data_4UM1 # _entry.id 4UM1 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4UM1 PDBE EBI-60625 WWPDB D_1290060625 # _pdbx_database_related.db_name PDB _pdbx_database_related.db_id 4UM3 _pdbx_database_related.content_type unspecified _pdbx_database_related.details 'ENGINEERED LS-ACHBP WITH ALPHA4-ALPHA4 INTERFACE IN COMPLEX WITH NS3920' # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 4UM1 _pdbx_database_status.deposit_site PDBE _pdbx_database_status.process_site PDBE _pdbx_database_status.SG_entry . _pdbx_database_status.recvd_initial_deposition_date 2014-05-14 _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Shahsavar, A.' 1 'Kastrup, J.S.' 2 'Balle, T.' 3 'Gajhede, M.' 4 # _citation.id primary _citation.title ;Achbp Engineered to Mimic the Alpha4-Alpha4 Binding Pocket in Alpha4Beta2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity ; _citation.journal_abbrev Mol.Pharmacol. _citation.journal_volume 88 _citation.page_first 697 _citation.page_last ? _citation.year 2015 _citation.journal_id_ASTM MOPMA3 _citation.country US _citation.journal_id_ISSN 0026-895X _citation.journal_id_CSD 0197 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 26180047 _citation.pdbx_database_id_DOI 10.1124/MOL.115.098061 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Shahsavar, A.' 1 primary 'Ahring, P.K.' 2 primary 'Olsen, J.A.' 3 primary 'Krintel, C.' 4 primary 'Kastrup, J.S.' 5 primary 'Balle, T.' 6 primary 'Gajhede, M.' 7 # _cell.entry_id 4UM1 _cell.length_a 77.328 _cell.length_b 123.104 _cell.length_c 127.450 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 20 _cell.pdbx_unique_axis ? # _symmetry.entry_id 4UM1 _symmetry.space_group_name_H-M 'P 21 21 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 18 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'ACETYLCHOLINE-BINDING PROTEIN' 26053.143 5 ? YES ? '1-(5-ETHOXYPYRIDIN-3-YL)-1,4-DIAZEPANE (NS3573) BINDS AT THE INTERFACE OF EACH TWO MONOMERS' 2 non-polymer syn '1-(5-ethoxypyridin-3-yl)-1,4-diazepane' 221.299 5 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 4 water nat water 18.015 116 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'ACH-BINDING PROTEIN, ACHBP' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDR TLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLAHVVSDGEVQYTPSIRQRFSCDVSGVDTESGATCRIKIG SWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL ; _entity_poly.pdbx_seq_one_letter_code_can ;MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDR TLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLAHVVSDGEVQYTPSIRQRFSCDVSGVDTESGATCRIKIG SWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL ; _entity_poly.pdbx_strand_id A,B,C,D,E _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 MET n 1 2 ARG n 1 3 ARG n 1 4 ASN n 1 5 ILE n 1 6 PHE n 1 7 CYS n 1 8 LEU n 1 9 ALA n 1 10 CYS n 1 11 LEU n 1 12 TRP n 1 13 ILE n 1 14 VAL n 1 15 GLN n 1 16 ALA n 1 17 CYS n 1 18 LEU n 1 19 SER n 1 20 LEU n 1 21 ASP n 1 22 ARG n 1 23 ALA n 1 24 ASP n 1 25 ILE n 1 26 LEU n 1 27 TYR n 1 28 ASN n 1 29 ILE n 1 30 ARG n 1 31 GLN n 1 32 THR n 1 33 SER n 1 34 ARG n 1 35 PRO n 1 36 ASP n 1 37 VAL n 1 38 ILE n 1 39 PRO n 1 40 THR n 1 41 GLN n 1 42 ARG n 1 43 ASP n 1 44 ARG n 1 45 PRO n 1 46 VAL n 1 47 ALA n 1 48 VAL n 1 49 SER n 1 50 VAL n 1 51 SER n 1 52 LEU n 1 53 LYS n 1 54 PHE n 1 55 ILE n 1 56 ASN n 1 57 ILE n 1 58 LEU n 1 59 GLU n 1 60 VAL n 1 61 ASN n 1 62 GLU n 1 63 ILE n 1 64 THR n 1 65 ASN n 1 66 GLU n 1 67 VAL n 1 68 ASP n 1 69 VAL n 1 70 VAL n 1 71 PHE n 1 72 TRP n 1 73 GLN n 1 74 GLN n 1 75 THR n 1 76 THR n 1 77 TRP n 1 78 SER n 1 79 ASP n 1 80 ARG n 1 81 THR n 1 82 LEU n 1 83 ALA n 1 84 TRP n 1 85 ASN n 1 86 SER n 1 87 SER n 1 88 HIS n 1 89 SER n 1 90 PRO n 1 91 ASP n 1 92 GLN n 1 93 VAL n 1 94 SER n 1 95 VAL n 1 96 PRO n 1 97 ILE n 1 98 SER n 1 99 SER n 1 100 LEU n 1 101 TRP n 1 102 VAL n 1 103 PRO n 1 104 ASP n 1 105 LEU n 1 106 ALA n 1 107 ALA n 1 108 TYR n 1 109 ASN n 1 110 ALA n 1 111 ILE n 1 112 SER n 1 113 LYS n 1 114 PRO n 1 115 GLU n 1 116 VAL n 1 117 LEU n 1 118 THR n 1 119 PRO n 1 120 GLN n 1 121 LEU n 1 122 ALA n 1 123 HIS n 1 124 VAL n 1 125 VAL n 1 126 SER n 1 127 ASP n 1 128 GLY n 1 129 GLU n 1 130 VAL n 1 131 GLN n 1 132 TYR n 1 133 THR n 1 134 PRO n 1 135 SER n 1 136 ILE n 1 137 ARG n 1 138 GLN n 1 139 ARG n 1 140 PHE n 1 141 SER n 1 142 CYS n 1 143 ASP n 1 144 VAL n 1 145 SER n 1 146 GLY n 1 147 VAL n 1 148 ASP n 1 149 THR n 1 150 GLU n 1 151 SER n 1 152 GLY n 1 153 ALA n 1 154 THR n 1 155 CYS n 1 156 ARG n 1 157 ILE n 1 158 LYS n 1 159 ILE n 1 160 GLY n 1 161 SER n 1 162 TRP n 1 163 THR n 1 164 HIS n 1 165 HIS n 1 166 SER n 1 167 ARG n 1 168 GLU n 1 169 ILE n 1 170 SER n 1 171 VAL n 1 172 ASP n 1 173 PRO n 1 174 THR n 1 175 THR n 1 176 GLU n 1 177 ASN n 1 178 SER n 1 179 ASP n 1 180 ASP n 1 181 SER n 1 182 GLU n 1 183 TYR n 1 184 PHE n 1 185 SER n 1 186 GLN n 1 187 TYR n 1 188 SER n 1 189 ARG n 1 190 PHE n 1 191 GLU n 1 192 ILE n 1 193 LEU n 1 194 ASP n 1 195 VAL n 1 196 THR n 1 197 GLN n 1 198 LYS n 1 199 LYS n 1 200 ASN n 1 201 SER n 1 202 VAL n 1 203 THR n 1 204 TYR n 1 205 SER n 1 206 CYS n 1 207 CYS n 1 208 PRO n 1 209 GLU n 1 210 ALA n 1 211 TYR n 1 212 GLU n 1 213 ASP n 1 214 VAL n 1 215 GLU n 1 216 VAL n 1 217 SER n 1 218 LEU n 1 219 ASN n 1 220 PHE n 1 221 ARG n 1 222 LYS n 1 223 LYS n 1 224 GLY n 1 225 ARG n 1 226 SER n 1 227 GLU n 1 228 ILE n 1 229 LEU n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'GREAT POND SNAIL' _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene ? _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'LYMNAEA STAGNALIS' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 6523 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'FALL ARMYWORM' _entity_src_gen.pdbx_host_org_scientific_name 'SPODOPTERA FRUGIPERDA' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7108 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain SF9 _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type BACULOVIRUS _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name PFASTBAC _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code ACHP_LYMST _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ? _struct_ref.pdbx_align_begin ? _struct_ref.pdbx_db_accession P58154 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4UM1 A 1 ? 229 ? P58154 1 ? 229 ? -18 210 2 1 4UM1 B 1 ? 229 ? P58154 1 ? 229 ? -18 210 3 1 4UM1 C 1 ? 229 ? P58154 1 ? 229 ? -18 210 4 1 4UM1 D 1 ? 229 ? P58154 1 ? 229 ? -18 210 5 1 4UM1 E 1 ? 229 ? P58154 1 ? 229 ? -18 210 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4UM1 HIS A 123 ? UNP P58154 ARG 123 'engineered mutation' 104 1 1 4UM1 GLN A 131 ? UNP P58154 LEU 131 'engineered mutation' 112 2 1 4UM1 THR A 133 ? UNP P58154 MET 133 'engineered mutation' 114 3 2 4UM1 HIS B 123 ? UNP P58154 ARG 123 'engineered mutation' 104 4 2 4UM1 GLN B 131 ? UNP P58154 LEU 131 'engineered mutation' 112 5 2 4UM1 THR B 133 ? UNP P58154 MET 133 'engineered mutation' 114 6 3 4UM1 HIS C 123 ? UNP P58154 ARG 123 'engineered mutation' 104 7 3 4UM1 GLN C 131 ? UNP P58154 LEU 131 'engineered mutation' 112 8 3 4UM1 THR C 133 ? UNP P58154 MET 133 'engineered mutation' 114 9 4 4UM1 HIS D 123 ? UNP P58154 ARG 123 'engineered mutation' 104 10 4 4UM1 GLN D 131 ? UNP P58154 LEU 131 'engineered mutation' 112 11 4 4UM1 THR D 133 ? UNP P58154 MET 133 'engineered mutation' 114 12 5 4UM1 HIS E 123 ? UNP P58154 ARG 123 'engineered mutation' 104 13 5 4UM1 GLN E 131 ? UNP P58154 LEU 131 'engineered mutation' 112 14 5 4UM1 THR E 133 ? UNP P58154 MET 133 'engineered mutation' 114 15 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight 09P non-polymer . '1-(5-ethoxypyridin-3-yl)-1,4-diazepane' ? 'C12 H19 N3 O' 221.299 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 4UM1 _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.43 _exptl_crystal.density_percent_sol 49.34 _exptl_crystal.description NONE # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method ? _exptl_crystal_grow.temp ? _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 8 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '0.1 M TRIS BASE (PH 8.0), 1-3% V/V POLYETHYLENE GLYCOL (PEG) 400 AND 1.8-2.3 M (NH4)2SO4' # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'MARMOSAIC 225 mm CCD' _diffrn_detector.pdbx_collection_date ? _diffrn_detector.details MIRRORS # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'SI(111)' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ESRF BEAMLINE ID23-2' _diffrn_source.pdbx_synchrotron_site ESRF _diffrn_source.pdbx_synchrotron_beamline ID23-2 _diffrn_source.pdbx_wavelength 1 _diffrn_source.pdbx_wavelength_list ? # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 4UM1 _reflns.observed_criterion_sigma_I 0.0 _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 49.18 _reflns.d_resolution_high 2.83 _reflns.number_obs 29761 _reflns.number_all ? _reflns.percent_possible_obs 100.0 _reflns.pdbx_Rmerge_I_obs 0.21 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 10.50 _reflns.B_iso_Wilson_estimate 51.25 _reflns.pdbx_redundancy 7.8 # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 2.83 _reflns_shell.d_res_low 2.98 _reflns_shell.percent_possible_all 100.0 _reflns_shell.Rmerge_I_obs 1.37 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 2.00 _reflns_shell.pdbx_redundancy 7.9 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 4UM1 _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 29726 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.16 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 49.178 _refine.ls_d_res_high 2.830 _refine.ls_percent_reflns_obs 99.99 _refine.ls_R_factor_obs 0.1948 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.1928 _refine.ls_R_factor_R_free 0.2307 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.1 _refine.ls_number_reflns_R_free 2839 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 35 _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_ls_cross_valid_method ? _refine.details ? _refine.pdbx_starting_model 'PDB ENTRY 3U8K' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.39 _refine.pdbx_overall_phase_error 23.85 _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8020 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 94 _refine_hist.number_atoms_solvent 116 _refine_hist.number_atoms_total 8230 _refine_hist.d_res_high 2.830 _refine_hist.d_res_low 49.178 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function f_bond_d 0.010 ? ? 8320 'X-RAY DIFFRACTION' ? f_angle_d 1.096 ? ? 11335 'X-RAY DIFFRACTION' ? f_dihedral_angle_d 13.283 ? ? 3000 'X-RAY DIFFRACTION' ? f_chiral_restr 0.072 ? ? 1289 'X-RAY DIFFRACTION' ? f_plane_restr 0.004 ? ? 1455 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_all _refine_ls_shell.R_factor_all 'X-RAY DIFFRACTION' . 2.8300 2.8788 2689 0.3293 100.00 0.4454 . . 109 . . 'X-RAY DIFFRACTION' . 2.8788 2.9312 2668 0.3175 100.00 0.3350 . . 124 . . 'X-RAY DIFFRACTION' . 2.9312 2.9875 2666 0.2943 100.00 0.3683 . . 163 . . 'X-RAY DIFFRACTION' . 2.9875 3.0485 2636 0.2865 100.00 0.3052 . . 151 . . 'X-RAY DIFFRACTION' . 3.0485 3.1148 2661 0.2730 100.00 0.3255 . . 151 . . 'X-RAY DIFFRACTION' . 3.1148 3.1872 2654 0.2603 100.00 0.3077 . . 129 . . 'X-RAY DIFFRACTION' . 3.1872 3.2669 2655 0.2291 100.00 0.3294 . . 155 . . 'X-RAY DIFFRACTION' . 3.2669 3.3552 2704 0.2099 100.00 0.2537 . . 119 . . 'X-RAY DIFFRACTION' . 3.3552 3.4539 2650 0.2011 100.00 0.2223 . . 156 . . 'X-RAY DIFFRACTION' . 3.4539 3.5654 2630 0.1982 100.00 0.2465 . . 142 . . 'X-RAY DIFFRACTION' . 3.5654 3.6928 2671 0.1856 100.00 0.2534 . . 146 . . 'X-RAY DIFFRACTION' . 3.6928 3.8406 2712 0.1784 100.00 0.1787 . . 101 . . 'X-RAY DIFFRACTION' . 3.8406 4.0153 2634 0.1694 100.00 0.2298 . . 150 . . 'X-RAY DIFFRACTION' . 4.0153 4.2269 2668 0.1503 100.00 0.2091 . . 143 . . 'X-RAY DIFFRACTION' . 4.2269 4.4916 2666 0.1384 100.00 0.1725 . . 135 . . 'X-RAY DIFFRACTION' . 4.4916 4.8381 2649 0.1403 100.00 0.1603 . . 168 . . 'X-RAY DIFFRACTION' . 4.8381 5.3244 2645 0.1554 100.00 0.2052 . . 158 . . 'X-RAY DIFFRACTION' . 5.3244 6.0937 2637 0.1737 100.00 0.2029 . . 157 . . 'X-RAY DIFFRACTION' . 6.0937 7.6727 2668 0.1997 100.00 0.2322 . . 143 . . 'X-RAY DIFFRACTION' . 7.6727 49.1852 2654 0.1927 100.00 0.1819 . . 139 . . # _struct.entry_id 4UM1 _struct.title 'Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3573' _struct.pdbx_descriptor 'ACETYLCHOLINE-BINDING PROTEIN' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 4UM1 _struct_keywords.pdbx_keywords 'SIGNALING PROTEIN' _struct_keywords.text 'SIGNALING PROTEIN, ION CHANNEL, RECEPTOR STOICHIOMETRY, CYS-LOOP RECEPTOR, ACETYLCHOLINE BINDING PROTEIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 1 ? D N N 1 ? E N N 1 ? F N N 2 ? G N N 2 ? H N N 2 ? I N N 2 ? J N N 3 ? K N N 2 ? L N N 4 ? M N N 4 ? N N N 4 ? O N N 4 ? P N N 4 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ASP A 21 ? SER A 33 ? ASP A 2 SER A 14 1 ? 13 HELX_P HELX_P2 2 ARG A 80 ? ALA A 83 ? ARG A 61 ALA A 64 5 ? 4 HELX_P HELX_P3 3 SER A 98 ? LEU A 100 ? SER A 79 LEU A 81 5 ? 3 HELX_P HELX_P4 4 ASP B 21 ? SER B 33 ? ASP B 2 SER B 14 1 ? 13 HELX_P HELX_P5 5 ARG B 80 ? ALA B 83 ? ARG B 61 ALA B 64 5 ? 4 HELX_P HELX_P6 6 SER B 98 ? LEU B 100 ? SER B 79 LEU B 81 5 ? 3 HELX_P HELX_P7 7 ASP C 21 ? SER C 33 ? ASP C 2 SER C 14 1 ? 13 HELX_P HELX_P8 8 ARG C 80 ? ALA C 83 ? ARG C 61 ALA C 64 5 ? 4 HELX_P HELX_P9 9 SER C 98 ? LEU C 100 ? SER C 79 LEU C 81 5 ? 3 HELX_P HELX_P10 10 ASP D 21 ? SER D 33 ? ASP D 2 SER D 14 1 ? 13 HELX_P HELX_P11 11 ARG D 80 ? ALA D 83 ? ARG D 61 ALA D 64 5 ? 4 HELX_P HELX_P12 12 SER D 98 ? LEU D 100 ? SER D 79 LEU D 81 5 ? 3 HELX_P HELX_P13 13 ASP D 180 ? PHE D 184 ? ASP D 161 PHE D 165 5 ? 5 HELX_P HELX_P14 14 ASP E 21 ? SER E 33 ? ASP E 2 SER E 14 1 ? 13 HELX_P HELX_P15 15 ARG E 80 ? ALA E 83 ? ARG E 61 ALA E 64 5 ? 4 HELX_P HELX_P16 16 SER E 98 ? LEU E 100 ? SER E 79 LEU E 81 5 ? 3 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 142 SG ? ? ? 1_555 A CYS 155 SG ? ? A CYS 123 A CYS 136 1_555 ? ? ? ? ? ? ? 2.049 ? disulf2 disulf ? ? A CYS 206 SG ? ? ? 1_555 A CYS 207 SG ? ? A CYS 187 A CYS 188 1_555 ? ? ? ? ? ? ? 2.054 ? disulf3 disulf ? ? B CYS 142 SG ? ? ? 1_555 B CYS 155 SG ? ? B CYS 123 B CYS 136 1_555 ? ? ? ? ? ? ? 2.044 ? disulf4 disulf ? ? B CYS 206 SG ? ? ? 1_555 B CYS 207 SG ? ? B CYS 187 B CYS 188 1_555 ? ? ? ? ? ? ? 2.056 ? disulf5 disulf ? ? C CYS 142 SG ? ? ? 1_555 C CYS 155 SG ? ? C CYS 123 C CYS 136 1_555 ? ? ? ? ? ? ? 2.049 ? disulf6 disulf ? ? C CYS 206 SG ? ? ? 1_555 C CYS 207 SG ? ? C CYS 187 C CYS 188 1_555 ? ? ? ? ? ? ? 2.055 ? disulf7 disulf ? ? D CYS 142 SG ? ? ? 1_555 D CYS 155 SG ? ? D CYS 123 D CYS 136 1_555 ? ? ? ? ? ? ? 2.042 ? disulf8 disulf ? ? D CYS 206 SG ? ? ? 1_555 D CYS 207 SG ? ? D CYS 187 D CYS 188 1_555 ? ? ? ? ? ? ? 2.050 ? disulf9 disulf ? ? E CYS 142 SG ? ? ? 1_555 E CYS 155 SG ? ? E CYS 123 E CYS 136 1_555 ? ? ? ? ? ? ? 2.044 ? disulf10 disulf ? ? E CYS 206 SG A ? ? 1_555 E CYS 207 SG ? ? E CYS 187 E CYS 188 1_555 ? ? ? ? ? ? ? 2.042 ? covale1 covale ? ? D ASN 85 ND2 ? ? ? 1_555 J NAG . C1 ? ? D ASN 66 D NAG 1206 1_555 ? ? ? ? ? ? ? 2.017 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA ? 6 ? AB ? 6 ? AC ? 4 ? BA ? 6 ? BB ? 6 ? BC ? 4 ? CA ? 6 ? CB ? 6 ? CC ? 4 ? DA ? 6 ? DB ? 6 ? DC ? 4 ? EA ? 6 ? EB ? 6 ? EC ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA 1 2 ? anti-parallel AA 2 3 ? anti-parallel AA 3 4 ? anti-parallel AA 4 5 ? parallel AA 5 6 ? anti-parallel AB 1 2 ? anti-parallel AB 2 3 ? anti-parallel AB 3 4 ? anti-parallel AB 4 5 ? anti-parallel AB 5 6 ? parallel AC 1 2 ? anti-parallel AC 2 3 ? anti-parallel AC 3 4 ? anti-parallel BA 1 2 ? anti-parallel BA 2 3 ? anti-parallel BA 3 4 ? anti-parallel BA 4 5 ? parallel BA 5 6 ? anti-parallel BB 1 2 ? anti-parallel BB 2 3 ? anti-parallel BB 3 4 ? anti-parallel BB 4 5 ? anti-parallel BB 5 6 ? parallel BC 1 2 ? anti-parallel BC 2 3 ? anti-parallel BC 3 4 ? anti-parallel CA 1 2 ? anti-parallel CA 2 3 ? anti-parallel CA 3 4 ? anti-parallel CA 4 5 ? parallel CA 5 6 ? anti-parallel CB 1 2 ? anti-parallel CB 2 3 ? anti-parallel CB 3 4 ? anti-parallel CB 4 5 ? anti-parallel CB 5 6 ? parallel CC 1 2 ? anti-parallel CC 2 3 ? anti-parallel CC 3 4 ? anti-parallel DA 1 2 ? anti-parallel DA 2 3 ? anti-parallel DA 3 4 ? anti-parallel DA 4 5 ? parallel DA 5 6 ? anti-parallel DB 1 2 ? anti-parallel DB 2 3 ? anti-parallel DB 3 4 ? anti-parallel DB 4 5 ? anti-parallel DB 5 6 ? parallel DC 1 2 ? anti-parallel DC 2 3 ? anti-parallel DC 3 4 ? anti-parallel EA 1 2 ? anti-parallel EA 2 3 ? anti-parallel EA 3 4 ? anti-parallel EA 4 5 ? parallel EA 5 6 ? anti-parallel EB 1 2 ? anti-parallel EB 2 3 ? anti-parallel EB 3 4 ? anti-parallel EB 4 5 ? anti-parallel EB 5 6 ? parallel EC 1 2 ? anti-parallel EC 2 3 ? anti-parallel EC 3 4 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA 1 GLN A 92 ? PRO A 96 ? GLN A 73 PRO A 77 AA 2 LEU A 121 ? VAL A 125 ? LEU A 102 VAL A 106 AA 3 GLU A 129 ? TYR A 132 ? GLU A 110 TYR A 113 AA 4 GLU A 66 ? SER A 78 ? GLU A 47 SER A 59 AA 5 SER A 135 ? SER A 141 ? SER A 116 SER A 122 AA 6 GLU A 115 ? VAL A 116 ? GLU A 96 VAL A 97 AB 1 GLN A 92 ? PRO A 96 ? GLN A 73 PRO A 77 AB 2 LEU A 121 ? VAL A 125 ? LEU A 102 VAL A 106 AB 3 GLU A 129 ? TYR A 132 ? GLU A 110 TYR A 113 AB 4 GLU A 66 ? SER A 78 ? GLU A 47 SER A 59 AB 5 VAL A 46 ? ILE A 57 ? VAL A 27 ILE A 38 AB 6 ILE A 169 ? PRO A 173 ? ILE A 150 PRO A 154 AC 1 LEU A 105 ? ALA A 107 ? LEU A 86 ALA A 88 AC 2 ALA A 153 ? SER A 161 ? ALA A 134 SER A 142 AC 3 ALA A 210 ? LYS A 222 ? ALA A 191 LYS A 203 AC 4 PHE A 190 ? THR A 203 ? PHE A 171 THR A 184 BA 1 GLN B 92 ? PRO B 96 ? GLN B 73 PRO B 77 BA 2 LEU B 121 ? VAL B 125 ? LEU B 102 VAL B 106 BA 3 GLU B 129 ? TYR B 132 ? GLU B 110 TYR B 113 BA 4 GLU B 66 ? SER B 78 ? GLU B 47 SER B 59 BA 5 SER B 135 ? SER B 141 ? SER B 116 SER B 122 BA 6 GLU B 115 ? VAL B 116 ? GLU B 96 VAL B 97 BB 1 GLN B 92 ? PRO B 96 ? GLN B 73 PRO B 77 BB 2 LEU B 121 ? VAL B 125 ? LEU B 102 VAL B 106 BB 3 GLU B 129 ? TYR B 132 ? GLU B 110 TYR B 113 BB 4 GLU B 66 ? SER B 78 ? GLU B 47 SER B 59 BB 5 VAL B 46 ? ILE B 57 ? VAL B 27 ILE B 38 BB 6 ILE B 169 ? PRO B 173 ? ILE B 150 PRO B 154 BC 1 LEU B 105 ? ALA B 107 ? LEU B 86 ALA B 88 BC 2 ALA B 153 ? SER B 161 ? ALA B 134 SER B 142 BC 3 ALA B 210 ? LYS B 222 ? ALA B 191 LYS B 203 BC 4 PHE B 190 ? THR B 203 ? PHE B 171 THR B 184 CA 1 GLN C 92 ? PRO C 96 ? GLN C 73 PRO C 77 CA 2 LEU C 121 ? VAL C 125 ? LEU C 102 VAL C 106 CA 3 GLU C 129 ? TYR C 132 ? GLU C 110 TYR C 113 CA 4 GLU C 66 ? SER C 78 ? GLU C 47 SER C 59 CA 5 SER C 135 ? SER C 141 ? SER C 116 SER C 122 CA 6 GLU C 115 ? VAL C 116 ? GLU C 96 VAL C 97 CB 1 GLN C 92 ? PRO C 96 ? GLN C 73 PRO C 77 CB 2 LEU C 121 ? VAL C 125 ? LEU C 102 VAL C 106 CB 3 GLU C 129 ? TYR C 132 ? GLU C 110 TYR C 113 CB 4 GLU C 66 ? SER C 78 ? GLU C 47 SER C 59 CB 5 VAL C 46 ? ILE C 57 ? VAL C 27 ILE C 38 CB 6 ILE C 169 ? PRO C 173 ? ILE C 150 PRO C 154 CC 1 LEU C 105 ? ALA C 107 ? LEU C 86 ALA C 88 CC 2 ALA C 153 ? SER C 161 ? ALA C 134 SER C 142 CC 3 ALA C 210 ? LYS C 222 ? ALA C 191 LYS C 203 CC 4 PHE C 190 ? THR C 203 ? PHE C 171 THR C 184 DA 1 GLN D 92 ? PRO D 96 ? GLN D 73 PRO D 77 DA 2 LEU D 121 ? VAL D 125 ? LEU D 102 VAL D 106 DA 3 GLU D 129 ? TYR D 132 ? GLU D 110 TYR D 113 DA 4 GLU D 66 ? SER D 78 ? GLU D 47 SER D 59 DA 5 SER D 135 ? SER D 141 ? SER D 116 SER D 122 DA 6 GLU D 115 ? VAL D 116 ? GLU D 96 VAL D 97 DB 1 GLN D 92 ? PRO D 96 ? GLN D 73 PRO D 77 DB 2 LEU D 121 ? VAL D 125 ? LEU D 102 VAL D 106 DB 3 GLU D 129 ? TYR D 132 ? GLU D 110 TYR D 113 DB 4 GLU D 66 ? SER D 78 ? GLU D 47 SER D 59 DB 5 VAL D 46 ? ILE D 57 ? VAL D 27 ILE D 38 DB 6 ILE D 169 ? PRO D 173 ? ILE D 150 PRO D 154 DC 1 LEU D 105 ? ALA D 107 ? LEU D 86 ALA D 88 DC 2 ALA D 153 ? SER D 161 ? ALA D 134 SER D 142 DC 3 ALA D 210 ? LYS D 222 ? ALA D 191 LYS D 203 DC 4 PHE D 190 ? THR D 203 ? PHE D 171 THR D 184 EA 1 GLN E 92 ? PRO E 96 ? GLN E 73 PRO E 77 EA 2 LEU E 121 ? VAL E 125 ? LEU E 102 VAL E 106 EA 3 GLU E 129 ? TYR E 132 ? GLU E 110 TYR E 113 EA 4 GLU E 66 ? SER E 78 ? GLU E 47 SER E 59 EA 5 SER E 135 ? SER E 141 ? SER E 116 SER E 122 EA 6 GLU E 115 ? VAL E 116 ? GLU E 96 VAL E 97 EB 1 GLN E 92 ? PRO E 96 ? GLN E 73 PRO E 77 EB 2 LEU E 121 ? VAL E 125 ? LEU E 102 VAL E 106 EB 3 GLU E 129 ? TYR E 132 ? GLU E 110 TYR E 113 EB 4 GLU E 66 ? SER E 78 ? GLU E 47 SER E 59 EB 5 VAL E 46 ? ILE E 57 ? VAL E 27 ILE E 38 EB 6 ILE E 169 ? PRO E 173 ? ILE E 150 PRO E 154 EC 1 LEU E 105 ? ALA E 107 ? LEU E 86 ALA E 88 EC 2 ALA E 153 ? SER E 161 ? ALA E 134 SER E 142 EC 3 ALA E 210 ? LYS E 222 ? ALA E 191 LYS E 203 EC 4 PHE E 190 ? THR E 203 ? PHE E 171 THR E 184 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA 1 2 N VAL A 95 ? N VAL A 76 O ALA A 122 ? O ALA A 103 AA 2 3 N VAL A 125 ? N VAL A 106 O GLU A 129 ? O GLU A 110 AA 3 4 N TYR A 132 ? N TYR A 113 O THR A 75 ? O THR A 56 AA 4 5 N PHE A 71 ? N PHE A 52 O ILE A 136 ? O ILE A 117 AA 5 6 N ARG A 137 ? N ARG A 118 O GLU A 115 ? O GLU A 96 AB 1 2 N VAL A 95 ? N VAL A 76 O ALA A 122 ? O ALA A 103 AB 2 3 N VAL A 125 ? N VAL A 106 O GLU A 129 ? O GLU A 110 AB 3 4 N TYR A 132 ? N TYR A 113 O THR A 75 ? O THR A 56 AB 4 5 N THR A 76 ? N THR A 57 O SER A 49 ? O SER A 30 AB 5 6 N VAL A 48 ? N VAL A 29 O SER A 170 ? O SER A 151 AC 1 2 N ALA A 106 ? N ALA A 87 O GLY A 160 ? O GLY A 141 AC 2 3 N SER A 161 ? N SER A 142 O GLU A 212 ? O GLU A 193 AC 3 4 N ARG A 221 ? N ARG A 202 O GLU A 191 ? O GLU A 172 BA 1 2 N VAL B 95 ? N VAL B 76 O ALA B 122 ? O ALA B 103 BA 2 3 N VAL B 125 ? N VAL B 106 O GLU B 129 ? O GLU B 110 BA 3 4 N TYR B 132 ? N TYR B 113 O THR B 75 ? O THR B 56 BA 4 5 N PHE B 71 ? N PHE B 52 O ILE B 136 ? O ILE B 117 BA 5 6 N ARG B 137 ? N ARG B 118 O GLU B 115 ? O GLU B 96 BB 1 2 N VAL B 95 ? N VAL B 76 O ALA B 122 ? O ALA B 103 BB 2 3 N VAL B 125 ? N VAL B 106 O GLU B 129 ? O GLU B 110 BB 3 4 N TYR B 132 ? N TYR B 113 O THR B 75 ? O THR B 56 BB 4 5 N THR B 76 ? N THR B 57 O SER B 49 ? O SER B 30 BB 5 6 N VAL B 48 ? N VAL B 29 O SER B 170 ? O SER B 151 BC 1 2 N ALA B 106 ? N ALA B 87 O GLY B 160 ? O GLY B 141 BC 2 3 N SER B 161 ? N SER B 142 O GLU B 212 ? O GLU B 193 BC 3 4 N ARG B 221 ? N ARG B 202 O GLU B 191 ? O GLU B 172 CA 1 2 N VAL C 95 ? N VAL C 76 O ALA C 122 ? O ALA C 103 CA 2 3 N VAL C 125 ? N VAL C 106 O GLU C 129 ? O GLU C 110 CA 3 4 N TYR C 132 ? N TYR C 113 O THR C 75 ? O THR C 56 CA 4 5 N PHE C 71 ? N PHE C 52 O ILE C 136 ? O ILE C 117 CA 5 6 N ARG C 137 ? N ARG C 118 O GLU C 115 ? O GLU C 96 CB 1 2 N VAL C 95 ? N VAL C 76 O ALA C 122 ? O ALA C 103 CB 2 3 N VAL C 125 ? N VAL C 106 O GLU C 129 ? O GLU C 110 CB 3 4 N TYR C 132 ? N TYR C 113 O THR C 75 ? O THR C 56 CB 4 5 N THR C 76 ? N THR C 57 O SER C 49 ? O SER C 30 CB 5 6 N VAL C 48 ? N VAL C 29 O SER C 170 ? O SER C 151 CC 1 2 N ALA C 106 ? N ALA C 87 O GLY C 160 ? O GLY C 141 CC 2 3 N SER C 161 ? N SER C 142 O GLU C 212 ? O GLU C 193 CC 3 4 N ARG C 221 ? N ARG C 202 O GLU C 191 ? O GLU C 172 DA 1 2 N VAL D 95 ? N VAL D 76 O ALA D 122 ? O ALA D 103 DA 2 3 N VAL D 125 ? N VAL D 106 O GLU D 129 ? O GLU D 110 DA 3 4 N TYR D 132 ? N TYR D 113 O THR D 75 ? O THR D 56 DA 4 5 N PHE D 71 ? N PHE D 52 O ILE D 136 ? O ILE D 117 DA 5 6 N ARG D 137 ? N ARG D 118 O GLU D 115 ? O GLU D 96 DB 1 2 N VAL D 95 ? N VAL D 76 O ALA D 122 ? O ALA D 103 DB 2 3 N VAL D 125 ? N VAL D 106 O GLU D 129 ? O GLU D 110 DB 3 4 N TYR D 132 ? N TYR D 113 O THR D 75 ? O THR D 56 DB 4 5 N THR D 76 ? N THR D 57 O SER D 49 ? O SER D 30 DB 5 6 N VAL D 48 ? N VAL D 29 O SER D 170 ? O SER D 151 DC 1 2 N ALA D 106 ? N ALA D 87 O GLY D 160 ? O GLY D 141 DC 2 3 N SER D 161 ? N SER D 142 O GLU D 212 ? O GLU D 193 DC 3 4 N ARG D 221 ? N ARG D 202 O GLU D 191 ? O GLU D 172 EA 1 2 N VAL E 95 ? N VAL E 76 O ALA E 122 ? O ALA E 103 EA 2 3 N VAL E 125 ? N VAL E 106 O GLU E 129 ? O GLU E 110 EA 3 4 N TYR E 132 ? N TYR E 113 O THR E 75 ? O THR E 56 EA 4 5 N PHE E 71 ? N PHE E 52 O ILE E 136 ? O ILE E 117 EA 5 6 N ARG E 137 ? N ARG E 118 O GLU E 115 ? O GLU E 96 EB 1 2 N VAL E 95 ? N VAL E 76 O ALA E 122 ? O ALA E 103 EB 2 3 N VAL E 125 ? N VAL E 106 O GLU E 129 ? O GLU E 110 EB 3 4 N TYR E 132 ? N TYR E 113 O THR E 75 ? O THR E 56 EB 4 5 N THR E 76 ? N THR E 57 O SER E 49 ? O SER E 30 EB 5 6 N VAL E 48 ? N VAL E 29 O SER E 170 ? O SER E 151 EC 1 2 N ALA E 106 ? N ALA E 87 O GLY E 160 ? O GLY E 141 EC 2 3 N SER E 161 ? N SER E 142 O GLU E 212 ? O GLU E 193 EC 3 4 N ARG E 221 ? N ARG E 202 O GLU E 191 ? O GLU E 172 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE 09P A 211' AC2 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE 09P B 211' AC3 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE 09P C 211' AC4 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE 09P D 211' AC5 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE 09P E 211' AC6 Software ? ? ? ? 3 'Binding site for Mono-Saccharide NAG D1206 bound to ASN D 66' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 7 TYR A 108 ? TYR A 89 . ? 1_555 ? 2 AC1 7 TRP A 162 ? TRP A 143 . ? 1_555 ? 3 AC1 7 CYS A 207 ? CYS A 188 . ? 1_555 ? 4 AC1 7 TYR A 211 ? TYR A 192 . ? 1_555 ? 5 AC1 7 HIS B 123 ? HIS B 104 . ? 1_555 ? 6 AC1 7 GLN B 131 ? GLN B 112 . ? 1_555 ? 7 AC1 7 THR B 133 ? THR B 114 . ? 1_555 ? 8 AC2 8 TYR B 108 ? TYR B 89 . ? 1_555 ? 9 AC2 8 TRP B 162 ? TRP B 143 . ? 1_555 ? 10 AC2 8 TYR B 204 ? TYR B 185 . ? 1_555 ? 11 AC2 8 CYS B 207 ? CYS B 188 . ? 1_555 ? 12 AC2 8 TRP C 72 ? TRP C 53 . ? 1_555 ? 13 AC2 8 HIS C 123 ? HIS C 104 . ? 1_555 ? 14 AC2 8 GLN C 131 ? GLN C 112 . ? 1_555 ? 15 AC2 8 THR C 133 ? THR C 114 . ? 1_555 ? 16 AC3 8 TYR C 108 ? TYR C 89 . ? 1_555 ? 17 AC3 8 TRP C 162 ? TRP C 143 . ? 1_555 ? 18 AC3 8 TYR C 204 ? TYR C 185 . ? 1_555 ? 19 AC3 8 CYS C 207 ? CYS C 188 . ? 1_555 ? 20 AC3 8 TYR C 211 ? TYR C 192 . ? 1_555 ? 21 AC3 8 HOH N . ? HOH C 2017 . ? 1_555 ? 22 AC3 8 HIS D 123 ? HIS D 104 . ? 1_555 ? 23 AC3 8 THR D 133 ? THR D 114 . ? 1_555 ? 24 AC4 8 TYR D 108 ? TYR D 89 . ? 1_555 ? 25 AC4 8 TRP D 162 ? TRP D 143 . ? 1_555 ? 26 AC4 8 TYR D 204 ? TYR D 185 . ? 1_555 ? 27 AC4 8 CYS D 207 ? CYS D 188 . ? 1_555 ? 28 AC4 8 HOH O . ? HOH D 2026 . ? 1_555 ? 29 AC4 8 HIS E 123 ? HIS E 104 . ? 1_555 ? 30 AC4 8 GLN E 131 ? GLN E 112 . ? 1_555 ? 31 AC4 8 THR E 133 ? THR E 114 . ? 1_555 ? 32 AC5 9 TRP A 72 ? TRP A 53 . ? 1_555 ? 33 AC5 9 HIS A 123 ? HIS A 104 . ? 1_555 ? 34 AC5 9 GLN A 131 ? GLN A 112 . ? 1_555 ? 35 AC5 9 THR A 133 ? THR A 114 . ? 1_555 ? 36 AC5 9 HOH L . ? HOH A 2017 . ? 1_555 ? 37 AC5 9 TYR E 108 ? TYR E 89 . ? 1_555 ? 38 AC5 9 TRP E 162 ? TRP E 143 . ? 1_555 ? 39 AC5 9 TYR E 204 ? TYR E 185 . ? 1_555 ? 40 AC5 9 TYR E 211 ? TYR E 192 . ? 1_555 ? 41 AC6 3 ARG C 42 ? ARG C 23 . ? 2_565 ? 42 AC6 3 ASN D 85 ? ASN D 66 . ? 1_555 ? 43 AC6 3 SER D 87 ? SER D 68 . ? 1_555 ? # _database_PDB_matrix.entry_id 4UM1 _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 4UM1 _atom_sites.fract_transf_matrix[1][1] 0.012932 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.008123 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007846 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . LEU A 1 20 ? -11.161 63.784 -4.333 1.00 45.45 ? 1 LEU A N 1 ATOM 2 C CA . LEU A 1 20 ? -10.887 62.752 -5.333 1.00 39.77 ? 1 LEU A CA 1 ATOM 3 C C . LEU A 1 20 ? -12.056 61.794 -5.504 1.00 41.63 ? 1 LEU A C 1 ATOM 4 O O . LEU A 1 20 ? -12.591 61.269 -4.526 1.00 46.41 ? 1 LEU A O 1 ATOM 5 C CB . LEU A 1 20 ? -9.663 61.931 -4.943 1.00 42.64 ? 1 LEU A CB 1 ATOM 6 C CG . LEU A 1 20 ? -8.292 62.574 -5.103 1.00 42.18 ? 1 LEU A CG 1 ATOM 7 C CD1 . LEU A 1 20 ? -7.210 61.538 -4.832 1.00 36.99 ? 1 LEU A CD1 1 ATOM 8 C CD2 . LEU A 1 20 ? -8.147 63.154 -6.489 1.00 31.25 ? 1 LEU A CD2 1 ATOM 9 N N . ASP A 1 21 ? -12.454 61.564 -6.747 1.00 40.38 ? 2 ASP A N 1 ATOM 10 C CA . ASP A 1 21 ? -13.413 60.505 -7.041 1.00 38.89 ? 2 ASP A CA 1 ATOM 11 C C . ASP A 1 21 ? -12.700 59.383 -7.813 1.00 40.04 ? 2 ASP A C 1 ATOM 12 O O . ASP A 1 21 ? -11.514 59.511 -8.146 1.00 37.12 ? 2 ASP A O 1 ATOM 13 C CB . ASP A 1 21 ? -14.630 61.049 -7.810 1.00 39.45 ? 2 ASP A CB 1 ATOM 14 C CG . ASP A 1 21 ? -14.243 62.012 -8.932 1.00 56.31 ? 2 ASP A CG 1 ATOM 15 O OD1 . ASP A 1 21 ? -13.211 61.775 -9.604 1.00 57.52 ? 2 ASP A OD1 1 ATOM 16 O OD2 . ASP A 1 21 ? -14.973 63.010 -9.146 1.00 67.19 ? 2 ASP A OD2 1 ATOM 17 N N . ARG A 1 22 ? -13.405 58.288 -8.089 1.00 33.82 ? 3 ARG A N 1 ATOM 18 C CA . ARG A 1 22 ? -12.800 57.188 -8.818 1.00 27.89 ? 3 ARG A CA 1 ATOM 19 C C . ARG A 1 22 ? -12.213 57.626 -10.151 1.00 29.03 ? 3 ARG A C 1 ATOM 20 O O . ARG A 1 22 ? -11.134 57.160 -10.534 1.00 35.36 ? 3 ARG A O 1 ATOM 21 C CB . ARG A 1 22 ? -13.798 56.065 -9.045 1.00 29.31 ? 3 ARG A CB 1 ATOM 22 C CG . ARG A 1 22 ? -14.027 55.198 -7.855 1.00 26.28 ? 3 ARG A CG 1 ATOM 23 C CD . ARG A 1 22 ? -15.027 54.106 -8.188 1.00 33.18 ? 3 ARG A CD 1 ATOM 24 N NE . ARG A 1 22 ? -15.232 53.242 -7.035 1.00 45.67 ? 3 ARG A NE 1 ATOM 25 C CZ . ARG A 1 22 ? -16.056 53.535 -6.033 1.00 58.72 ? 3 ARG A CZ 1 ATOM 26 N NH1 . ARG A 1 22 ? -16.766 54.663 -6.057 1.00 50.45 ? 3 ARG A NH1 1 ATOM 27 N NH2 . ARG A 1 22 ? -16.169 52.696 -5.009 1.00 65.32 ? 3 ARG A NH2 1 ATOM 28 N N . ALA A 1 23 ? -12.916 58.514 -10.849 1.00 26.31 ? 4 ALA A N 1 ATOM 29 C CA . ALA A 1 23 ? -12.479 58.945 -12.169 1.00 27.99 ? 4 ALA A CA 1 ATOM 30 C C . ALA A 1 23 ? -11.098 59.589 -12.098 1.00 31.11 ? 4 ALA A C 1 ATOM 31 O O . ALA A 1 23 ? -10.217 59.295 -12.918 1.00 27.77 ? 4 ALA A O 1 ATOM 32 C CB . ALA A 1 23 ? -13.483 59.888 -12.767 1.00 36.90 ? 4 ALA A CB 1 ATOM 33 N N . ASP A 1 24 ? -10.914 60.447 -11.093 1.00 34.29 ? 5 ASP A N 1 ATOM 34 C CA . ASP A 1 24 ? -9.649 61.146 -10.855 1.00 26.61 ? 5 ASP A CA 1 ATOM 35 C C . ASP A 1 24 ? -8.487 60.198 -10.515 1.00 26.01 ? 5 ASP A C 1 ATOM 36 O O . ASP A 1 24 ? -7.392 60.324 -11.075 1.00 24.86 ? 5 ASP A O 1 ATOM 37 C CB . ASP A 1 24 ? -9.841 62.188 -9.753 1.00 34.51 ? 5 ASP A CB 1 ATOM 38 C CG . ASP A 1 24 ? -10.684 63.384 -10.209 1.00 54.21 ? 5 ASP A CG 1 ATOM 39 O OD1 . ASP A 1 24 ? -10.604 63.733 -11.418 1.00 58.36 ? 5 ASP A OD1 1 ATOM 40 O OD2 . ASP A 1 24 ? -11.412 63.971 -9.352 1.00 52.38 ? 5 ASP A OD2 1 ATOM 41 N N . ILE A 1 25 ? -8.742 59.241 -9.618 1.00 27.52 ? 6 ILE A N 1 ATOM 42 C CA . ILE A 1 25 ? -7.751 58.228 -9.225 1.00 24.10 ? 6 ILE A CA 1 ATOM 43 C C . ILE A 1 25 ? -7.265 57.370 -10.390 1.00 21.30 ? 6 ILE A C 1 ATOM 44 O O . ILE A 1 25 ? -6.060 57.200 -10.607 1.00 19.28 ? 6 ILE A O 1 ATOM 45 C CB . ILE A 1 25 ? -8.292 57.297 -8.106 1.00 24.42 ? 6 ILE A CB 1 ATOM 46 C CG1 . ILE A 1 25 ? -8.568 58.102 -6.835 1.00 27.93 ? 6 ILE A CG1 1 ATOM 47 C CG2 . ILE A 1 25 ? -7.293 56.178 -7.789 1.00 20.62 ? 6 ILE A CG2 1 ATOM 48 C CD1 . ILE A 1 25 ? -9.345 57.339 -5.780 1.00 28.12 ? 6 ILE A CD1 1 ATOM 49 N N . LEU A 1 26 ? -8.215 56.827 -11.138 1.00 21.87 ? 7 LEU A N 1 ATOM 50 C CA . LEU A 1 26 ? -7.883 55.985 -12.274 1.00 20.57 ? 7 LEU A CA 1 ATOM 51 C C . LEU A 1 26 ? -7.142 56.781 -13.335 1.00 22.02 ? 7 LEU A C 1 ATOM 52 O O . LEU A 1 26 ? -6.256 56.254 -14.018 1.00 24.72 ? 7 LEU A O 1 ATOM 53 C CB . LEU A 1 26 ? -9.136 55.326 -12.837 1.00 18.93 ? 7 LEU A CB 1 ATOM 54 C CG . LEU A 1 26 ? -9.746 54.323 -11.853 1.00 20.01 ? 7 LEU A CG 1 ATOM 55 C CD1 . LEU A 1 26 ? -11.195 54.026 -12.201 1.00 21.42 ? 7 LEU A CD1 1 ATOM 56 C CD2 . LEU A 1 26 ? -8.931 53.024 -11.777 1.00 15.60 ? 7 LEU A CD2 1 ATOM 57 N N . TYR A 1 27 ? -7.487 58.059 -13.453 1.00 20.50 ? 8 TYR A N 1 ATOM 58 C CA . TYR A 1 27 ? -6.786 58.940 -14.376 1.00 20.36 ? 8 TYR A CA 1 ATOM 59 C C . TYR A 1 27 ? -5.332 59.089 -13.963 1.00 20.54 ? 8 TYR A C 1 ATOM 60 O O . TYR A 1 27 ? -4.441 58.843 -14.765 1.00 21.76 ? 8 TYR A O 1 ATOM 61 C CB . TYR A 1 27 ? -7.460 60.306 -14.442 1.00 23.98 ? 8 TYR A CB 1 ATOM 62 C CG . TYR A 1 27 ? -6.761 61.277 -15.359 1.00 26.92 ? 8 TYR A CG 1 ATOM 63 C CD1 . TYR A 1 27 ? -6.918 61.191 -16.736 1.00 31.90 ? 8 TYR A CD1 1 ATOM 64 C CD2 . TYR A 1 27 ? -5.950 62.293 -14.848 1.00 27.35 ? 8 TYR A CD2 1 ATOM 65 C CE1 . TYR A 1 27 ? -6.281 62.088 -17.589 1.00 35.06 ? 8 TYR A CE1 1 ATOM 66 C CE2 . TYR A 1 27 ? -5.319 63.203 -15.687 1.00 31.88 ? 8 TYR A CE2 1 ATOM 67 C CZ . TYR A 1 27 ? -5.486 63.089 -17.058 1.00 40.74 ? 8 TYR A CZ 1 ATOM 68 O OH . TYR A 1 27 ? -4.859 63.979 -17.901 1.00 58.29 ? 8 TYR A OH 1 ATOM 69 N N . ASN A 1 28 ? -5.096 59.487 -12.715 1.00 18.02 ? 9 ASN A N 1 ATOM 70 C CA . ASN A 1 28 ? -3.733 59.600 -12.211 1.00 21.20 ? 9 ASN A CA 1 ATOM 71 C C . ASN A 1 28 ? -2.926 58.320 -12.371 1.00 21.47 ? 9 ASN A C 1 ATOM 72 O O . ASN A 1 28 ? -1.755 58.370 -12.750 1.00 25.36 ? 9 ASN A O 1 ATOM 73 C CB . ASN A 1 28 ? -3.717 60.048 -10.749 1.00 24.36 ? 9 ASN A CB 1 ATOM 74 C CG . ASN A 1 28 ? -4.327 61.423 -10.559 1.00 22.42 ? 9 ASN A CG 1 ATOM 75 O OD1 . ASN A 1 28 ? -4.349 62.239 -11.480 1.00 22.43 ? 9 ASN A OD1 1 ATOM 76 N ND2 . ASN A 1 28 ? -4.840 61.681 -9.356 1.00 20.69 ? 9 ASN A ND2 1 ATOM 77 N N . ILE A 1 29 ? -3.559 57.180 -12.095 1.00 23.18 ? 10 ILE A N 1 ATOM 78 C CA . ILE A 1 29 ? -2.895 55.889 -12.233 1.00 18.26 ? 10 ILE A CA 1 ATOM 79 C C . ILE A 1 29 ? -2.497 55.609 -13.670 1.00 22.02 ? 10 ILE A C 1 ATOM 80 O O . ILE A 1 29 ? -1.375 55.200 -13.936 1.00 26.76 ? 10 ILE A O 1 ATOM 81 C CB . ILE A 1 29 ? -3.720 54.735 -11.658 1.00 16.84 ? 10 ILE A CB 1 ATOM 82 C CG1 . ILE A 1 29 ? -3.790 54.883 -10.130 1.00 16.31 ? 10 ILE A CG1 1 ATOM 83 C CG2 . ILE A 1 29 ? -3.096 53.389 -12.056 1.00 15.57 ? 10 ILE A CG2 1 ATOM 84 C CD1 . ILE A 1 29 ? -4.514 53.764 -9.394 1.00 14.37 ? 10 ILE A CD1 1 ATOM 85 N N . ARG A 1 30 ? -3.398 55.869 -14.606 1.00 19.03 ? 11 ARG A N 1 ATOM 86 C CA . ARG A 1 30 ? -3.070 55.661 -16.003 1.00 19.30 ? 11 ARG A CA 1 ATOM 87 C C . ARG A 1 30 ? -1.904 56.523 -16.499 1.00 24.94 ? 11 ARG A C 1 ATOM 88 O O . ARG A 1 30 ? -1.148 56.097 -17.362 1.00 30.90 ? 11 ARG A O 1 ATOM 89 C CB . ARG A 1 30 ? -4.293 55.892 -16.871 1.00 28.96 ? 11 ARG A CB 1 ATOM 90 C CG . ARG A 1 30 ? -4.393 54.912 -17.992 1.00 50.83 ? 11 ARG A CG 1 ATOM 91 C CD . ARG A 1 30 ? -4.946 55.535 -19.259 1.00 60.55 ? 11 ARG A CD 1 ATOM 92 N NE . ARG A 1 30 ? -4.608 54.693 -20.410 1.00 89.27 ? 11 ARG A NE 1 ATOM 93 C CZ . ARG A 1 30 ? -4.935 54.956 -21.673 1.00 77.76 ? 11 ARG A CZ 1 ATOM 94 N NH1 . ARG A 1 30 ? -5.626 56.049 -21.976 1.00 66.58 ? 11 ARG A NH1 1 ATOM 95 N NH2 . ARG A 1 30 ? -4.567 54.118 -22.635 1.00 76.10 ? 11 ARG A NH2 1 ATOM 96 N N . GLN A 1 31 ? -1.752 57.726 -15.947 1.00 30.73 ? 12 GLN A N 1 ATOM 97 C CA . GLN A 1 31 ? -0.702 58.663 -16.374 1.00 24.91 ? 12 GLN A CA 1 ATOM 98 C C . GLN A 1 31 ? 0.679 58.469 -15.730 1.00 26.55 ? 12 GLN A C 1 ATOM 99 O O . GLN A 1 31 ? 1.671 58.915 -16.286 1.00 35.65 ? 12 GLN A O 1 ATOM 100 C CB . GLN A 1 31 ? -1.142 60.099 -16.129 1.00 24.06 ? 12 GLN A CB 1 ATOM 101 C CG . GLN A 1 31 ? -2.453 60.504 -16.797 1.00 31.66 ? 12 GLN A CG 1 ATOM 102 C CD . GLN A 1 31 ? -2.347 60.564 -18.304 1.00 41.90 ? 12 GLN A CD 1 ATOM 103 O OE1 . GLN A 1 31 ? -1.244 60.525 -18.865 1.00 46.70 ? 12 GLN A OE1 1 ATOM 104 N NE2 . GLN A 1 31 ? -3.497 60.647 -18.975 1.00 37.59 ? 12 GLN A NE2 1 ATOM 105 N N . THR A 1 32 ? 0.754 57.816 -14.574 1.00 20.36 ? 13 THR A N 1 ATOM 106 C CA . THR A 1 32 ? 1.976 57.876 -13.787 1.00 25.19 ? 13 THR A CA 1 ATOM 107 C C . THR A 1 32 ? 2.476 56.532 -13.296 1.00 36.98 ? 13 THR A C 1 ATOM 108 O O . THR A 1 32 ? 3.414 56.465 -12.481 1.00 41.39 ? 13 THR A O 1 ATOM 109 C CB . THR A 1 32 ? 1.775 58.772 -12.528 1.00 32.39 ? 13 THR A CB 1 ATOM 110 O OG1 . THR A 1 32 ? 0.745 58.224 -11.699 1.00 26.18 ? 13 THR A OG1 1 ATOM 111 C CG2 . THR A 1 32 ? 1.388 60.202 -12.907 1.00 31.93 ? 13 THR A CG2 1 ATOM 112 N N . SER A 1 33 ? 1.786 55.498 -13.723 1.00 44.86 ? 14 SER A N 1 ATOM 113 C CA . SER A 1 33 ? 1.945 54.163 -13.186 1.00 40.28 ? 14 SER A CA 1 ATOM 114 C C . SER A 1 33 ? 3.265 53.483 -13.427 1.00 44.77 ? 14 SER A C 1 ATOM 115 O O . SER A 1 33 ? 3.761 52.835 -12.527 1.00 37.78 ? 14 SER A O 1 ATOM 116 C CB . SER A 1 33 ? 0.798 53.283 -13.617 1.00 31.49 ? 14 SER A CB 1 ATOM 117 O OG . SER A 1 33 ? 1.001 51.986 -13.198 1.00 33.90 ? 14 SER A OG 1 ATOM 118 N N . ARG A 1 34 ? 3.853 53.631 -14.610 1.00 35.32 ? 15 ARG A N 1 ATOM 119 C CA . ARG A 1 34 ? 5.093 52.920 -14.876 1.00 30.81 ? 15 ARG A CA 1 ATOM 120 C C . ARG A 1 34 ? 5.048 51.407 -14.750 1.00 24.52 ? 15 ARG A C 1 ATOM 121 O O . ARG A 1 34 ? 5.605 50.853 -13.890 1.00 25.00 ? 15 ARG A O 1 ATOM 122 C CB . ARG A 1 34 ? 6.207 53.477 -14.002 1.00 37.47 ? 15 ARG A CB 1 ATOM 123 C CG . ARG A 1 34 ? 6.588 54.891 -14.318 1.00 39.26 ? 15 ARG A CG 1 ATOM 124 C CD . ARG A 1 34 ? 6.719 55.102 -15.807 1.00 45.42 ? 15 ARG A CD 1 ATOM 125 N NE . ARG A 1 34 ? 7.969 54.593 -16.354 1.00 49.21 ? 15 ARG A NE 1 ATOM 126 C CZ . ARG A 1 34 ? 9.156 55.157 -16.219 1.00 39.80 ? 15 ARG A CZ 1 ATOM 127 N NH1 . ARG A 1 34 ? 9.300 56.279 -15.556 1.00 31.65 ? 15 ARG A NH1 1 ATOM 128 N NH2 . ARG A 1 34 ? 10.193 54.599 -16.766 1.00 26.05 ? 15 ARG A NH2 1 ATOM 129 N N . PRO A 1 35 ? 4.316 50.748 -15.709 1.00 25.13 ? 16 PRO A N 1 ATOM 130 C CA . PRO A 1 35 ? 4.248 49.285 -15.607 1.00 24.79 ? 16 PRO A CA 1 ATOM 131 C C . PRO A 1 35 ? 5.523 48.478 -15.861 1.00 24.40 ? 16 PRO A C 1 ATOM 132 O O . PRO A 1 35 ? 5.549 47.307 -15.663 1.00 18.88 ? 16 PRO A O 1 ATOM 133 C CB . PRO A 1 35 ? 3.263 48.924 -16.693 1.00 22.53 ? 16 PRO A CB 1 ATOM 134 C CG . PRO A 1 35 ? 2.480 50.102 -16.900 1.00 21.34 ? 16 PRO A CG 1 ATOM 135 C CD . PRO A 1 35 ? 3.507 51.107 -16.944 1.00 26.04 ? 16 PRO A CD 1 ATOM 136 N N . ASP A 1 36 ? 6.533 49.100 -16.420 1.00 30.71 ? 17 ASP A N 1 ATOM 137 C CA . ASP A 1 36 ? 7.800 48.466 -16.681 1.00 28.04 ? 17 ASP A CA 1 ATOM 138 C C . ASP A 1 36 ? 8.766 48.523 -15.522 1.00 19.69 ? 17 ASP A C 1 ATOM 139 O O . ASP A 1 36 ? 9.765 47.908 -15.541 1.00 23.91 ? 17 ASP A O 1 ATOM 140 C CB . ASP A 1 36 ? 8.395 49.065 -17.953 1.00 22.32 ? 17 ASP A CB 1 ATOM 141 C CG . ASP A 1 36 ? 8.250 50.551 -18.020 1.00 44.24 ? 17 ASP A CG 1 ATOM 142 O OD1 . ASP A 1 36 ? 7.259 51.084 -17.533 1.00 39.25 ? 17 ASP A OD1 1 ATOM 143 O OD2 . ASP A 1 36 ? 9.133 51.207 -18.591 1.00 50.27 ? 17 ASP A OD2 1 ATOM 144 N N . VAL A 1 37 ? 8.413 49.254 -14.495 1.00 21.65 ? 18 VAL A N 1 ATOM 145 C CA . VAL A 1 37 ? 9.322 49.534 -13.376 1.00 22.34 ? 18 VAL A CA 1 ATOM 146 C C . VAL A 1 37 ? 8.935 48.834 -12.072 1.00 20.93 ? 18 VAL A C 1 ATOM 147 O O . VAL A 1 37 ? 7.909 49.151 -11.457 1.00 17.83 ? 18 VAL A O 1 ATOM 148 C CB . VAL A 1 37 ? 9.381 51.038 -13.052 1.00 18.53 ? 18 VAL A CB 1 ATOM 149 C CG1 . VAL A 1 37 ? 10.279 51.266 -11.848 1.00 10.96 ? 18 VAL A CG1 1 ATOM 150 C CG2 . VAL A 1 37 ? 9.848 51.826 -14.252 1.00 21.77 ? 18 VAL A CG2 1 ATOM 151 N N . ILE A 1 38 ? 9.778 47.902 -11.646 1.00 21.10 ? 19 ILE A N 1 ATOM 152 C CA . ILE A 1 38 ? 9.583 47.192 -10.381 1.00 24.13 ? 19 ILE A CA 1 ATOM 153 C C . ILE A 1 38 ? 9.617 48.162 -9.172 1.00 22.58 ? 19 ILE A C 1 ATOM 154 O O . ILE A 1 38 ? 10.558 48.943 -9.022 1.00 28.21 ? 19 ILE A O 1 ATOM 155 C CB . ILE A 1 38 ? 10.621 46.032 -10.252 1.00 20.38 ? 19 ILE A CB 1 ATOM 156 C CG1 . ILE A 1 38 ? 10.371 45.193 -9.002 1.00 22.57 ? 19 ILE A CG1 1 ATOM 157 C CG2 . ILE A 1 38 ? 12.051 46.566 -10.288 1.00 16.79 ? 19 ILE A CG2 1 ATOM 158 C CD1 . ILE A 1 38 ? 11.231 43.934 -8.949 1.00 26.34 ? 19 ILE A CD1 1 ATOM 159 N N . PRO A 1 39 ? 8.571 48.123 -8.316 1.00 23.71 ? 20 PRO A N 1 ATOM 160 C CA . PRO A 1 39 ? 8.429 49.090 -7.215 1.00 22.12 ? 20 PRO A CA 1 ATOM 161 C C . PRO A 1 39 ? 9.265 48.729 -5.984 1.00 27.06 ? 20 PRO A C 1 ATOM 162 O O . PRO A 1 39 ? 8.708 48.520 -4.892 1.00 25.99 ? 20 PRO A O 1 ATOM 163 C CB . PRO A 1 39 ? 6.924 49.034 -6.890 1.00 19.48 ? 20 PRO A CB 1 ATOM 164 C CG . PRO A 1 39 ? 6.526 47.615 -7.214 1.00 20.55 ? 20 PRO A CG 1 ATOM 165 C CD . PRO A 1 39 ? 7.426 47.183 -8.380 1.00 25.06 ? 20 PRO A CD 1 ATOM 166 N N . THR A 1 40 ? 10.584 48.665 -6.163 1.00 29.37 ? 21 THR A N 1 ATOM 167 C CA . THR A 1 40 ? 11.495 48.400 -5.050 1.00 37.64 ? 21 THR A CA 1 ATOM 168 C C . THR A 1 40 ? 11.544 49.602 -4.123 1.00 46.16 ? 21 THR A C 1 ATOM 169 O O . THR A 1 40 ? 11.327 50.735 -4.556 1.00 47.60 ? 21 THR A O 1 ATOM 170 C CB . THR A 1 40 ? 12.922 48.083 -5.532 1.00 36.95 ? 21 THR A CB 1 ATOM 171 O OG1 . THR A 1 40 ? 13.355 49.121 -6.414 1.00 44.23 ? 21 THR A OG1 1 ATOM 172 C CG2 . THR A 1 40 ? 12.971 46.749 -6.271 1.00 34.04 ? 21 THR A CG2 1 ATOM 173 N N . GLN A 1 41 ? 11.821 49.342 -2.848 1.00 53.99 ? 22 GLN A N 1 ATOM 174 C CA . GLN A 1 41 ? 11.925 50.397 -1.847 1.00 63.28 ? 22 GLN A CA 1 ATOM 175 C C . GLN A 1 41 ? 13.279 50.339 -1.153 1.00 67.64 ? 22 GLN A C 1 ATOM 176 O O . GLN A 1 41 ? 13.423 49.665 -0.135 1.00 67.67 ? 22 GLN A O 1 ATOM 177 C CB . GLN A 1 41 ? 10.820 50.261 -0.795 1.00 62.88 ? 22 GLN A CB 1 ATOM 178 C CG . GLN A 1 41 ? 9.506 50.962 -1.118 1.00 67.58 ? 22 GLN A CG 1 ATOM 179 C CD . GLN A 1 41 ? 8.495 50.859 0.029 1.00 80.43 ? 22 GLN A CD 1 ATOM 180 O OE1 . GLN A 1 41 ? 8.139 49.753 0.472 1.00 60.61 ? 22 GLN A OE1 1 ATOM 181 N NE2 . GLN A 1 41 ? 8.037 52.018 0.525 1.00 79.48 ? 22 GLN A NE2 1 ATOM 182 N N . ARG A 1 42 ? 14.199 51.143 -1.642 1.00 74.48 ? 23 ARG A N 1 ATOM 183 C CA . ARG A 1 42 ? 15.489 51.277 -1.033 1.00 75.51 ? 23 ARG A CA 1 ATOM 184 C C . ARG A 1 42 ? 16.187 49.969 -1.102 1.00 74.10 ? 23 ARG A C 1 ATOM 185 O O . ARG A 1 42 ? 16.874 49.589 -0.190 1.00 80.85 ? 23 ARG A O 1 ATOM 186 C CB . ARG A 1 42 ? 15.349 51.738 0.410 1.00 82.26 ? 23 ARG A CB 1 ATOM 187 C CG . ARG A 1 42 ? 14.526 53.009 0.590 1.00 81.59 ? 23 ARG A CG 1 ATOM 188 C CD . ARG A 1 42 ? 14.705 53.594 1.981 1.00 89.03 ? 23 ARG A CD 1 ATOM 189 N NE . ARG A 1 42 ? 13.437 53.974 2.589 1.00 91.17 ? 23 ARG A NE 1 ATOM 190 C CZ . ARG A 1 42 ? 13.209 53.984 3.895 1.00 89.64 ? 23 ARG A CZ 1 ATOM 191 N NH1 . ARG A 1 42 ? 14.159 53.640 4.748 1.00 90.11 ? 23 ARG A NH1 1 ATOM 192 N NH2 . ARG A 1 42 ? 12.026 54.326 4.350 1.00 92.39 ? 23 ARG A NH2 1 ATOM 193 N N . ASP A 1 43 ? 15.987 49.274 -2.205 1.00 70.38 ? 24 ASP A N 1 ATOM 194 C CA . ASP A 1 43 ? 16.831 48.155 -2.583 1.00 75.36 ? 24 ASP A CA 1 ATOM 195 C C . ASP A 1 43 ? 16.565 46.897 -1.781 1.00 65.76 ? 24 ASP A C 1 ATOM 196 O O . ASP A 1 43 ? 17.364 45.973 -1.757 1.00 61.39 ? 24 ASP A O 1 ATOM 197 C CB . ASP A 1 43 ? 18.306 48.552 -2.506 1.00 93.72 ? 24 ASP A CB 1 ATOM 198 C CG . ASP A 1 43 ? 18.755 49.425 -3.686 1.00 104.83 ? 24 ASP A CG 1 ATOM 199 O OD1 . ASP A 1 43 ? 18.336 49.159 -4.829 1.00 98.44 ? 24 ASP A OD1 1 ATOM 200 O OD2 . ASP A 1 43 ? 19.546 50.373 -3.478 1.00 107.05 ? 24 ASP A OD2 1 ATOM 201 N N . ARG A 1 44 ? 15.439 46.904 -1.100 1.00 56.98 ? 25 ARG A N 1 ATOM 202 C CA . ARG A 1 44 ? 14.819 45.737 -0.561 1.00 52.02 ? 25 ARG A CA 1 ATOM 203 C C . ARG A 1 44 ? 14.016 45.101 -1.667 1.00 52.37 ? 25 ARG A C 1 ATOM 204 O O . ARG A 1 44 ? 13.655 45.758 -2.610 1.00 50.47 ? 25 ARG A O 1 ATOM 205 C CB . ARG A 1 44 ? 13.912 46.165 0.563 1.00 55.81 ? 25 ARG A CB 1 ATOM 206 C CG . ARG A 1 44 ? 14.631 47.033 1.569 1.00 74.32 ? 25 ARG A CG 1 ATOM 207 C CD . ARG A 1 44 ? 13.774 47.275 2.800 1.00 88.38 ? 25 ARG A CD 1 ATOM 208 N NE . ARG A 1 44 ? 14.527 47.877 3.885 1.00 98.29 ? 25 ARG A NE 1 ATOM 209 C CZ . ARG A 1 44 ? 14.452 49.152 4.223 1.00 95.07 ? 25 ARG A CZ 1 ATOM 210 N NH1 . ARG A 1 44 ? 13.645 49.956 3.552 1.00 94.60 ? 25 ARG A NH1 1 ATOM 211 N NH2 . ARG A 1 44 ? 15.181 49.618 5.226 1.00 86.79 ? 25 ARG A NH2 1 ATOM 212 N N . PRO A 1 45 ? 13.749 43.815 -1.554 1.00 39.23 ? 26 PRO A N 1 ATOM 213 C CA . PRO A 1 45 ? 12.916 43.103 -2.527 1.00 26.99 ? 26 PRO A CA 1 ATOM 214 C C . PRO A 1 45 ? 11.467 43.556 -2.410 1.00 29.06 ? 26 PRO A C 1 ATOM 215 O O . PRO A 1 45 ? 11.061 44.060 -1.364 1.00 34.26 ? 26 PRO A O 1 ATOM 216 C CB . PRO A 1 45 ? 13.029 41.644 -2.084 1.00 27.82 ? 26 PRO A CB 1 ATOM 217 C CG . PRO A 1 45 ? 14.237 41.592 -1.214 1.00 36.58 ? 26 PRO A CG 1 ATOM 218 C CD . PRO A 1 45 ? 14.339 42.918 -0.548 1.00 36.24 ? 26 PRO A CD 1 ATOM 219 N N . VAL A 1 46 ? 10.698 43.407 -3.478 1.00 28.87 ? 27 VAL A N 1 ATOM 220 C CA . VAL A 1 46 ? 9.251 43.525 -3.374 1.00 25.42 ? 27 VAL A CA 1 ATOM 221 C C . VAL A 1 46 ? 8.763 42.215 -2.766 1.00 20.25 ? 27 VAL A C 1 ATOM 222 O O . VAL A 1 46 ? 9.095 41.136 -3.262 1.00 19.97 ? 27 VAL A O 1 ATOM 223 C CB . VAL A 1 46 ? 8.631 43.703 -4.758 1.00 20.91 ? 27 VAL A CB 1 ATOM 224 C CG1 . VAL A 1 46 ? 7.110 43.776 -4.661 1.00 18.39 ? 27 VAL A CG1 1 ATOM 225 C CG2 . VAL A 1 46 ? 9.217 44.925 -5.437 1.00 17.59 ? 27 VAL A CG2 1 ATOM 226 N N . ALA A 1 47 ? 8.012 42.285 -1.677 1.00 20.46 ? 28 ALA A N 1 ATOM 227 C CA . ALA A 1 47 ? 7.498 41.045 -1.087 1.00 22.70 ? 28 ALA A CA 1 ATOM 228 C C . ALA A 1 47 ? 6.189 40.638 -1.757 1.00 24.85 ? 28 ALA A C 1 ATOM 229 O O . ALA A 1 47 ? 5.149 41.264 -1.535 1.00 22.97 ? 28 ALA A O 1 ATOM 230 C CB . ALA A 1 47 ? 7.297 41.192 0.384 1.00 15.01 ? 28 ALA A CB 1 ATOM 231 N N . VAL A 1 48 ? 6.240 39.586 -2.567 1.00 22.40 ? 29 VAL A N 1 ATOM 232 C CA . VAL A 1 48 ? 5.042 39.043 -3.214 1.00 21.84 ? 29 VAL A CA 1 ATOM 233 C C . VAL A 1 48 ? 4.532 37.803 -2.458 1.00 22.21 ? 29 VAL A C 1 ATOM 234 O O . VAL A 1 48 ? 5.290 36.866 -2.196 1.00 23.07 ? 29 VAL A O 1 ATOM 235 C CB . VAL A 1 48 ? 5.362 38.645 -4.666 1.00 22.02 ? 29 VAL A CB 1 ATOM 236 C CG1 . VAL A 1 48 ? 4.126 38.111 -5.382 1.00 14.09 ? 29 VAL A CG1 1 ATOM 237 C CG2 . VAL A 1 48 ? 6.004 39.816 -5.409 1.00 13.63 ? 29 VAL A CG2 1 ATOM 238 N N . SER A 1 49 ? 3.253 37.799 -2.110 1.00 19.25 ? 30 SER A N 1 ATOM 239 C CA . SER A 1 49 ? 2.635 36.618 -1.518 1.00 18.93 ? 30 SER A CA 1 ATOM 240 C C . SER A 1 49 ? 1.850 35.874 -2.582 1.00 26.99 ? 30 SER A C 1 ATOM 241 O O . SER A 1 49 ? 1.120 36.495 -3.390 1.00 23.90 ? 30 SER A O 1 ATOM 242 C CB . SER A 1 49 ? 1.676 37.004 -0.408 1.00 20.20 ? 30 SER A CB 1 ATOM 243 O OG . SER A 1 49 ? 2.241 38.022 0.368 1.00 42.57 ? 30 SER A OG 1 ATOM 244 N N . VAL A 1 50 ? 1.981 34.547 -2.568 1.00 24.50 ? 31 VAL A N 1 ATOM 245 C CA . VAL A 1 50 ? 1.286 33.699 -3.525 1.00 23.76 ? 31 VAL A CA 1 ATOM 246 C C . VAL A 1 50 ? 0.471 32.627 -2.827 1.00 30.27 ? 31 VAL A C 1 ATOM 247 O O . VAL A 1 50 ? 0.961 31.971 -1.912 1.00 38.06 ? 31 VAL A O 1 ATOM 248 C CB . VAL A 1 50 ? 2.258 33.025 -4.464 1.00 17.81 ? 31 VAL A CB 1 ATOM 249 C CG1 . VAL A 1 50 ? 1.501 32.204 -5.481 1.00 19.24 ? 31 VAL A CG1 1 ATOM 250 C CG2 . VAL A 1 50 ? 3.109 34.065 -5.146 1.00 17.74 ? 31 VAL A CG2 1 ATOM 251 N N . SER A 1 51 ? -0.773 32.450 -3.262 1.00 28.75 ? 32 SER A N 1 ATOM 252 C CA . SER A 1 51 ? -1.638 31.438 -2.681 1.00 26.59 ? 32 SER A CA 1 ATOM 253 C C . SER A 1 51 ? -2.496 30.778 -3.761 1.00 23.87 ? 32 SER A C 1 ATOM 254 O O . SER A 1 51 ? -3.175 31.480 -4.504 1.00 28.26 ? 32 SER A O 1 ATOM 255 C CB . SER A 1 51 ? -2.522 32.079 -1.614 1.00 24.62 ? 32 SER A CB 1 ATOM 256 O OG . SER A 1 51 ? -3.329 31.097 -0.991 1.00 43.64 ? 32 SER A OG 1 ATOM 257 N N . LEU A 1 52 ? -2.465 29.445 -3.871 1.00 21.85 ? 33 LEU A N 1 ATOM 258 C CA . LEU A 1 52 ? -3.345 28.759 -4.836 1.00 18.20 ? 33 LEU A CA 1 ATOM 259 C C . LEU A 1 52 ? -4.615 28.230 -4.169 1.00 23.45 ? 33 LEU A C 1 ATOM 260 O O . LEU A 1 52 ? -4.547 27.544 -3.158 1.00 34.33 ? 33 LEU A O 1 ATOM 261 C CB . LEU A 1 52 ? -2.629 27.611 -5.541 1.00 13.57 ? 33 LEU A CB 1 ATOM 262 C CG . LEU A 1 52 ? -1.260 27.956 -6.128 1.00 19.46 ? 33 LEU A CG 1 ATOM 263 C CD1 . LEU A 1 52 ? -0.720 26.850 -7.013 1.00 15.96 ? 33 LEU A CD1 1 ATOM 264 C CD2 . LEU A 1 52 ? -1.309 29.277 -6.896 1.00 19.96 ? 33 LEU A CD2 1 ATOM 265 N N . LYS A 1 53 ? -5.776 28.557 -4.725 1.00 26.85 ? 34 LYS A N 1 ATOM 266 C CA . LYS A 1 53 ? -7.036 27.965 -4.280 1.00 24.47 ? 34 LYS A CA 1 ATOM 267 C C . LYS A 1 53 ? -7.482 27.010 -5.367 1.00 23.41 ? 34 LYS A C 1 ATOM 268 O O . LYS A 1 53 ? -7.778 27.449 -6.483 1.00 21.05 ? 34 LYS A O 1 ATOM 269 C CB . LYS A 1 53 ? -8.105 29.040 -4.083 1.00 21.51 ? 34 LYS A CB 1 ATOM 270 C CG . LYS A 1 53 ? -7.600 30.306 -3.406 1.00 30.21 ? 34 LYS A CG 1 ATOM 271 C CD . LYS A 1 53 ? -7.289 30.113 -1.927 1.00 39.79 ? 34 LYS A CD 1 ATOM 272 C CE . LYS A 1 53 ? -6.772 31.420 -1.290 1.00 31.16 ? 34 LYS A CE 1 ATOM 273 N NZ . LYS A 1 53 ? -6.450 31.192 0.163 1.00 61.59 ? 34 LYS A NZ 1 ATOM 274 N N . PHE A 1 54 ? -7.519 25.713 -5.064 1.00 21.41 ? 35 PHE A N 1 ATOM 275 C CA . PHE A 1 54 ? -7.891 24.747 -6.094 1.00 22.33 ? 35 PHE A CA 1 ATOM 276 C C . PHE A 1 54 ? -9.386 24.709 -6.341 1.00 20.96 ? 35 PHE A C 1 ATOM 277 O O . PHE A 1 54 ? -10.182 24.687 -5.408 1.00 27.71 ? 35 PHE A O 1 ATOM 278 C CB . PHE A 1 54 ? -7.324 23.368 -5.783 1.00 21.83 ? 35 PHE A CB 1 ATOM 279 C CG . PHE A 1 54 ? -5.836 23.346 -5.791 1.00 21.11 ? 35 PHE A CG 1 ATOM 280 C CD1 . PHE A 1 54 ? -5.147 23.210 -6.983 1.00 23.22 ? 35 PHE A CD1 1 ATOM 281 C CD2 . PHE A 1 54 ? -5.118 23.533 -4.617 1.00 21.25 ? 35 PHE A CD2 1 ATOM 282 C CE1 . PHE A 1 54 ? -3.758 23.225 -7.005 1.00 20.23 ? 35 PHE A CE1 1 ATOM 283 C CE2 . PHE A 1 54 ? -3.735 23.550 -4.626 1.00 15.20 ? 35 PHE A CE2 1 ATOM 284 C CZ . PHE A 1 54 ? -3.059 23.396 -5.820 1.00 18.91 ? 35 PHE A CZ 1 ATOM 285 N N . ILE A 1 55 ? -9.757 24.729 -7.612 1.00 20.18 ? 36 ILE A N 1 ATOM 286 C CA . ILE A 1 55 ? -11.166 24.737 -7.977 1.00 28.61 ? 36 ILE A CA 1 ATOM 287 C C . ILE A 1 55 ? -11.588 23.398 -8.596 1.00 25.43 ? 36 ILE A C 1 ATOM 288 O O . ILE A 1 55 ? -12.692 22.910 -8.345 1.00 25.20 ? 36 ILE A O 1 ATOM 289 C CB . ILE A 1 55 ? -11.513 25.931 -8.932 1.00 23.66 ? 36 ILE A CB 1 ATOM 290 C CG1 . ILE A 1 55 ? -10.929 27.252 -8.396 1.00 19.45 ? 36 ILE A CG1 1 ATOM 291 C CG2 . ILE A 1 55 ? -13.025 26.025 -9.152 1.00 13.11 ? 36 ILE A CG2 1 ATOM 292 C CD1 . ILE A 1 55 ? -11.436 27.654 -7.009 1.00 18.21 ? 36 ILE A CD1 1 ATOM 293 N N . ASN A 1 56 ? -10.707 22.807 -9.402 1.00 22.02 ? 37 ASN A N 1 ATOM 294 C CA . ASN A 1 56 ? -11.048 21.579 -10.097 1.00 20.64 ? 37 ASN A CA 1 ATOM 295 C C . ASN A 1 56 ? -9.830 20.783 -10.514 1.00 24.52 ? 37 ASN A C 1 ATOM 296 O O . ASN A 1 56 ? -8.756 21.342 -10.691 1.00 25.67 ? 37 ASN A O 1 ATOM 297 C CB . ASN A 1 56 ? -11.905 21.894 -11.333 1.00 23.39 ? 37 ASN A CB 1 ATOM 298 C CG . ASN A 1 56 ? -13.044 20.901 -11.525 1.00 28.99 ? 37 ASN A CG 1 ATOM 299 O OD1 . ASN A 1 56 ? -12.862 19.673 -11.441 1.00 22.99 ? 37 ASN A OD1 1 ATOM 300 N ND2 . ASN A 1 56 ? -14.235 21.435 -11.776 1.00 33.51 ? 37 ASN A ND2 1 ATOM 301 N N . ILE A 1 57 ? -10.005 19.471 -10.670 1.00 31.30 ? 38 ILE A N 1 ATOM 302 C CA . ILE A 1 57 ? -8.973 18.618 -11.268 1.00 27.40 ? 38 ILE A CA 1 ATOM 303 C C . ILE A 1 57 ? -9.624 17.862 -12.416 1.00 27.63 ? 38 ILE A C 1 ATOM 304 O O . ILE A 1 57 ? -10.672 17.248 -12.231 1.00 33.65 ? 38 ILE A O 1 ATOM 305 C CB . ILE A 1 57 ? -8.344 17.673 -10.234 1.00 20.62 ? 38 ILE A CB 1 ATOM 306 C CG1 . ILE A 1 57 ? -7.618 18.511 -9.178 1.00 18.27 ? 38 ILE A CG1 1 ATOM 307 C CG2 . ILE A 1 57 ? -7.388 16.724 -10.912 1.00 17.92 ? 38 ILE A CG2 1 ATOM 308 C CD1 . ILE A 1 57 ? -7.098 17.760 -8.023 1.00 18.02 ? 38 ILE A CD1 1 ATOM 309 N N . LEU A 1 58 ? -9.038 17.939 -13.610 1.00 31.11 ? 39 LEU A N 1 ATOM 310 C CA . LEU A 1 58 ? -9.817 17.670 -14.816 1.00 33.65 ? 39 LEU A CA 1 ATOM 311 C C . LEU A 1 58 ? -9.392 16.470 -15.607 1.00 42.58 ? 39 LEU A C 1 ATOM 312 O O . LEU A 1 58 ? -10.226 15.629 -15.966 1.00 60.81 ? 39 LEU A O 1 ATOM 313 C CB . LEU A 1 58 ? -9.853 18.882 -15.743 1.00 34.04 ? 39 LEU A CB 1 ATOM 314 C CG . LEU A 1 58 ? -10.690 20.062 -15.256 1.00 33.70 ? 39 LEU A CG 1 ATOM 315 C CD1 . LEU A 1 58 ? -10.621 21.159 -16.276 1.00 39.59 ? 39 LEU A CD1 1 ATOM 316 C CD2 . LEU A 1 58 ? -12.132 19.654 -15.024 1.00 38.95 ? 39 LEU A CD2 1 ATOM 317 N N . GLU A 1 59 ? -8.113 16.389 -15.926 1.00 31.76 ? 40 GLU A N 1 ATOM 318 C CA . GLU A 1 59 ? -7.684 15.285 -16.774 1.00 34.82 ? 40 GLU A CA 1 ATOM 319 C C . GLU A 1 59 ? -6.407 14.704 -16.266 1.00 39.04 ? 40 GLU A C 1 ATOM 320 O O . GLU A 1 59 ? -5.325 15.270 -16.439 1.00 44.35 ? 40 GLU A O 1 ATOM 321 C CB . GLU A 1 59 ? -7.528 15.725 -18.218 1.00 38.04 ? 40 GLU A CB 1 ATOM 322 C CG . GLU A 1 59 ? -8.594 15.147 -19.112 1.00 54.22 ? 40 GLU A CG 1 ATOM 323 C CD . GLU A 1 59 ? -8.977 16.088 -20.237 1.00 65.72 ? 40 GLU A CD 1 ATOM 324 O OE1 . GLU A 1 59 ? -8.441 17.222 -20.262 1.00 70.71 ? 40 GLU A OE1 1 ATOM 325 O OE2 . GLU A 1 59 ? -9.812 15.694 -21.087 1.00 72.26 ? 40 GLU A OE2 1 ATOM 326 N N . VAL A 1 60 ? -6.531 13.562 -15.621 1.00 36.00 ? 41 VAL A N 1 ATOM 327 C CA . VAL A 1 60 ? -5.366 12.948 -15.041 1.00 32.64 ? 41 VAL A CA 1 ATOM 328 C C . VAL A 1 60 ? -4.920 11.804 -15.937 1.00 27.30 ? 41 VAL A C 1 ATOM 329 O O . VAL A 1 60 ? -5.738 11.077 -16.488 1.00 30.24 ? 41 VAL A O 1 ATOM 330 C CB . VAL A 1 60 ? -5.663 12.498 -13.613 1.00 34.37 ? 41 VAL A CB 1 ATOM 331 C CG1 . VAL A 1 60 ? -4.516 11.728 -13.067 1.00 34.65 ? 41 VAL A CG1 1 ATOM 332 C CG2 . VAL A 1 60 ? -5.934 13.712 -12.734 1.00 32.18 ? 41 VAL A CG2 1 ATOM 333 N N . ASN A 1 61 ? -3.616 11.692 -16.129 1.00 27.48 ? 42 ASN A N 1 ATOM 334 C CA . ASN A 1 61 ? -3.048 10.574 -16.857 1.00 26.36 ? 42 ASN A CA 1 ATOM 335 C C . ASN A 1 61 ? -1.880 9.985 -16.073 1.00 30.31 ? 42 ASN A C 1 ATOM 336 O O . ASN A 1 61 ? -0.796 10.587 -16.005 1.00 27.39 ? 42 ASN A O 1 ATOM 337 C CB . ASN A 1 61 ? -2.608 11.014 -18.255 1.00 26.55 ? 42 ASN A CB 1 ATOM 338 C CG . ASN A 1 61 ? -2.197 9.841 -19.147 1.00 34.52 ? 42 ASN A CG 1 ATOM 339 O OD1 . ASN A 1 61 ? -1.564 8.867 -18.691 1.00 33.09 ? 42 ASN A OD1 1 ATOM 340 N ND2 . ASN A 1 61 ? -2.566 9.926 -20.430 1.00 31.98 ? 42 ASN A ND2 1 ATOM 341 N N . GLU A 1 62 ? -2.115 8.808 -15.480 1.00 35.88 ? 43 GLU A N 1 ATOM 342 C CA . GLU A 1 62 ? -1.118 8.150 -14.627 1.00 31.63 ? 43 GLU A CA 1 ATOM 343 C C . GLU A 1 62 ? 0.009 7.615 -15.490 1.00 30.69 ? 43 GLU A C 1 ATOM 344 O O . GLU A 1 62 ? 1.154 7.538 -15.035 1.00 41.78 ? 43 GLU A O 1 ATOM 345 C CB . GLU A 1 62 ? -1.735 7.044 -13.750 1.00 31.91 ? 43 GLU A CB 1 ATOM 346 C CG . GLU A 1 62 ? -0.908 6.689 -12.477 1.00 44.14 ? 43 GLU A CG 1 ATOM 347 C CD . GLU A 1 62 ? -1.596 5.653 -11.546 1.00 52.25 ? 43 GLU A CD 1 ATOM 348 O OE1 . GLU A 1 62 ? -2.811 5.370 -11.728 1.00 48.61 ? 43 GLU A OE1 1 ATOM 349 O OE2 . GLU A 1 62 ? -0.913 5.127 -10.625 1.00 44.38 ? 43 GLU A OE2 1 ATOM 350 N N . ILE A 1 63 ? -0.305 7.286 -16.743 1.00 28.00 ? 44 ILE A N 1 ATOM 351 C CA . ILE A 1 63 ? 0.708 6.762 -17.662 1.00 32.50 ? 44 ILE A CA 1 ATOM 352 C C . ILE A 1 63 ? 1.767 7.803 -18.001 1.00 30.09 ? 44 ILE A C 1 ATOM 353 O O . ILE A 1 63 ? 2.965 7.503 -17.979 1.00 38.68 ? 44 ILE A O 1 ATOM 354 C CB . ILE A 1 63 ? 0.124 6.235 -19.012 1.00 36.89 ? 44 ILE A CB 1 ATOM 355 C CG1 . ILE A 1 63 ? -0.973 5.185 -18.798 1.00 28.25 ? 44 ILE A CG1 1 ATOM 356 C CG2 . ILE A 1 63 ? 1.254 5.695 -19.902 1.00 28.72 ? 44 ILE A CG2 1 ATOM 357 C CD1 . ILE A 1 63 ? -0.509 3.946 -18.114 1.00 26.81 ? 44 ILE A CD1 1 ATOM 358 N N . THR A 1 64 ? 1.325 9.016 -18.327 1.00 33.70 ? 45 THR A N 1 ATOM 359 C CA . THR A 1 64 ? 2.237 10.058 -18.815 1.00 31.01 ? 45 THR A CA 1 ATOM 360 C C . THR A 1 64 ? 2.612 11.041 -17.725 1.00 30.99 ? 45 THR A C 1 ATOM 361 O O . THR A 1 64 ? 3.417 11.938 -17.963 1.00 36.27 ? 45 THR A O 1 ATOM 362 C CB . THR A 1 64 ? 1.628 10.872 -19.963 1.00 22.74 ? 45 THR A CB 1 ATOM 363 O OG1 . THR A 1 64 ? 0.500 11.591 -19.468 1.00 28.02 ? 45 THR A OG1 1 ATOM 364 C CG2 . THR A 1 64 ? 1.179 9.983 -21.083 1.00 22.74 ? 45 THR A CG2 1 ATOM 365 N N . ASN A 1 65 ? 2.013 10.889 -16.546 1.00 28.69 ? 46 ASN A N 1 ATOM 366 C CA . ASN A 1 65 ? 2.277 11.797 -15.429 1.00 35.78 ? 46 ASN A CA 1 ATOM 367 C C . ASN A 1 65 ? 1.933 13.277 -15.709 1.00 32.37 ? 46 ASN A C 1 ATOM 368 O O . ASN A 1 65 ? 2.766 14.172 -15.549 1.00 29.36 ? 46 ASN A O 1 ATOM 369 C CB . ASN A 1 65 ? 3.728 11.654 -14.936 1.00 35.01 ? 46 ASN A CB 1 ATOM 370 C CG . ASN A 1 65 ? 3.876 10.622 -13.827 1.00 38.40 ? 46 ASN A CG 1 ATOM 371 O OD1 . ASN A 1 65 ? 2.909 10.280 -13.136 1.00 37.25 ? 46 ASN A OD1 1 ATOM 372 N ND2 . ASN A 1 65 ? 5.101 10.131 -13.640 1.00 35.44 ? 46 ASN A ND2 1 ATOM 373 N N . GLU A 1 66 ? 0.692 13.512 -16.117 1.00 29.97 ? 47 GLU A N 1 ATOM 374 C CA . GLU A 1 66 ? 0.213 14.848 -16.436 1.00 31.91 ? 47 GLU A CA 1 ATOM 375 C C . GLU A 1 66 ? -1.162 15.130 -15.813 1.00 32.15 ? 47 GLU A C 1 ATOM 376 O O . GLU A 1 66 ? -2.046 14.272 -15.821 1.00 28.52 ? 47 GLU A O 1 ATOM 377 C CB . GLU A 1 66 ? 0.138 15.019 -17.954 1.00 30.19 ? 47 GLU A CB 1 ATOM 378 C CG . GLU A 1 66 ? 1.473 14.859 -18.641 1.00 34.48 ? 47 GLU A CG 1 ATOM 379 C CD . GLU A 1 66 ? 1.395 15.028 -20.156 1.00 49.55 ? 47 GLU A CD 1 ATOM 380 O OE1 . GLU A 1 66 ? 0.343 15.504 -20.658 1.00 51.17 ? 47 GLU A OE1 1 ATOM 381 O OE2 . GLU A 1 66 ? 2.399 14.681 -20.835 1.00 49.13 ? 47 GLU A OE2 1 ATOM 382 N N . VAL A 1 67 ? -1.346 16.338 -15.285 1.00 32.49 ? 48 VAL A N 1 ATOM 383 C CA . VAL A 1 67 ? -2.647 16.714 -14.722 1.00 36.08 ? 48 VAL A CA 1 ATOM 384 C C . VAL A 1 67 ? -3.128 18.037 -15.283 1.00 26.35 ? 48 VAL A C 1 ATOM 385 O O . VAL A 1 67 ? -2.349 18.847 -15.744 1.00 25.83 ? 48 VAL A O 1 ATOM 386 C CB . VAL A 1 67 ? -2.633 16.816 -13.167 1.00 31.22 ? 48 VAL A CB 1 ATOM 387 C CG1 . VAL A 1 67 ? -2.207 15.509 -12.549 1.00 32.56 ? 48 VAL A CG1 1 ATOM 388 C CG2 . VAL A 1 67 ? -1.694 17.924 -12.723 1.00 28.57 ? 48 VAL A CG2 1 ATOM 389 N N . ASP A 1 68 ? -4.429 18.251 -15.212 1.00 32.95 ? 49 ASP A N 1 ATOM 390 C CA . ASP A 1 68 ? -5.044 19.482 -15.672 1.00 23.98 ? 49 ASP A CA 1 ATOM 391 C C . ASP A 1 68 ? -5.716 20.131 -14.492 1.00 24.99 ? 49 ASP A C 1 ATOM 392 O O . ASP A 1 68 ? -6.710 19.623 -13.974 1.00 32.55 ? 49 ASP A O 1 ATOM 393 C CB . ASP A 1 68 ? -6.121 19.157 -16.694 1.00 38.26 ? 49 ASP A CB 1 ATOM 394 C CG . ASP A 1 68 ? -5.969 19.949 -17.946 1.00 48.22 ? 49 ASP A CG 1 ATOM 395 O OD1 . ASP A 1 68 ? -4.818 20.386 -18.184 1.00 56.08 ? 49 ASP A OD1 1 ATOM 396 O OD2 . ASP A 1 68 ? -6.973 20.138 -18.681 1.00 62.81 ? 49 ASP A OD2 1 ATOM 397 N N . VAL A 1 69 ? -5.197 21.261 -14.052 1.00 26.02 ? 50 VAL A N 1 ATOM 398 C CA . VAL A 1 69 ? -5.756 21.896 -12.868 1.00 21.80 ? 50 VAL A CA 1 ATOM 399 C C . VAL A 1 69 ? -6.398 23.250 -13.159 1.00 21.28 ? 50 VAL A C 1 ATOM 400 O O . VAL A 1 69 ? -5.925 23.996 -14.014 1.00 25.02 ? 50 VAL A O 1 ATOM 401 C CB . VAL A 1 69 ? -4.671 22.051 -11.833 1.00 21.52 ? 50 VAL A CB 1 ATOM 402 C CG1 . VAL A 1 69 ? -5.239 22.620 -10.538 1.00 17.07 ? 50 VAL A CG1 1 ATOM 403 C CG2 . VAL A 1 69 ? -4.016 20.707 -11.604 1.00 19.59 ? 50 VAL A CG2 1 ATOM 404 N N . VAL A 1 70 ? -7.500 23.539 -12.468 1.00 21.64 ? 51 VAL A N 1 ATOM 405 C CA . VAL A 1 70 ? -8.074 24.883 -12.431 1.00 20.00 ? 51 VAL A CA 1 ATOM 406 C C . VAL A 1 70 ? -7.954 25.424 -11.010 1.00 20.95 ? 51 VAL A C 1 ATOM 407 O O . VAL A 1 70 ? -8.414 24.805 -10.044 1.00 18.47 ? 51 VAL A O 1 ATOM 408 C CB . VAL A 1 70 ? -9.545 24.902 -12.836 1.00 20.44 ? 51 VAL A CB 1 ATOM 409 C CG1 . VAL A 1 70 ? -10.134 26.272 -12.550 1.00 16.49 ? 51 VAL A CG1 1 ATOM 410 C CG2 . VAL A 1 70 ? -9.707 24.516 -14.305 1.00 21.42 ? 51 VAL A CG2 1 ATOM 411 N N . PHE A 1 71 ? -7.325 26.587 -10.891 1.00 22.65 ? 52 PHE A N 1 ATOM 412 C CA . PHE A 1 71 ? -7.064 27.191 -9.587 1.00 24.15 ? 52 PHE A CA 1 ATOM 413 C C . PHE A 1 71 ? -7.073 28.724 -9.652 1.00 21.69 ? 52 PHE A C 1 ATOM 414 O O . PHE A 1 71 ? -6.840 29.306 -10.715 1.00 17.96 ? 52 PHE A O 1 ATOM 415 C CB . PHE A 1 71 ? -5.708 26.722 -9.077 1.00 20.14 ? 52 PHE A CB 1 ATOM 416 C CG . PHE A 1 71 ? -4.581 27.039 -10.016 1.00 18.91 ? 52 PHE A CG 1 ATOM 417 C CD1 . PHE A 1 71 ? -4.309 26.219 -11.101 1.00 21.06 ? 52 PHE A CD1 1 ATOM 418 C CD2 . PHE A 1 71 ? -3.797 28.168 -9.820 1.00 21.46 ? 52 PHE A CD2 1 ATOM 419 C CE1 . PHE A 1 71 ? -3.256 26.517 -11.978 1.00 26.73 ? 52 PHE A CE1 1 ATOM 420 C CE2 . PHE A 1 71 ? -2.752 28.477 -10.686 1.00 21.03 ? 52 PHE A CE2 1 ATOM 421 C CZ . PHE A 1 71 ? -2.478 27.650 -11.768 1.00 22.79 ? 52 PHE A CZ 1 ATOM 422 N N . TRP A 1 72 ? -7.341 29.365 -8.509 1.00 19.22 ? 53 TRP A N 1 ATOM 423 C CA . TRP A 1 72 ? -7.173 30.809 -8.382 1.00 20.42 ? 53 TRP A CA 1 ATOM 424 C C . TRP A 1 72 ? -5.755 31.043 -7.931 1.00 20.31 ? 53 TRP A C 1 ATOM 425 O O . TRP A 1 72 ? -5.291 30.395 -6.994 1.00 20.48 ? 53 TRP A O 1 ATOM 426 C CB . TRP A 1 72 ? -8.104 31.421 -7.335 1.00 18.77 ? 53 TRP A CB 1 ATOM 427 C CG . TRP A 1 72 ? -9.562 31.279 -7.630 1.00 19.69 ? 53 TRP A CG 1 ATOM 428 C CD1 . TRP A 1 72 ? -10.135 30.682 -8.728 1.00 21.11 ? 53 TRP A CD1 1 ATOM 429 C CD2 . TRP A 1 72 ? -10.645 31.754 -6.819 1.00 20.17 ? 53 TRP A CD2 1 ATOM 430 N NE1 . TRP A 1 72 ? -11.509 30.747 -8.636 1.00 24.70 ? 53 TRP A NE1 1 ATOM 431 C CE2 . TRP A 1 72 ? -11.850 31.404 -7.477 1.00 20.56 ? 53 TRP A CE2 1 ATOM 432 C CE3 . TRP A 1 72 ? -10.715 32.449 -5.599 1.00 21.80 ? 53 TRP A CE3 1 ATOM 433 C CZ2 . TRP A 1 72 ? -13.113 31.714 -6.954 1.00 19.47 ? 53 TRP A CZ2 1 ATOM 434 C CZ3 . TRP A 1 72 ? -11.978 32.757 -5.071 1.00 27.08 ? 53 TRP A CZ3 1 ATOM 435 C CH2 . TRP A 1 72 ? -13.161 32.385 -5.752 1.00 22.92 ? 53 TRP A CH2 1 ATOM 436 N N . GLN A 1 73 ? -5.062 31.963 -8.594 1.00 19.54 ? 54 GLN A N 1 ATOM 437 C CA . GLN A 1 73 ? -3.689 32.283 -8.224 1.00 18.52 ? 54 GLN A CA 1 ATOM 438 C C . GLN A 1 73 ? -3.628 33.625 -7.508 1.00 18.06 ? 54 GLN A C 1 ATOM 439 O O . GLN A 1 73 ? -3.320 34.652 -8.102 1.00 19.61 ? 54 GLN A O 1 ATOM 440 C CB . GLN A 1 73 ? -2.791 32.293 -9.458 1.00 17.31 ? 54 GLN A CB 1 ATOM 441 C CG . GLN A 1 73 ? -1.337 32.587 -9.137 1.00 20.61 ? 54 GLN A CG 1 ATOM 442 C CD . GLN A 1 73 ? -0.427 32.417 -10.333 1.00 23.32 ? 54 GLN A CD 1 ATOM 443 O OE1 . GLN A 1 73 ? -0.380 31.357 -10.957 1.00 23.64 ? 54 GLN A OE1 1 ATOM 444 N NE2 . GLN A 1 73 ? 0.305 33.473 -10.662 1.00 39.20 ? 54 GLN A NE2 1 ATOM 445 N N . GLN A 1 74 ? -3.934 33.620 -6.222 1.00 20.45 ? 55 GLN A N 1 ATOM 446 C CA . GLN A 1 74 ? -4.034 34.869 -5.475 1.00 22.01 ? 55 GLN A CA 1 ATOM 447 C C . GLN A 1 74 ? -2.655 35.474 -5.222 1.00 25.01 ? 55 GLN A C 1 ATOM 448 O O . GLN A 1 74 ? -1.832 34.877 -4.530 1.00 26.47 ? 55 GLN A O 1 ATOM 449 C CB . GLN A 1 74 ? -4.751 34.637 -4.149 1.00 22.46 ? 55 GLN A CB 1 ATOM 450 C CG . GLN A 1 74 ? -4.815 35.872 -3.294 1.00 26.43 ? 55 GLN A CG 1 ATOM 451 C CD . GLN A 1 74 ? -5.629 35.665 -2.042 1.00 33.12 ? 55 GLN A CD 1 ATOM 452 O OE1 . GLN A 1 74 ? -6.615 34.927 -2.047 1.00 56.58 ? 55 GLN A OE1 1 ATOM 453 N NE2 . GLN A 1 74 ? -5.216 36.305 -0.952 1.00 36.04 ? 55 GLN A NE2 1 ATOM 454 N N . THR A 1 75 ? -2.412 36.661 -5.781 1.00 21.42 ? 56 THR A N 1 ATOM 455 C CA . THR A 1 75 ? -1.090 37.278 -5.751 1.00 16.55 ? 56 THR A CA 1 ATOM 456 C C . THR A 1 75 ? -1.185 38.657 -5.127 1.00 20.00 ? 56 THR A C 1 ATOM 457 O O . THR A 1 75 ? -2.033 39.456 -5.526 1.00 22.67 ? 56 THR A O 1 ATOM 458 C CB . THR A 1 75 ? -0.533 37.425 -7.164 1.00 18.59 ? 56 THR A CB 1 ATOM 459 O OG1 . THR A 1 75 ? -0.725 36.197 -7.895 1.00 25.99 ? 56 THR A OG1 1 ATOM 460 C CG2 . THR A 1 75 ? 0.947 37.763 -7.103 1.00 23.04 ? 56 THR A CG2 1 ATOM 461 N N . THR A 1 76 ? -0.317 38.950 -4.158 1.00 18.88 ? 57 THR A N 1 ATOM 462 C CA . THR A 1 76 ? -0.423 40.206 -3.394 1.00 20.61 ? 57 THR A CA 1 ATOM 463 C C . THR A 1 76 ? 0.926 40.892 -3.161 1.00 19.54 ? 57 THR A C 1 ATOM 464 O O . THR A 1 76 ? 1.901 40.244 -2.794 1.00 22.83 ? 57 THR A O 1 ATOM 465 C CB . THR A 1 76 ? -1.124 39.968 -2.026 1.00 29.43 ? 57 THR A CB 1 ATOM 466 O OG1 . THR A 1 76 ? -2.503 39.617 -2.237 1.00 30.29 ? 57 THR A OG1 1 ATOM 467 C CG2 . THR A 1 76 ? -1.059 41.225 -1.127 1.00 23.55 ? 57 THR A CG2 1 ATOM 468 N N . TRP A 1 77 ? 0.981 42.201 -3.383 1.00 16.71 ? 58 TRP A N 1 ATOM 469 C CA . TRP A 1 77 ? 2.219 42.950 -3.183 1.00 18.25 ? 58 TRP A CA 1 ATOM 470 C C . TRP A 1 77 ? 1.937 44.413 -2.926 1.00 20.73 ? 58 TRP A C 1 ATOM 471 O O . TRP A 1 77 ? 0.786 44.864 -2.976 1.00 20.31 ? 58 TRP A O 1 ATOM 472 C CB . TRP A 1 77 ? 3.160 42.810 -4.383 1.00 14.88 ? 58 TRP A CB 1 ATOM 473 C CG . TRP A 1 77 ? 2.657 43.495 -5.589 1.00 13.51 ? 58 TRP A CG 1 ATOM 474 C CD1 . TRP A 1 77 ? 2.957 44.757 -5.993 1.00 17.47 ? 58 TRP A CD1 1 ATOM 475 C CD2 . TRP A 1 77 ? 1.743 42.965 -6.559 1.00 17.20 ? 58 TRP A CD2 1 ATOM 476 N NE1 . TRP A 1 77 ? 2.288 45.057 -7.157 1.00 17.49 ? 58 TRP A NE1 1 ATOM 477 C CE2 . TRP A 1 77 ? 1.541 43.980 -7.530 1.00 18.34 ? 58 TRP A CE2 1 ATOM 478 C CE3 . TRP A 1 77 ? 1.084 41.741 -6.701 1.00 15.76 ? 58 TRP A CE3 1 ATOM 479 C CZ2 . TRP A 1 77 ? 0.701 43.799 -8.638 1.00 14.12 ? 58 TRP A CZ2 1 ATOM 480 C CZ3 . TRP A 1 77 ? 0.241 41.569 -7.798 1.00 17.95 ? 58 TRP A CZ3 1 ATOM 481 C CH2 . TRP A 1 77 ? 0.065 42.598 -8.758 1.00 14.79 ? 58 TRP A CH2 1 ATOM 482 N N . SER A 1 78 ? 3.000 45.162 -2.670 1.00 19.00 ? 59 SER A N 1 ATOM 483 C CA . SER A 1 78 ? 2.846 46.577 -2.376 1.00 21.01 ? 59 SER A CA 1 ATOM 484 C C . SER A 1 78 ? 3.518 47.483 -3.409 1.00 18.51 ? 59 SER A C 1 ATOM 485 O O . SER A 1 78 ? 4.654 47.238 -3.799 1.00 22.35 ? 59 SER A O 1 ATOM 486 C CB . SER A 1 78 ? 3.369 46.874 -0.978 1.00 22.89 ? 59 SER A CB 1 ATOM 487 O OG . SER A 1 78 ? 3.230 48.245 -0.706 1.00 26.92 ? 59 SER A OG 1 ATOM 488 N N . ASP A 1 79 ? 2.797 48.513 -3.856 1.00 18.84 ? 60 ASP A N 1 ATOM 489 C CA . ASP A 1 79 ? 3.327 49.513 -4.788 1.00 21.44 ? 60 ASP A CA 1 ATOM 490 C C . ASP A 1 79 ? 2.927 50.942 -4.379 1.00 29.81 ? 60 ASP A C 1 ATOM 491 O O . ASP A 1 79 ? 1.839 51.413 -4.741 1.00 25.53 ? 60 ASP A O 1 ATOM 492 C CB . ASP A 1 79 ? 2.831 49.223 -6.205 1.00 23.37 ? 60 ASP A CB 1 ATOM 493 C CG . ASP A 1 79 ? 3.621 49.980 -7.288 1.00 31.68 ? 60 ASP A CG 1 ATOM 494 O OD1 . ASP A 1 79 ? 4.222 51.049 -6.990 1.00 30.05 ? 60 ASP A OD1 1 ATOM 495 O OD2 . ASP A 1 79 ? 3.644 49.488 -8.449 1.00 26.31 ? 60 ASP A OD2 1 ATOM 496 N N . ARG A 1 80 ? 3.814 51.628 -3.647 1.00 31.34 ? 61 ARG A N 1 ATOM 497 C CA . ARG A 1 80 ? 3.506 52.951 -3.071 1.00 33.33 ? 61 ARG A CA 1 ATOM 498 C C . ARG A 1 80 ? 3.273 54.030 -4.131 1.00 23.63 ? 61 ARG A C 1 ATOM 499 O O . ARG A 1 80 ? 2.662 55.053 -3.857 1.00 25.84 ? 61 ARG A O 1 ATOM 500 C CB . ARG A 1 80 ? 4.602 53.414 -2.097 1.00 42.85 ? 61 ARG A CB 1 ATOM 501 C CG . ARG A 1 80 ? 5.022 52.375 -1.066 1.00 49.21 ? 61 ARG A CG 1 ATOM 502 C CD . ARG A 1 80 ? 4.080 52.286 0.137 1.00 59.91 ? 61 ARG A CD 1 ATOM 503 N NE . ARG A 1 80 ? 4.662 51.442 1.194 1.00 78.46 ? 61 ARG A NE 1 ATOM 504 C CZ . ARG A 1 80 ? 4.076 50.372 1.738 1.00 79.93 ? 61 ARG A CZ 1 ATOM 505 N NH1 . ARG A 1 80 ? 2.854 49.999 1.352 1.00 74.32 ? 61 ARG A NH1 1 ATOM 506 N NH2 . ARG A 1 80 ? 4.712 49.674 2.679 1.00 69.43 ? 61 ARG A NH2 1 ATOM 507 N N . THR A 1 81 ? 3.779 53.800 -5.334 1.00 24.69 ? 62 THR A N 1 ATOM 508 C CA . THR A 1 81 ? 3.518 54.664 -6.492 1.00 25.71 ? 62 THR A CA 1 ATOM 509 C C . THR A 1 81 ? 2.013 54.849 -6.764 1.00 21.85 ? 62 THR A C 1 ATOM 510 O O . THR A 1 81 ? 1.591 55.844 -7.327 1.00 19.94 ? 62 THR A O 1 ATOM 511 C CB . THR A 1 81 ? 4.178 54.041 -7.766 1.00 34.06 ? 62 THR A CB 1 ATOM 512 O OG1 . THR A 1 81 ? 5.584 53.843 -7.543 1.00 35.49 ? 62 THR A OG1 1 ATOM 513 C CG2 . THR A 1 81 ? 3.968 54.903 -9.018 1.00 38.10 ? 62 THR A CG2 1 ATOM 514 N N . LEU A 1 82 ? 1.204 53.874 -6.368 1.00 24.65 ? 63 LEU A N 1 ATOM 515 C CA . LEU A 1 82 ? -0.219 53.926 -6.647 1.00 18.37 ? 63 LEU A CA 1 ATOM 516 C C . LEU A 1 82 ? -1.028 54.602 -5.543 1.00 20.45 ? 63 LEU A C 1 ATOM 517 O O . LEU A 1 82 ? -2.230 54.813 -5.701 1.00 28.60 ? 63 LEU A O 1 ATOM 518 C CB . LEU A 1 82 ? -0.751 52.515 -6.869 1.00 17.62 ? 63 LEU A CB 1 ATOM 519 C CG . LEU A 1 82 ? -0.016 51.687 -7.915 1.00 21.33 ? 63 LEU A CG 1 ATOM 520 C CD1 . LEU A 1 82 ? -0.377 50.212 -7.776 1.00 19.39 ? 63 LEU A CD1 1 ATOM 521 C CD2 . LEU A 1 82 ? -0.372 52.199 -9.301 1.00 17.27 ? 63 LEU A CD2 1 ATOM 522 N N . ALA A 1 83 ? -0.391 54.932 -4.426 1.00 15.68 ? 64 ALA A N 1 ATOM 523 C CA . ALA A 1 83 ? -1.139 55.366 -3.250 1.00 18.65 ? 64 ALA A CA 1 ATOM 524 C C . ALA A 1 83 ? -1.788 56.742 -3.428 1.00 24.45 ? 64 ALA A C 1 ATOM 525 O O . ALA A 1 83 ? -1.321 57.547 -4.229 1.00 25.98 ? 64 ALA A O 1 ATOM 526 C CB . ALA A 1 83 ? -0.267 55.348 -2.028 1.00 20.53 ? 64 ALA A CB 1 ATOM 527 N N . TRP A 1 84 ? -2.874 56.989 -2.688 1.00 24.38 ? 65 TRP A N 1 ATOM 528 C CA . TRP A 1 84 ? -3.545 58.290 -2.663 1.00 21.82 ? 65 TRP A CA 1 ATOM 529 C C . TRP A 1 84 ? -4.120 58.599 -1.274 1.00 25.67 ? 65 TRP A C 1 ATOM 530 O O . TRP A 1 84 ? -4.247 57.709 -0.439 1.00 23.46 ? 65 TRP A O 1 ATOM 531 C CB . TRP A 1 84 ? -4.638 58.363 -3.735 1.00 23.11 ? 65 TRP A CB 1 ATOM 532 C CG . TRP A 1 84 ? -5.850 57.477 -3.499 1.00 26.56 ? 65 TRP A CG 1 ATOM 533 C CD1 . TRP A 1 84 ? -7.006 57.820 -2.844 1.00 28.15 ? 65 TRP A CD1 1 ATOM 534 C CD2 . TRP A 1 84 ? -6.033 56.113 -3.942 1.00 27.77 ? 65 TRP A CD2 1 ATOM 535 N NE1 . TRP A 1 84 ? -7.884 56.758 -2.843 1.00 25.04 ? 65 TRP A NE1 1 ATOM 536 C CE2 . TRP A 1 84 ? -7.314 55.702 -3.506 1.00 22.17 ? 65 TRP A CE2 1 ATOM 537 C CE3 . TRP A 1 84 ? -5.227 55.195 -4.641 1.00 21.94 ? 65 TRP A CE3 1 ATOM 538 C CZ2 . TRP A 1 84 ? -7.805 54.418 -3.747 1.00 20.76 ? 65 TRP A CZ2 1 ATOM 539 C CZ3 . TRP A 1 84 ? -5.717 53.925 -4.880 1.00 16.26 ? 65 TRP A CZ3 1 ATOM 540 C CH2 . TRP A 1 84 ? -6.998 53.548 -4.441 1.00 19.32 ? 65 TRP A CH2 1 ATOM 541 N N . ASN A 1 85 ? -4.468 59.836 -1.026 1.00 35.56 ? 66 ASN A N 1 ATOM 542 C CA . ASN A 1 85 ? -5.066 60.200 0.221 1.00 36.34 ? 66 ASN A CA 1 ATOM 543 C C . ASN A 1 85 ? -6.545 60.095 0.067 1.00 47.70 ? 66 ASN A C 1 ATOM 544 O O . ASN A 1 85 ? -7.113 60.669 -0.827 1.00 51.33 ? 66 ASN A O 1 ATOM 545 C CB . ASN A 1 85 ? -4.689 61.615 0.566 1.00 41.89 ? 66 ASN A CB 1 ATOM 546 C CG . ASN A 1 85 ? -5.475 62.162 1.721 1.00 63.20 ? 66 ASN A CG 1 ATOM 547 O OD1 . ASN A 1 85 ? -6.219 61.459 2.378 1.00 52.97 ? 66 ASN A OD1 1 ATOM 548 N ND2 . ASN A 1 85 ? -5.310 63.442 1.972 1.00 68.09 ? 66 ASN A ND2 1 ATOM 549 N N . SER A 1 86 ? -7.167 59.349 0.959 1.00 48.82 ? 67 SER A N 1 ATOM 550 C CA . SER A 1 86 ? -8.546 58.960 0.832 1.00 46.41 ? 67 SER A CA 1 ATOM 551 C C . SER A 1 86 ? -9.428 59.522 1.927 1.00 54.24 ? 67 SER A C 1 ATOM 552 O O . SER A 1 86 ? -10.300 58.854 2.423 1.00 55.92 ? 67 SER A O 1 ATOM 553 C CB . SER A 1 86 ? -8.652 57.470 0.801 1.00 44.74 ? 67 SER A CB 1 ATOM 554 O OG . SER A 1 86 ? -8.452 56.976 2.074 1.00 61.94 ? 67 SER A OG 1 ATOM 555 N N . SER A 1 87 ? -9.177 60.754 2.330 1.00 66.76 ? 68 SER A N 1 ATOM 556 C CA . SER A 1 87 ? -9.925 61.341 3.416 1.00 69.96 ? 68 SER A CA 1 ATOM 557 C C . SER A 1 87 ? -11.393 61.430 3.094 1.00 66.78 ? 68 SER A C 1 ATOM 558 O O . SER A 1 87 ? -12.210 61.024 3.897 1.00 70.38 ? 68 SER A O 1 ATOM 559 C CB . SER A 1 87 ? -9.380 62.735 3.719 1.00 66.45 ? 68 SER A CB 1 ATOM 560 O OG . SER A 1 87 ? -9.924 63.257 4.905 1.00 55.88 ? 68 SER A OG 1 ATOM 561 N N . HIS A 1 88 ? -11.736 61.888 1.912 1.00 57.24 ? 69 HIS A N 1 ATOM 562 C CA . HIS A 1 88 ? -13.117 61.876 1.525 1.00 62.93 ? 69 HIS A CA 1 ATOM 563 C C . HIS A 1 88 ? -13.128 61.276 0.181 1.00 67.47 ? 69 HIS A C 1 ATOM 564 O O . HIS A 1 88 ? -13.449 61.907 -0.801 1.00 69.19 ? 69 HIS A O 1 ATOM 565 C CB . HIS A 1 88 ? -13.667 63.282 1.511 1.00 77.83 ? 69 HIS A CB 1 ATOM 566 C CG . HIS A 1 88 ? -13.802 63.884 2.870 1.00 86.73 ? 69 HIS A CG 1 ATOM 567 N ND1 . HIS A 1 88 ? -14.611 63.344 3.840 1.00 76.68 ? 69 HIS A ND1 1 ATOM 568 C CD2 . HIS A 1 88 ? -13.231 64.976 3.419 1.00 87.79 ? 69 HIS A CD2 1 ATOM 569 C CE1 . HIS A 1 88 ? -14.531 64.075 4.930 1.00 84.14 ? 69 HIS A CE1 1 ATOM 570 N NE2 . HIS A 1 88 ? -13.698 65.070 4.702 1.00 89.80 ? 69 HIS A NE2 1 ATOM 571 N N . SER A 1 89 ? -12.770 60.013 0.152 1.00 59.32 ? 70 SER A N 1 ATOM 572 C CA . SER A 1 89 ? -12.444 59.390 -1.071 1.00 51.48 ? 70 SER A CA 1 ATOM 573 C C . SER A 1 89 ? -12.635 57.938 -1.004 1.00 45.99 ? 70 SER A C 1 ATOM 574 O O . SER A 1 89 ? -12.659 57.363 0.042 1.00 40.49 ? 70 SER A O 1 ATOM 575 C CB . SER A 1 89 ? -11.007 59.685 -1.384 1.00 56.44 ? 70 SER A CB 1 ATOM 576 O OG . SER A 1 89 ? -10.804 61.071 -1.381 1.00 60.90 ? 70 SER A OG 1 ATOM 577 N N . PRO A 1 90 ? -12.772 57.346 -2.241 1.00 48.47 ? 71 PRO A N 1 ATOM 578 C CA . PRO A 1 90 ? -12.816 55.892 -2.220 1.00 37.25 ? 71 PRO A CA 1 ATOM 579 C C . PRO A 1 90 ? -11.521 55.354 -1.748 1.00 32.36 ? 71 PRO A C 1 ATOM 580 O O . PRO A 1 90 ? -10.530 55.959 -1.970 1.00 36.37 ? 71 PRO A O 1 ATOM 581 C CB . PRO A 1 90 ? -12.972 55.540 -3.673 1.00 38.96 ? 71 PRO A CB 1 ATOM 582 C CG . PRO A 1 90 ? -13.746 56.645 -4.225 1.00 43.82 ? 71 PRO A CG 1 ATOM 583 C CD . PRO A 1 90 ? -12.995 57.777 -3.686 1.00 40.38 ? 71 PRO A CD 1 ATOM 584 N N . ASP A 1 91 ? -11.548 54.235 -1.067 1.00 33.70 ? 72 ASP A N 1 ATOM 585 C CA . ASP A 1 91 ? -10.332 53.611 -0.545 1.00 36.82 ? 72 ASP A CA 1 ATOM 586 C C . ASP A 1 91 ? -9.856 52.428 -1.416 1.00 30.76 ? 72 ASP A C 1 ATOM 587 O O . ASP A 1 91 ? -8.862 51.773 -1.101 1.00 30.90 ? 72 ASP A O 1 ATOM 588 C CB . ASP A 1 91 ? -10.556 53.162 0.902 1.00 39.48 ? 72 ASP A CB 1 ATOM 589 C CG . ASP A 1 91 ? -11.891 52.443 1.086 1.00 52.85 ? 72 ASP A CG 1 ATOM 590 O OD1 . ASP A 1 91 ? -12.687 52.427 0.109 1.00 52.30 ? 72 ASP A OD1 1 ATOM 591 O OD2 . ASP A 1 91 ? -12.155 51.912 2.203 1.00 54.50 ? 72 ASP A OD2 1 ATOM 592 N N . GLN A 1 92 ? -10.556 52.183 -2.522 1.00 25.06 ? 73 GLN A N 1 ATOM 593 C CA . GLN A 1 92 ? -10.204 51.109 -3.442 1.00 23.08 ? 73 GLN A CA 1 ATOM 594 C C . GLN A 1 92 ? -10.741 51.346 -4.869 1.00 22.76 ? 73 GLN A C 1 ATOM 595 O O . GLN A 1 92 ? -11.748 52.025 -5.061 1.00 25.25 ? 73 GLN A O 1 ATOM 596 C CB . GLN A 1 92 ? -10.778 49.812 -2.912 1.00 30.62 ? 73 GLN A CB 1 ATOM 597 C CG . GLN A 1 92 ? -12.278 49.909 -2.756 1.00 36.46 ? 73 GLN A CG 1 ATOM 598 C CD . GLN A 1 92 ? -12.911 48.577 -2.537 1.00 46.96 ? 73 GLN A CD 1 ATOM 599 O OE1 . GLN A 1 92 ? -12.362 47.724 -1.839 1.00 50.60 ? 73 GLN A OE1 1 ATOM 600 N NE2 . GLN A 1 92 ? -14.074 48.373 -3.142 1.00 55.59 ? 73 GLN A NE2 1 ATOM 601 N N . VAL A 1 93 ? -10.067 50.771 -5.861 1.00 18.68 ? 74 VAL A N 1 ATOM 602 C CA . VAL A 1 93 ? -10.497 50.830 -7.257 1.00 15.07 ? 74 VAL A CA 1 ATOM 603 C C . VAL A 1 93 ? -10.035 49.564 -7.957 1.00 15.84 ? 74 VAL A C 1 ATOM 604 O O . VAL A 1 93 ? -9.148 48.862 -7.461 1.00 16.50 ? 74 VAL A O 1 ATOM 605 C CB . VAL A 1 93 ? -9.916 52.055 -8.031 1.00 15.69 ? 74 VAL A CB 1 ATOM 606 C CG1 . VAL A 1 93 ? -10.481 53.365 -7.504 1.00 18.54 ? 74 VAL A CG1 1 ATOM 607 C CG2 . VAL A 1 93 ? -8.413 52.073 -7.941 1.00 15.41 ? 74 VAL A CG2 1 ATOM 608 N N . SER A 1 94 ? -10.634 49.269 -9.109 1.00 16.21 ? 75 SER A N 1 ATOM 609 C CA . SER A 1 94 ? -10.209 48.131 -9.918 1.00 13.68 ? 75 SER A CA 1 ATOM 610 C C . SER A 1 94 ? -9.470 48.655 -11.134 1.00 14.33 ? 75 SER A C 1 ATOM 611 O O . SER A 1 94 ? -9.943 49.562 -11.820 1.00 16.64 ? 75 SER A O 1 ATOM 612 C CB . SER A 1 94 ? -11.398 47.268 -10.339 1.00 17.49 ? 75 SER A CB 1 ATOM 613 O OG . SER A 1 94 ? -11.799 46.419 -9.277 1.00 22.27 ? 75 SER A OG 1 ATOM 614 N N . VAL A 1 95 ? -8.300 48.089 -11.395 1.00 11.11 ? 76 VAL A N 1 ATOM 615 C CA . VAL A 1 95 ? -7.419 48.612 -12.428 1.00 15.03 ? 76 VAL A CA 1 ATOM 616 C C . VAL A 1 95 ? -7.045 47.513 -13.421 1.00 17.93 ? 76 VAL A C 1 ATOM 617 O O . VAL A 1 95 ? -6.652 46.417 -13.009 1.00 18.77 ? 76 VAL A O 1 ATOM 618 C CB . VAL A 1 95 ? -6.118 49.150 -11.787 1.00 16.43 ? 76 VAL A CB 1 ATOM 619 C CG1 . VAL A 1 95 ? -5.170 49.686 -12.848 1.00 18.27 ? 76 VAL A CG1 1 ATOM 620 C CG2 . VAL A 1 95 ? -6.424 50.204 -10.763 1.00 16.53 ? 76 VAL A CG2 1 ATOM 621 N N . PRO A 1 96 ? -7.136 47.799 -14.733 1.00 16.36 ? 77 PRO A N 1 ATOM 622 C CA . PRO A 1 96 ? -6.675 46.805 -15.721 1.00 13.18 ? 77 PRO A CA 1 ATOM 623 C C . PRO A 1 96 ? -5.192 46.552 -15.526 1.00 18.27 ? 77 PRO A C 1 ATOM 624 O O . PRO A 1 96 ? -4.446 47.530 -15.386 1.00 23.62 ? 77 PRO A O 1 ATOM 625 C CB . PRO A 1 96 ? -6.893 47.503 -17.056 1.00 14.46 ? 77 PRO A CB 1 ATOM 626 C CG . PRO A 1 96 ? -7.934 48.587 -16.763 1.00 18.93 ? 77 PRO A CG 1 ATOM 627 C CD . PRO A 1 96 ? -7.620 49.040 -15.365 1.00 17.63 ? 77 PRO A CD 1 ATOM 628 N N . ILE A 1 97 ? -4.766 45.288 -15.482 1.00 20.35 ? 78 ILE A N 1 ATOM 629 C CA . ILE A 1 97 ? -3.374 44.967 -15.146 1.00 15.81 ? 78 ILE A CA 1 ATOM 630 C C . ILE A 1 97 ? -2.398 45.539 -16.166 1.00 19.59 ? 78 ILE A C 1 ATOM 631 O O . ILE A 1 97 ? -1.216 45.708 -15.879 1.00 25.44 ? 78 ILE A O 1 ATOM 632 C CB . ILE A 1 97 ? -3.112 43.452 -14.984 1.00 13.86 ? 78 ILE A CB 1 ATOM 633 C CG1 . ILE A 1 97 ? -3.443 42.692 -16.268 1.00 14.43 ? 78 ILE A CG1 1 ATOM 634 C CG2 . ILE A 1 97 ? -3.874 42.897 -13.803 1.00 15.00 ? 78 ILE A CG2 1 ATOM 635 C CD1 . ILE A 1 97 ? -3.014 41.266 -16.239 1.00 11.45 ? 78 ILE A CD1 1 ATOM 636 N N . SER A 1 98 ? -2.881 45.836 -17.364 1.00 16.43 ? 79 SER A N 1 ATOM 637 C CA . SER A 1 98 ? -2.013 46.471 -18.348 1.00 20.55 ? 79 SER A CA 1 ATOM 638 C C . SER A 1 98 ? -1.476 47.856 -17.869 1.00 21.29 ? 79 SER A C 1 ATOM 639 O O . SER A 1 98 ? -0.474 48.351 -18.379 1.00 22.11 ? 79 SER A O 1 ATOM 640 C CB . SER A 1 98 ? -2.721 46.549 -19.701 1.00 19.79 ? 79 SER A CB 1 ATOM 641 O OG . SER A 1 98 ? -3.796 47.469 -19.655 1.00 31.98 ? 79 SER A OG 1 ATOM 642 N N . SER A 1 99 ? -2.124 48.455 -16.873 1.00 18.87 ? 80 SER A N 1 ATOM 643 C CA . SER A 1 99 ? -1.691 49.742 -16.344 1.00 20.26 ? 80 SER A CA 1 ATOM 644 C C . SER A 1 99 ? -0.884 49.663 -15.046 1.00 26.85 ? 80 SER A C 1 ATOM 645 O O . SER A 1 99 ? -0.720 50.674 -14.376 1.00 29.45 ? 80 SER A O 1 ATOM 646 C CB . SER A 1 99 ? -2.904 50.641 -16.086 1.00 21.40 ? 80 SER A CB 1 ATOM 647 O OG . SER A 1 99 ? -3.787 50.643 -17.194 1.00 31.61 ? 80 SER A OG 1 ATOM 648 N N . LEU A 1 100 ? -0.397 48.479 -14.681 1.00 24.14 ? 81 LEU A N 1 ATOM 649 C CA . LEU A 1 100 ? 0.294 48.280 -13.401 1.00 21.27 ? 81 LEU A CA 1 ATOM 650 C C . LEU A 1 100 ? 1.533 47.454 -13.599 1.00 23.01 ? 81 LEU A C 1 ATOM 651 O O . LEU A 1 100 ? 1.570 46.595 -14.490 1.00 24.62 ? 81 LEU A O 1 ATOM 652 C CB . LEU A 1 100 ? -0.583 47.456 -12.454 1.00 23.36 ? 81 LEU A CB 1 ATOM 653 C CG . LEU A 1 100 ? -1.863 48.072 -11.944 1.00 24.35 ? 81 LEU A CG 1 ATOM 654 C CD1 . LEU A 1 100 ? -2.494 47.132 -10.980 1.00 18.46 ? 81 LEU A CD1 1 ATOM 655 C CD2 . LEU A 1 100 ? -1.483 49.347 -11.249 1.00 30.69 ? 81 LEU A CD2 1 ATOM 656 N N . TRP A 1 101 ? 2.528 47.641 -12.739 1.00 18.17 ? 82 TRP A N 1 ATOM 657 C CA . TRP A 1 101 ? 3.573 46.631 -12.667 1.00 17.96 ? 82 TRP A CA 1 ATOM 658 C C . TRP A 1 101 ? 2.989 45.356 -12.051 1.00 18.68 ? 82 TRP A C 1 ATOM 659 O O . TRP A 1 101 ? 2.193 45.414 -11.120 1.00 22.37 ? 82 TRP A O 1 ATOM 660 C CB . TRP A 1 101 ? 4.778 47.103 -11.865 1.00 17.74 ? 82 TRP A CB 1 ATOM 661 C CG . TRP A 1 101 ? 5.812 46.037 -11.734 1.00 19.24 ? 82 TRP A CG 1 ATOM 662 C CD1 . TRP A 1 101 ? 6.838 45.772 -12.601 1.00 20.13 ? 82 TRP A CD1 1 ATOM 663 C CD2 . TRP A 1 101 ? 5.909 45.066 -10.685 1.00 20.41 ? 82 TRP A CD2 1 ATOM 664 N NE1 . TRP A 1 101 ? 7.575 44.704 -12.147 1.00 20.25 ? 82 TRP A NE1 1 ATOM 665 C CE2 . TRP A 1 101 ? 7.025 44.249 -10.977 1.00 20.50 ? 82 TRP A CE2 1 ATOM 666 C CE3 . TRP A 1 101 ? 5.152 44.802 -9.532 1.00 17.91 ? 82 TRP A CE3 1 ATOM 667 C CZ2 . TRP A 1 101 ? 7.410 43.185 -10.152 1.00 19.21 ? 82 TRP A CZ2 1 ATOM 668 C CZ3 . TRP A 1 101 ? 5.535 43.748 -8.704 1.00 15.69 ? 82 TRP A CZ3 1 ATOM 669 C CH2 . TRP A 1 101 ? 6.660 42.953 -9.021 1.00 17.95 ? 82 TRP A CH2 1 ATOM 670 N N . VAL A 1 102 ? 3.398 44.210 -12.574 1.00 19.37 ? 83 VAL A N 1 ATOM 671 C CA . VAL A 1 102 ? 2.920 42.914 -12.119 1.00 19.16 ? 83 VAL A CA 1 ATOM 672 C C . VAL A 1 102 ? 4.118 41.970 -12.051 1.00 19.18 ? 83 VAL A C 1 ATOM 673 O O . VAL A 1 102 ? 4.961 41.979 -12.945 1.00 20.97 ? 83 VAL A O 1 ATOM 674 C CB . VAL A 1 102 ? 1.860 42.350 -13.101 1.00 21.45 ? 83 VAL A CB 1 ATOM 675 C CG1 . VAL A 1 102 ? 1.803 40.841 -13.038 1.00 26.35 ? 83 VAL A CG1 1 ATOM 676 C CG2 . VAL A 1 102 ? 0.484 42.947 -12.819 1.00 20.30 ? 83 VAL A CG2 1 ATOM 677 N N . PRO A 1 103 ? 4.197 41.146 -10.989 1.00 18.65 ? 84 PRO A N 1 ATOM 678 C CA . PRO A 1 103 ? 5.344 40.230 -10.873 1.00 15.11 ? 84 PRO A CA 1 ATOM 679 C C . PRO A 1 103 ? 5.343 39.179 -11.980 1.00 13.93 ? 84 PRO A C 1 ATOM 680 O O . PRO A 1 103 ? 4.267 38.709 -12.339 1.00 11.66 ? 84 PRO A O 1 ATOM 681 C CB . PRO A 1 103 ? 5.141 39.585 -9.491 1.00 14.58 ? 84 PRO A CB 1 ATOM 682 C CG . PRO A 1 103 ? 3.685 39.777 -9.174 1.00 14.87 ? 84 PRO A CG 1 ATOM 683 C CD . PRO A 1 103 ? 3.258 41.047 -9.848 1.00 14.44 ? 84 PRO A CD 1 ATOM 684 N N . ASP A 1 104 ? 6.524 38.840 -12.506 1.00 18.63 ? 85 ASP A N 1 ATOM 685 C CA . ASP A 1 104 ? 6.682 37.862 -13.605 1.00 14.13 ? 85 ASP A CA 1 ATOM 686 C C . ASP A 1 104 ? 6.749 36.410 -13.137 1.00 16.70 ? 85 ASP A C 1 ATOM 687 O O . ASP A 1 104 ? 7.714 35.694 -13.423 1.00 20.19 ? 85 ASP A O 1 ATOM 688 C CB . ASP A 1 104 ? 7.928 38.177 -14.463 1.00 16.31 ? 85 ASP A CB 1 ATOM 689 C CG . ASP A 1 104 ? 9.257 38.130 -13.665 1.00 21.71 ? 85 ASP A CG 1 ATOM 690 O OD1 . ASP A 1 104 ? 9.260 38.410 -12.438 1.00 23.56 ? 85 ASP A OD1 1 ATOM 691 O OD2 . ASP A 1 104 ? 10.309 37.822 -14.277 1.00 19.36 ? 85 ASP A OD2 1 ATOM 692 N N . LEU A 1 105 ? 5.716 35.966 -12.431 1.00 17.23 ? 86 LEU A N 1 ATOM 693 C CA . LEU A 1 105 ? 5.664 34.597 -11.932 1.00 16.34 ? 86 LEU A CA 1 ATOM 694 C C . LEU A 1 105 ? 5.402 33.593 -13.070 1.00 21.21 ? 86 LEU A C 1 ATOM 695 O O . LEU A 1 105 ? 4.705 33.907 -14.041 1.00 21.70 ? 86 LEU A O 1 ATOM 696 C CB . LEU A 1 105 ? 4.590 34.482 -10.850 1.00 16.88 ? 86 LEU A CB 1 ATOM 697 C CG . LEU A 1 105 ? 4.775 35.501 -9.714 1.00 14.95 ? 86 LEU A CG 1 ATOM 698 C CD1 . LEU A 1 105 ? 3.605 35.452 -8.746 1.00 12.56 ? 86 LEU A CD1 1 ATOM 699 C CD2 . LEU A 1 105 ? 6.102 35.272 -8.983 1.00 15.67 ? 86 LEU A CD2 1 ATOM 700 N N . ALA A 1 106 ? 5.987 32.398 -12.954 1.00 24.29 ? 87 ALA A N 1 ATOM 701 C CA . ALA A 1 106 ? 5.779 31.306 -13.910 1.00 15.09 ? 87 ALA A CA 1 ATOM 702 C C . ALA A 1 106 ? 5.819 30.004 -13.154 1.00 19.47 ? 87 ALA A C 1 ATOM 703 O O . ALA A 1 106 ? 6.500 29.904 -12.124 1.00 23.29 ? 87 ALA A O 1 ATOM 704 C CB . ALA A 1 106 ? 6.850 31.310 -14.967 1.00 14.95 ? 87 ALA A CB 1 ATOM 705 N N . ALA A 1 107 ? 5.091 29.010 -13.663 1.00 19.59 ? 88 ALA A N 1 ATOM 706 C CA . ALA A 1 107 ? 5.099 27.655 -13.098 1.00 18.44 ? 88 ALA A CA 1 ATOM 707 C C . ALA A 1 107 ? 6.167 26.831 -13.817 1.00 18.39 ? 88 ALA A C 1 ATOM 708 O O . ALA A 1 107 ? 6.057 26.566 -15.021 1.00 17.77 ? 88 ALA A O 1 ATOM 709 C CB . ALA A 1 107 ? 3.716 27.003 -13.217 1.00 15.45 ? 88 ALA A CB 1 ATOM 710 N N . TYR A 1 108 ? 7.204 26.447 -13.075 1.00 18.70 ? 89 TYR A N 1 ATOM 711 C CA . TYR A 1 108 ? 8.373 25.772 -13.651 1.00 18.52 ? 89 TYR A CA 1 ATOM 712 C C . TYR A 1 108 ? 8.064 24.423 -14.302 1.00 20.35 ? 89 TYR A C 1 ATOM 713 O O . TYR A 1 108 ? 8.735 24.023 -15.251 1.00 26.88 ? 89 TYR A O 1 ATOM 714 C CB . TYR A 1 108 ? 9.465 25.597 -12.592 1.00 23.59 ? 89 TYR A CB 1 ATOM 715 C CG . TYR A 1 108 ? 10.290 26.839 -12.354 1.00 26.97 ? 89 TYR A CG 1 ATOM 716 C CD1 . TYR A 1 108 ? 9.756 27.939 -11.703 1.00 29.97 ? 89 TYR A CD1 1 ATOM 717 C CD2 . TYR A 1 108 ? 11.603 26.909 -12.786 1.00 27.65 ? 89 TYR A CD2 1 ATOM 718 C CE1 . TYR A 1 108 ? 10.518 29.087 -11.492 1.00 36.65 ? 89 TYR A CE1 1 ATOM 719 C CE2 . TYR A 1 108 ? 12.374 28.038 -12.580 1.00 34.57 ? 89 TYR A CE2 1 ATOM 720 C CZ . TYR A 1 108 ? 11.831 29.128 -11.933 1.00 37.03 ? 89 TYR A CZ 1 ATOM 721 O OH . TYR A 1 108 ? 12.603 30.254 -11.729 1.00 33.02 ? 89 TYR A OH 1 ATOM 722 N N . ASN A 1 109 ? 7.059 23.716 -13.797 1.00 17.58 ? 90 ASN A N 1 ATOM 723 C CA . ASN A 1 109 ? 6.715 22.407 -14.347 1.00 14.40 ? 90 ASN A CA 1 ATOM 724 C C . ASN A 1 109 ? 5.390 22.417 -15.134 1.00 20.41 ? 90 ASN A C 1 ATOM 725 O O . ASN A 1 109 ? 4.718 21.390 -15.294 1.00 20.47 ? 90 ASN A O 1 ATOM 726 C CB . ASN A 1 109 ? 6.730 21.319 -13.257 1.00 13.42 ? 90 ASN A CB 1 ATOM 727 C CG . ASN A 1 109 ? 5.760 21.599 -12.116 1.00 20.33 ? 90 ASN A CG 1 ATOM 728 O OD1 . ASN A 1 109 ? 5.722 22.696 -11.550 1.00 23.09 ? 90 ASN A OD1 1 ATOM 729 N ND2 . ASN A 1 109 ? 4.953 20.603 -11.785 1.00 26.63 ? 90 ASN A ND2 1 ATOM 730 N N . ALA A 1 110 ? 5.013 23.596 -15.616 1.00 22.16 ? 91 ALA A N 1 ATOM 731 C CA . ALA A 1 110 ? 3.856 23.728 -16.493 1.00 22.22 ? 91 ALA A CA 1 ATOM 732 C C . ALA A 1 110 ? 4.248 23.233 -17.896 1.00 20.76 ? 91 ALA A C 1 ATOM 733 O O . ALA A 1 110 ? 5.386 23.412 -18.340 1.00 17.03 ? 91 ALA A O 1 ATOM 734 C CB . ALA A 1 110 ? 3.377 25.182 -16.523 1.00 17.84 ? 91 ALA A CB 1 ATOM 735 N N . ILE A 1 111 ? 3.322 22.579 -18.583 1.00 22.43 ? 92 ILE A N 1 ATOM 736 C CA . ILE A 1 111 ? 3.608 22.126 -19.942 1.00 28.12 ? 92 ILE A CA 1 ATOM 737 C C . ILE A 1 111 ? 2.660 22.753 -20.973 1.00 25.57 ? 92 ILE A C 1 ATOM 738 O O . ILE A 1 111 ? 2.599 22.316 -22.121 1.00 24.43 ? 92 ILE A O 1 ATOM 739 C CB . ILE A 1 111 ? 3.599 20.589 -20.049 1.00 26.67 ? 92 ILE A CB 1 ATOM 740 C CG1 . ILE A 1 111 ? 2.291 20.019 -19.488 1.00 25.52 ? 92 ILE A CG1 1 ATOM 741 C CG2 . ILE A 1 111 ? 4.800 19.994 -19.335 1.00 20.93 ? 92 ILE A CG2 1 ATOM 742 C CD1 . ILE A 1 111 ? 2.180 18.516 -19.655 1.00 33.32 ? 92 ILE A CD1 1 ATOM 743 N N . SER A 1 112 ? 1.926 23.774 -20.538 1.00 20.82 ? 93 SER A N 1 ATOM 744 C CA . SER A 1 112 ? 1.059 24.555 -21.414 1.00 25.19 ? 93 SER A CA 1 ATOM 745 C C . SER A 1 112 ? 1.047 25.966 -20.849 1.00 25.51 ? 93 SER A C 1 ATOM 746 O O . SER A 1 112 ? 1.335 26.159 -19.666 1.00 24.10 ? 93 SER A O 1 ATOM 747 C CB . SER A 1 112 ? -0.350 23.974 -21.423 1.00 22.27 ? 93 SER A CB 1 ATOM 748 O OG . SER A 1 112 ? -0.976 24.159 -20.164 1.00 23.09 ? 93 SER A OG 1 ATOM 749 N N . LYS A 1 113 ? 0.714 26.960 -21.660 1.00 24.55 ? 94 LYS A N 1 ATOM 750 C CA . LYS A 1 113 ? 0.674 28.318 -21.106 1.00 26.41 ? 94 LYS A CA 1 ATOM 751 C C . LYS A 1 113 ? -0.590 28.538 -20.294 1.00 23.67 ? 94 LYS A C 1 ATOM 752 O O . LYS A 1 113 ? -1.606 27.882 -20.536 1.00 26.06 ? 94 LYS A O 1 ATOM 753 C CB . LYS A 1 113 ? 0.845 29.396 -22.190 1.00 32.40 ? 94 LYS A CB 1 ATOM 754 C CG . LYS A 1 113 ? -0.225 29.438 -23.255 1.00 39.38 ? 94 LYS A CG 1 ATOM 755 C CD . LYS A 1 113 ? 0.233 30.345 -24.411 1.00 47.18 ? 94 LYS A CD 1 ATOM 756 C CE . LYS A 1 113 ? 0.701 31.713 -23.896 1.00 50.27 ? 94 LYS A CE 1 ATOM 757 N NZ . LYS A 1 113 ? 0.818 32.748 -24.973 1.00 44.43 ? 94 LYS A NZ 1 ATOM 758 N N . PRO A 1 114 ? -0.536 29.456 -19.316 1.00 24.85 ? 95 PRO A N 1 ATOM 759 C CA . PRO A 1 114 ? -1.729 29.646 -18.479 1.00 20.13 ? 95 PRO A CA 1 ATOM 760 C C . PRO A 1 114 ? -2.894 30.119 -19.333 1.00 23.48 ? 95 PRO A C 1 ATOM 761 O O . PRO A 1 114 ? -2.697 31.015 -20.154 1.00 32.43 ? 95 PRO A O 1 ATOM 762 C CB . PRO A 1 114 ? -1.319 30.777 -17.538 1.00 18.71 ? 95 PRO A CB 1 ATOM 763 C CG . PRO A 1 114 ? 0.173 30.855 -17.632 1.00 20.92 ? 95 PRO A CG 1 ATOM 764 C CD . PRO A 1 114 ? 0.538 30.415 -18.993 1.00 17.13 ? 95 PRO A CD 1 ATOM 765 N N . GLU A 1 115 ? -4.070 29.524 -19.158 1.00 21.40 ? 96 GLU A N 1 ATOM 766 C CA . GLU A 1 115 ? -5.288 30.002 -19.808 1.00 21.00 ? 96 GLU A CA 1 ATOM 767 C C . GLU A 1 115 ? -6.079 30.788 -18.777 1.00 24.56 ? 96 GLU A C 1 ATOM 768 O O . GLU A 1 115 ? -6.626 30.192 -17.832 1.00 21.23 ? 96 GLU A O 1 ATOM 769 C CB . GLU A 1 115 ? -6.125 28.831 -20.288 1.00 22.82 ? 96 GLU A CB 1 ATOM 770 C CG . GLU A 1 115 ? -7.351 29.181 -21.098 1.00 21.79 ? 96 GLU A CG 1 ATOM 771 C CD . GLU A 1 115 ? -8.077 27.916 -21.574 1.00 58.35 ? 96 GLU A CD 1 ATOM 772 O OE1 . GLU A 1 115 ? -7.444 26.821 -21.537 1.00 63.14 ? 96 GLU A OE1 1 ATOM 773 O OE2 . GLU A 1 115 ? -9.278 28.010 -21.967 1.00 66.51 ? 96 GLU A OE2 1 ATOM 774 N N . VAL A 1 116 ? -6.132 32.117 -18.942 1.00 22.65 ? 97 VAL A N 1 ATOM 775 C CA . VAL A 1 116 ? -6.791 32.989 -17.959 1.00 18.33 ? 97 VAL A CA 1 ATOM 776 C C . VAL A 1 116 ? -8.303 33.074 -18.170 1.00 16.97 ? 97 VAL A C 1 ATOM 777 O O . VAL A 1 116 ? -8.772 33.569 -19.183 1.00 25.71 ? 97 VAL A O 1 ATOM 778 C CB . VAL A 1 116 ? -6.173 34.394 -17.949 1.00 17.01 ? 97 VAL A CB 1 ATOM 779 C CG1 . VAL A 1 116 ? -6.800 35.242 -16.858 1.00 14.31 ? 97 VAL A CG1 1 ATOM 780 C CG2 . VAL A 1 116 ? -4.690 34.289 -17.752 1.00 18.26 ? 97 VAL A CG2 1 ATOM 781 N N . LEU A 1 117 ? -9.061 32.591 -17.198 1.00 17.12 ? 98 LEU A N 1 ATOM 782 C CA . LEU A 1 117 ? -10.502 32.435 -17.355 1.00 19.06 ? 98 LEU A CA 1 ATOM 783 C C . LEU A 1 117 ? -11.302 33.697 -17.010 1.00 21.90 ? 98 LEU A C 1 ATOM 784 O O . LEU A 1 117 ? -12.434 33.877 -17.467 1.00 29.07 ? 98 LEU A O 1 ATOM 785 C CB . LEU A 1 117 ? -10.995 31.238 -16.522 1.00 20.56 ? 98 LEU A CB 1 ATOM 786 C CG . LEU A 1 117 ? -10.408 29.852 -16.863 1.00 22.74 ? 98 LEU A CG 1 ATOM 787 C CD1 . LEU A 1 117 ? -10.984 28.774 -15.961 1.00 21.54 ? 98 LEU A CD1 1 ATOM 788 C CD2 . LEU A 1 117 ? -10.590 29.444 -18.322 1.00 15.76 ? 98 LEU A CD2 1 ATOM 789 N N . THR A 1 118 ? -10.700 34.584 -16.233 1.00 18.04 ? 99 THR A N 1 ATOM 790 C CA . THR A 1 118 ? -11.431 35.707 -15.675 1.00 19.71 ? 99 THR A CA 1 ATOM 791 C C . THR A 1 118 ? -10.975 37.019 -16.264 1.00 17.01 ? 99 THR A C 1 ATOM 792 O O . THR A 1 118 ? -9.930 37.052 -16.910 1.00 19.00 ? 99 THR A O 1 ATOM 793 C CB . THR A 1 118 ? -11.243 35.730 -14.161 1.00 22.21 ? 99 THR A CB 1 ATOM 794 O OG1 . THR A 1 118 ? -9.846 35.601 -13.865 1.00 16.05 ? 99 THR A OG1 1 ATOM 795 C CG2 . THR A 1 118 ? -12.034 34.565 -13.515 1.00 21.62 ? 99 THR A CG2 1 ATOM 796 N N . PRO A 1 119 ? -11.760 38.101 -16.054 1.00 18.53 ? 100 PRO A N 1 ATOM 797 C CA . PRO A 1 119 ? -11.359 39.473 -16.421 1.00 18.07 ? 100 PRO A CA 1 ATOM 798 C C . PRO A 1 119 ? -10.007 39.839 -15.802 1.00 24.69 ? 100 PRO A C 1 ATOM 799 O O . PRO A 1 119 ? -9.761 39.513 -14.629 1.00 26.68 ? 100 PRO A O 1 ATOM 800 C CB . PRO A 1 119 ? -12.441 40.336 -15.777 1.00 17.12 ? 100 PRO A CB 1 ATOM 801 C CG . PRO A 1 119 ? -13.652 39.475 -15.775 1.00 19.79 ? 100 PRO A CG 1 ATOM 802 C CD . PRO A 1 119 ? -13.163 38.046 -15.597 1.00 19.48 ? 100 PRO A CD 1 ATOM 803 N N . GLN A 1 120 ? -9.148 40.515 -16.561 1.00 21.34 ? 101 GLN A N 1 ATOM 804 C CA . GLN A 1 120 ? -7.808 40.801 -16.070 1.00 16.60 ? 101 GLN A CA 1 ATOM 805 C C . GLN A 1 120 ? -7.694 42.128 -15.316 1.00 15.93 ? 101 GLN A C 1 ATOM 806 O O . GLN A 1 120 ? -7.023 43.060 -15.765 1.00 19.31 ? 101 GLN A O 1 ATOM 807 C CB . GLN A 1 120 ? -6.795 40.657 -17.203 1.00 15.12 ? 101 GLN A CB 1 ATOM 808 C CG . GLN A 1 120 ? -6.653 39.201 -17.630 1.00 17.65 ? 101 GLN A CG 1 ATOM 809 C CD . GLN A 1 120 ? -5.723 38.975 -18.821 1.00 22.15 ? 101 GLN A CD 1 ATOM 810 O OE1 . GLN A 1 120 ? -4.693 39.633 -18.961 1.00 42.37 ? 101 GLN A OE1 1 ATOM 811 N NE2 . GLN A 1 120 ? -6.080 38.019 -19.677 1.00 23.44 ? 101 GLN A NE2 1 ATOM 812 N N . LEU A 1 121 ? -8.358 42.196 -14.161 1.00 14.93 ? 102 LEU A N 1 ATOM 813 C CA . LEU A 1 121 ? -8.335 43.391 -13.314 1.00 13.01 ? 102 LEU A CA 1 ATOM 814 C C . LEU A 1 121 ? -7.662 43.106 -11.984 1.00 13.72 ? 102 LEU A C 1 ATOM 815 O O . LEU A 1 121 ? -7.804 42.019 -11.429 1.00 20.31 ? 102 LEU A O 1 ATOM 816 C CB . LEU A 1 121 ? -9.757 43.876 -13.037 1.00 17.24 ? 102 LEU A CB 1 ATOM 817 C CG . LEU A 1 121 ? -10.573 44.252 -14.269 1.00 16.33 ? 102 LEU A CG 1 ATOM 818 C CD1 . LEU A 1 121 ? -11.978 44.675 -13.888 1.00 11.44 ? 102 LEU A CD1 1 ATOM 819 C CD2 . LEU A 1 121 ? -9.853 45.341 -15.021 1.00 12.99 ? 102 LEU A CD2 1 ATOM 820 N N . ALA A 1 122 ? -6.937 44.091 -11.469 1.00 12.59 ? 103 ALA A N 1 ATOM 821 C CA . ALA A 1 122 ? -6.378 44.017 -10.127 1.00 14.57 ? 103 ALA A CA 1 ATOM 822 C C . ALA A 1 122 ? -7.109 44.946 -9.146 1.00 14.83 ? 103 ALA A C 1 ATOM 823 O O . ALA A 1 122 ? -7.623 46.001 -9.517 1.00 18.79 ? 103 ALA A O 1 ATOM 824 C CB . ALA A 1 122 ? -4.890 44.345 -10.161 1.00 13.88 ? 103 ALA A CB 1 ATOM 825 N N . HIS A 1 123 ? -7.127 44.560 -7.884 1.00 15.35 ? 104 HIS A N 1 ATOM 826 C CA . HIS A 1 123 ? -7.732 45.366 -6.835 1.00 17.53 ? 104 HIS A CA 1 ATOM 827 C C . HIS A 1 123 ? -6.641 46.230 -6.213 1.00 15.89 ? 104 HIS A C 1 ATOM 828 O O . HIS A 1 123 ? -5.571 45.721 -5.874 1.00 18.02 ? 104 HIS A O 1 ATOM 829 C CB . HIS A 1 123 ? -8.324 44.421 -5.797 1.00 26.03 ? 104 HIS A CB 1 ATOM 830 C CG . HIS A 1 123 ? -9.257 45.078 -4.839 1.00 29.37 ? 104 HIS A CG 1 ATOM 831 N ND1 . HIS A 1 123 ? -8.905 45.350 -3.536 1.00 31.30 ? 104 HIS A ND1 1 ATOM 832 C CD2 . HIS A 1 123 ? -10.537 45.495 -4.985 1.00 33.73 ? 104 HIS A CD2 1 ATOM 833 C CE1 . HIS A 1 123 ? -9.929 45.917 -2.919 1.00 37.75 ? 104 HIS A CE1 1 ATOM 834 N NE2 . HIS A 1 123 ? -10.929 46.023 -3.775 1.00 35.83 ? 104 HIS A NE2 1 ATOM 835 N N . VAL A 1 124 ? -6.885 47.535 -6.094 1.00 18.02 ? 105 VAL A N 1 ATOM 836 C CA . VAL A 1 124 ? -5.883 48.462 -5.543 1.00 16.74 ? 105 VAL A CA 1 ATOM 837 C C . VAL A 1 124 ? -6.488 49.244 -4.392 1.00 19.34 ? 105 VAL A C 1 ATOM 838 O O . VAL A 1 124 ? -7.550 49.839 -4.536 1.00 20.64 ? 105 VAL A O 1 ATOM 839 C CB . VAL A 1 124 ? -5.386 49.481 -6.581 1.00 12.66 ? 105 VAL A CB 1 ATOM 840 C CG1 . VAL A 1 124 ? -4.251 50.293 -6.004 1.00 12.95 ? 105 VAL A CG1 1 ATOM 841 C CG2 . VAL A 1 124 ? -4.936 48.802 -7.854 1.00 12.05 ? 105 VAL A CG2 1 ATOM 842 N N . VAL A 1 125 ? -5.811 49.233 -3.250 1.00 15.98 ? 106 VAL A N 1 ATOM 843 C CA . VAL A 1 125 ? -6.283 49.928 -2.057 1.00 18.21 ? 106 VAL A CA 1 ATOM 844 C C . VAL A 1 125 ? -5.468 51.224 -1.920 1.00 21.70 ? 106 VAL A C 1 ATOM 845 O O . VAL A 1 125 ? -4.325 51.265 -2.363 1.00 24.79 ? 106 VAL A O 1 ATOM 846 C CB . VAL A 1 125 ? -6.124 49.016 -0.808 1.00 18.87 ? 106 VAL A CB 1 ATOM 847 C CG1 . VAL A 1 125 ? -6.397 49.786 0.456 1.00 24.79 ? 106 VAL A CG1 1 ATOM 848 C CG2 . VAL A 1 125 ? -7.042 47.807 -0.908 1.00 13.57 ? 106 VAL A CG2 1 ATOM 849 N N . SER A 1 126 ? -6.040 52.273 -1.326 1.00 22.03 ? 107 SER A N 1 ATOM 850 C CA . SER A 1 126 ? -5.381 53.580 -1.259 1.00 19.33 ? 107 SER A CA 1 ATOM 851 C C . SER A 1 126 ? -3.969 53.594 -0.653 1.00 22.57 ? 107 SER A C 1 ATOM 852 O O . SER A 1 126 ? -3.192 54.507 -0.931 1.00 23.41 ? 107 SER A O 1 ATOM 853 C CB . SER A 1 126 ? -6.261 54.578 -0.529 1.00 21.34 ? 107 SER A CB 1 ATOM 854 O OG . SER A 1 126 ? -6.573 54.084 0.747 1.00 27.90 ? 107 SER A OG 1 ATOM 855 N N . ASP A 1 127 ? -3.626 52.603 0.168 1.00 20.89 ? 108 ASP A N 1 ATOM 856 C CA . ASP A 1 127 ? -2.265 52.549 0.713 1.00 21.23 ? 108 ASP A CA 1 ATOM 857 C C . ASP A 1 127 ? -1.211 52.072 -0.287 1.00 23.07 ? 108 ASP A C 1 ATOM 858 O O . ASP A 1 127 ? -0.015 52.231 -0.057 1.00 34.34 ? 108 ASP A O 1 ATOM 859 C CB . ASP A 1 127 ? -2.179 51.728 2.014 1.00 22.37 ? 108 ASP A CB 1 ATOM 860 C CG . ASP A 1 127 ? -2.643 50.271 1.847 1.00 42.88 ? 108 ASP A CG 1 ATOM 861 O OD1 . ASP A 1 127 ? -2.807 49.792 0.688 1.00 40.18 ? 108 ASP A OD1 1 ATOM 862 O OD2 . ASP A 1 127 ? -2.830 49.594 2.896 1.00 44.51 ? 108 ASP A OD2 1 ATOM 863 N N . GLY A 1 128 ? -1.656 51.485 -1.391 1.00 22.49 ? 109 GLY A N 1 ATOM 864 C CA . GLY A 1 128 ? -0.746 50.968 -2.390 1.00 24.13 ? 109 GLY A CA 1 ATOM 865 C C . GLY A 1 128 ? -0.692 49.453 -2.428 1.00 24.42 ? 109 GLY A C 1 ATOM 866 O O . GLY A 1 128 ? 0.175 48.886 -3.098 1.00 23.17 ? 109 GLY A O 1 ATOM 867 N N . GLU A 1 129 ? -1.609 48.797 -1.716 1.00 23.29 ? 110 GLU A N 1 ATOM 868 C CA . GLU A 1 129 ? -1.697 47.325 -1.726 1.00 23.01 ? 110 GLU A CA 1 ATOM 869 C C . GLU A 1 129 ? -2.437 46.805 -2.950 1.00 19.82 ? 110 GLU A C 1 ATOM 870 O O . GLU A 1 129 ? -3.555 47.228 -3.263 1.00 19.68 ? 110 GLU A O 1 ATOM 871 C CB . GLU A 1 129 ? -2.373 46.807 -0.458 1.00 25.14 ? 110 GLU A CB 1 ATOM 872 C CG . GLU A 1 129 ? -1.435 46.651 0.713 1.00 37.61 ? 110 GLU A CG 1 ATOM 873 C CD . GLU A 1 129 ? -0.513 45.449 0.549 1.00 54.87 ? 110 GLU A CD 1 ATOM 874 O OE1 . GLU A 1 129 ? -1.024 44.353 0.195 1.00 58.40 ? 110 GLU A OE1 1 ATOM 875 O OE2 . GLU A 1 129 ? 0.718 45.605 0.763 1.00 61.07 ? 110 GLU A OE2 1 ATOM 876 N N . VAL A 1 130 ? -1.811 45.887 -3.656 1.00 17.23 ? 111 VAL A N 1 ATOM 877 C CA . VAL A 1 130 ? -2.421 45.366 -4.861 1.00 18.38 ? 111 VAL A CA 1 ATOM 878 C C . VAL A 1 130 ? -2.719 43.883 -4.684 1.00 19.77 ? 111 VAL A C 1 ATOM 879 O O . VAL A 1 130 ? -1.902 43.134 -4.131 1.00 22.03 ? 111 VAL A O 1 ATOM 880 C CB . VAL A 1 130 ? -1.493 45.578 -6.073 1.00 19.21 ? 111 VAL A CB 1 ATOM 881 C CG1 . VAL A 1 130 ? -2.182 45.144 -7.393 1.00 16.14 ? 111 VAL A CG1 1 ATOM 882 C CG2 . VAL A 1 130 ? -1.052 47.010 -6.140 1.00 11.11 ? 111 VAL A CG2 1 ATOM 883 N N . GLN A 1 131 ? -3.886 43.453 -5.152 1.00 21.20 ? 112 GLN A N 1 ATOM 884 C CA . GLN A 1 131 ? -4.184 42.021 -5.216 1.00 20.38 ? 112 GLN A CA 1 ATOM 885 C C . GLN A 1 131 ? -4.691 41.618 -6.602 1.00 19.05 ? 112 GLN A C 1 ATOM 886 O O . GLN A 1 131 ? -5.626 42.214 -7.129 1.00 19.01 ? 112 GLN A O 1 ATOM 887 C CB . GLN A 1 131 ? -5.197 41.622 -4.152 1.00 19.74 ? 112 GLN A CB 1 ATOM 888 C CG . GLN A 1 131 ? -5.503 40.143 -4.158 1.00 28.43 ? 112 GLN A CG 1 ATOM 889 C CD . GLN A 1 131 ? -6.463 39.748 -3.062 1.00 35.99 ? 112 GLN A CD 1 ATOM 890 O OE1 . GLN A 1 131 ? -6.364 40.237 -1.935 1.00 40.70 ? 112 GLN A OE1 1 ATOM 891 N NE2 . GLN A 1 131 ? -7.410 38.858 -3.386 1.00 46.75 ? 112 GLN A NE2 1 ATOM 892 N N . TYR A 1 132 ? -4.068 40.609 -7.193 1.00 15.96 ? 113 TYR A N 1 ATOM 893 C CA . TYR A 1 132 ? -4.493 40.125 -8.494 1.00 15.53 ? 113 TYR A CA 1 ATOM 894 C C . TYR A 1 132 ? -4.740 38.623 -8.383 1.00 21.33 ? 113 TYR A C 1 ATOM 895 O O . TYR A 1 132 ? -3.819 37.852 -8.096 1.00 21.28 ? 113 TYR A O 1 ATOM 896 C CB . TYR A 1 132 ? -3.430 40.453 -9.552 1.00 12.75 ? 113 TYR A CB 1 ATOM 897 C CG . TYR A 1 132 ? -3.727 39.912 -10.923 1.00 13.20 ? 113 TYR A CG 1 ATOM 898 C CD1 . TYR A 1 132 ? -5.001 40.013 -11.472 1.00 17.49 ? 113 TYR A CD1 1 ATOM 899 C CD2 . TYR A 1 132 ? -2.741 39.301 -11.676 1.00 10.08 ? 113 TYR A CD2 1 ATOM 900 C CE1 . TYR A 1 132 ? -5.283 39.505 -12.747 1.00 17.59 ? 113 TYR A CE1 1 ATOM 901 C CE2 . TYR A 1 132 ? -3.014 38.788 -12.940 1.00 12.35 ? 113 TYR A CE2 1 ATOM 902 C CZ . TYR A 1 132 ? -4.283 38.887 -13.474 1.00 13.01 ? 113 TYR A CZ 1 ATOM 903 O OH . TYR A 1 132 ? -4.539 38.383 -14.743 1.00 15.03 ? 113 TYR A OH 1 ATOM 904 N N . THR A 1 133 ? -5.987 38.214 -8.612 1.00 20.12 ? 114 THR A N 1 ATOM 905 C CA . THR A 1 133 ? -6.391 36.838 -8.400 1.00 15.49 ? 114 THR A CA 1 ATOM 906 C C . THR A 1 133 ? -7.121 36.295 -9.622 1.00 18.44 ? 114 THR A C 1 ATOM 907 O O . THR A 1 133 ? -8.351 36.208 -9.650 1.00 21.66 ? 114 THR A O 1 ATOM 908 C CB . THR A 1 133 ? -7.300 36.719 -7.164 1.00 21.73 ? 114 THR A CB 1 ATOM 909 O OG1 . THR A 1 133 ? -6.744 37.474 -6.075 1.00 22.92 ? 114 THR A OG1 1 ATOM 910 C CG2 . THR A 1 133 ? -7.485 35.252 -6.754 1.00 20.54 ? 114 THR A CG2 1 ATOM 911 N N . PRO A 1 134 ? -6.362 35.920 -10.657 1.00 18.91 ? 115 PRO A N 1 ATOM 912 C CA . PRO A 1 134 ? -7.040 35.338 -11.834 1.00 17.86 ? 115 PRO A CA 1 ATOM 913 C C . PRO A 1 134 ? -7.383 33.867 -11.616 1.00 23.63 ? 115 PRO A C 1 ATOM 914 O O . PRO A 1 134 ? -6.696 33.173 -10.845 1.00 21.54 ? 115 PRO A O 1 ATOM 915 C CB . PRO A 1 134 ? -5.981 35.452 -12.937 1.00 13.39 ? 115 PRO A CB 1 ATOM 916 C CG . PRO A 1 134 ? -4.656 35.442 -12.172 1.00 11.99 ? 115 PRO A CG 1 ATOM 917 C CD . PRO A 1 134 ? -4.911 36.117 -10.857 1.00 12.66 ? 115 PRO A CD 1 ATOM 918 N N . SER A 1 135 ? -8.427 33.387 -12.290 1.00 26.68 ? 116 SER A N 1 ATOM 919 C CA . SER A 1 135 ? -8.688 31.950 -12.330 1.00 18.57 ? 116 SER A CA 1 ATOM 920 C C . SER A 1 135 ? -7.965 31.377 -13.544 1.00 21.38 ? 116 SER A C 1 ATOM 921 O O . SER A 1 135 ? -8.116 31.879 -14.661 1.00 21.16 ? 116 SER A O 1 ATOM 922 C CB . SER A 1 135 ? -10.175 31.670 -12.438 1.00 17.19 ? 116 SER A CB 1 ATOM 923 O OG . SER A 1 135 ? -10.412 30.277 -12.403 1.00 24.62 ? 116 SER A OG 1 ATOM 924 N N . ILE A 1 136 ? -7.172 30.330 -13.316 1.00 20.86 ? 117 ILE A N 1 ATOM 925 C CA . ILE A 1 136 ? -6.307 29.762 -14.352 1.00 18.42 ? 117 ILE A CA 1 ATOM 926 C C . ILE A 1 136 ? -6.497 28.247 -14.574 1.00 23.33 ? 117 ILE A C 1 ATOM 927 O O . ILE A 1 136 ? -6.501 27.451 -13.626 1.00 23.57 ? 117 ILE A O 1 ATOM 928 C CB . ILE A 1 136 ? -4.828 30.045 -14.022 1.00 14.09 ? 117 ILE A CB 1 ATOM 929 C CG1 . ILE A 1 136 ? -4.558 31.552 -14.063 1.00 19.72 ? 117 ILE A CG1 1 ATOM 930 C CG2 . ILE A 1 136 ? -3.906 29.326 -14.983 1.00 17.35 ? 117 ILE A CG2 1 ATOM 931 C CD1 . ILE A 1 136 ? -3.168 31.942 -13.597 1.00 18.37 ? 117 ILE A CD1 1 ATOM 932 N N . ARG A 1 137 ? -6.655 27.848 -15.833 1.00 22.53 ? 118 ARG A N 1 ATOM 933 C CA . ARG A 1 137 ? -6.580 26.436 -16.182 1.00 16.54 ? 118 ARG A CA 1 ATOM 934 C C . ARG A 1 137 ? -5.212 26.167 -16.800 1.00 15.94 ? 118 ARG A C 1 ATOM 935 O O . ARG A 1 137 ? -4.845 26.796 -17.780 1.00 16.21 ? 118 ARG A O 1 ATOM 936 C CB . ARG A 1 137 ? -7.691 26.051 -17.164 1.00 19.12 ? 118 ARG A CB 1 ATOM 937 C CG . ARG A 1 137 ? -7.487 24.696 -17.786 1.00 26.05 ? 118 ARG A CG 1 ATOM 938 C CD . ARG A 1 137 ? -8.770 24.109 -18.326 1.00 31.16 ? 118 ARG A CD 1 ATOM 939 N NE . ARG A 1 137 ? -8.583 22.729 -18.777 1.00 32.47 ? 118 ARG A NE 1 ATOM 940 C CZ . ARG A 1 137 ? -9.567 21.950 -19.212 1.00 31.73 ? 118 ARG A CZ 1 ATOM 941 N NH1 . ARG A 1 137 ? -10.809 22.410 -19.239 1.00 32.32 ? 118 ARG A NH1 1 ATOM 942 N NH2 . ARG A 1 137 ? -9.313 20.708 -19.600 1.00 39.85 ? 118 ARG A NH2 1 ATOM 943 N N . GLN A 1 138 ? -4.460 25.236 -16.224 1.00 17.27 ? 119 GLN A N 1 ATOM 944 C CA . GLN A 1 138 ? -3.128 24.902 -16.733 1.00 21.74 ? 119 GLN A CA 1 ATOM 945 C C . GLN A 1 138 ? -2.802 23.397 -16.637 1.00 22.06 ? 119 GLN A C 1 ATOM 946 O O . GLN A 1 138 ? -3.270 22.714 -15.728 1.00 22.40 ? 119 GLN A O 1 ATOM 947 C CB . GLN A 1 138 ? -2.068 25.729 -15.996 1.00 19.76 ? 119 GLN A CB 1 ATOM 948 C CG . GLN A 1 138 ? -0.739 25.831 -16.730 1.00 23.34 ? 119 GLN A CG 1 ATOM 949 C CD . GLN A 1 138 ? 0.096 27.020 -16.245 1.00 28.83 ? 119 GLN A CD 1 ATOM 950 O OE1 . GLN A 1 138 ? -0.120 27.541 -15.147 1.00 34.15 ? 119 GLN A OE1 1 ATOM 951 N NE2 . GLN A 1 138 ? 1.043 27.462 -17.070 1.00 27.65 ? 119 GLN A NE2 1 ATOM 952 N N . ARG A 1 139 ? -1.995 22.895 -17.571 1.00 21.78 ? 120 ARG A N 1 ATOM 953 C CA . ARG A 1 139 ? -1.538 21.505 -17.547 1.00 21.36 ? 120 ARG A CA 1 ATOM 954 C C . ARG A 1 139 ? -0.123 21.387 -16.923 1.00 20.29 ? 120 ARG A C 1 ATOM 955 O O . ARG A 1 139 ? 0.776 22.170 -17.236 1.00 22.03 ? 120 ARG A O 1 ATOM 956 C CB . ARG A 1 139 ? -1.592 20.906 -18.963 1.00 18.81 ? 120 ARG A CB 1 ATOM 957 C CG . ARG A 1 139 ? -1.557 19.393 -18.978 1.00 29.09 ? 120 ARG A CG 1 ATOM 958 C CD . ARG A 1 139 ? -2.151 18.736 -20.235 1.00 35.17 ? 120 ARG A CD 1 ATOM 959 N NE . ARG A 1 139 ? -2.154 17.271 -20.098 1.00 35.54 ? 120 ARG A NE 1 ATOM 960 C CZ . ARG A 1 139 ? -3.149 16.558 -19.558 1.00 40.69 ? 120 ARG A CZ 1 ATOM 961 N NH1 . ARG A 1 139 ? -4.250 17.150 -19.113 1.00 40.89 ? 120 ARG A NH1 1 ATOM 962 N NH2 . ARG A 1 139 ? -3.051 15.242 -19.460 1.00 43.17 ? 120 ARG A NH2 1 ATOM 963 N N . PHE A 1 140 ? 0.065 20.429 -16.021 1.00 20.38 ? 121 PHE A N 1 ATOM 964 C CA . PHE A 1 140 ? 1.370 20.228 -15.368 1.00 27.39 ? 121 PHE A CA 1 ATOM 965 C C . PHE A 1 140 ? 1.973 18.829 -15.518 1.00 25.17 ? 121 PHE A C 1 ATOM 966 O O . PHE A 1 140 ? 1.286 17.853 -15.814 1.00 26.85 ? 121 PHE A O 1 ATOM 967 C CB . PHE A 1 140 ? 1.297 20.529 -13.872 1.00 21.58 ? 121 PHE A CB 1 ATOM 968 C CG . PHE A 1 140 ? 0.885 21.922 -13.562 1.00 24.62 ? 121 PHE A CG 1 ATOM 969 C CD1 . PHE A 1 140 ? -0.464 22.252 -13.485 1.00 25.12 ? 121 PHE A CD1 1 ATOM 970 C CD2 . PHE A 1 140 ? 1.837 22.910 -13.339 1.00 20.79 ? 121 PHE A CD2 1 ATOM 971 C CE1 . PHE A 1 140 ? -0.866 23.545 -13.194 1.00 24.55 ? 121 PHE A CE1 1 ATOM 972 C CE2 . PHE A 1 140 ? 1.444 24.213 -13.050 1.00 23.83 ? 121 PHE A CE2 1 ATOM 973 C CZ . PHE A 1 140 ? 0.087 24.531 -12.979 1.00 25.21 ? 121 PHE A CZ 1 ATOM 974 N N . SER A 1 141 ? 3.272 18.748 -15.279 1.00 25.11 ? 122 SER A N 1 ATOM 975 C CA . SER A 1 141 ? 3.979 17.482 -15.265 1.00 27.41 ? 122 SER A CA 1 ATOM 976 C C . SER A 1 141 ? 4.368 17.215 -13.817 1.00 28.13 ? 122 SER A C 1 ATOM 977 O O . SER A 1 141 ? 5.147 17.963 -13.226 1.00 34.98 ? 122 SER A O 1 ATOM 978 C CB . SER A 1 141 ? 5.223 17.570 -16.157 1.00 21.73 ? 122 SER A CB 1 ATOM 979 O OG . SER A 1 141 ? 6.194 16.613 -15.785 1.00 19.38 ? 122 SER A OG 1 ATOM 980 N N . CYS A 1 142 ? 3.813 16.159 -13.241 1.00 30.38 ? 123 CYS A N 1 ATOM 981 C CA . CYS A 1 142 ? 4.088 15.819 -11.846 1.00 40.50 ? 123 CYS A CA 1 ATOM 982 C C . CYS A 1 142 ? 3.807 14.338 -11.520 1.00 35.40 ? 123 CYS A C 1 ATOM 983 O O . CYS A 1 142 ? 3.381 13.563 -12.382 1.00 25.69 ? 123 CYS A O 1 ATOM 984 C CB . CYS A 1 142 ? 3.284 16.736 -10.924 1.00 39.42 ? 123 CYS A CB 1 ATOM 985 S SG . CYS A 1 142 ? 1.506 16.711 -11.282 1.00 65.60 ? 123 CYS A SG 1 ATOM 986 N N . ASP A 1 143 ? 4.043 13.960 -10.266 1.00 37.41 ? 124 ASP A N 1 ATOM 987 C CA . ASP A 1 143 ? 3.884 12.568 -9.842 1.00 34.35 ? 124 ASP A CA 1 ATOM 988 C C . ASP A 1 143 ? 2.426 12.213 -9.590 1.00 30.72 ? 124 ASP A C 1 ATOM 989 O O . ASP A 1 143 ? 1.800 12.713 -8.656 1.00 38.94 ? 124 ASP A O 1 ATOM 990 C CB . ASP A 1 143 ? 4.720 12.282 -8.596 1.00 35.50 ? 124 ASP A CB 1 ATOM 991 C CG . ASP A 1 143 ? 4.923 10.805 -8.364 1.00 37.49 ? 124 ASP A CG 1 ATOM 992 O OD1 . ASP A 1 143 ? 4.575 10.002 -9.263 1.00 34.11 ? 124 ASP A OD1 1 ATOM 993 O OD2 . ASP A 1 143 ? 5.450 10.452 -7.288 1.00 48.14 ? 124 ASP A OD2 1 ATOM 994 N N . VAL A 1 144 ? 1.896 11.335 -10.429 1.00 32.68 ? 125 VAL A N 1 ATOM 995 C CA . VAL A 1 144 ? 0.469 11.017 -10.436 1.00 30.40 ? 125 VAL A CA 1 ATOM 996 C C . VAL A 1 144 ? 0.206 9.619 -9.858 1.00 33.98 ? 125 VAL A C 1 ATOM 997 O O . VAL A 1 144 ? -0.933 9.267 -9.551 1.00 33.61 ? 125 VAL A O 1 ATOM 998 C CB . VAL A 1 144 ? -0.080 11.123 -11.883 1.00 36.23 ? 125 VAL A CB 1 ATOM 999 C CG1 . VAL A 1 144 ? -1.554 10.851 -11.938 1.00 31.87 ? 125 VAL A CG1 1 ATOM 1000 C CG2 . VAL A 1 144 ? 0.208 12.498 -12.474 1.00 36.05 ? 125 VAL A CG2 1 ATOM 1001 N N . SER A 1 145 ? 1.276 8.839 -9.698 1.00 34.56 ? 126 SER A N 1 ATOM 1002 C CA . SER A 1 145 ? 1.191 7.478 -9.176 1.00 32.33 ? 126 SER A CA 1 ATOM 1003 C C . SER A 1 145 ? 0.423 7.396 -7.847 1.00 35.68 ? 126 SER A C 1 ATOM 1004 O O . SER A 1 145 ? 0.680 8.164 -6.910 1.00 35.79 ? 126 SER A O 1 ATOM 1005 C CB . SER A 1 145 ? 2.591 6.900 -8.996 1.00 30.52 ? 126 SER A CB 1 ATOM 1006 O OG . SER A 1 145 ? 3.323 7.678 -8.069 1.00 39.96 ? 126 SER A OG 1 ATOM 1007 N N . GLY A 1 146 ? -0.529 6.469 -7.782 1.00 34.19 ? 127 GLY A N 1 ATOM 1008 C CA . GLY A 1 146 ? -1.276 6.227 -6.561 1.00 30.87 ? 127 GLY A CA 1 ATOM 1009 C C . GLY A 1 146 ? -2.531 7.061 -6.509 1.00 38.58 ? 127 GLY A C 1 ATOM 1010 O O . GLY A 1 146 ? -3.135 7.234 -5.447 1.00 41.32 ? 127 GLY A O 1 ATOM 1011 N N . VAL A 1 147 ? -2.924 7.591 -7.663 1.00 38.61 ? 128 VAL A N 1 ATOM 1012 C CA . VAL A 1 147 ? -4.096 8.460 -7.728 1.00 37.71 ? 128 VAL A CA 1 ATOM 1013 C C . VAL A 1 147 ? -5.359 7.641 -7.462 1.00 32.22 ? 128 VAL A C 1 ATOM 1014 O O . VAL A 1 147 ? -6.362 8.161 -6.966 1.00 33.53 ? 128 VAL A O 1 ATOM 1015 C CB . VAL A 1 147 ? -4.169 9.221 -9.081 1.00 31.46 ? 128 VAL A CB 1 ATOM 1016 C CG1 . VAL A 1 147 ? -4.229 8.245 -10.230 1.00 31.25 ? 128 VAL A CG1 1 ATOM 1017 C CG2 . VAL A 1 147 ? -5.350 10.192 -9.107 1.00 27.77 ? 128 VAL A CG2 1 ATOM 1018 N N . ASP A 1 148 ? -5.286 6.348 -7.764 1.00 37.63 ? 129 ASP A N 1 ATOM 1019 C CA . ASP A 1 148 ? -6.425 5.449 -7.567 1.00 44.79 ? 129 ASP A CA 1 ATOM 1020 C C . ASP A 1 148 ? -6.283 4.590 -6.299 1.00 34.58 ? 129 ASP A C 1 ATOM 1021 O O . ASP A 1 148 ? -6.699 3.449 -6.271 1.00 41.63 ? 129 ASP A O 1 ATOM 1022 C CB . ASP A 1 148 ? -6.625 4.577 -8.810 1.00 39.60 ? 129 ASP A CB 1 ATOM 1023 C CG . ASP A 1 148 ? -8.092 4.316 -9.101 1.00 48.69 ? 129 ASP A CG 1 ATOM 1024 O OD1 . ASP A 1 148 ? -8.845 4.067 -8.127 1.00 48.24 ? 129 ASP A OD1 1 ATOM 1025 O OD2 . ASP A 1 148 ? -8.489 4.373 -10.290 1.00 56.54 ? 129 ASP A OD2 1 ATOM 1026 N N . THR A 1 149 ? -5.717 5.187 -5.255 1.00 31.35 ? 130 THR A N 1 ATOM 1027 C CA . THR A 1 149 ? -5.324 4.524 -4.021 1.00 27.02 ? 130 THR A CA 1 ATOM 1028 C C . THR A 1 149 ? -5.903 5.316 -2.843 1.00 39.98 ? 130 THR A C 1 ATOM 1029 O O . THR A 1 149 ? -6.216 6.499 -2.973 1.00 46.23 ? 130 THR A O 1 ATOM 1030 C CB . THR A 1 149 ? -3.779 4.496 -3.942 1.00 34.10 ? 130 THR A CB 1 ATOM 1031 O OG1 . THR A 1 149 ? -3.279 3.576 -4.914 1.00 27.71 ? 130 THR A OG1 1 ATOM 1032 C CG2 . THR A 1 149 ? -3.248 4.102 -2.552 1.00 42.09 ? 130 THR A CG2 1 ATOM 1033 N N . GLU A 1 150 ? -6.058 4.683 -1.692 1.00 39.22 ? 131 GLU A N 1 ATOM 1034 C CA . GLU A 1 150 ? -6.623 5.371 -0.549 1.00 43.89 ? 131 GLU A CA 1 ATOM 1035 C C . GLU A 1 150 ? -5.730 6.521 -0.048 1.00 43.91 ? 131 GLU A C 1 ATOM 1036 O O . GLU A 1 150 ? -6.228 7.493 0.524 1.00 46.01 ? 131 GLU A O 1 ATOM 1037 C CB . GLU A 1 150 ? -6.901 4.362 0.562 1.00 48.12 ? 131 GLU A CB 1 ATOM 1038 C CG . GLU A 1 150 ? -7.834 4.852 1.640 1.00 60.29 ? 131 GLU A CG 1 ATOM 1039 C CD . GLU A 1 150 ? -7.703 4.044 2.917 1.00 74.65 ? 131 GLU A CD 1 ATOM 1040 O OE1 . GLU A 1 150 ? -6.562 3.688 3.284 1.00 79.93 ? 131 GLU A OE1 1 ATOM 1041 O OE2 . GLU A 1 150 ? -8.740 3.755 3.549 1.00 86.92 ? 131 GLU A OE2 1 ATOM 1042 N N . SER A 1 151 ? -4.420 6.420 -0.276 1.00 43.17 ? 132 SER A N 1 ATOM 1043 C CA . SER A 1 151 ? -3.466 7.454 0.177 1.00 49.47 ? 132 SER A CA 1 ATOM 1044 C C . SER A 1 151 ? -3.202 8.574 -0.854 1.00 43.62 ? 132 SER A C 1 ATOM 1045 O O . SER A 1 151 ? -2.627 9.622 -0.534 1.00 38.04 ? 132 SER A O 1 ATOM 1046 C CB . SER A 1 151 ? -2.143 6.810 0.616 1.00 52.39 ? 132 SER A CB 1 ATOM 1047 O OG . SER A 1 151 ? -1.624 5.964 -0.399 1.00 59.08 ? 132 SER A OG 1 ATOM 1048 N N . GLY A 1 152 ? -3.607 8.332 -2.095 1.00 39.66 ? 133 GLY A N 1 ATOM 1049 C CA . GLY A 1 152 ? -3.602 9.363 -3.116 1.00 40.70 ? 133 GLY A CA 1 ATOM 1050 C C . GLY A 1 152 ? -2.250 9.668 -3.740 1.00 41.96 ? 133 GLY A C 1 ATOM 1051 O O . GLY A 1 152 ? -1.218 9.144 -3.296 1.00 40.22 ? 133 GLY A O 1 ATOM 1052 N N . ALA A 1 153 ? -2.265 10.508 -4.782 1.00 35.09 ? 134 ALA A N 1 ATOM 1053 C CA . ALA A 1 153 ? -1.037 11.033 -5.384 1.00 35.03 ? 134 ALA A CA 1 ATOM 1054 C C . ALA A 1 153 ? -0.662 12.378 -4.754 1.00 33.70 ? 134 ALA A C 1 ATOM 1055 O O . ALA A 1 153 ? -1.525 13.105 -4.246 1.00 31.67 ? 134 ALA A O 1 ATOM 1056 C CB . ALA A 1 153 ? -1.198 11.177 -6.884 1.00 28.83 ? 134 ALA A CB 1 ATOM 1057 N N . THR A 1 154 ? 0.625 12.704 -4.784 1.00 33.98 ? 135 THR A N 1 ATOM 1058 C CA . THR A 1 154 ? 1.058 14.039 -4.389 1.00 31.97 ? 135 THR A CA 1 ATOM 1059 C C . THR A 1 154 ? 1.788 14.745 -5.528 1.00 34.10 ? 135 THR A C 1 ATOM 1060 O O . THR A 1 154 ? 2.931 14.419 -5.855 1.00 31.74 ? 135 THR A O 1 ATOM 1061 C CB . THR A 1 154 ? 1.932 14.034 -3.127 1.00 38.09 ? 135 THR A CB 1 ATOM 1062 O OG1 . THR A 1 154 ? 1.300 13.239 -2.117 1.00 48.81 ? 135 THR A OG1 1 ATOM 1063 C CG2 . THR A 1 154 ? 2.109 15.467 -2.594 1.00 40.11 ? 135 THR A CG2 1 ATOM 1064 N N . CYS A 1 155 ? 1.100 15.714 -6.120 1.00 31.45 ? 136 CYS A N 1 ATOM 1065 C CA . CYS A 1 155 ? 1.629 16.541 -7.191 1.00 33.07 ? 136 CYS A CA 1 ATOM 1066 C C . CYS A 1 155 ? 2.161 17.888 -6.643 1.00 35.92 ? 136 CYS A C 1 ATOM 1067 O O . CYS A 1 155 ? 1.453 18.582 -5.906 1.00 34.88 ? 136 CYS A O 1 ATOM 1068 C CB . CYS A 1 155 ? 0.507 16.795 -8.197 1.00 40.86 ? 136 CYS A CB 1 ATOM 1069 S SG . CYS A 1 155 ? 0.967 17.799 -9.632 1.00 82.15 ? 136 CYS A SG 1 ATOM 1070 N N . ARG A 1 156 ? 3.399 18.249 -6.992 1.00 35.43 ? 137 ARG A N 1 ATOM 1071 C CA . ARG A 1 156 ? 3.994 19.519 -6.560 1.00 28.03 ? 137 ARG A CA 1 ATOM 1072 C C . ARG A 1 156 ? 4.022 20.536 -7.714 1.00 30.18 ? 137 ARG A C 1 ATOM 1073 O O . ARG A 1 156 ? 4.370 20.202 -8.842 1.00 33.66 ? 137 ARG A O 1 ATOM 1074 C CB . ARG A 1 156 ? 5.417 19.325 -6.005 1.00 29.88 ? 137 ARG A CB 1 ATOM 1075 C CG . ARG A 1 156 ? 5.619 18.117 -5.069 1.00 29.73 ? 137 ARG A CG 1 ATOM 1076 C CD . ARG A 1 156 ? 7.066 18.027 -4.544 1.00 42.59 ? 137 ARG A CD 1 ATOM 1077 N NE . ARG A 1 156 ? 8.100 18.504 -5.486 1.00 55.11 ? 137 ARG A NE 1 ATOM 1078 C CZ . ARG A 1 156 ? 8.776 17.730 -6.342 1.00 51.89 ? 137 ARG A CZ 1 ATOM 1079 N NH1 . ARG A 1 156 ? 8.520 16.433 -6.405 1.00 43.03 ? 137 ARG A NH1 1 ATOM 1080 N NH2 . ARG A 1 156 ? 9.702 18.248 -7.149 1.00 50.69 ? 137 ARG A NH2 1 ATOM 1081 N N . ILE A 1 157 ? 3.654 21.779 -7.420 1.00 29.00 ? 138 ILE A N 1 ATOM 1082 C CA . ILE A 1 157 ? 3.724 22.858 -8.389 1.00 22.77 ? 138 ILE A CA 1 ATOM 1083 C C . ILE A 1 157 ? 4.680 23.939 -7.914 1.00 22.48 ? 138 ILE A C 1 ATOM 1084 O O . ILE A 1 157 ? 4.522 24.490 -6.819 1.00 25.13 ? 138 ILE A O 1 ATOM 1085 C CB . ILE A 1 157 ? 2.358 23.487 -8.588 1.00 25.18 ? 138 ILE A CB 1 ATOM 1086 C CG1 . ILE A 1 157 ? 1.381 22.435 -9.107 1.00 25.82 ? 138 ILE A CG1 1 ATOM 1087 C CG2 . ILE A 1 157 ? 2.452 24.679 -9.544 1.00 18.67 ? 138 ILE A CG2 1 ATOM 1088 C CD1 . ILE A 1 157 ? 0.098 23.018 -9.637 1.00 25.85 ? 138 ILE A CD1 1 ATOM 1089 N N . LYS A 1 158 ? 5.672 24.248 -8.736 1.00 22.85 ? 139 LYS A N 1 ATOM 1090 C CA . LYS A 1 158 ? 6.720 25.181 -8.339 1.00 23.46 ? 139 LYS A CA 1 ATOM 1091 C C . LYS A 1 158 ? 6.523 26.529 -9.050 1.00 26.41 ? 139 LYS A C 1 ATOM 1092 O O . LYS A 1 158 ? 6.575 26.615 -10.289 1.00 26.90 ? 139 LYS A O 1 ATOM 1093 C CB . LYS A 1 158 ? 8.096 24.565 -8.635 1.00 23.18 ? 139 LYS A CB 1 ATOM 1094 C CG . LYS A 1 158 ? 9.265 25.503 -8.417 1.00 42.03 ? 139 LYS A CG 1 ATOM 1095 C CD . LYS A 1 158 ? 10.537 24.984 -9.109 1.00 53.71 ? 139 LYS A CD 1 ATOM 1096 C CE . LYS A 1 158 ? 11.612 26.085 -9.293 1.00 43.11 ? 139 LYS A CE 1 ATOM 1097 N NZ . LYS A 1 158 ? 12.920 25.513 -9.766 1.00 52.78 ? 139 LYS A NZ 1 ATOM 1098 N N . ILE A 1 159 ? 6.288 27.581 -8.270 1.00 23.06 ? 140 ILE A N 1 ATOM 1099 C CA . ILE A 1 159 ? 6.035 28.905 -8.841 1.00 19.33 ? 140 ILE A CA 1 ATOM 1100 C C . ILE A 1 159 ? 6.997 29.963 -8.316 1.00 15.75 ? 140 ILE A C 1 ATOM 1101 O O . ILE A 1 159 ? 7.161 30.112 -7.113 1.00 18.74 ? 140 ILE A O 1 ATOM 1102 C CB . ILE A 1 159 ? 4.614 29.347 -8.525 1.00 22.88 ? 140 ILE A CB 1 ATOM 1103 C CG1 . ILE A 1 159 ? 3.611 28.368 -9.146 1.00 22.38 ? 140 ILE A CG1 1 ATOM 1104 C CG2 . ILE A 1 159 ? 4.373 30.773 -9.017 1.00 19.99 ? 140 ILE A CG2 1 ATOM 1105 C CD1 . ILE A 1 159 ? 2.139 28.762 -8.922 1.00 26.86 ? 140 ILE A CD1 1 ATOM 1106 N N . GLY A 1 160 ? 7.624 30.708 -9.213 1.00 18.54 ? 141 GLY A N 1 ATOM 1107 C CA . GLY A 1 160 ? 8.538 31.773 -8.811 1.00 19.70 ? 141 GLY A CA 1 ATOM 1108 C C . GLY A 1 160 ? 8.748 32.859 -9.866 1.00 20.76 ? 141 GLY A C 1 ATOM 1109 O O . GLY A 1 160 ? 8.250 32.766 -10.993 1.00 19.11 ? 141 GLY A O 1 ATOM 1110 N N . SER A 1 161 ? 9.484 33.905 -9.508 1.00 22.06 ? 142 SER A N 1 ATOM 1111 C CA . SER A 1 161 ? 9.864 34.915 -10.504 1.00 20.54 ? 142 SER A CA 1 ATOM 1112 C C . SER A 1 161 ? 10.815 34.365 -11.574 1.00 18.05 ? 142 SER A C 1 ATOM 1113 O O . SER A 1 161 ? 11.771 33.649 -11.271 1.00 24.20 ? 142 SER A O 1 ATOM 1114 C CB . SER A 1 161 ? 10.531 36.109 -9.841 1.00 23.82 ? 142 SER A CB 1 ATOM 1115 O OG . SER A 1 161 ? 10.957 37.019 -10.843 1.00 24.00 ? 142 SER A OG 1 ATOM 1116 N N . TRP A 1 162 ? 10.572 34.728 -12.824 1.00 16.98 ? 143 TRP A N 1 ATOM 1117 C CA . TRP A 1 162 ? 11.338 34.170 -13.927 1.00 16.69 ? 143 TRP A CA 1 ATOM 1118 C C . TRP A 1 162 ? 12.641 34.899 -14.173 1.00 19.37 ? 143 TRP A C 1 ATOM 1119 O O . TRP A 1 162 ? 13.624 34.278 -14.576 1.00 24.02 ? 143 TRP A O 1 ATOM 1120 C CB . TRP A 1 162 ? 10.506 34.152 -15.218 1.00 20.38 ? 143 TRP A CB 1 ATOM 1121 C CG . TRP A 1 162 ? 11.097 33.264 -16.286 1.00 19.45 ? 143 TRP A CG 1 ATOM 1122 C CD1 . TRP A 1 162 ? 11.717 33.659 -17.435 1.00 17.01 ? 143 TRP A CD1 1 ATOM 1123 C CD2 . TRP A 1 162 ? 11.127 31.829 -16.291 1.00 22.98 ? 143 TRP A CD2 1 ATOM 1124 N NE1 . TRP A 1 162 ? 12.128 32.563 -18.154 1.00 17.59 ? 143 TRP A NE1 1 ATOM 1125 C CE2 . TRP A 1 162 ? 11.772 31.421 -17.480 1.00 20.37 ? 143 TRP A CE2 1 ATOM 1126 C CE3 . TRP A 1 162 ? 10.674 30.841 -15.400 1.00 24.22 ? 143 TRP A CE3 1 ATOM 1127 C CZ2 . TRP A 1 162 ? 11.981 30.076 -17.808 1.00 20.37 ? 143 TRP A CZ2 1 ATOM 1128 C CZ3 . TRP A 1 162 ? 10.876 29.495 -15.723 1.00 19.55 ? 143 TRP A CZ3 1 ATOM 1129 C CH2 . TRP A 1 162 ? 11.528 29.128 -16.913 1.00 19.26 ? 143 TRP A CH2 1 ATOM 1130 N N . THR A 1 163 ? 12.651 36.215 -13.949 1.00 22.40 ? 144 THR A N 1 ATOM 1131 C CA . THR A 1 163 ? 13.838 37.042 -14.245 1.00 23.50 ? 144 THR A CA 1 ATOM 1132 C C . THR A 1 163 ? 14.405 37.839 -13.069 1.00 23.97 ? 144 THR A C 1 ATOM 1133 O O . THR A 1 163 ? 15.466 38.442 -13.195 1.00 34.72 ? 144 THR A O 1 ATOM 1134 C CB . THR A 1 163 ? 13.593 38.045 -15.401 1.00 21.06 ? 144 THR A CB 1 ATOM 1135 O OG1 . THR A 1 163 ? 12.634 39.028 -14.985 1.00 19.63 ? 144 THR A OG1 1 ATOM 1136 C CG2 . THR A 1 163 ? 13.098 37.336 -16.640 1.00 19.85 ? 144 THR A CG2 1 ATOM 1137 N N . HIS A 1 164 ? 13.697 37.883 -11.950 1.00 19.59 ? 145 HIS A N 1 ATOM 1138 C CA . HIS A 1 164 ? 14.169 38.666 -10.814 1.00 19.52 ? 145 HIS A CA 1 ATOM 1139 C C . HIS A 1 164 ? 14.696 37.788 -9.682 1.00 22.92 ? 145 HIS A C 1 ATOM 1140 O O . HIS A 1 164 ? 13.986 36.907 -9.194 1.00 24.38 ? 145 HIS A O 1 ATOM 1141 C CB . HIS A 1 164 ? 13.052 39.570 -10.294 1.00 24.77 ? 145 HIS A CB 1 ATOM 1142 C CG . HIS A 1 164 ? 12.658 40.659 -11.248 1.00 30.06 ? 145 HIS A CG 1 ATOM 1143 N ND1 . HIS A 1 164 ? 13.462 41.752 -11.498 1.00 29.09 ? 145 HIS A ND1 1 ATOM 1144 C CD2 . HIS A 1 164 ? 11.545 40.824 -12.001 1.00 27.93 ? 145 HIS A CD2 1 ATOM 1145 C CE1 . HIS A 1 164 ? 12.859 42.541 -12.372 1.00 28.53 ? 145 HIS A CE1 1 ATOM 1146 N NE2 . HIS A 1 164 ? 11.694 42.008 -12.690 1.00 25.74 ? 145 HIS A NE2 1 ATOM 1147 N N . HIS A 1 165 ? 15.934 38.029 -9.252 1.00 25.53 ? 146 HIS A N 1 ATOM 1148 C CA . HIS A 1 165 ? 16.523 37.252 -8.149 1.00 28.12 ? 146 HIS A CA 1 ATOM 1149 C C . HIS A 1 165 ? 16.011 37.669 -6.755 1.00 25.89 ? 146 HIS A C 1 ATOM 1150 O O . HIS A 1 165 ? 15.167 38.543 -6.634 1.00 24.54 ? 146 HIS A O 1 ATOM 1151 C CB . HIS A 1 165 ? 18.056 37.245 -8.222 1.00 30.25 ? 146 HIS A CB 1 ATOM 1152 C CG . HIS A 1 165 ? 18.671 38.597 -8.117 1.00 34.75 ? 146 HIS A CG 1 ATOM 1153 N ND1 . HIS A 1 165 ? 18.567 39.395 -6.997 1.00 34.48 ? 146 HIS A ND1 1 ATOM 1154 C CD2 . HIS A 1 165 ? 19.422 39.313 -9.006 1.00 37.60 ? 146 HIS A CD2 1 ATOM 1155 C CE1 . HIS A 1 165 ? 19.206 40.529 -7.191 1.00 31.59 ? 146 HIS A CE1 1 ATOM 1156 N NE2 . HIS A 1 165 ? 19.741 40.496 -8.405 1.00 34.56 ? 146 HIS A NE2 1 ATOM 1157 N N . SER A 1 166 ? 16.537 37.038 -5.711 1.00 31.39 ? 147 SER A N 1 ATOM 1158 C CA . SER A 1 166 ? 15.976 37.139 -4.356 1.00 28.44 ? 147 SER A CA 1 ATOM 1159 C C . SER A 1 166 ? 16.084 38.519 -3.700 1.00 29.04 ? 147 SER A C 1 ATOM 1160 O O . SER A 1 166 ? 15.404 38.780 -2.705 1.00 31.32 ? 147 SER A O 1 ATOM 1161 C CB . SER A 1 166 ? 16.657 36.121 -3.456 1.00 28.93 ? 147 SER A CB 1 ATOM 1162 O OG . SER A 1 166 ? 18.027 36.467 -3.334 1.00 41.37 ? 147 SER A OG 1 ATOM 1163 N N . ARG A 1 167 ? 16.938 39.391 -4.231 1.00 29.12 ? 148 ARG A N 1 ATOM 1164 C CA . ARG A 1 167 ? 17.079 40.734 -3.668 1.00 29.53 ? 148 ARG A CA 1 ATOM 1165 C C . ARG A 1 167 ? 16.159 41.721 -4.367 1.00 26.81 ? 148 ARG A C 1 ATOM 1166 O O . ARG A 1 167 ? 16.054 42.872 -3.962 1.00 36.04 ? 148 ARG A O 1 ATOM 1167 C CB . ARG A 1 167 ? 18.522 41.237 -3.756 1.00 39.31 ? 148 ARG A CB 1 ATOM 1168 C CG . ARG A 1 167 ? 19.524 40.514 -2.858 1.00 43.53 ? 148 ARG A CG 1 ATOM 1169 C CD . ARG A 1 167 ? 20.938 41.137 -2.979 1.00 71.81 ? 148 ARG A CD 1 ATOM 1170 N NE . ARG A 1 167 ? 21.094 42.044 -4.131 1.00 78.63 ? 148 ARG A NE 1 ATOM 1171 C CZ . ARG A 1 167 ? 22.147 42.063 -4.959 1.00 81.74 ? 148 ARG A CZ 1 ATOM 1172 N NH1 . ARG A 1 167 ? 23.165 41.219 -4.783 1.00 71.29 ? 148 ARG A NH1 1 ATOM 1173 N NH2 . ARG A 1 167 ? 22.179 42.925 -5.974 1.00 68.72 ? 148 ARG A NH2 1 ATOM 1174 N N . GLU A 1 168 ? 15.501 41.265 -5.425 1.00 30.76 ? 149 GLU A N 1 ATOM 1175 C CA . GLU A 1 168 ? 14.547 42.089 -6.171 1.00 29.25 ? 149 GLU A CA 1 ATOM 1176 C C . GLU A 1 168 ? 13.085 41.681 -5.907 1.00 23.83 ? 149 GLU A C 1 ATOM 1177 O O . GLU A 1 168 ? 12.222 42.529 -5.648 1.00 24.35 ? 149 GLU A O 1 ATOM 1178 C CB . GLU A 1 168 ? 14.885 42.063 -7.676 1.00 26.21 ? 149 GLU A CB 1 ATOM 1179 C CG . GLU A 1 168 ? 16.213 42.741 -8.024 1.00 32.54 ? 149 GLU A CG 1 ATOM 1180 C CD . GLU A 1 168 ? 16.604 42.598 -9.490 1.00 39.05 ? 149 GLU A CD 1 ATOM 1181 O OE1 . GLU A 1 168 ? 16.273 41.554 -10.088 1.00 41.74 ? 149 GLU A OE1 1 ATOM 1182 O OE2 . GLU A 1 168 ? 17.243 43.529 -10.042 1.00 46.76 ? 149 GLU A OE2 1 ATOM 1183 N N . ILE A 1 169 ? 12.817 40.381 -5.994 1.00 20.60 ? 150 ILE A N 1 ATOM 1184 C CA . ILE A 1 169 ? 11.519 39.820 -5.639 1.00 18.57 ? 150 ILE A CA 1 ATOM 1185 C C . ILE A 1 169 ? 11.691 38.648 -4.675 1.00 20.72 ? 150 ILE A C 1 ATOM 1186 O O . ILE A 1 169 ? 12.475 37.729 -4.930 1.00 26.54 ? 150 ILE A O 1 ATOM 1187 C CB . ILE A 1 169 ? 10.764 39.343 -6.886 1.00 21.17 ? 150 ILE A CB 1 ATOM 1188 C CG1 . ILE A 1 169 ? 10.313 40.554 -7.711 1.00 24.76 ? 150 ILE A CG1 1 ATOM 1189 C CG2 . ILE A 1 169 ? 9.572 38.466 -6.498 1.00 20.94 ? 150 ILE A CG2 1 ATOM 1190 C CD1 . ILE A 1 169 ? 9.481 40.226 -8.957 1.00 21.29 ? 150 ILE A CD1 1 ATOM 1191 N N . SER A 1 170 ? 10.982 38.688 -3.554 1.00 20.23 ? 151 SER A N 1 ATOM 1192 C CA . SER A 1 170 ? 10.873 37.511 -2.702 1.00 25.44 ? 151 SER A CA 1 ATOM 1193 C C . SER A 1 170 ? 9.434 36.975 -2.745 1.00 25.95 ? 151 SER A C 1 ATOM 1194 O O . SER A 1 170 ? 8.475 37.739 -2.629 1.00 30.67 ? 151 SER A O 1 ATOM 1195 C CB . SER A 1 170 ? 11.308 37.816 -1.273 1.00 23.70 ? 151 SER A CB 1 ATOM 1196 O OG . SER A 1 170 ? 10.408 38.726 -0.676 1.00 33.11 ? 151 SER A OG 1 ATOM 1197 N N . VAL A 1 171 ? 9.279 35.669 -2.931 1.00 25.72 ? 152 VAL A N 1 ATOM 1198 C CA . VAL A 1 171 ? 7.955 35.047 -2.874 1.00 33.11 ? 152 VAL A CA 1 ATOM 1199 C C . VAL A 1 171 ? 7.782 34.285 -1.573 1.00 29.16 ? 152 VAL A C 1 ATOM 1200 O O . VAL A 1 171 ? 8.702 33.620 -1.120 1.00 33.73 ? 152 VAL A O 1 ATOM 1201 C CB . VAL A 1 171 ? 7.717 34.072 -4.045 1.00 27.66 ? 152 VAL A CB 1 ATOM 1202 C CG1 . VAL A 1 171 ? 7.360 34.829 -5.297 1.00 20.10 ? 152 VAL A CG1 1 ATOM 1203 C CG2 . VAL A 1 171 ? 8.946 33.222 -4.271 1.00 26.17 ? 152 VAL A CG2 1 ATOM 1204 N N . ASP A 1 172 ? 6.599 34.381 -0.980 1.00 30.30 ? 153 ASP A N 1 ATOM 1205 C CA . ASP A 1 172 ? 6.317 33.736 0.296 1.00 36.70 ? 153 ASP A CA 1 ATOM 1206 C C . ASP A 1 172 ? 4.900 33.164 0.263 1.00 37.15 ? 153 ASP A C 1 ATOM 1207 O O . ASP A 1 172 ? 4.013 33.722 -0.374 1.00 33.27 ? 153 ASP A O 1 ATOM 1208 C CB . ASP A 1 172 ? 6.464 34.743 1.456 1.00 44.12 ? 153 ASP A CB 1 ATOM 1209 C CG . ASP A 1 172 ? 7.653 35.718 1.265 1.00 60.29 ? 153 ASP A CG 1 ATOM 1210 O OD1 . ASP A 1 172 ? 8.804 35.314 1.584 1.00 62.12 ? 153 ASP A OD1 1 ATOM 1211 O OD2 . ASP A 1 172 ? 7.431 36.881 0.802 1.00 44.17 ? 153 ASP A OD2 1 ATOM 1212 N N . PRO A 1 173 ? 4.684 32.025 0.929 1.00 43.72 ? 154 PRO A N 1 ATOM 1213 C CA . PRO A 1 173 ? 3.330 31.470 1.074 1.00 33.06 ? 154 PRO A CA 1 ATOM 1214 C C . PRO A 1 173 ? 2.523 32.325 2.028 1.00 38.16 ? 154 PRO A C 1 ATOM 1215 O O . PRO A 1 173 ? 3.119 33.035 2.849 1.00 42.97 ? 154 PRO A O 1 ATOM 1216 C CB . PRO A 1 173 ? 3.584 30.110 1.721 1.00 34.36 ? 154 PRO A CB 1 ATOM 1217 C CG . PRO A 1 173 ? 5.030 29.813 1.438 1.00 33.55 ? 154 PRO A CG 1 ATOM 1218 C CD . PRO A 1 173 ? 5.714 31.133 1.484 1.00 38.28 ? 154 PRO A CD 1 ATOM 1219 N N . THR A 1 174 ? 1.199 32.253 1.940 1.00 41.93 ? 155 THR A N 1 ATOM 1220 C CA . THR A 1 174 ? 0.317 33.079 2.777 1.00 48.78 ? 155 THR A CA 1 ATOM 1221 C C . THR A 1 174 ? 0.066 32.477 4.163 1.00 60.30 ? 155 THR A C 1 ATOM 1222 O O . THR A 1 174 ? -0.084 31.264 4.294 1.00 62.86 ? 155 THR A O 1 ATOM 1223 C CB . THR A 1 174 ? -1.039 33.304 2.082 1.00 50.90 ? 155 THR A CB 1 ATOM 1224 O OG1 . THR A 1 174 ? -0.847 34.139 0.930 1.00 48.93 ? 155 THR A OG1 1 ATOM 1225 C CG2 . THR A 1 174 ? -2.043 33.968 3.021 1.00 56.42 ? 155 THR A CG2 1 ATOM 1226 N N . THR A 1 175 ? -0.005 33.317 5.194 1.00 60.85 ? 156 THR A N 1 ATOM 1227 C CA . THR A 1 175 ? -0.352 32.835 6.535 1.00 70.87 ? 156 THR A CA 1 ATOM 1228 C C . THR A 1 175 ? -1.767 32.217 6.607 1.00 74.15 ? 156 THR A C 1 ATOM 1229 O O . THR A 1 175 ? -2.777 32.911 6.772 1.00 67.36 ? 156 THR A O 1 ATOM 1230 C CB . THR A 1 175 ? -0.196 33.949 7.588 1.00 68.22 ? 156 THR A CB 1 ATOM 1231 O OG1 . THR A 1 175 ? 1.022 34.670 7.354 1.00 65.98 ? 156 THR A OG1 1 ATOM 1232 C CG2 . THR A 1 175 ? -0.179 33.358 8.992 1.00 61.76 ? 156 THR A CG2 1 ATOM 1233 N N . ASP A 1 180 ? -9.192 24.220 2.213 1.00 49.18 ? 161 ASP A N 1 ATOM 1234 C CA . ASP A 1 180 ? -8.423 23.596 1.142 1.00 63.40 ? 161 ASP A CA 1 ATOM 1235 C C . ASP A 1 180 ? -9.280 23.338 -0.054 1.00 50.36 ? 161 ASP A C 1 ATOM 1236 O O . ASP A 1 180 ? -8.985 23.718 -1.153 1.00 45.94 ? 161 ASP A O 1 ATOM 1237 C CB . ASP A 1 180 ? -7.815 22.286 1.608 1.00 57.32 ? 161 ASP A CB 1 ATOM 1238 C CG . ASP A 1 180 ? -6.741 22.480 2.634 1.00 67.11 ? 161 ASP A CG 1 ATOM 1239 O OD1 . ASP A 1 180 ? -6.338 23.622 2.858 1.00 63.50 ? 161 ASP A OD1 1 ATOM 1240 O OD2 . ASP A 1 180 ? -6.304 21.486 3.227 1.00 61.93 ? 161 ASP A OD2 1 ATOM 1241 N N . SER A 1 181 ? -10.369 22.679 0.203 1.00 55.99 ? 162 SER A N 1 ATOM 1242 C CA . SER A 1 181 ? -11.355 22.355 -0.792 1.00 56.46 ? 162 SER A CA 1 ATOM 1243 C C . SER A 1 181 ? -12.529 23.298 -0.597 1.00 50.05 ? 162 SER A C 1 ATOM 1244 O O . SER A 1 181 ? -13.647 22.970 -0.907 1.00 47.23 ? 162 SER A O 1 ATOM 1245 C CB . SER A 1 181 ? -11.727 20.869 -0.690 1.00 60.64 ? 162 SER A CB 1 ATOM 1246 O OG . SER A 1 181 ? -13.119 20.675 -0.686 1.00 50.79 ? 162 SER A OG 1 ATOM 1247 N N . GLU A 1 182 ? -12.234 24.457 -0.036 1.00 44.90 ? 163 GLU A N 1 ATOM 1248 C CA . GLU A 1 182 ? -13.202 25.447 0.327 1.00 45.88 ? 163 GLU A CA 1 ATOM 1249 C C . GLU A 1 182 ? -13.919 25.851 -0.915 1.00 47.50 ? 163 GLU A C 1 ATOM 1250 O O . GLU A 1 182 ? -15.092 26.102 -0.876 1.00 47.31 ? 163 GLU A O 1 ATOM 1251 C CB . GLU A 1 182 ? -12.470 26.638 0.899 1.00 52.03 ? 163 GLU A CB 1 ATOM 1252 C CG . GLU A 1 182 ? -13.286 27.606 1.723 1.00 65.85 ? 163 GLU A CG 1 ATOM 1253 C CD . GLU A 1 182 ? -12.575 28.942 1.956 1.00 82.02 ? 163 GLU A CD 1 ATOM 1254 O OE1 . GLU A 1 182 ? -11.458 28.972 2.490 1.00 77.95 ? 163 GLU A OE1 1 ATOM 1255 O OE2 . GLU A 1 182 ? -13.138 29.994 1.631 1.00 83.13 ? 163 GLU A OE2 1 ATOM 1256 N N . TYR A 1 183 ? -13.207 25.959 -2.021 1.00 44.13 ? 164 TYR A N 1 ATOM 1257 C CA . TYR A 1 183 ? -13.851 26.201 -3.271 1.00 38.97 ? 164 TYR A CA 1 ATOM 1258 C C . TYR A 1 183 ? -13.725 25.095 -4.267 1.00 32.42 ? 164 TYR A C 1 ATOM 1259 O O . TYR A 1 183 ? -13.989 25.295 -5.408 1.00 24.64 ? 164 TYR A O 1 ATOM 1260 C CB . TYR A 1 183 ? -13.312 27.447 -3.906 1.00 48.59 ? 164 TYR A CB 1 ATOM 1261 C CG . TYR A 1 183 ? -12.999 28.590 -3.014 1.00 44.83 ? 164 TYR A CG 1 ATOM 1262 C CD1 . TYR A 1 183 ? -13.965 29.234 -2.301 1.00 49.35 ? 164 TYR A CD1 1 ATOM 1263 C CD2 . TYR A 1 183 ? -11.746 29.058 -2.960 1.00 48.29 ? 164 TYR A CD2 1 ATOM 1264 C CE1 . TYR A 1 183 ? -13.652 30.296 -1.506 1.00 59.59 ? 164 TYR A CE1 1 ATOM 1265 C CE2 . TYR A 1 183 ? -11.420 30.120 -2.188 1.00 54.28 ? 164 TYR A CE2 1 ATOM 1266 C CZ . TYR A 1 183 ? -12.367 30.734 -1.470 1.00 69.47 ? 164 TYR A CZ 1 ATOM 1267 O OH . TYR A 1 183 ? -11.969 31.788 -0.716 1.00 77.87 ? 164 TYR A OH 1 ATOM 1268 N N . PHE A 1 184 ? -13.271 23.941 -3.843 1.00 33.68 ? 165 PHE A N 1 ATOM 1269 C CA . PHE A 1 184 ? -13.107 22.835 -4.748 1.00 35.47 ? 165 PHE A CA 1 ATOM 1270 C C . PHE A 1 184 ? -14.469 22.353 -5.162 1.00 35.58 ? 165 PHE A C 1 ATOM 1271 O O . PHE A 1 184 ? -15.386 22.388 -4.397 1.00 37.06 ? 165 PHE A O 1 ATOM 1272 C CB . PHE A 1 184 ? -12.270 21.747 -4.120 1.00 34.42 ? 165 PHE A CB 1 ATOM 1273 C CG . PHE A 1 184 ? -11.824 20.707 -5.060 1.00 30.51 ? 165 PHE A CG 1 ATOM 1274 C CD1 . PHE A 1 184 ? -10.833 20.950 -5.943 1.00 30.27 ? 165 PHE A CD1 1 ATOM 1275 C CD2 . PHE A 1 184 ? -12.358 19.477 -5.017 1.00 29.17 ? 165 PHE A CD2 1 ATOM 1276 C CE1 . PHE A 1 184 ? -10.412 19.990 -6.801 1.00 30.04 ? 165 PHE A CE1 1 ATOM 1277 C CE2 . PHE A 1 184 ? -11.951 18.514 -5.876 1.00 28.06 ? 165 PHE A CE2 1 ATOM 1278 C CZ . PHE A 1 184 ? -10.978 18.766 -6.771 1.00 26.61 ? 165 PHE A CZ 1 ATOM 1279 N N . SER A 1 185 ? -14.581 21.935 -6.403 1.00 31.75 ? 166 SER A N 1 ATOM 1280 C CA . SER A 1 185 ? -15.833 21.489 -6.989 1.00 31.00 ? 166 SER A CA 1 ATOM 1281 C C . SER A 1 185 ? -16.260 20.133 -6.432 1.00 33.79 ? 166 SER A C 1 ATOM 1282 O O . SER A 1 185 ? -15.486 19.166 -6.447 1.00 37.46 ? 166 SER A O 1 ATOM 1283 C CB . SER A 1 185 ? -15.692 21.406 -8.510 1.00 29.60 ? 166 SER A CB 1 ATOM 1284 O OG . SER A 1 185 ? -16.932 21.106 -9.120 1.00 31.93 ? 166 SER A OG 1 ATOM 1285 N N . GLN A 1 186 ? -17.498 20.064 -5.950 1.00 35.23 ? 167 GLN A N 1 ATOM 1286 C CA . GLN A 1 186 ? -18.083 18.796 -5.523 1.00 36.85 ? 167 GLN A CA 1 ATOM 1287 C C . GLN A 1 186 ? -18.331 17.857 -6.703 1.00 35.45 ? 167 GLN A C 1 ATOM 1288 O O . GLN A 1 186 ? -18.492 16.661 -6.500 1.00 42.89 ? 167 GLN A O 1 ATOM 1289 C CB . GLN A 1 186 ? -19.397 19.044 -4.786 1.00 32.86 ? 167 GLN A CB 1 ATOM 1290 C CG . GLN A 1 186 ? -20.204 20.176 -5.406 1.00 44.27 ? 167 GLN A CG 1 ATOM 1291 C CD . GLN A 1 186 ? -21.614 20.316 -4.840 1.00 64.01 ? 167 GLN A CD 1 ATOM 1292 O OE1 . GLN A 1 186 ? -22.229 19.336 -4.379 1.00 75.84 ? 167 GLN A OE1 1 ATOM 1293 N NE2 . GLN A 1 186 ? -22.141 21.547 -4.878 1.00 53.59 ? 167 GLN A NE2 1 ATOM 1294 N N . TYR A 1 187 ? -18.361 18.390 -7.925 1.00 25.14 ? 168 TYR A N 1 ATOM 1295 C CA . TYR A 1 187 ? -18.631 17.562 -9.097 1.00 27.45 ? 168 TYR A CA 1 ATOM 1296 C C . TYR A 1 187 ? -17.386 16.997 -9.795 1.00 24.55 ? 168 TYR A C 1 ATOM 1297 O O . TYR A 1 187 ? -17.505 16.225 -10.738 1.00 31.82 ? 168 TYR A O 1 ATOM 1298 C CB . TYR A 1 187 ? -19.542 18.306 -10.078 1.00 33.99 ? 168 TYR A CB 1 ATOM 1299 C CG . TYR A 1 187 ? -20.791 18.816 -9.406 1.00 36.80 ? 168 TYR A CG 1 ATOM 1300 C CD1 . TYR A 1 187 ? -21.723 17.929 -8.897 1.00 36.19 ? 168 TYR A CD1 1 ATOM 1301 C CD2 . TYR A 1 187 ? -21.039 20.181 -9.268 1.00 39.07 ? 168 TYR A CD2 1 ATOM 1302 C CE1 . TYR A 1 187 ? -22.869 18.371 -8.260 1.00 37.93 ? 168 TYR A CE1 1 ATOM 1303 C CE2 . TYR A 1 187 ? -22.195 20.642 -8.631 1.00 42.44 ? 168 TYR A CE2 1 ATOM 1304 C CZ . TYR A 1 187 ? -23.106 19.723 -8.133 1.00 44.95 ? 168 TYR A CZ 1 ATOM 1305 O OH . TYR A 1 187 ? -24.258 20.143 -7.504 1.00 47.57 ? 168 TYR A OH 1 ATOM 1306 N N . SER A 1 188 ? -16.197 17.367 -9.334 1.00 22.14 ? 169 SER A N 1 ATOM 1307 C CA . SER A 1 188 ? -14.971 16.745 -9.836 1.00 24.71 ? 169 SER A CA 1 ATOM 1308 C C . SER A 1 188 ? -14.968 15.224 -9.617 1.00 25.68 ? 169 SER A C 1 ATOM 1309 O O . SER A 1 188 ? -15.616 14.719 -8.693 1.00 27.66 ? 169 SER A O 1 ATOM 1310 C CB . SER A 1 188 ? -13.752 17.358 -9.142 1.00 28.82 ? 169 SER A CB 1 ATOM 1311 O OG . SER A 1 188 ? -12.543 16.859 -9.695 1.00 29.93 ? 169 SER A OG 1 ATOM 1312 N N . ARG A 1 189 ? -14.234 14.491 -10.451 1.00 25.73 ? 170 ARG A N 1 ATOM 1313 C CA . ARG A 1 189 ? -14.050 13.050 -10.216 1.00 24.16 ? 170 ARG A CA 1 ATOM 1314 C C . ARG A 1 189 ? -13.047 12.801 -9.105 1.00 28.43 ? 170 ARG A C 1 ATOM 1315 O O . ARG A 1 189 ? -12.769 11.652 -8.757 1.00 31.86 ? 170 ARG A O 1 ATOM 1316 C CB . ARG A 1 189 ? -13.586 12.306 -11.481 1.00 22.07 ? 170 ARG A CB 1 ATOM 1317 C CG . ARG A 1 189 ? -14.591 12.332 -12.623 1.00 37.30 ? 170 ARG A CG 1 ATOM 1318 C CD . ARG A 1 189 ? -14.658 11.011 -13.358 1.00 36.48 ? 170 ARG A CD 1 ATOM 1319 N NE . ARG A 1 189 ? -13.381 10.669 -13.978 1.00 45.43 ? 170 ARG A NE 1 ATOM 1320 C CZ . ARG A 1 189 ? -13.008 9.428 -14.271 1.00 52.32 ? 170 ARG A CZ 1 ATOM 1321 N NH1 . ARG A 1 189 ? -13.811 8.408 -13.991 1.00 52.80 ? 170 ARG A NH1 1 ATOM 1322 N NH2 . ARG A 1 189 ? -11.826 9.208 -14.833 1.00 56.70 ? 170 ARG A NH2 1 ATOM 1323 N N . PHE A 1 190 ? -12.477 13.874 -8.565 1.00 32.43 ? 171 PHE A N 1 ATOM 1324 C CA . PHE A 1 190 ? -11.396 13.729 -7.599 1.00 26.92 ? 171 PHE A CA 1 ATOM 1325 C C . PHE A 1 190 ? -11.705 14.517 -6.355 1.00 24.53 ? 171 PHE A C 1 ATOM 1326 O O . PHE A 1 190 ? -12.605 15.347 -6.356 1.00 30.17 ? 171 PHE A O 1 ATOM 1327 C CB . PHE A 1 190 ? -10.063 14.195 -8.186 1.00 27.45 ? 171 PHE A CB 1 ATOM 1328 C CG . PHE A 1 190 ? -9.702 13.530 -9.481 1.00 22.80 ? 171 PHE A CG 1 ATOM 1329 C CD1 . PHE A 1 190 ? -10.218 13.996 -10.680 1.00 24.93 ? 171 PHE A CD1 1 ATOM 1330 C CD2 . PHE A 1 190 ? -8.846 12.447 -9.501 1.00 26.05 ? 171 PHE A CD2 1 ATOM 1331 C CE1 . PHE A 1 190 ? -9.891 13.388 -11.892 1.00 26.68 ? 171 PHE A CE1 1 ATOM 1332 C CE2 . PHE A 1 190 ? -8.517 11.830 -10.701 1.00 26.61 ? 171 PHE A CE2 1 ATOM 1333 C CZ . PHE A 1 190 ? -9.040 12.311 -11.900 1.00 27.40 ? 171 PHE A CZ 1 ATOM 1334 N N . GLU A 1 191 ? -10.958 14.235 -5.291 1.00 35.69 ? 172 GLU A N 1 ATOM 1335 C CA . GLU A 1 191 ? -11.095 14.960 -4.029 1.00 38.57 ? 172 GLU A CA 1 ATOM 1336 C C . GLU A 1 191 ? -9.730 15.307 -3.421 1.00 35.30 ? 172 GLU A C 1 ATOM 1337 O O . GLU A 1 191 ? -8.734 14.589 -3.629 1.00 34.16 ? 172 GLU A O 1 ATOM 1338 C CB . GLU A 1 191 ? -11.961 14.171 -3.044 1.00 35.19 ? 172 GLU A CB 1 ATOM 1339 C CG . GLU A 1 191 ? -11.428 12.801 -2.672 1.00 35.13 ? 172 GLU A CG 1 ATOM 1340 C CD . GLU A 1 191 ? -12.422 12.036 -1.804 1.00 54.71 ? 172 GLU A CD 1 ATOM 1341 O OE1 . GLU A 1 191 ? -13.406 12.677 -1.354 1.00 61.40 ? 172 GLU A OE1 1 ATOM 1342 O OE2 . GLU A 1 191 ? -12.236 10.806 -1.583 1.00 57.22 ? 172 GLU A OE2 1 ATOM 1343 N N . ILE A 1 192 ? -9.681 16.415 -2.686 1.00 30.86 ? 173 ILE A N 1 ATOM 1344 C CA . ILE A 1 192 ? -8.417 16.866 -2.113 1.00 34.49 ? 173 ILE A CA 1 ATOM 1345 C C . ILE A 1 192 ? -8.280 16.312 -0.697 1.00 32.96 ? 173 ILE A C 1 ATOM 1346 O O . ILE A 1 192 ? -9.204 16.413 0.099 1.00 33.93 ? 173 ILE A O 1 ATOM 1347 C CB . ILE A 1 192 ? -8.282 18.414 -2.149 1.00 31.37 ? 173 ILE A CB 1 ATOM 1348 C CG1 . ILE A 1 192 ? -8.327 18.915 -3.591 1.00 30.44 ? 173 ILE A CG1 1 ATOM 1349 C CG2 . ILE A 1 192 ? -6.995 18.874 -1.487 1.00 32.10 ? 173 ILE A CG2 1 ATOM 1350 C CD1 . ILE A 1 192 ? -8.306 20.424 -3.714 1.00 30.77 ? 173 ILE A CD1 1 ATOM 1351 N N . LEU A 1 193 ? -7.126 15.715 -0.408 1.00 37.21 ? 174 LEU A N 1 ATOM 1352 C CA . LEU A 1 193 ? -6.823 15.163 0.913 1.00 34.96 ? 174 LEU A CA 1 ATOM 1353 C C . LEU A 1 193 ? -6.060 16.168 1.750 1.00 35.69 ? 174 LEU A C 1 ATOM 1354 O O . LEU A 1 193 ? -6.331 16.308 2.945 1.00 44.29 ? 174 LEU A O 1 ATOM 1355 C CB . LEU A 1 193 ? -6.016 13.869 0.789 1.00 33.81 ? 174 LEU A CB 1 ATOM 1356 C CG . LEU A 1 193 ? -6.701 12.845 -0.119 1.00 31.97 ? 174 LEU A CG 1 ATOM 1357 C CD1 . LEU A 1 193 ? -5.882 11.574 -0.280 1.00 30.83 ? 174 LEU A CD1 1 ATOM 1358 C CD2 . LEU A 1 193 ? -8.112 12.537 0.388 1.00 35.00 ? 174 LEU A CD2 1 ATOM 1359 N N . ASP A 1 194 ? -5.114 16.867 1.120 1.00 34.15 ? 175 ASP A N 1 ATOM 1360 C CA . ASP A 1 194 ? -4.339 17.909 1.803 1.00 37.94 ? 175 ASP A CA 1 ATOM 1361 C C . ASP A 1 194 ? -3.563 18.848 0.861 1.00 32.72 ? 175 ASP A C 1 ATOM 1362 O O . ASP A 1 194 ? -3.160 18.458 -0.241 1.00 34.00 ? 175 ASP A O 1 ATOM 1363 C CB . ASP A 1 194 ? -3.368 17.263 2.796 1.00 41.92 ? 175 ASP A CB 1 ATOM 1364 C CG . ASP A 1 194 ? -2.912 18.225 3.870 1.00 57.24 ? 175 ASP A CG 1 ATOM 1365 O OD1 . ASP A 1 194 ? -3.749 19.060 4.297 1.00 64.69 ? 175 ASP A OD1 1 ATOM 1366 O OD2 . ASP A 1 194 ? -1.725 18.150 4.276 1.00 53.10 ? 175 ASP A OD2 1 ATOM 1367 N N . VAL A 1 195 ? -3.346 20.080 1.309 1.00 28.35 ? 176 VAL A N 1 ATOM 1368 C CA . VAL A 1 195 ? -2.514 21.021 0.571 1.00 30.62 ? 176 VAL A CA 1 ATOM 1369 C C . VAL A 1 195 ? -1.458 21.644 1.476 1.00 30.65 ? 176 VAL A C 1 ATOM 1370 O O . VAL A 1 195 ? -1.801 22.293 2.450 1.00 35.65 ? 176 VAL A O 1 ATOM 1371 C CB . VAL A 1 195 ? -3.340 22.163 -0.039 1.00 23.65 ? 176 VAL A CB 1 ATOM 1372 C CG1 . VAL A 1 195 ? -2.415 23.147 -0.719 1.00 21.49 ? 176 VAL A CG1 1 ATOM 1373 C CG2 . VAL A 1 195 ? -4.369 21.624 -1.020 1.00 29.52 ? 176 VAL A CG2 1 ATOM 1374 N N . THR A 1 196 ? -0.182 21.457 1.144 1.00 26.39 ? 177 THR A N 1 ATOM 1375 C CA . THR A 1 196 ? 0.914 22.074 1.896 1.00 26.35 ? 177 THR A CA 1 ATOM 1376 C C . THR A 1 196 ? 1.757 23.012 1.035 1.00 26.17 ? 177 THR A C 1 ATOM 1377 O O . THR A 1 196 ? 1.853 22.832 -0.175 1.00 28.89 ? 177 THR A O 1 ATOM 1378 C CB . THR A 1 196 ? 1.842 21.014 2.562 1.00 44.20 ? 177 THR A CB 1 ATOM 1379 O OG1 . THR A 1 196 ? 2.449 20.173 1.563 1.00 34.37 ? 177 THR A OG1 1 ATOM 1380 C CG2 . THR A 1 196 ? 1.065 20.151 3.555 1.00 44.91 ? 177 THR A CG2 1 ATOM 1381 N N . GLN A 1 197 ? 2.387 23.992 1.675 1.00 27.35 ? 178 GLN A N 1 ATOM 1382 C CA . GLN A 1 197 ? 3.170 25.008 0.978 1.00 25.12 ? 178 GLN A CA 1 ATOM 1383 C C . GLN A 1 197 ? 4.562 25.066 1.599 1.00 24.79 ? 178 GLN A C 1 ATOM 1384 O O . GLN A 1 197 ? 4.693 24.995 2.806 1.00 29.63 ? 178 GLN A O 1 ATOM 1385 C CB . GLN A 1 197 ? 2.479 26.391 1.092 1.00 23.69 ? 178 GLN A CB 1 ATOM 1386 C CG . GLN A 1 197 ? 1.017 26.416 0.596 1.00 38.97 ? 178 GLN A CG 1 ATOM 1387 C CD . GLN A 1 197 ? 0.544 27.799 0.105 1.00 56.60 ? 178 GLN A CD 1 ATOM 1388 O OE1 . GLN A 1 197 ? 0.986 28.822 0.625 1.00 56.69 ? 178 GLN A OE1 1 ATOM 1389 N NE2 . GLN A 1 197 ? -0.361 27.825 -0.910 1.00 52.82 ? 178 GLN A NE2 1 ATOM 1390 N N . LYS A 1 198 ? 5.613 25.187 0.799 1.00 25.06 ? 179 LYS A N 1 ATOM 1391 C CA . LYS A 1 198 ? 6.903 25.544 1.380 1.00 21.39 ? 179 LYS A CA 1 ATOM 1392 C C . LYS A 1 198 ? 7.705 26.429 0.435 1.00 24.85 ? 179 LYS A C 1 ATOM 1393 O O . LYS A 1 198 ? 7.480 26.412 -0.775 1.00 25.08 ? 179 LYS A O 1 ATOM 1394 C CB . LYS A 1 198 ? 7.697 24.306 1.773 1.00 23.43 ? 179 LYS A CB 1 ATOM 1395 C CG . LYS A 1 198 ? 8.594 23.781 0.675 1.00 31.57 ? 179 LYS A CG 1 ATOM 1396 C CD . LYS A 1 198 ? 9.448 22.618 1.164 1.00 35.21 ? 179 LYS A CD 1 ATOM 1397 C CE . LYS A 1 198 ? 10.175 21.929 0.002 1.00 40.58 ? 179 LYS A CE 1 ATOM 1398 N NZ . LYS A 1 198 ? 11.085 20.822 0.465 1.00 51.26 ? 179 LYS A NZ 1 ATOM 1399 N N . LYS A 1 199 ? 8.635 27.205 0.991 1.00 24.33 ? 180 LYS A N 1 ATOM 1400 C CA . LYS A 1 199 ? 9.436 28.131 0.194 1.00 23.20 ? 180 LYS A CA 1 ATOM 1401 C C . LYS A 1 199 ? 10.847 27.612 -0.130 1.00 27.25 ? 180 LYS A C 1 ATOM 1402 O O . LYS A 1 199 ? 11.530 27.108 0.744 1.00 29.54 ? 180 LYS A O 1 ATOM 1403 C CB . LYS A 1 199 ? 9.526 29.461 0.911 1.00 24.35 ? 180 LYS A CB 1 ATOM 1404 C CG . LYS A 1 199 ? 10.594 30.373 0.367 1.00 28.56 ? 180 LYS A CG 1 ATOM 1405 C CD . LYS A 1 199 ? 10.620 31.665 1.143 1.00 29.80 ? 180 LYS A CD 1 ATOM 1406 C CE . LYS A 1 199 ? 11.801 32.498 0.719 1.00 38.28 ? 180 LYS A CE 1 ATOM 1407 N NZ . LYS A 1 199 ? 11.755 33.864 1.327 1.00 56.74 ? 180 LYS A NZ 1 ATOM 1408 N N . ASN A 1 200 ? 11.272 27.729 -1.390 1.00 28.61 ? 181 ASN A N 1 ATOM 1409 C CA . ASN A 1 200 ? 12.632 27.350 -1.780 1.00 30.29 ? 181 ASN A CA 1 ATOM 1410 C C . ASN A 1 200 ? 13.488 28.508 -2.262 1.00 31.12 ? 181 ASN A C 1 ATOM 1411 O O . ASN A 1 200 ? 12.973 29.494 -2.777 1.00 31.21 ? 181 ASN A O 1 ATOM 1412 C CB . ASN A 1 200 ? 12.634 26.266 -2.854 1.00 32.34 ? 181 ASN A CB 1 ATOM 1413 C CG . ASN A 1 200 ? 11.766 25.091 -2.495 1.00 40.61 ? 181 ASN A CG 1 ATOM 1414 O OD1 . ASN A 1 200 ? 12.123 24.269 -1.645 1.00 41.80 ? 181 ASN A OD1 1 ATOM 1415 N ND2 . ASN A 1 200 ? 10.612 24.991 -3.161 1.00 42.79 ? 181 ASN A ND2 1 ATOM 1416 N N . SER A 1 201 ? 14.800 28.380 -2.080 1.00 35.05 ? 182 SER A N 1 ATOM 1417 C CA . SER A 1 201 ? 15.751 29.362 -2.583 1.00 35.34 ? 182 SER A CA 1 ATOM 1418 C C . SER A 1 201 ? 16.820 28.601 -3.353 1.00 33.02 ? 182 SER A C 1 ATOM 1419 O O . SER A 1 201 ? 17.582 27.844 -2.767 1.00 33.13 ? 182 SER A O 1 ATOM 1420 C CB . SER A 1 201 ? 16.369 30.143 -1.426 1.00 31.01 ? 182 SER A CB 1 ATOM 1421 O OG . SER A 1 201 ? 17.008 31.308 -1.901 1.00 35.49 ? 182 SER A OG 1 ATOM 1422 N N . VAL A 1 202 ? 16.847 28.788 -4.668 1.00 35.80 ? 183 VAL A N 1 ATOM 1423 C CA . VAL A 1 202 ? 17.633 27.960 -5.580 1.00 30.53 ? 183 VAL A CA 1 ATOM 1424 C C . VAL A 1 202 ? 18.672 28.804 -6.312 1.00 37.97 ? 183 VAL A C 1 ATOM 1425 O O . VAL A 1 202 ? 18.392 29.941 -6.736 1.00 38.99 ? 183 VAL A O 1 ATOM 1426 C CB . VAL A 1 202 ? 16.700 27.301 -6.628 1.00 34.61 ? 183 VAL A CB 1 ATOM 1427 C CG1 . VAL A 1 202 ? 17.486 26.479 -7.633 1.00 38.87 ? 183 VAL A CG1 1 ATOM 1428 C CG2 . VAL A 1 202 ? 15.653 26.461 -5.943 1.00 36.26 ? 183 VAL A CG2 1 ATOM 1429 N N . THR A 1 203 ? 19.876 28.254 -6.460 1.00 45.75 ? 184 THR A N 1 ATOM 1430 C CA . THR A 1 203 ? 20.881 28.865 -7.338 1.00 52.36 ? 184 THR A CA 1 ATOM 1431 C C . THR A 1 203 ? 21.035 28.096 -8.665 1.00 54.09 ? 184 THR A C 1 ATOM 1432 O O . THR A 1 203 ? 21.369 26.912 -8.668 1.00 60.39 ? 184 THR A O 1 ATOM 1433 C CB . THR A 1 203 ? 22.246 29.010 -6.637 1.00 44.54 ? 184 THR A CB 1 ATOM 1434 O OG1 . THR A 1 203 ? 22.141 29.962 -5.559 1.00 39.82 ? 184 THR A OG1 1 ATOM 1435 C CG2 . THR A 1 203 ? 23.297 29.470 -7.635 1.00 45.84 ? 184 THR A CG2 1 ATOM 1436 N N . TYR A 1 204 ? 20.780 28.768 -9.785 1.00 53.77 ? 185 TYR A N 1 ATOM 1437 C CA . TYR A 1 204 ? 20.905 28.130 -11.093 1.00 67.26 ? 185 TYR A CA 1 ATOM 1438 C C . TYR A 1 204 ? 22.316 28.277 -11.685 1.00 80.70 ? 185 TYR A C 1 ATOM 1439 O O . TYR A 1 204 ? 23.101 29.135 -11.259 1.00 74.04 ? 185 TYR A O 1 ATOM 1440 C CB . TYR A 1 204 ? 19.843 28.660 -12.063 1.00 64.43 ? 185 TYR A CB 1 ATOM 1441 C CG . TYR A 1 204 ? 18.436 28.358 -11.618 1.00 54.89 ? 185 TYR A CG 1 ATOM 1442 C CD1 . TYR A 1 204 ? 17.761 29.218 -10.761 1.00 48.53 ? 185 TYR A CD1 1 ATOM 1443 C CD2 . TYR A 1 204 ? 17.780 27.213 -12.050 1.00 53.67 ? 185 TYR A CD2 1 ATOM 1444 C CE1 . TYR A 1 204 ? 16.470 28.950 -10.341 1.00 45.80 ? 185 TYR A CE1 1 ATOM 1445 C CE2 . TYR A 1 204 ? 16.477 26.932 -11.640 1.00 53.78 ? 185 TYR A CE2 1 ATOM 1446 C CZ . TYR A 1 204 ? 15.824 27.805 -10.785 1.00 52.82 ? 185 TYR A CZ 1 ATOM 1447 O OH . TYR A 1 204 ? 14.531 27.533 -10.362 1.00 45.69 ? 185 TYR A OH 1 ATOM 1448 N N . SER A 1 205 ? 22.619 27.429 -12.670 1.00 89.27 ? 186 SER A N 1 ATOM 1449 C CA . SER A 1 205 ? 23.941 27.367 -13.295 1.00 88.05 ? 186 SER A CA 1 ATOM 1450 C C . SER A 1 205 ? 24.328 28.651 -14.039 1.00 79.71 ? 186 SER A C 1 ATOM 1451 O O . SER A 1 205 ? 25.500 28.890 -14.310 1.00 84.18 ? 186 SER A O 1 ATOM 1452 C CB . SER A 1 205 ? 24.015 26.160 -14.239 1.00 78.73 ? 186 SER A CB 1 ATOM 1453 O OG . SER A 1 205 ? 23.842 24.957 -13.517 1.00 72.09 ? 186 SER A OG 1 ATOM 1454 N N . CYS A 1 206 ? 23.342 29.478 -14.354 1.00 74.73 ? 187 CYS A N 1 ATOM 1455 C CA . CYS A 1 206 ? 23.588 30.674 -15.141 1.00 80.68 ? 187 CYS A CA 1 ATOM 1456 C C . CYS A 1 206 ? 24.182 31.826 -14.311 1.00 85.64 ? 187 CYS A C 1 ATOM 1457 O O . CYS A 1 206 ? 25.112 32.492 -14.764 1.00 79.28 ? 187 CYS A O 1 ATOM 1458 C CB . CYS A 1 206 ? 22.298 31.121 -15.852 1.00 88.00 ? 187 CYS A CB 1 ATOM 1459 S SG . CYS A 1 206 ? 21.117 32.081 -14.805 1.00 107.43 ? 187 CYS A SG 1 ATOM 1460 N N . CYS A 1 207 ? 23.657 32.045 -13.102 1.00 88.94 ? 188 CYS A N 1 ATOM 1461 C CA . CYS A 1 207 ? 23.939 33.261 -12.314 1.00 82.41 ? 188 CYS A CA 1 ATOM 1462 C C . CYS A 1 207 ? 24.322 32.941 -10.852 1.00 78.57 ? 188 CYS A C 1 ATOM 1463 O O . CYS A 1 207 ? 23.925 31.902 -10.316 1.00 80.82 ? 188 CYS A O 1 ATOM 1464 C CB . CYS A 1 207 ? 22.718 34.206 -12.361 1.00 68.89 ? 188 CYS A CB 1 ATOM 1465 S SG . CYS A 1 207 ? 21.439 33.703 -13.587 1.00 95.82 ? 188 CYS A SG 1 ATOM 1466 N N . PRO A 1 208 ? 25.093 33.835 -10.201 1.00 73.19 ? 189 PRO A N 1 ATOM 1467 C CA . PRO A 1 208 ? 25.514 33.660 -8.799 1.00 60.15 ? 189 PRO A CA 1 ATOM 1468 C C . PRO A 1 208 ? 24.443 34.079 -7.776 1.00 60.90 ? 189 PRO A C 1 ATOM 1469 O O . PRO A 1 208 ? 24.650 33.936 -6.578 1.00 66.31 ? 189 PRO A O 1 ATOM 1470 C CB . PRO A 1 208 ? 26.703 34.614 -8.685 1.00 65.35 ? 189 PRO A CB 1 ATOM 1471 C CG . PRO A 1 208 ? 26.338 35.738 -9.609 1.00 75.29 ? 189 PRO A CG 1 ATOM 1472 C CD . PRO A 1 208 ? 25.641 35.076 -10.785 1.00 77.50 ? 189 PRO A CD 1 ATOM 1473 N N . GLU A 1 209 ? 23.321 34.601 -8.254 1.00 58.25 ? 190 GLU A N 1 ATOM 1474 C CA . GLU A 1 209 ? 22.235 35.059 -7.400 1.00 47.60 ? 190 GLU A CA 1 ATOM 1475 C C . GLU A 1 209 ? 21.222 33.944 -7.137 1.00 41.56 ? 190 GLU A C 1 ATOM 1476 O O . GLU A 1 209 ? 21.114 32.996 -7.917 1.00 47.43 ? 190 GLU A O 1 ATOM 1477 C CB . GLU A 1 209 ? 21.524 36.212 -8.101 1.00 61.41 ? 190 GLU A CB 1 ATOM 1478 C CG . GLU A 1 209 ? 22.469 37.226 -8.742 1.00 62.63 ? 190 GLU A CG 1 ATOM 1479 C CD . GLU A 1 209 ? 23.054 38.185 -7.720 1.00 73.10 ? 190 GLU A CD 1 ATOM 1480 O OE1 . GLU A 1 209 ? 22.746 38.018 -6.511 1.00 72.31 ? 190 GLU A OE1 1 ATOM 1481 O OE2 . GLU A 1 209 ? 23.810 39.103 -8.122 1.00 73.99 ? 190 GLU A OE2 1 ATOM 1482 N N . ALA A 1 210 ? 20.473 34.059 -6.046 1.00 35.74 ? 191 ALA A N 1 ATOM 1483 C CA . ALA A 1 210 ? 19.483 33.045 -5.694 1.00 32.52 ? 191 ALA A CA 1 ATOM 1484 C C . ALA A 1 210 ? 18.116 33.462 -6.194 1.00 31.01 ? 191 ALA A C 1 ATOM 1485 O O . ALA A 1 210 ? 17.791 34.654 -6.180 1.00 27.43 ? 191 ALA A O 1 ATOM 1486 C CB . ALA A 1 210 ? 19.447 32.851 -4.203 1.00 24.47 ? 191 ALA A CB 1 ATOM 1487 N N . TYR A 1 211 ? 17.314 32.484 -6.620 1.00 24.20 ? 192 TYR A N 1 ATOM 1488 C CA . TYR A 1 211 ? 15.943 32.759 -7.060 1.00 26.29 ? 192 TYR A CA 1 ATOM 1489 C C . TYR A 1 211 ? 14.941 32.072 -6.157 1.00 24.86 ? 192 TYR A C 1 ATOM 1490 O O . TYR A 1 211 ? 14.955 30.858 -6.044 1.00 28.54 ? 192 TYR A O 1 ATOM 1491 C CB . TYR A 1 211 ? 15.730 32.332 -8.521 1.00 27.11 ? 192 TYR A CB 1 ATOM 1492 C CG . TYR A 1 211 ? 16.460 33.212 -9.502 1.00 25.60 ? 192 TYR A CG 1 ATOM 1493 C CD1 . TYR A 1 211 ? 17.828 33.077 -9.689 1.00 29.63 ? 192 TYR A CD1 1 ATOM 1494 C CD2 . TYR A 1 211 ? 15.788 34.194 -10.231 1.00 29.19 ? 192 TYR A CD2 1 ATOM 1495 C CE1 . TYR A 1 211 ? 18.519 33.894 -10.577 1.00 40.58 ? 192 TYR A CE1 1 ATOM 1496 C CE2 . TYR A 1 211 ? 16.471 35.025 -11.130 1.00 32.04 ? 192 TYR A CE2 1 ATOM 1497 C CZ . TYR A 1 211 ? 17.838 34.863 -11.299 1.00 39.41 ? 192 TYR A CZ 1 ATOM 1498 O OH . TYR A 1 211 ? 18.538 35.660 -12.178 1.00 45.92 ? 192 TYR A OH 1 ATOM 1499 N N . GLU A 1 212 ? 14.061 32.841 -5.522 1.00 24.68 ? 193 GLU A N 1 ATOM 1500 C CA . GLU A 1 212 ? 13.031 32.245 -4.672 1.00 23.94 ? 193 GLU A CA 1 ATOM 1501 C C . GLU A 1 212 ? 11.833 31.678 -5.460 1.00 20.64 ? 193 GLU A C 1 ATOM 1502 O O . GLU A 1 212 ? 11.416 32.237 -6.477 1.00 25.00 ? 193 GLU A O 1 ATOM 1503 C CB . GLU A 1 212 ? 12.553 33.253 -3.622 1.00 21.49 ? 193 GLU A CB 1 ATOM 1504 C CG . GLU A 1 212 ? 13.655 33.786 -2.739 1.00 27.48 ? 193 GLU A CG 1 ATOM 1505 C CD . GLU A 1 212 ? 13.133 34.644 -1.589 1.00 36.68 ? 193 GLU A CD 1 ATOM 1506 O OE1 . GLU A 1 212 ? 11.905 34.795 -1.477 1.00 41.62 ? 193 GLU A OE1 1 ATOM 1507 O OE2 . GLU A 1 212 ? 13.946 35.172 -0.793 1.00 48.40 ? 193 GLU A OE2 1 ATOM 1508 N N . ASP A 1 213 ? 11.287 30.572 -4.971 1.00 18.79 ? 194 ASP A N 1 ATOM 1509 C CA . ASP A 1 213 ? 10.006 30.051 -5.445 1.00 19.60 ? 194 ASP A CA 1 ATOM 1510 C C . ASP A 1 213 ? 9.164 29.442 -4.319 1.00 24.25 ? 194 ASP A C 1 ATOM 1511 O O . ASP A 1 213 ? 9.658 29.162 -3.220 1.00 26.33 ? 194 ASP A O 1 ATOM 1512 C CB . ASP A 1 213 ? 10.205 29.007 -6.529 1.00 22.81 ? 194 ASP A CB 1 ATOM 1513 C CG . ASP A 1 213 ? 11.125 27.869 -6.083 1.00 50.37 ? 194 ASP A CG 1 ATOM 1514 O OD1 . ASP A 1 213 ? 10.634 26.906 -5.418 1.00 48.39 ? 194 ASP A OD1 1 ATOM 1515 O OD2 . ASP A 1 213 ? 12.345 27.940 -6.406 1.00 57.80 ? 194 ASP A OD2 1 ATOM 1516 N N . VAL A 1 214 ? 7.881 29.247 -4.609 1.00 24.88 ? 195 VAL A N 1 ATOM 1517 C CA . VAL A 1 214 ? 6.980 28.542 -3.707 1.00 27.38 ? 195 VAL A CA 1 ATOM 1518 C C . VAL A 1 214 ? 6.561 27.203 -4.305 1.00 24.01 ? 195 VAL A C 1 ATOM 1519 O O . VAL A 1 214 ? 6.187 27.132 -5.479 1.00 23.18 ? 195 VAL A O 1 ATOM 1520 C CB . VAL A 1 214 ? 5.749 29.388 -3.370 1.00 18.70 ? 195 VAL A CB 1 ATOM 1521 C CG1 . VAL A 1 214 ? 4.755 28.577 -2.565 1.00 20.97 ? 195 VAL A CG1 1 ATOM 1522 C CG2 . VAL A 1 214 ? 6.184 30.600 -2.583 1.00 25.54 ? 195 VAL A CG2 1 ATOM 1523 N N . GLU A 1 215 ? 6.665 26.145 -3.500 1.00 24.49 ? 196 GLU A N 1 ATOM 1524 C CA . GLU A 1 215 ? 6.306 24.798 -3.930 1.00 29.30 ? 196 GLU A CA 1 ATOM 1525 C C . GLU A 1 215 ? 5.005 24.438 -3.243 1.00 28.71 ? 196 GLU A C 1 ATOM 1526 O O . GLU A 1 215 ? 4.917 24.459 -2.007 1.00 28.52 ? 196 GLU A O 1 ATOM 1527 C CB . GLU A 1 215 ? 7.393 23.792 -3.534 1.00 37.47 ? 196 GLU A CB 1 ATOM 1528 C CG . GLU A 1 215 ? 7.843 22.860 -4.649 1.00 45.44 ? 196 GLU A CG 1 ATOM 1529 C CD . GLU A 1 215 ? 9.004 21.933 -4.232 1.00 70.92 ? 196 GLU A CD 1 ATOM 1530 O OE1 . GLU A 1 215 ? 8.907 21.287 -3.154 1.00 61.52 ? 196 GLU A OE1 1 ATOM 1531 O OE2 . GLU A 1 215 ? 10.010 21.853 -4.991 1.00 78.47 ? 196 GLU A OE2 1 ATOM 1532 N N . VAL A 1 216 ? 3.985 24.125 -4.035 1.00 26.71 ? 197 VAL A N 1 ATOM 1533 C CA . VAL A 1 216 ? 2.682 23.781 -3.473 1.00 27.09 ? 197 VAL A CA 1 ATOM 1534 C C . VAL A 1 216 ? 2.379 22.311 -3.691 1.00 24.39 ? 197 VAL A C 1 ATOM 1535 O O . VAL A 1 216 ? 2.264 21.874 -4.827 1.00 27.05 ? 197 VAL A O 1 ATOM 1536 C CB . VAL A 1 216 ? 1.556 24.642 -4.061 1.00 24.62 ? 197 VAL A CB 1 ATOM 1537 C CG1 . VAL A 1 216 ? 0.224 24.160 -3.538 1.00 20.89 ? 197 VAL A CG1 1 ATOM 1538 C CG2 . VAL A 1 216 ? 1.768 26.118 -3.695 1.00 20.98 ? 197 VAL A CG2 1 ATOM 1539 N N . SER A 1 217 ? 2.272 21.553 -2.599 1.00 28.36 ? 198 SER A N 1 ATOM 1540 C CA . SER A 1 217 ? 2.032 20.103 -2.670 1.00 30.17 ? 198 SER A CA 1 ATOM 1541 C C . SER A 1 217 ? 0.547 19.763 -2.557 1.00 27.31 ? 198 SER A C 1 ATOM 1542 O O . SER A 1 217 ? -0.107 20.052 -1.548 1.00 25.18 ? 198 SER A O 1 ATOM 1543 C CB . SER A 1 217 ? 2.820 19.361 -1.593 1.00 25.58 ? 198 SER A CB 1 ATOM 1544 O OG . SER A 1 217 ? 4.194 19.694 -1.669 1.00 30.96 ? 198 SER A OG 1 ATOM 1545 N N . LEU A 1 218 ? 0.019 19.147 -3.603 1.00 21.78 ? 199 LEU A N 1 ATOM 1546 C CA . LEU A 1 218 ? -1.400 18.869 -3.663 1.00 23.88 ? 199 LEU A CA 1 ATOM 1547 C C . LEU A 1 218 ? -1.632 17.379 -3.533 1.00 28.20 ? 199 LEU A C 1 ATOM 1548 O O . LEU A 1 218 ? -1.302 16.601 -4.438 1.00 33.18 ? 199 LEU A O 1 ATOM 1549 C CB . LEU A 1 218 ? -1.978 19.389 -4.978 1.00 24.93 ? 199 LEU A CB 1 ATOM 1550 C CG . LEU A 1 218 ? -3.384 18.888 -5.281 1.00 21.63 ? 199 LEU A CG 1 ATOM 1551 C CD1 . LEU A 1 218 ? -4.346 19.388 -4.222 1.00 24.82 ? 199 LEU A CD1 1 ATOM 1552 C CD2 . LEU A 1 218 ? -3.816 19.314 -6.673 1.00 23.75 ? 199 LEU A CD2 1 ATOM 1553 N N . ASN A 1 219 ? -2.192 16.968 -2.404 1.00 25.96 ? 200 ASN A N 1 ATOM 1554 C CA . ASN A 1 219 ? -2.471 15.548 -2.202 1.00 32.84 ? 200 ASN A CA 1 ATOM 1555 C C . ASN A 1 219 ? -3.933 15.220 -2.532 1.00 25.77 ? 200 ASN A C 1 ATOM 1556 O O . ASN A 1 219 ? -4.847 15.727 -1.885 1.00 31.75 ? 200 ASN A O 1 ATOM 1557 C CB . ASN A 1 219 ? -2.088 15.139 -0.777 1.00 34.77 ? 200 ASN A CB 1 ATOM 1558 C CG . ASN A 1 219 ? -2.256 13.651 -0.532 1.00 38.45 ? 200 ASN A CG 1 ATOM 1559 O OD1 . ASN A 1 219 ? -2.759 13.240 0.522 1.00 48.50 ? 200 ASN A OD1 1 ATOM 1560 N ND2 . ASN A 1 219 ? -1.845 12.831 -1.508 1.00 32.19 ? 200 ASN A ND2 1 ATOM 1561 N N . PHE A 1 220 ? -4.156 14.406 -3.558 1.00 19.59 ? 201 PHE A N 1 ATOM 1562 C CA . PHE A 1 220 ? -5.522 14.153 -4.045 1.00 23.54 ? 201 PHE A CA 1 ATOM 1563 C C . PHE A 1 220 ? -5.684 12.733 -4.553 1.00 25.01 ? 201 PHE A C 1 ATOM 1564 O O . PHE A 1 220 ? -4.704 12.072 -4.892 1.00 28.31 ? 201 PHE A O 1 ATOM 1565 C CB . PHE A 1 220 ? -5.865 15.103 -5.185 1.00 22.63 ? 201 PHE A CB 1 ATOM 1566 C CG . PHE A 1 220 ? -5.137 14.797 -6.464 1.00 21.02 ? 201 PHE A CG 1 ATOM 1567 C CD1 . PHE A 1 220 ? -3.756 14.972 -6.558 1.00 26.96 ? 201 PHE A CD1 1 ATOM 1568 C CD2 . PHE A 1 220 ? -5.828 14.338 -7.581 1.00 23.09 ? 201 PHE A CD2 1 ATOM 1569 C CE1 . PHE A 1 220 ? -3.072 14.681 -7.749 1.00 30.38 ? 201 PHE A CE1 1 ATOM 1570 C CE2 . PHE A 1 220 ? -5.154 14.049 -8.786 1.00 23.17 ? 201 PHE A CE2 1 ATOM 1571 C CZ . PHE A 1 220 ? -3.779 14.213 -8.867 1.00 24.41 ? 201 PHE A CZ 1 ATOM 1572 N N . ARG A 1 221 ? -6.922 12.261 -4.620 1.00 27.09 ? 202 ARG A N 1 ATOM 1573 C CA . ARG A 1 221 ? -7.197 10.933 -5.198 1.00 32.07 ? 202 ARG A CA 1 ATOM 1574 C C . ARG A 1 221 ? -8.528 10.891 -5.933 1.00 34.66 ? 202 ARG A C 1 ATOM 1575 O O . ARG A 1 221 ? -9.346 11.811 -5.817 1.00 34.85 ? 202 ARG A O 1 ATOM 1576 C CB . ARG A 1 221 ? -7.202 9.843 -4.124 1.00 37.15 ? 202 ARG A CB 1 ATOM 1577 C CG . ARG A 1 221 ? -8.262 10.068 -3.062 1.00 37.86 ? 202 ARG A CG 1 ATOM 1578 C CD . ARG A 1 221 ? -8.808 8.769 -2.499 1.00 38.65 ? 202 ARG A CD 1 ATOM 1579 N NE . ARG A 1 221 ? -9.809 9.054 -1.474 1.00 47.47 ? 202 ARG A NE 1 ATOM 1580 C CZ . ARG A 1 221 ? -9.594 8.951 -0.168 1.00 42.63 ? 202 ARG A CZ 1 ATOM 1581 N NH1 . ARG A 1 221 ? -8.415 8.528 0.273 1.00 35.85 ? 202 ARG A NH1 1 ATOM 1582 N NH2 . ARG A 1 221 ? -10.562 9.258 0.691 1.00 38.29 ? 202 ARG A NH2 1 ATOM 1583 N N . LYS A 1 222 ? -8.741 9.807 -6.678 1.00 37.25 ? 203 LYS A N 1 ATOM 1584 C CA . LYS A 1 222 ? -10.022 9.545 -7.334 1.00 33.23 ? 203 LYS A CA 1 ATOM 1585 C C . LYS A 1 222 ? -11.085 9.137 -6.309 1.00 36.72 ? 203 LYS A C 1 ATOM 1586 O O . LYS A 1 222 ? -10.791 8.428 -5.347 1.00 41.59 ? 203 LYS A O 1 ATOM 1587 C CB . LYS A 1 222 ? -9.857 8.440 -8.362 1.00 32.91 ? 203 LYS A CB 1 ATOM 1588 C CG . LYS A 1 222 ? -11.090 8.194 -9.206 1.00 40.40 ? 203 LYS A CG 1 ATOM 1589 C CD . LYS A 1 222 ? -10.777 7.160 -10.277 1.00 49.08 ? 203 LYS A CD 1 ATOM 1590 C CE . LYS A 1 222 ? -11.963 6.903 -11.184 1.00 60.76 ? 203 LYS A CE 1 ATOM 1591 N NZ . LYS A 1 222 ? -11.618 5.862 -12.195 1.00 67.17 ? 203 LYS A NZ 1 ATOM 1592 N N . LYS A 1 223 ? -12.312 9.602 -6.506 1.00 33.63 ? 204 LYS A N 1 ATOM 1593 C CA . LYS A 1 223 ? -13.409 9.281 -5.599 1.00 40.89 ? 204 LYS A CA 1 ATOM 1594 C C . LYS A 1 223 ? -13.887 7.822 -5.733 1.00 50.14 ? 204 LYS A C 1 ATOM 1595 O O . LYS A 1 223 ? -13.782 7.207 -6.800 1.00 51.92 ? 204 LYS A O 1 ATOM 1596 C CB . LYS A 1 223 ? -14.584 10.213 -5.864 1.00 41.27 ? 204 LYS A CB 1 ATOM 1597 C CG . LYS A 1 223 ? -14.443 11.623 -5.326 1.00 35.66 ? 204 LYS A CG 1 ATOM 1598 C CD . LYS A 1 223 ? -15.579 12.482 -5.895 1.00 41.10 ? 204 LYS A CD 1 ATOM 1599 C CE . LYS A 1 223 ? -15.862 13.719 -5.061 1.00 41.56 ? 204 LYS A CE 1 ATOM 1600 N NZ . LYS A 1 223 ? -17.120 14.390 -5.500 1.00 41.47 ? 204 LYS A NZ 1 ATOM 1601 N N . LEU B 1 20 ? 21.330 57.600 -11.500 1.00 52.19 ? 1 LEU B N 1 ATOM 1602 C CA . LEU B 1 20 ? 20.339 56.830 -12.249 1.00 37.32 ? 1 LEU B CA 1 ATOM 1603 C C . LEU B 1 20 ? 19.658 55.772 -11.396 1.00 38.59 ? 1 LEU B C 1 ATOM 1604 O O . LEU B 1 20 ? 20.327 55.010 -10.696 1.00 45.73 ? 1 LEU B O 1 ATOM 1605 C CB . LEU B 1 20 ? 21.003 56.125 -13.418 1.00 37.76 ? 1 LEU B CB 1 ATOM 1606 C CG . LEU B 1 20 ? 21.365 56.970 -14.630 1.00 33.92 ? 1 LEU B CG 1 ATOM 1607 C CD1 . LEU B 1 20 ? 21.828 56.036 -15.732 1.00 33.53 ? 1 LEU B CD1 1 ATOM 1608 C CD2 . LEU B 1 20 ? 20.184 57.812 -15.078 1.00 29.38 ? 1 LEU B CD2 1 ATOM 1609 N N . ASP B 1 21 ? 18.331 55.719 -11.453 1.00 33.91 ? 2 ASP B N 1 ATOM 1610 C CA . ASP B 1 21 ? 17.604 54.621 -10.824 1.00 35.10 ? 2 ASP B CA 1 ATOM 1611 C C . ASP B 1 21 ? 16.964 53.789 -11.917 1.00 34.24 ? 2 ASP B C 1 ATOM 1612 O O . ASP B 1 21 ? 17.048 54.156 -13.099 1.00 28.55 ? 2 ASP B O 1 ATOM 1613 C CB . ASP B 1 21 ? 16.559 55.125 -9.819 1.00 43.16 ? 2 ASP B CB 1 ATOM 1614 C CG . ASP B 1 21 ? 15.737 56.300 -10.351 1.00 52.12 ? 2 ASP B CG 1 ATOM 1615 O OD1 . ASP B 1 21 ? 15.399 56.291 -11.557 1.00 51.14 ? 2 ASP B OD1 1 ATOM 1616 O OD2 . ASP B 1 21 ? 15.428 57.234 -9.563 1.00 65.32 ? 2 ASP B OD2 1 ATOM 1617 N N . ARG B 1 22 ? 16.343 52.673 -11.530 1.00 32.20 ? 3 ARG B N 1 ATOM 1618 C CA . ARG B 1 22 ? 15.705 51.792 -12.508 1.00 31.82 ? 3 ARG B CA 1 ATOM 1619 C C . ARG B 1 22 ? 14.706 52.530 -13.381 1.00 26.42 ? 3 ARG B C 1 ATOM 1620 O O . ARG B 1 22 ? 14.662 52.302 -14.593 1.00 23.20 ? 3 ARG B O 1 ATOM 1621 C CB . ARG B 1 22 ? 15.027 50.593 -11.846 1.00 30.55 ? 3 ARG B CB 1 ATOM 1622 C CG . ARG B 1 22 ? 15.973 49.496 -11.440 1.00 29.14 ? 3 ARG B CG 1 ATOM 1623 C CD . ARG B 1 22 ? 15.217 48.376 -10.778 1.00 32.99 ? 3 ARG B CD 1 ATOM 1624 N NE . ARG B 1 22 ? 16.131 47.311 -10.407 1.00 41.44 ? 3 ARG B NE 1 ATOM 1625 C CZ . ARG B 1 22 ? 16.813 47.297 -9.272 1.00 50.53 ? 3 ARG B CZ 1 ATOM 1626 N NH1 . ARG B 1 22 ? 16.669 48.291 -8.397 1.00 49.20 ? 3 ARG B NH1 1 ATOM 1627 N NH2 . ARG B 1 22 ? 17.636 46.291 -9.013 1.00 60.07 ? 3 ARG B NH2 1 ATOM 1628 N N . ALA B 1 23 ? 13.920 53.414 -12.767 1.00 26.31 ? 4 ALA B N 1 ATOM 1629 C CA . ALA B 1 23 ? 12.895 54.152 -13.501 1.00 23.11 ? 4 ALA B CA 1 ATOM 1630 C C . ALA B 1 23 ? 13.511 54.956 -14.655 1.00 28.93 ? 4 ALA B C 1 ATOM 1631 O O . ALA B 1 23 ? 13.008 54.946 -15.788 1.00 22.90 ? 4 ALA B O 1 ATOM 1632 C CB . ALA B 1 23 ? 12.125 55.046 -12.570 1.00 20.48 ? 4 ALA B CB 1 ATOM 1633 N N . ASP B 1 24 ? 14.618 55.630 -14.356 1.00 31.73 ? 5 ASP B N 1 ATOM 1634 C CA . ASP B 1 24 ? 15.359 56.407 -15.346 1.00 32.57 ? 5 ASP B CA 1 ATOM 1635 C C . ASP B 1 24 ? 15.935 55.558 -16.517 1.00 30.57 ? 5 ASP B C 1 ATOM 1636 O O . ASP B 1 24 ? 15.792 55.915 -17.699 1.00 25.49 ? 5 ASP B O 1 ATOM 1637 C CB . ASP B 1 24 ? 16.467 57.213 -14.641 1.00 36.39 ? 5 ASP B CB 1 ATOM 1638 C CG . ASP B 1 24 ? 15.914 58.389 -13.811 1.00 51.15 ? 5 ASP B CG 1 ATOM 1639 O OD1 . ASP B 1 24 ? 14.862 58.954 -14.199 1.00 55.21 ? 5 ASP B OD1 1 ATOM 1640 O OD2 . ASP B 1 24 ? 16.534 58.754 -12.777 1.00 49.32 ? 5 ASP B OD2 1 ATOM 1641 N N . ILE B 1 25 ? 16.569 54.436 -16.180 1.00 26.83 ? 6 ILE B N 1 ATOM 1642 C CA . ILE B 1 25 ? 17.155 53.548 -17.183 1.00 23.00 ? 6 ILE B CA 1 ATOM 1643 C C . ILE B 1 25 ? 16.114 52.963 -18.144 1.00 26.30 ? 6 ILE B C 1 ATOM 1644 O O . ILE B 1 25 ? 16.317 52.963 -19.365 1.00 24.46 ? 6 ILE B O 1 ATOM 1645 C CB . ILE B 1 25 ? 17.925 52.394 -16.528 1.00 22.68 ? 6 ILE B CB 1 ATOM 1646 C CG1 . ILE B 1 25 ? 19.096 52.933 -15.700 1.00 26.56 ? 6 ILE B CG1 1 ATOM 1647 C CG2 . ILE B 1 25 ? 18.376 51.375 -17.570 1.00 17.53 ? 6 ILE B CG2 1 ATOM 1648 C CD1 . ILE B 1 25 ? 19.706 51.887 -14.747 1.00 31.36 ? 6 ILE B CD1 1 ATOM 1649 N N . LEU B 1 26 ? 15.005 52.466 -17.591 1.00 24.33 ? 7 LEU B N 1 ATOM 1650 C CA . LEU B 1 26 ? 13.951 51.855 -18.395 1.00 15.63 ? 7 LEU B CA 1 ATOM 1651 C C . LEU B 1 26 ? 13.298 52.910 -19.265 1.00 20.02 ? 7 LEU B C 1 ATOM 1652 O O . LEU B 1 26 ? 12.884 52.632 -20.390 1.00 20.43 ? 7 LEU B O 1 ATOM 1653 C CB . LEU B 1 26 ? 12.938 51.137 -17.506 1.00 18.65 ? 7 LEU B CB 1 ATOM 1654 C CG . LEU B 1 26 ? 13.545 49.909 -16.796 1.00 22.51 ? 7 LEU B CG 1 ATOM 1655 C CD1 . LEU B 1 26 ? 12.779 49.483 -15.563 1.00 19.36 ? 7 LEU B CD1 1 ATOM 1656 C CD2 . LEU B 1 26 ? 13.659 48.735 -17.753 1.00 22.09 ? 7 LEU B CD2 1 ATOM 1657 N N . TYR B 1 27 ? 13.240 54.137 -18.753 1.00 24.20 ? 8 TYR B N 1 ATOM 1658 C CA . TYR B 1 27 ? 12.723 55.262 -19.526 1.00 19.99 ? 8 TYR B CA 1 ATOM 1659 C C . TYR B 1 27 ? 13.590 55.530 -20.732 1.00 21.45 ? 8 TYR B C 1 ATOM 1660 O O . TYR B 1 27 ? 13.094 55.540 -21.854 1.00 22.59 ? 8 TYR B O 1 ATOM 1661 C CB . TYR B 1 27 ? 12.634 56.513 -18.673 1.00 22.21 ? 8 TYR B CB 1 ATOM 1662 C CG . TYR B 1 27 ? 12.116 57.714 -19.425 1.00 33.26 ? 8 TYR B CG 1 ATOM 1663 C CD1 . TYR B 1 27 ? 10.760 57.861 -19.692 1.00 37.59 ? 8 TYR B CD1 1 ATOM 1664 C CD2 . TYR B 1 27 ? 12.980 58.713 -19.861 1.00 36.66 ? 8 TYR B CD2 1 ATOM 1665 C CE1 . TYR B 1 27 ? 10.278 58.969 -20.378 1.00 33.84 ? 8 TYR B CE1 1 ATOM 1666 C CE2 . TYR B 1 27 ? 12.511 59.818 -20.543 1.00 35.10 ? 8 TYR B CE2 1 ATOM 1667 C CZ . TYR B 1 27 ? 11.160 59.942 -20.799 1.00 39.96 ? 8 TYR B CZ 1 ATOM 1668 O OH . TYR B 1 27 ? 10.695 61.053 -21.481 1.00 48.61 ? 8 TYR B OH 1 ATOM 1669 N N . ASN B 1 28 ? 14.883 55.749 -20.501 1.00 21.31 ? 9 ASN B N 1 ATOM 1670 C CA . ASN B 1 28 ? 15.827 55.923 -21.607 1.00 21.46 ? 9 ASN B CA 1 ATOM 1671 C C . ASN B 1 28 ? 15.776 54.785 -22.628 1.00 25.01 ? 9 ASN B C 1 ATOM 1672 O O . ASN B 1 28 ? 15.788 55.033 -23.824 1.00 30.66 ? 9 ASN B O 1 ATOM 1673 C CB . ASN B 1 28 ? 17.261 56.127 -21.103 1.00 19.76 ? 9 ASN B CB 1 ATOM 1674 C CG . ASN B 1 28 ? 17.401 57.350 -20.212 1.00 22.59 ? 9 ASN B CG 1 ATOM 1675 O OD1 . ASN B 1 28 ? 16.634 58.303 -20.325 1.00 27.93 ? 9 ASN B OD1 1 ATOM 1676 N ND2 . ASN B 1 28 ? 18.383 57.325 -19.315 1.00 22.92 ? 9 ASN B ND2 1 ATOM 1677 N N . ILE B 1 29 ? 15.714 53.542 -22.158 1.00 23.43 ? 10 ILE B N 1 ATOM 1678 C CA . ILE B 1 29 ? 15.639 52.400 -23.062 1.00 22.84 ? 10 ILE B CA 1 ATOM 1679 C C . ILE B 1 29 ? 14.377 52.417 -23.922 1.00 27.55 ? 10 ILE B C 1 ATOM 1680 O O . ILE B 1 29 ? 14.448 52.196 -25.122 1.00 27.53 ? 10 ILE B O 1 ATOM 1681 C CB . ILE B 1 29 ? 15.754 51.057 -22.316 1.00 25.28 ? 10 ILE B CB 1 ATOM 1682 C CG1 . ILE B 1 29 ? 17.166 50.914 -21.738 1.00 21.93 ? 10 ILE B CG1 1 ATOM 1683 C CG2 . ILE B 1 29 ? 15.409 49.889 -23.251 1.00 23.31 ? 10 ILE B CG2 1 ATOM 1684 C CD1 . ILE B 1 29 ? 17.427 49.624 -20.990 1.00 16.17 ? 10 ILE B CD1 1 ATOM 1685 N N . ARG B 1 30 ? 13.230 52.712 -23.314 1.00 30.61 ? 11 ARG B N 1 ATOM 1686 C CA . ARG B 1 30 ? 11.981 52.830 -24.069 1.00 27.58 ? 11 ARG B CA 1 ATOM 1687 C C . ARG B 1 30 ? 12.010 53.924 -25.149 1.00 32.65 ? 11 ARG B C 1 ATOM 1688 O O . ARG B 1 30 ? 11.397 53.774 -26.197 1.00 37.79 ? 11 ARG B O 1 ATOM 1689 C CB . ARG B 1 30 ? 10.795 53.051 -23.141 1.00 23.76 ? 11 ARG B CB 1 ATOM 1690 C CG . ARG B 1 30 ? 9.608 52.239 -23.544 1.00 35.63 ? 11 ARG B CG 1 ATOM 1691 C CD . ARG B 1 30 ? 8.315 52.972 -23.286 1.00 57.87 ? 11 ARG B CD 1 ATOM 1692 N NE . ARG B 1 30 ? 7.249 52.418 -24.121 1.00 82.75 ? 11 ARG B NE 1 ATOM 1693 C CZ . ARG B 1 30 ? 5.999 52.872 -24.159 1.00 87.79 ? 11 ARG B CZ 1 ATOM 1694 N NH1 . ARG B 1 30 ? 5.632 53.901 -23.400 1.00 82.92 ? 11 ARG B NH1 1 ATOM 1695 N NH2 . ARG B 1 30 ? 5.116 52.290 -24.963 1.00 75.26 ? 11 ARG B NH2 1 ATOM 1696 N N . GLN B 1 31 ? 12.733 55.010 -24.903 1.00 33.29 ? 12 GLN B N 1 ATOM 1697 C CA . GLN B 1 31 ? 12.786 56.125 -25.850 1.00 30.16 ? 12 GLN B CA 1 ATOM 1698 C C . GLN B 1 31 ? 13.803 56.011 -27.000 1.00 32.48 ? 12 GLN B C 1 ATOM 1699 O O . GLN B 1 31 ? 13.624 56.658 -28.029 1.00 35.95 ? 12 GLN B O 1 ATOM 1700 C CB . GLN B 1 31 ? 13.066 57.428 -25.101 1.00 35.99 ? 12 GLN B CB 1 ATOM 1701 C CG . GLN B 1 31 ? 12.065 57.781 -24.012 1.00 41.91 ? 12 GLN B CG 1 ATOM 1702 C CD . GLN B 1 31 ? 10.696 58.118 -24.573 1.00 49.09 ? 12 GLN B CD 1 ATOM 1703 O OE1 . GLN B 1 31 ? 10.553 58.403 -25.764 1.00 53.17 ? 12 GLN B OE1 1 ATOM 1704 N NE2 . GLN B 1 31 ? 9.676 58.083 -23.713 1.00 49.71 ? 12 GLN B NE2 1 ATOM 1705 N N . THR B 1 32 ? 14.904 55.326 -26.792 1.00 30.18 ? 13 THR B N 1 ATOM 1706 C CA . THR B 1 32 ? 15.951 55.309 -27.771 1.00 32.78 ? 13 THR B CA 1 ATOM 1707 C C . THR B 1 32 ? 16.367 53.975 -28.347 1.00 37.81 ? 13 THR B C 1 ATOM 1708 O O . THR B 1 32 ? 17.245 53.919 -29.170 1.00 41.02 ? 13 THR B O 1 ATOM 1709 C CB . THR B 1 32 ? 17.202 55.981 -27.220 1.00 27.92 ? 13 THR B CB 1 ATOM 1710 O OG1 . THR B 1 32 ? 17.823 55.105 -26.305 1.00 40.29 ? 13 THR B OG1 1 ATOM 1711 C CG2 . THR B 1 32 ? 16.863 57.206 -26.519 1.00 21.53 ? 13 THR B CG2 1 ATOM 1712 N N . SER B 1 33 ? 15.734 52.904 -27.924 1.00 41.20 ? 14 SER B N 1 ATOM 1713 C CA . SER B 1 33 ? 16.192 51.536 -28.179 1.00 41.75 ? 14 SER B CA 1 ATOM 1714 C C . SER B 1 33 ? 16.266 51.029 -29.625 1.00 44.93 ? 14 SER B C 1 ATOM 1715 O O . SER B 1 33 ? 17.185 50.299 -29.959 1.00 31.52 ? 14 SER B O 1 ATOM 1716 C CB . SER B 1 33 ? 15.469 50.576 -27.236 1.00 35.35 ? 14 SER B CB 1 ATOM 1717 O OG . SER B 1 33 ? 14.940 49.433 -27.844 1.00 40.68 ? 14 SER B OG 1 ATOM 1718 N N . ARG B 1 34 ? 15.322 51.419 -30.477 1.00 36.44 ? 15 ARG B N 1 ATOM 1719 C CA . ARG B 1 34 ? 15.311 50.958 -31.863 1.00 34.35 ? 15 ARG B CA 1 ATOM 1720 C C . ARG B 1 34 ? 15.208 49.464 -32.060 1.00 31.35 ? 15 ARG B C 1 ATOM 1721 O O . ARG B 1 34 ? 16.121 48.827 -32.465 1.00 32.52 ? 15 ARG B O 1 ATOM 1722 C CB . ARG B 1 34 ? 16.495 51.492 -32.671 1.00 38.13 ? 15 ARG B CB 1 ATOM 1723 C CG . ARG B 1 34 ? 16.650 52.994 -32.818 1.00 41.60 ? 15 ARG B CG 1 ATOM 1724 C CD . ARG B 1 34 ? 15.485 53.760 -33.418 1.00 41.98 ? 15 ARG B CD 1 ATOM 1725 N NE . ARG B 1 34 ? 14.889 53.239 -34.651 1.00 58.01 ? 15 ARG B NE 1 ATOM 1726 C CZ . ARG B 1 34 ? 15.267 53.507 -35.898 1.00 46.56 ? 15 ARG B CZ 1 ATOM 1727 N NH1 . ARG B 1 34 ? 16.296 54.260 -36.158 1.00 44.14 ? 15 ARG B NH1 1 ATOM 1728 N NH2 . ARG B 1 34 ? 14.597 52.975 -36.883 1.00 34.06 ? 15 ARG B NH2 1 ATOM 1729 N N . PRO B 1 35 ? 13.980 48.920 -31.757 1.00 27.48 ? 16 PRO B N 1 ATOM 1730 C CA . PRO B 1 35 ? 13.875 47.468 -31.865 1.00 27.74 ? 16 PRO B CA 1 ATOM 1731 C C . PRO B 1 35 ? 14.006 46.843 -33.245 1.00 22.91 ? 16 PRO B C 1 ATOM 1732 O O . PRO B 1 35 ? 14.044 45.654 -33.356 1.00 22.86 ? 16 PRO B O 1 ATOM 1733 C CB . PRO B 1 35 ? 12.490 47.177 -31.331 1.00 23.42 ? 16 PRO B CB 1 ATOM 1734 C CG . PRO B 1 35 ? 12.123 48.302 -30.540 1.00 20.87 ? 16 PRO B CG 1 ATOM 1735 C CD . PRO B 1 35 ? 12.617 49.420 -31.296 1.00 28.35 ? 16 PRO B CD 1 ATOM 1736 N N . ASP B 1 36 ? 13.937 47.634 -34.281 1.00 22.68 ? 17 ASP B N 1 ATOM 1737 C CA . ASP B 1 36 ? 14.056 47.110 -35.613 1.00 23.70 ? 17 ASP B CA 1 ATOM 1738 C C . ASP B 1 36 ? 15.428 47.183 -36.198 1.00 24.82 ? 17 ASP B C 1 ATOM 1739 O O . ASP B 1 36 ? 15.668 46.691 -37.250 1.00 28.17 ? 17 ASP B O 1 ATOM 1740 C CB . ASP B 1 36 ? 13.025 47.741 -36.501 1.00 26.84 ? 17 ASP B CB 1 ATOM 1741 C CG . ASP B 1 36 ? 12.976 49.207 -36.370 1.00 54.47 ? 17 ASP B CG 1 ATOM 1742 O OD1 . ASP B 1 36 ? 13.140 49.745 -35.260 1.00 48.98 ? 17 ASP B OD1 1 ATOM 1743 O OD2 . ASP B 1 36 ? 12.765 49.848 -37.404 1.00 56.25 ? 17 ASP B OD2 1 ATOM 1744 N N . VAL B 1 37 ? 16.338 47.761 -35.460 1.00 23.08 ? 18 VAL B N 1 ATOM 1745 C CA . VAL B 1 37 ? 17.712 47.952 -35.931 1.00 25.83 ? 18 VAL B CA 1 ATOM 1746 C C . VAL B 1 37 ? 18.714 46.997 -35.298 1.00 23.87 ? 18 VAL B C 1 ATOM 1747 O O . VAL B 1 37 ? 19.003 47.098 -34.103 1.00 23.85 ? 18 VAL B O 1 ATOM 1748 C CB . VAL B 1 37 ? 18.236 49.373 -35.637 1.00 27.94 ? 18 VAL B CB 1 ATOM 1749 C CG1 . VAL B 1 37 ? 19.700 49.499 -36.090 1.00 23.05 ? 18 VAL B CG1 1 ATOM 1750 C CG2 . VAL B 1 37 ? 17.355 50.415 -36.292 1.00 28.16 ? 18 VAL B CG2 1 ATOM 1751 N N . ILE B 1 38 ? 19.257 46.096 -36.113 1.00 25.97 ? 19 ILE B N 1 ATOM 1752 C CA . ILE B 1 38 ? 20.318 45.182 -35.688 1.00 25.05 ? 19 ILE B CA 1 ATOM 1753 C C . ILE B 1 38 ? 21.561 45.935 -35.183 1.00 26.76 ? 19 ILE B C 1 ATOM 1754 O O . ILE B 1 38 ? 22.085 46.829 -35.859 1.00 30.03 ? 19 ILE B O 1 ATOM 1755 C CB . ILE B 1 38 ? 20.656 44.179 -36.840 1.00 25.14 ? 19 ILE B CB 1 ATOM 1756 C CG1 . ILE B 1 38 ? 21.702 43.140 -36.430 1.00 21.56 ? 19 ILE B CG1 1 ATOM 1757 C CG2 . ILE B 1 38 ? 21.070 44.907 -38.107 1.00 25.40 ? 19 ILE B CG2 1 ATOM 1758 C CD1 . ILE B 1 38 ? 21.771 41.960 -37.407 1.00 21.95 ? 19 ILE B CD1 1 ATOM 1759 N N . PRO B 1 39 ? 22.022 45.586 -33.973 1.00 26.12 ? 20 PRO B N 1 ATOM 1760 C CA . PRO B 1 39 ? 23.134 46.313 -33.344 1.00 26.61 ? 20 PRO B CA 1 ATOM 1761 C C . PRO B 1 39 ? 24.515 45.824 -33.828 1.00 34.34 ? 20 PRO B C 1 ATOM 1762 O O . PRO B 1 39 ? 25.316 45.307 -33.031 1.00 39.16 ? 20 PRO B O 1 ATOM 1763 C CB . PRO B 1 39 ? 22.922 46.036 -31.849 1.00 25.22 ? 20 PRO B CB 1 ATOM 1764 C CG . PRO B 1 39 ? 22.278 44.654 -31.823 1.00 24.61 ? 20 PRO B CG 1 ATOM 1765 C CD . PRO B 1 39 ? 21.446 44.554 -33.086 1.00 20.91 ? 20 PRO B CD 1 ATOM 1766 N N . THR B 1 40 ? 24.783 45.986 -35.127 1.00 33.97 ? 21 THR B N 1 ATOM 1767 C CA . THR B 1 40 ? 26.100 45.666 -35.683 1.00 34.57 ? 21 THR B CA 1 ATOM 1768 C C . THR B 1 40 ? 27.123 46.694 -35.221 1.00 44.41 ? 21 THR B C 1 ATOM 1769 O O . THR B 1 40 ? 26.771 47.842 -34.921 1.00 41.25 ? 21 THR B O 1 ATOM 1770 C CB . THR B 1 40 ? 26.077 45.608 -37.219 1.00 39.11 ? 21 THR B CB 1 ATOM 1771 O OG1 . THR B 1 40 ? 25.530 46.828 -37.732 1.00 44.79 ? 21 THR B OG1 1 ATOM 1772 C CG2 . THR B 1 40 ? 25.218 44.433 -37.701 1.00 39.39 ? 21 THR B CG2 1 ATOM 1773 N N . GLN B 1 41 ? 28.383 46.267 -35.148 1.00 56.69 ? 22 GLN B N 1 ATOM 1774 C CA . GLN B 1 41 ? 29.492 47.140 -34.746 1.00 58.90 ? 22 GLN B CA 1 ATOM 1775 C C . GLN B 1 41 ? 30.579 47.140 -35.811 1.00 60.61 ? 22 GLN B C 1 ATOM 1776 O O . GLN B 1 41 ? 31.476 46.302 -35.777 1.00 72.38 ? 22 GLN B O 1 ATOM 1777 C CB . GLN B 1 41 ? 30.106 46.675 -33.421 1.00 58.86 ? 22 GLN B CB 1 ATOM 1778 C CG . GLN B 1 41 ? 29.468 47.234 -32.163 1.00 68.32 ? 22 GLN B CG 1 ATOM 1779 C CD . GLN B 1 41 ? 30.198 46.792 -30.893 1.00 82.76 ? 22 GLN B CD 1 ATOM 1780 O OE1 . GLN B 1 41 ? 30.331 45.589 -30.616 1.00 80.05 ? 22 GLN B OE1 1 ATOM 1781 N NE2 . GLN B 1 41 ? 30.682 47.766 -30.120 1.00 71.89 ? 22 GLN B NE2 1 ATOM 1782 N N . ARG B 1 42 ? 30.669 48.200 -36.564 1.00 63.38 ? 23 ARG B N 1 ATOM 1783 C CA . ARG B 1 42 ? 31.791 48.293 -37.445 1.00 70.56 ? 23 ARG B CA 1 ATOM 1784 C C . ARG B 1 42 ? 31.785 47.111 -38.388 1.00 69.77 ? 23 ARG B C 1 ATOM 1785 O O . ARG B 1 42 ? 32.809 46.547 -38.690 1.00 70.76 ? 23 ARG B O 1 ATOM 1786 C CB . ARG B 1 42 ? 33.089 48.278 -36.644 1.00 72.78 ? 23 ARG B CB 1 ATOM 1787 C CG . ARG B 1 42 ? 33.274 49.334 -35.579 1.00 78.11 ? 23 ARG B CG 1 ATOM 1788 C CD . ARG B 1 42 ? 34.741 49.348 -35.168 1.00 91.82 ? 23 ARG B CD 1 ATOM 1789 N NE . ARG B 1 42 ? 35.002 49.481 -33.732 1.00 108.73 ? 23 ARG B NE 1 ATOM 1790 C CZ . ARG B 1 42 ? 35.523 50.561 -33.151 1.00 101.78 ? 23 ARG B CZ 1 ATOM 1791 N NH1 . ARG B 1 42 ? 35.834 51.621 -33.875 1.00 104.58 ? 23 ARG B NH1 1 ATOM 1792 N NH2 . ARG B 1 42 ? 35.736 50.583 -31.849 1.00 78.95 ? 23 ARG B NH2 1 ATOM 1793 N N . ASP B 1 43 ? 30.617 46.741 -38.872 1.00 71.02 ? 24 ASP B N 1 ATOM 1794 C CA . ASP B 1 43 ? 30.541 45.739 -39.917 1.00 77.87 ? 24 ASP B CA 1 ATOM 1795 C C . ASP B 1 43 ? 30.868 44.344 -39.485 1.00 66.70 ? 24 ASP B C 1 ATOM 1796 O O . ASP B 1 43 ? 31.307 43.528 -40.272 1.00 65.81 ? 24 ASP B O 1 ATOM 1797 C CB . ASP B 1 43 ? 31.471 46.116 -41.057 1.00 75.11 ? 24 ASP B CB 1 ATOM 1798 C CG . ASP B 1 43 ? 30.773 46.880 -42.134 1.00 84.94 ? 24 ASP B CG 1 ATOM 1799 O OD1 . ASP B 1 43 ? 29.877 47.666 -41.804 1.00 87.28 ? 24 ASP B OD1 1 ATOM 1800 O OD2 . ASP B 1 43 ? 31.120 46.688 -43.312 1.00 86.08 ? 24 ASP B OD2 1 ATOM 1801 N N . ARG B 1 44 ? 30.631 44.068 -38.228 1.00 56.07 ? 25 ARG B N 1 ATOM 1802 C CA . ARG B 1 44 ? 30.901 42.771 -37.711 1.00 50.56 ? 25 ARG B CA 1 ATOM 1803 C C . ARG B 1 44 ? 29.612 42.169 -37.340 1.00 40.64 ? 25 ARG B C 1 ATOM 1804 O O . ARG B 1 44 ? 28.681 42.860 -37.054 1.00 42.38 ? 25 ARG B O 1 ATOM 1805 C CB . ARG B 1 44 ? 31.776 42.880 -36.509 1.00 52.23 ? 25 ARG B CB 1 ATOM 1806 C CG . ARG B 1 44 ? 32.900 43.830 -36.747 1.00 64.51 ? 25 ARG B CG 1 ATOM 1807 C CD . ARG B 1 44 ? 33.970 43.653 -35.719 1.00 68.39 ? 25 ARG B CD 1 ATOM 1808 N NE . ARG B 1 44 ? 35.129 44.352 -36.189 1.00 86.11 ? 25 ARG B NE 1 ATOM 1809 C CZ . ARG B 1 44 ? 35.483 45.552 -35.780 1.00 85.03 ? 25 ARG B CZ 1 ATOM 1810 N NH1 . ARG B 1 44 ? 34.781 46.151 -34.828 1.00 74.70 ? 25 ARG B NH1 1 ATOM 1811 N NH2 . ARG B 1 44 ? 36.574 46.121 -36.291 1.00 84.85 ? 25 ARG B NH2 1 ATOM 1812 N N . PRO B 1 45 ? 29.581 40.798 -37.424 1.00 35.33 ? 26 PRO B N 1 ATOM 1813 C CA . PRO B 1 45 ? 28.305 40.201 -37.083 1.00 35.23 ? 26 PRO B CA 1 ATOM 1814 C C . PRO B 1 45 ? 27.949 40.366 -35.644 1.00 33.85 ? 26 PRO B C 1 ATOM 1815 O O . PRO B 1 45 ? 28.808 40.459 -34.828 1.00 33.97 ? 26 PRO B O 1 ATOM 1816 C CB . PRO B 1 45 ? 28.538 38.743 -37.316 1.00 39.46 ? 26 PRO B CB 1 ATOM 1817 C CG . PRO B 1 45 ? 29.556 38.681 -38.327 1.00 38.25 ? 26 PRO B CG 1 ATOM 1818 C CD . PRO B 1 45 ? 30.504 39.662 -37.846 1.00 35.73 ? 26 PRO B CD 1 ATOM 1819 N N . VAL B 1 46 ? 26.677 40.411 -35.331 1.00 28.94 ? 27 VAL B N 1 ATOM 1820 C CA . VAL B 1 46 ? 26.306 40.335 -33.934 1.00 26.84 ? 27 VAL B CA 1 ATOM 1821 C C . VAL B 1 46 ? 26.545 38.889 -33.521 1.00 28.23 ? 27 VAL B C 1 ATOM 1822 O O . VAL B 1 46 ? 26.050 37.966 -34.183 1.00 30.83 ? 27 VAL B O 1 ATOM 1823 C CB . VAL B 1 46 ? 24.827 40.672 -33.756 1.00 25.17 ? 27 VAL B CB 1 ATOM 1824 C CG1 . VAL B 1 46 ? 24.422 40.557 -32.285 1.00 24.95 ? 27 VAL B CG1 1 ATOM 1825 C CG2 . VAL B 1 46 ? 24.546 42.051 -34.278 1.00 20.93 ? 27 VAL B CG2 1 ATOM 1826 N N . ALA B 1 47 ? 27.310 38.664 -32.456 1.00 22.46 ? 28 ALA B N 1 ATOM 1827 C CA . ALA B 1 47 ? 27.552 37.281 -32.031 1.00 27.20 ? 28 ALA B CA 1 ATOM 1828 C C . ALA B 1 47 ? 26.448 36.796 -31.082 1.00 30.93 ? 28 ALA B C 1 ATOM 1829 O O . ALA B 1 47 ? 26.345 37.243 -29.940 1.00 33.04 ? 28 ALA B O 1 ATOM 1830 C CB . ALA B 1 47 ? 28.906 37.132 -31.394 1.00 22.94 ? 28 ALA B CB 1 ATOM 1831 N N . VAL B 1 48 ? 25.625 35.877 -31.558 1.00 25.42 ? 29 VAL B N 1 ATOM 1832 C CA . VAL B 1 48 ? 24.537 35.355 -30.753 1.00 26.73 ? 29 VAL B CA 1 ATOM 1833 C C . VAL B 1 48 ? 24.928 33.960 -30.254 1.00 29.59 ? 29 VAL B C 1 ATOM 1834 O O . VAL B 1 48 ? 25.335 33.105 -31.034 1.00 33.16 ? 29 VAL B O 1 ATOM 1835 C CB . VAL B 1 48 ? 23.216 35.265 -31.587 1.00 25.35 ? 29 VAL B CB 1 ATOM 1836 C CG1 . VAL B 1 48 ? 22.061 34.749 -30.752 1.00 16.97 ? 29 VAL B CG1 1 ATOM 1837 C CG2 . VAL B 1 48 ? 22.864 36.613 -32.201 1.00 22.10 ? 29 VAL B CG2 1 ATOM 1838 N N . SER B 1 49 ? 24.803 33.727 -28.955 1.00 29.13 ? 30 SER B N 1 ATOM 1839 C CA . SER B 1 49 ? 25.008 32.396 -28.399 1.00 25.31 ? 30 SER B CA 1 ATOM 1840 C C . SER B 1 49 ? 23.666 31.762 -28.123 1.00 24.05 ? 30 SER B C 1 ATOM 1841 O O . SER B 1 49 ? 22.769 32.411 -27.606 1.00 25.42 ? 30 SER B O 1 ATOM 1842 C CB . SER B 1 49 ? 25.770 32.485 -27.093 1.00 26.51 ? 30 SER B CB 1 ATOM 1843 O OG . SER B 1 49 ? 26.804 33.440 -27.204 1.00 36.69 ? 30 SER B OG 1 ATOM 1844 N N . VAL B 1 50 ? 23.539 30.484 -28.453 1.00 29.51 ? 31 VAL B N 1 ATOM 1845 C CA . VAL B 1 50 ? 22.301 29.758 -28.249 1.00 23.94 ? 31 VAL B CA 1 ATOM 1846 C C . VAL B 1 50 ? 22.569 28.483 -27.462 1.00 29.64 ? 31 VAL B C 1 ATOM 1847 O O . VAL B 1 50 ? 23.504 27.737 -27.746 1.00 36.84 ? 31 VAL B O 1 ATOM 1848 C CB . VAL B 1 50 ? 21.670 29.381 -29.577 1.00 25.24 ? 31 VAL B CB 1 ATOM 1849 C CG1 . VAL B 1 50 ? 20.362 28.665 -29.336 1.00 24.15 ? 31 VAL B CG1 1 ATOM 1850 C CG2 . VAL B 1 50 ? 21.458 30.618 -30.423 1.00 27.19 ? 31 VAL B CG2 1 ATOM 1851 N N . SER B 1 51 ? 21.741 28.225 -26.467 1.00 28.46 ? 32 SER B N 1 ATOM 1852 C CA . SER B 1 51 ? 21.865 27.001 -25.693 1.00 27.71 ? 32 SER B CA 1 ATOM 1853 C C . SER B 1 51 ? 20.480 26.444 -25.310 1.00 25.03 ? 32 SER B C 1 ATOM 1854 O O . SER B 1 51 ? 19.648 27.173 -24.764 1.00 29.09 ? 32 SER B O 1 ATOM 1855 C CB . SER B 1 51 ? 22.691 27.285 -24.449 1.00 33.10 ? 32 SER B CB 1 ATOM 1856 O OG . SER B 1 51 ? 22.862 26.101 -23.697 1.00 61.67 ? 32 SER B OG 1 ATOM 1857 N N . LEU B 1 52 ? 20.224 25.168 -25.598 1.00 24.94 ? 33 LEU B N 1 ATOM 1858 C CA . LEU B 1 52 ? 18.948 24.549 -25.206 1.00 26.20 ? 33 LEU B CA 1 ATOM 1859 C C . LEU B 1 52 ? 19.079 23.732 -23.915 1.00 27.06 ? 33 LEU B C 1 ATOM 1860 O O . LEU B 1 52 ? 19.965 22.901 -23.783 1.00 31.09 ? 33 LEU B O 1 ATOM 1861 C CB . LEU B 1 52 ? 18.383 23.667 -26.315 1.00 19.92 ? 33 LEU B CB 1 ATOM 1862 C CG . LEU B 1 52 ? 18.337 24.293 -27.712 1.00 20.07 ? 33 LEU B CG 1 ATOM 1863 C CD1 . LEU B 1 52 ? 17.506 23.453 -28.650 1.00 24.68 ? 33 LEU B CD1 1 ATOM 1864 C CD2 . LEU B 1 52 ? 17.794 25.696 -27.665 1.00 24.78 ? 33 LEU B CD2 1 ATOM 1865 N N . LYS B 1 53 ? 18.208 23.990 -22.950 1.00 28.51 ? 34 LYS B N 1 ATOM 1866 C CA . LYS B 1 53 ? 18.158 23.183 -21.742 1.00 25.65 ? 34 LYS B CA 1 ATOM 1867 C C . LYS B 1 53 ? 16.856 22.414 -21.792 1.00 25.62 ? 34 LYS B C 1 ATOM 1868 O O . LYS B 1 53 ? 15.771 23.008 -21.696 1.00 21.98 ? 34 LYS B O 1 ATOM 1869 C CB . LYS B 1 53 ? 18.167 24.056 -20.486 1.00 32.60 ? 34 LYS B CB 1 ATOM 1870 C CG . LYS B 1 53 ? 19.121 25.238 -20.524 1.00 39.35 ? 34 LYS B CG 1 ATOM 1871 C CD . LYS B 1 53 ? 20.568 24.811 -20.376 1.00 47.88 ? 34 LYS B CD 1 ATOM 1872 C CE . LYS B 1 53 ? 21.510 26.018 -20.439 1.00 52.72 ? 34 LYS B CE 1 ATOM 1873 N NZ . LYS B 1 53 ? 22.956 25.598 -20.347 1.00 62.21 ? 34 LYS B NZ 1 ATOM 1874 N N . PHE B 1 54 ? 16.952 21.094 -21.952 1.00 35.03 ? 35 PHE B N 1 ATOM 1875 C CA . PHE B 1 54 ? 15.741 20.271 -22.066 1.00 28.69 ? 35 PHE B CA 1 ATOM 1876 C C . PHE B 1 54 ? 15.026 20.074 -20.739 1.00 26.69 ? 35 PHE B C 1 ATOM 1877 O O . PHE B 1 54 ? 15.644 19.810 -19.700 1.00 22.44 ? 35 PHE B O 1 ATOM 1878 C CB . PHE B 1 54 ? 16.035 18.957 -22.754 1.00 18.59 ? 35 PHE B CB 1 ATOM 1879 C CG . PHE B 1 54 ? 16.511 19.139 -24.146 1.00 22.55 ? 35 PHE B CG 1 ATOM 1880 C CD1 . PHE B 1 54 ? 15.604 19.287 -25.181 1.00 23.56 ? 35 PHE B CD1 1 ATOM 1881 C CD2 . PHE B 1 54 ? 17.865 19.218 -24.422 1.00 25.85 ? 35 PHE B CD2 1 ATOM 1882 C CE1 . PHE B 1 54 ? 16.033 19.469 -26.481 1.00 21.88 ? 35 PHE B CE1 1 ATOM 1883 C CE2 . PHE B 1 54 ? 18.310 19.409 -25.716 1.00 25.91 ? 35 PHE B CE2 1 ATOM 1884 C CZ . PHE B 1 54 ? 17.390 19.537 -26.746 1.00 26.47 ? 35 PHE B CZ 1 ATOM 1885 N N . ILE B 1 55 ? 13.712 20.261 -20.780 1.00 25.42 ? 36 ILE B N 1 ATOM 1886 C CA . ILE B 1 55 ? 12.917 20.181 -19.566 1.00 27.22 ? 36 ILE B CA 1 ATOM 1887 C C . ILE B 1 55 ? 12.012 18.949 -19.587 1.00 24.21 ? 36 ILE B C 1 ATOM 1888 O O . ILE B 1 55 ? 11.834 18.278 -18.561 1.00 22.13 ? 36 ILE B O 1 ATOM 1889 C CB . ILE B 1 55 ? 12.097 21.478 -19.324 1.00 25.27 ? 36 ILE B CB 1 ATOM 1890 C CG1 . ILE B 1 55 ? 12.975 22.724 -19.512 1.00 19.64 ? 36 ILE B CG1 1 ATOM 1891 C CG2 . ILE B 1 55 ? 11.461 21.453 -17.944 1.00 15.88 ? 36 ILE B CG2 1 ATOM 1892 C CD1 . ILE B 1 55 ? 14.138 22.806 -18.551 1.00 19.23 ? 36 ILE B CD1 1 ATOM 1893 N N . ASN B 1 56 ? 11.455 18.646 -20.759 1.00 23.81 ? 37 ASN B N 1 ATOM 1894 C CA . ASN B 1 56 ? 10.534 17.513 -20.888 1.00 20.98 ? 37 ASN B CA 1 ATOM 1895 C C . ASN B 1 56 ? 10.445 16.962 -22.298 1.00 21.22 ? 37 ASN B C 1 ATOM 1896 O O . ASN B 1 56 ? 10.704 17.677 -23.264 1.00 33.29 ? 37 ASN B O 1 ATOM 1897 C CB . ASN B 1 56 ? 9.141 17.923 -20.403 1.00 20.09 ? 37 ASN B CB 1 ATOM 1898 C CG . ASN B 1 56 ? 8.448 16.834 -19.581 1.00 23.20 ? 37 ASN B CG 1 ATOM 1899 O OD1 . ASN B 1 56 ? 8.426 15.667 -19.962 1.00 30.66 ? 37 ASN B OD1 1 ATOM 1900 N ND2 . ASN B 1 56 ? 7.870 17.221 -18.453 1.00 21.14 ? 37 ASN B ND2 1 ATOM 1901 N N . ILE B 1 57 ? 10.094 15.689 -22.411 1.00 20.42 ? 38 ILE B N 1 ATOM 1902 C CA . ILE B 1 57 ? 9.780 15.081 -23.700 1.00 25.26 ? 38 ILE B CA 1 ATOM 1903 C C . ILE B 1 57 ? 8.392 14.466 -23.573 1.00 28.42 ? 38 ILE B C 1 ATOM 1904 O O . ILE B 1 57 ? 8.139 13.688 -22.660 1.00 28.51 ? 38 ILE B O 1 ATOM 1905 C CB . ILE B 1 57 ? 10.856 14.050 -24.131 1.00 25.45 ? 38 ILE B CB 1 ATOM 1906 C CG1 . ILE B 1 57 ? 12.197 14.777 -24.304 1.00 23.95 ? 38 ILE B CG1 1 ATOM 1907 C CG2 . ILE B 1 57 ? 10.446 13.342 -25.423 1.00 21.68 ? 38 ILE B CG2 1 ATOM 1908 C CD1 . ILE B 1 57 ? 13.356 13.922 -24.597 1.00 24.35 ? 38 ILE B CD1 1 ATOM 1909 N N . LEU B 1 58 ? 7.479 14.833 -24.465 1.00 30.73 ? 39 LEU B N 1 ATOM 1910 C CA . LEU B 1 58 ? 6.070 14.670 -24.146 1.00 28.47 ? 39 LEU B CA 1 ATOM 1911 C C . LEU B 1 58 ? 5.324 13.679 -24.982 1.00 33.30 ? 39 LEU B C 1 ATOM 1912 O O . LEU B 1 58 ? 4.592 12.854 -24.443 1.00 34.04 ? 39 LEU B O 1 ATOM 1913 C CB . LEU B 1 58 ? 5.347 16.015 -24.212 1.00 33.01 ? 39 LEU B CB 1 ATOM 1914 C CG . LEU B 1 58 ? 5.680 16.976 -23.081 1.00 30.29 ? 39 LEU B CG 1 ATOM 1915 C CD1 . LEU B 1 58 ? 4.899 18.251 -23.248 1.00 39.18 ? 39 LEU B CD1 1 ATOM 1916 C CD2 . LEU B 1 58 ? 5.378 16.343 -21.735 1.00 32.81 ? 39 LEU B CD2 1 ATOM 1917 N N . GLU B 1 59 ? 5.451 13.788 -26.296 1.00 32.54 ? 40 GLU B N 1 ATOM 1918 C CA . GLU B 1 59 ? 4.639 12.944 -27.160 1.00 38.59 ? 40 GLU B CA 1 ATOM 1919 C C . GLU B 1 59 ? 5.458 12.448 -28.308 1.00 43.38 ? 40 GLU B C 1 ATOM 1920 O O . GLU B 1 59 ? 5.714 13.168 -29.275 1.00 49.36 ? 40 GLU B O 1 ATOM 1921 C CB . GLU B 1 59 ? 3.395 13.673 -27.667 1.00 39.49 ? 40 GLU B CB 1 ATOM 1922 C CG . GLU B 1 59 ? 2.113 13.121 -27.086 1.00 55.58 ? 40 GLU B CG 1 ATOM 1923 C CD . GLU B 1 59 ? 1.057 14.194 -26.895 1.00 78.48 ? 40 GLU B CD 1 ATOM 1924 O OE1 . GLU B 1 59 ? 1.353 15.376 -27.212 1.00 78.27 ? 40 GLU B OE1 1 ATOM 1925 O OE2 . GLU B 1 59 ? -0.057 13.854 -26.426 1.00 78.78 ? 40 GLU B OE2 1 ATOM 1926 N N . VAL B 1 60 ? 5.882 11.205 -28.199 1.00 38.03 ? 41 VAL B N 1 ATOM 1927 C CA . VAL B 1 60 ? 6.724 10.659 -29.232 1.00 35.39 ? 41 VAL B CA 1 ATOM 1928 C C . VAL B 1 60 ? 5.885 9.770 -30.124 1.00 32.19 ? 41 VAL B C 1 ATOM 1929 O O . VAL B 1 60 ? 4.987 9.080 -29.650 1.00 39.21 ? 41 VAL B O 1 ATOM 1930 C CB . VAL B 1 60 ? 7.897 9.927 -28.609 1.00 32.87 ? 41 VAL B CB 1 ATOM 1931 C CG1 . VAL B 1 60 ? 8.656 9.205 -29.646 1.00 30.90 ? 41 VAL B CG1 1 ATOM 1932 C CG2 . VAL B 1 60 ? 8.796 10.937 -27.907 1.00 36.31 ? 41 VAL B CG2 1 ATOM 1933 N N . ASN B 1 61 ? 6.135 9.845 -31.424 1.00 29.30 ? 42 ASN B N 1 ATOM 1934 C CA . ASN B 1 61 ? 5.482 8.972 -32.385 1.00 29.00 ? 42 ASN B CA 1 ATOM 1935 C C . ASN B 1 61 ? 6.542 8.418 -33.343 1.00 37.76 ? 42 ASN B C 1 ATOM 1936 O O . ASN B 1 61 ? 7.051 9.132 -34.215 1.00 33.86 ? 42 ASN B O 1 ATOM 1937 C CB . ASN B 1 61 ? 4.364 9.713 -33.119 1.00 30.56 ? 42 ASN B CB 1 ATOM 1938 C CG . ASN B 1 61 ? 3.520 8.797 -33.998 1.00 37.87 ? 42 ASN B CG 1 ATOM 1939 O OD1 . ASN B 1 61 ? 4.031 7.868 -34.633 1.00 39.67 ? 42 ASN B OD1 1 ATOM 1940 N ND2 . ASN B 1 61 ? 2.208 9.063 -34.041 1.00 40.13 ? 42 ASN B ND2 1 ATOM 1941 N N . GLU B 1 62 ? 6.879 7.141 -33.159 1.00 38.59 ? 43 GLU B N 1 ATOM 1942 C CA . GLU B 1 62 ? 7.923 6.503 -33.954 1.00 37.01 ? 43 GLU B CA 1 ATOM 1943 C C . GLU B 1 62 ? 7.428 6.266 -35.383 1.00 38.92 ? 43 GLU B C 1 ATOM 1944 O O . GLU B 1 62 ? 8.228 6.250 -36.331 1.00 40.62 ? 43 GLU B O 1 ATOM 1945 C CB . GLU B 1 62 ? 8.405 5.197 -33.299 1.00 41.78 ? 43 GLU B CB 1 ATOM 1946 C CG . GLU B 1 62 ? 9.777 4.681 -33.799 1.00 48.62 ? 43 GLU B CG 1 ATOM 1947 C CD . GLU B 1 62 ? 10.254 3.398 -33.078 1.00 55.82 ? 43 GLU B CD 1 ATOM 1948 O OE1 . GLU B 1 62 ? 9.643 3.017 -32.041 1.00 54.37 ? 43 GLU B OE1 1 ATOM 1949 O OE2 . GLU B 1 62 ? 11.241 2.776 -33.555 1.00 45.19 ? 43 GLU B OE2 1 ATOM 1950 N N . ILE B 1 63 ? 6.109 6.113 -35.535 1.00 39.65 ? 44 ILE B N 1 ATOM 1951 C CA . ILE B 1 63 ? 5.506 5.884 -36.854 1.00 41.69 ? 44 ILE B CA 1 ATOM 1952 C C . ILE B 1 63 ? 5.651 7.112 -37.751 1.00 41.20 ? 44 ILE B C 1 ATOM 1953 O O . ILE B 1 63 ? 6.029 6.987 -38.915 1.00 42.33 ? 44 ILE B O 1 ATOM 1954 C CB . ILE B 1 63 ? 3.984 5.520 -36.798 1.00 43.65 ? 44 ILE B CB 1 ATOM 1955 C CG1 . ILE B 1 63 ? 3.704 4.324 -35.880 1.00 33.80 ? 44 ILE B CG1 1 ATOM 1956 C CG2 . ILE B 1 63 ? 3.443 5.282 -38.213 1.00 38.10 ? 44 ILE B CG2 1 ATOM 1957 C CD1 . ILE B 1 63 ? 4.305 3.036 -36.358 1.00 36.60 ? 44 ILE B CD1 1 ATOM 1958 N N . THR B 1 64 ? 5.336 8.289 -37.207 1.00 38.10 ? 45 THR B N 1 ATOM 1959 C CA . THR B 1 64 ? 5.311 9.516 -38.004 1.00 41.03 ? 45 THR B CA 1 ATOM 1960 C C . THR B 1 64 ? 6.578 10.346 -37.853 1.00 39.11 ? 45 THR B C 1 ATOM 1961 O O . THR B 1 64 ? 6.717 11.386 -38.499 1.00 36.39 ? 45 THR B O 1 ATOM 1962 C CB . THR B 1 64 ? 4.131 10.430 -37.625 1.00 44.08 ? 45 THR B CB 1 ATOM 1963 O OG1 . THR B 1 64 ? 4.338 10.962 -36.307 1.00 43.29 ? 45 THR B OG1 1 ATOM 1964 C CG2 . THR B 1 64 ? 2.815 9.679 -37.681 1.00 33.78 ? 45 THR B CG2 1 ATOM 1965 N N . ASN B 1 65 ? 7.480 9.902 -36.983 1.00 37.50 ? 46 ASN B N 1 ATOM 1966 C CA . ASN B 1 65 ? 8.728 10.628 -36.723 1.00 40.42 ? 46 ASN B CA 1 ATOM 1967 C C . ASN B 1 65 ? 8.535 12.077 -36.225 1.00 34.11 ? 46 ASN B C 1 ATOM 1968 O O . ASN B 1 65 ? 9.091 13.021 -36.779 1.00 26.75 ? 46 ASN B O 1 ATOM 1969 C CB . ASN B 1 65 ? 9.654 10.595 -37.945 1.00 35.81 ? 46 ASN B CB 1 ATOM 1970 C CG . ASN B 1 65 ? 10.598 9.409 -37.946 1.00 37.47 ? 46 ASN B CG 1 ATOM 1971 O OD1 . ASN B 1 65 ? 10.882 8.803 -36.908 1.00 40.50 ? 46 ASN B OD1 1 ATOM 1972 N ND2 . ASN B 1 65 ? 11.107 9.082 -39.128 1.00 41.83 ? 46 ASN B ND2 1 ATOM 1973 N N . GLU B 1 66 ? 7.750 12.222 -35.163 1.00 35.90 ? 47 GLU B N 1 ATOM 1974 C CA . GLU B 1 66 ? 7.471 13.512 -34.558 1.00 35.38 ? 47 GLU B CA 1 ATOM 1975 C C . GLU B 1 66 ? 7.637 13.484 -33.041 1.00 34.07 ? 47 GLU B C 1 ATOM 1976 O O . GLU B 1 66 ? 7.218 12.539 -32.392 1.00 37.30 ? 47 GLU B O 1 ATOM 1977 C CB . GLU B 1 66 ? 6.050 13.933 -34.902 1.00 41.33 ? 47 GLU B CB 1 ATOM 1978 C CG . GLU B 1 66 ? 5.828 14.106 -36.392 1.00 48.16 ? 47 GLU B CG 1 ATOM 1979 C CD . GLU B 1 66 ? 4.402 14.514 -36.750 1.00 59.05 ? 47 GLU B CD 1 ATOM 1980 O OE1 . GLU B 1 66 ? 3.631 14.905 -35.835 1.00 68.82 ? 47 GLU B OE1 1 ATOM 1981 O OE2 . GLU B 1 66 ? 4.062 14.440 -37.956 1.00 50.98 ? 47 GLU B OE2 1 ATOM 1982 N N . VAL B 1 67 ? 8.242 14.526 -32.477 1.00 39.89 ? 48 VAL B N 1 ATOM 1983 C CA . VAL B 1 67 ? 8.387 14.625 -31.027 1.00 36.55 ? 48 VAL B CA 1 ATOM 1984 C C . VAL B 1 67 ? 7.869 15.958 -30.518 1.00 34.28 ? 48 VAL B C 1 ATOM 1985 O O . VAL B 1 67 ? 7.825 16.938 -31.252 1.00 32.32 ? 48 VAL B O 1 ATOM 1986 C CB . VAL B 1 67 ? 9.850 14.455 -30.562 1.00 29.05 ? 48 VAL B CB 1 ATOM 1987 C CG1 . VAL B 1 67 ? 10.404 13.160 -31.047 1.00 38.80 ? 48 VAL B CG1 1 ATOM 1988 C CG2 . VAL B 1 67 ? 10.689 15.573 -31.092 1.00 34.27 ? 48 VAL B CG2 1 ATOM 1989 N N . ASP B 1 68 ? 7.493 15.974 -29.244 1.00 40.22 ? 49 ASP B N 1 ATOM 1990 C CA . ASP B 1 68 ? 7.035 17.176 -28.564 1.00 30.67 ? 49 ASP B CA 1 ATOM 1991 C C . ASP B 1 68 ? 8.009 17.517 -27.451 1.00 33.48 ? 49 ASP B C 1 ATOM 1992 O O . ASP B 1 68 ? 8.124 16.784 -26.465 1.00 35.01 ? 49 ASP B O 1 ATOM 1993 C CB . ASP B 1 68 ? 5.680 16.915 -27.942 1.00 37.94 ? 49 ASP B CB 1 ATOM 1994 C CG . ASP B 1 68 ? 4.676 17.962 -28.307 1.00 46.31 ? 49 ASP B CG 1 ATOM 1995 O OD1 . ASP B 1 68 ? 4.875 18.583 -29.369 1.00 52.63 ? 49 ASP B OD1 1 ATOM 1996 O OD2 . ASP B 1 68 ? 3.698 18.164 -27.546 1.00 57.64 ? 49 ASP B OD2 1 ATOM 1997 N N . VAL B 1 69 ? 8.718 18.626 -27.594 1.00 26.97 ? 50 VAL B N 1 ATOM 1998 C CA . VAL B 1 69 ? 9.726 18.963 -26.610 1.00 24.60 ? 50 VAL B CA 1 ATOM 1999 C C . VAL B 1 69 ? 9.413 20.254 -25.838 1.00 29.76 ? 50 VAL B C 1 ATOM 2000 O O . VAL B 1 69 ? 8.837 21.200 -26.386 1.00 24.74 ? 50 VAL B O 1 ATOM 2001 C CB . VAL B 1 69 ? 11.079 19.054 -27.278 1.00 28.32 ? 50 VAL B CB 1 ATOM 2002 C CG1 . VAL B 1 69 ? 12.173 19.262 -26.234 1.00 30.68 ? 50 VAL B CG1 1 ATOM 2003 C CG2 . VAL B 1 69 ? 11.331 17.779 -28.056 1.00 33.31 ? 50 VAL B CG2 1 ATOM 2004 N N . VAL B 1 70 ? 9.765 20.269 -24.552 1.00 23.94 ? 51 VAL B N 1 ATOM 2005 C CA . VAL B 1 70 ? 9.782 21.498 -23.775 1.00 17.74 ? 51 VAL B CA 1 ATOM 2006 C C . VAL B 1 70 ? 11.225 21.774 -23.397 1.00 22.77 ? 51 VAL B C 1 ATOM 2007 O O . VAL B 1 70 ? 11.904 20.905 -22.826 1.00 24.80 ? 51 VAL B O 1 ATOM 2008 C CB . VAL B 1 70 ? 8.934 21.387 -22.507 1.00 18.23 ? 51 VAL B CB 1 ATOM 2009 C CG1 . VAL B 1 70 ? 9.180 22.583 -21.598 1.00 14.01 ? 51 VAL B CG1 1 ATOM 2010 C CG2 . VAL B 1 70 ? 7.468 21.274 -22.880 1.00 22.19 ? 51 VAL B CG2 1 ATOM 2011 N N . PHE B 1 71 ? 11.696 22.979 -23.723 1.00 22.23 ? 52 PHE B N 1 ATOM 2012 C CA . PHE B 1 71 ? 13.078 23.371 -23.454 1.00 21.64 ? 52 PHE B CA 1 ATOM 2013 C C . PHE B 1 71 ? 13.203 24.870 -23.173 1.00 23.96 ? 52 PHE B C 1 ATOM 2014 O O . PHE B 1 71 ? 12.361 25.661 -23.617 1.00 23.27 ? 52 PHE B O 1 ATOM 2015 C CB . PHE B 1 71 ? 13.949 22.999 -24.655 1.00 20.67 ? 52 PHE B CB 1 ATOM 2016 C CG . PHE B 1 71 ? 13.499 23.626 -25.938 1.00 22.29 ? 52 PHE B CG 1 ATOM 2017 C CD1 . PHE B 1 71 ? 12.472 23.059 -26.676 1.00 23.40 ? 52 PHE B CD1 1 ATOM 2018 C CD2 . PHE B 1 71 ? 14.102 24.789 -26.409 1.00 21.80 ? 52 PHE B CD2 1 ATOM 2019 C CE1 . PHE B 1 71 ? 12.038 23.647 -27.865 1.00 23.62 ? 52 PHE B CE1 1 ATOM 2020 C CE2 . PHE B 1 71 ? 13.674 25.379 -27.592 1.00 22.00 ? 52 PHE B CE2 1 ATOM 2021 C CZ . PHE B 1 71 ? 12.633 24.806 -28.319 1.00 18.83 ? 52 PHE B CZ 1 ATOM 2022 N N . TRP B 1 72 ? 14.252 25.258 -22.442 1.00 22.67 ? 53 TRP B N 1 ATOM 2023 C CA . TRP B 1 72 ? 14.627 26.668 -22.321 1.00 19.04 ? 53 TRP B CA 1 ATOM 2024 C C . TRP B 1 72 ? 15.554 26.991 -23.475 1.00 21.94 ? 53 TRP B C 1 ATOM 2025 O O . TRP B 1 72 ? 16.513 26.256 -23.709 1.00 17.57 ? 53 TRP B O 1 ATOM 2026 C CB . TRP B 1 72 ? 15.382 26.953 -21.024 1.00 15.24 ? 53 TRP B CB 1 ATOM 2027 C CG . TRP B 1 72 ? 14.607 26.704 -19.795 1.00 16.05 ? 53 TRP B CG 1 ATOM 2028 C CD1 . TRP B 1 72 ? 13.315 26.262 -19.706 1.00 19.66 ? 53 TRP B CD1 1 ATOM 2029 C CD2 . TRP B 1 72 ? 15.074 26.862 -18.453 1.00 20.26 ? 53 TRP B CD2 1 ATOM 2030 N NE1 . TRP B 1 72 ? 12.948 26.140 -18.385 1.00 18.05 ? 53 TRP B NE1 1 ATOM 2031 C CE2 . TRP B 1 72 ? 14.004 26.498 -17.596 1.00 20.63 ? 53 TRP B CE2 1 ATOM 2032 C CE3 . TRP B 1 72 ? 16.281 27.288 -17.890 1.00 26.83 ? 53 TRP B CE3 1 ATOM 2033 C CZ2 . TRP B 1 72 ? 14.117 26.546 -16.202 1.00 19.76 ? 53 TRP B CZ2 1 ATOM 2034 C CZ3 . TRP B 1 72 ? 16.395 27.338 -16.503 1.00 28.45 ? 53 TRP B CZ3 1 ATOM 2035 C CH2 . TRP B 1 72 ? 15.315 26.965 -15.674 1.00 26.01 ? 53 TRP B CH2 1 ATOM 2036 N N . GLN B 1 73 ? 15.273 28.087 -24.188 1.00 24.96 ? 54 GLN B N 1 ATOM 2037 C CA . GLN B 1 73 ? 16.120 28.529 -25.295 1.00 21.33 ? 54 GLN B CA 1 ATOM 2038 C C . GLN B 1 73 ? 16.964 29.724 -24.877 1.00 20.54 ? 54 GLN B C 1 ATOM 2039 O O . GLN B 1 73 ? 16.627 30.869 -25.144 1.00 24.15 ? 54 GLN B O 1 ATOM 2040 C CB . GLN B 1 73 ? 15.277 28.866 -26.514 1.00 15.68 ? 54 GLN B CB 1 ATOM 2041 C CG . GLN B 1 73 ? 16.096 29.269 -27.711 1.00 18.00 ? 54 GLN B CG 1 ATOM 2042 C CD . GLN B 1 73 ? 15.252 29.446 -28.963 1.00 34.32 ? 54 GLN B CD 1 ATOM 2043 O OE1 . GLN B 1 73 ? 14.511 28.534 -29.386 1.00 27.25 ? 54 GLN B OE1 1 ATOM 2044 N NE2 . GLN B 1 73 ? 15.341 30.638 -29.558 1.00 45.44 ? 54 GLN B NE2 1 ATOM 2045 N N . GLN B 1 74 ? 18.073 29.455 -24.210 1.00 21.66 ? 55 GLN B N 1 ATOM 2046 C CA . GLN B 1 74 ? 18.896 30.537 -23.685 1.00 25.12 ? 55 GLN B CA 1 ATOM 2047 C C . GLN B 1 74 ? 19.684 31.257 -24.783 1.00 27.11 ? 55 GLN B C 1 ATOM 2048 O O . GLN B 1 74 ? 20.586 30.678 -25.398 1.00 26.13 ? 55 GLN B O 1 ATOM 2049 C CB . GLN B 1 74 ? 19.849 30.008 -22.627 1.00 27.95 ? 55 GLN B CB 1 ATOM 2050 C CG . GLN B 1 74 ? 20.777 31.062 -22.072 1.00 30.87 ? 55 GLN B CG 1 ATOM 2051 C CD . GLN B 1 74 ? 21.689 30.501 -21.005 1.00 46.06 ? 55 GLN B CD 1 ATOM 2052 O OE1 . GLN B 1 74 ? 21.280 29.647 -20.205 1.00 51.27 ? 55 GLN B OE1 1 ATOM 2053 N NE2 . GLN B 1 74 ? 22.940 30.966 -20.991 1.00 48.44 ? 55 GLN B NE2 1 ATOM 2054 N N . THR B 1 75 ? 19.347 32.527 -25.006 1.00 25.34 ? 56 THR B N 1 ATOM 2055 C CA . THR B 1 75 ? 19.904 33.316 -26.104 1.00 18.07 ? 56 THR B CA 1 ATOM 2056 C C . THR B 1 75 ? 20.629 34.553 -25.571 1.00 24.94 ? 56 THR B C 1 ATOM 2057 O O . THR B 1 75 ? 20.096 35.293 -24.734 1.00 23.42 ? 56 THR B O 1 ATOM 2058 C CB . THR B 1 75 ? 18.797 33.747 -27.062 1.00 21.72 ? 56 THR B CB 1 ATOM 2059 O OG1 . THR B 1 75 ? 17.944 32.620 -27.363 1.00 23.85 ? 56 THR B OG1 1 ATOM 2060 C CG2 . THR B 1 75 ? 19.389 34.297 -28.333 1.00 21.67 ? 56 THR B CG2 1 ATOM 2061 N N . THR B 1 76 ? 21.848 34.779 -26.056 1.00 24.84 ? 57 THR B N 1 ATOM 2062 C CA . THR B 1 76 ? 22.704 35.833 -25.503 1.00 25.95 ? 57 THR B CA 1 ATOM 2063 C C . THR B 1 76 ? 23.446 36.661 -26.573 1.00 25.33 ? 57 THR B C 1 ATOM 2064 O O . THR B 1 76 ? 24.045 36.115 -27.492 1.00 27.81 ? 57 THR B O 1 ATOM 2065 C CB . THR B 1 76 ? 23.706 35.234 -24.482 1.00 22.21 ? 57 THR B CB 1 ATOM 2066 O OG1 . THR B 1 76 ? 22.979 34.783 -23.326 1.00 24.23 ? 57 THR B OG1 1 ATOM 2067 C CG2 . THR B 1 76 ? 24.740 36.285 -24.046 1.00 30.52 ? 57 THR B CG2 1 ATOM 2068 N N . TRP B 1 77 ? 23.416 37.981 -26.453 1.00 24.65 ? 58 TRP B N 1 ATOM 2069 C CA . TRP B 1 77 ? 24.126 38.811 -27.416 1.00 25.96 ? 58 TRP B CA 1 ATOM 2070 C C . TRP B 1 77 ? 24.442 40.165 -26.814 1.00 30.34 ? 58 TRP B C 1 ATOM 2071 O O . TRP B 1 77 ? 24.039 40.465 -25.689 1.00 32.96 ? 58 TRP B O 1 ATOM 2072 C CB . TRP B 1 77 ? 23.299 39.001 -28.689 1.00 24.49 ? 58 TRP B CB 1 ATOM 2073 C CG . TRP B 1 77 ? 22.079 39.853 -28.460 1.00 30.76 ? 58 TRP B CG 1 ATOM 2074 C CD1 . TRP B 1 77 ? 21.965 41.227 -28.626 1.00 25.82 ? 58 TRP B CD1 1 ATOM 2075 C CD2 . TRP B 1 77 ? 20.804 39.397 -27.997 1.00 25.66 ? 58 TRP B CD2 1 ATOM 2076 N NE1 . TRP B 1 77 ? 20.693 41.632 -28.290 1.00 20.90 ? 58 TRP B NE1 1 ATOM 2077 C CE2 . TRP B 1 77 ? 19.962 40.533 -27.909 1.00 24.16 ? 58 TRP B CE2 1 ATOM 2078 C CE3 . TRP B 1 77 ? 20.298 38.143 -27.646 1.00 21.27 ? 58 TRP B CE3 1 ATOM 2079 C CZ2 . TRP B 1 77 ? 18.637 40.436 -27.495 1.00 20.70 ? 58 TRP B CZ2 1 ATOM 2080 C CZ3 . TRP B 1 77 ? 18.992 38.053 -27.227 1.00 22.43 ? 58 TRP B CZ3 1 ATOM 2081 C CH2 . TRP B 1 77 ? 18.170 39.197 -27.154 1.00 20.89 ? 58 TRP B CH2 1 ATOM 2082 N N . SER B 1 78 ? 25.140 40.997 -27.576 1.00 27.53 ? 59 SER B N 1 ATOM 2083 C CA . SER B 1 78 ? 25.540 42.301 -27.071 1.00 26.45 ? 59 SER B CA 1 ATOM 2084 C C . SER B 1 78 ? 24.936 43.461 -27.858 1.00 26.01 ? 59 SER B C 1 ATOM 2085 O O . SER B 1 78 ? 24.942 43.452 -29.092 1.00 29.55 ? 59 SER B O 1 ATOM 2086 C CB . SER B 1 78 ? 27.060 42.401 -27.061 1.00 38.43 ? 59 SER B CB 1 ATOM 2087 O OG . SER B 1 78 ? 27.474 43.675 -26.605 1.00 51.78 ? 59 SER B OG 1 ATOM 2088 N N . ASP B 1 79 ? 24.422 44.458 -27.132 1.00 29.28 ? 60 ASP B N 1 ATOM 2089 C CA . ASP B 1 79 ? 23.822 45.662 -27.733 1.00 33.20 ? 60 ASP B CA 1 ATOM 2090 C C . ASP B 1 79 ? 24.271 46.926 -26.990 1.00 30.17 ? 60 ASP B C 1 ATOM 2091 O O . ASP B 1 79 ? 23.659 47.305 -25.991 1.00 32.59 ? 60 ASP B O 1 ATOM 2092 C CB . ASP B 1 79 ? 22.283 45.554 -27.727 1.00 33.41 ? 60 ASP B CB 1 ATOM 2093 C CG . ASP B 1 79 ? 21.601 46.581 -28.648 1.00 41.24 ? 60 ASP B CG 1 ATOM 2094 O OD1 . ASP B 1 79 ? 22.213 47.643 -28.941 1.00 44.57 ? 60 ASP B OD1 1 ATOM 2095 O OD2 . ASP B 1 79 ? 20.446 46.320 -29.070 1.00 33.12 ? 60 ASP B OD2 1 ATOM 2096 N N . ARG B 1 80 ? 25.315 47.586 -27.492 1.00 27.13 ? 61 ARG B N 1 ATOM 2097 C CA . ARG B 1 80 ? 25.915 48.734 -26.790 1.00 33.07 ? 61 ARG B CA 1 ATOM 2098 C C . ARG B 1 80 ? 24.982 49.944 -26.673 1.00 29.39 ? 61 ARG B C 1 ATOM 2099 O O . ARG B 1 80 ? 25.154 50.777 -25.800 1.00 26.75 ? 61 ARG B O 1 ATOM 2100 C CB . ARG B 1 80 ? 27.232 49.156 -27.446 1.00 40.99 ? 61 ARG B CB 1 ATOM 2101 C CG . ARG B 1 80 ? 28.212 48.008 -27.714 1.00 62.41 ? 61 ARG B CG 1 ATOM 2102 C CD . ARG B 1 80 ? 29.002 47.565 -26.471 1.00 65.52 ? 61 ARG B CD 1 ATOM 2103 N NE . ARG B 1 80 ? 30.082 46.632 -26.825 1.00 80.94 ? 61 ARG B NE 1 ATOM 2104 C CZ . ARG B 1 80 ? 30.263 45.419 -26.293 1.00 83.09 ? 61 ARG B CZ 1 ATOM 2105 N NH1 . ARG B 1 80 ? 29.437 44.963 -25.348 1.00 64.80 ? 61 ARG B NH1 1 ATOM 2106 N NH2 . ARG B 1 80 ? 31.283 44.664 -26.705 1.00 73.87 ? 61 ARG B NH2 1 ATOM 2107 N N . THR B 1 81 ? 24.009 50.032 -27.572 1.00 30.71 ? 62 THR B N 1 ATOM 2108 C CA . THR B 1 81 ? 22.942 51.025 -27.513 1.00 26.23 ? 62 THR B CA 1 ATOM 2109 C C . THR B 1 81 ? 22.229 51.057 -26.151 1.00 27.48 ? 62 THR B C 1 ATOM 2110 O O . THR B 1 81 ? 21.704 52.083 -25.743 1.00 26.30 ? 62 THR B O 1 ATOM 2111 C CB . THR B 1 81 ? 21.889 50.704 -28.613 1.00 32.24 ? 62 THR B CB 1 ATOM 2112 O OG1 . THR B 1 81 ? 22.531 50.674 -29.892 1.00 34.14 ? 62 THR B OG1 1 ATOM 2113 C CG2 . THR B 1 81 ? 20.733 51.704 -28.643 1.00 38.68 ? 62 THR B CG2 1 ATOM 2114 N N . LEU B 1 82 ? 22.192 49.927 -25.457 1.00 28.07 ? 63 LEU B N 1 ATOM 2115 C CA . LEU B 1 82 ? 21.460 49.842 -24.195 1.00 25.11 ? 63 LEU B CA 1 ATOM 2116 C C . LEU B 1 82 ? 22.307 50.170 -22.960 1.00 26.42 ? 63 LEU B C 1 ATOM 2117 O O . LEU B 1 82 ? 21.783 50.211 -21.843 1.00 24.25 ? 63 LEU B O 1 ATOM 2118 C CB . LEU B 1 82 ? 20.876 48.443 -24.020 1.00 21.19 ? 63 LEU B CB 1 ATOM 2119 C CG . LEU B 1 82 ? 20.057 47.908 -25.179 1.00 21.98 ? 63 LEU B CG 1 ATOM 2120 C CD1 . LEU B 1 82 ? 19.860 46.406 -25.036 1.00 25.34 ? 63 LEU B CD1 1 ATOM 2121 C CD2 . LEU B 1 82 ? 18.735 48.620 -25.189 1.00 22.63 ? 63 LEU B CD2 1 ATOM 2122 N N . ALA B 1 83 ? 23.607 50.389 -23.150 1.00 28.87 ? 64 ALA B N 1 ATOM 2123 C CA . ALA B 1 83 ? 24.533 50.524 -22.018 1.00 22.82 ? 64 ALA B CA 1 ATOM 2124 C C . ALA B 1 83 ? 24.321 51.820 -21.226 1.00 26.51 ? 64 ALA B C 1 ATOM 2125 O O . ALA B 1 83 ? 23.832 52.823 -21.753 1.00 24.26 ? 64 ALA B O 1 ATOM 2126 C CB . ALA B 1 83 ? 25.979 50.413 -22.483 1.00 18.83 ? 64 ALA B CB 1 ATOM 2127 N N . TRP B 1 84 ? 24.694 51.792 -19.953 1.00 26.22 ? 65 TRP B N 1 ATOM 2128 C CA . TRP B 1 84 ? 24.645 52.982 -19.119 1.00 23.48 ? 65 TRP B CA 1 ATOM 2129 C C . TRP B 1 84 ? 25.799 52.954 -18.109 1.00 28.13 ? 65 TRP B C 1 ATOM 2130 O O . TRP B 1 84 ? 26.423 51.911 -17.915 1.00 25.25 ? 65 TRP B O 1 ATOM 2131 C CB . TRP B 1 84 ? 23.288 53.093 -18.414 1.00 20.17 ? 65 TRP B CB 1 ATOM 2132 C CG . TRP B 1 84 ? 23.010 52.036 -17.358 1.00 24.73 ? 65 TRP B CG 1 ATOM 2133 C CD1 . TRP B 1 84 ? 23.288 52.117 -16.020 1.00 26.82 ? 65 TRP B CD1 1 ATOM 2134 C CD2 . TRP B 1 84 ? 22.379 50.751 -17.557 1.00 25.92 ? 65 TRP B CD2 1 ATOM 2135 N NE1 . TRP B 1 84 ? 22.881 50.963 -15.381 1.00 25.77 ? 65 TRP B NE1 1 ATOM 2136 C CE2 . TRP B 1 84 ? 22.309 50.117 -16.299 1.00 25.92 ? 65 TRP B CE2 1 ATOM 2137 C CE3 . TRP B 1 84 ? 21.877 50.074 -18.680 1.00 24.31 ? 65 TRP B CE3 1 ATOM 2138 C CZ2 . TRP B 1 84 ? 21.746 48.835 -16.133 1.00 26.61 ? 65 TRP B CZ2 1 ATOM 2139 C CZ3 . TRP B 1 84 ? 21.322 48.808 -18.514 1.00 21.21 ? 65 TRP B CZ3 1 ATOM 2140 C CH2 . TRP B 1 84 ? 21.261 48.202 -17.250 1.00 22.79 ? 65 TRP B CH2 1 ATOM 2141 N N . ASN B 1 85 ? 26.090 54.100 -17.487 1.00 34.72 ? 66 ASN B N 1 ATOM 2142 C CA . ASN B 1 85 ? 27.113 54.190 -16.431 1.00 36.26 ? 66 ASN B CA 1 ATOM 2143 C C . ASN B 1 85 ? 26.550 53.619 -15.122 1.00 38.01 ? 66 ASN B C 1 ATOM 2144 O O . ASN B 1 85 ? 25.629 54.205 -14.537 1.00 39.30 ? 66 ASN B O 1 ATOM 2145 C CB . ASN B 1 85 ? 27.552 55.663 -16.246 1.00 39.42 ? 66 ASN B CB 1 ATOM 2146 C CG . ASN B 1 85 ? 28.786 55.828 -15.334 1.00 50.10 ? 66 ASN B CG 1 ATOM 2147 O OD1 . ASN B 1 85 ? 29.120 54.939 -14.540 1.00 55.96 ? 66 ASN B OD1 1 ATOM 2148 N ND2 . ASN B 1 85 ? 29.455 56.988 -15.440 1.00 43.68 ? 66 ASN B ND2 1 ATOM 2149 N N . SER B 1 86 ? 27.085 52.486 -14.658 1.00 29.37 ? 67 SER B N 1 ATOM 2150 C CA . SER B 1 86 ? 26.511 51.843 -13.468 1.00 40.61 ? 67 SER B CA 1 ATOM 2151 C C . SER B 1 86 ? 27.213 52.226 -12.171 1.00 48.60 ? 67 SER B C 1 ATOM 2152 O O . SER B 1 86 ? 27.194 51.456 -11.207 1.00 47.10 ? 67 SER B O 1 ATOM 2153 C CB . SER B 1 86 ? 26.485 50.319 -13.611 1.00 39.61 ? 67 SER B CB 1 ATOM 2154 O OG . SER B 1 86 ? 27.776 49.761 -13.453 1.00 31.43 ? 67 SER B OG 1 ATOM 2155 N N . SER B 1 87 ? 27.811 53.419 -12.156 1.00 57.14 ? 68 SER B N 1 ATOM 2156 C CA . SER B 1 87 ? 28.620 53.887 -11.030 1.00 56.55 ? 68 SER B CA 1 ATOM 2157 C C . SER B 1 87 ? 27.874 53.828 -9.685 1.00 61.10 ? 68 SER B C 1 ATOM 2158 O O . SER B 1 87 ? 28.254 53.064 -8.783 1.00 70.68 ? 68 SER B O 1 ATOM 2159 C CB . SER B 1 87 ? 29.154 55.298 -11.306 1.00 58.70 ? 68 SER B CB 1 ATOM 2160 O OG . SER B 1 87 ? 30.119 55.677 -10.336 1.00 57.22 ? 68 SER B OG 1 ATOM 2161 N N . HIS B 1 88 ? 26.817 54.621 -9.549 1.00 48.65 ? 69 HIS B N 1 ATOM 2162 C CA . HIS B 1 88 ? 26.000 54.559 -8.341 1.00 48.70 ? 69 HIS B CA 1 ATOM 2163 C C . HIS B 1 88 ? 24.588 54.176 -8.732 1.00 46.56 ? 69 HIS B C 1 ATOM 2164 O O . HIS B 1 88 ? 23.618 54.808 -8.326 1.00 51.70 ? 69 HIS B O 1 ATOM 2165 C CB . HIS B 1 88 ? 26.020 55.892 -7.590 1.00 56.15 ? 69 HIS B CB 1 ATOM 2166 C CG . HIS B 1 88 ? 27.377 56.275 -7.098 1.00 71.68 ? 69 HIS B CG 1 ATOM 2167 N ND1 . HIS B 1 88 ? 27.978 55.661 -6.021 1.00 91.77 ? 69 HIS B ND1 1 ATOM 2168 C CD2 . HIS B 1 88 ? 28.266 57.194 -7.553 1.00 71.66 ? 69 HIS B CD2 1 ATOM 2169 C CE1 . HIS B 1 88 ? 29.174 56.190 -5.826 1.00 92.07 ? 69 HIS B CE1 1 ATOM 2170 N NE2 . HIS B 1 88 ? 29.370 57.124 -6.742 1.00 79.82 ? 69 HIS B NE2 1 ATOM 2171 N N . SER B 1 89 ? 24.488 53.119 -9.525 1.00 44.67 ? 70 SER B N 1 ATOM 2172 C CA . SER B 1 89 ? 23.252 52.780 -10.196 1.00 38.71 ? 70 SER B CA 1 ATOM 2173 C C . SER B 1 89 ? 23.098 51.281 -10.222 1.00 32.18 ? 70 SER B C 1 ATOM 2174 O O . SER B 1 89 ? 24.069 50.561 -9.995 1.00 26.73 ? 70 SER B O 1 ATOM 2175 C CB . SER B 1 89 ? 23.301 53.309 -11.629 1.00 41.05 ? 70 SER B CB 1 ATOM 2176 O OG . SER B 1 89 ? 23.629 54.685 -11.640 1.00 48.34 ? 70 SER B OG 1 ATOM 2177 N N . PRO B 1 90 ? 21.871 50.805 -10.505 1.00 37.32 ? 71 PRO B N 1 ATOM 2178 C CA . PRO B 1 90 ? 21.680 49.367 -10.735 1.00 33.00 ? 71 PRO B CA 1 ATOM 2179 C C . PRO B 1 90 ? 22.535 48.910 -11.914 1.00 31.85 ? 71 PRO B C 1 ATOM 2180 O O . PRO B 1 90 ? 22.735 49.682 -12.858 1.00 34.74 ? 71 PRO B O 1 ATOM 2181 C CB . PRO B 1 90 ? 20.194 49.264 -11.102 1.00 34.61 ? 71 PRO B CB 1 ATOM 2182 C CG . PRO B 1 90 ? 19.546 50.496 -10.525 1.00 36.64 ? 71 PRO B CG 1 ATOM 2183 C CD . PRO B 1 90 ? 20.602 51.565 -10.575 1.00 34.72 ? 71 PRO B CD 1 ATOM 2184 N N . ASP B 1 91 ? 23.033 47.680 -11.859 1.00 27.22 ? 72 ASP B N 1 ATOM 2185 C CA . ASP B 1 91 ? 23.837 47.133 -12.944 1.00 32.52 ? 72 ASP B CA 1 ATOM 2186 C C . ASP B 1 91 ? 23.033 46.167 -13.833 1.00 33.66 ? 72 ASP B C 1 ATOM 2187 O O . ASP B 1 91 ? 23.585 45.559 -14.762 1.00 29.90 ? 72 ASP B O 1 ATOM 2188 C CB . ASP B 1 91 ? 25.056 46.421 -12.366 1.00 40.20 ? 72 ASP B CB 1 ATOM 2189 C CG . ASP B 1 91 ? 24.692 45.536 -11.180 1.00 53.94 ? 72 ASP B CG 1 ATOM 2190 O OD1 . ASP B 1 91 ? 23.499 45.570 -10.768 1.00 46.04 ? 72 ASP B OD1 1 ATOM 2191 O OD2 . ASP B 1 91 ? 25.589 44.820 -10.657 1.00 60.54 ? 72 ASP B OD2 1 ATOM 2192 N N . GLN B 1 92 ? 21.734 46.040 -13.553 1.00 30.28 ? 73 GLN B N 1 ATOM 2193 C CA . GLN B 1 92 ? 20.848 45.219 -14.366 1.00 28.53 ? 73 GLN B CA 1 ATOM 2194 C C . GLN B 1 92 ? 19.374 45.630 -14.260 1.00 26.50 ? 73 GLN B C 1 ATOM 2195 O O . GLN B 1 92 ? 18.938 46.118 -13.220 1.00 31.74 ? 73 GLN B O 1 ATOM 2196 C CB . GLN B 1 92 ? 20.969 43.785 -13.910 1.00 35.28 ? 73 GLN B CB 1 ATOM 2197 C CG . GLN B 1 92 ? 20.674 43.669 -12.444 1.00 44.22 ? 73 GLN B CG 1 ATOM 2198 C CD . GLN B 1 92 ? 20.514 42.242 -12.016 1.00 50.81 ? 73 GLN B CD 1 ATOM 2199 O OE1 . GLN B 1 92 ? 21.262 41.367 -12.457 1.00 50.60 ? 73 GLN B OE1 1 ATOM 2200 N NE2 . GLN B 1 92 ? 19.526 41.986 -11.157 1.00 55.42 ? 73 GLN B NE2 1 ATOM 2201 N N . VAL B 1 93 ? 18.615 45.415 -15.338 1.00 24.63 ? 74 VAL B N 1 ATOM 2202 C CA . VAL B 1 93 ? 17.163 45.622 -15.350 1.00 23.31 ? 74 VAL B CA 1 ATOM 2203 C C . VAL B 1 93 ? 16.464 44.542 -16.206 1.00 24.27 ? 74 VAL B C 1 ATOM 2204 O O . VAL B 1 93 ? 17.109 43.869 -17.012 1.00 23.92 ? 74 VAL B O 1 ATOM 2205 C CB . VAL B 1 93 ? 16.785 47.017 -15.882 1.00 21.58 ? 74 VAL B CB 1 ATOM 2206 C CG1 . VAL B 1 93 ? 17.220 48.118 -14.920 1.00 22.78 ? 74 VAL B CG1 1 ATOM 2207 C CG2 . VAL B 1 93 ? 17.395 47.231 -17.257 1.00 25.67 ? 74 VAL B CG2 1 ATOM 2208 N N . SER B 1 94 ? 15.159 44.362 -16.017 1.00 19.73 ? 75 SER B N 1 ATOM 2209 C CA . SER B 1 94 ? 14.398 43.453 -16.863 1.00 19.80 ? 75 SER B CA 1 ATOM 2210 C C . SER B 1 94 ? 13.584 44.283 -17.834 1.00 22.55 ? 75 SER B C 1 ATOM 2211 O O . SER B 1 94 ? 12.932 45.263 -17.434 1.00 17.65 ? 75 SER B O 1 ATOM 2212 C CB . SER B 1 94 ? 13.466 42.567 -16.034 1.00 21.89 ? 75 SER B CB 1 ATOM 2213 O OG . SER B 1 94 ? 14.181 41.491 -15.463 1.00 33.17 ? 75 SER B OG 1 ATOM 2214 N N . VAL B 1 95 ? 13.623 43.901 -19.111 1.00 19.50 ? 76 VAL B N 1 ATOM 2215 C CA . VAL B 1 95 ? 13.022 44.731 -20.156 1.00 17.37 ? 76 VAL B CA 1 ATOM 2216 C C . VAL B 1 95 ? 12.094 43.900 -20.998 1.00 16.98 ? 76 VAL B C 1 ATOM 2217 O O . VAL B 1 95 ? 12.468 42.810 -21.423 1.00 21.34 ? 76 VAL B O 1 ATOM 2218 C CB . VAL B 1 95 ? 14.105 45.333 -21.074 1.00 18.09 ? 76 VAL B CB 1 ATOM 2219 C CG1 . VAL B 1 95 ? 13.467 46.177 -22.144 1.00 19.29 ? 76 VAL B CG1 1 ATOM 2220 C CG2 . VAL B 1 95 ? 15.102 46.157 -20.280 1.00 17.78 ? 76 VAL B CG2 1 ATOM 2221 N N . PRO B 1 96 ? 10.877 44.401 -21.245 1.00 16.86 ? 77 PRO B N 1 ATOM 2222 C CA . PRO B 1 96 ? 9.984 43.665 -22.157 1.00 17.31 ? 77 PRO B CA 1 ATOM 2223 C C . PRO B 1 96 ? 10.644 43.547 -23.542 1.00 16.56 ? 77 PRO B C 1 ATOM 2224 O O . PRO B 1 96 ? 11.203 44.547 -24.021 1.00 17.49 ? 77 PRO B O 1 ATOM 2225 C CB . PRO B 1 96 ? 8.743 44.572 -22.229 1.00 16.15 ? 77 PRO B CB 1 ATOM 2226 C CG . PRO B 1 96 ? 8.809 45.427 -20.988 1.00 15.04 ? 77 PRO B CG 1 ATOM 2227 C CD . PRO B 1 96 ? 10.272 45.646 -20.734 1.00 14.12 ? 77 PRO B CD 1 ATOM 2228 N N . ILE B 1 97 ? 10.592 42.372 -24.170 1.00 11.86 ? 78 ILE B N 1 ATOM 2229 C CA . ILE B 1 97 ? 11.313 42.179 -25.430 1.00 12.56 ? 78 ILE B CA 1 ATOM 2230 C C . ILE B 1 97 ? 10.763 43.033 -26.561 1.00 12.90 ? 78 ILE B C 1 ATOM 2231 O O . ILE B 1 97 ? 11.440 43.259 -27.547 1.00 16.96 ? 78 ILE B O 1 ATOM 2232 C CB . ILE B 1 97 ? 11.382 40.708 -25.899 1.00 13.94 ? 78 ILE B CB 1 ATOM 2233 C CG1 . ILE B 1 97 ? 9.986 40.157 -26.166 1.00 14.07 ? 78 ILE B CG1 1 ATOM 2234 C CG2 . ILE B 1 97 ? 12.155 39.855 -24.883 1.00 11.94 ? 78 ILE B CG2 1 ATOM 2235 C CD1 . ILE B 1 97 ? 9.995 38.819 -26.842 1.00 11.78 ? 78 ILE B CD1 1 ATOM 2236 N N . SER B 1 98 ? 9.534 43.507 -26.422 1.00 14.11 ? 79 SER B N 1 ATOM 2237 C CA . SER B 1 98 ? 8.969 44.430 -27.402 1.00 13.89 ? 79 SER B CA 1 ATOM 2238 C C . SER B 1 98 ? 9.771 45.756 -27.493 1.00 18.36 ? 79 SER B C 1 ATOM 2239 O O . SER B 1 98 ? 9.677 46.479 -28.485 1.00 18.42 ? 79 SER B O 1 ATOM 2240 C CB . SER B 1 98 ? 7.488 44.697 -27.099 1.00 14.73 ? 79 SER B CB 1 ATOM 2241 O OG . SER B 1 98 ? 7.331 45.488 -25.924 1.00 20.07 ? 79 SER B OG 1 ATOM 2242 N N . SER B 1 99 ? 10.560 46.071 -26.470 1.00 12.92 ? 80 SER B N 1 ATOM 2243 C CA . SER B 1 99 ? 11.369 47.281 -26.495 1.00 13.91 ? 80 SER B CA 1 ATOM 2244 C C . SER B 1 99 ? 12.829 47.089 -26.895 1.00 23.00 ? 80 SER B C 1 ATOM 2245 O O . SER B 1 99 ? 13.624 47.998 -26.692 1.00 26.44 ? 80 SER B O 1 ATOM 2246 C CB . SER B 1 99 ? 11.354 47.949 -25.123 1.00 14.08 ? 80 SER B CB 1 ATOM 2247 O OG . SER B 1 99 ? 10.030 48.062 -24.654 1.00 28.96 ? 80 SER B OG 1 ATOM 2248 N N . LEU B 1 100 ? 13.191 45.923 -27.434 1.00 22.19 ? 81 LEU B N 1 ATOM 2249 C CA . LEU B 1 100 ? 14.590 45.602 -27.739 1.00 16.51 ? 81 LEU B CA 1 ATOM 2250 C C . LEU B 1 100 ? 14.697 44.988 -29.116 1.00 20.41 ? 81 LEU B C 1 ATOM 2251 O O . LEU B 1 100 ? 13.760 44.329 -29.570 1.00 23.39 ? 81 LEU B O 1 ATOM 2252 C CB . LEU B 1 100 ? 15.082 44.535 -26.791 1.00 15.10 ? 81 LEU B CB 1 ATOM 2253 C CG . LEU B 1 100 ? 15.221 44.871 -25.333 1.00 18.02 ? 81 LEU B CG 1 ATOM 2254 C CD1 . LEU B 1 100 ? 15.813 43.663 -24.639 1.00 16.84 ? 81 LEU B CD1 1 ATOM 2255 C CD2 . LEU B 1 100 ? 16.129 46.060 -25.227 1.00 24.86 ? 81 LEU B CD2 1 ATOM 2256 N N . TRP B 1 101 ? 15.837 45.145 -29.776 1.00 17.36 ? 82 TRP B N 1 ATOM 2257 C CA . TRP B 1 101 ? 16.101 44.281 -30.909 1.00 14.13 ? 82 TRP B CA 1 ATOM 2258 C C . TRP B 1 101 ? 16.352 42.875 -30.373 1.00 19.60 ? 82 TRP B C 1 ATOM 2259 O O . TRP B 1 101 ? 16.980 42.691 -29.322 1.00 18.20 ? 82 TRP B O 1 ATOM 2260 C CB . TRP B 1 101 ? 17.304 44.746 -31.696 1.00 14.79 ? 82 TRP B CB 1 ATOM 2261 C CG . TRP B 1 101 ? 17.650 43.819 -32.815 1.00 17.89 ? 82 TRP B CG 1 ATOM 2262 C CD1 . TRP B 1 101 ? 17.160 43.854 -34.084 1.00 17.78 ? 82 TRP B CD1 1 ATOM 2263 C CD2 . TRP B 1 101 ? 18.556 42.706 -32.764 1.00 20.38 ? 82 TRP B CD2 1 ATOM 2264 N NE1 . TRP B 1 101 ? 17.705 42.841 -34.830 1.00 14.62 ? 82 TRP B NE1 1 ATOM 2265 C CE2 . TRP B 1 101 ? 18.570 42.122 -34.046 1.00 17.29 ? 82 TRP B CE2 1 ATOM 2266 C CE3 . TRP B 1 101 ? 19.354 42.143 -31.755 1.00 22.17 ? 82 TRP B CE3 1 ATOM 2267 C CZ2 . TRP B 1 101 ? 19.353 40.998 -34.356 1.00 16.40 ? 82 TRP B CZ2 1 ATOM 2268 C CZ3 . TRP B 1 101 ? 20.135 41.022 -32.061 1.00 19.66 ? 82 TRP B CZ3 1 ATOM 2269 C CH2 . TRP B 1 101 ? 20.124 40.463 -33.356 1.00 16.23 ? 82 TRP B CH2 1 ATOM 2270 N N . VAL B 1 102 ? 15.865 41.888 -31.113 1.00 19.41 ? 83 VAL B N 1 ATOM 2271 C CA . VAL B 1 102 ? 15.999 40.480 -30.758 1.00 20.97 ? 83 VAL B CA 1 ATOM 2272 C C . VAL B 1 102 ? 16.348 39.709 -32.039 1.00 22.62 ? 83 VAL B C 1 ATOM 2273 O O . VAL B 1 102 ? 15.817 40.017 -33.109 1.00 26.27 ? 83 VAL B O 1 ATOM 2274 C CB . VAL B 1 102 ? 14.674 39.950 -30.149 1.00 22.54 ? 83 VAL B CB 1 ATOM 2275 C CG1 . VAL B 1 102 ? 14.512 38.445 -30.382 1.00 23.19 ? 83 VAL B CG1 1 ATOM 2276 C CG2 . VAL B 1 102 ? 14.576 40.309 -28.671 1.00 15.97 ? 83 VAL B CG2 1 ATOM 2277 N N . PRO B 1 103 ? 17.244 38.712 -31.945 1.00 21.64 ? 84 PRO B N 1 ATOM 2278 C CA . PRO B 1 103 ? 17.610 37.952 -33.149 1.00 18.37 ? 84 PRO B CA 1 ATOM 2279 C C . PRO B 1 103 ? 16.439 37.122 -33.664 1.00 19.28 ? 84 PRO B C 1 ATOM 2280 O O . PRO B 1 103 ? 15.672 36.618 -32.838 1.00 18.50 ? 84 PRO B O 1 ATOM 2281 C CB . PRO B 1 103 ? 18.747 37.039 -32.659 1.00 18.60 ? 84 PRO B CB 1 ATOM 2282 C CG . PRO B 1 103 ? 18.582 36.966 -31.173 1.00 18.12 ? 84 PRO B CG 1 ATOM 2283 C CD . PRO B 1 103 ? 17.987 38.276 -30.746 1.00 22.25 ? 84 PRO B CD 1 ATOM 2284 N N . ASP B 1 104 ? 16.314 36.998 -34.992 1.00 20.90 ? 85 ASP B N 1 ATOM 2285 C CA . ASP B 1 104 ? 15.195 36.287 -35.654 1.00 20.70 ? 85 ASP B CA 1 ATOM 2286 C C . ASP B 1 104 ? 15.443 34.774 -35.858 1.00 24.56 ? 85 ASP B C 1 ATOM 2287 O O . ASP B 1 104 ? 15.401 34.245 -36.982 1.00 19.99 ? 85 ASP B O 1 ATOM 2288 C CB . ASP B 1 104 ? 14.834 36.947 -36.997 1.00 23.28 ? 85 ASP B CB 1 ATOM 2289 C CG . ASP B 1 104 ? 15.997 36.931 -38.006 1.00 26.59 ? 85 ASP B CG 1 ATOM 2290 O OD1 . ASP B 1 104 ? 17.179 36.955 -37.582 1.00 29.47 ? 85 ASP B OD1 1 ATOM 2291 O OD2 . ASP B 1 104 ? 15.720 36.892 -39.227 1.00 24.68 ? 85 ASP B OD2 1 ATOM 2292 N N . LEU B 1 105 ? 15.684 34.080 -34.750 1.00 28.13 ? 86 LEU B N 1 ATOM 2293 C CA . LEU B 1 105 ? 15.989 32.661 -34.783 1.00 18.56 ? 86 LEU B CA 1 ATOM 2294 C C . LEU B 1 105 ? 14.724 31.849 -35.073 1.00 20.58 ? 86 LEU B C 1 ATOM 2295 O O . LEU B 1 105 ? 13.617 32.251 -34.693 1.00 22.51 ? 86 LEU B O 1 ATOM 2296 C CB . LEU B 1 105 ? 16.641 32.240 -33.465 1.00 15.40 ? 86 LEU B CB 1 ATOM 2297 C CG . LEU B 1 105 ? 17.916 33.025 -33.110 1.00 15.20 ? 86 LEU B CG 1 ATOM 2298 C CD1 . LEU B 1 105 ? 18.438 32.644 -31.713 1.00 16.97 ? 86 LEU B CD1 1 ATOM 2299 C CD2 . LEU B 1 105 ? 19.015 32.825 -34.153 1.00 11.81 ? 86 LEU B CD2 1 ATOM 2300 N N . ALA B 1 106 ? 14.892 30.731 -35.785 1.00 18.21 ? 87 ALA B N 1 ATOM 2301 C CA . ALA B 1 106 ? 13.795 29.812 -36.063 1.00 16.56 ? 87 ALA B CA 1 ATOM 2302 C C . ALA B 1 106 ? 14.320 28.396 -36.081 1.00 21.06 ? 87 ALA B C 1 ATOM 2303 O O . ALA B 1 106 ? 15.487 28.171 -36.389 1.00 23.99 ? 87 ALA B O 1 ATOM 2304 C CB . ALA B 1 106 ? 13.147 30.134 -37.374 1.00 17.70 ? 87 ALA B CB 1 ATOM 2305 N N . ALA B 1 107 ? 13.460 27.439 -35.743 1.00 23.99 ? 88 ALA B N 1 ATOM 2306 C CA . ALA B 1 107 ? 13.815 26.017 -35.831 1.00 26.21 ? 88 ALA B CA 1 ATOM 2307 C C . ALA B 1 107 ? 13.400 25.480 -37.196 1.00 25.19 ? 88 ALA B C 1 ATOM 2308 O O . ALA B 1 107 ? 12.202 25.395 -37.502 1.00 27.90 ? 88 ALA B O 1 ATOM 2309 C CB . ALA B 1 107 ? 13.142 25.229 -34.727 1.00 21.62 ? 88 ALA B CB 1 ATOM 2310 N N . TYR B 1 108 ? 14.386 25.119 -38.011 1.00 20.93 ? 89 TYR B N 1 ATOM 2311 C CA . TYR B 1 108 ? 14.138 24.727 -39.397 1.00 20.73 ? 89 TYR B CA 1 ATOM 2312 C C . TYR B 1 108 ? 13.240 23.496 -39.535 1.00 21.91 ? 89 TYR B C 1 ATOM 2313 O O . TYR B 1 108 ? 12.499 23.359 -40.515 1.00 23.29 ? 89 TYR B O 1 ATOM 2314 C CB . TYR B 1 108 ? 15.464 24.510 -40.131 1.00 22.33 ? 89 TYR B CB 1 ATOM 2315 C CG . TYR B 1 108 ? 16.108 25.795 -40.613 1.00 24.62 ? 89 TYR B CG 1 ATOM 2316 C CD1 . TYR B 1 108 ? 16.673 26.698 -39.716 1.00 28.01 ? 89 TYR B CD1 1 ATOM 2317 C CD2 . TYR B 1 108 ? 16.150 26.106 -41.967 1.00 23.21 ? 89 TYR B CD2 1 ATOM 2318 C CE1 . TYR B 1 108 ? 17.262 27.869 -40.154 1.00 21.69 ? 89 TYR B CE1 1 ATOM 2319 C CE2 . TYR B 1 108 ? 16.736 27.265 -42.417 1.00 20.98 ? 89 TYR B CE2 1 ATOM 2320 C CZ . TYR B 1 108 ? 17.286 28.144 -41.512 1.00 24.95 ? 89 TYR B CZ 1 ATOM 2321 O OH . TYR B 1 108 ? 17.873 29.298 -41.982 1.00 24.48 ? 89 TYR B OH 1 ATOM 2322 N N . ASN B 1 109 ? 13.302 22.597 -38.561 1.00 24.87 ? 90 ASN B N 1 ATOM 2323 C CA . ASN B 1 109 ? 12.510 21.362 -38.628 1.00 28.84 ? 90 ASN B CA 1 ATOM 2324 C C . ASN B 1 109 ? 11.339 21.335 -37.639 1.00 26.73 ? 90 ASN B C 1 ATOM 2325 O O . ASN B 1 109 ? 10.851 20.270 -37.239 1.00 28.25 ? 90 ASN B O 1 ATOM 2326 C CB . ASN B 1 109 ? 13.395 20.108 -38.493 1.00 20.35 ? 90 ASN B CB 1 ATOM 2327 C CG . ASN B 1 109 ? 14.169 20.057 -37.178 1.00 23.29 ? 90 ASN B CG 1 ATOM 2328 O OD1 . ASN B 1 109 ? 14.861 21.004 -36.794 1.00 22.69 ? 90 ASN B OD1 1 ATOM 2329 N ND2 . ASN B 1 109 ? 14.064 18.923 -36.487 1.00 34.14 ? 90 ASN B ND2 1 ATOM 2330 N N . ALA B 1 110 ? 10.896 22.522 -37.243 1.00 23.45 ? 91 ALA B N 1 ATOM 2331 C CA . ALA B 1 110 ? 9.719 22.637 -36.392 1.00 24.74 ? 91 ALA B CA 1 ATOM 2332 C C . ALA B 1 110 ? 8.485 22.436 -37.266 1.00 25.75 ? 91 ALA B C 1 ATOM 2333 O O . ALA B 1 110 ? 8.493 22.780 -38.453 1.00 24.69 ? 91 ALA B O 1 ATOM 2334 C CB . ALA B 1 110 ? 9.684 23.990 -35.717 1.00 27.09 ? 91 ALA B CB 1 ATOM 2335 N N . ILE B 1 111 ? 7.435 21.849 -36.706 1.00 21.45 ? 92 ILE B N 1 ATOM 2336 C CA . ILE B 1 111 ? 6.222 21.664 -37.487 1.00 22.43 ? 92 ILE B CA 1 ATOM 2337 C C . ILE B 1 111 ? 5.034 22.336 -36.813 1.00 24.03 ? 92 ILE B C 1 ATOM 2338 O O . ILE B 1 111 ? 3.884 22.135 -37.194 1.00 23.23 ? 92 ILE B O 1 ATOM 2339 C CB . ILE B 1 111 ? 5.925 20.181 -37.792 1.00 24.11 ? 92 ILE B CB 1 ATOM 2340 C CG1 . ILE B 1 111 ? 5.919 19.359 -36.509 1.00 28.25 ? 92 ILE B CG1 1 ATOM 2341 C CG2 . ILE B 1 111 ? 6.933 19.622 -38.782 1.00 24.26 ? 92 ILE B CG2 1 ATOM 2342 C CD1 . ILE B 1 111 ? 5.537 17.899 -36.727 1.00 36.10 ? 92 ILE B CD1 1 ATOM 2343 N N . SER B 1 112 ? 5.327 23.140 -35.801 1.00 26.01 ? 93 SER B N 1 ATOM 2344 C CA . SER B 1 112 ? 4.317 23.960 -35.136 1.00 21.67 ? 93 SER B CA 1 ATOM 2345 C C . SER B 1 112 ? 5.024 25.245 -34.728 1.00 22.47 ? 93 SER B C 1 ATOM 2346 O O . SER B 1 112 ? 6.250 25.259 -34.656 1.00 22.53 ? 93 SER B O 1 ATOM 2347 C CB . SER B 1 112 ? 3.780 23.228 -33.914 1.00 17.17 ? 93 SER B CB 1 ATOM 2348 O OG . SER B 1 112 ? 4.774 23.134 -32.909 1.00 25.49 ? 93 SER B OG 1 ATOM 2349 N N . LYS B 1 113 ? 4.288 26.325 -34.464 1.00 27.32 ? 94 LYS B N 1 ATOM 2350 C CA . LYS B 1 113 ? 4.962 27.556 -34.008 1.00 24.66 ? 94 LYS B CA 1 ATOM 2351 C C . LYS B 1 113 ? 5.322 27.467 -32.532 1.00 20.60 ? 94 LYS B C 1 ATOM 2352 O O . LYS B 1 113 ? 4.676 26.734 -31.786 1.00 24.11 ? 94 LYS B O 1 ATOM 2353 C CB . LYS B 1 113 ? 4.146 28.810 -34.312 1.00 25.61 ? 94 LYS B CB 1 ATOM 2354 C CG . LYS B 1 113 ? 2.834 28.905 -33.577 1.00 37.16 ? 94 LYS B CG 1 ATOM 2355 C CD . LYS B 1 113 ? 1.988 30.038 -34.169 1.00 44.65 ? 94 LYS B CD 1 ATOM 2356 C CE . LYS B 1 113 ? 2.787 31.341 -34.250 1.00 45.61 ? 94 LYS B CE 1 ATOM 2357 N NZ . LYS B 1 113 ? 1.936 32.549 -34.567 1.00 50.44 ? 94 LYS B NZ 1 ATOM 2358 N N . PRO B 1 114 ? 6.386 28.173 -32.113 1.00 22.24 ? 95 PRO B N 1 ATOM 2359 C CA . PRO B 1 114 ? 6.808 28.078 -30.704 1.00 22.49 ? 95 PRO B CA 1 ATOM 2360 C C . PRO B 1 114 ? 5.699 28.541 -29.778 1.00 26.37 ? 95 PRO B C 1 ATOM 2361 O O . PRO B 1 114 ? 5.124 29.592 -30.036 1.00 35.53 ? 95 PRO B O 1 ATOM 2362 C CB . PRO B 1 114 ? 7.966 29.068 -30.609 1.00 18.91 ? 95 PRO B CB 1 ATOM 2363 C CG . PRO B 1 114 ? 8.426 29.270 -32.032 1.00 22.15 ? 95 PRO B CG 1 ATOM 2364 C CD . PRO B 1 114 ? 7.233 29.097 -32.892 1.00 20.82 ? 95 PRO B CD 1 ATOM 2365 N N . GLU B 1 115 ? 5.376 27.757 -28.751 1.00 26.38 ? 96 GLU B N 1 ATOM 2366 C CA . GLU B 1 115 ? 4.421 28.175 -27.721 1.00 22.79 ? 96 GLU B CA 1 ATOM 2367 C C . GLU B 1 115 ? 5.205 28.699 -26.505 1.00 26.72 ? 96 GLU B C 1 ATOM 2368 O O . GLU B 1 115 ? 5.823 27.902 -25.755 1.00 24.56 ? 96 GLU B O 1 ATOM 2369 C CB . GLU B 1 115 ? 3.563 26.982 -27.312 1.00 19.49 ? 96 GLU B CB 1 ATOM 2370 C CG . GLU B 1 115 ? 2.411 27.299 -26.370 1.00 33.22 ? 96 GLU B CG 1 ATOM 2371 C CD . GLU B 1 115 ? 1.590 26.050 -26.030 1.00 45.96 ? 96 GLU B CD 1 ATOM 2372 O OE1 . GLU B 1 115 ? 1.741 25.037 -26.766 1.00 46.16 ? 96 GLU B OE1 1 ATOM 2373 O OE2 . GLU B 1 115 ? 0.811 26.070 -25.030 1.00 54.73 ? 96 GLU B OE2 1 ATOM 2374 N N . VAL B 1 116 ? 5.201 30.018 -26.298 1.00 18.06 ? 97 VAL B N 1 ATOM 2375 C CA . VAL B 1 116 ? 6.032 30.576 -25.220 1.00 21.68 ? 97 VAL B CA 1 ATOM 2376 C C . VAL B 1 116 ? 5.351 30.499 -23.853 1.00 21.69 ? 97 VAL B C 1 ATOM 2377 O O . VAL B 1 116 ? 4.324 31.124 -23.635 1.00 26.72 ? 97 VAL B O 1 ATOM 2378 C CB . VAL B 1 116 ? 6.493 32.011 -25.493 1.00 15.55 ? 97 VAL B CB 1 ATOM 2379 C CG1 . VAL B 1 116 ? 7.400 32.457 -24.377 1.00 14.01 ? 97 VAL B CG1 1 ATOM 2380 C CG2 . VAL B 1 116 ? 7.217 32.091 -26.823 1.00 13.60 ? 97 VAL B CG2 1 ATOM 2381 N N . LEU B 1 117 ? 5.941 29.737 -22.935 1.00 18.65 ? 98 LEU B N 1 ATOM 2382 C CA . LEU B 1 117 ? 5.311 29.435 -21.652 1.00 15.05 ? 98 LEU B CA 1 ATOM 2383 C C . LEU B 1 117 ? 5.542 30.505 -20.578 1.00 18.09 ? 98 LEU B C 1 ATOM 2384 O O . LEU B 1 117 ? 4.777 30.624 -19.625 1.00 17.90 ? 98 LEU B O 1 ATOM 2385 C CB . LEU B 1 117 ? 5.795 28.077 -21.142 1.00 17.32 ? 98 LEU B CB 1 ATOM 2386 C CG . LEU B 1 117 ? 5.497 26.864 -22.036 1.00 21.79 ? 98 LEU B CG 1 ATOM 2387 C CD1 . LEU B 1 117 ? 6.015 25.575 -21.418 1.00 16.40 ? 98 LEU B CD1 1 ATOM 2388 C CD2 . LEU B 1 117 ? 4.012 26.738 -22.378 1.00 19.41 ? 98 LEU B CD2 1 ATOM 2389 N N . THR B 1 118 ? 6.590 31.300 -20.742 1.00 20.52 ? 99 THR B N 1 ATOM 2390 C CA . THR B 1 118 ? 7.008 32.206 -19.682 1.00 19.23 ? 99 THR B CA 1 ATOM 2391 C C . THR B 1 118 ? 6.757 33.671 -20.070 1.00 20.66 ? 99 THR B C 1 ATOM 2392 O O . THR B 1 118 ? 6.485 33.949 -21.248 1.00 16.89 ? 99 THR B O 1 ATOM 2393 C CB . THR B 1 118 ? 8.492 31.993 -19.385 1.00 17.16 ? 99 THR B CB 1 ATOM 2394 O OG1 . THR B 1 118 ? 9.212 31.986 -20.631 1.00 23.47 ? 99 THR B OG1 1 ATOM 2395 C CG2 . THR B 1 118 ? 8.697 30.692 -18.669 1.00 16.73 ? 99 THR B CG2 1 ATOM 2396 N N . PRO B 1 119 ? 6.836 34.598 -19.079 1.00 17.08 ? 100 PRO B N 1 ATOM 2397 C CA . PRO B 1 119 ? 6.830 36.044 -19.310 1.00 15.35 ? 100 PRO B CA 1 ATOM 2398 C C . PRO B 1 119 ? 7.899 36.444 -20.310 1.00 16.78 ? 100 PRO B C 1 ATOM 2399 O O . PRO B 1 119 ? 9.014 35.895 -20.272 1.00 18.76 ? 100 PRO B O 1 ATOM 2400 C CB . PRO B 1 119 ? 7.215 36.599 -17.946 1.00 17.60 ? 100 PRO B CB 1 ATOM 2401 C CG . PRO B 1 119 ? 6.694 35.614 -16.972 1.00 13.65 ? 100 PRO B CG 1 ATOM 2402 C CD . PRO B 1 119 ? 6.788 34.285 -17.635 1.00 18.65 ? 100 PRO B CD 1 ATOM 2403 N N . GLN B 1 120 ? 7.575 37.383 -21.191 1.00 16.44 ? 101 GLN B N 1 ATOM 2404 C CA . GLN B 1 120 ? 8.492 37.713 -22.273 1.00 21.67 ? 101 GLN B CA 1 ATOM 2405 C C . GLN B 1 120 ? 9.435 38.880 -21.963 1.00 17.26 ? 101 GLN B C 1 ATOM 2406 O O . GLN B 1 120 ? 9.393 39.924 -22.616 1.00 20.06 ? 101 GLN B O 1 ATOM 2407 C CB . GLN B 1 120 ? 7.732 37.879 -23.594 1.00 17.45 ? 101 GLN B CB 1 ATOM 2408 C CG . GLN B 1 120 ? 7.251 36.547 -24.152 1.00 15.12 ? 101 GLN B CG 1 ATOM 2409 C CD . GLN B 1 120 ? 6.397 36.689 -25.410 1.00 24.36 ? 101 GLN B CD 1 ATOM 2410 O OE1 . GLN B 1 120 ? 6.675 37.525 -26.281 1.00 37.50 ? 101 GLN B OE1 1 ATOM 2411 N NE2 . GLN B 1 120 ? 5.342 35.877 -25.505 1.00 15.59 ? 101 GLN B NE2 1 ATOM 2412 N N . LEU B 1 121 ? 10.294 38.666 -20.967 1.00 15.68 ? 102 LEU B N 1 ATOM 2413 C CA . LEU B 1 121 ? 11.239 39.690 -20.504 1.00 17.10 ? 102 LEU B CA 1 ATOM 2414 C C . LEU B 1 121 ? 12.665 39.265 -20.782 1.00 16.87 ? 102 LEU B C 1 ATOM 2415 O O . LEU B 1 121 ? 13.000 38.083 -20.672 1.00 28.14 ? 102 LEU B O 1 ATOM 2416 C CB . LEU B 1 121 ? 11.090 39.920 -18.992 1.00 17.89 ? 102 LEU B CB 1 ATOM 2417 C CG . LEU B 1 121 ? 9.701 40.380 -18.551 1.00 20.00 ? 102 LEU B CG 1 ATOM 2418 C CD1 . LEU B 1 121 ? 9.607 40.554 -17.029 1.00 21.10 ? 102 LEU B CD1 1 ATOM 2419 C CD2 . LEU B 1 121 ? 9.359 41.665 -19.277 1.00 14.59 ? 102 LEU B CD2 1 ATOM 2420 N N . ALA B 1 122 ? 13.509 40.224 -21.130 1.00 14.79 ? 103 ALA B N 1 ATOM 2421 C CA . ALA B 1 122 ? 14.938 39.975 -21.248 1.00 13.12 ? 103 ALA B CA 1 ATOM 2422 C C . ALA B 1 122 ? 15.710 40.615 -20.081 1.00 17.93 ? 103 ALA B C 1 ATOM 2423 O O . ALA B 1 122 ? 15.282 41.627 -19.477 1.00 15.11 ? 103 ALA B O 1 ATOM 2424 C CB . ALA B 1 122 ? 15.446 40.490 -22.563 1.00 11.21 ? 103 ALA B CB 1 ATOM 2425 N N . HIS B 1 123 ? 16.864 40.031 -19.786 1.00 14.92 ? 104 HIS B N 1 ATOM 2426 C CA . HIS B 1 123 ? 17.756 40.549 -18.764 1.00 17.76 ? 104 HIS B CA 1 ATOM 2427 C C . HIS B 1 123 ? 18.802 41.423 -19.450 1.00 22.66 ? 104 HIS B C 1 ATOM 2428 O O . HIS B 1 123 ? 19.398 41.008 -20.445 1.00 22.41 ? 104 HIS B O 1 ATOM 2429 C CB . HIS B 1 123 ? 18.417 39.384 -18.061 1.00 24.77 ? 104 HIS B CB 1 ATOM 2430 C CG . HIS B 1 123 ? 19.086 39.749 -16.775 1.00 29.36 ? 104 HIS B CG 1 ATOM 2431 N ND1 . HIS B 1 123 ? 20.460 39.841 -16.660 1.00 40.52 ? 104 HIS B ND1 1 ATOM 2432 C CD2 . HIS B 1 123 ? 18.582 39.988 -15.551 1.00 34.67 ? 104 HIS B CD2 1 ATOM 2433 C CE1 . HIS B 1 123 ? 20.769 40.154 -15.414 1.00 34.78 ? 104 HIS B CE1 1 ATOM 2434 N NE2 . HIS B 1 123 ? 19.656 40.249 -14.717 1.00 43.71 ? 104 HIS B NE2 1 ATOM 2435 N N . VAL B 1 124 ? 19.000 42.642 -18.948 1.00 19.53 ? 105 VAL B N 1 ATOM 2436 C CA . VAL B 1 124 ? 19.967 43.560 -19.531 1.00 18.43 ? 105 VAL B CA 1 ATOM 2437 C C . VAL B 1 124 ? 20.934 44.046 -18.468 1.00 22.16 ? 105 VAL B C 1 ATOM 2438 O O . VAL B 1 124 ? 20.525 44.527 -17.419 1.00 23.23 ? 105 VAL B O 1 ATOM 2439 C CB . VAL B 1 124 ? 19.301 44.799 -20.139 1.00 21.82 ? 105 VAL B CB 1 ATOM 2440 C CG1 . VAL B 1 124 ? 20.350 45.651 -20.888 1.00 18.06 ? 105 VAL B CG1 1 ATOM 2441 C CG2 . VAL B 1 124 ? 18.166 44.404 -21.052 1.00 18.72 ? 105 VAL B CG2 1 ATOM 2442 N N . VAL B 1 125 ? 22.223 43.935 -18.760 1.00 23.70 ? 106 VAL B N 1 ATOM 2443 C CA . VAL B 1 125 ? 23.278 44.353 -17.841 1.00 27.34 ? 106 VAL B CA 1 ATOM 2444 C C . VAL B 1 125 ? 23.838 45.685 -18.345 1.00 26.34 ? 106 VAL B C 1 ATOM 2445 O O . VAL B 1 125 ? 23.806 45.929 -19.546 1.00 28.17 ? 106 VAL B O 1 ATOM 2446 C CB . VAL B 1 125 ? 24.389 43.273 -17.778 1.00 25.85 ? 106 VAL B CB 1 ATOM 2447 C CG1 . VAL B 1 125 ? 25.588 43.759 -16.972 1.00 23.87 ? 106 VAL B CG1 1 ATOM 2448 C CG2 . VAL B 1 125 ? 23.833 41.996 -17.188 1.00 28.59 ? 106 VAL B CG2 1 ATOM 2449 N N . SER B 1 126 ? 24.339 46.534 -17.444 1.00 21.71 ? 107 SER B N 1 ATOM 2450 C CA . SER B 1 126 ? 24.806 47.880 -17.802 1.00 25.01 ? 107 SER B CA 1 ATOM 2451 C C . SER B 1 126 ? 25.842 47.972 -18.932 1.00 26.32 ? 107 SER B C 1 ATOM 2452 O O . SER B 1 126 ? 25.977 49.029 -19.572 1.00 26.46 ? 107 SER B O 1 ATOM 2453 C CB . SER B 1 126 ? 25.347 48.615 -16.577 1.00 26.23 ? 107 SER B CB 1 ATOM 2454 O OG . SER B 1 126 ? 26.367 47.870 -15.957 1.00 25.74 ? 107 SER B OG 1 ATOM 2455 N N . ASP B 1 127 ? 26.577 46.892 -19.180 1.00 23.43 ? 108 ASP B N 1 ATOM 2456 C CA . ASP B 1 127 ? 27.531 46.907 -20.294 1.00 28.83 ? 108 ASP B CA 1 ATOM 2457 C C . ASP B 1 127 ? 26.888 46.713 -21.685 1.00 34.25 ? 108 ASP B C 1 ATOM 2458 O O . ASP B 1 127 ? 27.539 46.934 -22.706 1.00 37.79 ? 108 ASP B O 1 ATOM 2459 C CB . ASP B 1 127 ? 28.670 45.897 -20.090 1.00 30.77 ? 108 ASP B CB 1 ATOM 2460 C CG . ASP B 1 127 ? 28.178 44.446 -19.985 1.00 41.35 ? 108 ASP B CG 1 ATOM 2461 O OD1 . ASP B 1 127 ? 26.984 44.190 -20.297 1.00 44.75 ? 108 ASP B OD1 1 ATOM 2462 O OD2 . ASP B 1 127 ? 28.992 43.559 -19.596 1.00 34.12 ? 108 ASP B OD2 1 ATOM 2463 N N . GLY B 1 128 ? 25.627 46.289 -21.725 1.00 25.14 ? 109 GLY B N 1 ATOM 2464 C CA . GLY B 1 128 ? 24.949 46.097 -22.989 1.00 21.21 ? 109 GLY B CA 1 ATOM 2465 C C . GLY B 1 128 ? 24.677 44.637 -23.287 1.00 28.73 ? 109 GLY B C 1 ATOM 2466 O O . GLY B 1 128 ? 24.199 44.294 -24.370 1.00 30.09 ? 109 GLY B O 1 ATOM 2467 N N . GLU B 1 129 ? 24.972 43.769 -22.327 1.00 26.96 ? 110 GLU B N 1 ATOM 2468 C CA . GLU B 1 129 ? 24.751 42.339 -22.511 1.00 25.65 ? 110 GLU B CA 1 ATOM 2469 C C . GLU B 1 129 ? 23.295 41.950 -22.260 1.00 25.79 ? 110 GLU B C 1 ATOM 2470 O O . GLU B 1 129 ? 22.726 42.244 -21.209 1.00 26.26 ? 110 GLU B O 1 ATOM 2471 C CB . GLU B 1 129 ? 25.659 41.530 -21.580 1.00 36.48 ? 110 GLU B CB 1 ATOM 2472 C CG . GLU B 1 129 ? 27.045 41.266 -22.141 1.00 47.81 ? 110 GLU B CG 1 ATOM 2473 C CD . GLU B 1 129 ? 27.034 40.232 -23.275 1.00 63.00 ? 110 GLU B CD 1 ATOM 2474 O OE1 . GLU B 1 129 ? 26.415 39.143 -23.086 1.00 54.98 ? 110 GLU B OE1 1 ATOM 2475 O OE2 . GLU B 1 129 ? 27.638 40.519 -24.351 1.00 58.90 ? 110 GLU B OE2 1 ATOM 2476 N N . VAL B 1 130 ? 22.699 41.264 -23.223 1.00 28.05 ? 111 VAL B N 1 ATOM 2477 C CA . VAL B 1 130 ? 21.304 40.880 -23.130 1.00 20.06 ? 111 VAL B CA 1 ATOM 2478 C C . VAL B 1 130 ? 21.201 39.365 -23.061 1.00 20.83 ? 111 VAL B C 1 ATOM 2479 O O . VAL B 1 130 ? 21.909 38.658 -23.780 1.00 23.17 ? 111 VAL B O 1 ATOM 2480 C CB . VAL B 1 130 ? 20.522 41.394 -24.354 1.00 16.99 ? 111 VAL B CB 1 ATOM 2481 C CG1 . VAL B 1 130 ? 19.038 41.111 -24.200 1.00 14.25 ? 111 VAL B CG1 1 ATOM 2482 C CG2 . VAL B 1 130 ? 20.760 42.864 -24.530 1.00 18.09 ? 111 VAL B CG2 1 ATOM 2483 N N . GLN B 1 131 ? 20.326 38.868 -22.193 1.00 19.44 ? 112 GLN B N 1 ATOM 2484 C CA . GLN B 1 131 ? 20.001 37.452 -22.193 1.00 21.11 ? 112 GLN B CA 1 ATOM 2485 C C . GLN B 1 131 ? 18.491 37.246 -22.177 1.00 21.11 ? 112 GLN B C 1 ATOM 2486 O O . GLN B 1 131 ? 17.794 37.790 -21.332 1.00 24.24 ? 112 GLN B O 1 ATOM 2487 C CB . GLN B 1 131 ? 20.635 36.741 -21.007 1.00 22.08 ? 112 GLN B CB 1 ATOM 2488 C CG . GLN B 1 131 ? 20.335 35.260 -20.997 1.00 33.81 ? 112 GLN B CG 1 ATOM 2489 C CD . GLN B 1 131 ? 20.997 34.537 -19.844 1.00 46.92 ? 112 GLN B CD 1 ATOM 2490 O OE1 . GLN B 1 131 ? 22.138 34.846 -19.476 1.00 41.56 ? 112 GLN B OE1 1 ATOM 2491 N NE2 . GLN B 1 131 ? 20.279 33.565 -19.255 1.00 51.06 ? 112 GLN B NE2 1 ATOM 2492 N N . TYR B 1 132 ? 17.988 36.466 -23.124 1.00 22.41 ? 113 TYR B N 1 ATOM 2493 C CA . TYR B 1 132 ? 16.567 36.152 -23.194 1.00 19.10 ? 113 TYR B CA 1 ATOM 2494 C C . TYR B 1 132 ? 16.406 34.630 -23.202 1.00 23.39 ? 113 TYR B C 1 ATOM 2495 O O . TYR B 1 132 ? 16.862 33.948 -24.124 1.00 25.95 ? 113 TYR B O 1 ATOM 2496 C CB . TYR B 1 132 ? 15.956 36.783 -24.451 1.00 18.07 ? 113 TYR B CB 1 ATOM 2497 C CG . TYR B 1 132 ? 14.494 36.454 -24.684 1.00 13.79 ? 113 TYR B CG 1 ATOM 2498 C CD1 . TYR B 1 132 ? 13.582 36.492 -23.636 1.00 11.43 ? 113 TYR B CD1 1 ATOM 2499 C CD2 . TYR B 1 132 ? 14.024 36.144 -25.956 1.00 10.55 ? 113 TYR B CD2 1 ATOM 2500 C CE1 . TYR B 1 132 ? 12.247 36.207 -23.839 1.00 11.18 ? 113 TYR B CE1 1 ATOM 2501 C CE2 . TYR B 1 132 ? 12.698 35.847 -26.178 1.00 11.00 ? 113 TYR B CE2 1 ATOM 2502 C CZ . TYR B 1 132 ? 11.806 35.870 -25.105 1.00 15.36 ? 113 TYR B CZ 1 ATOM 2503 O OH . TYR B 1 132 ? 10.453 35.582 -25.279 1.00 18.76 ? 113 TYR B OH 1 ATOM 2504 N N . THR B 1 133 ? 15.757 34.102 -22.167 1.00 24.93 ? 114 THR B N 1 ATOM 2505 C CA . THR B 1 133 ? 15.634 32.650 -21.973 1.00 22.08 ? 114 THR B CA 1 ATOM 2506 C C . THR B 1 133 ? 14.166 32.225 -21.772 1.00 17.72 ? 114 THR B C 1 ATOM 2507 O O . THR B 1 133 ? 13.723 31.960 -20.652 1.00 16.86 ? 114 THR B O 1 ATOM 2508 C CB . THR B 1 133 ? 16.480 32.179 -20.748 1.00 24.85 ? 114 THR B CB 1 ATOM 2509 O OG1 . THR B 1 133 ? 17.783 32.802 -20.759 1.00 27.81 ? 114 THR B OG1 1 ATOM 2510 C CG2 . THR B 1 133 ? 16.617 30.656 -20.717 1.00 18.67 ? 114 THR B CG2 1 ATOM 2511 N N . PRO B 1 134 ? 13.395 32.163 -22.863 1.00 16.36 ? 115 PRO B N 1 ATOM 2512 C CA . PRO B 1 134 ? 11.999 31.738 -22.704 1.00 15.76 ? 115 PRO B CA 1 ATOM 2513 C C . PRO B 1 134 ? 11.880 30.222 -22.608 1.00 17.49 ? 115 PRO B C 1 ATOM 2514 O O . PRO B 1 134 ? 12.683 29.490 -23.205 1.00 18.65 ? 115 PRO B O 1 ATOM 2515 C CB . PRO B 1 134 ? 11.350 32.213 -24.004 1.00 13.43 ? 115 PRO B CB 1 ATOM 2516 C CG . PRO B 1 134 ? 12.472 32.203 -24.995 1.00 12.22 ? 115 PRO B CG 1 ATOM 2517 C CD . PRO B 1 134 ? 13.711 32.561 -24.247 1.00 14.00 ? 115 PRO B CD 1 ATOM 2518 N N . SER B 1 135 ? 10.887 29.741 -21.872 1.00 15.97 ? 116 SER B N 1 ATOM 2519 C CA . SER B 1 135 ? 10.573 28.315 -21.930 1.00 16.54 ? 116 SER B CA 1 ATOM 2520 C C . SER B 1 135 ? 9.603 28.055 -23.079 1.00 16.76 ? 116 SER B C 1 ATOM 2521 O O . SER B 1 135 ? 8.573 28.711 -23.191 1.00 18.45 ? 116 SER B O 1 ATOM 2522 C CB . SER B 1 135 ? 9.971 27.835 -20.619 1.00 18.44 ? 116 SER B CB 1 ATOM 2523 O OG . SER B 1 135 ? 9.781 26.426 -20.639 1.00 23.73 ? 116 SER B OG 1 ATOM 2524 N N . ILE B 1 136 ? 9.927 27.089 -23.928 1.00 17.98 ? 117 ILE B N 1 ATOM 2525 C CA . ILE B 1 136 ? 9.160 26.859 -25.151 1.00 17.68 ? 117 ILE B CA 1 ATOM 2526 C C . ILE B 1 136 ? 8.708 25.413 -25.314 1.00 19.47 ? 117 ILE B C 1 ATOM 2527 O O . ILE B 1 136 ? 9.504 24.482 -25.178 1.00 25.19 ? 117 ILE B O 1 ATOM 2528 C CB . ILE B 1 136 ? 9.991 27.252 -26.391 1.00 18.26 ? 117 ILE B CB 1 ATOM 2529 C CG1 . ILE B 1 136 ? 10.303 28.754 -26.364 1.00 16.91 ? 117 ILE B CG1 1 ATOM 2530 C CG2 . ILE B 1 136 ? 9.288 26.839 -27.673 1.00 15.41 ? 117 ILE B CG2 1 ATOM 2531 C CD1 . ILE B 1 136 ? 11.234 29.211 -27.459 1.00 14.36 ? 117 ILE B CD1 1 ATOM 2532 N N . ARG B 1 137 ? 7.426 25.220 -25.604 1.00 21.47 ? 118 ARG B N 1 ATOM 2533 C CA . ARG B 1 137 ? 6.946 23.919 -26.051 1.00 21.57 ? 118 ARG B CA 1 ATOM 2534 C C . ARG B 1 137 ? 6.802 23.947 -27.578 1.00 19.72 ? 118 ARG B C 1 ATOM 2535 O O . ARG B 1 137 ? 6.128 24.822 -28.121 1.00 19.32 ? 118 ARG B O 1 ATOM 2536 C CB . ARG B 1 137 ? 5.605 23.576 -25.391 1.00 21.72 ? 118 ARG B CB 1 ATOM 2537 C CG . ARG B 1 137 ? 4.916 22.375 -26.019 1.00 24.90 ? 118 ARG B CG 1 ATOM 2538 C CD . ARG B 1 137 ? 3.905 21.738 -25.095 1.00 33.17 ? 118 ARG B CD 1 ATOM 2539 N NE . ARG B 1 137 ? 3.385 20.488 -25.650 1.00 38.29 ? 118 ARG B NE 1 ATOM 2540 C CZ . ARG B 1 137 ? 2.567 19.665 -25.006 1.00 39.24 ? 118 ARG B CZ 1 ATOM 2541 N NH1 . ARG B 1 137 ? 2.180 19.940 -23.763 1.00 40.90 ? 118 ARG B NH1 1 ATOM 2542 N NH2 . ARG B 1 137 ? 2.157 18.550 -25.595 1.00 50.94 ? 118 ARG B NH2 1 ATOM 2543 N N . GLN B 1 138 ? 7.430 22.997 -28.265 1.00 18.28 ? 119 GLN B N 1 ATOM 2544 C CA . GLN B 1 138 ? 7.360 22.922 -29.724 1.00 20.56 ? 119 GLN B CA 1 ATOM 2545 C C . GLN B 1 138 ? 7.378 21.475 -30.268 1.00 26.77 ? 119 GLN B C 1 ATOM 2546 O O . GLN B 1 138 ? 8.015 20.588 -29.695 1.00 27.41 ? 119 GLN B O 1 ATOM 2547 C CB . GLN B 1 138 ? 8.504 23.741 -30.345 1.00 20.67 ? 119 GLN B CB 1 ATOM 2548 C CG . GLN B 1 138 ? 8.279 24.154 -31.802 1.00 20.54 ? 119 GLN B CG 1 ATOM 2549 C CD . GLN B 1 138 ? 9.151 25.336 -32.206 1.00 22.15 ? 119 GLN B CD 1 ATOM 2550 O OE1 . GLN B 1 138 ? 10.172 25.619 -31.572 1.00 26.18 ? 119 GLN B OE1 1 ATOM 2551 N NE2 . GLN B 1 138 ? 8.745 26.044 -33.253 1.00 24.62 ? 119 GLN B NE2 1 ATOM 2552 N N . ARG B 1 139 ? 6.689 21.248 -31.386 1.00 26.70 ? 120 ARG B N 1 ATOM 2553 C CA . ARG B 1 139 ? 6.689 19.945 -32.044 1.00 21.85 ? 120 ARG B CA 1 ATOM 2554 C C . ARG B 1 139 ? 7.687 19.914 -33.224 1.00 26.68 ? 120 ARG B C 1 ATOM 2555 O O . ARG B 1 139 ? 7.725 20.848 -34.033 1.00 30.74 ? 120 ARG B O 1 ATOM 2556 C CB . ARG B 1 139 ? 5.269 19.608 -32.497 1.00 24.32 ? 120 ARG B CB 1 ATOM 2557 C CG . ARG B 1 139 ? 5.082 18.150 -32.869 1.00 40.34 ? 120 ARG B CG 1 ATOM 2558 C CD . ARG B 1 139 ? 3.632 17.657 -32.808 1.00 40.52 ? 120 ARG B CD 1 ATOM 2559 N NE . ARG B 1 139 ? 3.570 16.206 -33.037 1.00 46.04 ? 120 ARG B NE 1 ATOM 2560 C CZ . ARG B 1 139 ? 3.669 15.285 -32.070 1.00 58.55 ? 120 ARG B CZ 1 ATOM 2561 N NH1 . ARG B 1 139 ? 3.811 15.665 -30.803 1.00 56.21 ? 120 ARG B NH1 1 ATOM 2562 N NH2 . ARG B 1 139 ? 3.618 13.984 -32.360 1.00 51.98 ? 120 ARG B NH2 1 ATOM 2563 N N . PHE B 1 140 ? 8.508 18.864 -33.308 1.00 26.19 ? 121 PHE B N 1 ATOM 2564 C CA . PHE B 1 140 ? 9.523 18.747 -34.374 1.00 26.90 ? 121 PHE B CA 1 ATOM 2565 C C . PHE B 1 140 ? 9.405 17.493 -35.229 1.00 31.01 ? 121 PHE B C 1 ATOM 2566 O O . PHE B 1 140 ? 8.732 16.526 -34.871 1.00 29.78 ? 121 PHE B O 1 ATOM 2567 C CB . PHE B 1 140 ? 10.937 18.766 -33.801 1.00 27.00 ? 121 PHE B CB 1 ATOM 2568 C CG . PHE B 1 140 ? 11.258 20.003 -33.056 1.00 25.27 ? 121 PHE B CG 1 ATOM 2569 C CD1 . PHE B 1 140 ? 10.928 20.121 -31.712 1.00 23.65 ? 121 PHE B CD1 1 ATOM 2570 C CD2 . PHE B 1 140 ? 11.886 21.058 -33.701 1.00 26.73 ? 121 PHE B CD2 1 ATOM 2571 C CE1 . PHE B 1 140 ? 11.213 21.271 -31.014 1.00 26.85 ? 121 PHE B CE1 1 ATOM 2572 C CE2 . PHE B 1 140 ? 12.184 22.226 -33.018 1.00 29.32 ? 121 PHE B CE2 1 ATOM 2573 C CZ . PHE B 1 140 ? 11.846 22.337 -31.665 1.00 31.80 ? 121 PHE B CZ 1 ATOM 2574 N N . SER B 1 141 ? 10.095 17.523 -36.360 1.00 29.81 ? 122 SER B N 1 ATOM 2575 C CA . SER B 1 141 ? 10.172 16.379 -37.250 1.00 30.11 ? 122 SER B CA 1 ATOM 2576 C C . SER B 1 141 ? 11.605 15.895 -37.243 1.00 31.45 ? 122 SER B C 1 ATOM 2577 O O . SER B 1 141 ? 12.506 16.622 -37.665 1.00 35.08 ? 122 SER B O 1 ATOM 2578 C CB . SER B 1 141 ? 9.782 16.779 -38.666 1.00 28.77 ? 122 SER B CB 1 ATOM 2579 O OG . SER B 1 141 ? 10.392 15.913 -39.603 1.00 27.13 ? 122 SER B OG 1 ATOM 2580 N N . CYS B 1 142 ? 11.821 14.677 -36.752 1.00 34.01 ? 123 CYS B N 1 ATOM 2581 C CA . CYS B 1 142 ? 13.177 14.136 -36.622 1.00 41.10 ? 123 CYS B CA 1 ATOM 2582 C C . CYS B 1 142 ? 13.216 12.613 -36.552 1.00 37.28 ? 123 CYS B C 1 ATOM 2583 O O . CYS B 1 142 ? 12.174 11.950 -36.588 1.00 39.65 ? 123 CYS B O 1 ATOM 2584 C CB . CYS B 1 142 ? 13.871 14.737 -35.398 1.00 41.37 ? 123 CYS B CB 1 ATOM 2585 S SG . CYS B 1 142 ? 12.956 14.467 -33.860 1.00 52.15 ? 123 CYS B SG 1 ATOM 2586 N N . ASP B 1 143 ? 14.422 12.064 -36.448 1.00 30.51 ? 124 ASP B N 1 ATOM 2587 C CA . ASP B 1 143 ? 14.580 10.617 -36.412 1.00 39.64 ? 124 ASP B CA 1 ATOM 2588 C C . ASP B 1 143 ? 14.278 10.045 -35.017 1.00 41.61 ? 124 ASP B C 1 ATOM 2589 O O . ASP B 1 143 ? 15.004 10.314 -34.052 1.00 38.34 ? 124 ASP B O 1 ATOM 2590 C CB . ASP B 1 143 ? 15.983 10.218 -36.878 1.00 38.82 ? 124 ASP B CB 1 ATOM 2591 C CG . ASP B 1 143 ? 16.076 8.755 -37.278 1.00 46.54 ? 124 ASP B CG 1 ATOM 2592 O OD1 . ASP B 1 143 ? 15.025 8.059 -37.319 1.00 49.91 ? 124 ASP B OD1 1 ATOM 2593 O OD2 . ASP B 1 143 ? 17.207 8.310 -37.571 1.00 51.94 ? 124 ASP B OD2 1 ATOM 2594 N N . VAL B 1 144 ? 13.210 9.250 -34.938 1.00 36.86 ? 125 VAL B N 1 ATOM 2595 C CA . VAL B 1 144 ? 12.689 8.733 -33.681 1.00 35.65 ? 125 VAL B CA 1 ATOM 2596 C C . VAL B 1 144 ? 12.976 7.225 -33.516 1.00 42.94 ? 125 VAL B C 1 ATOM 2597 O O . VAL B 1 144 ? 12.857 6.667 -32.421 1.00 45.03 ? 125 VAL B O 1 ATOM 2598 C CB . VAL B 1 144 ? 11.171 9.023 -33.598 1.00 38.19 ? 125 VAL B CB 1 ATOM 2599 C CG1 . VAL B 1 144 ? 10.578 8.559 -32.288 1.00 42.22 ? 125 VAL B CG1 1 ATOM 2600 C CG2 . VAL B 1 144 ? 10.921 10.490 -33.768 1.00 38.70 ? 125 VAL B CG2 1 ATOM 2601 N N . SER B 1 145 ? 13.373 6.577 -34.607 1.00 43.17 ? 126 SER B N 1 ATOM 2602 C CA . SER B 1 145 ? 13.670 5.144 -34.598 1.00 42.80 ? 126 SER B CA 1 ATOM 2603 C C . SER B 1 145 ? 14.653 4.719 -33.490 1.00 39.10 ? 126 SER B C 1 ATOM 2604 O O . SER B 1 145 ? 15.720 5.329 -33.308 1.00 35.92 ? 126 SER B O 1 ATOM 2605 C CB . SER B 1 145 ? 14.236 4.724 -35.953 1.00 50.00 ? 126 SER B CB 1 ATOM 2606 O OG . SER B 1 145 ? 15.459 5.401 -36.205 1.00 54.02 ? 126 SER B OG 1 ATOM 2607 N N . GLY B 1 146 ? 14.282 3.667 -32.760 1.00 35.00 ? 127 GLY B N 1 ATOM 2608 C CA . GLY B 1 146 ? 15.116 3.123 -31.708 1.00 38.83 ? 127 GLY B CA 1 ATOM 2609 C C . GLY B 1 146 ? 14.889 3.803 -30.377 1.00 42.39 ? 127 GLY B C 1 ATOM 2610 O O . GLY B 1 146 ? 15.715 3.726 -29.466 1.00 40.25 ? 127 GLY B O 1 ATOM 2611 N N . VAL B 1 147 ? 13.755 4.481 -30.264 1.00 46.89 ? 128 VAL B N 1 ATOM 2612 C CA . VAL B 1 147 ? 13.422 5.177 -29.027 1.00 48.81 ? 128 VAL B CA 1 ATOM 2613 C C . VAL B 1 147 ? 13.164 4.154 -27.900 1.00 48.12 ? 128 VAL B C 1 ATOM 2614 O O . VAL B 1 147 ? 13.399 4.441 -26.718 1.00 42.22 ? 128 VAL B O 1 ATOM 2615 C CB . VAL B 1 147 ? 12.225 6.159 -29.228 1.00 40.05 ? 128 VAL B CB 1 ATOM 2616 C CG1 . VAL B 1 147 ? 10.968 5.412 -29.703 1.00 38.35 ? 128 VAL B CG1 1 ATOM 2617 C CG2 . VAL B 1 147 ? 11.951 6.936 -27.957 1.00 37.10 ? 128 VAL B CG2 1 ATOM 2618 N N . ASP B 1 148 ? 12.720 2.955 -28.285 1.00 45.27 ? 129 ASP B N 1 ATOM 2619 C CA . ASP B 1 148 ? 12.422 1.892 -27.325 1.00 47.69 ? 129 ASP B CA 1 ATOM 2620 C C . ASP B 1 148 ? 13.565 0.852 -27.227 1.00 39.71 ? 129 ASP B C 1 ATOM 2621 O O . ASP B 1 148 ? 13.346 -0.325 -27.019 1.00 36.96 ? 129 ASP B O 1 ATOM 2622 C CB . ASP B 1 148 ? 11.081 1.234 -27.681 1.00 52.21 ? 129 ASP B CB 1 ATOM 2623 C CG . ASP B 1 148 ? 10.273 0.841 -26.446 1.00 74.38 ? 129 ASP B CG 1 ATOM 2624 O OD1 . ASP B 1 148 ? 10.875 0.317 -25.472 1.00 77.01 ? 129 ASP B OD1 1 ATOM 2625 O OD2 . ASP B 1 148 ? 9.036 1.064 -26.447 1.00 76.62 ? 129 ASP B OD2 1 ATOM 2626 N N . THR B 1 149 ? 14.791 1.334 -27.355 1.00 43.87 ? 130 THR B N 1 ATOM 2627 C CA . THR B 1 149 ? 15.990 0.517 -27.465 1.00 44.34 ? 130 THR B CA 1 ATOM 2628 C C . THR B 1 149 ? 17.005 0.990 -26.422 1.00 46.92 ? 130 THR B C 1 ATOM 2629 O O . THR B 1 149 ? 16.926 2.120 -25.951 1.00 52.54 ? 130 THR B O 1 ATOM 2630 C CB . THR B 1 149 ? 16.561 0.674 -28.890 1.00 41.40 ? 130 THR B CB 1 ATOM 2631 O OG1 . THR B 1 149 ? 15.691 -0.008 -29.796 1.00 45.45 ? 130 THR B OG1 1 ATOM 2632 C CG2 . THR B 1 149 ? 17.988 0.121 -29.035 1.00 48.61 ? 130 THR B CG2 1 ATOM 2633 N N . GLU B 1 150 ? 17.958 0.146 -26.052 1.00 46.73 ? 131 GLU B N 1 ATOM 2634 C CA . GLU B 1 150 ? 18.933 0.542 -25.052 1.00 52.92 ? 131 GLU B CA 1 ATOM 2635 C C . GLU B 1 150 ? 19.847 1.689 -25.509 1.00 49.99 ? 131 GLU B C 1 ATOM 2636 O O . GLU B 1 150 ? 20.345 2.465 -24.680 1.00 46.32 ? 131 GLU B O 1 ATOM 2637 C CB . GLU B 1 150 ? 19.760 -0.667 -24.634 1.00 57.04 ? 131 GLU B CB 1 ATOM 2638 C CG . GLU B 1 150 ? 20.508 -0.479 -23.339 1.00 64.19 ? 131 GLU B CG 1 ATOM 2639 C CD . GLU B 1 150 ? 21.639 -1.464 -23.201 1.00 80.41 ? 131 GLU B CD 1 ATOM 2640 O OE1 . GLU B 1 150 ? 22.314 -1.719 -24.221 1.00 82.97 ? 131 GLU B OE1 1 ATOM 2641 O OE2 . GLU B 1 150 ? 21.844 -1.989 -22.085 1.00 93.70 ? 131 GLU B OE2 1 ATOM 2642 N N . SER B 1 151 ? 20.051 1.803 -26.821 1.00 46.83 ? 132 SER B N 1 ATOM 2643 C CA . SER B 1 151 ? 20.912 2.859 -27.389 1.00 52.14 ? 132 SER B CA 1 ATOM 2644 C C . SER B 1 151 ? 20.176 4.181 -27.753 1.00 48.93 ? 132 SER B C 1 ATOM 2645 O O . SER B 1 151 ? 20.807 5.222 -27.993 1.00 47.67 ? 132 SER B O 1 ATOM 2646 C CB . SER B 1 151 ? 21.670 2.316 -28.601 1.00 46.26 ? 132 SER B CB 1 ATOM 2647 O OG . SER B 1 151 ? 20.771 1.688 -29.500 1.00 60.44 ? 132 SER B OG 1 ATOM 2648 N N . GLY B 1 152 ? 18.849 4.123 -27.810 1.00 42.96 ? 133 GLY B N 1 ATOM 2649 C CA . GLY B 1 152 ? 18.032 5.315 -27.928 1.00 38.69 ? 133 GLY B CA 1 ATOM 2650 C C . GLY B 1 152 ? 17.924 5.887 -29.327 1.00 47.12 ? 133 GLY B C 1 ATOM 2651 O O . GLY B 1 152 ? 18.616 5.434 -30.250 1.00 44.49 ? 133 GLY B O 1 ATOM 2652 N N . ALA B 1 153 ? 17.041 6.881 -29.482 1.00 52.08 ? 134 ALA B N 1 ATOM 2653 C CA . ALA B 1 153 ? 16.926 7.655 -30.727 1.00 41.73 ? 134 ALA B CA 1 ATOM 2654 C C . ALA B 1 153 ? 17.806 8.900 -30.656 1.00 37.75 ? 134 ALA B C 1 ATOM 2655 O O . ALA B 1 153 ? 18.071 9.418 -29.566 1.00 40.94 ? 134 ALA B O 1 ATOM 2656 C CB . ALA B 1 153 ? 15.485 8.044 -30.984 1.00 32.40 ? 134 ALA B CB 1 ATOM 2657 N N . THR B 1 154 ? 18.276 9.371 -31.808 1.00 36.32 ? 135 THR B N 1 ATOM 2658 C CA . THR B 1 154 ? 18.951 10.667 -31.856 1.00 41.18 ? 135 THR B CA 1 ATOM 2659 C C . THR B 1 154 ? 18.200 11.654 -32.739 1.00 39.55 ? 135 THR B C 1 ATOM 2660 O O . THR B 1 154 ? 18.188 11.519 -33.958 1.00 44.86 ? 135 THR B O 1 ATOM 2661 C CB . THR B 1 154 ? 20.413 10.564 -32.311 1.00 37.39 ? 135 THR B CB 1 ATOM 2662 O OG1 . THR B 1 154 ? 21.064 9.533 -31.569 1.00 45.35 ? 135 THR B OG1 1 ATOM 2663 C CG2 . THR B 1 154 ? 21.140 11.874 -32.039 1.00 39.94 ? 135 THR B CG2 1 ATOM 2664 N N . CYS B 1 155 ? 17.568 12.632 -32.098 1.00 39.62 ? 136 CYS B N 1 ATOM 2665 C CA . CYS B 1 155 ? 16.827 13.682 -32.778 1.00 40.79 ? 136 CYS B CA 1 ATOM 2666 C C . CYS B 1 155 ? 17.687 14.957 -32.884 1.00 37.30 ? 136 CYS B C 1 ATOM 2667 O O . CYS B 1 155 ? 18.229 15.412 -31.873 1.00 38.49 ? 136 CYS B O 1 ATOM 2668 C CB . CYS B 1 155 ? 15.551 13.969 -31.983 1.00 41.12 ? 136 CYS B CB 1 ATOM 2669 S SG . CYS B 1 155 ? 14.476 15.236 -32.730 1.00 87.55 ? 136 CYS B SG 1 ATOM 2670 N N . ARG B 1 156 ? 17.831 15.519 -34.092 1.00 34.25 ? 137 ARG B N 1 ATOM 2671 C CA . ARG B 1 156 ? 18.569 16.785 -34.282 1.00 32.13 ? 137 ARG B CA 1 ATOM 2672 C C . ARG B 1 156 ? 17.635 17.993 -34.471 1.00 37.67 ? 137 ARG B C 1 ATOM 2673 O O . ARG B 1 156 ? 16.638 17.919 -35.195 1.00 40.21 ? 137 ARG B O 1 ATOM 2674 C CB . ARG B 1 156 ? 19.540 16.710 -35.467 1.00 34.85 ? 137 ARG B CB 1 ATOM 2675 C CG . ARG B 1 156 ? 20.311 15.392 -35.619 1.00 46.02 ? 137 ARG B CG 1 ATOM 2676 C CD . ARG B 1 156 ? 21.305 15.423 -36.817 1.00 54.01 ? 137 ARG B CD 1 ATOM 2677 N NE . ARG B 1 156 ? 20.827 16.172 -37.997 1.00 58.65 ? 137 ARG B NE 1 ATOM 2678 C CZ . ARG B 1 156 ? 20.140 15.647 -39.019 1.00 61.57 ? 137 ARG B CZ 1 ATOM 2679 N NH1 . ARG B 1 156 ? 19.819 14.358 -39.033 1.00 57.69 ? 137 ARG B NH1 1 ATOM 2680 N NH2 . ARG B 1 156 ? 19.763 16.417 -40.034 1.00 54.60 ? 137 ARG B NH2 1 ATOM 2681 N N . ILE B 1 157 ? 17.962 19.107 -33.821 1.00 38.71 ? 138 ILE B N 1 ATOM 2682 C CA . ILE B 1 157 ? 17.190 20.339 -33.985 1.00 32.44 ? 138 ILE B CA 1 ATOM 2683 C C . ILE B 1 157 ? 18.083 21.419 -34.552 1.00 29.64 ? 138 ILE B C 1 ATOM 2684 O O . ILE B 1 157 ? 19.138 21.714 -33.989 1.00 33.11 ? 138 ILE B O 1 ATOM 2685 C CB . ILE B 1 157 ? 16.625 20.829 -32.652 1.00 31.94 ? 138 ILE B CB 1 ATOM 2686 C CG1 . ILE B 1 157 ? 15.681 19.780 -32.065 1.00 30.61 ? 138 ILE B CG1 1 ATOM 2687 C CG2 . ILE B 1 157 ? 15.930 22.173 -32.824 1.00 26.96 ? 138 ILE B CG2 1 ATOM 2688 C CD1 . ILE B 1 157 ? 14.838 20.303 -30.936 1.00 28.02 ? 138 ILE B CD1 1 ATOM 2689 N N . LYS B 1 158 ? 17.670 22.003 -35.670 1.00 30.53 ? 139 LYS B N 1 ATOM 2690 C CA . LYS B 1 158 ? 18.497 22.992 -36.360 1.00 28.61 ? 139 LYS B CA 1 ATOM 2691 C C . LYS B 1 158 ? 17.937 24.406 -36.165 1.00 27.79 ? 139 LYS B C 1 ATOM 2692 O O . LYS B 1 158 ? 16.802 24.705 -36.556 1.00 30.54 ? 139 LYS B O 1 ATOM 2693 C CB . LYS B 1 158 ? 18.602 22.636 -37.845 1.00 28.89 ? 139 LYS B CB 1 ATOM 2694 C CG . LYS B 1 158 ? 19.297 23.679 -38.705 1.00 26.57 ? 139 LYS B CG 1 ATOM 2695 C CD . LYS B 1 158 ? 19.019 23.420 -40.187 1.00 32.20 ? 139 LYS B CD 1 ATOM 2696 C CE . LYS B 1 158 ? 19.363 24.628 -41.063 1.00 33.05 ? 139 LYS B CE 1 ATOM 2697 N NZ . LYS B 1 158 ? 19.282 24.342 -42.524 1.00 30.06 ? 139 LYS B NZ 1 ATOM 2698 N N . ILE B 1 159 ? 18.731 25.272 -35.543 1.00 26.19 ? 140 ILE B N 1 ATOM 2699 C CA . ILE B 1 159 ? 18.281 26.614 -35.193 1.00 20.89 ? 140 ILE B CA 1 ATOM 2700 C C . ILE B 1 159 ? 19.218 27.679 -35.754 1.00 26.32 ? 140 ILE B C 1 ATOM 2701 O O . ILE B 1 159 ? 20.435 27.600 -35.557 1.00 27.37 ? 140 ILE B O 1 ATOM 2702 C CB . ILE B 1 159 ? 18.229 26.779 -33.669 1.00 23.15 ? 140 ILE B CB 1 ATOM 2703 C CG1 . ILE B 1 159 ? 17.171 25.846 -33.073 1.00 24.44 ? 140 ILE B CG1 1 ATOM 2704 C CG2 . ILE B 1 159 ? 17.944 28.231 -33.293 1.00 23.69 ? 140 ILE B CG2 1 ATOM 2705 C CD1 . ILE B 1 159 ? 16.994 26.001 -31.570 1.00 26.63 ? 140 ILE B CD1 1 ATOM 2706 N N . GLY B 1 160 ? 18.664 28.679 -36.443 1.00 27.51 ? 141 GLY B N 1 ATOM 2707 C CA . GLY B 1 160 ? 19.480 29.750 -36.992 1.00 23.17 ? 141 GLY B CA 1 ATOM 2708 C C . GLY B 1 160 ? 18.708 31.007 -37.335 1.00 23.76 ? 141 GLY B C 1 ATOM 2709 O O . GLY B 1 160 ? 17.480 31.045 -37.207 1.00 22.62 ? 141 GLY B O 1 ATOM 2710 N N . SER B 1 161 ? 19.422 32.045 -37.772 1.00 26.38 ? 142 SER B N 1 ATOM 2711 C CA . SER B 1 161 ? 18.765 33.274 -38.225 1.00 21.56 ? 142 SER B CA 1 ATOM 2712 C C . SER B 1 161 ? 17.990 33.042 -39.509 1.00 18.83 ? 142 SER B C 1 ATOM 2713 O O . SER B 1 161 ? 18.489 32.411 -40.429 1.00 19.11 ? 142 SER B O 1 ATOM 2714 C CB . SER B 1 161 ? 19.784 34.369 -38.479 1.00 21.99 ? 142 SER B CB 1 ATOM 2715 O OG . SER B 1 161 ? 19.131 35.509 -39.016 1.00 24.96 ? 142 SER B OG 1 ATOM 2716 N N . TRP B 1 162 ? 16.774 33.567 -39.576 1.00 22.05 ? 143 TRP B N 1 ATOM 2717 C CA . TRP B 1 162 ? 15.927 33.332 -40.734 1.00 18.70 ? 143 TRP B CA 1 ATOM 2718 C C . TRP B 1 162 ? 16.255 34.254 -41.912 1.00 21.26 ? 143 TRP B C 1 ATOM 2719 O O . TRP B 1 162 ? 16.160 33.835 -43.067 1.00 23.28 ? 143 TRP B O 1 ATOM 2720 C CB . TRP B 1 162 ? 14.446 33.438 -40.356 1.00 18.04 ? 143 TRP B CB 1 ATOM 2721 C CG . TRP B 1 162 ? 13.529 32.838 -41.397 1.00 19.08 ? 143 TRP B CG 1 ATOM 2722 C CD1 . TRP B 1 162 ? 12.715 33.515 -42.274 1.00 22.84 ? 143 TRP B CD1 1 ATOM 2723 C CD2 . TRP B 1 162 ? 13.358 31.446 -41.680 1.00 20.27 ? 143 TRP B CD2 1 ATOM 2724 N NE1 . TRP B 1 162 ? 12.039 32.624 -43.079 1.00 24.19 ? 143 TRP B NE1 1 ATOM 2725 C CE2 . TRP B 1 162 ? 12.413 31.350 -42.738 1.00 26.58 ? 143 TRP B CE2 1 ATOM 2726 C CE3 . TRP B 1 162 ? 13.903 30.268 -41.149 1.00 22.86 ? 143 TRP B CE3 1 ATOM 2727 C CZ2 . TRP B 1 162 ? 12.006 30.106 -43.267 1.00 23.16 ? 143 TRP B CZ2 1 ATOM 2728 C CZ3 . TRP B 1 162 ? 13.495 29.042 -41.667 1.00 22.57 ? 143 TRP B CZ3 1 ATOM 2729 C CH2 . TRP B 1 162 ? 12.556 28.973 -42.723 1.00 21.26 ? 143 TRP B CH2 1 ATOM 2730 N N . THR B 1 163 ? 16.637 35.499 -41.627 1.00 21.71 ? 144 THR B N 1 ATOM 2731 C CA . THR B 1 163 ? 16.812 36.501 -42.687 1.00 23.01 ? 144 THR B CA 1 ATOM 2732 C C . THR B 1 163 ? 18.179 37.151 -42.714 1.00 25.23 ? 144 THR B C 1 ATOM 2733 O O . THR B 1 163 ? 18.476 37.882 -43.648 1.00 34.22 ? 144 THR B O 1 ATOM 2734 C CB . THR B 1 163 ? 15.765 37.658 -42.617 1.00 26.51 ? 144 THR B CB 1 ATOM 2735 O OG1 . THR B 1 163 ? 15.961 38.425 -41.416 1.00 27.88 ? 144 THR B OG1 1 ATOM 2736 C CG2 . THR B 1 163 ? 14.334 37.143 -42.680 1.00 20.09 ? 144 THR B CG2 1 ATOM 2737 N N . HIS B 1 164 ? 18.994 36.925 -41.690 1.00 26.28 ? 145 HIS B N 1 ATOM 2738 C CA . HIS B 1 164 ? 20.326 37.538 -41.649 1.00 30.33 ? 145 HIS B CA 1 ATOM 2739 C C . HIS B 1 164 ? 21.455 36.550 -41.972 1.00 28.82 ? 145 HIS B C 1 ATOM 2740 O O . HIS B 1 164 ? 21.550 35.487 -41.359 1.00 28.53 ? 145 HIS B O 1 ATOM 2741 C CB . HIS B 1 164 ? 20.566 38.181 -40.281 1.00 28.47 ? 145 HIS B CB 1 ATOM 2742 C CG . HIS B 1 164 ? 19.688 39.359 -40.008 1.00 28.98 ? 145 HIS B CG 1 ATOM 2743 N ND1 . HIS B 1 164 ? 19.841 40.564 -40.655 1.00 31.77 ? 145 HIS B ND1 1 ATOM 2744 C CD2 . HIS B 1 164 ? 18.653 39.517 -39.150 1.00 28.32 ? 145 HIS B CD2 1 ATOM 2745 C CE1 . HIS B 1 164 ? 18.939 41.421 -40.207 1.00 29.86 ? 145 HIS B CE1 1 ATOM 2746 N NE2 . HIS B 1 164 ? 18.204 40.806 -39.297 1.00 35.89 ? 145 HIS B NE2 1 ATOM 2747 N N . HIS B 1 165 ? 22.321 36.901 -42.919 1.00 29.49 ? 146 HIS B N 1 ATOM 2748 C CA . HIS B 1 165 ? 23.427 36.003 -43.276 1.00 33.12 ? 146 HIS B CA 1 ATOM 2749 C C . HIS B 1 165 ? 24.622 36.078 -42.307 1.00 31.39 ? 146 HIS B C 1 ATOM 2750 O O . HIS B 1 165 ? 24.577 36.790 -41.308 1.00 34.53 ? 146 HIS B O 1 ATOM 2751 C CB . HIS B 1 165 ? 23.851 36.194 -44.742 1.00 38.14 ? 146 HIS B CB 1 ATOM 2752 C CG . HIS B 1 165 ? 24.325 37.579 -45.066 1.00 38.07 ? 146 HIS B CG 1 ATOM 2753 N ND1 . HIS B 1 165 ? 25.452 38.127 -44.497 1.00 40.85 ? 146 HIS B ND1 1 ATOM 2754 C CD2 . HIS B 1 165 ? 23.822 38.509 -45.909 1.00 40.93 ? 146 HIS B CD2 1 ATOM 2755 C CE1 . HIS B 1 165 ? 25.620 39.355 -44.971 1.00 48.82 ? 146 HIS B CE1 1 ATOM 2756 N NE2 . HIS B 1 165 ? 24.651 39.609 -45.827 1.00 49.18 ? 146 HIS B NE2 1 ATOM 2757 N N . SER B 1 166 ? 25.688 35.349 -42.619 1.00 32.82 ? 147 SER B N 1 ATOM 2758 C CA . SER B 1 166 ? 26.807 35.146 -41.688 1.00 35.83 ? 147 SER B CA 1 ATOM 2759 C C . SER B 1 166 ? 27.612 36.390 -41.322 1.00 37.89 ? 147 SER B C 1 ATOM 2760 O O . SER B 1 166 ? 28.344 36.375 -40.330 1.00 38.04 ? 147 SER B O 1 ATOM 2761 C CB . SER B 1 166 ? 27.765 34.094 -42.240 1.00 33.44 ? 147 SER B CB 1 ATOM 2762 O OG . SER B 1 166 ? 28.352 34.559 -43.442 1.00 39.84 ? 147 SER B OG 1 ATOM 2763 N N . ARG B 1 167 ? 27.505 37.447 -42.128 1.00 41.19 ? 148 ARG B N 1 ATOM 2764 C CA . ARG B 1 167 ? 28.243 38.682 -41.855 1.00 44.38 ? 148 ARG B CA 1 ATOM 2765 C C . ARG B 1 167 ? 27.426 39.663 -41.014 1.00 40.52 ? 148 ARG B C 1 ATOM 2766 O O . ARG B 1 167 ? 27.940 40.697 -40.564 1.00 36.06 ? 148 ARG B O 1 ATOM 2767 C CB . ARG B 1 167 ? 28.693 39.358 -43.152 1.00 55.38 ? 148 ARG B CB 1 ATOM 2768 C CG . ARG B 1 167 ? 29.744 38.587 -43.965 1.00 63.62 ? 148 ARG B CG 1 ATOM 2769 C CD . ARG B 1 167 ? 30.206 39.399 -45.194 1.00 70.34 ? 148 ARG B CD 1 ATOM 2770 N NE . ARG B 1 167 ? 29.304 40.510 -45.515 1.00 77.69 ? 148 ARG B NE 1 ATOM 2771 C CZ . ARG B 1 167 ? 28.881 40.825 -46.741 1.00 81.06 ? 148 ARG B CZ 1 ATOM 2772 N NH1 . ARG B 1 167 ? 29.274 40.111 -47.792 1.00 73.34 ? 148 ARG B NH1 1 ATOM 2773 N NH2 . ARG B 1 167 ? 28.057 41.861 -46.917 1.00 83.09 ? 148 ARG B NH2 1 ATOM 2774 N N . GLU B 1 168 ? 26.154 39.325 -40.812 1.00 39.33 ? 149 GLU B N 1 ATOM 2775 C CA . GLU B 1 168 ? 25.246 40.132 -39.997 1.00 38.99 ? 149 GLU B CA 1 ATOM 2776 C C . GLU B 1 168 ? 24.962 39.485 -38.633 1.00 35.56 ? 149 GLU B C 1 ATOM 2777 O O . GLU B 1 168 ? 25.048 40.146 -37.588 1.00 34.49 ? 149 GLU B O 1 ATOM 2778 C CB . GLU B 1 168 ? 23.945 40.412 -40.767 1.00 35.27 ? 149 GLU B CB 1 ATOM 2779 C CG . GLU B 1 168 ? 24.132 41.293 -42.008 1.00 36.60 ? 149 GLU B CG 1 ATOM 2780 C CD . GLU B 1 168 ? 22.865 41.460 -42.855 1.00 43.87 ? 149 GLU B CD 1 ATOM 2781 O OE1 . GLU B 1 168 ? 22.058 40.502 -42.935 1.00 45.21 ? 149 GLU B OE1 1 ATOM 2782 O OE2 . GLU B 1 168 ? 22.678 42.554 -43.446 1.00 54.67 ? 149 GLU B OE2 1 ATOM 2783 N N . ILE B 1 169 ? 24.624 38.197 -38.657 1.00 28.12 ? 150 ILE B N 1 ATOM 2784 C CA . ILE B 1 169 ? 24.471 37.408 -37.437 1.00 30.76 ? 150 ILE B CA 1 ATOM 2785 C C . ILE B 1 169 ? 25.278 36.105 -37.513 1.00 34.89 ? 150 ILE B C 1 ATOM 2786 O O . ILE B 1 169 ? 25.149 35.335 -38.479 1.00 29.94 ? 150 ILE B O 1 ATOM 2787 C CB . ILE B 1 169 ? 22.985 37.054 -37.159 1.00 31.51 ? 150 ILE B CB 1 ATOM 2788 C CG1 . ILE B 1 169 ? 22.202 38.295 -36.732 1.00 29.96 ? 150 ILE B CG1 1 ATOM 2789 C CG2 . ILE B 1 169 ? 22.872 35.973 -36.087 1.00 26.42 ? 150 ILE B CG2 1 ATOM 2790 C CD1 . ILE B 1 169 ? 20.738 38.030 -36.408 1.00 21.02 ? 150 ILE B CD1 1 ATOM 2791 N N . SER B 1 170 ? 26.110 35.869 -36.500 1.00 31.70 ? 151 SER B N 1 ATOM 2792 C CA . SER B 1 170 ? 26.729 34.563 -36.315 1.00 33.83 ? 151 SER B CA 1 ATOM 2793 C C . SER B 1 170 ? 26.168 33.858 -35.068 1.00 36.00 ? 151 SER B C 1 ATOM 2794 O O . SER B 1 170 ? 26.071 34.469 -33.991 1.00 33.26 ? 151 SER B O 1 ATOM 2795 C CB . SER B 1 170 ? 28.245 34.702 -36.212 1.00 35.10 ? 151 SER B CB 1 ATOM 2796 O OG . SER B 1 170 ? 28.611 35.367 -35.019 1.00 33.54 ? 151 SER B OG 1 ATOM 2797 N N . VAL B 1 171 ? 25.794 32.585 -35.214 1.00 33.33 ? 152 VAL B N 1 ATOM 2798 C CA . VAL B 1 171 ? 25.307 31.786 -34.084 1.00 33.86 ? 152 VAL B CA 1 ATOM 2799 C C . VAL B 1 171 ? 26.359 30.772 -33.660 1.00 34.79 ? 152 VAL B C 1 ATOM 2800 O O . VAL B 1 171 ? 26.978 30.129 -34.494 1.00 43.49 ? 152 VAL B O 1 ATOM 2801 C CB . VAL B 1 171 ? 23.995 31.031 -34.411 1.00 30.57 ? 152 VAL B CB 1 ATOM 2802 C CG1 . VAL B 1 171 ? 22.794 31.945 -34.303 1.00 27.95 ? 152 VAL B CG1 1 ATOM 2803 C CG2 . VAL B 1 171 ? 24.067 30.437 -35.785 1.00 31.37 ? 152 VAL B CG2 1 ATOM 2804 N N . ASP B 1 172 ? 26.553 30.629 -32.356 1.00 36.81 ? 153 ASP B N 1 ATOM 2805 C CA . ASP B 1 172 ? 27.584 29.752 -31.819 1.00 36.05 ? 153 ASP B CA 1 ATOM 2806 C C . ASP B 1 172 ? 27.052 29.047 -30.590 1.00 42.54 ? 153 ASP B C 1 ATOM 2807 O O . ASP B 1 172 ? 26.267 29.626 -29.832 1.00 38.54 ? 153 ASP B O 1 ATOM 2808 C CB . ASP B 1 172 ? 28.817 30.565 -31.427 1.00 40.72 ? 153 ASP B CB 1 ATOM 2809 C CG . ASP B 1 172 ? 29.142 31.690 -32.443 1.00 61.31 ? 153 ASP B CG 1 ATOM 2810 O OD1 . ASP B 1 172 ? 29.738 31.389 -33.518 1.00 56.59 ? 153 ASP B OD1 1 ATOM 2811 O OD2 . ASP B 1 172 ? 28.807 32.877 -32.159 1.00 50.13 ? 153 ASP B OD2 1 ATOM 2812 N N . PRO B 1 173 ? 27.453 27.782 -30.396 1.00 44.82 ? 154 PRO B N 1 ATOM 2813 C CA . PRO B 1 173 ? 27.049 27.040 -29.197 1.00 46.55 ? 154 PRO B CA 1 ATOM 2814 C C . PRO B 1 173 ? 27.792 27.595 -27.983 1.00 47.41 ? 154 PRO B C 1 ATOM 2815 O O . PRO B 1 173 ? 28.850 28.202 -28.134 1.00 46.74 ? 154 PRO B O 1 ATOM 2816 C CB . PRO B 1 173 ? 27.504 25.610 -29.499 1.00 40.10 ? 154 PRO B CB 1 ATOM 2817 C CG . PRO B 1 173 ? 27.680 25.572 -30.982 1.00 41.44 ? 154 PRO B CG 1 ATOM 2818 C CD . PRO B 1 173 ? 28.180 26.932 -31.346 1.00 39.65 ? 154 PRO B CD 1 ATOM 2819 N N . THR B 1 174 ? 27.245 27.385 -26.795 1.00 46.38 ? 155 THR B N 1 ATOM 2820 C CA . THR B 1 174 ? 27.841 27.927 -25.580 1.00 49.27 ? 155 THR B CA 1 ATOM 2821 C C . THR B 1 174 ? 29.035 27.103 -25.088 1.00 52.43 ? 155 THR B C 1 ATOM 2822 O O . THR B 1 174 ? 28.996 25.870 -25.071 1.00 58.95 ? 155 THR B O 1 ATOM 2823 C CB . THR B 1 174 ? 26.784 28.049 -24.465 1.00 51.92 ? 155 THR B CB 1 ATOM 2824 O OG1 . THR B 1 174 ? 25.843 29.074 -24.818 1.00 49.88 ? 155 THR B OG1 1 ATOM 2825 C CG2 . THR B 1 174 ? 27.435 28.394 -23.136 1.00 56.96 ? 155 THR B CG2 1 ATOM 2826 N N . ASP B 1 180 ? 23.122 18.237 -19.028 1.00 64.09 ? 161 ASP B N 1 ATOM 2827 C CA . ASP B 1 180 ? 22.145 17.647 -19.947 1.00 65.47 ? 161 ASP B CA 1 ATOM 2828 C C . ASP B 1 180 ? 20.767 17.522 -19.296 1.00 59.01 ? 161 ASP B C 1 ATOM 2829 O O . ASP B 1 180 ? 19.806 18.209 -19.665 1.00 55.24 ? 161 ASP B O 1 ATOM 2830 C CB . ASP B 1 180 ? 22.568 16.235 -20.382 1.00 67.70 ? 161 ASP B CB 1 ATOM 2831 C CG . ASP B 1 180 ? 23.977 16.166 -20.967 1.00 70.48 ? 161 ASP B CG 1 ATOM 2832 O OD1 . ASP B 1 180 ? 24.423 17.139 -21.616 1.00 70.02 ? 161 ASP B OD1 1 ATOM 2833 O OD2 . ASP B 1 180 ? 24.626 15.102 -20.781 1.00 70.78 ? 161 ASP B OD2 1 ATOM 2834 N N . SER B 1 181 ? 20.701 16.603 -18.337 1.00 56.92 ? 162 SER B N 1 ATOM 2835 C CA . SER B 1 181 ? 19.511 16.293 -17.550 1.00 60.88 ? 162 SER B CA 1 ATOM 2836 C C . SER B 1 181 ? 19.370 17.230 -16.354 1.00 51.98 ? 162 SER B C 1 ATOM 2837 O O . SER B 1 181 ? 18.573 16.965 -15.443 1.00 51.79 ? 162 SER B O 1 ATOM 2838 C CB . SER B 1 181 ? 19.594 14.844 -17.026 1.00 65.55 ? 162 SER B CB 1 ATOM 2839 O OG . SER B 1 181 ? 19.319 13.876 -18.036 1.00 61.06 ? 162 SER B OG 1 ATOM 2840 N N . GLU B 1 182 ? 20.149 18.309 -16.353 1.00 44.76 ? 163 GLU B N 1 ATOM 2841 C CA . GLU B 1 182 ? 20.243 19.166 -15.179 1.00 50.22 ? 163 GLU B CA 1 ATOM 2842 C C . GLU B 1 182 ? 18.876 19.693 -14.721 1.00 46.28 ? 163 GLU B C 1 ATOM 2843 O O . GLU B 1 182 ? 18.588 19.746 -13.527 1.00 50.18 ? 163 GLU B O 1 ATOM 2844 C CB . GLU B 1 182 ? 21.229 20.315 -15.416 1.00 53.24 ? 163 GLU B CB 1 ATOM 2845 C CG . GLU B 1 182 ? 21.569 21.071 -14.137 1.00 50.30 ? 163 GLU B CG 1 ATOM 2846 C CD . GLU B 1 182 ? 22.444 22.277 -14.384 1.00 69.17 ? 163 GLU B CD 1 ATOM 2847 O OE1 . GLU B 1 182 ? 22.876 22.477 -15.546 1.00 85.84 ? 163 GLU B OE1 1 ATOM 2848 O OE2 . GLU B 1 182 ? 22.696 23.027 -13.413 1.00 77.87 ? 163 GLU B OE2 1 ATOM 2849 N N . TYR B 1 183 ? 18.031 20.061 -15.676 1.00 40.11 ? 164 TYR B N 1 ATOM 2850 C CA . TYR B 1 183 ? 16.697 20.534 -15.358 1.00 28.98 ? 164 TYR B CA 1 ATOM 2851 C C . TYR B 1 183 ? 15.633 19.629 -15.972 1.00 32.93 ? 164 TYR B C 1 ATOM 2852 O O . TYR B 1 183 ? 14.456 19.995 -16.016 1.00 31.57 ? 164 TYR B O 1 ATOM 2853 C CB . TYR B 1 183 ? 16.502 21.940 -15.903 1.00 40.26 ? 164 TYR B CB 1 ATOM 2854 C CG . TYR B 1 183 ? 17.578 22.920 -15.512 1.00 51.59 ? 164 TYR B CG 1 ATOM 2855 C CD1 . TYR B 1 183 ? 17.794 23.239 -14.175 1.00 50.98 ? 164 TYR B CD1 1 ATOM 2856 C CD2 . TYR B 1 183 ? 18.367 23.545 -16.482 1.00 47.83 ? 164 TYR B CD2 1 ATOM 2857 C CE1 . TYR B 1 183 ? 18.771 24.140 -13.808 1.00 55.10 ? 164 TYR B CE1 1 ATOM 2858 C CE2 . TYR B 1 183 ? 19.351 24.445 -16.130 1.00 49.81 ? 164 TYR B CE2 1 ATOM 2859 C CZ . TYR B 1 183 ? 19.549 24.745 -14.788 1.00 64.78 ? 164 TYR B CZ 1 ATOM 2860 O OH . TYR B 1 183 ? 20.530 25.651 -14.425 1.00 73.97 ? 164 TYR B OH 1 ATOM 2861 N N . PHE B 1 184 ? 16.046 18.462 -16.463 1.00 31.44 ? 165 PHE B N 1 ATOM 2862 C CA . PHE B 1 184 ? 15.110 17.516 -17.062 1.00 31.02 ? 165 PHE B CA 1 ATOM 2863 C C . PHE B 1 184 ? 14.184 16.896 -16.025 1.00 36.31 ? 165 PHE B C 1 ATOM 2864 O O . PHE B 1 184 ? 14.610 16.554 -14.916 1.00 39.15 ? 165 PHE B O 1 ATOM 2865 C CB . PHE B 1 184 ? 15.826 16.405 -17.829 1.00 29.87 ? 165 PHE B CB 1 ATOM 2866 C CG . PHE B 1 184 ? 14.926 15.665 -18.768 1.00 22.70 ? 165 PHE B CG 1 ATOM 2867 C CD1 . PHE B 1 184 ? 14.401 16.299 -19.891 1.00 24.03 ? 165 PHE B CD1 1 ATOM 2868 C CD2 . PHE B 1 184 ? 14.597 14.346 -18.534 1.00 26.16 ? 165 PHE B CD2 1 ATOM 2869 C CE1 . PHE B 1 184 ? 13.556 15.618 -20.776 1.00 26.14 ? 165 PHE B CE1 1 ATOM 2870 C CE2 . PHE B 1 184 ? 13.751 13.643 -19.413 1.00 31.23 ? 165 PHE B CE2 1 ATOM 2871 C CZ . PHE B 1 184 ? 13.225 14.287 -20.535 1.00 29.81 ? 165 PHE B CZ 1 ATOM 2872 N N . SER B 1 185 ? 12.913 16.751 -16.391 1.00 31.96 ? 166 SER B N 1 ATOM 2873 C CA . SER B 1 185 ? 11.910 16.253 -15.467 1.00 27.00 ? 166 SER B CA 1 ATOM 2874 C C . SER B 1 185 ? 12.120 14.767 -15.153 1.00 34.80 ? 166 SER B C 1 ATOM 2875 O O . SER B 1 185 ? 12.259 13.935 -16.057 1.00 38.83 ? 166 SER B O 1 ATOM 2876 C CB . SER B 1 185 ? 10.516 16.479 -16.050 1.00 29.63 ? 166 SER B CB 1 ATOM 2877 O OG . SER B 1 185 ? 9.504 16.141 -15.111 1.00 30.79 ? 166 SER B OG 1 ATOM 2878 N N . GLN B 1 186 ? 12.138 14.437 -13.864 1.00 42.51 ? 167 GLN B N 1 ATOM 2879 C CA . GLN B 1 186 ? 12.192 13.040 -13.422 1.00 37.99 ? 167 GLN B CA 1 ATOM 2880 C C . GLN B 1 186 ? 10.895 12.312 -13.752 1.00 36.89 ? 167 GLN B C 1 ATOM 2881 O O . GLN B 1 186 ? 10.877 11.088 -13.807 1.00 44.91 ? 167 GLN B O 1 ATOM 2882 C CB . GLN B 1 186 ? 12.461 12.959 -11.919 1.00 35.05 ? 167 GLN B CB 1 ATOM 2883 C CG . GLN B 1 186 ? 11.725 14.041 -11.130 1.00 47.33 ? 167 GLN B CG 1 ATOM 2884 C CD . GLN B 1 186 ? 11.851 13.908 -9.612 1.00 54.15 ? 167 GLN B CD 1 ATOM 2885 O OE1 . GLN B 1 186 ? 11.944 12.797 -9.073 1.00 41.75 ? 167 GLN B OE1 1 ATOM 2886 N NE2 . GLN B 1 186 ? 11.838 15.055 -8.911 1.00 58.08 ? 167 GLN B NE2 1 ATOM 2887 N N . TYR B 1 187 ? 9.820 13.063 -13.988 1.00 31.54 ? 168 TYR B N 1 ATOM 2888 C CA . TYR B 1 187 ? 8.512 12.459 -14.228 1.00 32.72 ? 168 TYR B CA 1 ATOM 2889 C C . TYR B 1 187 ? 8.183 12.195 -15.706 1.00 35.87 ? 168 TYR B C 1 ATOM 2890 O O . TYR B 1 187 ? 7.166 11.569 -16.020 1.00 40.47 ? 168 TYR B O 1 ATOM 2891 C CB . TYR B 1 187 ? 7.398 13.246 -13.531 1.00 28.98 ? 168 TYR B CB 1 ATOM 2892 C CG . TYR B 1 187 ? 7.659 13.426 -12.051 1.00 37.32 ? 168 TYR B CG 1 ATOM 2893 C CD1 . TYR B 1 187 ? 7.760 12.332 -11.200 1.00 42.14 ? 168 TYR B CD1 1 ATOM 2894 C CD2 . TYR B 1 187 ? 7.814 14.683 -11.503 1.00 39.06 ? 168 TYR B CD2 1 ATOM 2895 C CE1 . TYR B 1 187 ? 8.004 12.489 -9.841 1.00 39.40 ? 168 TYR B CE1 1 ATOM 2896 C CE2 . TYR B 1 187 ? 8.070 14.848 -10.142 1.00 48.26 ? 168 TYR B CE2 1 ATOM 2897 C CZ . TYR B 1 187 ? 8.159 13.743 -9.319 1.00 39.71 ? 168 TYR B CZ 1 ATOM 2898 O OH . TYR B 1 187 ? 8.405 13.891 -7.974 1.00 42.61 ? 168 TYR B OH 1 ATOM 2899 N N . SER B 1 188 ? 9.047 12.635 -16.612 1.00 27.93 ? 169 SER B N 1 ATOM 2900 C CA . SER B 1 188 ? 8.909 12.249 -18.018 1.00 28.53 ? 169 SER B CA 1 ATOM 2901 C C . SER B 1 188 ? 8.945 10.720 -18.202 1.00 35.78 ? 169 SER B C 1 ATOM 2902 O O . SER B 1 188 ? 9.547 10.007 -17.384 1.00 38.89 ? 169 SER B O 1 ATOM 2903 C CB . SER B 1 188 ? 10.026 12.882 -18.849 1.00 27.66 ? 169 SER B CB 1 ATOM 2904 O OG . SER B 1 188 ? 9.826 12.642 -20.227 1.00 25.56 ? 169 SER B OG 1 ATOM 2905 N N . ARG B 1 189 ? 8.318 10.222 -19.275 1.00 32.89 ? 170 ARG B N 1 ATOM 2906 C CA . ARG B 1 189 ? 8.401 8.796 -19.629 1.00 30.56 ? 170 ARG B CA 1 ATOM 2907 C C . ARG B 1 189 ? 9.723 8.473 -20.307 1.00 30.28 ? 170 ARG B C 1 ATOM 2908 O O . ARG B 1 189 ? 9.965 7.324 -20.672 1.00 28.54 ? 170 ARG B O 1 ATOM 2909 C CB . ARG B 1 189 ? 7.267 8.365 -20.574 1.00 30.72 ? 170 ARG B CB 1 ATOM 2910 C CG . ARG B 1 189 ? 5.874 8.488 -20.004 1.00 26.64 ? 170 ARG B CG 1 ATOM 2911 C CD . ARG B 1 189 ? 5.027 7.312 -20.412 1.00 34.32 ? 170 ARG B CD 1 ATOM 2912 N NE . ARG B 1 189 ? 4.823 7.218 -21.857 1.00 49.24 ? 170 ARG B NE 1 ATOM 2913 C CZ . ARG B 1 189 ? 4.466 6.098 -22.496 1.00 62.14 ? 170 ARG B CZ 1 ATOM 2914 N NH1 . ARG B 1 189 ? 4.292 4.960 -21.828 1.00 52.96 ? 170 ARG B NH1 1 ATOM 2915 N NH2 . ARG B 1 189 ? 4.296 6.109 -23.812 1.00 66.35 ? 170 ARG B NH2 1 ATOM 2916 N N . PHE B 1 190 ? 10.561 9.493 -20.490 1.00 29.84 ? 171 PHE B N 1 ATOM 2917 C CA . PHE B 1 190 ? 11.815 9.333 -21.219 1.00 27.01 ? 171 PHE B CA 1 ATOM 2918 C C . PHE B 1 190 ? 12.984 9.845 -20.405 1.00 33.77 ? 171 PHE B C 1 ATOM 2919 O O . PHE B 1 190 ? 12.798 10.533 -19.391 1.00 37.60 ? 171 PHE B O 1 ATOM 2920 C CB . PHE B 1 190 ? 11.765 10.069 -22.564 1.00 29.02 ? 171 PHE B CB 1 ATOM 2921 C CG . PHE B 1 190 ? 10.577 9.702 -23.416 1.00 29.49 ? 171 PHE B CG 1 ATOM 2922 C CD1 . PHE B 1 190 ? 9.346 10.314 -23.214 1.00 24.33 ? 171 PHE B CD1 1 ATOM 2923 C CD2 . PHE B 1 190 ? 10.694 8.745 -24.427 1.00 32.23 ? 171 PHE B CD2 1 ATOM 2924 C CE1 . PHE B 1 190 ? 8.244 9.975 -23.997 1.00 31.67 ? 171 PHE B CE1 1 ATOM 2925 C CE2 . PHE B 1 190 ? 9.594 8.391 -25.220 1.00 31.77 ? 171 PHE B CE2 1 ATOM 2926 C CZ . PHE B 1 190 ? 8.367 9.008 -25.003 1.00 34.80 ? 171 PHE B CZ 1 ATOM 2927 N N . GLU B 1 191 ? 14.191 9.508 -20.856 1.00 35.94 ? 172 GLU B N 1 ATOM 2928 C CA . GLU B 1 191 ? 15.404 9.976 -20.196 1.00 31.04 ? 172 GLU B CA 1 ATOM 2929 C C . GLU B 1 191 ? 16.444 10.378 -21.231 1.00 33.52 ? 172 GLU B C 1 ATOM 2930 O O . GLU B 1 191 ? 16.450 9.860 -22.362 1.00 29.84 ? 172 GLU B O 1 ATOM 2931 C CB . GLU B 1 191 ? 15.944 8.923 -19.212 1.00 35.04 ? 172 GLU B CB 1 ATOM 2932 C CG . GLU B 1 191 ? 16.341 7.577 -19.828 1.00 42.10 ? 172 GLU B CG 1 ATOM 2933 C CD . GLU B 1 191 ? 16.706 6.538 -18.762 1.00 54.90 ? 172 GLU B CD 1 ATOM 2934 O OE1 . GLU B 1 191 ? 16.850 6.937 -17.583 1.00 51.52 ? 172 GLU B OE1 1 ATOM 2935 O OE2 . GLU B 1 191 ? 16.834 5.326 -19.096 1.00 61.27 ? 172 GLU B OE2 1 ATOM 2936 N N . ILE B 1 192 ? 17.313 11.312 -20.847 1.00 34.42 ? 173 ILE B N 1 ATOM 2937 C CA . ILE B 1 192 ? 18.331 11.822 -21.765 1.00 34.00 ? 173 ILE B CA 1 ATOM 2938 C C . ILE B 1 192 ? 19.627 11.051 -21.574 1.00 33.18 ? 173 ILE B C 1 ATOM 2939 O O . ILE B 1 192 ? 20.096 10.884 -20.452 1.00 32.80 ? 173 ILE B O 1 ATOM 2940 C CB . ILE B 1 192 ? 18.543 13.358 -21.604 1.00 31.15 ? 173 ILE B CB 1 ATOM 2941 C CG1 . ILE B 1 192 ? 17.229 14.091 -21.879 1.00 29.05 ? 173 ILE B CG1 1 ATOM 2942 C CG2 . ILE B 1 192 ? 19.653 13.875 -22.520 1.00 28.55 ? 173 ILE B CG2 1 ATOM 2943 C CD1 . ILE B 1 192 ? 17.318 15.571 -21.701 1.00 36.75 ? 173 ILE B CD1 1 ATOM 2944 N N . LEU B 1 193 ? 20.183 10.562 -22.678 1.00 34.82 ? 174 LEU B N 1 ATOM 2945 C CA . LEU B 1 193 ? 21.451 9.838 -22.648 1.00 38.76 ? 174 LEU B CA 1 ATOM 2946 C C . LEU B 1 193 ? 22.622 10.771 -22.933 1.00 40.65 ? 174 LEU B C 1 ATOM 2947 O O . LEU B 1 193 ? 23.672 10.671 -22.296 1.00 43.93 ? 174 LEU B O 1 ATOM 2948 C CB . LEU B 1 193 ? 21.435 8.692 -23.656 1.00 41.12 ? 174 LEU B CB 1 ATOM 2949 C CG . LEU B 1 193 ? 20.247 7.746 -23.489 1.00 41.30 ? 174 LEU B CG 1 ATOM 2950 C CD1 . LEU B 1 193 ? 20.236 6.655 -24.562 1.00 36.48 ? 174 LEU B CD1 1 ATOM 2951 C CD2 . LEU B 1 193 ? 20.220 7.157 -22.080 1.00 34.19 ? 174 LEU B CD2 1 ATOM 2952 N N . ASP B 1 194 ? 22.432 11.685 -23.884 1.00 41.61 ? 175 ASP B N 1 ATOM 2953 C CA . ASP B 1 194 ? 23.462 12.673 -24.217 1.00 42.51 ? 175 ASP B CA 1 ATOM 2954 C C . ASP B 1 194 ? 22.943 13.844 -25.065 1.00 42.86 ? 175 ASP B C 1 ATOM 2955 O O . ASP B 1 194 ? 21.982 13.701 -25.839 1.00 39.42 ? 175 ASP B O 1 ATOM 2956 C CB . ASP B 1 194 ? 24.625 11.991 -24.949 1.00 44.92 ? 175 ASP B CB 1 ATOM 2957 C CG . ASP B 1 194 ? 25.908 12.793 -24.875 1.00 57.41 ? 175 ASP B CG 1 ATOM 2958 O OD1 . ASP B 1 194 ? 26.145 13.424 -23.820 1.00 71.40 ? 175 ASP B OD1 1 ATOM 2959 O OD2 . ASP B 1 194 ? 26.671 12.800 -25.871 1.00 56.43 ? 175 ASP B OD2 1 ATOM 2960 N N . VAL B 1 195 ? 23.587 15.000 -24.918 1.00 40.99 ? 176 VAL B N 1 ATOM 2961 C CA . VAL B 1 195 ? 23.285 16.154 -25.762 1.00 41.02 ? 176 VAL B CA 1 ATOM 2962 C C . VAL B 1 195 ? 24.564 16.726 -26.361 1.00 40.27 ? 176 VAL B C 1 ATOM 2963 O O . VAL B 1 195 ? 25.459 17.135 -25.627 1.00 45.93 ? 176 VAL B O 1 ATOM 2964 C CB . VAL B 1 195 ? 22.563 17.281 -24.976 1.00 40.76 ? 176 VAL B CB 1 ATOM 2965 C CG1 . VAL B 1 195 ? 22.334 18.490 -25.871 1.00 38.29 ? 176 VAL B CG1 1 ATOM 2966 C CG2 . VAL B 1 195 ? 21.248 16.790 -24.398 1.00 41.16 ? 176 VAL B CG2 1 ATOM 2967 N N . THR B 1 196 ? 24.651 16.756 -27.688 1.00 37.76 ? 177 THR B N 1 ATOM 2968 C CA . THR B 1 196 ? 25.793 17.375 -28.363 1.00 40.61 ? 177 THR B CA 1 ATOM 2969 C C . THR B 1 196 ? 25.377 18.553 -29.250 1.00 44.49 ? 177 THR B C 1 ATOM 2970 O O . THR B 1 196 ? 24.247 18.599 -29.739 1.00 47.24 ? 177 THR B O 1 ATOM 2971 C CB . THR B 1 196 ? 26.581 16.354 -29.202 1.00 45.17 ? 177 THR B CB 1 ATOM 2972 O OG1 . THR B 1 196 ? 25.731 15.796 -30.216 1.00 50.98 ? 177 THR B OG1 1 ATOM 2973 C CG2 . THR B 1 196 ? 27.108 15.247 -28.321 1.00 42.76 ? 177 THR B CG2 1 ATOM 2974 N N . GLN B 1 197 ? 26.299 19.495 -29.455 1.00 46.08 ? 178 GLN B N 1 ATOM 2975 C CA . GLN B 1 197 ? 26.029 20.701 -30.236 1.00 43.03 ? 178 GLN B CA 1 ATOM 2976 C C . GLN B 1 197 ? 27.085 20.844 -31.333 1.00 42.20 ? 178 GLN B C 1 ATOM 2977 O O . GLN B 1 197 ? 28.263 20.582 -31.099 1.00 49.45 ? 178 GLN B O 1 ATOM 2978 C CB . GLN B 1 197 ? 26.052 21.943 -29.321 1.00 47.01 ? 178 GLN B CB 1 ATOM 2979 C CG . GLN B 1 197 ? 25.135 21.863 -28.088 1.00 51.08 ? 178 GLN B CG 1 ATOM 2980 C CD . GLN B 1 197 ? 24.707 23.242 -27.557 1.00 72.34 ? 178 GLN B CD 1 ATOM 2981 O OE1 . GLN B 1 197 ? 25.471 24.209 -27.634 1.00 70.32 ? 178 GLN B OE1 1 ATOM 2982 N NE2 . GLN B 1 197 ? 23.472 23.333 -27.024 1.00 64.06 ? 178 GLN B NE2 1 ATOM 2983 N N . LYS B 1 198 ? 26.689 21.250 -32.531 1.00 36.99 ? 179 LYS B N 1 ATOM 2984 C CA . LYS B 1 198 ? 27.696 21.638 -33.514 1.00 38.78 ? 179 LYS B CA 1 ATOM 2985 C C . LYS B 1 198 ? 27.195 22.768 -34.412 1.00 45.29 ? 179 LYS B C 1 ATOM 2986 O O . LYS B 1 198 ? 25.990 22.945 -34.589 1.00 42.62 ? 179 LYS B O 1 ATOM 2987 C CB . LYS B 1 198 ? 28.160 20.442 -34.351 1.00 37.96 ? 179 LYS B CB 1 ATOM 2988 C CG . LYS B 1 198 ? 27.360 20.236 -35.616 1.00 43.20 ? 179 LYS B CG 1 ATOM 2989 C CD . LYS B 1 198 ? 27.984 19.174 -36.490 1.00 52.49 ? 179 LYS B CD 1 ATOM 2990 C CE . LYS B 1 198 ? 27.060 18.824 -37.663 1.00 78.90 ? 179 LYS B CE 1 ATOM 2991 N NZ . LYS B 1 198 ? 27.646 17.775 -38.560 1.00 94.09 ? 179 LYS B NZ 1 ATOM 2992 N N . LYS B 1 199 ? 28.126 23.524 -34.986 1.00 48.34 ? 180 LYS B N 1 ATOM 2993 C CA . LYS B 1 199 ? 27.774 24.674 -35.809 1.00 37.71 ? 180 LYS B CA 1 ATOM 2994 C C . LYS B 1 199 ? 27.890 24.395 -37.312 1.00 38.04 ? 180 LYS B C 1 ATOM 2995 O O . LYS B 1 199 ? 28.864 23.812 -37.767 1.00 42.30 ? 180 LYS B O 1 ATOM 2996 C CB . LYS B 1 199 ? 28.656 25.856 -35.423 1.00 42.58 ? 180 LYS B CB 1 ATOM 2997 C CG . LYS B 1 199 ? 28.632 26.988 -36.426 1.00 50.23 ? 180 LYS B CG 1 ATOM 2998 C CD . LYS B 1 199 ? 29.523 28.121 -35.965 1.00 49.04 ? 180 LYS B CD 1 ATOM 2999 C CE . LYS B 1 199 ? 29.601 29.189 -37.037 1.00 62.10 ? 180 LYS B CE 1 ATOM 3000 N NZ . LYS B 1 199 ? 30.303 30.425 -36.553 1.00 74.13 ? 180 LYS B NZ 1 ATOM 3001 N N . ASN B 1 200 ? 26.887 24.803 -38.082 1.00 41.31 ? 181 ASN B N 1 ATOM 3002 C CA . ASN B 1 200 ? 26.942 24.669 -39.537 1.00 37.68 ? 181 ASN B CA 1 ATOM 3003 C C . ASN B 1 200 ? 26.898 26.032 -40.247 1.00 40.40 ? 181 ASN B C 1 ATOM 3004 O O . ASN B 1 200 ? 26.373 27.022 -39.729 1.00 40.44 ? 181 ASN B O 1 ATOM 3005 C CB . ASN B 1 200 ? 25.799 23.787 -40.071 1.00 45.65 ? 181 ASN B CB 1 ATOM 3006 C CG . ASN B 1 200 ? 25.672 22.457 -39.333 1.00 58.13 ? 181 ASN B CG 1 ATOM 3007 O OD1 . ASN B 1 200 ? 26.477 21.539 -39.534 1.00 59.13 ? 181 ASN B OD1 1 ATOM 3008 N ND2 . ASN B 1 200 ? 24.636 22.337 -38.492 1.00 58.33 ? 181 ASN B ND2 1 ATOM 3009 N N . SER B 1 201 ? 27.456 26.073 -41.445 1.00 39.91 ? 182 SER B N 1 ATOM 3010 C CA . SER B 1 201 ? 27.365 27.248 -42.286 1.00 30.32 ? 182 SER B CA 1 ATOM 3011 C C . SER B 1 201 ? 26.873 26.791 -43.660 1.00 39.10 ? 182 SER B C 1 ATOM 3012 O O . SER B 1 201 ? 27.571 26.051 -44.361 1.00 46.93 ? 182 SER B O 1 ATOM 3013 C CB . SER B 1 201 ? 28.724 27.895 -42.394 1.00 29.52 ? 182 SER B CB 1 ATOM 3014 O OG . SER B 1 201 ? 28.606 29.168 -42.989 1.00 46.40 ? 182 SER B OG 1 ATOM 3015 N N . VAL B 1 202 ? 25.664 27.213 -44.031 1.00 33.62 ? 183 VAL B N 1 ATOM 3016 C CA . VAL B 1 202 ? 24.961 26.646 -45.186 1.00 33.68 ? 183 VAL B CA 1 ATOM 3017 C C . VAL B 1 202 ? 24.702 27.699 -46.265 1.00 31.13 ? 183 VAL B C 1 ATOM 3018 O O . VAL B 1 202 ? 24.346 28.831 -45.948 1.00 34.02 ? 183 VAL B O 1 ATOM 3019 C CB . VAL B 1 202 ? 23.612 26.050 -44.747 1.00 26.15 ? 183 VAL B CB 1 ATOM 3020 C CG1 . VAL B 1 202 ? 22.834 25.532 -45.940 1.00 35.11 ? 183 VAL B CG1 1 ATOM 3021 C CG2 . VAL B 1 202 ? 23.827 24.977 -43.743 1.00 23.16 ? 183 VAL B CG2 1 ATOM 3022 N N . THR B 1 203 ? 24.892 27.338 -47.534 1.00 31.61 ? 184 THR B N 1 ATOM 3023 C CA . THR B 1 203 ? 24.504 28.228 -48.620 1.00 34.62 ? 184 THR B CA 1 ATOM 3024 C C . THR B 1 203 ? 23.237 27.708 -49.289 1.00 39.83 ? 184 THR B C 1 ATOM 3025 O O . THR B 1 203 ? 23.208 26.578 -49.777 1.00 43.01 ? 184 THR B O 1 ATOM 3026 C CB . THR B 1 203 ? 25.632 28.427 -49.647 1.00 39.27 ? 184 THR B CB 1 ATOM 3027 O OG1 . THR B 1 203 ? 26.692 29.183 -49.040 1.00 44.81 ? 184 THR B OG1 1 ATOM 3028 C CG2 . THR B 1 203 ? 25.122 29.187 -50.877 1.00 35.63 ? 184 THR B CG2 1 ATOM 3029 N N . TYR B 1 204 ? 22.189 28.534 -49.301 1.00 46.00 ? 185 TYR B N 1 ATOM 3030 C CA . TYR B 1 204 ? 20.910 28.171 -49.933 1.00 44.82 ? 185 TYR B CA 1 ATOM 3031 C C . TYR B 1 204 ? 20.813 28.609 -51.402 1.00 48.94 ? 185 TYR B C 1 ATOM 3032 O O . TYR B 1 204 ? 21.548 29.494 -51.852 1.00 60.82 ? 185 TYR B O 1 ATOM 3033 C CB . TYR B 1 204 ? 19.729 28.733 -49.131 1.00 41.83 ? 185 TYR B CB 1 ATOM 3034 C CG . TYR B 1 204 ? 19.655 28.193 -47.726 1.00 39.54 ? 185 TYR B CG 1 ATOM 3035 C CD1 . TYR B 1 204 ? 20.340 28.808 -46.685 1.00 37.97 ? 185 TYR B CD1 1 ATOM 3036 C CD2 . TYR B 1 204 ? 18.915 27.053 -47.440 1.00 42.95 ? 185 TYR B CD2 1 ATOM 3037 C CE1 . TYR B 1 204 ? 20.287 28.301 -45.389 1.00 38.61 ? 185 TYR B CE1 1 ATOM 3038 C CE2 . TYR B 1 204 ? 18.854 26.533 -46.148 1.00 31.69 ? 185 TYR B CE2 1 ATOM 3039 C CZ . TYR B 1 204 ? 19.541 27.160 -45.124 1.00 35.88 ? 185 TYR B CZ 1 ATOM 3040 O OH . TYR B 1 204 ? 19.493 26.658 -43.827 1.00 39.07 ? 185 TYR B OH 1 ATOM 3041 N N . SER B 1 205 ? 19.884 27.995 -52.131 1.00 45.06 ? 186 SER B N 1 ATOM 3042 C CA . SER B 1 205 ? 19.731 28.215 -53.572 1.00 51.89 ? 186 SER B CA 1 ATOM 3043 C C . SER B 1 205 ? 19.333 29.638 -53.944 1.00 57.64 ? 186 SER B C 1 ATOM 3044 O O . SER B 1 205 ? 19.476 30.057 -55.095 1.00 60.88 ? 186 SER B O 1 ATOM 3045 C CB . SER B 1 205 ? 18.727 27.221 -54.160 1.00 51.73 ? 186 SER B CB 1 ATOM 3046 O OG . SER B 1 205 ? 19.192 25.891 -54.018 1.00 62.04 ? 186 SER B OG 1 ATOM 3047 N N . CYS B 1 206 ? 18.844 30.381 -52.964 1.00 59.60 ? 187 CYS B N 1 ATOM 3048 C CA . CYS B 1 206 ? 18.351 31.724 -53.207 1.00 58.88 ? 187 CYS B CA 1 ATOM 3049 C C . CYS B 1 206 ? 19.465 32.791 -53.283 1.00 64.85 ? 187 CYS B C 1 ATOM 3050 O O . CYS B 1 206 ? 19.413 33.674 -54.135 1.00 83.57 ? 187 CYS B O 1 ATOM 3051 C CB . CYS B 1 206 ? 17.311 32.098 -52.138 1.00 68.88 ? 187 CYS B CB 1 ATOM 3052 S SG . CYS B 1 206 ? 18.021 32.664 -50.530 1.00 79.64 ? 187 CYS B SG 1 ATOM 3053 N N . CYS B 1 207 ? 20.470 32.706 -52.408 1.00 65.37 ? 188 CYS B N 1 ATOM 3054 C CA . CYS B 1 207 ? 21.448 33.794 -52.215 1.00 57.35 ? 188 CYS B CA 1 ATOM 3055 C C . CYS B 1 207 ? 22.896 33.284 -52.150 1.00 56.75 ? 188 CYS B C 1 ATOM 3056 O O . CYS B 1 207 ? 23.133 32.137 -51.766 1.00 58.91 ? 188 CYS B O 1 ATOM 3057 C CB . CYS B 1 207 ? 21.104 34.566 -50.934 1.00 64.57 ? 188 CYS B CB 1 ATOM 3058 S SG . CYS B 1 207 ? 19.478 34.078 -50.205 1.00 112.64 ? 188 CYS B SG 1 ATOM 3059 N N . PRO B 1 208 ? 23.870 34.139 -52.521 1.00 63.19 ? 189 PRO B N 1 ATOM 3060 C CA . PRO B 1 208 ? 25.293 33.760 -52.552 1.00 59.87 ? 189 PRO B CA 1 ATOM 3061 C C . PRO B 1 208 ? 25.950 33.819 -51.174 1.00 59.22 ? 189 PRO B C 1 ATOM 3062 O O . PRO B 1 208 ? 27.119 33.474 -51.028 1.00 61.93 ? 189 PRO B O 1 ATOM 3063 C CB . PRO B 1 208 ? 25.913 34.837 -53.455 1.00 62.98 ? 189 PRO B CB 1 ATOM 3064 C CG . PRO B 1 208 ? 25.085 36.046 -53.183 1.00 63.57 ? 189 PRO B CG 1 ATOM 3065 C CD . PRO B 1 208 ? 23.666 35.522 -53.000 1.00 65.23 ? 189 PRO B CD 1 ATOM 3066 N N . GLU B 1 209 ? 25.198 34.266 -50.177 1.00 63.90 ? 190 GLU B N 1 ATOM 3067 C CA . GLU B 1 209 ? 25.711 34.434 -48.820 1.00 55.60 ? 190 GLU B CA 1 ATOM 3068 C C . GLU B 1 209 ? 25.496 33.164 -47.996 1.00 54.98 ? 190 GLU B C 1 ATOM 3069 O O . GLU B 1 209 ? 24.612 32.358 -48.306 1.00 59.64 ? 190 GLU B O 1 ATOM 3070 C CB . GLU B 1 209 ? 24.988 35.608 -48.157 1.00 56.17 ? 190 GLU B CB 1 ATOM 3071 C CG . GLU B 1 209 ? 24.831 36.842 -49.060 1.00 62.29 ? 190 GLU B CG 1 ATOM 3072 C CD . GLU B 1 209 ? 26.097 37.690 -49.124 1.00 70.27 ? 190 GLU B CD 1 ATOM 3073 O OE1 . GLU B 1 209 ? 27.125 37.299 -48.517 1.00 68.82 ? 190 GLU B OE1 1 ATOM 3074 O OE2 . GLU B 1 209 ? 26.063 38.756 -49.776 1.00 71.80 ? 190 GLU B OE2 1 ATOM 3075 N N . ALA B 1 210 ? 26.293 32.984 -46.946 1.00 46.25 ? 191 ALA B N 1 ATOM 3076 C CA . ALA B 1 210 ? 26.140 31.818 -46.078 1.00 30.81 ? 191 ALA B CA 1 ATOM 3077 C C . ALA B 1 210 ? 25.292 32.168 -44.866 1.00 32.02 ? 191 ALA B C 1 ATOM 3078 O O . ALA B 1 210 ? 25.393 33.269 -44.331 1.00 37.35 ? 191 ALA B O 1 ATOM 3079 C CB . ALA B 1 210 ? 27.487 31.329 -45.630 1.00 37.25 ? 191 ALA B CB 1 ATOM 3080 N N . TYR B 1 211 ? 24.474 31.226 -44.415 1.00 33.09 ? 192 TYR B N 1 ATOM 3081 C CA . TYR B 1 211 ? 23.674 31.414 -43.198 1.00 29.38 ? 192 TYR B CA 1 ATOM 3082 C C . TYR B 1 211 ? 24.100 30.424 -42.124 1.00 28.58 ? 192 TYR B C 1 ATOM 3083 O O . TYR B 1 211 ? 24.023 29.208 -42.326 1.00 31.54 ? 192 TYR B O 1 ATOM 3084 C CB . TYR B 1 211 ? 22.190 31.224 -43.508 1.00 31.45 ? 192 TYR B CB 1 ATOM 3085 C CG . TYR B 1 211 ? 21.624 32.321 -44.355 1.00 27.60 ? 192 TYR B CG 1 ATOM 3086 C CD1 . TYR B 1 211 ? 21.891 32.387 -45.711 1.00 30.25 ? 192 TYR B CD1 1 ATOM 3087 C CD2 . TYR B 1 211 ? 20.833 33.306 -43.795 1.00 33.66 ? 192 TYR B CD2 1 ATOM 3088 C CE1 . TYR B 1 211 ? 21.378 33.417 -46.497 1.00 38.71 ? 192 TYR B CE1 1 ATOM 3089 C CE2 . TYR B 1 211 ? 20.314 34.350 -44.566 1.00 34.42 ? 192 TYR B CE2 1 ATOM 3090 C CZ . TYR B 1 211 ? 20.588 34.397 -45.920 1.00 37.47 ? 192 TYR B CZ 1 ATOM 3091 O OH . TYR B 1 211 ? 20.077 35.425 -46.694 1.00 39.09 ? 192 TYR B OH 1 ATOM 3092 N N . GLU B 1 212 ? 24.548 30.933 -40.983 1.00 24.95 ? 193 GLU B N 1 ATOM 3093 C CA . GLU B 1 212 ? 24.910 30.050 -39.870 1.00 31.03 ? 193 GLU B CA 1 ATOM 3094 C C . GLU B 1 212 ? 23.710 29.468 -39.096 1.00 28.70 ? 193 GLU B C 1 ATOM 3095 O O . GLU B 1 212 ? 22.663 30.104 -38.941 1.00 27.49 ? 193 GLU B O 1 ATOM 3096 C CB . GLU B 1 212 ? 25.861 30.754 -38.906 1.00 27.04 ? 193 GLU B CB 1 ATOM 3097 C CG . GLU B 1 212 ? 27.092 31.291 -39.579 1.00 34.20 ? 193 GLU B CG 1 ATOM 3098 C CD . GLU B 1 212 ? 28.105 31.848 -38.589 1.00 45.39 ? 193 GLU B CD 1 ATOM 3099 O OE1 . GLU B 1 212 ? 27.827 31.792 -37.370 1.00 44.73 ? 193 GLU B OE1 1 ATOM 3100 O OE2 . GLU B 1 212 ? 29.178 32.338 -39.027 1.00 50.60 ? 193 GLU B OE2 1 ATOM 3101 N N . ASP B 1 213 ? 23.880 28.247 -38.611 1.00 28.03 ? 194 ASP B N 1 ATOM 3102 C CA . ASP B 1 213 ? 22.932 27.657 -37.673 1.00 32.77 ? 194 ASP B CA 1 ATOM 3103 C C . ASP B 1 213 ? 23.643 26.740 -36.671 1.00 36.06 ? 194 ASP B C 1 ATOM 3104 O O . ASP B 1 213 ? 24.795 26.352 -36.871 1.00 31.43 ? 194 ASP B O 1 ATOM 3105 C CB . ASP B 1 213 ? 21.853 26.869 -38.404 1.00 29.89 ? 194 ASP B CB 1 ATOM 3106 C CG . ASP B 1 213 ? 22.440 25.805 -39.326 1.00 51.73 ? 194 ASP B CG 1 ATOM 3107 O OD1 . ASP B 1 213 ? 22.794 24.693 -38.834 1.00 51.06 ? 194 ASP B OD1 1 ATOM 3108 O OD2 . ASP B 1 213 ? 22.551 26.096 -40.549 1.00 57.33 ? 194 ASP B OD2 1 ATOM 3109 N N . VAL B 1 214 ? 22.941 26.414 -35.590 1.00 34.57 ? 195 VAL B N 1 ATOM 3110 C CA . VAL B 1 214 ? 23.416 25.447 -34.620 1.00 24.53 ? 195 VAL B CA 1 ATOM 3111 C C . VAL B 1 214 ? 22.517 24.218 -34.691 1.00 32.73 ? 195 VAL B C 1 ATOM 3112 O O . VAL B 1 214 ? 21.286 24.325 -34.784 1.00 27.18 ? 195 VAL B O 1 ATOM 3113 C CB . VAL B 1 214 ? 23.452 26.047 -33.209 1.00 21.18 ? 195 VAL B CB 1 ATOM 3114 C CG1 . VAL B 1 214 ? 23.683 24.978 -32.143 1.00 25.12 ? 195 VAL B CG1 1 ATOM 3115 C CG2 . VAL B 1 214 ? 24.524 27.112 -33.147 1.00 24.94 ? 195 VAL B CG2 1 ATOM 3116 N N . GLU B 1 215 ? 23.154 23.049 -34.696 1.00 38.65 ? 196 GLU B N 1 ATOM 3117 C CA . GLU B 1 215 ? 22.460 21.771 -34.713 1.00 33.74 ? 196 GLU B CA 1 ATOM 3118 C C . GLU B 1 215 ? 22.635 21.133 -33.338 1.00 34.17 ? 196 GLU B C 1 ATOM 3119 O O . GLU B 1 215 ? 23.764 20.926 -32.875 1.00 37.07 ? 196 GLU B O 1 ATOM 3120 C CB . GLU B 1 215 ? 23.064 20.877 -35.791 1.00 43.99 ? 196 GLU B CB 1 ATOM 3121 C CG . GLU B 1 215 ? 22.062 20.263 -36.755 1.00 55.09 ? 196 GLU B CG 1 ATOM 3122 C CD . GLU B 1 215 ? 22.731 19.426 -37.863 1.00 73.56 ? 196 GLU B CD 1 ATOM 3123 O OE1 . GLU B 1 215 ? 23.637 18.600 -37.553 1.00 70.08 ? 196 GLU B OE1 1 ATOM 3124 O OE2 . GLU B 1 215 ? 22.343 19.611 -39.044 1.00 66.27 ? 196 GLU B OE2 1 ATOM 3125 N N . VAL B 1 216 ? 21.524 20.846 -32.669 1.00 29.97 ? 197 VAL B N 1 ATOM 3126 C CA . VAL B 1 216 ? 21.584 20.235 -31.344 1.00 31.60 ? 197 VAL B CA 1 ATOM 3127 C C . VAL B 1 216 ? 21.072 18.793 -31.400 1.00 31.48 ? 197 VAL B C 1 ATOM 3128 O O . VAL B 1 216 ? 19.910 18.542 -31.751 1.00 25.79 ? 197 VAL B O 1 ATOM 3129 C CB . VAL B 1 216 ? 20.787 21.048 -30.304 1.00 28.11 ? 197 VAL B CB 1 ATOM 3130 C CG1 . VAL B 1 216 ? 20.820 20.355 -28.967 1.00 27.98 ? 197 VAL B CG1 1 ATOM 3131 C CG2 . VAL B 1 216 ? 21.351 22.438 -30.174 1.00 33.29 ? 197 VAL B CG2 1 ATOM 3132 N N . SER B 1 217 ? 21.949 17.849 -31.063 1.00 31.51 ? 198 SER B N 1 ATOM 3133 C CA . SER B 1 217 ? 21.615 16.432 -31.142 1.00 30.40 ? 198 SER B CA 1 ATOM 3134 C C . SER B 1 217 ? 21.205 15.923 -29.782 1.00 31.74 ? 198 SER B C 1 ATOM 3135 O O . SER B 1 217 ? 21.966 15.984 -28.813 1.00 33.61 ? 198 SER B O 1 ATOM 3136 C CB . SER B 1 217 ? 22.788 15.617 -31.674 1.00 29.06 ? 198 SER B CB 1 ATOM 3137 O OG . SER B 1 217 ? 23.185 16.108 -32.931 1.00 34.50 ? 198 SER B OG 1 ATOM 3138 N N . LEU B 1 218 ? 19.987 15.417 -29.718 1.00 31.95 ? 199 LEU B N 1 ATOM 3139 C CA . LEU B 1 218 ? 19.434 14.954 -28.461 1.00 38.16 ? 199 LEU B CA 1 ATOM 3140 C C . LEU B 1 218 ? 19.282 13.430 -28.486 1.00 38.75 ? 199 LEU B C 1 ATOM 3141 O O . LEU B 1 218 ? 18.434 12.878 -29.203 1.00 33.90 ? 199 LEU B O 1 ATOM 3142 C CB . LEU B 1 218 ? 18.096 15.643 -28.188 1.00 34.79 ? 199 LEU B CB 1 ATOM 3143 C CG . LEU B 1 218 ? 17.285 15.020 -27.052 1.00 36.67 ? 199 LEU B CG 1 ATOM 3144 C CD1 . LEU B 1 218 ? 18.028 15.185 -25.737 1.00 31.39 ? 199 LEU B CD1 1 ATOM 3145 C CD2 . LEU B 1 218 ? 15.881 15.615 -26.980 1.00 36.35 ? 199 LEU B CD2 1 ATOM 3146 N N . ASN B 1 219 ? 20.116 12.752 -27.706 1.00 37.15 ? 200 ASN B N 1 ATOM 3147 C CA . ASN B 1 219 ? 20.027 11.302 -27.605 1.00 39.35 ? 200 ASN B CA 1 ATOM 3148 C C . ASN B 1 219 ? 19.202 10.885 -26.370 1.00 38.04 ? 200 ASN B C 1 ATOM 3149 O O . ASN B 1 219 ? 19.585 11.163 -25.225 1.00 37.26 ? 200 ASN B O 1 ATOM 3150 C CB . ASN B 1 219 ? 21.436 10.689 -27.590 1.00 44.52 ? 200 ASN B CB 1 ATOM 3151 C CG . ASN B 1 219 ? 21.423 9.163 -27.624 1.00 42.14 ? 200 ASN B CG 1 ATOM 3152 O OD1 . ASN B 1 219 ? 22.177 8.515 -26.901 1.00 42.81 ? 200 ASN B OD1 1 ATOM 3153 N ND2 . ASN B 1 219 ? 20.557 8.588 -28.457 1.00 41.07 ? 200 ASN B ND2 1 ATOM 3154 N N . PHE B 1 220 ? 18.065 10.231 -26.611 1.00 33.71 ? 201 PHE B N 1 ATOM 3155 C CA . PHE B 1 220 ? 17.118 9.888 -25.544 1.00 33.16 ? 201 PHE B CA 1 ATOM 3156 C C . PHE B 1 220 ? 16.415 8.552 -25.819 1.00 35.44 ? 201 PHE B C 1 ATOM 3157 O O . PHE B 1 220 ? 16.348 8.097 -26.970 1.00 33.64 ? 201 PHE B O 1 ATOM 3158 C CB . PHE B 1 220 ? 16.062 10.993 -25.410 1.00 33.43 ? 201 PHE B CB 1 ATOM 3159 C CG . PHE B 1 220 ? 15.055 11.018 -26.543 1.00 32.01 ? 201 PHE B CG 1 ATOM 3160 C CD1 . PHE B 1 220 ? 15.433 11.400 -27.831 1.00 30.75 ? 201 PHE B CD1 1 ATOM 3161 C CD2 . PHE B 1 220 ? 13.730 10.656 -26.321 1.00 32.76 ? 201 PHE B CD2 1 ATOM 3162 C CE1 . PHE B 1 220 ? 14.511 11.413 -28.881 1.00 29.92 ? 201 PHE B CE1 1 ATOM 3163 C CE2 . PHE B 1 220 ? 12.794 10.674 -27.369 1.00 35.83 ? 201 PHE B CE2 1 ATOM 3164 C CZ . PHE B 1 220 ? 13.191 11.048 -28.651 1.00 30.94 ? 201 PHE B CZ 1 ATOM 3165 N N . ARG B 1 221 ? 15.880 7.932 -24.768 1.00 34.28 ? 202 ARG B N 1 ATOM 3166 C CA . ARG B 1 221 ? 15.088 6.706 -24.927 1.00 34.18 ? 202 ARG B CA 1 ATOM 3167 C C . ARG B 1 221 ? 13.980 6.623 -23.901 1.00 32.97 ? 202 ARG B C 1 ATOM 3168 O O . ARG B 1 221 ? 13.968 7.384 -22.922 1.00 38.30 ? 202 ARG B O 1 ATOM 3169 C CB . ARG B 1 221 ? 15.961 5.456 -24.790 1.00 35.22 ? 202 ARG B CB 1 ATOM 3170 C CG . ARG B 1 221 ? 16.666 5.386 -23.466 1.00 29.12 ? 202 ARG B CG 1 ATOM 3171 C CD . ARG B 1 221 ? 16.832 3.978 -22.996 1.00 32.28 ? 202 ARG B CD 1 ATOM 3172 N NE . ARG B 1 221 ? 17.510 3.963 -21.704 1.00 45.13 ? 202 ARG B NE 1 ATOM 3173 C CZ . ARG B 1 221 ? 18.783 3.629 -21.525 1.00 46.54 ? 202 ARG B CZ 1 ATOM 3174 N NH1 . ARG B 1 221 ? 19.519 3.243 -22.561 1.00 35.11 ? 202 ARG B NH1 1 ATOM 3175 N NH2 . ARG B 1 221 ? 19.312 3.667 -20.304 1.00 48.85 ? 202 ARG B NH2 1 ATOM 3176 N N . LYS B 1 222 ? 13.070 5.674 -24.122 1.00 35.46 ? 203 LYS B N 1 ATOM 3177 C CA . LYS B 1 222 ? 12.000 5.354 -23.171 1.00 32.95 ? 203 LYS B CA 1 ATOM 3178 C C . LYS B 1 222 ? 12.539 4.633 -21.932 1.00 33.87 ? 203 LYS B C 1 ATOM 3179 O O . LYS B 1 222 ? 13.443 3.792 -22.024 1.00 35.41 ? 203 LYS B O 1 ATOM 3180 C CB . LYS B 1 222 ? 10.934 4.499 -23.854 1.00 33.98 ? 203 LYS B CB 1 ATOM 3181 C CG . LYS B 1 222 ? 9.715 4.235 -22.999 1.00 50.32 ? 203 LYS B CG 1 ATOM 3182 C CD . LYS B 1 222 ? 8.666 3.488 -23.807 1.00 59.02 ? 203 LYS B CD 1 ATOM 3183 C CE . LYS B 1 222 ? 7.394 3.242 -23.008 1.00 71.43 ? 203 LYS B CE 1 ATOM 3184 N NZ . LYS B 1 222 ? 6.414 2.442 -23.807 1.00 68.35 ? 203 LYS B NZ 1 ATOM 3185 N N . LYS B 1 223 ? 11.989 4.972 -20.772 1.00 37.00 ? 204 LYS B N 1 ATOM 3186 C CA . LYS B 1 223 ? 12.427 4.379 -19.510 1.00 46.86 ? 204 LYS B CA 1 ATOM 3187 C C . LYS B 1 223 ? 11.929 2.944 -19.355 1.00 48.35 ? 204 LYS B C 1 ATOM 3188 O O . LYS B 1 223 ? 10.888 2.576 -19.931 1.00 48.92 ? 204 LYS B O 1 ATOM 3189 C CB . LYS B 1 223 ? 11.907 5.208 -18.331 1.00 40.54 ? 204 LYS B CB 1 ATOM 3190 C CG . LYS B 1 223 ? 12.617 6.525 -18.056 1.00 33.92 ? 204 LYS B CG 1 ATOM 3191 C CD . LYS B 1 223 ? 11.830 7.280 -16.998 1.00 30.00 ? 204 LYS B CD 1 ATOM 3192 C CE . LYS B 1 223 ? 12.672 8.301 -16.259 1.00 49.03 ? 204 LYS B CE 1 ATOM 3193 N NZ . LYS B 1 223 ? 11.950 8.818 -15.059 1.00 51.29 ? 204 LYS B NZ 1 ATOM 3194 N N . GLY B 1 224 ? 12.654 2.159 -18.555 1.00 47.26 ? 205 GLY B N 1 ATOM 3195 C CA . GLY B 1 224 ? 12.263 0.796 -18.210 1.00 52.81 ? 205 GLY B CA 1 ATOM 3196 C C . GLY B 1 224 ? 11.987 -0.118 -19.390 1.00 53.89 ? 205 GLY B C 1 ATOM 3197 O O . GLY B 1 224 ? 10.857 -0.188 -19.877 1.00 57.78 ? 205 GLY B O 1 ATOM 3198 N N . LEU C 1 20 ? 24.396 57.125 -45.136 1.00 56.56 ? 1 LEU C N 1 ATOM 3199 C CA . LEU C 1 20 ? 23.275 56.387 -44.584 1.00 44.88 ? 1 LEU C CA 1 ATOM 3200 C C . LEU C 1 20 ? 23.749 55.126 -43.879 1.00 46.43 ? 1 LEU C C 1 ATOM 3201 O O . LEU C 1 20 ? 24.527 54.346 -44.445 1.00 48.32 ? 1 LEU C O 1 ATOM 3202 C CB . LEU C 1 20 ? 22.323 55.978 -45.703 1.00 47.22 ? 1 LEU C CB 1 ATOM 3203 C CG . LEU C 1 20 ? 21.400 57.044 -46.252 1.00 38.02 ? 1 LEU C CG 1 ATOM 3204 C CD1 . LEU C 1 20 ? 20.394 56.375 -47.180 1.00 39.01 ? 1 LEU C CD1 1 ATOM 3205 C CD2 . LEU C 1 20 ? 20.713 57.760 -45.106 1.00 32.58 ? 1 LEU C CD2 1 ATOM 3206 N N . ASP C 1 21 ? 23.271 54.918 -42.656 1.00 40.78 ? 2 ASP C N 1 ATOM 3207 C CA . ASP C 1 21 ? 23.443 53.624 -41.991 1.00 42.92 ? 2 ASP C CA 1 ATOM 3208 C C . ASP C 1 21 ? 22.110 52.883 -41.895 1.00 38.35 ? 2 ASP C C 1 ATOM 3209 O O . ASP C 1 21 ? 21.082 53.402 -42.325 1.00 36.88 ? 2 ASP C O 1 ATOM 3210 C CB . ASP C 1 21 ? 24.089 53.780 -40.610 1.00 41.49 ? 2 ASP C CB 1 ATOM 3211 C CG . ASP C 1 21 ? 23.502 54.927 -39.815 1.00 54.44 ? 2 ASP C CG 1 ATOM 3212 O OD1 . ASP C 1 21 ? 22.264 55.096 -39.844 1.00 54.05 ? 2 ASP C OD1 1 ATOM 3213 O OD2 . ASP C 1 21 ? 24.281 55.663 -39.162 1.00 71.11 ? 2 ASP C OD2 1 ATOM 3214 N N . ARG C 1 22 ? 22.127 51.671 -41.349 1.00 39.81 ? 3 ARG C N 1 ATOM 3215 C CA . ARG C 1 22 ? 20.902 50.893 -41.236 1.00 31.50 ? 3 ARG C CA 1 ATOM 3216 C C . ARG C 1 22 ? 19.862 51.633 -40.432 1.00 29.88 ? 3 ARG C C 1 ATOM 3217 O O . ARG C 1 22 ? 18.685 51.622 -40.795 1.00 31.89 ? 3 ARG C O 1 ATOM 3218 C CB . ARG C 1 22 ? 21.160 49.533 -40.598 1.00 31.06 ? 3 ARG C CB 1 ATOM 3219 C CG . ARG C 1 22 ? 21.736 48.527 -41.549 1.00 31.17 ? 3 ARG C CG 1 ATOM 3220 C CD . ARG C 1 22 ? 21.953 47.200 -40.867 1.00 42.73 ? 3 ARG C CD 1 ATOM 3221 N NE . ARG C 1 22 ? 22.447 46.210 -41.816 1.00 47.05 ? 3 ARG C NE 1 ATOM 3222 C CZ . ARG C 1 22 ? 23.728 46.079 -42.132 1.00 51.09 ? 3 ARG C CZ 1 ATOM 3223 N NH1 . ARG C 1 22 ? 24.626 46.876 -41.558 1.00 59.49 ? 3 ARG C NH1 1 ATOM 3224 N NH2 . ARG C 1 22 ? 24.108 45.157 -43.014 1.00 47.10 ? 3 ARG C NH2 1 ATOM 3225 N N . ALA C 1 23 ? 20.293 52.285 -39.355 1.00 27.26 ? 4 ALA C N 1 ATOM 3226 C CA . ALA C 1 23 ? 19.358 53.004 -38.499 1.00 24.84 ? 4 ALA C CA 1 ATOM 3227 C C . ALA C 1 23 ? 18.578 54.074 -39.272 1.00 31.51 ? 4 ALA C C 1 ATOM 3228 O O . ALA C 1 23 ? 17.352 54.196 -39.136 1.00 31.98 ? 4 ALA C O 1 ATOM 3229 C CB . ALA C 1 23 ? 20.065 53.599 -37.335 1.00 21.47 ? 4 ALA C CB 1 ATOM 3230 N N . ASP C 1 24 ? 19.294 54.833 -40.095 1.00 31.19 ? 5 ASP C N 1 ATOM 3231 C CA . ASP C 1 24 ? 18.684 55.853 -40.948 1.00 29.75 ? 5 ASP C CA 1 ATOM 3232 C C . ASP C 1 24 ? 17.675 55.300 -41.976 1.00 29.10 ? 5 ASP C C 1 ATOM 3233 O O . ASP C 1 24 ? 16.561 55.816 -42.095 1.00 22.34 ? 5 ASP C O 1 ATOM 3234 C CB . ASP C 1 24 ? 19.780 56.667 -41.631 1.00 32.74 ? 5 ASP C CB 1 ATOM 3235 C CG . ASP C 1 24 ? 20.547 57.553 -40.645 1.00 55.18 ? 5 ASP C CG 1 ATOM 3236 O OD1 . ASP C 1 24 ? 19.906 58.023 -39.660 1.00 53.85 ? 5 ASP C OD1 1 ATOM 3237 O OD2 . ASP C 1 24 ? 21.777 57.774 -40.858 1.00 61.69 ? 5 ASP C OD2 1 ATOM 3238 N N . ILE C 1 25 ? 18.062 54.234 -42.685 1.00 27.82 ? 6 ILE C N 1 ATOM 3239 C CA . ILE C 1 25 ? 17.211 53.597 -43.693 1.00 22.77 ? 6 ILE C CA 1 ATOM 3240 C C . ILE C 1 25 ? 15.906 53.076 -43.095 1.00 26.53 ? 6 ILE C C 1 ATOM 3241 O O . ILE C 1 25 ? 14.807 53.351 -43.611 1.00 24.50 ? 6 ILE C O 1 ATOM 3242 C CB . ILE C 1 25 ? 17.945 52.444 -44.423 1.00 23.05 ? 6 ILE C CB 1 ATOM 3243 C CG1 . ILE C 1 25 ? 19.143 52.979 -45.190 1.00 27.10 ? 6 ILE C CG1 1 ATOM 3244 C CG2 . ILE C 1 25 ? 17.017 51.713 -45.401 1.00 19.60 ? 6 ILE C CG2 1 ATOM 3245 C CD1 . ILE C 1 25 ? 20.077 51.885 -45.652 1.00 33.26 ? 6 ILE C CD1 1 ATOM 3246 N N . LEU C 1 26 ? 16.029 52.328 -42.002 1.00 26.78 ? 7 LEU C N 1 ATOM 3247 C CA . LEU C 1 26 ? 14.860 51.763 -41.338 1.00 27.76 ? 7 LEU C CA 1 ATOM 3248 C C . LEU C 1 26 ? 13.950 52.869 -40.805 1.00 27.17 ? 7 LEU C C 1 ATOM 3249 O O . LEU C 1 26 ? 12.712 52.761 -40.839 1.00 28.27 ? 7 LEU C O 1 ATOM 3250 C CB . LEU C 1 26 ? 15.276 50.787 -40.235 1.00 27.47 ? 7 LEU C CB 1 ATOM 3251 C CG . LEU C 1 26 ? 15.906 49.513 -40.804 1.00 25.37 ? 7 LEU C CG 1 ATOM 3252 C CD1 . LEU C 1 26 ? 16.731 48.779 -39.769 1.00 25.49 ? 7 LEU C CD1 1 ATOM 3253 C CD2 . LEU C 1 26 ? 14.842 48.601 -41.360 1.00 21.82 ? 7 LEU C CD2 1 ATOM 3254 N N . TYR C 1 27 ? 14.565 53.953 -40.351 1.00 29.86 ? 8 TYR C N 1 ATOM 3255 C CA . TYR C 1 27 ? 13.802 55.127 -39.933 1.00 29.93 ? 8 TYR C CA 1 ATOM 3256 C C . TYR C 1 27 ? 12.966 55.692 -41.083 1.00 27.64 ? 8 TYR C C 1 ATOM 3257 O O . TYR C 1 27 ? 11.746 55.818 -40.970 1.00 24.43 ? 8 TYR C O 1 ATOM 3258 C CB . TYR C 1 27 ? 14.732 56.200 -39.379 1.00 31.74 ? 8 TYR C CB 1 ATOM 3259 C CG . TYR C 1 27 ? 14.000 57.425 -38.901 1.00 31.08 ? 8 TYR C CG 1 ATOM 3260 C CD1 . TYR C 1 27 ? 13.298 57.417 -37.708 1.00 32.81 ? 8 TYR C CD1 1 ATOM 3261 C CD2 . TYR C 1 27 ? 14.017 58.596 -39.645 1.00 38.62 ? 8 TYR C CD2 1 ATOM 3262 C CE1 . TYR C 1 27 ? 12.628 58.550 -37.264 1.00 41.76 ? 8 TYR C CE1 1 ATOM 3263 C CE2 . TYR C 1 27 ? 13.359 59.736 -39.215 1.00 45.22 ? 8 TYR C CE2 1 ATOM 3264 C CZ . TYR C 1 27 ? 12.662 59.711 -38.022 1.00 51.14 ? 8 TYR C CZ 1 ATOM 3265 O OH . TYR C 1 27 ? 12.002 60.850 -37.594 1.00 49.09 ? 8 TYR C OH 1 ATOM 3266 N N . ASN C 1 28 ? 13.625 56.019 -42.192 1.00 30.09 ? 9 ASN C N 1 ATOM 3267 C CA . ASN C 1 28 ? 12.917 56.525 -43.363 1.00 25.32 ? 9 ASN C CA 1 ATOM 3268 C C . ASN C 1 28 ? 11.825 55.588 -43.838 1.00 27.37 ? 9 ASN C C 1 ATOM 3269 O O . ASN C 1 28 ? 10.734 56.032 -44.188 1.00 28.33 ? 9 ASN C O 1 ATOM 3270 C CB . ASN C 1 28 ? 13.882 56.815 -44.501 1.00 24.26 ? 9 ASN C CB 1 ATOM 3271 C CG . ASN C 1 28 ? 14.897 57.863 -44.142 1.00 28.43 ? 9 ASN C CG 1 ATOM 3272 O OD1 . ASN C 1 28 ? 14.646 58.732 -43.288 1.00 26.50 ? 9 ASN C OD1 1 ATOM 3273 N ND2 . ASN C 1 28 ? 16.067 57.792 -44.787 1.00 29.71 ? 9 ASN C ND2 1 ATOM 3274 N N . ILE C 1 29 ? 12.109 54.289 -43.844 1.00 29.13 ? 10 ILE C N 1 ATOM 3275 C CA . ILE C 1 29 ? 11.084 53.321 -44.228 1.00 29.64 ? 10 ILE C CA 1 ATOM 3276 C C . ILE C 1 29 ? 9.874 53.338 -43.295 1.00 30.82 ? 10 ILE C C 1 ATOM 3277 O O . ILE C 1 29 ? 8.733 53.386 -43.753 1.00 33.22 ? 10 ILE C O 1 ATOM 3278 C CB . ILE C 1 29 ? 11.637 51.909 -44.357 1.00 26.44 ? 10 ILE C CB 1 ATOM 3279 C CG1 . ILE C 1 29 ? 12.625 51.869 -45.531 1.00 27.59 ? 10 ILE C CG1 1 ATOM 3280 C CG2 . ILE C 1 29 ? 10.491 50.914 -44.544 1.00 25.28 ? 10 ILE C CG2 1 ATOM 3281 C CD1 . ILE C 1 29 ? 13.265 50.508 -45.796 1.00 23.26 ? 10 ILE C CD1 1 ATOM 3282 N N . ARG C 1 30 ? 10.117 53.343 -41.990 1.00 28.60 ? 11 ARG C N 1 ATOM 3283 C CA . ARG C 1 30 ? 9.011 53.433 -41.047 1.00 28.26 ? 11 ARG C CA 1 ATOM 3284 C C . ARG C 1 30 ? 8.126 54.686 -41.239 1.00 34.25 ? 11 ARG C C 1 ATOM 3285 O O . ARG C 1 30 ? 6.909 54.619 -41.061 1.00 39.30 ? 11 ARG C O 1 ATOM 3286 C CB . ARG C 1 30 ? 9.513 53.326 -39.615 1.00 26.46 ? 11 ARG C CB 1 ATOM 3287 C CG . ARG C 1 30 ? 8.619 52.468 -38.767 1.00 45.30 ? 11 ARG C CG 1 ATOM 3288 C CD . ARG C 1 30 ? 8.520 52.977 -37.342 1.00 72.04 ? 11 ARG C CD 1 ATOM 3289 N NE . ARG C 1 30 ? 7.329 52.436 -36.689 1.00 87.10 ? 11 ARG C NE 1 ATOM 3290 C CZ . ARG C 1 30 ? 6.948 52.726 -35.447 1.00 89.02 ? 11 ARG C CZ 1 ATOM 3291 N NH1 . ARG C 1 30 ? 7.662 53.562 -34.698 1.00 84.78 ? 11 ARG C NH1 1 ATOM 3292 N NH2 . ARG C 1 30 ? 5.848 52.177 -34.952 1.00 88.62 ? 11 ARG C NH2 1 ATOM 3293 N N . GLN C 1 31 ? 8.729 55.808 -41.637 1.00 32.41 ? 12 GLN C N 1 ATOM 3294 C CA . GLN C 1 31 ? 8.007 57.082 -41.768 1.00 30.44 ? 12 GLN C CA 1 ATOM 3295 C C . GLN C 1 31 ? 7.239 57.297 -43.076 1.00 32.45 ? 12 GLN C C 1 ATOM 3296 O O . GLN C 1 31 ? 6.315 58.101 -43.116 1.00 36.76 ? 12 GLN C O 1 ATOM 3297 C CB . GLN C 1 31 ? 8.967 58.266 -41.576 1.00 33.20 ? 12 GLN C CB 1 ATOM 3298 C CG . GLN C 1 31 ? 9.694 58.312 -40.237 1.00 38.57 ? 12 GLN C CG 1 ATOM 3299 C CD . GLN C 1 31 ? 8.748 58.518 -39.056 1.00 49.22 ? 12 GLN C CD 1 ATOM 3300 O OE1 . GLN C 1 31 ? 7.597 58.940 -39.226 1.00 54.34 ? 12 GLN C OE1 1 ATOM 3301 N NE2 . GLN C 1 31 ? 9.230 58.212 -37.852 1.00 44.09 ? 12 GLN C NE2 1 ATOM 3302 N N . THR C 1 32 ? 7.622 56.597 -44.141 1.00 27.43 ? 13 THR C N 1 ATOM 3303 C CA . THR C 1 32 ? 7.155 56.953 -45.477 1.00 27.41 ? 13 THR C CA 1 ATOM 3304 C C . THR C 1 32 ? 6.600 55.795 -46.299 1.00 37.00 ? 13 THR C C 1 ATOM 3305 O O . THR C 1 32 ? 6.282 55.951 -47.489 1.00 40.10 ? 13 THR C O 1 ATOM 3306 C CB . THR C 1 32 ? 8.302 57.586 -46.305 1.00 28.68 ? 13 THR C CB 1 ATOM 3307 O OG1 . THR C 1 32 ? 9.359 56.629 -46.491 1.00 30.41 ? 13 THR C OG1 1 ATOM 3308 C CG2 . THR C 1 32 ? 8.840 58.828 -45.624 1.00 28.66 ? 13 THR C CG2 1 ATOM 3309 N N . SER C 1 33 ? 6.536 54.636 -45.689 1.00 45.51 ? 14 SER C N 1 ATOM 3310 C CA . SER C 1 33 ? 6.292 53.386 -46.398 1.00 45.50 ? 14 SER C CA 1 ATOM 3311 C C . SER C 1 33 ? 4.944 53.180 -47.072 1.00 45.18 ? 14 SER C C 1 ATOM 3312 O O . SER C 1 33 ? 4.887 52.689 -48.181 1.00 33.87 ? 14 SER C O 1 ATOM 3313 C CB . SER C 1 33 ? 6.570 52.240 -45.461 1.00 37.94 ? 14 SER C CB 1 ATOM 3314 O OG . SER C 1 33 ? 6.322 51.058 -46.117 1.00 38.40 ? 14 SER C OG 1 ATOM 3315 N N . ARG C 1 34 ? 3.867 53.587 -46.409 1.00 43.81 ? 15 ARG C N 1 ATOM 3316 C CA . ARG C 1 34 ? 2.517 53.389 -46.905 1.00 34.04 ? 15 ARG C CA 1 ATOM 3317 C C . ARG C 1 34 ? 2.104 51.965 -47.162 1.00 33.83 ? 15 ARG C C 1 ATOM 3318 O O . ARG C 1 34 ? 1.970 51.539 -48.259 1.00 37.50 ? 15 ARG C O 1 ATOM 3319 C CB . ARG C 1 34 ? 2.233 54.262 -48.103 1.00 37.97 ? 15 ARG C CB 1 ATOM 3320 C CG . ARG C 1 34 ? 2.252 55.739 -47.813 1.00 35.57 ? 15 ARG C CG 1 ATOM 3321 C CD . ARG C 1 34 ? 1.226 56.134 -46.778 1.00 42.22 ? 15 ARG C CD 1 ATOM 3322 N NE . ARG C 1 34 ? -0.133 56.117 -47.306 1.00 47.11 ? 15 ARG C NE 1 ATOM 3323 C CZ . ARG C 1 34 ? -0.662 57.020 -48.112 1.00 39.84 ? 15 ARG C CZ 1 ATOM 3324 N NH1 . ARG C 1 34 ? 0.031 58.050 -48.526 1.00 30.90 ? 15 ARG C NH1 1 ATOM 3325 N NH2 . ARG C 1 34 ? -1.888 56.874 -48.520 1.00 30.62 ? 15 ARG C NH2 1 ATOM 3326 N N . PRO C 1 35 ? 1.908 51.216 -46.027 1.00 26.49 ? 16 PRO C N 1 ATOM 3327 C CA . PRO C 1 35 ? 1.641 49.804 -46.228 1.00 23.98 ? 16 PRO C CA 1 ATOM 3328 C C . PRO C 1 35 ? 0.327 49.484 -46.863 1.00 24.60 ? 16 PRO C C 1 ATOM 3329 O O . PRO C 1 35 ? 0.044 48.365 -47.150 1.00 23.26 ? 16 PRO C O 1 ATOM 3330 C CB . PRO C 1 35 ? 1.592 49.275 -44.821 1.00 26.17 ? 16 PRO C CB 1 ATOM 3331 C CG . PRO C 1 35 ? 2.374 50.185 -44.043 1.00 28.56 ? 16 PRO C CG 1 ATOM 3332 C CD . PRO C 1 35 ? 1.849 51.437 -44.527 1.00 31.01 ? 16 PRO C CD 1 ATOM 3333 N N . ASP C 1 36 ? -0.535 50.461 -46.927 1.00 28.96 ? 17 ASP C N 1 ATOM 3334 C CA . ASP C 1 36 ? -1.873 50.270 -47.408 1.00 25.94 ? 17 ASP C CA 1 ATOM 3335 C C . ASP C 1 36 ? -2.006 50.540 -48.876 1.00 26.25 ? 17 ASP C C 1 ATOM 3336 O O . ASP C 1 36 ? -3.010 50.286 -49.464 1.00 24.86 ? 17 ASP C O 1 ATOM 3337 C CB . ASP C 1 36 ? -2.842 51.106 -46.567 1.00 28.14 ? 17 ASP C CB 1 ATOM 3338 C CG . ASP C 1 36 ? -2.489 52.580 -46.513 1.00 42.90 ? 17 ASP C CG 1 ATOM 3339 O OD1 . ASP C 1 36 ? -1.342 52.960 -46.270 1.00 40.36 ? 17 ASP C OD1 1 ATOM 3340 O OD2 . ASP C 1 36 ? -3.405 53.386 -46.675 1.00 45.35 ? 17 ASP C OD2 1 ATOM 3341 N N . VAL C 1 37 ? -0.941 51.040 -49.462 1.00 24.93 ? 18 VAL C N 1 ATOM 3342 C CA . VAL C 1 37 ? -0.919 51.500 -50.865 1.00 27.98 ? 18 VAL C CA 1 ATOM 3343 C C . VAL C 1 37 ? -0.119 50.587 -51.790 1.00 24.06 ? 18 VAL C C 1 ATOM 3344 O O . VAL C 1 37 ? 1.109 50.505 -51.688 1.00 25.53 ? 18 VAL C O 1 ATOM 3345 C CB . VAL C 1 37 ? -0.303 52.911 -51.011 1.00 22.70 ? 18 VAL C CB 1 ATOM 3346 C CG1 . VAL C 1 37 ? -0.218 53.288 -52.468 1.00 16.59 ? 18 VAL C CG1 1 ATOM 3347 C CG2 . VAL C 1 37 ? -1.074 53.920 -50.211 1.00 25.60 ? 18 VAL C CG2 1 ATOM 3348 N N . ILE C 1 38 ? -0.818 49.925 -52.704 1.00 20.08 ? 19 ILE C N 1 ATOM 3349 C CA . ILE C 1 38 ? -0.177 49.082 -53.714 1.00 22.26 ? 19 ILE C CA 1 ATOM 3350 C C . ILE C 1 38 ? 0.785 49.878 -54.606 1.00 25.02 ? 19 ILE C C 1 ATOM 3351 O O . ILE C 1 38 ? 0.400 50.901 -55.171 1.00 32.15 ? 19 ILE C O 1 ATOM 3352 C CB . ILE C 1 38 ? -1.256 48.337 -54.549 1.00 25.91 ? 19 ILE C CB 1 ATOM 3353 C CG1 . ILE C 1 38 ? -0.631 47.352 -55.541 1.00 25.46 ? 19 ILE C CG1 1 ATOM 3354 C CG2 . ILE C 1 38 ? -2.210 49.310 -55.242 1.00 19.48 ? 19 ILE C CG2 1 ATOM 3355 C CD1 . ILE C 1 38 ? -1.667 46.419 -56.181 1.00 23.98 ? 19 ILE C CD1 1 ATOM 3356 N N . PRO C 1 39 ? 2.053 49.418 -54.724 1.00 30.32 ? 20 PRO C N 1 ATOM 3357 C CA . PRO C 1 39 ? 3.106 50.152 -55.460 1.00 31.89 ? 20 PRO C CA 1 ATOM 3358 C C . PRO C 1 39 ? 3.049 49.962 -56.982 1.00 33.10 ? 20 PRO C C 1 ATOM 3359 O O . PRO C 1 39 ? 4.000 49.456 -57.588 1.00 33.36 ? 20 PRO C O 1 ATOM 3360 C CB . PRO C 1 39 ? 4.409 49.559 -54.889 1.00 30.59 ? 20 PRO C CB 1 ATOM 3361 C CG . PRO C 1 39 ? 4.055 48.142 -54.537 1.00 23.58 ? 20 PRO C CG 1 ATOM 3362 C CD . PRO C 1 39 ? 2.575 48.174 -54.117 1.00 27.37 ? 20 PRO C CD 1 ATOM 3363 N N . THR C 1 40 ? 1.928 50.347 -57.585 1.00 36.60 ? 21 THR C N 1 ATOM 3364 C CA . THR C 1 40 ? 1.785 50.285 -59.033 1.00 44.75 ? 21 THR C CA 1 ATOM 3365 C C . THR C 1 40 ? 2.672 51.343 -59.692 1.00 53.63 ? 21 THR C C 1 ATOM 3366 O O . THR C 1 40 ? 2.953 52.387 -59.108 1.00 48.15 ? 21 THR C O 1 ATOM 3367 C CB . THR C 1 40 ? 0.327 50.504 -59.463 1.00 47.26 ? 21 THR C CB 1 ATOM 3368 O OG1 . THR C 1 40 ? -0.170 51.716 -58.872 1.00 55.62 ? 21 THR C OG1 1 ATOM 3369 C CG2 . THR C 1 40 ? -0.542 49.355 -59.012 1.00 34.87 ? 21 THR C CG2 1 ATOM 3370 N N . GLN C 1 41 ? 3.158 51.023 -60.868 1.00 66.47 ? 22 GLN C N 1 ATOM 3371 C CA . GLN C 1 41 ? 3.924 51.957 -61.624 1.00 74.38 ? 22 GLN C CA 1 ATOM 3372 C C . GLN C 1 41 ? 3.156 52.243 -62.881 1.00 81.70 ? 22 GLN C C 1 ATOM 3373 O O . GLN C 1 41 ? 2.998 51.377 -63.720 1.00 80.99 ? 22 GLN C O 1 ATOM 3374 C CB . GLN C 1 41 ? 5.224 51.298 -62.010 1.00 70.73 ? 22 GLN C CB 1 ATOM 3375 C CG . GLN C 1 41 ? 6.278 51.292 -60.926 1.00 74.10 ? 22 GLN C CG 1 ATOM 3376 C CD . GLN C 1 41 ? 7.615 50.857 -61.467 1.00 82.04 ? 22 GLN C CD 1 ATOM 3377 O OE1 . GLN C 1 41 ? 7.733 49.776 -62.005 1.00 70.60 ? 22 GLN C OE1 1 ATOM 3378 N NE2 . GLN C 1 41 ? 8.627 51.708 -61.337 1.00 73.75 ? 22 GLN C NE2 1 ATOM 3379 N N . ARG C 1 42 ? 2.696 53.468 -63.032 1.00 76.25 ? 23 ARG C N 1 ATOM 3380 C CA . ARG C 1 42 ? 2.055 53.848 -64.264 1.00 84.13 ? 23 ARG C CA 1 ATOM 3381 C C . ARG C 1 42 ? 0.932 52.905 -64.570 1.00 80.44 ? 23 ARG C C 1 ATOM 3382 O O . ARG C 1 42 ? 0.709 52.538 -65.700 1.00 80.03 ? 23 ARG C O 1 ATOM 3383 C CB . ARG C 1 42 ? 3.074 53.890 -65.393 1.00 91.54 ? 23 ARG C CB 1 ATOM 3384 C CG . ARG C 1 42 ? 4.124 54.944 -65.131 1.00 93.06 ? 23 ARG C CG 1 ATOM 3385 C CD . ARG C 1 42 ? 5.195 55.026 -66.192 1.00 95.11 ? 23 ARG C CD 1 ATOM 3386 N NE . ARG C 1 42 ? 6.349 55.782 -65.713 1.00 104.22 ? 23 ARG C NE 1 ATOM 3387 C CZ . ARG C 1 42 ? 7.030 56.650 -66.445 1.00 103.15 ? 23 ARG C CZ 1 ATOM 3388 N NH1 . ARG C 1 42 ? 6.674 56.908 -67.689 1.00 100.69 ? 23 ARG C NH1 1 ATOM 3389 N NH2 . ARG C 1 42 ? 8.058 57.275 -65.923 1.00 103.07 ? 23 ARG C NH2 1 ATOM 3390 N N . ASP C 1 43 ? 0.217 52.512 -63.536 1.00 86.40 ? 24 ASP C N 1 ATOM 3391 C CA . ASP C 1 43 ? -0.967 51.665 -63.703 1.00 87.02 ? 24 ASP C CA 1 ATOM 3392 C C . ASP C 1 43 ? -0.686 50.433 -64.529 1.00 77.41 ? 24 ASP C C 1 ATOM 3393 O O . ASP C 1 43 ? -1.383 50.122 -65.458 1.00 80.61 ? 24 ASP C O 1 ATOM 3394 C CB . ASP C 1 43 ? -2.179 52.463 -64.177 1.00 99.04 ? 24 ASP C CB 1 ATOM 3395 C CG . ASP C 1 43 ? -2.557 53.546 -63.193 1.00 112.62 ? 24 ASP C CG 1 ATOM 3396 O OD1 . ASP C 1 43 ? -1.656 53.968 -62.447 1.00 97.29 ? 24 ASP C OD1 1 ATOM 3397 O OD2 . ASP C 1 43 ? -3.728 53.965 -63.147 1.00 119.37 ? 24 ASP C OD2 1 ATOM 3398 N N . ARG C 1 44 ? 0.383 49.761 -64.146 1.00 75.98 ? 25 ARG C N 1 ATOM 3399 C CA . ARG C 1 44 ? 0.798 48.506 -64.688 1.00 62.76 ? 25 ARG C CA 1 ATOM 3400 C C . ARG C 1 44 ? 0.788 47.668 -63.468 1.00 49.83 ? 25 ARG C C 1 ATOM 3401 O O . ARG C 1 44 ? 0.890 48.172 -62.374 1.00 50.28 ? 25 ARG C O 1 ATOM 3402 C CB . ARG C 1 44 ? 2.203 48.607 -65.256 1.00 68.38 ? 25 ARG C CB 1 ATOM 3403 C CG . ARG C 1 44 ? 2.425 49.946 -65.936 1.00 87.31 ? 25 ARG C CG 1 ATOM 3404 C CD . ARG C 1 44 ? 3.566 50.052 -66.924 1.00 104.01 ? 25 ARG C CD 1 ATOM 3405 N NE . ARG C 1 44 ? 3.615 51.421 -67.430 1.00 114.71 ? 25 ARG C NE 1 ATOM 3406 C CZ . ARG C 1 44 ? 4.182 51.794 -68.571 1.00 113.63 ? 25 ARG C CZ 1 ATOM 3407 N NH1 . ARG C 1 44 ? 4.767 50.897 -69.344 1.00 113.14 ? 25 ARG C NH1 1 ATOM 3408 N NH2 . ARG C 1 44 ? 4.160 53.069 -68.940 1.00 107.04 ? 25 ARG C NH2 1 ATOM 3409 N N . PRO C 1 45 ? 0.608 46.324 -63.694 1.00 44.26 ? 26 PRO C N 1 ATOM 3410 C CA . PRO C 1 45 ? 0.517 45.511 -62.493 1.00 40.11 ? 26 PRO C CA 1 ATOM 3411 C C . PRO C 1 45 ? 1.772 45.491 -61.695 1.00 38.97 ? 26 PRO C C 1 ATOM 3412 O O . PRO C 1 45 ? 2.823 45.761 -62.211 1.00 40.81 ? 26 PRO C O 1 ATOM 3413 C CB . PRO C 1 45 ? 0.343 44.120 -63.031 1.00 36.68 ? 26 PRO C CB 1 ATOM 3414 C CG . PRO C 1 45 ? -0.326 44.284 -64.275 1.00 38.46 ? 26 PRO C CG 1 ATOM 3415 C CD . PRO C 1 45 ? 0.363 45.401 -64.882 1.00 42.16 ? 26 PRO C CD 1 ATOM 3416 N N . VAL C 1 46 ? 1.657 45.179 -60.418 1.00 31.09 ? 27 VAL C N 1 ATOM 3417 C CA . VAL C 1 46 ? 2.840 44.816 -59.667 1.00 23.52 ? 27 VAL C CA 1 ATOM 3418 C C . VAL C 1 46 ? 3.094 43.362 -60.022 1.00 28.01 ? 27 VAL C C 1 ATOM 3419 O O . VAL C 1 46 ? 2.194 42.514 -59.908 1.00 26.50 ? 27 VAL C O 1 ATOM 3420 C CB . VAL C 1 46 ? 2.585 44.935 -58.164 1.00 23.24 ? 27 VAL C CB 1 ATOM 3421 C CG1 . VAL C 1 46 ? 3.813 44.500 -57.357 1.00 22.90 ? 27 VAL C CG1 1 ATOM 3422 C CG2 . VAL C 1 46 ? 2.166 46.347 -57.809 1.00 27.43 ? 27 VAL C CG2 1 ATOM 3423 N N . ALA C 1 47 ? 4.299 43.054 -60.473 1.00 26.84 ? 28 ALA C N 1 ATOM 3424 C CA . ALA C 1 47 ? 4.590 41.659 -60.802 1.00 32.06 ? 28 ALA C CA 1 ATOM 3425 C C . ALA C 1 47 ? 5.058 40.908 -59.562 1.00 29.46 ? 28 ALA C C 1 ATOM 3426 O O . ALA C 1 47 ? 6.155 41.150 -59.053 1.00 30.85 ? 28 ALA C O 1 ATOM 3427 C CB . ALA C 1 47 ? 5.622 41.556 -61.910 1.00 35.73 ? 28 ALA C CB 1 ATOM 3428 N N . VAL C 1 48 ? 4.225 39.994 -59.083 1.00 23.19 ? 29 VAL C N 1 ATOM 3429 C CA . VAL C 1 48 ? 4.581 39.182 -57.931 1.00 25.53 ? 29 VAL C CA 1 ATOM 3430 C C . VAL C 1 48 ? 5.026 37.781 -58.392 1.00 27.20 ? 29 VAL C C 1 ATOM 3431 O O . VAL C 1 48 ? 4.334 37.132 -59.162 1.00 33.43 ? 29 VAL C O 1 ATOM 3432 C CB . VAL C 1 48 ? 3.379 39.058 -56.953 1.00 25.50 ? 29 VAL C CB 1 ATOM 3433 C CG1 . VAL C 1 48 ? 3.766 38.265 -55.714 1.00 22.51 ? 29 VAL C CG1 1 ATOM 3434 C CG2 . VAL C 1 48 ? 2.851 40.411 -56.562 1.00 20.52 ? 29 VAL C CG2 1 ATOM 3435 N N . SER C 1 49 ? 6.172 37.308 -57.919 1.00 28.19 ? 30 SER C N 1 ATOM 3436 C CA . SER C 1 49 ? 6.594 35.940 -58.197 1.00 22.36 ? 30 SER C CA 1 ATOM 3437 C C . SER C 1 49 ? 6.342 35.100 -56.969 1.00 28.75 ? 30 SER C C 1 ATOM 3438 O O . SER C 1 49 ? 6.617 35.532 -55.837 1.00 31.60 ? 30 SER C O 1 ATOM 3439 C CB . SER C 1 49 ? 8.077 35.880 -58.512 1.00 20.07 ? 30 SER C CB 1 ATOM 3440 O OG . SER C 1 49 ? 8.450 36.959 -59.331 1.00 37.88 ? 30 SER C OG 1 ATOM 3441 N N . VAL C 1 50 ? 5.842 33.891 -57.191 1.00 26.38 ? 31 VAL C N 1 ATOM 3442 C CA . VAL C 1 50 ? 5.523 32.988 -56.105 1.00 26.47 ? 31 VAL C CA 1 ATOM 3443 C C . VAL C 1 50 ? 6.182 31.647 -56.332 1.00 31.16 ? 31 VAL C C 1 ATOM 3444 O O . VAL C 1 50 ? 6.086 31.088 -57.415 1.00 44.70 ? 31 VAL C O 1 ATOM 3445 C CB . VAL C 1 50 ? 4.012 32.767 -55.985 1.00 26.44 ? 31 VAL C CB 1 ATOM 3446 C CG1 . VAL C 1 50 ? 3.721 31.827 -54.833 1.00 35.30 ? 31 VAL C CG1 1 ATOM 3447 C CG2 . VAL C 1 50 ? 3.300 34.094 -55.774 1.00 23.36 ? 31 VAL C CG2 1 ATOM 3448 N N . SER C 1 51 ? 6.837 31.120 -55.305 1.00 31.40 ? 32 SER C N 1 ATOM 3449 C CA . SER C 1 51 ? 7.452 29.804 -55.393 1.00 30.02 ? 32 SER C CA 1 ATOM 3450 C C . SER C 1 51 ? 7.297 29.039 -54.075 1.00 28.74 ? 32 SER C C 1 ATOM 3451 O O . SER C 1 51 ? 7.677 29.555 -53.023 1.00 35.38 ? 32 SER C O 1 ATOM 3452 C CB . SER C 1 51 ? 8.931 29.967 -55.735 1.00 35.32 ? 32 SER C CB 1 ATOM 3453 O OG . SER C 1 51 ? 9.565 28.708 -55.869 1.00 50.36 ? 32 SER C OG 1 ATOM 3454 N N . LEU C 1 52 ? 6.744 27.825 -54.122 1.00 25.80 ? 33 LEU C N 1 ATOM 3455 C CA . LEU C 1 52 ? 6.653 26.981 -52.920 1.00 26.22 ? 33 LEU C CA 1 ATOM 3456 C C . LEU C 1 52 ? 7.826 25.999 -52.828 1.00 31.40 ? 33 LEU C C 1 ATOM 3457 O O . LEU C 1 52 ? 8.134 25.301 -53.796 1.00 41.64 ? 33 LEU C O 1 ATOM 3458 C CB . LEU C 1 52 ? 5.335 26.200 -52.874 1.00 20.63 ? 33 LEU C CB 1 ATOM 3459 C CG . LEU C 1 52 ? 4.082 27.035 -53.101 1.00 23.38 ? 33 LEU C CG 1 ATOM 3460 C CD1 . LEU C 1 52 ? 2.812 26.256 -52.789 1.00 20.72 ? 33 LEU C CD1 1 ATOM 3461 C CD2 . LEU C 1 52 ? 4.130 28.318 -52.294 1.00 23.89 ? 33 LEU C CD2 1 ATOM 3462 N N . LYS C 1 53 ? 8.483 25.950 -51.671 1.00 27.68 ? 34 LYS C N 1 ATOM 3463 C CA . LYS C 1 53 ? 9.492 24.925 -51.407 1.00 27.01 ? 34 LYS C CA 1 ATOM 3464 C C . LYS C 1 53 ? 8.939 23.996 -50.347 1.00 31.37 ? 34 LYS C C 1 ATOM 3465 O O . LYS C 1 53 ? 8.766 24.408 -49.186 1.00 29.21 ? 34 LYS C O 1 ATOM 3466 C CB . LYS C 1 53 ? 10.784 25.541 -50.883 1.00 33.62 ? 34 LYS C CB 1 ATOM 3467 C CG . LYS C 1 53 ? 11.207 26.821 -51.578 1.00 40.19 ? 34 LYS C CG 1 ATOM 3468 C CD . LYS C 1 53 ? 11.771 26.555 -52.958 1.00 46.52 ? 34 LYS C CD 1 ATOM 3469 C CE . LYS C 1 53 ? 12.148 27.873 -53.638 1.00 60.79 ? 34 LYS C CE 1 ATOM 3470 N NZ . LYS C 1 53 ? 12.671 27.659 -55.027 1.00 70.12 ? 34 LYS C NZ 1 ATOM 3471 N N . PHE C 1 54 ? 8.657 22.749 -50.730 1.00 30.07 ? 35 PHE C N 1 ATOM 3472 C CA . PHE C 1 54 ? 8.053 21.820 -49.784 1.00 24.15 ? 35 PHE C CA 1 ATOM 3473 C C . PHE C 1 54 ? 9.029 21.326 -48.735 1.00 24.18 ? 35 PHE C C 1 ATOM 3474 O O . PHE C 1 54 ? 10.156 20.968 -49.045 1.00 27.24 ? 35 PHE C O 1 ATOM 3475 C CB . PHE C 1 54 ? 7.356 20.693 -50.514 1.00 23.17 ? 35 PHE C CB 1 ATOM 3476 C CG . PHE C 1 54 ? 6.215 21.170 -51.329 1.00 26.84 ? 35 PHE C CG 1 ATOM 3477 C CD1 . PHE C 1 54 ? 4.965 21.373 -50.745 1.00 26.48 ? 35 PHE C CD1 1 ATOM 3478 C CD2 . PHE C 1 54 ? 6.400 21.493 -52.666 1.00 31.06 ? 35 PHE C CD2 1 ATOM 3479 C CE1 . PHE C 1 54 ? 3.903 21.857 -51.502 1.00 28.82 ? 35 PHE C CE1 1 ATOM 3480 C CE2 . PHE C 1 54 ? 5.348 21.978 -53.440 1.00 31.08 ? 35 PHE C CE2 1 ATOM 3481 C CZ . PHE C 1 54 ? 4.099 22.162 -52.862 1.00 32.97 ? 35 PHE C CZ 1 ATOM 3482 N N . ILE C 1 55 ? 8.593 21.356 -47.481 1.00 21.32 ? 36 ILE C N 1 ATOM 3483 C CA . ILE C 1 55 ? 9.447 20.945 -46.386 1.00 21.84 ? 36 ILE C CA 1 ATOM 3484 C C . ILE C 1 55 ? 8.973 19.632 -45.769 1.00 23.77 ? 36 ILE C C 1 ATOM 3485 O O . ILE C 1 55 ? 9.796 18.790 -45.403 1.00 27.67 ? 36 ILE C O 1 ATOM 3486 C CB . ILE C 1 55 ? 9.542 22.033 -45.299 1.00 22.60 ? 36 ILE C CB 1 ATOM 3487 C CG1 . ILE C 1 55 ? 9.829 23.404 -45.925 1.00 26.48 ? 36 ILE C CG1 1 ATOM 3488 C CG2 . ILE C 1 55 ? 10.606 21.662 -44.292 1.00 21.32 ? 36 ILE C CG2 1 ATOM 3489 C CD1 . ILE C 1 55 ? 11.102 23.451 -46.799 1.00 26.48 ? 36 ILE C CD1 1 ATOM 3490 N N . ASN C 1 56 ? 7.654 19.458 -45.656 1.00 18.24 ? 37 ASN C N 1 ATOM 3491 C CA . ASN C 1 56 ? 7.101 18.252 -45.051 1.00 18.81 ? 37 ASN C CA 1 ATOM 3492 C C . ASN C 1 56 ? 5.682 17.938 -45.491 1.00 19.93 ? 37 ASN C C 1 ATOM 3493 O O . ASN C 1 56 ? 4.947 18.827 -45.891 1.00 22.26 ? 37 ASN C O 1 ATOM 3494 C CB . ASN C 1 56 ? 7.138 18.376 -43.525 1.00 26.52 ? 37 ASN C CB 1 ATOM 3495 C CG . ASN C 1 56 ? 7.572 17.072 -42.833 1.00 31.89 ? 37 ASN C CG 1 ATOM 3496 O OD1 . ASN C 1 56 ? 7.083 15.978 -43.151 1.00 23.85 ? 37 ASN C OD1 1 ATOM 3497 N ND2 . ASN C 1 56 ? 8.498 17.194 -41.878 1.00 34.87 ? 37 ASN C ND2 1 ATOM 3498 N N . ILE C 1 57 ? 5.300 16.665 -45.414 1.00 28.52 ? 38 ILE C N 1 ATOM 3499 C CA . ILE C 1 57 ? 3.909 16.245 -45.611 1.00 22.23 ? 38 ILE C CA 1 ATOM 3500 C C . ILE C 1 57 ? 3.489 15.443 -44.390 1.00 21.48 ? 38 ILE C C 1 ATOM 3501 O O . ILE C 1 57 ? 4.153 14.486 -44.024 1.00 28.39 ? 38 ILE C O 1 ATOM 3502 C CB . ILE C 1 57 ? 3.739 15.455 -46.898 1.00 16.48 ? 38 ILE C CB 1 ATOM 3503 C CG1 . ILE C 1 57 ? 4.103 16.361 -48.079 1.00 16.01 ? 38 ILE C CG1 1 ATOM 3504 C CG2 . ILE C 1 57 ? 2.313 14.968 -47.014 1.00 20.70 ? 38 ILE C CG2 1 ATOM 3505 C CD1 . ILE C 1 57 ? 4.073 15.717 -49.419 1.00 18.42 ? 38 ILE C CD1 1 ATOM 3506 N N . LEU C 1 58 ? 2.414 15.855 -43.729 1.00 27.14 ? 39 LEU C N 1 ATOM 3507 C CA . LEU C 1 58 ? 2.236 15.458 -42.332 1.00 34.54 ? 39 LEU C CA 1 ATOM 3508 C C . LEU C 1 58 ? 1.072 14.545 -42.053 1.00 42.18 ? 39 LEU C C 1 ATOM 3509 O O . LEU C 1 58 ? 1.226 13.539 -41.365 1.00 56.51 ? 39 LEU C O 1 ATOM 3510 C CB . LEU C 1 58 ? 2.112 16.680 -41.424 1.00 33.04 ? 39 LEU C CB 1 ATOM 3511 C CG . LEU C 1 58 ? 3.393 17.458 -41.220 1.00 32.44 ? 39 LEU C CG 1 ATOM 3512 C CD1 . LEU C 1 58 ? 3.117 18.625 -40.319 1.00 38.58 ? 39 LEU C CD1 1 ATOM 3513 C CD2 . LEU C 1 58 ? 4.442 16.555 -40.621 1.00 34.50 ? 39 LEU C CD2 1 ATOM 3514 N N . GLU C 1 59 ? -0.107 14.908 -42.530 1.00 35.90 ? 40 GLU C N 1 ATOM 3515 C CA . GLU C 1 59 ? -1.269 14.108 -42.197 1.00 32.73 ? 40 GLU C CA 1 ATOM 3516 C C . GLU C 1 59 ? -2.133 13.943 -43.396 1.00 40.29 ? 40 GLU C C 1 ATOM 3517 O O . GLU C 1 59 ? -2.852 14.856 -43.792 1.00 53.30 ? 40 GLU C O 1 ATOM 3518 C CB . GLU C 1 59 ? -2.057 14.721 -41.056 1.00 35.94 ? 40 GLU C CB 1 ATOM 3519 C CG . GLU C 1 59 ? -1.926 13.931 -39.776 1.00 51.80 ? 40 GLU C CG 1 ATOM 3520 C CD . GLU C 1 59 ? -1.988 14.800 -38.537 1.00 72.13 ? 40 GLU C CD 1 ATOM 3521 O OE1 . GLU C 1 59 ? -2.054 16.047 -38.682 1.00 72.87 ? 40 GLU C OE1 1 ATOM 3522 O OE2 . GLU C 1 59 ? -1.970 14.229 -37.418 1.00 75.15 ? 40 GLU C OE2 1 ATOM 3523 N N . VAL C 1 60 ? -2.054 12.767 -43.991 1.00 36.96 ? 41 VAL C N 1 ATOM 3524 C CA . VAL C 1 60 ? -2.815 12.511 -45.189 1.00 29.16 ? 41 VAL C CA 1 ATOM 3525 C C . VAL C 1 60 ? -4.031 11.683 -44.834 1.00 26.65 ? 41 VAL C C 1 ATOM 3526 O O . VAL C 1 60 ? -3.960 10.785 -44.002 1.00 29.56 ? 41 VAL C O 1 ATOM 3527 C CB . VAL C 1 60 ? -1.931 11.826 -46.223 1.00 31.84 ? 41 VAL C CB 1 ATOM 3528 C CG1 . VAL C 1 60 ? -2.736 11.405 -47.395 1.00 32.73 ? 41 VAL C CG1 1 ATOM 3529 C CG2 . VAL C 1 60 ? -0.833 12.784 -46.664 1.00 36.69 ? 41 VAL C CG2 1 ATOM 3530 N N . ASN C 1 61 ? -5.164 12.030 -45.421 1.00 30.77 ? 42 ASN C N 1 ATOM 3531 C CA . ASN C 1 61 ? -6.376 11.238 -45.261 1.00 32.62 ? 42 ASN C CA 1 ATOM 3532 C C . ASN C 1 61 ? -7.008 10.997 -46.627 1.00 38.61 ? 42 ASN C C 1 ATOM 3533 O O . ASN C 1 61 ? -7.605 11.913 -47.211 1.00 38.78 ? 42 ASN C O 1 ATOM 3534 C CB . ASN C 1 61 ? -7.357 11.942 -44.315 1.00 33.88 ? 42 ASN C CB 1 ATOM 3535 C CG . ASN C 1 61 ? -8.573 11.071 -43.955 1.00 36.72 ? 42 ASN C CG 1 ATOM 3536 O OD1 . ASN C 1 61 ? -9.097 10.324 -44.792 1.00 40.23 ? 42 ASN C OD1 1 ATOM 3537 N ND2 . ASN C 1 61 ? -9.026 11.172 -42.704 1.00 28.63 ? 42 ASN C ND2 1 ATOM 3538 N N . GLU C 1 62 ? -6.869 9.769 -47.133 1.00 39.80 ? 43 GLU C N 1 ATOM 3539 C CA . GLU C 1 62 ? -7.368 9.424 -48.469 1.00 37.46 ? 43 GLU C CA 1 ATOM 3540 C C . GLU C 1 62 ? -8.902 9.389 -48.463 1.00 35.42 ? 43 GLU C C 1 ATOM 3541 O O . GLU C 1 62 ? -9.535 9.671 -49.482 1.00 37.04 ? 43 GLU C O 1 ATOM 3542 C CB . GLU C 1 62 ? -6.763 8.091 -48.961 1.00 44.74 ? 43 GLU C CB 1 ATOM 3543 C CG . GLU C 1 62 ? -6.806 7.867 -50.492 1.00 49.76 ? 43 GLU C CG 1 ATOM 3544 C CD . GLU C 1 62 ? -6.131 6.549 -50.955 1.00 57.45 ? 43 GLU C CD 1 ATOM 3545 O OE1 . GLU C 1 62 ? -5.421 5.903 -50.138 1.00 53.44 ? 43 GLU C OE1 1 ATOM 3546 O OE2 . GLU C 1 62 ? -6.314 6.169 -52.143 1.00 50.00 ? 43 GLU C OE2 1 ATOM 3547 N N . ILE C 1 63 ? -9.486 9.083 -47.304 1.00 31.69 ? 44 ILE C N 1 ATOM 3548 C CA . ILE C 1 63 ? -10.941 9.015 -47.174 1.00 36.36 ? 44 ILE C CA 1 ATOM 3549 C C . ILE C 1 63 ? -11.583 10.382 -47.366 1.00 36.19 ? 44 ILE C C 1 ATOM 3550 O O . ILE C 1 63 ? -12.574 10.505 -48.076 1.00 40.79 ? 44 ILE C O 1 ATOM 3551 C CB . ILE C 1 63 ? -11.422 8.477 -45.788 1.00 39.28 ? 44 ILE C CB 1 ATOM 3552 C CG1 . ILE C 1 63 ? -10.828 7.097 -45.462 1.00 48.40 ? 44 ILE C CG1 1 ATOM 3553 C CG2 . ILE C 1 63 ? -12.942 8.449 -45.733 1.00 36.47 ? 44 ILE C CG2 1 ATOM 3554 C CD1 . ILE C 1 63 ? -11.262 5.974 -46.395 1.00 37.97 ? 44 ILE C CD1 1 ATOM 3555 N N . THR C 1 64 ? -11.031 11.405 -46.715 1.00 38.38 ? 45 THR C N 1 ATOM 3556 C CA . THR C 1 64 ? -11.647 12.740 -46.718 1.00 37.61 ? 45 THR C CA 1 ATOM 3557 C C . THR C 1 64 ? -10.973 13.680 -47.694 1.00 31.22 ? 45 THR C C 1 ATOM 3558 O O . THR C 1 64 ? -11.395 14.818 -47.843 1.00 30.55 ? 45 THR C O 1 ATOM 3559 C CB . THR C 1 64 ? -11.575 13.433 -45.349 1.00 31.55 ? 45 THR C CB 1 ATOM 3560 O OG1 . THR C 1 64 ? -10.211 13.763 -45.063 1.00 37.74 ? 45 THR C OG1 1 ATOM 3561 C CG2 . THR C 1 64 ? -12.127 12.556 -44.253 1.00 25.40 ? 45 THR C CG2 1 ATOM 3562 N N . ASN C 1 65 ? -9.914 13.208 -48.334 1.00 31.89 ? 46 ASN C N 1 ATOM 3563 C CA . ASN C 1 65 ? -9.183 14.015 -49.304 1.00 33.63 ? 46 ASN C CA 1 ATOM 3564 C C . ASN C 1 65 ? -8.636 15.314 -48.725 1.00 37.38 ? 46 ASN C C 1 ATOM 3565 O O . ASN C 1 65 ? -8.935 16.402 -49.231 1.00 36.58 ? 46 ASN C O 1 ATOM 3566 C CB . ASN C 1 65 ? -10.041 14.320 -50.542 1.00 38.94 ? 46 ASN C CB 1 ATOM 3567 C CG . ASN C 1 65 ? -9.887 13.286 -51.638 1.00 33.46 ? 46 ASN C CG 1 ATOM 3568 O OD1 . ASN C 1 65 ? -8.920 12.511 -51.668 1.00 35.78 ? 46 ASN C OD1 1 ATOM 3569 N ND2 . ASN C 1 65 ? -10.845 13.277 -52.556 1.00 30.18 ? 46 ASN C ND2 1 ATOM 3570 N N . GLU C 1 66 ? -7.830 15.181 -47.669 1.00 42.69 ? 47 GLU C N 1 ATOM 3571 C CA . GLU C 1 66 ? -7.200 16.315 -46.987 1.00 32.73 ? 47 GLU C CA 1 ATOM 3572 C C . GLU C 1 66 ? -5.735 16.038 -46.701 1.00 35.89 ? 47 GLU C C 1 ATOM 3573 O O . GLU C 1 66 ? -5.379 14.934 -46.287 1.00 40.02 ? 47 GLU C O 1 ATOM 3574 C CB . GLU C 1 66 ? -7.924 16.599 -45.677 1.00 30.18 ? 47 GLU C CB 1 ATOM 3575 C CG . GLU C 1 66 ? -9.360 16.991 -45.877 1.00 43.13 ? 47 GLU C CG 1 ATOM 3576 C CD . GLU C 1 66 ? -10.104 17.227 -44.571 1.00 60.36 ? 47 GLU C CD 1 ATOM 3577 O OE1 . GLU C 1 66 ? -9.437 17.288 -43.507 1.00 56.79 ? 47 GLU C OE1 1 ATOM 3578 O OE2 . GLU C 1 66 ? -11.359 17.350 -44.622 1.00 63.12 ? 47 GLU C OE2 1 ATOM 3579 N N . VAL C 1 67 ? -4.882 17.037 -46.911 1.00 38.57 ? 48 VAL C N 1 ATOM 3580 C CA . VAL C 1 67 ? -3.463 16.894 -46.573 1.00 38.53 ? 48 VAL C CA 1 ATOM 3581 C C . VAL C 1 67 ? -2.979 18.032 -45.690 1.00 38.49 ? 48 VAL C C 1 ATOM 3582 O O . VAL C 1 67 ? -3.555 19.125 -45.693 1.00 37.02 ? 48 VAL C O 1 ATOM 3583 C CB . VAL C 1 67 ? -2.579 16.829 -47.828 1.00 33.76 ? 48 VAL C CB 1 ATOM 3584 C CG1 . VAL C 1 67 ? -3.001 15.689 -48.704 1.00 35.99 ? 48 VAL C CG1 1 ATOM 3585 C CG2 . VAL C 1 67 ? -2.682 18.133 -48.601 1.00 38.01 ? 48 VAL C CG2 1 ATOM 3586 N N . ASP C 1 68 ? -1.905 17.766 -44.952 1.00 39.33 ? 49 ASP C N 1 ATOM 3587 C CA . ASP C 1 68 ? -1.249 18.774 -44.115 1.00 33.93 ? 49 ASP C CA 1 ATOM 3588 C C . ASP C 1 68 ? 0.149 19.057 -44.629 1.00 27.55 ? 49 ASP C C 1 ATOM 3589 O O . ASP C 1 68 ? 1.034 18.197 -44.567 1.00 29.25 ? 49 ASP C O 1 ATOM 3590 C CB . ASP C 1 68 ? -1.115 18.244 -42.702 1.00 39.05 ? 49 ASP C CB 1 ATOM 3591 C CG . ASP C 1 68 ? -1.651 19.188 -41.699 1.00 42.94 ? 49 ASP C CG 1 ATOM 3592 O OD1 . ASP C 1 68 ? -2.511 20.004 -42.101 1.00 54.62 ? 49 ASP C OD1 1 ATOM 3593 O OD2 . ASP C 1 68 ? -1.228 19.117 -40.522 1.00 50.09 ? 49 ASP C OD2 1 ATOM 3594 N N . VAL C 1 69 ? 0.370 20.257 -45.129 1.00 24.47 ? 50 VAL C N 1 ATOM 3595 C CA . VAL C 1 69 ? 1.659 20.550 -45.734 1.00 22.77 ? 50 VAL C CA 1 ATOM 3596 C C . VAL C 1 69 ? 2.437 21.614 -44.963 1.00 19.97 ? 50 VAL C C 1 ATOM 3597 O O . VAL C 1 69 ? 1.844 22.527 -44.401 1.00 23.08 ? 50 VAL C O 1 ATOM 3598 C CB . VAL C 1 69 ? 1.468 20.955 -47.201 1.00 22.64 ? 50 VAL C CB 1 ATOM 3599 C CG1 . VAL C 1 69 ? 2.811 21.167 -47.889 1.00 24.25 ? 50 VAL C CG1 1 ATOM 3600 C CG2 . VAL C 1 69 ? 0.696 19.866 -47.916 1.00 29.71 ? 50 VAL C CG2 1 ATOM 3601 N N . VAL C 1 70 ? 3.760 21.460 -44.904 1.00 20.44 ? 51 VAL C N 1 ATOM 3602 C CA . VAL C 1 70 ? 4.664 22.532 -44.477 1.00 17.76 ? 51 VAL C CA 1 ATOM 3603 C C . VAL C 1 70 ? 5.543 22.926 -45.654 1.00 18.41 ? 51 VAL C C 1 ATOM 3604 O O . VAL C 1 70 ? 6.237 22.089 -46.229 1.00 20.32 ? 51 VAL C O 1 ATOM 3605 C CB . VAL C 1 70 ? 5.574 22.122 -43.316 1.00 14.73 ? 51 VAL C CB 1 ATOM 3606 C CG1 . VAL C 1 70 ? 6.604 23.197 -43.095 1.00 13.69 ? 51 VAL C CG1 1 ATOM 3607 C CG2 . VAL C 1 70 ? 4.766 21.884 -42.045 1.00 16.01 ? 51 VAL C CG2 1 ATOM 3608 N N . PHE C 1 71 ? 5.515 24.205 -46.007 1.00 21.05 ? 52 PHE C N 1 ATOM 3609 C CA . PHE C 1 71 ? 6.258 24.709 -47.162 1.00 20.99 ? 52 PHE C CA 1 ATOM 3610 C C . PHE C 1 71 ? 6.739 26.140 -46.936 1.00 22.11 ? 52 PHE C C 1 ATOM 3611 O O . PHE C 1 71 ? 6.153 26.871 -46.135 1.00 25.58 ? 52 PHE C O 1 ATOM 3612 C CB . PHE C 1 71 ? 5.355 24.673 -48.393 1.00 24.28 ? 52 PHE C CB 1 ATOM 3613 C CG . PHE C 1 71 ? 4.068 25.454 -48.229 1.00 26.69 ? 52 PHE C CG 1 ATOM 3614 C CD1 . PHE C 1 71 ? 2.969 24.886 -47.587 1.00 22.98 ? 52 PHE C CD1 1 ATOM 3615 C CD2 . PHE C 1 71 ? 3.963 26.760 -48.713 1.00 24.49 ? 52 PHE C CD2 1 ATOM 3616 C CE1 . PHE C 1 71 ? 1.788 25.601 -47.438 1.00 28.49 ? 52 PHE C CE1 1 ATOM 3617 C CE2 . PHE C 1 71 ? 2.794 27.489 -48.561 1.00 22.84 ? 52 PHE C CE2 1 ATOM 3618 C CZ . PHE C 1 71 ? 1.702 26.911 -47.927 1.00 30.50 ? 52 PHE C CZ 1 ATOM 3619 N N . TRP C 1 72 ? 7.799 26.542 -47.635 1.00 21.87 ? 53 TRP C N 1 ATOM 3620 C CA . TRP C 1 72 ? 8.194 27.956 -47.659 1.00 21.69 ? 53 TRP C CA 1 ATOM 3621 C C . TRP C 1 72 ? 7.451 28.599 -48.801 1.00 22.54 ? 53 TRP C C 1 ATOM 3622 O O . TRP C 1 72 ? 7.412 28.047 -49.895 1.00 20.44 ? 53 TRP C O 1 ATOM 3623 C CB . TRP C 1 72 ? 9.692 28.137 -47.910 1.00 22.16 ? 53 TRP C CB 1 ATOM 3624 C CG . TRP C 1 72 ? 10.589 27.545 -46.862 1.00 21.21 ? 53 TRP C CG 1 ATOM 3625 C CD1 . TRP C 1 72 ? 10.209 26.889 -45.726 1.00 19.18 ? 53 TRP C CD1 1 ATOM 3626 C CD2 . TRP C 1 72 ? 12.025 27.546 -46.868 1.00 19.20 ? 53 TRP C CD2 1 ATOM 3627 N NE1 . TRP C 1 72 ? 11.316 26.489 -45.021 1.00 15.59 ? 53 TRP C NE1 1 ATOM 3628 C CE2 . TRP C 1 72 ? 12.442 26.880 -45.694 1.00 16.36 ? 53 TRP C CE2 1 ATOM 3629 C CE3 . TRP C 1 72 ? 12.997 28.058 -47.745 1.00 19.62 ? 53 TRP C CE3 1 ATOM 3630 C CZ2 . TRP C 1 72 ? 13.791 26.704 -45.377 1.00 16.99 ? 53 TRP C CZ2 1 ATOM 3631 C CZ3 . TRP C 1 72 ? 14.337 27.893 -47.427 1.00 19.94 ? 53 TRP C CZ3 1 ATOM 3632 C CH2 . TRP C 1 72 ? 14.721 27.212 -46.258 1.00 23.15 ? 53 TRP C CH2 1 ATOM 3633 N N . GLN C 1 73 ? 6.859 29.763 -48.554 1.00 25.72 ? 54 GLN C N 1 ATOM 3634 C CA . GLN C 1 73 ? 6.150 30.480 -49.609 1.00 24.04 ? 54 GLN C CA 1 ATOM 3635 C C . GLN C 1 73 ? 6.960 31.684 -50.057 1.00 25.71 ? 54 GLN C C 1 ATOM 3636 O O . GLN C 1 73 ? 6.757 32.806 -49.578 1.00 24.63 ? 54 GLN C O 1 ATOM 3637 C CB . GLN C 1 73 ? 4.776 30.917 -49.119 1.00 27.63 ? 54 GLN C CB 1 ATOM 3638 C CG . GLN C 1 73 ? 3.962 31.637 -50.164 1.00 26.36 ? 54 GLN C CG 1 ATOM 3639 C CD . GLN C 1 73 ? 2.551 31.906 -49.710 1.00 29.16 ? 54 GLN C CD 1 ATOM 3640 O OE1 . GLN C 1 73 ? 1.814 30.989 -49.341 1.00 26.46 ? 54 GLN C OE1 1 ATOM 3641 N NE2 . GLN C 1 73 ? 2.165 33.179 -49.729 1.00 46.34 ? 54 GLN C NE2 1 ATOM 3642 N N . GLN C 1 74 ? 7.891 31.452 -50.978 1.00 25.51 ? 55 GLN C N 1 ATOM 3643 C CA . GLN C 1 74 ? 8.804 32.509 -51.394 1.00 26.47 ? 55 GLN C CA 1 ATOM 3644 C C . GLN C 1 74 ? 8.118 33.516 -52.324 1.00 28.93 ? 55 GLN C C 1 ATOM 3645 O O . GLN C 1 74 ? 7.722 33.181 -53.439 1.00 29.28 ? 55 GLN C O 1 ATOM 3646 C CB . GLN C 1 74 ? 10.020 31.907 -52.071 1.00 28.90 ? 55 GLN C CB 1 ATOM 3647 C CG . GLN C 1 74 ? 10.969 32.956 -52.621 1.00 43.25 ? 55 GLN C CG 1 ATOM 3648 C CD . GLN C 1 74 ? 12.215 32.344 -53.248 1.00 48.93 ? 55 GLN C CD 1 ATOM 3649 O OE1 . GLN C 1 74 ? 12.745 31.338 -52.764 1.00 58.52 ? 55 GLN C OE1 1 ATOM 3650 N NE2 . GLN C 1 74 ? 12.686 32.950 -54.329 1.00 46.48 ? 55 GLN C NE2 1 ATOM 3651 N N . THR C 1 75 ? 7.981 34.753 -51.858 1.00 27.12 ? 56 THR C N 1 ATOM 3652 C CA . THR C 1 75 ? 7.202 35.771 -52.569 1.00 22.48 ? 56 THR C CA 1 ATOM 3653 C C . THR C 1 75 ? 8.093 36.975 -52.867 1.00 26.11 ? 56 THR C C 1 ATOM 3654 O O . THR C 1 75 ? 8.790 37.478 -51.970 1.00 24.20 ? 56 THR C O 1 ATOM 3655 C CB . THR C 1 75 ? 6.005 36.252 -51.719 1.00 20.21 ? 56 THR C CB 1 ATOM 3656 O OG1 . THR C 1 75 ? 5.304 35.130 -51.161 1.00 26.85 ? 56 THR C OG1 1 ATOM 3657 C CG2 . THR C 1 75 ? 5.049 37.048 -52.552 1.00 20.98 ? 56 THR C CG2 1 ATOM 3658 N N . THR C 1 76 ? 8.069 37.444 -54.115 1.00 22.23 ? 57 THR C N 1 ATOM 3659 C CA . THR C 1 76 ? 8.997 38.496 -54.543 1.00 22.37 ? 57 THR C CA 1 ATOM 3660 C C . THR C 1 76 ? 8.335 39.579 -55.410 1.00 24.75 ? 57 THR C C 1 ATOM 3661 O O . THR C 1 76 ? 7.588 39.273 -56.331 1.00 25.39 ? 57 THR C O 1 ATOM 3662 C CB . THR C 1 76 ? 10.229 37.875 -55.258 1.00 25.11 ? 57 THR C CB 1 ATOM 3663 O OG1 . THR C 1 76 ? 11.015 37.150 -54.299 1.00 27.89 ? 57 THR C OG1 1 ATOM 3664 C CG2 . THR C 1 76 ? 11.118 38.953 -55.907 1.00 37.11 ? 57 THR C CG2 1 ATOM 3665 N N . TRP C 1 77 ? 8.601 40.846 -55.109 1.00 20.98 ? 58 TRP C N 1 ATOM 3666 C CA . TRP C 1 77 ? 8.039 41.921 -55.910 1.00 22.70 ? 58 TRP C CA 1 ATOM 3667 C C . TRP C 1 77 ? 8.876 43.171 -55.794 1.00 22.74 ? 58 TRP C C 1 ATOM 3668 O O . TRP C 1 77 ? 9.847 43.216 -55.049 1.00 25.97 ? 58 TRP C O 1 ATOM 3669 C CB . TRP C 1 77 ? 6.602 42.228 -55.482 1.00 22.48 ? 58 TRP C CB 1 ATOM 3670 C CG . TRP C 1 77 ? 6.536 42.846 -54.125 1.00 22.36 ? 58 TRP C CG 1 ATOM 3671 C CD1 . TRP C 1 77 ? 6.501 44.178 -53.831 1.00 24.37 ? 58 TRP C CD1 1 ATOM 3672 C CD2 . TRP C 1 77 ? 6.524 42.158 -52.874 1.00 18.19 ? 58 TRP C CD2 1 ATOM 3673 N NE1 . TRP C 1 77 ? 6.459 44.361 -52.475 1.00 22.04 ? 58 TRP C NE1 1 ATOM 3674 C CE2 . TRP C 1 77 ? 6.468 43.135 -51.860 1.00 18.77 ? 58 TRP C CE2 1 ATOM 3675 C CE3 . TRP C 1 77 ? 6.536 40.811 -52.514 1.00 19.85 ? 58 TRP C CE3 1 ATOM 3676 C CZ2 . TRP C 1 77 ? 6.434 42.810 -50.498 1.00 16.90 ? 58 TRP C CZ2 1 ATOM 3677 C CZ3 . TRP C 1 77 ? 6.499 40.486 -51.157 1.00 27.14 ? 58 TRP C CZ3 1 ATOM 3678 C CH2 . TRP C 1 77 ? 6.454 41.490 -50.162 1.00 18.45 ? 58 TRP C CH2 1 ATOM 3679 N N . SER C 1 78 ? 8.478 44.207 -56.516 1.00 26.33 ? 59 SER C N 1 ATOM 3680 C CA . SER C 1 78 ? 9.240 45.456 -56.506 1.00 32.54 ? 59 SER C CA 1 ATOM 3681 C C . SER C 1 78 ? 8.452 46.659 -55.964 1.00 26.77 ? 59 SER C C 1 ATOM 3682 O O . SER C 1 78 ? 7.291 46.874 -56.321 1.00 33.04 ? 59 SER C O 1 ATOM 3683 C CB . SER C 1 78 ? 9.776 45.746 -57.904 1.00 37.84 ? 59 SER C CB 1 ATOM 3684 O OG . SER C 1 78 ? 10.503 46.953 -57.914 1.00 47.37 ? 59 SER C OG 1 ATOM 3685 N N . ASP C 1 79 ? 9.091 47.433 -55.093 1.00 25.26 ? 60 ASP C N 1 ATOM 3686 C CA . ASP C 1 79 ? 8.481 48.631 -54.515 1.00 29.07 ? 60 ASP C CA 1 ATOM 3687 C C . ASP C 1 79 ? 9.491 49.781 -54.461 1.00 31.17 ? 60 ASP C C 1 ATOM 3688 O O . ASP C 1 79 ? 10.247 49.892 -53.494 1.00 29.63 ? 60 ASP C O 1 ATOM 3689 C CB . ASP C 1 79 ? 7.956 48.336 -53.102 1.00 35.89 ? 60 ASP C CB 1 ATOM 3690 C CG . ASP C 1 79 ? 7.004 49.434 -52.565 1.00 40.08 ? 60 ASP C CG 1 ATOM 3691 O OD1 . ASP C 1 79 ? 7.103 50.615 -52.997 1.00 27.56 ? 60 ASP C OD1 1 ATOM 3692 O OD2 . ASP C 1 79 ? 6.147 49.105 -51.702 1.00 36.09 ? 60 ASP C OD2 1 ATOM 3693 N N . ARG C 1 80 ? 9.476 50.638 -55.488 1.00 32.09 ? 61 ARG C N 1 ATOM 3694 C CA . ARG C 1 80 ? 10.451 51.733 -55.639 1.00 38.39 ? 61 ARG C CA 1 ATOM 3695 C C . ARG C 1 80 ? 10.393 52.768 -54.501 1.00 36.01 ? 61 ARG C C 1 ATOM 3696 O O . ARG C 1 80 ? 11.369 53.470 -54.227 1.00 39.42 ? 61 ARG C O 1 ATOM 3697 C CB . ARG C 1 80 ? 10.296 52.441 -57.003 1.00 43.67 ? 61 ARG C CB 1 ATOM 3698 C CG . ARG C 1 80 ? 10.237 51.505 -58.215 1.00 66.00 ? 61 ARG C CG 1 ATOM 3699 C CD . ARG C 1 80 ? 11.601 50.943 -58.654 1.00 62.31 ? 61 ARG C CD 1 ATOM 3700 N NE . ARG C 1 80 ? 11.492 50.244 -59.943 1.00 73.61 ? 61 ARG C NE 1 ATOM 3701 C CZ . ARG C 1 80 ? 11.896 48.992 -60.177 1.00 83.93 ? 61 ARG C CZ 1 ATOM 3702 N NH1 . ARG C 1 80 ? 12.465 48.273 -59.212 1.00 84.21 ? 61 ARG C NH1 1 ATOM 3703 N NH2 . ARG C 1 80 ? 11.740 48.459 -61.387 1.00 75.64 ? 61 ARG C NH2 1 ATOM 3704 N N . THR C 1 81 ? 9.244 52.860 -53.848 1.00 31.05 ? 62 THR C N 1 ATOM 3705 C CA . THR C 1 81 ? 9.081 53.694 -52.659 1.00 29.76 ? 62 THR C CA 1 ATOM 3706 C C . THR C 1 81 ? 10.138 53.393 -51.582 1.00 29.88 ? 62 THR C C 1 ATOM 3707 O O . THR C 1 81 ? 10.498 54.261 -50.800 1.00 28.24 ? 62 THR C O 1 ATOM 3708 C CB . THR C 1 81 ? 7.658 53.503 -52.072 1.00 36.88 ? 62 THR C CB 1 ATOM 3709 O OG1 . THR C 1 81 ? 6.684 53.816 -53.077 1.00 41.54 ? 62 THR C OG1 1 ATOM 3710 C CG2 . THR C 1 81 ? 7.406 54.386 -50.853 1.00 38.58 ? 62 THR C CG2 1 ATOM 3711 N N . LEU C 1 82 ? 10.648 52.166 -51.552 1.00 28.87 ? 63 LEU C N 1 ATOM 3712 C CA . LEU C 1 82 ? 11.575 51.760 -50.504 1.00 23.85 ? 63 LEU C CA 1 ATOM 3713 C C . LEU C 1 82 ? 13.034 51.986 -50.874 1.00 29.20 ? 63 LEU C C 1 ATOM 3714 O O . LEU C 1 82 ? 13.928 51.780 -50.048 1.00 31.11 ? 63 LEU C O 1 ATOM 3715 C CB . LEU C 1 82 ? 11.373 50.283 -50.175 1.00 24.57 ? 63 LEU C CB 1 ATOM 3716 C CG . LEU C 1 82 ? 9.953 49.854 -49.825 1.00 20.70 ? 63 LEU C CG 1 ATOM 3717 C CD1 . LEU C 1 82 ? 9.854 48.364 -49.884 1.00 17.59 ? 63 LEU C CD1 1 ATOM 3718 C CD2 . LEU C 1 82 ? 9.606 50.346 -48.444 1.00 24.14 ? 63 LEU C CD2 1 ATOM 3719 N N . ALA C 1 83 ? 13.288 52.404 -52.108 1.00 28.09 ? 64 ALA C N 1 ATOM 3720 C CA . ALA C 1 83 ? 14.662 52.440 -52.609 1.00 28.58 ? 64 ALA C CA 1 ATOM 3721 C C . ALA C 1 83 ? 15.498 53.510 -51.914 1.00 30.28 ? 64 ALA C C 1 ATOM 3722 O O . ALA C 1 83 ? 14.950 54.503 -51.413 1.00 30.32 ? 64 ALA C O 1 ATOM 3723 C CB . ALA C 1 83 ? 14.678 52.634 -54.119 1.00 25.95 ? 64 ALA C CB 1 ATOM 3724 N N . TRP C 1 84 ? 16.817 53.295 -51.878 1.00 27.49 ? 65 TRP C N 1 ATOM 3725 C CA . TRP C 1 84 ? 17.763 54.308 -51.384 1.00 35.74 ? 65 TRP C CA 1 ATOM 3726 C C . TRP C 1 84 ? 19.093 54.271 -52.144 1.00 37.06 ? 65 TRP C C 1 ATOM 3727 O O . TRP C 1 84 ? 19.381 53.287 -52.837 1.00 40.94 ? 65 TRP C O 1 ATOM 3728 C CB . TRP C 1 84 ? 17.997 54.150 -49.875 1.00 28.02 ? 65 TRP C CB 1 ATOM 3729 C CG . TRP C 1 84 ? 18.751 52.919 -49.482 1.00 29.49 ? 65 TRP C CG 1 ATOM 3730 C CD1 . TRP C 1 84 ? 20.106 52.796 -49.329 1.00 33.25 ? 65 TRP C CD1 1 ATOM 3731 C CD2 . TRP C 1 84 ? 18.196 51.635 -49.170 1.00 32.55 ? 65 TRP C CD2 1 ATOM 3732 N NE1 . TRP C 1 84 ? 20.429 51.514 -48.946 1.00 25.20 ? 65 TRP C NE1 1 ATOM 3733 C CE2 . TRP C 1 84 ? 19.274 50.779 -48.837 1.00 29.12 ? 65 TRP C CE2 1 ATOM 3734 C CE3 . TRP C 1 84 ? 16.890 51.119 -49.143 1.00 28.99 ? 65 TRP C CE3 1 ATOM 3735 C CZ2 . TRP C 1 84 ? 19.089 49.432 -48.485 1.00 27.00 ? 65 TRP C CZ2 1 ATOM 3736 C CZ3 . TRP C 1 84 ? 16.708 49.780 -48.799 1.00 22.35 ? 65 TRP C CZ3 1 ATOM 3737 C CH2 . TRP C 1 84 ? 17.805 48.953 -48.476 1.00 22.09 ? 65 TRP C CH2 1 ATOM 3738 N N . ASN C 1 85 ? 19.940 55.245 -51.916 1.00 38.26 ? 66 ASN C N 1 ATOM 3739 C CA . ASN C 1 85 ? 21.269 55.222 -52.464 1.00 47.31 ? 66 ASN C CA 1 ATOM 3740 C C . ASN C 1 85 ? 22.193 54.339 -51.656 1.00 47.53 ? 66 ASN C C 1 ATOM 3741 O O . ASN C 1 85 ? 22.374 54.553 -50.492 1.00 50.66 ? 66 ASN C O 1 ATOM 3742 C CB . ASN C 1 85 ? 21.801 56.637 -52.448 1.00 44.31 ? 66 ASN C CB 1 ATOM 3743 C CG . ASN C 1 85 ? 22.923 56.839 -53.398 1.00 51.70 ? 66 ASN C CG 1 ATOM 3744 O OD1 . ASN C 1 85 ? 23.602 55.913 -53.754 1.00 53.21 ? 66 ASN C OD1 1 ATOM 3745 N ND2 . ASN C 1 85 ? 23.118 58.057 -53.818 1.00 60.96 ? 66 ASN C ND2 1 ATOM 3746 N N . SER C 1 86 ? 22.818 53.371 -52.292 1.00 44.25 ? 67 SER C N 1 ATOM 3747 C CA . SER C 1 86 ? 23.583 52.390 -51.576 1.00 46.91 ? 67 SER C CA 1 ATOM 3748 C C . SER C 1 86 ? 25.022 52.708 -51.603 1.00 54.95 ? 67 SER C C 1 ATOM 3749 O O . SER C 1 86 ? 25.834 51.880 -51.299 1.00 54.65 ? 67 SER C O 1 ATOM 3750 C CB . SER C 1 86 ? 23.365 51.001 -52.146 1.00 54.75 ? 67 SER C CB 1 ATOM 3751 O OG . SER C 1 86 ? 24.219 50.699 -53.219 1.00 53.37 ? 67 SER C OG 1 ATOM 3752 N N . SER C 1 87 ? 25.343 53.912 -52.015 1.00 59.29 ? 68 SER C N 1 ATOM 3753 C CA . SER C 1 87 ? 26.668 54.215 -52.447 1.00 58.11 ? 68 SER C CA 1 ATOM 3754 C C . SER C 1 87 ? 27.732 54.038 -51.415 1.00 61.66 ? 68 SER C C 1 ATOM 3755 O O . SER C 1 87 ? 28.747 53.463 -51.721 1.00 72.52 ? 68 SER C O 1 ATOM 3756 C CB . SER C 1 87 ? 26.715 55.617 -52.987 1.00 58.38 ? 68 SER C CB 1 ATOM 3757 O OG . SER C 1 87 ? 28.034 55.947 -53.306 1.00 67.33 ? 68 SER C OG 1 ATOM 3758 N N . HIS C 1 88 ? 27.521 54.492 -50.201 1.00 51.81 ? 69 HIS C N 1 ATOM 3759 C CA . HIS C 1 88 ? 28.478 54.235 -49.154 1.00 58.25 ? 69 HIS C CA 1 ATOM 3760 C C . HIS C 1 88 ? 27.700 53.622 -48.019 1.00 61.55 ? 69 HIS C C 1 ATOM 3761 O O . HIS C 1 88 ? 27.933 53.889 -46.869 1.00 64.52 ? 69 HIS C O 1 ATOM 3762 C CB . HIS C 1 88 ? 29.225 55.500 -48.747 1.00 60.91 ? 69 HIS C CB 1 ATOM 3763 C CG . HIS C 1 88 ? 30.134 56.039 -49.811 1.00 81.81 ? 69 HIS C CG 1 ATOM 3764 N ND1 . HIS C 1 88 ? 31.200 55.327 -50.314 1.00 93.79 ? 69 HIS C ND1 1 ATOM 3765 C CD2 . HIS C 1 88 ? 30.136 57.221 -50.469 1.00 80.54 ? 69 HIS C CD2 1 ATOM 3766 C CE1 . HIS C 1 88 ? 31.806 56.036 -51.248 1.00 84.47 ? 69 HIS C CE1 1 ATOM 3767 N NE2 . HIS C 1 88 ? 31.185 57.193 -51.354 1.00 81.40 ? 69 HIS C NE2 1 ATOM 3768 N N . SER C 1 89 ? 26.739 52.802 -48.380 1.00 53.93 ? 70 SER C N 1 ATOM 3769 C CA . SER C 1 89 ? 25.722 52.358 -47.489 1.00 46.57 ? 70 SER C CA 1 ATOM 3770 C C . SER C 1 89 ? 25.485 50.893 -47.538 1.00 49.73 ? 70 SER C C 1 ATOM 3771 O O . SER C 1 89 ? 26.027 50.201 -48.356 1.00 57.02 ? 70 SER C O 1 ATOM 3772 C CB . SER C 1 89 ? 24.438 53.044 -47.829 1.00 51.66 ? 70 SER C CB 1 ATOM 3773 O OG . SER C 1 89 ? 24.627 54.417 -47.757 1.00 59.64 ? 70 SER C OG 1 ATOM 3774 N N . PRO C 1 90 ? 24.651 50.421 -46.546 1.00 44.59 ? 71 PRO C N 1 ATOM 3775 C CA . PRO C 1 90 ? 24.248 49.028 -46.702 1.00 36.11 ? 71 PRO C CA 1 ATOM 3776 C C . PRO C 1 90 ? 23.375 48.882 -47.906 1.00 38.50 ? 71 PRO C C 1 ATOM 3777 O O . PRO C 1 90 ? 22.766 49.827 -48.263 1.00 44.60 ? 71 PRO C O 1 ATOM 3778 C CB . PRO C 1 90 ? 23.424 48.772 -45.467 1.00 38.91 ? 71 PRO C CB 1 ATOM 3779 C CG . PRO C 1 90 ? 23.910 49.717 -44.472 1.00 38.29 ? 71 PRO C CG 1 ATOM 3780 C CD . PRO C 1 90 ? 24.014 50.934 -45.257 1.00 35.57 ? 71 PRO C CD 1 ATOM 3781 N N . ASP C 1 91 ? 23.364 47.750 -48.569 1.00 39.39 ? 72 ASP C N 1 ATOM 3782 C CA . ASP C 1 91 ? 22.505 47.567 -49.714 1.00 39.20 ? 72 ASP C CA 1 ATOM 3783 C C . ASP C 1 91 ? 21.313 46.703 -49.454 1.00 40.00 ? 72 ASP C C 1 ATOM 3784 O O . ASP C 1 91 ? 20.582 46.402 -50.341 1.00 41.90 ? 72 ASP C O 1 ATOM 3785 C CB . ASP C 1 91 ? 23.286 46.971 -50.854 1.00 44.06 ? 72 ASP C CB 1 ATOM 3786 C CG . ASP C 1 91 ? 24.243 45.938 -50.409 1.00 58.47 ? 72 ASP C CG 1 ATOM 3787 O OD1 . ASP C 1 91 ? 24.369 45.683 -49.197 1.00 60.97 ? 72 ASP C OD1 1 ATOM 3788 O OD2 . ASP C 1 91 ? 24.897 45.377 -51.286 1.00 70.65 ? 72 ASP C OD2 1 ATOM 3789 N N . GLN C 1 92 ? 21.145 46.296 -48.220 1.00 39.04 ? 73 GLN C N 1 ATOM 3790 C CA . GLN C 1 92 ? 20.010 45.487 -47.778 1.00 30.79 ? 73 GLN C CA 1 ATOM 3791 C C . GLN C 1 92 ? 19.691 45.669 -46.299 1.00 30.76 ? 73 GLN C C 1 ATOM 3792 O O . GLN C 1 92 ? 20.579 45.951 -45.493 1.00 34.78 ? 73 GLN C O 1 ATOM 3793 C CB . GLN C 1 92 ? 20.322 44.029 -48.007 1.00 31.63 ? 73 GLN C CB 1 ATOM 3794 C CG . GLN C 1 92 ? 21.581 43.626 -47.305 1.00 42.55 ? 73 GLN C CG 1 ATOM 3795 C CD . GLN C 1 92 ? 21.756 42.125 -47.270 1.00 65.38 ? 73 GLN C CD 1 ATOM 3796 O OE1 . GLN C 1 92 ? 21.477 41.427 -48.256 1.00 69.78 ? 73 GLN C OE1 1 ATOM 3797 N NE2 . GLN C 1 92 ? 22.208 41.610 -46.123 1.00 54.07 ? 73 GLN C NE2 1 ATOM 3798 N N . VAL C 1 93 ? 18.418 45.495 -45.946 1.00 26.22 ? 74 VAL C N 1 ATOM 3799 C CA . VAL C 1 93 ? 17.979 45.535 -44.546 1.00 24.58 ? 74 VAL C CA 1 ATOM 3800 C C . VAL C 1 93 ? 16.832 44.550 -44.350 1.00 22.58 ? 74 VAL C C 1 ATOM 3801 O O . VAL C 1 93 ? 16.176 44.171 -45.324 1.00 24.46 ? 74 VAL C O 1 ATOM 3802 C CB . VAL C 1 93 ? 17.518 46.967 -44.110 1.00 25.26 ? 74 VAL C CB 1 ATOM 3803 C CG1 . VAL C 1 93 ? 18.690 47.942 -44.055 1.00 21.96 ? 74 VAL C CG1 1 ATOM 3804 C CG2 . VAL C 1 93 ? 16.431 47.492 -45.037 1.00 20.90 ? 74 VAL C CG2 1 ATOM 3805 N N . SER C 1 94 ? 16.574 44.147 -43.105 1.00 20.55 ? 75 SER C N 1 ATOM 3806 C CA . SER C 1 94 ? 15.379 43.345 -42.793 1.00 17.99 ? 75 SER C CA 1 ATOM 3807 C C . SER C 1 94 ? 14.291 44.226 -42.186 1.00 24.01 ? 75 SER C C 1 ATOM 3808 O O . SER C 1 94 ? 14.560 45.018 -41.280 1.00 25.81 ? 75 SER C O 1 ATOM 3809 C CB . SER C 1 94 ? 15.716 42.195 -41.845 1.00 19.80 ? 75 SER C CB 1 ATOM 3810 O OG . SER C 1 94 ? 16.391 41.155 -42.529 1.00 31.08 ? 75 SER C OG 1 ATOM 3811 N N . VAL C 1 95 ? 13.063 44.092 -42.677 1.00 23.17 ? 76 VAL C N 1 ATOM 3812 C CA . VAL C 1 95 ? 11.998 45.003 -42.285 1.00 18.89 ? 76 VAL C CA 1 ATOM 3813 C C . VAL C 1 95 ? 10.798 44.211 -41.814 1.00 20.35 ? 76 VAL C C 1 ATOM 3814 O O . VAL C 1 95 ? 10.392 43.267 -42.485 1.00 21.31 ? 76 VAL C O 1 ATOM 3815 C CB . VAL C 1 95 ? 11.571 45.873 -43.478 1.00 20.91 ? 76 VAL C CB 1 ATOM 3816 C CG1 . VAL C 1 95 ? 10.448 46.825 -43.090 1.00 23.86 ? 76 VAL C CG1 1 ATOM 3817 C CG2 . VAL C 1 95 ? 12.761 46.634 -44.041 1.00 17.78 ? 76 VAL C CG2 1 ATOM 3818 N N . PRO C 1 96 ? 10.213 44.595 -40.663 1.00 24.12 ? 77 PRO C N 1 ATOM 3819 C CA . PRO C 1 96 ? 8.984 43.911 -40.225 1.00 21.77 ? 77 PRO C CA 1 ATOM 3820 C C . PRO C 1 96 ? 7.872 44.119 -41.263 1.00 20.50 ? 77 PRO C C 1 ATOM 3821 O O . PRO C 1 96 ? 7.679 45.259 -41.699 1.00 21.49 ? 77 PRO C O 1 ATOM 3822 C CB . PRO C 1 96 ? 8.637 44.636 -38.918 1.00 22.94 ? 77 PRO C CB 1 ATOM 3823 C CG . PRO C 1 96 ? 9.920 45.286 -38.479 1.00 18.28 ? 77 PRO C CG 1 ATOM 3824 C CD . PRO C 1 96 ? 10.619 45.668 -39.734 1.00 17.24 ? 77 PRO C CD 1 ATOM 3825 N N . ILE C 1 97 ? 7.164 43.058 -41.660 1.00 19.77 ? 78 ILE C N 1 ATOM 3826 C CA . ILE C 1 97 ? 6.173 43.194 -42.735 1.00 22.44 ? 78 ILE C CA 1 ATOM 3827 C C . ILE C 1 97 ? 5.045 44.181 -42.391 1.00 24.99 ? 78 ILE C C 1 ATOM 3828 O O . ILE C 1 97 ? 4.350 44.687 -43.269 1.00 28.23 ? 78 ILE C O 1 ATOM 3829 C CB . ILE C 1 97 ? 5.560 41.852 -43.188 1.00 16.59 ? 78 ILE C CB 1 ATOM 3830 C CG1 . ILE C 1 97 ? 4.835 41.170 -42.022 1.00 23.97 ? 78 ILE C CG1 1 ATOM 3831 C CG2 . ILE C 1 97 ? 6.608 40.954 -43.789 1.00 16.29 ? 78 ILE C CG2 1 ATOM 3832 C CD1 . ILE C 1 97 ? 4.003 39.963 -42.440 1.00 19.56 ? 78 ILE C CD1 1 ATOM 3833 N N . SER C 1 98 ? 4.854 44.460 -41.112 1.00 27.41 ? 79 SER C N 1 ATOM 3834 C CA . SER C 1 98 ? 3.824 45.417 -40.735 1.00 24.19 ? 79 SER C CA 1 ATOM 3835 C C . SER C 1 98 ? 4.139 46.809 -41.308 1.00 21.75 ? 79 SER C C 1 ATOM 3836 O O . SER C 1 98 ? 3.250 47.654 -41.405 1.00 20.91 ? 79 SER C O 1 ATOM 3837 C CB . SER C 1 98 ? 3.632 45.433 -39.208 1.00 22.22 ? 79 SER C CB 1 ATOM 3838 O OG . SER C 1 98 ? 4.799 45.883 -38.539 1.00 33.77 ? 79 SER C OG 1 ATOM 3839 N N . SER C 1 99 ? 5.394 47.036 -41.709 1.00 20.36 ? 80 SER C N 1 ATOM 3840 C CA . SER C 1 99 ? 5.807 48.355 -42.216 1.00 24.16 ? 80 SER C CA 1 ATOM 3841 C C . SER C 1 99 ? 5.944 48.412 -43.726 1.00 22.21 ? 80 SER C C 1 ATOM 3842 O O . SER C 1 99 ? 6.587 49.313 -44.231 1.00 24.56 ? 80 SER C O 1 ATOM 3843 C CB . SER C 1 99 ? 7.141 48.818 -41.597 1.00 23.63 ? 80 SER C CB 1 ATOM 3844 O OG . SER C 1 99 ? 7.166 48.657 -40.185 1.00 28.34 ? 80 SER C OG 1 ATOM 3845 N N . LEU C 1 100 ? 5.365 47.451 -44.440 1.00 21.88 ? 81 LEU C N 1 ATOM 3846 C CA . LEU C 1 100 ? 5.497 47.368 -45.895 1.00 17.24 ? 81 LEU C CA 1 ATOM 3847 C C . LEU C 1 100 ? 4.184 46.971 -46.494 1.00 21.67 ? 81 LEU C C 1 ATOM 3848 O O . LEU C 1 100 ? 3.412 46.231 -45.871 1.00 19.60 ? 81 LEU C O 1 ATOM 3849 C CB . LEU C 1 100 ? 6.432 46.237 -46.279 1.00 21.12 ? 81 LEU C CB 1 ATOM 3850 C CG . LEU C 1 100 ? 7.888 46.307 -45.896 1.00 24.62 ? 81 LEU C CG 1 ATOM 3851 C CD1 . LEU C 1 100 ? 8.575 45.074 -46.396 1.00 21.19 ? 81 LEU C CD1 1 ATOM 3852 C CD2 . LEU C 1 100 ? 8.448 47.535 -46.544 1.00 28.57 ? 81 LEU C CD2 1 ATOM 3853 N N . TRP C 1 101 ? 3.944 47.396 -47.731 1.00 22.57 ? 82 TRP C N 1 ATOM 3854 C CA . TRP C 1 101 ? 2.852 46.802 -48.489 1.00 19.20 ? 82 TRP C CA 1 ATOM 3855 C C . TRP C 1 101 ? 3.250 45.385 -48.828 1.00 19.14 ? 82 TRP C C 1 ATOM 3856 O O . TRP C 1 101 ? 4.406 45.126 -49.142 1.00 22.07 ? 82 TRP C O 1 ATOM 3857 C CB . TRP C 1 101 ? 2.580 47.544 -49.779 1.00 21.49 ? 82 TRP C CB 1 ATOM 3858 C CG . TRP C 1 101 ? 1.520 46.884 -50.592 1.00 18.41 ? 82 TRP C CG 1 ATOM 3859 C CD1 . TRP C 1 101 ? 0.169 47.087 -50.510 1.00 18.66 ? 82 TRP C CD1 1 ATOM 3860 C CD2 . TRP C 1 101 ? 1.718 45.909 -51.617 1.00 18.40 ? 82 TRP C CD2 1 ATOM 3861 N NE1 . TRP C 1 101 ? -0.480 46.307 -51.436 1.00 16.46 ? 82 TRP C NE1 1 ATOM 3862 C CE2 . TRP C 1 101 ? 0.446 45.572 -52.123 1.00 16.12 ? 82 TRP C CE2 1 ATOM 3863 C CE3 . TRP C 1 101 ? 2.851 45.282 -52.154 1.00 21.70 ? 82 TRP C CE3 1 ATOM 3864 C CZ2 . TRP C 1 101 ? 0.274 44.633 -53.135 1.00 19.29 ? 82 TRP C CZ2 1 ATOM 3865 C CZ3 . TRP C 1 101 ? 2.685 44.342 -53.163 1.00 16.30 ? 82 TRP C CZ3 1 ATOM 3866 C CH2 . TRP C 1 101 ? 1.405 44.028 -53.645 1.00 18.07 ? 82 TRP C CH2 1 ATOM 3867 N N . VAL C 1 102 ? 2.279 44.480 -48.778 1.00 19.97 ? 83 VAL C N 1 ATOM 3868 C CA . VAL C 1 102 ? 2.489 43.057 -49.036 1.00 18.10 ? 83 VAL C CA 1 ATOM 3869 C C . VAL C 1 102 ? 1.315 42.582 -49.883 1.00 16.34 ? 83 VAL C C 1 ATOM 3870 O O . VAL C 1 102 ? 0.178 43.023 -49.674 1.00 20.94 ? 83 VAL C O 1 ATOM 3871 C CB . VAL C 1 102 ? 2.562 42.277 -47.692 1.00 13.65 ? 83 VAL C CB 1 ATOM 3872 C CG1 . VAL C 1 102 ? 2.110 40.844 -47.857 1.00 20.72 ? 83 VAL C CG1 1 ATOM 3873 C CG2 . VAL C 1 102 ? 3.957 42.347 -47.121 1.00 12.31 ? 83 VAL C CG2 1 ATOM 3874 N N . PRO C 1 103 ? 1.571 41.692 -50.849 1.00 13.89 ? 84 PRO C N 1 ATOM 3875 C CA . PRO C 1 103 ? 0.464 41.184 -51.685 1.00 15.56 ? 84 PRO C CA 1 ATOM 3876 C C . PRO C 1 103 ? -0.527 40.321 -50.905 1.00 16.33 ? 84 PRO C C 1 ATOM 3877 O O . PRO C 1 103 ? -0.107 39.561 -50.035 1.00 18.70 ? 84 PRO C O 1 ATOM 3878 C CB . PRO C 1 103 ? 1.173 40.374 -52.774 1.00 11.44 ? 84 PRO C CB 1 ATOM 3879 C CG . PRO C 1 103 ? 2.501 40.048 -52.195 1.00 15.68 ? 84 PRO C CG 1 ATOM 3880 C CD . PRO C 1 103 ? 2.881 41.173 -51.259 1.00 15.62 ? 84 PRO C CD 1 ATOM 3881 N N . ASP C 1 104 ? -1.820 40.450 -51.210 1.00 19.89 ? 85 ASP C N 1 ATOM 3882 C CA . ASP C 1 104 ? -2.880 39.735 -50.479 1.00 19.93 ? 85 ASP C CA 1 ATOM 3883 C C . ASP C 1 104 ? -3.140 38.353 -51.059 1.00 20.12 ? 85 ASP C C 1 ATOM 3884 O O . ASP C 1 104 ? -4.261 38.045 -51.466 1.00 19.95 ? 85 ASP C O 1 ATOM 3885 C CB . ASP C 1 104 ? -4.199 40.539 -50.433 1.00 21.52 ? 85 ASP C CB 1 ATOM 3886 C CG . ASP C 1 104 ? -4.773 40.841 -51.837 1.00 27.71 ? 85 ASP C CG 1 ATOM 3887 O OD1 . ASP C 1 104 ? -3.976 40.983 -52.795 1.00 29.69 ? 85 ASP C OD1 1 ATOM 3888 O OD2 . ASP C 1 104 ? -6.022 40.927 -51.983 1.00 22.73 ? 85 ASP C OD2 1 ATOM 3889 N N . LEU C 1 105 ? -2.110 37.509 -51.070 1.00 17.18 ? 86 LEU C N 1 ATOM 3890 C CA . LEU C 1 105 ? -2.260 36.156 -51.604 1.00 16.50 ? 86 LEU C CA 1 ATOM 3891 C C . LEU C 1 105 ? -3.043 35.241 -50.640 1.00 18.88 ? 86 LEU C C 1 ATOM 3892 O O . LEU C 1 105 ? -2.964 35.387 -49.405 1.00 18.74 ? 86 LEU C O 1 ATOM 3893 C CB . LEU C 1 105 ? -0.890 35.564 -51.932 1.00 17.08 ? 86 LEU C CB 1 ATOM 3894 C CG . LEU C 1 105 ? -0.036 36.410 -52.873 1.00 17.56 ? 86 LEU C CG 1 ATOM 3895 C CD1 . LEU C 1 105 ? 1.384 35.857 -52.962 1.00 17.99 ? 86 LEU C CD1 1 ATOM 3896 C CD2 . LEU C 1 105 ? -0.666 36.506 -54.266 1.00 17.44 ? 86 LEU C CD2 1 ATOM 3897 N N . ALA C 1 106 ? -3.807 34.317 -51.216 1.00 14.71 ? 87 ALA C N 1 ATOM 3898 C CA . ALA C 1 106 ? -4.557 33.326 -50.459 1.00 14.69 ? 87 ALA C CA 1 ATOM 3899 C C . ALA C 1 106 ? -4.573 32.007 -51.220 1.00 23.14 ? 87 ALA C C 1 ATOM 3900 O O . ALA C 1 106 ? -4.513 31.990 -52.459 1.00 23.30 ? 87 ALA C O 1 ATOM 3901 C CB . ALA C 1 106 ? -5.965 33.800 -50.217 1.00 12.07 ? 87 ALA C CB 1 ATOM 3902 N N . ALA C 1 107 ? -4.644 30.901 -50.480 1.00 24.62 ? 88 ALA C N 1 ATOM 3903 C CA . ALA C 1 107 ? -4.787 29.576 -51.087 1.00 22.30 ? 88 ALA C CA 1 ATOM 3904 C C . ALA C 1 107 ? -6.271 29.249 -51.195 1.00 20.23 ? 88 ALA C C 1 ATOM 3905 O O . ALA C 1 107 ? -6.958 29.092 -50.185 1.00 22.93 ? 88 ALA C O 1 ATOM 3906 C CB . ALA C 1 107 ? -4.052 28.517 -50.264 1.00 21.24 ? 88 ALA C CB 1 ATOM 3907 N N . TYR C 1 108 ? -6.765 29.149 -52.424 1.00 21.49 ? 89 TYR C N 1 ATOM 3908 C CA . TYR C 1 108 ? -8.198 28.976 -52.663 1.00 19.42 ? 89 TYR C CA 1 ATOM 3909 C C . TYR C 1 108 ? -8.771 27.695 -52.071 1.00 23.93 ? 89 TYR C C 1 ATOM 3910 O O . TYR C 1 108 ? -9.950 27.656 -51.709 1.00 18.51 ? 89 TYR C O 1 ATOM 3911 C CB . TYR C 1 108 ? -8.498 29.051 -54.161 1.00 20.14 ? 89 TYR C CB 1 ATOM 3912 C CG . TYR C 1 108 ? -8.584 30.472 -54.699 1.00 24.82 ? 89 TYR C CG 1 ATOM 3913 C CD1 . TYR C 1 108 ? -7.443 31.262 -54.827 1.00 23.20 ? 89 TYR C CD1 1 ATOM 3914 C CD2 . TYR C 1 108 ? -9.799 31.014 -55.087 1.00 19.92 ? 89 TYR C CD2 1 ATOM 3915 C CE1 . TYR C 1 108 ? -7.514 32.539 -55.300 1.00 22.94 ? 89 TYR C CE1 1 ATOM 3916 C CE2 . TYR C 1 108 ? -9.884 32.293 -55.571 1.00 18.95 ? 89 TYR C CE2 1 ATOM 3917 C CZ . TYR C 1 108 ? -8.742 33.056 -55.672 1.00 26.12 ? 89 TYR C CZ 1 ATOM 3918 O OH . TYR C 1 108 ? -8.822 34.345 -56.159 1.00 32.28 ? 89 TYR C OH 1 ATOM 3919 N N . ASN C 1 109 ? -7.945 26.647 -51.988 1.00 25.83 ? 90 ASN C N 1 ATOM 3920 C CA . ASN C 1 109 ? -8.428 25.350 -51.519 1.00 23.61 ? 90 ASN C CA 1 ATOM 3921 C C . ASN C 1 109 ? -7.864 25.005 -50.148 1.00 24.14 ? 90 ASN C C 1 ATOM 3922 O O . ASN C 1 109 ? -7.789 23.836 -49.755 1.00 34.15 ? 90 ASN C O 1 ATOM 3923 C CB . ASN C 1 109 ? -8.176 24.231 -52.552 1.00 21.46 ? 90 ASN C CB 1 ATOM 3924 C CG . ASN C 1 109 ? -6.705 24.042 -52.871 1.00 19.02 ? 90 ASN C CG 1 ATOM 3925 O OD1 . ASN C 1 109 ? -5.996 24.993 -53.159 1.00 22.25 ? 90 ASN C OD1 1 ATOM 3926 N ND2 . ASN C 1 109 ? -6.240 22.804 -52.800 1.00 25.33 ? 90 ASN C ND2 1 ATOM 3927 N N . ALA C 1 110 ? -7.460 26.031 -49.414 1.00 18.25 ? 91 ALA C N 1 ATOM 3928 C CA . ALA C 1 110 ? -7.041 25.839 -48.028 1.00 19.16 ? 91 ALA C CA 1 ATOM 3929 C C . ALA C 1 110 ? -8.286 25.625 -47.163 1.00 18.98 ? 91 ALA C C 1 ATOM 3930 O O . ALA C 1 110 ? -9.341 26.195 -47.435 1.00 20.97 ? 91 ALA C O 1 ATOM 3931 C CB . ALA C 1 110 ? -6.240 27.037 -47.544 1.00 17.53 ? 91 ALA C CB 1 ATOM 3932 N N . ILE C 1 111 ? -8.186 24.783 -46.143 1.00 17.50 ? 92 ILE C N 1 ATOM 3933 C CA . ILE C 1 111 ? -9.325 24.591 -45.260 1.00 18.90 ? 92 ILE C CA 1 ATOM 3934 C C . ILE C 1 111 ? -8.979 24.937 -43.817 1.00 19.61 ? 92 ILE C C 1 ATOM 3935 O O . ILE C 1 111 ? -9.732 24.615 -42.896 1.00 17.36 ? 92 ILE C O 1 ATOM 3936 C CB . ILE C 1 111 ? -9.902 23.173 -45.351 1.00 21.05 ? 92 ILE C CB 1 ATOM 3937 C CG1 . ILE C 1 111 ? -8.827 22.128 -45.089 1.00 23.46 ? 92 ILE C CG1 1 ATOM 3938 C CG2 . ILE C 1 111 ? -10.528 22.942 -46.708 1.00 21.98 ? 92 ILE C CG2 1 ATOM 3939 C CD1 . ILE C 1 111 ? -9.364 20.715 -45.057 1.00 24.40 ? 92 ILE C CD1 1 ATOM 3940 N N . SER C 1 112 ? -7.839 25.603 -43.645 1.00 17.46 ? 93 SER C N 1 ATOM 3941 C CA . SER C 1 112 ? -7.434 26.171 -42.358 1.00 26.21 ? 93 SER C CA 1 ATOM 3942 C C . SER C 1 112 ? -6.680 27.445 -42.674 1.00 22.68 ? 93 SER C C 1 ATOM 3943 O O . SER C 1 112 ? -6.199 27.593 -43.799 1.00 21.06 ? 93 SER C O 1 ATOM 3944 C CB . SER C 1 112 ? -6.532 25.191 -41.603 1.00 28.40 ? 93 SER C CB 1 ATOM 3945 O OG . SER C 1 112 ? -5.261 25.066 -42.231 1.00 29.66 ? 93 SER C OG 1 ATOM 3946 N N . LYS C 1 113 ? -6.556 28.361 -41.716 1.00 26.34 ? 94 LYS C N 1 ATOM 3947 C CA . LYS C 1 113 ? -5.756 29.572 -41.981 1.00 26.93 ? 94 LYS C CA 1 ATOM 3948 C C . LYS C 1 113 ? -4.254 29.262 -41.905 1.00 26.08 ? 94 LYS C C 1 ATOM 3949 O O . LYS C 1 113 ? -3.850 28.320 -41.225 1.00 29.17 ? 94 LYS C O 1 ATOM 3950 C CB . LYS C 1 113 ? -6.149 30.747 -41.071 1.00 26.82 ? 94 LYS C CB 1 ATOM 3951 C CG . LYS C 1 113 ? -5.877 30.550 -39.586 1.00 38.20 ? 94 LYS C CG 1 ATOM 3952 C CD . LYS C 1 113 ? -6.561 31.663 -38.777 1.00 49.27 ? 94 LYS C CD 1 ATOM 3953 C CE . LYS C 1 113 ? -6.214 33.052 -39.329 1.00 54.78 ? 94 LYS C CE 1 ATOM 3954 N NZ . LYS C 1 113 ? -6.649 34.182 -38.440 1.00 58.07 ? 94 LYS C NZ 1 ATOM 3955 N N . PRO C 1 114 ? -3.427 30.026 -42.638 1.00 25.17 ? 95 PRO C N 1 ATOM 3956 C CA . PRO C 1 114 ? -1.988 29.753 -42.606 1.00 19.47 ? 95 PRO C CA 1 ATOM 3957 C C . PRO C 1 114 ? -1.439 29.899 -41.198 1.00 21.57 ? 95 PRO C C 1 ATOM 3958 O O . PRO C 1 114 ? -1.736 30.884 -40.537 1.00 25.48 ? 95 PRO C O 1 ATOM 3959 C CB . PRO C 1 114 ? -1.406 30.868 -43.471 1.00 16.41 ? 95 PRO C CB 1 ATOM 3960 C CG . PRO C 1 114 ? -2.541 31.404 -44.249 1.00 16.21 ? 95 PRO C CG 1 ATOM 3961 C CD . PRO C 1 114 ? -3.752 31.210 -43.454 1.00 21.68 ? 95 PRO C CD 1 ATOM 3962 N N . GLU C 1 115 ? -0.659 28.928 -40.744 1.00 24.74 ? 96 GLU C N 1 ATOM 3963 C CA . GLU C 1 115 ? 0.037 29.030 -39.468 1.00 22.92 ? 96 GLU C CA 1 ATOM 3964 C C . GLU C 1 115 ? 1.481 29.412 -39.775 1.00 23.60 ? 96 GLU C C 1 ATOM 3965 O O . GLU C 1 115 ? 2.234 28.595 -40.324 1.00 21.30 ? 96 GLU C O 1 ATOM 3966 C CB . GLU C 1 115 ? 0.001 27.687 -38.750 1.00 21.16 ? 96 GLU C CB 1 ATOM 3967 C CG . GLU C 1 115 ? 0.556 27.696 -37.329 1.00 39.37 ? 96 GLU C CG 1 ATOM 3968 C CD . GLU C 1 115 ? 0.424 26.321 -36.652 1.00 58.45 ? 96 GLU C CD 1 ATOM 3969 O OE1 . GLU C 1 115 ? -0.380 25.495 -37.164 1.00 61.40 ? 96 GLU C OE1 1 ATOM 3970 O OE2 . GLU C 1 115 ? 1.124 26.064 -35.628 1.00 58.23 ? 96 GLU C OE2 1 ATOM 3971 N N . VAL C 1 116 ? 1.870 30.648 -39.448 1.00 24.45 ? 97 VAL C N 1 ATOM 3972 C CA . VAL C 1 116 ? 3.219 31.132 -39.796 1.00 20.84 ? 97 VAL C CA 1 ATOM 3973 C C . VAL C 1 116 ? 4.263 30.753 -38.767 1.00 18.23 ? 97 VAL C C 1 ATOM 3974 O O . VAL C 1 116 ? 4.204 31.177 -37.618 1.00 19.27 ? 97 VAL C O 1 ATOM 3975 C CB . VAL C 1 116 ? 3.272 32.643 -40.055 1.00 18.68 ? 97 VAL C CB 1 ATOM 3976 C CG1 . VAL C 1 116 ? 4.637 33.022 -40.546 1.00 14.32 ? 97 VAL C CG1 1 ATOM 3977 C CG2 . VAL C 1 116 ? 2.253 33.032 -41.087 1.00 20.89 ? 97 VAL C CG2 1 ATOM 3978 N N . LEU C 1 117 ? 5.233 29.955 -39.198 1.00 19.50 ? 98 LEU C N 1 ATOM 3979 C CA . LEU C 1 117 ? 6.171 29.334 -38.273 1.00 19.95 ? 98 LEU C CA 1 ATOM 3980 C C . LEU C 1 117 ? 7.380 30.201 -37.936 1.00 21.12 ? 98 LEU C C 1 ATOM 3981 O O . LEU C 1 117 ? 8.015 30.018 -36.891 1.00 19.22 ? 98 LEU C O 1 ATOM 3982 C CB . LEU C 1 117 ? 6.618 27.983 -38.828 1.00 19.34 ? 98 LEU C CB 1 ATOM 3983 C CG . LEU C 1 117 ? 5.518 26.927 -39.023 1.00 19.32 ? 98 LEU C CG 1 ATOM 3984 C CD1 . LEU C 1 117 ? 6.131 25.630 -39.565 1.00 16.10 ? 98 LEU C CD1 1 ATOM 3985 C CD2 . LEU C 1 117 ? 4.686 26.664 -37.756 1.00 13.20 ? 98 LEU C CD2 1 ATOM 3986 N N . THR C 1 118 ? 7.680 31.149 -38.817 1.00 17.75 ? 99 THR C N 1 ATOM 3987 C CA . THR C 1 118 ? 8.926 31.903 -38.725 1.00 17.86 ? 99 THR C CA 1 ATOM 3988 C C . THR C 1 118 ? 8.679 33.368 -38.378 1.00 20.03 ? 99 THR C C 1 ATOM 3989 O O . THR C 1 118 ? 7.539 33.838 -38.477 1.00 18.15 ? 99 THR C O 1 ATOM 3990 C CB . THR C 1 118 ? 9.673 31.814 -40.052 1.00 19.37 ? 99 THR C CB 1 ATOM 3991 O OG1 . THR C 1 118 ? 8.759 32.126 -41.112 1.00 25.39 ? 99 THR C OG1 1 ATOM 3992 C CG2 . THR C 1 118 ? 10.199 30.414 -40.248 1.00 19.58 ? 99 THR C CG2 1 ATOM 3993 N N . PRO C 1 119 ? 9.744 34.093 -37.973 1.00 20.69 ? 100 PRO C N 1 ATOM 3994 C CA . PRO C 1 119 ? 9.680 35.553 -37.778 1.00 23.19 ? 100 PRO C CA 1 ATOM 3995 C C . PRO C 1 119 ? 9.116 36.242 -39.015 1.00 21.26 ? 100 PRO C C 1 ATOM 3996 O O . PRO C 1 119 ? 9.450 35.841 -40.150 1.00 18.00 ? 100 PRO C O 1 ATOM 3997 C CB . PRO C 1 119 ? 11.153 35.949 -37.597 1.00 17.16 ? 100 PRO C CB 1 ATOM 3998 C CG . PRO C 1 119 ? 11.797 34.737 -37.012 1.00 16.28 ? 100 PRO C CG 1 ATOM 3999 C CD . PRO C 1 119 ? 11.050 33.539 -37.566 1.00 19.44 ? 100 PRO C CD 1 ATOM 4000 N N . GLN C 1 120 ? 8.282 37.260 -38.805 1.00 20.70 ? 101 GLN C N 1 ATOM 4001 C CA . GLN C 1 120 ? 7.653 37.946 -39.936 1.00 23.75 ? 101 GLN C CA 1 ATOM 4002 C C . GLN C 1 120 ? 8.438 39.177 -40.472 1.00 25.34 ? 101 GLN C C 1 ATOM 4003 O O . GLN C 1 120 ? 7.989 40.338 -40.392 1.00 23.20 ? 101 GLN C O 1 ATOM 4004 C CB . GLN C 1 120 ? 6.178 38.239 -39.635 1.00 22.59 ? 101 GLN C CB 1 ATOM 4005 C CG . GLN C 1 120 ? 5.323 36.975 -39.592 1.00 23.49 ? 101 GLN C CG 1 ATOM 4006 C CD . GLN C 1 120 ? 3.909 37.205 -39.082 1.00 31.30 ? 101 GLN C CD 1 ATOM 4007 O OE1 . GLN C 1 120 ? 3.257 38.188 -39.437 1.00 51.25 ? 101 GLN C OE1 1 ATOM 4008 N NE2 . GLN C 1 120 ? 3.430 36.295 -38.239 1.00 30.47 ? 101 GLN C NE2 1 ATOM 4009 N N . LEU C 1 121 ? 9.612 38.888 -41.033 1.00 22.19 ? 102 LEU C N 1 ATOM 4010 C CA . LEU C 1 121 ? 10.486 39.902 -41.606 1.00 17.91 ? 102 LEU C CA 1 ATOM 4011 C C . LEU C 1 121 ? 10.646 39.701 -43.098 1.00 25.63 ? 102 LEU C C 1 ATOM 4012 O O . LEU C 1 121 ? 10.731 38.561 -43.576 1.00 28.70 ? 102 LEU C O 1 ATOM 4013 C CB . LEU C 1 121 ? 11.866 39.813 -40.975 1.00 19.48 ? 102 LEU C CB 1 ATOM 4014 C CG . LEU C 1 121 ? 11.880 40.042 -39.467 1.00 22.71 ? 102 LEU C CG 1 ATOM 4015 C CD1 . LEU C 1 121 ? 13.294 39.951 -38.899 1.00 19.84 ? 102 LEU C CD1 1 ATOM 4016 C CD2 . LEU C 1 121 ? 11.251 41.389 -39.147 1.00 19.45 ? 102 LEU C CD2 1 ATOM 4017 N N . ALA C 1 122 ? 10.696 40.809 -43.835 1.00 28.04 ? 103 ALA C N 1 ATOM 4018 C CA . ALA C 1 122 ? 10.987 40.779 -45.274 1.00 20.86 ? 103 ALA C CA 1 ATOM 4019 C C . ALA C 1 122 ? 12.394 41.307 -45.544 1.00 22.77 ? 103 ALA C C 1 ATOM 4020 O O . ALA C 1 122 ? 12.930 42.144 -44.802 1.00 22.56 ? 103 ALA C O 1 ATOM 4021 C CB . ALA C 1 122 ? 9.959 41.585 -46.054 1.00 13.72 ? 103 ALA C CB 1 ATOM 4022 N N . HIS C 1 123 ? 12.986 40.820 -46.624 1.00 24.61 ? 104 HIS C N 1 ATOM 4023 C CA . HIS C 1 123 ? 14.310 41.256 -47.047 1.00 20.52 ? 104 HIS C CA 1 ATOM 4024 C C . HIS C 1 123 ? 14.134 42.365 -48.082 1.00 20.81 ? 104 HIS C C 1 ATOM 4025 O O . HIS C 1 123 ? 13.369 42.195 -49.030 1.00 27.16 ? 104 HIS C O 1 ATOM 4026 C CB . HIS C 1 123 ? 15.036 40.065 -47.654 1.00 23.73 ? 104 HIS C CB 1 ATOM 4027 C CG . HIS C 1 123 ? 16.496 40.282 -47.841 1.00 28.32 ? 104 HIS C CG 1 ATOM 4028 N ND1 . HIS C 1 123 ? 17.060 40.498 -49.079 1.00 32.55 ? 104 HIS C ND1 1 ATOM 4029 C CD2 . HIS C 1 123 ? 17.515 40.312 -46.946 1.00 33.72 ? 104 HIS C CD2 1 ATOM 4030 C CE1 . HIS C 1 123 ? 18.368 40.659 -48.940 1.00 38.63 ? 104 HIS C CE1 1 ATOM 4031 N NE2 . HIS C 1 123 ? 18.667 40.551 -47.657 1.00 39.31 ? 104 HIS C NE2 1 ATOM 4032 N N . VAL C 1 124 ? 14.812 43.498 -47.904 1.00 19.04 ? 105 VAL C N 1 ATOM 4033 C CA . VAL C 1 124 ? 14.676 44.629 -48.824 1.00 17.31 ? 105 VAL C CA 1 ATOM 4034 C C . VAL C 1 124 ? 16.048 45.025 -49.314 1.00 21.02 ? 105 VAL C C 1 ATOM 4035 O O . VAL C 1 124 ? 16.968 45.232 -48.523 1.00 24.46 ? 105 VAL C O 1 ATOM 4036 C CB . VAL C 1 124 ? 14.031 45.878 -48.155 1.00 18.11 ? 105 VAL C CB 1 ATOM 4037 C CG1 . VAL C 1 124 ? 13.799 46.983 -49.174 1.00 17.46 ? 105 VAL C CG1 1 ATOM 4038 C CG2 . VAL C 1 124 ? 12.739 45.530 -47.496 1.00 20.51 ? 105 VAL C CG2 1 ATOM 4039 N N . VAL C 1 125 ? 16.168 45.166 -50.624 1.00 22.96 ? 106 VAL C N 1 ATOM 4040 C CA . VAL C 1 125 ? 17.421 45.550 -51.265 1.00 29.20 ? 106 VAL C CA 1 ATOM 4041 C C . VAL C 1 125 ? 17.294 47.027 -51.668 1.00 26.14 ? 106 VAL C C 1 ATOM 4042 O O . VAL C 1 125 ? 16.188 47.473 -51.936 1.00 27.34 ? 106 VAL C O 1 ATOM 4043 C CB . VAL C 1 125 ? 17.696 44.619 -52.500 1.00 32.36 ? 106 VAL C CB 1 ATOM 4044 C CG1 . VAL C 1 125 ? 18.902 45.072 -53.281 1.00 36.80 ? 106 VAL C CG1 1 ATOM 4045 C CG2 . VAL C 1 125 ? 17.889 43.182 -52.051 1.00 25.37 ? 106 VAL C CG2 1 ATOM 4046 N N . SER C 1 126 ? 18.403 47.776 -51.705 1.00 24.96 ? 107 SER C N 1 ATOM 4047 C CA . SER C 1 126 ? 18.386 49.214 -52.022 1.00 24.23 ? 107 SER C CA 1 ATOM 4048 C C . SER C 1 126 ? 17.685 49.629 -53.320 1.00 29.89 ? 107 SER C C 1 ATOM 4049 O O . SER C 1 126 ? 17.280 50.787 -53.446 1.00 30.32 ? 107 SER C O 1 ATOM 4050 C CB . SER C 1 126 ? 19.789 49.788 -52.035 1.00 26.70 ? 107 SER C CB 1 ATOM 4051 O OG . SER C 1 126 ? 20.589 49.069 -52.952 1.00 40.47 ? 107 SER C OG 1 ATOM 4052 N N . ASP C 1 127 ? 17.548 48.717 -54.283 1.00 28.40 ? 108 ASP C N 1 ATOM 4053 C CA . ASP C 1 127 ? 16.823 49.052 -55.506 1.00 29.76 ? 108 ASP C CA 1 ATOM 4054 C C . ASP C 1 127 ? 15.293 49.061 -55.340 1.00 31.78 ? 108 ASP C C 1 ATOM 4055 O O . ASP C 1 127 ? 14.569 49.583 -56.188 1.00 40.53 ? 108 ASP C O 1 ATOM 4056 C CB . ASP C 1 127 ? 17.248 48.163 -56.695 1.00 37.15 ? 108 ASP C CB 1 ATOM 4057 C CG . ASP C 1 127 ? 17.024 46.666 -56.445 1.00 47.68 ? 108 ASP C CG 1 ATOM 4058 O OD1 . ASP C 1 127 ? 16.342 46.307 -55.446 1.00 43.98 ? 108 ASP C OD1 1 ATOM 4059 O OD2 . ASP C 1 127 ? 17.530 45.846 -57.261 1.00 47.43 ? 108 ASP C OD2 1 ATOM 4060 N N . GLY C 1 128 ? 14.801 48.481 -54.255 1.00 30.17 ? 109 GLY C N 1 ATOM 4061 C CA . GLY C 1 128 ? 13.366 48.382 -54.049 1.00 28.43 ? 109 GLY C CA 1 ATOM 4062 C C . GLY C 1 128 ? 12.814 46.968 -54.161 1.00 27.85 ? 109 GLY C C 1 ATOM 4063 O O . GLY C 1 128 ? 11.603 46.769 -54.141 1.00 22.28 ? 109 GLY C O 1 ATOM 4064 N N . GLU C 1 129 ? 13.701 45.984 -54.277 1.00 30.95 ? 110 GLU C N 1 ATOM 4065 C CA . GLU C 1 129 ? 13.279 44.590 -54.396 1.00 31.14 ? 110 GLU C CA 1 ATOM 4066 C C . GLU C 1 129 ? 12.997 43.976 -53.032 1.00 31.22 ? 110 GLU C C 1 ATOM 4067 O O . GLU C 1 129 ? 13.837 44.010 -52.125 1.00 30.13 ? 110 GLU C O 1 ATOM 4068 C CB . GLU C 1 129 ? 14.336 43.757 -55.124 1.00 34.63 ? 110 GLU C CB 1 ATOM 4069 C CG . GLU C 1 129 ? 14.227 43.788 -56.638 1.00 44.62 ? 110 GLU C CG 1 ATOM 4070 C CD . GLU C 1 129 ? 13.046 42.972 -57.155 1.00 60.37 ? 110 GLU C CD 1 ATOM 4071 O OE1 . GLU C 1 129 ? 12.888 41.806 -56.703 1.00 65.49 ? 110 GLU C OE1 1 ATOM 4072 O OE2 . GLU C 1 129 ? 12.280 43.501 -58.006 1.00 60.85 ? 110 GLU C OE2 1 ATOM 4073 N N . VAL C 1 130 ? 11.816 43.393 -52.893 1.00 27.91 ? 111 VAL C N 1 ATOM 4074 C CA . VAL C 1 130 ? 11.413 42.818 -51.624 1.00 19.36 ? 111 VAL C CA 1 ATOM 4075 C C . VAL C 1 130 ? 11.241 41.324 -51.765 1.00 22.79 ? 111 VAL C C 1 ATOM 4076 O O . VAL C 1 130 ? 10.699 40.847 -52.766 1.00 26.76 ? 111 VAL C O 1 ATOM 4077 C CB . VAL C 1 130 ? 10.110 43.435 -51.165 1.00 20.52 ? 111 VAL C CB 1 ATOM 4078 C CG1 . VAL C 1 130 ? 9.722 42.897 -49.795 1.00 16.97 ? 111 VAL C CG1 1 ATOM 4079 C CG2 . VAL C 1 130 ? 10.240 44.967 -51.166 1.00 19.74 ? 111 VAL C CG2 1 ATOM 4080 N N . GLN C 1 131 ? 11.712 40.576 -50.774 1.00 21.41 ? 112 GLN C N 1 ATOM 4081 C CA . GLN C 1 131 ? 11.426 39.144 -50.722 1.00 23.68 ? 112 GLN C CA 1 ATOM 4082 C C . GLN C 1 131 ? 10.896 38.756 -49.347 1.00 24.25 ? 112 GLN C C 1 ATOM 4083 O O . GLN C 1 131 ? 11.519 39.050 -48.329 1.00 28.73 ? 112 GLN C O 1 ATOM 4084 C CB . GLN C 1 131 ? 12.660 38.318 -51.052 1.00 24.17 ? 112 GLN C CB 1 ATOM 4085 C CG . GLN C 1 131 ? 12.396 36.833 -51.046 1.00 30.95 ? 112 GLN C CG 1 ATOM 4086 C CD . GLN C 1 131 ? 13.616 36.023 -51.447 1.00 41.44 ? 112 GLN C CD 1 ATOM 4087 O OE1 . GLN C 1 131 ? 14.349 36.389 -52.375 1.00 40.33 ? 112 GLN C OE1 1 ATOM 4088 N NE2 . GLN C 1 131 ? 13.840 34.909 -50.747 1.00 45.97 ? 112 GLN C NE2 1 ATOM 4089 N N . TYR C 1 132 ? 9.740 38.109 -49.315 1.00 16.22 ? 113 TYR C N 1 ATOM 4090 C CA . TYR C 1 132 ? 9.189 37.637 -48.062 1.00 18.95 ? 113 TYR C CA 1 ATOM 4091 C C . TYR C 1 132 ? 8.955 36.112 -48.140 1.00 26.98 ? 113 TYR C C 1 ATOM 4092 O O . TYR C 1 132 ? 8.162 35.630 -48.965 1.00 30.44 ? 113 TYR C O 1 ATOM 4093 C CB . TYR C 1 132 ? 7.909 38.415 -47.738 1.00 19.47 ? 113 TYR C CB 1 ATOM 4094 C CG . TYR C 1 132 ? 7.179 37.939 -46.501 1.00 18.60 ? 113 TYR C CG 1 ATOM 4095 C CD1 . TYR C 1 132 ? 7.869 37.685 -45.318 1.00 18.32 ? 113 TYR C CD1 1 ATOM 4096 C CD2 . TYR C 1 132 ? 5.801 37.761 -46.516 1.00 13.99 ? 113 TYR C CD2 1 ATOM 4097 C CE1 . TYR C 1 132 ? 7.208 37.239 -44.179 1.00 19.82 ? 113 TYR C CE1 1 ATOM 4098 C CE2 . TYR C 1 132 ? 5.124 37.314 -45.395 1.00 19.56 ? 113 TYR C CE2 1 ATOM 4099 C CZ . TYR C 1 132 ? 5.832 37.046 -44.224 1.00 22.86 ? 113 TYR C CZ 1 ATOM 4100 O OH . TYR C 1 132 ? 5.158 36.615 -43.097 1.00 21.10 ? 113 TYR C OH 1 ATOM 4101 N N . THR C 1 133 ? 9.659 35.353 -47.301 1.00 19.36 ? 114 THR C N 1 ATOM 4102 C CA . THR C 1 133 ? 9.620 33.896 -47.403 1.00 23.38 ? 114 THR C CA 1 ATOM 4103 C C . THR C 1 133 ? 9.285 33.251 -46.058 1.00 22.70 ? 114 THR C C 1 ATOM 4104 O O . THR C 1 133 ? 10.166 32.752 -45.346 1.00 22.32 ? 114 THR C O 1 ATOM 4105 C CB . THR C 1 133 ? 10.962 33.320 -47.935 1.00 27.30 ? 114 THR C CB 1 ATOM 4106 O OG1 . THR C 1 133 ? 11.433 34.093 -49.053 1.00 27.08 ? 114 THR C OG1 1 ATOM 4107 C CG2 . THR C 1 133 ? 10.829 31.836 -48.328 1.00 20.42 ? 114 THR C CG2 1 ATOM 4108 N N . PRO C 1 134 ? 7.999 33.265 -45.692 1.00 22.13 ? 115 PRO C N 1 ATOM 4109 C CA . PRO C 1 134 ? 7.637 32.613 -44.422 1.00 21.94 ? 115 PRO C CA 1 ATOM 4110 C C . PRO C 1 134 ? 7.519 31.104 -44.566 1.00 23.31 ? 115 PRO C C 1 ATOM 4111 O O . PRO C 1 134 ? 7.152 30.584 -45.643 1.00 24.06 ? 115 PRO C O 1 ATOM 4112 C CB . PRO C 1 134 ? 6.258 33.208 -44.103 1.00 19.47 ? 115 PRO C CB 1 ATOM 4113 C CG . PRO C 1 134 ? 5.682 33.564 -45.468 1.00 18.67 ? 115 PRO C CG 1 ATOM 4114 C CD . PRO C 1 134 ? 6.866 33.981 -46.314 1.00 20.62 ? 115 PRO C CD 1 ATOM 4115 N N . SER C 1 135 ? 7.821 30.388 -43.489 1.00 23.98 ? 116 SER C N 1 ATOM 4116 C CA . SER C 1 135 ? 7.488 28.964 -43.453 1.00 25.47 ? 116 SER C CA 1 ATOM 4117 C C . SER C 1 135 ? 6.058 28.799 -42.918 1.00 22.27 ? 116 SER C C 1 ATOM 4118 O O . SER C 1 135 ? 5.712 29.329 -41.863 1.00 21.60 ? 116 SER C O 1 ATOM 4119 C CB . SER C 1 135 ? 8.496 28.167 -42.621 1.00 23.30 ? 116 SER C CB 1 ATOM 4120 O OG . SER C 1 135 ? 8.220 26.771 -42.692 1.00 22.36 ? 116 SER C OG 1 ATOM 4121 N N . ILE C 1 136 ? 5.237 28.051 -43.647 1.00 24.70 ? 117 ILE C N 1 ATOM 4122 C CA . ILE C 1 136 ? 3.818 27.929 -43.341 1.00 20.32 ? 117 ILE C CA 1 ATOM 4123 C C . ILE C 1 136 ? 3.372 26.473 -43.224 1.00 20.60 ? 117 ILE C C 1 ATOM 4124 O O . ILE C 1 136 ? 3.675 25.652 -44.086 1.00 24.03 ? 117 ILE C O 1 ATOM 4125 C CB . ILE C 1 136 ? 2.980 28.635 -44.435 1.00 20.96 ? 117 ILE C CB 1 ATOM 4126 C CG1 . ILE C 1 136 ? 3.252 30.139 -44.409 1.00 19.74 ? 117 ILE C CG1 1 ATOM 4127 C CG2 . ILE C 1 136 ? 1.492 28.347 -44.273 1.00 21.42 ? 117 ILE C CG2 1 ATOM 4128 C CD1 . ILE C 1 136 ? 2.619 30.901 -45.565 1.00 24.10 ? 117 ILE C CD1 1 ATOM 4129 N N . ARG C 1 137 ? 2.644 26.158 -42.157 1.00 23.63 ? 118 ARG C N 1 ATOM 4130 C CA . ARG C 1 137 ? 1.914 24.900 -42.081 1.00 18.96 ? 118 ARG C CA 1 ATOM 4131 C C . ARG C 1 137 ? 0.447 25.169 -42.411 1.00 21.03 ? 118 ARG C C 1 ATOM 4132 O O . ARG C 1 137 ? -0.164 26.054 -41.819 1.00 25.87 ? 118 ARG C O 1 ATOM 4133 C CB . ARG C 1 137 ? 2.040 24.290 -40.685 1.00 17.01 ? 118 ARG C CB 1 ATOM 4134 C CG . ARG C 1 137 ? 1.078 23.127 -40.451 1.00 28.41 ? 118 ARG C CG 1 ATOM 4135 C CD . ARG C 1 137 ? 1.516 22.222 -39.307 1.00 34.70 ? 118 ARG C CD 1 ATOM 4136 N NE . ARG C 1 137 ? 0.656 21.046 -39.166 1.00 36.18 ? 118 ARG C NE 1 ATOM 4137 C CZ . ARG C 1 137 ? 0.902 20.023 -38.349 1.00 38.01 ? 118 ARG C CZ 1 ATOM 4138 N NH1 . ARG C 1 137 ? 1.995 20.007 -37.594 1.00 39.08 ? 118 ARG C NH1 1 ATOM 4139 N NH2 . ARG C 1 137 ? 0.058 19.005 -38.297 1.00 35.99 ? 118 ARG C NH2 1 ATOM 4140 N N . GLN C 1 138 ? -0.118 24.426 -43.363 1.00 23.01 ? 119 GLN C N 1 ATOM 4141 C CA . GLN C 1 138 ? -1.525 24.618 -43.749 1.00 28.71 ? 119 GLN C CA 1 ATOM 4142 C C . GLN C 1 138 ? -2.207 23.317 -44.185 1.00 27.74 ? 119 GLN C C 1 ATOM 4143 O O . GLN C 1 138 ? -1.561 22.430 -44.737 1.00 29.94 ? 119 GLN C O 1 ATOM 4144 C CB . GLN C 1 138 ? -1.650 25.687 -44.850 1.00 29.39 ? 119 GLN C CB 1 ATOM 4145 C CG . GLN C 1 138 ? -3.050 26.288 -45.012 1.00 21.27 ? 119 GLN C CG 1 ATOM 4146 C CD . GLN C 1 138 ? -2.999 27.604 -45.764 1.00 23.24 ? 119 GLN C CD 1 ATOM 4147 O OE1 . GLN C 1 138 ? -2.030 27.888 -46.480 1.00 22.13 ? 119 GLN C OE1 1 ATOM 4148 N NE2 . GLN C 1 138 ? -4.024 28.432 -45.582 1.00 28.86 ? 119 GLN C NE2 1 ATOM 4149 N N . ARG C 1 139 ? -3.515 23.214 -43.938 1.00 29.38 ? 120 ARG C N 1 ATOM 4150 C CA . ARG C 1 139 ? -4.299 22.054 -44.364 1.00 26.39 ? 120 ARG C CA 1 ATOM 4151 C C . ARG C 1 139 ? -5.087 22.356 -45.666 1.00 29.78 ? 120 ARG C C 1 ATOM 4152 O O . ARG C 1 139 ? -5.713 23.417 -45.803 1.00 26.05 ? 120 ARG C O 1 ATOM 4153 C CB . ARG C 1 139 ? -5.220 21.605 -43.226 1.00 24.92 ? 120 ARG C CB 1 ATOM 4154 C CG . ARG C 1 139 ? -5.817 20.244 -43.427 1.00 29.81 ? 120 ARG C CG 1 ATOM 4155 C CD . ARG C 1 139 ? -6.268 19.560 -42.116 1.00 46.37 ? 120 ARG C CD 1 ATOM 4156 N NE . ARG C 1 139 ? -6.683 18.169 -42.386 1.00 53.21 ? 120 ARG C NE 1 ATOM 4157 C CZ . ARG C 1 139 ? -5.871 17.109 -42.328 1.00 49.64 ? 120 ARG C CZ 1 ATOM 4158 N NH1 . ARG C 1 139 ? -4.595 17.257 -41.975 1.00 49.76 ? 120 ARG C NH1 1 ATOM 4159 N NH2 . ARG C 1 139 ? -6.336 15.896 -42.619 1.00 52.08 ? 120 ARG C NH2 1 ATOM 4160 N N . PHE C 1 140 ? -5.040 21.436 -46.631 1.00 32.85 ? 121 PHE C N 1 ATOM 4161 C CA . PHE C 1 140 ? -5.716 21.644 -47.922 1.00 27.55 ? 121 PHE C CA 1 ATOM 4162 C C . PHE C 1 140 ? -6.695 20.547 -48.294 1.00 30.82 ? 121 PHE C C 1 ATOM 4163 O O . PHE C 1 140 ? -6.645 19.430 -47.778 1.00 34.12 ? 121 PHE C O 1 ATOM 4164 C CB . PHE C 1 140 ? -4.709 21.745 -49.066 1.00 27.72 ? 121 PHE C CB 1 ATOM 4165 C CG . PHE C 1 140 ? -3.753 22.876 -48.930 1.00 27.92 ? 121 PHE C CG 1 ATOM 4166 C CD1 . PHE C 1 140 ? -2.580 22.725 -48.196 1.00 25.71 ? 121 PHE C CD1 1 ATOM 4167 C CD2 . PHE C 1 140 ? -4.017 24.092 -49.536 1.00 24.34 ? 121 PHE C CD2 1 ATOM 4168 C CE1 . PHE C 1 140 ? -1.679 23.779 -48.057 1.00 27.52 ? 121 PHE C CE1 1 ATOM 4169 C CE2 . PHE C 1 140 ? -3.116 25.158 -49.407 1.00 29.14 ? 121 PHE C CE2 1 ATOM 4170 C CZ . PHE C 1 140 ? -1.942 25.000 -48.662 1.00 25.36 ? 121 PHE C CZ 1 ATOM 4171 N N . SER C 1 141 ? -7.567 20.872 -49.238 1.00 31.97 ? 122 SER C N 1 ATOM 4172 C CA . SER C 1 141 ? -8.499 19.906 -49.798 1.00 29.93 ? 122 SER C CA 1 ATOM 4173 C C . SER C 1 141 ? -8.078 19.634 -51.234 1.00 33.58 ? 122 SER C C 1 ATOM 4174 O O . SER C 1 141 ? -8.096 20.544 -52.078 1.00 30.21 ? 122 SER C O 1 ATOM 4175 C CB . SER C 1 141 ? -9.920 20.464 -49.761 1.00 30.73 ? 122 SER C CB 1 ATOM 4176 O OG . SER C 1 141 ? -10.748 19.816 -50.711 1.00 32.30 ? 122 SER C OG 1 ATOM 4177 N N . CYS C 1 142 ? -7.686 18.389 -51.509 1.00 40.77 ? 123 CYS C N 1 ATOM 4178 C CA . CYS C 1 142 ? -7.217 18.022 -52.846 1.00 42.22 ? 123 CYS C CA 1 ATOM 4179 C C . CYS C 1 142 ? -7.328 16.535 -53.120 1.00 36.50 ? 123 CYS C C 1 ATOM 4180 O O . CYS C 1 142 ? -7.784 15.782 -52.267 1.00 37.50 ? 123 CYS C O 1 ATOM 4181 C CB . CYS C 1 142 ? -5.777 18.491 -53.042 1.00 49.05 ? 123 CYS C CB 1 ATOM 4182 S SG . CYS C 1 142 ? -4.656 17.929 -51.738 1.00 67.46 ? 123 CYS C SG 1 ATOM 4183 N N . ASP C 1 143 ? -6.904 16.120 -54.314 1.00 40.25 ? 124 ASP C N 1 ATOM 4184 C CA . ASP C 1 143 ? -6.984 14.712 -54.712 1.00 41.21 ? 124 ASP C CA 1 ATOM 4185 C C . ASP C 1 143 ? -5.850 13.868 -54.108 1.00 41.95 ? 124 ASP C C 1 ATOM 4186 O O . ASP C 1 143 ? -4.670 14.043 -54.439 1.00 39.56 ? 124 ASP C O 1 ATOM 4187 C CB . ASP C 1 143 ? -6.994 14.580 -56.234 1.00 40.72 ? 124 ASP C CB 1 ATOM 4188 C CG . ASP C 1 143 ? -7.544 13.240 -56.705 1.00 48.29 ? 124 ASP C CG 1 ATOM 4189 O OD1 . ASP C 1 143 ? -8.040 12.459 -55.853 1.00 49.80 ? 124 ASP C OD1 1 ATOM 4190 O OD2 . ASP C 1 143 ? -7.500 12.982 -57.933 1.00 51.39 ? 124 ASP C OD2 1 ATOM 4191 N N . VAL C 1 144 ? -6.230 12.948 -53.225 1.00 37.25 ? 125 VAL C N 1 ATOM 4192 C CA . VAL C 1 144 ? -5.282 12.167 -52.448 1.00 32.34 ? 125 VAL C CA 1 ATOM 4193 C C . VAL C 1 144 ? -5.208 10.717 -52.944 1.00 35.96 ? 125 VAL C C 1 ATOM 4194 O O . VAL C 1 144 ? -4.282 9.973 -52.601 1.00 40.14 ? 125 VAL C O 1 ATOM 4195 C CB . VAL C 1 144 ? -5.672 12.223 -50.961 1.00 32.91 ? 125 VAL C CB 1 ATOM 4196 C CG1 . VAL C 1 144 ? -4.682 11.475 -50.102 1.00 32.65 ? 125 VAL C CG1 1 ATOM 4197 C CG2 . VAL C 1 144 ? -5.746 13.657 -50.518 1.00 34.05 ? 125 VAL C CG2 1 ATOM 4198 N N . SER C 1 145 ? -6.176 10.331 -53.774 1.00 39.01 ? 126 SER C N 1 ATOM 4199 C CA . SER C 1 145 ? -6.265 8.961 -54.300 1.00 47.77 ? 126 SER C CA 1 ATOM 4200 C C . SER C 1 145 ? -4.962 8.479 -54.953 1.00 36.89 ? 126 SER C C 1 ATOM 4201 O O . SER C 1 145 ? -4.363 9.184 -55.771 1.00 40.47 ? 126 SER C O 1 ATOM 4202 C CB . SER C 1 145 ? -7.410 8.856 -55.309 1.00 47.40 ? 126 SER C CB 1 ATOM 4203 O OG . SER C 1 145 ? -7.175 9.727 -56.402 1.00 46.77 ? 126 SER C OG 1 ATOM 4204 N N . GLY C 1 146 ? -4.526 7.283 -54.573 1.00 32.28 ? 127 GLY C N 1 ATOM 4205 C CA . GLY C 1 146 ? -3.328 6.698 -55.148 1.00 40.19 ? 127 GLY C CA 1 ATOM 4206 C C . GLY C 1 146 ? -2.067 7.084 -54.405 1.00 39.28 ? 127 GLY C C 1 ATOM 4207 O O . GLY C 1 146 ? -0.951 6.961 -54.924 1.00 37.74 ? 127 GLY C O 1 ATOM 4208 N N . VAL C 1 147 ? -2.247 7.553 -53.178 1.00 35.44 ? 128 VAL C N 1 ATOM 4209 C CA . VAL C 1 147 ? -1.116 7.975 -52.370 1.00 34.71 ? 128 VAL C CA 1 ATOM 4210 C C . VAL C 1 147 ? -0.267 6.762 -51.978 1.00 43.18 ? 128 VAL C C 1 ATOM 4211 O O . VAL C 1 147 ? 0.945 6.876 -51.770 1.00 38.97 ? 128 VAL C O 1 ATOM 4212 C CB . VAL C 1 147 ? -1.578 8.791 -51.131 1.00 29.65 ? 128 VAL C CB 1 ATOM 4213 C CG1 . VAL C 1 147 ? -2.520 7.977 -50.259 1.00 30.18 ? 128 VAL C CG1 1 ATOM 4214 C CG2 . VAL C 1 147 ? -0.393 9.279 -50.336 1.00 27.32 ? 128 VAL C CG2 1 ATOM 4215 N N . ASP C 1 148 ? -0.910 5.594 -51.909 1.00 52.65 ? 129 ASP C N 1 ATOM 4216 C CA . ASP C 1 148 ? -0.238 4.351 -51.511 1.00 50.76 ? 129 ASP C CA 1 ATOM 4217 C C . ASP C 1 148 ? 0.071 3.457 -52.732 1.00 50.67 ? 129 ASP C C 1 ATOM 4218 O O . ASP C 1 148 ? 0.025 2.234 -52.663 1.00 57.11 ? 129 ASP C O 1 ATOM 4219 C CB . ASP C 1 148 ? -1.088 3.611 -50.469 1.00 59.23 ? 129 ASP C CB 1 ATOM 4220 C CG . ASP C 1 148 ? -0.242 2.888 -49.423 1.00 76.73 ? 129 ASP C CG 1 ATOM 4221 O OD1 . ASP C 1 148 ? 0.777 2.266 -49.801 1.00 80.15 ? 129 ASP C OD1 1 ATOM 4222 O OD2 . ASP C 1 148 ? -0.600 2.939 -48.221 1.00 84.99 ? 129 ASP C OD2 1 ATOM 4223 N N . THR C 1 149 ? 0.420 4.108 -53.836 1.00 54.10 ? 130 THR C N 1 ATOM 4224 C CA . THR C 1 149 ? 0.602 3.495 -55.147 1.00 41.48 ? 130 THR C CA 1 ATOM 4225 C C . THR C 1 149 ? 1.964 3.923 -55.693 1.00 47.41 ? 130 THR C C 1 ATOM 4226 O O . THR C 1 149 ? 2.508 4.941 -55.273 1.00 53.62 ? 130 THR C O 1 ATOM 4227 C CB . THR C 1 149 ? -0.534 3.970 -56.082 1.00 43.91 ? 130 THR C CB 1 ATOM 4228 O OG1 . THR C 1 149 ? -1.761 3.357 -55.668 1.00 36.35 ? 130 THR C OG1 1 ATOM 4229 C CG2 . THR C 1 149 ? -0.271 3.651 -57.556 1.00 53.97 ? 130 THR C CG2 1 ATOM 4230 N N . GLU C 1 150 ? 2.531 3.155 -56.613 1.00 46.57 ? 131 GLU C N 1 ATOM 4231 C CA . GLU C 1 150 ? 3.834 3.493 -57.153 1.00 45.41 ? 131 GLU C CA 1 ATOM 4232 C C . GLU C 1 150 ? 3.823 4.807 -57.943 1.00 44.74 ? 131 GLU C C 1 ATOM 4233 O O . GLU C 1 150 ? 4.837 5.496 -58.006 1.00 43.64 ? 131 GLU C O 1 ATOM 4234 C CB . GLU C 1 150 ? 4.343 2.350 -58.020 1.00 54.10 ? 131 GLU C CB 1 ATOM 4235 C CG . GLU C 1 150 ? 5.821 2.413 -58.329 1.00 62.96 ? 131 GLU C CG 1 ATOM 4236 C CD . GLU C 1 150 ? 6.177 1.551 -59.521 1.00 72.17 ? 131 GLU C CD 1 ATOM 4237 O OE1 . GLU C 1 150 ? 5.367 1.519 -60.477 1.00 64.06 ? 131 GLU C OE1 1 ATOM 4238 O OE2 . GLU C 1 150 ? 7.248 0.900 -59.497 1.00 87.99 ? 131 GLU C OE2 1 ATOM 4239 N N . SER C 1 151 ? 2.681 5.157 -58.533 1.00 45.08 ? 132 SER C N 1 ATOM 4240 C CA . SER C 1 151 ? 2.560 6.401 -59.316 1.00 47.50 ? 132 SER C CA 1 ATOM 4241 C C . SER C 1 151 ? 2.138 7.652 -58.506 1.00 46.10 ? 132 SER C C 1 ATOM 4242 O O . SER C 1 151 ? 2.230 8.781 -58.995 1.00 39.79 ? 132 SER C O 1 ATOM 4243 C CB . SER C 1 151 ? 1.601 6.190 -60.488 1.00 49.49 ? 132 SER C CB 1 ATOM 4244 O OG . SER C 1 151 ? 0.376 5.647 -60.036 1.00 61.30 ? 132 SER C OG 1 ATOM 4245 N N . GLY C 1 152 ? 1.651 7.439 -57.285 1.00 49.14 ? 133 GLY C N 1 ATOM 4246 C CA . GLY C 1 152 ? 1.407 8.522 -56.348 1.00 40.37 ? 133 GLY C CA 1 ATOM 4247 C C . GLY C 1 152 ? 0.115 9.302 -56.535 1.00 38.77 ? 133 GLY C C 1 ATOM 4248 O O . GLY C 1 152 ? -0.619 9.095 -57.502 1.00 45.94 ? 133 GLY C O 1 ATOM 4249 N N . ALA C 1 153 ? -0.168 10.200 -55.591 1.00 38.76 ? 134 ALA C N 1 ATOM 4250 C CA . ALA C 1 153 ? -1.268 11.160 -55.731 1.00 39.27 ? 134 ALA C CA 1 ATOM 4251 C C . ALA C 1 153 ? -0.760 12.473 -56.322 1.00 38.87 ? 134 ALA C C 1 ATOM 4252 O O . ALA C 1 153 ? 0.423 12.819 -56.189 1.00 40.08 ? 134 ALA C O 1 ATOM 4253 C CB . ALA C 1 153 ? -1.913 11.424 -54.386 1.00 34.35 ? 134 ALA C CB 1 ATOM 4254 N N . THR C 1 154 ? -1.648 13.214 -56.972 1.00 36.48 ? 135 THR C N 1 ATOM 4255 C CA . THR C 1 154 ? -1.279 14.561 -57.406 1.00 41.44 ? 135 THR C CA 1 ATOM 4256 C C . THR C 1 154 ? -2.223 15.593 -56.820 1.00 36.34 ? 135 THR C C 1 ATOM 4257 O O . THR C 1 154 ? -3.381 15.693 -57.226 1.00 37.83 ? 135 THR C O 1 ATOM 4258 C CB . THR C 1 154 ? -1.217 14.716 -58.944 1.00 43.90 ? 135 THR C CB 1 ATOM 4259 O OG1 . THR C 1 154 ? -0.448 13.644 -59.510 1.00 45.05 ? 135 THR C OG1 1 ATOM 4260 C CG2 . THR C 1 154 ? -0.574 16.050 -59.311 1.00 32.54 ? 135 THR C CG2 1 ATOM 4261 N N . CYS C 1 155 ? -1.706 16.348 -55.858 1.00 38.30 ? 136 CYS C N 1 ATOM 4262 C CA . CYS C 1 155 ? -2.463 17.387 -55.179 1.00 44.40 ? 136 CYS C CA 1 ATOM 4263 C C . CYS C 1 155 ? -2.131 18.750 -55.788 1.00 39.35 ? 136 CYS C C 1 ATOM 4264 O O . CYS C 1 155 ? -0.953 19.064 -55.932 1.00 41.37 ? 136 CYS C O 1 ATOM 4265 C CB . CYS C 1 155 ? -2.097 17.377 -53.691 1.00 47.69 ? 136 CYS C CB 1 ATOM 4266 S SG . CYS C 1 155 ? -2.978 18.624 -52.687 1.00 86.00 ? 136 CYS C SG 1 ATOM 4267 N N . ARG C 1 156 ? -3.148 19.542 -56.157 1.00 41.51 ? 137 ARG C N 1 ATOM 4268 C CA . ARG C 1 156 ? -2.929 20.896 -56.703 1.00 34.53 ? 137 ARG C CA 1 ATOM 4269 C C . ARG C 1 156 ? -3.262 21.970 -55.679 1.00 33.18 ? 137 ARG C C 1 ATOM 4270 O O . ARG C 1 156 ? -4.289 21.890 -55.012 1.00 42.54 ? 137 ARG C O 1 ATOM 4271 C CB . ARG C 1 156 ? -3.762 21.150 -57.971 1.00 35.54 ? 137 ARG C CB 1 ATOM 4272 C CG . ARG C 1 156 ? -3.817 19.983 -58.976 1.00 52.48 ? 137 ARG C CG 1 ATOM 4273 C CD . ARG C 1 156 ? -4.609 20.347 -60.267 1.00 56.53 ? 137 ARG C CD 1 ATOM 4274 N NE . ARG C 1 156 ? -5.772 21.211 -60.021 1.00 67.85 ? 137 ARG C NE 1 ATOM 4275 C CZ . ARG C 1 156 ? -7.013 20.777 -59.769 1.00 69.98 ? 137 ARG C CZ 1 ATOM 4276 N NH1 . ARG C 1 156 ? -7.273 19.475 -59.730 1.00 51.09 ? 137 ARG C NH1 1 ATOM 4277 N NH2 . ARG C 1 156 ? -8.003 21.646 -59.552 1.00 60.73 ? 137 ARG C NH2 1 ATOM 4278 N N . ILE C 1 157 ? -2.402 22.981 -55.563 1.00 34.19 ? 138 ILE C N 1 ATOM 4279 C CA . ILE C 1 157 ? -2.663 24.130 -54.687 1.00 27.81 ? 138 ILE C CA 1 ATOM 4280 C C . ILE C 1 157 ? -2.764 25.411 -55.497 1.00 24.52 ? 138 ILE C C 1 ATOM 4281 O O . ILE C 1 157 ? -1.849 25.766 -56.238 1.00 25.21 ? 138 ILE C O 1 ATOM 4282 C CB . ILE C 1 157 ? -1.561 24.300 -53.638 1.00 23.53 ? 138 ILE C CB 1 ATOM 4283 C CG1 . ILE C 1 157 ? -1.484 23.062 -52.754 1.00 26.01 ? 138 ILE C CG1 1 ATOM 4284 C CG2 . ILE C 1 157 ? -1.806 25.533 -52.801 1.00 20.50 ? 138 ILE C CG2 1 ATOM 4285 C CD1 . ILE C 1 157 ? -0.583 23.234 -51.568 1.00 23.43 ? 138 ILE C CD1 1 ATOM 4286 N N . LYS C 1 158 ? -3.880 26.107 -55.348 1.00 25.54 ? 139 LYS C N 1 ATOM 4287 C CA . LYS C 1 158 ? -4.148 27.300 -56.141 1.00 28.24 ? 139 LYS C CA 1 ATOM 4288 C C . LYS C 1 158 ? -3.948 28.567 -55.288 1.00 27.46 ? 139 LYS C C 1 ATOM 4289 O O . LYS C 1 158 ? -4.629 28.763 -54.280 1.00 27.68 ? 139 LYS C O 1 ATOM 4290 C CB . LYS C 1 158 ? -5.569 27.223 -56.716 1.00 22.87 ? 139 LYS C CB 1 ATOM 4291 C CG . LYS C 1 158 ? -6.015 28.455 -57.483 1.00 28.85 ? 139 LYS C CG 1 ATOM 4292 C CD . LYS C 1 158 ? -7.534 28.435 -57.712 1.00 24.73 ? 139 LYS C CD 1 ATOM 4293 C CE . LYS C 1 158 ? -8.069 29.816 -58.086 1.00 24.51 ? 139 LYS C CE 1 ATOM 4294 N NZ . LYS C 1 158 ? -9.496 29.757 -58.501 1.00 25.94 ? 139 LYS C NZ 1 ATOM 4295 N N . ILE C 1 159 ? -3.006 29.417 -55.690 1.00 28.12 ? 140 ILE C N 1 ATOM 4296 C CA . ILE C 1 159 ? -2.662 30.619 -54.932 1.00 22.94 ? 140 ILE C CA 1 ATOM 4297 C C . ILE C 1 159 ? -2.756 31.875 -55.785 1.00 25.61 ? 140 ILE C C 1 ATOM 4298 O O . ILE C 1 159 ? -2.185 31.940 -56.873 1.00 28.69 ? 140 ILE C O 1 ATOM 4299 C CB . ILE C 1 159 ? -1.231 30.519 -54.397 1.00 25.52 ? 140 ILE C CB 1 ATOM 4300 C CG1 . ILE C 1 159 ? -1.118 29.336 -53.426 1.00 26.84 ? 140 ILE C CG1 1 ATOM 4301 C CG2 . ILE C 1 159 ? -0.814 31.826 -53.734 1.00 24.51 ? 140 ILE C CG2 1 ATOM 4302 C CD1 . ILE C 1 159 ? 0.231 29.217 -52.738 1.00 27.66 ? 140 ILE C CD1 1 ATOM 4303 N N . GLY C 1 160 ? -3.467 32.886 -55.297 1.00 28.98 ? 141 GLY C N 1 ATOM 4304 C CA . GLY C 1 160 ? -3.600 34.129 -56.050 1.00 31.90 ? 141 GLY C CA 1 ATOM 4305 C C . GLY C 1 160 ? -3.994 35.329 -55.215 1.00 23.08 ? 141 GLY C C 1 ATOM 4306 O O . GLY C 1 160 ? -4.260 35.199 -54.027 1.00 24.52 ? 141 GLY C O 1 ATOM 4307 N N . SER C 1 161 ? -4.021 36.507 -55.827 1.00 29.16 ? 142 SER C N 1 ATOM 4308 C CA . SER C 1 161 ? -4.524 37.694 -55.131 1.00 24.43 ? 142 SER C CA 1 ATOM 4309 C C . SER C 1 161 ? -6.024 37.608 -54.845 1.00 22.67 ? 142 SER C C 1 ATOM 4310 O O . SER C 1 161 ? -6.815 37.227 -55.708 1.00 28.02 ? 142 SER C O 1 ATOM 4311 C CB . SER C 1 161 ? -4.271 38.942 -55.944 1.00 20.94 ? 142 SER C CB 1 ATOM 4312 O OG . SER C 1 161 ? -4.889 40.023 -55.279 1.00 25.94 ? 142 SER C OG 1 ATOM 4313 N N . TRP C 1 162 ? -6.421 37.986 -53.638 1.00 22.05 ? 143 TRP C N 1 ATOM 4314 C CA . TRP C 1 162 ? -7.809 37.829 -53.233 1.00 20.44 ? 143 TRP C CA 1 ATOM 4315 C C . TRP C 1 162 ? -8.685 38.985 -53.712 1.00 23.60 ? 143 TRP C C 1 ATOM 4316 O O . TRP C 1 162 ? -9.846 38.778 -54.056 1.00 24.90 ? 143 TRP C O 1 ATOM 4317 C CB . TRP C 1 162 ? -7.919 37.670 -51.707 1.00 20.05 ? 143 TRP C CB 1 ATOM 4318 C CG . TRP C 1 162 ? -9.262 37.149 -51.270 1.00 19.78 ? 143 TRP C CG 1 ATOM 4319 C CD1 . TRP C 1 162 ? -10.268 37.854 -50.654 1.00 21.50 ? 143 TRP C CD1 1 ATOM 4320 C CD2 . TRP C 1 162 ? -9.756 35.822 -51.440 1.00 19.02 ? 143 TRP C CD2 1 ATOM 4321 N NE1 . TRP C 1 162 ? -11.351 37.038 -50.435 1.00 18.70 ? 143 TRP C NE1 1 ATOM 4322 C CE2 . TRP C 1 162 ? -11.059 35.777 -50.906 1.00 17.77 ? 143 TRP C CE2 1 ATOM 4323 C CE3 . TRP C 1 162 ? -9.226 34.655 -52.005 1.00 21.68 ? 143 TRP C CE3 1 ATOM 4324 C CZ2 . TRP C 1 162 ? -11.835 34.630 -50.912 1.00 20.86 ? 143 TRP C CZ2 1 ATOM 4325 C CZ3 . TRP C 1 162 ? -9.992 33.510 -52.008 1.00 18.99 ? 143 TRP C CZ3 1 ATOM 4326 C CH2 . TRP C 1 162 ? -11.283 33.504 -51.469 1.00 20.51 ? 143 TRP C CH2 1 ATOM 4327 N N . THR C 1 163 ? -8.136 40.199 -53.727 1.00 23.23 ? 144 THR C N 1 ATOM 4328 C CA . THR C 1 163 ? -8.931 41.378 -54.081 1.00 22.69 ? 144 THR C CA 1 ATOM 4329 C C . THR C 1 163 ? -8.415 42.186 -55.272 1.00 24.47 ? 144 THR C C 1 ATOM 4330 O O . THR C 1 163 ? -9.073 43.131 -55.701 1.00 36.75 ? 144 THR C O 1 ATOM 4331 C CB . THR C 1 163 ? -9.094 42.367 -52.902 1.00 22.35 ? 144 THR C CB 1 ATOM 4332 O OG1 . THR C 1 163 ? -7.844 43.020 -52.639 1.00 21.32 ? 144 THR C OG1 1 ATOM 4333 C CG2 . THR C 1 163 ? -9.617 41.661 -51.661 1.00 20.05 ? 144 THR C CG2 1 ATOM 4334 N N . HIS C 1 164 ? -7.246 41.859 -55.794 1.00 19.82 ? 145 HIS C N 1 ATOM 4335 C CA . HIS C 1 164 ? -6.699 42.654 -56.889 1.00 20.86 ? 145 HIS C CA 1 ATOM 4336 C C . HIS C 1 164 ? -6.754 41.898 -58.210 1.00 25.21 ? 145 HIS C C 1 ATOM 4337 O O . HIS C 1 164 ? -6.231 40.791 -58.315 1.00 27.93 ? 145 HIS C O 1 ATOM 4338 C CB . HIS C 1 164 ? -5.258 43.097 -56.586 1.00 21.45 ? 145 HIS C CB 1 ATOM 4339 C CG . HIS C 1 164 ? -5.145 44.077 -55.455 1.00 26.25 ? 145 HIS C CG 1 ATOM 4340 N ND1 . HIS C 1 164 ? -5.574 45.381 -55.555 1.00 29.74 ? 145 HIS C ND1 1 ATOM 4341 C CD2 . HIS C 1 164 ? -4.640 43.940 -54.199 1.00 23.52 ? 145 HIS C CD2 1 ATOM 4342 C CE1 . HIS C 1 164 ? -5.341 46.013 -54.412 1.00 24.45 ? 145 HIS C CE1 1 ATOM 4343 N NE2 . HIS C 1 164 ? -4.779 45.155 -53.577 1.00 24.82 ? 145 HIS C NE2 1 ATOM 4344 N N . HIS C 1 165 ? -7.377 42.491 -59.227 1.00 32.66 ? 146 HIS C N 1 ATOM 4345 C CA . HIS C 1 165 ? -7.444 41.847 -60.548 1.00 32.47 ? 146 HIS C CA 1 ATOM 4346 C C . HIS C 1 165 ? -6.140 41.957 -61.372 1.00 29.68 ? 146 HIS C C 1 ATOM 4347 O O . HIS C 1 165 ? -5.142 42.505 -60.915 1.00 28.24 ? 146 HIS C O 1 ATOM 4348 C CB . HIS C 1 165 ? -8.655 42.338 -61.343 1.00 35.48 ? 146 HIS C CB 1 ATOM 4349 C CG . HIS C 1 165 ? -8.629 43.808 -61.629 1.00 41.96 ? 146 HIS C CG 1 ATOM 4350 N ND1 . HIS C 1 165 ? -7.661 44.396 -62.399 1.00 43.41 ? 146 HIS C ND1 1 ATOM 4351 C CD2 . HIS C 1 165 ? -9.470 44.804 -61.234 1.00 39.30 ? 146 HIS C CD2 1 ATOM 4352 C CE1 . HIS C 1 165 ? -7.891 45.705 -62.470 1.00 45.43 ? 146 HIS C CE1 1 ATOM 4353 N NE2 . HIS C 1 165 ? -8.983 45.965 -61.779 1.00 41.66 ? 146 HIS C NE2 1 ATOM 4354 N N . SER C 1 166 ? -6.167 41.436 -62.593 1.00 31.63 ? 147 SER C N 1 ATOM 4355 C CA . SER C 1 166 ? -4.948 41.179 -63.364 1.00 35.96 ? 147 SER C CA 1 ATOM 4356 C C . SER C 1 166 ? -4.183 42.421 -63.806 1.00 36.38 ? 147 SER C C 1 ATOM 4357 O O . SER C 1 166 ? -3.016 42.312 -64.188 1.00 32.17 ? 147 SER C O 1 ATOM 4358 C CB . SER C 1 166 ? -5.279 40.361 -64.601 1.00 34.62 ? 147 SER C CB 1 ATOM 4359 O OG . SER C 1 166 ? -6.146 41.107 -65.432 1.00 38.52 ? 147 SER C OG 1 ATOM 4360 N N . ARG C 1 167 ? -4.842 43.580 -63.781 1.00 36.03 ? 148 ARG C N 1 ATOM 4361 C CA . ARG C 1 167 ? -4.187 44.837 -64.153 1.00 38.68 ? 148 ARG C CA 1 ATOM 4362 C C . ARG C 1 167 ? -3.524 45.533 -62.952 1.00 41.20 ? 148 ARG C C 1 ATOM 4363 O O . ARG C 1 167 ? -2.789 46.514 -63.117 1.00 39.66 ? 148 ARG C O 1 ATOM 4364 C CB . ARG C 1 167 ? -5.168 45.791 -64.842 1.00 43.33 ? 148 ARG C CB 1 ATOM 4365 C CG . ARG C 1 167 ? -5.683 45.328 -66.188 1.00 51.22 ? 148 ARG C CG 1 ATOM 4366 C CD . ARG C 1 167 ? -6.580 46.399 -66.836 1.00 76.04 ? 148 ARG C CD 1 ATOM 4367 N NE . ARG C 1 167 ? -7.030 47.421 -65.883 1.00 78.11 ? 148 ARG C NE 1 ATOM 4368 C CZ . ARG C 1 167 ? -8.274 47.897 -65.809 1.00 83.42 ? 148 ARG C CZ 1 ATOM 4369 N NH1 . ARG C 1 167 ? -9.219 47.445 -66.631 1.00 83.32 ? 148 ARG C NH1 1 ATOM 4370 N NH2 . ARG C 1 167 ? -8.577 48.825 -64.905 1.00 77.13 ? 148 ARG C NH2 1 ATOM 4371 N N . GLU C 1 168 ? -3.794 45.017 -61.752 1.00 34.44 ? 149 GLU C N 1 ATOM 4372 C CA . GLU C 1 168 ? -3.211 45.558 -60.529 1.00 33.62 ? 149 GLU C CA 1 ATOM 4373 C C . GLU C 1 168 ? -2.105 44.640 -59.984 1.00 33.97 ? 149 GLU C C 1 ATOM 4374 O O . GLU C 1 168 ? -1.024 45.112 -59.618 1.00 33.01 ? 149 GLU C O 1 ATOM 4375 C CB . GLU C 1 168 ? -4.300 45.840 -59.472 1.00 32.08 ? 149 GLU C CB 1 ATOM 4376 C CG . GLU C 1 168 ? -5.297 46.923 -59.870 1.00 35.77 ? 149 GLU C CG 1 ATOM 4377 C CD . GLU C 1 168 ? -6.488 47.036 -58.915 1.00 45.07 ? 149 GLU C CD 1 ATOM 4378 O OE1 . GLU C 1 168 ? -6.928 45.996 -58.354 1.00 38.66 ? 149 GLU C OE1 1 ATOM 4379 O OE2 . GLU C 1 168 ? -6.990 48.176 -58.739 1.00 55.94 ? 149 GLU C OE2 1 ATOM 4380 N N . ILE C 1 169 ? -2.386 43.336 -59.928 1.00 30.78 ? 150 ILE C N 1 ATOM 4381 C CA . ILE C 1 169 ? -1.401 42.331 -59.528 1.00 29.36 ? 150 ILE C CA 1 ATOM 4382 C C . ILE C 1 169 ? -1.390 41.190 -60.534 1.00 29.07 ? 150 ILE C C 1 ATOM 4383 O O . ILE C 1 169 ? -2.438 40.626 -60.865 1.00 26.14 ? 150 ILE C O 1 ATOM 4384 C CB . ILE C 1 169 ? -1.674 41.754 -58.109 1.00 23.43 ? 150 ILE C CB 1 ATOM 4385 C CG1 . ILE C 1 169 ? -1.365 42.806 -57.043 1.00 28.65 ? 150 ILE C CG1 1 ATOM 4386 C CG2 . ILE C 1 169 ? -0.837 40.494 -57.856 1.00 20.06 ? 150 ILE C CG2 1 ATOM 4387 C CD1 . ILE C 1 169 ? -1.558 42.331 -55.600 1.00 28.45 ? 150 ILE C CD1 1 ATOM 4388 N N . SER C 1 170 ? -0.203 40.862 -61.027 1.00 31.07 ? 151 SER C N 1 ATOM 4389 C CA . SER C 1 170 ? -0.009 39.636 -61.791 1.00 32.01 ? 151 SER C CA 1 ATOM 4390 C C . SER C 1 170 ? 0.885 38.678 -60.994 1.00 37.13 ? 151 SER C C 1 ATOM 4391 O O . SER C 1 170 ? 1.926 39.091 -60.453 1.00 36.98 ? 151 SER C O 1 ATOM 4392 C CB . SER C 1 170 ? 0.614 39.943 -63.153 1.00 35.04 ? 151 SER C CB 1 ATOM 4393 O OG . SER C 1 170 ? 1.964 40.354 -63.016 1.00 31.11 ? 151 SER C OG 1 ATOM 4394 N N . VAL C 1 171 ? 0.474 37.411 -60.908 1.00 34.22 ? 152 VAL C N 1 ATOM 4395 C CA . VAL C 1 171 ? 1.295 36.378 -60.272 1.00 32.61 ? 152 VAL C CA 1 ATOM 4396 C C . VAL C 1 171 ? 1.877 35.463 -61.321 1.00 36.23 ? 152 VAL C C 1 ATOM 4397 O O . VAL C 1 171 ? 1.198 35.101 -62.272 1.00 39.29 ? 152 VAL C O 1 ATOM 4398 C CB . VAL C 1 171 ? 0.501 35.516 -59.291 1.00 35.70 ? 152 VAL C CB 1 ATOM 4399 C CG1 . VAL C 1 171 ? 0.332 36.233 -57.965 1.00 39.02 ? 152 VAL C CG1 1 ATOM 4400 C CG2 . VAL C 1 171 ? -0.844 35.172 -59.885 1.00 42.70 ? 152 VAL C CG2 1 ATOM 4401 N N . ASP C 1 172 ? 3.141 35.095 -61.139 1.00 42.43 ? 153 ASP C N 1 ATOM 4402 C CA . ASP C 1 172 ? 3.871 34.273 -62.097 1.00 38.07 ? 153 ASP C CA 1 ATOM 4403 C C . ASP C 1 172 ? 4.763 33.297 -61.336 1.00 42.89 ? 153 ASP C C 1 ATOM 4404 O O . ASP C 1 172 ? 5.297 33.629 -60.278 1.00 46.29 ? 153 ASP C O 1 ATOM 4405 C CB . ASP C 1 172 ? 4.733 35.154 -63.009 1.00 43.85 ? 153 ASP C CB 1 ATOM 4406 C CG . ASP C 1 172 ? 4.040 36.475 -63.390 1.00 65.31 ? 153 ASP C CG 1 ATOM 4407 O OD1 . ASP C 1 172 ? 3.179 36.441 -64.310 1.00 57.50 ? 153 ASP C OD1 1 ATOM 4408 O OD2 . ASP C 1 172 ? 4.353 37.539 -62.769 1.00 62.49 ? 153 ASP C OD2 1 ATOM 4409 N N . PRO C 1 173 ? 4.924 32.079 -61.865 1.00 41.74 ? 154 PRO C N 1 ATOM 4410 C CA . PRO C 1 173 ? 5.849 31.093 -61.296 1.00 34.82 ? 154 PRO C CA 1 ATOM 4411 C C . PRO C 1 173 ? 7.286 31.539 -61.502 1.00 42.81 ? 154 PRO C C 1 ATOM 4412 O O . PRO C 1 173 ? 7.546 32.332 -62.408 1.00 45.54 ? 154 PRO C O 1 ATOM 4413 C CB . PRO C 1 173 ? 5.593 29.856 -62.144 1.00 38.84 ? 154 PRO C CB 1 ATOM 4414 C CG . PRO C 1 173 ? 4.242 30.087 -62.764 1.00 39.30 ? 154 PRO C CG 1 ATOM 4415 C CD . PRO C 1 173 ? 4.175 31.541 -63.009 1.00 36.64 ? 154 PRO C CD 1 ATOM 4416 N N . THR C 1 174 ? 8.207 31.034 -60.687 1.00 51.57 ? 155 THR C N 1 ATOM 4417 C CA . THR C 1 174 ? 9.619 31.425 -60.779 1.00 50.72 ? 155 THR C CA 1 ATOM 4418 C C . THR C 1 174 ? 10.387 30.671 -61.861 1.00 48.78 ? 155 THR C C 1 ATOM 4419 O O . THR C 1 174 ? 10.204 29.470 -62.045 1.00 48.90 ? 155 THR C O 1 ATOM 4420 C CB . THR C 1 174 ? 10.329 31.230 -59.439 1.00 47.74 ? 155 THR C CB 1 ATOM 4421 O OG1 . THR C 1 174 ? 9.814 32.179 -58.497 1.00 45.32 ? 155 THR C OG1 1 ATOM 4422 C CG2 . THR C 1 174 ? 11.826 31.433 -59.600 1.00 57.46 ? 155 THR C CG2 1 ATOM 4423 N N . SER C 1 181 ? 12.601 18.309 -53.881 1.00 38.05 ? 162 SER C N 1 ATOM 4424 C CA . SER C 1 181 ? 12.978 17.642 -52.634 1.00 51.77 ? 162 SER C CA 1 ATOM 4425 C C . SER C 1 181 ? 14.167 18.332 -51.980 1.00 55.15 ? 162 SER C C 1 ATOM 4426 O O . SER C 1 181 ? 14.706 17.835 -50.981 1.00 62.96 ? 162 SER C O 1 ATOM 4427 C CB . SER C 1 181 ? 13.324 16.152 -52.866 1.00 58.00 ? 162 SER C CB 1 ATOM 4428 O OG . SER C 1 181 ? 12.166 15.329 -53.013 1.00 64.20 ? 162 SER C OG 1 ATOM 4429 N N . GLU C 1 182 ? 14.580 19.465 -52.545 1.00 38.68 ? 163 GLU C N 1 ATOM 4430 C CA . GLU C 1 182 ? 15.813 20.112 -52.115 1.00 40.98 ? 163 GLU C CA 1 ATOM 4431 C C . GLU C 1 182 ? 15.853 20.392 -50.605 1.00 45.38 ? 163 GLU C C 1 ATOM 4432 O O . GLU C 1 182 ? 16.887 20.233 -49.959 1.00 45.31 ? 163 GLU C O 1 ATOM 4433 C CB . GLU C 1 182 ? 16.052 21.398 -52.908 1.00 48.59 ? 163 GLU C CB 1 ATOM 4434 C CG . GLU C 1 182 ? 17.443 21.975 -52.692 1.00 52.52 ? 163 GLU C CG 1 ATOM 4435 C CD . GLU C 1 182 ? 17.644 23.320 -53.377 1.00 72.18 ? 163 GLU C CD 1 ATOM 4436 O OE1 . GLU C 1 182 ? 16.716 23.797 -54.086 1.00 72.39 ? 163 GLU C OE1 1 ATOM 4437 O OE2 . GLU C 1 182 ? 18.742 23.900 -53.196 1.00 70.38 ? 163 GLU C OE2 1 ATOM 4438 N N . TYR C 1 183 ? 14.720 20.795 -50.042 1.00 41.26 ? 164 TYR C N 1 ATOM 4439 C CA . TYR C 1 183 ? 14.653 21.023 -48.614 1.00 34.42 ? 164 TYR C CA 1 ATOM 4440 C C . TYR C 1 183 ? 13.657 20.092 -47.955 1.00 36.80 ? 164 TYR C C 1 ATOM 4441 O O . TYR C 1 183 ? 13.306 20.282 -46.788 1.00 35.79 ? 164 TYR C O 1 ATOM 4442 C CB . TYR C 1 183 ? 14.258 22.462 -48.316 1.00 41.75 ? 164 TYR C CB 1 ATOM 4443 C CG . TYR C 1 183 ? 15.106 23.490 -49.020 1.00 50.71 ? 164 TYR C CG 1 ATOM 4444 C CD1 . TYR C 1 183 ? 16.469 23.588 -48.761 1.00 46.13 ? 164 TYR C CD1 1 ATOM 4445 C CD2 . TYR C 1 183 ? 14.538 24.374 -49.942 1.00 53.32 ? 164 TYR C CD2 1 ATOM 4446 C CE1 . TYR C 1 183 ? 17.250 24.534 -49.404 1.00 54.84 ? 164 TYR C CE1 1 ATOM 4447 C CE2 . TYR C 1 183 ? 15.304 25.320 -50.598 1.00 54.40 ? 164 TYR C CE2 1 ATOM 4448 C CZ . TYR C 1 183 ? 16.664 25.403 -50.325 1.00 61.57 ? 164 TYR C CZ 1 ATOM 4449 O OH . TYR C 1 183 ? 17.442 26.350 -50.970 1.00 58.58 ? 164 TYR C OH 1 ATOM 4450 N N . PHE C 1 184 ? 13.193 19.094 -48.700 1.00 36.99 ? 165 PHE C N 1 ATOM 4451 C CA . PHE C 1 184 ? 12.196 18.168 -48.169 1.00 38.24 ? 165 PHE C CA 1 ATOM 4452 C C . PHE C 1 184 ? 12.789 17.248 -47.103 1.00 39.51 ? 165 PHE C C 1 ATOM 4453 O O . PHE C 1 184 ? 13.908 16.757 -47.244 1.00 42.84 ? 165 PHE C O 1 ATOM 4454 C CB . PHE C 1 184 ? 11.546 17.341 -49.272 1.00 34.40 ? 165 PHE C CB 1 ATOM 4455 C CG . PHE C 1 184 ? 10.280 16.658 -48.836 1.00 31.34 ? 165 PHE C CG 1 ATOM 4456 C CD1 . PHE C 1 184 ? 9.137 17.400 -48.560 1.00 27.11 ? 165 PHE C CD1 1 ATOM 4457 C CD2 . PHE C 1 184 ? 10.225 15.279 -48.703 1.00 35.40 ? 165 PHE C CD2 1 ATOM 4458 C CE1 . PHE C 1 184 ? 7.954 16.772 -48.157 1.00 27.10 ? 165 PHE C CE1 1 ATOM 4459 C CE2 . PHE C 1 184 ? 9.045 14.637 -48.308 1.00 33.59 ? 165 PHE C CE2 1 ATOM 4460 C CZ . PHE C 1 184 ? 7.907 15.387 -48.034 1.00 28.84 ? 165 PHE C CZ 1 ATOM 4461 N N . SER C 1 185 ? 12.029 17.029 -46.035 1.00 35.26 ? 166 SER C N 1 ATOM 4462 C CA . SER C 1 185 ? 12.492 16.242 -44.901 1.00 37.92 ? 166 SER C CA 1 ATOM 4463 C C . SER C 1 185 ? 12.669 14.758 -45.249 1.00 44.01 ? 166 SER C C 1 ATOM 4464 O O . SER C 1 185 ? 11.744 14.102 -45.766 1.00 40.80 ? 166 SER C O 1 ATOM 4465 C CB . SER C 1 185 ? 11.509 16.377 -43.736 1.00 30.83 ? 166 SER C CB 1 ATOM 4466 O OG . SER C 1 185 ? 11.951 15.630 -42.620 1.00 31.12 ? 166 SER C OG 1 ATOM 4467 N N . GLN C 1 186 ? 13.855 14.229 -44.950 1.00 40.14 ? 167 GLN C N 1 ATOM 4468 C CA . GLN C 1 186 ? 14.110 12.797 -45.107 1.00 40.04 ? 167 GLN C CA 1 ATOM 4469 C C . GLN C 1 186 ? 13.283 11.959 -44.128 1.00 40.87 ? 167 GLN C C 1 ATOM 4470 O O . GLN C 1 186 ? 13.082 10.768 -44.343 1.00 38.86 ? 167 GLN C O 1 ATOM 4471 C CB . GLN C 1 186 ? 15.591 12.494 -44.921 1.00 32.25 ? 167 GLN C CB 1 ATOM 4472 C CG . GLN C 1 186 ? 16.213 13.315 -43.814 1.00 43.74 ? 167 GLN C CG 1 ATOM 4473 C CD . GLN C 1 186 ? 17.656 12.920 -43.499 1.00 56.54 ? 167 GLN C CD 1 ATOM 4474 O OE1 . GLN C 1 186 ? 18.048 11.749 -43.634 1.00 51.77 ? 167 GLN C OE1 1 ATOM 4475 N NE2 . GLN C 1 186 ? 18.455 13.904 -43.065 1.00 57.54 ? 167 GLN C NE2 1 ATOM 4476 N N . TYR C 1 187 ? 12.787 12.583 -43.062 1.00 42.68 ? 168 TYR C N 1 ATOM 4477 C CA . TYR C 1 187 ? 12.078 11.832 -42.021 1.00 37.20 ? 168 TYR C CA 1 ATOM 4478 C C . TYR C 1 187 ? 10.557 11.773 -42.194 1.00 38.52 ? 168 TYR C C 1 ATOM 4479 O O . TYR C 1 187 ? 9.880 11.073 -41.442 1.00 36.67 ? 168 TYR C O 1 ATOM 4480 C CB . TYR C 1 187 ? 12.469 12.327 -40.624 1.00 35.53 ? 168 TYR C CB 1 ATOM 4481 C CG . TYR C 1 187 ? 13.965 12.310 -40.403 1.00 35.15 ? 168 TYR C CG 1 ATOM 4482 C CD1 . TYR C 1 187 ? 14.667 11.120 -40.424 1.00 37.38 ? 168 TYR C CD1 1 ATOM 4483 C CD2 . TYR C 1 187 ? 14.676 13.479 -40.192 1.00 35.19 ? 168 TYR C CD2 1 ATOM 4484 C CE1 . TYR C 1 187 ? 16.037 11.084 -40.236 1.00 36.59 ? 168 TYR C CE1 1 ATOM 4485 C CE2 . TYR C 1 187 ? 16.055 13.454 -40.000 1.00 45.53 ? 168 TYR C CE2 1 ATOM 4486 C CZ . TYR C 1 187 ? 16.728 12.247 -40.022 1.00 39.30 ? 168 TYR C CZ 1 ATOM 4487 O OH . TYR C 1 187 ? 18.096 12.199 -39.844 1.00 38.52 ? 168 TYR C OH 1 ATOM 4488 N N . SER C 1 188 ? 10.027 12.486 -43.188 1.00 38.59 ? 169 SER C N 1 ATOM 4489 C CA . SER C 1 188 ? 8.616 12.358 -43.562 1.00 28.73 ? 169 SER C CA 1 ATOM 4490 C C . SER C 1 188 ? 8.256 10.910 -43.943 1.00 36.81 ? 169 SER C C 1 ATOM 4491 O O . SER C 1 188 ? 9.111 10.143 -44.412 1.00 39.79 ? 169 SER C O 1 ATOM 4492 C CB . SER C 1 188 ? 8.308 13.286 -44.744 1.00 32.43 ? 169 SER C CB 1 ATOM 4493 O OG . SER C 1 188 ? 6.926 13.273 -45.049 1.00 33.89 ? 169 SER C OG 1 ATOM 4494 N N . ARG C 1 189 ? 6.993 10.534 -43.750 1.00 35.40 ? 170 ARG C N 1 ATOM 4495 C CA . ARG C 1 189 ? 6.524 9.221 -44.198 1.00 30.34 ? 170 ARG C CA 1 ATOM 4496 C C . ARG C 1 189 ? 6.299 9.200 -45.713 1.00 34.70 ? 170 ARG C C 1 ATOM 4497 O O . ARG C 1 189 ? 5.907 8.175 -46.277 1.00 37.10 ? 170 ARG C O 1 ATOM 4498 C CB . ARG C 1 189 ? 5.218 8.821 -43.500 1.00 24.54 ? 170 ARG C CB 1 ATOM 4499 C CG . ARG C 1 189 ? 5.323 8.666 -42.004 1.00 39.88 ? 170 ARG C CG 1 ATOM 4500 C CD . ARG C 1 189 ? 4.503 7.475 -41.517 1.00 49.91 ? 170 ARG C CD 1 ATOM 4501 N NE . ARG C 1 189 ? 3.073 7.612 -41.782 1.00 54.06 ? 170 ARG C NE 1 ATOM 4502 C CZ . ARG C 1 189 ? 2.224 6.588 -41.873 1.00 64.46 ? 170 ARG C CZ 1 ATOM 4503 N NH1 . ARG C 1 189 ? 2.659 5.339 -41.732 1.00 74.60 ? 170 ARG C NH1 1 ATOM 4504 N NH2 . ARG C 1 189 ? 0.939 6.810 -42.117 1.00 64.01 ? 170 ARG C NH2 1 ATOM 4505 N N . PHE C 1 190 ? 6.514 10.336 -46.366 1.00 28.95 ? 171 PHE C N 1 ATOM 4506 C CA . PHE C 1 190 ? 6.196 10.452 -47.782 1.00 29.84 ? 171 PHE C CA 1 ATOM 4507 C C . PHE C 1 190 ? 7.395 10.986 -48.538 1.00 33.59 ? 171 PHE C C 1 ATOM 4508 O O . PHE C 1 190 ? 8.345 11.486 -47.927 1.00 36.22 ? 171 PHE C O 1 ATOM 4509 C CB . PHE C 1 190 ? 5.007 11.389 -48.014 1.00 29.32 ? 171 PHE C CB 1 ATOM 4510 C CG . PHE C 1 190 ? 3.792 11.043 -47.221 1.00 25.81 ? 171 PHE C CG 1 ATOM 4511 C CD1 . PHE C 1 190 ? 3.673 11.440 -45.881 1.00 27.69 ? 171 PHE C CD1 1 ATOM 4512 C CD2 . PHE C 1 190 ? 2.750 10.343 -47.809 1.00 28.13 ? 171 PHE C CD2 1 ATOM 4513 C CE1 . PHE C 1 190 ? 2.527 11.116 -45.129 1.00 26.95 ? 171 PHE C CE1 1 ATOM 4514 C CE2 . PHE C 1 190 ? 1.598 10.014 -47.080 1.00 30.82 ? 171 PHE C CE2 1 ATOM 4515 C CZ . PHE C 1 190 ? 1.488 10.402 -45.733 1.00 30.06 ? 171 PHE C CZ 1 ATOM 4516 N N . GLU C 1 191 ? 7.337 10.882 -49.865 1.00 36.72 ? 172 GLU C N 1 ATOM 4517 C CA . GLU C 1 191 ? 8.397 11.383 -50.736 1.00 36.85 ? 172 GLU C CA 1 ATOM 4518 C C . GLU C 1 191 ? 7.823 12.122 -51.952 1.00 34.54 ? 172 GLU C C 1 ATOM 4519 O O . GLU C 1 191 ? 6.712 11.829 -52.410 1.00 34.75 ? 172 GLU C O 1 ATOM 4520 C CB . GLU C 1 191 ? 9.360 10.253 -51.150 1.00 34.58 ? 172 GLU C CB 1 ATOM 4521 C CG . GLU C 1 191 ? 8.748 9.110 -51.979 1.00 42.24 ? 172 GLU C CG 1 ATOM 4522 C CD . GLU C 1 191 ? 9.730 7.922 -52.157 1.00 56.09 ? 172 GLU C CD 1 ATOM 4523 O OE1 . GLU C 1 191 ? 10.947 8.122 -51.890 1.00 53.68 ? 172 GLU C OE1 1 ATOM 4524 O OE2 . GLU C 1 191 ? 9.287 6.796 -52.547 1.00 38.03 ? 172 GLU C OE2 1 ATOM 4525 N N . ILE C 1 192 ? 8.576 13.094 -52.462 1.00 34.79 ? 173 ILE C N 1 ATOM 4526 C CA . ILE C 1 192 ? 8.118 13.869 -53.617 1.00 34.10 ? 173 ILE C CA 1 ATOM 4527 C C . ILE C 1 192 ? 8.631 13.272 -54.918 1.00 36.05 ? 173 ILE C C 1 ATOM 4528 O O . ILE C 1 192 ? 9.825 13.011 -55.058 1.00 36.23 ? 173 ILE C O 1 ATOM 4529 C CB . ILE C 1 192 ? 8.528 15.352 -53.510 1.00 35.60 ? 173 ILE C CB 1 ATOM 4530 C CG1 . ILE C 1 192 ? 7.903 15.963 -52.244 1.00 37.33 ? 173 ILE C CG1 1 ATOM 4531 C CG2 . ILE C 1 192 ? 8.103 16.109 -54.761 1.00 25.98 ? 173 ILE C CG2 1 ATOM 4532 C CD1 . ILE C 1 192 ? 8.221 17.399 -52.007 1.00 29.25 ? 173 ILE C CD1 1 ATOM 4533 N N . LEU C 1 193 ? 7.713 13.034 -55.855 1.00 39.27 ? 174 LEU C N 1 ATOM 4534 C CA . LEU C 1 193 ? 8.054 12.476 -57.164 1.00 36.37 ? 174 LEU C CA 1 ATOM 4535 C C . LEU C 1 193 ? 8.296 13.600 -58.163 1.00 35.67 ? 174 LEU C C 1 ATOM 4536 O O . LEU C 1 193 ? 9.235 13.546 -58.950 1.00 41.96 ? 174 LEU C O 1 ATOM 4537 C CB . LEU C 1 193 ? 6.953 11.537 -57.650 1.00 36.36 ? 174 LEU C CB 1 ATOM 4538 C CG . LEU C 1 193 ? 6.607 10.428 -56.643 1.00 35.39 ? 174 LEU C CG 1 ATOM 4539 C CD1 . LEU C 1 193 ? 5.462 9.538 -57.131 1.00 32.76 ? 174 LEU C CD1 1 ATOM 4540 C CD2 . LEU C 1 193 ? 7.838 9.597 -56.273 1.00 27.90 ? 174 LEU C CD2 1 ATOM 4541 N N . ASP C 1 194 ? 7.462 14.634 -58.102 1.00 41.27 ? 175 ASP C N 1 ATOM 4542 C CA . ASP C 1 194 ? 7.592 15.781 -58.999 1.00 42.55 ? 175 ASP C CA 1 ATOM 4543 C C . ASP C 1 194 ? 6.758 16.993 -58.560 1.00 42.65 ? 175 ASP C C 1 ATOM 4544 O O . ASP C 1 194 ? 5.701 16.849 -57.931 1.00 41.11 ? 175 ASP C O 1 ATOM 4545 C CB . ASP C 1 194 ? 7.197 15.387 -60.428 1.00 48.63 ? 175 ASP C CB 1 ATOM 4546 C CG . ASP C 1 194 ? 7.781 16.320 -61.476 1.00 61.03 ? 175 ASP C CG 1 ATOM 4547 O OD1 . ASP C 1 194 ? 8.937 16.769 -61.285 1.00 64.85 ? 175 ASP C OD1 1 ATOM 4548 O OD2 . ASP C 1 194 ? 7.087 16.602 -62.488 1.00 64.82 ? 175 ASP C OD2 1 ATOM 4549 N N . VAL C 1 195 ? 7.241 18.186 -58.903 1.00 39.36 ? 176 VAL C N 1 ATOM 4550 C CA . VAL C 1 195 ? 6.492 19.413 -58.667 1.00 35.76 ? 176 VAL C CA 1 ATOM 4551 C C . VAL C 1 195 ? 6.423 20.246 -59.940 1.00 40.57 ? 176 VAL C C 1 ATOM 4552 O O . VAL C 1 195 ? 7.456 20.652 -60.471 1.00 51.68 ? 176 VAL C O 1 ATOM 4553 C CB . VAL C 1 195 ? 7.142 20.285 -57.567 1.00 38.64 ? 176 VAL C CB 1 ATOM 4554 C CG1 . VAL C 1 195 ? 6.385 21.596 -57.429 1.00 44.34 ? 176 VAL C CG1 1 ATOM 4555 C CG2 . VAL C 1 195 ? 7.191 19.568 -56.232 1.00 29.92 ? 176 VAL C CG2 1 ATOM 4556 N N . THR C 1 196 ? 5.214 20.511 -60.423 1.00 34.68 ? 177 THR C N 1 ATOM 4557 C CA . THR C 1 196 ? 5.034 21.395 -61.584 1.00 39.60 ? 177 THR C CA 1 ATOM 4558 C C . THR C 1 196 ? 4.220 22.652 -61.249 1.00 39.22 ? 177 THR C C 1 ATOM 4559 O O . THR C 1 196 ? 3.397 22.644 -60.334 1.00 39.67 ? 177 THR C O 1 ATOM 4560 C CB . THR C 1 196 ? 4.380 20.660 -62.768 1.00 43.08 ? 177 THR C CB 1 ATOM 4561 O OG1 . THR C 1 196 ? 3.077 20.187 -62.389 1.00 45.42 ? 177 THR C OG1 1 ATOM 4562 C CG2 . THR C 1 196 ? 5.241 19.491 -63.197 1.00 48.99 ? 177 THR C CG2 1 ATOM 4563 N N . GLN C 1 197 ? 4.445 23.719 -62.007 1.00 38.82 ? 178 GLN C N 1 ATOM 4564 C CA . GLN C 1 197 ? 3.773 24.998 -61.780 1.00 37.36 ? 178 GLN C CA 1 ATOM 4565 C C . GLN C 1 197 ? 3.092 25.447 -63.079 1.00 41.62 ? 178 GLN C C 1 ATOM 4566 O O . GLN C 1 197 ? 3.664 25.290 -64.162 1.00 49.08 ? 178 GLN C O 1 ATOM 4567 C CB . GLN C 1 197 ? 4.797 26.063 -61.321 1.00 29.63 ? 178 GLN C CB 1 ATOM 4568 C CG . GLN C 1 197 ? 5.643 25.646 -60.104 1.00 37.79 ? 178 GLN C CG 1 ATOM 4569 C CD . GLN C 1 197 ? 6.189 26.833 -59.284 1.00 57.36 ? 178 GLN C CD 1 ATOM 4570 O OE1 . GLN C 1 197 ? 6.494 27.894 -59.834 1.00 58.51 ? 178 GLN C OE1 1 ATOM 4571 N NE2 . GLN C 1 197 ? 6.313 26.646 -57.956 1.00 51.69 ? 178 GLN C NE2 1 ATOM 4572 N N . LYS C 1 198 ? 1.881 25.992 -63.001 1.00 34.41 ? 179 LYS C N 1 ATOM 4573 C CA . LYS C 1 198 ? 1.336 26.687 -64.168 1.00 32.06 ? 179 LYS C CA 1 ATOM 4574 C C . LYS C 1 198 ? 0.484 27.886 -63.775 1.00 36.09 ? 179 LYS C C 1 ATOM 4575 O O . LYS C 1 198 ? -0.026 27.960 -62.656 1.00 39.17 ? 179 LYS C O 1 ATOM 4576 C CB . LYS C 1 198 ? 0.555 25.746 -65.070 1.00 33.37 ? 179 LYS C CB 1 ATOM 4577 C CG . LYS C 1 198 ? -0.914 25.672 -64.751 1.00 45.81 ? 179 LYS C CG 1 ATOM 4578 C CD . LYS C 1 198 ? -1.675 24.887 -65.826 1.00 49.73 ? 179 LYS C CD 1 ATOM 4579 C CE . LYS C 1 198 ? -3.105 24.596 -65.369 1.00 65.16 ? 179 LYS C CE 1 ATOM 4580 N NZ . LYS C 1 198 ? -3.869 23.786 -66.357 1.00 69.50 ? 179 LYS C NZ 1 ATOM 4581 N N . LYS C 1 199 ? 0.328 28.823 -64.702 1.00 33.60 ? 180 LYS C N 1 ATOM 4582 C CA . LYS C 1 199 ? -0.397 30.050 -64.407 1.00 35.77 ? 180 LYS C CA 1 ATOM 4583 C C . LYS C 1 199 ? -1.810 30.055 -65.004 1.00 35.86 ? 180 LYS C C 1 ATOM 4584 O O . LYS C 1 199 ? -1.994 29.683 -66.148 1.00 44.51 ? 180 LYS C O 1 ATOM 4585 C CB . LYS C 1 199 ? 0.404 31.253 -64.904 1.00 33.11 ? 180 LYS C CB 1 ATOM 4586 C CG . LYS C 1 199 ? -0.401 32.515 -65.002 1.00 39.71 ? 180 LYS C CG 1 ATOM 4587 C CD . LYS C 1 199 ? 0.454 33.663 -65.476 1.00 38.00 ? 180 LYS C CD 1 ATOM 4588 C CE . LYS C 1 199 ? -0.400 34.922 -65.621 1.00 45.14 ? 180 LYS C CE 1 ATOM 4589 N NZ . LYS C 1 199 ? 0.421 36.134 -65.933 1.00 54.23 ? 180 LYS C NZ 1 ATOM 4590 N N . ASN C 1 200 ? -2.808 30.465 -64.224 1.00 37.42 ? 181 ASN C N 1 ATOM 4591 C CA . ASN C 1 200 ? -4.168 30.587 -64.732 1.00 32.62 ? 181 ASN C CA 1 ATOM 4592 C C . ASN C 1 200 ? -4.681 32.019 -64.667 1.00 37.90 ? 181 ASN C C 1 ATOM 4593 O O . ASN C 1 200 ? -4.218 32.833 -63.865 1.00 42.45 ? 181 ASN C O 1 ATOM 4594 C CB . ASN C 1 200 ? -5.122 29.680 -63.962 1.00 38.46 ? 181 ASN C CB 1 ATOM 4595 C CG . ASN C 1 200 ? -4.629 28.246 -63.877 1.00 50.38 ? 181 ASN C CG 1 ATOM 4596 O OD1 . ASN C 1 200 ? -4.666 27.503 -64.862 1.00 55.65 ? 181 ASN C OD1 1 ATOM 4597 N ND2 . ASN C 1 200 ? -4.183 27.840 -62.686 1.00 53.55 ? 181 ASN C ND2 1 ATOM 4598 N N . SER C 1 201 ? -5.645 32.323 -65.523 1.00 37.71 ? 182 SER C N 1 ATOM 4599 C CA . SER C 1 201 ? -6.310 33.616 -65.498 1.00 34.24 ? 182 SER C CA 1 ATOM 4600 C C . SER C 1 201 ? -7.808 33.333 -65.539 1.00 33.33 ? 182 SER C C 1 ATOM 4601 O O . SER C 1 201 ? -8.311 32.810 -66.528 1.00 35.87 ? 182 SER C O 1 ATOM 4602 C CB . SER C 1 201 ? -5.872 34.471 -66.687 1.00 31.92 ? 182 SER C CB 1 ATOM 4603 O OG . SER C 1 201 ? -6.267 35.821 -66.525 1.00 34.42 ? 182 SER C OG 1 ATOM 4604 N N . VAL C 1 202 ? -8.506 33.661 -64.454 1.00 29.71 ? 183 VAL C N 1 ATOM 4605 C CA . VAL C 1 202 ? -9.886 33.245 -64.244 1.00 26.89 ? 183 VAL C CA 1 ATOM 4606 C C . VAL C 1 202 ? -10.830 34.439 -64.124 1.00 37.90 ? 183 VAL C C 1 ATOM 4607 O O . VAL C 1 202 ? -10.506 35.448 -63.479 1.00 34.68 ? 183 VAL C O 1 ATOM 4608 C CB . VAL C 1 202 ? -9.991 32.420 -62.943 1.00 34.25 ? 183 VAL C CB 1 ATOM 4609 C CG1 . VAL C 1 202 ? -11.450 32.048 -62.628 1.00 32.28 ? 183 VAL C CG1 1 ATOM 4610 C CG2 . VAL C 1 202 ? -9.108 31.194 -63.030 1.00 29.17 ? 183 VAL C CG2 1 ATOM 4611 N N . THR C 1 203 ? -12.005 34.326 -64.742 1.00 44.19 ? 184 THR C N 1 ATOM 4612 C CA . THR C 1 203 ? -13.053 35.323 -64.537 1.00 41.33 ? 184 THR C CA 1 ATOM 4613 C C . THR C 1 203 ? -14.171 34.779 -63.628 1.00 43.51 ? 184 THR C C 1 ATOM 4614 O O . THR C 1 203 ? -14.803 33.768 -63.926 1.00 50.11 ? 184 THR C O 1 ATOM 4615 C CB . THR C 1 203 ? -13.628 35.855 -65.868 1.00 34.83 ? 184 THR C CB 1 ATOM 4616 O OG1 . THR C 1 203 ? -12.629 36.642 -66.540 1.00 44.62 ? 184 THR C OG1 1 ATOM 4617 C CG2 . THR C 1 203 ? -14.843 36.734 -65.597 1.00 35.89 ? 184 THR C CG2 1 ATOM 4618 N N . TYR C 1 204 ? -14.410 35.451 -62.508 1.00 48.75 ? 185 TYR C N 1 ATOM 4619 C CA . TYR C 1 204 ? -15.452 35.025 -61.576 1.00 42.06 ? 185 TYR C CA 1 ATOM 4620 C C . TYR C 1 204 ? -16.789 35.700 -61.855 1.00 47.01 ? 185 TYR C C 1 ATOM 4621 O O . TYR C 1 204 ? -16.859 36.731 -62.535 1.00 52.43 ? 185 TYR C O 1 ATOM 4622 C CB . TYR C 1 204 ? -15.016 35.290 -60.136 1.00 34.81 ? 185 TYR C CB 1 ATOM 4623 C CG . TYR C 1 204 ? -13.794 34.503 -59.751 1.00 33.30 ? 185 TYR C CG 1 ATOM 4624 C CD1 . TYR C 1 204 ? -12.518 35.000 -59.992 1.00 37.42 ? 185 TYR C CD1 1 ATOM 4625 C CD2 . TYR C 1 204 ? -13.908 33.249 -59.168 1.00 32.97 ? 185 TYR C CD2 1 ATOM 4626 C CE1 . TYR C 1 204 ? -11.380 34.263 -59.652 1.00 37.03 ? 185 TYR C CE1 1 ATOM 4627 C CE2 . TYR C 1 204 ? -12.778 32.506 -58.815 1.00 31.82 ? 185 TYR C CE2 1 ATOM 4628 C CZ . TYR C 1 204 ? -11.516 33.017 -59.063 1.00 33.08 ? 185 TYR C CZ 1 ATOM 4629 O OH . TYR C 1 204 ? -10.382 32.295 -58.729 1.00 34.13 ? 185 TYR C OH 1 ATOM 4630 N N . SER C 1 205 ? -17.844 35.108 -61.306 1.00 43.88 ? 186 SER C N 1 ATOM 4631 C CA . SER C 1 205 ? -19.213 35.552 -61.550 1.00 52.87 ? 186 SER C CA 1 ATOM 4632 C C . SER C 1 205 ? -19.518 36.954 -61.030 1.00 50.55 ? 186 SER C C 1 ATOM 4633 O O . SER C 1 205 ? -20.504 37.572 -61.427 1.00 52.00 ? 186 SER C O 1 ATOM 4634 C CB . SER C 1 205 ? -20.199 34.550 -60.950 1.00 51.06 ? 186 SER C CB 1 ATOM 4635 O OG . SER C 1 205 ? -20.060 33.288 -61.573 1.00 64.70 ? 186 SER C OG 1 ATOM 4636 N N . CYS C 1 206 ? -18.668 37.454 -60.146 1.00 51.52 ? 187 CYS C N 1 ATOM 4637 C CA . CYS C 1 206 ? -18.906 38.744 -59.520 1.00 55.41 ? 187 CYS C CA 1 ATOM 4638 C C . CYS C 1 206 ? -18.489 39.939 -60.397 1.00 61.12 ? 187 CYS C C 1 ATOM 4639 O O . CYS C 1 206 ? -19.212 40.933 -60.453 1.00 71.01 ? 187 CYS C O 1 ATOM 4640 C CB . CYS C 1 206 ? -18.189 38.809 -58.168 1.00 61.20 ? 187 CYS C CB 1 ATOM 4641 S SG . CYS C 1 206 ? -16.400 39.152 -58.303 1.00 79.55 ? 187 CYS C SG 1 ATOM 4642 N N . CYS C 1 207 ? -17.343 39.837 -61.083 1.00 56.07 ? 188 CYS C N 1 ATOM 4643 C CA . CYS C 1 207 ? -16.714 40.990 -61.754 1.00 58.18 ? 188 CYS C CA 1 ATOM 4644 C C . CYS C 1 207 ? -16.285 40.671 -63.192 1.00 59.37 ? 188 CYS C C 1 ATOM 4645 O O . CYS C 1 207 ? -16.046 39.505 -63.526 1.00 58.00 ? 188 CYS C O 1 ATOM 4646 C CB . CYS C 1 207 ? -15.500 41.463 -60.931 1.00 57.57 ? 188 CYS C CB 1 ATOM 4647 S SG . CYS C 1 207 ? -15.375 40.629 -59.298 1.00 86.73 ? 188 CYS C SG 1 ATOM 4648 N N . PRO C 1 208 ? -16.176 41.706 -64.048 1.00 56.29 ? 189 PRO C N 1 ATOM 4649 C CA . PRO C 1 208 ? -15.775 41.534 -65.455 1.00 57.37 ? 189 PRO C CA 1 ATOM 4650 C C . PRO C 1 208 ? -14.263 41.432 -65.644 1.00 58.93 ? 189 PRO C C 1 ATOM 4651 O O . PRO C 1 208 ? -13.788 41.217 -66.764 1.00 62.57 ? 189 PRO C O 1 ATOM 4652 C CB . PRO C 1 208 ? -16.274 42.825 -66.113 1.00 61.58 ? 189 PRO C CB 1 ATOM 4653 C CG . PRO C 1 208 ? -16.162 43.842 -65.025 1.00 66.29 ? 189 PRO C CG 1 ATOM 4654 C CD . PRO C 1 208 ? -16.524 43.108 -63.746 1.00 60.55 ? 189 PRO C CD 1 ATOM 4655 N N . GLU C 1 209 ? -13.522 41.596 -64.553 1.00 57.15 ? 190 GLU C N 1 ATOM 4656 C CA . GLU C 1 209 ? -12.063 41.583 -64.591 1.00 52.43 ? 190 GLU C CA 1 ATOM 4657 C C . GLU C 1 209 ? -11.520 40.163 -64.388 1.00 44.38 ? 190 GLU C C 1 ATOM 4658 O O . GLU C 1 209 ? -12.192 39.306 -63.816 1.00 41.30 ? 190 GLU C O 1 ATOM 4659 C CB . GLU C 1 209 ? -11.526 42.515 -63.501 1.00 50.91 ? 190 GLU C CB 1 ATOM 4660 C CG . GLU C 1 209 ? -12.271 43.847 -63.388 1.00 57.44 ? 190 GLU C CG 1 ATOM 4661 C CD . GLU C 1 209 ? -11.841 44.843 -64.454 1.00 63.93 ? 190 GLU C CD 1 ATOM 4662 O OE1 . GLU C 1 209 ? -11.007 44.460 -65.309 1.00 68.63 ? 190 GLU C OE1 1 ATOM 4663 O OE2 . GLU C 1 209 ? -12.331 45.999 -64.432 1.00 56.46 ? 190 GLU C OE2 1 ATOM 4664 N N . ALA C 1 210 ? -10.303 39.911 -64.853 1.00 37.97 ? 191 ALA C N 1 ATOM 4665 C CA . ALA C 1 210 ? -9.681 38.609 -64.653 1.00 33.18 ? 191 ALA C CA 1 ATOM 4666 C C . ALA C 1 210 ? -8.778 38.624 -63.425 1.00 34.16 ? 191 ALA C C 1 ATOM 4667 O O . ALA C 1 210 ? -8.130 39.628 -63.143 1.00 38.81 ? 191 ALA C O 1 ATOM 4668 C CB . ALA C 1 210 ? -8.880 38.217 -65.870 1.00 38.93 ? 191 ALA C CB 1 ATOM 4669 N N . TYR C 1 211 ? -8.726 37.506 -62.704 1.00 35.84 ? 192 TYR C N 1 ATOM 4670 C CA . TYR C 1 211 ? -7.831 37.366 -61.549 1.00 31.81 ? 192 TYR C CA 1 ATOM 4671 C C . TYR C 1 211 ? -6.797 36.272 -61.793 1.00 31.65 ? 192 TYR C C 1 ATOM 4672 O O . TYR C 1 211 ? -7.149 35.111 -62.017 1.00 33.87 ? 192 TYR C O 1 ATOM 4673 C CB . TYR C 1 211 ? -8.640 37.054 -60.292 1.00 25.77 ? 192 TYR C CB 1 ATOM 4674 C CG . TYR C 1 211 ? -9.478 38.210 -59.829 1.00 28.11 ? 192 TYR C CG 1 ATOM 4675 C CD1 . TYR C 1 211 ? -10.653 38.548 -60.475 1.00 27.32 ? 192 TYR C CD1 1 ATOM 4676 C CD2 . TYR C 1 211 ? -9.086 38.975 -58.748 1.00 32.33 ? 192 TYR C CD2 1 ATOM 4677 C CE1 . TYR C 1 211 ? -11.418 39.624 -60.053 1.00 34.61 ? 192 TYR C CE1 1 ATOM 4678 C CE2 . TYR C 1 211 ? -9.841 40.053 -58.311 1.00 30.29 ? 192 TYR C CE2 1 ATOM 4679 C CZ . TYR C 1 211 ? -11.010 40.377 -58.965 1.00 34.83 ? 192 TYR C CZ 1 ATOM 4680 O OH . TYR C 1 211 ? -11.772 41.459 -58.537 1.00 35.60 ? 192 TYR C OH 1 ATOM 4681 N N . GLU C 1 212 ? -5.522 36.631 -61.756 1.00 29.55 ? 193 GLU C N 1 ATOM 4682 C CA . GLU C 1 212 ? -4.476 35.630 -61.953 1.00 34.12 ? 193 GLU C CA 1 ATOM 4683 C C . GLU C 1 212 ? -4.178 34.792 -60.706 1.00 33.53 ? 193 GLU C C 1 ATOM 4684 O O . GLU C 1 212 ? -4.276 35.268 -59.570 1.00 35.33 ? 193 GLU C O 1 ATOM 4685 C CB . GLU C 1 212 ? -3.188 36.284 -62.441 1.00 37.65 ? 193 GLU C CB 1 ATOM 4686 C CG . GLU C 1 212 ? -3.349 37.105 -63.704 1.00 39.20 ? 193 GLU C CG 1 ATOM 4687 C CD . GLU C 1 212 ? -2.018 37.609 -64.244 1.00 44.24 ? 193 GLU C CD 1 ATOM 4688 O OE1 . GLU C 1 212 ? -0.970 37.316 -63.626 1.00 44.66 ? 193 GLU C OE1 1 ATOM 4689 O OE2 . GLU C 1 212 ? -2.019 38.296 -65.291 1.00 53.83 ? 193 GLU C OE2 1 ATOM 4690 N N . ASP C 1 213 ? -3.800 33.542 -60.937 1.00 28.62 ? 194 ASP C N 1 ATOM 4691 C CA . ASP C 1 213 ? -3.311 32.672 -59.874 1.00 30.71 ? 194 ASP C CA 1 ATOM 4692 C C . ASP C 1 213 ? -2.257 31.703 -60.396 1.00 34.59 ? 194 ASP C C 1 ATOM 4693 O O . ASP C 1 213 ? -2.083 31.530 -61.599 1.00 34.92 ? 194 ASP C O 1 ATOM 4694 C CB . ASP C 1 213 ? -4.450 31.877 -59.233 1.00 39.57 ? 194 ASP C CB 1 ATOM 4695 C CG . ASP C 1 213 ? -5.273 31.086 -60.261 1.00 50.08 ? 194 ASP C CG 1 ATOM 4696 O OD1 . ASP C 1 213 ? -4.863 29.946 -60.630 1.00 49.42 ? 194 ASP C OD1 1 ATOM 4697 O OD2 . ASP C 1 213 ? -6.336 31.614 -60.690 1.00 50.69 ? 194 ASP C OD2 1 ATOM 4698 N N . VAL C 1 214 ? -1.553 31.070 -59.476 1.00 30.63 ? 195 VAL C N 1 ATOM 4699 C CA . VAL C 1 214 ? -0.617 30.039 -59.831 1.00 25.97 ? 195 VAL C CA 1 ATOM 4700 C C . VAL C 1 214 ? -1.135 28.743 -59.240 1.00 32.47 ? 195 VAL C C 1 ATOM 4701 O O . VAL C 1 214 ? -1.598 28.705 -58.095 1.00 27.01 ? 195 VAL C O 1 ATOM 4702 C CB . VAL C 1 214 ? 0.779 30.369 -59.298 1.00 25.14 ? 195 VAL C CB 1 ATOM 4703 C CG1 . VAL C 1 214 ? 1.732 29.190 -59.457 1.00 27.24 ? 195 VAL C CG1 1 ATOM 4704 C CG2 . VAL C 1 214 ? 1.320 31.584 -60.024 1.00 36.30 ? 195 VAL C CG2 1 ATOM 4705 N N . GLU C 1 215 ? -1.078 27.687 -60.047 1.00 36.36 ? 196 GLU C N 1 ATOM 4706 C CA . GLU C 1 215 ? -1.451 26.342 -59.616 1.00 34.59 ? 196 GLU C CA 1 ATOM 4707 C C . GLU C 1 215 ? -0.193 25.495 -59.467 1.00 32.84 ? 196 GLU C C 1 ATOM 4708 O O . GLU C 1 215 ? 0.578 25.344 -60.413 1.00 34.88 ? 196 GLU C O 1 ATOM 4709 C CB . GLU C 1 215 ? -2.377 25.710 -60.649 1.00 44.41 ? 196 GLU C CB 1 ATOM 4710 C CG . GLU C 1 215 ? -3.671 25.126 -60.093 1.00 51.62 ? 196 GLU C CG 1 ATOM 4711 C CD . GLU C 1 215 ? -4.616 24.608 -61.196 1.00 66.94 ? 196 GLU C CD 1 ATOM 4712 O OE1 . GLU C 1 215 ? -4.152 23.853 -62.093 1.00 65.86 ? 196 GLU C OE1 1 ATOM 4713 O OE2 . GLU C 1 215 ? -5.820 24.961 -61.161 1.00 61.98 ? 196 GLU C OE2 1 ATOM 4714 N N . VAL C 1 216 ? 0.025 24.952 -58.274 1.00 33.12 ? 197 VAL C N 1 ATOM 4715 C CA . VAL C 1 216 ? 1.214 24.149 -58.028 1.00 28.67 ? 197 VAL C CA 1 ATOM 4716 C C . VAL C 1 216 ? 0.813 22.697 -57.828 1.00 29.03 ? 197 VAL C C 1 ATOM 4717 O O . VAL C 1 216 ? 0.097 22.382 -56.879 1.00 24.64 ? 197 VAL C O 1 ATOM 4718 C CB . VAL C 1 216 ? 2.013 24.652 -56.806 1.00 26.67 ? 197 VAL C CB 1 ATOM 4719 C CG1 . VAL C 1 216 ? 3.190 23.724 -56.517 1.00 29.49 ? 197 VAL C CG1 1 ATOM 4720 C CG2 . VAL C 1 216 ? 2.496 26.064 -57.035 1.00 24.08 ? 197 VAL C CG2 1 ATOM 4721 N N . SER C 1 217 ? 1.280 21.822 -58.726 1.00 36.53 ? 198 SER C N 1 ATOM 4722 C CA . SER C 1 217 ? 0.950 20.394 -58.687 1.00 30.60 ? 198 SER C CA 1 ATOM 4723 C C . SER C 1 217 ? 2.027 19.596 -57.988 1.00 27.52 ? 198 SER C C 1 ATOM 4724 O O . SER C 1 217 ? 3.183 19.569 -58.410 1.00 32.75 ? 198 SER C O 1 ATOM 4725 C CB . SER C 1 217 ? 0.746 19.845 -60.093 1.00 31.42 ? 198 SER C CB 1 ATOM 4726 O OG . SER C 1 217 ? -0.260 20.572 -60.756 1.00 46.57 ? 198 SER C OG 1 ATOM 4727 N N . LEU C 1 218 ? 1.632 18.932 -56.917 1.00 24.90 ? 199 LEU C N 1 ATOM 4728 C CA . LEU C 1 218 ? 2.574 18.215 -56.088 1.00 26.95 ? 199 LEU C CA 1 ATOM 4729 C C . LEU C 1 218 ? 2.316 16.725 -56.224 1.00 33.98 ? 199 LEU C C 1 ATOM 4730 O O . LEU C 1 218 ? 1.292 16.210 -55.742 1.00 34.20 ? 199 LEU C O 1 ATOM 4731 C CB . LEU C 1 218 ? 2.435 18.658 -54.628 1.00 23.73 ? 199 LEU C CB 1 ATOM 4732 C CG . LEU C 1 218 ? 3.196 17.798 -53.623 1.00 29.50 ? 199 LEU C CG 1 ATOM 4733 C CD1 . LEU C 1 218 ? 4.694 17.859 -53.889 1.00 31.73 ? 199 LEU C CD1 1 ATOM 4734 C CD2 . LEU C 1 218 ? 2.872 18.195 -52.193 1.00 25.43 ? 199 LEU C CD2 1 ATOM 4735 N N . ASN C 1 219 ? 3.240 16.031 -56.883 1.00 32.68 ? 200 ASN C N 1 ATOM 4736 C CA . ASN C 1 219 ? 3.118 14.585 -57.054 1.00 37.78 ? 200 ASN C CA 1 ATOM 4737 C C . ASN C 1 219 ? 3.932 13.828 -55.994 1.00 35.43 ? 200 ASN C C 1 ATOM 4738 O O . ASN C 1 219 ? 5.161 13.912 -55.970 1.00 35.85 ? 200 ASN C O 1 ATOM 4739 C CB . ASN C 1 219 ? 3.522 14.183 -58.477 1.00 35.35 ? 200 ASN C CB 1 ATOM 4740 C CG . ASN C 1 219 ? 3.277 12.719 -58.757 1.00 40.32 ? 200 ASN C CG 1 ATOM 4741 O OD1 . ASN C 1 219 ? 4.110 12.047 -59.372 1.00 51.24 ? 200 ASN C OD1 1 ATOM 4742 N ND2 . ASN C 1 219 ? 2.134 12.208 -58.295 1.00 38.94 ? 200 ASN C ND2 1 ATOM 4743 N N . PHE C 1 220 ? 3.245 13.102 -55.114 1.00 31.03 ? 201 PHE C N 1 ATOM 4744 C CA . PHE C 1 220 ? 3.902 12.464 -53.963 1.00 36.35 ? 201 PHE C CA 1 ATOM 4745 C C . PHE C 1 220 ? 3.265 11.105 -53.605 1.00 35.28 ? 201 PHE C C 1 ATOM 4746 O O . PHE C 1 220 ? 2.104 10.830 -53.957 1.00 35.87 ? 201 PHE C O 1 ATOM 4747 C CB . PHE C 1 220 ? 3.844 13.395 -52.741 1.00 29.52 ? 201 PHE C CB 1 ATOM 4748 C CG . PHE C 1 220 ? 2.472 13.502 -52.132 1.00 28.73 ? 201 PHE C CG 1 ATOM 4749 C CD1 . PHE C 1 220 ? 1.445 14.171 -52.801 1.00 26.44 ? 201 PHE C CD1 1 ATOM 4750 C CD2 . PHE C 1 220 ? 2.195 12.919 -50.898 1.00 30.47 ? 201 PHE C CD2 1 ATOM 4751 C CE1 . PHE C 1 220 ? 0.155 14.256 -52.239 1.00 28.49 ? 201 PHE C CE1 1 ATOM 4752 C CE2 . PHE C 1 220 ? 0.907 13.008 -50.323 1.00 30.39 ? 201 PHE C CE2 1 ATOM 4753 C CZ . PHE C 1 220 ? -0.108 13.680 -50.992 1.00 22.26 ? 201 PHE C CZ 1 ATOM 4754 N N . ARG C 1 221 ? 4.012 10.262 -52.895 1.00 25.93 ? 202 ARG C N 1 ATOM 4755 C CA . ARG C 1 221 ? 3.463 8.990 -52.435 1.00 31.60 ? 202 ARG C CA 1 ATOM 4756 C C . ARG C 1 221 ? 4.050 8.570 -51.102 1.00 34.84 ? 202 ARG C C 1 ATOM 4757 O O . ARG C 1 221 ? 5.039 9.153 -50.644 1.00 34.60 ? 202 ARG C O 1 ATOM 4758 C CB . ARG C 1 221 ? 3.724 7.877 -53.453 1.00 40.44 ? 202 ARG C CB 1 ATOM 4759 C CG . ARG C 1 221 ? 5.201 7.635 -53.699 1.00 38.31 ? 202 ARG C CG 1 ATOM 4760 C CD . ARG C 1 221 ? 5.513 6.176 -53.960 1.00 36.29 ? 202 ARG C CD 1 ATOM 4761 N NE . ARG C 1 221 ? 6.942 6.013 -54.205 1.00 40.16 ? 202 ARG C NE 1 ATOM 4762 C CZ . ARG C 1 221 ? 7.483 5.829 -55.402 1.00 32.25 ? 202 ARG C CZ 1 ATOM 4763 N NH1 . ARG C 1 221 ? 6.706 5.738 -56.469 1.00 33.06 ? 202 ARG C NH1 1 ATOM 4764 N NH2 . ARG C 1 221 ? 8.801 5.710 -55.519 1.00 30.84 ? 202 ARG C NH2 1 ATOM 4765 N N . LYS C 1 222 ? 3.440 7.545 -50.499 1.00 34.68 ? 203 LYS C N 1 ATOM 4766 C CA . LYS C 1 222 ? 3.943 6.940 -49.268 1.00 31.74 ? 203 LYS C CA 1 ATOM 4767 C C . LYS C 1 222 ? 5.194 6.111 -49.564 1.00 32.62 ? 203 LYS C C 1 ATOM 4768 O O . LYS C 1 222 ? 5.287 5.466 -50.613 1.00 30.00 ? 203 LYS C O 1 ATOM 4769 C CB . LYS C 1 222 ? 2.867 6.069 -48.630 1.00 36.66 ? 203 LYS C CB 1 ATOM 4770 C CG . LYS C 1 222 ? 3.224 5.554 -47.244 1.00 48.82 ? 203 LYS C CG 1 ATOM 4771 C CD . LYS C 1 222 ? 2.038 4.806 -46.650 1.00 67.40 ? 203 LYS C CD 1 ATOM 4772 C CE . LYS C 1 222 ? 2.332 4.255 -45.262 1.00 86.76 ? 203 LYS C CE 1 ATOM 4773 N NZ . LYS C 1 222 ? 1.156 3.487 -44.732 1.00 80.94 ? 203 LYS C NZ 1 ATOM 4774 N N . LYS C 1 223 ? 6.165 6.161 -48.655 1.00 31.63 ? 204 LYS C N 1 ATOM 4775 C CA . LYS C 1 223 ? 7.417 5.423 -48.803 1.00 30.99 ? 204 LYS C CA 1 ATOM 4776 C C . LYS C 1 223 ? 7.234 3.921 -48.545 1.00 47.78 ? 204 LYS C C 1 ATOM 4777 O O . LYS C 1 223 ? 6.315 3.515 -47.807 1.00 50.80 ? 204 LYS C O 1 ATOM 4778 C CB . LYS C 1 223 ? 8.448 5.949 -47.812 1.00 34.36 ? 204 LYS C CB 1 ATOM 4779 C CG . LYS C 1 223 ? 9.088 7.278 -48.143 1.00 34.04 ? 204 LYS C CG 1 ATOM 4780 C CD . LYS C 1 223 ? 9.910 7.748 -46.936 1.00 34.95 ? 204 LYS C CD 1 ATOM 4781 C CE . LYS C 1 223 ? 11.024 8.707 -47.320 1.00 41.16 ? 204 LYS C CE 1 ATOM 4782 N NZ . LYS C 1 223 ? 11.943 8.936 -46.165 1.00 46.03 ? 204 LYS C NZ 1 ATOM 4783 N N . GLY C 1 224 ? 8.129 3.113 -49.129 1.00 43.18 ? 205 GLY C N 1 ATOM 4784 C CA . GLY C 1 224 ? 8.146 1.670 -48.919 1.00 44.34 ? 205 GLY C CA 1 ATOM 4785 C C . GLY C 1 224 ? 9.493 1.149 -48.436 1.00 56.65 ? 205 GLY C C 1 ATOM 4786 O O . GLY C 1 224 ? 9.594 0.072 -47.838 1.00 59.91 ? 205 GLY C O 1 ATOM 4787 N N . LEU D 1 20 ? -6.069 62.696 -58.543 1.00 44.00 ? 1 LEU D N 1 ATOM 4788 C CA . LEU D 1 20 ? -6.070 61.761 -57.428 1.00 37.09 ? 1 LEU D CA 1 ATOM 4789 C C . LEU D 1 20 ? -5.427 60.469 -57.845 1.00 39.56 ? 1 LEU D C 1 ATOM 4790 O O . LEU D 1 20 ? -5.772 59.922 -58.892 1.00 48.40 ? 1 LEU D O 1 ATOM 4791 C CB . LEU D 1 20 ? -7.499 61.450 -56.973 1.00 38.05 ? 1 LEU D CB 1 ATOM 4792 C CG . LEU D 1 20 ? -8.217 62.468 -56.095 1.00 27.10 ? 1 LEU D CG 1 ATOM 4793 C CD1 . LEU D 1 20 ? -9.489 61.853 -55.594 1.00 32.15 ? 1 LEU D CD1 1 ATOM 4794 C CD2 . LEU D 1 20 ? -7.340 62.888 -54.929 1.00 29.27 ? 1 LEU D CD2 1 ATOM 4795 N N . ASP D 1 21 ? -4.493 59.979 -57.032 1.00 39.67 ? 2 ASP D N 1 ATOM 4796 C CA . ASP D 1 21 ? -3.944 58.637 -57.236 1.00 46.32 ? 2 ASP D CA 1 ATOM 4797 C C . ASP D 1 21 ? -4.373 57.739 -56.084 1.00 38.48 ? 2 ASP D C 1 ATOM 4798 O O . ASP D 1 21 ? -5.028 58.213 -55.150 1.00 34.02 ? 2 ASP D O 1 ATOM 4799 C CB . ASP D 1 21 ? -2.417 58.668 -57.393 1.00 40.85 ? 2 ASP D CB 1 ATOM 4800 C CG . ASP D 1 21 ? -1.738 59.574 -56.377 1.00 48.27 ? 2 ASP D CG 1 ATOM 4801 O OD1 . ASP D 1 21 ? -2.182 59.598 -55.208 1.00 49.96 ? 2 ASP D OD1 1 ATOM 4802 O OD2 . ASP D 1 21 ? -0.755 60.265 -56.748 1.00 56.51 ? 2 ASP D OD2 1 ATOM 4803 N N . ARG D 1 22 ? -4.019 56.457 -56.154 1.00 31.35 ? 3 ARG D N 1 ATOM 4804 C CA . ARG D 1 22 ? -4.408 55.536 -55.099 1.00 36.85 ? 3 ARG D CA 1 ATOM 4805 C C . ARG D 1 22 ? -3.937 56.021 -53.740 1.00 33.14 ? 3 ARG D C 1 ATOM 4806 O O . ARG D 1 22 ? -4.683 55.926 -52.749 1.00 31.61 ? 3 ARG D O 1 ATOM 4807 C CB . ARG D 1 22 ? -3.901 54.114 -55.363 1.00 36.29 ? 3 ARG D CB 1 ATOM 4808 C CG . ARG D 1 22 ? -4.743 53.350 -56.336 1.00 33.69 ? 3 ARG D CG 1 ATOM 4809 C CD . ARG D 1 22 ? -4.201 51.964 -56.548 1.00 38.59 ? 3 ARG D CD 1 ATOM 4810 N NE . ARG D 1 22 ? -5.024 51.238 -57.508 1.00 44.47 ? 3 ARG D NE 1 ATOM 4811 C CZ . ARG D 1 22 ? -4.892 51.340 -58.826 1.00 47.77 ? 3 ARG D CZ 1 ATOM 4812 N NH1 . ARG D 1 22 ? -3.958 52.136 -59.345 1.00 42.08 ? 3 ARG D NH1 1 ATOM 4813 N NH2 . ARG D 1 22 ? -5.692 50.640 -59.619 1.00 51.26 ? 3 ARG D NH2 1 ATOM 4814 N N . ALA D 1 23 ? -2.718 56.553 -53.697 1.00 24.79 ? 4 ALA D N 1 ATOM 4815 C CA . ALA D 1 23 ? -2.139 56.950 -52.421 1.00 24.85 ? 4 ALA D CA 1 ATOM 4816 C C . ALA D 1 23 ? -3.011 58.015 -51.759 1.00 33.20 ? 4 ALA D C 1 ATOM 4817 O O . ALA D 1 23 ? -3.277 57.965 -50.547 1.00 33.50 ? 4 ALA D O 1 ATOM 4818 C CB . ALA D 1 23 ? -0.752 57.440 -52.601 1.00 19.79 ? 4 ALA D CB 1 ATOM 4819 N N . ASP D 1 24 ? -3.473 58.963 -52.567 1.00 33.52 ? 5 ASP D N 1 ATOM 4820 C CA . ASP D 1 24 ? -4.318 60.054 -52.083 1.00 33.94 ? 5 ASP D CA 1 ATOM 4821 C C . ASP D 1 24 ? -5.696 59.566 -51.567 1.00 32.64 ? 5 ASP D C 1 ATOM 4822 O O . ASP D 1 24 ? -6.162 59.985 -50.496 1.00 29.62 ? 5 ASP D O 1 ATOM 4823 C CB . ASP D 1 24 ? -4.475 61.119 -53.182 1.00 33.90 ? 5 ASP D CB 1 ATOM 4824 C CG . ASP D 1 24 ? -3.185 61.908 -53.430 1.00 51.26 ? 5 ASP D CG 1 ATOM 4825 O OD1 . ASP D 1 24 ? -2.416 62.116 -52.457 1.00 52.26 ? 5 ASP D OD1 1 ATOM 4826 O OD2 . ASP D 1 24 ? -2.948 62.323 -54.598 1.00 55.82 ? 5 ASP D OD2 1 ATOM 4827 N N . ILE D 1 25 ? -6.332 58.675 -52.325 1.00 28.94 ? 6 ILE D N 1 ATOM 4828 C CA . ILE D 1 25 ? -7.649 58.156 -51.963 1.00 25.06 ? 6 ILE D CA 1 ATOM 4829 C C . ILE D 1 25 ? -7.621 57.372 -50.653 1.00 29.57 ? 6 ILE D C 1 ATOM 4830 O O . ILE D 1 25 ? -8.447 57.606 -49.767 1.00 28.80 ? 6 ILE D O 1 ATOM 4831 C CB . ILE D 1 25 ? -8.219 57.245 -53.068 1.00 25.75 ? 6 ILE D CB 1 ATOM 4832 C CG1 . ILE D 1 25 ? -8.453 58.040 -54.350 1.00 22.71 ? 6 ILE D CG1 1 ATOM 4833 C CG2 . ILE D 1 25 ? -9.506 56.555 -52.604 1.00 20.95 ? 6 ILE D CG2 1 ATOM 4834 C CD1 . ILE D 1 25 ? -8.690 57.157 -55.566 1.00 32.34 ? 6 ILE D CD1 1 ATOM 4835 N N . LEU D 1 26 ? -6.671 56.442 -50.537 1.00 29.27 ? 7 LEU D N 1 ATOM 4836 C CA . LEU D 1 26 ? -6.518 55.647 -49.315 1.00 23.82 ? 7 LEU D CA 1 ATOM 4837 C C . LEU D 1 26 ? -6.181 56.526 -48.112 1.00 28.12 ? 7 LEU D C 1 ATOM 4838 O O . LEU D 1 26 ? -6.601 56.235 -46.990 1.00 29.58 ? 7 LEU D O 1 ATOM 4839 C CB . LEU D 1 26 ? -5.475 54.550 -49.507 1.00 23.30 ? 7 LEU D CB 1 ATOM 4840 C CG . LEU D 1 26 ? -5.916 53.526 -50.555 1.00 23.77 ? 7 LEU D CG 1 ATOM 4841 C CD1 . LEU D 1 26 ? -4.741 52.777 -51.166 1.00 23.08 ? 7 LEU D CD1 1 ATOM 4842 C CD2 . LEU D 1 26 ? -6.906 52.556 -49.935 1.00 21.55 ? 7 LEU D CD2 1 ATOM 4843 N N . TYR D 1 27 ? -5.442 57.611 -48.359 1.00 27.36 ? 8 TYR D N 1 ATOM 4844 C CA . TYR D 1 27 ? -5.126 58.579 -47.320 1.00 22.35 ? 8 TYR D CA 1 ATOM 4845 C C . TYR D 1 27 ? -6.398 59.243 -46.815 1.00 25.29 ? 8 TYR D C 1 ATOM 4846 O O . TYR D 1 27 ? -6.680 59.218 -45.623 1.00 23.40 ? 8 TYR D O 1 ATOM 4847 C CB . TYR D 1 27 ? -4.159 59.636 -47.832 1.00 27.22 ? 8 TYR D CB 1 ATOM 4848 C CG . TYR D 1 27 ? -3.806 60.680 -46.797 1.00 30.68 ? 8 TYR D CG 1 ATOM 4849 C CD1 . TYR D 1 27 ? -2.922 60.389 -45.766 1.00 30.95 ? 8 TYR D CD1 1 ATOM 4850 C CD2 . TYR D 1 27 ? -4.359 61.961 -46.853 1.00 31.69 ? 8 TYR D CD2 1 ATOM 4851 C CE1 . TYR D 1 27 ? -2.599 61.345 -44.810 1.00 40.90 ? 8 TYR D CE1 1 ATOM 4852 C CE2 . TYR D 1 27 ? -4.045 62.922 -45.902 1.00 34.60 ? 8 TYR D CE2 1 ATOM 4853 C CZ . TYR D 1 27 ? -3.164 62.605 -44.884 1.00 41.43 ? 8 TYR D CZ 1 ATOM 4854 O OH . TYR D 1 27 ? -2.836 63.547 -43.947 1.00 50.40 ? 8 TYR D OH 1 ATOM 4855 N N . ASN D 1 28 ? -7.168 59.833 -47.722 1.00 23.69 ? 9 ASN D N 1 ATOM 4856 C CA . ASN D 1 28 ? -8.435 60.443 -47.340 1.00 21.41 ? 9 ASN D CA 1 ATOM 4857 C C . ASN D 1 28 ? -9.351 59.471 -46.609 1.00 23.70 ? 9 ASN D C 1 ATOM 4858 O O . ASN D 1 28 ? -9.988 59.832 -45.620 1.00 23.25 ? 9 ASN D O 1 ATOM 4859 C CB . ASN D 1 28 ? -9.146 61.028 -48.562 1.00 22.97 ? 9 ASN D CB 1 ATOM 4860 C CG . ASN D 1 28 ? -8.332 62.119 -49.245 1.00 28.81 ? 9 ASN D CG 1 ATOM 4861 O OD1 . ASN D 1 28 ? -7.494 62.778 -48.604 1.00 32.20 ? 9 ASN D OD1 1 ATOM 4862 N ND2 . ASN D 1 28 ? -8.560 62.310 -50.557 1.00 22.06 ? 9 ASN D ND2 1 ATOM 4863 N N . ILE D 1 29 ? -9.408 58.232 -47.086 1.00 23.80 ? 10 ILE D N 1 ATOM 4864 C CA . ILE D 1 29 ? -10.266 57.242 -46.452 1.00 25.78 ? 10 ILE D CA 1 ATOM 4865 C C . ILE D 1 29 ? -9.818 56.963 -45.024 1.00 24.74 ? 10 ILE D C 1 ATOM 4866 O O . ILE D 1 29 ? -10.633 56.914 -44.112 1.00 24.31 ? 10 ILE D O 1 ATOM 4867 C CB . ILE D 1 29 ? -10.363 55.937 -47.262 1.00 23.13 ? 10 ILE D CB 1 ATOM 4868 C CG1 . ILE D 1 29 ? -11.135 56.193 -48.552 1.00 20.50 ? 10 ILE D CG1 1 ATOM 4869 C CG2 . ILE D 1 29 ? -11.057 54.850 -46.450 1.00 22.70 ? 10 ILE D CG2 1 ATOM 4870 C CD1 . ILE D 1 29 ? -11.312 54.967 -49.412 1.00 22.06 ? 10 ILE D CD1 1 ATOM 4871 N N . ARG D 1 30 ? -8.518 56.815 -44.827 1.00 22.01 ? 11 ARG D N 1 ATOM 4872 C CA . ARG D 1 30 ? -8.008 56.582 -43.487 1.00 24.82 ? 11 ARG D CA 1 ATOM 4873 C C . ARG D 1 30 ? -8.339 57.718 -42.507 1.00 30.86 ? 11 ARG D C 1 ATOM 4874 O O . ARG D 1 30 ? -8.582 57.468 -41.329 1.00 33.30 ? 11 ARG D O 1 ATOM 4875 C CB . ARG D 1 30 ? -6.504 56.313 -43.503 1.00 31.34 ? 11 ARG D CB 1 ATOM 4876 C CG . ARG D 1 30 ? -6.102 55.177 -42.580 1.00 46.87 ? 11 ARG D CG 1 ATOM 4877 C CD . ARG D 1 30 ? -4.746 55.407 -41.962 1.00 58.96 ? 11 ARG D CD 1 ATOM 4878 N NE . ARG D 1 30 ? -4.615 54.631 -40.731 1.00 81.76 ? 11 ARG D NE 1 ATOM 4879 C CZ . ARG D 1 30 ? -3.546 54.639 -39.940 1.00 84.31 ? 11 ARG D CZ 1 ATOM 4880 N NH1 . ARG D 1 30 ? -2.485 55.383 -40.248 1.00 74.76 ? 11 ARG D NH1 1 ATOM 4881 N NH2 . ARG D 1 30 ? -3.543 53.896 -38.840 1.00 80.51 ? 11 ARG D NH2 1 ATOM 4882 N N . GLN D 1 31 ? -8.387 58.953 -43.005 1.00 31.47 ? 12 GLN D N 1 ATOM 4883 C CA . GLN D 1 31 ? -8.571 60.133 -42.158 1.00 23.34 ? 12 GLN D CA 1 ATOM 4884 C C . GLN D 1 31 ? -10.019 60.506 -41.852 1.00 25.35 ? 12 GLN D C 1 ATOM 4885 O O . GLN D 1 31 ? -10.271 61.233 -40.902 1.00 33.43 ? 12 GLN D O 1 ATOM 4886 C CB . GLN D 1 31 ? -7.897 61.360 -42.781 1.00 29.34 ? 12 GLN D CB 1 ATOM 4887 C CG . GLN D 1 31 ? -6.398 61.244 -43.032 1.00 33.51 ? 12 GLN D CG 1 ATOM 4888 C CD . GLN D 1 31 ? -5.594 61.161 -41.750 1.00 40.35 ? 12 GLN D CD 1 ATOM 4889 O OE1 . GLN D 1 31 ? -6.087 61.483 -40.673 1.00 46.86 ? 12 GLN D OE1 1 ATOM 4890 N NE2 . GLN D 1 31 ? -4.345 60.729 -41.860 1.00 45.83 ? 12 GLN D NE2 1 ATOM 4891 N N . THR D 1 32 ? -10.967 60.037 -42.654 1.00 23.58 ? 13 THR D N 1 ATOM 4892 C CA . THR D 1 32 ? -12.331 60.561 -42.575 1.00 22.58 ? 13 THR D CA 1 ATOM 4893 C C . THR D 1 32 ? -13.426 59.495 -42.530 1.00 30.14 ? 13 THR D C 1 ATOM 4894 O O . THR D 1 32 ? -14.619 59.813 -42.615 1.00 31.88 ? 13 THR D O 1 ATOM 4895 C CB . THR D 1 32 ? -12.628 61.469 -43.796 1.00 29.56 ? 13 THR D CB 1 ATOM 4896 O OG1 . THR D 1 32 ? -12.515 60.701 -45.003 1.00 33.05 ? 13 THR D OG1 1 ATOM 4897 C CG2 . THR D 1 32 ? -11.674 62.646 -43.861 1.00 24.12 ? 13 THR D CG2 1 ATOM 4898 N N . SER D 1 33 ? -12.996 58.252 -42.475 1.00 41.49 ? 14 SER D N 1 ATOM 4899 C CA . SER D 1 33 ? -13.813 57.073 -42.733 1.00 36.06 ? 14 SER D CA 1 ATOM 4900 C C . SER D 1 33 ? -14.939 56.806 -41.767 1.00 34.83 ? 14 SER D C 1 ATOM 4901 O O . SER D 1 33 ? -16.012 56.473 -42.182 1.00 30.60 ? 14 SER D O 1 ATOM 4902 C CB . SER D 1 33 ? -12.906 55.862 -42.926 1.00 29.67 ? 14 SER D CB 1 ATOM 4903 O OG . SER D 1 33 ? -13.541 54.661 -42.627 1.00 38.04 ? 14 SER D OG 1 ATOM 4904 N N . ARG D 1 34 ? -14.711 57.004 -40.485 1.00 35.15 ? 15 ARG D N 1 ATOM 4905 C CA . ARG D 1 34 ? -15.713 56.687 -39.471 1.00 39.84 ? 15 ARG D CA 1 ATOM 4906 C C . ARG D 1 34 ? -16.222 55.251 -39.383 1.00 33.27 ? 15 ARG D C 1 ATOM 4907 O O . ARG D 1 34 ? -17.342 54.980 -39.645 1.00 31.23 ? 15 ARG D O 1 ATOM 4908 C CB . ARG D 1 34 ? -16.901 57.645 -39.517 1.00 34.74 ? 15 ARG D CB 1 ATOM 4909 C CG . ARG D 1 34 ? -16.610 59.123 -39.441 1.00 31.73 ? 15 ARG D CG 1 ATOM 4910 C CD . ARG D 1 34 ? -15.768 59.524 -38.259 1.00 43.91 ? 15 ARG D CD 1 ATOM 4911 N NE . ARG D 1 34 ? -16.393 59.215 -36.986 1.00 48.86 ? 15 ARG D NE 1 ATOM 4912 C CZ . ARG D 1 34 ? -17.185 60.020 -36.306 1.00 35.97 ? 15 ARG D CZ 1 ATOM 4913 N NH1 . ARG D 1 34 ? -17.459 61.204 -36.743 1.00 33.93 ? 15 ARG D NH1 1 ATOM 4914 N NH2 . ARG D 1 34 ? -17.694 59.629 -35.191 1.00 33.21 ? 15 ARG D NH2 1 ATOM 4915 N N . PRO D 1 35 ? -15.291 54.320 -38.976 1.00 29.13 ? 16 PRO D N 1 ATOM 4916 C CA . PRO D 1 35 ? -15.758 52.940 -38.872 1.00 25.17 ? 16 PRO D CA 1 ATOM 4917 C C . PRO D 1 35 ? -16.869 52.625 -37.909 1.00 24.73 ? 16 PRO D C 1 ATOM 4918 O O . PRO D 1 35 ? -17.408 51.567 -37.955 1.00 24.74 ? 16 PRO D O 1 ATOM 4919 C CB . PRO D 1 35 ? -14.548 52.222 -38.342 1.00 23.03 ? 16 PRO D CB 1 ATOM 4920 C CG . PRO D 1 35 ? -13.442 52.893 -38.959 1.00 24.06 ? 16 PRO D CG 1 ATOM 4921 C CD . PRO D 1 35 ? -13.775 54.292 -38.759 1.00 32.78 ? 16 PRO D CD 1 ATOM 4922 N N . ASP D 1 36 ? -17.107 53.475 -36.950 1.00 25.94 ? 17 ASP D N 1 ATOM 4923 C CA . ASP D 1 36 ? -18.081 53.236 -35.925 1.00 21.24 ? 17 ASP D CA 1 ATOM 4924 C C . ASP D 1 36 ? -19.412 53.813 -36.219 1.00 21.79 ? 17 ASP D C 1 ATOM 4925 O O . ASP D 1 36 ? -20.313 53.685 -35.461 1.00 29.12 ? 17 ASP D O 1 ATOM 4926 C CB . ASP D 1 36 ? -17.570 53.835 -34.644 1.00 26.68 ? 17 ASP D CB 1 ATOM 4927 C CG . ASP D 1 36 ? -17.137 55.274 -34.795 1.00 51.38 ? 17 ASP D CG 1 ATOM 4928 O OD1 . ASP D 1 36 ? -16.484 55.645 -35.789 1.00 36.33 ? 17 ASP D OD1 1 ATOM 4929 O OD2 . ASP D 1 36 ? -17.422 56.043 -33.855 1.00 50.72 ? 17 ASP D OD2 1 ATOM 4930 N N . VAL D 1 37 ? -19.531 54.467 -37.333 1.00 20.65 ? 18 VAL D N 1 ATOM 4931 C CA . VAL D 1 37 ? -20.762 55.159 -37.698 1.00 21.58 ? 18 VAL D CA 1 ATOM 4932 C C . VAL D 1 37 ? -21.444 54.519 -38.896 1.00 20.08 ? 18 VAL D C 1 ATOM 4933 O O . VAL D 1 37 ? -20.935 54.587 -40.021 1.00 22.37 ? 18 VAL D O 1 ATOM 4934 C CB . VAL D 1 37 ? -20.520 56.644 -38.083 1.00 24.92 ? 18 VAL D CB 1 ATOM 4935 C CG1 . VAL D 1 37 ? -21.837 57.287 -38.534 1.00 18.66 ? 18 VAL D CG1 1 ATOM 4936 C CG2 . VAL D 1 37 ? -19.878 57.418 -36.946 1.00 24.41 ? 18 VAL D CG2 1 ATOM 4937 N N . ILE D 1 38 ? -22.611 53.934 -38.654 1.00 18.55 ? 19 ILE D N 1 ATOM 4938 C CA . ILE D 1 38 ? -23.451 53.374 -39.714 1.00 23.35 ? 19 ILE D CA 1 ATOM 4939 C C . ILE D 1 38 ? -23.859 54.453 -40.760 1.00 26.97 ? 19 ILE D C 1 ATOM 4940 O O . ILE D 1 38 ? -24.323 55.552 -40.401 1.00 28.20 ? 19 ILE D O 1 ATOM 4941 C CB . ILE D 1 38 ? -24.669 52.636 -39.082 1.00 20.95 ? 19 ILE D CB 1 ATOM 4942 C CG1 . ILE D 1 38 ? -25.525 51.946 -40.133 1.00 22.52 ? 19 ILE D CG1 1 ATOM 4943 C CG2 . ILE D 1 38 ? -25.512 53.589 -38.230 1.00 28.81 ? 19 ILE D CG2 1 ATOM 4944 C CD1 . ILE D 1 38 ? -26.573 51.025 -39.499 1.00 26.36 ? 19 ILE D CD1 1 ATOM 4945 N N . PRO D 1 39 ? -23.645 54.152 -42.056 1.00 23.71 ? 20 PRO D N 1 ATOM 4946 C CA . PRO D 1 39 ? -23.860 55.141 -43.131 1.00 22.14 ? 20 PRO D CA 1 ATOM 4947 C C . PRO D 1 39 ? -25.318 55.208 -43.596 1.00 28.17 ? 20 PRO D C 1 ATOM 4948 O O . PRO D 1 39 ? -25.624 54.925 -44.752 1.00 33.26 ? 20 PRO D O 1 ATOM 4949 C CB . PRO D 1 39 ? -22.946 54.633 -44.264 1.00 26.05 ? 20 PRO D CB 1 ATOM 4950 C CG . PRO D 1 39 ? -22.907 53.113 -44.066 1.00 29.48 ? 20 PRO D CG 1 ATOM 4951 C CD . PRO D 1 39 ? -23.084 52.876 -42.557 1.00 26.80 ? 20 PRO D CD 1 ATOM 4952 N N . THR D 1 40 ? -26.218 55.565 -42.688 1.00 33.46 ? 21 THR D N 1 ATOM 4953 C CA . THR D 1 40 ? -27.626 55.720 -43.044 1.00 31.63 ? 21 THR D CA 1 ATOM 4954 C C . THR D 1 40 ? -27.787 56.972 -43.888 1.00 46.15 ? 21 THR D C 1 ATOM 4955 O O . THR D 1 40 ? -26.979 57.906 -43.793 1.00 45.88 ? 21 THR D O 1 ATOM 4956 C CB . THR D 1 40 ? -28.525 55.832 -41.807 1.00 28.97 ? 21 THR D CB 1 ATOM 4957 O OG1 . THR D 1 40 ? -28.049 56.890 -40.970 1.00 32.35 ? 21 THR D OG1 1 ATOM 4958 C CG2 . THR D 1 40 ? -28.525 54.518 -41.016 1.00 31.14 ? 21 THR D CG2 1 ATOM 4959 N N . GLN D 1 41 ? -28.767 56.956 -44.775 1.00 54.37 ? 22 GLN D N 1 ATOM 4960 C CA . GLN D 1 41 ? -29.022 58.085 -45.634 1.00 56.60 ? 22 GLN D CA 1 ATOM 4961 C C . GLN D 1 41 ? -30.437 58.542 -45.532 1.00 60.75 ? 22 GLN D C 1 ATOM 4962 O O . GLN D 1 41 ? -31.321 57.881 -46.001 1.00 67.52 ? 22 GLN D O 1 ATOM 4963 C CB . GLN D 1 41 ? -28.801 57.680 -47.066 1.00 58.22 ? 22 GLN D CB 1 ATOM 4964 C CG . GLN D 1 41 ? -27.524 58.173 -47.702 1.00 65.47 ? 22 GLN D CG 1 ATOM 4965 C CD . GLN D 1 41 ? -27.496 57.844 -49.174 1.00 78.60 ? 22 GLN D CD 1 ATOM 4966 O OE1 . GLN D 1 41 ? -27.814 56.737 -49.571 1.00 73.38 ? 22 GLN D OE1 1 ATOM 4967 N NE2 . GLN D 1 41 ? -27.134 58.814 -49.990 1.00 78.68 ? 22 GLN D NE2 1 ATOM 4968 N N . ARG D 1 42 ? -30.640 59.723 -44.993 1.00 68.98 ? 23 ARG D N 1 ATOM 4969 C CA . ARG D 1 42 ? -31.965 60.294 -44.867 1.00 78.67 ? 23 ARG D CA 1 ATOM 4970 C C . ARG D 1 42 ? -32.963 59.377 -44.150 1.00 70.53 ? 23 ARG D C 1 ATOM 4971 O O . ARG D 1 42 ? -34.124 59.275 -44.520 1.00 62.39 ? 23 ARG D O 1 ATOM 4972 C CB . ARG D 1 42 ? -32.477 60.815 -46.196 1.00 71.87 ? 23 ARG D CB 1 ATOM 4973 C CG . ARG D 1 42 ? -31.790 62.090 -46.646 1.00 80.99 ? 23 ARG D CG 1 ATOM 4974 C CD . ARG D 1 42 ? -32.633 62.972 -47.559 1.00 93.71 ? 23 ARG D CD 1 ATOM 4975 N NE . ARG D 1 42 ? -32.556 62.617 -48.975 1.00 105.85 ? 23 ARG D NE 1 ATOM 4976 C CZ . ARG D 1 42 ? -33.607 62.473 -49.783 1.00 110.55 ? 23 ARG D CZ 1 ATOM 4977 N NH1 . ARG D 1 42 ? -34.839 62.647 -49.334 1.00 101.79 ? 23 ARG D NH1 1 ATOM 4978 N NH2 . ARG D 1 42 ? -33.420 62.158 -51.059 1.00 110.33 ? 23 ARG D NH2 1 ATOM 4979 N N . ASP D 1 43 ? -32.505 58.752 -43.078 1.00 64.65 ? 24 ASP D N 1 ATOM 4980 C CA . ASP D 1 43 ? -33.373 57.960 -42.244 1.00 80.97 ? 24 ASP D CA 1 ATOM 4981 C C . ASP D 1 43 ? -33.792 56.606 -42.799 1.00 73.21 ? 24 ASP D C 1 ATOM 4982 O O . ASP D 1 43 ? -34.832 56.069 -42.456 1.00 73.16 ? 24 ASP D O 1 ATOM 4983 C CB . ASP D 1 43 ? -34.609 58.767 -41.915 1.00 81.39 ? 24 ASP D CB 1 ATOM 4984 C CG . ASP D 1 43 ? -35.143 58.456 -40.573 1.00 92.38 ? 24 ASP D CG 1 ATOM 4985 O OD1 . ASP D 1 43 ? -34.441 58.751 -39.594 1.00 88.80 ? 24 ASP D OD1 1 ATOM 4986 O OD2 . ASP D 1 43 ? -36.256 57.914 -40.504 1.00 100.67 ? 24 ASP D OD2 1 ATOM 4987 N N . ARG D 1 44 ? -32.969 56.051 -43.656 1.00 66.89 ? 25 ARG D N 1 ATOM 4988 C CA . ARG D 1 44 ? -33.302 54.818 -44.300 1.00 55.20 ? 25 ARG D CA 1 ATOM 4989 C C . ARG D 1 44 ? -32.342 53.751 -43.933 1.00 50.90 ? 25 ARG D C 1 ATOM 4990 O O . ARG D 1 44 ? -31.241 53.998 -43.514 1.00 48.34 ? 25 ARG D O 1 ATOM 4991 C CB . ARG D 1 44 ? -33.277 54.992 -45.788 1.00 53.88 ? 25 ARG D CB 1 ATOM 4992 C CG . ARG D 1 44 ? -33.883 56.286 -46.217 1.00 64.61 ? 25 ARG D CG 1 ATOM 4993 C CD . ARG D 1 44 ? -34.741 56.121 -47.441 1.00 73.46 ? 25 ARG D CD 1 ATOM 4994 N NE . ARG D 1 44 ? -35.390 57.388 -47.721 1.00 90.80 ? 25 ARG D NE 1 ATOM 4995 C CZ . ARG D 1 44 ? -35.052 58.212 -48.702 1.00 87.54 ? 25 ARG D CZ 1 ATOM 4996 N NH1 . ARG D 1 44 ? -34.085 57.898 -49.545 1.00 75.87 ? 25 ARG D NH1 1 ATOM 4997 N NH2 . ARG D 1 44 ? -35.711 59.345 -48.845 1.00 92.29 ? 25 ARG D NH2 1 ATOM 4998 N N . PRO D 1 45 ? -32.858 52.487 -44.095 1.00 36.82 ? 26 PRO D N 1 ATOM 4999 C CA . PRO D 1 45 ? -31.931 51.405 -43.814 1.00 37.32 ? 26 PRO D CA 1 ATOM 5000 C C . PRO D 1 45 ? -30.715 51.376 -44.704 1.00 35.90 ? 26 PRO D C 1 ATOM 5001 O O . PRO D 1 45 ? -30.803 51.772 -45.814 1.00 37.15 ? 26 PRO D O 1 ATOM 5002 C CB . PRO D 1 45 ? -32.744 50.191 -44.165 1.00 37.86 ? 26 PRO D CB 1 ATOM 5003 C CG . PRO D 1 45 ? -34.073 50.540 -43.765 1.00 40.29 ? 26 PRO D CG 1 ATOM 5004 C CD . PRO D 1 45 ? -34.218 51.857 -44.357 1.00 34.72 ? 26 PRO D CD 1 ATOM 5005 N N . VAL D 1 46 ? -29.583 50.918 -44.214 1.00 30.53 ? 27 VAL D N 1 ATOM 5006 C CA . VAL D 1 46 ? -28.520 50.566 -45.124 1.00 24.42 ? 27 VAL D CA 1 ATOM 5007 C C . VAL D 1 46 ? -28.930 49.248 -45.748 1.00 29.14 ? 27 VAL D C 1 ATOM 5008 O O . VAL D 1 46 ? -29.221 48.285 -45.036 1.00 28.78 ? 27 VAL D O 1 ATOM 5009 C CB . VAL D 1 46 ? -27.210 50.363 -44.375 1.00 22.77 ? 27 VAL D CB 1 ATOM 5010 C CG1 . VAL D 1 46 ? -26.104 49.948 -45.349 1.00 24.60 ? 27 VAL D CG1 1 ATOM 5011 C CG2 . VAL D 1 46 ? -26.840 51.634 -43.624 1.00 27.49 ? 27 VAL D CG2 1 ATOM 5012 N N . ALA D 1 47 ? -28.985 49.185 -47.071 1.00 28.54 ? 28 ALA D N 1 ATOM 5013 C CA . ALA D 1 47 ? -29.367 47.932 -47.692 1.00 24.16 ? 28 ALA D CA 1 ATOM 5014 C C . ALA D 1 47 ? -28.128 47.064 -47.866 1.00 28.89 ? 28 ALA D C 1 ATOM 5015 O O . ALA D 1 47 ? -27.245 47.366 -48.679 1.00 25.50 ? 28 ALA D O 1 ATOM 5016 C CB . ALA D 1 47 ? -30.051 48.170 -49.001 1.00 21.99 ? 28 ALA D CB 1 ATOM 5017 N N . VAL D 1 48 ? -28.067 45.979 -47.099 1.00 28.66 ? 29 VAL D N 1 ATOM 5018 C CA . VAL D 1 48 ? -26.968 45.024 -47.210 1.00 23.83 ? 29 VAL D CA 1 ATOM 5019 C C . VAL D 1 48 ? -27.418 43.811 -48.007 1.00 23.57 ? 29 VAL D C 1 ATOM 5020 O O . VAL D 1 48 ? -28.475 43.253 -47.734 1.00 31.70 ? 29 VAL D O 1 ATOM 5021 C CB . VAL D 1 48 ? -26.502 44.575 -45.806 1.00 23.61 ? 29 VAL D CB 1 ATOM 5022 C CG1 . VAL D 1 48 ? -25.307 43.633 -45.906 1.00 18.20 ? 29 VAL D CG1 1 ATOM 5023 C CG2 . VAL D 1 48 ? -26.194 45.788 -44.921 1.00 17.19 ? 29 VAL D CG2 1 ATOM 5024 N N . SER D 1 49 ? -26.626 43.395 -48.985 1.00 23.08 ? 30 SER D N 1 ATOM 5025 C CA . SER D 1 49 ? -26.919 42.147 -49.693 1.00 25.80 ? 30 SER D CA 1 ATOM 5026 C C . SER D 1 49 ? -25.999 41.079 -49.188 1.00 26.67 ? 30 SER D C 1 ATOM 5027 O O . SER D 1 49 ? -24.818 41.331 -48.978 1.00 27.48 ? 30 SER D O 1 ATOM 5028 C CB . SER D 1 49 ? -26.680 42.299 -51.185 1.00 25.53 ? 30 SER D CB 1 ATOM 5029 O OG . SER D 1 49 ? -27.202 43.532 -51.624 1.00 46.92 ? 30 SER D OG 1 ATOM 5030 N N . VAL D 1 50 ? -26.533 39.879 -49.012 1.00 30.90 ? 31 VAL D N 1 ATOM 5031 C CA . VAL D 1 50 ? -25.733 38.751 -48.547 1.00 30.09 ? 31 VAL D CA 1 ATOM 5032 C C . VAL D 1 50 ? -25.891 37.544 -49.462 1.00 27.31 ? 31 VAL D C 1 ATOM 5033 O O . VAL D 1 50 ? -26.989 37.175 -49.825 1.00 35.59 ? 31 VAL D O 1 ATOM 5034 C CB . VAL D 1 50 ? -26.138 38.332 -47.129 1.00 31.05 ? 31 VAL D CB 1 ATOM 5035 C CG1 . VAL D 1 50 ? -25.251 37.203 -46.652 1.00 28.86 ? 31 VAL D CG1 1 ATOM 5036 C CG2 . VAL D 1 50 ? -26.055 39.523 -46.176 1.00 34.74 ? 31 VAL D CG2 1 ATOM 5037 N N . SER D 1 51 ? -24.784 36.921 -49.821 1.00 28.35 ? 32 SER D N 1 ATOM 5038 C CA . SER D 1 51 ? -24.825 35.726 -50.642 1.00 29.59 ? 32 SER D CA 1 ATOM 5039 C C . SER D 1 51 ? -23.737 34.732 -50.183 1.00 28.57 ? 32 SER D C 1 ATOM 5040 O O . SER D 1 51 ? -22.567 35.106 -50.053 1.00 27.45 ? 32 SER D O 1 ATOM 5041 C CB . SER D 1 51 ? -24.640 36.111 -52.117 1.00 33.28 ? 32 SER D CB 1 ATOM 5042 O OG . SER D 1 51 ? -24.691 34.969 -52.958 1.00 36.32 ? 32 SER D OG 1 ATOM 5043 N N . LEU D 1 52 ? -24.112 33.476 -49.935 1.00 26.63 ? 33 LEU D N 1 ATOM 5044 C CA . LEU D 1 52 ? -23.122 32.450 -49.597 1.00 22.87 ? 33 LEU D CA 1 ATOM 5045 C C . LEU D 1 52 ? -22.758 31.589 -50.803 1.00 21.23 ? 33 LEU D C 1 ATOM 5046 O O . LEU D 1 52 ? -23.637 31.065 -51.472 1.00 32.37 ? 33 LEU D O 1 ATOM 5047 C CB . LEU D 1 52 ? -23.624 31.537 -48.475 1.00 23.60 ? 33 LEU D CB 1 ATOM 5048 C CG . LEU D 1 52 ? -24.159 32.250 -47.238 1.00 23.27 ? 33 LEU D CG 1 ATOM 5049 C CD1 . LEU D 1 52 ? -24.370 31.272 -46.082 1.00 23.03 ? 33 LEU D CD1 1 ATOM 5050 C CD2 . LEU D 1 52 ? -23.237 33.390 -46.824 1.00 24.36 ? 33 LEU D CD2 1 ATOM 5051 N N . LYS D 1 53 ? -21.467 31.440 -51.073 1.00 18.53 ? 34 LYS D N 1 ATOM 5052 C CA . LYS D 1 53 ? -21.005 30.520 -52.094 1.00 18.62 ? 34 LYS D CA 1 ATOM 5053 C C . LYS D 1 53 ? -20.330 29.365 -51.384 1.00 22.86 ? 34 LYS D C 1 ATOM 5054 O O . LYS D 1 53 ? -19.280 29.551 -50.752 1.00 21.71 ? 34 LYS D O 1 ATOM 5055 C CB . LYS D 1 53 ? -20.007 31.194 -53.025 1.00 19.94 ? 34 LYS D CB 1 ATOM 5056 C CG . LYS D 1 53 ? -20.370 32.608 -53.412 1.00 31.20 ? 34 LYS D CG 1 ATOM 5057 C CD . LYS D 1 53 ? -21.499 32.663 -54.427 1.00 34.90 ? 34 LYS D CD 1 ATOM 5058 C CE . LYS D 1 53 ? -21.832 34.113 -54.801 1.00 42.48 ? 34 LYS D CE 1 ATOM 5059 N NZ . LYS D 1 53 ? -22.977 34.189 -55.765 1.00 54.13 ? 34 LYS D NZ 1 ATOM 5060 N N . PHE D 1 54 ? -20.912 28.170 -51.481 1.00 24.08 ? 35 PHE D N 1 ATOM 5061 C CA . PHE D 1 54 ? -20.345 27.035 -50.763 1.00 22.08 ? 35 PHE D CA 1 ATOM 5062 C C . PHE D 1 54 ? -19.111 26.478 -51.440 1.00 22.90 ? 35 PHE D C 1 ATOM 5063 O O . PHE D 1 54 ? -19.081 26.296 -52.653 1.00 24.91 ? 35 PHE D O 1 ATOM 5064 C CB . PHE D 1 54 ? -21.392 25.961 -50.527 1.00 21.78 ? 35 PHE D CB 1 ATOM 5065 C CG . PHE D 1 54 ? -22.490 26.420 -49.654 1.00 21.89 ? 35 PHE D CG 1 ATOM 5066 C CD1 . PHE D 1 54 ? -22.343 26.406 -48.277 1.00 20.31 ? 35 PHE D CD1 1 ATOM 5067 C CD2 . PHE D 1 54 ? -23.654 26.929 -50.204 1.00 27.88 ? 35 PHE D CD2 1 ATOM 5068 C CE1 . PHE D 1 54 ? -23.367 26.863 -47.443 1.00 26.66 ? 35 PHE D CE1 1 ATOM 5069 C CE2 . PHE D 1 54 ? -24.681 27.396 -49.384 1.00 36.69 ? 35 PHE D CE2 1 ATOM 5070 C CZ . PHE D 1 54 ? -24.540 27.359 -47.997 1.00 31.16 ? 35 PHE D CZ 1 ATOM 5071 N N . ILE D 1 55 ? -18.083 26.237 -50.637 1.00 20.05 ? 36 ILE D N 1 ATOM 5072 C CA . ILE D 1 55 ? -16.823 25.745 -51.166 1.00 26.16 ? 36 ILE D CA 1 ATOM 5073 C C . ILE D 1 55 ? -16.553 24.301 -50.729 1.00 29.58 ? 36 ILE D C 1 ATOM 5074 O O . ILE D 1 55 ? -15.979 23.516 -51.492 1.00 31.69 ? 36 ILE D O 1 ATOM 5075 C CB . ILE D 1 55 ? -15.626 26.658 -50.760 1.00 27.34 ? 36 ILE D CB 1 ATOM 5076 C CG1 . ILE D 1 55 ? -15.959 28.143 -50.966 1.00 21.31 ? 36 ILE D CG1 1 ATOM 5077 C CG2 . ILE D 1 55 ? -14.366 26.261 -51.528 1.00 22.65 ? 36 ILE D CG2 1 ATOM 5078 C CD1 . ILE D 1 55 ? -16.353 28.500 -52.390 1.00 21.81 ? 36 ILE D CD1 1 ATOM 5079 N N . ASN D 1 56 ? -16.960 23.948 -49.508 1.00 22.92 ? 37 ASN D N 1 ATOM 5080 C CA . ASN D 1 56 ? -16.729 22.596 -49.009 1.00 19.36 ? 37 ASN D CA 1 ATOM 5081 C C . ASN D 1 56 ? -17.638 22.197 -47.859 1.00 23.90 ? 37 ASN D C 1 ATOM 5082 O O . ASN D 1 56 ? -18.146 23.044 -47.134 1.00 25.62 ? 37 ASN D O 1 ATOM 5083 C CB . ASN D 1 56 ? -15.279 22.456 -48.574 1.00 26.93 ? 37 ASN D CB 1 ATOM 5084 C CG . ASN D 1 56 ? -14.668 21.128 -48.986 1.00 24.77 ? 37 ASN D CG 1 ATOM 5085 O OD1 . ASN D 1 56 ? -15.292 20.076 -48.847 1.00 22.10 ? 37 ASN D OD1 1 ATOM 5086 N ND2 . ASN D 1 56 ? -13.436 21.177 -49.501 1.00 25.54 ? 37 ASN D ND2 1 ATOM 5087 N N . ILE D 1 57 ? -17.851 20.896 -47.695 1.00 24.33 ? 38 ILE D N 1 ATOM 5088 C CA . ILE D 1 57 ? -18.571 20.383 -46.532 1.00 19.60 ? 38 ILE D CA 1 ATOM 5089 C C . ILE D 1 57 ? -17.662 19.335 -45.924 1.00 23.61 ? 38 ILE D C 1 ATOM 5090 O O . ILE D 1 57 ? -17.188 18.450 -46.630 1.00 27.09 ? 38 ILE D O 1 ATOM 5091 C CB . ILE D 1 57 ? -19.939 19.809 -46.918 1.00 16.05 ? 38 ILE D CB 1 ATOM 5092 C CG1 . ILE D 1 57 ? -20.822 20.927 -47.448 1.00 16.65 ? 38 ILE D CG1 1 ATOM 5093 C CG2 . ILE D 1 57 ? -20.608 19.160 -45.733 1.00 14.86 ? 38 ILE D CG2 1 ATOM 5094 C CD1 . ILE D 1 57 ? -22.149 20.489 -47.935 1.00 19.26 ? 38 ILE D CD1 1 ATOM 5095 N N . LEU D 1 58 ? -17.373 19.454 -44.630 1.00 28.52 ? 39 LEU D N 1 ATOM 5096 C CA . LEU D 1 58 ? -16.172 18.812 -44.087 1.00 26.73 ? 39 LEU D CA 1 ATOM 5097 C C . LEU D 1 58 ? -16.424 17.731 -43.079 1.00 34.43 ? 39 LEU D C 1 ATOM 5098 O O . LEU D 1 58 ? -15.841 16.654 -43.170 1.00 40.28 ? 39 LEU D O 1 ATOM 5099 C CB . LEU D 1 58 ? -15.221 19.844 -43.480 1.00 26.53 ? 39 LEU D CB 1 ATOM 5100 C CG . LEU D 1 58 ? -14.480 20.738 -44.464 1.00 30.48 ? 39 LEU D CG 1 ATOM 5101 C CD1 . LEU D 1 58 ? -13.598 21.699 -43.709 1.00 25.44 ? 39 LEU D CD1 1 ATOM 5102 C CD2 . LEU D 1 58 ? -13.650 19.898 -45.438 1.00 33.75 ? 39 LEU D CD2 1 ATOM 5103 N N . GLU D 1 59 ? -17.253 18.020 -42.088 1.00 33.31 ? 40 GLU D N 1 ATOM 5104 C CA . GLU D 1 59 ? -17.422 17.063 -41.008 1.00 41.02 ? 40 GLU D CA 1 ATOM 5105 C C . GLU D 1 59 ? -18.859 16.997 -40.599 1.00 47.18 ? 40 GLU D C 1 ATOM 5106 O O . GLU D 1 59 ? -19.368 17.863 -39.886 1.00 54.44 ? 40 GLU D O 1 ATOM 5107 C CB . GLU D 1 59 ? -16.534 17.398 -39.810 1.00 49.83 ? 40 GLU D CB 1 ATOM 5108 C CG . GLU D 1 59 ? -15.408 16.398 -39.610 1.00 69.63 ? 40 GLU D CG 1 ATOM 5109 C CD . GLU D 1 59 ? -14.165 17.034 -39.009 1.00 82.43 ? 40 GLU D CD 1 ATOM 5110 O OE1 . GLU D 1 59 ? -14.186 18.265 -38.758 1.00 77.25 ? 40 GLU D OE1 1 ATOM 5111 O OE2 . GLU D 1 59 ? -13.172 16.301 -38.793 1.00 97.63 ? 40 GLU D OE2 1 ATOM 5112 N N . VAL D 1 60 ? -19.523 15.953 -41.057 1.00 45.49 ? 41 VAL D N 1 ATOM 5113 C CA . VAL D 1 60 ? -20.935 15.838 -40.789 1.00 36.30 ? 41 VAL D CA 1 ATOM 5114 C C . VAL D 1 60 ? -21.119 14.805 -39.698 1.00 31.50 ? 41 VAL D C 1 ATOM 5115 O O . VAL D 1 60 ? -20.399 13.806 -39.651 1.00 34.88 ? 41 VAL D O 1 ATOM 5116 C CB . VAL D 1 60 ? -21.692 15.476 -42.067 1.00 37.44 ? 41 VAL D CB 1 ATOM 5117 C CG1 . VAL D 1 60 ? -23.101 15.157 -41.760 1.00 34.85 ? 41 VAL D CG1 1 ATOM 5118 C CG2 . VAL D 1 60 ? -21.633 16.635 -43.047 1.00 34.73 ? 41 VAL D CG2 1 ATOM 5119 N N . ASN D 1 61 ? -22.044 15.084 -38.790 1.00 27.08 ? 42 ASN D N 1 ATOM 5120 C CA . ASN D 1 61 ? -22.387 14.160 -37.724 1.00 29.53 ? 42 ASN D CA 1 ATOM 5121 C C . ASN D 1 61 ? -23.910 14.116 -37.632 1.00 34.45 ? 42 ASN D C 1 ATOM 5122 O O . ASN D 1 61 ? -24.554 15.060 -37.163 1.00 35.70 ? 42 ASN D O 1 ATOM 5123 C CB . ASN D 1 61 ? -21.733 14.574 -36.394 1.00 28.84 ? 42 ASN D CB 1 ATOM 5124 C CG . ASN D 1 61 ? -21.897 13.533 -35.299 1.00 31.74 ? 42 ASN D CG 1 ATOM 5125 O OD1 . ASN D 1 61 ? -22.945 12.890 -35.173 1.00 32.42 ? 42 ASN D OD1 1 ATOM 5126 N ND2 . ASN D 1 61 ? -20.857 13.372 -34.485 1.00 40.32 ? 42 ASN D ND2 1 ATOM 5127 N N . GLU D 1 62 ? -24.483 13.011 -38.105 1.00 42.31 ? 43 GLU D N 1 ATOM 5128 C CA . GLU D 1 62 ? -25.938 12.825 -38.105 1.00 35.73 ? 43 GLU D CA 1 ATOM 5129 C C . GLU D 1 62 ? -26.455 12.570 -36.694 1.00 35.32 ? 43 GLU D C 1 ATOM 5130 O O . GLU D 1 62 ? -27.598 12.899 -36.388 1.00 31.16 ? 43 GLU D O 1 ATOM 5131 C CB . GLU D 1 62 ? -26.340 11.681 -39.044 1.00 37.93 ? 43 GLU D CB 1 ATOM 5132 C CG . GLU D 1 62 ? -27.798 11.735 -39.534 1.00 45.96 ? 43 GLU D CG 1 ATOM 5133 C CD . GLU D 1 62 ? -28.150 10.626 -40.547 1.00 61.23 ? 43 GLU D CD 1 ATOM 5134 O OE1 . GLU D 1 62 ? -27.222 9.943 -41.061 1.00 57.87 ? 43 GLU D OE1 1 ATOM 5135 O OE2 . GLU D 1 62 ? -29.365 10.451 -40.828 1.00 57.99 ? 43 GLU D OE2 1 ATOM 5136 N N . ILE D 1 63 ? -25.605 11.996 -35.837 1.00 35.93 ? 44 ILE D N 1 ATOM 5137 C CA . ILE D 1 63 ? -25.970 11.762 -34.443 1.00 36.06 ? 44 ILE D CA 1 ATOM 5138 C C . ILE D 1 63 ? -26.193 13.066 -33.675 1.00 39.10 ? 44 ILE D C 1 ATOM 5139 O O . ILE D 1 63 ? -27.201 13.208 -32.979 1.00 48.23 ? 44 ILE D O 1 ATOM 5140 C CB . ILE D 1 63 ? -24.911 10.947 -33.656 1.00 42.07 ? 44 ILE D CB 1 ATOM 5141 C CG1 . ILE D 1 63 ? -24.564 9.632 -34.363 1.00 41.89 ? 44 ILE D CG1 1 ATOM 5142 C CG2 . ILE D 1 63 ? -25.394 10.711 -32.214 1.00 38.79 ? 44 ILE D CG2 1 ATOM 5143 C CD1 . ILE D 1 63 ? -25.708 8.650 -34.449 1.00 44.30 ? 44 ILE D CD1 1 ATOM 5144 N N . THR D 1 64 ? -25.256 14.008 -33.793 1.00 35.83 ? 45 THR D N 1 ATOM 5145 C CA . THR D 1 64 ? -25.308 15.242 -33.004 1.00 34.61 ? 45 THR D CA 1 ATOM 5146 C C . THR D 1 64 ? -25.899 16.410 -33.769 1.00 33.85 ? 45 THR D C 1 ATOM 5147 O O . THR D 1 64 ? -26.031 17.501 -33.214 1.00 42.38 ? 45 THR D O 1 ATOM 5148 C CB . THR D 1 64 ? -23.928 15.682 -32.542 1.00 33.23 ? 45 THR D CB 1 ATOM 5149 O OG1 . THR D 1 64 ? -23.154 16.049 -33.687 1.00 31.88 ? 45 THR D OG1 1 ATOM 5150 C CG2 . THR D 1 64 ? -23.234 14.571 -31.785 1.00 31.81 ? 45 THR D CG2 1 ATOM 5151 N N . ASN D 1 65 ? -26.230 16.186 -35.036 1.00 30.11 ? 46 ASN D N 1 ATOM 5152 C CA . ASN D 1 65 ? -26.766 17.238 -35.890 1.00 32.41 ? 46 ASN D CA 1 ATOM 5153 C C . ASN D 1 65 ? -25.856 18.481 -36.045 1.00 34.93 ? 46 ASN D C 1 ATOM 5154 O O . ASN D 1 65 ? -26.277 19.615 -35.794 1.00 36.09 ? 46 ASN D O 1 ATOM 5155 C CB . ASN D 1 65 ? -28.172 17.635 -35.425 1.00 32.03 ? 46 ASN D CB 1 ATOM 5156 C CG . ASN D 1 65 ? -29.276 16.813 -36.093 1.00 37.06 ? 46 ASN D CG 1 ATOM 5157 O OD1 . ASN D 1 65 ? -29.087 16.199 -37.151 1.00 44.20 ? 46 ASN D OD1 1 ATOM 5158 N ND2 . ASN D 1 65 ? -30.447 16.828 -35.486 1.00 35.60 ? 46 ASN D ND2 1 ATOM 5159 N N . GLU D 1 66 ? -24.617 18.249 -36.471 1.00 31.49 ? 47 GLU D N 1 ATOM 5160 C CA . GLU D 1 66 ? -23.636 19.305 -36.627 1.00 30.23 ? 47 GLU D CA 1 ATOM 5161 C C . GLU D 1 66 ? -22.905 19.188 -37.952 1.00 26.04 ? 47 GLU D C 1 ATOM 5162 O O . GLU D 1 66 ? -22.507 18.107 -38.334 1.00 31.67 ? 47 GLU D O 1 ATOM 5163 C CB . GLU D 1 66 ? -22.634 19.245 -35.474 1.00 32.95 ? 47 GLU D CB 1 ATOM 5164 C CG . GLU D 1 66 ? -23.261 19.544 -34.124 1.00 43.68 ? 47 GLU D CG 1 ATOM 5165 C CD . GLU D 1 66 ? -22.267 19.491 -32.966 1.00 57.74 ? 47 GLU D CD 1 ATOM 5166 O OE1 . GLU D 1 66 ? -21.031 19.529 -33.228 1.00 52.76 ? 47 GLU D OE1 1 ATOM 5167 O OE2 . GLU D 1 66 ? -22.741 19.411 -31.798 1.00 52.75 ? 47 GLU D OE2 1 ATOM 5168 N N . VAL D 1 67 ? -22.712 20.303 -38.643 1.00 23.86 ? 48 VAL D N 1 ATOM 5169 C CA . VAL D 1 67 ? -21.919 20.290 -39.866 1.00 29.95 ? 48 VAL D CA 1 ATOM 5170 C C . VAL D 1 67 ? -20.773 21.309 -39.832 1.00 34.55 ? 48 VAL D C 1 ATOM 5171 O O . VAL D 1 67 ? -20.817 22.291 -39.083 1.00 34.06 ? 48 VAL D O 1 ATOM 5172 C CB . VAL D 1 67 ? -22.790 20.556 -41.104 1.00 28.95 ? 48 VAL D CB 1 ATOM 5173 C CG1 . VAL D 1 67 ? -23.901 19.545 -41.185 1.00 31.31 ? 48 VAL D CG1 1 ATOM 5174 C CG2 . VAL D 1 67 ? -23.371 21.956 -41.042 1.00 30.52 ? 48 VAL D CG2 1 ATOM 5175 N N . ASP D 1 68 ? -19.755 21.058 -40.654 1.00 33.84 ? 49 ASP D N 1 ATOM 5176 C CA . ASP D 1 68 ? -18.616 21.949 -40.812 1.00 28.11 ? 49 ASP D CA 1 ATOM 5177 C C . ASP D 1 68 ? -18.573 22.484 -42.229 1.00 28.40 ? 49 ASP D C 1 ATOM 5178 O O . ASP D 1 68 ? -18.307 21.736 -43.168 1.00 30.97 ? 49 ASP D O 1 ATOM 5179 C CB . ASP D 1 68 ? -17.333 21.185 -40.552 1.00 32.36 ? 49 ASP D CB 1 ATOM 5180 C CG . ASP D 1 68 ? -16.432 21.897 -39.578 1.00 47.27 ? 49 ASP D CG 1 ATOM 5181 O OD1 . ASP D 1 68 ? -16.967 22.685 -38.765 1.00 58.09 ? 49 ASP D OD1 1 ATOM 5182 O OD2 . ASP D 1 68 ? -15.198 21.679 -39.621 1.00 50.01 ? 49 ASP D OD2 1 ATOM 5183 N N . VAL D 1 69 ? -18.823 23.773 -42.402 1.00 23.59 ? 50 VAL D N 1 ATOM 5184 C CA . VAL D 1 69 ? -18.902 24.312 -43.746 1.00 20.56 ? 50 VAL D CA 1 ATOM 5185 C C . VAL D 1 69 ? -17.781 25.322 -44.047 1.00 24.26 ? 50 VAL D C 1 ATOM 5186 O O . VAL D 1 69 ? -17.325 26.041 -43.154 1.00 27.51 ? 50 VAL D O 1 ATOM 5187 C CB . VAL D 1 69 ? -20.282 24.908 -43.980 1.00 19.50 ? 50 VAL D CB 1 ATOM 5188 C CG1 . VAL D 1 69 ? -20.419 25.389 -45.405 1.00 30.08 ? 50 VAL D CG1 1 ATOM 5189 C CG2 . VAL D 1 69 ? -21.332 23.853 -43.686 1.00 20.49 ? 50 VAL D CG2 1 ATOM 5190 N N . VAL D 1 70 ? -17.307 25.328 -45.289 1.00 17.31 ? 51 VAL D N 1 ATOM 5191 C CA . VAL D 1 70 ? -16.475 26.408 -45.787 1.00 15.73 ? 51 VAL D CA 1 ATOM 5192 C C . VAL D 1 70 ? -17.240 27.106 -46.904 1.00 17.82 ? 51 VAL D C 1 ATOM 5193 O O . VAL D 1 70 ? -17.684 26.469 -47.860 1.00 21.16 ? 51 VAL D O 1 ATOM 5194 C CB . VAL D 1 70 ? -15.134 25.894 -46.331 1.00 22.91 ? 51 VAL D CB 1 ATOM 5195 C CG1 . VAL D 1 70 ? -14.403 26.997 -47.075 1.00 15.86 ? 51 VAL D CG1 1 ATOM 5196 C CG2 . VAL D 1 70 ? -14.279 25.339 -45.195 1.00 18.79 ? 51 VAL D CG2 1 ATOM 5197 N N . PHE D 1 71 ? -17.386 28.422 -46.788 1.00 21.22 ? 52 PHE D N 1 ATOM 5198 C CA . PHE D 1 71 ? -18.156 29.206 -47.751 1.00 19.50 ? 52 PHE D CA 1 ATOM 5199 C C . PHE D 1 71 ? -17.619 30.631 -47.889 1.00 18.89 ? 52 PHE D C 1 ATOM 5200 O O . PHE D 1 71 ? -16.994 31.152 -46.955 1.00 21.07 ? 52 PHE D O 1 ATOM 5201 C CB . PHE D 1 71 ? -19.616 29.249 -47.314 1.00 16.28 ? 52 PHE D CB 1 ATOM 5202 C CG . PHE D 1 71 ? -19.812 29.833 -45.956 1.00 16.18 ? 52 PHE D CG 1 ATOM 5203 C CD1 . PHE D 1 71 ? -19.667 29.045 -44.826 1.00 17.05 ? 52 PHE D CD1 1 ATOM 5204 C CD2 . PHE D 1 71 ? -20.139 31.177 -45.802 1.00 21.84 ? 52 PHE D CD2 1 ATOM 5205 C CE1 . PHE D 1 71 ? -19.826 29.581 -43.548 1.00 19.80 ? 52 PHE D CE1 1 ATOM 5206 C CE2 . PHE D 1 71 ? -20.311 31.739 -44.527 1.00 22.11 ? 52 PHE D CE2 1 ATOM 5207 C CZ . PHE D 1 71 ? -20.153 30.929 -43.393 1.00 22.27 ? 52 PHE D CZ 1 ATOM 5208 N N . TRP D 1 72 ? -17.861 31.255 -49.047 1.00 16.81 ? 53 TRP D N 1 ATOM 5209 C CA . TRP D 1 72 ? -17.594 32.685 -49.210 1.00 20.21 ? 53 TRP D CA 1 ATOM 5210 C C . TRP D 1 72 ? -18.826 33.416 -48.758 1.00 20.68 ? 53 TRP D C 1 ATOM 5211 O O . TRP D 1 72 ? -19.926 33.044 -49.137 1.00 21.17 ? 53 TRP D O 1 ATOM 5212 C CB . TRP D 1 72 ? -17.299 33.089 -50.670 1.00 19.46 ? 53 TRP D CB 1 ATOM 5213 C CG . TRP D 1 72 ? -16.061 32.469 -51.258 1.00 20.90 ? 53 TRP D CG 1 ATOM 5214 C CD1 . TRP D 1 72 ? -15.193 31.595 -50.640 1.00 23.44 ? 53 TRP D CD1 1 ATOM 5215 C CD2 . TRP D 1 72 ? -15.561 32.656 -52.580 1.00 19.12 ? 53 TRP D CD2 1 ATOM 5216 N NE1 . TRP D 1 72 ? -14.191 31.230 -51.504 1.00 20.23 ? 53 TRP D NE1 1 ATOM 5217 C CE2 . TRP D 1 72 ? -14.387 31.856 -52.708 1.00 18.28 ? 53 TRP D CE2 1 ATOM 5218 C CE3 . TRP D 1 72 ? -15.991 33.415 -53.681 1.00 17.55 ? 53 TRP D CE3 1 ATOM 5219 C CZ2 . TRP D 1 72 ? -13.630 31.791 -53.882 1.00 17.48 ? 53 TRP D CZ2 1 ATOM 5220 C CZ3 . TRP D 1 72 ? -15.240 33.358 -54.862 1.00 26.44 ? 53 TRP D CZ3 1 ATOM 5221 C CH2 . TRP D 1 72 ? -14.070 32.546 -54.953 1.00 26.87 ? 53 TRP D CH2 1 ATOM 5222 N N . GLN D 1 73 ? -18.648 34.456 -47.949 1.00 24.20 ? 54 GLN D N 1 ATOM 5223 C CA . GLN D 1 73 ? -19.774 35.248 -47.479 1.00 19.96 ? 54 GLN D CA 1 ATOM 5224 C C . GLN D 1 73 ? -19.752 36.594 -48.178 1.00 23.57 ? 54 GLN D C 1 ATOM 5225 O O . GLN D 1 73 ? -19.243 37.578 -47.644 1.00 24.61 ? 54 GLN D O 1 ATOM 5226 C CB . GLN D 1 73 ? -19.710 35.426 -45.970 1.00 18.80 ? 54 GLN D CB 1 ATOM 5227 C CG . GLN D 1 73 ? -20.879 36.187 -45.412 1.00 28.11 ? 54 GLN D CG 1 ATOM 5228 C CD . GLN D 1 73 ? -20.880 36.219 -43.890 1.00 38.96 ? 54 GLN D CD 1 ATOM 5229 O OE1 . GLN D 1 73 ? -20.848 35.164 -43.223 1.00 31.18 ? 54 GLN D OE1 1 ATOM 5230 N NE2 . GLN D 1 73 ? -20.908 37.440 -43.327 1.00 38.32 ? 54 GLN D NE2 1 ATOM 5231 N N . GLN D 1 74 ? -20.312 36.639 -49.382 1.00 23.71 ? 55 GLN D N 1 ATOM 5232 C CA . GLN D 1 74 ? -20.265 37.854 -50.177 1.00 23.49 ? 55 GLN D CA 1 ATOM 5233 C C . GLN D 1 74 ? -21.247 38.905 -49.645 1.00 23.11 ? 55 GLN D C 1 ATOM 5234 O O . GLN D 1 74 ? -22.460 38.701 -49.664 1.00 23.56 ? 55 GLN D O 1 ATOM 5235 C CB . GLN D 1 74 ? -20.534 37.539 -51.645 1.00 25.57 ? 55 GLN D CB 1 ATOM 5236 C CG . GLN D 1 74 ? -20.581 38.767 -52.519 1.00 31.53 ? 55 GLN D CG 1 ATOM 5237 C CD . GLN D 1 74 ? -20.826 38.442 -53.970 1.00 42.07 ? 55 GLN D CD 1 ATOM 5238 O OE1 . GLN D 1 74 ? -20.338 37.431 -54.478 1.00 62.54 ? 55 GLN D OE1 1 ATOM 5239 N NE2 . GLN D 1 74 ? -21.584 39.297 -54.653 1.00 45.61 ? 55 GLN D NE2 1 ATOM 5240 N N . THR D 1 75 ? -20.704 40.031 -49.174 1.00 24.20 ? 56 THR D N 1 ATOM 5241 C CA . THR D 1 75 ? -21.489 41.075 -48.509 1.00 20.50 ? 56 THR D CA 1 ATOM 5242 C C . THR D 1 75 ? -21.314 42.417 -49.221 1.00 19.99 ? 56 THR D C 1 ATOM 5243 O O . THR D 1 75 ? -20.188 42.836 -49.484 1.00 21.68 ? 56 THR D O 1 ATOM 5244 C CB . THR D 1 75 ? -21.064 41.233 -47.036 1.00 19.52 ? 56 THR D CB 1 ATOM 5245 O OG1 . THR D 1 75 ? -20.880 39.942 -46.427 1.00 24.01 ? 56 THR D OG1 1 ATOM 5246 C CG2 . THR D 1 75 ? -22.109 42.008 -46.269 1.00 18.15 ? 56 THR D CG2 1 ATOM 5247 N N . THR D 1 76 ? -22.417 43.101 -49.515 1.00 20.28 ? 57 THR D N 1 ATOM 5248 C CA . THR D 1 76 ? -22.370 44.305 -50.353 1.00 18.25 ? 57 THR D CA 1 ATOM 5249 C C . THR D 1 76 ? -23.303 45.385 -49.840 1.00 19.98 ? 57 THR D C 1 ATOM 5250 O O . THR D 1 76 ? -24.468 45.112 -49.518 1.00 22.89 ? 57 THR D O 1 ATOM 5251 C CB . THR D 1 76 ? -22.742 43.977 -51.820 1.00 27.24 ? 57 THR D CB 1 ATOM 5252 O OG1 . THR D 1 76 ? -21.724 43.135 -52.409 1.00 30.56 ? 57 THR D OG1 1 ATOM 5253 C CG2 . THR D 1 76 ? -22.887 45.267 -52.649 1.00 23.22 ? 57 THR D CG2 1 ATOM 5254 N N . TRP D 1 77 ? -22.789 46.609 -49.761 1.00 18.92 ? 58 TRP D N 1 ATOM 5255 C CA . TRP D 1 77 ? -23.585 47.742 -49.298 1.00 19.38 ? 58 TRP D CA 1 ATOM 5256 C C . TRP D 1 77 ? -23.027 49.054 -49.824 1.00 23.57 ? 58 TRP D C 1 ATOM 5257 O O . TRP D 1 77 ? -21.974 49.089 -50.459 1.00 20.84 ? 58 TRP D O 1 ATOM 5258 C CB . TRP D 1 77 ? -23.645 47.784 -47.768 1.00 18.88 ? 58 TRP D CB 1 ATOM 5259 C CG . TRP D 1 77 ? -22.339 48.140 -47.160 1.00 19.33 ? 58 TRP D CG 1 ATOM 5260 C CD1 . TRP D 1 77 ? -21.916 49.385 -46.790 1.00 20.31 ? 58 TRP D CD1 1 ATOM 5261 C CD2 . TRP D 1 77 ? -21.262 47.248 -46.872 1.00 20.35 ? 58 TRP D CD2 1 ATOM 5262 N NE1 . TRP D 1 77 ? -20.640 49.320 -46.273 1.00 20.13 ? 58 TRP D NE1 1 ATOM 5263 C CE2 . TRP D 1 77 ? -20.210 48.018 -46.313 1.00 18.87 ? 58 TRP D CE2 1 ATOM 5264 C CE3 . TRP D 1 77 ? -21.080 45.866 -47.025 1.00 18.69 ? 58 TRP D CE3 1 ATOM 5265 C CZ2 . TRP D 1 77 ? -18.992 47.465 -45.911 1.00 17.22 ? 58 TRP D CZ2 1 ATOM 5266 C CZ3 . TRP D 1 77 ? -19.867 45.307 -46.630 1.00 19.94 ? 58 TRP D CZ3 1 ATOM 5267 C CH2 . TRP D 1 77 ? -18.831 46.114 -46.076 1.00 19.82 ? 58 TRP D CH2 1 ATOM 5268 N N . SER D 1 78 ? -23.729 50.141 -49.531 1.00 28.94 ? 59 SER D N 1 ATOM 5269 C CA . SER D 1 78 ? -23.318 51.437 -50.031 1.00 24.34 ? 59 SER D CA 1 ATOM 5270 C C . SER D 1 78 ? -22.938 52.401 -48.909 1.00 22.43 ? 59 SER D C 1 ATOM 5271 O O . SER D 1 78 ? -23.672 52.524 -47.936 1.00 25.23 ? 59 SER D O 1 ATOM 5272 C CB . SER D 1 78 ? -24.420 52.022 -50.891 1.00 29.54 ? 59 SER D CB 1 ATOM 5273 O OG . SER D 1 78 ? -24.019 53.262 -51.427 1.00 46.28 ? 59 SER D OG 1 ATOM 5274 N N . ASP D 1 79 ? -21.789 53.076 -49.065 1.00 28.79 ? 60 ASP D N 1 ATOM 5275 C CA . ASP D 1 79 ? -21.301 54.099 -48.124 1.00 30.21 ? 60 ASP D CA 1 ATOM 5276 C C . ASP D 1 79 ? -20.783 55.358 -48.856 1.00 30.97 ? 60 ASP D C 1 ATOM 5277 O O . ASP D 1 79 ? -19.614 55.420 -49.236 1.00 28.80 ? 60 ASP D O 1 ATOM 5278 C CB . ASP D 1 79 ? -20.193 53.515 -47.237 1.00 26.71 ? 60 ASP D CB 1 ATOM 5279 C CG . ASP D 1 79 ? -19.904 54.370 -45.986 1.00 33.64 ? 60 ASP D CG 1 ATOM 5280 O OD1 . ASP D 1 79 ? -20.200 55.594 -45.984 1.00 27.74 ? 60 ASP D OD1 1 ATOM 5281 O OD2 . ASP D 1 79 ? -19.377 53.803 -44.992 1.00 31.09 ? 60 ASP D OD2 1 ATOM 5282 N N . ARG D 1 80 ? -21.653 56.355 -49.028 1.00 28.91 ? 61 ARG D N 1 ATOM 5283 C CA . ARG D 1 80 ? -21.320 57.563 -49.789 1.00 36.23 ? 61 ARG D CA 1 ATOM 5284 C C . ARG D 1 80 ? -20.158 58.362 -49.205 1.00 30.72 ? 61 ARG D C 1 ATOM 5285 O O . ARG D 1 80 ? -19.480 59.090 -49.928 1.00 33.57 ? 61 ARG D O 1 ATOM 5286 C CB . ARG D 1 80 ? -22.546 58.472 -49.954 1.00 46.81 ? 61 ARG D CB 1 ATOM 5287 C CG . ARG D 1 80 ? -23.808 57.754 -50.447 1.00 66.62 ? 61 ARG D CG 1 ATOM 5288 C CD . ARG D 1 80 ? -23.830 57.481 -51.967 1.00 71.05 ? 61 ARG D CD 1 ATOM 5289 N NE . ARG D 1 80 ? -25.151 56.999 -52.413 1.00 86.41 ? 61 ARG D NE 1 ATOM 5290 C CZ . ARG D 1 80 ? -25.381 55.860 -53.076 1.00 84.56 ? 61 ARG D CZ 1 ATOM 5291 N NH1 . ARG D 1 80 ? -24.377 55.054 -53.412 1.00 82.45 ? 61 ARG D NH1 1 ATOM 5292 N NH2 . ARG D 1 80 ? -26.624 55.525 -53.421 1.00 71.03 ? 61 ARG D NH2 1 ATOM 5293 N N . THR D 1 81 ? -19.936 58.228 -47.903 1.00 30.48 ? 62 THR D N 1 ATOM 5294 C CA . THR D 1 81 ? -18.776 58.822 -47.223 1.00 30.32 ? 62 THR D CA 1 ATOM 5295 C C . THR D 1 81 ? -17.436 58.455 -47.884 1.00 27.03 ? 62 THR D C 1 ATOM 5296 O O . THR D 1 81 ? -16.458 59.189 -47.778 1.00 27.35 ? 62 THR D O 1 ATOM 5297 C CB . THR D 1 81 ? -18.751 58.357 -45.745 1.00 38.95 ? 62 THR D CB 1 ATOM 5298 O OG1 . THR D 1 81 ? -19.993 58.712 -45.114 1.00 43.81 ? 62 THR D OG1 1 ATOM 5299 C CG2 . THR D 1 81 ? -17.552 58.930 -44.953 1.00 29.29 ? 62 THR D CG2 1 ATOM 5300 N N . LEU D 1 82 ? -17.390 57.315 -48.565 1.00 27.34 ? 63 LEU D N 1 ATOM 5301 C CA . LEU D 1 82 ? -16.144 56.857 -49.177 1.00 27.72 ? 63 LEU D CA 1 ATOM 5302 C C . LEU D 1 82 ? -15.965 57.323 -50.613 1.00 24.98 ? 63 LEU D C 1 ATOM 5303 O O . LEU D 1 82 ? -14.913 57.096 -51.198 1.00 31.26 ? 63 LEU D O 1 ATOM 5304 C CB . LEU D 1 82 ? -16.066 55.329 -49.153 1.00 27.95 ? 63 LEU D CB 1 ATOM 5305 C CG . LEU D 1 82 ? -16.270 54.689 -47.786 1.00 27.36 ? 63 LEU D CG 1 ATOM 5306 C CD1 . LEU D 1 82 ? -16.579 53.215 -47.948 1.00 19.16 ? 63 LEU D CD1 1 ATOM 5307 C CD2 . LEU D 1 82 ? -15.026 54.922 -46.921 1.00 23.19 ? 63 LEU D CD2 1 ATOM 5308 N N . ALA D 1 83 ? -16.983 57.961 -51.186 1.00 23.66 ? 64 ALA D N 1 ATOM 5309 C CA . ALA D 1 83 ? -16.965 58.268 -52.617 1.00 24.51 ? 64 ALA D CA 1 ATOM 5310 C C . ALA D 1 83 ? -15.924 59.336 -53.006 1.00 27.52 ? 64 ALA D C 1 ATOM 5311 O O . ALA D 1 83 ? -15.534 60.168 -52.191 1.00 29.82 ? 64 ALA D O 1 ATOM 5312 C CB . ALA D 1 83 ? -18.337 58.655 -53.090 1.00 25.36 ? 64 ALA D CB 1 ATOM 5313 N N . TRP D 1 84 ? -15.459 59.287 -54.254 1.00 33.40 ? 65 TRP D N 1 ATOM 5314 C CA . TRP D 1 84 ? -14.543 60.302 -54.791 1.00 26.64 ? 65 TRP D CA 1 ATOM 5315 C C . TRP D 1 84 ? -14.817 60.544 -56.280 1.00 30.81 ? 65 TRP D C 1 ATOM 5316 O O . TRP D 1 84 ? -15.518 59.753 -56.917 1.00 39.10 ? 65 TRP D O 1 ATOM 5317 C CB . TRP D 1 84 ? -13.081 59.894 -54.566 1.00 25.62 ? 65 TRP D CB 1 ATOM 5318 C CG . TRP D 1 84 ? -12.616 58.688 -55.363 1.00 31.95 ? 65 TRP D CG 1 ATOM 5319 C CD1 . TRP D 1 84 ? -12.026 58.701 -56.597 1.00 32.58 ? 65 TRP D CD1 1 ATOM 5320 C CD2 . TRP D 1 84 ? -12.688 57.302 -54.969 1.00 29.32 ? 65 TRP D CD2 1 ATOM 5321 N NE1 . TRP D 1 84 ? -11.733 57.417 -56.996 1.00 29.26 ? 65 TRP D NE1 1 ATOM 5322 C CE2 . TRP D 1 84 ? -12.122 56.539 -56.013 1.00 27.91 ? 65 TRP D CE2 1 ATOM 5323 C CE3 . TRP D 1 84 ? -13.177 56.635 -53.835 1.00 19.94 ? 65 TRP D CE3 1 ATOM 5324 C CZ2 . TRP D 1 84 ? -12.027 55.146 -55.962 1.00 29.84 ? 65 TRP D CZ2 1 ATOM 5325 C CZ3 . TRP D 1 84 ? -13.087 55.258 -53.779 1.00 24.91 ? 65 TRP D CZ3 1 ATOM 5326 C CH2 . TRP D 1 84 ? -12.516 54.522 -54.837 1.00 31.14 ? 65 TRP D CH2 1 ATOM 5327 N N . ASN D 1 85 ? -14.277 61.619 -56.827 1.00 38.92 ? 66 ASN D N 1 ATOM 5328 C CA . ASN D 1 85 ? -14.390 61.904 -58.243 1.00 40.02 ? 66 ASN D CA 1 ATOM 5329 C C . ASN D 1 85 ? -13.388 61.061 -58.942 1.00 42.56 ? 66 ASN D C 1 ATOM 5330 O O . ASN D 1 85 ? -12.251 61.105 -58.616 1.00 50.00 ? 66 ASN D O 1 ATOM 5331 C CB . ASN D 1 85 ? -14.085 63.365 -58.512 1.00 40.27 ? 66 ASN D CB 1 ATOM 5332 C CG . ASN D 1 85 ? -14.541 63.812 -59.871 1.00 50.15 ? 66 ASN D CG 1 ATOM 5333 O OD1 . ASN D 1 85 ? -14.712 63.008 -60.750 1.00 52.33 ? 66 ASN D OD1 1 ATOM 5334 N ND2 . ASN D 1 85 ? -14.725 65.096 -60.047 1.00 57.29 ? 66 ASN D ND2 1 ATOM 5335 N N . SER D 1 86 ? -13.809 60.290 -59.918 1.00 43.82 ? 67 SER D N 1 ATOM 5336 C CA . SER D 1 86 ? -12.934 59.340 -60.545 1.00 44.34 ? 67 SER D CA 1 ATOM 5337 C C . SER D 1 86 ? -12.710 59.767 -61.952 1.00 51.60 ? 67 SER D C 1 ATOM 5338 O O . SER D 1 86 ? -12.599 58.964 -62.833 1.00 55.25 ? 67 SER D O 1 ATOM 5339 C CB . SER D 1 86 ? -13.529 57.953 -60.498 1.00 46.63 ? 67 SER D CB 1 ATOM 5340 O OG . SER D 1 86 ? -14.451 57.746 -61.533 1.00 52.78 ? 67 SER D OG 1 ATOM 5341 N N . SER D 1 87 ? -12.724 61.059 -62.165 1.00 50.88 ? 68 SER D N 1 ATOM 5342 C CA . SER D 1 87 ? -12.628 61.608 -63.478 1.00 55.82 ? 68 SER D CA 1 ATOM 5343 C C . SER D 1 87 ? -11.348 61.292 -64.213 1.00 65.71 ? 68 SER D C 1 ATOM 5344 O O . SER D 1 87 ? -11.410 60.907 -65.351 1.00 76.52 ? 68 SER D O 1 ATOM 5345 C CB . SER D 1 87 ? -12.773 63.111 -63.368 1.00 66.27 ? 68 SER D CB 1 ATOM 5346 O OG . SER D 1 87 ? -13.055 63.702 -64.613 1.00 80.66 ? 68 SER D OG 1 ATOM 5347 N N . HIS D 1 88 ? -10.190 61.419 -63.596 1.00 64.83 ? 69 HIS D N 1 ATOM 5348 C CA . HIS D 1 88 ? -8.968 60.921 -64.211 1.00 60.35 ? 69 HIS D CA 1 ATOM 5349 C C . HIS D 1 88 ? -8.206 60.228 -63.128 1.00 57.96 ? 69 HIS D C 1 ATOM 5350 O O . HIS D 1 88 ? -7.159 60.654 -62.717 1.00 59.25 ? 69 HIS D O 1 ATOM 5351 C CB . HIS D 1 88 ? -8.138 62.056 -64.796 1.00 67.60 ? 69 HIS D CB 1 ATOM 5352 C CG . HIS D 1 88 ? -8.814 62.810 -65.900 1.00 91.48 ? 69 HIS D CG 1 ATOM 5353 N ND1 . HIS D 1 88 ? -8.790 62.392 -67.211 1.00 97.15 ? 69 HIS D ND1 1 ATOM 5354 C CD2 . HIS D 1 88 ? -9.507 63.971 -65.892 1.00 95.72 ? 69 HIS D CD2 1 ATOM 5355 C CE1 . HIS D 1 88 ? -9.454 63.253 -67.959 1.00 95.52 ? 69 HIS D CE1 1 ATOM 5356 N NE2 . HIS D 1 88 ? -9.900 64.221 -67.183 1.00 91.71 ? 69 HIS D NE2 1 ATOM 5357 N N . SER D 1 89 ? -8.760 59.146 -62.642 1.00 49.78 ? 70 SER D N 1 ATOM 5358 C CA . SER D 1 89 ? -8.298 58.559 -61.443 1.00 39.98 ? 70 SER D CA 1 ATOM 5359 C C . SER D 1 89 ? -8.717 57.151 -61.435 1.00 42.42 ? 70 SER D C 1 ATOM 5360 O O . SER D 1 89 ? -9.484 56.750 -62.243 1.00 41.54 ? 70 SER D O 1 ATOM 5361 C CB . SER D 1 89 ? -8.963 59.252 -60.303 1.00 49.41 ? 70 SER D CB 1 ATOM 5362 O OG . SER D 1 89 ? -9.045 60.608 -60.593 1.00 59.68 ? 70 SER D OG 1 ATOM 5363 N N . PRO D 1 90 ? -8.147 56.384 -60.442 1.00 43.72 ? 71 PRO D N 1 ATOM 5364 C CA . PRO D 1 90 ? -8.690 55.038 -60.312 1.00 36.79 ? 71 PRO D CA 1 ATOM 5365 C C . PRO D 1 90 ? -10.141 55.035 -59.910 1.00 35.10 ? 71 PRO D C 1 ATOM 5366 O O . PRO D 1 90 ? -10.576 55.952 -59.287 1.00 38.31 ? 71 PRO D O 1 ATOM 5367 C CB . PRO D 1 90 ? -7.882 54.461 -59.172 1.00 39.66 ? 71 PRO D CB 1 ATOM 5368 C CG . PRO D 1 90 ? -6.603 55.124 -59.252 1.00 42.92 ? 71 PRO D CG 1 ATOM 5369 C CD . PRO D 1 90 ? -7.003 56.511 -59.433 1.00 37.12 ? 71 PRO D CD 1 ATOM 5370 N N . ASP D 1 91 ? -10.885 54.017 -60.298 1.00 35.33 ? 72 ASP D N 1 ATOM 5371 C CA . ASP D 1 91 ? -12.295 53.894 -59.927 1.00 39.81 ? 72 ASP D CA 1 ATOM 5372 C C . ASP D 1 91 ? -12.525 52.848 -58.805 1.00 40.34 ? 72 ASP D C 1 ATOM 5373 O O . ASP D 1 91 ? -13.668 52.585 -58.404 1.00 36.96 ? 72 ASP D O 1 ATOM 5374 C CB . ASP D 1 91 ? -13.122 53.553 -61.170 1.00 41.47 ? 72 ASP D CB 1 ATOM 5375 C CG . ASP D 1 91 ? -12.465 52.474 -62.019 1.00 54.21 ? 72 ASP D CG 1 ATOM 5376 O OD1 . ASP D 1 91 ? -11.313 52.096 -61.693 1.00 59.13 ? 72 ASP D OD1 1 ATOM 5377 O OD2 . ASP D 1 91 ? -13.082 52.013 -63.012 1.00 66.28 ? 72 ASP D OD2 1 ATOM 5378 N N . GLN D 1 92 ? -11.436 52.268 -58.299 1.00 32.53 ? 73 GLN D N 1 ATOM 5379 C CA . GLN D 1 92 ? -11.505 51.262 -57.242 1.00 27.22 ? 73 GLN D CA 1 ATOM 5380 C C . GLN D 1 92 ? -10.195 51.150 -56.436 1.00 26.76 ? 73 GLN D C 1 ATOM 5381 O O . GLN D 1 92 ? -9.093 51.364 -56.957 1.00 30.68 ? 73 GLN D O 1 ATOM 5382 C CB . GLN D 1 92 ? -11.823 49.907 -57.850 1.00 26.11 ? 73 GLN D CB 1 ATOM 5383 C CG . GLN D 1 92 ? -10.781 49.522 -58.864 1.00 42.31 ? 73 GLN D CG 1 ATOM 5384 C CD . GLN D 1 92 ? -10.874 48.086 -59.288 1.00 54.57 ? 73 GLN D CD 1 ATOM 5385 O OE1 . GLN D 1 92 ? -11.967 47.552 -59.494 1.00 61.18 ? 73 GLN D OE1 1 ATOM 5386 N NE2 . GLN D 1 92 ? -9.720 47.440 -59.421 1.00 54.44 ? 73 GLN D NE2 1 ATOM 5387 N N . VAL D 1 93 ? -10.324 50.799 -55.162 1.00 20.70 ? 74 VAL D N 1 ATOM 5388 C CA . VAL D 1 93 ? -9.177 50.524 -54.306 1.00 21.04 ? 74 VAL D CA 1 ATOM 5389 C C . VAL D 1 93 ? -9.526 49.365 -53.342 1.00 20.32 ? 74 VAL D C 1 ATOM 5390 O O . VAL D 1 93 ? -10.703 49.056 -53.140 1.00 18.46 ? 74 VAL D O 1 ATOM 5391 C CB . VAL D 1 93 ? -8.746 51.773 -53.485 1.00 19.22 ? 74 VAL D CB 1 ATOM 5392 C CG1 . VAL D 1 93 ? -8.168 52.861 -54.368 1.00 20.68 ? 74 VAL D CG1 1 ATOM 5393 C CG2 . VAL D 1 93 ? -9.914 52.308 -52.697 1.00 23.51 ? 74 VAL D CG2 1 ATOM 5394 N N . SER D 1 94 ? -8.512 48.720 -52.765 1.00 16.16 ? 75 SER D N 1 ATOM 5395 C CA . SER D 1 94 ? -8.741 47.738 -51.711 1.00 15.60 ? 75 SER D CA 1 ATOM 5396 C C . SER D 1 94 ? -8.408 48.360 -50.356 1.00 20.48 ? 75 SER D C 1 ATOM 5397 O O . SER D 1 94 ? -7.361 48.993 -50.184 1.00 22.98 ? 75 SER D O 1 ATOM 5398 C CB . SER D 1 94 ? -7.899 46.483 -51.932 1.00 23.11 ? 75 SER D CB 1 ATOM 5399 O OG . SER D 1 94 ? -8.485 45.639 -52.906 1.00 28.63 ? 75 SER D OG 1 ATOM 5400 N N . VAL D 1 95 ? -9.299 48.182 -49.390 1.00 21.10 ? 76 VAL D N 1 ATOM 5401 C CA . VAL D 1 95 ? -9.169 48.879 -48.108 1.00 20.75 ? 76 VAL D CA 1 ATOM 5402 C C . VAL D 1 95 ? -9.242 47.881 -46.966 1.00 19.93 ? 76 VAL D C 1 ATOM 5403 O O . VAL D 1 95 ? -10.127 47.025 -46.945 1.00 20.93 ? 76 VAL D O 1 ATOM 5404 C CB . VAL D 1 95 ? -10.312 49.891 -47.936 1.00 17.98 ? 76 VAL D CB 1 ATOM 5405 C CG1 . VAL D 1 95 ? -10.245 50.550 -46.566 1.00 16.60 ? 76 VAL D CG1 1 ATOM 5406 C CG2 . VAL D 1 95 ? -10.330 50.905 -49.091 1.00 12.85 ? 76 VAL D CG2 1 ATOM 5407 N N . PRO D 1 96 ? -8.311 47.977 -46.006 1.00 21.98 ? 77 PRO D N 1 ATOM 5408 C CA . PRO D 1 96 ? -8.411 47.100 -44.825 1.00 21.99 ? 77 PRO D CA 1 ATOM 5409 C C . PRO D 1 96 ? -9.737 47.355 -44.097 1.00 19.04 ? 77 PRO D C 1 ATOM 5410 O O . PRO D 1 96 ? -10.062 48.529 -43.888 1.00 21.96 ? 77 PRO D O 1 ATOM 5411 C CB . PRO D 1 96 ? -7.226 47.549 -43.951 1.00 15.46 ? 77 PRO D CB 1 ATOM 5412 C CG . PRO D 1 96 ? -6.279 48.204 -44.902 1.00 17.47 ? 77 PRO D CG 1 ATOM 5413 C CD . PRO D 1 96 ? -7.148 48.878 -45.941 1.00 21.86 ? 77 PRO D CD 1 ATOM 5414 N N . ILE D 1 97 ? -10.478 46.306 -43.735 1.00 13.43 ? 78 ILE D N 1 ATOM 5415 C CA . ILE D 1 97 ? -11.795 46.493 -43.118 1.00 16.66 ? 78 ILE D CA 1 ATOM 5416 C C . ILE D 1 97 ? -11.748 47.268 -41.794 1.00 20.18 ? 78 ILE D C 1 ATOM 5417 O O . ILE D 1 97 ? -12.754 47.832 -41.337 1.00 20.15 ? 78 ILE D O 1 ATOM 5418 C CB . ILE D 1 97 ? -12.578 45.178 -42.906 1.00 16.10 ? 78 ILE D CB 1 ATOM 5419 C CG1 . ILE D 1 97 ? -11.845 44.249 -41.958 1.00 13.18 ? 78 ILE D CG1 1 ATOM 5420 C CG2 . ILE D 1 97 ? -12.880 44.496 -44.251 1.00 20.77 ? 78 ILE D CG2 1 ATOM 5421 C CD1 . ILE D 1 97 ? -12.656 43.072 -41.552 1.00 9.71 ? 78 ILE D CD1 1 ATOM 5422 N N . SER D 1 98 ? -10.577 47.307 -41.178 1.00 17.70 ? 79 SER D N 1 ATOM 5423 C CA . SER D 1 98 ? -10.431 48.063 -39.949 1.00 20.40 ? 79 SER D CA 1 ATOM 5424 C C . SER D 1 98 ? -10.660 49.578 -40.171 1.00 23.82 ? 79 SER D C 1 ATOM 5425 O O . SER D 1 98 ? -10.926 50.318 -39.229 1.00 25.47 ? 79 SER D O 1 ATOM 5426 C CB . SER D 1 98 ? -9.069 47.769 -39.300 1.00 21.46 ? 79 SER D CB 1 ATOM 5427 O OG . SER D 1 98 ? -7.995 48.234 -40.108 1.00 28.86 ? 79 SER D OG 1 ATOM 5428 N N . SER D 1 99 ? -10.584 50.034 -41.415 1.00 24.57 ? 80 SER D N 1 ATOM 5429 C CA . SER D 1 99 ? -10.799 51.450 -41.721 1.00 22.29 ? 80 SER D CA 1 ATOM 5430 C C . SER D 1 99 ? -12.172 51.755 -42.313 1.00 24.76 ? 80 SER D C 1 ATOM 5431 O O . SER D 1 99 ? -12.357 52.831 -42.868 1.00 26.85 ? 80 SER D O 1 ATOM 5432 C CB . SER D 1 99 ? -9.752 51.955 -42.721 1.00 24.41 ? 80 SER D CB 1 ATOM 5433 O OG . SER D 1 99 ? -8.446 51.578 -42.341 1.00 38.37 ? 80 SER D OG 1 ATOM 5434 N N . LEU D 1 100 ? -13.117 50.820 -42.225 1.00 21.32 ? 81 LEU D N 1 ATOM 5435 C CA . LEU D 1 100 ? -14.451 51.005 -42.797 1.00 17.33 ? 81 LEU D CA 1 ATOM 5436 C C . LEU D 1 100 ? -15.523 50.611 -41.813 1.00 20.05 ? 81 LEU D C 1 ATOM 5437 O O . LEU D 1 100 ? -15.310 49.728 -40.964 1.00 20.34 ? 81 LEU D O 1 ATOM 5438 C CB . LEU D 1 100 ? -14.636 50.072 -43.972 1.00 21.46 ? 81 LEU D CB 1 ATOM 5439 C CG . LEU D 1 100 ? -13.776 50.282 -45.191 1.00 23.85 ? 81 LEU D CG 1 ATOM 5440 C CD1 . LEU D 1 100 ? -14.166 49.237 -46.216 1.00 17.35 ? 81 LEU D CD1 1 ATOM 5441 C CD2 . LEU D 1 100 ? -14.061 51.671 -45.688 1.00 25.77 ? 81 LEU D CD2 1 ATOM 5442 N N . TRP D 1 101 ? -16.698 51.216 -41.942 1.00 16.84 ? 82 TRP D N 1 ATOM 5443 C CA . TRP D 1 101 ? -17.849 50.633 -41.280 1.00 16.42 ? 82 TRP D CA 1 ATOM 5444 C C . TRP D 1 101 ? -18.188 49.325 -41.994 1.00 17.77 ? 82 TRP D C 1 ATOM 5445 O O . TRP D 1 101 ? -18.093 49.237 -43.203 1.00 19.16 ? 82 TRP D O 1 ATOM 5446 C CB . TRP D 1 101 ? -19.045 51.556 -41.299 1.00 14.16 ? 82 TRP D CB 1 ATOM 5447 C CG . TRP D 1 101 ? -20.236 50.927 -40.675 1.00 15.73 ? 82 TRP D CG 1 ATOM 5448 C CD1 . TRP D 1 101 ? -20.585 50.949 -39.359 1.00 15.31 ? 82 TRP D CD1 1 ATOM 5449 C CD2 . TRP D 1 101 ? -21.246 50.171 -41.350 1.00 18.72 ? 82 TRP D CD2 1 ATOM 5450 N NE1 . TRP D 1 101 ? -21.756 50.264 -39.175 1.00 17.09 ? 82 TRP D NE1 1 ATOM 5451 C CE2 . TRP D 1 101 ? -22.178 49.772 -40.376 1.00 17.83 ? 82 TRP D CE2 1 ATOM 5452 C CE3 . TRP D 1 101 ? -21.447 49.797 -42.681 1.00 21.38 ? 82 TRP D CE3 1 ATOM 5453 C CZ2 . TRP D 1 101 ? -23.306 49.005 -40.700 1.00 20.90 ? 82 TRP D CZ2 1 ATOM 5454 C CZ3 . TRP D 1 101 ? -22.566 49.037 -42.999 1.00 20.49 ? 82 TRP D CZ3 1 ATOM 5455 C CH2 . TRP D 1 101 ? -23.481 48.647 -42.010 1.00 21.66 ? 82 TRP D CH2 1 ATOM 5456 N N . VAL D 1 102 ? -18.590 48.319 -41.227 1.00 21.59 ? 83 VAL D N 1 ATOM 5457 C CA . VAL D 1 102 ? -18.931 46.991 -41.731 1.00 17.35 ? 83 VAL D CA 1 ATOM 5458 C C . VAL D 1 102 ? -20.190 46.537 -40.983 1.00 18.36 ? 83 VAL D C 1 ATOM 5459 O O . VAL D 1 102 ? -20.335 46.786 -39.784 1.00 19.89 ? 83 VAL D O 1 ATOM 5460 C CB . VAL D 1 102 ? -17.770 46.006 -41.478 1.00 13.45 ? 83 VAL D CB 1 ATOM 5461 C CG1 . VAL D 1 102 ? -18.278 44.587 -41.378 1.00 18.92 ? 83 VAL D CG1 1 ATOM 5462 C CG2 . VAL D 1 102 ? -16.720 46.131 -42.557 1.00 13.15 ? 83 VAL D CG2 1 ATOM 5463 N N . PRO D 1 103 ? -21.127 45.897 -41.689 1.00 19.41 ? 84 PRO D N 1 ATOM 5464 C CA . PRO D 1 103 ? -22.343 45.417 -41.005 1.00 18.65 ? 84 PRO D CA 1 ATOM 5465 C C . PRO D 1 103 ? -22.052 44.297 -39.997 1.00 20.16 ? 84 PRO D C 1 ATOM 5466 O O . PRO D 1 103 ? -21.216 43.412 -40.273 1.00 19.49 ? 84 PRO D O 1 ATOM 5467 C CB . PRO D 1 103 ? -23.217 44.901 -42.158 1.00 19.95 ? 84 PRO D CB 1 ATOM 5468 C CG . PRO D 1 103 ? -22.255 44.615 -43.283 1.00 18.47 ? 84 PRO D CG 1 ATOM 5469 C CD . PRO D 1 103 ? -21.126 45.611 -43.137 1.00 16.78 ? 84 PRO D CD 1 ATOM 5470 N N . ASP D 1 104 ? -22.743 44.338 -38.853 1.00 25.02 ? 85 ASP D N 1 ATOM 5471 C CA . ASP D 1 104 ? -22.530 43.375 -37.755 1.00 24.44 ? 85 ASP D CA 1 ATOM 5472 C C . ASP D 1 104 ? -23.317 42.070 -37.925 1.00 24.07 ? 85 ASP D C 1 ATOM 5473 O O . ASP D 1 104 ? -24.102 41.698 -37.056 1.00 26.78 ? 85 ASP D O 1 ATOM 5474 C CB . ASP D 1 104 ? -22.839 44.009 -36.384 1.00 22.60 ? 85 ASP D CB 1 ATOM 5475 C CG . ASP D 1 104 ? -24.288 44.507 -36.256 1.00 26.94 ? 85 ASP D CG 1 ATOM 5476 O OD1 . ASP D 1 104 ? -24.873 44.909 -37.287 1.00 25.67 ? 85 ASP D OD1 1 ATOM 5477 O OD2 . ASP D 1 104 ? -24.840 44.498 -35.116 1.00 27.99 ? 85 ASP D OD2 1 ATOM 5478 N N . LEU D 1 105 ? -23.096 41.369 -39.038 1.00 24.17 ? 86 LEU D N 1 ATOM 5479 C CA . LEU D 1 105 ? -23.804 40.118 -39.307 1.00 20.90 ? 86 LEU D CA 1 ATOM 5480 C C . LEU D 1 105 ? -23.300 38.959 -38.429 1.00 21.72 ? 86 LEU D C 1 ATOM 5481 O O . LEU D 1 105 ? -22.130 38.915 -38.037 1.00 21.87 ? 86 LEU D O 1 ATOM 5482 C CB . LEU D 1 105 ? -23.693 39.759 -40.789 1.00 21.97 ? 86 LEU D CB 1 ATOM 5483 C CG . LEU D 1 105 ? -24.172 40.853 -41.744 1.00 23.79 ? 86 LEU D CG 1 ATOM 5484 C CD1 . LEU D 1 105 ? -23.904 40.470 -43.208 1.00 21.02 ? 86 LEU D CD1 1 ATOM 5485 C CD2 . LEU D 1 105 ? -25.655 41.181 -41.527 1.00 28.43 ? 86 LEU D CD2 1 ATOM 5486 N N . ALA D 1 106 ? -24.203 38.039 -38.109 1.00 18.28 ? 87 ALA D N 1 ATOM 5487 C CA . ALA D 1 106 ? -23.863 36.870 -37.323 1.00 18.26 ? 87 ALA D CA 1 ATOM 5488 C C . ALA D 1 106 ? -24.742 35.724 -37.766 1.00 21.41 ? 87 ALA D C 1 ATOM 5489 O O . ALA D 1 106 ? -25.865 35.937 -38.225 1.00 22.33 ? 87 ALA D O 1 ATOM 5490 C CB . ALA D 1 106 ? -24.079 37.141 -35.853 1.00 21.38 ? 87 ALA D CB 1 ATOM 5491 N N . ALA D 1 107 ? -24.230 34.507 -37.621 1.00 20.71 ? 88 ALA D N 1 ATOM 5492 C CA . ALA D 1 107 ? -25.007 33.303 -37.912 1.00 20.40 ? 88 ALA D CA 1 ATOM 5493 C C . ALA D 1 107 ? -25.650 32.824 -36.621 1.00 22.46 ? 88 ALA D C 1 ATOM 5494 O O . ALA D 1 107 ? -24.954 32.412 -35.677 1.00 24.65 ? 88 ALA D O 1 ATOM 5495 C CB . ALA D 1 107 ? -24.112 32.208 -38.500 1.00 23.22 ? 88 ALA D CB 1 ATOM 5496 N N . TYR D 1 108 ? -26.976 32.869 -36.583 1.00 18.46 ? 89 TYR D N 1 ATOM 5497 C CA . TYR D 1 108 ? -27.709 32.569 -35.359 1.00 17.08 ? 89 TYR D CA 1 ATOM 5498 C C . TYR D 1 108 ? -27.547 31.135 -34.874 1.00 16.10 ? 89 TYR D C 1 ATOM 5499 O O . TYR D 1 108 ? -27.657 30.874 -33.688 1.00 17.10 ? 89 TYR D O 1 ATOM 5500 C CB . TYR D 1 108 ? -29.192 32.888 -35.545 1.00 22.91 ? 89 TYR D CB 1 ATOM 5501 C CG . TYR D 1 108 ? -29.526 34.348 -35.390 1.00 20.90 ? 89 TYR D CG 1 ATOM 5502 C CD1 . TYR D 1 108 ? -29.153 35.273 -36.359 1.00 25.30 ? 89 TYR D CD1 1 ATOM 5503 C CD2 . TYR D 1 108 ? -30.214 34.804 -34.276 1.00 20.28 ? 89 TYR D CD2 1 ATOM 5504 C CE1 . TYR D 1 108 ? -29.456 36.623 -36.217 1.00 27.33 ? 89 TYR D CE1 1 ATOM 5505 C CE2 . TYR D 1 108 ? -30.530 36.142 -34.119 1.00 20.24 ? 89 TYR D CE2 1 ATOM 5506 C CZ . TYR D 1 108 ? -30.156 37.053 -35.096 1.00 24.93 ? 89 TYR D CZ 1 ATOM 5507 O OH . TYR D 1 108 ? -30.474 38.393 -34.962 1.00 19.32 ? 89 TYR D OH 1 ATOM 5508 N N . ASN D 1 109 ? -27.309 30.197 -35.786 1.00 23.71 ? 90 ASN D N 1 ATOM 5509 C CA . ASN D 1 109 ? -27.160 28.784 -35.392 1.00 27.75 ? 90 ASN D CA 1 ATOM 5510 C C . ASN D 1 109 ? -25.720 28.267 -35.514 1.00 24.13 ? 90 ASN D C 1 ATOM 5511 O O . ASN D 1 109 ? -25.472 27.060 -35.621 1.00 23.33 ? 90 ASN D O 1 ATOM 5512 C CB . ASN D 1 109 ? -28.148 27.868 -36.147 1.00 21.46 ? 90 ASN D CB 1 ATOM 5513 C CG . ASN D 1 109 ? -28.002 27.956 -37.668 1.00 30.50 ? 90 ASN D CG 1 ATOM 5514 O OD1 . ASN D 1 109 ? -27.985 29.049 -38.250 1.00 31.19 ? 90 ASN D OD1 1 ATOM 5515 N ND2 . ASN D 1 109 ? -27.895 26.794 -38.319 1.00 34.73 ? 90 ASN D ND2 1 ATOM 5516 N N . ALA D 1 110 ? -24.771 29.197 -35.492 1.00 22.40 ? 91 ALA D N 1 ATOM 5517 C CA . ALA D 1 110 ? -23.358 28.841 -35.473 1.00 21.65 ? 91 ALA D CA 1 ATOM 5518 C C . ALA D 1 110 ? -22.995 28.349 -34.067 1.00 21.56 ? 91 ALA D C 1 ATOM 5519 O O . ALA D 1 110 ? -23.522 28.854 -33.072 1.00 20.52 ? 91 ALA D O 1 ATOM 5520 C CB . ALA D 1 110 ? -22.515 30.036 -35.869 1.00 19.81 ? 91 ALA D CB 1 ATOM 5521 N N . ILE D 1 111 ? -22.121 27.353 -33.979 1.00 19.13 ? 92 ILE D N 1 ATOM 5522 C CA . ILE D 1 111 ? -21.694 26.872 -32.671 1.00 21.80 ? 92 ILE D CA 1 ATOM 5523 C C . ILE D 1 111 ? -20.177 27.003 -32.489 1.00 23.86 ? 92 ILE D C 1 ATOM 5524 O O . ILE D 1 111 ? -19.590 26.445 -31.562 1.00 23.76 ? 92 ILE D O 1 ATOM 5525 C CB . ILE D 1 111 ? -22.160 25.443 -32.404 1.00 22.91 ? 92 ILE D CB 1 ATOM 5526 C CG1 . ILE D 1 111 ? -21.685 24.520 -33.521 1.00 23.75 ? 92 ILE D CG1 1 ATOM 5527 C CG2 . ILE D 1 111 ? -23.665 25.403 -32.264 1.00 20.40 ? 92 ILE D CG2 1 ATOM 5528 C CD1 . ILE D 1 111 ? -22.032 23.061 -33.298 1.00 29.38 ? 92 ILE D CD1 1 ATOM 5529 N N . SER D 1 112 ? -19.557 27.757 -33.388 1.00 21.00 ? 93 SER D N 1 ATOM 5530 C CA . SER D 1 112 ? -18.162 28.141 -33.246 1.00 22.85 ? 93 SER D CA 1 ATOM 5531 C C . SER D 1 112 ? -18.022 29.519 -33.872 1.00 22.56 ? 93 SER D C 1 ATOM 5532 O O . SER D 1 112 ? -18.852 29.900 -34.707 1.00 19.47 ? 93 SER D O 1 ATOM 5533 C CB . SER D 1 112 ? -17.284 27.138 -33.979 1.00 23.55 ? 93 SER D CB 1 ATOM 5534 O OG . SER D 1 112 ? -17.458 27.266 -35.377 1.00 27.30 ? 93 SER D OG 1 ATOM 5535 N N . LYS D 1 113 ? -16.996 30.278 -33.488 1.00 23.42 ? 94 LYS D N 1 ATOM 5536 C CA . LYS D 1 113 ? -16.822 31.603 -34.113 1.00 27.71 ? 94 LYS D CA 1 ATOM 5537 C C . LYS D 1 113 ? -16.297 31.470 -35.537 1.00 21.93 ? 94 LYS D C 1 ATOM 5538 O O . LYS D 1 113 ? -15.648 30.475 -35.873 1.00 25.75 ? 94 LYS D O 1 ATOM 5539 C CB . LYS D 1 113 ? -15.958 32.556 -33.266 1.00 34.43 ? 94 LYS D CB 1 ATOM 5540 C CG . LYS D 1 113 ? -14.509 32.144 -33.069 1.00 40.17 ? 94 LYS D CG 1 ATOM 5541 C CD . LYS D 1 113 ? -13.863 33.013 -31.973 1.00 46.36 ? 94 LYS D CD 1 ATOM 5542 C CE . LYS D 1 113 ? -14.087 34.503 -32.239 1.00 45.18 ? 94 LYS D CE 1 ATOM 5543 N NZ . LYS D 1 113 ? -13.247 35.382 -31.356 1.00 53.53 ? 94 LYS D NZ 1 ATOM 5544 N N . PRO D 1 114 ? -16.601 32.457 -36.389 1.00 21.44 ? 95 PRO D N 1 ATOM 5545 C CA . PRO D 1 114 ? -16.134 32.325 -37.774 1.00 19.66 ? 95 PRO D CA 1 ATOM 5546 C C . PRO D 1 114 ? -14.602 32.279 -37.795 1.00 23.57 ? 95 PRO D C 1 ATOM 5547 O O . PRO D 1 114 ? -13.960 33.075 -37.108 1.00 31.44 ? 95 PRO D O 1 ATOM 5548 C CB . PRO D 1 114 ? -16.631 33.625 -38.439 1.00 15.38 ? 95 PRO D CB 1 ATOM 5549 C CG . PRO D 1 114 ? -17.663 34.201 -37.493 1.00 14.35 ? 95 PRO D CG 1 ATOM 5550 C CD . PRO D 1 114 ? -17.303 33.737 -36.139 1.00 17.85 ? 95 PRO D CD 1 ATOM 5551 N N . GLU D 1 115 ? -14.025 31.351 -38.546 1.00 21.63 ? 96 GLU D N 1 ATOM 5552 C CA . GLU D 1 115 ? -12.581 31.342 -38.792 1.00 23.96 ? 96 GLU D CA 1 ATOM 5553 C C . GLU D 1 115 ? -12.321 31.962 -40.173 1.00 25.67 ? 96 GLU D C 1 ATOM 5554 O O . GLU D 1 115 ? -12.646 31.360 -41.217 1.00 25.02 ? 96 GLU D O 1 ATOM 5555 C CB . GLU D 1 115 ? -12.060 29.909 -38.761 1.00 22.39 ? 96 GLU D CB 1 ATOM 5556 C CG . GLU D 1 115 ? -10.560 29.751 -38.826 1.00 22.94 ? 96 GLU D CG 1 ATOM 5557 C CD . GLU D 1 115 ? -10.169 28.275 -38.734 1.00 55.53 ? 96 GLU D CD 1 ATOM 5558 O OE1 . GLU D 1 115 ? -11.038 27.461 -38.303 1.00 59.83 ? 96 GLU D OE1 1 ATOM 5559 O OE2 . GLU D 1 115 ? -9.013 27.926 -39.106 1.00 58.88 ? 96 GLU D OE2 1 ATOM 5560 N N . VAL D 1 116 ? -11.757 33.168 -40.196 1.00 21.33 ? 97 VAL D N 1 ATOM 5561 C CA . VAL D 1 116 ? -11.524 33.847 -41.480 1.00 25.76 ? 97 VAL D CA 1 ATOM 5562 C C . VAL D 1 116 ? -10.244 33.404 -42.219 1.00 18.40 ? 97 VAL D C 1 ATOM 5563 O O . VAL D 1 116 ? -9.141 33.635 -41.762 1.00 24.21 ? 97 VAL D O 1 ATOM 5564 C CB . VAL D 1 116 ? -11.563 35.364 -41.320 1.00 21.93 ? 97 VAL D CB 1 ATOM 5565 C CG1 . VAL D 1 116 ? -11.426 36.034 -42.676 1.00 25.33 ? 97 VAL D CG1 1 ATOM 5566 C CG2 . VAL D 1 116 ? -12.861 35.743 -40.657 1.00 18.56 ? 97 VAL D CG2 1 ATOM 5567 N N . LEU D 1 117 ? -10.414 32.767 -43.368 1.00 18.27 ? 98 LEU D N 1 ATOM 5568 C CA . LEU D 1 117 ? -9.301 32.148 -44.070 1.00 18.73 ? 98 LEU D CA 1 ATOM 5569 C C . LEU D 1 117 ? -8.498 33.118 -44.962 1.00 23.70 ? 98 LEU D C 1 ATOM 5570 O O . LEU D 1 117 ? -7.346 32.870 -45.289 1.00 23.75 ? 98 LEU D O 1 ATOM 5571 C CB . LEU D 1 117 ? -9.828 30.983 -44.900 1.00 19.85 ? 98 LEU D CB 1 ATOM 5572 C CG . LEU D 1 117 ? -10.526 29.844 -44.130 1.00 22.94 ? 98 LEU D CG 1 ATOM 5573 C CD1 . LEU D 1 117 ? -10.990 28.722 -45.068 1.00 14.36 ? 98 LEU D CD1 1 ATOM 5574 C CD2 . LEU D 1 117 ? -9.659 29.281 -43.009 1.00 17.82 ? 98 LEU D CD2 1 ATOM 5575 N N . THR D 1 118 ? -9.101 34.236 -45.339 1.00 19.59 ? 99 THR D N 1 ATOM 5576 C CA . THR D 1 118 ? -8.510 35.099 -46.348 1.00 19.19 ? 99 THR D CA 1 ATOM 5577 C C . THR D 1 118 ? -8.079 36.434 -45.750 1.00 26.91 ? 99 THR D C 1 ATOM 5578 O O . THR D 1 118 ? -8.484 36.755 -44.624 1.00 25.24 ? 99 THR D O 1 ATOM 5579 C CB . THR D 1 118 ? -9.521 35.332 -47.474 1.00 26.10 ? 99 THR D CB 1 ATOM 5580 O OG1 . THR D 1 118 ? -10.795 35.697 -46.897 1.00 29.52 ? 99 THR D OG1 1 ATOM 5581 C CG2 . THR D 1 118 ? -9.651 34.067 -48.335 1.00 19.94 ? 99 THR D CG2 1 ATOM 5582 N N . PRO D 1 119 ? -7.247 37.211 -46.493 1.00 26.78 ? 100 PRO D N 1 ATOM 5583 C CA . PRO D 1 119 ? -6.893 38.596 -46.128 1.00 26.62 ? 100 PRO D CA 1 ATOM 5584 C C . PRO D 1 119 ? -8.146 39.437 -45.879 1.00 26.35 ? 100 PRO D C 1 ATOM 5585 O O . PRO D 1 119 ? -9.148 39.284 -46.609 1.00 27.04 ? 100 PRO D O 1 ATOM 5586 C CB . PRO D 1 119 ? -6.193 39.117 -47.385 1.00 20.27 ? 100 PRO D CB 1 ATOM 5587 C CG . PRO D 1 119 ? -5.595 37.915 -48.005 1.00 19.03 ? 100 PRO D CG 1 ATOM 5588 C CD . PRO D 1 119 ? -6.517 36.759 -47.693 1.00 20.60 ? 100 PRO D CD 1 ATOM 5589 N N . GLN D 1 120 ? -8.103 40.307 -44.877 1.00 19.36 ? 101 GLN D N 1 ATOM 5590 C CA . GLN D 1 120 ? -9.307 41.048 -44.517 1.00 23.65 ? 101 GLN D CA 1 ATOM 5591 C C . GLN D 1 120 ? -9.426 42.416 -45.212 1.00 21.04 ? 101 GLN D C 1 ATOM 5592 O O . GLN D 1 120 ? -9.407 43.469 -44.568 1.00 23.17 ? 101 GLN D O 1 ATOM 5593 C CB . GLN D 1 120 ? -9.467 41.115 -42.992 1.00 19.35 ? 101 GLN D CB 1 ATOM 5594 C CG . GLN D 1 120 ? -9.829 39.767 -42.394 1.00 23.90 ? 101 GLN D CG 1 ATOM 5595 C CD . GLN D 1 120 ? -9.879 39.740 -40.869 1.00 27.31 ? 101 GLN D CD 1 ATOM 5596 O OE1 . GLN D 1 120 ? -10.340 40.684 -40.220 1.00 34.22 ? 101 GLN D OE1 1 ATOM 5597 N NE2 . GLN D 1 120 ? -9.418 38.636 -40.291 1.00 27.67 ? 101 GLN D NE2 1 ATOM 5598 N N . LEU D 1 121 ? -9.554 42.373 -46.538 1.00 20.12 ? 102 LEU D N 1 ATOM 5599 C CA . LEU D 1 121 ? -9.695 43.577 -47.364 1.00 20.55 ? 102 LEU D CA 1 ATOM 5600 C C . LEU D 1 121 ? -11.074 43.665 -48.020 1.00 18.02 ? 102 LEU D C 1 ATOM 5601 O O . LEU D 1 121 ? -11.666 42.657 -48.408 1.00 14.23 ? 102 LEU D O 1 ATOM 5602 C CB . LEU D 1 121 ? -8.631 43.605 -48.460 1.00 21.10 ? 102 LEU D CB 1 ATOM 5603 C CG . LEU D 1 121 ? -7.191 43.542 -47.963 1.00 20.54 ? 102 LEU D CG 1 ATOM 5604 C CD1 . LEU D 1 121 ? -6.200 43.514 -49.118 1.00 23.49 ? 102 LEU D CD1 1 ATOM 5605 C CD2 . LEU D 1 121 ? -6.925 44.718 -47.060 1.00 19.61 ? 102 LEU D CD2 1 ATOM 5606 N N . ALA D 1 122 ? -11.579 44.886 -48.132 1.00 19.71 ? 103 ALA D N 1 ATOM 5607 C CA . ALA D 1 122 ? -12.828 45.152 -48.832 1.00 17.98 ? 103 ALA D CA 1 ATOM 5608 C C . ALA D 1 122 ? -12.551 45.903 -50.144 1.00 20.96 ? 103 ALA D C 1 ATOM 5609 O O . ALA D 1 122 ? -11.581 46.681 -50.259 1.00 21.61 ? 103 ALA D O 1 ATOM 5610 C CB . ALA D 1 122 ? -13.758 45.952 -47.945 1.00 13.73 ? 103 ALA D CB 1 ATOM 5611 N N . HIS D 1 123 ? -13.408 45.668 -51.129 1.00 21.57 ? 104 HIS D N 1 ATOM 5612 C CA . HIS D 1 123 ? -13.308 46.320 -52.429 1.00 19.99 ? 104 HIS D CA 1 ATOM 5613 C C . HIS D 1 123 ? -14.189 47.570 -52.391 1.00 17.10 ? 104 HIS D C 1 ATOM 5614 O O . HIS D 1 123 ? -15.350 47.486 -52.002 1.00 14.79 ? 104 HIS D O 1 ATOM 5615 C CB . HIS D 1 123 ? -13.777 45.348 -53.502 1.00 19.62 ? 104 HIS D CB 1 ATOM 5616 C CG . HIS D 1 123 ? -13.417 45.757 -54.887 1.00 26.85 ? 104 HIS D CG 1 ATOM 5617 N ND1 . HIS D 1 123 ? -14.329 46.318 -55.754 1.00 30.05 ? 104 HIS D ND1 1 ATOM 5618 C CD2 . HIS D 1 123 ? -12.244 45.674 -55.569 1.00 33.88 ? 104 HIS D CD2 1 ATOM 5619 C CE1 . HIS D 1 123 ? -13.736 46.574 -56.910 1.00 37.99 ? 104 HIS D CE1 1 ATOM 5620 N NE2 . HIS D 1 123 ? -12.470 46.194 -56.819 1.00 42.87 ? 104 HIS D NE2 1 ATOM 5621 N N . VAL D 1 124 ? -13.635 48.728 -52.755 1.00 19.08 ? 105 VAL D N 1 ATOM 5622 C CA . VAL D 1 124 ? -14.395 49.980 -52.746 1.00 17.01 ? 105 VAL D CA 1 ATOM 5623 C C . VAL D 1 124 ? -14.341 50.619 -54.109 1.00 20.76 ? 105 VAL D C 1 ATOM 5624 O O . VAL D 1 124 ? -13.268 50.809 -54.665 1.00 23.37 ? 105 VAL D O 1 ATOM 5625 C CB . VAL D 1 124 ? -13.841 51.009 -51.744 1.00 16.65 ? 105 VAL D CB 1 ATOM 5626 C CG1 . VAL D 1 124 ? -14.771 52.191 -51.639 1.00 17.16 ? 105 VAL D CG1 1 ATOM 5627 C CG2 . VAL D 1 124 ? -13.660 50.402 -50.382 1.00 22.93 ? 105 VAL D CG2 1 ATOM 5628 N N . VAL D 1 125 ? -15.510 50.960 -54.637 1.00 27.55 ? 106 VAL D N 1 ATOM 5629 C CA . VAL D 1 125 ? -15.636 51.619 -55.940 1.00 31.16 ? 106 VAL D CA 1 ATOM 5630 C C . VAL D 1 125 ? -15.879 53.123 -55.701 1.00 27.26 ? 106 VAL D C 1 ATOM 5631 O O . VAL D 1 125 ? -16.445 53.500 -54.673 1.00 22.44 ? 106 VAL D O 1 ATOM 5632 C CB . VAL D 1 125 ? -16.781 50.962 -56.761 1.00 26.87 ? 106 VAL D CB 1 ATOM 5633 C CG1 . VAL D 1 125 ? -17.020 51.705 -58.049 1.00 39.13 ? 106 VAL D CG1 1 ATOM 5634 C CG2 . VAL D 1 125 ? -16.445 49.527 -57.058 1.00 24.30 ? 106 VAL D CG2 1 ATOM 5635 N N . SER D 1 126 ? -15.452 53.975 -56.632 1.00 29.13 ? 107 SER D N 1 ATOM 5636 C CA . SER D 1 126 ? -15.558 55.430 -56.459 1.00 28.99 ? 107 SER D CA 1 ATOM 5637 C C . SER D 1 126 ? -16.950 55.960 -56.113 1.00 33.22 ? 107 SER D C 1 ATOM 5638 O O . SER D 1 126 ? -17.059 57.024 -55.501 1.00 30.53 ? 107 SER D O 1 ATOM 5639 C CB . SER D 1 126 ? -15.011 56.173 -57.674 1.00 29.86 ? 107 SER D CB 1 ATOM 5640 O OG . SER D 1 126 ? -15.675 55.750 -58.843 1.00 44.52 ? 107 SER D OG 1 ATOM 5641 N N . ASP D 1 127 ? -18.010 55.238 -56.486 1.00 34.15 ? 108 ASP D N 1 ATOM 5642 C CA . ASP D 1 127 ? -19.366 55.696 -56.141 1.00 30.66 ? 108 ASP D CA 1 ATOM 5643 C C . ASP D 1 127 ? -19.727 55.483 -54.672 1.00 34.88 ? 108 ASP D C 1 ATOM 5644 O O . ASP D 1 127 ? -20.706 56.050 -54.181 1.00 41.60 ? 108 ASP D O 1 ATOM 5645 C CB . ASP D 1 127 ? -20.446 55.090 -57.048 1.00 30.72 ? 108 ASP D CB 1 ATOM 5646 C CG . ASP D 1 127 ? -20.470 53.564 -57.015 1.00 44.34 ? 108 ASP D CG 1 ATOM 5647 O OD1 . ASP D 1 127 ? -19.822 52.966 -56.123 1.00 52.25 ? 108 ASP D OD1 1 ATOM 5648 O OD2 . ASP D 1 127 ? -21.148 52.955 -57.884 1.00 50.76 ? 108 ASP D OD2 1 ATOM 5649 N N . GLY D 1 128 ? -18.939 54.671 -53.971 1.00 32.29 ? 109 GLY D N 1 ATOM 5650 C CA . GLY D 1 128 ? -19.218 54.372 -52.575 1.00 34.03 ? 109 GLY D CA 1 ATOM 5651 C C . GLY D 1 128 ? -19.719 52.959 -52.330 1.00 31.93 ? 109 GLY D C 1 ATOM 5652 O O . GLY D 1 128 ? -20.129 52.646 -51.221 1.00 25.89 ? 109 GLY D O 1 ATOM 5653 N N . GLU D 1 129 ? -19.679 52.114 -53.362 1.00 34.45 ? 110 GLU D N 1 ATOM 5654 C CA . GLU D 1 129 ? -20.090 50.716 -53.248 1.00 27.27 ? 110 GLU D CA 1 ATOM 5655 C C . GLU D 1 129 ? -18.988 49.850 -52.669 1.00 25.61 ? 110 GLU D C 1 ATOM 5656 O O . GLU D 1 129 ? -17.853 49.848 -53.149 1.00 25.21 ? 110 GLU D O 1 ATOM 5657 C CB . GLU D 1 129 ? -20.482 50.159 -54.612 1.00 35.62 ? 110 GLU D CB 1 ATOM 5658 C CG . GLU D 1 129 ? -21.921 50.424 -54.996 1.00 46.68 ? 110 GLU D CG 1 ATOM 5659 C CD . GLU D 1 129 ? -22.908 49.563 -54.217 1.00 57.71 ? 110 GLU D CD 1 ATOM 5660 O OE1 . GLU D 1 129 ? -22.700 48.318 -54.163 1.00 45.92 ? 110 GLU D OE1 1 ATOM 5661 O OE2 . GLU D 1 129 ? -23.886 50.141 -53.666 1.00 64.13 ? 110 GLU D OE2 1 ATOM 5662 N N . VAL D 1 130 ? -19.338 49.089 -51.649 1.00 27.64 ? 111 VAL D N 1 ATOM 5663 C CA . VAL D 1 130 ? -18.359 48.274 -50.953 1.00 23.37 ? 111 VAL D CA 1 ATOM 5664 C C . VAL D 1 130 ? -18.739 46.828 -51.101 1.00 19.27 ? 111 VAL D C 1 ATOM 5665 O O . VAL D 1 130 ? -19.914 46.475 -51.025 1.00 22.02 ? 111 VAL D O 1 ATOM 5666 C CB . VAL D 1 130 ? -18.305 48.641 -49.460 1.00 21.15 ? 111 VAL D CB 1 ATOM 5667 C CG1 . VAL D 1 130 ? -17.233 47.844 -48.749 1.00 14.33 ? 111 VAL D CG1 1 ATOM 5668 C CG2 . VAL D 1 130 ? -18.071 50.144 -49.311 1.00 18.30 ? 111 VAL D CG2 1 ATOM 5669 N N . GLN D 1 131 ? -17.739 45.989 -51.326 1.00 21.95 ? 112 GLN D N 1 ATOM 5670 C CA . GLN D 1 131 ? -17.944 44.547 -51.289 1.00 22.69 ? 112 GLN D CA 1 ATOM 5671 C C . GLN D 1 131 ? -16.879 43.850 -50.430 1.00 19.45 ? 112 GLN D C 1 ATOM 5672 O O . GLN D 1 131 ? -15.676 44.019 -50.637 1.00 17.68 ? 112 GLN D O 1 ATOM 5673 C CB . GLN D 1 131 ? -17.983 43.950 -52.695 1.00 24.42 ? 112 GLN D CB 1 ATOM 5674 C CG . GLN D 1 131 ? -18.233 42.449 -52.696 1.00 28.50 ? 112 GLN D CG 1 ATOM 5675 C CD . GLN D 1 131 ? -18.294 41.872 -54.091 1.00 33.43 ? 112 GLN D CD 1 ATOM 5676 O OE1 . GLN D 1 131 ? -18.845 42.486 -55.001 1.00 39.00 ? 112 GLN D OE1 1 ATOM 5677 N NE2 . GLN D 1 131 ? -17.723 40.683 -54.268 1.00 36.91 ? 112 GLN D NE2 1 ATOM 5678 N N . TYR D 1 132 ? -17.337 43.070 -49.458 1.00 18.25 ? 113 TYR D N 1 ATOM 5679 C CA . TYR D 1 132 ? -16.431 42.326 -48.598 1.00 21.61 ? 113 TYR D CA 1 ATOM 5680 C C . TYR D 1 132 ? -16.803 40.828 -48.654 1.00 22.89 ? 113 TYR D C 1 ATOM 5681 O O . TYR D 1 132 ? -17.902 40.444 -48.250 1.00 22.30 ? 113 TYR D O 1 ATOM 5682 C CB . TYR D 1 132 ? -16.450 42.900 -47.168 1.00 13.33 ? 113 TYR D CB 1 ATOM 5683 C CG . TYR D 1 132 ? -15.608 42.130 -46.182 1.00 16.31 ? 113 TYR D CG 1 ATOM 5684 C CD1 . TYR D 1 132 ? -14.308 41.752 -46.492 1.00 16.88 ? 113 TYR D CD1 1 ATOM 5685 C CD2 . TYR D 1 132 ? -16.112 41.785 -44.933 1.00 17.21 ? 113 TYR D CD2 1 ATOM 5686 C CE1 . TYR D 1 132 ? -13.527 41.032 -45.582 1.00 17.90 ? 113 TYR D CE1 1 ATOM 5687 C CE2 . TYR D 1 132 ? -15.353 41.066 -44.015 1.00 17.96 ? 113 TYR D CE2 1 ATOM 5688 C CZ . TYR D 1 132 ? -14.060 40.684 -44.342 1.00 22.05 ? 113 TYR D CZ 1 ATOM 5689 O OH . TYR D 1 132 ? -13.305 39.966 -43.419 1.00 19.72 ? 113 TYR D OH 1 ATOM 5690 N N . THR D 1 133 ? -15.891 40.006 -49.186 1.00 19.20 ? 114 THR D N 1 ATOM 5691 C CA . THR D 1 133 ? -16.144 38.590 -49.435 1.00 18.58 ? 114 THR D CA 1 ATOM 5692 C C . THR D 1 133 ? -15.064 37.701 -48.805 1.00 20.71 ? 114 THR D C 1 ATOM 5693 O O . THR D 1 133 ? -14.173 37.205 -49.492 1.00 21.39 ? 114 THR D O 1 ATOM 5694 C CB . THR D 1 133 ? -16.215 38.301 -50.946 1.00 18.92 ? 114 THR D CB 1 ATOM 5695 O OG1 . THR D 1 133 ? -17.024 39.292 -51.587 1.00 25.17 ? 114 THR D OG1 1 ATOM 5696 C CG2 . THR D 1 133 ? -16.796 36.925 -51.210 1.00 18.58 ? 114 THR D CG2 1 ATOM 5697 N N . PRO D 1 134 ? -15.130 37.505 -47.479 1.00 21.73 ? 115 PRO D N 1 ATOM 5698 C CA . PRO D 1 134 ? -14.128 36.632 -46.855 1.00 15.35 ? 115 PRO D CA 1 ATOM 5699 C C . PRO D 1 134 ? -14.475 35.172 -47.057 1.00 22.29 ? 115 PRO D C 1 ATOM 5700 O O . PRO D 1 134 ? -15.663 34.825 -47.176 1.00 26.27 ? 115 PRO D O 1 ATOM 5701 C CB . PRO D 1 134 ? -14.259 36.977 -45.368 1.00 17.58 ? 115 PRO D CB 1 ATOM 5702 C CG . PRO D 1 134 ? -15.668 37.499 -45.203 1.00 13.64 ? 115 PRO D CG 1 ATOM 5703 C CD . PRO D 1 134 ? -16.002 38.183 -46.487 1.00 18.73 ? 115 PRO D CD 1 ATOM 5704 N N . SER D 1 135 ? -13.467 34.308 -47.093 1.00 20.59 ? 116 SER D N 1 ATOM 5705 C CA . SER D 1 135 ? -13.745 32.866 -47.030 1.00 23.21 ? 116 SER D CA 1 ATOM 5706 C C . SER D 1 135 ? -13.780 32.395 -45.565 1.00 22.96 ? 116 SER D C 1 ATOM 5707 O O . SER D 1 135 ? -12.833 32.628 -44.805 1.00 22.56 ? 116 SER D O 1 ATOM 5708 C CB . SER D 1 135 ? -12.712 32.073 -47.825 1.00 22.26 ? 116 SER D CB 1 ATOM 5709 O OG . SER D 1 135 ? -13.000 30.690 -47.782 1.00 23.28 ? 116 SER D OG 1 ATOM 5710 N N . ILE D 1 136 ? -14.862 31.724 -45.172 1.00 17.49 ? 117 ILE D N 1 ATOM 5711 C CA . ILE D 1 136 ? -15.058 31.375 -43.766 1.00 18.92 ? 117 ILE D CA 1 ATOM 5712 C C . ILE D 1 136 ? -15.272 29.884 -43.525 1.00 18.73 ? 117 ILE D C 1 ATOM 5713 O O . ILE D 1 136 ? -16.085 29.254 -44.196 1.00 22.92 ? 117 ILE D O 1 ATOM 5714 C CB . ILE D 1 136 ? -16.264 32.159 -43.197 1.00 23.88 ? 117 ILE D CB 1 ATOM 5715 C CG1 . ILE D 1 136 ? -15.953 33.670 -43.189 1.00 23.16 ? 117 ILE D CG1 1 ATOM 5716 C CG2 . ILE D 1 136 ? -16.641 31.649 -41.813 1.00 19.52 ? 117 ILE D CG2 1 ATOM 5717 C CD1 . ILE D 1 136 ? -17.126 34.549 -42.806 1.00 21.65 ? 117 ILE D CD1 1 ATOM 5718 N N . ARG D 1 137 ? -14.545 29.314 -42.571 1.00 17.48 ? 118 ARG D N 1 ATOM 5719 C CA . ARG D 1 137 ? -14.868 27.974 -42.073 1.00 19.55 ? 118 ARG D CA 1 ATOM 5720 C C . ARG D 1 137 ? -15.624 28.063 -40.738 1.00 20.57 ? 118 ARG D C 1 ATOM 5721 O O . ARG D 1 137 ? -15.119 28.645 -39.777 1.00 23.24 ? 118 ARG D O 1 ATOM 5722 C CB . ARG D 1 137 ? -13.603 27.144 -41.894 1.00 18.41 ? 118 ARG D CB 1 ATOM 5723 C CG . ARG D 1 137 ? -13.855 25.868 -41.146 1.00 23.88 ? 118 ARG D CG 1 ATOM 5724 C CD . ARG D 1 137 ? -12.746 24.864 -41.314 1.00 28.68 ? 118 ARG D CD 1 ATOM 5725 N NE . ARG D 1 137 ? -13.095 23.569 -40.708 1.00 40.52 ? 118 ARG D NE 1 ATOM 5726 C CZ . ARG D 1 137 ? -12.371 22.456 -40.819 1.00 38.51 ? 118 ARG D CZ 1 ATOM 5727 N NH1 . ARG D 1 137 ? -11.242 22.453 -41.530 1.00 34.08 ? 118 ARG D NH1 1 ATOM 5728 N NH2 . ARG D 1 137 ? -12.791 21.338 -40.240 1.00 36.78 ? 118 ARG D NH2 1 ATOM 5729 N N . GLN D 1 138 ? -16.823 27.487 -40.673 1.00 16.38 ? 119 GLN D N 1 ATOM 5730 C CA . GLN D 1 138 ? -17.644 27.574 -39.455 1.00 23.54 ? 119 GLN D CA 1 ATOM 5731 C C . GLN D 1 138 ? -18.442 26.290 -39.174 1.00 24.87 ? 119 GLN D C 1 ATOM 5732 O O . GLN D 1 138 ? -18.855 25.590 -40.099 1.00 26.38 ? 119 GLN D O 1 ATOM 5733 C CB . GLN D 1 138 ? -18.592 28.795 -39.521 1.00 22.48 ? 119 GLN D CB 1 ATOM 5734 C CG . GLN D 1 138 ? -19.172 29.241 -38.169 1.00 20.56 ? 119 GLN D CG 1 ATOM 5735 C CD . GLN D 1 138 ? -19.670 30.674 -38.221 1.00 20.59 ? 119 GLN D CD 1 ATOM 5736 O OE1 . GLN D 1 138 ? -19.995 31.170 -39.298 1.00 18.06 ? 119 GLN D OE1 1 ATOM 5737 N NE2 . GLN D 1 138 ? -19.721 31.354 -37.062 1.00 21.36 ? 119 GLN D NE2 1 ATOM 5738 N N . ARG D 1 139 ? -18.663 25.991 -37.898 1.00 20.20 ? 120 ARG D N 1 ATOM 5739 C CA . ARG D 1 139 ? -19.486 24.848 -37.501 1.00 21.18 ? 120 ARG D CA 1 ATOM 5740 C C . ARG D 1 139 ? -20.942 25.280 -37.152 1.00 24.03 ? 120 ARG D C 1 ATOM 5741 O O . ARG D 1 139 ? -21.168 26.292 -36.471 1.00 21.53 ? 120 ARG D O 1 ATOM 5742 C CB . ARG D 1 139 ? -18.809 24.100 -36.349 1.00 22.83 ? 120 ARG D CB 1 ATOM 5743 C CG . ARG D 1 139 ? -19.366 22.716 -36.121 1.00 30.77 ? 120 ARG D CG 1 ATOM 5744 C CD . ARG D 1 139 ? -18.391 21.772 -35.370 1.00 49.12 ? 120 ARG D CD 1 ATOM 5745 N NE . ARG D 1 139 ? -18.946 20.412 -35.316 1.00 46.51 ? 120 ARG D NE 1 ATOM 5746 C CZ . ARG D 1 139 ? -18.752 19.479 -36.251 1.00 44.01 ? 120 ARG D CZ 1 ATOM 5747 N NH1 . ARG D 1 139 ? -17.983 19.727 -37.302 1.00 43.00 ? 120 ARG D NH1 1 ATOM 5748 N NH2 . ARG D 1 139 ? -19.327 18.288 -36.140 1.00 46.55 ? 120 ARG D NH2 1 ATOM 5749 N N . PHE D 1 140 ? -21.933 24.540 -37.648 1.00 26.30 ? 121 PHE D N 1 ATOM 5750 C CA . PHE D 1 140 ? -23.339 24.898 -37.408 1.00 21.23 ? 121 PHE D CA 1 ATOM 5751 C C . PHE D 1 140 ? -24.139 23.779 -36.788 1.00 26.28 ? 121 PHE D C 1 ATOM 5752 O O . PHE D 1 140 ? -23.743 22.615 -36.832 1.00 30.16 ? 121 PHE D O 1 ATOM 5753 C CB . PHE D 1 140 ? -24.041 25.283 -38.699 1.00 20.74 ? 121 PHE D CB 1 ATOM 5754 C CG . PHE D 1 140 ? -23.460 26.472 -39.359 1.00 23.55 ? 121 PHE D CG 1 ATOM 5755 C CD1 . PHE D 1 140 ? -22.412 26.332 -40.254 1.00 19.43 ? 121 PHE D CD1 1 ATOM 5756 C CD2 . PHE D 1 140 ? -23.956 27.745 -39.084 1.00 24.89 ? 121 PHE D CD2 1 ATOM 5757 C CE1 . PHE D 1 140 ? -21.862 27.446 -40.871 1.00 21.29 ? 121 PHE D CE1 1 ATOM 5758 C CE2 . PHE D 1 140 ? -23.408 28.871 -39.695 1.00 21.15 ? 121 PHE D CE2 1 ATOM 5759 C CZ . PHE D 1 140 ? -22.357 28.724 -40.590 1.00 18.47 ? 121 PHE D CZ 1 ATOM 5760 N N . SER D 1 141 ? -25.287 24.150 -36.232 1.00 27.89 ? 122 SER D N 1 ATOM 5761 C CA . SER D 1 141 ? -26.249 23.199 -35.692 1.00 28.18 ? 122 SER D CA 1 ATOM 5762 C C . SER D 1 141 ? -27.493 23.222 -36.580 1.00 30.60 ? 122 SER D C 1 ATOM 5763 O O . SER D 1 141 ? -28.171 24.245 -36.690 1.00 28.98 ? 122 SER D O 1 ATOM 5764 C CB . SER D 1 141 ? -26.609 23.582 -34.259 1.00 32.79 ? 122 SER D CB 1 ATOM 5765 O OG . SER D 1 141 ? -27.838 22.996 -33.865 1.00 44.14 ? 122 SER D OG 1 ATOM 5766 N N . CYS D 1 142 ? -27.784 22.097 -37.222 1.00 36.34 ? 123 CYS D N 1 ATOM 5767 C CA . CYS D 1 142 ? -28.894 22.037 -38.170 1.00 42.04 ? 123 CYS D CA 1 ATOM 5768 C C . CYS D 1 142 ? -29.357 20.612 -38.419 1.00 40.12 ? 123 CYS D C 1 ATOM 5769 O O . CYS D 1 142 ? -28.788 19.672 -37.869 1.00 41.10 ? 123 CYS D O 1 ATOM 5770 C CB . CYS D 1 142 ? -28.500 22.703 -39.492 1.00 44.99 ? 123 CYS D CB 1 ATOM 5771 S SG . CYS D 1 142 ? -26.950 22.080 -40.211 1.00 59.70 ? 123 CYS D SG 1 ATOM 5772 N N . ASP D 1 143 ? -30.379 20.458 -39.260 1.00 37.75 ? 124 ASP D N 1 ATOM 5773 C CA . ASP D 1 143 ? -30.949 19.139 -39.532 1.00 40.70 ? 124 ASP D CA 1 ATOM 5774 C C . ASP D 1 143 ? -30.110 18.356 -40.549 1.00 39.95 ? 124 ASP D C 1 ATOM 5775 O O . ASP D 1 143 ? -30.006 18.752 -41.716 1.00 36.66 ? 124 ASP D O 1 ATOM 5776 C CB . ASP D 1 143 ? -32.390 19.277 -40.022 1.00 46.94 ? 124 ASP D CB 1 ATOM 5777 C CG . ASP D 1 143 ? -33.195 17.989 -39.876 1.00 43.01 ? 124 ASP D CG 1 ATOM 5778 O OD1 . ASP D 1 143 ? -32.691 17.024 -39.250 1.00 41.18 ? 124 ASP D OD1 1 ATOM 5779 O OD2 . ASP D 1 143 ? -34.344 17.960 -40.378 1.00 36.81 ? 124 ASP D OD2 1 ATOM 5780 N N . VAL D 1 144 ? -29.529 17.244 -40.088 1.00 32.91 ? 125 VAL D N 1 ATOM 5781 C CA . VAL D 1 144 ? -28.575 16.459 -40.864 1.00 33.72 ? 125 VAL D CA 1 ATOM 5782 C C . VAL D 1 144 ? -29.173 15.117 -41.317 1.00 41.76 ? 125 VAL D C 1 ATOM 5783 O O . VAL D 1 144 ? -28.620 14.424 -42.178 1.00 42.94 ? 125 VAL D O 1 ATOM 5784 C CB . VAL D 1 144 ? -27.303 16.214 -40.035 1.00 37.19 ? 125 VAL D CB 1 ATOM 5785 C CG1 . VAL D 1 144 ? -26.268 15.451 -40.825 1.00 31.59 ? 125 VAL D CG1 1 ATOM 5786 C CG2 . VAL D 1 144 ? -26.729 17.531 -39.562 1.00 38.83 ? 125 VAL D CG2 1 ATOM 5787 N N . SER D 1 145 ? -30.312 14.758 -40.733 1.00 45.16 ? 126 SER D N 1 ATOM 5788 C CA . SER D 1 145 ? -31.002 13.508 -41.059 1.00 44.86 ? 126 SER D CA 1 ATOM 5789 C C . SER D 1 145 ? -31.225 13.331 -42.573 1.00 51.30 ? 126 SER D C 1 ATOM 5790 O O . SER D 1 145 ? -31.692 14.255 -43.273 1.00 47.26 ? 126 SER D O 1 ATOM 5791 C CB . SER D 1 145 ? -32.345 13.448 -40.332 1.00 39.44 ? 126 SER D CB 1 ATOM 5792 O OG . SER D 1 145 ? -33.192 14.508 -40.753 1.00 40.30 ? 126 SER D OG 1 ATOM 5793 N N . GLY D 1 146 ? -30.882 12.143 -43.072 1.00 48.56 ? 127 GLY D N 1 ATOM 5794 C CA . GLY D 1 146 ? -31.084 11.818 -44.473 1.00 45.99 ? 127 GLY D CA 1 ATOM 5795 C C . GLY D 1 146 ? -29.918 12.241 -45.337 1.00 39.38 ? 127 GLY D C 1 ATOM 5796 O O . GLY D 1 146 ? -30.027 12.371 -46.551 1.00 38.54 ? 127 GLY D O 1 ATOM 5797 N N . VAL D 1 147 ? -28.781 12.454 -44.700 1.00 42.12 ? 128 VAL D N 1 ATOM 5798 C CA . VAL D 1 147 ? -27.600 12.861 -45.431 1.00 39.22 ? 128 VAL D CA 1 ATOM 5799 C C . VAL D 1 147 ? -27.098 11.702 -46.291 1.00 40.31 ? 128 VAL D C 1 ATOM 5800 O O . VAL D 1 147 ? -26.476 11.923 -47.333 1.00 45.83 ? 128 VAL D O 1 ATOM 5801 C CB . VAL D 1 147 ? -26.502 13.394 -44.475 1.00 35.84 ? 128 VAL D CB 1 ATOM 5802 C CG1 . VAL D 1 147 ? -26.098 12.331 -43.443 1.00 33.93 ? 128 VAL D CG1 1 ATOM 5803 C CG2 . VAL D 1 147 ? -25.303 13.892 -45.266 1.00 37.80 ? 128 VAL D CG2 1 ATOM 5804 N N . ASP D 1 148 ? -27.389 10.473 -45.858 1.00 44.52 ? 129 ASP D N 1 ATOM 5805 C CA . ASP D 1 148 ? -26.937 9.276 -46.564 1.00 45.00 ? 129 ASP D CA 1 ATOM 5806 C C . ASP D 1 148 ? -28.060 8.649 -47.417 1.00 37.49 ? 129 ASP D C 1 ATOM 5807 O O . ASP D 1 148 ? -28.135 7.446 -47.573 1.00 38.32 ? 129 ASP D O 1 ATOM 5808 C CB . ASP D 1 148 ? -26.343 8.273 -45.565 1.00 49.72 ? 129 ASP D CB 1 ATOM 5809 C CG . ASP D 1 148 ? -25.161 7.481 -46.153 1.00 74.00 ? 129 ASP D CG 1 ATOM 5810 O OD1 . ASP D 1 148 ? -25.240 7.056 -47.338 1.00 76.28 ? 129 ASP D OD1 1 ATOM 5811 O OD2 . ASP D 1 148 ? -24.148 7.290 -45.431 1.00 67.55 ? 129 ASP D OD2 1 ATOM 5812 N N . THR D 1 149 ? -28.896 9.508 -47.988 1.00 36.85 ? 130 THR D N 1 ATOM 5813 C CA . THR D 1 149 ? -30.128 9.152 -48.678 1.00 31.79 ? 130 THR D CA 1 ATOM 5814 C C . THR D 1 149 ? -30.132 9.833 -50.045 1.00 46.23 ? 130 THR D C 1 ATOM 5815 O O . THR D 1 149 ? -29.453 10.837 -50.239 1.00 53.57 ? 130 THR D O 1 ATOM 5816 C CB . THR D 1 149 ? -31.330 9.639 -47.841 1.00 36.10 ? 130 THR D CB 1 ATOM 5817 O OG1 . THR D 1 149 ? -31.444 8.823 -46.665 1.00 37.03 ? 130 THR D OG1 1 ATOM 5818 C CG2 . THR D 1 149 ? -32.649 9.616 -48.622 1.00 44.70 ? 130 THR D CG2 1 ATOM 5819 N N . GLU D 1 150 ? -30.883 9.303 -51.000 1.00 49.98 ? 131 GLU D N 1 ATOM 5820 C CA . GLU D 1 150 ? -30.917 9.899 -52.328 1.00 53.48 ? 131 GLU D CA 1 ATOM 5821 C C . GLU D 1 150 ? -31.504 11.322 -52.349 1.00 49.86 ? 131 GLU D C 1 ATOM 5822 O O . GLU D 1 150 ? -31.158 12.126 -53.210 1.00 53.40 ? 131 GLU D O 1 ATOM 5823 C CB . GLU D 1 150 ? -31.682 8.982 -53.281 1.00 71.65 ? 131 GLU D CB 1 ATOM 5824 C CG . GLU D 1 150 ? -31.454 9.259 -54.752 1.00 73.14 ? 131 GLU D CG 1 ATOM 5825 C CD . GLU D 1 150 ? -32.543 8.657 -55.616 1.00 85.93 ? 131 GLU D CD 1 ATOM 5826 O OE1 . GLU D 1 150 ? -33.727 8.716 -55.209 1.00 87.45 ? 131 GLU D OE1 1 ATOM 5827 O OE2 . GLU D 1 150 ? -32.216 8.122 -56.698 1.00 93.00 ? 131 GLU D OE2 1 ATOM 5828 N N . SER D 1 151 ? -32.381 11.638 -51.402 1.00 47.16 ? 132 SER D N 1 ATOM 5829 C CA . SER D 1 151 ? -32.999 12.966 -51.358 1.00 43.22 ? 132 SER D CA 1 ATOM 5830 C C . SER D 1 151 ? -32.211 13.983 -50.506 1.00 43.11 ? 132 SER D C 1 ATOM 5831 O O . SER D 1 151 ? -32.474 15.188 -50.556 1.00 44.95 ? 132 SER D O 1 ATOM 5832 C CB . SER D 1 151 ? -34.444 12.856 -50.867 1.00 42.82 ? 132 SER D CB 1 ATOM 5833 O OG . SER D 1 151 ? -34.502 12.061 -49.694 1.00 62.42 ? 132 SER D OG 1 ATOM 5834 N N . GLY D 1 152 ? -31.263 13.493 -49.712 1.00 41.62 ? 133 GLY D N 1 ATOM 5835 C CA . GLY D 1 152 ? -30.355 14.354 -48.971 1.00 42.03 ? 133 GLY D CA 1 ATOM 5836 C C . GLY D 1 152 ? -30.899 15.031 -47.716 1.00 46.47 ? 133 GLY D C 1 ATOM 5837 O O . GLY D 1 152 ? -32.091 14.954 -47.413 1.00 40.63 ? 133 GLY D O 1 ATOM 5838 N N . ALA D 1 153 ? -30.004 15.696 -46.977 1.00 52.28 ? 134 ALA D N 1 ATOM 5839 C CA . ALA D 1 153 ? -30.382 16.524 -45.826 1.00 42.35 ? 134 ALA D CA 1 ATOM 5840 C C . ALA D 1 153 ? -30.579 17.970 -46.264 1.00 35.78 ? 134 ALA D C 1 ATOM 5841 O O . ALA D 1 153 ? -29.976 18.420 -47.243 1.00 36.29 ? 134 ALA D O 1 ATOM 5842 C CB . ALA D 1 153 ? -29.318 16.453 -44.755 1.00 36.19 ? 134 ALA D CB 1 ATOM 5843 N N . THR D 1 154 ? -31.425 18.696 -45.544 1.00 36.92 ? 135 THR D N 1 ATOM 5844 C CA . THR D 1 154 ? -31.544 20.142 -45.761 1.00 45.62 ? 135 THR D CA 1 ATOM 5845 C C . THR D 1 154 ? -31.193 20.942 -44.505 1.00 45.99 ? 135 THR D C 1 ATOM 5846 O O . THR D 1 154 ? -31.972 21.000 -43.545 1.00 43.31 ? 135 THR D O 1 ATOM 5847 C CB . THR D 1 154 ? -32.940 20.570 -46.263 1.00 48.95 ? 135 THR D CB 1 ATOM 5848 O OG1 . THR D 1 154 ? -33.333 19.744 -47.364 1.00 52.25 ? 135 THR D OG1 1 ATOM 5849 C CG2 . THR D 1 154 ? -32.916 22.035 -46.723 1.00 38.95 ? 135 THR D CG2 1 ATOM 5850 N N . CYS D 1 155 ? -30.008 21.548 -44.540 1.00 41.42 ? 136 CYS D N 1 ATOM 5851 C CA . CYS D 1 155 ? -29.499 22.370 -43.458 1.00 40.57 ? 136 CYS D CA 1 ATOM 5852 C C . CYS D 1 155 ? -29.787 23.871 -43.730 1.00 43.05 ? 136 CYS D C 1 ATOM 5853 O O . CYS D 1 155 ? -29.472 24.371 -44.815 1.00 41.36 ? 136 CYS D O 1 ATOM 5854 C CB . CYS D 1 155 ? -27.998 22.111 -43.304 1.00 31.54 ? 136 CYS D CB 1 ATOM 5855 S SG . CYS D 1 155 ? -27.206 23.072 -41.977 1.00 68.78 ? 136 CYS D SG 1 ATOM 5856 N N . ARG D 1 156 ? -30.407 24.572 -42.772 1.00 37.21 ? 137 ARG D N 1 ATOM 5857 C CA . ARG D 1 156 ? -30.668 26.011 -42.910 1.00 37.58 ? 137 ARG D CA 1 ATOM 5858 C C . ARG D 1 156 ? -29.694 26.865 -42.075 1.00 36.21 ? 137 ARG D C 1 ATOM 5859 O O . ARG D 1 156 ? -29.411 26.551 -40.915 1.00 42.60 ? 137 ARG D O 1 ATOM 5860 C CB . ARG D 1 156 ? -32.110 26.379 -42.525 1.00 39.04 ? 137 ARG D CB 1 ATOM 5861 C CG . ARG D 1 156 ? -33.184 25.412 -42.966 1.00 48.42 ? 137 ARG D CG 1 ATOM 5862 C CD . ARG D 1 156 ? -34.596 25.911 -42.580 1.00 62.20 ? 137 ARG D CD 1 ATOM 5863 N NE . ARG D 1 156 ? -34.661 26.575 -41.267 1.00 67.63 ? 137 ARG D NE 1 ATOM 5864 C CZ . ARG D 1 156 ? -34.929 25.964 -40.105 1.00 66.51 ? 137 ARG D CZ 1 ATOM 5865 N NH1 . ARG D 1 156 ? -35.156 24.654 -40.065 1.00 64.84 ? 137 ARG D NH1 1 ATOM 5866 N NH2 . ARG D 1 156 ? -34.965 26.663 -38.971 1.00 54.79 ? 137 ARG D NH2 1 ATOM 5867 N N . ILE D 1 157 ? -29.197 27.950 -42.664 1.00 26.11 ? 138 ILE D N 1 ATOM 5868 C CA . ILE D 1 157 ? -28.309 28.860 -41.958 1.00 30.04 ? 138 ILE D CA 1 ATOM 5869 C C . ILE D 1 157 ? -28.949 30.232 -41.906 1.00 33.58 ? 138 ILE D C 1 ATOM 5870 O O . ILE D 1 157 ? -29.318 30.791 -42.950 1.00 35.26 ? 138 ILE D O 1 ATOM 5871 C CB . ILE D 1 157 ? -26.944 28.978 -42.648 1.00 26.09 ? 138 ILE D CB 1 ATOM 5872 C CG1 . ILE D 1 157 ? -26.229 27.624 -42.629 1.00 23.11 ? 138 ILE D CG1 1 ATOM 5873 C CG2 . ILE D 1 157 ? -26.116 30.054 -41.971 1.00 19.00 ? 138 ILE D CG2 1 ATOM 5874 C CD1 . ILE D 1 157 ? -24.787 27.687 -43.025 1.00 18.98 ? 138 ILE D CD1 1 ATOM 5875 N N . LYS D 1 158 ? -29.087 30.779 -40.699 1.00 29.05 ? 139 LYS D N 1 ATOM 5876 C CA . LYS D 1 158 ? -29.790 32.053 -40.514 1.00 23.34 ? 139 LYS D CA 1 ATOM 5877 C C . LYS D 1 158 ? -28.804 33.179 -40.200 1.00 22.14 ? 139 LYS D C 1 ATOM 5878 O O . LYS D 1 158 ? -28.113 33.159 -39.169 1.00 22.49 ? 139 LYS D O 1 ATOM 5879 C CB . LYS D 1 158 ? -30.841 31.904 -39.416 1.00 23.35 ? 139 LYS D CB 1 ATOM 5880 C CG . LYS D 1 158 ? -31.559 33.175 -39.044 1.00 29.28 ? 139 LYS D CG 1 ATOM 5881 C CD . LYS D 1 158 ? -32.284 33.006 -37.703 1.00 26.84 ? 139 LYS D CD 1 ATOM 5882 C CE . LYS D 1 158 ? -32.614 34.362 -37.059 1.00 32.05 ? 139 LYS D CE 1 ATOM 5883 N NZ . LYS D 1 158 ? -33.445 34.238 -35.820 1.00 32.40 ? 139 LYS D NZ 1 ATOM 5884 N N . ILE D 1 159 ? -28.733 34.155 -41.099 1.00 20.40 ? 140 ILE D N 1 ATOM 5885 C CA . ILE D 1 159 ? -27.762 35.238 -40.975 1.00 22.35 ? 140 ILE D CA 1 ATOM 5886 C C . ILE D 1 159 ? -28.433 36.603 -40.931 1.00 25.81 ? 140 ILE D C 1 ATOM 5887 O O . ILE D 1 159 ? -29.256 36.908 -41.790 1.00 29.72 ? 140 ILE D O 1 ATOM 5888 C CB . ILE D 1 159 ? -26.797 35.216 -42.144 1.00 17.70 ? 140 ILE D CB 1 ATOM 5889 C CG1 . ILE D 1 159 ? -25.983 33.934 -42.100 1.00 21.92 ? 140 ILE D CG1 1 ATOM 5890 C CG2 . ILE D 1 159 ? -25.878 36.418 -42.100 1.00 23.19 ? 140 ILE D CG2 1 ATOM 5891 C CD1 . ILE D 1 159 ? -24.909 33.857 -43.172 1.00 32.64 ? 140 ILE D CD1 1 ATOM 5892 N N . GLY D 1 160 ? -28.090 37.425 -39.936 1.00 25.97 ? 141 GLY D N 1 ATOM 5893 C CA . GLY D 1 160 ? -28.677 38.756 -39.832 1.00 23.35 ? 141 GLY D CA 1 ATOM 5894 C C . GLY D 1 160 ? -27.875 39.719 -38.985 1.00 21.06 ? 141 GLY D C 1 ATOM 5895 O O . GLY D 1 160 ? -26.876 39.330 -38.373 1.00 21.31 ? 141 GLY D O 1 ATOM 5896 N N . SER D 1 161 ? -28.306 40.980 -38.949 1.00 24.53 ? 142 SER D N 1 ATOM 5897 C CA . SER D 1 161 ? -27.689 41.978 -38.061 1.00 24.03 ? 142 SER D CA 1 ATOM 5898 C C . SER D 1 161 ? -27.914 41.628 -36.588 1.00 23.66 ? 142 SER D C 1 ATOM 5899 O O . SER D 1 161 ? -29.029 41.248 -36.193 1.00 23.32 ? 142 SER D O 1 ATOM 5900 C CB . SER D 1 161 ? -28.245 43.375 -38.332 1.00 19.37 ? 142 SER D CB 1 ATOM 5901 O OG . SER D 1 161 ? -27.712 44.305 -37.415 1.00 20.68 ? 142 SER D OG 1 ATOM 5902 N N . TRP D 1 162 ? -26.869 41.770 -35.775 1.00 16.56 ? 143 TRP D N 1 ATOM 5903 C CA . TRP D 1 162 ? -26.966 41.396 -34.370 1.00 21.51 ? 143 TRP D CA 1 ATOM 5904 C C . TRP D 1 162 ? -27.575 42.493 -33.492 1.00 26.06 ? 143 TRP D C 1 ATOM 5905 O O . TRP D 1 162 ? -28.288 42.193 -32.516 1.00 23.55 ? 143 TRP D O 1 ATOM 5906 C CB . TRP D 1 162 ? -25.605 40.963 -33.807 1.00 20.80 ? 143 TRP D CB 1 ATOM 5907 C CG . TRP D 1 162 ? -25.729 40.196 -32.489 1.00 24.64 ? 143 TRP D CG 1 ATOM 5908 C CD1 . TRP D 1 162 ? -25.408 40.651 -31.228 1.00 24.97 ? 143 TRP D CD1 1 ATOM 5909 C CD2 . TRP D 1 162 ? -26.218 38.856 -32.311 1.00 18.51 ? 143 TRP D CD2 1 ATOM 5910 N NE1 . TRP D 1 162 ? -25.656 39.669 -30.295 1.00 18.82 ? 143 TRP D NE1 1 ATOM 5911 C CE2 . TRP D 1 162 ? -26.154 38.559 -30.935 1.00 16.96 ? 143 TRP D CE2 1 ATOM 5912 C CE3 . TRP D 1 162 ? -26.693 37.872 -33.187 1.00 21.16 ? 143 TRP D CE3 1 ATOM 5913 C CZ2 . TRP D 1 162 ? -26.559 37.337 -30.413 1.00 18.74 ? 143 TRP D CZ2 1 ATOM 5914 C CZ3 . TRP D 1 162 ? -27.087 36.644 -32.670 1.00 16.96 ? 143 TRP D CZ3 1 ATOM 5915 C CH2 . TRP D 1 162 ? -27.016 36.388 -31.297 1.00 16.34 ? 143 TRP D CH2 1 ATOM 5916 N N . THR D 1 163 ? -27.288 43.753 -33.833 1.00 21.60 ? 144 THR D N 1 ATOM 5917 C CA . THR D 1 163 ? -27.716 44.874 -33.001 1.00 20.35 ? 144 THR D CA 1 ATOM 5918 C C . THR D 1 163 ? -28.543 45.939 -33.712 1.00 22.03 ? 144 THR D C 1 ATOM 5919 O O . THR D 1 163 ? -29.055 46.850 -33.064 1.00 27.14 ? 144 THR D O 1 ATOM 5920 C CB . THR D 1 163 ? -26.530 45.592 -32.347 1.00 19.46 ? 144 THR D CB 1 ATOM 5921 O OG1 . THR D 1 163 ? -25.739 46.195 -33.374 1.00 21.29 ? 144 THR D OG1 1 ATOM 5922 C CG2 . THR D 1 163 ? -25.692 44.636 -31.534 1.00 16.11 ? 144 THR D CG2 1 ATOM 5923 N N . HIS D 1 164 ? -28.663 45.857 -35.030 1.00 22.00 ? 145 HIS D N 1 ATOM 5924 C CA . HIS D 1 164 ? -29.427 46.872 -35.767 1.00 22.57 ? 145 HIS D CA 1 ATOM 5925 C C . HIS D 1 164 ? -30.765 46.349 -36.283 1.00 25.67 ? 145 HIS D C 1 ATOM 5926 O O . HIS D 1 164 ? -30.805 45.342 -36.984 1.00 21.86 ? 145 HIS D O 1 ATOM 5927 C CB . HIS D 1 164 ? -28.611 47.420 -36.930 1.00 22.86 ? 145 HIS D CB 1 ATOM 5928 C CG . HIS D 1 164 ? -27.400 48.197 -36.511 1.00 25.01 ? 145 HIS D CG 1 ATOM 5929 N ND1 . HIS D 1 164 ? -27.485 49.443 -35.925 1.00 28.63 ? 145 HIS D ND1 1 ATOM 5930 C CD2 . HIS D 1 164 ? -26.079 47.916 -36.611 1.00 24.91 ? 145 HIS D CD2 1 ATOM 5931 C CE1 . HIS D 1 164 ? -26.267 49.894 -35.677 1.00 27.13 ? 145 HIS D CE1 1 ATOM 5932 N NE2 . HIS D 1 164 ? -25.396 48.989 -36.083 1.00 28.01 ? 145 HIS D NE2 1 ATOM 5933 N N . HIS D 1 165 ? -31.858 47.035 -35.941 1.00 30.44 ? 146 HIS D N 1 ATOM 5934 C CA . HIS D 1 165 ? -33.195 46.607 -36.365 1.00 26.95 ? 146 HIS D CA 1 ATOM 5935 C C . HIS D 1 165 ? -33.512 46.999 -37.819 1.00 30.12 ? 146 HIS D C 1 ATOM 5936 O O . HIS D 1 165 ? -32.678 47.573 -38.509 1.00 34.34 ? 146 HIS D O 1 ATOM 5937 C CB . HIS D 1 165 ? -34.273 47.088 -35.392 1.00 33.30 ? 146 HIS D CB 1 ATOM 5938 C CG . HIS D 1 165 ? -34.358 48.581 -35.262 1.00 37.21 ? 146 HIS D CG 1 ATOM 5939 N ND1 . HIS D 1 165 ? -34.667 49.397 -36.328 1.00 40.34 ? 146 HIS D ND1 1 ATOM 5940 C CD2 . HIS D 1 165 ? -34.180 49.379 -34.196 1.00 41.67 ? 146 HIS D CD2 1 ATOM 5941 C CE1 . HIS D 1 165 ? -34.668 50.655 -35.914 1.00 45.84 ? 146 HIS D CE1 1 ATOM 5942 N NE2 . HIS D 1 165 ? -34.378 50.679 -34.634 1.00 47.77 ? 146 HIS D NE2 1 ATOM 5943 N N . SER D 1 166 ? -34.720 46.693 -38.278 1.00 34.66 ? 147 SER D N 1 ATOM 5944 C CA . SER D 1 166 ? -35.057 46.753 -39.706 1.00 33.05 ? 147 SER D CA 1 ATOM 5945 C C . SER D 1 166 ? -35.035 48.144 -40.339 1.00 35.27 ? 147 SER D C 1 ATOM 5946 O O . SER D 1 166 ? -34.977 48.263 -41.561 1.00 38.95 ? 147 SER D O 1 ATOM 5947 C CB . SER D 1 166 ? -36.430 46.133 -39.942 1.00 32.49 ? 147 SER D CB 1 ATOM 5948 O OG . SER D 1 166 ? -37.407 46.870 -39.237 1.00 35.15 ? 147 SER D OG 1 ATOM 5949 N N . ARG D 1 167 ? -35.105 49.191 -39.525 1.00 36.33 ? 148 ARG D N 1 ATOM 5950 C CA . ARG D 1 167 ? -35.094 50.550 -40.061 1.00 40.21 ? 148 ARG D CA 1 ATOM 5951 C C . ARG D 1 167 ? -33.672 51.097 -40.175 1.00 40.08 ? 148 ARG D C 1 ATOM 5952 O O . ARG D 1 167 ? -33.455 52.166 -40.749 1.00 41.90 ? 148 ARG D O 1 ATOM 5953 C CB . ARG D 1 167 ? -35.956 51.492 -39.204 1.00 55.18 ? 148 ARG D CB 1 ATOM 5954 C CG . ARG D 1 167 ? -37.462 51.208 -39.208 1.00 53.31 ? 148 ARG D CG 1 ATOM 5955 C CD . ARG D 1 167 ? -38.237 52.256 -38.389 1.00 73.62 ? 148 ARG D CD 1 ATOM 5956 N NE . ARG D 1 167 ? -37.377 53.026 -37.481 1.00 80.34 ? 148 ARG D NE 1 ATOM 5957 C CZ . ARG D 1 167 ? -37.669 53.308 -36.210 1.00 87.40 ? 148 ARG D CZ 1 ATOM 5958 N NH1 . ARG D 1 167 ? -38.809 52.882 -35.675 1.00 84.78 ? 148 ARG D NH1 1 ATOM 5959 N NH2 . ARG D 1 167 ? -36.815 54.016 -35.470 1.00 88.10 ? 148 ARG D NH2 1 ATOM 5960 N N . GLU D 1 168 ? -32.716 50.357 -39.617 1.00 38.94 ? 149 GLU D N 1 ATOM 5961 C CA . GLU D 1 168 ? -31.307 50.737 -39.659 1.00 35.54 ? 149 GLU D CA 1 ATOM 5962 C C . GLU D 1 168 ? -30.514 49.879 -40.655 1.00 31.10 ? 149 GLU D C 1 ATOM 5963 O O . GLU D 1 168 ? -29.728 50.404 -41.439 1.00 33.45 ? 149 GLU D O 1 ATOM 5964 C CB . GLU D 1 168 ? -30.687 50.670 -38.253 1.00 38.35 ? 149 GLU D CB 1 ATOM 5965 C CG . GLU D 1 168 ? -31.254 51.676 -37.257 1.00 40.61 ? 149 GLU D CG 1 ATOM 5966 C CD . GLU D 1 168 ? -30.720 51.502 -35.822 1.00 50.78 ? 149 GLU D CD 1 ATOM 5967 O OE1 . GLU D 1 168 ? -30.502 50.336 -35.382 1.00 39.25 ? 149 GLU D OE1 1 ATOM 5968 O OE2 . GLU D 1 168 ? -30.533 52.546 -35.136 1.00 62.94 ? 149 GLU D OE2 1 ATOM 5969 N N . ILE D 1 169 ? -30.719 48.564 -40.610 1.00 28.89 ? 150 ILE D N 1 ATOM 5970 C CA . ILE D 1 169 ? -30.125 47.645 -41.582 1.00 27.82 ? 150 ILE D CA 1 ATOM 5971 C C . ILE D 1 169 ? -31.199 46.715 -42.127 1.00 28.10 ? 150 ILE D C 1 ATOM 5972 O O . ILE D 1 169 ? -31.943 46.103 -41.353 1.00 29.00 ? 150 ILE D O 1 ATOM 5973 C CB . ILE D 1 169 ? -28.959 46.794 -40.970 1.00 24.20 ? 150 ILE D CB 1 ATOM 5974 C CG1 . ILE D 1 169 ? -27.735 47.680 -40.708 1.00 27.39 ? 150 ILE D CG1 1 ATOM 5975 C CG2 . ILE D 1 169 ? -28.582 45.613 -41.877 1.00 16.36 ? 150 ILE D CG2 1 ATOM 5976 C CD1 . ILE D 1 169 ? -26.534 46.941 -40.143 1.00 23.92 ? 150 ILE D CD1 1 ATOM 5977 N N . SER D 1 170 ? -31.297 46.624 -43.454 1.00 29.74 ? 151 SER D N 1 ATOM 5978 C CA . SER D 1 170 ? -32.094 45.568 -44.085 1.00 32.26 ? 151 SER D CA 1 ATOM 5979 C C . SER D 1 170 ? -31.184 44.592 -44.825 1.00 35.80 ? 151 SER D C 1 ATOM 5980 O O . SER D 1 170 ? -30.291 45.010 -45.566 1.00 43.15 ? 151 SER D O 1 ATOM 5981 C CB . SER D 1 170 ? -33.141 46.145 -45.038 1.00 34.53 ? 151 SER D CB 1 ATOM 5982 O OG . SER D 1 170 ? -32.536 46.733 -46.165 1.00 38.03 ? 151 SER D OG 1 ATOM 5983 N N . VAL D 1 171 ? -31.389 43.296 -44.610 1.00 40.25 ? 152 VAL D N 1 ATOM 5984 C CA . VAL D 1 171 ? -30.645 42.275 -45.355 1.00 41.67 ? 152 VAL D CA 1 ATOM 5985 C C . VAL D 1 171 ? -31.528 41.632 -46.413 1.00 40.65 ? 152 VAL D C 1 ATOM 5986 O O . VAL D 1 171 ? -32.698 41.350 -46.171 1.00 48.51 ? 152 VAL D O 1 ATOM 5987 C CB . VAL D 1 171 ? -30.107 41.175 -44.439 1.00 39.28 ? 152 VAL D CB 1 ATOM 5988 C CG1 . VAL D 1 171 ? -28.843 41.646 -43.739 1.00 44.17 ? 152 VAL D CG1 1 ATOM 5989 C CG2 . VAL D 1 171 ? -31.168 40.777 -43.430 1.00 34.89 ? 152 VAL D CG2 1 ATOM 5990 N N . ASP D 1 172 ? -30.962 41.405 -47.587 1.00 35.71 ? 153 ASP D N 1 ATOM 5991 C CA . ASP D 1 172 ? -31.709 40.844 -48.699 1.00 37.65 ? 153 ASP D CA 1 ATOM 5992 C C . ASP D 1 172 ? -30.822 39.874 -49.455 1.00 43.02 ? 153 ASP D C 1 ATOM 5993 O O . ASP D 1 172 ? -29.605 40.084 -49.555 1.00 37.43 ? 153 ASP D O 1 ATOM 5994 C CB . ASP D 1 172 ? -32.159 41.954 -49.635 1.00 37.76 ? 153 ASP D CB 1 ATOM 5995 C CG . ASP D 1 172 ? -32.582 43.214 -48.882 1.00 65.92 ? 153 ASP D CG 1 ATOM 5996 O OD1 . ASP D 1 172 ? -33.745 43.234 -48.401 1.00 75.96 ? 153 ASP D OD1 1 ATOM 5997 O OD2 . ASP D 1 172 ? -31.756 44.170 -48.761 1.00 59.99 ? 153 ASP D OD2 1 ATOM 5998 N N . PRO D 1 173 ? -31.417 38.787 -49.969 1.00 45.17 ? 154 PRO D N 1 ATOM 5999 C CA . PRO D 1 173 ? -30.681 37.827 -50.806 1.00 42.02 ? 154 PRO D CA 1 ATOM 6000 C C . PRO D 1 173 ? -30.337 38.475 -52.138 1.00 46.89 ? 154 PRO D C 1 ATOM 6001 O O . PRO D 1 173 ? -30.983 39.443 -52.545 1.00 48.01 ? 154 PRO D O 1 ATOM 6002 C CB . PRO D 1 173 ? -31.687 36.698 -51.025 1.00 36.25 ? 154 PRO D CB 1 ATOM 6003 C CG . PRO D 1 173 ? -32.726 36.880 -49.956 1.00 41.81 ? 154 PRO D CG 1 ATOM 6004 C CD . PRO D 1 173 ? -32.801 38.359 -49.717 1.00 39.53 ? 154 PRO D CD 1 ATOM 6005 N N . THR D 1 174 ? -29.352 37.964 -52.818 1.00 51.33 ? 155 THR D N 1 ATOM 6006 C CA . THR D 1 174 ? -28.948 38.545 -54.068 1.00 59.40 ? 155 THR D CA 1 ATOM 6007 C C . THR D 1 174 ? -29.911 38.207 -55.191 1.00 63.14 ? 155 THR D C 1 ATOM 6008 O O . THR D 1 174 ? -30.306 37.098 -55.360 1.00 69.07 ? 155 THR D O 1 ATOM 6009 C CB . THR D 1 174 ? -27.488 38.149 -54.341 1.00 64.34 ? 155 THR D CB 1 ATOM 6010 O OG1 . THR D 1 174 ? -26.639 39.103 -53.711 1.00 58.33 ? 155 THR D OG1 1 ATOM 6011 C CG2 . THR D 1 174 ? -27.143 38.105 -55.789 1.00 75.81 ? 155 THR D CG2 1 ATOM 6012 N N . THR D 1 175 ? -30.257 39.197 -55.981 1.00 74.57 ? 156 THR D N 1 ATOM 6013 C CA . THR D 1 175 ? -31.238 39.044 -57.033 1.00 80.66 ? 156 THR D CA 1 ATOM 6014 C C . THR D 1 175 ? -30.788 38.029 -58.064 1.00 82.51 ? 156 THR D C 1 ATOM 6015 O O . THR D 1 175 ? -31.575 37.276 -58.603 1.00 82.61 ? 156 THR D O 1 ATOM 6016 C CB . THR D 1 175 ? -31.501 40.383 -57.721 1.00 76.39 ? 156 THR D CB 1 ATOM 6017 O OG1 . THR D 1 175 ? -30.295 40.872 -58.297 1.00 63.89 ? 156 THR D OG1 1 ATOM 6018 C CG2 . THR D 1 175 ? -31.979 41.363 -56.724 1.00 64.59 ? 156 THR D CG2 1 ATOM 6019 N N . GLU D 1 176 ? -29.501 38.015 -58.312 1.00 81.75 ? 157 GLU D N 1 ATOM 6020 C CA . GLU D 1 176 ? -28.912 37.289 -59.393 1.00 80.33 ? 157 GLU D CA 1 ATOM 6021 C C . GLU D 1 176 ? -29.056 35.834 -59.117 1.00 83.47 ? 157 GLU D C 1 ATOM 6022 O O . GLU D 1 176 ? -29.500 35.439 -58.063 1.00 82.99 ? 157 GLU D O 1 ATOM 6023 C CB . GLU D 1 176 ? -27.441 37.613 -59.452 1.00 84.43 ? 157 GLU D CB 1 ATOM 6024 C CG . GLU D 1 176 ? -27.160 39.079 -59.223 1.00 86.51 ? 157 GLU D CG 1 ATOM 6025 C CD . GLU D 1 176 ? -25.905 39.302 -58.426 1.00 96.74 ? 157 GLU D CD 1 ATOM 6026 O OE1 . GLU D 1 176 ? -25.401 38.331 -57.835 1.00 93.19 ? 157 GLU D OE1 1 ATOM 6027 O OE2 . GLU D 1 176 ? -25.428 40.451 -58.396 1.00 96.84 ? 157 GLU D OE2 1 ATOM 6028 N N . ASN D 1 177 ? -28.760 35.036 -60.122 1.00 80.51 ? 158 ASN D N 1 ATOM 6029 C CA . ASN D 1 177 ? -29.013 33.624 -60.094 1.00 80.68 ? 158 ASN D CA 1 ATOM 6030 C C . ASN D 1 177 ? -27.750 32.796 -60.197 1.00 81.51 ? 158 ASN D C 1 ATOM 6031 O O . ASN D 1 177 ? -27.003 32.954 -61.155 1.00 82.05 ? 158 ASN D O 1 ATOM 6032 C CB . ASN D 1 177 ? -29.861 33.320 -61.306 1.00 79.63 ? 158 ASN D CB 1 ATOM 6033 C CG . ASN D 1 177 ? -29.335 33.995 -62.563 1.00 86.43 ? 158 ASN D CG 1 ATOM 6034 O OD1 . ASN D 1 177 ? -30.066 34.200 -63.528 1.00 81.64 ? 158 ASN D OD1 1 ATOM 6035 N ND2 . ASN D 1 177 ? -28.063 34.369 -62.535 1.00 71.24 ? 158 ASN D ND2 1 ATOM 6036 N N . SER D 1 178 ? -27.547 31.893 -59.236 1.00 62.97 ? 159 SER D N 1 ATOM 6037 C CA . SER D 1 178 ? -26.519 30.861 -59.273 1.00 67.55 ? 159 SER D CA 1 ATOM 6038 C C . SER D 1 178 ? -26.240 30.291 -57.891 1.00 66.42 ? 159 SER D C 1 ATOM 6039 O O . SER D 1 178 ? -25.271 29.564 -57.662 1.00 60.15 ? 159 SER D O 1 ATOM 6040 C CB . SER D 1 178 ? -25.225 31.349 -59.918 1.00 78.26 ? 159 SER D CB 1 ATOM 6041 O OG . SER D 1 178 ? -25.072 32.753 -59.857 1.00 71.93 ? 159 SER D OG 1 ATOM 6042 N N . ASP D 1 180 ? -24.025 28.007 -55.607 1.00 64.85 ? 161 ASP D N 1 ATOM 6043 C CA . ASP D 1 180 ? -24.294 26.576 -55.823 1.00 70.73 ? 161 ASP D CA 1 ATOM 6044 C C . ASP D 1 180 ? -22.991 25.843 -56.049 1.00 57.95 ? 161 ASP D C 1 ATOM 6045 O O . ASP D 1 180 ? -21.944 26.245 -55.532 1.00 56.73 ? 161 ASP D O 1 ATOM 6046 C CB . ASP D 1 180 ? -25.252 26.334 -57.010 1.00 70.12 ? 161 ASP D CB 1 ATOM 6047 C CG . ASP D 1 180 ? -26.744 26.357 -56.598 1.00 74.79 ? 161 ASP D CG 1 ATOM 6048 O OD1 . ASP D 1 180 ? -27.315 27.470 -56.430 1.00 70.60 ? 161 ASP D OD1 1 ATOM 6049 O OD2 . ASP D 1 180 ? -27.354 25.262 -56.470 1.00 65.11 ? 161 ASP D OD2 1 ATOM 6050 N N . SER D 1 181 ? -23.031 24.794 -56.861 1.00 53.31 ? 162 SER D N 1 ATOM 6051 C CA . SER D 1 181 ? -21.827 23.990 -57.028 1.00 63.31 ? 162 SER D CA 1 ATOM 6052 C C . SER D 1 181 ? -20.728 24.724 -57.802 1.00 66.83 ? 162 SER D C 1 ATOM 6053 O O . SER D 1 181 ? -19.677 24.135 -58.083 1.00 76.74 ? 162 SER D O 1 ATOM 6054 C CB . SER D 1 181 ? -22.133 22.635 -57.698 1.00 65.38 ? 162 SER D CB 1 ATOM 6055 O OG . SER D 1 181 ? -22.802 21.741 -56.816 1.00 64.40 ? 162 SER D OG 1 ATOM 6056 N N . GLU D 1 182 ? -20.961 25.994 -58.136 1.00 54.68 ? 163 GLU D N 1 ATOM 6057 C CA . GLU D 1 182 ? -20.082 26.707 -59.057 1.00 48.18 ? 163 GLU D CA 1 ATOM 6058 C C . GLU D 1 182 ? -18.640 26.736 -58.577 1.00 51.84 ? 163 GLU D C 1 ATOM 6059 O O . GLU D 1 182 ? -17.710 26.600 -59.374 1.00 55.47 ? 163 GLU D O 1 ATOM 6060 C CB . GLU D 1 182 ? -20.585 28.126 -59.304 1.00 50.16 ? 163 GLU D CB 1 ATOM 6061 C CG . GLU D 1 182 ? -19.843 28.824 -60.441 1.00 60.13 ? 163 GLU D CG 1 ATOM 6062 C CD . GLU D 1 182 ? -20.261 30.279 -60.635 1.00 67.50 ? 163 GLU D CD 1 ATOM 6063 O OE1 . GLU D 1 182 ? -21.182 30.752 -59.924 1.00 68.49 ? 163 GLU D OE1 1 ATOM 6064 O OE2 . GLU D 1 182 ? -19.659 30.947 -61.505 1.00 67.96 ? 163 GLU D OE2 1 ATOM 6065 N N . TYR D 1 183 ? -18.460 26.899 -57.270 1.00 47.66 ? 164 TYR D N 1 ATOM 6066 C CA . TYR D 1 183 ? -17.124 26.858 -56.694 1.00 46.11 ? 164 TYR D CA 1 ATOM 6067 C C . TYR D 1 183 ? -16.958 25.707 -55.704 1.00 46.80 ? 164 TYR D C 1 ATOM 6068 O O . TYR D 1 183 ? -15.970 25.662 -54.958 1.00 39.76 ? 164 TYR D O 1 ATOM 6069 C CB . TYR D 1 183 ? -16.807 28.169 -55.997 1.00 40.41 ? 164 TYR D CB 1 ATOM 6070 C CG . TYR D 1 183 ? -17.053 29.391 -56.840 1.00 51.06 ? 164 TYR D CG 1 ATOM 6071 C CD1 . TYR D 1 183 ? -16.319 29.621 -58.002 1.00 52.05 ? 164 TYR D CD1 1 ATOM 6072 C CD2 . TYR D 1 183 ? -18.002 30.333 -56.460 1.00 52.72 ? 164 TYR D CD2 1 ATOM 6073 C CE1 . TYR D 1 183 ? -16.528 30.752 -58.770 1.00 42.34 ? 164 TYR D CE1 1 ATOM 6074 C CE2 . TYR D 1 183 ? -18.230 31.464 -57.220 1.00 53.11 ? 164 TYR D CE2 1 ATOM 6075 C CZ . TYR D 1 183 ? -17.490 31.671 -58.375 1.00 51.06 ? 164 TYR D CZ 1 ATOM 6076 O OH . TYR D 1 183 ? -17.729 32.802 -59.131 1.00 56.25 ? 164 TYR D OH 1 ATOM 6077 N N . PHE D 1 184 ? -17.924 24.789 -55.696 1.00 42.51 ? 165 PHE D N 1 ATOM 6078 C CA . PHE D 1 184 ? -17.888 23.670 -54.760 1.00 39.03 ? 165 PHE D CA 1 ATOM 6079 C C . PHE D 1 184 ? -16.822 22.648 -55.131 1.00 35.08 ? 165 PHE D C 1 ATOM 6080 O O . PHE D 1 184 ? -16.630 22.340 -56.300 1.00 39.09 ? 165 PHE D O 1 ATOM 6081 C CB . PHE D 1 184 ? -19.239 22.980 -54.643 1.00 36.62 ? 165 PHE D CB 1 ATOM 6082 C CG . PHE D 1 184 ? -19.344 22.091 -53.444 1.00 30.55 ? 165 PHE D CG 1 ATOM 6083 C CD1 . PHE D 1 184 ? -19.367 22.633 -52.171 1.00 29.31 ? 165 PHE D CD1 1 ATOM 6084 C CD2 . PHE D 1 184 ? -19.419 20.715 -53.586 1.00 39.73 ? 165 PHE D CD2 1 ATOM 6085 C CE1 . PHE D 1 184 ? -19.465 21.815 -51.052 1.00 30.62 ? 165 PHE D CE1 1 ATOM 6086 C CE2 . PHE D 1 184 ? -19.522 19.880 -52.477 1.00 36.75 ? 165 PHE D CE2 1 ATOM 6087 C CZ . PHE D 1 184 ? -19.541 20.433 -51.204 1.00 33.17 ? 165 PHE D CZ 1 ATOM 6088 N N . SER D 1 185 ? -16.136 22.129 -54.118 1.00 31.52 ? 166 SER D N 1 ATOM 6089 C CA . SER D 1 185 ? -15.001 21.252 -54.327 1.00 29.60 ? 166 SER D CA 1 ATOM 6090 C C . SER D 1 185 ? -15.441 19.882 -54.846 1.00 37.73 ? 166 SER D C 1 ATOM 6091 O O . SER D 1 185 ? -16.310 19.225 -54.268 1.00 36.04 ? 166 SER D O 1 ATOM 6092 C CB . SER D 1 185 ? -14.200 21.106 -53.031 1.00 29.64 ? 166 SER D CB 1 ATOM 6093 O OG . SER D 1 185 ? -13.056 20.288 -53.218 1.00 33.48 ? 166 SER D OG 1 ATOM 6094 N N . GLN D 1 186 ? -14.827 19.454 -55.944 1.00 39.72 ? 167 GLN D N 1 ATOM 6095 C CA . GLN D 1 186 ? -15.071 18.125 -56.482 1.00 34.67 ? 167 GLN D CA 1 ATOM 6096 C C . GLN D 1 186 ? -14.535 17.047 -55.541 1.00 39.92 ? 167 GLN D C 1 ATOM 6097 O O . GLN D 1 186 ? -14.938 15.883 -55.633 1.00 39.66 ? 167 GLN D O 1 ATOM 6098 C CB . GLN D 1 186 ? -14.430 17.987 -57.864 1.00 37.85 ? 167 GLN D CB 1 ATOM 6099 C CG . GLN D 1 186 ? -13.078 18.684 -57.958 1.00 50.44 ? 167 GLN D CG 1 ATOM 6100 C CD . GLN D 1 186 ? -12.331 18.417 -59.264 1.00 52.64 ? 167 GLN D CD 1 ATOM 6101 O OE1 . GLN D 1 186 ? -12.451 17.343 -59.857 1.00 47.76 ? 167 GLN D OE1 1 ATOM 6102 N NE2 . GLN D 1 186 ? -11.538 19.400 -59.704 1.00 55.73 ? 167 GLN D NE2 1 ATOM 6103 N N . TYR D 1 187 ? -13.637 17.428 -54.630 1.00 37.59 ? 168 TYR D N 1 ATOM 6104 C CA . TYR D 1 187 ? -12.987 16.439 -53.766 1.00 32.55 ? 168 TYR D CA 1 ATOM 6105 C C . TYR D 1 187 ? -13.661 16.242 -52.414 1.00 30.78 ? 168 TYR D C 1 ATOM 6106 O O . TYR D 1 187 ? -13.264 15.369 -51.640 1.00 30.87 ? 168 TYR D O 1 ATOM 6107 C CB . TYR D 1 187 ? -11.492 16.728 -53.609 1.00 37.66 ? 168 TYR D CB 1 ATOM 6108 C CG . TYR D 1 187 ? -10.781 16.844 -54.937 1.00 38.74 ? 168 TYR D CG 1 ATOM 6109 C CD1 . TYR D 1 187 ? -10.680 15.752 -55.784 1.00 39.72 ? 168 TYR D CD1 1 ATOM 6110 C CD2 . TYR D 1 187 ? -10.226 18.046 -55.351 1.00 36.58 ? 168 TYR D CD2 1 ATOM 6111 C CE1 . TYR D 1 187 ? -10.045 15.846 -57.014 1.00 40.79 ? 168 TYR D CE1 1 ATOM 6112 C CE2 . TYR D 1 187 ? -9.583 18.147 -56.575 1.00 44.75 ? 168 TYR D CE2 1 ATOM 6113 C CZ . TYR D 1 187 ? -9.495 17.038 -57.402 1.00 41.58 ? 168 TYR D CZ 1 ATOM 6114 O OH . TYR D 1 187 ? -8.859 17.119 -58.619 1.00 50.15 ? 168 TYR D OH 1 ATOM 6115 N N . SER D 1 188 ? -14.688 17.037 -52.134 1.00 28.05 ? 169 SER D N 1 ATOM 6116 C CA . SER D 1 188 ? -15.518 16.792 -50.955 1.00 26.08 ? 169 SER D CA 1 ATOM 6117 C C . SER D 1 188 ? -16.147 15.391 -50.982 1.00 26.61 ? 169 SER D C 1 ATOM 6118 O O . SER D 1 188 ? -16.368 14.828 -52.059 1.00 31.60 ? 169 SER D O 1 ATOM 6119 C CB . SER D 1 188 ? -16.622 17.844 -50.875 1.00 27.30 ? 169 SER D CB 1 ATOM 6120 O OG . SER D 1 188 ? -17.357 17.713 -49.676 1.00 28.96 ? 169 SER D OG 1 ATOM 6121 N N . ARG D 1 189 ? -16.436 14.833 -49.805 1.00 28.22 ? 170 ARG D N 1 ATOM 6122 C CA . ARG D 1 189 ? -17.207 13.586 -49.708 1.00 25.64 ? 170 ARG D CA 1 ATOM 6123 C C . ARG D 1 189 ? -18.694 13.802 -50.001 1.00 29.84 ? 170 ARG D C 1 ATOM 6124 O O . ARG D 1 189 ? -19.470 12.841 -50.019 1.00 32.77 ? 170 ARG D O 1 ATOM 6125 C CB . ARG D 1 189 ? -17.066 12.941 -48.326 1.00 20.55 ? 170 ARG D CB 1 ATOM 6126 C CG . ARG D 1 189 ? -15.652 12.537 -47.973 1.00 35.00 ? 170 ARG D CG 1 ATOM 6127 C CD . ARG D 1 189 ? -15.620 11.180 -47.286 1.00 48.72 ? 170 ARG D CD 1 ATOM 6128 N NE . ARG D 1 189 ? -16.320 11.168 -45.998 1.00 55.07 ? 170 ARG D NE 1 ATOM 6129 C CZ . ARG D 1 189 ? -16.819 10.076 -45.414 1.00 55.49 ? 170 ARG D CZ 1 ATOM 6130 N NH1 . ARG D 1 189 ? -16.715 8.885 -46.003 1.00 51.78 ? 170 ARG D NH1 1 ATOM 6131 N NH2 . ARG D 1 189 ? -17.432 10.179 -44.239 1.00 58.62 ? 170 ARG D NH2 1 ATOM 6132 N N . PHE D 1 190 ? -19.089 15.058 -50.206 1.00 25.34 ? 171 PHE D N 1 ATOM 6133 C CA . PHE D 1 190 ? -20.500 15.398 -50.351 1.00 26.10 ? 171 PHE D CA 1 ATOM 6134 C C . PHE D 1 190 ? -20.753 16.171 -51.635 1.00 29.59 ? 171 PHE D C 1 ATOM 6135 O O . PHE D 1 190 ? -19.810 16.655 -52.277 1.00 34.23 ? 171 PHE D O 1 ATOM 6136 C CB . PHE D 1 190 ? -20.987 16.217 -49.154 1.00 24.54 ? 171 PHE D CB 1 ATOM 6137 C CG . PHE D 1 190 ? -20.719 15.567 -47.825 1.00 24.52 ? 171 PHE D CG 1 ATOM 6138 C CD1 . PHE D 1 190 ? -19.464 15.642 -47.240 1.00 26.49 ? 171 PHE D CD1 1 ATOM 6139 C CD2 . PHE D 1 190 ? -21.719 14.880 -47.154 1.00 29.58 ? 171 PHE D CD2 1 ATOM 6140 C CE1 . PHE D 1 190 ? -19.207 15.031 -46.012 1.00 23.64 ? 171 PHE D CE1 1 ATOM 6141 C CE2 . PHE D 1 190 ? -21.468 14.268 -45.927 1.00 27.70 ? 171 PHE D CE2 1 ATOM 6142 C CZ . PHE D 1 190 ? -20.209 14.350 -45.362 1.00 23.80 ? 171 PHE D CZ 1 ATOM 6143 N N . GLU D 1 191 ? -22.027 16.284 -52.005 1.00 27.62 ? 172 GLU D N 1 ATOM 6144 C CA . GLU D 1 191 ? -22.419 17.030 -53.197 1.00 35.13 ? 172 GLU D CA 1 ATOM 6145 C C . GLU D 1 191 ? -23.664 17.883 -52.934 1.00 36.38 ? 172 GLU D C 1 ATOM 6146 O O . GLU D 1 191 ? -24.504 17.534 -52.099 1.00 36.42 ? 172 GLU D O 1 ATOM 6147 C CB . GLU D 1 191 ? -22.605 16.109 -54.418 1.00 32.97 ? 172 GLU D CB 1 ATOM 6148 C CG . GLU D 1 191 ? -23.700 15.054 -54.304 1.00 41.48 ? 172 GLU D CG 1 ATOM 6149 C CD . GLU D 1 191 ? -23.668 14.055 -55.479 1.00 64.56 ? 172 GLU D CD 1 ATOM 6150 O OE1 . GLU D 1 191 ? -22.979 14.351 -56.487 1.00 65.54 ? 172 GLU D OE1 1 ATOM 6151 O OE2 . GLU D 1 191 ? -24.317 12.976 -55.392 1.00 61.11 ? 172 GLU D OE2 1 ATOM 6152 N N . ILE D 1 192 ? -23.769 19.010 -53.631 1.00 35.07 ? 173 ILE D N 1 ATOM 6153 C CA . ILE D 1 192 ? -24.887 19.914 -53.409 1.00 38.17 ? 173 ILE D CA 1 ATOM 6154 C C . ILE D 1 192 ? -25.994 19.629 -54.409 1.00 41.87 ? 173 ILE D C 1 ATOM 6155 O O . ILE D 1 192 ? -25.745 19.554 -55.612 1.00 45.34 ? 173 ILE D O 1 ATOM 6156 C CB . ILE D 1 192 ? -24.455 21.392 -53.476 1.00 42.01 ? 173 ILE D CB 1 ATOM 6157 C CG1 . ILE D 1 192 ? -23.436 21.687 -52.370 1.00 33.45 ? 173 ILE D CG1 1 ATOM 6158 C CG2 . ILE D 1 192 ? -25.666 22.323 -53.354 1.00 38.37 ? 173 ILE D CG2 1 ATOM 6159 C CD1 . ILE D 1 192 ? -22.883 23.089 -52.434 1.00 43.29 ? 173 ILE D CD1 1 ATOM 6160 N N . LEU D 1 193 ? -27.211 19.460 -53.894 1.00 46.02 ? 174 LEU D N 1 ATOM 6161 C CA . LEU D 1 193 ? -28.390 19.171 -54.714 1.00 46.91 ? 174 LEU D CA 1 ATOM 6162 C C . LEU D 1 193 ? -29.113 20.463 -55.066 1.00 48.14 ? 174 LEU D C 1 ATOM 6163 O O . LEU D 1 193 ? -29.558 20.649 -56.199 1.00 59.16 ? 174 LEU D O 1 ATOM 6164 C CB . LEU D 1 193 ? -29.339 18.202 -53.989 1.00 37.42 ? 174 LEU D CB 1 ATOM 6165 C CG . LEU D 1 193 ? -28.644 16.911 -53.543 1.00 42.76 ? 174 LEU D CG 1 ATOM 6166 C CD1 . LEU D 1 193 ? -29.583 15.976 -52.796 1.00 36.08 ? 174 LEU D CD1 1 ATOM 6167 C CD2 . LEU D 1 193 ? -27.967 16.202 -54.734 1.00 42.00 ? 174 LEU D CD2 1 ATOM 6168 N N . ASP D 1 194 ? -29.214 21.359 -54.091 1.00 46.45 ? 175 ASP D N 1 ATOM 6169 C CA . ASP D 1 194 ? -29.857 22.650 -54.306 1.00 50.34 ? 175 ASP D CA 1 ATOM 6170 C C . ASP D 1 194 ? -29.566 23.680 -53.194 1.00 49.58 ? 175 ASP D C 1 ATOM 6171 O O . ASP D 1 194 ? -29.333 23.325 -52.029 1.00 42.20 ? 175 ASP D O 1 ATOM 6172 C CB . ASP D 1 194 ? -31.371 22.467 -54.474 1.00 50.56 ? 175 ASP D CB 1 ATOM 6173 C CG . ASP D 1 194 ? -32.023 23.648 -55.184 1.00 70.83 ? 175 ASP D CG 1 ATOM 6174 O OD1 . ASP D 1 194 ? -31.382 24.207 -56.103 1.00 76.88 ? 175 ASP D OD1 1 ATOM 6175 O OD2 . ASP D 1 194 ? -33.164 24.026 -54.822 1.00 67.13 ? 175 ASP D OD2 1 ATOM 6176 N N . VAL D 1 195 ? -29.574 24.960 -53.568 1.00 52.33 ? 176 VAL D N 1 ATOM 6177 C CA . VAL D 1 195 ? -29.462 26.045 -52.595 1.00 48.44 ? 176 VAL D CA 1 ATOM 6178 C C . VAL D 1 195 ? -30.576 27.073 -52.789 1.00 41.93 ? 176 VAL D C 1 ATOM 6179 O O . VAL D 1 195 ? -30.676 27.674 -53.849 1.00 50.82 ? 176 VAL D O 1 ATOM 6180 C CB . VAL D 1 195 ? -28.105 26.773 -52.686 1.00 40.94 ? 176 VAL D CB 1 ATOM 6181 C CG1 . VAL D 1 195 ? -28.064 27.916 -51.697 1.00 34.83 ? 176 VAL D CG1 1 ATOM 6182 C CG2 . VAL D 1 195 ? -26.949 25.814 -52.425 1.00 43.56 ? 176 VAL D CG2 1 ATOM 6183 N N . THR D 1 196 ? -31.405 27.268 -51.767 1.00 33.79 ? 177 THR D N 1 ATOM 6184 C CA . THR D 1 196 ? -32.443 28.298 -51.800 1.00 39.48 ? 177 THR D CA 1 ATOM 6185 C C . THR D 1 196 ? -32.259 29.358 -50.699 1.00 43.69 ? 177 THR D C 1 ATOM 6186 O O . THR D 1 196 ? -31.702 29.086 -49.637 1.00 44.61 ? 177 THR D O 1 ATOM 6187 C CB . THR D 1 196 ? -33.858 27.696 -51.698 1.00 43.99 ? 177 THR D CB 1 ATOM 6188 O OG1 . THR D 1 196 ? -34.011 27.023 -50.440 1.00 48.53 ? 177 THR D OG1 1 ATOM 6189 C CG2 . THR D 1 196 ? -34.097 26.713 -52.828 1.00 46.39 ? 177 THR D CG2 1 ATOM 6190 N N . GLN D 1 197 ? -32.744 30.564 -50.965 1.00 47.15 ? 178 GLN D N 1 ATOM 6191 C CA . GLN D 1 197 ? -32.596 31.683 -50.051 1.00 37.93 ? 178 GLN D CA 1 ATOM 6192 C C . GLN D 1 197 ? -33.979 32.269 -49.759 1.00 41.00 ? 178 GLN D C 1 ATOM 6193 O O . GLN D 1 197 ? -34.810 32.381 -50.662 1.00 47.56 ? 178 GLN D O 1 ATOM 6194 C CB . GLN D 1 197 ? -31.695 32.750 -50.694 1.00 38.14 ? 178 GLN D CB 1 ATOM 6195 C CG . GLN D 1 197 ? -30.305 32.246 -51.148 1.00 53.38 ? 178 GLN D CG 1 ATOM 6196 C CD . GLN D 1 197 ? -29.200 33.356 -51.178 1.00 77.19 ? 178 GLN D CD 1 ATOM 6197 O OE1 . GLN D 1 197 ? -29.480 34.529 -51.471 1.00 72.82 ? 178 GLN D OE1 1 ATOM 6198 N NE2 . GLN D 1 197 ? -27.941 32.970 -50.866 1.00 48.91 ? 178 GLN D NE2 1 ATOM 6199 N N . LYS D 1 198 ? -34.254 32.634 -48.514 1.00 38.71 ? 179 LYS D N 1 ATOM 6200 C CA . LYS D 1 198 ? -35.435 33.469 -48.267 1.00 48.80 ? 179 LYS D CA 1 ATOM 6201 C C . LYS D 1 198 ? -35.213 34.485 -47.148 1.00 43.68 ? 179 LYS D C 1 ATOM 6202 O O . LYS D 1 198 ? -34.345 34.309 -46.299 1.00 49.22 ? 179 LYS D O 1 ATOM 6203 C CB . LYS D 1 198 ? -36.677 32.627 -47.994 1.00 42.47 ? 179 LYS D CB 1 ATOM 6204 C CG . LYS D 1 198 ? -36.883 32.320 -46.541 1.00 49.72 ? 179 LYS D CG 1 ATOM 6205 C CD . LYS D 1 198 ? -38.210 31.598 -46.321 1.00 66.21 ? 179 LYS D CD 1 ATOM 6206 C CE . LYS D 1 198 ? -38.307 31.064 -44.890 1.00 79.23 ? 179 LYS D CE 1 ATOM 6207 N NZ . LYS D 1 198 ? -39.620 30.408 -44.625 1.00 83.53 ? 179 LYS D NZ 1 ATOM 6208 N N . LYS D 1 199 ? -35.999 35.550 -47.147 1.00 43.17 ? 180 LYS D N 1 ATOM 6209 C CA . LYS D 1 199 ? -35.829 36.608 -46.160 1.00 38.42 ? 180 LYS D CA 1 ATOM 6210 C C . LYS D 1 199 ? -36.889 36.545 -45.040 1.00 42.40 ? 180 LYS D C 1 ATOM 6211 O O . LYS D 1 199 ? -38.077 36.355 -45.306 1.00 36.54 ? 180 LYS D O 1 ATOM 6212 C CB . LYS D 1 199 ? -35.856 37.960 -46.859 1.00 28.06 ? 180 LYS D CB 1 ATOM 6213 C CG . LYS D 1 199 ? -36.045 39.104 -45.922 1.00 48.59 ? 180 LYS D CG 1 ATOM 6214 C CD . LYS D 1 199 ? -36.080 40.406 -46.675 1.00 55.78 ? 180 LYS D CD 1 ATOM 6215 C CE . LYS D 1 199 ? -36.381 41.553 -45.718 1.00 61.20 ? 180 LYS D CE 1 ATOM 6216 N NZ . LYS D 1 199 ? -36.246 42.888 -46.388 1.00 70.52 ? 180 LYS D NZ 1 ATOM 6217 N N . ASN D 1 200 ? -36.453 36.688 -43.787 1.00 45.15 ? 181 ASN D N 1 ATOM 6218 C CA . ASN D 1 200 ? -37.374 36.733 -42.648 1.00 37.65 ? 181 ASN D CA 1 ATOM 6219 C C . ASN D 1 200 ? -37.292 38.060 -41.895 1.00 39.99 ? 181 ASN D C 1 ATOM 6220 O O . ASN D 1 200 ? -36.266 38.750 -41.905 1.00 35.63 ? 181 ASN D O 1 ATOM 6221 C CB . ASN D 1 200 ? -37.117 35.593 -41.661 1.00 38.24 ? 181 ASN D CB 1 ATOM 6222 C CG . ASN D 1 200 ? -37.040 34.249 -42.332 1.00 52.93 ? 181 ASN D CG 1 ATOM 6223 O OD1 . ASN D 1 200 ? -38.062 33.697 -42.733 1.00 58.44 ? 181 ASN D OD1 1 ATOM 6224 N ND2 . ASN D 1 200 ? -35.821 33.700 -42.453 1.00 56.25 ? 181 ASN D ND2 1 ATOM 6225 N N . SER D 1 201 ? -38.392 38.401 -41.237 1.00 46.07 ? 182 SER D N 1 ATOM 6226 C CA . SER D 1 201 ? -38.462 39.580 -40.395 1.00 35.96 ? 182 SER D CA 1 ATOM 6227 C C . SER D 1 201 ? -39.039 39.142 -39.053 1.00 31.29 ? 182 SER D C 1 ATOM 6228 O O . SER D 1 201 ? -40.199 38.770 -38.979 1.00 34.89 ? 182 SER D O 1 ATOM 6229 C CB . SER D 1 201 ? -39.348 40.631 -41.056 1.00 35.54 ? 182 SER D CB 1 ATOM 6230 O OG . SER D 1 201 ? -39.193 41.890 -40.423 1.00 54.46 ? 182 SER D OG 1 ATOM 6231 N N . VAL D 1 202 ? -38.220 39.175 -38.005 1.00 36.02 ? 183 VAL D N 1 ATOM 6232 C CA . VAL D 1 202 ? -38.542 38.543 -36.718 1.00 30.79 ? 183 VAL D CA 1 ATOM 6233 C C . VAL D 1 202 ? -38.616 39.563 -35.594 1.00 32.91 ? 183 VAL D C 1 ATOM 6234 O O . VAL D 1 202 ? -37.798 40.497 -35.535 1.00 37.36 ? 183 VAL D O 1 ATOM 6235 C CB . VAL D 1 202 ? -37.443 37.524 -36.346 1.00 31.57 ? 183 VAL D CB 1 ATOM 6236 C CG1 . VAL D 1 202 ? -37.703 36.919 -34.984 1.00 31.27 ? 183 VAL D CG1 1 ATOM 6237 C CG2 . VAL D 1 202 ? -37.308 36.460 -37.429 1.00 29.12 ? 183 VAL D CG2 1 ATOM 6238 N N . THR D 1 203 ? -39.590 39.398 -34.701 1.00 32.58 ? 184 THR D N 1 ATOM 6239 C CA . THR D 1 203 ? -39.643 40.240 -33.506 1.00 34.64 ? 184 THR D CA 1 ATOM 6240 C C . THR D 1 203 ? -39.238 39.442 -32.278 1.00 33.43 ? 184 THR D C 1 ATOM 6241 O O . THR D 1 203 ? -39.848 38.438 -31.969 1.00 38.33 ? 184 THR D O 1 ATOM 6242 C CB . THR D 1 203 ? -41.025 40.900 -33.298 1.00 36.98 ? 184 THR D CB 1 ATOM 6243 O OG1 . THR D 1 203 ? -41.240 41.888 -34.320 1.00 48.46 ? 184 THR D OG1 1 ATOM 6244 C CG2 . THR D 1 203 ? -41.082 41.592 -31.947 1.00 46.62 ? 184 THR D CG2 1 ATOM 6245 N N . TYR D 1 204 ? -38.196 39.891 -31.583 1.00 45.54 ? 185 TYR D N 1 ATOM 6246 C CA . TYR D 1 204 ? -37.720 39.208 -30.379 1.00 42.76 ? 185 TYR D CA 1 ATOM 6247 C C . TYR D 1 204 ? -38.357 39.748 -29.097 1.00 42.29 ? 185 TYR D C 1 ATOM 6248 O O . TYR D 1 204 ? -38.900 40.858 -29.070 1.00 40.42 ? 185 TYR D O 1 ATOM 6249 C CB . TYR D 1 204 ? -36.190 39.273 -30.291 1.00 36.77 ? 185 TYR D CB 1 ATOM 6250 C CG . TYR D 1 204 ? -35.502 38.564 -31.441 1.00 37.14 ? 185 TYR D CG 1 ATOM 6251 C CD1 . TYR D 1 204 ? -35.220 39.237 -32.624 1.00 35.21 ? 185 TYR D CD1 1 ATOM 6252 C CD2 . TYR D 1 204 ? -35.146 37.219 -31.350 1.00 36.38 ? 185 TYR D CD2 1 ATOM 6253 C CE1 . TYR D 1 204 ? -34.603 38.598 -33.688 1.00 29.58 ? 185 TYR D CE1 1 ATOM 6254 C CE2 . TYR D 1 204 ? -34.517 36.566 -32.408 1.00 30.06 ? 185 TYR D CE2 1 ATOM 6255 C CZ . TYR D 1 204 ? -34.253 37.265 -33.581 1.00 30.51 ? 185 TYR D CZ 1 ATOM 6256 O OH . TYR D 1 204 ? -33.644 36.646 -34.658 1.00 33.03 ? 185 TYR D OH 1 ATOM 6257 N N . SER D 1 205 ? -38.271 38.949 -28.036 1.00 47.10 ? 186 SER D N 1 ATOM 6258 C CA . SER D 1 205 ? -38.937 39.249 -26.772 1.00 49.88 ? 186 SER D CA 1 ATOM 6259 C C . SER D 1 205 ? -38.383 40.481 -26.087 1.00 48.18 ? 186 SER D C 1 ATOM 6260 O O . SER D 1 205 ? -39.023 41.060 -25.215 1.00 57.99 ? 186 SER D O 1 ATOM 6261 C CB . SER D 1 205 ? -38.867 38.045 -25.832 1.00 55.77 ? 186 SER D CB 1 ATOM 6262 O OG . SER D 1 205 ? -39.599 36.956 -26.365 1.00 65.53 ? 186 SER D OG 1 ATOM 6263 N N . CYS D 1 206 ? -37.193 40.891 -26.492 1.00 54.98 ? 187 CYS D N 1 ATOM 6264 C CA . CYS D 1 206 ? -36.534 42.025 -25.863 1.00 55.93 ? 187 CYS D CA 1 ATOM 6265 C C . CYS D 1 206 ? -37.053 43.403 -26.327 1.00 61.47 ? 187 CYS D C 1 ATOM 6266 O O . CYS D 1 206 ? -37.217 44.299 -25.508 1.00 70.80 ? 187 CYS D O 1 ATOM 6267 C CB . CYS D 1 206 ? -35.026 41.932 -26.090 1.00 55.92 ? 187 CYS D CB 1 ATOM 6268 S SG . CYS D 1 206 ? -34.488 42.541 -27.724 1.00 59.13 ? 187 CYS D SG 1 ATOM 6269 N N . CYS D 1 207 ? -37.317 43.567 -27.627 1.00 64.68 ? 188 CYS D N 1 ATOM 6270 C CA . CYS D 1 207 ? -37.592 44.888 -28.227 1.00 61.36 ? 188 CYS D CA 1 ATOM 6271 C C . CYS D 1 207 ? -38.814 44.870 -29.158 1.00 67.63 ? 188 CYS D C 1 ATOM 6272 O O . CYS D 1 207 ? -39.185 43.810 -29.686 1.00 67.34 ? 188 CYS D O 1 ATOM 6273 C CB . CYS D 1 207 ? -36.355 45.360 -29.001 1.00 62.85 ? 188 CYS D CB 1 ATOM 6274 S SG . CYS D 1 207 ? -34.888 44.304 -28.691 1.00 90.74 ? 188 CYS D SG 1 ATOM 6275 N N . PRO D 1 208 ? -39.444 46.045 -29.367 1.00 67.17 ? 189 PRO D N 1 ATOM 6276 C CA . PRO D 1 208 ? -40.652 46.161 -30.206 1.00 66.56 ? 189 PRO D CA 1 ATOM 6277 C C . PRO D 1 208 ? -40.336 46.296 -31.687 1.00 68.84 ? 189 PRO D C 1 ATOM 6278 O O . PRO D 1 208 ? -41.251 46.367 -32.512 1.00 77.48 ? 189 PRO D O 1 ATOM 6279 C CB . PRO D 1 208 ? -41.282 47.467 -29.721 1.00 65.40 ? 189 PRO D CB 1 ATOM 6280 C CG . PRO D 1 208 ? -40.096 48.288 -29.314 1.00 63.02 ? 189 PRO D CG 1 ATOM 6281 C CD . PRO D 1 208 ? -39.109 47.321 -28.705 1.00 53.82 ? 189 PRO D CD 1 ATOM 6282 N N . GLU D 1 209 ? -39.048 46.350 -32.008 1.00 71.48 ? 190 GLU D N 1 ATOM 6283 C CA . GLU D 1 209 ? -38.579 46.519 -33.383 1.00 61.73 ? 190 GLU D CA 1 ATOM 6284 C C . GLU D 1 209 ? -38.351 45.158 -34.061 1.00 49.50 ? 190 GLU D C 1 ATOM 6285 O O . GLU D 1 209 ? -38.154 44.145 -33.382 1.00 45.82 ? 190 GLU D O 1 ATOM 6286 C CB . GLU D 1 209 ? -37.270 47.310 -33.361 1.00 62.82 ? 190 GLU D CB 1 ATOM 6287 C CG . GLU D 1 209 ? -37.273 48.506 -32.409 1.00 59.74 ? 190 GLU D CG 1 ATOM 6288 C CD . GLU D 1 209 ? -37.983 49.717 -33.008 1.00 77.57 ? 190 GLU D CD 1 ATOM 6289 O OE1 . GLU D 1 209 ? -38.536 49.589 -34.127 1.00 83.95 ? 190 GLU D OE1 1 ATOM 6290 O OE2 . GLU D 1 209 ? -37.984 50.799 -32.375 1.00 73.24 ? 190 GLU D OE2 1 ATOM 6291 N N . ALA D 1 210 ? -38.375 45.131 -35.394 1.00 46.87 ? 191 ALA D N 1 ATOM 6292 C CA . ALA D 1 210 ? -38.166 43.881 -36.126 1.00 40.28 ? 191 ALA D CA 1 ATOM 6293 C C . ALA D 1 210 ? -36.725 43.798 -36.570 1.00 37.94 ? 191 ALA D C 1 ATOM 6294 O O . ALA D 1 210 ? -36.112 44.816 -36.898 1.00 31.81 ? 191 ALA D O 1 ATOM 6295 C CB . ALA D 1 210 ? -39.069 43.784 -37.327 1.00 37.27 ? 191 ALA D CB 1 ATOM 6296 N N . TYR D 1 211 ? -36.190 42.579 -36.593 1.00 36.43 ? 192 TYR D N 1 ATOM 6297 C CA . TYR D 1 211 ? -34.827 42.348 -37.065 1.00 31.55 ? 192 TYR D CA 1 ATOM 6298 C C . TYR D 1 211 ? -34.851 41.463 -38.289 1.00 31.60 ? 192 TYR D C 1 ATOM 6299 O O . TYR D 1 211 ? -35.348 40.336 -38.224 1.00 37.11 ? 192 TYR D O 1 ATOM 6300 C CB . TYR D 1 211 ? -33.979 41.709 -35.958 1.00 30.46 ? 192 TYR D CB 1 ATOM 6301 C CG . TYR D 1 211 ? -33.667 42.666 -34.838 1.00 31.01 ? 192 TYR D CG 1 ATOM 6302 C CD1 . TYR D 1 211 ? -34.614 42.963 -33.875 1.00 37.54 ? 192 TYR D CD1 1 ATOM 6303 C CD2 . TYR D 1 211 ? -32.432 43.298 -34.761 1.00 31.43 ? 192 TYR D CD2 1 ATOM 6304 C CE1 . TYR D 1 211 ? -34.342 43.864 -32.853 1.00 40.56 ? 192 TYR D CE1 1 ATOM 6305 C CE2 . TYR D 1 211 ? -32.143 44.197 -33.743 1.00 32.69 ? 192 TYR D CE2 1 ATOM 6306 C CZ . TYR D 1 211 ? -33.102 44.480 -32.791 1.00 38.10 ? 192 TYR D CZ 1 ATOM 6307 O OH . TYR D 1 211 ? -32.815 45.377 -31.773 1.00 44.52 ? 192 TYR D OH 1 ATOM 6308 N N . GLU D 1 212 ? -34.321 41.961 -39.405 1.00 31.56 ? 193 GLU D N 1 ATOM 6309 C CA . GLU D 1 212 ? -34.250 41.149 -40.632 1.00 32.19 ? 193 GLU D CA 1 ATOM 6310 C C . GLU D 1 212 ? -33.108 40.136 -40.629 1.00 25.55 ? 193 GLU D C 1 ATOM 6311 O O . GLU D 1 212 ? -32.030 40.396 -40.087 1.00 26.36 ? 193 GLU D O 1 ATOM 6312 C CB . GLU D 1 212 ? -34.152 42.044 -41.868 1.00 30.36 ? 193 GLU D CB 1 ATOM 6313 C CG . GLU D 1 212 ? -35.279 43.053 -41.972 1.00 37.28 ? 193 GLU D CG 1 ATOM 6314 C CD . GLU D 1 212 ? -35.301 43.776 -43.303 1.00 48.26 ? 193 GLU D CD 1 ATOM 6315 O OE1 . GLU D 1 212 ? -34.416 43.488 -44.147 1.00 48.38 ? 193 GLU D OE1 1 ATOM 6316 O OE2 . GLU D 1 212 ? -36.210 44.626 -43.504 1.00 57.97 ? 193 GLU D OE2 1 ATOM 6317 N N . ASP D 1 213 ? -33.363 38.983 -41.236 1.00 27.80 ? 194 ASP D N 1 ATOM 6318 C CA . ASP D 1 213 ? -32.310 38.003 -41.530 1.00 30.98 ? 194 ASP D CA 1 ATOM 6319 C C . ASP D 1 213 ? -32.555 37.285 -42.846 1.00 28.61 ? 194 ASP D C 1 ATOM 6320 O O . ASP D 1 213 ? -33.646 37.337 -43.409 1.00 29.93 ? 194 ASP D O 1 ATOM 6321 C CB . ASP D 1 213 ? -32.177 36.962 -40.421 1.00 32.11 ? 194 ASP D CB 1 ATOM 6322 C CG . ASP D 1 213 ? -33.499 36.268 -40.113 1.00 48.15 ? 194 ASP D CG 1 ATOM 6323 O OD1 . ASP D 1 213 ? -33.830 35.276 -40.811 1.00 47.33 ? 194 ASP D OD1 1 ATOM 6324 O OD2 . ASP D 1 213 ? -34.207 36.722 -39.170 1.00 59.31 ? 194 ASP D OD2 1 ATOM 6325 N N . VAL D 1 214 ? -31.519 36.621 -43.331 1.00 24.83 ? 195 VAL D N 1 ATOM 6326 C CA . VAL D 1 214 ? -31.649 35.761 -44.488 1.00 23.49 ? 195 VAL D CA 1 ATOM 6327 C C . VAL D 1 214 ? -31.444 34.326 -44.034 1.00 27.41 ? 195 VAL D C 1 ATOM 6328 O O . VAL D 1 214 ? -30.572 34.031 -43.206 1.00 25.61 ? 195 VAL D O 1 ATOM 6329 C CB . VAL D 1 214 ? -30.662 36.146 -45.591 1.00 21.93 ? 195 VAL D CB 1 ATOM 6330 C CG1 . VAL D 1 214 ? -30.677 35.127 -46.710 1.00 21.86 ? 195 VAL D CG1 1 ATOM 6331 C CG2 . VAL D 1 214 ? -31.001 37.530 -46.121 1.00 36.13 ? 195 VAL D CG2 1 ATOM 6332 N N . GLU D 1 215 ? -32.298 33.445 -44.545 1.00 34.80 ? 196 GLU D N 1 ATOM 6333 C CA . GLU D 1 215 ? -32.219 32.015 -44.274 1.00 33.60 ? 196 GLU D CA 1 ATOM 6334 C C . GLU D 1 215 ? -31.777 31.290 -45.542 1.00 32.72 ? 196 GLU D C 1 ATOM 6335 O O . GLU D 1 215 ? -32.446 31.379 -46.580 1.00 34.81 ? 196 GLU D O 1 ATOM 6336 C CB . GLU D 1 215 ? -33.582 31.508 -43.837 1.00 31.70 ? 196 GLU D CB 1 ATOM 6337 C CG . GLU D 1 215 ? -33.560 30.688 -42.570 1.00 48.72 ? 196 GLU D CG 1 ATOM 6338 C CD . GLU D 1 215 ? -34.952 30.210 -42.141 1.00 77.66 ? 196 GLU D CD 1 ATOM 6339 O OE1 . GLU D 1 215 ? -35.717 29.694 -43.003 1.00 78.86 ? 196 GLU D OE1 1 ATOM 6340 O OE2 . GLU D 1 215 ? -35.275 30.362 -40.935 1.00 74.84 ? 196 GLU D OE2 1 ATOM 6341 N N . VAL D 1 216 ? -30.647 30.588 -45.472 1.00 31.19 ? 197 VAL D N 1 ATOM 6342 C CA . VAL D 1 216 ? -30.099 29.913 -46.652 1.00 30.21 ? 197 VAL D CA 1 ATOM 6343 C C . VAL D 1 216 ? -30.243 28.417 -46.485 1.00 30.90 ? 197 VAL D C 1 ATOM 6344 O O . VAL D 1 216 ? -29.656 27.844 -45.576 1.00 42.09 ? 197 VAL D O 1 ATOM 6345 C CB . VAL D 1 216 ? -28.606 30.268 -46.899 1.00 28.09 ? 197 VAL D CB 1 ATOM 6346 C CG1 . VAL D 1 216 ? -28.061 29.458 -48.056 1.00 31.33 ? 197 VAL D CG1 1 ATOM 6347 C CG2 . VAL D 1 216 ? -28.442 31.753 -47.185 1.00 29.77 ? 197 VAL D CG2 1 ATOM 6348 N N . SER D 1 217 ? -31.027 27.786 -47.353 1.00 31.66 ? 198 SER D N 1 ATOM 6349 C CA . SER D 1 217 ? -31.266 26.345 -47.256 1.00 36.46 ? 198 SER D CA 1 ATOM 6350 C C . SER D 1 217 ? -30.349 25.539 -48.166 1.00 36.32 ? 198 SER D C 1 ATOM 6351 O O . SER D 1 217 ? -30.375 25.689 -49.386 1.00 34.17 ? 198 SER D O 1 ATOM 6352 C CB . SER D 1 217 ? -32.717 26.025 -47.584 1.00 42.41 ? 198 SER D CB 1 ATOM 6353 O OG . SER D 1 217 ? -33.578 26.776 -46.754 1.00 46.84 ? 198 SER D OG 1 ATOM 6354 N N . LEU D 1 218 ? -29.547 24.674 -47.558 1.00 35.11 ? 199 LEU D N 1 ATOM 6355 C CA . LEU D 1 218 ? -28.549 23.920 -48.294 1.00 34.13 ? 199 LEU D CA 1 ATOM 6356 C C . LEU D 1 218 ? -28.932 22.453 -48.347 1.00 41.68 ? 199 LEU D C 1 ATOM 6357 O O . LEU D 1 218 ? -28.870 21.750 -47.337 1.00 38.88 ? 199 LEU D O 1 ATOM 6358 C CB . LEU D 1 218 ? -27.185 24.069 -47.633 1.00 38.50 ? 199 LEU D CB 1 ATOM 6359 C CG . LEU D 1 218 ? -26.110 23.118 -48.158 1.00 37.71 ? 199 LEU D CG 1 ATOM 6360 C CD1 . LEU D 1 218 ? -25.838 23.401 -49.626 1.00 47.88 ? 199 LEU D CD1 1 ATOM 6361 C CD2 . LEU D 1 218 ? -24.829 23.236 -47.344 1.00 37.36 ? 199 LEU D CD2 1 ATOM 6362 N N . ASN D 1 219 ? -29.331 21.993 -49.529 1.00 43.81 ? 200 ASN D N 1 ATOM 6363 C CA . ASN D 1 219 ? -29.705 20.599 -49.708 1.00 36.59 ? 200 ASN D CA 1 ATOM 6364 C C . ASN D 1 219 ? -28.511 19.815 -50.271 1.00 39.50 ? 200 ASN D C 1 ATOM 6365 O O . ASN D 1 219 ? -28.016 20.115 -51.365 1.00 38.89 ? 200 ASN D O 1 ATOM 6366 C CB . ASN D 1 219 ? -30.955 20.500 -50.599 1.00 43.43 ? 200 ASN D CB 1 ATOM 6367 C CG . ASN D 1 219 ? -31.470 19.071 -50.743 1.00 49.36 ? 200 ASN D CG 1 ATOM 6368 O OD1 . ASN D 1 219 ? -31.842 18.636 -51.842 1.00 51.70 ? 200 ASN D OD1 1 ATOM 6369 N ND2 . ASN D 1 219 ? -31.474 18.328 -49.639 1.00 44.81 ? 200 ASN D ND2 1 ATOM 6370 N N . PHE D 1 220 ? -28.035 18.828 -49.510 1.00 36.02 ? 201 PHE D N 1 ATOM 6371 C CA . PHE D 1 220 ? -26.814 18.101 -49.866 1.00 30.20 ? 201 PHE D CA 1 ATOM 6372 C C . PHE D 1 220 ? -26.883 16.666 -49.386 1.00 34.16 ? 201 PHE D C 1 ATOM 6373 O O . PHE D 1 220 ? -27.661 16.354 -48.476 1.00 32.69 ? 201 PHE D O 1 ATOM 6374 C CB . PHE D 1 220 ? -25.589 18.776 -49.233 1.00 31.69 ? 201 PHE D CB 1 ATOM 6375 C CG . PHE D 1 220 ? -25.483 18.576 -47.750 1.00 23.74 ? 201 PHE D CG 1 ATOM 6376 C CD1 . PHE D 1 220 ? -26.370 19.205 -46.889 1.00 32.78 ? 201 PHE D CD1 1 ATOM 6377 C CD2 . PHE D 1 220 ? -24.501 17.757 -47.215 1.00 26.00 ? 201 PHE D CD2 1 ATOM 6378 C CE1 . PHE D 1 220 ? -26.292 19.020 -45.508 1.00 28.87 ? 201 PHE D CE1 1 ATOM 6379 C CE2 . PHE D 1 220 ? -24.406 17.558 -45.830 1.00 30.36 ? 201 PHE D CE2 1 ATOM 6380 C CZ . PHE D 1 220 ? -25.305 18.191 -44.978 1.00 29.86 ? 201 PHE D CZ 1 ATOM 6381 N N . ARG D 1 221 ? -26.063 15.795 -49.985 1.00 39.69 ? 202 ARG D N 1 ATOM 6382 C CA . ARG D 1 221 ? -25.955 14.393 -49.545 1.00 34.77 ? 202 ARG D CA 1 ATOM 6383 C C . ARG D 1 221 ? -24.564 13.837 -49.730 1.00 27.99 ? 202 ARG D C 1 ATOM 6384 O O . ARG D 1 221 ? -23.731 14.438 -50.405 1.00 30.32 ? 202 ARG D O 1 ATOM 6385 C CB . ARG D 1 221 ? -26.936 13.497 -50.300 1.00 36.57 ? 202 ARG D CB 1 ATOM 6386 C CG . ARG D 1 221 ? -26.701 13.481 -51.794 1.00 38.84 ? 202 ARG D CG 1 ATOM 6387 C CD . ARG D 1 221 ? -27.009 12.120 -52.426 1.00 43.46 ? 202 ARG D CD 1 ATOM 6388 N NE . ARG D 1 221 ? -26.764 12.171 -53.865 1.00 49.74 ? 202 ARG D NE 1 ATOM 6389 C CZ . ARG D 1 221 ? -27.718 12.299 -54.787 1.00 64.49 ? 202 ARG D CZ 1 ATOM 6390 N NH1 . ARG D 1 221 ? -28.991 12.338 -54.406 1.00 70.06 ? 202 ARG D NH1 1 ATOM 6391 N NH2 . ARG D 1 221 ? -27.405 12.371 -56.088 1.00 52.53 ? 202 ARG D NH2 1 ATOM 6392 N N . LYS D 1 222 ? -24.326 12.672 -49.132 1.00 33.93 ? 203 LYS D N 1 ATOM 6393 C CA . LYS D 1 222 ? -23.072 11.937 -49.317 1.00 32.92 ? 203 LYS D CA 1 ATOM 6394 C C . LYS D 1 222 ? -23.004 11.284 -50.704 1.00 34.80 ? 203 LYS D C 1 ATOM 6395 O O . LYS D 1 222 ? -24.001 10.764 -51.210 1.00 41.18 ? 203 LYS D O 1 ATOM 6396 C CB . LYS D 1 222 ? -22.939 10.874 -48.242 1.00 29.30 ? 203 LYS D CB 1 ATOM 6397 C CG . LYS D 1 222 ? -21.595 10.172 -48.247 1.00 37.99 ? 203 LYS D CG 1 ATOM 6398 C CD . LYS D 1 222 ? -21.523 9.190 -47.083 1.00 56.40 ? 203 LYS D CD 1 ATOM 6399 C CE . LYS D 1 222 ? -20.210 8.432 -47.036 1.00 56.22 ? 203 LYS D CE 1 ATOM 6400 N NZ . LYS D 1 222 ? -20.231 7.445 -45.912 1.00 81.08 ? 203 LYS D NZ 1 ATOM 6401 N N . LYS D 1 223 ? -21.834 11.324 -51.325 1.00 31.46 ? 204 LYS D N 1 ATOM 6402 C CA . LYS D 1 223 ? -21.653 10.746 -52.657 1.00 37.79 ? 204 LYS D CA 1 ATOM 6403 C C . LYS D 1 223 ? -21.649 9.210 -52.601 1.00 42.62 ? 204 LYS D C 1 ATOM 6404 O O . LYS D 1 223 ? -21.301 8.620 -51.577 1.00 40.56 ? 204 LYS D O 1 ATOM 6405 C CB . LYS D 1 223 ? -20.325 11.216 -53.260 1.00 34.95 ? 204 LYS D CB 1 ATOM 6406 C CG . LYS D 1 223 ? -20.260 12.657 -53.712 1.00 30.21 ? 204 LYS D CG 1 ATOM 6407 C CD . LYS D 1 223 ? -18.805 13.005 -53.997 1.00 33.21 ? 204 LYS D CD 1 ATOM 6408 C CE . LYS D 1 223 ? -18.634 14.149 -54.980 1.00 37.94 ? 204 LYS D CE 1 ATOM 6409 N NZ . LYS D 1 223 ? -17.203 14.248 -55.441 1.00 32.23 ? 204 LYS D NZ 1 ATOM 6410 N N . GLY D 1 224 ? -22.009 8.560 -53.703 1.00 39.58 ? 205 GLY D N 1 ATOM 6411 C CA . GLY D 1 224 ? -22.005 7.107 -53.744 1.00 51.84 ? 205 GLY D CA 1 ATOM 6412 C C . GLY D 1 224 ? -20.669 6.536 -54.197 1.00 62.60 ? 205 GLY D C 1 ATOM 6413 O O . GLY D 1 224 ? -20.601 5.624 -55.028 1.00 63.23 ? 205 GLY D O 1 ATOM 6414 N N . LEU E 1 20 ? -28.087 66.936 -33.293 1.00 48.74 ? 1 LEU E N 1 ATOM 6415 C CA . LEU E 1 20 ? -27.180 65.806 -33.156 1.00 34.78 ? 1 LEU E CA 1 ATOM 6416 C C . LEU E 1 20 ? -27.549 64.705 -34.123 1.00 38.08 ? 1 LEU E C 1 ATOM 6417 O O . LEU E 1 20 ? -28.703 64.296 -34.190 1.00 45.36 ? 1 LEU E O 1 ATOM 6418 C CB . LEU E 1 20 ? -27.253 65.235 -31.747 1.00 39.01 ? 1 LEU E CB 1 ATOM 6419 C CG . LEU E 1 20 ? -26.531 65.992 -30.643 1.00 45.96 ? 1 LEU E CG 1 ATOM 6420 C CD1 . LEU E 1 20 ? -26.534 65.148 -29.370 1.00 43.92 ? 1 LEU E CD1 1 ATOM 6421 C CD2 . LEU E 1 20 ? -25.108 66.336 -31.075 1.00 42.97 ? 1 LEU E CD2 1 ATOM 6422 N N . ASP E 1 21 ? -26.568 64.216 -34.868 1.00 42.40 ? 2 ASP E N 1 ATOM 6423 C CA . ASP E 1 21 ? -26.753 62.994 -35.651 1.00 43.43 ? 2 ASP E CA 1 ATOM 6424 C C . ASP E 1 21 ? -25.934 61.855 -35.039 1.00 37.19 ? 2 ASP E C 1 ATOM 6425 O O . ASP E 1 21 ? -25.223 62.065 -34.045 1.00 36.61 ? 2 ASP E O 1 ATOM 6426 C CB . ASP E 1 21 ? -26.373 63.221 -37.120 1.00 50.42 ? 2 ASP E CB 1 ATOM 6427 C CG . ASP E 1 21 ? -25.072 64.022 -37.288 1.00 56.81 ? 2 ASP E CG 1 ATOM 6428 O OD1 . ASP E 1 21 ? -24.113 63.788 -36.519 1.00 54.57 ? 2 ASP E OD1 1 ATOM 6429 O OD2 . ASP E 1 21 ? -25.009 64.884 -38.202 1.00 65.24 ? 2 ASP E OD2 1 ATOM 6430 N N . ARG E 1 22 ? -26.025 60.663 -35.622 1.00 34.00 ? 3 ARG E N 1 ATOM 6431 C CA . ARG E 1 22 ? -25.274 59.522 -35.099 1.00 30.67 ? 3 ARG E CA 1 ATOM 6432 C C . ARG E 1 22 ? -23.776 59.765 -35.050 1.00 27.66 ? 3 ARG E C 1 ATOM 6433 O O . ARG E 1 22 ? -23.111 59.370 -34.083 1.00 24.09 ? 3 ARG E O 1 ATOM 6434 C CB . ARG E 1 22 ? -25.550 58.259 -35.903 1.00 28.74 ? 3 ARG E CB 1 ATOM 6435 C CG . ARG E 1 22 ? -26.856 57.609 -35.584 1.00 33.53 ? 3 ARG E CG 1 ATOM 6436 C CD . ARG E 1 22 ? -27.037 56.348 -36.386 1.00 42.10 ? 3 ARG E CD 1 ATOM 6437 N NE . ARG E 1 22 ? -28.287 55.689 -36.030 1.00 55.89 ? 3 ARG E NE 1 ATOM 6438 C CZ . ARG E 1 22 ? -29.464 56.018 -36.543 1.00 54.31 ? 3 ARG E CZ 1 ATOM 6439 N NH1 . ARG E 1 22 ? -29.539 57.006 -37.440 1.00 43.66 ? 3 ARG E NH1 1 ATOM 6440 N NH2 . ARG E 1 22 ? -30.552 55.357 -36.153 1.00 50.67 ? 3 ARG E NH2 1 ATOM 6441 N N . ALA E 1 23 ? -23.254 60.411 -36.091 1.00 26.40 ? 4 ALA E N 1 ATOM 6442 C CA . ALA E 1 23 ? -21.825 60.689 -36.168 1.00 25.04 ? 4 ALA E CA 1 ATOM 6443 C C . ALA E 1 23 ? -21.357 61.514 -34.966 1.00 29.03 ? 4 ALA E C 1 ATOM 6444 O O . ALA E 1 23 ? -20.328 61.218 -34.352 1.00 30.06 ? 4 ALA E O 1 ATOM 6445 C CB . ALA E 1 23 ? -21.506 61.400 -37.447 1.00 27.77 ? 4 ALA E CB 1 ATOM 6446 N N . ASP E 1 24 ? -22.135 62.538 -34.629 1.00 28.68 ? 5 ASP E N 1 ATOM 6447 C CA . ASP E 1 24 ? -21.845 63.408 -33.503 1.00 25.17 ? 5 ASP E CA 1 ATOM 6448 C C . ASP E 1 24 ? -21.866 62.683 -32.152 1.00 23.75 ? 5 ASP E C 1 ATOM 6449 O O . ASP E 1 24 ? -20.943 62.841 -31.348 1.00 24.83 ? 5 ASP E O 1 ATOM 6450 C CB . ASP E 1 24 ? -22.812 64.598 -33.513 1.00 31.64 ? 5 ASP E CB 1 ATOM 6451 C CG . ASP E 1 24 ? -22.490 65.618 -34.623 1.00 51.17 ? 5 ASP E CG 1 ATOM 6452 O OD1 . ASP E 1 24 ? -21.291 65.770 -35.002 1.00 51.34 ? 5 ASP E OD1 1 ATOM 6453 O OD2 . ASP E 1 24 ? -23.448 66.269 -35.111 1.00 54.31 ? 5 ASP E OD2 1 ATOM 6454 N N . ILE E 1 25 ? -22.905 61.881 -31.919 1.00 23.19 ? 6 ILE E N 1 ATOM 6455 C CA . ILE E 1 25 ? -23.049 61.114 -30.677 1.00 22.00 ? 6 ILE E CA 1 ATOM 6456 C C . ILE E 1 25 ? -21.907 60.119 -30.440 1.00 23.07 ? 6 ILE E C 1 ATOM 6457 O O . ILE E 1 25 ? -21.307 60.075 -29.360 1.00 21.77 ? 6 ILE E O 1 ATOM 6458 C CB . ILE E 1 25 ? -24.399 60.352 -30.640 1.00 25.81 ? 6 ILE E CB 1 ATOM 6459 C CG1 . ILE E 1 25 ? -25.574 61.335 -30.661 1.00 30.26 ? 6 ILE E CG1 1 ATOM 6460 C CG2 . ILE E 1 25 ? -24.494 59.427 -29.409 1.00 22.33 ? 6 ILE E CG2 1 ATOM 6461 C CD1 . ILE E 1 25 ? -26.921 60.662 -30.913 1.00 34.98 ? 6 ILE E CD1 1 ATOM 6462 N N . LEU E 1 26 ? -21.616 59.314 -31.455 1.00 23.77 ? 7 LEU E N 1 ATOM 6463 C CA . LEU E 1 26 ? -20.540 58.343 -31.356 1.00 23.74 ? 7 LEU E CA 1 ATOM 6464 C C . LEU E 1 26 ? -19.196 59.037 -31.142 1.00 23.99 ? 7 LEU E C 1 ATOM 6465 O O . LEU E 1 26 ? -18.335 58.529 -30.415 1.00 28.26 ? 7 LEU E O 1 ATOM 6466 C CB . LEU E 1 26 ? -20.524 57.418 -32.581 1.00 25.43 ? 7 LEU E CB 1 ATOM 6467 C CG . LEU E 1 26 ? -21.767 56.520 -32.641 1.00 22.24 ? 7 LEU E CG 1 ATOM 6468 C CD1 . LEU E 1 26 ? -22.019 55.993 -34.045 1.00 29.89 ? 7 LEU E CD1 1 ATOM 6469 C CD2 . LEU E 1 26 ? -21.657 55.373 -31.673 1.00 13.01 ? 7 LEU E CD2 1 ATOM 6470 N N . TYR E 1 27 ? -19.030 60.207 -31.754 1.00 22.31 ? 8 TYR E N 1 ATOM 6471 C CA . TYR E 1 27 ? -17.835 61.011 -31.552 1.00 20.70 ? 8 TYR E CA 1 ATOM 6472 C C . TYR E 1 27 ? -17.692 61.411 -30.082 1.00 21.94 ? 8 TYR E C 1 ATOM 6473 O O . TYR E 1 27 ? -16.678 61.118 -29.448 1.00 22.21 ? 8 TYR E O 1 ATOM 6474 C CB . TYR E 1 27 ? -17.852 62.248 -32.448 1.00 25.70 ? 8 TYR E CB 1 ATOM 6475 C CG . TYR E 1 27 ? -16.632 63.128 -32.263 1.00 36.08 ? 8 TYR E CG 1 ATOM 6476 C CD1 . TYR E 1 27 ? -15.416 62.783 -32.832 1.00 27.79 ? 8 TYR E CD1 1 ATOM 6477 C CD2 . TYR E 1 27 ? -16.698 64.302 -31.506 1.00 35.89 ? 8 TYR E CD2 1 ATOM 6478 C CE1 . TYR E 1 27 ? -14.296 63.573 -32.663 1.00 32.95 ? 8 TYR E CE1 1 ATOM 6479 C CE2 . TYR E 1 27 ? -15.582 65.108 -31.332 1.00 38.78 ? 8 TYR E CE2 1 ATOM 6480 C CZ . TYR E 1 27 ? -14.379 64.738 -31.913 1.00 47.87 ? 8 TYR E CZ 1 ATOM 6481 O OH . TYR E 1 27 ? -13.260 65.540 -31.736 1.00 48.64 ? 8 TYR E OH 1 ATOM 6482 N N . ASN E 1 28 ? -18.711 62.071 -29.539 1.00 22.12 ? 9 ASN E N 1 ATOM 6483 C CA . ASN E 1 28 ? -18.714 62.418 -28.117 1.00 22.51 ? 9 ASN E CA 1 ATOM 6484 C C . ASN E 1 28 ? -18.435 61.235 -27.203 1.00 20.62 ? 9 ASN E C 1 ATOM 6485 O O . ASN E 1 28 ? -17.649 61.340 -26.261 1.00 17.55 ? 9 ASN E O 1 ATOM 6486 C CB . ASN E 1 28 ? -20.021 63.116 -27.712 1.00 17.41 ? 9 ASN E CB 1 ATOM 6487 C CG . ASN E 1 28 ? -20.230 64.421 -28.452 1.00 20.42 ? 9 ASN E CG 1 ATOM 6488 O OD1 . ASN E 1 28 ? -19.271 65.047 -28.927 1.00 28.76 ? 9 ASN E OD1 1 ATOM 6489 N ND2 . ASN E 1 28 ? -21.489 64.838 -28.570 1.00 18.72 ? 9 ASN E ND2 1 ATOM 6490 N N . ILE E 1 29 ? -19.074 60.104 -27.497 1.00 25.55 ? 10 ILE E N 1 ATOM 6491 C CA . ILE E 1 29 ? -18.872 58.896 -26.694 1.00 27.56 ? 10 ILE E CA 1 ATOM 6492 C C . ILE E 1 29 ? -17.430 58.404 -26.723 1.00 27.66 ? 10 ILE E C 1 ATOM 6493 O O . ILE E 1 29 ? -16.853 58.103 -25.680 1.00 26.66 ? 10 ILE E O 1 ATOM 6494 C CB . ILE E 1 29 ? -19.829 57.762 -27.087 1.00 22.29 ? 10 ILE E CB 1 ATOM 6495 C CG1 . ILE E 1 29 ? -21.273 58.164 -26.741 1.00 25.17 ? 10 ILE E CG1 1 ATOM 6496 C CG2 . ILE E 1 29 ? -19.418 56.473 -26.377 1.00 16.98 ? 10 ILE E CG2 1 ATOM 6497 C CD1 . ILE E 1 29 ? -22.319 57.091 -26.985 1.00 22.12 ? 10 ILE E CD1 1 ATOM 6498 N N . ARG E 1 30 ? -16.842 58.367 -27.914 1.00 24.01 ? 11 ARG E N 1 ATOM 6499 C CA . ARG E 1 30 ? -15.445 57.986 -28.039 1.00 27.04 ? 11 ARG E CA 1 ATOM 6500 C C . ARG E 1 30 ? -14.487 58.879 -27.231 1.00 32.36 ? 11 ARG E C 1 ATOM 6501 O O . ARG E 1 30 ? -13.504 58.390 -26.659 1.00 33.35 ? 11 ARG E O 1 ATOM 6502 C CB . ARG E 1 30 ? -15.024 57.925 -29.513 1.00 29.40 ? 11 ARG E CB 1 ATOM 6503 C CG . ARG E 1 30 ? -14.172 56.711 -29.807 1.00 50.15 ? 11 ARG E CG 1 ATOM 6504 C CD . ARG E 1 30 ? -13.103 56.991 -30.831 1.00 64.90 ? 11 ARG E CD 1 ATOM 6505 N NE . ARG E 1 30 ? -12.018 56.016 -30.717 1.00 77.25 ? 11 ARG E NE 1 ATOM 6506 C CZ . ARG E 1 30 ? -10.922 56.013 -31.472 1.00 84.72 ? 11 ARG E CZ 1 ATOM 6507 N NH1 . ARG E 1 30 ? -10.751 56.935 -32.418 1.00 76.14 ? 11 ARG E NH1 1 ATOM 6508 N NH2 . ARG E 1 30 ? -9.998 55.079 -31.279 1.00 82.56 ? 11 ARG E NH2 1 ATOM 6509 N N . GLN E 1 31 ? -14.793 60.177 -27.167 1.00 31.22 ? 12 GLN E N 1 ATOM 6510 C CA . GLN E 1 31 ? -13.925 61.156 -26.496 1.00 29.70 ? 12 GLN E CA 1 ATOM 6511 C C . GLN E 1 31 ? -14.051 61.254 -24.967 1.00 29.85 ? 12 GLN E C 1 ATOM 6512 O O . GLN E 1 31 ? -13.123 61.717 -24.311 1.00 33.83 ? 12 GLN E O 1 ATOM 6513 C CB . GLN E 1 31 ? -14.125 62.560 -27.086 1.00 26.55 ? 12 GLN E CB 1 ATOM 6514 C CG . GLN E 1 31 ? -13.891 62.686 -28.583 1.00 34.50 ? 12 GLN E CG 1 ATOM 6515 C CD . GLN E 1 31 ? -12.435 62.466 -28.970 1.00 45.21 ? 12 GLN E CD 1 ATOM 6516 O OE1 . GLN E 1 31 ? -11.543 62.491 -28.116 1.00 50.12 ? 12 GLN E OE1 1 ATOM 6517 N NE2 . GLN E 1 31 ? -12.188 62.243 -30.261 1.00 41.28 ? 12 GLN E NE2 1 ATOM 6518 N N . THR E 1 32 ? -15.203 60.968 -24.412 1.00 24.90 ? 13 THR E N 1 ATOM 6519 C CA . THR E 1 32 ? -15.450 61.295 -23.044 1.00 28.64 ? 13 THR E CA 1 ATOM 6520 C C . THR E 1 32 ? -15.850 60.139 -22.197 1.00 38.54 ? 13 THR E C 1 ATOM 6521 O O . THR E 1 32 ? -16.259 60.311 -21.077 1.00 39.26 ? 13 THR E O 1 ATOM 6522 C CB . THR E 1 32 ? -16.576 62.326 -22.944 1.00 28.46 ? 13 THR E CB 1 ATOM 6523 O OG1 . THR E 1 32 ? -17.753 61.776 -23.490 1.00 33.69 ? 13 THR E OG1 1 ATOM 6524 C CG2 . THR E 1 32 ? -16.262 63.549 -23.697 1.00 22.28 ? 13 THR E CG2 1 ATOM 6525 N N . SER E 1 33 ? -15.849 58.963 -22.781 1.00 47.52 ? 14 SER E N 1 ATOM 6526 C CA . SER E 1 33 ? -16.471 57.781 -22.195 1.00 39.15 ? 14 SER E CA 1 ATOM 6527 C C . SER E 1 33 ? -15.925 57.204 -20.895 1.00 43.11 ? 14 SER E C 1 ATOM 6528 O O . SER E 1 33 ? -16.699 56.913 -20.020 1.00 41.31 ? 14 SER E O 1 ATOM 6529 C CB . SER E 1 33 ? -16.519 56.696 -23.238 1.00 25.96 ? 14 SER E CB 1 ATOM 6530 O OG . SER E 1 33 ? -17.049 55.541 -22.707 1.00 32.48 ? 14 SER E OG 1 ATOM 6531 N N . ARG E 1 34 ? -14.613 57.098 -20.742 1.00 35.08 ? 15 ARG E N 1 ATOM 6532 C CA . ARG E 1 34 ? -14.031 56.446 -19.583 1.00 34.21 ? 15 ARG E CA 1 ATOM 6533 C C . ARG E 1 34 ? -14.336 54.968 -19.369 1.00 30.38 ? 15 ARG E C 1 ATOM 6534 O O . ARG E 1 34 ? -15.041 54.615 -18.492 1.00 31.49 ? 15 ARG E O 1 ATOM 6535 C CB . ARG E 1 34 ? -14.383 57.223 -18.315 1.00 34.51 ? 15 ARG E CB 1 ATOM 6536 C CG . ARG E 1 34 ? -13.931 58.660 -18.260 1.00 37.42 ? 15 ARG E CG 1 ATOM 6537 C CD . ARG E 1 34 ? -12.480 58.897 -18.651 1.00 43.73 ? 15 ARG E CD 1 ATOM 6538 N NE . ARG E 1 34 ? -11.466 58.265 -17.808 1.00 51.22 ? 15 ARG E NE 1 ATOM 6539 C CZ . ARG E 1 34 ? -11.051 58.682 -16.622 1.00 38.35 ? 15 ARG E CZ 1 ATOM 6540 N NH1 . ARG E 1 34 ? -11.563 59.734 -16.060 1.00 45.82 ? 15 ARG E NH1 1 ATOM 6541 N NH2 . ARG E 1 34 ? -10.130 58.011 -16.003 1.00 27.29 ? 15 ARG E NH2 1 ATOM 6542 N N . PRO E 1 35 ? -13.748 54.098 -20.257 1.00 19.46 ? 16 PRO E N 1 ATOM 6543 C CA . PRO E 1 35 ? -14.116 52.688 -20.144 1.00 19.50 ? 16 PRO E CA 1 ATOM 6544 C C . PRO E 1 35 ? -13.746 51.831 -18.950 1.00 21.63 ? 16 PRO E C 1 ATOM 6545 O O . PRO E 1 35 ? -14.134 50.725 -18.776 1.00 20.12 ? 16 PRO E O 1 ATOM 6546 C CB . PRO E 1 35 ? -13.433 52.076 -21.335 1.00 19.95 ? 16 PRO E CB 1 ATOM 6547 C CG . PRO E 1 35 ? -13.343 53.145 -22.280 1.00 23.65 ? 16 PRO E CG 1 ATOM 6548 C CD . PRO E 1 35 ? -12.781 54.166 -21.419 1.00 22.74 ? 16 PRO E CD 1 ATOM 6549 N N . ASP E 1 36 ? -12.807 52.270 -18.125 1.00 23.29 ? 17 ASP E N 1 ATOM 6550 C CA A ASP E 1 36 ? -12.087 52.019 -16.894 0.42 22.26 ? 17 ASP E CA 1 ATOM 6551 C CA B ASP E 1 36 ? -12.106 52.184 -16.794 0.58 21.39 ? 17 ASP E CA 1 ATOM 6552 C C . ASP E 1 36 ? -12.804 52.507 -15.425 1.00 22.72 ? 17 ASP E C 1 ATOM 6553 O O . ASP E 1 36 ? -12.739 52.110 -14.241 1.00 31.06 ? 17 ASP E O 1 ATOM 6554 C CB A ASP E 1 36 ? -10.618 52.495 -16.872 0.42 23.80 ? 17 ASP E CB 1 ATOM 6555 C CB B ASP E 1 36 ? -10.656 52.594 -16.935 0.58 23.56 ? 17 ASP E CB 1 ATOM 6556 C CG A ASP E 1 36 ? -10.468 54.029 -17.067 0.42 26.78 ? 17 ASP E CG 1 ATOM 6557 C CG B ASP E 1 36 ? -9.921 51.740 -17.953 0.58 24.35 ? 17 ASP E CG 1 ATOM 6558 O OD1 A ASP E 1 36 ? -11.184 54.641 -17.904 0.42 23.80 ? 17 ASP E OD1 1 ATOM 6559 O OD1 B ASP E 1 36 ? -10.280 50.594 -18.158 0.58 23.07 ? 17 ASP E OD1 1 ATOM 6560 O OD2 A ASP E 1 36 ? -9.603 54.624 -16.380 0.42 26.50 ? 17 ASP E OD2 1 ATOM 6561 O OD2 B ASP E 1 36 ? -8.953 52.199 -18.570 0.58 23.44 ? 17 ASP E OD2 1 ATOM 6562 N N . VAL E 1 37 ? -13.724 53.410 -15.750 1.00 20.25 ? 18 VAL E N 1 ATOM 6563 C CA . VAL E 1 37 ? -14.398 53.995 -14.591 1.00 17.68 ? 18 VAL E CA 1 ATOM 6564 C C . VAL E 1 37 ? -15.824 53.497 -14.410 1.00 17.02 ? 18 VAL E C 1 ATOM 6565 O O . VAL E 1 37 ? -16.689 53.769 -15.228 1.00 20.96 ? 18 VAL E O 1 ATOM 6566 C CB . VAL E 1 37 ? -14.479 55.521 -14.681 1.00 19.79 ? 18 VAL E CB 1 ATOM 6567 C CG1 . VAL E 1 37 ? -15.234 56.077 -13.468 1.00 12.47 ? 18 VAL E CG1 1 ATOM 6568 C CG2 . VAL E 1 37 ? -13.101 56.129 -14.814 1.00 27.50 ? 18 VAL E CG2 1 ATOM 6569 N N . ILE E 1 38 ? -16.065 52.783 -13.320 1.00 19.47 ? 19 ILE E N 1 ATOM 6570 C CA . ILE E 1 38 ? -17.400 52.294 -12.976 1.00 18.40 ? 19 ILE E CA 1 ATOM 6571 C C . ILE E 1 38 ? -18.376 53.466 -12.739 1.00 22.13 ? 19 ILE E C 1 ATOM 6572 O O . ILE E 1 38 ? -18.068 54.414 -12.000 1.00 22.63 ? 19 ILE E O 1 ATOM 6573 C CB . ILE E 1 38 ? -17.319 51.320 -11.751 1.00 21.12 ? 19 ILE E CB 1 ATOM 6574 C CG1 . ILE E 1 38 ? -18.672 50.713 -11.390 1.00 18.42 ? 19 ILE E CG1 1 ATOM 6575 C CG2 . ILE E 1 38 ? -16.700 52.000 -10.530 1.00 18.77 ? 19 ILE E CG2 1 ATOM 6576 C CD1 . ILE E 1 38 ? -18.538 49.586 -10.384 1.00 15.32 ? 19 ILE E CD1 1 ATOM 6577 N N . PRO E 1 39 ? -19.556 53.417 -13.390 1.00 22.37 ? 20 PRO E N 1 ATOM 6578 C CA . PRO E 1 39 ? -20.499 54.545 -13.343 1.00 25.68 ? 20 PRO E CA 1 ATOM 6579 C C . PRO E 1 39 ? -21.398 54.524 -12.094 1.00 24.61 ? 20 PRO E C 1 ATOM 6580 O O . PRO E 1 39 ? -22.620 54.423 -12.187 1.00 23.93 ? 20 PRO E O 1 ATOM 6581 C CB . PRO E 1 39 ? -21.317 54.364 -14.637 1.00 22.15 ? 20 PRO E CB 1 ATOM 6582 C CG . PRO E 1 39 ? -21.310 52.879 -14.889 1.00 15.92 ? 20 PRO E CG 1 ATOM 6583 C CD . PRO E 1 39 ? -20.015 52.345 -14.299 1.00 18.72 ? 20 PRO E CD 1 ATOM 6584 N N . THR E 1 40 ? -20.784 54.622 -10.924 1.00 27.63 ? 21 THR E N 1 ATOM 6585 C CA . THR E 1 40 ? -21.546 54.657 -9.680 1.00 32.70 ? 21 THR E CA 1 ATOM 6586 C C . THR E 1 40 ? -22.229 56.002 -9.562 1.00 44.28 ? 21 THR E C 1 ATOM 6587 O O . THR E 1 40 ? -21.746 57.000 -10.100 1.00 45.08 ? 21 THR E O 1 ATOM 6588 C CB . THR E 1 40 ? -20.659 54.421 -8.440 1.00 34.29 ? 21 THR E CB 1 ATOM 6589 O OG1 . THR E 1 40 ? -19.567 55.353 -8.443 1.00 45.05 ? 21 THR E OG1 1 ATOM 6590 C CG2 . THR E 1 40 ? -20.113 52.987 -8.432 1.00 27.30 ? 21 THR E CG2 1 ATOM 6591 N N . GLN E 1 41 ? -23.407 56.013 -8.975 1.00 59.69 ? 22 GLN E N 1 ATOM 6592 C CA . GLN E 1 41 ? -24.087 57.249 -8.722 1.00 55.40 ? 22 GLN E CA 1 ATOM 6593 C C . GLN E 1 41 ? -24.202 57.374 -7.246 1.00 55.45 ? 22 GLN E C 1 ATOM 6594 O O . GLN E 1 41 ? -24.999 56.725 -6.636 1.00 60.46 ? 22 GLN E O 1 ATOM 6595 C CB . GLN E 1 41 ? -25.482 57.212 -9.337 1.00 49.07 ? 22 GLN E CB 1 ATOM 6596 C CG . GLN E 1 41 ? -25.571 57.842 -10.699 1.00 53.66 ? 22 GLN E CG 1 ATOM 6597 C CD . GLN E 1 41 ? -26.938 57.724 -11.335 1.00 76.60 ? 22 GLN E CD 1 ATOM 6598 O OE1 . GLN E 1 41 ? -27.422 56.633 -11.562 1.00 79.49 ? 22 GLN E OE1 1 ATOM 6599 N NE2 . GLN E 1 41 ? -27.553 58.860 -11.665 1.00 81.50 ? 22 GLN E NE2 1 ATOM 6600 N N . ARG E 1 42 ? -23.453 58.277 -6.677 1.00 57.21 ? 23 ARG E N 1 ATOM 6601 C CA . ARG E 1 42 ? -23.635 58.622 -5.282 1.00 74.70 ? 23 ARG E CA 1 ATOM 6602 C C . ARG E 1 42 ? -23.529 57.484 -4.287 1.00 67.69 ? 23 ARG E C 1 ATOM 6603 O O . ARG E 1 42 ? -24.340 57.359 -3.388 1.00 66.79 ? 23 ARG E O 1 ATOM 6604 C CB . ARG E 1 42 ? -24.965 59.340 -5.106 1.00 76.19 ? 23 ARG E CB 1 ATOM 6605 C CG . ARG E 1 42 ? -25.327 60.216 -6.276 1.00 77.17 ? 23 ARG E CG 1 ATOM 6606 C CD . ARG E 1 42 ? -26.207 61.341 -5.819 1.00 83.54 ? 23 ARG E CD 1 ATOM 6607 N NE . ARG E 1 42 ? -27.199 61.671 -6.811 1.00 84.47 ? 23 ARG E NE 1 ATOM 6608 C CZ . ARG E 1 42 ? -28.307 62.323 -6.528 1.00 91.06 ? 23 ARG E CZ 1 ATOM 6609 N NH1 . ARG E 1 42 ? -28.538 62.694 -5.285 1.00 87.48 ? 23 ARG E NH1 1 ATOM 6610 N NH2 . ARG E 1 42 ? -29.188 62.581 -7.485 1.00 92.29 ? 23 ARG E NH2 1 ATOM 6611 N N . ASP E 1 43 ? -22.531 56.646 -4.452 1.00 66.51 ? 24 ASP E N 1 ATOM 6612 C CA . ASP E 1 43 ? -22.283 55.609 -3.477 1.00 75.37 ? 24 ASP E CA 1 ATOM 6613 C C . ASP E 1 43 ? -23.347 54.533 -3.498 1.00 67.82 ? 24 ASP E C 1 ATOM 6614 O O . ASP E 1 43 ? -23.525 53.802 -2.545 1.00 65.08 ? 24 ASP E O 1 ATOM 6615 C CB . ASP E 1 43 ? -22.173 56.220 -2.090 1.00 74.76 ? 24 ASP E CB 1 ATOM 6616 C CG . ASP E 1 43 ? -20.739 56.371 -1.630 1.00 82.87 ? 24 ASP E CG 1 ATOM 6617 O OD1 . ASP E 1 43 ? -19.840 55.934 -2.365 1.00 84.43 ? 24 ASP E OD1 1 ATOM 6618 O OD2 . ASP E 1 43 ? -20.511 56.914 -0.526 1.00 81.65 ? 24 ASP E OD2 1 ATOM 6619 N N . ARG E 1 44 ? -24.030 54.430 -4.617 1.00 57.16 ? 25 ARG E N 1 ATOM 6620 C CA . ARG E 1 44 ? -25.009 53.410 -4.819 1.00 48.63 ? 25 ARG E CA 1 ATOM 6621 C C . ARG E 1 44 ? -24.411 52.480 -5.794 1.00 44.87 ? 25 ARG E C 1 ATOM 6622 O O . ARG E 1 44 ? -23.573 52.869 -6.562 1.00 50.26 ? 25 ARG E O 1 ATOM 6623 C CB . ARG E 1 44 ? -26.261 54.007 -5.386 1.00 53.59 ? 25 ARG E CB 1 ATOM 6624 C CG . ARG E 1 44 ? -27.039 54.799 -4.366 1.00 69.68 ? 25 ARG E CG 1 ATOM 6625 C CD . ARG E 1 44 ? -28.373 55.245 -4.904 1.00 74.90 ? 25 ARG E CD 1 ATOM 6626 N NE . ARG E 1 44 ? -28.987 56.165 -3.961 1.00 109.05 ? 25 ARG E NE 1 ATOM 6627 C CZ . ARG E 1 44 ? -29.081 57.486 -4.117 1.00 117.90 ? 25 ARG E CZ 1 ATOM 6628 N NH1 . ARG E 1 44 ? -28.615 58.068 -5.224 1.00 116.64 ? 25 ARG E NH1 1 ATOM 6629 N NH2 . ARG E 1 44 ? -29.663 58.220 -3.161 1.00 106.46 ? 25 ARG E NH2 1 ATOM 6630 N N . PRO E 1 45 ? -24.827 51.170 -5.699 1.00 35.96 ? 26 PRO E N 1 ATOM 6631 C CA . PRO E 1 45 ? -24.181 50.250 -6.638 1.00 29.56 ? 26 PRO E CA 1 ATOM 6632 C C . PRO E 1 45 ? -24.626 50.467 -8.038 1.00 24.36 ? 26 PRO E C 1 ATOM 6633 O O . PRO E 1 45 ? -25.557 51.177 -8.203 1.00 28.92 ? 26 PRO E O 1 ATOM 6634 C CB . PRO E 1 45 ? -24.705 48.913 -6.215 1.00 30.33 ? 26 PRO E CB 1 ATOM 6635 C CG . PRO E 1 45 ? -25.000 49.061 -4.817 1.00 32.67 ? 26 PRO E CG 1 ATOM 6636 C CD . PRO E 1 45 ? -25.707 50.329 -4.785 1.00 24.03 ? 26 PRO E CD 1 ATOM 6637 N N . VAL E 1 46 ? -23.941 49.930 -9.031 1.00 23.45 ? 27 VAL E N 1 ATOM 6638 C CA . VAL E 1 46 ? -24.506 49.920 -10.363 1.00 18.96 ? 27 VAL E CA 1 ATOM 6639 C C . VAL E 1 46 ? -25.364 48.690 -10.383 1.00 18.73 ? 27 VAL E C 1 ATOM 6640 O O . VAL E 1 46 ? -24.884 47.601 -10.071 1.00 22.99 ? 27 VAL E O 1 ATOM 6641 C CB . VAL E 1 46 ? -23.411 49.787 -11.419 1.00 22.17 ? 27 VAL E CB 1 ATOM 6642 C CG1 . VAL E 1 46 ? -24.012 49.689 -12.811 1.00 19.95 ? 27 VAL E CG1 1 ATOM 6643 C CG2 . VAL E 1 46 ? -22.433 50.971 -11.321 1.00 25.53 ? 27 VAL E CG2 1 ATOM 6644 N N . ALA E 1 47 ? -26.638 48.841 -10.722 1.00 21.46 ? 28 ALA E N 1 ATOM 6645 C CA . ALA E 1 47 ? -27.504 47.662 -10.813 1.00 23.79 ? 28 ALA E CA 1 ATOM 6646 C C . ALA E 1 47 ? -27.373 46.982 -12.175 1.00 26.05 ? 28 ALA E C 1 ATOM 6647 O O . ALA E 1 47 ? -27.813 47.521 -13.193 1.00 28.00 ? 28 ALA E O 1 ATOM 6648 C CB . ALA E 1 47 ? -28.937 48.019 -10.534 1.00 17.14 ? 28 ALA E CB 1 ATOM 6649 N N . VAL E 1 48 ? -26.769 45.797 -12.186 1.00 21.39 ? 29 VAL E N 1 ATOM 6650 C CA . VAL E 1 48 ? -26.640 45.023 -13.412 1.00 21.71 ? 29 VAL E CA 1 ATOM 6651 C C . VAL E 1 48 ? -27.691 43.903 -13.432 1.00 25.58 ? 29 VAL E C 1 ATOM 6652 O O . VAL E 1 48 ? -27.819 43.149 -12.473 1.00 25.16 ? 29 VAL E O 1 ATOM 6653 C CB . VAL E 1 48 ? -25.242 44.394 -13.513 1.00 21.38 ? 29 VAL E CB 1 ATOM 6654 C CG1 . VAL E 1 48 ? -25.079 43.640 -14.838 1.00 14.12 ? 29 VAL E CG1 1 ATOM 6655 C CG2 . VAL E 1 48 ? -24.163 45.459 -13.320 1.00 16.33 ? 29 VAL E CG2 1 ATOM 6656 N N . SER E 1 49 ? -28.441 43.794 -14.521 1.00 22.60 ? 30 SER E N 1 ATOM 6657 C CA . SER E 1 49 ? -29.341 42.671 -14.697 1.00 20.26 ? 30 SER E CA 1 ATOM 6658 C C . SER E 1 49 ? -28.716 41.665 -15.635 1.00 28.37 ? 30 SER E C 1 ATOM 6659 O O . SER E 1 49 ? -28.145 42.043 -16.662 1.00 34.51 ? 30 SER E O 1 ATOM 6660 C CB . SER E 1 49 ? -30.632 43.134 -15.315 1.00 25.37 ? 30 SER E CB 1 ATOM 6661 O OG . SER E 1 49 ? -30.997 44.364 -14.748 1.00 44.60 ? 30 SER E OG 1 ATOM 6662 N N . VAL E 1 50 ? -28.840 40.384 -15.291 1.00 29.08 ? 31 VAL E N 1 ATOM 6663 C CA . VAL E 1 50 ? -28.281 39.303 -16.094 1.00 25.63 ? 31 VAL E CA 1 ATOM 6664 C C . VAL E 1 50 ? -29.353 38.287 -16.430 1.00 26.22 ? 31 VAL E C 1 ATOM 6665 O O . VAL E 1 50 ? -30.122 37.884 -15.564 1.00 34.06 ? 31 VAL E O 1 ATOM 6666 C CB . VAL E 1 50 ? -27.148 38.584 -15.358 1.00 24.50 ? 31 VAL E CB 1 ATOM 6667 C CG1 . VAL E 1 50 ? -26.557 37.511 -16.242 1.00 25.07 ? 31 VAL E CG1 1 ATOM 6668 C CG2 . VAL E 1 50 ? -26.067 39.572 -14.961 1.00 21.94 ? 31 VAL E CG2 1 ATOM 6669 N N . SER E 1 51 ? -29.403 37.870 -17.689 1.00 22.90 ? 32 SER E N 1 ATOM 6670 C CA . SER E 1 51 ? -30.366 36.862 -18.115 1.00 27.29 ? 32 SER E CA 1 ATOM 6671 C C . SER E 1 51 ? -29.741 35.920 -19.155 1.00 25.74 ? 32 SER E C 1 ATOM 6672 O O . SER E 1 51 ? -29.200 36.378 -20.166 1.00 31.73 ? 32 SER E O 1 ATOM 6673 C CB . SER E 1 51 ? -31.611 37.555 -18.680 1.00 28.67 ? 32 SER E CB 1 ATOM 6674 O OG . SER E 1 51 ? -32.597 36.612 -19.062 1.00 44.27 ? 32 SER E OG 1 ATOM 6675 N N . LEU E 1 52 ? -29.800 34.615 -18.917 1.00 18.87 ? 33 LEU E N 1 ATOM 6676 C CA . LEU E 1 52 ? -29.317 33.660 -19.930 1.00 26.32 ? 33 LEU E CA 1 ATOM 6677 C C . LEU E 1 52 ? -30.444 33.081 -20.819 1.00 28.17 ? 33 LEU E C 1 ATOM 6678 O O . LEU E 1 52 ? -31.451 32.569 -20.332 1.00 33.11 ? 33 LEU E O 1 ATOM 6679 C CB . LEU E 1 52 ? -28.521 32.511 -19.297 1.00 21.43 ? 33 LEU E CB 1 ATOM 6680 C CG . LEU E 1 52 ? -27.461 32.917 -18.275 1.00 22.42 ? 33 LEU E CG 1 ATOM 6681 C CD1 . LEU E 1 52 ? -26.588 31.742 -17.896 1.00 25.25 ? 33 LEU E CD1 1 ATOM 6682 C CD2 . LEU E 1 52 ? -26.606 34.032 -18.814 1.00 26.31 ? 33 LEU E CD2 1 ATOM 6683 N N . LYS E 1 53 ? -30.269 33.168 -22.128 1.00 24.85 ? 34 LYS E N 1 ATOM 6684 C CA . LYS E 1 53 ? -31.179 32.527 -23.045 1.00 21.35 ? 34 LYS E CA 1 ATOM 6685 C C . LYS E 1 53 ? -30.434 31.334 -23.657 1.00 24.70 ? 34 LYS E C 1 ATOM 6686 O O . LYS E 1 53 ? -29.460 31.512 -24.411 1.00 20.35 ? 34 LYS E O 1 ATOM 6687 C CB . LYS E 1 53 ? -31.603 33.501 -24.142 1.00 17.00 ? 34 LYS E CB 1 ATOM 6688 C CG . LYS E 1 53 ? -31.897 34.893 -23.651 1.00 24.85 ? 34 LYS E CG 1 ATOM 6689 C CD . LYS E 1 53 ? -33.223 34.989 -22.915 1.00 36.40 ? 34 LYS E CD 1 ATOM 6690 C CE . LYS E 1 53 ? -33.517 36.433 -22.487 1.00 42.62 ? 34 LYS E CE 1 ATOM 6691 N NZ . LYS E 1 53 ? -34.782 36.537 -21.669 1.00 51.15 ? 34 LYS E NZ 1 ATOM 6692 N N . PHE E 1 54 ? -30.880 30.119 -23.351 1.00 19.50 ? 35 PHE E N 1 ATOM 6693 C CA . PHE E 1 54 ? -30.172 28.966 -23.864 1.00 15.89 ? 35 PHE E CA 1 ATOM 6694 C C . PHE E 1 54 ? -30.483 28.722 -25.315 1.00 17.05 ? 35 PHE E C 1 ATOM 6695 O O . PHE E 1 54 ? -31.620 28.834 -25.737 1.00 20.20 ? 35 PHE E O 1 ATOM 6696 C CB . PHE E 1 54 ? -30.432 27.754 -23.000 1.00 19.29 ? 35 PHE E CB 1 ATOM 6697 C CG . PHE E 1 54 ? -29.903 27.915 -21.624 1.00 19.83 ? 35 PHE E CG 1 ATOM 6698 C CD1 . PHE E 1 54 ? -28.582 27.629 -21.341 1.00 16.40 ? 35 PHE E CD1 1 ATOM 6699 C CD2 . PHE E 1 54 ? -30.712 28.412 -20.614 1.00 25.16 ? 35 PHE E CD2 1 ATOM 6700 C CE1 . PHE E 1 54 ? -28.083 27.808 -20.049 1.00 17.27 ? 35 PHE E CE1 1 ATOM 6701 C CE2 . PHE E 1 54 ? -30.221 28.598 -19.327 1.00 18.32 ? 35 PHE E CE2 1 ATOM 6702 C CZ . PHE E 1 54 ? -28.908 28.306 -19.049 1.00 16.36 ? 35 PHE E CZ 1 ATOM 6703 N N . ILE E 1 55 ? -29.443 28.425 -26.079 1.00 19.71 ? 36 ILE E N 1 ATOM 6704 C CA . ILE E 1 55 ? -29.579 28.210 -27.512 1.00 24.68 ? 36 ILE E CA 1 ATOM 6705 C C . ILE E 1 55 ? -29.281 26.750 -27.881 1.00 25.93 ? 36 ILE E C 1 ATOM 6706 O O . ILE E 1 55 ? -29.940 26.174 -28.753 1.00 29.89 ? 36 ILE E O 1 ATOM 6707 C CB . ILE E 1 55 ? -28.666 29.175 -28.328 1.00 21.72 ? 36 ILE E CB 1 ATOM 6708 C CG1 . ILE E 1 55 ? -28.790 30.615 -27.808 1.00 17.56 ? 36 ILE E CG1 1 ATOM 6709 C CG2 . ILE E 1 55 ? -28.981 29.100 -29.813 1.00 14.42 ? 36 ILE E CG2 1 ATOM 6710 C CD1 . ILE E 1 55 ? -30.193 31.154 -27.795 1.00 15.83 ? 36 ILE E CD1 1 ATOM 6711 N N . ASN E 1 56 ? -28.297 26.150 -27.215 1.00 21.98 ? 37 ASN E N 1 ATOM 6712 C CA . ASN E 1 56 ? -27.937 24.771 -27.518 1.00 22.74 ? 37 ASN E CA 1 ATOM 6713 C C . ASN E 1 56 ? -27.215 24.071 -26.379 1.00 25.85 ? 37 ASN E C 1 ATOM 6714 O O . ASN E 1 56 ? -26.561 24.718 -25.560 1.00 25.36 ? 37 ASN E O 1 ATOM 6715 C CB . ASN E 1 56 ? -27.061 24.733 -28.768 1.00 24.00 ? 37 ASN E CB 1 ATOM 6716 C CG . ASN E 1 56 ? -27.422 23.601 -29.700 1.00 24.19 ? 37 ASN E CG 1 ATOM 6717 O OD1 . ASN E 1 56 ? -27.608 22.463 -29.277 1.00 26.18 ? 37 ASN E OD1 1 ATOM 6718 N ND2 . ASN E 1 56 ? -27.527 23.911 -30.981 1.00 28.99 ? 37 ASN E ND2 1 ATOM 6719 N N . ILE E 1 57 ? -27.342 22.746 -26.333 1.00 27.17 ? 38 ILE E N 1 ATOM 6720 C CA . ILE E 1 57 ? -26.542 21.916 -25.437 1.00 22.22 ? 38 ILE E CA 1 ATOM 6721 C C . ILE E 1 57 ? -25.797 20.901 -26.294 1.00 21.10 ? 38 ILE E C 1 ATOM 6722 O O . ILE E 1 57 ? -26.402 20.228 -27.118 1.00 25.28 ? 38 ILE E O 1 ATOM 6723 C CB . ILE E 1 57 ? -27.400 21.266 -24.361 1.00 18.88 ? 38 ILE E CB 1 ATOM 6724 C CG1 . ILE E 1 57 ? -28.053 22.365 -23.514 1.00 21.86 ? 38 ILE E CG1 1 ATOM 6725 C CG2 . ILE E 1 57 ? -26.548 20.355 -23.491 1.00 17.61 ? 38 ILE E CG2 1 ATOM 6726 C CD1 . ILE E 1 57 ? -29.086 21.887 -22.506 1.00 18.69 ? 38 ILE E CD1 1 ATOM 6727 N N . LEU E 1 58 ? -24.480 20.822 -26.140 1.00 23.56 ? 39 LEU E N 1 ATOM 6728 C CA . LEU E 1 58 ? -23.671 20.260 -27.214 1.00 25.90 ? 39 LEU E CA 1 ATOM 6729 C C . LEU E 1 58 ? -22.960 18.996 -26.860 1.00 29.05 ? 39 LEU E C 1 ATOM 6730 O O . LEU E 1 58 ? -23.039 18.027 -27.606 1.00 42.08 ? 39 LEU E O 1 ATOM 6731 C CB . LEU E 1 58 ? -22.648 21.278 -27.722 1.00 29.57 ? 39 LEU E CB 1 ATOM 6732 C CG . LEU E 1 58 ? -23.240 22.415 -28.542 1.00 30.02 ? 39 LEU E CG 1 ATOM 6733 C CD1 . LEU E 1 58 ? -22.146 23.342 -28.979 1.00 34.24 ? 39 LEU E CD1 1 ATOM 6734 C CD2 . LEU E 1 58 ? -23.984 21.852 -29.757 1.00 35.75 ? 39 LEU E CD2 1 ATOM 6735 N N . GLU E 1 59 ? -22.237 19.002 -25.749 1.00 31.38 ? 40 GLU E N 1 ATOM 6736 C CA . GLU E 1 59 ? -21.417 17.842 -25.423 1.00 40.10 ? 40 GLU E CA 1 ATOM 6737 C C . GLU E 1 59 ? -21.514 17.527 -23.966 1.00 39.66 ? 40 GLU E C 1 ATOM 6738 O O . GLU E 1 59 ? -20.885 18.176 -23.133 1.00 41.07 ? 40 GLU E O 1 ATOM 6739 C CB . GLU E 1 59 ? -19.958 18.046 -25.826 1.00 39.60 ? 40 GLU E CB 1 ATOM 6740 C CG . GLU E 1 59 ? -19.530 17.179 -26.995 1.00 49.17 ? 40 GLU E CG 1 ATOM 6741 C CD . GLU E 1 59 ? -18.483 17.852 -27.872 1.00 61.36 ? 40 GLU E CD 1 ATOM 6742 O OE1 . GLU E 1 59 ? -18.102 19.013 -27.575 1.00 59.86 ? 40 GLU E OE1 1 ATOM 6743 O OE2 . GLU E 1 59 ? -18.047 17.214 -28.859 1.00 71.46 ? 40 GLU E OE2 1 ATOM 6744 N N . VAL E 1 60 ? -22.310 16.517 -23.662 1.00 33.38 ? 41 VAL E N 1 ATOM 6745 C CA . VAL E 1 60 ? -22.517 16.157 -22.284 1.00 29.02 ? 41 VAL E CA 1 ATOM 6746 C C . VAL E 1 60 ? -21.670 14.946 -21.953 1.00 31.94 ? 41 VAL E C 1 ATOM 6747 O O . VAL E 1 60 ? -21.530 14.036 -22.776 1.00 33.72 ? 41 VAL E O 1 ATOM 6748 C CB . VAL E 1 60 ? -23.987 15.919 -22.039 1.00 29.93 ? 41 VAL E CB 1 ATOM 6749 C CG1 . VAL E 1 60 ? -24.211 15.381 -20.677 1.00 30.29 ? 41 VAL E CG1 1 ATOM 6750 C CG2 . VAL E 1 60 ? -24.713 17.231 -22.209 1.00 35.07 ? 41 VAL E CG2 1 ATOM 6751 N N . ASN E 1 61 ? -21.050 14.975 -20.777 1.00 28.15 ? 42 ASN E N 1 ATOM 6752 C CA . ASN E 1 61 ? -20.312 13.824 -20.278 1.00 33.70 ? 42 ASN E CA 1 ATOM 6753 C C . ASN E 1 61 ? -20.746 13.536 -18.840 1.00 38.00 ? 42 ASN E C 1 ATOM 6754 O O . ASN E 1 61 ? -20.395 14.275 -17.917 1.00 35.32 ? 42 ASN E O 1 ATOM 6755 C CB . ASN E 1 61 ? -18.796 14.057 -20.387 1.00 30.14 ? 42 ASN E CB 1 ATOM 6756 C CG . ASN E 1 61 ? -17.969 12.789 -20.105 1.00 35.91 ? 42 ASN E CG 1 ATOM 6757 O OD1 . ASN E 1 61 ? -18.301 11.980 -19.222 1.00 31.98 ? 42 ASN E OD1 1 ATOM 6758 N ND2 . ASN E 1 61 ? -16.882 12.620 -20.859 1.00 35.77 ? 42 ASN E ND2 1 ATOM 6759 N N . GLU E 1 62 ? -21.528 12.470 -18.658 1.00 35.97 ? 43 GLU E N 1 ATOM 6760 C CA . GLU E 1 62 ? -22.027 12.112 -17.331 1.00 34.08 ? 43 GLU E CA 1 ATOM 6761 C C . GLU E 1 62 ? -20.895 11.556 -16.446 1.00 37.09 ? 43 GLU E C 1 ATOM 6762 O O . GLU E 1 62 ? -20.925 11.692 -15.217 1.00 37.53 ? 43 GLU E O 1 ATOM 6763 C CB . GLU E 1 62 ? -23.207 11.126 -17.437 1.00 38.86 ? 43 GLU E CB 1 ATOM 6764 C CG . GLU E 1 62 ? -24.112 11.041 -16.181 1.00 45.97 ? 43 GLU E CG 1 ATOM 6765 C CD . GLU E 1 62 ? -25.326 10.092 -16.349 1.00 58.20 ? 43 GLU E CD 1 ATOM 6766 O OE1 . GLU E 1 62 ? -25.622 9.681 -17.502 1.00 54.02 ? 43 GLU E OE1 1 ATOM 6767 O OE2 . GLU E 1 62 ? -25.987 9.763 -15.323 1.00 53.04 ? 43 GLU E OE2 1 ATOM 6768 N N . ILE E 1 63 ? -19.888 10.952 -17.078 1.00 31.59 ? 44 ILE E N 1 ATOM 6769 C CA . ILE E 1 63 ? -18.744 10.404 -16.339 1.00 34.85 ? 44 ILE E CA 1 ATOM 6770 C C . ILE E 1 63 ? -17.914 11.490 -15.651 1.00 35.41 ? 44 ILE E C 1 ATOM 6771 O O . ILE E 1 63 ? -17.540 11.339 -14.482 1.00 29.27 ? 44 ILE E O 1 ATOM 6772 C CB . ILE E 1 63 ? -17.761 9.586 -17.235 1.00 40.94 ? 44 ILE E CB 1 ATOM 6773 C CG1 . ILE E 1 63 ? -18.472 8.465 -18.016 1.00 30.77 ? 44 ILE E CG1 1 ATOM 6774 C CG2 . ILE E 1 63 ? -16.593 9.065 -16.393 1.00 31.72 ? 44 ILE E CG2 1 ATOM 6775 C CD1 . ILE E 1 63 ? -19.101 7.401 -17.163 1.00 25.82 ? 44 ILE E CD1 1 ATOM 6776 N N . THR E 1 64 ? -17.613 12.569 -16.388 1.00 39.53 ? 45 THR E N 1 ATOM 6777 C CA . THR E 1 64 ? -16.730 13.640 -15.892 1.00 30.27 ? 45 THR E CA 1 ATOM 6778 C C . THR E 1 64 ? -17.485 14.833 -15.373 1.00 26.21 ? 45 THR E C 1 ATOM 6779 O O . THR E 1 64 ? -16.875 15.780 -14.897 1.00 27.89 ? 45 THR E O 1 ATOM 6780 C CB . THR E 1 64 ? -15.780 14.166 -16.965 1.00 25.08 ? 45 THR E CB 1 ATOM 6781 O OG1 . THR E 1 64 ? -16.541 14.849 -17.958 1.00 32.90 ? 45 THR E OG1 1 ATOM 6782 C CG2 . THR E 1 64 ? -15.010 13.032 -17.629 1.00 33.62 ? 45 THR E CG2 1 ATOM 6783 N N . ASN E 1 65 ? -18.810 14.797 -15.480 1.00 29.03 ? 46 ASN E N 1 ATOM 6784 C CA . ASN E 1 65 ? -19.645 15.934 -15.067 1.00 34.04 ? 46 ASN E CA 1 ATOM 6785 C C . ASN E 1 65 ? -19.305 17.291 -15.739 1.00 28.23 ? 46 ASN E C 1 ATOM 6786 O O . ASN E 1 65 ? -19.028 18.284 -15.061 1.00 23.51 ? 46 ASN E O 1 ATOM 6787 C CB . ASN E 1 65 ? -19.643 16.077 -13.546 1.00 33.89 ? 46 ASN E CB 1 ATOM 6788 C CG . ASN E 1 65 ? -20.735 15.261 -12.874 1.00 34.61 ? 46 ASN E CG 1 ATOM 6789 O OD1 . ASN E 1 65 ? -21.730 14.874 -13.496 1.00 33.76 ? 46 ASN E OD1 1 ATOM 6790 N ND2 . ASN E 1 65 ? -20.559 15.010 -11.579 1.00 37.26 ? 46 ASN E ND2 1 ATOM 6791 N N . GLU E 1 66 ? -19.338 17.306 -17.072 1.00 26.43 ? 47 GLU E N 1 ATOM 6792 C CA . GLU E 1 66 ? -19.025 18.484 -17.853 1.00 25.88 ? 47 GLU E CA 1 ATOM 6793 C C . GLU E 1 66 ? -20.058 18.673 -18.959 1.00 31.29 ? 47 GLU E C 1 ATOM 6794 O O . GLU E 1 66 ? -20.478 17.698 -19.587 1.00 30.99 ? 47 GLU E O 1 ATOM 6795 C CB . GLU E 1 66 ? -17.631 18.349 -18.453 1.00 26.52 ? 47 GLU E CB 1 ATOM 6796 C CG . GLU E 1 66 ? -16.541 18.241 -17.417 1.00 30.07 ? 47 GLU E CG 1 ATOM 6797 C CD . GLU E 1 66 ? -15.141 18.113 -18.018 1.00 41.31 ? 47 GLU E CD 1 ATOM 6798 O OE1 . GLU E 1 66 ? -14.989 18.307 -19.259 1.00 42.20 ? 47 GLU E OE1 1 ATOM 6799 O OE2 . GLU E 1 66 ? -14.193 17.820 -17.230 1.00 37.78 ? 47 GLU E OE2 1 ATOM 6800 N N . VAL E 1 67 ? -20.466 19.923 -19.192 1.00 30.37 ? 48 VAL E N 1 ATOM 6801 C CA . VAL E 1 67 ? -21.381 20.238 -20.288 1.00 24.95 ? 48 VAL E CA 1 ATOM 6802 C C . VAL E 1 67 ? -20.843 21.360 -21.155 1.00 26.36 ? 48 VAL E C 1 ATOM 6803 O O . VAL E 1 67 ? -20.023 22.161 -20.717 1.00 24.57 ? 48 VAL E O 1 ATOM 6804 C CB . VAL E 1 67 ? -22.787 20.620 -19.788 1.00 25.48 ? 48 VAL E CB 1 ATOM 6805 C CG1 . VAL E 1 67 ? -23.360 19.520 -18.933 1.00 31.88 ? 48 VAL E CG1 1 ATOM 6806 C CG2 . VAL E 1 67 ? -22.727 21.868 -18.980 1.00 27.06 ? 48 VAL E CG2 1 ATOM 6807 N N . ASP E 1 68 ? -21.318 21.395 -22.397 1.00 35.62 ? 49 ASP E N 1 ATOM 6808 C CA . ASP E 1 68 ? -20.965 22.421 -23.370 1.00 24.53 ? 49 ASP E CA 1 ATOM 6809 C C . ASP E 1 68 ? -22.218 23.185 -23.743 1.00 24.37 ? 49 ASP E C 1 ATOM 6810 O O . ASP E 1 68 ? -23.109 22.644 -24.386 1.00 24.39 ? 49 ASP E O 1 ATOM 6811 C CB . ASP E 1 68 ? -20.423 21.763 -24.619 1.00 26.28 ? 49 ASP E CB 1 ATOM 6812 C CG . ASP E 1 68 ? -19.116 22.326 -25.024 1.00 34.11 ? 49 ASP E CG 1 ATOM 6813 O OD1 . ASP E 1 68 ? -18.466 22.904 -24.134 1.00 48.87 ? 49 ASP E OD1 1 ATOM 6814 O OD2 . ASP E 1 68 ? -18.736 22.195 -26.209 1.00 37.13 ? 49 ASP E OD2 1 ATOM 6815 N N . VAL E 1 69 ? -22.299 24.440 -23.342 1.00 26.20 ? 50 VAL E N 1 ATOM 6816 C CA . VAL E 1 69 ? -23.510 25.205 -23.572 1.00 21.86 ? 50 VAL E CA 1 ATOM 6817 C C . VAL E 1 69 ? -23.288 26.401 -24.511 1.00 21.75 ? 50 VAL E C 1 ATOM 6818 O O . VAL E 1 69 ? -22.227 27.038 -24.500 1.00 19.28 ? 50 VAL E O 1 ATOM 6819 C CB . VAL E 1 69 ? -24.084 25.656 -22.233 1.00 23.21 ? 50 VAL E CB 1 ATOM 6820 C CG1 . VAL E 1 69 ? -25.409 26.368 -22.428 1.00 27.70 ? 50 VAL E CG1 1 ATOM 6821 C CG2 . VAL E 1 69 ? -24.264 24.444 -21.340 1.00 22.20 ? 50 VAL E CG2 1 ATOM 6822 N N . VAL E 1 70 ? -24.288 26.671 -25.349 1.00 20.79 ? 51 VAL E N 1 ATOM 6823 C CA . VAL E 1 70 ? -24.350 27.915 -26.100 1.00 17.04 ? 51 VAL E CA 1 ATOM 6824 C C . VAL E 1 70 ? -25.539 28.702 -25.567 1.00 17.75 ? 51 VAL E C 1 ATOM 6825 O O . VAL E 1 70 ? -26.658 28.178 -25.508 1.00 20.32 ? 51 VAL E O 1 ATOM 6826 C CB . VAL E 1 70 ? -24.500 27.658 -27.616 1.00 13.92 ? 51 VAL E CB 1 ATOM 6827 C CG1 . VAL E 1 70 ? -24.799 28.943 -28.335 1.00 14.24 ? 51 VAL E CG1 1 ATOM 6828 C CG2 . VAL E 1 70 ? -23.242 27.012 -28.180 1.00 13.05 ? 51 VAL E CG2 1 ATOM 6829 N N . PHE E 1 71 ? -25.299 29.950 -25.173 1.00 15.90 ? 52 PHE E N 1 ATOM 6830 C CA . PHE E 1 71 ? -26.359 30.799 -24.628 1.00 16.83 ? 52 PHE E CA 1 ATOM 6831 C C . PHE E 1 71 ? -26.116 32.284 -24.914 1.00 16.03 ? 52 PHE E C 1 ATOM 6832 O O . PHE E 1 71 ? -24.980 32.686 -25.116 1.00 17.03 ? 52 PHE E O 1 ATOM 6833 C CB . PHE E 1 71 ? -26.435 30.587 -23.122 1.00 18.30 ? 52 PHE E CB 1 ATOM 6834 C CG . PHE E 1 71 ? -25.154 30.888 -22.419 1.00 19.93 ? 52 PHE E CG 1 ATOM 6835 C CD1 . PHE E 1 71 ? -24.148 29.928 -22.355 1.00 22.93 ? 52 PHE E CD1 1 ATOM 6836 C CD2 . PHE E 1 71 ? -24.937 32.136 -21.840 1.00 17.49 ? 52 PHE E CD2 1 ATOM 6837 C CE1 . PHE E 1 71 ? -22.938 30.205 -21.718 1.00 22.90 ? 52 PHE E CE1 1 ATOM 6838 C CE2 . PHE E 1 71 ? -23.740 32.425 -21.199 1.00 17.38 ? 52 PHE E CE2 1 ATOM 6839 C CZ . PHE E 1 71 ? -22.736 31.456 -21.136 1.00 19.11 ? 52 PHE E CZ 1 ATOM 6840 N N . TRP E 1 72 ? -27.180 33.088 -24.938 1.00 17.54 ? 53 TRP E N 1 ATOM 6841 C CA . TRP E 1 72 ? -27.047 34.551 -24.998 1.00 17.70 ? 53 TRP E CA 1 ATOM 6842 C C . TRP E 1 72 ? -26.961 35.065 -23.582 1.00 18.21 ? 53 TRP E C 1 ATOM 6843 O O . TRP E 1 72 ? -27.767 34.690 -22.730 1.00 15.53 ? 53 TRP E O 1 ATOM 6844 C CB . TRP E 1 72 ? -28.254 35.234 -25.654 1.00 16.62 ? 53 TRP E CB 1 ATOM 6845 C CG . TRP E 1 72 ? -28.504 34.874 -27.080 1.00 15.86 ? 53 TRP E CG 1 ATOM 6846 C CD1 . TRP E 1 72 ? -27.765 34.032 -27.853 1.00 17.20 ? 53 TRP E CD1 1 ATOM 6847 C CD2 . TRP E 1 72 ? -29.578 35.340 -27.904 1.00 16.18 ? 53 TRP E CD2 1 ATOM 6848 N NE1 . TRP E 1 72 ? -28.317 33.938 -29.104 1.00 16.90 ? 53 TRP E NE1 1 ATOM 6849 C CE2 . TRP E 1 72 ? -29.437 34.734 -29.164 1.00 11.19 ? 53 TRP E CE2 1 ATOM 6850 C CE3 . TRP E 1 72 ? -30.658 36.219 -27.698 1.00 20.11 ? 53 TRP E CE3 1 ATOM 6851 C CZ2 . TRP E 1 72 ? -30.312 34.964 -30.217 1.00 13.33 ? 53 TRP E CZ2 1 ATOM 6852 C CZ3 . TRP E 1 72 ? -31.532 36.458 -28.744 1.00 22.11 ? 53 TRP E CZ3 1 ATOM 6853 C CH2 . TRP E 1 72 ? -31.351 35.832 -29.992 1.00 22.16 ? 53 TRP E CH2 1 ATOM 6854 N N . GLN E 1 73 ? -25.995 35.941 -23.328 1.00 17.40 ? 54 GLN E N 1 ATOM 6855 C CA . GLN E 1 73 ? -25.828 36.481 -21.984 1.00 19.47 ? 54 GLN E CA 1 ATOM 6856 C C . GLN E 1 73 ? -26.312 37.920 -21.916 1.00 19.01 ? 54 GLN E C 1 ATOM 6857 O O . GLN E 1 73 ? -25.537 38.856 -22.000 1.00 21.38 ? 54 GLN E O 1 ATOM 6858 C CB . GLN E 1 73 ? -24.371 36.374 -21.532 1.00 19.13 ? 54 GLN E CB 1 ATOM 6859 C CG . GLN E 1 73 ? -24.144 36.859 -20.110 1.00 19.32 ? 54 GLN E CG 1 ATOM 6860 C CD . GLN E 1 73 ? -22.725 36.615 -19.635 1.00 27.72 ? 54 GLN E CD 1 ATOM 6861 O OE1 . GLN E 1 73 ? -22.238 35.473 -19.609 1.00 18.60 ? 54 GLN E OE1 1 ATOM 6862 N NE2 . GLN E 1 73 ? -22.039 37.698 -19.265 1.00 39.79 ? 54 GLN E NE2 1 ATOM 6863 N N . GLN E 1 74 ? -27.611 38.098 -21.764 1.00 21.68 ? 55 GLN E N 1 ATOM 6864 C CA . GLN E 1 74 ? -28.182 39.430 -21.859 1.00 22.28 ? 55 GLN E CA 1 ATOM 6865 C C . GLN E 1 74 ? -27.870 40.236 -20.603 1.00 27.83 ? 55 GLN E C 1 ATOM 6866 O O . GLN E 1 74 ? -28.335 39.906 -19.500 1.00 24.17 ? 55 GLN E O 1 ATOM 6867 C CB . GLN E 1 74 ? -29.686 39.337 -22.063 1.00 23.77 ? 55 GLN E CB 1 ATOM 6868 C CG . GLN E 1 74 ? -30.359 40.685 -22.086 1.00 33.94 ? 55 GLN E CG 1 ATOM 6869 C CD . GLN E 1 74 ? -31.852 40.593 -22.366 1.00 40.95 ? 55 GLN E CD 1 ATOM 6870 O OE1 . GLN E 1 74 ? -32.297 39.733 -23.133 1.00 51.72 ? 55 GLN E OE1 1 ATOM 6871 N NE2 . GLN E 1 74 ? -32.631 41.485 -21.751 1.00 36.90 ? 55 GLN E NE2 1 ATOM 6872 N N . THR E 1 75 ? -27.086 41.301 -20.780 1.00 27.74 ? 56 THR E N 1 ATOM 6873 C CA . THR E 1 75 ? -26.593 42.100 -19.658 1.00 21.86 ? 56 THR E CA 1 ATOM 6874 C C . THR E 1 75 ? -27.060 43.548 -19.796 1.00 22.49 ? 56 THR E C 1 ATOM 6875 O O . THR E 1 75 ? -26.906 44.150 -20.861 1.00 21.57 ? 56 THR E O 1 ATOM 6876 C CB . THR E 1 75 ? -25.047 42.058 -19.571 1.00 19.79 ? 56 THR E CB 1 ATOM 6877 O OG1 . THR E 1 75 ? -24.562 40.724 -19.784 1.00 25.17 ? 56 THR E OG1 1 ATOM 6878 C CG2 . THR E 1 75 ? -24.590 42.528 -18.211 1.00 19.95 ? 56 THR E CG2 1 ATOM 6879 N N . THR E 1 76 ? -27.617 44.111 -18.723 1.00 22.23 ? 57 THR E N 1 ATOM 6880 C CA . THR E 1 76 ? -28.213 45.451 -18.785 1.00 21.90 ? 57 THR E CA 1 ATOM 6881 C C . THR E 1 76 ? -27.889 46.342 -17.580 1.00 25.71 ? 57 THR E C 1 ATOM 6882 O O . THR E 1 76 ? -28.012 45.909 -16.434 1.00 30.42 ? 57 THR E O 1 ATOM 6883 C CB . THR E 1 76 ? -29.732 45.342 -18.934 1.00 27.44 ? 57 THR E CB 1 ATOM 6884 O OG1 . THR E 1 76 ? -30.041 44.794 -20.231 1.00 31.37 ? 57 THR E OG1 1 ATOM 6885 C CG2 . THR E 1 76 ? -30.391 46.718 -18.802 1.00 40.67 ? 57 THR E CG2 1 ATOM 6886 N N . TRP E 1 77 ? -27.477 47.583 -17.834 1.00 23.35 ? 58 TRP E N 1 ATOM 6887 C CA . TRP E 1 77 ? -27.151 48.507 -16.748 1.00 18.25 ? 58 TRP E CA 1 ATOM 6888 C C . TRP E 1 77 ? -27.294 49.951 -17.187 1.00 20.34 ? 58 TRP E C 1 ATOM 6889 O O . TRP E 1 77 ? -27.575 50.247 -18.348 1.00 20.02 ? 58 TRP E O 1 ATOM 6890 C CB . TRP E 1 77 ? -25.732 48.269 -16.230 1.00 17.25 ? 58 TRP E CB 1 ATOM 6891 C CG . TRP E 1 77 ? -24.696 48.662 -17.213 1.00 15.55 ? 58 TRP E CG 1 ATOM 6892 C CD1 . TRP E 1 77 ? -24.059 49.863 -17.290 1.00 17.09 ? 58 TRP E CD1 1 ATOM 6893 C CD2 . TRP E 1 77 ? -24.188 47.868 -18.286 1.00 15.37 ? 58 TRP E CD2 1 ATOM 6894 N NE1 . TRP E 1 77 ? -23.179 49.865 -18.339 1.00 17.29 ? 58 TRP E NE1 1 ATOM 6895 C CE2 . TRP E 1 77 ? -23.236 48.647 -18.971 1.00 14.23 ? 58 TRP E CE2 1 ATOM 6896 C CE3 . TRP E 1 77 ? -24.447 46.568 -18.737 1.00 13.47 ? 58 TRP E CE3 1 ATOM 6897 C CZ2 . TRP E 1 77 ? -22.526 48.178 -20.070 1.00 11.96 ? 58 TRP E CZ2 1 ATOM 6898 C CZ3 . TRP E 1 77 ? -23.743 46.097 -19.832 1.00 14.25 ? 58 TRP E CZ3 1 ATOM 6899 C CH2 . TRP E 1 77 ? -22.791 46.904 -20.490 1.00 13.62 ? 58 TRP E CH2 1 ATOM 6900 N N . SER E 1 78 ? -27.073 50.862 -16.253 1.00 21.62 ? 59 SER E N 1 ATOM 6901 C CA . SER E 1 78 ? -27.243 52.263 -16.568 1.00 17.53 ? 59 SER E CA 1 ATOM 6902 C C . SER E 1 78 ? -25.946 53.049 -16.433 1.00 19.37 ? 59 SER E C 1 ATOM 6903 O O . SER E 1 78 ? -25.208 52.876 -15.458 1.00 21.18 ? 59 SER E O 1 ATOM 6904 C CB . SER E 1 78 ? -28.319 52.855 -15.683 1.00 20.06 ? 59 SER E CB 1 ATOM 6905 O OG . SER E 1 78 ? -28.502 54.214 -16.005 1.00 37.59 ? 59 SER E OG 1 ATOM 6906 N N . ASP E 1 79 ? -25.674 53.915 -17.417 1.00 23.14 ? 60 ASP E N 1 ATOM 6907 C CA . ASP E 1 79 ? -24.478 54.771 -17.418 1.00 24.64 ? 60 ASP E CA 1 ATOM 6908 C C . ASP E 1 79 ? -24.800 56.183 -17.907 1.00 26.45 ? 60 ASP E C 1 ATOM 6909 O O . ASP E 1 79 ? -24.747 56.450 -19.112 1.00 27.02 ? 60 ASP E O 1 ATOM 6910 C CB . ASP E 1 79 ? -23.373 54.148 -18.281 1.00 21.13 ? 60 ASP E CB 1 ATOM 6911 C CG . ASP E 1 79 ? -22.007 54.802 -18.068 1.00 27.59 ? 60 ASP E CG 1 ATOM 6912 O OD1 . ASP E 1 79 ? -21.949 55.974 -17.608 1.00 31.63 ? 60 ASP E OD1 1 ATOM 6913 O OD2 . ASP E 1 79 ? -20.988 54.134 -18.363 1.00 24.94 ? 60 ASP E OD2 1 ATOM 6914 N N . ARG E 1 80 ? -25.104 57.083 -16.970 1.00 25.85 ? 61 ARG E N 1 ATOM 6915 C CA . ARG E 1 80 ? -25.557 58.440 -17.304 1.00 29.58 ? 61 ARG E CA 1 ATOM 6916 C C . ARG E 1 80 ? -24.519 59.262 -18.051 1.00 25.27 ? 61 ARG E C 1 ATOM 6917 O O . ARG E 1 80 ? -24.865 60.215 -18.735 1.00 36.84 ? 61 ARG E O 1 ATOM 6918 C CB . ARG E 1 80 ? -26.008 59.197 -16.050 1.00 32.39 ? 61 ARG E CB 1 ATOM 6919 C CG . ARG E 1 80 ? -26.952 58.408 -15.148 1.00 49.22 ? 61 ARG E CG 1 ATOM 6920 C CD . ARG E 1 80 ? -28.405 58.390 -15.637 1.00 55.40 ? 61 ARG E CD 1 ATOM 6921 N NE . ARG E 1 80 ? -29.304 57.851 -14.606 1.00 73.26 ? 61 ARG E NE 1 ATOM 6922 C CZ . ARG E 1 80 ? -30.159 56.842 -14.786 1.00 76.19 ? 61 ARG E CZ 1 ATOM 6923 N NH1 . ARG E 1 80 ? -30.255 56.257 -15.975 1.00 71.80 ? 61 ARG E NH1 1 ATOM 6924 N NH2 . ARG E 1 80 ? -30.927 56.420 -13.779 1.00 69.19 ? 61 ARG E NH2 1 ATOM 6925 N N . THR E 1 81 ? -23.250 58.907 -17.906 1.00 20.80 ? 62 THR E N 1 ATOM 6926 C CA . THR E 1 81 ? -22.170 59.525 -18.676 1.00 20.39 ? 62 THR E CA 1 ATOM 6927 C C . THR E 1 81 ? -22.419 59.479 -20.197 1.00 29.28 ? 62 THR E C 1 ATOM 6928 O O . THR E 1 81 ? -21.913 60.310 -20.944 1.00 33.76 ? 62 THR E O 1 ATOM 6929 C CB . THR E 1 81 ? -20.858 58.785 -18.368 1.00 25.50 ? 62 THR E CB 1 ATOM 6930 O OG1 . THR E 1 81 ? -20.621 58.827 -16.958 1.00 29.06 ? 62 THR E OG1 1 ATOM 6931 C CG2 . THR E 1 81 ? -19.656 59.354 -19.127 1.00 28.90 ? 62 THR E CG2 1 ATOM 6932 N N . LEU E 1 82 ? -23.196 58.500 -20.656 1.00 30.26 ? 63 LEU E N 1 ATOM 6933 C CA . LEU E 1 82 ? -23.406 58.302 -22.086 1.00 23.27 ? 63 LEU E CA 1 ATOM 6934 C C . LEU E 1 82 ? -24.610 59.070 -22.625 1.00 20.51 ? 63 LEU E C 1 ATOM 6935 O O . LEU E 1 82 ? -24.840 59.134 -23.840 1.00 19.52 ? 63 LEU E O 1 ATOM 6936 C CB . LEU E 1 82 ? -23.571 56.807 -22.374 1.00 21.73 ? 63 LEU E CB 1 ATOM 6937 C CG . LEU E 1 82 ? -22.425 55.900 -21.924 1.00 22.29 ? 63 LEU E CG 1 ATOM 6938 C CD1 . LEU E 1 82 ? -22.848 54.444 -22.001 1.00 19.22 ? 63 LEU E CD1 1 ATOM 6939 C CD2 . LEU E 1 82 ? -21.178 56.133 -22.782 1.00 18.93 ? 63 LEU E CD2 1 ATOM 6940 N N . ALA E 1 83 ? -25.389 59.652 -21.726 1.00 21.72 ? 64 ALA E N 1 ATOM 6941 C CA . ALA E 1 83 ? -26.694 60.188 -22.110 1.00 23.47 ? 64 ALA E CA 1 ATOM 6942 C C . ALA E 1 83 ? -26.581 61.410 -23.017 1.00 23.40 ? 64 ALA E C 1 ATOM 6943 O O . ALA E 1 83 ? -25.579 62.123 -22.991 1.00 28.70 ? 64 ALA E O 1 ATOM 6944 C CB . ALA E 1 83 ? -27.515 60.507 -20.888 1.00 22.35 ? 64 ALA E CB 1 ATOM 6945 N N . TRP E 1 84 ? -27.605 61.633 -23.829 1.00 20.87 ? 65 TRP E N 1 ATOM 6946 C CA . TRP E 1 84 ? -27.685 62.835 -24.660 1.00 28.08 ? 65 TRP E CA 1 ATOM 6947 C C . TRP E 1 84 ? -29.138 63.353 -24.776 1.00 31.74 ? 65 TRP E C 1 ATOM 6948 O O . TRP E 1 84 ? -30.087 62.653 -24.415 1.00 35.51 ? 65 TRP E O 1 ATOM 6949 C CB . TRP E 1 84 ? -27.046 62.594 -26.045 1.00 25.93 ? 65 TRP E CB 1 ATOM 6950 C CG . TRP E 1 84 ? -27.781 61.621 -26.954 1.00 27.85 ? 65 TRP E CG 1 ATOM 6951 C CD1 . TRP E 1 84 ? -28.723 61.932 -27.890 1.00 31.59 ? 65 TRP E CD1 1 ATOM 6952 C CD2 . TRP E 1 84 ? -27.616 60.187 -27.014 1.00 29.40 ? 65 TRP E CD2 1 ATOM 6953 N NE1 . TRP E 1 84 ? -29.166 60.786 -28.522 1.00 30.54 ? 65 TRP E NE1 1 ATOM 6954 C CE2 . TRP E 1 84 ? -28.495 59.704 -28.011 1.00 29.75 ? 65 TRP E CE2 1 ATOM 6955 C CE3 . TRP E 1 84 ? -26.813 59.267 -26.319 1.00 23.79 ? 65 TRP E CE3 1 ATOM 6956 C CZ2 . TRP E 1 84 ? -28.596 58.340 -28.333 1.00 31.15 ? 65 TRP E CZ2 1 ATOM 6957 C CZ3 . TRP E 1 84 ? -26.909 57.920 -26.640 1.00 21.06 ? 65 TRP E CZ3 1 ATOM 6958 C CH2 . TRP E 1 84 ? -27.796 57.465 -27.640 1.00 26.54 ? 65 TRP E CH2 1 ATOM 6959 N N . ASN E 1 85 ? -29.313 64.580 -25.256 1.00 35.39 ? 66 ASN E N 1 ATOM 6960 C CA . ASN E 1 85 ? -30.653 65.111 -25.526 1.00 45.51 ? 66 ASN E CA 1 ATOM 6961 C C . ASN E 1 85 ? -31.183 64.543 -26.857 1.00 45.81 ? 66 ASN E C 1 ATOM 6962 O O . ASN E 1 85 ? -30.661 64.881 -27.924 1.00 46.16 ? 66 ASN E O 1 ATOM 6963 C CB . ASN E 1 85 ? -30.610 66.653 -25.568 1.00 43.08 ? 66 ASN E CB 1 ATOM 6964 C CG . ASN E 1 85 ? -31.995 67.297 -25.547 1.00 52.14 ? 66 ASN E CG 1 ATOM 6965 O OD1 . ASN E 1 85 ? -33.004 66.666 -25.890 1.00 63.47 ? 66 ASN E OD1 1 ATOM 6966 N ND2 . ASN E 1 85 ? -32.046 68.573 -25.155 1.00 49.22 ? 66 ASN E ND2 1 ATOM 6967 N N . SER E 1 86 ? -32.211 63.689 -26.802 1.00 47.09 ? 67 SER E N 1 ATOM 6968 C CA . SER E 1 86 ? -32.713 63.034 -28.022 1.00 53.12 ? 67 SER E CA 1 ATOM 6969 C C . SER E 1 86 ? -33.879 63.778 -28.678 1.00 58.49 ? 67 SER E C 1 ATOM 6970 O O . SER E 1 86 ? -34.689 63.171 -29.375 1.00 67.14 ? 67 SER E O 1 ATOM 6971 C CB . SER E 1 86 ? -33.105 61.573 -27.752 1.00 47.65 ? 67 SER E CB 1 ATOM 6972 O OG . SER E 1 86 ? -34.351 61.484 -27.085 1.00 54.35 ? 67 SER E OG 1 ATOM 6973 N N . SER E 1 87 ? -33.942 65.090 -28.465 1.00 63.37 ? 68 SER E N 1 ATOM 6974 C CA . SER E 1 87 ? -35.032 65.923 -28.969 1.00 65.54 ? 68 SER E CA 1 ATOM 6975 C C . SER E 1 87 ? -35.281 65.778 -30.484 1.00 64.50 ? 68 SER E C 1 ATOM 6976 O O . SER E 1 87 ? -36.336 65.299 -30.906 1.00 65.93 ? 68 SER E O 1 ATOM 6977 C CB . SER E 1 87 ? -34.786 67.385 -28.589 1.00 64.22 ? 68 SER E CB 1 ATOM 6978 O OG . SER E 1 87 ? -35.930 68.174 -28.844 1.00 77.56 ? 68 SER E OG 1 ATOM 6979 N N . HIS E 1 88 ? -34.319 66.193 -31.299 1.00 60.14 ? 69 HIS E N 1 ATOM 6980 C CA . HIS E 1 88 ? -34.426 65.988 -32.742 1.00 70.24 ? 69 HIS E CA 1 ATOM 6981 C C . HIS E 1 88 ? -33.269 65.117 -33.213 1.00 68.68 ? 69 HIS E C 1 ATOM 6982 O O . HIS E 1 88 ? -32.584 65.425 -34.194 1.00 60.49 ? 69 HIS E O 1 ATOM 6983 C CB . HIS E 1 88 ? -34.448 67.322 -33.487 1.00 77.18 ? 69 HIS E CB 1 ATOM 6984 C CG . HIS E 1 88 ? -35.620 68.183 -33.135 1.00 85.40 ? 69 HIS E CG 1 ATOM 6985 N ND1 . HIS E 1 88 ? -36.898 67.926 -33.590 1.00 88.95 ? 69 HIS E ND1 1 ATOM 6986 C CD2 . HIS E 1 88 ? -35.709 69.288 -32.360 1.00 86.43 ? 69 HIS E CD2 1 ATOM 6987 C CE1 . HIS E 1 88 ? -37.722 68.842 -33.113 1.00 87.31 ? 69 HIS E CE1 1 ATOM 6988 N NE2 . HIS E 1 88 ? -37.027 69.683 -32.369 1.00 93.38 ? 69 HIS E NE2 1 ATOM 6989 N N . SER E 1 89 ? -33.078 64.013 -32.498 1.00 64.54 ? 70 SER E N 1 ATOM 6990 C CA . SER E 1 89 ? -31.884 63.205 -32.622 1.00 49.52 ? 70 SER E CA 1 ATOM 6991 C C . SER E 1 89 ? -32.248 61.745 -32.530 1.00 46.57 ? 70 SER E C 1 ATOM 6992 O O . SER E 1 89 ? -33.344 61.405 -32.065 1.00 43.58 ? 70 SER E O 1 ATOM 6993 C CB . SER E 1 89 ? -30.928 63.558 -31.487 1.00 47.35 ? 70 SER E CB 1 ATOM 6994 O OG . SER E 1 89 ? -30.677 64.953 -31.460 1.00 60.99 ? 70 SER E OG 1 ATOM 6995 N N . PRO E 1 90 ? -31.330 60.868 -32.971 1.00 41.61 ? 71 PRO E N 1 ATOM 6996 C CA . PRO E 1 90 ? -31.541 59.431 -32.747 1.00 38.42 ? 71 PRO E CA 1 ATOM 6997 C C . PRO E 1 90 ? -31.638 59.142 -31.250 1.00 35.17 ? 71 PRO E C 1 ATOM 6998 O O . PRO E 1 90 ? -30.987 59.809 -30.442 1.00 38.27 ? 71 PRO E O 1 ATOM 6999 C CB . PRO E 1 90 ? -30.271 58.788 -33.326 1.00 38.29 ? 71 PRO E CB 1 ATOM 7000 C CG . PRO E 1 90 ? -29.719 59.799 -34.296 1.00 38.64 ? 71 PRO E CG 1 ATOM 7001 C CD . PRO E 1 90 ? -30.095 61.150 -33.733 1.00 37.18 ? 71 PRO E CD 1 ATOM 7002 N N . ASP E 1 91 ? -32.438 58.156 -30.877 1.00 34.26 ? 72 ASP E N 1 ATOM 7003 C CA . ASP E 1 91 ? -32.586 57.818 -29.468 1.00 42.85 ? 72 ASP E CA 1 ATOM 7004 C C . ASP E 1 91 ? -31.759 56.582 -29.092 1.00 37.94 ? 72 ASP E C 1 ATOM 7005 O O . ASP E 1 91 ? -31.770 56.146 -27.937 1.00 33.21 ? 72 ASP E O 1 ATOM 7006 C CB . ASP E 1 91 ? -34.067 57.611 -29.138 1.00 49.85 ? 72 ASP E CB 1 ATOM 7007 C CG . ASP E 1 91 ? -34.774 56.782 -30.189 1.00 54.47 ? 72 ASP E CG 1 ATOM 7008 O OD1 . ASP E 1 91 ? -34.124 56.477 -31.221 1.00 52.30 ? 72 ASP E OD1 1 ATOM 7009 O OD2 . ASP E 1 91 ? -35.968 56.442 -29.992 1.00 72.00 ? 72 ASP E OD2 1 ATOM 7010 N N . GLN E 1 92 ? -31.033 56.041 -30.070 1.00 37.14 ? 73 GLN E N 1 ATOM 7011 C CA . GLN E 1 92 ? -30.175 54.880 -29.849 1.00 35.87 ? 73 GLN E CA 1 ATOM 7012 C C . GLN E 1 92 ? -28.993 54.805 -30.834 1.00 31.70 ? 73 GLN E C 1 ATOM 7013 O O . GLN E 1 92 ? -29.077 55.301 -31.959 1.00 35.08 ? 73 GLN E O 1 ATOM 7014 C CB . GLN E 1 92 ? -31.004 53.621 -29.983 1.00 32.01 ? 73 GLN E CB 1 ATOM 7015 C CG . GLN E 1 92 ? -31.674 53.579 -31.319 1.00 45.91 ? 73 GLN E CG 1 ATOM 7016 C CD . GLN E 1 92 ? -32.286 52.252 -31.605 1.00 54.70 ? 73 GLN E CD 1 ATOM 7017 O OE1 . GLN E 1 92 ? -32.891 51.632 -30.724 1.00 59.18 ? 73 GLN E OE1 1 ATOM 7018 N NE2 . GLN E 1 92 ? -32.137 51.791 -32.844 1.00 60.19 ? 73 GLN E NE2 1 ATOM 7019 N N . VAL E 1 93 ? -27.898 54.182 -30.397 1.00 23.03 ? 74 VAL E N 1 ATOM 7020 C CA . VAL E 1 93 ? -26.748 53.919 -31.250 1.00 18.74 ? 74 VAL E CA 1 ATOM 7021 C C . VAL E 1 93 ? -26.107 52.593 -30.833 1.00 17.40 ? 74 VAL E C 1 ATOM 7022 O O . VAL E 1 93 ? -26.344 52.117 -29.717 1.00 14.87 ? 74 VAL E O 1 ATOM 7023 C CB . VAL E 1 93 ? -25.681 55.053 -31.181 1.00 20.21 ? 74 VAL E CB 1 ATOM 7024 C CG1 . VAL E 1 93 ? -26.179 56.321 -31.833 1.00 27.23 ? 74 VAL E CG1 1 ATOM 7025 C CG2 . VAL E 1 93 ? -25.286 55.328 -29.745 1.00 15.75 ? 74 VAL E CG2 1 ATOM 7026 N N . SER E 1 94 ? -25.304 52.006 -31.727 1.00 15.08 ? 75 SER E N 1 ATOM 7027 C CA . SER E 1 94 ? -24.520 50.822 -31.405 1.00 13.83 ? 75 SER E CA 1 ATOM 7028 C C . SER E 1 94 ? -23.080 51.231 -31.194 1.00 16.11 ? 75 SER E C 1 ATOM 7029 O O . SER E 1 94 ? -22.521 51.998 -31.979 1.00 17.46 ? 75 SER E O 1 ATOM 7030 C CB . SER E 1 94 ? -24.623 49.776 -32.508 1.00 20.25 ? 75 SER E CB 1 ATOM 7031 O OG . SER E 1 94 ? -25.868 49.100 -32.426 1.00 35.67 ? 75 SER E OG 1 ATOM 7032 N N . VAL E 1 95 ? -22.476 50.727 -30.125 1.00 15.83 ? 76 VAL E N 1 ATOM 7033 C CA . VAL E 1 95 ? -21.154 51.185 -29.715 1.00 13.17 ? 76 VAL E CA 1 ATOM 7034 C C . VAL E 1 95 ? -20.242 49.990 -29.471 1.00 13.48 ? 76 VAL E C 1 ATOM 7035 O O . VAL E 1 95 ? -20.612 49.049 -28.763 1.00 13.98 ? 76 VAL E O 1 ATOM 7036 C CB . VAL E 1 95 ? -21.249 51.993 -28.415 1.00 11.11 ? 76 VAL E CB 1 ATOM 7037 C CG1 . VAL E 1 95 ? -19.860 52.453 -27.972 1.00 11.36 ? 76 VAL E CG1 1 ATOM 7038 C CG2 . VAL E 1 95 ? -22.221 53.144 -28.559 1.00 11.93 ? 76 VAL E CG2 1 ATOM 7039 N N . PRO E 1 96 ? -19.033 50.024 -30.036 1.00 13.65 ? 77 PRO E N 1 ATOM 7040 C CA . PRO E 1 96 ? -18.092 48.926 -29.748 1.00 15.26 ? 77 PRO E CA 1 ATOM 7041 C C . PRO E 1 96 ? -17.796 48.890 -28.253 1.00 15.47 ? 77 PRO E C 1 ATOM 7042 O O . PRO E 1 96 ? -17.536 49.960 -27.689 1.00 16.42 ? 77 PRO E O 1 ATOM 7043 C CB . PRO E 1 96 ? -16.828 49.328 -30.523 1.00 11.56 ? 77 PRO E CB 1 ATOM 7044 C CG . PRO E 1 96 ? -17.305 50.306 -31.550 1.00 12.03 ? 77 PRO E CG 1 ATOM 7045 C CD . PRO E 1 96 ? -18.447 51.055 -30.907 1.00 13.80 ? 77 PRO E CD 1 ATOM 7046 N N . ILE E 1 97 ? -17.834 47.709 -27.625 1.00 17.71 ? 78 ILE E N 1 ATOM 7047 C CA . ILE E 1 97 ? -17.675 47.618 -26.160 1.00 16.34 ? 78 ILE E CA 1 ATOM 7048 C C . ILE E 1 97 ? -16.314 48.110 -25.674 1.00 15.24 ? 78 ILE E C 1 ATOM 7049 O O . ILE E 1 97 ? -16.146 48.432 -24.504 1.00 18.68 ? 78 ILE E O 1 ATOM 7050 C CB . ILE E 1 97 ? -17.921 46.214 -25.599 1.00 13.26 ? 78 ILE E CB 1 ATOM 7051 C CG1 . ILE E 1 97 ? -16.930 45.215 -26.200 1.00 16.62 ? 78 ILE E CG1 1 ATOM 7052 C CG2 . ILE E 1 97 ? -19.381 45.792 -25.789 1.00 12.49 ? 78 ILE E CG2 1 ATOM 7053 C CD1 . ILE E 1 97 ? -16.939 43.858 -25.480 1.00 18.64 ? 78 ILE E CD1 1 ATOM 7054 N N . SER E 1 98 ? -15.341 48.170 -26.568 1.00 13.15 ? 79 SER E N 1 ATOM 7055 C CA . SER E 1 98 ? -14.057 48.727 -26.194 1.00 14.97 ? 79 SER E CA 1 ATOM 7056 C C . SER E 1 98 ? -14.148 50.211 -25.770 1.00 20.95 ? 79 SER E C 1 ATOM 7057 O O . SER E 1 98 ? -13.271 50.703 -25.060 1.00 21.50 ? 79 SER E O 1 ATOM 7058 C CB . SER E 1 98 ? -13.046 48.530 -27.320 1.00 21.50 ? 79 SER E CB 1 ATOM 7059 O OG . SER E 1 98 ? -13.349 49.350 -28.439 1.00 31.87 ? 79 SER E OG 1 ATOM 7060 N N . SER E 1 99 ? -15.208 50.914 -26.179 1.00 18.40 ? 80 SER E N 1 ATOM 7061 C CA . SER E 1 99 ? -15.385 52.324 -25.800 1.00 14.30 ? 80 SER E CA 1 ATOM 7062 C C . SER E 1 99 ? -16.361 52.552 -24.654 1.00 14.88 ? 80 SER E C 1 ATOM 7063 O O . SER E 1 99 ? -16.867 53.640 -24.521 1.00 19.44 ? 80 SER E O 1 ATOM 7064 C CB . SER E 1 99 ? -15.881 53.147 -26.990 1.00 15.06 ? 80 SER E CB 1 ATOM 7065 O OG . SER E 1 99 ? -15.142 52.843 -28.154 1.00 26.95 ? 80 SER E OG 1 ATOM 7066 N N . LEU E 1 100 ? -16.650 51.537 -23.851 1.00 17.00 ? 81 LEU E N 1 ATOM 7067 C CA . LEU E 1 100 ? -17.634 51.652 -22.773 1.00 16.71 ? 81 LEU E CA 1 ATOM 7068 C C . LEU E 1 100 ? -17.151 50.938 -21.541 1.00 16.48 ? 81 LEU E C 1 ATOM 7069 O O . LEU E 1 100 ? -16.444 49.928 -21.642 1.00 17.66 ? 81 LEU E O 1 ATOM 7070 C CB . LEU E 1 100 ? -18.903 50.902 -23.148 1.00 21.99 ? 81 LEU E CB 1 ATOM 7071 C CG . LEU E 1 100 ? -19.756 51.435 -24.263 1.00 20.44 ? 81 LEU E CG 1 ATOM 7072 C CD1 . LEU E 1 100 ? -20.955 50.550 -24.347 1.00 16.58 ? 81 LEU E CD1 1 ATOM 7073 C CD2 . LEU E 1 100 ? -20.147 52.856 -23.904 1.00 26.68 ? 81 LEU E CD2 1 ATOM 7074 N N . TRP E 1 101 ? -17.577 51.396 -20.373 1.00 15.19 ? 82 TRP E N 1 ATOM 7075 C CA . TRP E 1 101 ? -17.387 50.563 -19.197 1.00 15.06 ? 82 TRP E CA 1 ATOM 7076 C C . TRP E 1 101 ? -18.323 49.376 -19.326 1.00 16.80 ? 82 TRP E C 1 ATOM 7077 O O . TRP E 1 101 ? -19.443 49.505 -19.810 1.00 15.52 ? 82 TRP E O 1 ATOM 7078 C CB . TRP E 1 101 ? -17.685 51.313 -17.908 1.00 15.12 ? 82 TRP E CB 1 ATOM 7079 C CG . TRP E 1 101 ? -17.570 50.420 -16.728 1.00 13.87 ? 82 TRP E CG 1 ATOM 7080 C CD1 . TRP E 1 101 ? -16.441 50.142 -16.014 1.00 15.47 ? 82 TRP E CD1 1 ATOM 7081 C CD2 . TRP E 1 101 ? -18.620 49.680 -16.120 1.00 13.73 ? 82 TRP E CD2 1 ATOM 7082 N NE1 . TRP E 1 101 ? -16.729 49.282 -14.989 1.00 15.06 ? 82 TRP E NE1 1 ATOM 7083 C CE2 . TRP E 1 101 ? -18.070 48.975 -15.032 1.00 16.32 ? 82 TRP E CE2 1 ATOM 7084 C CE3 . TRP E 1 101 ? -19.992 49.544 -16.385 1.00 15.22 ? 82 TRP E CE3 1 ATOM 7085 C CZ2 . TRP E 1 101 ? -18.830 48.131 -14.207 1.00 16.96 ? 82 TRP E CZ2 1 ATOM 7086 C CZ3 . TRP E 1 101 ? -20.757 48.711 -15.566 1.00 14.49 ? 82 TRP E CZ3 1 ATOM 7087 C CH2 . TRP E 1 101 ? -20.169 48.012 -14.490 1.00 15.86 ? 82 TRP E CH2 1 ATOM 7088 N N . VAL E 1 102 ? -17.850 48.216 -18.891 1.00 21.37 ? 83 VAL E N 1 ATOM 7089 C CA . VAL E 1 102 ? -18.610 46.968 -18.962 1.00 16.35 ? 83 VAL E CA 1 ATOM 7090 C C . VAL E 1 102 ? -18.376 46.225 -17.644 1.00 18.93 ? 83 VAL E C 1 ATOM 7091 O O . VAL E 1 102 ? -17.246 46.204 -17.134 1.00 17.48 ? 83 VAL E O 1 ATOM 7092 C CB . VAL E 1 102 ? -18.140 46.118 -20.159 1.00 12.16 ? 83 VAL E CB 1 ATOM 7093 C CG1 . VAL E 1 102 ? -18.403 44.647 -19.912 1.00 25.92 ? 83 VAL E CG1 1 ATOM 7094 C CG2 . VAL E 1 102 ? -18.810 46.577 -21.422 1.00 11.05 ? 83 VAL E CG2 1 ATOM 7095 N N . PRO E 1 103 ? -19.439 45.630 -17.072 1.00 17.40 ? 84 PRO E N 1 ATOM 7096 C CA . PRO E 1 103 ? -19.267 44.874 -15.819 1.00 16.16 ? 84 PRO E CA 1 ATOM 7097 C C . PRO E 1 103 ? -18.359 43.629 -15.990 1.00 18.06 ? 84 PRO E C 1 ATOM 7098 O O . PRO E 1 103 ? -18.420 42.957 -17.033 1.00 18.68 ? 84 PRO E O 1 ATOM 7099 C CB . PRO E 1 103 ? -20.701 44.474 -15.445 1.00 15.29 ? 84 PRO E CB 1 ATOM 7100 C CG . PRO E 1 103 ? -21.458 44.493 -16.744 1.00 16.73 ? 84 PRO E CG 1 ATOM 7101 C CD . PRO E 1 103 ? -20.819 45.576 -17.592 1.00 16.74 ? 84 PRO E CD 1 ATOM 7102 N N . ASP E 1 104 ? -17.526 43.350 -14.981 1.00 18.03 ? 85 ASP E N 1 ATOM 7103 C CA . ASP E 1 104 ? -16.553 42.243 -15.017 1.00 19.02 ? 85 ASP E CA 1 ATOM 7104 C C . ASP E 1 104 ? -17.148 40.915 -14.549 1.00 22.44 ? 85 ASP E C 1 ATOM 7105 O O . ASP E 1 104 ? -16.660 40.295 -13.595 1.00 22.40 ? 85 ASP E O 1 ATOM 7106 C CB . ASP E 1 104 ? -15.288 42.570 -14.192 1.00 18.30 ? 85 ASP E CB 1 ATOM 7107 C CG . ASP E 1 104 ? -15.587 42.832 -12.699 1.00 22.03 ? 85 ASP E CG 1 ATOM 7108 O OD1 . ASP E 1 104 ? -16.701 43.281 -12.342 1.00 21.58 ? 85 ASP E OD1 1 ATOM 7109 O OD2 . ASP E 1 104 ? -14.689 42.593 -11.869 1.00 23.72 ? 85 ASP E OD2 1 ATOM 7110 N N . LEU E 1 105 ? -18.200 40.470 -15.232 1.00 22.36 ? 86 LEU E N 1 ATOM 7111 C CA . LEU E 1 105 ? -18.868 39.230 -14.874 1.00 17.15 ? 86 LEU E CA 1 ATOM 7112 C C . LEU E 1 105 ? -18.031 38.021 -15.292 1.00 16.22 ? 86 LEU E C 1 ATOM 7113 O O . LEU E 1 105 ? -17.312 38.065 -16.293 1.00 15.30 ? 86 LEU E O 1 ATOM 7114 C CB . LEU E 1 105 ? -20.245 39.193 -15.521 1.00 18.07 ? 86 LEU E CB 1 ATOM 7115 C CG . LEU E 1 105 ? -21.129 40.387 -15.138 1.00 17.38 ? 86 LEU E CG 1 ATOM 7116 C CD1 . LEU E 1 105 ? -22.463 40.374 -15.911 1.00 16.84 ? 86 LEU E CD1 1 ATOM 7117 C CD2 . LEU E 1 105 ? -21.392 40.422 -13.624 1.00 16.14 ? 86 LEU E CD2 1 ATOM 7118 N N . ALA E 1 106 ? -18.102 36.958 -14.494 1.00 20.49 ? 87 ALA E N 1 ATOM 7119 C CA . ALA E 1 106 ? -17.439 35.680 -14.808 1.00 17.67 ? 87 ALA E CA 1 ATOM 7120 C C . ALA E 1 106 ? -18.300 34.526 -14.318 1.00 18.62 ? 87 ALA E C 1 ATOM 7121 O O . ALA E 1 106 ? -19.061 34.658 -13.355 1.00 21.41 ? 87 ALA E O 1 ATOM 7122 C CB . ALA E 1 106 ? -16.049 35.614 -14.178 1.00 13.22 ? 87 ALA E CB 1 ATOM 7123 N N . ALA E 1 107 ? -18.182 33.393 -14.992 1.00 16.65 ? 88 ALA E N 1 ATOM 7124 C CA . ALA E 1 107 ? -18.836 32.166 -14.553 1.00 16.24 ? 88 ALA E CA 1 ATOM 7125 C C . ALA E 1 107 ? -17.901 31.361 -13.608 1.00 17.05 ? 88 ALA E C 1 ATOM 7126 O O . ALA E 1 107 ? -16.844 30.849 -14.025 1.00 14.66 ? 88 ALA E O 1 ATOM 7127 C CB . ALA E 1 107 ? -19.245 31.347 -15.770 1.00 13.64 ? 88 ALA E CB 1 ATOM 7128 N N . TYR E 1 108 ? -18.289 31.254 -12.338 1.00 17.15 ? 89 TYR E N 1 ATOM 7129 C CA . TYR E 1 108 ? -17.427 30.643 -11.327 1.00 13.15 ? 89 TYR E CA 1 ATOM 7130 C C . TYR E 1 108 ? -17.111 29.166 -11.606 1.00 11.97 ? 89 TYR E C 1 ATOM 7131 O O . TYR E 1 108 ? -16.053 28.663 -11.248 1.00 13.03 ? 89 TYR E O 1 ATOM 7132 C CB . TYR E 1 108 ? -18.044 30.802 -9.945 1.00 14.87 ? 89 TYR E CB 1 ATOM 7133 C CG . TYR E 1 108 ? -17.828 32.155 -9.330 1.00 21.11 ? 89 TYR E CG 1 ATOM 7134 C CD1 . TYR E 1 108 ? -18.520 33.270 -9.782 1.00 28.19 ? 89 TYR E CD1 1 ATOM 7135 C CD2 . TYR E 1 108 ? -16.939 32.321 -8.285 1.00 26.71 ? 89 TYR E CD2 1 ATOM 7136 C CE1 . TYR E 1 108 ? -18.322 34.520 -9.209 1.00 27.94 ? 89 TYR E CE1 1 ATOM 7137 C CE2 . TYR E 1 108 ? -16.725 33.559 -7.706 1.00 26.30 ? 89 TYR E CE2 1 ATOM 7138 C CZ . TYR E 1 108 ? -17.420 34.655 -8.169 1.00 32.03 ? 89 TYR E CZ 1 ATOM 7139 O OH . TYR E 1 108 ? -17.217 35.890 -7.587 1.00 36.81 ? 89 TYR E OH 1 ATOM 7140 N N . ASN E 1 109 ? -18.020 28.460 -12.252 1.00 16.89 ? 90 ASN E N 1 ATOM 7141 C CA . ASN E 1 109 ? -17.785 27.040 -12.529 1.00 20.54 ? 90 ASN E CA 1 ATOM 7142 C C . ASN E 1 109 ? -17.517 26.763 -14.008 1.00 22.01 ? 90 ASN E C 1 ATOM 7143 O O . ASN E 1 109 ? -17.748 25.659 -14.507 1.00 22.77 ? 90 ASN E O 1 ATOM 7144 C CB . ASN E 1 109 ? -18.924 26.153 -11.985 1.00 16.53 ? 90 ASN E CB 1 ATOM 7145 C CG . ASN E 1 109 ? -20.290 26.516 -12.556 1.00 19.68 ? 90 ASN E CG 1 ATOM 7146 O OD1 . ASN E 1 109 ? -20.703 27.693 -12.583 1.00 21.99 ? 90 ASN E OD1 1 ATOM 7147 N ND2 . ASN E 1 109 ? -21.004 25.499 -13.015 1.00 22.38 ? 90 ASN E ND2 1 ATOM 7148 N N . ALA E 1 110 ? -17.041 27.784 -14.718 1.00 21.27 ? 91 ALA E N 1 ATOM 7149 C CA . ALA E 1 110 ? -16.599 27.589 -16.102 1.00 24.27 ? 91 ALA E CA 1 ATOM 7150 C C . ALA E 1 110 ? -15.233 26.893 -16.098 1.00 21.88 ? 91 ALA E C 1 ATOM 7151 O O . ALA E 1 110 ? -14.433 27.074 -15.170 1.00 29.37 ? 91 ALA E O 1 ATOM 7152 C CB . ALA E 1 110 ? -16.541 28.908 -16.838 1.00 18.58 ? 91 ALA E CB 1 ATOM 7153 N N . ILE E 1 111 ? -14.965 26.068 -17.100 1.00 22.26 ? 92 ILE E N 1 ATOM 7154 C CA . ILE E 1 111 ? -13.665 25.394 -17.148 1.00 26.42 ? 92 ILE E CA 1 ATOM 7155 C C . ILE E 1 111 ? -12.946 25.711 -18.451 1.00 20.92 ? 92 ILE E C 1 ATOM 7156 O O . ILE E 1 111 ? -11.955 25.084 -18.805 1.00 26.62 ? 92 ILE E O 1 ATOM 7157 C CB . ILE E 1 111 ? -13.760 23.855 -16.909 1.00 24.70 ? 92 ILE E CB 1 ATOM 7158 C CG1 . ILE E 1 111 ? -14.783 23.216 -17.840 1.00 25.49 ? 92 ILE E CG1 1 ATOM 7159 C CG2 . ILE E 1 111 ? -14.118 23.550 -15.462 1.00 23.51 ? 92 ILE E CG2 1 ATOM 7160 C CD1 . ILE E 1 111 ? -14.836 21.713 -17.715 1.00 29.60 ? 92 ILE E CD1 1 ATOM 7161 N N . SER E 1 112 ? -13.472 26.691 -19.166 1.00 18.38 ? 93 SER E N 1 ATOM 7162 C CA . SER E 1 112 ? -12.866 27.173 -20.399 1.00 20.05 ? 93 SER E CA 1 ATOM 7163 C C . SER E 1 112 ? -13.219 28.646 -20.466 1.00 22.93 ? 93 SER E C 1 ATOM 7164 O O . SER E 1 112 ? -14.200 29.078 -19.851 1.00 21.51 ? 93 SER E O 1 ATOM 7165 C CB . SER E 1 112 ? -13.443 26.442 -21.611 1.00 21.05 ? 93 SER E CB 1 ATOM 7166 O OG . SER E 1 112 ? -14.810 26.770 -21.832 1.00 21.96 ? 93 SER E OG 1 ATOM 7167 N N . LYS E 1 113 ? -12.452 29.430 -21.212 1.00 22.82 ? 94 LYS E N 1 ATOM 7168 C CA . LYS E 1 113 ? -12.821 30.843 -21.339 1.00 22.95 ? 94 LYS E CA 1 ATOM 7169 C C . LYS E 1 113 ? -14.005 31.039 -22.290 1.00 20.00 ? 94 LYS E C 1 ATOM 7170 O O . LYS E 1 113 ? -14.240 30.211 -23.177 1.00 22.12 ? 94 LYS E O 1 ATOM 7171 C CB . LYS E 1 113 ? -11.618 31.710 -21.722 1.00 24.78 ? 94 LYS E CB 1 ATOM 7172 C CG . LYS E 1 113 ? -11.004 31.416 -23.073 1.00 29.50 ? 94 LYS E CG 1 ATOM 7173 C CD . LYS E 1 113 ? -9.676 32.180 -23.203 1.00 43.71 ? 94 LYS E CD 1 ATOM 7174 C CE . LYS E 1 113 ? -9.821 33.671 -22.781 1.00 45.47 ? 94 LYS E CE 1 ATOM 7175 N NZ . LYS E 1 113 ? -8.629 34.509 -23.135 1.00 39.55 ? 94 LYS E NZ 1 ATOM 7176 N N . PRO E 1 114 ? -14.773 32.122 -22.093 1.00 19.78 ? 95 PRO E N 1 ATOM 7177 C CA . PRO E 1 114 ? -15.927 32.321 -22.972 1.00 22.43 ? 95 PRO E CA 1 ATOM 7178 C C . PRO E 1 114 ? -15.469 32.487 -24.417 1.00 19.03 ? 95 PRO E C 1 ATOM 7179 O O . PRO E 1 114 ? -14.532 33.237 -24.669 1.00 16.83 ? 95 PRO E O 1 ATOM 7180 C CB . PRO E 1 114 ? -16.524 33.642 -22.471 1.00 19.95 ? 95 PRO E CB 1 ATOM 7181 C CG . PRO E 1 114 ? -15.964 33.850 -21.123 1.00 16.13 ? 95 PRO E CG 1 ATOM 7182 C CD . PRO E 1 114 ? -14.622 33.220 -21.125 1.00 18.47 ? 95 PRO E CD 1 ATOM 7183 N N . GLU E 1 115 ? -16.105 31.776 -25.340 1.00 21.46 ? 96 GLU E N 1 ATOM 7184 C CA . GLU E 1 115 ? -15.863 31.969 -26.768 1.00 23.34 ? 96 GLU E CA 1 ATOM 7185 C C . GLU E 1 115 ? -17.002 32.838 -27.305 1.00 23.02 ? 96 GLU E C 1 ATOM 7186 O O . GLU E 1 115 ? -18.159 32.376 -27.397 1.00 20.43 ? 96 GLU E O 1 ATOM 7187 C CB . GLU E 1 115 ? -15.850 30.616 -27.480 1.00 25.66 ? 96 GLU E CB 1 ATOM 7188 C CG . GLU E 1 115 ? -15.442 30.646 -28.950 1.00 39.53 ? 96 GLU E CG 1 ATOM 7189 C CD . GLU E 1 115 ? -15.414 29.230 -29.561 1.00 60.91 ? 96 GLU E CD 1 ATOM 7190 O OE1 . GLU E 1 115 ? -15.390 28.258 -28.754 1.00 58.11 ? 96 GLU E OE1 1 ATOM 7191 O OE2 . GLU E 1 115 ? -15.427 29.089 -30.828 1.00 48.97 ? 96 GLU E OE2 1 ATOM 7192 N N . VAL E 1 116 ? -16.694 34.095 -27.639 1.00 17.61 ? 97 VAL E N 1 ATOM 7193 C CA . VAL E 1 116 ? -17.740 35.025 -28.093 1.00 18.06 ? 97 VAL E CA 1 ATOM 7194 C C . VAL E 1 116 ? -18.041 34.874 -29.582 1.00 17.13 ? 97 VAL E C 1 ATOM 7195 O O . VAL E 1 116 ? -17.187 35.134 -30.422 1.00 24.70 ? 97 VAL E O 1 ATOM 7196 C CB . VAL E 1 116 ? -17.392 36.479 -27.738 1.00 15.47 ? 97 VAL E CB 1 ATOM 7197 C CG1 . VAL E 1 116 ? -18.499 37.411 -28.157 1.00 19.36 ? 97 VAL E CG1 1 ATOM 7198 C CG2 . VAL E 1 116 ? -17.184 36.585 -26.267 1.00 8.06 ? 97 VAL E CG2 1 ATOM 7199 N N . LEU E 1 117 ? -19.263 34.463 -29.897 1.00 14.46 ? 98 LEU E N 1 ATOM 7200 C CA . LEU E 1 117 ? -19.637 34.115 -31.265 1.00 16.91 ? 98 LEU E CA 1 ATOM 7201 C C . LEU E 1 117 ? -20.049 35.308 -32.133 1.00 19.52 ? 98 LEU E C 1 ATOM 7202 O O . LEU E 1 117 ? -19.944 35.254 -33.360 1.00 20.25 ? 98 LEU E O 1 ATOM 7203 C CB . LEU E 1 117 ? -20.761 33.074 -31.238 1.00 16.99 ? 98 LEU E CB 1 ATOM 7204 C CG . LEU E 1 117 ? -20.422 31.750 -30.534 1.00 19.83 ? 98 LEU E CG 1 ATOM 7205 C CD1 . LEU E 1 117 ? -21.588 30.769 -30.558 1.00 17.90 ? 98 LEU E CD1 1 ATOM 7206 C CD2 . LEU E 1 117 ? -19.154 31.100 -31.096 1.00 22.27 ? 98 LEU E CD2 1 ATOM 7207 N N . THR E 1 118 ? -20.503 36.383 -31.490 1.00 16.54 ? 99 THR E N 1 ATOM 7208 C CA . THR E 1 118 ? -21.142 37.498 -32.194 1.00 17.73 ? 99 THR E CA 1 ATOM 7209 C C . THR E 1 118 ? -20.297 38.753 -32.163 1.00 20.57 ? 99 THR E C 1 ATOM 7210 O O . THR E 1 118 ? -19.364 38.827 -31.368 1.00 28.36 ? 99 THR E O 1 ATOM 7211 C CB . THR E 1 118 ? -22.477 37.800 -31.554 1.00 22.21 ? 99 THR E CB 1 ATOM 7212 O OG1 . THR E 1 118 ? -22.293 37.938 -30.132 1.00 29.34 ? 99 THR E OG1 1 ATOM 7213 C CG2 . THR E 1 118 ? -23.454 36.661 -31.852 1.00 19.34 ? 99 THR E CG2 1 ATOM 7214 N N . PRO E 1 119 ? -20.606 39.736 -33.031 1.00 17.36 ? 100 PRO E N 1 ATOM 7215 C CA . PRO E 1 119 ? -19.956 41.060 -33.011 1.00 26.23 ? 100 PRO E CA 1 ATOM 7216 C C . PRO E 1 119 ? -19.985 41.680 -31.617 1.00 25.52 ? 100 PRO E C 1 ATOM 7217 O O . PRO E 1 119 ? -21.002 41.540 -30.931 1.00 28.71 ? 100 PRO E O 1 ATOM 7218 C CB . PRO E 1 119 ? -20.840 41.893 -33.938 1.00 22.61 ? 100 PRO E CB 1 ATOM 7219 C CG . PRO E 1 119 ? -21.334 40.888 -34.952 1.00 25.21 ? 100 PRO E CG 1 ATOM 7220 C CD . PRO E 1 119 ? -21.493 39.578 -34.197 1.00 22.25 ? 100 PRO E CD 1 ATOM 7221 N N . GLN E 1 120 ? -18.906 42.333 -31.194 1.00 18.52 ? 101 GLN E N 1 ATOM 7222 C CA . GLN E 1 120 ? -18.877 42.856 -29.834 1.00 22.14 ? 101 GLN E CA 1 ATOM 7223 C C . GLN E 1 120 ? -19.388 44.310 -29.685 1.00 19.04 ? 101 GLN E C 1 ATOM 7224 O O . GLN E 1 120 ? -18.653 45.211 -29.288 1.00 15.98 ? 101 GLN E O 1 ATOM 7225 C CB . GLN E 1 120 ? -17.507 42.626 -29.215 1.00 19.06 ? 101 GLN E CB 1 ATOM 7226 C CG . GLN E 1 120 ? -17.269 41.156 -28.910 1.00 24.91 ? 101 GLN E CG 1 ATOM 7227 C CD . GLN E 1 120 ? -15.856 40.846 -28.417 1.00 33.53 ? 101 GLN E CD 1 ATOM 7228 O OE1 . GLN E 1 120 ? -15.288 41.595 -27.623 1.00 53.53 ? 101 GLN E OE1 1 ATOM 7229 N NE2 . GLN E 1 120 ? -15.281 39.734 -28.895 1.00 29.74 ? 101 GLN E NE2 1 ATOM 7230 N N . LEU E 1 121 ? -20.670 44.501 -30.002 1.00 17.81 ? 102 LEU E N 1 ATOM 7231 C CA . LEU E 1 121 ? -21.331 45.799 -29.921 1.00 14.58 ? 102 LEU E CA 1 ATOM 7232 C C . LEU E 1 121 ? -22.382 45.848 -28.813 1.00 15.57 ? 102 LEU E C 1 ATOM 7233 O O . LEU E 1 121 ? -23.052 44.847 -28.543 1.00 19.56 ? 102 LEU E O 1 ATOM 7234 C CB . LEU E 1 121 ? -22.008 46.124 -31.247 1.00 13.39 ? 102 LEU E CB 1 ATOM 7235 C CG . LEU E 1 121 ? -21.058 46.143 -32.441 1.00 15.24 ? 102 LEU E CG 1 ATOM 7236 C CD1 . LEU E 1 121 ? -21.799 46.440 -33.738 1.00 16.89 ? 102 LEU E CD1 1 ATOM 7237 C CD2 . LEU E 1 121 ? -19.971 47.160 -32.199 1.00 13.65 ? 102 LEU E CD2 1 ATOM 7238 N N . ALA E 1 122 ? -22.521 47.012 -28.176 1.00 15.23 ? 103 ALA E N 1 ATOM 7239 C CA . ALA E 1 122 ? -23.549 47.229 -27.157 1.00 16.15 ? 103 ALA E CA 1 ATOM 7240 C C . ALA E 1 122 ? -24.583 48.207 -27.683 1.00 13.85 ? 103 ALA E C 1 ATOM 7241 O O . ALA E 1 122 ? -24.282 49.063 -28.508 1.00 16.77 ? 103 ALA E O 1 ATOM 7242 C CB . ALA E 1 122 ? -22.937 47.755 -25.861 1.00 14.84 ? 103 ALA E CB 1 ATOM 7243 N N . HIS E 1 123 ? -25.803 48.079 -27.190 1.00 12.57 ? 104 HIS E N 1 ATOM 7244 C CA . HIS E 1 123 ? -26.886 48.963 -27.571 1.00 15.95 ? 104 HIS E CA 1 ATOM 7245 C C . HIS E 1 123 ? -26.988 50.069 -26.523 1.00 23.58 ? 104 HIS E C 1 ATOM 7246 O O . HIS E 1 123 ? -27.039 49.782 -25.317 1.00 25.78 ? 104 HIS E O 1 ATOM 7247 C CB . HIS E 1 123 ? -28.171 48.157 -27.616 1.00 20.20 ? 104 HIS E CB 1 ATOM 7248 C CG . HIS E 1 123 ? -29.302 48.850 -28.303 1.00 22.82 ? 104 HIS E CG 1 ATOM 7249 N ND1 . HIS E 1 123 ? -30.369 49.384 -27.613 1.00 26.04 ? 104 HIS E ND1 1 ATOM 7250 C CD2 . HIS E 1 123 ? -29.557 49.054 -29.613 1.00 26.49 ? 104 HIS E CD2 1 ATOM 7251 C CE1 . HIS E 1 123 ? -31.222 49.914 -28.471 1.00 30.01 ? 104 HIS E CE1 1 ATOM 7252 N NE2 . HIS E 1 123 ? -30.755 49.728 -29.690 1.00 34.99 ? 104 HIS E NE2 1 ATOM 7253 N N . VAL E 1 124 ? -26.998 51.328 -26.965 1.00 19.27 ? 105 VAL E N 1 ATOM 7254 C CA . VAL E 1 124 ? -27.079 52.453 -26.038 1.00 16.99 ? 105 VAL E CA 1 ATOM 7255 C C . VAL E 1 124 ? -28.267 53.340 -26.386 1.00 22.00 ? 105 VAL E C 1 ATOM 7256 O O . VAL E 1 124 ? -28.417 53.782 -27.520 1.00 22.55 ? 105 VAL E O 1 ATOM 7257 C CB . VAL E 1 124 ? -25.797 53.338 -26.070 1.00 20.96 ? 105 VAL E CB 1 ATOM 7258 C CG1 . VAL E 1 124 ? -25.818 54.405 -24.935 1.00 16.45 ? 105 VAL E CG1 1 ATOM 7259 C CG2 . VAL E 1 124 ? -24.538 52.505 -25.996 1.00 18.32 ? 105 VAL E CG2 1 ATOM 7260 N N . VAL E 1 125 ? -29.095 53.617 -25.390 1.00 24.51 ? 106 VAL E N 1 ATOM 7261 C CA . VAL E 1 125 ? -30.274 54.462 -25.551 1.00 24.27 ? 106 VAL E CA 1 ATOM 7262 C C . VAL E 1 125 ? -29.952 55.834 -24.969 1.00 26.26 ? 106 VAL E C 1 ATOM 7263 O O . VAL E 1 125 ? -29.140 55.924 -24.048 1.00 31.12 ? 106 VAL E O 1 ATOM 7264 C CB . VAL E 1 125 ? -31.475 53.822 -24.817 1.00 24.05 ? 106 VAL E CB 1 ATOM 7265 C CG1 . VAL E 1 125 ? -32.653 54.767 -24.763 1.00 28.24 ? 106 VAL E CG1 1 ATOM 7266 C CG2 . VAL E 1 125 ? -31.861 52.511 -25.496 1.00 20.69 ? 106 VAL E CG2 1 ATOM 7267 N N . SER E 1 126 ? -30.569 56.893 -25.493 1.00 27.05 ? 107 SER E N 1 ATOM 7268 C CA . SER E 1 126 ? -30.223 58.265 -25.085 1.00 31.91 ? 107 SER E CA 1 ATOM 7269 C C . SER E 1 126 ? -30.276 58.550 -23.578 1.00 27.94 ? 107 SER E C 1 ATOM 7270 O O . SER E 1 126 ? -29.595 59.462 -23.103 1.00 25.70 ? 107 SER E O 1 ATOM 7271 C CB . SER E 1 126 ? -31.067 59.293 -25.836 1.00 31.19 ? 107 SER E CB 1 ATOM 7272 O OG . SER E 1 126 ? -32.436 59.013 -25.660 1.00 45.08 ? 107 SER E OG 1 ATOM 7273 N N . ASP E 1 127 ? -31.070 57.787 -22.830 1.00 23.20 ? 108 ASP E N 1 ATOM 7274 C CA . ASP E 1 127 ? -31.116 58.002 -21.384 1.00 25.99 ? 108 ASP E CA 1 ATOM 7275 C C . ASP E 1 127 ? -29.873 57.486 -20.633 1.00 27.95 ? 108 ASP E C 1 ATOM 7276 O O . ASP E 1 127 ? -29.646 57.833 -19.474 1.00 32.28 ? 108 ASP E O 1 ATOM 7277 C CB . ASP E 1 127 ? -32.414 57.447 -20.764 1.00 27.64 ? 108 ASP E CB 1 ATOM 7278 C CG . ASP E 1 127 ? -32.582 55.942 -20.963 1.00 39.88 ? 108 ASP E CG 1 ATOM 7279 O OD1 . ASP E 1 127 ? -31.606 55.263 -21.365 1.00 45.91 ? 108 ASP E OD1 1 ATOM 7280 O OD2 . ASP E 1 127 ? -33.700 55.428 -20.699 1.00 45.81 ? 108 ASP E OD2 1 ATOM 7281 N N . GLY E 1 128 ? -29.070 56.662 -21.299 1.00 28.18 ? 109 GLY E N 1 ATOM 7282 C CA . GLY E 1 128 ? -27.894 56.082 -20.681 1.00 26.15 ? 109 GLY E CA 1 ATOM 7283 C C . GLY E 1 128 ? -28.013 54.590 -20.414 1.00 25.95 ? 109 GLY E C 1 ATOM 7284 O O . GLY E 1 128 ? -27.145 53.997 -19.770 1.00 22.34 ? 109 GLY E O 1 ATOM 7285 N N . GLU E 1 129 ? -29.086 53.978 -20.908 1.00 28.01 ? 110 GLU E N 1 ATOM 7286 C CA . GLU E 1 129 ? -29.295 52.542 -20.720 1.00 27.84 ? 110 GLU E CA 1 ATOM 7287 C C . GLU E 1 129 ? -28.488 51.724 -21.711 1.00 23.37 ? 110 GLU E C 1 ATOM 7288 O O . GLU E 1 129 ? -28.539 51.947 -22.912 1.00 21.55 ? 110 GLU E O 1 ATOM 7289 C CB . GLU E 1 129 ? -30.774 52.178 -20.837 1.00 32.30 ? 110 GLU E CB 1 ATOM 7290 C CG . GLU E 1 129 ? -31.551 52.373 -19.541 1.00 47.54 ? 110 GLU E CG 1 ATOM 7291 C CD . GLU E 1 129 ? -31.272 51.266 -18.521 1.00 60.01 ? 110 GLU E CD 1 ATOM 7292 O OE1 . GLU E 1 129 ? -31.263 50.072 -18.927 1.00 59.29 ? 110 GLU E OE1 1 ATOM 7293 O OE2 . GLU E 1 129 ? -31.054 51.592 -17.324 1.00 55.00 ? 110 GLU E OE2 1 ATOM 7294 N N . VAL E 1 130 ? -27.738 50.767 -21.196 1.00 27.11 ? 111 VAL E N 1 ATOM 7295 C CA . VAL E 1 130 ? -26.873 49.959 -22.033 1.00 20.94 ? 111 VAL E CA 1 ATOM 7296 C C . VAL E 1 130 ? -27.334 48.524 -21.973 1.00 22.70 ? 111 VAL E C 1 ATOM 7297 O O . VAL E 1 130 ? -27.697 48.019 -20.897 1.00 21.88 ? 111 VAL E O 1 ATOM 7298 C CB . VAL E 1 130 ? -25.410 50.042 -21.562 1.00 20.26 ? 111 VAL E CB 1 ATOM 7299 C CG1 . VAL E 1 130 ? -24.494 49.313 -22.538 1.00 18.78 ? 111 VAL E CG1 1 ATOM 7300 C CG2 . VAL E 1 130 ? -24.985 51.503 -21.455 1.00 21.62 ? 111 VAL E CG2 1 ATOM 7301 N N . GLN E 1 131 ? -27.349 47.873 -23.135 1.00 21.51 ? 112 GLN E N 1 ATOM 7302 C CA . GLN E 1 131 ? -27.585 46.437 -23.183 1.00 22.38 ? 112 GLN E CA 1 ATOM 7303 C C . GLN E 1 131 ? -26.547 45.742 -24.057 1.00 23.84 ? 112 GLN E C 1 ATOM 7304 O O . GLN E 1 131 ? -26.337 46.117 -25.211 1.00 23.30 ? 112 GLN E O 1 ATOM 7305 C CB . GLN E 1 131 ? -28.995 46.116 -23.659 1.00 20.84 ? 112 GLN E CB 1 ATOM 7306 C CG . GLN E 1 131 ? -29.262 44.618 -23.717 1.00 31.03 ? 112 GLN E CG 1 ATOM 7307 C CD . GLN E 1 131 ? -30.662 44.280 -24.202 1.00 37.47 ? 112 GLN E CD 1 ATOM 7308 O OE1 . GLN E 1 131 ? -31.634 44.961 -23.860 1.00 41.49 ? 112 GLN E OE1 1 ATOM 7309 N NE2 . GLN E 1 131 ? -30.768 43.226 -25.017 1.00 34.00 ? 112 GLN E NE2 1 ATOM 7310 N N . TYR E 1 132 ? -25.886 44.738 -23.491 1.00 21.51 ? 113 TYR E N 1 ATOM 7311 C CA . TYR E 1 132 ? -24.891 43.966 -24.222 1.00 21.97 ? 113 TYR E CA 1 ATOM 7312 C C . TYR E 1 132 ? -25.259 42.481 -24.120 1.00 25.48 ? 113 TYR E C 1 ATOM 7313 O O . TYR E 1 132 ? -25.290 41.905 -23.014 1.00 25.03 ? 113 TYR E O 1 ATOM 7314 C CB . TYR E 1 132 ? -23.488 44.239 -23.660 1.00 22.95 ? 113 TYR E CB 1 ATOM 7315 C CG . TYR E 1 132 ? -22.378 43.404 -24.282 1.00 21.98 ? 113 TYR E CG 1 ATOM 7316 C CD1 . TYR E 1 132 ? -22.276 43.270 -25.661 1.00 17.81 ? 113 TYR E CD1 1 ATOM 7317 C CD2 . TYR E 1 132 ? -21.419 42.769 -23.480 1.00 17.34 ? 113 TYR E CD2 1 ATOM 7318 C CE1 . TYR E 1 132 ? -21.261 42.516 -26.229 1.00 18.87 ? 113 TYR E CE1 1 ATOM 7319 C CE2 . TYR E 1 132 ? -20.399 42.020 -24.034 1.00 15.38 ? 113 TYR E CE2 1 ATOM 7320 C CZ . TYR E 1 132 ? -20.324 41.892 -25.407 1.00 22.04 ? 113 TYR E CZ 1 ATOM 7321 O OH . TYR E 1 132 ? -19.307 41.140 -25.971 1.00 28.97 ? 113 TYR E OH 1 ATOM 7322 N N . THR E 1 133 ? -25.552 41.874 -25.273 1.00 23.05 ? 114 THR E N 1 ATOM 7323 C CA . THR E 1 133 ? -26.056 40.499 -25.332 1.00 18.66 ? 114 THR E CA 1 ATOM 7324 C C . THR E 1 133 ? -25.229 39.657 -26.307 1.00 20.44 ? 114 THR E C 1 ATOM 7325 O O . THR E 1 133 ? -25.654 39.403 -27.436 1.00 24.60 ? 114 THR E O 1 ATOM 7326 C CB . THR E 1 133 ? -27.541 40.468 -25.769 1.00 20.53 ? 114 THR E CB 1 ATOM 7327 O OG1 . THR E 1 133 ? -28.297 41.428 -25.018 1.00 25.40 ? 114 THR E OG1 1 ATOM 7328 C CG2 . THR E 1 133 ? -28.147 39.086 -25.581 1.00 20.64 ? 114 THR E CG2 1 ATOM 7329 N N . PRO E 1 134 ? -24.028 39.229 -25.883 1.00 20.36 ? 115 PRO E N 1 ATOM 7330 C CA . PRO E 1 134 ? -23.235 38.375 -26.781 1.00 18.73 ? 115 PRO E CA 1 ATOM 7331 C C . PRO E 1 134 ? -23.733 36.927 -26.755 1.00 21.89 ? 115 PRO E C 1 ATOM 7332 O O . PRO E 1 134 ? -24.265 36.446 -25.735 1.00 19.08 ? 115 PRO E O 1 ATOM 7333 C CB . PRO E 1 134 ? -21.832 38.458 -26.176 1.00 15.09 ? 115 PRO E CB 1 ATOM 7334 C CG . PRO E 1 134 ? -22.085 38.700 -24.709 1.00 15.23 ? 115 PRO E CG 1 ATOM 7335 C CD . PRO E 1 134 ? -23.310 39.554 -24.633 1.00 16.43 ? 115 PRO E CD 1 ATOM 7336 N N . SER E 1 135 ? -23.563 36.228 -27.870 1.00 19.91 ? 116 SER E N 1 ATOM 7337 C CA . SER E 1 135 ? -23.768 34.782 -27.854 1.00 21.98 ? 116 SER E CA 1 ATOM 7338 C C . SER E 1 135 ? -22.453 34.103 -27.472 1.00 19.31 ? 116 SER E C 1 ATOM 7339 O O . SER E 1 135 ? -21.404 34.389 -28.054 1.00 19.37 ? 116 SER E O 1 ATOM 7340 C CB . SER E 1 135 ? -24.261 34.257 -29.202 1.00 22.23 ? 116 SER E CB 1 ATOM 7341 O OG . SER E 1 135 ? -24.509 32.864 -29.103 1.00 23.63 ? 116 SER E OG 1 ATOM 7342 N N . ILE E 1 136 ? -22.521 33.202 -26.497 1.00 18.09 ? 117 ILE E N 1 ATOM 7343 C CA . ILE E 1 136 ? -21.329 32.571 -25.937 1.00 17.53 ? 117 ILE E CA 1 ATOM 7344 C C . ILE E 1 136 ? -21.400 31.032 -25.940 1.00 17.60 ? 117 ILE E C 1 ATOM 7345 O O . ILE E 1 136 ? -22.395 30.429 -25.517 1.00 17.94 ? 117 ILE E O 1 ATOM 7346 C CB . ILE E 1 136 ? -21.066 33.093 -24.498 1.00 15.11 ? 117 ILE E CB 1 ATOM 7347 C CG1 . ILE E 1 136 ? -20.798 34.599 -24.524 1.00 16.07 ? 117 ILE E CG1 1 ATOM 7348 C CG2 . ILE E 1 136 ? -19.908 32.347 -23.836 1.00 14.38 ? 117 ILE E CG2 1 ATOM 7349 C CD1 . ILE E 1 136 ? -20.710 35.207 -23.143 1.00 20.96 ? 117 ILE E CD1 1 ATOM 7350 N N . ARG E 1 137 ? -20.341 30.397 -26.417 1.00 14.51 ? 118 ARG E N 1 ATOM 7351 C CA . ARG E 1 137 ? -20.157 28.972 -26.188 1.00 15.98 ? 118 ARG E CA 1 ATOM 7352 C C . ARG E 1 137 ? -19.125 28.761 -25.069 1.00 19.36 ? 118 ARG E C 1 ATOM 7353 O O . ARG E 1 137 ? -18.010 29.268 -25.160 1.00 19.18 ? 118 ARG E O 1 ATOM 7354 C CB . ARG E 1 137 ? -19.676 28.281 -27.459 1.00 17.91 ? 118 ARG E CB 1 ATOM 7355 C CG . ARG E 1 137 ? -19.207 26.864 -27.225 1.00 23.05 ? 118 ARG E CG 1 ATOM 7356 C CD . ARG E 1 137 ? -19.158 26.054 -28.498 1.00 24.25 ? 118 ARG E CD 1 ATOM 7357 N NE . ARG E 1 137 ? -18.853 24.648 -28.243 1.00 30.02 ? 118 ARG E NE 1 ATOM 7358 C CZ . ARG E 1 137 ? -18.870 23.684 -29.165 1.00 32.92 ? 118 ARG E CZ 1 ATOM 7359 N NH1 . ARG E 1 137 ? -19.187 23.969 -30.422 1.00 36.82 ? 118 ARG E NH1 1 ATOM 7360 N NH2 . ARG E 1 137 ? -18.585 22.430 -28.828 1.00 31.49 ? 118 ARG E NH2 1 ATOM 7361 N N . GLN E 1 138 ? -19.490 28.010 -24.026 1.00 19.28 ? 119 GLN E N 1 ATOM 7362 C CA . GLN E 1 138 ? -18.602 27.777 -22.870 1.00 17.29 ? 119 GLN E CA 1 ATOM 7363 C C . GLN E 1 138 ? -18.787 26.398 -22.234 1.00 20.34 ? 119 GLN E C 1 ATOM 7364 O O . GLN E 1 138 ? -19.887 25.849 -22.211 1.00 23.01 ? 119 GLN E O 1 ATOM 7365 C CB . GLN E 1 138 ? -18.802 28.857 -21.804 1.00 18.47 ? 119 GLN E CB 1 ATOM 7366 C CG . GLN E 1 138 ? -17.678 28.980 -20.799 1.00 15.42 ? 119 GLN E CG 1 ATOM 7367 C CD . GLN E 1 138 ? -17.703 30.327 -20.065 1.00 19.72 ? 119 GLN E CD 1 ATOM 7368 O OE1 . GLN E 1 138 ? -18.732 31.013 -19.992 1.00 21.40 ? 119 GLN E OE1 1 ATOM 7369 N NE2 . GLN E 1 138 ? -16.554 30.721 -19.543 1.00 23.67 ? 119 GLN E NE2 1 ATOM 7370 N N . ARG E 1 139 ? -17.702 25.847 -21.703 1.00 20.03 ? 120 ARG E N 1 ATOM 7371 C CA . ARG E 1 139 ? -17.749 24.545 -21.060 1.00 21.61 ? 120 ARG E CA 1 ATOM 7372 C C . ARG E 1 139 ? -17.828 24.683 -19.515 1.00 23.37 ? 120 ARG E C 1 ATOM 7373 O O . ARG E 1 139 ? -17.090 25.473 -18.916 1.00 21.96 ? 120 ARG E O 1 ATOM 7374 C CB . ARG E 1 139 ? -16.539 23.716 -21.512 1.00 21.43 ? 120 ARG E CB 1 ATOM 7375 C CG . ARG E 1 139 ? -16.665 22.236 -21.156 1.00 41.20 ? 120 ARG E CG 1 ATOM 7376 C CD . ARG E 1 139 ? -15.789 21.278 -21.998 1.00 42.47 ? 120 ARG E CD 1 ATOM 7377 N NE . ARG E 1 139 ? -16.121 19.877 -21.681 1.00 37.63 ? 120 ARG E NE 1 ATOM 7378 C CZ . ARG E 1 139 ? -17.067 19.171 -22.303 1.00 40.74 ? 120 ARG E CZ 1 ATOM 7379 N NH1 . ARG E 1 139 ? -17.741 19.733 -23.297 1.00 43.84 ? 120 ARG E NH1 1 ATOM 7380 N NH2 . ARG E 1 139 ? -17.338 17.911 -21.947 1.00 36.58 ? 120 ARG E NH2 1 ATOM 7381 N N . PHE E 1 140 ? -18.732 23.942 -18.874 1.00 23.44 ? 121 PHE E N 1 ATOM 7382 C CA . PHE E 1 140 ? -18.923 24.057 -17.410 1.00 26.06 ? 121 PHE E CA 1 ATOM 7383 C C . PHE E 1 140 ? -18.757 22.752 -16.662 1.00 29.31 ? 121 PHE E C 1 ATOM 7384 O O . PHE E 1 140 ? -18.817 21.665 -17.236 1.00 34.15 ? 121 PHE E O 1 ATOM 7385 C CB . PHE E 1 140 ? -20.309 24.597 -17.055 1.00 21.36 ? 121 PHE E CB 1 ATOM 7386 C CG . PHE E 1 140 ? -20.575 25.958 -17.590 1.00 26.36 ? 121 PHE E CG 1 ATOM 7387 C CD1 . PHE E 1 140 ? -21.108 26.117 -18.867 1.00 22.02 ? 121 PHE E CD1 1 ATOM 7388 C CD2 . PHE E 1 140 ? -20.280 27.089 -16.826 1.00 21.80 ? 121 PHE E CD2 1 ATOM 7389 C CE1 . PHE E 1 140 ? -21.352 27.382 -19.374 1.00 24.12 ? 121 PHE E CE1 1 ATOM 7390 C CE2 . PHE E 1 140 ? -20.519 28.356 -17.323 1.00 18.43 ? 121 PHE E CE2 1 ATOM 7391 C CZ . PHE E 1 140 ? -21.055 28.510 -18.601 1.00 19.70 ? 121 PHE E CZ 1 ATOM 7392 N N . SER E 1 141 ? -18.583 22.875 -15.356 1.00 30.21 ? 122 SER E N 1 ATOM 7393 C CA . SER E 1 141 ? -18.489 21.724 -14.472 1.00 26.55 ? 122 SER E CA 1 ATOM 7394 C C . SER E 1 141 ? -19.728 21.769 -13.581 1.00 30.05 ? 122 SER E C 1 ATOM 7395 O O . SER E 1 141 ? -19.923 22.718 -12.814 1.00 31.93 ? 122 SER E O 1 ATOM 7396 C CB . SER E 1 141 ? -17.204 21.802 -13.643 1.00 19.85 ? 122 SER E CB 1 ATOM 7397 O OG . SER E 1 141 ? -17.355 21.129 -12.410 1.00 27.38 ? 122 SER E OG 1 ATOM 7398 N N . CYS E 1 142 ? -20.579 20.757 -13.704 1.00 29.20 ? 123 CYS E N 1 ATOM 7399 C CA . CYS E 1 142 ? -21.826 20.717 -12.945 1.00 33.74 ? 123 CYS E CA 1 ATOM 7400 C C . CYS E 1 142 ? -22.399 19.300 -12.849 1.00 37.56 ? 123 CYS E C 1 ATOM 7401 O O . CYS E 1 142 ? -21.827 18.344 -13.393 1.00 30.37 ? 123 CYS E O 1 ATOM 7402 C CB . CYS E 1 142 ? -22.851 21.681 -13.557 1.00 36.10 ? 123 CYS E CB 1 ATOM 7403 S SG . CYS E 1 142 ? -23.120 21.431 -15.321 1.00 53.90 ? 123 CYS E SG 1 ATOM 7404 N N . ASP E 1 143 ? -23.533 19.176 -12.156 1.00 42.61 ? 124 ASP E N 1 ATOM 7405 C CA . ASP E 1 143 ? -24.170 17.876 -11.932 1.00 34.92 ? 124 ASP E CA 1 ATOM 7406 C C . ASP E 1 143 ? -24.938 17.423 -13.166 1.00 31.70 ? 124 ASP E C 1 ATOM 7407 O O . ASP E 1 143 ? -25.913 18.058 -13.570 1.00 34.08 ? 124 ASP E O 1 ATOM 7408 C CB . ASP E 1 143 ? -25.106 17.937 -10.723 1.00 33.69 ? 124 ASP E CB 1 ATOM 7409 C CG . ASP E 1 143 ? -25.455 16.566 -10.187 1.00 37.70 ? 124 ASP E CG 1 ATOM 7410 O OD1 . ASP E 1 143 ? -24.872 15.564 -10.665 1.00 44.86 ? 124 ASP E OD1 1 ATOM 7411 O OD2 . ASP E 1 143 ? -26.302 16.496 -9.273 1.00 38.83 ? 124 ASP E OD2 1 ATOM 7412 N N . VAL E 1 144 ? -24.488 16.319 -13.751 1.00 27.37 ? 125 VAL E N 1 ATOM 7413 C CA . VAL E 1 144 ? -25.013 15.825 -15.019 1.00 29.86 ? 125 VAL E CA 1 ATOM 7414 C C . VAL E 1 144 ? -25.820 14.519 -14.827 1.00 37.72 ? 125 VAL E C 1 ATOM 7415 O O . VAL E 1 144 ? -26.521 14.047 -15.733 1.00 32.09 ? 125 VAL E O 1 ATOM 7416 C CB . VAL E 1 144 ? -23.847 15.596 -16.005 1.00 27.97 ? 125 VAL E CB 1 ATOM 7417 C CG1 . VAL E 1 144 ? -24.343 15.112 -17.349 1.00 27.52 ? 125 VAL E CG1 1 ATOM 7418 C CG2 . VAL E 1 144 ? -23.041 16.863 -16.162 1.00 33.18 ? 125 VAL E CG2 1 ATOM 7419 N N . SER E 1 145 ? -25.716 13.943 -13.632 1.00 39.03 ? 126 SER E N 1 ATOM 7420 C CA . SER E 1 145 ? -26.389 12.687 -13.316 1.00 34.26 ? 126 SER E CA 1 ATOM 7421 C C . SER E 1 145 ? -27.894 12.759 -13.595 1.00 34.90 ? 126 SER E C 1 ATOM 7422 O O . SER E 1 145 ? -28.576 13.731 -13.229 1.00 32.93 ? 126 SER E O 1 ATOM 7423 C CB . SER E 1 145 ? -26.147 12.315 -11.853 1.00 32.52 ? 126 SER E CB 1 ATOM 7424 O OG . SER E 1 145 ? -26.644 13.332 -10.993 1.00 32.56 ? 126 SER E OG 1 ATOM 7425 N N . GLY E 1 146 ? -28.403 11.729 -14.263 1.00 38.81 ? 127 GLY E N 1 ATOM 7426 C CA . GLY E 1 146 ? -29.821 11.630 -14.547 1.00 37.24 ? 127 GLY E CA 1 ATOM 7427 C C . GLY E 1 146 ? -30.183 12.289 -15.857 1.00 38.04 ? 127 GLY E C 1 ATOM 7428 O O . GLY E 1 146 ? -31.351 12.564 -16.117 1.00 37.13 ? 127 GLY E O 1 ATOM 7429 N N . VAL E 1 147 ? -29.180 12.540 -16.691 1.00 36.36 ? 128 VAL E N 1 ATOM 7430 C CA . VAL E 1 147 ? -29.425 13.230 -17.949 1.00 38.93 ? 128 VAL E CA 1 ATOM 7431 C C . VAL E 1 147 ? -30.227 12.325 -18.886 1.00 38.52 ? 128 VAL E C 1 ATOM 7432 O O . VAL E 1 147 ? -30.984 12.798 -19.735 1.00 41.88 ? 128 VAL E O 1 ATOM 7433 C CB . VAL E 1 147 ? -28.096 13.716 -18.606 1.00 39.84 ? 128 VAL E CB 1 ATOM 7434 C CG1 . VAL E 1 147 ? -27.153 12.546 -18.852 1.00 29.67 ? 128 VAL E CG1 1 ATOM 7435 C CG2 . VAL E 1 147 ? -28.359 14.525 -19.896 1.00 30.86 ? 128 VAL E CG2 1 ATOM 7436 N N . ASP E 1 148 ? -30.075 11.018 -18.706 1.00 48.69 ? 129 ASP E N 1 ATOM 7437 C CA . ASP E 1 148 ? -30.770 10.043 -19.549 1.00 47.44 ? 129 ASP E CA 1 ATOM 7438 C C . ASP E 1 148 ? -32.014 9.451 -18.856 1.00 38.54 ? 129 ASP E C 1 ATOM 7439 O O . ASP E 1 148 ? -32.343 8.288 -19.024 1.00 37.51 ? 129 ASP E O 1 ATOM 7440 C CB . ASP E 1 148 ? -29.793 8.948 -19.980 1.00 48.20 ? 129 ASP E CB 1 ATOM 7441 C CG . ASP E 1 148 ? -30.054 8.456 -21.399 1.00 65.13 ? 129 ASP E CG 1 ATOM 7442 O OD1 . ASP E 1 148 ? -31.242 8.245 -21.755 1.00 53.27 ? 129 ASP E OD1 1 ATOM 7443 O OD2 . ASP E 1 148 ? -29.070 8.284 -22.159 1.00 78.11 ? 129 ASP E OD2 1 ATOM 7444 N N . THR E 1 149 ? -32.704 10.299 -18.102 1.00 37.15 ? 130 THR E N 1 ATOM 7445 C CA . THR E 1 149 ? -33.789 9.923 -17.204 1.00 35.49 ? 130 THR E CA 1 ATOM 7446 C C . THR E 1 149 ? -34.975 10.830 -17.502 1.00 45.92 ? 130 THR E C 1 ATOM 7447 O O . THR E 1 149 ? -34.806 11.911 -18.065 1.00 43.57 ? 130 THR E O 1 ATOM 7448 C CB . THR E 1 149 ? -33.332 10.104 -15.733 1.00 43.54 ? 130 THR E CB 1 ATOM 7449 O OG1 . THR E 1 149 ? -32.362 9.094 -15.415 1.00 59.25 ? 130 THR E OG1 1 ATOM 7450 C CG2 . THR E 1 149 ? -34.491 10.031 -14.728 1.00 42.59 ? 130 THR E CG2 1 ATOM 7451 N N . GLU E 1 150 ? -36.180 10.399 -17.154 1.00 53.73 ? 131 GLU E N 1 ATOM 7452 C CA . GLU E 1 150 ? -37.360 11.204 -17.435 1.00 55.60 ? 131 GLU E CA 1 ATOM 7453 C C . GLU E 1 150 ? -37.390 12.532 -16.647 1.00 52.21 ? 131 GLU E C 1 ATOM 7454 O O . GLU E 1 150 ? -37.986 13.517 -17.096 1.00 44.21 ? 131 GLU E O 1 ATOM 7455 C CB . GLU E 1 150 ? -38.616 10.382 -17.174 1.00 60.33 ? 131 GLU E CB 1 ATOM 7456 C CG . GLU E 1 150 ? -39.876 10.946 -17.793 1.00 61.84 ? 131 GLU E CG 1 ATOM 7457 C CD . GLU E 1 150 ? -41.129 10.401 -17.124 1.00 87.21 ? 131 GLU E CD 1 ATOM 7458 O OE1 . GLU E 1 150 ? -41.122 10.234 -15.878 1.00 88.29 ? 131 GLU E OE1 1 ATOM 7459 O OE2 . GLU E 1 150 ? -42.117 10.135 -17.846 1.00 88.07 ? 131 GLU E OE2 1 ATOM 7460 N N . SER E 1 151 ? -36.738 12.561 -15.484 1.00 47.90 ? 132 SER E N 1 ATOM 7461 C CA . SER E 1 151 ? -36.716 13.768 -14.642 1.00 39.70 ? 132 SER E CA 1 ATOM 7462 C C . SER E 1 151 ? -35.541 14.722 -14.934 1.00 41.00 ? 132 SER E C 1 ATOM 7463 O O . SER E 1 151 ? -35.547 15.888 -14.505 1.00 35.10 ? 132 SER E O 1 ATOM 7464 C CB . SER E 1 151 ? -36.745 13.384 -13.160 1.00 43.94 ? 132 SER E CB 1 ATOM 7465 O OG . SER E 1 151 ? -35.773 12.387 -12.888 1.00 65.81 ? 132 SER E OG 1 ATOM 7466 N N . GLY E 1 152 ? -34.538 14.222 -15.656 1.00 44.20 ? 133 GLY E N 1 ATOM 7467 C CA . GLY E 1 152 ? -33.456 15.051 -16.177 1.00 36.30 ? 133 GLY E CA 1 ATOM 7468 C C . GLY E 1 152 ? -32.350 15.378 -15.181 1.00 41.34 ? 133 GLY E C 1 ATOM 7469 O O . GLY E 1 152 ? -32.450 15.060 -13.988 1.00 40.54 ? 133 GLY E O 1 ATOM 7470 N N . ALA E 1 153 ? -31.286 16.010 -15.679 1.00 38.58 ? 134 ALA E N 1 ATOM 7471 C CA . ALA E 1 153 ? -30.228 16.548 -14.821 1.00 34.46 ? 134 ALA E CA 1 ATOM 7472 C C . ALA E 1 153 ? -30.500 18.021 -14.514 1.00 32.42 ? 134 ALA E C 1 ATOM 7473 O O . ALA E 1 153 ? -31.148 18.717 -15.296 1.00 34.19 ? 134 ALA E O 1 ATOM 7474 C CB . ALA E 1 153 ? -28.877 16.394 -15.491 1.00 36.07 ? 134 ALA E CB 1 ATOM 7475 N N . THR E 1 154 ? -30.011 18.498 -13.372 1.00 38.57 ? 135 THR E N 1 ATOM 7476 C CA . THR E 1 154 ? -30.068 19.929 -13.080 1.00 37.42 ? 135 THR E CA 1 ATOM 7477 C C . THR E 1 154 ? -28.676 20.518 -12.886 1.00 39.70 ? 135 THR E C 1 ATOM 7478 O O . THR E 1 154 ? -28.016 20.276 -11.869 1.00 37.59 ? 135 THR E O 1 ATOM 7479 C CB . THR E 1 154 ? -30.944 20.249 -11.864 1.00 45.63 ? 135 THR E CB 1 ATOM 7480 O OG1 . THR E 1 154 ? -32.201 19.564 -11.981 1.00 44.35 ? 135 THR E OG1 1 ATOM 7481 C CG2 . THR E 1 154 ? -31.190 21.762 -11.778 1.00 42.11 ? 135 THR E CG2 1 ATOM 7482 N N . CYS E 1 155 ? -28.245 21.281 -13.890 1.00 39.91 ? 136 CYS E N 1 ATOM 7483 C CA . CYS E 1 155 ? -26.950 21.946 -13.892 1.00 38.36 ? 136 CYS E CA 1 ATOM 7484 C C . CYS E 1 155 ? -27.093 23.416 -13.438 1.00 33.22 ? 136 CYS E C 1 ATOM 7485 O O . CYS E 1 155 ? -27.938 24.137 -13.962 1.00 33.71 ? 136 CYS E O 1 ATOM 7486 C CB . CYS E 1 155 ? -26.363 21.864 -15.299 1.00 28.52 ? 136 CYS E CB 1 ATOM 7487 S SG . CYS E 1 155 ? -24.746 22.663 -15.455 1.00 67.01 ? 136 CYS E SG 1 ATOM 7488 N N . ARG E 1 156 ? -26.291 23.852 -12.460 1.00 32.43 ? 137 ARG E N 1 ATOM 7489 C CA . ARG E 1 156 ? -26.323 25.255 -12.004 1.00 30.45 ? 137 ARG E CA 1 ATOM 7490 C C . ARG E 1 156 ? -25.114 26.064 -12.504 1.00 27.48 ? 137 ARG E C 1 ATOM 7491 O O . ARG E 1 156 ? -23.977 25.597 -12.475 1.00 30.13 ? 137 ARG E O 1 ATOM 7492 C CB . ARG E 1 156 ? -26.405 25.368 -10.473 1.00 31.09 ? 137 ARG E CB 1 ATOM 7493 C CG . ARG E 1 156 ? -27.340 24.392 -9.772 1.00 31.33 ? 137 ARG E CG 1 ATOM 7494 C CD . ARG E 1 156 ? -27.338 24.584 -8.234 1.00 46.46 ? 137 ARG E CD 1 ATOM 7495 N NE . ARG E 1 156 ? -26.046 25.011 -7.661 1.00 50.14 ? 137 ARG E NE 1 ATOM 7496 C CZ . ARG E 1 156 ? -25.109 24.193 -7.178 1.00 55.67 ? 137 ARG E CZ 1 ATOM 7497 N NH1 . ARG E 1 156 ? -25.292 22.877 -7.196 1.00 55.88 ? 137 ARG E NH1 1 ATOM 7498 N NH2 . ARG E 1 156 ? -23.981 24.691 -6.677 1.00 57.28 ? 137 ARG E NH2 1 ATOM 7499 N N . ILE E 1 157 ? -25.367 27.285 -12.953 1.00 28.66 ? 138 ILE E N 1 ATOM 7500 C CA . ILE E 1 157 ? -24.298 28.154 -13.414 1.00 25.20 ? 138 ILE E CA 1 ATOM 7501 C C . ILE E 1 157 ? -24.298 29.402 -12.556 1.00 23.24 ? 138 ILE E C 1 ATOM 7502 O O . ILE E 1 157 ? -25.319 30.073 -12.418 1.00 22.44 ? 138 ILE E O 1 ATOM 7503 C CB . ILE E 1 157 ? -24.484 28.549 -14.884 1.00 24.31 ? 138 ILE E CB 1 ATOM 7504 C CG1 . ILE E 1 157 ? -24.423 27.309 -15.769 1.00 20.39 ? 138 ILE E CG1 1 ATOM 7505 C CG2 . ILE E 1 157 ? -23.440 29.585 -15.308 1.00 24.60 ? 138 ILE E CG2 1 ATOM 7506 C CD1 . ILE E 1 157 ? -24.356 27.633 -17.234 1.00 22.63 ? 138 ILE E CD1 1 ATOM 7507 N N . LYS E 1 158 ? -23.144 29.707 -11.977 1.00 27.89 ? 139 LYS E N 1 ATOM 7508 C CA . LYS E 1 158 ? -23.016 30.829 -11.056 1.00 25.38 ? 139 LYS E CA 1 ATOM 7509 C C . LYS E 1 158 ? -22.244 31.988 -11.725 1.00 26.98 ? 139 LYS E C 1 ATOM 7510 O O . LYS E 1 158 ? -21.076 31.856 -12.128 1.00 24.12 ? 139 LYS E O 1 ATOM 7511 C CB . LYS E 1 158 ? -22.340 30.348 -9.765 1.00 25.17 ? 139 LYS E CB 1 ATOM 7512 C CG . LYS E 1 158 ? -22.025 31.442 -8.764 1.00 31.77 ? 139 LYS E CG 1 ATOM 7513 C CD . LYS E 1 158 ? -21.034 30.929 -7.703 1.00 38.44 ? 139 LYS E CD 1 ATOM 7514 C CE . LYS E 1 158 ? -20.328 32.062 -6.956 1.00 37.62 ? 139 LYS E CE 1 ATOM 7515 N NZ . LYS E 1 158 ? -19.466 31.544 -5.841 1.00 33.04 ? 139 LYS E NZ 1 ATOM 7516 N N . ILE E 1 159 ? -22.908 33.126 -11.857 1.00 21.61 ? 140 ILE E N 1 ATOM 7517 C CA . ILE E 1 159 ? -22.317 34.268 -12.536 1.00 18.46 ? 140 ILE E CA 1 ATOM 7518 C C . ILE E 1 159 ? -22.339 35.506 -11.642 1.00 22.32 ? 140 ILE E C 1 ATOM 7519 O O . ILE E 1 159 ? -23.381 35.867 -11.104 1.00 25.18 ? 140 ILE E O 1 ATOM 7520 C CB . ILE E 1 159 ? -23.088 34.573 -13.822 1.00 21.49 ? 140 ILE E CB 1 ATOM 7521 C CG1 . ILE E 1 159 ? -22.959 33.406 -14.793 1.00 22.20 ? 140 ILE E CG1 1 ATOM 7522 C CG2 . ILE E 1 159 ? -22.594 35.842 -14.475 1.00 18.66 ? 140 ILE E CG2 1 ATOM 7523 C CD1 . ILE E 1 159 ? -23.623 33.675 -16.114 1.00 19.48 ? 140 ILE E CD1 1 ATOM 7524 N N . GLY E 1 160 ? -21.191 36.165 -11.494 1.00 23.49 ? 141 GLY E N 1 ATOM 7525 C CA . GLY E 1 160 ? -21.118 37.382 -10.711 1.00 20.99 ? 141 GLY E CA 1 ATOM 7526 C C . GLY E 1 160 ? -19.941 38.270 -11.065 1.00 20.18 ? 141 GLY E C 1 ATOM 7527 O O . GLY E 1 160 ? -19.121 37.912 -11.913 1.00 19.27 ? 141 GLY E O 1 ATOM 7528 N N . SER E 1 161 ? -19.860 39.435 -10.418 1.00 24.03 ? 142 SER E N 1 ATOM 7529 C CA . SER E 1 161 ? -18.700 40.321 -10.555 1.00 19.72 ? 142 SER E CA 1 ATOM 7530 C C . SER E 1 161 ? -17.455 39.706 -9.941 1.00 21.61 ? 142 SER E C 1 ATOM 7531 O O . SER E 1 161 ? -17.500 39.186 -8.822 1.00 24.72 ? 142 SER E O 1 ATOM 7532 C CB . SER E 1 161 ? -18.954 41.654 -9.860 1.00 20.92 ? 142 SER E CB 1 ATOM 7533 O OG . SER E 1 161 ? -17.780 42.457 -9.918 1.00 27.00 ? 142 SER E OG 1 ATOM 7534 N N . TRP E 1 162 ? -16.336 39.798 -10.654 1.00 20.38 ? 143 TRP E N 1 ATOM 7535 C CA . TRP E 1 162 ? -15.086 39.176 -10.198 1.00 20.80 ? 143 TRP E CA 1 ATOM 7536 C C . TRP E 1 162 ? -14.304 39.992 -9.176 1.00 23.03 ? 143 TRP E C 1 ATOM 7537 O O . TRP E 1 162 ? -13.644 39.416 -8.293 1.00 21.32 ? 143 TRP E O 1 ATOM 7538 C CB . TRP E 1 162 ? -14.174 38.841 -11.379 1.00 17.38 ? 143 TRP E CB 1 ATOM 7539 C CG . TRP E 1 162 ? -13.086 37.850 -11.008 1.00 20.96 ? 143 TRP E CG 1 ATOM 7540 C CD1 . TRP E 1 162 ? -11.749 38.107 -10.856 1.00 16.67 ? 143 TRP E CD1 1 ATOM 7541 C CD2 . TRP E 1 162 ? -13.259 36.448 -10.743 1.00 19.40 ? 143 TRP E CD2 1 ATOM 7542 N NE1 . TRP E 1 162 ? -11.086 36.956 -10.527 1.00 17.38 ? 143 TRP E NE1 1 ATOM 7543 C CE2 . TRP E 1 162 ? -11.985 35.926 -10.437 1.00 21.32 ? 143 TRP E CE2 1 ATOM 7544 C CE3 . TRP E 1 162 ? -14.370 35.595 -10.717 1.00 18.47 ? 143 TRP E CE3 1 ATOM 7545 C CZ2 . TRP E 1 162 ? -11.791 34.579 -10.108 1.00 21.64 ? 143 TRP E CZ2 1 ATOM 7546 C CZ3 . TRP E 1 162 ? -14.181 34.263 -10.399 1.00 21.58 ? 143 TRP E CZ3 1 ATOM 7547 C CH2 . TRP E 1 162 ? -12.894 33.765 -10.101 1.00 24.79 ? 143 TRP E CH2 1 ATOM 7548 N N . THR E 1 163 ? -14.370 41.324 -9.311 1.00 21.64 ? 144 THR E N 1 ATOM 7549 C CA . THR E 1 163 ? -13.595 42.231 -8.458 1.00 18.67 ? 144 THR E CA 1 ATOM 7550 C C . THR E 1 163 ? -14.410 43.278 -7.707 1.00 16.69 ? 144 THR E C 1 ATOM 7551 O O . THR E 1 163 ? -13.870 43.984 -6.863 1.00 27.45 ? 144 THR E O 1 ATOM 7552 C CB . THR E 1 163 ? -12.461 42.962 -9.227 1.00 13.07 ? 144 THR E CB 1 ATOM 7553 O OG1 . THR E 1 163 ? -13.033 43.878 -10.159 1.00 20.80 ? 144 THR E OG1 1 ATOM 7554 C CG2 . THR E 1 163 ? -11.588 41.993 -9.966 1.00 14.64 ? 144 THR E CG2 1 ATOM 7555 N N . HIS E 1 164 ? -15.687 43.414 -8.009 1.00 14.84 ? 145 HIS E N 1 ATOM 7556 C CA . HIS E 1 164 ? -16.477 44.445 -7.336 1.00 20.17 ? 145 HIS E CA 1 ATOM 7557 C C . HIS E 1 164 ? -17.467 43.868 -6.308 1.00 26.67 ? 145 HIS E C 1 ATOM 7558 O O . HIS E 1 164 ? -18.277 43.000 -6.639 1.00 25.93 ? 145 HIS E O 1 ATOM 7559 C CB . HIS E 1 164 ? -17.227 45.309 -8.356 1.00 19.86 ? 145 HIS E CB 1 ATOM 7560 C CG . HIS E 1 164 ? -16.334 46.148 -9.208 1.00 22.29 ? 145 HIS E CG 1 ATOM 7561 N ND1 . HIS E 1 164 ? -15.665 47.245 -8.746 1.00 22.16 ? 145 HIS E ND1 1 ATOM 7562 C CD2 . HIS E 1 164 ? -15.999 46.042 -10.538 1.00 22.80 ? 145 HIS E CD2 1 ATOM 7563 C CE1 . HIS E 1 164 ? -14.952 47.799 -9.724 1.00 20.87 ? 145 HIS E CE1 1 ATOM 7564 N NE2 . HIS E 1 164 ? -15.156 47.072 -10.815 1.00 21.60 ? 145 HIS E NE2 1 ATOM 7565 N N . HIS E 1 165 ? -17.417 44.357 -5.069 1.00 25.06 ? 146 HIS E N 1 ATOM 7566 C CA . HIS E 1 165 ? -18.322 43.861 -4.037 1.00 26.38 ? 146 HIS E CA 1 ATOM 7567 C C . HIS E 1 165 ? -19.736 44.465 -4.126 1.00 28.13 ? 146 HIS E C 1 ATOM 7568 O O . HIS E 1 165 ? -20.036 45.230 -5.037 1.00 27.04 ? 146 HIS E O 1 ATOM 7569 C CB . HIS E 1 165 ? -17.718 44.024 -2.644 1.00 28.50 ? 146 HIS E CB 1 ATOM 7570 C CG . HIS E 1 165 ? -17.429 45.445 -2.274 1.00 37.18 ? 146 HIS E CG 1 ATOM 7571 N ND1 . HIS E 1 165 ? -18.411 46.392 -2.138 1.00 34.62 ? 146 HIS E ND1 1 ATOM 7572 C CD2 . HIS E 1 165 ? -16.250 46.066 -2.002 1.00 41.24 ? 146 HIS E CD2 1 ATOM 7573 C CE1 . HIS E 1 165 ? -17.856 47.551 -1.799 1.00 39.95 ? 146 HIS E CE1 1 ATOM 7574 N NE2 . HIS E 1 165 ? -16.553 47.372 -1.706 1.00 39.30 ? 146 HIS E NE2 1 ATOM 7575 N N . SER E 1 166 ? -20.600 44.107 -3.178 1.00 29.97 ? 147 SER E N 1 ATOM 7576 C CA . SER E 1 166 ? -22.042 44.371 -3.274 1.00 30.77 ? 147 SER E CA 1 ATOM 7577 C C . SER E 1 166 ? -22.449 45.843 -3.222 1.00 33.93 ? 147 SER E C 1 ATOM 7578 O O . SER E 1 166 ? -23.582 46.182 -3.579 1.00 32.78 ? 147 SER E O 1 ATOM 7579 C CB . SER E 1 166 ? -22.786 43.632 -2.165 1.00 32.15 ? 147 SER E CB 1 ATOM 7580 O OG . SER E 1 166 ? -22.396 44.152 -0.904 1.00 34.65 ? 147 SER E OG 1 ATOM 7581 N N . ARG E 1 167 ? -21.554 46.708 -2.746 1.00 38.47 ? 148 ARG E N 1 ATOM 7582 C CA . ARG E 1 167 ? -21.844 48.147 -2.688 1.00 40.09 ? 148 ARG E CA 1 ATOM 7583 C C . ARG E 1 167 ? -21.381 48.871 -3.951 1.00 34.02 ? 148 ARG E C 1 ATOM 7584 O O . ARG E 1 167 ? -21.656 50.057 -4.135 1.00 35.89 ? 148 ARG E O 1 ATOM 7585 C CB . ARG E 1 167 ? -21.214 48.810 -1.458 1.00 40.67 ? 148 ARG E CB 1 ATOM 7586 C CG . ARG E 1 167 ? -21.769 48.340 -0.115 1.00 52.29 ? 148 ARG E CG 1 ATOM 7587 C CD . ARG E 1 167 ? -21.108 49.096 1.050 1.00 69.69 ? 148 ARG E CD 1 ATOM 7588 N NE . ARG E 1 167 ? -19.880 49.798 0.651 1.00 73.87 ? 148 ARG E NE 1 ATOM 7589 C CZ . ARG E 1 167 ? -18.750 49.818 1.358 1.00 81.58 ? 148 ARG E CZ 1 ATOM 7590 N NH1 . ARG E 1 167 ? -18.679 49.163 2.516 1.00 85.39 ? 148 ARG E NH1 1 ATOM 7591 N NH2 . ARG E 1 167 ? -17.689 50.489 0.902 1.00 70.29 ? 148 ARG E NH2 1 ATOM 7592 N N . GLU E 1 168 ? -20.676 48.146 -4.812 1.00 29.43 ? 149 GLU E N 1 ATOM 7593 C CA . GLU E 1 168 ? -20.219 48.686 -6.084 1.00 28.72 ? 149 GLU E CA 1 ATOM 7594 C C . GLU E 1 168 ? -21.015 48.127 -7.278 1.00 25.14 ? 149 GLU E C 1 ATOM 7595 O O . GLU E 1 168 ? -21.447 48.872 -8.150 1.00 28.43 ? 149 GLU E O 1 ATOM 7596 C CB . GLU E 1 168 ? -18.708 48.445 -6.253 1.00 31.00 ? 149 GLU E CB 1 ATOM 7597 C CG . GLU E 1 168 ? -17.839 49.188 -5.239 1.00 38.60 ? 149 GLU E CG 1 ATOM 7598 C CD . GLU E 1 168 ? -16.354 48.830 -5.324 1.00 45.05 ? 149 GLU E CD 1 ATOM 7599 O OE1 . GLU E 1 168 ? -16.050 47.647 -5.621 1.00 41.58 ? 149 GLU E OE1 1 ATOM 7600 O OE2 . GLU E 1 168 ? -15.497 49.730 -5.088 1.00 51.81 ? 149 GLU E OE2 1 ATOM 7601 N N . ILE E 1 169 ? -21.198 46.813 -7.319 1.00 25.66 ? 150 ILE E N 1 ATOM 7602 C CA . ILE E 1 169 ? -22.054 46.190 -8.328 1.00 21.50 ? 150 ILE E CA 1 ATOM 7603 C C . ILE E 1 169 ? -23.018 45.252 -7.637 1.00 25.02 ? 150 ILE E C 1 ATOM 7604 O O . ILE E 1 169 ? -22.599 44.416 -6.818 1.00 26.39 ? 150 ILE E O 1 ATOM 7605 C CB . ILE E 1 169 ? -21.235 45.385 -9.357 1.00 18.29 ? 150 ILE E CB 1 ATOM 7606 C CG1 . ILE E 1 169 ? -20.471 46.331 -10.287 1.00 18.47 ? 150 ILE E CG1 1 ATOM 7607 C CG2 . ILE E 1 169 ? -22.129 44.478 -10.162 1.00 14.35 ? 150 ILE E CG2 1 ATOM 7608 C CD1 . ILE E 1 169 ? -19.711 45.649 -11.427 1.00 10.41 ? 150 ILE E CD1 1 ATOM 7609 N N . SER E 1 170 ? -24.306 45.407 -7.936 1.00 21.45 ? 151 SER E N 1 ATOM 7610 C CA . SER E 1 170 ? -25.300 44.389 -7.576 1.00 29.25 ? 151 SER E CA 1 ATOM 7611 C C . SER E 1 170 ? -25.845 43.668 -8.832 1.00 33.39 ? 151 SER E C 1 ATOM 7612 O O . SER E 1 170 ? -26.228 44.313 -9.827 1.00 32.44 ? 151 SER E O 1 ATOM 7613 C CB . SER E 1 170 ? -26.437 45.009 -6.757 1.00 27.41 ? 151 SER E CB 1 ATOM 7614 O OG . SER E 1 170 ? -27.257 45.823 -7.567 1.00 30.82 ? 151 SER E OG 1 ATOM 7615 N N . VAL E 1 171 ? -25.876 42.337 -8.798 1.00 30.77 ? 152 VAL E N 1 ATOM 7616 C CA . VAL E 1 171 ? -26.465 41.575 -9.904 1.00 30.94 ? 152 VAL E CA 1 ATOM 7617 C C . VAL E 1 171 ? -27.808 41.038 -9.494 1.00 27.07 ? 152 VAL E C 1 ATOM 7618 O O . VAL E 1 171 ? -27.972 40.584 -8.378 1.00 32.50 ? 152 VAL E O 1 ATOM 7619 C CB . VAL E 1 171 ? -25.596 40.391 -10.346 1.00 27.40 ? 152 VAL E CB 1 ATOM 7620 C CG1 . VAL E 1 171 ? -24.482 40.866 -11.242 1.00 22.86 ? 152 VAL E CG1 1 ATOM 7621 C CG2 . VAL E 1 171 ? -25.037 39.676 -9.138 1.00 29.17 ? 152 VAL E CG2 1 ATOM 7622 N N . ASP E 1 172 ? -28.761 41.084 -10.415 1.00 37.42 ? 153 ASP E N 1 ATOM 7623 C CA . ASP E 1 172 ? -30.134 40.658 -10.159 1.00 38.14 ? 153 ASP E CA 1 ATOM 7624 C C . ASP E 1 172 ? -30.673 39.937 -11.386 1.00 38.24 ? 153 ASP E C 1 ATOM 7625 O O . ASP E 1 172 ? -30.320 40.292 -12.505 1.00 37.05 ? 153 ASP E O 1 ATOM 7626 C CB . ASP E 1 172 ? -31.013 41.872 -9.863 1.00 39.30 ? 153 ASP E CB 1 ATOM 7627 C CG . ASP E 1 172 ? -30.306 42.909 -8.989 1.00 52.80 ? 153 ASP E CG 1 ATOM 7628 O OD1 . ASP E 1 172 ? -30.242 42.703 -7.748 1.00 58.71 ? 153 ASP E OD1 1 ATOM 7629 O OD2 . ASP E 1 172 ? -29.811 43.923 -9.547 1.00 49.29 ? 153 ASP E OD2 1 ATOM 7630 N N . PRO E 1 173 ? -31.509 38.903 -11.177 1.00 40.38 ? 154 PRO E N 1 ATOM 7631 C CA . PRO E 1 173 ? -32.187 38.210 -12.279 1.00 34.61 ? 154 PRO E CA 1 ATOM 7632 C C . PRO E 1 173 ? -33.271 39.097 -12.874 1.00 47.83 ? 154 PRO E C 1 ATOM 7633 O O . PRO E 1 173 ? -33.770 39.988 -12.182 1.00 46.47 ? 154 PRO E O 1 ATOM 7634 C CB . PRO E 1 173 ? -32.843 37.031 -11.588 1.00 33.32 ? 154 PRO E CB 1 ATOM 7635 C CG . PRO E 1 173 ? -32.123 36.897 -10.288 1.00 30.31 ? 154 PRO E CG 1 ATOM 7636 C CD . PRO E 1 173 ? -31.764 38.253 -9.881 1.00 30.96 ? 154 PRO E CD 1 ATOM 7637 N N . THR E 1 174 ? -33.639 38.848 -14.129 1.00 54.89 ? 155 THR E N 1 ATOM 7638 C CA . THR E 1 174 ? -34.594 39.703 -14.835 1.00 52.37 ? 155 THR E CA 1 ATOM 7639 C C . THR E 1 174 ? -36.042 39.373 -14.488 1.00 49.74 ? 155 THR E C 1 ATOM 7640 O O . THR E 1 174 ? -36.412 38.208 -14.377 1.00 53.83 ? 155 THR E O 1 ATOM 7641 C CB . THR E 1 174 ? -34.391 39.616 -16.360 1.00 64.53 ? 155 THR E CB 1 ATOM 7642 O OG1 . THR E 1 174 ? -33.139 40.232 -16.710 1.00 58.65 ? 155 THR E OG1 1 ATOM 7643 C CG2 . THR E 1 174 ? -35.532 40.313 -17.097 1.00 75.58 ? 155 THR E CG2 1 ATOM 7644 N N . SER E 1 178 ? -40.763 34.218 -18.463 1.00 71.66 ? 159 SER E N 1 ATOM 7645 C CA . SER E 1 178 ? -40.084 33.873 -19.713 1.00 74.06 ? 159 SER E CA 1 ATOM 7646 C C . SER E 1 178 ? -40.530 32.520 -20.275 1.00 75.74 ? 159 SER E C 1 ATOM 7647 O O . SER E 1 178 ? -41.459 31.894 -19.755 1.00 70.65 ? 159 SER E O 1 ATOM 7648 C CB . SER E 1 178 ? -38.563 33.867 -19.518 1.00 70.05 ? 159 SER E CB 1 ATOM 7649 O OG . SER E 1 178 ? -38.070 35.153 -19.185 1.00 66.70 ? 159 SER E OG 1 ATOM 7650 N N . ASP E 1 179 ? -39.873 32.092 -21.353 1.00 78.45 ? 160 ASP E N 1 ATOM 7651 C CA . ASP E 1 179 ? -39.988 30.714 -21.853 1.00 72.55 ? 160 ASP E CA 1 ATOM 7652 C C . ASP E 1 179 ? -38.596 30.145 -22.162 1.00 74.95 ? 160 ASP E C 1 ATOM 7653 O O . ASP E 1 179 ? -37.895 30.659 -23.044 1.00 76.67 ? 160 ASP E O 1 ATOM 7654 C CB . ASP E 1 179 ? -40.885 30.630 -23.093 1.00 64.17 ? 160 ASP E CB 1 ATOM 7655 C CG . ASP E 1 179 ? -40.953 29.205 -23.683 1.00 81.47 ? 160 ASP E CG 1 ATOM 7656 O OD1 . ASP E 1 179 ? -40.833 28.210 -22.920 1.00 84.32 ? 160 ASP E OD1 1 ATOM 7657 O OD2 . ASP E 1 179 ? -41.129 29.077 -24.918 1.00 81.19 ? 160 ASP E OD2 1 ATOM 7658 N N . ASP E 1 180 ? -38.217 29.085 -21.434 1.00 65.91 ? 161 ASP E N 1 ATOM 7659 C CA . ASP E 1 180 ? -36.855 28.523 -21.454 1.00 57.85 ? 161 ASP E CA 1 ATOM 7660 C C . ASP E 1 180 ? -36.349 28.268 -22.861 1.00 57.63 ? 161 ASP E C 1 ATOM 7661 O O . ASP E 1 180 ? -35.258 28.708 -23.261 1.00 48.23 ? 161 ASP E O 1 ATOM 7662 C CB . ASP E 1 180 ? -36.799 27.179 -20.713 1.00 59.95 ? 161 ASP E CB 1 ATOM 7663 C CG . ASP E 1 180 ? -37.987 26.942 -19.770 1.00 70.88 ? 161 ASP E CG 1 ATOM 7664 O OD1 . ASP E 1 180 ? -38.148 27.731 -18.804 1.00 67.38 ? 161 ASP E OD1 1 ATOM 7665 O OD2 . ASP E 1 180 ? -38.717 25.925 -19.962 1.00 68.08 ? 161 ASP E OD2 1 ATOM 7666 N N . SER E 1 181 ? -37.196 27.546 -23.589 1.00 64.17 ? 162 SER E N 1 ATOM 7667 C CA . SER E 1 181 ? -36.912 26.964 -24.896 1.00 66.51 ? 162 SER E CA 1 ATOM 7668 C C . SER E 1 181 ? -37.200 27.932 -26.037 1.00 66.11 ? 162 SER E C 1 ATOM 7669 O O . SER E 1 181 ? -37.206 27.524 -27.209 1.00 66.94 ? 162 SER E O 1 ATOM 7670 C CB . SER E 1 181 ? -37.776 25.699 -25.098 1.00 62.23 ? 162 SER E CB 1 ATOM 7671 O OG . SER E 1 181 ? -37.305 24.583 -24.346 1.00 60.03 ? 162 SER E OG 1 ATOM 7672 N N . GLU E 1 182 ? -37.442 29.197 -25.702 1.00 55.07 ? 163 GLU E N 1 ATOM 7673 C CA . GLU E 1 182 ? -37.920 30.157 -26.686 1.00 51.46 ? 163 GLU E CA 1 ATOM 7674 C C . GLU E 1 182 ? -36.986 30.264 -27.889 1.00 52.60 ? 163 GLU E C 1 ATOM 7675 O O . GLU E 1 182 ? -37.445 30.361 -29.031 1.00 54.22 ? 163 GLU E O 1 ATOM 7676 C CB . GLU E 1 182 ? -38.130 31.526 -26.048 1.00 60.70 ? 163 GLU E CB 1 ATOM 7677 C CG . GLU E 1 182 ? -38.846 32.509 -26.957 1.00 63.64 ? 163 GLU E CG 1 ATOM 7678 C CD . GLU E 1 182 ? -38.954 33.908 -26.362 1.00 74.48 ? 163 GLU E CD 1 ATOM 7679 O OE1 . GLU E 1 182 ? -38.526 34.118 -25.198 1.00 71.07 ? 163 GLU E OE1 1 ATOM 7680 O OE2 . GLU E 1 182 ? -39.474 34.802 -27.072 1.00 89.65 ? 163 GLU E OE2 1 ATOM 7681 N N . TYR E 1 183 ? -35.679 30.234 -27.631 1.00 47.49 ? 164 TYR E N 1 ATOM 7682 C CA . TYR E 1 183 ? -34.692 30.260 -28.709 1.00 42.13 ? 164 TYR E CA 1 ATOM 7683 C C . TYR E 1 183 ? -33.866 28.983 -28.760 1.00 42.69 ? 164 TYR E C 1 ATOM 7684 O O . TYR E 1 183 ? -32.835 28.941 -29.435 1.00 34.22 ? 164 TYR E O 1 ATOM 7685 C CB . TYR E 1 183 ? -33.750 31.446 -28.557 1.00 37.02 ? 164 TYR E CB 1 ATOM 7686 C CG . TYR E 1 183 ? -34.451 32.761 -28.362 1.00 48.55 ? 164 TYR E CG 1 ATOM 7687 C CD1 . TYR E 1 183 ? -35.281 33.274 -29.351 1.00 54.20 ? 164 TYR E CD1 1 ATOM 7688 C CD2 . TYR E 1 183 ? -34.281 33.495 -27.189 1.00 42.05 ? 164 TYR E CD2 1 ATOM 7689 C CE1 . TYR E 1 183 ? -35.932 34.487 -29.186 1.00 60.24 ? 164 TYR E CE1 1 ATOM 7690 C CE2 . TYR E 1 183 ? -34.926 34.705 -27.004 1.00 43.08 ? 164 TYR E CE2 1 ATOM 7691 C CZ . TYR E 1 183 ? -35.753 35.203 -28.012 1.00 60.42 ? 164 TYR E CZ 1 ATOM 7692 O OH . TYR E 1 183 ? -36.411 36.415 -27.861 1.00 62.24 ? 164 TYR E OH 1 ATOM 7693 N N . PHE E 1 184 ? -34.312 27.952 -28.038 1.00 44.64 ? 165 PHE E N 1 ATOM 7694 C CA . PHE E 1 184 ? -33.560 26.706 -27.961 1.00 31.77 ? 165 PHE E CA 1 ATOM 7695 C C . PHE E 1 184 ? -33.690 25.928 -29.245 1.00 32.44 ? 165 PHE E C 1 ATOM 7696 O O . PHE E 1 184 ? -34.770 25.881 -29.834 1.00 40.01 ? 165 PHE E O 1 ATOM 7697 C CB . PHE E 1 184 ? -33.998 25.846 -26.784 1.00 30.15 ? 165 PHE E CB 1 ATOM 7698 C CG . PHE E 1 184 ? -33.029 24.747 -26.464 1.00 29.04 ? 165 PHE E CG 1 ATOM 7699 C CD1 . PHE E 1 184 ? -31.781 25.041 -25.948 1.00 23.99 ? 165 PHE E CD1 1 ATOM 7700 C CD2 . PHE E 1 184 ? -33.362 23.422 -26.680 1.00 32.33 ? 165 PHE E CD2 1 ATOM 7701 C CE1 . PHE E 1 184 ? -30.886 24.029 -25.658 1.00 28.17 ? 165 PHE E CE1 1 ATOM 7702 C CE2 . PHE E 1 184 ? -32.471 22.399 -26.389 1.00 26.72 ? 165 PHE E CE2 1 ATOM 7703 C CZ . PHE E 1 184 ? -31.238 22.697 -25.881 1.00 27.39 ? 165 PHE E CZ 1 ATOM 7704 N N . SER E 1 185 ? -32.584 25.326 -29.674 1.00 30.97 ? 166 SER E N 1 ATOM 7705 C CA . SER E 1 185 ? -32.522 24.626 -30.953 1.00 33.64 ? 166 SER E CA 1 ATOM 7706 C C . SER E 1 185 ? -33.348 23.349 -30.938 1.00 37.50 ? 166 SER E C 1 ATOM 7707 O O . SER E 1 185 ? -33.204 22.512 -30.040 1.00 42.08 ? 166 SER E O 1 ATOM 7708 C CB . SER E 1 185 ? -31.070 24.291 -31.305 1.00 31.87 ? 166 SER E CB 1 ATOM 7709 O OG . SER E 1 185 ? -31.001 23.695 -32.588 1.00 33.76 ? 166 SER E OG 1 ATOM 7710 N N . GLN E 1 186 ? -34.211 23.200 -31.937 1.00 38.72 ? 167 GLN E N 1 ATOM 7711 C CA . GLN E 1 186 ? -34.979 21.965 -32.103 1.00 41.98 ? 167 GLN E CA 1 ATOM 7712 C C . GLN E 1 186 ? -34.082 20.799 -32.519 1.00 40.82 ? 167 GLN E C 1 ATOM 7713 O O . GLN E 1 186 ? -34.468 19.645 -32.379 1.00 42.77 ? 167 GLN E O 1 ATOM 7714 C CB . GLN E 1 186 ? -36.083 22.157 -33.145 1.00 38.89 ? 167 GLN E CB 1 ATOM 7715 C CG . GLN E 1 186 ? -35.657 23.047 -34.303 1.00 44.95 ? 167 GLN E CG 1 ATOM 7716 C CD . GLN E 1 186 ? -36.670 23.115 -35.440 1.00 55.68 ? 167 GLN E CD 1 ATOM 7717 O OE1 . GLN E 1 186 ? -37.425 22.165 -35.695 1.00 60.91 ? 167 GLN E OE1 1 ATOM 7718 N NE2 . GLN E 1 186 ? -36.674 24.247 -36.144 1.00 61.74 ? 167 GLN E NE2 1 ATOM 7719 N N . TYR E 1 187 ? -32.885 21.098 -33.025 1.00 35.69 ? 168 TYR E N 1 ATOM 7720 C CA . TYR E 1 187 ? -32.004 20.047 -33.540 1.00 34.64 ? 168 TYR E CA 1 ATOM 7721 C C . TYR E 1 187 ? -31.014 19.495 -32.505 1.00 32.67 ? 168 TYR E C 1 ATOM 7722 O O . TYR E 1 187 ? -30.285 18.538 -32.774 1.00 31.69 ? 168 TYR E O 1 ATOM 7723 C CB . TYR E 1 187 ? -31.306 20.508 -34.837 1.00 33.90 ? 168 TYR E CB 1 ATOM 7724 C CG . TYR E 1 187 ? -32.300 20.957 -35.891 1.00 37.68 ? 168 TYR E CG 1 ATOM 7725 C CD1 . TYR E 1 187 ? -33.224 20.063 -36.419 1.00 45.52 ? 168 TYR E CD1 1 ATOM 7726 C CD2 . TYR E 1 187 ? -32.339 22.268 -36.335 1.00 38.01 ? 168 TYR E CD2 1 ATOM 7727 C CE1 . TYR E 1 187 ? -34.153 20.454 -37.365 1.00 41.15 ? 168 TYR E CE1 1 ATOM 7728 C CE2 . TYR E 1 187 ? -33.270 22.676 -37.290 1.00 44.84 ? 168 TYR E CE2 1 ATOM 7729 C CZ . TYR E 1 187 ? -34.172 21.754 -37.801 1.00 47.55 ? 168 TYR E CZ 1 ATOM 7730 O OH . TYR E 1 187 ? -35.109 22.120 -38.744 1.00 52.14 ? 168 TYR E OH 1 ATOM 7731 N N . SER E 1 188 ? -30.994 20.093 -31.318 1.00 32.54 ? 169 SER E N 1 ATOM 7732 C CA . SER E 1 188 ? -30.170 19.580 -30.222 1.00 33.16 ? 169 SER E CA 1 ATOM 7733 C C . SER E 1 188 ? -30.563 18.136 -29.885 1.00 30.90 ? 169 SER E C 1 ATOM 7734 O O . SER E 1 188 ? -31.703 17.729 -30.118 1.00 35.55 ? 169 SER E O 1 ATOM 7735 C CB . SER E 1 188 ? -30.318 20.477 -28.978 1.00 30.01 ? 169 SER E CB 1 ATOM 7736 O OG . SER E 1 188 ? -29.451 20.056 -27.938 1.00 31.30 ? 169 SER E OG 1 ATOM 7737 N N . ARG E 1 189 ? -29.626 17.359 -29.349 1.00 29.65 ? 170 ARG E N 1 ATOM 7738 C CA . ARG E 1 189 ? -29.958 16.023 -28.843 1.00 30.35 ? 170 ARG E CA 1 ATOM 7739 C C . ARG E 1 189 ? -30.667 16.100 -27.485 1.00 35.86 ? 170 ARG E C 1 ATOM 7740 O O . ARG E 1 189 ? -31.011 15.073 -26.895 1.00 32.31 ? 170 ARG E O 1 ATOM 7741 C CB . ARG E 1 189 ? -28.709 15.147 -28.689 1.00 27.84 ? 170 ARG E CB 1 ATOM 7742 C CG . ARG E 1 189 ? -27.964 14.875 -29.963 1.00 36.23 ? 170 ARG E CG 1 ATOM 7743 C CD . ARG E 1 189 ? -27.481 13.444 -29.996 1.00 49.29 ? 170 ARG E CD 1 ATOM 7744 N NE . ARG E 1 189 ? -26.515 13.123 -28.943 1.00 57.93 ? 170 ARG E NE 1 ATOM 7745 C CZ . ARG E 1 189 ? -26.270 11.884 -28.501 1.00 66.02 ? 170 ARG E CZ 1 ATOM 7746 N NH1 . ARG E 1 189 ? -26.931 10.839 -29.001 1.00 55.83 ? 170 ARG E NH1 1 ATOM 7747 N NH2 . ARG E 1 189 ? -25.369 11.685 -27.544 1.00 63.98 ? 170 ARG E NH2 1 ATOM 7748 N N . PHE E 1 190 ? -30.852 17.316 -26.974 1.00 31.64 ? 171 PHE E N 1 ATOM 7749 C CA . PHE E 1 190 ? -31.402 17.487 -25.635 1.00 29.32 ? 171 PHE E CA 1 ATOM 7750 C C . PHE E 1 190 ? -32.594 18.428 -25.645 1.00 27.79 ? 171 PHE E C 1 ATOM 7751 O O . PHE E 1 190 ? -32.830 19.143 -26.632 1.00 30.80 ? 171 PHE E O 1 ATOM 7752 C CB . PHE E 1 190 ? -30.331 18.013 -24.678 1.00 25.59 ? 171 PHE E CB 1 ATOM 7753 C CG . PHE E 1 190 ? -29.078 17.175 -24.640 1.00 22.89 ? 171 PHE E CG 1 ATOM 7754 C CD1 . PHE E 1 190 ? -28.076 17.360 -25.588 1.00 20.22 ? 171 PHE E CD1 1 ATOM 7755 C CD2 . PHE E 1 190 ? -28.889 16.221 -23.637 1.00 24.36 ? 171 PHE E CD2 1 ATOM 7756 C CE1 . PHE E 1 190 ? -26.908 16.597 -25.552 1.00 24.64 ? 171 PHE E CE1 1 ATOM 7757 C CE2 . PHE E 1 190 ? -27.722 15.447 -23.591 1.00 28.33 ? 171 PHE E CE2 1 ATOM 7758 C CZ . PHE E 1 190 ? -26.729 15.635 -24.556 1.00 24.53 ? 171 PHE E CZ 1 ATOM 7759 N N . GLU E 1 191 ? -33.346 18.422 -24.549 1.00 20.39 ? 172 GLU E N 1 ATOM 7760 C CA . GLU E 1 191 ? -34.457 19.353 -24.412 1.00 32.09 ? 172 GLU E CA 1 ATOM 7761 C C . GLU E 1 191 ? -34.493 19.973 -23.017 1.00 34.31 ? 172 GLU E C 1 ATOM 7762 O O . GLU E 1 191 ? -34.053 19.347 -22.040 1.00 34.21 ? 172 GLU E O 1 ATOM 7763 C CB . GLU E 1 191 ? -35.789 18.679 -24.762 1.00 39.32 ? 172 GLU E CB 1 ATOM 7764 C CG . GLU E 1 191 ? -36.161 17.486 -23.895 1.00 42.30 ? 172 GLU E CG 1 ATOM 7765 C CD . GLU E 1 191 ? -37.375 16.742 -24.444 1.00 50.88 ? 172 GLU E CD 1 ATOM 7766 O OE1 . GLU E 1 191 ? -38.035 17.314 -25.342 1.00 53.72 ? 172 GLU E OE1 1 ATOM 7767 O OE2 . GLU E 1 191 ? -37.661 15.599 -23.989 1.00 47.08 ? 172 GLU E OE2 1 ATOM 7768 N N . ILE E 1 192 ? -34.996 21.205 -22.934 1.00 32.60 ? 173 ILE E N 1 ATOM 7769 C CA . ILE E 1 192 ? -35.079 21.917 -21.653 1.00 37.37 ? 173 ILE E CA 1 ATOM 7770 C C . ILE E 1 192 ? -36.419 21.684 -20.950 1.00 29.50 ? 173 ILE E C 1 ATOM 7771 O O . ILE E 1 192 ? -37.476 21.901 -21.525 1.00 31.37 ? 173 ILE E O 1 ATOM 7772 C CB . ILE E 1 192 ? -34.829 23.440 -21.822 1.00 38.46 ? 173 ILE E CB 1 ATOM 7773 C CG1 . ILE E 1 192 ? -33.451 23.676 -22.437 1.00 32.90 ? 173 ILE E CG1 1 ATOM 7774 C CG2 . ILE E 1 192 ? -34.960 24.171 -20.482 1.00 30.93 ? 173 ILE E CG2 1 ATOM 7775 C CD1 . ILE E 1 192 ? -33.139 25.129 -22.687 1.00 34.82 ? 173 ILE E CD1 1 ATOM 7776 N N . LEU E 1 193 ? -36.357 21.236 -19.703 1.00 28.29 ? 174 LEU E N 1 ATOM 7777 C CA . LEU E 1 193 ? -37.559 20.993 -18.911 1.00 33.60 ? 174 LEU E CA 1 ATOM 7778 C C . LEU E 1 193 ? -37.930 22.244 -18.132 1.00 33.09 ? 174 LEU E C 1 ATOM 7779 O O . LEU E 1 193 ? -39.097 22.595 -18.048 1.00 51.89 ? 174 LEU E O 1 ATOM 7780 C CB . LEU E 1 193 ? -37.365 19.798 -17.967 1.00 24.71 ? 174 LEU E CB 1 ATOM 7781 C CG . LEU E 1 193 ? -36.869 18.555 -18.695 1.00 22.82 ? 174 LEU E CG 1 ATOM 7782 C CD1 . LEU E 1 193 ? -36.582 17.425 -17.738 1.00 27.24 ? 174 LEU E CD1 1 ATOM 7783 C CD2 . LEU E 1 193 ? -37.847 18.131 -19.796 1.00 23.45 ? 174 LEU E CD2 1 ATOM 7784 N N . ASP E 1 194 ? -36.934 22.921 -17.575 1.00 35.01 ? 175 ASP E N 1 ATOM 7785 C CA . ASP E 1 194 ? -37.177 24.145 -16.820 1.00 42.90 ? 175 ASP E CA 1 ATOM 7786 C C . ASP E 1 194 ? -35.915 24.985 -16.582 1.00 38.28 ? 175 ASP E C 1 ATOM 7787 O O . ASP E 1 194 ? -34.802 24.455 -16.490 1.00 34.26 ? 175 ASP E O 1 ATOM 7788 C CB . ASP E 1 194 ? -37.828 23.815 -15.471 1.00 37.45 ? 175 ASP E CB 1 ATOM 7789 C CG . ASP E 1 194 ? -38.544 25.013 -14.873 1.00 53.81 ? 175 ASP E CG 1 ATOM 7790 O OD1 . ASP E 1 194 ? -39.096 25.820 -15.663 1.00 55.55 ? 175 ASP E OD1 1 ATOM 7791 O OD2 . ASP E 1 194 ? -38.545 25.159 -13.628 1.00 61.71 ? 175 ASP E OD2 1 ATOM 7792 N N . VAL E 1 195 ? -36.101 26.296 -16.463 1.00 38.28 ? 176 VAL E N 1 ATOM 7793 C CA . VAL E 1 195 ? -35.007 27.194 -16.077 1.00 44.70 ? 176 VAL E CA 1 ATOM 7794 C C . VAL E 1 195 ? -35.393 28.121 -14.917 1.00 41.95 ? 176 VAL E C 1 ATOM 7795 O O . VAL E 1 195 ? -36.308 28.930 -15.059 1.00 35.77 ? 176 VAL E O 1 ATOM 7796 C CB . VAL E 1 195 ? -34.544 28.090 -17.251 1.00 36.12 ? 176 VAL E CB 1 ATOM 7797 C CG1 . VAL E 1 195 ? -33.462 29.023 -16.781 1.00 40.20 ? 176 VAL E CG1 1 ATOM 7798 C CG2 . VAL E 1 195 ? -34.026 27.265 -18.403 1.00 30.36 ? 176 VAL E CG2 1 ATOM 7799 N N . THR E 1 196 ? -34.686 28.015 -13.788 1.00 37.34 ? 177 THR E N 1 ATOM 7800 C CA . THR E 1 196 ? -34.935 28.890 -12.639 1.00 37.62 ? 177 THR E CA 1 ATOM 7801 C C . THR E 1 196 ? -33.711 29.748 -12.318 1.00 39.11 ? 177 THR E C 1 ATOM 7802 O O . THR E 1 196 ? -32.578 29.359 -12.620 1.00 39.30 ? 177 THR E O 1 ATOM 7803 C CB . THR E 1 196 ? -35.375 28.103 -11.382 1.00 42.02 ? 177 THR E CB 1 ATOM 7804 O OG1 . THR E 1 196 ? -34.330 27.201 -10.987 1.00 53.15 ? 177 THR E OG1 1 ATOM 7805 C CG2 . THR E 1 196 ? -36.648 27.318 -11.659 1.00 46.58 ? 177 THR E CG2 1 ATOM 7806 N N . GLN E 1 197 ? -33.949 30.911 -11.707 1.00 34.69 ? 178 GLN E N 1 ATOM 7807 C CA . GLN E 1 197 ? -32.888 31.862 -11.360 1.00 30.33 ? 178 GLN E CA 1 ATOM 7808 C C . GLN E 1 197 ? -32.991 32.243 -9.892 1.00 34.82 ? 178 GLN E C 1 ATOM 7809 O O . GLN E 1 197 ? -34.090 32.449 -9.378 1.00 51.52 ? 178 GLN E O 1 ATOM 7810 C CB . GLN E 1 197 ? -33.019 33.132 -12.206 1.00 31.42 ? 178 GLN E CB 1 ATOM 7811 C CG . GLN E 1 197 ? -33.072 32.885 -13.726 1.00 45.32 ? 178 GLN E CG 1 ATOM 7812 C CD . GLN E 1 197 ? -32.613 34.097 -14.570 1.00 60.25 ? 178 GLN E CD 1 ATOM 7813 O OE1 . GLN E 1 197 ? -32.817 35.251 -14.182 1.00 64.86 ? 178 GLN E OE1 1 ATOM 7814 N NE2 . GLN E 1 197 ? -31.986 33.826 -15.731 1.00 47.30 ? 178 GLN E NE2 1 ATOM 7815 N N . LYS E 1 198 ? -31.871 32.334 -9.195 1.00 28.30 ? 179 LYS E N 1 ATOM 7816 C CA . LYS E 1 198 ? -31.926 32.912 -7.861 1.00 27.25 ? 179 LYS E CA 1 ATOM 7817 C C . LYS E 1 198 ? -30.663 33.729 -7.565 1.00 30.28 ? 179 LYS E C 1 ATOM 7818 O O . LYS E 1 198 ? -29.620 33.519 -8.187 1.00 31.76 ? 179 LYS E O 1 ATOM 7819 C CB . LYS E 1 198 ? -32.188 31.845 -6.798 1.00 26.03 ? 179 LYS E CB 1 ATOM 7820 C CG . LYS E 1 198 ? -30.913 31.246 -6.213 1.00 45.95 ? 179 LYS E CG 1 ATOM 7821 C CD . LYS E 1 198 ? -31.209 30.347 -5.016 1.00 60.16 ? 179 LYS E CD 1 ATOM 7822 C CE . LYS E 1 198 ? -29.950 29.583 -4.565 1.00 59.04 ? 179 LYS E CE 1 ATOM 7823 N NZ . LYS E 1 198 ? -30.202 28.706 -3.351 1.00 63.08 ? 179 LYS E NZ 1 ATOM 7824 N N . LYS E 1 199 ? -30.764 34.671 -6.630 1.00 27.09 ? 180 LYS E N 1 ATOM 7825 C CA . LYS E 1 199 ? -29.639 35.536 -6.288 1.00 22.19 ? 180 LYS E CA 1 ATOM 7826 C C . LYS E 1 199 ? -28.928 35.144 -4.982 1.00 25.10 ? 180 LYS E C 1 ATOM 7827 O O . LYS E 1 199 ? -29.573 34.903 -3.957 1.00 29.86 ? 180 LYS E O 1 ATOM 7828 C CB . LYS E 1 199 ? -30.128 36.972 -6.193 1.00 29.40 ? 180 LYS E CB 1 ATOM 7829 C CG . LYS E 1 199 ? -29.159 37.906 -5.523 1.00 30.40 ? 180 LYS E CG 1 ATOM 7830 C CD . LYS E 1 199 ? -29.713 39.300 -5.509 1.00 35.67 ? 180 LYS E CD 1 ATOM 7831 C CE . LYS E 1 199 ? -28.783 40.228 -4.762 1.00 49.85 ? 180 LYS E CE 1 ATOM 7832 N NZ . LYS E 1 199 ? -29.197 41.671 -4.893 1.00 44.57 ? 180 LYS E NZ 1 ATOM 7833 N N . ASN E 1 200 ? -27.598 35.072 -5.021 1.00 27.08 ? 181 ASN E N 1 ATOM 7834 C CA . ASN E 1 200 ? -26.811 34.811 -3.815 1.00 28.42 ? 181 ASN E CA 1 ATOM 7835 C C . ASN E 1 200 ? -25.895 35.959 -3.422 1.00 29.71 ? 181 ASN E C 1 ATOM 7836 O O . ASN E 1 200 ? -25.478 36.748 -4.255 1.00 30.64 ? 181 ASN E O 1 ATOM 7837 C CB . ASN E 1 200 ? -25.960 33.547 -3.956 1.00 31.56 ? 181 ASN E CB 1 ATOM 7838 C CG . ASN E 1 200 ? -26.749 32.354 -4.468 1.00 38.69 ? 181 ASN E CG 1 ATOM 7839 O OD1 . ASN E 1 200 ? -27.511 31.712 -3.729 1.00 37.84 ? 181 ASN E OD1 1 ATOM 7840 N ND2 . ASN E 1 200 ? -26.552 32.035 -5.744 1.00 39.44 ? 181 ASN E ND2 1 ATOM 7841 N N . SER E 1 201 ? -25.579 36.040 -2.137 1.00 38.89 ? 182 SER E N 1 ATOM 7842 C CA . SER E 1 201 ? -24.651 37.042 -1.628 1.00 33.89 ? 182 SER E CA 1 ATOM 7843 C C . SER E 1 201 ? -23.662 36.306 -0.753 1.00 34.99 ? 182 SER E C 1 ATOM 7844 O O . SER E 1 201 ? -24.005 35.811 0.312 1.00 48.19 ? 182 SER E O 1 ATOM 7845 C CB . SER E 1 201 ? -25.387 38.112 -0.824 1.00 38.87 ? 182 SER E CB 1 ATOM 7846 O OG . SER E 1 201 ? -24.531 39.189 -0.495 1.00 46.35 ? 182 SER E OG 1 ATOM 7847 N N . VAL E 1 202 ? -22.428 36.227 -1.217 1.00 31.30 ? 183 VAL E N 1 ATOM 7848 C CA . VAL E 1 202 ? -21.409 35.382 -0.597 1.00 36.45 ? 183 VAL E CA 1 ATOM 7849 C C . VAL E 1 202 ? -20.242 36.167 0.011 1.00 38.51 ? 183 VAL E C 1 ATOM 7850 O O . VAL E 1 202 ? -19.736 37.117 -0.597 1.00 35.15 ? 183 VAL E O 1 ATOM 7851 C CB . VAL E 1 202 ? -20.834 34.455 -1.659 1.00 31.50 ? 183 VAL E CB 1 ATOM 7852 C CG1 . VAL E 1 202 ? -19.699 33.630 -1.103 1.00 23.74 ? 183 VAL E CG1 1 ATOM 7853 C CG2 . VAL E 1 202 ? -21.947 33.597 -2.233 1.00 47.14 ? 183 VAL E CG2 1 ATOM 7854 N N . THR E 1 203 ? -19.812 35.779 1.208 1.00 40.78 ? 184 THR E N 1 ATOM 7855 C CA . THR E 1 203 ? -18.590 36.358 1.772 1.00 43.85 ? 184 THR E CA 1 ATOM 7856 C C . THR E 1 203 ? -17.399 35.389 1.678 1.00 53.01 ? 184 THR E C 1 ATOM 7857 O O . THR E 1 203 ? -17.431 34.289 2.252 1.00 48.18 ? 184 THR E O 1 ATOM 7858 C CB . THR E 1 203 ? -18.769 36.814 3.222 1.00 41.24 ? 184 THR E CB 1 ATOM 7859 O OG1 . THR E 1 203 ? -19.657 37.943 3.274 1.00 25.39 ? 184 THR E OG1 1 ATOM 7860 C CG2 . THR E 1 203 ? -17.417 37.201 3.799 1.00 50.34 ? 184 THR E CG2 1 ATOM 7861 N N . TYR E 1 204 ? -16.357 35.801 0.948 1.00 60.19 ? 185 TYR E N 1 ATOM 7862 C CA . TYR E 1 204 ? -15.179 34.957 0.734 1.00 56.06 ? 185 TYR E CA 1 ATOM 7863 C C . TYR E 1 204 ? -14.139 35.170 1.830 1.00 72.30 ? 185 TYR E C 1 ATOM 7864 O O . TYR E 1 204 ? -14.187 36.170 2.569 1.00 68.43 ? 185 TYR E O 1 ATOM 7865 C CB . TYR E 1 204 ? -14.575 35.176 -0.658 1.00 49.26 ? 185 TYR E CB 1 ATOM 7866 C CG . TYR E 1 204 ? -15.506 34.790 -1.782 1.00 47.14 ? 185 TYR E CG 1 ATOM 7867 C CD1 . TYR E 1 204 ? -16.415 35.703 -2.295 1.00 47.09 ? 185 TYR E CD1 1 ATOM 7868 C CD2 . TYR E 1 204 ? -15.487 33.512 -2.321 1.00 45.59 ? 185 TYR E CD2 1 ATOM 7869 C CE1 . TYR E 1 204 ? -17.283 35.353 -3.322 1.00 55.64 ? 185 TYR E CE1 1 ATOM 7870 C CE2 . TYR E 1 204 ? -16.348 33.147 -3.352 1.00 46.19 ? 185 TYR E CE2 1 ATOM 7871 C CZ . TYR E 1 204 ? -17.247 34.073 -3.849 1.00 53.17 ? 185 TYR E CZ 1 ATOM 7872 O OH . TYR E 1 204 ? -18.120 33.737 -4.871 1.00 58.79 ? 185 TYR E OH 1 ATOM 7873 N N . SER E 1 205 ? -13.208 34.217 1.930 1.00 80.18 ? 186 SER E N 1 ATOM 7874 C CA . SER E 1 205 ? -12.172 34.210 2.975 1.00 84.70 ? 186 SER E CA 1 ATOM 7875 C C . SER E 1 205 ? -11.162 35.362 2.859 1.00 81.26 ? 186 SER E C 1 ATOM 7876 O O . SER E 1 205 ? -10.460 35.685 3.819 1.00 78.63 ? 186 SER E O 1 ATOM 7877 C CB . SER E 1 205 ? -11.433 32.869 2.979 1.00 74.28 ? 186 SER E CB 1 ATOM 7878 O OG . SER E 1 205 ? -12.327 31.803 3.232 1.00 70.75 ? 186 SER E OG 1 ATOM 7879 N N . CYS E 1 206 ? -11.124 35.986 1.685 1.00 79.76 ? 187 CYS E N 1 ATOM 7880 C CA A CYS E 1 206 ? -10.196 37.087 1.393 0.38 78.81 ? 187 CYS E CA 1 ATOM 7881 C CA B CYS E 1 206 ? -10.190 37.058 1.400 0.62 78.46 ? 187 CYS E CA 1 ATOM 7882 C C . CYS E 1 206 ? -10.605 38.427 2.023 1.00 82.97 ? 187 CYS E C 1 ATOM 7883 O O . CYS E 1 206 ? -9.781 39.121 2.631 1.00 84.52 ? 187 CYS E O 1 ATOM 7884 C CB A CYS E 1 206 ? -9.984 37.250 -0.132 0.38 75.53 ? 187 CYS E CB 1 ATOM 7885 C CB B CYS E 1 206 ? -10.021 37.126 -0.127 0.62 75.87 ? 187 CYS E CB 1 ATOM 7886 S SG A CYS E 1 206 ? -11.268 38.166 -1.081 0.38 44.85 ? 187 CYS E SG 1 ATOM 7887 S SG B CYS E 1 206 ? -10.275 35.485 -0.944 0.62 52.07 ? 187 CYS E SG 1 ATOM 7888 N N . CYS E 1 207 ? -11.883 38.794 1.895 1.00 79.13 ? 188 CYS E N 1 ATOM 7889 C CA . CYS E 1 207 ? -12.364 40.144 2.235 1.00 77.49 ? 188 CYS E CA 1 ATOM 7890 C C . CYS E 1 207 ? -13.637 40.145 3.109 1.00 82.64 ? 188 CYS E C 1 ATOM 7891 O O . CYS E 1 207 ? -14.414 39.181 3.085 1.00 87.17 ? 188 CYS E O 1 ATOM 7892 C CB . CYS E 1 207 ? -12.630 40.901 0.921 1.00 78.07 ? 188 CYS E CB 1 ATOM 7893 S SG . CYS E 1 207 ? -12.020 39.999 -0.585 1.00 83.57 ? 188 CYS E SG 1 ATOM 7894 N N . PRO E 1 208 ? -13.863 41.228 3.879 1.00 78.67 ? 189 PRO E N 1 ATOM 7895 C CA . PRO E 1 208 ? -15.044 41.361 4.759 1.00 78.37 ? 189 PRO E CA 1 ATOM 7896 C C . PRO E 1 208 ? -16.329 41.802 4.032 1.00 76.09 ? 189 PRO E C 1 ATOM 7897 O O . PRO E 1 208 ? -17.398 41.907 4.650 1.00 67.39 ? 189 PRO E O 1 ATOM 7898 C CB . PRO E 1 208 ? -14.623 42.468 5.732 1.00 75.23 ? 189 PRO E CB 1 ATOM 7899 C CG . PRO E 1 208 ? -13.742 43.349 4.892 1.00 82.98 ? 189 PRO E CG 1 ATOM 7900 C CD . PRO E 1 208 ? -12.966 42.396 3.984 1.00 75.25 ? 189 PRO E CD 1 ATOM 7901 N N . GLU E 1 209 ? -16.208 42.079 2.735 1.00 73.35 ? 190 GLU E N 1 ATOM 7902 C CA . GLU E 1 209 ? -17.318 42.564 1.923 1.00 49.15 ? 190 GLU E CA 1 ATOM 7903 C C . GLU E 1 209 ? -18.060 41.396 1.276 1.00 46.34 ? 190 GLU E C 1 ATOM 7904 O O . GLU E 1 209 ? -17.486 40.309 1.086 1.00 49.47 ? 190 GLU E O 1 ATOM 7905 C CB . GLU E 1 209 ? -16.765 43.474 0.835 1.00 42.11 ? 190 GLU E CB 1 ATOM 7906 C CG . GLU E 1 209 ? -15.715 44.452 1.319 1.00 54.79 ? 190 GLU E CG 1 ATOM 7907 C CD . GLU E 1 209 ? -16.331 45.654 2.016 1.00 76.40 ? 190 GLU E CD 1 ATOM 7908 O OE1 . GLU E 1 209 ? -17.576 45.675 2.175 1.00 80.21 ? 190 GLU E OE1 1 ATOM 7909 O OE2 . GLU E 1 209 ? -15.575 46.579 2.398 1.00 82.54 1 190 GLU E OE2 1 ATOM 7910 N N . ALA E 1 210 ? -19.325 41.619 0.922 1.00 31.66 ? 191 ALA E N 1 ATOM 7911 C CA . ALA E 1 210 ? -20.111 40.589 0.238 1.00 30.59 ? 191 ALA E CA 1 ATOM 7912 C C . ALA E 1 210 ? -20.067 40.738 -1.287 1.00 30.57 ? 191 ALA E C 1 ATOM 7913 O O . ALA E 1 210 ? -20.071 41.849 -1.818 1.00 24.44 ? 191 ALA E O 1 ATOM 7914 C CB . ALA E 1 210 ? -21.533 40.622 0.714 1.00 26.82 ? 191 ALA E CB 1 ATOM 7915 N N . TYR E 1 211 ? -20.043 39.612 -1.988 1.00 30.62 ? 192 TYR E N 1 ATOM 7916 C CA . TYR E 1 211 ? -20.065 39.621 -3.447 1.00 27.78 ? 192 TYR E CA 1 ATOM 7917 C C . TYR E 1 211 ? -21.334 38.956 -3.991 1.00 26.41 ? 192 TYR E C 1 ATOM 7918 O O . TYR E 1 211 ? -21.558 37.771 -3.766 1.00 28.32 ? 192 TYR E O 1 ATOM 7919 C CB . TYR E 1 211 ? -18.829 38.904 -3.989 1.00 25.91 ? 192 TYR E CB 1 ATOM 7920 C CG . TYR E 1 211 ? -17.564 39.678 -3.771 1.00 28.07 ? 192 TYR E CG 1 ATOM 7921 C CD1 . TYR E 1 211 ? -16.947 39.691 -2.535 1.00 33.57 ? 192 TYR E CD1 1 ATOM 7922 C CD2 . TYR E 1 211 ? -16.989 40.415 -4.801 1.00 34.74 ? 192 TYR E CD2 1 ATOM 7923 C CE1 . TYR E 1 211 ? -15.781 40.412 -2.319 1.00 37.42 ? 192 TYR E CE1 1 ATOM 7924 C CE2 . TYR E 1 211 ? -15.816 41.138 -4.604 1.00 32.99 ? 192 TYR E CE2 1 ATOM 7925 C CZ . TYR E 1 211 ? -15.219 41.129 -3.354 1.00 36.14 ? 192 TYR E CZ 1 ATOM 7926 O OH . TYR E 1 211 ? -14.063 41.837 -3.124 1.00 42.25 ? 192 TYR E OH 1 ATOM 7927 N N . GLU E 1 212 ? -22.160 39.705 -4.711 1.00 20.28 ? 193 GLU E N 1 ATOM 7928 C CA . GLU E 1 212 ? -23.377 39.127 -5.250 1.00 20.47 ? 193 GLU E CA 1 ATOM 7929 C C . GLU E 1 212 ? -23.110 38.300 -6.511 1.00 25.39 ? 193 GLU E C 1 ATOM 7930 O O . GLU E 1 212 ? -22.204 38.613 -7.294 1.00 26.71 ? 193 GLU E O 1 ATOM 7931 C CB . GLU E 1 212 ? -24.411 40.211 -5.536 1.00 22.54 ? 193 GLU E CB 1 ATOM 7932 C CG . GLU E 1 212 ? -24.754 41.062 -4.333 1.00 30.66 ? 193 GLU E CG 1 ATOM 7933 C CD . GLU E 1 212 ? -25.890 42.049 -4.615 1.00 47.53 ? 193 GLU E CD 1 ATOM 7934 O OE1 . GLU E 1 212 ? -26.413 42.073 -5.768 1.00 42.84 ? 193 GLU E OE1 1 ATOM 7935 O OE2 . GLU E 1 212 ? -26.266 42.798 -3.677 1.00 48.36 ? 193 GLU E OE2 1 ATOM 7936 N N . ASP E 1 213 ? -23.906 37.243 -6.689 1.00 24.95 ? 194 ASP E N 1 ATOM 7937 C CA . ASP E 1 213 ? -23.964 36.489 -7.939 1.00 20.01 ? 194 ASP E CA 1 ATOM 7938 C C . ASP E 1 213 ? -25.373 35.973 -8.244 1.00 23.69 ? 194 ASP E C 1 ATOM 7939 O O . ASP E 1 213 ? -26.243 35.934 -7.377 1.00 26.21 ? 194 ASP E O 1 ATOM 7940 C CB . ASP E 1 213 ? -23.005 35.326 -7.903 1.00 24.61 ? 194 ASP E CB 1 ATOM 7941 C CG . ASP E 1 213 ? -23.248 34.415 -6.704 1.00 45.35 ? 194 ASP E CG 1 ATOM 7942 O OD1 . ASP E 1 213 ? -24.165 33.548 -6.771 1.00 48.41 ? 194 ASP E OD1 1 ATOM 7943 O OD2 . ASP E 1 213 ? -22.515 34.574 -5.693 1.00 46.44 ? 194 ASP E OD2 1 ATOM 7944 N N . VAL E 1 214 ? -25.594 35.592 -9.495 1.00 23.82 ? 195 VAL E N 1 ATOM 7945 C CA . VAL E 1 214 ? -26.835 34.951 -9.891 1.00 23.99 ? 195 VAL E CA 1 ATOM 7946 C C . VAL E 1 214 ? -26.580 33.480 -10.218 1.00 31.71 ? 195 VAL E C 1 ATOM 7947 O O . VAL E 1 214 ? -25.609 33.143 -10.910 1.00 28.84 ? 195 VAL E O 1 ATOM 7948 C CB . VAL E 1 214 ? -27.461 35.666 -11.089 1.00 24.55 ? 195 VAL E CB 1 ATOM 7949 C CG1 . VAL E 1 214 ? -28.638 34.872 -11.643 1.00 28.28 ? 195 VAL E CG1 1 ATOM 7950 C CG2 . VAL E 1 214 ? -27.904 37.059 -10.678 1.00 32.22 ? 195 VAL E CG2 1 ATOM 7951 N N . GLU E 1 215 ? -27.431 32.608 -9.676 1.00 31.50 ? 196 GLU E N 1 ATOM 7952 C CA . GLU E 1 215 ? -27.345 31.181 -9.938 1.00 32.44 ? 196 GLU E CA 1 ATOM 7953 C C . GLU E 1 215 ? -28.470 30.807 -10.893 1.00 29.89 ? 196 GLU E C 1 ATOM 7954 O O . GLU E 1 215 ? -29.645 31.048 -10.602 1.00 31.64 ? 196 GLU E O 1 ATOM 7955 C CB . GLU E 1 215 ? -27.470 30.390 -8.633 1.00 38.00 ? 196 GLU E CB 1 ATOM 7956 C CG . GLU E 1 215 ? -26.376 29.336 -8.403 1.00 47.67 ? 196 GLU E CG 1 ATOM 7957 C CD . GLU E 1 215 ? -26.469 28.654 -7.022 1.00 67.78 ? 196 GLU E CD 1 ATOM 7958 O OE1 . GLU E 1 215 ? -27.596 28.232 -6.633 1.00 51.33 ? 196 GLU E OE1 1 ATOM 7959 O OE2 . GLU E 1 215 ? -25.412 28.557 -6.332 1.00 71.32 ? 196 GLU E OE2 1 ATOM 7960 N N . VAL E 1 216 ? -28.121 30.226 -12.035 1.00 24.74 ? 197 VAL E N 1 ATOM 7961 C CA . VAL E 1 216 ? -29.139 29.824 -12.999 1.00 26.02 ? 197 VAL E CA 1 ATOM 7962 C C . VAL E 1 216 ? -29.200 28.313 -13.098 1.00 23.84 ? 197 VAL E C 1 ATOM 7963 O O . VAL E 1 216 ? -28.243 27.674 -13.532 1.00 21.24 ? 197 VAL E O 1 ATOM 7964 C CB . VAL E 1 216 ? -28.866 30.421 -14.392 1.00 31.28 ? 197 VAL E CB 1 ATOM 7965 C CG1 . VAL E 1 216 ? -29.891 29.924 -15.397 1.00 25.98 ? 197 VAL E CG1 1 ATOM 7966 C CG2 . VAL E 1 216 ? -28.863 31.929 -14.335 1.00 25.34 ? 197 VAL E CG2 1 ATOM 7967 N N . SER E 1 217 ? -30.335 27.750 -12.698 1.00 32.08 ? 198 SER E N 1 ATOM 7968 C CA . SER E 1 217 ? -30.523 26.296 -12.702 1.00 34.81 ? 198 SER E CA 1 ATOM 7969 C C . SER E 1 217 ? -31.174 25.828 -13.998 1.00 28.82 ? 198 SER E C 1 ATOM 7970 O O . SER E 1 217 ? -32.280 26.252 -14.356 1.00 34.90 ? 198 SER E O 1 ATOM 7971 C CB . SER E 1 217 ? -31.368 25.862 -11.502 1.00 36.61 ? 198 SER E CB 1 ATOM 7972 O OG . SER E 1 217 ? -30.789 26.330 -10.302 1.00 42.69 ? 198 SER E OG 1 ATOM 7973 N N . LEU E 1 218 ? -30.483 24.947 -14.697 1.00 23.89 ? 199 LEU E N 1 ATOM 7974 C CA . LEU E 1 218 ? -30.963 24.469 -15.980 1.00 27.04 ? 199 LEU E CA 1 ATOM 7975 C C . LEU E 1 218 ? -31.351 23.006 -15.864 1.00 28.41 ? 199 LEU E C 1 ATOM 7976 O O . LEU E 1 218 ? -30.490 22.149 -15.691 1.00 29.00 ? 199 LEU E O 1 ATOM 7977 C CB . LEU E 1 218 ? -29.876 24.644 -17.037 1.00 27.12 ? 199 LEU E CB 1 ATOM 7978 C CG . LEU E 1 218 ? -30.134 23.932 -18.363 1.00 29.25 ? 199 LEU E CG 1 ATOM 7979 C CD1 . LEU E 1 218 ? -31.403 24.505 -19.010 1.00 33.31 ? 199 LEU E CD1 1 ATOM 7980 C CD2 . LEU E 1 218 ? -28.914 24.031 -19.304 1.00 20.00 ? 199 LEU E CD2 1 ATOM 7981 N N . ASN E 1 219 ? -32.650 22.720 -15.941 1.00 32.25 ? 200 ASN E N 1 ATOM 7982 C CA . ASN E 1 219 ? -33.126 21.338 -15.903 1.00 30.29 ? 200 ASN E CA 1 ATOM 7983 C C . ASN E 1 219 ? -33.359 20.804 -17.315 1.00 23.87 ? 200 ASN E C 1 ATOM 7984 O O . ASN E 1 219 ? -34.210 21.310 -18.035 1.00 26.46 ? 200 ASN E O 1 ATOM 7985 C CB . ASN E 1 219 ? -34.397 21.245 -15.050 1.00 36.76 ? 200 ASN E CB 1 ATOM 7986 C CG . ASN E 1 219 ? -34.855 19.797 -14.814 1.00 40.03 ? 200 ASN E CG 1 ATOM 7987 O OD1 . ASN E 1 219 ? -36.050 19.497 -14.865 1.00 41.17 ? 200 ASN E OD1 1 ATOM 7988 N ND2 . ASN E 1 219 ? -33.903 18.897 -14.567 1.00 38.50 ? 200 ASN E ND2 1 ATOM 7989 N N . PHE E 1 220 ? -32.591 19.793 -17.715 1.00 20.51 ? 201 PHE E N 1 ATOM 7990 C CA . PHE E 1 220 ? -32.625 19.300 -19.098 1.00 25.47 ? 201 PHE E CA 1 ATOM 7991 C C . PHE E 1 220 ? -32.410 17.789 -19.155 1.00 29.62 ? 201 PHE E C 1 ATOM 7992 O O . PHE E 1 220 ? -31.879 17.195 -18.200 1.00 32.14 ? 201 PHE E O 1 ATOM 7993 C CB . PHE E 1 220 ? -31.548 20.004 -19.942 1.00 26.33 ? 201 PHE E CB 1 ATOM 7994 C CG . PHE E 1 220 ? -30.139 19.558 -19.627 1.00 23.69 ? 201 PHE E CG 1 ATOM 7995 C CD1 . PHE E 1 220 ? -29.548 19.873 -18.406 1.00 25.31 ? 201 PHE E CD1 1 ATOM 7996 C CD2 . PHE E 1 220 ? -29.404 18.813 -20.543 1.00 23.37 ? 201 PHE E CD2 1 ATOM 7997 C CE1 . PHE E 1 220 ? -28.253 19.452 -18.099 1.00 19.19 ? 201 PHE E CE1 1 ATOM 7998 C CE2 . PHE E 1 220 ? -28.105 18.390 -20.243 1.00 19.07 ? 201 PHE E CE2 1 ATOM 7999 C CZ . PHE E 1 220 ? -27.533 18.714 -19.025 1.00 16.70 ? 201 PHE E CZ 1 ATOM 8000 N N . ARG E 1 221 ? -32.816 17.161 -20.263 1.00 28.32 ? 202 ARG E N 1 ATOM 8001 C CA . ARG E 1 221 ? -32.554 15.715 -20.465 1.00 31.70 ? 202 ARG E CA 1 ATOM 8002 C C . ARG E 1 221 ? -32.348 15.368 -21.924 1.00 33.41 ? 202 ARG E C 1 ATOM 8003 O O . ARG E 1 221 ? -32.621 16.188 -22.817 1.00 38.56 ? 202 ARG E O 1 ATOM 8004 C CB . ARG E 1 221 ? -33.694 14.854 -19.924 1.00 29.10 ? 202 ARG E CB 1 ATOM 8005 C CG . ARG E 1 221 ? -35.013 15.169 -20.589 1.00 26.61 ? 202 ARG E CG 1 ATOM 8006 C CD . ARG E 1 221 ? -35.862 13.948 -20.743 1.00 41.56 ? 202 ARG E CD 1 ATOM 8007 N NE . ARG E 1 221 ? -37.131 14.284 -21.380 1.00 39.15 ? 202 ARG E NE 1 ATOM 8008 C CZ . ARG E 1 221 ? -38.286 14.407 -20.733 1.00 40.43 ? 202 ARG E CZ 1 ATOM 8009 N NH1 . ARG E 1 221 ? -38.341 14.197 -19.421 1.00 34.87 ? 202 ARG E NH1 1 ATOM 8010 N NH2 . ARG E 1 221 ? -39.387 14.735 -21.406 1.00 36.01 ? 202 ARG E NH2 1 ATOM 8011 N N . LYS E 1 222 ? -31.887 14.142 -22.157 1.00 32.75 ? 203 LYS E N 1 ATOM 8012 C CA . LYS E 1 222 ? -31.726 13.609 -23.507 1.00 33.23 ? 203 LYS E CA 1 ATOM 8013 C C . LYS E 1 222 ? -33.091 13.262 -24.092 1.00 37.07 ? 203 LYS E C 1 ATOM 8014 O O . LYS E 1 222 ? -33.972 12.761 -23.382 1.00 40.72 ? 203 LYS E O 1 ATOM 8015 C CB . LYS E 1 222 ? -30.829 12.368 -23.487 1.00 31.50 ? 203 LYS E CB 1 ATOM 8016 C CG . LYS E 1 222 ? -30.498 11.827 -24.859 1.00 34.58 ? 203 LYS E CG 1 ATOM 8017 C CD . LYS E 1 222 ? -29.491 10.698 -24.742 1.00 56.01 ? 203 LYS E CD 1 ATOM 8018 C CE . LYS E 1 222 ? -29.099 10.127 -26.104 1.00 67.79 ? 203 LYS E CE 1 ATOM 8019 N NZ . LYS E 1 222 ? -28.157 8.977 -25.939 1.00 74.39 ? 203 LYS E NZ 1 ATOM 8020 N N . LYS E 1 223 ? -33.268 13.541 -25.381 1.00 37.72 ? 204 LYS E N 1 ATOM 8021 C CA . LYS E 1 223 ? -34.517 13.246 -26.085 1.00 41.66 ? 204 LYS E CA 1 ATOM 8022 C C . LYS E 1 223 ? -34.751 11.739 -26.303 1.00 41.16 ? 204 LYS E C 1 ATOM 8023 O O . LYS E 1 223 ? -33.804 10.954 -26.391 1.00 44.65 ? 204 LYS E O 1 ATOM 8024 C CB . LYS E 1 223 ? -34.536 13.963 -27.433 1.00 40.11 ? 204 LYS E CB 1 ATOM 8025 C CG . LYS E 1 223 ? -34.805 15.462 -27.386 1.00 36.46 ? 204 LYS E CG 1 ATOM 8026 C CD . LYS E 1 223 ? -34.549 16.042 -28.778 1.00 28.28 ? 204 LYS E CD 1 ATOM 8027 C CE . LYS E 1 223 ? -35.289 17.334 -29.015 1.00 34.26 ? 204 LYS E CE 1 ATOM 8028 N NZ . LYS E 1 223 ? -35.275 17.711 -30.462 1.00 37.85 ? 204 LYS E NZ 1 HETATM 8029 C C1 . 09P F 2 . ? 14.282 30.539 -15.249 1.00 26.02 ? 211 09P A C1 1 HETATM 8030 N N1 . 09P F 2 . ? 14.188 31.374 -14.017 1.00 29.60 ? 211 09P A N1 1 HETATM 8031 C C2 . 09P F 2 . ? 15.301 31.340 -13.027 1.00 30.14 ? 211 09P A C2 1 HETATM 8032 C C3 . 09P F 2 . ? 16.536 32.127 -13.510 1.00 32.01 ? 211 09P A C3 1 HETATM 8033 C C4 . 09P F 2 . ? 17.091 31.607 -14.843 1.00 34.82 ? 211 09P A C4 1 HETATM 8034 N N2 . 09P F 2 . ? 16.218 32.090 -15.923 1.00 26.50 ? 211 09P A N2 1 HETATM 8035 C C5 . 09P F 2 . ? 15.261 31.036 -16.345 1.00 22.81 ? 211 09P A C5 1 HETATM 8036 C C6 . 09P F 2 . ? 16.900 35.630 -18.066 1.00 26.31 ? 211 09P A C6 1 HETATM 8037 C C7 . 09P F 2 . ? 17.836 35.244 -17.091 1.00 40.17 ? 211 09P A C7 1 HETATM 8038 C C8 . 09P F 2 . ? 17.602 34.039 -16.354 1.00 37.54 ? 211 09P A C8 1 HETATM 8039 C C9 . 09P F 2 . ? 16.455 33.247 -16.607 1.00 29.90 ? 211 09P A C9 1 HETATM 8040 C C10 . 09P F 2 . ? 15.603 33.756 -17.626 1.00 32.12 ? 211 09P A C10 1 HETATM 8041 N N3 . 09P F 2 . ? 15.812 34.899 -18.333 1.00 32.68 ? 211 09P A N3 1 HETATM 8042 O O1 . 09P F 2 . ? 18.909 36.088 -16.867 1.00 48.20 ? 211 09P A O1 1 HETATM 8043 C C11 . 09P F 2 . ? 18.868 36.750 -15.598 1.00 41.81 ? 211 09P A C11 1 HETATM 8044 C C12 . 09P F 2 . ? 20.272 36.748 -15.013 1.00 58.36 ? 211 09P A C12 1 HETATM 8045 C C1 . 09P G 2 . ? 15.241 30.417 -44.505 1.00 24.26 ? 211 09P B C1 1 HETATM 8046 N N1 . 09P G 2 . ? 16.495 30.942 -43.909 1.00 25.54 ? 211 09P B N1 1 HETATM 8047 C C2 . 09P G 2 . ? 17.753 30.815 -44.694 1.00 30.21 ? 211 09P B C2 1 HETATM 8048 C C3 . 09P G 2 . ? 17.820 31.837 -45.849 1.00 29.22 ? 211 09P B C3 1 HETATM 8049 C C4 . 09P G 2 . ? 16.603 31.809 -46.785 1.00 22.28 ? 211 09P B C4 1 HETATM 8050 N N2 . 09P G 2 . ? 15.434 32.392 -46.109 1.00 27.20 ? 211 09P B N2 1 HETATM 8051 C C5 . 09P G 2 . ? 14.546 31.356 -45.525 1.00 24.52 ? 211 09P B C5 1 HETATM 8052 C C6 . 09P G 2 . ? 13.980 36.145 -47.028 1.00 37.31 ? 211 09P B C6 1 HETATM 8053 C C7 . 09P G 2 . ? 15.270 35.827 -47.518 1.00 38.95 ? 211 09P B C7 1 HETATM 8054 C C8 . 09P G 2 . ? 15.772 34.533 -47.196 1.00 33.69 ? 211 09P B C8 1 HETATM 8055 C C9 . 09P G 2 . ? 14.986 33.638 -46.417 1.00 33.51 ? 211 09P B C9 1 HETATM 8056 C C10 . 09P G 2 . ? 13.714 34.109 -45.994 1.00 31.69 ? 211 09P B C10 1 HETATM 8057 N N3 . 09P G 2 . ? 13.210 35.329 -46.291 1.00 30.52 ? 211 09P B N3 1 HETATM 8058 O O1 . 09P G 2 . ? 15.935 36.801 -48.273 1.00 50.51 ? 211 09P B O1 1 HETATM 8059 C C11 . 09P G 2 . ? 17.175 36.523 -48.934 1.00 44.00 ? 211 09P B C11 1 HETATM 8060 C C12 . 09P G 2 . ? 16.926 36.570 -50.439 1.00 38.14 ? 211 09P B C12 1 HETATM 8061 C C1 . 09P H 2 . ? -11.634 35.516 -55.001 1.00 24.53 ? 211 09P C C1 1 HETATM 8062 N N1 . 09P H 2 . ? -10.759 36.181 -55.991 1.00 22.64 ? 211 09P C N1 1 HETATM 8063 C C2 . 09P H 2 . ? -11.332 36.605 -57.277 1.00 20.21 ? 211 09P C C2 1 HETATM 8064 C C3 . 09P H 2 . ? -12.359 37.720 -57.070 1.00 22.01 ? 211 09P C C3 1 HETATM 8065 C C4 . 09P H 2 . ? -13.483 37.247 -56.143 1.00 23.38 ? 211 09P C C4 1 HETATM 8066 N N2 . 09P H 2 . ? -13.117 37.554 -54.746 1.00 25.82 ? 211 09P C N2 1 HETATM 8067 C C5 . 09P H 2 . ? -12.345 36.501 -54.053 1.00 23.62 ? 211 09P C C5 1 HETATM 8068 C C6 . 09P H 2 . ? -13.854 41.147 -52.920 1.00 26.04 ? 211 09P C C6 1 HETATM 8069 C C7 . 09P H 2 . ? -13.969 41.115 -54.324 1.00 28.97 ? 211 09P C C7 1 HETATM 8070 C C8 . 09P H 2 . ? -13.715 39.880 -54.965 1.00 27.93 ? 211 09P C C8 1 HETATM 8071 C C9 . 09P H 2 . ? -13.361 38.745 -54.177 1.00 25.83 ? 211 09P C C9 1 HETATM 8072 C C10 . 09P H 2 . ? -13.272 38.902 -52.778 1.00 20.76 ? 211 09P C C10 1 HETATM 8073 N N3 . 09P H 2 . ? -13.522 40.079 -52.172 1.00 26.58 ? 211 09P C N3 1 HETATM 8074 O O1 . 09P H 2 . ? -14.320 42.281 -54.976 1.00 44.48 ? 211 09P C O1 1 HETATM 8075 C C11 . 09P H 2 . ? -14.315 42.331 -56.403 1.00 42.90 ? 211 09P C C11 1 HETATM 8076 C C12 . 09P H 2 . ? -15.391 43.324 -56.830 1.00 36.76 ? 211 09P C C12 1 HETATM 8077 C C1 . 09P I 2 . ? -29.805 38.965 -31.464 1.00 19.29 ? 211 09P D C1 1 HETATM 8078 N N1 . 09P I 2 . ? -30.316 39.838 -32.545 1.00 20.59 ? 211 09P D N1 1 HETATM 8079 C C2 . 09P I 2 . ? -31.747 40.212 -32.456 1.00 21.88 ? 211 09P D C2 1 HETATM 8080 C C3 . 09P I 2 . ? -32.021 41.142 -31.255 1.00 28.14 ? 211 09P D C3 1 HETATM 8081 C C4 . 09P I 2 . ? -31.519 40.651 -29.886 1.00 19.14 ? 211 09P D C4 1 HETATM 8082 N N2 . 09P I 2 . ? -30.065 40.884 -29.748 1.00 23.53 ? 211 09P D N2 1 HETATM 8083 C C5 . 09P I 2 . ? -29.257 39.733 -30.240 1.00 24.43 ? 211 09P D C5 1 HETATM 8084 C C6 . 09P I 2 . ? -28.306 44.237 -27.983 1.00 21.96 ? 211 09P D C6 1 HETATM 8085 C C7 . 09P I 2 . ? -29.695 44.262 -28.193 1.00 24.04 ? 211 09P D C7 1 HETATM 8086 C C8 . 09P I 2 . ? -30.293 43.122 -28.794 1.00 29.63 ? 211 09P D C8 1 HETATM 8087 C C9 . 09P I 2 . ? -29.508 41.997 -29.166 1.00 28.93 ? 211 09P D C9 1 HETATM 8088 C C10 . 09P I 2 . ? -28.117 42.127 -28.885 1.00 27.84 ? 211 09P D C10 1 HETATM 8089 N N3 . 09P I 2 . ? -27.527 43.209 -28.315 1.00 20.27 ? 211 09P D N3 1 HETATM 8090 O O1 . 09P I 2 . ? -30.377 45.398 -27.805 1.00 35.12 ? 211 09P D O1 1 HETATM 8091 C C11 . 09P I 2 . ? -31.727 45.634 -28.228 1.00 37.54 ? 211 09P D C11 1 HETATM 8092 C C12 . 09P I 2 . ? -32.518 46.118 -27.012 1.00 32.01 ? 211 09P D C12 1 HETATM 8093 C C1 . NAG J 3 . ? -14.380 65.862 -61.881 1.00 44.52 ? 1206 NAG D C1 1 HETATM 8094 C C2 . NAG J 3 . ? -15.314 67.029 -61.552 1.00 49.39 ? 1206 NAG D C2 1 HETATM 8095 C C3 . NAG J 3 . ? -15.589 67.650 -62.903 1.00 50.82 ? 1206 NAG D C3 1 HETATM 8096 C C4 . NAG J 3 . ? -14.319 68.168 -63.561 1.00 50.83 ? 1206 NAG D C4 1 HETATM 8097 C C5 . NAG J 3 . ? -13.215 67.111 -63.743 1.00 50.10 ? 1206 NAG D C5 1 HETATM 8098 C C6 . NAG J 3 . ? -11.853 67.811 -64.052 1.00 50.28 ? 1206 NAG D C6 1 HETATM 8099 C C7 . NAG J 3 . ? -17.219 66.889 -59.808 1.00 51.12 ? 1206 NAG D C7 1 HETATM 8100 C C8 . NAG J 3 . ? -16.481 67.584 -58.699 1.00 53.33 ? 1206 NAG D C8 1 HETATM 8101 N N2 . NAG J 3 . ? -16.625 66.678 -61.008 1.00 51.97 ? 1206 NAG D N2 1 HETATM 8102 O O3 . NAG J 3 . ? -16.401 68.744 -62.620 1.00 52.02 ? 1206 NAG D O3 1 HETATM 8103 O O4 . NAG J 3 . ? -14.603 68.937 -64.713 1.00 52.34 ? 1206 NAG D O4 1 HETATM 8104 O O5 . NAG J 3 . ? -13.190 66.227 -62.622 1.00 47.14 ? 1206 NAG D O5 1 HETATM 8105 O O6 . NAG J 3 . ? -10.599 67.211 -63.710 1.00 54.69 ? 1206 NAG D O6 1 HETATM 8106 O O7 . NAG J 3 . ? -18.364 66.519 -59.536 1.00 53.65 ? 1206 NAG D O7 1 HETATM 8107 C C1 . 09P K 2 . ? -13.788 35.871 -6.779 1.00 26.45 ? 211 09P E C1 1 HETATM 8108 N N1 . 09P K 2 . ? -14.673 37.051 -6.680 1.00 32.04 ? 211 09P E N1 1 HETATM 8109 C C2 . 09P K 2 . ? -15.067 37.512 -5.321 1.00 35.59 ? 211 09P E C2 1 HETATM 8110 C C3 . 09P K 2 . ? -13.891 38.158 -4.567 1.00 31.66 ? 211 09P E C3 1 HETATM 8111 C C4 . 09P K 2 . ? -12.662 37.240 -4.563 1.00 31.24 ? 211 09P E C4 1 HETATM 8112 N N2 . 09P K 2 . ? -11.973 37.365 -5.865 1.00 40.75 ? 211 09P E N2 1 HETATM 8113 C C5 . 09P K 2 . ? -12.304 36.272 -6.820 1.00 23.51 ? 211 09P E C5 1 HETATM 8114 C C6 . 09P K 2 . ? -9.365 40.423 -6.879 1.00 27.92 ? 211 09P E C6 1 HETATM 8115 C C7 . 09P K 2 . ? -9.878 40.446 -5.568 1.00 37.86 ? 211 09P E C7 1 HETATM 8116 C C8 . 09P K 2 . ? -10.774 39.394 -5.212 1.00 38.65 ? 211 09P E C8 1 HETATM 8117 C C9 . 09P K 2 . ? -11.118 38.388 -6.165 1.00 39.57 ? 211 09P E C9 1 HETATM 8118 C C10 . 09P K 2 . ? -10.512 38.504 -7.445 1.00 30.90 ? 211 09P E C10 1 HETATM 8119 N N3 . 09P K 2 . ? -9.666 39.490 -7.790 1.00 25.65 ? 211 09P E N3 1 HETATM 8120 O O1 . 09P K 2 . ? -9.484 41.486 -4.732 1.00 43.52 ? 211 09P E O1 1 HETATM 8121 C C11 . 09P K 2 . ? -10.111 41.671 -3.459 1.00 40.16 ? 211 09P E C11 1 HETATM 8122 C C12 . 09P K 2 . ? -9.041 42.086 -2.450 1.00 39.42 ? 211 09P E C12 1 HETATM 8123 O O . HOH L 4 . ? -13.327 51.271 -9.338 1.00 16.79 ? 2001 HOH A O 1 HETATM 8124 O O . HOH L 4 . ? -2.363 52.948 -22.898 1.00 43.21 ? 2002 HOH A O 1 HETATM 8125 O O . HOH L 4 . ? 2.290 50.017 -11.219 1.00 18.15 ? 2003 HOH A O 1 HETATM 8126 O O . HOH L 4 . ? 5.758 50.830 -10.538 1.00 22.07 ? 2004 HOH A O 1 HETATM 8127 O O . HOH L 4 . ? 3.982 44.706 -15.231 1.00 16.76 ? 2005 HOH A O 1 HETATM 8128 O O . HOH L 4 . ? 5.404 44.041 -0.965 1.00 21.53 ? 2006 HOH A O 1 HETATM 8129 O O . HOH L 4 . ? 2.615 40.680 0.374 1.00 27.01 ? 2007 HOH A O 1 HETATM 8130 O O . HOH L 4 . ? -11.690 13.520 -14.884 1.00 35.11 ? 2008 HOH A O 1 HETATM 8131 O O . HOH L 4 . ? 5.388 14.227 -17.125 1.00 26.48 ? 2009 HOH A O 1 HETATM 8132 O O . HOH L 4 . ? 2.008 47.114 -9.029 1.00 18.57 ? 2010 HOH A O 1 HETATM 8133 O O . HOH L 4 . ? 1.720 45.079 -16.470 1.00 21.93 ? 2011 HOH A O 1 HETATM 8134 O O . HOH L 4 . ? 7.295 42.254 -14.635 1.00 24.63 ? 2012 HOH A O 1 HETATM 8135 O O . HOH L 4 . ? 9.463 43.837 -14.466 1.00 15.88 ? 2013 HOH A O 1 HETATM 8136 O O . HOH L 4 . ? -2.611 26.769 -23.161 1.00 26.26 ? 2014 HOH A O 1 HETATM 8137 O O . HOH L 4 . ? -5.710 33.619 -21.035 1.00 23.00 ? 2015 HOH A O 1 HETATM 8138 O O . HOH L 4 . ? -10.326 41.179 -19.262 1.00 21.32 ? 2016 HOH A O 1 HETATM 8139 O O . HOH L 4 . ? -8.166 39.671 -9.949 1.00 16.94 ? 2017 HOH A O 1 HETATM 8140 O O . HOH L 4 . ? -6.084 45.342 -2.705 1.00 23.55 ? 2018 HOH A O 1 HETATM 8141 O O . HOH L 4 . ? 11.684 18.544 -8.886 1.00 30.86 ? 2019 HOH A O 1 HETATM 8142 O O . HOH L 4 . ? 13.423 35.531 -6.701 1.00 20.73 ? 2020 HOH A O 1 HETATM 8143 O O . HOH L 4 . ? 25.749 40.200 -6.707 1.00 31.14 ? 2021 HOH A O 1 HETATM 8144 O O . HOH L 4 . ? -7.133 25.371 -1.274 1.00 40.52 ? 2022 HOH A O 1 HETATM 8145 O O . HOH L 4 . ? -19.124 23.011 -10.109 1.00 26.53 ? 2023 HOH A O 1 HETATM 8146 O O . HOH L 4 . ? -24.276 18.531 -3.749 1.00 37.26 ? 2024 HOH A O 1 HETATM 8147 O O . HOH L 4 . ? -21.392 18.964 -1.570 1.00 29.93 ? 2025 HOH A O 1 HETATM 8148 O O . HOH L 4 . ? -16.714 18.327 -12.884 1.00 26.72 ? 2026 HOH A O 1 HETATM 8149 O O . HOH L 4 . ? 13.929 29.000 -7.936 1.00 31.20 ? 2027 HOH A O 1 HETATM 8150 O O . HOH M 4 . ? 31.800 40.981 -30.006 1.00 29.58 ? 2001 HOH B O 1 HETATM 8151 O O . HOH M 4 . ? 17.527 47.458 -29.084 1.00 26.56 ? 2002 HOH B O 1 HETATM 8152 O O . HOH M 4 . ? 13.408 42.661 -32.912 1.00 19.18 ? 2003 HOH B O 1 HETATM 8153 O O . HOH M 4 . ? 29.133 40.539 -31.177 1.00 22.03 ? 2004 HOH B O 1 HETATM 8154 O O . HOH M 4 . ? 27.691 39.737 -28.975 1.00 23.29 ? 2005 HOH B O 1 HETATM 8155 O O . HOH M 4 . ? 10.575 32.863 -29.062 1.00 21.99 ? 2006 HOH B O 1 HETATM 8156 O O . HOH M 4 . ? 1.677 16.705 -35.381 1.00 40.77 ? 2007 HOH B O 1 HETATM 8157 O O . HOH M 4 . ? 21.940 45.935 -8.751 1.00 37.44 ? 2008 HOH B O 1 HETATM 8158 O O . HOH M 4 . ? 28.162 44.846 -9.667 1.00 25.19 ? 2009 HOH B O 1 HETATM 8159 O O . HOH M 4 . ? 11.886 42.742 -30.732 1.00 14.47 ? 2010 HOH B O 1 HETATM 8160 O O . HOH M 4 . ? 16.361 42.443 -37.485 1.00 17.71 ? 2011 HOH B O 1 HETATM 8161 O O . HOH M 4 . ? 14.323 40.685 -35.381 1.00 22.40 ? 2012 HOH B O 1 HETATM 8162 O O . HOH M 4 . ? 11.138 28.009 -34.426 1.00 18.19 ? 2013 HOH B O 1 HETATM 8163 O O . HOH M 4 . ? 11.630 25.308 -42.553 1.00 22.49 ? 2014 HOH B O 1 HETATM 8164 O O . HOH M 4 . ? 19.808 29.661 -40.469 1.00 27.20 ? 2015 HOH B O 1 HETATM 8165 O O . HOH M 4 . ? 0.400 32.155 -37.451 1.00 28.08 ? 2016 HOH B O 1 HETATM 8166 O O . HOH M 4 . ? 4.542 38.507 -21.081 1.00 7.54 ? 2017 HOH B O 1 HETATM 8167 O O . HOH M 4 . ? 27.359 37.641 -25.664 1.00 29.96 ? 2018 HOH B O 1 HETATM 8168 O O . HOH M 4 . ? 9.402 35.080 -27.280 1.00 18.47 ? 2019 HOH B O 1 HETATM 8169 O O . HOH M 4 . ? 17.100 7.970 -33.994 1.00 40.87 ? 2020 HOH B O 1 HETATM 8170 O O . HOH M 4 . ? 23.534 33.483 -40.546 1.00 27.00 ? 2021 HOH B O 1 HETATM 8171 O O . HOH M 4 . ? 24.853 18.210 -33.238 1.00 27.39 ? 2022 HOH B O 1 HETATM 8172 O O . HOH M 4 . ? 26.001 24.787 -47.734 1.00 26.51 ? 2023 HOH B O 1 HETATM 8173 O O . HOH M 4 . ? 11.206 36.149 -43.945 1.00 35.40 ? 2024 HOH B O 1 HETATM 8174 O O . HOH N 4 . ? 26.311 57.595 -42.753 1.00 31.08 ? 2001 HOH C O 1 HETATM 8175 O O . HOH N 4 . ? 5.734 49.597 -48.726 1.00 24.27 ? 2002 HOH C O 1 HETATM 8176 O O . HOH N 4 . ? 0.139 45.401 -46.729 1.00 20.40 ? 2003 HOH C O 1 HETATM 8177 O O . HOH N 4 . ? 8.663 39.530 -59.380 1.00 21.37 ? 2004 HOH C O 1 HETATM 8178 O O . HOH N 4 . ? 8.012 43.554 -59.180 1.00 20.01 ? 2005 HOH C O 1 HETATM 8179 O O . HOH N 4 . ? 25.864 45.260 -47.354 1.00 26.47 ? 2006 HOH C O 1 HETATM 8180 O O . HOH N 4 . ? 18.427 44.890 -41.073 1.00 22.64 ? 2007 HOH C O 1 HETATM 8181 O O . HOH N 4 . ? 5.644 42.273 -38.681 1.00 26.36 ? 2008 HOH C O 1 HETATM 8182 O O . HOH N 4 . ? -3.949 46.302 -50.956 1.00 15.12 ? 2009 HOH C O 1 HETATM 8183 O O . HOH N 4 . ? -2.305 43.908 -48.715 1.00 22.50 ? 2010 HOH C O 1 HETATM 8184 O O . HOH N 4 . ? -12.081 29.548 -51.667 1.00 21.63 ? 2011 HOH C O 1 HETATM 8185 O O . HOH N 4 . ? -8.497 21.540 -55.691 1.00 27.35 ? 2012 HOH C O 1 HETATM 8186 O O . HOH N 4 . ? 8.546 38.334 -35.415 1.00 15.07 ? 2013 HOH C O 1 HETATM 8187 O O . HOH N 4 . ? 2.324 36.607 -41.830 1.00 24.19 ? 2014 HOH C O 1 HETATM 8188 O O . HOH N 4 . ? 8.222 23.151 -63.249 1.00 31.32 ? 2015 HOH C O 1 HETATM 8189 O O . HOH N 4 . ? -13.679 38.114 -62.368 1.00 44.18 ? 2016 HOH C O 1 HETATM 8190 O O . HOH N 4 . ? -13.110 40.839 -49.546 1.00 22.46 ? 2017 HOH C O 1 HETATM 8191 O O . HOH O 4 . ? -7.468 51.974 -62.221 1.00 37.03 ? 2001 HOH D O 1 HETATM 8192 O O . HOH O 4 . ? -11.903 24.111 -53.144 1.00 26.15 ? 2002 HOH D O 1 HETATM 8193 O O . HOH O 4 . ? -16.913 53.860 -43.705 1.00 20.07 ? 2003 HOH D O 1 HETATM 8194 O O . HOH O 4 . ? -16.907 48.481 -38.701 1.00 20.73 ? 2004 HOH D O 1 HETATM 8195 O O . HOH O 4 . ? -27.380 51.678 -48.346 1.00 28.16 ? 2005 HOH D O 1 HETATM 8196 O O . HOH O 4 . ? -27.102 46.501 -51.470 1.00 20.96 ? 2006 HOH D O 1 HETATM 8197 O O . HOH O 4 . ? -26.259 49.585 -49.647 1.00 24.67 ? 2007 HOH D O 1 HETATM 8198 O O . HOH O 4 . ? -12.135 23.179 -50.230 1.00 22.10 ? 2008 HOH D O 1 HETATM 8199 O O . HOH O 4 . ? -18.376 51.226 -45.090 1.00 14.31 ? 2009 HOH D O 1 HETATM 8200 O O . HOH O 4 . ? -6.051 49.466 -53.690 1.00 23.70 ? 2010 HOH D O 1 HETATM 8201 O O . HOH O 4 . ? -19.975 47.442 -36.879 1.00 24.84 ? 2011 HOH D O 1 HETATM 8202 O O . HOH O 4 . ? -19.570 40.734 -41.580 1.00 24.48 ? 2012 HOH D O 1 HETATM 8203 O O . HOH O 4 . ? -19.597 40.614 -38.584 1.00 23.96 ? 2013 HOH D O 1 HETATM 8204 O O . HOH O 4 . ? -20.299 36.672 -37.145 1.00 27.40 ? 2014 HOH D O 1 HETATM 8205 O O . HOH O 4 . ? -21.247 34.015 -36.934 1.00 17.12 ? 2015 HOH D O 1 HETATM 8206 O O . HOH O 4 . ? -31.239 39.886 -37.788 1.00 24.84 ? 2016 HOH D O 1 HETATM 8207 O O . HOH O 4 . ? -13.699 34.646 -27.807 1.00 23.53 ? 2017 HOH D O 1 HETATM 8208 O O . HOH O 4 . ? -5.603 40.466 -43.133 1.00 17.95 ? 2018 HOH D O 1 HETATM 8209 O O . HOH O 4 . ? -22.546 58.242 -54.842 1.00 37.62 ? 2019 HOH D O 1 HETATM 8210 O O . HOH O 4 . ? -31.768 22.755 -40.373 1.00 38.55 ? 2020 HOH D O 1 HETATM 8211 O O . HOH O 4 . ? -22.860 40.764 -29.124 1.00 25.24 ? 2021 HOH D O 1 HETATM 8212 O O . HOH O 4 . ? -32.557 43.840 -38.888 1.00 28.34 ? 2022 HOH D O 1 HETATM 8213 O O . HOH O 4 . ? -8.355 15.607 -60.792 1.00 29.95 ? 2023 HOH D O 1 HETATM 8214 O O . HOH O 4 . ? -41.653 37.800 -42.976 1.00 18.45 ? 2024 HOH D O 1 HETATM 8215 O O . HOH O 4 . ? -34.682 29.325 -46.257 1.00 27.28 ? 2025 HOH D O 1 HETATM 8216 O O . HOH O 4 . ? -24.713 42.867 -27.832 1.00 18.50 ? 2026 HOH D O 1 HETATM 8217 O O . HOH P 4 . ? -28.311 60.458 -38.159 1.00 32.27 ? 2001 HOH E O 1 HETATM 8218 O O . HOH P 4 . ? -18.111 64.800 -36.434 1.00 36.07 ? 2002 HOH E O 1 HETATM 8219 O O . HOH P 4 . ? -18.703 54.248 -20.220 1.00 16.40 ? 2003 HOH E O 1 HETATM 8220 O O . HOH P 4 . ? -30.949 46.929 -14.260 1.00 18.76 ? 2004 HOH E O 1 HETATM 8221 O O . HOH P 4 . ? -27.746 26.548 -31.795 1.00 28.51 ? 2005 HOH E O 1 HETATM 8222 O O . HOH P 4 . ? -26.687 18.229 -29.000 1.00 28.09 ? 2006 HOH E O 1 HETATM 8223 O O . HOH P 4 . ? -21.762 39.953 -20.024 1.00 20.10 ? 2007 HOH E O 1 HETATM 8224 O O . HOH P 4 . ? -21.079 51.776 -19.616 1.00 16.51 ? 2008 HOH E O 1 HETATM 8225 O O . HOH P 4 . ? -25.193 53.066 -34.455 1.00 25.18 ? 2009 HOH E O 1 HETATM 8226 O O . HOH P 4 . ? -14.313 48.620 -13.337 1.00 19.94 ? 2010 HOH E O 1 HETATM 8227 O O . HOH P 4 . ? -14.233 46.915 -15.746 1.00 15.62 ? 2011 HOH E O 1 HETATM 8228 O O . HOH P 4 . ? -17.814 39.811 -18.810 1.00 23.23 ? 2012 HOH E O 1 HETATM 8229 O O . HOH P 4 . ? -15.295 36.277 -17.913 1.00 23.08 ? 2013 HOH E O 1 HETATM 8230 O O . HOH P 4 . ? -16.518 33.623 -17.598 1.00 24.49 ? 2014 HOH E O 1 HETATM 8231 O O . HOH P 4 . ? -19.604 37.545 -7.767 1.00 26.98 ? 2015 HOH E O 1 HETATM 8232 O O . HOH P 4 . ? -18.903 37.073 -34.844 1.00 19.50 ? 2016 HOH E O 1 HETATM 8233 O O . HOH P 4 . ? -16.133 42.167 -32.506 1.00 24.34 ? 2017 HOH E O 1 HETATM 8234 O O . HOH P 4 . ? -13.706 43.652 -27.941 1.00 25.70 ? 2018 HOH E O 1 HETATM 8235 O O . HOH P 4 . ? -17.720 40.237 -24.866 1.00 19.76 ? 2019 HOH E O 1 HETATM 8236 O O . HOH P 4 . ? -20.901 42.029 -5.890 1.00 24.44 ? 2020 HOH E O 1 HETATM 8237 O O . HOH P 4 . ? -29.478 11.040 -29.204 1.00 41.01 ? 2021 HOH E O 1 HETATM 8238 O O . HOH P 4 . ? -22.047 37.049 2.572 1.00 28.92 ? 2022 HOH E O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 MET 1 -18 ? ? ? A . n A 1 2 ARG 2 -17 ? ? ? A . n A 1 3 ARG 3 -16 ? ? ? A . n A 1 4 ASN 4 -15 ? ? ? A . n A 1 5 ILE 5 -14 ? ? ? A . n A 1 6 PHE 6 -13 ? ? ? A . n A 1 7 CYS 7 -12 ? ? ? A . n A 1 8 LEU 8 -11 ? ? ? A . n A 1 9 ALA 9 -10 ? ? ? A . n A 1 10 CYS 10 -9 ? ? ? A . n A 1 11 LEU 11 -8 ? ? ? A . n A 1 12 TRP 12 -7 ? ? ? A . n A 1 13 ILE 13 -6 ? ? ? A . n A 1 14 VAL 14 -5 ? ? ? A . n A 1 15 GLN 15 -4 ? ? ? A . n A 1 16 ALA 16 -3 ? ? ? A . n A 1 17 CYS 17 -2 ? ? ? A . n A 1 18 LEU 18 -1 ? ? ? A . n A 1 19 SER 19 0 ? ? ? A . n A 1 20 LEU 20 1 1 LEU LEU A . n A 1 21 ASP 21 2 2 ASP ASP A . n A 1 22 ARG 22 3 3 ARG ARG A . n A 1 23 ALA 23 4 4 ALA ALA A . n A 1 24 ASP 24 5 5 ASP ASP A . n A 1 25 ILE 25 6 6 ILE ILE A . n A 1 26 LEU 26 7 7 LEU LEU A . n A 1 27 TYR 27 8 8 TYR TYR A . n A 1 28 ASN 28 9 9 ASN ASN A . n A 1 29 ILE 29 10 10 ILE ILE A . n A 1 30 ARG 30 11 11 ARG ARG A . n A 1 31 GLN 31 12 12 GLN GLN A . n A 1 32 THR 32 13 13 THR THR A . n A 1 33 SER 33 14 14 SER SER A . n A 1 34 ARG 34 15 15 ARG ARG A . n A 1 35 PRO 35 16 16 PRO PRO A . n A 1 36 ASP 36 17 17 ASP ASP A . n A 1 37 VAL 37 18 18 VAL VAL A . n A 1 38 ILE 38 19 19 ILE ILE A . n A 1 39 PRO 39 20 20 PRO PRO A . n A 1 40 THR 40 21 21 THR THR A . n A 1 41 GLN 41 22 22 GLN GLN A . n A 1 42 ARG 42 23 23 ARG ARG A . n A 1 43 ASP 43 24 24 ASP ASP A . n A 1 44 ARG 44 25 25 ARG ARG A . n A 1 45 PRO 45 26 26 PRO PRO A . n A 1 46 VAL 46 27 27 VAL VAL A . n A 1 47 ALA 47 28 28 ALA ALA A . n A 1 48 VAL 48 29 29 VAL VAL A . n A 1 49 SER 49 30 30 SER SER A . n A 1 50 VAL 50 31 31 VAL VAL A . n A 1 51 SER 51 32 32 SER SER A . n A 1 52 LEU 52 33 33 LEU LEU A . n A 1 53 LYS 53 34 34 LYS LYS A . n A 1 54 PHE 54 35 35 PHE PHE A . n A 1 55 ILE 55 36 36 ILE ILE A . n A 1 56 ASN 56 37 37 ASN ASN A . n A 1 57 ILE 57 38 38 ILE ILE A . n A 1 58 LEU 58 39 39 LEU LEU A . n A 1 59 GLU 59 40 40 GLU GLU A . n A 1 60 VAL 60 41 41 VAL VAL A . n A 1 61 ASN 61 42 42 ASN ASN A . n A 1 62 GLU 62 43 43 GLU GLU A . n A 1 63 ILE 63 44 44 ILE ILE A . n A 1 64 THR 64 45 45 THR THR A . n A 1 65 ASN 65 46 46 ASN ASN A . n A 1 66 GLU 66 47 47 GLU GLU A . n A 1 67 VAL 67 48 48 VAL VAL A . n A 1 68 ASP 68 49 49 ASP ASP A . n A 1 69 VAL 69 50 50 VAL VAL A . n A 1 70 VAL 70 51 51 VAL VAL A . n A 1 71 PHE 71 52 52 PHE PHE A . n A 1 72 TRP 72 53 53 TRP TRP A . n A 1 73 GLN 73 54 54 GLN GLN A . n A 1 74 GLN 74 55 55 GLN GLN A . n A 1 75 THR 75 56 56 THR THR A . n A 1 76 THR 76 57 57 THR THR A . n A 1 77 TRP 77 58 58 TRP TRP A . n A 1 78 SER 78 59 59 SER SER A . n A 1 79 ASP 79 60 60 ASP ASP A . n A 1 80 ARG 80 61 61 ARG ARG A . n A 1 81 THR 81 62 62 THR THR A . n A 1 82 LEU 82 63 63 LEU LEU A . n A 1 83 ALA 83 64 64 ALA ALA A . n A 1 84 TRP 84 65 65 TRP TRP A . n A 1 85 ASN 85 66 66 ASN ASN A . n A 1 86 SER 86 67 67 SER SER A . n A 1 87 SER 87 68 68 SER SER A . n A 1 88 HIS 88 69 69 HIS HIS A . n A 1 89 SER 89 70 70 SER SER A . n A 1 90 PRO 90 71 71 PRO PRO A . n A 1 91 ASP 91 72 72 ASP ASP A . n A 1 92 GLN 92 73 73 GLN GLN A . n A 1 93 VAL 93 74 74 VAL VAL A . n A 1 94 SER 94 75 75 SER SER A . n A 1 95 VAL 95 76 76 VAL VAL A . n A 1 96 PRO 96 77 77 PRO PRO A . n A 1 97 ILE 97 78 78 ILE ILE A . n A 1 98 SER 98 79 79 SER SER A . n A 1 99 SER 99 80 80 SER SER A . n A 1 100 LEU 100 81 81 LEU LEU A . n A 1 101 TRP 101 82 82 TRP TRP A . n A 1 102 VAL 102 83 83 VAL VAL A . n A 1 103 PRO 103 84 84 PRO PRO A . n A 1 104 ASP 104 85 85 ASP ASP A . n A 1 105 LEU 105 86 86 LEU LEU A . n A 1 106 ALA 106 87 87 ALA ALA A . n A 1 107 ALA 107 88 88 ALA ALA A . n A 1 108 TYR 108 89 89 TYR TYR A . n A 1 109 ASN 109 90 90 ASN ASN A . n A 1 110 ALA 110 91 91 ALA ALA A . n A 1 111 ILE 111 92 92 ILE ILE A . n A 1 112 SER 112 93 93 SER SER A . n A 1 113 LYS 113 94 94 LYS LYS A . n A 1 114 PRO 114 95 95 PRO PRO A . n A 1 115 GLU 115 96 96 GLU GLU A . n A 1 116 VAL 116 97 97 VAL VAL A . n A 1 117 LEU 117 98 98 LEU LEU A . n A 1 118 THR 118 99 99 THR THR A . n A 1 119 PRO 119 100 100 PRO PRO A . n A 1 120 GLN 120 101 101 GLN GLN A . n A 1 121 LEU 121 102 102 LEU LEU A . n A 1 122 ALA 122 103 103 ALA ALA A . n A 1 123 HIS 123 104 104 HIS HIS A . n A 1 124 VAL 124 105 105 VAL VAL A . n A 1 125 VAL 125 106 106 VAL VAL A . n A 1 126 SER 126 107 107 SER SER A . n A 1 127 ASP 127 108 108 ASP ASP A . n A 1 128 GLY 128 109 109 GLY GLY A . n A 1 129 GLU 129 110 110 GLU GLU A . n A 1 130 VAL 130 111 111 VAL VAL A . n A 1 131 GLN 131 112 112 GLN GLN A . n A 1 132 TYR 132 113 113 TYR TYR A . n A 1 133 THR 133 114 114 THR THR A . n A 1 134 PRO 134 115 115 PRO PRO A . n A 1 135 SER 135 116 116 SER SER A . n A 1 136 ILE 136 117 117 ILE ILE A . n A 1 137 ARG 137 118 118 ARG ARG A . n A 1 138 GLN 138 119 119 GLN GLN A . n A 1 139 ARG 139 120 120 ARG ARG A . n A 1 140 PHE 140 121 121 PHE PHE A . n A 1 141 SER 141 122 122 SER SER A . n A 1 142 CYS 142 123 123 CYS CYS A . n A 1 143 ASP 143 124 124 ASP ASP A . n A 1 144 VAL 144 125 125 VAL VAL A . n A 1 145 SER 145 126 126 SER SER A . n A 1 146 GLY 146 127 127 GLY GLY A . n A 1 147 VAL 147 128 128 VAL VAL A . n A 1 148 ASP 148 129 129 ASP ASP A . n A 1 149 THR 149 130 130 THR THR A . n A 1 150 GLU 150 131 131 GLU GLU A . n A 1 151 SER 151 132 132 SER SER A . n A 1 152 GLY 152 133 133 GLY GLY A . n A 1 153 ALA 153 134 134 ALA ALA A . n A 1 154 THR 154 135 135 THR THR A . n A 1 155 CYS 155 136 136 CYS CYS A . n A 1 156 ARG 156 137 137 ARG ARG A . n A 1 157 ILE 157 138 138 ILE ILE A . n A 1 158 LYS 158 139 139 LYS LYS A . n A 1 159 ILE 159 140 140 ILE ILE A . n A 1 160 GLY 160 141 141 GLY GLY A . n A 1 161 SER 161 142 142 SER SER A . n A 1 162 TRP 162 143 143 TRP TRP A . n A 1 163 THR 163 144 144 THR THR A . n A 1 164 HIS 164 145 145 HIS HIS A . n A 1 165 HIS 165 146 146 HIS HIS A . n A 1 166 SER 166 147 147 SER SER A . n A 1 167 ARG 167 148 148 ARG ARG A . n A 1 168 GLU 168 149 149 GLU GLU A . n A 1 169 ILE 169 150 150 ILE ILE A . n A 1 170 SER 170 151 151 SER SER A . n A 1 171 VAL 171 152 152 VAL VAL A . n A 1 172 ASP 172 153 153 ASP ASP A . n A 1 173 PRO 173 154 154 PRO PRO A . n A 1 174 THR 174 155 155 THR THR A . n A 1 175 THR 175 156 156 THR THR A . n A 1 176 GLU 176 157 ? ? ? A . n A 1 177 ASN 177 158 ? ? ? A . n A 1 178 SER 178 159 ? ? ? A . n A 1 179 ASP 179 160 ? ? ? A . n A 1 180 ASP 180 161 161 ASP ASP A . n A 1 181 SER 181 162 162 SER SER A . n A 1 182 GLU 182 163 163 GLU GLU A . n A 1 183 TYR 183 164 164 TYR TYR A . n A 1 184 PHE 184 165 165 PHE PHE A . n A 1 185 SER 185 166 166 SER SER A . n A 1 186 GLN 186 167 167 GLN GLN A . n A 1 187 TYR 187 168 168 TYR TYR A . n A 1 188 SER 188 169 169 SER SER A . n A 1 189 ARG 189 170 170 ARG ARG A . n A 1 190 PHE 190 171 171 PHE PHE A . n A 1 191 GLU 191 172 172 GLU GLU A . n A 1 192 ILE 192 173 173 ILE ILE A . n A 1 193 LEU 193 174 174 LEU LEU A . n A 1 194 ASP 194 175 175 ASP ASP A . n A 1 195 VAL 195 176 176 VAL VAL A . n A 1 196 THR 196 177 177 THR THR A . n A 1 197 GLN 197 178 178 GLN GLN A . n A 1 198 LYS 198 179 179 LYS LYS A . n A 1 199 LYS 199 180 180 LYS LYS A . n A 1 200 ASN 200 181 181 ASN ASN A . n A 1 201 SER 201 182 182 SER SER A . n A 1 202 VAL 202 183 183 VAL VAL A . n A 1 203 THR 203 184 184 THR THR A . n A 1 204 TYR 204 185 185 TYR TYR A . n A 1 205 SER 205 186 186 SER SER A . n A 1 206 CYS 206 187 187 CYS CYS A . n A 1 207 CYS 207 188 188 CYS CYS A . n A 1 208 PRO 208 189 189 PRO PRO A . n A 1 209 GLU 209 190 190 GLU GLU A . n A 1 210 ALA 210 191 191 ALA ALA A . n A 1 211 TYR 211 192 192 TYR TYR A . n A 1 212 GLU 212 193 193 GLU GLU A . n A 1 213 ASP 213 194 194 ASP ASP A . n A 1 214 VAL 214 195 195 VAL VAL A . n A 1 215 GLU 215 196 196 GLU GLU A . n A 1 216 VAL 216 197 197 VAL VAL A . n A 1 217 SER 217 198 198 SER SER A . n A 1 218 LEU 218 199 199 LEU LEU A . n A 1 219 ASN 219 200 200 ASN ASN A . n A 1 220 PHE 220 201 201 PHE PHE A . n A 1 221 ARG 221 202 202 ARG ARG A . n A 1 222 LYS 222 203 203 LYS LYS A . n A 1 223 LYS 223 204 204 LYS LYS A . n A 1 224 GLY 224 205 ? ? ? A . n A 1 225 ARG 225 206 ? ? ? A . n A 1 226 SER 226 207 ? ? ? A . n A 1 227 GLU 227 208 ? ? ? A . n A 1 228 ILE 228 209 ? ? ? A . n A 1 229 LEU 229 210 ? ? ? A . n B 1 1 MET 1 -18 ? ? ? B . n B 1 2 ARG 2 -17 ? ? ? B . n B 1 3 ARG 3 -16 ? ? ? B . n B 1 4 ASN 4 -15 ? ? ? B . n B 1 5 ILE 5 -14 ? ? ? B . n B 1 6 PHE 6 -13 ? ? ? B . n B 1 7 CYS 7 -12 ? ? ? B . n B 1 8 LEU 8 -11 ? ? ? B . n B 1 9 ALA 9 -10 ? ? ? B . n B 1 10 CYS 10 -9 ? ? ? B . n B 1 11 LEU 11 -8 ? ? ? B . n B 1 12 TRP 12 -7 ? ? ? B . n B 1 13 ILE 13 -6 ? ? ? B . n B 1 14 VAL 14 -5 ? ? ? B . n B 1 15 GLN 15 -4 ? ? ? B . n B 1 16 ALA 16 -3 ? ? ? B . n B 1 17 CYS 17 -2 ? ? ? B . n B 1 18 LEU 18 -1 ? ? ? B . n B 1 19 SER 19 0 ? ? ? B . n B 1 20 LEU 20 1 1 LEU LEU B . n B 1 21 ASP 21 2 2 ASP ASP B . n B 1 22 ARG 22 3 3 ARG ARG B . n B 1 23 ALA 23 4 4 ALA ALA B . n B 1 24 ASP 24 5 5 ASP ASP B . n B 1 25 ILE 25 6 6 ILE ILE B . n B 1 26 LEU 26 7 7 LEU LEU B . n B 1 27 TYR 27 8 8 TYR TYR B . n B 1 28 ASN 28 9 9 ASN ASN B . n B 1 29 ILE 29 10 10 ILE ILE B . n B 1 30 ARG 30 11 11 ARG ARG B . n B 1 31 GLN 31 12 12 GLN GLN B . n B 1 32 THR 32 13 13 THR THR B . n B 1 33 SER 33 14 14 SER SER B . n B 1 34 ARG 34 15 15 ARG ARG B . n B 1 35 PRO 35 16 16 PRO PRO B . n B 1 36 ASP 36 17 17 ASP ASP B . n B 1 37 VAL 37 18 18 VAL VAL B . n B 1 38 ILE 38 19 19 ILE ILE B . n B 1 39 PRO 39 20 20 PRO PRO B . n B 1 40 THR 40 21 21 THR THR B . n B 1 41 GLN 41 22 22 GLN GLN B . n B 1 42 ARG 42 23 23 ARG ARG B . n B 1 43 ASP 43 24 24 ASP ASP B . n B 1 44 ARG 44 25 25 ARG ARG B . n B 1 45 PRO 45 26 26 PRO PRO B . n B 1 46 VAL 46 27 27 VAL VAL B . n B 1 47 ALA 47 28 28 ALA ALA B . n B 1 48 VAL 48 29 29 VAL VAL B . n B 1 49 SER 49 30 30 SER SER B . n B 1 50 VAL 50 31 31 VAL VAL B . n B 1 51 SER 51 32 32 SER SER B . n B 1 52 LEU 52 33 33 LEU LEU B . n B 1 53 LYS 53 34 34 LYS LYS B . n B 1 54 PHE 54 35 35 PHE PHE B . n B 1 55 ILE 55 36 36 ILE ILE B . n B 1 56 ASN 56 37 37 ASN ASN B . n B 1 57 ILE 57 38 38 ILE ILE B . n B 1 58 LEU 58 39 39 LEU LEU B . n B 1 59 GLU 59 40 40 GLU GLU B . n B 1 60 VAL 60 41 41 VAL VAL B . n B 1 61 ASN 61 42 42 ASN ASN B . n B 1 62 GLU 62 43 43 GLU GLU B . n B 1 63 ILE 63 44 44 ILE ILE B . n B 1 64 THR 64 45 45 THR THR B . n B 1 65 ASN 65 46 46 ASN ASN B . n B 1 66 GLU 66 47 47 GLU GLU B . n B 1 67 VAL 67 48 48 VAL VAL B . n B 1 68 ASP 68 49 49 ASP ASP B . n B 1 69 VAL 69 50 50 VAL VAL B . n B 1 70 VAL 70 51 51 VAL VAL B . n B 1 71 PHE 71 52 52 PHE PHE B . n B 1 72 TRP 72 53 53 TRP TRP B . n B 1 73 GLN 73 54 54 GLN GLN B . n B 1 74 GLN 74 55 55 GLN GLN B . n B 1 75 THR 75 56 56 THR THR B . n B 1 76 THR 76 57 57 THR THR B . n B 1 77 TRP 77 58 58 TRP TRP B . n B 1 78 SER 78 59 59 SER SER B . n B 1 79 ASP 79 60 60 ASP ASP B . n B 1 80 ARG 80 61 61 ARG ARG B . n B 1 81 THR 81 62 62 THR THR B . n B 1 82 LEU 82 63 63 LEU LEU B . n B 1 83 ALA 83 64 64 ALA ALA B . n B 1 84 TRP 84 65 65 TRP TRP B . n B 1 85 ASN 85 66 66 ASN ASN B . n B 1 86 SER 86 67 67 SER SER B . n B 1 87 SER 87 68 68 SER SER B . n B 1 88 HIS 88 69 69 HIS HIS B . n B 1 89 SER 89 70 70 SER SER B . n B 1 90 PRO 90 71 71 PRO PRO B . n B 1 91 ASP 91 72 72 ASP ASP B . n B 1 92 GLN 92 73 73 GLN GLN B . n B 1 93 VAL 93 74 74 VAL VAL B . n B 1 94 SER 94 75 75 SER SER B . n B 1 95 VAL 95 76 76 VAL VAL B . n B 1 96 PRO 96 77 77 PRO PRO B . n B 1 97 ILE 97 78 78 ILE ILE B . n B 1 98 SER 98 79 79 SER SER B . n B 1 99 SER 99 80 80 SER SER B . n B 1 100 LEU 100 81 81 LEU LEU B . n B 1 101 TRP 101 82 82 TRP TRP B . n B 1 102 VAL 102 83 83 VAL VAL B . n B 1 103 PRO 103 84 84 PRO PRO B . n B 1 104 ASP 104 85 85 ASP ASP B . n B 1 105 LEU 105 86 86 LEU LEU B . n B 1 106 ALA 106 87 87 ALA ALA B . n B 1 107 ALA 107 88 88 ALA ALA B . n B 1 108 TYR 108 89 89 TYR TYR B . n B 1 109 ASN 109 90 90 ASN ASN B . n B 1 110 ALA 110 91 91 ALA ALA B . n B 1 111 ILE 111 92 92 ILE ILE B . n B 1 112 SER 112 93 93 SER SER B . n B 1 113 LYS 113 94 94 LYS LYS B . n B 1 114 PRO 114 95 95 PRO PRO B . n B 1 115 GLU 115 96 96 GLU GLU B . n B 1 116 VAL 116 97 97 VAL VAL B . n B 1 117 LEU 117 98 98 LEU LEU B . n B 1 118 THR 118 99 99 THR THR B . n B 1 119 PRO 119 100 100 PRO PRO B . n B 1 120 GLN 120 101 101 GLN GLN B . n B 1 121 LEU 121 102 102 LEU LEU B . n B 1 122 ALA 122 103 103 ALA ALA B . n B 1 123 HIS 123 104 104 HIS HIS B . n B 1 124 VAL 124 105 105 VAL VAL B . n B 1 125 VAL 125 106 106 VAL VAL B . n B 1 126 SER 126 107 107 SER SER B . n B 1 127 ASP 127 108 108 ASP ASP B . n B 1 128 GLY 128 109 109 GLY GLY B . n B 1 129 GLU 129 110 110 GLU GLU B . n B 1 130 VAL 130 111 111 VAL VAL B . n B 1 131 GLN 131 112 112 GLN GLN B . n B 1 132 TYR 132 113 113 TYR TYR B . n B 1 133 THR 133 114 114 THR THR B . n B 1 134 PRO 134 115 115 PRO PRO B . n B 1 135 SER 135 116 116 SER SER B . n B 1 136 ILE 136 117 117 ILE ILE B . n B 1 137 ARG 137 118 118 ARG ARG B . n B 1 138 GLN 138 119 119 GLN GLN B . n B 1 139 ARG 139 120 120 ARG ARG B . n B 1 140 PHE 140 121 121 PHE PHE B . n B 1 141 SER 141 122 122 SER SER B . n B 1 142 CYS 142 123 123 CYS CYS B . n B 1 143 ASP 143 124 124 ASP ASP B . n B 1 144 VAL 144 125 125 VAL VAL B . n B 1 145 SER 145 126 126 SER SER B . n B 1 146 GLY 146 127 127 GLY GLY B . n B 1 147 VAL 147 128 128 VAL VAL B . n B 1 148 ASP 148 129 129 ASP ASP B . n B 1 149 THR 149 130 130 THR THR B . n B 1 150 GLU 150 131 131 GLU GLU B . n B 1 151 SER 151 132 132 SER SER B . n B 1 152 GLY 152 133 133 GLY GLY B . n B 1 153 ALA 153 134 134 ALA ALA B . n B 1 154 THR 154 135 135 THR THR B . n B 1 155 CYS 155 136 136 CYS CYS B . n B 1 156 ARG 156 137 137 ARG ARG B . n B 1 157 ILE 157 138 138 ILE ILE B . n B 1 158 LYS 158 139 139 LYS LYS B . n B 1 159 ILE 159 140 140 ILE ILE B . n B 1 160 GLY 160 141 141 GLY GLY B . n B 1 161 SER 161 142 142 SER SER B . n B 1 162 TRP 162 143 143 TRP TRP B . n B 1 163 THR 163 144 144 THR THR B . n B 1 164 HIS 164 145 145 HIS HIS B . n B 1 165 HIS 165 146 146 HIS HIS B . n B 1 166 SER 166 147 147 SER SER B . n B 1 167 ARG 167 148 148 ARG ARG B . n B 1 168 GLU 168 149 149 GLU GLU B . n B 1 169 ILE 169 150 150 ILE ILE B . n B 1 170 SER 170 151 151 SER SER B . n B 1 171 VAL 171 152 152 VAL VAL B . n B 1 172 ASP 172 153 153 ASP ASP B . n B 1 173 PRO 173 154 154 PRO PRO B . n B 1 174 THR 174 155 155 THR THR B . n B 1 175 THR 175 156 ? ? ? B . n B 1 176 GLU 176 157 ? ? ? B . n B 1 177 ASN 177 158 ? ? ? B . n B 1 178 SER 178 159 ? ? ? B . n B 1 179 ASP 179 160 ? ? ? B . n B 1 180 ASP 180 161 161 ASP ASP B . n B 1 181 SER 181 162 162 SER SER B . n B 1 182 GLU 182 163 163 GLU GLU B . n B 1 183 TYR 183 164 164 TYR TYR B . n B 1 184 PHE 184 165 165 PHE PHE B . n B 1 185 SER 185 166 166 SER SER B . n B 1 186 GLN 186 167 167 GLN GLN B . n B 1 187 TYR 187 168 168 TYR TYR B . n B 1 188 SER 188 169 169 SER SER B . n B 1 189 ARG 189 170 170 ARG ARG B . n B 1 190 PHE 190 171 171 PHE PHE B . n B 1 191 GLU 191 172 172 GLU GLU B . n B 1 192 ILE 192 173 173 ILE ILE B . n B 1 193 LEU 193 174 174 LEU LEU B . n B 1 194 ASP 194 175 175 ASP ASP B . n B 1 195 VAL 195 176 176 VAL VAL B . n B 1 196 THR 196 177 177 THR THR B . n B 1 197 GLN 197 178 178 GLN GLN B . n B 1 198 LYS 198 179 179 LYS LYS B . n B 1 199 LYS 199 180 180 LYS LYS B . n B 1 200 ASN 200 181 181 ASN ASN B . n B 1 201 SER 201 182 182 SER SER B . n B 1 202 VAL 202 183 183 VAL VAL B . n B 1 203 THR 203 184 184 THR THR B . n B 1 204 TYR 204 185 185 TYR TYR B . n B 1 205 SER 205 186 186 SER SER B . n B 1 206 CYS 206 187 187 CYS CYS B . n B 1 207 CYS 207 188 188 CYS CYS B . n B 1 208 PRO 208 189 189 PRO PRO B . n B 1 209 GLU 209 190 190 GLU GLU B . n B 1 210 ALA 210 191 191 ALA ALA B . n B 1 211 TYR 211 192 192 TYR TYR B . n B 1 212 GLU 212 193 193 GLU GLU B . n B 1 213 ASP 213 194 194 ASP ASP B . n B 1 214 VAL 214 195 195 VAL VAL B . n B 1 215 GLU 215 196 196 GLU GLU B . n B 1 216 VAL 216 197 197 VAL VAL B . n B 1 217 SER 217 198 198 SER SER B . n B 1 218 LEU 218 199 199 LEU LEU B . n B 1 219 ASN 219 200 200 ASN ASN B . n B 1 220 PHE 220 201 201 PHE PHE B . n B 1 221 ARG 221 202 202 ARG ARG B . n B 1 222 LYS 222 203 203 LYS LYS B . n B 1 223 LYS 223 204 204 LYS LYS B . n B 1 224 GLY 224 205 205 GLY GLY B . n B 1 225 ARG 225 206 ? ? ? B . n B 1 226 SER 226 207 ? ? ? B . n B 1 227 GLU 227 208 ? ? ? B . n B 1 228 ILE 228 209 ? ? ? B . n B 1 229 LEU 229 210 ? ? ? B . n C 1 1 MET 1 -18 ? ? ? C . n C 1 2 ARG 2 -17 ? ? ? C . n C 1 3 ARG 3 -16 ? ? ? C . n C 1 4 ASN 4 -15 ? ? ? C . n C 1 5 ILE 5 -14 ? ? ? C . n C 1 6 PHE 6 -13 ? ? ? C . n C 1 7 CYS 7 -12 ? ? ? C . n C 1 8 LEU 8 -11 ? ? ? C . n C 1 9 ALA 9 -10 ? ? ? C . n C 1 10 CYS 10 -9 ? ? ? C . n C 1 11 LEU 11 -8 ? ? ? C . n C 1 12 TRP 12 -7 ? ? ? C . n C 1 13 ILE 13 -6 ? ? ? C . n C 1 14 VAL 14 -5 ? ? ? C . n C 1 15 GLN 15 -4 ? ? ? C . n C 1 16 ALA 16 -3 ? ? ? C . n C 1 17 CYS 17 -2 ? ? ? C . n C 1 18 LEU 18 -1 ? ? ? C . n C 1 19 SER 19 0 ? ? ? C . n C 1 20 LEU 20 1 1 LEU LEU C . n C 1 21 ASP 21 2 2 ASP ASP C . n C 1 22 ARG 22 3 3 ARG ARG C . n C 1 23 ALA 23 4 4 ALA ALA C . n C 1 24 ASP 24 5 5 ASP ASP C . n C 1 25 ILE 25 6 6 ILE ILE C . n C 1 26 LEU 26 7 7 LEU LEU C . n C 1 27 TYR 27 8 8 TYR TYR C . n C 1 28 ASN 28 9 9 ASN ASN C . n C 1 29 ILE 29 10 10 ILE ILE C . n C 1 30 ARG 30 11 11 ARG ARG C . n C 1 31 GLN 31 12 12 GLN GLN C . n C 1 32 THR 32 13 13 THR THR C . n C 1 33 SER 33 14 14 SER SER C . n C 1 34 ARG 34 15 15 ARG ARG C . n C 1 35 PRO 35 16 16 PRO PRO C . n C 1 36 ASP 36 17 17 ASP ASP C . n C 1 37 VAL 37 18 18 VAL VAL C . n C 1 38 ILE 38 19 19 ILE ILE C . n C 1 39 PRO 39 20 20 PRO PRO C . n C 1 40 THR 40 21 21 THR THR C . n C 1 41 GLN 41 22 22 GLN GLN C . n C 1 42 ARG 42 23 23 ARG ARG C . n C 1 43 ASP 43 24 24 ASP ASP C . n C 1 44 ARG 44 25 25 ARG ARG C . n C 1 45 PRO 45 26 26 PRO PRO C . n C 1 46 VAL 46 27 27 VAL VAL C . n C 1 47 ALA 47 28 28 ALA ALA C . n C 1 48 VAL 48 29 29 VAL VAL C . n C 1 49 SER 49 30 30 SER SER C . n C 1 50 VAL 50 31 31 VAL VAL C . n C 1 51 SER 51 32 32 SER SER C . n C 1 52 LEU 52 33 33 LEU LEU C . n C 1 53 LYS 53 34 34 LYS LYS C . n C 1 54 PHE 54 35 35 PHE PHE C . n C 1 55 ILE 55 36 36 ILE ILE C . n C 1 56 ASN 56 37 37 ASN ASN C . n C 1 57 ILE 57 38 38 ILE ILE C . n C 1 58 LEU 58 39 39 LEU LEU C . n C 1 59 GLU 59 40 40 GLU GLU C . n C 1 60 VAL 60 41 41 VAL VAL C . n C 1 61 ASN 61 42 42 ASN ASN C . n C 1 62 GLU 62 43 43 GLU GLU C . n C 1 63 ILE 63 44 44 ILE ILE C . n C 1 64 THR 64 45 45 THR THR C . n C 1 65 ASN 65 46 46 ASN ASN C . n C 1 66 GLU 66 47 47 GLU GLU C . n C 1 67 VAL 67 48 48 VAL VAL C . n C 1 68 ASP 68 49 49 ASP ASP C . n C 1 69 VAL 69 50 50 VAL VAL C . n C 1 70 VAL 70 51 51 VAL VAL C . n C 1 71 PHE 71 52 52 PHE PHE C . n C 1 72 TRP 72 53 53 TRP TRP C . n C 1 73 GLN 73 54 54 GLN GLN C . n C 1 74 GLN 74 55 55 GLN GLN C . n C 1 75 THR 75 56 56 THR THR C . n C 1 76 THR 76 57 57 THR THR C . n C 1 77 TRP 77 58 58 TRP TRP C . n C 1 78 SER 78 59 59 SER SER C . n C 1 79 ASP 79 60 60 ASP ASP C . n C 1 80 ARG 80 61 61 ARG ARG C . n C 1 81 THR 81 62 62 THR THR C . n C 1 82 LEU 82 63 63 LEU LEU C . n C 1 83 ALA 83 64 64 ALA ALA C . n C 1 84 TRP 84 65 65 TRP TRP C . n C 1 85 ASN 85 66 66 ASN ASN C . n C 1 86 SER 86 67 67 SER SER C . n C 1 87 SER 87 68 68 SER SER C . n C 1 88 HIS 88 69 69 HIS HIS C . n C 1 89 SER 89 70 70 SER SER C . n C 1 90 PRO 90 71 71 PRO PRO C . n C 1 91 ASP 91 72 72 ASP ASP C . n C 1 92 GLN 92 73 73 GLN GLN C . n C 1 93 VAL 93 74 74 VAL VAL C . n C 1 94 SER 94 75 75 SER SER C . n C 1 95 VAL 95 76 76 VAL VAL C . n C 1 96 PRO 96 77 77 PRO PRO C . n C 1 97 ILE 97 78 78 ILE ILE C . n C 1 98 SER 98 79 79 SER SER C . n C 1 99 SER 99 80 80 SER SER C . n C 1 100 LEU 100 81 81 LEU LEU C . n C 1 101 TRP 101 82 82 TRP TRP C . n C 1 102 VAL 102 83 83 VAL VAL C . n C 1 103 PRO 103 84 84 PRO PRO C . n C 1 104 ASP 104 85 85 ASP ASP C . n C 1 105 LEU 105 86 86 LEU LEU C . n C 1 106 ALA 106 87 87 ALA ALA C . n C 1 107 ALA 107 88 88 ALA ALA C . n C 1 108 TYR 108 89 89 TYR TYR C . n C 1 109 ASN 109 90 90 ASN ASN C . n C 1 110 ALA 110 91 91 ALA ALA C . n C 1 111 ILE 111 92 92 ILE ILE C . n C 1 112 SER 112 93 93 SER SER C . n C 1 113 LYS 113 94 94 LYS LYS C . n C 1 114 PRO 114 95 95 PRO PRO C . n C 1 115 GLU 115 96 96 GLU GLU C . n C 1 116 VAL 116 97 97 VAL VAL C . n C 1 117 LEU 117 98 98 LEU LEU C . n C 1 118 THR 118 99 99 THR THR C . n C 1 119 PRO 119 100 100 PRO PRO C . n C 1 120 GLN 120 101 101 GLN GLN C . n C 1 121 LEU 121 102 102 LEU LEU C . n C 1 122 ALA 122 103 103 ALA ALA C . n C 1 123 HIS 123 104 104 HIS HIS C . n C 1 124 VAL 124 105 105 VAL VAL C . n C 1 125 VAL 125 106 106 VAL VAL C . n C 1 126 SER 126 107 107 SER SER C . n C 1 127 ASP 127 108 108 ASP ASP C . n C 1 128 GLY 128 109 109 GLY GLY C . n C 1 129 GLU 129 110 110 GLU GLU C . n C 1 130 VAL 130 111 111 VAL VAL C . n C 1 131 GLN 131 112 112 GLN GLN C . n C 1 132 TYR 132 113 113 TYR TYR C . n C 1 133 THR 133 114 114 THR THR C . n C 1 134 PRO 134 115 115 PRO PRO C . n C 1 135 SER 135 116 116 SER SER C . n C 1 136 ILE 136 117 117 ILE ILE C . n C 1 137 ARG 137 118 118 ARG ARG C . n C 1 138 GLN 138 119 119 GLN GLN C . n C 1 139 ARG 139 120 120 ARG ARG C . n C 1 140 PHE 140 121 121 PHE PHE C . n C 1 141 SER 141 122 122 SER SER C . n C 1 142 CYS 142 123 123 CYS CYS C . n C 1 143 ASP 143 124 124 ASP ASP C . n C 1 144 VAL 144 125 125 VAL VAL C . n C 1 145 SER 145 126 126 SER SER C . n C 1 146 GLY 146 127 127 GLY GLY C . n C 1 147 VAL 147 128 128 VAL VAL C . n C 1 148 ASP 148 129 129 ASP ASP C . n C 1 149 THR 149 130 130 THR THR C . n C 1 150 GLU 150 131 131 GLU GLU C . n C 1 151 SER 151 132 132 SER SER C . n C 1 152 GLY 152 133 133 GLY GLY C . n C 1 153 ALA 153 134 134 ALA ALA C . n C 1 154 THR 154 135 135 THR THR C . n C 1 155 CYS 155 136 136 CYS CYS C . n C 1 156 ARG 156 137 137 ARG ARG C . n C 1 157 ILE 157 138 138 ILE ILE C . n C 1 158 LYS 158 139 139 LYS LYS C . n C 1 159 ILE 159 140 140 ILE ILE C . n C 1 160 GLY 160 141 141 GLY GLY C . n C 1 161 SER 161 142 142 SER SER C . n C 1 162 TRP 162 143 143 TRP TRP C . n C 1 163 THR 163 144 144 THR THR C . n C 1 164 HIS 164 145 145 HIS HIS C . n C 1 165 HIS 165 146 146 HIS HIS C . n C 1 166 SER 166 147 147 SER SER C . n C 1 167 ARG 167 148 148 ARG ARG C . n C 1 168 GLU 168 149 149 GLU GLU C . n C 1 169 ILE 169 150 150 ILE ILE C . n C 1 170 SER 170 151 151 SER SER C . n C 1 171 VAL 171 152 152 VAL VAL C . n C 1 172 ASP 172 153 153 ASP ASP C . n C 1 173 PRO 173 154 154 PRO PRO C . n C 1 174 THR 174 155 155 THR THR C . n C 1 175 THR 175 156 ? ? ? C . n C 1 176 GLU 176 157 ? ? ? C . n C 1 177 ASN 177 158 ? ? ? C . n C 1 178 SER 178 159 ? ? ? C . n C 1 179 ASP 179 160 ? ? ? C . n C 1 180 ASP 180 161 ? ? ? C . n C 1 181 SER 181 162 162 SER SER C . n C 1 182 GLU 182 163 163 GLU GLU C . n C 1 183 TYR 183 164 164 TYR TYR C . n C 1 184 PHE 184 165 165 PHE PHE C . n C 1 185 SER 185 166 166 SER SER C . n C 1 186 GLN 186 167 167 GLN GLN C . n C 1 187 TYR 187 168 168 TYR TYR C . n C 1 188 SER 188 169 169 SER SER C . n C 1 189 ARG 189 170 170 ARG ARG C . n C 1 190 PHE 190 171 171 PHE PHE C . n C 1 191 GLU 191 172 172 GLU GLU C . n C 1 192 ILE 192 173 173 ILE ILE C . n C 1 193 LEU 193 174 174 LEU LEU C . n C 1 194 ASP 194 175 175 ASP ASP C . n C 1 195 VAL 195 176 176 VAL VAL C . n C 1 196 THR 196 177 177 THR THR C . n C 1 197 GLN 197 178 178 GLN GLN C . n C 1 198 LYS 198 179 179 LYS LYS C . n C 1 199 LYS 199 180 180 LYS LYS C . n C 1 200 ASN 200 181 181 ASN ASN C . n C 1 201 SER 201 182 182 SER SER C . n C 1 202 VAL 202 183 183 VAL VAL C . n C 1 203 THR 203 184 184 THR THR C . n C 1 204 TYR 204 185 185 TYR TYR C . n C 1 205 SER 205 186 186 SER SER C . n C 1 206 CYS 206 187 187 CYS CYS C . n C 1 207 CYS 207 188 188 CYS CYS C . n C 1 208 PRO 208 189 189 PRO PRO C . n C 1 209 GLU 209 190 190 GLU GLU C . n C 1 210 ALA 210 191 191 ALA ALA C . n C 1 211 TYR 211 192 192 TYR TYR C . n C 1 212 GLU 212 193 193 GLU GLU C . n C 1 213 ASP 213 194 194 ASP ASP C . n C 1 214 VAL 214 195 195 VAL VAL C . n C 1 215 GLU 215 196 196 GLU GLU C . n C 1 216 VAL 216 197 197 VAL VAL C . n C 1 217 SER 217 198 198 SER SER C . n C 1 218 LEU 218 199 199 LEU LEU C . n C 1 219 ASN 219 200 200 ASN ASN C . n C 1 220 PHE 220 201 201 PHE PHE C . n C 1 221 ARG 221 202 202 ARG ARG C . n C 1 222 LYS 222 203 203 LYS LYS C . n C 1 223 LYS 223 204 204 LYS LYS C . n C 1 224 GLY 224 205 205 GLY GLY C . n C 1 225 ARG 225 206 ? ? ? C . n C 1 226 SER 226 207 ? ? ? C . n C 1 227 GLU 227 208 ? ? ? C . n C 1 228 ILE 228 209 ? ? ? C . n C 1 229 LEU 229 210 ? ? ? C . n D 1 1 MET 1 -18 ? ? ? D . n D 1 2 ARG 2 -17 ? ? ? D . n D 1 3 ARG 3 -16 ? ? ? D . n D 1 4 ASN 4 -15 ? ? ? D . n D 1 5 ILE 5 -14 ? ? ? D . n D 1 6 PHE 6 -13 ? ? ? D . n D 1 7 CYS 7 -12 ? ? ? D . n D 1 8 LEU 8 -11 ? ? ? D . n D 1 9 ALA 9 -10 ? ? ? D . n D 1 10 CYS 10 -9 ? ? ? D . n D 1 11 LEU 11 -8 ? ? ? D . n D 1 12 TRP 12 -7 ? ? ? D . n D 1 13 ILE 13 -6 ? ? ? D . n D 1 14 VAL 14 -5 ? ? ? D . n D 1 15 GLN 15 -4 ? ? ? D . n D 1 16 ALA 16 -3 ? ? ? D . n D 1 17 CYS 17 -2 ? ? ? D . n D 1 18 LEU 18 -1 ? ? ? D . n D 1 19 SER 19 0 ? ? ? D . n D 1 20 LEU 20 1 1 LEU LEU D . n D 1 21 ASP 21 2 2 ASP ASP D . n D 1 22 ARG 22 3 3 ARG ARG D . n D 1 23 ALA 23 4 4 ALA ALA D . n D 1 24 ASP 24 5 5 ASP ASP D . n D 1 25 ILE 25 6 6 ILE ILE D . n D 1 26 LEU 26 7 7 LEU LEU D . n D 1 27 TYR 27 8 8 TYR TYR D . n D 1 28 ASN 28 9 9 ASN ASN D . n D 1 29 ILE 29 10 10 ILE ILE D . n D 1 30 ARG 30 11 11 ARG ARG D . n D 1 31 GLN 31 12 12 GLN GLN D . n D 1 32 THR 32 13 13 THR THR D . n D 1 33 SER 33 14 14 SER SER D . n D 1 34 ARG 34 15 15 ARG ARG D . n D 1 35 PRO 35 16 16 PRO PRO D . n D 1 36 ASP 36 17 17 ASP ASP D . n D 1 37 VAL 37 18 18 VAL VAL D . n D 1 38 ILE 38 19 19 ILE ILE D . n D 1 39 PRO 39 20 20 PRO PRO D . n D 1 40 THR 40 21 21 THR THR D . n D 1 41 GLN 41 22 22 GLN GLN D . n D 1 42 ARG 42 23 23 ARG ARG D . n D 1 43 ASP 43 24 24 ASP ASP D . n D 1 44 ARG 44 25 25 ARG ARG D . n D 1 45 PRO 45 26 26 PRO PRO D . n D 1 46 VAL 46 27 27 VAL VAL D . n D 1 47 ALA 47 28 28 ALA ALA D . n D 1 48 VAL 48 29 29 VAL VAL D . n D 1 49 SER 49 30 30 SER SER D . n D 1 50 VAL 50 31 31 VAL VAL D . n D 1 51 SER 51 32 32 SER SER D . n D 1 52 LEU 52 33 33 LEU LEU D . n D 1 53 LYS 53 34 34 LYS LYS D . n D 1 54 PHE 54 35 35 PHE PHE D . n D 1 55 ILE 55 36 36 ILE ILE D . n D 1 56 ASN 56 37 37 ASN ASN D . n D 1 57 ILE 57 38 38 ILE ILE D . n D 1 58 LEU 58 39 39 LEU LEU D . n D 1 59 GLU 59 40 40 GLU GLU D . n D 1 60 VAL 60 41 41 VAL VAL D . n D 1 61 ASN 61 42 42 ASN ASN D . n D 1 62 GLU 62 43 43 GLU GLU D . n D 1 63 ILE 63 44 44 ILE ILE D . n D 1 64 THR 64 45 45 THR THR D . n D 1 65 ASN 65 46 46 ASN ASN D . n D 1 66 GLU 66 47 47 GLU GLU D . n D 1 67 VAL 67 48 48 VAL VAL D . n D 1 68 ASP 68 49 49 ASP ASP D . n D 1 69 VAL 69 50 50 VAL VAL D . n D 1 70 VAL 70 51 51 VAL VAL D . n D 1 71 PHE 71 52 52 PHE PHE D . n D 1 72 TRP 72 53 53 TRP TRP D . n D 1 73 GLN 73 54 54 GLN GLN D . n D 1 74 GLN 74 55 55 GLN GLN D . n D 1 75 THR 75 56 56 THR THR D . n D 1 76 THR 76 57 57 THR THR D . n D 1 77 TRP 77 58 58 TRP TRP D . n D 1 78 SER 78 59 59 SER SER D . n D 1 79 ASP 79 60 60 ASP ASP D . n D 1 80 ARG 80 61 61 ARG ARG D . n D 1 81 THR 81 62 62 THR THR D . n D 1 82 LEU 82 63 63 LEU LEU D . n D 1 83 ALA 83 64 64 ALA ALA D . n D 1 84 TRP 84 65 65 TRP TRP D . n D 1 85 ASN 85 66 66 ASN ASN D . n D 1 86 SER 86 67 67 SER SER D . n D 1 87 SER 87 68 68 SER SER D . n D 1 88 HIS 88 69 69 HIS HIS D . n D 1 89 SER 89 70 70 SER SER D . n D 1 90 PRO 90 71 71 PRO PRO D . n D 1 91 ASP 91 72 72 ASP ASP D . n D 1 92 GLN 92 73 73 GLN GLN D . n D 1 93 VAL 93 74 74 VAL VAL D . n D 1 94 SER 94 75 75 SER SER D . n D 1 95 VAL 95 76 76 VAL VAL D . n D 1 96 PRO 96 77 77 PRO PRO D . n D 1 97 ILE 97 78 78 ILE ILE D . n D 1 98 SER 98 79 79 SER SER D . n D 1 99 SER 99 80 80 SER SER D . n D 1 100 LEU 100 81 81 LEU LEU D . n D 1 101 TRP 101 82 82 TRP TRP D . n D 1 102 VAL 102 83 83 VAL VAL D . n D 1 103 PRO 103 84 84 PRO PRO D . n D 1 104 ASP 104 85 85 ASP ASP D . n D 1 105 LEU 105 86 86 LEU LEU D . n D 1 106 ALA 106 87 87 ALA ALA D . n D 1 107 ALA 107 88 88 ALA ALA D . n D 1 108 TYR 108 89 89 TYR TYR D . n D 1 109 ASN 109 90 90 ASN ASN D . n D 1 110 ALA 110 91 91 ALA ALA D . n D 1 111 ILE 111 92 92 ILE ILE D . n D 1 112 SER 112 93 93 SER SER D . n D 1 113 LYS 113 94 94 LYS LYS D . n D 1 114 PRO 114 95 95 PRO PRO D . n D 1 115 GLU 115 96 96 GLU GLU D . n D 1 116 VAL 116 97 97 VAL VAL D . n D 1 117 LEU 117 98 98 LEU LEU D . n D 1 118 THR 118 99 99 THR THR D . n D 1 119 PRO 119 100 100 PRO PRO D . n D 1 120 GLN 120 101 101 GLN GLN D . n D 1 121 LEU 121 102 102 LEU LEU D . n D 1 122 ALA 122 103 103 ALA ALA D . n D 1 123 HIS 123 104 104 HIS HIS D . n D 1 124 VAL 124 105 105 VAL VAL D . n D 1 125 VAL 125 106 106 VAL VAL D . n D 1 126 SER 126 107 107 SER SER D . n D 1 127 ASP 127 108 108 ASP ASP D . n D 1 128 GLY 128 109 109 GLY GLY D . n D 1 129 GLU 129 110 110 GLU GLU D . n D 1 130 VAL 130 111 111 VAL VAL D . n D 1 131 GLN 131 112 112 GLN GLN D . n D 1 132 TYR 132 113 113 TYR TYR D . n D 1 133 THR 133 114 114 THR THR D . n D 1 134 PRO 134 115 115 PRO PRO D . n D 1 135 SER 135 116 116 SER SER D . n D 1 136 ILE 136 117 117 ILE ILE D . n D 1 137 ARG 137 118 118 ARG ARG D . n D 1 138 GLN 138 119 119 GLN GLN D . n D 1 139 ARG 139 120 120 ARG ARG D . n D 1 140 PHE 140 121 121 PHE PHE D . n D 1 141 SER 141 122 122 SER SER D . n D 1 142 CYS 142 123 123 CYS CYS D . n D 1 143 ASP 143 124 124 ASP ASP D . n D 1 144 VAL 144 125 125 VAL VAL D . n D 1 145 SER 145 126 126 SER SER D . n D 1 146 GLY 146 127 127 GLY GLY D . n D 1 147 VAL 147 128 128 VAL VAL D . n D 1 148 ASP 148 129 129 ASP ASP D . n D 1 149 THR 149 130 130 THR THR D . n D 1 150 GLU 150 131 131 GLU GLU D . n D 1 151 SER 151 132 132 SER SER D . n D 1 152 GLY 152 133 133 GLY GLY D . n D 1 153 ALA 153 134 134 ALA ALA D . n D 1 154 THR 154 135 135 THR THR D . n D 1 155 CYS 155 136 136 CYS CYS D . n D 1 156 ARG 156 137 137 ARG ARG D . n D 1 157 ILE 157 138 138 ILE ILE D . n D 1 158 LYS 158 139 139 LYS LYS D . n D 1 159 ILE 159 140 140 ILE ILE D . n D 1 160 GLY 160 141 141 GLY GLY D . n D 1 161 SER 161 142 142 SER SER D . n D 1 162 TRP 162 143 143 TRP TRP D . n D 1 163 THR 163 144 144 THR THR D . n D 1 164 HIS 164 145 145 HIS HIS D . n D 1 165 HIS 165 146 146 HIS HIS D . n D 1 166 SER 166 147 147 SER SER D . n D 1 167 ARG 167 148 148 ARG ARG D . n D 1 168 GLU 168 149 149 GLU GLU D . n D 1 169 ILE 169 150 150 ILE ILE D . n D 1 170 SER 170 151 151 SER SER D . n D 1 171 VAL 171 152 152 VAL VAL D . n D 1 172 ASP 172 153 153 ASP ASP D . n D 1 173 PRO 173 154 154 PRO PRO D . n D 1 174 THR 174 155 155 THR THR D . n D 1 175 THR 175 156 156 THR THR D . n D 1 176 GLU 176 157 157 GLU GLU D . n D 1 177 ASN 177 158 158 ASN ASN D . n D 1 178 SER 178 159 159 SER SER D . n D 1 179 ASP 179 160 ? ? ? D . n D 1 180 ASP 180 161 161 ASP ASP D . n D 1 181 SER 181 162 162 SER SER D . n D 1 182 GLU 182 163 163 GLU GLU D . n D 1 183 TYR 183 164 164 TYR TYR D . n D 1 184 PHE 184 165 165 PHE PHE D . n D 1 185 SER 185 166 166 SER SER D . n D 1 186 GLN 186 167 167 GLN GLN D . n D 1 187 TYR 187 168 168 TYR TYR D . n D 1 188 SER 188 169 169 SER SER D . n D 1 189 ARG 189 170 170 ARG ARG D . n D 1 190 PHE 190 171 171 PHE PHE D . n D 1 191 GLU 191 172 172 GLU GLU D . n D 1 192 ILE 192 173 173 ILE ILE D . n D 1 193 LEU 193 174 174 LEU LEU D . n D 1 194 ASP 194 175 175 ASP ASP D . n D 1 195 VAL 195 176 176 VAL VAL D . n D 1 196 THR 196 177 177 THR THR D . n D 1 197 GLN 197 178 178 GLN GLN D . n D 1 198 LYS 198 179 179 LYS LYS D . n D 1 199 LYS 199 180 180 LYS LYS D . n D 1 200 ASN 200 181 181 ASN ASN D . n D 1 201 SER 201 182 182 SER SER D . n D 1 202 VAL 202 183 183 VAL VAL D . n D 1 203 THR 203 184 184 THR THR D . n D 1 204 TYR 204 185 185 TYR TYR D . n D 1 205 SER 205 186 186 SER SER D . n D 1 206 CYS 206 187 187 CYS CYS D . n D 1 207 CYS 207 188 188 CYS CYS D . n D 1 208 PRO 208 189 189 PRO PRO D . n D 1 209 GLU 209 190 190 GLU GLU D . n D 1 210 ALA 210 191 191 ALA ALA D . n D 1 211 TYR 211 192 192 TYR TYR D . n D 1 212 GLU 212 193 193 GLU GLU D . n D 1 213 ASP 213 194 194 ASP ASP D . n D 1 214 VAL 214 195 195 VAL VAL D . n D 1 215 GLU 215 196 196 GLU GLU D . n D 1 216 VAL 216 197 197 VAL VAL D . n D 1 217 SER 217 198 198 SER SER D . n D 1 218 LEU 218 199 199 LEU LEU D . n D 1 219 ASN 219 200 200 ASN ASN D . n D 1 220 PHE 220 201 201 PHE PHE D . n D 1 221 ARG 221 202 202 ARG ARG D . n D 1 222 LYS 222 203 203 LYS LYS D . n D 1 223 LYS 223 204 204 LYS LYS D . n D 1 224 GLY 224 205 205 GLY GLY D . n D 1 225 ARG 225 206 ? ? ? D . n D 1 226 SER 226 207 ? ? ? D . n D 1 227 GLU 227 208 ? ? ? D . n D 1 228 ILE 228 209 ? ? ? D . n D 1 229 LEU 229 210 ? ? ? D . n E 1 1 MET 1 -18 ? ? ? E . n E 1 2 ARG 2 -17 ? ? ? E . n E 1 3 ARG 3 -16 ? ? ? E . n E 1 4 ASN 4 -15 ? ? ? E . n E 1 5 ILE 5 -14 ? ? ? E . n E 1 6 PHE 6 -13 ? ? ? E . n E 1 7 CYS 7 -12 ? ? ? E . n E 1 8 LEU 8 -11 ? ? ? E . n E 1 9 ALA 9 -10 ? ? ? E . n E 1 10 CYS 10 -9 ? ? ? E . n E 1 11 LEU 11 -8 ? ? ? E . n E 1 12 TRP 12 -7 ? ? ? E . n E 1 13 ILE 13 -6 ? ? ? E . n E 1 14 VAL 14 -5 ? ? ? E . n E 1 15 GLN 15 -4 ? ? ? E . n E 1 16 ALA 16 -3 ? ? ? E . n E 1 17 CYS 17 -2 ? ? ? E . n E 1 18 LEU 18 -1 ? ? ? E . n E 1 19 SER 19 0 ? ? ? E . n E 1 20 LEU 20 1 1 LEU LEU E . n E 1 21 ASP 21 2 2 ASP ASP E . n E 1 22 ARG 22 3 3 ARG ARG E . n E 1 23 ALA 23 4 4 ALA ALA E . n E 1 24 ASP 24 5 5 ASP ASP E . n E 1 25 ILE 25 6 6 ILE ILE E . n E 1 26 LEU 26 7 7 LEU LEU E . n E 1 27 TYR 27 8 8 TYR TYR E . n E 1 28 ASN 28 9 9 ASN ASN E . n E 1 29 ILE 29 10 10 ILE ILE E . n E 1 30 ARG 30 11 11 ARG ARG E . n E 1 31 GLN 31 12 12 GLN GLN E . n E 1 32 THR 32 13 13 THR THR E . n E 1 33 SER 33 14 14 SER SER E . n E 1 34 ARG 34 15 15 ARG ARG E . n E 1 35 PRO 35 16 16 PRO PRO E . n E 1 36 ASP 36 17 17 ASP ASP E . n E 1 37 VAL 37 18 18 VAL VAL E . n E 1 38 ILE 38 19 19 ILE ILE E . n E 1 39 PRO 39 20 20 PRO PRO E . n E 1 40 THR 40 21 21 THR THR E . n E 1 41 GLN 41 22 22 GLN GLN E . n E 1 42 ARG 42 23 23 ARG ARG E . n E 1 43 ASP 43 24 24 ASP ASP E . n E 1 44 ARG 44 25 25 ARG ARG E . n E 1 45 PRO 45 26 26 PRO PRO E . n E 1 46 VAL 46 27 27 VAL VAL E . n E 1 47 ALA 47 28 28 ALA ALA E . n E 1 48 VAL 48 29 29 VAL VAL E . n E 1 49 SER 49 30 30 SER SER E . n E 1 50 VAL 50 31 31 VAL VAL E . n E 1 51 SER 51 32 32 SER SER E . n E 1 52 LEU 52 33 33 LEU LEU E . n E 1 53 LYS 53 34 34 LYS LYS E . n E 1 54 PHE 54 35 35 PHE PHE E . n E 1 55 ILE 55 36 36 ILE ILE E . n E 1 56 ASN 56 37 37 ASN ASN E . n E 1 57 ILE 57 38 38 ILE ILE E . n E 1 58 LEU 58 39 39 LEU LEU E . n E 1 59 GLU 59 40 40 GLU GLU E . n E 1 60 VAL 60 41 41 VAL VAL E . n E 1 61 ASN 61 42 42 ASN ASN E . n E 1 62 GLU 62 43 43 GLU GLU E . n E 1 63 ILE 63 44 44 ILE ILE E . n E 1 64 THR 64 45 45 THR THR E . n E 1 65 ASN 65 46 46 ASN ASN E . n E 1 66 GLU 66 47 47 GLU GLU E . n E 1 67 VAL 67 48 48 VAL VAL E . n E 1 68 ASP 68 49 49 ASP ASP E . n E 1 69 VAL 69 50 50 VAL VAL E . n E 1 70 VAL 70 51 51 VAL VAL E . n E 1 71 PHE 71 52 52 PHE PHE E . n E 1 72 TRP 72 53 53 TRP TRP E . n E 1 73 GLN 73 54 54 GLN GLN E . n E 1 74 GLN 74 55 55 GLN GLN E . n E 1 75 THR 75 56 56 THR THR E . n E 1 76 THR 76 57 57 THR THR E . n E 1 77 TRP 77 58 58 TRP TRP E . n E 1 78 SER 78 59 59 SER SER E . n E 1 79 ASP 79 60 60 ASP ASP E . n E 1 80 ARG 80 61 61 ARG ARG E . n E 1 81 THR 81 62 62 THR THR E . n E 1 82 LEU 82 63 63 LEU LEU E . n E 1 83 ALA 83 64 64 ALA ALA E . n E 1 84 TRP 84 65 65 TRP TRP E . n E 1 85 ASN 85 66 66 ASN ASN E . n E 1 86 SER 86 67 67 SER SER E . n E 1 87 SER 87 68 68 SER SER E . n E 1 88 HIS 88 69 69 HIS HIS E . n E 1 89 SER 89 70 70 SER SER E . n E 1 90 PRO 90 71 71 PRO PRO E . n E 1 91 ASP 91 72 72 ASP ASP E . n E 1 92 GLN 92 73 73 GLN GLN E . n E 1 93 VAL 93 74 74 VAL VAL E . n E 1 94 SER 94 75 75 SER SER E . n E 1 95 VAL 95 76 76 VAL VAL E . n E 1 96 PRO 96 77 77 PRO PRO E . n E 1 97 ILE 97 78 78 ILE ILE E . n E 1 98 SER 98 79 79 SER SER E . n E 1 99 SER 99 80 80 SER SER E . n E 1 100 LEU 100 81 81 LEU LEU E . n E 1 101 TRP 101 82 82 TRP TRP E . n E 1 102 VAL 102 83 83 VAL VAL E . n E 1 103 PRO 103 84 84 PRO PRO E . n E 1 104 ASP 104 85 85 ASP ASP E . n E 1 105 LEU 105 86 86 LEU LEU E . n E 1 106 ALA 106 87 87 ALA ALA E . n E 1 107 ALA 107 88 88 ALA ALA E . n E 1 108 TYR 108 89 89 TYR TYR E . n E 1 109 ASN 109 90 90 ASN ASN E . n E 1 110 ALA 110 91 91 ALA ALA E . n E 1 111 ILE 111 92 92 ILE ILE E . n E 1 112 SER 112 93 93 SER SER E . n E 1 113 LYS 113 94 94 LYS LYS E . n E 1 114 PRO 114 95 95 PRO PRO E . n E 1 115 GLU 115 96 96 GLU GLU E . n E 1 116 VAL 116 97 97 VAL VAL E . n E 1 117 LEU 117 98 98 LEU LEU E . n E 1 118 THR 118 99 99 THR THR E . n E 1 119 PRO 119 100 100 PRO PRO E . n E 1 120 GLN 120 101 101 GLN GLN E . n E 1 121 LEU 121 102 102 LEU LEU E . n E 1 122 ALA 122 103 103 ALA ALA E . n E 1 123 HIS 123 104 104 HIS HIS E . n E 1 124 VAL 124 105 105 VAL VAL E . n E 1 125 VAL 125 106 106 VAL VAL E . n E 1 126 SER 126 107 107 SER SER E . n E 1 127 ASP 127 108 108 ASP ASP E . n E 1 128 GLY 128 109 109 GLY GLY E . n E 1 129 GLU 129 110 110 GLU GLU E . n E 1 130 VAL 130 111 111 VAL VAL E . n E 1 131 GLN 131 112 112 GLN GLN E . n E 1 132 TYR 132 113 113 TYR TYR E . n E 1 133 THR 133 114 114 THR THR E . n E 1 134 PRO 134 115 115 PRO PRO E . n E 1 135 SER 135 116 116 SER SER E . n E 1 136 ILE 136 117 117 ILE ILE E . n E 1 137 ARG 137 118 118 ARG ARG E . n E 1 138 GLN 138 119 119 GLN GLN E . n E 1 139 ARG 139 120 120 ARG ARG E . n E 1 140 PHE 140 121 121 PHE PHE E . n E 1 141 SER 141 122 122 SER SER E . n E 1 142 CYS 142 123 123 CYS CYS E . n E 1 143 ASP 143 124 124 ASP ASP E . n E 1 144 VAL 144 125 125 VAL VAL E . n E 1 145 SER 145 126 126 SER SER E . n E 1 146 GLY 146 127 127 GLY GLY E . n E 1 147 VAL 147 128 128 VAL VAL E . n E 1 148 ASP 148 129 129 ASP ASP E . n E 1 149 THR 149 130 130 THR THR E . n E 1 150 GLU 150 131 131 GLU GLU E . n E 1 151 SER 151 132 132 SER SER E . n E 1 152 GLY 152 133 133 GLY GLY E . n E 1 153 ALA 153 134 134 ALA ALA E . n E 1 154 THR 154 135 135 THR THR E . n E 1 155 CYS 155 136 136 CYS CYS E . n E 1 156 ARG 156 137 137 ARG ARG E . n E 1 157 ILE 157 138 138 ILE ILE E . n E 1 158 LYS 158 139 139 LYS LYS E . n E 1 159 ILE 159 140 140 ILE ILE E . n E 1 160 GLY 160 141 141 GLY GLY E . n E 1 161 SER 161 142 142 SER SER E . n E 1 162 TRP 162 143 143 TRP TRP E . n E 1 163 THR 163 144 144 THR THR E . n E 1 164 HIS 164 145 145 HIS HIS E . n E 1 165 HIS 165 146 146 HIS HIS E . n E 1 166 SER 166 147 147 SER SER E . n E 1 167 ARG 167 148 148 ARG ARG E . n E 1 168 GLU 168 149 149 GLU GLU E . n E 1 169 ILE 169 150 150 ILE ILE E . n E 1 170 SER 170 151 151 SER SER E . n E 1 171 VAL 171 152 152 VAL VAL E . n E 1 172 ASP 172 153 153 ASP ASP E . n E 1 173 PRO 173 154 154 PRO PRO E . n E 1 174 THR 174 155 155 THR THR E . n E 1 175 THR 175 156 ? ? ? E . n E 1 176 GLU 176 157 ? ? ? E . n E 1 177 ASN 177 158 ? ? ? E . n E 1 178 SER 178 159 159 SER SER E . n E 1 179 ASP 179 160 160 ASP ASP E . n E 1 180 ASP 180 161 161 ASP ASP E . n E 1 181 SER 181 162 162 SER SER E . n E 1 182 GLU 182 163 163 GLU GLU E . n E 1 183 TYR 183 164 164 TYR TYR E . n E 1 184 PHE 184 165 165 PHE PHE E . n E 1 185 SER 185 166 166 SER SER E . n E 1 186 GLN 186 167 167 GLN GLN E . n E 1 187 TYR 187 168 168 TYR TYR E . n E 1 188 SER 188 169 169 SER SER E . n E 1 189 ARG 189 170 170 ARG ARG E . n E 1 190 PHE 190 171 171 PHE PHE E . n E 1 191 GLU 191 172 172 GLU GLU E . n E 1 192 ILE 192 173 173 ILE ILE E . n E 1 193 LEU 193 174 174 LEU LEU E . n E 1 194 ASP 194 175 175 ASP ASP E . n E 1 195 VAL 195 176 176 VAL VAL E . n E 1 196 THR 196 177 177 THR THR E . n E 1 197 GLN 197 178 178 GLN GLN E . n E 1 198 LYS 198 179 179 LYS LYS E . n E 1 199 LYS 199 180 180 LYS LYS E . n E 1 200 ASN 200 181 181 ASN ASN E . n E 1 201 SER 201 182 182 SER SER E . n E 1 202 VAL 202 183 183 VAL VAL E . n E 1 203 THR 203 184 184 THR THR E . n E 1 204 TYR 204 185 185 TYR TYR E . n E 1 205 SER 205 186 186 SER SER E . n E 1 206 CYS 206 187 187 CYS CYS E . n E 1 207 CYS 207 188 188 CYS CYS E . n E 1 208 PRO 208 189 189 PRO PRO E . n E 1 209 GLU 209 190 190 GLU GLU E . n E 1 210 ALA 210 191 191 ALA ALA E . n E 1 211 TYR 211 192 192 TYR TYR E . n E 1 212 GLU 212 193 193 GLU GLU E . n E 1 213 ASP 213 194 194 ASP ASP E . n E 1 214 VAL 214 195 195 VAL VAL E . n E 1 215 GLU 215 196 196 GLU GLU E . n E 1 216 VAL 216 197 197 VAL VAL E . n E 1 217 SER 217 198 198 SER SER E . n E 1 218 LEU 218 199 199 LEU LEU E . n E 1 219 ASN 219 200 200 ASN ASN E . n E 1 220 PHE 220 201 201 PHE PHE E . n E 1 221 ARG 221 202 202 ARG ARG E . n E 1 222 LYS 222 203 203 LYS LYS E . n E 1 223 LYS 223 204 204 LYS LYS E . n E 1 224 GLY 224 205 ? ? ? E . n E 1 225 ARG 225 206 ? ? ? E . n E 1 226 SER 226 207 ? ? ? E . n E 1 227 GLU 227 208 ? ? ? E . n E 1 228 ILE 228 209 ? ? ? E . n E 1 229 LEU 229 210 ? ? ? E . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code F 2 09P 1 211 211 09P 09P A . G 2 09P 1 211 211 09P 09P B . H 2 09P 1 211 211 09P 09P C . I 2 09P 1 211 211 09P 09P D . J 3 NAG 1 1206 1206 NAG NAG D . K 2 09P 1 211 211 09P 09P E . L 4 HOH 1 2001 2001 HOH HOH A . L 4 HOH 2 2002 2002 HOH HOH A . L 4 HOH 3 2003 2003 HOH HOH A . L 4 HOH 4 2004 2004 HOH HOH A . L 4 HOH 5 2005 2005 HOH HOH A . L 4 HOH 6 2006 2006 HOH HOH A . L 4 HOH 7 2007 2007 HOH HOH A . L 4 HOH 8 2008 2008 HOH HOH A . L 4 HOH 9 2009 2009 HOH HOH A . L 4 HOH 10 2010 2010 HOH HOH A . L 4 HOH 11 2011 2011 HOH HOH A . L 4 HOH 12 2012 2012 HOH HOH A . L 4 HOH 13 2013 2013 HOH HOH A . L 4 HOH 14 2014 2014 HOH HOH A . L 4 HOH 15 2015 2015 HOH HOH A . L 4 HOH 16 2016 2016 HOH HOH A . L 4 HOH 17 2017 2017 HOH HOH A . L 4 HOH 18 2018 2018 HOH HOH A . L 4 HOH 19 2019 2019 HOH HOH A . L 4 HOH 20 2020 2020 HOH HOH A . L 4 HOH 21 2021 2021 HOH HOH A . L 4 HOH 22 2022 2022 HOH HOH A . L 4 HOH 23 2023 2023 HOH HOH A . L 4 HOH 24 2024 2024 HOH HOH A . L 4 HOH 25 2025 2025 HOH HOH A . L 4 HOH 26 2026 2026 HOH HOH A . L 4 HOH 27 2027 2027 HOH HOH A . M 4 HOH 1 2001 2001 HOH HOH B . M 4 HOH 2 2002 2002 HOH HOH B . M 4 HOH 3 2003 2003 HOH HOH B . M 4 HOH 4 2004 2004 HOH HOH B . M 4 HOH 5 2005 2005 HOH HOH B . M 4 HOH 6 2006 2006 HOH HOH B . M 4 HOH 7 2007 2007 HOH HOH B . M 4 HOH 8 2008 2008 HOH HOH B . M 4 HOH 9 2009 2009 HOH HOH B . M 4 HOH 10 2010 2010 HOH HOH B . M 4 HOH 11 2011 2011 HOH HOH B . M 4 HOH 12 2012 2012 HOH HOH B . M 4 HOH 13 2013 2013 HOH HOH B . M 4 HOH 14 2014 2014 HOH HOH B . M 4 HOH 15 2015 2015 HOH HOH B . M 4 HOH 16 2016 2016 HOH HOH B . M 4 HOH 17 2017 2017 HOH HOH B . M 4 HOH 18 2018 2018 HOH HOH B . M 4 HOH 19 2019 2019 HOH HOH B . M 4 HOH 20 2020 2020 HOH HOH B . M 4 HOH 21 2021 2021 HOH HOH B . M 4 HOH 22 2022 2022 HOH HOH B . M 4 HOH 23 2023 2023 HOH HOH B . M 4 HOH 24 2024 2024 HOH HOH B . N 4 HOH 1 2001 2001 HOH HOH C . N 4 HOH 2 2002 2002 HOH HOH C . N 4 HOH 3 2003 2003 HOH HOH C . N 4 HOH 4 2004 2004 HOH HOH C . N 4 HOH 5 2005 2005 HOH HOH C . N 4 HOH 6 2006 2006 HOH HOH C . N 4 HOH 7 2007 2007 HOH HOH C . N 4 HOH 8 2008 2008 HOH HOH C . N 4 HOH 9 2009 2009 HOH HOH C . N 4 HOH 10 2010 2010 HOH HOH C . N 4 HOH 11 2011 2011 HOH HOH C . N 4 HOH 12 2012 2012 HOH HOH C . N 4 HOH 13 2013 2013 HOH HOH C . N 4 HOH 14 2014 2014 HOH HOH C . N 4 HOH 15 2015 2015 HOH HOH C . N 4 HOH 16 2016 2016 HOH HOH C . N 4 HOH 17 2017 2017 HOH HOH C . O 4 HOH 1 2001 2001 HOH HOH D . O 4 HOH 2 2002 2002 HOH HOH D . O 4 HOH 3 2003 2003 HOH HOH D . O 4 HOH 4 2004 2004 HOH HOH D . O 4 HOH 5 2005 2005 HOH HOH D . O 4 HOH 6 2006 2006 HOH HOH D . O 4 HOH 7 2007 2007 HOH HOH D . O 4 HOH 8 2008 2008 HOH HOH D . O 4 HOH 9 2009 2009 HOH HOH D . O 4 HOH 10 2010 2010 HOH HOH D . O 4 HOH 11 2011 2011 HOH HOH D . O 4 HOH 12 2012 2012 HOH HOH D . O 4 HOH 13 2013 2013 HOH HOH D . O 4 HOH 14 2014 2014 HOH HOH D . O 4 HOH 15 2015 2015 HOH HOH D . O 4 HOH 16 2016 2016 HOH HOH D . O 4 HOH 17 2017 2017 HOH HOH D . O 4 HOH 18 2018 2018 HOH HOH D . O 4 HOH 19 2019 2019 HOH HOH D . O 4 HOH 20 2020 2020 HOH HOH D . O 4 HOH 21 2021 2021 HOH HOH D . O 4 HOH 22 2022 2022 HOH HOH D . O 4 HOH 23 2023 2023 HOH HOH D . O 4 HOH 24 2024 2024 HOH HOH D . O 4 HOH 25 2025 2025 HOH HOH D . O 4 HOH 26 2026 2026 HOH HOH D . P 4 HOH 1 2001 2001 HOH HOH E . P 4 HOH 2 2002 2002 HOH HOH E . P 4 HOH 3 2003 2003 HOH HOH E . P 4 HOH 4 2004 2004 HOH HOH E . P 4 HOH 5 2005 2005 HOH HOH E . P 4 HOH 6 2006 2006 HOH HOH E . P 4 HOH 7 2007 2007 HOH HOH E . P 4 HOH 8 2008 2008 HOH HOH E . P 4 HOH 9 2009 2009 HOH HOH E . P 4 HOH 10 2010 2010 HOH HOH E . P 4 HOH 11 2011 2011 HOH HOH E . P 4 HOH 12 2012 2012 HOH HOH E . P 4 HOH 13 2013 2013 HOH HOH E . P 4 HOH 14 2014 2014 HOH HOH E . P 4 HOH 15 2015 2015 HOH HOH E . P 4 HOH 16 2016 2016 HOH HOH E . P 4 HOH 17 2017 2017 HOH HOH E . P 4 HOH 18 2018 2018 HOH HOH E . P 4 HOH 19 2019 2019 HOH HOH E . P 4 HOH 20 2020 2020 HOH HOH E . P 4 HOH 21 2021 2021 HOH HOH E . P 4 HOH 22 2022 2022 HOH HOH E . # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id D _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 85 _pdbx_struct_mod_residue.auth_asym_id D _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 66 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details pentameric _pdbx_struct_assembly.oligomeric_count 5 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 13560 ? 1 MORE -37.9 ? 1 'SSA (A^2)' 42870 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2015-07-22 2 'Structure model' 1 1 2015-07-29 3 'Structure model' 1 2 2015-09-02 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Database references' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal PHENIX refinement '(PHENIX.REFINE)' ? 1 XDS 'data reduction' . ? 2 SCALA 'data scaling' . ? 3 PHASER phasing . ? 4 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OH E TYR 113 ? ? O E HOH 2019 ? ? 2.13 2 1 OG D SER 14 ? ? O D SER 80 ? ? 2.19 # _pdbx_validate_rmsd_bond.id 1 _pdbx_validate_rmsd_bond.PDB_model_num 1 _pdbx_validate_rmsd_bond.auth_atom_id_1 CA _pdbx_validate_rmsd_bond.auth_asym_id_1 E _pdbx_validate_rmsd_bond.auth_comp_id_1 ASP _pdbx_validate_rmsd_bond.auth_seq_id_1 17 _pdbx_validate_rmsd_bond.PDB_ins_code_1 ? _pdbx_validate_rmsd_bond.label_alt_id_1 A _pdbx_validate_rmsd_bond.auth_atom_id_2 C _pdbx_validate_rmsd_bond.auth_asym_id_2 E _pdbx_validate_rmsd_bond.auth_comp_id_2 ASP _pdbx_validate_rmsd_bond.auth_seq_id_2 17 _pdbx_validate_rmsd_bond.PDB_ins_code_2 ? _pdbx_validate_rmsd_bond.label_alt_id_2 ? _pdbx_validate_rmsd_bond.bond_value 1.706 _pdbx_validate_rmsd_bond.bond_target_value 1.525 _pdbx_validate_rmsd_bond.bond_deviation 0.181 _pdbx_validate_rmsd_bond.bond_standard_deviation 0.026 _pdbx_validate_rmsd_bond.linker_flag N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 C E PRO 16 ? ? N E ASP 17 ? ? CA E ASP 17 ? A 145.53 121.70 23.83 2.50 Y 2 1 C E PRO 16 ? ? N E ASP 17 ? ? CA E ASP 17 ? B 149.42 121.70 27.72 2.50 Y 3 1 CA E ASP 17 ? A C E ASP 17 ? ? O E ASP 17 ? ? 134.64 120.10 14.54 2.10 N 4 1 CA E ASP 17 ? B C E ASP 17 ? ? O E ASP 17 ? ? 137.48 120.10 17.38 2.10 N 5 1 CA E ASP 17 ? B C E ASP 17 ? ? N E VAL 18 ? ? 103.54 117.20 -13.66 2.20 Y # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ARG B 15 ? ? 59.90 71.26 2 1 ARG C 15 ? ? 58.64 71.54 3 1 SER D 162 ? ? -69.95 4.38 4 1 ARG E 15 ? ? 62.30 70.58 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A MET -18 ? A MET 1 2 1 Y 1 A ARG -17 ? A ARG 2 3 1 Y 1 A ARG -16 ? A ARG 3 4 1 Y 1 A ASN -15 ? A ASN 4 5 1 Y 1 A ILE -14 ? A ILE 5 6 1 Y 1 A PHE -13 ? A PHE 6 7 1 Y 1 A CYS -12 ? A CYS 7 8 1 Y 1 A LEU -11 ? A LEU 8 9 1 Y 1 A ALA -10 ? A ALA 9 10 1 Y 1 A CYS -9 ? A CYS 10 11 1 Y 1 A LEU -8 ? A LEU 11 12 1 Y 1 A TRP -7 ? A TRP 12 13 1 Y 1 A ILE -6 ? A ILE 13 14 1 Y 1 A VAL -5 ? A VAL 14 15 1 Y 1 A GLN -4 ? A GLN 15 16 1 Y 1 A ALA -3 ? A ALA 16 17 1 Y 1 A CYS -2 ? A CYS 17 18 1 Y 1 A LEU -1 ? A LEU 18 19 1 Y 1 A SER 0 ? A SER 19 20 1 Y 1 A GLU 157 ? A GLU 176 21 1 Y 1 A ASN 158 ? A ASN 177 22 1 Y 1 A SER 159 ? A SER 178 23 1 Y 1 A ASP 160 ? A ASP 179 24 1 Y 1 A GLY 205 ? A GLY 224 25 1 Y 1 A ARG 206 ? A ARG 225 26 1 Y 1 A SER 207 ? A SER 226 27 1 Y 1 A GLU 208 ? A GLU 227 28 1 Y 1 A ILE 209 ? A ILE 228 29 1 Y 1 A LEU 210 ? A LEU 229 30 1 Y 1 B MET -18 ? B MET 1 31 1 Y 1 B ARG -17 ? B ARG 2 32 1 Y 1 B ARG -16 ? B ARG 3 33 1 Y 1 B ASN -15 ? B ASN 4 34 1 Y 1 B ILE -14 ? B ILE 5 35 1 Y 1 B PHE -13 ? B PHE 6 36 1 Y 1 B CYS -12 ? B CYS 7 37 1 Y 1 B LEU -11 ? B LEU 8 38 1 Y 1 B ALA -10 ? B ALA 9 39 1 Y 1 B CYS -9 ? B CYS 10 40 1 Y 1 B LEU -8 ? B LEU 11 41 1 Y 1 B TRP -7 ? B TRP 12 42 1 Y 1 B ILE -6 ? B ILE 13 43 1 Y 1 B VAL -5 ? B VAL 14 44 1 Y 1 B GLN -4 ? B GLN 15 45 1 Y 1 B ALA -3 ? B ALA 16 46 1 Y 1 B CYS -2 ? B CYS 17 47 1 Y 1 B LEU -1 ? B LEU 18 48 1 Y 1 B SER 0 ? B SER 19 49 1 Y 1 B THR 156 ? B THR 175 50 1 Y 1 B GLU 157 ? B GLU 176 51 1 Y 1 B ASN 158 ? B ASN 177 52 1 Y 1 B SER 159 ? B SER 178 53 1 Y 1 B ASP 160 ? B ASP 179 54 1 Y 1 B ARG 206 ? B ARG 225 55 1 Y 1 B SER 207 ? B SER 226 56 1 Y 1 B GLU 208 ? B GLU 227 57 1 Y 1 B ILE 209 ? B ILE 228 58 1 Y 1 B LEU 210 ? B LEU 229 59 1 Y 1 C MET -18 ? C MET 1 60 1 Y 1 C ARG -17 ? C ARG 2 61 1 Y 1 C ARG -16 ? C ARG 3 62 1 Y 1 C ASN -15 ? C ASN 4 63 1 Y 1 C ILE -14 ? C ILE 5 64 1 Y 1 C PHE -13 ? C PHE 6 65 1 Y 1 C CYS -12 ? C CYS 7 66 1 Y 1 C LEU -11 ? C LEU 8 67 1 Y 1 C ALA -10 ? C ALA 9 68 1 Y 1 C CYS -9 ? C CYS 10 69 1 Y 1 C LEU -8 ? C LEU 11 70 1 Y 1 C TRP -7 ? C TRP 12 71 1 Y 1 C ILE -6 ? C ILE 13 72 1 Y 1 C VAL -5 ? C VAL 14 73 1 Y 1 C GLN -4 ? C GLN 15 74 1 Y 1 C ALA -3 ? C ALA 16 75 1 Y 1 C CYS -2 ? C CYS 17 76 1 Y 1 C LEU -1 ? C LEU 18 77 1 Y 1 C SER 0 ? C SER 19 78 1 Y 1 C THR 156 ? C THR 175 79 1 Y 1 C GLU 157 ? C GLU 176 80 1 Y 1 C ASN 158 ? C ASN 177 81 1 Y 1 C SER 159 ? C SER 178 82 1 Y 1 C ASP 160 ? C ASP 179 83 1 Y 1 C ASP 161 ? C ASP 180 84 1 Y 1 C ARG 206 ? C ARG 225 85 1 Y 1 C SER 207 ? C SER 226 86 1 Y 1 C GLU 208 ? C GLU 227 87 1 Y 1 C ILE 209 ? C ILE 228 88 1 Y 1 C LEU 210 ? C LEU 229 89 1 Y 1 D MET -18 ? D MET 1 90 1 Y 1 D ARG -17 ? D ARG 2 91 1 Y 1 D ARG -16 ? D ARG 3 92 1 Y 1 D ASN -15 ? D ASN 4 93 1 Y 1 D ILE -14 ? D ILE 5 94 1 Y 1 D PHE -13 ? D PHE 6 95 1 Y 1 D CYS -12 ? D CYS 7 96 1 Y 1 D LEU -11 ? D LEU 8 97 1 Y 1 D ALA -10 ? D ALA 9 98 1 Y 1 D CYS -9 ? D CYS 10 99 1 Y 1 D LEU -8 ? D LEU 11 100 1 Y 1 D TRP -7 ? D TRP 12 101 1 Y 1 D ILE -6 ? D ILE 13 102 1 Y 1 D VAL -5 ? D VAL 14 103 1 Y 1 D GLN -4 ? D GLN 15 104 1 Y 1 D ALA -3 ? D ALA 16 105 1 Y 1 D CYS -2 ? D CYS 17 106 1 Y 1 D LEU -1 ? D LEU 18 107 1 Y 1 D SER 0 ? D SER 19 108 1 Y 1 D ASP 160 ? D ASP 179 109 1 Y 1 D ARG 206 ? D ARG 225 110 1 Y 1 D SER 207 ? D SER 226 111 1 Y 1 D GLU 208 ? D GLU 227 112 1 Y 1 D ILE 209 ? D ILE 228 113 1 Y 1 D LEU 210 ? D LEU 229 114 1 Y 1 E MET -18 ? E MET 1 115 1 Y 1 E ARG -17 ? E ARG 2 116 1 Y 1 E ARG -16 ? E ARG 3 117 1 Y 1 E ASN -15 ? E ASN 4 118 1 Y 1 E ILE -14 ? E ILE 5 119 1 Y 1 E PHE -13 ? E PHE 6 120 1 Y 1 E CYS -12 ? E CYS 7 121 1 Y 1 E LEU -11 ? E LEU 8 122 1 Y 1 E ALA -10 ? E ALA 9 123 1 Y 1 E CYS -9 ? E CYS 10 124 1 Y 1 E LEU -8 ? E LEU 11 125 1 Y 1 E TRP -7 ? E TRP 12 126 1 Y 1 E ILE -6 ? E ILE 13 127 1 Y 1 E VAL -5 ? E VAL 14 128 1 Y 1 E GLN -4 ? E GLN 15 129 1 Y 1 E ALA -3 ? E ALA 16 130 1 Y 1 E CYS -2 ? E CYS 17 131 1 Y 1 E LEU -1 ? E LEU 18 132 1 Y 1 E SER 0 ? E SER 19 133 1 Y 1 E THR 156 ? E THR 175 134 1 Y 1 E GLU 157 ? E GLU 176 135 1 Y 1 E ASN 158 ? E ASN 177 136 1 Y 1 E GLY 205 ? E GLY 224 137 1 Y 1 E ARG 206 ? E ARG 225 138 1 Y 1 E SER 207 ? E SER 226 139 1 Y 1 E GLU 208 ? E GLU 227 140 1 Y 1 E ILE 209 ? E ILE 228 141 1 Y 1 E LEU 210 ? E LEU 229 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 '1-(5-ethoxypyridin-3-yl)-1,4-diazepane' 09P 3 N-ACETYL-D-GLUCOSAMINE NAG 4 water HOH #