? NE ? D ARG 91 NE 208 1 Y 1 D ARG 72 ? CZ ? D ARG 91 CZ 209 1 Y 1 D ARG 72 ? NH1 ? D ARG 91 NH1 210 1 Y 1 D ARG 72 ? NH2 ? D ARG 91 NH2 211 1 Y 1 D ASN 74 ? CG ? D ASN 93 CG 212 1 Y 1 D ASN 74 ? OD1 ? D ASN 93 OD1 213 1 Y 1 D ASN 74 ? ND2 ? D ASN 93 ND2 214 1 Y 1 D LYS 76 ? CG ? D LYS 95 CG 215 1 Y 1 D LYS 76 ? CD ? D LYS 95 CD 216 1 Y 1 D LYS 76 ? CE ? D LYS 95 CE 217 1 Y 1 D LYS 76 ? NZ ? D LYS 95 NZ 218 1 Y 1 D LEU 79 ? CG ? D LEU 98 CG 219 1 Y 1 D LEU 79 ? CD1 ? D LEU 98 CD1 220 1 Y 1 D LEU 79 ? CD2 ? D LEU 98 CD2 221 1 Y 1 D ARG 87 ? CG ? D ARG 106 CG 222 1 Y 1 D ARG 87 ? CD ? D ARG 106 CD 223 1 Y 1 D ARG 87 ? NE ? D ARG 106 NE 224 1 Y 1 D ARG 87 ? CZ ? D ARG 106 CZ 225 1 Y 1 D ARG 87 ? NH1 ? D ARG 106 NH1 226 1 Y 1 D ARG 87 ? NH2 ? D ARG 106 NH2 227 1 Y 1 D ARG 98 ? CG ? D ARG 117 CG 228 1 Y 1 D ARG 98 ? CD ? D ARG 117 CD 229 1 Y 1 D ARG 98 ? NE ? D ARG 117 NE 230 1 Y 1 D ARG 98 ? CZ ? D ARG 117 CZ 231 1 Y 1 D ARG 98 ? NH1 ? D ARG 117 NH1 232 1 Y 1 D ARG 98 ? NH2 ? D ARG 117 NH2 233 1 Y 1 D ASP 109 ? CG ? D ASP 128 CG 234 1 Y 1 D ASP 109 ? OD1 ? D ASP 128 OD1 235 1 Y 1 D ASP 109 ? OD2 ? D ASP 128 OD2 236 1 Y 1 D ARG 113 ? CG ? D ARG 132 CG 237 1 Y 1 D ARG 113 ? CD ? D ARG 132 CD 238 1 Y 1 D ARG 113 ? NE ? D ARG 132 NE 239 1 Y 1 D ARG 113 ? CZ ? D ARG 132 CZ 240 1 Y 1 D ARG 113 ? NH1 ? D ARG 132 NH1 241 1 Y 1 D ARG 113 ? NH2 ? D ARG 132 NH2 242 1 Y 1 D LYS 209 ? CG ? D LYS 228 CG 243 1 Y 1 D LYS 209 ? CD ? D LYS 228 CD 244 1 Y 1 D LYS 209 ? CE ? D LYS 228 CE 245 1 Y 1 D LYS 209 ? NZ ? D LYS 228 NZ 246 1 Y 1 D ARG 218 ? CG ? D ARG 237 CG 247 1 Y 1 D ARG 218 ? CD ? D ARG 237 CD 248 1 Y 1 D ARG 218 ? NE ? D ARG 237 NE 249 1 Y 1 D ARG 218 ? CZ ? D ARG 237 CZ 250 1 Y 1 D ARG 218 ? NH1 ? D ARG 237 NH1 251 1 Y 1 D ARG 218 ? NH2 ? D ARG 237 NH2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A MET 1 ? A MET 1 2 1 Y 1 A PHE 2 ? A PHE 2 3 1 Y 1 A ALA 3 ? A ALA 3 4 1 Y 1 A LEU 4 ? A LEU 4 5 1 Y 1 A VAL 5 ? A VAL 5 6 1 Y 1 A LEU 6 ? A LEU 6 7 1 Y 1 A ALA 7 ? A ALA 7 8 1 Y 1 A VAL 8 ? A VAL 8 9 1 Y 1 A VAL 9 ? A VAL 9 10 1 Y 1 A ILE 10 ? A ILE 10 11 1 Y 1 A LEU 11 ? A LEU 11 12 1 Y 1 A PRO 12 ? A PRO 12 13 1 Y 1 A LEU 13 ? A LEU 13 14 1 Y 1 A TRP 14 ? A TRP 14 15 1 Y 1 A THR 15 ? A THR 15 16 1 Y 1 A THR 16 ? A THR 16 17 1 Y 1 A ALA 17 ? A ALA 17 18 1 Y 1 A ASN 18 ? A ASN 18 19 1 Y 1 A LYS 19 ? A LYS 19 20 1 Y 1 A SER 20 ? A SER 20 21 1 Y 1 A TYR 21 ? A TYR 21 22 1 Y 1 A VAL 22 ? A VAL 22 23 1 Y 1 A THR 23 ? A THR 23 24 1 Y 1 A PRO 24 ? A PRO 24 25 1 Y 1 A THR 25 ? A THR 25 26 1 Y 1 A PRO 26 ? A PRO 26 27 1 Y 1 A ALA 27 ? A ALA 27 28 1 Y 1 A THR 28 ? A THR 28 29 1 Y 1 A ARG 29 ? A ARG 29 30 1 Y 1 A SER 30 ? A SER 30 31 1 Y 1 A ILE 31 ? A ILE 31 32 1 Y 1 A GLY 32 ? A GLY 32 33 1 Y 1 A HIS 33 ? A HIS 33 34 1 Y 1 A MET 34 ? A MET 34 35 1 Y 1 A SER 35 ? A SER 35 36 1 Y 1 A HIS 105 ? A HIS 105 37 1 Y 1 A PHE 106 ? A PHE 106 38 1 Y 1 A LYS 107 ? A LYS 107 39 1 Y 1 A ALA 108 ? A ALA 108 40 1 Y 1 A GLU 109 ? A GLU 109 41 1 Y 1 A HIS 110 ? A HIS 110 42 1 Y 1 A ARG 111 ? A ARG 111 43 1 Y 1 A ALA 112 ? A ALA 112 44 1 Y 1 A PRO 113 ? A PRO 113 45 1 Y 1 A PHE 114 ? A PHE 114 46 1 Y 1 A PRO 115 ? A PRO 115 47 1 Y 1 A ALA 116 ? A ALA 116 48 1 Y 1 A GLY 117 ? A GLY 117 49 1 Y 1 A ARG 118 ? A ARG 118 50 1 Y 1 A VAL 444 ? A VAL 444 51 1 Y 1 A LYS 445 ? A LYS 445 52 1 Y 1 A PRO 446 ? A PRO 446 53 1 Y 1 A ALA 447 ? A ALA 447 54 1 Y 1 A ASN 448 ? A ASN 448 55 1 Y 1 A VAL 449 ? A VAL 449 56 1 Y 1 A ASP 450 ? A ASP 450 57 1 Y 1 A TYR 451 ? A TYR 451 58 1 Y 1 A ARG 517 ? A ARG 517 59 1 Y 1 A GLU 518 ? A GLU 518 60 1 Y 1 A GLY 519 ? A GLY 519 61 1 Y 1 A LEU 520 ? A LEU 520 62 1 Y 1 A GLU 521 ? A GLU 521 63 1 Y 1 A ASN 522 ? A ASN 522 64 1 Y 1 A PHE 792 ? A PHE 792 65 1 Y 1 A GLU 793 ? A GLU 793 66 1 Y 1 A ARG 794 ? A ARG 794 67 1 Y 1 A ARG 795 ? A ARG 795 68 1 Y 1 A GLY 796 ? A GLY 796 69 1 Y 1 A SER 797 ? A SER 797 70 1 Y 1 A GLU 798 ? A GLU 798 71 1 Y 1 A ASN 799 ? A ASN 799 72 1 Y 1 A LEU 800 ? A LEU 800 73 1 Y 1 A TYR 801 ? A TYR 801 74 1 Y 1 A PHE 802 ? A PHE 802 75 1 Y 1 A GLN 803 ? A GLN 803 76 1 Y 1 A GLY 804 ? A GLY 804 77 1 Y 1 A SER 805 ? A SER 805 78 1 Y 1 A TRP 806 ? A TRP 806 79 1 Y 1 A SER 807 ? A SER 807 80 1 Y 1 A HIS 808 ? A HIS 808 81 1 Y 1 A PRO 809 ? A PRO 809 82 1 Y 1 A GLN 810 ? A GLN 810 83 1 Y 1 A PHE 811 ? A PHE 811 84 1 Y 1 A GLU 812 ? A GLU 812 85 1 Y 1 A LYS 813 ? A LYS 813 86 1 Y 1 A GLY 814 ? A GLY 814 87 1 Y 1 A GLY 815 ? A GLY 815 88 1 Y 1 A GLY 816 ? A GLY 816 89 1 Y 1 A SER 817 ? A SER 817 90 1 Y 1 A GLY 818 ? A GLY 818 91 1 Y 1 A GLY 819 ? A GLY 819 92 1 Y 1 A GLY 820 ? A GLY 820 93 1 Y 1 A SER 821 ? A SER 821 94 1 Y 1 A GLY 822 ? A GLY 822 95 1 Y 1 A GLY 823 ? A GLY 823 96 1 Y 1 A GLY 824 ? A GLY 824 97 1 Y 1 A SER 825 ? A SER 825 98 1 Y 1 A TRP 826 ? A TRP 826 99 1 Y 1 A SER 827 ? A SER 827 100 1 Y 1 A HIS 828 ? A HIS 828 101 1 Y 1 A PRO 829 ? A PRO 829 102 1 Y 1 A GLN 830 ? A GLN 830 103 1 Y 1 A PHE 831 ? A PHE 831 104 1 Y 1 A GLU 832 ? A GLU 832 105 1 Y 1 A LYS 833 ? A LYS 833 106 1 Y 1 B LEU 23 ? B LEU 1 107 1 Y 1 B HIS 24 ? B HIS 2 108 1 Y 1 B LEU 25 ? B LEU 3 109 1 Y 1 B GLN 26 ? B GLN 4 110 1 Y 1 B ASP 27 ? B ASP 5 111 1 Y 1 B ASP 28 ? B ASP 6 112 1 Y 1 C TYR 186 ? C TYR 186 113 1 Y 1 C GLU 187 ? C GLU 187 114 1 Y 1 C LYS 188 ? C LYS 188 115 1 Y 1 C HIS 189 ? C HIS 189 116 1 Y 1 C LYS 190 ? C LYS 190 117 1 Y 1 C GLY 212 ? C GLY 212 118 1 Y 1 C GLU 213 ? C GLU 213 119 1 Y 1 C CYS 214 ? C CYS 214 120 1 Y 1 D MET -18 ? D MET 1 121 1 Y 1 D GLU -17 ? D GLU 2 122 1 Y 1 D PHE -16 ? D PHE 3 123 1 Y 1 D GLY -15 ? D GLY 4 124 1 Y 1 D LEU -14 ? D LEU 5 125 1 Y 1 D SER -13 ? D SER 6 126 1 Y 1 D TRP -12 ? D TRP 7 127 1 Y 1 D VAL -11 ? D VAL 8 128 1 Y 1 D PHE -10 ? D PHE 9 129 1 Y 1 D LEU -9 ? D LEU 10 130 1 Y 1 D VAL -8 ? D VAL 11 131 1 Y 1 D ALA -7 ? D ALA 12 132 1 Y 1 D ILE -6 ? D ILE 13 133 1 Y 1 D LEU -5 ? D LEU 14 134 1 Y 1 D GLU -4 ? D GLU 15 135 1 Y 1 D GLY -3 ? D GLY 16 136 1 Y 1 D VAL -2 ? D VAL 17 137 1 Y 1 D HIS -1 ? D HIS 18 138 1 Y 1 D CYS 0 ? D CYS 19 139 1 Y 1 D SER 135 ? D SER 154 140 1 Y 1 D SER 136 ? D SER 155 141 1 Y 1 D LYS 137 ? D LYS 156 142 1 Y 1 D SER 138 ? D SER 157 143 1 Y 1 D THR 139 ? D THR 158 144 1 Y 1 D SER 140 ? D SER 159 145 1 Y 1 D GLY 141 ? D GLY 160 146 1 Y 1 D GLY 142 ? D GLY 161 147 1 Y 1 D THR 143 ? D THR 162 148 1 Y 1 D ALA 144 ? D ALA 163 149 1 Y 1 D SER 194 ? D SER 213 150 1 Y 1 D SER 195 ? D SER 214 151 1 Y 1 D SER 196 ? D SER 215 152 1 Y 1 D LEU 197 ? D LEU 216 153 1 Y 1 D GLY 198 ? D GLY 217 154 1 Y 1 D THR 199 ? D THR 218 155 1 Y 1 D GLN 200 ? D GLN 219 156 1 Y 1 D LYS 226 ? D LYS 245 157 1 Y 1 D GLY 227 ? D GLY 246 158 1 Y 1 D SER 228 ? D SER 247 159 1 Y 1 D GLU 229 ? D GLU 248 160 1 Y 1 D ASN 230 ? D ASN 249 161 1 Y 1 D LEU 231 ? D LEU 250 162 1 Y 1 D TYR 232 ? D TYR 251 163 1 Y 1 D PHE 233 ? D PHE 252 164 1 Y 1 D GLN 234 ? D GLN 253 165 1 Y 1 D GLY 235 ? D GLY 254 166 1 Y 1 D SER 236 ? D SER 255 167 1 Y 1 D TRP 237 ? D TRP 256 168 1 Y 1 D SER 238 ? D SER 257 169 1 Y 1 D HIS 239 ? D HIS 258 170 1 Y 1 D PRO 240 ? D PRO 259 171 1 Y 1 D GLN 241 ? D GLN 260 172 1 Y 1 D PHE 242 ? D PHE 261 173 1 Y 1 D GLU 243 ? D GLU 262 174 1 Y 1 D LYS 244 ? D LYS 263 175 1 Y 1 D GLY 245 ? D GLY 264 176 1 Y 1 D GLY 246 ? D GLY 265 177 1 Y 1 D GLY 247 ? D GLY 266 178 1 Y 1 D SER 248 ? D SER 267 179 1 Y 1 D GLY 249 ? D GLY 268 180 1 Y 1 D GLY 250 ? D GLY 269 181 1 Y 1 D GLY 251 ? D GLY 270 182 1 Y 1 D SER 252 ? D SER 271 183 1 Y 1 D GLY 253 ? D GLY 272 184 1 Y 1 D GLY 254 ? D GLY 273 185 1 Y 1 D GLY 255 ? D GLY 274 186 1 Y 1 D SER 256 ? D SER 275 187 1 Y 1 D TRP 257 ? D TRP 276 188 1 Y 1 D SER 258 ? D SER 277 189 1 Y 1 D HIS 259 ? D HIS 278 190 1 Y 1 D PRO 260 ? D PRO 279 191 1 Y 1 D GLN 261 ? D GLN 280 192 1 Y 1 D PHE 262 ? D PHE 281 193 1 Y 1 D GLU 263 ? D GLU 282 194 1 Y 1 D LYS 264 ? D LYS 283 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 5 N-ACETYL-D-GLUCOSAMINE NAG 6 BETA-D-MANNOSE BMA 7 ALPHA-D-MANNOSE MAN #