data_4LXS # _entry.id 4LXS # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4LXS RCSB RCSB081219 WWPDB D_1000081219 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 3e07 'Spaetzle ligand' unspecified PDB 4LXR . unspecified # _pdbx_database_status.entry_id 4LXS _pdbx_database_status.status_code REL _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2013-07-30 _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Stelter, M.' 1 'Parthier, C.' 2 'Breithaupt, C.' 3 'Stubbs, M.T.' 4 # _citation.id primary _citation.title 'Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.' _citation.journal_abbrev Proc.Natl.Acad.Sci.USA _citation.journal_volume 111 _citation.page_first 6281 _citation.page_last 6286 _citation.year 2014 _citation.journal_id_ASTM PNASA6 _citation.country US _citation.journal_id_ISSN 0027-8424 _citation.journal_id_CSD 0040 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 24733933 _citation.pdbx_database_id_DOI 10.1073/pnas.1320678111 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Parthier, C.' 1 primary 'Stelter, M.' 2 primary 'Ursel, C.' 3 primary 'Fandrich, U.' 4 primary 'Lilie, H.' 5 primary 'Breithaupt, C.' 6 primary 'Stubbs, M.T.' 7 # _cell.entry_id 4LXS _cell.length_a 171.278 _cell.length_b 76.824 _cell.length_c 123.822 _cell.angle_alpha 90.00 _cell.angle_beta 126.29 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 4LXS _symmetry.space_group_name_H-M 'C 1 2 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 5 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Protein toll' 89632.398 1 ? ? 'UNP residues 28-802' ? 2 polymer man 'Protein spaetzle C-106' 13006.618 2 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 19 ? ? ? ? 4 non-polymer man BETA-D-MANNOSE 180.156 3 ? ? ? ? 5 non-polymer man ALPHA-D-MANNOSE 180.156 1 ? ? ? ? 6 non-polymer syn '4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID' 238.305 1 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;SFGRDACSEMSIDGLCQCAPIMSEYEIICPANAENPTFRLTIQPKDYVQIMCNLTDTTDYQQLPKKLRIGEVDRVQMRRC MLPGHTPIASILDYLGIVSPTTLIFESDNLGMNITRQHLDRLHGLKRFRFTTRRLTHIPANLLTDMRNLSHLELRANIEE MPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQLHNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAH LTNVTDINLSANLFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRLRAELQSLPGDLFEHSTQITNI SLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRNRLR TIDSRAFVSTNGLRHLHLDHNDIDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRNNSIIFVYNDWKNTMLQLRELDLSYN NISSLGYEDLAFLSQNRLHVNMTHNKIRRIALPEDVHLGEGYNNNLVHVDLNDNPLVCDCTILWFIQLVRGVHKPQYSRQ FKLRTDRLVCSQPNVLEGTPVRQIEPQTLICPLDFSDDPRERKCPRGCNCHVRTYDKALVINCHSGNLTHVPRLPNLHKN MQLMELHLENNTLLRLPSANTPGYESVTSLHLAGNNLTSIDVDQLPTNLTHLDISWNHLQMLNATVLGFLNRTMKWRSVK LSGNPWMCDCTAKPLLLFTQDNFERIGDRNEMMCVNAEMPTRMVELSTNDICPAETGHHHHHH ; ;SFGRDACSEMSIDGLCQCAPIMSEYEIICPANAENPTFRLTIQPKDYVQIMCNLTDTTDYQQLPKKLRIGEVDRVQMRRC MLPGHTPIASILDYLGIVSPTTLIFESDNLGMNITRQHLDRLHGLKRFRFTTRRLTHIPANLLTDMRNLSHLELRANIEE MPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQLHNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAH LTNVTDINLSANLFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRLRAELQSLPGDLFEHSTQITNI SLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRNRLR TIDSRAFVSTNGLRHLHLDHNDIDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRNNSIIFVYNDWKNTMLQLRELDLSYN NISSLGYEDLAFLSQNRLHVNMTHNKIRRIALPEDVHLGEGYNNNLVHVDLNDNPLVCDCTILWFIQLVRGVHKPQYSRQ FKLRTDRLVCSQPNVLEGTPVRQIEPQTLICPLDFSDDPRERKCPRGCNCHVRTYDKALVINCHSGNLTHVPRLPNLHKN MQLMELHLENNTLLRLPSANTPGYESVTSLHLAGNNLTSIDVDQLPTNLTHLDISWNHLQMLNATVLGFLNRTMKWRSVK LSGNPWMCDCTAKPLLLFTQDNFERIGDRNEMMCVNAEMPTRMVELSTNDICPAETGHHHHHH ; A ? 2 'polypeptide(L)' no no ;VGGSDERFLCRSIRKLVYPKKGLRADDTWQLIVNNDEYKQAIQIEECEGADQPCDFAANFPQSYNPICKQHYTQQTLASI KSDGELDVVQNSFKIPSCCKCALKTGLEHHHHHH ; ;VGGSDERFLCRSIRKLVYPKKGLRADDTWQLIVNNDEYKQAIQIEECEGADQPCDFAANFPQSYNPICKQHYTQQTLASI KSDGELDVVQNSFKIPSCCKCALKTGLEHHHHHH ; J,K ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 SER n 1 2 PHE n 1 3 GLY n 1 4 ARG n 1 5 ASP n 1 6 ALA n 1 7 CYS n 1 8 SER n 1 9 GLU n 1 10 MET n 1 11 SER n 1 12 ILE n 1 13 ASP n 1 14 GLY n 1 15 LEU n 1 16 CYS n 1 17 GLN n 1 18 CYS n 1 19 ALA n 1 20 PRO n 1 21 ILE n 1 22 MET n 1 23 SER n 1 24 GLU n 1 25 TYR n 1 26 GLU n 1 27 ILE n 1 28 ILE n 1 29 CYS n 1 30 PRO n 1 31 ALA n 1 32 ASN n 1 33 ALA n 1 34 GLU n 1 35 ASN n 1 36 PRO n 1 37 THR n 1 38 PHE n 1 39 ARG n 1 40 LEU n 1 41 THR n 1 42 ILE n 1 43 GLN n 1 44 PRO n 1 45 LYS n 1 46 ASP n 1 47 TYR n 1 48 VAL n 1 49 GLN n 1 50 ILE n 1 51 MET n 1 52 CYS n 1 53 ASN n 1 54 LEU n 1 55 THR n 1 56 ASP n 1 57 THR n 1 58 THR n 1 59 ASP n 1 60 TYR n 1 61 GLN n 1 62 GLN n 1 63 LEU n 1 64 PRO n 1 65 LYS n 1 66 LYS n 1 67 LEU n 1 68 ARG n 1 69 ILE n 1 70 GLY n 1 71 GLU n 1 72 VAL n 1 73 ASP n 1 74 ARG n 1 75 VAL n 1 76 GLN n 1 77 MET n 1 78 ARG n 1 79 ARG n 1 80 CYS n 1 81 MET n 1 82 LEU n 1 83 PRO n 1 84 GLY n 1 85 HIS n 1 86 THR n 1 87 PRO n 1 88 ILE n 1 89 ALA n 1 90 SER n 1 91 ILE n 1 92 LEU n 1 93 ASP n 1 94 TYR n 1 95 LEU n 1 96 GLY n 1 97 ILE n 1 98 VAL n 1 99 SER n 1 100 PRO n 1 101 THR n 1 102 THR n 1 103 LEU n 1 104 ILE n 1 105 PHE n 1 106 GLU n 1 107 SER n 1 108 ASP n 1 109 ASN n 1 110 LEU n 1 111 GLY n 1 112 MET n 1 113 ASN n 1 114 ILE n 1 115 THR n 1 116 ARG n 1 117 GLN n 1 118 HIS n 1 119 LEU n 1 120 ASP n 1 121 ARG n 1 122 LEU n 1 123 HIS n 1 124 GLY n 1 125 LEU n 1 126 LYS n 1 127 ARG n 1 128 PHE n 1 129 ARG n 1 130 PHE n 1 131 THR n 1 132 THR n 1 133 ARG n 1 134 ARG n 1 135 LEU n 1 136 THR n 1 137 HIS n 1 138 ILE n 1 139 PRO n 1 140 ALA n 1 141 ASN n 1 142 LEU n 1 143 LEU n 1 144 THR n 1 145 ASP n 1 146 MET n 1 147 ARG n 1 148 ASN n 1 149 LEU n 1 150 SER n 1 151 HIS n 1 152 LEU n 1 153 GLU n 1 154 LEU n 1 155 ARG n 1 156 ALA n 1 157 ASN n 1 158 ILE n 1 159 GLU n 1 160 GLU n 1 161 MET n 1 162 PRO n 1 163 SER n 1 164 HIS n 1 165 LEU n 1 166 PHE n 1 167 ASP n 1 168 ASP n 1 169 LEU n 1 170 GLU n 1 171 ASN n 1 172 LEU n 1 173 GLU n 1 174 SER n 1 175 ILE n 1 176 GLU n 1 177 PHE n 1 178 GLY n 1 179 SER n 1 180 ASN n 1 181 LYS n 1 182 LEU n 1 183 ARG n 1 184 GLN n 1 185 MET n 1 186 PRO n 1 187 ARG n 1 188 GLY n 1 189 ILE n 1 190 PHE n 1 191 GLY n 1 192 LYS n 1 193 MET n 1 194 PRO n 1 195 LYS n 1 196 LEU n 1 197 LYS n 1 198 GLN n 1 199 LEU n 1 200 ASN n 1 201 LEU n 1 202 TRP n 1 203 SER n 1 204 ASN n 1 205 GLN n 1 206 LEU n 1 207 HIS n 1 208 ASN n 1 209 LEU n 1 210 THR n 1 211 LYS n 1 212 HIS n 1 213 ASP n 1 214 PHE n 1 215 GLU n 1 216 GLY n 1 217 ALA n 1 218 THR n 1 219 SER n 1 220 VAL n 1 221 LEU n 1 222 GLY n 1 223 ILE n 1 224 ASP n 1 225 ILE n 1 226 HIS n 1 227 ASP n 1 228 ASN n 1 229 GLY n 1 230 ILE n 1 231 GLU n 1 232 GLN n 1 233 LEU n 1 234 PRO n 1 235 HIS n 1 236 ASP n 1 237 VAL n 1 238 PHE n 1 239 ALA n 1 240 HIS n 1 241 LEU n 1 242 THR n 1 243 ASN n 1 244 VAL n 1 245 THR n 1 246 ASP n 1 247 ILE n 1 248 ASN n 1 249 LEU n 1 250 SER n 1 251 ALA n 1 252 ASN n 1 253 LEU n 1 254 PHE n 1 255 ARG n 1 256 SER n 1 257 LEU n 1 258 PRO n 1 259 GLN n 1 260 GLY n 1 261 LEU n 1 262 PHE n 1 263 ASP n 1 264 HIS n 1 265 ASN n 1 266 LYS n 1 267 HIS n 1 268 LEU n 1 269 ASN n 1 270 GLU n 1 271 VAL n 1 272 ARG n 1 273 LEU n 1 274 MET n 1 275 ASN n 1 276 ASN n 1 277 ARG n 1 278 VAL n 1 279 PRO n 1 280 LEU n 1 281 ALA n 1 282 THR n 1 283 LEU n 1 284 PRO n 1 285 SER n 1 286 ARG n 1 287 LEU n 1 288 PHE n 1 289 ALA n 1 290 ASN n 1 291 GLN n 1 292 PRO n 1 293 GLU n 1 294 LEU n 1 295 GLN n 1 296 ILE n 1 297 LEU n 1 298 ARG n 1 299 LEU n 1 300 ARG n 1 301 ALA n 1 302 GLU n 1 303 LEU n 1 304 GLN n 1 305 SER n 1 306 LEU n 1 307 PRO n 1 308 GLY n 1 309 ASP n 1 310 LEU n 1 311 PHE n 1 312 GLU n 1 313 HIS n 1 314 SER n 1 315 THR n 1 316 GLN n 1 317 ILE n 1 318 THR n 1 319 ASN n 1 320 ILE n 1 321 SER n 1 322 LEU n 1 323 GLY n 1 324 ASP n 1 325 ASN n 1 326 LEU n 1 327 LEU n 1 328 LYS n 1 329 THR n 1 330 LEU n 1 331 PRO n 1 332 ALA n 1 333 THR n 1 334 LEU n 1 335 LEU n 1 336 GLU n 1 337 HIS n 1 338 GLN n 1 339 VAL n 1 340 ASN n 1 341 LEU n 1 342 LEU n 1 343 SER n 1 344 LEU n 1 345 ASP n 1 346 LEU n 1 347 SER n 1 348 ASN n 1 349 ASN n 1 350 ARG n 1 351 LEU n 1 352 THR n 1 353 HIS n 1 354 LEU n 1 355 PRO n 1 356 ASP n 1 357 SER n 1 358 LEU n 1 359 PHE n 1 360 ALA n 1 361 HIS n 1 362 THR n 1 363 THR n 1 364 ASN n 1 365 LEU n 1 366 THR n 1 367 ASP n 1 368 LEU n 1 369 ARG n 1 370 LEU n 1 371 GLU n 1 372 ASP n 1 373 ASN n 1 374 LEU n 1 375 LEU n 1 376 THR n 1 377 GLY n 1 378 ILE n 1 379 SER n 1 380 GLY n 1 381 ASP n 1 382 ILE n 1 383 PHE n 1 384 SER n 1 385 ASN n 1 386 LEU n 1 387 GLY n 1 388 ASN n 1 389 LEU n 1 390 VAL n 1 391 THR n 1 392 LEU n 1 393 VAL n 1 394 MET n 1 395 SER n 1 396 ARG n 1 397 ASN n 1 398 ARG n 1 399 LEU n 1 400 ARG n 1 401 THR n 1 402 ILE n 1 403 ASP n 1 404 SER n 1 405 ARG n 1 406 ALA n 1 407 PHE n 1 408 VAL n 1 409 SER n 1 410 THR n 1 411 ASN n 1 412 GLY n 1 413 LEU n 1 414 ARG n 1 415 HIS n 1 416 LEU n 1 417 HIS n 1 418 LEU n 1 419 ASP n 1 420 HIS n 1 421 ASN n 1 422 ASP n 1 423 ILE n 1 424 ASP n 1 425 LEU n 1 426 GLN n 1 427 GLN n 1 428 PRO n 1 429 LEU n 1 430 LEU n 1 431 ASP n 1 432 ILE n 1 433 MET n 1 434 LEU n 1 435 GLN n 1 436 THR n 1 437 GLN n 1 438 ILE n 1 439 ASN n 1 440 SER n 1 441 PRO n 1 442 PHE n 1 443 GLY n 1 444 TYR n 1 445 MET n 1 446 HIS n 1 447 GLY n 1 448 LEU n 1 449 LEU n 1 450 THR n 1 451 LEU n 1 452 ASN n 1 453 LEU n 1 454 ARG n 1 455 ASN n 1 456 ASN n 1 457 SER n 1 458 ILE n 1 459 ILE n 1 460 PHE n 1 461 VAL n 1 462 TYR n 1 463 ASN n 1 464 ASP n 1 465 TRP n 1 466 LYS n 1 467 ASN n 1 468 THR n 1 469 MET n 1 470 LEU n 1 471 GLN n 1 472 LEU n 1 473 ARG n 1 474 GLU n 1 475 LEU n 1 476 ASP n 1 477 LEU n 1 478 SER n 1 479 TYR n 1 480 ASN n 1 481 ASN n 1 482 ILE n 1 483 SER n 1 484 SER n 1 485 LEU n 1 486 GLY n 1 487 TYR n 1 488 GLU n 1 489 ASP n 1 490 LEU n 1 491 ALA n 1 492 PHE n 1 493 LEU n 1 494 SER n 1 495 GLN n 1 496 ASN n 1 497 ARG n 1 498 LEU n 1 499 HIS n 1 500 VAL n 1 501 ASN n 1 502 MET n 1 503 THR n 1 504 HIS n 1 505 ASN n 1 506 LYS n 1 507 ILE n 1 508 ARG n 1 509 ARG n 1 510 ILE n 1 511 ALA n 1 512 LEU n 1 513 PRO n 1 514 GLU n 1 515 ASP n 1 516 VAL n 1 517 HIS n 1 518 LEU n 1 519 GLY n 1 520 GLU n 1 521 GLY n 1 522 TYR n 1 523 ASN n 1 524 ASN n 1 525 ASN n 1 526 LEU n 1 527 VAL n 1 528 HIS n 1 529 VAL n 1 530 ASP n 1 531 LEU n 1 532 ASN n 1 533 ASP n 1 534 ASN n 1 535 PRO n 1 536 LEU n 1 537 VAL n 1 538 CYS n 1 539 ASP n 1 540 CYS n 1 541 THR n 1 542 ILE n 1 543 LEU n 1 544 TRP n 1 545 PHE n 1 546 ILE n 1 547 GLN n 1 548 LEU n 1 549 VAL n 1 550 ARG n 1 551 GLY n 1 552 VAL n 1 553 HIS n 1 554 LYS n 1 555 PRO n 1 556 GLN n 1 557 TYR n 1 558 SER n 1 559 ARG n 1 560 GLN n 1 561 PHE n 1 562 LYS n 1 563 LEU n 1 564 ARG n 1 565 THR n 1 566 ASP n 1 567 ARG n 1 568 LEU n 1 569 VAL n 1 570 CYS n 1 571 SER n 1 572 GLN n 1 573 PRO n 1 574 ASN n 1 575 VAL n 1 576 LEU n 1 577 GLU n 1 578 GLY n 1 579 THR n 1 580 PRO n 1 581 VAL n 1 582 ARG n 1 583 GLN n 1 584 ILE n 1 585 GLU n 1 586 PRO n 1 587 GLN n 1 588 THR n 1 589 LEU n 1 590 ILE n 1 591 CYS n 1 592 PRO n 1 593 LEU n 1 594 ASP n 1 595 PHE n 1 596 SER n 1 597 ASP n 1 598 ASP n 1 599 PRO n 1 600 ARG n 1 601 GLU n 1 602 ARG n 1 603 LYS n 1 604 CYS n 1 605 PRO n 1 606 ARG n 1 607 GLY n 1 608 CYS n 1 609 ASN n 1 610 CYS n 1 611 HIS n 1 612 VAL n 1 613 ARG n 1 614 THR n 1 615 TYR n 1 616 ASP n 1 617 LYS n 1 618 ALA n 1 619 LEU n 1 620 VAL n 1 621 ILE n 1 622 ASN n 1 623 CYS n 1 624 HIS n 1 625 SER n 1 626 GLY n 1 627 ASN n 1 628 LEU n 1 629 THR n 1 630 HIS n 1 631 VAL n 1 632 PRO n 1 633 ARG n 1 634 LEU n 1 635 PRO n 1 636 ASN n 1 637 LEU n 1 638 HIS n 1 639 LYS n 1 640 ASN n 1 641 MET n 1 642 GLN n 1 643 LEU n 1 644 MET n 1 645 GLU n 1 646 LEU n 1 647 HIS n 1 648 LEU n 1 649 GLU n 1 650 ASN n 1 651 ASN n 1 652 THR n 1 653 LEU n 1 654 LEU n 1 655 ARG n 1 656 LEU n 1 657 PRO n 1 658 SER n 1 659 ALA n 1 660 ASN n 1 661 THR n 1 662 PRO n 1 663 GLY n 1 664 TYR n 1 665 GLU n 1 666 SER n 1 667 VAL n 1 668 THR n 1 669 SER n 1 670 LEU n 1 671 HIS n 1 672 LEU n 1 673 ALA n 1 674 GLY n 1 675 ASN n 1 676 ASN n 1 677 LEU n 1 678 THR n 1 679 SER n 1 680 ILE n 1 681 ASP n 1 682 VAL n 1 683 ASP n 1 684 GLN n 1 685 LEU n 1 686 PRO n 1 687 THR n 1 688 ASN n 1 689 LEU n 1 690 THR n 1 691 HIS n 1 692 LEU n 1 693 ASP n 1 694 ILE n 1 695 SER n 1 696 TRP n 1 697 ASN n 1 698 HIS n 1 699 LEU n 1 700 GLN n 1 701 MET n 1 702 LEU n 1 703 ASN n 1 704 ALA n 1 705 THR n 1 706 VAL n 1 707 LEU n 1 708 GLY n 1 709 PHE n 1 710 LEU n 1 711 ASN n 1 712 ARG n 1 713 THR n 1 714 MET n 1 715 LYS n 1 716 TRP n 1 717 ARG n 1 718 SER n 1 719 VAL n 1 720 LYS n 1 721 LEU n 1 722 SER n 1 723 GLY n 1 724 ASN n 1 725 PRO n 1 726 TRP n 1 727 MET n 1 728 CYS n 1 729 ASP n 1 730 CYS n 1 731 THR n 1 732 ALA n 1 733 LYS n 1 734 PRO n 1 735 LEU n 1 736 LEU n 1 737 LEU n 1 738 PHE n 1 739 THR n 1 740 GLN n 1 741 ASP n 1 742 ASN n 1 743 PHE n 1 744 GLU n 1 745 ARG n 1 746 ILE n 1 747 GLY n 1 748 ASP n 1 749 ARG n 1 750 ASN n 1 751 GLU n 1 752 MET n 1 753 MET n 1 754 CYS n 1 755 VAL n 1 756 ASN n 1 757 ALA n 1 758 GLU n 1 759 MET n 1 760 PRO n 1 761 THR n 1 762 ARG n 1 763 MET n 1 764 VAL n 1 765 GLU n 1 766 LEU n 1 767 SER n 1 768 THR n 1 769 ASN n 1 770 ASP n 1 771 ILE n 1 772 CYS n 1 773 PRO n 1 774 ALA n 1 775 GLU n 1 776 THR n 1 777 GLY n 1 778 HIS n 1 779 HIS n 1 780 HIS n 1 781 HIS n 1 782 HIS n 1 783 HIS n 2 1 VAL n 2 2 GLY n 2 3 GLY n 2 4 SER n 2 5 ASP n 2 6 GLU n 2 7 ARG n 2 8 PHE n 2 9 LEU n 2 10 CYS n 2 11 ARG n 2 12 SER n 2 13 ILE n 2 14 ARG n 2 15 LYS n 2 16 LEU n 2 17 VAL n 2 18 TYR n 2 19 PRO n 2 20 LYS n 2 21 LYS n 2 22 GLY n 2 23 LEU n 2 24 ARG n 2 25 ALA n 2 26 ASP n 2 27 ASP n 2 28 THR n 2 29 TRP n 2 30 GLN n 2 31 LEU n 2 32 ILE n 2 33 VAL n 2 34 ASN n 2 35 ASN n 2 36 ASP n 2 37 GLU n 2 38 TYR n 2 39 LYS n 2 40 GLN n 2 41 ALA n 2 42 ILE n 2 43 GLN n 2 44 ILE n 2 45 GLU n 2 46 GLU n 2 47 CYS n 2 48 GLU n 2 49 GLY n 2 50 ALA n 2 51 ASP n 2 52 GLN n 2 53 PRO n 2 54 CYS n 2 55 ASP n 2 56 PHE n 2 57 ALA n 2 58 ALA n 2 59 ASN n 2 60 PHE n 2 61 PRO n 2 62 GLN n 2 63 SER n 2 64 TYR n 2 65 ASN n 2 66 PRO n 2 67 ILE n 2 68 CYS n 2 69 LYS n 2 70 GLN n 2 71 HIS n 2 72 TYR n 2 73 THR n 2 74 GLN n 2 75 GLN n 2 76 THR n 2 77 LEU n 2 78 ALA n 2 79 SER n 2 80 ILE n 2 81 LYS n 2 82 SER n 2 83 ASP n 2 84 GLY n 2 85 GLU n 2 86 LEU n 2 87 ASP n 2 88 VAL n 2 89 VAL n 2 90 GLN n 2 91 ASN n 2 92 SER n 2 93 PHE n 2 94 LYS n 2 95 ILE n 2 96 PRO n 2 97 SER n 2 98 CYS n 2 99 CYS n 2 100 LYS n 2 101 CYS n 2 102 ALA n 2 103 LEU n 2 104 LYS n 2 105 THR n 2 106 GLY n 2 107 LEU n 2 108 GLU n 2 109 HIS n 2 110 HIS n 2 111 HIS n 2 112 HIS n 2 113 HIS n 2 114 HIS n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample ? ? ? 'Fruit fly' ? 'Tl, CG5490' ? ? ? ? ? ? 'Drosophila melanogaster' 7227 ? ? ? ? ? ? ? ? 'Drosophila melanogaster' 7227 ? ? ? ? ? ? 'Schneider 2' ? ? ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample ? ? ? 'Fruit fly' ? 'spz, CG6134' ? ? ? ? ? ? 'Drosophila melanogaster' 7227 ? ? ? ? ? ? ? ? 'Escherichia coli' 562 ? ? ? ? ? ? 'Rosetta (DE3)' ? ? ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin _struct_ref.pdbx_db_isoform 1 UNP TOLL_DROME P08953 1 ;SFGRDACSEMSIDGLCQCAPIMSEYEIICPANAENPTFRLTIQPKDYVQIMCNLTDTTDYQQLPKKLRIGEVDRVQMRRC MLPGHTPIASILDYLGIVSPTTLIFESDNLGMNITRQHLDRLHGLKRFRFTTRRLTHIPANLLTDMRNLSHLELRANIEE MPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQLHNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAH LTNVTDINLSANLFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRLRAELQSLPGDLFEHSTQITNI SLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRNRLR TIDSRAFVSTNGLRHLHLDHNDIDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRNNSIIFVYNDWKNTMLQLRELDLSYN NISSLGYEDLAFLSQNRLHVNMTHNKIRRIALPEDVHLGEGYNNNLVHVDLNDNPLVCDCTILWFIQLVRGVHKPQYSRQ FKLRTDRLVCSQPNVLEGTPVRQIEPQTLICPLDFSDDPRERKCPRGCNCHVRTYDKALVINCHSGNLTHVPRLPNLHKN MQLMELHLENNTLLRLPSANTPGYESVTSLHLAGNNLTSIDVDQLPTNLTHLDISWNHLQMLNATVLGFLNRTMKWRSVK LSGNPWMCDCTAKPLLLFTQDNFERIGDRNEMMCVNAEMPTRMVELSTNDICPAE ; 28 ? 2 UNP SPZ_DROME P48607 2 ;VGGSDERFLCRSIRKLVYPKKGLRADDTWQLIVNNDEYKQAIQIEECEGADQPCDFAANFPQSYNPICKQHYTQQTLASI KSDGELDVVQNSFKIPSCCKCALKTG ; 221 ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4LXS A 1 ? 775 ? P08953 28 ? 802 ? 28 802 2 2 4LXS J 1 ? 106 ? P48607 221 ? 326 ? 1 106 3 2 4LXS K 1 ? 106 ? P48607 221 ? 326 ? 1 106 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4LXS THR A 776 ? UNP P08953 ? ? 'EXPRESSION TAG' 803 1 1 4LXS GLY A 777 ? UNP P08953 ? ? 'EXPRESSION TAG' 804 2 1 4LXS HIS A 778 ? UNP P08953 ? ? 'EXPRESSION TAG' 805 3 1 4LXS HIS A 779 ? UNP P08953 ? ? 'EXPRESSION TAG' 806 4 1 4LXS HIS A 780 ? UNP P08953 ? ? 'EXPRESSION TAG' 807 5 1 4LXS HIS A 781 ? UNP P08953 ? ? 'EXPRESSION TAG' 808 6 1 4LXS HIS A 782 ? UNP P08953 ? ? 'EXPRESSION TAG' 809 7 1 4LXS HIS A 783 ? UNP P08953 ? ? 'EXPRESSION TAG' 810 8 2 4LXS LEU J 107 ? UNP P48607 ? ? 'EXPRESSION TAG' 107 9 2 4LXS GLU J 108 ? UNP P48607 ? ? 'EXPRESSION TAG' 108 10 2 4LXS HIS J 109 ? UNP P48607 ? ? 'EXPRESSION TAG' 109 11 2 4LXS HIS J 110 ? UNP P48607 ? ? 'EXPRESSION TAG' 110 12 2 4LXS HIS J 111 ? UNP P48607 ? ? 'EXPRESSION TAG' 111 13 2 4LXS HIS J 112 ? UNP P48607 ? ? 'EXPRESSION TAG' 112 14 2 4LXS HIS J 113 ? UNP P48607 ? ? 'EXPRESSION TAG' 113 15 2 4LXS HIS J 114 ? UNP P48607 ? ? 'EXPRESSION TAG' 114 16 3 4LXS LEU K 107 ? UNP P48607 ? ? 'EXPRESSION TAG' 107 17 3 4LXS GLU K 108 ? UNP P48607 ? ? 'EXPRESSION TAG' 108 18 3 4LXS HIS K 109 ? UNP P48607 ? ? 'EXPRESSION TAG' 109 19 3 4LXS HIS K 110 ? UNP P48607 ? ? 'EXPRESSION TAG' 110 20 3 4LXS HIS K 111 ? UNP P48607 ? ? 'EXPRESSION TAG' 111 21 3 4LXS HIS K 112 ? UNP P48607 ? ? 'EXPRESSION TAG' 112 22 3 4LXS HIS K 113 ? UNP P48607 ? ? 'EXPRESSION TAG' 113 23 3 4LXS HIS K 114 ? UNP P48607 ? ? 'EXPRESSION TAG' 114 24 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 EPE non-polymer . '4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID' HEPES 'C8 H18 N2 O4 S' 238.305 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 4LXS _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.84 _exptl_crystal.density_percent_sol 56.67 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 287 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7.5 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '100 mM HEPES, 5% (v/v) propan-2-ol, 10% PEG 4000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 287K' # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'MARMOSAIC 225 mm CCD' _diffrn_detector.pdbx_collection_date 2012-03-08 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'BESSY BL 14.2' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9184 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'BESSY BEAMLINE 14.2' _diffrn_source.pdbx_synchrotron_site BESSY _diffrn_source.pdbx_synchrotron_beamline 14.2 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.9184 # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 4LXS _reflns.observed_criterion_sigma_I -3 _reflns.observed_criterion_sigma_F 2.0 _reflns.d_resolution_low 34 _reflns.d_resolution_high 3.3 _reflns.number_obs 18492 _reflns.number_all 19867 _reflns.percent_possible_obs 93.1 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy ? _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 3.3 _reflns_shell.d_res_low 3.4 _reflns_shell.percent_possible_all 80.3 _reflns_shell.Rmerge_I_obs 0.498 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 1.8 _reflns_shell.pdbx_redundancy ? _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 4LXS _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 18480 _refine.ls_number_reflns_all 18492 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.36 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 33.948 _refine.ls_d_res_high 3.300 _refine.ls_percent_reflns_obs 93.59 _refine.ls_R_factor_obs 0.2094 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.2066 _refine.ls_R_factor_R_free 0.2636 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.01 _refine.ls_number_reflns_R_free 925 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min 1.000 _refine.occupancy_max 1.000 _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 34.8766 _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_ls_cross_valid_method ? _refine.details ? _refine.pdbx_starting_model 'PDB ENTRY 4LXR' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.49 _refine.pdbx_overall_phase_error 31.30 _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6986 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 325 _refine_hist.number_atoms_solvent 0 _refine_hist.number_atoms_total 7311 _refine_hist.d_res_high 3.300 _refine_hist.d_res_low 33.948 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function f_bond_d 0.005 ? ? 7480 'X-RAY DIFFRACTION' ? f_angle_d 0.947 ? ? 10140 'X-RAY DIFFRACTION' ? f_dihedral_angle_d 21.299 ? ? 2848 'X-RAY DIFFRACTION' ? f_chiral_restr 0.060 ? ? 1213 'X-RAY DIFFRACTION' ? f_plane_restr 0.004 ? ? 1277 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_all _refine_ls_shell.R_factor_all _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.number_reflns_obs 'X-RAY DIFFRACTION' . 3.30 3.4739 2205 0.3038 82.00 0.3906 . . 117 . . . . 'X-RAY DIFFRACTION' . 3.4739 3.6913 2329 0.2474 89.00 0.3282 . . 123 . . . . 'X-RAY DIFFRACTION' . 3.6913 3.9759 2508 0.2064 94.00 0.2428 . . 131 . . . . 'X-RAY DIFFRACTION' . 3.9759 4.3752 2588 0.1796 97.00 0.2467 . . 136 . . . . 'X-RAY DIFFRACTION' . 4.3752 5.0066 2620 0.1659 98.00 0.2339 . . 138 . . . . 'X-RAY DIFFRACTION' . 5.0066 6.3012 2646 0.2235 98.00 0.2512 . . 139 . . . . 'X-RAY DIFFRACTION' . 6.3012 33.9494 2659 0.2014 97.00 0.2569 . . 141 . . . . # _struct.entry_id 4LXS _struct.title 'Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)' _struct.pdbx_descriptor 'Protein toll, Protein spaetzle C-106' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 4LXS _struct_keywords.text ;TLR, LEUCINE-RICH REPEAT, IMMUNE SYSTEM, CYTOKINE RECEPTOR, EMBRYONIC DEVELOPMENT, INNATE IMMUNITY, RECEPTOR-LIGAND COMPLEX, IMMUNE SYSTEM-CYTOKINE complex ; _struct_keywords.pdbx_keywords 'IMMUNE SYSTEM/CYTOKINE' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 3 ? E N N 3 ? F N N 4 ? G N N 4 ? H N N 5 ? I N N 3 ? J N N 3 ? K N N 3 ? L N N 3 ? M N N 3 ? N N N 3 ? O N N 4 ? P N N 3 ? Q N N 3 ? R N N 3 ? S N N 3 ? T N N 3 ? U N N 3 ? V N N 3 ? W N N 3 ? X N N 3 ? Y N N 3 ? Z N N 3 ? AA N N 6 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 GLY A 3 ? GLU A 9 ? GLY A 30 GLU A 36 1 ? 7 HELX_P HELX_P2 2 ASP A 56 ? LEU A 63 ? ASP A 83 LEU A 90 5 ? 8 HELX_P HELX_P3 3 PRO A 87 ? LEU A 95 ? PRO A 114 LEU A 122 1 ? 9 HELX_P HELX_P4 4 THR A 115 ? ASP A 120 ? THR A 142 ASP A 147 5 ? 6 HELX_P HELX_P5 5 PRO A 162 ? PHE A 166 ? PRO A 189 PHE A 193 5 ? 5 HELX_P HELX_P6 6 THR A 210 ? GLU A 215 ? THR A 237 GLU A 242 5 ? 6 HELX_P HELX_P7 7 PRO A 307 ? GLU A 312 ? PRO A 334 GLU A 339 5 ? 6 HELX_P HELX_P8 8 PRO A 331 ? GLU A 336 ? PRO A 358 GLU A 363 5 ? 6 HELX_P HELX_P9 9 SER A 404 ? VAL A 408 ? SER A 431 VAL A 435 5 ? 5 HELX_P HELX_P10 10 PRO A 428 ? LEU A 434 ? PRO A 455 LEU A 461 1 ? 7 HELX_P HELX_P11 11 ASN A 463 ? THR A 468 ? ASN A 490 THR A 495 1 ? 6 HELX_P HELX_P12 12 ASP A 539 ? THR A 541 ? ASP A 566 THR A 568 5 ? 3 HELX_P HELX_P13 13 ILE A 542 ? ARG A 550 ? ILE A 569 ARG A 577 1 ? 9 HELX_P HELX_P14 14 GLN A 556 ? ARG A 559 ? GLN A 583 ARG A 586 5 ? 4 HELX_P HELX_P15 15 GLY A 663 ? VAL A 667 ? GLY A 690 VAL A 694 5 ? 5 HELX_P HELX_P16 16 ASN A 703 ? LEU A 710 ? ASN A 730 LEU A 737 1 ? 8 HELX_P HELX_P17 17 ALA A 732 ? ASN A 742 ? ALA A 759 ASN A 769 1 ? 11 HELX_P HELX_P18 18 ASP A 748 ? MET A 752 ? ASP A 775 MET A 779 5 ? 5 HELX_P HELX_P19 19 ARG A 762 ? LEU A 766 ? ARG A 789 LEU A 793 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 7 SG ? ? ? 1_555 A CYS 18 SG ? ? A CYS 34 A CYS 45 1_555 ? ? ? ? ? ? ? 2.025 ? disulf2 disulf ? ? A CYS 16 SG ? ? ? 1_555 A CYS 29 SG ? ? A CYS 43 A CYS 56 1_555 ? ? ? ? ? ? ? 2.026 ? disulf3 disulf ? ? A CYS 52 SG ? ? ? 1_555 A CYS 80 SG ? ? A CYS 79 A CYS 107 1_555 ? ? ? ? ? ? ? 2.036 ? disulf4 disulf ? ? A CYS 538 SG ? ? ? 1_555 A CYS 570 SG ? ? A CYS 565 A CYS 597 1_555 ? ? ? ? ? ? ? 2.035 ? disulf5 disulf ? ? A CYS 540 SG ? ? ? 1_555 A CYS 591 SG ? ? A CYS 567 A CYS 618 1_555 ? ? ? ? ? ? ? 2.030 ? disulf6 disulf ? ? A CYS 604 SG ? ? ? 1_555 A CYS 610 SG ? ? A CYS 631 A CYS 637 1_555 ? ? ? ? ? ? ? 2.028 ? disulf7 disulf ? ? A CYS 608 SG ? ? ? 1_555 A CYS 623 SG ? ? A CYS 635 A CYS 650 1_555 ? ? ? ? ? ? ? 2.032 ? disulf8 disulf ? ? A CYS 728 SG ? ? ? 1_555 A CYS 754 SG ? ? A CYS 755 A CYS 781 1_555 ? ? ? ? ? ? ? 2.033 ? disulf9 disulf ? ? A CYS 730 SG ? ? ? 1_555 A CYS 772 SG ? ? A CYS 757 A CYS 799 1_555 ? ? ? ? ? ? ? 2.037 ? disulf10 disulf ? ? B CYS 10 SG ? ? ? 1_555 B CYS 68 SG ? ? J CYS 10 J CYS 68 1_555 ? ? ? ? ? ? ? 2.028 ? disulf11 disulf ? ? B CYS 47 SG ? ? ? 1_555 B CYS 99 SG ? ? J CYS 47 J CYS 99 1_555 ? ? ? ? ? ? ? 2.032 ? disulf12 disulf ? ? B CYS 54 SG ? ? ? 1_555 B CYS 101 SG ? ? J CYS 54 J CYS 101 1_555 ? ? ? ? ? ? ? 2.028 ? disulf13 disulf ? ? B CYS 98 SG ? ? ? 1_555 C CYS 98 SG ? ? J CYS 98 K CYS 98 1_555 ? ? ? ? ? ? ? 2.027 ? disulf14 disulf ? ? C CYS 10 SG ? ? ? 1_555 C CYS 68 SG ? ? K CYS 10 K CYS 68 1_555 ? ? ? ? ? ? ? 2.029 ? disulf15 disulf ? ? C CYS 47 SG ? ? ? 1_555 C CYS 99 SG ? ? K CYS 47 K CYS 99 1_555 ? ? ? ? ? ? ? 2.024 ? disulf16 disulf ? ? C CYS 54 SG ? ? ? 1_555 C CYS 101 SG ? ? K CYS 54 K CYS 101 1_555 ? ? ? ? ? ? ? 2.035 ? covale1 covale ? ? E NAG . O4 ? ? ? 1_555 F BMA . C1 ? ? A NAG 2002 A BMA 2003 1_555 ? ? ? ? ? ? ? 1.430 ? covale2 covale ? ? A ASN 364 ND2 ? ? ? 1_555 V NAG . C1 ? ? A ASN 391 A NAG 2019 1_555 ? ? ? ? ? ? ? 1.435 ? covale3 covale ? ? A ASN 676 ND2 ? ? ? 1_555 T NAG . C1 ? ? A ASN 703 A NAG 2017 1_555 ? ? ? ? ? ? ? 1.436 ? covale4 covale ? ? T NAG . O4 ? ? ? 1_555 U NAG . C1 ? ? A NAG 2017 A NAG 2018 1_555 ? ? ? ? ? ? ? 1.436 ? covale5 covale ? ? F BMA . O3 ? ? ? 1_555 G BMA . C1 ? ? A BMA 2003 A BMA 2004 1_555 ? ? ? ? ? ? ? 1.438 ? covale6 covale ? ? G BMA . O3 ? ? ? 1_555 H MAN . C1 ? ? A BMA 2004 A MAN 2005 1_555 ? ? ? ? ? ? ? 1.438 ? covale7 covale ? ? A ASN 53 ND2 ? ? ? 1_555 J NAG . C1 ? ? A ASN 80 A NAG 2007 1_555 ? ? ? ? ? ? ? 1.439 ? covale8 covale ? ? A ASN 148 ND2 ? ? ? 1_555 Y NAG . C1 ? ? A ASN 175 A NAG 2022 1_555 ? ? ? ? ? ? ? 1.439 ? covale9 covale ? ? A ASN 501 ND2 ? ? ? 1_555 M NAG . C1 ? ? A ASN 528 A NAG 2010 1_555 ? ? ? ? ? ? ? 1.443 ? covale10 covale ? ? K NAG . O4 ? ? ? 1_555 L NAG . C1 ? ? A NAG 2008 A NAG 2009 1_555 ? ? ? ? ? ? ? 1.443 ? covale11 covale ? ? N NAG . O4 ? ? ? 1_555 O BMA . C1 ? ? A NAG 2011 A BMA 2012 1_555 ? ? ? ? ? ? ? 1.443 ? covale12 covale ? ? A ASN 243 ND2 ? ? ? 1_555 R NAG . C1 ? ? A ASN 270 A NAG 2015 1_555 ? ? ? ? ? ? ? 1.444 ? covale13 covale ? ? A ASN 208 ND2 ? ? ? 1_555 I NAG . C1 ? ? A ASN 235 A NAG 2006 1_555 ? ? ? ? ? ? ? 1.445 ? covale14 covale ? ? A ASN 113 ND2 ? ? ? 1_555 P NAG . C1 ? ? A ASN 140 A NAG 2013 1_555 ? ? ? ? ? ? ? 1.446 ? covale15 covale ? ? A ASN 319 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 346 A NAG 2001 1_555 ? ? ? ? ? ? ? 1.446 ? covale16 covale ? ? A ASN 455 ND2 ? ? ? 1_555 K NAG . C1 ? ? A ASN 482 A NAG 2008 1_555 ? ? ? ? ? ? ? 1.446 ? covale17 covale ? ? M NAG . O4 ? ? ? 1_555 N NAG . C1 ? ? A NAG 2010 A NAG 2011 1_555 ? ? ? ? ? ? ? 1.447 ? covale18 covale ? ? R NAG . O4 ? ? ? 1_555 S NAG . C1 ? ? A NAG 2015 A NAG 2016 1_555 ? ? ? ? ? ? ? 1.449 ? covale19 covale ? ? A ASN 627 ND2 ? ? ? 1_555 Z NAG . C1 ? ? A ASN 654 A NAG 2023 1_555 ? ? ? ? ? ? ? 1.451 ? covale20 covale ? ? P NAG . O4 ? ? ? 1_555 Q NAG . C1 ? ? A NAG 2013 A NAG 2014 1_555 ? ? ? ? ? ? ? 1.451 ? covale21 covale ? ? A ASN 481 ND2 ? ? ? 1_555 X NAG . C1 ? ? A ASN 508 A NAG 2021 1_555 ? ? ? ? ? ? ? 1.452 ? covale22 covale ? ? V NAG . O4 ? ? ? 1_555 W NAG . C1 ? ? A NAG 2019 A NAG 2020 1_555 ? ? ? ? ? ? ? 1.453 ? covale23 covale ? ? D NAG . O4 ? ? ? 1_555 E NAG . C1 ? ? A NAG 2001 A NAG 2002 1_555 ? ? ? ? ? ? ? 1.459 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ASP 13 A . ? ASP 40 A GLY 14 A ? GLY 41 A 1 -3.02 2 CYS 29 A . ? CYS 56 A PRO 30 A ? PRO 57 A 1 -2.12 3 GLN 572 A . ? GLN 599 A PRO 573 A ? PRO 600 A 1 1.10 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 15 ? B ? 2 ? C ? 9 ? D ? 2 ? E ? 5 ? F ? 2 ? G ? 2 ? H ? 3 ? I ? 2 ? J ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel A 4 5 ? parallel A 5 6 ? parallel A 6 7 ? parallel A 7 8 ? parallel A 8 9 ? parallel A 9 10 ? parallel A 10 11 ? parallel A 11 12 ? parallel A 12 13 ? parallel A 13 14 ? parallel A 14 15 ? parallel B 1 2 ? parallel C 1 2 ? parallel C 2 3 ? parallel C 3 4 ? parallel C 4 5 ? parallel C 5 6 ? parallel C 6 7 ? parallel C 7 8 ? parallel C 8 9 ? parallel D 1 2 ? parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? parallel E 4 5 ? parallel F 1 2 ? parallel G 1 2 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel I 1 2 ? anti-parallel J 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 PRO A 20 ? ILE A 21 ? PRO A 47 ILE A 48 A 2 GLU A 24 ? GLU A 26 ? GLU A 51 GLU A 53 A 3 PHE A 38 ? GLN A 43 ? PHE A 65 GLN A 70 A 4 TYR A 47 ? CYS A 52 ? TYR A 74 CYS A 79 A 5 ARG A 74 ? ARG A 78 ? ARG A 101 ARG A 105 A 6 THR A 102 ? GLU A 106 ? THR A 129 GLU A 133 A 7 ARG A 127 ? THR A 131 ? ARG A 154 THR A 158 A 8 HIS A 151 ? ARG A 155 ? HIS A 178 ARG A 182 A 9 SER A 174 ? GLU A 176 ? SER A 201 GLU A 203 A 10 GLN A 198 ? ASN A 200 ? GLN A 225 ASN A 227 A 11 GLY A 222 ? ASP A 224 ? GLY A 249 ASP A 251 A 12 ASP A 246 ? ASN A 248 ? ASP A 273 ASN A 275 A 13 GLU A 270 ? LEU A 273 ? GLU A 297 LEU A 300 A 14 ILE A 296 ? LEU A 299 ? ILE A 323 LEU A 326 A 15 ILE A 320 ? SER A 321 ? ILE A 347 SER A 348 B 1 GLY A 70 ? GLU A 71 ? GLY A 97 GLU A 98 B 2 ILE A 97 ? VAL A 98 ? ILE A 124 VAL A 125 C 1 SER A 343 ? ASP A 345 ? SER A 370 ASP A 372 C 2 ASP A 367 ? ARG A 369 ? ASP A 394 ARG A 396 C 3 THR A 391 ? VAL A 393 ? THR A 418 VAL A 420 C 4 HIS A 415 ? HIS A 417 ? HIS A 442 HIS A 444 C 5 THR A 450 ? ASN A 452 ? THR A 477 ASN A 479 C 6 GLU A 474 ? ASP A 476 ? GLU A 501 ASP A 503 C 7 LEU A 498 ? ASN A 501 ? LEU A 525 ASN A 528 C 8 VAL A 527 ? ASP A 530 ? VAL A 554 ASP A 557 C 9 PHE A 561 ? ARG A 564 ? PHE A 588 ARG A 591 D 1 SER A 484 ? GLY A 486 ? SER A 511 GLY A 513 D 2 ARG A 509 ? ALA A 511 ? ARG A 536 ALA A 538 E 1 ILE A 590 ? CYS A 591 ? ILE A 617 CYS A 618 E 2 ASN A 609 ? ARG A 613 ? ASN A 636 ARG A 640 E 3 ALA A 618 ? ASN A 622 ? ALA A 645 ASN A 649 E 4 LEU A 643 ? HIS A 647 ? LEU A 670 HIS A 674 E 5 SER A 669 ? HIS A 671 ? SER A 696 HIS A 698 F 1 HIS A 691 ? ASP A 693 ? HIS A 718 ASP A 720 F 2 SER A 718 ? LYS A 720 ? SER A 745 LYS A 747 G 1 LYS B 15 ? LEU B 16 ? LYS J 15 LEU J 16 G 2 GLN B 43 ? ILE B 44 ? GLN J 43 ILE J 44 H 1 ASN B 65 ? THR B 73 ? ASN J 65 THR J 73 H 2 ILE B 95 ? LYS B 104 ? ILE J 95 LYS J 104 H 3 GLU C 6 ? PHE C 8 ? GLU K 6 PHE K 8 I 1 SER C 12 ? LYS C 15 ? SER K 12 LYS K 15 I 2 ILE C 44 ? CYS C 47 ? ILE K 44 CYS K 47 J 1 ILE C 67 ? TYR C 72 ? ILE K 67 TYR K 72 J 2 PRO C 96 ? ALA C 102 ? PRO K 96 ALA K 102 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N ILE A 21 ? N ILE A 48 O GLU A 24 ? O GLU A 51 A 2 3 N TYR A 25 ? N TYR A 52 O ILE A 42 ? O ILE A 69 A 3 4 N THR A 41 ? N THR A 68 O GLN A 49 ? O GLN A 76 A 4 5 N ILE A 50 ? N ILE A 77 O GLN A 76 ? O GLN A 103 A 5 6 N VAL A 75 ? N VAL A 102 O THR A 102 ? O THR A 129 A 6 7 N PHE A 105 ? N PHE A 132 O ARG A 129 ? O ARG A 156 A 7 8 N PHE A 130 ? N PHE A 157 O ARG A 155 ? O ARG A 182 A 8 9 N LEU A 152 ? N LEU A 179 O GLU A 176 ? O GLU A 203 A 9 10 N ILE A 175 ? N ILE A 202 O ASN A 200 ? O ASN A 227 A 10 11 N LEU A 199 ? N LEU A 226 O GLY A 222 ? O GLY A 249 A 11 12 N ILE A 223 ? N ILE A 250 O ASP A 246 ? O ASP A 273 A 12 13 N ILE A 247 ? N ILE A 274 O GLU A 270 ? O GLU A 297 A 13 14 N LEU A 273 ? N LEU A 300 O ARG A 298 ? O ARG A 325 A 14 15 N LEU A 299 ? N LEU A 326 O SER A 321 ? O SER A 348 B 1 2 N GLY A 70 ? N GLY A 97 O VAL A 98 ? O VAL A 125 C 1 2 N LEU A 344 ? N LEU A 371 O ARG A 369 ? O ARG A 396 C 2 3 N LEU A 368 ? N LEU A 395 O VAL A 393 ? O VAL A 420 C 3 4 N LEU A 392 ? N LEU A 419 O HIS A 415 ? O HIS A 442 C 4 5 N LEU A 416 ? N LEU A 443 O THR A 450 ? O THR A 477 C 5 6 N LEU A 451 ? N LEU A 478 O GLU A 474 ? O GLU A 501 C 6 7 N LEU A 475 ? N LEU A 502 O ASN A 501 ? O ASN A 528 C 7 8 N LEU A 498 ? N LEU A 525 O HIS A 528 ? O HIS A 555 C 8 9 N VAL A 527 ? N VAL A 554 O LYS A 562 ? O LYS A 589 D 1 2 N LEU A 485 ? N LEU A 512 O ALA A 511 ? O ALA A 538 E 1 2 N CYS A 591 ? N CYS A 618 O VAL A 612 ? O VAL A 639 E 2 3 N ASN A 609 ? N ASN A 636 O ASN A 622 ? O ASN A 649 E 3 4 N LEU A 619 ? N LEU A 646 O LEU A 643 ? O LEU A 670 E 4 5 N MET A 644 ? N MET A 671 O SER A 669 ? O SER A 696 F 1 2 N LEU A 692 ? N LEU A 719 O LYS A 720 ? O LYS A 747 G 1 2 N LYS B 15 ? N LYS J 15 O ILE B 44 ? O ILE J 44 H 1 2 N LYS B 69 ? N LYS J 69 O LYS B 100 ? O LYS J 100 H 2 3 N LEU B 103 ? N LEU J 103 O ARG C 7 ? O ARG K 7 I 1 2 N ILE C 13 ? N ILE K 13 O GLU C 46 ? O GLU K 46 J 1 2 N LYS C 69 ? N LYS K 69 O LYS C 100 ? O LYS K 100 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE EPE A 2024' AC2 Software ? ? ? ? 3 'BINDING SITE FOR MONO-SACCHARIDE NAG A2007 BOUND TO ASN A 80' AC3 Software ? ? ? ? 3 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 140 RESIDUES 2013 TO 2014' AC4 Software ? ? ? ? 5 'BINDING SITE FOR MONO-SACCHARIDE NAG A2022 BOUND TO ASN A 175' AC5 Software ? ? ? ? 2 'BINDING SITE FOR MONO-SACCHARIDE NAG A2006 BOUND TO ASN A 235' AC6 Software ? ? ? ? 6 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 270 RESIDUES 2015 TO 2016' AC7 Software ? ? ? ? 9 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 346 RESIDUES 2001 TO 2005' AC8 Software ? ? ? ? 3 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 391 RESIDUES 2019 TO 2020' AC9 Software ? ? ? ? 5 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 482 RESIDUES 2008 TO 2009' BC1 Software ? ? ? ? 2 'BINDING SITE FOR MONO-SACCHARIDE NAG A2021 BOUND TO ASN A 508' BC2 Software ? ? ? ? 6 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 528 RESIDUES 2010 TO 2012' BC3 Software ? ? ? ? 4 'BINDING SITE FOR MONO-SACCHARIDE NAG A2023 BOUND TO ASN A 654' BC4 Software ? ? ? ? 3 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 703 RESIDUES 2017 TO 2018' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 10 ARG A 133 ? ARG A 160 . ? 1_555 ? 2 AC1 10 ASN A 157 ? ASN A 184 . ? 1_555 ? 3 AC1 10 ASN A 180 ? ASN A 207 . ? 1_555 ? 4 AC1 10 SER A 203 ? SER A 230 . ? 1_555 ? 5 AC1 10 ASN A 204 ? ASN A 231 . ? 1_555 ? 6 AC1 10 GLN A 205 ? GLN A 232 . ? 1_555 ? 7 AC1 10 ARG A 749 ? ARG A 776 . ? 2_556 ? 8 AC1 10 ASN A 750 ? ASN A 777 . ? 2_556 ? 9 AC1 10 ARG A 762 ? ARG A 789 . ? 2_556 ? 10 AC1 10 VAL A 764 ? VAL A 791 . ? 2_556 ? 11 AC2 3 ASN A 35 ? ASN A 62 . ? 1_555 ? 12 AC2 3 ASN A 53 ? ASN A 80 . ? 1_555 ? 13 AC2 3 ARG A 79 ? ARG A 106 . ? 1_555 ? 14 AC3 3 MET A 112 ? MET A 139 . ? 1_555 ? 15 AC3 3 ASN A 113 ? ASN A 140 . ? 1_555 ? 16 AC3 3 ARG A 187 ? ARG A 214 . ? 2_455 ? 17 AC4 5 HIS A 123 ? HIS A 150 . ? 1_555 ? 18 AC4 5 GLY A 124 ? GLY A 151 . ? 1_555 ? 19 AC4 5 ASN A 148 ? ASN A 175 . ? 1_555 ? 20 AC4 5 ASP A 381 ? ASP A 408 . ? 4_455 ? 21 AC4 5 ARG A 405 ? ARG A 432 . ? 4_455 ? 22 AC5 2 ASN A 208 ? ASN A 235 . ? 1_555 ? 23 AC5 2 GLU A 231 ? GLU A 258 . ? 1_555 ? 24 AC6 6 THR A 242 ? THR A 269 . ? 1_555 ? 25 AC6 6 ASN A 243 ? ASN A 270 . ? 1_555 ? 26 AC6 6 THR A 376 ? THR A 403 . ? 4_455 ? 27 AC6 6 ARG A 398 ? ARG A 425 . ? 4_455 ? 28 AC6 6 ASP A 422 ? ASP A 449 . ? 4_455 ? 29 AC6 6 NAG L . ? NAG A 2009 . ? 4_455 ? 30 AC7 9 ILE A 296 ? ILE A 323 . ? 1_555 ? 31 AC7 9 ARG A 298 ? ARG A 325 . ? 1_555 ? 32 AC7 9 ASN A 319 ? ASN A 346 . ? 1_555 ? 33 AC7 9 SER A 343 ? SER A 370 . ? 1_555 ? 34 AC7 9 ASP A 367 ? ASP A 394 . ? 1_555 ? 35 AC7 9 GLU B 48 ? GLU J 48 . ? 1_555 ? 36 AC7 9 GLY B 49 ? GLY J 49 . ? 1_555 ? 37 AC7 9 ALA B 50 ? ALA J 50 . ? 1_555 ? 38 AC7 9 GLN B 52 ? GLN J 52 . ? 1_555 ? 39 AC8 3 ASN A 340 ? ASN A 367 . ? 1_555 ? 40 AC8 3 THR A 363 ? THR A 390 . ? 1_555 ? 41 AC8 3 ASN A 364 ? ASN A 391 . ? 1_555 ? 42 AC9 5 ARG A 398 ? ARG A 425 . ? 1_555 ? 43 AC9 5 HIS A 420 ? HIS A 447 . ? 1_555 ? 44 AC9 5 ASN A 455 ? ASN A 482 . ? 1_555 ? 45 AC9 5 TYR A 479 ? TYR A 506 . ? 1_555 ? 46 AC9 5 NAG S . ? NAG A 2016 . ? 4_445 ? 47 BC1 2 SER A 457 ? SER A 484 . ? 1_555 ? 48 BC1 2 ASN A 481 ? ASN A 508 . ? 1_555 ? 49 BC2 6 ARG A 454 ? ARG A 481 . ? 1_555 ? 50 BC2 6 ASN A 501 ? ASN A 528 . ? 1_555 ? 51 BC2 6 THR A 503 ? THR A 530 . ? 1_555 ? 52 BC2 6 HIS A 504 ? HIS A 531 . ? 1_555 ? 53 BC2 6 ASP A 530 ? ASP A 557 . ? 1_555 ? 54 BC2 6 ARG A 567 ? ARG A 594 . ? 1_555 ? 55 BC3 4 ASP A 5 ? ASP A 32 . ? 2_546 ? 56 BC3 4 SER A 625 ? SER A 652 . ? 1_555 ? 57 BC3 4 ASN A 627 ? ASN A 654 . ? 1_555 ? 58 BC3 4 LEU A 628 ? LEU A 655 . ? 1_555 ? 59 BC4 3 GLU A 71 ? GLU A 98 . ? 2_546 ? 60 BC4 3 ASN A 676 ? ASN A 703 . ? 1_555 ? 61 BC4 3 HIS A 698 ? HIS A 725 . ? 1_555 ? # _atom_sites.entry_id 4LXS _atom_sites.fract_transf_matrix[1][1] 0.005838 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.004287 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.013017 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.010020 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . SER A 1 1 ? -68.395 7.349 25.209 1.00 32.75 ? 28 SER A N 1 ATOM 2 C CA . SER A 1 1 ? -69.801 6.963 25.212 1.00 40.54 ? 28 SER A CA 1 ATOM 3 C C . SER A 1 1 ? -70.158 6.232 26.494 1.00 36.91 ? 28 SER A C 1 ATOM 4 O O . SER A 1 1 ? -71.049 6.649 27.232 1.00 40.85 ? 28 SER A O 1 ATOM 5 C CB . SER A 1 1 ? -70.123 6.075 24.009 1.00 41.04 ? 28 SER A CB 1 ATOM 6 O OG . SER A 1 1 ? -70.057 6.798 22.790 1.00 39.62 ? 28 SER A OG 1 ATOM 7 N N . PHE A 1 2 ? -69.469 5.125 26.745 1.00 32.68 ? 29 PHE A N 1 ATOM 8 C CA . PHE A 1 2 ? -69.631 4.403 27.995 1.00 34.83 ? 29 PHE A CA 1 ATOM 9 C C . PHE A 1 2 ? -68.273 4.175 28.624 1.00 39.84 ? 29 PHE A C 1 ATOM 10 O O . PHE A 1 2 ? -67.425 3.492 28.052 1.00 39.31 ? 29 PHE A O 1 ATOM 11 C CB . PHE A 1 2 ? -70.326 3.063 27.771 1.00 32.65 ? 29 PHE A CB 1 ATOM 12 C CG . PHE A 1 2 ? -70.415 2.217 29.009 1.00 33.61 ? 29 PHE A CG 1 ATOM 13 C CD1 . PHE A 1 2 ? -71.455 2.388 29.906 1.00 33.80 ? 29 PHE A CD1 1 ATOM 14 C CD2 . PHE A 1 2 ? -69.460 1.251 29.276 1.00 29.29 ? 29 PHE A CD2 1 ATOM 15 C CE1 . PHE A 1 2 ? -71.540 1.614 31.044 1.00 30.09 ? 29 PHE A CE1 1 ATOM 16 C CE2 . PHE A 1 2 ? -69.541 0.477 30.412 1.00 30.44 ? 29 PHE A CE2 1 ATOM 17 C CZ . PHE A 1 2 ? -70.582 0.658 31.297 1.00 29.71 ? 29 PHE A CZ 1 ATOM 18 N N . GLY A 1 3 ? -68.069 4.745 29.805 1.00 49.03 ? 30 GLY A N 1 ATOM 19 C CA . GLY A 1 3 ? -66.799 4.606 30.492 1.00 60.85 ? 30 GLY A CA 1 ATOM 20 C C . GLY A 1 3 ? -66.934 4.254 31.960 1.00 58.73 ? 30 GLY A C 1 ATOM 21 O O . GLY A 1 3 ? -68.011 3.880 32.431 1.00 57.68 ? 30 GLY A O 1 ATOM 22 N N . ARG A 1 4 ? -65.823 4.382 32.679 1.00 56.36 ? 31 ARG A N 1 ATOM 23 C CA . ARG A 1 4 ? -65.761 4.106 34.111 1.00 64.01 ? 31 ARG A CA 1 ATOM 24 C C . ARG A 1 4 ? -66.814 4.878 34.892 1.00 59.69 ? 31 ARG A C 1 ATOM 25 O O . ARG A 1 4 ? -67.300 4.419 35.928 1.00 57.36 ? 31 ARG A O 1 ATOM 26 C CB . ARG A 1 4 ? -64.369 4.466 34.633 1.00 74.27 ? 31 ARG A CB 1 ATOM 27 C CG . ARG A 1 4 ? -64.185 4.352 36.137 1.00 67.03 ? 31 ARG A CG 1 ATOM 28 C CD . ARG A 1 4 ? -62.738 4.635 36.525 1.00 79.51 ? 31 ARG A CD 1 ATOM 29 N NE . ARG A 1 4 ? -61.835 3.539 36.169 1.00 90.13 ? 31 ARG A NE 1 ATOM 30 C CZ . ARG A 1 4 ? -61.230 3.406 34.990 1.00 87.83 ? 31 ARG A CZ 1 ATOM 31 N NH1 . ARG A 1 4 ? -61.432 4.299 34.028 1.00 81.92 1 31 ARG A NH1 1 ATOM 32 N NH2 . ARG A 1 4 ? -60.427 2.373 34.769 1.00 84.25 ? 31 ARG A NH2 1 ATOM 33 N N . ASP A 1 5 ? -67.165 6.054 34.384 1.00 55.30 ? 32 ASP A N 1 ATOM 34 C CA . ASP A 1 5 ? -68.102 6.917 35.077 1.00 53.97 ? 32 ASP A CA 1 ATOM 35 C C . ASP A 1 5 ? -69.499 6.311 35.102 1.00 50.35 ? 32 ASP A C 1 ATOM 36 O O . ASP A 1 5 ? -70.154 6.285 36.143 1.00 53.77 ? 32 ASP A O 1 ATOM 37 C CB . ASP A 1 5 ? -68.132 8.296 34.434 1.00 54.03 ? 32 ASP A CB 1 ATOM 38 C CG . ASP A 1 5 ? -68.871 9.300 35.278 1.00 62.25 ? 32 ASP A CG 1 ATOM 39 O OD1 . ASP A 1 5 ? -68.487 9.492 36.452 1.00 58.35 ? 32 ASP A OD1 1 ATOM 40 O OD2 . ASP A 1 5 ? -69.855 9.876 34.775 1.00 65.94 1 32 ASP A OD2 1 ATOM 41 N N . ALA A 1 6 ? -69.946 5.821 33.952 1.00 47.46 ? 33 ALA A N 1 ATOM 42 C CA . ALA A 1 6 ? -71.244 5.168 33.855 1.00 45.67 ? 33 ALA A CA 1 ATOM 43 C C . ALA A 1 6 ? -71.220 3.874 34.653 1.00 45.13 ? 33 ALA A C 1 ATOM 44 O O . ALA A 1 6 ? -72.215 3.469 35.259 1.00 43.90 ? 33 ALA A O 1 ATOM 45 C CB . ALA A 1 6 ? -71.571 4.884 32.407 1.00 41.71 ? 33 ALA A CB 1 ATOM 46 N N . CYS A 1 7 ? -70.054 3.243 34.648 1.00 46.75 ? 34 CYS A N 1 ATOM 47 C CA . CYS A 1 7 ? -69.838 1.955 35.285 1.00 45.65 ? 34 CYS A CA 1 ATOM 48 C C . CYS A 1 7 ? -70.119 2.003 36.788 1.00 52.06 ? 34 CYS A C 1 ATOM 49 O O . CYS A 1 7 ? -70.811 1.140 37.329 1.00 55.02 ? 34 CYS A O 1 ATOM 50 C CB . CYS A 1 7 ? -68.397 1.512 35.023 1.00 45.55 ? 34 CYS A CB 1 ATOM 51 S SG . CYS A 1 7 ? -68.026 -0.200 35.401 1.00 39.76 ? 34 CYS A SG 1 ATOM 52 N N . SER A 1 8 ? -69.585 3.022 37.451 1.00 52.80 ? 35 SER A N 1 ATOM 53 C CA . SER A 1 8 ? -69.723 3.170 38.895 1.00 52.49 ? 35 SER A CA 1 ATOM 54 C C . SER A 1 8 ? -71.182 3.307 39.327 1.00 56.56 ? 35 SER A C 1 ATOM 55 O O . SER A 1 8 ? -71.566 2.864 40.410 1.00 63.39 ? 35 SER A O 1 ATOM 56 C CB . SER A 1 8 ? -68.935 4.391 39.362 1.00 62.31 ? 35 SER A CB 1 ATOM 57 O OG . SER A 1 8 ? -69.415 5.564 38.729 1.00 60.90 ? 35 SER A OG 1 ATOM 58 N N . GLU A 1 9 ? -71.989 3.922 38.472 1.00 52.10 ? 36 GLU A N 1 ATOM 59 C CA . GLU A 1 9 ? -73.392 4.154 38.780 1.00 52.80 ? 36 GLU A CA 1 ATOM 60 C C . GLU A 1 9 ? -74.208 2.868 38.674 1.00 56.63 ? 36 GLU A C 1 ATOM 61 O O . GLU A 1 9 ? -73.926 1.997 37.851 1.00 52.25 ? 36 GLU A O 1 ATOM 62 C CB . GLU A 1 9 ? -73.953 5.219 37.844 1.00 55.38 ? 36 GLU A CB 1 ATOM 63 C CG . GLU A 1 9 ? -73.077 6.458 37.748 1.00 57.41 ? 36 GLU A CG 1 ATOM 64 C CD . GLU A 1 9 ? -73.492 7.381 36.619 1.00 63.99 ? 36 GLU A CD 1 ATOM 65 O OE1 . GLU A 1 9 ? -72.863 8.448 36.459 1.00 63.75 ? 36 GLU A OE1 1 ATOM 66 O OE2 . GLU A 1 9 ? -74.447 7.037 35.889 1.00 69.97 1 36 GLU A OE2 1 ATOM 67 N N . ASP A 1 13 ? -77.689 1.137 39.392 1.00 62.90 ? 40 ASP A N 1 ATOM 68 C CA . ASP A 1 13 ? -77.545 1.677 40.739 1.00 76.05 ? 40 ASP A CA 1 ATOM 69 C C . ASP A 1 13 ? -78.890 1.959 41.415 1.00 81.41 ? 40 ASP A C 1 ATOM 70 O O . ASP A 1 13 ? -79.326 3.109 41.469 1.00 78.52 ? 40 ASP A O 1 ATOM 71 C CB . ASP A 1 13 ? -76.728 2.966 40.688 1.00 74.86 ? 40 ASP A CB 1 ATOM 72 C CG . ASP A 1 13 ? -76.432 3.524 42.059 1.00 89.28 ? 40 ASP A CG 1 ATOM 73 O OD1 . ASP A 1 13 ? -76.284 2.725 43.008 1.00 96.46 1 40 ASP A OD1 1 ATOM 74 O OD2 . ASP A 1 13 ? -76.348 4.763 42.186 1.00 89.55 ? 40 ASP A OD2 1 ATOM 75 N N . GLY A 1 14 ? -79.550 0.924 41.930 1.00 79.09 ? 41 GLY A N 1 ATOM 76 C CA . GLY A 1 14 ? -79.084 -0.445 41.821 1.00 74.20 ? 41 GLY A CA 1 ATOM 77 C C . GLY A 1 14 ? -79.848 -1.179 40.736 1.00 73.28 ? 41 GLY A C 1 ATOM 78 O O . GLY A 1 14 ? -80.939 -1.697 40.967 1.00 74.73 ? 41 GLY A O 1 ATOM 79 N N . LEU A 1 15 ? -79.271 -1.204 39.542 1.00 66.09 ? 42 LEU A N 1 ATOM 80 C CA . LEU A 1 15 ? -79.851 -1.892 38.400 1.00 56.66 ? 42 LEU A CA 1 ATOM 81 C C . LEU A 1 15 ? -79.074 -3.183 38.213 1.00 51.21 ? 42 LEU A C 1 ATOM 82 O O . LEU A 1 15 ? -79.452 -4.241 38.719 1.00 42.50 ? 42 LEU A O 1 ATOM 83 C CB . LEU A 1 15 ? -79.719 -1.005 37.157 1.00 60.99 ? 42 LEU A CB 1 ATOM 84 C CG . LEU A 1 15 ? -80.059 -1.509 35.749 1.00 67.82 ? 42 LEU A CG 1 ATOM 85 C CD1 . LEU A 1 15 ? -81.561 -1.491 35.466 1.00 53.18 ? 42 LEU A CD1 1 ATOM 86 C CD2 . LEU A 1 15 ? -79.284 -0.701 34.707 1.00 55.66 ? 42 LEU A CD2 1 ATOM 87 N N . CYS A 1 16 ? -77.970 -3.074 37.488 1.00 47.54 ? 43 CYS A N 1 ATOM 88 C CA . CYS A 1 16 ? -77.022 -4.155 37.340 1.00 40.15 ? 43 CYS A CA 1 ATOM 89 C C . CYS A 1 16 ? -75.713 -3.542 37.764 1.00 38.04 ? 43 CYS A C 1 ATOM 90 O O . CYS A 1 16 ? -75.538 -2.328 37.649 1.00 45.52 ? 43 CYS A O 1 ATOM 91 C CB . CYS A 1 16 ? -76.941 -4.588 35.880 1.00 41.07 ? 43 CYS A CB 1 ATOM 92 S SG . CYS A 1 16 ? -78.490 -5.225 35.206 1.00 49.88 ? 43 CYS A SG 1 ATOM 93 N N . GLN A 1 17 ? -74.791 -4.353 38.263 1.00 31.17 ? 44 GLN A N 1 ATOM 94 C CA . GLN A 1 17 ? -73.522 -3.805 38.721 1.00 38.65 ? 44 GLN A CA 1 ATOM 95 C C . GLN A 1 17 ? -72.435 -3.878 37.657 1.00 33.31 ? 44 GLN A C 1 ATOM 96 O O . GLN A 1 17 ? -72.309 -4.868 36.943 1.00 33.09 ? 44 GLN A O 1 ATOM 97 C CB . GLN A 1 17 ? -73.057 -4.491 40.003 1.00 40.05 ? 44 GLN A CB 1 ATOM 98 C CG . GLN A 1 17 ? -72.651 -5.937 39.821 1.00 40.62 ? 44 GLN A CG 1 ATOM 99 C CD . GLN A 1 17 ? -72.261 -6.581 41.126 1.00 36.53 ? 44 GLN A CD 1 ATOM 100 O OE1 . GLN A 1 17 ? -72.378 -5.970 42.185 1.00 38.94 ? 44 GLN A OE1 1 ATOM 101 N NE2 . GLN A 1 17 ? -71.800 -7.823 41.061 1.00 37.70 ? 44 GLN A NE2 1 ATOM 102 N N . CYS A 1 18 ? -71.654 -2.811 37.557 1.00 29.50 ? 45 CYS A N 1 ATOM 103 C CA . CYS A 1 18 ? -70.535 -2.770 36.637 1.00 27.02 ? 45 CYS A CA 1 ATOM 104 C C . CYS A 1 18 ? -69.240 -2.643 37.425 1.00 37.70 ? 45 CYS A C 1 ATOM 105 O O . CYS A 1 18 ? -69.211 -2.042 38.498 1.00 44.84 ? 45 CYS A O 1 ATOM 106 C CB . CYS A 1 18 ? -70.689 -1.593 35.679 1.00 35.29 ? 45 CYS A CB 1 ATOM 107 S SG . CYS A 1 18 ? -69.351 -1.420 34.476 1.00 47.98 ? 45 CYS A SG 1 ATOM 108 N N . ALA A 1 19 ? -68.168 -3.208 36.889 1.00 34.41 ? 46 ALA A N 1 ATOM 109 C CA . ALA A 1 19 ? -66.877 -3.167 37.556 1.00 34.34 ? 46 ALA A CA 1 ATOM 110 C C . ALA A 1 19 ? -65.764 -3.227 36.523 1.00 41.98 ? 46 ALA A C 1 ATOM 111 O O . ALA A 1 19 ? -65.565 -4.259 35.889 1.00 46.67 ? 46 ALA A O 1 ATOM 112 C CB . ALA A 1 19 ? -66.758 -4.320 38.533 1.00 34.05 ? 46 ALA A CB 1 ATOM 113 N N . PRO A 1 20 ? -65.030 -2.119 36.352 1.00 45.26 ? 47 PRO A N 1 ATOM 114 C CA . PRO A 1 20 ? -64.003 -2.035 35.307 1.00 45.37 ? 47 PRO A CA 1 ATOM 115 C C . PRO A 1 20 ? -62.820 -2.953 35.582 1.00 41.29 ? 47 PRO A C 1 ATOM 116 O O . PRO A 1 20 ? -62.099 -2.740 36.550 1.00 42.38 ? 47 PRO A O 1 ATOM 117 C CB . PRO A 1 20 ? -63.558 -0.573 35.369 1.00 46.67 ? 47 PRO A CB 1 ATOM 118 C CG . PRO A 1 20 ? -63.863 -0.143 36.759 1.00 54.53 ? 47 PRO A CG 1 ATOM 119 C CD . PRO A 1 20 ? -65.092 -0.897 37.172 1.00 49.51 ? 47 PRO A CD 1 ATOM 120 N N . ILE A 1 21 ? -62.630 -3.965 34.742 1.00 44.51 ? 48 ILE A N 1 ATOM 121 C CA . ILE A 1 21 ? -61.474 -4.842 34.874 1.00 49.77 ? 48 ILE A CA 1 ATOM 122 C C . ILE A 1 21 ? -60.545 -4.689 33.673 1.00 52.34 ? 48 ILE A C 1 ATOM 123 O O . ILE A 1 21 ? -60.984 -4.325 32.577 1.00 43.24 ? 48 ILE A O 1 ATOM 124 C CB . ILE A 1 21 ? -61.875 -6.326 35.064 1.00 43.28 ? 48 ILE A CB 1 ATOM 125 C CG1 . ILE A 1 21 ? -61.958 -7.055 33.722 1.00 52.11 ? 48 ILE A CG1 1 ATOM 126 C CG2 . ILE A 1 21 ? -63.181 -6.429 35.834 1.00 39.73 ? 48 ILE A CG2 1 ATOM 127 C CD1 . ILE A 1 21 ? -62.325 -8.517 33.848 1.00 54.54 ? 48 ILE A CD1 1 ATOM 128 N N . MET A 1 22 ? -59.261 -4.958 33.900 1.00 55.83 ? 49 MET A N 1 ATOM 129 C CA . MET A 1 22 ? -58.233 -4.801 32.878 1.00 54.26 ? 49 MET A CA 1 ATOM 130 C C . MET A 1 22 ? -58.327 -3.433 32.210 1.00 54.29 ? 49 MET A C 1 ATOM 131 O O . MET A 1 22 ? -57.899 -2.423 32.767 1.00 64.78 ? 49 MET A O 1 ATOM 132 C CB . MET A 1 22 ? -58.338 -5.918 31.837 1.00 55.75 ? 49 MET A CB 1 ATOM 133 C CG . MET A 1 22 ? -58.037 -7.306 32.387 1.00 58.37 ? 49 MET A CG 1 ATOM 134 S SD . MET A 1 22 ? -56.309 -7.510 32.869 1.00 54.20 ? 49 MET A SD 1 ATOM 135 C CE . MET A 1 22 ? -56.291 -9.243 33.320 1.00 47.08 ? 49 MET A CE 1 ATOM 136 N N . SER A 1 23 ? -58.903 -3.408 31.016 1.00 43.12 ? 50 SER A N 1 ATOM 137 C CA . SER A 1 23 ? -59.128 -2.164 30.301 1.00 46.99 ? 50 SER A CA 1 ATOM 138 C C . SER A 1 23 ? -60.592 -2.100 29.882 1.00 50.85 ? 50 SER A C 1 ATOM 139 O O . SER A 1 23 ? -61.054 -1.113 29.306 1.00 41.95 ? 50 SER A O 1 ATOM 140 C CB . SER A 1 23 ? -58.216 -2.095 29.080 1.00 43.30 ? 50 SER A CB 1 ATOM 141 O OG . SER A 1 23 ? -58.195 -3.341 28.405 1.00 37.26 ? 50 SER A OG 1 ATOM 142 N N . GLU A 1 24 ? -61.319 -3.165 30.197 1.00 47.64 ? 51 GLU A N 1 ATOM 143 C CA . GLU A 1 24 ? -62.707 -3.298 29.788 1.00 42.41 ? 51 GLU A CA 1 ATOM 144 C C . GLU A 1 24 ? -63.665 -3.114 30.960 1.00 40.95 ? 51 GLU A C 1 ATOM 145 O O . GLU A 1 24 ? -63.286 -2.601 32.010 1.00 46.33 ? 51 GLU A O 1 ATOM 146 C CB . GLU A 1 24 ? -62.926 -4.663 29.131 1.00 44.16 ? 51 GLU A CB 1 ATOM 147 C CG . GLU A 1 24 ? -62.530 -5.843 30.003 1.00 38.70 ? 51 GLU A CG 1 ATOM 148 C CD . GLU A 1 24 ? -62.515 -7.149 29.236 1.00 38.10 ? 51 GLU A CD 1 ATOM 149 O OE1 . GLU A 1 24 ? -62.599 -8.218 29.878 1.00 40.36 ? 51 GLU A OE1 1 ATOM 150 O OE2 . GLU A 1 24 ? -62.413 -7.105 27.990 1.00 37.57 1 51 GLU A OE2 1 ATOM 151 N N . TYR A 1 25 ? -64.910 -3.535 30.768 1.00 35.43 ? 52 TYR A N 1 ATOM 152 C CA . TYR A 1 25 ? -65.939 -3.398 31.786 1.00 33.54 ? 52 TYR A CA 1 ATOM 153 C C . TYR A 1 25 ? -66.845 -4.621 31.775 1.00 34.14 ? 52 TYR A C 1 ATOM 154 O O . TYR A 1 25 ? -67.392 -4.977 30.732 1.00 31.83 ? 52 TYR A O 1 ATOM 155 C CB . TYR A 1 25 ? -66.779 -2.153 31.518 1.00 35.05 ? 52 TYR A CB 1 ATOM 156 C CG . TYR A 1 25 ? -65.999 -0.859 31.493 1.00 42.18 ? 52 TYR A CG 1 ATOM 157 C CD1 . TYR A 1 25 ? -65.763 -0.147 32.662 1.00 50.78 ? 52 TYR A CD1 1 ATOM 158 C CD2 . TYR A 1 25 ? -65.515 -0.338 30.299 1.00 42.77 ? 52 TYR A CD2 1 ATOM 159 C CE1 . TYR A 1 25 ? -65.056 1.044 32.645 1.00 53.53 ? 52 TYR A CE1 1 ATOM 160 C CE2 . TYR A 1 25 ? -64.808 0.855 30.273 1.00 50.54 ? 52 TYR A CE2 1 ATOM 161 C CZ . TYR A 1 25 ? -64.582 1.542 31.450 1.00 51.10 ? 52 TYR A CZ 1 ATOM 162 O OH . TYR A 1 25 ? -63.883 2.728 31.434 1.00 43.38 ? 52 TYR A OH 1 ATOM 163 N N . GLU A 1 26 ? -67.014 -5.250 32.935 1.00 28.09 ? 53 GLU A N 1 ATOM 164 C CA . GLU A 1 26 ? -67.811 -6.467 33.043 1.00 20.60 ? 53 GLU A CA 1 ATOM 165 C C . GLU A 1 26 ? -69.151 -6.223 33.720 1.00 19.53 ? 53 GLU A C 1 ATOM 166 O O . GLU A 1 26 ? -69.282 -6.433 34.922 1.00 21.20 ? 53 GLU A O 1 ATOM 167 C CB . GLU A 1 26 ? -67.047 -7.523 33.832 1.00 23.27 ? 53 GLU A CB 1 ATOM 168 C CG . GLU A 1 26 ? -67.741 -8.868 33.900 1.00 29.95 ? 53 GLU A CG 1 ATOM 169 C CD . GLU A 1 26 ? -67.122 -9.882 32.957 1.00 46.98 ? 53 GLU A CD 1 ATOM 170 O OE1 . GLU A 1 26 ? -66.197 -9.507 32.199 1.00 43.65 ? 53 GLU A OE1 1 ATOM 171 O OE2 . GLU A 1 26 ? -67.556 -11.056 32.980 1.00 43.38 1 53 GLU A OE2 1 ATOM 172 N N . ILE A 1 27 ? -70.147 -5.796 32.951 1.00 18.05 ? 54 ILE A N 1 ATOM 173 C CA . ILE A 1 27 ? -71.477 -5.542 33.497 1.00 18.41 ? 54 ILE A CA 1 ATOM 174 C C . ILE A 1 27 ? -72.243 -6.836 33.740 1.00 18.70 ? 54 ILE A C 1 ATOM 175 O O . ILE A 1 27 ? -72.221 -7.742 32.913 1.00 18.92 ? 54 ILE A O 1 ATOM 176 C CB . ILE A 1 27 ? -72.300 -4.637 32.583 1.00 18.25 ? 54 ILE A CB 1 ATOM 177 C CG1 . ILE A 1 27 ? -71.497 -3.386 32.227 1.00 22.31 ? 54 ILE A CG1 1 ATOM 178 C CG2 . ILE A 1 27 ? -73.619 -4.271 33.246 1.00 19.75 ? 54 ILE A CG2 1 ATOM 179 C CD1 . ILE A 1 27 ? -72.319 -2.301 31.581 1.00 25.08 ? 54 ILE A CD1 1 ATOM 180 N N . ILE A 1 28 ? -72.916 -6.914 34.883 1.00 20.84 ? 55 ILE A N 1 ATOM 181 C CA . ILE A 1 28 ? -73.588 -8.135 35.305 1.00 24.90 ? 55 ILE A CA 1 ATOM 182 C C . ILE A 1 28 ? -75.007 -7.827 35.721 1.00 34.66 ? 55 ILE A C 1 ATOM 183 O O . ILE A 1 28 ? -75.234 -7.105 36.693 1.00 40.27 ? 55 ILE A O 1 ATOM 184 C CB . ILE A 1 28 ? -72.885 -8.787 36.515 1.00 29.70 ? 55 ILE A CB 1 ATOM 185 C CG1 . ILE A 1 28 ? -71.459 -9.223 36.148 1.00 35.57 ? 55 ILE A CG1 1 ATOM 186 C CG2 . ILE A 1 28 ? -73.704 -9.961 37.027 1.00 27.71 ? 55 ILE A CG2 1 ATOM 187 C CD1 . ILE A 1 28 ? -70.601 -9.652 37.331 1.00 22.97 ? 55 ILE A CD1 1 ATOM 188 N N . CYS A 1 29 ? -75.962 -8.384 34.986 1.00 33.90 ? 56 CYS A N 1 ATOM 189 C CA . CYS A 1 29 ? -77.368 -8.195 35.301 1.00 31.05 ? 56 CYS A CA 1 ATOM 190 C C . CYS A 1 29 ? -78.039 -9.536 35.570 1.00 33.79 ? 56 CYS A C 1 ATOM 191 O O . CYS A 1 29 ? -77.952 -10.449 34.749 1.00 33.33 ? 56 CYS A O 1 ATOM 192 C CB . CYS A 1 29 ? -78.069 -7.458 34.166 1.00 28.99 ? 56 CYS A CB 1 ATOM 193 S SG . CYS A 1 29 ? -77.268 -5.903 33.739 1.00 36.73 ? 56 CYS A SG 1 ATOM 194 N N . PRO A 1 30 ? -78.703 -9.666 36.729 1.00 35.97 ? 57 PRO A N 1 ATOM 195 C CA . PRO A 1 30 ? -78.806 -8.650 37.781 1.00 34.83 ? 57 PRO A CA 1 ATOM 196 C C . PRO A 1 30 ? -77.495 -8.484 38.537 1.00 46.16 ? 57 PRO A C 1 ATOM 197 O O . PRO A 1 30 ? -76.578 -9.291 38.370 1.00 45.27 ? 57 PRO A O 1 ATOM 198 C CB . PRO A 1 30 ? -79.868 -9.224 38.726 1.00 34.76 ? 57 PRO A CB 1 ATOM 199 C CG . PRO A 1 30 ? -80.571 -10.271 37.950 1.00 31.91 ? 57 PRO A CG 1 ATOM 200 C CD . PRO A 1 30 ? -79.561 -10.827 37.008 1.00 35.40 ? 57 PRO A CD 1 ATOM 201 N N . ALA A 1 31 ? -77.423 -7.445 39.360 1.00 49.68 ? 58 ALA A N 1 ATOM 202 C CA . ALA A 1 31 ? -76.209 -7.120 40.093 1.00 47.87 ? 58 ALA A CA 1 ATOM 203 C C . ALA A 1 31 ? -75.819 -8.186 41.121 1.00 54.20 ? 58 ALA A C 1 ATOM 204 O O . ALA A 1 31 ? -74.637 -8.363 41.418 1.00 51.29 ? 58 ALA A O 1 ATOM 205 C CB . ALA A 1 31 ? -76.356 -5.764 40.761 1.00 50.91 ? 58 ALA A CB 1 ATOM 206 N N . ASN A 1 32 ? -76.802 -8.899 41.660 1.00 53.42 ? 59 ASN A N 1 ATOM 207 C CA . ASN A 1 32 ? -76.523 -9.867 42.720 1.00 65.97 ? 59 ASN A CA 1 ATOM 208 C C . ASN A 1 32 ? -76.769 -11.330 42.351 1.00 64.00 ? 59 ASN A C 1 ATOM 209 O O . ASN A 1 32 ? -76.594 -12.223 43.182 1.00 60.29 ? 59 ASN A O 1 ATOM 210 C CB . ASN A 1 32 ? -77.299 -9.509 43.991 1.00 78.56 ? 59 ASN A CB 1 ATOM 211 C CG . ASN A 1 32 ? -76.438 -8.801 45.023 1.00 78.83 ? 59 ASN A CG 1 ATOM 212 O OD1 . ASN A 1 32 ? -75.951 -7.694 44.790 1.00 78.79 ? 59 ASN A OD1 1 ATOM 213 N ND2 . ASN A 1 32 ? -76.255 -9.435 46.176 1.00 81.32 ? 59 ASN A ND2 1 ATOM 214 N N . ALA A 1 33 ? -77.167 -11.574 41.107 1.00 62.70 ? 60 ALA A N 1 ATOM 215 C CA . ALA A 1 33 ? -77.467 -12.932 40.659 1.00 61.79 ? 60 ALA A CA 1 ATOM 216 C C . ALA A 1 33 ? -76.233 -13.822 40.639 1.00 61.94 ? 60 ALA A C 1 ATOM 217 O O . ALA A 1 33 ? -75.133 -13.374 40.310 1.00 54.34 ? 60 ALA A O 1 ATOM 218 C CB . ALA A 1 33 ? -78.105 -12.908 39.290 1.00 55.40 ? 60 ALA A CB 1 ATOM 219 N N . GLU A 1 34 ? -76.429 -15.089 40.989 1.00 64.82 ? 61 GLU A N 1 ATOM 220 C CA . GLU A 1 34 ? -75.355 -16.073 40.939 1.00 67.55 ? 61 GLU A CA 1 ATOM 221 C C . GLU A 1 34 ? -75.040 -16.384 39.482 1.00 53.30 ? 61 GLU A C 1 ATOM 222 O O . GLU A 1 34 ? -73.940 -16.109 39.001 1.00 39.82 ? 61 GLU A O 1 ATOM 223 C CB . GLU A 1 34 ? -75.752 -17.353 41.682 1.00 71.08 ? 61 GLU A CB 1 ATOM 224 C CG . GLU A 1 34 ? -76.056 -17.166 43.169 1.00 76.31 ? 61 GLU A CG 1 ATOM 225 C CD . GLU A 1 34 ? -77.458 -16.632 43.435 1.00 77.55 ? 61 GLU A CD 1 ATOM 226 O OE1 . GLU A 1 34 ? -78.294 -16.645 42.506 1.00 66.32 ? 61 GLU A OE1 1 ATOM 227 O OE2 . GLU A 1 34 ? -77.722 -16.199 44.579 1.00 78.72 1 61 GLU A OE2 1 ATOM 228 N N . ASN A 1 35 ? -76.018 -16.964 38.791 1.00 50.52 ? 62 ASN A N 1 ATOM 229 C CA . ASN A 1 35 ? -75.942 -17.170 37.352 1.00 44.83 ? 62 ASN A CA 1 ATOM 230 C C . ASN A 1 35 ? -76.746 -16.079 36.666 1.00 42.87 ? 62 ASN A C 1 ATOM 231 O O . ASN A 1 35 ? -77.951 -16.228 36.467 1.00 46.29 ? 62 ASN A O 1 ATOM 232 C CB . ASN A 1 35 ? -76.500 -18.542 36.977 1.00 46.70 ? 62 ASN A CB 1 ATOM 233 C CG . ASN A 1 35 ? -75.780 -19.677 37.682 1.00 50.36 ? 62 ASN A CG 1 ATOM 234 O OD1 . ASN A 1 35 ? -76.344 -20.334 38.559 1.00 50.72 ? 62 ASN A OD1 1 ATOM 235 N ND2 . ASN A 1 35 ? -74.529 -19.918 37.297 1.00 45.87 ? 62 ASN A ND2 1 ATOM 236 N N . PRO A 1 36 ? -76.079 -14.978 36.294 1.00 38.50 ? 63 PRO A N 1 ATOM 237 C CA . PRO A 1 36 ? -76.796 -13.774 35.877 1.00 37.49 ? 63 PRO A CA 1 ATOM 238 C C . PRO A 1 36 ? -77.509 -13.985 34.557 1.00 32.50 ? 63 PRO A C 1 ATOM 239 O O . PRO A 1 36 ? -77.104 -14.837 33.765 1.00 30.46 ? 63 PRO A O 1 ATOM 240 C CB . PRO A 1 36 ? -75.682 -12.728 35.710 1.00 30.09 ? 63 PRO A CB 1 ATOM 241 C CG . PRO A 1 36 ? -74.390 -13.435 35.975 1.00 26.45 ? 63 PRO A CG 1 ATOM 242 C CD . PRO A 1 36 ? -74.653 -14.903 35.953 1.00 31.68 ? 63 PRO A CD 1 ATOM 243 N N . THR A 1 37 ? -78.571 -13.222 34.339 1.00 28.59 ? 64 THR A N 1 ATOM 244 C CA . THR A 1 37 ? -79.271 -13.249 33.069 1.00 30.76 ? 64 THR A CA 1 ATOM 245 C C . THR A 1 37 ? -78.307 -12.830 31.961 1.00 29.44 ? 64 THR A C 1 ATOM 246 O O . THR A 1 37 ? -78.120 -13.551 30.979 1.00 27.58 ? 64 THR A O 1 ATOM 247 C CB . THR A 1 37 ? -80.488 -12.310 33.086 1.00 29.40 ? 64 THR A CB 1 ATOM 248 O OG1 . THR A 1 37 ? -81.286 -12.582 34.243 1.00 31.18 ? 64 THR A OG1 1 ATOM 249 C CG2 . THR A 1 37 ? -81.333 -12.516 31.854 1.00 28.28 ? 64 THR A CG2 1 ATOM 250 N N . PHE A 1 38 ? -77.678 -11.672 32.143 1.00 26.12 ? 65 PHE A N 1 ATOM 251 C CA . PHE A 1 38 ? -76.746 -11.142 31.157 1.00 21.82 ? 65 PHE A CA 1 ATOM 252 C C . PHE A 1 38 ? -75.389 -10.853 31.764 1.00 21.99 ? 65 PHE A C 1 ATOM 253 O O . PHE A 1 38 ? -75.278 -10.580 32.957 1.00 28.52 ? 65 PHE A O 1 ATOM 254 C CB . PHE A 1 38 ? -77.299 -9.860 30.541 1.00 19.24 ? 65 PHE A CB 1 ATOM 255 C CG . PHE A 1 38 ? -78.585 -10.055 29.812 1.00 22.00 ? 65 PHE A CG 1 ATOM 256 C CD1 . PHE A 1 38 ? -78.601 -10.641 28.561 1.00 21.50 ? 65 PHE A CD1 1 ATOM 257 C CD2 . PHE A 1 38 ? -79.783 -9.658 30.378 1.00 27.82 ? 65 PHE A CD2 1 ATOM 258 C CE1 . PHE A 1 38 ? -79.787 -10.827 27.885 1.00 25.10 ? 65 PHE A CE1 1 ATOM 259 C CE2 . PHE A 1 38 ? -80.974 -9.837 29.706 1.00 27.89 ? 65 PHE A CE2 1 ATOM 260 C CZ . PHE A 1 38 ? -80.976 -10.424 28.458 1.00 26.89 ? 65 PHE A CZ 1 ATOM 261 N N . ARG A 1 39 ? -74.354 -10.904 30.935 1.00 16.32 ? 66 ARG A N 1 ATOM 262 C CA . ARG A 1 39 ? -73.030 -10.499 31.372 1.00 16.95 ? 66 ARG A CA 1 ATOM 263 C C . ARG A 1 39 ? -72.308 -9.764 30.256 1.00 18.01 ? 66 ARG A C 1 ATOM 264 O O . ARG A 1 39 ? -71.443 -10.325 29.588 1.00 21.08 ? 66 ARG A O 1 ATOM 265 C CB . ARG A 1 39 ? -72.212 -11.702 31.826 1.00 21.63 ? 66 ARG A CB 1 ATOM 266 C CG . ARG A 1 39 ? -71.018 -11.326 32.683 1.00 26.05 ? 66 ARG A CG 1 ATOM 267 C CD . ARG A 1 39 ? -70.045 -12.479 32.809 1.00 31.63 ? 66 ARG A CD 1 ATOM 268 N NE . ARG A 1 39 ? -70.694 -13.708 33.250 1.00 33.89 ? 66 ARG A NE 1 ATOM 269 C CZ . ARG A 1 39 ? -70.967 -13.992 34.519 1.00 32.52 ? 66 ARG A CZ 1 ATOM 270 N NH1 . ARG A 1 39 ? -70.657 -13.127 35.476 1.00 30.97 1 66 ARG A NH1 1 ATOM 271 N NH2 . ARG A 1 39 ? -71.553 -15.141 34.828 1.00 29.46 ? 66 ARG A NH2 1 ATOM 272 N N . LEU A 1 40 ? -72.674 -8.505 30.060 1.00 18.67 ? 67 LEU A N 1 ATOM 273 C CA . LEU A 1 40 ? -72.058 -7.673 29.039 1.00 17.50 ? 67 LEU A CA 1 ATOM 274 C C . LEU A 1 40 ? -70.605 -7.437 29.384 1.00 19.30 ? 67 LEU A C 1 ATOM 275 O O . LEU A 1 40 ? -70.260 -7.281 30.552 1.00 22.85 ? 67 LEU A O 1 ATOM 276 C CB . LEU A 1 40 ? -72.759 -6.321 28.939 1.00 16.39 ? 67 LEU A CB 1 ATOM 277 C CG . LEU A 1 40 ? -74.140 -6.216 28.301 1.00 16.07 ? 67 LEU A CG 1 ATOM 278 C CD1 . LEU A 1 40 ? -75.203 -6.955 29.099 1.00 15.34 ? 67 LEU A CD1 1 ATOM 279 C CD2 . LEU A 1 40 ? -74.497 -4.751 28.183 1.00 22.16 ? 67 LEU A CD2 1 ATOM 280 N N . THR A 1 41 ? -69.760 -7.414 28.362 1.00 18.82 ? 68 THR A N 1 ATOM 281 C CA . THR A 1 41 ? -68.354 -7.095 28.535 1.00 20.63 ? 68 THR A CA 1 ATOM 282 C C . THR A 1 41 ? -67.970 -6.052 27.496 1.00 22.99 ? 68 THR A C 1 ATOM 283 O O . THR A 1 41 ? -67.806 -6.364 26.316 1.00 24.24 ? 68 THR A O 1 ATOM 284 C CB . THR A 1 41 ? -67.468 -8.346 28.392 1.00 21.23 ? 68 THR A CB 1 ATOM 285 O OG1 . THR A 1 41 ? -67.800 -9.288 29.420 1.00 17.89 ? 68 THR A OG1 1 ATOM 286 C CG2 . THR A 1 41 ? -66.002 -7.979 28.511 1.00 29.94 ? 68 THR A CG2 1 ATOM 287 N N . ILE A 1 42 ? -67.846 -4.804 27.931 1.00 25.72 ? 69 ILE A N 1 ATOM 288 C CA . ILE A 1 42 ? -67.600 -3.713 26.996 1.00 29.16 ? 69 ILE A CA 1 ATOM 289 C C . ILE A 1 42 ? -66.146 -3.248 26.996 1.00 29.74 ? 69 ILE A C 1 ATOM 290 O O . ILE A 1 42 ? -65.576 -2.942 28.039 1.00 34.05 ? 69 ILE A O 1 ATOM 291 C CB . ILE A 1 42 ? -68.523 -2.494 27.263 1.00 24.27 ? 69 ILE A CB 1 ATOM 292 C CG1 . ILE A 1 42 ? -69.996 -2.890 27.170 1.00 24.12 ? 69 ILE A CG1 1 ATOM 293 C CG2 . ILE A 1 42 ? -68.230 -1.377 26.285 1.00 22.11 ? 69 ILE A CG2 1 ATOM 294 C CD1 . ILE A 1 42 ? -70.631 -3.237 28.500 1.00 25.81 ? 69 ILE A CD1 1 ATOM 295 N N . GLN A 1 43 ? -65.554 -3.217 25.810 1.00 29.58 ? 70 GLN A N 1 ATOM 296 C CA . GLN A 1 43 ? -64.280 -2.556 25.587 1.00 29.44 ? 70 GLN A CA 1 ATOM 297 C C . GLN A 1 43 ? -64.535 -1.465 24.545 1.00 30.55 ? 70 GLN A C 1 ATOM 298 O O . GLN A 1 43 ? -64.528 -1.732 23.338 1.00 26.60 ? 70 GLN A O 1 ATOM 299 C CB . GLN A 1 43 ? -63.226 -3.564 25.119 1.00 31.96 ? 70 GLN A CB 1 ATOM 300 C CG . GLN A 1 43 ? -61.956 -2.964 24.515 1.00 42.88 ? 70 GLN A CG 1 ATOM 301 C CD . GLN A 1 43 ? -60.929 -2.548 25.553 1.00 48.23 ? 70 GLN A CD 1 ATOM 302 O OE1 . GLN A 1 43 ? -61.275 -2.040 26.620 1.00 52.70 ? 70 GLN A OE1 1 ATOM 303 N NE2 . GLN A 1 43 ? -59.653 -2.765 25.241 1.00 40.10 ? 70 GLN A NE2 1 ATOM 304 N N . PRO A 1 44 ? -64.804 -0.237 25.022 1.00 33.30 ? 71 PRO A N 1 ATOM 305 C CA . PRO A 1 44 ? -65.218 0.948 24.254 1.00 33.81 ? 71 PRO A CA 1 ATOM 306 C C . PRO A 1 44 ? -64.454 1.136 22.950 1.00 32.70 ? 71 PRO A C 1 ATOM 307 O O . PRO A 1 44 ? -63.285 0.774 22.881 1.00 41.76 ? 71 PRO A O 1 ATOM 308 C CB . PRO A 1 44 ? -64.915 2.095 25.214 1.00 33.62 ? 71 PRO A CB 1 ATOM 309 C CG . PRO A 1 44 ? -65.157 1.497 26.560 1.00 35.44 ? 71 PRO A CG 1 ATOM 310 C CD . PRO A 1 44 ? -64.725 0.055 26.466 1.00 31.81 ? 71 PRO A CD 1 ATOM 311 N N . LYS A 1 45 ? -65.124 1.681 21.936 1.00 31.17 ? 72 LYS A N 1 ATOM 312 C CA . LYS A 1 45 ? -64.568 1.844 20.589 1.00 26.97 ? 72 LYS A CA 1 ATOM 313 C C . LYS A 1 45 ? -64.278 0.526 19.866 1.00 28.81 ? 72 LYS A C 1 ATOM 314 O O . LYS A 1 45 ? -64.366 0.456 18.641 1.00 35.40 ? 72 LYS A O 1 ATOM 315 C CB . LYS A 1 45 ? -63.327 2.743 20.589 1.00 26.40 ? 72 LYS A CB 1 ATOM 316 C CG . LYS A 1 45 ? -63.618 4.233 20.704 1.00 35.29 ? 72 LYS A CG 1 ATOM 317 C CD . LYS A 1 45 ? -62.321 5.050 20.641 1.00 60.03 ? 72 LYS A CD 1 ATOM 318 C CE . LYS A 1 45 ? -62.571 6.556 20.757 1.00 54.43 ? 72 LYS A CE 1 ATOM 319 N NZ . LYS A 1 45 ? -61.302 7.340 20.871 1.00 27.45 1 72 LYS A NZ 1 ATOM 320 N N . ASP A 1 46 ? -63.949 -0.517 20.620 1.00 26.94 ? 73 ASP A N 1 ATOM 321 C CA . ASP A 1 46 ? -63.592 -1.799 20.023 1.00 35.73 ? 73 ASP A CA 1 ATOM 322 C C . ASP A 1 46 ? -64.806 -2.707 19.836 1.00 34.40 ? 73 ASP A C 1 ATOM 323 O O . ASP A 1 46 ? -65.482 -2.650 18.803 1.00 31.83 ? 73 ASP A O 1 ATOM 324 C CB . ASP A 1 46 ? -62.519 -2.504 20.859 1.00 41.88 ? 73 ASP A CB 1 ATOM 325 C CG . ASP A 1 46 ? -61.850 -3.648 20.113 1.00 51.16 ? 73 ASP A CG 1 ATOM 326 O OD1 . ASP A 1 46 ? -62.151 -3.843 18.913 1.00 49.50 ? 73 ASP A OD1 1 ATOM 327 O OD2 . ASP A 1 46 ? -61.007 -4.343 20.725 1.00 53.11 1 73 ASP A OD2 1 ATOM 328 N N . TYR A 1 47 ? -65.079 -3.541 20.835 1.00 26.66 ? 74 TYR A N 1 ATOM 329 C CA . TYR A 1 47 ? -66.129 -4.540 20.710 1.00 25.38 ? 74 TYR A CA 1 ATOM 330 C C . TYR A 1 47 ? -67.083 -4.532 21.907 1.00 19.84 ? 74 TYR A C 1 ATOM 331 O O . TYR A 1 47 ? -66.987 -3.673 22.780 1.00 19.20 ? 74 TYR A O 1 ATOM 332 C CB . TYR A 1 47 ? -65.509 -5.930 20.522 1.00 28.08 ? 74 TYR A CB 1 ATOM 333 C CG . TYR A 1 47 ? -64.913 -6.503 21.785 1.00 30.21 ? 74 TYR A CG 1 ATOM 334 C CD1 . TYR A 1 47 ? -63.693 -6.053 22.263 1.00 31.93 ? 74 TYR A CD1 1 ATOM 335 C CD2 . TYR A 1 47 ? -65.578 -7.492 22.505 1.00 28.44 ? 74 TYR A CD2 1 ATOM 336 C CE1 . TYR A 1 47 ? -63.148 -6.570 23.425 1.00 39.42 ? 74 TYR A CE1 1 ATOM 337 C CE2 . TYR A 1 47 ? -65.043 -8.015 23.668 1.00 28.30 ? 74 TYR A CE2 1 ATOM 338 C CZ . TYR A 1 47 ? -63.827 -7.549 24.124 1.00 39.77 ? 74 TYR A CZ 1 ATOM 339 O OH . TYR A 1 47 ? -63.279 -8.061 25.279 1.00 51.24 ? 74 TYR A OH 1 ATOM 340 N N . VAL A 1 48 ? -68.012 -5.483 21.922 1.00 16.48 ? 75 VAL A N 1 ATOM 341 C CA . VAL A 1 48 ? -68.897 -5.698 23.064 1.00 16.09 ? 75 VAL A CA 1 ATOM 342 C C . VAL A 1 48 ? -69.516 -7.087 23.009 1.00 11.46 ? 75 VAL A C 1 ATOM 343 O O . VAL A 1 48 ? -70.225 -7.424 22.069 1.00 8.59 ? 75 VAL A O 1 ATOM 344 C CB . VAL A 1 48 ? -70.015 -4.634 23.149 1.00 17.55 ? 75 VAL A CB 1 ATOM 345 C CG1 . VAL A 1 48 ? -70.516 -4.270 21.767 1.00 15.86 ? 75 VAL A CG1 1 ATOM 346 C CG2 . VAL A 1 48 ? -71.154 -5.118 24.038 1.00 12.50 ? 75 VAL A CG2 1 ATOM 347 N N . GLN A 1 49 ? -69.232 -7.898 24.019 1.00 12.43 ? 76 GLN A N 1 ATOM 348 C CA . GLN A 1 49 ? -69.769 -9.249 24.073 1.00 12.10 ? 76 GLN A CA 1 ATOM 349 C C . GLN A 1 49 ? -70.948 -9.342 25.020 1.00 12.32 ? 76 GLN A C 1 ATOM 350 O O . GLN A 1 49 ? -70.854 -8.934 26.176 1.00 14.57 ? 76 GLN A O 1 ATOM 351 C CB . GLN A 1 49 ? -68.700 -10.251 24.501 1.00 13.78 ? 76 GLN A CB 1 ATOM 352 C CG . GLN A 1 49 ? -69.275 -11.449 25.244 1.00 14.53 ? 76 GLN A CG 1 ATOM 353 C CD . GLN A 1 49 ? -68.360 -12.648 25.222 1.00 19.39 ? 76 GLN A CD 1 ATOM 354 O OE1 . GLN A 1 49 ? -67.349 -12.658 24.517 1.00 17.65 ? 76 GLN A OE1 1 ATOM 355 N NE2 . GLN A 1 49 ? -68.710 -13.675 25.992 1.00 17.57 ? 76 GLN A NE2 1 ATOM 356 N N . ILE A 1 50 ? -72.051 -9.897 24.524 1.00 11.25 ? 77 ILE A N 1 ATOM 357 C CA . ILE A 1 50 ? -73.261 -10.063 25.320 1.00 11.13 ? 77 ILE A CA 1 ATOM 358 C C . ILE A 1 50 ? -73.551 -11.536 25.602 1.00 10.60 ? 77 ILE A C 1 ATOM 359 O O . ILE A 1 50 ? -73.999 -12.270 24.726 1.00 9.30 ? 77 ILE A O 1 ATOM 360 C CB . ILE A 1 50 ? -74.464 -9.441 24.618 1.00 9.77 ? 77 ILE A CB 1 ATOM 361 C CG1 . ILE A 1 50 ? -74.150 -8.001 24.221 1.00 9.38 ? 77 ILE A CG1 1 ATOM 362 C CG2 . ILE A 1 50 ? -75.690 -9.496 25.512 1.00 13.18 ? 77 ILE A CG2 1 ATOM 363 C CD1 . ILE A 1 50 ? -75.276 -7.323 23.471 1.00 9.63 ? 77 ILE A CD1 1 ATOM 364 N N . MET A 1 51 ? -73.294 -11.955 26.835 1.00 12.69 ? 78 MET A N 1 ATOM 365 C CA . MET A 1 51 ? -73.409 -13.356 27.216 1.00 13.50 ? 78 MET A CA 1 ATOM 366 C C . MET A 1 51 ? -74.687 -13.571 27.995 1.00 14.61 ? 78 MET A C 1 ATOM 367 O O . MET A 1 51 ? -74.825 -13.092 29.120 1.00 19.50 ? 78 MET A O 1 ATOM 368 C CB . MET A 1 51 ? -72.203 -13.774 28.060 1.00 18.43 ? 78 MET A CB 1 ATOM 369 C CG . MET A 1 51 ? -72.397 -15.059 28.856 1.00 23.25 ? 78 MET A CG 1 ATOM 370 S SD . MET A 1 51 ? -71.948 -16.539 27.939 1.00 32.58 ? 78 MET A SD 1 ATOM 371 C CE . MET A 1 51 ? -70.267 -16.131 27.490 1.00 29.47 ? 78 MET A CE 1 ATOM 372 N N . CYS A 1 52 ? -75.618 -14.303 27.395 1.00 13.14 ? 79 CYS A N 1 ATOM 373 C CA . CYS A 1 52 ? -76.943 -14.470 27.965 1.00 12.78 ? 79 CYS A CA 1 ATOM 374 C C . CYS A 1 52 ? -77.091 -15.776 28.735 1.00 14.54 ? 79 CYS A C 1 ATOM 375 O O . CYS A 1 52 ? -76.260 -16.672 28.637 1.00 17.08 ? 79 CYS A O 1 ATOM 376 C CB . CYS A 1 52 ? -77.991 -14.414 26.854 1.00 14.46 ? 79 CYS A CB 1 ATOM 377 S SG . CYS A 1 52 ? -77.854 -12.990 25.752 1.00 17.11 ? 79 CYS A SG 1 ATOM 378 N N . ASN A 1 53 ? -78.166 -15.869 29.505 1.00 16.05 ? 80 ASN A N 1 ATOM 379 C CA . ASN A 1 53 ? -78.543 -17.102 30.170 1.00 18.51 ? 80 ASN A CA 1 ATOM 380 C C . ASN A 1 53 ? -80.056 -17.057 30.366 1.00 21.77 ? 80 ASN A C 1 ATOM 381 O O . ASN A 1 53 ? -80.546 -16.712 31.441 1.00 25.61 ? 80 ASN A O 1 ATOM 382 C CB . ASN A 1 53 ? -77.806 -17.225 31.501 1.00 24.06 ? 80 ASN A CB 1 ATOM 383 C CG . ASN A 1 53 ? -77.840 -18.630 32.064 1.00 24.57 ? 80 ASN A CG 1 ATOM 384 O OD1 . ASN A 1 53 ? -78.334 -19.558 31.424 1.00 23.10 ? 80 ASN A OD1 1 ATOM 385 N ND2 . ASN A 1 53 ? -77.302 -18.793 33.270 1.00 28.21 ? 80 ASN A ND2 1 ATOM 386 N N . LEU A 1 54 ? -80.792 -17.387 29.307 1.00 23.16 ? 81 LEU A N 1 ATOM 387 C CA . LEU A 1 54 ? -82.224 -17.085 29.234 1.00 23.30 ? 81 LEU A CA 1 ATOM 388 C C . LEU A 1 54 ? -83.121 -18.328 29.172 1.00 22.27 ? 81 LEU A C 1 ATOM 389 O O . LEU A 1 54 ? -82.741 -19.356 28.611 1.00 20.64 ? 81 LEU A O 1 ATOM 390 C CB . LEU A 1 54 ? -82.503 -16.180 28.025 1.00 20.96 ? 81 LEU A CB 1 ATOM 391 C CG . LEU A 1 54 ? -82.268 -14.663 28.076 1.00 21.37 ? 81 LEU A CG 1 ATOM 392 C CD1 . LEU A 1 54 ? -81.026 -14.287 28.849 1.00 24.39 ? 81 LEU A CD1 1 ATOM 393 C CD2 . LEU A 1 54 ? -82.174 -14.082 26.674 1.00 17.01 ? 81 LEU A CD2 1 ATOM 394 N N . THR A 1 55 ? -84.315 -18.218 29.751 1.00 22.07 ? 82 THR A N 1 ATOM 395 C CA . THR A 1 55 ? -85.302 -19.296 29.729 1.00 27.87 ? 82 THR A CA 1 ATOM 396 C C . THR A 1 55 ? -86.366 -19.033 28.670 1.00 33.82 ? 82 THR A C 1 ATOM 397 O O . THR A 1 55 ? -86.471 -19.759 27.682 1.00 38.47 ? 82 THR A O 1 ATOM 398 C CB . THR A 1 55 ? -86.011 -19.426 31.077 1.00 26.88 ? 82 THR A CB 1 ATOM 399 O OG1 . THR A 1 55 ? -86.774 -18.240 31.325 1.00 29.54 ? 82 THR A OG1 1 ATOM 400 C CG2 . THR A 1 55 ? -84.998 -19.612 32.189 1.00 31.39 ? 82 THR A CG2 1 ATOM 401 N N . ASP A 1 56 ? -87.171 -18.000 28.899 1.00 34.34 ? 83 ASP A N 1 ATOM 402 C CA . ASP A 1 56 ? -88.096 -17.509 27.888 1.00 38.04 ? 83 ASP A CA 1 ATOM 403 C C . ASP A 1 56 ? -87.540 -16.213 27.309 1.00 34.87 ? 83 ASP A C 1 ATOM 404 O O . ASP A 1 56 ? -86.648 -15.606 27.887 1.00 32.63 ? 83 ASP A O 1 ATOM 405 C CB . ASP A 1 56 ? -89.493 -17.289 28.479 1.00 40.76 ? 83 ASP A CB 1 ATOM 406 C CG . ASP A 1 56 ? -90.207 -18.598 28.802 1.00 47.92 ? 83 ASP A CG 1 ATOM 407 O OD1 . ASP A 1 56 ? -90.806 -19.193 27.877 1.00 43.75 ? 83 ASP A OD1 1 ATOM 408 O OD2 . ASP A 1 56 ? -90.175 -19.029 29.979 1.00 42.97 1 83 ASP A OD2 1 ATOM 409 N N . THR A 1 57 ? -88.068 -15.789 26.169 1.00 41.56 ? 84 THR A N 1 ATOM 410 C CA . THR A 1 57 ? -87.557 -14.606 25.479 1.00 40.27 ? 84 THR A CA 1 ATOM 411 C C . THR A 1 57 ? -87.817 -13.308 26.254 1.00 34.67 ? 84 THR A C 1 ATOM 412 O O . THR A 1 57 ? -87.276 -12.254 25.918 1.00 25.34 ? 84 THR A O 1 ATOM 413 C CB . THR A 1 57 ? -88.173 -14.487 24.061 1.00 46.95 ? 84 THR A CB 1 ATOM 414 O OG1 . THR A 1 57 ? -87.432 -13.540 23.279 1.00 34.08 ? 84 THR A OG1 1 ATOM 415 C CG2 . THR A 1 57 ? -89.642 -14.063 24.143 1.00 41.45 ? 84 THR A CG2 1 ATOM 416 N N . THR A 1 58 ? -88.640 -13.397 27.294 1.00 42.94 ? 85 THR A N 1 ATOM 417 C CA . THR A 1 58 ? -89.099 -12.217 28.028 1.00 46.90 ? 85 THR A CA 1 ATOM 418 C C . THR A 1 58 ? -88.076 -11.691 29.033 1.00 42.85 ? 85 THR A C 1 ATOM 419 O O . THR A 1 58 ? -88.342 -10.730 29.758 1.00 41.76 ? 85 THR A O 1 ATOM 420 C CB . THR A 1 58 ? -90.424 -12.500 28.771 1.00 40.57 ? 85 THR A CB 1 ATOM 421 O OG1 . THR A 1 58 ? -90.241 -13.595 29.676 1.00 41.43 ? 85 THR A OG1 1 ATOM 422 C CG2 . THR A 1 58 ? -91.525 -12.846 27.781 1.00 41.33 ? 85 THR A CG2 1 ATOM 423 N N . ASP A 1 59 ? -86.907 -12.322 29.068 1.00 39.97 ? 86 ASP A N 1 ATOM 424 C CA . ASP A 1 59 ? -85.875 -11.966 30.033 1.00 31.11 ? 86 ASP A CA 1 ATOM 425 C C . ASP A 1 59 ? -85.102 -10.728 29.607 1.00 31.32 ? 86 ASP A C 1 ATOM 426 O O . ASP A 1 59 ? -84.370 -10.145 30.402 1.00 38.79 ? 86 ASP A O 1 ATOM 427 C CB . ASP A 1 59 ? -84.913 -13.134 30.234 1.00 22.64 ? 86 ASP A CB 1 ATOM 428 C CG . ASP A 1 59 ? -85.635 -14.433 30.513 1.00 31.30 ? 86 ASP A CG 1 ATOM 429 O OD1 . ASP A 1 59 ? -86.773 -14.388 31.030 1.00 35.53 ? 86 ASP A OD1 1 ATOM 430 O OD2 . ASP A 1 59 ? -85.067 -15.502 30.207 1.00 31.32 1 86 ASP A OD2 1 ATOM 431 N N . TYR A 1 60 ? -85.276 -10.315 28.358 1.00 30.82 ? 87 TYR A N 1 ATOM 432 C CA . TYR A 1 60 ? -84.532 -9.177 27.825 1.00 30.52 ? 87 TYR A CA 1 ATOM 433 C C . TYR A 1 60 ? -84.855 -7.857 28.524 1.00 34.59 ? 87 TYR A C 1 ATOM 434 O O . TYR A 1 60 ? -84.240 -6.832 28.231 1.00 33.65 ? 87 TYR A O 1 ATOM 435 C CB . TYR A 1 60 ? -84.764 -9.038 26.322 1.00 29.54 ? 87 TYR A CB 1 ATOM 436 C CG . TYR A 1 60 ? -83.974 -10.011 25.477 1.00 29.76 ? 87 TYR A CG 1 ATOM 437 C CD1 . TYR A 1 60 ? -82.661 -9.743 25.113 1.00 26.44 ? 87 TYR A CD1 1 ATOM 438 C CD2 . TYR A 1 60 ? -84.545 -11.191 25.029 1.00 36.34 ? 87 TYR A CD2 1 ATOM 439 C CE1 . TYR A 1 60 ? -81.938 -10.631 24.330 1.00 21.08 ? 87 TYR A CE1 1 ATOM 440 C CE2 . TYR A 1 60 ? -83.828 -12.084 24.245 1.00 31.07 ? 87 TYR A CE2 1 ATOM 441 C CZ . TYR A 1 60 ? -82.528 -11.799 23.901 1.00 18.99 ? 87 TYR A CZ 1 ATOM 442 O OH . TYR A 1 60 ? -81.825 -12.690 23.124 1.00 13.14 ? 87 TYR A OH 1 ATOM 443 N N . GLN A 1 61 ? -85.820 -7.885 29.439 1.00 40.81 ? 88 GLN A N 1 ATOM 444 C CA . GLN A 1 61 ? -86.182 -6.706 30.221 1.00 44.97 ? 88 GLN A CA 1 ATOM 445 C C . GLN A 1 61 ? -85.066 -6.332 31.186 1.00 36.31 ? 88 GLN A C 1 ATOM 446 O O . GLN A 1 61 ? -84.814 -5.151 31.442 1.00 28.33 ? 88 GLN A O 1 ATOM 447 C CB . GLN A 1 61 ? -87.469 -6.958 31.008 1.00 44.72 ? 88 GLN A CB 1 ATOM 448 C CG . GLN A 1 61 ? -88.732 -7.015 30.165 1.00 47.15 ? 88 GLN A CG 1 ATOM 449 C CD . GLN A 1 61 ? -89.975 -7.179 31.015 1.00 51.17 ? 88 GLN A CD 1 ATOM 450 O OE1 . GLN A 1 61 ? -89.992 -7.973 31.956 1.00 55.48 ? 88 GLN A OE1 1 ATOM 451 N NE2 . GLN A 1 61 ? -91.019 -6.416 30.699 1.00 45.12 ? 88 GLN A NE2 1 ATOM 452 N N . GLN A 1 62 ? -84.393 -7.353 31.707 1.00 31.96 ? 89 GLN A N 1 ATOM 453 C CA . GLN A 1 62 ? -83.373 -7.168 32.730 1.00 38.14 ? 89 GLN A CA 1 ATOM 454 C C . GLN A 1 62 ? -82.064 -6.643 32.154 1.00 36.61 ? 89 GLN A C 1 ATOM 455 O O . GLN A 1 62 ? -81.066 -6.510 32.869 1.00 36.55 ? 89 GLN A O 1 ATOM 456 C CB . GLN A 1 62 ? -83.154 -8.473 33.493 1.00 36.83 ? 89 GLN A CB 1 ATOM 457 C CG . GLN A 1 62 ? -84.421 -8.968 34.172 1.00 37.36 ? 89 GLN A CG 1 ATOM 458 C CD . GLN A 1 62 ? -84.591 -10.466 34.066 1.00 36.87 ? 89 GLN A CD 1 ATOM 459 O OE1 . GLN A 1 62 ? -83.619 -11.220 34.152 1.00 35.21 ? 89 GLN A OE1 1 ATOM 460 N NE2 . GLN A 1 62 ? -85.832 -10.909 33.871 1.00 29.67 ? 89 GLN A NE2 1 ATOM 461 N N . LEU A 1 63 ? -82.085 -6.342 30.859 1.00 29.71 ? 90 LEU A N 1 ATOM 462 C CA . LEU A 1 63 ? -80.969 -5.692 30.189 1.00 30.65 ? 90 LEU A CA 1 ATOM 463 C C . LEU A 1 63 ? -80.740 -4.326 30.828 1.00 31.85 ? 90 LEU A C 1 ATOM 464 O O . LEU A 1 63 ? -81.681 -3.706 31.318 1.00 39.18 ? 90 LEU A O 1 ATOM 465 C CB . LEU A 1 63 ? -81.290 -5.533 28.703 1.00 31.59 ? 90 LEU A CB 1 ATOM 466 C CG . LEU A 1 63 ? -80.188 -5.785 27.670 1.00 30.37 ? 90 LEU A CG 1 ATOM 467 C CD1 . LEU A 1 63 ? -79.597 -7.176 27.816 1.00 21.87 ? 90 LEU A CD1 1 ATOM 468 C CD2 . LEU A 1 63 ? -80.739 -5.594 26.271 1.00 32.76 ? 90 LEU A CD2 1 ATOM 469 N N . PRO A 1 64 ? -79.486 -3.853 30.841 1.00 31.18 ? 91 PRO A N 1 ATOM 470 C CA . PRO A 1 64 ? -79.242 -2.538 31.440 1.00 41.98 ? 91 PRO A CA 1 ATOM 471 C C . PRO A 1 64 ? -79.888 -1.414 30.626 1.00 43.14 ? 91 PRO A C 1 ATOM 472 O O . PRO A 1 64 ? -79.747 -1.365 29.399 1.00 38.16 ? 91 PRO A O 1 ATOM 473 C CB . PRO A 1 64 ? -77.711 -2.421 31.422 1.00 38.93 ? 91 PRO A CB 1 ATOM 474 C CG . PRO A 1 64 ? -77.270 -3.344 30.338 1.00 28.62 ? 91 PRO A CG 1 ATOM 475 C CD . PRO A 1 64 ? -78.242 -4.485 30.369 1.00 31.71 ? 91 PRO A CD 1 ATOM 476 N N . LYS A 1 65 ? -80.591 -0.522 31.316 1.00 38.11 ? 92 LYS A N 1 ATOM 477 C CA . LYS A 1 65 ? -81.305 0.568 30.662 1.00 40.52 ? 92 LYS A CA 1 ATOM 478 C C . LYS A 1 65 ? -80.406 1.776 30.410 1.00 43.18 ? 92 LYS A C 1 ATOM 479 O O . LYS A 1 65 ? -79.545 2.093 31.229 1.00 47.49 ? 92 LYS A O 1 ATOM 480 C CB . LYS A 1 65 ? -82.498 0.987 31.520 1.00 46.41 ? 92 LYS A CB 1 ATOM 481 C CG . LYS A 1 65 ? -83.198 -0.177 32.204 1.00 48.96 ? 92 LYS A CG 1 ATOM 482 C CD . LYS A 1 65 ? -84.495 0.265 32.864 1.00 45.12 ? 92 LYS A CD 1 ATOM 483 C CE . LYS A 1 65 ? -85.238 -0.916 33.468 1.00 37.15 ? 92 LYS A CE 1 ATOM 484 N NZ . LYS A 1 65 ? -86.534 -0.510 34.073 1.00 34.51 1 92 LYS A NZ 1 ATOM 485 N N . LYS A 1 66 ? -80.618 2.444 29.279 1.00 45.30 ? 93 LYS A N 1 ATOM 486 C CA . LYS A 1 66 ? -79.908 3.681 28.943 1.00 48.88 ? 93 LYS A CA 1 ATOM 487 C C . LYS A 1 66 ? -78.395 3.547 29.042 1.00 43.03 ? 93 LYS A C 1 ATOM 488 O O . LYS A 1 66 ? -77.754 4.324 29.749 1.00 41.59 ? 93 LYS A O 1 ATOM 489 C CB . LYS A 1 66 ? -80.353 4.831 29.854 1.00 53.65 ? 93 LYS A CB 1 ATOM 490 C CG . LYS A 1 66 ? -81.802 5.269 29.701 1.00 59.34 ? 93 LYS A CG 1 ATOM 491 C CD . LYS A 1 66 ? -82.084 6.476 30.594 1.00 66.08 ? 93 LYS A CD 1 ATOM 492 C CE . LYS A 1 66 ? -83.522 6.971 30.470 1.00 71.22 ? 93 LYS A CE 1 ATOM 493 N NZ . LYS A 1 66 ? -84.513 6.093 31.161 1.00 66.26 1 93 LYS A NZ 1 ATOM 494 N N . LEU A 1 67 ? -77.822 2.578 28.334 1.00 41.21 ? 94 LEU A N 1 ATOM 495 C CA . LEU A 1 67 ? -76.400 2.281 28.494 1.00 39.46 ? 94 LEU A CA 1 ATOM 496 C C . LEU A 1 67 ? -75.459 3.184 27.692 1.00 36.29 ? 94 LEU A C 1 ATOM 497 O O . LEU A 1 67 ? -74.439 3.636 28.216 1.00 39.02 ? 94 LEU A O 1 ATOM 498 C CB . LEU A 1 67 ? -76.109 0.815 28.182 1.00 35.18 ? 94 LEU A CB 1 ATOM 499 C CG . LEU A 1 67 ? -74.882 0.312 28.939 1.00 31.56 ? 94 LEU A CG 1 ATOM 500 C CD1 . LEU A 1 67 ? -75.202 0.230 30.426 1.00 36.75 ? 94 LEU A CD1 1 ATOM 501 C CD2 . LEU A 1 67 ? -74.414 -1.027 28.402 1.00 31.30 ? 94 LEU A CD2 1 ATOM 502 N N . ARG A 1 68 ? -75.796 3.422 26.426 1.00 29.96 ? 95 ARG A N 1 ATOM 503 C CA . ARG A 1 68 ? -75.005 4.289 25.546 1.00 32.31 ? 95 ARG A CA 1 ATOM 504 C C . ARG A 1 68 ? -73.549 3.843 25.352 1.00 29.43 ? 95 ARG A C 1 ATOM 505 O O . ARG A 1 68 ? -72.622 4.482 25.845 1.00 31.81 ? 95 ARG A O 1 ATOM 506 C CB . ARG A 1 68 ? -75.056 5.739 26.032 1.00 34.27 ? 95 ARG A CB 1 ATOM 507 C CG . ARG A 1 68 ? -76.400 6.405 25.832 1.00 34.82 ? 95 ARG A CG 1 ATOM 508 C CD . ARG A 1 68 ? -76.756 6.456 24.354 1.00 43.77 ? 95 ARG A CD 1 ATOM 509 N NE . ARG A 1 68 ? -78.047 7.099 24.112 1.00 55.48 ? 95 ARG A NE 1 ATOM 510 C CZ . ARG A 1 68 ? -79.205 6.452 23.999 1.00 40.80 ? 95 ARG A CZ 1 ATOM 511 N NH1 . ARG A 1 68 ? -79.252 5.130 24.106 1.00 35.36 1 95 ARG A NH1 1 ATOM 512 N NH2 . ARG A 1 68 ? -80.321 7.133 23.778 1.00 34.63 ? 95 ARG A NH2 1 ATOM 513 N N . ILE A 1 69 ? -73.360 2.757 24.614 1.00 26.07 ? 96 ILE A N 1 ATOM 514 C CA . ILE A 1 69 ? -72.034 2.196 24.384 1.00 27.85 ? 96 ILE A CA 1 ATOM 515 C C . ILE A 1 69 ? -71.325 2.905 23.229 1.00 31.84 ? 96 ILE A C 1 ATOM 516 O O . ILE A 1 69 ? -70.113 2.787 23.057 1.00 36.58 ? 96 ILE A O 1 ATOM 517 C CB . ILE A 1 69 ? -72.125 0.678 24.114 1.00 24.47 ? 96 ILE A CB 1 ATOM 518 C CG1 . ILE A 1 69 ? -72.977 0.009 25.193 1.00 23.61 ? 96 ILE A CG1 1 ATOM 519 C CG2 . ILE A 1 69 ? -70.746 0.037 24.056 1.00 19.68 ? 96 ILE A CG2 1 ATOM 520 C CD1 . ILE A 1 69 ? -73.059 -1.491 25.060 1.00 21.24 ? 96 ILE A CD1 1 ATOM 521 N N . GLY A 1 70 ? -72.084 3.660 22.445 1.00 33.77 ? 97 GLY A N 1 ATOM 522 C CA . GLY A 1 70 ? -71.515 4.389 21.326 1.00 35.44 ? 97 GLY A CA 1 ATOM 523 C C . GLY A 1 70 ? -70.962 3.485 20.244 1.00 33.03 ? 97 GLY A C 1 ATOM 524 O O . GLY A 1 70 ? -71.298 2.302 20.182 1.00 31.88 ? 97 GLY A O 1 ATOM 525 N N . GLU A 1 71 ? -70.116 4.045 19.386 1.00 32.77 ? 98 GLU A N 1 ATOM 526 C CA . GLU A 1 71 ? -69.568 3.294 18.263 1.00 35.15 ? 98 GLU A CA 1 ATOM 527 C C . GLU A 1 71 ? -68.776 2.074 18.725 1.00 37.74 ? 98 GLU A C 1 ATOM 528 O O . GLU A 1 71 ? -68.113 2.100 19.766 1.00 29.51 ? 98 GLU A O 1 ATOM 529 C CB . GLU A 1 71 ? -68.717 4.193 17.360 1.00 40.71 ? 98 GLU A CB 1 ATOM 530 C CG . GLU A 1 71 ? -69.512 4.900 16.260 1.00 54.81 ? 98 GLU A CG 1 ATOM 531 C CD . GLU A 1 71 ? -69.661 6.400 16.488 1.00 67.57 ? 98 GLU A CD 1 ATOM 532 O OE1 . GLU A 1 71 ? -68.898 6.964 17.308 1.00 62.19 ? 98 GLU A OE1 1 ATOM 533 O OE2 . GLU A 1 71 ? -70.543 7.012 15.841 1.00 55.91 1 98 GLU A OE2 1 ATOM 534 N N . VAL A 1 72 ? -68.878 0.999 17.950 1.00 38.53 ? 99 VAL A N 1 ATOM 535 C CA . VAL A 1 72 ? -68.206 -0.255 18.260 1.00 32.79 ? 99 VAL A CA 1 ATOM 536 C C . VAL A 1 72 ? -68.029 -1.044 16.967 1.00 30.39 ? 99 VAL A C 1 ATOM 537 O O . VAL A 1 72 ? -68.876 -0.992 16.074 1.00 29.72 ? 99 VAL A O 1 ATOM 538 C CB . VAL A 1 72 ? -68.992 -1.073 19.320 1.00 25.96 ? 99 VAL A CB 1 ATOM 539 C CG1 . VAL A 1 72 ? -69.689 -2.269 18.695 1.00 23.10 ? 99 VAL A CG1 1 ATOM 540 C CG2 . VAL A 1 72 ? -68.070 -1.523 20.429 1.00 22.61 ? 99 VAL A CG2 1 ATOM 541 N N . ASP A 1 73 ? -66.916 -1.752 16.849 1.00 29.10 ? 100 ASP A N 1 ATOM 542 C CA . ASP A 1 73 ? -66.630 -2.450 15.607 1.00 31.26 ? 100 ASP A CA 1 ATOM 543 C C . ASP A 1 73 ? -67.215 -3.845 15.589 1.00 22.78 ? 100 ASP A C 1 ATOM 544 O O . ASP A 1 73 ? -67.657 -4.321 14.549 1.00 23.06 ? 100 ASP A O 1 ATOM 545 C CB . ASP A 1 73 ? -65.125 -2.499 15.349 1.00 38.83 ? 100 ASP A CB 1 ATOM 546 C CG . ASP A 1 73 ? -64.579 -1.171 14.863 1.00 54.03 ? 100 ASP A CG 1 ATOM 547 O OD1 . ASP A 1 73 ? -65.241 -0.132 15.092 1.00 43.35 ? 100 ASP A OD1 1 ATOM 548 O OD2 . ASP A 1 73 ? -63.490 -1.164 14.250 1.00 73.13 1 100 ASP A OD2 1 ATOM 549 N N . ARG A 1 74 ? -67.224 -4.499 16.741 1.00 20.63 ? 101 ARG A N 1 ATOM 550 C CA . ARG A 1 74 ? -67.630 -5.893 16.790 1.00 16.42 ? 101 ARG A CA 1 ATOM 551 C C . ARG A 1 74 ? -68.636 -6.191 17.894 1.00 13.66 ? 101 ARG A C 1 ATOM 552 O O . ARG A 1 74 ? -68.404 -5.882 19.057 1.00 15.98 ? 101 ARG A O 1 ATOM 553 C CB . ARG A 1 74 ? -66.405 -6.791 16.938 1.00 15.81 ? 101 ARG A CB 1 ATOM 554 C CG . ARG A 1 74 ? -66.742 -8.258 17.066 1.00 17.63 ? 101 ARG A CG 1 ATOM 555 C CD . ARG A 1 74 ? -65.491 -9.117 17.051 1.00 28.87 ? 101 ARG A CD 1 ATOM 556 N NE . ARG A 1 74 ? -65.439 -10.009 18.206 1.00 31.05 ? 101 ARG A NE 1 ATOM 557 C CZ . ARG A 1 74 ? -64.720 -9.772 19.299 1.00 34.95 ? 101 ARG A CZ 1 ATOM 558 N NH1 . ARG A 1 74 ? -64.737 -10.638 20.300 1.00 43.86 1 101 ARG A NH1 1 ATOM 559 N NH2 . ARG A 1 74 ? -63.981 -8.673 19.391 1.00 30.62 ? 101 ARG A NH2 1 ATOM 560 N N . VAL A 1 75 ? -69.758 -6.793 17.521 1.00 10.70 ? 102 VAL A N 1 ATOM 561 C CA . VAL A 1 75 ? -70.741 -7.230 18.499 1.00 8.15 ? 102 VAL A CA 1 ATOM 562 C C . VAL A 1 75 ? -70.800 -8.748 18.526 1.00 7.54 ? 102 VAL A C 1 ATOM 563 O O . VAL A 1 75 ? -70.872 -9.396 17.486 1.00 7.43 ? 102 VAL A O 1 ATOM 564 C CB . VAL A 1 75 ? -72.134 -6.678 18.197 1.00 6.86 ? 102 VAL A CB 1 ATOM 565 C CG1 . VAL A 1 75 ? -73.116 -7.135 19.254 1.00 6.42 ? 102 VAL A CG1 1 ATOM 566 C CG2 . VAL A 1 75 ? -72.093 -5.173 18.135 1.00 8.87 ? 102 VAL A CG2 1 ATOM 567 N N . GLN A 1 76 ? -70.763 -9.310 19.724 1.00 7.75 ? 103 GLN A N 1 ATOM 568 C CA . GLN A 1 76 ? -70.754 -10.752 19.886 1.00 8.48 ? 103 GLN A CA 1 ATOM 569 C C . GLN A 1 76 ? -71.819 -11.182 20.884 1.00 11.16 ? 103 GLN A C 1 ATOM 570 O O . GLN A 1 76 ? -71.818 -10.751 22.035 1.00 14.52 ? 103 GLN A O 1 ATOM 571 C CB . GLN A 1 76 ? -69.374 -11.209 20.352 1.00 11.18 ? 103 GLN A CB 1 ATOM 572 C CG . GLN A 1 76 ? -69.312 -12.641 20.845 1.00 14.22 ? 103 GLN A CG 1 ATOM 573 C CD . GLN A 1 76 ? -67.942 -12.998 21.398 1.00 22.61 ? 103 GLN A CD 1 ATOM 574 O OE1 . GLN A 1 76 ? -67.059 -12.142 21.491 1.00 24.55 ? 103 GLN A OE1 1 ATOM 575 N NE2 . GLN A 1 76 ? -67.758 -14.265 21.771 1.00 21.58 ? 103 GLN A NE2 1 ATOM 576 N N . MET A 1 77 ? -72.739 -12.025 20.435 1.00 8.73 ? 104 MET A N 1 ATOM 577 C CA . MET A 1 77 ? -73.781 -12.531 21.307 1.00 7.55 ? 104 MET A CA 1 ATOM 578 C C . MET A 1 77 ? -73.613 -14.026 21.514 1.00 9.58 ? 104 MET A C 1 ATOM 579 O O . MET A 1 77 ? -73.611 -14.792 20.555 1.00 9.10 ? 104 MET A O 1 ATOM 580 C CB . MET A 1 77 ? -75.149 -12.260 20.700 1.00 7.72 ? 104 MET A CB 1 ATOM 581 C CG . MET A 1 77 ? -75.411 -10.809 20.349 1.00 7.61 ? 104 MET A CG 1 ATOM 582 S SD . MET A 1 77 ? -77.167 -10.509 20.046 1.00 2.91 ? 104 MET A SD 1 ATOM 583 C CE . MET A 1 77 ? -77.170 -8.726 20.056 1.00 4.82 ? 104 MET A CE 1 ATOM 584 N N . ARG A 1 78 ? -73.476 -14.444 22.765 1.00 11.53 ? 105 ARG A N 1 ATOM 585 C CA . ARG A 1 78 ? -73.369 -15.862 23.069 1.00 11.76 ? 105 ARG A CA 1 ATOM 586 C C . ARG A 1 78 ? -74.536 -16.350 23.920 1.00 12.42 ? 105 ARG A C 1 ATOM 587 O O . ARG A 1 78 ? -74.957 -15.670 24.852 1.00 14.70 ? 105 ARG A O 1 ATOM 588 C CB . ARG A 1 78 ? -72.045 -16.162 23.764 1.00 16.92 ? 105 ARG A CB 1 ATOM 589 C CG . ARG A 1 78 ? -70.819 -15.915 22.899 1.00 22.97 ? 105 ARG A CG 1 ATOM 590 C CD . ARG A 1 78 ? -69.532 -16.153 23.688 1.00 29.30 ? 105 ARG A CD 1 ATOM 591 N NE . ARG A 1 78 ? -69.484 -17.496 24.258 1.00 36.55 ? 105 ARG A NE 1 ATOM 592 C CZ . ARG A 1 78 ? -68.582 -17.898 25.146 1.00 31.64 ? 105 ARG A CZ 1 ATOM 593 N NH1 . ARG A 1 78 ? -68.616 -19.138 25.611 1.00 35.99 1 105 ARG A NH1 1 ATOM 594 N NH2 . ARG A 1 78 ? -67.655 -17.055 25.574 1.00 28.97 ? 105 ARG A NH2 1 ATOM 595 N N . ARG A 1 79 ? -75.057 -17.524 23.572 1.00 12.58 ? 106 ARG A N 1 ATOM 596 C CA . ARG A 1 79 ? -76.127 -18.181 24.320 1.00 12.38 ? 106 ARG A CA 1 ATOM 597 C C . ARG A 1 79 ? -77.405 -17.354 24.384 1.00 10.44 ? 106 ARG A C 1 ATOM 598 O O . ARG A 1 79 ? -78.096 -17.350 25.399 1.00 11.86 ? 106 ARG A O 1 ATOM 599 C CB . ARG A 1 79 ? -75.665 -18.515 25.740 1.00 17.68 ? 106 ARG A CB 1 ATOM 600 C CG . ARG A 1 79 ? -74.491 -19.464 25.820 1.00 16.72 ? 106 ARG A CG 1 ATOM 601 C CD . ARG A 1 79 ? -73.939 -19.489 27.234 1.00 23.02 ? 106 ARG A CD 1 ATOM 602 N NE . ARG A 1 79 ? -75.004 -19.553 28.233 1.00 31.55 ? 106 ARG A NE 1 ATOM 603 C CZ . ARG A 1 79 ? -75.360 -20.658 28.882 1.00 37.61 ? 106 ARG A CZ 1 ATOM 604 N NH1 . ARG A 1 79 ? -76.341 -20.620 29.776 1.00 31.12 1 106 ARG A NH1 1 ATOM 605 N NH2 . ARG A 1 79 ? -74.729 -21.800 28.641 1.00 39.14 ? 106 ARG A NH2 1 ATOM 606 N N . CYS A 1 80 ? -77.728 -16.669 23.296 1.00 10.13 ? 107 CYS A N 1 ATOM 607 C CA . CYS A 1 80 ? -78.880 -15.776 23.292 1.00 12.11 ? 107 CYS A CA 1 ATOM 608 C C . CYS A 1 80 ? -80.137 -16.323 22.599 1.00 13.51 ? 107 CYS A C 1 ATOM 609 O O . CYS A 1 80 ? -80.050 -17.087 21.637 1.00 12.72 ? 107 CYS A O 1 ATOM 610 C CB . CYS A 1 80 ? -78.490 -14.428 22.692 1.00 10.51 ? 107 CYS A CB 1 ATOM 611 S SG . CYS A 1 80 ? -77.476 -13.436 23.802 1.00 13.83 ? 107 CYS A SG 1 ATOM 612 N N . MET A 1 81 ? -81.302 -15.928 23.113 1.00 14.23 ? 108 MET A N 1 ATOM 613 C CA . MET A 1 81 ? -82.571 -16.197 22.455 1.00 12.18 ? 108 MET A CA 1 ATOM 614 C C . MET A 1 81 ? -82.624 -15.349 21.204 1.00 12.40 ? 108 MET A C 1 ATOM 615 O O . MET A 1 81 ? -82.319 -14.160 21.256 1.00 11.81 ? 108 MET A O 1 ATOM 616 C CB . MET A 1 81 ? -83.750 -15.759 23.328 1.00 13.60 ? 108 MET A CB 1 ATOM 617 C CG . MET A 1 81 ? -83.857 -16.399 24.686 1.00 15.50 ? 108 MET A CG 1 ATOM 618 S SD . MET A 1 81 ? -84.047 -18.175 24.607 1.00 26.03 ? 108 MET A SD 1 ATOM 619 C CE . MET A 1 81 ? -82.564 -18.672 25.471 1.00 24.60 ? 108 MET A CE 1 ATOM 620 N N . LEU A 1 82 ? -83.010 -15.944 20.082 1.00 11.85 ? 109 LEU A N 1 ATOM 621 C CA . LEU A 1 82 ? -83.427 -15.146 18.943 1.00 11.24 ? 109 LEU A CA 1 ATOM 622 C C . LEU A 1 82 ? -84.630 -14.341 19.424 1.00 13.80 ? 109 LEU A C 1 ATOM 623 O O . LEU A 1 82 ? -85.513 -14.879 20.097 1.00 19.09 ? 109 LEU A O 1 ATOM 624 C CB . LEU A 1 82 ? -83.796 -16.036 17.756 1.00 11.53 ? 109 LEU A CB 1 ATOM 625 C CG . LEU A 1 82 ? -82.635 -16.661 16.977 1.00 9.67 ? 109 LEU A CG 1 ATOM 626 C CD1 . LEU A 1 82 ? -83.091 -17.890 16.205 1.00 8.58 ? 109 LEU A CD1 1 ATOM 627 C CD2 . LEU A 1 82 ? -82.025 -15.638 16.033 1.00 7.37 ? 109 LEU A CD2 1 ATOM 628 N N . PRO A 1 83 ? -84.657 -13.042 19.103 1.00 10.68 ? 110 PRO A N 1 ATOM 629 C CA . PRO A 1 83 ? -85.611 -12.092 19.686 1.00 13.48 ? 110 PRO A CA 1 ATOM 630 C C . PRO A 1 83 ? -87.010 -12.111 19.072 1.00 17.76 ? 110 PRO A C 1 ATOM 631 O O . PRO A 1 83 ? -87.512 -11.044 18.722 1.00 15.78 ? 110 PRO A O 1 ATOM 632 C CB . PRO A 1 83 ? -84.951 -10.744 19.412 1.00 13.55 ? 110 PRO A CB 1 ATOM 633 C CG . PRO A 1 83 ? -84.170 -10.967 18.170 1.00 11.22 ? 110 PRO A CG 1 ATOM 634 C CD . PRO A 1 83 ? -83.707 -12.388 18.189 1.00 8.93 ? 110 PRO A CD 1 ATOM 635 N N . GLY A 1 84 ? -87.620 -13.290 18.954 1.00 20.79 ? 111 GLY A N 1 ATOM 636 C CA . GLY A 1 84 ? -88.979 -13.430 18.447 1.00 19.96 ? 111 GLY A CA 1 ATOM 637 C C . GLY A 1 84 ? -89.236 -12.856 17.060 1.00 24.95 ? 111 GLY A C 1 ATOM 638 O O . GLY A 1 84 ? -88.613 -13.266 16.081 1.00 23.63 ? 111 GLY A O 1 ATOM 639 N N . HIS A 1 85 ? -90.177 -11.917 16.980 1.00 27.90 ? 112 HIS A N 1 ATOM 640 C CA . HIS A 1 85 ? -90.465 -11.200 15.744 1.00 22.38 ? 112 HIS A CA 1 ATOM 641 C C . HIS A 1 85 ? -89.875 -9.800 15.828 1.00 23.04 ? 112 HIS A C 1 ATOM 642 O O . HIS A 1 85 ? -90.405 -8.851 15.250 1.00 24.91 ? 112 HIS A O 1 ATOM 643 C CB . HIS A 1 85 ? -91.973 -11.087 15.524 1.00 29.63 ? 112 HIS A CB 1 ATOM 644 C CG . HIS A 1 85 ? -92.658 -12.395 15.278 1.00 35.02 ? 112 HIS A CG 1 ATOM 645 N ND1 . HIS A 1 85 ? -93.007 -13.256 16.296 1.00 40.97 ? 112 HIS A ND1 1 ATOM 646 C CD2 . HIS A 1 85 ? -93.078 -12.980 14.130 1.00 34.79 ? 112 HIS A CD2 1 ATOM 647 C CE1 . HIS A 1 85 ? -93.603 -14.320 15.785 1.00 44.93 ? 112 HIS A CE1 1 ATOM 648 N NE2 . HIS A 1 85 ? -93.658 -14.177 14.473 1.00 31.34 ? 112 HIS A NE2 1 ATOM 649 N N . THR A 1 86 ? -88.787 -9.669 16.573 1.00 20.68 ? 113 THR A N 1 ATOM 650 C CA . THR A 1 86 ? -88.138 -8.380 16.735 1.00 21.47 ? 113 THR A CA 1 ATOM 651 C C . THR A 1 86 ? -86.768 -8.445 16.086 1.00 19.26 ? 113 THR A C 1 ATOM 652 O O . THR A 1 86 ? -86.061 -9.431 16.251 1.00 18.75 ? 113 THR A O 1 ATOM 653 C CB . THR A 1 86 ? -87.982 -8.014 18.227 1.00 21.57 ? 113 THR A CB 1 ATOM 654 O OG1 . THR A 1 86 ? -89.264 -8.046 18.868 1.00 27.48 ? 113 THR A OG1 1 ATOM 655 C CG2 . THR A 1 86 ? -87.376 -6.631 18.386 1.00 20.80 ? 113 THR A CG2 1 ATOM 656 N N . PRO A 1 87 ? -86.403 -7.409 15.315 1.00 18.73 ? 114 PRO A N 1 ATOM 657 C CA . PRO A 1 87 ? -85.049 -7.323 14.768 1.00 14.49 ? 114 PRO A CA 1 ATOM 658 C C . PRO A 1 87 ? -84.029 -7.313 15.898 1.00 15.89 ? 114 PRO A C 1 ATOM 659 O O . PRO A 1 87 ? -84.252 -6.661 16.919 1.00 13.74 ? 114 PRO A O 1 ATOM 660 C CB . PRO A 1 87 ? -85.041 -5.963 14.068 1.00 15.49 ? 114 PRO A CB 1 ATOM 661 C CG . PRO A 1 87 ? -86.449 -5.693 13.740 1.00 19.51 ? 114 PRO A CG 1 ATOM 662 C CD . PRO A 1 87 ? -87.262 -6.311 14.839 1.00 23.72 ? 114 PRO A CD 1 ATOM 663 N N . ILE A 1 88 ? -82.930 -8.037 15.719 1.00 14.81 ? 115 ILE A N 1 ATOM 664 C CA . ILE A 1 88 ? -81.862 -8.042 16.704 1.00 11.42 ? 115 ILE A CA 1 ATOM 665 C C . ILE A 1 88 ? -81.337 -6.628 16.845 1.00 12.05 ? 115 ILE A C 1 ATOM 666 O O . ILE A 1 88 ? -80.981 -6.194 17.938 1.00 13.93 ? 115 ILE A O 1 ATOM 667 C CB . ILE A 1 88 ? -80.707 -8.940 16.270 1.00 9.56 ? 115 ILE A CB 1 ATOM 668 C CG1 . ILE A 1 88 ? -81.192 -10.372 16.046 1.00 8.83 ? 115 ILE A CG1 1 ATOM 669 C CG2 . ILE A 1 88 ? -79.613 -8.906 17.302 1.00 8.37 ? 115 ILE A CG2 1 ATOM 670 C CD1 . ILE A 1 88 ? -80.161 -11.264 15.386 1.00 5.88 ? 115 ILE A CD1 1 ATOM 671 N N . ALA A 1 89 ? -81.320 -5.903 15.728 1.00 11.72 ? 116 ALA A N 1 ATOM 672 C CA . ALA A 1 89 ? -80.848 -4.524 15.697 1.00 11.48 ? 116 ALA A CA 1 ATOM 673 C C . ALA A 1 89 ? -81.595 -3.633 16.680 1.00 13.84 ? 116 ALA A C 1 ATOM 674 O O . ALA A 1 89 ? -81.152 -2.530 16.979 1.00 15.34 ? 116 ALA A O 1 ATOM 675 C CB . ALA A 1 89 ? -80.957 -3.962 14.300 1.00 12.31 ? 116 ALA A CB 1 ATOM 676 N N . SER A 1 90 ? -82.733 -4.112 17.173 1.00 14.46 ? 117 SER A N 1 ATOM 677 C CA . SER A 1 90 ? -83.475 -3.397 18.199 1.00 15.71 ? 117 SER A CA 1 ATOM 678 C C . SER A 1 90 ? -82.701 -3.450 19.502 1.00 14.34 ? 117 SER A C 1 ATOM 679 O O . SER A 1 90 ? -82.452 -2.420 20.123 1.00 14.65 ? 117 SER A O 1 ATOM 680 C CB . SER A 1 90 ? -84.860 -4.010 18.395 1.00 18.03 ? 117 SER A CB 1 ATOM 681 O OG . SER A 1 90 ? -85.581 -4.047 17.177 1.00 20.29 ? 117 SER A OG 1 ATOM 682 N N . ILE A 1 91 ? -82.323 -4.659 19.906 1.00 14.13 ? 118 ILE A N 1 ATOM 683 C CA . ILE A 1 91 ? -81.530 -4.858 21.115 1.00 16.54 ? 118 ILE A CA 1 ATOM 684 C C . ILE A 1 91 ? -80.247 -4.029 21.054 1.00 15.25 ? 118 ILE A C 1 ATOM 685 O O . ILE A 1 91 ? -79.846 -3.406 22.037 1.00 17.53 ? 118 ILE A O 1 ATOM 686 C CB . ILE A 1 91 ? -81.174 -6.348 21.336 1.00 12.02 ? 118 ILE A CB 1 ATOM 687 C CG1 . ILE A 1 91 ? -82.393 -7.239 21.089 1.00 14.87 ? 118 ILE A CG1 1 ATOM 688 C CG2 . ILE A 1 91 ? -80.657 -6.567 22.738 1.00 7.94 ? 118 ILE A CG2 1 ATOM 689 C CD1 . ILE A 1 91 ? -82.143 -8.711 21.356 1.00 10.77 ? 118 ILE A CD1 1 ATOM 690 N N . LEU A 1 92 ? -79.621 -4.007 19.886 1.00 11.14 ? 119 LEU A N 1 ATOM 691 C CA . LEU A 1 92 ? -78.425 -3.207 19.690 1.00 12.79 ? 119 LEU A CA 1 ATOM 692 C C . LEU A 1 92 ? -78.720 -1.711 19.850 1.00 18.37 ? 119 LEU A C 1 ATOM 693 O O . LEU A 1 92 ? -77.876 -0.953 20.327 1.00 19.42 ? 119 LEU A O 1 ATOM 694 C CB . LEU A 1 92 ? -77.816 -3.503 18.320 1.00 15.16 ? 119 LEU A CB 1 ATOM 695 C CG . LEU A 1 92 ? -77.455 -4.969 18.068 1.00 10.37 ? 119 LEU A CG 1 ATOM 696 C CD1 . LEU A 1 92 ? -77.022 -5.193 16.637 1.00 9.02 ? 119 LEU A CD1 1 ATOM 697 C CD2 . LEU A 1 92 ? -76.360 -5.389 19.003 1.00 11.16 ? 119 LEU A CD2 1 ATOM 698 N N . ASP A 1 93 ? -79.919 -1.290 19.457 1.00 18.20 ? 120 ASP A N 1 ATOM 699 C CA . ASP A 1 93 ? -80.335 0.097 19.640 1.00 17.24 ? 120 ASP A CA 1 ATOM 700 C C . ASP A 1 93 ? -80.615 0.399 21.104 1.00 23.16 ? 120 ASP A C 1 ATOM 701 O O . ASP A 1 93 ? -80.303 1.487 21.594 1.00 23.52 ? 120 ASP A O 1 ATOM 702 C CB . ASP A 1 93 ? -81.584 0.397 18.818 1.00 14.69 ? 120 ASP A CB 1 ATOM 703 C CG . ASP A 1 93 ? -81.315 0.374 17.342 1.00 20.86 ? 120 ASP A CG 1 ATOM 704 O OD1 . ASP A 1 93 ? -80.138 0.552 16.960 1.00 23.55 ? 120 ASP A OD1 1 ATOM 705 O OD2 . ASP A 1 93 ? -82.272 0.170 16.566 1.00 21.30 1 120 ASP A OD2 1 ATOM 706 N N . TYR A 1 94 ? -81.219 -0.569 21.790 1.00 22.29 ? 121 TYR A N 1 ATOM 707 C CA . TYR A 1 94 ? -81.585 -0.423 23.191 1.00 18.15 ? 121 TYR A CA 1 ATOM 708 C C . TYR A 1 94 ? -80.345 -0.181 24.019 1.00 21.18 ? 121 TYR A C 1 ATOM 709 O O . TYR A 1 94 ? -80.351 0.652 24.924 1.00 29.35 ? 121 TYR A O 1 ATOM 710 C CB . TYR A 1 94 ? -82.313 -1.674 23.686 1.00 21.31 ? 121 TYR A CB 1 ATOM 711 C CG . TYR A 1 94 ? -82.784 -1.607 25.126 1.00 26.93 ? 121 TYR A CG 1 ATOM 712 C CD1 . TYR A 1 94 ? -83.874 -0.822 25.491 1.00 33.08 ? 121 TYR A CD1 1 ATOM 713 C CD2 . TYR A 1 94 ? -82.154 -2.349 26.117 1.00 26.55 ? 121 TYR A CD2 1 ATOM 714 C CE1 . TYR A 1 94 ? -84.314 -0.766 26.810 1.00 32.58 ? 121 TYR A CE1 1 ATOM 715 C CE2 . TYR A 1 94 ? -82.586 -2.302 27.437 1.00 32.16 ? 121 TYR A CE2 1 ATOM 716 C CZ . TYR A 1 94 ? -83.665 -1.509 27.779 1.00 31.72 ? 121 TYR A CZ 1 ATOM 717 O OH . TYR A 1 94 ? -84.089 -1.465 29.091 1.00 20.20 ? 121 TYR A OH 1 ATOM 718 N N . LEU A 1 95 ? -79.272 -0.898 23.695 1.00 19.76 ? 122 LEU A N 1 ATOM 719 C CA . LEU A 1 95 ? -78.020 -0.766 24.438 1.00 23.05 ? 122 LEU A CA 1 ATOM 720 C C . LEU A 1 95 ? -77.185 0.428 23.993 1.00 24.13 ? 122 LEU A C 1 ATOM 721 O O . LEU A 1 95 ? -76.130 0.695 24.562 1.00 27.38 ? 122 LEU A O 1 ATOM 722 C CB . LEU A 1 95 ? -77.196 -2.050 24.356 1.00 18.78 ? 122 LEU A CB 1 ATOM 723 C CG . LEU A 1 95 ? -77.788 -3.212 25.150 1.00 21.41 ? 122 LEU A CG 1 ATOM 724 C CD1 . LEU A 1 95 ? -76.954 -4.462 24.979 1.00 17.13 ? 122 LEU A CD1 1 ATOM 725 C CD2 . LEU A 1 95 ? -77.911 -2.840 26.619 1.00 27.85 ? 122 LEU A CD2 1 ATOM 726 N N . GLY A 1 96 ? -77.658 1.139 22.976 1.00 22.51 ? 123 GLY A N 1 ATOM 727 C CA . GLY A 1 96 ? -77.013 2.363 22.543 1.00 23.17 ? 123 GLY A CA 1 ATOM 728 C C . GLY A 1 96 ? -75.842 2.146 21.608 1.00 23.71 ? 123 GLY A C 1 ATOM 729 O O . GLY A 1 96 ? -75.069 3.074 21.352 1.00 23.14 ? 123 GLY A O 1 ATOM 730 N N . ILE A 1 97 ? -75.712 0.922 21.101 1.00 22.13 ? 124 ILE A N 1 ATOM 731 C CA . ILE A 1 97 ? -74.656 0.583 20.152 1.00 22.57 ? 124 ILE A CA 1 ATOM 732 C C . ILE A 1 97 ? -74.898 1.258 18.806 1.00 23.80 ? 124 ILE A C 1 ATOM 733 O O . ILE A 1 97 ? -76.038 1.380 18.360 1.00 26.66 ? 124 ILE A O 1 ATOM 734 C CB . ILE A 1 97 ? -74.569 -0.933 19.930 1.00 17.69 ? 124 ILE A CB 1 ATOM 735 C CG1 . ILE A 1 97 ? -74.708 -1.673 21.258 1.00 17.37 ? 124 ILE A CG1 1 ATOM 736 C CG2 . ILE A 1 97 ? -73.265 -1.294 19.240 1.00 22.35 ? 124 ILE A CG2 1 ATOM 737 C CD1 . ILE A 1 97 ? -74.428 -3.158 21.166 1.00 13.95 ? 124 ILE A CD1 1 ATOM 738 N N . VAL A 1 98 ? -73.825 1.698 18.159 1.00 22.35 ? 125 VAL A N 1 ATOM 739 C CA . VAL A 1 98 ? -73.952 2.403 16.891 1.00 24.44 ? 125 VAL A CA 1 ATOM 740 C C . VAL A 1 98 ? -72.995 1.860 15.831 1.00 29.21 ? 125 VAL A C 1 ATOM 741 O O . VAL A 1 98 ? -71.807 1.663 16.093 1.00 33.05 ? 125 VAL A O 1 ATOM 742 C CB . VAL A 1 98 ? -73.743 3.922 17.074 1.00 27.43 ? 125 VAL A CB 1 ATOM 743 C CG1 . VAL A 1 98 ? -73.582 4.611 15.731 1.00 35.01 ? 125 VAL A CG1 1 ATOM 744 C CG2 . VAL A 1 98 ? -74.904 4.525 17.845 1.00 25.40 ? 125 VAL A CG2 1 ATOM 745 N N . SER A 1 99 ? -73.539 1.617 14.640 1.00 28.05 ? 126 SER A N 1 ATOM 746 C CA . SER A 1 99 ? -72.786 1.137 13.476 1.00 26.12 ? 126 SER A CA 1 ATOM 747 C C . SER A 1 99 ? -71.721 0.066 13.751 1.00 19.28 ? 126 SER A C 1 ATOM 748 O O . SER A 1 99 ? -70.527 0.357 13.738 1.00 21.50 ? 126 SER A O 1 ATOM 749 C CB . SER A 1 99 ? -72.184 2.318 12.702 1.00 26.15 ? 126 SER A CB 1 ATOM 750 O OG . SER A 1 99 ? -71.476 3.193 13.562 1.00 32.25 ? 126 SER A OG 1 ATOM 751 N N . PRO A 1 100 ? -72.158 -1.174 14.015 1.00 16.06 ? 127 PRO A N 1 ATOM 752 C CA . PRO A 1 100 ? -71.232 -2.303 14.111 1.00 21.65 ? 127 PRO A CA 1 ATOM 753 C C . PRO A 1 100 ? -70.757 -2.772 12.741 1.00 27.10 ? 127 PRO A C 1 ATOM 754 O O . PRO A 1 100 ? -71.492 -2.671 11.756 1.00 23.61 ? 127 PRO A O 1 ATOM 755 C CB . PRO A 1 100 ? -72.082 -3.396 14.762 1.00 16.16 ? 127 PRO A CB 1 ATOM 756 C CG . PRO A 1 100 ? -73.174 -2.666 15.452 1.00 18.03 ? 127 PRO A CG 1 ATOM 757 C CD . PRO A 1 100 ? -73.481 -1.523 14.549 1.00 24.32 ? 127 PRO A CD 1 ATOM 758 N N . THR A 1 101 ? -69.528 -3.283 12.706 1.00 26.00 ? 128 THR A N 1 ATOM 759 C CA . THR A 1 101 ? -68.899 -3.808 11.504 1.00 17.93 ? 128 THR A CA 1 ATOM 760 C C . THR A 1 101 ? -69.063 -5.319 11.511 1.00 12.88 ? 128 THR A C 1 ATOM 761 O O . THR A 1 101 ? -69.143 -5.961 10.469 1.00 11.41 ? 128 THR A O 1 ATOM 762 C CB . THR A 1 101 ? -67.395 -3.464 11.512 1.00 28.71 ? 128 THR A CB 1 ATOM 763 O OG1 . THR A 1 101 ? -67.232 -2.041 11.560 1.00 38.06 ? 128 THR A OG1 1 ATOM 764 C CG2 . THR A 1 101 ? -66.682 -4.022 10.288 1.00 27.61 ? 128 THR A CG2 1 ATOM 765 N N . THR A 1 102 ? -69.125 -5.882 12.709 1.00 12.95 ? 129 THR A N 1 ATOM 766 C CA . THR A 1 102 ? -69.245 -7.321 12.866 1.00 12.72 ? 129 THR A CA 1 ATOM 767 C C . THR A 1 102 ? -70.339 -7.679 13.856 1.00 11.88 ? 129 THR A C 1 ATOM 768 O O . THR A 1 102 ? -70.375 -7.152 14.966 1.00 13.50 ? 129 THR A O 1 ATOM 769 C CB . THR A 1 102 ? -67.941 -7.917 13.391 1.00 13.14 ? 129 THR A CB 1 ATOM 770 O OG1 . THR A 1 102 ? -66.870 -7.548 12.518 1.00 20.21 ? 129 THR A OG1 1 ATOM 771 C CG2 . THR A 1 102 ? -68.038 -9.436 13.482 1.00 10.16 ? 129 THR A CG2 1 ATOM 772 N N . LEU A 1 103 ? -71.237 -8.569 13.451 1.00 8.20 ? 130 LEU A N 1 ATOM 773 C CA . LEU A 1 103 ? -72.166 -9.170 14.393 1.00 7.39 ? 130 LEU A CA 1 ATOM 774 C C . LEU A 1 103 ? -71.889 -10.656 14.453 1.00 7.06 ? 130 LEU A C 1 ATOM 775 O O . LEU A 1 103 ? -71.824 -11.322 13.421 1.00 6.59 ? 130 LEU A O 1 ATOM 776 C CB . LEU A 1 103 ? -73.623 -8.939 13.992 1.00 6.21 ? 130 LEU A CB 1 ATOM 777 C CG . LEU A 1 103 ? -74.627 -9.651 14.910 1.00 3.98 ? 130 LEU A CG 1 ATOM 778 C CD1 . LEU A 1 103 ? -75.030 -8.790 16.083 1.00 4.05 ? 130 LEU A CD1 1 ATOM 779 C CD2 . LEU A 1 103 ? -75.846 -10.092 14.150 1.00 4.55 ? 130 LEU A CD2 1 ATOM 780 N N . ILE A 1 104 ? -71.718 -11.178 15.661 1.00 7.01 ? 131 ILE A N 1 ATOM 781 C CA . ILE A 1 104 ? -71.521 -12.607 15.830 1.00 6.39 ? 131 ILE A CA 1 ATOM 782 C C . ILE A 1 104 ? -72.612 -13.206 16.697 1.00 6.08 ? 131 ILE A C 1 ATOM 783 O O . ILE A 1 104 ? -72.718 -12.894 17.878 1.00 7.78 ? 131 ILE A O 1 ATOM 784 C CB . ILE A 1 104 ? -70.142 -12.934 16.416 1.00 7.91 ? 131 ILE A CB 1 ATOM 785 C CG1 . ILE A 1 104 ? -69.052 -12.671 15.364 1.00 10.11 ? 131 ILE A CG1 1 ATOM 786 C CG2 . ILE A 1 104 ? -70.117 -14.371 16.897 1.00 8.20 ? 131 ILE A CG2 1 ATOM 787 C CD1 . ILE A 1 104 ? -67.702 -13.310 15.657 1.00 13.95 ? 131 ILE A CD1 1 ATOM 788 N N . PHE A 1 105 ? -73.434 -14.056 16.093 1.00 5.23 ? 132 PHE A N 1 ATOM 789 C CA . PHE A 1 105 ? -74.513 -14.706 16.815 1.00 4.58 ? 132 PHE A CA 1 ATOM 790 C C . PHE A 1 105 ? -74.191 -16.182 17.007 1.00 4.95 ? 132 PHE A C 1 ATOM 791 O O . PHE A 1 105 ? -74.129 -16.951 16.047 1.00 3.90 ? 132 PHE A O 1 ATOM 792 C CB . PHE A 1 105 ? -75.853 -14.521 16.097 1.00 4.59 ? 132 PHE A CB 1 ATOM 793 C CG . PHE A 1 105 ? -77.034 -14.610 17.013 1.00 4.60 ? 132 PHE A CG 1 ATOM 794 C CD1 . PHE A 1 105 ? -77.527 -13.474 17.636 1.00 4.62 ? 132 PHE A CD1 1 ATOM 795 C CD2 . PHE A 1 105 ? -77.629 -15.830 17.282 1.00 4.77 ? 132 PHE A CD2 1 ATOM 796 C CE1 . PHE A 1 105 ? -78.597 -13.547 18.500 1.00 4.46 ? 132 PHE A CE1 1 ATOM 797 C CE2 . PHE A 1 105 ? -78.699 -15.912 18.143 1.00 6.90 ? 132 PHE A CE2 1 ATOM 798 C CZ . PHE A 1 105 ? -79.186 -14.766 18.752 1.00 8.02 ? 132 PHE A CZ 1 ATOM 799 N N . GLU A 1 106 ? -73.994 -16.568 18.262 1.00 7.25 ? 133 GLU A N 1 ATOM 800 C CA . GLU A 1 106 ? -73.459 -17.883 18.589 1.00 10.52 ? 133 GLU A CA 1 ATOM 801 C C . GLU A 1 106 ? -74.155 -18.464 19.811 1.00 8.13 ? 133 GLU A C 1 ATOM 802 O O . GLU A 1 106 ? -73.723 -18.250 20.934 1.00 11.68 ? 133 GLU A O 1 ATOM 803 C CB . GLU A 1 106 ? -71.954 -17.758 18.840 1.00 13.88 ? 133 GLU A CB 1 ATOM 804 C CG . GLU A 1 106 ? -71.235 -19.044 19.192 1.00 21.58 ? 133 GLU A CG 1 ATOM 805 C CD . GLU A 1 106 ? -69.776 -18.804 19.544 1.00 28.84 ? 133 GLU A CD 1 ATOM 806 O OE1 . GLU A 1 106 ? -69.318 -19.341 20.575 1.00 32.32 ? 133 GLU A OE1 1 ATOM 807 O OE2 . GLU A 1 106 ? -69.089 -18.075 18.792 1.00 26.18 1 133 GLU A OE2 1 ATOM 808 N N . SER A 1 107 ? -75.235 -19.200 19.588 1.00 6.43 ? 134 SER A N 1 ATOM 809 C CA . SER A 1 107 ? -76.035 -19.715 20.686 1.00 7.63 ? 134 SER A CA 1 ATOM 810 C C . SER A 1 107 ? -76.487 -21.134 20.440 1.00 8.18 ? 134 SER A C 1 ATOM 811 O O . SER A 1 107 ? -76.461 -21.611 19.320 1.00 9.75 ? 134 SER A O 1 ATOM 812 C CB . SER A 1 107 ? -77.279 -18.860 20.876 1.00 9.50 ? 134 SER A CB 1 ATOM 813 O OG . SER A 1 107 ? -78.358 -19.669 21.314 1.00 8.96 ? 134 SER A OG 1 ATOM 814 N N . ASP A 1 108 ? -76.917 -21.806 21.497 1.00 8.85 ? 135 ASP A N 1 ATOM 815 C CA . ASP A 1 108 ? -77.551 -23.103 21.353 1.00 9.00 ? 135 ASP A CA 1 ATOM 816 C C . ASP A 1 108 ? -78.893 -23.060 22.048 1.00 13.68 ? 135 ASP A C 1 ATOM 817 O O . ASP A 1 108 ? -79.557 -24.081 22.224 1.00 17.06 ? 135 ASP A O 1 ATOM 818 C CB . ASP A 1 108 ? -76.675 -24.204 21.926 1.00 7.69 ? 135 ASP A CB 1 ATOM 819 C CG . ASP A 1 108 ? -75.377 -24.336 21.186 1.00 10.88 ? 135 ASP A CG 1 ATOM 820 O OD1 . ASP A 1 108 ? -75.382 -24.900 20.078 1.00 10.99 ? 135 ASP A OD1 1 ATOM 821 O OD2 . ASP A 1 108 ? -74.349 -23.863 21.700 1.00 17.57 1 135 ASP A OD2 1 ATOM 822 N N . ASN A 1 109 ? -79.282 -21.858 22.451 1.00 11.88 ? 136 ASN A N 1 ATOM 823 C CA . ASN A 1 109 ? -80.601 -21.641 23.002 1.00 11.19 ? 136 ASN A CA 1 ATOM 824 C C . ASN A 1 109 ? -81.273 -20.529 22.232 1.00 15.48 ? 136 ASN A C 1 ATOM 825 O O . ASN A 1 109 ? -81.361 -19.395 22.708 1.00 12.97 ? 136 ASN A O 1 ATOM 826 C CB . ASN A 1 109 ? -80.519 -21.292 24.475 1.00 13.74 ? 136 ASN A CB 1 ATOM 827 C CG . ASN A 1 109 ? -81.577 -21.993 25.280 1.00 26.28 ? 136 ASN A CG 1 ATOM 828 O OD1 . ASN A 1 109 ? -81.272 -22.737 26.218 1.00 36.71 ? 136 ASN A OD1 1 ATOM 829 N ND2 . ASN A 1 109 ? -82.836 -21.789 24.902 1.00 23.52 ? 136 ASN A ND2 1 ATOM 830 N N . LEU A 1 110 ? -81.737 -20.874 21.031 1.00 15.55 ? 137 LEU A N 1 ATOM 831 C CA . LEU A 1 110 ? -82.266 -19.909 20.077 1.00 9.19 ? 137 LEU A CA 1 ATOM 832 C C . LEU A 1 110 ? -83.732 -19.594 20.349 1.00 10.03 ? 137 LEU A C 1 ATOM 833 O O . LEU A 1 110 ? -84.136 -18.434 20.358 1.00 11.04 ? 137 LEU A O 1 ATOM 834 C CB . LEU A 1 110 ? -82.088 -20.439 18.652 1.00 8.53 ? 137 LEU A CB 1 ATOM 835 C CG . LEU A 1 110 ? -80.665 -20.809 18.219 1.00 9.07 ? 137 LEU A CG 1 ATOM 836 C CD1 . LEU A 1 110 ? -80.637 -21.389 16.817 1.00 7.59 ? 137 LEU A CD1 1 ATOM 837 C CD2 . LEU A 1 110 ? -79.745 -19.607 18.300 1.00 9.09 ? 137 LEU A CD2 1 ATOM 838 N N . GLY A 1 111 ? -84.528 -20.632 20.576 1.00 11.14 ? 138 GLY A N 1 ATOM 839 C CA . GLY A 1 111 ? -85.950 -20.457 20.806 1.00 11.14 ? 138 GLY A CA 1 ATOM 840 C C . GLY A 1 111 ? -86.763 -20.563 19.528 1.00 12.93 ? 138 GLY A C 1 ATOM 841 O O . GLY A 1 111 ? -87.967 -20.821 19.567 1.00 13.76 ? 138 GLY A O 1 ATOM 842 N N . MET A 1 112 ? -86.098 -20.364 18.393 1.00 13.82 ? 139 MET A N 1 ATOM 843 C CA . MET A 1 112 ? -86.745 -20.428 17.088 1.00 11.63 ? 139 MET A CA 1 ATOM 844 C C . MET A 1 112 ? -85.749 -20.706 15.963 1.00 12.70 ? 139 MET A C 1 ATOM 845 O O . MET A 1 112 ? -84.697 -21.313 16.172 1.00 11.19 ? 139 MET A O 1 ATOM 846 C CB . MET A 1 112 ? -87.508 -19.128 16.803 1.00 11.58 ? 139 MET A CB 1 ATOM 847 C CG . MET A 1 112 ? -86.680 -17.857 16.985 1.00 11.95 ? 139 MET A CG 1 ATOM 848 S SD . MET A 1 112 ? -87.615 -16.306 16.858 1.00 10.39 ? 139 MET A SD 1 ATOM 849 C CE . MET A 1 112 ? -88.171 -16.389 15.162 1.00 10.51 ? 139 MET A CE 1 ATOM 850 N N . ASN A 1 113 ? -86.112 -20.278 14.761 1.00 13.20 ? 140 ASN A N 1 ATOM 851 C CA . ASN A 1 113 ? -85.241 -20.368 13.605 1.00 10.77 ? 140 ASN A CA 1 ATOM 852 C C . ASN A 1 113 ? -84.924 -18.960 13.148 1.00 10.10 ? 140 ASN A C 1 ATOM 853 O O . ASN A 1 113 ? -85.746 -18.053 13.284 1.00 7.53 ? 140 ASN A O 1 ATOM 854 C CB . ASN A 1 113 ? -85.918 -21.131 12.468 1.00 15.35 ? 140 ASN A CB 1 ATOM 855 C CG . ASN A 1 113 ? -86.070 -22.608 12.759 1.00 21.62 ? 140 ASN A CG 1 ATOM 856 O OD1 . ASN A 1 113 ? -85.106 -23.279 13.127 1.00 26.39 ? 140 ASN A OD1 1 ATOM 857 N ND2 . ASN A 1 113 ? -87.294 -23.123 12.607 1.00 29.20 ? 140 ASN A ND2 1 ATOM 858 N N . ILE A 1 114 ? -83.726 -18.780 12.610 1.00 11.84 ? 141 ILE A N 1 ATOM 859 C CA . ILE A 1 114 ? -83.268 -17.469 12.173 1.00 9.85 ? 141 ILE A CA 1 ATOM 860 C C . ILE A 1 114 ? -84.157 -16.975 11.026 1.00 9.84 ? 141 ILE A C 1 ATOM 861 O O . ILE A 1 114 ? -84.630 -17.767 10.217 1.00 11.09 ? 141 ILE A O 1 ATOM 862 C CB . ILE A 1 114 ? -81.772 -17.539 11.769 1.00 8.61 ? 141 ILE A CB 1 ATOM 863 C CG1 . ILE A 1 114 ? -81.201 -16.153 11.453 1.00 7.13 ? 141 ILE A CG1 1 ATOM 864 C CG2 . ILE A 1 114 ? -81.569 -18.529 10.631 1.00 10.17 ? 141 ILE A CG2 1 ATOM 865 C CD1 . ILE A 1 114 ? -80.452 -15.522 12.597 1.00 3.86 ? 141 ILE A CD1 1 ATOM 866 N N . THR A 1 115 ? -84.432 -15.673 10.991 1.00 9.15 ? 142 THR A N 1 ATOM 867 C CA . THR A 1 115 ? -85.283 -15.092 9.955 1.00 8.25 ? 142 THR A CA 1 ATOM 868 C C . THR A 1 115 ? -84.660 -13.804 9.435 1.00 8.74 ? 142 THR A C 1 ATOM 869 O O . THR A 1 115 ? -83.919 -13.147 10.162 1.00 9.04 ? 142 THR A O 1 ATOM 870 C CB . THR A 1 115 ? -86.686 -14.744 10.492 1.00 9.70 ? 142 THR A CB 1 ATOM 871 O OG1 . THR A 1 115 ? -86.732 -13.357 10.852 1.00 11.19 ? 142 THR A OG1 1 ATOM 872 C CG2 . THR A 1 115 ? -87.045 -15.592 11.707 1.00 8.68 ? 142 THR A CG2 1 ATOM 873 N N . ARG A 1 116 ? -84.974 -13.439 8.190 1.00 8.85 ? 143 ARG A N 1 ATOM 874 C CA . ARG A 1 116 ? -84.437 -12.221 7.577 1.00 8.00 ? 143 ARG A CA 1 ATOM 875 C C . ARG A 1 116 ? -84.752 -10.983 8.414 1.00 10.99 ? 143 ARG A C 1 ATOM 876 O O . ARG A 1 116 ? -84.001 -10.005 8.413 1.00 12.82 ? 143 ARG A O 1 ATOM 877 C CB . ARG A 1 116 ? -84.956 -12.039 6.146 1.00 6.70 ? 143 ARG A CB 1 ATOM 878 C CG . ARG A 1 116 ? -85.463 -10.620 5.858 1.00 16.80 ? 143 ARG A CG 1 ATOM 879 C CD . ARG A 1 116 ? -85.451 -10.236 4.378 1.00 23.19 ? 143 ARG A CD 1 ATOM 880 N NE . ARG A 1 116 ? -86.544 -10.843 3.616 1.00 45.05 ? 143 ARG A NE 1 ATOM 881 C CZ . ARG A 1 116 ? -87.629 -10.195 3.195 1.00 36.39 ? 143 ARG A CZ 1 ATOM 882 N NH1 . ARG A 1 116 ? -88.562 -10.849 2.508 1.00 27.36 1 143 ARG A NH1 1 ATOM 883 N NH2 . ARG A 1 116 ? -87.780 -8.898 3.452 1.00 28.77 ? 143 ARG A NH2 1 ATOM 884 N N . GLN A 1 117 ? -85.855 -11.044 9.150 1.00 12.17 ? 144 GLN A N 1 ATOM 885 C CA . GLN A 1 117 ? -86.329 -9.896 9.911 1.00 12.70 ? 144 GLN A CA 1 ATOM 886 C C . GLN A 1 117 ? -85.409 -9.572 11.066 1.00 11.68 ? 144 GLN A C 1 ATOM 887 O O . GLN A 1 117 ? -85.340 -8.427 11.507 1.00 13.82 ? 144 GLN A O 1 ATOM 888 C CB . GLN A 1 117 ? -87.737 -10.141 10.442 1.00 16.43 ? 144 GLN A CB 1 ATOM 889 C CG . GLN A 1 117 ? -88.427 -8.878 10.913 1.00 15.91 ? 144 GLN A CG 1 ATOM 890 C CD . GLN A 1 117 ? -89.318 -9.132 12.099 1.00 20.55 ? 144 GLN A CD 1 ATOM 891 O OE1 . GLN A 1 117 ? -89.699 -10.274 12.371 1.00 21.79 ? 144 GLN A OE1 1 ATOM 892 N NE2 . GLN A 1 117 ? -89.644 -8.069 12.829 1.00 24.72 ? 144 GLN A NE2 1 ATOM 893 N N . HIS A 1 118 ? -84.711 -10.589 11.558 1.00 12.83 ? 145 HIS A N 1 ATOM 894 C CA . HIS A 1 118 ? -83.719 -10.411 12.614 1.00 13.52 ? 145 HIS A CA 1 ATOM 895 C C . HIS A 1 118 ? -82.606 -9.469 12.146 1.00 15.44 ? 145 HIS A C 1 ATOM 896 O O . HIS A 1 118 ? -81.982 -8.754 12.941 1.00 12.09 ? 145 HIS A O 1 ATOM 897 C CB . HIS A 1 118 ? -83.117 -11.762 12.993 1.00 9.14 ? 145 HIS A CB 1 ATOM 898 C CG . HIS A 1 118 ? -84.076 -12.689 13.673 1.00 8.95 ? 145 HIS A CG 1 ATOM 899 N ND1 . HIS A 1 118 ? -84.917 -12.281 14.686 1.00 9.67 ? 145 HIS A ND1 1 ATOM 900 C CD2 . HIS A 1 118 ? -84.306 -14.012 13.505 1.00 8.39 ? 145 HIS A CD2 1 ATOM 901 C CE1 . HIS A 1 118 ? -85.631 -13.310 15.104 1.00 8.99 ? 145 HIS A CE1 1 ATOM 902 N NE2 . HIS A 1 118 ? -85.280 -14.373 14.404 1.00 8.82 ? 145 HIS A NE2 1 ATOM 903 N N . LEU A 1 119 ? -82.386 -9.465 10.838 1.00 14.17 ? 146 LEU A N 1 ATOM 904 C CA . LEU A 1 119 ? -81.283 -8.740 10.242 1.00 12.16 ? 146 LEU A CA 1 ATOM 905 C C . LEU A 1 119 ? -81.720 -7.448 9.583 1.00 12.75 ? 146 LEU A C 1 ATOM 906 O O . LEU A 1 119 ? -81.099 -6.998 8.627 1.00 18.41 ? 146 LEU A O 1 ATOM 907 C CB . LEU A 1 119 ? -80.601 -9.629 9.211 1.00 13.76 ? 146 LEU A CB 1 ATOM 908 C CG . LEU A 1 119 ? -79.917 -10.853 9.813 1.00 13.39 ? 146 LEU A CG 1 ATOM 909 C CD1 . LEU A 1 119 ? -79.671 -11.914 8.751 1.00 11.81 ? 146 LEU A CD1 1 ATOM 910 C CD2 . LEU A 1 119 ? -78.615 -10.427 10.475 1.00 10.00 ? 146 LEU A CD2 1 ATOM 911 N N . ASP A 1 120 ? -82.789 -6.845 10.075 1.00 12.54 ? 147 ASP A N 1 ATOM 912 C CA . ASP A 1 120 ? -83.180 -5.553 9.539 1.00 17.46 ? 147 ASP A CA 1 ATOM 913 C C . ASP A 1 120 ? -82.300 -4.510 10.203 1.00 15.81 ? 147 ASP A C 1 ATOM 914 O O . ASP A 1 120 ? -81.986 -4.641 11.386 1.00 13.93 ? 147 ASP A O 1 ATOM 915 C CB . ASP A 1 120 ? -84.664 -5.277 9.787 1.00 16.41 ? 147 ASP A CB 1 ATOM 916 C CG . ASP A 1 120 ? -85.571 -6.234 9.027 1.00 23.05 ? 147 ASP A CG 1 ATOM 917 O OD1 . ASP A 1 120 ? -85.118 -6.807 8.007 1.00 21.33 ? 147 ASP A OD1 1 ATOM 918 O OD2 . ASP A 1 120 ? -86.739 -6.409 9.445 1.00 27.23 1 147 ASP A OD2 1 ATOM 919 N N . ARG A 1 121 ? -81.885 -3.507 9.427 1.00 15.22 ? 148 ARG A N 1 ATOM 920 C CA . ARG A 1 121 ? -81.023 -2.411 9.888 1.00 16.80 ? 148 ARG A CA 1 ATOM 921 C C . ARG A 1 121 ? -79.569 -2.846 10.119 1.00 20.42 ? 148 ARG A C 1 ATOM 922 O O . ARG A 1 121 ? -78.703 -2.043 10.489 1.00 17.35 ? 148 ARG A O 1 ATOM 923 C CB . ARG A 1 121 ? -81.584 -1.740 11.148 1.00 14.93 ? 148 ARG A CB 1 ATOM 924 C CG . ARG A 1 121 ? -83.025 -1.331 11.051 1.00 10.43 ? 148 ARG A CG 1 ATOM 925 C CD . ARG A 1 121 ? -83.394 -0.437 12.209 1.00 13.33 ? 148 ARG A CD 1 ATOM 926 N NE . ARG A 1 121 ? -83.417 -1.152 13.477 1.00 13.37 ? 148 ARG A NE 1 ATOM 927 C CZ . ARG A 1 121 ? -84.492 -1.769 13.954 1.00 16.73 ? 148 ARG A CZ 1 ATOM 928 N NH1 . ARG A 1 121 ? -85.622 -1.762 13.260 1.00 18.34 1 148 ARG A NH1 1 ATOM 929 N NH2 . ARG A 1 121 ? -84.442 -2.396 15.120 1.00 18.22 ? 148 ARG A NH2 1 ATOM 930 N N . LEU A 1 122 ? -79.310 -4.128 9.915 1.00 18.23 ? 149 LEU A N 1 ATOM 931 C CA . LEU A 1 122 ? -77.955 -4.639 9.987 1.00 18.06 ? 149 LEU A CA 1 ATOM 932 C C . LEU A 1 122 ? -77.562 -5.030 8.575 1.00 24.34 ? 149 LEU A C 1 ATOM 933 O O . LEU A 1 122 ? -76.873 -6.027 8.349 1.00 21.29 ? 149 LEU A O 1 ATOM 934 C CB . LEU A 1 122 ? -77.870 -5.830 10.942 1.00 14.17 ? 149 LEU A CB 1 ATOM 935 C CG . LEU A 1 122 ? -78.284 -5.496 12.373 1.00 10.21 ? 149 LEU A CG 1 ATOM 936 C CD1 . LEU A 1 122 ? -78.277 -6.730 13.247 1.00 7.39 ? 149 LEU A CD1 1 ATOM 937 C CD2 . LEU A 1 122 ? -77.379 -4.422 12.937 1.00 9.08 ? 149 LEU A CD2 1 ATOM 938 N N . HIS A 1 123 ? -78.040 -4.235 7.624 1.00 28.83 ? 150 HIS A N 1 ATOM 939 C CA . HIS A 1 123 ? -77.666 -4.392 6.233 1.00 25.12 ? 150 HIS A CA 1 ATOM 940 C C . HIS A 1 123 ? -76.282 -3.785 5.993 1.00 22.69 ? 150 HIS A C 1 ATOM 941 O O . HIS A 1 123 ? -75.575 -4.189 5.069 1.00 23.25 ? 150 HIS A O 1 ATOM 942 C CB . HIS A 1 123 ? -78.712 -3.743 5.326 1.00 24.77 ? 150 HIS A CB 1 ATOM 943 C CG . HIS A 1 123 ? -80.011 -4.487 5.267 1.00 28.50 ? 150 HIS A CG 1 ATOM 944 N ND1 . HIS A 1 123 ? -80.186 -5.730 5.839 1.00 28.63 ? 150 HIS A ND1 1 ATOM 945 C CD2 . HIS A 1 123 ? -81.196 -4.166 4.695 1.00 35.33 ? 150 HIS A CD2 1 ATOM 946 C CE1 . HIS A 1 123 ? -81.424 -6.141 5.623 1.00 29.88 ? 150 HIS A CE1 1 ATOM 947 N NE2 . HIS A 1 123 ? -82.058 -5.210 4.932 1.00 33.96 ? 150 HIS A NE2 1 ATOM 948 N N . GLY A 1 124 ? -75.893 -2.833 6.841 1.00 18.68 ? 151 GLY A N 1 ATOM 949 C CA . GLY A 1 124 ? -74.601 -2.172 6.731 1.00 26.32 ? 151 GLY A CA 1 ATOM 950 C C . GLY A 1 124 ? -73.391 -3.001 7.146 1.00 23.16 ? 151 GLY A C 1 ATOM 951 O O . GLY A 1 124 ? -72.242 -2.581 6.964 1.00 14.66 ? 151 GLY A O 1 ATOM 952 N N . LEU A 1 125 ? -73.657 -4.184 7.696 1.00 22.91 ? 152 LEU A N 1 ATOM 953 C CA . LEU A 1 125 ? -72.621 -5.089 8.195 1.00 16.23 ? 152 LEU A CA 1 ATOM 954 C C . LEU A 1 125 ? -71.560 -5.456 7.162 1.00 14.19 ? 152 LEU A C 1 ATOM 955 O O . LEU A 1 125 ? -71.823 -5.477 5.965 1.00 18.47 ? 152 LEU A O 1 ATOM 956 C CB . LEU A 1 125 ? -73.259 -6.376 8.726 1.00 13.57 ? 152 LEU A CB 1 ATOM 957 C CG . LEU A 1 125 ? -73.991 -6.328 10.067 1.00 14.87 ? 152 LEU A CG 1 ATOM 958 C CD1 . LEU A 1 125 ? -74.336 -7.739 10.510 1.00 13.97 ? 152 LEU A CD1 1 ATOM 959 C CD2 . LEU A 1 125 ? -73.172 -5.617 11.143 1.00 14.03 ? 152 LEU A CD2 1 ATOM 960 N N . LYS A 1 126 ? -70.361 -5.761 7.643 1.00 12.90 ? 153 LYS A N 1 ATOM 961 C CA . LYS A 1 126 ? -69.295 -6.251 6.784 1.00 12.89 ? 153 LYS A CA 1 ATOM 962 C C . LYS A 1 126 ? -68.993 -7.700 7.123 1.00 12.72 ? 153 LYS A C 1 ATOM 963 O O . LYS A 1 126 ? -68.474 -8.454 6.298 1.00 13.53 ? 153 LYS A O 1 ATOM 964 C CB . LYS A 1 126 ? -68.040 -5.404 6.956 1.00 12.46 ? 153 LYS A CB 1 ATOM 965 C CG . LYS A 1 126 ? -68.156 -4.022 6.370 1.00 12.87 ? 153 LYS A CG 1 ATOM 966 C CD . LYS A 1 126 ? -66.910 -3.218 6.640 1.00 16.92 ? 153 LYS A CD 1 ATOM 967 C CE . LYS A 1 126 ? -66.648 -2.258 5.501 1.00 34.86 ? 153 LYS A CE 1 ATOM 968 N NZ . LYS A 1 126 ? -66.704 -2.971 4.191 1.00 40.68 1 153 LYS A NZ 1 ATOM 969 N N . ARG A 1 127 ? -69.330 -8.088 8.345 1.00 9.85 ? 154 ARG A N 1 ATOM 970 C CA . ARG A 1 127 ? -69.039 -9.428 8.809 1.00 10.38 ? 154 ARG A CA 1 ATOM 971 C C . ARG A 1 127 ? -70.192 -9.951 9.655 1.00 10.84 ? 154 ARG A C 1 ATOM 972 O O . ARG A 1 127 ? -70.632 -9.287 10.591 1.00 12.19 ? 154 ARG A O 1 ATOM 973 C CB . ARG A 1 127 ? -67.740 -9.412 9.609 1.00 13.26 ? 154 ARG A CB 1 ATOM 974 C CG . ARG A 1 127 ? -67.227 -10.768 10.065 1.00 16.58 ? 154 ARG A CG 1 ATOM 975 C CD . ARG A 1 127 ? -65.897 -10.582 10.800 1.00 32.72 ? 154 ARG A CD 1 ATOM 976 N NE . ARG A 1 127 ? -65.544 -11.710 11.660 1.00 38.83 ? 154 ARG A NE 1 ATOM 977 C CZ . ARG A 1 127 ? -64.582 -12.586 11.391 1.00 31.96 ? 154 ARG A CZ 1 ATOM 978 N NH1 . ARG A 1 127 ? -63.868 -12.466 10.278 1.00 22.69 1 154 ARG A NH1 1 ATOM 979 N NH2 . ARG A 1 127 ? -64.331 -13.580 12.237 1.00 29.61 ? 154 ARG A NH2 1 ATOM 980 N N . PHE A 1 128 ? -70.687 -11.136 9.311 1.00 7.64 ? 155 PHE A N 1 ATOM 981 C CA . PHE A 1 128 ? -71.738 -11.791 10.079 1.00 5.40 ? 155 PHE A CA 1 ATOM 982 C C . PHE A 1 128 ? -71.390 -13.254 10.309 1.00 6.59 ? 155 PHE A C 1 ATOM 983 O O . PHE A 1 128 ? -70.969 -13.942 9.382 1.00 7.90 ? 155 PHE A O 1 ATOM 984 C CB . PHE A 1 128 ? -73.071 -11.692 9.339 1.00 5.11 ? 155 PHE A CB 1 ATOM 985 C CG . PHE A 1 128 ? -74.174 -12.531 9.944 1.00 5.52 ? 155 PHE A CG 1 ATOM 986 C CD1 . PHE A 1 128 ? -74.855 -12.099 11.074 1.00 3.96 ? 155 PHE A CD1 1 ATOM 987 C CD2 . PHE A 1 128 ? -74.542 -13.742 9.371 1.00 4.11 ? 155 PHE A CD2 1 ATOM 988 C CE1 . PHE A 1 128 ? -75.862 -12.860 11.622 1.00 2.15 ? 155 PHE A CE1 1 ATOM 989 C CE2 . PHE A 1 128 ? -75.551 -14.504 9.921 1.00 2.91 ? 155 PHE A CE2 1 ATOM 990 C CZ . PHE A 1 128 ? -76.210 -14.060 11.048 1.00 2.89 ? 155 PHE A CZ 1 ATOM 991 N N . ARG A 1 129 ? -71.557 -13.733 11.537 1.00 2.90 ? 156 ARG A N 1 ATOM 992 C CA . ARG A 1 129 ? -71.397 -15.155 11.809 1.00 2.99 ? 156 ARG A CA 1 ATOM 993 C C . ARG A 1 129 ? -72.535 -15.662 12.654 1.00 3.37 ? 156 ARG A C 1 ATOM 994 O O . ARG A 1 129 ? -72.876 -15.063 13.664 1.00 4.29 ? 156 ARG A O 1 ATOM 995 C CB . ARG A 1 129 ? -70.075 -15.455 12.506 1.00 7.98 ? 156 ARG A CB 1 ATOM 996 C CG . ARG A 1 129 ? -70.065 -16.798 13.220 1.00 8.33 ? 156 ARG A CG 1 ATOM 997 C CD . ARG A 1 129 ? -68.663 -17.289 13.513 1.00 13.25 ? 156 ARG A CD 1 ATOM 998 N NE . ARG A 1 129 ? -68.019 -16.659 14.666 1.00 19.03 ? 156 ARG A NE 1 ATOM 999 C CZ . ARG A 1 129 ? -68.232 -17.022 15.929 1.00 21.10 ? 156 ARG A CZ 1 ATOM 1000 N NH1 . ARG A 1 129 ? -69.104 -17.987 16.208 1.00 19.01 1 156 ARG A NH1 1 ATOM 1001 N NH2 . ARG A 1 129 ? -67.590 -16.407 16.917 1.00 17.67 ? 156 ARG A NH2 1 ATOM 1002 N N . PHE A 1 130 ? -73.121 -16.773 12.231 1.00 3.85 ? 157 PHE A N 1 ATOM 1003 C CA . PHE A 1 130 ? -74.220 -17.391 12.951 1.00 3.74 ? 157 PHE A CA 1 ATOM 1004 C C . PHE A 1 130 ? -73.840 -18.832 13.230 1.00 4.32 ? 157 PHE A C 1 ATOM 1005 O O . PHE A 1 130 ? -73.586 -19.600 12.306 1.00 4.30 ? 157 PHE A O 1 ATOM 1006 C CB . PHE A 1 130 ? -75.509 -17.319 12.121 1.00 3.73 ? 157 PHE A CB 1 ATOM 1007 C CG . PHE A 1 130 ? -76.686 -18.003 12.760 1.00 3.70 ? 157 PHE A CG 1 ATOM 1008 C CD1 . PHE A 1 130 ? -77.384 -17.396 13.789 1.00 3.89 ? 157 PHE A CD1 1 ATOM 1009 C CD2 . PHE A 1 130 ? -77.093 -19.251 12.329 1.00 3.53 ? 157 PHE A CD2 1 ATOM 1010 C CE1 . PHE A 1 130 ? -78.454 -18.025 14.383 1.00 3.88 ? 157 PHE A CE1 1 ATOM 1011 C CE2 . PHE A 1 130 ? -78.161 -19.876 12.918 1.00 4.45 ? 157 PHE A CE2 1 ATOM 1012 C CZ . PHE A 1 130 ? -78.843 -19.263 13.947 1.00 3.94 ? 157 PHE A CZ 1 ATOM 1013 N N . THR A 1 131 ? -73.778 -19.201 14.501 1.00 4.00 ? 158 THR A N 1 ATOM 1014 C CA . THR A 1 131 ? -73.340 -20.542 14.854 1.00 6.08 ? 158 THR A CA 1 ATOM 1015 C C . THR A 1 131 ? -74.283 -21.137 15.873 1.00 4.92 ? 158 THR A C 1 ATOM 1016 O O . THR A 1 131 ? -74.615 -20.491 16.855 1.00 5.55 ? 158 THR A O 1 ATOM 1017 C CB . THR A 1 131 ? -71.907 -20.538 15.438 1.00 9.37 ? 158 THR A CB 1 ATOM 1018 O OG1 . THR A 1 131 ? -70.943 -20.344 14.389 1.00 10.20 ? 158 THR A OG1 1 ATOM 1019 C CG2 . THR A 1 131 ? -71.614 -21.849 16.147 1.00 11.27 ? 158 THR A CG2 1 ATOM 1020 N N . THR A 1 132 ? -74.719 -22.366 15.635 1.00 4.73 ? 159 THR A N 1 ATOM 1021 C CA . THR A 1 132 ? -75.584 -23.052 16.578 1.00 5.64 ? 159 THR A CA 1 ATOM 1022 C C . THR A 1 132 ? -75.511 -24.552 16.379 1.00 8.20 ? 159 THR A C 1 ATOM 1023 O O . THR A 1 132 ? -75.460 -25.030 15.249 1.00 10.11 ? 159 THR A O 1 ATOM 1024 C CB . THR A 1 132 ? -77.046 -22.594 16.442 1.00 8.88 ? 159 THR A CB 1 ATOM 1025 O OG1 . THR A 1 132 ? -77.898 -23.471 17.189 1.00 12.20 ? 159 THR A OG1 1 ATOM 1026 C CG2 . THR A 1 132 ? -77.482 -22.608 14.991 1.00 14.06 ? 159 THR A CG2 1 ATOM 1027 N N . ARG A 1 133 ? -75.500 -25.294 17.482 1.00 9.99 ? 160 ARG A N 1 ATOM 1028 C CA . ARG A 1 133 ? -75.512 -26.751 17.419 1.00 13.88 ? 160 ARG A CA 1 ATOM 1029 C C . ARG A 1 133 ? -76.900 -27.325 17.698 1.00 16.35 ? 160 ARG A C 1 ATOM 1030 O O . ARG A 1 133 ? -77.059 -28.527 17.943 1.00 17.21 ? 160 ARG A O 1 ATOM 1031 C CB . ARG A 1 133 ? -74.472 -27.343 18.360 1.00 15.98 ? 160 ARG A CB 1 ATOM 1032 C CG . ARG A 1 133 ? -73.050 -27.178 17.859 1.00 23.71 ? 160 ARG A CG 1 ATOM 1033 C CD . ARG A 1 133 ? -72.073 -27.216 19.013 1.00 31.65 ? 160 ARG A CD 1 ATOM 1034 N NE . ARG A 1 133 ? -72.363 -26.148 19.966 1.00 35.78 ? 160 ARG A NE 1 ATOM 1035 C CZ . ARG A 1 133 ? -71.728 -25.976 21.119 1.00 33.38 ? 160 ARG A CZ 1 ATOM 1036 N NH1 . ARG A 1 133 ? -70.757 -26.806 21.477 1.00 38.73 1 160 ARG A NH1 1 ATOM 1037 N NH2 . ARG A 1 133 ? -72.067 -24.972 21.914 1.00 34.94 ? 160 ARG A NH2 1 ATOM 1038 N N . ARG A 1 134 ? -77.899 -26.450 17.658 1.00 14.16 ? 161 ARG A N 1 ATOM 1039 C CA . ARG A 1 134 ? -79.286 -26.870 17.647 1.00 14.42 ? 161 ARG A CA 1 ATOM 1040 C C . ARG A 1 134 ? -79.597 -27.442 16.276 1.00 21.72 ? 161 ARG A C 1 ATOM 1041 O O . ARG A 1 134 ? -78.876 -27.170 15.307 1.00 22.17 ? 161 ARG A O 1 ATOM 1042 C CB . ARG A 1 134 ? -80.200 -25.679 17.905 1.00 11.82 ? 161 ARG A CB 1 ATOM 1043 C CG . ARG A 1 134 ? -80.255 -25.225 19.347 1.00 14.37 ? 161 ARG A CG 1 ATOM 1044 C CD . ARG A 1 134 ? -81.193 -26.086 20.188 1.00 17.26 ? 161 ARG A CD 1 ATOM 1045 N NE . ARG A 1 134 ? -80.651 -27.415 20.456 1.00 16.90 ? 161 ARG A NE 1 ATOM 1046 C CZ . ARG A 1 134 ? -79.818 -27.697 21.453 1.00 18.97 ? 161 ARG A CZ 1 ATOM 1047 N NH1 . ARG A 1 134 ? -79.420 -26.742 22.288 1.00 13.40 1 161 ARG A NH1 1 ATOM 1048 N NH2 . ARG A 1 134 ? -79.381 -28.938 21.614 1.00 22.72 ? 161 ARG A NH2 1 ATOM 1049 N N . LEU A 1 135 ? -80.653 -28.247 16.192 1.00 17.50 ? 162 LEU A N 1 ATOM 1050 C CA . LEU A 1 135 ? -81.180 -28.627 14.896 1.00 12.62 ? 162 LEU A CA 1 ATOM 1051 C C . LEU A 1 135 ? -81.997 -27.444 14.455 1.00 13.10 ? 162 LEU A C 1 ATOM 1052 O O . LEU A 1 135 ? -82.991 -27.104 15.089 1.00 20.89 ? 162 LEU A O 1 ATOM 1053 C CB . LEU A 1 135 ? -82.075 -29.850 14.999 1.00 16.24 ? 162 LEU A CB 1 ATOM 1054 C CG . LEU A 1 135 ? -82.714 -30.264 13.676 1.00 13.64 ? 162 LEU A CG 1 ATOM 1055 C CD1 . LEU A 1 135 ? -81.633 -30.661 12.692 1.00 19.13 ? 162 LEU A CD1 1 ATOM 1056 C CD2 . LEU A 1 135 ? -83.698 -31.393 13.876 1.00 11.15 ? 162 LEU A CD2 1 ATOM 1057 N N . THR A 1 136 ? -81.570 -26.792 13.386 1.00 12.48 ? 163 THR A N 1 ATOM 1058 C CA . THR A 1 136 ? -82.236 -25.575 12.961 1.00 13.29 ? 163 THR A CA 1 ATOM 1059 C C . THR A 1 136 ? -82.135 -25.400 11.462 1.00 13.11 ? 163 THR A C 1 ATOM 1060 O O . THR A 1 136 ? -81.140 -25.773 10.848 1.00 14.50 ? 163 THR A O 1 ATOM 1061 C CB . THR A 1 136 ? -81.693 -24.338 13.719 1.00 14.03 ? 163 THR A CB 1 ATOM 1062 O OG1 . THR A 1 136 ? -82.640 -23.946 14.725 1.00 15.98 ? 163 THR A OG1 1 ATOM 1063 C CG2 . THR A 1 136 ? -81.441 -23.166 12.776 1.00 10.73 ? 163 THR A CG2 1 ATOM 1064 N N . HIS A 1 137 ? -83.197 -24.863 10.877 1.00 17.12 ? 164 HIS A N 1 ATOM 1065 C CA . HIS A 1 137 ? -83.231 -24.582 9.456 1.00 18.32 ? 164 HIS A CA 1 ATOM 1066 C C . HIS A 1 137 ? -82.877 -23.121 9.198 1.00 15.17 ? 164 HIS A C 1 ATOM 1067 O O . HIS A 1 137 ? -83.320 -22.228 9.918 1.00 15.69 ? 164 HIS A O 1 ATOM 1068 C CB . HIS A 1 137 ? -84.620 -24.893 8.903 1.00 24.27 ? 164 HIS A CB 1 ATOM 1069 C CG . HIS A 1 137 ? -84.790 -24.523 7.464 1.00 25.90 ? 164 HIS A CG 1 ATOM 1070 N ND1 . HIS A 1 137 ? -84.269 -25.280 6.436 1.00 23.42 ? 164 HIS A ND1 1 ATOM 1071 C CD2 . HIS A 1 137 ? -85.414 -23.472 6.881 1.00 21.04 ? 164 HIS A CD2 1 ATOM 1072 C CE1 . HIS A 1 137 ? -84.570 -24.713 5.282 1.00 22.63 ? 164 HIS A CE1 1 ATOM 1073 N NE2 . HIS A 1 137 ? -85.265 -23.615 5.524 1.00 21.44 ? 164 HIS A NE2 1 ATOM 1074 N N . ILE A 1 138 ? -82.067 -22.885 8.172 1.00 13.24 ? 165 ILE A N 1 ATOM 1075 C CA . ILE A 1 138 ? -81.715 -21.526 7.773 1.00 15.74 ? 165 ILE A CA 1 ATOM 1076 C C . ILE A 1 138 ? -82.421 -21.136 6.470 1.00 15.35 ? 165 ILE A C 1 ATOM 1077 O O . ILE A 1 138 ? -82.232 -21.779 5.437 1.00 18.54 ? 165 ILE A O 1 ATOM 1078 C CB . ILE A 1 138 ? -80.176 -21.350 7.649 1.00 12.74 ? 165 ILE A CB 1 ATOM 1079 C CG1 . ILE A 1 138 ? -79.534 -21.389 9.040 1.00 9.95 ? 165 ILE A CG1 1 ATOM 1080 C CG2 . ILE A 1 138 ? -79.830 -20.044 6.944 1.00 8.86 ? 165 ILE A CG2 1 ATOM 1081 C CD1 . ILE A 1 138 ? -78.020 -21.424 9.039 1.00 6.56 ? 165 ILE A CD1 1 ATOM 1082 N N . PRO A 1 139 ? -83.253 -20.085 6.522 1.00 10.55 ? 166 PRO A N 1 ATOM 1083 C CA . PRO A 1 139 ? -84.006 -19.610 5.359 1.00 12.62 ? 166 PRO A CA 1 ATOM 1084 C C . PRO A 1 139 ? -83.091 -19.041 4.287 1.00 10.71 ? 166 PRO A C 1 ATOM 1085 O O . PRO A 1 139 ? -82.117 -18.387 4.616 1.00 12.16 ? 166 PRO A O 1 ATOM 1086 C CB . PRO A 1 139 ? -84.880 -18.495 5.942 1.00 12.38 ? 166 PRO A CB 1 ATOM 1087 C CG . PRO A 1 139 ? -84.157 -18.041 7.141 1.00 11.19 ? 166 PRO A CG 1 ATOM 1088 C CD . PRO A 1 139 ? -83.520 -19.270 7.715 1.00 10.37 ? 166 PRO A CD 1 ATOM 1089 N N . ALA A 1 140 ? -83.405 -19.283 3.022 1.00 10.83 ? 167 ALA A N 1 ATOM 1090 C CA . ALA A 1 140 ? -82.582 -18.780 1.934 1.00 11.32 ? 167 ALA A CA 1 ATOM 1091 C C . ALA A 1 140 ? -82.892 -17.321 1.609 1.00 11.93 ? 167 ALA A C 1 ATOM 1092 O O . ALA A 1 140 ? -82.243 -16.712 0.755 1.00 11.11 ? 167 ALA A O 1 ATOM 1093 C CB . ALA A 1 140 ? -82.758 -19.633 0.718 1.00 12.81 ? 167 ALA A CB 1 ATOM 1094 N N . ASN A 1 141 ? -83.888 -16.765 2.287 1.00 11.45 ? 168 ASN A N 1 ATOM 1095 C CA . ASN A 1 141 ? -84.201 -15.355 2.129 1.00 11.12 ? 168 ASN A CA 1 ATOM 1096 C C . ASN A 1 141 ? -83.546 -14.558 3.247 1.00 11.82 ? 168 ASN A C 1 ATOM 1097 O O . ASN A 1 141 ? -83.831 -13.378 3.442 1.00 12.05 ? 168 ASN A O 1 ATOM 1098 C CB . ASN A 1 141 ? -85.718 -15.130 2.091 1.00 11.87 ? 168 ASN A CB 1 ATOM 1099 C CG . ASN A 1 141 ? -86.336 -14.989 3.471 1.00 14.52 ? 168 ASN A CG 1 ATOM 1100 O OD1 . ASN A 1 141 ? -85.977 -15.698 4.411 1.00 12.20 ? 168 ASN A OD1 1 ATOM 1101 N ND2 . ASN A 1 141 ? -87.283 -14.066 3.593 1.00 17.76 ? 168 ASN A ND2 1 ATOM 1102 N N . LEU A 1 142 ? -82.649 -15.228 3.966 1.00 10.71 ? 169 LEU A N 1 ATOM 1103 C CA . LEU A 1 142 ? -82.048 -14.692 5.179 1.00 8.20 ? 169 LEU A CA 1 ATOM 1104 C C . LEU A 1 142 ? -81.134 -13.522 4.899 1.00 8.75 ? 169 LEU A C 1 ATOM 1105 O O . LEU A 1 142 ? -81.193 -12.500 5.579 1.00 10.68 ? 169 LEU A O 1 ATOM 1106 C CB . LEU A 1 142 ? -81.254 -15.780 5.893 1.00 7.84 ? 169 LEU A CB 1 ATOM 1107 C CG . LEU A 1 142 ? -80.622 -15.402 7.224 1.00 8.26 ? 169 LEU A CG 1 ATOM 1108 C CD1 . LEU A 1 142 ? -81.693 -14.896 8.158 1.00 7.32 ? 169 LEU A CD1 1 ATOM 1109 C CD2 . LEU A 1 142 ? -79.903 -16.597 7.819 1.00 6.73 ? 169 LEU A CD2 1 ATOM 1110 N N . LEU A 1 143 ? -80.278 -13.677 3.901 1.00 8.44 ? 170 LEU A N 1 ATOM 1111 C CA . LEU A 1 143 ? -79.299 -12.652 3.596 1.00 9.84 ? 170 LEU A CA 1 ATOM 1112 C C . LEU A 1 143 ? -79.792 -11.797 2.456 1.00 11.75 ? 170 LEU A C 1 ATOM 1113 O O . LEU A 1 143 ? -79.167 -11.721 1.397 1.00 15.59 ? 170 LEU A O 1 ATOM 1114 C CB . LEU A 1 143 ? -77.962 -13.287 3.244 1.00 13.01 ? 170 LEU A CB 1 ATOM 1115 C CG . LEU A 1 143 ? -77.325 -14.095 4.369 1.00 8.19 ? 170 LEU A CG 1 ATOM 1116 C CD1 . LEU A 1 143 ? -75.982 -14.621 3.907 1.00 7.46 ? 170 LEU A CD1 1 ATOM 1117 C CD2 . LEU A 1 143 ? -77.186 -13.236 5.614 1.00 6.92 ? 170 LEU A CD2 1 ATOM 1118 N N . THR A 1 144 ? -80.932 -11.163 2.683 1.00 12.38 ? 171 THR A N 1 ATOM 1119 C CA . THR A 1 144 ? -81.535 -10.299 1.690 1.00 15.40 ? 171 THR A CA 1 ATOM 1120 C C . THR A 1 144 ? -81.058 -8.882 1.927 1.00 17.40 ? 171 THR A C 1 ATOM 1121 O O . THR A 1 144 ? -81.058 -8.402 3.061 1.00 17.46 ? 171 THR A O 1 ATOM 1122 C CB . THR A 1 144 ? -83.067 -10.348 1.768 1.00 15.51 ? 171 THR A CB 1 ATOM 1123 O OG1 . THR A 1 144 ? -83.510 -11.703 1.638 1.00 12.59 ? 171 THR A OG1 1 ATOM 1124 C CG2 . THR A 1 144 ? -83.685 -9.516 0.663 1.00 24.34 ? 171 THR A CG2 1 ATOM 1125 N N . ASP A 1 145 ? -80.637 -8.229 0.849 1.00 19.38 ? 172 ASP A N 1 ATOM 1126 C CA . ASP A 1 145 ? -80.177 -6.845 0.892 1.00 24.21 ? 172 ASP A CA 1 ATOM 1127 C C . ASP A 1 145 ? -78.901 -6.707 1.713 1.00 24.74 ? 172 ASP A C 1 ATOM 1128 O O . ASP A 1 145 ? -78.637 -5.654 2.292 1.00 26.42 ? 172 ASP A O 1 ATOM 1129 C CB . ASP A 1 145 ? -81.269 -5.906 1.429 1.00 24.16 ? 172 ASP A CB 1 ATOM 1130 C CG . ASP A 1 145 ? -82.612 -6.093 0.725 1.00 26.69 ? 172 ASP A CG 1 ATOM 1131 O OD1 . ASP A 1 145 ? -82.633 -6.534 -0.447 1.00 25.73 ? 172 ASP A OD1 1 ATOM 1132 O OD2 . ASP A 1 145 ? -83.653 -5.795 1.346 1.00 24.83 1 172 ASP A OD2 1 ATOM 1133 N N . MET A 1 146 ? -78.113 -7.778 1.758 1.00 20.66 ? 173 MET A N 1 ATOM 1134 C CA . MET A 1 146 ? -76.825 -7.755 2.440 1.00 19.00 ? 173 MET A CA 1 ATOM 1135 C C . MET A 1 146 ? -75.711 -7.408 1.458 1.00 26.89 ? 173 MET A C 1 ATOM 1136 O O . MET A 1 146 ? -74.822 -8.221 1.196 1.00 24.79 ? 173 MET A O 1 ATOM 1137 C CB . MET A 1 146 ? -76.545 -9.106 3.086 1.00 16.32 ? 173 MET A CB 1 ATOM 1138 C CG . MET A 1 146 ? -77.380 -9.405 4.318 1.00 15.62 ? 173 MET A CG 1 ATOM 1139 S SD . MET A 1 146 ? -77.100 -8.203 5.629 1.00 14.36 ? 173 MET A SD 1 ATOM 1140 C CE . MET A 1 146 ? -77.781 -9.060 7.042 1.00 11.09 ? 173 MET A CE 1 ATOM 1141 N N . ARG A 1 147 ? -75.768 -6.192 0.921 1.00 32.24 ? 174 ARG A N 1 ATOM 1142 C CA . ARG A 1 147 ? -74.845 -5.751 -0.124 1.00 27.61 ? 174 ARG A CA 1 ATOM 1143 C C . ARG A 1 147 ? -73.412 -5.534 0.381 1.00 27.32 ? 174 ARG A C 1 ATOM 1144 O O . ARG A 1 147 ? -72.474 -5.450 -0.411 1.00 24.59 ? 174 ARG A O 1 ATOM 1145 C CB . ARG A 1 147 ? -75.368 -4.465 -0.780 1.00 30.19 ? 174 ARG A CB 1 ATOM 1146 C CG . ARG A 1 147 ? -76.678 -4.623 -1.541 1.00 28.83 ? 174 ARG A CG 1 ATOM 1147 C CD . ARG A 1 147 ? -76.508 -5.507 -2.761 1.00 32.17 ? 174 ARG A CD 1 ATOM 1148 N NE . ARG A 1 147 ? -77.787 -5.832 -3.387 1.00 39.53 ? 174 ARG A NE 1 ATOM 1149 C CZ . ARG A 1 147 ? -77.924 -6.635 -4.440 1.00 36.80 ? 174 ARG A CZ 1 ATOM 1150 N NH1 . ARG A 1 147 ? -76.856 -7.201 -4.994 1.00 29.08 1 174 ARG A NH1 1 ATOM 1151 N NH2 . ARG A 1 147 ? -79.131 -6.873 -4.940 1.00 32.91 ? 174 ARG A NH2 1 ATOM 1152 N N . ASN A 1 148 ? -73.246 -5.450 1.697 1.00 26.20 ? 175 ASN A N 1 ATOM 1153 C CA . ASN A 1 148 ? -71.954 -5.108 2.275 1.00 24.01 ? 175 ASN A CA 1 ATOM 1154 C C . ASN A 1 148 ? -71.234 -6.271 2.934 1.00 19.22 ? 175 ASN A C 1 ATOM 1155 O O . ASN A 1 148 ? -70.031 -6.196 3.196 1.00 15.72 ? 175 ASN A O 1 ATOM 1156 C CB . ASN A 1 148 ? -72.114 -3.975 3.274 1.00 26.61 ? 175 ASN A CB 1 ATOM 1157 C CG . ASN A 1 148 ? -72.611 -2.715 2.632 1.00 38.49 ? 175 ASN A CG 1 ATOM 1158 O OD1 . ASN A 1 148 ? -72.553 -2.559 1.408 1.00 38.32 ? 175 ASN A OD1 1 ATOM 1159 N ND2 . ASN A 1 148 ? -73.106 -1.796 3.454 1.00 46.01 ? 175 ASN A ND2 1 ATOM 1160 N N . LEU A 1 149 ? -71.978 -7.332 3.217 1.00 16.27 ? 176 LEU A N 1 ATOM 1161 C CA . LEU A 1 149 ? -71.382 -8.544 3.741 1.00 12.49 ? 176 LEU A CA 1 ATOM 1162 C C . LEU A 1 149 ? -70.161 -8.893 2.908 1.00 13.69 ? 176 LEU A C 1 ATOM 1163 O O . LEU A 1 149 ? -70.266 -9.083 1.699 1.00 16.26 ? 176 LEU A O 1 ATOM 1164 C CB . LEU A 1 149 ? -72.386 -9.684 3.681 1.00 11.06 ? 176 LEU A CB 1 ATOM 1165 C CG . LEU A 1 149 ? -72.555 -10.418 5.002 1.00 10.25 ? 176 LEU A CG 1 ATOM 1166 C CD1 . LEU A 1 149 ? -73.055 -9.451 6.062 1.00 11.36 ? 176 LEU A CD1 1 ATOM 1167 C CD2 . LEU A 1 149 ? -73.495 -11.599 4.841 1.00 9.78 ? 176 LEU A CD2 1 ATOM 1168 N N . SER A 1 150 ? -68.996 -8.927 3.549 1.00 13.34 ? 177 SER A N 1 ATOM 1169 C CA . SER A 1 150 ? -67.765 -9.304 2.865 1.00 12.43 ? 177 SER A CA 1 ATOM 1170 C C . SER A 1 150 ? -67.263 -10.630 3.395 1.00 9.80 ? 177 SER A C 1 ATOM 1171 O O . SER A 1 150 ? -66.549 -11.353 2.700 1.00 9.67 ? 177 SER A O 1 ATOM 1172 C CB . SER A 1 150 ? -66.694 -8.241 3.059 1.00 12.90 ? 177 SER A CB 1 ATOM 1173 O OG . SER A 1 150 ? -66.400 -8.088 4.431 1.00 14.39 ? 177 SER A OG 1 ATOM 1174 N N . HIS A 1 151 ? -67.640 -10.938 4.632 1.00 8.50 ? 178 HIS A N 1 ATOM 1175 C CA . HIS A 1 151 ? -67.290 -12.209 5.252 1.00 10.35 ? 178 HIS A CA 1 ATOM 1176 C C . HIS A 1 151 ? -68.516 -12.871 5.858 1.00 7.50 ? 178 HIS A C 1 ATOM 1177 O O . HIS A 1 151 ? -69.159 -12.313 6.741 1.00 7.88 ? 178 HIS A O 1 ATOM 1178 C CB . HIS A 1 151 ? -66.211 -12.020 6.332 1.00 15.93 ? 178 HIS A CB 1 ATOM 1179 C CG . HIS A 1 151 ? -65.861 -13.282 7.066 1.00 16.08 ? 178 HIS A CG 1 ATOM 1180 N ND1 . HIS A 1 151 ? -64.995 -14.227 6.556 1.00 11.02 ? 178 HIS A ND1 1 ATOM 1181 C CD2 . HIS A 1 151 ? -66.273 -13.761 8.265 1.00 15.95 ? 178 HIS A CD2 1 ATOM 1182 C CE1 . HIS A 1 151 ? -64.884 -15.229 7.410 1.00 9.41 ? 178 HIS A CE1 1 ATOM 1183 N NE2 . HIS A 1 151 ? -65.651 -14.972 8.454 1.00 12.67 ? 178 HIS A NE2 1 ATOM 1184 N N . LEU A 1 152 ? -68.827 -14.071 5.387 1.00 6.31 ? 179 LEU A N 1 ATOM 1185 C CA . LEU A 1 152 ? -69.955 -14.828 5.910 1.00 7.08 ? 179 LEU A CA 1 ATOM 1186 C C . LEU A 1 152 ? -69.506 -16.150 6.528 1.00 7.81 ? 179 LEU A C 1 ATOM 1187 O O . LEU A 1 152 ? -68.612 -16.813 6.008 1.00 10.43 ? 179 LEU A O 1 ATOM 1188 C CB . LEU A 1 152 ? -70.963 -15.102 4.792 1.00 8.26 ? 179 LEU A CB 1 ATOM 1189 C CG . LEU A 1 152 ? -72.150 -16.015 5.115 1.00 7.24 ? 179 LEU A CG 1 ATOM 1190 C CD1 . LEU A 1 152 ? -73.111 -15.340 6.081 1.00 6.01 ? 179 LEU A CD1 1 ATOM 1191 C CD2 . LEU A 1 152 ? -72.859 -16.433 3.837 1.00 8.47 ? 179 LEU A CD2 1 ATOM 1192 N N . GLU A 1 153 ? -70.122 -16.532 7.638 1.00 5.37 ? 180 GLU A N 1 ATOM 1193 C CA . GLU A 1 153 ? -69.877 -17.842 8.216 1.00 5.79 ? 180 GLU A CA 1 ATOM 1194 C C . GLU A 1 153 ? -71.103 -18.319 8.961 1.00 6.36 ? 180 GLU A C 1 ATOM 1195 O O . GLU A 1 153 ? -71.574 -17.665 9.889 1.00 6.73 ? 180 GLU A O 1 ATOM 1196 C CB . GLU A 1 153 ? -68.681 -17.819 9.165 1.00 9.17 ? 180 GLU A CB 1 ATOM 1197 C CG . GLU A 1 153 ? -68.462 -19.146 9.887 1.00 11.08 ? 180 GLU A CG 1 ATOM 1198 C CD . GLU A 1 153 ? -67.472 -19.045 11.042 1.00 14.69 ? 180 GLU A CD 1 ATOM 1199 O OE1 . GLU A 1 153 ? -66.794 -17.999 11.160 1.00 12.04 ? 180 GLU A OE1 1 ATOM 1200 O OE2 . GLU A 1 153 ? -67.390 -20.006 11.842 1.00 15.63 1 180 GLU A OE2 1 ATOM 1201 N N . LEU A 1 154 ? -71.620 -19.467 8.552 1.00 5.92 ? 181 LEU A N 1 ATOM 1202 C CA . LEU A 1 154 ? -72.780 -20.044 9.200 1.00 5.54 ? 181 LEU A CA 1 ATOM 1203 C C . LEU A 1 154 ? -72.433 -21.472 9.577 1.00 5.13 ? 181 LEU A C 1 ATOM 1204 O O . LEU A 1 154 ? -71.784 -22.177 8.809 1.00 6.32 ? 181 LEU A O 1 ATOM 1205 C CB . LEU A 1 154 ? -73.983 -20.026 8.249 1.00 6.39 ? 181 LEU A CB 1 ATOM 1206 C CG . LEU A 1 154 ? -74.294 -18.742 7.466 1.00 5.19 ? 181 LEU A CG 1 ATOM 1207 C CD1 . LEU A 1 154 ? -75.241 -19.049 6.320 1.00 3.75 ? 181 LEU A CD1 1 ATOM 1208 C CD2 . LEU A 1 154 ? -74.864 -17.644 8.366 1.00 3.01 ? 181 LEU A CD2 1 ATOM 1209 N N . ARG A 1 155 ? -72.854 -21.901 10.757 1.00 5.04 ? 182 ARG A N 1 ATOM 1210 C CA . ARG A 1 155 ? -72.629 -23.276 11.164 1.00 6.90 ? 182 ARG A CA 1 ATOM 1211 C C . ARG A 1 155 ? -73.809 -23.816 11.941 1.00 7.49 ? 182 ARG A C 1 ATOM 1212 O O . ARG A 1 155 ? -73.876 -23.658 13.157 1.00 7.91 ? 182 ARG A O 1 ATOM 1213 C CB . ARG A 1 155 ? -71.377 -23.372 12.020 1.00 10.39 ? 182 ARG A CB 1 ATOM 1214 C CG . ARG A 1 155 ? -70.975 -24.788 12.367 1.00 12.12 ? 182 ARG A CG 1 ATOM 1215 C CD . ARG A 1 155 ? -69.967 -24.762 13.496 1.00 19.98 ? 182 ARG A CD 1 ATOM 1216 N NE . ARG A 1 155 ? -69.098 -23.593 13.396 1.00 24.32 ? 182 ARG A NE 1 ATOM 1217 C CZ . ARG A 1 155 ? -67.771 -23.635 13.427 1.00 26.37 ? 182 ARG A CZ 1 ATOM 1218 N NH1 . ARG A 1 155 ? -67.140 -24.797 13.560 1.00 17.62 1 182 ARG A NH1 1 ATOM 1219 N NH2 . ARG A 1 155 ? -67.079 -22.507 13.328 1.00 26.10 ? 182 ARG A NH2 1 ATOM 1220 N N . ALA A 1 156 ? -74.735 -24.457 11.239 1.00 8.51 ? 183 ALA A N 1 ATOM 1221 C CA . ALA A 1 156 ? -75.940 -24.979 11.874 1.00 12.06 ? 183 ALA A CA 1 ATOM 1222 C C . ALA A 1 156 ? -76.268 -26.376 11.377 1.00 14.13 ? 183 ALA A C 1 ATOM 1223 O O . ALA A 1 156 ? -77.440 -26.734 11.263 1.00 16.30 ? 183 ALA A O 1 ATOM 1224 C CB . ALA A 1 156 ? -77.121 -24.044 11.634 1.00 9.22 ? 183 ALA A CB 1 ATOM 1225 N N . ASN A 1 157 ? -75.229 -27.160 11.098 1.00 15.07 ? 184 ASN A N 1 ATOM 1226 C CA . ASN A 1 157 ? -75.395 -28.492 10.527 1.00 15.78 ? 184 ASN A CA 1 ATOM 1227 C C . ASN A 1 157 ? -76.170 -28.404 9.221 1.00 15.36 ? 184 ASN A C 1 ATOM 1228 O O . ASN A 1 157 ? -77.071 -29.204 8.966 1.00 16.27 ? 184 ASN A O 1 ATOM 1229 C CB . ASN A 1 157 ? -76.103 -29.439 11.504 1.00 16.86 ? 184 ASN A CB 1 ATOM 1230 C CG . ASN A 1 157 ? -75.207 -29.884 12.648 1.00 16.70 ? 184 ASN A CG 1 ATOM 1231 O OD1 . ASN A 1 157 ? -74.316 -30.707 12.460 1.00 15.07 ? 184 ASN A OD1 1 ATOM 1232 N ND2 . ASN A 1 157 ? -75.462 -29.361 13.847 1.00 15.62 ? 184 ASN A ND2 1 ATOM 1233 N N . ILE A 1 158 ? -75.813 -27.415 8.408 1.00 11.23 ? 185 ILE A N 1 ATOM 1234 C CA . ILE A 1 158 ? -76.510 -27.134 7.161 1.00 11.50 ? 185 ILE A CA 1 ATOM 1235 C C . ILE A 1 158 ? -76.368 -28.253 6.141 1.00 13.84 ? 185 ILE A C 1 ATOM 1236 O O . ILE A 1 158 ? -75.258 -28.578 5.727 1.00 13.80 ? 185 ILE A O 1 ATOM 1237 C CB . ILE A 1 158 ? -75.979 -25.854 6.531 1.00 11.43 ? 185 ILE A CB 1 ATOM 1238 C CG1 . ILE A 1 158 ? -76.152 -24.685 7.504 1.00 12.03 ? 185 ILE A CG1 1 ATOM 1239 C CG2 . ILE A 1 158 ? -76.673 -25.598 5.206 1.00 14.58 ? 185 ILE A CG2 1 ATOM 1240 C CD1 . ILE A 1 158 ? -75.728 -23.341 6.940 1.00 9.56 ? 185 ILE A CD1 1 ATOM 1241 N N . GLU A 1 159 ? -77.498 -28.819 5.719 1.00 18.17 ? 186 GLU A N 1 ATOM 1242 C CA . GLU A 1 159 ? -77.504 -29.982 4.825 1.00 17.26 ? 186 GLU A CA 1 ATOM 1243 C C . GLU A 1 159 ? -77.403 -29.626 3.345 1.00 13.88 ? 186 GLU A C 1 ATOM 1244 O O . GLU A 1 159 ? -76.883 -30.409 2.548 1.00 12.68 ? 186 GLU A O 1 ATOM 1245 C CB . GLU A 1 159 ? -78.737 -30.855 5.079 1.00 14.78 ? 186 GLU A CB 1 ATOM 1246 C CG . GLU A 1 159 ? -78.557 -31.839 6.219 1.00 18.32 ? 186 GLU A CG 1 ATOM 1247 C CD . GLU A 1 159 ? -79.854 -32.485 6.648 1.00 22.73 ? 186 GLU A CD 1 ATOM 1248 O OE1 . GLU A 1 159 ? -79.811 -33.567 7.276 1.00 20.48 ? 186 GLU A OE1 1 ATOM 1249 O OE2 . GLU A 1 159 ? -80.917 -31.901 6.362 1.00 28.12 1 186 GLU A OE2 1 ATOM 1250 N N . GLU A 1 160 ? -77.907 -28.450 2.986 1.00 14.12 ? 187 GLU A N 1 ATOM 1251 C CA . GLU A 1 160 ? -77.844 -27.970 1.609 1.00 18.06 ? 187 GLU A CA 1 ATOM 1252 C C . GLU A 1 160 ? -78.304 -26.528 1.511 1.00 20.06 ? 187 GLU A C 1 ATOM 1253 O O . GLU A 1 160 ? -79.248 -26.121 2.187 1.00 20.77 ? 187 GLU A O 1 ATOM 1254 C CB . GLU A 1 160 ? -78.694 -28.836 0.683 1.00 20.67 ? 187 GLU A CB 1 ATOM 1255 C CG . GLU A 1 160 ? -80.154 -28.947 1.069 1.00 16.71 ? 187 GLU A CG 1 ATOM 1256 C CD . GLU A 1 160 ? -80.914 -29.822 0.098 1.00 32.86 ? 187 GLU A CD 1 ATOM 1257 O OE1 . GLU A 1 160 ? -80.755 -29.610 -1.125 1.00 39.44 ? 187 GLU A OE1 1 ATOM 1258 O OE2 . GLU A 1 160 ? -81.650 -30.730 0.550 1.00 37.35 1 187 GLU A OE2 1 ATOM 1259 N N . MET A 1 161 ? -77.641 -25.757 0.659 1.00 17.05 ? 188 MET A N 1 ATOM 1260 C CA . MET A 1 161 ? -77.971 -24.350 0.537 1.00 19.76 ? 188 MET A CA 1 ATOM 1261 C C . MET A 1 161 ? -78.305 -23.977 -0.898 1.00 17.95 ? 188 MET A C 1 ATOM 1262 O O . MET A 1 161 ? -77.496 -24.180 -1.799 1.00 21.61 ? 188 MET A O 1 ATOM 1263 C CB . MET A 1 161 ? -76.832 -23.483 1.074 1.00 25.53 ? 188 MET A CB 1 ATOM 1264 C CG . MET A 1 161 ? -77.327 -22.219 1.758 1.00 37.33 ? 188 MET A CG 1 ATOM 1265 S SD . MET A 1 161 ? -78.655 -22.582 2.936 1.00 73.71 ? 188 MET A SD 1 ATOM 1266 C CE . MET A 1 161 ? -79.133 -20.942 3.471 1.00 23.35 ? 188 MET A CE 1 ATOM 1267 N N . PRO A 1 162 ? -79.510 -23.433 -1.109 1.00 16.26 ? 189 PRO A N 1 ATOM 1268 C CA . PRO A 1 162 ? -80.014 -23.036 -2.426 1.00 19.72 ? 189 PRO A CA 1 ATOM 1269 C C . PRO A 1 162 ? -79.428 -21.714 -2.912 1.00 18.34 ? 189 PRO A C 1 ATOM 1270 O O . PRO A 1 162 ? -79.345 -20.747 -2.155 1.00 18.09 ? 189 PRO A O 1 ATOM 1271 C CB . PRO A 1 162 ? -81.518 -22.899 -2.191 1.00 18.44 ? 189 PRO A CB 1 ATOM 1272 C CG . PRO A 1 162 ? -81.627 -22.533 -0.778 1.00 19.29 ? 189 PRO A CG 1 ATOM 1273 C CD . PRO A 1 162 ? -80.512 -23.223 -0.054 1.00 18.52 ? 189 PRO A CD 1 ATOM 1274 N N . SER A 1 163 ? -79.043 -21.695 -4.183 1.00 16.11 ? 190 SER A N 1 ATOM 1275 C CA . SER A 1 163 ? -78.329 -20.578 -4.795 1.00 18.15 ? 190 SER A CA 1 ATOM 1276 C C . SER A 1 163 ? -78.895 -19.191 -4.484 1.00 20.51 ? 190 SER A C 1 ATOM 1277 O O . SER A 1 163 ? -78.142 -18.233 -4.303 1.00 17.25 ? 190 SER A O 1 ATOM 1278 C CB . SER A 1 163 ? -78.254 -20.789 -6.308 1.00 21.54 ? 190 SER A CB 1 ATOM 1279 O OG . SER A 1 163 ? -79.295 -21.649 -6.746 1.00 19.81 ? 190 SER A OG 1 ATOM 1280 N N . HIS A 1 164 ? -80.217 -19.084 -4.395 1.00 23.98 ? 191 HIS A N 1 ATOM 1281 C CA . HIS A 1 164 ? -80.853 -17.781 -4.214 1.00 19.89 ? 191 HIS A CA 1 ATOM 1282 C C . HIS A 1 164 ? -80.654 -17.212 -2.811 1.00 19.53 ? 191 HIS A C 1 ATOM 1283 O O . HIS A 1 164 ? -81.382 -16.311 -2.392 1.00 17.60 ? 191 HIS A O 1 ATOM 1284 C CB . HIS A 1 164 ? -82.339 -17.833 -4.576 1.00 17.07 ? 191 HIS A CB 1 ATOM 1285 C CG . HIS A 1 164 ? -83.179 -18.591 -3.596 1.00 22.78 ? 191 HIS A CG 1 ATOM 1286 N ND1 . HIS A 1 164 ? -83.514 -19.917 -3.772 1.00 26.29 ? 191 HIS A ND1 1 ATOM 1287 C CD2 . HIS A 1 164 ? -83.762 -18.205 -2.435 1.00 18.57 ? 191 HIS A CD2 1 ATOM 1288 C CE1 . HIS A 1 164 ? -84.264 -20.318 -2.760 1.00 23.57 ? 191 HIS A CE1 1 ATOM 1289 N NE2 . HIS A 1 164 ? -84.432 -19.297 -1.936 1.00 21.17 ? 191 HIS A NE2 1 ATOM 1290 N N . LEU A 1 165 ? -79.669 -17.745 -2.092 1.00 20.43 ? 192 LEU A N 1 ATOM 1291 C CA . LEU A 1 165 ? -79.272 -17.191 -0.807 1.00 18.45 ? 192 LEU A CA 1 ATOM 1292 C C . LEU A 1 165 ? -78.298 -16.064 -1.075 1.00 19.43 ? 192 LEU A C 1 ATOM 1293 O O . LEU A 1 165 ? -78.445 -14.951 -0.548 1.00 17.95 ? 192 LEU A O 1 ATOM 1294 C CB . LEU A 1 165 ? -78.595 -18.250 0.057 1.00 14.51 ? 192 LEU A CB 1 ATOM 1295 C CG . LEU A 1 165 ? -78.068 -17.727 1.392 1.00 11.92 ? 192 LEU A CG 1 ATOM 1296 C CD1 . LEU A 1 165 ? -79.169 -17.592 2.412 1.00 8.38 ? 192 LEU A CD1 1 ATOM 1297 C CD2 . LEU A 1 165 ? -76.982 -18.626 1.904 1.00 17.29 ? 192 LEU A CD2 1 ATOM 1298 N N . PHE A 1 166 ? -77.316 -16.364 -1.922 1.00 15.49 ? 193 PHE A N 1 ATOM 1299 C CA . PHE A 1 166 ? -76.265 -15.413 -2.266 1.00 17.44 ? 193 PHE A CA 1 ATOM 1300 C C . PHE A 1 166 ? -76.710 -14.425 -3.340 1.00 19.16 ? 193 PHE A C 1 ATOM 1301 O O . PHE A 1 166 ? -75.974 -14.162 -4.284 1.00 17.16 ? 193 PHE A O 1 ATOM 1302 C CB . PHE A 1 166 ? -75.013 -16.151 -2.751 1.00 14.70 ? 193 PHE A CB 1 ATOM 1303 C CG . PHE A 1 166 ? -74.747 -17.443 -2.029 1.00 16.46 ? 193 PHE A CG 1 ATOM 1304 C CD1 . PHE A 1 166 ? -74.313 -17.445 -0.716 1.00 18.81 ? 193 PHE A CD1 1 ATOM 1305 C CD2 . PHE A 1 166 ? -74.920 -18.657 -2.668 1.00 18.22 ? 193 PHE A CD2 1 ATOM 1306 C CE1 . PHE A 1 166 ? -74.068 -18.634 -0.052 1.00 15.85 ? 193 PHE A CE1 1 ATOM 1307 C CE2 . PHE A 1 166 ? -74.677 -19.847 -2.011 1.00 16.69 ? 193 PHE A CE2 1 ATOM 1308 C CZ . PHE A 1 166 ? -74.251 -19.835 -0.702 1.00 15.42 ? 193 PHE A CZ 1 ATOM 1309 N N . ASP A 1 167 ? -77.907 -13.870 -3.198 1.00 22.53 ? 194 ASP A N 1 ATOM 1310 C CA . ASP A 1 167 ? -78.451 -13.008 -4.239 1.00 21.09 ? 194 ASP A CA 1 ATOM 1311 C C . ASP A 1 167 ? -77.942 -11.580 -4.133 1.00 22.08 ? 194 ASP A C 1 ATOM 1312 O O . ASP A 1 167 ? -77.611 -10.965 -5.142 1.00 24.99 ? 194 ASP A O 1 ATOM 1313 C CB . ASP A 1 167 ? -79.981 -13.044 -4.236 1.00 24.64 ? 194 ASP A CB 1 ATOM 1314 C CG . ASP A 1 167 ? -80.537 -14.245 -4.978 1.00 22.54 ? 194 ASP A CG 1 ATOM 1315 O OD1 . ASP A 1 167 ? -79.731 -15.102 -5.402 1.00 20.56 ? 194 ASP A OD1 1 ATOM 1316 O OD2 . ASP A 1 167 ? -81.776 -14.330 -5.137 1.00 22.02 1 194 ASP A OD2 1 ATOM 1317 N N . ASP A 1 168 ? -77.874 -11.061 -2.912 1.00 23.17 ? 195 ASP A N 1 ATOM 1318 C CA . ASP A 1 168 ? -77.453 -9.679 -2.692 1.00 24.49 ? 195 ASP A CA 1 ATOM 1319 C C . ASP A 1 168 ? -76.061 -9.604 -2.066 1.00 23.99 ? 195 ASP A C 1 ATOM 1320 O O . ASP A 1 168 ? -75.661 -8.565 -1.537 1.00 23.77 ? 195 ASP A O 1 ATOM 1321 C CB . ASP A 1 168 ? -78.468 -8.942 -1.810 1.00 25.91 ? 195 ASP A CB 1 ATOM 1322 C CG . ASP A 1 168 ? -79.900 -9.118 -2.291 1.00 24.33 ? 195 ASP A CG 1 ATOM 1323 O OD1 . ASP A 1 168 ? -80.266 -10.246 -2.674 1.00 23.42 ? 195 ASP A OD1 1 ATOM 1324 O OD2 . ASP A 1 168 ? -80.661 -8.130 -2.286 1.00 25.59 1 195 ASP A OD2 1 ATOM 1325 N N . LEU A 1 169 ? -75.326 -10.711 -2.137 1.00 25.13 ? 196 LEU A N 1 ATOM 1326 C CA . LEU A 1 169 ? -73.999 -10.806 -1.529 1.00 22.39 ? 196 LEU A CA 1 ATOM 1327 C C . LEU A 1 169 ? -72.909 -10.448 -2.527 1.00 20.59 ? 196 LEU A C 1 ATOM 1328 O O . LEU A 1 169 ? -71.929 -11.171 -2.661 1.00 18.59 ? 196 LEU A O 1 ATOM 1329 C CB . LEU A 1 169 ? -73.762 -12.222 -1.003 1.00 13.10 ? 196 LEU A CB 1 ATOM 1330 C CG . LEU A 1 169 ? -74.877 -12.761 -0.107 1.00 14.17 ? 196 LEU A CG 1 ATOM 1331 C CD1 . LEU A 1 169 ? -74.455 -14.057 0.545 1.00 12.93 ? 196 LEU A CD1 1 ATOM 1332 C CD2 . LEU A 1 169 ? -75.278 -11.743 0.946 1.00 14.41 ? 196 LEU A CD2 1 ATOM 1333 N N . GLU A 1 170 ? -73.088 -9.326 -3.218 1.00 25.99 ? 197 GLU A N 1 ATOM 1334 C CA . GLU A 1 170 ? -72.226 -8.939 -4.334 1.00 24.76 ? 197 GLU A CA 1 ATOM 1335 C C . GLU A 1 170 ? -70.808 -8.615 -3.889 1.00 24.20 ? 197 GLU A C 1 ATOM 1336 O O . GLU A 1 170 ? -69.861 -8.689 -4.677 1.00 22.53 ? 197 GLU A O 1 ATOM 1337 C CB . GLU A 1 170 ? -72.822 -7.728 -5.061 1.00 29.83 ? 197 GLU A CB 1 ATOM 1338 C CG . GLU A 1 170 ? -72.801 -6.435 -4.244 1.00 28.71 ? 197 GLU A CG 1 ATOM 1339 C CD . GLU A 1 170 ? -73.784 -5.394 -4.752 1.00 35.26 ? 197 GLU A CD 1 ATOM 1340 O OE1 . GLU A 1 170 ? -74.551 -5.706 -5.691 1.00 44.66 ? 197 GLU A OE1 1 ATOM 1341 O OE2 . GLU A 1 170 ? -73.798 -4.269 -4.204 1.00 28.09 1 197 GLU A OE2 1 ATOM 1342 N N . ASN A 1 171 ? -70.665 -8.252 -2.621 1.00 24.43 ? 198 ASN A N 1 ATOM 1343 C CA . ASN A 1 171 ? -69.375 -7.827 -2.105 1.00 23.12 ? 198 ASN A CA 1 ATOM 1344 C C . ASN A 1 171 ? -68.731 -8.876 -1.225 1.00 18.54 ? 198 ASN A C 1 ATOM 1345 O O . ASN A 1 171 ? -67.695 -8.627 -0.612 1.00 16.98 ? 198 ASN A O 1 ATOM 1346 C CB . ASN A 1 171 ? -69.510 -6.503 -1.359 1.00 21.41 ? 198 ASN A CB 1 ATOM 1347 C CG . ASN A 1 171 ? -69.714 -5.333 -2.300 1.00 33.03 ? 198 ASN A CG 1 ATOM 1348 O OD1 . ASN A 1 171 ? -69.687 -5.495 -3.526 1.00 30.11 ? 198 ASN A OD1 1 ATOM 1349 N ND2 . ASN A 1 171 ? -69.927 -4.147 -1.736 1.00 34.98 ? 198 ASN A ND2 1 ATOM 1350 N N . LEU A 1 172 ? -69.346 -10.053 -1.175 1.00 17.59 ? 199 LEU A N 1 ATOM 1351 C CA . LEU A 1 172 ? -68.819 -11.143 -0.372 1.00 13.41 ? 199 LEU A CA 1 ATOM 1352 C C . LEU A 1 172 ? -67.536 -11.659 -0.987 1.00 16.18 ? 199 LEU A C 1 ATOM 1353 O O . LEU A 1 172 ? -67.526 -12.104 -2.138 1.00 15.95 ? 199 LEU A O 1 ATOM 1354 C CB . LEU A 1 172 ? -69.819 -12.281 -0.268 1.00 10.86 ? 199 LEU A CB 1 ATOM 1355 C CG . LEU A 1 172 ? -69.622 -13.113 0.991 1.00 8.76 ? 199 LEU A CG 1 ATOM 1356 C CD1 . LEU A 1 172 ? -70.124 -12.329 2.177 1.00 9.03 ? 199 LEU A CD1 1 ATOM 1357 C CD2 . LEU A 1 172 ? -70.337 -14.442 0.887 1.00 10.58 ? 199 LEU A CD2 1 ATOM 1358 N N . GLU A 1 173 ? -66.458 -11.592 -0.208 1.00 15.70 ? 200 GLU A N 1 ATOM 1359 C CA . GLU A 1 173 ? -65.144 -12.021 -0.660 1.00 11.54 ? 200 GLU A CA 1 ATOM 1360 C C . GLU A 1 173 ? -64.752 -13.381 -0.089 1.00 13.97 ? 200 GLU A C 1 ATOM 1361 O O . GLU A 1 173 ? -64.019 -14.131 -0.730 1.00 14.66 ? 200 GLU A O 1 ATOM 1362 C CB . GLU A 1 173 ? -64.094 -10.984 -0.283 1.00 12.14 ? 200 GLU A CB 1 ATOM 1363 C CG . GLU A 1 173 ? -64.357 -9.607 -0.845 1.00 16.97 ? 200 GLU A CG 1 ATOM 1364 C CD . GLU A 1 173 ? -63.209 -8.650 -0.589 1.00 20.57 ? 200 GLU A CD 1 ATOM 1365 O OE1 . GLU A 1 173 ? -62.065 -8.974 -0.974 1.00 17.13 ? 200 GLU A OE1 1 ATOM 1366 O OE2 . GLU A 1 173 ? -63.451 -7.576 0.001 1.00 21.85 1 200 GLU A OE2 1 ATOM 1367 N N . SER A 1 174 ? -65.236 -13.700 1.111 1.00 12.39 ? 201 SER A N 1 ATOM 1368 C CA . SER A 1 174 ? -64.866 -14.954 1.771 1.00 9.51 ? 201 SER A CA 1 ATOM 1369 C C . SER A 1 174 ? -66.039 -15.693 2.415 1.00 9.78 ? 201 SER A C 1 ATOM 1370 O O . SER A 1 174 ? -66.870 -15.093 3.094 1.00 10.24 ? 201 SER A O 1 ATOM 1371 C CB . SER A 1 174 ? -63.790 -14.696 2.816 1.00 9.82 ? 201 SER A CB 1 ATOM 1372 O OG . SER A 1 174 ? -64.213 -13.687 3.714 1.00 13.20 ? 201 SER A OG 1 ATOM 1373 N N . ILE A 1 175 ? -66.075 -17.007 2.208 1.00 9.78 ? 202 ILE A N 1 ATOM 1374 C CA . ILE A 1 175 ? -67.153 -17.868 2.688 1.00 9.37 ? 202 ILE A CA 1 ATOM 1375 C C . ILE A 1 175 ? -66.606 -18.934 3.631 1.00 10.98 ? 202 ILE A C 1 ATOM 1376 O O . ILE A 1 175 ? -65.643 -19.624 3.295 1.00 11.63 ? 202 ILE A O 1 ATOM 1377 C CB . ILE A 1 175 ? -67.828 -18.606 1.510 1.00 10.31 ? 202 ILE A CB 1 ATOM 1378 C CG1 . ILE A 1 175 ? -68.782 -17.689 0.749 1.00 13.32 ? 202 ILE A CG1 1 ATOM 1379 C CG2 . ILE A 1 175 ? -68.592 -19.809 1.997 1.00 8.71 ? 202 ILE A CG2 1 ATOM 1380 C CD1 . ILE A 1 175 ? -69.370 -18.331 -0.501 1.00 9.05 ? 202 ILE A CD1 1 ATOM 1381 N N . GLU A 1 176 ? -67.223 -19.080 4.801 1.00 9.19 ? 203 GLU A N 1 ATOM 1382 C CA . GLU A 1 176 ? -66.833 -20.129 5.738 1.00 9.75 ? 203 GLU A CA 1 ATOM 1383 C C . GLU A 1 176 ? -68.016 -20.991 6.156 1.00 10.58 ? 203 GLU A C 1 ATOM 1384 O O . GLU A 1 176 ? -68.810 -20.591 7.011 1.00 10.32 ? 203 GLU A O 1 ATOM 1385 C CB . GLU A 1 176 ? -66.164 -19.533 6.979 1.00 10.53 ? 203 GLU A CB 1 ATOM 1386 C CG . GLU A 1 176 ? -65.824 -20.555 8.063 1.00 10.68 ? 203 GLU A CG 1 ATOM 1387 C CD . GLU A 1 176 ? -64.998 -21.717 7.540 1.00 14.96 ? 203 GLU A CD 1 ATOM 1388 O OE1 . GLU A 1 176 ? -63.792 -21.798 7.875 1.00 17.16 ? 203 GLU A OE1 1 ATOM 1389 O OE2 . GLU A 1 176 ? -65.553 -22.552 6.790 1.00 14.12 1 203 GLU A OE2 1 ATOM 1390 N N . PHE A 1 177 ? -68.119 -22.179 5.561 1.00 10.92 ? 204 PHE A N 1 ATOM 1391 C CA . PHE A 1 177 ? -69.206 -23.109 5.871 1.00 10.72 ? 204 PHE A CA 1 ATOM 1392 C C . PHE A 1 177 ? -68.711 -24.470 6.360 1.00 10.16 ? 204 PHE A C 1 ATOM 1393 O O . PHE A 1 177 ? -69.310 -25.498 6.050 1.00 11.52 ? 204 PHE A O 1 ATOM 1394 C CB . PHE A 1 177 ? -70.106 -23.312 4.651 1.00 8.68 ? 204 PHE A CB 1 ATOM 1395 C CG . PHE A 1 177 ? -70.890 -22.102 4.269 1.00 5.96 ? 204 PHE A CG 1 ATOM 1396 C CD1 . PHE A 1 177 ? -71.399 -21.257 5.238 1.00 7.24 ? 204 PHE A CD1 1 ATOM 1397 C CD2 . PHE A 1 177 ? -71.123 -21.809 2.943 1.00 5.31 ? 204 PHE A CD2 1 ATOM 1398 C CE1 . PHE A 1 177 ? -72.131 -20.133 4.886 1.00 6.89 ? 204 PHE A CE1 1 ATOM 1399 C CE2 . PHE A 1 177 ? -71.848 -20.687 2.583 1.00 7.68 ? 204 PHE A CE2 1 ATOM 1400 C CZ . PHE A 1 177 ? -72.352 -19.848 3.556 1.00 6.53 ? 204 PHE A CZ 1 ATOM 1401 N N . GLY A 1 178 ? -67.627 -24.477 7.124 1.00 8.98 ? 205 GLY A N 1 ATOM 1402 C CA . GLY A 1 178 ? -67.109 -25.713 7.678 1.00 9.08 ? 205 GLY A CA 1 ATOM 1403 C C . GLY A 1 178 ? -67.996 -26.300 8.759 1.00 9.24 ? 205 GLY A C 1 ATOM 1404 O O . GLY A 1 178 ? -68.720 -25.573 9.438 1.00 10.63 ? 205 GLY A O 1 ATOM 1405 N N . SER A 1 179 ? -67.928 -27.618 8.925 1.00 8.37 ? 206 SER A N 1 ATOM 1406 C CA . SER A 1 179 ? -68.726 -28.338 9.923 1.00 14.02 ? 206 SER A CA 1 ATOM 1407 C C . SER A 1 179 ? -70.242 -28.175 9.728 1.00 18.57 ? 206 SER A C 1 ATOM 1408 O O . SER A 1 179 ? -71.021 -28.129 10.688 1.00 19.96 ? 206 SER A O 1 ATOM 1409 C CB . SER A 1 179 ? -68.297 -27.983 11.349 1.00 16.46 ? 206 SER A CB 1 ATOM 1410 O OG . SER A 1 179 ? -68.390 -26.589 11.578 1.00 17.98 ? 206 SER A OG 1 ATOM 1411 N N . ASN A 1 180 ? -70.641 -28.078 8.466 1.00 16.31 ? 207 ASN A N 1 ATOM 1412 C CA . ASN A 1 180 ? -72.031 -28.199 8.067 1.00 12.29 ? 207 ASN A CA 1 ATOM 1413 C C . ASN A 1 180 ? -72.175 -29.550 7.381 1.00 14.86 ? 207 ASN A C 1 ATOM 1414 O O . ASN A 1 180 ? -71.230 -30.335 7.370 1.00 18.36 ? 207 ASN A O 1 ATOM 1415 C CB . ASN A 1 180 ? -72.405 -27.063 7.124 1.00 11.93 ? 207 ASN A CB 1 ATOM 1416 C CG . ASN A 1 180 ? -72.430 -25.722 7.821 1.00 10.96 ? 207 ASN A CG 1 ATOM 1417 O OD1 . ASN A 1 180 ? -73.088 -25.562 8.851 1.00 12.64 ? 207 ASN A OD1 1 ATOM 1418 N ND2 . ASN A 1 180 ? -71.706 -24.751 7.272 1.00 7.23 ? 207 ASN A ND2 1 ATOM 1419 N N . LYS A 1 181 ? -73.334 -29.835 6.801 1.00 14.21 ? 208 LYS A N 1 ATOM 1420 C CA . LYS A 1 181 ? -73.536 -31.148 6.198 1.00 14.92 ? 208 LYS A CA 1 ATOM 1421 C C . LYS A 1 181 ? -73.626 -31.113 4.677 1.00 12.91 ? 208 LYS A C 1 ATOM 1422 O O . LYS A 1 181 ? -74.211 -32.015 4.084 1.00 15.52 ? 208 LYS A O 1 ATOM 1423 C CB . LYS A 1 181 ? -74.787 -31.824 6.765 1.00 16.36 ? 208 LYS A CB 1 ATOM 1424 C CG . LYS A 1 181 ? -74.670 -32.318 8.197 1.00 16.28 ? 208 LYS A CG 1 ATOM 1425 C CD . LYS A 1 181 ? -75.847 -33.214 8.529 1.00 17.60 ? 208 LYS A CD 1 ATOM 1426 C CE . LYS A 1 181 ? -75.832 -33.660 9.972 1.00 20.44 ? 208 LYS A CE 1 ATOM 1427 N NZ . LYS A 1 181 ? -77.005 -34.528 10.280 1.00 25.11 1 208 LYS A NZ 1 ATOM 1428 N N . LEU A 1 182 ? -73.046 -30.090 4.052 1.00 10.16 ? 209 LEU A N 1 ATOM 1429 C CA . LEU A 1 182 ? -73.131 -29.930 2.597 1.00 11.14 ? 209 LEU A CA 1 ATOM 1430 C C . LEU A 1 182 ? -72.725 -31.180 1.826 1.00 11.81 ? 209 LEU A C 1 ATOM 1431 O O . LEU A 1 182 ? -71.576 -31.607 1.875 1.00 11.03 ? 209 LEU A O 1 ATOM 1432 C CB . LEU A 1 182 ? -72.282 -28.756 2.117 1.00 9.74 ? 209 LEU A CB 1 ATOM 1433 C CG . LEU A 1 182 ? -72.570 -27.373 2.688 1.00 8.37 ? 209 LEU A CG 1 ATOM 1434 C CD1 . LEU A 1 182 ? -72.044 -26.324 1.734 1.00 6.17 ? 209 LEU A CD1 1 ATOM 1435 C CD2 . LEU A 1 182 ? -74.048 -27.181 2.956 1.00 11.15 ? 209 LEU A CD2 1 ATOM 1436 N N . ARG A 1 183 ? -73.676 -31.754 1.100 1.00 15.93 ? 210 ARG A N 1 ATOM 1437 C CA . ARG A 1 183 ? -73.425 -32.982 0.360 1.00 17.51 ? 210 ARG A CA 1 ATOM 1438 C C . ARG A 1 183 ? -73.114 -32.663 -1.094 1.00 15.54 ? 210 ARG A C 1 ATOM 1439 O O . ARG A 1 183 ? -72.593 -33.501 -1.828 1.00 14.08 ? 210 ARG A O 1 ATOM 1440 C CB . ARG A 1 183 ? -74.632 -33.918 0.454 1.00 21.08 ? 210 ARG A CB 1 ATOM 1441 C CG . ARG A 1 183 ? -75.437 -33.757 1.740 1.00 21.68 ? 210 ARG A CG 1 ATOM 1442 C CD . ARG A 1 183 ? -76.449 -34.875 1.934 1.00 22.64 ? 210 ARG A CD 1 ATOM 1443 N NE . ARG A 1 183 ? -77.238 -34.682 3.147 1.00 28.20 ? 210 ARG A NE 1 ATOM 1444 C CZ . ARG A 1 183 ? -76.857 -35.071 4.362 1.00 36.38 ? 210 ARG A CZ 1 ATOM 1445 N NH1 . ARG A 1 183 ? -75.691 -35.678 4.535 1.00 36.88 1 210 ARG A NH1 1 ATOM 1446 N NH2 . ARG A 1 183 ? -77.642 -34.851 5.409 1.00 36.08 ? 210 ARG A NH2 1 ATOM 1447 N N . GLN A 1 184 ? -73.432 -31.440 -1.502 1.00 15.65 ? 211 GLN A N 1 ATOM 1448 C CA . GLN A 1 184 ? -73.186 -31.019 -2.873 1.00 18.99 ? 211 GLN A CA 1 ATOM 1449 C C . GLN A 1 184 ? -72.907 -29.530 -2.972 1.00 17.33 ? 211 GLN A C 1 ATOM 1450 O O . GLN A 1 184 ? -73.478 -28.727 -2.241 1.00 16.65 ? 211 GLN A O 1 ATOM 1451 C CB . GLN A 1 184 ? -74.383 -31.358 -3.752 1.00 20.70 ? 211 GLN A CB 1 ATOM 1452 C CG . GLN A 1 184 ? -74.107 -31.248 -5.230 1.00 20.03 ? 211 GLN A CG 1 ATOM 1453 C CD . GLN A 1 184 ? -74.308 -32.569 -5.927 1.00 31.61 ? 211 GLN A CD 1 ATOM 1454 O OE1 . GLN A 1 184 ? -74.818 -33.519 -5.332 1.00 25.77 ? 211 GLN A OE1 1 ATOM 1455 N NE2 . GLN A 1 184 ? -73.904 -32.643 -7.192 1.00 52.47 ? 211 GLN A NE2 1 ATOM 1456 N N . MET A 1 185 ? -72.026 -29.168 -3.892 1.00 19.80 ? 212 MET A N 1 ATOM 1457 C CA . MET A 1 185 ? -71.747 -27.771 -4.169 1.00 21.76 ? 212 MET A CA 1 ATOM 1458 C C . MET A 1 185 ? -72.931 -27.100 -4.886 1.00 25.52 ? 212 MET A C 1 ATOM 1459 O O . MET A 1 185 ? -73.386 -27.575 -5.936 1.00 25.46 ? 212 MET A O 1 ATOM 1460 C CB . MET A 1 185 ? -70.476 -27.660 -5.012 1.00 20.41 ? 212 MET A CB 1 ATOM 1461 C CG . MET A 1 185 ? -70.170 -26.257 -5.489 1.00 22.00 ? 212 MET A CG 1 ATOM 1462 S SD . MET A 1 185 ? -69.390 -25.265 -4.213 1.00 12.68 ? 212 MET A SD 1 ATOM 1463 C CE . MET A 1 185 ? -67.884 -26.207 -4.014 1.00 19.65 ? 212 MET A CE 1 ATOM 1464 N N . PRO A 1 186 ? -73.442 -25.999 -4.308 1.00 20.62 ? 213 PRO A N 1 ATOM 1465 C CA . PRO A 1 186 ? -74.508 -25.194 -4.914 1.00 20.01 ? 213 PRO A CA 1 ATOM 1466 C C . PRO A 1 186 ? -74.126 -24.717 -6.301 1.00 22.67 ? 213 PRO A C 1 ATOM 1467 O O . PRO A 1 186 ? -73.060 -24.128 -6.470 1.00 20.06 ? 213 PRO A O 1 ATOM 1468 C CB . PRO A 1 186 ? -74.609 -23.994 -3.973 1.00 15.24 ? 213 PRO A CB 1 ATOM 1469 C CG . PRO A 1 186 ? -74.200 -24.533 -2.663 1.00 16.68 ? 213 PRO A CG 1 ATOM 1470 C CD . PRO A 1 186 ? -73.114 -25.534 -2.950 1.00 15.47 ? 213 PRO A CD 1 ATOM 1471 N N . ARG A 1 187 ? -74.988 -24.969 -7.280 1.00 31.92 ? 214 ARG A N 1 ATOM 1472 C CA . ARG A 1 187 ? -74.740 -24.526 -8.647 1.00 32.55 ? 214 ARG A CA 1 ATOM 1473 C C . ARG A 1 187 ? -75.110 -23.061 -8.827 1.00 22.28 ? 214 ARG A C 1 ATOM 1474 O O . ARG A 1 187 ? -75.940 -22.528 -8.093 1.00 17.22 ? 214 ARG A O 1 ATOM 1475 C CB . ARG A 1 187 ? -75.509 -25.395 -9.643 1.00 36.71 ? 214 ARG A CB 1 ATOM 1476 C CG . ARG A 1 187 ? -75.085 -26.858 -9.634 1.00 50.99 ? 214 ARG A CG 1 ATOM 1477 C CD . ARG A 1 187 ? -73.624 -27.023 -10.036 1.00 50.52 ? 214 ARG A CD 1 ATOM 1478 N NE . ARG A 1 187 ? -73.234 -28.429 -10.120 1.00 51.61 ? 214 ARG A NE 1 ATOM 1479 C CZ . ARG A 1 187 ? -73.500 -29.219 -11.158 1.00 54.06 ? 214 ARG A CZ 1 ATOM 1480 N NH1 . ARG A 1 187 ? -74.168 -28.746 -12.203 1.00 45.23 1 214 ARG A NH1 1 ATOM 1481 N NH2 . ARG A 1 187 ? -73.104 -30.485 -11.148 1.00 55.58 ? 214 ARG A NH2 1 ATOM 1482 N N . GLY A 1 188 ? -74.474 -22.419 -9.801 1.00 25.67 ? 215 GLY A N 1 ATOM 1483 C CA . GLY A 1 188 ? -74.747 -21.031 -10.135 1.00 30.31 ? 215 GLY A CA 1 ATOM 1484 C C . GLY A 1 188 ? -74.646 -20.066 -8.970 1.00 28.95 ? 215 GLY A C 1 ATOM 1485 O O . GLY A 1 188 ? -75.627 -19.414 -8.610 1.00 31.08 ? 215 GLY A O 1 ATOM 1486 N N . ILE A 1 189 ? -73.459 -19.965 -8.379 1.00 29.26 ? 216 ILE A N 1 ATOM 1487 C CA . ILE A 1 189 ? -73.273 -19.100 -7.219 1.00 27.07 ? 216 ILE A CA 1 ATOM 1488 C C . ILE A 1 189 ? -72.163 -18.072 -7.411 1.00 27.63 ? 216 ILE A C 1 ATOM 1489 O O . ILE A 1 189 ? -72.236 -16.972 -6.862 1.00 26.17 ? 216 ILE A O 1 ATOM 1490 C CB . ILE A 1 189 ? -72.980 -19.913 -5.942 1.00 22.68 ? 216 ILE A CB 1 ATOM 1491 C CG1 . ILE A 1 189 ? -71.817 -20.874 -6.188 1.00 21.46 ? 216 ILE A CG1 1 ATOM 1492 C CG2 . ILE A 1 189 ? -74.216 -20.679 -5.504 1.00 23.05 ? 216 ILE A CG2 1 ATOM 1493 C CD1 . ILE A 1 189 ? -71.398 -21.643 -4.972 1.00 19.85 ? 216 ILE A CD1 1 ATOM 1494 N N . PHE A 1 190 ? -71.141 -18.422 -8.189 1.00 24.94 ? 217 PHE A N 1 ATOM 1495 C CA . PHE A 1 190 ? -69.972 -17.555 -8.312 1.00 21.05 ? 217 PHE A CA 1 ATOM 1496 C C . PHE A 1 190 ? -70.268 -16.330 -9.159 1.00 20.96 ? 217 PHE A C 1 ATOM 1497 O O . PHE A 1 190 ? -69.558 -15.328 -9.084 1.00 20.62 ? 217 PHE A O 1 ATOM 1498 C CB . PHE A 1 190 ? -68.761 -18.328 -8.834 1.00 18.17 ? 217 PHE A CB 1 ATOM 1499 C CG . PHE A 1 190 ? -68.408 -19.520 -7.991 1.00 20.84 ? 217 PHE A CG 1 ATOM 1500 C CD1 . PHE A 1 190 ? -68.131 -19.370 -6.646 1.00 15.15 ? 217 PHE A CD1 1 ATOM 1501 C CD2 . PHE A 1 190 ? -68.373 -20.793 -8.537 1.00 27.01 ? 217 PHE A CD2 1 ATOM 1502 C CE1 . PHE A 1 190 ? -67.825 -20.462 -5.864 1.00 14.12 ? 217 PHE A CE1 1 ATOM 1503 C CE2 . PHE A 1 190 ? -68.057 -21.892 -7.755 1.00 20.89 ? 217 PHE A CE2 1 ATOM 1504 C CZ . PHE A 1 190 ? -67.789 -21.724 -6.418 1.00 14.36 ? 217 PHE A CZ 1 ATOM 1505 N N . GLY A 1 191 ? -71.336 -16.413 -9.946 1.00 20.36 ? 218 GLY A N 1 ATOM 1506 C CA . GLY A 1 191 ? -71.793 -15.287 -10.735 1.00 17.99 ? 218 GLY A CA 1 ATOM 1507 C C . GLY A 1 191 ? -72.358 -14.170 -9.877 1.00 18.79 ? 218 GLY A C 1 ATOM 1508 O O . GLY A 1 191 ? -72.332 -13.002 -10.268 1.00 25.30 ? 218 GLY A O 1 ATOM 1509 N N . LYS A 1 192 ? -72.868 -14.518 -8.702 1.00 14.92 ? 219 LYS A N 1 ATOM 1510 C CA . LYS A 1 192 ? -73.474 -13.520 -7.833 1.00 16.18 ? 219 LYS A CA 1 ATOM 1511 C C . LYS A 1 192 ? -72.444 -12.905 -6.893 1.00 17.72 ? 219 LYS A C 1 ATOM 1512 O O . LYS A 1 192 ? -72.691 -11.871 -6.269 1.00 15.58 ? 219 LYS A O 1 ATOM 1513 C CB . LYS A 1 192 ? -74.636 -14.125 -7.041 1.00 18.28 ? 219 LYS A CB 1 ATOM 1514 C CG . LYS A 1 192 ? -75.697 -14.814 -7.904 1.00 31.77 ? 219 LYS A CG 1 ATOM 1515 C CD . LYS A 1 192 ? -77.126 -14.522 -7.421 1.00 30.43 ? 219 LYS A CD 1 ATOM 1516 C CE . LYS A 1 192 ? -77.533 -13.065 -7.675 1.00 26.81 ? 219 LYS A CE 1 ATOM 1517 N NZ . LYS A 1 192 ? -77.720 -12.740 -9.126 1.00 22.51 1 219 LYS A NZ 1 ATOM 1518 N N . MET A 1 193 ? -71.285 -13.551 -6.803 1.00 19.49 ? 220 MET A N 1 ATOM 1519 C CA . MET A 1 193 ? -70.203 -13.091 -5.940 1.00 21.02 ? 220 MET A CA 1 ATOM 1520 C C . MET A 1 193 ? -68.903 -13.033 -6.729 1.00 19.61 ? 220 MET A C 1 ATOM 1521 O O . MET A 1 193 ? -68.113 -13.976 -6.700 1.00 18.60 ? 220 MET A O 1 ATOM 1522 C CB . MET A 1 193 ? -70.047 -14.026 -4.740 1.00 16.69 ? 220 MET A CB 1 ATOM 1523 C CG . MET A 1 193 ? -71.299 -14.148 -3.886 1.00 14.22 ? 220 MET A CG 1 ATOM 1524 S SD . MET A 1 193 ? -71.192 -15.463 -2.661 1.00 13.25 ? 220 MET A SD 1 ATOM 1525 C CE . MET A 1 193 ? -70.753 -16.850 -3.708 1.00 13.05 ? 220 MET A CE 1 ATOM 1526 N N . PRO A 1 194 ? -68.677 -11.914 -7.433 1.00 19.45 ? 221 PRO A N 1 ATOM 1527 C CA . PRO A 1 194 ? -67.548 -11.752 -8.353 1.00 22.74 ? 221 PRO A CA 1 ATOM 1528 C C . PRO A 1 194 ? -66.249 -11.361 -7.647 1.00 21.96 ? 221 PRO A C 1 ATOM 1529 O O . PRO A 1 194 ? -65.217 -11.219 -8.303 1.00 16.62 ? 221 PRO A O 1 ATOM 1530 C CB . PRO A 1 194 ? -68.009 -10.610 -9.272 1.00 22.53 ? 221 PRO A CB 1 ATOM 1531 C CG . PRO A 1 194 ? -69.305 -10.074 -8.671 1.00 19.84 ? 221 PRO A CG 1 ATOM 1532 C CD . PRO A 1 194 ? -69.453 -10.673 -7.314 1.00 18.38 ? 221 PRO A CD 1 ATOM 1533 N N . LYS A 1 195 ? -66.308 -11.191 -6.329 1.00 19.47 ? 222 LYS A N 1 ATOM 1534 C CA . LYS A 1 195 ? -65.141 -10.788 -5.555 1.00 16.58 ? 222 LYS A CA 1 ATOM 1535 C C . LYS A 1 195 ? -64.771 -11.848 -4.528 1.00 16.75 ? 222 LYS A C 1 ATOM 1536 O O . LYS A 1 195 ? -63.968 -11.601 -3.628 1.00 14.50 ? 222 LYS A O 1 ATOM 1537 C CB . LYS A 1 195 ? -65.407 -9.460 -4.848 1.00 18.22 ? 222 LYS A CB 1 ATOM 1538 C CG . LYS A 1 195 ? -65.376 -8.252 -5.762 1.00 22.90 ? 222 LYS A CG 1 ATOM 1539 C CD . LYS A 1 195 ? -65.829 -6.999 -5.032 1.00 25.94 ? 222 LYS A CD 1 ATOM 1540 C CE . LYS A 1 195 ? -65.055 -6.798 -3.741 1.00 22.49 ? 222 LYS A CE 1 ATOM 1541 N NZ . LYS A 1 195 ? -65.505 -5.570 -3.031 1.00 30.11 1 222 LYS A NZ 1 ATOM 1542 N N . LEU A 1 196 ? -65.368 -13.026 -4.662 1.00 17.05 ? 223 LEU A N 1 ATOM 1543 C CA . LEU A 1 196 ? -65.154 -14.093 -3.697 1.00 14.71 ? 223 LEU A CA 1 ATOM 1544 C C . LEU A 1 196 ? -63.734 -14.627 -3.811 1.00 12.87 ? 223 LEU A C 1 ATOM 1545 O O . LEU A 1 196 ? -63.305 -15.010 -4.895 1.00 14.53 ? 223 LEU A O 1 ATOM 1546 C CB . LEU A 1 196 ? -66.156 -15.223 -3.928 1.00 12.75 ? 223 LEU A CB 1 ATOM 1547 C CG . LEU A 1 196 ? -66.089 -16.368 -2.919 1.00 10.15 ? 223 LEU A CG 1 ATOM 1548 C CD1 . LEU A 1 196 ? -66.582 -15.915 -1.558 1.00 9.03 ? 223 LEU A CD1 1 ATOM 1549 C CD2 . LEU A 1 196 ? -66.879 -17.560 -3.415 1.00 9.57 ? 223 LEU A CD2 1 ATOM 1550 N N . LYS A 1 197 ? -63.004 -14.654 -2.699 1.00 10.43 ? 224 LYS A N 1 ATOM 1551 C CA . LYS A 1 197 ? -61.621 -15.126 -2.722 1.00 10.77 ? 224 LYS A CA 1 ATOM 1552 C C . LYS A 1 197 ? -61.397 -16.389 -1.903 1.00 12.29 ? 224 LYS A C 1 ATOM 1553 O O . LYS A 1 197 ? -60.756 -17.324 -2.374 1.00 15.06 ? 224 LYS A O 1 ATOM 1554 C CB . LYS A 1 197 ? -60.649 -14.022 -2.296 1.00 10.79 ? 224 LYS A CB 1 ATOM 1555 C CG . LYS A 1 197 ? -60.349 -13.026 -3.403 1.00 9.04 ? 224 LYS A CG 1 ATOM 1556 C CD . LYS A 1 197 ? -60.107 -11.639 -2.856 1.00 10.64 ? 224 LYS A CD 1 ATOM 1557 C CE . LYS A 1 197 ? -60.742 -10.590 -3.756 1.00 16.32 ? 224 LYS A CE 1 ATOM 1558 N NZ . LYS A 1 197 ? -60.837 -9.264 -3.077 1.00 23.50 1 224 LYS A NZ 1 ATOM 1559 N N . GLN A 1 198 ? -61.919 -16.427 -0.683 1.00 10.82 ? 225 GLN A N 1 ATOM 1560 C CA . GLN A 1 198 ? -61.762 -17.618 0.145 1.00 11.29 ? 225 GLN A CA 1 ATOM 1561 C C . GLN A 1 198 ? -63.033 -18.461 0.151 1.00 12.00 ? 225 GLN A C 1 ATOM 1562 O O . GLN A 1 198 ? -64.132 -17.941 0.311 1.00 15.91 ? 225 GLN A O 1 ATOM 1563 C CB . GLN A 1 198 ? -61.364 -17.243 1.575 1.00 11.16 ? 225 GLN A CB 1 ATOM 1564 C CG . GLN A 1 198 ? -60.881 -18.420 2.416 1.00 11.86 ? 225 GLN A CG 1 ATOM 1565 C CD . GLN A 1 198 ? -59.585 -19.030 1.896 1.00 14.81 ? 225 GLN A CD 1 ATOM 1566 O OE1 . GLN A 1 198 ? -58.595 -18.324 1.677 1.00 14.71 ? 225 GLN A OE1 1 ATOM 1567 N NE2 . GLN A 1 198 ? -59.588 -20.349 1.693 1.00 11.15 ? 225 GLN A NE2 1 ATOM 1568 N N . LEU A 1 199 ? -62.884 -19.767 -0.023 1.00 10.21 ? 226 LEU A N 1 ATOM 1569 C CA . LEU A 1 199 ? -64.034 -20.660 -0.006 1.00 10.36 ? 226 LEU A CA 1 ATOM 1570 C C . LEU A 1 199 ? -63.793 -21.853 0.923 1.00 13.32 ? 226 LEU A C 1 ATOM 1571 O O . LEU A 1 199 ? -63.395 -22.928 0.473 1.00 15.90 ? 226 LEU A O 1 ATOM 1572 C CB . LEU A 1 199 ? -64.336 -21.137 -1.430 1.00 11.57 ? 226 LEU A CB 1 ATOM 1573 C CG . LEU A 1 199 ? -65.518 -22.080 -1.671 1.00 8.94 ? 226 LEU A CG 1 ATOM 1574 C CD1 . LEU A 1 199 ? -66.827 -21.396 -1.350 1.00 8.77 ? 226 LEU A CD1 1 ATOM 1575 C CD2 . LEU A 1 199 ? -65.508 -22.575 -3.097 1.00 8.04 ? 226 LEU A CD2 1 ATOM 1576 N N . ASN A 1 200 ? -64.021 -21.671 2.221 1.00 11.89 ? 227 ASN A N 1 ATOM 1577 C CA . ASN A 1 200 ? -63.788 -22.759 3.172 1.00 12.69 ? 227 ASN A CA 1 ATOM 1578 C C . ASN A 1 200 ? -64.968 -23.715 3.246 1.00 12.89 ? 227 ASN A C 1 ATOM 1579 O O . ASN A 1 200 ? -66.051 -23.344 3.704 1.00 12.30 ? 227 ASN A O 1 ATOM 1580 C CB . ASN A 1 200 ? -63.460 -22.233 4.574 1.00 12.51 ? 227 ASN A CB 1 ATOM 1581 C CG . ASN A 1 200 ? -62.158 -21.466 4.622 1.00 11.92 ? 227 ASN A CG 1 ATOM 1582 O OD1 . ASN A 1 200 ? -61.393 -21.460 3.656 1.00 13.27 ? 227 ASN A OD1 1 ATOM 1583 N ND2 . ASN A 1 200 ? -61.895 -20.817 5.751 1.00 9.49 ? 227 ASN A ND2 1 ATOM 1584 N N . LEU A 1 201 ? -64.748 -24.949 2.801 1.00 11.68 ? 228 LEU A N 1 ATOM 1585 C CA . LEU A 1 201 ? -65.795 -25.964 2.821 1.00 12.02 ? 228 LEU A CA 1 ATOM 1586 C C . LEU A 1 201 ? -65.342 -27.247 3.502 1.00 12.60 ? 228 LEU A C 1 ATOM 1587 O O . LEU A 1 201 ? -65.812 -28.335 3.167 1.00 14.53 ? 228 LEU A O 1 ATOM 1588 C CB . LEU A 1 201 ? -66.268 -26.263 1.405 1.00 10.76 ? 228 LEU A CB 1 ATOM 1589 C CG . LEU A 1 201 ? -67.044 -25.100 0.807 1.00 10.45 ? 228 LEU A CG 1 ATOM 1590 C CD1 . LEU A 1 201 ? -67.085 -25.228 -0.692 1.00 11.00 ? 228 LEU A CD1 1 ATOM 1591 C CD2 . LEU A 1 201 ? -68.439 -25.090 1.391 1.00 10.07 ? 228 LEU A CD2 1 ATOM 1592 N N . TRP A 1 202 ? -64.435 -27.109 4.463 1.00 10.57 ? 229 TRP A N 1 ATOM 1593 C CA . TRP A 1 202 ? -63.936 -28.247 5.221 1.00 9.81 ? 229 TRP A CA 1 ATOM 1594 C C . TRP A 1 202 ? -65.016 -28.872 6.105 1.00 9.68 ? 229 TRP A C 1 ATOM 1595 O O . TRP A 1 202 ? -66.036 -28.247 6.383 1.00 9.25 ? 229 TRP A O 1 ATOM 1596 C CB . TRP A 1 202 ? -62.731 -27.826 6.062 1.00 8.26 ? 229 TRP A CB 1 ATOM 1597 C CG . TRP A 1 202 ? -62.972 -26.612 6.902 1.00 7.73 ? 229 TRP A CG 1 ATOM 1598 C CD1 . TRP A 1 202 ? -62.905 -25.311 6.499 1.00 9.07 ? 229 TRP A CD1 1 ATOM 1599 C CD2 . TRP A 1 202 ? -63.310 -26.584 8.293 1.00 7.20 ? 229 TRP A CD2 1 ATOM 1600 N NE1 . TRP A 1 202 ? -63.184 -24.475 7.552 1.00 8.98 ? 229 TRP A NE1 1 ATOM 1601 C CE2 . TRP A 1 202 ? -63.436 -25.233 8.664 1.00 7.13 ? 229 TRP A CE2 1 ATOM 1602 C CE3 . TRP A 1 202 ? -63.517 -27.571 9.259 1.00 7.43 ? 229 TRP A CE3 1 ATOM 1603 C CZ2 . TRP A 1 202 ? -63.763 -24.846 9.957 1.00 6.99 ? 229 TRP A CZ2 1 ATOM 1604 C CZ3 . TRP A 1 202 ? -63.841 -27.185 10.539 1.00 7.28 ? 229 TRP A CZ3 1 ATOM 1605 C CH2 . TRP A 1 202 ? -63.961 -25.834 10.878 1.00 8.14 ? 229 TRP A CH2 1 ATOM 1606 N N . SER A 1 203 ? -64.782 -30.108 6.536 1.00 9.02 ? 230 SER A N 1 ATOM 1607 C CA . SER A 1 203 ? -65.702 -30.819 7.424 1.00 10.76 ? 230 SER A CA 1 ATOM 1608 C C . SER A 1 203 ? -67.164 -30.794 6.962 1.00 16.17 ? 230 SER A C 1 ATOM 1609 O O . SER A 1 203 ? -68.062 -30.447 7.730 1.00 16.64 ? 230 SER A O 1 ATOM 1610 C CB . SER A 1 203 ? -65.586 -30.312 8.865 1.00 11.73 ? 230 SER A CB 1 ATOM 1611 O OG . SER A 1 203 ? -64.391 -30.763 9.476 1.00 8.02 ? 230 SER A OG 1 ATOM 1612 N N . ASN A 1 204 ? -67.391 -31.153 5.701 1.00 16.54 ? 231 ASN A N 1 ATOM 1613 C CA . ASN A 1 204 ? -68.741 -31.368 5.195 1.00 13.04 ? 231 ASN A CA 1 ATOM 1614 C C . ASN A 1 204 ? -68.907 -32.805 4.716 1.00 16.87 ? 231 ASN A C 1 ATOM 1615 O O . ASN A 1 204 ? -68.513 -33.743 5.405 1.00 20.14 ? 231 ASN A O 1 ATOM 1616 C CB . ASN A 1 204 ? -69.056 -30.395 4.067 1.00 9.45 ? 231 ASN A CB 1 ATOM 1617 C CG . ASN A 1 204 ? -69.354 -29.010 4.569 1.00 8.64 ? 231 ASN A CG 1 ATOM 1618 O OD1 . ASN A 1 204 ? -70.424 -28.754 5.111 1.00 8.40 ? 231 ASN A OD1 1 ATOM 1619 N ND2 . ASN A 1 204 ? -68.412 -28.101 4.385 1.00 10.26 ? 231 ASN A ND2 1 ATOM 1620 N N . GLN A 1 205 ? -69.487 -32.971 3.531 1.00 18.34 ? 232 GLN A N 1 ATOM 1621 C CA . GLN A 1 205 ? -69.626 -34.285 2.906 1.00 15.48 ? 232 GLN A CA 1 ATOM 1622 C C . GLN A 1 205 ? -69.402 -34.184 1.397 1.00 16.70 ? 232 GLN A C 1 ATOM 1623 O O . GLN A 1 205 ? -69.754 -35.096 0.652 1.00 20.90 ? 232 GLN A O 1 ATOM 1624 C CB . GLN A 1 205 ? -71.013 -34.869 3.173 1.00 14.77 ? 232 GLN A CB 1 ATOM 1625 C CG . GLN A 1 205 ? -71.399 -34.956 4.633 1.00 17.42 ? 232 GLN A CG 1 ATOM 1626 C CD . GLN A 1 205 ? -72.761 -35.575 4.824 1.00 25.29 ? 232 GLN A CD 1 ATOM 1627 O OE1 . GLN A 1 205 ? -73.401 -35.400 5.861 1.00 25.86 ? 232 GLN A OE1 1 ATOM 1628 N NE2 . GLN A 1 205 ? -73.216 -36.311 3.816 1.00 25.91 ? 232 GLN A NE2 1 ATOM 1629 N N . LEU A 1 206 ? -68.808 -33.078 0.956 1.00 13.78 ? 233 LEU A N 1 ATOM 1630 C CA . LEU A 1 206 ? -68.650 -32.776 -0.466 1.00 12.73 ? 233 LEU A CA 1 ATOM 1631 C C . LEU A 1 206 ? -67.954 -33.858 -1.291 1.00 12.83 ? 233 LEU A C 1 ATOM 1632 O O . LEU A 1 206 ? -66.927 -33.597 -1.913 1.00 12.36 ? 233 LEU A O 1 ATOM 1633 C CB . LEU A 1 206 ? -67.893 -31.464 -0.634 1.00 10.80 ? 233 LEU A CB 1 ATOM 1634 C CG . LEU A 1 206 ? -68.574 -30.216 -0.085 1.00 12.15 ? 233 LEU A CG 1 ATOM 1635 C CD1 . LEU A 1 206 ? -67.780 -28.987 -0.489 1.00 14.03 ? 233 LEU A CD1 1 ATOM 1636 C CD2 . LEU A 1 206 ? -70.000 -30.124 -0.587 1.00 11.78 ? 233 LEU A CD2 1 ATOM 1637 N N . HIS A 1 207 ? -68.535 -35.053 -1.322 1.00 12.54 ? 234 HIS A N 1 ATOM 1638 C CA . HIS A 1 207 ? -67.924 -36.192 -1.994 1.00 15.88 ? 234 HIS A CA 1 ATOM 1639 C C . HIS A 1 207 ? -67.655 -35.961 -3.471 1.00 23.46 ? 234 HIS A C 1 ATOM 1640 O O . HIS A 1 207 ? -66.557 -35.549 -3.859 1.00 22.93 ? 234 HIS A O 1 ATOM 1641 C CB . HIS A 1 207 ? -68.784 -37.436 -1.823 1.00 16.39 ? 234 HIS A CB 1 ATOM 1642 C CG . HIS A 1 207 ? -68.706 -38.033 -0.456 1.00 21.13 ? 234 HIS A CG 1 ATOM 1643 N ND1 . HIS A 1 207 ? -68.608 -37.265 0.685 1.00 22.84 ? 234 HIS A ND1 1 ATOM 1644 C CD2 . HIS A 1 207 ? -68.707 -39.322 -0.043 1.00 28.98 ? 234 HIS A CD2 1 ATOM 1645 C CE1 . HIS A 1 207 ? -68.554 -38.056 1.743 1.00 28.41 ? 234 HIS A CE1 1 ATOM 1646 N NE2 . HIS A 1 207 ? -68.613 -39.309 1.328 1.00 38.75 ? 234 HIS A NE2 1 ATOM 1647 N N . ASN A 1 208 ? -68.660 -36.237 -4.292 1.00 26.02 ? 235 ASN A N 1 ATOM 1648 C CA . ASN A 1 208 ? -68.487 -36.189 -5.736 1.00 28.12 ? 235 ASN A CA 1 ATOM 1649 C C . ASN A 1 208 ? -68.544 -34.772 -6.293 1.00 19.71 ? 235 ASN A C 1 ATOM 1650 O O . ASN A 1 208 ? -69.497 -34.407 -6.971 1.00 33.13 ? 235 ASN A O 1 ATOM 1651 C CB . ASN A 1 208 ? -69.538 -37.059 -6.432 1.00 42.44 ? 235 ASN A CB 1 ATOM 1652 C CG . ASN A 1 208 ? -69.747 -38.395 -5.742 1.00 41.67 ? 235 ASN A CG 1 ATOM 1653 O OD1 . ASN A 1 208 ? -70.848 -38.695 -5.273 1.00 41.56 ? 235 ASN A OD1 1 ATOM 1654 N ND2 . ASN A 1 208 ? -68.697 -39.212 -5.691 1.00 41.66 ? 235 ASN A ND2 1 ATOM 1655 N N . LEU A 1 209 ? -67.531 -33.967 -6.006 1.00 15.70 ? 236 LEU A N 1 ATOM 1656 C CA . LEU A 1 209 ? -67.428 -32.673 -6.655 1.00 17.89 ? 236 LEU A CA 1 ATOM 1657 C C . LEU A 1 209 ? -67.038 -32.931 -8.092 1.00 22.55 ? 236 LEU A C 1 ATOM 1658 O O . LEU A 1 209 ? -66.583 -34.027 -8.421 1.00 24.33 ? 236 LEU A O 1 ATOM 1659 C CB . LEU A 1 209 ? -66.369 -31.794 -5.991 1.00 19.17 ? 236 LEU A CB 1 ATOM 1660 C CG . LEU A 1 209 ? -66.627 -31.298 -4.569 1.00 14.64 ? 236 LEU A CG 1 ATOM 1661 C CD1 . LEU A 1 209 ? -66.011 -29.935 -4.407 1.00 7.76 ? 236 LEU A CD1 1 ATOM 1662 C CD2 . LEU A 1 209 ? -68.115 -31.256 -4.259 1.00 19.45 ? 236 LEU A CD2 1 ATOM 1663 N N . THR A 1 210 ? -67.209 -31.931 -8.950 1.00 25.59 ? 237 THR A N 1 ATOM 1664 C CA . THR A 1 210 ? -66.825 -32.079 -10.346 1.00 22.09 ? 237 THR A CA 1 ATOM 1665 C C . THR A 1 210 ? -66.645 -30.739 -11.057 1.00 20.41 ? 237 THR A C 1 ATOM 1666 O O . THR A 1 210 ? -67.218 -29.731 -10.641 1.00 18.02 ? 237 THR A O 1 ATOM 1667 C CB . THR A 1 210 ? -67.835 -32.936 -11.103 1.00 18.79 ? 237 THR A CB 1 ATOM 1668 O OG1 . THR A 1 210 ? -67.262 -33.353 -12.349 1.00 30.53 ? 237 THR A OG1 1 ATOM 1669 C CG2 . THR A 1 210 ? -69.115 -32.151 -11.344 1.00 25.96 ? 237 THR A CG2 1 ATOM 1670 N N . LYS A 1 211 ? -65.844 -30.760 -12.127 1.00 18.57 ? 238 LYS A N 1 ATOM 1671 C CA . LYS A 1 211 ? -65.483 -29.587 -12.938 1.00 17.89 ? 238 LYS A CA 1 ATOM 1672 C C . LYS A 1 211 ? -66.583 -28.545 -13.078 1.00 22.52 ? 238 LYS A C 1 ATOM 1673 O O . LYS A 1 211 ? -66.314 -27.345 -13.153 1.00 21.76 ? 238 LYS A O 1 ATOM 1674 C CB . LYS A 1 211 ? -65.024 -30.042 -14.330 1.00 20.06 ? 238 LYS A CB 1 ATOM 1675 C CG . LYS A 1 211 ? -64.969 -28.950 -15.403 1.00 18.57 ? 238 LYS A CG 1 ATOM 1676 C CD . LYS A 1 211 ? -64.332 -29.477 -16.693 1.00 17.82 ? 238 LYS A CD 1 ATOM 1677 C CE . LYS A 1 211 ? -64.596 -28.568 -17.896 1.00 21.29 ? 238 LYS A CE 1 ATOM 1678 N NZ . LYS A 1 211 ? -63.670 -27.401 -18.023 1.00 14.75 1 238 LYS A NZ 1 ATOM 1679 N N . HIS A 1 212 ? -67.825 -29.015 -13.100 1.00 29.06 ? 239 HIS A N 1 ATOM 1680 C CA . HIS A 1 212 ? -68.974 -28.136 -13.226 1.00 32.09 ? 239 HIS A CA 1 ATOM 1681 C C . HIS A 1 212 ? -69.215 -27.344 -11.945 1.00 31.07 ? 239 HIS A C 1 ATOM 1682 O O . HIS A 1 212 ? -69.721 -26.225 -11.991 1.00 35.57 ? 239 HIS A O 1 ATOM 1683 C CB . HIS A 1 212 ? -70.223 -28.943 -13.590 1.00 39.83 ? 239 HIS A CB 1 ATOM 1684 C CG . HIS A 1 212 ? -71.353 -28.103 -14.102 1.00 54.98 ? 239 HIS A CG 1 ATOM 1685 N ND1 . HIS A 1 212 ? -72.617 -28.607 -14.319 1.00 57.78 ? 239 HIS A ND1 1 ATOM 1686 C CD2 . HIS A 1 212 ? -71.406 -26.794 -14.444 1.00 46.32 ? 239 HIS A CD2 1 ATOM 1687 C CE1 . HIS A 1 212 ? -73.402 -27.643 -14.766 1.00 57.68 ? 239 HIS A CE1 1 ATOM 1688 N NE2 . HIS A 1 212 ? -72.691 -26.533 -14.851 1.00 45.40 ? 239 HIS A NE2 1 ATOM 1689 N N . ASP A 1 213 ? -68.837 -27.916 -10.806 1.00 30.71 ? 240 ASP A N 1 ATOM 1690 C CA . ASP A 1 213 ? -69.115 -27.289 -9.513 1.00 25.59 ? 240 ASP A CA 1 ATOM 1691 C C . ASP A 1 213 ? -68.370 -25.974 -9.266 1.00 19.65 ? 240 ASP A C 1 ATOM 1692 O O . ASP A 1 213 ? -68.678 -25.256 -8.320 1.00 17.49 ? 240 ASP A O 1 ATOM 1693 C CB . ASP A 1 213 ? -68.869 -28.271 -8.363 1.00 20.38 ? 240 ASP A CB 1 ATOM 1694 C CG . ASP A 1 213 ? -70.020 -29.244 -8.173 1.00 29.43 ? 240 ASP A CG 1 ATOM 1695 O OD1 . ASP A 1 213 ? -71.108 -28.990 -8.733 1.00 39.47 ? 240 ASP A OD1 1 ATOM 1696 O OD2 . ASP A 1 213 ? -69.848 -30.255 -7.458 1.00 27.09 1 240 ASP A OD2 1 ATOM 1697 N N . PHE A 1 214 ? -67.409 -25.645 -10.120 1.00 19.32 ? 241 PHE A N 1 ATOM 1698 C CA . PHE A 1 214 ? -66.610 -24.444 -9.905 1.00 19.47 ? 241 PHE A CA 1 ATOM 1699 C C . PHE A 1 214 ? -66.638 -23.472 -11.072 1.00 23.76 ? 241 PHE A C 1 ATOM 1700 O O . PHE A 1 214 ? -65.826 -22.551 -11.146 1.00 20.78 ? 241 PHE A O 1 ATOM 1701 C CB . PHE A 1 214 ? -65.178 -24.830 -9.549 1.00 17.04 ? 241 PHE A CB 1 ATOM 1702 C CG . PHE A 1 214 ? -65.080 -25.567 -8.261 1.00 15.26 ? 241 PHE A CG 1 ATOM 1703 C CD1 . PHE A 1 214 ? -65.051 -24.878 -7.060 1.00 12.70 ? 241 PHE A CD1 1 ATOM 1704 C CD2 . PHE A 1 214 ? -65.063 -26.948 -8.239 1.00 15.85 ? 241 PHE A CD2 1 ATOM 1705 C CE1 . PHE A 1 214 ? -64.985 -25.549 -5.864 1.00 9.79 ? 241 PHE A CE1 1 ATOM 1706 C CE2 . PHE A 1 214 ? -64.994 -27.628 -7.041 1.00 16.26 ? 241 PHE A CE2 1 ATOM 1707 C CZ . PHE A 1 214 ? -64.957 -26.925 -5.852 1.00 11.55 ? 241 PHE A CZ 1 ATOM 1708 N N . GLU A 1 215 ? -67.595 -23.677 -11.970 1.00 26.38 ? 242 GLU A N 1 ATOM 1709 C CA . GLU A 1 215 ? -67.751 -22.837 -13.148 1.00 26.02 ? 242 GLU A CA 1 ATOM 1710 C C . GLU A 1 215 ? -68.047 -21.387 -12.782 1.00 18.11 ? 242 GLU A C 1 ATOM 1711 O O . GLU A 1 215 ? -69.079 -21.090 -12.196 1.00 17.88 ? 242 GLU A O 1 ATOM 1712 C CB . GLU A 1 215 ? -68.875 -23.391 -14.021 1.00 34.77 ? 242 GLU A CB 1 ATOM 1713 C CG . GLU A 1 215 ? -68.768 -23.032 -15.490 1.00 46.19 ? 242 GLU A CG 1 ATOM 1714 C CD . GLU A 1 215 ? -69.980 -23.481 -16.279 1.00 52.17 ? 242 GLU A CD 1 ATOM 1715 O OE1 . GLU A 1 215 ? -69.797 -24.048 -17.379 1.00 58.37 ? 242 GLU A OE1 1 ATOM 1716 O OE2 . GLU A 1 215 ? -71.115 -23.265 -15.795 1.00 47.64 1 242 GLU A OE2 1 ATOM 1717 N N . GLY A 1 216 ? -67.137 -20.488 -13.134 1.00 15.35 ? 243 GLY A N 1 ATOM 1718 C CA . GLY A 1 216 ? -67.330 -19.079 -12.855 1.00 16.25 ? 243 GLY A CA 1 ATOM 1719 C C . GLY A 1 216 ? -66.525 -18.610 -11.661 1.00 23.03 ? 243 GLY A C 1 ATOM 1720 O O . GLY A 1 216 ? -66.528 -17.425 -11.320 1.00 22.85 ? 243 GLY A O 1 ATOM 1721 N N . ALA A 1 217 ? -65.827 -19.546 -11.023 1.00 27.79 ? 244 ALA A N 1 ATOM 1722 C CA . ALA A 1 217 ? -64.996 -19.230 -9.863 1.00 25.03 ? 244 ALA A CA 1 ATOM 1723 C C . ALA A 1 217 ? -63.567 -18.837 -10.256 1.00 23.18 ? 244 ALA A C 1 ATOM 1724 O O . ALA A 1 217 ? -62.594 -19.401 -9.748 1.00 21.78 ? 244 ALA A O 1 ATOM 1725 C CB . ALA A 1 217 ? -64.980 -20.402 -8.882 1.00 17.54 ? 244 ALA A CB 1 ATOM 1726 N N . THR A 1 218 ? -63.443 -17.872 -11.161 1.00 20.58 ? 245 THR A N 1 ATOM 1727 C CA . THR A 1 218 ? -62.130 -17.366 -11.534 1.00 21.69 ? 245 THR A CA 1 ATOM 1728 C C . THR A 1 218 ? -61.780 -16.191 -10.639 1.00 20.53 ? 245 THR A C 1 ATOM 1729 O O . THR A 1 218 ? -60.783 -15.508 -10.848 1.00 26.94 ? 245 THR A O 1 ATOM 1730 C CB . THR A 1 218 ? -62.075 -16.915 -12.998 1.00 24.00 ? 245 THR A CB 1 ATOM 1731 O OG1 . THR A 1 218 ? -62.890 -15.749 -13.169 1.00 28.71 ? 245 THR A OG1 1 ATOM 1732 C CG2 . THR A 1 218 ? -62.557 -18.032 -13.919 1.00 25.91 ? 245 THR A CG2 1 ATOM 1733 N N . SER A 1 219 ? -62.623 -15.955 -9.645 1.00 19.07 ? 246 SER A N 1 ATOM 1734 C CA . SER A 1 219 ? -62.366 -14.933 -8.645 1.00 17.42 ? 246 SER A CA 1 ATOM 1735 C C . SER A 1 219 ? -61.711 -15.584 -7.436 1.00 14.14 ? 246 SER A C 1 ATOM 1736 O O . SER A 1 219 ? -61.010 -14.928 -6.675 1.00 12.98 ? 246 SER A O 1 ATOM 1737 C CB . SER A 1 219 ? -63.681 -14.238 -8.256 1.00 21.11 ? 246 SER A CB 1 ATOM 1738 O OG . SER A 1 219 ? -63.776 -14.000 -6.858 1.00 14.49 ? 246 SER A OG 1 ATOM 1739 N N . VAL A 1 220 ? -61.930 -16.889 -7.292 1.00 15.18 ? 247 VAL A N 1 ATOM 1740 C CA . VAL A 1 220 ? -61.511 -17.652 -6.116 1.00 12.65 ? 247 VAL A CA 1 ATOM 1741 C C . VAL A 1 220 ? -60.003 -17.924 -6.048 1.00 16.00 ? 247 VAL A C 1 ATOM 1742 O O . VAL A 1 220 ? -59.392 -18.403 -7.008 1.00 16.90 ? 247 VAL A O 1 ATOM 1743 C CB . VAL A 1 220 ? -62.285 -18.988 -6.027 1.00 11.17 ? 247 VAL A CB 1 ATOM 1744 C CG1 . VAL A 1 220 ? -61.704 -19.882 -4.954 1.00 10.77 ? 247 VAL A CG1 1 ATOM 1745 C CG2 . VAL A 1 220 ? -63.752 -18.728 -5.765 1.00 11.38 ? 247 VAL A CG2 1 ATOM 1746 N N . LEU A 1 221 ? -59.418 -17.613 -4.894 1.00 14.33 ? 248 LEU A N 1 ATOM 1747 C CA . LEU A 1 221 ? -57.997 -17.797 -4.656 1.00 11.08 ? 248 LEU A CA 1 ATOM 1748 C C . LEU A 1 221 ? -57.754 -19.025 -3.799 1.00 13.96 ? 248 LEU A C 1 ATOM 1749 O O . LEU A 1 221 ? -56.944 -19.874 -4.147 1.00 15.67 ? 248 LEU A O 1 ATOM 1750 C CB . LEU A 1 221 ? -57.432 -16.575 -3.946 1.00 9.18 ? 248 LEU A CB 1 ATOM 1751 C CG . LEU A 1 221 ? -57.558 -15.284 -4.740 1.00 8.25 ? 248 LEU A CG 1 ATOM 1752 C CD1 . LEU A 1 221 ? -57.021 -14.124 -3.936 1.00 9.08 ? 248 LEU A CD1 1 ATOM 1753 C CD2 . LEU A 1 221 ? -56.833 -15.413 -6.072 1.00 6.98 ? 248 LEU A CD2 1 ATOM 1754 N N . GLY A 1 222 ? -58.454 -19.110 -2.671 1.00 14.26 ? 249 GLY A N 1 ATOM 1755 C CA . GLY A 1 222 ? -58.294 -20.227 -1.756 1.00 12.15 ? 249 GLY A CA 1 ATOM 1756 C C . GLY A 1 222 ? -59.537 -21.083 -1.582 1.00 10.26 ? 249 GLY A C 1 ATOM 1757 O O . GLY A 1 222 ? -60.616 -20.581 -1.273 1.00 10.13 ? 249 GLY A O 1 ATOM 1758 N N . ILE A 1 223 ? -59.381 -22.386 -1.780 1.00 8.36 ? 250 ILE A N 1 ATOM 1759 C CA . ILE A 1 223 ? -60.478 -23.323 -1.578 1.00 8.15 ? 250 ILE A CA 1 ATOM 1760 C C . ILE A 1 223 ? -60.067 -24.474 -0.663 1.00 10.04 ? 250 ILE A C 1 ATOM 1761 O O . ILE A 1 223 ? -59.204 -25.280 -1.007 1.00 11.11 ? 250 ILE A O 1 ATOM 1762 C CB . ILE A 1 223 ? -60.970 -23.894 -2.909 1.00 8.55 ? 250 ILE A CB 1 ATOM 1763 C CG1 . ILE A 1 223 ? -61.822 -25.143 -2.664 1.00 9.58 ? 250 ILE A CG1 1 ATOM 1764 C CG2 . ILE A 1 223 ? -59.792 -24.201 -3.814 1.00 9.01 ? 250 ILE A CG2 1 ATOM 1765 C CD1 . ILE A 1 223 ? -61.889 -26.093 -3.846 1.00 11.22 ? 250 ILE A CD1 1 ATOM 1766 N N . ASP A 1 224 ? -60.682 -24.547 0.511 1.00 10.20 ? 251 ASP A N 1 ATOM 1767 C CA . ASP A 1 224 ? -60.372 -25.611 1.454 1.00 8.63 ? 251 ASP A CA 1 ATOM 1768 C C . ASP A 1 224 ? -61.481 -26.650 1.427 1.00 8.81 ? 251 ASP A C 1 ATOM 1769 O O . ASP A 1 224 ? -62.648 -26.325 1.636 1.00 9.71 ? 251 ASP A O 1 ATOM 1770 C CB . ASP A 1 224 ? -60.209 -25.043 2.866 1.00 8.81 ? 251 ASP A CB 1 ATOM 1771 C CG . ASP A 1 224 ? -59.603 -26.044 3.838 1.00 9.09 ? 251 ASP A CG 1 ATOM 1772 O OD1 . ASP A 1 224 ? -59.698 -27.265 3.589 1.00 8.32 ? 251 ASP A OD1 1 ATOM 1773 O OD2 . ASP A 1 224 ? -59.030 -25.611 4.863 1.00 10.26 1 251 ASP A OD2 1 ATOM 1774 N N . ILE A 1 225 ? -61.116 -27.900 1.166 1.00 7.64 ? 252 ILE A N 1 ATOM 1775 C CA . ILE A 1 225 ? -62.086 -28.992 1.200 1.00 9.52 ? 252 ILE A CA 1 ATOM 1776 C C . ILE A 1 225 ? -61.594 -30.146 2.076 1.00 9.52 ? 252 ILE A C 1 ATOM 1777 O O . ILE A 1 225 ? -61.959 -31.306 1.864 1.00 9.15 ? 252 ILE A O 1 ATOM 1778 C CB . ILE A 1 225 ? -62.456 -29.515 -0.228 1.00 9.53 ? 252 ILE A CB 1 ATOM 1779 C CG1 . ILE A 1 225 ? -61.231 -30.087 -0.946 1.00 8.22 ? 252 ILE A CG1 1 ATOM 1780 C CG2 . ILE A 1 225 ? -63.120 -28.423 -1.063 1.00 6.59 ? 252 ILE A CG2 1 ATOM 1781 C CD1 . ILE A 1 225 ? -61.507 -30.532 -2.353 1.00 5.68 ? 252 ILE A CD1 1 ATOM 1782 N N . HIS A 1 226 ? -60.765 -29.827 3.065 1.00 10.31 ? 253 HIS A N 1 ATOM 1783 C CA . HIS A 1 226 ? -60.212 -30.869 3.924 1.00 10.32 ? 253 HIS A CA 1 ATOM 1784 C C . HIS A 1 226 ? -61.297 -31.470 4.803 1.00 11.03 ? 253 HIS A C 1 ATOM 1785 O O . HIS A 1 226 ? -62.358 -30.870 4.966 1.00 11.21 ? 253 HIS A O 1 ATOM 1786 C CB . HIS A 1 226 ? -59.015 -30.368 4.746 1.00 8.75 ? 253 HIS A CB 1 ATOM 1787 C CG . HIS A 1 226 ? -59.383 -29.592 5.973 1.00 7.84 ? 253 HIS A CG 1 ATOM 1788 N ND1 . HIS A 1 226 ? -59.296 -28.219 6.036 1.00 7.47 ? 253 HIS A ND1 1 ATOM 1789 C CD2 . HIS A 1 226 ? -59.796 -30.000 7.196 1.00 8.73 ? 253 HIS A CD2 1 ATOM 1790 C CE1 . HIS A 1 226 ? -59.656 -27.812 7.240 1.00 8.79 ? 253 HIS A CE1 1 ATOM 1791 N NE2 . HIS A 1 226 ? -59.969 -28.873 7.962 1.00 9.11 ? 253 HIS A NE2 1 ATOM 1792 N N . ASP A 1 227 ? -61.033 -32.654 5.351 1.00 10.77 ? 254 ASP A N 1 ATOM 1793 C CA . ASP A 1 227 ? -62.042 -33.401 6.099 1.00 10.47 ? 254 ASP A CA 1 ATOM 1794 C C . ASP A 1 227 ? -63.315 -33.489 5.279 1.00 13.51 ? 254 ASP A C 1 ATOM 1795 O O . ASP A 1 227 ? -64.327 -32.905 5.645 1.00 16.98 ? 254 ASP A O 1 ATOM 1796 C CB . ASP A 1 227 ? -62.336 -32.730 7.445 1.00 11.20 ? 254 ASP A CB 1 ATOM 1797 C CG . ASP A 1 227 ? -63.361 -33.487 8.264 1.00 10.39 ? 254 ASP A CG 1 ATOM 1798 O OD1 . ASP A 1 227 ? -63.409 -34.728 8.149 1.00 10.95 ? 254 ASP A OD1 1 ATOM 1799 O OD2 . ASP A 1 227 ? -64.123 -32.840 9.012 1.00 9.87 1 254 ASP A OD2 1 ATOM 1800 N N . ASN A 1 228 ? -63.256 -34.180 4.144 1.00 17.22 ? 255 ASN A N 1 ATOM 1801 C CA . ASN A 1 228 ? -64.428 -34.304 3.277 1.00 17.04 ? 255 ASN A CA 1 ATOM 1802 C C . ASN A 1 228 ? -64.553 -35.668 2.608 1.00 19.85 ? 255 ASN A C 1 ATOM 1803 O O . ASN A 1 228 ? -65.107 -35.787 1.513 1.00 16.74 ? 255 ASN A O 1 ATOM 1804 C CB . ASN A 1 228 ? -64.461 -33.189 2.232 1.00 11.13 ? 255 ASN A CB 1 ATOM 1805 C CG . ASN A 1 228 ? -65.484 -32.123 2.559 1.00 11.72 ? 255 ASN A CG 1 ATOM 1806 O OD1 . ASN A 1 228 ? -66.563 -32.421 3.057 1.00 10.88 ? 255 ASN A OD1 1 ATOM 1807 N ND2 . ASN A 1 228 ? -65.147 -30.875 2.287 1.00 13.82 ? 255 ASN A ND2 1 ATOM 1808 N N . GLY A 1 229 ? -64.012 -36.690 3.267 1.00 21.97 ? 256 GLY A N 1 ATOM 1809 C CA . GLY A 1 229 ? -64.163 -38.070 2.835 1.00 21.47 ? 256 GLY A CA 1 ATOM 1810 C C . GLY A 1 229 ? -63.855 -38.384 1.382 1.00 19.93 ? 256 GLY A C 1 ATOM 1811 O O . GLY A 1 229 ? -64.018 -39.522 0.955 1.00 25.91 ? 256 GLY A O 1 ATOM 1812 N N . ILE A 1 230 ? -63.415 -37.378 0.633 1.00 14.76 ? 257 ILE A N 1 ATOM 1813 C CA . ILE A 1 230 ? -63.095 -37.513 -0.780 1.00 12.90 ? 257 ILE A CA 1 ATOM 1814 C C . ILE A 1 230 ? -62.191 -38.712 -1.089 1.00 17.35 ? 257 ILE A C 1 ATOM 1815 O O . ILE A 1 230 ? -61.007 -38.730 -0.750 1.00 15.82 ? 257 ILE A O 1 ATOM 1816 C CB . ILE A 1 230 ? -62.454 -36.227 -1.301 1.00 12.78 ? 257 ILE A CB 1 ATOM 1817 C CG1 . ILE A 1 230 ? -63.409 -35.057 -1.086 1.00 10.36 ? 257 ILE A CG1 1 ATOM 1818 C CG2 . ILE A 1 230 ? -62.072 -36.368 -2.767 1.00 16.09 ? 257 ILE A CG2 1 ATOM 1819 C CD1 . ILE A 1 230 ? -62.779 -33.717 -1.324 1.00 11.03 ? 257 ILE A CD1 1 ATOM 1820 N N . GLU A 1 231 ? -62.781 -39.711 -1.735 1.00 18.89 ? 258 GLU A N 1 ATOM 1821 C CA . GLU A 1 231 ? -62.089 -40.932 -2.104 1.00 14.19 ? 258 GLU A CA 1 ATOM 1822 C C . GLU A 1 231 ? -61.246 -40.720 -3.355 1.00 19.84 ? 258 GLU A C 1 ATOM 1823 O O . GLU A 1 231 ? -60.175 -41.305 -3.485 1.00 29.67 ? 258 GLU A O 1 ATOM 1824 C CB . GLU A 1 231 ? -63.101 -42.048 -2.342 1.00 12.33 ? 258 GLU A CB 1 ATOM 1825 C CG . GLU A 1 231 ? -62.796 -43.325 -1.604 1.00 14.58 ? 258 GLU A CG 1 ATOM 1826 C CD . GLU A 1 231 ? -64.000 -43.857 -0.878 1.00 15.24 ? 258 GLU A CD 1 ATOM 1827 O OE1 . GLU A 1 231 ? -63.849 -44.792 -0.061 1.00 14.96 ? 258 GLU A OE1 1 ATOM 1828 O OE2 . GLU A 1 231 ? -65.102 -43.330 -1.122 1.00 19.42 1 258 GLU A OE2 1 ATOM 1829 N N . GLN A 1 232 ? -61.734 -39.888 -4.273 1.00 19.92 ? 259 GLN A N 1 ATOM 1830 C CA . GLN A 1 232 ? -60.994 -39.555 -5.492 1.00 23.52 ? 259 GLN A CA 1 ATOM 1831 C C . GLN A 1 232 ? -61.618 -38.383 -6.258 1.00 22.98 ? 259 GLN A C 1 ATOM 1832 O O . GLN A 1 232 ? -62.833 -38.187 -6.231 1.00 23.41 ? 259 GLN A O 1 ATOM 1833 C CB . GLN A 1 232 ? -60.860 -40.777 -6.403 1.00 23.18 ? 259 GLN A CB 1 ATOM 1834 C CG . GLN A 1 232 ? -62.180 -41.409 -6.797 1.00 32.38 ? 259 GLN A CG 1 ATOM 1835 C CD . GLN A 1 232 ? -61.993 -42.685 -7.596 1.00 49.57 ? 259 GLN A CD 1 ATOM 1836 O OE1 . GLN A 1 232 ? -61.030 -43.425 -7.386 1.00 55.57 ? 259 GLN A OE1 1 ATOM 1837 N NE2 . GLN A 1 232 ? -62.910 -42.945 -8.523 1.00 52.68 ? 259 GLN A NE2 1 ATOM 1838 N N . LEU A 1 233 ? -60.773 -37.610 -6.935 1.00 19.26 ? 260 LEU A N 1 ATOM 1839 C CA . LEU A 1 233 ? -61.216 -36.430 -7.664 1.00 16.69 ? 260 LEU A CA 1 ATOM 1840 C C . LEU A 1 233 ? -61.028 -36.603 -9.159 1.00 22.09 ? 260 LEU A C 1 ATOM 1841 O O . LEU A 1 233 ? -60.024 -37.165 -9.603 1.00 18.90 ? 260 LEU A O 1 ATOM 1842 C CB . LEU A 1 233 ? -60.437 -35.186 -7.224 1.00 17.31 ? 260 LEU A CB 1 ATOM 1843 C CG . LEU A 1 233 ? -60.646 -34.562 -5.843 1.00 15.05 ? 260 LEU A CG 1 ATOM 1844 C CD1 . LEU A 1 233 ? -59.726 -33.369 -5.698 1.00 14.88 ? 260 LEU A CD1 1 ATOM 1845 C CD2 . LEU A 1 233 ? -62.082 -34.135 -5.642 1.00 15.83 ? 260 LEU A CD2 1 ATOM 1846 N N . PRO A 1 234 ? -62.012 -36.131 -9.942 1.00 28.24 ? 261 PRO A N 1 ATOM 1847 C CA . PRO A 1 234 ? -61.857 -35.955 -11.388 1.00 25.13 ? 261 PRO A CA 1 ATOM 1848 C C . PRO A 1 234 ? -60.690 -35.022 -11.706 1.00 24.71 ? 261 PRO A C 1 ATOM 1849 O O . PRO A 1 234 ? -60.492 -34.024 -11.018 1.00 26.71 ? 261 PRO A O 1 ATOM 1850 C CB . PRO A 1 234 ? -63.180 -35.310 -11.791 1.00 22.33 ? 261 PRO A CB 1 ATOM 1851 C CG . PRO A 1 234 ? -64.161 -35.881 -10.825 1.00 19.96 ? 261 PRO A CG 1 ATOM 1852 C CD . PRO A 1 234 ? -63.420 -35.999 -9.522 1.00 21.10 ? 261 PRO A CD 1 ATOM 1853 N N . HIS A 1 235 ? -59.935 -35.341 -12.751 1.00 23.27 ? 262 HIS A N 1 ATOM 1854 C CA . HIS A 1 235 ? -58.726 -34.596 -13.096 1.00 24.09 ? 262 HIS A CA 1 ATOM 1855 C C . HIS A 1 235 ? -58.962 -33.160 -13.571 1.00 23.62 ? 262 HIS A C 1 ATOM 1856 O O . HIS A 1 235 ? -58.048 -32.513 -14.089 1.00 21.88 ? 262 HIS A O 1 ATOM 1857 C CB . HIS A 1 235 ? -57.976 -35.341 -14.191 1.00 26.40 ? 262 HIS A CB 1 ATOM 1858 C CG . HIS A 1 235 ? -58.653 -35.281 -15.523 1.00 20.82 ? 262 HIS A CG 1 ATOM 1859 N ND1 . HIS A 1 235 ? -58.606 -34.167 -16.332 1.00 20.30 ? 262 HIS A ND1 1 ATOM 1860 C CD2 . HIS A 1 235 ? -59.399 -36.196 -16.184 1.00 18.27 ? 262 HIS A CD2 1 ATOM 1861 C CE1 . HIS A 1 235 ? -59.289 -34.400 -17.437 1.00 22.00 ? 262 HIS A CE1 1 ATOM 1862 N NE2 . HIS A 1 235 ? -59.779 -35.624 -17.373 1.00 20.81 ? 262 HIS A NE2 1 ATOM 1863 N N . ASP A 1 236 ? -60.182 -32.666 -13.426 1.00 23.41 ? 263 ASP A N 1 ATOM 1864 C CA . ASP A 1 236 ? -60.496 -31.327 -13.896 1.00 23.63 ? 263 ASP A CA 1 ATOM 1865 C C . ASP A 1 236 ? -61.370 -30.588 -12.900 1.00 23.92 ? 263 ASP A C 1 ATOM 1866 O O . ASP A 1 236 ? -61.930 -29.543 -13.223 1.00 21.31 ? 263 ASP A O 1 ATOM 1867 C CB . ASP A 1 236 ? -61.186 -31.387 -15.258 1.00 23.03 ? 263 ASP A CB 1 ATOM 1868 C CG . ASP A 1 236 ? -62.194 -32.514 -15.348 1.00 24.84 ? 263 ASP A CG 1 ATOM 1869 O OD1 . ASP A 1 236 ? -62.491 -33.126 -14.300 1.00 23.46 ? 263 ASP A OD1 1 ATOM 1870 O OD2 . ASP A 1 236 ? -62.693 -32.786 -16.463 1.00 27.07 1 263 ASP A OD2 1 ATOM 1871 N N . VAL A 1 237 ? -61.482 -31.137 -11.693 1.00 25.88 ? 264 VAL A N 1 ATOM 1872 C CA . VAL A 1 237 ? -62.308 -30.542 -10.646 1.00 22.71 ? 264 VAL A CA 1 ATOM 1873 C C . VAL A 1 237 ? -61.987 -29.069 -10.487 1.00 21.15 ? 264 VAL A C 1 ATOM 1874 O O . VAL A 1 237 ? -62.882 -28.235 -10.331 1.00 18.95 ? 264 VAL A O 1 ATOM 1875 C CB . VAL A 1 237 ? -62.091 -31.233 -9.291 1.00 22.24 ? 264 VAL A CB 1 ATOM 1876 C CG1 . VAL A 1 237 ? -62.739 -30.431 -8.180 1.00 23.07 ? 264 VAL A CG1 1 ATOM 1877 C CG2 . VAL A 1 237 ? -62.660 -32.629 -9.317 1.00 23.51 ? 264 VAL A CG2 1 ATOM 1878 N N . PHE A 1 238 ? -60.698 -28.758 -10.568 1.00 22.08 ? 265 PHE A N 1 ATOM 1879 C CA . PHE A 1 238 ? -60.221 -27.399 -10.367 1.00 21.32 ? 265 PHE A CA 1 ATOM 1880 C C . PHE A 1 238 ? -60.053 -26.648 -11.684 1.00 18.18 ? 265 PHE A C 1 ATOM 1881 O O . PHE A 1 238 ? -59.580 -25.514 -11.686 1.00 16.23 ? 265 PHE A O 1 ATOM 1882 C CB . PHE A 1 238 ? -58.889 -27.420 -9.612 1.00 19.19 ? 265 PHE A CB 1 ATOM 1883 C CG . PHE A 1 238 ? -58.894 -28.299 -8.388 1.00 20.80 ? 265 PHE A CG 1 ATOM 1884 C CD1 . PHE A 1 238 ? -59.977 -28.304 -7.520 1.00 17.60 ? 265 PHE A CD1 1 ATOM 1885 C CD2 . PHE A 1 238 ? -57.814 -29.129 -8.109 1.00 19.39 ? 265 PHE A CD2 1 ATOM 1886 C CE1 . PHE A 1 238 ? -59.980 -29.118 -6.397 1.00 18.86 ? 265 PHE A CE1 1 ATOM 1887 C CE2 . PHE A 1 238 ? -57.811 -29.946 -6.990 1.00 14.27 ? 265 PHE A CE2 1 ATOM 1888 C CZ . PHE A 1 238 ? -58.895 -29.941 -6.133 1.00 15.23 ? 265 PHE A CZ 1 ATOM 1889 N N . ALA A 1 239 ? -60.454 -27.270 -12.794 1.00 17.06 ? 266 ALA A N 1 ATOM 1890 C CA . ALA A 1 239 ? -60.164 -26.732 -14.127 1.00 19.05 ? 266 ALA A CA 1 ATOM 1891 C C . ALA A 1 239 ? -60.722 -25.333 -14.361 1.00 16.01 ? 266 ALA A C 1 ATOM 1892 O O . ALA A 1 239 ? -60.212 -24.585 -15.197 1.00 14.73 ? 266 ALA A O 1 ATOM 1893 C CB . ALA A 1 239 ? -60.641 -27.684 -15.213 1.00 17.66 ? 266 ALA A CB 1 ATOM 1894 N N . HIS A 1 240 ? -61.765 -24.988 -13.617 1.00 14.76 ? 267 HIS A N 1 ATOM 1895 C CA . HIS A 1 240 ? -62.356 -23.662 -13.700 1.00 18.67 ? 267 HIS A CA 1 ATOM 1896 C C . HIS A 1 240 ? -61.716 -22.720 -12.684 1.00 17.47 ? 267 HIS A C 1 ATOM 1897 O O . HIS A 1 240 ? -61.877 -21.501 -12.759 1.00 18.69 ? 267 HIS A O 1 ATOM 1898 C CB . HIS A 1 240 ? -63.874 -23.733 -13.493 1.00 21.96 ? 267 HIS A CB 1 ATOM 1899 C CG . HIS A 1 240 ? -64.625 -24.237 -14.688 1.00 22.24 ? 267 HIS A CG 1 ATOM 1900 N ND1 . HIS A 1 240 ? -64.152 -24.102 -15.975 1.00 21.84 ? 267 HIS A ND1 1 ATOM 1901 C CD2 . HIS A 1 240 ? -65.811 -24.882 -14.789 1.00 24.05 ? 267 HIS A CD2 1 ATOM 1902 C CE1 . HIS A 1 240 ? -65.016 -24.638 -16.818 1.00 23.99 ? 267 HIS A CE1 1 ATOM 1903 N NE2 . HIS A 1 240 ? -66.034 -25.114 -16.124 1.00 27.29 ? 267 HIS A NE2 1 ATOM 1904 N N . LEU A 1 241 ? -60.988 -23.293 -11.734 1.00 17.98 ? 268 LEU A N 1 ATOM 1905 C CA . LEU A 1 241 ? -60.307 -22.507 -10.713 1.00 21.06 ? 268 LEU A CA 1 ATOM 1906 C C . LEU A 1 241 ? -58.951 -22.038 -11.232 1.00 20.55 ? 268 LEU A C 1 ATOM 1907 O O . LEU A 1 241 ? -57.914 -22.478 -10.738 1.00 20.15 ? 268 LEU A O 1 ATOM 1908 C CB . LEU A 1 241 ? -60.111 -23.349 -9.448 1.00 18.56 ? 268 LEU A CB 1 ATOM 1909 C CG . LEU A 1 241 ? -61.352 -23.774 -8.659 1.00 15.28 ? 268 LEU A CG 1 ATOM 1910 C CD1 . LEU A 1 241 ? -61.017 -24.869 -7.652 1.00 12.95 ? 268 LEU A CD1 1 ATOM 1911 C CD2 . LEU A 1 241 ? -61.947 -22.573 -7.953 1.00 15.58 ? 268 LEU A CD2 1 ATOM 1912 N N . THR A 1 242 ? -58.952 -21.145 -12.218 1.00 18.16 ? 269 THR A N 1 ATOM 1913 C CA . THR A 1 242 ? -57.711 -20.820 -12.923 1.00 23.10 ? 269 THR A CA 1 ATOM 1914 C C . THR A 1 242 ? -56.692 -19.988 -12.127 1.00 25.97 ? 269 THR A C 1 ATOM 1915 O O . THR A 1 242 ? -55.483 -20.133 -12.327 1.00 26.59 ? 269 THR A O 1 ATOM 1916 C CB . THR A 1 242 ? -57.970 -20.193 -14.316 1.00 20.18 ? 269 THR A CB 1 ATOM 1917 O OG1 . THR A 1 242 ? -58.647 -18.941 -14.172 1.00 22.38 ? 269 THR A OG1 1 ATOM 1918 C CG2 . THR A 1 242 ? -58.801 -21.132 -15.176 1.00 15.19 ? 269 THR A CG2 1 ATOM 1919 N N . ASN A 1 243 ? -57.166 -19.131 -11.228 1.00 20.03 ? 270 ASN A N 1 ATOM 1920 C CA . ASN A 1 243 ? -56.253 -18.317 -10.431 1.00 21.70 ? 270 ASN A CA 1 ATOM 1921 C C . ASN A 1 243 ? -56.236 -18.729 -8.963 1.00 24.44 ? 270 ASN A C 1 ATOM 1922 O O . ASN A 1 243 ? -55.976 -17.911 -8.076 1.00 23.02 ? 270 ASN A O 1 ATOM 1923 C CB . ASN A 1 243 ? -56.597 -16.840 -10.578 1.00 20.60 ? 270 ASN A CB 1 ATOM 1924 C CG . ASN A 1 243 ? -57.409 -16.577 -11.804 1.00 22.88 ? 270 ASN A CG 1 ATOM 1925 O OD1 . ASN A 1 243 ? -58.237 -17.398 -12.177 1.00 27.97 ? 270 ASN A OD1 1 ATOM 1926 N ND2 . ASN A 1 243 ? -57.170 -15.451 -12.458 1.00 27.56 ? 270 ASN A ND2 1 ATOM 1927 N N . VAL A 1 244 ? -56.513 -20.006 -8.716 1.00 22.32 ? 271 VAL A N 1 ATOM 1928 C CA . VAL A 1 244 ? -56.509 -20.544 -7.362 1.00 17.67 ? 271 VAL A CA 1 ATOM 1929 C C . VAL A 1 244 ? -55.060 -20.608 -6.869 1.00 17.97 ? 271 VAL A C 1 ATOM 1930 O O . VAL A 1 244 ? -54.140 -20.861 -7.651 1.00 18.64 ? 271 VAL A O 1 ATOM 1931 C CB . VAL A 1 244 ? -57.210 -21.936 -7.301 1.00 13.89 ? 271 VAL A CB 1 ATOM 1932 C CG1 . VAL A 1 244 ? -56.373 -23.003 -7.979 1.00 15.81 ? 271 VAL A CG1 1 ATOM 1933 C CG2 . VAL A 1 244 ? -57.508 -22.336 -5.875 1.00 11.48 ? 271 VAL A CG2 1 ATOM 1934 N N . THR A 1 245 ? -54.853 -20.343 -5.582 1.00 14.46 ? 272 THR A N 1 ATOM 1935 C CA . THR A 1 245 ? -53.510 -20.325 -5.023 1.00 10.67 ? 272 THR A CA 1 ATOM 1936 C C . THR A 1 245 ? -53.362 -21.189 -3.769 1.00 11.56 ? 272 THR A C 1 ATOM 1937 O O . THR A 1 245 ? -52.261 -21.595 -3.425 1.00 14.95 ? 272 THR A O 1 ATOM 1938 C CB . THR A 1 245 ? -53.054 -18.894 -4.699 1.00 10.99 ? 272 THR A CB 1 ATOM 1939 O OG1 . THR A 1 245 ? -53.899 -18.339 -3.688 1.00 11.68 ? 272 THR A OG1 1 ATOM 1940 C CG2 . THR A 1 245 ? -53.116 -18.022 -5.934 1.00 11.63 ? 272 THR A CG2 1 ATOM 1941 N N . ASP A 1 246 ? -54.455 -21.468 -3.072 1.00 11.95 ? 273 ASP A N 1 ATOM 1942 C CA . ASP A 1 246 ? -54.369 -22.337 -1.900 1.00 11.23 ? 273 ASP A CA 1 ATOM 1943 C C . ASP A 1 246 ? -55.415 -23.446 -1.924 1.00 10.50 ? 273 ASP A C 1 ATOM 1944 O O . ASP A 1 246 ? -56.601 -23.202 -1.723 1.00 10.98 ? 273 ASP A O 1 ATOM 1945 C CB . ASP A 1 246 ? -54.508 -21.529 -0.611 1.00 12.44 ? 273 ASP A CB 1 ATOM 1946 C CG . ASP A 1 246 ? -53.959 -20.128 -0.746 1.00 21.58 ? 273 ASP A CG 1 ATOM 1947 O OD1 . ASP A 1 246 ? -52.766 -19.991 -1.100 1.00 18.60 ? 273 ASP A OD1 1 ATOM 1948 O OD2 . ASP A 1 246 ? -54.731 -19.166 -0.516 1.00 28.43 1 273 ASP A OD2 1 ATOM 1949 N N . ILE A 1 247 ? -54.968 -24.669 -2.174 1.00 7.91 ? 274 ILE A N 1 ATOM 1950 C CA . ILE A 1 247 ? -55.850 -25.816 -2.108 1.00 6.62 ? 274 ILE A CA 1 ATOM 1951 C C . ILE A 1 247 ? -55.567 -26.568 -0.816 1.00 7.51 ? 274 ILE A C 1 ATOM 1952 O O . ILE A 1 247 ? -54.507 -26.412 -0.220 1.00 8.97 ? 274 ILE A O 1 ATOM 1953 C CB . ILE A 1 247 ? -55.642 -26.728 -3.318 1.00 6.34 ? 274 ILE A CB 1 ATOM 1954 C CG1 . ILE A 1 247 ? -55.365 -25.873 -4.556 1.00 9.14 ? 274 ILE A CG1 1 ATOM 1955 C CG2 . ILE A 1 247 ? -56.845 -27.625 -3.525 1.00 6.79 ? 274 ILE A CG2 1 ATOM 1956 C CD1 . ILE A 1 247 ? -56.011 -26.376 -5.836 1.00 11.41 ? 274 ILE A CD1 1 ATOM 1957 N N . ASN A 1 248 ? -56.519 -27.372 -0.370 1.00 7.88 ? 275 ASN A N 1 ATOM 1958 C CA . ASN A 1 248 ? -56.334 -28.147 0.843 1.00 7.32 ? 275 ASN A CA 1 ATOM 1959 C C . ASN A 1 248 ? -57.178 -29.411 0.791 1.00 6.42 ? 275 ASN A C 1 ATOM 1960 O O . ASN A 1 248 ? -58.381 -29.378 1.028 1.00 6.74 ? 275 ASN A O 1 ATOM 1961 C CB . ASN A 1 248 ? -56.685 -27.302 2.064 1.00 7.50 ? 275 ASN A CB 1 ATOM 1962 C CG . ASN A 1 248 ? -56.261 -27.946 3.358 1.00 7.07 ? 275 ASN A CG 1 ATOM 1963 O OD1 . ASN A 1 248 ? -56.102 -29.163 3.433 1.00 6.72 ? 275 ASN A OD1 1 ATOM 1964 N ND2 . ASN A 1 248 ? -56.079 -27.133 4.392 1.00 7.61 ? 275 ASN A ND2 1 ATOM 1965 N N . LEU A 1 249 ? -56.533 -30.523 0.476 1.00 5.71 ? 276 LEU A N 1 ATOM 1966 C CA . LEU A 1 249 ? -57.228 -31.780 0.251 1.00 7.29 ? 276 LEU A CA 1 ATOM 1967 C C . LEU A 1 249 ? -56.992 -32.722 1.423 1.00 8.17 ? 276 LEU A C 1 ATOM 1968 O O . LEU A 1 249 ? -56.908 -33.939 1.254 1.00 8.85 ? 276 LEU A O 1 ATOM 1969 C CB . LEU A 1 249 ? -56.720 -32.415 -1.044 1.00 6.09 ? 276 LEU A CB 1 ATOM 1970 C CG . LEU A 1 249 ? -56.513 -31.396 -2.162 1.00 4.69 ? 276 LEU A CG 1 ATOM 1971 C CD1 . LEU A 1 249 ? -55.738 -31.977 -3.328 1.00 3.68 ? 276 LEU A CD1 1 ATOM 1972 C CD2 . LEU A 1 249 ? -57.861 -30.888 -2.613 1.00 7.88 ? 276 LEU A CD2 1 ATOM 1973 N N . SER A 1 250 ? -56.892 -32.154 2.617 1.00 7.48 ? 277 SER A N 1 ATOM 1974 C CA . SER A 1 250 ? -56.445 -32.923 3.771 1.00 7.96 ? 277 SER A CA 1 ATOM 1975 C C . SER A 1 250 ? -57.548 -33.725 4.457 1.00 9.75 ? 277 SER A C 1 ATOM 1976 O O . SER A 1 250 ? -58.736 -33.520 4.213 1.00 9.52 ? 277 SER A O 1 ATOM 1977 C CB . SER A 1 250 ? -55.769 -31.998 4.777 1.00 6.45 ? 277 SER A CB 1 ATOM 1978 O OG . SER A 1 250 ? -54.838 -31.165 4.118 1.00 6.68 ? 277 SER A OG 1 ATOM 1979 N N . ALA A 1 251 ? -57.129 -34.650 5.311 1.00 10.01 ? 278 ALA A N 1 ATOM 1980 C CA . ALA A 1 251 ? -58.039 -35.436 6.141 1.00 9.83 ? 278 ALA A CA 1 ATOM 1981 C C . ALA A 1 251 ? -59.029 -36.257 5.327 1.00 9.53 ? 278 ALA A C 1 ATOM 1982 O O . ALA A 1 251 ? -60.010 -36.759 5.866 1.00 10.71 ? 278 ALA A O 1 ATOM 1983 C CB . ALA A 1 251 ? -58.763 -34.548 7.159 1.00 7.52 ? 278 ALA A CB 1 ATOM 1984 N N . ASN A 1 252 ? -58.756 -36.409 4.034 1.00 9.57 ? 279 ASN A N 1 ATOM 1985 C CA . ASN A 1 252 ? -59.651 -37.145 3.151 1.00 12.42 ? 279 ASN A CA 1 ATOM 1986 C C . ASN A 1 252 ? -59.326 -38.636 3.092 1.00 14.26 ? 279 ASN A C 1 ATOM 1987 O O . ASN A 1 252 ? -58.838 -39.209 4.063 1.00 12.21 ? 279 ASN A O 1 ATOM 1988 C CB . ASN A 1 252 ? -59.664 -36.533 1.746 1.00 13.22 ? 279 ASN A CB 1 ATOM 1989 C CG . ASN A 1 252 ? -60.357 -35.174 1.699 1.00 11.53 ? 279 ASN A CG 1 ATOM 1990 O OD1 . ASN A 1 252 ? -61.401 -34.971 2.314 1.00 10.58 ? 279 ASN A OD1 1 ATOM 1991 N ND2 . ASN A 1 252 ? -59.771 -34.240 0.964 1.00 10.41 ? 279 ASN A ND2 1 ATOM 1992 N N . LEU A 1 253 ? -59.610 -39.263 1.955 1.00 21.41 ? 280 LEU A N 1 ATOM 1993 C CA . LEU A 1 253 ? -59.492 -40.717 1.828 1.00 22.03 ? 280 LEU A CA 1 ATOM 1994 C C . LEU A 1 253 ? -58.870 -41.165 0.507 1.00 19.56 ? 280 LEU A C 1 ATOM 1995 O O . LEU A 1 253 ? -59.150 -42.267 0.035 1.00 20.60 ? 280 LEU A O 1 ATOM 1996 C CB . LEU A 1 253 ? -60.867 -41.388 1.967 1.00 21.79 ? 280 LEU A CB 1 ATOM 1997 C CG . LEU A 1 253 ? -61.449 -41.731 3.341 1.00 19.43 ? 280 LEU A CG 1 ATOM 1998 C CD1 . LEU A 1 253 ? -61.944 -40.499 4.058 1.00 20.25 ? 280 LEU A CD1 1 ATOM 1999 C CD2 . LEU A 1 253 ? -62.577 -42.730 3.190 1.00 21.65 ? 280 LEU A CD2 1 ATOM 2000 N N . PHE A 1 254 ? -58.035 -40.320 -0.086 1.00 16.32 ? 281 PHE A N 1 ATOM 2001 C CA . PHE A 1 254 ? -57.419 -40.636 -1.370 1.00 18.05 ? 281 PHE A CA 1 ATOM 2002 C C . PHE A 1 254 ? -56.604 -41.922 -1.327 1.00 21.97 ? 281 PHE A C 1 ATOM 2003 O O . PHE A 1 254 ? -55.808 -42.130 -0.411 1.00 22.63 ? 281 PHE A O 1 ATOM 2004 C CB . PHE A 1 254 ? -56.512 -39.493 -1.820 1.00 19.96 ? 281 PHE A CB 1 ATOM 2005 C CG . PHE A 1 254 ? -57.238 -38.212 -2.102 1.00 20.28 ? 281 PHE A CG 1 ATOM 2006 C CD1 . PHE A 1 254 ? -57.467 -37.296 -1.093 1.00 17.50 ? 281 PHE A CD1 1 ATOM 2007 C CD2 . PHE A 1 254 ? -57.683 -37.919 -3.380 1.00 21.84 ? 281 PHE A CD2 1 ATOM 2008 C CE1 . PHE A 1 254 ? -58.128 -36.112 -1.352 1.00 16.30 ? 281 PHE A CE1 1 ATOM 2009 C CE2 . PHE A 1 254 ? -58.344 -36.739 -3.645 1.00 20.83 ? 281 PHE A CE2 1 ATOM 2010 C CZ . PHE A 1 254 ? -58.566 -35.835 -2.630 1.00 19.52 ? 281 PHE A CZ 1 ATOM 2011 N N . ARG A 1 255 ? -56.812 -42.785 -2.317 1.00 23.45 ? 282 ARG A N 1 ATOM 2012 C CA . ARG A 1 255 ? -55.937 -43.935 -2.531 1.00 26.13 ? 282 ARG A CA 1 ATOM 2013 C C . ARG A 1 255 ? -55.036 -43.624 -3.714 1.00 23.77 ? 282 ARG A C 1 ATOM 2014 O O . ARG A 1 255 ? -53.947 -44.188 -3.855 1.00 24.35 ? 282 ARG A O 1 ATOM 2015 C CB . ARG A 1 255 ? -56.741 -45.206 -2.809 1.00 24.20 ? 282 ARG A CB 1 ATOM 2016 C CG . ARG A 1 255 ? -57.326 -45.866 -1.574 1.00 29.84 ? 282 ARG A CG 1 ATOM 2017 C CD . ARG A 1 255 ? -56.566 -47.132 -1.201 1.00 32.54 ? 282 ARG A CD 1 ATOM 2018 N NE . ARG A 1 255 ? -57.323 -47.944 -0.254 1.00 42.32 ? 282 ARG A NE 1 ATOM 2019 C CZ . ARG A 1 255 ? -57.482 -47.635 1.029 1.00 49.86 ? 282 ARG A CZ 1 ATOM 2020 N NH1 . ARG A 1 255 ? -56.933 -46.531 1.517 1.00 38.56 1 282 ARG A NH1 1 ATOM 2021 N NH2 . ARG A 1 255 ? -58.189 -48.427 1.825 1.00 59.93 ? 282 ARG A NH2 1 ATOM 2022 N N . SER A 1 256 ? -55.507 -42.710 -4.555 1.00 17.11 ? 283 SER A N 1 ATOM 2023 C CA . SER A 1 256 ? -54.763 -42.272 -5.723 1.00 16.83 ? 283 SER A CA 1 ATOM 2024 C C . SER A 1 256 ? -55.266 -40.916 -6.188 1.00 18.67 ? 283 SER A C 1 ATOM 2025 O O . SER A 1 256 ? -56.303 -40.439 -5.736 1.00 21.50 ? 283 SER A O 1 ATOM 2026 C CB . SER A 1 256 ? -54.880 -43.297 -6.849 1.00 19.05 ? 283 SER A CB 1 ATOM 2027 O OG . SER A 1 256 ? -56.222 -43.704 -7.026 1.00 20.40 ? 283 SER A OG 1 ATOM 2028 N N . LEU A 1 257 ? -54.507 -40.287 -7.078 1.00 20.37 ? 284 LEU A N 1 ATOM 2029 C CA . LEU A 1 257 ? -54.879 -39.003 -7.650 1.00 18.68 ? 284 LEU A CA 1 ATOM 2030 C C . LEU A 1 257 ? -54.630 -39.055 -9.145 1.00 25.08 ? 284 LEU A C 1 ATOM 2031 O O . LEU A 1 257 ? -53.684 -39.699 -9.596 1.00 31.57 ? 284 LEU A O 1 ATOM 2032 C CB . LEU A 1 257 ? -54.053 -37.869 -7.043 1.00 14.99 ? 284 LEU A CB 1 ATOM 2033 C CG . LEU A 1 257 ? -54.548 -37.143 -5.795 1.00 9.88 ? 284 LEU A CG 1 ATOM 2034 C CD1 . LEU A 1 257 ? -54.525 -38.049 -4.593 1.00 12.33 ? 284 LEU A CD1 1 ATOM 2035 C CD2 . LEU A 1 257 ? -53.674 -35.940 -5.545 1.00 8.77 ? 284 LEU A CD2 1 ATOM 2036 N N . PRO A 1 258 ? -55.479 -38.378 -9.925 1.00 24.58 ? 285 PRO A N 1 ATOM 2037 C CA . PRO A 1 258 ? -55.294 -38.362 -11.375 1.00 22.15 ? 285 PRO A CA 1 ATOM 2038 C C . PRO A 1 258 ? -54.208 -37.377 -11.768 1.00 21.77 ? 285 PRO A C 1 ATOM 2039 O O . PRO A 1 258 ? -54.054 -36.337 -11.124 1.00 18.21 ? 285 PRO A O 1 ATOM 2040 C CB . PRO A 1 258 ? -56.647 -37.874 -11.881 1.00 32.99 ? 285 PRO A CB 1 ATOM 2041 C CG . PRO A 1 258 ? -57.148 -36.990 -10.785 1.00 28.03 ? 285 PRO A CG 1 ATOM 2042 C CD . PRO A 1 258 ? -56.674 -37.623 -9.507 1.00 26.59 ? 285 PRO A CD 1 ATOM 2043 N N . GLN A 1 259 ? -53.457 -37.706 -12.812 1.00 24.49 ? 286 GLN A N 1 ATOM 2044 C CA . GLN A 1 259 ? -52.431 -36.803 -13.305 1.00 23.75 ? 286 GLN A CA 1 ATOM 2045 C C . GLN A 1 259 ? -53.088 -35.578 -13.940 1.00 22.13 ? 286 GLN A C 1 ATOM 2046 O O . GLN A 1 259 ? -54.249 -35.626 -14.340 1.00 20.52 ? 286 GLN A O 1 ATOM 2047 C CB . GLN A 1 259 ? -51.513 -37.511 -14.302 1.00 21.76 ? 286 GLN A CB 1 ATOM 2048 C CG . GLN A 1 259 ? -50.183 -36.802 -14.501 1.00 25.41 ? 286 GLN A CG 1 ATOM 2049 C CD . GLN A 1 259 ? -49.351 -37.412 -15.605 1.00 21.89 ? 286 GLN A CD 1 ATOM 2050 O OE1 . GLN A 1 259 ? -49.617 -38.528 -16.054 1.00 17.60 ? 286 GLN A OE1 1 ATOM 2051 N NE2 . GLN A 1 259 ? -48.336 -36.677 -16.055 1.00 21.28 ? 286 GLN A NE2 1 ATOM 2052 N N . GLY A 1 260 ? -52.346 -34.478 -14.014 1.00 23.37 ? 287 GLY A N 1 ATOM 2053 C CA . GLY A 1 260 ? -52.876 -33.239 -14.545 1.00 21.47 ? 287 GLY A CA 1 ATOM 2054 C C . GLY A 1 260 ? -53.867 -32.579 -13.604 1.00 22.81 ? 287 GLY A C 1 ATOM 2055 O O . GLY A 1 260 ? -54.547 -31.628 -13.990 1.00 27.57 ? 287 GLY A O 1 ATOM 2056 N N . LEU A 1 261 ? -53.944 -33.079 -12.372 1.00 18.37 ? 288 LEU A N 1 ATOM 2057 C CA . LEU A 1 261 ? -54.894 -32.579 -11.377 1.00 16.42 ? 288 LEU A CA 1 ATOM 2058 C C . LEU A 1 261 ? -54.813 -31.066 -11.168 1.00 17.37 ? 288 LEU A C 1 ATOM 2059 O O . LEU A 1 261 ? -55.836 -30.412 -10.942 1.00 15.92 ? 288 LEU A O 1 ATOM 2060 C CB . LEU A 1 261 ? -54.701 -33.304 -10.043 1.00 16.10 ? 288 LEU A CB 1 ATOM 2061 C CG . LEU A 1 261 ? -55.552 -32.821 -8.864 1.00 14.95 ? 288 LEU A CG 1 ATOM 2062 C CD1 . LEU A 1 261 ? -57.016 -33.167 -9.055 1.00 19.33 ? 288 LEU A CD1 1 ATOM 2063 C CD2 . LEU A 1 261 ? -55.040 -33.403 -7.565 1.00 13.42 ? 288 LEU A CD2 1 ATOM 2064 N N . PHE A 1 262 ? -53.603 -30.514 -11.253 1.00 17.29 ? 289 PHE A N 1 ATOM 2065 C CA . PHE A 1 262 ? -53.403 -29.074 -11.103 1.00 14.67 ? 289 PHE A CA 1 ATOM 2066 C C . PHE A 1 262 ? -52.912 -28.407 -12.381 1.00 19.16 ? 289 PHE A C 1 ATOM 2067 O O . PHE A 1 262 ? -52.499 -27.245 -12.356 1.00 16.16 ? 289 PHE A O 1 ATOM 2068 C CB . PHE A 1 262 ? -52.424 -28.777 -9.975 1.00 12.83 ? 289 PHE A CB 1 ATOM 2069 C CG . PHE A 1 262 ? -52.860 -29.299 -8.644 1.00 13.83 ? 289 PHE A CG 1 ATOM 2070 C CD1 . PHE A 1 262 ? -53.834 -28.648 -7.916 1.00 12.76 ? 289 PHE A CD1 1 ATOM 2071 C CD2 . PHE A 1 262 ? -52.287 -30.441 -8.114 1.00 14.50 ? 289 PHE A CD2 1 ATOM 2072 C CE1 . PHE A 1 262 ? -54.232 -29.132 -6.690 1.00 14.00 ? 289 PHE A CE1 1 ATOM 2073 C CE2 . PHE A 1 262 ? -52.681 -30.926 -6.885 1.00 11.36 ? 289 PHE A CE2 1 ATOM 2074 C CZ . PHE A 1 262 ? -53.652 -30.274 -6.173 1.00 12.89 ? 289 PHE A CZ 1 ATOM 2075 N N . ASP A 1 263 ? -52.970 -29.146 -13.488 1.00 23.75 ? 290 ASP A N 1 ATOM 2076 C CA . ASP A 1 263 ? -52.493 -28.679 -14.792 1.00 24.38 ? 290 ASP A CA 1 ATOM 2077 C C . ASP A 1 263 ? -53.031 -27.315 -15.226 1.00 27.79 ? 290 ASP A C 1 ATOM 2078 O O . ASP A 1 263 ? -52.315 -26.533 -15.850 1.00 25.11 ? 290 ASP A O 1 ATOM 2079 C CB . ASP A 1 263 ? -52.817 -29.710 -15.874 1.00 24.76 ? 290 ASP A CB 1 ATOM 2080 C CG . ASP A 1 263 ? -51.613 -30.530 -16.273 1.00 32.54 ? 290 ASP A CG 1 ATOM 2081 O OD1 . ASP A 1 263 ? -50.811 -30.876 -15.382 1.00 40.59 ? 290 ASP A OD1 1 ATOM 2082 O OD2 . ASP A 1 263 ? -51.460 -30.823 -17.478 1.00 36.27 1 290 ASP A OD2 1 ATOM 2083 N N . HIS A 1 264 ? -54.291 -27.038 -14.903 1.00 28.50 ? 291 HIS A N 1 ATOM 2084 C CA . HIS A 1 264 ? -54.938 -25.802 -15.337 1.00 26.52 ? 291 HIS A CA 1 ATOM 2085 C C . HIS A 1 264 ? -54.777 -24.658 -14.329 1.00 23.84 ? 291 HIS A C 1 ATOM 2086 O O . HIS A 1 264 ? -55.174 -23.520 -14.589 1.00 19.17 ? 291 HIS A O 1 ATOM 2087 C CB . HIS A 1 264 ? -56.415 -26.067 -15.630 1.00 25.07 ? 291 HIS A CB 1 ATOM 2088 C CG . HIS A 1 264 ? -56.642 -27.217 -16.560 1.00 32.49 ? 291 HIS A CG 1 ATOM 2089 N ND1 . HIS A 1 264 ? -57.077 -28.451 -16.125 1.00 37.45 ? 291 HIS A ND1 1 ATOM 2090 C CD2 . HIS A 1 264 ? -56.469 -27.330 -17.899 1.00 36.68 ? 291 HIS A CD2 1 ATOM 2091 C CE1 . HIS A 1 264 ? -57.178 -29.269 -17.158 1.00 38.78 ? 291 HIS A CE1 1 ATOM 2092 N NE2 . HIS A 1 264 ? -56.814 -28.614 -18.246 1.00 38.84 ? 291 HIS A NE2 1 ATOM 2093 N N . ASN A 1 265 ? -54.175 -24.967 -13.186 1.00 22.34 ? 292 ASN A N 1 ATOM 2094 C CA . ASN A 1 265 ? -53.979 -23.980 -12.133 1.00 22.12 ? 292 ASN A CA 1 ATOM 2095 C C . ASN A 1 265 ? -52.500 -23.684 -11.905 1.00 22.50 ? 292 ASN A C 1 ATOM 2096 O O . ASN A 1 265 ? -51.913 -24.091 -10.904 1.00 18.72 ? 292 ASN A O 1 ATOM 2097 C CB . ASN A 1 265 ? -54.617 -24.479 -10.847 1.00 18.45 ? 292 ASN A CB 1 ATOM 2098 C CG . ASN A 1 265 ? -55.640 -25.556 -11.102 1.00 17.68 ? 292 ASN A CG 1 ATOM 2099 O OD1 . ASN A 1 265 ? -55.437 -26.713 -10.748 1.00 17.57 ? 292 ASN A OD1 1 ATOM 2100 N ND2 . ASN A 1 265 ? -56.743 -25.185 -11.732 1.00 19.44 ? 292 ASN A ND2 1 ATOM 2101 N N . LYS A 1 266 ? -51.901 -22.968 -12.846 1.00 20.82 ? 293 LYS A N 1 ATOM 2102 C CA . LYS A 1 266 ? -50.497 -22.623 -12.755 1.00 17.37 ? 293 LYS A CA 1 ATOM 2103 C C . LYS A 1 266 ? -50.295 -21.308 -12.006 1.00 20.36 ? 293 LYS A C 1 ATOM 2104 O O . LYS A 1 266 ? -49.386 -20.539 -12.318 1.00 26.05 ? 293 LYS A O 1 ATOM 2105 C CB . LYS A 1 266 ? -49.879 -22.557 -14.151 1.00 19.65 ? 293 LYS A CB 1 ATOM 2106 C CG . LYS A 1 266 ? -49.922 -23.878 -14.906 1.00 21.11 ? 293 LYS A CG 1 ATOM 2107 C CD . LYS A 1 266 ? -49.289 -25.004 -14.097 1.00 19.16 ? 293 LYS A CD 1 ATOM 2108 C CE . LYS A 1 266 ? -49.251 -26.306 -14.881 1.00 21.63 ? 293 LYS A CE 1 ATOM 2109 N NZ . LYS A 1 266 ? -48.592 -26.125 -16.207 1.00 23.55 1 293 LYS A NZ 1 ATOM 2110 N N . HIS A 1 267 ? -51.147 -21.051 -11.020 1.00 16.64 ? 294 HIS A N 1 ATOM 2111 C CA . HIS A 1 267 ? -50.967 -19.906 -10.137 1.00 16.29 ? 294 HIS A CA 1 ATOM 2112 C C . HIS A 1 267 ? -50.864 -20.366 -8.691 1.00 18.09 ? 294 HIS A C 1 ATOM 2113 O O . HIS A 1 267 ? -50.850 -19.544 -7.772 1.00 17.48 ? 294 HIS A O 1 ATOM 2114 C CB . HIS A 1 267 ? -52.115 -18.912 -10.287 1.00 19.92 ? 294 HIS A CB 1 ATOM 2115 C CG . HIS A 1 267 ? -51.858 -17.841 -11.298 1.00 20.25 ? 294 HIS A CG 1 ATOM 2116 N ND1 . HIS A 1 267 ? -51.889 -18.076 -12.656 1.00 20.94 ? 294 HIS A ND1 1 ATOM 2117 C CD2 . HIS A 1 267 ? -51.564 -16.528 -11.149 1.00 20.66 ? 294 HIS A CD2 1 ATOM 2118 C CE1 . HIS A 1 267 ? -51.624 -16.953 -13.300 1.00 24.70 ? 294 HIS A CE1 1 ATOM 2119 N NE2 . HIS A 1 267 ? -51.422 -15.999 -12.408 1.00 25.77 ? 294 HIS A NE2 1 ATOM 2120 N N . LEU A 1 268 ? -50.793 -21.686 -8.507 1.00 20.13 ? 295 LEU A N 1 ATOM 2121 C CA . LEU A 1 268 ? -50.693 -22.310 -7.186 1.00 12.76 ? 295 LEU A CA 1 ATOM 2122 C C . LEU A 1 268 ? -49.569 -21.725 -6.351 1.00 12.10 ? 295 LEU A C 1 ATOM 2123 O O . LEU A 1 268 ? -48.497 -21.424 -6.858 1.00 15.13 ? 295 LEU A O 1 ATOM 2124 C CB . LEU A 1 268 ? -50.484 -23.819 -7.312 1.00 11.43 ? 295 LEU A CB 1 ATOM 2125 C CG . LEU A 1 268 ? -51.715 -24.653 -7.653 1.00 12.74 ? 295 LEU A CG 1 ATOM 2126 C CD1 . LEU A 1 268 ? -51.361 -26.128 -7.713 1.00 9.58 ? 295 LEU A CD1 1 ATOM 2127 C CD2 . LEU A 1 268 ? -52.814 -24.395 -6.637 1.00 11.85 ? 295 LEU A CD2 1 ATOM 2128 N N . ASN A 1 269 ? -49.829 -21.576 -5.062 1.00 12.67 ? 296 ASN A N 1 ATOM 2129 C CA . ASN A 1 269 ? -48.886 -20.965 -4.146 1.00 11.18 ? 296 ASN A CA 1 ATOM 2130 C C . ASN A 1 269 ? -48.635 -21.888 -2.967 1.00 11.46 ? 296 ASN A C 1 ATOM 2131 O O . ASN A 1 269 ? -47.641 -21.745 -2.259 1.00 14.24 ? 296 ASN A O 1 ATOM 2132 C CB . ASN A 1 269 ? -49.450 -19.642 -3.638 1.00 12.63 ? 296 ASN A CB 1 ATOM 2133 C CG . ASN A 1 269 ? -48.439 -18.525 -3.677 1.00 18.58 ? 296 ASN A CG 1 ATOM 2134 O OD1 . ASN A 1 269 ? -47.498 -18.495 -2.879 1.00 16.92 ? 296 ASN A OD1 1 ATOM 2135 N ND2 . ASN A 1 269 ? -48.634 -17.583 -4.601 1.00 20.71 ? 296 ASN A ND2 1 ATOM 2136 N N . GLU A 1 270 ? -49.549 -22.831 -2.762 1.00 8.60 ? 297 GLU A N 1 ATOM 2137 C CA . GLU A 1 270 ? -49.479 -23.748 -1.638 1.00 7.81 ? 297 GLU A CA 1 ATOM 2138 C C . GLU A 1 270 ? -50.586 -24.783 -1.728 1.00 8.01 ? 297 GLU A C 1 ATOM 2139 O O . GLU A 1 270 ? -51.762 -24.455 -1.637 1.00 9.53 ? 297 GLU A O 1 ATOM 2140 C CB . GLU A 1 270 ? -49.590 -22.987 -0.313 1.00 8.91 ? 297 GLU A CB 1 ATOM 2141 C CG . GLU A 1 270 ? -49.523 -23.857 0.934 1.00 9.75 ? 297 GLU A CG 1 ATOM 2142 C CD . GLU A 1 270 ? -49.682 -23.043 2.213 1.00 14.98 ? 297 GLU A CD 1 ATOM 2143 O OE1 . GLU A 1 270 ? -49.734 -23.648 3.313 1.00 10.80 ? 297 GLU A OE1 1 ATOM 2144 O OE2 . GLU A 1 270 ? -49.756 -21.793 2.112 1.00 12.67 1 297 GLU A OE2 1 ATOM 2145 N N . VAL A 1 271 ? -50.200 -26.034 -1.923 1.00 7.63 ? 298 VAL A N 1 ATOM 2146 C CA . VAL A 1 271 ? -51.122 -27.151 -1.832 1.00 6.28 ? 298 VAL A CA 1 ATOM 2147 C C . VAL A 1 271 ? -50.807 -27.887 -0.540 1.00 7.21 ? 298 VAL A C 1 ATOM 2148 O O . VAL A 1 271 ? -49.651 -27.948 -0.124 1.00 6.95 ? 298 VAL A O 1 ATOM 2149 C CB . VAL A 1 271 ? -50.932 -28.106 -3.009 1.00 5.48 ? 298 VAL A CB 1 ATOM 2150 C CG1 . VAL A 1 271 ? -51.974 -29.206 -2.979 1.00 5.42 ? 298 VAL A CG1 1 ATOM 2151 C CG2 . VAL A 1 271 ? -51.000 -27.342 -4.305 1.00 7.19 ? 298 VAL A CG2 1 ATOM 2152 N N . ARG A 1 272 ? -51.830 -28.422 0.116 1.00 7.48 ? 299 ARG A N 1 ATOM 2153 C CA . ARG A 1 272 ? -51.621 -29.219 1.321 1.00 7.25 ? 299 ARG A CA 1 ATOM 2154 C C . ARG A 1 272 ? -52.476 -30.484 1.276 1.00 7.20 ? 299 ARG A C 1 ATOM 2155 O O . ARG A 1 272 ? -53.692 -30.415 1.106 1.00 7.99 ? 299 ARG A O 1 ATOM 2156 C CB . ARG A 1 272 ? -51.916 -28.397 2.583 1.00 5.79 ? 299 ARG A CB 1 ATOM 2157 C CG . ARG A 1 272 ? -51.314 -26.997 2.551 1.00 6.82 ? 299 ARG A CG 1 ATOM 2158 C CD . ARG A 1 272 ? -51.224 -26.370 3.924 1.00 8.48 ? 299 ARG A CD 1 ATOM 2159 N NE . ARG A 1 272 ? -52.513 -26.345 4.604 1.00 16.39 ? 299 ARG A NE 1 ATOM 2160 C CZ . ARG A 1 272 ? -52.911 -25.370 5.418 1.00 19.76 ? 299 ARG A CZ 1 ATOM 2161 N NH1 . ARG A 1 272 ? -52.117 -24.327 5.646 1.00 18.28 1 299 ARG A NH1 1 ATOM 2162 N NH2 . ARG A 1 272 ? -54.107 -25.437 5.997 1.00 14.34 ? 299 ARG A NH2 1 ATOM 2163 N N . LEU A 1 273 ? -51.828 -31.637 1.407 1.00 6.58 ? 300 LEU A N 1 ATOM 2164 C CA . LEU A 1 273 ? -52.523 -32.917 1.442 1.00 5.93 ? 300 LEU A CA 1 ATOM 2165 C C . LEU A 1 273 ? -52.128 -33.642 2.723 1.00 5.18 ? 300 LEU A C 1 ATOM 2166 O O . LEU A 1 273 ? -51.597 -34.746 2.698 1.00 6.17 ? 300 LEU A O 1 ATOM 2167 C CB . LEU A 1 273 ? -52.160 -33.754 0.213 1.00 5.33 ? 300 LEU A CB 1 ATOM 2168 C CG . LEU A 1 273 ? -53.212 -34.675 -0.416 1.00 4.05 ? 300 LEU A CG 1 ATOM 2169 C CD1 . LEU A 1 273 ? -52.657 -35.335 -1.667 1.00 3.55 ? 300 LEU A CD1 1 ATOM 2170 C CD2 . LEU A 1 273 ? -53.693 -35.731 0.557 1.00 5.94 ? 300 LEU A CD2 1 ATOM 2171 N N . MET A 1 274 ? -52.388 -33.009 3.852 1.00 4.07 ? 301 MET A N 1 ATOM 2172 C CA . MET A 1 274 ? -51.953 -33.557 5.117 1.00 5.24 ? 301 MET A CA 1 ATOM 2173 C C . MET A 1 274 ? -52.914 -34.592 5.678 1.00 7.69 ? 301 MET A C 1 ATOM 2174 O O . MET A 1 274 ? -54.114 -34.534 5.435 1.00 8.75 ? 301 MET A O 1 ATOM 2175 C CB . MET A 1 274 ? -51.791 -32.432 6.128 1.00 5.70 ? 301 MET A CB 1 ATOM 2176 C CG . MET A 1 274 ? -50.677 -31.471 5.818 1.00 4.57 ? 301 MET A CG 1 ATOM 2177 S SD . MET A 1 274 ? -50.869 -30.028 6.864 1.00 2.47 ? 301 MET A SD 1 ATOM 2178 C CE . MET A 1 274 ? -52.310 -29.290 6.132 1.00 9.62 ? 301 MET A CE 1 ATOM 2179 N N . ASN A 1 275 ? -52.365 -35.545 6.425 1.00 9.07 ? 302 ASN A N 1 ATOM 2180 C CA . ASN A 1 275 ? -53.152 -36.437 7.275 1.00 9.62 ? 302 ASN A CA 1 ATOM 2181 C C . ASN A 1 275 ? -54.277 -37.238 6.616 1.00 9.67 ? 302 ASN A C 1 ATOM 2182 O O . ASN A 1 275 ? -55.350 -37.411 7.191 1.00 7.89 ? 302 ASN A O 1 ATOM 2183 C CB . ASN A 1 275 ? -53.683 -35.664 8.477 1.00 8.24 ? 302 ASN A CB 1 ATOM 2184 C CG . ASN A 1 275 ? -52.802 -35.817 9.676 1.00 11.26 ? 302 ASN A CG 1 ATOM 2185 O OD1 . ASN A 1 275 ? -52.496 -36.936 10.090 1.00 10.21 ? 302 ASN A OD1 1 ATOM 2186 N ND2 . ASN A 1 275 ? -52.357 -34.699 10.231 1.00 16.75 ? 302 ASN A ND2 1 ATOM 2187 N N . ASN A 1 276 ? -54.016 -37.740 5.420 1.00 8.81 ? 303 ASN A N 1 ATOM 2188 C CA . ASN A 1 276 ? -54.975 -38.580 4.726 1.00 9.60 ? 303 ASN A CA 1 ATOM 2189 C C . ASN A 1 276 ? -55.404 -39.783 5.557 1.00 11.01 ? 303 ASN A C 1 ATOM 2190 O O . ASN A 1 276 ? -54.594 -40.638 5.886 1.00 16.29 ? 303 ASN A O 1 ATOM 2191 C CB . ASN A 1 276 ? -54.383 -39.053 3.411 1.00 10.67 ? 303 ASN A CB 1 ATOM 2192 C CG . ASN A 1 276 ? -55.384 -39.033 2.297 1.00 17.33 ? 303 ASN A CG 1 ATOM 2193 O OD1 . ASN A 1 276 ? -55.589 -40.037 1.615 1.00 21.11 ? 303 ASN A OD1 1 ATOM 2194 N ND2 . ASN A 1 276 ? -56.037 -37.885 2.109 1.00 15.52 ? 303 ASN A ND2 1 ATOM 2195 N N . ARG A 1 277 ? -56.688 -39.852 5.877 1.00 13.56 ? 304 ARG A N 1 ATOM 2196 C CA . ARG A 1 277 ? -57.210 -40.889 6.763 1.00 13.06 ? 304 ARG A CA 1 ATOM 2197 C C . ARG A 1 277 ? -57.038 -42.323 6.239 1.00 14.01 ? 304 ARG A C 1 ATOM 2198 O O . ARG A 1 277 ? -57.325 -43.277 6.956 1.00 15.57 ? 304 ARG A O 1 ATOM 2199 C CB . ARG A 1 277 ? -58.673 -40.606 7.135 1.00 11.17 ? 304 ARG A CB 1 ATOM 2200 C CG . ARG A 1 277 ? -58.862 -39.695 8.359 1.00 12.96 ? 304 ARG A CG 1 ATOM 2201 C CD . ARG A 1 277 ? -58.199 -38.334 8.167 1.00 14.48 ? 304 ARG A CD 1 ATOM 2202 N NE . ARG A 1 277 ? -58.383 -37.416 9.293 1.00 17.53 ? 304 ARG A NE 1 ATOM 2203 C CZ . ARG A 1 277 ? -57.490 -37.221 10.261 1.00 15.66 ? 304 ARG A CZ 1 ATOM 2204 N NH1 . ARG A 1 277 ? -56.343 -37.885 10.258 1.00 16.09 1 304 ARG A NH1 1 ATOM 2205 N NH2 . ARG A 1 277 ? -57.744 -36.362 11.237 1.00 16.03 ? 304 ARG A NH2 1 ATOM 2206 N N . VAL A 1 278 ? -56.581 -42.475 4.998 1.00 15.74 ? 305 VAL A N 1 ATOM 2207 C CA . VAL A 1 278 ? -56.148 -43.786 4.495 1.00 22.72 ? 305 VAL A CA 1 ATOM 2208 C C . VAL A 1 278 ? -54.852 -43.674 3.676 1.00 22.53 ? 305 VAL A C 1 ATOM 2209 O O . VAL A 1 278 ? -54.615 -42.650 3.026 1.00 20.00 ? 305 VAL A O 1 ATOM 2210 C CB . VAL A 1 278 ? -57.241 -44.523 3.652 1.00 23.03 ? 305 VAL A CB 1 ATOM 2211 C CG1 . VAL A 1 278 ? -58.428 -44.932 4.510 1.00 19.82 ? 305 VAL A CG1 1 ATOM 2212 C CG2 . VAL A 1 278 ? -57.669 -43.692 2.464 1.00 24.94 ? 305 VAL A CG2 1 ATOM 2213 N N . PRO A 1 279 ? -54.009 -44.726 3.715 1.00 18.82 ? 306 PRO A N 1 ATOM 2214 C CA . PRO A 1 279 ? -52.717 -44.827 3.024 1.00 17.52 ? 306 PRO A CA 1 ATOM 2215 C C . PRO A 1 279 ? -52.731 -44.526 1.526 1.00 20.47 ? 306 PRO A C 1 ATOM 2216 O O . PRO A 1 279 ? -53.296 -45.300 0.749 1.00 23.27 ? 306 PRO A O 1 ATOM 2217 C CB . PRO A 1 279 ? -52.332 -46.297 3.233 1.00 20.07 ? 306 PRO A CB 1 ATOM 2218 C CG . PRO A 1 279 ? -53.579 -46.973 3.720 1.00 18.00 ? 306 PRO A CG 1 ATOM 2219 C CD . PRO A 1 279 ? -54.253 -45.929 4.524 1.00 18.09 ? 306 PRO A CD 1 ATOM 2220 N N . LEU A 1 280 ? -52.081 -43.429 1.140 1.00 17.33 ? 307 LEU A N 1 ATOM 2221 C CA . LEU A 1 280 ? -51.912 -43.054 -0.263 1.00 18.28 ? 307 LEU A CA 1 ATOM 2222 C C . LEU A 1 280 ? -50.481 -43.339 -0.737 1.00 23.43 ? 307 LEU A C 1 ATOM 2223 O O . LEU A 1 280 ? -49.546 -42.596 -0.421 1.00 23.54 ? 307 LEU A O 1 ATOM 2224 C CB . LEU A 1 280 ? -52.261 -41.578 -0.458 1.00 18.25 ? 307 LEU A CB 1 ATOM 2225 C CG . LEU A 1 280 ? -51.779 -40.878 -1.732 1.00 21.09 ? 307 LEU A CG 1 ATOM 2226 C CD1 . LEU A 1 280 ? -52.352 -41.527 -2.976 1.00 20.73 ? 307 LEU A CD1 1 ATOM 2227 C CD2 . LEU A 1 280 ? -52.124 -39.399 -1.690 1.00 20.86 ? 307 LEU A CD2 1 ATOM 2228 N N . ALA A 1 281 ? -50.334 -44.414 -1.510 1.00 26.23 ? 308 ALA A N 1 ATOM 2229 C CA . ALA A 1 281 ? -49.033 -44.968 -1.902 1.00 19.66 ? 308 ALA A CA 1 ATOM 2230 C C . ALA A 1 281 ? -48.046 -43.974 -2.503 1.00 20.08 ? 308 ALA A C 1 ATOM 2231 O O . ALA A 1 281 ? -46.891 -43.919 -2.091 1.00 21.53 ? 308 ALA A O 1 ATOM 2232 C CB . ALA A 1 281 ? -49.234 -46.128 -2.858 1.00 22.68 ? 308 ALA A CB 1 ATOM 2233 N N . THR A 1 282 ? -48.499 -43.207 -3.489 1.00 22.77 ? 309 THR A N 1 ATOM 2234 C CA . THR A 1 282 ? -47.627 -42.267 -4.189 1.00 26.85 ? 309 THR A CA 1 ATOM 2235 C C . THR A 1 282 ? -48.405 -41.187 -4.938 1.00 28.71 ? 309 THR A C 1 ATOM 2236 O O . THR A 1 282 ? -49.596 -41.336 -5.207 1.00 35.16 ? 309 THR A O 1 ATOM 2237 C CB . THR A 1 282 ? -46.704 -42.999 -5.186 1.00 26.51 ? 309 THR A CB 1 ATOM 2238 O OG1 . THR A 1 282 ? -46.219 -42.071 -6.166 1.00 24.37 ? 309 THR A OG1 1 ATOM 2239 C CG2 . THR A 1 282 ? -47.460 -44.114 -5.884 1.00 26.70 ? 309 THR A CG2 1 ATOM 2240 N N . LEU A 1 283 ? -47.721 -40.097 -5.268 1.00 28.80 ? 310 LEU A N 1 ATOM 2241 C CA . LEU A 1 283 ? -48.314 -39.030 -6.062 1.00 28.36 ? 310 LEU A CA 1 ATOM 2242 C C . LEU A 1 283 ? -48.004 -39.270 -7.533 1.00 34.76 ? 310 LEU A C 1 ATOM 2243 O O . LEU A 1 283 ? -46.878 -39.628 -7.875 1.00 39.05 ? 310 LEU A O 1 ATOM 2244 C CB . LEU A 1 283 ? -47.758 -37.672 -5.635 1.00 26.80 ? 310 LEU A CB 1 ATOM 2245 C CG . LEU A 1 283 ? -47.822 -37.349 -4.141 1.00 27.82 ? 310 LEU A CG 1 ATOM 2246 C CD1 . LEU A 1 283 ? -47.349 -35.923 -3.864 1.00 18.65 ? 310 LEU A CD1 1 ATOM 2247 C CD2 . LEU A 1 283 ? -49.224 -37.583 -3.592 1.00 24.33 ? 310 LEU A CD2 1 ATOM 2248 N N . PRO A 1 284 ? -49.008 -39.092 -8.408 1.00 40.80 ? 311 PRO A N 1 ATOM 2249 C CA . PRO A 1 284 ? -48.836 -39.240 -9.861 1.00 36.64 ? 311 PRO A CA 1 ATOM 2250 C C . PRO A 1 284 ? -47.751 -38.338 -10.449 1.00 28.51 ? 311 PRO A C 1 ATOM 2251 O O . PRO A 1 284 ? -47.430 -37.297 -9.873 1.00 27.05 ? 311 PRO A O 1 ATOM 2252 C CB . PRO A 1 284 ? -50.214 -38.850 -10.424 1.00 37.62 ? 311 PRO A CB 1 ATOM 2253 C CG . PRO A 1 284 ? -50.961 -38.216 -9.278 1.00 28.94 ? 311 PRO A CG 1 ATOM 2254 C CD . PRO A 1 284 ? -50.418 -38.868 -8.050 1.00 33.43 ? 311 PRO A CD 1 ATOM 2255 N N . SER A 1 285 ? -47.204 -38.753 -11.589 1.00 25.51 ? 312 SER A N 1 ATOM 2256 C CA . SER A 1 285 ? -46.149 -38.018 -12.280 1.00 28.03 ? 312 SER A CA 1 ATOM 2257 C C . SER A 1 285 ? -46.428 -36.523 -12.398 1.00 31.08 ? 312 SER A C 1 ATOM 2258 O O . SER A 1 285 ? -47.584 -36.106 -12.524 1.00 30.37 ? 312 SER A O 1 ATOM 2259 C CB . SER A 1 285 ? -45.930 -38.607 -13.678 1.00 25.94 ? 312 SER A CB 1 ATOM 2260 O OG . SER A 1 285 ? -45.255 -37.690 -14.525 1.00 23.13 ? 312 SER A OG 1 ATOM 2261 N N . ARG A 1 286 ? -45.359 -35.729 -12.334 1.00 29.87 ? 313 ARG A N 1 ATOM 2262 C CA . ARG A 1 286 ? -45.415 -34.285 -12.575 1.00 29.35 ? 313 ARG A CA 1 ATOM 2263 C C . ARG A 1 286 ? -46.561 -33.552 -11.876 1.00 33.14 ? 313 ARG A C 1 ATOM 2264 O O . ARG A 1 286 ? -47.026 -32.518 -12.368 1.00 33.32 ? 313 ARG A O 1 ATOM 2265 C CB . ARG A 1 286 ? -45.504 -34.003 -14.073 1.00 31.45 ? 313 ARG A CB 1 ATOM 2266 C CG . ARG A 1 286 ? -44.225 -34.198 -14.840 1.00 31.01 ? 313 ARG A CG 1 ATOM 2267 C CD . ARG A 1 286 ? -44.437 -33.769 -16.279 1.00 44.95 ? 313 ARG A CD 1 ATOM 2268 N NE . ARG A 1 286 ? -43.716 -34.627 -17.211 1.00 56.36 ? 313 ARG A NE 1 ATOM 2269 C CZ . ARG A 1 286 ? -42.610 -34.270 -17.853 1.00 49.35 ? 313 ARG A CZ 1 ATOM 2270 N NH1 . ARG A 1 286 ? -42.096 -33.057 -17.675 1.00 41.82 1 313 ARG A NH1 1 ATOM 2271 N NH2 . ARG A 1 286 ? -42.025 -35.127 -18.678 1.00 37.88 ? 313 ARG A NH2 1 ATOM 2272 N N . LEU A 1 287 ? -47.015 -34.091 -10.747 1.00 28.86 ? 314 LEU A N 1 ATOM 2273 C CA . LEU A 1 287 ? -48.175 -33.551 -10.048 1.00 23.52 ? 314 LEU A CA 1 ATOM 2274 C C . LEU A 1 287 ? -47.982 -32.076 -9.714 1.00 21.49 ? 314 LEU A C 1 ATOM 2275 O O . LEU A 1 287 ? -48.901 -31.274 -9.878 1.00 21.46 ? 314 LEU A O 1 ATOM 2276 C CB . LEU A 1 287 ? -48.471 -34.363 -8.784 1.00 22.86 ? 314 LEU A CB 1 ATOM 2277 C CG . LEU A 1 287 ? -49.875 -34.273 -8.173 1.00 19.68 ? 314 LEU A CG 1 ATOM 2278 C CD1 . LEU A 1 287 ? -50.104 -35.425 -7.231 1.00 22.25 ? 314 LEU A CD1 1 ATOM 2279 C CD2 . LEU A 1 287 ? -50.072 -32.986 -7.419 1.00 17.12 ? 314 LEU A CD2 1 ATOM 2280 N N . PHE A 1 288 ? -46.789 -31.717 -9.253 1.00 18.41 ? 315 PHE A N 1 ATOM 2281 C CA . PHE A 1 288 ? -46.504 -30.319 -8.954 1.00 20.34 ? 315 PHE A CA 1 ATOM 2282 C C . PHE A 1 288 ? -45.528 -29.704 -9.962 1.00 21.46 ? 315 PHE A C 1 ATOM 2283 O O . PHE A 1 288 ? -44.986 -28.618 -9.743 1.00 18.73 ? 315 PHE A O 1 ATOM 2284 C CB . PHE A 1 288 ? -45.999 -30.160 -7.518 1.00 15.16 ? 315 PHE A CB 1 ATOM 2285 C CG . PHE A 1 288 ? -46.967 -30.652 -6.477 1.00 18.31 ? 315 PHE A CG 1 ATOM 2286 C CD1 . PHE A 1 288 ? -48.119 -29.939 -6.189 1.00 16.17 ? 315 PHE A CD1 1 ATOM 2287 C CD2 . PHE A 1 288 ? -46.726 -31.829 -5.783 1.00 21.86 ? 315 PHE A CD2 1 ATOM 2288 C CE1 . PHE A 1 288 ? -49.015 -30.395 -5.230 1.00 15.24 ? 315 PHE A CE1 1 ATOM 2289 C CE2 . PHE A 1 288 ? -47.619 -32.289 -4.820 1.00 16.04 ? 315 PHE A CE2 1 ATOM 2290 C CZ . PHE A 1 288 ? -48.760 -31.571 -4.543 1.00 11.28 ? 315 PHE A CZ 1 ATOM 2291 N N . ALA A 1 289 ? -45.331 -30.391 -11.083 1.00 19.76 ? 316 ALA A N 1 ATOM 2292 C CA . ALA A 1 289 ? -44.380 -29.935 -12.087 1.00 19.14 ? 316 ALA A CA 1 ATOM 2293 C C . ALA A 1 289 ? -44.915 -28.790 -12.928 1.00 19.86 ? 316 ALA A C 1 ATOM 2294 O O . ALA A 1 289 ? -46.118 -28.700 -13.180 1.00 26.18 ? 316 ALA A O 1 ATOM 2295 C CB . ALA A 1 289 ? -43.966 -31.080 -12.982 1.00 25.29 ? 316 ALA A CB 1 ATOM 2296 N N . ASN A 1 290 ? -43.996 -27.934 -13.367 1.00 17.19 ? 317 ASN A N 1 ATOM 2297 C CA . ASN A 1 290 ? -44.293 -26.805 -14.247 1.00 16.93 ? 317 ASN A CA 1 ATOM 2298 C C . ASN A 1 290 ? -45.160 -25.749 -13.584 1.00 16.43 ? 317 ASN A C 1 ATOM 2299 O O . ASN A 1 290 ? -45.982 -25.117 -14.237 1.00 18.96 ? 317 ASN A O 1 ATOM 2300 C CB . ASN A 1 290 ? -44.919 -27.275 -15.561 1.00 14.25 ? 317 ASN A CB 1 ATOM 2301 C CG . ASN A 1 290 ? -44.088 -28.334 -16.249 1.00 18.09 ? 317 ASN A CG 1 ATOM 2302 O OD1 . ASN A 1 290 ? -43.133 -28.020 -16.958 1.00 18.87 ? 317 ASN A OD1 1 ATOM 2303 N ND2 . ASN A 1 290 ? -44.444 -29.599 -16.043 1.00 19.04 ? 317 ASN A ND2 1 ATOM 2304 N N . GLN A 1 291 ? -44.958 -25.563 -12.284 1.00 15.49 ? 318 GLN A N 1 ATOM 2305 C CA . GLN A 1 291 ? -45.706 -24.586 -11.503 1.00 14.56 ? 318 GLN A CA 1 ATOM 2306 C C . GLN A 1 291 ? -44.863 -23.354 -11.163 1.00 18.23 ? 318 GLN A C 1 ATOM 2307 O O . GLN A 1 291 ? -44.079 -23.370 -10.209 1.00 19.33 ? 318 GLN A O 1 ATOM 2308 C CB . GLN A 1 291 ? -46.222 -25.239 -10.223 1.00 13.72 ? 318 GLN A CB 1 ATOM 2309 C CG . GLN A 1 291 ? -47.503 -26.017 -10.404 1.00 13.97 ? 318 GLN A CG 1 ATOM 2310 C CD . GLN A 1 291 ? -48.704 -25.104 -10.519 1.00 18.30 ? 318 GLN A CD 1 ATOM 2311 O OE1 . GLN A 1 291 ? -48.587 -23.883 -10.380 1.00 16.28 ? 318 GLN A OE1 1 ATOM 2312 N NE2 . GLN A 1 291 ? -49.870 -25.688 -10.768 1.00 19.88 ? 318 GLN A NE2 1 ATOM 2313 N N . PRO A 1 292 ? -45.032 -22.275 -11.939 1.00 15.22 ? 319 PRO A N 1 ATOM 2314 C CA . PRO A 1 292 ? -44.230 -21.048 -11.840 1.00 14.15 ? 319 PRO A CA 1 ATOM 2315 C C . PRO A 1 292 ? -44.344 -20.249 -10.533 1.00 15.83 ? 319 PRO A C 1 ATOM 2316 O O . PRO A 1 292 ? -43.504 -19.382 -10.299 1.00 23.14 ? 319 PRO A O 1 ATOM 2317 C CB . PRO A 1 292 ? -44.741 -20.203 -13.012 1.00 18.68 ? 319 PRO A CB 1 ATOM 2318 C CG . PRO A 1 292 ? -46.099 -20.752 -13.321 1.00 20.05 ? 319 PRO A CG 1 ATOM 2319 C CD . PRO A 1 292 ? -45.994 -22.214 -13.051 1.00 15.20 ? 319 PRO A CD 1 ATOM 2320 N N . GLU A 1 293 ? -45.344 -20.512 -9.699 1.00 16.39 ? 320 GLU A N 1 ATOM 2321 C CA . GLU A 1 293 ? -45.508 -19.723 -8.479 1.00 15.09 ? 320 GLU A CA 1 ATOM 2322 C C . GLU A 1 293 ? -45.573 -20.579 -7.216 1.00 15.26 ? 320 GLU A C 1 ATOM 2323 O O . GLU A 1 293 ? -45.661 -20.050 -6.106 1.00 13.91 ? 320 GLU A O 1 ATOM 2324 C CB . GLU A 1 293 ? -46.754 -18.836 -8.574 1.00 18.80 ? 320 GLU A CB 1 ATOM 2325 C CG . GLU A 1 293 ? -46.609 -17.623 -9.490 1.00 27.61 ? 320 GLU A CG 1 ATOM 2326 C CD . GLU A 1 293 ? -47.952 -16.979 -9.839 1.00 34.92 ? 320 GLU A CD 1 ATOM 2327 O OE1 . GLU A 1 293 ? -48.978 -17.353 -9.223 1.00 27.67 ? 320 GLU A OE1 1 ATOM 2328 O OE2 . GLU A 1 293 ? -47.978 -16.104 -10.737 1.00 30.84 1 320 GLU A OE2 1 ATOM 2329 N N . LEU A 1 294 ? -45.524 -21.898 -7.389 1.00 15.22 ? 321 LEU A N 1 ATOM 2330 C CA . LEU A 1 294 ? -45.682 -22.831 -6.275 1.00 13.51 ? 321 LEU A CA 1 ATOM 2331 C C . LEU A 1 294 ? -44.565 -22.690 -5.259 1.00 13.50 ? 321 LEU A C 1 ATOM 2332 O O . LEU A 1 294 ? -43.391 -22.769 -5.608 1.00 17.64 ? 321 LEU A O 1 ATOM 2333 C CB . LEU A 1 294 ? -45.751 -24.272 -6.785 1.00 11.68 ? 321 LEU A CB 1 ATOM 2334 C CG . LEU A 1 294 ? -45.856 -25.405 -5.764 1.00 10.25 ? 321 LEU A CG 1 ATOM 2335 C CD1 . LEU A 1 294 ? -46.832 -25.070 -4.652 1.00 10.07 ? 321 LEU A CD1 1 ATOM 2336 C CD2 . LEU A 1 294 ? -46.280 -26.680 -6.474 1.00 11.13 ? 321 LEU A CD2 1 ATOM 2337 N N . GLN A 1 295 ? -44.938 -22.485 -4.001 1.00 11.41 ? 322 GLN A N 1 ATOM 2338 C CA . GLN A 1 295 ? -43.957 -22.310 -2.941 1.00 12.08 ? 322 GLN A CA 1 ATOM 2339 C C . GLN A 1 295 ? -44.084 -23.360 -1.843 1.00 13.92 ? 322 GLN A C 1 ATOM 2340 O O . GLN A 1 295 ? -43.425 -24.395 -1.883 1.00 17.05 ? 322 GLN A O 1 ATOM 2341 C CB . GLN A 1 295 ? -44.053 -20.907 -2.351 1.00 10.64 ? 322 GLN A CB 1 ATOM 2342 C CG . GLN A 1 295 ? -43.605 -19.835 -3.308 1.00 14.94 ? 322 GLN A CG 1 ATOM 2343 C CD . GLN A 1 295 ? -43.290 -18.532 -2.609 1.00 23.55 ? 322 GLN A CD 1 ATOM 2344 O OE1 . GLN A 1 295 ? -43.964 -18.149 -1.651 1.00 23.68 ? 322 GLN A OE1 1 ATOM 2345 N NE2 . GLN A 1 295 ? -42.254 -17.841 -3.083 1.00 26.35 ? 322 GLN A NE2 1 ATOM 2346 N N . ILE A 1 296 ? -44.930 -23.086 -0.861 1.00 11.66 ? 323 ILE A N 1 ATOM 2347 C CA . ILE A 1 296 ? -45.124 -23.987 0.265 1.00 8.92 ? 323 ILE A CA 1 ATOM 2348 C C . ILE A 1 296 ? -45.825 -25.275 -0.169 1.00 8.29 ? 323 ILE A C 1 ATOM 2349 O O . ILE A 1 296 ? -46.682 -25.265 -1.042 1.00 9.85 ? 323 ILE A O 1 ATOM 2350 C CB . ILE A 1 296 ? -45.926 -23.273 1.362 1.00 8.95 ? 323 ILE A CB 1 ATOM 2351 C CG1 . ILE A 1 296 ? -45.202 -21.989 1.763 1.00 9.84 ? 323 ILE A CG1 1 ATOM 2352 C CG2 . ILE A 1 296 ? -46.165 -24.176 2.562 1.00 8.97 ? 323 ILE A CG2 1 ATOM 2353 C CD1 . ILE A 1 296 ? -46.099 -20.957 2.372 1.00 12.53 ? 323 ILE A CD1 1 ATOM 2354 N N . LEU A 1 297 ? -45.429 -26.390 0.424 1.00 8.21 ? 324 LEU A N 1 ATOM 2355 C CA . LEU A 1 297 ? -46.090 -27.663 0.179 1.00 8.04 ? 324 LEU A CA 1 ATOM 2356 C C . LEU A 1 297 ? -46.138 -28.476 1.468 1.00 7.96 ? 324 LEU A C 1 ATOM 2357 O O . LEU A 1 297 ? -45.240 -28.385 2.303 1.00 8.08 ? 324 LEU A O 1 ATOM 2358 C CB . LEU A 1 297 ? -45.371 -28.437 -0.921 1.00 7.58 ? 324 LEU A CB 1 ATOM 2359 C CG . LEU A 1 297 ? -45.771 -28.088 -2.352 1.00 8.81 ? 324 LEU A CG 1 ATOM 2360 C CD1 . LEU A 1 297 ? -44.619 -28.301 -3.309 1.00 11.35 ? 324 LEU A CD1 1 ATOM 2361 C CD2 . LEU A 1 297 ? -46.941 -28.952 -2.761 1.00 10.67 ? 324 LEU A CD2 1 ATOM 2362 N N . ARG A 1 298 ? -47.205 -29.249 1.643 1.00 7.08 ? 325 ARG A N 1 ATOM 2363 C CA . ARG A 1 298 ? -47.373 -30.061 2.843 1.00 6.61 ? 325 ARG A CA 1 ATOM 2364 C C . ARG A 1 298 ? -48.001 -31.387 2.459 1.00 7.38 ? 325 ARG A C 1 ATOM 2365 O O . ARG A 1 298 ? -49.156 -31.433 2.048 1.00 7.52 ? 325 ARG A O 1 ATOM 2366 C CB . ARG A 1 298 ? -48.271 -29.362 3.861 1.00 5.35 ? 325 ARG A CB 1 ATOM 2367 C CG . ARG A 1 298 ? -47.900 -27.920 4.150 1.00 5.66 ? 325 ARG A CG 1 ATOM 2368 C CD . ARG A 1 298 ? -47.093 -27.803 5.407 1.00 5.95 ? 325 ARG A CD 1 ATOM 2369 N NE . ARG A 1 298 ? -46.752 -26.418 5.707 1.00 7.25 ? 325 ARG A NE 1 ATOM 2370 C CZ . ARG A 1 298 ? -45.582 -25.859 5.421 1.00 8.27 ? 325 ARG A CZ 1 ATOM 2371 N NH1 . ARG A 1 298 ? -44.637 -26.563 4.812 1.00 7.82 1 325 ARG A NH1 1 ATOM 2372 N NH2 . ARG A 1 298 ? -45.358 -24.593 5.744 1.00 9.53 ? 325 ARG A NH2 1 ATOM 2373 N N . LEU A 1 299 ? -47.238 -32.466 2.578 1.00 8.25 ? 326 LEU A N 1 ATOM 2374 C CA . LEU A 1 299 ? -47.723 -33.780 2.180 1.00 8.31 ? 326 LEU A CA 1 ATOM 2375 C C . LEU A 1 299 ? -47.564 -34.773 3.329 1.00 9.53 ? 326 LEU A C 1 ATOM 2376 O O . LEU A 1 299 ? -46.486 -34.911 3.902 1.00 10.90 ? 326 LEU A O 1 ATOM 2377 C CB . LEU A 1 299 ? -46.975 -34.259 0.937 1.00 8.84 ? 326 LEU A CB 1 ATOM 2378 C CG . LEU A 1 299 ? -46.682 -33.161 -0.093 1.00 8.07 ? 326 LEU A CG 1 ATOM 2379 C CD1 . LEU A 1 299 ? -45.814 -33.678 -1.219 1.00 10.89 ? 326 LEU A CD1 1 ATOM 2380 C CD2 . LEU A 1 299 ? -47.958 -32.583 -0.653 1.00 8.59 ? 326 LEU A CD2 1 ATOM 2381 N N . ARG A 1 300 ? -48.654 -35.444 3.674 1.00 8.04 ? 327 ARG A N 1 ATOM 2382 C CA . ARG A 1 300 ? -48.637 -36.458 4.717 1.00 9.86 ? 327 ARG A CA 1 ATOM 2383 C C . ARG A 1 300 ? -49.798 -37.416 4.502 1.00 11.28 ? 327 ARG A C 1 ATOM 2384 O O . ARG A 1 300 ? -50.906 -37.195 4.994 1.00 10.76 ? 327 ARG A O 1 ATOM 2385 C CB . ARG A 1 300 ? -48.717 -35.833 6.114 1.00 9.37 ? 327 ARG A CB 1 ATOM 2386 C CG . ARG A 1 300 ? -48.758 -36.875 7.218 1.00 8.65 ? 327 ARG A CG 1 ATOM 2387 C CD . ARG A 1 300 ? -48.896 -36.274 8.595 1.00 8.56 ? 327 ARG A CD 1 ATOM 2388 N NE . ARG A 1 300 ? -48.952 -37.340 9.591 1.00 11.37 ? 327 ARG A NE 1 ATOM 2389 C CZ . ARG A 1 300 ? -48.889 -37.156 10.906 1.00 11.16 ? 327 ARG A CZ 1 ATOM 2390 N NH1 . ARG A 1 300 ? -48.761 -35.933 11.406 1.00 11.73 1 327 ARG A NH1 1 ATOM 2391 N NH2 . ARG A 1 300 ? -48.954 -38.202 11.721 1.00 7.42 ? 327 ARG A NH2 1 ATOM 2392 N N . ALA A 1 301 ? -49.540 -38.475 3.750 1.00 10.30 ? 328 ALA A N 1 ATOM 2393 C CA . ALA A 1 301 ? -50.569 -39.451 3.449 1.00 10.73 ? 328 ALA A CA 1 ATOM 2394 C C . ALA A 1 301 ? -50.003 -40.855 3.555 1.00 16.10 ? 328 ALA A C 1 ATOM 2395 O O . ALA A 1 301 ? -50.504 -41.779 2.916 1.00 17.35 ? 328 ALA A O 1 ATOM 2396 C CB . ALA A 1 301 ? -51.118 -39.210 2.069 1.00 12.31 ? 328 ALA A CB 1 ATOM 2397 N N . GLU A 1 302 ? -48.964 -41.002 4.376 1.00 19.29 ? 329 GLU A N 1 ATOM 2398 C CA . GLU A 1 302 ? -48.204 -42.248 4.480 1.00 17.56 ? 329 GLU A CA 1 ATOM 2399 C C . GLU A 1 302 ? -47.687 -42.661 3.111 1.00 15.75 ? 329 GLU A C 1 ATOM 2400 O O . GLU A 1 302 ? -47.827 -43.810 2.692 1.00 15.33 ? 329 GLU A O 1 ATOM 2401 C CB . GLU A 1 302 ? -49.039 -43.357 5.115 1.00 16.59 ? 329 GLU A CB 1 ATOM 2402 C CG . GLU A 1 302 ? -49.633 -42.956 6.445 1.00 23.96 ? 329 GLU A CG 1 ATOM 2403 C CD . GLU A 1 302 ? -50.179 -44.135 7.214 1.00 40.69 ? 329 GLU A CD 1 ATOM 2404 O OE1 . GLU A 1 302 ? -51.100 -43.929 8.033 1.00 57.56 ? 329 GLU A OE1 1 ATOM 2405 O OE2 . GLU A 1 302 ? -49.683 -45.266 7.005 1.00 31.76 1 329 GLU A OE2 1 ATOM 2406 N N . LEU A 1 303 ? -47.099 -41.696 2.416 1.00 15.50 ? 330 LEU A N 1 ATOM 2407 C CA . LEU A 1 303 ? -46.563 -41.928 1.090 1.00 18.73 ? 330 LEU A CA 1 ATOM 2408 C C . LEU A 1 303 ? -45.416 -42.921 1.158 1.00 24.61 ? 330 LEU A C 1 ATOM 2409 O O . LEU A 1 303 ? -44.608 -42.881 2.089 1.00 22.37 ? 330 LEU A O 1 ATOM 2410 C CB . LEU A 1 303 ? -46.075 -40.620 0.471 1.00 19.14 ? 330 LEU A CB 1 ATOM 2411 C CG . LEU A 1 303 ? -47.129 -39.629 -0.015 1.00 19.14 ? 330 LEU A CG 1 ATOM 2412 C CD1 . LEU A 1 303 ? -47.639 -38.768 1.127 1.00 17.56 ? 330 LEU A CD1 1 ATOM 2413 C CD2 . LEU A 1 303 ? -46.549 -38.766 -1.116 1.00 19.92 ? 330 LEU A CD2 1 ATOM 2414 N N . GLN A 1 304 ? -45.345 -43.799 0.160 1.00 25.79 ? 331 GLN A N 1 ATOM 2415 C CA . GLN A 1 304 ? -44.312 -44.826 0.108 1.00 21.14 ? 331 GLN A CA 1 ATOM 2416 C C . GLN A 1 304 ? -43.178 -44.472 -0.849 1.00 18.96 ? 331 GLN A C 1 ATOM 2417 O O . GLN A 1 304 ? -42.053 -44.931 -0.674 1.00 21.08 ? 331 GLN A O 1 ATOM 2418 C CB . GLN A 1 304 ? -44.924 -46.169 -0.278 1.00 17.80 ? 331 GLN A CB 1 ATOM 2419 C CG . GLN A 1 304 ? -46.057 -46.588 0.630 1.00 20.15 ? 331 GLN A CG 1 ATOM 2420 C CD . GLN A 1 304 ? -46.513 -48.006 0.373 1.00 25.49 ? 331 GLN A CD 1 ATOM 2421 O OE1 . GLN A 1 304 ? -46.567 -48.458 -0.770 1.00 23.14 ? 331 GLN A OE1 1 ATOM 2422 N NE2 . GLN A 1 304 ? -46.834 -48.722 1.442 1.00 32.18 ? 331 GLN A NE2 1 ATOM 2423 N N . SER A 1 305 ? -43.473 -43.657 -1.855 1.00 17.84 ? 332 SER A N 1 ATOM 2424 C CA . SER A 1 305 ? -42.475 -43.300 -2.859 1.00 19.81 ? 332 SER A CA 1 ATOM 2425 C C . SER A 1 305 ? -42.858 -42.028 -3.602 1.00 24.26 ? 332 SER A C 1 ATOM 2426 O O . SER A 1 305 ? -43.972 -41.526 -3.460 1.00 26.22 ? 332 SER A O 1 ATOM 2427 C CB . SER A 1 305 ? -42.281 -44.447 -3.857 1.00 22.38 ? 332 SER A CB 1 ATOM 2428 O OG . SER A 1 305 ? -43.520 -44.909 -4.374 1.00 19.45 ? 332 SER A OG 1 ATOM 2429 N N . LEU A 1 306 ? -41.928 -41.509 -4.396 1.00 20.97 ? 333 LEU A N 1 ATOM 2430 C CA . LEU A 1 306 ? -42.168 -40.284 -5.145 1.00 20.75 ? 333 LEU A CA 1 ATOM 2431 C C . LEU A 1 306 ? -41.530 -40.369 -6.527 1.00 25.56 ? 333 LEU A C 1 ATOM 2432 O O . LEU A 1 306 ? -40.541 -41.078 -6.716 1.00 29.26 ? 333 LEU A O 1 ATOM 2433 C CB . LEU A 1 306 ? -41.608 -39.075 -4.387 1.00 17.66 ? 333 LEU A CB 1 ATOM 2434 C CG . LEU A 1 306 ? -42.168 -38.787 -2.991 1.00 17.29 ? 333 LEU A CG 1 ATOM 2435 C CD1 . LEU A 1 306 ? -41.326 -37.753 -2.277 1.00 16.76 ? 333 LEU A CD1 1 ATOM 2436 C CD2 . LEU A 1 306 ? -43.609 -38.329 -3.064 1.00 15.95 ? 333 LEU A CD2 1 ATOM 2437 N N . PRO A 1 307 ? -42.111 -39.661 -7.505 1.00 25.77 ? 334 PRO A N 1 ATOM 2438 C CA . PRO A 1 307 ? -41.518 -39.512 -8.838 1.00 28.24 ? 334 PRO A CA 1 ATOM 2439 C C . PRO A 1 307 ? -40.504 -38.379 -8.851 1.00 26.92 ? 334 PRO A C 1 ATOM 2440 O O . PRO A 1 307 ? -40.719 -37.375 -8.178 1.00 27.06 ? 334 PRO A O 1 ATOM 2441 C CB . PRO A 1 307 ? -42.718 -39.133 -9.702 1.00 34.97 ? 334 PRO A CB 1 ATOM 2442 C CG . PRO A 1 307 ? -43.617 -38.403 -8.771 1.00 33.08 ? 334 PRO A CG 1 ATOM 2443 C CD . PRO A 1 307 ? -43.466 -39.088 -7.438 1.00 27.19 ? 334 PRO A CD 1 ATOM 2444 N N . GLY A 1 308 ? -39.420 -38.534 -9.604 1.00 26.78 ? 335 GLY A N 1 ATOM 2445 C CA . GLY A 1 308 ? -38.385 -37.516 -9.650 1.00 30.18 ? 335 GLY A CA 1 ATOM 2446 C C . GLY A 1 308 ? -38.891 -36.224 -10.259 1.00 34.45 ? 335 GLY A C 1 ATOM 2447 O O . GLY A 1 308 ? -38.431 -35.128 -9.916 1.00 26.59 ? 335 GLY A O 1 ATOM 2448 N N . ASP A 1 309 ? -39.859 -36.361 -11.162 1.00 33.99 ? 336 ASP A N 1 ATOM 2449 C CA . ASP A 1 309 ? -40.433 -35.220 -11.860 1.00 32.52 ? 336 ASP A CA 1 ATOM 2450 C C . ASP A 1 309 ? -41.612 -34.619 -11.098 1.00 32.18 ? 336 ASP A C 1 ATOM 2451 O O . ASP A 1 309 ? -42.395 -33.862 -11.667 1.00 33.88 ? 336 ASP A O 1 ATOM 2452 C CB . ASP A 1 309 ? -40.866 -35.614 -13.281 1.00 37.80 ? 336 ASP A CB 1 ATOM 2453 C CG . ASP A 1 309 ? -41.847 -36.784 -13.299 1.00 40.04 ? 336 ASP A CG 1 ATOM 2454 O OD1 . ASP A 1 309 ? -42.961 -36.643 -12.750 1.00 43.21 ? 336 ASP A OD1 1 ATOM 2455 O OD2 . ASP A 1 309 ? -41.514 -37.840 -13.883 1.00 33.75 1 336 ASP A OD2 1 ATOM 2456 N N . LEU A 1 310 ? -41.737 -34.964 -9.818 1.00 32.54 ? 337 LEU A N 1 ATOM 2457 C CA . LEU A 1 310 ? -42.831 -34.462 -8.987 1.00 24.74 ? 337 LEU A CA 1 ATOM 2458 C C . LEU A 1 310 ? -42.806 -32.944 -8.855 1.00 19.65 ? 337 LEU A C 1 ATOM 2459 O O . LEU A 1 310 ? -43.857 -32.311 -8.814 1.00 20.15 ? 337 LEU A O 1 ATOM 2460 C CB . LEU A 1 310 ? -42.797 -35.092 -7.594 1.00 21.47 ? 337 LEU A CB 1 ATOM 2461 C CG . LEU A 1 310 ? -43.962 -34.717 -6.675 1.00 20.00 ? 337 LEU A CG 1 ATOM 2462 C CD1 . LEU A 1 310 ? -45.230 -35.437 -7.096 1.00 25.22 ? 337 LEU A CD1 1 ATOM 2463 C CD2 . LEU A 1 310 ? -43.635 -35.019 -5.229 1.00 19.98 ? 337 LEU A CD2 1 ATOM 2464 N N . PHE A 1 311 ? -41.610 -32.364 -8.784 1.00 16.02 ? 338 PHE A N 1 ATOM 2465 C CA . PHE A 1 311 ? -41.482 -30.918 -8.680 1.00 14.49 ? 338 PHE A CA 1 ATOM 2466 C C . PHE A 1 311 ? -40.767 -30.324 -9.883 1.00 17.66 ? 338 PHE A C 1 ATOM 2467 O O . PHE A 1 311 ? -40.279 -29.196 -9.815 1.00 16.94 ? 338 PHE A O 1 ATOM 2468 C CB . PHE A 1 311 ? -40.723 -30.523 -7.416 1.00 16.31 ? 338 PHE A CB 1 ATOM 2469 C CG . PHE A 1 311 ? -41.278 -31.112 -6.156 1.00 17.85 ? 338 PHE A CG 1 ATOM 2470 C CD1 . PHE A 1 311 ? -42.499 -30.693 -5.658 1.00 17.57 ? 338 PHE A CD1 1 ATOM 2471 C CD2 . PHE A 1 311 ? -40.565 -32.070 -5.454 1.00 20.02 ? 338 PHE A CD2 1 ATOM 2472 C CE1 . PHE A 1 311 ? -43.010 -31.232 -4.489 1.00 18.03 ? 338 PHE A CE1 1 ATOM 2473 C CE2 . PHE A 1 311 ? -41.067 -32.615 -4.283 1.00 19.42 ? 338 PHE A CE2 1 ATOM 2474 C CZ . PHE A 1 311 ? -42.290 -32.193 -3.798 1.00 19.94 ? 338 PHE A CZ 1 ATOM 2475 N N . GLU A 1 312 ? -40.709 -31.081 -10.978 1.00 21.46 ? 339 GLU A N 1 ATOM 2476 C CA . GLU A 1 312 ? -39.961 -30.680 -12.175 1.00 22.23 ? 339 GLU A CA 1 ATOM 2477 C C . GLU A 1 312 ? -40.331 -29.288 -12.690 1.00 19.38 ? 339 GLU A C 1 ATOM 2478 O O . GLU A 1 312 ? -41.497 -29.004 -12.932 1.00 21.29 ? 339 GLU A O 1 ATOM 2479 C CB . GLU A 1 312 ? -40.129 -31.719 -13.287 1.00 21.71 ? 339 GLU A CB 1 ATOM 2480 C CG . GLU A 1 312 ? -39.341 -31.404 -14.548 1.00 32.30 ? 339 GLU A CG 1 ATOM 2481 C CD . GLU A 1 312 ? -39.398 -32.525 -15.577 1.00 45.99 ? 339 GLU A CD 1 ATOM 2482 O OE1 . GLU A 1 312 ? -39.182 -32.244 -16.779 1.00 42.45 ? 339 GLU A OE1 1 ATOM 2483 O OE2 . GLU A 1 312 ? -39.652 -33.686 -15.184 1.00 46.01 1 339 GLU A OE2 1 ATOM 2484 N N . HIS A 1 313 ? -39.322 -28.431 -12.835 1.00 19.99 ? 340 HIS A N 1 ATOM 2485 C CA . HIS A 1 313 ? -39.479 -27.044 -13.298 1.00 22.07 ? 340 HIS A CA 1 ATOM 2486 C C . HIS A 1 313 ? -40.202 -26.103 -12.325 1.00 19.46 ? 340 HIS A C 1 ATOM 2487 O O . HIS A 1 313 ? -40.522 -24.969 -12.682 1.00 19.68 ? 340 HIS A O 1 ATOM 2488 C CB . HIS A 1 313 ? -40.140 -26.976 -14.682 1.00 24.20 ? 340 HIS A CB 1 ATOM 2489 C CG . HIS A 1 313 ? -39.390 -27.711 -15.749 1.00 30.84 ? 340 HIS A CG 1 ATOM 2490 N ND1 . HIS A 1 313 ? -40.022 -28.395 -16.765 1.00 34.19 ? 340 HIS A ND1 1 ATOM 2491 C CD2 . HIS A 1 313 ? -38.062 -27.868 -15.959 1.00 32.67 ? 340 HIS A CD2 1 ATOM 2492 C CE1 . HIS A 1 313 ? -39.116 -28.946 -17.553 1.00 34.24 ? 340 HIS A CE1 1 ATOM 2493 N NE2 . HIS A 1 313 ? -37.919 -28.641 -17.087 1.00 39.98 ? 340 HIS A NE2 1 ATOM 2494 N N . SER A 1 314 ? -40.452 -26.560 -11.103 1.00 19.71 ? 341 SER A N 1 ATOM 2495 C CA . SER A 1 314 ? -41.140 -25.725 -10.118 1.00 20.62 ? 341 SER A CA 1 ATOM 2496 C C . SER A 1 314 ? -40.130 -24.982 -9.252 1.00 21.42 ? 341 SER A C 1 ATOM 2497 O O . SER A 1 314 ? -40.084 -25.144 -8.033 1.00 21.13 ? 341 SER A O 1 ATOM 2498 C CB . SER A 1 314 ? -42.093 -26.562 -9.257 1.00 20.64 ? 341 SER A CB 1 ATOM 2499 O OG . SER A 1 314 ? -43.185 -27.053 -10.024 1.00 19.86 ? 341 SER A OG 1 ATOM 2500 N N . THR A 1 315 ? -39.336 -24.141 -9.901 1.00 20.89 ? 342 THR A N 1 ATOM 2501 C CA . THR A 1 315 ? -38.163 -23.536 -9.283 1.00 22.69 ? 342 THR A CA 1 ATOM 2502 C C . THR A 1 315 ? -38.466 -22.459 -8.240 1.00 22.66 ? 342 THR A C 1 ATOM 2503 O O . THR A 1 315 ? -37.628 -21.592 -7.977 1.00 21.69 ? 342 THR A O 1 ATOM 2504 C CB . THR A 1 315 ? -37.270 -22.906 -10.357 1.00 22.81 ? 342 THR A CB 1 ATOM 2505 O OG1 . THR A 1 315 ? -37.432 -21.482 -10.335 1.00 27.65 ? 342 THR A OG1 1 ATOM 2506 C CG2 . THR A 1 315 ? -37.644 -23.442 -11.735 1.00 16.75 ? 342 THR A CG2 1 ATOM 2507 N N . GLN A 1 316 ? -39.648 -22.507 -7.637 1.00 17.80 ? 343 GLN A N 1 ATOM 2508 C CA . GLN A 1 316 ? -40.016 -21.467 -6.690 1.00 19.51 ? 343 GLN A CA 1 ATOM 2509 C C . GLN A 1 316 ? -40.308 -21.979 -5.286 1.00 17.70 ? 343 GLN A C 1 ATOM 2510 O O . GLN A 1 316 ? -40.357 -21.196 -4.334 1.00 15.03 ? 343 GLN A O 1 ATOM 2511 C CB . GLN A 1 316 ? -41.193 -20.650 -7.215 1.00 19.41 ? 343 GLN A CB 1 ATOM 2512 C CG . GLN A 1 316 ? -40.975 -19.172 -7.038 1.00 22.84 ? 343 GLN A CG 1 ATOM 2513 C CD . GLN A 1 316 ? -39.585 -18.773 -7.473 1.00 30.77 ? 343 GLN A CD 1 ATOM 2514 O OE1 . GLN A 1 316 ? -39.160 -19.088 -8.587 1.00 27.16 ? 343 GLN A OE1 1 ATOM 2515 N NE2 . GLN A 1 316 ? -38.857 -18.099 -6.588 1.00 31.01 ? 343 GLN A NE2 1 ATOM 2516 N N . ILE A 1 317 ? -40.502 -23.290 -5.172 1.00 12.80 ? 344 ILE A N 1 ATOM 2517 C CA . ILE A 1 317 ? -40.792 -23.928 -3.898 1.00 10.23 ? 344 ILE A CA 1 ATOM 2518 C C . ILE A 1 317 ? -39.846 -23.443 -2.809 1.00 11.30 ? 344 ILE A C 1 ATOM 2519 O O . ILE A 1 317 ? -38.644 -23.363 -3.024 1.00 13.59 ? 344 ILE A O 1 ATOM 2520 C CB . ILE A 1 317 ? -40.669 -25.449 -4.023 1.00 11.07 ? 344 ILE A CB 1 ATOM 2521 C CG1 . ILE A 1 317 ? -41.578 -25.960 -5.138 1.00 12.53 ? 344 ILE A CG1 1 ATOM 2522 C CG2 . ILE A 1 317 ? -41.001 -26.128 -2.708 1.00 10.27 ? 344 ILE A CG2 1 ATOM 2523 C CD1 . ILE A 1 317 ? -41.474 -27.448 -5.364 1.00 14.48 ? 344 ILE A CD1 1 ATOM 2524 N N . THR A 1 318 ? -40.391 -23.094 -1.648 1.00 11.36 ? 345 THR A N 1 ATOM 2525 C CA . THR A 1 318 ? -39.558 -22.653 -0.535 1.00 11.02 ? 345 THR A CA 1 ATOM 2526 C C . THR A 1 318 ? -39.620 -23.597 0.670 1.00 13.95 ? 345 THR A C 1 ATOM 2527 O O . THR A 1 318 ? -38.603 -23.846 1.309 1.00 15.51 ? 345 THR A O 1 ATOM 2528 C CB . THR A 1 318 ? -39.912 -21.236 -0.075 1.00 9.14 ? 345 THR A CB 1 ATOM 2529 O OG1 . THR A 1 318 ? -41.233 -21.232 0.477 1.00 10.54 ? 345 THR A OG1 1 ATOM 2530 C CG2 . THR A 1 318 ? -39.836 -20.264 -1.238 1.00 11.25 ? 345 THR A CG2 1 ATOM 2531 N N . ASN A 1 319 ? -40.806 -24.095 1.008 1.00 12.08 ? 346 ASN A N 1 ATOM 2532 C CA . ASN A 1 319 ? -40.914 -25.094 2.070 1.00 11.01 ? 346 ASN A CA 1 ATOM 2533 C C . ASN A 1 319 ? -41.555 -26.381 1.567 1.00 9.19 ? 346 ASN A C 1 ATOM 2534 O O . ASN A 1 319 ? -42.420 -26.338 0.703 1.00 9.61 ? 346 ASN A O 1 ATOM 2535 C CB . ASN A 1 319 ? -41.699 -24.555 3.268 1.00 10.68 ? 346 ASN A CB 1 ATOM 2536 C CG . ASN A 1 319 ? -41.226 -23.190 3.708 1.00 11.31 ? 346 ASN A CG 1 ATOM 2537 O OD1 . ASN A 1 319 ? -40.885 -22.354 2.883 1.00 12.16 ? 346 ASN A OD1 1 ATOM 2538 N ND2 . ASN A 1 319 ? -41.207 -22.956 5.014 1.00 15.68 ? 346 ASN A ND2 1 ATOM 2539 N N . ILE A 1 320 ? -41.118 -27.522 2.097 1.00 8.42 ? 347 ILE A N 1 ATOM 2540 C CA . ILE A 1 320 ? -41.741 -28.812 1.802 1.00 7.37 ? 347 ILE A CA 1 ATOM 2541 C C . ILE A 1 320 ? -41.820 -29.628 3.074 1.00 7.04 ? 347 ILE A C 1 ATOM 2542 O O . ILE A 1 320 ? -40.819 -29.794 3.760 1.00 8.60 ? 347 ILE A O 1 ATOM 2543 C CB . ILE A 1 320 ? -40.939 -29.642 0.780 1.00 7.00 ? 347 ILE A CB 1 ATOM 2544 C CG1 . ILE A 1 320 ? -41.032 -29.018 -0.608 1.00 9.13 ? 347 ILE A CG1 1 ATOM 2545 C CG2 . ILE A 1 320 ? -41.452 -31.083 0.733 1.00 5.71 ? 347 ILE A CG2 1 ATOM 2546 C CD1 . ILE A 1 320 ? -40.438 -29.872 -1.697 1.00 10.44 ? 347 ILE A CD1 1 ATOM 2547 N N . SER A 1 321 ? -43.003 -30.134 3.395 1.00 5.91 ? 348 SER A N 1 ATOM 2548 C CA . SER A 1 321 ? -43.145 -31.007 4.544 1.00 5.38 ? 348 SER A CA 1 ATOM 2549 C C . SER A 1 321 ? -43.502 -32.398 4.074 1.00 6.67 ? 348 SER A C 1 ATOM 2550 O O . SER A 1 321 ? -44.669 -32.714 3.879 1.00 7.79 ? 348 SER A O 1 ATOM 2551 C CB . SER A 1 321 ? -44.211 -30.484 5.504 1.00 4.90 ? 348 SER A CB 1 ATOM 2552 O OG . SER A 1 321 ? -43.857 -29.218 6.027 1.00 3.79 ? 348 SER A OG 1 ATOM 2553 N N . LEU A 1 322 ? -42.486 -33.227 3.878 1.00 8.00 ? 349 LEU A N 1 ATOM 2554 C CA . LEU A 1 322 ? -42.702 -34.631 3.556 1.00 9.82 ? 349 LEU A CA 1 ATOM 2555 C C . LEU A 1 322 ? -42.515 -35.492 4.794 1.00 10.02 ? 349 LEU A C 1 ATOM 2556 O O . LEU A 1 322 ? -42.231 -36.689 4.707 1.00 8.78 ? 349 LEU A O 1 ATOM 2557 C CB . LEU A 1 322 ? -41.759 -35.076 2.449 1.00 8.39 ? 349 LEU A CB 1 ATOM 2558 C CG . LEU A 1 322 ? -42.317 -34.774 1.070 1.00 7.17 ? 349 LEU A CG 1 ATOM 2559 C CD1 . LEU A 1 322 ? -41.281 -35.091 0.033 1.00 9.47 ? 349 LEU A CD1 1 ATOM 2560 C CD2 . LEU A 1 322 ? -43.560 -35.607 0.862 1.00 9.18 ? 349 LEU A CD2 1 ATOM 2561 N N . GLY A 1 323 ? -42.676 -34.861 5.951 1.00 10.17 ? 350 GLY A N 1 ATOM 2562 C CA . GLY A 1 323 ? -42.581 -35.553 7.216 1.00 10.94 ? 350 GLY A CA 1 ATOM 2563 C C . GLY A 1 323 ? -43.740 -36.502 7.437 1.00 13.23 ? 350 GLY A C 1 ATOM 2564 O O . GLY A 1 323 ? -44.777 -36.396 6.781 1.00 13.04 ? 350 GLY A O 1 ATOM 2565 N N . ASP A 1 324 ? -43.545 -37.437 8.360 1.00 14.88 ? 351 ASP A N 1 ATOM 2566 C CA . ASP A 1 324 ? -44.574 -38.392 8.769 1.00 13.97 ? 351 ASP A CA 1 ATOM 2567 C C . ASP A 1 324 ? -45.131 -39.238 7.633 1.00 13.64 ? 351 ASP A C 1 ATOM 2568 O O . ASP A 1 324 ? -46.332 -39.506 7.591 1.00 17.99 ? 351 ASP A O 1 ATOM 2569 C CB . ASP A 1 324 ? -45.723 -37.683 9.487 1.00 13.88 ? 351 ASP A CB 1 ATOM 2570 C CG . ASP A 1 324 ? -45.270 -36.946 10.729 1.00 16.32 ? 351 ASP A CG 1 ATOM 2571 O OD1 . ASP A 1 324 ? -44.893 -37.618 11.718 1.00 14.27 ? 351 ASP A OD1 1 ATOM 2572 O OD2 . ASP A 1 324 ? -45.312 -35.695 10.713 1.00 17.77 1 351 ASP A OD2 1 ATOM 2573 N N . ASN A 1 325 ? -44.268 -39.650 6.712 1.00 12.49 ? 352 ASN A N 1 ATOM 2574 C CA . ASN A 1 325 ? -44.683 -40.560 5.651 1.00 15.26 ? 352 ASN A CA 1 ATOM 2575 C C . ASN A 1 325 ? -44.128 -41.960 5.858 1.00 15.54 ? 352 ASN A C 1 ATOM 2576 O O . ASN A 1 325 ? -43.883 -42.376 6.993 1.00 12.77 ? 352 ASN A O 1 ATOM 2577 C CB . ASN A 1 325 ? -44.302 -40.027 4.268 1.00 14.77 ? 352 ASN A CB 1 ATOM 2578 C CG . ASN A 1 325 ? -45.265 -38.974 3.766 1.00 13.84 ? 352 ASN A CG 1 ATOM 2579 O OD1 . ASN A 1 325 ? -46.453 -39.010 4.080 1.00 14.92 ? 352 ASN A OD1 1 ATOM 2580 N ND2 . ASN A 1 325 ? -44.759 -38.027 2.985 1.00 12.36 ? 352 ASN A ND2 1 ATOM 2581 N N . LEU A 1 326 ? -43.950 -42.685 4.757 1.00 16.40 ? 353 LEU A N 1 ATOM 2582 C CA . LEU A 1 326 ? -43.391 -44.031 4.797 1.00 18.52 ? 353 LEU A CA 1 ATOM 2583 C C . LEU A 1 326 ? -42.288 -44.185 3.766 1.00 18.68 ? 353 LEU A C 1 ATOM 2584 O O . LEU A 1 326 ? -41.979 -45.301 3.346 1.00 18.36 ? 353 LEU A O 1 ATOM 2585 C CB . LEU A 1 326 ? -44.467 -45.084 4.535 1.00 16.00 ? 353 LEU A CB 1 ATOM 2586 C CG . LEU A 1 326 ? -45.426 -45.427 5.670 1.00 16.40 ? 353 LEU A CG 1 ATOM 2587 C CD1 . LEU A 1 326 ? -46.289 -46.617 5.265 1.00 17.38 ? 353 LEU A CD1 1 ATOM 2588 C CD2 . LEU A 1 326 ? -44.662 -45.709 6.955 1.00 15.99 ? 353 LEU A CD2 1 ATOM 2589 N N . LEU A 1 327 ? -41.707 -43.059 3.359 1.00 19.47 ? 354 LEU A N 1 ATOM 2590 C CA . LEU A 1 327 ? -40.634 -43.047 2.367 1.00 21.48 ? 354 LEU A CA 1 ATOM 2591 C C . LEU A 1 327 ? -39.460 -43.925 2.795 1.00 21.20 ? 354 LEU A C 1 ATOM 2592 O O . LEU A 1 327 ? -38.961 -43.811 3.915 1.00 20.56 ? 354 LEU A O 1 ATOM 2593 C CB . LEU A 1 327 ? -40.154 -41.615 2.117 1.00 16.19 ? 354 LEU A CB 1 ATOM 2594 C CG . LEU A 1 327 ? -41.200 -40.611 1.635 1.00 15.25 ? 354 LEU A CG 1 ATOM 2595 C CD1 . LEU A 1 327 ? -40.639 -39.198 1.695 1.00 12.75 ? 354 LEU A CD1 1 ATOM 2596 C CD2 . LEU A 1 327 ? -41.684 -40.952 0.230 1.00 14.05 ? 354 LEU A CD2 1 ATOM 2597 N N . LYS A 1 328 ? -39.033 -44.812 1.904 1.00 19.59 ? 355 LYS A N 1 ATOM 2598 C CA . LYS A 1 328 ? -37.900 -45.674 2.188 1.00 20.87 ? 355 LYS A CA 1 ATOM 2599 C C . LYS A 1 328 ? -36.651 -44.953 1.729 1.00 23.61 ? 355 LYS A C 1 ATOM 2600 O O . LYS A 1 328 ? -35.616 -44.986 2.393 1.00 21.47 ? 355 LYS A O 1 ATOM 2601 C CB . LYS A 1 328 ? -38.037 -47.001 1.450 1.00 24.49 ? 355 LYS A CB 1 ATOM 2602 C CG . LYS A 1 328 ? -37.337 -48.153 2.139 1.00 28.12 ? 355 LYS A CG 1 ATOM 2603 C CD . LYS A 1 328 ? -37.898 -48.347 3.537 1.00 34.27 ? 355 LYS A CD 1 ATOM 2604 C CE . LYS A 1 328 ? -37.198 -49.477 4.274 1.00 50.35 ? 355 LYS A CE 1 ATOM 2605 N NZ . LYS A 1 328 ? -35.737 -49.238 4.415 1.00 36.34 1 355 LYS A NZ 1 ATOM 2606 N N . THR A 1 329 ? -36.766 -44.299 0.578 1.00 24.55 ? 356 THR A N 1 ATOM 2607 C CA . THR A 1 329 ? -35.701 -43.463 0.040 1.00 22.00 ? 356 THR A CA 1 ATOM 2608 C C . THR A 1 329 ? -36.338 -42.364 -0.793 1.00 18.53 ? 356 THR A C 1 ATOM 2609 O O . THR A 1 329 ? -37.558 -42.222 -0.806 1.00 20.00 ? 356 THR A O 1 ATOM 2610 C CB . THR A 1 329 ? -34.713 -44.276 -0.824 1.00 22.99 ? 356 THR A CB 1 ATOM 2611 O OG1 . THR A 1 329 ? -33.853 -43.387 -1.547 1.00 20.84 ? 356 THR A OG1 1 ATOM 2612 C CG2 . THR A 1 329 ? -35.458 -45.156 -1.811 1.00 22.55 ? 356 THR A CG2 1 ATOM 2613 N N . LEU A 1 330 ? -35.516 -41.585 -1.480 1.00 16.95 ? 357 LEU A N 1 ATOM 2614 C CA . LEU A 1 330 ? -36.019 -40.600 -2.426 1.00 19.30 ? 357 LEU A CA 1 ATOM 2615 C C . LEU A 1 330 ? -35.356 -40.781 -3.788 1.00 25.04 ? 357 LEU A C 1 ATOM 2616 O O . LEU A 1 330 ? -34.228 -41.260 -3.873 1.00 30.12 ? 357 LEU A O 1 ATOM 2617 C CB . LEU A 1 330 ? -35.761 -39.189 -1.910 1.00 18.13 ? 357 LEU A CB 1 ATOM 2618 C CG . LEU A 1 330 ? -36.599 -38.760 -0.710 1.00 16.20 ? 357 LEU A CG 1 ATOM 2619 C CD1 . LEU A 1 330 ? -36.343 -37.302 -0.396 1.00 17.58 ? 357 LEU A CD1 1 ATOM 2620 C CD2 . LEU A 1 330 ? -38.065 -38.984 -0.997 1.00 17.60 ? 357 LEU A CD2 1 ATOM 2621 N N . PRO A 1 331 ? -36.060 -40.417 -4.867 1.00 24.63 ? 358 PRO A N 1 ATOM 2622 C CA . PRO A 1 331 ? -35.368 -40.396 -6.158 1.00 25.68 ? 358 PRO A CA 1 ATOM 2623 C C . PRO A 1 331 ? -34.360 -39.254 -6.154 1.00 24.07 ? 358 PRO A C 1 ATOM 2624 O O . PRO A 1 331 ? -34.557 -38.276 -5.432 1.00 20.66 ? 358 PRO A O 1 ATOM 2625 C CB . PRO A 1 331 ? -36.496 -40.137 -7.160 1.00 23.66 ? 358 PRO A CB 1 ATOM 2626 C CG . PRO A 1 331 ? -37.561 -39.466 -6.364 1.00 26.04 ? 358 PRO A CG 1 ATOM 2627 C CD . PRO A 1 331 ? -37.482 -40.057 -4.988 1.00 23.18 ? 358 PRO A CD 1 ATOM 2628 N N . ALA A 1 332 ? -33.293 -39.381 -6.934 1.00 25.52 ? 359 ALA A N 1 ATOM 2629 C CA . ALA A 1 332 ? -32.180 -38.440 -6.848 1.00 28.98 ? 359 ALA A CA 1 ATOM 2630 C C . ALA A 1 332 ? -32.515 -37.078 -7.436 1.00 25.54 ? 359 ALA A C 1 ATOM 2631 O O . ALA A 1 332 ? -32.077 -36.045 -6.928 1.00 22.35 ? 359 ALA A O 1 ATOM 2632 C CB . ALA A 1 332 ? -30.938 -39.019 -7.519 1.00 33.08 ? 359 ALA A CB 1 ATOM 2633 N N . THR A 1 333 ? -33.301 -37.085 -8.506 1.00 27.30 ? 360 THR A N 1 ATOM 2634 C CA . THR A 1 333 ? -33.590 -35.870 -9.257 1.00 26.85 ? 360 THR A CA 1 ATOM 2635 C C . THR A 1 333 ? -34.655 -35.012 -8.597 1.00 27.91 ? 360 THR A C 1 ATOM 2636 O O . THR A 1 333 ? -34.865 -33.868 -8.999 1.00 29.85 ? 360 THR A O 1 ATOM 2637 C CB . THR A 1 333 ? -34.077 -36.215 -10.659 1.00 22.83 ? 360 THR A CB 1 ATOM 2638 O OG1 . THR A 1 333 ? -34.164 -37.640 -10.783 1.00 18.93 ? 360 THR A OG1 1 ATOM 2639 C CG2 . THR A 1 333 ? -33.119 -35.656 -11.706 1.00 21.83 ? 360 THR A CG2 1 ATOM 2640 N N . LEU A 1 334 ? -35.308 -35.572 -7.581 1.00 27.78 ? 361 LEU A N 1 ATOM 2641 C CA . LEU A 1 334 ? -36.492 -34.978 -6.964 1.00 26.50 ? 361 LEU A CA 1 ATOM 2642 C C . LEU A 1 334 ? -36.378 -33.488 -6.665 1.00 26.43 ? 361 LEU A C 1 ATOM 2643 O O . LEU A 1 334 ? -37.363 -32.755 -6.764 1.00 31.35 ? 361 LEU A O 1 ATOM 2644 C CB . LEU A 1 334 ? -36.869 -35.733 -5.689 1.00 23.65 ? 361 LEU A CB 1 ATOM 2645 C CG . LEU A 1 334 ? -38.124 -35.217 -4.983 1.00 24.98 ? 361 LEU A CG 1 ATOM 2646 C CD1 . LEU A 1 334 ? -39.340 -35.350 -5.887 1.00 25.31 ? 361 LEU A CD1 1 ATOM 2647 C CD2 . LEU A 1 334 ? -38.345 -35.945 -3.670 1.00 27.63 ? 361 LEU A CD2 1 ATOM 2648 N N . LEU A 1 335 ? -35.182 -33.031 -6.319 1.00 19.54 ? 362 LEU A N 1 ATOM 2649 C CA . LEU A 1 335 ? -35.007 -31.618 -6.015 1.00 23.95 ? 362 LEU A CA 1 ATOM 2650 C C . LEU A 1 335 ? -34.016 -30.921 -6.941 1.00 27.31 ? 362 LEU A C 1 ATOM 2651 O O . LEU A 1 335 ? -33.349 -29.970 -6.535 1.00 26.97 ? 362 LEU A O 1 ATOM 2652 C CB . LEU A 1 335 ? -34.608 -31.433 -4.552 1.00 20.93 ? 362 LEU A CB 1 ATOM 2653 C CG . LEU A 1 335 ? -35.672 -31.899 -3.559 1.00 19.23 ? 362 LEU A CG 1 ATOM 2654 C CD1 . LEU A 1 335 ? -35.181 -31.751 -2.148 1.00 17.16 ? 362 LEU A CD1 1 ATOM 2655 C CD2 . LEU A 1 335 ? -36.942 -31.101 -3.750 1.00 26.26 ? 362 LEU A CD2 1 ATOM 2656 N N . GLU A 1 336 ? -33.940 -31.384 -8.188 1.00 28.89 ? 363 GLU A N 1 ATOM 2657 C CA . GLU A 1 336 ? -32.990 -30.833 -9.154 1.00 27.31 ? 363 GLU A CA 1 ATOM 2658 C C . GLU A 1 336 ? -33.180 -29.339 -9.413 1.00 31.11 ? 363 GLU A C 1 ATOM 2659 O O . GLU A 1 336 ? -32.208 -28.587 -9.449 1.00 31.16 ? 363 GLU A O 1 ATOM 2660 C CB . GLU A 1 336 ? -33.036 -31.584 -10.490 1.00 24.74 ? 363 GLU A CB 1 ATOM 2661 C CG . GLU A 1 336 ? -32.065 -30.999 -11.515 1.00 29.95 ? 363 GLU A CG 1 ATOM 2662 C CD . GLU A 1 336 ? -32.288 -31.505 -12.927 1.00 40.34 ? 363 GLU A CD 1 ATOM 2663 O OE1 . GLU A 1 336 ? -32.850 -32.613 -13.088 1.00 43.73 ? 363 GLU A OE1 1 ATOM 2664 O OE2 . GLU A 1 336 ? -31.899 -30.784 -13.876 1.00 33.85 1 363 GLU A OE2 1 ATOM 2665 N N . HIS A 1 337 ? -34.428 -28.911 -9.593 1.00 29.77 ? 364 HIS A N 1 ATOM 2666 C CA . HIS A 1 337 ? -34.697 -27.530 -9.988 1.00 25.10 ? 364 HIS A CA 1 ATOM 2667 C C . HIS A 1 337 ? -35.087 -26.627 -8.820 1.00 25.27 ? 364 HIS A C 1 ATOM 2668 O O . HIS A 1 337 ? -35.305 -25.431 -9.003 1.00 25.25 ? 364 HIS A O 1 ATOM 2669 C CB . HIS A 1 337 ? -35.798 -27.476 -11.046 1.00 23.60 ? 364 HIS A CB 1 ATOM 2670 C CG . HIS A 1 337 ? -35.700 -28.547 -12.086 1.00 29.17 ? 364 HIS A CG 1 ATOM 2671 N ND1 . HIS A 1 337 ? -36.074 -29.853 -11.847 1.00 32.92 ? 364 HIS A ND1 1 ATOM 2672 C CD2 . HIS A 1 337 ? -35.290 -28.503 -13.375 1.00 30.80 ? 364 HIS A CD2 1 ATOM 2673 C CE1 . HIS A 1 337 ? -35.892 -30.568 -12.943 1.00 37.60 ? 364 HIS A CE1 1 ATOM 2674 N NE2 . HIS A 1 337 ? -35.417 -29.773 -13.885 1.00 37.11 ? 364 HIS A NE2 1 ATOM 2675 N N . GLN A 1 338 ? -35.164 -27.195 -7.623 1.00 24.42 ? 365 GLN A N 1 ATOM 2676 C CA . GLN A 1 338 ? -35.701 -26.476 -6.473 1.00 20.74 ? 365 GLN A CA 1 ATOM 2677 C C . GLN A 1 338 ? -34.650 -25.585 -5.839 1.00 19.59 ? 365 GLN A C 1 ATOM 2678 O O . GLN A 1 338 ? -34.395 -25.668 -4.644 1.00 19.61 ? 365 GLN A O 1 ATOM 2679 C CB . GLN A 1 338 ? -36.260 -27.457 -5.442 1.00 22.77 ? 365 GLN A CB 1 ATOM 2680 C CG . GLN A 1 338 ? -37.603 -28.060 -5.822 1.00 23.49 ? 365 GLN A CG 1 ATOM 2681 C CD . GLN A 1 338 ? -37.605 -28.643 -7.224 1.00 29.75 ? 365 GLN A CD 1 ATOM 2682 O OE1 . GLN A 1 338 ? -36.789 -29.509 -7.553 1.00 25.19 ? 365 GLN A OE1 1 ATOM 2683 N NE2 . GLN A 1 338 ? -38.504 -28.145 -8.069 1.00 31.46 ? 365 GLN A NE2 1 ATOM 2684 N N . VAL A 1 339 ? -34.052 -24.727 -6.657 1.00 23.61 ? 366 VAL A N 1 ATOM 2685 C CA . VAL A 1 339 ? -32.970 -23.843 -6.236 1.00 25.36 ? 366 VAL A CA 1 ATOM 2686 C C . VAL A 1 339 ? -33.305 -23.043 -4.984 1.00 28.76 ? 366 VAL A C 1 ATOM 2687 O O . VAL A 1 339 ? -32.465 -22.892 -4.092 1.00 27.38 ? 366 VAL A O 1 ATOM 2688 C CB . VAL A 1 339 ? -32.621 -22.848 -7.355 1.00 27.30 ? 366 VAL A CB 1 ATOM 2689 C CG1 . VAL A 1 339 ? -31.500 -21.912 -6.918 1.00 27.73 ? 366 VAL A CG1 1 ATOM 2690 C CG2 . VAL A 1 339 ? -32.254 -23.600 -8.627 1.00 32.69 ? 366 VAL A CG2 1 ATOM 2691 N N . ASN A 1 340 ? -34.538 -22.545 -4.917 1.00 25.66 ? 367 ASN A N 1 ATOM 2692 C CA . ASN A 1 340 ? -34.933 -21.626 -3.854 1.00 20.30 ? 367 ASN A CA 1 ATOM 2693 C C . ASN A 1 340 ? -35.521 -22.288 -2.618 1.00 16.94 ? 367 ASN A C 1 ATOM 2694 O O . ASN A 1 340 ? -36.010 -21.601 -1.729 1.00 14.05 ? 367 ASN A O 1 ATOM 2695 C CB . ASN A 1 340 ? -35.905 -20.582 -4.390 1.00 21.51 ? 367 ASN A CB 1 ATOM 2696 C CG . ASN A 1 340 ? -35.320 -19.781 -5.521 1.00 29.91 ? 367 ASN A CG 1 ATOM 2697 O OD1 . ASN A 1 340 ? -34.585 -18.818 -5.297 1.00 31.49 ? 367 ASN A OD1 1 ATOM 2698 N ND2 . ASN A 1 340 ? -35.639 -20.172 -6.750 1.00 33.51 ? 367 ASN A ND2 1 ATOM 2699 N N . LEU A 1 341 ? -35.473 -23.616 -2.572 1.00 16.82 ? 368 LEU A N 1 ATOM 2700 C CA . LEU A 1 341 ? -35.940 -24.371 -1.414 1.00 14.02 ? 368 LEU A CA 1 ATOM 2701 C C . LEU A 1 341 ? -35.212 -23.911 -0.153 1.00 14.02 ? 368 LEU A C 1 ATOM 2702 O O . LEU A 1 341 ? -34.037 -23.564 -0.207 1.00 18.72 ? 368 LEU A O 1 ATOM 2703 C CB . LEU A 1 341 ? -35.733 -25.864 -1.655 1.00 11.76 ? 368 LEU A CB 1 ATOM 2704 C CG . LEU A 1 341 ? -36.269 -26.903 -0.677 1.00 9.84 ? 368 LEU A CG 1 ATOM 2705 C CD1 . LEU A 1 341 ? -37.587 -26.481 -0.075 1.00 10.63 ? 368 LEU A CD1 1 ATOM 2706 C CD2 . LEU A 1 341 ? -36.433 -28.212 -1.421 1.00 14.06 ? 368 LEU A CD2 1 ATOM 2707 N N . LEU A 1 342 ? -35.915 -23.894 0.973 1.00 12.19 ? 369 LEU A N 1 ATOM 2708 C CA . LEU A 1 342 ? -35.393 -23.309 2.203 1.00 10.09 ? 369 LEU A CA 1 ATOM 2709 C C . LEU A 1 342 ? -35.499 -24.263 3.391 1.00 12.18 ? 369 LEU A C 1 ATOM 2710 O O . LEU A 1 342 ? -34.798 -24.097 4.386 1.00 11.95 ? 369 LEU A O 1 ATOM 2711 C CB . LEU A 1 342 ? -36.167 -22.034 2.535 1.00 9.55 ? 369 LEU A CB 1 ATOM 2712 C CG . LEU A 1 342 ? -35.540 -20.668 2.278 1.00 7.95 ? 369 LEU A CG 1 ATOM 2713 C CD1 . LEU A 1 342 ? -34.826 -20.652 0.955 1.00 8.41 ? 369 LEU A CD1 1 ATOM 2714 C CD2 . LEU A 1 342 ? -36.607 -19.584 2.317 1.00 8.11 ? 369 LEU A CD2 1 ATOM 2715 N N . SER A 1 343 ? -36.387 -25.249 3.298 1.00 13.47 ? 370 SER A N 1 ATOM 2716 C CA . SER A 1 343 ? -36.671 -26.114 4.437 1.00 11.78 ? 370 SER A CA 1 ATOM 2717 C C . SER A 1 343 ? -37.302 -27.442 4.044 1.00 10.96 ? 370 SER A C 1 ATOM 2718 O O . SER A 1 343 ? -38.523 -27.573 4.050 1.00 12.39 ? 370 SER A O 1 ATOM 2719 C CB . SER A 1 343 ? -37.588 -25.393 5.433 1.00 13.40 ? 370 SER A CB 1 ATOM 2720 O OG . SER A 1 343 ? -38.071 -26.283 6.434 1.00 11.78 ? 370 SER A OG 1 ATOM 2721 N N . LEU A 1 344 ? -36.469 -28.422 3.705 1.00 9.12 ? 371 LEU A N 1 ATOM 2722 C CA . LEU A 1 344 ? -36.949 -29.780 3.512 1.00 8.37 ? 371 LEU A CA 1 ATOM 2723 C C . LEU A 1 344 ? -37.149 -30.395 4.882 1.00 7.23 ? 371 LEU A C 1 ATOM 2724 O O . LEU A 1 344 ? -36.464 -30.036 5.829 1.00 8.37 ? 371 LEU A O 1 ATOM 2725 C CB . LEU A 1 344 ? -35.966 -30.606 2.685 1.00 7.88 ? 371 LEU A CB 1 ATOM 2726 C CG . LEU A 1 344 ? -36.344 -32.060 2.377 1.00 9.33 ? 371 LEU A CG 1 ATOM 2727 C CD1 . LEU A 1 344 ? -37.791 -32.190 1.940 1.00 7.72 ? 371 LEU A CD1 1 ATOM 2728 C CD2 . LEU A 1 344 ? -35.431 -32.634 1.306 1.00 9.05 ? 371 LEU A CD2 1 ATOM 2729 N N . ASP A 1 345 ? -38.107 -31.302 4.991 1.00 7.90 ? 372 ASP A N 1 ATOM 2730 C CA . ASP A 1 345 ? -38.426 -31.917 6.266 1.00 8.84 ? 372 ASP A CA 1 ATOM 2731 C C . ASP A 1 345 ? -38.911 -33.340 6.043 1.00 9.02 ? 372 ASP A C 1 ATOM 2732 O O . ASP A 1 345 ? -40.085 -33.576 5.757 1.00 9.63 ? 372 ASP A O 1 ATOM 2733 C CB . ASP A 1 345 ? -39.476 -31.090 7.011 1.00 8.61 ? 372 ASP A CB 1 ATOM 2734 C CG . ASP A 1 345 ? -40.052 -31.817 8.209 1.00 10.15 ? 372 ASP A CG 1 ATOM 2735 O OD1 . ASP A 1 345 ? -39.312 -32.584 8.860 1.00 9.65 ? 372 ASP A OD1 1 ATOM 2736 O OD2 . ASP A 1 345 ? -41.253 -31.623 8.495 1.00 11.35 1 372 ASP A OD2 1 ATOM 2737 N N . LEU A 1 346 ? -37.985 -34.282 6.173 1.00 8.62 ? 373 LEU A N 1 ATOM 2738 C CA . LEU A 1 346 ? -38.278 -35.686 5.959 1.00 7.81 ? 373 LEU A CA 1 ATOM 2739 C C . LEU A 1 346 ? -38.344 -36.427 7.281 1.00 8.43 ? 373 LEU A C 1 ATOM 2740 O O . LEU A 1 346 ? -38.057 -37.618 7.345 1.00 10.23 ? 373 LEU A O 1 ATOM 2741 C CB . LEU A 1 346 ? -37.211 -36.307 5.067 1.00 6.26 ? 373 LEU A CB 1 ATOM 2742 C CG . LEU A 1 346 ? -37.189 -35.797 3.632 1.00 7.64 ? 373 LEU A CG 1 ATOM 2743 C CD1 . LEU A 1 346 ? -35.869 -36.126 2.978 1.00 7.09 ? 373 LEU A CD1 1 ATOM 2744 C CD2 . LEU A 1 346 ? -38.331 -36.416 2.860 1.00 9.91 ? 373 LEU A CD2 1 ATOM 2745 N N . SER A 1 347 ? -38.721 -35.719 8.337 1.00 7.35 ? 374 SER A N 1 ATOM 2746 C CA . SER A 1 347 ? -38.847 -36.337 9.648 1.00 11.01 ? 374 SER A CA 1 ATOM 2747 C C . SER A 1 347 ? -39.864 -37.487 9.667 1.00 16.19 ? 374 SER A C 1 ATOM 2748 O O . SER A 1 347 ? -40.903 -37.427 9.008 1.00 13.30 ? 374 SER A O 1 ATOM 2749 C CB . SER A 1 347 ? -39.203 -35.285 10.697 1.00 12.90 ? 374 SER A CB 1 ATOM 2750 O OG . SER A 1 347 ? -40.100 -34.329 10.163 1.00 12.63 ? 374 SER A OG 1 ATOM 2751 N N . ASN A 1 348 ? -39.537 -38.533 10.422 1.00 18.26 ? 375 ASN A N 1 ATOM 2752 C CA . ASN A 1 348 ? -40.385 -39.720 10.563 1.00 15.32 ? 375 ASN A CA 1 ATOM 2753 C C . ASN A 1 348 ? -40.702 -40.441 9.259 1.00 15.63 ? 375 ASN A C 1 ATOM 2754 O O . ASN A 1 348 ? -41.809 -40.349 8.737 1.00 17.81 ? 375 ASN A O 1 ATOM 2755 C CB . ASN A 1 348 ? -41.673 -39.391 11.312 1.00 14.14 ? 375 ASN A CB 1 ATOM 2756 C CG . ASN A 1 348 ? -41.409 -38.780 12.661 1.00 18.70 ? 375 ASN A CG 1 ATOM 2757 O OD1 . ASN A 1 348 ? -41.351 -37.556 12.798 1.00 22.33 ? 375 ASN A OD1 1 ATOM 2758 N ND2 . ASN A 1 348 ? -41.236 -39.627 13.671 1.00 16.32 ? 375 ASN A ND2 1 ATOM 2759 N N . ASN A 1 349 ? -39.715 -41.150 8.731 1.00 17.68 ? 376 ASN A N 1 ATOM 2760 C CA . ASN A 1 349 ? -39.934 -42.049 7.611 1.00 18.62 ? 376 ASN A CA 1 ATOM 2761 C C . ASN A 1 349 ? -39.131 -43.317 7.846 1.00 21.15 ? 376 ASN A C 1 ATOM 2762 O O . ASN A 1 349 ? -38.639 -43.558 8.951 1.00 19.23 ? 376 ASN A O 1 ATOM 2763 C CB . ASN A 1 349 ? -39.520 -41.398 6.290 1.00 15.80 ? 376 ASN A CB 1 ATOM 2764 C CG . ASN A 1 349 ? -40.439 -40.263 5.878 1.00 15.97 ? 376 ASN A CG 1 ATOM 2765 O OD1 . ASN A 1 349 ? -41.193 -40.385 4.916 1.00 16.55 ? 376 ASN A OD1 1 ATOM 2766 N ND2 . ASN A 1 349 ? -40.375 -39.150 6.599 1.00 13.91 ? 376 ASN A ND2 1 ATOM 2767 N N . ARG A 1 350 ? -39.005 -44.130 6.808 1.00 21.61 ? 377 ARG A N 1 ATOM 2768 C CA . ARG A 1 350 ? -38.139 -45.294 6.869 1.00 25.69 ? 377 ARG A CA 1 ATOM 2769 C C . ARG A 1 350 ? -36.936 -45.033 5.963 1.00 23.34 ? 377 ARG A C 1 ATOM 2770 O O . ARG A 1 350 ? -36.392 -45.949 5.340 1.00 22.39 ? 377 ARG A O 1 ATOM 2771 C CB . ARG A 1 350 ? -38.892 -46.553 6.433 1.00 27.00 ? 377 ARG A CB 1 ATOM 2772 C CG . ARG A 1 350 ? -40.342 -46.610 6.896 1.00 25.51 ? 377 ARG A CG 1 ATOM 2773 C CD . ARG A 1 350 ? -40.463 -46.671 8.411 1.00 32.75 ? 377 ARG A CD 1 ATOM 2774 N NE . ARG A 1 350 ? -41.860 -46.651 8.853 1.00 46.47 ? 377 ARG A NE 1 ATOM 2775 C CZ . ARG A 1 350 ? -42.574 -47.730 9.172 1.00 45.25 ? 377 ARG A CZ 1 ATOM 2776 N NH1 . ARG A 1 350 ? -43.835 -47.597 9.563 1.00 39.05 1 377 ARG A NH1 1 ATOM 2777 N NH2 . ARG A 1 350 ? -42.033 -48.942 9.107 1.00 39.18 ? 377 ARG A NH2 1 ATOM 2778 N N . LEU A 1 351 ? -36.539 -43.765 5.892 1.00 18.30 ? 378 LEU A N 1 ATOM 2779 C CA . LEU A 1 351 ? -35.420 -43.355 5.059 1.00 16.82 ? 378 LEU A CA 1 ATOM 2780 C C . LEU A 1 351 ? -34.155 -44.073 5.474 1.00 16.22 ? 378 LEU A C 1 ATOM 2781 O O . LEU A 1 351 ? -33.718 -43.947 6.611 1.00 18.49 ? 378 LEU A O 1 ATOM 2782 C CB . LEU A 1 351 ? -35.201 -41.850 5.157 1.00 14.31 ? 378 LEU A CB 1 ATOM 2783 C CG . LEU A 1 351 ? -36.106 -40.968 4.306 1.00 12.43 ? 378 LEU A CG 1 ATOM 2784 C CD1 . LEU A 1 351 ? -35.799 -39.525 4.593 1.00 11.22 ? 378 LEU A CD1 1 ATOM 2785 C CD2 . LEU A 1 351 ? -35.899 -41.262 2.838 1.00 13.05 ? 378 LEU A CD2 1 ATOM 2786 N N . THR A 1 352 ? -33.573 -44.828 4.549 1.00 20.46 ? 379 THR A N 1 ATOM 2787 C CA . THR A 1 352 ? -32.343 -45.562 4.824 1.00 19.76 ? 379 THR A CA 1 ATOM 2788 C C . THR A 1 352 ? -31.155 -45.006 4.041 1.00 20.56 ? 379 THR A C 1 ATOM 2789 O O . THR A 1 352 ? -30.003 -45.238 4.406 1.00 23.94 ? 379 THR A O 1 ATOM 2790 C CB . THR A 1 352 ? -32.504 -47.066 4.538 1.00 19.03 ? 379 THR A CB 1 ATOM 2791 O OG1 . THR A 1 352 ? -32.903 -47.262 3.175 1.00 17.46 ? 379 THR A OG1 1 ATOM 2792 C CG2 . THR A 1 352 ? -33.550 -47.657 5.461 1.00 17.48 ? 379 THR A CG2 1 ATOM 2793 N N . HIS A 1 353 ? -31.438 -44.265 2.974 1.00 18.81 ? 380 HIS A N 1 ATOM 2794 C CA . HIS A 1 353 ? -30.387 -43.622 2.195 1.00 19.15 ? 380 HIS A CA 1 ATOM 2795 C C . HIS A 1 353 ? -30.925 -42.511 1.300 1.00 21.24 ? 380 HIS A C 1 ATOM 2796 O O . HIS A 1 353 ? -32.020 -42.609 0.758 1.00 25.53 ? 380 HIS A O 1 ATOM 2797 C CB . HIS A 1 353 ? -29.643 -44.654 1.352 1.00 23.85 ? 380 HIS A CB 1 ATOM 2798 C CG . HIS A 1 353 ? -30.530 -45.438 0.436 1.00 31.48 ? 380 HIS A CG 1 ATOM 2799 N ND1 . HIS A 1 353 ? -30.763 -45.067 -0.872 1.00 39.06 ? 380 HIS A ND1 1 ATOM 2800 C CD2 . HIS A 1 353 ? -31.238 -46.575 0.636 1.00 27.27 ? 380 HIS A CD2 1 ATOM 2801 C CE1 . HIS A 1 353 ? -31.574 -45.943 -1.438 1.00 41.32 ? 380 HIS A CE1 1 ATOM 2802 N NE2 . HIS A 1 353 ? -31.877 -46.869 -0.545 1.00 37.43 ? 380 HIS A NE2 1 ATOM 2803 N N . LEU A 1 354 ? -30.140 -41.455 1.144 1.00 20.12 ? 381 LEU A N 1 ATOM 2804 C CA . LEU A 1 354 ? -30.512 -40.340 0.289 1.00 18.71 ? 381 LEU A CA 1 ATOM 2805 C C . LEU A 1 354 ? -29.431 -40.139 -0.751 1.00 23.14 ? 381 LEU A C 1 ATOM 2806 O O . LEU A 1 354 ? -28.385 -39.578 -0.432 1.00 24.53 ? 381 LEU A O 1 ATOM 2807 C CB . LEU A 1 354 ? -30.607 -39.060 1.112 1.00 20.47 ? 381 LEU A CB 1 ATOM 2808 C CG . LEU A 1 354 ? -31.329 -39.109 2.453 1.00 20.07 ? 381 LEU A CG 1 ATOM 2809 C CD1 . LEU A 1 354 ? -30.876 -37.948 3.323 1.00 13.31 ? 381 LEU A CD1 1 ATOM 2810 C CD2 . LEU A 1 354 ? -32.829 -39.067 2.234 1.00 18.71 ? 381 LEU A CD2 1 ATOM 2811 N N . PRO A 1 355 ? -29.675 -40.601 -1.989 1.00 25.82 ? 382 PRO A N 1 ATOM 2812 C CA . PRO A 1 355 ? -28.806 -40.429 -3.156 1.00 31.38 ? 382 PRO A CA 1 ATOM 2813 C C . PRO A 1 355 ? -27.943 -39.176 -3.063 1.00 29.88 ? 382 PRO A C 1 ATOM 2814 O O . PRO A 1 355 ? -28.488 -38.076 -2.953 1.00 26.35 ? 382 PRO A O 1 ATOM 2815 C CB . PRO A 1 355 ? -29.814 -40.294 -4.296 1.00 30.70 ? 382 PRO A CB 1 ATOM 2816 C CG . PRO A 1 355 ? -31.027 -41.101 -3.826 1.00 29.41 ? 382 PRO A CG 1 ATOM 2817 C CD . PRO A 1 355 ? -30.863 -41.390 -2.343 1.00 25.75 ? 382 PRO A CD 1 ATOM 2818 N N . ASP A 1 356 ? -26.622 -39.355 -3.093 1.00 28.90 ? 383 ASP A N 1 ATOM 2819 C CA . ASP A 1 356 ? -25.657 -38.294 -2.779 1.00 28.43 ? 383 ASP A CA 1 ATOM 2820 C C . ASP A 1 356 ? -25.843 -36.985 -3.544 1.00 31.72 ? 383 ASP A C 1 ATOM 2821 O O . ASP A 1 356 ? -25.291 -35.952 -3.160 1.00 29.72 ? 383 ASP A O 1 ATOM 2822 C CB . ASP A 1 356 ? -24.227 -38.799 -2.979 1.00 27.59 ? 383 ASP A CB 1 ATOM 2823 C CG . ASP A 1 356 ? -23.777 -39.722 -1.870 1.00 34.59 ? 383 ASP A CG 1 ATOM 2824 O OD1 . ASP A 1 356 ? -24.083 -39.430 -0.694 1.00 34.25 ? 383 ASP A OD1 1 ATOM 2825 O OD2 . ASP A 1 356 ? -23.119 -40.740 -2.174 1.00 38.77 1 383 ASP A OD2 1 ATOM 2826 N N . SER A 1 357 ? -26.618 -37.038 -4.622 1.00 34.37 ? 384 SER A N 1 ATOM 2827 C CA . SER A 1 357 ? -26.862 -35.872 -5.459 1.00 26.62 ? 384 SER A CA 1 ATOM 2828 C C . SER A 1 357 ? -28.222 -35.258 -5.182 1.00 26.19 ? 384 SER A C 1 ATOM 2829 O O . SER A 1 357 ? -28.700 -34.453 -5.973 1.00 25.99 ? 384 SER A O 1 ATOM 2830 C CB . SER A 1 357 ? -26.796 -36.270 -6.930 1.00 26.97 ? 384 SER A CB 1 ATOM 2831 O OG . SER A 1 357 ? -27.751 -37.282 -7.216 1.00 31.20 ? 384 SER A OG 1 ATOM 2832 N N . LEU A 1 358 ? -28.851 -35.645 -4.073 1.00 28.75 ? 385 LEU A N 1 ATOM 2833 C CA . LEU A 1 358 ? -30.211 -35.188 -3.778 1.00 29.77 ? 385 LEU A CA 1 ATOM 2834 C C . LEU A 1 358 ? -30.247 -33.686 -3.560 1.00 23.97 ? 385 LEU A C 1 ATOM 2835 O O . LEU A 1 358 ? -31.019 -32.970 -4.200 1.00 22.09 ? 385 LEU A O 1 ATOM 2836 C CB . LEU A 1 358 ? -30.795 -35.913 -2.563 1.00 25.62 ? 385 LEU A CB 1 ATOM 2837 C CG . LEU A 1 358 ? -32.237 -35.546 -2.198 1.00 20.28 ? 385 LEU A CG 1 ATOM 2838 C CD1 . LEU A 1 358 ? -33.165 -35.721 -3.383 1.00 18.56 ? 385 LEU A CD1 1 ATOM 2839 C CD2 . LEU A 1 358 ? -32.718 -36.382 -1.031 1.00 20.67 ? 385 LEU A CD2 1 ATOM 2840 N N . PHE A 1 359 ? -29.396 -33.211 -2.662 1.00 20.26 ? 386 PHE A N 1 ATOM 2841 C CA . PHE A 1 359 ? -29.290 -31.786 -2.418 1.00 25.30 ? 386 PHE A CA 1 ATOM 2842 C C . PHE A 1 359 ? -28.189 -31.185 -3.283 1.00 27.24 ? 386 PHE A C 1 ATOM 2843 O O . PHE A 1 359 ? -27.481 -30.269 -2.860 1.00 29.17 ? 386 PHE A O 1 ATOM 2844 C CB . PHE A 1 359 ? -29.011 -31.521 -0.941 1.00 27.13 ? 386 PHE A CB 1 ATOM 2845 C CG . PHE A 1 359 ? -29.817 -32.380 -0.013 1.00 25.43 ? 386 PHE A CG 1 ATOM 2846 C CD1 . PHE A 1 359 ? -31.176 -32.190 0.121 1.00 22.15 ? 386 PHE A CD1 1 ATOM 2847 C CD2 . PHE A 1 359 ? -29.211 -33.377 0.729 1.00 26.37 ? 386 PHE A CD2 1 ATOM 2848 C CE1 . PHE A 1 359 ? -31.914 -32.980 0.977 1.00 21.53 ? 386 PHE A CE1 1 ATOM 2849 C CE2 . PHE A 1 359 ? -29.948 -34.169 1.584 1.00 22.19 ? 386 PHE A CE2 1 ATOM 2850 C CZ . PHE A 1 359 ? -31.298 -33.970 1.708 1.00 17.27 ? 386 PHE A CZ 1 ATOM 2851 N N . ALA A 1 360 ? -28.049 -31.712 -4.497 1.00 24.23 ? 387 ALA A N 1 ATOM 2852 C CA . ALA A 1 360 ? -27.053 -31.220 -5.439 1.00 22.95 ? 387 ALA A CA 1 ATOM 2853 C C . ALA A 1 360 ? -27.282 -29.753 -5.756 1.00 23.41 ? 387 ALA A C 1 ATOM 2854 O O . ALA A 1 360 ? -26.385 -28.927 -5.605 1.00 23.34 ? 387 ALA A O 1 ATOM 2855 C CB . ALA A 1 360 ? -27.074 -32.041 -6.719 1.00 21.36 ? 387 ALA A CB 1 ATOM 2856 N N . HIS A 1 361 ? -28.496 -29.428 -6.183 1.00 26.76 ? 388 HIS A N 1 ATOM 2857 C CA . HIS A 1 361 ? -28.782 -28.084 -6.658 1.00 26.90 ? 388 HIS A CA 1 ATOM 2858 C C . HIS A 1 361 ? -29.495 -27.219 -5.607 1.00 23.33 ? 388 HIS A C 1 ATOM 2859 O O . HIS A 1 361 ? -29.567 -26.001 -5.762 1.00 22.74 ? 388 HIS A O 1 ATOM 2860 C CB . HIS A 1 361 ? -29.583 -28.131 -7.970 1.00 24.67 ? 388 HIS A CB 1 ATOM 2861 C CG . HIS A 1 361 ? -28.984 -29.014 -9.030 1.00 26.54 ? 388 HIS A CG 1 ATOM 2862 N ND1 . HIS A 1 361 ? -28.920 -30.387 -8.913 1.00 26.01 ? 388 HIS A ND1 1 ATOM 2863 C CD2 . HIS A 1 361 ? -28.444 -28.717 -10.237 1.00 29.20 ? 388 HIS A CD2 1 ATOM 2864 C CE1 . HIS A 1 361 ? -28.358 -30.897 -9.995 1.00 23.80 ? 388 HIS A CE1 1 ATOM 2865 N NE2 . HIS A 1 361 ? -28.060 -29.904 -10.815 1.00 28.44 ? 388 HIS A NE2 1 ATOM 2866 N N . THR A 1 362 ? -29.997 -27.832 -4.534 1.00 18.81 ? 389 THR A N 1 ATOM 2867 C CA . THR A 1 362 ? -30.742 -27.090 -3.508 1.00 21.22 ? 389 THR A CA 1 ATOM 2868 C C . THR A 1 362 ? -29.857 -26.088 -2.759 1.00 23.45 ? 389 THR A C 1 ATOM 2869 O O . THR A 1 362 ? -29.743 -26.129 -1.533 1.00 22.33 ? 389 THR A O 1 ATOM 2870 C CB . THR A 1 362 ? -31.442 -28.030 -2.490 1.00 20.30 ? 389 THR A CB 1 ATOM 2871 O OG1 . THR A 1 362 ? -30.465 -28.753 -1.729 1.00 19.82 ? 389 THR A OG1 1 ATOM 2872 C CG2 . THR A 1 362 ? -32.352 -29.012 -3.204 1.00 19.00 ? 389 THR A CG2 1 ATOM 2873 N N . THR A 1 363 ? -29.270 -25.166 -3.514 1.00 26.08 ? 390 THR A N 1 ATOM 2874 C CA . THR A 1 363 ? -28.173 -24.320 -3.048 1.00 25.98 ? 390 THR A CA 1 ATOM 2875 C C . THR A 1 363 ? -28.531 -23.404 -1.886 1.00 25.85 ? 390 THR A C 1 ATOM 2876 O O . THR A 1 363 ? -27.641 -22.929 -1.181 1.00 22.69 ? 390 THR A O 1 ATOM 2877 C CB . THR A 1 363 ? -27.643 -23.431 -4.195 1.00 30.05 ? 390 THR A CB 1 ATOM 2878 O OG1 . THR A 1 363 ? -27.980 -24.017 -5.462 1.00 28.41 ? 390 THR A OG1 1 ATOM 2879 C CG2 . THR A 1 363 ? -26.141 -23.268 -4.086 1.00 37.33 ? 390 THR A CG2 1 ATOM 2880 N N . ASN A 1 364 ? -29.825 -23.148 -1.698 1.00 26.99 ? 391 ASN A N 1 ATOM 2881 C CA . ASN A 1 364 ? -30.282 -22.166 -0.712 1.00 26.00 ? 391 ASN A CA 1 ATOM 2882 C C . ASN A 1 364 ? -30.843 -22.785 0.560 1.00 20.11 ? 391 ASN A C 1 ATOM 2883 O O . ASN A 1 364 ? -31.175 -22.074 1.519 1.00 12.84 ? 391 ASN A O 1 ATOM 2884 C CB . ASN A 1 364 ? -31.309 -21.216 -1.331 1.00 24.82 ? 391 ASN A CB 1 ATOM 2885 C CG . ASN A 1 364 ? -30.666 -20.006 -1.974 1.00 33.58 ? 391 ASN A CG 1 ATOM 2886 O OD1 . ASN A 1 364 ? -30.662 -18.914 -1.402 1.00 34.25 ? 391 ASN A OD1 1 ATOM 2887 N ND2 . ASN A 1 364 ? -30.101 -20.195 -3.159 1.00 39.19 ? 391 ASN A ND2 1 ATOM 2888 N N . LEU A 1 365 ? -30.932 -24.113 0.546 1.00 18.70 ? 392 LEU A N 1 ATOM 2889 C CA . LEU A 1 365 ? -31.438 -24.895 1.670 1.00 15.24 ? 392 LEU A CA 1 ATOM 2890 C C . LEU A 1 365 ? -30.885 -24.399 3.007 1.00 15.23 ? 392 LEU A C 1 ATOM 2891 O O . LEU A 1 365 ? -29.678 -24.234 3.164 1.00 23.40 ? 392 LEU A O 1 ATOM 2892 C CB . LEU A 1 365 ? -31.100 -26.373 1.460 1.00 13.52 ? 392 LEU A CB 1 ATOM 2893 C CG . LEU A 1 365 ? -31.707 -27.370 2.438 1.00 11.47 ? 392 LEU A CG 1 ATOM 2894 C CD1 . LEU A 1 365 ? -33.169 -27.074 2.621 1.00 12.17 ? 392 LEU A CD1 1 ATOM 2895 C CD2 . LEU A 1 365 ? -31.524 -28.776 1.917 1.00 14.64 ? 392 LEU A CD2 1 ATOM 2896 N N . THR A 1 366 ? -31.775 -24.140 3.957 1.00 11.86 ? 393 THR A N 1 ATOM 2897 C CA . THR A 1 366 ? -31.376 -23.601 5.248 1.00 11.18 ? 393 THR A CA 1 ATOM 2898 C C . THR A 1 366 ? -31.609 -24.591 6.376 1.00 12.42 ? 393 THR A C 1 ATOM 2899 O O . THR A 1 366 ? -30.672 -25.011 7.043 1.00 16.66 ? 393 THR A O 1 ATOM 2900 C CB . THR A 1 366 ? -32.119 -22.305 5.551 1.00 12.56 ? 393 THR A CB 1 ATOM 2901 O OG1 . THR A 1 366 ? -31.694 -21.301 4.620 1.00 14.06 ? 393 THR A OG1 1 ATOM 2902 C CG2 . THR A 1 366 ? -31.838 -21.844 6.969 1.00 12.55 ? 393 THR A CG2 1 ATOM 2903 N N . ASP A 1 367 ? -32.864 -24.953 6.599 1.00 12.01 ? 394 ASP A N 1 ATOM 2904 C CA . ASP A 1 367 ? -33.184 -25.951 7.608 1.00 12.87 ? 394 ASP A CA 1 ATOM 2905 C C . ASP A 1 367 ? -33.452 -27.300 6.960 1.00 11.92 ? 394 ASP A C 1 ATOM 2906 O O . ASP A 1 367 ? -34.354 -27.423 6.142 1.00 12.62 ? 394 ASP A O 1 ATOM 2907 C CB . ASP A 1 367 ? -34.412 -25.534 8.418 1.00 13.70 ? 394 ASP A CB 1 ATOM 2908 C CG . ASP A 1 367 ? -34.142 -24.359 9.339 1.00 13.47 ? 394 ASP A CG 1 ATOM 2909 O OD1 . ASP A 1 367 ? -33.987 -23.223 8.837 1.00 16.77 ? 394 ASP A OD1 1 ATOM 2910 O OD2 . ASP A 1 367 ? -34.112 -24.572 10.569 1.00 9.93 1 394 ASP A OD2 1 ATOM 2911 N N . LEU A 1 368 ? -32.669 -28.309 7.324 1.00 11.76 ? 395 LEU A N 1 ATOM 2912 C CA . LEU A 1 368 ? -32.967 -29.676 6.921 1.00 8.61 ? 395 LEU A CA 1 ATOM 2913 C C . LEU A 1 368 ? -33.282 -30.517 8.148 1.00 9.04 ? 395 LEU A C 1 ATOM 2914 O O . LEU A 1 368 ? -32.620 -30.407 9.173 1.00 11.32 ? 395 LEU A O 1 ATOM 2915 C CB . LEU A 1 368 ? -31.815 -30.295 6.131 1.00 9.11 ? 395 LEU A CB 1 ATOM 2916 C CG . LEU A 1 368 ? -32.065 -31.722 5.633 1.00 11.10 ? 395 LEU A CG 1 ATOM 2917 C CD1 . LEU A 1 368 ? -33.407 -31.824 4.933 1.00 11.15 ? 395 LEU A CD1 1 ATOM 2918 C CD2 . LEU A 1 368 ? -30.967 -32.184 4.697 1.00 13.78 ? 395 LEU A CD2 1 ATOM 2919 N N . ARG A 1 369 ? -34.317 -31.340 8.042 1.00 9.97 ? 396 ARG A N 1 ATOM 2920 C CA . ARG A 1 369 ? -34.718 -32.223 9.127 1.00 10.71 ? 396 ARG A CA 1 ATOM 2921 C C . ARG A 1 369 ? -34.821 -33.651 8.603 1.00 8.94 ? 396 ARG A C 1 ATOM 2922 O O . ARG A 1 369 ? -35.414 -33.893 7.557 1.00 9.02 ? 396 ARG A O 1 ATOM 2923 C CB . ARG A 1 369 ? -36.044 -31.759 9.733 1.00 10.29 ? 396 ARG A CB 1 ATOM 2924 C CG . ARG A 1 369 ? -36.019 -30.317 10.209 1.00 11.10 ? 396 ARG A CG 1 ATOM 2925 C CD . ARG A 1 369 ? -37.295 -29.942 10.936 1.00 16.47 ? 396 ARG A CD 1 ATOM 2926 N NE . ARG A 1 369 ? -37.520 -30.782 12.112 1.00 30.39 ? 396 ARG A NE 1 ATOM 2927 C CZ . ARG A 1 369 ? -36.987 -30.560 13.313 1.00 28.72 ? 396 ARG A CZ 1 ATOM 2928 N NH1 . ARG A 1 369 ? -37.256 -31.383 14.324 1.00 18.86 1 396 ARG A NH1 1 ATOM 2929 N NH2 . ARG A 1 369 ? -36.185 -29.518 13.504 1.00 23.91 ? 396 ARG A NH2 1 ATOM 2930 N N . LEU A 1 370 ? -34.221 -34.589 9.326 1.00 9.36 ? 397 LEU A N 1 ATOM 2931 C CA . LEU A 1 370 ? -34.134 -35.971 8.878 1.00 7.61 ? 397 LEU A CA 1 ATOM 2932 C C . LEU A 1 370 ? -34.333 -36.902 10.061 1.00 10.13 ? 397 LEU A C 1 ATOM 2933 O O . LEU A 1 370 ? -34.183 -38.118 9.941 1.00 10.72 ? 397 LEU A O 1 ATOM 2934 C CB . LEU A 1 370 ? -32.768 -36.230 8.251 1.00 7.28 ? 397 LEU A CB 1 ATOM 2935 C CG . LEU A 1 370 ? -32.427 -35.472 6.972 1.00 7.16 ? 397 LEU A CG 1 ATOM 2936 C CD1 . LEU A 1 370 ? -30.948 -35.175 6.877 1.00 6.35 ? 397 LEU A CD1 1 ATOM 2937 C CD2 . LEU A 1 370 ? -32.863 -36.291 5.789 1.00 11.10 ? 397 LEU A CD2 1 ATOM 2938 N N . GLU A 1 371 ? -34.674 -36.319 11.206 1.00 9.59 ? 398 GLU A N 1 ATOM 2939 C CA . GLU A 1 371 ? -34.835 -37.080 12.438 1.00 11.10 ? 398 GLU A CA 1 ATOM 2940 C C . GLU A 1 371 ? -35.912 -38.166 12.377 1.00 14.02 ? 398 GLU A C 1 ATOM 2941 O O . GLU A 1 371 ? -36.950 -38.016 11.727 1.00 11.80 ? 398 GLU A O 1 ATOM 2942 C CB . GLU A 1 371 ? -35.097 -36.149 13.623 1.00 12.22 ? 398 GLU A CB 1 ATOM 2943 C CG . GLU A 1 371 ? -36.421 -35.412 13.564 1.00 17.02 ? 398 GLU A CG 1 ATOM 2944 C CD . GLU A 1 371 ? -36.357 -34.139 12.740 1.00 14.11 ? 398 GLU A CD 1 ATOM 2945 O OE1 . GLU A 1 371 ? -35.402 -33.977 11.947 1.00 12.29 ? 398 GLU A OE1 1 ATOM 2946 O OE2 . GLU A 1 371 ? -37.266 -33.298 12.898 1.00 12.11 1 398 GLU A OE2 1 ATOM 2947 N N . ASP A 1 372 ? -35.639 -39.258 13.080 1.00 18.71 ? 399 ASP A N 1 ATOM 2948 C CA . ASP A 1 372 ? -36.505 -40.433 13.111 1.00 17.68 ? 399 ASP A CA 1 ATOM 2949 C C . ASP A 1 372 ? -36.588 -41.136 11.763 1.00 14.79 ? 399 ASP A C 1 ATOM 2950 O O . ASP A 1 372 ? -37.645 -41.245 11.144 1.00 13.93 ? 399 ASP A O 1 ATOM 2951 C CB . ASP A 1 372 ? -37.868 -40.104 13.714 1.00 15.32 ? 399 ASP A CB 1 ATOM 2952 C CG . ASP A 1 372 ? -37.757 -39.710 15.168 1.00 13.63 ? 399 ASP A CG 1 ATOM 2953 O OD1 . ASP A 1 372 ? -37.779 -40.617 16.029 1.00 11.61 ? 399 ASP A OD1 1 ATOM 2954 O OD2 . ASP A 1 372 ? -37.608 -38.500 15.444 1.00 13.03 1 399 ASP A OD2 1 ATOM 2955 N N . ASN A 1 373 ? -35.429 -41.607 11.326 1.00 13.97 ? 400 ASN A N 1 ATOM 2956 C CA . ASN A 1 373 ? -35.320 -42.440 10.149 1.00 15.42 ? 400 ASN A CA 1 ATOM 2957 C C . ASN A 1 373 ? -34.299 -43.530 10.404 1.00 13.28 ? 400 ASN A C 1 ATOM 2958 O O . ASN A 1 373 ? -33.821 -43.689 11.524 1.00 15.66 ? 400 ASN A O 1 ATOM 2959 C CB . ASN A 1 373 ? -34.924 -41.608 8.937 1.00 15.37 ? 400 ASN A CB 1 ATOM 2960 C CG . ASN A 1 373 ? -36.021 -40.670 8.500 1.00 14.35 ? 400 ASN A CG 1 ATOM 2961 O OD1 . ASN A 1 373 ? -36.860 -41.024 7.678 1.00 13.33 ? 400 ASN A OD1 1 ATOM 2962 N ND2 . ASN A 1 373 ? -36.027 -39.468 9.055 1.00 12.99 ? 400 ASN A ND2 1 ATOM 2963 N N . LEU A 1 374 ? -33.977 -44.287 9.368 1.00 12.34 ? 401 LEU A N 1 ATOM 2964 C CA . LEU A 1 374 ? -33.025 -45.371 9.503 1.00 12.36 ? 401 LEU A CA 1 ATOM 2965 C C . LEU A 1 374 ? -31.781 -45.049 8.703 1.00 10.99 ? 401 LEU A C 1 ATOM 2966 O O . LEU A 1 374 ? -31.182 -45.927 8.082 1.00 10.13 ? 401 LEU A O 1 ATOM 2967 C CB . LEU A 1 374 ? -33.645 -46.676 9.022 1.00 13.15 ? 401 LEU A CB 1 ATOM 2968 C CG . LEU A 1 374 ? -34.993 -46.974 9.667 1.00 10.63 ? 401 LEU A CG 1 ATOM 2969 C CD1 . LEU A 1 374 ? -35.492 -48.334 9.229 1.00 22.59 ? 401 LEU A CD1 1 ATOM 2970 C CD2 . LEU A 1 374 ? -34.877 -46.904 11.174 1.00 10.54 ? 401 LEU A CD2 1 ATOM 2971 N N . LEU A 1 375 ? -31.414 -43.774 8.705 1.00 9.56 ? 402 LEU A N 1 ATOM 2972 C CA . LEU A 1 375 ? -30.184 -43.347 8.069 1.00 11.99 ? 402 LEU A CA 1 ATOM 2973 C C . LEU A 1 375 ? -29.046 -43.972 8.852 1.00 15.67 ? 402 LEU A C 1 ATOM 2974 O O . LEU A 1 375 ? -29.195 -44.246 10.043 1.00 17.23 ? 402 LEU A O 1 ATOM 2975 C CB . LEU A 1 375 ? -30.065 -41.826 8.083 1.00 11.98 ? 402 LEU A CB 1 ATOM 2976 C CG . LEU A 1 375 ? -31.030 -41.018 7.216 1.00 8.13 ? 402 LEU A CG 1 ATOM 2977 C CD1 . LEU A 1 375 ? -30.640 -39.559 7.255 1.00 5.89 ? 402 LEU A CD1 1 ATOM 2978 C CD2 . LEU A 1 375 ? -31.045 -41.525 5.787 1.00 10.91 ? 402 LEU A CD2 1 ATOM 2979 N N . THR A 1 376 ? -27.914 -44.207 8.199 1.00 14.01 ? 403 THR A N 1 ATOM 2980 C CA . THR A 1 376 ? -26.850 -44.966 8.844 1.00 12.98 ? 403 THR A CA 1 ATOM 2981 C C . THR A 1 376 ? -25.468 -44.343 8.749 1.00 15.10 ? 403 THR A C 1 ATOM 2982 O O . THR A 1 376 ? -24.494 -44.927 9.212 1.00 16.13 ? 403 THR A O 1 ATOM 2983 C CB . THR A 1 376 ? -26.772 -46.376 8.283 1.00 10.48 ? 403 THR A CB 1 ATOM 2984 O OG1 . THR A 1 376 ? -26.894 -46.319 6.855 1.00 9.82 ? 403 THR A OG1 1 ATOM 2985 C CG2 . THR A 1 376 ? -27.888 -47.218 8.862 1.00 10.49 ? 403 THR A CG2 1 ATOM 2986 N N . GLY A 1 377 ? -25.370 -43.166 8.154 1.00 11.21 ? 404 GLY A N 1 ATOM 2987 C CA . GLY A 1 377 ? -24.084 -42.512 8.087 1.00 8.97 ? 404 GLY A CA 1 ATOM 2988 C C . GLY A 1 377 ? -24.097 -41.368 7.115 1.00 8.76 ? 404 GLY A C 1 ATOM 2989 O O . GLY A 1 377 ? -24.811 -41.406 6.119 1.00 9.79 ? 404 GLY A O 1 ATOM 2990 N N . ILE A 1 378 ? -23.307 -40.346 7.412 1.00 8.60 ? 405 ILE A N 1 ATOM 2991 C CA . ILE A 1 378 ? -23.193 -39.200 6.532 1.00 9.09 ? 405 ILE A CA 1 ATOM 2992 C C . ILE A 1 378 ? -22.021 -39.403 5.583 1.00 10.46 ? 405 ILE A C 1 ATOM 2993 O O . ILE A 1 378 ? -20.904 -39.655 6.011 1.00 11.21 ? 405 ILE A O 1 ATOM 2994 C CB . ILE A 1 378 ? -23.029 -37.885 7.314 1.00 8.44 ? 405 ILE A CB 1 ATOM 2995 C CG1 . ILE A 1 378 ? -24.242 -37.633 8.208 1.00 7.58 ? 405 ILE A CG1 1 ATOM 2996 C CG2 . ILE A 1 378 ? -22.880 -36.722 6.361 1.00 11.48 ? 405 ILE A CG2 1 ATOM 2997 C CD1 . ILE A 1 378 ? -24.138 -38.206 9.596 1.00 7.13 ? 405 ILE A CD1 1 ATOM 2998 N N . SER A 1 379 ? -22.294 -39.315 4.287 1.00 14.51 ? 406 SER A N 1 ATOM 2999 C CA . SER A 1 379 ? -21.260 -39.422 3.272 1.00 14.74 ? 406 SER A CA 1 ATOM 3000 C C . SER A 1 379 ? -20.534 -38.094 3.134 1.00 19.65 ? 406 SER A C 1 ATOM 3001 O O . SER A 1 379 ? -20.607 -37.239 4.017 1.00 19.73 ? 406 SER A O 1 ATOM 3002 C CB . SER A 1 379 ? -21.863 -39.831 1.928 1.00 20.14 ? 406 SER A CB 1 ATOM 3003 O OG . SER A 1 379 ? -22.808 -38.876 1.478 1.00 23.20 ? 406 SER A OG 1 ATOM 3004 N N . GLY A 1 380 ? -19.841 -37.918 2.015 1.00 21.85 ? 407 GLY A N 1 ATOM 3005 C CA . GLY A 1 380 ? -18.985 -36.762 1.845 1.00 23.75 ? 407 GLY A CA 1 ATOM 3006 C C . GLY A 1 380 ? -19.544 -35.742 0.884 1.00 26.33 ? 407 GLY A C 1 ATOM 3007 O O . GLY A 1 380 ? -19.213 -34.556 0.971 1.00 26.15 ? 407 GLY A O 1 ATOM 3008 N N . ASP A 1 381 ? -20.395 -36.207 -0.027 1.00 27.87 ? 408 ASP A N 1 ATOM 3009 C CA . ASP A 1 381 ? -20.973 -35.345 -1.056 1.00 28.70 ? 408 ASP A CA 1 ATOM 3010 C C . ASP A 1 381 ? -22.408 -34.932 -0.746 1.00 27.72 ? 408 ASP A C 1 ATOM 3011 O O . ASP A 1 381 ? -22.935 -34.005 -1.361 1.00 33.39 ? 408 ASP A O 1 ATOM 3012 C CB . ASP A 1 381 ? -20.946 -36.044 -2.414 1.00 27.55 ? 408 ASP A CB 1 ATOM 3013 C CG . ASP A 1 381 ? -19.587 -36.592 -2.757 1.00 33.04 ? 408 ASP A CG 1 ATOM 3014 O OD1 . ASP A 1 381 ? -18.585 -35.863 -2.583 1.00 30.78 ? 408 ASP A OD1 1 ATOM 3015 O OD2 . ASP A 1 381 ? -19.526 -37.759 -3.195 1.00 42.82 1 408 ASP A OD2 1 ATOM 3016 N N . ILE A 1 382 ? -23.038 -35.620 0.199 1.00 22.13 ? 409 ILE A N 1 ATOM 3017 C CA . ILE A 1 382 ? -24.445 -35.384 0.496 1.00 22.48 ? 409 ILE A CA 1 ATOM 3018 C C . ILE A 1 382 ? -24.743 -33.939 0.910 1.00 23.58 ? 409 ILE A C 1 ATOM 3019 O O . ILE A 1 382 ? -25.831 -33.434 0.643 1.00 29.81 ? 409 ILE A O 1 ATOM 3020 C CB . ILE A 1 382 ? -24.975 -36.367 1.566 1.00 26.73 ? 409 ILE A CB 1 ATOM 3021 C CG1 . ILE A 1 382 ? -26.495 -36.231 1.731 1.00 22.17 ? 409 ILE A CG1 1 ATOM 3022 C CG2 . ILE A 1 382 ? -24.250 -36.164 2.892 1.00 24.42 ? 409 ILE A CG2 1 ATOM 3023 C CD1 . ILE A 1 382 ? -27.286 -36.543 0.478 1.00 21.23 ? 409 ILE A CD1 1 ATOM 3024 N N . PHE A 1 383 ? -23.780 -33.268 1.536 1.00 18.32 ? 410 PHE A N 1 ATOM 3025 C CA . PHE A 1 383 ? -23.995 -31.895 1.996 1.00 18.79 ? 410 PHE A CA 1 ATOM 3026 C C . PHE A 1 383 ? -22.984 -30.912 1.422 1.00 25.17 ? 410 PHE A C 1 ATOM 3027 O O . PHE A 1 383 ? -22.877 -29.774 1.884 1.00 22.42 ? 410 PHE A O 1 ATOM 3028 C CB . PHE A 1 383 ? -23.926 -31.835 3.513 1.00 19.91 ? 410 PHE A CB 1 ATOM 3029 C CG . PHE A 1 383 ? -24.880 -32.759 4.195 1.00 22.27 ? 410 PHE A CG 1 ATOM 3030 C CD1 . PHE A 1 383 ? -26.155 -32.948 3.694 1.00 22.70 ? 410 PHE A CD1 1 ATOM 3031 C CD2 . PHE A 1 383 ? -24.505 -33.439 5.338 1.00 20.92 ? 410 PHE A CD2 1 ATOM 3032 C CE1 . PHE A 1 383 ? -27.035 -33.795 4.319 1.00 19.20 ? 410 PHE A CE1 1 ATOM 3033 C CE2 . PHE A 1 383 ? -25.379 -34.284 5.964 1.00 15.99 ? 410 PHE A CE2 1 ATOM 3034 C CZ . PHE A 1 383 ? -26.648 -34.462 5.453 1.00 15.98 ? 410 PHE A CZ 1 ATOM 3035 N N . SER A 1 384 ? -22.257 -31.357 0.403 1.00 29.77 ? 411 SER A N 1 ATOM 3036 C CA . SER A 1 384 ? -21.135 -30.608 -0.154 1.00 27.31 ? 411 SER A CA 1 ATOM 3037 C C . SER A 1 384 ? -21.533 -29.377 -0.961 1.00 31.30 ? 411 SER A C 1 ATOM 3038 O O . SER A 1 384 ? -20.739 -28.870 -1.754 1.00 28.87 ? 411 SER A O 1 ATOM 3039 C CB . SER A 1 384 ? -20.301 -31.533 -1.032 1.00 26.38 ? 411 SER A CB 1 ATOM 3040 O OG . SER A 1 384 ? -21.132 -32.217 -1.948 1.00 24.76 ? 411 SER A OG 1 ATOM 3041 N N . ASN A 1 385 ? -22.759 -28.903 -0.759 1.00 41.38 ? 412 ASN A N 1 ATOM 3042 C CA . ASN A 1 385 ? -23.261 -27.719 -1.450 1.00 38.94 ? 412 ASN A CA 1 ATOM 3043 C C . ASN A 1 385 ? -24.069 -26.822 -0.522 1.00 33.34 ? 412 ASN A C 1 ATOM 3044 O O . ASN A 1 385 ? -24.397 -25.685 -0.864 1.00 33.61 ? 412 ASN A O 1 ATOM 3045 C CB . ASN A 1 385 ? -24.123 -28.123 -2.646 1.00 35.89 ? 412 ASN A CB 1 ATOM 3046 C CG . ASN A 1 385 ? -23.336 -28.868 -3.705 1.00 37.84 ? 412 ASN A CG 1 ATOM 3047 O OD1 . ASN A 1 385 ? -23.393 -30.098 -3.791 1.00 37.20 ? 412 ASN A OD1 1 ATOM 3048 N ND2 . ASN A 1 385 ? -22.590 -28.124 -4.516 1.00 37.69 ? 412 ASN A ND2 1 ATOM 3049 N N . LEU A 1 386 ? -24.381 -27.340 0.660 1.00 27.07 ? 413 LEU A N 1 ATOM 3050 C CA . LEU A 1 386 ? -25.239 -26.631 1.593 1.00 27.63 ? 413 LEU A CA 1 ATOM 3051 C C . LEU A 1 386 ? -24.457 -25.645 2.452 1.00 26.48 ? 413 LEU A C 1 ATOM 3052 O O . LEU A 1 386 ? -24.467 -25.726 3.684 1.00 28.37 ? 413 LEU A O 1 ATOM 3053 C CB . LEU A 1 386 ? -26.002 -27.624 2.471 1.00 30.34 ? 413 LEU A CB 1 ATOM 3054 C CG . LEU A 1 386 ? -26.754 -28.743 1.739 1.00 33.10 ? 413 LEU A CG 1 ATOM 3055 C CD1 . LEU A 1 386 ? -27.592 -29.560 2.717 1.00 24.75 ? 413 LEU A CD1 1 ATOM 3056 C CD2 . LEU A 1 386 ? -27.620 -28.192 0.610 1.00 31.58 ? 413 LEU A CD2 1 ATOM 3057 N N . GLY A 1 387 ? -23.791 -24.699 1.800 1.00 22.65 ? 414 GLY A N 1 ATOM 3058 C CA . GLY A 1 387 ? -23.048 -23.679 2.513 1.00 29.42 ? 414 GLY A CA 1 ATOM 3059 C C . GLY A 1 387 ? -23.959 -22.750 3.288 1.00 27.70 ? 414 GLY A C 1 ATOM 3060 O O . GLY A 1 387 ? -23.509 -21.992 4.146 1.00 22.90 ? 414 GLY A O 1 ATOM 3061 N N . ASN A 1 388 ? -25.252 -22.823 2.985 1.00 31.15 ? 415 ASN A N 1 ATOM 3062 C CA . ASN A 1 388 ? -26.243 -21.937 3.580 1.00 25.86 ? 415 ASN A CA 1 ATOM 3063 C C . ASN A 1 388 ? -27.021 -22.588 4.716 1.00 22.89 ? 415 ASN A C 1 ATOM 3064 O O . ASN A 1 388 ? -27.576 -21.894 5.571 1.00 19.53 ? 415 ASN A O 1 ATOM 3065 C CB . ASN A 1 388 ? -27.199 -21.437 2.503 1.00 22.94 ? 415 ASN A CB 1 ATOM 3066 C CG . ASN A 1 388 ? -26.495 -20.622 1.441 1.00 35.47 ? 415 ASN A CG 1 ATOM 3067 O OD1 . ASN A 1 388 ? -26.542 -19.391 1.457 1.00 39.19 ? 415 ASN A OD1 1 ATOM 3068 N ND2 . ASN A 1 388 ? -25.821 -21.303 0.517 1.00 37.76 ? 415 ASN A ND2 1 ATOM 3069 N N . LEU A 1 389 ? -27.051 -23.920 4.711 1.00 21.12 ? 416 LEU A N 1 ATOM 3070 C CA . LEU A 1 389 ? -27.695 -24.722 5.753 1.00 17.96 ? 416 LEU A CA 1 ATOM 3071 C C . LEU A 1 389 ? -27.327 -24.265 7.161 1.00 16.50 ? 416 LEU A C 1 ATOM 3072 O O . LEU A 1 389 ? -26.199 -24.455 7.598 1.00 20.91 ? 416 LEU A O 1 ATOM 3073 C CB . LEU A 1 389 ? -27.289 -26.182 5.582 1.00 19.06 ? 416 LEU A CB 1 ATOM 3074 C CG . LEU A 1 389 ? -27.919 -27.205 6.522 1.00 20.61 ? 416 LEU A CG 1 ATOM 3075 C CD1 . LEU A 1 389 ? -29.271 -27.643 5.990 1.00 21.27 ? 416 LEU A CD1 1 ATOM 3076 C CD2 . LEU A 1 389 ? -26.995 -28.398 6.699 1.00 20.57 ? 416 LEU A CD2 1 ATOM 3077 N N . VAL A 1 390 ? -28.282 -23.672 7.868 1.00 13.13 ? 417 VAL A N 1 ATOM 3078 C CA . VAL A 1 390 ? -28.006 -23.058 9.159 1.00 13.60 ? 417 VAL A CA 1 ATOM 3079 C C . VAL A 1 390 ? -28.178 -24.019 10.323 1.00 16.55 ? 417 VAL A C 1 ATOM 3080 O O . VAL A 1 390 ? -27.364 -24.037 11.241 1.00 24.77 ? 417 VAL A O 1 ATOM 3081 C CB . VAL A 1 390 ? -28.880 -21.816 9.395 1.00 15.25 ? 417 VAL A CB 1 ATOM 3082 C CG1 . VAL A 1 390 ? -28.646 -21.251 10.786 1.00 15.88 ? 417 VAL A CG1 1 ATOM 3083 C CG2 . VAL A 1 390 ? -28.575 -20.765 8.350 1.00 21.07 ? 417 VAL A CG2 1 ATOM 3084 N N . THR A 1 391 ? -29.237 -24.814 10.303 1.00 14.36 ? 418 THR A N 1 ATOM 3085 C CA . THR A 1 391 ? -29.442 -25.775 11.382 1.00 16.16 ? 418 THR A CA 1 ATOM 3086 C C . THR A 1 391 ? -29.912 -27.134 10.866 1.00 16.38 ? 418 THR A C 1 ATOM 3087 O O . THR A 1 391 ? -30.765 -27.215 9.984 1.00 13.98 ? 418 THR A O 1 ATOM 3088 C CB . THR A 1 391 ? -30.397 -25.233 12.465 1.00 14.71 ? 418 THR A CB 1 ATOM 3089 O OG1 . THR A 1 391 ? -31.306 -26.267 12.857 1.00 13.52 ? 418 THR A OG1 1 ATOM 3090 C CG2 . THR A 1 391 ? -31.179 -24.033 11.947 1.00 13.25 ? 418 THR A CG2 1 ATOM 3091 N N . LEU A 1 392 ? -29.345 -28.200 11.424 1.00 17.18 ? 419 LEU A N 1 ATOM 3092 C CA . LEU A 1 392 ? -29.563 -29.546 10.902 1.00 14.33 ? 419 LEU A CA 1 ATOM 3093 C C . LEU A 1 392 ? -29.900 -30.567 11.986 1.00 14.15 ? 419 LEU A C 1 ATOM 3094 O O . LEU A 1 392 ? -29.333 -30.547 13.075 1.00 14.18 ? 419 LEU A O 1 ATOM 3095 C CB . LEU A 1 392 ? -28.331 -30.009 10.136 1.00 12.07 ? 419 LEU A CB 1 ATOM 3096 C CG . LEU A 1 392 ? -28.392 -31.428 9.591 1.00 10.73 ? 419 LEU A CG 1 ATOM 3097 C CD1 . LEU A 1 392 ? -28.621 -31.393 8.095 1.00 15.48 ? 419 LEU A CD1 1 ATOM 3098 C CD2 . LEU A 1 392 ? -27.119 -32.148 9.925 1.00 13.27 ? 419 LEU A CD2 1 ATOM 3099 N N . VAL A 1 393 ? -30.828 -31.464 11.671 1.00 13.83 ? 420 VAL A N 1 ATOM 3100 C CA . VAL A 1 393 ? -31.311 -32.441 12.632 1.00 14.25 ? 420 VAL A CA 1 ATOM 3101 C C . VAL A 1 393 ? -31.285 -33.843 12.031 1.00 11.71 ? 420 VAL A C 1 ATOM 3102 O O . VAL A 1 393 ? -31.768 -34.058 10.922 1.00 8.86 ? 420 VAL A O 1 ATOM 3103 C CB . VAL A 1 393 ? -32.758 -32.114 13.082 1.00 15.91 ? 420 VAL A CB 1 ATOM 3104 C CG1 . VAL A 1 393 ? -33.204 -33.064 14.180 1.00 15.24 ? 420 VAL A CG1 1 ATOM 3105 C CG2 . VAL A 1 393 ? -32.869 -30.668 13.554 1.00 14.19 ? 420 VAL A CG2 1 ATOM 3106 N N . MET A 1 394 ? -30.701 -34.788 12.760 1.00 12.98 ? 421 MET A N 1 ATOM 3107 C CA . MET A 1 394 ? -30.738 -36.196 12.377 1.00 10.86 ? 421 MET A CA 1 ATOM 3108 C C . MET A 1 394 ? -30.922 -37.024 13.627 1.00 10.39 ? 421 MET A C 1 ATOM 3109 O O . MET A 1 394 ? -30.486 -38.171 13.695 1.00 11.24 ? 421 MET A O 1 ATOM 3110 C CB . MET A 1 394 ? -29.450 -36.629 11.689 1.00 10.64 ? 421 MET A CB 1 ATOM 3111 C CG . MET A 1 394 ? -28.985 -35.711 10.594 1.00 10.05 ? 421 MET A CG 1 ATOM 3112 S SD . MET A 1 394 ? -28.072 -36.620 9.354 1.00 6.61 ? 421 MET A SD 1 ATOM 3113 C CE . MET A 1 394 ? -27.176 -35.283 8.622 1.00 7.01 ? 421 MET A CE 1 ATOM 3114 N N . SER A 1 395 ? -31.558 -36.419 14.619 1.00 9.09 ? 422 SER A N 1 ATOM 3115 C CA . SER A 1 395 ? -31.826 -37.077 15.885 1.00 12.35 ? 422 SER A CA 1 ATOM 3116 C C . SER A 1 395 ? -32.562 -38.397 15.696 1.00 12.82 ? 422 SER A C 1 ATOM 3117 O O . SER A 1 395 ? -33.336 -38.559 14.760 1.00 11.39 ? 422 SER A O 1 ATOM 3118 C CB . SER A 1 395 ? -32.661 -36.151 16.761 1.00 16.11 ? 422 SER A CB 1 ATOM 3119 O OG . SER A 1 395 ? -32.215 -34.815 16.628 1.00 16.85 ? 422 SER A OG 1 ATOM 3120 N N . ARG A 1 396 ? -32.316 -39.337 16.597 1.00 14.02 ? 423 ARG A N 1 ATOM 3121 C CA . ARG A 1 396 ? -33.012 -40.612 16.571 1.00 13.79 ? 423 ARG A CA 1 ATOM 3122 C C . ARG A 1 396 ? -32.988 -41.272 15.202 1.00 12.41 ? 423 ARG A C 1 ATOM 3123 O O . ARG A 1 396 ? -34.031 -41.588 14.641 1.00 14.75 ? 423 ARG A O 1 ATOM 3124 C CB . ARG A 1 396 ? -34.457 -40.448 17.048 1.00 15.69 ? 423 ARG A CB 1 ATOM 3125 C CG . ARG A 1 396 ? -34.590 -40.173 18.540 1.00 16.76 ? 423 ARG A CG 1 ATOM 3126 C CD . ARG A 1 396 ? -36.036 -39.923 18.931 1.00 14.86 ? 423 ARG A CD 1 ATOM 3127 N NE . ARG A 1 396 ? -36.599 -38.796 18.197 1.00 16.12 ? 423 ARG A NE 1 ATOM 3128 C CZ . ARG A 1 396 ? -36.462 -37.529 18.569 1.00 17.29 ? 423 ARG A CZ 1 ATOM 3129 N NH1 . ARG A 1 396 ? -35.784 -37.237 19.672 1.00 16.51 1 423 ARG A NH1 1 ATOM 3130 N NH2 . ARG A 1 396 ? -37.002 -36.557 17.841 1.00 15.26 ? 423 ARG A NH2 1 ATOM 3131 N N . ASN A 1 397 ? -31.793 -41.449 14.655 1.00 12.69 ? 424 ASN A N 1 ATOM 3132 C CA . ASN A 1 397 ? -31.607 -42.362 13.537 1.00 13.01 ? 424 ASN A CA 1 ATOM 3133 C C . ASN A 1 397 ? -30.732 -43.525 13.963 1.00 17.83 ? 424 ASN A C 1 ATOM 3134 O O . ASN A 1 397 ? -30.702 -43.903 15.141 1.00 21.26 ? 424 ASN A O 1 ATOM 3135 C CB . ASN A 1 397 ? -30.991 -41.658 12.333 1.00 12.08 ? 424 ASN A CB 1 ATOM 3136 C CG . ASN A 1 397 ? -31.948 -40.688 11.681 1.00 13.87 ? 424 ASN A CG 1 ATOM 3137 O OD1 . ASN A 1 397 ? -32.597 -39.895 12.359 1.00 14.15 ? 424 ASN A OD1 1 ATOM 3138 N ND2 . ASN A 1 397 ? -32.057 -40.760 10.362 1.00 11.97 ? 424 ASN A ND2 1 ATOM 3139 N N . ARG A 1 398 ? -30.026 -44.098 12.999 1.00 16.82 ? 425 ARG A N 1 ATOM 3140 C CA . ARG A 1 398 ? -29.058 -45.141 13.291 1.00 20.29 ? 425 ARG A CA 1 ATOM 3141 C C . ARG A 1 398 ? -27.748 -44.803 12.586 1.00 18.48 ? 425 ARG A C 1 ATOM 3142 O O . ARG A 1 398 ? -27.132 -45.663 11.957 1.00 20.12 ? 425 ARG A O 1 ATOM 3143 C CB . ARG A 1 398 ? -29.587 -46.517 12.864 1.00 20.71 ? 425 ARG A CB 1 ATOM 3144 C CG . ARG A 1 398 ? -30.977 -46.850 13.412 1.00 21.02 ? 425 ARG A CG 1 ATOM 3145 C CD . ARG A 1 398 ? -30.984 -48.129 14.245 1.00 35.50 ? 425 ARG A CD 1 ATOM 3146 N NE . ARG A 1 398 ? -30.214 -47.997 15.482 1.00 46.15 ? 425 ARG A NE 1 ATOM 3147 C CZ . ARG A 1 398 ? -30.559 -48.539 16.648 1.00 50.49 ? 425 ARG A CZ 1 ATOM 3148 N NH1 . ARG A 1 398 ? -31.669 -49.260 16.754 1.00 54.52 1 425 ARG A NH1 1 ATOM 3149 N NH2 . ARG A 1 398 ? -29.793 -48.358 17.715 1.00 46.39 ? 425 ARG A NH2 1 ATOM 3150 N N . LEU A 1 399 ? -27.345 -43.536 12.680 1.00 15.93 ? 426 LEU A N 1 ATOM 3151 C CA . LEU A 1 399 ? -26.079 -43.080 12.113 1.00 13.88 ? 426 LEU A CA 1 ATOM 3152 C C . LEU A 1 399 ? -24.925 -43.752 12.828 1.00 14.83 ? 426 LEU A C 1 ATOM 3153 O O . LEU A 1 399 ? -24.884 -43.794 14.057 1.00 17.98 ? 426 LEU A O 1 ATOM 3154 C CB . LEU A 1 399 ? -25.932 -41.561 12.243 1.00 16.35 ? 426 LEU A CB 1 ATOM 3155 C CG . LEU A 1 399 ? -26.884 -40.626 11.485 1.00 16.17 ? 426 LEU A CG 1 ATOM 3156 C CD1 . LEU A 1 399 ? -26.704 -39.181 11.958 1.00 12.13 ? 426 LEU A CD1 1 ATOM 3157 C CD2 . LEU A 1 399 ? -26.697 -40.725 9.972 1.00 10.94 ? 426 LEU A CD2 1 ATOM 3158 N N . ARG A 1 400 ? -23.984 -44.275 12.053 1.00 15.95 ? 427 ARG A N 1 ATOM 3159 C CA . ARG A 1 400 ? -22.823 -44.967 12.606 1.00 17.69 ? 427 ARG A CA 1 ATOM 3160 C C . ARG A 1 400 ? -21.523 -44.402 12.033 1.00 14.69 ? 427 ARG A C 1 ATOM 3161 O O . ARG A 1 400 ? -20.479 -44.439 12.678 1.00 19.49 ? 427 ARG A O 1 ATOM 3162 C CB . ARG A 1 400 ? -22.917 -46.470 12.318 1.00 15.76 ? 427 ARG A CB 1 ATOM 3163 C CG . ARG A 1 400 ? -21.681 -47.266 12.697 1.00 19.17 ? 427 ARG A CG 1 ATOM 3164 C CD . ARG A 1 400 ? -21.766 -48.712 12.218 1.00 31.23 ? 427 ARG A CD 1 ATOM 3165 N NE . ARG A 1 400 ? -20.515 -49.434 12.457 1.00 36.59 ? 427 ARG A NE 1 ATOM 3166 C CZ . ARG A 1 400 ? -20.280 -50.685 12.071 1.00 32.28 ? 427 ARG A CZ 1 ATOM 3167 N NH1 . ARG A 1 400 ? -21.212 -51.372 11.422 1.00 27.66 1 427 ARG A NH1 1 ATOM 3168 N NH2 . ARG A 1 400 ? -19.108 -51.250 12.332 1.00 33.79 ? 427 ARG A NH2 1 ATOM 3169 N N . THR A 1 401 ? -21.604 -43.849 10.830 1.00 12.68 ? 428 THR A N 1 ATOM 3170 C CA . THR A 1 401 ? -20.414 -43.484 10.087 1.00 10.50 ? 428 THR A CA 1 ATOM 3171 C C . THR A 1 401 ? -20.504 -42.091 9.493 1.00 9.07 ? 428 THR A C 1 ATOM 3172 O O . THR A 1 401 ? -20.920 -41.926 8.350 1.00 9.52 ? 428 THR A O 1 ATOM 3173 C CB . THR A 1 401 ? -20.177 -44.474 8.931 1.00 16.21 ? 428 THR A CB 1 ATOM 3174 O OG1 . THR A 1 401 ? -20.328 -45.817 9.407 1.00 19.81 ? 428 THR A OG1 1 ATOM 3175 C CG2 . THR A 1 401 ? -18.784 -44.302 8.346 1.00 22.89 ? 428 THR A CG2 1 ATOM 3176 N N . ILE A 1 402 ? -20.109 -41.087 10.264 1.00 8.27 ? 429 ILE A N 1 ATOM 3177 C CA . ILE A 1 402 ? -19.917 -39.759 9.705 1.00 8.25 ? 429 ILE A CA 1 ATOM 3178 C C . ILE A 1 402 ? -18.562 -39.692 9.009 1.00 12.49 ? 429 ILE A C 1 ATOM 3179 O O . ILE A 1 402 ? -17.515 -39.761 9.654 1.00 11.73 ? 429 ILE A O 1 ATOM 3180 C CB . ILE A 1 402 ? -19.943 -38.670 10.771 1.00 7.06 ? 429 ILE A CB 1 ATOM 3181 C CG1 . ILE A 1 402 ? -21.129 -38.861 11.707 1.00 8.28 ? 429 ILE A CG1 1 ATOM 3182 C CG2 . ILE A 1 402 ? -19.982 -37.311 10.122 1.00 7.29 ? 429 ILE A CG2 1 ATOM 3183 C CD1 . ILE A 1 402 ? -21.106 -37.927 12.889 1.00 10.46 ? 429 ILE A CD1 1 ATOM 3184 N N . ASP A 1 403 ? -18.599 -39.567 7.687 1.00 14.93 ? 430 ASP A N 1 ATOM 3185 C CA . ASP A 1 403 ? -17.414 -39.376 6.869 1.00 12.20 ? 430 ASP A CA 1 ATOM 3186 C C . ASP A 1 403 ? -16.617 -38.202 7.405 1.00 15.99 ? 430 ASP A C 1 ATOM 3187 O O . ASP A 1 403 ? -17.151 -37.343 8.102 1.00 17.52 ? 430 ASP A O 1 ATOM 3188 C CB . ASP A 1 403 ? -17.846 -39.089 5.433 1.00 16.15 ? 430 ASP A CB 1 ATOM 3189 C CG . ASP A 1 403 ? -16.682 -38.965 4.478 1.00 21.61 ? 430 ASP A CG 1 ATOM 3190 O OD1 . ASP A 1 403 ? -16.001 -37.920 4.505 1.00 21.88 ? 430 ASP A OD1 1 ATOM 3191 O OD2 . ASP A 1 403 ? -16.462 -39.906 3.684 1.00 23.39 1 430 ASP A OD2 1 ATOM 3192 N N . SER A 1 404 ? -15.331 -38.169 7.085 1.00 19.78 ? 431 SER A N 1 ATOM 3193 C CA . SER A 1 404 ? -14.482 -37.058 7.485 1.00 23.72 ? 431 SER A CA 1 ATOM 3194 C C . SER A 1 404 ? -14.801 -35.833 6.636 1.00 24.66 ? 431 SER A C 1 ATOM 3195 O O . SER A 1 404 ? -15.001 -34.733 7.153 1.00 27.48 ? 431 SER A O 1 ATOM 3196 C CB . SER A 1 404 ? -13.012 -37.438 7.329 1.00 23.57 ? 431 SER A CB 1 ATOM 3197 O OG . SER A 1 404 ? -12.756 -37.926 6.022 1.00 20.69 ? 431 SER A OG 1 ATOM 3198 N N . ARG A 1 405 ? -14.869 -36.041 5.327 1.00 19.96 ? 432 ARG A N 1 ATOM 3199 C CA . ARG A 1 405 ? -15.109 -34.955 4.390 1.00 24.29 ? 432 ARG A CA 1 ATOM 3200 C C . ARG A 1 405 ? -16.577 -34.505 4.430 1.00 33.46 ? 432 ARG A C 1 ATOM 3201 O O . ARG A 1 405 ? -16.976 -33.585 3.710 1.00 40.90 ? 432 ARG A O 1 ATOM 3202 C CB . ARG A 1 405 ? -14.710 -35.404 2.979 1.00 23.73 ? 432 ARG A CB 1 ATOM 3203 C CG . ARG A 1 405 ? -14.556 -34.278 1.969 1.00 34.87 ? 432 ARG A CG 1 ATOM 3204 C CD . ARG A 1 405 ? -13.858 -34.753 0.707 1.00 45.33 ? 432 ARG A CD 1 ATOM 3205 N NE . ARG A 1 405 ? -13.923 -33.774 -0.380 1.00 60.37 ? 432 ARG A NE 1 ATOM 3206 C CZ . ARG A 1 405 ? -13.143 -32.700 -0.484 1.00 53.08 ? 432 ARG A CZ 1 ATOM 3207 N NH1 . ARG A 1 405 ? -12.232 -32.441 0.449 1.00 41.42 1 432 ARG A NH1 1 ATOM 3208 N NH2 . ARG A 1 405 ? -13.279 -31.878 -1.520 1.00 40.97 ? 432 ARG A NH2 1 ATOM 3209 N N . ALA A 1 406 ? -17.369 -35.147 5.288 1.00 31.10 ? 433 ALA A N 1 ATOM 3210 C CA . ALA A 1 406 ? -18.811 -34.892 5.378 1.00 27.33 ? 433 ALA A CA 1 ATOM 3211 C C . ALA A 1 406 ? -19.187 -33.417 5.554 1.00 29.44 ? 433 ALA A C 1 ATOM 3212 O O . ALA A 1 406 ? -19.990 -32.893 4.783 1.00 22.52 ? 433 ALA A O 1 ATOM 3213 C CB . ALA A 1 406 ? -19.431 -35.732 6.491 1.00 19.50 ? 433 ALA A CB 1 ATOM 3214 N N . PHE A 1 407 ? -18.590 -32.757 6.549 1.00 31.57 ? 434 PHE A N 1 ATOM 3215 C CA . PHE A 1 407 ? -19.000 -31.408 6.955 1.00 28.70 ? 434 PHE A CA 1 ATOM 3216 C C . PHE A 1 407 ? -18.014 -30.287 6.619 1.00 27.59 ? 434 PHE A C 1 ATOM 3217 O O . PHE A 1 407 ? -17.843 -29.350 7.402 1.00 25.26 ? 434 PHE A O 1 ATOM 3218 C CB . PHE A 1 407 ? -19.275 -31.379 8.458 1.00 23.54 ? 434 PHE A CB 1 ATOM 3219 C CG . PHE A 1 407 ? -20.458 -32.191 8.871 1.00 21.68 ? 434 PHE A CG 1 ATOM 3220 C CD1 . PHE A 1 407 ? -21.735 -31.660 8.797 1.00 26.74 ? 434 PHE A CD1 1 ATOM 3221 C CD2 . PHE A 1 407 ? -20.299 -33.483 9.336 1.00 21.08 ? 434 PHE A CD2 1 ATOM 3222 C CE1 . PHE A 1 407 ? -22.838 -32.406 9.180 1.00 27.05 ? 434 PHE A CE1 1 ATOM 3223 C CE2 . PHE A 1 407 ? -21.394 -34.235 9.719 1.00 23.86 ? 434 PHE A CE2 1 ATOM 3224 C CZ . PHE A 1 407 ? -22.666 -33.698 9.641 1.00 24.70 ? 434 PHE A CZ 1 ATOM 3225 N N . VAL A 1 408 ? -17.386 -30.362 5.455 1.00 27.27 ? 435 VAL A N 1 ATOM 3226 C CA . VAL A 1 408 ? -16.347 -29.397 5.116 1.00 29.38 ? 435 VAL A CA 1 ATOM 3227 C C . VAL A 1 408 ? -16.903 -28.106 4.501 1.00 32.19 ? 435 VAL A C 1 ATOM 3228 O O . VAL A 1 408 ? -16.356 -27.021 4.712 1.00 31.96 ? 435 VAL A O 1 ATOM 3229 C CB . VAL A 1 408 ? -15.275 -30.028 4.201 1.00 24.86 ? 435 VAL A CB 1 ATOM 3230 C CG1 . VAL A 1 408 ? -15.907 -30.546 2.920 1.00 30.88 ? 435 VAL A CG1 1 ATOM 3231 C CG2 . VAL A 1 408 ? -14.162 -29.036 3.907 1.00 21.46 ? 435 VAL A CG2 1 ATOM 3232 N N . SER A 1 409 ? -18.002 -28.221 3.759 1.00 32.97 ? 436 SER A N 1 ATOM 3233 C CA . SER A 1 409 ? -18.567 -27.068 3.060 1.00 31.68 ? 436 SER A CA 1 ATOM 3234 C C . SER A 1 409 ? -19.707 -26.413 3.829 1.00 23.58 ? 436 SER A C 1 ATOM 3235 O O . SER A 1 409 ? -20.152 -25.323 3.485 1.00 24.44 ? 436 SER A O 1 ATOM 3236 C CB . SER A 1 409 ? -19.034 -27.462 1.655 1.00 26.83 ? 436 SER A CB 1 ATOM 3237 O OG . SER A 1 409 ? -17.928 -27.818 0.842 1.00 21.52 ? 436 SER A OG 1 ATOM 3238 N N . THR A 1 410 ? -20.173 -27.077 4.876 1.00 19.56 ? 437 THR A N 1 ATOM 3239 C CA . THR A 1 410 ? -21.283 -26.561 5.659 1.00 21.08 ? 437 THR A CA 1 ATOM 3240 C C . THR A 1 410 ? -20.815 -25.496 6.660 1.00 27.67 ? 437 THR A C 1 ATOM 3241 O O . THR A 1 410 ? -20.992 -25.630 7.876 1.00 29.19 ? 437 THR A O 1 ATOM 3242 C CB . THR A 1 410 ? -22.025 -27.703 6.378 1.00 23.33 ? 437 THR A CB 1 ATOM 3243 O OG1 . THR A 1 410 ? -21.083 -28.514 7.089 1.00 28.78 ? 437 THR A OG1 1 ATOM 3244 C CG2 . THR A 1 410 ? -22.756 -28.578 5.374 1.00 17.74 ? 437 THR A CG2 1 ATOM 3245 N N . ASN A 1 411 ? -20.217 -24.431 6.138 1.00 24.40 ? 438 ASN A N 1 ATOM 3246 C CA . ASN A 1 411 ? -19.755 -23.332 6.977 1.00 25.72 ? 438 ASN A CA 1 ATOM 3247 C C . ASN A 1 411 ? -20.898 -22.448 7.466 1.00 23.63 ? 438 ASN A C 1 ATOM 3248 O O . ASN A 1 411 ? -20.698 -21.554 8.285 1.00 21.31 ? 438 ASN A O 1 ATOM 3249 C CB . ASN A 1 411 ? -18.717 -22.496 6.228 1.00 26.83 ? 438 ASN A CB 1 ATOM 3250 C CG . ASN A 1 411 ? -18.903 -22.553 4.723 1.00 31.89 ? 438 ASN A CG 1 ATOM 3251 O OD1 . ASN A 1 411 ? -18.258 -23.349 4.039 1.00 32.30 ? 438 ASN A OD1 1 ATOM 3252 N ND2 . ASN A 1 411 ? -19.791 -21.711 4.198 1.00 31.17 ? 438 ASN A ND2 1 ATOM 3253 N N . GLY A 1 412 ? -22.098 -22.704 6.957 1.00 28.97 ? 439 GLY A N 1 ATOM 3254 C CA . GLY A 1 412 ? -23.266 -21.934 7.343 1.00 26.73 ? 439 GLY A CA 1 ATOM 3255 C C . GLY A 1 412 ? -23.989 -22.546 8.525 1.00 24.90 ? 439 GLY A C 1 ATOM 3256 O O . GLY A 1 412 ? -24.906 -21.940 9.085 1.00 22.10 ? 439 GLY A O 1 ATOM 3257 N N . LEU A 1 413 ? -23.567 -23.749 8.907 1.00 24.27 ? 440 LEU A N 1 ATOM 3258 C CA . LEU A 1 413 ? -24.206 -24.484 9.992 1.00 18.95 ? 440 LEU A CA 1 ATOM 3259 C C . LEU A 1 413 ? -23.900 -23.848 11.336 1.00 16.55 ? 440 LEU A C 1 ATOM 3260 O O . LEU A 1 413 ? -22.817 -23.318 11.542 1.00 21.28 ? 440 LEU A O 1 ATOM 3261 C CB . LEU A 1 413 ? -23.766 -25.948 9.975 1.00 17.29 ? 440 LEU A CB 1 ATOM 3262 C CG . LEU A 1 413 ? -24.593 -26.953 10.776 1.00 14.47 ? 440 LEU A CG 1 ATOM 3263 C CD1 . LEU A 1 413 ? -26.063 -26.813 10.466 1.00 12.37 ? 440 LEU A CD1 1 ATOM 3264 C CD2 . LEU A 1 413 ? -24.127 -28.362 10.460 1.00 15.94 ? 440 LEU A CD2 1 ATOM 3265 N N . ARG A 1 414 ? -24.872 -23.897 12.239 1.00 16.50 ? 441 ARG A N 1 ATOM 3266 C CA . ARG A 1 414 ? -24.734 -23.328 13.571 1.00 18.78 ? 441 ARG A CA 1 ATOM 3267 C C . ARG A 1 414 ? -25.249 -24.305 14.611 1.00 19.60 ? 441 ARG A C 1 ATOM 3268 O O . ARG A 1 414 ? -24.751 -24.361 15.731 1.00 19.58 ? 441 ARG A O 1 ATOM 3269 C CB . ARG A 1 414 ? -25.533 -22.035 13.676 1.00 18.81 ? 441 ARG A CB 1 ATOM 3270 C CG . ARG A 1 414 ? -25.057 -20.951 12.753 1.00 19.79 ? 441 ARG A CG 1 ATOM 3271 C CD . ARG A 1 414 ? -23.590 -20.683 12.971 1.00 19.53 ? 441 ARG A CD 1 ATOM 3272 N NE . ARG A 1 414 ? -22.856 -20.757 11.714 1.00 19.48 ? 441 ARG A NE 1 ATOM 3273 C CZ . ARG A 1 414 ? -22.304 -19.709 11.117 1.00 22.60 ? 441 ARG A CZ 1 ATOM 3274 N NH1 . ARG A 1 414 ? -22.390 -18.508 11.677 1.00 22.18 1 441 ARG A NH1 1 ATOM 3275 N NH2 . ARG A 1 414 ? -21.659 -19.864 9.967 1.00 22.78 ? 441 ARG A NH2 1 ATOM 3276 N N . HIS A 1 415 ? -26.263 -25.069 14.230 1.00 19.03 ? 442 HIS A N 1 ATOM 3277 C CA . HIS A 1 415 ? -26.897 -26.005 15.142 1.00 17.99 ? 442 HIS A CA 1 ATOM 3278 C C . HIS A 1 415 ? -26.948 -27.405 14.534 1.00 19.67 ? 442 HIS A C 1 ATOM 3279 O O . HIS A 1 415 ? -27.618 -27.634 13.525 1.00 17.71 ? 442 HIS A O 1 ATOM 3280 C CB . HIS A 1 415 ? -28.297 -25.514 15.496 1.00 18.23 ? 442 HIS A CB 1 ATOM 3281 C CG . HIS A 1 415 ? -28.344 -24.074 15.905 1.00 25.08 ? 442 HIS A CG 1 ATOM 3282 N ND1 . HIS A 1 415 ? -27.965 -23.641 17.159 1.00 23.35 ? 442 HIS A ND1 1 ATOM 3283 C CD2 . HIS A 1 415 ? -28.726 -22.965 15.225 1.00 26.83 ? 442 HIS A CD2 1 ATOM 3284 C CE1 . HIS A 1 415 ? -28.116 -22.331 17.235 1.00 26.07 ? 442 HIS A CE1 1 ATOM 3285 N NE2 . HIS A 1 415 ? -28.578 -21.896 16.075 1.00 30.06 ? 442 HIS A NE2 1 ATOM 3286 N N . LEU A 1 416 ? -26.229 -28.334 15.161 1.00 19.66 ? 443 LEU A N 1 ATOM 3287 C CA . LEU A 1 416 ? -26.085 -29.692 14.653 1.00 14.07 ? 443 LEU A CA 1 ATOM 3288 C C . LEU A 1 416 ? -26.539 -30.709 15.683 1.00 13.68 ? 443 LEU A C 1 ATOM 3289 O O . LEU A 1 416 ? -25.912 -30.865 16.722 1.00 16.26 ? 443 LEU A O 1 ATOM 3290 C CB . LEU A 1 416 ? -24.630 -29.956 14.290 1.00 13.89 ? 443 LEU A CB 1 ATOM 3291 C CG . LEU A 1 416 ? -24.262 -31.407 14.000 1.00 16.94 ? 443 LEU A CG 1 ATOM 3292 C CD1 . LEU A 1 416 ? -25.049 -31.939 12.820 1.00 13.88 ? 443 LEU A CD1 1 ATOM 3293 C CD2 . LEU A 1 416 ? -22.761 -31.526 13.750 1.00 22.41 ? 443 LEU A CD2 1 ATOM 3294 N N . HIS A 1 417 ? -27.630 -31.403 15.385 1.00 18.42 ? 444 HIS A N 1 ATOM 3295 C CA . HIS A 1 417 ? -28.212 -32.372 16.309 1.00 18.36 ? 444 HIS A CA 1 ATOM 3296 C C . HIS A 1 417 ? -28.108 -33.791 15.756 1.00 15.11 ? 444 HIS A C 1 ATOM 3297 O O . HIS A 1 417 ? -28.929 -34.188 14.930 1.00 15.82 ? 444 HIS A O 1 ATOM 3298 C CB . HIS A 1 417 ? -29.696 -32.062 16.546 1.00 15.34 ? 444 HIS A CB 1 ATOM 3299 C CG . HIS A 1 417 ? -29.978 -30.644 16.944 1.00 16.69 ? 444 HIS A CG 1 ATOM 3300 N ND1 . HIS A 1 417 ? -30.303 -30.284 18.234 1.00 16.04 ? 444 HIS A ND1 1 ATOM 3301 C CD2 . HIS A 1 417 ? -30.018 -29.503 16.214 1.00 16.87 ? 444 HIS A CD2 1 ATOM 3302 C CE1 . HIS A 1 417 ? -30.516 -28.981 18.285 1.00 14.97 ? 444 HIS A CE1 1 ATOM 3303 N NE2 . HIS A 1 417 ? -30.349 -28.483 17.074 1.00 14.51 ? 444 HIS A NE2 1 ATOM 3304 N N . LEU A 1 418 ? -27.119 -34.556 16.210 1.00 10.96 ? 445 LEU A N 1 ATOM 3305 C CA . LEU A 1 418 ? -27.021 -35.957 15.814 1.00 11.42 ? 445 LEU A CA 1 ATOM 3306 C C . LEU A 1 418 ? -27.279 -36.876 16.994 1.00 11.60 ? 445 LEU A C 1 ATOM 3307 O O . LEU A 1 418 ? -26.721 -37.964 17.068 1.00 14.52 ? 445 LEU A O 1 ATOM 3308 C CB . LEU A 1 418 ? -25.646 -36.275 15.238 1.00 12.56 ? 445 LEU A CB 1 ATOM 3309 C CG . LEU A 1 418 ? -25.032 -35.236 14.311 1.00 17.46 ? 445 LEU A CG 1 ATOM 3310 C CD1 . LEU A 1 418 ? -23.639 -34.952 14.799 1.00 15.07 ? 445 LEU A CD1 1 ATOM 3311 C CD2 . LEU A 1 418 ? -25.012 -35.712 12.864 1.00 16.11 ? 445 LEU A CD2 1 ATOM 3312 N N . ASP A 1 419 ? -28.124 -36.439 17.915 1.00 10.47 ? 446 ASP A N 1 ATOM 3313 C CA . ASP A 1 419 ? -28.386 -37.211 19.120 1.00 13.78 ? 446 ASP A CA 1 ATOM 3314 C C . ASP A 1 419 ? -29.061 -38.558 18.842 1.00 17.23 ? 446 ASP A C 1 ATOM 3315 O O . ASP A 1 419 ? -29.635 -38.772 17.774 1.00 15.47 ? 446 ASP A O 1 ATOM 3316 C CB . ASP A 1 419 ? -29.219 -36.386 20.103 1.00 17.01 ? 446 ASP A CB 1 ATOM 3317 C CG . ASP A 1 419 ? -30.418 -35.718 19.441 1.00 19.77 ? 446 ASP A CG 1 ATOM 3318 O OD1 . ASP A 1 419 ? -31.490 -36.356 19.355 1.00 19.15 1 446 ASP A OD1 1 ATOM 3319 O OD2 . ASP A 1 419 ? -30.289 -34.551 19.009 1.00 17.53 ? 446 ASP A OD2 1 ATOM 3320 N N . HIS A 1 420 ? -28.964 -39.464 19.812 1.00 18.43 ? 447 HIS A N 1 ATOM 3321 C CA . HIS A 1 420 ? -29.636 -40.761 19.767 1.00 17.00 ? 447 HIS A CA 1 ATOM 3322 C C . HIS A 1 420 ? -29.274 -41.603 18.554 1.00 17.57 ? 447 HIS A C 1 ATOM 3323 O O . HIS A 1 420 ? -30.146 -42.149 17.877 1.00 20.84 ? 447 HIS A O 1 ATOM 3324 C CB . HIS A 1 420 ? -31.145 -40.576 19.858 1.00 18.36 ? 447 HIS A CB 1 ATOM 3325 C CG . HIS A 1 420 ? -31.568 -39.704 20.997 1.00 20.54 ? 447 HIS A CG 1 ATOM 3326 N ND1 . HIS A 1 420 ? -31.795 -40.193 22.264 1.00 21.23 ? 447 HIS A ND1 1 ATOM 3327 C CD2 . HIS A 1 420 ? -31.792 -38.371 21.062 1.00 19.12 ? 447 HIS A CD2 1 ATOM 3328 C CE1 . HIS A 1 420 ? -32.146 -39.200 23.060 1.00 22.03 ? 447 HIS A CE1 1 ATOM 3329 N NE2 . HIS A 1 420 ? -32.152 -38.083 22.356 1.00 17.82 ? 447 HIS A NE2 1 ATOM 3330 N N . ASN A 1 421 ? -27.979 -41.709 18.291 1.00 16.32 ? 448 ASN A N 1 ATOM 3331 C CA . ASN A 1 421 ? -27.480 -42.579 17.241 1.00 17.62 ? 448 ASN A CA 1 ATOM 3332 C C . ASN A 1 421 ? -26.435 -43.541 17.791 1.00 21.23 ? 448 ASN A C 1 ATOM 3333 O O . ASN A 1 421 ? -26.324 -43.724 19.004 1.00 20.05 ? 448 ASN A O 1 ATOM 3334 C CB . ASN A 1 421 ? -26.894 -41.755 16.099 1.00 16.53 ? 448 ASN A CB 1 ATOM 3335 C CG . ASN A 1 421 ? -27.933 -40.906 15.404 1.00 14.47 ? 448 ASN A CG 1 ATOM 3336 O OD1 . ASN A 1 421 ? -28.411 -41.252 14.327 1.00 14.76 ? 448 ASN A OD1 1 ATOM 3337 N ND2 . ASN A 1 421 ? -28.292 -39.788 16.019 1.00 13.16 ? 448 ASN A ND2 1 ATOM 3338 N N . ASP A 1 422 ? -25.673 -44.156 16.892 1.00 21.70 ? 449 ASP A N 1 ATOM 3339 C CA . ASP A 1 422 ? -24.619 -45.080 17.281 1.00 21.06 ? 449 ASP A CA 1 ATOM 3340 C C . ASP A 1 422 ? -23.269 -44.563 16.808 1.00 22.83 ? 449 ASP A C 1 ATOM 3341 O O . ASP A 1 422 ? -22.435 -45.331 16.326 1.00 26.71 ? 449 ASP A O 1 ATOM 3342 C CB . ASP A 1 422 ? -24.877 -46.470 16.695 1.00 29.57 ? 449 ASP A CB 1 ATOM 3343 C CG . ASP A 1 422 ? -25.962 -47.230 17.438 1.00 39.57 ? 449 ASP A CG 1 ATOM 3344 O OD1 . ASP A 1 422 ? -27.145 -47.115 17.050 1.00 40.08 1 449 ASP A OD1 1 ATOM 3345 O OD2 . ASP A 1 422 ? -25.629 -47.950 18.407 1.00 37.90 ? 449 ASP A OD2 1 ATOM 3346 N N . ILE A 1 423 ? -23.053 -43.259 16.946 1.00 21.82 ? 450 ILE A N 1 ATOM 3347 C CA . ILE A 1 423 ? -21.800 -42.659 16.505 1.00 20.96 ? 450 ILE A CA 1 ATOM 3348 C C . ILE A 1 423 ? -20.740 -42.709 17.599 1.00 21.06 ? 450 ILE A C 1 ATOM 3349 O O . ILE A 1 423 ? -20.996 -42.348 18.746 1.00 17.46 ? 450 ILE A O 1 ATOM 3350 C CB . ILE A 1 423 ? -21.986 -41.204 16.038 1.00 20.59 ? 450 ILE A CB 1 ATOM 3351 C CG1 . ILE A 1 423 ? -23.347 -41.032 15.354 1.00 19.28 ? 450 ILE A CG1 1 ATOM 3352 C CG2 . ILE A 1 423 ? -20.842 -40.800 15.112 1.00 14.37 ? 450 ILE A CG2 1 ATOM 3353 C CD1 . ILE A 1 423 ? -23.648 -39.610 14.932 1.00 15.11 ? 450 ILE A CD1 1 ATOM 3354 N N . ASP A 1 424 ? -19.548 -43.162 17.219 1.00 29.84 ? 451 ASP A N 1 ATOM 3355 C CA . ASP A 1 424 ? -18.417 -43.301 18.132 1.00 26.38 ? 451 ASP A CA 1 ATOM 3356 C C . ASP A 1 424 ? -17.209 -42.529 17.613 1.00 26.22 ? 451 ASP A C 1 ATOM 3357 O O . ASP A 1 424 ? -16.259 -42.267 18.355 1.00 29.74 ? 451 ASP A O 1 ATOM 3358 C CB . ASP A 1 424 ? -18.042 -44.776 18.279 1.00 24.26 ? 451 ASP A CB 1 ATOM 3359 C CG . ASP A 1 424 ? -17.803 -45.463 16.934 1.00 30.70 ? 451 ASP A CG 1 ATOM 3360 O OD1 . ASP A 1 424 ? -17.598 -44.771 15.911 1.00 25.22 ? 451 ASP A OD1 1 ATOM 3361 O OD2 . ASP A 1 424 ? -17.822 -46.709 16.899 1.00 41.20 1 451 ASP A OD2 1 ATOM 3362 N N . LEU A 1 425 ? -17.255 -42.196 16.324 1.00 22.73 ? 452 LEU A N 1 ATOM 3363 C CA . LEU A 1 425 ? -16.134 -41.595 15.608 1.00 21.53 ? 452 LEU A CA 1 ATOM 3364 C C . LEU A 1 425 ? -14.960 -42.567 15.522 1.00 23.30 ? 452 LEU A C 1 ATOM 3365 O O . LEU A 1 425 ? -13.826 -42.176 15.246 1.00 18.41 ? 452 LEU A O 1 ATOM 3366 C CB . LEU A 1 425 ? -15.746 -40.249 16.215 1.00 17.72 ? 452 LEU A CB 1 ATOM 3367 C CG . LEU A 1 425 ? -16.933 -39.285 16.146 1.00 17.80 ? 452 LEU A CG 1 ATOM 3368 C CD1 . LEU A 1 425 ? -16.678 -37.995 16.899 1.00 16.10 ? 452 LEU A CD1 1 ATOM 3369 C CD2 . LEU A 1 425 ? -17.264 -38.995 14.690 1.00 19.91 ? 452 LEU A CD2 1 ATOM 3370 N N . GLN A 1 426 ? -15.275 -43.840 15.763 1.00 28.77 ? 453 GLN A N 1 ATOM 3371 C CA . GLN A 1 426 ? -14.389 -44.978 15.516 1.00 27.95 ? 453 GLN A CA 1 ATOM 3372 C C . GLN A 1 426 ? -13.034 -44.908 16.210 1.00 37.11 ? 453 GLN A C 1 ATOM 3373 O O . GLN A 1 426 ? -12.120 -45.650 15.850 1.00 42.29 ? 453 GLN A O 1 ATOM 3374 C CB . GLN A 1 426 ? -14.195 -45.188 14.008 1.00 25.88 ? 453 GLN A CB 1 ATOM 3375 C CG . GLN A 1 426 ? -15.504 -45.225 13.223 1.00 37.68 ? 453 GLN A CG 1 ATOM 3376 C CD . GLN A 1 426 ? -15.332 -45.703 11.789 1.00 35.57 ? 453 GLN A CD 1 ATOM 3377 O OE1 . GLN A 1 426 ? -14.837 -46.805 11.545 1.00 37.02 ? 453 GLN A OE1 1 ATOM 3378 N NE2 . GLN A 1 426 ? -15.752 -44.877 10.833 1.00 27.98 ? 453 GLN A NE2 1 ATOM 3379 N N . GLN A 1 427 ? -12.905 -44.039 17.210 1.00 37.84 ? 454 GLN A N 1 ATOM 3380 C CA . GLN A 1 427 ? -11.599 -43.803 17.823 1.00 39.63 ? 454 GLN A CA 1 ATOM 3381 C C . GLN A 1 427 ? -11.083 -44.971 18.645 1.00 41.03 ? 454 GLN A C 1 ATOM 3382 O O . GLN A 1 427 ? -11.726 -45.395 19.609 1.00 34.16 ? 454 GLN A O 1 ATOM 3383 C CB . GLN A 1 427 ? -11.582 -42.525 18.668 1.00 31.84 ? 454 GLN A CB 1 ATOM 3384 C CG . GLN A 1 427 ? -10.944 -41.333 17.963 1.00 36.02 ? 454 GLN A CG 1 ATOM 3385 C CD . GLN A 1 427 ? -9.547 -41.626 17.434 1.00 45.11 ? 454 GLN A CD 1 ATOM 3386 O OE1 . GLN A 1 427 ? -8.770 -42.352 18.060 1.00 42.70 ? 454 GLN A OE1 1 ATOM 3387 N NE2 . GLN A 1 427 ? -9.221 -41.056 16.274 1.00 37.16 ? 454 GLN A NE2 1 ATOM 3388 N N . PRO A 1 428 ? -9.914 -45.499 18.248 1.00 39.59 ? 455 PRO A N 1 ATOM 3389 C CA . PRO A 1 428 ? -9.161 -46.441 19.072 1.00 41.21 ? 455 PRO A CA 1 ATOM 3390 C C . PRO A 1 428 ? -8.806 -45.745 20.369 1.00 36.95 ? 455 PRO A C 1 ATOM 3391 O O . PRO A 1 428 ? -8.430 -44.575 20.346 1.00 34.75 ? 455 PRO A O 1 ATOM 3392 C CB . PRO A 1 428 ? -7.895 -46.690 18.247 1.00 45.53 ? 455 PRO A CB 1 ATOM 3393 C CG . PRO A 1 428 ? -7.805 -45.518 17.315 1.00 39.63 ? 455 PRO A CG 1 ATOM 3394 C CD . PRO A 1 428 ? -9.221 -45.206 16.984 1.00 34.37 ? 455 PRO A CD 1 ATOM 3395 N N . LEU A 1 429 ? -8.930 -46.453 21.482 1.00 35.38 ? 456 LEU A N 1 ATOM 3396 C CA . LEU A 1 429 ? -8.766 -45.838 22.790 1.00 34.62 ? 456 LEU A CA 1 ATOM 3397 C C . LEU A 1 429 ? -7.310 -45.513 23.104 1.00 36.12 ? 456 LEU A C 1 ATOM 3398 O O . LEU A 1 429 ? -7.026 -44.753 24.023 1.00 36.02 ? 456 LEU A O 1 ATOM 3399 C CB . LEU A 1 429 ? -9.365 -46.728 23.883 1.00 37.01 ? 456 LEU A CB 1 ATOM 3400 C CG . LEU A 1 429 ? -10.873 -46.999 23.806 1.00 47.40 ? 456 LEU A CG 1 ATOM 3401 C CD1 . LEU A 1 429 ? -11.207 -48.154 22.859 1.00 54.12 ? 456 LEU A CD1 1 ATOM 3402 C CD2 . LEU A 1 429 ? -11.459 -47.246 25.190 1.00 50.60 ? 456 LEU A CD2 1 ATOM 3403 N N . LEU A 1 430 ? -6.389 -46.078 22.332 1.00 34.54 ? 457 LEU A N 1 ATOM 3404 C CA . LEU A 1 430 ? -4.969 -45.887 22.600 1.00 30.49 ? 457 LEU A CA 1 ATOM 3405 C C . LEU A 1 430 ? -4.430 -44.543 22.105 1.00 31.73 ? 457 LEU A C 1 ATOM 3406 O O . LEU A 1 430 ? -3.482 -44.010 22.675 1.00 29.36 ? 457 LEU A O 1 ATOM 3407 C CB . LEU A 1 430 ? -4.155 -47.027 22.003 1.00 27.21 ? 457 LEU A CB 1 ATOM 3408 C CG . LEU A 1 430 ? -2.870 -47.325 22.768 1.00 27.54 ? 457 LEU A CG 1 ATOM 3409 C CD1 . LEU A 1 430 ? -3.135 -48.334 23.880 1.00 31.27 ? 457 LEU A CD1 1 ATOM 3410 C CD2 . LEU A 1 430 ? -1.795 -47.817 21.823 1.00 29.89 ? 457 LEU A CD2 1 ATOM 3411 N N . ASP A 1 431 ? -5.021 -44.009 21.038 1.00 33.06 ? 458 ASP A N 1 ATOM 3412 C CA . ASP A 1 431 ? -4.692 -42.664 20.569 1.00 30.54 ? 458 ASP A CA 1 ATOM 3413 C C . ASP A 1 431 ? -5.218 -41.630 21.550 1.00 34.55 ? 458 ASP A C 1 ATOM 3414 O O . ASP A 1 431 ? -4.711 -40.513 21.628 1.00 33.16 ? 458 ASP A O 1 ATOM 3415 C CB . ASP A 1 431 ? -5.315 -42.398 19.201 1.00 38.14 ? 458 ASP A CB 1 ATOM 3416 C CG . ASP A 1 431 ? -4.399 -42.767 18.059 1.00 35.73 ? 458 ASP A CG 1 ATOM 3417 O OD1 . ASP A 1 431 ? -3.355 -42.098 17.894 1.00 30.87 ? 458 ASP A OD1 1 ATOM 3418 O OD2 . ASP A 1 431 ? -4.737 -43.712 17.314 1.00 33.74 1 458 ASP A OD2 1 ATOM 3419 N N . ILE A 1 432 ? -6.256 -42.017 22.284 1.00 40.23 ? 459 ILE A N 1 ATOM 3420 C CA . ILE A 1 432 ? -6.864 -41.165 23.297 1.00 41.88 ? 459 ILE A CA 1 ATOM 3421 C C . ILE A 1 432 ? -5.934 -40.988 24.485 1.00 39.54 ? 459 ILE A C 1 ATOM 3422 O O . ILE A 1 432 ? -5.596 -39.866 24.856 1.00 41.15 ? 459 ILE A O 1 ATOM 3423 C CB . ILE A 1 432 ? -8.171 -41.777 23.824 1.00 38.48 ? 459 ILE A CB 1 ATOM 3424 C CG1 . ILE A 1 432 ? -9.111 -42.124 22.664 1.00 42.19 ? 459 ILE A CG1 1 ATOM 3425 C CG2 . ILE A 1 432 ? -8.821 -40.848 24.841 1.00 33.55 ? 459 ILE A CG2 1 ATOM 3426 C CD1 . ILE A 1 432 ? -9.354 -40.984 21.691 1.00 39.42 ? 459 ILE A CD1 1 ATOM 3427 N N . MET A 1 433 ? -5.533 -42.111 25.074 1.00 37.29 ? 460 MET A N 1 ATOM 3428 C CA . MET A 1 433 ? -4.655 -42.123 26.237 1.00 36.95 ? 460 MET A CA 1 ATOM 3429 C C . MET A 1 433 ? -3.349 -41.391 25.951 1.00 41.95 ? 460 MET A C 1 ATOM 3430 O O . MET A 1 433 ? -2.747 -40.805 26.852 1.00 42.87 ? 460 MET A O 1 ATOM 3431 C CB . MET A 1 433 ? -4.362 -43.565 26.659 1.00 38.93 ? 460 MET A CB 1 ATOM 3432 C CG . MET A 1 433 ? -5.602 -44.441 26.783 1.00 50.42 ? 460 MET A CG 1 ATOM 3433 S SD . MET A 1 433 ? -5.239 -46.214 26.757 1.00 80.06 ? 460 MET A SD 1 ATOM 3434 C CE . MET A 1 433 ? -6.882 -46.918 26.593 1.00 35.90 ? 460 MET A CE 1 ATOM 3435 N N . LEU A 1 434 ? -2.920 -41.420 24.692 1.00 42.13 ? 461 LEU A N 1 ATOM 3436 C CA . LEU A 1 434 ? -1.683 -40.755 24.291 1.00 44.43 ? 461 LEU A CA 1 ATOM 3437 C C . LEU A 1 434 ? -1.943 -39.356 23.735 1.00 46.46 ? 461 LEU A C 1 ATOM 3438 O O . LEU A 1 434 ? -1.212 -38.884 22.863 1.00 45.57 ? 461 LEU A O 1 ATOM 3439 C CB . LEU A 1 434 ? -0.910 -41.607 23.279 1.00 38.15 ? 461 LEU A CB 1 ATOM 3440 C CG . LEU A 1 434 ? -0.512 -43.001 23.775 1.00 39.09 ? 461 LEU A CG 1 ATOM 3441 C CD1 . LEU A 1 434 ? 0.255 -43.778 22.709 1.00 28.49 ? 461 LEU A CD1 1 ATOM 3442 C CD2 . LEU A 1 434 ? 0.298 -42.903 25.064 1.00 36.62 ? 461 LEU A CD2 1 ATOM 3443 N N . GLN A 1 435 ? -2.989 -38.713 24.257 1.00 45.86 ? 462 GLN A N 1 ATOM 3444 C CA . GLN A 1 435 ? -3.342 -37.318 23.966 1.00 44.57 ? 462 GLN A CA 1 ATOM 3445 C C . GLN A 1 435 ? -3.169 -36.885 22.513 1.00 53.69 ? 462 GLN A C 1 ATOM 3446 O O . GLN A 1 435 ? -2.743 -35.764 22.241 1.00 60.12 ? 462 GLN A O 1 ATOM 3447 C CB . GLN A 1 435 ? -2.595 -36.352 24.902 1.00 46.14 ? 462 GLN A CB 1 ATOM 3448 C CG . GLN A 1 435 ? -1.071 -36.336 24.751 1.00 56.99 ? 462 GLN A CG 1 ATOM 3449 C CD . GLN A 1 435 ? -0.382 -35.453 25.781 1.00 61.67 ? 462 GLN A CD 1 ATOM 3450 O OE1 . GLN A 1 435 ? -1.024 -34.932 26.694 1.00 68.53 ? 462 GLN A OE1 1 ATOM 3451 N NE2 . GLN A 1 435 ? 0.931 -35.283 25.638 1.00 46.87 ? 462 GLN A NE2 1 ATOM 3452 N N . THR A 1 436 ? -3.509 -37.770 21.582 1.00 55.87 ? 463 THR A N 1 ATOM 3453 C CA . THR A 1 436 ? -3.325 -37.473 20.164 1.00 59.17 ? 463 THR A CA 1 ATOM 3454 C C . THR A 1 436 ? -4.237 -36.333 19.701 1.00 53.74 ? 463 THR A C 1 ATOM 3455 O O . THR A 1 436 ? -5.455 -36.373 19.889 1.00 46.90 ? 463 THR A O 1 ATOM 3456 C CB . THR A 1 436 ? -3.523 -38.728 19.278 1.00 60.08 ? 463 THR A CB 1 ATOM 3457 O OG1 . THR A 1 436 ? -2.674 -39.789 19.742 1.00 44.82 ? 463 THR A OG1 1 ATOM 3458 C CG2 . THR A 1 436 ? -3.191 -38.418 17.820 1.00 59.57 ? 463 THR A CG2 1 ATOM 3459 N N . GLN A 1 437 ? -3.626 -35.311 19.111 1.00 56.26 ? 464 GLN A N 1 ATOM 3460 C CA . GLN A 1 437 ? -4.352 -34.152 18.604 1.00 66.01 ? 464 GLN A CA 1 ATOM 3461 C C . GLN A 1 437 ? -5.073 -34.488 17.300 1.00 63.92 ? 464 GLN A C 1 ATOM 3462 O O . GLN A 1 437 ? -4.534 -34.303 16.206 1.00 71.20 ? 464 GLN A O 1 ATOM 3463 C CB . GLN A 1 437 ? -3.389 -32.977 18.398 1.00 73.13 ? 464 GLN A CB 1 ATOM 3464 C CG . GLN A 1 437 ? -4.038 -31.702 17.872 1.00 75.25 ? 464 GLN A CG 1 ATOM 3465 C CD . GLN A 1 437 ? -3.066 -30.538 17.806 1.00 71.50 ? 464 GLN A CD 1 ATOM 3466 O OE1 . GLN A 1 437 ? -2.571 -30.070 18.833 1.00 70.17 ? 464 GLN A OE1 1 ATOM 3467 N NE2 . GLN A 1 437 ? -2.786 -30.065 16.595 1.00 62.94 ? 464 GLN A NE2 1 ATOM 3468 N N . ILE A 1 438 ? -6.296 -34.990 17.415 1.00 50.76 ? 465 ILE A N 1 ATOM 3469 C CA . ILE A 1 438 ? -7.036 -35.393 16.233 1.00 42.91 ? 465 ILE A CA 1 ATOM 3470 C C . ILE A 1 438 ? -8.462 -34.848 16.280 1.00 41.66 ? 465 ILE A C 1 ATOM 3471 O O . ILE A 1 438 ? -9.065 -34.744 17.349 1.00 38.98 ? 465 ILE A O 1 ATOM 3472 C CB . ILE A 1 438 ? -7.002 -36.931 16.051 1.00 40.95 ? 465 ILE A CB 1 ATOM 3473 C CG1 . ILE A 1 438 ? -7.501 -37.318 14.659 1.00 43.89 ? 465 ILE A CG1 1 ATOM 3474 C CG2 . ILE A 1 438 ? -7.764 -37.638 17.166 1.00 32.53 ? 465 ILE A CG2 1 ATOM 3475 C CD1 . ILE A 1 438 ? -6.712 -36.674 13.540 1.00 43.38 ? 465 ILE A CD1 1 ATOM 3476 N N . ASN A 1 439 ? -8.988 -34.479 15.117 1.00 39.29 ? 466 ASN A N 1 ATOM 3477 C CA . ASN A 1 439 ? -10.284 -33.815 15.046 1.00 33.45 ? 466 ASN A CA 1 ATOM 3478 C C . ASN A 1 439 ? -11.454 -34.691 14.611 1.00 34.18 ? 466 ASN A C 1 ATOM 3479 O O . ASN A 1 439 ? -11.317 -35.582 13.761 1.00 28.01 ? 466 ASN A O 1 ATOM 3480 C CB . ASN A 1 439 ? -10.203 -32.600 14.122 1.00 33.45 ? 466 ASN A CB 1 ATOM 3481 C CG . ASN A 1 439 ? -9.362 -31.490 14.697 1.00 35.26 ? 466 ASN A CG 1 ATOM 3482 O OD1 . ASN A 1 439 ? -9.352 -31.268 15.908 1.00 33.74 ? 466 ASN A OD1 1 ATOM 3483 N ND2 . ASN A 1 439 ? -8.648 -30.779 13.831 1.00 39.26 ? 466 ASN A ND2 1 ATOM 3484 N N . SER A 1 440 ? -12.611 -34.414 15.205 1.00 31.66 ? 467 SER A N 1 ATOM 3485 C CA . SER A 1 440 ? -13.876 -34.962 14.740 1.00 31.16 ? 467 SER A CA 1 ATOM 3486 C C . SER A 1 440 ? -14.177 -34.325 13.390 1.00 26.61 ? 467 SER A C 1 ATOM 3487 O O . SER A 1 440 ? -13.662 -33.244 13.093 1.00 24.21 ? 467 SER A O 1 ATOM 3488 C CB . SER A 1 440 ? -14.990 -34.628 15.735 1.00 27.08 ? 467 SER A CB 1 ATOM 3489 O OG . SER A 1 440 ? -15.269 -33.238 15.736 1.00 28.05 ? 467 SER A OG 1 ATOM 3490 N N . PRO A 1 441 ? -15.021 -34.978 12.569 1.00 25.29 ? 468 PRO A N 1 ATOM 3491 C CA . PRO A 1 441 ? -15.334 -34.464 11.228 1.00 25.07 ? 468 PRO A CA 1 ATOM 3492 C C . PRO A 1 441 ? -16.030 -33.106 11.268 1.00 23.35 ? 468 PRO A C 1 ATOM 3493 O O . PRO A 1 441 ? -16.319 -32.519 10.217 1.00 19.73 ? 468 PRO A O 1 ATOM 3494 C CB . PRO A 1 441 ? -16.286 -35.523 10.657 1.00 20.08 ? 468 PRO A CB 1 ATOM 3495 C CG . PRO A 1 441 ? -16.001 -36.758 11.439 1.00 22.15 ? 468 PRO A CG 1 ATOM 3496 C CD . PRO A 1 441 ? -15.659 -36.283 12.817 1.00 24.73 ? 468 PRO A CD 1 ATOM 3497 N N . PHE A 1 442 ? -16.284 -32.616 12.477 1.00 20.23 ? 469 PHE A N 1 ATOM 3498 C CA . PHE A 1 442 ? -16.971 -31.351 12.666 1.00 22.73 ? 469 PHE A CA 1 ATOM 3499 C C . PHE A 1 442 ? -15.943 -30.226 12.734 1.00 26.20 ? 469 PHE A C 1 ATOM 3500 O O . PHE A 1 442 ? -16.293 -29.062 12.929 1.00 28.91 ? 469 PHE A O 1 ATOM 3501 C CB . PHE A 1 442 ? -17.818 -31.383 13.944 1.00 21.21 ? 469 PHE A CB 1 ATOM 3502 C CG . PHE A 1 442 ? -18.705 -32.603 14.071 1.00 24.49 ? 469 PHE A CG 1 ATOM 3503 C CD1 . PHE A 1 442 ? -19.127 -33.308 12.954 1.00 24.33 ? 469 PHE A CD1 1 ATOM 3504 C CD2 . PHE A 1 442 ? -19.124 -33.038 15.318 1.00 22.53 ? 469 PHE A CD2 1 ATOM 3505 C CE1 . PHE A 1 442 ? -19.927 -34.422 13.083 1.00 19.90 ? 469 PHE A CE1 1 ATOM 3506 C CE2 . PHE A 1 442 ? -19.930 -34.151 15.448 1.00 17.25 ? 469 PHE A CE2 1 ATOM 3507 C CZ . PHE A 1 442 ? -20.324 -34.843 14.331 1.00 16.95 ? 469 PHE A CZ 1 ATOM 3508 N N . GLY A 1 443 ? -14.676 -30.593 12.554 1.00 26.99 ? 470 GLY A N 1 ATOM 3509 C CA . GLY A 1 443 ? -13.549 -29.686 12.697 1.00 22.28 ? 470 GLY A CA 1 ATOM 3510 C C . GLY A 1 443 ? -13.634 -28.341 11.997 1.00 26.78 ? 470 GLY A C 1 ATOM 3511 O O . GLY A 1 443 ? -13.280 -27.318 12.580 1.00 32.31 ? 470 GLY A O 1 ATOM 3512 N N . TYR A 1 444 ? -14.106 -28.330 10.754 1.00 27.70 ? 471 TYR A N 1 ATOM 3513 C CA . TYR A 1 444 ? -14.108 -27.107 9.948 1.00 29.69 ? 471 TYR A CA 1 ATOM 3514 C C . TYR A 1 444 ? -15.129 -26.069 10.403 1.00 28.88 ? 471 TYR A C 1 ATOM 3515 O O . TYR A 1 444 ? -15.080 -24.914 9.979 1.00 32.43 ? 471 TYR A O 1 ATOM 3516 C CB . TYR A 1 444 ? -14.374 -27.432 8.480 1.00 28.42 ? 471 TYR A CB 1 ATOM 3517 C CG . TYR A 1 444 ? -13.635 -28.635 7.966 1.00 26.50 ? 471 TYR A CG 1 ATOM 3518 C CD1 . TYR A 1 444 ? -12.324 -28.534 7.529 1.00 29.38 ? 471 TYR A CD1 1 ATOM 3519 C CD2 . TYR A 1 444 ? -14.254 -29.874 7.907 1.00 29.42 ? 471 TYR A CD2 1 ATOM 3520 C CE1 . TYR A 1 444 ? -11.646 -29.637 7.053 1.00 29.43 ? 471 TYR A CE1 1 ATOM 3521 C CE2 . TYR A 1 444 ? -13.586 -30.981 7.431 1.00 33.61 ? 471 TYR A CE2 1 ATOM 3522 C CZ . TYR A 1 444 ? -12.283 -30.857 7.007 1.00 28.92 ? 471 TYR A CZ 1 ATOM 3523 O OH . TYR A 1 444 ? -11.622 -31.961 6.533 1.00 33.36 ? 471 TYR A OH 1 ATOM 3524 N N . MET A 1 445 ? -16.065 -26.477 11.247 1.00 22.90 ? 472 MET A N 1 ATOM 3525 C CA . MET A 1 445 ? -17.131 -25.576 11.649 1.00 24.78 ? 472 MET A CA 1 ATOM 3526 C C . MET A 1 445 ? -16.766 -24.779 12.890 1.00 27.93 ? 472 MET A C 1 ATOM 3527 O O . MET A 1 445 ? -17.100 -25.151 14.011 1.00 26.90 ? 472 MET A O 1 ATOM 3528 C CB . MET A 1 445 ? -18.444 -26.336 11.813 1.00 33.50 ? 472 MET A CB 1 ATOM 3529 C CG . MET A 1 445 ? -19.026 -26.780 10.474 1.00 34.05 ? 472 MET A CG 1 ATOM 3530 S SD . MET A 1 445 ? -20.518 -27.762 10.619 1.00 20.99 ? 472 MET A SD 1 ATOM 3531 C CE . MET A 1 445 ? -19.919 -29.102 11.647 1.00 19.56 ? 472 MET A CE 1 ATOM 3532 N N . HIS A 1 446 ? -16.068 -23.674 12.647 1.00 38.76 ? 473 HIS A N 1 ATOM 3533 C CA . HIS A 1 446 ? -15.550 -22.772 13.672 1.00 34.93 ? 473 HIS A CA 1 ATOM 3534 C C . HIS A 1 446 ? -16.665 -21.977 14.332 1.00 32.58 ? 473 HIS A C 1 ATOM 3535 O O . HIS A 1 446 ? -16.663 -21.763 15.547 1.00 29.49 ? 473 HIS A O 1 ATOM 3536 C CB . HIS A 1 446 ? -14.558 -21.806 13.019 1.00 32.48 ? 473 HIS A CB 1 ATOM 3537 C CG . HIS A 1 446 ? -14.696 -21.727 11.528 1.00 47.02 ? 473 HIS A CG 1 ATOM 3538 N ND1 . HIS A 1 446 ? -13.689 -22.103 10.664 1.00 52.01 ? 473 HIS A ND1 1 ATOM 3539 C CD2 . HIS A 1 446 ? -15.736 -21.343 10.747 1.00 49.71 ? 473 HIS A CD2 1 ATOM 3540 C CE1 . HIS A 1 446 ? -14.097 -21.942 9.417 1.00 52.78 ? 473 HIS A CE1 1 ATOM 3541 N NE2 . HIS A 1 446 ? -15.336 -21.483 9.439 1.00 51.30 ? 473 HIS A NE2 1 ATOM 3542 N N . GLY A 1 447 ? -17.616 -21.539 13.513 1.00 39.57 ? 474 GLY A N 1 ATOM 3543 C CA . GLY A 1 447 ? -18.711 -20.710 13.976 1.00 36.06 ? 474 GLY A CA 1 ATOM 3544 C C . GLY A 1 447 ? -19.903 -21.498 14.481 1.00 27.31 ? 474 GLY A C 1 ATOM 3545 O O . GLY A 1 447 ? -20.949 -20.918 14.760 1.00 25.64 ? 474 GLY A O 1 ATOM 3546 N N . LEU A 1 448 ? -19.743 -22.813 14.602 1.00 22.39 ? 475 LEU A N 1 ATOM 3547 C CA . LEU A 1 448 ? -20.809 -23.680 15.093 1.00 20.34 ? 475 LEU A CA 1 ATOM 3548 C C . LEU A 1 448 ? -21.219 -23.298 16.513 1.00 23.60 ? 475 LEU A C 1 ATOM 3549 O O . LEU A 1 448 ? -20.384 -22.902 17.325 1.00 28.10 ? 475 LEU A O 1 ATOM 3550 C CB . LEU A 1 448 ? -20.365 -25.140 15.055 1.00 24.89 ? 475 LEU A CB 1 ATOM 3551 C CG . LEU A 1 448 ? -21.459 -26.204 15.165 1.00 25.15 ? 475 LEU A CG 1 ATOM 3552 C CD1 . LEU A 1 448 ? -22.119 -26.448 13.811 1.00 19.85 ? 475 LEU A CD1 1 ATOM 3553 C CD2 . LEU A 1 448 ? -20.904 -27.499 15.745 1.00 20.91 ? 475 LEU A CD2 1 ATOM 3554 N N . LEU A 1 449 ? -22.509 -23.423 16.805 1.00 23.24 ? 476 LEU A N 1 ATOM 3555 C CA . LEU A 1 449 ? -23.062 -22.978 18.081 1.00 25.75 ? 476 LEU A CA 1 ATOM 3556 C C . LEU A 1 449 ? -23.595 -24.139 18.913 1.00 27.03 ? 476 LEU A C 1 ATOM 3557 O O . LEU A 1 449 ? -23.472 -24.147 20.142 1.00 24.38 ? 476 LEU A O 1 ATOM 3558 C CB . LEU A 1 449 ? -24.192 -21.979 17.833 1.00 26.09 ? 476 LEU A CB 1 ATOM 3559 C CG . LEU A 1 449 ? -23.793 -20.686 17.130 1.00 25.29 ? 476 LEU A CG 1 ATOM 3560 C CD1 . LEU A 1 449 ? -25.011 -19.981 16.559 1.00 18.43 ? 476 LEU A CD1 1 ATOM 3561 C CD2 . LEU A 1 449 ? -23.056 -19.790 18.109 1.00 34.58 ? 476 LEU A CD2 1 ATOM 3562 N N . THR A 1 450 ? -24.198 -25.113 18.236 1.00 22.91 ? 477 THR A N 1 ATOM 3563 C CA . THR A 1 450 ? -24.825 -26.238 18.916 1.00 20.89 ? 477 THR A CA 1 ATOM 3564 C C . THR A 1 450 ? -24.351 -27.589 18.398 1.00 21.96 ? 477 THR A C 1 ATOM 3565 O O . THR A 1 450 ? -24.469 -27.889 17.211 1.00 20.98 ? 477 THR A O 1 ATOM 3566 C CB . THR A 1 450 ? -26.351 -26.189 18.784 1.00 19.16 ? 477 THR A CB 1 ATOM 3567 O OG1 . THR A 1 450 ? -26.845 -24.987 19.384 1.00 24.96 ? 477 THR A OG1 1 ATOM 3568 C CG2 . THR A 1 450 ? -26.977 -27.391 19.469 1.00 16.34 ? 477 THR A CG2 1 ATOM 3569 N N . LEU A 1 451 ? -23.815 -28.399 19.304 1.00 24.89 ? 478 LEU A N 1 ATOM 3570 C CA . LEU A 1 451 ? -23.480 -29.783 19.008 1.00 18.51 ? 478 LEU A CA 1 ATOM 3571 C C . LEU A 1 451 ? -24.264 -30.666 19.969 1.00 17.86 ? 478 LEU A C 1 ATOM 3572 O O . LEU A 1 451 ? -24.266 -30.428 21.176 1.00 17.30 ? 478 LEU A O 1 ATOM 3573 C CB . LEU A 1 451 ? -21.986 -30.021 19.187 1.00 19.47 ? 478 LEU A CB 1 ATOM 3574 C CG . LEU A 1 451 ? -21.299 -30.853 18.106 1.00 20.72 ? 478 LEU A CG 1 ATOM 3575 C CD1 . LEU A 1 451 ? -19.984 -31.413 18.628 1.00 18.69 ? 478 LEU A CD1 1 ATOM 3576 C CD2 . LEU A 1 451 ? -22.207 -31.963 17.611 1.00 21.03 ? 478 LEU A CD2 1 ATOM 3577 N N . ASN A 1 452 ? -24.940 -31.678 19.439 1.00 17.01 ? 479 ASN A N 1 ATOM 3578 C CA . ASN A 1 452 ? -25.785 -32.512 20.277 1.00 14.72 ? 479 ASN A CA 1 ATOM 3579 C C . ASN A 1 452 ? -25.604 -33.993 20.033 1.00 16.32 ? 479 ASN A C 1 ATOM 3580 O O . ASN A 1 452 ? -26.368 -34.598 19.288 1.00 20.23 ? 479 ASN A O 1 ATOM 3581 C CB . ASN A 1 452 ? -27.250 -32.149 20.093 1.00 11.57 ? 479 ASN A CB 1 ATOM 3582 C CG . ASN A 1 452 ? -28.109 -32.663 21.224 1.00 18.32 ? 479 ASN A CG 1 ATOM 3583 O OD1 . ASN A 1 452 ? -27.924 -33.783 21.705 1.00 17.22 ? 479 ASN A OD1 1 ATOM 3584 N ND2 . ASN A 1 452 ? -29.040 -31.837 21.676 1.00 26.39 ? 479 ASN A ND2 1 ATOM 3585 N N . LEU A 1 453 ? -24.619 -34.579 20.701 1.00 16.39 ? 480 LEU A N 1 ATOM 3586 C CA . LEU A 1 453 ? -24.285 -35.980 20.510 1.00 14.18 ? 480 LEU A CA 1 ATOM 3587 C C . LEU A 1 453 ? -24.805 -36.847 21.655 1.00 15.53 ? 480 LEU A C 1 ATOM 3588 O O . LEU A 1 453 ? -24.268 -37.915 21.932 1.00 17.43 ? 480 LEU A O 1 ATOM 3589 C CB . LEU A 1 453 ? -22.776 -36.113 20.375 1.00 14.22 ? 480 LEU A CB 1 ATOM 3590 C CG . LEU A 1 453 ? -22.220 -35.135 19.343 1.00 12.69 ? 480 LEU A CG 1 ATOM 3591 C CD1 . LEU A 1 453 ? -20.820 -34.709 19.703 1.00 12.47 ? 480 LEU A CD1 1 ATOM 3592 C CD2 . LEU A 1 453 ? -22.238 -35.773 17.976 1.00 14.77 ? 480 LEU A CD2 1 ATOM 3593 N N . ARG A 1 454 ? -25.855 -36.372 22.312 1.00 15.99 ? 481 ARG A N 1 ATOM 3594 C CA . ARG A 1 454 ? -26.510 -37.110 23.383 1.00 16.97 ? 481 ARG A CA 1 ATOM 3595 C C . ARG A 1 454 ? -26.872 -38.523 22.930 1.00 19.24 ? 481 ARG A C 1 ATOM 3596 O O . ARG A 1 454 ? -27.178 -38.737 21.758 1.00 21.06 ? 481 ARG A O 1 ATOM 3597 C CB . ARG A 1 454 ? -27.768 -36.354 23.820 1.00 16.30 ? 481 ARG A CB 1 ATOM 3598 C CG . ARG A 1 454 ? -28.585 -37.036 24.897 1.00 15.77 ? 481 ARG A CG 1 ATOM 3599 C CD . ARG A 1 454 ? -29.721 -36.146 25.362 1.00 12.98 ? 481 ARG A CD 1 ATOM 3600 N NE . ARG A 1 454 ? -29.244 -34.988 26.110 1.00 12.50 ? 481 ARG A NE 1 ATOM 3601 C CZ . ARG A 1 454 ? -29.502 -34.771 27.397 1.00 15.18 ? 481 ARG A CZ 1 ATOM 3602 N NH1 . ARG A 1 454 ? -30.239 -35.634 28.084 1.00 15.82 1 481 ARG A NH1 1 ATOM 3603 N NH2 . ARG A 1 454 ? -29.022 -33.690 27.997 1.00 15.30 ? 481 ARG A NH2 1 ATOM 3604 N N . ASN A 1 455 ? -26.813 -39.482 23.852 1.00 18.24 ? 482 ASN A N 1 ATOM 3605 C CA . ASN A 1 455 ? -27.207 -40.865 23.570 1.00 19.89 ? 482 ASN A CA 1 ATOM 3606 C C . ASN A 1 455 ? -26.408 -41.506 22.430 1.00 20.28 ? 482 ASN A C 1 ATOM 3607 O O . ASN A 1 455 ? -26.911 -42.374 21.725 1.00 21.93 ? 482 ASN A O 1 ATOM 3608 C CB . ASN A 1 455 ? -28.711 -40.943 23.272 1.00 24.86 ? 482 ASN A CB 1 ATOM 3609 C CG . ASN A 1 455 ? -29.310 -42.317 23.557 1.00 27.42 ? 482 ASN A CG 1 ATOM 3610 O OD1 . ASN A 1 455 ? -28.591 -43.289 23.785 1.00 27.15 ? 482 ASN A OD1 1 ATOM 3611 N ND2 . ASN A 1 455 ? -30.646 -42.390 23.545 1.00 28.22 ? 482 ASN A ND2 1 ATOM 3612 N N . ASN A 1 456 ? -25.170 -41.064 22.241 1.00 20.02 ? 483 ASN A N 1 ATOM 3613 C CA . ASN A 1 456 ? -24.259 -41.751 21.335 1.00 20.12 ? 483 ASN A CA 1 ATOM 3614 C C . ASN A 1 456 ? -23.213 -42.564 22.106 1.00 22.01 ? 483 ASN A C 1 ATOM 3615 O O . ASN A 1 456 ? -23.428 -42.938 23.268 1.00 18.05 ? 483 ASN A O 1 ATOM 3616 C CB . ASN A 1 456 ? -23.566 -40.763 20.396 1.00 21.16 ? 483 ASN A CB 1 ATOM 3617 C CG . ASN A 1 456 ? -24.474 -40.273 19.283 1.00 18.20 ? 483 ASN A CG 1 ATOM 3618 O OD1 . ASN A 1 456 ? -24.689 -40.969 18.292 1.00 16.70 ? 483 ASN A OD1 1 ATOM 3619 N ND2 . ASN A 1 456 ? -24.990 -39.058 19.429 1.00 15.53 ? 483 ASN A ND2 1 ATOM 3620 N N . SER A 1 457 ? -22.087 -42.826 21.440 1.00 21.91 ? 484 SER A N 1 ATOM 3621 C CA . SER A 1 457 ? -20.982 -43.607 22.005 1.00 18.70 ? 484 SER A CA 1 ATOM 3622 C C . SER A 1 457 ? -19.624 -42.897 21.855 1.00 21.84 ? 484 SER A C 1 ATOM 3623 O O . SER A 1 457 ? -18.610 -43.524 21.532 1.00 24.83 ? 484 SER A O 1 ATOM 3624 C CB . SER A 1 457 ? -20.932 -45.025 21.412 1.00 17.23 ? 484 SER A CB 1 ATOM 3625 O OG . SER A 1 457 ? -21.926 -45.837 22.011 1.00 22.29 ? 484 SER A OG 1 ATOM 3626 N N . ILE A 1 458 ? -19.607 -41.587 22.088 1.00 21.23 ? 485 ILE A N 1 ATOM 3627 C CA . ILE A 1 458 ? -18.359 -40.839 22.050 1.00 19.88 ? 485 ILE A CA 1 ATOM 3628 C C . ILE A 1 458 ? -17.567 -41.364 23.228 1.00 22.03 ? 485 ILE A C 1 ATOM 3629 O O . ILE A 1 458 ? -18.166 -41.676 24.259 1.00 20.22 ? 485 ILE A O 1 ATOM 3630 C CB . ILE A 1 458 ? -18.595 -39.331 22.229 1.00 17.60 ? 485 ILE A CB 1 ATOM 3631 C CG1 . ILE A 1 458 ? -19.517 -38.804 21.136 1.00 19.42 ? 485 ILE A CG1 1 ATOM 3632 C CG2 . ILE A 1 458 ? -17.281 -38.573 22.210 1.00 14.70 ? 485 ILE A CG2 1 ATOM 3633 C CD1 . ILE A 1 458 ? -18.868 -38.716 19.772 1.00 19.16 ? 485 ILE A CD1 1 ATOM 3634 N N . ILE A 1 459 ? -16.247 -41.498 23.071 1.00 23.74 ? 486 ILE A N 1 ATOM 3635 C CA . ILE A 1 459 ? -15.366 -41.956 24.152 1.00 20.01 ? 486 ILE A CA 1 ATOM 3636 C C . ILE A 1 459 ? -14.203 -41.010 24.446 1.00 20.39 ? 486 ILE A C 1 ATOM 3637 O O . ILE A 1 459 ? -13.187 -41.429 25.014 1.00 27.60 ? 486 ILE A O 1 ATOM 3638 C CB . ILE A 1 459 ? -14.766 -43.322 23.832 1.00 16.01 ? 486 ILE A CB 1 ATOM 3639 C CG1 . ILE A 1 459 ? -13.944 -43.248 22.547 1.00 17.29 ? 486 ILE A CG1 1 ATOM 3640 C CG2 . ILE A 1 459 ? -15.875 -44.336 23.693 1.00 26.29 ? 486 ILE A CG2 1 ATOM 3641 C CD1 . ILE A 1 459 ? -12.898 -44.327 22.430 1.00 25.12 ? 486 ILE A CD1 1 ATOM 3642 N N . PHE A 1 460 ? -14.365 -39.738 24.087 1.00 17.25 ? 487 PHE A N 1 ATOM 3643 C CA . PHE A 1 460 ? -13.278 -38.760 24.151 1.00 15.90 ? 487 PHE A CA 1 ATOM 3644 C C . PHE A 1 460 ? -13.757 -37.361 23.785 1.00 13.95 ? 487 PHE A C 1 ATOM 3645 O O . PHE A 1 460 ? -14.493 -37.194 22.830 1.00 16.26 ? 487 PHE A O 1 ATOM 3646 C CB . PHE A 1 460 ? -12.159 -39.179 23.193 1.00 17.64 ? 487 PHE A CB 1 ATOM 3647 C CG . PHE A 1 460 ? -11.038 -38.185 23.082 1.00 20.49 ? 487 PHE A CG 1 ATOM 3648 C CD1 . PHE A 1 460 ? -10.361 -37.749 24.211 1.00 28.27 ? 487 PHE A CD1 1 ATOM 3649 C CD2 . PHE A 1 460 ? -10.640 -37.711 21.843 1.00 19.83 ? 487 PHE A CD2 1 ATOM 3650 C CE1 . PHE A 1 460 ? -9.320 -36.843 24.104 1.00 31.67 ? 487 PHE A CE1 1 ATOM 3651 C CE2 . PHE A 1 460 ? -9.601 -36.805 21.726 1.00 22.56 ? 487 PHE A CE2 1 ATOM 3652 C CZ . PHE A 1 460 ? -8.939 -36.371 22.858 1.00 31.66 ? 487 PHE A CZ 1 ATOM 3653 N N . VAL A 1 461 ? -13.332 -36.351 24.536 1.00 16.60 ? 488 VAL A N 1 ATOM 3654 C CA . VAL A 1 461 ? -13.621 -34.963 24.173 1.00 15.51 ? 488 VAL A CA 1 ATOM 3655 C C . VAL A 1 461 ? -12.650 -34.498 23.087 1.00 18.00 ? 488 VAL A C 1 ATOM 3656 O O . VAL A 1 461 ? -11.502 -34.171 23.378 1.00 27.91 ? 488 VAL A O 1 ATOM 3657 C CB . VAL A 1 461 ? -13.510 -34.032 25.393 1.00 12.07 ? 488 VAL A CB 1 ATOM 3658 C CG1 . VAL A 1 461 ? -13.796 -32.597 24.997 1.00 12.12 ? 488 VAL A CG1 1 ATOM 3659 C CG2 . VAL A 1 461 ? -14.452 -34.485 26.489 1.00 13.07 ? 488 VAL A CG2 1 ATOM 3660 N N . TYR A 1 462 ? -13.100 -34.476 21.836 1.00 14.78 ? 489 TYR A N 1 ATOM 3661 C CA . TYR A 1 462 ? -12.183 -34.251 20.714 1.00 20.79 ? 489 TYR A CA 1 ATOM 3662 C C . TYR A 1 462 ? -11.553 -32.863 20.681 1.00 21.63 ? 489 TYR A C 1 ATOM 3663 O O . TYR A 1 462 ? -12.089 -31.907 21.238 1.00 18.79 ? 489 TYR A O 1 ATOM 3664 C CB . TYR A 1 462 ? -12.835 -34.602 19.363 1.00 22.74 ? 489 TYR A CB 1 ATOM 3665 C CG . TYR A 1 462 ? -13.042 -36.089 19.184 1.00 18.17 ? 489 TYR A CG 1 ATOM 3666 C CD1 . TYR A 1 462 ? -13.986 -36.760 19.940 1.00 14.42 ? 489 TYR A CD1 1 ATOM 3667 C CD2 . TYR A 1 462 ? -12.284 -36.823 18.277 1.00 16.15 ? 489 TYR A CD2 1 ATOM 3668 C CE1 . TYR A 1 462 ? -14.179 -38.110 19.810 1.00 15.64 ? 489 TYR A CE1 1 ATOM 3669 C CE2 . TYR A 1 462 ? -12.473 -38.189 18.138 1.00 14.44 ? 489 TYR A CE2 1 ATOM 3670 C CZ . TYR A 1 462 ? -13.426 -38.823 18.912 1.00 15.90 ? 489 TYR A CZ 1 ATOM 3671 O OH . TYR A 1 462 ? -13.656 -40.174 18.808 1.00 18.92 ? 489 TYR A OH 1 ATOM 3672 N N . ASN A 1 463 ? -10.402 -32.782 20.023 1.00 29.04 ? 490 ASN A N 1 ATOM 3673 C CA . ASN A 1 463 ? -9.606 -31.563 19.951 1.00 34.39 ? 490 ASN A CA 1 ATOM 3674 C C . ASN A 1 463 ? -10.388 -30.372 19.420 1.00 32.33 ? 490 ASN A C 1 ATOM 3675 O O . ASN A 1 463 ? -10.334 -29.280 19.987 1.00 35.06 ? 490 ASN A O 1 ATOM 3676 C CB . ASN A 1 463 ? -8.366 -31.800 19.077 1.00 42.45 ? 490 ASN A CB 1 ATOM 3677 C CG . ASN A 1 463 ? -7.457 -30.580 18.996 1.00 50.09 ? 490 ASN A CG 1 ATOM 3678 O OD1 . ASN A 1 463 ? -6.538 -30.421 19.801 1.00 54.55 ? 490 ASN A OD1 1 ATOM 3679 N ND2 . ASN A 1 463 ? -7.706 -29.720 18.015 1.00 43.93 ? 490 ASN A ND2 1 ATOM 3680 N N . ASP A 1 464 ? -11.123 -30.595 18.337 1.00 34.23 ? 491 ASP A N 1 ATOM 3681 C CA . ASP A 1 464 ? -11.793 -29.514 17.620 1.00 33.17 ? 491 ASP A CA 1 ATOM 3682 C C . ASP A 1 464 ? -12.861 -28.759 18.420 1.00 27.22 ? 491 ASP A C 1 ATOM 3683 O O . ASP A 1 464 ? -13.114 -27.586 18.155 1.00 27.39 ? 491 ASP A O 1 ATOM 3684 C CB . ASP A 1 464 ? -12.361 -30.013 16.280 1.00 32.79 ? 491 ASP A CB 1 ATOM 3685 C CG . ASP A 1 464 ? -12.953 -31.417 16.369 1.00 31.97 ? 491 ASP A CG 1 ATOM 3686 O OD1 . ASP A 1 464 ? -12.563 -32.183 17.277 1.00 32.58 ? 491 ASP A OD1 1 ATOM 3687 O OD2 . ASP A 1 464 ? -13.799 -31.762 15.515 1.00 27.37 1 491 ASP A OD2 1 ATOM 3688 N N . TRP A 1 465 ? -13.467 -29.417 19.405 1.00 25.91 ? 492 TRP A N 1 ATOM 3689 C CA . TRP A 1 465 ? -14.586 -28.819 20.140 1.00 27.31 ? 492 TRP A CA 1 ATOM 3690 C C . TRP A 1 465 ? -14.114 -27.878 21.242 1.00 25.80 ? 492 TRP A C 1 ATOM 3691 O O . TRP A 1 465 ? -14.914 -27.175 21.855 1.00 25.03 ? 492 TRP A O 1 ATOM 3692 C CB . TRP A 1 465 ? -15.501 -29.895 20.747 1.00 23.06 ? 492 TRP A CB 1 ATOM 3693 C CG . TRP A 1 465 ? -15.800 -31.058 19.836 1.00 20.86 ? 492 TRP A CG 1 ATOM 3694 C CD1 . TRP A 1 465 ? -15.716 -31.089 18.468 1.00 17.79 ? 492 TRP A CD1 1 ATOM 3695 C CD2 . TRP A 1 465 ? -16.213 -32.365 20.239 1.00 14.20 ? 492 TRP A CD2 1 ATOM 3696 N NE1 . TRP A 1 465 ? -16.051 -32.334 18.003 1.00 14.83 ? 492 TRP A NE1 1 ATOM 3697 C CE2 . TRP A 1 465 ? -16.361 -33.136 19.069 1.00 15.21 ? 492 TRP A CE2 1 ATOM 3698 C CE3 . TRP A 1 465 ? -16.470 -32.959 21.477 1.00 11.11 ? 492 TRP A CE3 1 ATOM 3699 C CZ2 . TRP A 1 465 ? -16.756 -34.469 19.103 1.00 15.42 ? 492 TRP A CZ2 1 ATOM 3700 C CZ3 . TRP A 1 465 ? -16.859 -34.280 21.509 1.00 11.79 ? 492 TRP A CZ3 1 ATOM 3701 C CH2 . TRP A 1 465 ? -16.999 -35.023 20.331 1.00 15.06 ? 492 TRP A CH2 1 ATOM 3702 N N . LYS A 1 466 ? -12.812 -27.875 21.495 1.00 31.46 ? 493 LYS A N 1 ATOM 3703 C CA . LYS A 1 466 ? -12.253 -27.048 22.551 1.00 30.52 ? 493 LYS A CA 1 ATOM 3704 C C . LYS A 1 466 ? -11.555 -25.838 21.964 1.00 31.76 ? 493 LYS A C 1 ATOM 3705 O O . LYS A 1 466 ? -11.684 -24.730 22.475 1.00 36.82 ? 493 LYS A O 1 ATOM 3706 C CB . LYS A 1 466 ? -11.263 -27.853 23.396 1.00 31.41 ? 493 LYS A CB 1 ATOM 3707 C CG . LYS A 1 466 ? -11.863 -29.072 24.089 1.00 32.77 ? 493 LYS A CG 1 ATOM 3708 C CD . LYS A 1 466 ? -10.836 -29.801 24.952 1.00 36.91 ? 493 LYS A CD 1 ATOM 3709 C CE . LYS A 1 466 ? -9.638 -30.261 24.124 1.00 40.46 ? 493 LYS A CE 1 ATOM 3710 N NZ . LYS A 1 466 ? -8.622 -30.990 24.934 1.00 36.19 1 493 LYS A NZ 1 ATOM 3711 N N . ASN A 1 467 ? -10.826 -26.054 20.875 1.00 33.90 ? 494 ASN A N 1 ATOM 3712 C CA . ASN A 1 467 ? -9.928 -25.032 20.348 1.00 38.83 ? 494 ASN A CA 1 ATOM 3713 C C . ASN A 1 467 ? -10.325 -24.446 18.995 1.00 38.12 ? 494 ASN A C 1 ATOM 3714 O O . ASN A 1 467 ? -9.962 -23.312 18.684 1.00 43.94 ? 494 ASN A O 1 ATOM 3715 C CB . ASN A 1 467 ? -8.494 -25.570 20.290 1.00 43.10 ? 494 ASN A CB 1 ATOM 3716 C CG . ASN A 1 467 ? -7.966 -25.970 21.657 1.00 40.18 ? 494 ASN A CG 1 ATOM 3717 O OD1 . ASN A 1 467 ? -8.115 -25.236 22.635 1.00 33.90 ? 494 ASN A OD1 1 ATOM 3718 N ND2 . ASN A 1 467 ? -7.352 -27.146 21.733 1.00 38.49 ? 494 ASN A ND2 1 ATOM 3719 N N . THR A 1 468 ? -11.060 -25.210 18.190 1.00 34.63 ? 495 THR A N 1 ATOM 3720 C CA . THR A 1 468 ? -11.487 -24.717 16.879 1.00 39.84 ? 495 THR A CA 1 ATOM 3721 C C . THR A 1 468 ? -12.898 -24.109 16.897 1.00 33.80 ? 495 THR A C 1 ATOM 3722 O O . THR A 1 468 ? -13.204 -23.211 16.115 1.00 32.19 ? 495 THR A O 1 ATOM 3723 C CB . THR A 1 468 ? -11.386 -25.807 15.782 1.00 37.49 ? 495 THR A CB 1 ATOM 3724 O OG1 . THR A 1 468 ? -12.336 -26.848 16.038 1.00 32.85 ? 495 THR A OG1 1 ATOM 3725 C CG2 . THR A 1 468 ? -9.988 -26.400 15.745 1.00 33.22 ? 495 THR A CG2 1 ATOM 3726 N N . MET A 1 469 ? -13.748 -24.600 17.794 1.00 30.62 ? 496 MET A N 1 ATOM 3727 C CA . MET A 1 469 ? -15.098 -24.073 17.944 1.00 26.49 ? 496 MET A CA 1 ATOM 3728 C C . MET A 1 469 ? -15.148 -23.121 19.129 1.00 34.73 ? 496 MET A C 1 ATOM 3729 O O . MET A 1 469 ? -15.442 -23.524 20.256 1.00 34.18 ? 496 MET A O 1 ATOM 3730 C CB . MET A 1 469 ? -16.095 -25.210 18.151 1.00 24.04 ? 496 MET A CB 1 ATOM 3731 C CG . MET A 1 469 ? -16.109 -26.229 17.032 1.00 27.18 ? 496 MET A CG 1 ATOM 3732 S SD . MET A 1 469 ? -17.053 -27.707 17.447 1.00 20.86 ? 496 MET A SD 1 ATOM 3733 C CE . MET A 1 469 ? -16.811 -28.678 15.970 1.00 18.14 ? 496 MET A CE 1 ATOM 3734 N N . LEU A 1 470 ? -14.856 -21.853 18.872 1.00 37.39 ? 497 LEU A N 1 ATOM 3735 C CA . LEU A 1 470 ? -14.773 -20.866 19.939 1.00 37.35 ? 497 LEU A CA 1 ATOM 3736 C C . LEU A 1 470 ? -16.137 -20.249 20.223 1.00 38.88 ? 497 LEU A C 1 ATOM 3737 O O . LEU A 1 470 ? -16.370 -19.691 21.297 1.00 39.71 ? 497 LEU A O 1 ATOM 3738 C CB . LEU A 1 470 ? -13.758 -19.778 19.580 1.00 36.28 ? 497 LEU A CB 1 ATOM 3739 C CG . LEU A 1 470 ? -12.306 -20.222 19.365 1.00 36.49 ? 497 LEU A CG 1 ATOM 3740 C CD1 . LEU A 1 470 ? -12.066 -20.691 17.932 1.00 31.93 ? 497 LEU A CD1 1 ATOM 3741 C CD2 . LEU A 1 470 ? -11.340 -19.107 19.739 1.00 38.48 ? 497 LEU A CD2 1 ATOM 3742 N N . GLN A 1 471 ? -17.038 -20.360 19.254 1.00 38.21 ? 498 GLN A N 1 ATOM 3743 C CA . GLN A 1 471 ? -18.359 -19.759 19.368 1.00 37.90 ? 498 GLN A CA 1 ATOM 3744 C C . GLN A 1 471 ? -19.349 -20.675 20.080 1.00 34.66 ? 498 GLN A C 1 ATOM 3745 O O . GLN A 1 471 ? -20.433 -20.243 20.469 1.00 35.21 ? 498 GLN A O 1 ATOM 3746 C CB . GLN A 1 471 ? -18.886 -19.393 17.981 1.00 43.11 ? 498 GLN A CB 1 ATOM 3747 C CG . GLN A 1 471 ? -18.101 -18.293 17.276 1.00 49.39 ? 498 GLN A CG 1 ATOM 3748 C CD . GLN A 1 471 ? -18.482 -16.896 17.744 1.00 52.00 ? 498 GLN A CD 1 ATOM 3749 O OE1 . GLN A 1 471 ? -18.601 -16.635 18.946 1.00 44.58 ? 498 GLN A OE1 1 ATOM 3750 N NE2 . GLN A 1 471 ? -18.680 -15.988 16.789 1.00 43.81 ? 498 GLN A NE2 1 ATOM 3751 N N . LEU A 1 472 ? -18.957 -21.934 20.250 1.00 33.83 ? 499 LEU A N 1 ATOM 3752 C CA . LEU A 1 472 ? -19.808 -22.971 20.836 1.00 30.29 ? 499 LEU A CA 1 ATOM 3753 C C . LEU A 1 472 ? -20.506 -22.559 22.128 1.00 31.25 ? 499 LEU A C 1 ATOM 3754 O O . LEU A 1 472 ? -19.867 -22.182 23.111 1.00 33.90 ? 499 LEU A O 1 ATOM 3755 C CB . LEU A 1 472 ? -18.992 -24.238 21.081 1.00 29.74 ? 499 LEU A CB 1 ATOM 3756 C CG . LEU A 1 472 ? -19.604 -25.529 20.549 1.00 24.66 ? 499 LEU A CG 1 ATOM 3757 C CD1 . LEU A 1 472 ? -18.588 -26.644 20.616 1.00 23.75 ? 499 LEU A CD1 1 ATOM 3758 C CD2 . LEU A 1 472 ? -20.833 -25.881 21.347 1.00 26.43 ? 499 LEU A CD2 1 ATOM 3759 N N . ARG A 1 473 ? -21.829 -22.649 22.113 1.00 34.10 ? 500 ARG A N 1 ATOM 3760 C CA . ARG A 1 473 ? -22.643 -22.240 23.245 1.00 36.11 ? 500 ARG A CA 1 ATOM 3761 C C . ARG A 1 473 ? -23.279 -23.452 23.894 1.00 32.43 ? 500 ARG A C 1 ATOM 3762 O O . ARG A 1 473 ? -23.485 -23.494 25.108 1.00 31.00 ? 500 ARG A O 1 ATOM 3763 C CB . ARG A 1 473 ? -23.736 -21.286 22.775 1.00 35.75 ? 500 ARG A CB 1 ATOM 3764 C CG . ARG A 1 473 ? -24.639 -20.781 23.878 1.00 40.21 ? 500 ARG A CG 1 ATOM 3765 C CD . ARG A 1 473 ? -24.769 -19.281 23.774 1.00 52.77 ? 500 ARG A CD 1 ATOM 3766 N NE . ARG A 1 473 ? -24.946 -18.869 22.385 1.00 64.61 ? 500 ARG A NE 1 ATOM 3767 C CZ . ARG A 1 473 ? -24.766 -17.628 21.944 1.00 71.56 ? 500 ARG A CZ 1 ATOM 3768 N NH1 . ARG A 1 473 ? -24.398 -16.669 22.785 1.00 74.09 1 500 ARG A NH1 1 ATOM 3769 N NH2 . ARG A 1 473 ? -24.950 -17.345 20.661 1.00 66.55 ? 500 ARG A NH2 1 ATOM 3770 N N . GLU A 1 474 ? -23.586 -24.445 23.071 1.00 29.18 ? 501 GLU A N 1 ATOM 3771 C CA . GLU A 1 474 ? -24.332 -25.599 23.534 1.00 29.04 ? 501 GLU A CA 1 ATOM 3772 C C . GLU A 1 474 ? -23.657 -26.897 23.133 1.00 24.08 ? 501 GLU A C 1 ATOM 3773 O O . GLU A 1 474 ? -23.579 -27.225 21.951 1.00 20.90 ? 501 GLU A O 1 ATOM 3774 C CB . GLU A 1 474 ? -25.752 -25.555 22.971 1.00 34.36 ? 501 GLU A CB 1 ATOM 3775 C CG . GLU A 1 474 ? -26.624 -26.714 23.408 1.00 34.64 ? 501 GLU A CG 1 ATOM 3776 C CD . GLU A 1 474 ? -26.779 -26.781 24.910 1.00 37.67 ? 501 GLU A CD 1 ATOM 3777 O OE1 . GLU A 1 474 ? -26.775 -25.712 25.559 1.00 38.20 ? 501 GLU A OE1 1 ATOM 3778 O OE2 . GLU A 1 474 ? -26.898 -27.905 25.442 1.00 44.29 1 501 GLU A OE2 1 ATOM 3779 N N . LEU A 1 475 ? -23.175 -27.638 24.126 1.00 26.52 ? 502 LEU A N 1 ATOM 3780 C CA . LEU A 1 475 ? -22.534 -28.923 23.867 1.00 25.97 ? 502 LEU A CA 1 ATOM 3781 C C . LEU A 1 475 ? -23.139 -30.025 24.724 1.00 18.16 ? 502 LEU A C 1 ATOM 3782 O O . LEU A 1 475 ? -23.157 -29.938 25.950 1.00 15.18 ? 502 LEU A O 1 ATOM 3783 C CB . LEU A 1 475 ? -21.026 -28.832 24.088 1.00 22.35 ? 502 LEU A CB 1 ATOM 3784 C CG . LEU A 1 475 ? -20.195 -29.896 23.379 1.00 17.67 ? 502 LEU A CG 1 ATOM 3785 C CD1 . LEU A 1 475 ? -18.826 -29.341 23.085 1.00 30.25 ? 502 LEU A CD1 1 ATOM 3786 C CD2 . LEU A 1 475 ? -20.076 -31.128 24.236 1.00 18.72 ? 502 LEU A CD2 1 ATOM 3787 N N . ASP A 1 476 ? -23.629 -31.065 24.062 1.00 16.12 ? 503 ASP A N 1 ATOM 3788 C CA . ASP A 1 476 ? -24.354 -32.118 24.746 1.00 18.54 ? 503 ASP A CA 1 ATOM 3789 C C . ASP A 1 476 ? -23.707 -33.468 24.510 1.00 19.83 ? 503 ASP A C 1 ATOM 3790 O O . ASP A 1 476 ? -23.933 -34.100 23.479 1.00 18.80 ? 503 ASP A O 1 ATOM 3791 C CB . ASP A 1 476 ? -25.806 -32.153 24.280 1.00 17.45 ? 503 ASP A CB 1 ATOM 3792 C CG . ASP A 1 476 ? -26.701 -32.919 25.229 1.00 19.35 ? 503 ASP A CG 1 ATOM 3793 O OD1 . ASP A 1 476 ? -26.189 -33.778 25.981 1.00 18.71 ? 503 ASP A OD1 1 ATOM 3794 O OD2 . ASP A 1 476 ? -27.921 -32.660 25.224 1.00 20.60 1 503 ASP A OD2 1 ATOM 3795 N N . LEU A 1 477 ? -22.911 -33.906 25.481 1.00 20.45 ? 504 LEU A N 1 ATOM 3796 C CA . LEU A 1 477 ? -22.244 -35.195 25.406 1.00 15.83 ? 504 LEU A CA 1 ATOM 3797 C C . LEU A 1 477 ? -22.802 -36.148 26.439 1.00 16.43 ? 504 LEU A C 1 ATOM 3798 O O . LEU A 1 477 ? -22.187 -37.166 26.745 1.00 19.01 ? 504 LEU A O 1 ATOM 3799 C CB . LEU A 1 477 ? -20.741 -35.036 25.607 1.00 13.07 ? 504 LEU A CB 1 ATOM 3800 C CG . LEU A 1 477 ? -19.992 -34.680 24.328 1.00 13.54 ? 504 LEU A CG 1 ATOM 3801 C CD1 . LEU A 1 477 ? -18.510 -34.468 24.604 1.00 10.57 ? 504 LEU A CD1 1 ATOM 3802 C CD2 . LEU A 1 477 ? -20.220 -35.760 23.280 1.00 13.31 ? 504 LEU A CD2 1 ATOM 3803 N N . SER A 1 478 ? -23.970 -35.818 26.975 1.00 14.40 ? 505 SER A N 1 ATOM 3804 C CA . SER A 1 478 ? -24.615 -36.684 27.948 1.00 19.41 ? 505 SER A CA 1 ATOM 3805 C C . SER A 1 478 ? -24.944 -38.035 27.326 1.00 24.04 ? 505 SER A C 1 ATOM 3806 O O . SER A 1 478 ? -25.196 -38.121 26.123 1.00 25.92 ? 505 SER A O 1 ATOM 3807 C CB . SER A 1 478 ? -25.896 -36.039 28.447 1.00 19.01 ? 505 SER A CB 1 ATOM 3808 O OG . SER A 1 478 ? -26.785 -35.854 27.368 1.00 18.83 ? 505 SER A OG 1 ATOM 3809 N N . TYR A 1 479 ? -24.932 -39.080 28.150 1.00 24.39 ? 506 TYR A N 1 ATOM 3810 C CA . TYR A 1 479 ? -25.324 -40.426 27.731 1.00 26.36 ? 506 TYR A CA 1 ATOM 3811 C C . TYR A 1 479 ? -24.399 -41.003 26.667 1.00 24.11 ? 506 TYR A C 1 ATOM 3812 O O . TYR A 1 479 ? -24.833 -41.733 25.774 1.00 26.17 ? 506 TYR A O 1 ATOM 3813 C CB . TYR A 1 479 ? -26.777 -40.461 27.240 1.00 23.08 ? 506 TYR A CB 1 ATOM 3814 C CG . TYR A 1 479 ? -27.812 -40.427 28.335 1.00 21.20 ? 506 TYR A CG 1 ATOM 3815 C CD1 . TYR A 1 479 ? -28.168 -41.582 29.012 1.00 24.99 ? 506 TYR A CD1 1 ATOM 3816 C CD2 . TYR A 1 479 ? -28.449 -39.243 28.680 1.00 20.89 ? 506 TYR A CD2 1 ATOM 3817 C CE1 . TYR A 1 479 ? -29.127 -41.559 30.010 1.00 26.26 ? 506 TYR A CE1 1 ATOM 3818 C CE2 . TYR A 1 479 ? -29.409 -39.213 29.674 1.00 21.34 ? 506 TYR A CE2 1 ATOM 3819 C CZ . TYR A 1 479 ? -29.742 -40.374 30.335 1.00 20.41 ? 506 TYR A CZ 1 ATOM 3820 O OH . TYR A 1 479 ? -30.690 -40.358 31.328 1.00 17.79 ? 506 TYR A OH 1 ATOM 3821 N N . ASN A 1 480 ? -23.121 -40.677 26.761 1.00 18.43 ? 507 ASN A N 1 ATOM 3822 C CA . ASN A 1 480 ? -22.152 -41.342 25.919 1.00 25.22 ? 507 ASN A CA 1 ATOM 3823 C C . ASN A 1 480 ? -21.345 -42.395 26.671 1.00 29.70 ? 507 ASN A C 1 ATOM 3824 O O . ASN A 1 480 ? -21.842 -43.047 27.592 1.00 27.56 ? 507 ASN A O 1 ATOM 3825 C CB . ASN A 1 480 ? -21.240 -40.324 25.232 1.00 26.77 ? 507 ASN A CB 1 ATOM 3826 C CG . ASN A 1 480 ? -21.919 -39.632 24.064 1.00 23.71 ? 507 ASN A CG 1 ATOM 3827 O OD1 . ASN A 1 480 ? -21.819 -40.076 22.920 1.00 18.00 ? 507 ASN A OD1 1 ATOM 3828 N ND2 . ASN A 1 480 ? -22.611 -38.534 24.348 1.00 23.30 ? 507 ASN A ND2 1 ATOM 3829 N N . ASN A 1 481 ? -20.095 -42.557 26.261 1.00 26.88 ? 508 ASN A N 1 ATOM 3830 C CA . ASN A 1 481 ? -19.227 -43.579 26.825 1.00 26.40 ? 508 ASN A CA 1 ATOM 3831 C C . ASN A 1 481 ? -17.815 -43.053 27.058 1.00 30.84 ? 508 ASN A C 1 ATOM 3832 O O . ASN A 1 481 ? -16.829 -43.639 26.609 1.00 28.62 ? 508 ASN A O 1 ATOM 3833 C CB . ASN A 1 481 ? -19.210 -44.816 25.926 1.00 29.28 ? 508 ASN A CB 1 ATOM 3834 C CG . ASN A 1 481 ? -18.722 -46.052 26.651 1.00 45.02 ? 508 ASN A CG 1 ATOM 3835 O OD1 . ASN A 1 481 ? -18.041 -45.940 27.668 1.00 45.46 ? 508 ASN A OD1 1 ATOM 3836 N ND2 . ASN A 1 481 ? -19.053 -47.242 26.128 1.00 52.36 ? 508 ASN A ND2 1 ATOM 3837 N N . ILE A 1 482 ? -17.749 -41.923 27.753 1.00 32.89 ? 509 ILE A N 1 ATOM 3838 C CA . ILE A 1 482 ? -16.503 -41.343 28.209 1.00 25.91 ? 509 ILE A CA 1 ATOM 3839 C C . ILE A 1 482 ? -16.262 -41.901 29.600 1.00 31.98 ? 509 ILE A C 1 ATOM 3840 O O . ILE A 1 482 ? -17.120 -41.803 30.478 1.00 27.16 ? 509 ILE A O 1 ATOM 3841 C CB . ILE A 1 482 ? -16.595 -39.816 28.265 1.00 18.50 ? 509 ILE A CB 1 ATOM 3842 C CG1 . ILE A 1 482 ? -17.236 -39.287 26.982 1.00 16.57 ? 509 ILE A CG1 1 ATOM 3843 C CG2 . ILE A 1 482 ? -15.226 -39.212 28.490 1.00 26.69 ? 509 ILE A CG2 1 ATOM 3844 C CD1 . ILE A 1 482 ? -17.136 -37.796 26.805 1.00 11.70 ? 509 ILE A CD1 1 ATOM 3845 N N . SER A 1 483 ? -15.092 -42.501 29.785 1.00 33.78 ? 510 SER A N 1 ATOM 3846 C CA . SER A 1 483 ? -14.801 -43.262 30.991 1.00 28.65 ? 510 SER A CA 1 ATOM 3847 C C . SER A 1 483 ? -13.950 -42.501 32.002 1.00 31.91 ? 510 SER A C 1 ATOM 3848 O O . SER A 1 483 ? -13.981 -42.805 33.195 1.00 33.81 ? 510 SER A O 1 ATOM 3849 C CB . SER A 1 483 ? -14.100 -44.564 30.618 1.00 29.16 ? 510 SER A CB 1 ATOM 3850 O OG . SER A 1 483 ? -13.014 -44.302 29.744 1.00 31.22 ? 510 SER A OG 1 ATOM 3851 N N . SER A 1 484 ? -13.188 -41.521 31.525 1.00 31.73 ? 511 SER A N 1 ATOM 3852 C CA . SER A 1 484 ? -12.265 -40.787 32.382 1.00 28.34 ? 511 SER A CA 1 ATOM 3853 C C . SER A 1 484 ? -12.005 -39.387 31.851 1.00 32.99 ? 511 SER A C 1 ATOM 3854 O O . SER A 1 484 ? -11.908 -39.177 30.638 1.00 35.05 ? 511 SER A O 1 ATOM 3855 C CB . SER A 1 484 ? -10.937 -41.533 32.487 1.00 28.74 ? 511 SER A CB 1 ATOM 3856 O OG . SER A 1 484 ? -10.255 -41.524 31.243 1.00 22.41 ? 511 SER A OG 1 ATOM 3857 N N . LEU A 1 485 ? -11.882 -38.433 32.769 1.00 32.48 ? 512 LEU A N 1 ATOM 3858 C CA . LEU A 1 485 ? -11.546 -37.062 32.408 1.00 33.52 ? 512 LEU A CA 1 ATOM 3859 C C . LEU A 1 485 ? -10.141 -36.713 32.866 1.00 35.73 ? 512 LEU A C 1 ATOM 3860 O O . LEU A 1 485 ? -9.619 -37.319 33.799 1.00 33.76 ? 512 LEU A O 1 ATOM 3861 C CB . LEU A 1 485 ? -12.529 -36.081 33.041 1.00 28.73 ? 512 LEU A CB 1 ATOM 3862 C CG . LEU A 1 485 ? -14.000 -36.231 32.669 1.00 35.59 ? 512 LEU A CG 1 ATOM 3863 C CD1 . LEU A 1 485 ? -14.834 -35.149 33.339 1.00 31.86 ? 512 LEU A CD1 1 ATOM 3864 C CD2 . LEU A 1 485 ? -14.172 -36.189 31.157 1.00 48.28 ? 512 LEU A CD2 1 ATOM 3865 N N . GLY A 1 486 ? -9.539 -35.739 32.189 1.00 42.27 ? 513 GLY A N 1 ATOM 3866 C CA . GLY A 1 486 ? -8.303 -35.112 32.630 1.00 38.91 ? 513 GLY A CA 1 ATOM 3867 C C . GLY A 1 486 ? -8.533 -33.613 32.594 1.00 41.27 ? 513 GLY A C 1 ATOM 3868 O O . GLY A 1 486 ? -9.499 -33.160 31.983 1.00 45.93 ? 513 GLY A O 1 ATOM 3869 N N . TYR A 1 487 ? -7.663 -32.832 33.229 1.00 42.12 ? 514 TYR A N 1 ATOM 3870 C CA . TYR A 1 487 ? -7.858 -31.379 33.276 1.00 47.54 ? 514 TYR A CA 1 ATOM 3871 C C . TYR A 1 487 ? -7.819 -30.732 31.886 1.00 44.16 ? 514 TYR A C 1 ATOM 3872 O O . TYR A 1 487 ? -8.144 -29.557 31.734 1.00 43.18 ? 514 TYR A O 1 ATOM 3873 C CB . TYR A 1 487 ? -6.840 -30.707 34.211 1.00 54.81 ? 514 TYR A CB 1 ATOM 3874 C CG . TYR A 1 487 ? -5.437 -30.621 33.642 1.00 57.67 ? 514 TYR A CG 1 ATOM 3875 C CD1 . TYR A 1 487 ? -4.548 -31.681 33.770 1.00 57.38 ? 514 TYR A CD1 1 ATOM 3876 C CD2 . TYR A 1 487 ? -5.003 -29.481 32.977 1.00 55.90 ? 514 TYR A CD2 1 ATOM 3877 C CE1 . TYR A 1 487 ? -3.270 -31.610 33.248 1.00 53.11 ? 514 TYR A CE1 1 ATOM 3878 C CE2 . TYR A 1 487 ? -3.725 -29.404 32.452 1.00 55.05 ? 514 TYR A CE2 1 ATOM 3879 C CZ . TYR A 1 487 ? -2.864 -30.470 32.590 1.00 53.09 ? 514 TYR A CZ 1 ATOM 3880 O OH . TYR A 1 487 ? -1.591 -30.398 32.069 1.00 54.36 ? 514 TYR A OH 1 ATOM 3881 N N . GLU A 1 488 ? -7.411 -31.504 30.883 1.00 47.55 ? 515 GLU A N 1 ATOM 3882 C CA . GLU A 1 488 ? -7.368 -31.034 29.501 1.00 47.60 ? 515 GLU A CA 1 ATOM 3883 C C . GLU A 1 488 ? -8.706 -31.305 28.823 1.00 48.48 ? 515 GLU A C 1 ATOM 3884 O O . GLU A 1 488 ? -8.997 -30.769 27.750 1.00 49.06 ? 515 GLU A O 1 ATOM 3885 C CB . GLU A 1 488 ? -6.250 -31.734 28.724 1.00 49.49 ? 515 GLU A CB 1 ATOM 3886 C CG . GLU A 1 488 ? -4.912 -31.806 29.446 1.00 49.45 ? 515 GLU A CG 1 ATOM 3887 C CD . GLU A 1 488 ? -4.782 -33.030 30.339 1.00 47.94 ? 515 GLU A CD 1 ATOM 3888 O OE1 . GLU A 1 488 ? -5.816 -33.610 30.737 1.00 48.34 ? 515 GLU A OE1 1 ATOM 3889 O OE2 . GLU A 1 488 ? -3.636 -33.415 30.642 1.00 53.39 1 515 GLU A OE2 1 ATOM 3890 N N . ASP A 1 489 ? -9.513 -32.150 29.455 1.00 43.84 ? 516 ASP A N 1 ATOM 3891 C CA . ASP A 1 489 ? -10.856 -32.437 28.972 1.00 39.23 ? 516 ASP A CA 1 ATOM 3892 C C . ASP A 1 489 ? -11.845 -31.372 29.437 1.00 45.70 ? 516 ASP A C 1 ATOM 3893 O O . ASP A 1 489 ? -13.053 -31.497 29.224 1.00 41.46 ? 516 ASP A O 1 ATOM 3894 C CB . ASP A 1 489 ? -11.305 -33.812 29.451 1.00 32.45 ? 516 ASP A CB 1 ATOM 3895 C CG . ASP A 1 489 ? -10.461 -34.916 28.882 1.00 36.74 ? 516 ASP A CG 1 ATOM 3896 O OD1 . ASP A 1 489 ? -9.876 -34.707 27.797 1.00 37.99 ? 516 ASP A OD1 1 ATOM 3897 O OD2 . ASP A 1 489 ? -10.384 -35.989 29.516 1.00 43.44 1 516 ASP A OD2 1 ATOM 3898 N N . LEU A 1 490 ? -11.323 -30.329 30.076 1.00 42.16 ? 517 LEU A N 1 ATOM 3899 C CA . LEU A 1 490 ? -12.144 -29.225 30.552 1.00 35.26 ? 517 LEU A CA 1 ATOM 3900 C C . LEU A 1 490 ? -11.579 -27.883 30.092 1.00 41.80 ? 517 LEU A C 1 ATOM 3901 O O . LEU A 1 490 ? -11.795 -26.857 30.734 1.00 48.05 ? 517 LEU A O 1 ATOM 3902 C CB . LEU A 1 490 ? -12.252 -29.271 32.075 1.00 28.31 ? 517 LEU A CB 1 ATOM 3903 C CG . LEU A 1 490 ? -12.970 -30.505 32.619 1.00 28.46 ? 517 LEU A CG 1 ATOM 3904 C CD1 . LEU A 1 490 ? -12.844 -30.591 34.122 1.00 38.67 ? 517 LEU A CD1 1 ATOM 3905 C CD2 . LEU A 1 490 ? -14.425 -30.471 32.226 1.00 29.71 ? 517 LEU A CD2 1 ATOM 3906 N N . ALA A 1 491 ? -10.868 -27.899 28.967 1.00 44.18 ? 518 ALA A N 1 ATOM 3907 C CA . ALA A 1 491 ? -10.191 -26.709 28.457 1.00 41.84 ? 518 ALA A CA 1 ATOM 3908 C C . ALA A 1 491 ? -10.882 -26.128 27.231 1.00 43.97 ? 518 ALA A C 1 ATOM 3909 O O . ALA A 1 491 ? -10.333 -26.177 26.133 1.00 53.23 ? 518 ALA A O 1 ATOM 3910 C CB . ALA A 1 491 ? -8.744 -27.033 28.122 1.00 32.50 ? 518 ALA A CB 1 ATOM 3911 N N . PHE A 1 492 ? -12.070 -25.564 27.411 1.00 34.74 ? 519 PHE A N 1 ATOM 3912 C CA . PHE A 1 492 ? -12.816 -25.045 26.271 1.00 40.16 ? 519 PHE A CA 1 ATOM 3913 C C . PHE A 1 492 ? -12.588 -23.555 26.004 1.00 41.28 ? 519 PHE A C 1 ATOM 3914 O O . PHE A 1 492 ? -12.962 -22.696 26.806 1.00 40.74 ? 519 PHE A O 1 ATOM 3915 C CB . PHE A 1 492 ? -14.307 -25.345 26.423 1.00 47.09 ? 519 PHE A CB 1 ATOM 3916 C CG . PHE A 1 492 ? -14.637 -26.812 26.397 1.00 41.72 ? 519 PHE A CG 1 ATOM 3917 C CD1 . PHE A 1 492 ? -14.814 -27.476 25.194 1.00 36.76 ? 519 PHE A CD1 1 ATOM 3918 C CD2 . PHE A 1 492 ? -14.778 -27.525 27.576 1.00 38.56 ? 519 PHE A CD2 1 ATOM 3919 C CE1 . PHE A 1 492 ? -15.123 -28.823 25.169 1.00 31.53 ? 519 PHE A CE1 1 ATOM 3920 C CE2 . PHE A 1 492 ? -15.088 -28.873 27.555 1.00 33.14 ? 519 PHE A CE2 1 ATOM 3921 C CZ . PHE A 1 492 ? -15.259 -29.522 26.350 1.00 30.72 ? 519 PHE A CZ 1 ATOM 3922 N N . LEU A 1 493 ? -11.985 -23.266 24.855 1.00 41.47 ? 520 LEU A N 1 ATOM 3923 C CA . LEU A 1 493 ? -11.699 -21.897 24.434 1.00 47.43 ? 520 LEU A CA 1 ATOM 3924 C C . LEU A 1 493 ? -12.924 -21.203 23.848 1.00 40.85 ? 520 LEU A C 1 ATOM 3925 O O . LEU A 1 493 ? -12.892 -20.741 22.706 1.00 34.14 ? 520 LEU A O 1 ATOM 3926 C CB . LEU A 1 493 ? -10.590 -21.890 23.379 1.00 47.21 ? 520 LEU A CB 1 ATOM 3927 C CG . LEU A 1 493 ? -9.124 -21.852 23.806 1.00 42.85 ? 520 LEU A CG 1 ATOM 3928 C CD1 . LEU A 1 493 ? -8.804 -22.945 24.809 1.00 45.22 ? 520 LEU A CD1 1 ATOM 3929 C CD2 . LEU A 1 493 ? -8.246 -21.980 22.572 1.00 44.64 ? 520 LEU A CD2 1 ATOM 3930 N N . SER A 1 494 ? -13.999 -21.126 24.623 1.00 41.10 ? 521 SER A N 1 ATOM 3931 C CA . SER A 1 494 ? -15.213 -20.474 24.147 1.00 49.62 ? 521 SER A CA 1 ATOM 3932 C C . SER A 1 494 ? -15.595 -19.294 25.026 1.00 53.15 ? 521 SER A C 1 ATOM 3933 O O . SER A 1 494 ? -15.979 -19.464 26.184 1.00 54.04 ? 521 SER A O 1 ATOM 3934 C CB . SER A 1 494 ? -16.377 -21.467 24.040 1.00 43.69 ? 521 SER A CB 1 ATOM 3935 O OG . SER A 1 494 ? -16.242 -22.292 22.892 1.00 34.71 ? 521 SER A OG 1 ATOM 3936 N N . GLN A 1 495 ? -15.484 -18.095 24.461 1.00 54.36 ? 522 GLN A N 1 ATOM 3937 C CA . GLN A 1 495 ? -15.876 -16.873 25.156 1.00 63.44 ? 522 GLN A CA 1 ATOM 3938 C C . GLN A 1 495 ? -17.369 -16.610 24.981 1.00 57.33 ? 522 GLN A C 1 ATOM 3939 O O . GLN A 1 495 ? -17.807 -15.461 24.910 1.00 53.52 ? 522 GLN A O 1 ATOM 3940 C CB . GLN A 1 495 ? -15.062 -15.680 24.642 1.00 63.27 ? 522 GLN A CB 1 ATOM 3941 C CG . GLN A 1 495 ? -13.672 -15.550 25.254 1.00 56.64 ? 522 GLN A CG 1 ATOM 3942 C CD . GLN A 1 495 ? -13.704 -15.038 26.688 1.00 57.54 ? 522 GLN A CD 1 ATOM 3943 O OE1 . GLN A 1 495 ? -14.239 -15.691 27.589 1.00 47.93 ? 522 GLN A OE1 1 ATOM 3944 N NE2 . GLN A 1 495 ? -13.132 -13.860 26.902 1.00 55.75 ? 522 GLN A NE2 1 ATOM 3945 N N . ASN A 1 496 ? -18.146 -17.685 24.928 1.00 56.85 ? 523 ASN A N 1 ATOM 3946 C CA . ASN A 1 496 ? -19.553 -17.592 24.575 1.00 54.62 ? 523 ASN A CA 1 ATOM 3947 C C . ASN A 1 496 ? -20.420 -18.554 25.379 1.00 47.20 ? 523 ASN A C 1 ATOM 3948 O O . ASN A 1 496 ? -20.868 -19.570 24.851 1.00 46.58 ? 523 ASN A O 1 ATOM 3949 C CB . ASN A 1 496 ? -19.719 -17.858 23.076 1.00 55.01 ? 523 ASN A CB 1 ATOM 3950 C CG . ASN A 1 496 ? -21.114 -17.556 22.580 1.00 48.16 ? 523 ASN A CG 1 ATOM 3951 O OD1 . ASN A 1 496 ? -21.877 -16.844 23.233 1.00 48.46 ? 523 ASN A OD1 1 ATOM 3952 N ND2 . ASN A 1 496 ? -21.455 -18.097 21.416 1.00 42.73 ? 523 ASN A ND2 1 ATOM 3953 N N . ARG A 1 497 ? -20.635 -18.215 26.652 1.00 48.93 ? 524 ARG A N 1 ATOM 3954 C CA . ARG A 1 497 ? -21.497 -18.958 27.584 1.00 49.02 ? 524 ARG A CA 1 ATOM 3955 C C . ARG A 1 497 ? -21.718 -20.428 27.253 1.00 43.83 ? 524 ARG A C 1 ATOM 3956 O O . ARG A 1 497 ? -22.858 -20.874 27.111 1.00 43.13 ? 524 ARG A O 1 ATOM 3957 C CB . ARG A 1 497 ? -22.854 -18.267 27.731 1.00 51.78 ? 524 ARG A CB 1 ATOM 3958 C CG . ARG A 1 497 ? -22.834 -17.009 28.588 1.00 57.31 ? 524 ARG A CG 1 ATOM 3959 C CD . ARG A 1 497 ? -24.193 -16.319 28.596 1.00 60.99 ? 524 ARG A CD 1 ATOM 3960 N NE . ARG A 1 497 ? -24.530 -15.740 27.296 1.00 68.96 ? 524 ARG A NE 1 ATOM 3961 C CZ . ARG A 1 497 ? -25.287 -16.336 26.377 1.00 70.42 ? 524 ARG A CZ 1 ATOM 3962 N NH1 . ARG A 1 497 ? -25.534 -15.725 25.226 1.00 72.58 1 524 ARG A NH1 1 ATOM 3963 N NH2 . ARG A 1 497 ? -25.798 -17.539 26.605 1.00 65.80 ? 524 ARG A NH2 1 ATOM 3964 N N . LEU A 1 498 ? -20.624 -21.170 27.118 1.00 41.49 ? 525 LEU A N 1 ATOM 3965 C CA . LEU A 1 498 ? -20.703 -22.586 26.789 1.00 38.40 ? 525 LEU A CA 1 ATOM 3966 C C . LEU A 1 498 ? -21.201 -23.419 27.972 1.00 37.18 ? 525 LEU A C 1 ATOM 3967 O O . LEU A 1 498 ? -20.702 -23.289 29.093 1.00 37.66 ? 525 LEU A O 1 ATOM 3968 C CB . LEU A 1 498 ? -19.344 -23.093 26.306 1.00 34.86 ? 525 LEU A CB 1 ATOM 3969 C CG . LEU A 1 498 ? -19.217 -24.598 26.072 1.00 31.89 ? 525 LEU A CG 1 ATOM 3970 C CD1 . LEU A 1 498 ? -20.286 -25.089 25.115 1.00 31.72 ? 525 LEU A CD1 1 ATOM 3971 C CD2 . LEU A 1 498 ? -17.835 -24.924 25.537 1.00 35.88 ? 525 LEU A CD2 1 ATOM 3972 N N . HIS A 1 499 ? -22.197 -24.263 27.714 1.00 32.87 ? 526 HIS A N 1 ATOM 3973 C CA . HIS A 1 499 ? -22.707 -25.193 28.716 1.00 31.41 ? 526 HIS A CA 1 ATOM 3974 C C . HIS A 1 499 ? -22.620 -26.635 28.227 1.00 28.95 ? 526 HIS A C 1 ATOM 3975 O O . HIS A 1 499 ? -23.483 -27.111 27.486 1.00 29.46 ? 526 HIS A O 1 ATOM 3976 C CB . HIS A 1 499 ? -24.152 -24.870 29.081 1.00 32.71 ? 526 HIS A CB 1 ATOM 3977 C CG . HIS A 1 499 ? -24.295 -23.765 30.079 1.00 31.59 ? 526 HIS A CG 1 ATOM 3978 N ND1 . HIS A 1 499 ? -23.824 -22.490 29.852 1.00 35.41 ? 526 HIS A ND1 1 ATOM 3979 C CD2 . HIS A 1 499 ? -24.875 -23.741 31.302 1.00 32.52 ? 526 HIS A CD2 1 ATOM 3980 C CE1 . HIS A 1 499 ? -24.103 -21.729 30.896 1.00 38.91 ? 526 HIS A CE1 1 ATOM 3981 N NE2 . HIS A 1 499 ? -24.741 -22.463 31.789 1.00 37.72 ? 526 HIS A NE2 1 ATOM 3982 N N . VAL A 1 500 ? -21.574 -27.325 28.659 1.00 23.33 ? 527 VAL A N 1 ATOM 3983 C CA . VAL A 1 500 ? -21.346 -28.708 28.285 1.00 19.76 ? 527 VAL A CA 1 ATOM 3984 C C . VAL A 1 500 ? -22.073 -29.669 29.218 1.00 22.83 ? 527 VAL A C 1 ATOM 3985 O O . VAL A 1 500 ? -22.004 -29.533 30.437 1.00 28.71 ? 527 VAL A O 1 ATOM 3986 C CB . VAL A 1 500 ? -19.849 -29.016 28.308 1.00 22.22 ? 527 VAL A CB 1 ATOM 3987 C CG1 . VAL A 1 500 ? -19.599 -30.518 28.283 1.00 22.98 ? 527 VAL A CG1 1 ATOM 3988 C CG2 . VAL A 1 500 ? -19.162 -28.316 27.146 1.00 29.08 ? 527 VAL A CG2 1 ATOM 3989 N N . ASN A 1 501 ? -22.775 -30.639 28.640 1.00 20.29 ? 528 ASN A N 1 ATOM 3990 C CA . ASN A 1 501 ? -23.480 -31.640 29.429 1.00 19.15 ? 528 ASN A CA 1 ATOM 3991 C C . ASN A 1 501 ? -22.778 -32.983 29.329 1.00 21.70 ? 528 ASN A C 1 ATOM 3992 O O . ASN A 1 501 ? -22.679 -33.553 28.242 1.00 22.21 ? 528 ASN A O 1 ATOM 3993 C CB . ASN A 1 501 ? -24.925 -31.770 28.950 1.00 21.39 ? 528 ASN A CB 1 ATOM 3994 C CG . ASN A 1 501 ? -25.876 -32.178 30.060 1.00 24.96 ? 528 ASN A CG 1 ATOM 3995 O OD1 . ASN A 1 501 ? -25.557 -33.043 30.877 1.00 22.52 ? 528 ASN A OD1 1 ATOM 3996 N ND2 . ASN A 1 501 ? -27.056 -31.544 30.095 1.00 28.63 ? 528 ASN A ND2 1 ATOM 3997 N N . MET A 1 502 ? -22.284 -33.482 30.461 1.00 24.72 ? 529 MET A N 1 ATOM 3998 C CA . MET A 1 502 ? -21.600 -34.773 30.504 1.00 19.24 ? 529 MET A CA 1 ATOM 3999 C C . MET A 1 502 ? -22.272 -35.735 31.473 1.00 19.24 ? 529 MET A C 1 ATOM 4000 O O . MET A 1 502 ? -21.611 -36.585 32.065 1.00 22.03 ? 529 MET A O 1 ATOM 4001 C CB . MET A 1 502 ? -20.134 -34.605 30.901 1.00 16.87 ? 529 MET A CB 1 ATOM 4002 C CG . MET A 1 502 ? -19.297 -33.778 29.936 1.00 22.65 ? 529 MET A CG 1 ATOM 4003 S SD . MET A 1 502 ? -17.545 -33.797 30.391 1.00 38.17 ? 529 MET A SD 1 ATOM 4004 C CE . MET A 1 502 ? -16.833 -32.687 29.177 1.00 29.98 ? 529 MET A CE 1 ATOM 4005 N N . THR A 1 503 ? -23.585 -35.598 31.627 1.00 18.51 ? 530 THR A N 1 ATOM 4006 C CA . THR A 1 503 ? -24.358 -36.458 32.517 1.00 21.62 ? 530 THR A CA 1 ATOM 4007 C C . THR A 1 503 ? -24.499 -37.891 32.004 1.00 22.96 ? 530 THR A C 1 ATOM 4008 O O . THR A 1 503 ? -24.440 -38.141 30.802 1.00 21.44 ? 530 THR A O 1 ATOM 4009 C CB . THR A 1 503 ? -25.770 -35.895 32.742 1.00 26.50 ? 530 THR A CB 1 ATOM 4010 O OG1 . THR A 1 503 ? -26.111 -35.021 31.659 1.00 25.41 ? 530 THR A OG1 1 ATOM 4011 C CG2 . THR A 1 503 ? -25.839 -35.121 34.042 1.00 30.03 ? 530 THR A CG2 1 ATOM 4012 N N . HIS A 1 504 ? -24.689 -38.819 32.938 1.00 25.56 ? 531 HIS A N 1 ATOM 4013 C CA . HIS A 1 504 ? -24.960 -40.230 32.640 1.00 26.35 ? 531 HIS A CA 1 ATOM 4014 C C . HIS A 1 504 ? -23.985 -40.913 31.678 1.00 25.67 ? 531 HIS A C 1 ATOM 4015 O O . HIS A 1 504 ? -24.400 -41.639 30.775 1.00 30.29 ? 531 HIS A O 1 ATOM 4016 C CB . HIS A 1 504 ? -26.391 -40.413 32.136 1.00 21.39 ? 531 HIS A CB 1 ATOM 4017 C CG . HIS A 1 504 ? -27.435 -39.933 33.090 1.00 24.55 ? 531 HIS A CG 1 ATOM 4018 N ND1 . HIS A 1 504 ? -27.594 -38.602 33.413 1.00 29.74 ? 531 HIS A ND1 1 ATOM 4019 C CD2 . HIS A 1 504 ? -28.381 -40.604 33.788 1.00 31.82 ? 531 HIS A CD2 1 ATOM 4020 C CE1 . HIS A 1 504 ? -28.593 -38.474 34.266 1.00 34.61 ? 531 HIS A CE1 1 ATOM 4021 N NE2 . HIS A 1 504 ? -29.088 -39.675 34.512 1.00 37.73 ? 531 HIS A NE2 1 ATOM 4022 N N . ASN A 1 505 ? -22.693 -40.696 31.872 1.00 21.05 ? 532 ASN A N 1 ATOM 4023 C CA . ASN A 1 505 ? -21.714 -41.416 31.078 1.00 24.05 ? 532 ASN A CA 1 ATOM 4024 C C . ASN A 1 505 ? -21.124 -42.602 31.827 1.00 28.06 ? 532 ASN A C 1 ATOM 4025 O O . ASN A 1 505 ? -21.807 -43.278 32.599 1.00 23.08 ? 532 ASN A O 1 ATOM 4026 C CB . ASN A 1 505 ? -20.609 -40.480 30.598 1.00 23.18 ? 532 ASN A CB 1 ATOM 4027 C CG . ASN A 1 505 ? -21.057 -39.597 29.454 1.00 25.47 ? 532 ASN A CG 1 ATOM 4028 O OD1 . ASN A 1 505 ? -20.652 -39.789 28.307 1.00 24.29 ? 532 ASN A OD1 1 ATOM 4029 N ND2 . ASN A 1 505 ? -21.909 -38.627 29.758 1.00 25.93 ? 532 ASN A ND2 1 ATOM 4030 N N . LYS A 1 506 ? -19.846 -42.849 31.582 1.00 30.67 ? 533 LYS A N 1 ATOM 4031 C CA . LYS A 1 506 ? -19.147 -43.944 32.223 1.00 33.42 ? 533 LYS A CA 1 ATOM 4032 C C . LYS A 1 506 ? -17.916 -43.400 32.923 1.00 34.24 ? 533 LYS A C 1 ATOM 4033 O O . LYS A 1 506 ? -16.931 -44.112 33.086 1.00 36.27 ? 533 LYS A O 1 ATOM 4034 C CB . LYS A 1 506 ? -18.731 -44.980 31.180 1.00 37.18 ? 533 LYS A CB 1 ATOM 4035 C CG . LYS A 1 506 ? -19.875 -45.474 30.312 1.00 31.62 ? 533 LYS A CG 1 ATOM 4036 C CD . LYS A 1 506 ? -20.328 -46.859 30.724 1.00 24.01 ? 533 LYS A CD 1 ATOM 4037 C CE . LYS A 1 506 ? -21.816 -46.876 30.972 1.00 24.09 ? 533 LYS A CE 1 ATOM 4038 N NZ . LYS A 1 506 ? -22.534 -46.111 29.918 1.00 39.94 1 533 LYS A NZ 1 ATOM 4039 N N . ILE A 1 507 ? -17.969 -42.133 33.324 1.00 31.90 ? 534 ILE A N 1 ATOM 4040 C CA . ILE A 1 507 ? -16.836 -41.501 33.988 1.00 29.71 ? 534 ILE A CA 1 ATOM 4041 C C . ILE A 1 507 ? -16.636 -42.112 35.365 1.00 32.45 ? 534 ILE A C 1 ATOM 4042 O O . ILE A 1 507 ? -17.370 -41.800 36.303 1.00 34.70 ? 534 ILE A O 1 ATOM 4043 C CB . ILE A 1 507 ? -17.027 -39.984 34.113 1.00 26.17 ? 534 ILE A CB 1 ATOM 4044 C CG1 . ILE A 1 507 ? -17.184 -39.357 32.731 1.00 26.15 ? 534 ILE A CG1 1 ATOM 4045 C CG2 . ILE A 1 507 ? -15.851 -39.351 34.824 1.00 33.08 ? 534 ILE A CG2 1 ATOM 4046 C CD1 . ILE A 1 507 ? -17.220 -37.859 32.761 1.00 23.83 ? 534 ILE A CD1 1 ATOM 4047 N N . ARG A 1 508 ? -15.647 -42.993 35.477 1.00 31.77 ? 535 ARG A N 1 ATOM 4048 C CA . ARG A 1 508 ? -15.412 -43.715 36.722 1.00 38.99 ? 535 ARG A CA 1 ATOM 4049 C C . ARG A 1 508 ? -14.304 -43.073 37.540 1.00 41.82 ? 535 ARG A C 1 ATOM 4050 O O . ARG A 1 508 ? -14.098 -43.428 38.698 1.00 45.77 ? 535 ARG A O 1 ATOM 4051 C CB . ARG A 1 508 ? -15.087 -45.187 36.451 1.00 42.06 ? 535 ARG A CB 1 ATOM 4052 C CG . ARG A 1 508 ? -16.061 -45.855 35.493 1.00 48.75 ? 535 ARG A CG 1 ATOM 4053 C CD . ARG A 1 508 ? -16.323 -47.312 35.837 1.00 49.59 ? 535 ARG A CD 1 ATOM 4054 N NE . ARG A 1 508 ? -17.205 -47.450 36.992 1.00 55.89 ? 535 ARG A NE 1 ATOM 4055 C CZ . ARG A 1 508 ? -16.794 -47.795 38.208 1.00 66.75 ? 535 ARG A CZ 1 ATOM 4056 N NH1 . ARG A 1 508 ? -15.508 -48.045 38.420 1.00 64.34 1 535 ARG A NH1 1 ATOM 4057 N NH2 . ARG A 1 508 ? -17.665 -47.898 39.208 1.00 55.94 ? 535 ARG A NH2 1 ATOM 4058 N N . ARG A 1 509 ? -13.597 -42.126 36.932 1.00 41.36 ? 536 ARG A N 1 ATOM 4059 C CA . ARG A 1 509 ? -12.551 -41.386 37.628 1.00 41.22 ? 536 ARG A CA 1 ATOM 4060 C C . ARG A 1 509 ? -12.340 -40.011 37.009 1.00 36.20 ? 536 ARG A C 1 ATOM 4061 O O . ARG A 1 509 ? -12.607 -39.807 35.827 1.00 40.51 ? 536 ARG A O 1 ATOM 4062 C CB . ARG A 1 509 ? -11.237 -42.173 37.633 1.00 49.78 ? 536 ARG A CB 1 ATOM 4063 C CG . ARG A 1 509 ? -10.757 -42.617 36.256 1.00 54.73 ? 536 ARG A CG 1 ATOM 4064 C CD . ARG A 1 509 ? -9.344 -43.182 36.326 1.00 63.75 ? 536 ARG A CD 1 ATOM 4065 N NE . ARG A 1 509 ? -9.251 -44.301 37.259 1.00 69.47 ? 536 ARG A NE 1 ATOM 4066 C CZ . ARG A 1 509 ? -8.158 -44.613 37.950 1.00 65.64 ? 536 ARG A CZ 1 ATOM 4067 N NH1 . ARG A 1 509 ? -7.056 -43.886 37.818 1.00 59.33 1 536 ARG A NH1 1 ATOM 4068 N NH2 . ARG A 1 509 ? -8.170 -45.649 38.778 1.00 58.90 ? 536 ARG A NH2 1 ATOM 4069 N N . ILE A 1 510 ? -11.867 -39.068 37.818 1.00 38.37 ? 537 ILE A N 1 ATOM 4070 C CA . ILE A 1 510 ? -11.521 -37.730 37.339 1.00 37.18 ? 537 ILE A CA 1 ATOM 4071 C C . ILE A 1 510 ? -10.135 -37.309 37.834 1.00 43.36 ? 537 ILE A C 1 ATOM 4072 O O . ILE A 1 510 ? -9.986 -36.803 38.947 1.00 47.34 ? 537 ILE A O 1 ATOM 4073 C CB . ILE A 1 510 ? -12.557 -36.688 37.781 1.00 29.07 ? 537 ILE A CB 1 ATOM 4074 C CG1 . ILE A 1 510 ? -13.955 -37.103 37.318 1.00 31.12 ? 537 ILE A CG1 1 ATOM 4075 C CG2 . ILE A 1 510 ? -12.191 -35.319 37.238 1.00 31.61 ? 537 ILE A CG2 1 ATOM 4076 C CD1 . ILE A 1 510 ? -15.047 -36.129 37.693 1.00 30.67 ? 537 ILE A CD1 1 ATOM 4077 N N . ALA A 1 511 ? -9.121 -37.522 37.000 1.00 44.22 ? 538 ALA A N 1 ATOM 4078 C CA . ALA A 1 511 ? -7.739 -37.253 37.386 1.00 40.33 ? 538 ALA A CA 1 ATOM 4079 C C . ALA A 1 511 ? -7.415 -35.768 37.364 1.00 43.49 ? 538 ALA A C 1 ATOM 4080 O O . ALA A 1 511 ? -7.042 -35.218 36.327 1.00 38.12 ? 538 ALA A O 1 ATOM 4081 C CB . ALA A 1 511 ? -6.778 -38.011 36.489 1.00 39.17 ? 538 ALA A CB 1 ATOM 4082 N N . LEU A 1 512 ? -7.554 -35.129 38.519 1.00 53.00 ? 539 LEU A N 1 ATOM 4083 C CA . LEU A 1 512 ? -7.196 -33.725 38.667 1.00 56.63 ? 539 LEU A CA 1 ATOM 4084 C C . LEU A 1 512 ? -5.933 -33.585 39.504 1.00 58.60 ? 539 LEU A C 1 ATOM 4085 O O . LEU A 1 512 ? -5.805 -34.225 40.549 1.00 62.51 ? 539 LEU A O 1 ATOM 4086 C CB . LEU A 1 512 ? -8.344 -32.941 39.298 1.00 51.96 ? 539 LEU A CB 1 ATOM 4087 C CG . LEU A 1 512 ? -9.528 -32.715 38.361 1.00 45.19 ? 539 LEU A CG 1 ATOM 4088 C CD1 . LEU A 1 512 ? -10.627 -31.957 39.075 1.00 36.70 ? 539 LEU A CD1 1 ATOM 4089 C CD2 . LEU A 1 512 ? -9.073 -31.972 37.110 1.00 44.75 ? 539 LEU A CD2 1 ATOM 4090 N N . PRO A 1 513 ? -4.986 -32.764 39.030 1.00 51.97 ? 540 PRO A N 1 ATOM 4091 C CA . PRO A 1 513 ? -3.717 -32.523 39.717 1.00 61.77 ? 540 PRO A CA 1 ATOM 4092 C C . PRO A 1 513 ? -3.684 -31.200 40.488 1.00 70.57 ? 540 PRO A C 1 ATOM 4093 O O . PRO A 1 513 ? -4.498 -30.309 40.241 1.00 68.86 ? 540 PRO A O 1 ATOM 4094 C CB . PRO A 1 513 ? -2.731 -32.457 38.557 1.00 57.42 ? 540 PRO A CB 1 ATOM 4095 C CG . PRO A 1 513 ? -3.524 -31.805 37.468 1.00 56.04 ? 540 PRO A CG 1 ATOM 4096 C CD . PRO A 1 513 ? -4.963 -32.239 37.653 1.00 50.53 ? 540 PRO A CD 1 ATOM 4097 N N . GLU A 1 514 ? -2.746 -31.090 41.427 1.00 72.85 ? 541 GLU A N 1 ATOM 4098 C CA . GLU A 1 514 ? -2.430 -29.820 42.070 1.00 71.59 ? 541 GLU A CA 1 ATOM 4099 C C . GLU A 1 514 ? -1.535 -29.054 41.107 1.00 72.71 ? 541 GLU A C 1 ATOM 4100 O O . GLU A 1 514 ? -0.485 -29.556 40.707 1.00 68.73 ? 541 GLU A O 1 ATOM 4101 C CB . GLU A 1 514 ? -1.700 -30.067 43.392 1.00 71.21 ? 541 GLU A CB 1 ATOM 4102 C CG . GLU A 1 514 ? -1.194 -28.811 44.099 1.00 76.34 ? 541 GLU A CG 1 ATOM 4103 C CD . GLU A 1 514 ? -0.321 -29.134 45.307 1.00 77.17 ? 541 GLU A CD 1 ATOM 4104 O OE1 . GLU A 1 514 ? -0.181 -30.330 45.641 1.00 74.13 ? 541 GLU A OE1 1 ATOM 4105 O OE2 . GLU A 1 514 ? 0.230 -28.196 45.922 1.00 71.69 1 541 GLU A OE2 1 ATOM 4106 N N . ASP A 1 515 ? -1.942 -27.849 40.719 1.00 72.87 ? 542 ASP A N 1 ATOM 4107 C CA . ASP A 1 515 ? -1.235 -27.147 39.649 1.00 74.62 ? 542 ASP A CA 1 ATOM 4108 C C . ASP A 1 515 ? -0.969 -25.662 39.883 1.00 74.35 ? 542 ASP A C 1 ATOM 4109 O O . ASP A 1 515 ? -1.379 -25.086 40.892 1.00 69.48 ? 542 ASP A O 1 ATOM 4110 C CB . ASP A 1 515 ? -1.966 -27.333 38.316 1.00 76.25 ? 542 ASP A CB 1 ATOM 4111 C CG . ASP A 1 515 ? -1.179 -28.181 37.339 1.00 76.79 ? 542 ASP A CG 1 ATOM 4112 O OD1 . ASP A 1 515 ? 0.050 -28.303 37.522 1.00 69.23 1 542 ASP A OD1 1 ATOM 4113 O OD2 . ASP A 1 515 ? -1.786 -28.720 36.388 1.00 76.12 ? 542 ASP A OD2 1 ATOM 4114 N N . VAL A 1 516 ? -0.263 -25.063 38.928 1.00 74.03 ? 543 VAL A N 1 ATOM 4115 C CA . VAL A 1 516 ? 0.064 -23.645 38.955 1.00 75.24 ? 543 VAL A CA 1 ATOM 4116 C C . VAL A 1 516 ? -0.300 -23.016 37.615 1.00 72.35 ? 543 VAL A C 1 ATOM 4117 O O . VAL A 1 516 ? 0.018 -23.561 36.556 1.00 67.67 ? 543 VAL A O 1 ATOM 4118 C CB . VAL A 1 516 ? 1.569 -23.411 39.215 1.00 80.22 ? 543 VAL A CB 1 ATOM 4119 C CG1 . VAL A 1 516 ? 1.886 -21.919 39.222 1.00 70.16 ? 543 VAL A CG1 1 ATOM 4120 C CG2 . VAL A 1 516 ? 1.999 -24.059 40.523 1.00 73.57 ? 543 VAL A CG2 1 ATOM 4121 N N . LEU A 1 526 ? -14.749 -19.124 30.741 1.00 49.75 ? 553 LEU A N 1 ATOM 4122 C CA . LEU A 1 526 ? -16.015 -19.446 31.397 1.00 52.23 ? 553 LEU A CA 1 ATOM 4123 C C . LEU A 1 526 ? -16.812 -20.522 30.655 1.00 54.21 ? 553 LEU A C 1 ATOM 4124 O O . LEU A 1 526 ? -17.374 -20.271 29.583 1.00 50.50 ? 553 LEU A O 1 ATOM 4125 C CB . LEU A 1 526 ? -16.872 -18.191 31.557 1.00 49.85 ? 553 LEU A CB 1 ATOM 4126 C CG . LEU A 1 526 ? -18.293 -18.491 32.037 1.00 54.83 ? 553 LEU A CG 1 ATOM 4127 C CD1 . LEU A 1 526 ? -18.269 -19.112 33.435 1.00 46.36 ? 553 LEU A CD1 1 ATOM 4128 C CD2 . LEU A 1 526 ? -19.164 -17.243 31.987 1.00 49.12 ? 553 LEU A CD2 1 ATOM 4129 N N . VAL A 1 527 ? -16.859 -21.719 31.235 1.00 44.57 ? 554 VAL A N 1 ATOM 4130 C CA . VAL A 1 527 ? -17.584 -22.846 30.653 1.00 39.51 ? 554 VAL A CA 1 ATOM 4131 C C . VAL A 1 527 ? -18.238 -23.675 31.755 1.00 42.90 ? 554 VAL A C 1 ATOM 4132 O O . VAL A 1 527 ? -17.589 -24.017 32.740 1.00 48.72 ? 554 VAL A O 1 ATOM 4133 C CB . VAL A 1 527 ? -16.638 -23.779 29.868 1.00 39.23 ? 554 VAL A CB 1 ATOM 4134 C CG1 . VAL A 1 527 ? -17.401 -24.983 29.334 1.00 34.72 ? 554 VAL A CG1 1 ATOM 4135 C CG2 . VAL A 1 527 ? -15.941 -23.033 28.734 1.00 42.50 ? 554 VAL A CG2 1 ATOM 4136 N N . HIS A 1 528 ? -19.517 -24.005 31.598 1.00 36.54 ? 555 HIS A N 1 ATOM 4137 C CA . HIS A 1 528 ? -20.200 -24.840 32.584 1.00 35.23 ? 555 HIS A CA 1 ATOM 4138 C C . HIS A 1 528 ? -20.183 -26.309 32.175 1.00 31.49 ? 555 HIS A C 1 ATOM 4139 O O . HIS A 1 528 ? -20.459 -26.635 31.025 1.00 36.28 ? 555 HIS A O 1 ATOM 4140 C CB . HIS A 1 528 ? -21.639 -24.371 32.782 1.00 36.36 ? 555 HIS A CB 1 ATOM 4141 C CG . HIS A 1 528 ? -21.753 -22.978 33.316 1.00 40.40 ? 555 HIS A CG 1 ATOM 4142 N ND1 . HIS A 1 528 ? -21.520 -21.861 32.541 1.00 41.32 ? 555 HIS A ND1 1 ATOM 4143 C CD2 . HIS A 1 528 ? -22.079 -22.520 34.547 1.00 38.91 ? 555 HIS A CD2 1 ATOM 4144 C CE1 . HIS A 1 528 ? -21.701 -20.776 33.271 1.00 38.41 ? 555 HIS A CE1 1 ATOM 4145 N NE2 . HIS A 1 528 ? -22.038 -21.148 34.493 1.00 44.65 ? 555 HIS A NE2 1 ATOM 4146 N N . VAL A 1 529 ? -19.864 -27.194 33.114 1.00 25.77 ? 556 VAL A N 1 ATOM 4147 C CA . VAL A 1 529 ? -19.789 -28.623 32.815 1.00 22.31 ? 556 VAL A CA 1 ATOM 4148 C C . VAL A 1 529 ? -20.553 -29.484 33.814 1.00 29.15 ? 556 VAL A C 1 ATOM 4149 O O . VAL A 1 529 ? -20.122 -29.661 34.954 1.00 28.46 ? 556 VAL A O 1 ATOM 4150 C CB . VAL A 1 529 ? -18.343 -29.112 32.793 1.00 26.11 ? 556 VAL A CB 1 ATOM 4151 C CG1 . VAL A 1 529 ? -18.303 -30.617 32.584 1.00 25.64 ? 556 VAL A CG1 1 ATOM 4152 C CG2 . VAL A 1 529 ? -17.557 -28.386 31.713 1.00 32.59 ? 556 VAL A CG2 1 ATOM 4153 N N . ASP A 1 530 ? -21.686 -30.026 33.381 1.00 31.43 ? 557 ASP A N 1 ATOM 4154 C CA . ASP A 1 530 ? -22.495 -30.872 34.246 1.00 29.22 ? 557 ASP A CA 1 ATOM 4155 C C . ASP A 1 530 ? -21.876 -32.262 34.299 1.00 26.60 ? 557 ASP A C 1 ATOM 4156 O O . ASP A 1 530 ? -21.579 -32.851 33.263 1.00 27.48 ? 557 ASP A O 1 ATOM 4157 C CB . ASP A 1 530 ? -23.937 -30.930 33.739 1.00 25.19 ? 557 ASP A CB 1 ATOM 4158 C CG . ASP A 1 530 ? -24.886 -31.559 34.743 1.00 31.15 ? 557 ASP A CG 1 ATOM 4159 O OD1 . ASP A 1 530 ? -24.500 -32.547 35.401 1.00 28.51 ? 557 ASP A OD1 1 ATOM 4160 O OD2 . ASP A 1 530 ? -26.024 -31.063 34.876 1.00 37.20 1 557 ASP A OD2 1 ATOM 4161 N N . LEU A 1 531 ? -21.683 -32.781 35.508 1.00 25.33 ? 558 LEU A N 1 ATOM 4162 C CA . LEU A 1 531 ? -21.037 -34.077 35.697 1.00 22.84 ? 558 LEU A CA 1 ATOM 4163 C C . LEU A 1 531 ? -21.882 -35.027 36.537 1.00 25.20 ? 558 LEU A C 1 ATOM 4164 O O . LEU A 1 531 ? -21.374 -36.020 37.056 1.00 24.79 ? 558 LEU A O 1 ATOM 4165 C CB . LEU A 1 531 ? -19.669 -33.902 36.358 1.00 23.18 ? 558 LEU A CB 1 ATOM 4166 C CG . LEU A 1 531 ? -18.606 -33.111 35.594 1.00 27.76 ? 558 LEU A CG 1 ATOM 4167 C CD1 . LEU A 1 531 ? -17.353 -32.925 36.435 1.00 21.63 ? 558 LEU A CD1 1 ATOM 4168 C CD2 . LEU A 1 531 ? -18.265 -33.808 34.295 1.00 33.03 ? 558 LEU A CD2 1 ATOM 4169 N N . ASN A 1 532 ? -23.169 -34.724 36.670 1.00 25.44 ? 559 ASN A N 1 ATOM 4170 C CA . ASN A 1 532 ? -24.055 -35.533 37.500 1.00 30.78 ? 559 ASN A CA 1 ATOM 4171 C C . ASN A 1 532 ? -24.265 -36.950 36.963 1.00 32.85 ? 559 ASN A C 1 ATOM 4172 O O . ASN A 1 532 ? -24.123 -37.200 35.766 1.00 32.04 ? 559 ASN A O 1 ATOM 4173 C CB . ASN A 1 532 ? -25.406 -34.840 37.673 1.00 35.53 ? 559 ASN A CB 1 ATOM 4174 C CG . ASN A 1 532 ? -25.277 -33.440 38.230 1.00 36.51 ? 559 ASN A CG 1 ATOM 4175 O OD1 . ASN A 1 532 ? -24.234 -32.804 38.107 1.00 32.31 ? 559 ASN A OD1 1 ATOM 4176 N ND2 . ASN A 1 532 ? -26.345 -32.948 38.843 1.00 45.21 ? 559 ASN A ND2 1 ATOM 4177 N N . ASP A 1 533 ? -24.604 -37.866 37.865 1.00 36.89 ? 560 ASP A N 1 ATOM 4178 C CA . ASP A 1 533 ? -24.892 -39.259 37.517 1.00 36.49 ? 560 ASP A CA 1 ATOM 4179 C C . ASP A 1 533 ? -23.723 -39.960 36.830 1.00 37.87 ? 560 ASP A C 1 ATOM 4180 O O . ASP A 1 533 ? -23.750 -40.199 35.626 1.00 31.83 ? 560 ASP A O 1 ATOM 4181 C CB . ASP A 1 533 ? -26.142 -39.348 36.647 1.00 27.92 ? 560 ASP A CB 1 ATOM 4182 C CG . ASP A 1 533 ? -27.279 -38.516 37.185 1.00 34.10 ? 560 ASP A CG 1 ATOM 4183 O OD1 . ASP A 1 533 ? -28.061 -39.040 38.006 1.00 38.03 ? 560 ASP A OD1 1 ATOM 4184 O OD2 . ASP A 1 533 ? -27.392 -37.337 36.784 1.00 36.67 1 560 ASP A OD2 1 ATOM 4185 N N . ASN A 1 534 ? -22.697 -40.293 37.603 1.00 41.27 ? 561 ASN A N 1 ATOM 4186 C CA . ASN A 1 534 ? -21.537 -40.971 37.048 1.00 35.63 ? 561 ASN A CA 1 ATOM 4187 C C . ASN A 1 534 ? -20.980 -42.059 37.952 1.00 38.97 ? 561 ASN A C 1 ATOM 4188 O O . ASN A 1 534 ? -21.072 -41.963 39.174 1.00 39.39 ? 561 ASN A O 1 ATOM 4189 C CB . ASN A 1 534 ? -20.461 -39.961 36.669 1.00 31.35 ? 561 ASN A CB 1 ATOM 4190 C CG . ASN A 1 534 ? -20.673 -39.398 35.291 1.00 26.63 ? 561 ASN A CG 1 ATOM 4191 O OD1 . ASN A 1 534 ? -20.155 -39.927 34.314 1.00 28.55 ? 561 ASN A OD1 1 ATOM 4192 N ND2 . ASN A 1 534 ? -21.457 -38.333 35.197 1.00 23.47 ? 561 ASN A ND2 1 ATOM 4193 N N . PRO A 1 535 ? -20.413 -43.111 37.341 1.00 42.52 ? 562 PRO A N 1 ATOM 4194 C CA . PRO A 1 535 ? -19.896 -44.292 38.040 1.00 41.46 ? 562 PRO A CA 1 ATOM 4195 C C . PRO A 1 535 ? -18.570 -44.043 38.749 1.00 40.47 ? 562 PRO A C 1 ATOM 4196 O O . PRO A 1 535 ? -17.746 -44.950 38.823 1.00 42.94 ? 562 PRO A O 1 ATOM 4197 C CB . PRO A 1 535 ? -19.682 -45.305 36.905 1.00 45.22 ? 562 PRO A CB 1 ATOM 4198 C CG . PRO A 1 535 ? -20.459 -44.777 35.740 1.00 44.16 ? 562 PRO A CG 1 ATOM 4199 C CD . PRO A 1 535 ? -20.391 -43.297 35.880 1.00 43.99 ? 562 PRO A CD 1 ATOM 4200 N N . LEU A 1 536 ? -18.377 -42.836 39.267 1.00 46.33 ? 563 LEU A N 1 ATOM 4201 C CA . LEU A 1 536 ? -17.119 -42.454 39.899 1.00 44.21 ? 563 LEU A CA 1 ATOM 4202 C C . LEU A 1 536 ? -16.738 -43.378 41.048 1.00 43.36 ? 563 LEU A C 1 ATOM 4203 O O . LEU A 1 536 ? -17.544 -43.622 41.948 1.00 41.77 ? 563 LEU A O 1 ATOM 4204 C CB . LEU A 1 536 ? -17.208 -41.019 40.417 1.00 39.29 ? 563 LEU A CB 1 ATOM 4205 C CG . LEU A 1 536 ? -15.916 -40.211 40.353 1.00 35.71 ? 563 LEU A CG 1 ATOM 4206 C CD1 . LEU A 1 536 ? -15.557 -39.931 38.908 1.00 34.81 ? 563 LEU A CD1 1 ATOM 4207 C CD2 . LEU A 1 536 ? -16.054 -38.917 41.132 1.00 41.27 ? 563 LEU A CD2 1 ATOM 4208 N N . VAL A 1 537 ? -15.514 -43.900 41.000 1.00 44.73 ? 564 VAL A N 1 ATOM 4209 C CA . VAL A 1 537 ? -14.939 -44.606 42.141 1.00 45.46 ? 564 VAL A CA 1 ATOM 4210 C C . VAL A 1 537 ? -14.249 -43.583 43.029 1.00 46.49 ? 564 VAL A C 1 ATOM 4211 O O . VAL A 1 537 ? -13.611 -42.653 42.535 1.00 44.16 ? 564 VAL A O 1 ATOM 4212 C CB . VAL A 1 537 ? -13.930 -45.707 41.726 1.00 43.97 ? 564 VAL A CB 1 ATOM 4213 C CG1 . VAL A 1 537 ? -14.603 -46.736 40.844 1.00 45.93 ? 564 VAL A CG1 1 ATOM 4214 C CG2 . VAL A 1 537 ? -12.711 -45.114 41.027 1.00 44.98 ? 564 VAL A CG2 1 ATOM 4215 N N . CYS A 1 538 ? -14.390 -43.740 44.340 1.00 48.27 ? 565 CYS A N 1 ATOM 4216 C CA . CYS A 1 538 ? -13.852 -42.752 45.268 1.00 46.58 ? 565 CYS A CA 1 ATOM 4217 C C . CYS A 1 538 ? -12.601 -43.224 46.003 1.00 44.36 ? 565 CYS A C 1 ATOM 4218 O O . CYS A 1 538 ? -12.549 -43.229 47.234 1.00 45.00 ? 565 CYS A O 1 ATOM 4219 C CB . CYS A 1 538 ? -14.930 -42.296 46.246 1.00 39.19 ? 565 CYS A CB 1 ATOM 4220 S SG . CYS A 1 538 ? -16.232 -41.351 45.441 1.00 30.46 ? 565 CYS A SG 1 ATOM 4221 N N . ASP A 1 539 ? -11.595 -43.619 45.230 1.00 36.02 ? 566 ASP A N 1 ATOM 4222 C CA . ASP A 1 539 ? -10.304 -43.978 45.786 1.00 36.86 ? 566 ASP A CA 1 ATOM 4223 C C . ASP A 1 539 ? -9.377 -42.774 45.716 1.00 34.11 ? 566 ASP A C 1 ATOM 4224 O O . ASP A 1 539 ? -9.797 -41.689 45.327 1.00 32.98 ? 566 ASP A O 1 ATOM 4225 C CB . ASP A 1 539 ? -9.708 -45.186 45.056 1.00 42.25 ? 566 ASP A CB 1 ATOM 4226 C CG . ASP A 1 539 ? -9.756 -45.044 43.547 1.00 47.60 ? 566 ASP A CG 1 ATOM 4227 O OD1 . ASP A 1 539 ? -9.906 -43.907 43.056 1.00 53.26 ? 566 ASP A OD1 1 ATOM 4228 O OD2 . ASP A 1 539 ? -9.635 -46.072 42.848 1.00 47.25 1 566 ASP A OD2 1 ATOM 4229 N N . CYS A 1 540 ? -8.117 -42.972 46.080 1.00 31.25 ? 567 CYS A N 1 ATOM 4230 C CA . CYS A 1 540 ? -7.174 -41.872 46.209 1.00 31.52 ? 567 CYS A CA 1 ATOM 4231 C C . CYS A 1 540 ? -6.839 -41.200 44.882 1.00 40.66 ? 567 CYS A C 1 ATOM 4232 O O . CYS A 1 540 ? -6.142 -40.184 44.859 1.00 41.50 ? 567 CYS A O 1 ATOM 4233 C CB . CYS A 1 540 ? -5.883 -42.369 46.842 1.00 34.87 ? 567 CYS A CB 1 ATOM 4234 S SG . CYS A 1 540 ? -4.850 -43.296 45.692 1.00 48.67 ? 567 CYS A SG 1 ATOM 4235 N N . THR A 1 541 ? -7.320 -41.766 43.778 1.00 41.24 ? 568 THR A N 1 ATOM 4236 C CA . THR A 1 541 ? -6.983 -41.237 42.456 1.00 42.69 ? 568 THR A CA 1 ATOM 4237 C C . THR A 1 541 ? -7.693 -39.922 42.149 1.00 40.53 ? 568 THR A C 1 ATOM 4238 O O . THR A 1 541 ? -7.201 -39.109 41.365 1.00 48.83 ? 568 THR A O 1 ATOM 4239 C CB . THR A 1 541 ? -7.260 -42.258 41.326 1.00 41.15 ? 568 THR A CB 1 ATOM 4240 O OG1 . THR A 1 541 ? -8.370 -43.088 41.684 1.00 41.55 ? 568 THR A OG1 1 ATOM 4241 C CG2 . THR A 1 541 ? -6.042 -43.137 41.086 1.00 45.60 ? 568 THR A CG2 1 ATOM 4242 N N . ILE A 1 542 ? -8.842 -39.708 42.776 1.00 33.44 ? 569 ILE A N 1 ATOM 4243 C CA . ILE A 1 542 ? -9.638 -38.522 42.501 1.00 34.08 ? 569 ILE A CA 1 ATOM 4244 C C . ILE A 1 542 ? -9.528 -37.501 43.625 1.00 37.66 ? 569 ILE A C 1 ATOM 4245 O O . ILE A 1 542 ? -10.430 -36.693 43.837 1.00 38.81 ? 569 ILE A O 1 ATOM 4246 C CB . ILE A 1 542 ? -11.110 -38.891 42.277 1.00 39.22 ? 569 ILE A CB 1 ATOM 4247 C CG1 . ILE A 1 542 ? -11.720 -39.476 43.553 1.00 41.13 ? 569 ILE A CG1 1 ATOM 4248 C CG2 . ILE A 1 542 ? -11.225 -39.891 41.139 1.00 42.06 ? 569 ILE A CG2 1 ATOM 4249 C CD1 . ILE A 1 542 ? -13.221 -39.680 43.478 1.00 35.27 ? 569 ILE A CD1 1 ATOM 4250 N N . LEU A 1 543 ? -8.403 -37.538 44.331 1.00 41.41 ? 570 LEU A N 1 ATOM 4251 C CA . LEU A 1 543 ? -8.170 -36.674 45.485 1.00 46.76 ? 570 LEU A CA 1 ATOM 4252 C C . LEU A 1 543 ? -8.424 -35.189 45.222 1.00 51.22 ? 570 LEU A C 1 ATOM 4253 O O . LEU A 1 543 ? -9.298 -34.585 45.844 1.00 50.32 ? 570 LEU A O 1 ATOM 4254 C CB . LEU A 1 543 ? -6.741 -36.849 45.990 1.00 46.63 ? 570 LEU A CB 1 ATOM 4255 C CG . LEU A 1 543 ? -6.315 -35.822 47.036 1.00 40.81 ? 570 LEU A CG 1 ATOM 4256 C CD1 . LEU A 1 543 ? -6.945 -36.146 48.377 1.00 39.33 ? 570 LEU A CD1 1 ATOM 4257 C CD2 . LEU A 1 543 ? -4.805 -35.764 47.132 1.00 37.11 ? 570 LEU A CD2 1 ATOM 4258 N N . TRP A 1 544 ? -7.658 -34.610 44.302 1.00 47.77 ? 571 TRP A N 1 ATOM 4259 C CA . TRP A 1 544 ? -7.716 -33.174 44.055 1.00 46.19 ? 571 TRP A CA 1 ATOM 4260 C C . TRP A 1 544 ? -9.061 -32.706 43.524 1.00 49.43 ? 571 TRP A C 1 ATOM 4261 O O . TRP A 1 544 ? -9.426 -31.541 43.685 1.00 50.09 ? 571 TRP A O 1 ATOM 4262 C CB . TRP A 1 544 ? -6.597 -32.740 43.113 1.00 48.89 ? 571 TRP A CB 1 ATOM 4263 C CG . TRP A 1 544 ? -5.250 -32.886 43.726 1.00 61.05 ? 571 TRP A CG 1 ATOM 4264 C CD1 . TRP A 1 544 ? -4.245 -33.714 43.319 1.00 61.72 ? 571 TRP A CD1 1 ATOM 4265 C CD2 . TRP A 1 544 ? -4.761 -32.198 44.883 1.00 65.30 ? 571 TRP A CD2 1 ATOM 4266 N NE1 . TRP A 1 544 ? -3.155 -33.575 44.144 1.00 61.38 ? 571 TRP A NE1 1 ATOM 4267 C CE2 . TRP A 1 544 ? -3.447 -32.650 45.113 1.00 67.09 ? 571 TRP A CE2 1 ATOM 4268 C CE3 . TRP A 1 544 ? -5.305 -31.239 45.744 1.00 59.40 ? 571 TRP A CE3 1 ATOM 4269 C CZ2 . TRP A 1 544 ? -2.670 -32.177 46.167 1.00 74.34 ? 571 TRP A CZ2 1 ATOM 4270 C CZ3 . TRP A 1 544 ? -4.533 -30.770 46.789 1.00 59.64 ? 571 TRP A CZ3 1 ATOM 4271 C CH2 . TRP A 1 544 ? -3.230 -31.239 46.993 1.00 69.53 ? 571 TRP A CH2 1 ATOM 4272 N N . PHE A 1 545 ? -9.798 -33.611 42.893 1.00 46.05 ? 572 PHE A N 1 ATOM 4273 C CA . PHE A 1 545 ? -11.129 -33.278 42.416 1.00 40.31 ? 572 PHE A CA 1 ATOM 4274 C C . PHE A 1 545 ? -12.046 -32.905 43.580 1.00 39.97 ? 572 PHE A C 1 ATOM 4275 O O . PHE A 1 545 ? -12.733 -31.887 43.533 1.00 42.79 ? 572 PHE A O 1 ATOM 4276 C CB . PHE A 1 545 ? -11.725 -34.424 41.593 1.00 39.11 ? 572 PHE A CB 1 ATOM 4277 C CG . PHE A 1 545 ? -13.187 -34.249 41.283 1.00 38.28 ? 572 PHE A CG 1 ATOM 4278 C CD1 . PHE A 1 545 ? -13.622 -33.192 40.501 1.00 33.99 ? 572 PHE A CD1 1 ATOM 4279 C CD2 . PHE A 1 545 ? -14.127 -35.140 41.777 1.00 35.69 ? 572 PHE A CD2 1 ATOM 4280 C CE1 . PHE A 1 545 ? -14.962 -33.022 40.222 1.00 25.57 ? 572 PHE A CE1 1 ATOM 4281 C CE2 . PHE A 1 545 ? -15.470 -34.976 41.498 1.00 33.19 ? 572 PHE A CE2 1 ATOM 4282 C CZ . PHE A 1 545 ? -15.886 -33.916 40.720 1.00 28.69 ? 572 PHE A CZ 1 ATOM 4283 N N . ILE A 1 546 ? -12.037 -33.716 44.632 1.00 37.63 ? 573 ILE A N 1 ATOM 4284 C CA . ILE A 1 546 ? -12.926 -33.495 45.772 1.00 46.46 ? 573 ILE A CA 1 ATOM 4285 C C . ILE A 1 546 ? -12.583 -32.204 46.517 1.00 49.08 ? 573 ILE A C 1 ATOM 4286 O O . ILE A 1 546 ? -13.468 -31.470 46.968 1.00 46.94 ? 573 ILE A O 1 ATOM 4287 C CB . ILE A 1 546 ? -12.925 -34.699 46.743 1.00 46.43 ? 573 ILE A CB 1 ATOM 4288 C CG1 . ILE A 1 546 ? -13.851 -35.792 46.224 1.00 44.45 ? 573 ILE A CG1 1 ATOM 4289 C CG2 . ILE A 1 546 ? -13.405 -34.292 48.130 1.00 44.45 ? 573 ILE A CG2 1 ATOM 4290 C CD1 . ILE A 1 546 ? -13.361 -36.492 44.995 1.00 45.34 ? 573 ILE A CD1 1 ATOM 4291 N N . GLN A 1 547 ? -11.293 -31.924 46.634 1.00 47.19 ? 574 GLN A N 1 ATOM 4292 C CA . GLN A 1 547 ? -10.860 -30.684 47.249 1.00 48.16 ? 574 GLN A CA 1 ATOM 4293 C C . GLN A 1 547 ? -11.359 -29.519 46.403 1.00 48.62 ? 574 GLN A C 1 ATOM 4294 O O . GLN A 1 547 ? -11.860 -28.529 46.933 1.00 51.61 ? 574 GLN A O 1 ATOM 4295 C CB . GLN A 1 547 ? -9.337 -30.656 47.386 1.00 52.15 ? 574 GLN A CB 1 ATOM 4296 C CG . GLN A 1 547 ? -8.758 -31.804 48.210 1.00 52.86 ? 574 GLN A CG 1 ATOM 4297 C CD . GLN A 1 547 ? -9.051 -31.682 49.698 1.00 48.53 ? 574 GLN A CD 1 ATOM 4298 O OE1 . GLN A 1 547 ? -10.198 -31.799 50.132 1.00 45.66 ? 574 GLN A OE1 1 ATOM 4299 N NE2 . GLN A 1 547 ? -8.008 -31.450 50.486 1.00 51.85 ? 574 GLN A NE2 1 ATOM 4300 N N . LEU A 1 548 ? -11.242 -29.662 45.086 1.00 47.84 ? 575 LEU A N 1 ATOM 4301 C CA . LEU A 1 548 ? -11.718 -28.647 44.149 1.00 46.52 ? 575 LEU A CA 1 ATOM 4302 C C . LEU A 1 548 ? -13.227 -28.452 44.239 1.00 37.65 ? 575 LEU A C 1 ATOM 4303 O O . LEU A 1 548 ? -13.719 -27.331 44.143 1.00 33.64 ? 575 LEU A O 1 ATOM 4304 C CB . LEU A 1 548 ? -11.321 -29.010 42.717 1.00 42.15 ? 575 LEU A CB 1 ATOM 4305 C CG . LEU A 1 548 ? -11.974 -28.197 41.596 1.00 42.68 ? 575 LEU A CG 1 ATOM 4306 C CD1 . LEU A 1 548 ? -11.719 -26.715 41.769 1.00 46.63 ? 575 LEU A CD1 1 ATOM 4307 C CD2 . LEU A 1 548 ? -11.475 -28.658 40.240 1.00 47.75 ? 575 LEU A CD2 1 ATOM 4308 N N . VAL A 1 549 ? -13.953 -29.549 44.413 1.00 38.37 ? 576 VAL A N 1 ATOM 4309 C CA . VAL A 1 549 ? -15.401 -29.497 44.572 1.00 41.88 ? 576 VAL A CA 1 ATOM 4310 C C . VAL A 1 549 ? -15.789 -28.581 45.728 1.00 47.92 ? 576 VAL A C 1 ATOM 4311 O O . VAL A 1 549 ? -16.709 -27.771 45.610 1.00 55.10 ? 576 VAL A O 1 ATOM 4312 C CB . VAL A 1 549 ? -15.994 -30.907 44.777 1.00 44.90 ? 576 VAL A CB 1 ATOM 4313 C CG1 . VAL A 1 549 ? -17.355 -30.837 45.455 1.00 44.95 ? 576 VAL A CG1 1 ATOM 4314 C CG2 . VAL A 1 549 ? -16.082 -31.637 43.447 1.00 38.77 ? 576 VAL A CG2 1 ATOM 4315 N N . ARG A 1 550 ? -15.077 -28.703 46.843 1.00 51.10 ? 577 ARG A N 1 ATOM 4316 C CA . ARG A 1 550 ? -15.257 -27.776 47.948 1.00 50.72 ? 577 ARG A CA 1 ATOM 4317 C C . ARG A 1 550 ? -14.370 -26.569 47.702 1.00 50.62 ? 577 ARG A C 1 ATOM 4318 O O . ARG A 1 550 ? -13.695 -26.494 46.678 1.00 50.49 ? 577 ARG A O 1 ATOM 4319 C CB . ARG A 1 550 ? -14.917 -28.442 49.279 1.00 54.74 ? 577 ARG A CB 1 ATOM 4320 C CG . ARG A 1 550 ? -15.805 -29.634 49.606 1.00 63.62 ? 577 ARG A CG 1 ATOM 4321 C CD . ARG A 1 550 ? -15.575 -30.114 51.025 1.00 71.44 ? 577 ARG A CD 1 ATOM 4322 N NE . ARG A 1 550 ? -14.154 -30.300 51.309 1.00 74.68 ? 577 ARG A NE 1 ATOM 4323 C CZ . ARG A 1 550 ? -13.502 -31.444 51.135 1.00 63.13 ? 577 ARG A CZ 1 ATOM 4324 N NH1 . ARG A 1 550 ? -14.145 -32.513 50.679 1.00 58.55 1 577 ARG A NH1 1 ATOM 4325 N NH2 . ARG A 1 550 ? -12.208 -31.518 51.420 1.00 52.52 ? 577 ARG A NH2 1 ATOM 4326 N N . GLY A 1 551 ? -14.370 -25.620 48.630 1.00 49.97 ? 578 GLY A N 1 ATOM 4327 C CA . GLY A 1 551 ? -13.590 -24.408 48.455 1.00 55.87 ? 578 GLY A CA 1 ATOM 4328 C C . GLY A 1 551 ? -12.098 -24.674 48.444 1.00 55.37 ? 578 GLY A C 1 ATOM 4329 O O . GLY A 1 551 ? -11.318 -23.868 47.933 1.00 51.73 ? 578 GLY A O 1 ATOM 4330 N N . VAL A 1 552 ? -11.723 -25.829 48.991 1.00 53.77 ? 579 VAL A N 1 ATOM 4331 C CA . VAL A 1 552 ? -10.335 -26.196 49.263 1.00 46.22 ? 579 VAL A CA 1 ATOM 4332 C C . VAL A 1 552 ? -9.354 -25.919 48.126 1.00 50.35 ? 579 VAL A C 1 ATOM 4333 O O . VAL A 1 552 ? -8.512 -25.031 48.238 1.00 56.00 ? 579 VAL A O 1 ATOM 4334 C CB . VAL A 1 552 ? -10.227 -27.683 49.650 1.00 49.58 ? 579 VAL A CB 1 ATOM 4335 C CG1 . VAL A 1 552 ? -8.872 -27.969 50.277 1.00 47.33 ? 579 VAL A CG1 1 ATOM 4336 C CG2 . VAL A 1 552 ? -11.356 -28.066 50.597 1.00 50.47 ? 579 VAL A CG2 1 ATOM 4337 N N . HIS A 1 553 ? -9.463 -26.677 47.039 1.00 54.39 ? 580 HIS A N 1 ATOM 4338 C CA . HIS A 1 553 ? -8.508 -26.578 45.936 1.00 55.29 ? 580 HIS A CA 1 ATOM 4339 C C . HIS A 1 553 ? -9.027 -25.676 44.818 1.00 56.40 ? 580 HIS A C 1 ATOM 4340 O O . HIS A 1 553 ? -10.176 -25.799 44.401 1.00 56.01 ? 580 HIS A O 1 ATOM 4341 C CB . HIS A 1 553 ? -8.193 -27.969 45.384 1.00 49.29 ? 580 HIS A CB 1 ATOM 4342 C CG . HIS A 1 553 ? -6.895 -28.050 44.641 1.00 58.38 ? 580 HIS A CG 1 ATOM 4343 N ND1 . HIS A 1 553 ? -5.716 -27.542 45.143 1.00 64.32 ? 580 HIS A ND1 1 ATOM 4344 C CD2 . HIS A 1 553 ? -6.587 -28.597 43.441 1.00 63.43 ? 580 HIS A CD2 1 ATOM 4345 C CE1 . HIS A 1 553 ? -4.740 -27.764 44.280 1.00 67.10 ? 580 HIS A CE1 1 ATOM 4346 N NE2 . HIS A 1 553 ? -5.242 -28.402 43.238 1.00 62.32 ? 580 HIS A NE2 1 ATOM 4347 N N . LYS A 1 554 ? -8.178 -24.764 44.347 1.00 57.74 ? 581 LYS A N 1 ATOM 4348 C CA . LYS A 1 554 ? -8.531 -23.848 43.261 1.00 57.00 ? 581 LYS A CA 1 ATOM 4349 C C . LYS A 1 554 ? -7.314 -23.538 42.381 1.00 59.09 ? 581 LYS A C 1 ATOM 4350 O O . LYS A 1 554 ? -6.875 -22.392 42.321 1.00 67.90 ? 581 LYS A O 1 ATOM 4351 C CB . LYS A 1 554 ? -9.100 -22.539 43.828 1.00 53.06 ? 581 LYS A CB 1 ATOM 4352 C CG . LYS A 1 554 ? -10.432 -22.665 44.573 1.00 55.71 ? 581 LYS A CG 1 ATOM 4353 C CD . LYS A 1 554 ? -11.594 -22.947 43.623 1.00 56.67 ? 581 LYS A CD 1 ATOM 4354 C CE . LYS A 1 554 ? -12.927 -23.003 44.364 1.00 54.40 ? 581 LYS A CE 1 ATOM 4355 N NZ . LYS A 1 554 ? -14.079 -23.230 43.440 1.00 47.26 1 581 LYS A NZ 1 ATOM 4356 N N . PRO A 1 555 ? -6.784 -24.553 41.676 1.00 58.05 ? 582 PRO A N 1 ATOM 4357 C CA . PRO A 1 555 ? -5.491 -24.475 40.980 1.00 63.13 ? 582 PRO A CA 1 ATOM 4358 C C . PRO A 1 555 ? -5.503 -23.756 39.629 1.00 62.44 ? 582 PRO A C 1 ATOM 4359 O O . PRO A 1 555 ? -5.331 -24.411 38.601 1.00 64.75 ? 582 PRO A O 1 ATOM 4360 C CB . PRO A 1 555 ? -5.144 -25.946 40.758 1.00 71.65 ? 582 PRO A CB 1 ATOM 4361 C CG . PRO A 1 555 ? -6.472 -26.599 40.574 1.00 67.57 ? 582 PRO A CG 1 ATOM 4362 C CD . PRO A 1 555 ? -7.426 -25.867 41.485 1.00 61.84 ? 582 PRO A CD 1 ATOM 4363 N N . GLN A 1 556 ? -5.677 -22.437 39.643 1.00 64.19 ? 583 GLN A N 1 ATOM 4364 C CA . GLN A 1 556 ? -5.660 -21.611 38.429 1.00 72.17 ? 583 GLN A CA 1 ATOM 4365 C C . GLN A 1 556 ? -6.818 -21.871 37.463 1.00 69.96 ? 583 GLN A C 1 ATOM 4366 O O . GLN A 1 556 ? -7.781 -21.102 37.424 1.00 70.08 ? 583 GLN A O 1 ATOM 4367 C CB . GLN A 1 556 ? -4.319 -21.712 37.688 1.00 75.28 ? 583 GLN A CB 1 ATOM 4368 C CG . GLN A 1 556 ? -3.642 -20.367 37.483 1.00 76.06 ? 583 GLN A CG 1 ATOM 4369 C CD . GLN A 1 556 ? -2.804 -20.305 36.218 1.00 66.54 ? 583 GLN A CD 1 ATOM 4370 O OE1 . GLN A 1 556 ? -2.584 -21.313 35.544 1.00 61.50 ? 583 GLN A OE1 1 ATOM 4371 N NE2 . GLN A 1 556 ? -2.337 -19.109 35.888 1.00 58.38 ? 583 GLN A NE2 1 ATOM 4372 N N . TYR A 1 557 ? -6.718 -22.946 36.683 1.00 66.92 ? 584 TYR A N 1 ATOM 4373 C CA . TYR A 1 557 ? -7.733 -23.268 35.678 1.00 70.42 ? 584 TYR A CA 1 ATOM 4374 C C . TYR A 1 557 ? -9.137 -23.398 36.272 1.00 61.19 ? 584 TYR A C 1 ATOM 4375 O O . TYR A 1 557 ? -10.132 -23.197 35.578 1.00 55.80 ? 584 TYR A O 1 ATOM 4376 C CB . TYR A 1 557 ? -7.359 -24.542 34.902 1.00 65.14 ? 584 TYR A CB 1 ATOM 4377 C CG . TYR A 1 557 ? -7.086 -25.746 35.774 1.00 61.75 ? 584 TYR A CG 1 ATOM 4378 C CD1 . TYR A 1 557 ? -8.127 -26.469 36.341 1.00 62.34 ? 584 TYR A CD1 1 ATOM 4379 C CD2 . TYR A 1 557 ? -5.785 -26.167 36.024 1.00 67.04 ? 584 TYR A CD2 1 ATOM 4380 C CE1 . TYR A 1 557 ? -7.884 -27.567 37.142 1.00 67.07 ? 584 TYR A CE1 1 ATOM 4381 C CE2 . TYR A 1 557 ? -5.531 -27.268 36.824 1.00 67.66 ? 584 TYR A CE2 1 ATOM 4382 C CZ . TYR A 1 557 ? -6.587 -27.964 37.379 1.00 67.09 ? 584 TYR A CZ 1 ATOM 4383 O OH . TYR A 1 557 ? -6.352 -29.061 38.174 1.00 62.66 ? 584 TYR A OH 1 ATOM 4384 N N . SER A 1 558 ? -9.193 -23.724 37.561 1.00 57.54 ? 585 SER A N 1 ATOM 4385 C CA . SER A 1 558 ? -10.446 -23.944 38.279 1.00 62.87 ? 585 SER A CA 1 ATOM 4386 C C . SER A 1 558 ? -11.503 -22.859 38.075 1.00 70.19 ? 585 SER A C 1 ATOM 4387 O O . SER A 1 558 ? -12.693 -23.156 37.964 1.00 65.13 ? 585 SER A O 1 ATOM 4388 C CB . SER A 1 558 ? -10.167 -24.090 39.776 1.00 61.62 ? 585 SER A CB 1 ATOM 4389 O OG . SER A 1 558 ? -11.346 -23.866 40.531 1.00 59.84 ? 585 SER A OG 1 ATOM 4390 N N . ARG A 1 559 ? -11.069 -21.604 38.033 1.00 72.34 ? 586 ARG A N 1 ATOM 4391 C CA . ARG A 1 559 ? -12.002 -20.485 37.979 1.00 68.39 ? 586 ARG A CA 1 ATOM 4392 C C . ARG A 1 559 ? -12.530 -20.245 36.570 1.00 60.49 ? 586 ARG A C 1 ATOM 4393 O O . ARG A 1 559 ? -13.536 -19.557 36.388 1.00 46.93 ? 586 ARG A O 1 ATOM 4394 C CB . ARG A 1 559 ? -11.341 -19.218 38.528 1.00 78.79 ? 586 ARG A CB 1 ATOM 4395 C CG . ARG A 1 559 ? -10.811 -19.363 39.949 1.00 73.69 ? 586 ARG A CG 1 ATOM 4396 C CD . ARG A 1 559 ? -9.978 -18.157 40.356 1.00 74.35 ? 586 ARG A CD 1 ATOM 4397 N NE . ARG A 1 559 ? -10.763 -16.925 40.358 1.00 82.08 ? 586 ARG A NE 1 ATOM 4398 C CZ . ARG A 1 559 ? -10.274 -15.729 40.668 1.00 78.44 ? 586 ARG A CZ 1 ATOM 4399 N NH1 . ARG A 1 559 ? -11.064 -14.662 40.645 1.00 69.35 1 586 ARG A NH1 1 ATOM 4400 N NH2 . ARG A 1 559 ? -8.997 -15.598 41.004 1.00 70.50 ? 586 ARG A NH2 1 ATOM 4401 N N . GLN A 1 560 ? -11.850 -20.819 35.579 1.00 65.68 ? 587 GLN A N 1 ATOM 4402 C CA . GLN A 1 560 ? -12.239 -20.646 34.179 1.00 69.03 ? 587 GLN A CA 1 ATOM 4403 C C . GLN A 1 560 ? -13.311 -21.641 33.709 1.00 63.04 ? 587 GLN A C 1 ATOM 4404 O O . GLN A 1 560 ? -13.838 -21.523 32.599 1.00 53.76 ? 587 GLN A O 1 ATOM 4405 C CB . GLN A 1 560 ? -11.012 -20.671 33.263 1.00 53.95 ? 587 GLN A CB 1 ATOM 4406 C CG . GLN A 1 560 ? -10.190 -19.397 33.337 1.00 47.69 ? 587 GLN A CG 1 ATOM 4407 C CD . GLN A 1 560 ? -9.181 -19.288 32.216 1.00 62.30 ? 587 GLN A CD 1 ATOM 4408 O OE1 . GLN A 1 560 ? -8.381 -20.198 31.995 1.00 66.92 ? 587 GLN A OE1 1 ATOM 4409 N NE2 . GLN A 1 560 ? -9.217 -18.173 31.495 1.00 62.97 ? 587 GLN A NE2 1 ATOM 4410 N N . PHE A 1 561 ? -13.623 -22.620 34.555 1.00 55.62 ? 588 PHE A N 1 ATOM 4411 C CA . PHE A 1 561 ? -14.794 -23.463 34.340 1.00 45.75 ? 588 PHE A CA 1 ATOM 4412 C C . PHE A 1 561 ? -15.625 -23.583 35.615 1.00 48.00 ? 588 PHE A C 1 ATOM 4413 O O . PHE A 1 561 ? -15.102 -23.426 36.717 1.00 45.23 ? 588 PHE A O 1 ATOM 4414 C CB . PHE A 1 561 ? -14.431 -24.840 33.755 1.00 42.59 ? 588 PHE A CB 1 ATOM 4415 C CG . PHE A 1 561 ? -13.493 -25.662 34.607 1.00 44.30 ? 588 PHE A CG 1 ATOM 4416 C CD1 . PHE A 1 561 ? -13.868 -26.108 35.864 1.00 44.33 ? 588 PHE A CD1 1 ATOM 4417 C CD2 . PHE A 1 561 ? -12.251 -26.034 34.121 1.00 41.45 ? 588 PHE A CD2 1 ATOM 4418 C CE1 . PHE A 1 561 ? -13.015 -26.876 36.633 1.00 43.39 ? 588 PHE A CE1 1 ATOM 4419 C CE2 . PHE A 1 561 ? -11.395 -26.804 34.886 1.00 42.04 ? 588 PHE A CE2 1 ATOM 4420 C CZ . PHE A 1 561 ? -11.779 -27.225 36.143 1.00 40.20 ? 588 PHE A CZ 1 ATOM 4421 N N . LYS A 1 562 ? -16.918 -23.853 35.461 1.00 46.92 ? 589 LYS A N 1 ATOM 4422 C CA . LYS A 1 562 ? -17.812 -23.972 36.606 1.00 42.72 ? 589 LYS A CA 1 ATOM 4423 C C . LYS A 1 562 ? -18.530 -25.318 36.598 1.00 44.18 ? 589 LYS A C 1 ATOM 4424 O O . LYS A 1 562 ? -19.511 -25.513 35.874 1.00 45.03 ? 589 LYS A O 1 ATOM 4425 C CB . LYS A 1 562 ? -18.818 -22.818 36.633 1.00 44.64 ? 589 LYS A CB 1 ATOM 4426 C CG . LYS A 1 562 ? -19.393 -22.535 38.018 1.00 54.59 ? 589 LYS A CG 1 ATOM 4427 C CD . LYS A 1 562 ? -20.706 -23.268 38.256 1.00 56.70 ? 589 LYS A CD 1 ATOM 4428 C CE . LYS A 1 562 ? -21.016 -23.382 39.742 1.00 53.92 ? 589 LYS A CE 1 ATOM 4429 N NZ . LYS A 1 562 ? -20.076 -24.315 40.421 1.00 38.13 1 589 LYS A NZ 1 ATOM 4430 N N . LEU A 1 563 ? -18.032 -26.240 37.413 1.00 35.87 ? 590 LEU A N 1 ATOM 4431 C CA . LEU A 1 563 ? -18.542 -27.605 37.448 1.00 33.98 ? 590 LEU A CA 1 ATOM 4432 C C . LEU A 1 563 ? -19.872 -27.715 38.176 1.00 37.37 ? 590 LEU A C 1 ATOM 4433 O O . LEU A 1 563 ? -20.015 -27.217 39.290 1.00 46.00 ? 590 LEU A O 1 ATOM 4434 C CB . LEU A 1 563 ? -17.527 -28.520 38.134 1.00 33.14 ? 590 LEU A CB 1 ATOM 4435 C CG . LEU A 1 563 ? -16.556 -29.314 37.261 1.00 29.87 ? 590 LEU A CG 1 ATOM 4436 C CD1 . LEU A 1 563 ? -16.153 -28.523 36.039 1.00 24.78 ? 590 LEU A CD1 1 ATOM 4437 C CD2 . LEU A 1 563 ? -15.332 -29.704 38.073 1.00 34.34 ? 590 LEU A CD2 1 ATOM 4438 N N . ARG A 1 564 ? -20.846 -28.366 37.546 1.00 33.29 ? 591 ARG A N 1 ATOM 4439 C CA . ARG A 1 564 ? -22.045 -28.787 38.263 1.00 38.81 ? 591 ARG A CA 1 ATOM 4440 C C . ARG A 1 564 ? -21.864 -30.233 38.675 1.00 34.42 ? 591 ARG A C 1 ATOM 4441 O O . ARG A 1 564 ? -21.674 -31.100 37.827 1.00 36.19 ? 591 ARG A O 1 ATOM 4442 C CB . ARG A 1 564 ? -23.304 -28.652 37.411 1.00 39.03 ? 591 ARG A CB 1 ATOM 4443 C CG . ARG A 1 564 ? -24.498 -29.367 38.030 1.00 41.68 ? 591 ARG A CG 1 ATOM 4444 C CD . ARG A 1 564 ? -25.801 -28.969 37.371 1.00 51.63 ? 591 ARG A CD 1 ATOM 4445 N NE . ARG A 1 564 ? -26.094 -27.550 37.553 1.00 63.20 ? 591 ARG A NE 1 ATOM 4446 C CZ . ARG A 1 564 ? -27.204 -26.957 37.124 1.00 67.08 ? 591 ARG A CZ 1 ATOM 4447 N NH1 . ARG A 1 564 ? -28.130 -27.663 36.487 1.00 77.14 1 591 ARG A NH1 1 ATOM 4448 N NH2 . ARG A 1 564 ? -27.389 -25.660 37.331 1.00 56.94 ? 591 ARG A NH2 1 ATOM 4449 N N . THR A 1 565 ? -21.914 -30.495 39.975 1.00 35.91 ? 592 THR A N 1 ATOM 4450 C CA . THR A 1 565 ? -21.573 -31.814 40.494 1.00 38.28 ? 592 THR A CA 1 ATOM 4451 C C . THR A 1 565 ? -22.551 -32.285 41.564 1.00 39.25 ? 592 THR A C 1 ATOM 4452 O O . THR A 1 565 ? -22.321 -33.306 42.213 1.00 35.15 ? 592 THR A O 1 ATOM 4453 C CB . THR A 1 565 ? -20.152 -31.817 41.095 1.00 41.83 ? 592 THR A CB 1 ATOM 4454 O OG1 . THR A 1 565 ? -20.065 -30.828 42.130 1.00 36.91 ? 592 THR A OG1 1 ATOM 4455 C CG2 . THR A 1 565 ? -19.111 -31.510 40.026 1.00 35.12 ? 592 THR A CG2 1 ATOM 4456 N N . ASP A 1 566 ? -23.644 -31.543 41.730 1.00 41.16 ? 593 ASP A N 1 ATOM 4457 C CA . ASP A 1 566 ? -24.592 -31.773 42.820 1.00 41.07 ? 593 ASP A CA 1 ATOM 4458 C C . ASP A 1 566 ? -25.136 -33.196 42.881 1.00 45.20 ? 593 ASP A C 1 ATOM 4459 O O . ASP A 1 566 ? -25.478 -33.684 43.956 1.00 47.99 ? 593 ASP A O 1 ATOM 4460 C CB . ASP A 1 566 ? -25.749 -30.762 42.768 1.00 55.43 ? 593 ASP A CB 1 ATOM 4461 C CG . ASP A 1 566 ? -26.672 -30.976 41.574 1.00 54.23 ? 593 ASP A CG 1 ATOM 4462 O OD1 . ASP A 1 566 ? -26.303 -30.562 40.452 1.00 52.32 ? 593 ASP A OD1 1 ATOM 4463 O OD2 . ASP A 1 566 ? -27.774 -31.542 41.763 1.00 45.32 1 593 ASP A OD2 1 ATOM 4464 N N . ARG A 1 567 ? -25.217 -33.859 41.731 1.00 46.96 ? 594 ARG A N 1 ATOM 4465 C CA . ARG A 1 567 ? -25.676 -35.244 41.692 1.00 47.13 ? 594 ARG A CA 1 ATOM 4466 C C . ARG A 1 567 ? -24.607 -36.202 41.166 1.00 44.98 ? 594 ARG A C 1 ATOM 4467 O O . ARG A 1 567 ? -24.904 -37.131 40.416 1.00 42.68 ? 594 ARG A O 1 ATOM 4468 C CB . ARG A 1 567 ? -26.973 -35.377 40.888 1.00 46.87 ? 594 ARG A CB 1 ATOM 4469 C CG . ARG A 1 567 ? -28.213 -34.881 41.617 1.00 49.23 ? 594 ARG A CG 1 ATOM 4470 C CD . ARG A 1 567 ? -29.469 -35.158 40.805 1.00 56.52 ? 594 ARG A CD 1 ATOM 4471 N NE . ARG A 1 567 ? -29.451 -34.460 39.523 1.00 54.41 ? 594 ARG A NE 1 ATOM 4472 C CZ . ARG A 1 567 ? -30.013 -33.273 39.314 1.00 61.16 ? 594 ARG A CZ 1 ATOM 4473 N NH1 . ARG A 1 567 ? -29.947 -32.708 38.116 1.00 60.69 1 594 ARG A NH1 1 ATOM 4474 N NH2 . ARG A 1 567 ? -30.642 -32.651 40.303 1.00 65.21 ? 594 ARG A NH2 1 ATOM 4475 N N . LEU A 1 568 ? -23.361 -35.967 41.565 1.00 47.83 ? 595 LEU A N 1 ATOM 4476 C CA . LEU A 1 568 ? -22.283 -36.911 41.300 1.00 50.60 ? 595 LEU A CA 1 ATOM 4477 C C . LEU A 1 568 ? -22.091 -37.767 42.553 1.00 51.42 ? 595 LEU A C 1 ATOM 4478 O O . LEU A 1 568 ? -21.830 -37.243 43.633 1.00 52.06 ? 595 LEU A O 1 ATOM 4479 C CB . LEU A 1 568 ? -20.995 -36.165 40.952 1.00 45.44 ? 595 LEU A CB 1 ATOM 4480 C CG . LEU A 1 568 ? -20.030 -36.819 39.958 1.00 45.30 ? 595 LEU A CG 1 ATOM 4481 C CD1 . LEU A 1 568 ? -18.813 -35.929 39.735 1.00 33.81 ? 595 LEU A CD1 1 ATOM 4482 C CD2 . LEU A 1 568 ? -19.605 -38.215 40.407 1.00 46.25 ? 595 LEU A CD2 1 ATOM 4483 N N . VAL A 1 569 ? -22.227 -39.081 42.410 1.00 47.32 ? 596 VAL A N 1 ATOM 4484 C CA . VAL A 1 569 ? -22.230 -39.970 43.567 1.00 42.55 ? 596 VAL A CA 1 ATOM 4485 C C . VAL A 1 569 ? -21.253 -41.135 43.402 1.00 51.95 ? 596 VAL A C 1 ATOM 4486 O O . VAL A 1 569 ? -21.149 -41.718 42.323 1.00 57.88 ? 596 VAL A O 1 ATOM 4487 C CB . VAL A 1 569 ? -23.657 -40.506 43.843 1.00 44.46 ? 596 VAL A CB 1 ATOM 4488 C CG1 . VAL A 1 569 ? -23.635 -41.638 44.848 1.00 45.12 ? 596 VAL A CG1 1 ATOM 4489 C CG2 . VAL A 1 569 ? -24.560 -39.385 44.326 1.00 43.61 ? 596 VAL A CG2 1 ATOM 4490 N N . CYS A 1 570 ? -20.536 -41.458 44.476 1.00 52.87 ? 597 CYS A N 1 ATOM 4491 C CA . CYS A 1 570 ? -19.586 -42.567 44.484 1.00 47.10 ? 597 CYS A CA 1 ATOM 4492 C C . CYS A 1 570 ? -20.276 -43.920 44.335 1.00 52.26 ? 597 CYS A C 1 ATOM 4493 O O . CYS A 1 570 ? -21.211 -44.243 45.072 1.00 50.20 ? 597 CYS A O 1 ATOM 4494 C CB . CYS A 1 570 ? -18.777 -42.563 45.781 1.00 43.08 ? 597 CYS A CB 1 ATOM 4495 S SG . CYS A 1 570 ? -18.073 -40.965 46.217 1.00 43.70 ? 597 CYS A SG 1 ATOM 4496 N N . SER A 1 571 ? -19.798 -44.712 43.382 1.00 54.88 ? 598 SER A N 1 ATOM 4497 C CA . SER A 1 571 ? -20.318 -46.055 43.167 1.00 55.17 ? 598 SER A CA 1 ATOM 4498 C C . SER A 1 571 ? -19.567 -47.044 44.045 1.00 49.11 ? 598 SER A C 1 ATOM 4499 O O . SER A 1 571 ? -20.153 -47.954 44.625 1.00 47.51 ? 598 SER A O 1 ATOM 4500 C CB . SER A 1 571 ? -20.167 -46.444 41.698 1.00 52.96 ? 598 SER A CB 1 ATOM 4501 O OG . SER A 1 571 ? -20.765 -45.469 40.865 1.00 55.39 ? 598 SER A OG 1 ATOM 4502 N N . GLN A 1 572 ? -18.257 -46.856 44.129 1.00 45.99 ? 599 GLN A N 1 ATOM 4503 C CA . GLN A 1 572 ? -17.416 -47.687 44.970 1.00 48.98 ? 599 GLN A CA 1 ATOM 4504 C C . GLN A 1 572 ? -16.374 -46.808 45.651 1.00 52.70 ? 599 GLN A C 1 ATOM 4505 O O . GLN A 1 572 ? -15.990 -45.771 45.106 1.00 44.79 ? 599 GLN A O 1 ATOM 4506 C CB . GLN A 1 572 ? -16.753 -48.785 44.135 1.00 51.78 ? 599 GLN A CB 1 ATOM 4507 C CG . GLN A 1 572 ? -17.699 -49.906 43.732 1.00 51.63 ? 599 GLN A CG 1 ATOM 4508 C CD . GLN A 1 572 ? -17.010 -50.997 42.932 1.00 60.19 ? 599 GLN A CD 1 ATOM 4509 O OE1 . GLN A 1 572 ? -16.018 -50.747 42.241 1.00 48.76 ? 599 GLN A OE1 1 ATOM 4510 N NE2 . GLN A 1 572 ? -17.533 -52.218 43.023 1.00 56.34 ? 599 GLN A NE2 1 ATOM 4511 N N . PRO A 1 573 ? -15.919 -47.208 46.852 1.00 53.26 ? 600 PRO A N 1 ATOM 4512 C CA . PRO A 1 573 ? -16.305 -48.426 47.578 1.00 49.58 ? 600 PRO A CA 1 ATOM 4513 C C . PRO A 1 573 ? -17.616 -48.318 48.363 1.00 49.21 ? 600 PRO A C 1 ATOM 4514 O O . PRO A 1 573 ? -18.215 -47.244 48.465 1.00 40.48 ? 600 PRO A O 1 ATOM 4515 C CB . PRO A 1 573 ? -15.140 -48.628 48.544 1.00 56.13 ? 600 PRO A CB 1 ATOM 4516 C CG . PRO A 1 573 ? -14.665 -47.253 48.823 1.00 53.94 ? 600 PRO A CG 1 ATOM 4517 C CD . PRO A 1 573 ? -14.841 -46.479 47.545 1.00 46.74 ? 600 PRO A CD 1 ATOM 4518 N N . ASN A 1 574 ? -18.031 -49.451 48.927 1.00 51.52 ? 601 ASN A N 1 ATOM 4519 C CA . ASN A 1 574 ? -19.315 -49.592 49.610 1.00 52.64 ? 601 ASN A CA 1 ATOM 4520 C C . ASN A 1 574 ? -19.449 -48.721 50.853 1.00 54.78 ? 601 ASN A C 1 ATOM 4521 O O . ASN A 1 574 ? -20.545 -48.546 51.387 1.00 56.91 ? 601 ASN A O 1 ATOM 4522 C CB . ASN A 1 574 ? -19.539 -51.056 49.994 1.00 58.31 ? 601 ASN A CB 1 ATOM 4523 C CG . ASN A 1 574 ? -19.248 -52.011 48.852 1.00 61.14 ? 601 ASN A CG 1 ATOM 4524 O OD1 . ASN A 1 574 ? -18.090 -52.237 48.495 1.00 58.00 ? 601 ASN A OD1 1 ATOM 4525 N ND2 . ASN A 1 574 ? -20.299 -52.587 48.281 1.00 60.60 ? 601 ASN A ND2 1 ATOM 4526 N N . VAL A 1 575 ? -18.330 -48.188 51.321 1.00 55.97 ? 602 VAL A N 1 ATOM 4527 C CA . VAL A 1 575 ? -18.341 -47.316 52.484 1.00 55.58 ? 602 VAL A CA 1 ATOM 4528 C C . VAL A 1 575 ? -18.832 -45.925 52.091 1.00 60.64 ? 602 VAL A C 1 ATOM 4529 O O . VAL A 1 575 ? -19.789 -45.407 52.672 1.00 55.11 ? 602 VAL A O 1 ATOM 4530 C CB . VAL A 1 575 ? -16.941 -47.201 53.094 1.00 54.13 ? 602 VAL A CB 1 ATOM 4531 C CG1 . VAL A 1 575 ? -17.037 -46.786 54.556 1.00 56.22 ? 602 VAL A CG1 1 ATOM 4532 C CG2 . VAL A 1 575 ? -16.196 -48.522 52.950 1.00 47.06 ? 602 VAL A CG2 1 ATOM 4533 N N . LEU A 1 576 ? -18.175 -45.335 51.094 1.00 59.38 ? 603 LEU A N 1 ATOM 4534 C CA . LEU A 1 576 ? -18.508 -43.994 50.620 1.00 49.35 ? 603 LEU A CA 1 ATOM 4535 C C . LEU A 1 576 ? -19.696 -44.010 49.674 1.00 51.67 ? 603 LEU A C 1 ATOM 4536 O O . LEU A 1 576 ? -20.260 -42.962 49.364 1.00 53.33 ? 603 LEU A O 1 ATOM 4537 C CB . LEU A 1 576 ? -17.317 -43.356 49.897 1.00 49.29 ? 603 LEU A CB 1 ATOM 4538 C CG . LEU A 1 576 ? -16.022 -43.064 50.660 1.00 55.91 ? 603 LEU A CG 1 ATOM 4539 C CD1 . LEU A 1 576 ? -15.113 -44.282 50.690 1.00 56.45 ? 603 LEU A CD1 1 ATOM 4540 C CD2 . LEU A 1 576 ? -15.297 -41.869 50.054 1.00 44.11 ? 603 LEU A CD2 1 ATOM 4541 N N . GLU A 1 577 ? -20.061 -45.201 49.209 1.00 56.77 ? 604 GLU A N 1 ATOM 4542 C CA . GLU A 1 577 ? -21.113 -45.354 48.210 1.00 55.42 ? 604 GLU A CA 1 ATOM 4543 C C . GLU A 1 577 ? -22.403 -44.645 48.599 1.00 48.37 ? 604 GLU A C 1 ATOM 4544 O O . GLU A 1 577 ? -22.789 -44.632 49.768 1.00 52.79 ? 604 GLU A O 1 ATOM 4545 C CB . GLU A 1 577 ? -21.403 -46.833 47.957 1.00 53.77 ? 604 GLU A CB 1 ATOM 4546 C CG . GLU A 1 577 ? -22.307 -47.078 46.763 1.00 55.17 ? 604 GLU A CG 1 ATOM 4547 C CD . GLU A 1 577 ? -23.453 -48.011 47.083 1.00 56.97 ? 604 GLU A CD 1 ATOM 4548 O OE1 . GLU A 1 577 ? -23.975 -48.653 46.146 1.00 55.25 ? 604 GLU A OE1 1 ATOM 4549 O OE2 . GLU A 1 577 ? -23.835 -48.097 48.270 1.00 54.45 1 604 GLU A OE2 1 ATOM 4550 N N . GLY A 1 578 ? -23.056 -44.047 47.611 1.00 48.96 ? 605 GLY A N 1 ATOM 4551 C CA . GLY A 1 578 ? -24.345 -43.418 47.822 1.00 62.52 ? 605 GLY A CA 1 ATOM 4552 C C . GLY A 1 578 ? -24.234 -41.981 48.289 1.00 55.47 ? 605 GLY A C 1 ATOM 4553 O O . GLY A 1 578 ? -25.246 -41.319 48.522 1.00 51.72 ? 605 GLY A O 1 ATOM 4554 N N . THR A 1 579 ? -23.003 -41.495 48.412 1.00 45.74 ? 606 THR A N 1 ATOM 4555 C CA . THR A 1 579 ? -22.767 -40.176 48.982 1.00 46.06 ? 606 THR A CA 1 ATOM 4556 C C . THR A 1 579 ? -22.121 -39.213 47.994 1.00 44.62 ? 606 THR A C 1 ATOM 4557 O O . THR A 1 579 ? -21.158 -39.568 47.318 1.00 46.70 ? 606 THR A O 1 ATOM 4558 C CB . THR A 1 579 ? -21.867 -40.269 50.214 1.00 55.02 ? 606 THR A CB 1 ATOM 4559 O OG1 . THR A 1 579 ? -20.535 -40.606 49.804 1.00 55.40 ? 606 THR A OG1 1 ATOM 4560 C CG2 . THR A 1 579 ? -22.395 -41.331 51.174 1.00 55.01 ? 606 THR A CG2 1 ATOM 4561 N N . PRO A 1 580 ? -22.654 -37.984 47.921 1.00 43.78 ? 607 PRO A N 1 ATOM 4562 C CA . PRO A 1 580 ? -22.192 -36.890 47.055 1.00 48.90 ? 607 PRO A CA 1 ATOM 4563 C C . PRO A 1 580 ? -20.734 -36.485 47.274 1.00 48.41 ? 607 PRO A C 1 ATOM 4564 O O . PRO A 1 580 ? -20.099 -36.907 48.240 1.00 49.48 ? 607 PRO A O 1 ATOM 4565 C CB . PRO A 1 580 ? -23.120 -35.735 47.432 1.00 51.06 ? 607 PRO A CB 1 ATOM 4566 C CG . PRO A 1 580 ? -24.360 -36.401 47.901 1.00 52.44 ? 607 PRO A CG 1 ATOM 4567 C CD . PRO A 1 580 ? -23.898 -37.630 48.625 1.00 46.97 ? 607 PRO A CD 1 ATOM 4568 N N . VAL A 1 581 ? -20.229 -35.648 46.373 1.00 47.01 ? 608 VAL A N 1 ATOM 4569 C CA . VAL A 1 581 ? -18.803 -35.356 46.284 1.00 51.22 ? 608 VAL A CA 1 ATOM 4570 C C . VAL A 1 581 ? -18.358 -34.233 47.222 1.00 55.87 ? 608 VAL A C 1 ATOM 4571 O O . VAL A 1 581 ? -17.212 -34.206 47.674 1.00 57.95 ? 608 VAL A O 1 ATOM 4572 C CB . VAL A 1 581 ? -18.409 -35.005 44.833 1.00 51.62 ? 608 VAL A CB 1 ATOM 4573 C CG1 . VAL A 1 581 ? -16.907 -34.874 44.704 1.00 54.75 ? 608 VAL A CG1 1 ATOM 4574 C CG2 . VAL A 1 581 ? -18.917 -36.066 43.879 1.00 42.38 ? 608 VAL A CG2 1 ATOM 4575 N N . ARG A 1 582 ? -19.265 -33.308 47.515 1.00 60.79 ? 609 ARG A N 1 ATOM 4576 C CA . ARG A 1 582 ? -18.951 -32.204 48.418 1.00 70.29 ? 609 ARG A CA 1 ATOM 4577 C C . ARG A 1 582 ? -18.924 -32.676 49.874 1.00 68.22 ? 609 ARG A C 1 ATOM 4578 O O . ARG A 1 582 ? -18.267 -32.068 50.723 1.00 66.73 ? 609 ARG A O 1 ATOM 4579 C CB . ARG A 1 582 ? -19.954 -31.056 48.233 1.00 79.21 ? 609 ARG A CB 1 ATOM 4580 C CG . ARG A 1 582 ? -19.662 -29.813 49.072 1.00 89.12 ? 609 ARG A CG 1 ATOM 4581 C CD . ARG A 1 582 ? -20.684 -28.701 48.833 1.00 103.26 ? 609 ARG A CD 1 ATOM 4582 N NE . ARG A 1 582 ? -20.434 -27.962 47.597 1.00 104.12 ? 609 ARG A NE 1 ATOM 4583 C CZ . ARG A 1 582 ? -21.054 -26.835 47.256 1.00 104.85 ? 609 ARG A CZ 1 ATOM 4584 N NH1 . ARG A 1 582 ? -21.969 -26.305 48.058 1.00 97.18 1 609 ARG A NH1 1 ATOM 4585 N NH2 . ARG A 1 582 ? -20.757 -26.234 46.113 1.00 112.40 ? 609 ARG A NH2 1 ATOM 4586 N N . GLN A 1 583 ? -19.624 -33.775 50.147 1.00 58.63 ? 610 GLN A N 1 ATOM 4587 C CA . GLN A 1 583 ? -19.753 -34.298 51.505 1.00 54.25 ? 610 GLN A CA 1 ATOM 4588 C C . GLN A 1 583 ? -18.498 -34.998 52.018 1.00 52.62 ? 610 GLN A C 1 ATOM 4589 O O . GLN A 1 583 ? -18.106 -34.816 53.171 1.00 59.22 ? 610 GLN A O 1 ATOM 4590 C CB . GLN A 1 583 ? -20.933 -35.265 51.593 1.00 53.19 ? 610 GLN A CB 1 ATOM 4591 C CG . GLN A 1 583 ? -22.289 -34.622 51.383 1.00 59.23 ? 610 GLN A CG 1 ATOM 4592 C CD . GLN A 1 583 ? -23.422 -35.630 51.441 1.00 64.57 ? 610 GLN A CD 1 ATOM 4593 O OE1 . GLN A 1 583 ? -23.217 -36.790 51.807 1.00 63.48 ? 610 GLN A OE1 1 ATOM 4594 N NE2 . GLN A 1 583 ? -24.624 -35.195 51.073 1.00 55.90 ? 610 GLN A NE2 1 ATOM 4595 N N . ILE A 1 584 ? -17.875 -35.807 51.170 1.00 43.76 ? 611 ILE A N 1 ATOM 4596 C CA . ILE A 1 584 ? -16.774 -36.650 51.617 1.00 43.09 ? 611 ILE A CA 1 ATOM 4597 C C . ILE A 1 584 ? -15.538 -35.847 52.013 1.00 44.72 ? 611 ILE A C 1 ATOM 4598 O O . ILE A 1 584 ? -15.400 -34.675 51.655 1.00 42.32 ? 611 ILE A O 1 ATOM 4599 C CB . ILE A 1 584 ? -16.405 -37.719 50.565 1.00 41.13 ? 611 ILE A CB 1 ATOM 4600 C CG1 . ILE A 1 584 ? -15.776 -37.080 49.334 1.00 37.48 ? 611 ILE A CG1 1 ATOM 4601 C CG2 . ILE A 1 584 ? -17.635 -38.514 50.155 1.00 50.23 ? 611 ILE A CG2 1 ATOM 4602 C CD1 . ILE A 1 584 ? -15.538 -38.069 48.233 1.00 35.05 ? 611 ILE A CD1 1 ATOM 4603 N N . GLU A 1 585 ? -14.657 -36.491 52.774 1.00 44.38 ? 612 GLU A N 1 ATOM 4604 C CA . GLU A 1 585 ? -13.402 -35.886 53.204 1.00 41.18 ? 612 GLU A CA 1 ATOM 4605 C C . GLU A 1 585 ? -12.211 -36.717 52.724 1.00 38.47 ? 612 GLU A C 1 ATOM 4606 O O . GLU A 1 585 ? -12.168 -37.930 52.929 1.00 42.00 ? 612 GLU A O 1 ATOM 4607 C CB . GLU A 1 585 ? -13.379 -35.718 54.723 1.00 41.99 ? 612 GLU A CB 1 ATOM 4608 C CG . GLU A 1 585 ? -14.316 -34.633 55.227 1.00 50.73 ? 612 GLU A CG 1 ATOM 4609 C CD . GLU A 1 585 ? -14.201 -34.409 56.720 1.00 64.33 ? 612 GLU A CD 1 ATOM 4610 O OE1 . GLU A 1 585 ? -13.886 -35.376 57.446 1.00 63.72 ? 612 GLU A OE1 1 ATOM 4611 O OE2 . GLU A 1 585 ? -14.421 -33.264 57.168 1.00 74.53 1 612 GLU A OE2 1 ATOM 4612 N N . PRO A 1 586 ? -11.233 -36.052 52.094 1.00 31.98 ? 613 PRO A N 1 ATOM 4613 C CA . PRO A 1 586 ? -10.129 -36.644 51.325 1.00 36.83 ? 613 PRO A CA 1 ATOM 4614 C C . PRO A 1 586 ? -9.314 -37.762 52.001 1.00 42.84 ? 613 PRO A C 1 ATOM 4615 O O . PRO A 1 586 ? -8.507 -38.410 51.329 1.00 44.06 ? 613 PRO A O 1 ATOM 4616 C CB . PRO A 1 586 ? -9.234 -35.434 51.011 1.00 37.60 ? 613 PRO A CB 1 ATOM 4617 C CG . PRO A 1 586 ? -9.675 -34.361 51.947 1.00 37.96 ? 613 PRO A CG 1 ATOM 4618 C CD . PRO A 1 586 ? -11.125 -34.587 52.153 1.00 33.46 ? 613 PRO A CD 1 ATOM 4619 N N . GLN A 1 587 ? -9.511 -37.992 53.294 1.00 44.61 ? 614 GLN A N 1 ATOM 4620 C CA . GLN A 1 587 ? -8.773 -39.050 53.978 1.00 44.48 ? 614 GLN A CA 1 ATOM 4621 C C . GLN A 1 587 ? -9.457 -40.395 53.804 1.00 41.31 ? 614 GLN A C 1 ATOM 4622 O O . GLN A 1 587 ? -8.889 -41.437 54.128 1.00 48.61 ? 614 GLN A O 1 ATOM 4623 C CB . GLN A 1 587 ? -8.592 -38.736 55.465 1.00 41.32 ? 614 GLN A CB 1 ATOM 4624 C CG . GLN A 1 587 ? -9.810 -38.133 56.135 1.00 36.65 ? 614 GLN A CG 1 ATOM 4625 C CD . GLN A 1 587 ? -9.875 -36.627 55.957 1.00 45.56 ? 614 GLN A CD 1 ATOM 4626 O OE1 . GLN A 1 587 ? -9.146 -36.059 55.142 1.00 44.33 ? 614 GLN A OE1 1 ATOM 4627 N NE2 . GLN A 1 587 ? -10.743 -35.971 56.723 1.00 45.33 ? 614 GLN A NE2 1 ATOM 4628 N N . THR A 1 588 ? -10.681 -40.368 53.294 1.00 30.68 ? 615 THR A N 1 ATOM 4629 C CA . THR A 1 588 ? -11.397 -41.600 53.010 1.00 37.42 ? 615 THR A CA 1 ATOM 4630 C C . THR A 1 588 ? -10.926 -42.119 51.664 1.00 37.50 ? 615 THR A C 1 ATOM 4631 O O . THR A 1 588 ? -10.968 -43.320 51.384 1.00 33.07 ? 615 THR A O 1 ATOM 4632 C CB . THR A 1 588 ? -12.913 -41.369 52.952 1.00 40.80 ? 615 THR A CB 1 ATOM 4633 O OG1 . THR A 1 588 ? -13.256 -40.221 53.738 1.00 41.03 ? 615 THR A OG1 1 ATOM 4634 C CG2 . THR A 1 588 ? -13.659 -42.593 53.472 1.00 36.28 ? 615 THR A CG2 1 ATOM 4635 N N . LEU A 1 589 ? -10.474 -41.192 50.830 1.00 37.20 ? 616 LEU A N 1 ATOM 4636 C CA . LEU A 1 589 ? -10.003 -41.533 49.501 1.00 38.66 ? 616 LEU A CA 1 ATOM 4637 C C . LEU A 1 589 ? -8.695 -42.306 49.600 1.00 37.81 ? 616 LEU A C 1 ATOM 4638 O O . LEU A 1 589 ? -7.606 -41.726 49.567 1.00 34.10 ? 616 LEU A O 1 ATOM 4639 C CB . LEU A 1 589 ? -9.838 -40.272 48.653 1.00 35.27 ? 616 LEU A CB 1 ATOM 4640 C CG . LEU A 1 589 ? -11.060 -39.352 48.645 1.00 25.97 ? 616 LEU A CG 1 ATOM 4641 C CD1 . LEU A 1 589 ? -10.840 -38.189 47.695 1.00 31.44 ? 616 LEU A CD1 1 ATOM 4642 C CD2 . LEU A 1 589 ? -12.310 -40.125 48.279 1.00 23.76 ? 616 LEU A CD2 1 ATOM 4643 N N . ILE A 1 590 ? -8.825 -43.621 49.736 1.00 36.69 ? 617 ILE A N 1 ATOM 4644 C CA . ILE A 1 590 ? -7.683 -44.512 49.855 1.00 35.17 ? 617 ILE A CA 1 ATOM 4645 C C . ILE A 1 590 ? -7.673 -45.517 48.710 1.00 32.77 ? 617 ILE A C 1 ATOM 4646 O O . ILE A 1 590 ? -8.723 -45.882 48.182 1.00 30.07 ? 617 ILE A O 1 ATOM 4647 C CB . ILE A 1 590 ? -7.715 -45.264 51.192 1.00 37.56 ? 617 ILE A CB 1 ATOM 4648 C CG1 . ILE A 1 590 ? -8.987 -46.102 51.298 1.00 41.44 ? 617 ILE A CG1 1 ATOM 4649 C CG2 . ILE A 1 590 ? -7.675 -44.289 52.345 1.00 39.98 ? 617 ILE A CG2 1 ATOM 4650 C CD1 . ILE A 1 590 ? -9.174 -46.759 52.648 1.00 41.05 ? 617 ILE A CD1 1 ATOM 4651 N N . CYS A 1 591 ? -6.481 -45.958 48.326 1.00 34.52 ? 618 CYS A N 1 ATOM 4652 C CA . CYS A 1 591 ? -6.335 -46.927 47.244 1.00 40.34 ? 618 CYS A CA 1 ATOM 4653 C C . CYS A 1 591 ? -5.635 -48.186 47.748 1.00 45.23 ? 618 CYS A C 1 ATOM 4654 O O . CYS A 1 591 ? -4.424 -48.174 47.972 1.00 48.34 ? 618 CYS A O 1 ATOM 4655 C CB . CYS A 1 591 ? -5.552 -46.321 46.076 1.00 33.19 ? 618 CYS A CB 1 ATOM 4656 S SG . CYS A 1 591 ? -6.230 -44.766 45.455 1.00 38.73 ? 618 CYS A SG 1 ATOM 4657 N N . PRO A 1 592 ? -6.401 -49.277 47.924 1.00 44.57 ? 619 PRO A N 1 ATOM 4658 C CA . PRO A 1 592 ? -5.922 -50.536 48.506 1.00 40.43 ? 619 PRO A CA 1 ATOM 4659 C C . PRO A 1 592 ? -4.609 -51.034 47.914 1.00 41.75 ? 619 PRO A C 1 ATOM 4660 O O . PRO A 1 592 ? -4.481 -51.145 46.696 1.00 34.69 ? 619 PRO A O 1 ATOM 4661 C CB . PRO A 1 592 ? -7.049 -51.513 48.179 1.00 31.81 ? 619 PRO A CB 1 ATOM 4662 C CG . PRO A 1 592 ? -8.265 -50.665 48.174 1.00 31.28 ? 619 PRO A CG 1 ATOM 4663 C CD . PRO A 1 592 ? -7.837 -49.341 47.598 1.00 40.87 ? 619 PRO A CD 1 ATOM 4664 N N . LEU A 1 593 ? -3.644 -51.309 48.788 1.00 49.23 ? 620 LEU A N 1 ATOM 4665 C CA . LEU A 1 593 ? -2.396 -51.947 48.395 1.00 52.34 ? 620 LEU A CA 1 ATOM 4666 C C . LEU A 1 593 ? -2.589 -53.457 48.496 1.00 57.02 ? 620 LEU A C 1 ATOM 4667 O O . LEU A 1 593 ? -2.932 -53.975 49.560 1.00 55.92 ? 620 LEU A O 1 ATOM 4668 C CB . LEU A 1 593 ? -1.243 -51.482 49.295 1.00 44.02 ? 620 LEU A CB 1 ATOM 4669 C CG . LEU A 1 593 ? 0.203 -51.649 48.800 1.00 36.05 ? 620 LEU A CG 1 ATOM 4670 C CD1 . LEU A 1 593 ? 1.149 -50.759 49.591 1.00 29.65 ? 620 LEU A CD1 1 ATOM 4671 C CD2 . LEU A 1 593 ? 0.674 -53.096 48.865 1.00 40.73 ? 620 LEU A CD2 1 ATOM 4672 N N . ASP A 1 594 ? -2.378 -54.155 47.383 1.00 59.09 ? 621 ASP A N 1 ATOM 4673 C CA . ASP A 1 594 ? -2.575 -55.601 47.332 1.00 59.61 ? 621 ASP A CA 1 ATOM 4674 C C . ASP A 1 594 ? -1.600 -56.341 48.245 1.00 59.89 ? 621 ASP A C 1 ATOM 4675 O O . ASP A 1 594 ? -0.463 -56.613 47.863 1.00 56.17 ? 621 ASP A O 1 ATOM 4676 C CB . ASP A 1 594 ? -2.438 -56.112 45.894 1.00 74.59 ? 621 ASP A CB 1 ATOM 4677 C CG . ASP A 1 594 ? -3.513 -55.561 44.973 1.00 73.58 ? 621 ASP A CG 1 ATOM 4678 O OD1 . ASP A 1 594 ? -4.508 -55.008 45.486 1.00 69.30 ? 621 ASP A OD1 1 ATOM 4679 O OD2 . ASP A 1 594 ? -3.368 -55.690 43.737 1.00 70.48 1 621 ASP A OD2 1 ATOM 4680 N N . LYS A 1 603 ? 4.573 -55.860 48.665 1.00 42.32 ? 630 LYS A N 1 ATOM 4681 C CA . LYS A 1 603 ? 3.126 -55.947 48.827 1.00 55.61 ? 630 LYS A CA 1 ATOM 4682 C C . LYS A 1 603 ? 2.759 -56.109 50.302 1.00 62.15 ? 630 LYS A C 1 ATOM 4683 O O . LYS A 1 603 ? 3.637 -56.302 51.142 1.00 62.22 ? 630 LYS A O 1 ATOM 4684 C CB . LYS A 1 603 ? 2.552 -57.098 47.992 1.00 48.65 ? 630 LYS A CB 1 ATOM 4685 C CG . LYS A 1 603 ? 3.159 -58.460 48.289 1.00 52.18 ? 630 LYS A CG 1 ATOM 4686 C CD . LYS A 1 603 ? 2.090 -59.535 48.405 1.00 43.22 ? 630 LYS A CD 1 ATOM 4687 C CE . LYS A 1 603 ? 1.287 -59.671 47.125 1.00 41.44 ? 630 LYS A CE 1 ATOM 4688 N NZ . LYS A 1 603 ? 0.156 -60.631 47.288 1.00 34.86 1 630 LYS A NZ 1 ATOM 4689 N N . CYS A 1 604 ? 1.466 -56.030 50.609 1.00 65.56 ? 631 CYS A N 1 ATOM 4690 C CA . CYS A 1 604 ? 0.985 -56.085 51.993 1.00 62.98 ? 631 CYS A CA 1 ATOM 4691 C C . CYS A 1 604 ? 1.017 -57.488 52.605 1.00 65.25 ? 631 CYS A C 1 ATOM 4692 O O . CYS A 1 604 ? 0.764 -58.475 51.913 1.00 65.21 ? 631 CYS A O 1 ATOM 4693 C CB . CYS A 1 604 ? -0.429 -55.503 52.094 1.00 60.43 ? 631 CYS A CB 1 ATOM 4694 S SG . CYS A 1 604 ? -0.469 -53.749 52.527 1.00 81.52 ? 631 CYS A SG 1 ATOM 4695 N N . PRO A 1 605 ? 1.319 -57.572 53.915 1.00 68.22 ? 632 PRO A N 1 ATOM 4696 C CA . PRO A 1 605 ? 1.429 -58.834 54.664 1.00 68.48 ? 632 PRO A CA 1 ATOM 4697 C C . PRO A 1 605 ? 0.105 -59.580 54.815 1.00 66.40 ? 632 PRO A C 1 ATOM 4698 O O . PRO A 1 605 ? -0.961 -58.964 54.761 1.00 64.28 ? 632 PRO A O 1 ATOM 4699 C CB . PRO A 1 605 ? 1.925 -58.381 56.042 1.00 60.56 ? 632 PRO A CB 1 ATOM 4700 C CG . PRO A 1 605 ? 1.505 -56.961 56.150 1.00 56.46 ? 632 PRO A CG 1 ATOM 4701 C CD . PRO A 1 605 ? 1.629 -56.408 54.765 1.00 62.75 ? 632 PRO A CD 1 ATOM 4702 N N . ARG A 1 606 ? 0.184 -60.896 55.008 1.00 55.66 ? 633 ARG A N 1 ATOM 4703 C CA . ARG A 1 606 ? -1.008 -61.713 55.192 1.00 56.80 ? 633 ARG A CA 1 ATOM 4704 C C . ARG A 1 606 ? -1.678 -61.371 56.512 1.00 50.91 ? 633 ARG A C 1 ATOM 4705 O O . ARG A 1 606 ? -1.007 -61.104 57.503 1.00 58.85 ? 633 ARG A O 1 ATOM 4706 C CB . ARG A 1 606 ? -0.665 -63.205 55.149 1.00 71.95 ? 633 ARG A CB 1 ATOM 4707 C CG . ARG A 1 606 ? -0.248 -63.722 53.776 1.00 97.32 ? 633 ARG A CG 1 ATOM 4708 C CD . ARG A 1 606 ? -0.260 -65.249 53.731 1.00 107.48 ? 633 ARG A CD 1 ATOM 4709 N NE . ARG A 1 606 ? 0.342 -65.781 52.509 1.00 114.09 ? 633 ARG A NE 1 ATOM 4710 C CZ . ARG A 1 606 ? -0.326 -66.043 51.389 1.00 115.05 ? 633 ARG A CZ 1 ATOM 4711 N NH1 . ARG A 1 606 ? -1.633 -65.821 51.320 1.00 113.01 1 633 ARG A NH1 1 ATOM 4712 N NH2 . ARG A 1 606 ? 0.315 -66.527 50.333 1.00 110.94 ? 633 ARG A NH2 1 ATOM 4713 N N . GLY A 1 607 ? -3.006 -61.372 56.520 1.00 55.25 ? 634 GLY A N 1 ATOM 4714 C CA . GLY A 1 607 ? -3.759 -61.057 57.720 1.00 56.99 ? 634 GLY A CA 1 ATOM 4715 C C . GLY A 1 607 ? -3.926 -59.565 57.935 1.00 50.35 ? 634 GLY A C 1 ATOM 4716 O O . GLY A 1 607 ? -4.674 -59.135 58.817 1.00 43.31 ? 634 GLY A O 1 ATOM 4717 N N . CYS A 1 608 ? -3.231 -58.778 57.118 1.00 50.41 ? 635 CYS A N 1 ATOM 4718 C CA . CYS A 1 608 ? -3.249 -57.324 57.239 1.00 56.28 ? 635 CYS A CA 1 ATOM 4719 C C . CYS A 1 608 ? -3.864 -56.656 56.012 1.00 61.30 ? 635 CYS A C 1 ATOM 4720 O O . CYS A 1 608 ? -3.316 -56.744 54.911 1.00 63.96 ? 635 CYS A O 1 ATOM 4721 C CB . CYS A 1 608 ? -1.826 -56.784 57.425 1.00 58.92 ? 635 CYS A CB 1 ATOM 4722 S SG . CYS A 1 608 ? -0.869 -57.499 58.785 1.00 57.79 ? 635 CYS A SG 1 ATOM 4723 N N . ASN A 1 609 ? -4.993 -55.979 56.201 1.00 55.69 ? 636 ASN A N 1 ATOM 4724 C CA . ASN A 1 609 ? -5.554 -55.156 55.137 1.00 52.40 ? 636 ASN A CA 1 ATOM 4725 C C . ASN A 1 609 ? -4.812 -53.830 55.081 1.00 47.39 ? 636 ASN A C 1 ATOM 4726 O O . ASN A 1 609 ? -4.457 -53.261 56.111 1.00 51.07 ? 636 ASN A O 1 ATOM 4727 C CB . ASN A 1 609 ? -7.049 -54.919 55.346 1.00 56.79 ? 636 ASN A CB 1 ATOM 4728 C CG . ASN A 1 609 ? -7.339 -53.606 56.042 1.00 51.20 ? 636 ASN A CG 1 ATOM 4729 O OD1 . ASN A 1 609 ? -7.506 -52.568 55.395 1.00 54.36 ? 636 ASN A OD1 1 ATOM 4730 N ND2 . ASN A 1 609 ? -7.396 -53.641 57.368 1.00 43.37 ? 636 ASN A ND2 1 ATOM 4731 N N . CYS A 1 610 ? -4.558 -53.340 53.878 1.00 47.29 ? 637 CYS A N 1 ATOM 4732 C CA . CYS A 1 610 ? -3.759 -52.135 53.731 1.00 47.95 ? 637 CYS A CA 1 ATOM 4733 C C . CYS A 1 610 ? -4.393 -51.187 52.724 1.00 55.96 ? 637 CYS A C 1 ATOM 4734 O O . CYS A 1 610 ? -5.273 -51.582 51.957 1.00 56.03 ? 637 CYS A O 1 ATOM 4735 C CB . CYS A 1 610 ? -2.344 -52.509 53.303 1.00 46.09 ? 637 CYS A CB 1 ATOM 4736 S SG . CYS A 1 610 ? -1.763 -54.044 54.061 1.00 48.82 ? 637 CYS A SG 1 ATOM 4737 N N . HIS A 1 611 ? -3.948 -49.934 52.740 1.00 48.67 ? 638 HIS A N 1 ATOM 4738 C CA . HIS A 1 611 ? -4.458 -48.923 51.822 1.00 45.68 ? 638 HIS A CA 1 ATOM 4739 C C . HIS A 1 611 ? -3.582 -47.682 51.852 1.00 42.91 ? 638 HIS A C 1 ATOM 4740 O O . HIS A 1 611 ? -2.796 -47.494 52.775 1.00 41.95 ? 638 HIS A O 1 ATOM 4741 C CB . HIS A 1 611 ? -5.894 -48.542 52.178 1.00 44.11 ? 638 HIS A CB 1 ATOM 4742 C CG . HIS A 1 611 ? -6.033 -47.889 53.517 1.00 44.80 ? 638 HIS A CG 1 ATOM 4743 N ND1 . HIS A 1 611 ? -6.576 -48.534 54.606 1.00 47.79 ? 638 HIS A ND1 1 ATOM 4744 C CD2 . HIS A 1 611 ? -5.707 -46.644 53.940 1.00 41.17 ? 638 HIS A CD2 1 ATOM 4745 C CE1 . HIS A 1 611 ? -6.577 -47.716 55.644 1.00 48.82 ? 638 HIS A CE1 1 ATOM 4746 N NE2 . HIS A 1 611 ? -6.055 -46.563 55.267 1.00 45.24 ? 638 HIS A NE2 1 ATOM 4747 N N . VAL A 1 612 ? -3.733 -46.830 50.844 1.00 47.13 ? 639 VAL A N 1 ATOM 4748 C CA . VAL A 1 612 ? -2.964 -45.594 50.761 1.00 42.07 ? 639 VAL A CA 1 ATOM 4749 C C . VAL A 1 612 ? -3.856 -44.397 50.451 1.00 41.29 ? 639 VAL A C 1 ATOM 4750 O O . VAL A 1 612 ? -4.509 -44.360 49.410 1.00 39.30 ? 639 VAL A O 1 ATOM 4751 C CB . VAL A 1 612 ? -1.889 -45.680 49.670 1.00 28.37 ? 639 VAL A CB 1 ATOM 4752 C CG1 . VAL A 1 612 ? -1.200 -44.341 49.509 1.00 30.41 ? 639 VAL A CG1 1 ATOM 4753 C CG2 . VAL A 1 612 ? -0.892 -46.765 50.001 1.00 28.38 ? 639 VAL A CG2 1 ATOM 4754 N N . ARG A 1 613 ? -3.886 -43.422 51.354 1.00 39.51 ? 640 ARG A N 1 ATOM 4755 C CA . ARG A 1 613 ? -4.598 -42.178 51.093 1.00 39.09 ? 640 ARG A CA 1 ATOM 4756 C C . ARG A 1 613 ? -3.621 -41.126 50.606 1.00 35.64 ? 640 ARG A C 1 ATOM 4757 O O . ARG A 1 613 ? -2.610 -40.862 51.250 1.00 33.35 ? 640 ARG A O 1 ATOM 4758 C CB . ARG A 1 613 ? -5.331 -41.689 52.341 1.00 41.48 ? 640 ARG A CB 1 ATOM 4759 C CG . ARG A 1 613 ? -4.528 -41.816 53.611 1.00 41.25 ? 640 ARG A CG 1 ATOM 4760 C CD . ARG A 1 613 ? -5.429 -41.888 54.828 1.00 45.58 ? 640 ARG A CD 1 ATOM 4761 N NE . ARG A 1 613 ? -4.643 -42.095 56.038 1.00 53.36 ? 640 ARG A NE 1 ATOM 4762 C CZ . ARG A 1 613 ? -4.228 -41.115 56.832 1.00 45.72 ? 640 ARG A CZ 1 ATOM 4763 N NH1 . ARG A 1 613 ? -3.511 -41.392 57.912 1.00 36.23 1 640 ARG A NH1 1 ATOM 4764 N NH2 . ARG A 1 613 ? -4.541 -39.857 56.549 1.00 46.84 ? 640 ARG A NH2 1 ATOM 4765 N N . THR A 1 614 ? -3.923 -40.535 49.457 1.00 38.88 ? 641 THR A N 1 ATOM 4766 C CA . THR A 1 614 ? -3.049 -39.530 48.874 1.00 37.22 ? 641 THR A CA 1 ATOM 4767 C C . THR A 1 614 ? -3.334 -38.163 49.458 1.00 34.44 ? 641 THR A C 1 ATOM 4768 O O . THR A 1 614 ? -2.737 -37.174 49.049 1.00 37.60 ? 641 THR A O 1 ATOM 4769 C CB . THR A 1 614 ? -3.191 -39.454 47.345 1.00 40.17 ? 641 THR A CB 1 ATOM 4770 O OG1 . THR A 1 614 ? -4.574 -39.317 46.998 1.00 45.72 ? 641 THR A OG1 1 ATOM 4771 C CG2 . THR A 1 614 ? -2.626 -40.706 46.691 1.00 39.42 ? 641 THR A CG2 1 ATOM 4772 N N . TYR A 1 615 ? -4.250 -38.107 50.417 1.00 36.26 ? 642 TYR A N 1 ATOM 4773 C CA . TYR A 1 615 ? -4.521 -36.854 51.103 1.00 43.54 ? 642 TYR A CA 1 ATOM 4774 C C . TYR A 1 615 ? -3.310 -36.389 51.913 1.00 44.66 ? 642 TYR A C 1 ATOM 4775 O O . TYR A 1 615 ? -3.085 -35.189 52.078 1.00 41.96 ? 642 TYR A O 1 ATOM 4776 C CB . TYR A 1 615 ? -5.742 -36.979 52.011 1.00 43.87 ? 642 TYR A CB 1 ATOM 4777 C CG . TYR A 1 615 ? -5.873 -35.821 52.965 1.00 43.45 ? 642 TYR A CG 1 ATOM 4778 C CD1 . TYR A 1 615 ? -6.160 -34.544 52.498 1.00 42.88 ? 642 TYR A CD1 1 ATOM 4779 C CD2 . TYR A 1 615 ? -5.689 -35.997 54.328 1.00 46.53 ? 642 TYR A CD2 1 ATOM 4780 C CE1 . TYR A 1 615 ? -6.275 -33.475 53.364 1.00 56.89 ? 642 TYR A CE1 1 ATOM 4781 C CE2 . TYR A 1 615 ? -5.800 -34.934 55.206 1.00 64.66 ? 642 TYR A CE2 1 ATOM 4782 C CZ . TYR A 1 615 ? -6.094 -33.673 54.721 1.00 71.90 ? 642 TYR A CZ 1 ATOM 4783 O OH . TYR A 1 615 ? -6.205 -32.612 55.597 1.00 67.58 ? 642 TYR A OH 1 ATOM 4784 N N . ASP A 1 616 ? -2.531 -37.347 52.408 1.00 44.31 ? 643 ASP A N 1 ATOM 4785 C CA . ASP A 1 616 ? -1.366 -37.042 53.230 1.00 38.30 ? 643 ASP A CA 1 ATOM 4786 C C . ASP A 1 616 ? -0.169 -37.930 52.900 1.00 38.46 ? 643 ASP A C 1 ATOM 4787 O O . ASP A 1 616 ? 0.800 -37.972 53.657 1.00 44.19 ? 643 ASP A O 1 ATOM 4788 C CB . ASP A 1 616 ? -1.711 -37.179 54.714 1.00 41.20 ? 643 ASP A CB 1 ATOM 4789 C CG . ASP A 1 616 ? -2.367 -38.505 55.040 1.00 42.18 ? 643 ASP A CG 1 ATOM 4790 O OD1 . ASP A 1 616 ? -2.539 -39.329 54.119 1.00 43.93 ? 643 ASP A OD1 1 ATOM 4791 O OD2 . ASP A 1 616 ? -2.712 -38.729 56.219 1.00 39.74 1 643 ASP A OD2 1 ATOM 4792 N N . LYS A 1 617 ? -0.248 -38.633 51.773 1.00 38.80 ? 644 LYS A N 1 ATOM 4793 C CA . LYS A 1 617 ? 0.804 -39.552 51.333 1.00 41.17 ? 644 LYS A CA 1 ATOM 4794 C C . LYS A 1 617 ? 1.131 -40.585 52.403 1.00 40.61 ? 644 LYS A C 1 ATOM 4795 O O . LYS A 1 617 ? 2.292 -40.932 52.607 1.00 42.50 ? 644 LYS A O 1 ATOM 4796 C CB . LYS A 1 617 ? 2.068 -38.785 50.945 1.00 39.85 ? 644 LYS A CB 1 ATOM 4797 C CG . LYS A 1 617 ? 1.812 -37.578 50.060 1.00 44.27 ? 644 LYS A CG 1 ATOM 4798 C CD . LYS A 1 617 ? 3.115 -36.882 49.691 1.00 56.86 ? 644 LYS A CD 1 ATOM 4799 C CE . LYS A 1 617 ? 2.868 -35.520 49.055 1.00 53.41 ? 644 LYS A CE 1 ATOM 4800 N NZ . LYS A 1 617 ? 4.144 -34.826 48.712 1.00 49.13 1 644 LYS A NZ 1 ATOM 4801 N N . ALA A 1 618 ? 0.099 -41.077 53.078 1.00 39.18 ? 645 ALA A N 1 ATOM 4802 C CA . ALA A 1 618 ? 0.279 -41.950 54.232 1.00 39.75 ? 645 ALA A CA 1 ATOM 4803 C C . ALA A 1 618 ? 0.021 -43.416 53.916 1.00 43.71 ? 645 ALA A C 1 ATOM 4804 O O . ALA A 1 618 ? -1.101 -43.797 53.577 1.00 47.31 ? 645 ALA A O 1 ATOM 4805 C CB . ALA A 1 618 ? -0.622 -41.499 55.372 1.00 46.15 ? 645 ALA A CB 1 ATOM 4806 N N . LEU A 1 619 ? 1.057 -44.239 54.044 1.00 37.86 ? 646 LEU A N 1 ATOM 4807 C CA . LEU A 1 619 ? 0.906 -45.677 53.862 1.00 35.52 ? 646 LEU A CA 1 ATOM 4808 C C . LEU A 1 619 ? 0.436 -46.321 55.161 1.00 33.08 ? 646 LEU A C 1 ATOM 4809 O O . LEU A 1 619 ? 1.182 -46.399 56.136 1.00 37.17 ? 646 LEU A O 1 ATOM 4810 C CB . LEU A 1 619 ? 2.212 -46.304 53.372 1.00 31.72 ? 646 LEU A CB 1 ATOM 4811 C CG . LEU A 1 619 ? 2.289 -47.829 53.295 1.00 28.50 ? 646 LEU A CG 1 ATOM 4812 C CD1 . LEU A 1 619 ? 1.070 -48.432 52.616 1.00 26.23 ? 646 LEU A CD1 1 ATOM 4813 C CD2 . LEU A 1 619 ? 3.559 -48.230 52.568 1.00 32.65 ? 646 LEU A CD2 1 ATOM 4814 N N . VAL A 1 620 ? -0.812 -46.775 55.160 1.00 32.61 ? 647 VAL A N 1 ATOM 4815 C CA . VAL A 1 620 ? -1.438 -47.349 56.343 1.00 30.84 ? 647 VAL A CA 1 ATOM 4816 C C . VAL A 1 620 ? -1.438 -48.874 56.278 1.00 38.21 ? 647 VAL A C 1 ATOM 4817 O O . VAL A 1 620 ? -1.707 -49.456 55.227 1.00 51.69 ? 647 VAL A O 1 ATOM 4818 C CB . VAL A 1 620 ? -2.881 -46.846 56.488 1.00 27.94 ? 647 VAL A CB 1 ATOM 4819 C CG1 . VAL A 1 620 ? -3.517 -47.401 57.749 1.00 29.18 ? 647 VAL A CG1 1 ATOM 4820 C CG2 . VAL A 1 620 ? -2.904 -45.326 56.491 1.00 30.16 ? 647 VAL A CG2 1 ATOM 4821 N N . ILE A 1 621 ? -1.123 -49.519 57.398 1.00 33.62 ? 648 ILE A N 1 ATOM 4822 C CA . ILE A 1 621 ? -1.076 -50.973 57.454 1.00 28.77 ? 648 ILE A CA 1 ATOM 4823 C C . ILE A 1 621 ? -1.822 -51.499 58.670 1.00 29.84 ? 648 ILE A C 1 ATOM 4824 O O . ILE A 1 621 ? -1.312 -51.436 59.782 1.00 37.59 ? 648 ILE A O 1 ATOM 4825 C CB . ILE A 1 621 ? 0.365 -51.473 57.539 1.00 25.41 ? 648 ILE A CB 1 ATOM 4826 C CG1 . ILE A 1 621 ? 1.251 -50.727 56.539 1.00 27.17 ? 648 ILE A CG1 1 ATOM 4827 C CG2 . ILE A 1 621 ? 0.409 -52.970 57.314 1.00 35.59 ? 648 ILE A CG2 1 ATOM 4828 C CD1 . ILE A 1 621 ? 2.699 -51.157 56.563 1.00 32.76 ? 648 ILE A CD1 1 ATOM 4829 N N . ASN A 1 622 ? -3.024 -52.026 58.462 1.00 36.06 ? 649 ASN A N 1 ATOM 4830 C CA . ASN A 1 622 ? -3.845 -52.510 59.571 1.00 39.83 ? 649 ASN A CA 1 ATOM 4831 C C . ASN A 1 622 ? -3.751 -54.017 59.798 1.00 47.49 ? 649 ASN A C 1 ATOM 4832 O O . ASN A 1 622 ? -4.347 -54.804 59.061 1.00 50.73 ? 649 ASN A O 1 ATOM 4833 C CB . ASN A 1 622 ? -5.305 -52.109 59.373 1.00 35.63 ? 649 ASN A CB 1 ATOM 4834 C CG . ASN A 1 622 ? -5.484 -50.615 59.270 1.00 39.99 ? 649 ASN A CG 1 ATOM 4835 O OD1 . ASN A 1 622 ? -4.646 -49.849 59.741 1.00 40.51 ? 649 ASN A OD1 1 ATOM 4836 N ND2 . ASN A 1 622 ? -6.579 -50.189 58.652 1.00 44.52 ? 649 ASN A ND2 1 ATOM 4837 N N . CYS A 1 623 ? -3.009 -54.410 60.828 1.00 49.66 ? 650 CYS A N 1 ATOM 4838 C CA . CYS A 1 623 ? -2.862 -55.818 61.178 1.00 47.24 ? 650 CYS A CA 1 ATOM 4839 C C . CYS A 1 623 ? -3.591 -56.120 62.478 1.00 46.64 ? 650 CYS A C 1 ATOM 4840 O O . CYS A 1 623 ? -2.984 -56.559 63.451 1.00 46.01 ? 650 CYS A O 1 ATOM 4841 C CB . CYS A 1 623 ? -1.385 -56.184 61.316 1.00 45.42 ? 650 CYS A CB 1 ATOM 4842 S SG . CYS A 1 623 ? -0.392 -55.834 59.847 1.00 53.28 ? 650 CYS A SG 1 ATOM 4843 N N . HIS A 1 624 ? -4.900 -55.890 62.481 1.00 50.49 ? 651 HIS A N 1 ATOM 4844 C CA . HIS A 1 624 ? -5.708 -56.022 63.688 1.00 53.13 ? 651 HIS A CA 1 ATOM 4845 C C . HIS A 1 624 ? -6.359 -57.395 63.777 1.00 62.35 ? 651 HIS A C 1 ATOM 4846 O O . HIS A 1 624 ? -7.539 -57.522 64.107 1.00 57.97 ? 651 HIS A O 1 ATOM 4847 C CB . HIS A 1 624 ? -6.767 -54.927 63.723 1.00 46.65 ? 651 HIS A CB 1 ATOM 4848 C CG . HIS A 1 624 ? -6.232 -53.574 63.379 1.00 48.07 ? 651 HIS A CG 1 ATOM 4849 N ND1 . HIS A 1 624 ? -6.994 -52.607 62.760 1.00 53.35 ? 651 HIS A ND1 1 ATOM 4850 C CD2 . HIS A 1 624 ? -5.006 -53.030 63.559 1.00 46.64 ? 651 HIS A CD2 1 ATOM 4851 C CE1 . HIS A 1 624 ? -6.261 -51.523 62.579 1.00 53.38 ? 651 HIS A CE1 1 ATOM 4852 N NE2 . HIS A 1 624 ? -5.050 -51.754 63.053 1.00 48.26 ? 651 HIS A NE2 1 ATOM 4853 N N . SER A 1 625 ? -5.570 -58.421 63.479 1.00 70.54 ? 652 SER A N 1 ATOM 4854 C CA . SER A 1 625 ? -6.024 -59.801 63.563 1.00 69.91 ? 652 SER A CA 1 ATOM 4855 C C . SER A 1 625 ? -6.011 -60.278 65.013 1.00 68.66 ? 652 SER A C 1 ATOM 4856 O O . SER A 1 625 ? -6.937 -60.953 65.463 1.00 65.10 ? 652 SER A O 1 ATOM 4857 C CB . SER A 1 625 ? -5.133 -60.690 62.696 1.00 66.74 ? 652 SER A CB 1 ATOM 4858 O OG . SER A 1 625 ? -3.779 -60.278 62.780 1.00 56.83 ? 652 SER A OG 1 ATOM 4859 N N . GLY A 1 626 ? -4.956 -59.917 65.738 1.00 64.56 ? 653 GLY A N 1 ATOM 4860 C CA . GLY A 1 626 ? -4.843 -60.254 67.145 1.00 63.13 ? 653 GLY A CA 1 ATOM 4861 C C . GLY A 1 626 ? -4.020 -61.501 67.406 1.00 66.05 ? 653 GLY A C 1 ATOM 4862 O O . GLY A 1 626 ? -4.213 -62.177 68.419 1.00 62.91 ? 653 GLY A O 1 ATOM 4863 N N . ASN A 1 627 ? -3.092 -61.805 66.503 1.00 63.05 ? 654 ASN A N 1 ATOM 4864 C CA . ASN A 1 627 ? -2.344 -63.054 66.607 1.00 62.33 ? 654 ASN A CA 1 ATOM 4865 C C . ASN A 1 627 ? -0.870 -62.990 66.167 1.00 64.85 ? 654 ASN A C 1 ATOM 4866 O O . ASN A 1 627 ? -0.301 -63.982 65.712 1.00 69.08 ? 654 ASN A O 1 ATOM 4867 C CB . ASN A 1 627 ? -3.116 -64.193 65.907 1.00 63.42 ? 654 ASN A CB 1 ATOM 4868 C CG . ASN A 1 627 ? -2.847 -64.279 64.398 1.00 66.98 ? 654 ASN A CG 1 ATOM 4869 O OD1 . ASN A 1 627 ? -2.010 -65.071 63.968 1.00 74.90 ? 654 ASN A OD1 1 ATOM 4870 N ND2 . ASN A 1 627 ? -3.579 -63.499 63.596 1.00 64.29 ? 654 ASN A ND2 1 ATOM 4871 N N . LEU A 1 628 ? -0.240 -61.832 66.340 1.00 58.03 ? 655 LEU A N 1 ATOM 4872 C CA . LEU A 1 628 ? 1.146 -61.651 65.907 1.00 54.68 ? 655 LEU A CA 1 ATOM 4873 C C . LEU A 1 628 ? 2.096 -61.448 67.083 1.00 54.09 ? 655 LEU A C 1 ATOM 4874 O O . LEU A 1 628 ? 1.819 -60.648 67.967 1.00 56.87 ? 655 LEU A O 1 ATOM 4875 C CB . LEU A 1 628 ? 1.255 -60.454 64.959 1.00 55.74 ? 655 LEU A CB 1 ATOM 4876 C CG . LEU A 1 628 ? 0.784 -60.597 63.510 1.00 51.52 ? 655 LEU A CG 1 ATOM 4877 C CD1 . LEU A 1 628 ? -0.704 -60.866 63.411 1.00 60.43 ? 655 LEU A CD1 1 ATOM 4878 C CD2 . LEU A 1 628 ? 1.128 -59.341 62.747 1.00 51.25 ? 655 LEU A CD2 1 ATOM 4879 N N . THR A 1 629 ? 3.216 -62.168 67.088 1.00 57.59 ? 656 THR A N 1 ATOM 4880 C CA . THR A 1 629 ? 4.233 -61.991 68.124 1.00 57.50 ? 656 THR A CA 1 ATOM 4881 C C . THR A 1 629 ? 5.398 -61.180 67.569 1.00 56.44 ? 656 THR A C 1 ATOM 4882 O O . THR A 1 629 ? 6.098 -60.477 68.301 1.00 52.43 ? 656 THR A O 1 ATOM 4883 C CB . THR A 1 629 ? 4.768 -63.338 68.647 1.00 57.65 ? 656 THR A CB 1 ATOM 4884 O OG1 . THR A 1 629 ? 5.648 -63.917 67.675 1.00 66.44 ? 656 THR A OG1 1 ATOM 4885 C CG2 . THR A 1 629 ? 3.617 -64.295 68.938 1.00 48.24 ? 656 THR A CG2 1 ATOM 4886 N N . HIS A 1 630 ? 5.600 -61.292 66.263 1.00 54.52 ? 657 HIS A N 1 ATOM 4887 C CA . HIS A 1 630 ? 6.603 -60.498 65.578 1.00 58.60 ? 657 HIS A CA 1 ATOM 4888 C C . HIS A 1 630 ? 5.931 -59.463 64.692 1.00 63.28 ? 657 HIS A C 1 ATOM 4889 O O . HIS A 1 630 ? 4.760 -59.605 64.330 1.00 51.63 ? 657 HIS A O 1 ATOM 4890 C CB . HIS A 1 630 ? 7.503 -61.395 64.733 1.00 60.97 ? 657 HIS A CB 1 ATOM 4891 C CG . HIS A 1 630 ? 8.466 -62.208 65.539 1.00 77.99 ? 657 HIS A CG 1 ATOM 4892 N ND1 . HIS A 1 630 ? 9.461 -62.969 64.965 1.00 83.68 ? 657 HIS A ND1 1 ATOM 4893 C CD2 . HIS A 1 630 ? 8.590 -62.372 66.878 1.00 75.82 ? 657 HIS A CD2 1 ATOM 4894 C CE1 . HIS A 1 630 ? 10.156 -63.570 65.916 1.00 87.20 ? 657 HIS A CE1 1 ATOM 4895 N NE2 . HIS A 1 630 ? 9.647 -63.224 67.085 1.00 80.75 ? 657 HIS A NE2 1 ATOM 4896 N N . VAL A 1 631 ? 6.672 -58.413 64.357 1.00 63.34 ? 658 VAL A N 1 ATOM 4897 C CA . VAL A 1 631 ? 6.199 -57.458 63.369 1.00 58.04 ? 658 VAL A CA 1 ATOM 4898 C C . VAL A 1 631 ? 6.434 -58.065 61.995 1.00 60.31 ? 658 VAL A C 1 ATOM 4899 O O . VAL A 1 631 ? 7.578 -58.344 61.625 1.00 52.44 ? 658 VAL A O 1 ATOM 4900 C CB . VAL A 1 631 ? 6.922 -56.107 63.473 1.00 51.78 ? 658 VAL A CB 1 ATOM 4901 C CG1 . VAL A 1 631 ? 6.459 -55.178 62.368 1.00 49.86 ? 658 VAL A CG1 1 ATOM 4902 C CG2 . VAL A 1 631 ? 6.663 -55.478 64.825 1.00 58.38 ? 658 VAL A CG2 1 ATOM 4903 N N . PRO A 1 632 ? 5.344 -58.281 61.240 1.00 58.49 ? 659 PRO A N 1 ATOM 4904 C CA . PRO A 1 632 ? 5.361 -58.944 59.933 1.00 52.39 ? 659 PRO A CA 1 ATOM 4905 C C . PRO A 1 632 ? 6.177 -58.149 58.926 1.00 56.05 ? 659 PRO A C 1 ATOM 4906 O O . PRO A 1 632 ? 6.394 -56.955 59.130 1.00 57.22 ? 659 PRO A O 1 ATOM 4907 C CB . PRO A 1 632 ? 3.885 -58.950 59.531 1.00 48.61 ? 659 PRO A CB 1 ATOM 4908 C CG . PRO A 1 632 ? 3.302 -57.790 60.247 1.00 47.71 ? 659 PRO A CG 1 ATOM 4909 C CD . PRO A 1 632 ? 4.009 -57.751 61.566 1.00 51.85 ? 659 PRO A CD 1 ATOM 4910 N N . ARG A 1 633 ? 6.629 -58.804 57.860 1.00 59.73 ? 660 ARG A N 1 ATOM 4911 C CA . ARG A 1 633 ? 7.461 -58.143 56.858 1.00 70.60 ? 660 ARG A CA 1 ATOM 4912 C C . ARG A 1 633 ? 6.716 -56.991 56.187 1.00 65.76 ? 660 ARG A C 1 ATOM 4913 O O . ARG A 1 633 ? 5.638 -57.176 55.613 1.00 52.50 ? 660 ARG A O 1 ATOM 4914 C CB . ARG A 1 633 ? 7.956 -59.144 55.812 1.00 80.70 ? 660 ARG A CB 1 ATOM 4915 C CG . ARG A 1 633 ? 8.845 -60.243 56.371 1.00 85.57 ? 660 ARG A CG 1 ATOM 4916 C CD . ARG A 1 633 ? 9.324 -61.181 55.268 1.00 94.25 ? 660 ARG A CD 1 ATOM 4917 N NE . ARG A 1 633 ? 10.092 -62.306 55.796 1.00 92.71 ? 660 ARG A NE 1 ATOM 4918 C CZ . ARG A 1 633 ? 10.622 -63.268 55.048 1.00 91.33 ? 660 ARG A CZ 1 ATOM 4919 N NH1 . ARG A 1 633 ? 10.469 -63.247 53.730 1.00 94.96 1 660 ARG A NH1 1 ATOM 4920 N NH2 . ARG A 1 633 ? 11.305 -64.253 55.616 1.00 96.12 ? 660 ARG A NH2 1 ATOM 4921 N N . LEU A 1 634 ? 7.304 -55.802 56.263 1.00 62.84 ? 661 LEU A N 1 ATOM 4922 C CA . LEU A 1 634 ? 6.648 -54.598 55.773 1.00 59.31 ? 661 LEU A CA 1 ATOM 4923 C C . LEU A 1 634 ? 7.172 -54.142 54.413 1.00 50.25 ? 661 LEU A C 1 ATOM 4924 O O . LEU A 1 634 ? 8.384 -54.083 54.196 1.00 46.96 ? 661 LEU A O 1 ATOM 4925 C CB . LEU A 1 634 ? 6.775 -53.469 56.800 1.00 54.00 ? 661 LEU A CB 1 ATOM 4926 C CG . LEU A 1 634 ? 6.069 -53.694 58.141 1.00 48.45 ? 661 LEU A CG 1 ATOM 4927 C CD1 . LEU A 1 634 ? 6.181 -52.451 59.003 1.00 49.67 ? 661 LEU A CD1 1 ATOM 4928 C CD2 . LEU A 1 634 ? 4.608 -54.085 57.949 1.00 41.67 ? 661 LEU A CD2 1 ATOM 4929 N N . PRO A 1 635 ? 6.247 -53.819 53.493 1.00 42.82 ? 662 PRO A N 1 ATOM 4930 C CA . PRO A 1 635 ? 6.586 -53.293 52.168 1.00 46.07 ? 662 PRO A CA 1 ATOM 4931 C C . PRO A 1 635 ? 7.243 -51.926 52.287 1.00 47.84 ? 662 PRO A C 1 ATOM 4932 O O . PRO A 1 635 ? 6.805 -51.115 53.100 1.00 53.56 ? 662 PRO A O 1 ATOM 4933 C CB . PRO A 1 635 ? 5.220 -53.167 51.485 1.00 50.04 ? 662 PRO A CB 1 ATOM 4934 C CG . PRO A 1 635 ? 4.244 -53.050 52.602 1.00 44.48 ? 662 PRO A CG 1 ATOM 4935 C CD . PRO A 1 635 ? 4.790 -53.914 53.691 1.00 45.02 ? 662 PRO A CD 1 ATOM 4936 N N . ASN A 1 636 ? 8.277 -51.676 51.490 1.00 45.31 ? 663 ASN A N 1 ATOM 4937 C CA . ASN A 1 636 ? 9.021 -50.424 51.567 1.00 49.80 ? 663 ASN A CA 1 ATOM 4938 C C . ASN A 1 636 ? 8.162 -49.196 51.262 1.00 60.72 ? 663 ASN A C 1 ATOM 4939 O O . ASN A 1 636 ? 7.104 -49.301 50.638 1.00 59.86 ? 663 ASN A O 1 ATOM 4940 C CB . ASN A 1 636 ? 10.226 -50.465 50.626 1.00 53.67 ? 663 ASN A CB 1 ATOM 4941 C CG . ASN A 1 636 ? 11.493 -49.942 51.276 1.00 65.33 ? 663 ASN A CG 1 ATOM 4942 O OD1 . ASN A 1 636 ? 11.607 -48.752 51.582 1.00 63.54 ? 663 ASN A OD1 1 ATOM 4943 N ND2 . ASN A 1 636 ? 12.460 -50.832 51.481 1.00 64.02 ? 663 ASN A ND2 1 ATOM 4944 N N . LEU A 1 637 ? 8.623 -48.031 51.709 1.00 65.52 ? 664 LEU A N 1 ATOM 4945 C CA . LEU A 1 637 ? 7.918 -46.778 51.460 1.00 72.12 ? 664 LEU A CA 1 ATOM 4946 C C . LEU A 1 637 ? 8.484 -46.096 50.216 1.00 75.71 ? 664 LEU A C 1 ATOM 4947 O O . LEU A 1 637 ? 9.700 -45.940 50.085 1.00 71.03 ? 664 LEU A O 1 ATOM 4948 C CB . LEU A 1 637 ? 8.020 -45.852 52.681 1.00 67.01 ? 664 LEU A CB 1 ATOM 4949 C CG . LEU A 1 637 ? 7.284 -44.506 52.656 1.00 56.50 ? 664 LEU A CG 1 ATOM 4950 C CD1 . LEU A 1 637 ? 6.328 -44.370 53.832 1.00 37.56 ? 664 LEU A CD1 1 ATOM 4951 C CD2 . LEU A 1 637 ? 8.268 -43.346 52.637 1.00 52.15 ? 664 LEU A CD2 1 ATOM 4952 N N . HIS A 1 638 ? 7.596 -45.707 49.303 1.00 71.95 ? 665 HIS A N 1 ATOM 4953 C CA . HIS A 1 638 ? 7.990 -45.015 48.079 1.00 79.36 ? 665 HIS A CA 1 ATOM 4954 C C . HIS A 1 638 ? 8.725 -43.719 48.419 1.00 83.71 ? 665 HIS A C 1 ATOM 4955 O O . HIS A 1 638 ? 8.440 -43.091 49.439 1.00 87.97 ? 665 HIS A O 1 ATOM 4956 C CB . HIS A 1 638 ? 6.751 -44.708 47.231 1.00 77.66 ? 665 HIS A CB 1 ATOM 4957 C CG . HIS A 1 638 ? 7.057 -44.327 45.813 1.00 85.25 ? 665 HIS A CG 1 ATOM 4958 N ND1 . HIS A 1 638 ? 7.670 -43.140 45.473 1.00 85.40 ? 665 HIS A ND1 1 ATOM 4959 C CD2 . HIS A 1 638 ? 6.816 -44.970 44.646 1.00 82.11 ? 665 HIS A CD2 1 ATOM 4960 C CE1 . HIS A 1 638 ? 7.804 -43.072 44.161 1.00 80.58 ? 665 HIS A CE1 1 ATOM 4961 N NE2 . HIS A 1 638 ? 7.294 -44.172 43.635 1.00 81.19 ? 665 HIS A NE2 1 ATOM 4962 N N . LYS A 1 639 ? 9.664 -43.315 47.564 1.00 81.59 ? 666 LYS A N 1 ATOM 4963 C CA . LYS A 1 639 ? 10.390 -42.057 47.751 1.00 82.78 ? 666 LYS A CA 1 ATOM 4964 C C . LYS A 1 639 ? 9.506 -40.835 47.472 1.00 81.36 ? 666 LYS A C 1 ATOM 4965 O O . LYS A 1 639 ? 9.998 -39.711 47.367 1.00 75.35 ? 666 LYS A O 1 ATOM 4966 C CB . LYS A 1 639 ? 11.643 -42.015 46.870 1.00 83.61 ? 666 LYS A CB 1 ATOM 4967 C CG . LYS A 1 639 ? 12.966 -41.930 47.637 1.00 96.54 ? 666 LYS A CG 1 ATOM 4968 C CD . LYS A 1 639 ? 13.267 -43.210 48.411 1.00 90.00 ? 666 LYS A CD 1 ATOM 4969 C CE . LYS A 1 639 ? 14.725 -43.268 48.862 1.00 77.60 ? 666 LYS A CE 1 ATOM 4970 N NZ . LYS A 1 639 ? 15.102 -42.136 49.758 1.00 71.45 1 666 LYS A NZ 1 ATOM 4971 N N . ASN A 1 640 ? 8.203 -41.075 47.345 1.00 76.48 ? 667 ASN A N 1 ATOM 4972 C CA . ASN A 1 640 ? 7.204 -40.025 47.202 1.00 70.14 ? 667 ASN A CA 1 ATOM 4973 C C . ASN A 1 640 ? 6.375 -39.914 48.474 1.00 74.64 ? 667 ASN A C 1 ATOM 4974 O O . ASN A 1 640 ? 5.921 -38.830 48.840 1.00 75.03 ? 667 ASN A O 1 ATOM 4975 C CB . ASN A 1 640 ? 6.289 -40.321 46.012 1.00 77.39 ? 667 ASN A CB 1 ATOM 4976 C CG . ASN A 1 640 ? 5.028 -39.471 46.012 1.00 84.15 ? 667 ASN A CG 1 ATOM 4977 O OD1 . ASN A 1 640 ? 4.018 -39.831 46.622 1.00 72.39 ? 667 ASN A OD1 1 ATOM 4978 N ND2 . ASN A 1 640 ? 5.078 -38.340 45.317 1.00 89.67 ? 667 ASN A ND2 1 ATOM 4979 N N . MET A 1 641 ? 6.184 -41.046 49.145 1.00 72.04 ? 668 MET A N 1 ATOM 4980 C CA . MET A 1 641 ? 5.375 -41.100 50.358 1.00 58.69 ? 668 MET A CA 1 ATOM 4981 C C . MET A 1 641 ? 6.076 -40.406 51.526 1.00 53.00 ? 668 MET A C 1 ATOM 4982 O O . MET A 1 641 ? 7.288 -40.190 51.493 1.00 49.30 ? 668 MET A O 1 ATOM 4983 C CB . MET A 1 641 ? 5.054 -42.552 50.714 1.00 61.90 ? 668 MET A CB 1 ATOM 4984 C CG . MET A 1 641 ? 4.448 -43.363 49.573 1.00 67.93 ? 668 MET A CG 1 ATOM 4985 S SD . MET A 1 641 ? 2.686 -43.065 49.307 1.00 66.13 ? 668 MET A SD 1 ATOM 4986 C CE . MET A 1 641 ? 2.033 -43.581 50.890 1.00 47.39 ? 668 MET A CE 1 ATOM 4987 N N . GLN A 1 642 ? 5.306 -40.060 52.554 1.00 51.98 ? 669 GLN A N 1 ATOM 4988 C CA . GLN A 1 642 ? 5.831 -39.307 53.691 1.00 50.21 ? 669 GLN A CA 1 ATOM 4989 C C . GLN A 1 642 ? 5.415 -39.882 55.040 1.00 35.11 ? 669 GLN A C 1 ATOM 4990 O O . GLN A 1 642 ? 6.052 -39.624 56.056 1.00 39.29 ? 669 GLN A O 1 ATOM 4991 C CB . GLN A 1 642 ? 5.377 -37.850 53.615 1.00 47.37 ? 669 GLN A CB 1 ATOM 4992 C CG . GLN A 1 642 ? 5.946 -37.071 52.450 1.00 41.87 ? 669 GLN A CG 1 ATOM 4993 C CD . GLN A 1 642 ? 5.257 -35.737 52.280 1.00 46.08 ? 669 GLN A CD 1 ATOM 4994 O OE1 . GLN A 1 642 ? 4.258 -35.452 52.947 1.00 36.86 ? 669 GLN A OE1 1 ATOM 4995 N NE2 . GLN A 1 642 ? 5.782 -34.908 51.384 1.00 46.43 ? 669 GLN A NE2 1 ATOM 4996 N N . LEU A 1 643 ? 4.331 -40.640 55.054 1.00 31.20 ? 670 LEU A N 1 ATOM 4997 C CA . LEU A 1 643 ? 3.829 -41.206 56.293 1.00 33.89 ? 670 LEU A CA 1 ATOM 4998 C C . LEU A 1 643 ? 3.651 -42.710 56.152 1.00 39.02 ? 670 LEU A C 1 ATOM 4999 O O . LEU A 1 643 ? 3.184 -43.194 55.124 1.00 44.42 ? 670 LEU A O 1 ATOM 5000 C CB . LEU A 1 643 ? 2.494 -40.563 56.673 1.00 34.22 ? 670 LEU A CB 1 ATOM 5001 C CG . LEU A 1 643 ? 2.438 -39.334 57.582 1.00 31.16 ? 670 LEU A CG 1 ATOM 5002 C CD1 . LEU A 1 643 ? 3.226 -38.177 57.005 1.00 28.10 ? 670 LEU A CD1 1 ATOM 5003 C CD2 . LEU A 1 643 ? 0.988 -38.939 57.810 1.00 29.09 ? 670 LEU A CD2 1 ATOM 5004 N N . MET A 1 644 ? 4.022 -43.446 57.191 1.00 35.71 ? 671 MET A N 1 ATOM 5005 C CA . MET A 1 644 ? 3.835 -44.887 57.203 1.00 30.59 ? 671 MET A CA 1 ATOM 5006 C C . MET A 1 644 ? 3.254 -45.295 58.542 1.00 29.20 ? 671 MET A C 1 ATOM 5007 O O . MET A 1 644 ? 3.937 -45.214 59.556 1.00 42.89 ? 671 MET A O 1 ATOM 5008 C CB . MET A 1 644 ? 5.170 -45.589 56.978 1.00 30.82 ? 671 MET A CB 1 ATOM 5009 C CG . MET A 1 644 ? 5.062 -47.093 56.860 1.00 30.11 ? 671 MET A CG 1 ATOM 5010 S SD . MET A 1 644 ? 6.550 -47.834 56.164 1.00 27.57 ? 671 MET A SD 1 ATOM 5011 C CE . MET A 1 644 ? 6.042 -49.547 56.065 1.00 28.70 ? 671 MET A CE 1 ATOM 5012 N N . GLU A 1 645 ? 1.999 -45.728 58.555 1.00 21.96 ? 672 GLU A N 1 ATOM 5013 C CA . GLU A 1 645 ? 1.323 -45.999 59.821 1.00 25.12 ? 672 GLU A CA 1 ATOM 5014 C C . GLU A 1 645 ? 1.184 -47.477 60.155 1.00 26.99 ? 672 GLU A C 1 ATOM 5015 O O . GLU A 1 645 ? 0.164 -48.093 59.858 1.00 27.60 ? 672 GLU A O 1 ATOM 5016 C CB . GLU A 1 645 ? -0.059 -45.351 59.845 1.00 28.38 ? 672 GLU A CB 1 ATOM 5017 C CG . GLU A 1 645 ? -0.048 -43.841 59.764 1.00 28.57 ? 672 GLU A CG 1 ATOM 5018 C CD . GLU A 1 645 ? -1.448 -43.269 59.735 1.00 30.58 ? 672 GLU A CD 1 ATOM 5019 O OE1 . GLU A 1 645 ? -1.598 -42.092 59.343 1.00 38.12 ? 672 GLU A OE1 1 ATOM 5020 O OE2 . GLU A 1 645 ? -2.397 -43.999 60.100 1.00 21.62 1 672 GLU A OE2 1 ATOM 5021 N N . LEU A 1 646 ? 2.200 -48.035 60.803 1.00 30.93 ? 673 LEU A N 1 ATOM 5022 C CA . LEU A 1 646 ? 2.156 -49.424 61.242 1.00 31.15 ? 673 LEU A CA 1 ATOM 5023 C C . LEU A 1 646 ? 1.162 -49.614 62.390 1.00 31.74 ? 673 LEU A C 1 ATOM 5024 O O . LEU A 1 646 ? 1.486 -49.380 63.552 1.00 34.03 ? 673 LEU A O 1 ATOM 5025 C CB . LEU A 1 646 ? 3.550 -49.899 61.654 1.00 28.21 ? 673 LEU A CB 1 ATOM 5026 C CG . LEU A 1 646 ? 3.647 -51.367 62.065 1.00 32.37 ? 673 LEU A CG 1 ATOM 5027 C CD1 . LEU A 1 646 ? 3.105 -52.260 60.969 1.00 36.05 ? 673 LEU A CD1 1 ATOM 5028 C CD2 . LEU A 1 646 ? 5.079 -51.739 62.397 1.00 35.77 ? 673 LEU A CD2 1 ATOM 5029 N N . HIS A 1 647 ? -0.053 -50.031 62.054 1.00 31.45 ? 674 HIS A N 1 ATOM 5030 C CA . HIS A 1 647 ? -1.097 -50.236 63.049 1.00 31.97 ? 674 HIS A CA 1 ATOM 5031 C C . HIS A 1 647 ? -1.146 -51.688 63.498 1.00 36.02 ? 674 HIS A C 1 ATOM 5032 O O . HIS A 1 647 ? -1.671 -52.545 62.789 1.00 36.71 ? 674 HIS A O 1 ATOM 5033 C CB . HIS A 1 647 ? -2.458 -49.823 62.487 1.00 34.69 ? 674 HIS A CB 1 ATOM 5034 C CG . HIS A 1 647 ? -2.696 -48.345 62.496 1.00 35.60 ? 674 HIS A CG 1 ATOM 5035 N ND1 . HIS A 1 647 ? -3.575 -47.739 63.370 1.00 31.18 ? 674 HIS A ND1 1 ATOM 5036 C CD2 . HIS A 1 647 ? -2.174 -47.353 61.736 1.00 28.26 ? 674 HIS A CD2 1 ATOM 5037 C CE1 . HIS A 1 647 ? -3.580 -46.436 63.150 1.00 29.30 ? 674 HIS A CE1 1 ATOM 5038 N NE2 . HIS A 1 647 ? -2.741 -46.177 62.163 1.00 28.65 ? 674 HIS A NE2 1 ATOM 5039 N N . LEU A 1 648 ? -0.606 -51.956 64.685 1.00 41.96 ? 675 LEU A N 1 ATOM 5040 C CA . LEU A 1 648 ? -0.555 -53.314 65.227 1.00 42.06 ? 675 LEU A CA 1 ATOM 5041 C C . LEU A 1 648 ? -1.376 -53.457 66.509 1.00 35.21 ? 675 LEU A C 1 ATOM 5042 O O . LEU A 1 648 ? -1.001 -54.199 67.415 1.00 30.46 ? 675 LEU A O 1 ATOM 5043 C CB . LEU A 1 648 ? 0.896 -53.726 65.487 1.00 34.49 ? 675 LEU A CB 1 ATOM 5044 C CG . LEU A 1 648 ? 1.834 -53.668 64.279 1.00 32.78 ? 675 LEU A CG 1 ATOM 5045 C CD1 . LEU A 1 648 ? 3.245 -54.036 64.682 1.00 38.79 ? 675 LEU A CD1 1 ATOM 5046 C CD2 . LEU A 1 648 ? 1.344 -54.586 63.173 1.00 40.24 ? 675 LEU A CD2 1 ATOM 5047 N N . GLU A 1 649 ? -2.503 -52.752 66.568 1.00 39.31 ? 676 GLU A N 1 ATOM 5048 C CA . GLU A 1 649 ? -3.318 -52.690 67.780 1.00 38.79 ? 676 GLU A CA 1 ATOM 5049 C C . GLU A 1 649 ? -3.893 -54.042 68.200 1.00 37.52 ? 676 GLU A C 1 ATOM 5050 O O . GLU A 1 649 ? -4.154 -54.908 67.365 1.00 39.25 ? 676 GLU A O 1 ATOM 5051 C CB . GLU A 1 649 ? -4.453 -51.668 67.626 1.00 36.66 ? 676 GLU A CB 1 ATOM 5052 C CG . GLU A 1 649 ? -4.003 -50.233 67.368 1.00 33.30 ? 676 GLU A CG 1 ATOM 5053 C CD . GLU A 1 649 ? -3.881 -49.914 65.887 1.00 40.83 ? 676 GLU A CD 1 ATOM 5054 O OE1 . GLU A 1 649 ? -4.326 -48.821 65.465 1.00 38.48 ? 676 GLU A OE1 1 ATOM 5055 O OE2 . GLU A 1 649 ? -3.341 -50.760 65.143 1.00 41.58 1 676 GLU A OE2 1 ATOM 5056 N N . ASN A 1 650 ? -4.079 -54.200 69.508 1.00 36.43 ? 677 ASN A N 1 ATOM 5057 C CA . ASN A 1 650 ? -4.702 -55.385 70.095 1.00 37.69 ? 677 ASN A CA 1 ATOM 5058 C C . ASN A 1 650 ? -4.174 -56.727 69.585 1.00 38.71 ? 677 ASN A C 1 ATOM 5059 O O . ASN A 1 650 ? -4.944 -57.601 69.192 1.00 41.04 ? 677 ASN A O 1 ATOM 5060 C CB . ASN A 1 650 ? -6.227 -55.308 69.971 1.00 37.16 ? 677 ASN A CB 1 ATOM 5061 C CG . ASN A 1 650 ? -6.826 -54.201 70.826 1.00 36.09 ? 677 ASN A CG 1 ATOM 5062 O OD1 . ASN A 1 650 ? -6.140 -53.249 71.204 1.00 33.33 ? 677 ASN A OD1 1 ATOM 5063 N ND2 . ASN A 1 650 ? -8.110 -54.327 71.141 1.00 31.10 ? 677 ASN A ND2 1 ATOM 5064 N N . ASN A 1 651 ? -2.853 -56.873 69.586 1.00 43.20 ? 678 ASN A N 1 ATOM 5065 C CA . ASN A 1 651 ? -2.216 -58.147 69.273 1.00 46.45 ? 678 ASN A CA 1 ATOM 5066 C C . ASN A 1 651 ? -1.528 -58.696 70.506 1.00 42.97 ? 678 ASN A C 1 ATOM 5067 O O . ASN A 1 651 ? -1.874 -58.349 71.634 1.00 41.48 ? 678 ASN A O 1 ATOM 5068 C CB . ASN A 1 651 ? -1.169 -57.997 68.164 1.00 44.23 ? 678 ASN A CB 1 ATOM 5069 C CG . ASN A 1 651 ? -1.762 -57.550 66.850 1.00 48.09 ? 678 ASN A CG 1 ATOM 5070 O OD1 . ASN A 1 651 ? -2.863 -57.955 66.478 1.00 54.34 ? 678 ASN A OD1 1 ATOM 5071 N ND2 . ASN A 1 651 ? -1.029 -56.706 66.133 1.00 44.56 ? 678 ASN A ND2 1 ATOM 5072 N N . THR A 1 652 ? -0.541 -59.553 70.271 1.00 44.66 ? 679 THR A N 1 ATOM 5073 C CA . THR A 1 652 ? 0.298 -60.093 71.328 1.00 41.94 ? 679 THR A CA 1 ATOM 5074 C C . THR A 1 652 ? 1.735 -60.145 70.841 1.00 41.80 ? 679 THR A C 1 ATOM 5075 O O . THR A 1 652 ? 2.339 -61.216 70.800 1.00 42.33 ? 679 THR A O 1 ATOM 5076 C CB . THR A 1 652 ? -0.123 -61.519 71.723 1.00 42.65 ? 679 THR A CB 1 ATOM 5077 O OG1 . THR A 1 652 ? -0.188 -62.338 70.548 1.00 39.98 ? 679 THR A OG1 1 ATOM 5078 C CG2 . THR A 1 652 ? -1.479 -61.517 72.421 1.00 42.30 ? 679 THR A CG2 1 ATOM 5079 N N . LEU A 1 653 ? 2.276 -58.992 70.452 1.00 42.00 ? 680 LEU A N 1 ATOM 5080 C CA . LEU A 1 653 ? 3.673 -58.900 70.032 1.00 43.28 ? 680 LEU A CA 1 ATOM 5081 C C . LEU A 1 653 ? 4.582 -59.305 71.179 1.00 47.59 ? 680 LEU A C 1 ATOM 5082 O O . LEU A 1 653 ? 4.115 -59.572 72.277 1.00 48.38 ? 680 LEU A O 1 ATOM 5083 C CB . LEU A 1 653 ? 4.022 -57.478 69.596 1.00 43.14 ? 680 LEU A CB 1 ATOM 5084 C CG . LEU A 1 653 ? 4.035 -57.161 68.103 1.00 43.10 ? 680 LEU A CG 1 ATOM 5085 C CD1 . LEU A 1 653 ? 2.628 -57.155 67.542 1.00 43.38 ? 680 LEU A CD1 1 ATOM 5086 C CD2 . LEU A 1 653 ? 4.722 -55.829 67.866 1.00 40.64 ? 680 LEU A CD2 1 ATOM 5087 N N . LEU A 1 654 ? 5.882 -59.357 70.930 1.00 45.01 ? 681 LEU A N 1 ATOM 5088 C CA . LEU A 1 654 ? 6.816 -59.662 72.004 1.00 41.95 ? 681 LEU A CA 1 ATOM 5089 C C . LEU A 1 654 ? 7.959 -58.668 71.999 1.00 41.42 ? 681 LEU A C 1 ATOM 5090 O O . LEU A 1 654 ? 8.164 -57.934 72.966 1.00 49.14 ? 681 LEU A O 1 ATOM 5091 C CB . LEU A 1 654 ? 7.336 -61.097 71.894 1.00 44.34 ? 681 LEU A CB 1 ATOM 5092 C CG . LEU A 1 654 ? 6.332 -62.221 72.180 1.00 40.70 ? 681 LEU A CG 1 ATOM 5093 C CD1 . LEU A 1 654 ? 7.006 -63.575 72.041 1.00 40.84 ? 681 LEU A CD1 1 ATOM 5094 C CD2 . LEU A 1 654 ? 5.692 -62.077 73.557 1.00 32.02 ? 681 LEU A CD2 1 ATOM 5095 N N . ARG A 1 655 ? 8.698 -58.639 70.900 1.00 32.52 ? 682 ARG A N 1 ATOM 5096 C CA . ARG A 1 655 ? 9.790 -57.698 70.760 1.00 34.37 ? 682 ARG A CA 1 ATOM 5097 C C . ARG A 1 655 ? 9.622 -56.925 69.463 1.00 39.18 ? 682 ARG A C 1 ATOM 5098 O O . ARG A 1 655 ? 8.902 -57.351 68.561 1.00 44.62 ? 682 ARG A O 1 ATOM 5099 C CB . ARG A 1 655 ? 11.130 -58.432 70.780 1.00 38.38 ? 682 ARG A CB 1 ATOM 5100 C CG . ARG A 1 655 ? 12.286 -57.586 71.286 1.00 51.79 ? 682 ARG A CG 1 ATOM 5101 C CD . ARG A 1 655 ? 13.578 -58.390 71.387 1.00 67.11 ? 682 ARG A CD 1 ATOM 5102 N NE . ARG A 1 655 ? 13.435 -59.590 72.209 1.00 74.35 ? 682 ARG A NE 1 ATOM 5103 C CZ . ARG A 1 655 ? 13.519 -59.605 73.537 1.00 73.94 ? 682 ARG A CZ 1 ATOM 5104 N NH1 . ARG A 1 655 ? 13.736 -58.479 74.204 1.00 71.16 1 682 ARG A NH1 1 ATOM 5105 N NH2 . ARG A 1 655 ? 13.378 -60.747 74.200 1.00 65.24 ? 682 ARG A NH2 1 ATOM 5106 N N . LEU A 1 656 ? 10.279 -55.778 69.376 1.00 41.64 ? 683 LEU A N 1 ATOM 5107 C CA . LEU A 1 656 ? 10.266 -54.999 68.151 1.00 45.29 ? 683 LEU A CA 1 ATOM 5108 C C . LEU A 1 656 ? 11.539 -55.246 67.349 1.00 47.53 ? 683 LEU A C 1 ATOM 5109 O O . LEU A 1 656 ? 12.607 -55.473 67.920 1.00 47.59 ? 683 LEU A O 1 ATOM 5110 C CB . LEU A 1 656 ? 10.112 -53.512 68.469 1.00 44.71 ? 683 LEU A CB 1 ATOM 5111 C CG . LEU A 1 656 ? 8.722 -53.114 68.964 1.00 48.14 ? 683 LEU A CG 1 ATOM 5112 C CD1 . LEU A 1 656 ? 8.722 -51.677 69.452 1.00 48.34 ? 683 LEU A CD1 1 ATOM 5113 C CD2 . LEU A 1 656 ? 7.686 -53.313 67.859 1.00 44.93 ? 683 LEU A CD2 1 ATOM 5114 N N . PRO A 1 657 ? 11.424 -55.220 66.015 1.00 45.24 ? 684 PRO A N 1 ATOM 5115 C CA . PRO A 1 657 ? 12.591 -55.350 65.136 1.00 49.01 ? 684 PRO A CA 1 ATOM 5116 C C . PRO A 1 657 ? 13.501 -54.129 65.224 1.00 45.18 ? 684 PRO A C 1 ATOM 5117 O O . PRO A 1 657 ? 13.142 -53.142 65.860 1.00 46.82 ? 684 PRO A O 1 ATOM 5118 C CB . PRO A 1 657 ? 11.969 -55.457 63.740 1.00 54.75 ? 684 PRO A CB 1 ATOM 5119 C CG . PRO A 1 657 ? 10.619 -54.839 63.871 1.00 53.47 ? 684 PRO A CG 1 ATOM 5120 C CD . PRO A 1 657 ? 10.164 -55.159 65.258 1.00 48.91 ? 684 PRO A CD 1 ATOM 5121 N N . SER A 1 658 ? 14.666 -54.197 64.589 1.00 45.12 ? 685 SER A N 1 ATOM 5122 C CA . SER A 1 658 ? 15.630 -53.105 64.656 1.00 44.65 ? 685 SER A CA 1 ATOM 5123 C C . SER A 1 658 ? 15.150 -51.900 63.863 1.00 48.41 ? 685 SER A C 1 ATOM 5124 O O . SER A 1 658 ? 14.124 -51.954 63.187 1.00 53.45 ? 685 SER A O 1 ATOM 5125 C CB . SER A 1 658 ? 16.988 -53.554 64.120 1.00 48.08 ? 685 SER A CB 1 ATOM 5126 O OG . SER A 1 658 ? 16.945 -53.729 62.715 1.00 48.63 ? 685 SER A OG 1 ATOM 5127 N N . ALA A 1 659 ? 15.906 -50.812 63.944 1.00 44.91 ? 686 ALA A N 1 ATOM 5128 C CA . ALA A 1 659 ? 15.589 -49.611 63.189 1.00 45.43 ? 686 ALA A CA 1 ATOM 5129 C C . ALA A 1 659 ? 15.990 -49.785 61.733 1.00 48.68 ? 686 ALA A C 1 ATOM 5130 O O . ALA A 1 659 ? 15.527 -49.051 60.860 1.00 47.31 ? 686 ALA A O 1 ATOM 5131 C CB . ALA A 1 659 ? 16.298 -48.413 63.787 1.00 52.74 ? 686 ALA A CB 1 ATOM 5132 N N . ASN A 1 660 ? 16.857 -50.763 61.481 1.00 48.92 ? 687 ASN A N 1 ATOM 5133 C CA . ASN A 1 660 ? 17.389 -51.000 60.144 1.00 46.59 ? 687 ASN A CA 1 ATOM 5134 C C . ASN A 1 660 ? 16.579 -52.009 59.347 1.00 46.29 ? 687 ASN A C 1 ATOM 5135 O O . ASN A 1 660 ? 16.926 -52.336 58.214 1.00 47.65 ? 687 ASN A O 1 ATOM 5136 C CB . ASN A 1 660 ? 18.852 -51.439 60.215 1.00 52.65 ? 687 ASN A CB 1 ATOM 5137 C CG . ASN A 1 660 ? 19.805 -50.353 59.763 1.00 53.70 ? 687 ASN A CG 1 ATOM 5138 O OD1 . ASN A 1 660 ? 20.706 -49.950 60.502 1.00 47.30 ? 687 ASN A OD1 1 ATOM 5139 N ND2 . ASN A 1 660 ? 19.609 -49.869 58.542 1.00 48.83 ? 687 ASN A ND2 1 ATOM 5140 N N . THR A 1 661 ? 15.502 -52.505 59.947 1.00 47.99 ? 688 THR A N 1 ATOM 5141 C CA . THR A 1 661 ? 14.591 -53.399 59.248 1.00 48.98 ? 688 THR A CA 1 ATOM 5142 C C . THR A 1 661 ? 13.931 -52.650 58.098 1.00 51.27 ? 688 THR A C 1 ATOM 5143 O O . THR A 1 661 ? 13.219 -51.672 58.320 1.00 52.24 ? 688 THR A O 1 ATOM 5144 C CB . THR A 1 661 ? 13.501 -53.944 60.185 1.00 48.79 ? 688 THR A CB 1 ATOM 5145 O OG1 . THR A 1 661 ? 14.109 -54.647 61.277 1.00 48.51 ? 688 THR A OG1 1 ATOM 5146 C CG2 . THR A 1 661 ? 12.575 -54.886 59.430 1.00 46.81 ? 688 THR A CG2 1 ATOM 5147 N N . PRO A 1 662 ? 14.178 -53.103 56.860 1.00 49.56 ? 689 PRO A N 1 ATOM 5148 C CA . PRO A 1 662 ? 13.647 -52.454 55.656 1.00 50.09 ? 689 PRO A CA 1 ATOM 5149 C C . PRO A 1 662 ? 12.125 -52.471 55.642 1.00 49.69 ? 689 PRO A C 1 ATOM 5150 O O . PRO A 1 662 ? 11.510 -53.418 56.135 1.00 48.92 ? 689 PRO A O 1 ATOM 5151 C CB . PRO A 1 662 ? 14.194 -53.322 54.522 1.00 56.28 ? 689 PRO A CB 1 ATOM 5152 C CG . PRO A 1 662 ? 15.377 -54.021 55.114 1.00 55.82 ? 689 PRO A CG 1 ATOM 5153 C CD . PRO A 1 662 ? 15.000 -54.277 56.533 1.00 47.59 ? 689 PRO A CD 1 ATOM 5154 N N . GLY A 1 663 ? 11.528 -51.427 55.079 1.00 50.27 ? 690 GLY A N 1 ATOM 5155 C CA . GLY A 1 663 ? 10.093 -51.240 55.163 1.00 50.43 ? 690 GLY A CA 1 ATOM 5156 C C . GLY A 1 663 ? 9.761 -50.619 56.505 1.00 51.30 ? 690 GLY A C 1 ATOM 5157 O O . GLY A 1 663 ? 9.288 -49.485 56.582 1.00 52.85 ? 690 GLY A O 1 ATOM 5158 N N . TYR A 1 664 ? 10.034 -51.374 57.564 1.00 50.59 ? 691 TYR A N 1 ATOM 5159 C CA . TYR A 1 664 ? 9.874 -50.920 58.942 1.00 48.83 ? 691 TYR A CA 1 ATOM 5160 C C . TYR A 1 664 ? 10.666 -49.634 59.215 1.00 45.06 ? 691 TYR A C 1 ATOM 5161 O O . TYR A 1 664 ? 10.216 -48.769 59.965 1.00 40.23 ? 691 TYR A O 1 ATOM 5162 C CB . TYR A 1 664 ? 10.312 -52.050 59.887 1.00 53.29 ? 691 TYR A CB 1 ATOM 5163 C CG . TYR A 1 664 ? 10.194 -51.769 61.372 1.00 51.73 ? 691 TYR A CG 1 ATOM 5164 C CD1 . TYR A 1 664 ? 9.010 -52.021 62.055 1.00 45.31 ? 691 TYR A CD1 1 ATOM 5165 C CD2 . TYR A 1 664 ? 11.280 -51.288 62.097 1.00 48.58 ? 691 TYR A CD2 1 ATOM 5166 C CE1 . TYR A 1 664 ? 8.903 -51.779 63.414 1.00 46.26 ? 691 TYR A CE1 1 ATOM 5167 C CE2 . TYR A 1 664 ? 11.182 -51.041 63.453 1.00 47.61 ? 691 TYR A CE2 1 ATOM 5168 C CZ . TYR A 1 664 ? 9.993 -51.289 64.107 1.00 52.68 ? 691 TYR A CZ 1 ATOM 5169 O OH . TYR A 1 664 ? 9.898 -51.045 65.459 1.00 52.21 ? 691 TYR A OH 1 ATOM 5170 N N . GLU A 1 665 ? 11.832 -49.507 58.584 1.00 45.85 ? 692 GLU A N 1 ATOM 5171 C CA . GLU A 1 665 ? 12.739 -48.382 58.825 1.00 47.93 ? 692 GLU A CA 1 ATOM 5172 C C . GLU A 1 665 ? 12.186 -47.023 58.393 1.00 53.47 ? 692 GLU A C 1 ATOM 5173 O O . GLU A 1 665 ? 12.743 -45.981 58.751 1.00 48.41 ? 692 GLU A O 1 ATOM 5174 C CB . GLU A 1 665 ? 14.078 -48.620 58.122 1.00 45.29 ? 692 GLU A CB 1 ATOM 5175 C CG . GLU A 1 665 ? 13.968 -48.741 56.612 1.00 49.50 ? 692 GLU A CG 1 ATOM 5176 C CD . GLU A 1 665 ? 15.318 -48.769 55.932 1.00 47.27 ? 692 GLU A CD 1 ATOM 5177 O OE1 . GLU A 1 665 ? 16.342 -48.692 56.643 1.00 48.04 ? 692 GLU A OE1 1 ATOM 5178 O OE2 . GLU A 1 665 ? 15.356 -48.866 54.688 1.00 46.59 1 692 GLU A OE2 1 ATOM 5179 N N . SER A 1 666 ? 11.103 -47.034 57.620 1.00 54.01 ? 693 SER A N 1 ATOM 5180 C CA . SER A 1 666 ? 10.540 -45.801 57.074 1.00 50.57 ? 693 SER A CA 1 ATOM 5181 C C . SER A 1 666 ? 9.254 -45.390 57.782 1.00 42.13 ? 693 SER A C 1 ATOM 5182 O O . SER A 1 666 ? 8.601 -44.426 57.387 1.00 37.99 ? 693 SER A O 1 ATOM 5183 C CB . SER A 1 666 ? 10.289 -45.955 55.575 1.00 48.43 ? 693 SER A CB 1 ATOM 5184 O OG . SER A 1 666 ? 11.485 -46.306 54.899 1.00 54.65 ? 693 SER A OG 1 ATOM 5185 N N . VAL A 1 667 ? 8.908 -46.128 58.833 1.00 45.06 ? 694 VAL A N 1 ATOM 5186 C CA . VAL A 1 667 ? 7.699 -45.877 59.615 1.00 40.32 ? 694 VAL A CA 1 ATOM 5187 C C . VAL A 1 667 ? 7.737 -44.520 60.317 1.00 38.84 ? 694 VAL A C 1 ATOM 5188 O O . VAL A 1 667 ? 8.762 -44.128 60.875 1.00 39.34 ? 694 VAL A O 1 ATOM 5189 C CB . VAL A 1 667 ? 7.471 -46.996 60.670 1.00 33.65 ? 694 VAL A CB 1 ATOM 5190 C CG1 . VAL A 1 667 ? 6.475 -46.558 61.726 1.00 31.97 ? 694 VAL A CG1 1 ATOM 5191 C CG2 . VAL A 1 667 ? 7.004 -48.278 60.006 1.00 32.02 ? 694 VAL A CG2 1 ATOM 5192 N N . THR A 1 668 ? 6.618 -43.802 60.271 1.00 34.85 ? 695 THR A N 1 ATOM 5193 C CA . THR A 1 668 ? 6.473 -42.571 61.031 1.00 33.55 ? 695 THR A CA 1 ATOM 5194 C C . THR A 1 668 ? 5.585 -42.794 62.249 1.00 31.68 ? 695 THR A C 1 ATOM 5195 O O . THR A 1 668 ? 5.758 -42.150 63.282 1.00 36.03 ? 695 THR A O 1 ATOM 5196 C CB . THR A 1 668 ? 5.866 -41.446 60.181 1.00 30.17 ? 695 THR A CB 1 ATOM 5197 O OG1 . THR A 1 668 ? 4.625 -41.891 59.625 1.00 31.73 ? 695 THR A OG1 1 ATOM 5198 C CG2 . THR A 1 668 ? 6.807 -41.057 59.063 1.00 27.49 ? 695 THR A CG2 1 ATOM 5199 N N . SER A 1 669 ? 4.636 -43.711 62.133 1.00 25.13 ? 696 SER A N 1 ATOM 5200 C CA . SER A 1 669 ? 3.676 -43.923 63.207 1.00 28.24 ? 696 SER A CA 1 ATOM 5201 C C . SER A 1 669 ? 3.591 -45.389 63.638 1.00 32.44 ? 696 SER A C 1 ATOM 5202 O O . SER A 1 669 ? 3.542 -46.293 62.804 1.00 32.72 ? 696 SER A O 1 ATOM 5203 C CB . SER A 1 669 ? 2.304 -43.393 62.796 1.00 29.86 ? 696 SER A CB 1 ATOM 5204 O OG . SER A 1 669 ? 1.414 -43.401 63.893 1.00 24.13 ? 696 SER A OG 1 ATOM 5205 N N . LEU A 1 670 ? 3.559 -45.613 64.949 1.00 32.57 ? 697 LEU A N 1 ATOM 5206 C CA . LEU A 1 670 ? 3.695 -46.955 65.510 1.00 29.14 ? 697 LEU A CA 1 ATOM 5207 C C . LEU A 1 670 ? 2.620 -47.225 66.560 1.00 26.53 ? 697 LEU A C 1 ATOM 5208 O O . LEU A 1 670 ? 2.812 -46.943 67.742 1.00 25.48 ? 697 LEU A O 1 ATOM 5209 C CB . LEU A 1 670 ? 5.084 -47.102 66.132 1.00 28.25 ? 697 LEU A CB 1 ATOM 5210 C CG . LEU A 1 670 ? 5.714 -48.491 66.185 1.00 30.07 ? 697 LEU A CG 1 ATOM 5211 C CD1 . LEU A 1 670 ? 5.951 -49.014 64.779 1.00 30.16 ? 697 LEU A CD1 1 ATOM 5212 C CD2 . LEU A 1 670 ? 7.015 -48.448 66.976 1.00 28.01 ? 697 LEU A CD2 1 ATOM 5213 N N . HIS A 1 671 ? 1.496 -47.787 66.125 1.00 28.45 ? 698 HIS A N 1 ATOM 5214 C CA . HIS A 1 671 ? 0.320 -47.935 66.980 1.00 29.26 ? 698 HIS A CA 1 ATOM 5215 C C . HIS A 1 671 ? 0.196 -49.333 67.555 1.00 35.45 ? 698 HIS A C 1 ATOM 5216 O O . HIS A 1 671 ? -0.552 -50.159 67.030 1.00 34.19 ? 698 HIS A O 1 ATOM 5217 C CB . HIS A 1 671 ? -0.927 -47.603 66.179 1.00 27.75 ? 698 HIS A CB 1 ATOM 5218 C CG . HIS A 1 671 ? -0.809 -46.331 65.408 1.00 32.57 ? 698 HIS A CG 1 ATOM 5219 N ND1 . HIS A 1 671 ? -1.437 -45.167 65.798 1.00 35.28 ? 698 HIS A ND1 1 ATOM 5220 C CD2 . HIS A 1 671 ? -0.114 -46.027 64.287 1.00 29.89 ? 698 HIS A CD2 1 ATOM 5221 C CE1 . HIS A 1 671 ? -1.147 -44.207 64.939 1.00 34.29 ? 698 HIS A CE1 1 ATOM 5222 N NE2 . HIS A 1 671 ? -0.343 -44.702 64.014 1.00 29.62 ? 698 HIS A NE2 1 ATOM 5223 N N . LEU A 1 672 ? 0.911 -49.580 68.649 1.00 36.93 ? 699 LEU A N 1 ATOM 5224 C CA . LEU A 1 672 ? 1.081 -50.933 69.168 1.00 31.34 ? 699 LEU A CA 1 ATOM 5225 C C . LEU A 1 672 ? 0.234 -51.216 70.404 1.00 27.08 ? 699 LEU A C 1 ATOM 5226 O O . LEU A 1 672 ? 0.451 -52.213 71.085 1.00 30.13 ? 699 LEU A O 1 ATOM 5227 C CB . LEU A 1 672 ? 2.557 -51.184 69.485 1.00 27.89 ? 699 LEU A CB 1 ATOM 5228 C CG . LEU A 1 672 ? 3.579 -50.624 68.491 1.00 29.50 ? 699 LEU A CG 1 ATOM 5229 C CD1 . LEU A 1 672 ? 4.995 -50.919 68.959 1.00 36.90 ? 699 LEU A CD1 1 ATOM 5230 C CD2 . LEU A 1 672 ? 3.359 -51.172 67.090 1.00 29.20 ? 699 LEU A CD2 1 ATOM 5231 N N . ALA A 1 673 ? -0.728 -50.345 70.684 1.00 24.03 ? 700 ALA A N 1 ATOM 5232 C CA . ALA A 1 673 ? -1.580 -50.488 71.861 1.00 27.28 ? 700 ALA A CA 1 ATOM 5233 C C . ALA A 1 673 ? -2.187 -51.882 71.992 1.00 31.60 ? 700 ALA A C 1 ATOM 5234 O O . ALA A 1 673 ? -2.459 -52.545 70.996 1.00 36.13 ? 700 ALA A O 1 ATOM 5235 C CB . ALA A 1 673 ? -2.676 -49.444 71.843 1.00 34.34 ? 700 ALA A CB 1 ATOM 5236 N N . GLY A 1 674 ? -2.388 -52.320 73.230 1.00 35.94 ? 701 GLY A N 1 ATOM 5237 C CA . GLY A 1 674 ? -2.968 -53.625 73.495 1.00 39.30 ? 701 GLY A CA 1 ATOM 5238 C C . GLY A 1 674 ? -2.071 -54.777 73.079 1.00 39.64 ? 701 GLY A C 1 ATOM 5239 O O . GLY A 1 674 ? -2.537 -55.760 72.502 1.00 38.98 ? 701 GLY A O 1 ATOM 5240 N N . ASN A 1 675 ? -0.781 -54.660 73.376 1.00 34.53 ? 702 ASN A N 1 ATOM 5241 C CA . ASN A 1 675 ? 0.171 -55.706 73.027 1.00 37.32 ? 702 ASN A CA 1 ATOM 5242 C C . ASN A 1 675 ? 1.001 -56.201 74.205 1.00 45.27 ? 702 ASN A C 1 ATOM 5243 O O . ASN A 1 675 ? 0.728 -55.860 75.356 1.00 45.18 ? 702 ASN A O 1 ATOM 5244 C CB . ASN A 1 675 ? 1.092 -55.239 71.905 1.00 37.84 ? 702 ASN A CB 1 ATOM 5245 C CG . ASN A 1 675 ? 0.666 -55.758 70.557 1.00 37.32 ? 702 ASN A CG 1 ATOM 5246 O OD1 . ASN A 1 675 ? 0.936 -56.907 70.211 1.00 34.82 ? 702 ASN A OD1 1 ATOM 5247 N ND2 . ASN A 1 675 ? -0.003 -54.915 69.783 1.00 41.79 ? 702 ASN A ND2 1 ATOM 5248 N N . ASN A 1 676 ? 2.004 -57.025 73.902 1.00 47.20 ? 703 ASN A N 1 ATOM 5249 C CA . ASN A 1 676 ? 2.930 -57.533 74.905 1.00 43.55 ? 703 ASN A CA 1 ATOM 5250 C C . ASN A 1 676 ? 4.358 -57.090 74.615 1.00 51.80 ? 703 ASN A C 1 ATOM 5251 O O . ASN A 1 676 ? 5.159 -57.875 74.109 1.00 54.98 ? 703 ASN A O 1 ATOM 5252 C CB . ASN A 1 676 ? 2.938 -59.062 74.937 1.00 42.55 ? 703 ASN A CB 1 ATOM 5253 C CG . ASN A 1 676 ? 1.579 -59.669 75.178 1.00 47.77 ? 703 ASN A CG 1 ATOM 5254 O OD1 . ASN A 1 676 ? 0.544 -59.020 75.038 1.00 49.71 ? 703 ASN A OD1 1 ATOM 5255 N ND2 . ASN A 1 676 ? 1.582 -60.950 75.531 1.00 54.97 ? 703 ASN A ND2 1 ATOM 5256 N N . LEU A 1 677 ? 4.688 -55.843 74.926 1.00 49.76 ? 704 LEU A N 1 ATOM 5257 C CA . LEU A 1 677 ? 6.081 -55.417 74.865 1.00 48.14 ? 704 LEU A CA 1 ATOM 5258 C C . LEU A 1 677 ? 6.584 -55.200 76.289 1.00 44.63 ? 704 LEU A C 1 ATOM 5259 O O . LEU A 1 677 ? 5.919 -54.543 77.086 1.00 42.15 ? 704 LEU A O 1 ATOM 5260 C CB . LEU A 1 677 ? 6.227 -54.147 74.027 1.00 43.86 ? 704 LEU A CB 1 ATOM 5261 C CG . LEU A 1 677 ? 5.680 -54.211 72.598 1.00 40.28 ? 704 LEU A CG 1 ATOM 5262 C CD1 . LEU A 1 677 ? 6.044 -52.952 71.822 1.00 36.54 ? 704 LEU A CD1 1 ATOM 5263 C CD2 . LEU A 1 677 ? 6.171 -55.456 71.877 1.00 43.84 ? 704 LEU A CD2 1 ATOM 5264 N N . THR A 1 678 ? 7.745 -55.762 76.615 1.00 44.83 ? 705 THR A N 1 ATOM 5265 C CA . THR A 1 678 ? 8.244 -55.708 77.989 1.00 45.35 ? 705 THR A CA 1 ATOM 5266 C C . THR A 1 678 ? 9.458 -54.797 78.138 1.00 39.83 ? 705 THR A C 1 ATOM 5267 O O . THR A 1 678 ? 9.800 -54.376 79.244 1.00 41.72 ? 705 THR A O 1 ATOM 5268 C CB . THR A 1 678 ? 8.612 -57.101 78.513 1.00 38.27 ? 705 THR A CB 1 ATOM 5269 O OG1 . THR A 1 678 ? 9.906 -57.469 78.017 1.00 35.48 ? 705 THR A OG1 1 ATOM 5270 C CG2 . THR A 1 678 ? 7.574 -58.128 78.073 1.00 40.83 ? 705 THR A CG2 1 ATOM 5271 N N . SER A 1 679 ? 10.107 -54.498 77.022 1.00 32.90 ? 706 SER A N 1 ATOM 5272 C CA . SER A 1 679 ? 11.245 -53.594 77.027 1.00 35.21 ? 706 SER A CA 1 ATOM 5273 C C . SER A 1 679 ? 11.468 -53.040 75.628 1.00 43.11 ? 706 SER A C 1 ATOM 5274 O O . SER A 1 679 ? 11.397 -53.770 74.639 1.00 49.81 ? 706 SER A O 1 ATOM 5275 C CB . SER A 1 679 ? 12.502 -54.307 77.533 1.00 42.86 ? 706 SER A CB 1 ATOM 5276 O OG . SER A 1 679 ? 12.759 -55.493 76.799 1.00 48.54 ? 706 SER A OG 1 ATOM 5277 N N . ILE A 1 680 ? 11.731 -51.742 75.548 1.00 38.68 ? 707 ILE A N 1 ATOM 5278 C CA . ILE A 1 680 ? 11.902 -51.082 74.264 1.00 33.21 ? 707 ILE A CA 1 ATOM 5279 C C . ILE A 1 680 ? 13.290 -50.468 74.153 1.00 37.91 ? 707 ILE A C 1 ATOM 5280 O O . ILE A 1 680 ? 13.614 -49.519 74.866 1.00 41.50 ? 707 ILE A O 1 ATOM 5281 C CB . ILE A 1 680 ? 10.864 -49.966 74.073 1.00 29.08 ? 707 ILE A CB 1 ATOM 5282 C CG1 . ILE A 1 680 ? 9.452 -50.510 74.264 1.00 24.64 ? 707 ILE A CG1 1 ATOM 5283 C CG2 . ILE A 1 680 ? 11.003 -49.345 72.701 1.00 38.11 ? 707 ILE A CG2 1 ATOM 5284 C CD1 . ILE A 1 680 ? 9.081 -51.572 73.268 1.00 36.48 ? 707 ILE A CD1 1 ATOM 5285 N N . ASP A 1 681 ? 14.110 -51.011 73.262 1.00 38.75 ? 708 ASP A N 1 ATOM 5286 C CA . ASP A 1 681 ? 15.435 -50.451 73.030 1.00 44.93 ? 708 ASP A CA 1 ATOM 5287 C C . ASP A 1 681 ? 15.320 -49.251 72.098 1.00 39.26 ? 708 ASP A C 1 ATOM 5288 O O . ASP A 1 681 ? 14.417 -49.192 71.268 1.00 37.67 ? 708 ASP A O 1 ATOM 5289 C CB . ASP A 1 681 ? 16.379 -51.504 72.438 1.00 51.82 ? 708 ASP A CB 1 ATOM 5290 C CG . ASP A 1 681 ? 17.819 -51.018 72.352 1.00 54.92 ? 708 ASP A CG 1 ATOM 5291 O OD1 . ASP A 1 681 ? 18.222 -50.207 73.213 1.00 54.99 ? 708 ASP A OD1 1 ATOM 5292 O OD2 . ASP A 1 681 ? 18.547 -51.442 71.426 1.00 52.69 1 708 ASP A OD2 1 ATOM 5293 N N . VAL A 1 682 ? 16.239 -48.299 72.236 1.00 41.26 ? 709 VAL A N 1 ATOM 5294 C CA . VAL A 1 682 ? 16.227 -47.088 71.421 1.00 38.56 ? 709 VAL A CA 1 ATOM 5295 C C . VAL A 1 682 ? 16.606 -47.388 69.968 1.00 49.39 ? 709 VAL A C 1 ATOM 5296 O O . VAL A 1 682 ? 16.526 -46.518 69.096 1.00 48.90 ? 709 VAL A O 1 ATOM 5297 C CB . VAL A 1 682 ? 17.175 -46.019 71.996 1.00 35.11 ? 709 VAL A CB 1 ATOM 5298 C CG1 . VAL A 1 682 ? 18.605 -46.265 71.529 1.00 42.87 ? 709 VAL A CG1 1 ATOM 5299 C CG2 . VAL A 1 682 ? 16.712 -44.629 71.602 1.00 37.53 ? 709 VAL A CG2 1 ATOM 5300 N N . ASP A 1 683 ? 17.013 -48.627 69.711 1.00 50.19 ? 710 ASP A N 1 ATOM 5301 C CA . ASP A 1 683 ? 17.369 -49.051 68.365 1.00 45.79 ? 710 ASP A CA 1 ATOM 5302 C C . ASP A 1 683 ? 16.219 -49.806 67.727 1.00 48.91 ? 710 ASP A C 1 ATOM 5303 O O . ASP A 1 683 ? 16.210 -50.030 66.518 1.00 61.19 ? 710 ASP A O 1 ATOM 5304 C CB . ASP A 1 683 ? 18.627 -49.916 68.390 1.00 50.09 ? 710 ASP A CB 1 ATOM 5305 C CG . ASP A 1 683 ? 19.857 -49.136 68.807 1.00 58.41 ? 710 ASP A CG 1 ATOM 5306 O OD1 . ASP A 1 683 ? 20.164 -48.111 68.158 1.00 47.01 ? 710 ASP A OD1 1 ATOM 5307 O OD2 . ASP A 1 683 ? 20.507 -49.539 69.796 1.00 67.01 1 710 ASP A OD2 1 ATOM 5308 N N . GLN A 1 684 ? 15.244 -50.197 68.540 1.00 42.39 ? 711 GLN A N 1 ATOM 5309 C CA . GLN A 1 684 ? 14.053 -50.858 68.021 1.00 48.07 ? 711 GLN A CA 1 ATOM 5310 C C . GLN A 1 684 ? 13.060 -49.836 67.459 1.00 50.16 ? 711 GLN A C 1 ATOM 5311 O O . GLN A 1 684 ? 11.982 -50.198 66.981 1.00 49.47 ? 711 GLN A O 1 ATOM 5312 C CB . GLN A 1 684 ? 13.392 -51.711 69.105 1.00 39.77 ? 711 GLN A CB 1 ATOM 5313 C CG . GLN A 1 684 ? 14.292 -52.792 69.671 1.00 41.20 ? 711 GLN A CG 1 ATOM 5314 C CD . GLN A 1 684 ? 13.613 -53.607 70.753 1.00 45.48 ? 711 GLN A CD 1 ATOM 5315 O OE1 . GLN A 1 684 ? 12.417 -53.460 70.997 1.00 46.73 ? 711 GLN A OE1 1 ATOM 5316 N NE2 . GLN A 1 684 ? 14.376 -54.472 71.411 1.00 50.92 ? 711 GLN A NE2 1 ATOM 5317 N N . LEU A 1 685 ? 13.437 -48.561 67.513 1.00 41.86 ? 712 LEU A N 1 ATOM 5318 C CA . LEU A 1 685 ? 12.562 -47.478 67.079 1.00 40.38 ? 712 LEU A CA 1 ATOM 5319 C C . LEU A 1 685 ? 13.061 -46.879 65.767 1.00 43.19 ? 712 LEU A C 1 ATOM 5320 O O . LEU A 1 685 ? 14.264 -46.688 65.597 1.00 41.81 ? 712 LEU A O 1 ATOM 5321 C CB . LEU A 1 685 ? 12.474 -46.399 68.165 1.00 38.99 ? 712 LEU A CB 1 ATOM 5322 C CG . LEU A 1 685 ? 12.067 -46.862 69.571 1.00 33.67 ? 712 LEU A CG 1 ATOM 5323 C CD1 . LEU A 1 685 ? 12.148 -45.723 70.577 1.00 25.37 ? 712 LEU A CD1 1 ATOM 5324 C CD2 . LEU A 1 685 ? 10.677 -47.476 69.576 1.00 29.88 ? 712 LEU A CD2 1 ATOM 5325 N N . PRO A 1 686 ? 12.131 -46.594 64.834 1.00 45.12 ? 713 PRO A N 1 ATOM 5326 C CA . PRO A 1 686 ? 12.402 -46.056 63.492 1.00 43.38 ? 713 PRO A CA 1 ATOM 5327 C C . PRO A 1 686 ? 12.909 -44.618 63.495 1.00 41.15 ? 713 PRO A C 1 ATOM 5328 O O . PRO A 1 686 ? 12.512 -43.829 64.346 1.00 42.55 ? 713 PRO A O 1 ATOM 5329 C CB . PRO A 1 686 ? 11.030 -46.111 62.809 1.00 38.37 ? 713 PRO A CB 1 ATOM 5330 C CG . PRO A 1 686 ? 10.259 -47.123 63.576 1.00 39.22 ? 713 PRO A CG 1 ATOM 5331 C CD . PRO A 1 686 ? 10.713 -46.957 64.990 1.00 44.02 ? 713 PRO A CD 1 ATOM 5332 N N . THR A 1 687 ? 13.768 -44.293 62.533 1.00 49.30 ? 714 THR A N 1 ATOM 5333 C CA . THR A 1 687 ? 14.343 -42.956 62.405 1.00 53.41 ? 714 THR A CA 1 ATOM 5334 C C . THR A 1 687 ? 13.273 -41.904 62.125 1.00 48.64 ? 714 THR A C 1 ATOM 5335 O O . THR A 1 687 ? 13.271 -40.830 62.723 1.00 49.54 ? 714 THR A O 1 ATOM 5336 C CB . THR A 1 687 ? 15.381 -42.900 61.260 1.00 63.75 ? 714 THR A CB 1 ATOM 5337 O OG1 . THR A 1 687 ? 16.345 -43.949 61.420 1.00 67.65 ? 714 THR A OG1 1 ATOM 5338 C CG2 . THR A 1 687 ? 16.090 -41.549 61.237 1.00 51.58 ? 714 THR A CG2 1 ATOM 5339 N N . ASN A 1 688 ? 12.367 -42.223 61.208 1.00 45.21 ? 715 ASN A N 1 ATOM 5340 C CA . ASN A 1 688 ? 11.328 -41.287 60.795 1.00 47.14 ? 715 ASN A CA 1 ATOM 5341 C C . ASN A 1 688 ? 10.123 -41.247 61.739 1.00 46.31 ? 715 ASN A C 1 ATOM 5342 O O . ASN A 1 688 ? 9.081 -40.687 61.397 1.00 42.94 ? 715 ASN A O 1 ATOM 5343 C CB . ASN A 1 688 ? 10.864 -41.610 59.369 1.00 51.42 ? 715 ASN A CB 1 ATOM 5344 C CG . ASN A 1 688 ? 11.777 -41.021 58.309 1.00 56.95 ? 715 ASN A CG 1 ATOM 5345 O OD1 . ASN A 1 688 ? 12.736 -40.316 58.625 1.00 54.97 ? 715 ASN A OD1 1 ATOM 5346 N ND2 . ASN A 1 688 ? 11.484 -41.310 57.042 1.00 54.15 ? 715 ASN A ND2 1 ATOM 5347 N N . LEU A 1 689 ? 10.268 -41.830 62.926 1.00 41.62 ? 716 LEU A N 1 ATOM 5348 C CA . LEU A 1 689 ? 9.144 -41.959 63.850 1.00 36.59 ? 716 LEU A CA 1 ATOM 5349 C C . LEU A 1 689 ? 8.654 -40.603 64.347 1.00 36.42 ? 716 LEU A C 1 ATOM 5350 O O . LEU A 1 689 ? 9.449 -39.684 64.541 1.00 35.87 ? 716 LEU A O 1 ATOM 5351 C CB . LEU A 1 689 ? 9.510 -42.854 65.034 1.00 35.98 ? 716 LEU A CB 1 ATOM 5352 C CG . LEU A 1 689 ? 8.319 -43.453 65.785 1.00 34.08 ? 716 LEU A CG 1 ATOM 5353 C CD1 . LEU A 1 689 ? 7.514 -44.359 64.867 1.00 33.19 ? 716 LEU A CD1 1 ATOM 5354 C CD2 . LEU A 1 689 ? 8.769 -44.210 67.023 1.00 32.70 ? 716 LEU A CD2 1 ATOM 5355 N N . THR A 1 690 ? 7.339 -40.489 64.537 1.00 32.55 ? 717 THR A N 1 ATOM 5356 C CA . THR A 1 690 ? 6.725 -39.255 65.018 1.00 27.92 ? 717 THR A CA 1 ATOM 5357 C C . THR A 1 690 ? 5.627 -39.542 66.028 1.00 25.34 ? 717 THR A C 1 ATOM 5358 O O . THR A 1 690 ? 5.225 -38.666 66.787 1.00 29.56 ? 717 THR A O 1 ATOM 5359 C CB . THR A 1 690 ? 6.127 -38.417 63.870 1.00 32.97 ? 717 THR A CB 1 ATOM 5360 O OG1 . THR A 1 690 ? 5.793 -37.115 64.361 1.00 41.44 ? 717 THR A OG1 1 ATOM 5361 C CG2 . THR A 1 690 ? 4.868 -39.073 63.304 1.00 30.49 ? 717 THR A CG2 1 ATOM 5362 N N . HIS A 1 691 ? 5.134 -40.772 66.026 1.00 23.62 ? 718 HIS A N 1 ATOM 5363 C CA . HIS A 1 691 ? 4.135 -41.187 66.997 1.00 25.49 ? 718 HIS A CA 1 ATOM 5364 C C . HIS A 1 691 ? 4.585 -42.509 67.583 1.00 25.43 ? 718 HIS A C 1 ATOM 5365 O O . HIS A 1 691 ? 5.368 -43.232 66.969 1.00 26.29 ? 718 HIS A O 1 ATOM 5366 C CB . HIS A 1 691 ? 2.761 -41.331 66.337 1.00 31.77 ? 718 HIS A CB 1 ATOM 5367 C CG . HIS A 1 691 ? 1.626 -41.481 67.306 1.00 28.59 ? 718 HIS A CG 1 ATOM 5368 N ND1 . HIS A 1 691 ? 1.489 -40.687 68.426 1.00 29.44 ? 718 HIS A ND1 1 ATOM 5369 C CD2 . HIS A 1 691 ? 0.562 -42.319 67.309 1.00 27.24 ? 718 HIS A CD2 1 ATOM 5370 C CE1 . HIS A 1 691 ? 0.398 -41.039 69.082 1.00 25.36 ? 718 HIS A CE1 1 ATOM 5371 N NE2 . HIS A 1 691 ? -0.184 -42.026 68.426 1.00 24.35 ? 718 HIS A NE2 1 ATOM 5372 N N . LEU A 1 692 ? 4.100 -42.825 68.773 1.00 22.39 ? 719 LEU A N 1 ATOM 5373 C CA . LEU A 1 692 ? 4.533 -44.034 69.443 1.00 23.83 ? 719 LEU A CA 1 ATOM 5374 C C . LEU A 1 692 ? 3.526 -44.408 70.504 1.00 22.46 ? 719 LEU A C 1 ATOM 5375 O O . LEU A 1 692 ? 3.706 -44.091 71.675 1.00 24.32 ? 719 LEU A O 1 ATOM 5376 C CB . LEU A 1 692 ? 5.902 -43.816 70.083 1.00 24.94 ? 719 LEU A CB 1 ATOM 5377 C CG . LEU A 1 692 ? 6.865 -45.006 70.114 1.00 26.84 ? 719 LEU A CG 1 ATOM 5378 C CD1 . LEU A 1 692 ? 8.209 -44.590 70.694 1.00 24.12 ? 719 LEU A CD1 1 ATOM 5379 C CD2 . LEU A 1 692 ? 6.286 -46.169 70.896 1.00 21.28 ? 719 LEU A CD2 1 ATOM 5380 N N . ASP A 1 693 ? 2.463 -45.084 70.094 1.00 21.58 ? 720 ASP A N 1 ATOM 5381 C CA . ASP A 1 693 ? 1.443 -45.497 71.039 1.00 22.66 ? 720 ASP A CA 1 ATOM 5382 C C . ASP A 1 693 ? 1.767 -46.868 71.601 1.00 28.47 ? 720 ASP A C 1 ATOM 5383 O O . ASP A 1 693 ? 1.362 -47.887 71.040 1.00 32.52 ? 720 ASP A O 1 ATOM 5384 C CB . ASP A 1 693 ? 0.073 -45.519 70.375 1.00 25.12 ? 720 ASP A CB 1 ATOM 5385 C CG . ASP A 1 693 ? -1.050 -45.653 71.373 1.00 26.06 ? 720 ASP A CG 1 ATOM 5386 O OD1 . ASP A 1 693 ? -0.960 -46.517 72.271 1.00 20.54 ? 720 ASP A OD1 1 ATOM 5387 O OD2 . ASP A 1 693 ? -2.024 -44.879 71.263 1.00 36.53 1 720 ASP A OD2 1 ATOM 5388 N N . ILE A 1 694 ? 2.494 -46.886 72.713 1.00 27.37 ? 721 ILE A N 1 ATOM 5389 C CA . ILE A 1 694 ? 2.788 -48.129 73.411 1.00 25.60 ? 721 ILE A CA 1 ATOM 5390 C C . ILE A 1 694 ? 1.921 -48.263 74.645 1.00 24.80 ? 721 ILE A C 1 ATOM 5391 O O . ILE A 1 694 ? 2.361 -48.796 75.658 1.00 30.40 ? 721 ILE A O 1 ATOM 5392 C CB . ILE A 1 694 ? 4.258 -48.213 73.848 1.00 25.19 ? 721 ILE A CB 1 ATOM 5393 C CG1 . ILE A 1 694 ? 4.811 -46.813 74.110 1.00 25.04 ? 721 ILE A CG1 1 ATOM 5394 C CG2 . ILE A 1 694 ? 5.080 -48.936 72.799 1.00 30.90 ? 721 ILE A CG2 1 ATOM 5395 C CD1 . ILE A 1 694 ? 6.267 -46.791 74.498 1.00 21.34 ? 721 ILE A CD1 1 ATOM 5396 N N . SER A 1 695 ? 0.692 -47.770 74.564 1.00 26.37 ? 722 SER A N 1 ATOM 5397 C CA . SER A 1 695 ? -0.245 -47.940 75.664 1.00 31.20 ? 722 SER A CA 1 ATOM 5398 C C . SER A 1 695 ? -0.585 -49.420 75.824 1.00 31.29 ? 722 SER A C 1 ATOM 5399 O O . SER A 1 695 ? -0.483 -50.194 74.873 1.00 32.38 ? 722 SER A O 1 ATOM 5400 C CB . SER A 1 695 ? -1.516 -47.107 75.445 1.00 30.19 ? 722 SER A CB 1 ATOM 5401 O OG . SER A 1 695 ? -2.310 -47.624 74.391 1.00 27.11 ? 722 SER A OG 1 ATOM 5402 N N . TRP A 1 696 ? -0.962 -49.804 77.039 1.00 32.69 ? 723 TRP A N 1 ATOM 5403 C CA . TRP A 1 696 ? -1.402 -51.164 77.338 1.00 33.82 ? 723 TRP A CA 1 ATOM 5404 C C . TRP A 1 696 ? -0.428 -52.247 76.880 1.00 37.80 ? 723 TRP A C 1 ATOM 5405 O O . TRP A 1 696 ? -0.747 -53.066 76.018 1.00 38.73 ? 723 TRP A O 1 ATOM 5406 C CB . TRP A 1 696 ? -2.807 -51.399 76.784 1.00 30.95 ? 723 TRP A CB 1 ATOM 5407 C CG . TRP A 1 696 ? -3.782 -50.423 77.353 1.00 34.63 ? 723 TRP A CG 1 ATOM 5408 C CD1 . TRP A 1 696 ? -4.180 -49.242 76.799 1.00 32.77 ? 723 TRP A CD1 1 ATOM 5409 C CD2 . TRP A 1 696 ? -4.454 -50.523 78.613 1.00 38.37 ? 723 TRP A CD2 1 ATOM 5410 N NE1 . TRP A 1 696 ? -5.072 -48.608 77.629 1.00 32.36 ? 723 TRP A NE1 1 ATOM 5411 C CE2 . TRP A 1 696 ? -5.256 -49.374 78.750 1.00 33.77 ? 723 TRP A CE2 1 ATOM 5412 C CE3 . TRP A 1 696 ? -4.460 -51.477 79.637 1.00 40.43 ? 723 TRP A CE3 1 ATOM 5413 C CZ2 . TRP A 1 696 ? -6.057 -49.154 79.867 1.00 38.97 ? 723 TRP A CZ2 1 ATOM 5414 C CZ3 . TRP A 1 696 ? -5.255 -51.257 80.746 1.00 35.65 ? 723 TRP A CZ3 1 ATOM 5415 C CH2 . TRP A 1 696 ? -6.043 -50.105 80.851 1.00 41.31 ? 723 TRP A CH2 1 ATOM 5416 N N . ASN A 1 697 ? 0.764 -52.230 77.468 1.00 38.58 ? 724 ASN A N 1 ATOM 5417 C CA . ASN A 1 697 ? 1.766 -53.264 77.239 1.00 43.13 ? 724 ASN A CA 1 ATOM 5418 C C . ASN A 1 697 ? 2.331 -53.826 78.545 1.00 49.17 ? 724 ASN A C 1 ATOM 5419 O O . ASN A 1 697 ? 1.737 -53.656 79.610 1.00 52.41 ? 724 ASN A O 1 ATOM 5420 C CB . ASN A 1 697 ? 2.888 -52.746 76.338 1.00 41.20 ? 724 ASN A CB 1 ATOM 5421 C CG . ASN A 1 697 ? 2.544 -52.854 74.864 1.00 44.18 ? 724 ASN A CG 1 ATOM 5422 O OD1 . ASN A 1 697 ? 3.017 -53.755 74.168 1.00 39.97 ? 724 ASN A OD1 1 ATOM 5423 N ND2 . ASN A 1 697 ? 1.702 -51.942 74.384 1.00 40.54 ? 724 ASN A ND2 1 ATOM 5424 N N . HIS A 1 698 ? 3.474 -54.498 78.456 1.00 50.69 ? 725 HIS A N 1 ATOM 5425 C CA . HIS A 1 698 ? 4.073 -55.143 79.619 1.00 50.01 ? 725 HIS A CA 1 ATOM 5426 C C . HIS A 1 698 ? 5.255 -54.344 80.153 1.00 49.76 ? 725 HIS A C 1 ATOM 5427 O O . HIS A 1 698 ? 5.945 -54.789 81.072 1.00 58.72 ? 725 HIS A O 1 ATOM 5428 C CB . HIS A 1 698 ? 4.527 -56.561 79.262 1.00 53.32 ? 725 HIS A CB 1 ATOM 5429 C CG . HIS A 1 698 ? 3.401 -57.497 78.948 1.00 54.45 ? 725 HIS A CG 1 ATOM 5430 N ND1 . HIS A 1 698 ? 2.077 -57.128 79.044 1.00 52.31 ? 725 HIS A ND1 1 ATOM 5431 C CD2 . HIS A 1 698 ? 3.403 -58.789 78.545 1.00 55.72 ? 725 HIS A CD2 1 ATOM 5432 C CE1 . HIS A 1 698 ? 1.311 -58.151 78.712 1.00 51.81 ? 725 HIS A CE1 1 ATOM 5433 N NE2 . HIS A 1 698 ? 2.091 -59.172 78.406 1.00 59.86 ? 725 HIS A NE2 1 ATOM 5434 N N . LEU A 1 699 ? 5.488 -53.171 79.570 1.00 44.71 ? 726 LEU A N 1 ATOM 5435 C CA . LEU A 1 699 ? 6.626 -52.335 79.941 1.00 41.36 ? 726 LEU A CA 1 ATOM 5436 C C . LEU A 1 699 ? 6.563 -51.957 81.411 1.00 45.45 ? 726 LEU A C 1 ATOM 5437 O O . LEU A 1 699 ? 5.521 -51.513 81.897 1.00 45.42 ? 726 LEU A O 1 ATOM 5438 C CB . LEU A 1 699 ? 6.650 -51.064 79.094 1.00 34.27 ? 726 LEU A CB 1 ATOM 5439 C CG . LEU A 1 699 ? 6.562 -51.249 77.582 1.00 31.55 ? 726 LEU A CG 1 ATOM 5440 C CD1 . LEU A 1 699 ? 6.420 -49.909 76.894 1.00 29.09 ? 726 LEU A CD1 1 ATOM 5441 C CD2 . LEU A 1 699 ? 7.785 -51.974 77.075 1.00 37.11 ? 726 LEU A CD2 1 ATOM 5442 N N . GLN A 1 700 ? 7.672 -52.143 82.121 1.00 36.65 ? 727 GLN A N 1 ATOM 5443 C CA . GLN A 1 700 ? 7.741 -51.730 83.515 1.00 33.98 ? 727 GLN A CA 1 ATOM 5444 C C . GLN A 1 700 ? 8.660 -50.530 83.653 1.00 31.09 ? 727 GLN A C 1 ATOM 5445 O O . GLN A 1 700 ? 8.500 -49.712 84.557 1.00 30.73 ? 727 GLN A O 1 ATOM 5446 C CB . GLN A 1 700 ? 8.215 -52.878 84.408 1.00 39.72 ? 727 GLN A CB 1 ATOM 5447 C CG . GLN A 1 700 ? 7.263 -54.068 84.445 1.00 45.44 ? 727 GLN A CG 1 ATOM 5448 C CD . GLN A 1 700 ? 7.651 -55.110 85.479 1.00 47.05 ? 727 GLN A CD 1 ATOM 5449 O OE1 . GLN A 1 700 ? 8.711 -55.023 86.103 1.00 48.45 ? 727 GLN A OE1 1 ATOM 5450 N NE2 . GLN A 1 700 ? 6.789 -56.104 85.666 1.00 39.59 ? 727 GLN A NE2 1 ATOM 5451 N N . MET A 1 701 ? 9.612 -50.422 82.732 1.00 32.80 ? 728 MET A N 1 ATOM 5452 C CA . MET A 1 701 ? 10.621 -49.372 82.782 1.00 31.39 ? 728 MET A CA 1 ATOM 5453 C C . MET A 1 701 ? 11.024 -48.935 81.381 1.00 31.80 ? 728 MET A C 1 ATOM 5454 O O . MET A 1 701 ? 11.057 -49.744 80.453 1.00 34.77 ? 728 MET A O 1 ATOM 5455 C CB . MET A 1 701 ? 11.848 -49.868 83.554 1.00 36.28 ? 728 MET A CB 1 ATOM 5456 C CG . MET A 1 701 ? 13.023 -48.896 83.629 1.00 37.40 ? 728 MET A CG 1 ATOM 5457 S SD . MET A 1 701 ? 14.159 -49.019 82.227 1.00 48.41 ? 728 MET A SD 1 ATOM 5458 C CE . MET A 1 701 ? 14.141 -50.788 81.924 1.00 37.30 ? 728 MET A CE 1 ATOM 5459 N N . LEU A 1 702 ? 11.328 -47.650 81.236 1.00 28.56 ? 729 LEU A N 1 ATOM 5460 C CA . LEU A 1 702 ? 11.845 -47.113 79.987 1.00 29.43 ? 729 LEU A CA 1 ATOM 5461 C C . LEU A 1 702 ? 13.189 -46.443 80.240 1.00 33.21 ? 729 LEU A C 1 ATOM 5462 O O . LEU A 1 702 ? 13.283 -45.536 81.064 1.00 40.46 ? 729 LEU A O 1 ATOM 5463 C CB . LEU A 1 702 ? 10.863 -46.103 79.394 1.00 28.07 ? 729 LEU A CB 1 ATOM 5464 C CG . LEU A 1 702 ? 9.955 -46.587 78.260 1.00 29.99 ? 729 LEU A CG 1 ATOM 5465 C CD1 . LEU A 1 702 ? 9.190 -47.836 78.655 1.00 28.36 ? 729 LEU A CD1 1 ATOM 5466 C CD2 . LEU A 1 702 ? 8.995 -45.490 77.837 1.00 25.80 ? 729 LEU A CD2 1 ATOM 5467 N N . ASN A 1 703 ? 14.226 -46.893 79.539 1.00 33.04 ? 730 ASN A N 1 ATOM 5468 C CA . ASN A 1 703 ? 15.564 -46.334 79.711 1.00 43.13 ? 730 ASN A CA 1 ATOM 5469 C C . ASN A 1 703 ? 15.615 -44.855 79.336 1.00 44.60 ? 730 ASN A C 1 ATOM 5470 O O . ASN A 1 703 ? 14.760 -44.364 78.602 1.00 42.65 ? 730 ASN A O 1 ATOM 5471 C CB . ASN A 1 703 ? 16.594 -47.122 78.894 1.00 55.85 ? 730 ASN A CB 1 ATOM 5472 C CG . ASN A 1 703 ? 18.030 -46.867 79.349 1.00 58.00 ? 730 ASN A CG 1 ATOM 5473 O OD1 . ASN A 1 703 ? 18.646 -45.865 78.979 1.00 49.40 ? 730 ASN A OD1 1 ATOM 5474 N ND2 . ASN A 1 703 ? 18.570 -47.784 80.149 1.00 52.38 ? 730 ASN A ND2 1 ATOM 5475 N N . ALA A 1 704 ? 16.623 -44.152 79.844 1.00 50.85 ? 731 ALA A N 1 ATOM 5476 C CA . ALA A 1 704 ? 16.754 -42.713 79.632 1.00 48.45 ? 731 ALA A CA 1 ATOM 5477 C C . ALA A 1 704 ? 17.120 -42.343 78.192 1.00 42.45 ? 731 ALA A C 1 ATOM 5478 O O . ALA A 1 704 ? 17.004 -41.184 77.790 1.00 37.18 ? 731 ALA A O 1 ATOM 5479 C CB . ALA A 1 704 ? 17.770 -42.128 80.607 1.00 48.89 ? 731 ALA A CB 1 ATOM 5480 N N . THR A 1 705 ? 17.565 -43.328 77.421 1.00 40.26 ? 732 THR A N 1 ATOM 5481 C CA . THR A 1 705 ? 17.948 -43.082 76.037 1.00 40.65 ? 732 THR A CA 1 ATOM 5482 C C . THR A 1 705 ? 16.708 -42.953 75.157 1.00 38.42 ? 732 THR A C 1 ATOM 5483 O O . THR A 1 705 ? 16.694 -42.194 74.187 1.00 34.28 ? 732 THR A O 1 ATOM 5484 C CB . THR A 1 705 ? 18.880 -44.190 75.506 1.00 41.82 ? 732 THR A CB 1 ATOM 5485 O OG1 . THR A 1 705 ? 19.184 -43.942 74.127 1.00 42.06 ? 732 THR A OG1 1 ATOM 5486 C CG2 . THR A 1 705 ? 18.235 -45.566 75.655 1.00 40.16 ? 732 THR A CG2 1 ATOM 5487 N N . VAL A 1 706 ? 15.668 -43.697 75.518 1.00 37.65 ? 733 VAL A N 1 ATOM 5488 C CA . VAL A 1 706 ? 14.375 -43.616 74.855 1.00 34.87 ? 733 VAL A CA 1 ATOM 5489 C C . VAL A 1 706 ? 13.765 -42.221 75.016 1.00 33.73 ? 733 VAL A C 1 ATOM 5490 O O . VAL A 1 706 ? 13.211 -41.664 74.068 1.00 36.91 ? 733 VAL A O 1 ATOM 5491 C CB . VAL A 1 706 ? 13.411 -44.707 75.397 1.00 31.59 ? 733 VAL A CB 1 ATOM 5492 C CG1 . VAL A 1 706 ? 11.990 -44.189 75.512 1.00 26.69 ? 733 VAL A CG1 1 ATOM 5493 C CG2 . VAL A 1 706 ? 13.466 -45.950 74.525 1.00 31.69 ? 733 VAL A CG2 1 ATOM 5494 N N . LEU A 1 707 ? 13.893 -41.649 76.208 1.00 31.64 ? 734 LEU A N 1 ATOM 5495 C CA . LEU A 1 707 ? 13.285 -40.353 76.500 1.00 31.95 ? 734 LEU A CA 1 ATOM 5496 C C . LEU A 1 707 ? 13.936 -39.207 75.723 1.00 33.74 ? 734 LEU A C 1 ATOM 5497 O O . LEU A 1 707 ? 13.285 -38.212 75.402 1.00 36.84 ? 734 LEU A O 1 ATOM 5498 C CB . LEU A 1 707 ? 13.313 -40.057 78.004 1.00 31.36 ? 734 LEU A CB 1 ATOM 5499 C CG . LEU A 1 707 ? 12.420 -40.879 78.943 1.00 28.37 ? 734 LEU A CG 1 ATOM 5500 C CD1 . LEU A 1 707 ? 11.412 -41.735 78.184 1.00 26.85 ? 734 LEU A CD1 1 ATOM 5501 C CD2 . LEU A 1 707 ? 13.253 -41.735 79.888 1.00 33.10 ? 734 LEU A CD2 1 ATOM 5502 N N . GLY A 1 708 ? 15.221 -39.343 75.428 1.00 32.70 ? 735 GLY A N 1 ATOM 5503 C CA . GLY A 1 708 ? 15.905 -38.343 74.632 1.00 37.94 ? 735 GLY A CA 1 ATOM 5504 C C . GLY A 1 708 ? 15.440 -38.423 73.193 1.00 41.95 ? 735 GLY A C 1 ATOM 5505 O O . GLY A 1 708 ? 15.329 -37.408 72.501 1.00 42.93 ? 735 GLY A O 1 ATOM 5506 N N . PHE A 1 709 ? 15.163 -39.644 72.745 1.00 44.52 ? 736 PHE A N 1 ATOM 5507 C CA . PHE A 1 709 ? 14.680 -39.876 71.389 1.00 41.41 ? 736 PHE A CA 1 ATOM 5508 C C . PHE A 1 709 ? 13.311 -39.245 71.193 1.00 37.02 ? 736 PHE A C 1 ATOM 5509 O O . PHE A 1 709 ? 13.011 -38.696 70.135 1.00 41.73 ? 736 PHE A O 1 ATOM 5510 C CB . PHE A 1 709 ? 14.617 -41.375 71.081 1.00 36.82 ? 736 PHE A CB 1 ATOM 5511 C CG . PHE A 1 709 ? 13.991 -41.693 69.751 1.00 42.24 ? 736 PHE A CG 1 ATOM 5512 C CD1 . PHE A 1 709 ? 14.518 -41.175 68.577 1.00 41.53 ? 736 PHE A CD1 1 ATOM 5513 C CD2 . PHE A 1 709 ? 12.879 -42.513 69.673 1.00 41.60 ? 736 PHE A CD2 1 ATOM 5514 C CE1 . PHE A 1 709 ? 13.944 -41.464 67.355 1.00 32.21 ? 736 PHE A CE1 1 ATOM 5515 C CE2 . PHE A 1 709 ? 12.302 -42.808 68.451 1.00 38.17 ? 736 PHE A CE2 1 ATOM 5516 C CZ . PHE A 1 709 ? 12.836 -42.282 67.293 1.00 35.43 ? 736 PHE A CZ 1 ATOM 5517 N N . LEU A 1 710 ? 12.488 -39.308 72.231 1.00 32.50 ? 737 LEU A N 1 ATOM 5518 C CA . LEU A 1 710 ? 11.136 -38.779 72.155 1.00 31.04 ? 737 LEU A CA 1 ATOM 5519 C C . LEU A 1 710 ? 11.108 -37.253 72.209 1.00 36.14 ? 737 LEU A C 1 ATOM 5520 O O . LEU A 1 710 ? 10.049 -36.654 72.394 1.00 40.22 ? 737 LEU A O 1 ATOM 5521 C CB . LEU A 1 710 ? 10.268 -39.375 73.262 1.00 26.73 ? 737 LEU A CB 1 ATOM 5522 C CG . LEU A 1 710 ? 9.486 -40.649 72.932 1.00 19.49 ? 737 LEU A CG 1 ATOM 5523 C CD1 . LEU A 1 710 ? 10.330 -41.636 72.163 1.00 26.34 ? 737 LEU A CD1 1 ATOM 5524 C CD2 . LEU A 1 710 ? 8.980 -41.287 74.205 1.00 18.66 ? 737 LEU A CD2 1 ATOM 5525 N N . ASN A 1 711 ? 12.268 -36.626 72.037 1.00 38.17 ? 738 ASN A N 1 ATOM 5526 C CA . ASN A 1 711 ? 12.344 -35.173 71.993 1.00 43.23 ? 738 ASN A CA 1 ATOM 5527 C C . ASN A 1 711 ? 12.079 -34.640 70.587 1.00 42.72 ? 738 ASN A C 1 ATOM 5528 O O . ASN A 1 711 ? 12.994 -34.190 69.899 1.00 43.77 ? 738 ASN A O 1 ATOM 5529 C CB . ASN A 1 711 ? 13.699 -34.683 72.507 1.00 42.91 ? 738 ASN A CB 1 ATOM 5530 C CG . ASN A 1 711 ? 13.754 -33.176 72.657 1.00 51.95 ? 738 ASN A CG 1 ATOM 5531 O OD1 . ASN A 1 711 ? 12.722 -32.503 72.639 1.00 56.19 ? 738 ASN A OD1 1 ATOM 5532 N ND2 . ASN A 1 711 ? 14.962 -32.636 72.809 1.00 46.76 ? 738 ASN A ND2 1 ATOM 5533 N N . TRP A 1 716 ? 8.991 -33.070 67.121 1.00 36.45 ? 743 TRP A N 1 ATOM 5534 C CA . TRP A 1 716 ? 7.826 -33.458 67.910 1.00 42.04 ? 743 TRP A CA 1 ATOM 5535 C C . TRP A 1 716 ? 7.604 -34.964 67.898 1.00 40.27 ? 743 TRP A C 1 ATOM 5536 O O . TRP A 1 716 ? 7.819 -35.624 66.884 1.00 41.69 ? 743 TRP A O 1 ATOM 5537 C CB . TRP A 1 716 ? 6.567 -32.759 67.390 1.00 49.97 ? 743 TRP A CB 1 ATOM 5538 C CG . TRP A 1 716 ? 5.286 -33.341 67.932 1.00 44.29 ? 743 TRP A CG 1 ATOM 5539 C CD1 . TRP A 1 716 ? 4.598 -34.416 67.439 1.00 37.81 ? 743 TRP A CD1 1 ATOM 5540 C CD2 . TRP A 1 716 ? 4.542 -32.876 69.066 1.00 43.78 ? 743 TRP A CD2 1 ATOM 5541 N NE1 . TRP A 1 716 ? 3.480 -34.650 68.199 1.00 47.88 ? 743 TRP A NE1 1 ATOM 5542 C CE2 . TRP A 1 716 ? 3.419 -33.717 69.202 1.00 50.89 ? 743 TRP A CE2 1 ATOM 5543 C CE3 . TRP A 1 716 ? 4.715 -31.829 69.976 1.00 37.38 ? 743 TRP A CE3 1 ATOM 5544 C CZ2 . TRP A 1 716 ? 2.472 -33.542 70.213 1.00 42.60 ? 743 TRP A CZ2 1 ATOM 5545 C CZ3 . TRP A 1 716 ? 3.778 -31.659 70.978 1.00 32.82 ? 743 TRP A CZ3 1 ATOM 5546 C CH2 . TRP A 1 716 ? 2.671 -32.511 71.089 1.00 36.77 ? 743 TRP A CH2 1 ATOM 5547 N N . ARG A 1 717 ? 7.172 -35.504 69.034 1.00 36.12 ? 744 ARG A N 1 ATOM 5548 C CA . ARG A 1 717 ? 6.754 -36.898 69.111 1.00 35.94 ? 744 ARG A CA 1 ATOM 5549 C C . ARG A 1 717 ? 5.552 -37.041 70.050 1.00 39.71 ? 744 ARG A C 1 ATOM 5550 O O . ARG A 1 717 ? 5.700 -36.897 71.264 1.00 41.27 ? 744 ARG A O 1 ATOM 5551 C CB . ARG A 1 717 ? 7.893 -37.786 69.623 1.00 23.53 ? 744 ARG A CB 1 ATOM 5552 C CG . ARG A 1 717 ? 9.294 -37.264 69.374 1.00 33.01 ? 744 ARG A CG 1 ATOM 5553 C CD . ARG A 1 717 ? 9.847 -37.706 68.031 1.00 41.61 ? 744 ARG A CD 1 ATOM 5554 N NE . ARG A 1 717 ? 11.307 -37.619 67.997 1.00 43.61 ? 744 ARG A NE 1 ATOM 5555 C CZ . ARG A 1 717 ? 12.064 -38.010 66.974 1.00 42.51 ? 744 ARG A CZ 1 ATOM 5556 N NH1 . ARG A 1 717 ? 11.506 -38.514 65.879 1.00 44.16 1 744 ARG A NH1 1 ATOM 5557 N NH2 . ARG A 1 717 ? 13.383 -37.895 67.044 1.00 39.94 ? 744 ARG A NH2 1 ATOM 5558 N N . SER A 1 718 ? 4.368 -37.319 69.506 1.00 28.14 ? 745 SER A N 1 ATOM 5559 C CA . SER A 1 718 ? 3.231 -37.653 70.358 1.00 21.16 ? 745 SER A CA 1 ATOM 5560 C C . SER A 1 718 ? 3.446 -39.064 70.890 1.00 22.29 ? 745 SER A C 1 ATOM 5561 O O . SER A 1 718 ? 3.827 -39.960 70.137 1.00 22.52 ? 745 SER A O 1 ATOM 5562 C CB . SER A 1 718 ? 1.910 -37.560 69.592 1.00 23.61 ? 745 SER A CB 1 ATOM 5563 O OG . SER A 1 718 ? 0.795 -37.525 70.473 1.00 18.85 ? 745 SER A OG 1 ATOM 5564 N N . VAL A 1 719 ? 3.234 -39.250 72.192 1.00 22.89 ? 746 VAL A N 1 ATOM 5565 C CA . VAL A 1 719 ? 3.484 -40.535 72.847 1.00 18.22 ? 746 VAL A CA 1 ATOM 5566 C C . VAL A 1 719 ? 2.311 -40.972 73.721 1.00 15.44 ? 746 VAL A C 1 ATOM 5567 O O . VAL A 1 719 ? 1.658 -40.142 74.344 1.00 17.49 ? 746 VAL A O 1 ATOM 5568 C CB . VAL A 1 719 ? 4.714 -40.463 73.769 1.00 17.52 ? 746 VAL A CB 1 ATOM 5569 C CG1 . VAL A 1 719 ? 5.323 -41.841 73.937 1.00 18.79 ? 746 VAL A CG1 1 ATOM 5570 C CG2 . VAL A 1 719 ? 5.743 -39.483 73.233 1.00 19.43 ? 746 VAL A CG2 1 ATOM 5571 N N . LYS A 1 720 ? 2.054 -42.275 73.775 1.00 15.02 ? 747 LYS A N 1 ATOM 5572 C CA . LYS A 1 720 ? 1.050 -42.829 74.684 1.00 20.03 ? 747 LYS A CA 1 ATOM 5573 C C . LYS A 1 720 ? 1.716 -43.837 75.615 1.00 22.93 ? 747 LYS A C 1 ATOM 5574 O O . LYS A 1 720 ? 2.506 -44.666 75.165 1.00 22.96 ? 747 LYS A O 1 ATOM 5575 C CB . LYS A 1 720 ? -0.076 -43.510 73.907 1.00 21.82 ? 747 LYS A CB 1 ATOM 5576 C CG . LYS A 1 720 ? -0.947 -42.571 73.088 1.00 21.80 ? 747 LYS A CG 1 ATOM 5577 C CD . LYS A 1 720 ? -2.007 -41.904 73.948 1.00 23.64 ? 747 LYS A CD 1 ATOM 5578 C CE . LYS A 1 720 ? -3.264 -41.596 73.139 1.00 36.17 ? 747 LYS A CE 1 ATOM 5579 N NZ . LYS A 1 720 ? -3.923 -42.826 72.581 1.00 24.67 1 747 LYS A NZ 1 ATOM 5580 N N . LEU A 1 721 ? 1.397 -43.776 76.906 1.00 23.21 ? 748 LEU A N 1 ATOM 5581 C CA . LEU A 1 721 ? 2.134 -44.559 77.898 1.00 20.77 ? 748 LEU A CA 1 ATOM 5582 C C . LEU A 1 721 ? 1.292 -45.242 78.979 1.00 23.33 ? 748 LEU A C 1 ATOM 5583 O O . LEU A 1 721 ? 1.815 -46.039 79.751 1.00 28.63 ? 748 LEU A O 1 ATOM 5584 C CB . LEU A 1 721 ? 3.186 -43.679 78.573 1.00 20.13 ? 748 LEU A CB 1 ATOM 5585 C CG . LEU A 1 721 ? 4.297 -43.115 77.690 1.00 20.50 ? 748 LEU A CG 1 ATOM 5586 C CD1 . LEU A 1 721 ? 5.157 -42.143 78.478 1.00 18.68 ? 748 LEU A CD1 1 ATOM 5587 C CD2 . LEU A 1 721 ? 5.138 -44.239 77.116 1.00 21.18 ? 748 LEU A CD2 1 ATOM 5588 N N . SER A 1 722 ? 0.002 -44.938 79.048 1.00 24.73 ? 749 SER A N 1 ATOM 5589 C CA . SER A 1 722 ? -0.817 -45.455 80.142 1.00 28.61 ? 749 SER A CA 1 ATOM 5590 C C . SER A 1 722 ? -1.010 -46.962 80.035 1.00 29.80 ? 749 SER A C 1 ATOM 5591 O O . SER A 1 722 ? -0.615 -47.576 79.048 1.00 27.80 ? 749 SER A O 1 ATOM 5592 C CB . SER A 1 722 ? -2.178 -44.758 80.186 1.00 29.15 ? 749 SER A CB 1 ATOM 5593 O OG . SER A 1 722 ? -2.988 -45.158 79.097 1.00 28.18 ? 749 SER A OG 1 ATOM 5594 N N . GLY A 1 723 ? -1.608 -47.549 81.066 1.00 35.98 ? 750 GLY A N 1 ATOM 5595 C CA . GLY A 1 723 ? -1.968 -48.955 81.049 1.00 32.29 ? 750 GLY A CA 1 ATOM 5596 C C . GLY A 1 723 ? -0.792 -49.909 81.098 1.00 36.06 ? 750 GLY A C 1 ATOM 5597 O O . GLY A 1 723 ? -0.913 -51.066 80.698 1.00 34.45 ? 750 GLY A O 1 ATOM 5598 N N . ASN A 1 724 ? 0.350 -49.430 81.582 1.00 37.80 ? 751 ASN A N 1 ATOM 5599 C CA . ASN A 1 724 ? 1.522 -50.284 81.746 1.00 35.24 ? 751 ASN A CA 1 ATOM 5600 C C . ASN A 1 724 ? 1.913 -50.455 83.206 1.00 43.51 ? 751 ASN A C 1 ATOM 5601 O O . ASN A 1 724 ? 1.723 -49.542 84.014 1.00 42.13 ? 751 ASN A O 1 ATOM 5602 C CB . ASN A 1 724 ? 2.705 -49.746 80.946 1.00 34.82 ? 751 ASN A CB 1 ATOM 5603 C CG . ASN A 1 724 ? 2.476 -49.825 79.458 1.00 40.55 ? 751 ASN A CG 1 ATOM 5604 O OD1 . ASN A 1 724 ? 1.353 -49.655 78.984 1.00 41.36 ? 751 ASN A OD1 1 ATOM 5605 N ND2 . ASN A 1 724 ? 3.538 -50.097 78.707 1.00 40.61 ? 751 ASN A ND2 1 ATOM 5606 N N . PRO A 1 725 ? 2.461 -51.634 83.550 1.00 45.41 ? 752 PRO A N 1 ATOM 5607 C CA . PRO A 1 725 ? 2.860 -51.934 84.928 1.00 41.48 ? 752 PRO A CA 1 ATOM 5608 C C . PRO A 1 725 ? 4.125 -51.176 85.310 1.00 45.00 ? 752 PRO A C 1 ATOM 5609 O O . PRO A 1 725 ? 5.193 -51.777 85.417 1.00 52.45 ? 752 PRO A O 1 ATOM 5610 C CB . PRO A 1 725 ? 3.145 -53.434 84.878 1.00 40.25 ? 752 PRO A CB 1 ATOM 5611 C CG . PRO A 1 725 ? 3.574 -53.677 83.469 1.00 39.79 ? 752 PRO A CG 1 ATOM 5612 C CD . PRO A 1 725 ? 2.736 -52.759 82.638 1.00 40.05 ? 752 PRO A CD 1 ATOM 5613 N N . TRP A 1 726 ? 4.005 -49.870 85.518 1.00 39.44 ? 753 TRP A N 1 ATOM 5614 C CA . TRP A 1 726 ? 5.174 -49.047 85.788 1.00 35.25 ? 753 TRP A CA 1 ATOM 5615 C C . TRP A 1 726 ? 5.738 -49.250 87.188 1.00 47.50 ? 753 TRP A C 1 ATOM 5616 O O . TRP A 1 726 ? 5.115 -48.886 88.189 1.00 44.17 ? 753 TRP A O 1 ATOM 5617 C CB . TRP A 1 726 ? 4.866 -47.574 85.551 1.00 30.93 ? 753 TRP A CB 1 ATOM 5618 C CG . TRP A 1 726 ? 4.462 -47.295 84.150 1.00 36.16 ? 753 TRP A CG 1 ATOM 5619 C CD1 . TRP A 1 726 ? 3.244 -46.863 83.717 1.00 39.02 ? 753 TRP A CD1 1 ATOM 5620 C CD2 . TRP A 1 726 ? 5.271 -47.452 82.983 1.00 32.19 ? 753 TRP A CD2 1 ATOM 5621 N NE1 . TRP A 1 726 ? 3.249 -46.729 82.351 1.00 30.68 ? 753 TRP A NE1 1 ATOM 5622 C CE2 . TRP A 1 726 ? 4.484 -47.085 81.877 1.00 29.46 ? 753 TRP A CE2 1 ATOM 5623 C CE3 . TRP A 1 726 ? 6.589 -47.859 82.766 1.00 34.88 ? 753 TRP A CE3 1 ATOM 5624 C CZ2 . TRP A 1 726 ? 4.968 -47.115 80.575 1.00 29.71 ? 753 TRP A CZ2 1 ATOM 5625 C CZ3 . TRP A 1 726 ? 7.067 -47.888 81.472 1.00 32.88 ? 753 TRP A CZ3 1 ATOM 5626 C CH2 . TRP A 1 726 ? 6.259 -47.519 80.394 1.00 29.19 ? 753 TRP A CH2 1 ATOM 5627 N N . MET A 1 727 ? 6.927 -49.843 87.241 1.00 48.45 ? 754 MET A N 1 ATOM 5628 C CA . MET A 1 727 ? 7.677 -49.954 88.479 1.00 44.41 ? 754 MET A CA 1 ATOM 5629 C C . MET A 1 727 ? 8.327 -48.607 88.769 1.00 43.09 ? 754 MET A C 1 ATOM 5630 O O . MET A 1 727 ? 9.326 -48.242 88.146 1.00 37.36 ? 754 MET A O 1 ATOM 5631 C CB . MET A 1 727 ? 8.742 -51.042 88.356 1.00 51.74 ? 754 MET A CB 1 ATOM 5632 C CG . MET A 1 727 ? 9.582 -51.242 89.607 1.00 61.95 ? 754 MET A CG 1 ATOM 5633 S SD . MET A 1 727 ? 10.962 -52.365 89.327 1.00 74.15 ? 754 MET A SD 1 ATOM 5634 C CE . MET A 1 727 ? 11.745 -52.355 90.937 1.00 67.91 ? 754 MET A CE 1 ATOM 5635 N N . CYS A 1 728 ? 7.744 -47.870 89.711 1.00 47.29 ? 755 CYS A N 1 ATOM 5636 C CA . CYS A 1 728 ? 8.210 -46.529 90.052 1.00 49.79 ? 755 CYS A CA 1 ATOM 5637 C C . CYS A 1 728 ? 9.146 -46.520 91.265 1.00 48.79 ? 755 CYS A C 1 ATOM 5638 O O . CYS A 1 728 ? 8.701 -46.509 92.414 1.00 45.93 ? 755 CYS A O 1 ATOM 5639 C CB . CYS A 1 728 ? 7.020 -45.606 90.321 1.00 50.08 ? 755 CYS A CB 1 ATOM 5640 S SG . CYS A 1 728 ? 5.664 -45.767 89.150 1.00 26.48 ? 755 CYS A SG 1 ATOM 5641 N N . ASP A 1 729 ? 10.444 -46.523 90.998 1.00 44.59 ? 756 ASP A N 1 ATOM 5642 C CA . ASP A 1 729 ? 11.442 -46.422 92.048 1.00 40.86 ? 756 ASP A CA 1 ATOM 5643 C C . ASP A 1 729 ? 12.464 -45.386 91.611 1.00 45.02 ? 756 ASP A C 1 ATOM 5644 O O . ASP A 1 729 ? 12.121 -44.421 90.930 1.00 48.82 ? 756 ASP A O 1 ATOM 5645 C CB . ASP A 1 729 ? 12.116 -47.769 92.266 1.00 37.98 ? 756 ASP A CB 1 ATOM 5646 C CG . ASP A 1 729 ? 12.700 -48.327 90.992 1.00 44.28 ? 756 ASP A CG 1 ATOM 5647 O OD1 . ASP A 1 729 ? 13.800 -47.882 90.603 1.00 42.10 1 756 ASP A OD1 1 ATOM 5648 O OD2 . ASP A 1 729 ? 12.053 -49.197 90.373 1.00 46.04 ? 756 ASP A OD2 1 ATOM 5649 N N . CYS A 1 730 ? 13.722 -45.582 91.983 1.00 44.54 ? 757 CYS A N 1 ATOM 5650 C CA . CYS A 1 730 ? 14.751 -44.618 91.615 1.00 46.99 ? 757 CYS A CA 1 ATOM 5651 C C . CYS A 1 730 ? 15.217 -44.759 90.167 1.00 41.69 ? 757 CYS A C 1 ATOM 5652 O O . CYS A 1 730 ? 15.764 -43.815 89.598 1.00 42.90 ? 757 CYS A O 1 ATOM 5653 C CB . CYS A 1 730 ? 15.937 -44.672 92.583 1.00 48.80 ? 757 CYS A CB 1 ATOM 5654 S SG . CYS A 1 730 ? 15.878 -43.400 93.873 1.00 50.40 ? 757 CYS A SG 1 ATOM 5655 N N . THR A 1 731 ? 14.999 -45.925 89.567 1.00 37.99 ? 758 THR A N 1 ATOM 5656 C CA . THR A 1 731 ? 15.404 -46.121 88.179 1.00 43.30 ? 758 THR A CA 1 ATOM 5657 C C . THR A 1 731 ? 14.337 -45.606 87.222 1.00 43.36 ? 758 THR A C 1 ATOM 5658 O O . THR A 1 731 ? 14.574 -45.476 86.021 1.00 43.60 ? 758 THR A O 1 ATOM 5659 C CB . THR A 1 731 ? 15.720 -47.594 87.854 1.00 48.11 ? 758 THR A CB 1 ATOM 5660 O OG1 . THR A 1 731 ? 16.413 -47.666 86.600 1.00 45.09 ? 758 THR A OG1 1 ATOM 5661 C CG2 . THR A 1 731 ? 14.441 -48.417 87.774 1.00 47.20 ? 758 THR A CG2 1 ATOM 5662 N N . ALA A 1 732 ? 13.160 -45.317 87.769 1.00 44.84 ? 759 ALA A N 1 ATOM 5663 C CA . ALA A 1 732 ? 12.063 -44.758 86.991 1.00 41.12 ? 759 ALA A CA 1 ATOM 5664 C C . ALA A 1 732 ? 12.119 -43.237 87.042 1.00 34.28 ? 759 ALA A C 1 ATOM 5665 O O . ALA A 1 732 ? 11.436 -42.557 86.275 1.00 32.45 ? 759 ALA A O 1 ATOM 5666 C CB . ALA A 1 732 ? 10.725 -45.261 87.518 1.00 39.47 ? 759 ALA A CB 1 ATOM 5667 N N . LYS A 1 733 ? 12.944 -42.718 87.951 1.00 30.75 ? 760 LYS A N 1 ATOM 5668 C CA . LYS A 1 733 ? 13.120 -41.275 88.124 1.00 30.11 ? 760 LYS A CA 1 ATOM 5669 C C . LYS A 1 733 ? 13.285 -40.463 86.827 1.00 28.09 ? 760 LYS A C 1 ATOM 5670 O O . LYS A 1 733 ? 12.716 -39.375 86.721 1.00 27.52 ? 760 LYS A O 1 ATOM 5671 C CB . LYS A 1 733 ? 14.264 -40.971 89.105 1.00 33.07 ? 760 LYS A CB 1 ATOM 5672 C CG . LYS A 1 733 ? 14.518 -39.479 89.328 1.00 33.09 ? 760 LYS A CG 1 ATOM 5673 C CD . LYS A 1 733 ? 15.555 -39.238 90.418 1.00 43.26 ? 760 LYS A CD 1 ATOM 5674 C CE . LYS A 1 733 ? 15.783 -37.747 90.656 1.00 51.92 ? 760 LYS A CE 1 ATOM 5675 N NZ . LYS A 1 733 ? 16.730 -37.489 91.786 1.00 57.73 1 760 LYS A NZ 1 ATOM 5676 N N . PRO A 1 734 ? 14.058 -40.974 85.843 1.00 25.02 ? 761 PRO A N 1 ATOM 5677 C CA . PRO A 1 734 ? 14.122 -40.206 84.596 1.00 26.23 ? 761 PRO A CA 1 ATOM 5678 C C . PRO A 1 734 ? 12.749 -40.086 83.945 1.00 27.77 ? 761 PRO A C 1 ATOM 5679 O O . PRO A 1 734 ? 12.358 -38.993 83.524 1.00 23.29 ? 761 PRO A O 1 ATOM 5680 C CB . PRO A 1 734 ? 15.040 -41.055 83.713 1.00 21.94 ? 761 PRO A CB 1 ATOM 5681 C CG . PRO A 1 734 ? 15.874 -41.802 84.651 1.00 19.92 ? 761 PRO A CG 1 ATOM 5682 C CD . PRO A 1 734 ? 14.999 -42.108 85.821 1.00 24.79 ? 761 PRO A CD 1 ATOM 5683 N N . LEU A 1 735 ? 12.029 -41.203 83.880 1.00 28.26 ? 762 LEU A N 1 ATOM 5684 C CA . LEU A 1 735 ? 10.718 -41.238 83.249 1.00 25.33 ? 762 LEU A CA 1 ATOM 5685 C C . LEU A 1 735 ? 9.767 -40.306 83.977 1.00 23.68 ? 762 LEU A C 1 ATOM 5686 O O . LEU A 1 735 ? 8.951 -39.628 83.355 1.00 26.89 ? 762 LEU A O 1 ATOM 5687 C CB . LEU A 1 735 ? 10.158 -42.662 83.243 1.00 27.01 ? 762 LEU A CB 1 ATOM 5688 C CG . LEU A 1 735 ? 8.872 -42.861 82.440 1.00 21.58 ? 762 LEU A CG 1 ATOM 5689 C CD1 . LEU A 1 735 ? 9.144 -42.645 80.963 1.00 15.88 ? 762 LEU A CD1 1 ATOM 5690 C CD2 . LEU A 1 735 ? 8.261 -44.235 82.698 1.00 17.87 ? 762 LEU A CD2 1 ATOM 5691 N N . LEU A 1 736 ? 9.888 -40.266 85.299 1.00 23.19 ? 763 LEU A N 1 ATOM 5692 C CA . LEU A 1 736 ? 9.028 -39.420 86.112 1.00 23.41 ? 763 LEU A CA 1 ATOM 5693 C C . LEU A 1 736 ? 9.303 -37.941 85.854 1.00 23.78 ? 763 LEU A C 1 ATOM 5694 O O . LEU A 1 736 ? 8.419 -37.106 86.003 1.00 28.22 ? 763 LEU A O 1 ATOM 5695 C CB . LEU A 1 736 ? 9.191 -39.746 87.596 1.00 20.83 ? 763 LEU A CB 1 ATOM 5696 C CG . LEU A 1 736 ? 8.041 -39.299 88.498 1.00 21.33 ? 763 LEU A CG 1 ATOM 5697 C CD1 . LEU A 1 736 ? 7.428 -40.490 89.208 1.00 27.19 ? 763 LEU A CD1 1 ATOM 5698 C CD2 . LEU A 1 736 ? 8.517 -38.277 89.503 1.00 27.88 ? 763 LEU A CD2 1 ATOM 5699 N N . LEU A 1 737 ? 10.526 -37.611 85.460 1.00 21.54 ? 764 LEU A N 1 ATOM 5700 C CA . LEU A 1 737 ? 10.825 -36.236 85.088 1.00 22.80 ? 764 LEU A CA 1 ATOM 5701 C C . LEU A 1 737 ? 10.382 -35.953 83.659 1.00 21.32 ? 764 LEU A C 1 ATOM 5702 O O . LEU A 1 737 ? 10.039 -34.818 83.322 1.00 20.63 ? 764 LEU A O 1 ATOM 5703 C CB . LEU A 1 737 ? 12.313 -35.924 85.252 1.00 27.85 ? 764 LEU A CB 1 ATOM 5704 C CG . LEU A 1 737 ? 12.800 -35.552 86.654 1.00 24.18 ? 764 LEU A CG 1 ATOM 5705 C CD1 . LEU A 1 737 ? 14.249 -35.116 86.588 1.00 33.78 ? 764 LEU A CD1 1 ATOM 5706 C CD2 . LEU A 1 737 ? 11.941 -34.460 87.270 1.00 17.53 ? 764 LEU A CD2 1 ATOM 5707 N N . PHE A 1 738 ? 10.399 -36.990 82.825 1.00 23.05 ? 765 PHE A N 1 ATOM 5708 C CA . PHE A 1 738 ? 9.975 -36.862 81.436 1.00 19.86 ? 765 PHE A CA 1 ATOM 5709 C C . PHE A 1 738 ? 8.545 -36.387 81.407 1.00 18.97 ? 765 PHE A C 1 ATOM 5710 O O . PHE A 1 738 ? 8.242 -35.312 80.887 1.00 19.75 ? 765 PHE A O 1 ATOM 5711 C CB . PHE A 1 738 ? 10.080 -38.201 80.708 1.00 17.84 ? 765 PHE A CB 1 ATOM 5712 C CG . PHE A 1 738 ? 9.749 -38.123 79.242 1.00 22.12 ? 765 PHE A CG 1 ATOM 5713 C CD1 . PHE A 1 738 ? 10.336 -37.163 78.434 1.00 24.38 ? 765 PHE A CD1 1 ATOM 5714 C CD2 . PHE A 1 738 ? 8.866 -39.020 78.665 1.00 23.59 ? 765 PHE A CD2 1 ATOM 5715 C CE1 . PHE A 1 738 ? 10.037 -37.095 77.086 1.00 20.12 ? 765 PHE A CE1 1 ATOM 5716 C CE2 . PHE A 1 738 ? 8.565 -38.954 77.316 1.00 15.48 ? 765 PHE A CE2 1 ATOM 5717 C CZ . PHE A 1 738 ? 9.152 -37.991 76.531 1.00 17.37 ? 765 PHE A CZ 1 ATOM 5718 N N . THR A 1 739 ? 7.675 -37.198 81.995 1.00 20.37 ? 766 THR A N 1 ATOM 5719 C CA . THR A 1 739 ? 6.256 -36.901 82.060 1.00 20.04 ? 766 THR A CA 1 ATOM 5720 C C . THR A 1 739 ? 6.019 -35.514 82.643 1.00 17.76 ? 766 THR A C 1 ATOM 5721 O O . THR A 1 739 ? 5.244 -34.727 82.100 1.00 19.00 ? 766 THR A O 1 ATOM 5722 C CB . THR A 1 739 ? 5.515 -37.953 82.905 1.00 17.93 ? 766 THR A CB 1 ATOM 5723 O OG1 . THR A 1 739 ? 5.904 -37.830 84.277 1.00 15.89 ? 766 THR A OG1 1 ATOM 5724 C CG2 . THR A 1 739 ? 5.844 -39.353 82.413 1.00 15.10 ? 766 THR A CG2 1 ATOM 5725 N N . GLN A 1 740 ? 6.719 -35.206 83.727 1.00 14.54 ? 767 GLN A N 1 ATOM 5726 C CA . GLN A 1 740 ? 6.487 -33.961 84.444 1.00 17.88 ? 767 GLN A CA 1 ATOM 5727 C C . GLN A 1 740 ? 6.703 -32.714 83.594 1.00 20.44 ? 767 GLN A C 1 ATOM 5728 O O . GLN A 1 740 ? 6.166 -31.652 83.903 1.00 23.09 ? 767 GLN A O 1 ATOM 5729 C CB . GLN A 1 740 ? 7.337 -33.897 85.712 1.00 20.38 ? 767 GLN A CB 1 ATOM 5730 C CG . GLN A 1 740 ? 6.727 -34.623 86.901 1.00 25.23 ? 767 GLN A CG 1 ATOM 5731 C CD . GLN A 1 740 ? 7.658 -34.663 88.102 1.00 29.18 ? 767 GLN A CD 1 ATOM 5732 O OE1 . GLN A 1 740 ? 8.752 -34.090 88.078 1.00 23.89 ? 767 GLN A OE1 1 ATOM 5733 N NE2 . GLN A 1 740 ? 7.225 -35.337 89.163 1.00 29.39 ? 767 GLN A NE2 1 ATOM 5734 N N . ASP A 1 741 ? 7.475 -32.832 82.521 1.00 20.15 ? 768 ASP A N 1 ATOM 5735 C CA . ASP A 1 741 ? 7.705 -31.670 81.675 1.00 19.79 ? 768 ASP A CA 1 ATOM 5736 C C . ASP A 1 741 ? 7.183 -31.848 80.261 1.00 22.68 ? 768 ASP A C 1 ATOM 5737 O O . ASP A 1 741 ? 6.784 -30.882 79.617 1.00 27.05 ? 768 ASP A O 1 ATOM 5738 C CB . ASP A 1 741 ? 9.180 -31.292 81.638 1.00 19.11 ? 768 ASP A CB 1 ATOM 5739 C CG . ASP A 1 741 ? 9.414 -29.977 80.930 1.00 24.42 ? 768 ASP A CG 1 ATOM 5740 O OD1 . ASP A 1 741 ? 9.301 -28.915 81.588 1.00 17.90 1 768 ASP A OD1 1 ATOM 5741 O OD2 . ASP A 1 741 ? 9.693 -30.007 79.710 1.00 28.51 ? 768 ASP A OD2 1 ATOM 5742 N N . ASN A 1 742 ? 7.186 -33.081 79.775 1.00 20.64 ? 769 ASN A N 1 ATOM 5743 C CA . ASN A 1 742 ? 6.689 -33.344 78.431 1.00 24.46 ? 769 ASN A CA 1 ATOM 5744 C C . ASN A 1 742 ? 5.195 -33.624 78.396 1.00 25.04 ? 769 ASN A C 1 ATOM 5745 O O . ASN A 1 742 ? 4.762 -34.675 77.929 1.00 24.96 ? 769 ASN A O 1 ATOM 5746 C CB . ASN A 1 742 ? 7.475 -34.476 77.781 1.00 22.20 ? 769 ASN A CB 1 ATOM 5747 C CG . ASN A 1 742 ? 8.811 -34.011 77.257 1.00 29.16 ? 769 ASN A CG 1 ATOM 5748 O OD1 . ASN A 1 742 ? 9.096 -34.120 76.063 1.00 32.30 ? 769 ASN A OD1 1 ATOM 5749 N ND2 . ASN A 1 742 ? 9.631 -33.452 78.142 1.00 30.19 ? 769 ASN A ND2 1 ATOM 5750 N N . PHE A 1 743 ? 4.420 -32.658 78.881 1.00 25.34 ? 770 PHE A N 1 ATOM 5751 C CA . PHE A 1 743 ? 2.968 -32.778 79.003 1.00 26.52 ? 770 PHE A CA 1 ATOM 5752 C C . PHE A 1 743 ? 2.237 -32.937 77.673 1.00 29.39 ? 770 PHE A C 1 ATOM 5753 O O . PHE A 1 743 ? 1.367 -33.800 77.539 1.00 29.88 ? 770 PHE A O 1 ATOM 5754 C CB . PHE A 1 743 ? 2.418 -31.566 79.749 1.00 29.47 ? 770 PHE A CB 1 ATOM 5755 C CG . PHE A 1 743 ? 0.956 -31.312 79.514 1.00 31.40 ? 770 PHE A CG 1 ATOM 5756 C CD1 . PHE A 1 743 ? -0.006 -32.168 80.034 1.00 38.61 ? 770 PHE A CD1 1 ATOM 5757 C CD2 . PHE A 1 743 ? 0.541 -30.197 78.800 1.00 26.03 ? 770 PHE A CD2 1 ATOM 5758 C CE1 . PHE A 1 743 ? -1.356 -31.923 79.831 1.00 43.55 ? 770 PHE A CE1 1 ATOM 5759 C CE2 . PHE A 1 743 ? -0.804 -29.946 78.596 1.00 30.86 ? 770 PHE A CE2 1 ATOM 5760 C CZ . PHE A 1 743 ? -1.755 -30.810 79.111 1.00 38.45 ? 770 PHE A CZ 1 ATOM 5761 N N . GLU A 1 744 ? 2.584 -32.092 76.704 1.00 33.39 ? 771 GLU A N 1 ATOM 5762 C CA . GLU A 1 744 ? 1.977 -32.111 75.372 1.00 24.10 ? 771 GLU A CA 1 ATOM 5763 C C . GLU A 1 744 ? 2.098 -33.473 74.705 1.00 24.42 ? 771 GLU A C 1 ATOM 5764 O O . GLU A 1 744 ? 1.108 -34.033 74.235 1.00 25.83 ? 771 GLU A O 1 ATOM 5765 C CB . GLU A 1 744 ? 2.635 -31.059 74.479 1.00 17.41 ? 771 GLU A CB 1 ATOM 5766 C CG . GLU A 1 744 ? 2.431 -29.621 74.933 1.00 21.14 ? 771 GLU A CG 1 ATOM 5767 C CD . GLU A 1 744 ? 3.386 -29.191 76.032 1.00 23.13 ? 771 GLU A CD 1 ATOM 5768 O OE1 . GLU A 1 744 ? 3.648 -29.992 76.953 1.00 26.78 ? 771 GLU A OE1 1 ATOM 5769 O OE2 . GLU A 1 744 ? 3.879 -28.044 75.973 1.00 20.18 1 771 GLU A OE2 1 ATOM 5770 N N . ARG A 1 745 ? 3.320 -33.995 74.679 1.00 24.38 ? 772 ARG A N 1 ATOM 5771 C CA . ARG A 1 745 ? 3.626 -35.255 74.015 1.00 23.49 ? 772 ARG A CA 1 ATOM 5772 C C . ARG A 1 745 ? 2.803 -36.425 74.537 1.00 20.01 ? 772 ARG A C 1 ATOM 5773 O O . ARG A 1 745 ? 2.397 -37.294 73.770 1.00 20.53 ? 772 ARG A O 1 ATOM 5774 C CB . ARG A 1 745 ? 5.112 -35.582 74.158 1.00 22.78 ? 772 ARG A CB 1 ATOM 5775 C CG . ARG A 1 745 ? 6.034 -34.683 73.370 1.00 25.54 ? 772 ARG A CG 1 ATOM 5776 C CD . ARG A 1 745 ? 7.464 -35.143 73.532 1.00 22.99 ? 772 ARG A CD 1 ATOM 5777 N NE . ARG A 1 745 ? 8.345 -34.692 72.459 1.00 30.74 ? 772 ARG A NE 1 ATOM 5778 C CZ . ARG A 1 745 ? 8.431 -33.440 72.020 1.00 36.43 ? 772 ARG A CZ 1 ATOM 5779 N NH1 . ARG A 1 745 ? 7.675 -32.484 72.546 1.00 34.79 1 772 ARG A NH1 1 ATOM 5780 N NH2 . ARG A 1 745 ? 9.275 -33.143 71.041 1.00 38.93 ? 772 ARG A NH2 1 ATOM 5781 N N . ILE A 1 746 ? 2.560 -36.453 75.840 1.00 16.77 ? 773 ILE A N 1 ATOM 5782 C CA . ILE A 1 746 ? 1.889 -37.598 76.437 1.00 18.11 ? 773 ILE A CA 1 ATOM 5783 C C . ILE A 1 746 ? 0.416 -37.308 76.704 1.00 24.09 ? 773 ILE A C 1 ATOM 5784 O O . ILE A 1 746 ? 0.072 -36.518 77.584 1.00 24.77 ? 773 ILE A O 1 ATOM 5785 C CB . ILE A 1 746 ? 2.590 -38.051 77.725 1.00 17.20 ? 773 ILE A CB 1 ATOM 5786 C CG1 . ILE A 1 746 ? 4.079 -38.278 77.460 1.00 16.59 ? 773 ILE A CG1 1 ATOM 5787 C CG2 . ILE A 1 746 ? 1.955 -39.319 78.255 1.00 18.60 ? 773 ILE A CG2 1 ATOM 5788 C CD1 . ILE A 1 746 ? 4.913 -38.376 78.707 1.00 16.10 ? 773 ILE A CD1 1 ATOM 5789 N N . GLY A 1 747 ? -0.451 -37.955 75.932 1.00 23.89 ? 774 GLY A N 1 ATOM 5790 C CA . GLY A 1 747 ? -1.877 -37.720 76.027 1.00 18.63 ? 774 GLY A CA 1 ATOM 5791 C C . GLY A 1 747 ? -2.490 -38.293 77.285 1.00 20.96 ? 774 GLY A C 1 ATOM 5792 O O . GLY A 1 747 ? -3.510 -37.795 77.758 1.00 25.54 ? 774 GLY A O 1 ATOM 5793 N N . ASP A 1 748 ? -1.864 -39.332 77.835 1.00 19.40 ? 775 ASP A N 1 ATOM 5794 C CA . ASP A 1 748 ? -2.447 -40.078 78.950 1.00 23.15 ? 775 ASP A CA 1 ATOM 5795 C C . ASP A 1 748 ? -1.612 -40.027 80.225 1.00 26.19 ? 775 ASP A C 1 ATOM 5796 O O . ASP A 1 748 ? -1.544 -41.002 80.977 1.00 26.70 ? 775 ASP A O 1 ATOM 5797 C CB . ASP A 1 748 ? -2.686 -41.531 78.540 1.00 23.50 ? 775 ASP A CB 1 ATOM 5798 C CG . ASP A 1 748 ? -1.543 -42.095 77.730 1.00 22.91 ? 775 ASP A CG 1 ATOM 5799 O OD1 . ASP A 1 748 ? -0.611 -41.320 77.430 1.00 20.18 ? 775 ASP A OD1 1 ATOM 5800 O OD2 . ASP A 1 748 ? -1.584 -43.297 77.381 1.00 24.67 1 775 ASP A OD2 1 ATOM 5801 N N . ARG A 1 749 ? -0.986 -38.879 80.459 1.00 26.99 ? 776 ARG A N 1 ATOM 5802 C CA . ARG A 1 749 ? -0.174 -38.662 81.645 1.00 24.23 ? 776 ARG A CA 1 ATOM 5803 C C . ARG A 1 749 ? -0.992 -38.964 82.895 1.00 30.85 ? 776 ARG A C 1 ATOM 5804 O O . ARG A 1 749 ? -0.613 -39.811 83.702 1.00 40.37 ? 776 ARG A O 1 ATOM 5805 C CB . ARG A 1 749 ? 0.328 -37.219 81.674 1.00 24.49 ? 776 ARG A CB 1 ATOM 5806 C CG . ARG A 1 749 ? 1.763 -37.062 82.135 1.00 21.54 ? 776 ARG A CG 1 ATOM 5807 C CD . ARG A 1 749 ? 2.200 -35.609 82.083 1.00 19.84 ? 776 ARG A CD 1 ATOM 5808 N NE . ARG A 1 749 ? 1.233 -34.727 82.727 1.00 26.47 ? 776 ARG A NE 1 ATOM 5809 C CZ . ARG A 1 749 ? 1.471 -33.458 83.043 1.00 35.74 ? 776 ARG A CZ 1 ATOM 5810 N NH1 . ARG A 1 749 ? 2.653 -32.913 82.780 1.00 28.41 1 776 ARG A NH1 1 ATOM 5811 N NH2 . ARG A 1 749 ? 0.527 -32.732 83.627 1.00 40.49 ? 776 ARG A NH2 1 ATOM 5812 N N . ASN A 1 750 ? -2.133 -38.296 83.031 1.00 32.23 ? 777 ASN A N 1 ATOM 5813 C CA . ASN A 1 750 ? -3.004 -38.486 84.191 1.00 37.01 ? 777 ASN A CA 1 ATOM 5814 C C . ASN A 1 750 ? -3.502 -39.920 84.370 1.00 38.83 ? 777 ASN A C 1 ATOM 5815 O O . ASN A 1 750 ? -4.095 -40.249 85.396 1.00 42.94 ? 777 ASN A O 1 ATOM 5816 C CB . ASN A 1 750 ? -4.189 -37.515 84.142 1.00 35.16 ? 777 ASN A CB 1 ATOM 5817 C CG . ASN A 1 750 ? -3.814 -36.113 84.597 1.00 47.53 ? 777 ASN A CG 1 ATOM 5818 O OD1 . ASN A 1 750 ? -4.053 -35.737 85.747 1.00 48.56 ? 777 ASN A OD1 1 ATOM 5819 N ND2 . ASN A 1 750 ? -3.218 -35.335 83.696 1.00 40.10 ? 777 ASN A ND2 1 ATOM 5820 N N . GLU A 1 751 ? -3.252 -40.766 83.374 1.00 38.42 ? 778 GLU A N 1 ATOM 5821 C CA . GLU A 1 751 ? -3.706 -42.153 83.398 1.00 38.72 ? 778 GLU A CA 1 ATOM 5822 C C . GLU A 1 751 ? -2.567 -43.126 83.675 1.00 36.10 ? 778 GLU A C 1 ATOM 5823 O O . GLU A 1 751 ? -2.803 -44.316 83.869 1.00 42.03 ? 778 GLU A O 1 ATOM 5824 C CB . GLU A 1 751 ? -4.387 -42.521 82.075 1.00 40.94 ? 778 GLU A CB 1 ATOM 5825 C CG . GLU A 1 751 ? -5.728 -41.836 81.840 1.00 40.66 ? 778 GLU A CG 1 ATOM 5826 C CD . GLU A 1 751 ? -6.829 -42.389 82.726 1.00 52.51 ? 778 GLU A CD 1 ATOM 5827 O OE1 . GLU A 1 751 ? -6.959 -41.927 83.881 1.00 45.16 ? 778 GLU A OE1 1 ATOM 5828 O OE2 . GLU A 1 751 ? -7.565 -43.289 82.266 1.00 60.68 1 778 GLU A OE2 1 ATOM 5829 N N . MET A 1 752 ? -1.336 -42.624 83.687 1.00 33.10 ? 779 MET A N 1 ATOM 5830 C CA . MET A 1 752 ? -0.179 -43.472 83.964 1.00 32.70 ? 779 MET A CA 1 ATOM 5831 C C . MET A 1 752 ? -0.149 -43.925 85.423 1.00 35.06 ? 779 MET A C 1 ATOM 5832 O O . MET A 1 752 ? -0.268 -43.109 86.341 1.00 32.79 ? 779 MET A O 1 ATOM 5833 C CB . MET A 1 752 ? 1.118 -42.754 83.607 1.00 26.99 ? 779 MET A CB 1 ATOM 5834 C CG . MET A 1 752 ? 1.233 -42.401 82.143 1.00 24.08 ? 779 MET A CG 1 ATOM 5835 S SD . MET A 1 752 ? 2.807 -41.620 81.756 1.00 21.06 ? 779 MET A SD 1 ATOM 5836 C CE . MET A 1 752 ? 3.943 -42.963 82.085 1.00 19.40 ? 779 MET A CE 1 ATOM 5837 N N . MET A 1 753 ? 0.027 -45.228 85.622 1.00 33.69 ? 780 MET A N 1 ATOM 5838 C CA . MET A 1 753 ? -0.116 -45.837 86.938 1.00 33.77 ? 780 MET A CA 1 ATOM 5839 C C . MET A 1 753 ? 1.159 -46.487 87.460 1.00 38.88 ? 780 MET A C 1 ATOM 5840 O O . MET A 1 753 ? 2.016 -46.902 86.684 1.00 35.81 ? 780 MET A O 1 ATOM 5841 C CB . MET A 1 753 ? -1.219 -46.887 86.894 1.00 30.46 ? 780 MET A CB 1 ATOM 5842 C CG . MET A 1 753 ? -2.580 -46.318 86.604 1.00 33.32 ? 780 MET A CG 1 ATOM 5843 S SD . MET A 1 753 ? -3.080 -45.240 87.943 1.00 37.08 ? 780 MET A SD 1 ATOM 5844 C CE . MET A 1 753 ? -2.839 -46.336 89.338 1.00 44.43 ? 780 MET A CE 1 ATOM 5845 N N . CYS A 1 754 ? 1.262 -46.579 88.784 1.00 44.21 ? 781 CYS A N 1 ATOM 5846 C CA . CYS A 1 754 ? 2.355 -47.288 89.446 1.00 43.14 ? 781 CYS A CA 1 ATOM 5847 C C . CYS A 1 754 ? 1.878 -48.633 89.995 1.00 55.86 ? 781 CYS A C 1 ATOM 5848 O O . CYS A 1 754 ? 0.678 -48.843 90.186 1.00 58.04 ? 781 CYS A O 1 ATOM 5849 C CB . CYS A 1 754 ? 2.939 -46.441 90.575 1.00 38.07 ? 781 CYS A CB 1 ATOM 5850 S SG . CYS A 1 754 ? 3.967 -45.065 90.022 1.00 44.98 ? 781 CYS A SG 1 ATOM 5851 N N . VAL A 1 755 ? 2.817 -49.540 90.250 1.00 55.09 ? 782 VAL A N 1 ATOM 5852 C CA . VAL A 1 755 ? 2.473 -50.885 90.712 1.00 59.23 ? 782 VAL A CA 1 ATOM 5853 C C . VAL A 1 755 ? 3.204 -51.272 91.998 1.00 63.34 ? 782 VAL A C 1 ATOM 5854 O O . VAL A 1 755 ? 3.671 -52.403 92.147 1.00 63.10 ? 782 VAL A O 1 ATOM 5855 C CB . VAL A 1 755 ? 2.746 -51.948 89.621 1.00 56.78 ? 782 VAL A CB 1 ATOM 5856 C CG1 . VAL A 1 755 ? 1.715 -51.840 88.500 1.00 55.45 ? 782 VAL A CG1 1 ATOM 5857 C CG2 . VAL A 1 755 ? 4.163 -51.813 89.077 1.00 45.22 ? 782 VAL A CG2 1 ATOM 5858 N N . ASN A 1 756 ? 3.286 -50.332 92.933 1.00 64.31 ? 783 ASN A N 1 ATOM 5859 C CA . ASN A 1 756 ? 4.022 -50.560 94.169 1.00 60.53 ? 783 ASN A CA 1 ATOM 5860 C C . ASN A 1 756 ? 3.149 -50.478 95.421 1.00 65.93 ? 783 ASN A C 1 ATOM 5861 O O . ASN A 1 756 ? 3.512 -49.819 96.394 1.00 69.55 ? 783 ASN A O 1 ATOM 5862 C CB . ASN A 1 756 ? 5.194 -49.579 94.271 1.00 61.16 ? 783 ASN A CB 1 ATOM 5863 C CG . ASN A 1 756 ? 6.189 -49.733 93.128 1.00 54.63 ? 783 ASN A CG 1 ATOM 5864 O OD1 . ASN A 1 756 ? 6.488 -50.846 92.693 1.00 51.70 ? 783 ASN A OD1 1 ATOM 5865 N ND2 . ASN A 1 756 ? 6.703 -48.612 92.638 1.00 44.04 ? 783 ASN A ND2 1 ATOM 5866 N N . ALA A 1 757 ? 2.001 -51.151 95.388 1.00 72.15 ? 784 ALA A N 1 ATOM 5867 C CA . ALA A 1 757 ? 1.096 -51.200 96.536 1.00 64.07 ? 784 ALA A CA 1 ATOM 5868 C C . ALA A 1 757 ? 0.244 -52.464 96.512 1.00 62.90 ? 784 ALA A C 1 ATOM 5869 O O . ALA A 1 757 ? 0.354 -53.280 95.597 1.00 68.56 ? 784 ALA A O 1 ATOM 5870 C CB . ALA A 1 757 ? 0.210 -49.963 96.579 1.00 54.11 ? 784 ALA A CB 1 ATOM 5871 N N . PRO A 1 760 ? -1.511 -49.327 93.901 1.00 68.09 ? 787 PRO A N 1 ATOM 5872 C CA . PRO A 1 760 ? -1.297 -48.505 92.708 1.00 57.77 ? 787 PRO A CA 1 ATOM 5873 C C . PRO A 1 760 ? -1.809 -47.078 92.875 1.00 52.60 ? 787 PRO A C 1 ATOM 5874 O O . PRO A 1 760 ? -2.920 -46.862 93.361 1.00 53.40 ? 787 PRO A O 1 ATOM 5875 C CB . PRO A 1 760 ? -2.115 -49.235 91.644 1.00 53.78 ? 787 PRO A CB 1 ATOM 5876 C CG . PRO A 1 760 ? -2.021 -50.664 92.046 1.00 62.04 ? 787 PRO A CG 1 ATOM 5877 C CD . PRO A 1 760 ? -2.007 -50.672 93.558 1.00 67.90 ? 787 PRO A CD 1 ATOM 5878 N N . THR A 1 761 ? -0.989 -46.113 92.477 1.00 46.58 ? 788 THR A N 1 ATOM 5879 C CA . THR A 1 761 ? -1.391 -44.715 92.471 1.00 46.72 ? 788 THR A CA 1 ATOM 5880 C C . THR A 1 761 ? -0.987 -44.087 91.148 1.00 39.66 ? 788 THR A C 1 ATOM 5881 O O . THR A 1 761 ? -0.003 -44.508 90.538 1.00 39.35 ? 788 THR A O 1 ATOM 5882 C CB . THR A 1 761 ? -0.718 -43.926 93.603 1.00 45.84 ? 788 THR A CB 1 ATOM 5883 O OG1 . THR A 1 761 ? 0.701 -44.111 93.530 1.00 40.40 ? 788 THR A OG1 1 ATOM 5884 C CG2 . THR A 1 761 ? -1.223 -44.394 94.961 1.00 46.23 ? 788 THR A CG2 1 ATOM 5885 N N . ARG A 1 762 ? -1.751 -43.092 90.706 1.00 36.46 ? 789 ARG A N 1 ATOM 5886 C CA . ARG A 1 762 ? -1.402 -42.333 89.512 1.00 36.21 ? 789 ARG A CA 1 ATOM 5887 C C . ARG A 1 762 ? 0.026 -41.827 89.630 1.00 37.56 ? 789 ARG A C 1 ATOM 5888 O O . ARG A 1 762 ? 0.470 -41.438 90.712 1.00 38.28 ? 789 ARG A O 1 ATOM 5889 C CB . ARG A 1 762 ? -2.337 -41.139 89.336 1.00 39.75 ? 789 ARG A CB 1 ATOM 5890 C CG . ARG A 1 762 ? -3.798 -41.486 89.116 1.00 46.18 ? 789 ARG A CG 1 ATOM 5891 C CD . ARG A 1 762 ? -4.618 -40.210 89.044 1.00 47.22 ? 789 ARG A CD 1 ATOM 5892 N NE . ARG A 1 762 ? -4.366 -39.368 90.213 1.00 59.38 ? 789 ARG A NE 1 ATOM 5893 C CZ . ARG A 1 762 ? -4.459 -38.041 90.223 1.00 59.60 ? 789 ARG A CZ 1 ATOM 5894 N NH1 . ARG A 1 762 ? -4.795 -37.384 89.118 1.00 58.37 1 789 ARG A NH1 1 ATOM 5895 N NH2 . ARG A 1 762 ? -4.211 -37.370 91.341 1.00 47.54 ? 789 ARG A NH2 1 ATOM 5896 N N . MET A 1 763 ? 0.750 -41.835 88.520 1.00 33.56 ? 790 MET A N 1 ATOM 5897 C CA . MET A 1 763 ? 2.130 -41.388 88.542 1.00 27.58 ? 790 MET A CA 1 ATOM 5898 C C . MET A 1 763 ? 2.197 -39.876 88.709 1.00 28.61 ? 790 MET A C 1 ATOM 5899 O O . MET A 1 763 ? 3.195 -39.339 89.178 1.00 28.82 ? 790 MET A O 1 ATOM 5900 C CB . MET A 1 763 ? 2.846 -41.815 87.270 1.00 22.48 ? 790 MET A CB 1 ATOM 5901 C CG . MET A 1 763 ? 4.343 -41.724 87.362 1.00 18.39 ? 790 MET A CG 1 ATOM 5902 S SD . MET A 1 763 ? 5.120 -42.424 85.903 1.00 21.98 ? 790 MET A SD 1 ATOM 5903 C CE . MET A 1 763 ? 4.292 -44.012 85.824 1.00 25.68 ? 790 MET A CE 1 ATOM 5904 N N . VAL A 1 764 ? 1.123 -39.191 88.332 1.00 34.32 ? 791 VAL A N 1 ATOM 5905 C CA . VAL A 1 764 ? 1.061 -37.741 88.473 1.00 35.29 ? 791 VAL A CA 1 ATOM 5906 C C . VAL A 1 764 ? 0.660 -37.362 89.893 1.00 37.28 ? 791 VAL A C 1 ATOM 5907 O O . VAL A 1 764 ? 0.313 -36.212 90.169 1.00 42.42 ? 791 VAL A O 1 ATOM 5908 C CB . VAL A 1 764 ? 0.079 -37.106 87.471 1.00 35.33 ? 791 VAL A CB 1 ATOM 5909 C CG1 . VAL A 1 764 ? 0.477 -37.468 86.050 1.00 35.83 ? 791 VAL A CG1 1 ATOM 5910 C CG2 . VAL A 1 764 ? -1.347 -37.551 87.762 1.00 38.37 ? 791 VAL A CG2 1 ATOM 5911 N N . GLU A 1 765 ? 0.704 -38.346 90.784 1.00 30.53 ? 792 GLU A N 1 ATOM 5912 C CA . GLU A 1 765 ? 0.448 -38.132 92.196 1.00 29.40 ? 792 GLU A CA 1 ATOM 5913 C C . GLU A 1 765 ? 1.752 -38.387 92.937 1.00 34.27 ? 792 GLU A C 1 ATOM 5914 O O . GLU A 1 765 ? 1.802 -38.381 94.167 1.00 33.92 ? 792 GLU A O 1 ATOM 5915 C CB . GLU A 1 765 ? -0.623 -39.103 92.678 1.00 31.87 ? 792 GLU A CB 1 ATOM 5916 C CG . GLU A 1 765 ? -1.832 -38.449 93.305 1.00 32.97 ? 792 GLU A CG 1 ATOM 5917 C CD . GLU A 1 765 ? -2.894 -39.462 93.692 1.00 44.85 ? 792 GLU A CD 1 ATOM 5918 O OE1 . GLU A 1 765 ? -2.672 -40.229 94.655 1.00 49.41 ? 792 GLU A OE1 1 ATOM 5919 O OE2 . GLU A 1 765 ? -3.949 -39.496 93.024 1.00 41.59 1 792 GLU A OE2 1 ATOM 5920 N N . LEU A 1 766 ? 2.809 -38.615 92.164 1.00 35.05 ? 793 LEU A N 1 ATOM 5921 C CA . LEU A 1 766 ? 4.110 -38.996 92.704 1.00 32.55 ? 793 LEU A CA 1 ATOM 5922 C C . LEU A 1 766 ? 5.129 -37.874 92.576 1.00 34.54 ? 793 LEU A C 1 ATOM 5923 O O . LEU A 1 766 ? 5.046 -37.042 91.673 1.00 35.10 ? 793 LEU A O 1 ATOM 5924 C CB . LEU A 1 766 ? 4.641 -40.240 91.987 1.00 30.83 ? 793 LEU A CB 1 ATOM 5925 C CG . LEU A 1 766 ? 4.271 -41.628 92.519 1.00 34.95 ? 793 LEU A CG 1 ATOM 5926 C CD1 . LEU A 1 766 ? 5.184 -42.011 93.671 1.00 38.69 ? 793 LEU A CD1 1 ATOM 5927 C CD2 . LEU A 1 766 ? 2.804 -41.707 92.943 1.00 29.38 ? 793 LEU A CD2 1 ATOM 5928 N N . SER A 1 767 ? 6.093 -37.866 93.492 1.00 38.75 ? 794 SER A N 1 ATOM 5929 C CA . SER A 1 767 ? 7.205 -36.928 93.451 1.00 34.05 ? 794 SER A CA 1 ATOM 5930 C C . SER A 1 767 ? 8.464 -37.690 93.068 1.00 36.32 ? 794 SER A C 1 ATOM 5931 O O . SER A 1 767 ? 8.447 -38.917 92.979 1.00 39.27 ? 794 SER A O 1 ATOM 5932 C CB . SER A 1 767 ? 7.391 -36.265 94.816 1.00 31.50 ? 794 SER A CB 1 ATOM 5933 O OG . SER A 1 767 ? 8.520 -35.412 94.822 1.00 31.85 ? 794 SER A OG 1 ATOM 5934 N N . THR A 1 768 ? 9.558 -36.969 92.846 1.00 34.45 ? 795 THR A N 1 ATOM 5935 C CA . THR A 1 768 ? 10.824 -37.608 92.512 1.00 29.70 ? 795 THR A CA 1 ATOM 5936 C C . THR A 1 768 ? 11.570 -38.010 93.782 1.00 40.21 ? 795 THR A C 1 ATOM 5937 O O . THR A 1 768 ? 12.784 -38.217 93.760 1.00 43.14 ? 795 THR A O 1 ATOM 5938 C CB . THR A 1 768 ? 11.711 -36.676 91.683 1.00 22.94 ? 795 THR A CB 1 ATOM 5939 O OG1 . THR A 1 768 ? 12.440 -35.806 92.554 1.00 28.84 ? 795 THR A OG1 1 ATOM 5940 C CG2 . THR A 1 768 ? 10.864 -35.842 90.752 1.00 25.24 ? 795 THR A CG2 1 ATOM 5941 N N . ASN A 1 769 ? 10.835 -38.118 94.887 1.00 40.96 ? 796 ASN A N 1 ATOM 5942 C CA . ASN A 1 769 ? 11.420 -38.431 96.187 1.00 40.02 ? 796 ASN A CA 1 ATOM 5943 C C . ASN A 1 769 ? 10.655 -39.520 96.927 1.00 41.46 ? 796 ASN A C 1 ATOM 5944 O O . ASN A 1 769 ? 11.198 -40.164 97.823 1.00 44.41 ? 796 ASN A O 1 ATOM 5945 C CB . ASN A 1 769 ? 11.512 -37.174 97.050 1.00 40.60 ? 796 ASN A CB 1 ATOM 5946 C CG . ASN A 1 769 ? 12.476 -36.152 96.484 1.00 44.42 ? 796 ASN A CG 1 ATOM 5947 O OD1 . ASN A 1 769 ? 13.609 -36.483 96.125 1.00 49.45 ? 796 ASN A OD1 1 ATOM 5948 N ND2 . ASN A 1 769 ? 12.026 -34.902 96.389 1.00 34.95 ? 796 ASN A ND2 1 ATOM 5949 N N . ASP A 1 770 ? 9.392 -39.714 96.557 1.00 42.02 ? 797 ASP A N 1 ATOM 5950 C CA . ASP A 1 770 ? 8.622 -40.854 97.045 1.00 44.81 ? 797 ASP A CA 1 ATOM 5951 C C . ASP A 1 770 ? 9.283 -42.112 96.497 1.00 39.65 ? 797 ASP A C 1 ATOM 5952 O O . ASP A 1 770 ? 9.232 -43.185 97.102 1.00 33.59 ? 797 ASP A O 1 ATOM 5953 C CB . ASP A 1 770 ? 7.170 -40.798 96.548 1.00 42.41 ? 797 ASP A CB 1 ATOM 5954 C CG . ASP A 1 770 ? 6.409 -39.587 97.062 1.00 40.53 ? 797 ASP A CG 1 ATOM 5955 O OD1 . ASP A 1 770 ? 5.986 -39.602 98.238 1.00 49.49 ? 797 ASP A OD1 1 ATOM 5956 O OD2 . ASP A 1 770 ? 6.211 -38.631 96.283 1.00 36.12 1 797 ASP A OD2 1 ATOM 5957 N N . ILE A 1 771 ? 9.903 -41.950 95.334 1.00 35.85 ? 798 ILE A N 1 ATOM 5958 C CA . ILE A 1 771 ? 10.530 -43.039 94.611 1.00 37.48 ? 798 ILE A CA 1 ATOM 5959 C C . ILE A 1 771 ? 12.034 -43.052 94.846 1.00 46.45 ? 798 ILE A C 1 ATOM 5960 O O . ILE A 1 771 ? 12.687 -44.089 94.714 1.00 46.28 ? 798 ILE A O 1 ATOM 5961 C CB . ILE A 1 771 ? 10.293 -42.873 93.109 1.00 39.47 ? 798 ILE A CB 1 ATOM 5962 C CG1 . ILE A 1 771 ? 10.537 -41.415 92.710 1.00 37.29 ? 798 ILE A CG1 1 ATOM 5963 C CG2 . ILE A 1 771 ? 8.881 -43.281 92.748 1.00 38.81 ? 798 ILE A CG2 1 ATOM 5964 C CD1 . ILE A 1 771 ? 10.442 -41.158 91.231 1.00 34.18 ? 798 ILE A CD1 1 ATOM 5965 N N . CYS A 1 772 ? 12.582 -41.893 95.194 1.00 49.73 ? 799 CYS A N 1 ATOM 5966 C CA . CYS A 1 772 ? 14.026 -41.751 95.325 1.00 53.16 ? 799 CYS A CA 1 ATOM 5967 C C . CYS A 1 772 ? 14.451 -41.268 96.710 1.00 55.66 ? 799 CYS A C 1 ATOM 5968 O O . CYS A 1 772 ? 14.234 -40.106 97.063 1.00 55.87 ? 799 CYS A O 1 ATOM 5969 C CB . CYS A 1 772 ? 14.565 -40.802 94.249 1.00 49.84 ? 799 CYS A CB 1 ATOM 5970 S SG . CYS A 1 772 ? 15.996 -41.436 93.346 1.00 47.80 ? 799 CYS A SG 1 ATOM 5971 N N . PRO A 1 773 ? 15.045 -42.172 97.505 1.00 52.76 ? 800 PRO A N 1 ATOM 5972 C CA . PRO A 1 773 ? 15.689 -41.806 98.771 1.00 56.74 ? 800 PRO A CA 1 ATOM 5973 C C . PRO A 1 773 ? 16.877 -40.865 98.551 1.00 51.25 ? 800 PRO A C 1 ATOM 5974 O O . PRO A 1 773 ? 16.687 -39.680 98.267 1.00 39.46 ? 800 PRO A O 1 ATOM 5975 C CB . PRO A 1 773 ? 16.179 -43.154 99.312 1.00 55.75 ? 800 PRO A CB 1 ATOM 5976 C CG . PRO A 1 773 ? 15.260 -44.159 98.704 1.00 49.05 ? 800 PRO A CG 1 ATOM 5977 C CD . PRO A 1 773 ? 14.956 -43.633 97.333 1.00 50.27 ? 800 PRO A CD 1 ATOM 5978 N N . ASP B 2 5 ? -48.615 -36.756 28.827 1.00 41.94 ? 5 ASP J N 1 ATOM 5979 C CA . ASP B 2 5 ? -48.879 -37.368 27.530 1.00 58.80 ? 5 ASP J CA 1 ATOM 5980 C C . ASP B 2 5 ? -49.736 -36.440 26.667 1.00 57.40 ? 5 ASP J C 1 ATOM 5981 O O . ASP B 2 5 ? -50.714 -36.867 26.048 1.00 44.21 ? 5 ASP J O 1 ATOM 5982 C CB . ASP B 2 5 ? -49.560 -38.731 27.710 1.00 57.29 ? 5 ASP J CB 1 ATOM 5983 C CG . ASP B 2 5 ? -49.615 -39.539 26.421 1.00 55.88 ? 5 ASP J CG 1 ATOM 5984 O OD1 . ASP B 2 5 ? -49.113 -39.055 25.383 1.00 54.62 1 5 ASP J OD1 1 ATOM 5985 O OD2 . ASP B 2 5 ? -50.155 -40.666 26.449 1.00 54.67 ? 5 ASP J OD2 1 ATOM 5986 N N . GLU B 2 6 ? -49.358 -35.165 26.635 1.00 49.96 ? 6 GLU J N 1 ATOM 5987 C CA . GLU B 2 6 ? -50.101 -34.155 25.892 1.00 38.43 ? 6 GLU J CA 1 ATOM 5988 C C . GLU B 2 6 ? -49.178 -33.054 25.380 1.00 38.67 ? 6 GLU J C 1 ATOM 5989 O O . GLU B 2 6 ? -48.130 -32.791 25.963 1.00 45.22 ? 6 GLU J O 1 ATOM 5990 C CB . GLU B 2 6 ? -51.207 -33.558 26.772 1.00 39.27 ? 6 GLU J CB 1 ATOM 5991 C CG . GLU B 2 6 ? -52.424 -34.470 26.950 1.00 46.82 ? 6 GLU J CG 1 ATOM 5992 C CD . GLU B 2 6 ? -53.378 -33.996 28.032 1.00 50.07 ? 6 GLU J CD 1 ATOM 5993 O OE1 . GLU B 2 6 ? -53.014 -33.062 28.782 1.00 44.39 ? 6 GLU J OE1 1 ATOM 5994 O OE2 . GLU B 2 6 ? -54.493 -34.563 28.129 1.00 39.91 1 6 GLU J OE2 1 ATOM 5995 N N . ARG B 2 7 ? -49.566 -32.424 24.276 1.00 40.79 ? 7 ARG J N 1 ATOM 5996 C CA . ARG B 2 7 ? -48.851 -31.262 23.757 1.00 34.37 ? 7 ARG J CA 1 ATOM 5997 C C . ARG B 2 7 ? -49.867 -30.187 23.377 1.00 31.09 ? 7 ARG J C 1 ATOM 5998 O O . ARG B 2 7 ? -50.931 -30.494 22.843 1.00 33.57 ? 7 ARG J O 1 ATOM 5999 C CB . ARG B 2 7 ? -47.982 -31.646 22.553 1.00 32.83 ? 7 ARG J CB 1 ATOM 6000 C CG . ARG B 2 7 ? -47.174 -30.494 21.962 1.00 32.13 ? 7 ARG J CG 1 ATOM 6001 C CD . ARG B 2 7 ? -46.178 -30.988 20.924 1.00 34.85 ? 7 ARG J CD 1 ATOM 6002 N NE . ARG B 2 7 ? -45.621 -29.900 20.122 1.00 35.38 ? 7 ARG J NE 1 ATOM 6003 C CZ . ARG B 2 7 ? -45.293 -30.015 18.836 1.00 35.97 ? 7 ARG J CZ 1 ATOM 6004 N NH1 . ARG B 2 7 ? -45.467 -31.170 18.206 1.00 30.60 1 7 ARG J NH1 1 ATOM 6005 N NH2 . ARG B 2 7 ? -44.795 -28.979 18.173 1.00 32.80 ? 7 ARG J NH2 1 ATOM 6006 N N . PHE B 2 8 ? -49.544 -28.930 23.667 1.00 28.70 ? 8 PHE J N 1 ATOM 6007 C CA . PHE B 2 8 ? -50.456 -27.823 23.389 1.00 28.05 ? 8 PHE J CA 1 ATOM 6008 C C . PHE B 2 8 ? -49.956 -26.951 22.240 1.00 30.66 ? 8 PHE J C 1 ATOM 6009 O O . PHE B 2 8 ? -48.751 -26.842 22.013 1.00 40.34 ? 8 PHE J O 1 ATOM 6010 C CB . PHE B 2 8 ? -50.696 -26.998 24.656 1.00 28.64 ? 8 PHE J CB 1 ATOM 6011 C CG . PHE B 2 8 ? -51.509 -27.723 25.693 1.00 33.45 ? 8 PHE J CG 1 ATOM 6012 C CD1 . PHE B 2 8 ? -50.962 -28.768 26.414 1.00 28.94 ? 8 PHE J CD1 1 ATOM 6013 C CD2 . PHE B 2 8 ? -52.826 -27.372 25.931 1.00 39.06 ? 8 PHE J CD2 1 ATOM 6014 C CE1 . PHE B 2 8 ? -51.708 -29.446 27.355 1.00 31.05 ? 8 PHE J CE1 1 ATOM 6015 C CE2 . PHE B 2 8 ? -53.579 -28.046 26.874 1.00 33.62 ? 8 PHE J CE2 1 ATOM 6016 C CZ . PHE B 2 8 ? -53.017 -29.085 27.585 1.00 35.91 ? 8 PHE J CZ 1 ATOM 6017 N N . LEU B 2 9 ? -50.889 -26.337 21.519 1.00 25.82 ? 9 LEU J N 1 ATOM 6018 C CA . LEU B 2 9 ? -50.574 -25.587 20.299 1.00 22.68 ? 9 LEU J CA 1 ATOM 6019 C C . LEU B 2 9 ? -49.600 -24.426 20.525 1.00 22.12 ? 9 LEU J C 1 ATOM 6020 O O . LEU B 2 9 ? -48.918 -23.983 19.600 1.00 17.47 ? 9 LEU J O 1 ATOM 6021 C CB . LEU B 2 9 ? -51.860 -25.073 19.640 1.00 21.71 ? 9 LEU J CB 1 ATOM 6022 C CG . LEU B 2 9 ? -52.770 -26.090 18.943 1.00 21.30 ? 9 LEU J CG 1 ATOM 6023 C CD1 . LEU B 2 9 ? -51.976 -26.967 17.988 1.00 22.85 ? 9 LEU J CD1 1 ATOM 6024 C CD2 . LEU B 2 9 ? -53.533 -26.947 19.940 1.00 27.56 ? 9 LEU J CD2 1 ATOM 6025 N N . CYS B 2 10 ? -49.551 -23.938 21.760 1.00 25.78 ? 10 CYS J N 1 ATOM 6026 C CA . CYS B 2 10 ? -48.636 -22.876 22.141 1.00 21.92 ? 10 CYS J CA 1 ATOM 6027 C C . CYS B 2 10 ? -47.770 -23.320 23.308 1.00 33.72 ? 10 CYS J C 1 ATOM 6028 O O . CYS B 2 10 ? -48.264 -23.484 24.423 1.00 43.15 ? 10 CYS J O 1 ATOM 6029 C CB . CYS B 2 10 ? -49.412 -21.629 22.541 1.00 18.05 ? 10 CYS J CB 1 ATOM 6030 S SG . CYS B 2 10 ? -49.338 -20.322 21.330 1.00 14.25 ? 10 CYS J SG 1 ATOM 6031 N N . ARG B 2 11 ? -46.482 -23.520 23.051 1.00 37.88 ? 11 ARG J N 1 ATOM 6032 C CA . ARG B 2 11 ? -45.541 -23.841 24.116 1.00 38.17 ? 11 ARG J CA 1 ATOM 6033 C C . ARG B 2 11 ? -45.460 -22.683 25.101 1.00 30.38 ? 11 ARG J C 1 ATOM 6034 O O . ARG B 2 11 ? -45.239 -21.538 24.712 1.00 29.27 ? 11 ARG J O 1 ATOM 6035 C CB . ARG B 2 11 ? -44.152 -24.164 23.549 1.00 42.08 ? 11 ARG J CB 1 ATOM 6036 C CG . ARG B 2 11 ? -44.079 -25.492 22.802 1.00 43.35 ? 11 ARG J CG 1 ATOM 6037 C CD . ARG B 2 11 ? -42.664 -26.062 22.792 1.00 48.37 ? 11 ARG J CD 1 ATOM 6038 N NE . ARG B 2 11 ? -42.673 -27.522 22.682 1.00 65.70 ? 11 ARG J NE 1 ATOM 6039 C CZ . ARG B 2 11 ? -41.598 -28.298 22.807 1.00 57.35 ? 11 ARG J CZ 1 ATOM 6040 N NH1 . ARG B 2 11 ? -40.408 -27.762 23.048 1.00 44.97 1 11 ARG J NH1 1 ATOM 6041 N NH2 . ARG B 2 11 ? -41.714 -29.616 22.692 1.00 50.80 ? 11 ARG J NH2 1 ATOM 6042 N N . SER B 2 12 ? -45.660 -22.986 26.377 1.00 35.07 ? 12 SER J N 1 ATOM 6043 C CA . SER B 2 12 ? -45.562 -21.977 27.422 1.00 41.38 ? 12 SER J CA 1 ATOM 6044 C C . SER B 2 12 ? -44.643 -22.447 28.550 1.00 45.56 ? 12 SER J C 1 ATOM 6045 O O . SER B 2 12 ? -44.070 -23.538 28.491 1.00 40.70 ? 12 SER J O 1 ATOM 6046 C CB . SER B 2 12 ? -46.948 -21.636 27.973 1.00 36.22 ? 12 SER J CB 1 ATOM 6047 O OG . SER B 2 12 ? -47.447 -22.686 28.781 1.00 35.98 ? 12 SER J OG 1 ATOM 6048 N N . ILE B 2 13 ? -44.502 -21.617 29.577 1.00 47.83 ? 13 ILE J N 1 ATOM 6049 C CA . ILE B 2 13 ? -43.650 -21.947 30.716 1.00 55.19 ? 13 ILE J CA 1 ATOM 6050 C C . ILE B 2 13 ? -44.278 -21.502 32.045 1.00 55.85 ? 13 ILE J C 1 ATOM 6051 O O . ILE B 2 13 ? -44.161 -20.344 32.457 1.00 56.69 ? 13 ILE J O 1 ATOM 6052 C CB . ILE B 2 13 ? -42.207 -21.384 30.538 1.00 60.22 ? 13 ILE J CB 1 ATOM 6053 C CG1 . ILE B 2 13 ? -41.387 -21.555 31.820 1.00 59.67 ? 13 ILE J CG1 1 ATOM 6054 C CG2 . ILE B 2 13 ? -42.230 -19.925 30.082 1.00 52.53 ? 13 ILE J CG2 1 ATOM 6055 C CD1 . ILE B 2 13 ? -41.172 -23.002 32.222 1.00 65.42 ? 13 ILE J CD1 1 ATOM 6056 N N . ARG B 2 14 ? -44.958 -22.433 32.707 1.00 57.02 ? 14 ARG J N 1 ATOM 6057 C CA . ARG B 2 14 ? -45.637 -22.119 33.956 1.00 57.95 ? 14 ARG J CA 1 ATOM 6058 C C . ARG B 2 14 ? -44.617 -21.860 35.058 1.00 66.49 ? 14 ARG J C 1 ATOM 6059 O O . ARG B 2 14 ? -43.528 -22.434 35.054 1.00 64.22 ? 14 ARG J O 1 ATOM 6060 C CB . ARG B 2 14 ? -46.606 -23.233 34.362 1.00 61.62 ? 14 ARG J CB 1 ATOM 6061 C CG . ARG B 2 14 ? -45.929 -24.542 34.731 1.00 77.02 ? 14 ARG J CG 1 ATOM 6062 C CD . ARG B 2 14 ? -46.858 -25.443 35.539 1.00 85.02 ? 14 ARG J CD 1 ATOM 6063 N NE . ARG B 2 14 ? -46.151 -26.590 36.107 1.00 85.35 ? 14 ARG J NE 1 ATOM 6064 C CZ . ARG B 2 14 ? -45.502 -26.569 37.268 1.00 76.98 ? 14 ARG J CZ 1 ATOM 6065 N NH1 . ARG B 2 14 ? -45.464 -25.456 37.990 1.00 73.97 1 14 ARG J NH1 1 ATOM 6066 N NH2 . ARG B 2 14 ? -44.885 -27.659 37.706 1.00 70.75 ? 14 ARG J NH2 1 ATOM 6067 N N . LYS B 2 15 ? -44.973 -20.986 35.994 1.00 69.83 ? 15 LYS J N 1 ATOM 6068 C CA . LYS B 2 15 ? -44.049 -20.568 37.041 1.00 64.95 ? 15 LYS J CA 1 ATOM 6069 C C . LYS B 2 15 ? -44.730 -20.571 38.412 1.00 67.52 ? 15 LYS J C 1 ATOM 6070 O O . LYS B 2 15 ? -45.839 -21.091 38.566 1.00 58.46 ? 15 LYS J O 1 ATOM 6071 C CB . LYS B 2 15 ? -43.488 -19.180 36.714 1.00 58.57 ? 15 LYS J CB 1 ATOM 6072 C CG . LYS B 2 15 ? -42.042 -18.964 37.122 1.00 61.01 ? 15 LYS J CG 1 ATOM 6073 C CD . LYS B 2 15 ? -41.460 -17.730 36.449 1.00 61.32 ? 15 LYS J CD 1 ATOM 6074 C CE . LYS B 2 15 ? -41.509 -17.862 34.932 1.00 67.90 ? 15 LYS J CE 1 ATOM 6075 N NZ . LYS B 2 15 ? -40.836 -16.726 34.240 1.00 67.38 1 15 LYS J NZ 1 ATOM 6076 N N . LEU B 2 16 ? -44.058 -19.989 39.402 1.00 73.63 ? 16 LEU J N 1 ATOM 6077 C CA . LEU B 2 16 ? -44.543 -19.988 40.775 1.00 67.29 ? 16 LEU J CA 1 ATOM 6078 C C . LEU B 2 16 ? -43.860 -18.872 41.551 1.00 57.95 ? 16 LEU J C 1 ATOM 6079 O O . LEU B 2 16 ? -42.957 -19.133 42.335 1.00 59.01 ? 16 LEU J O 1 ATOM 6080 C CB . LEU B 2 16 ? -44.227 -21.332 41.437 1.00 68.73 ? 16 LEU J CB 1 ATOM 6081 C CG . LEU B 2 16 ? -45.210 -21.932 42.448 1.00 75.29 ? 16 LEU J CG 1 ATOM 6082 C CD1 . LEU B 2 16 ? -44.672 -23.257 42.997 1.00 60.93 ? 16 LEU J CD1 1 ATOM 6083 C CD2 . LEU B 2 16 ? -45.525 -20.960 43.580 1.00 72.70 ? 16 LEU J CD2 1 ATOM 6084 N N . VAL B 2 17 ? -44.289 -17.632 41.337 1.00 66.56 ? 17 VAL J N 1 ATOM 6085 C CA . VAL B 2 17 ? -43.640 -16.491 41.981 1.00 72.72 ? 17 VAL J CA 1 ATOM 6086 C C . VAL B 2 17 ? -44.594 -15.590 42.777 1.00 75.40 ? 17 VAL J C 1 ATOM 6087 O O . VAL B 2 17 ? -45.755 -15.406 42.405 1.00 65.78 ? 17 VAL J O 1 ATOM 6088 C CB . VAL B 2 17 ? -42.855 -15.636 40.960 1.00 65.62 ? 17 VAL J CB 1 ATOM 6089 C CG1 . VAL B 2 17 ? -41.654 -16.406 40.438 1.00 56.00 ? 17 VAL J CG1 1 ATOM 6090 C CG2 . VAL B 2 17 ? -43.759 -15.201 39.817 1.00 57.68 ? 17 VAL J CG2 1 ATOM 6091 N N . TYR B 2 18 ? -44.085 -15.040 43.879 1.00 80.03 ? 18 TYR J N 1 ATOM 6092 C CA . TYR B 2 18 ? -44.839 -14.106 44.715 1.00 79.63 ? 18 TYR J CA 1 ATOM 6093 C C . TYR B 2 18 ? -44.163 -12.736 44.700 1.00 74.86 ? 18 TYR J C 1 ATOM 6094 O O . TYR B 2 18 ? -44.611 -11.813 44.020 1.00 73.98 ? 18 TYR J O 1 ATOM 6095 C CB . TYR B 2 18 ? -44.930 -14.609 46.162 1.00 73.18 ? 18 TYR J CB 1 ATOM 6096 C CG . TYR B 2 18 ? -45.863 -15.784 46.397 1.00 71.69 ? 18 TYR J CG 1 ATOM 6097 C CD1 . TYR B 2 18 ? -45.869 -16.882 45.544 1.00 69.99 ? 18 TYR J CD1 1 ATOM 6098 C CD2 . TYR B 2 18 ? -46.713 -15.808 47.497 1.00 65.80 ? 18 TYR J CD2 1 ATOM 6099 C CE1 . TYR B 2 18 ? -46.708 -17.959 45.764 1.00 61.09 ? 18 TYR J CE1 1 ATOM 6100 C CE2 . TYR B 2 18 ? -47.554 -16.885 47.727 1.00 62.58 ? 18 TYR J CE2 1 ATOM 6101 C CZ . TYR B 2 18 ? -47.545 -17.957 46.855 1.00 62.31 ? 18 TYR J CZ 1 ATOM 6102 O OH . TYR B 2 18 ? -48.375 -19.034 47.070 1.00 67.92 ? 18 TYR J OH 1 ATOM 6103 N N . ILE B 2 42 ? -48.037 -16.548 43.241 1.00 60.24 ? 42 ILE J N 1 ATOM 6104 C CA . ILE B 2 42 ? -49.061 -17.379 42.616 1.00 65.84 ? 42 ILE J CA 1 ATOM 6105 C C . ILE B 2 42 ? -48.495 -18.117 41.399 1.00 65.71 ? 42 ILE J C 1 ATOM 6106 O O . ILE B 2 42 ? -47.582 -17.624 40.731 1.00 60.50 ? 42 ILE J O 1 ATOM 6107 C CB . ILE B 2 42 ? -50.304 -16.540 42.211 1.00 50.03 ? 42 ILE J CB 1 ATOM 6108 C CG1 . ILE B 2 42 ? -51.493 -17.444 41.875 1.00 44.44 ? 42 ILE J CG1 1 ATOM 6109 C CG2 . ILE B 2 42 ? -49.979 -15.622 41.049 1.00 41.12 ? 42 ILE J CG2 1 ATOM 6110 C CD1 . ILE B 2 42 ? -51.837 -18.441 42.967 1.00 53.43 ? 42 ILE J CD1 1 ATOM 6111 N N . GLN B 2 43 ? -49.024 -19.309 41.132 1.00 64.62 ? 43 GLN J N 1 ATOM 6112 C CA . GLN B 2 43 ? -48.625 -20.076 39.957 1.00 54.79 ? 43 GLN J CA 1 ATOM 6113 C C . GLN B 2 43 ? -49.031 -19.354 38.681 1.00 49.60 ? 43 GLN J C 1 ATOM 6114 O O . GLN B 2 43 ? -50.200 -19.022 38.490 1.00 58.45 ? 43 GLN J O 1 ATOM 6115 C CB . GLN B 2 43 ? -49.254 -21.467 39.978 1.00 49.75 ? 43 GLN J CB 1 ATOM 6116 C CG . GLN B 2 43 ? -49.256 -22.133 38.617 1.00 48.23 ? 43 GLN J CG 1 ATOM 6117 C CD . GLN B 2 43 ? -49.475 -23.624 38.691 1.00 49.17 ? 43 GLN J CD 1 ATOM 6118 O OE1 . GLN B 2 43 ? -50.589 -24.095 38.932 1.00 44.71 ? 43 GLN J OE1 1 ATOM 6119 N NE2 . GLN B 2 43 ? -48.407 -24.382 38.482 1.00 54.09 ? 43 GLN J NE2 1 ATOM 6120 N N . ILE B 2 44 ? -48.068 -19.108 37.803 1.00 43.55 ? 44 ILE J N 1 ATOM 6121 C CA . ILE B 2 44 ? -48.364 -18.390 36.573 1.00 43.72 ? 44 ILE J CA 1 ATOM 6122 C C . ILE B 2 44 ? -47.873 -19.125 35.324 1.00 50.47 ? 44 ILE J C 1 ATOM 6123 O O . ILE B 2 44 ? -46.702 -19.482 35.223 1.00 56.18 ? 44 ILE J O 1 ATOM 6124 C CB . ILE B 2 44 ? -47.799 -16.953 36.615 1.00 42.19 ? 44 ILE J CB 1 ATOM 6125 C CG1 . ILE B 2 44 ? -46.281 -16.958 36.786 1.00 46.71 ? 44 ILE J CG1 1 ATOM 6126 C CG2 . ILE B 2 44 ? -48.408 -16.185 37.757 1.00 46.30 ? 44 ILE J CG2 1 ATOM 6127 C CD1 . ILE B 2 44 ? -45.539 -16.453 35.572 1.00 47.86 ? 44 ILE J CD1 1 ATOM 6128 N N . GLU B 2 45 ? -48.781 -19.368 34.383 1.00 45.51 ? 45 GLU J N 1 ATOM 6129 C CA . GLU B 2 45 ? -48.390 -19.886 33.076 1.00 42.47 ? 45 GLU J CA 1 ATOM 6130 C C . GLU B 2 45 ? -48.063 -18.708 32.165 1.00 36.32 ? 45 GLU J C 1 ATOM 6131 O O . GLU B 2 45 ? -48.675 -17.648 32.261 1.00 32.60 ? 45 GLU J O 1 ATOM 6132 C CB . GLU B 2 45 ? -49.494 -20.745 32.461 1.00 37.72 ? 45 GLU J CB 1 ATOM 6133 C CG . GLU B 2 45 ? -49.089 -21.420 31.160 1.00 34.28 ? 45 GLU J CG 1 ATOM 6134 C CD . GLU B 2 45 ? -50.260 -22.068 30.446 1.00 42.21 ? 45 GLU J CD 1 ATOM 6135 O OE1 . GLU B 2 45 ? -50.064 -22.604 29.334 1.00 40.07 ? 45 GLU J OE1 1 ATOM 6136 O OE2 . GLU B 2 45 ? -51.381 -22.039 30.997 1.00 54.26 1 45 GLU J OE2 1 ATOM 6137 N N . GLU B 2 46 ? -47.091 -18.888 31.285 1.00 33.52 ? 46 GLU J N 1 ATOM 6138 C CA . GLU B 2 46 ? -46.629 -17.778 30.475 1.00 32.79 ? 46 GLU J CA 1 ATOM 6139 C C . GLU B 2 46 ? -46.119 -18.236 29.122 1.00 39.92 ? 46 GLU J C 1 ATOM 6140 O O . GLU B 2 46 ? -45.339 -19.184 29.029 1.00 39.41 ? 46 GLU J O 1 ATOM 6141 C CB . GLU B 2 46 ? -45.532 -17.018 31.214 1.00 37.47 ? 46 GLU J CB 1 ATOM 6142 C CG . GLU B 2 46 ? -44.786 -16.018 30.356 1.00 40.91 ? 46 GLU J CG 1 ATOM 6143 C CD . GLU B 2 46 ? -43.665 -15.334 31.111 1.00 51.81 ? 46 GLU J CD 1 ATOM 6144 O OE1 . GLU B 2 46 ? -42.888 -14.586 30.476 1.00 56.60 ? 46 GLU J OE1 1 ATOM 6145 O OE2 . GLU B 2 46 ? -43.561 -15.546 32.340 1.00 45.28 1 46 GLU J OE2 1 ATOM 6146 N N . CYS B 2 47 ? -46.565 -17.548 28.077 1.00 41.34 ? 47 CYS J N 1 ATOM 6147 C CA . CYS B 2 47 ? -46.136 -17.830 26.716 1.00 35.75 ? 47 CYS J CA 1 ATOM 6148 C C . CYS B 2 47 ? -44.623 -17.882 26.607 1.00 34.79 ? 47 CYS J C 1 ATOM 6149 O O . CYS B 2 47 ? -43.912 -17.239 27.374 1.00 41.86 ? 47 CYS J O 1 ATOM 6150 C CB . CYS B 2 47 ? -46.669 -16.756 25.768 1.00 30.55 ? 47 CYS J CB 1 ATOM 6151 S SG . CYS B 2 47 ? -47.829 -17.360 24.539 1.00 37.46 ? 47 CYS J SG 1 ATOM 6152 N N . GLU B 2 48 ? -44.140 -18.672 25.660 1.00 35.59 ? 48 GLU J N 1 ATOM 6153 C CA . GLU B 2 48 ? -42.747 -18.604 25.257 1.00 37.17 ? 48 GLU J CA 1 ATOM 6154 C C . GLU B 2 48 ? -42.677 -17.681 24.050 1.00 37.82 ? 48 GLU J C 1 ATOM 6155 O O . GLU B 2 48 ? -42.232 -16.535 24.144 1.00 34.15 ? 48 GLU J O 1 ATOM 6156 C CB . GLU B 2 48 ? -42.223 -19.992 24.886 1.00 36.71 ? 48 GLU J CB 1 ATOM 6157 C CG . GLU B 2 48 ? -40.839 -19.990 24.250 1.00 39.52 ? 48 GLU J CG 1 ATOM 6158 C CD . GLU B 2 48 ? -40.385 -21.375 23.822 1.00 55.30 ? 48 GLU J CD 1 ATOM 6159 O OE1 . GLU B 2 48 ? -40.449 -22.310 24.650 1.00 55.96 ? 48 GLU J OE1 1 ATOM 6160 O OE2 . GLU B 2 48 ? -39.969 -21.525 22.654 1.00 58.54 1 48 GLU J OE2 1 ATOM 6161 N N . GLY B 2 49 ? -43.152 -18.187 22.918 1.00 45.36 ? 49 GLY J N 1 ATOM 6162 C CA . GLY B 2 49 ? -43.137 -17.435 21.682 1.00 41.23 ? 49 GLY J CA 1 ATOM 6163 C C . GLY B 2 49 ? -44.461 -16.765 21.401 1.00 27.24 ? 49 GLY J C 1 ATOM 6164 O O . GLY B 2 49 ? -45.190 -17.182 20.504 1.00 22.51 ? 49 GLY J O 1 ATOM 6165 N N . ALA B 2 50 ? -44.770 -15.731 22.178 1.00 28.31 ? 50 ALA J N 1 ATOM 6166 C CA . ALA B 2 50 ? -45.961 -14.930 21.939 1.00 25.66 ? 50 ALA J CA 1 ATOM 6167 C C . ALA B 2 50 ? -45.781 -14.133 20.654 1.00 24.00 ? 50 ALA J C 1 ATOM 6168 O O . ALA B 2 50 ? -44.657 -13.781 20.287 1.00 23.13 ? 50 ALA J O 1 ATOM 6169 C CB . ALA B 2 50 ? -46.238 -14.005 23.113 1.00 19.27 ? 50 ALA J CB 1 ATOM 6170 N N . ASP B 2 51 ? -46.895 -13.885 19.966 1.00 22.93 ? 51 ASP J N 1 ATOM 6171 C CA . ASP B 2 51 ? -46.919 -13.148 18.701 1.00 24.18 ? 51 ASP J CA 1 ATOM 6172 C C . ASP B 2 51 ? -46.202 -13.908 17.578 1.00 23.72 ? 51 ASP J C 1 ATOM 6173 O O . ASP B 2 51 ? -46.027 -13.401 16.467 1.00 20.84 ? 51 ASP J O 1 ATOM 6174 C CB . ASP B 2 51 ? -46.356 -11.736 18.886 1.00 22.71 ? 51 ASP J CB 1 ATOM 6175 C CG . ASP B 2 51 ? -46.892 -11.061 20.135 1.00 24.03 ? 51 ASP J CG 1 ATOM 6176 O OD1 . ASP B 2 51 ? -48.126 -11.030 20.311 1.00 24.50 ? 51 ASP J OD1 1 ATOM 6177 O OD2 . ASP B 2 51 ? -46.082 -10.583 20.955 1.00 30.64 1 51 ASP J OD2 1 ATOM 6178 N N . GLN B 2 52 ? -45.812 -15.140 17.883 1.00 20.79 ? 52 GLN J N 1 ATOM 6179 C CA . GLN B 2 52 ? -45.169 -16.016 16.923 1.00 18.47 ? 52 GLN J CA 1 ATOM 6180 C C . GLN B 2 52 ? -46.118 -17.165 16.604 1.00 18.29 ? 52 GLN J C 1 ATOM 6181 O O . GLN B 2 52 ? -46.951 -17.525 17.436 1.00 20.86 ? 52 GLN J O 1 ATOM 6182 C CB . GLN B 2 52 ? -43.855 -16.543 17.504 1.00 24.62 ? 52 GLN J CB 1 ATOM 6183 C CG . GLN B 2 52 ? -42.843 -15.452 17.798 1.00 31.71 ? 52 GLN J CG 1 ATOM 6184 C CD . GLN B 2 52 ? -42.490 -14.640 16.561 1.00 37.48 ? 52 GLN J CD 1 ATOM 6185 O OE1 . GLN B 2 52 ? -42.251 -15.196 15.486 1.00 37.11 ? 52 GLN J OE1 1 ATOM 6186 N NE2 . GLN B 2 52 ? -42.461 -13.316 16.707 1.00 31.99 ? 52 GLN J NE2 1 ATOM 6187 N N . PRO B 2 53 ? -46.006 -17.730 15.391 1.00 14.99 ? 53 PRO J N 1 ATOM 6188 C CA . PRO B 2 53 ? -46.842 -18.839 14.916 1.00 14.38 ? 53 PRO J CA 1 ATOM 6189 C C . PRO B 2 53 ? -46.956 -19.980 15.919 1.00 19.24 ? 53 PRO J C 1 ATOM 6190 O O . PRO B 2 53 ? -45.995 -20.269 16.629 1.00 23.98 ? 53 PRO J O 1 ATOM 6191 C CB . PRO B 2 53 ? -46.088 -19.324 13.681 1.00 14.08 ? 53 PRO J CB 1 ATOM 6192 C CG . PRO B 2 53 ? -45.427 -18.106 13.157 1.00 14.79 ? 53 PRO J CG 1 ATOM 6193 C CD . PRO B 2 53 ? -45.067 -17.271 14.351 1.00 17.71 ? 53 PRO J CD 1 ATOM 6194 N N . CYS B 2 54 ? -48.119 -20.621 15.968 1.00 17.33 ? 54 CYS J N 1 ATOM 6195 C CA . CYS B 2 54 ? -48.344 -21.738 16.874 1.00 13.27 ? 54 CYS J CA 1 ATOM 6196 C C . CYS B 2 54 ? -47.721 -23.009 16.334 1.00 13.84 ? 54 CYS J C 1 ATOM 6197 O O . CYS B 2 54 ? -47.267 -23.061 15.194 1.00 14.55 ? 54 CYS J O 1 ATOM 6198 C CB . CYS B 2 54 ? -49.838 -21.972 17.065 1.00 15.22 ? 54 CYS J CB 1 ATOM 6199 S SG . CYS B 2 54 ? -50.811 -20.481 17.334 1.00 30.11 ? 54 CYS J SG 1 ATOM 6200 N N . ASP B 2 55 ? -47.705 -24.042 17.162 1.00 17.15 ? 55 ASP J N 1 ATOM 6201 C CA . ASP B 2 55 ? -47.291 -25.356 16.703 1.00 23.56 ? 55 ASP J CA 1 ATOM 6202 C C . ASP B 2 55 ? -48.381 -25.942 15.820 1.00 20.01 ? 55 ASP J C 1 ATOM 6203 O O . ASP B 2 55 ? -49.564 -25.690 16.040 1.00 17.37 ? 55 ASP J O 1 ATOM 6204 C CB . ASP B 2 55 ? -47.015 -26.282 17.885 1.00 31.17 ? 55 ASP J CB 1 ATOM 6205 C CG . ASP B 2 55 ? -45.697 -25.982 18.559 1.00 31.74 ? 55 ASP J CG 1 ATOM 6206 O OD1 . ASP B 2 55 ? -44.771 -25.530 17.849 1.00 25.30 ? 55 ASP J OD1 1 ATOM 6207 O OD2 . ASP B 2 55 ? -45.593 -26.201 19.789 1.00 32.61 1 55 ASP J OD2 1 ATOM 6208 N N . PHE B 2 56 ? -47.975 -26.729 14.831 1.00 20.56 ? 56 PHE J N 1 ATOM 6209 C CA . PHE B 2 56 ? -48.900 -27.251 13.837 1.00 18.35 ? 56 PHE J CA 1 ATOM 6210 C C . PHE B 2 56 ? -49.666 -26.091 13.227 1.00 18.75 ? 56 PHE J C 1 ATOM 6211 O O . PHE B 2 56 ? -50.878 -26.166 13.046 1.00 20.63 ? 56 PHE J O 1 ATOM 6212 C CB . PHE B 2 56 ? -49.881 -28.249 14.453 1.00 15.13 ? 56 PHE J CB 1 ATOM 6213 C CG . PHE B 2 56 ? -49.224 -29.338 15.245 1.00 19.62 ? 56 PHE J CG 1 ATOM 6214 C CD1 . PHE B 2 56 ? -48.841 -30.523 14.633 1.00 19.93 ? 56 PHE J CD1 1 ATOM 6215 C CD2 . PHE B 2 56 ? -48.998 -29.186 16.605 1.00 19.00 ? 56 PHE J CD2 1 ATOM 6216 C CE1 . PHE B 2 56 ? -48.241 -31.532 15.361 1.00 20.22 ? 56 PHE J CE1 1 ATOM 6217 C CE2 . PHE B 2 56 ? -48.399 -30.190 17.339 1.00 19.10 ? 56 PHE J CE2 1 ATOM 6218 C CZ . PHE B 2 56 ? -48.021 -31.365 16.717 1.00 23.40 ? 56 PHE J CZ 1 ATOM 6219 N N . ALA B 2 57 ? -48.955 -25.013 12.916 1.00 16.30 ? 57 ALA J N 1 ATOM 6220 C CA . ALA B 2 57 ? -49.585 -23.841 12.326 1.00 12.71 ? 57 ALA J CA 1 ATOM 6221 C C . ALA B 2 57 ? -50.050 -24.118 10.904 1.00 11.70 ? 57 ALA J C 1 ATOM 6222 O O . ALA B 2 57 ? -50.616 -23.244 10.254 1.00 12.40 ? 57 ALA J O 1 ATOM 6223 C CB . ALA B 2 57 ? -48.635 -22.664 12.350 1.00 16.92 ? 57 ALA J CB 1 ATOM 6224 N N . ALA B 2 58 ? -49.802 -25.334 10.427 1.00 12.79 ? 58 ALA J N 1 ATOM 6225 C CA . ALA B 2 58 ? -50.256 -25.759 9.110 1.00 14.48 ? 58 ALA J CA 1 ATOM 6226 C C . ALA B 2 58 ? -51.467 -26.679 9.195 1.00 16.09 ? 58 ALA J C 1 ATOM 6227 O O . ALA B 2 58 ? -52.124 -26.930 8.187 1.00 16.61 ? 58 ALA J O 1 ATOM 6228 C CB . ALA B 2 58 ? -49.133 -26.446 8.357 1.00 15.29 ? 58 ALA J CB 1 ATOM 6229 N N . ASN B 2 59 ? -51.766 -27.175 10.393 1.00 14.68 ? 59 ASN J N 1 ATOM 6230 C CA . ASN B 2 59 ? -52.907 -28.071 10.583 1.00 14.87 ? 59 ASN J CA 1 ATOM 6231 C C . ASN B 2 59 ? -54.248 -27.360 10.781 1.00 14.60 ? 59 ASN J C 1 ATOM 6232 O O . ASN B 2 59 ? -55.199 -27.938 11.301 1.00 16.30 ? 59 ASN J O 1 ATOM 6233 C CB . ASN B 2 59 ? -52.637 -29.035 11.738 1.00 12.86 ? 59 ASN J CB 1 ATOM 6234 C CG . ASN B 2 59 ? -51.488 -29.966 11.446 1.00 14.71 ? 59 ASN J CG 1 ATOM 6235 O OD1 . ASN B 2 59 ? -50.333 -29.543 11.402 1.00 18.33 ? 59 ASN J OD1 1 ATOM 6236 N ND2 . ASN B 2 59 ? -51.795 -31.243 11.232 1.00 11.90 ? 59 ASN J ND2 1 ATOM 6237 N N . PHE B 2 60 ? -54.324 -26.110 10.347 1.00 10.92 ? 60 PHE J N 1 ATOM 6238 C CA . PHE B 2 60 ? -55.529 -25.330 10.534 1.00 9.95 ? 60 PHE J CA 1 ATOM 6239 C C . PHE B 2 60 ? -56.143 -24.935 9.199 1.00 16.59 ? 60 PHE J C 1 ATOM 6240 O O . PHE B 2 60 ? -55.433 -24.855 8.196 1.00 21.03 ? 60 PHE J O 1 ATOM 6241 C CB . PHE B 2 60 ? -55.215 -24.101 11.377 1.00 10.32 ? 60 PHE J CB 1 ATOM 6242 C CG . PHE B 2 60 ? -54.947 -24.420 12.809 1.00 13.86 ? 60 PHE J CG 1 ATOM 6243 C CD1 . PHE B 2 60 ? -55.986 -24.726 13.662 1.00 13.65 ? 60 PHE J CD1 1 ATOM 6244 C CD2 . PHE B 2 60 ? -53.654 -24.432 13.303 1.00 18.95 ? 60 PHE J CD2 1 ATOM 6245 C CE1 . PHE B 2 60 ? -55.745 -25.029 14.986 1.00 15.50 ? 60 PHE J CE1 1 ATOM 6246 C CE2 . PHE B 2 60 ? -53.404 -24.733 14.631 1.00 15.81 ? 60 PHE J CE2 1 ATOM 6247 C CZ . PHE B 2 60 ? -54.449 -25.034 15.471 1.00 14.49 ? 60 PHE J CZ 1 ATOM 6248 N N . PRO B 2 61 ? -57.472 -24.709 9.181 1.00 13.73 ? 61 PRO J N 1 ATOM 6249 C CA . PRO B 2 61 ? -58.205 -24.265 7.991 1.00 8.70 ? 61 PRO J CA 1 ATOM 6250 C C . PRO B 2 61 ? -57.612 -22.993 7.402 1.00 9.50 ? 61 PRO J C 1 ATOM 6251 O O . PRO B 2 61 ? -56.935 -22.253 8.106 1.00 11.50 ? 61 PRO J O 1 ATOM 6252 C CB . PRO B 2 61 ? -59.601 -24.003 8.536 1.00 10.90 ? 61 PRO J CB 1 ATOM 6253 C CG . PRO B 2 61 ? -59.734 -24.961 9.666 1.00 10.83 ? 61 PRO J CG 1 ATOM 6254 C CD . PRO B 2 61 ? -58.384 -25.009 10.300 1.00 13.23 ? 61 PRO J CD 1 ATOM 6255 N N . GLN B 2 62 ? -57.890 -22.738 6.130 1.00 9.06 ? 62 GLN J N 1 ATOM 6256 C CA . GLN B 2 62 ? -57.095 -21.802 5.331 1.00 11.29 ? 62 GLN J CA 1 ATOM 6257 C C . GLN B 2 62 ? -57.111 -20.306 5.687 1.00 13.12 ? 62 GLN J C 1 ATOM 6258 O O . GLN B 2 62 ? -56.069 -19.648 5.637 1.00 16.29 ? 62 GLN J O 1 ATOM 6259 C CB . GLN B 2 62 ? -57.394 -21.993 3.847 1.00 9.59 ? 62 GLN J CB 1 ATOM 6260 C CG . GLN B 2 62 ? -56.845 -23.288 3.288 1.00 10.70 ? 62 GLN J CG 1 ATOM 6261 C CD . GLN B 2 62 ? -56.717 -23.239 1.786 1.00 11.97 ? 62 GLN J CD 1 ATOM 6262 O OE1 . GLN B 2 62 ? -57.186 -22.295 1.152 1.00 13.84 ? 62 GLN J OE1 1 ATOM 6263 N NE2 . GLN B 2 62 ? -56.076 -24.248 1.204 1.00 10.13 ? 62 GLN J NE2 1 ATOM 6264 N N . SER B 2 63 ? -58.269 -19.763 6.033 1.00 9.83 ? 63 SER J N 1 ATOM 6265 C CA . SER B 2 63 ? -58.359 -18.332 6.310 1.00 11.88 ? 63 SER J CA 1 ATOM 6266 C C . SER B 2 63 ? -57.782 -17.943 7.671 1.00 15.36 ? 63 SER J C 1 ATOM 6267 O O . SER B 2 63 ? -57.675 -16.758 7.996 1.00 17.03 ? 63 SER J O 1 ATOM 6268 C CB . SER B 2 63 ? -59.810 -17.871 6.219 1.00 17.87 ? 63 SER J CB 1 ATOM 6269 O OG . SER B 2 63 ? -60.648 -18.678 7.030 1.00 21.00 ? 63 SER J OG 1 ATOM 6270 N N . TYR B 2 64 ? -57.407 -18.945 8.458 1.00 16.31 ? 64 TYR J N 1 ATOM 6271 C CA . TYR B 2 64 ? -56.993 -18.730 9.839 1.00 14.76 ? 64 TYR J CA 1 ATOM 6272 C C . TYR B 2 64 ? -55.480 -18.666 9.991 1.00 20.33 ? 64 TYR J C 1 ATOM 6273 O O . TYR B 2 64 ? -54.739 -19.446 9.386 1.00 20.12 ? 64 TYR J O 1 ATOM 6274 C CB . TYR B 2 64 ? -57.589 -19.811 10.738 1.00 12.33 ? 64 TYR J CB 1 ATOM 6275 C CG . TYR B 2 64 ? -59.082 -19.922 10.563 1.00 18.85 ? 64 TYR J CG 1 ATOM 6276 C CD1 . TYR B 2 64 ? -59.630 -20.760 9.597 1.00 17.36 ? 64 TYR J CD1 1 ATOM 6277 C CD2 . TYR B 2 64 ? -59.950 -19.164 11.338 1.00 23.42 ? 64 TYR J CD2 1 ATOM 6278 C CE1 . TYR B 2 64 ? -61.007 -20.851 9.419 1.00 14.33 ? 64 TYR J CE1 1 ATOM 6279 C CE2 . TYR B 2 64 ? -61.329 -19.249 11.167 1.00 20.67 ? 64 TYR J CE2 1 ATOM 6280 C CZ . TYR B 2 64 ? -61.847 -20.094 10.206 1.00 15.25 ? 64 TYR J CZ 1 ATOM 6281 O OH . TYR B 2 64 ? -63.209 -20.181 10.041 1.00 14.57 ? 64 TYR J OH 1 ATOM 6282 N N . ASN B 2 65 ? -55.038 -17.718 10.809 1.00 22.11 ? 65 ASN J N 1 ATOM 6283 C CA . ASN B 2 65 ? -53.627 -17.471 11.039 1.00 16.29 ? 65 ASN J CA 1 ATOM 6284 C C . ASN B 2 65 ? -53.299 -17.751 12.497 1.00 17.65 ? 65 ASN J C 1 ATOM 6285 O O . ASN B 2 65 ? -53.684 -16.983 13.375 1.00 17.10 ? 65 ASN J O 1 ATOM 6286 C CB . ASN B 2 65 ? -53.313 -16.017 10.691 1.00 17.48 ? 65 ASN J CB 1 ATOM 6287 C CG . ASN B 2 65 ? -51.854 -15.676 10.866 1.00 23.21 ? 65 ASN J CG 1 ATOM 6288 O OD1 . ASN B 2 65 ? -51.032 -15.930 9.985 1.00 26.95 ? 65 ASN J OD1 1 ATOM 6289 N ND2 . ASN B 2 65 ? -51.523 -15.078 12.003 1.00 26.97 ? 65 ASN J ND2 1 ATOM 6290 N N . PRO B 2 66 ? -52.605 -18.870 12.766 1.00 18.64 ? 66 PRO J N 1 ATOM 6291 C CA . PRO B 2 66 ? -52.267 -19.284 14.136 1.00 15.97 ? 66 PRO J CA 1 ATOM 6292 C C . PRO B 2 66 ? -51.172 -18.416 14.758 1.00 19.46 ? 66 PRO J C 1 ATOM 6293 O O . PRO B 2 66 ? -50.056 -18.342 14.235 1.00 17.54 ? 66 PRO J O 1 ATOM 6294 C CB . PRO B 2 66 ? -51.758 -20.721 13.960 1.00 14.30 ? 66 PRO J CB 1 ATOM 6295 C CG . PRO B 2 66 ? -52.138 -21.122 12.564 1.00 16.62 ? 66 PRO J CG 1 ATOM 6296 C CD . PRO B 2 66 ? -52.167 -19.859 11.770 1.00 16.64 ? 66 PRO J CD 1 ATOM 6297 N N . ILE B 2 67 ? -51.499 -17.770 15.873 1.00 18.70 ? 67 ILE J N 1 ATOM 6298 C CA . ILE B 2 67 ? -50.551 -16.932 16.595 1.00 15.80 ? 67 ILE J CA 1 ATOM 6299 C C . ILE B 2 67 ? -50.847 -17.015 18.083 1.00 17.47 ? 67 ILE J C 1 ATOM 6300 O O . ILE B 2 67 ? -51.988 -16.833 18.505 1.00 17.46 ? 67 ILE J O 1 ATOM 6301 C CB . ILE B 2 67 ? -50.600 -15.476 16.114 1.00 16.86 ? 67 ILE J CB 1 ATOM 6302 C CG1 . ILE B 2 67 ? -49.615 -15.281 14.962 1.00 16.54 ? 67 ILE J CG1 1 ATOM 6303 C CG2 . ILE B 2 67 ? -50.278 -14.516 17.246 1.00 19.27 ? 67 ILE J CG2 1 ATOM 6304 C CD1 . ILE B 2 67 ? -49.577 -13.869 14.420 1.00 26.66 ? 67 ILE J CD1 1 ATOM 6305 N N . CYS B 2 68 ? -49.814 -17.304 18.869 1.00 18.49 ? 68 CYS J N 1 ATOM 6306 C CA . CYS B 2 68 ? -49.983 -17.626 20.282 1.00 18.88 ? 68 CYS J CA 1 ATOM 6307 C C . CYS B 2 68 ? -50.257 -16.396 21.124 1.00 20.19 ? 68 CYS J C 1 ATOM 6308 O O . CYS B 2 68 ? -49.557 -15.391 21.013 1.00 20.79 ? 68 CYS J O 1 ATOM 6309 C CB . CYS B 2 68 ? -48.747 -18.351 20.798 1.00 17.68 ? 68 CYS J CB 1 ATOM 6310 S SG . CYS B 2 68 ? -48.254 -19.711 19.728 1.00 19.04 ? 68 CYS J SG 1 ATOM 6311 N N . LYS B 2 69 ? -51.281 -16.475 21.967 1.00 16.63 ? 69 LYS J N 1 ATOM 6312 C CA . LYS B 2 69 ? -51.657 -15.326 22.771 1.00 18.09 ? 69 LYS J CA 1 ATOM 6313 C C . LYS B 2 69 ? -51.358 -15.488 24.246 1.00 24.36 ? 69 LYS J C 1 ATOM 6314 O O . LYS B 2 69 ? -51.563 -16.550 24.831 1.00 25.91 ? 69 LYS J O 1 ATOM 6315 C CB . LYS B 2 69 ? -53.127 -14.966 22.570 1.00 21.63 ? 69 LYS J CB 1 ATOM 6316 C CG . LYS B 2 69 ? -53.379 -14.148 21.316 1.00 30.86 ? 69 LYS J CG 1 ATOM 6317 C CD . LYS B 2 69 ? -52.230 -13.178 21.056 1.00 32.85 ? 69 LYS J CD 1 ATOM 6318 C CE . LYS B 2 69 ? -52.321 -12.573 19.665 1.00 32.83 ? 69 LYS J CE 1 ATOM 6319 N NZ . LYS B 2 69 ? -50.983 -12.149 19.154 1.00 31.44 1 69 LYS J NZ 1 ATOM 6320 N N . GLN B 2 70 ? -50.868 -14.408 24.838 1.00 23.50 ? 70 GLN J N 1 ATOM 6321 C CA . GLN B 2 70 ? -50.634 -14.356 26.265 1.00 23.81 ? 70 GLN J CA 1 ATOM 6322 C C . GLN B 2 70 ? -51.901 -13.864 26.958 1.00 23.65 ? 70 GLN J C 1 ATOM 6323 O O . GLN B 2 70 ? -52.290 -12.708 26.812 1.00 24.08 ? 70 GLN J O 1 ATOM 6324 C CB . GLN B 2 70 ? -49.459 -13.423 26.558 1.00 28.03 ? 70 GLN J CB 1 ATOM 6325 C CG . GLN B 2 70 ? -49.068 -13.334 28.021 1.00 29.66 ? 70 GLN J CG 1 ATOM 6326 C CD . GLN B 2 70 ? -48.510 -14.627 28.568 1.00 27.38 ? 70 GLN J CD 1 ATOM 6327 O OE1 . GLN B 2 70 ? -47.371 -14.991 28.281 1.00 26.72 ? 70 GLN J OE1 1 ATOM 6328 N NE2 . GLN B 2 70 ? -49.308 -15.327 29.367 1.00 23.84 ? 70 GLN J NE2 1 ATOM 6329 N N . HIS B 2 71 ? -52.553 -14.751 27.698 1.00 24.49 ? 71 HIS J N 1 ATOM 6330 C CA . HIS B 2 71 ? -53.754 -14.382 28.438 1.00 29.62 ? 71 HIS J CA 1 ATOM 6331 C C . HIS B 2 71 ? -53.451 -14.067 29.908 1.00 34.32 ? 71 HIS J C 1 ATOM 6332 O O . HIS B 2 71 ? -52.553 -14.657 30.513 1.00 33.70 ? 71 HIS J O 1 ATOM 6333 C CB . HIS B 2 71 ? -54.807 -15.491 28.331 1.00 34.33 ? 71 HIS J CB 1 ATOM 6334 C CG . HIS B 2 71 ? -55.585 -15.467 27.051 1.00 35.43 ? 71 HIS J CG 1 ATOM 6335 N ND1 . HIS B 2 71 ? -56.942 -15.232 27.010 1.00 38.88 ? 71 HIS J ND1 1 ATOM 6336 C CD2 . HIS B 2 71 ? -55.195 -15.644 25.766 1.00 33.45 ? 71 HIS J CD2 1 ATOM 6337 C CE1 . HIS B 2 71 ? -57.356 -15.264 25.755 1.00 37.91 ? 71 HIS J CE1 1 ATOM 6338 N NE2 . HIS B 2 71 ? -56.316 -15.513 24.980 1.00 34.53 ? 71 HIS J NE2 1 ATOM 6339 N N . TYR B 2 72 ? -54.206 -13.133 30.478 1.00 32.44 ? 72 TYR J N 1 ATOM 6340 C CA . TYR B 2 72 ? -54.008 -12.733 31.867 1.00 32.51 ? 72 TYR J CA 1 ATOM 6341 C C . TYR B 2 72 ? -55.234 -13.000 32.725 1.00 36.76 ? 72 TYR J C 1 ATOM 6342 O O . TYR B 2 72 ? -56.227 -13.551 32.257 1.00 42.03 ? 72 TYR J O 1 ATOM 6343 C CB . TYR B 2 72 ? -53.687 -11.245 31.955 1.00 36.04 ? 72 TYR J CB 1 ATOM 6344 C CG . TYR B 2 72 ? -52.443 -10.822 31.221 1.00 37.41 ? 72 TYR J CG 1 ATOM 6345 C CD1 . TYR B 2 72 ? -51.422 -11.719 30.967 1.00 33.94 ? 72 TYR J CD1 1 ATOM 6346 C CD2 . TYR B 2 72 ? -52.287 -9.514 30.790 1.00 47.82 ? 72 TYR J CD2 1 ATOM 6347 C CE1 . TYR B 2 72 ? -50.288 -11.326 30.303 1.00 35.22 ? 72 TYR J CE1 1 ATOM 6348 C CE2 . TYR B 2 72 ? -51.153 -9.114 30.120 1.00 41.54 ? 72 TYR J CE2 1 ATOM 6349 C CZ . TYR B 2 72 ? -50.159 -10.025 29.877 1.00 38.09 ? 72 TYR J CZ 1 ATOM 6350 O OH . TYR B 2 72 ? -49.026 -9.629 29.210 1.00 56.01 ? 72 TYR J OH 1 ATOM 6351 N N . THR B 2 73 ? -55.145 -12.589 33.985 1.00 34.80 ? 73 THR J N 1 ATOM 6352 C CA . THR B 2 73 ? -56.253 -12.662 34.930 1.00 44.17 ? 73 THR J CA 1 ATOM 6353 C C . THR B 2 73 ? -56.105 -11.536 35.941 1.00 49.96 ? 73 THR J C 1 ATOM 6354 O O . THR B 2 73 ? -55.038 -10.926 36.038 1.00 48.69 ? 73 THR J O 1 ATOM 6355 C CB . THR B 2 73 ? -56.268 -13.991 35.716 1.00 47.81 ? 73 THR J CB 1 ATOM 6356 O OG1 . THR B 2 73 ? -54.930 -14.342 36.091 1.00 44.32 ? 73 THR J OG1 1 ATOM 6357 C CG2 . THR B 2 73 ? -56.887 -15.118 34.894 1.00 45.38 ? 73 THR J CG2 1 ATOM 6358 N N . GLN B 2 74 ? -57.174 -11.275 36.693 1.00 47.89 ? 74 GLN J N 1 ATOM 6359 C CA . GLN B 2 74 ? -57.168 -10.270 37.755 1.00 41.45 ? 74 GLN J CA 1 ATOM 6360 C C . GLN B 2 74 ? -56.697 -8.909 37.246 1.00 32.90 ? 74 GLN J C 1 ATOM 6361 O O . GLN B 2 74 ? -57.190 -7.868 37.672 1.00 23.75 ? 74 GLN J O 1 ATOM 6362 C CB . GLN B 2 74 ? -56.292 -10.739 38.924 1.00 55.59 ? 74 GLN J CB 1 ATOM 6363 C CG . GLN B 2 74 ? -56.230 -9.775 40.103 1.00 58.38 ? 74 GLN J CG 1 ATOM 6364 C CD . GLN B 2 74 ? -55.381 -10.301 41.249 1.00 51.56 ? 74 GLN J CD 1 ATOM 6365 O OE1 . GLN B 2 74 ? -55.443 -11.482 41.594 1.00 53.16 ? 74 GLN J OE1 1 ATOM 6366 N NE2 . GLN B 2 74 ? -54.579 -9.423 41.840 1.00 54.01 ? 74 GLN J NE2 1 ATOM 6367 N N . LYS B 2 94 ? -51.836 -7.825 37.018 1.00 34.65 ? 94 LYS J N 1 ATOM 6368 C CA . LYS B 2 94 ? -51.561 -8.433 35.720 1.00 39.64 ? 94 LYS J CA 1 ATOM 6369 C C . LYS B 2 94 ? -50.788 -9.740 35.867 1.00 40.10 ? 94 LYS J C 1 ATOM 6370 O O . LYS B 2 94 ? -49.560 -9.765 35.806 1.00 42.44 ? 94 LYS J O 1 ATOM 6371 C CB . LYS B 2 94 ? -50.808 -7.460 34.802 1.00 42.72 ? 94 LYS J CB 1 ATOM 6372 C CG . LYS B 2 94 ? -49.637 -6.732 35.461 1.00 52.61 ? 94 LYS J CG 1 ATOM 6373 C CD . LYS B 2 94 ? -48.895 -5.848 34.466 1.00 55.92 ? 94 LYS J CD 1 ATOM 6374 C CE . LYS B 2 94 ? -47.703 -5.162 35.117 1.00 66.86 ? 94 LYS J CE 1 ATOM 6375 N NZ . LYS B 2 94 ? -48.108 -4.319 36.278 1.00 54.25 1 94 LYS J NZ 1 ATOM 6376 N N . ILE B 2 95 ? -51.522 -10.829 36.058 1.00 36.84 ? 95 ILE J N 1 ATOM 6377 C CA . ILE B 2 95 ? -50.918 -12.141 36.230 1.00 31.11 ? 95 ILE J CA 1 ATOM 6378 C C . ILE B 2 95 ? -51.119 -13.006 34.988 1.00 29.79 ? 95 ILE J C 1 ATOM 6379 O O . ILE B 2 95 ? -52.237 -13.427 34.694 1.00 37.81 ? 95 ILE J O 1 ATOM 6380 C CB . ILE B 2 95 ? -51.480 -12.837 37.491 1.00 37.16 ? 95 ILE J CB 1 ATOM 6381 C CG1 . ILE B 2 95 ? -50.785 -12.295 38.741 1.00 31.09 ? 95 ILE J CG1 1 ATOM 6382 C CG2 . ILE B 2 95 ? -51.318 -14.347 37.420 1.00 38.18 ? 95 ILE J CG2 1 ATOM 6383 C CD1 . ILE B 2 95 ? -51.533 -12.573 40.020 1.00 31.81 ? 95 ILE J CD1 1 ATOM 6384 N N . PRO B 2 96 ? -50.036 -13.229 34.227 1.00 26.00 ? 96 PRO J N 1 ATOM 6385 C CA . PRO B 2 96 ? -50.022 -14.177 33.112 1.00 30.66 ? 96 PRO J CA 1 ATOM 6386 C C . PRO B 2 96 ? -50.522 -15.528 33.575 1.00 34.67 ? 96 PRO J C 1 ATOM 6387 O O . PRO B 2 96 ? -49.814 -16.215 34.308 1.00 37.43 ? 96 PRO J O 1 ATOM 6388 C CB . PRO B 2 96 ? -48.539 -14.268 32.766 1.00 32.34 ? 96 PRO J CB 1 ATOM 6389 C CG . PRO B 2 96 ? -48.025 -12.912 33.072 1.00 34.15 ? 96 PRO J CG 1 ATOM 6390 C CD . PRO B 2 96 ? -48.787 -12.453 34.293 1.00 34.00 ? 96 PRO J CD 1 ATOM 6391 N N . SER B 2 97 ? -51.728 -15.895 33.155 1.00 32.15 ? 97 SER J N 1 ATOM 6392 C CA . SER B 2 97 ? -52.378 -17.101 33.648 1.00 32.12 ? 97 SER J CA 1 ATOM 6393 C C . SER B 2 97 ? -52.391 -18.200 32.600 1.00 33.66 ? 97 SER J C 1 ATOM 6394 O O . SER B 2 97 ? -52.511 -19.384 32.924 1.00 31.94 ? 97 SER J O 1 ATOM 6395 C CB . SER B 2 97 ? -53.812 -16.783 34.058 1.00 34.76 ? 97 SER J CB 1 ATOM 6396 O OG . SER B 2 97 ? -54.548 -16.281 32.955 1.00 33.79 ? 97 SER J OG 1 ATOM 6397 N N . CYS B 2 98 ? -52.268 -17.808 31.339 1.00 33.47 ? 98 CYS J N 1 ATOM 6398 C CA . CYS B 2 98 ? -52.425 -18.767 30.260 1.00 31.79 ? 98 CYS J CA 1 ATOM 6399 C C . CYS B 2 98 ? -51.809 -18.327 28.937 1.00 30.50 ? 98 CYS J C 1 ATOM 6400 O O . CYS B 2 98 ? -51.640 -17.137 28.671 1.00 30.26 ? 98 CYS J O 1 ATOM 6401 C CB . CYS B 2 98 ? -53.905 -19.070 30.059 1.00 31.19 ? 98 CYS J CB 1 ATOM 6402 S SG . CYS B 2 98 ? -54.185 -20.300 28.801 1.00 53.98 ? 98 CYS J SG 1 ATOM 6403 N N . CYS B 2 99 ? -51.481 -19.306 28.105 1.00 27.15 ? 99 CYS J N 1 ATOM 6404 C CA . CYS B 2 99 ? -50.927 -19.032 26.791 1.00 25.50 ? 99 CYS J CA 1 ATOM 6405 C C . CYS B 2 99 ? -51.529 -19.977 25.765 1.00 29.70 ? 99 CYS J C 1 ATOM 6406 O O . CYS B 2 99 ? -51.153 -21.151 25.685 1.00 28.57 ? 99 CYS J O 1 ATOM 6407 C CB . CYS B 2 99 ? -49.413 -19.179 26.812 1.00 27.00 ? 99 CYS J CB 1 ATOM 6408 S SG . CYS B 2 99 ? -48.659 -19.098 25.188 1.00 28.46 ? 99 CYS J SG 1 ATOM 6409 N N . LYS B 2 100 ? -52.473 -19.460 24.984 1.00 29.76 ? 100 LYS J N 1 ATOM 6410 C CA . LYS B 2 100 ? -53.163 -20.266 23.986 1.00 22.43 ? 100 LYS J CA 1 ATOM 6411 C C . LYS B 2 100 ? -53.097 -19.681 22.573 1.00 22.87 ? 100 LYS J C 1 ATOM 6412 O O . LYS B 2 100 ? -52.742 -18.513 22.367 1.00 18.72 ? 100 LYS J O 1 ATOM 6413 C CB . LYS B 2 100 ? -54.612 -20.536 24.404 1.00 18.85 ? 100 LYS J CB 1 ATOM 6414 C CG . LYS B 2 100 ? -55.398 -19.314 24.838 1.00 21.00 ? 100 LYS J CG 1 ATOM 6415 C CD . LYS B 2 100 ? -56.796 -19.733 25.264 1.00 32.39 ? 100 LYS J CD 1 ATOM 6416 C CE . LYS B 2 100 ? -57.763 -18.561 25.327 1.00 35.27 ? 100 LYS J CE 1 ATOM 6417 N NZ . LYS B 2 100 ? -59.188 -19.012 25.294 1.00 26.45 1 100 LYS J NZ 1 ATOM 6418 N N . CYS B 2 101 ? -53.442 -20.524 21.607 1.00 22.96 ? 101 CYS J N 1 ATOM 6419 C CA . CYS B 2 101 ? -53.319 -20.199 20.197 1.00 15.53 ? 101 CYS J CA 1 ATOM 6420 C C . CYS B 2 101 ? -54.597 -19.556 19.680 1.00 20.45 ? 101 CYS J C 1 ATOM 6421 O O . CYS B 2 101 ? -55.685 -20.134 19.773 1.00 19.40 ? 101 CYS J O 1 ATOM 6422 C CB . CYS B 2 101 ? -53.023 -21.472 19.411 1.00 12.15 ? 101 CYS J CB 1 ATOM 6423 S SG . CYS B 2 101 ? -52.674 -21.199 17.691 1.00 15.31 ? 101 CYS J SG 1 ATOM 6424 N N . ALA B 2 102 ? -54.466 -18.351 19.142 1.00 18.67 ? 102 ALA J N 1 ATOM 6425 C CA . ALA B 2 102 ? -55.617 -17.642 18.613 1.00 15.51 ? 102 ALA J CA 1 ATOM 6426 C C . ALA B 2 102 ? -55.598 -17.672 17.098 1.00 16.46 ? 102 ALA J C 1 ATOM 6427 O O . ALA B 2 102 ? -54.791 -16.999 16.466 1.00 20.07 ? 102 ALA J O 1 ATOM 6428 C CB . ALA B 2 102 ? -55.638 -16.212 19.111 1.00 17.49 ? 102 ALA J CB 1 ATOM 6429 N N . LEU B 2 103 ? -56.482 -18.467 16.513 1.00 17.72 ? 103 LEU J N 1 ATOM 6430 C CA . LEU B 2 103 ? -56.662 -18.436 15.074 1.00 17.51 ? 103 LEU J CA 1 ATOM 6431 C C . LEU B 2 103 ? -57.301 -17.108 14.703 1.00 17.62 ? 103 LEU J C 1 ATOM 6432 O O . LEU B 2 103 ? -58.499 -16.905 14.902 1.00 16.45 ? 103 LEU J O 1 ATOM 6433 C CB . LEU B 2 103 ? -57.528 -19.606 14.616 1.00 16.13 ? 103 LEU J CB 1 ATOM 6434 C CG . LEU B 2 103 ? -56.990 -20.983 15.007 1.00 14.83 ? 103 LEU J CG 1 ATOM 6435 C CD1 . LEU B 2 103 ? -57.935 -22.055 14.541 1.00 14.82 ? 103 LEU J CD1 1 ATOM 6436 C CD2 . LEU B 2 103 ? -55.605 -21.220 14.425 1.00 14.85 ? 103 LEU J CD2 1 ATOM 6437 N N . LYS B 2 104 ? -56.485 -16.196 14.186 1.00 18.56 ? 104 LYS J N 1 ATOM 6438 C CA . LYS B 2 104 ? -56.959 -14.862 13.841 1.00 22.35 ? 104 LYS J CA 1 ATOM 6439 C C . LYS B 2 104 ? -57.252 -14.700 12.358 1.00 24.27 ? 104 LYS J C 1 ATOM 6440 O O . LYS B 2 104 ? -56.416 -14.983 11.497 1.00 20.28 ? 104 LYS J O 1 ATOM 6441 C CB . LYS B 2 104 ? -55.982 -13.785 14.320 1.00 27.55 ? 104 LYS J CB 1 ATOM 6442 C CG . LYS B 2 104 ? -54.518 -14.190 14.246 1.00 28.06 ? 104 LYS J CG 1 ATOM 6443 C CD . LYS B 2 104 ? -53.634 -13.176 14.944 1.00 26.78 ? 104 LYS J CD 1 ATOM 6444 C CE . LYS B 2 104 ? -54.122 -12.909 16.359 1.00 31.60 ? 104 LYS J CE 1 ATOM 6445 N NZ . LYS B 2 104 ? -53.443 -11.729 16.964 1.00 43.23 1 104 LYS J NZ 1 ATOM 6446 N N . THR B 2 105 ? -58.464 -14.236 12.084 1.00 31.32 ? 105 THR J N 1 ATOM 6447 C CA . THR B 2 105 ? -58.945 -14.031 10.732 1.00 31.95 ? 105 THR J CA 1 ATOM 6448 C C . THR B 2 105 ? -58.931 -12.558 10.394 1.00 34.86 ? 105 THR J C 1 ATOM 6449 O O . THR B 2 105 ? -59.783 -11.808 10.866 1.00 34.49 ? 105 THR J O 1 ATOM 6450 C CB . THR B 2 105 ? -60.396 -14.485 10.615 1.00 33.58 ? 105 THR J CB 1 ATOM 6451 O OG1 . THR B 2 105 ? -61.059 -14.245 11.862 1.00 31.98 ? 105 THR J OG1 1 ATOM 6452 C CG2 . THR B 2 105 ? -60.469 -15.961 10.291 1.00 30.05 ? 105 THR J CG2 1 ATOM 6453 N N . GLY B 2 106 ? -57.963 -12.137 9.588 1.00 39.50 ? 106 GLY J N 1 ATOM 6454 C CA . GLY B 2 106 ? -57.990 -10.791 9.050 1.00 44.57 ? 106 GLY J CA 1 ATOM 6455 C C . GLY B 2 106 ? -59.112 -10.721 8.028 1.00 61.02 ? 106 GLY J C 1 ATOM 6456 O O . GLY B 2 106 ? -59.556 -11.757 7.524 1.00 56.31 ? 106 GLY J O 1 ATOM 6457 N N . LEU B 2 107 ? -59.585 -9.514 7.729 1.00 58.63 ? 107 LEU J N 1 ATOM 6458 C CA . LEU B 2 107 ? -60.581 -9.333 6.673 1.00 54.99 ? 107 LEU J CA 1 ATOM 6459 C C . LEU B 2 107 ? -59.890 -9.074 5.330 1.00 49.05 ? 107 LEU J C 1 ATOM 6460 O O . LEU B 2 107 ? -60.432 -8.398 4.457 1.00 53.83 ? 107 LEU J O 1 ATOM 6461 C CB . LEU B 2 107 ? -61.560 -8.198 7.013 1.00 58.81 ? 107 LEU J CB 1 ATOM 6462 C CG . LEU B 2 107 ? -63.033 -8.558 7.257 1.00 43.58 ? 107 LEU J CG 1 ATOM 6463 C CD1 . LEU B 2 107 ? -63.894 -7.301 7.400 1.00 28.39 ? 107 LEU J CD1 1 ATOM 6464 C CD2 . LEU B 2 107 ? -63.567 -9.464 6.151 1.00 25.27 ? 107 LEU J CD2 1 ATOM 6465 N N . GLU B 2 108 ? -58.683 -9.611 5.185 1.00 45.61 ? 108 GLU J N 1 ATOM 6466 C CA . GLU B 2 108 ? -57.922 -9.513 3.946 1.00 49.57 ? 108 GLU J CA 1 ATOM 6467 C C . GLU B 2 108 ? -57.317 -10.884 3.629 1.00 56.10 ? 108 GLU J C 1 ATOM 6468 O O . GLU B 2 108 ? -57.177 -11.730 4.518 1.00 51.01 ? 108 GLU J O 1 ATOM 6469 C CB . GLU B 2 108 ? -56.796 -8.477 4.078 1.00 61.60 ? 108 GLU J CB 1 ATOM 6470 C CG . GLU B 2 108 ? -57.083 -7.300 5.018 1.00 60.93 ? 108 GLU J CG 1 ATOM 6471 C CD . GLU B 2 108 ? -57.748 -6.120 4.326 1.00 62.28 ? 108 GLU J CD 1 ATOM 6472 O OE1 . GLU B 2 108 ? -57.534 -5.940 3.105 1.00 70.03 ? 108 GLU J OE1 1 ATOM 6473 O OE2 . GLU B 2 108 ? -58.482 -5.368 5.007 1.00 49.68 1 108 GLU J OE2 1 ATOM 6474 N N . HIS B 2 109 ? -56.951 -11.102 2.369 1.00 57.58 ? 109 HIS J N 1 ATOM 6475 C CA . HIS B 2 109 ? -56.302 -12.351 1.973 1.00 51.02 ? 109 HIS J CA 1 ATOM 6476 C C . HIS B 2 109 ? -54.775 -12.261 2.082 1.00 47.63 ? 109 HIS J C 1 ATOM 6477 O O . HIS B 2 109 ? -54.132 -13.092 2.730 1.00 30.48 ? 109 HIS J O 1 ATOM 6478 C CB . HIS B 2 109 ? -56.716 -12.751 0.553 1.00 28.66 ? 109 HIS J CB 1 ATOM 6479 C CG . HIS B 2 109 ? -57.299 -14.128 0.463 1.00 37.57 ? 109 HIS J CG 1 ATOM 6480 N ND1 . HIS B 2 109 ? -57.178 -14.919 -0.660 1.00 34.80 ? 109 HIS J ND1 1 ATOM 6481 C CD2 . HIS B 2 109 ? -58.007 -14.856 1.361 1.00 35.08 ? 109 HIS J CD2 1 ATOM 6482 C CE1 . HIS B 2 109 ? -57.785 -16.075 -0.451 1.00 25.81 ? 109 HIS J CE1 1 ATOM 6483 N NE2 . HIS B 2 109 ? -58.298 -16.062 0.767 1.00 26.06 ? 109 HIS J NE2 1 ATOM 6484 N N . VAL C 2 1 ? -58.188 -3.432 13.197 1.00 65.18 ? 1 VAL K N 1 ATOM 6485 C CA . VAL C 2 1 ? -58.954 -3.084 12.004 1.00 70.02 ? 1 VAL K CA 1 ATOM 6486 C C . VAL C 2 1 ? -60.405 -3.563 12.106 1.00 60.32 ? 1 VAL K C 1 ATOM 6487 O O . VAL C 2 1 ? -60.831 -4.070 13.145 1.00 52.29 ? 1 VAL K O 1 ATOM 6488 C CB . VAL C 2 1 ? -58.293 -3.649 10.721 1.00 61.66 ? 1 VAL K CB 1 ATOM 6489 C CG1 . VAL C 2 1 ? -57.034 -2.869 10.380 1.00 44.81 ? 1 VAL K CG1 1 ATOM 6490 C CG2 . VAL C 2 1 ? -57.973 -5.125 10.889 1.00 62.38 ? 1 VAL K CG2 1 ATOM 6491 N N . GLY C 2 2 ? -61.163 -3.392 11.029 1.00 53.90 ? 2 GLY K N 1 ATOM 6492 C CA . GLY C 2 2 ? -62.544 -3.837 11.002 1.00 72.15 ? 2 GLY K CA 1 ATOM 6493 C C . GLY C 2 2 ? -62.648 -5.349 10.907 1.00 76.79 ? 2 GLY K C 1 ATOM 6494 O O . GLY C 2 2 ? -61.890 -5.983 10.167 1.00 68.20 ? 2 GLY K O 1 ATOM 6495 N N . GLY C 2 3 ? -63.587 -5.924 11.658 1.00 72.83 ? 3 GLY K N 1 ATOM 6496 C CA . GLY C 2 3 ? -63.801 -7.362 11.674 1.00 51.99 ? 3 GLY K CA 1 ATOM 6497 C C . GLY C 2 3 ? -62.554 -8.171 11.986 1.00 54.87 ? 3 GLY K C 1 ATOM 6498 O O . GLY C 2 3 ? -62.315 -9.203 11.362 1.00 55.98 ? 3 GLY K O 1 ATOM 6499 N N . SER C 2 4 ? -61.763 -7.701 12.950 1.00 64.68 ? 4 SER K N 1 ATOM 6500 C CA . SER C 2 4 ? -60.497 -8.343 13.316 1.00 57.55 ? 4 SER K CA 1 ATOM 6501 C C . SER C 2 4 ? -60.678 -9.399 14.407 1.00 53.67 ? 4 SER K C 1 ATOM 6502 O O . SER C 2 4 ? -59.893 -9.477 15.356 1.00 48.32 ? 4 SER K O 1 ATOM 6503 C CB . SER C 2 4 ? -59.476 -7.293 13.770 1.00 56.81 ? 4 SER K CB 1 ATOM 6504 O OG . SER C 2 4 ? -59.943 -6.573 14.900 1.00 49.11 ? 4 SER K OG 1 ATOM 6505 N N . ASP C 2 5 ? -61.718 -10.211 14.258 1.00 47.32 ? 5 ASP K N 1 ATOM 6506 C CA . ASP C 2 5 ? -62.056 -11.231 15.240 1.00 39.54 ? 5 ASP K CA 1 ATOM 6507 C C . ASP C 2 5 ? -61.052 -12.375 15.219 1.00 27.75 ? 5 ASP K C 1 ATOM 6508 O O . ASP C 2 5 ? -60.571 -12.777 14.161 1.00 25.71 ? 5 ASP K O 1 ATOM 6509 C CB . ASP C 2 5 ? -63.469 -11.758 14.972 1.00 44.02 ? 5 ASP K CB 1 ATOM 6510 C CG . ASP C 2 5 ? -63.872 -12.873 15.920 1.00 40.99 ? 5 ASP K CG 1 ATOM 6511 O OD1 . ASP C 2 5 ? -63.474 -12.819 17.108 1.00 34.03 ? 5 ASP K OD1 1 ATOM 6512 O OD2 . ASP C 2 5 ? -64.591 -13.799 15.472 1.00 33.00 1 5 ASP K OD2 1 ATOM 6513 N N . GLU C 2 6 ? -60.740 -12.893 16.400 1.00 24.67 ? 6 GLU K N 1 ATOM 6514 C CA . GLU C 2 6 ? -59.822 -14.015 16.526 1.00 27.81 ? 6 GLU K CA 1 ATOM 6515 C C . GLU C 2 6 ? -60.551 -15.221 17.090 1.00 25.80 ? 6 GLU K C 1 ATOM 6516 O O . GLU C 2 6 ? -61.343 -15.094 18.023 1.00 34.40 ? 6 GLU K O 1 ATOM 6517 C CB . GLU C 2 6 ? -58.648 -13.643 17.433 1.00 38.27 ? 6 GLU K CB 1 ATOM 6518 C CG . GLU C 2 6 ? -59.054 -13.104 18.799 1.00 34.62 ? 6 GLU K CG 1 ATOM 6519 C CD . GLU C 2 6 ? -57.861 -12.707 19.640 1.00 36.02 ? 6 GLU K CD 1 ATOM 6520 O OE1 . GLU C 2 6 ? -57.920 -11.639 20.285 1.00 39.81 ? 6 GLU K OE1 1 ATOM 6521 O OE2 . GLU C 2 6 ? -56.864 -13.463 19.660 1.00 34.14 1 6 GLU K OE2 1 ATOM 6522 N N . ARG C 2 7 ? -60.283 -16.396 16.535 1.00 18.34 ? 7 ARG K N 1 ATOM 6523 C CA . ARG C 2 7 ? -61.031 -17.579 16.936 1.00 20.04 ? 7 ARG K CA 1 ATOM 6524 C C . ARG C 2 7 ? -60.173 -18.562 17.717 1.00 17.05 ? 7 ARG K C 1 ATOM 6525 O O . ARG C 2 7 ? -59.160 -19.042 17.222 1.00 18.35 ? 7 ARG K O 1 ATOM 6526 C CB . ARG C 2 7 ? -61.631 -18.268 15.712 1.00 22.93 ? 7 ARG K CB 1 ATOM 6527 C CG . ARG C 2 7 ? -62.254 -17.311 14.703 1.00 25.96 ? 7 ARG K CG 1 ATOM 6528 C CD . ARG C 2 7 ? -63.577 -16.755 15.189 1.00 26.50 ? 7 ARG K CD 1 ATOM 6529 N NE . ARG C 2 7 ? -64.537 -17.820 15.450 1.00 23.58 ? 7 ARG K NE 1 ATOM 6530 C CZ . ARG C 2 7 ? -65.244 -18.433 14.508 1.00 20.48 ? 7 ARG K CZ 1 ATOM 6531 N NH1 . ARG C 2 7 ? -66.094 -19.395 14.840 1.00 20.81 1 7 ARG K NH1 1 ATOM 6532 N NH2 . ARG C 2 7 ? -65.097 -18.087 13.235 1.00 19.14 ? 7 ARG K NH2 1 ATOM 6533 N N . PHE C 2 8 ? -60.595 -18.860 18.939 1.00 16.83 ? 8 PHE K N 1 ATOM 6534 C CA . PHE C 2 8 ? -59.903 -19.822 19.785 1.00 15.57 ? 8 PHE K CA 1 ATOM 6535 C C . PHE C 2 8 ? -60.450 -21.232 19.583 1.00 15.48 ? 8 PHE K C 1 ATOM 6536 O O . PHE C 2 8 ? -61.600 -21.408 19.197 1.00 19.02 ? 8 PHE K O 1 ATOM 6537 C CB . PHE C 2 8 ? -60.009 -19.400 21.250 1.00 17.45 ? 8 PHE K CB 1 ATOM 6538 C CG . PHE C 2 8 ? -59.385 -18.069 21.530 1.00 21.58 ? 8 PHE K CG 1 ATOM 6539 C CD1 . PHE C 2 8 ? -58.022 -17.967 21.779 1.00 27.42 ? 8 PHE K CD1 1 ATOM 6540 C CD2 . PHE C 2 8 ? -60.148 -16.916 21.516 1.00 20.99 ? 8 PHE K CD2 1 ATOM 6541 C CE1 . PHE C 2 8 ? -57.433 -16.739 22.025 1.00 26.17 ? 8 PHE K CE1 1 ATOM 6542 C CE2 . PHE C 2 8 ? -59.568 -15.684 21.761 1.00 32.67 ? 8 PHE K CE2 1 ATOM 6543 C CZ . PHE C 2 8 ? -58.206 -15.596 22.017 1.00 32.34 ? 8 PHE K CZ 1 ATOM 6544 N N . LEU C 2 9 ? -59.621 -22.236 19.837 1.00 16.62 ? 9 LEU K N 1 ATOM 6545 C CA . LEU C 2 9 ? -60.015 -23.623 19.604 1.00 17.77 ? 9 LEU K CA 1 ATOM 6546 C C . LEU C 2 9 ? -61.044 -24.114 20.620 1.00 18.31 ? 9 LEU K C 1 ATOM 6547 O O . LEU C 2 9 ? -61.794 -25.051 20.350 1.00 17.72 ? 9 LEU K O 1 ATOM 6548 C CB . LEU C 2 9 ? -58.790 -24.548 19.620 1.00 17.76 ? 9 LEU K CB 1 ATOM 6549 C CG . LEU C 2 9 ? -57.867 -24.591 18.401 1.00 8.94 ? 9 LEU K CG 1 ATOM 6550 C CD1 . LEU C 2 9 ? -56.994 -23.348 18.322 1.00 8.48 ? 9 LEU K CD1 1 ATOM 6551 C CD2 . LEU C 2 9 ? -57.035 -25.863 18.420 1.00 5.98 ? 9 LEU K CD2 1 ATOM 6552 N N . CYS C 2 10 ? -61.064 -23.482 21.789 1.00 20.70 ? 10 CYS K N 1 ATOM 6553 C CA . CYS C 2 10 ? -61.955 -23.880 22.875 1.00 25.43 ? 10 CYS K CA 1 ATOM 6554 C C . CYS C 2 10 ? -62.716 -22.689 23.430 1.00 27.96 ? 10 CYS K C 1 ATOM 6555 O O . CYS C 2 10 ? -62.111 -21.721 23.894 1.00 33.50 ? 10 CYS K O 1 ATOM 6556 C CB . CYS C 2 10 ? -61.163 -24.532 24.007 1.00 18.51 ? 10 CYS K CB 1 ATOM 6557 S SG . CYS C 2 10 ? -60.847 -26.265 23.757 1.00 15.83 ? 10 CYS K SG 1 ATOM 6558 N N . ARG C 2 11 ? -64.041 -22.755 23.398 1.00 26.23 ? 11 ARG K N 1 ATOM 6559 C CA . ARG C 2 11 ? -64.816 -21.635 23.908 1.00 43.87 ? 11 ARG K CA 1 ATOM 6560 C C . ARG C 2 11 ? -64.894 -21.703 25.423 1.00 37.25 ? 11 ARG K C 1 ATOM 6561 O O . ARG C 2 11 ? -64.872 -22.783 26.016 1.00 27.45 ? 11 ARG K O 1 ATOM 6562 C CB . ARG C 2 11 ? -66.210 -21.539 23.271 1.00 46.16 ? 11 ARG K CB 1 ATOM 6563 C CG . ARG C 2 11 ? -67.154 -22.670 23.619 1.00 51.62 ? 11 ARG K CG 1 ATOM 6564 C CD . ARG C 2 11 ? -68.604 -22.221 23.520 1.00 49.91 ? 11 ARG K CD 1 ATOM 6565 N NE . ARG C 2 11 ? -68.950 -21.742 22.186 1.00 57.22 ? 11 ARG K NE 1 ATOM 6566 C CZ . ARG C 2 11 ? -69.333 -22.532 21.189 1.00 55.49 ? 11 ARG K CZ 1 ATOM 6567 N NH1 . ARG C 2 11 ? -69.636 -22.014 20.006 1.00 47.62 1 11 ARG K NH1 1 ATOM 6568 N NH2 . ARG C 2 11 ? -69.410 -23.843 21.375 1.00 52.48 ? 11 ARG K NH2 1 ATOM 6569 N N . SER C 2 12 ? -64.984 -20.529 26.034 1.00 40.28 ? 12 SER K N 1 ATOM 6570 C CA . SER C 2 12 ? -64.897 -20.404 27.473 1.00 39.96 ? 12 SER K CA 1 ATOM 6571 C C . SER C 2 12 ? -65.593 -19.131 27.938 1.00 42.03 ? 12 SER K C 1 ATOM 6572 O O . SER C 2 12 ? -65.866 -18.232 27.140 1.00 37.68 ? 12 SER K O 1 ATOM 6573 C CB . SER C 2 12 ? -63.430 -20.374 27.878 1.00 41.79 ? 12 SER K CB 1 ATOM 6574 O OG . SER C 2 12 ? -62.708 -19.479 27.048 1.00 37.36 ? 12 SER K OG 1 ATOM 6575 N N . ILE C 2 13 ? -65.871 -19.054 29.234 1.00 43.23 ? 13 ILE K N 1 ATOM 6576 C CA . ILE C 2 13 ? -66.591 -17.915 29.785 1.00 44.68 ? 13 ILE K CA 1 ATOM 6577 C C . ILE C 2 13 ? -65.745 -17.152 30.794 1.00 40.95 ? 13 ILE K C 1 ATOM 6578 O O . ILE C 2 13 ? -65.507 -17.634 31.901 1.00 34.03 ? 13 ILE K O 1 ATOM 6579 C CB . ILE C 2 13 ? -67.893 -18.359 30.477 1.00 42.69 ? 13 ILE K CB 1 ATOM 6580 C CG1 . ILE C 2 13 ? -68.621 -19.408 29.632 1.00 40.53 ? 13 ILE K CG1 1 ATOM 6581 C CG2 . ILE C 2 13 ? -68.783 -17.156 30.749 1.00 39.15 ? 13 ILE K CG2 1 ATOM 6582 C CD1 . ILE C 2 13 ? -69.725 -20.137 30.371 1.00 38.33 ? 13 ILE K CD1 1 ATOM 6583 N N . ARG C 2 14 ? -65.298 -15.959 30.411 1.00 45.13 ? 14 ARG K N 1 ATOM 6584 C CA . ARG C 2 14 ? -64.555 -15.094 31.324 1.00 49.58 ? 14 ARG K CA 1 ATOM 6585 C C . ARG C 2 14 ? -65.493 -14.329 32.258 1.00 50.44 ? 14 ARG K C 1 ATOM 6586 O O . ARG C 2 14 ? -66.258 -13.463 31.825 1.00 47.23 ? 14 ARG K O 1 ATOM 6587 C CB . ARG C 2 14 ? -63.654 -14.121 30.557 1.00 55.75 ? 14 ARG K CB 1 ATOM 6588 C CG . ARG C 2 14 ? -62.597 -14.802 29.699 1.00 57.16 ? 14 ARG K CG 1 ATOM 6589 C CD . ARG C 2 14 ? -61.568 -13.810 29.174 1.00 49.40 ? 14 ARG K CD 1 ATOM 6590 N NE . ARG C 2 14 ? -60.703 -13.316 30.238 1.00 48.73 ? 14 ARG K NE 1 ATOM 6591 C CZ . ARG C 2 14 ? -59.677 -13.997 30.737 1.00 54.03 ? 14 ARG K CZ 1 ATOM 6592 N NH1 . ARG C 2 14 ? -59.391 -15.205 30.273 1.00 48.97 1 14 ARG K NH1 1 ATOM 6593 N NH2 . ARG C 2 14 ? -58.937 -13.474 31.704 1.00 60.63 ? 14 ARG K NH2 1 ATOM 6594 N N . LYS C 2 15 ? -65.423 -14.659 33.544 1.00 47.84 ? 15 LYS K N 1 ATOM 6595 C CA . LYS C 2 15 ? -66.267 -14.041 34.555 1.00 40.87 ? 15 LYS K CA 1 ATOM 6596 C C . LYS C 2 15 ? -65.406 -13.494 35.682 1.00 37.75 ? 15 LYS K C 1 ATOM 6597 O O . LYS C 2 15 ? -64.184 -13.590 35.632 1.00 43.81 ? 15 LYS K O 1 ATOM 6598 C CB . LYS C 2 15 ? -67.241 -15.072 35.111 1.00 37.58 ? 15 LYS K CB 1 ATOM 6599 C CG . LYS C 2 15 ? -66.556 -16.235 35.792 1.00 38.66 ? 15 LYS K CG 1 ATOM 6600 C CD . LYS C 2 15 ? -67.411 -17.488 35.742 1.00 43.69 ? 15 LYS K CD 1 ATOM 6601 C CE . LYS C 2 15 ? -68.714 -17.310 36.498 1.00 44.97 ? 15 LYS K CE 1 ATOM 6602 N NZ . LYS C 2 15 ? -69.503 -18.572 36.502 1.00 50.38 1 15 LYS K NZ 1 ATOM 6603 N N . LEU C 2 16 ? -66.047 -12.924 36.698 1.00 37.30 ? 16 LEU K N 1 ATOM 6604 C CA . LEU C 2 16 ? -65.333 -12.392 37.855 1.00 39.14 ? 16 LEU K CA 1 ATOM 6605 C C . LEU C 2 16 ? -65.512 -13.276 39.085 1.00 41.17 ? 16 LEU K C 1 ATOM 6606 O O . LEU C 2 16 ? -66.460 -13.111 39.851 1.00 37.54 ? 16 LEU K O 1 ATOM 6607 C CB . LEU C 2 16 ? -65.782 -10.963 38.166 1.00 37.72 ? 16 LEU K CB 1 ATOM 6608 C CG . LEU C 2 16 ? -64.982 -9.840 37.505 1.00 37.46 ? 16 LEU K CG 1 ATOM 6609 C CD1 . LEU C 2 16 ? -65.105 -9.912 35.993 1.00 38.46 ? 16 LEU K CD1 1 ATOM 6610 C CD2 . LEU C 2 16 ? -65.417 -8.476 38.027 1.00 30.36 ? 16 LEU K CD2 1 ATOM 6611 N N . LYS C 2 39 ? -64.121 -8.422 49.597 1.00 79.52 ? 39 LYS K N 1 ATOM 6612 C CA . LYS C 2 39 ? -62.855 -7.704 49.698 1.00 79.39 ? 39 LYS K CA 1 ATOM 6613 C C . LYS C 2 39 ? -62.235 -7.486 48.316 1.00 74.72 ? 39 LYS K C 1 ATOM 6614 O O . LYS C 2 39 ? -61.756 -6.395 48.005 1.00 63.09 ? 39 LYS K O 1 ATOM 6615 C CB . LYS C 2 39 ? -61.883 -8.443 50.634 1.00 75.66 ? 39 LYS K CB 1 ATOM 6616 C CG . LYS C 2 39 ? -61.615 -9.914 50.278 1.00 74.19 ? 39 LYS K CG 1 ATOM 6617 C CD . LYS C 2 39 ? -60.206 -10.118 49.700 1.00 76.13 ? 39 LYS K CD 1 ATOM 6618 C CE . LYS C 2 39 ? -59.107 -9.841 50.732 1.00 69.81 ? 39 LYS K CE 1 ATOM 6619 N NZ . LYS C 2 39 ? -57.932 -9.140 50.123 1.00 55.31 ? 39 LYS K NZ 1 ATOM 6620 N N . GLN C 2 40 ? -62.268 -8.528 47.490 1.00 82.57 ? 40 GLN K N 1 ATOM 6621 C CA . GLN C 2 40 ? -61.690 -8.495 46.148 1.00 81.29 ? 40 GLN K CA 1 ATOM 6622 C C . GLN C 2 40 ? -62.125 -9.729 45.362 1.00 79.51 ? 40 GLN K C 1 ATOM 6623 O O . GLN C 2 40 ? -62.041 -10.851 45.867 1.00 74.43 ? 40 GLN K O 1 ATOM 6624 C CB . GLN C 2 40 ? -60.160 -8.454 46.219 1.00 73.06 ? 40 GLN K CB 1 ATOM 6625 C CG . GLN C 2 40 ? -59.474 -8.578 44.867 1.00 70.37 ? 40 GLN K CG 1 ATOM 6626 C CD . GLN C 2 40 ? -58.005 -8.940 44.982 1.00 75.24 ? 40 GLN K CD 1 ATOM 6627 O OE1 . GLN C 2 40 ? -57.408 -8.834 46.054 1.00 85.99 ? 40 GLN K OE1 1 ATOM 6628 N NE2 . GLN C 2 40 ? -57.417 -9.378 43.875 1.00 64.78 ? 40 GLN K NE2 1 ATOM 6629 N N . ALA C 2 41 ? -62.583 -9.522 44.130 1.00 73.12 ? 41 ALA K N 1 ATOM 6630 C CA . ALA C 2 41 ? -63.018 -10.623 43.273 1.00 69.56 ? 41 ALA K CA 1 ATOM 6631 C C . ALA C 2 41 ? -61.886 -11.094 42.366 1.00 63.15 ? 41 ALA K C 1 ATOM 6632 O O . ALA C 2 41 ? -60.840 -10.451 42.285 1.00 60.50 ? 41 ALA K O 1 ATOM 6633 C CB . ALA C 2 41 ? -64.221 -10.205 42.445 1.00 72.93 ? 41 ALA K CB 1 ATOM 6634 N N . ILE C 2 42 ? -62.098 -12.211 41.675 1.00 61.33 ? 42 ILE K N 1 ATOM 6635 C CA . ILE C 2 42 ? -61.060 -12.763 40.806 1.00 60.78 ? 42 ILE K CA 1 ATOM 6636 C C . ILE C 2 42 ? -61.575 -13.200 39.423 1.00 55.16 ? 42 ILE K C 1 ATOM 6637 O O . ILE C 2 42 ? -62.486 -14.021 39.309 1.00 47.14 ? 42 ILE K O 1 ATOM 6638 C CB . ILE C 2 42 ? -60.292 -13.916 41.504 1.00 49.06 ? 42 ILE K CB 1 ATOM 6639 C CG1 . ILE C 2 42 ? -59.190 -14.465 40.594 1.00 52.67 ? 42 ILE K CG1 1 ATOM 6640 C CG2 . ILE C 2 42 ? -61.246 -15.013 41.961 1.00 43.37 ? 42 ILE K CG2 1 ATOM 6641 C CD1 . ILE C 2 42 ? -58.021 -13.523 40.403 1.00 51.66 ? 42 ILE K CD1 1 ATOM 6642 N N . GLN C 2 43 ? -60.983 -12.630 38.378 1.00 50.34 ? 43 GLN K N 1 ATOM 6643 C CA . GLN C 2 43 ? -61.338 -12.962 37.005 1.00 41.98 ? 43 GLN K CA 1 ATOM 6644 C C . GLN C 2 43 ? -60.818 -14.341 36.606 1.00 44.06 ? 43 GLN K C 1 ATOM 6645 O O . GLN C 2 43 ? -59.611 -14.568 36.539 1.00 48.39 ? 43 GLN K O 1 ATOM 6646 C CB . GLN C 2 43 ? -60.789 -11.904 36.047 1.00 45.38 ? 43 GLN K CB 1 ATOM 6647 C CG . GLN C 2 43 ? -60.853 -12.297 34.580 1.00 52.53 ? 43 GLN K CG 1 ATOM 6648 C CD . GLN C 2 43 ? -60.154 -11.298 33.673 1.00 65.00 ? 43 GLN K CD 1 ATOM 6649 O OE1 . GLN C 2 43 ? -60.423 -11.239 32.471 1.00 73.02 ? 43 GLN K OE1 1 ATOM 6650 N NE2 . GLN C 2 43 ? -59.248 -10.509 34.245 1.00 54.75 ? 43 GLN K NE2 1 ATOM 6651 N N . ILE C 2 44 ? -61.734 -15.262 36.335 1.00 42.47 ? 44 ILE K N 1 ATOM 6652 C CA . ILE C 2 44 ? -61.345 -16.599 35.911 1.00 46.58 ? 44 ILE K CA 1 ATOM 6653 C C . ILE C 2 44 ? -61.829 -16.896 34.493 1.00 46.28 ? 44 ILE K C 1 ATOM 6654 O O . ILE C 2 44 ? -62.669 -16.178 33.952 1.00 46.58 ? 44 ILE K O 1 ATOM 6655 C CB . ILE C 2 44 ? -61.912 -17.666 36.854 1.00 37.71 ? 44 ILE K CB 1 ATOM 6656 C CG1 . ILE C 2 44 ? -63.421 -17.778 36.670 1.00 31.68 ? 44 ILE K CG1 1 ATOM 6657 C CG2 . ILE C 2 44 ? -61.588 -17.328 38.293 1.00 40.04 ? 44 ILE K CG2 1 ATOM 6658 C CD1 . ILE C 2 44 ? -64.041 -18.852 37.511 1.00 38.83 ? 44 ILE K CD1 1 ATOM 6659 N N . GLU C 2 45 ? -61.274 -17.943 33.888 1.00 42.13 ? 45 GLU K N 1 ATOM 6660 C CA . GLU C 2 45 ? -61.803 -18.478 32.639 1.00 36.90 ? 45 GLU K CA 1 ATOM 6661 C C . GLU C 2 45 ? -62.106 -19.961 32.813 1.00 32.83 ? 45 GLU K C 1 ATOM 6662 O O . GLU C 2 45 ? -61.301 -20.716 33.356 1.00 36.53 ? 45 GLU K O 1 ATOM 6663 C CB . GLU C 2 45 ? -60.845 -18.255 31.462 1.00 38.81 ? 45 GLU K CB 1 ATOM 6664 C CG . GLU C 2 45 ? -61.230 -19.061 30.217 1.00 36.67 ? 45 GLU K CG 1 ATOM 6665 C CD . GLU C 2 45 ? -60.495 -18.637 28.953 1.00 36.85 ? 45 GLU K CD 1 ATOM 6666 O OE1 . GLU C 2 45 ? -59.628 -19.402 28.476 1.00 30.35 ? 45 GLU K OE1 1 ATOM 6667 O OE2 . GLU C 2 45 ? -60.805 -17.549 28.421 1.00 38.90 1 45 GLU K OE2 1 ATOM 6668 N N . GLU C 2 46 ? -63.278 -20.373 32.355 1.00 37.01 ? 46 GLU K N 1 ATOM 6669 C CA . GLU C 2 46 ? -63.727 -21.736 32.558 1.00 35.86 ? 46 GLU K CA 1 ATOM 6670 C C . GLU C 2 46 ? -64.270 -22.334 31.263 1.00 38.26 ? 46 GLU K C 1 ATOM 6671 O O . GLU C 2 46 ? -65.024 -21.685 30.531 1.00 31.01 ? 46 GLU K O 1 ATOM 6672 C CB . GLU C 2 46 ? -64.796 -21.761 33.646 1.00 32.01 ? 46 GLU K CB 1 ATOM 6673 C CG . GLU C 2 46 ? -65.044 -23.117 34.256 1.00 35.22 ? 46 GLU K CG 1 ATOM 6674 C CD . GLU C 2 46 ? -65.977 -23.036 35.445 1.00 49.39 ? 46 GLU K CD 1 ATOM 6675 O OE1 . GLU C 2 46 ? -67.089 -22.485 35.288 1.00 50.72 ? 46 GLU K OE1 1 ATOM 6676 O OE2 . GLU C 2 46 ? -65.592 -23.506 36.540 1.00 53.47 1 46 GLU K OE2 1 ATOM 6677 N N . CYS C 2 47 ? -63.856 -23.567 30.987 1.00 35.63 ? 47 CYS K N 1 ATOM 6678 C CA . CYS C 2 47 ? -64.341 -24.327 29.846 1.00 29.36 ? 47 CYS K CA 1 ATOM 6679 C C . CYS C 2 47 ? -65.857 -24.270 29.767 1.00 42.30 ? 47 CYS K C 1 ATOM 6680 O O . CYS C 2 47 ? -66.542 -24.552 30.752 1.00 43.54 ? 47 CYS K O 1 ATOM 6681 C CB . CYS C 2 47 ? -63.913 -25.784 29.981 1.00 25.83 ? 47 CYS K CB 1 ATOM 6682 S SG . CYS C 2 47 ? -62.610 -26.280 28.870 1.00 16.00 ? 47 CYS K SG 1 ATOM 6683 N N . GLU C 2 48 ? -66.379 -23.893 28.602 1.00 43.93 ? 48 GLU K N 1 ATOM 6684 C CA . GLU C 2 48 ? -67.820 -23.889 28.391 1.00 40.44 ? 48 GLU K CA 1 ATOM 6685 C C . GLU C 2 48 ? -68.353 -25.296 28.594 1.00 39.36 ? 48 GLU K C 1 ATOM 6686 O O . GLU C 2 48 ? -69.321 -25.506 29.323 1.00 47.56 ? 48 GLU K O 1 ATOM 6687 C CB . GLU C 2 48 ? -68.165 -23.402 26.987 1.00 43.48 ? 48 GLU K CB 1 ATOM 6688 C CG . GLU C 2 48 ? -69.662 -23.394 26.681 1.00 50.14 ? 48 GLU K CG 1 ATOM 6689 C CD . GLU C 2 48 ? -70.403 -22.268 27.384 1.00 59.93 ? 48 GLU K CD 1 ATOM 6690 O OE1 . GLU C 2 48 ? -70.638 -21.219 26.743 1.00 55.92 ? 48 GLU K OE1 1 ATOM 6691 O OE2 . GLU C 2 48 ? -70.752 -22.431 28.574 1.00 59.15 1 48 GLU K OE2 1 ATOM 6692 N N . GLY C 2 49 ? -67.705 -26.259 27.953 1.00 33.56 ? 49 GLY K N 1 ATOM 6693 C CA . GLY C 2 49 ? -68.077 -27.650 28.106 1.00 40.43 ? 49 GLY K CA 1 ATOM 6694 C C . GLY C 2 49 ? -66.935 -28.476 28.658 1.00 56.19 ? 49 GLY K C 1 ATOM 6695 O O . GLY C 2 49 ? -65.768 -28.092 28.557 1.00 55.14 ? 49 GLY K O 1 ATOM 6696 N N . ALA C 2 50 ? -67.267 -29.614 29.254 1.00 62.03 ? 50 ALA K N 1 ATOM 6697 C CA . ALA C 2 50 ? -66.245 -30.523 29.750 1.00 60.61 ? 50 ALA K CA 1 ATOM 6698 C C . ALA C 2 50 ? -65.961 -31.609 28.716 1.00 50.42 ? 50 ALA K C 1 ATOM 6699 O O . ALA C 2 50 ? -66.844 -32.397 28.377 1.00 49.27 ? 50 ALA K O 1 ATOM 6700 C CB . ALA C 2 50 ? -66.670 -31.135 31.078 1.00 60.73 ? 50 ALA K CB 1 ATOM 6701 N N . ASP C 2 51 ? -64.731 -31.615 28.206 1.00 45.52 ? 51 ASP K N 1 ATOM 6702 C CA . ASP C 2 51 ? -64.251 -32.626 27.261 1.00 48.46 ? 51 ASP K CA 1 ATOM 6703 C C . ASP C 2 51 ? -64.892 -32.543 25.879 1.00 48.09 ? 51 ASP K C 1 ATOM 6704 O O . ASP C 2 51 ? -64.991 -33.543 25.164 1.00 44.23 ? 51 ASP K O 1 ATOM 6705 C CB . ASP C 2 51 ? -64.402 -34.037 27.837 1.00 48.59 ? 51 ASP K CB 1 ATOM 6706 C CG . ASP C 2 51 ? -63.810 -34.158 29.219 1.00 67.55 ? 51 ASP K CG 1 ATOM 6707 O OD1 . ASP C 2 51 ? -62.743 -33.550 29.462 1.00 72.50 ? 51 ASP K OD1 1 ATOM 6708 O OD2 . ASP C 2 51 ? -64.419 -34.850 30.065 1.00 71.48 1 51 ASP K OD2 1 ATOM 6709 N N . GLN C 2 52 ? -65.317 -31.346 25.496 1.00 43.72 ? 52 GLN K N 1 ATOM 6710 C CA . GLN C 2 52 ? -65.838 -31.147 24.155 1.00 44.90 ? 52 GLN K CA 1 ATOM 6711 C C . GLN C 2 52 ? -64.680 -31.131 23.162 1.00 39.71 ? 52 GLN K C 1 ATOM 6712 O O . GLN C 2 52 ? -63.625 -30.574 23.455 1.00 40.20 ? 52 GLN K O 1 ATOM 6713 C CB . GLN C 2 52 ? -66.634 -29.840 24.075 1.00 51.90 ? 52 GLN K CB 1 ATOM 6714 C CG . GLN C 2 52 ? -67.911 -29.815 24.918 1.00 51.22 ? 52 GLN K CG 1 ATOM 6715 C CD . GLN C 2 52 ? -69.036 -30.670 24.339 1.00 51.29 ? 52 GLN K CD 1 ATOM 6716 O OE1 . GLN C 2 52 ? -68.918 -31.221 23.243 1.00 49.68 ? 52 GLN K OE1 1 ATOM 6717 N NE2 . GLN C 2 52 ? -70.136 -30.779 25.080 1.00 51.85 ? 52 GLN K NE2 1 ATOM 6718 N N . PRO C 2 53 ? -64.868 -31.764 21.993 1.00 34.80 ? 53 PRO K N 1 ATOM 6719 C CA . PRO C 2 53 ? -63.894 -31.735 20.898 1.00 29.38 ? 53 PRO K CA 1 ATOM 6720 C C . PRO C 2 53 ? -63.480 -30.314 20.554 1.00 29.71 ? 53 PRO K C 1 ATOM 6721 O O . PRO C 2 53 ? -64.269 -29.385 20.714 1.00 27.75 ? 53 PRO K O 1 ATOM 6722 C CB . PRO C 2 53 ? -64.670 -32.341 19.735 1.00 28.79 ? 53 PRO K CB 1 ATOM 6723 C CG . PRO C 2 53 ? -65.595 -33.292 20.383 1.00 45.03 ? 53 PRO K CG 1 ATOM 6724 C CD . PRO C 2 53 ? -66.002 -32.651 21.686 1.00 48.62 ? 53 PRO K CD 1 ATOM 6725 N N . CYS C 2 54 ? -62.245 -30.154 20.093 1.00 30.43 ? 54 CYS K N 1 ATOM 6726 C CA . CYS C 2 54 ? -61.699 -28.839 19.808 1.00 22.02 ? 54 CYS K CA 1 ATOM 6727 C C . CYS C 2 54 ? -62.189 -28.379 18.457 1.00 16.83 ? 54 CYS K C 1 ATOM 6728 O O . CYS C 2 54 ? -62.559 -29.193 17.622 1.00 19.20 ? 54 CYS K O 1 ATOM 6729 C CB . CYS C 2 54 ? -60.175 -28.897 19.801 1.00 21.15 ? 54 CYS K CB 1 ATOM 6730 S SG . CYS C 2 54 ? -59.468 -29.743 21.219 1.00 27.74 ? 54 CYS K SG 1 ATOM 6731 N N . ASP C 2 55 ? -62.186 -27.071 18.241 1.00 17.28 ? 55 ASP K N 1 ATOM 6732 C CA . ASP C 2 55 ? -62.571 -26.518 16.950 1.00 19.48 ? 55 ASP K CA 1 ATOM 6733 C C . ASP C 2 55 ? -61.388 -26.568 15.995 1.00 16.48 ? 55 ASP K C 1 ATOM 6734 O O . ASP C 2 55 ? -60.249 -26.722 16.427 1.00 18.29 ? 55 ASP K O 1 ATOM 6735 C CB . ASP C 2 55 ? -63.048 -25.075 17.111 1.00 23.92 ? 55 ASP K CB 1 ATOM 6736 C CG . ASP C 2 55 ? -64.406 -24.829 16.470 1.00 21.88 ? 55 ASP K CG 1 ATOM 6737 O OD1 . ASP C 2 55 ? -64.494 -24.836 15.219 1.00 17.33 ? 55 ASP K OD1 1 ATOM 6738 O OD2 . ASP C 2 55 ? -65.380 -24.616 17.227 1.00 16.84 1 55 ASP K OD2 1 ATOM 6739 N N . PHE C 2 56 ? -61.665 -26.457 14.699 1.00 16.33 ? 56 PHE K N 1 ATOM 6740 C CA . PHE C 2 56 ? -60.625 -26.424 13.668 1.00 16.33 ? 56 PHE K CA 1 ATOM 6741 C C . PHE C 2 56 ? -59.638 -27.584 13.811 1.00 15.77 ? 56 PHE K C 1 ATOM 6742 O O . PHE C 2 56 ? -58.488 -27.493 13.391 1.00 17.81 ? 56 PHE K O 1 ATOM 6743 C CB . PHE C 2 56 ? -59.878 -25.087 13.704 1.00 14.88 ? 56 PHE K CB 1 ATOM 6744 C CG . PHE C 2 56 ? -60.782 -23.879 13.803 1.00 15.43 ? 56 PHE K CG 1 ATOM 6745 C CD1 . PHE C 2 56 ? -61.290 -23.277 12.666 1.00 13.99 ? 56 PHE K CD1 1 ATOM 6746 C CD2 . PHE C 2 56 ? -61.106 -23.336 15.034 1.00 15.00 ? 56 PHE K CD2 1 ATOM 6747 C CE1 . PHE C 2 56 ? -62.109 -22.169 12.760 1.00 11.20 ? 56 PHE K CE1 1 ATOM 6748 C CE2 . PHE C 2 56 ? -61.926 -22.229 15.128 1.00 13.92 ? 56 PHE K CE2 1 ATOM 6749 C CZ . PHE C 2 56 ? -62.424 -21.646 13.990 1.00 11.65 ? 56 PHE K CZ 1 ATOM 6750 N N . ALA C 2 57 ? -60.106 -28.672 14.409 1.00 12.91 ? 57 ALA K N 1 ATOM 6751 C CA . ALA C 2 57 ? -59.258 -29.809 14.718 1.00 13.76 ? 57 ALA K CA 1 ATOM 6752 C C . ALA C 2 57 ? -59.470 -30.953 13.726 1.00 17.20 ? 57 ALA K C 1 ATOM 6753 O O . ALA C 2 57 ? -59.467 -32.129 14.103 1.00 16.54 ? 57 ALA K O 1 ATOM 6754 C CB . ALA C 2 57 ? -59.540 -30.272 16.123 1.00 15.86 ? 57 ALA K CB 1 ATOM 6755 N N . ALA C 2 58 ? -59.649 -30.606 12.457 1.00 16.32 ? 58 ALA K N 1 ATOM 6756 C CA . ALA C 2 58 ? -59.942 -31.598 11.435 1.00 14.16 ? 58 ALA K CA 1 ATOM 6757 C C . ALA C 2 58 ? -58.667 -32.153 10.804 1.00 15.05 ? 58 ALA K C 1 ATOM 6758 O O . ALA C 2 58 ? -58.671 -33.247 10.234 1.00 15.12 ? 58 ALA K O 1 ATOM 6759 C CB . ALA C 2 58 ? -60.846 -30.997 10.368 1.00 9.46 ? 58 ALA K CB 1 ATOM 6760 N N . ASN C 2 59 ? -57.577 -31.399 10.910 1.00 14.03 ? 59 ASN K N 1 ATOM 6761 C CA . ASN C 2 59 ? -56.353 -31.740 10.190 1.00 13.25 ? 59 ASN K CA 1 ATOM 6762 C C . ASN C 2 59 ? -55.315 -32.484 11.026 1.00 12.78 ? 59 ASN K C 1 ATOM 6763 O O . ASN C 2 59 ? -54.413 -33.124 10.484 1.00 12.11 ? 59 ASN K O 1 ATOM 6764 C CB . ASN C 2 59 ? -55.739 -30.495 9.555 1.00 10.48 ? 59 ASN K CB 1 ATOM 6765 C CG . ASN C 2 59 ? -55.312 -30.728 8.126 1.00 7.22 ? 59 ASN K CG 1 ATOM 6766 O OD1 . ASN C 2 59 ? -54.825 -31.803 7.778 1.00 6.08 ? 59 ASN K OD1 1 ATOM 6767 N ND2 . ASN C 2 59 ? -55.496 -29.720 7.287 1.00 6.87 ? 59 ASN K ND2 1 ATOM 6768 N N . PHE C 2 60 ? -55.451 -32.394 12.343 1.00 14.27 ? 60 PHE K N 1 ATOM 6769 C CA . PHE C 2 60 ? -54.627 -33.174 13.256 1.00 14.56 ? 60 PHE K CA 1 ATOM 6770 C C . PHE C 2 60 ? -54.859 -34.660 13.029 1.00 15.18 ? 60 PHE K C 1 ATOM 6771 O O . PHE C 2 60 ? -55.972 -35.068 12.699 1.00 16.08 ? 60 PHE K O 1 ATOM 6772 C CB . PHE C 2 60 ? -54.933 -32.796 14.705 1.00 14.17 ? 60 PHE K CB 1 ATOM 6773 C CG . PHE C 2 60 ? -54.609 -31.373 15.027 1.00 13.56 ? 60 PHE K CG 1 ATOM 6774 C CD1 . PHE C 2 60 ? -53.293 -30.944 15.063 1.00 14.19 ? 60 PHE K CD1 1 ATOM 6775 C CD2 . PHE C 2 60 ? -55.614 -30.458 15.272 1.00 15.34 ? 60 PHE K CD2 1 ATOM 6776 C CE1 . PHE C 2 60 ? -52.986 -29.632 15.346 1.00 14.96 ? 60 PHE K CE1 1 ATOM 6777 C CE2 . PHE C 2 60 ? -55.313 -29.141 15.554 1.00 17.96 ? 60 PHE K CE2 1 ATOM 6778 C CZ . PHE C 2 60 ? -53.996 -28.728 15.593 1.00 17.45 ? 60 PHE K CZ 1 ATOM 6779 N N . PRO C 2 61 ? -53.801 -35.469 13.193 1.00 15.58 ? 61 PRO K N 1 ATOM 6780 C CA . PRO C 2 61 ? -53.854 -36.907 12.920 1.00 17.09 ? 61 PRO K CA 1 ATOM 6781 C C . PRO C 2 61 ? -54.967 -37.607 13.678 1.00 21.58 ? 61 PRO K C 1 ATOM 6782 O O . PRO C 2 61 ? -55.412 -37.131 14.725 1.00 20.03 ? 61 PRO K O 1 ATOM 6783 C CB . PRO C 2 61 ? -52.494 -37.397 13.410 1.00 17.88 ? 61 PRO K CB 1 ATOM 6784 C CG . PRO C 2 61 ? -51.609 -36.226 13.228 1.00 16.44 ? 61 PRO K CG 1 ATOM 6785 C CD . PRO C 2 61 ? -52.448 -35.046 13.593 1.00 15.02 ? 61 PRO K CD 1 ATOM 6786 N N . GLN C 2 62 ? -55.407 -38.739 13.138 1.00 24.25 ? 62 GLN K N 1 ATOM 6787 C CA . GLN C 2 62 ? -56.485 -39.519 13.733 1.00 29.05 ? 62 GLN K CA 1 ATOM 6788 C C . GLN C 2 62 ? -56.137 -39.912 15.159 1.00 27.22 ? 62 GLN K C 1 ATOM 6789 O O . GLN C 2 62 ? -57.009 -40.215 15.970 1.00 28.19 ? 62 GLN K O 1 ATOM 6790 C CB . GLN C 2 62 ? -56.741 -40.778 12.902 1.00 33.68 ? 62 GLN K CB 1 ATOM 6791 C CG . GLN C 2 62 ? -57.953 -41.569 13.353 1.00 30.86 ? 62 GLN K CG 1 ATOM 6792 C CD . GLN C 2 62 ? -59.196 -40.706 13.415 1.00 36.34 ? 62 GLN K CD 1 ATOM 6793 O OE1 . GLN C 2 62 ? -59.683 -40.226 12.387 1.00 32.18 ? 62 GLN K OE1 1 ATOM 6794 N NE2 . GLN C 2 62 ? -59.711 -40.489 14.624 1.00 27.95 ? 62 GLN K NE2 1 ATOM 6795 N N . SER C 2 63 ? -54.844 -39.890 15.450 1.00 27.63 ? 63 SER K N 1 ATOM 6796 C CA . SER C 2 63 ? -54.318 -40.354 16.718 1.00 26.19 ? 63 SER K CA 1 ATOM 6797 C C . SER C 2 63 ? -54.411 -39.279 17.791 1.00 26.76 ? 63 SER K C 1 ATOM 6798 O O . SER C 2 63 ? -54.721 -39.581 18.940 1.00 32.03 ? 63 SER K O 1 ATOM 6799 C CB . SER C 2 63 ? -52.861 -40.776 16.531 1.00 34.09 ? 63 SER K CB 1 ATOM 6800 O OG . SER C 2 63 ? -52.590 -41.048 15.160 1.00 33.16 ? 63 SER K OG 1 ATOM 6801 N N . TYR C 2 64 ? -54.157 -38.027 17.408 1.00 27.87 ? 64 TYR K N 1 ATOM 6802 C CA . TYR C 2 64 ? -54.036 -36.926 18.372 1.00 26.39 ? 64 TYR K CA 1 ATOM 6803 C C . TYR C 2 64 ? -55.272 -36.749 19.242 1.00 24.57 ? 64 TYR K C 1 ATOM 6804 O O . TYR C 2 64 ? -55.164 -36.299 20.380 1.00 28.04 ? 64 TYR K O 1 ATOM 6805 C CB . TYR C 2 64 ? -53.711 -35.595 17.681 1.00 22.27 ? 64 TYR K CB 1 ATOM 6806 C CG . TYR C 2 64 ? -52.294 -35.469 17.176 1.00 23.28 ? 64 TYR K CG 1 ATOM 6807 C CD1 . TYR C 2 64 ? -51.527 -36.596 16.902 1.00 29.98 ? 64 TYR K CD1 1 ATOM 6808 C CD2 . TYR C 2 64 ? -51.717 -34.222 16.983 1.00 23.56 ? 64 TYR K CD2 1 ATOM 6809 C CE1 . TYR C 2 64 ? -50.226 -36.488 16.441 1.00 31.48 ? 64 TYR K CE1 1 ATOM 6810 C CE2 . TYR C 2 64 ? -50.413 -34.101 16.521 1.00 31.14 ? 64 TYR K CE2 1 ATOM 6811 C CZ . TYR C 2 64 ? -49.674 -35.240 16.254 1.00 31.83 ? 64 TYR K CZ 1 ATOM 6812 O OH . TYR C 2 64 ? -48.381 -35.138 15.796 1.00 27.78 ? 64 TYR K OH 1 ATOM 6813 N N . ASN C 2 65 ? -56.430 -37.111 18.696 1.00 21.73 ? 65 ASN K N 1 ATOM 6814 C CA . ASN C 2 65 ? -57.710 -36.964 19.379 1.00 22.00 ? 65 ASN K CA 1 ATOM 6815 C C . ASN C 2 65 ? -57.798 -35.702 20.229 1.00 19.75 ? 65 ASN K C 1 ATOM 6816 O O . ASN C 2 65 ? -57.719 -35.773 21.454 1.00 24.39 ? 65 ASN K O 1 ATOM 6817 C CB . ASN C 2 65 ? -58.001 -38.202 20.230 1.00 27.57 ? 65 ASN K CB 1 ATOM 6818 C CG . ASN C 2 65 ? -59.347 -38.122 20.937 1.00 40.07 ? 65 ASN K CG 1 ATOM 6819 O OD1 . ASN C 2 65 ? -59.408 -37.845 22.135 1.00 46.81 ? 65 ASN K OD1 1 ATOM 6820 N ND2 . ASN C 2 65 ? -60.431 -38.358 20.197 1.00 23.26 ? 65 ASN K ND2 1 ATOM 6821 N N . PRO C 2 66 ? -57.911 -34.538 19.578 1.00 14.72 ? 66 PRO K N 1 ATOM 6822 C CA . PRO C 2 66 ? -57.978 -33.266 20.303 1.00 18.03 ? 66 PRO K CA 1 ATOM 6823 C C . PRO C 2 66 ? -59.223 -33.100 21.173 1.00 21.43 ? 66 PRO K C 1 ATOM 6824 O O . PRO C 2 66 ? -60.346 -33.278 20.712 1.00 24.96 ? 66 PRO K O 1 ATOM 6825 C CB . PRO C 2 66 ? -57.926 -32.212 19.193 1.00 15.69 ? 66 PRO K CB 1 ATOM 6826 C CG . PRO C 2 66 ? -58.144 -32.949 17.930 1.00 22.42 ? 66 PRO K CG 1 ATOM 6827 C CD . PRO C 2 66 ? -57.696 -34.341 18.138 1.00 18.29 ? 66 PRO K CD 1 ATOM 6828 N N . ILE C 2 67 ? -58.986 -32.755 22.437 1.00 24.15 ? 67 ILE K N 1 ATOM 6829 C CA . ILE C 2 67 ? -60.013 -32.599 23.458 1.00 22.35 ? 67 ILE K CA 1 ATOM 6830 C C . ILE C 2 67 ? -59.747 -31.285 24.181 1.00 30.50 ? 67 ILE K C 1 ATOM 6831 O O . ILE C 2 67 ? -58.592 -30.888 24.348 1.00 32.91 ? 67 ILE K O 1 ATOM 6832 C CB . ILE C 2 67 ? -59.916 -33.731 24.503 1.00 23.93 ? 67 ILE K CB 1 ATOM 6833 C CG1 . ILE C 2 67 ? -59.950 -35.100 23.827 1.00 25.91 ? 67 ILE K CG1 1 ATOM 6834 C CG2 . ILE C 2 67 ? -61.023 -33.622 25.537 1.00 30.30 ? 67 ILE K CG2 1 ATOM 6835 C CD1 . ILE C 2 67 ? -61.226 -35.366 23.060 1.00 31.91 ? 67 ILE K CD1 1 ATOM 6836 N N . CYS C 2 68 ? -60.802 -30.603 24.611 1.00 31.27 ? 68 CYS K N 1 ATOM 6837 C CA . CYS C 2 68 ? -60.631 -29.378 25.386 1.00 31.64 ? 68 CYS K CA 1 ATOM 6838 C C . CYS C 2 68 ? -60.388 -29.697 26.857 1.00 29.07 ? 68 CYS K C 1 ATOM 6839 O O . CYS C 2 68 ? -61.075 -30.537 27.438 1.00 35.50 ? 68 CYS K O 1 ATOM 6840 C CB . CYS C 2 68 ? -61.849 -28.465 25.227 1.00 30.17 ? 68 CYS K CB 1 ATOM 6841 S SG . CYS C 2 68 ? -62.084 -27.858 23.540 1.00 31.02 ? 68 CYS K SG 1 ATOM 6842 N N . LYS C 2 69 ? -59.409 -29.028 27.457 1.00 25.47 ? 69 LYS K N 1 ATOM 6843 C CA . LYS C 2 69 ? -59.090 -29.256 28.864 1.00 29.52 ? 69 LYS K CA 1 ATOM 6844 C C . LYS C 2 69 ? -59.204 -27.987 29.705 1.00 27.09 ? 69 LYS K C 1 ATOM 6845 O O . LYS C 2 69 ? -59.070 -26.874 29.195 1.00 24.72 ? 69 LYS K O 1 ATOM 6846 C CB . LYS C 2 69 ? -57.684 -29.842 29.017 1.00 30.04 ? 69 LYS K CB 1 ATOM 6847 C CG . LYS C 2 69 ? -57.493 -31.213 28.400 1.00 30.74 ? 69 LYS K CG 1 ATOM 6848 C CD . LYS C 2 69 ? -58.310 -32.269 29.115 1.00 34.51 ? 69 LYS K CD 1 ATOM 6849 C CE . LYS C 2 69 ? -58.023 -33.649 28.546 1.00 47.58 ? 69 LYS K CE 1 ATOM 6850 N NZ . LYS C 2 69 ? -59.022 -34.653 29.006 1.00 68.21 1 69 LYS K NZ 1 ATOM 6851 N N . GLN C 2 70 ? -59.436 -28.176 31.001 1.00 25.92 ? 70 GLN K N 1 ATOM 6852 C CA . GLN C 2 70 ? -59.548 -27.074 31.946 1.00 25.46 ? 70 GLN K CA 1 ATOM 6853 C C . GLN C 2 70 ? -58.239 -26.871 32.708 1.00 32.24 ? 70 GLN K C 1 ATOM 6854 O O . GLN C 2 70 ? -57.808 -27.752 33.452 1.00 31.38 ? 70 GLN K O 1 ATOM 6855 C CB . GLN C 2 70 ? -60.687 -27.352 32.927 1.00 21.92 ? 70 GLN K CB 1 ATOM 6856 C CG . GLN C 2 70 ? -60.770 -26.375 34.080 1.00 28.18 ? 70 GLN K CG 1 ATOM 6857 C CD . GLN C 2 70 ? -61.138 -24.979 33.634 1.00 29.61 ? 70 GLN K CD 1 ATOM 6858 O OE1 . GLN C 2 70 ? -62.305 -24.689 33.373 1.00 31.77 ? 70 GLN K OE1 1 ATOM 6859 N NE2 . GLN C 2 70 ? -60.143 -24.103 33.545 1.00 27.93 ? 70 GLN K NE2 1 ATOM 6860 N N . HIS C 2 71 ? -57.607 -25.713 32.521 1.00 34.75 ? 71 HIS K N 1 ATOM 6861 C CA . HIS C 2 71 ? -56.355 -25.394 33.217 1.00 38.48 ? 71 HIS K CA 1 ATOM 6862 C C . HIS C 2 71 ? -56.561 -24.428 34.381 1.00 44.20 ? 71 HIS K C 1 ATOM 6863 O O . HIS C 2 71 ? -57.383 -23.510 34.297 1.00 46.79 ? 71 HIS K O 1 ATOM 6864 C CB . HIS C 2 71 ? -55.323 -24.810 32.251 1.00 38.36 ? 71 HIS K CB 1 ATOM 6865 C CG . HIS C 2 71 ? -54.738 -25.817 31.314 1.00 49.76 ? 71 HIS K CG 1 ATOM 6866 N ND1 . HIS C 2 71 ? -53.524 -25.633 30.686 1.00 57.34 ? 71 HIS K ND1 1 ATOM 6867 C CD2 . HIS C 2 71 ? -55.198 -27.022 30.900 1.00 42.40 ? 71 HIS K CD2 1 ATOM 6868 C CE1 . HIS C 2 71 ? -53.263 -26.682 29.925 1.00 52.20 ? 71 HIS K CE1 1 ATOM 6869 N NE2 . HIS C 2 71 ? -54.263 -27.538 30.036 1.00 46.13 ? 71 HIS K NE2 1 ATOM 6870 N N . TYR C 2 72 ? -55.798 -24.626 35.455 1.00 33.87 ? 72 TYR K N 1 ATOM 6871 C CA . TYR C 2 72 ? -55.954 -23.818 36.659 1.00 30.66 ? 72 TYR K CA 1 ATOM 6872 C C . TYR C 2 72 ? -54.744 -22.939 36.969 1.00 35.87 ? 72 TYR K C 1 ATOM 6873 O O . TYR C 2 72 ? -53.812 -22.841 36.175 1.00 37.64 ? 72 TYR K O 1 ATOM 6874 C CB . TYR C 2 72 ? -56.264 -24.711 37.855 1.00 31.43 ? 72 TYR K CB 1 ATOM 6875 C CG . TYR C 2 72 ? -57.486 -25.573 37.666 1.00 33.47 ? 72 TYR K CG 1 ATOM 6876 C CD1 . TYR C 2 72 ? -58.749 -25.104 37.999 1.00 34.54 ? 72 TYR K CD1 1 ATOM 6877 C CD2 . TYR C 2 72 ? -57.377 -26.860 37.158 1.00 37.16 ? 72 TYR K CD2 1 ATOM 6878 C CE1 . TYR C 2 72 ? -59.873 -25.893 37.826 1.00 39.02 ? 72 TYR K CE1 1 ATOM 6879 C CE2 . TYR C 2 72 ? -58.494 -27.659 36.984 1.00 35.61 ? 72 TYR K CE2 1 ATOM 6880 C CZ . TYR C 2 72 ? -59.738 -27.171 37.318 1.00 36.84 ? 72 TYR K CZ 1 ATOM 6881 O OH . TYR C 2 72 ? -60.848 -27.964 37.141 1.00 32.47 ? 72 TYR K OH 1 ATOM 6882 N N . THR C 2 73 ? -54.783 -22.293 38.132 1.00 43.41 ? 73 THR K N 1 ATOM 6883 C CA . THR C 2 73 ? -53.688 -21.449 38.612 1.00 40.04 ? 73 THR K CA 1 ATOM 6884 C C . THR C 2 73 ? -53.697 -21.410 40.141 1.00 44.48 ? 73 THR K C 1 ATOM 6885 O O . THR C 2 73 ? -54.446 -22.148 40.789 1.00 41.78 ? 73 THR K O 1 ATOM 6886 C CB . THR C 2 73 ? -53.768 -20.005 38.046 1.00 31.39 ? 73 THR K CB 1 ATOM 6887 O OG1 . THR C 2 73 ? -52.795 -19.832 37.009 1.00 25.58 ? 73 THR K OG1 1 ATOM 6888 C CG2 . THR C 2 73 ? -53.504 -18.982 39.133 1.00 32.72 ? 73 THR K CG2 1 ATOM 6889 N N . LYS C 2 94 ? -56.424 -23.718 44.481 1.00 38.27 ? 94 LYS K N 1 ATOM 6890 C CA . LYS C 2 94 ? -56.669 -24.073 43.085 1.00 47.65 ? 94 LYS K CA 1 ATOM 6891 C C . LYS C 2 94 ? -57.769 -23.197 42.490 1.00 54.87 ? 94 LYS K C 1 ATOM 6892 O O . LYS C 2 94 ? -58.771 -22.915 43.151 1.00 54.82 ? 94 LYS K O 1 ATOM 6893 C CB . LYS C 2 94 ? -57.052 -25.550 42.965 1.00 47.20 ? 94 LYS K CB 1 ATOM 6894 C CG . LYS C 2 94 ? -56.976 -26.092 41.546 1.00 42.58 ? 94 LYS K CG 1 ATOM 6895 C CD . LYS C 2 94 ? -57.450 -27.539 41.460 1.00 44.32 ? 94 LYS K CD 1 ATOM 6896 C CE . LYS C 2 94 ? -58.963 -27.645 41.622 1.00 51.76 ? 94 LYS K CE 1 ATOM 6897 N NZ . LYS C 2 94 ? -59.476 -29.025 41.354 1.00 47.11 1 94 LYS K NZ 1 ATOM 6898 N N . ILE C 2 95 ? -57.582 -22.776 41.240 1.00 50.33 ? 95 ILE K N 1 ATOM 6899 C CA . ILE C 2 95 ? -58.506 -21.837 40.598 1.00 45.57 ? 95 ILE K CA 1 ATOM 6900 C C . ILE C 2 95 ? -58.326 -21.787 39.075 1.00 45.89 ? 95 ILE K C 1 ATOM 6901 O O . ILE C 2 95 ? -57.204 -21.641 38.590 1.00 43.71 ? 95 ILE K O 1 ATOM 6902 C CB . ILE C 2 95 ? -58.342 -20.413 41.190 1.00 44.19 ? 95 ILE K CB 1 ATOM 6903 C CG1 . ILE C 2 95 ? -59.126 -19.388 40.376 1.00 37.86 ? 95 ILE K CG1 1 ATOM 6904 C CG2 . ILE C 2 95 ? -56.866 -20.013 41.260 1.00 43.00 ? 95 ILE K CG2 1 ATOM 6905 C CD1 . ILE C 2 95 ? -58.931 -17.977 40.855 1.00 34.16 ? 95 ILE K CD1 1 ATOM 6906 N N . PRO C 2 96 ? -59.436 -21.914 38.320 1.00 45.58 ? 96 PRO K N 1 ATOM 6907 C CA . PRO C 2 96 ? -59.444 -21.855 36.851 1.00 37.07 ? 96 PRO K CA 1 ATOM 6908 C C . PRO C 2 96 ? -58.695 -20.643 36.303 1.00 40.90 ? 96 PRO K C 1 ATOM 6909 O O . PRO C 2 96 ? -58.744 -19.568 36.901 1.00 45.97 ? 96 PRO K O 1 ATOM 6910 C CB . PRO C 2 96 ? -60.930 -21.739 36.523 1.00 32.68 ? 96 PRO K CB 1 ATOM 6911 C CG . PRO C 2 96 ? -61.601 -22.460 37.628 1.00 34.82 ? 96 PRO K CG 1 ATOM 6912 C CD . PRO C 2 96 ? -60.785 -22.169 38.859 1.00 43.73 ? 96 PRO K CD 1 ATOM 6913 N N . SER C 2 97 ? -58.007 -20.819 35.179 1.00 39.80 ? 97 SER K N 1 ATOM 6914 C CA . SER C 2 97 ? -57.189 -19.748 34.614 1.00 42.56 ? 97 SER K CA 1 ATOM 6915 C C . SER C 2 97 ? -57.498 -19.542 33.141 1.00 31.46 ? 97 SER K C 1 ATOM 6916 O O . SER C 2 97 ? -57.547 -18.409 32.655 1.00 26.65 ? 97 SER K O 1 ATOM 6917 C CB . SER C 2 97 ? -55.694 -20.043 34.808 1.00 44.21 ? 97 SER K CB 1 ATOM 6918 O OG . SER C 2 97 ? -55.278 -21.194 34.085 1.00 42.09 ? 97 SER K OG 1 ATOM 6919 N N . CYS C 2 98 ? -57.698 -20.653 32.443 1.00 29.72 ? 98 CYS K N 1 ATOM 6920 C CA . CYS C 2 98 ? -58.047 -20.633 31.030 1.00 37.95 ? 98 CYS K CA 1 ATOM 6921 C C . CYS C 2 98 ? -58.397 -22.037 30.559 1.00 34.14 ? 98 CYS K C 1 ATOM 6922 O O . CYS C 2 98 ? -58.337 -22.997 31.333 1.00 30.93 ? 98 CYS K O 1 ATOM 6923 C CB . CYS C 2 98 ? -56.903 -20.076 30.182 1.00 38.33 ? 98 CYS K CB 1 ATOM 6924 S SG . CYS C 2 98 ? -55.665 -21.305 29.755 1.00 45.66 ? 98 CYS K SG 1 ATOM 6925 N N . CYS C 2 99 ? -58.751 -22.148 29.282 1.00 27.98 ? 99 CYS K N 1 ATOM 6926 C CA . CYS C 2 99 ? -59.203 -23.410 28.716 1.00 26.56 ? 99 CYS K CA 1 ATOM 6927 C C . CYS C 2 99 ? -58.495 -23.688 27.394 1.00 26.30 ? 99 CYS K C 1 ATOM 6928 O O . CYS C 2 99 ? -58.683 -22.959 26.421 1.00 27.65 ? 99 CYS K O 1 ATOM 6929 C CB . CYS C 2 99 ? -60.716 -23.369 28.513 1.00 24.79 ? 99 CYS K CB 1 ATOM 6930 S SG . CYS C 2 99 ? -61.439 -24.913 27.945 1.00 20.71 ? 99 CYS K SG 1 ATOM 6931 N N . LYS C 2 100 ? -57.686 -24.744 27.362 1.00 23.07 ? 100 LYS K N 1 ATOM 6932 C CA . LYS C 2 100 ? -56.845 -25.030 26.201 1.00 21.77 ? 100 LYS K CA 1 ATOM 6933 C C . LYS C 2 100 ? -57.205 -26.352 25.526 1.00 23.24 ? 100 LYS K C 1 ATOM 6934 O O . LYS C 2 100 ? -57.790 -27.242 26.145 1.00 20.93 ? 100 LYS K O 1 ATOM 6935 C CB . LYS C 2 100 ? -55.366 -25.031 26.597 1.00 24.12 ? 100 LYS K CB 1 ATOM 6936 C CG . LYS C 2 100 ? -54.972 -23.877 27.505 1.00 29.07 ? 100 LYS K CG 1 ATOM 6937 C CD . LYS C 2 100 ? -53.602 -23.297 27.159 1.00 35.35 ? 100 LYS K CD 1 ATOM 6938 C CE . LYS C 2 100 ? -52.449 -24.105 27.732 1.00 35.29 ? 100 LYS K CE 1 ATOM 6939 N NZ . LYS C 2 100 ? -51.140 -23.495 27.360 1.00 28.52 1 100 LYS K NZ 1 ATOM 6940 N N . CYS C 2 101 ? -56.861 -26.467 24.247 1.00 22.27 ? 101 CYS K N 1 ATOM 6941 C CA . CYS C 2 101 ? -57.093 -27.699 23.508 1.00 22.31 ? 101 CYS K CA 1 ATOM 6942 C C . CYS C 2 101 ? -55.870 -28.593 23.645 1.00 27.15 ? 101 CYS K C 1 ATOM 6943 O O . CYS C 2 101 ? -54.738 -28.106 23.643 1.00 23.93 ? 101 CYS K O 1 ATOM 6944 C CB . CYS C 2 101 ? -57.377 -27.406 22.037 1.00 22.69 ? 101 CYS K CB 1 ATOM 6945 S SG . CYS C 2 101 ? -57.627 -28.894 21.038 1.00 37.92 ? 101 CYS K SG 1 ATOM 6946 N N . ALA C 2 102 ? -56.095 -29.899 23.759 1.00 26.22 ? 102 ALA K N 1 ATOM 6947 C CA . ALA C 2 102 ? -55.026 -30.807 24.162 1.00 27.26 ? 102 ALA K CA 1 ATOM 6948 C C . ALA C 2 102 ? -54.870 -32.024 23.264 1.00 21.07 ? 102 ALA K C 1 ATOM 6949 O O . ALA C 2 102 ? -55.669 -32.955 23.312 1.00 18.65 ? 102 ALA K O 1 ATOM 6950 C CB . ALA C 2 102 ? -55.222 -31.242 25.609 1.00 32.62 ? 102 ALA K CB 1 ATOM 6951 N N . LEU C 2 103 ? -53.810 -32.014 22.468 1.00 21.38 ? 103 LEU K N 1 ATOM 6952 C CA . LEU C 2 103 ? -53.530 -33.100 21.549 1.00 25.07 ? 103 LEU K CA 1 ATOM 6953 C C . LEU C 2 103 ? -52.737 -34.180 22.267 1.00 32.20 ? 103 LEU K C 1 ATOM 6954 O O . LEU C 2 103 ? -51.984 -33.888 23.196 1.00 33.35 ? 103 LEU K O 1 ATOM 6955 C CB . LEU C 2 103 ? -52.725 -32.578 20.358 1.00 23.16 ? 103 LEU K CB 1 ATOM 6956 C CG . LEU C 2 103 ? -52.909 -31.092 20.044 1.00 22.12 ? 103 LEU K CG 1 ATOM 6957 C CD1 . LEU C 2 103 ? -51.722 -30.559 19.266 1.00 22.24 ? 103 LEU K CD1 1 ATOM 6958 C CD2 . LEU C 2 103 ? -54.205 -30.850 19.281 1.00 21.89 ? 103 LEU K CD2 1 ATOM 6959 N N . LYS C 2 104 ? -52.906 -35.425 21.830 1.00 36.49 ? 104 LYS K N 1 ATOM 6960 C CA . LYS C 2 104 ? -52.148 -36.546 22.378 1.00 31.99 ? 104 LYS K CA 1 ATOM 6961 C C . LYS C 2 104 ? -50.966 -36.901 21.487 1.00 32.32 ? 104 LYS K C 1 ATOM 6962 O O . LYS C 2 104 ? -51.122 -37.602 20.489 1.00 28.26 ? 104 LYS K O 1 ATOM 6963 C CB . LYS C 2 104 ? -53.042 -37.774 22.560 1.00 26.25 ? 104 LYS K CB 1 ATOM 6964 C CG . LYS C 2 104 ? -53.724 -37.864 23.922 1.00 38.57 ? 104 LYS K CG 1 ATOM 6965 C CD . LYS C 2 104 ? -54.681 -36.699 24.171 1.00 42.89 ? 104 LYS K CD 1 ATOM 6966 C CE . LYS C 2 104 ? -55.172 -36.686 25.615 1.00 49.73 ? 104 LYS K CE 1 ATOM 6967 N NZ . LYS C 2 104 ? -56.095 -35.547 25.893 1.00 56.54 1 104 LYS K NZ 1 ATOM 6968 N N . THR C 2 105 ? -49.787 -36.406 21.855 1.00 42.80 ? 105 THR K N 1 ATOM 6969 C CA . THR C 2 105 ? -48.554 -36.718 21.137 1.00 50.24 ? 105 THR K CA 1 ATOM 6970 C C . THR C 2 105 ? -47.334 -36.469 22.026 1.00 59.76 ? 105 THR K C 1 ATOM 6971 O O . THR C 2 105 ? -47.468 -36.245 23.232 1.00 57.43 ? 105 THR K O 1 ATOM 6972 C CB . THR C 2 105 ? -48.423 -35.890 19.841 1.00 45.68 ? 105 THR K CB 1 ATOM 6973 O OG1 . THR C 2 105 ? -47.268 -36.322 19.110 1.00 51.88 ? 105 THR K OG1 1 ATOM 6974 C CG2 . THR C 2 105 ? -48.300 -34.400 20.158 1.00 39.05 ? 105 THR K CG2 1 ATOM 6975 N N . GLY C 2 106 ? -46.146 -36.511 21.429 1.00 61.13 ? 106 GLY K N 1 ATOM 6976 C CA . GLY C 2 106 ? -44.917 -36.244 22.156 1.00 62.29 ? 106 GLY K CA 1 ATOM 6977 C C . GLY C 2 106 ? -44.538 -34.775 22.130 1.00 57.60 ? 106 GLY K C 1 ATOM 6978 O O . GLY C 2 106 ? -44.971 -34.029 21.251 1.00 49.56 ? 106 GLY K O 1 ATOM 6979 N N . LEU C 2 107 ? -43.730 -34.357 23.101 1.00 60.38 ? 107 LEU K N 1 ATOM 6980 C CA . LEU C 2 107 ? -43.260 -32.975 23.159 1.00 61.18 ? 107 LEU K CA 1 ATOM 6981 C C . LEU C 2 107 ? -41.981 -32.787 22.348 1.00 60.22 ? 107 LEU K C 1 ATOM 6982 O O . LEU C 2 107 ? -41.886 -33.240 21.206 1.00 56.64 ? 107 LEU K O 1 ATOM 6983 C CB . LEU C 2 107 ? -43.042 -32.535 24.609 1.00 57.49 ? 107 LEU K CB 1 ATOM 6984 C CG . LEU C 2 107 ? -44.297 -32.138 25.393 1.00 49.20 ? 107 LEU K CG 1 ATOM 6985 C CD1 . LEU C 2 107 ? -43.980 -31.951 26.868 1.00 44.29 ? 107 LEU K CD1 1 ATOM 6986 C CD2 . LEU C 2 107 ? -44.904 -30.867 24.817 1.00 48.76 ? 107 LEU K CD2 1 HETATM 6987 C C1 . NAG D 3 . ? -40.492 -21.733 5.304 1.00 20.56 ? 2001 NAG A C1 1 HETATM 6988 C C2 . NAG D 3 . ? -41.333 -21.146 6.450 1.00 22.97 ? 2001 NAG A C2 1 HETATM 6989 C C3 . NAG D 3 . ? -40.640 -19.926 7.061 1.00 25.16 ? 2001 NAG A C3 1 HETATM 6990 C C4 . NAG D 3 . ? -39.199 -20.240 7.437 1.00 27.59 ? 2001 NAG A C4 1 HETATM 6991 C C5 . NAG D 3 . ? -38.464 -20.824 6.234 1.00 20.99 ? 2001 NAG A C5 1 HETATM 6992 C C6 . NAG D 3 . ? -37.051 -21.249 6.551 1.00 18.88 ? 2001 NAG A C6 1 HETATM 6993 C C7 . NAG D 3 . ? -43.747 -21.528 6.285 1.00 24.49 ? 2001 NAG A C7 1 HETATM 6994 C C8 . NAG D 3 . ? -45.047 -21.021 5.749 1.00 21.43 ? 2001 NAG A C8 1 HETATM 6995 N N2 . NAG D 3 . ? -42.668 -20.794 5.996 1.00 23.44 ? 2001 NAG A N2 1 HETATM 6996 O O3 . NAG D 3 . ? -41.338 -19.487 8.220 1.00 23.87 ? 2001 NAG A O3 1 HETATM 6997 O O4 . NAG D 3 . ? -38.561 -19.029 7.839 1.00 31.34 ? 2001 NAG A O4 1 HETATM 6998 O O5 . NAG D 3 . ? -39.148 -21.996 5.771 1.00 20.93 ? 2001 NAG A O5 1 HETATM 6999 O O6 . NAG D 3 . ? -37.013 -22.562 7.091 1.00 16.02 ? 2001 NAG A O6 1 HETATM 7000 O O7 . NAG D 3 . ? -43.674 -22.560 6.948 1.00 31.07 ? 2001 NAG A O7 1 HETATM 7001 C C1 . NAG E 3 . ? -38.184 -18.975 9.247 1.00 28.96 ? 2002 NAG A C1 1 HETATM 7002 C C2 . NAG E 3 . ? -37.007 -18.035 9.306 1.00 27.45 ? 2002 NAG A C2 1 HETATM 7003 C C3 . NAG E 3 . ? -36.458 -17.986 10.720 1.00 24.87 ? 2002 NAG A C3 1 HETATM 7004 C C4 . NAG E 3 . ? -37.556 -17.699 11.738 1.00 26.91 ? 2002 NAG A C4 1 HETATM 7005 C C5 . NAG E 3 . ? -38.855 -18.483 11.482 1.00 37.89 ? 2002 NAG A C5 1 HETATM 7006 C C6 . NAG E 3 . ? -40.055 -17.878 12.185 1.00 46.81 ? 2002 NAG A C6 1 HETATM 7007 C C7 . NAG E 3 . ? -35.282 -17.596 7.608 1.00 30.49 ? 2002 NAG A C7 1 HETATM 7008 C C8 . NAG E 3 . ? -35.621 -16.154 7.776 1.00 27.42 ? 2002 NAG A C8 1 HETATM 7009 N N2 . NAG E 3 . ? -35.973 -18.449 8.369 1.00 32.09 ? 2002 NAG A N2 1 HETATM 7010 O O3 . NAG E 3 . ? -35.480 -16.958 10.799 1.00 30.73 ? 2002 NAG A O3 1 HETATM 7011 O O4 . NAG E 3 . ? -37.042 -18.012 13.030 1.00 23.97 ? 2002 NAG A O4 1 HETATM 7012 O O5 . NAG E 3 . ? -39.196 -18.500 10.085 1.00 35.19 ? 2002 NAG A O5 1 HETATM 7013 O O6 . NAG E 3 . ? -40.293 -18.427 13.476 1.00 49.54 ? 2002 NAG A O6 1 HETATM 7014 O O7 . NAG E 3 . ? -34.417 -17.980 6.816 1.00 35.89 ? 2002 NAG A O7 1 HETATM 7015 C C1 . BMA F 4 . ? -37.063 -16.853 13.867 1.00 24.25 ? 2003 BMA A C1 1 HETATM 7016 C C2 . BMA F 4 . ? -37.564 -17.209 15.274 1.00 29.91 ? 2003 BMA A C2 1 HETATM 7017 C C3 . BMA F 4 . ? -37.909 -15.890 15.888 1.00 34.00 ? 2003 BMA A C3 1 HETATM 7018 C C4 . BMA F 4 . ? -36.617 -15.042 16.031 1.00 29.02 ? 2003 BMA A C4 1 HETATM 7019 C C5 . BMA F 4 . ? -35.981 -14.816 14.613 1.00 24.09 ? 2003 BMA A C5 1 HETATM 7020 C C6 . BMA F 4 . ? -34.587 -14.162 14.677 1.00 25.26 ? 2003 BMA A C6 1 HETATM 7021 O O2 . BMA F 4 . ? -36.518 -17.738 16.054 1.00 29.07 ? 2003 BMA A O2 1 HETATM 7022 O O3 . BMA F 4 . ? -38.784 -15.930 17.085 1.00 36.69 ? 2003 BMA A O3 1 HETATM 7023 O O4 . BMA F 4 . ? -36.918 -13.795 16.617 1.00 35.38 ? 2003 BMA A O4 1 HETATM 7024 O O5 . BMA F 4 . ? -35.866 -16.093 13.914 1.00 20.44 ? 2003 BMA A O5 1 HETATM 7025 O O6 . BMA F 4 . ? -34.284 -13.477 13.450 1.00 15.10 ? 2003 BMA A O6 1 HETATM 7026 C C1 . BMA G 4 . ? -38.477 -16.833 18.161 1.00 32.79 ? 2004 BMA A C1 1 HETATM 7027 C C2 . BMA G 4 . ? -38.013 -15.921 19.266 1.00 41.16 ? 2004 BMA A C2 1 HETATM 7028 C C3 . BMA G 4 . ? -38.809 -16.166 20.586 1.00 38.98 ? 2004 BMA A C3 1 HETATM 7029 C C4 . BMA G 4 . ? -39.060 -17.668 20.899 1.00 36.14 ? 2004 BMA A C4 1 HETATM 7030 C C5 . BMA G 4 . ? -39.397 -18.482 19.651 1.00 37.82 ? 2004 BMA A C5 1 HETATM 7031 C C6 . BMA G 4 . ? -40.644 -19.327 19.873 1.00 38.51 ? 2004 BMA A C6 1 HETATM 7032 O O2 . BMA G 4 . ? -38.240 -14.573 18.861 1.00 43.41 ? 2004 BMA A O2 1 HETATM 7033 O O3 . BMA G 4 . ? -40.016 -15.381 20.695 1.00 30.59 ? 2004 BMA A O3 1 HETATM 7034 O O4 . BMA G 4 . ? -37.921 -18.232 21.535 1.00 40.90 ? 2004 BMA A O4 1 HETATM 7035 O O5 . BMA G 4 . ? -39.611 -17.588 18.540 1.00 38.03 ? 2004 BMA A O5 1 HETATM 7036 O O6 . BMA G 4 . ? -40.769 -20.259 18.813 1.00 43.97 ? 2004 BMA A O6 1 HETATM 7037 C C1 . MAN H 5 . ? -39.691 -14.193 21.438 1.00 31.20 ? 2005 MAN A C1 1 HETATM 7038 C C2 . MAN H 5 . ? -40.801 -13.817 22.456 1.00 39.28 ? 2005 MAN A C2 1 HETATM 7039 C C3 . MAN H 5 . ? -41.911 -12.939 21.814 1.00 36.22 ? 2005 MAN A C3 1 HETATM 7040 C C4 . MAN H 5 . ? -41.343 -11.840 20.875 1.00 38.72 ? 2005 MAN A C4 1 HETATM 7041 C C5 . MAN H 5 . ? -40.363 -12.454 19.864 1.00 33.23 ? 2005 MAN A C5 1 HETATM 7042 C C6 . MAN H 5 . ? -39.713 -11.403 18.964 1.00 30.23 ? 2005 MAN A C6 1 HETATM 7043 O O2 . MAN H 5 . ? -40.280 -13.077 23.579 1.00 46.15 ? 2005 MAN A O2 1 HETATM 7044 O O3 . MAN H 5 . ? -42.750 -12.350 22.809 1.00 29.01 ? 2005 MAN A O3 1 HETATM 7045 O O4 . MAN H 5 . ? -42.406 -11.181 20.173 1.00 32.21 ? 2005 MAN A O4 1 HETATM 7046 O O5 . MAN H 5 . ? -39.303 -13.134 20.581 1.00 30.19 ? 2005 MAN A O5 1 HETATM 7047 O O6 . MAN H 5 . ? -39.376 -12.002 17.711 1.00 30.02 ? 2005 MAN A O6 1 HETATM 7048 C C1 . NAG I 3 . ? -69.127 -40.498 -5.193 1.00 55.00 ? 2006 NAG A C1 1 HETATM 7049 C C2 . NAG I 3 . ? -69.527 -41.558 -6.224 1.00 64.75 ? 2006 NAG A C2 1 HETATM 7050 C C3 . NAG I 3 . ? -70.097 -42.793 -5.527 1.00 63.64 ? 2006 NAG A C3 1 HETATM 7051 C C4 . NAG I 3 . ? -69.133 -43.292 -4.458 1.00 63.10 ? 2006 NAG A C4 1 HETATM 7052 C C5 . NAG I 3 . ? -68.792 -42.157 -3.500 1.00 50.33 ? 2006 NAG A C5 1 HETATM 7053 C C6 . NAG I 3 . ? -67.791 -42.556 -2.442 1.00 40.98 ? 2006 NAG A C6 1 HETATM 7054 C C7 . NAG I 3 . ? -70.227 -40.892 -8.482 1.00 62.35 ? 2006 NAG A C7 1 HETATM 7055 C C8 . NAG I 3 . ? -71.328 -40.305 -9.315 1.00 66.59 ? 2006 NAG A C8 1 HETATM 7056 N N2 . NAG I 3 . ? -70.485 -41.018 -7.175 1.00 60.10 ? 2006 NAG A N2 1 HETATM 7057 O O3 . NAG I 3 . ? -70.321 -43.817 -6.490 1.00 59.48 ? 2006 NAG A O3 1 HETATM 7058 O O4 . NAG I 3 . ? -69.716 -44.361 -3.722 1.00 75.74 ? 2006 NAG A O4 1 HETATM 7059 O O5 . NAG I 3 . ? -68.217 -41.069 -4.239 1.00 57.46 ? 2006 NAG A O5 1 HETATM 7060 O O6 . NAG I 3 . ? -67.985 -43.904 -2.035 1.00 36.61 ? 2006 NAG A O6 1 HETATM 7061 O O7 . NAG I 3 . ? -69.154 -41.241 -8.970 1.00 48.57 ? 2006 NAG A O7 1 HETATM 7062 C C1 . NAG J 3 . ? -77.485 -20.148 33.718 1.00 33.78 ? 2007 NAG A C1 1 HETATM 7063 C C2 . NAG J 3 . ? -76.154 -20.795 34.088 1.00 33.69 ? 2007 NAG A C2 1 HETATM 7064 C C3 . NAG J 3 . ? -76.370 -22.245 34.512 1.00 30.63 ? 2007 NAG A C3 1 HETATM 7065 C C4 . NAG J 3 . ? -77.438 -22.333 35.595 1.00 30.78 ? 2007 NAG A C4 1 HETATM 7066 C C5 . NAG J 3 . ? -78.702 -21.599 35.157 1.00 29.89 ? 2007 NAG A C5 1 HETATM 7067 C C6 . NAG J 3 . ? -79.752 -21.537 36.239 1.00 35.65 ? 2007 NAG A C6 1 HETATM 7068 C C7 . NAG J 3 . ? -74.170 -19.889 32.971 1.00 41.75 ? 2007 NAG A C7 1 HETATM 7069 C C8 . NAG J 3 . ? -73.306 -19.934 31.746 1.00 39.82 ? 2007 NAG A C8 1 HETATM 7070 N N2 . NAG J 3 . ? -75.216 -20.721 32.980 1.00 32.98 ? 2007 NAG A N2 1 HETATM 7071 O O3 . NAG J 3 . ? -75.141 -22.776 34.995 1.00 28.82 ? 2007 NAG A O3 1 HETATM 7072 O O4 . NAG J 3 . ? -77.763 -23.695 35.845 1.00 34.60 ? 2007 NAG A O4 1 HETATM 7073 O O5 . NAG J 3 . ? -78.382 -20.244 34.813 1.00 33.18 ? 2007 NAG A O5 1 HETATM 7074 O O6 . NAG J 3 . ? -80.067 -22.836 36.720 1.00 49.94 ? 2007 NAG A O6 1 HETATM 7075 O O7 . NAG J 3 . ? -73.931 -19.134 33.911 1.00 43.47 ? 2007 NAG A O7 1 HETATM 7076 C C1 . NAG K 3 . ? -31.184 -43.723 23.384 1.00 35.45 ? 2008 NAG A C1 1 HETATM 7077 C C2 . NAG K 3 . ? -32.439 -43.772 24.249 1.00 38.23 ? 2008 NAG A C2 1 HETATM 7078 C C3 . NAG K 3 . ? -33.116 -45.135 24.127 1.00 43.53 ? 2008 NAG A C3 1 HETATM 7079 C C4 . NAG K 3 . ? -33.308 -45.548 22.671 1.00 46.05 ? 2008 NAG A C4 1 HETATM 7080 C C5 . NAG K 3 . ? -32.049 -45.308 21.835 1.00 43.48 ? 2008 NAG A C5 1 HETATM 7081 C C6 . NAG K 3 . ? -32.300 -45.452 20.350 1.00 53.24 ? 2008 NAG A C6 1 HETATM 7082 C C7 . NAG K 3 . ? -31.982 -42.244 26.116 1.00 34.21 ? 2008 NAG A C7 1 HETATM 7083 C C8 . NAG K 3 . ? -31.677 -42.135 27.579 1.00 32.31 ? 2008 NAG A C8 1 HETATM 7084 N N2 . NAG K 3 . ? -32.134 -43.484 25.641 1.00 35.18 ? 2008 NAG A N2 1 HETATM 7085 O O3 . NAG K 3 . ? -34.375 -45.086 24.789 1.00 37.18 ? 2008 NAG A O3 1 HETATM 7086 O O4 . NAG K 3 . ? -33.521 -46.954 22.647 1.00 61.54 ? 2008 NAG A O4 1 HETATM 7087 O O5 . NAG K 3 . ? -31.530 -43.986 22.041 1.00 37.96 ? 2008 NAG A O5 1 HETATM 7088 O O6 . NAG K 3 . ? -31.340 -44.742 19.579 1.00 53.85 ? 2008 NAG A O6 1 HETATM 7089 O O7 . NAG K 3 . ? -32.068 -41.255 25.393 1.00 26.52 ? 2008 NAG A O7 1 HETATM 7090 C C1 . NAG L 3 . ? -34.783 -47.451 22.155 1.00 61.85 ? 2009 NAG A C1 1 HETATM 7091 C C2 . NAG L 3 . ? -36.007 -46.582 22.444 1.00 60.95 ? 2009 NAG A C2 1 HETATM 7092 C C3 . NAG L 3 . ? -36.934 -46.558 21.226 1.00 66.17 ? 2009 NAG A C3 1 HETATM 7093 C C4 . NAG L 3 . ? -37.099 -47.954 20.633 1.00 68.99 ? 2009 NAG A C4 1 HETATM 7094 C C5 . NAG L 3 . ? -35.738 -48.554 20.282 1.00 67.46 ? 2009 NAG A C5 1 HETATM 7095 C C6 . NAG L 3 . ? -35.519 -48.718 18.796 1.00 65.42 ? 2009 NAG A C6 1 HETATM 7096 C C7 . NAG L 3 . ? -37.390 -46.276 24.467 1.00 60.81 ? 2009 NAG A C7 1 HETATM 7097 C C8 . NAG L 3 . ? -37.400 -44.809 24.147 1.00 57.28 ? 2009 NAG A C8 1 HETATM 7098 N N2 . NAG L 3 . ? -36.716 -47.064 23.620 1.00 63.16 ? 2009 NAG A N2 1 HETATM 7099 O O3 . NAG L 3 . ? -36.394 -45.674 20.251 1.00 78.18 ? 2009 NAG A O3 1 HETATM 7100 O O4 . NAG L 3 . ? -37.774 -48.810 21.548 1.00 68.39 ? 2009 NAG A O4 1 HETATM 7101 O O5 . NAG L 3 . ? -34.693 -47.697 20.760 1.00 57.44 ? 2009 NAG A O5 1 HETATM 7102 O O6 . NAG L 3 . ? -34.178 -49.096 18.514 1.00 56.11 ? 2009 NAG A O6 1 HETATM 7103 O O7 . NAG L 3 . ? -37.971 -46.730 25.449 1.00 59.54 ? 2009 NAG A O7 1 HETATM 7104 C C1 . NAG M 3 . ? -27.867 -31.936 31.222 1.00 25.65 ? 2010 NAG A C1 1 HETATM 7105 C C2 . NAG M 3 . ? -28.593 -30.915 32.097 1.00 27.74 ? 2010 NAG A C2 1 HETATM 7106 C C3 . NAG M 3 . ? -29.204 -31.600 33.317 1.00 36.11 ? 2010 NAG A C3 1 HETATM 7107 C C4 . NAG M 3 . ? -30.049 -32.800 32.906 1.00 32.56 ? 2010 NAG A C4 1 HETATM 7108 C C5 . NAG M 3 . ? -29.244 -33.708 31.978 1.00 25.45 ? 2010 NAG A C5 1 HETATM 7109 C C6 . NAG M 3 . ? -30.049 -34.855 31.419 1.00 29.46 ? 2010 NAG A C6 1 HETATM 7110 C C7 . NAG M 3 . ? -27.422 -28.777 31.766 1.00 43.81 ? 2010 NAG A C7 1 HETATM 7111 C C8 . NAG M 3 . ? -26.475 -27.782 32.370 1.00 46.58 ? 2010 NAG A C8 1 HETATM 7112 N N2 . NAG M 3 . ? -27.695 -29.851 32.515 1.00 37.40 ? 2010 NAG A N2 1 HETATM 7113 O O3 . NAG M 3 . ? -29.984 -30.653 34.040 1.00 45.63 ? 2010 NAG A O3 1 HETATM 7114 O O4 . NAG M 3 . ? -30.406 -33.569 34.051 1.00 39.65 ? 2010 NAG A O4 1 HETATM 7115 O O5 . NAG M 3 . ? -28.759 -32.960 30.856 1.00 20.51 ? 2010 NAG A O5 1 HETATM 7116 O O6 . NAG M 3 . ? -30.018 -35.973 32.294 1.00 39.99 ? 2010 NAG A O6 1 HETATM 7117 O O7 . NAG M 3 . ? -27.913 -28.616 30.650 1.00 36.80 ? 2010 NAG A O7 1 HETATM 7118 C C1 . NAG N 3 . ? -31.597 -33.174 34.771 1.00 37.19 ? 2011 NAG A C1 1 HETATM 7119 C C2 . NAG N 3 . ? -31.751 -34.141 35.922 1.00 44.96 ? 2011 NAG A C2 1 HETATM 7120 C C3 . NAG N 3 . ? -33.089 -33.917 36.617 1.00 57.39 ? 2011 NAG A C3 1 HETATM 7121 C C4 . NAG N 3 . ? -33.257 -32.451 37.008 1.00 62.04 ? 2011 NAG A C4 1 HETATM 7122 C C5 . NAG N 3 . ? -32.884 -31.496 35.865 1.00 52.04 ? 2011 NAG A C5 1 HETATM 7123 C C6 . NAG N 3 . ? -32.737 -30.063 36.323 1.00 53.40 ? 2011 NAG A C6 1 HETATM 7124 C C7 . NAG N 3 . ? -32.387 -36.118 34.584 1.00 37.23 ? 2011 NAG A C7 1 HETATM 7125 C C8 . NAG N 3 . ? -32.057 -37.548 34.279 1.00 41.80 ? 2011 NAG A C8 1 HETATM 7126 N N2 . NAG N 3 . ? -31.604 -35.522 35.490 1.00 36.10 ? 2011 NAG A N2 1 HETATM 7127 O O3 . NAG N 3 . ? -33.160 -34.737 37.778 1.00 60.11 ? 2011 NAG A O3 1 HETATM 7128 O O4 . NAG N 3 . ? -34.619 -32.225 37.357 1.00 66.75 ? 2011 NAG A O4 1 HETATM 7129 O O5 . NAG N 3 . ? -31.628 -31.855 35.264 1.00 43.42 ? 2011 NAG A O5 1 HETATM 7130 O O6 . NAG N 3 . ? -33.933 -29.571 36.913 1.00 66.80 ? 2011 NAG A O6 1 HETATM 7131 O O7 . NAG N 3 . ? -33.321 -35.538 34.041 1.00 47.63 ? 2011 NAG A O7 1 HETATM 7132 C C1 . BMA O 4 . ? -34.810 -31.996 38.769 1.00 62.80 ? 2012 BMA A C1 1 HETATM 7133 C C2 . BMA O 4 . ? -36.264 -31.541 38.980 1.00 65.76 ? 2012 BMA A C2 1 HETATM 7134 C C3 . BMA O 4 . ? -36.492 -31.220 40.460 1.00 71.81 ? 2012 BMA A C3 1 HETATM 7135 C C4 . BMA O 4 . ? -36.031 -32.393 41.353 1.00 70.28 ? 2012 BMA A C4 1 HETATM 7136 C C5 . BMA O 4 . ? -34.568 -32.767 41.022 1.00 61.28 ? 2012 BMA A C5 1 HETATM 7137 C C6 . BMA O 4 . ? -34.069 -33.959 41.823 1.00 63.91 ? 2012 BMA A C6 1 HETATM 7138 O O2 . BMA O 4 . ? -37.164 -32.588 38.628 1.00 51.76 ? 2012 BMA A O2 1 HETATM 7139 O O3 . BMA O 4 . ? -37.857 -30.871 40.736 1.00 63.61 ? 2012 BMA A O3 1 HETATM 7140 O O4 . BMA O 4 . ? -36.139 -32.046 42.727 1.00 63.42 ? 2012 BMA A O4 1 HETATM 7141 O O5 . BMA O 4 . ? -34.469 -33.082 39.611 1.00 57.29 ? 2012 BMA A O5 1 HETATM 7142 O O6 . BMA O 4 . ? -34.944 -35.060 41.593 1.00 59.76 ? 2012 BMA A O6 1 HETATM 7143 C C1 . NAG P 3 . ? -87.258 -24.524 12.251 1.00 38.21 ? 2013 NAG A C1 1 HETATM 7144 C C2 . NAG P 3 . ? -87.890 -25.155 13.492 1.00 39.26 ? 2013 NAG A C2 1 HETATM 7145 C C3 . NAG P 3 . ? -88.098 -26.655 13.281 1.00 46.62 ? 2013 NAG A C3 1 HETATM 7146 C C4 . NAG P 3 . ? -88.861 -26.925 11.985 1.00 49.68 ? 2013 NAG A C4 1 HETATM 7147 C C5 . NAG P 3 . ? -88.195 -26.196 10.819 1.00 41.18 ? 2013 NAG A C5 1 HETATM 7148 C C6 . NAG P 3 . ? -88.984 -26.296 9.534 1.00 50.14 ? 2013 NAG A C6 1 HETATM 7149 C C7 . NAG P 3 . ? -87.421 -24.107 15.671 1.00 33.34 ? 2013 NAG A C7 1 HETATM 7150 C C8 . NAG P 3 . ? -88.759 -23.441 15.542 1.00 25.70 ? 2013 NAG A C8 1 HETATM 7151 N N2 . NAG P 3 . ? -87.065 -24.916 14.665 1.00 38.09 ? 2013 NAG A N2 1 HETATM 7152 O O3 . NAG P 3 . ? -88.790 -27.173 14.412 1.00 42.24 ? 2013 NAG A O3 1 HETATM 7153 O O4 . NAG P 3 . ? -88.860 -28.314 11.662 1.00 66.76 ? 2013 NAG A O4 1 HETATM 7154 O O5 . NAG P 3 . ? -88.066 -24.798 11.113 1.00 40.35 ? 2013 NAG A O5 1 HETATM 7155 O O6 . NAG P 3 . ? -88.215 -26.881 8.493 1.00 55.00 ? 2013 NAG A O6 1 HETATM 7156 O O7 . NAG P 3 . ? -86.692 -23.921 16.642 1.00 36.99 ? 2013 NAG A O7 1 HETATM 7157 C C1 . NAG Q 3 . ? -89.811 -29.145 12.376 1.00 74.19 ? 2014 NAG A C1 1 HETATM 7158 C C2 . NAG Q 3 . ? -90.866 -29.740 11.432 1.00 66.30 ? 2014 NAG A C2 1 HETATM 7159 C C3 . NAG Q 3 . ? -91.822 -30.645 12.209 1.00 68.54 ? 2014 NAG A C3 1 HETATM 7160 C C4 . NAG Q 3 . ? -91.039 -31.703 12.976 1.00 73.44 ? 2014 NAG A C4 1 HETATM 7161 C C5 . NAG Q 3 . ? -90.012 -31.027 13.880 1.00 75.02 ? 2014 NAG A C5 1 HETATM 7162 C C6 . NAG Q 3 . ? -89.136 -32.005 14.629 1.00 60.95 ? 2014 NAG A C6 1 HETATM 7163 C C7 . NAG Q 3 . ? -92.063 -28.844 9.484 1.00 78.12 ? 2014 NAG A C7 1 HETATM 7164 C C8 . NAG Q 3 . ? -92.796 -27.667 8.912 1.00 65.77 ? 2014 NAG A C8 1 HETATM 7165 N N2 . NAG Q 3 . ? -91.601 -28.699 10.732 1.00 69.18 ? 2014 NAG A N2 1 HETATM 7166 O O3 . NAG Q 3 . ? -92.736 -31.267 11.314 1.00 81.92 ? 2014 NAG A O3 1 HETATM 7167 O O4 . NAG Q 3 . ? -91.922 -32.500 13.759 1.00 73.26 ? 2014 NAG A O4 1 HETATM 7168 O O5 . NAG Q 3 . ? -89.139 -30.209 13.085 1.00 79.57 ? 2014 NAG A O5 1 HETATM 7169 O O6 . NAG Q 3 . ? -88.799 -31.523 15.924 1.00 47.04 ? 2014 NAG A O6 1 HETATM 7170 O O7 . NAG Q 3 . ? -91.898 -29.880 8.846 1.00 83.58 ? 2014 NAG A O7 1 HETATM 7171 C C1 . NAG R 3 . ? -57.985 -15.399 -13.649 1.00 35.25 ? 2015 NAG A C1 1 HETATM 7172 C C2 . NAG R 3 . ? -57.180 -14.121 -13.839 1.00 42.23 ? 2015 NAG A C2 1 HETATM 7173 C C3 . NAG R 3 . ? -57.374 -13.570 -15.256 1.00 49.68 ? 2015 NAG A C3 1 HETATM 7174 C C4 . NAG R 3 . ? -57.125 -14.654 -16.304 1.00 51.86 ? 2015 NAG A C4 1 HETATM 7175 C C5 . NAG R 3 . ? -57.925 -15.910 -15.963 1.00 41.20 ? 2015 NAG A C5 1 HETATM 7176 C C6 . NAG R 3 . ? -57.634 -17.068 -16.889 1.00 42.54 ? 2015 NAG A C6 1 HETATM 7177 C C7 . NAG R 3 . ? -56.680 -12.591 -11.987 1.00 42.22 ? 2015 NAG A C7 1 HETATM 7178 C C8 . NAG R 3 . ? -57.239 -11.582 -11.031 1.00 38.98 ? 2015 NAG A C8 1 HETATM 7179 N N2 . NAG R 3 . ? -57.552 -13.125 -12.847 1.00 36.61 ? 2015 NAG A N2 1 HETATM 7180 O O3 . NAG R 3 . ? -56.483 -12.473 -15.428 1.00 41.92 ? 2015 NAG A O3 1 HETATM 7181 O O4 . NAG R 3 . ? -57.537 -14.234 -17.603 1.00 48.88 ? 2015 NAG A O4 1 HETATM 7182 O O5 . NAG R 3 . ? -57.611 -16.347 -14.634 1.00 34.95 ? 2015 NAG A O5 1 HETATM 7183 O O6 . NAG R 3 . ? -58.096 -16.802 -18.206 1.00 44.79 ? 2015 NAG A O6 1 HETATM 7184 O O7 . NAG R 3 . ? -55.494 -12.913 -11.977 1.00 49.34 ? 2015 NAG A O7 1 HETATM 7185 C C1 . NAG S 3 . ? -56.629 -13.340 -18.293 1.00 53.01 ? 2016 NAG A C1 1 HETATM 7186 C C2 . NAG S 3 . ? -55.391 -14.047 -18.861 1.00 59.41 ? 2016 NAG A C2 1 HETATM 7187 C C3 . NAG S 3 . ? -55.359 -13.914 -20.383 1.00 66.33 ? 2016 NAG A C3 1 HETATM 7188 C C4 . NAG S 3 . ? -56.719 -14.237 -20.976 1.00 57.96 ? 2016 NAG A C4 1 HETATM 7189 C C5 . NAG S 3 . ? -57.746 -13.218 -20.491 1.00 63.62 ? 2016 NAG A C5 1 HETATM 7190 C C6 . NAG S 3 . ? -59.079 -13.832 -20.122 1.00 59.11 ? 2016 NAG A C6 1 HETATM 7191 C C7 . NAG S 3 . ? -53.234 -14.303 -17.718 1.00 60.87 ? 2016 NAG A C7 1 HETATM 7192 C C8 . NAG S 3 . ? -53.519 -15.777 -17.717 1.00 54.04 ? 2016 NAG A C8 1 HETATM 7193 N N2 . NAG S 3 . ? -54.172 -13.526 -18.276 1.00 60.07 ? 2016 NAG A N2 1 HETATM 7194 O O3 . NAG S 3 . ? -54.362 -14.777 -20.926 1.00 75.48 ? 2016 NAG A O3 1 HETATM 7195 O O4 . NAG S 3 . ? -56.653 -14.195 -22.398 1.00 48.88 ? 2016 NAG A O4 1 HETATM 7196 O O5 . NAG S 3 . ? -57.254 -12.518 -19.332 1.00 62.22 ? 2016 NAG A O5 1 HETATM 7197 O O6 . NAG S 3 . ? -60.092 -12.844 -19.994 1.00 49.54 ? 2016 NAG A O6 1 HETATM 7198 O O7 . NAG S 3 . ? -52.207 -13.839 -17.237 1.00 70.53 ? 2016 NAG A O7 1 HETATM 7199 C C1 . NAG T 3 . ? 0.309 -61.367 76.047 1.00 53.04 ? 2017 NAG A C1 1 HETATM 7200 C C2 . NAG T 3 . ? 0.354 -62.860 76.371 1.00 55.08 ? 2017 NAG A C2 1 HETATM 7201 C C3 . NAG T 3 . ? -1.000 -63.321 76.905 1.00 49.87 ? 2017 NAG A C3 1 HETATM 7202 C C4 . NAG T 3 . ? -1.443 -62.435 78.061 1.00 50.37 ? 2017 NAG A C4 1 HETATM 7203 C C5 . NAG T 3 . ? -1.390 -60.968 77.648 1.00 55.40 ? 2017 NAG A C5 1 HETATM 7204 C C6 . NAG T 3 . ? -1.718 -60.017 78.774 1.00 66.12 ? 2017 NAG A C6 1 HETATM 7205 C C7 . NAG T 3 . ? 2.003 -63.932 74.894 1.00 59.23 ? 2017 NAG A C7 1 HETATM 7206 C C8 . NAG T 3 . ? 2.208 -64.732 73.644 1.00 47.80 ? 2017 NAG A C8 1 HETATM 7207 N N2 . NAG T 3 . ? 0.734 -63.634 75.199 1.00 62.36 ? 2017 NAG A N2 1 HETATM 7208 O O3 . NAG T 3 . ? -0.925 -64.677 77.328 1.00 50.65 ? 2017 NAG A O3 1 HETATM 7209 O O4 . NAG T 3 . ? -2.783 -62.744 78.418 1.00 55.62 ? 2017 NAG A O4 1 HETATM 7210 O O5 . NAG T 3 . ? -0.068 -60.643 77.200 1.00 51.14 ? 2017 NAG A O5 1 HETATM 7211 O O6 . NAG T 3 . ? -2.634 -59.014 78.353 1.00 69.08 ? 2017 NAG A O6 1 HETATM 7212 O O7 . NAG T 3 . ? 2.944 -63.571 75.596 1.00 63.46 ? 2017 NAG A O7 1 HETATM 7213 C C1 . NAG U 3 . ? -2.843 -63.493 79.642 1.00 57.07 ? 2018 NAG A C1 1 HETATM 7214 C C2 . NAG U 3 . ? -4.141 -64.279 79.638 1.00 54.38 ? 2018 NAG A C2 1 HETATM 7215 C C3 . NAG U 3 . ? -4.321 -64.981 80.981 1.00 52.81 ? 2018 NAG A C3 1 HETATM 7216 C C4 . NAG U 3 . ? -3.098 -65.835 81.294 1.00 62.19 ? 2018 NAG A C4 1 HETATM 7217 C C5 . NAG U 3 . ? -1.817 -65.007 81.178 1.00 61.69 ? 2018 NAG A C5 1 HETATM 7218 C C6 . NAG U 3 . ? -0.562 -65.836 81.323 1.00 56.92 ? 2018 NAG A C6 1 HETATM 7219 C C7 . NAG U 3 . ? -5.824 -63.285 78.136 1.00 54.98 ? 2018 NAG A C7 1 HETATM 7220 C C8 . NAG U 3 . ? -5.230 -64.132 77.048 1.00 51.75 ? 2018 NAG A C8 1 HETATM 7221 N N2 . NAG U 3 . ? -5.269 -63.406 79.351 1.00 59.19 ? 2018 NAG A N2 1 HETATM 7222 O O3 . NAG U 3 . ? -5.485 -65.799 80.957 1.00 48.29 ? 2018 NAG A O3 1 HETATM 7223 O O4 . NAG U 3 . ? -3.200 -66.364 82.611 1.00 68.65 ? 2018 NAG A O4 1 HETATM 7224 O O5 . NAG U 3 . ? -1.750 -64.377 79.888 1.00 64.79 ? 2018 NAG A O5 1 HETATM 7225 O O6 . NAG U 3 . ? -0.624 -67.018 80.535 1.00 50.13 ? 2018 NAG A O6 1 HETATM 7226 O O7 . NAG U 3 . ? -6.772 -62.532 77.927 1.00 39.77 ? 2018 NAG A O7 1 HETATM 7227 C C1 . NAG V 3 . ? -29.807 -18.906 -3.718 1.00 45.48 ? 2019 NAG A C1 1 HETATM 7228 C C2 . NAG V 3 . ? -28.877 -19.416 -4.852 1.00 49.66 ? 2019 NAG A C2 1 HETATM 7229 C C3 . NAG V 3 . ? -28.690 -18.349 -5.947 1.00 54.53 ? 2019 NAG A C3 1 HETATM 7230 C C4 . NAG V 3 . ? -30.033 -17.774 -6.380 1.00 55.96 ? 2019 NAG A C4 1 HETATM 7231 C C5 . NAG V 3 . ? -30.769 -17.265 -5.153 1.00 50.63 ? 2019 NAG A C5 1 HETATM 7232 C C6 . NAG V 3 . ? -32.109 -16.646 -5.460 1.00 49.84 ? 2019 NAG A C6 1 HETATM 7233 C C7 . NAG V 3 . ? -26.807 -19.208 -3.485 1.00 46.16 ? 2019 NAG A C7 1 HETATM 7234 C C8 . NAG V 3 . ? -25.532 -19.884 -3.102 1.00 46.70 ? 2019 NAG A C8 1 HETATM 7235 N N2 . NAG V 3 . ? -27.589 -19.882 -4.345 1.00 44.77 ? 2019 NAG A N2 1 HETATM 7236 O O3 . NAG V 3 . ? -28.064 -18.931 -7.085 1.00 59.49 ? 2019 NAG A O3 1 HETATM 7237 O O4 . NAG V 3 . ? -29.853 -16.709 -7.309 1.00 61.28 ? 2019 NAG A O4 1 HETATM 7238 O O5 . NAG V 3 . ? -31.011 -18.372 -4.279 1.00 44.84 ? 2019 NAG A O5 1 HETATM 7239 O O6 . NAG V 3 . ? -32.520 -15.817 -4.382 1.00 55.85 ? 2019 NAG A O6 1 HETATM 7240 O O7 . NAG V 3 . ? -27.111 -18.101 -3.037 1.00 52.56 ? 2019 NAG A O7 1 HETATM 7241 C C1 . NAG W 3 . ? -30.197 -17.123 -8.659 1.00 61.93 ? 2020 NAG A C1 1 HETATM 7242 C C2 . NAG W 3 . ? -29.571 -16.181 -9.689 1.00 62.73 ? 2020 NAG A C2 1 HETATM 7243 C C3 . NAG W 3 . ? -29.989 -16.581 -11.102 1.00 58.99 ? 2020 NAG A C3 1 HETATM 7244 C C4 . NAG W 3 . ? -29.741 -18.063 -11.352 1.00 63.77 ? 2020 NAG A C4 1 HETATM 7245 C C5 . NAG W 3 . ? -30.306 -18.925 -10.217 1.00 60.42 ? 2020 NAG A C5 1 HETATM 7246 C C6 . NAG W 3 . ? -29.898 -20.379 -10.311 1.00 52.28 ? 2020 NAG A C6 1 HETATM 7247 C C7 . NAG W 3 . ? -29.314 -14.029 -8.537 1.00 62.30 ? 2020 NAG A C7 1 HETATM 7248 C C8 . NAG W 3 . ? -29.820 -12.623 -8.412 1.00 60.49 ? 2020 NAG A C8 1 HETATM 7249 N N2 . NAG W 3 . ? -29.942 -14.800 -9.430 1.00 61.20 ? 2020 NAG A N2 1 HETATM 7250 O O3 . NAG W 3 . ? -29.235 -15.810 -12.031 1.00 49.46 ? 2020 NAG A O3 1 HETATM 7251 O O4 . NAG W 3 . ? -30.351 -18.418 -12.590 1.00 52.33 ? 2020 NAG A O4 1 HETATM 7252 O O5 . NAG W 3 . ? -29.825 -18.456 -8.948 1.00 52.96 ? 2020 NAG A O5 1 HETATM 7253 O O6 . NAG W 3 . ? -29.962 -20.862 -11.646 1.00 66.48 ? 2020 NAG A O6 1 HETATM 7254 O O7 . NAG W 3 . ? -28.387 -14.451 -7.854 1.00 50.64 ? 2020 NAG A O7 1 HETATM 7255 C C1 . NAG X 3 . ? -17.890 -47.953 25.627 1.00 55.52 ? 2021 NAG A C1 1 HETATM 7256 C C2 . NAG X 3 . ? -17.438 -48.217 24.176 1.00 57.23 ? 2021 NAG A C2 1 HETATM 7257 C C3 . NAG X 3 . ? -16.651 -49.530 24.060 1.00 68.99 ? 2021 NAG A C3 1 HETATM 7258 C C4 . NAG X 3 . ? -15.567 -49.626 25.124 1.00 68.75 ? 2021 NAG A C4 1 HETATM 7259 C C5 . NAG X 3 . ? -16.199 -49.388 26.491 1.00 70.44 ? 2021 NAG A C5 1 HETATM 7260 C C6 . NAG X 3 . ? -15.221 -49.456 27.640 1.00 80.57 ? 2021 NAG A C6 1 HETATM 7261 C C7 . NAG X 3 . ? -19.569 -49.150 23.337 1.00 64.66 ? 2021 NAG A C7 1 HETATM 7262 C C8 . NAG X 3 . ? -20.653 -48.993 22.310 1.00 65.84 ? 2021 NAG A C8 1 HETATM 7263 N N2 . NAG X 3 . ? -18.586 -48.240 23.285 1.00 58.90 ? 2021 NAG A N2 1 HETATM 7264 O O3 . NAG X 3 . ? -16.067 -49.597 22.765 1.00 83.29 ? 2021 NAG A O3 1 HETATM 7265 O O4 . NAG X 3 . ? -14.951 -50.910 25.074 1.00 75.57 ? 2021 NAG A O4 1 HETATM 7266 O O5 . NAG X 3 . ? -16.778 -48.077 26.514 1.00 62.09 ? 2021 NAG A O5 1 HETATM 7267 O O6 . NAG X 3 . ? -15.076 -50.785 28.122 1.00 77.62 ? 2021 NAG A O6 1 HETATM 7268 O O7 . NAG X 3 . ? -19.594 -50.046 24.179 1.00 57.18 ? 2021 NAG A O7 1 HETATM 7269 C C1 . NAG Y 3 . ? -73.256 -0.538 2.771 1.00 47.52 ? 2022 NAG A C1 1 HETATM 7270 C C2 . NAG Y 3 . ? -74.695 -0.132 3.187 1.00 44.07 ? 2022 NAG A C2 1 HETATM 7271 C C3 . NAG Y 3 . ? -74.747 1.199 3.966 1.00 50.50 ? 2022 NAG A C3 1 HETATM 7272 C C4 . NAG Y 3 . ? -73.794 2.271 3.439 1.00 53.62 ? 2022 NAG A C4 1 HETATM 7273 C C5 . NAG Y 3 . ? -72.609 1.664 2.705 1.00 48.98 ? 2022 NAG A C5 1 HETATM 7274 C C6 . NAG Y 3 . ? -71.343 2.460 2.900 1.00 54.34 ? 2022 NAG A C6 1 HETATM 7275 C C7 . NAG Y 3 . ? -76.356 -1.152 1.709 1.00 51.60 ? 2022 NAG A C7 1 HETATM 7276 C C8 . NAG Y 3 . ? -76.216 -2.370 2.573 1.00 33.80 ? 2022 NAG A C8 1 HETATM 7277 N N2 . NAG Y 3 . ? -75.601 -0.104 2.052 1.00 48.06 ? 2022 NAG A N2 1 HETATM 7278 O O3 . NAG Y 3 . ? -74.501 0.950 5.343 1.00 52.12 ? 2022 NAG A O3 1 HETATM 7279 O O4 . NAG Y 3 . ? -74.470 3.249 2.655 1.00 53.69 ? 2022 NAG A O4 1 HETATM 7280 O O5 . NAG Y 3 . ? -72.365 0.367 3.248 1.00 46.33 ? 2022 NAG A O5 1 HETATM 7281 O O6 . NAG Y 3 . ? -70.348 2.111 1.948 1.00 54.04 ? 2022 NAG A O6 1 HETATM 7282 O O7 . NAG Y 3 . ? -77.123 -1.117 0.750 1.00 63.44 ? 2022 NAG A O7 1 HETATM 7283 C C1 . NAG Z 3 . ? -3.471 -63.952 62.222 1.00 70.17 ? 2023 NAG A C1 1 HETATM 7284 C C2 . NAG Z 3 . ? -4.512 -64.152 61.115 1.00 67.50 ? 2023 NAG A C2 1 HETATM 7285 C C3 . NAG Z 3 . ? -4.057 -65.248 60.140 1.00 63.97 ? 2023 NAG A C3 1 HETATM 7286 C C4 . NAG Z 3 . ? -2.624 -65.009 59.671 1.00 69.67 ? 2023 NAG A C4 1 HETATM 7287 C C5 . NAG Z 3 . ? -1.692 -64.731 60.848 1.00 61.84 ? 2023 NAG A C5 1 HETATM 7288 C C6 . NAG Z 3 . ? -0.301 -64.324 60.420 1.00 47.88 ? 2023 NAG A C6 1 HETATM 7289 C C7 . NAG Z 3 . ? -6.948 -64.541 60.990 1.00 57.41 ? 2023 NAG A C7 1 HETATM 7290 C C8 . NAG Z 3 . ? -8.179 -64.877 61.780 1.00 43.80 ? 2023 NAG A C8 1 HETATM 7291 N N2 . NAG Z 3 . ? -5.811 -64.473 61.689 1.00 60.61 ? 2023 NAG A N2 1 HETATM 7292 O O3 . NAG Z 3 . ? -4.933 -65.269 59.016 1.00 39.62 ? 2023 NAG A O3 1 HETATM 7293 O O4 . NAG Z 3 . ? -2.130 -66.159 58.991 1.00 84.41 ? 2023 NAG A O4 1 HETATM 7294 O O5 . NAG Z 3 . ? -2.209 -63.654 61.641 1.00 69.86 ? 2023 NAG A O5 1 HETATM 7295 O O6 . NAG Z 3 . ? 0.080 -64.953 59.204 1.00 41.59 ? 2023 NAG A O6 1 HETATM 7296 O O7 . NAG Z 3 . ? -6.982 -64.355 59.776 1.00 60.36 ? 2023 NAG A O7 1 HETATM 7297 N N1 . EPE AA 6 . ? -69.949 -31.405 12.279 1.00 36.46 ? 2024 EPE A N1 1 HETATM 7298 C C2 . EPE AA 6 . ? -69.254 -32.693 12.436 1.00 47.69 ? 2024 EPE A C2 1 HETATM 7299 C C3 . EPE AA 6 . ? -69.112 -33.318 11.053 1.00 45.19 ? 2024 EPE A C3 1 HETATM 7300 N N4 . EPE AA 6 . ? -70.045 -32.720 10.112 1.00 35.89 ? 2024 EPE A N4 1 HETATM 7301 C C5 . EPE AA 6 . ? -71.379 -32.358 10.557 1.00 28.51 ? 2024 EPE A C5 1 HETATM 7302 C C6 . EPE AA 6 . ? -71.349 -31.660 11.910 1.00 28.46 ? 2024 EPE A C6 1 HETATM 7303 C C7 . EPE AA 6 . ? -69.794 -32.856 8.691 1.00 25.69 ? 2024 EPE A C7 1 HETATM 7304 C C8 . EPE AA 6 . ? -70.812 -33.765 8.017 1.00 27.70 ? 2024 EPE A C8 1 HETATM 7305 O O8 . EPE AA 6 . ? -70.891 -34.976 8.735 1.00 39.39 ? 2024 EPE A O8 1 HETATM 7306 C C9 . EPE AA 6 . ? -69.872 -30.617 13.520 1.00 33.94 ? 2024 EPE A C9 1 HETATM 7307 C C10 . EPE AA 6 . ? -70.876 -31.115 14.553 1.00 31.45 ? 2024 EPE A C10 1 HETATM 7308 S S . EPE AA 6 . ? -71.775 -29.743 15.321 1.00 40.29 ? 2024 EPE A S 1 HETATM 7309 O O1S . EPE AA 6 . ? -73.054 -30.244 15.822 1.00 39.35 ? 2024 EPE A O1S 1 HETATM 7310 O O2S . EPE AA 6 . ? -70.998 -29.214 16.436 1.00 34.84 ? 2024 EPE A O2S 1 HETATM 7311 O O3S . EPE AA 6 . ? -72.007 -28.673 14.345 1.00 27.15 ? 2024 EPE A O3S 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 SER 1 28 28 SER SER A . n A 1 2 PHE 2 29 29 PHE PHE A . n A 1 3 GLY 3 30 30 GLY GLY A . n A 1 4 ARG 4 31 31 ARG ARG A . n A 1 5 ASP 5 32 32 ASP ASP A . n A 1 6 ALA 6 33 33 ALA ALA A . n A 1 7 CYS 7 34 34 CYS CYS A . n A 1 8 SER 8 35 35 SER SER A . n A 1 9 GLU 9 36 36 GLU GLU A . n A 1 10 MET 10 37 ? ? ? A . n A 1 11 SER 11 38 ? ? ? A . n A 1 12 ILE 12 39 ? ? ? A . n A 1 13 ASP 13 40 40 ASP ASP A . n A 1 14 GLY 14 41 41 GLY GLY A . n A 1 15 LEU 15 42 42 LEU LEU A . n A 1 16 CYS 16 43 43 CYS CYS A . n A 1 17 GLN 17 44 44 GLN GLN A . n A 1 18 CYS 18 45 45 CYS CYS A . n A 1 19 ALA 19 46 46 ALA ALA A . n A 1 20 PRO 20 47 47 PRO PRO A . n A 1 21 ILE 21 48 48 ILE ILE A . n A 1 22 MET 22 49 49 MET MET A . n A 1 23 SER 23 50 50 SER SER A . n A 1 24 GLU 24 51 51 GLU GLU A . n A 1 25 TYR 25 52 52 TYR TYR A . n A 1 26 GLU 26 53 53 GLU GLU A . n A 1 27 ILE 27 54 54 ILE ILE A . n A 1 28 ILE 28 55 55 ILE ILE A . n A 1 29 CYS 29 56 56 CYS CYS A . n A 1 30 PRO 30 57 57 PRO PRO A . n A 1 31 ALA 31 58 58 ALA ALA A . n A 1 32 ASN 32 59 59 ASN ASN A . n A 1 33 ALA 33 60 60 ALA ALA A . n A 1 34 GLU 34 61 61 GLU GLU A . n A 1 35 ASN 35 62 62 ASN ASN A . n A 1 36 PRO 36 63 63 PRO PRO A . n A 1 37 THR 37 64 64 THR THR A . n A 1 38 PHE 38 65 65 PHE PHE A . n A 1 39 ARG 39 66 66 ARG ARG A . n A 1 40 LEU 40 67 67 LEU LEU A . n A 1 41 THR 41 68 68 THR THR A . n A 1 42 ILE 42 69 69 ILE ILE A . n A 1 43 GLN 43 70 70 GLN GLN A . n A 1 44 PRO 44 71 71 PRO PRO A . n A 1 45 LYS 45 72 72 LYS LYS A . n A 1 46 ASP 46 73 73 ASP ASP A . n A 1 47 TYR 47 74 74 TYR TYR A . n A 1 48 VAL 48 75 75 VAL VAL A . n A 1 49 GLN 49 76 76 GLN GLN A . n A 1 50 ILE 50 77 77 ILE ILE A . n A 1 51 MET 51 78 78 MET MET A . n A 1 52 CYS 52 79 79 CYS CYS A . n A 1 53 ASN 53 80 80 ASN ASN A . n A 1 54 LEU 54 81 81 LEU LEU A . n A 1 55 THR 55 82 82 THR THR A . n A 1 56 ASP 56 83 83 ASP ASP A . n A 1 57 THR 57 84 84 THR THR A . n A 1 58 THR 58 85 85 THR THR A . n A 1 59 ASP 59 86 86 ASP ASP A . n A 1 60 TYR 60 87 87 TYR TYR A . n A 1 61 GLN 61 88 88 GLN GLN A . n A 1 62 GLN 62 89 89 GLN GLN A . n A 1 63 LEU 63 90 90 LEU LEU A . n A 1 64 PRO 64 91 91 PRO PRO A . n A 1 65 LYS 65 92 92 LYS LYS A . n A 1 66 LYS 66 93 93 LYS LYS A . n A 1 67 LEU 67 94 94 LEU LEU A . n A 1 68 ARG 68 95 95 ARG ARG A . n A 1 69 ILE 69 96 96 ILE ILE A . n A 1 70 GLY 70 97 97 GLY GLY A . n A 1 71 GLU 71 98 98 GLU GLU A . n A 1 72 VAL 72 99 99 VAL VAL A . n A 1 73 ASP 73 100 100 ASP ASP A . n A 1 74 ARG 74 101 101 ARG ARG A . n A 1 75 VAL 75 102 102 VAL VAL A . n A 1 76 GLN 76 103 103 GLN GLN A . n A 1 77 MET 77 104 104 MET MET A . n A 1 78 ARG 78 105 105 ARG ARG A . n A 1 79 ARG 79 106 106 ARG ARG A . n A 1 80 CYS 80 107 107 CYS CYS A . n A 1 81 MET 81 108 108 MET MET A . n A 1 82 LEU 82 109 109 LEU LEU A . n A 1 83 PRO 83 110 110 PRO PRO A . n A 1 84 GLY 84 111 111 GLY GLY A . n A 1 85 HIS 85 112 112 HIS HIS A . n A 1 86 THR 86 113 113 THR THR A . n A 1 87 PRO 87 114 114 PRO PRO A . n A 1 88 ILE 88 115 115 ILE ILE A . n A 1 89 ALA 89 116 116 ALA ALA A . n A 1 90 SER 90 117 117 SER SER A . n A 1 91 ILE 91 118 118 ILE ILE A . n A 1 92 LEU 92 119 119 LEU LEU A . n A 1 93 ASP 93 120 120 ASP ASP A . n A 1 94 TYR 94 121 121 TYR TYR A . n A 1 95 LEU 95 122 122 LEU LEU A . n A 1 96 GLY 96 123 123 GLY GLY A . n A 1 97 ILE 97 124 124 ILE ILE A . n A 1 98 VAL 98 125 125 VAL VAL A . n A 1 99 SER 99 126 126 SER SER A . n A 1 100 PRO 100 127 127 PRO PRO A . n A 1 101 THR 101 128 128 THR THR A . n A 1 102 THR 102 129 129 THR THR A . n A 1 103 LEU 103 130 130 LEU LEU A . n A 1 104 ILE 104 131 131 ILE ILE A . n A 1 105 PHE 105 132 132 PHE PHE A . n A 1 106 GLU 106 133 133 GLU GLU A . n A 1 107 SER 107 134 134 SER SER A . n A 1 108 ASP 108 135 135 ASP ASP A . n A 1 109 ASN 109 136 136 ASN ASN A . n A 1 110 LEU 110 137 137 LEU LEU A . n A 1 111 GLY 111 138 138 GLY GLY A . n A 1 112 MET 112 139 139 MET MET A . n A 1 113 ASN 113 140 140 ASN ASN A . n A 1 114 ILE 114 141 141 ILE ILE A . n A 1 115 THR 115 142 142 THR THR A . n A 1 116 ARG 116 143 143 ARG ARG A . n A 1 117 GLN 117 144 144 GLN GLN A . n A 1 118 HIS 118 145 145 HIS HIS A . n A 1 119 LEU 119 146 146 LEU LEU A . n A 1 120 ASP 120 147 147 ASP ASP A . n A 1 121 ARG 121 148 148 ARG ARG A . n A 1 122 LEU 122 149 149 LEU LEU A . n A 1 123 HIS 123 150 150 HIS HIS A . n A 1 124 GLY 124 151 151 GLY GLY A . n A 1 125 LEU 125 152 152 LEU LEU A . n A 1 126 LYS 126 153 153 LYS LYS A . n A 1 127 ARG 127 154 154 ARG ARG A . n A 1 128 PHE 128 155 155 PHE PHE A . n A 1 129 ARG 129 156 156 ARG ARG A . n A 1 130 PHE 130 157 157 PHE PHE A . n A 1 131 THR 131 158 158 THR THR A . n A 1 132 THR 132 159 159 THR THR A . n A 1 133 ARG 133 160 160 ARG ARG A . n A 1 134 ARG 134 161 161 ARG ARG A . n A 1 135 LEU 135 162 162 LEU LEU A . n A 1 136 THR 136 163 163 THR THR A . n A 1 137 HIS 137 164 164 HIS HIS A . n A 1 138 ILE 138 165 165 ILE ILE A . n A 1 139 PRO 139 166 166 PRO PRO A . n A 1 140 ALA 140 167 167 ALA ALA A . n A 1 141 ASN 141 168 168 ASN ASN A . n A 1 142 LEU 142 169 169 LEU LEU A . n A 1 143 LEU 143 170 170 LEU LEU A . n A 1 144 THR 144 171 171 THR THR A . n A 1 145 ASP 145 172 172 ASP ASP A . n A 1 146 MET 146 173 173 MET MET A . n A 1 147 ARG 147 174 174 ARG ARG A . n A 1 148 ASN 148 175 175 ASN ASN A . n A 1 149 LEU 149 176 176 LEU LEU A . n A 1 150 SER 150 177 177 SER SER A . n A 1 151 HIS 151 178 178 HIS HIS A . n A 1 152 LEU 152 179 179 LEU LEU A . n A 1 153 GLU 153 180 180 GLU GLU A . n A 1 154 LEU 154 181 181 LEU LEU A . n A 1 155 ARG 155 182 182 ARG ARG A . n A 1 156 ALA 156 183 183 ALA ALA A . n A 1 157 ASN 157 184 184 ASN ASN A . n A 1 158 ILE 158 185 185 ILE ILE A . n A 1 159 GLU 159 186 186 GLU GLU A . n A 1 160 GLU 160 187 187 GLU GLU A . n A 1 161 MET 161 188 188 MET MET A . n A 1 162 PRO 162 189 189 PRO PRO A . n A 1 163 SER 163 190 190 SER SER A . n A 1 164 HIS 164 191 191 HIS HIS A . n A 1 165 LEU 165 192 192 LEU LEU A . n A 1 166 PHE 166 193 193 PHE PHE A . n A 1 167 ASP 167 194 194 ASP ASP A . n A 1 168 ASP 168 195 195 ASP ASP A . n A 1 169 LEU 169 196 196 LEU LEU A . n A 1 170 GLU 170 197 197 GLU GLU A . n A 1 171 ASN 171 198 198 ASN ASN A . n A 1 172 LEU 172 199 199 LEU LEU A . n A 1 173 GLU 173 200 200 GLU GLU A . n A 1 174 SER 174 201 201 SER SER A . n A 1 175 ILE 175 202 202 ILE ILE A . n A 1 176 GLU 176 203 203 GLU GLU A . n A 1 177 PHE 177 204 204 PHE PHE A . n A 1 178 GLY 178 205 205 GLY GLY A . n A 1 179 SER 179 206 206 SER SER A . n A 1 180 ASN 180 207 207 ASN ASN A . n A 1 181 LYS 181 208 208 LYS LYS A . n A 1 182 LEU 182 209 209 LEU LEU A . n A 1 183 ARG 183 210 210 ARG ARG A . n A 1 184 GLN 184 211 211 GLN GLN A . n A 1 185 MET 185 212 212 MET MET A . n A 1 186 PRO 186 213 213 PRO PRO A . n A 1 187 ARG 187 214 214 ARG ARG A . n A 1 188 GLY 188 215 215 GLY GLY A . n A 1 189 ILE 189 216 216 ILE ILE A . n A 1 190 PHE 190 217 217 PHE PHE A . n A 1 191 GLY 191 218 218 GLY GLY A . n A 1 192 LYS 192 219 219 LYS LYS A . n A 1 193 MET 193 220 220 MET MET A . n A 1 194 PRO 194 221 221 PRO PRO A . n A 1 195 LYS 195 222 222 LYS LYS A . n A 1 196 LEU 196 223 223 LEU LEU A . n A 1 197 LYS 197 224 224 LYS LYS A . n A 1 198 GLN 198 225 225 GLN GLN A . n A 1 199 LEU 199 226 226 LEU LEU A . n A 1 200 ASN 200 227 227 ASN ASN A . n A 1 201 LEU 201 228 228 LEU LEU A . n A 1 202 TRP 202 229 229 TRP TRP A . n A 1 203 SER 203 230 230 SER SER A . n A 1 204 ASN 204 231 231 ASN ASN A . n A 1 205 GLN 205 232 232 GLN GLN A . n A 1 206 LEU 206 233 233 LEU LEU A . n A 1 207 HIS 207 234 234 HIS HIS A . n A 1 208 ASN 208 235 235 ASN ASN A . n A 1 209 LEU 209 236 236 LEU LEU A . n A 1 210 THR 210 237 237 THR THR A . n A 1 211 LYS 211 238 238 LYS LYS A . n A 1 212 HIS 212 239 239 HIS HIS A . n A 1 213 ASP 213 240 240 ASP ASP A . n A 1 214 PHE 214 241 241 PHE PHE A . n A 1 215 GLU 215 242 242 GLU GLU A . n A 1 216 GLY 216 243 243 GLY GLY A . n A 1 217 ALA 217 244 244 ALA ALA A . n A 1 218 THR 218 245 245 THR THR A . n A 1 219 SER 219 246 246 SER SER A . n A 1 220 VAL 220 247 247 VAL VAL A . n A 1 221 LEU 221 248 248 LEU LEU A . n A 1 222 GLY 222 249 249 GLY GLY A . n A 1 223 ILE 223 250 250 ILE ILE A . n A 1 224 ASP 224 251 251 ASP ASP A . n A 1 225 ILE 225 252 252 ILE ILE A . n A 1 226 HIS 226 253 253 HIS HIS A . n A 1 227 ASP 227 254 254 ASP ASP A . n A 1 228 ASN 228 255 255 ASN ASN A . n A 1 229 GLY 229 256 256 GLY GLY A . n A 1 230 ILE 230 257 257 ILE ILE A . n A 1 231 GLU 231 258 258 GLU GLU A . n A 1 232 GLN 232 259 259 GLN GLN A . n A 1 233 LEU 233 260 260 LEU LEU A . n A 1 234 PRO 234 261 261 PRO PRO A . n A 1 235 HIS 235 262 262 HIS HIS A . n A 1 236 ASP 236 263 263 ASP ASP A . n A 1 237 VAL 237 264 264 VAL VAL A . n A 1 238 PHE 238 265 265 PHE PHE A . n A 1 239 ALA 239 266 266 ALA ALA A . n A 1 240 HIS 240 267 267 HIS HIS A . n A 1 241 LEU 241 268 268 LEU LEU A . n A 1 242 THR 242 269 269 THR THR A . n A 1 243 ASN 243 270 270 ASN ASN A . n A 1 244 VAL 244 271 271 VAL VAL A . n A 1 245 THR 245 272 272 THR THR A . n A 1 246 ASP 246 273 273 ASP ASP A . n A 1 247 ILE 247 274 274 ILE ILE A . n A 1 248 ASN 248 275 275 ASN ASN A . n A 1 249 LEU 249 276 276 LEU LEU A . n A 1 250 SER 250 277 277 SER SER A . n A 1 251 ALA 251 278 278 ALA ALA A . n A 1 252 ASN 252 279 279 ASN ASN A . n A 1 253 LEU 253 280 280 LEU LEU A . n A 1 254 PHE 254 281 281 PHE PHE A . n A 1 255 ARG 255 282 282 ARG ARG A . n A 1 256 SER 256 283 283 SER SER A . n A 1 257 LEU 257 284 284 LEU LEU A . n A 1 258 PRO 258 285 285 PRO PRO A . n A 1 259 GLN 259 286 286 GLN GLN A . n A 1 260 GLY 260 287 287 GLY GLY A . n A 1 261 LEU 261 288 288 LEU LEU A . n A 1 262 PHE 262 289 289 PHE PHE A . n A 1 263 ASP 263 290 290 ASP ASP A . n A 1 264 HIS 264 291 291 HIS HIS A . n A 1 265 ASN 265 292 292 ASN ASN A . n A 1 266 LYS 266 293 293 LYS LYS A . n A 1 267 HIS 267 294 294 HIS HIS A . n A 1 268 LEU 268 295 295 LEU LEU A . n A 1 269 ASN 269 296 296 ASN ASN A . n A 1 270 GLU 270 297 297 GLU GLU A . n A 1 271 VAL 271 298 298 VAL VAL A . n A 1 272 ARG 272 299 299 ARG ARG A . n A 1 273 LEU 273 300 300 LEU LEU A . n A 1 274 MET 274 301 301 MET MET A . n A 1 275 ASN 275 302 302 ASN ASN A . n A 1 276 ASN 276 303 303 ASN ASN A . n A 1 277 ARG 277 304 304 ARG ARG A . n A 1 278 VAL 278 305 305 VAL VAL A . n A 1 279 PRO 279 306 306 PRO PRO A . n A 1 280 LEU 280 307 307 LEU LEU A . n A 1 281 ALA 281 308 308 ALA ALA A . n A 1 282 THR 282 309 309 THR THR A . n A 1 283 LEU 283 310 310 LEU LEU A . n A 1 284 PRO 284 311 311 PRO PRO A . n A 1 285 SER 285 312 312 SER SER A . n A 1 286 ARG 286 313 313 ARG ARG A . n A 1 287 LEU 287 314 314 LEU LEU A . n A 1 288 PHE 288 315 315 PHE PHE A . n A 1 289 ALA 289 316 316 ALA ALA A . n A 1 290 ASN 290 317 317 ASN ASN A . n A 1 291 GLN 291 318 318 GLN GLN A . n A 1 292 PRO 292 319 319 PRO PRO A . n A 1 293 GLU 293 320 320 GLU GLU A . n A 1 294 LEU 294 321 321 LEU LEU A . n A 1 295 GLN 295 322 322 GLN GLN A . n A 1 296 ILE 296 323 323 ILE ILE A . n A 1 297 LEU 297 324 324 LEU LEU A . n A 1 298 ARG 298 325 325 ARG ARG A . n A 1 299 LEU 299 326 326 LEU LEU A . n A 1 300 ARG 300 327 327 ARG ARG A . n A 1 301 ALA 301 328 328 ALA ALA A . n A 1 302 GLU 302 329 329 GLU GLU A . n A 1 303 LEU 303 330 330 LEU LEU A . n A 1 304 GLN 304 331 331 GLN GLN A . n A 1 305 SER 305 332 332 SER SER A . n A 1 306 LEU 306 333 333 LEU LEU A . n A 1 307 PRO 307 334 334 PRO PRO A . n A 1 308 GLY 308 335 335 GLY GLY A . n A 1 309 ASP 309 336 336 ASP ASP A . n A 1 310 LEU 310 337 337 LEU LEU A . n A 1 311 PHE 311 338 338 PHE PHE A . n A 1 312 GLU 312 339 339 GLU GLU A . n A 1 313 HIS 313 340 340 HIS HIS A . n A 1 314 SER 314 341 341 SER SER A . n A 1 315 THR 315 342 342 THR THR A . n A 1 316 GLN 316 343 343 GLN GLN A . n A 1 317 ILE 317 344 344 ILE ILE A . n A 1 318 THR 318 345 345 THR THR A . n A 1 319 ASN 319 346 346 ASN ASN A . n A 1 320 ILE 320 347 347 ILE ILE A . n A 1 321 SER 321 348 348 SER SER A . n A 1 322 LEU 322 349 349 LEU LEU A . n A 1 323 GLY 323 350 350 GLY GLY A . n A 1 324 ASP 324 351 351 ASP ASP A . n A 1 325 ASN 325 352 352 ASN ASN A . n A 1 326 LEU 326 353 353 LEU LEU A . n A 1 327 LEU 327 354 354 LEU LEU A . n A 1 328 LYS 328 355 355 LYS LYS A . n A 1 329 THR 329 356 356 THR THR A . n A 1 330 LEU 330 357 357 LEU LEU A . n A 1 331 PRO 331 358 358 PRO PRO A . n A 1 332 ALA 332 359 359 ALA ALA A . n A 1 333 THR 333 360 360 THR THR A . n A 1 334 LEU 334 361 361 LEU LEU A . n A 1 335 LEU 335 362 362 LEU LEU A . n A 1 336 GLU 336 363 363 GLU GLU A . n A 1 337 HIS 337 364 364 HIS HIS A . n A 1 338 GLN 338 365 365 GLN GLN A . n A 1 339 VAL 339 366 366 VAL VAL A . n A 1 340 ASN 340 367 367 ASN ASN A . n A 1 341 LEU 341 368 368 LEU LEU A . n A 1 342 LEU 342 369 369 LEU LEU A . n A 1 343 SER 343 370 370 SER SER A . n A 1 344 LEU 344 371 371 LEU LEU A . n A 1 345 ASP 345 372 372 ASP ASP A . n A 1 346 LEU 346 373 373 LEU LEU A . n A 1 347 SER 347 374 374 SER SER A . n A 1 348 ASN 348 375 375 ASN ASN A . n A 1 349 ASN 349 376 376 ASN ASN A . n A 1 350 ARG 350 377 377 ARG ARG A . n A 1 351 LEU 351 378 378 LEU LEU A . n A 1 352 THR 352 379 379 THR THR A . n A 1 353 HIS 353 380 380 HIS HIS A . n A 1 354 LEU 354 381 381 LEU LEU A . n A 1 355 PRO 355 382 382 PRO PRO A . n A 1 356 ASP 356 383 383 ASP ASP A . n A 1 357 SER 357 384 384 SER SER A . n A 1 358 LEU 358 385 385 LEU LEU A . n A 1 359 PHE 359 386 386 PHE PHE A . n A 1 360 ALA 360 387 387 ALA ALA A . n A 1 361 HIS 361 388 388 HIS HIS A . n A 1 362 THR 362 389 389 THR THR A . n A 1 363 THR 363 390 390 THR THR A . n A 1 364 ASN 364 391 391 ASN ASN A . n A 1 365 LEU 365 392 392 LEU LEU A . n A 1 366 THR 366 393 393 THR THR A . n A 1 367 ASP 367 394 394 ASP ASP A . n A 1 368 LEU 368 395 395 LEU LEU A . n A 1 369 ARG 369 396 396 ARG ARG A . n A 1 370 LEU 370 397 397 LEU LEU A . n A 1 371 GLU 371 398 398 GLU GLU A . n A 1 372 ASP 372 399 399 ASP ASP A . n A 1 373 ASN 373 400 400 ASN ASN A . n A 1 374 LEU 374 401 401 LEU LEU A . n A 1 375 LEU 375 402 402 LEU LEU A . n A 1 376 THR 376 403 403 THR THR A . n A 1 377 GLY 377 404 404 GLY GLY A . n A 1 378 ILE 378 405 405 ILE ILE A . n A 1 379 SER 379 406 406 SER SER A . n A 1 380 GLY 380 407 407 GLY GLY A . n A 1 381 ASP 381 408 408 ASP ASP A . n A 1 382 ILE 382 409 409 ILE ILE A . n A 1 383 PHE 383 410 410 PHE PHE A . n A 1 384 SER 384 411 411 SER SER A . n A 1 385 ASN 385 412 412 ASN ASN A . n A 1 386 LEU 386 413 413 LEU LEU A . n A 1 387 GLY 387 414 414 GLY GLY A . n A 1 388 ASN 388 415 415 ASN ASN A . n A 1 389 LEU 389 416 416 LEU LEU A . n A 1 390 VAL 390 417 417 VAL VAL A . n A 1 391 THR 391 418 418 THR THR A . n A 1 392 LEU 392 419 419 LEU LEU A . n A 1 393 VAL 393 420 420 VAL VAL A . n A 1 394 MET 394 421 421 MET MET A . n A 1 395 SER 395 422 422 SER SER A . n A 1 396 ARG 396 423 423 ARG ARG A . n A 1 397 ASN 397 424 424 ASN ASN A . n A 1 398 ARG 398 425 425 ARG ARG A . n A 1 399 LEU 399 426 426 LEU LEU A . n A 1 400 ARG 400 427 427 ARG ARG A . n A 1 401 THR 401 428 428 THR THR A . n A 1 402 ILE 402 429 429 ILE ILE A . n A 1 403 ASP 403 430 430 ASP ASP A . n A 1 404 SER 404 431 431 SER SER A . n A 1 405 ARG 405 432 432 ARG ARG A . n A 1 406 ALA 406 433 433 ALA ALA A . n A 1 407 PHE 407 434 434 PHE PHE A . n A 1 408 VAL 408 435 435 VAL VAL A . n A 1 409 SER 409 436 436 SER SER A . n A 1 410 THR 410 437 437 THR THR A . n A 1 411 ASN 411 438 438 ASN ASN A . n A 1 412 GLY 412 439 439 GLY GLY A . n A 1 413 LEU 413 440 440 LEU LEU A . n A 1 414 ARG 414 441 441 ARG ARG A . n A 1 415 HIS 415 442 442 HIS HIS A . n A 1 416 LEU 416 443 443 LEU LEU A . n A 1 417 HIS 417 444 444 HIS HIS A . n A 1 418 LEU 418 445 445 LEU LEU A . n A 1 419 ASP 419 446 446 ASP ASP A . n A 1 420 HIS 420 447 447 HIS HIS A . n A 1 421 ASN 421 448 448 ASN ASN A . n A 1 422 ASP 422 449 449 ASP ASP A . n A 1 423 ILE 423 450 450 ILE ILE A . n A 1 424 ASP 424 451 451 ASP ASP A . n A 1 425 LEU 425 452 452 LEU LEU A . n A 1 426 GLN 426 453 453 GLN GLN A . n A 1 427 GLN 427 454 454 GLN GLN A . n A 1 428 PRO 428 455 455 PRO PRO A . n A 1 429 LEU 429 456 456 LEU LEU A . n A 1 430 LEU 430 457 457 LEU LEU A . n A 1 431 ASP 431 458 458 ASP ASP A . n A 1 432 ILE 432 459 459 ILE ILE A . n A 1 433 MET 433 460 460 MET MET A . n A 1 434 LEU 434 461 461 LEU LEU A . n A 1 435 GLN 435 462 462 GLN GLN A . n A 1 436 THR 436 463 463 THR THR A . n A 1 437 GLN 437 464 464 GLN GLN A . n A 1 438 ILE 438 465 465 ILE ILE A . n A 1 439 ASN 439 466 466 ASN ASN A . n A 1 440 SER 440 467 467 SER SER A . n A 1 441 PRO 441 468 468 PRO PRO A . n A 1 442 PHE 442 469 469 PHE PHE A . n A 1 443 GLY 443 470 470 GLY GLY A . n A 1 444 TYR 444 471 471 TYR TYR A . n A 1 445 MET 445 472 472 MET MET A . n A 1 446 HIS 446 473 473 HIS HIS A . n A 1 447 GLY 447 474 474 GLY GLY A . n A 1 448 LEU 448 475 475 LEU LEU A . n A 1 449 LEU 449 476 476 LEU LEU A . n A 1 450 THR 450 477 477 THR THR A . n A 1 451 LEU 451 478 478 LEU LEU A . n A 1 452 ASN 452 479 479 ASN ASN A . n A 1 453 LEU 453 480 480 LEU LEU A . n A 1 454 ARG 454 481 481 ARG ARG A . n A 1 455 ASN 455 482 482 ASN ASN A . n A 1 456 ASN 456 483 483 ASN ASN A . n A 1 457 SER 457 484 484 SER SER A . n A 1 458 ILE 458 485 485 ILE ILE A . n A 1 459 ILE 459 486 486 ILE ILE A . n A 1 460 PHE 460 487 487 PHE PHE A . n A 1 461 VAL 461 488 488 VAL VAL A . n A 1 462 TYR 462 489 489 TYR TYR A . n A 1 463 ASN 463 490 490 ASN ASN A . n A 1 464 ASP 464 491 491 ASP ASP A . n A 1 465 TRP 465 492 492 TRP TRP A . n A 1 466 LYS 466 493 493 LYS LYS A . n A 1 467 ASN 467 494 494 ASN ASN A . n A 1 468 THR 468 495 495 THR THR A . n A 1 469 MET 469 496 496 MET MET A . n A 1 470 LEU 470 497 497 LEU LEU A . n A 1 471 GLN 471 498 498 GLN GLN A . n A 1 472 LEU 472 499 499 LEU LEU A . n A 1 473 ARG 473 500 500 ARG ARG A . n A 1 474 GLU 474 501 501 GLU GLU A . n A 1 475 LEU 475 502 502 LEU LEU A . n A 1 476 ASP 476 503 503 ASP ASP A . n A 1 477 LEU 477 504 504 LEU LEU A . n A 1 478 SER 478 505 505 SER SER A . n A 1 479 TYR 479 506 506 TYR TYR A . n A 1 480 ASN 480 507 507 ASN ASN A . n A 1 481 ASN 481 508 508 ASN ASN A . n A 1 482 ILE 482 509 509 ILE ILE A . n A 1 483 SER 483 510 510 SER SER A . n A 1 484 SER 484 511 511 SER SER A . n A 1 485 LEU 485 512 512 LEU LEU A . n A 1 486 GLY 486 513 513 GLY GLY A . n A 1 487 TYR 487 514 514 TYR TYR A . n A 1 488 GLU 488 515 515 GLU GLU A . n A 1 489 ASP 489 516 516 ASP ASP A . n A 1 490 LEU 490 517 517 LEU LEU A . n A 1 491 ALA 491 518 518 ALA ALA A . n A 1 492 PHE 492 519 519 PHE PHE A . n A 1 493 LEU 493 520 520 LEU LEU A . n A 1 494 SER 494 521 521 SER SER A . n A 1 495 GLN 495 522 522 GLN GLN A . n A 1 496 ASN 496 523 523 ASN ASN A . n A 1 497 ARG 497 524 524 ARG ARG A . n A 1 498 LEU 498 525 525 LEU LEU A . n A 1 499 HIS 499 526 526 HIS HIS A . n A 1 500 VAL 500 527 527 VAL VAL A . n A 1 501 ASN 501 528 528 ASN ASN A . n A 1 502 MET 502 529 529 MET MET A . n A 1 503 THR 503 530 530 THR THR A . n A 1 504 HIS 504 531 531 HIS HIS A . n A 1 505 ASN 505 532 532 ASN ASN A . n A 1 506 LYS 506 533 533 LYS LYS A . n A 1 507 ILE 507 534 534 ILE ILE A . n A 1 508 ARG 508 535 535 ARG ARG A . n A 1 509 ARG 509 536 536 ARG ARG A . n A 1 510 ILE 510 537 537 ILE ILE A . n A 1 511 ALA 511 538 538 ALA ALA A . n A 1 512 LEU 512 539 539 LEU LEU A . n A 1 513 PRO 513 540 540 PRO PRO A . n A 1 514 GLU 514 541 541 GLU GLU A . n A 1 515 ASP 515 542 542 ASP ASP A . n A 1 516 VAL 516 543 543 VAL VAL A . n A 1 517 HIS 517 544 ? ? ? A . n A 1 518 LEU 518 545 ? ? ? A . n A 1 519 GLY 519 546 ? ? ? A . n A 1 520 GLU 520 547 ? ? ? A . n A 1 521 GLY 521 548 ? ? ? A . n A 1 522 TYR 522 549 ? ? ? A . n A 1 523 ASN 523 550 ? ? ? A . n A 1 524 ASN 524 551 ? ? ? A . n A 1 525 ASN 525 552 ? ? ? A . n A 1 526 LEU 526 553 553 LEU LEU A . n A 1 527 VAL 527 554 554 VAL VAL A . n A 1 528 HIS 528 555 555 HIS HIS A . n A 1 529 VAL 529 556 556 VAL VAL A . n A 1 530 ASP 530 557 557 ASP ASP A . n A 1 531 LEU 531 558 558 LEU LEU A . n A 1 532 ASN 532 559 559 ASN ASN A . n A 1 533 ASP 533 560 560 ASP ASP A . n A 1 534 ASN 534 561 561 ASN ASN A . n A 1 535 PRO 535 562 562 PRO PRO A . n A 1 536 LEU 536 563 563 LEU LEU A . n A 1 537 VAL 537 564 564 VAL VAL A . n A 1 538 CYS 538 565 565 CYS CYS A . n A 1 539 ASP 539 566 566 ASP ASP A . n A 1 540 CYS 540 567 567 CYS CYS A . n A 1 541 THR 541 568 568 THR THR A . n A 1 542 ILE 542 569 569 ILE ILE A . n A 1 543 LEU 543 570 570 LEU LEU A . n A 1 544 TRP 544 571 571 TRP TRP A . n A 1 545 PHE 545 572 572 PHE PHE A . n A 1 546 ILE 546 573 573 ILE ILE A . n A 1 547 GLN 547 574 574 GLN GLN A . n A 1 548 LEU 548 575 575 LEU LEU A . n A 1 549 VAL 549 576 576 VAL VAL A . n A 1 550 ARG 550 577 577 ARG ARG A . n A 1 551 GLY 551 578 578 GLY GLY A . n A 1 552 VAL 552 579 579 VAL VAL A . n A 1 553 HIS 553 580 580 HIS HIS A . n A 1 554 LYS 554 581 581 LYS LYS A . n A 1 555 PRO 555 582 582 PRO PRO A . n A 1 556 GLN 556 583 583 GLN GLN A . n A 1 557 TYR 557 584 584 TYR TYR A . n A 1 558 SER 558 585 585 SER SER A . n A 1 559 ARG 559 586 586 ARG ARG A . n A 1 560 GLN 560 587 587 GLN GLN A . n A 1 561 PHE 561 588 588 PHE PHE A . n A 1 562 LYS 562 589 589 LYS LYS A . n A 1 563 LEU 563 590 590 LEU LEU A . n A 1 564 ARG 564 591 591 ARG ARG A . n A 1 565 THR 565 592 592 THR THR A . n A 1 566 ASP 566 593 593 ASP ASP A . n A 1 567 ARG 567 594 594 ARG ARG A . n A 1 568 LEU 568 595 595 LEU LEU A . n A 1 569 VAL 569 596 596 VAL VAL A . n A 1 570 CYS 570 597 597 CYS CYS A . n A 1 571 SER 571 598 598 SER SER A . n A 1 572 GLN 572 599 599 GLN GLN A . n A 1 573 PRO 573 600 600 PRO PRO A . n A 1 574 ASN 574 601 601 ASN ASN A . n A 1 575 VAL 575 602 602 VAL VAL A . n A 1 576 LEU 576 603 603 LEU LEU A . n A 1 577 GLU 577 604 604 GLU GLU A . n A 1 578 GLY 578 605 605 GLY GLY A . n A 1 579 THR 579 606 606 THR THR A . n A 1 580 PRO 580 607 607 PRO PRO A . n A 1 581 VAL 581 608 608 VAL VAL A . n A 1 582 ARG 582 609 609 ARG ARG A . n A 1 583 GLN 583 610 610 GLN GLN A . n A 1 584 ILE 584 611 611 ILE ILE A . n A 1 585 GLU 585 612 612 GLU GLU A . n A 1 586 PRO 586 613 613 PRO PRO A . n A 1 587 GLN 587 614 614 GLN GLN A . n A 1 588 THR 588 615 615 THR THR A . n A 1 589 LEU 589 616 616 LEU LEU A . n A 1 590 ILE 590 617 617 ILE ILE A . n A 1 591 CYS 591 618 618 CYS CYS A . n A 1 592 PRO 592 619 619 PRO PRO A . n A 1 593 LEU 593 620 620 LEU LEU A . n A 1 594 ASP 594 621 621 ASP ASP A . n A 1 595 PHE 595 622 ? ? ? A . n A 1 596 SER 596 623 ? ? ? A . n A 1 597 ASP 597 624 ? ? ? A . n A 1 598 ASP 598 625 ? ? ? A . n A 1 599 PRO 599 626 ? ? ? A . n A 1 600 ARG 600 627 ? ? ? A . n A 1 601 GLU 601 628 ? ? ? A . n A 1 602 ARG 602 629 ? ? ? A . n A 1 603 LYS 603 630 630 LYS LYS A . n A 1 604 CYS 604 631 631 CYS CYS A . n A 1 605 PRO 605 632 632 PRO PRO A . n A 1 606 ARG 606 633 633 ARG ARG A . n A 1 607 GLY 607 634 634 GLY GLY A . n A 1 608 CYS 608 635 635 CYS CYS A . n A 1 609 ASN 609 636 636 ASN ASN A . n A 1 610 CYS 610 637 637 CYS CYS A . n A 1 611 HIS 611 638 638 HIS HIS A . n A 1 612 VAL 612 639 639 VAL VAL A . n A 1 613 ARG 613 640 640 ARG ARG A . n A 1 614 THR 614 641 641 THR THR A . n A 1 615 TYR 615 642 642 TYR TYR A . n A 1 616 ASP 616 643 643 ASP ASP A . n A 1 617 LYS 617 644 644 LYS LYS A . n A 1 618 ALA 618 645 645 ALA ALA A . n A 1 619 LEU 619 646 646 LEU LEU A . n A 1 620 VAL 620 647 647 VAL VAL A . n A 1 621 ILE 621 648 648 ILE ILE A . n A 1 622 ASN 622 649 649 ASN ASN A . n A 1 623 CYS 623 650 650 CYS CYS A . n A 1 624 HIS 624 651 651 HIS HIS A . n A 1 625 SER 625 652 652 SER SER A . n A 1 626 GLY 626 653 653 GLY GLY A . n A 1 627 ASN 627 654 654 ASN ASN A . n A 1 628 LEU 628 655 655 LEU LEU A . n A 1 629 THR 629 656 656 THR THR A . n A 1 630 HIS 630 657 657 HIS HIS A . n A 1 631 VAL 631 658 658 VAL VAL A . n A 1 632 PRO 632 659 659 PRO PRO A . n A 1 633 ARG 633 660 660 ARG ARG A . n A 1 634 LEU 634 661 661 LEU LEU A . n A 1 635 PRO 635 662 662 PRO PRO A . n A 1 636 ASN 636 663 663 ASN ASN A . n A 1 637 LEU 637 664 664 LEU LEU A . n A 1 638 HIS 638 665 665 HIS HIS A . n A 1 639 LYS 639 666 666 LYS LYS A . n A 1 640 ASN 640 667 667 ASN ASN A . n A 1 641 MET 641 668 668 MET MET A . n A 1 642 GLN 642 669 669 GLN GLN A . n A 1 643 LEU 643 670 670 LEU LEU A . n A 1 644 MET 644 671 671 MET MET A . n A 1 645 GLU 645 672 672 GLU GLU A . n A 1 646 LEU 646 673 673 LEU LEU A . n A 1 647 HIS 647 674 674 HIS HIS A . n A 1 648 LEU 648 675 675 LEU LEU A . n A 1 649 GLU 649 676 676 GLU GLU A . n A 1 650 ASN 650 677 677 ASN ASN A . n A 1 651 ASN 651 678 678 ASN ASN A . n A 1 652 THR 652 679 679 THR THR A . n A 1 653 LEU 653 680 680 LEU LEU A . n A 1 654 LEU 654 681 681 LEU LEU A . n A 1 655 ARG 655 682 682 ARG ARG A . n A 1 656 LEU 656 683 683 LEU LEU A . n A 1 657 PRO 657 684 684 PRO PRO A . n A 1 658 SER 658 685 685 SER SER A . n A 1 659 ALA 659 686 686 ALA ALA A . n A 1 660 ASN 660 687 687 ASN ASN A . n A 1 661 THR 661 688 688 THR THR A . n A 1 662 PRO 662 689 689 PRO PRO A . n A 1 663 GLY 663 690 690 GLY GLY A . n A 1 664 TYR 664 691 691 TYR TYR A . n A 1 665 GLU 665 692 692 GLU GLU A . n A 1 666 SER 666 693 693 SER SER A . n A 1 667 VAL 667 694 694 VAL VAL A . n A 1 668 THR 668 695 695 THR THR A . n A 1 669 SER 669 696 696 SER SER A . n A 1 670 LEU 670 697 697 LEU LEU A . n A 1 671 HIS 671 698 698 HIS HIS A . n A 1 672 LEU 672 699 699 LEU LEU A . n A 1 673 ALA 673 700 700 ALA ALA A . n A 1 674 GLY 674 701 701 GLY GLY A . n A 1 675 ASN 675 702 702 ASN ASN A . n A 1 676 ASN 676 703 703 ASN ASN A . n A 1 677 LEU 677 704 704 LEU LEU A . n A 1 678 THR 678 705 705 THR THR A . n A 1 679 SER 679 706 706 SER SER A . n A 1 680 ILE 680 707 707 ILE ILE A . n A 1 681 ASP 681 708 708 ASP ASP A . n A 1 682 VAL 682 709 709 VAL VAL A . n A 1 683 ASP 683 710 710 ASP ASP A . n A 1 684 GLN 684 711 711 GLN GLN A . n A 1 685 LEU 685 712 712 LEU LEU A . n A 1 686 PRO 686 713 713 PRO PRO A . n A 1 687 THR 687 714 714 THR THR A . n A 1 688 ASN 688 715 715 ASN ASN A . n A 1 689 LEU 689 716 716 LEU LEU A . n A 1 690 THR 690 717 717 THR THR A . n A 1 691 HIS 691 718 718 HIS HIS A . n A 1 692 LEU 692 719 719 LEU LEU A . n A 1 693 ASP 693 720 720 ASP ASP A . n A 1 694 ILE 694 721 721 ILE ILE A . n A 1 695 SER 695 722 722 SER SER A . n A 1 696 TRP 696 723 723 TRP TRP A . n A 1 697 ASN 697 724 724 ASN ASN A . n A 1 698 HIS 698 725 725 HIS HIS A . n A 1 699 LEU 699 726 726 LEU LEU A . n A 1 700 GLN 700 727 727 GLN GLN A . n A 1 701 MET 701 728 728 MET MET A . n A 1 702 LEU 702 729 729 LEU LEU A . n A 1 703 ASN 703 730 730 ASN ASN A . n A 1 704 ALA 704 731 731 ALA ALA A . n A 1 705 THR 705 732 732 THR THR A . n A 1 706 VAL 706 733 733 VAL VAL A . n A 1 707 LEU 707 734 734 LEU LEU A . n A 1 708 GLY 708 735 735 GLY GLY A . n A 1 709 PHE 709 736 736 PHE PHE A . n A 1 710 LEU 710 737 737 LEU LEU A . n A 1 711 ASN 711 738 738 ASN ASN A . n A 1 712 ARG 712 739 ? ? ? A . n A 1 713 THR 713 740 ? ? ? A . n A 1 714 MET 714 741 ? ? ? A . n A 1 715 LYS 715 742 ? ? ? A . n A 1 716 TRP 716 743 743 TRP TRP A . n A 1 717 ARG 717 744 744 ARG ARG A . n A 1 718 SER 718 745 745 SER SER A . n A 1 719 VAL 719 746 746 VAL VAL A . n A 1 720 LYS 720 747 747 LYS LYS A . n A 1 721 LEU 721 748 748 LEU LEU A . n A 1 722 SER 722 749 749 SER SER A . n A 1 723 GLY 723 750 750 GLY GLY A . n A 1 724 ASN 724 751 751 ASN ASN A . n A 1 725 PRO 725 752 752 PRO PRO A . n A 1 726 TRP 726 753 753 TRP TRP A . n A 1 727 MET 727 754 754 MET MET A . n A 1 728 CYS 728 755 755 CYS CYS A . n A 1 729 ASP 729 756 756 ASP ASP A . n A 1 730 CYS 730 757 757 CYS CYS A . n A 1 731 THR 731 758 758 THR THR A . n A 1 732 ALA 732 759 759 ALA ALA A . n A 1 733 LYS 733 760 760 LYS LYS A . n A 1 734 PRO 734 761 761 PRO PRO A . n A 1 735 LEU 735 762 762 LEU LEU A . n A 1 736 LEU 736 763 763 LEU LEU A . n A 1 737 LEU 737 764 764 LEU LEU A . n A 1 738 PHE 738 765 765 PHE PHE A . n A 1 739 THR 739 766 766 THR THR A . n A 1 740 GLN 740 767 767 GLN GLN A . n A 1 741 ASP 741 768 768 ASP ASP A . n A 1 742 ASN 742 769 769 ASN ASN A . n A 1 743 PHE 743 770 770 PHE PHE A . n A 1 744 GLU 744 771 771 GLU GLU A . n A 1 745 ARG 745 772 772 ARG ARG A . n A 1 746 ILE 746 773 773 ILE ILE A . n A 1 747 GLY 747 774 774 GLY GLY A . n A 1 748 ASP 748 775 775 ASP ASP A . n A 1 749 ARG 749 776 776 ARG ARG A . n A 1 750 ASN 750 777 777 ASN ASN A . n A 1 751 GLU 751 778 778 GLU GLU A . n A 1 752 MET 752 779 779 MET MET A . n A 1 753 MET 753 780 780 MET MET A . n A 1 754 CYS 754 781 781 CYS CYS A . n A 1 755 VAL 755 782 782 VAL VAL A . n A 1 756 ASN 756 783 783 ASN ASN A . n A 1 757 ALA 757 784 784 ALA ALA A . n A 1 758 GLU 758 785 ? ? ? A . n A 1 759 MET 759 786 ? ? ? A . n A 1 760 PRO 760 787 787 PRO PRO A . n A 1 761 THR 761 788 788 THR THR A . n A 1 762 ARG 762 789 789 ARG ARG A . n A 1 763 MET 763 790 790 MET MET A . n A 1 764 VAL 764 791 791 VAL VAL A . n A 1 765 GLU 765 792 792 GLU GLU A . n A 1 766 LEU 766 793 793 LEU LEU A . n A 1 767 SER 767 794 794 SER SER A . n A 1 768 THR 768 795 795 THR THR A . n A 1 769 ASN 769 796 796 ASN ASN A . n A 1 770 ASP 770 797 797 ASP ASP A . n A 1 771 ILE 771 798 798 ILE ILE A . n A 1 772 CYS 772 799 799 CYS CYS A . n A 1 773 PRO 773 800 800 PRO PRO A . n A 1 774 ALA 774 801 ? ? ? A . n A 1 775 GLU 775 802 ? ? ? A . n A 1 776 THR 776 803 ? ? ? A . n A 1 777 GLY 777 804 ? ? ? A . n A 1 778 HIS 778 805 ? ? ? A . n A 1 779 HIS 779 806 ? ? ? A . n A 1 780 HIS 780 807 ? ? ? A . n A 1 781 HIS 781 808 ? ? ? A . n A 1 782 HIS 782 809 ? ? ? A . n A 1 783 HIS 783 810 ? ? ? A . n B 2 1 VAL 1 1 ? ? ? J . n B 2 2 GLY 2 2 ? ? ? J . n B 2 3 GLY 3 3 ? ? ? J . n B 2 4 SER 4 4 ? ? ? J . n B 2 5 ASP 5 5 5 ASP ASP J . n B 2 6 GLU 6 6 6 GLU GLU J . n B 2 7 ARG 7 7 7 ARG ARG J . n B 2 8 PHE 8 8 8 PHE PHE J . n B 2 9 LEU 9 9 9 LEU LEU J . n B 2 10 CYS 10 10 10 CYS CYS J . n B 2 11 ARG 11 11 11 ARG ARG J . n B 2 12 SER 12 12 12 SER SER J . n B 2 13 ILE 13 13 13 ILE ILE J . n B 2 14 ARG 14 14 14 ARG ARG J . n B 2 15 LYS 15 15 15 LYS LYS J . n B 2 16 LEU 16 16 16 LEU LEU J . n B 2 17 VAL 17 17 17 VAL VAL J . n B 2 18 TYR 18 18 18 TYR TYR J . n B 2 19 PRO 19 19 ? ? ? J . n B 2 20 LYS 20 20 ? ? ? J . n B 2 21 LYS 21 21 ? ? ? J . n B 2 22 GLY 22 22 ? ? ? J . n B 2 23 LEU 23 23 ? ? ? J . n B 2 24 ARG 24 24 ? ? ? J . n B 2 25 ALA 25 25 ? ? ? J . n B 2 26 ASP 26 26 ? ? ? J . n B 2 27 ASP 27 27 ? ? ? J . n B 2 28 THR 28 28 ? ? ? J . n B 2 29 TRP 29 29 ? ? ? J . n B 2 30 GLN 30 30 ? ? ? J . n B 2 31 LEU 31 31 ? ? ? J . n B 2 32 ILE 32 32 ? ? ? J . n B 2 33 VAL 33 33 ? ? ? J . n B 2 34 ASN 34 34 ? ? ? J . n B 2 35 ASN 35 35 ? ? ? J . n B 2 36 ASP 36 36 ? ? ? J . n B 2 37 GLU 37 37 ? ? ? J . n B 2 38 TYR 38 38 ? ? ? J . n B 2 39 LYS 39 39 ? ? ? J . n B 2 40 GLN 40 40 ? ? ? J . n B 2 41 ALA 41 41 ? ? ? J . n B 2 42 ILE 42 42 42 ILE ILE J . n B 2 43 GLN 43 43 43 GLN GLN J . n B 2 44 ILE 44 44 44 ILE ILE J . n B 2 45 GLU 45 45 45 GLU GLU J . n B 2 46 GLU 46 46 46 GLU GLU J . n B 2 47 CYS 47 47 47 CYS CYS J . n B 2 48 GLU 48 48 48 GLU GLU J . n B 2 49 GLY 49 49 49 GLY GLY J . n B 2 50 ALA 50 50 50 ALA ALA J . n B 2 51 ASP 51 51 51 ASP ASP J . n B 2 52 GLN 52 52 52 GLN GLN J . n B 2 53 PRO 53 53 53 PRO PRO J . n B 2 54 CYS 54 54 54 CYS CYS J . n B 2 55 ASP 55 55 55 ASP ASP J . n B 2 56 PHE 56 56 56 PHE PHE J . n B 2 57 ALA 57 57 57 ALA ALA J . n B 2 58 ALA 58 58 58 ALA ALA J . n B 2 59 ASN 59 59 59 ASN ASN J . n B 2 60 PHE 60 60 60 PHE PHE J . n B 2 61 PRO 61 61 61 PRO PRO J . n B 2 62 GLN 62 62 62 GLN GLN J . n B 2 63 SER 63 63 63 SER SER J . n B 2 64 TYR 64 64 64 TYR TYR J . n B 2 65 ASN 65 65 65 ASN ASN J . n B 2 66 PRO 66 66 66 PRO PRO J . n B 2 67 ILE 67 67 67 ILE ILE J . n B 2 68 CYS 68 68 68 CYS CYS J . n B 2 69 LYS 69 69 69 LYS LYS J . n B 2 70 GLN 70 70 70 GLN GLN J . n B 2 71 HIS 71 71 71 HIS HIS J . n B 2 72 TYR 72 72 72 TYR TYR J . n B 2 73 THR 73 73 73 THR THR J . n B 2 74 GLN 74 74 74 GLN GLN J . n B 2 75 GLN 75 75 ? ? ? J . n B 2 76 THR 76 76 ? ? ? J . n B 2 77 LEU 77 77 ? ? ? J . n B 2 78 ALA 78 78 ? ? ? J . n B 2 79 SER 79 79 ? ? ? J . n B 2 80 ILE 80 80 ? ? ? J . n B 2 81 LYS 81 81 ? ? ? J . n B 2 82 SER 82 82 ? ? ? J . n B 2 83 ASP 83 83 ? ? ? J . n B 2 84 GLY 84 84 ? ? ? J . n B 2 85 GLU 85 85 ? ? ? J . n B 2 86 LEU 86 86 ? ? ? J . n B 2 87 ASP 87 87 ? ? ? J . n B 2 88 VAL 88 88 ? ? ? J . n B 2 89 VAL 89 89 ? ? ? J . n B 2 90 GLN 90 90 ? ? ? J . n B 2 91 ASN 91 91 ? ? ? J . n B 2 92 SER 92 92 ? ? ? J . n B 2 93 PHE 93 93 ? ? ? J . n B 2 94 LYS 94 94 94 LYS LYS J . n B 2 95 ILE 95 95 95 ILE ILE J . n B 2 96 PRO 96 96 96 PRO PRO J . n B 2 97 SER 97 97 97 SER SER J . n B 2 98 CYS 98 98 98 CYS CYS J . n B 2 99 CYS 99 99 99 CYS CYS J . n B 2 100 LYS 100 100 100 LYS LYS J . n B 2 101 CYS 101 101 101 CYS CYS J . n B 2 102 ALA 102 102 102 ALA ALA J . n B 2 103 LEU 103 103 103 LEU LEU J . n B 2 104 LYS 104 104 104 LYS LYS J . n B 2 105 THR 105 105 105 THR THR J . n B 2 106 GLY 106 106 106 GLY GLY J . n B 2 107 LEU 107 107 107 LEU LEU J . n B 2 108 GLU 108 108 108 GLU GLU J . n B 2 109 HIS 109 109 109 HIS HIS J . n B 2 110 HIS 110 110 ? ? ? J . n B 2 111 HIS 111 111 ? ? ? J . n B 2 112 HIS 112 112 ? ? ? J . n B 2 113 HIS 113 113 ? ? ? J . n B 2 114 HIS 114 114 ? ? ? J . n C 2 1 VAL 1 1 1 VAL VAL K . n C 2 2 GLY 2 2 2 GLY GLY K . n C 2 3 GLY 3 3 3 GLY GLY K . n C 2 4 SER 4 4 4 SER SER K . n C 2 5 ASP 5 5 5 ASP ASP K . n C 2 6 GLU 6 6 6 GLU GLU K . n C 2 7 ARG 7 7 7 ARG ARG K . n C 2 8 PHE 8 8 8 PHE PHE K . n C 2 9 LEU 9 9 9 LEU LEU K . n C 2 10 CYS 10 10 10 CYS CYS K . n C 2 11 ARG 11 11 11 ARG ARG K . n C 2 12 SER 12 12 12 SER SER K . n C 2 13 ILE 13 13 13 ILE ILE K . n C 2 14 ARG 14 14 14 ARG ARG K . n C 2 15 LYS 15 15 15 LYS LYS K . n C 2 16 LEU 16 16 16 LEU LEU K . n C 2 17 VAL 17 17 ? ? ? K . n C 2 18 TYR 18 18 ? ? ? K . n C 2 19 PRO 19 19 ? ? ? K . n C 2 20 LYS 20 20 ? ? ? K . n C 2 21 LYS 21 21 ? ? ? K . n C 2 22 GLY 22 22 ? ? ? K . n C 2 23 LEU 23 23 ? ? ? K . n C 2 24 ARG 24 24 ? ? ? K . n C 2 25 ALA 25 25 ? ? ? K . n C 2 26 ASP 26 26 ? ? ? K . n C 2 27 ASP 27 27 ? ? ? K . n C 2 28 THR 28 28 ? ? ? K . n C 2 29 TRP 29 29 ? ? ? K . n C 2 30 GLN 30 30 ? ? ? K . n C 2 31 LEU 31 31 ? ? ? K . n C 2 32 ILE 32 32 ? ? ? K . n C 2 33 VAL 33 33 ? ? ? K . n C 2 34 ASN 34 34 ? ? ? K . n C 2 35 ASN 35 35 ? ? ? K . n C 2 36 ASP 36 36 ? ? ? K . n C 2 37 GLU 37 37 ? ? ? K . n C 2 38 TYR 38 38 ? ? ? K . n C 2 39 LYS 39 39 39 LYS LYS K . n C 2 40 GLN 40 40 40 GLN GLN K . n C 2 41 ALA 41 41 41 ALA ALA K . n C 2 42 ILE 42 42 42 ILE ILE K . n C 2 43 GLN 43 43 43 GLN GLN K . n C 2 44 ILE 44 44 44 ILE ILE K . n C 2 45 GLU 45 45 45 GLU GLU K . n C 2 46 GLU 46 46 46 GLU GLU K . n C 2 47 CYS 47 47 47 CYS CYS K . n C 2 48 GLU 48 48 48 GLU GLU K . n C 2 49 GLY 49 49 49 GLY GLY K . n C 2 50 ALA 50 50 50 ALA ALA K . n C 2 51 ASP 51 51 51 ASP ASP K . n C 2 52 GLN 52 52 52 GLN GLN K . n C 2 53 PRO 53 53 53 PRO PRO K . n C 2 54 CYS 54 54 54 CYS CYS K . n C 2 55 ASP 55 55 55 ASP ASP K . n C 2 56 PHE 56 56 56 PHE PHE K . n C 2 57 ALA 57 57 57 ALA ALA K . n C 2 58 ALA 58 58 58 ALA ALA K . n C 2 59 ASN 59 59 59 ASN ASN K . n C 2 60 PHE 60 60 60 PHE PHE K . n C 2 61 PRO 61 61 61 PRO PRO K . n C 2 62 GLN 62 62 62 GLN GLN K . n C 2 63 SER 63 63 63 SER SER K . n C 2 64 TYR 64 64 64 TYR TYR K . n C 2 65 ASN 65 65 65 ASN ASN K . n C 2 66 PRO 66 66 66 PRO PRO K . n C 2 67 ILE 67 67 67 ILE ILE K . n C 2 68 CYS 68 68 68 CYS CYS K . n C 2 69 LYS 69 69 69 LYS LYS K . n C 2 70 GLN 70 70 70 GLN GLN K . n C 2 71 HIS 71 71 71 HIS HIS K . n C 2 72 TYR 72 72 72 TYR TYR K . n C 2 73 THR 73 73 73 THR THR K . n C 2 74 GLN 74 74 ? ? ? K . n C 2 75 GLN 75 75 ? ? ? K . n C 2 76 THR 76 76 ? ? ? K . n C 2 77 LEU 77 77 ? ? ? K . n C 2 78 ALA 78 78 ? ? ? K . n C 2 79 SER 79 79 ? ? ? K . n C 2 80 ILE 80 80 ? ? ? K . n C 2 81 LYS 81 81 ? ? ? K . n C 2 82 SER 82 82 ? ? ? K . n C 2 83 ASP 83 83 ? ? ? K . n C 2 84 GLY 84 84 ? ? ? K . n C 2 85 GLU 85 85 ? ? ? K . n C 2 86 LEU 86 86 ? ? ? K . n C 2 87 ASP 87 87 ? ? ? K . n C 2 88 VAL 88 88 ? ? ? K . n C 2 89 VAL 89 89 ? ? ? K . n C 2 90 GLN 90 90 ? ? ? K . n C 2 91 ASN 91 91 ? ? ? K . n C 2 92 SER 92 92 ? ? ? K . n C 2 93 PHE 93 93 ? ? ? K . n C 2 94 LYS 94 94 94 LYS LYS K . n C 2 95 ILE 95 95 95 ILE ILE K . n C 2 96 PRO 96 96 96 PRO PRO K . n C 2 97 SER 97 97 97 SER SER K . n C 2 98 CYS 98 98 98 CYS CYS K . n C 2 99 CYS 99 99 99 CYS CYS K . n C 2 100 LYS 100 100 100 LYS LYS K . n C 2 101 CYS 101 101 101 CYS CYS K . n C 2 102 ALA 102 102 102 ALA ALA K . n C 2 103 LEU 103 103 103 LEU LEU K . n C 2 104 LYS 104 104 104 LYS LYS K . n C 2 105 THR 105 105 105 THR THR K . n C 2 106 GLY 106 106 106 GLY GLY K . n C 2 107 LEU 107 107 107 LEU LEU K . n C 2 108 GLU 108 108 ? ? ? K . n C 2 109 HIS 109 109 ? ? ? K . n C 2 110 HIS 110 110 ? ? ? K . n C 2 111 HIS 111 111 ? ? ? K . n C 2 112 HIS 112 112 ? ? ? K . n C 2 113 HIS 113 113 ? ? ? K . n C 2 114 HIS 114 114 ? ? ? K . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code D 3 NAG 1 2001 2001 NAG NAG A . E 3 NAG 2 2002 2002 NAG NAG A . F 4 BMA 3 2003 2003 BMA BMA A . G 4 BMA 4 2004 2004 BMA BMA A . H 5 MAN 5 2005 2005 MAN MAN A . I 3 NAG 1 2006 2501 NAG NAG A . J 3 NAG 1 2007 3001 NAG NAG A . K 3 NAG 1 2008 3501 NAG NAG A . L 3 NAG 2 2009 3502 NAG NAG A . M 3 NAG 1 2010 4001 NAG NAG A . N 3 NAG 2 2011 4002 NAG NAG A . O 4 BMA 3 2012 4003 BMA BMA A . P 3 NAG 1 2013 4501 NAG NAG A . Q 3 NAG 2 2014 4502 NAG NAG A . R 3 NAG 1 2015 5001 NAG NAG A . S 3 NAG 2 2016 5002 NAG NAG A . T 3 NAG 1 2017 6001 NAG NAG A . U 3 NAG 2 2018 6002 NAG NAG A . V 3 NAG 1 2019 6501 NAG NAG A . W 3 NAG 2 2020 6502 NAG NAG A . X 3 NAG 1 2021 7001 NAG NAG A . Y 3 NAG 1 2022 7501 NAG NAG A . Z 3 NAG 1 2023 8001 NAG NAG A . AA 6 EPE 1 2024 1 EPE EPE A . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 364 A ASN 391 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 676 A ASN 703 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 53 A ASN 80 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 148 A ASN 175 ? ASN 'GLYCOSYLATION SITE' 5 A ASN 501 A ASN 528 ? ASN 'GLYCOSYLATION SITE' 6 A ASN 243 A ASN 270 ? ASN 'GLYCOSYLATION SITE' 7 A ASN 208 A ASN 235 ? ASN 'GLYCOSYLATION SITE' 8 A ASN 113 A ASN 140 ? ASN 'GLYCOSYLATION SITE' 9 A ASN 319 A ASN 346 ? ASN 'GLYCOSYLATION SITE' 10 A ASN 455 A ASN 482 ? ASN 'GLYCOSYLATION SITE' 11 A ASN 627 A ASN 654 ? ASN 'GLYCOSYLATION SITE' 12 A ASN 481 A ASN 508 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details trimeric _pdbx_struct_assembly.oligomeric_count 3 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 12390 ? 1 MORE 61 ? 1 'SSA (A^2)' 41520 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2014-04-09 2 'Structure model' 1 1 2014-05-21 3 'Structure model' 1 2 2017-11-15 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # _pdbx_audit_revision_item.ordinal 1 _pdbx_audit_revision_item.revision_ordinal 3 _pdbx_audit_revision_item.data_content_type 'Structure model' _pdbx_audit_revision_item.item '_software.name' # _diffrn_reflns.diffrn_id 1 _diffrn_reflns.pdbx_d_res_high 3.910 _diffrn_reflns.pdbx_d_res_low ? _diffrn_reflns.pdbx_number_obs 22848 _diffrn_reflns.pdbx_Rmerge_I_obs 0.150 _diffrn_reflns.pdbx_Rsym_value ? _diffrn_reflns.pdbx_chi_squared ? _diffrn_reflns.av_sigmaI_over_netI ? _diffrn_reflns.pdbx_redundancy ? _diffrn_reflns.pdbx_percent_possible_obs 93.80 _diffrn_reflns.number 43793 _diffrn_reflns.pdbx_observed_criterion ? _diffrn_reflns.limit_h_max ? _diffrn_reflns.limit_h_min ? _diffrn_reflns.limit_k_max ? _diffrn_reflns.limit_k_min ? _diffrn_reflns.limit_l_max ? _diffrn_reflns.limit_l_min ? # loop_ _pdbx_phasing_MAD_set.id _pdbx_phasing_MAD_set.d_res_low _pdbx_phasing_MAD_set.d_res_high _pdbx_phasing_MAD_set.reflns_acentric _pdbx_phasing_MAD_set.reflns_centric _pdbx_phasing_MAD_set.power_acentric _pdbx_phasing_MAD_set.power_centric ISO_1 46.15 3.04 11103 774 0.000 0.000 ISO_2 46.15 3.04 11082 750 0.667 0.680 ISO_3 46.15 3.04 11065 748 1.245 1.236 ISO_4 46.15 3.04 11047 744 1.582 1.486 ANO_1 46.15 3.04 10474 0 1.046 0.000 ANO_2 46.15 3.04 15147 0 0.926 0.000 ANO_3 46.15 3.04 19988 0 0.687 0.000 ANO_4 46.15 3.04 23777 0 0.345 0.000 # loop_ _pdbx_phasing_MAD_set_shell.id _pdbx_phasing_MAD_set_shell.d_res_low _pdbx_phasing_MAD_set_shell.d_res_high _pdbx_phasing_MAD_set_shell.reflns_acentric _pdbx_phasing_MAD_set_shell.reflns_centric _pdbx_phasing_MAD_set_shell.power_acentric _pdbx_phasing_MAD_set_shell.power_centric ISO_1 46.15 13.07 219 41 0.000 0.000 ISO_1 13.07 9.43 490 61 0.000 0.000 ISO_1 9.43 7.75 641 65 0.000 0.000 ISO_1 7.75 6.74 757 65 0.000 0.000 ISO_1 6.74 6.04 876 67 0.000 0.000 ISO_1 6.04 5.52 974 66 0.000 0.000 ISO_1 5.52 5.12 1063 67 0.000 0.000 ISO_1 5.12 4.79 1103 73 0.000 0.000 ISO_1 4.79 4.52 1194 70 0.000 0.000 ISO_1 4.52 4.29 1246 73 0.000 0.000 ISO_1 4.29 4.09 1332 69 0.000 0.000 ISO_1 4.09 3.92 1206 57 0.000 0.000 ISO_1 3.92 3.77 2 0 0.000 0.000 ISO_1 3.77 3.63 0 0 0.000 0.000 ISO_1 3.63 3.51 0 0 0.000 0.000 ISO_1 3.51 3.40 0 0 0.000 0.000 ISO_1 3.40 3.30 0 0 0.000 0.000 ISO_1 3.30 3.20 0 0 0.000 0.000 ISO_1 3.20 3.12 0 0 0.000 0.000 ISO_1 3.12 3.04 0 0 0.000 0.000 ANO_1 46.15 13.07 195 0 3.061 0.000 ANO_1 13.07 9.43 444 0 3.268 0.000 ANO_1 9.43 7.75 593 0 2.712 0.000 ANO_1 7.75 6.74 713 0 1.923 0.000 ANO_1 6.74 6.04 826 0 1.398 0.000 ANO_1 6.04 5.52 918 0 1.124 0.000 ANO_1 5.52 5.12 1008 0 0.903 0.000 ANO_1 5.12 4.79 1048 0 0.741 0.000 ANO_1 4.79 4.52 1138 0 0.607 0.000 ANO_1 4.52 4.29 1192 0 0.485 0.000 ANO_1 4.29 4.09 1267 0 0.389 0.000 ANO_1 4.09 3.92 1132 0 0.285 0.000 ANO_1 3.92 3.77 0 0 0.000 0.000 ANO_1 3.77 3.63 0 0 0.000 0.000 ANO_1 3.63 3.51 0 0 0.000 0.000 ANO_1 3.51 3.40 0 0 0.000 0.000 ANO_1 3.40 3.30 0 0 0.000 0.000 ANO_1 3.30 3.20 0 0 0.000 0.000 ANO_1 3.20 3.12 0 0 0.000 0.000 ANO_1 3.12 3.04 0 0 0.000 0.000 ISO_2 46.15 13.07 214 36 1.546 1.329 ISO_2 13.07 9.43 487 58 1.638 1.171 ISO_2 9.43 7.75 640 61 1.540 1.120 ISO_2 7.75 6.74 757 64 1.246 0.883 ISO_2 6.74 6.04 876 65 0.998 0.761 ISO_2 6.04 5.52 974 62 0.791 0.573 ISO_2 5.52 5.12 1061 66 0.673 0.517 ISO_2 5.12 4.79 1102 73 0.562 0.407 ISO_2 4.79 4.52 1192 70 0.431 0.373 ISO_2 4.52 4.29 1244 72 0.342 0.288 ISO_2 4.29 4.09 1332 68 0.259 0.201 ISO_2 4.09 3.92 1202 55 0.205 0.191 ISO_2 3.92 3.77 1 0 0.158 0.000 ISO_2 3.77 3.63 0 0 0.000 0.000 ISO_2 3.63 3.51 0 0 0.000 0.000 ISO_2 3.51 3.40 0 0 0.000 0.000 ISO_2 3.40 3.30 0 0 0.000 0.000 ISO_2 3.30 3.20 0 0 0.000 0.000 ISO_2 3.20 3.12 0 0 0.000 0.000 ISO_2 3.12 3.04 0 0 0.000 0.000 ANO_2 46.15 13.07 196 0 4.022 0.000 ANO_2 13.07 9.43 465 0 4.363 0.000 ANO_2 9.43 7.75 622 0 3.576 0.000 ANO_2 7.75 6.74 733 0 2.618 0.000 ANO_2 6.74 6.04 853 0 1.940 0.000 ANO_2 6.04 5.52 946 0 1.469 0.000 ANO_2 5.52 5.12 1028 0 1.123 0.000 ANO_2 5.12 4.79 1089 0 0.927 0.000 ANO_2 4.79 4.52 1170 0 0.744 0.000 ANO_2 4.52 4.29 1230 0 0.545 0.000 ANO_2 4.29 4.09 1292 0 0.414 0.000 ANO_2 4.09 3.92 1341 0 0.305 0.000 ANO_2 3.92 3.77 1441 0 0.222 0.000 ANO_2 3.77 3.63 1510 0 0.172 0.000 ANO_2 3.63 3.51 1231 0 0.150 0.000 ANO_2 3.51 3.40 0 0 0.000 0.000 ANO_2 3.40 3.30 0 0 0.000 0.000 ANO_2 3.30 3.20 0 0 0.000 0.000 ANO_2 3.20 3.12 0 0 0.000 0.000 ANO_2 3.12 3.04 0 0 0.000 0.000 ISO_3 46.15 13.07 215 37 2.569 2.158 ISO_3 13.07 9.43 483 60 2.256 1.806 ISO_3 9.43 7.75 638 62 2.473 1.891 ISO_3 7.75 6.74 756 61 2.194 1.581 ISO_3 6.74 6.04 874 66 1.855 1.388 ISO_3 6.04 5.52 973 63 1.515 1.040 ISO_3 5.52 5.12 1063 66 1.179 0.804 ISO_3 5.12 4.79 1100 70 0.918 0.669 ISO_3 4.79 4.52 1191 69 0.734 0.591 ISO_3 4.52 4.29 1243 71 0.613 0.538 ISO_3 4.29 4.09 1327 67 0.513 0.386 ISO_3 4.09 3.92 1201 56 0.412 0.324 ISO_3 3.92 3.77 1 0 0.328 0.000 ISO_3 3.77 3.63 0 0 0.000 0.000 ISO_3 3.63 3.51 0 0 0.000 0.000 ISO_3 3.51 3.40 0 0 0.000 0.000 ISO_3 3.40 3.30 0 0 0.000 0.000 ISO_3 3.30 3.20 0 0 0.000 0.000 ISO_3 3.20 3.12 0 0 0.000 0.000 ISO_3 3.12 3.04 0 0 0.000 0.000 ANO_3 46.15 13.07 204 0 2.723 0.000 ANO_3 13.07 9.43 457 0 2.823 0.000 ANO_3 9.43 7.75 614 0 2.936 0.000 ANO_3 7.75 6.74 728 0 2.282 0.000 ANO_3 6.74 6.04 840 0 1.721 0.000 ANO_3 6.04 5.52 948 0 1.315 0.000 ANO_3 5.52 5.12 1042 0 1.109 0.000 ANO_3 5.12 4.79 1088 0 0.875 0.000 ANO_3 4.79 4.52 1170 0 0.708 0.000 ANO_3 4.52 4.29 1222 0 0.531 0.000 ANO_3 4.29 4.09 1305 0 0.411 0.000 ANO_3 4.09 3.92 1333 0 0.313 0.000 ANO_3 3.92 3.77 1434 0 0.231 0.000 ANO_3 3.77 3.63 1508 0 0.177 0.000 ANO_3 3.63 3.51 1529 0 0.142 0.000 ANO_3 3.51 3.40 1562 0 0.103 0.000 ANO_3 3.40 3.30 1643 0 0.089 0.000 ANO_3 3.30 3.20 1361 0 0.075 0.000 ANO_3 3.20 3.12 0 0 0.000 0.000 ANO_3 3.12 3.04 0 0 0.000 0.000 ISO_4 46.15 13.07 213 39 3.118 2.606 ISO_4 13.07 9.43 485 60 2.654 1.860 ISO_4 9.43 7.75 638 63 2.485 1.973 ISO_4 7.75 6.74 754 62 2.253 1.612 ISO_4 6.74 6.04 873 64 1.933 1.517 ISO_4 6.04 5.52 969 64 1.562 1.112 ISO_4 5.52 5.12 1057 63 1.249 0.913 ISO_4 5.12 4.79 1098 71 0.925 0.655 ISO_4 4.79 4.52 1190 70 0.745 0.651 ISO_4 4.52 4.29 1242 72 0.654 0.613 ISO_4 4.29 4.09 1326 63 0.584 0.430 ISO_4 4.09 3.92 1200 53 0.481 0.364 ISO_4 3.92 3.77 2 0 0.480 0.000 ISO_4 3.77 3.63 0 0 0.000 0.000 ISO_4 3.63 3.51 0 0 0.000 0.000 ISO_4 3.51 3.40 0 0 0.000 0.000 ISO_4 3.40 3.30 0 0 0.000 0.000 ISO_4 3.30 3.20 0 0 0.000 0.000 ISO_4 3.20 3.12 0 0 0.000 0.000 ISO_4 3.12 3.04 0 0 0.000 0.000 ANO_4 46.15 13.07 188 0 1.656 0.000 ANO_4 13.07 9.43 456 0 2.028 0.000 ANO_4 9.43 7.75 607 0 2.037 0.000 ANO_4 7.75 6.74 724 0 1.558 0.000 ANO_4 6.74 6.04 828 0 1.167 0.000 ANO_4 6.04 5.52 910 0 0.933 0.000 ANO_4 5.52 5.12 1015 0 0.726 0.000 ANO_4 5.12 4.79 1056 0 0.585 0.000 ANO_4 4.79 4.52 1150 0 0.456 0.000 ANO_4 4.52 4.29 1196 0 0.339 0.000 ANO_4 4.29 4.09 1290 0 0.249 0.000 ANO_4 4.09 3.92 1324 0 0.199 0.000 ANO_4 3.92 3.77 1442 0 0.131 0.000 ANO_4 3.77 3.63 1506 0 0.105 0.000 ANO_4 3.63 3.51 1531 0 0.076 0.000 ANO_4 3.51 3.40 1587 0 0.060 0.000 ANO_4 3.40 3.30 1674 0 0.052 0.000 ANO_4 3.30 3.20 1759 0 0.041 0.000 ANO_4 3.20 3.12 1747 0 0.035 0.000 ANO_4 3.12 3.04 1787 0 0.029 0.000 # loop_ _pdbx_phasing_MAD_set_site.id _pdbx_phasing_MAD_set_site.atom_type_symbol _pdbx_phasing_MAD_set_site.Cartn_x _pdbx_phasing_MAD_set_site.Cartn_y _pdbx_phasing_MAD_set_site.Cartn_z _pdbx_phasing_MAD_set_site.occupancy _pdbx_phasing_MAD_set_site.b_iso 1 SM 150.908 29.240 18.435 1.08 111.54 2 SM 166.845 64.470 28.396 0.92 130.65 3 SM 193.379 82.116 9.079 1.08 134.61 4 SM 167.250 68.105 45.159 1.07 202.41 # loop_ _pdbx_phasing_MAD_shell.d_res_low _pdbx_phasing_MAD_shell.d_res_high _pdbx_phasing_MAD_shell.reflns_acentric _pdbx_phasing_MAD_shell.fom_acentric _pdbx_phasing_MAD_shell.reflns_centric _pdbx_phasing_MAD_shell.fom_centric 46.15 13.07 225 0.873 42 0.690 13.07 9.43 490 0.836 69 0.543 9.43 7.75 644 0.819 68 0.578 7.75 6.74 758 0.773 67 0.528 6.74 6.04 878 0.712 70 0.427 6.04 5.52 975 0.655 71 0.349 5.52 5.12 1065 0.579 68 0.266 5.12 4.79 1109 0.497 73 0.201 4.79 4.52 1203 0.440 71 0.167 4.52 4.29 1255 0.368 74 0.151 4.29 4.09 1334 0.302 70 0.098 4.09 3.92 1374 0.255 74 0.103 3.92 3.77 1485 0.176 75 0.067 3.77 3.63 1556 0.141 73 0.070 3.63 3.51 1583 0.099 77 0.046 3.51 3.40 1620 0.064 71 0.032 3.40 3.30 1708 0.052 72 0.031 3.30 3.20 1787 0.034 71 0.029 3.20 3.12 1779 0.015 75 0.006 3.12 3.04 1819 0.013 75 0.005 # _phasing.method MAD # _phasing_MAD.entry_id 4LXS _phasing_MAD.pdbx_d_res_low 46.150 _phasing_MAD.pdbx_d_res_high 3.040 _phasing_MAD.pdbx_reflns_acentric 24647 _phasing_MAD.pdbx_fom_acentric 0.277 _phasing_MAD.pdbx_reflns_centric 1406 _phasing_MAD.pdbx_fom_centric 0.204 # loop_ _software.pdbx_ordinal _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id 1 XSCALE . ? package 'Wolfgang Kabsch' ? 'data scaling' http://www.mpimf-heidelberg.mpg.de/~kabsch/xds/html_doc/xscale_program.html ? ? 2 SHARP . ? package 'Eric de La Fortelle' sharp-develop@globalphasing.com phasing http://www.globalphasing.com/sharp/ ? ? 3 SOLOMON . ? program 'Jan P. Abrahams' ccp4@ccp4.ac.uk phasing http://www.ccp4.ac.uk/dist/html/solomon.html Fortran_77 ? 4 PHENIX 1.8.2_1309 ? package 'Paul D. Adams' PDAdams@lbl.gov refinement http://www.phenix-online.org/ C++ ? 5 PDB_EXTRACT 3.11 'April 22, 2011' package PDB deposit@deposit.rcsb.org 'data extraction' http://sw-tools.pdb.org/apps/PDB_EXTRACT/ C++ ? 6 MAR345 . ? ? ? ? 'data collection' ? ? ? 7 XDS . ? ? ? ? 'data reduction' ? ? ? # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 ND2 A ASN 270 ? ? C2 A NAG 2015 ? ? 1.92 2 1 OG A SER 467 ? ? OD2 A ASP 491 ? ? 2.09 3 1 SG J CYS 10 ? ? CB J CYS 68 ? ? 2.13 4 1 OG A SER 230 ? ? OD2 A ASP 254 ? ? 2.15 5 1 NH2 A ARG 640 ? ? OD2 A ASP 643 ? ? 2.17 6 1 OG A SER 696 ? ? NE2 A HIS 698 ? ? 2.19 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 LEU A 42 ? ? -103.66 -85.59 2 1 MET A 49 ? ? 49.61 -101.64 3 1 GLU A 51 ? ? -107.16 -164.00 4 1 LYS A 72 ? ? 65.48 -30.32 5 1 ASP A 73 ? ? -90.32 -91.77 6 1 VAL A 75 ? ? -161.25 118.43 7 1 ASN A 80 ? ? -153.13 80.76 8 1 THR A 82 ? ? -100.78 -67.51 9 1 ARG A 95 ? ? 58.86 71.59 10 1 SER A 126 ? ? 40.68 73.88 11 1 MET A 139 ? ? -157.87 -154.72 12 1 ARG A 148 ? ? 72.77 -1.97 13 1 GLU A 187 ? ? -171.68 141.99 14 1 PHE A 193 ? ? -81.52 45.57 15 1 LEU A 196 ? ? -93.06 48.52 16 1 ASN A 231 ? ? -119.07 -133.38 17 1 GLN A 232 ? ? -141.63 16.43 18 1 LEU A 233 ? ? -54.75 60.06 19 1 HIS A 234 ? ? -58.46 -86.82 20 1 LYS A 238 ? ? -34.49 -33.05 21 1 ASN A 255 ? ? -143.23 27.75 22 1 ILE A 257 ? ? -49.08 109.38 23 1 HIS A 262 ? ? -67.35 10.35 24 1 ALA A 278 ? ? 59.96 15.20 25 1 ASN A 279 ? ? -89.40 -150.13 26 1 ASN A 292 ? ? -114.55 72.73 27 1 LYS A 293 ? ? -89.04 33.96 28 1 GLU A 297 ? ? -175.20 114.06 29 1 ARG A 313 ? ? 45.85 27.51 30 1 GLN A 322 ? ? -120.40 -87.42 31 1 THR A 342 ? ? -72.28 24.32 32 1 ASN A 352 ? ? -107.36 -152.69 33 1 SER A 370 ? ? -159.57 85.66 34 1 ASN A 375 ? ? 58.50 74.25 35 1 PRO A 382 ? ? -27.08 120.39 36 1 PHE A 386 ? ? -93.10 35.61 37 1 THR A 389 ? ? -65.97 58.70 38 1 ASP A 399 ? ? 66.04 61.88 39 1 LEU A 416 ? ? -47.03 109.59 40 1 MET A 421 ? ? -140.79 27.71 41 1 ASN A 424 ? ? -114.29 -152.39 42 1 ARG A 441 ? ? -134.40 -32.94 43 1 ASN A 448 ? ? -125.61 -164.09 44 1 GLN A 453 ? ? 56.21 16.53 45 1 LEU A 461 ? ? -95.41 31.54 46 1 GLN A 462 ? ? 39.82 39.05 47 1 ASN A 483 ? ? -104.56 -157.02 48 1 PHE A 487 ? ? -175.70 136.69 49 1 ASN A 507 ? ? -103.43 -147.52 50 1 ALA A 518 ? ? -107.12 69.23 51 1 GLN A 522 ? ? -85.34 34.42 52 1 ARG A 524 ? ? 23.73 55.57 53 1 ASN A 532 ? ? -99.64 -144.65 54 1 ASP A 560 ? ? 58.92 74.01 55 1 PRO A 562 ? ? -75.04 34.11 56 1 CYS A 565 ? ? -106.32 55.77 57 1 GLN A 583 ? ? 66.38 -78.85 58 1 PRO A 607 ? ? -58.29 170.03 59 1 LEU A 616 ? ? -69.58 87.52 60 1 CYS A 650 ? ? -109.80 60.14 61 1 HIS A 651 ? ? -95.10 44.17 62 1 ASN A 654 ? ? -144.52 30.77 63 1 ASN A 678 ? ? -112.99 -156.71 64 1 LEU A 681 ? ? -131.92 -60.97 65 1 ASN A 703 ? ? -118.40 77.69 66 1 LEU A 719 ? ? -160.59 82.88 67 1 ASN A 724 ? ? -129.84 -162.78 68 1 ASP A 756 ? ? -133.35 -146.41 69 1 ASN A 777 ? ? -59.37 -9.14 70 1 LEU J 16 ? ? -160.09 76.53 71 1 GLU J 48 ? ? -94.90 -73.17 72 1 PRO J 96 ? ? -52.49 107.84 73 1 SER K 4 ? ? -89.89 43.84 74 1 ASN K 65 ? ? 36.53 72.55 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A MET 37 ? A MET 10 2 1 Y 1 A SER 38 ? A SER 11 3 1 Y 1 A ILE 39 ? A ILE 12 4 1 Y 1 A HIS 544 ? A HIS 517 5 1 Y 1 A LEU 545 ? A LEU 518 6 1 Y 1 A GLY 546 ? A GLY 519 7 1 Y 1 A GLU 547 ? A GLU 520 8 1 Y 1 A GLY 548 ? A GLY 521 9 1 Y 1 A TYR 549 ? A TYR 522 10 1 Y 1 A ASN 550 ? A ASN 523 11 1 Y 1 A ASN 551 ? A ASN 524 12 1 Y 1 A ASN 552 ? A ASN 525 13 1 Y 1 A PHE 622 ? A PHE 595 14 1 Y 1 A SER 623 ? A SER 596 15 1 Y 1 A ASP 624 ? A ASP 597 16 1 Y 1 A ASP 625 ? A ASP 598 17 1 Y 1 A PRO 626 ? A PRO 599 18 1 Y 1 A ARG 627 ? A ARG 600 19 1 Y 1 A GLU 628 ? A GLU 601 20 1 Y 1 A ARG 629 ? A ARG 602 21 1 Y 1 A ARG 739 ? A ARG 712 22 1 Y 1 A THR 740 ? A THR 713 23 1 Y 1 A MET 741 ? A MET 714 24 1 Y 1 A LYS 742 ? A LYS 715 25 1 Y 1 A GLU 785 ? A GLU 758 26 1 Y 1 A MET 786 ? A MET 759 27 1 Y 1 A ALA 801 ? A ALA 774 28 1 Y 1 A GLU 802 ? A GLU 775 29 1 Y 1 A THR 803 ? A THR 776 30 1 Y 1 A GLY 804 ? A GLY 777 31 1 Y 1 A HIS 805 ? A HIS 778 32 1 Y 1 A HIS 806 ? A HIS 779 33 1 Y 1 A HIS 807 ? A HIS 780 34 1 Y 1 A HIS 808 ? A HIS 781 35 1 Y 1 A HIS 809 ? A HIS 782 36 1 Y 1 A HIS 810 ? A HIS 783 37 1 Y 1 J VAL 1 ? B VAL 1 38 1 Y 1 J GLY 2 ? B GLY 2 39 1 Y 1 J GLY 3 ? B GLY 3 40 1 Y 1 J SER 4 ? B SER 4 41 1 Y 1 J PRO 19 ? B PRO 19 42 1 Y 1 J LYS 20 ? B LYS 20 43 1 Y 1 J LYS 21 ? B LYS 21 44 1 Y 1 J GLY 22 ? B GLY 22 45 1 Y 1 J LEU 23 ? B LEU 23 46 1 Y 1 J ARG 24 ? B ARG 24 47 1 Y 1 J ALA 25 ? B ALA 25 48 1 Y 1 J ASP 26 ? B ASP 26 49 1 Y 1 J ASP 27 ? B ASP 27 50 1 Y 1 J THR 28 ? B THR 28 51 1 Y 1 J TRP 29 ? B TRP 29 52 1 Y 1 J GLN 30 ? B GLN 30 53 1 Y 1 J LEU 31 ? B LEU 31 54 1 Y 1 J ILE 32 ? B ILE 32 55 1 Y 1 J VAL 33 ? B VAL 33 56 1 Y 1 J ASN 34 ? B ASN 34 57 1 Y 1 J ASN 35 ? B ASN 35 58 1 Y 1 J ASP 36 ? B ASP 36 59 1 Y 1 J GLU 37 ? B GLU 37 60 1 Y 1 J TYR 38 ? B TYR 38 61 1 Y 1 J LYS 39 ? B LYS 39 62 1 Y 1 J GLN 40 ? B GLN 40 63 1 Y 1 J ALA 41 ? B ALA 41 64 1 Y 1 J GLN 75 ? B GLN 75 65 1 Y 1 J THR 76 ? B THR 76 66 1 Y 1 J LEU 77 ? B LEU 77 67 1 Y 1 J ALA 78 ? B ALA 78 68 1 Y 1 J SER 79 ? B SER 79 69 1 Y 1 J ILE 80 ? B ILE 80 70 1 Y 1 J LYS 81 ? B LYS 81 71 1 Y 1 J SER 82 ? B SER 82 72 1 Y 1 J ASP 83 ? B ASP 83 73 1 Y 1 J GLY 84 ? B GLY 84 74 1 Y 1 J GLU 85 ? B GLU 85 75 1 Y 1 J LEU 86 ? B LEU 86 76 1 Y 1 J ASP 87 ? B ASP 87 77 1 Y 1 J VAL 88 ? B VAL 88 78 1 Y 1 J VAL 89 ? B VAL 89 79 1 Y 1 J GLN 90 ? B GLN 90 80 1 Y 1 J ASN 91 ? B ASN 91 81 1 Y 1 J SER 92 ? B SER 92 82 1 Y 1 J PHE 93 ? B PHE 93 83 1 Y 1 J HIS 110 ? B HIS 110 84 1 Y 1 J HIS 111 ? B HIS 111 85 1 Y 1 J HIS 112 ? B HIS 112 86 1 Y 1 J HIS 113 ? B HIS 113 87 1 Y 1 J HIS 114 ? B HIS 114 88 1 Y 1 K VAL 17 ? C VAL 17 89 1 Y 1 K TYR 18 ? C TYR 18 90 1 Y 1 K PRO 19 ? C PRO 19 91 1 Y 1 K LYS 20 ? C LYS 20 92 1 Y 1 K LYS 21 ? C LYS 21 93 1 Y 1 K GLY 22 ? C GLY 22 94 1 Y 1 K LEU 23 ? C LEU 23 95 1 Y 1 K ARG 24 ? C ARG 24 96 1 Y 1 K ALA 25 ? C ALA 25 97 1 Y 1 K ASP 26 ? C ASP 26 98 1 Y 1 K ASP 27 ? C ASP 27 99 1 Y 1 K THR 28 ? C THR 28 100 1 Y 1 K TRP 29 ? C TRP 29 101 1 Y 1 K GLN 30 ? C GLN 30 102 1 Y 1 K LEU 31 ? C LEU 31 103 1 Y 1 K ILE 32 ? C ILE 32 104 1 Y 1 K VAL 33 ? C VAL 33 105 1 Y 1 K ASN 34 ? C ASN 34 106 1 Y 1 K ASN 35 ? C ASN 35 107 1 Y 1 K ASP 36 ? C ASP 36 108 1 Y 1 K GLU 37 ? C GLU 37 109 1 Y 1 K TYR 38 ? C TYR 38 110 1 Y 1 K GLN 74 ? C GLN 74 111 1 Y 1 K GLN 75 ? C GLN 75 112 1 Y 1 K THR 76 ? C THR 76 113 1 Y 1 K LEU 77 ? C LEU 77 114 1 Y 1 K ALA 78 ? C ALA 78 115 1 Y 1 K SER 79 ? C SER 79 116 1 Y 1 K ILE 80 ? C ILE 80 117 1 Y 1 K LYS 81 ? C LYS 81 118 1 Y 1 K SER 82 ? C SER 82 119 1 Y 1 K ASP 83 ? C ASP 83 120 1 Y 1 K GLY 84 ? C GLY 84 121 1 Y 1 K GLU 85 ? C GLU 85 122 1 Y 1 K LEU 86 ? C LEU 86 123 1 Y 1 K ASP 87 ? C ASP 87 124 1 Y 1 K VAL 88 ? C VAL 88 125 1 Y 1 K VAL 89 ? C VAL 89 126 1 Y 1 K GLN 90 ? C GLN 90 127 1 Y 1 K ASN 91 ? C ASN 91 128 1 Y 1 K SER 92 ? C SER 92 129 1 Y 1 K PHE 93 ? C PHE 93 130 1 Y 1 K GLU 108 ? C GLU 108 131 1 Y 1 K HIS 109 ? C HIS 109 132 1 Y 1 K HIS 110 ? C HIS 110 133 1 Y 1 K HIS 111 ? C HIS 111 134 1 Y 1 K HIS 112 ? C HIS 112 135 1 Y 1 K HIS 113 ? C HIS 113 136 1 Y 1 K HIS 114 ? C HIS 114 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 3 N-ACETYL-D-GLUCOSAMINE NAG 4 BETA-D-MANNOSE BMA 5 ALPHA-D-MANNOSE MAN 6 '4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID' EPE #