data_4BFE # _entry.id 4BFE # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4BFE PDBE EBI-56175 WWPDB D_1290056175 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.content_type _pdbx_database_related.details PDB 4BFG unspecified 'STRUCTURE OF THE EXTRACELLULAR PORTION OF MOUSE CD200R' PDB 4BFI unspecified 'STRUCTURE OF THE COMPLEX OF THE EXTRACELLULAR PORTIONS OF MOUSE CD200R AND MOUSE CD200' # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 4BFE _pdbx_database_status.deposit_site PDBE _pdbx_database_status.process_site PDBE _pdbx_database_status.SG_entry . _pdbx_database_status.recvd_initial_deposition_date 2013-03-18 _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Hatherley, D.' 1 'Lea, S.M.' 2 'Johnson, S.' 3 'Barclay, A.N.' 4 # _citation.id primary _citation.title 'Structures of Cd200/Cd200 Receptor Family and Implications for Topology, Regulation, and Evolution' _citation.journal_abbrev Structure _citation.journal_volume 21 _citation.page_first 820 _citation.page_last ? _citation.year 2013 _citation.journal_id_ASTM STRUE6 _citation.country UK _citation.journal_id_ISSN 0969-2126 _citation.journal_id_CSD 2005 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 23602662 _citation.pdbx_database_id_DOI 10.1016/J.STR.2013.03.008 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Hatherley, D.' 1 primary 'Lea, S.M.' 2 primary 'Johnson, S.' 3 primary 'Barclay, A.N.' 4 # _cell.entry_id 4BFE _cell.length_a 157.590 _cell.length_b 157.590 _cell.length_c 167.940 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 120.00 _cell.Z_PDB 36 _cell.pdbx_unique_axis ? # _symmetry.entry_id 4BFE _symmetry.space_group_name_H-M 'P 65 2 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 179 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 4' 24337.213 3 ? ? 'EXTRACELLULAR DOMAIN, RESIDUES 26-238' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 15 ? ? ? ? 3 non-polymer syn CYSTEINE 121.158 3 ? ? ? ? 4 non-polymer syn 'SULFATE ION' 96.063 7 ? ? ? ? 5 non-polymer syn GLYCEROL 92.094 3 ? ? ? ? 6 water nat water 18.015 615 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name ;CD200 CELL SURFACE GLYCOPROTEIN RECEPTOR-LIKE 4, CD200 RECEPTOR-LIKE 4, CD200 CELL SURFACE GLYCOPROTEIN RECEPTOR-LIKE A, CD200RLA, CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR 4 ; # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;TDENQTIQNDSSSSLTQVNTTMSVQMDKKALLCCFSSPLINAVLITWIIKHRHLPSCTIAYNLDKKTNETSCLGRNITWA STPDHSPELQISAVALQHEGTYTCEIVTPEGNLEKVYDLQVLVPPEVTYFPGKNRTAVCEAMAGKPAAQISWTPDGDCVT KSESHSNGTVTVRSTCHWEQNNVSVVSCLVSHSTGNQSLSIELSQGTMTTPRSTRHHHHHH ; _entity_poly.pdbx_seq_one_letter_code_can ;TDENQTIQNDSSSSLTQVNTTMSVQMDKKALLCCFSSPLINAVLITWIIKHRHLPSCTIAYNLDKKTNETSCLGRNITWA STPDHSPELQISAVALQHEGTYTCEIVTPEGNLEKVYDLQVLVPPEVTYFPGKNRTAVCEAMAGKPAAQISWTPDGDCVT KSESHSNGTVTVRSTCHWEQNNVSVVSCLVSHSTGNQSLSIELSQGTMTTPRSTRHHHHHH ; _entity_poly.pdbx_strand_id A,B,C _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 THR n 1 2 ASP n 1 3 GLU n 1 4 ASN n 1 5 GLN n 1 6 THR n 1 7 ILE n 1 8 GLN n 1 9 ASN n 1 10 ASP n 1 11 SER n 1 12 SER n 1 13 SER n 1 14 SER n 1 15 LEU n 1 16 THR n 1 17 GLN n 1 18 VAL n 1 19 ASN n 1 20 THR n 1 21 THR n 1 22 MET n 1 23 SER n 1 24 VAL n 1 25 GLN n 1 26 MET n 1 27 ASP n 1 28 LYS n 1 29 LYS n 1 30 ALA n 1 31 LEU n 1 32 LEU n 1 33 CYS n 1 34 CYS n 1 35 PHE n 1 36 SER n 1 37 SER n 1 38 PRO n 1 39 LEU n 1 40 ILE n 1 41 ASN n 1 42 ALA n 1 43 VAL n 1 44 LEU n 1 45 ILE n 1 46 THR n 1 47 TRP n 1 48 ILE n 1 49 ILE n 1 50 LYS n 1 51 HIS n 1 52 ARG n 1 53 HIS n 1 54 LEU n 1 55 PRO n 1 56 SER n 1 57 CYS n 1 58 THR n 1 59 ILE n 1 60 ALA n 1 61 TYR n 1 62 ASN n 1 63 LEU n 1 64 ASP n 1 65 LYS n 1 66 LYS n 1 67 THR n 1 68 ASN n 1 69 GLU n 1 70 THR n 1 71 SER n 1 72 CYS n 1 73 LEU n 1 74 GLY n 1 75 ARG n 1 76 ASN n 1 77 ILE n 1 78 THR n 1 79 TRP n 1 80 ALA n 1 81 SER n 1 82 THR n 1 83 PRO n 1 84 ASP n 1 85 HIS n 1 86 SER n 1 87 PRO n 1 88 GLU n 1 89 LEU n 1 90 GLN n 1 91 ILE n 1 92 SER n 1 93 ALA n 1 94 VAL n 1 95 ALA n 1 96 LEU n 1 97 GLN n 1 98 HIS n 1 99 GLU n 1 100 GLY n 1 101 THR n 1 102 TYR n 1 103 THR n 1 104 CYS n 1 105 GLU n 1 106 ILE n 1 107 VAL n 1 108 THR n 1 109 PRO n 1 110 GLU n 1 111 GLY n 1 112 ASN n 1 113 LEU n 1 114 GLU n 1 115 LYS n 1 116 VAL n 1 117 TYR n 1 118 ASP n 1 119 LEU n 1 120 GLN n 1 121 VAL n 1 122 LEU n 1 123 VAL n 1 124 PRO n 1 125 PRO n 1 126 GLU n 1 127 VAL n 1 128 THR n 1 129 TYR n 1 130 PHE n 1 131 PRO n 1 132 GLY n 1 133 LYS n 1 134 ASN n 1 135 ARG n 1 136 THR n 1 137 ALA n 1 138 VAL n 1 139 CYS n 1 140 GLU n 1 141 ALA n 1 142 MET n 1 143 ALA n 1 144 GLY n 1 145 LYS n 1 146 PRO n 1 147 ALA n 1 148 ALA n 1 149 GLN n 1 150 ILE n 1 151 SER n 1 152 TRP n 1 153 THR n 1 154 PRO n 1 155 ASP n 1 156 GLY n 1 157 ASP n 1 158 CYS n 1 159 VAL n 1 160 THR n 1 161 LYS n 1 162 SER n 1 163 GLU n 1 164 SER n 1 165 HIS n 1 166 SER n 1 167 ASN n 1 168 GLY n 1 169 THR n 1 170 VAL n 1 171 THR n 1 172 VAL n 1 173 ARG n 1 174 SER n 1 175 THR n 1 176 CYS n 1 177 HIS n 1 178 TRP n 1 179 GLU n 1 180 GLN n 1 181 ASN n 1 182 ASN n 1 183 VAL n 1 184 SER n 1 185 VAL n 1 186 VAL n 1 187 SER n 1 188 CYS n 1 189 LEU n 1 190 VAL n 1 191 SER n 1 192 HIS n 1 193 SER n 1 194 THR n 1 195 GLY n 1 196 ASN n 1 197 GLN n 1 198 SER n 1 199 LEU n 1 200 SER n 1 201 ILE n 1 202 GLU n 1 203 LEU n 1 204 SER n 1 205 GLN n 1 206 GLY n 1 207 THR n 1 208 MET n 1 209 THR n 1 210 THR n 1 211 PRO n 1 212 ARG n 1 213 SER n 1 214 THR n 1 215 ARG n 1 216 HIS n 1 217 HIS n 1 218 HIS n 1 219 HIS n 1 220 HIS n 1 221 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'HOUSE MOUSE' _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene ? _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'MUS MUSCULUS' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 10090 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'CHINESE HAMSTER' _entity_src_gen.pdbx_host_org_scientific_name 'CRICETULUS GRISEUS' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 10029 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant LEC3.2.8.1 _entity_src_gen.pdbx_host_org_cell_line CHO _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type PLASMID _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name PEE14 _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MO2R4_MOUSE _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ? _struct_ref.pdbx_align_begin ? _struct_ref.pdbx_db_accession Q6XJV4 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4BFE A 1 ? 213 ? Q6XJV4 26 ? 238 ? 2 214 2 1 4BFE B 1 ? 213 ? Q6XJV4 26 ? 238 ? 2 214 3 1 4BFE C 1 ? 213 ? Q6XJV4 26 ? 238 ? 2 214 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4BFE THR A 214 ? UNP Q6XJV4 ? ? 'expression tag' 215 1 1 4BFE ARG A 215 ? UNP Q6XJV4 ? ? 'expression tag' 216 2 1 4BFE HIS A 216 ? UNP Q6XJV4 ? ? 'expression tag' 217 3 1 4BFE HIS A 217 ? UNP Q6XJV4 ? ? 'expression tag' 218 4 1 4BFE HIS A 218 ? UNP Q6XJV4 ? ? 'expression tag' 219 5 1 4BFE HIS A 219 ? UNP Q6XJV4 ? ? 'expression tag' 220 6 1 4BFE HIS A 220 ? UNP Q6XJV4 ? ? 'expression tag' 221 7 1 4BFE HIS A 221 ? UNP Q6XJV4 ? ? 'expression tag' 222 8 2 4BFE THR B 214 ? UNP Q6XJV4 ? ? 'expression tag' 215 9 2 4BFE ARG B 215 ? UNP Q6XJV4 ? ? 'expression tag' 216 10 2 4BFE HIS B 216 ? UNP Q6XJV4 ? ? 'expression tag' 217 11 2 4BFE HIS B 217 ? UNP Q6XJV4 ? ? 'expression tag' 218 12 2 4BFE HIS B 218 ? UNP Q6XJV4 ? ? 'expression tag' 219 13 2 4BFE HIS B 219 ? UNP Q6XJV4 ? ? 'expression tag' 220 14 2 4BFE HIS B 220 ? UNP Q6XJV4 ? ? 'expression tag' 221 15 2 4BFE HIS B 221 ? UNP Q6XJV4 ? ? 'expression tag' 222 16 3 4BFE THR C 214 ? UNP Q6XJV4 ? ? 'expression tag' 215 17 3 4BFE ARG C 215 ? UNP Q6XJV4 ? ? 'expression tag' 216 18 3 4BFE HIS C 216 ? UNP Q6XJV4 ? ? 'expression tag' 217 19 3 4BFE HIS C 217 ? UNP Q6XJV4 ? ? 'expression tag' 218 20 3 4BFE HIS C 218 ? UNP Q6XJV4 ? ? 'expression tag' 219 21 3 4BFE HIS C 219 ? UNP Q6XJV4 ? ? 'expression tag' 220 22 3 4BFE HIS C 220 ? UNP Q6XJV4 ? ? 'expression tag' 221 23 3 4BFE HIS C 221 ? UNP Q6XJV4 ? ? 'expression tag' 222 24 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 4BFE _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 3.72 _exptl_crystal.density_percent_sol 67 _exptl_crystal.description NONE # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method ? _exptl_crystal_grow.temp ? _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '2.0M AMMONIUM SULFATE, 0.1M SODIUM CACODYLATE, 0.2M SODIUM CHLORIDE, pH 6.5' # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC CCD' _diffrn_detector.pdbx_collection_date 2010-02-07 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9762 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ESRF BEAMLINE ID23-1' _diffrn_source.pdbx_synchrotron_site ESRF _diffrn_source.pdbx_synchrotron_beamline ID23-1 _diffrn_source.pdbx_wavelength 0.9762 _diffrn_source.pdbx_wavelength_list ? # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 4BFE _reflns.observed_criterion_sigma_I 2.0 _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 168.02 _reflns.d_resolution_high 2.50 _reflns.number_obs 42242 _reflns.number_all ? _reflns.percent_possible_obs 98.4 _reflns.pdbx_Rmerge_I_obs 0.07 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 13.00 _reflns.B_iso_Wilson_estimate 56.43 _reflns.pdbx_redundancy 3.6 # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 2.50 _reflns_shell.d_res_low 2.63 _reflns_shell.percent_possible_all 99.7 _reflns_shell.Rmerge_I_obs 0.49 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 2.20 _reflns_shell.pdbx_redundancy 3.5 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 4BFE _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 41716 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.0 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 15.00 _refine.ls_d_res_high 2.50 _refine.ls_percent_reflns_obs 97.51 _refine.ls_R_factor_obs 0.1731 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.1714 _refine.ls_R_factor_R_free 0.2053 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.07 _refine.ls_number_reflns_R_free 2115 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.9526 _refine.correlation_coeff_Fo_to_Fc_free 0.9332 _refine.B_iso_mean 48.52 _refine.aniso_B[1][1] -2.2215 _refine.aniso_B[2][2] -2.2215 _refine.aniso_B[3][3] 4.4431 _refine.aniso_B[1][2] 0.0000 _refine.aniso_B[1][3] 0.0000 _refine.aniso_B[2][3] 0.0000 _refine.solvent_model_details ? _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ? _refine.pdbx_starting_model NONE _refine.pdbx_method_to_determine_struct SIRAS _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.pdbx_overall_phase_error ? _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI 0.215 _refine.pdbx_overall_SU_R_free_Cruickshank_DPI 0.182 _refine.pdbx_overall_SU_R_Blow_DPI 0.246 _refine.pdbx_overall_SU_R_free_Blow_DPI 0.192 # _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_analyze.entry_id 4BFE _refine_analyze.Luzzati_coordinate_error_obs 0.274 _refine_analyze.Luzzati_sigma_a_obs ? _refine_analyze.Luzzati_d_res_low_obs ? _refine_analyze.Luzzati_coordinate_error_free ? _refine_analyze.Luzzati_sigma_a_free ? _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 4296 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 284 _refine_hist.number_atoms_solvent 615 _refine_hist.number_atoms_total 5195 _refine_hist.d_res_high 2.50 _refine_hist.d_res_low 15.00 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function t_bond_d 0.010 ? 2.00 4701 'X-RAY DIFFRACTION' HARMONIC t_angle_deg 1.23 ? 2.00 6456 'X-RAY DIFFRACTION' HARMONIC t_dihedral_angle_d ? ? 2.00 1626 'X-RAY DIFFRACTION' SINUSOIDAL t_incorr_chiral_ct ? ? ? ? 'X-RAY DIFFRACTION' ? t_pseud_angle ? ? ? ? 'X-RAY DIFFRACTION' ? t_trig_c_planes ? ? 2.00 110 'X-RAY DIFFRACTION' HARMONIC t_gen_planes ? ? 5.00 674 'X-RAY DIFFRACTION' HARMONIC t_it ? ? 20.00 4701 'X-RAY DIFFRACTION' HARMONIC t_nbd ? ? ? ? 'X-RAY DIFFRACTION' ? t_omega_torsion 3.53 ? ? ? 'X-RAY DIFFRACTION' ? t_other_torsion 16.94 ? ? ? 'X-RAY DIFFRACTION' ? t_improper_torsion ? ? ? ? 'X-RAY DIFFRACTION' ? t_chiral_improper_torsion ? ? 5.00 704 'X-RAY DIFFRACTION' SEMIHARMONIC t_sum_occupancies ? ? ? ? 'X-RAY DIFFRACTION' ? t_utility_distance ? ? ? ? 'X-RAY DIFFRACTION' ? t_utility_angle ? ? ? ? 'X-RAY DIFFRACTION' ? t_utility_torsion ? ? ? ? 'X-RAY DIFFRACTION' ? t_ideal_dist_contact ? ? 4.00 5121 'X-RAY DIFFRACTION' SEMIHARMONIC # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.50 _refine_ls_shell.d_res_low 2.56 _refine_ls_shell.number_reflns_R_work 2840 _refine_ls_shell.R_factor_R_work 0.2481 _refine_ls_shell.percent_reflns_obs 97.51 _refine_ls_shell.R_factor_R_free 0.2911 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free 4.60 _refine_ls_shell.number_reflns_R_free 137 _refine_ls_shell.number_reflns_all 2977 _refine_ls_shell.R_factor_all 0.2501 # loop_ _struct_ncs_oper.id _struct_ncs_oper.code _struct_ncs_oper.details _struct_ncs_oper.matrix[1][1] _struct_ncs_oper.matrix[1][2] _struct_ncs_oper.matrix[1][3] _struct_ncs_oper.matrix[2][1] _struct_ncs_oper.matrix[2][2] _struct_ncs_oper.matrix[2][3] _struct_ncs_oper.matrix[3][1] _struct_ncs_oper.matrix[3][2] _struct_ncs_oper.matrix[3][3] _struct_ncs_oper.vector[1] _struct_ncs_oper.vector[2] _struct_ncs_oper.vector[3] 1 given ? -0.271440 0.919280 -0.285030 -0.079140 0.273830 0.958520 0.959200 0.282740 -0.001580 14.82477 35.66623 -52.97234 2 given ? -0.249560 -0.102910 0.962880 0.936690 0.226550 0.266990 -0.245620 0.968550 0.039850 58.12469 -5.47250 -32.83457 # _struct.entry_id 4BFE _struct.title 'Structure of the extracellular portion of mouse CD200RLa' _struct.pdbx_descriptor 'CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 4' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 4BFE _struct_keywords.pdbx_keywords 'IMMUNE SYSTEM' _struct_keywords.text 'IMMUNE SYSTEM, PAIRED RECEPTOR, IG DOMAINS, VIRAL MIMICRY, LEUKAEMIA' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 1 ? D N N 2 ? E N N 2 ? F N N 3 ? G N N 4 ? H N N 4 ? I N N 2 ? J N N 2 ? K N N 2 ? L N N 2 ? M N N 2 ? N N N 3 ? O N N 4 ? P N N 4 ? Q N N 4 ? R N N 2 ? S N N 2 ? T N N 2 ? U N N 2 ? V N N 2 ? W N N 3 ? X N N 4 ? Y N N 4 ? Z N N 5 ? AA N N 5 ? BA N N 5 ? CA N N 2 ? DA N N 2 ? EA N N 2 ? FA N N 6 ? GA N N 6 ? HA N N 6 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ALA A 95 ? GLU A 99 ? ALA A 96 GLU A 100 5 ? 5 HELX_P HELX_P2 2 ALA B 95 ? GLU B 99 ? ALA B 96 GLU B 100 5 ? 5 HELX_P HELX_P3 3 ALA C 95 ? GLU C 99 ? ALA C 96 GLU C 100 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 33 SG ? ? ? 1_555 F CYS . SG ? ? A CYS 34 A CYS 1206 1_555 ? ? ? ? ? ? ? 2.047 ? disulf2 disulf ? ? A CYS 34 SG ? ? ? 1_555 A CYS 104 SG ? ? A CYS 35 A CYS 105 1_555 ? ? ? ? ? ? ? 2.045 ? disulf3 disulf ? ? A CYS 57 SG ? ? ? 1_555 A CYS 72 SG ? ? A CYS 58 A CYS 73 1_555 ? ? ? ? ? ? ? 2.079 ? disulf4 disulf ? ? A CYS 139 SG ? ? ? 1_555 A CYS 188 SG ? ? A CYS 140 A CYS 189 1_555 ? ? ? ? ? ? ? 2.018 ? disulf5 disulf ? ? A CYS 158 SG ? ? ? 1_555 A CYS 176 SG ? ? A CYS 159 A CYS 177 1_555 ? ? ? ? ? ? ? 2.043 ? disulf6 disulf ? ? B CYS 33 SG ? ? ? 1_555 N CYS . SG ? ? B CYS 34 B CYS 1206 1_555 ? ? ? ? ? ? ? 2.048 ? disulf7 disulf ? ? B CYS 34 SG ? ? ? 1_555 B CYS 104 SG ? ? B CYS 35 B CYS 105 1_555 ? ? ? ? ? ? ? 2.034 ? disulf8 disulf ? ? B CYS 57 SG ? ? ? 1_555 B CYS 72 SG ? ? B CYS 58 B CYS 73 1_555 ? ? ? ? ? ? ? 2.053 ? disulf9 disulf ? ? B CYS 139 SG ? ? ? 1_555 B CYS 188 SG ? ? B CYS 140 B CYS 189 1_555 ? ? ? ? ? ? ? 2.026 ? disulf10 disulf ? ? B CYS 158 SG ? ? ? 1_555 B CYS 176 SG ? ? B CYS 159 B CYS 177 1_555 ? ? ? ? ? ? ? 2.072 ? disulf11 disulf ? ? C CYS 33 SG ? ? ? 1_555 W CYS . SG ? ? C CYS 34 C CYS 1206 1_555 ? ? ? ? ? ? ? 2.046 ? disulf12 disulf ? ? C CYS 34 SG ? ? ? 1_555 C CYS 104 SG ? ? C CYS 35 C CYS 105 1_555 ? ? ? ? ? ? ? 2.022 ? disulf13 disulf ? ? C CYS 57 SG ? ? ? 1_555 C CYS 72 SG ? ? C CYS 58 C CYS 73 1_555 ? ? ? ? ? ? ? 2.073 ? disulf14 disulf ? ? C CYS 139 SG ? ? ? 1_555 C CYS 188 SG ? ? C CYS 140 C CYS 189 1_555 ? ? ? ? ? ? ? 2.025 ? disulf15 disulf ? ? C CYS 158 SG ? ? ? 1_555 C CYS 176 SG ? ? C CYS 159 C CYS 177 1_555 ? ? ? ? ? ? ? 2.038 ? covale1 covale ? ? A ASN 19 ND2 ? ? ? 1_555 K NAG . C1 ? ? A ASN 20 A NAG 2000 1_555 ? ? ? ? ? ? ? 1.432 ? covale2 covale ? ? A ASN 68 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 69 A NAG 690 1_555 ? ? ? ? ? ? ? 1.437 ? covale3 covale ? ? A ASN 76 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 77 A NAG 770 1_555 ? ? ? ? ? ? ? 1.430 ? covale4 covale ? ? A ASN 167 ND2 ? ? ? 1_555 I NAG . C1 ? ? A ASN 168 A NAG 1680 1_555 ? ? ? ? ? ? ? 1.431 ? covale5 covale ? ? A ASN 196 ND2 ? ? ? 1_555 J NAG . C1 ? ? A ASN 197 A NAG 1970 1_555 ? ? ? ? ? ? ? 1.434 ? covale6 covale ? ? B ASN 19 ND2 ? ? ? 1_555 T NAG . C1 ? ? B ASN 20 B NAG 2000 1_555 ? ? ? ? ? ? ? 1.432 ? covale7 covale ? ? B ASN 68 ND2 ? ? ? 1_555 L NAG . C1 ? ? B ASN 69 B NAG 690 1_555 ? ? ? ? ? ? ? 1.435 ? covale8 covale ? ? B ASN 76 ND2 ? ? ? 1_555 M NAG . C1 ? ? B ASN 77 B NAG 770 1_555 ? ? ? ? ? ? ? 1.430 ? covale9 covale ? ? B ASN 167 ND2 ? ? ? 1_555 R NAG . C1 ? ? B ASN 168 B NAG 1680 1_555 ? ? ? ? ? ? ? 1.430 ? covale10 covale ? ? B ASN 196 ND2 ? ? ? 1_555 S NAG . C1 ? ? B ASN 197 B NAG 1970 1_555 ? ? ? ? ? ? ? 1.434 ? covale11 covale ? ? C ASN 19 ND2 ? ? ? 1_555 EA NAG . C1 ? ? C ASN 20 C NAG 2000 1_555 ? ? ? ? ? ? ? 1.433 ? covale12 covale ? ? C ASN 68 ND2 ? ? ? 1_555 U NAG . C1 ? ? C ASN 69 C NAG 690 1_555 ? ? ? ? ? ? ? 1.426 ? covale13 covale ? ? C ASN 76 ND2 ? ? ? 1_555 V NAG . C1 ? ? C ASN 77 C NAG 770 1_555 ? ? ? ? ? ? ? 1.425 ? covale14 covale ? ? C ASN 167 ND2 ? ? ? 1_555 CA NAG . C1 ? ? C ASN 168 C NAG 1680 1_555 ? ? ? ? ? ? ? 1.428 ? covale15 covale ? ? C ASN 196 ND2 ? ? ? 1_555 DA NAG . C1 ? ? C ASN 197 C NAG 1970 1_555 ? ? ? ? ? ? ? 1.434 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 LYS 145 A . ? LYS 146 A PRO 146 A ? PRO 147 A 1 -2.17 2 THR 153 A . ? THR 154 A PRO 154 A ? PRO 155 A 1 -3.60 3 LYS 145 B . ? LYS 146 B PRO 146 B ? PRO 147 B 1 -1.67 4 THR 153 B . ? THR 154 B PRO 154 B ? PRO 155 B 1 -4.73 5 LYS 145 C . ? LYS 146 C PRO 146 C ? PRO 147 C 1 -2.94 6 THR 153 C . ? THR 154 C PRO 154 C ? PRO 155 C 1 -5.57 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA ? 2 ? AB ? 8 ? AC ? 6 ? AD ? 3 ? AE ? 4 ? AF ? 8 ? AG ? 5 ? BA ? 3 ? BB ? 4 ? BC ? 8 ? BD ? 5 ? CA ? 3 ? CB ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA 1 2 ? parallel AB 1 2 ? anti-parallel AB 2 3 ? anti-parallel AB 3 4 ? anti-parallel AB 4 5 ? anti-parallel AB 5 6 ? parallel AB 6 7 ? parallel AB 7 8 ? anti-parallel AC 1 2 ? anti-parallel AC 2 3 ? anti-parallel AC 3 4 ? anti-parallel AC 4 5 ? anti-parallel AC 5 6 ? parallel AD 1 2 ? anti-parallel AD 2 3 ? anti-parallel AE 1 2 ? anti-parallel AE 2 3 ? anti-parallel AE 3 4 ? anti-parallel AF 1 2 ? parallel AF 2 3 ? anti-parallel AF 3 4 ? anti-parallel AF 4 5 ? anti-parallel AF 5 6 ? anti-parallel AF 6 7 ? anti-parallel AF 7 8 ? anti-parallel AG 1 2 ? parallel AG 2 3 ? anti-parallel AG 3 4 ? anti-parallel AG 4 5 ? parallel BA 1 2 ? anti-parallel BA 2 3 ? anti-parallel BB 1 2 ? anti-parallel BB 2 3 ? anti-parallel BB 3 4 ? anti-parallel BC 1 2 ? parallel BC 2 3 ? anti-parallel BC 3 4 ? anti-parallel BC 4 5 ? anti-parallel BC 5 6 ? anti-parallel BC 6 7 ? anti-parallel BC 7 8 ? anti-parallel BD 1 2 ? parallel BD 2 3 ? anti-parallel BD 3 4 ? anti-parallel BD 4 5 ? parallel CA 1 2 ? anti-parallel CA 2 3 ? anti-parallel CB 1 2 ? anti-parallel CB 2 3 ? anti-parallel CB 3 4 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA 1 THR A 20 ? GLN A 25 ? THR A 21 GLN A 26 AA 2 GLY A 111 ? LEU A 122 ? GLY A 112 LEU A 123 AB 1 THR A 67 ? THR A 70 ? THR A 68 THR A 71 AB 2 CYS A 57 ? ASN A 62 ? CYS A 58 ASN A 63 AB 3 LEU A 44 ? LYS A 50 ? LEU A 45 LYS A 51 AB 4 GLY A 100 ? THR A 108 ? GLY A 101 THR A 109 AB 5 GLY A 111 ? LEU A 122 ? GLY A 112 LEU A 123 AB 6 GLN C 197 ? GLU C 202 ? GLN C 198 GLU C 203 AB 7 VAL C 185 ? SER C 191 ? VAL C 186 SER C 192 AB 8 GLN C 149 ? THR C 153 ? GLN C 150 THR C 154 AC 1 THR A 67 ? THR A 70 ? THR A 68 THR A 71 AC 2 CYS A 57 ? ASN A 62 ? CYS A 58 ASN A 63 AC 3 LEU A 44 ? LYS A 50 ? LEU A 45 LYS A 51 AC 4 GLY A 100 ? THR A 108 ? GLY A 101 THR A 109 AC 5 GLY A 111 ? LEU A 122 ? GLY A 112 LEU A 123 AC 6 THR A 20 ? GLN A 25 ? THR A 21 GLN A 26 AD 1 ALA A 30 ? CYS A 33 ? ALA A 31 CYS A 34 AD 2 GLU A 88 ? ILE A 91 ? GLU A 89 ILE A 92 AD 3 ILE A 77 ? TRP A 79 ? ILE A 78 TRP A 80 AE 1 GLU A 126 ? PRO A 131 ? GLU A 127 PRO A 132 AE 2 THR A 136 ? GLY A 144 ? THR A 137 GLY A 145 AE 3 VAL A 170 ? HIS A 177 ? VAL A 171 HIS A 178 AE 4 ASP A 157 ? SER A 164 ? ASP A 158 SER A 165 AF 1 GLN A 149 ? THR A 153 ? GLN A 150 THR A 154 AF 2 VAL A 185 ? SER A 191 ? VAL A 186 SER A 192 AF 3 GLN A 197 ? GLU A 202 ? GLN A 198 GLU A 203 AF 4 GLY B 111 ? LEU B 122 ? GLY B 112 LEU B 123 AF 5 GLY B 100 ? THR B 108 ? GLY B 101 THR B 109 AF 6 LEU B 44 ? LYS B 50 ? LEU B 45 LYS B 51 AF 7 CYS B 57 ? ASN B 62 ? CYS B 58 ASN B 63 AF 8 THR B 67 ? THR B 70 ? THR B 68 THR B 71 AG 1 GLN A 149 ? THR A 153 ? GLN A 150 THR A 154 AG 2 VAL A 185 ? SER A 191 ? VAL A 186 SER A 192 AG 3 GLN A 197 ? GLU A 202 ? GLN A 198 GLU A 203 AG 4 GLY B 111 ? LEU B 122 ? GLY B 112 LEU B 123 AG 5 THR B 20 ? GLN B 25 ? THR B 21 GLN B 26 BA 1 ALA B 30 ? CYS B 33 ? ALA B 31 CYS B 34 BA 2 GLU B 88 ? ILE B 91 ? GLU B 89 ILE B 92 BA 3 ILE B 77 ? TRP B 79 ? ILE B 78 TRP B 80 BB 1 GLU B 126 ? GLY B 132 ? GLU B 127 GLY B 133 BB 2 THR B 136 ? GLY B 144 ? THR B 137 GLY B 145 BB 3 VAL B 170 ? HIS B 177 ? VAL B 171 HIS B 178 BB 4 ASP B 157 ? SER B 164 ? ASP B 158 SER B 165 BC 1 GLN B 149 ? THR B 153 ? GLN B 150 THR B 154 BC 2 VAL B 185 ? SER B 191 ? VAL B 186 SER B 192 BC 3 GLN B 197 ? GLU B 202 ? GLN B 198 GLU B 203 BC 4 GLY C 111 ? LEU C 122 ? GLY C 112 LEU C 123 BC 5 GLY C 100 ? THR C 108 ? GLY C 101 THR C 109 BC 6 LEU C 44 ? LYS C 50 ? LEU C 45 LYS C 51 BC 7 CYS C 57 ? ASN C 62 ? CYS C 58 ASN C 63 BC 8 THR C 67 ? THR C 70 ? THR C 68 THR C 71 BD 1 GLN B 149 ? THR B 153 ? GLN B 150 THR B 154 BD 2 VAL B 185 ? SER B 191 ? VAL B 186 SER B 192 BD 3 GLN B 197 ? GLU B 202 ? GLN B 198 GLU B 203 BD 4 GLY C 111 ? LEU C 122 ? GLY C 112 LEU C 123 BD 5 THR C 20 ? GLN C 25 ? THR C 21 GLN C 26 CA 1 ALA C 30 ? CYS C 33 ? ALA C 31 CYS C 34 CA 2 GLU C 88 ? ILE C 91 ? GLU C 89 ILE C 92 CA 3 ILE C 77 ? TRP C 79 ? ILE C 78 TRP C 80 CB 1 GLU C 126 ? PRO C 131 ? GLU C 127 PRO C 132 CB 2 THR C 136 ? GLY C 144 ? THR C 137 GLY C 145 CB 3 VAL C 170 ? HIS C 177 ? VAL C 171 HIS C 178 CB 4 ASP C 157 ? SER C 164 ? ASP C 158 SER C 165 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA 1 2 N THR A 20 ? N THR A 21 O VAL A 116 ? O VAL A 117 AB 1 2 N GLU A 69 ? N GLU A 70 O ALA A 60 ? O ALA A 61 AB 2 3 N TYR A 61 ? N TYR A 62 O ILE A 45 ? O ILE A 46 AB 3 4 N LYS A 50 ? N LYS A 51 O THR A 101 ? O THR A 102 AB 4 5 N THR A 108 ? N THR A 109 O GLY A 111 ? O GLY A 112 AB 5 6 N GLU A 114 ? N GLU A 115 O SER C 200 ? O SER C 201 AB 6 7 N ILE C 201 ? N ILE C 202 O VAL C 186 ? O VAL C 187 AB 7 8 N SER C 191 ? N SER C 192 O GLN C 149 ? O GLN C 150 AC 1 2 N GLU A 69 ? N GLU A 70 O ALA A 60 ? O ALA A 61 AC 2 3 N TYR A 61 ? N TYR A 62 O ILE A 45 ? O ILE A 46 AC 3 4 N LYS A 50 ? N LYS A 51 O THR A 101 ? O THR A 102 AC 4 5 N THR A 108 ? N THR A 109 O GLY A 111 ? O GLY A 112 AC 5 6 N ASP A 118 ? N ASP A 119 O THR A 20 ? O THR A 21 AD 1 2 N LEU A 32 ? N LEU A 33 O LEU A 89 ? O LEU A 90 AD 2 3 N GLN A 90 ? N GLN A 91 O THR A 78 ? O THR A 79 AE 1 2 N PHE A 130 ? N PHE A 131 O VAL A 138 ? O VAL A 139 AE 2 3 N GLY A 144 ? N GLY A 145 O VAL A 170 ? O VAL A 171 AE 3 4 N HIS A 177 ? N HIS A 178 O ASP A 157 ? O ASP A 158 AF 1 2 N THR A 153 ? N THR A 154 O SER A 187 ? O SER A 188 AF 2 3 N VAL A 190 ? N VAL A 191 O GLN A 197 ? O GLN A 198 AF 3 4 N GLU A 202 ? N GLU A 203 O ASN B 112 ? O ASN B 113 AF 4 5 N LEU B 119 ? N LEU B 120 O GLY B 100 ? O GLY B 101 AF 5 6 N VAL B 107 ? N VAL B 108 O LEU B 44 ? O LEU B 45 AF 6 7 N ILE B 49 ? N ILE B 50 O CYS B 57 ? O CYS B 58 AF 7 8 N ASN B 62 ? N ASN B 63 O THR B 67 ? O THR B 68 AG 1 2 N THR A 153 ? N THR A 154 O SER A 187 ? O SER A 188 AG 2 3 N VAL A 190 ? N VAL A 191 O GLN A 197 ? O GLN A 198 AG 3 4 N GLU A 202 ? N GLU A 203 O ASN B 112 ? O ASN B 113 AG 4 5 N ASP B 118 ? N ASP B 119 O THR B 20 ? O THR B 21 BA 1 2 N LEU B 32 ? N LEU B 33 O LEU B 89 ? O LEU B 90 BA 2 3 N GLN B 90 ? N GLN B 91 O THR B 78 ? O THR B 79 BB 1 2 N GLY B 132 ? N GLY B 133 O THR B 136 ? O THR B 137 BB 2 3 N GLY B 144 ? N GLY B 145 O VAL B 170 ? O VAL B 171 BB 3 4 N HIS B 177 ? N HIS B 178 O ASP B 157 ? O ASP B 158 BC 1 2 N THR B 153 ? N THR B 154 O SER B 187 ? O SER B 188 BC 2 3 N VAL B 190 ? N VAL B 191 O GLN B 197 ? O GLN B 198 BC 3 4 N GLU B 202 ? N GLU B 203 O ASN C 112 ? O ASN C 113 BC 4 5 N LEU C 119 ? N LEU C 120 O GLY C 100 ? O GLY C 101 BC 5 6 N VAL C 107 ? N VAL C 108 O LEU C 44 ? O LEU C 45 BC 6 7 N ILE C 49 ? N ILE C 50 O CYS C 57 ? O CYS C 58 BC 7 8 N ASN C 62 ? N ASN C 63 O THR C 67 ? O THR C 68 BD 1 2 N THR B 153 ? N THR B 154 O SER B 187 ? O SER B 188 BD 2 3 N VAL B 190 ? N VAL B 191 O GLN B 197 ? O GLN B 198 BD 3 4 N GLU B 202 ? N GLU B 203 O ASN C 112 ? O ASN C 113 BD 4 5 N ASP C 118 ? N ASP C 119 O THR C 20 ? O THR C 21 CA 1 2 N LEU C 32 ? N LEU C 33 O LEU C 89 ? O LEU C 90 CA 2 3 N GLN C 90 ? N GLN C 91 O THR C 78 ? O THR C 79 CB 1 2 N PHE C 130 ? N PHE C 131 O VAL C 138 ? O VAL C 139 CB 2 3 N GLY C 144 ? N GLY C 145 O VAL C 170 ? O VAL C 171 CB 3 4 N HIS C 177 ? N HIS C 178 O ASP C 157 ? O ASP C 158 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CYS A 1206' AC2 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE CYS B 1206' AC3 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CYS C 1206' AC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE SO4 C 1207' AC5 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE SO4 A 1207' AC6 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE SO4 B 1207' AC7 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE SO4 B 1208' AC8 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE SO4 C 1208' AC9 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE SO4 A 1208' BC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE GOL C 1209' BC2 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE GOL C 1210' BC3 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE GOL C 1211' BC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE SO4 B 1209' BC5 Software ? ? ? ? 3 'Binding site for Mono-Saccharide NAG A2000 bound to ASN A 20' BC6 Software ? ? ? ? 3 'Binding site for Mono-Saccharide NAG A 690 bound to ASN A 69' BC7 Software ? ? ? ? 3 'Binding site for Mono-Saccharide NAG A 770 bound to ASN A 77' BC8 Software ? ? ? ? 7 'Binding site for Mono-Saccharide NAG A1680 bound to ASN A 168' BC9 Software ? ? ? ? 3 'Binding site for Mono-Saccharide NAG A1970 bound to ASN A 197' CC1 Software ? ? ? ? 4 'Binding site for Mono-Saccharide NAG B2000 bound to ASN B 20' CC2 Software ? ? ? ? 7 'Binding site for Mono-Saccharide NAG B 690 bound to ASN B 69' CC3 Software ? ? ? ? 5 'Binding site for Mono-Saccharide NAG B 770 bound to ASN B 77' CC4 Software ? ? ? ? 9 'Binding site for Mono-Saccharide NAG B1680 bound to ASN B 168' CC5 Software ? ? ? ? 4 'Binding site for Mono-Saccharide NAG B1970 bound to ASN B 197' CC6 Software ? ? ? ? 4 'Binding site for Mono-Saccharide NAG C2000 bound to ASN C 20' CC7 Software ? ? ? ? 8 'Binding site for Mono-Saccharide NAG C 690 bound to ASN C 69' CC8 Software ? ? ? ? 6 'Binding site for Mono-Saccharide NAG C 770 bound to ASN C 77' CC9 Software ? ? ? ? 12 'Binding site for Mono-Saccharide NAG C1680 bound to ASN C 168' DC1 Software ? ? ? ? 3 'Binding site for Mono-Saccharide NAG C1970 bound to ASN C 197' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 CYS A 33 ? CYS A 34 . ? 1_555 ? 2 AC1 4 SER A 86 ? SER A 87 . ? 1_555 ? 3 AC1 4 GLU A 88 ? GLU A 89 . ? 1_555 ? 4 AC1 4 HOH FA . ? HOH A 2085 . ? 1_555 ? 5 AC2 2 CYS B 33 ? CYS B 34 . ? 1_555 ? 6 AC2 2 SER B 36 ? SER B 37 . ? 1_555 ? 7 AC3 6 CYS C 33 ? CYS C 34 . ? 1_555 ? 8 AC3 6 PHE C 35 ? PHE C 36 . ? 1_555 ? 9 AC3 6 SER C 36 ? SER C 37 . ? 1_555 ? 10 AC3 6 SER C 86 ? SER C 87 . ? 1_555 ? 11 AC3 6 PRO C 87 ? PRO C 88 . ? 1_555 ? 12 AC3 6 GLU C 88 ? GLU C 89 . ? 1_555 ? 13 AC4 5 PRO C 55 ? PRO C 56 . ? 12_554 ? 14 AC4 5 HIS C 165 ? HIS C 166 . ? 1_555 ? 15 AC4 5 SER C 166 ? SER C 167 . ? 1_555 ? 16 AC4 5 HOH HA . ? HOH C 2075 . ? 12_554 ? 17 AC4 5 HOH HA . ? HOH C 2181 . ? 1_555 ? 18 AC5 3 HIS A 165 ? HIS A 166 . ? 1_555 ? 19 AC5 3 SER A 166 ? SER A 167 . ? 1_555 ? 20 AC5 3 NAG I . ? NAG A 1680 . ? 1_555 ? 21 AC6 5 HIS B 165 ? HIS B 166 . ? 1_555 ? 22 AC6 5 SER B 166 ? SER B 167 . ? 1_555 ? 23 AC6 5 NAG R . ? NAG B 1680 . ? 1_555 ? 24 AC6 5 HOH GA . ? HOH B 2160 . ? 1_555 ? 25 AC6 5 LYS C 65 ? LYS C 66 . ? 7_554 ? 26 AC7 4 THR B 78 ? THR B 79 . ? 1_555 ? 27 AC7 4 TRP B 79 ? TRP B 80 . ? 1_555 ? 28 AC7 4 NAG L . ? NAG B 690 . ? 1_555 ? 29 AC7 4 HOH GA . ? HOH B 2192 . ? 1_555 ? 30 AC8 5 ASP C 84 ? ASP C 85 . ? 1_555 ? 31 AC8 5 HIS C 85 ? HIS C 86 . ? 1_555 ? 32 AC8 5 SER C 86 ? SER C 87 . ? 1_555 ? 33 AC8 5 HOH HA . ? HOH C 2116 . ? 1_555 ? 34 AC8 5 HOH HA . ? HOH C 2222 . ? 1_555 ? 35 AC9 5 ASP A 84 ? ASP A 85 . ? 1_555 ? 36 AC9 5 HIS A 85 ? HIS A 86 . ? 1_555 ? 37 AC9 5 SER A 86 ? SER A 87 . ? 1_555 ? 38 AC9 5 HOH FA . ? HOH A 2079 . ? 1_555 ? 39 AC9 5 HOH FA . ? HOH A 2081 . ? 1_555 ? 40 BC1 6 HOH FA . ? HOH A 2031 . ? 12_554 ? 41 BC1 6 CYS C 72 ? CYS C 73 . ? 1_555 ? 42 BC1 6 LEU C 73 ? LEU C 74 . ? 1_555 ? 43 BC1 6 GLY C 74 ? GLY C 75 . ? 1_555 ? 44 BC1 6 HOH HA . ? HOH C 2096 . ? 1_555 ? 45 BC1 6 HOH HA . ? HOH C 2223 . ? 1_555 ? 46 BC2 2 VAL C 43 ? VAL C 44 . ? 1_555 ? 47 BC2 2 PRO C 109 ? PRO C 110 . ? 1_555 ? 48 BC3 4 PRO C 154 ? PRO C 155 . ? 1_555 ? 49 BC3 4 ASP C 155 ? ASP C 156 . ? 1_555 ? 50 BC3 4 HOH HA . ? HOH C 2168 . ? 1_555 ? 51 BC3 4 HOH HA . ? HOH C 2224 . ? 1_555 ? 52 BC4 5 ASP B 84 ? ASP B 85 . ? 1_555 ? 53 BC4 5 HIS B 85 ? HIS B 86 . ? 1_555 ? 54 BC4 5 SER B 86 ? SER B 87 . ? 1_555 ? 55 BC4 5 HOH GA . ? HOH B 2094 . ? 1_555 ? 56 BC4 5 HOH GA . ? HOH B 2193 . ? 1_555 ? 57 BC5 3 ASN A 19 ? ASN A 20 . ? 1_555 ? 58 BC5 3 THR A 101 ? THR A 102 . ? 1_555 ? 59 BC5 3 ASP A 118 ? ASP A 119 . ? 1_555 ? 60 BC6 3 TYR A 61 ? TYR A 62 . ? 1_555 ? 61 BC6 3 ASN A 68 ? ASN A 69 . ? 1_555 ? 62 BC6 3 HOH FA . ? HOH A 2169 . ? 1_555 ? 63 BC7 3 GLY A 74 ? GLY A 75 . ? 1_555 ? 64 BC7 3 ASN A 76 ? ASN A 77 . ? 1_555 ? 65 BC7 3 HOH FA . ? HOH A 2075 . ? 1_555 ? 66 BC8 7 LEU A 96 ? LEU A 97 . ? 1_555 ? 67 BC8 7 HIS A 165 ? HIS A 166 . ? 1_555 ? 68 BC8 7 ASN A 167 ? ASN A 168 . ? 1_555 ? 69 BC8 7 THR A 169 ? THR A 170 . ? 1_555 ? 70 BC8 7 SO4 G . ? SO4 A 1207 . ? 1_555 ? 71 BC8 7 HOH FA . ? HOH A 2120 . ? 1_555 ? 72 BC8 7 HOH FA . ? HOH A 2171 . ? 1_555 ? 73 BC9 3 LEU A 189 ? LEU A 190 . ? 1_555 ? 74 BC9 3 SER A 191 ? SER A 192 . ? 1_555 ? 75 BC9 3 ASN A 196 ? ASN A 197 . ? 1_555 ? 76 CC1 4 GLN B 17 ? GLN B 18 . ? 1_555 ? 77 CC1 4 ASN B 19 ? ASN B 20 . ? 1_555 ? 78 CC1 4 THR B 101 ? THR B 102 . ? 1_555 ? 79 CC1 4 ASP B 118 ? ASP B 119 . ? 1_555 ? 80 CC2 7 SER A 71 ? SER A 72 . ? 6_554 ? 81 CC2 7 TYR B 61 ? TYR B 62 . ? 1_555 ? 82 CC2 7 ASN B 68 ? ASN B 69 . ? 1_555 ? 83 CC2 7 THR B 82 ? THR B 83 . ? 1_555 ? 84 CC2 7 SO4 P . ? SO4 B 1208 . ? 1_555 ? 85 CC2 7 HOH GA . ? HOH B 2058 . ? 1_555 ? 86 CC2 7 HOH GA . ? HOH B 2064 . ? 1_555 ? 87 CC3 5 GLY B 74 ? GLY B 75 . ? 1_555 ? 88 CC3 5 ASN B 76 ? ASN B 77 . ? 1_555 ? 89 CC3 5 SER B 92 ? SER B 93 . ? 1_555 ? 90 CC3 5 HOH GA . ? HOH B 2088 . ? 1_555 ? 91 CC3 5 HOH GA . ? HOH B 2189 . ? 1_555 ? 92 CC4 9 LEU B 96 ? LEU B 97 . ? 1_555 ? 93 CC4 9 HIS B 165 ? HIS B 166 . ? 1_555 ? 94 CC4 9 ASN B 167 ? ASN B 168 . ? 1_555 ? 95 CC4 9 THR B 169 ? THR B 170 . ? 1_555 ? 96 CC4 9 SO4 O . ? SO4 B 1207 . ? 1_555 ? 97 CC4 9 HOH GA . ? HOH B 2128 . ? 1_555 ? 98 CC4 9 HOH GA . ? HOH B 2194 . ? 1_555 ? 99 CC4 9 HOH GA . ? HOH B 2195 . ? 1_555 ? 100 CC4 9 LYS C 65 ? LYS C 66 . ? 7_554 ? 101 CC5 4 LEU B 189 ? LEU B 190 . ? 1_555 ? 102 CC5 4 SER B 191 ? SER B 192 . ? 1_555 ? 103 CC5 4 ASN B 196 ? ASN B 197 . ? 1_555 ? 104 CC5 4 HOH GA . ? HOH B 2196 . ? 1_555 ? 105 CC6 4 ASN C 19 ? ASN C 20 . ? 1_555 ? 106 CC6 4 THR C 101 ? THR C 102 . ? 1_555 ? 107 CC6 4 ASP C 118 ? ASP C 119 . ? 1_555 ? 108 CC6 4 HOH HA . ? HOH C 2002 . ? 1_555 ? 109 CC7 8 PRO A 38 ? PRO A 39 . ? 12_554 ? 110 CC7 8 ILE A 40 ? ILE A 41 . ? 12_554 ? 111 CC7 8 ASN A 41 ? ASN A 42 . ? 12_554 ? 112 CC7 8 ASP A 84 ? ASP A 85 . ? 12_554 ? 113 CC7 8 HIS A 85 ? HIS A 86 . ? 12_554 ? 114 CC7 8 TYR C 61 ? TYR C 62 . ? 1_555 ? 115 CC7 8 ASN C 68 ? ASN C 69 . ? 1_555 ? 116 CC7 8 THR C 82 ? THR C 83 . ? 1_555 ? 117 CC8 6 MET C 26 ? MET C 27 . ? 12_554 ? 118 CC8 6 ASP C 27 ? ASP C 28 . ? 12_554 ? 119 CC8 6 GLY C 74 ? GLY C 75 . ? 1_555 ? 120 CC8 6 ASN C 76 ? ASN C 77 . ? 1_555 ? 121 CC8 6 SER C 92 ? SER C 93 . ? 1_555 ? 122 CC8 6 HOH HA . ? HOH C 2219 . ? 1_555 ? 123 CC9 12 PRO C 55 ? PRO C 56 . ? 12_554 ? 124 CC9 12 SER C 56 ? SER C 57 . ? 12_554 ? 125 CC9 12 SER C 71 ? SER C 72 . ? 12_554 ? 126 CC9 12 LEU C 73 ? LEU C 74 . ? 12_554 ? 127 CC9 12 ARG C 75 ? ARG C 76 . ? 12_554 ? 128 CC9 12 LEU C 96 ? LEU C 97 . ? 1_555 ? 129 CC9 12 HIS C 165 ? HIS C 166 . ? 1_555 ? 130 CC9 12 ASN C 167 ? ASN C 168 . ? 1_555 ? 131 CC9 12 THR C 169 ? THR C 170 . ? 1_555 ? 132 CC9 12 HOH HA . ? HOH C 2105 . ? 12_554 ? 133 CC9 12 HOH HA . ? HOH C 2126 . ? 12_554 ? 134 CC9 12 HOH HA . ? HOH C 2153 . ? 1_555 ? 135 DC1 3 LEU C 189 ? LEU C 190 . ? 1_555 ? 136 DC1 3 SER C 191 ? SER C 192 . ? 1_555 ? 137 DC1 3 ASN C 196 ? ASN C 197 . ? 1_555 ? # _database_PDB_matrix.entry_id 4BFE _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 4BFE _atom_sites.fract_transf_matrix[1][1] 0.006346 _atom_sites.fract_transf_matrix[1][2] 0.003664 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.007327 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.005955 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLN A 1 17 ? 60.403 35.012 27.955 1.00 76.34 ? 18 GLN A N 1 ATOM 2 C CA . GLN A 1 17 ? 60.595 36.428 28.309 1.00 76.15 ? 18 GLN A CA 1 ATOM 3 C C . GLN A 1 17 ? 60.520 37.333 27.072 1.00 76.16 ? 18 GLN A C 1 ATOM 4 O O . GLN A 1 17 ? 59.558 38.098 26.991 1.00 76.87 ? 18 GLN A O 1 ATOM 5 C CB . GLN A 1 17 ? 61.863 36.684 29.158 1.00 77.94 ? 18 GLN A CB 1 ATOM 6 C CG . GLN A 1 17 ? 61.544 36.998 30.629 1.00 108.86 ? 18 GLN A CG 1 ATOM 7 C CD . GLN A 1 17 ? 62.625 37.788 31.346 1.00 138.91 ? 18 GLN A CD 1 ATOM 8 O OE1 . GLN A 1 17 ? 63.826 37.473 31.288 1.00 136.09 ? 18 GLN A OE1 1 ATOM 9 N NE2 . GLN A 1 17 ? 62.211 38.807 32.090 1.00 132.48 ? 18 GLN A NE2 1 ATOM 10 N N . VAL A 1 18 ? 61.501 37.247 26.104 1.00 67.17 ? 19 VAL A N 1 ATOM 11 C CA . VAL A 1 18 ? 61.402 38.012 24.840 1.00 63.66 ? 19 VAL A CA 1 ATOM 12 C C . VAL A 1 18 ? 60.250 37.374 24.025 1.00 61.77 ? 19 VAL A C 1 ATOM 13 O O . VAL A 1 18 ? 60.253 36.160 23.762 1.00 59.48 ? 19 VAL A O 1 ATOM 14 C CB . VAL A 1 18 ? 62.706 38.193 23.992 1.00 65.16 ? 19 VAL A CB 1 ATOM 15 C CG1 . VAL A 1 18 ? 62.402 38.873 22.651 1.00 63.87 ? 19 VAL A CG1 1 ATOM 16 C CG2 . VAL A 1 18 ? 63.757 38.990 24.754 1.00 64.49 ? 19 VAL A CG2 1 ATOM 17 N N . ASN A 1 19 ? 59.248 38.203 23.697 1.00 53.94 ? 20 ASN A N 1 ATOM 18 C CA . ASN A 1 19 ? 58.074 37.756 22.985 1.00 51.35 ? 20 ASN A CA 1 ATOM 19 C C . ASN A 1 19 ? 57.421 38.824 22.121 1.00 49.71 ? 20 ASN A C 1 ATOM 20 O O . ASN A 1 19 ? 57.668 40.022 22.269 1.00 48.35 ? 20 ASN A O 1 ATOM 21 C CB . ASN A 1 19 ? 57.059 37.159 23.978 1.00 53.14 ? 20 ASN A CB 1 ATOM 22 C CG . ASN A 1 19 ? 56.245 38.167 24.748 1.00 87.80 ? 20 ASN A CG 1 ATOM 23 O OD1 . ASN A 1 19 ? 55.291 38.760 24.218 1.00 75.90 ? 20 ASN A OD1 1 ATOM 24 N ND2 . ASN A 1 19 ? 56.594 38.368 26.018 1.00 96.54 ? 20 ASN A ND2 1 ATOM 25 N N . THR A 1 20 ? 56.540 38.365 21.251 1.00 44.79 ? 21 THR A N 1 ATOM 26 C CA . THR A 1 20 ? 55.697 39.187 20.411 1.00 44.08 ? 21 THR A CA 1 ATOM 27 C C . THR A 1 20 ? 54.296 39.193 21.075 1.00 46.34 ? 21 THR A C 1 ATOM 28 O O . THR A 1 20 ? 53.696 38.132 21.267 1.00 43.43 ? 21 THR A O 1 ATOM 29 C CB . THR A 1 20 ? 55.653 38.603 18.990 1.00 49.69 ? 21 THR A CB 1 ATOM 30 O OG1 . THR A 1 20 ? 56.983 38.414 18.502 1.00 53.55 ? 21 THR A OG1 1 ATOM 31 C CG2 . THR A 1 20 ? 54.846 39.449 18.026 1.00 42.97 ? 21 THR A CG2 1 ATOM 32 N N . THR A 1 21 ? 53.789 40.381 21.441 1.00 44.97 ? 22 THR A N 1 ATOM 33 C CA . THR A 1 21 ? 52.423 40.483 21.939 1.00 45.74 ? 22 THR A CA 1 ATOM 34 C C . THR A 1 21 ? 51.534 40.588 20.714 1.00 50.42 ? 22 THR A C 1 ATOM 35 O O . THR A 1 21 ? 51.843 41.335 19.797 1.00 52.75 ? 22 THR A O 1 ATOM 36 C CB . THR A 1 21 ? 52.233 41.593 22.965 1.00 58.30 ? 22 THR A CB 1 ATOM 37 O OG1 . THR A 1 21 ? 53.084 41.307 24.073 1.00 65.29 ? 22 THR A OG1 1 ATOM 38 C CG2 . THR A 1 21 ? 50.798 41.649 23.485 1.00 57.48 ? 22 THR A CG2 1 ATOM 39 N N . MET A 1 22 ? 50.500 39.773 20.651 1.00 45.69 ? 23 MET A N 1 ATOM 40 C CA . MET A 1 22 ? 49.588 39.735 19.539 1.00 45.20 ? 23 MET A CA 1 ATOM 41 C C . MET A 1 22 ? 48.159 39.821 20.082 1.00 46.80 ? 23 MET A C 1 ATOM 42 O O . MET A 1 22 ? 47.820 39.107 21.027 1.00 45.87 ? 23 MET A O 1 ATOM 43 C CB . MET A 1 22 ? 49.820 38.435 18.778 1.00 49.16 ? 23 MET A CB 1 ATOM 44 C CG . MET A 1 22 ? 49.098 38.371 17.478 1.00 55.65 ? 23 MET A CG 1 ATOM 45 S SD . MET A 1 22 ? 49.432 36.869 16.552 1.00 63.04 ? 23 MET A SD 1 ATOM 46 C CE . MET A 1 22 ? 50.857 37.381 15.560 1.00 60.83 ? 23 MET A CE 1 ATOM 47 N N . SER A 1 23 ? 47.338 40.729 19.520 1.00 43.35 ? 24 SER A N 1 ATOM 48 C CA . SER A 1 23 ? 45.924 40.884 19.877 1.00 41.81 ? 24 SER A CA 1 ATOM 49 C C . SER A 1 23 ? 45.088 40.415 18.713 1.00 46.16 ? 24 SER A C 1 ATOM 50 O O . SER A 1 23 ? 45.350 40.814 17.587 1.00 47.63 ? 24 SER A O 1 ATOM 51 C CB . SER A 1 23 ? 45.598 42.330 20.209 1.00 42.40 ? 24 SER A CB 1 ATOM 52 O OG . SER A 1 23 ? 46.174 42.645 21.462 1.00 55.07 ? 24 SER A OG 1 ATOM 53 N N . VAL A 1 24 ? 44.158 39.494 18.948 1.00 42.01 ? 25 VAL A N 1 ATOM 54 C CA . VAL A 1 24 ? 43.285 38.995 17.888 1.00 41.38 ? 25 VAL A CA 1 ATOM 55 C C . VAL A 1 24 ? 41.861 39.026 18.394 1.00 44.20 ? 25 VAL A C 1 ATOM 56 O O . VAL A 1 24 ? 41.582 38.745 19.562 1.00 44.06 ? 25 VAL A O 1 ATOM 57 C CB . VAL A 1 24 ? 43.684 37.617 17.263 1.00 46.30 ? 25 VAL A CB 1 ATOM 58 C CG1 . VAL A 1 24 ? 42.773 37.244 16.060 1.00 46.14 ? 25 VAL A CG1 1 ATOM 59 C CG2 . VAL A 1 24 ? 45.153 37.608 16.825 1.00 46.05 ? 25 VAL A CG2 1 ATOM 60 N N . GLN A 1 25 ? 40.963 39.402 17.503 1.00 40.07 ? 26 GLN A N 1 ATOM 61 C CA . GLN A 1 25 ? 39.553 39.536 17.765 1.00 39.37 ? 26 GLN A CA 1 ATOM 62 C C . GLN A 1 25 ? 38.827 38.201 17.641 1.00 43.05 ? 26 GLN A C 1 ATOM 63 O O . GLN A 1 25 ? 39.178 37.400 16.775 1.00 42.39 ? 26 GLN A O 1 ATOM 64 C CB . GLN A 1 25 ? 39.014 40.528 16.752 1.00 40.82 ? 26 GLN A CB 1 ATOM 65 C CG . GLN A 1 25 ? 37.811 41.278 17.234 1.00 62.54 ? 26 GLN A CG 1 ATOM 66 C CD . GLN A 1 25 ? 37.376 42.294 16.210 1.00 63.27 ? 26 GLN A CD 1 ATOM 67 O OE1 . GLN A 1 25 ? 38.100 43.254 15.900 1.00 52.98 ? 26 GLN A OE1 1 ATOM 68 N NE2 . GLN A 1 25 ? 36.178 42.106 15.679 1.00 49.60 ? 26 GLN A NE2 1 ATOM 69 N N . MET A 1 26 ? 37.765 37.991 18.469 1.00 41.40 ? 27 MET A N 1 ATOM 70 C CA . MET A 1 26 ? 36.895 36.793 18.476 1.00 42.81 ? 27 MET A CA 1 ATOM 71 C C . MET A 1 26 ? 36.434 36.490 17.088 1.00 48.43 ? 27 MET A C 1 ATOM 72 O O . MET A 1 26 ? 36.027 37.416 16.390 1.00 49.37 ? 27 MET A O 1 ATOM 73 C CB . MET A 1 26 ? 35.593 37.053 19.249 1.00 45.88 ? 27 MET A CB 1 ATOM 74 C CG . MET A 1 26 ? 35.717 37.019 20.723 1.00 51.04 ? 27 MET A CG 1 ATOM 75 S SD . MET A 1 26 ? 35.952 35.372 21.406 1.00 56.72 ? 27 MET A SD 1 ATOM 76 C CE . MET A 1 26 ? 34.443 34.580 21.004 1.00 52.79 ? 27 MET A CE 1 ATOM 77 N N . ASP A 1 27 ? 36.445 35.203 16.699 1.00 45.62 ? 28 ASP A N 1 ATOM 78 C CA . ASP A 1 27 ? 35.960 34.663 15.418 1.00 45.86 ? 28 ASP A CA 1 ATOM 79 C C . ASP A 1 27 ? 36.839 34.887 14.211 1.00 50.99 ? 28 ASP A C 1 ATOM 80 O O . ASP A 1 27 ? 36.564 34.335 13.150 1.00 52.73 ? 28 ASP A O 1 ATOM 81 C CB . ASP A 1 27 ? 34.488 35.049 15.128 1.00 48.65 ? 28 ASP A CB 1 ATOM 82 C CG . ASP A 1 27 ? 33.531 34.793 16.288 1.00 66.66 ? 28 ASP A CG 1 ATOM 83 O OD1 . ASP A 1 27 ? 33.569 33.680 16.861 1.00 68.32 ? 28 ASP A OD1 1 ATOM 84 O OD2 . ASP A 1 27 ? 32.783 35.723 16.656 1.00 73.81 ? 28 ASP A OD2 1 ATOM 85 N N . LYS A 1 28 ? 37.900 35.666 14.352 1.00 46.96 ? 29 LYS A N 1 ATOM 86 C CA . LYS A 1 28 ? 38.828 35.918 13.257 1.00 45.73 ? 29 LYS A CA 1 ATOM 87 C C . LYS A 1 28 ? 39.870 34.802 13.216 1.00 47.51 ? 29 LYS A C 1 ATOM 88 O O . LYS A 1 28 ? 39.977 34.010 14.163 1.00 46.94 ? 29 LYS A O 1 ATOM 89 C CB . LYS A 1 28 ? 39.507 37.292 13.431 1.00 48.29 ? 29 LYS A CB 1 ATOM 90 C CG . LYS A 1 28 ? 38.567 38.473 13.584 1.00 60.49 ? 29 LYS A CG 1 ATOM 91 C CD . LYS A 1 28 ? 37.800 38.784 12.318 1.00 78.52 ? 29 LYS A CD 1 ATOM 92 C CE . LYS A 1 28 ? 37.032 40.082 12.400 1.00 98.17 ? 29 LYS A CE 1 ATOM 93 N NZ . LYS A 1 28 ? 36.537 40.502 11.063 1.00 111.34 ? 29 LYS A NZ 1 ATOM 94 N N . LYS A 1 29 ? 40.606 34.712 12.101 1.00 42.52 ? 30 LYS A N 1 ATOM 95 C CA . LYS A 1 29 ? 41.673 33.739 11.912 1.00 41.21 ? 30 LYS A CA 1 ATOM 96 C C . LYS A 1 29 ? 42.984 34.359 12.429 1.00 45.00 ? 30 LYS A C 1 ATOM 97 O O . LYS A 1 29 ? 43.203 35.565 12.279 1.00 46.07 ? 30 LYS A O 1 ATOM 98 C CB . LYS A 1 29 ? 41.769 33.362 10.432 1.00 41.84 ? 30 LYS A CB 1 ATOM 99 C CG . LYS A 1 29 ? 42.894 32.406 10.082 1.00 49.42 ? 30 LYS A CG 1 ATOM 100 C CD . LYS A 1 29 ? 42.839 31.939 8.626 1.00 50.27 ? 30 LYS A CD 1 ATOM 101 C CE . LYS A 1 29 ? 43.872 32.605 7.753 1.00 56.55 ? 30 LYS A CE 1 ATOM 102 N NZ . LYS A 1 29 ? 44.210 31.757 6.579 1.00 74.20 ? 30 LYS A NZ 1 ATOM 103 N N . ALA A 1 30 ? 43.814 33.572 13.110 1.00 40.11 ? 31 ALA A N 1 ATOM 104 C CA . ALA A 1 30 ? 45.097 34.103 13.584 1.00 38.38 ? 31 ALA A CA 1 ATOM 105 C C . ALA A 1 30 ? 46.199 33.232 13.021 1.00 39.56 ? 31 ALA A C 1 ATOM 106 O O . ALA A 1 30 ? 46.008 32.030 12.881 1.00 38.59 ? 31 ALA A O 1 ATOM 107 C CB . ALA A 1 30 ? 45.146 34.118 15.095 1.00 39.33 ? 31 ALA A CB 1 ATOM 108 N N . LEU A 1 31 ? 47.319 33.849 12.643 1.00 34.91 ? 32 LEU A N 1 ATOM 109 C CA . LEU A 1 31 ? 48.467 33.179 12.078 1.00 33.94 ? 32 LEU A CA 1 ATOM 110 C C . LEU A 1 31 ? 49.699 33.593 12.838 1.00 39.65 ? 32 LEU A C 1 ATOM 111 O O . LEU A 1 31 ? 49.971 34.779 12.989 1.00 39.09 ? 32 LEU A O 1 ATOM 112 C CB . LEU A 1 31 ? 48.610 33.495 10.600 1.00 33.94 ? 32 LEU A CB 1 ATOM 113 C CG . LEU A 1 31 ? 47.559 32.866 9.680 1.00 38.07 ? 32 LEU A CG 1 ATOM 114 C CD1 . LEU A 1 31 ? 47.619 33.511 8.308 1.00 38.45 ? 32 LEU A CD1 1 ATOM 115 C CD2 . LEU A 1 31 ? 47.756 31.370 9.554 1.00 37.58 ? 32 LEU A CD2 1 ATOM 116 N N . LEU A 1 32 ? 50.409 32.601 13.387 1.00 37.72 ? 33 LEU A N 1 ATOM 117 C CA . LEU A 1 32 ? 51.587 32.829 14.224 1.00 37.17 ? 33 LEU A CA 1 ATOM 118 C C . LEU A 1 32 ? 52.760 32.268 13.487 1.00 41.86 ? 33 LEU A C 1 ATOM 119 O O . LEU A 1 32 ? 52.844 31.072 13.251 1.00 41.60 ? 33 LEU A O 1 ATOM 120 C CB . LEU A 1 32 ? 51.408 32.183 15.614 1.00 36.89 ? 33 LEU A CB 1 ATOM 121 C CG . LEU A 1 32 ? 50.498 32.901 16.611 1.00 42.29 ? 33 LEU A CG 1 ATOM 122 C CD1 . LEU A 1 32 ? 49.025 32.802 16.241 1.00 42.79 ? 33 LEU A CD1 1 ATOM 123 C CD2 . LEU A 1 32 ? 50.597 32.237 17.938 1.00 44.93 ? 33 LEU A CD2 1 ATOM 124 N N . CYS A 1 33 ? 53.619 33.149 13.037 1.00 42.14 ? 34 CYS A N 1 ATOM 125 C CA . CYS A 1 33 ? 54.774 32.775 12.246 1.00 44.11 ? 34 CYS A CA 1 ATOM 126 C C . CYS A 1 33 ? 55.917 32.335 13.142 1.00 44.58 ? 34 CYS A C 1 ATOM 127 O O . CYS A 1 33 ? 56.343 33.085 14.026 1.00 43.22 ? 34 CYS A O 1 ATOM 128 C CB . CYS A 1 33 ? 55.190 33.926 11.337 1.00 46.18 ? 34 CYS A CB 1 ATOM 129 S SG . CYS A 1 33 ? 56.524 33.505 10.204 1.00 52.07 ? 34 CYS A SG 1 ATOM 130 N N . CYS A 1 34 ? 56.446 31.156 12.897 1.00 38.64 ? 35 CYS A N 1 ATOM 131 C CA . CYS A 1 34 ? 57.569 30.720 13.712 1.00 38.76 ? 35 CYS A CA 1 ATOM 132 C C . CYS A 1 34 ? 58.880 31.427 13.249 1.00 41.94 ? 35 CYS A C 1 ATOM 133 O O . CYS A 1 34 ? 59.583 32.052 14.052 1.00 41.84 ? 35 CYS A O 1 ATOM 134 C CB . CYS A 1 34 ? 57.683 29.203 13.688 1.00 39.62 ? 35 CYS A CB 1 ATOM 135 S SG . CYS A 1 34 ? 58.958 28.581 14.792 1.00 44.23 ? 35 CYS A SG 1 ATOM 136 N N . PHE A 1 35 ? 59.139 31.403 11.924 1.00 34.72 ? 36 PHE A N 1 ATOM 137 C CA . PHE A 1 35 ? 60.245 32.083 11.241 1.00 32.36 ? 36 PHE A CA 1 ATOM 138 C C . PHE A 1 35 ? 59.918 31.978 9.767 1.00 38.17 ? 36 PHE A C 1 ATOM 139 O O . PHE A 1 35 ? 59.127 31.119 9.381 1.00 38.05 ? 36 PHE A O 1 ATOM 140 C CB . PHE A 1 35 ? 61.642 31.446 11.540 1.00 32.19 ? 36 PHE A CB 1 ATOM 141 C CG . PHE A 1 35 ? 61.819 30.014 11.106 1.00 31.74 ? 36 PHE A CG 1 ATOM 142 C CD1 . PHE A 1 35 ? 62.011 29.692 9.755 1.00 31.56 ? 36 PHE A CD1 1 ATOM 143 C CD2 . PHE A 1 35 ? 61.792 28.979 12.038 1.00 32.63 ? 36 PHE A CD2 1 ATOM 144 C CE1 . PHE A 1 35 ? 62.130 28.362 9.339 1.00 31.77 ? 36 PHE A CE1 1 ATOM 145 C CE2 . PHE A 1 35 ? 61.955 27.641 11.625 1.00 35.81 ? 36 PHE A CE2 1 ATOM 146 C CZ . PHE A 1 35 ? 62.117 27.343 10.275 1.00 32.90 ? 36 PHE A CZ 1 ATOM 147 N N . SER A 1 36 ? 60.539 32.814 8.939 1.00 35.97 ? 37 SER A N 1 ATOM 148 C CA . SER A 1 36 ? 60.368 32.735 7.502 1.00 36.11 ? 37 SER A CA 1 ATOM 149 C C . SER A 1 36 ? 61.709 32.895 6.861 1.00 41.10 ? 37 SER A C 1 ATOM 150 O O . SER A 1 36 ? 62.152 34.014 6.664 1.00 45.19 ? 37 SER A O 1 ATOM 151 C CB . SER A 1 36 ? 59.376 33.767 6.985 1.00 37.95 ? 37 SER A CB 1 ATOM 152 O OG . SER A 1 36 ? 59.043 33.414 5.651 1.00 47.10 ? 37 SER A OG 1 ATOM 153 N N . SER A 1 37 ? 62.395 31.786 6.606 1.00 35.34 ? 38 SER A N 1 ATOM 154 C CA . SER A 1 37 ? 63.728 31.806 6.036 1.00 35.65 ? 38 SER A CA 1 ATOM 155 C C . SER A 1 37 ? 64.063 30.481 5.369 1.00 42.14 ? 38 SER A C 1 ATOM 156 O O . SER A 1 37 ? 63.940 29.438 5.999 1.00 43.98 ? 38 SER A O 1 ATOM 157 C CB . SER A 1 37 ? 64.776 32.094 7.111 1.00 36.84 ? 38 SER A CB 1 ATOM 158 O OG . SER A 1 37 ? 66.082 32.090 6.556 1.00 38.95 ? 38 SER A OG 1 ATOM 159 N N . PRO A 1 38 ? 64.605 30.496 4.148 1.00 39.03 ? 39 PRO A N 1 ATOM 160 C CA . PRO A 1 38 ? 65.032 29.224 3.537 1.00 38.65 ? 39 PRO A CA 1 ATOM 161 C C . PRO A 1 38 ? 66.342 28.691 4.149 1.00 40.76 ? 39 PRO A C 1 ATOM 162 O O . PRO A 1 38 ? 66.748 27.571 3.860 1.00 41.85 ? 39 PRO A O 1 ATOM 163 C CB . PRO A 1 38 ? 65.227 29.607 2.059 1.00 39.84 ? 39 PRO A CB 1 ATOM 164 C CG . PRO A 1 38 ? 65.631 31.052 2.097 1.00 43.45 ? 39 PRO A CG 1 ATOM 165 C CD . PRO A 1 38 ? 64.854 31.650 3.250 1.00 39.57 ? 39 PRO A CD 1 ATOM 166 N N . LEU A 1 39 ? 67.013 29.502 4.974 1.00 34.21 ? 40 LEU A N 1 ATOM 167 C CA . LEU A 1 39 ? 68.321 29.176 5.544 1.00 31.26 ? 40 LEU A CA 1 ATOM 168 C C . LEU A 1 39 ? 68.289 28.420 6.868 1.00 35.49 ? 40 LEU A C 1 ATOM 169 O O . LEU A 1 39 ? 69.334 27.902 7.277 1.00 37.72 ? 40 LEU A O 1 ATOM 170 C CB . LEU A 1 39 ? 69.166 30.461 5.692 1.00 29.86 ? 40 LEU A CB 1 ATOM 171 C CG . LEU A 1 39 ? 69.300 31.391 4.454 1.00 31.25 ? 40 LEU A CG 1 ATOM 172 C CD1 . LEU A 1 39 ? 70.260 32.497 4.730 1.00 29.06 ? 40 LEU A CD1 1 ATOM 173 C CD2 . LEU A 1 39 ? 69.762 30.623 3.228 1.00 30.14 ? 40 LEU A CD2 1 ATOM 174 N N . ILE A 1 40 ? 67.145 28.396 7.565 1.00 29.87 ? 41 ILE A N 1 ATOM 175 C CA . ILE A 1 40 ? 67.082 27.720 8.865 1.00 30.50 ? 41 ILE A CA 1 ATOM 176 C C . ILE A 1 40 ? 66.862 26.214 8.641 1.00 37.36 ? 41 ILE A C 1 ATOM 177 O O . ILE A 1 40 ? 65.828 25.821 8.081 1.00 36.56 ? 41 ILE A O 1 ATOM 178 C CB . ILE A 1 40 ? 66.081 28.412 9.856 1.00 32.22 ? 41 ILE A CB 1 ATOM 179 C CG1 . ILE A 1 40 ? 66.591 29.821 10.217 1.00 31.91 ? 41 ILE A CG1 1 ATOM 180 C CG2 . ILE A 1 40 ? 65.873 27.604 11.124 1.00 31.19 ? 41 ILE A CG2 1 ATOM 181 C CD1 . ILE A 1 40 ? 65.525 30.814 10.629 1.00 30.80 ? 41 ILE A CD1 1 ATOM 182 N N . ASN A 1 41 ? 67.874 25.387 9.013 1.00 35.55 ? 42 ASN A N 1 ATOM 183 C CA . ASN A 1 41 ? 67.835 23.911 8.882 1.00 36.34 ? 42 ASN A CA 1 ATOM 184 C C . ASN A 1 41 ? 67.016 23.270 10.022 1.00 39.65 ? 42 ASN A C 1 ATOM 185 O O . ASN A 1 41 ? 67.611 22.671 10.911 1.00 39.29 ? 42 ASN A O 1 ATOM 186 C CB . ASN A 1 41 ? 69.269 23.331 8.919 1.00 41.90 ? 42 ASN A CB 1 ATOM 187 C CG . ASN A 1 41 ? 70.149 23.631 7.711 1.00 70.94 ? 42 ASN A CG 1 ATOM 188 O OD1 . ASN A 1 41 ? 69.916 23.136 6.587 1.00 59.42 ? 42 ASN A OD1 1 ATOM 189 N ND2 . ASN A 1 41 ? 71.252 24.351 7.951 1.00 57.42 ? 42 ASN A ND2 1 ATOM 190 N N . ALA A 1 42 ? 65.689 23.425 10.035 1.00 35.47 ? 43 ALA A N 1 ATOM 191 C CA . ALA A 1 42 ? 64.896 22.866 11.126 1.00 36.16 ? 43 ALA A CA 1 ATOM 192 C C . ALA A 1 42 ? 64.676 21.380 10.930 1.00 41.21 ? 43 ALA A C 1 ATOM 193 O O . ALA A 1 42 ? 64.219 20.962 9.857 1.00 41.49 ? 43 ALA A O 1 ATOM 194 C CB . ALA A 1 42 ? 63.560 23.584 11.244 1.00 36.68 ? 43 ALA A CB 1 ATOM 195 N N . VAL A 1 43 ? 65.021 20.580 11.953 1.00 36.62 ? 44 VAL A N 1 ATOM 196 C CA . VAL A 1 43 ? 64.801 19.149 11.881 1.00 37.05 ? 44 VAL A CA 1 ATOM 197 C C . VAL A 1 43 ? 63.433 18.819 12.516 1.00 41.28 ? 44 VAL A C 1 ATOM 198 O O . VAL A 1 43 ? 62.631 18.091 11.924 1.00 43.03 ? 44 VAL A O 1 ATOM 199 C CB . VAL A 1 43 ? 66.020 18.281 12.309 1.00 42.05 ? 44 VAL A CB 1 ATOM 200 C CG1 . VAL A 1 43 ? 67.316 18.821 11.706 1.00 41.38 ? 44 VAL A CG1 1 ATOM 201 C CG2 . VAL A 1 43 ? 66.167 18.189 13.807 1.00 42.76 ? 44 VAL A CG2 1 ATOM 202 N N . LEU A 1 44 ? 63.151 19.445 13.675 1.00 35.72 ? 45 LEU A N 1 ATOM 203 C CA A LEU A 1 44 ? 61.880 19.294 14.370 0.50 35.93 ? 45 LEU A CA 1 ATOM 204 C CA B LEU A 1 44 ? 61.912 19.297 14.440 0.50 34.50 ? 45 LEU A CA 1 ATOM 205 C C . LEU A 1 44 ? 61.368 20.675 14.818 1.00 39.82 ? 45 LEU A C 1 ATOM 206 O O . LEU A 1 44 ? 62.128 21.509 15.320 1.00 40.31 ? 45 LEU A O 1 ATOM 207 C CB A LEU A 1 44 ? 61.991 18.271 15.546 0.50 36.31 ? 45 LEU A CB 1 ATOM 208 C CB B LEU A 1 44 ? 62.148 18.510 15.764 0.50 33.65 ? 45 LEU A CB 1 ATOM 209 C CG A LEU A 1 44 ? 60.744 18.000 16.438 0.50 41.26 ? 45 LEU A CG 1 ATOM 210 C CG B LEU A 1 44 ? 63.011 17.254 15.770 0.50 35.73 ? 45 LEU A CG 1 ATOM 211 C CD1 A LEU A 1 44 ? 59.768 16.992 15.800 0.50 40.70 ? 45 LEU A CD1 1 ATOM 212 C CD1 B LEU A 1 44 ? 63.609 17.028 17.138 0.50 34.97 ? 45 LEU A CD1 1 ATOM 213 C CD2 A LEU A 1 44 ? 61.161 17.491 17.803 0.50 45.71 ? 45 LEU A CD2 1 ATOM 214 C CD2 B LEU A 1 44 ? 62.225 16.061 15.355 0.50 34.52 ? 45 LEU A CD2 1 ATOM 215 N N . ILE A 1 45 ? 60.055 20.905 14.611 1.00 36.85 ? 46 ILE A N 1 ATOM 216 C CA . ILE A 1 45 ? 59.357 22.135 14.985 1.00 36.25 ? 46 ILE A CA 1 ATOM 217 C C . ILE A 1 45 ? 58.186 21.757 15.878 1.00 37.21 ? 46 ILE A C 1 ATOM 218 O O . ILE A 1 45 ? 57.350 20.945 15.496 1.00 36.98 ? 46 ILE A O 1 ATOM 219 C CB . ILE A 1 45 ? 58.933 23.014 13.767 1.00 39.69 ? 46 ILE A CB 1 ATOM 220 C CG1 . ILE A 1 45 ? 60.161 23.468 12.955 1.00 40.11 ? 46 ILE A CG1 1 ATOM 221 C CG2 . ILE A 1 45 ? 58.133 24.234 14.242 1.00 39.15 ? 46 ILE A CG2 1 ATOM 222 C CD1 . ILE A 1 45 ? 59.841 23.976 11.611 1.00 45.39 ? 46 ILE A CD1 1 ATOM 223 N N . THR A 1 46 ? 58.134 22.335 17.070 1.00 32.54 ? 47 THR A N 1 ATOM 224 C CA . THR A 1 46 ? 57.080 22.034 18.035 1.00 31.83 ? 47 THR A CA 1 ATOM 225 C C . THR A 1 46 ? 56.455 23.322 18.545 1.00 35.65 ? 47 THR A C 1 ATOM 226 O O . THR A 1 46 ? 57.177 24.207 19.005 1.00 36.29 ? 47 THR A O 1 ATOM 227 C CB . THR A 1 46 ? 57.704 21.238 19.222 1.00 37.30 ? 47 THR A CB 1 ATOM 228 O OG1 . THR A 1 46 ? 58.277 20.020 18.746 1.00 45.36 ? 47 THR A OG1 1 ATOM 229 C CG2 . THR A 1 46 ? 56.736 20.929 20.310 1.00 31.21 ? 47 THR A CG2 1 ATOM 230 N N . TRP A 1 47 ? 55.119 23.397 18.556 1.00 30.96 ? 48 TRP A N 1 ATOM 231 C CA . TRP A 1 47 ? 54.422 24.513 19.194 1.00 30.35 ? 48 TRP A CA 1 ATOM 232 C C . TRP A 1 47 ? 53.884 24.020 20.528 1.00 33.56 ? 48 TRP A C 1 ATOM 233 O O . TRP A 1 47 ? 53.225 22.990 20.575 1.00 32.48 ? 48 TRP A O 1 ATOM 234 C CB . TRP A 1 47 ? 53.257 25.036 18.348 1.00 29.30 ? 48 TRP A CB 1 ATOM 235 C CG . TRP A 1 47 ? 53.650 25.892 17.171 1.00 30.94 ? 48 TRP A CG 1 ATOM 236 C CD1 . TRP A 1 47 ? 53.805 25.487 15.875 1.00 33.48 ? 48 TRP A CD1 1 ATOM 237 C CD2 . TRP A 1 47 ? 53.871 27.318 17.175 1.00 30.70 ? 48 TRP A CD2 1 ATOM 238 N NE1 . TRP A 1 47 ? 54.092 26.571 15.070 1.00 32.10 ? 48 TRP A NE1 1 ATOM 239 C CE2 . TRP A 1 47 ? 54.159 27.703 15.845 1.00 33.95 ? 48 TRP A CE2 1 ATOM 240 C CE3 . TRP A 1 47 ? 53.811 28.312 18.167 1.00 31.30 ? 48 TRP A CE3 1 ATOM 241 C CZ2 . TRP A 1 47 ? 54.382 29.040 15.486 1.00 33.01 ? 48 TRP A CZ2 1 ATOM 242 C CZ3 . TRP A 1 47 ? 54.081 29.626 17.815 1.00 32.51 ? 48 TRP A CZ3 1 ATOM 243 C CH2 . TRP A 1 47 ? 54.368 29.979 16.493 1.00 32.84 ? 48 TRP A CH2 1 ATOM 244 N N . ILE A 1 48 ? 54.176 24.736 21.612 1.00 31.49 ? 49 ILE A N 1 ATOM 245 C CA . ILE A 1 48 ? 53.649 24.450 22.952 1.00 29.98 ? 49 ILE A CA 1 ATOM 246 C C . ILE A 1 48 ? 52.702 25.588 23.275 1.00 32.68 ? 49 ILE A C 1 ATOM 247 O O . ILE A 1 48 ? 53.094 26.750 23.224 1.00 32.35 ? 49 ILE A O 1 ATOM 248 C CB . ILE A 1 48 ? 54.760 24.258 24.026 1.00 32.55 ? 49 ILE A CB 1 ATOM 249 C CG1 . ILE A 1 48 ? 55.672 23.068 23.679 1.00 32.53 ? 49 ILE A CG1 1 ATOM 250 C CG2 . ILE A 1 48 ? 54.151 24.056 25.414 1.00 32.58 ? 49 ILE A CG2 1 ATOM 251 C CD1 . ILE A 1 48 ? 56.949 23.474 23.240 1.00 43.22 ? 49 ILE A CD1 1 ATOM 252 N N . ILE A 1 49 ? 51.438 25.252 23.556 1.00 30.61 ? 50 ILE A N 1 ATOM 253 C CA . ILE A 1 49 ? 50.374 26.215 23.824 1.00 31.09 ? 50 ILE A CA 1 ATOM 254 C C . ILE A 1 49 ? 49.919 26.111 25.256 1.00 38.48 ? 50 ILE A C 1 ATOM 255 O O . ILE A 1 49 ? 49.425 25.069 25.649 1.00 40.48 ? 50 ILE A O 1 ATOM 256 C CB . ILE A 1 49 ? 49.222 26.013 22.798 1.00 34.12 ? 50 ILE A CB 1 ATOM 257 C CG1 . ILE A 1 49 ? 49.759 26.129 21.331 1.00 32.39 ? 50 ILE A CG1 1 ATOM 258 C CG2 . ILE A 1 49 ? 48.102 26.992 23.070 1.00 33.67 ? 50 ILE A CG2 1 ATOM 259 C CD1 . ILE A 1 49 ? 49.352 25.043 20.449 1.00 34.67 ? 50 ILE A CD1 1 ATOM 260 N N . LYS A 1 50 ? 50.103 27.179 26.032 1.00 35.95 ? 51 LYS A N 1 ATOM 261 C CA . LYS A 1 50 ? 49.815 27.266 27.461 1.00 35.72 ? 51 LYS A CA 1 ATOM 262 C C . LYS A 1 50 ? 48.786 28.326 27.800 1.00 43.56 ? 51 LYS A C 1 ATOM 263 O O . LYS A 1 50 ? 48.830 29.437 27.291 1.00 40.46 ? 51 LYS A O 1 ATOM 264 C CB . LYS A 1 50 ? 51.094 27.509 28.272 1.00 36.91 ? 51 LYS A CB 1 ATOM 265 C CG . LYS A 1 50 ? 52.099 26.379 28.177 1.00 55.78 ? 51 LYS A CG 1 ATOM 266 C CD . LYS A 1 50 ? 53.247 26.576 29.146 1.00 69.71 ? 51 LYS A CD 1 ATOM 267 C CE . LYS A 1 50 ? 54.523 25.900 28.690 1.00 87.31 ? 51 LYS A CE 1 ATOM 268 N NZ . LYS A 1 50 ? 55.244 26.665 27.619 1.00 96.13 ? 51 LYS A NZ 1 ATOM 269 N N . HIS A 1 51 ? 47.880 27.976 28.716 1.00 47.04 ? 52 HIS A N 1 ATOM 270 C CA . HIS A 1 51 ? 46.771 28.825 29.158 1.00 48.45 ? 52 HIS A CA 1 ATOM 271 C C . HIS A 1 51 ? 46.811 29.012 30.663 1.00 55.00 ? 52 HIS A C 1 ATOM 272 O O . HIS A 1 51 ? 47.506 28.269 31.359 1.00 53.94 ? 52 HIS A O 1 ATOM 273 C CB . HIS A 1 51 ? 45.445 28.221 28.697 1.00 49.77 ? 52 HIS A CB 1 ATOM 274 C CG . HIS A 1 51 ? 45.469 27.783 27.250 1.00 54.30 ? 52 HIS A CG 1 ATOM 275 N ND1 . HIS A 1 51 ? 45.445 28.720 26.193 1.00 56.37 ? 52 HIS A ND1 1 ATOM 276 C CD2 . HIS A 1 51 ? 45.549 26.534 26.720 1.00 56.35 ? 52 HIS A CD2 1 ATOM 277 C CE1 . HIS A 1 51 ? 45.448 28.003 25.073 1.00 55.85 ? 52 HIS A CE1 1 ATOM 278 N NE2 . HIS A 1 51 ? 45.504 26.683 25.329 1.00 56.24 ? 52 HIS A NE2 1 ATOM 279 N N . ARG A 1 52 ? 46.104 30.029 31.163 1.00 55.52 ? 53 ARG A N 1 ATOM 280 C CA . ARG A 1 52 ? 46.079 30.341 32.585 1.00 56.82 ? 53 ARG A CA 1 ATOM 281 C C . ARG A 1 52 ? 45.432 29.208 33.365 1.00 63.03 ? 53 ARG A C 1 ATOM 282 O O . ARG A 1 52 ? 45.993 28.767 34.372 1.00 62.82 ? 53 ARG A O 1 ATOM 283 C CB . ARG A 1 52 ? 45.374 31.681 32.844 1.00 60.02 ? 53 ARG A CB 1 ATOM 284 C CG . ARG A 1 52 ? 45.935 32.437 34.039 1.00 77.09 ? 53 ARG A CG 1 ATOM 285 C CD . ARG A 1 52 ? 45.175 33.717 34.317 1.00 94.40 ? 53 ARG A CD 1 ATOM 286 N NE . ARG A 1 52 ? 44.940 33.874 35.753 1.00 108.19 ? 53 ARG A NE 1 ATOM 287 C CZ . ARG A 1 52 ? 44.124 34.774 36.291 1.00 123.63 ? 53 ARG A CZ 1 ATOM 288 N NH1 . ARG A 1 52 ? 43.400 35.573 35.517 1.00 111.12 ? 53 ARG A NH1 1 ATOM 289 N NH2 . ARG A 1 52 ? 43.990 34.850 37.608 1.00 112.47 ? 53 ARG A NH2 1 ATOM 290 N N . HIS A 1 53 ? 44.299 28.684 32.860 1.00 61.58 ? 54 HIS A N 1 ATOM 291 C CA . HIS A 1 53 ? 43.579 27.605 33.536 1.00 61.96 ? 54 HIS A CA 1 ATOM 292 C C . HIS A 1 53 ? 43.451 26.348 32.729 1.00 64.54 ? 54 HIS A C 1 ATOM 293 O O . HIS A 1 53 ? 43.655 25.272 33.279 1.00 66.63 ? 54 HIS A O 1 ATOM 294 C CB . HIS A 1 53 ? 42.217 28.086 34.086 1.00 63.31 ? 54 HIS A CB 1 ATOM 295 C CG . HIS A 1 53 ? 42.352 29.283 34.977 1.00 67.04 ? 54 HIS A CG 1 ATOM 296 N ND1 . HIS A 1 53 ? 43.112 29.234 36.140 1.00 69.17 ? 54 HIS A ND1 1 ATOM 297 C CD2 . HIS A 1 53 ? 41.909 30.549 34.801 1.00 69.11 ? 54 HIS A CD2 1 ATOM 298 C CE1 . HIS A 1 53 ? 43.084 30.462 36.645 1.00 68.60 ? 54 HIS A CE1 1 ATOM 299 N NE2 . HIS A 1 53 ? 42.367 31.288 35.879 1.00 68.96 ? 54 HIS A NE2 1 ATOM 300 N N . LEU A 1 54 ? 43.131 26.469 31.440 1.00 58.27 ? 55 LEU A N 1 ATOM 301 C CA . LEU A 1 54 ? 42.961 25.369 30.490 1.00 57.40 ? 55 LEU A CA 1 ATOM 302 C C . LEU A 1 54 ? 44.267 24.546 30.351 1.00 58.60 ? 55 LEU A C 1 ATOM 303 O O . LEU A 1 54 ? 45.352 25.127 30.504 1.00 57.51 ? 55 LEU A O 1 ATOM 304 C CB . LEU A 1 54 ? 42.530 25.986 29.136 1.00 58.13 ? 55 LEU A CB 1 ATOM 305 C CG . LEU A 1 54 ? 42.049 25.081 27.980 1.00 64.12 ? 55 LEU A CG 1 ATOM 306 C CD1 . LEU A 1 54 ? 40.678 24.491 28.270 1.00 65.09 ? 55 LEU A CD1 1 ATOM 307 C CD2 . LEU A 1 54 ? 41.987 25.856 26.655 1.00 64.66 ? 55 LEU A CD2 1 ATOM 308 N N . PRO A 1 55 ? 44.203 23.198 30.133 1.00 53.69 ? 56 PRO A N 1 ATOM 309 C CA . PRO A 1 55 ? 45.450 22.428 29.998 1.00 53.08 ? 56 PRO A CA 1 ATOM 310 C C . PRO A 1 55 ? 46.192 22.714 28.692 1.00 54.09 ? 56 PRO A C 1 ATOM 311 O O . PRO A 1 55 ? 45.591 23.044 27.662 1.00 52.83 ? 56 PRO A O 1 ATOM 312 C CB . PRO A 1 55 ? 44.996 20.960 30.081 1.00 55.02 ? 56 PRO A CB 1 ATOM 313 C CG . PRO A 1 55 ? 43.574 20.961 29.718 1.00 58.67 ? 56 PRO A CG 1 ATOM 314 C CD . PRO A 1 55 ? 43.014 22.326 29.986 1.00 54.41 ? 56 PRO A CD 1 ATOM 315 N N . SER A 1 56 ? 47.512 22.585 28.760 1.00 49.07 ? 57 SER A N 1 ATOM 316 C CA . SER A 1 56 ? 48.393 22.824 27.637 1.00 47.91 ? 57 SER A CA 1 ATOM 317 C C . SER A 1 56 ? 48.236 21.782 26.526 1.00 49.91 ? 57 SER A C 1 ATOM 318 O O . SER A 1 56 ? 47.712 20.693 26.762 1.00 49.89 ? 57 SER A O 1 ATOM 319 C CB . SER A 1 56 ? 49.839 22.987 28.112 1.00 50.39 ? 57 SER A CB 1 ATOM 320 O OG . SER A 1 56 ? 50.572 21.780 28.119 1.00 64.05 ? 57 SER A OG 1 ATOM 321 N N . CYS A 1 57 ? 48.622 22.148 25.305 1.00 44.88 ? 58 CYS A N 1 ATOM 322 C CA . CYS A 1 57 ? 48.617 21.240 24.159 1.00 44.11 ? 58 CYS A CA 1 ATOM 323 C C . CYS A 1 57 ? 49.789 21.542 23.195 1.00 41.95 ? 58 CYS A C 1 ATOM 324 O O . CYS A 1 57 ? 50.483 22.543 23.360 1.00 38.22 ? 58 CYS A O 1 ATOM 325 C CB . CYS A 1 57 ? 47.255 21.126 23.470 1.00 46.12 ? 58 CYS A CB 1 ATOM 326 S SG . CYS A 1 57 ? 46.855 22.472 22.316 1.00 51.75 ? 58 CYS A SG 1 ATOM 327 N N . THR A 1 58 ? 50.068 20.630 22.265 1.00 38.11 ? 59 THR A N 1 ATOM 328 C CA . THR A 1 58 ? 51.248 20.677 21.412 1.00 36.28 ? 59 THR A CA 1 ATOM 329 C C . THR A 1 58 ? 50.926 20.202 20.015 1.00 38.51 ? 59 THR A C 1 ATOM 330 O O . THR A 1 58 ? 50.135 19.278 19.846 1.00 39.81 ? 59 THR A O 1 ATOM 331 C CB . THR A 1 58 ? 52.341 19.745 22.067 1.00 40.79 ? 59 THR A CB 1 ATOM 332 O OG1 . THR A 1 58 ? 52.742 20.280 23.325 1.00 47.63 ? 59 THR A OG1 1 ATOM 333 C CG2 . THR A 1 58 ? 53.588 19.588 21.246 1.00 42.05 ? 59 THR A CG2 1 ATOM 334 N N . ILE A 1 59 ? 51.551 20.828 19.017 1.00 33.25 ? 60 ILE A N 1 ATOM 335 C CA . ILE A 1 59 ? 51.548 20.399 17.619 1.00 32.90 ? 60 ILE A CA 1 ATOM 336 C C . ILE A 1 59 ? 53.037 20.317 17.263 1.00 36.32 ? 60 ILE A C 1 ATOM 337 O O . ILE A 1 59 ? 53.801 21.218 17.614 1.00 37.08 ? 60 ILE A O 1 ATOM 338 C CB . ILE A 1 59 ? 50.648 21.208 16.620 1.00 36.36 ? 60 ILE A CB 1 ATOM 339 C CG1 . ILE A 1 59 ? 51.102 22.675 16.438 1.00 37.03 ? 60 ILE A CG1 1 ATOM 340 C CG2 . ILE A 1 59 ? 49.174 21.137 17.021 1.00 38.07 ? 60 ILE A CG2 1 ATOM 341 C CD1 . ILE A 1 59 ? 50.469 23.427 15.264 1.00 42.00 ? 60 ILE A CD1 1 ATOM 342 N N . ALA A 1 60 ? 53.470 19.186 16.700 1.00 32.72 ? 61 ALA A N 1 ATOM 343 C CA . ALA A 1 60 ? 54.867 18.943 16.347 1.00 32.48 ? 61 ALA A CA 1 ATOM 344 C C . ALA A 1 60 ? 55.008 18.403 14.952 1.00 41.93 ? 61 ALA A C 1 ATOM 345 O O . ALA A 1 60 ? 54.123 17.675 14.481 1.00 45.23 ? 61 ALA A O 1 ATOM 346 C CB . ALA A 1 60 ? 55.494 17.977 17.337 1.00 32.61 ? 61 ALA A CB 1 ATOM 347 N N . TYR A 1 61 ? 56.108 18.769 14.274 1.00 37.61 ? 62 TYR A N 1 ATOM 348 C CA . TYR A 1 61 ? 56.370 18.324 12.918 1.00 38.04 ? 62 TYR A CA 1 ATOM 349 C C . TYR A 1 61 ? 57.807 17.919 12.792 1.00 44.52 ? 62 TYR A C 1 ATOM 350 O O . TYR A 1 61 ? 58.723 18.660 13.172 1.00 44.11 ? 62 TYR A O 1 ATOM 351 C CB . TYR A 1 61 ? 56.006 19.391 11.859 1.00 39.41 ? 62 TYR A CB 1 ATOM 352 C CG . TYR A 1 61 ? 55.800 18.810 10.477 1.00 44.07 ? 62 TYR A CG 1 ATOM 353 C CD1 . TYR A 1 61 ? 56.880 18.563 9.630 1.00 44.86 ? 62 TYR A CD1 1 ATOM 354 C CD2 . TYR A 1 61 ? 54.521 18.517 10.005 1.00 46.66 ? 62 TYR A CD2 1 ATOM 355 C CE1 . TYR A 1 61 ? 56.697 17.982 8.376 1.00 45.09 ? 62 TYR A CE1 1 ATOM 356 C CE2 . TYR A 1 61 ? 54.322 17.960 8.739 1.00 46.38 ? 62 TYR A CE2 1 ATOM 357 C CZ . TYR A 1 61 ? 55.413 17.680 7.934 1.00 55.52 ? 62 TYR A CZ 1 ATOM 358 O OH . TYR A 1 61 ? 55.199 17.121 6.687 1.00 61.78 ? 62 TYR A OH 1 ATOM 359 N N . ASN A 1 62 ? 57.991 16.713 12.268 1.00 43.03 ? 63 ASN A N 1 ATOM 360 C CA . ASN A 1 62 ? 59.312 16.180 12.017 1.00 44.23 ? 63 ASN A CA 1 ATOM 361 C C . ASN A 1 62 ? 59.608 16.439 10.557 1.00 49.91 ? 63 ASN A C 1 ATOM 362 O O . ASN A 1 62 ? 59.020 15.777 9.705 1.00 49.19 ? 63 ASN A O 1 ATOM 363 C CB . ASN A 1 62 ? 59.394 14.689 12.352 1.00 42.93 ? 63 ASN A CB 1 ATOM 364 C CG . ASN A 1 62 ? 60.814 14.224 12.330 1.00 52.06 ? 63 ASN A CG 1 ATOM 365 O OD1 . ASN A 1 62 ? 61.565 14.519 11.402 1.00 40.49 ? 63 ASN A OD1 1 ATOM 366 N ND2 . ASN A 1 62 ? 61.233 13.532 13.370 1.00 47.46 ? 63 ASN A ND2 1 ATOM 367 N N . LEU A 1 63 ? 60.481 17.426 10.261 1.00 48.28 ? 64 LEU A N 1 ATOM 368 C CA . LEU A 1 63 ? 60.793 17.781 8.869 1.00 49.44 ? 64 LEU A CA 1 ATOM 369 C C . LEU A 1 63 ? 61.702 16.749 8.193 1.00 57.56 ? 64 LEU A C 1 ATOM 370 O O . LEU A 1 63 ? 61.647 16.583 6.972 1.00 56.98 ? 64 LEU A O 1 ATOM 371 C CB . LEU A 1 63 ? 61.367 19.203 8.741 1.00 48.81 ? 64 LEU A CB 1 ATOM 372 C CG . LEU A 1 63 ? 60.378 20.350 8.909 1.00 51.40 ? 64 LEU A CG 1 ATOM 373 C CD1 . LEU A 1 63 ? 60.188 20.677 10.373 1.00 49.96 ? 64 LEU A CD1 1 ATOM 374 C CD2 . LEU A 1 63 ? 60.863 21.587 8.167 1.00 52.97 ? 64 LEU A CD2 1 ATOM 375 N N . ASP A 1 64 ? 62.511 16.044 8.993 1.00 57.45 ? 65 ASP A N 1 ATOM 376 C CA . ASP A 1 64 ? 63.375 14.994 8.501 1.00 58.87 ? 65 ASP A CA 1 ATOM 377 C C . ASP A 1 64 ? 62.525 13.782 8.007 1.00 63.05 ? 65 ASP A C 1 ATOM 378 O O . ASP A 1 64 ? 62.580 13.442 6.824 1.00 64.48 ? 65 ASP A O 1 ATOM 379 C CB . ASP A 1 64 ? 64.357 14.581 9.610 1.00 61.92 ? 65 ASP A CB 1 ATOM 380 C CG . ASP A 1 64 ? 65.467 13.649 9.146 1.00 82.87 ? 65 ASP A CG 1 ATOM 381 O OD1 . ASP A 1 64 ? 65.735 13.596 7.917 1.00 84.76 ? 65 ASP A OD1 1 ATOM 382 O OD2 . ASP A 1 64 ? 66.092 12.990 10.014 1.00 93.62 ? 65 ASP A OD2 1 ATOM 383 N N . LYS A 1 65 ? 61.700 13.189 8.904 1.00 56.82 ? 66 LYS A N 1 ATOM 384 C CA . LYS A 1 65 ? 60.856 12.020 8.644 1.00 54.35 ? 66 LYS A CA 1 ATOM 385 C C . LYS A 1 65 ? 59.507 12.337 8.009 1.00 56.30 ? 66 LYS A C 1 ATOM 386 O O . LYS A 1 65 ? 58.743 11.412 7.719 1.00 55.71 ? 66 LYS A O 1 ATOM 387 C CB . LYS A 1 65 ? 60.674 11.170 9.920 1.00 55.84 ? 66 LYS A CB 1 ATOM 388 C CG . LYS A 1 65 ? 61.953 10.867 10.711 1.00 69.63 ? 66 LYS A CG 1 ATOM 389 C CD . LYS A 1 65 ? 62.986 10.039 9.943 1.00 84.28 ? 66 LYS A CD 1 ATOM 390 C CE . LYS A 1 65 ? 64.350 10.096 10.578 1.00 100.91 ? 66 LYS A CE 1 ATOM 391 N NZ . LYS A 1 65 ? 65.394 9.504 9.697 1.00 110.35 ? 66 LYS A NZ 1 ATOM 392 N N . LYS A 1 66 ? 59.215 13.630 7.776 1.00 52.34 ? 67 LYS A N 1 ATOM 393 C CA . LYS A 1 66 ? 57.947 14.114 7.201 1.00 52.13 ? 67 LYS A CA 1 ATOM 394 C C . LYS A 1 66 ? 56.663 13.627 7.959 1.00 56.12 ? 67 LYS A C 1 ATOM 395 O O . LYS A 1 66 ? 55.607 13.423 7.363 1.00 56.25 ? 67 LYS A O 1 ATOM 396 C CB . LYS A 1 66 ? 57.892 13.927 5.664 1.00 54.75 ? 67 LYS A CB 1 ATOM 397 C CG . LYS A 1 66 ? 58.863 14.831 4.903 1.00 69.81 ? 67 LYS A CG 1 ATOM 398 C CD . LYS A 1 66 ? 58.570 14.883 3.412 1.00 85.91 ? 67 LYS A CD 1 ATOM 399 C CE . LYS A 1 66 ? 59.398 15.929 2.698 1.00 99.12 ? 67 LYS A CE 1 ATOM 400 N NZ . LYS A 1 66 ? 58.917 16.168 1.310 1.00 109.84 ? 67 LYS A NZ 1 ATOM 401 N N . THR A 1 67 ? 56.777 13.475 9.292 1.00 51.67 ? 68 THR A N 1 ATOM 402 C CA . THR A 1 67 ? 55.689 13.041 10.170 1.00 50.26 ? 68 THR A CA 1 ATOM 403 C C . THR A 1 67 ? 55.256 14.162 11.141 1.00 51.38 ? 68 THR A C 1 ATOM 404 O O . THR A 1 67 ? 56.017 15.095 11.407 1.00 51.82 ? 68 THR A O 1 ATOM 405 C CB . THR A 1 67 ? 56.076 11.752 10.898 1.00 59.87 ? 68 THR A CB 1 ATOM 406 O OG1 . THR A 1 67 ? 57.223 11.992 11.710 1.00 60.39 ? 68 THR A OG1 1 ATOM 407 C CG2 . THR A 1 67 ? 56.351 10.595 9.939 1.00 57.81 ? 68 THR A CG2 1 ATOM 408 N N . ASN A 1 68 ? 54.022 14.091 11.639 1.00 44.86 ? 69 ASN A N 1 ATOM 409 C CA . ASN A 1 68 ? 53.494 15.093 12.543 1.00 43.16 ? 69 ASN A CA 1 ATOM 410 C C . ASN A 1 68 ? 52.587 14.492 13.588 1.00 46.45 ? 69 ASN A C 1 ATOM 411 O O . ASN A 1 68 ? 52.015 13.430 13.364 1.00 46.78 ? 69 ASN A O 1 ATOM 412 C CB . ASN A 1 68 ? 52.773 16.192 11.777 1.00 41.21 ? 69 ASN A CB 1 ATOM 413 C CG . ASN A 1 68 ? 51.462 15.818 11.179 1.00 77.80 ? 69 ASN A CG 1 ATOM 414 O OD1 . ASN A 1 68 ? 51.357 14.837 10.425 1.00 70.20 ? 69 ASN A OD1 1 ATOM 415 N ND2 . ASN A 1 68 ? 50.465 16.663 11.512 1.00 88.01 ? 69 ASN A ND2 1 ATOM 416 N N . GLU A 1 69 ? 52.453 15.179 14.734 1.00 40.82 ? 70 GLU A N 1 ATOM 417 C CA . GLU A 1 69 ? 51.623 14.781 15.854 1.00 38.90 ? 70 GLU A CA 1 ATOM 418 C C . GLU A 1 69 ? 50.923 15.987 16.443 1.00 41.47 ? 70 GLU A C 1 ATOM 419 O O . GLU A 1 69 ? 51.374 17.112 16.258 1.00 39.81 ? 70 GLU A O 1 ATOM 420 C CB . GLU A 1 69 ? 52.490 14.107 16.908 1.00 40.50 ? 70 GLU A CB 1 ATOM 421 C CG . GLU A 1 69 ? 52.947 12.706 16.506 1.00 45.85 ? 70 GLU A CG 1 ATOM 422 C CD . GLU A 1 69 ? 53.817 11.976 17.506 1.00 69.63 ? 70 GLU A CD 1 ATOM 423 O OE1 . GLU A 1 69 ? 53.614 12.169 18.725 1.00 75.10 ? 70 GLU A OE1 1 ATOM 424 O OE2 . GLU A 1 69 ? 54.691 11.192 17.071 1.00 72.53 ? 70 GLU A OE2 1 ATOM 425 N N . THR A 1 70 ? 49.807 15.758 17.150 1.00 39.14 ? 71 THR A N 1 ATOM 426 C CA . THR A 1 70 ? 49.009 16.810 17.770 1.00 38.51 ? 71 THR A CA 1 ATOM 427 C C . THR A 1 70 ? 48.308 16.301 19.005 1.00 43.67 ? 71 THR A C 1 ATOM 428 O O . THR A 1 70 ? 47.811 15.178 19.008 1.00 45.06 ? 71 THR A O 1 ATOM 429 C CB . THR A 1 70 ? 48.007 17.458 16.761 1.00 43.41 ? 71 THR A CB 1 ATOM 430 O OG1 . THR A 1 70 ? 47.193 18.427 17.432 1.00 39.17 ? 71 THR A OG1 1 ATOM 431 C CG2 . THR A 1 70 ? 47.101 16.447 16.066 1.00 37.66 ? 71 THR A CG2 1 ATOM 432 N N . SER A 1 71 ? 48.248 17.134 20.040 1.00 38.02 ? 72 SER A N 1 ATOM 433 C CA . SER A 1 71 ? 47.490 16.854 21.236 1.00 38.21 ? 72 SER A CA 1 ATOM 434 C C . SER A 1 71 ? 46.469 17.997 21.383 1.00 46.34 ? 72 SER A C 1 ATOM 435 O O . SER A 1 71 ? 45.880 18.163 22.447 1.00 46.52 ? 72 SER A O 1 ATOM 436 C CB . SER A 1 71 ? 48.403 16.712 22.457 1.00 40.44 ? 72 SER A CB 1 ATOM 437 O OG . SER A 1 71 ? 48.980 17.925 22.908 1.00 43.16 ? 72 SER A OG 1 ATOM 438 N N . CYS A 1 72 ? 46.231 18.745 20.271 1.00 46.03 ? 73 CYS A N 1 ATOM 439 C CA . CYS A 1 72 ? 45.347 19.917 20.203 1.00 47.93 ? 73 CYS A CA 1 ATOM 440 C C . CYS A 1 72 ? 44.014 19.645 19.545 1.00 57.26 ? 73 CYS A C 1 ATOM 441 O O . CYS A 1 72 ? 43.408 20.577 19.005 1.00 57.91 ? 73 CYS A O 1 ATOM 442 C CB . CYS A 1 72 ? 46.046 21.104 19.539 1.00 48.11 ? 73 CYS A CB 1 ATOM 443 S SG . CYS A 1 72 ? 47.454 21.763 20.456 1.00 52.30 ? 73 CYS A SG 1 ATOM 444 N N . LEU A 1 73 ? 43.540 18.399 19.581 1.00 57.54 ? 74 LEU A N 1 ATOM 445 C CA . LEU A 1 73 ? 42.243 18.084 18.972 1.00 58.20 ? 74 LEU A CA 1 ATOM 446 C C . LEU A 1 73 ? 41.081 18.743 19.728 1.00 59.18 ? 74 LEU A C 1 ATOM 447 O O . LEU A 1 73 ? 41.043 18.745 20.975 1.00 56.28 ? 74 LEU A O 1 ATOM 448 C CB . LEU A 1 73 ? 42.044 16.581 18.754 1.00 59.10 ? 74 LEU A CB 1 ATOM 449 C CG . LEU A 1 73 ? 43.131 15.884 17.878 1.00 65.92 ? 74 LEU A CG 1 ATOM 450 C CD1 . LEU A 1 73 ? 42.846 14.387 17.725 1.00 65.98 ? 74 LEU A CD1 1 ATOM 451 C CD2 . LEU A 1 73 ? 43.299 16.564 16.486 1.00 67.96 ? 74 LEU A CD2 1 ATOM 452 N N . GLY A 1 74 ? 40.225 19.405 18.948 1.00 55.24 ? 75 GLY A N 1 ATOM 453 C CA . GLY A 1 74 ? 39.072 20.145 19.454 1.00 54.89 ? 75 GLY A CA 1 ATOM 454 C C . GLY A 1 74 ? 39.369 21.584 19.838 1.00 58.56 ? 75 GLY A C 1 ATOM 455 O O . GLY A 1 74 ? 38.506 22.274 20.396 1.00 58.83 ? 75 GLY A O 1 ATOM 456 N N . ARG A 1 75 ? 40.601 22.053 19.548 1.00 52.91 ? 76 ARG A N 1 ATOM 457 C CA . ARG A 1 75 ? 41.012 23.414 19.874 1.00 50.42 ? 76 ARG A CA 1 ATOM 458 C C . ARG A 1 75 ? 41.120 24.312 18.623 1.00 51.94 ? 76 ARG A C 1 ATOM 459 O O . ARG A 1 75 ? 41.436 25.484 18.768 1.00 51.09 ? 76 ARG A O 1 ATOM 460 C CB . ARG A 1 75 ? 42.318 23.424 20.684 1.00 46.82 ? 76 ARG A CB 1 ATOM 461 C CG . ARG A 1 75 ? 42.415 22.374 21.769 1.00 49.95 ? 76 ARG A CG 1 ATOM 462 C CD . ARG A 1 75 ? 42.160 22.964 23.118 1.00 58.73 ? 76 ARG A CD 1 ATOM 463 N NE . ARG A 1 75 ? 42.801 22.188 24.177 1.00 83.81 ? 76 ARG A NE 1 ATOM 464 C CZ . ARG A 1 75 ? 43.931 22.533 24.790 1.00 106.32 ? 76 ARG A CZ 1 ATOM 465 N NH1 . ARG A 1 75 ? 44.567 23.650 24.451 1.00 95.70 ? 76 ARG A NH1 1 ATOM 466 N NH2 . ARG A 1 75 ? 44.439 21.759 25.740 1.00 94.13 ? 76 ARG A NH2 1 ATOM 467 N N . ASN A 1 76 ? 40.866 23.781 17.410 1.00 48.15 ? 77 ASN A N 1 ATOM 468 C CA . ASN A 1 76 ? 40.935 24.540 16.141 1.00 48.39 ? 77 ASN A CA 1 ATOM 469 C C . ASN A 1 76 ? 42.332 25.110 15.791 1.00 50.82 ? 77 ASN A C 1 ATOM 470 O O . ASN A 1 76 ? 42.457 26.034 14.980 1.00 50.15 ? 77 ASN A O 1 ATOM 471 C CB . ASN A 1 76 ? 39.869 25.633 16.099 1.00 54.57 ? 77 ASN A CB 1 ATOM 472 C CG . ASN A 1 76 ? 38.613 25.269 15.381 1.00 85.66 ? 77 ASN A CG 1 ATOM 473 O OD1 . ASN A 1 76 ? 38.625 24.614 14.337 1.00 69.45 ? 77 ASN A OD1 1 ATOM 474 N ND2 . ASN A 1 76 ? 37.506 25.726 15.916 1.00 100.65 ? 77 ASN A ND2 1 ATOM 475 N N . ILE A 1 77 ? 43.374 24.528 16.406 1.00 45.38 ? 78 ILE A N 1 ATOM 476 C CA . ILE A 1 77 ? 44.779 24.854 16.233 1.00 43.62 ? 78 ILE A CA 1 ATOM 477 C C . ILE A 1 77 ? 45.383 23.803 15.288 1.00 46.73 ? 78 ILE A C 1 ATOM 478 O O . ILE A 1 77 ? 45.318 22.599 15.565 1.00 46.85 ? 78 ILE A O 1 ATOM 479 C CB . ILE A 1 77 ? 45.501 24.903 17.619 1.00 45.64 ? 78 ILE A CB 1 ATOM 480 C CG1 . ILE A 1 77 ? 44.983 26.079 18.468 1.00 45.36 ? 78 ILE A CG1 1 ATOM 481 C CG2 . ILE A 1 77 ? 47.025 24.952 17.468 1.00 44.50 ? 78 ILE A CG2 1 ATOM 482 C CD1 . ILE A 1 77 ? 45.125 25.894 19.967 1.00 51.02 ? 78 ILE A CD1 1 ATOM 483 N N . THR A 1 78 ? 45.958 24.265 14.169 1.00 41.41 ? 79 THR A N 1 ATOM 484 C CA . THR A 1 78 ? 46.615 23.423 13.158 1.00 40.59 ? 79 THR A CA 1 ATOM 485 C C . THR A 1 78 ? 47.802 24.185 12.552 1.00 43.99 ? 79 THR A C 1 ATOM 486 O O . THR A 1 78 ? 47.978 25.375 12.805 1.00 44.30 ? 79 THR A O 1 ATOM 487 C CB . THR A 1 78 ? 45.630 23.087 11.998 1.00 52.00 ? 79 THR A CB 1 ATOM 488 O OG1 . THR A 1 78 ? 45.330 24.287 11.262 1.00 56.14 ? 79 THR A OG1 1 ATOM 489 C CG2 . THR A 1 78 ? 44.328 22.387 12.470 1.00 48.37 ? 79 THR A CG2 1 ATOM 490 N N . TRP A 1 79 ? 48.576 23.506 11.706 1.00 41.16 ? 80 TRP A N 1 ATOM 491 C CA . TRP A 1 79 ? 49.636 24.075 10.879 1.00 40.84 ? 80 TRP A CA 1 ATOM 492 C C . TRP A 1 79 ? 48.905 24.823 9.754 1.00 44.94 ? 80 TRP A C 1 ATOM 493 O O . TRP A 1 79 ? 47.966 24.271 9.171 1.00 44.73 ? 80 TRP A O 1 ATOM 494 C CB . TRP A 1 79 ? 50.491 22.950 10.255 1.00 39.34 ? 80 TRP A CB 1 ATOM 495 C CG . TRP A 1 79 ? 51.367 22.264 11.251 1.00 40.64 ? 80 TRP A CG 1 ATOM 496 C CD1 . TRP A 1 79 ? 51.190 21.023 11.788 1.00 43.17 ? 80 TRP A CD1 1 ATOM 497 C CD2 . TRP A 1 79 ? 52.530 22.813 11.882 1.00 40.93 ? 80 TRP A CD2 1 ATOM 498 N NE1 . TRP A 1 79 ? 52.188 20.752 12.700 1.00 42.28 ? 80 TRP A NE1 1 ATOM 499 C CE2 . TRP A 1 79 ? 53.017 21.836 12.788 1.00 44.40 ? 80 TRP A CE2 1 ATOM 500 C CE3 . TRP A 1 79 ? 53.226 24.032 11.754 1.00 42.22 ? 80 TRP A CE3 1 ATOM 501 C CZ2 . TRP A 1 79 ? 54.161 22.034 13.559 1.00 43.98 ? 80 TRP A CZ2 1 ATOM 502 C CZ3 . TRP A 1 79 ? 54.382 24.215 12.502 1.00 44.01 ? 80 TRP A CZ3 1 ATOM 503 C CH2 . TRP A 1 79 ? 54.837 23.221 13.388 1.00 44.56 ? 80 TRP A CH2 1 ATOM 504 N N . ALA A 1 80 ? 49.282 26.077 9.473 1.00 43.05 ? 81 ALA A N 1 ATOM 505 C CA . ALA A 1 80 ? 48.655 26.883 8.404 1.00 43.46 ? 81 ALA A CA 1 ATOM 506 C C . ALA A 1 80 ? 48.742 26.110 7.069 1.00 49.60 ? 81 ALA A C 1 ATOM 507 O O . ALA A 1 80 ? 47.767 26.018 6.335 1.00 50.62 ? 81 ALA A O 1 ATOM 508 C CB . ALA A 1 80 ? 49.345 28.241 8.289 1.00 43.78 ? 81 ALA A CB 1 ATOM 509 N N . SER A 1 81 ? 49.892 25.490 6.829 1.00 46.94 ? 82 SER A N 1 ATOM 510 C CA . SER A 1 81 ? 50.217 24.636 5.686 1.00 48.07 ? 82 SER A CA 1 ATOM 511 C C . SER A 1 81 ? 51.339 23.688 6.164 1.00 53.67 ? 82 SER A C 1 ATOM 512 O O . SER A 1 81 ? 51.848 23.871 7.278 1.00 53.59 ? 82 SER A O 1 ATOM 513 C CB . SER A 1 81 ? 50.681 25.472 4.492 1.00 50.32 ? 82 SER A CB 1 ATOM 514 O OG . SER A 1 81 ? 51.817 26.256 4.812 1.00 57.65 ? 82 SER A OG 1 ATOM 515 N N . THR A 1 82 ? 51.716 22.691 5.355 1.00 50.97 ? 83 THR A N 1 ATOM 516 C CA . THR A 1 82 ? 52.805 21.788 5.713 1.00 51.40 ? 83 THR A CA 1 ATOM 517 C C . THR A 1 82 ? 54.075 22.618 5.976 1.00 57.39 ? 83 THR A C 1 ATOM 518 O O . THR A 1 82 ? 54.477 23.404 5.119 1.00 57.06 ? 83 THR A O 1 ATOM 519 C CB . THR A 1 82 ? 53.000 20.700 4.654 1.00 53.13 ? 83 THR A CB 1 ATOM 520 O OG1 . THR A 1 82 ? 51.781 19.987 4.516 1.00 52.28 ? 83 THR A OG1 1 ATOM 521 C CG2 . THR A 1 82 ? 54.102 19.718 5.025 1.00 52.25 ? 83 THR A CG2 1 ATOM 522 N N . PRO A 1 83 ? 54.677 22.507 7.175 1.00 55.54 ? 84 PRO A N 1 ATOM 523 C CA . PRO A 1 83 ? 55.854 23.342 7.466 1.00 55.89 ? 84 PRO A CA 1 ATOM 524 C C . PRO A 1 83 ? 57.140 22.963 6.732 1.00 63.27 ? 84 PRO A C 1 ATOM 525 O O . PRO A 1 83 ? 57.507 21.776 6.656 1.00 63.55 ? 84 PRO A O 1 ATOM 526 C CB . PRO A 1 83 ? 55.989 23.253 8.987 1.00 56.79 ? 84 PRO A CB 1 ATOM 527 C CG . PRO A 1 83 ? 55.319 22.003 9.359 1.00 60.05 ? 84 PRO A CG 1 ATOM 528 C CD . PRO A 1 83 ? 54.295 21.668 8.335 1.00 55.54 ? 84 PRO A CD 1 ATOM 529 N N . ASP A 1 84 ? 57.815 24.009 6.184 1.00 61.00 ? 85 ASP A N 1 ATOM 530 C CA . ASP A 1 84 ? 59.093 23.918 5.475 1.00 61.20 ? 85 ASP A CA 1 ATOM 531 C C . ASP A 1 84 ? 60.005 25.130 5.827 1.00 65.48 ? 85 ASP A C 1 ATOM 532 O O . ASP A 1 84 ? 60.767 25.035 6.799 1.00 65.26 ? 85 ASP A O 1 ATOM 533 C CB . ASP A 1 84 ? 58.882 23.731 3.959 1.00 62.98 ? 85 ASP A CB 1 ATOM 534 C CG . ASP A 1 84 ? 60.159 23.521 3.161 1.00 78.98 ? 85 ASP A CG 1 ATOM 535 O OD1 . ASP A 1 84 ? 61.165 23.027 3.750 1.00 80.30 ? 85 ASP A OD1 1 ATOM 536 O OD2 . ASP A 1 84 ? 60.157 23.836 1.944 1.00 87.19 ? 85 ASP A OD2 1 ATOM 537 N N . HIS A 1 85 ? 59.907 26.261 5.071 1.00 61.09 ? 86 HIS A N 1 ATOM 538 C CA . HIS A 1 85 ? 60.712 27.478 5.286 1.00 60.81 ? 86 HIS A CA 1 ATOM 539 C C . HIS A 1 85 ? 59.975 28.599 6.020 1.00 55.16 ? 86 HIS A C 1 ATOM 540 O O . HIS A 1 85 ? 60.600 29.540 6.511 1.00 51.22 ? 86 HIS A O 1 ATOM 541 C CB . HIS A 1 85 ? 61.306 27.985 3.968 1.00 64.75 ? 86 HIS A CB 1 ATOM 542 C CG . HIS A 1 85 ? 62.216 26.997 3.312 1.00 71.28 ? 86 HIS A CG 1 ATOM 543 N ND1 . HIS A 1 85 ? 63.165 26.268 4.046 1.00 74.65 ? 86 HIS A ND1 1 ATOM 544 C CD2 . HIS A 1 85 ? 62.304 26.642 2.007 1.00 75.06 ? 86 HIS A CD2 1 ATOM 545 C CE1 . HIS A 1 85 ? 63.791 25.511 3.158 1.00 75.08 ? 86 HIS A CE1 1 ATOM 546 N NE2 . HIS A 1 85 ? 63.310 25.696 1.918 1.00 75.44 ? 86 HIS A NE2 1 ATOM 547 N N . SER A 1 86 ? 58.638 28.475 6.105 1.00 49.33 ? 87 SER A N 1 ATOM 548 C CA . SER A 1 86 ? 57.740 29.388 6.795 1.00 47.13 ? 87 SER A CA 1 ATOM 549 C C . SER A 1 86 ? 56.786 28.613 7.756 1.00 45.04 ? 87 SER A C 1 ATOM 550 O O . SER A 1 86 ? 55.581 28.684 7.541 1.00 44.57 ? 87 SER A O 1 ATOM 551 C CB . SER A 1 86 ? 56.964 30.230 5.787 1.00 49.88 ? 87 SER A CB 1 ATOM 552 O OG . SER A 1 86 ? 57.818 31.122 5.089 1.00 54.96 ? 87 SER A OG 1 ATOM 553 N N . PRO A 1 87 ? 57.283 27.885 8.810 1.00 37.45 ? 88 PRO A N 1 ATOM 554 C CA . PRO A 1 87 ? 56.357 27.190 9.739 1.00 37.09 ? 88 PRO A CA 1 ATOM 555 C C . PRO A 1 87 ? 55.445 28.192 10.447 1.00 41.31 ? 88 PRO A C 1 ATOM 556 O O . PRO A 1 87 ? 55.906 29.222 10.951 1.00 40.94 ? 88 PRO A O 1 ATOM 557 C CB . PRO A 1 87 ? 57.283 26.466 10.708 1.00 37.69 ? 88 PRO A CB 1 ATOM 558 C CG . PRO A 1 87 ? 58.548 27.204 10.634 1.00 40.57 ? 88 PRO A CG 1 ATOM 559 C CD . PRO A 1 87 ? 58.679 27.693 9.237 1.00 36.41 ? 88 PRO A CD 1 ATOM 560 N N . GLU A 1 88 ? 54.142 27.921 10.392 1.00 37.54 ? 89 GLU A N 1 ATOM 561 C CA . GLU A 1 88 ? 53.119 28.817 10.868 1.00 37.27 ? 89 GLU A CA 1 ATOM 562 C C . GLU A 1 88 ? 51.953 28.074 11.495 1.00 40.89 ? 89 GLU A C 1 ATOM 563 O O . GLU A 1 88 ? 51.392 27.149 10.900 1.00 40.66 ? 89 GLU A O 1 ATOM 564 C CB . GLU A 1 88 ? 52.634 29.648 9.660 1.00 39.31 ? 89 GLU A CB 1 ATOM 565 C CG . GLU A 1 88 ? 51.911 30.947 9.979 1.00 48.95 ? 89 GLU A CG 1 ATOM 566 C CD . GLU A 1 88 ? 51.639 31.829 8.775 1.00 65.19 ? 89 GLU A CD 1 ATOM 567 O OE1 . GLU A 1 88 ? 51.340 31.290 7.685 1.00 62.03 ? 89 GLU A OE1 1 ATOM 568 O OE2 . GLU A 1 88 ? 51.710 33.069 8.932 1.00 55.90 ? 89 GLU A OE2 1 ATOM 569 N N . LEU A 1 89 ? 51.571 28.505 12.696 1.00 37.62 ? 90 LEU A N 1 ATOM 570 C CA . LEU A 1 89 ? 50.424 27.964 13.412 1.00 37.11 ? 90 LEU A CA 1 ATOM 571 C C . LEU A 1 89 ? 49.225 28.799 13.000 1.00 40.65 ? 90 LEU A C 1 ATOM 572 O O . LEU A 1 89 ? 49.329 30.019 12.866 1.00 39.66 ? 90 LEU A O 1 ATOM 573 C CB . LEU A 1 89 ? 50.651 28.070 14.929 1.00 37.27 ? 90 LEU A CB 1 ATOM 574 C CG . LEU A 1 89 ? 49.577 27.472 15.856 1.00 41.59 ? 90 LEU A CG 1 ATOM 575 C CD1 . LEU A 1 89 ? 50.201 26.782 17.032 1.00 41.23 ? 90 LEU A CD1 1 ATOM 576 C CD2 . LEU A 1 89 ? 48.623 28.550 16.370 1.00 41.72 ? 90 LEU A CD2 1 ATOM 577 N N . GLN A 1 90 ? 48.089 28.133 12.824 1.00 38.70 ? 91 GLN A N 1 ATOM 578 C CA . GLN A 1 90 ? 46.820 28.737 12.483 1.00 38.69 ? 91 GLN A CA 1 ATOM 579 C C . GLN A 1 90 ? 45.753 28.408 13.517 1.00 42.74 ? 91 GLN A C 1 ATOM 580 O O . GLN A 1 90 ? 45.579 27.245 13.896 1.00 40.66 ? 91 GLN A O 1 ATOM 581 C CB . GLN A 1 90 ? 46.343 28.200 11.144 1.00 40.34 ? 91 GLN A CB 1 ATOM 582 C CG . GLN A 1 90 ? 45.141 28.937 10.573 1.00 56.36 ? 91 GLN A CG 1 ATOM 583 C CD . GLN A 1 90 ? 44.634 28.245 9.332 1.00 66.12 ? 91 GLN A CD 1 ATOM 584 O OE1 . GLN A 1 90 ? 45.105 28.483 8.216 1.00 62.31 ? 91 GLN A OE1 1 ATOM 585 N NE2 . GLN A 1 90 ? 43.631 27.410 9.512 1.00 49.17 ? 91 GLN A NE2 1 ATOM 586 N N . ILE A 1 91 ? 45.020 29.451 13.942 1.00 39.62 ? 92 ILE A N 1 ATOM 587 C CA . ILE A 1 91 ? 43.791 29.335 14.711 1.00 38.42 ? 92 ILE A CA 1 ATOM 588 C C . ILE A 1 91 ? 42.729 29.731 13.670 1.00 47.22 ? 92 ILE A C 1 ATOM 589 O O . ILE A 1 91 ? 42.691 30.893 13.244 1.00 47.20 ? 92 ILE A O 1 ATOM 590 C CB . ILE A 1 91 ? 43.721 30.187 15.995 1.00 39.41 ? 92 ILE A CB 1 ATOM 591 C CG1 . ILE A 1 91 ? 44.928 29.906 16.920 1.00 37.83 ? 92 ILE A CG1 1 ATOM 592 C CG2 . ILE A 1 91 ? 42.405 29.885 16.697 1.00 39.04 ? 92 ILE A CG2 1 ATOM 593 C CD1 . ILE A 1 91 ? 45.171 30.892 17.979 1.00 30.01 ? 92 ILE A CD1 1 ATOM 594 N N . SER A 1 92 ? 41.968 28.734 13.161 1.00 46.85 ? 93 SER A N 1 ATOM 595 C CA . SER A 1 92 ? 40.912 28.927 12.152 1.00 47.37 ? 93 SER A CA 1 ATOM 596 C C . SER A 1 92 ? 39.884 29.979 12.606 1.00 51.88 ? 93 SER A C 1 ATOM 597 O O . SER A 1 92 ? 39.580 30.887 11.832 1.00 52.41 ? 93 SER A O 1 ATOM 598 C CB . SER A 1 92 ? 40.233 27.600 11.822 1.00 52.16 ? 93 SER A CB 1 ATOM 599 O OG . SER A 1 92 ? 39.630 27.010 12.965 1.00 60.72 ? 93 SER A OG 1 ATOM 600 N N . ALA A 1 93 ? 39.395 29.883 13.877 1.00 48.21 ? 94 ALA A N 1 ATOM 601 C CA . ALA A 1 93 ? 38.460 30.855 14.487 1.00 47.30 ? 94 ALA A CA 1 ATOM 602 C C . ALA A 1 93 ? 38.827 31.064 15.941 1.00 49.15 ? 94 ALA A C 1 ATOM 603 O O . ALA A 1 93 ? 38.703 30.141 16.748 1.00 49.62 ? 94 ALA A O 1 ATOM 604 C CB . ALA A 1 93 ? 37.012 30.392 14.364 1.00 47.61 ? 94 ALA A CB 1 ATOM 605 N N . VAL A 1 94 ? 39.322 32.269 16.265 1.00 43.38 ? 95 VAL A N 1 ATOM 606 C CA . VAL A 1 94 ? 39.747 32.645 17.614 1.00 42.24 ? 95 VAL A CA 1 ATOM 607 C C . VAL A 1 94 ? 38.569 32.688 18.593 1.00 46.95 ? 95 VAL A C 1 ATOM 608 O O . VAL A 1 94 ? 37.483 33.141 18.248 1.00 48.18 ? 95 VAL A O 1 ATOM 609 C CB . VAL A 1 94 ? 40.586 33.953 17.555 1.00 44.81 ? 95 VAL A CB 1 ATOM 610 C CG1 . VAL A 1 94 ? 40.595 34.697 18.874 1.00 43.83 ? 95 VAL A CG1 1 ATOM 611 C CG2 . VAL A 1 94 ? 42.006 33.667 17.082 1.00 44.57 ? 95 VAL A CG2 1 ATOM 612 N N . ALA A 1 95 ? 38.775 32.148 19.795 1.00 42.73 ? 96 ALA A N 1 ATOM 613 C CA . ALA A 1 95 ? 37.793 32.094 20.879 1.00 40.63 ? 96 ALA A CA 1 ATOM 614 C C . ALA A 1 95 ? 38.522 32.441 22.175 1.00 43.22 ? 96 ALA A C 1 ATOM 615 O O . ALA A 1 95 ? 39.749 32.473 22.184 1.00 42.44 ? 96 ALA A O 1 ATOM 616 C CB . ALA A 1 95 ? 37.187 30.698 20.951 1.00 41.04 ? 96 ALA A CB 1 ATOM 617 N N . LEU A 1 96 ? 37.801 32.738 23.257 1.00 41.61 ? 97 LEU A N 1 ATOM 618 C CA . LEU A 1 96 ? 38.452 33.057 24.537 1.00 42.11 ? 97 LEU A CA 1 ATOM 619 C C . LEU A 1 96 ? 39.472 31.991 25.022 1.00 46.57 ? 97 LEU A C 1 ATOM 620 O O . LEU A 1 96 ? 40.517 32.351 25.581 1.00 47.67 ? 97 LEU A O 1 ATOM 621 C CB . LEU A 1 96 ? 37.427 33.329 25.619 1.00 41.85 ? 97 LEU A CB 1 ATOM 622 C CG . LEU A 1 96 ? 36.742 34.681 25.576 1.00 45.61 ? 97 LEU A CG 1 ATOM 623 C CD1 . LEU A 1 96 ? 35.705 34.773 26.677 1.00 46.44 ? 97 LEU A CD1 1 ATOM 624 C CD2 . LEU A 1 96 ? 37.728 35.787 25.798 1.00 43.78 ? 97 LEU A CD2 1 ATOM 625 N N . GLN A 1 97 ? 39.196 30.706 24.749 1.00 41.94 ? 98 GLN A N 1 ATOM 626 C CA . GLN A 1 97 ? 40.072 29.589 25.117 1.00 41.72 ? 98 GLN A CA 1 ATOM 627 C C . GLN A 1 97 ? 41.478 29.683 24.479 1.00 44.91 ? 98 GLN A C 1 ATOM 628 O O . GLN A 1 97 ? 42.390 29.030 24.965 1.00 46.12 ? 98 GLN A O 1 ATOM 629 C CB . GLN A 1 97 ? 39.417 28.233 24.787 1.00 43.06 ? 98 GLN A CB 1 ATOM 630 C CG . GLN A 1 97 ? 39.175 27.970 23.293 1.00 56.33 ? 98 GLN A CG 1 ATOM 631 C CD . GLN A 1 97 ? 39.214 26.500 22.954 1.00 81.37 ? 98 GLN A CD 1 ATOM 632 O OE1 . GLN A 1 97 ? 40.090 25.756 23.401 1.00 80.22 ? 98 GLN A OE1 1 ATOM 633 N NE2 . GLN A 1 97 ? 38.318 26.062 22.081 1.00 76.20 ? 98 GLN A NE2 1 ATOM 634 N N . HIS A 1 98 ? 41.650 30.499 23.417 1.00 38.29 ? 99 HIS A N 1 ATOM 635 C CA . HIS A 1 98 ? 42.917 30.671 22.705 1.00 36.92 ? 99 HIS A CA 1 ATOM 636 C C . HIS A 1 98 ? 43.923 31.595 23.346 1.00 39.06 ? 99 HIS A C 1 ATOM 637 O O . HIS A 1 98 ? 45.089 31.568 22.963 1.00 38.23 ? 99 HIS A O 1 ATOM 638 C CB . HIS A 1 98 ? 42.691 31.021 21.243 1.00 36.83 ? 99 HIS A CB 1 ATOM 639 C CG . HIS A 1 98 ? 42.020 29.926 20.501 1.00 40.29 ? 99 HIS A CG 1 ATOM 640 N ND1 . HIS A 1 98 ? 40.790 30.105 19.933 1.00 42.67 ? 99 HIS A ND1 1 ATOM 641 C CD2 . HIS A 1 98 ? 42.419 28.652 20.298 1.00 42.50 ? 99 HIS A CD2 1 ATOM 642 C CE1 . HIS A 1 98 ? 40.495 28.957 19.357 1.00 42.68 ? 99 HIS A CE1 1 ATOM 643 N NE2 . HIS A 1 98 ? 41.437 28.047 19.581 1.00 42.94 ? 99 HIS A NE2 1 ATOM 644 N N . GLU A 1 99 ? 43.484 32.404 24.314 1.00 33.62 ? 100 GLU A N 1 ATOM 645 C CA . GLU A 1 99 ? 44.359 33.315 25.015 1.00 33.54 ? 100 GLU A CA 1 ATOM 646 C C . GLU A 1 99 ? 45.408 32.520 25.810 1.00 41.77 ? 100 GLU A C 1 ATOM 647 O O . GLU A 1 99 ? 45.076 31.628 26.595 1.00 43.49 ? 100 GLU A O 1 ATOM 648 C CB . GLU A 1 99 ? 43.528 34.199 25.941 1.00 34.15 ? 100 GLU A CB 1 ATOM 649 C CG . GLU A 1 99 ? 44.344 35.168 26.774 1.00 38.13 ? 100 GLU A CG 1 ATOM 650 C CD . GLU A 1 99 ? 43.656 36.492 27.069 1.00 59.29 ? 100 GLU A CD 1 ATOM 651 O OE1 . GLU A 1 99 ? 42.978 37.033 26.164 1.00 45.89 ? 100 GLU A OE1 1 ATOM 652 O OE2 . GLU A 1 99 ? 43.866 37.035 28.176 1.00 54.04 ? 100 GLU A OE2 1 ATOM 653 N N . GLY A 1 100 ? 46.662 32.855 25.583 1.00 39.02 ? 101 GLY A N 1 ATOM 654 C CA . GLY A 1 100 ? 47.794 32.228 26.248 1.00 37.62 ? 101 GLY A CA 1 ATOM 655 C C . GLY A 1 100 ? 49.106 32.458 25.533 1.00 38.32 ? 101 GLY A C 1 ATOM 656 O O . GLY A 1 100 ? 49.241 33.383 24.725 1.00 35.17 ? 101 GLY A O 1 ATOM 657 N N . THR A 1 101 ? 50.075 31.578 25.827 1.00 35.10 ? 102 THR A N 1 ATOM 658 C CA . THR A 1 101 ? 51.448 31.607 25.304 1.00 33.28 ? 102 THR A CA 1 ATOM 659 C C . THR A 1 101 ? 51.617 30.549 24.262 1.00 34.33 ? 102 THR A C 1 ATOM 660 O O . THR A 1 101 ? 51.203 29.402 24.464 1.00 33.25 ? 102 THR A O 1 ATOM 661 C CB . THR A 1 101 ? 52.436 31.460 26.469 1.00 40.30 ? 102 THR A CB 1 ATOM 662 O OG1 . THR A 1 101 ? 52.196 32.550 27.351 1.00 40.98 ? 102 THR A OG1 1 ATOM 663 C CG2 . THR A 1 101 ? 53.876 31.558 26.033 1.00 43.26 ? 102 THR A CG2 1 ATOM 664 N N . TYR A 1 102 ? 52.181 30.942 23.117 1.00 29.25 ? 103 TYR A N 1 ATOM 665 C CA . TYR A 1 102 ? 52.407 30.038 21.998 1.00 27.99 ? 103 TYR A CA 1 ATOM 666 C C . TYR A 1 102 ? 53.888 30.063 21.745 1.00 33.32 ? 103 TYR A C 1 ATOM 667 O O . TYR A 1 102 ? 54.417 31.095 21.315 1.00 34.14 ? 103 TYR A O 1 ATOM 668 C CB . TYR A 1 102 ? 51.589 30.481 20.764 1.00 27.16 ? 103 TYR A CB 1 ATOM 669 C CG . TYR A 1 102 ? 50.093 30.317 20.912 1.00 25.70 ? 103 TYR A CG 1 ATOM 670 C CD1 . TYR A 1 102 ? 49.366 31.128 21.771 1.00 26.62 ? 103 TYR A CD1 1 ATOM 671 C CD2 . TYR A 1 102 ? 49.391 29.403 20.133 1.00 26.55 ? 103 TYR A CD2 1 ATOM 672 C CE1 . TYR A 1 102 ? 47.999 30.942 21.959 1.00 27.40 ? 103 TYR A CE1 1 ATOM 673 C CE2 . TYR A 1 102 ? 48.007 29.255 20.261 1.00 25.68 ? 103 TYR A CE2 1 ATOM 674 C CZ . TYR A 1 102 ? 47.324 30.002 21.204 1.00 31.34 ? 103 TYR A CZ 1 ATOM 675 O OH . TYR A 1 102 ? 45.971 29.837 21.390 1.00 32.93 ? 103 TYR A OH 1 ATOM 676 N N . THR A 1 103 ? 54.579 28.954 22.085 1.00 28.92 ? 104 THR A N 1 ATOM 677 C CA . THR A 1 103 ? 56.034 28.840 21.952 1.00 27.79 ? 104 THR A CA 1 ATOM 678 C C . THR A 1 103 ? 56.414 27.908 20.834 1.00 33.06 ? 104 THR A C 1 ATOM 679 O O . THR A 1 103 ? 55.975 26.755 20.816 1.00 31.98 ? 104 THR A O 1 ATOM 680 C CB . THR A 1 103 ? 56.665 28.427 23.274 1.00 28.91 ? 104 THR A CB 1 ATOM 681 O OG1 . THR A 1 103 ? 56.255 29.336 24.292 1.00 30.71 ? 104 THR A OG1 1 ATOM 682 C CG2 . THR A 1 103 ? 58.178 28.380 23.217 1.00 25.33 ? 104 THR A CG2 1 ATOM 683 N N . CYS A 1 104 ? 57.208 28.413 19.889 1.00 31.25 ? 105 CYS A N 1 ATOM 684 C CA . CYS A 1 104 ? 57.694 27.592 18.803 1.00 33.24 ? 105 CYS A CA 1 ATOM 685 C C . CYS A 1 104 ? 59.127 27.214 19.119 1.00 34.87 ? 105 CYS A C 1 ATOM 686 O O . CYS A 1 104 ? 59.989 28.090 19.244 1.00 34.41 ? 105 CYS A O 1 ATOM 687 C CB . CYS A 1 104 ? 57.591 28.320 17.477 1.00 36.27 ? 105 CYS A CB 1 ATOM 688 S SG . CYS A 1 104 ? 58.009 27.288 16.061 1.00 42.36 ? 105 CYS A SG 1 ATOM 689 N N . GLU A 1 105 ? 59.354 25.915 19.342 1.00 30.48 ? 106 GLU A N 1 ATOM 690 C CA . GLU A 1 105 ? 60.656 25.341 19.680 1.00 30.22 ? 106 GLU A CA 1 ATOM 691 C C . GLU A 1 105 ? 61.186 24.723 18.442 1.00 32.36 ? 106 GLU A C 1 ATOM 692 O O . GLU A 1 105 ? 60.522 23.866 17.846 1.00 32.76 ? 106 GLU A O 1 ATOM 693 C CB . GLU A 1 105 ? 60.536 24.268 20.757 1.00 32.14 ? 106 GLU A CB 1 ATOM 694 C CG . GLU A 1 105 ? 60.282 24.810 22.145 1.00 50.42 ? 106 GLU A CG 1 ATOM 695 C CD . GLU A 1 105 ? 60.361 23.810 23.291 1.00 70.74 ? 106 GLU A CD 1 ATOM 696 O OE1 . GLU A 1 105 ? 60.385 22.580 23.031 1.00 40.45 ? 106 GLU A OE1 1 ATOM 697 O OE2 . GLU A 1 105 ? 60.333 24.270 24.459 1.00 59.49 ? 106 GLU A OE2 1 ATOM 698 N N . ILE A 1 106 ? 62.352 25.209 17.996 1.00 27.21 ? 107 ILE A N 1 ATOM 699 C CA . ILE A 1 106 ? 62.964 24.710 16.779 1.00 26.94 ? 107 ILE A CA 1 ATOM 700 C C . ILE A 1 106 ? 64.227 23.961 17.143 1.00 30.69 ? 107 ILE A C 1 ATOM 701 O O . ILE A 1 106 ? 65.090 24.505 17.829 1.00 28.73 ? 107 ILE A O 1 ATOM 702 C CB . ILE A 1 106 ? 63.248 25.853 15.736 1.00 29.91 ? 107 ILE A CB 1 ATOM 703 C CG1 . ILE A 1 106 ? 62.000 26.706 15.429 1.00 29.54 ? 107 ILE A CG1 1 ATOM 704 C CG2 . ILE A 1 106 ? 63.880 25.323 14.459 1.00 28.55 ? 107 ILE A CG2 1 ATOM 705 C CD1 . ILE A 1 106 ? 62.192 28.190 15.846 1.00 28.05 ? 107 ILE A CD1 1 ATOM 706 N N . VAL A 1 107 ? 64.343 22.721 16.642 1.00 29.42 ? 108 VAL A N 1 ATOM 707 C CA . VAL A 1 107 ? 65.550 21.906 16.787 1.00 29.29 ? 108 VAL A CA 1 ATOM 708 C C . VAL A 1 107 ? 66.250 21.888 15.431 1.00 32.42 ? 108 VAL A C 1 ATOM 709 O O . VAL A 1 107 ? 65.647 21.526 14.414 1.00 32.05 ? 108 VAL A O 1 ATOM 710 C CB . VAL A 1 107 ? 65.266 20.474 17.339 1.00 32.86 ? 108 VAL A CB 1 ATOM 711 C CG1 . VAL A 1 107 ? 66.493 19.572 17.207 1.00 31.93 ? 108 VAL A CG1 1 ATOM 712 C CG2 . VAL A 1 107 ? 64.789 20.531 18.782 1.00 32.10 ? 108 VAL A CG2 1 ATOM 713 N N . THR A 1 108 ? 67.504 22.321 15.425 1.00 29.56 ? 109 THR A N 1 ATOM 714 C CA . THR A 1 108 ? 68.351 22.344 14.236 1.00 31.40 ? 109 THR A CA 1 ATOM 715 C C . THR A 1 108 ? 69.593 21.477 14.557 1.00 39.70 ? 109 THR A C 1 ATOM 716 O O . THR A 1 108 ? 69.849 21.214 15.736 1.00 38.78 ? 109 THR A O 1 ATOM 717 C CB . THR A 1 108 ? 68.807 23.817 13.902 1.00 36.08 ? 109 THR A CB 1 ATOM 718 O OG1 . THR A 1 108 ? 69.719 24.283 14.893 1.00 35.63 ? 109 THR A OG1 1 ATOM 719 C CG2 . THR A 1 108 ? 67.638 24.791 13.732 1.00 29.74 ? 109 THR A CG2 1 ATOM 720 N N . PRO A 1 109 ? 70.439 21.118 13.565 1.00 40.89 ? 110 PRO A N 1 ATOM 721 C CA . PRO A 1 109 ? 71.669 20.364 13.890 1.00 41.04 ? 110 PRO A CA 1 ATOM 722 C C . PRO A 1 109 ? 72.625 21.090 14.841 1.00 45.18 ? 110 PRO A C 1 ATOM 723 O O . PRO A 1 109 ? 73.369 20.420 15.546 1.00 47.27 ? 110 PRO A O 1 ATOM 724 C CB . PRO A 1 109 ? 72.314 20.147 12.519 1.00 42.75 ? 110 PRO A CB 1 ATOM 725 C CG . PRO A 1 109 ? 71.162 20.197 11.566 1.00 47.66 ? 110 PRO A CG 1 ATOM 726 C CD . PRO A 1 109 ? 70.321 21.316 12.105 1.00 43.35 ? 110 PRO A CD 1 ATOM 727 N N . GLU A 1 110 ? 72.564 22.438 14.918 1.00 39.95 ? 111 GLU A N 1 ATOM 728 C CA . GLU A 1 110 ? 73.437 23.270 15.772 1.00 38.25 ? 111 GLU A CA 1 ATOM 729 C C . GLU A 1 110 ? 72.912 23.475 17.168 1.00 38.43 ? 111 GLU A C 1 ATOM 730 O O . GLU A 1 110 ? 73.678 23.760 18.087 1.00 36.90 ? 111 GLU A O 1 ATOM 731 C CB . GLU A 1 110 ? 73.707 24.646 15.137 1.00 39.84 ? 111 GLU A CB 1 ATOM 732 C CG . GLU A 1 110 ? 74.576 24.613 13.893 1.00 49.36 ? 111 GLU A CG 1 ATOM 733 C CD . GLU A 1 110 ? 73.926 24.009 12.661 1.00 88.20 ? 111 GLU A CD 1 ATOM 734 O OE1 . GLU A 1 110 ? 72.760 24.357 12.348 1.00 76.39 ? 111 GLU A OE1 1 ATOM 735 O OE2 . GLU A 1 110 ? 74.586 23.156 12.025 1.00 99.49 ? 111 GLU A OE2 1 ATOM 736 N N . GLY A 1 111 ? 71.606 23.379 17.327 1.00 34.05 ? 112 GLY A N 1 ATOM 737 C CA . GLY A 1 111 ? 71.008 23.588 18.635 1.00 31.54 ? 112 GLY A CA 1 ATOM 738 C C . GLY A 1 111 ? 69.569 24.024 18.584 1.00 32.05 ? 112 GLY A C 1 ATOM 739 O O . GLY A 1 111 ? 68.836 23.751 17.618 1.00 30.16 ? 112 GLY A O 1 ATOM 740 N N . ASN A 1 112 ? 69.159 24.712 19.638 1.00 28.44 ? 113 ASN A N 1 ATOM 741 C CA . ASN A 1 112 ? 67.758 25.101 19.777 1.00 26.98 ? 113 ASN A CA 1 ATOM 742 C C . ASN A 1 112 ? 67.506 26.583 19.640 1.00 27.06 ? 113 ASN A C 1 ATOM 743 O O . ASN A 1 112 ? 68.208 27.424 20.233 1.00 25.70 ? 113 ASN A O 1 ATOM 744 C CB . ASN A 1 112 ? 67.171 24.585 21.111 1.00 24.78 ? 113 ASN A CB 1 ATOM 745 C CG . ASN A 1 112 ? 67.458 23.138 21.416 1.00 39.82 ? 113 ASN A CG 1 ATOM 746 O OD1 . ASN A 1 112 ? 67.310 22.249 20.580 1.00 34.37 ? 113 ASN A OD1 1 ATOM 747 N ND2 . ASN A 1 112 ? 67.848 22.875 22.637 1.00 36.60 ? 113 ASN A ND2 1 ATOM 748 N N . LEU A 1 113 ? 66.423 26.868 18.936 1.00 22.51 ? 114 LEU A N 1 ATOM 749 C CA . LEU A 1 113 ? 65.901 28.210 18.690 1.00 22.62 ? 114 LEU A CA 1 ATOM 750 C C . LEU A 1 113 ? 64.475 28.275 19.177 1.00 28.26 ? 114 LEU A C 1 ATOM 751 O O . LEU A 1 113 ? 63.836 27.224 19.351 1.00 28.27 ? 114 LEU A O 1 ATOM 752 C CB . LEU A 1 113 ? 65.965 28.568 17.180 1.00 21.80 ? 114 LEU A CB 1 ATOM 753 C CG . LEU A 1 113 ? 67.268 28.233 16.408 1.00 21.93 ? 114 LEU A CG 1 ATOM 754 C CD1 . LEU A 1 113 ? 67.056 28.466 14.953 1.00 21.34 ? 114 LEU A CD1 1 ATOM 755 C CD2 . LEU A 1 113 ? 68.468 29.038 16.935 1.00 18.25 ? 114 LEU A CD2 1 ATOM 756 N N . GLU A 1 114 ? 63.982 29.502 19.453 1.00 25.60 ? 115 GLU A N 1 ATOM 757 C CA . GLU A 1 114 ? 62.582 29.691 19.869 1.00 24.79 ? 115 GLU A CA 1 ATOM 758 C C . GLU A 1 114 ? 61.962 31.042 19.508 1.00 29.25 ? 115 GLU A C 1 ATOM 759 O O . GLU A 1 114 ? 62.632 32.066 19.497 1.00 30.83 ? 115 GLU A O 1 ATOM 760 C CB . GLU A 1 114 ? 62.301 29.329 21.334 1.00 25.17 ? 115 GLU A CB 1 ATOM 761 C CG . GLU A 1 114 ? 62.770 30.344 22.341 1.00 37.84 ? 115 GLU A CG 1 ATOM 762 C CD . GLU A 1 114 ? 62.229 30.166 23.747 1.00 60.61 ? 115 GLU A CD 1 ATOM 763 O OE1 . GLU A 1 114 ? 61.794 29.039 24.090 1.00 42.08 ? 115 GLU A OE1 1 ATOM 764 O OE2 . GLU A 1 114 ? 62.283 31.155 24.519 1.00 48.71 ? 115 GLU A OE2 1 ATOM 765 N N . LYS A 1 115 ? 60.674 31.015 19.257 1.00 23.70 ? 116 LYS A N 1 ATOM 766 C CA . LYS A 1 115 ? 59.835 32.156 19.009 1.00 23.31 ? 116 LYS A CA 1 ATOM 767 C C . LYS A 1 115 ? 58.652 32.054 20.001 1.00 28.79 ? 116 LYS A C 1 ATOM 768 O O . LYS A 1 115 ? 57.975 31.024 20.047 1.00 29.72 ? 116 LYS A O 1 ATOM 769 C CB . LYS A 1 115 ? 59.325 32.150 17.539 1.00 24.11 ? 116 LYS A CB 1 ATOM 770 C CG . LYS A 1 115 ? 58.566 33.422 17.134 1.00 29.66 ? 116 LYS A CG 1 ATOM 771 C CD . LYS A 1 115 ? 59.527 34.621 17.034 1.00 34.50 ? 116 LYS A CD 1 ATOM 772 C CE . LYS A 1 115 ? 58.917 35.806 16.367 1.00 30.73 ? 116 LYS A CE 1 ATOM 773 N NZ . LYS A 1 115 ? 59.739 37.023 16.586 1.00 31.93 ? 116 LYS A NZ 1 ATOM 774 N N . VAL A 1 116 ? 58.413 33.115 20.783 1.00 26.35 ? 117 VAL A N 1 ATOM 775 C CA . VAL A 1 116 ? 57.333 33.161 21.763 1.00 25.94 ? 117 VAL A CA 1 ATOM 776 C C . VAL A 1 116 ? 56.299 34.251 21.386 1.00 31.96 ? 117 VAL A C 1 ATOM 777 O O . VAL A 1 116 ? 56.651 35.391 21.118 1.00 30.67 ? 117 VAL A O 1 ATOM 778 C CB . VAL A 1 116 ? 57.882 33.356 23.219 1.00 29.20 ? 117 VAL A CB 1 ATOM 779 C CG1 . VAL A 1 116 ? 56.761 33.295 24.254 1.00 28.58 ? 117 VAL A CG1 1 ATOM 780 C CG2 . VAL A 1 116 ? 58.973 32.343 23.565 1.00 28.06 ? 117 VAL A CG2 1 ATOM 781 N N . TYR A 1 117 ? 55.027 33.879 21.372 1.00 31.26 ? 118 TYR A N 1 ATOM 782 C CA . TYR A 1 117 ? 53.880 34.775 21.185 1.00 30.31 ? 118 TYR A CA 1 ATOM 783 C C . TYR A 1 117 ? 53.025 34.762 22.437 1.00 34.92 ? 118 TYR A C 1 ATOM 784 O O . TYR A 1 117 ? 52.745 33.712 23.007 1.00 33.46 ? 118 TYR A O 1 ATOM 785 C CB . TYR A 1 117 ? 52.990 34.352 20.003 1.00 29.73 ? 118 TYR A CB 1 ATOM 786 C CG . TYR A 1 117 ? 53.645 34.557 18.662 1.00 31.10 ? 118 TYR A CG 1 ATOM 787 C CD1 . TYR A 1 117 ? 53.564 35.782 18.003 1.00 33.03 ? 118 TYR A CD1 1 ATOM 788 C CD2 . TYR A 1 117 ? 54.366 33.535 18.055 1.00 31.44 ? 118 TYR A CD2 1 ATOM 789 C CE1 . TYR A 1 117 ? 54.179 35.983 16.773 1.00 32.74 ? 118 TYR A CE1 1 ATOM 790 C CE2 . TYR A 1 117 ? 54.988 33.724 16.826 1.00 32.38 ? 118 TYR A CE2 1 ATOM 791 C CZ . TYR A 1 117 ? 54.887 34.949 16.184 1.00 37.71 ? 118 TYR A CZ 1 ATOM 792 O OH . TYR A 1 117 ? 55.464 35.135 14.957 1.00 30.81 ? 118 TYR A OH 1 ATOM 793 N N . ASP A 1 118 ? 52.578 35.944 22.837 1.00 34.96 ? 119 ASP A N 1 ATOM 794 C CA . ASP A 1 118 ? 51.658 36.154 23.933 1.00 34.45 ? 119 ASP A CA 1 ATOM 795 C C . ASP A 1 118 ? 50.381 36.618 23.230 1.00 33.93 ? 119 ASP A C 1 ATOM 796 O O . ASP A 1 118 ? 50.311 37.746 22.761 1.00 32.62 ? 119 ASP A O 1 ATOM 797 C CB . ASP A 1 118 ? 52.234 37.232 24.840 1.00 37.84 ? 119 ASP A CB 1 ATOM 798 C CG . ASP A 1 118 ? 51.598 37.372 26.200 1.00 64.93 ? 119 ASP A CG 1 ATOM 799 O OD1 . ASP A 1 118 ? 50.339 37.359 26.280 1.00 67.71 ? 119 ASP A OD1 1 ATOM 800 O OD2 . ASP A 1 118 ? 52.347 37.592 27.177 1.00 78.11 ? 119 ASP A OD2 1 ATOM 801 N N . LEU A 1 119 ? 49.427 35.709 23.060 1.00 30.88 ? 120 LEU A N 1 ATOM 802 C CA . LEU A 1 119 ? 48.175 35.971 22.364 1.00 33.19 ? 120 LEU A CA 1 ATOM 803 C C . LEU A 1 119 ? 47.053 36.460 23.317 1.00 41.74 ? 120 LEU A C 1 ATOM 804 O O . LEU A 1 119 ? 46.711 35.781 24.289 1.00 42.11 ? 120 LEU A O 1 ATOM 805 C CB . LEU A 1 119 ? 47.755 34.717 21.586 1.00 33.61 ? 120 LEU A CB 1 ATOM 806 C CG . LEU A 1 119 ? 46.696 34.884 20.500 1.00 39.34 ? 120 LEU A CG 1 ATOM 807 C CD1 . LEU A 1 119 ? 46.932 33.955 19.396 1.00 40.14 ? 120 LEU A CD1 1 ATOM 808 C CD2 . LEU A 1 119 ? 45.353 34.498 21.008 1.00 46.05 ? 120 LEU A CD2 1 ATOM 809 N N . GLN A 1 120 ? 46.518 37.665 23.040 1.00 39.18 ? 121 GLN A N 1 ATOM 810 C CA . GLN A 1 120 ? 45.417 38.295 23.781 1.00 38.54 ? 121 GLN A CA 1 ATOM 811 C C . GLN A 1 120 ? 44.198 38.257 22.888 1.00 41.07 ? 121 GLN A C 1 ATOM 812 O O . GLN A 1 120 ? 44.304 38.569 21.698 1.00 38.35 ? 121 GLN A O 1 ATOM 813 C CB . GLN A 1 120 ? 45.733 39.757 24.128 1.00 40.04 ? 121 GLN A CB 1 ATOM 814 C CG . GLN A 1 120 ? 46.894 39.938 25.109 1.00 70.25 ? 121 GLN A CG 1 ATOM 815 C CD . GLN A 1 120 ? 46.468 39.648 26.530 1.00 102.03 ? 121 GLN A CD 1 ATOM 816 O OE1 . GLN A 1 120 ? 45.613 40.338 27.101 1.00 98.29 ? 121 GLN A OE1 1 ATOM 817 N NE2 . GLN A 1 120 ? 47.027 38.595 27.119 1.00 99.27 ? 121 GLN A NE2 1 ATOM 818 N N . VAL A 1 121 ? 43.047 37.849 23.451 1.00 38.84 ? 122 VAL A N 1 ATOM 819 C CA . VAL A 1 121 ? 41.779 37.780 22.720 1.00 38.41 ? 122 VAL A CA 1 ATOM 820 C C . VAL A 1 121 ? 40.928 38.990 23.063 1.00 42.47 ? 122 VAL A C 1 ATOM 821 O O . VAL A 1 121 ? 40.746 39.337 24.237 1.00 41.79 ? 122 VAL A O 1 ATOM 822 C CB . VAL A 1 121 ? 41.026 36.450 22.887 1.00 42.02 ? 122 VAL A CB 1 ATOM 823 C CG1 . VAL A 1 121 ? 39.708 36.463 22.113 1.00 42.16 ? 122 VAL A CG1 1 ATOM 824 C CG2 . VAL A 1 121 ? 41.893 35.283 22.419 1.00 41.13 ? 122 VAL A CG2 1 ATOM 825 N N . LEU A 1 122 ? 40.478 39.683 22.009 1.00 39.02 ? 123 LEU A N 1 ATOM 826 C CA . LEU A 1 122 ? 39.640 40.873 22.141 1.00 36.54 ? 123 LEU A CA 1 ATOM 827 C C . LEU A 1 122 ? 38.223 40.476 21.796 1.00 36.55 ? 123 LEU A C 1 ATOM 828 O O . LEU A 1 122 ? 37.993 39.790 20.795 1.00 37.06 ? 123 LEU A O 1 ATOM 829 C CB . LEU A 1 122 ? 40.126 42.015 21.226 1.00 35.90 ? 123 LEU A CB 1 ATOM 830 C CG . LEU A 1 122 ? 41.598 42.443 21.340 1.00 39.80 ? 123 LEU A CG 1 ATOM 831 C CD1 . LEU A 1 122 ? 41.938 43.460 20.317 1.00 37.40 ? 123 LEU A CD1 1 ATOM 832 C CD2 . LEU A 1 122 ? 41.940 42.955 22.746 1.00 42.81 ? 123 LEU A CD2 1 ATOM 833 N N . VAL A 1 123 ? 37.289 40.863 22.649 1.00 31.76 ? 124 VAL A N 1 ATOM 834 C CA . VAL A 1 123 ? 35.872 40.584 22.461 1.00 32.55 ? 124 VAL A CA 1 ATOM 835 C C . VAL A 1 123 ? 35.130 41.921 22.288 1.00 38.50 ? 124 VAL A C 1 ATOM 836 O O . VAL A 1 123 ? 35.082 42.715 23.230 1.00 38.41 ? 124 VAL A O 1 ATOM 837 C CB . VAL A 1 123 ? 35.261 39.766 23.627 1.00 36.58 ? 124 VAL A CB 1 ATOM 838 C CG1 . VAL A 1 123 ? 33.822 39.372 23.315 1.00 35.64 ? 124 VAL A CG1 1 ATOM 839 C CG2 . VAL A 1 123 ? 36.110 38.532 23.959 1.00 36.16 ? 124 VAL A CG2 1 ATOM 840 N N . PRO A 1 124 ? 34.557 42.193 21.091 1.00 35.38 ? 125 PRO A N 1 ATOM 841 C CA . PRO A 1 124 ? 33.789 43.445 20.913 1.00 34.49 ? 125 PRO A CA 1 ATOM 842 C C . PRO A 1 124 ? 32.530 43.437 21.781 1.00 35.93 ? 125 PRO A C 1 ATOM 843 O O . PRO A 1 124 ? 31.846 42.404 21.835 1.00 36.45 ? 125 PRO A O 1 ATOM 844 C CB . PRO A 1 124 ? 33.396 43.427 19.421 1.00 36.47 ? 125 PRO A CB 1 ATOM 845 C CG . PRO A 1 124 ? 34.250 42.383 18.791 1.00 41.76 ? 125 PRO A CG 1 ATOM 846 C CD . PRO A 1 124 ? 34.545 41.371 19.859 1.00 37.38 ? 125 PRO A CD 1 ATOM 847 N N . PRO A 1 125 ? 32.188 44.536 22.488 1.00 30.01 ? 126 PRO A N 1 ATOM 848 C CA . PRO A 1 125 ? 30.961 44.504 23.285 1.00 29.61 ? 126 PRO A CA 1 ATOM 849 C C . PRO A 1 125 ? 29.705 44.509 22.412 1.00 37.04 ? 126 PRO A C 1 ATOM 850 O O . PRO A 1 125 ? 29.743 45.001 21.273 1.00 37.59 ? 126 PRO A O 1 ATOM 851 C CB . PRO A 1 125 ? 31.068 45.770 24.139 1.00 30.68 ? 126 PRO A CB 1 ATOM 852 C CG . PRO A 1 125 ? 31.914 46.686 23.363 1.00 35.08 ? 126 PRO A CG 1 ATOM 853 C CD . PRO A 1 125 ? 32.845 45.863 22.541 1.00 30.65 ? 126 PRO A CD 1 ATOM 854 N N . GLU A 1 126 ? 28.605 43.928 22.914 1.00 36.16 ? 127 GLU A N 1 ATOM 855 C CA . GLU A 1 126 ? 27.301 43.949 22.216 1.00 36.35 ? 127 GLU A CA 1 ATOM 856 C C . GLU A 1 126 ? 26.565 45.116 22.844 1.00 39.77 ? 127 GLU A C 1 ATOM 857 O O . GLU A 1 126 ? 26.404 45.147 24.066 1.00 36.72 ? 127 GLU A O 1 ATOM 858 C CB . GLU A 1 126 ? 26.528 42.660 22.416 1.00 37.43 ? 127 GLU A CB 1 ATOM 859 C CG . GLU A 1 126 ? 27.022 41.525 21.540 1.00 45.48 ? 127 GLU A CG 1 ATOM 860 C CD . GLU A 1 126 ? 26.256 40.217 21.639 1.00 63.19 ? 127 GLU A CD 1 ATOM 861 O OE1 . GLU A 1 126 ? 25.419 40.057 22.557 1.00 50.31 ? 127 GLU A OE1 1 ATOM 862 O OE2 . GLU A 1 126 ? 26.517 39.331 20.796 1.00 66.60 ? 127 GLU A OE2 1 ATOM 863 N N . VAL A 1 127 ? 26.257 46.146 22.032 1.00 37.77 ? 128 VAL A N 1 ATOM 864 C CA . VAL A 1 127 ? 25.659 47.374 22.558 1.00 36.89 ? 128 VAL A CA 1 ATOM 865 C C . VAL A 1 127 ? 24.155 47.451 22.418 1.00 39.40 ? 128 VAL A C 1 ATOM 866 O O . VAL A 1 127 ? 23.550 46.845 21.539 1.00 37.86 ? 128 VAL A O 1 ATOM 867 C CB . VAL A 1 127 ? 26.352 48.671 22.070 1.00 40.52 ? 128 VAL A CB 1 ATOM 868 C CG1 . VAL A 1 127 ? 27.860 48.622 22.311 1.00 40.87 ? 128 VAL A CG1 1 ATOM 869 C CG2 . VAL A 1 127 ? 26.061 48.903 20.596 1.00 40.80 ? 128 VAL A CG2 1 ATOM 870 N N . THR A 1 128 ? 23.572 48.242 23.293 1.00 36.24 ? 129 THR A N 1 ATOM 871 C CA . THR A 1 128 ? 22.167 48.569 23.321 1.00 35.67 ? 129 THR A CA 1 ATOM 872 C C . THR A 1 128 ? 21.994 49.962 23.890 1.00 37.22 ? 129 THR A C 1 ATOM 873 O O . THR A 1 128 ? 22.798 50.426 24.696 1.00 35.91 ? 129 THR A O 1 ATOM 874 C CB . THR A 1 128 ? 21.302 47.468 23.932 1.00 51.20 ? 129 THR A CB 1 ATOM 875 O OG1 . THR A 1 128 ? 19.965 47.729 23.510 1.00 60.45 ? 129 THR A OG1 1 ATOM 876 C CG2 . THR A 1 128 ? 21.391 47.415 25.454 1.00 46.06 ? 129 THR A CG2 1 ATOM 877 N N . TYR A 1 129 ? 20.978 50.650 23.401 1.00 34.58 ? 130 TYR A N 1 ATOM 878 C CA . TYR A 1 129 ? 20.663 52.018 23.772 1.00 34.13 ? 130 TYR A CA 1 ATOM 879 C C . TYR A 1 129 ? 19.156 52.134 23.914 1.00 41.24 ? 130 TYR A C 1 ATOM 880 O O . TYR A 1 129 ? 18.420 51.580 23.102 1.00 38.74 ? 130 TYR A O 1 ATOM 881 C CB . TYR A 1 129 ? 21.090 52.988 22.659 1.00 34.02 ? 130 TYR A CB 1 ATOM 882 C CG . TYR A 1 129 ? 22.462 52.765 22.055 1.00 31.48 ? 130 TYR A CG 1 ATOM 883 C CD1 . TYR A 1 129 ? 22.652 51.850 21.022 1.00 30.79 ? 130 TYR A CD1 1 ATOM 884 C CD2 . TYR A 1 129 ? 23.548 53.529 22.455 1.00 32.07 ? 130 TYR A CD2 1 ATOM 885 C CE1 . TYR A 1 129 ? 23.894 51.686 20.421 1.00 30.80 ? 130 TYR A CE1 1 ATOM 886 C CE2 . TYR A 1 129 ? 24.800 53.373 21.865 1.00 32.13 ? 130 TYR A CE2 1 ATOM 887 C CZ . TYR A 1 129 ? 24.966 52.455 20.844 1.00 37.42 ? 130 TYR A CZ 1 ATOM 888 O OH . TYR A 1 129 ? 26.182 52.326 20.242 1.00 36.20 ? 130 TYR A OH 1 ATOM 889 N N . PHE A 1 130 ? 18.691 52.899 24.913 1.00 40.95 ? 131 PHE A N 1 ATOM 890 C CA . PHE A 1 130 ? 17.265 53.113 25.057 1.00 40.92 ? 131 PHE A CA 1 ATOM 891 C C . PHE A 1 130 ? 16.901 54.244 25.941 1.00 45.90 ? 131 PHE A C 1 ATOM 892 O O . PHE A 1 130 ? 17.592 54.474 26.915 1.00 45.33 ? 131 PHE A O 1 ATOM 893 C CB . PHE A 1 130 ? 16.523 51.843 25.468 1.00 43.19 ? 131 PHE A CB 1 ATOM 894 C CG . PHE A 1 130 ? 17.010 51.103 26.683 1.00 44.47 ? 131 PHE A CG 1 ATOM 895 C CD1 . PHE A 1 130 ? 17.970 50.107 26.566 1.00 45.55 ? 131 PHE A CD1 1 ATOM 896 C CD2 . PHE A 1 130 ? 16.425 51.321 27.932 1.00 47.48 ? 131 PHE A CD2 1 ATOM 897 C CE1 . PHE A 1 130 ? 18.398 49.397 27.691 1.00 48.31 ? 131 PHE A CE1 1 ATOM 898 C CE2 . PHE A 1 130 ? 16.823 50.583 29.051 1.00 47.80 ? 131 PHE A CE2 1 ATOM 899 C CZ . PHE A 1 130 ? 17.802 49.622 28.922 1.00 46.57 ? 131 PHE A CZ 1 ATOM 900 N N . PRO A 1 131 ? 15.799 54.976 25.650 1.00 45.43 ? 132 PRO A N 1 ATOM 901 C CA . PRO A 1 131 ? 15.365 56.020 26.599 1.00 45.48 ? 132 PRO A CA 1 ATOM 902 C C . PRO A 1 131 ? 14.665 55.356 27.780 1.00 51.28 ? 132 PRO A C 1 ATOM 903 O O . PRO A 1 131 ? 14.161 54.242 27.678 1.00 49.91 ? 132 PRO A O 1 ATOM 904 C CB . PRO A 1 131 ? 14.396 56.883 25.785 1.00 46.58 ? 132 PRO A CB 1 ATOM 905 C CG . PRO A 1 131 ? 14.120 56.137 24.524 1.00 50.16 ? 132 PRO A CG 1 ATOM 906 C CD . PRO A 1 131 ? 14.847 54.836 24.523 1.00 46.02 ? 132 PRO A CD 1 ATOM 907 N N . GLY A 1 132 ? 14.691 56.021 28.912 1.00 51.18 ? 133 GLY A N 1 ATOM 908 C CA . GLY A 1 132 ? 14.033 55.532 30.115 1.00 52.00 ? 133 GLY A CA 1 ATOM 909 C C . GLY A 1 132 ? 12.972 56.519 30.553 1.00 59.08 ? 133 GLY A C 1 ATOM 910 O O . GLY A 1 132 ? 12.708 57.499 29.841 1.00 58.60 ? 133 GLY A O 1 ATOM 911 N N . LYS A 1 133 ? 12.358 56.285 31.726 1.00 58.57 ? 134 LYS A N 1 ATOM 912 C CA . LYS A 1 133 ? 11.332 57.195 32.221 1.00 60.14 ? 134 LYS A CA 1 ATOM 913 C C . LYS A 1 133 ? 11.963 58.439 32.812 1.00 66.22 ? 134 LYS A C 1 ATOM 914 O O . LYS A 1 133 ? 13.072 58.375 33.338 1.00 66.92 ? 134 LYS A O 1 ATOM 915 C CB . LYS A 1 133 ? 10.385 56.494 33.226 1.00 64.26 ? 134 LYS A CB 1 ATOM 916 C CG . LYS A 1 133 ? 9.629 55.283 32.641 1.00 85.32 ? 134 LYS A CG 1 ATOM 917 C CD . LYS A 1 133 ? 8.092 55.273 32.869 1.00 100.48 ? 134 LYS A CD 1 ATOM 918 C CE . LYS A 1 133 ? 7.398 54.163 32.099 1.00 111.07 ? 134 LYS A CE 1 ATOM 919 N NZ . LYS A 1 133 ? 6.093 54.602 31.528 1.00 119.60 ? 134 LYS A NZ 1 ATOM 920 N N . ASN A 1 134 ? 11.274 59.577 32.690 1.00 63.98 ? 135 ASN A N 1 ATOM 921 C CA . ASN A 1 134 ? 11.663 60.878 33.254 1.00 63.46 ? 135 ASN A CA 1 ATOM 922 C C . ASN A 1 134 ? 12.997 61.407 32.751 1.00 62.39 ? 135 ASN A C 1 ATOM 923 O O . ASN A 1 134 ? 13.898 61.726 33.536 1.00 61.87 ? 135 ASN A O 1 ATOM 924 C CB . ASN A 1 134 ? 11.530 60.901 34.820 1.00 71.13 ? 135 ASN A CB 1 ATOM 925 C CG . ASN A 1 134 ? 11.605 62.268 35.505 1.00 107.74 ? 135 ASN A CG 1 ATOM 926 O OD1 . ASN A 1 134 ? 11.452 63.336 34.890 1.00 99.90 ? 135 ASN A OD1 1 ATOM 927 N ND2 . ASN A 1 134 ? 11.831 62.258 36.818 1.00 102.96 ? 135 ASN A ND2 1 ATOM 928 N N . ARG A 1 135 ? 13.102 61.512 31.423 1.00 55.74 ? 136 ARG A N 1 ATOM 929 C CA . ARG A 1 135 ? 14.247 62.087 30.730 1.00 54.20 ? 136 ARG A CA 1 ATOM 930 C C . ARG A 1 135 ? 15.626 61.439 31.065 1.00 54.94 ? 136 ARG A C 1 ATOM 931 O O . ARG A 1 135 ? 16.653 62.118 31.199 1.00 53.19 ? 136 ARG A O 1 ATOM 932 C CB . ARG A 1 135 ? 14.219 63.625 30.838 1.00 54.39 ? 136 ARG A CB 1 ATOM 933 C CG . ARG A 1 135 ? 13.200 64.277 29.897 1.00 67.28 ? 136 ARG A CG 1 ATOM 934 C CD . ARG A 1 135 ? 13.279 65.802 29.854 1.00 80.45 ? 136 ARG A CD 1 ATOM 935 N NE . ARG A 1 135 ? 14.456 66.313 29.140 1.00 88.04 ? 136 ARG A NE 1 ATOM 936 C CZ . ARG A 1 135 ? 15.479 66.928 29.728 1.00 101.08 ? 136 ARG A CZ 1 ATOM 937 N NH1 . ARG A 1 135 ? 15.477 67.133 31.042 1.00 90.08 ? 136 ARG A NH1 1 ATOM 938 N NH2 . ARG A 1 135 ? 16.509 67.346 29.010 1.00 81.83 ? 136 ARG A NH2 1 ATOM 939 N N . THR A 1 136 ? 15.617 60.100 31.176 1.00 48.73 ? 137 THR A N 1 ATOM 940 C CA . THR A 1 136 ? 16.792 59.283 31.396 1.00 47.23 ? 137 THR A CA 1 ATOM 941 C C . THR A 1 136 ? 17.121 58.502 30.116 1.00 49.66 ? 137 THR A C 1 ATOM 942 O O . THR A 1 136 ? 16.258 58.322 29.250 1.00 49.64 ? 137 THR A O 1 ATOM 943 C CB . THR A 1 136 ? 16.626 58.355 32.616 1.00 49.62 ? 137 THR A CB 1 ATOM 944 O OG1 . THR A 1 136 ? 15.639 57.365 32.354 1.00 48.37 ? 137 THR A OG1 1 ATOM 945 C CG2 . THR A 1 136 ? 16.346 59.107 33.911 1.00 43.19 ? 137 THR A CG2 1 ATOM 946 N N . ALA A 1 137 ? 18.370 58.045 29.993 1.00 43.20 ? 138 ALA A N 1 ATOM 947 C CA . ALA A 1 137 ? 18.790 57.244 28.848 1.00 40.38 ? 138 ALA A CA 1 ATOM 948 C C . ALA A 1 137 ? 19.725 56.184 29.382 1.00 39.79 ? 138 ALA A C 1 ATOM 949 O O . ALA A 1 137 ? 20.391 56.402 30.384 1.00 36.38 ? 138 ALA A O 1 ATOM 950 C CB . ALA A 1 137 ? 19.475 58.117 27.806 1.00 40.41 ? 138 ALA A CB 1 ATOM 951 N N . VAL A 1 138 ? 19.722 55.009 28.748 1.00 36.44 ? 139 VAL A N 1 ATOM 952 C CA . VAL A 1 138 ? 20.535 53.868 29.123 1.00 35.24 ? 139 VAL A CA 1 ATOM 953 C C . VAL A 1 138 ? 21.400 53.461 27.937 1.00 38.28 ? 139 VAL A C 1 ATOM 954 O O . VAL A 1 138 ? 20.936 53.406 26.795 1.00 35.91 ? 139 VAL A O 1 ATOM 955 C CB . VAL A 1 138 ? 19.689 52.681 29.678 1.00 39.37 ? 139 VAL A CB 1 ATOM 956 C CG1 . VAL A 1 138 ? 20.562 51.499 30.117 1.00 38.49 ? 139 VAL A CG1 1 ATOM 957 C CG2 . VAL A 1 138 ? 18.812 53.133 30.831 1.00 40.05 ? 139 VAL A CG2 1 ATOM 958 N N . CYS A 1 139 ? 22.670 53.175 28.233 1.00 36.15 ? 140 CYS A N 1 ATOM 959 C CA . CYS A 1 139 ? 23.664 52.694 27.277 1.00 35.24 ? 140 CYS A CA 1 ATOM 960 C C . CYS A 1 139 ? 24.353 51.512 27.910 1.00 37.91 ? 140 CYS A C 1 ATOM 961 O O . CYS A 1 139 ? 24.843 51.623 29.036 1.00 36.41 ? 140 CYS A O 1 ATOM 962 C CB . CYS A 1 139 ? 24.659 53.792 26.944 1.00 35.20 ? 140 CYS A CB 1 ATOM 963 S SG . CYS A 1 139 ? 25.584 53.495 25.428 1.00 39.70 ? 140 CYS A SG 1 ATOM 964 N N . GLU A 1 140 ? 24.366 50.375 27.216 1.00 33.70 ? 141 GLU A N 1 ATOM 965 C CA . GLU A 1 140 ? 24.985 49.171 27.726 1.00 33.61 ? 141 GLU A CA 1 ATOM 966 C C . GLU A 1 140 ? 25.933 48.600 26.712 1.00 40.07 ? 141 GLU A C 1 ATOM 967 O O . GLU A 1 140 ? 25.614 48.571 25.530 1.00 38.13 ? 141 GLU A O 1 ATOM 968 C CB . GLU A 1 140 ? 23.948 48.100 28.113 1.00 34.96 ? 141 GLU A CB 1 ATOM 969 C CG . GLU A 1 140 ? 22.887 48.578 29.096 1.00 46.74 ? 141 GLU A CG 1 ATOM 970 C CD . GLU A 1 140 ? 21.766 47.626 29.477 1.00 65.70 ? 141 GLU A CD 1 ATOM 971 O OE1 . GLU A 1 140 ? 21.401 46.751 28.661 1.00 66.79 ? 141 GLU A OE1 1 ATOM 972 O OE2 . GLU A 1 140 ? 21.252 47.758 30.611 1.00 59.38 ? 141 GLU A OE2 1 ATOM 973 N N . ALA A 1 141 ? 27.088 48.094 27.198 1.00 37.95 ? 142 ALA A N 1 ATOM 974 C CA . ALA A 1 141 ? 28.125 47.451 26.414 1.00 36.55 ? 142 ALA A CA 1 ATOM 975 C C . ALA A 1 141 ? 28.343 46.091 27.093 1.00 41.88 ? 142 ALA A C 1 ATOM 976 O O . ALA A 1 141 ? 29.045 45.995 28.091 1.00 43.11 ? 142 ALA A O 1 ATOM 977 C CB . ALA A 1 141 ? 29.391 48.297 26.456 1.00 36.71 ? 142 ALA A CB 1 ATOM 978 N N . MET A 1 142 ? 27.683 45.064 26.575 1.00 37.68 ? 143 MET A N 1 ATOM 979 C CA . MET A 1 142 ? 27.654 43.711 27.084 1.00 37.96 ? 143 MET A CA 1 ATOM 980 C C . MET A 1 142 ? 28.841 42.848 26.736 1.00 42.67 ? 143 MET A C 1 ATOM 981 O O . MET A 1 142 ? 29.143 42.646 25.555 1.00 42.88 ? 143 MET A O 1 ATOM 982 C CB . MET A 1 142 ? 26.369 43.006 26.606 1.00 41.05 ? 143 MET A CB 1 ATOM 983 C CG . MET A 1 142 ? 25.383 42.722 27.706 1.00 46.95 ? 143 MET A CG 1 ATOM 984 S SD . MET A 1 142 ? 24.667 44.219 28.404 1.00 53.65 ? 143 MET A SD 1 ATOM 985 C CE . MET A 1 142 ? 23.288 44.409 27.326 1.00 51.37 ? 143 MET A CE 1 ATOM 986 N N . ALA A 1 143 ? 29.449 42.238 27.788 1.00 37.51 ? 144 ALA A N 1 ATOM 987 C CA . ALA A 1 143 ? 30.529 41.259 27.711 1.00 34.71 ? 144 ALA A CA 1 ATOM 988 C C . ALA A 1 143 ? 31.658 41.586 26.705 1.00 38.08 ? 144 ALA A C 1 ATOM 989 O O . ALA A 1 143 ? 31.915 40.837 25.769 1.00 37.89 ? 144 ALA A O 1 ATOM 990 C CB . ALA A 1 143 ? 29.944 39.861 27.475 1.00 34.40 ? 144 ALA A CB 1 ATOM 991 N N . GLY A 1 144 ? 32.328 42.704 26.935 1.00 35.64 ? 145 GLY A N 1 ATOM 992 C CA . GLY A 1 144 ? 33.463 43.133 26.131 1.00 35.26 ? 145 GLY A CA 1 ATOM 993 C C . GLY A 1 144 ? 34.788 42.806 26.804 1.00 38.31 ? 145 GLY A C 1 ATOM 994 O O . GLY A 1 144 ? 34.859 42.726 28.037 1.00 38.29 ? 145 GLY A O 1 ATOM 995 N N . LYS A 1 145 ? 35.845 42.619 25.998 1.00 34.26 ? 146 LYS A N 1 ATOM 996 C CA . LYS A 1 145 ? 37.185 42.356 26.507 1.00 33.74 ? 146 LYS A CA 1 ATOM 997 C C . LYS A 1 145 ? 38.199 43.143 25.671 1.00 35.59 ? 146 LYS A C 1 ATOM 998 O O . LYS A 1 145 ? 38.380 42.837 24.501 1.00 34.55 ? 146 LYS A O 1 ATOM 999 C CB . LYS A 1 145 ? 37.521 40.849 26.514 1.00 36.78 ? 146 LYS A CB 1 ATOM 1000 C CG . LYS A 1 145 ? 38.770 40.520 27.306 1.00 38.95 ? 146 LYS A CG 1 ATOM 1001 C CD . LYS A 1 145 ? 39.166 39.047 27.211 1.00 45.46 ? 146 LYS A CD 1 ATOM 1002 C CE . LYS A 1 145 ? 40.563 38.805 27.779 1.00 37.89 ? 146 LYS A CE 1 ATOM 1003 N NZ . LYS A 1 145 ? 41.640 39.373 26.897 1.00 40.35 ? 146 LYS A NZ 1 ATOM 1004 N N . PRO A 1 146 ? 38.862 44.160 26.244 1.00 30.17 ? 147 PRO A N 1 ATOM 1005 C CA . PRO A 1 146 ? 38.715 44.684 27.630 1.00 28.78 ? 147 PRO A CA 1 ATOM 1006 C C . PRO A 1 146 ? 37.368 45.381 27.834 1.00 35.86 ? 147 PRO A C 1 ATOM 1007 O O . PRO A 1 146 ? 36.557 45.430 26.904 1.00 36.32 ? 147 PRO A O 1 ATOM 1008 C CB . PRO A 1 146 ? 39.894 45.661 27.764 1.00 28.17 ? 147 PRO A CB 1 ATOM 1009 C CG . PRO A 1 146 ? 40.244 46.061 26.404 1.00 33.04 ? 147 PRO A CG 1 ATOM 1010 C CD . PRO A 1 146 ? 39.874 44.909 25.488 1.00 29.87 ? 147 PRO A CD 1 ATOM 1011 N N . ALA A 1 147 ? 37.126 45.928 29.037 1.00 32.49 ? 148 ALA A N 1 ATOM 1012 C CA . ALA A 1 147 ? 35.901 46.656 29.303 1.00 32.20 ? 148 ALA A CA 1 ATOM 1013 C C . ALA A 1 147 ? 35.803 47.853 28.341 1.00 39.43 ? 148 ALA A C 1 ATOM 1014 O O . ALA A 1 147 ? 36.788 48.548 28.125 1.00 39.04 ? 148 ALA A O 1 ATOM 1015 C CB . ALA A 1 147 ? 35.894 47.159 30.722 1.00 31.93 ? 148 ALA A CB 1 ATOM 1016 N N . ALA A 1 148 ? 34.610 48.084 27.764 1.00 35.88 ? 149 ALA A N 1 ATOM 1017 C CA . ALA A 1 148 ? 34.363 49.236 26.923 1.00 34.06 ? 149 ALA A CA 1 ATOM 1018 C C . ALA A 1 148 ? 34.247 50.443 27.836 1.00 35.82 ? 149 ALA A C 1 ATOM 1019 O O . ALA A 1 148 ? 34.034 50.290 29.041 1.00 33.31 ? 149 ALA A O 1 ATOM 1020 C CB . ALA A 1 148 ? 33.060 49.043 26.178 1.00 34.72 ? 149 ALA A CB 1 ATOM 1021 N N . GLN A 1 149 ? 34.428 51.647 27.279 1.00 33.50 ? 150 GLN A N 1 ATOM 1022 C CA . GLN A 1 149 ? 34.237 52.866 28.052 1.00 33.50 ? 150 GLN A CA 1 ATOM 1023 C C . GLN A 1 149 ? 33.044 53.595 27.468 1.00 37.33 ? 150 GLN A C 1 ATOM 1024 O O . GLN A 1 149 ? 32.950 53.761 26.248 1.00 37.04 ? 150 GLN A O 1 ATOM 1025 C CB . GLN A 1 149 ? 35.469 53.770 28.061 1.00 35.01 ? 150 GLN A CB 1 ATOM 1026 C CG . GLN A 1 149 ? 36.603 53.239 28.882 1.00 55.68 ? 150 GLN A CG 1 ATOM 1027 C CD . GLN A 1 149 ? 37.780 54.159 28.763 1.00 79.89 ? 150 GLN A CD 1 ATOM 1028 O OE1 . GLN A 1 149 ? 38.374 54.302 27.689 1.00 79.88 ? 150 GLN A OE1 1 ATOM 1029 N NE2 . GLN A 1 149 ? 38.150 54.809 29.866 1.00 70.58 ? 150 GLN A NE2 1 ATOM 1030 N N . ILE A 1 150 ? 32.139 54.014 28.353 1.00 34.97 ? 151 ILE A N 1 ATOM 1031 C CA . ILE A 1 150 ? 30.923 54.706 27.987 1.00 34.83 ? 151 ILE A CA 1 ATOM 1032 C C . ILE A 1 150 ? 31.032 56.176 28.312 1.00 38.67 ? 151 ILE A C 1 ATOM 1033 O O . ILE A 1 150 ? 31.347 56.536 29.439 1.00 39.84 ? 151 ILE A O 1 ATOM 1034 C CB . ILE A 1 150 ? 29.651 54.022 28.595 1.00 36.95 ? 151 ILE A CB 1 ATOM 1035 C CG1 . ILE A 1 150 ? 29.393 52.657 27.922 1.00 34.98 ? 151 ILE A CG1 1 ATOM 1036 C CG2 . ILE A 1 150 ? 28.447 54.940 28.444 1.00 37.94 ? 151 ILE A CG2 1 ATOM 1037 C CD1 . ILE A 1 150 ? 28.272 51.812 28.484 1.00 33.69 ? 151 ILE A CD1 1 ATOM 1038 N N . SER A 1 151 ? 30.777 57.029 27.318 1.00 33.95 ? 152 SER A N 1 ATOM 1039 C CA . SER A 1 151 ? 30.758 58.469 27.518 1.00 32.76 ? 152 SER A CA 1 ATOM 1040 C C . SER A 1 151 ? 29.534 59.055 26.850 1.00 38.81 ? 152 SER A C 1 ATOM 1041 O O . SER A 1 151 ? 29.071 58.565 25.807 1.00 39.23 ? 152 SER A O 1 ATOM 1042 C CB . SER A 1 151 ? 32.055 59.129 27.059 1.00 34.87 ? 152 SER A CB 1 ATOM 1043 O OG . SER A 1 151 ? 32.328 58.870 25.697 1.00 43.32 ? 152 SER A OG 1 ATOM 1044 N N . TRP A 1 152 ? 28.969 60.069 27.497 1.00 36.73 ? 153 TRP A N 1 ATOM 1045 C CA . TRP A 1 152 ? 27.756 60.741 27.037 1.00 36.71 ? 153 TRP A CA 1 ATOM 1046 C C . TRP A 1 152 ? 27.977 62.159 26.544 1.00 42.20 ? 153 TRP A C 1 ATOM 1047 O O . TRP A 1 152 ? 28.824 62.869 27.092 1.00 40.36 ? 153 TRP A O 1 ATOM 1048 C CB . TRP A 1 152 ? 26.736 60.782 28.172 1.00 34.40 ? 153 TRP A CB 1 ATOM 1049 C CG . TRP A 1 152 ? 26.206 59.449 28.587 1.00 35.11 ? 153 TRP A CG 1 ATOM 1050 C CD1 . TRP A 1 152 ? 26.664 58.663 29.604 1.00 37.60 ? 153 TRP A CD1 1 ATOM 1051 C CD2 . TRP A 1 152 ? 25.055 58.782 28.048 1.00 35.03 ? 153 TRP A CD2 1 ATOM 1052 N NE1 . TRP A 1 152 ? 25.897 57.527 29.707 1.00 36.51 ? 153 TRP A NE1 1 ATOM 1053 C CE2 . TRP A 1 152 ? 24.885 57.588 28.782 1.00 38.26 ? 153 TRP A CE2 1 ATOM 1054 C CE3 . TRP A 1 152 ? 24.157 59.073 26.996 1.00 35.99 ? 153 TRP A CE3 1 ATOM 1055 C CZ2 . TRP A 1 152 ? 23.822 56.716 28.546 1.00 37.41 ? 153 TRP A CZ2 1 ATOM 1056 C CZ3 . TRP A 1 152 ? 23.130 58.185 26.738 1.00 37.00 ? 153 TRP A CZ3 1 ATOM 1057 C CH2 . TRP A 1 152 ? 22.975 57.019 27.500 1.00 37.63 ? 153 TRP A CH2 1 ATOM 1058 N N . THR A 1 153 ? 27.159 62.592 25.559 1.00 42.16 ? 154 THR A N 1 ATOM 1059 C CA . THR A 1 153 ? 27.123 63.971 25.048 1.00 43.54 ? 154 THR A CA 1 ATOM 1060 C C . THR A 1 153 ? 25.662 64.434 25.019 1.00 50.55 ? 154 THR A C 1 ATOM 1061 O O . THR A 1 153 ? 24.850 63.783 24.354 1.00 51.43 ? 154 THR A O 1 ATOM 1062 C CB . THR A 1 153 ? 27.775 64.115 23.681 1.00 52.59 ? 154 THR A CB 1 ATOM 1063 O OG1 . THR A 1 153 ? 29.077 63.534 23.726 1.00 56.07 ? 154 THR A OG1 1 ATOM 1064 C CG2 . THR A 1 153 ? 27.880 65.561 23.258 1.00 48.75 ? 154 THR A CG2 1 ATOM 1065 N N . PRO A 1 154 ? 25.290 65.539 25.702 1.00 46.98 ? 155 PRO A N 1 ATOM 1066 C CA . PRO A 1 154 ? 26.112 66.387 26.584 1.00 47.08 ? 155 PRO A CA 1 ATOM 1067 C C . PRO A 1 154 ? 26.347 65.718 27.950 1.00 54.12 ? 155 PRO A C 1 ATOM 1068 O O . PRO A 1 154 ? 25.892 64.607 28.153 1.00 52.84 ? 155 PRO A O 1 ATOM 1069 C CB . PRO A 1 154 ? 25.260 67.651 26.726 1.00 48.14 ? 155 PRO A CB 1 ATOM 1070 C CG . PRO A 1 154 ? 23.850 67.139 26.668 1.00 51.91 ? 155 PRO A CG 1 ATOM 1071 C CD . PRO A 1 154 ? 23.881 65.988 25.686 1.00 47.71 ? 155 PRO A CD 1 ATOM 1072 N N . ASP A 1 155 ? 27.044 66.385 28.879 1.00 54.98 ? 156 ASP A N 1 ATOM 1073 C CA . ASP A 1 155 ? 27.337 65.850 30.207 1.00 56.48 ? 156 ASP A CA 1 ATOM 1074 C C . ASP A 1 155 ? 26.062 65.702 31.002 1.00 59.07 ? 156 ASP A C 1 ATOM 1075 O O . ASP A 1 155 ? 25.279 66.660 31.115 1.00 60.23 ? 156 ASP A O 1 ATOM 1076 C CB . ASP A 1 155 ? 28.297 66.775 31.004 1.00 60.50 ? 156 ASP A CB 1 ATOM 1077 C CG . ASP A 1 155 ? 29.644 67.103 30.376 1.00 81.06 ? 156 ASP A CG 1 ATOM 1078 O OD1 . ASP A 1 155 ? 30.206 66.226 29.676 1.00 84.01 ? 156 ASP A OD1 1 ATOM 1079 O OD2 . ASP A 1 155 ? 30.171 68.214 30.646 1.00 89.00 ? 156 ASP A OD2 1 ATOM 1080 N N . GLY A 1 156 ? 25.896 64.530 31.604 1.00 52.40 ? 157 GLY A N 1 ATOM 1081 C CA . GLY A 1 156 ? 24.753 64.254 32.456 1.00 50.76 ? 157 GLY A CA 1 ATOM 1082 C C . GLY A 1 156 ? 25.184 63.799 33.826 1.00 53.25 ? 157 GLY A C 1 ATOM 1083 O O . GLY A 1 156 ? 26.383 63.721 34.120 1.00 55.93 ? 157 GLY A O 1 ATOM 1084 N N . ASP A 1 157 ? 24.210 63.518 34.674 1.00 46.52 ? 158 ASP A N 1 ATOM 1085 C CA . ASP A 1 157 ? 24.425 62.972 35.998 1.00 45.52 ? 158 ASP A CA 1 ATOM 1086 C C . ASP A 1 157 ? 24.158 61.477 35.812 1.00 49.50 ? 158 ASP A C 1 ATOM 1087 O O . ASP A 1 157 ? 23.014 61.057 35.625 1.00 48.74 ? 158 ASP A O 1 ATOM 1088 C CB . ASP A 1 157 ? 23.511 63.656 37.021 1.00 46.64 ? 158 ASP A CB 1 ATOM 1089 C CG . ASP A 1 157 ? 23.728 65.161 37.065 1.00 60.19 ? 158 ASP A CG 1 ATOM 1090 O OD1 . ASP A 1 157 ? 24.870 65.585 37.246 1.00 57.93 ? 158 ASP A OD1 1 ATOM 1091 O OD2 . ASP A 1 157 ? 22.758 65.908 36.839 1.00 79.76 ? 158 ASP A OD2 1 ATOM 1092 N N . CYS A 1 158 ? 25.250 60.704 35.725 1.00 46.62 ? 159 CYS A N 1 ATOM 1093 C CA . CYS A 1 158 ? 25.268 59.282 35.379 1.00 46.89 ? 159 CYS A CA 1 ATOM 1094 C C . CYS A 1 158 ? 25.661 58.368 36.490 1.00 44.32 ? 159 CYS A C 1 ATOM 1095 O O . CYS A 1 158 ? 26.339 58.770 37.421 1.00 43.26 ? 159 CYS A O 1 ATOM 1096 C CB . CYS A 1 158 ? 26.160 59.058 34.163 1.00 49.66 ? 159 CYS A CB 1 ATOM 1097 S SG . CYS A 1 158 ? 25.848 60.222 32.806 1.00 55.81 ? 159 CYS A SG 1 ATOM 1098 N N . VAL A 1 159 ? 25.213 57.122 36.388 1.00 38.19 ? 160 VAL A N 1 ATOM 1099 C CA . VAL A 1 159 ? 25.588 56.013 37.251 1.00 37.17 ? 160 VAL A CA 1 ATOM 1100 C C . VAL A 1 159 ? 26.038 54.908 36.299 1.00 40.92 ? 160 VAL A C 1 ATOM 1101 O O . VAL A 1 159 ? 25.240 54.440 35.487 1.00 43.24 ? 160 VAL A O 1 ATOM 1102 C CB . VAL A 1 159 ? 24.497 55.578 38.251 1.00 40.22 ? 160 VAL A CB 1 ATOM 1103 C CG1 . VAL A 1 159 ? 24.942 54.356 39.049 1.00 39.89 ? 160 VAL A CG1 1 ATOM 1104 C CG2 . VAL A 1 159 ? 24.149 56.725 39.197 1.00 39.75 ? 160 VAL A CG2 1 ATOM 1105 N N . THR A 1 160 ? 27.332 54.561 36.329 1.00 35.35 ? 161 THR A N 1 ATOM 1106 C CA . THR A 1 160 ? 27.888 53.506 35.461 1.00 34.36 ? 161 THR A CA 1 ATOM 1107 C C . THR A 1 160 ? 28.278 52.308 36.275 1.00 38.90 ? 161 THR A C 1 ATOM 1108 O O . THR A 1 160 ? 29.034 52.426 37.229 1.00 41.17 ? 161 THR A O 1 ATOM 1109 C CB . THR A 1 160 ? 28.974 54.050 34.565 1.00 34.04 ? 161 THR A CB 1 ATOM 1110 O OG1 . THR A 1 160 ? 28.448 55.180 33.855 1.00 34.59 ? 161 THR A OG1 1 ATOM 1111 C CG2 . THR A 1 160 ? 29.437 53.041 33.564 1.00 30.92 ? 161 THR A CG2 1 ATOM 1112 N N . LYS A 1 161 ? 27.699 51.167 35.967 1.00 34.46 ? 162 LYS A N 1 ATOM 1113 C CA . LYS A 1 161 ? 27.950 49.930 36.708 1.00 32.49 ? 162 LYS A CA 1 ATOM 1114 C C . LYS A 1 161 ? 28.666 48.918 35.825 1.00 38.82 ? 162 LYS A C 1 ATOM 1115 O O . LYS A 1 161 ? 28.231 48.651 34.696 1.00 38.40 ? 162 LYS A O 1 ATOM 1116 C CB . LYS A 1 161 ? 26.654 49.340 37.284 1.00 31.65 ? 162 LYS A CB 1 ATOM 1117 C CG . LYS A 1 161 ? 26.024 50.224 38.336 1.00 45.83 ? 162 LYS A CG 1 ATOM 1118 C CD . LYS A 1 161 ? 24.801 49.580 38.956 1.00 60.41 ? 162 LYS A CD 1 ATOM 1119 C CE . LYS A 1 161 ? 24.085 50.527 39.895 1.00 72.66 ? 162 LYS A CE 1 ATOM 1120 N NZ . LYS A 1 161 ? 22.710 50.036 40.217 1.00 85.13 ? 162 LYS A NZ 1 ATOM 1121 N N . SER A 1 162 ? 29.792 48.389 36.323 1.00 37.08 ? 163 SER A N 1 ATOM 1122 C CA . SER A 1 162 ? 30.545 47.395 35.573 1.00 37.32 ? 163 SER A CA 1 ATOM 1123 C C . SER A 1 162 ? 30.510 46.061 36.309 1.00 39.82 ? 163 SER A C 1 ATOM 1124 O O . SER A 1 162 ? 30.533 46.021 37.533 1.00 38.20 ? 163 SER A O 1 ATOM 1125 C CB . SER A 1 162 ? 31.968 47.875 35.282 1.00 41.81 ? 163 SER A CB 1 ATOM 1126 O OG . SER A 1 162 ? 32.796 47.685 36.419 1.00 59.68 ? 163 SER A OG 1 ATOM 1127 N N . GLU A 1 163 ? 30.358 44.983 35.564 1.00 38.97 ? 164 GLU A N 1 ATOM 1128 C CA . GLU A 1 163 ? 30.283 43.640 36.108 1.00 39.72 ? 164 GLU A CA 1 ATOM 1129 C C . GLU A 1 163 ? 31.325 42.773 35.423 1.00 41.57 ? 164 GLU A C 1 ATOM 1130 O O . GLU A 1 163 ? 31.266 42.580 34.218 1.00 39.27 ? 164 GLU A O 1 ATOM 1131 C CB . GLU A 1 163 ? 28.864 43.075 35.942 1.00 41.79 ? 164 GLU A CB 1 ATOM 1132 C CG . GLU A 1 163 ? 28.651 41.711 36.582 1.00 59.99 ? 164 GLU A CG 1 ATOM 1133 C CD . GLU A 1 163 ? 27.420 40.930 36.156 1.00 90.28 ? 164 GLU A CD 1 ATOM 1134 O OE1 . GLU A 1 163 ? 26.540 41.504 35.472 1.00 76.94 ? 164 GLU A OE1 1 ATOM 1135 O OE2 . GLU A 1 163 ? 27.335 39.735 36.526 1.00 96.76 ? 164 GLU A OE2 1 ATOM 1136 N N . SER A 1 164 ? 32.323 42.315 36.184 1.00 39.32 ? 165 SER A N 1 ATOM 1137 C CA . SER A 1 164 ? 33.368 41.444 35.658 1.00 40.22 ? 165 SER A CA 1 ATOM 1138 C C . SER A 1 164 ? 32.831 40.027 35.617 1.00 44.01 ? 165 SER A C 1 ATOM 1139 O O . SER A 1 164 ? 32.192 39.607 36.569 1.00 45.65 ? 165 SER A O 1 ATOM 1140 C CB . SER A 1 164 ? 34.627 41.521 36.516 1.00 45.96 ? 165 SER A CB 1 ATOM 1141 O OG . SER A 1 164 ? 34.316 41.251 37.872 1.00 69.49 ? 165 SER A OG 1 ATOM 1142 N N . HIS A 1 165 ? 33.047 39.317 34.513 1.00 39.27 ? 166 HIS A N 1 ATOM 1143 C CA . HIS A 1 165 ? 32.611 37.935 34.322 1.00 38.62 ? 166 HIS A CA 1 ATOM 1144 C C . HIS A 1 165 ? 33.815 37.024 34.425 1.00 48.26 ? 166 HIS A C 1 ATOM 1145 O O . HIS A 1 165 ? 34.940 37.439 34.099 1.00 49.93 ? 166 HIS A O 1 ATOM 1146 C CB . HIS A 1 165 ? 31.931 37.757 32.956 1.00 38.40 ? 166 HIS A CB 1 ATOM 1147 C CG . HIS A 1 165 ? 30.813 38.727 32.706 1.00 41.96 ? 166 HIS A CG 1 ATOM 1148 N ND1 . HIS A 1 165 ? 29.677 38.767 33.507 1.00 43.52 ? 166 HIS A ND1 1 ATOM 1149 C CD2 . HIS A 1 165 ? 30.699 39.673 31.752 1.00 43.95 ? 166 HIS A CD2 1 ATOM 1150 C CE1 . HIS A 1 165 ? 28.927 39.735 33.018 1.00 42.97 ? 166 HIS A CE1 1 ATOM 1151 N NE2 . HIS A 1 165 ? 29.496 40.302 31.959 1.00 43.63 ? 166 HIS A NE2 1 ATOM 1152 N N . SER A 1 166 ? 33.582 35.764 34.840 1.00 46.45 ? 167 SER A N 1 ATOM 1153 C CA . SER A 1 166 ? 34.629 34.747 35.003 1.00 45.85 ? 167 SER A CA 1 ATOM 1154 C C . SER A 1 166 ? 35.440 34.428 33.732 1.00 49.04 ? 167 SER A C 1 ATOM 1155 O O . SER A 1 166 ? 36.625 34.099 33.839 1.00 49.40 ? 167 SER A O 1 ATOM 1156 C CB . SER A 1 166 ? 34.099 33.501 35.708 1.00 49.23 ? 167 SER A CB 1 ATOM 1157 O OG . SER A 1 166 ? 33.179 32.760 34.924 1.00 61.37 ? 167 SER A OG 1 ATOM 1158 N N . ASN A 1 167 ? 34.841 34.614 32.536 1.00 44.29 ? 168 ASN A N 1 ATOM 1159 C CA . ASN A 1 167 ? 35.520 34.425 31.236 1.00 42.20 ? 168 ASN A CA 1 ATOM 1160 C C . ASN A 1 167 ? 36.495 35.564 30.865 1.00 43.63 ? 168 ASN A C 1 ATOM 1161 O O . ASN A 1 167 ? 37.196 35.453 29.860 1.00 45.03 ? 168 ASN A O 1 ATOM 1162 C CB . ASN A 1 167 ? 34.520 34.174 30.099 1.00 40.12 ? 168 ASN A CB 1 ATOM 1163 C CG . ASN A 1 167 ? 33.487 35.261 29.840 1.00 60.31 ? 168 ASN A CG 1 ATOM 1164 O OD1 . ASN A 1 167 ? 33.617 36.418 30.290 1.00 46.56 ? 168 ASN A OD1 1 ATOM 1165 N ND2 . ASN A 1 167 ? 32.447 34.874 29.083 1.00 53.12 ? 168 ASN A ND2 1 ATOM 1166 N N . GLY A 1 168 ? 36.531 36.632 31.658 1.00 37.52 ? 169 GLY A N 1 ATOM 1167 C CA . GLY A 1 168 ? 37.431 37.756 31.400 1.00 37.78 ? 169 GLY A CA 1 ATOM 1168 C C . GLY A 1 168 ? 36.820 38.952 30.691 1.00 41.69 ? 169 GLY A C 1 ATOM 1169 O O . GLY A 1 168 ? 37.514 39.933 30.411 1.00 41.93 ? 169 GLY A O 1 ATOM 1170 N N . THR A 1 169 ? 35.519 38.865 30.372 1.00 37.54 ? 170 THR A N 1 ATOM 1171 C CA . THR A 1 169 ? 34.775 39.947 29.756 1.00 36.57 ? 170 THR A CA 1 ATOM 1172 C C . THR A 1 169 ? 34.165 40.838 30.852 1.00 40.39 ? 170 THR A C 1 ATOM 1173 O O . THR A 1 169 ? 34.173 40.463 32.022 1.00 40.44 ? 170 THR A O 1 ATOM 1174 C CB . THR A 1 169 ? 33.762 39.441 28.727 1.00 33.66 ? 170 THR A CB 1 ATOM 1175 O OG1 . THR A 1 169 ? 32.666 38.830 29.375 1.00 31.14 ? 170 THR A OG1 1 ATOM 1176 C CG2 . THR A 1 169 ? 34.372 38.525 27.674 1.00 30.90 ? 170 THR A CG2 1 ATOM 1177 N N . VAL A 1 170 ? 33.709 42.043 30.483 1.00 36.77 ? 171 VAL A N 1 ATOM 1178 C CA . VAL A 1 170 ? 33.110 43.013 31.413 1.00 35.96 ? 171 VAL A CA 1 ATOM 1179 C C . VAL A 1 170 ? 31.878 43.598 30.744 1.00 38.35 ? 171 VAL A C 1 ATOM 1180 O O . VAL A 1 170 ? 31.933 44.017 29.591 1.00 37.77 ? 171 VAL A O 1 ATOM 1181 C CB . VAL A 1 170 ? 34.103 44.150 31.831 1.00 40.16 ? 171 VAL A CB 1 ATOM 1182 C CG1 . VAL A 1 170 ? 33.473 45.106 32.834 1.00 40.05 ? 171 VAL A CG1 1 ATOM 1183 C CG2 . VAL A 1 170 ? 35.421 43.602 32.382 1.00 39.46 ? 171 VAL A CG2 1 ATOM 1184 N N . THR A 1 171 ? 30.764 43.611 31.467 1.00 35.08 ? 172 THR A N 1 ATOM 1185 C CA . THR A 1 171 ? 29.529 44.251 31.052 1.00 33.23 ? 172 THR A CA 1 ATOM 1186 C C . THR A 1 171 ? 29.499 45.608 31.729 1.00 35.93 ? 172 THR A C 1 ATOM 1187 O O . THR A 1 171 ? 29.638 45.684 32.940 1.00 34.02 ? 172 THR A O 1 ATOM 1188 C CB . THR A 1 171 ? 28.304 43.405 31.393 1.00 36.28 ? 172 THR A CB 1 ATOM 1189 O OG1 . THR A 1 171 ? 28.274 42.270 30.523 1.00 39.87 ? 172 THR A OG1 1 ATOM 1190 C CG2 . THR A 1 171 ? 26.994 44.190 31.233 1.00 32.98 ? 172 THR A CG2 1 ATOM 1191 N N . VAL A 1 172 ? 29.353 46.688 30.941 1.00 33.46 ? 173 VAL A N 1 ATOM 1192 C CA . VAL A 1 172 ? 29.252 48.058 31.457 1.00 32.31 ? 173 VAL A CA 1 ATOM 1193 C C . VAL A 1 172 ? 27.833 48.575 31.104 1.00 35.22 ? 173 VAL A C 1 ATOM 1194 O O . VAL A 1 172 ? 27.417 48.455 29.960 1.00 33.83 ? 173 VAL A O 1 ATOM 1195 C CB . VAL A 1 172 ? 30.387 48.988 30.928 1.00 35.60 ? 173 VAL A CB 1 ATOM 1196 C CG1 . VAL A 1 172 ? 30.389 50.312 31.669 1.00 35.44 ? 173 VAL A CG1 1 ATOM 1197 C CG2 . VAL A 1 172 ? 31.753 48.342 31.077 1.00 35.34 ? 173 VAL A CG2 1 ATOM 1198 N N . ARG A 1 173 ? 27.089 49.087 32.104 1.00 33.97 ? 174 ARG A N 1 ATOM 1199 C CA . ARG A 1 173 ? 25.730 49.627 31.970 1.00 33.07 ? 174 ARG A CA 1 ATOM 1200 C C . ARG A 1 173 ? 25.695 51.038 32.540 1.00 35.34 ? 174 ARG A C 1 ATOM 1201 O O . ARG A 1 173 ? 25.965 51.230 33.726 1.00 35.28 ? 174 ARG A O 1 ATOM 1202 C CB . ARG A 1 173 ? 24.695 48.740 32.697 1.00 33.33 ? 174 ARG A CB 1 ATOM 1203 C CG . ARG A 1 173 ? 24.659 47.303 32.191 1.00 45.15 ? 174 ARG A CG 1 ATOM 1204 C CD . ARG A 1 173 ? 23.748 46.405 33.001 1.00 54.39 ? 174 ARG A CD 1 ATOM 1205 N NE . ARG A 1 173 ? 22.788 45.726 32.119 1.00 72.49 ? 174 ARG A NE 1 ATOM 1206 C CZ . ARG A 1 173 ? 22.749 44.413 31.881 1.00 87.69 ? 174 ARG A CZ 1 ATOM 1207 N NH1 . ARG A 1 173 ? 23.600 43.591 32.489 1.00 58.55 ? 174 ARG A NH1 1 ATOM 1208 N NH2 . ARG A 1 173 ? 21.839 43.910 31.051 1.00 84.38 ? 174 ARG A NH2 1 ATOM 1209 N N . SER A 1 174 ? 25.356 52.027 31.702 1.00 30.53 ? 175 SER A N 1 ATOM 1210 C CA . SER A 1 174 ? 25.278 53.427 32.133 1.00 29.93 ? 175 SER A CA 1 ATOM 1211 C C . SER A 1 174 ? 23.848 54.003 32.011 1.00 36.99 ? 175 SER A C 1 ATOM 1212 O O . SER A 1 174 ? 23.209 53.845 30.967 1.00 38.31 ? 175 SER A O 1 ATOM 1213 C CB . SER A 1 174 ? 26.255 54.278 31.332 1.00 29.51 ? 175 SER A CB 1 ATOM 1214 O OG . SER A 1 174 ? 26.358 55.579 31.882 1.00 32.69 ? 175 SER A OG 1 ATOM 1215 N N . THR A 1 175 ? 23.377 54.693 33.063 1.00 34.41 ? 176 THR A N 1 ATOM 1216 C CA . THR A 1 175 ? 22.071 55.368 33.122 1.00 35.48 ? 176 THR A CA 1 ATOM 1217 C C . THR A 1 175 ? 22.314 56.848 33.477 1.00 42.74 ? 176 THR A C 1 ATOM 1218 O O . THR A 1 175 ? 22.912 57.114 34.527 1.00 40.61 ? 176 THR A O 1 ATOM 1219 C CB . THR A 1 175 ? 21.139 54.693 34.156 1.00 40.23 ? 176 THR A CB 1 ATOM 1220 O OG1 . THR A 1 175 ? 21.000 53.301 33.853 1.00 45.86 ? 176 THR A OG1 1 ATOM 1221 C CG2 . THR A 1 175 ? 19.785 55.338 34.214 1.00 33.75 ? 176 THR A CG2 1 ATOM 1222 N N . CYS A 1 176 ? 21.897 57.798 32.595 1.00 42.77 ? 177 CYS A N 1 ATOM 1223 C CA . CYS A 1 176 ? 22.001 59.237 32.858 1.00 46.41 ? 177 CYS A CA 1 ATOM 1224 C C . CYS A 1 176 ? 20.689 59.941 32.914 1.00 51.65 ? 177 CYS A C 1 ATOM 1225 O O . CYS A 1 176 ? 19.710 59.515 32.323 1.00 49.50 ? 177 CYS A O 1 ATOM 1226 C CB . CYS A 1 176 ? 22.919 59.968 31.891 1.00 49.50 ? 177 CYS A CB 1 ATOM 1227 S SG . CYS A 1 176 ? 24.505 59.192 31.661 1.00 55.85 ? 177 CYS A SG 1 ATOM 1228 N N . HIS A 1 177 ? 20.770 61.148 33.433 1.00 51.75 ? 178 HIS A N 1 ATOM 1229 C CA . HIS A 1 177 ? 19.698 62.081 33.561 1.00 54.19 ? 178 HIS A CA 1 ATOM 1230 C C . HIS A 1 177 ? 20.296 63.425 33.264 1.00 56.05 ? 178 HIS A C 1 ATOM 1231 O O . HIS A 1 177 ? 21.419 63.703 33.663 1.00 57.05 ? 178 HIS A O 1 ATOM 1232 C CB . HIS A 1 177 ? 19.160 62.033 34.993 1.00 58.02 ? 178 HIS A CB 1 ATOM 1233 C CG . HIS A 1 177 ? 18.064 63.005 35.204 1.00 64.51 ? 178 HIS A CG 1 ATOM 1234 N ND1 . HIS A 1 177 ? 18.263 64.161 35.942 1.00 68.11 ? 178 HIS A ND1 1 ATOM 1235 C CD2 . HIS A 1 177 ? 16.814 63.022 34.674 1.00 68.74 ? 178 HIS A CD2 1 ATOM 1236 C CE1 . HIS A 1 177 ? 17.119 64.831 35.866 1.00 68.71 ? 178 HIS A CE1 1 ATOM 1237 N NE2 . HIS A 1 177 ? 16.221 64.190 35.096 1.00 69.14 ? 178 HIS A NE2 1 ATOM 1238 N N . TRP A 1 178 ? 19.572 64.257 32.550 1.00 51.40 ? 179 TRP A N 1 ATOM 1239 C CA . TRP A 1 178 ? 20.035 65.601 32.208 1.00 49.87 ? 179 TRP A CA 1 ATOM 1240 C C . TRP A 1 178 ? 19.145 66.639 32.859 1.00 64.00 ? 179 TRP A C 1 ATOM 1241 O O . TRP A 1 178 ? 17.925 66.545 32.743 1.00 64.14 ? 179 TRP A O 1 ATOM 1242 C CB . TRP A 1 178 ? 20.084 65.770 30.686 1.00 45.21 ? 179 TRP A CB 1 ATOM 1243 C CG . TRP A 1 178 ? 21.191 64.979 30.068 1.00 43.15 ? 179 TRP A CG 1 ATOM 1244 C CD1 . TRP A 1 178 ? 22.445 65.428 29.777 1.00 44.91 ? 179 TRP A CD1 1 ATOM 1245 C CD2 . TRP A 1 178 ? 21.171 63.586 29.719 1.00 41.44 ? 179 TRP A CD2 1 ATOM 1246 N NE1 . TRP A 1 178 ? 23.194 64.419 29.233 1.00 42.36 ? 179 TRP A NE1 1 ATOM 1247 C CE2 . TRP A 1 178 ? 22.451 63.272 29.204 1.00 42.94 ? 179 TRP A CE2 1 ATOM 1248 C CE3 . TRP A 1 178 ? 20.203 62.565 29.811 1.00 41.57 ? 179 TRP A CE3 1 ATOM 1249 C CZ2 . TRP A 1 178 ? 22.790 61.997 28.771 1.00 41.07 ? 179 TRP A CZ2 1 ATOM 1250 C CZ3 . TRP A 1 178 ? 20.550 61.286 29.393 1.00 42.40 ? 179 TRP A CZ3 1 ATOM 1251 C CH2 . TRP A 1 178 ? 21.832 61.015 28.879 1.00 42.66 ? 179 TRP A CH2 1 ATOM 1252 N N . GLU A 1 179 ? 19.739 67.598 33.584 1.00 69.04 ? 180 GLU A N 1 ATOM 1253 C CA . GLU A 1 179 ? 18.978 68.673 34.235 1.00 72.53 ? 180 GLU A CA 1 ATOM 1254 C C . GLU A 1 179 ? 18.321 69.558 33.154 1.00 81.50 ? 180 GLU A C 1 ATOM 1255 O O . GLU A 1 179 ? 17.089 69.520 33.003 1.00 80.79 ? 180 GLU A O 1 ATOM 1256 C CB . GLU A 1 179 ? 19.883 69.521 35.151 1.00 74.43 ? 180 GLU A CB 1 ATOM 1257 C CG . GLU A 1 179 ? 19.629 69.288 36.627 1.00 90.44 ? 180 GLU A CG 1 ATOM 1258 C CD . GLU A 1 179 ? 20.516 68.228 37.247 1.00 116.17 ? 180 GLU A CD 1 ATOM 1259 O OE1 . GLU A 1 179 ? 21.665 68.565 37.614 1.00 104.78 ? 180 GLU A OE1 1 ATOM 1260 O OE2 . GLU A 1 179 ? 20.058 67.069 37.382 1.00 114.26 ? 180 GLU A OE2 1 ATOM 1261 N N . GLN A 1 180 ? 19.172 70.282 32.359 1.00 81.46 ? 181 GLN A N 1 ATOM 1262 C CA . GLN A 1 180 ? 18.815 71.198 31.259 1.00 82.73 ? 181 GLN A CA 1 ATOM 1263 C C . GLN A 1 180 ? 17.626 70.679 30.441 1.00 89.95 ? 181 GLN A C 1 ATOM 1264 O O . GLN A 1 180 ? 17.722 69.598 29.850 1.00 90.60 ? 181 GLN A O 1 ATOM 1265 C CB . GLN A 1 180 ? 20.006 71.434 30.308 1.00 84.04 ? 181 GLN A CB 1 ATOM 1266 C CG . GLN A 1 180 ? 21.338 71.765 30.969 1.00 110.55 ? 181 GLN A CG 1 ATOM 1267 C CD . GLN A 1 180 ? 22.434 71.919 29.935 1.00 141.83 ? 181 GLN A CD 1 ATOM 1268 O OE1 . GLN A 1 180 ? 22.832 70.961 29.256 1.00 140.27 ? 181 GLN A OE1 1 ATOM 1269 N NE2 . GLN A 1 180 ? 22.950 73.135 29.794 1.00 135.09 ? 181 GLN A NE2 1 ATOM 1270 N N . ASN A 1 181 ? 16.498 71.428 30.425 1.00 86.58 ? 182 ASN A N 1 ATOM 1271 C CA . ASN A 1 181 ? 15.332 71.006 29.647 1.00 85.66 ? 182 ASN A CA 1 ATOM 1272 C C . ASN A 1 181 ? 15.478 71.319 28.146 1.00 87.75 ? 182 ASN A C 1 ATOM 1273 O O . ASN A 1 181 ? 14.654 70.871 27.338 1.00 88.29 ? 182 ASN A O 1 ATOM 1274 C CB . ASN A 1 181 ? 14.019 71.473 30.271 1.00 86.19 ? 182 ASN A CB 1 ATOM 1275 C CG . ASN A 1 181 ? 13.683 70.744 31.555 1.00 94.41 ? 182 ASN A CG 1 ATOM 1276 O OD1 . ASN A 1 181 ? 14.414 70.816 32.553 1.00 88.16 ? 182 ASN A OD1 1 ATOM 1277 N ND2 . ASN A 1 181 ? 12.554 70.042 31.566 1.00 76.12 ? 182 ASN A ND2 1 ATOM 1278 N N . ASN A 1 182 ? 16.594 72.005 27.772 1.00 81.13 ? 183 ASN A N 1 ATOM 1279 C CA . ASN A 1 182 ? 16.983 72.299 26.390 1.00 79.69 ? 183 ASN A CA 1 ATOM 1280 C C . ASN A 1 182 ? 17.602 71.036 25.710 1.00 78.62 ? 183 ASN A C 1 ATOM 1281 O O . ASN A 1 182 ? 17.852 71.013 24.494 1.00 77.75 ? 183 ASN A O 1 ATOM 1282 C CB . ASN A 1 182 ? 17.959 73.478 26.359 1.00 84.97 ? 183 ASN A CB 1 ATOM 1283 C CG . ASN A 1 182 ? 17.602 74.553 25.346 1.00 116.44 ? 183 ASN A CG 1 ATOM 1284 O OD1 . ASN A 1 182 ? 16.427 74.880 25.101 1.00 112.67 ? 183 ASN A OD1 1 ATOM 1285 N ND2 . ASN A 1 182 ? 18.619 75.160 24.756 1.00 107.70 ? 183 ASN A ND2 1 ATOM 1286 N N . VAL A 1 183 ? 17.806 69.963 26.508 1.00 70.78 ? 184 VAL A N 1 ATOM 1287 C CA . VAL A 1 183 ? 18.349 68.692 26.040 1.00 67.96 ? 184 VAL A CA 1 ATOM 1288 C C . VAL A 1 183 ? 17.191 67.764 25.677 1.00 64.69 ? 184 VAL A C 1 ATOM 1289 O O . VAL A 1 183 ? 16.370 67.409 26.533 1.00 62.75 ? 184 VAL A O 1 ATOM 1290 C CB . VAL A 1 183 ? 19.363 68.054 27.035 1.00 72.20 ? 184 VAL A CB 1 ATOM 1291 C CG1 . VAL A 1 183 ? 19.990 66.793 26.447 1.00 72.00 ? 184 VAL A CG1 1 ATOM 1292 C CG2 . VAL A 1 183 ? 20.453 69.052 27.432 1.00 72.09 ? 184 VAL A CG2 1 ATOM 1293 N N . SER A 1 184 ? 17.117 67.398 24.390 1.00 57.74 ? 185 SER A N 1 ATOM 1294 C CA . SER A 1 184 ? 16.074 66.507 23.894 1.00 56.47 ? 185 SER A CA 1 ATOM 1295 C C . SER A 1 184 ? 16.654 65.226 23.294 1.00 59.01 ? 185 SER A C 1 ATOM 1296 O O . SER A 1 184 ? 16.010 64.171 23.330 1.00 58.82 ? 185 SER A O 1 ATOM 1297 C CB . SER A 1 184 ? 15.173 67.230 22.893 1.00 59.45 ? 185 SER A CB 1 ATOM 1298 O OG . SER A 1 184 ? 15.899 67.942 21.905 1.00 65.21 ? 185 SER A OG 1 ATOM 1299 N N . VAL A 1 185 ? 17.866 65.335 22.720 1.00 53.79 ? 186 VAL A N 1 ATOM 1300 C CA . VAL A 1 185 ? 18.600 64.234 22.098 1.00 51.56 ? 186 VAL A CA 1 ATOM 1301 C C . VAL A 1 185 ? 19.981 64.136 22.751 1.00 51.01 ? 186 VAL A C 1 ATOM 1302 O O . VAL A 1 185 ? 20.677 65.145 22.934 1.00 51.24 ? 186 VAL A O 1 ATOM 1303 C CB . VAL A 1 185 ? 18.651 64.327 20.544 1.00 54.80 ? 186 VAL A CB 1 ATOM 1304 C CG1 . VAL A 1 185 ? 19.378 63.127 19.934 1.00 54.26 ? 186 VAL A CG1 1 ATOM 1305 C CG2 . VAL A 1 185 ? 17.236 64.417 19.961 1.00 54.79 ? 186 VAL A CG2 1 ATOM 1306 N N . VAL A 1 186 ? 20.332 62.915 23.165 1.00 42.29 ? 187 VAL A N 1 ATOM 1307 C CA . VAL A 1 186 ? 21.615 62.615 23.811 1.00 39.09 ? 187 VAL A CA 1 ATOM 1308 C C . VAL A 1 186 ? 22.373 61.594 22.989 1.00 41.27 ? 187 VAL A C 1 ATOM 1309 O O . VAL A 1 186 ? 21.772 60.817 22.239 1.00 40.54 ? 187 VAL A O 1 ATOM 1310 C CB . VAL A 1 186 ? 21.486 62.200 25.296 1.00 39.56 ? 187 VAL A CB 1 ATOM 1311 C CG1 . VAL A 1 186 ? 20.862 63.320 26.117 1.00 38.91 ? 187 VAL A CG1 1 ATOM 1312 C CG2 . VAL A 1 186 ? 20.708 60.894 25.456 1.00 38.54 ? 187 VAL A CG2 1 ATOM 1313 N N . SER A 1 187 ? 23.692 61.613 23.116 1.00 36.95 ? 188 SER A N 1 ATOM 1314 C CA . SER A 1 187 ? 24.521 60.703 22.360 1.00 37.13 ? 188 SER A CA 1 ATOM 1315 C C . SER A 1 187 ? 25.411 59.839 23.273 1.00 40.04 ? 188 SER A C 1 ATOM 1316 O O . SER A 1 187 ? 26.006 60.357 24.226 1.00 39.33 ? 188 SER A O 1 ATOM 1317 C CB . SER A 1 187 ? 25.346 61.492 21.357 1.00 42.49 ? 188 SER A CB 1 ATOM 1318 O OG . SER A 1 187 ? 25.951 60.595 20.444 1.00 61.44 ? 188 SER A OG 1 ATOM 1319 N N . CYS A 1 188 ? 25.452 58.522 23.013 1.00 35.21 ? 189 CYS A N 1 ATOM 1320 C CA . CYS A 1 188 ? 26.285 57.607 23.778 1.00 35.15 ? 189 CYS A CA 1 ATOM 1321 C C . CYS A 1 188 ? 27.372 57.069 22.903 1.00 37.72 ? 189 CYS A C 1 ATOM 1322 O O . CYS A 1 188 ? 27.085 56.497 21.844 1.00 34.24 ? 189 CYS A O 1 ATOM 1323 C CB . CYS A 1 188 ? 25.495 56.463 24.418 1.00 36.25 ? 189 CYS A CB 1 ATOM 1324 S SG . CYS A 1 188 ? 26.551 55.260 25.282 1.00 40.09 ? 189 CYS A SG 1 ATOM 1325 N N . LEU A 1 189 ? 28.626 57.191 23.380 1.00 34.90 ? 190 LEU A N 1 ATOM 1326 C CA . LEU A 1 189 ? 29.783 56.608 22.704 1.00 33.83 ? 190 LEU A CA 1 ATOM 1327 C C . LEU A 1 189 ? 30.301 55.427 23.532 1.00 39.09 ? 190 LEU A C 1 ATOM 1328 O O . LEU A 1 189 ? 30.609 55.574 24.725 1.00 38.29 ? 190 LEU A O 1 ATOM 1329 C CB . LEU A 1 189 ? 30.887 57.645 22.483 1.00 33.25 ? 190 LEU A CB 1 ATOM 1330 C CG . LEU A 1 189 ? 32.260 57.148 21.974 1.00 35.35 ? 190 LEU A CG 1 ATOM 1331 C CD1 . LEU A 1 189 ? 32.210 56.668 20.541 1.00 32.86 ? 190 LEU A CD1 1 ATOM 1332 C CD2 . LEU A 1 189 ? 33.325 58.221 22.173 1.00 35.29 ? 190 LEU A CD2 1 ATOM 1333 N N . VAL A 1 190 ? 30.342 54.249 22.905 1.00 34.97 ? 191 VAL A N 1 ATOM 1334 C CA . VAL A 1 190 ? 30.896 53.048 23.505 1.00 33.39 ? 191 VAL A CA 1 ATOM 1335 C C . VAL A 1 190 ? 32.275 52.873 22.834 1.00 35.31 ? 191 VAL A C 1 ATOM 1336 O O . VAL A 1 190 ? 32.349 52.409 21.681 1.00 32.28 ? 191 VAL A O 1 ATOM 1337 C CB . VAL A 1 190 ? 29.994 51.796 23.327 1.00 36.58 ? 191 VAL A CB 1 ATOM 1338 C CG1 . VAL A 1 190 ? 30.687 50.541 23.836 1.00 36.27 ? 191 VAL A CG1 1 ATOM 1339 C CG2 . VAL A 1 190 ? 28.658 51.965 24.010 1.00 35.84 ? 191 VAL A CG2 1 ATOM 1340 N N . SER A 1 191 ? 33.360 53.286 23.535 1.00 32.36 ? 192 SER A N 1 ATOM 1341 C CA . SER A 1 191 ? 34.733 53.147 23.001 1.00 32.19 ? 192 SER A CA 1 ATOM 1342 C C . SER A 1 191 ? 35.300 51.756 23.294 1.00 33.85 ? 192 SER A C 1 ATOM 1343 O O . SER A 1 191 ? 35.217 51.248 24.418 1.00 32.49 ? 192 SER A O 1 ATOM 1344 C CB . SER A 1 191 ? 35.675 54.168 23.623 1.00 38.94 ? 192 SER A CB 1 ATOM 1345 O OG . SER A 1 191 ? 35.198 55.474 23.398 1.00 58.50 ? 192 SER A OG 1 ATOM 1346 N N . HIS A 1 192 ? 35.921 51.176 22.299 1.00 30.84 ? 193 HIS A N 1 ATOM 1347 C CA . HIS A 1 192 ? 36.551 49.886 22.435 1.00 31.49 ? 193 HIS A CA 1 ATOM 1348 C C . HIS A 1 192 ? 37.661 49.752 21.410 1.00 38.88 ? 193 HIS A C 1 ATOM 1349 O O . HIS A 1 192 ? 37.500 50.215 20.284 1.00 40.13 ? 193 HIS A O 1 ATOM 1350 C CB . HIS A 1 192 ? 35.526 48.755 22.294 1.00 31.39 ? 193 HIS A CB 1 ATOM 1351 C CG . HIS A 1 192 ? 35.990 47.480 22.903 1.00 34.95 ? 193 HIS A CG 1 ATOM 1352 N ND1 . HIS A 1 192 ? 36.463 46.456 22.121 1.00 37.29 ? 193 HIS A ND1 1 ATOM 1353 C CD2 . HIS A 1 192 ? 36.048 47.112 24.207 1.00 36.24 ? 193 HIS A CD2 1 ATOM 1354 C CE1 . HIS A 1 192 ? 36.786 45.488 22.968 1.00 36.77 ? 193 HIS A CE1 1 ATOM 1355 N NE2 . HIS A 1 192 ? 36.538 45.839 24.235 1.00 36.48 ? 193 HIS A NE2 1 ATOM 1356 N N . SER A 1 193 ? 38.766 49.082 21.773 1.00 37.42 ? 194 SER A N 1 ATOM 1357 C CA . SER A 1 193 ? 39.877 48.847 20.841 1.00 38.50 ? 194 SER A CA 1 ATOM 1358 C C . SER A 1 193 ? 39.469 48.094 19.567 1.00 43.47 ? 194 SER A C 1 ATOM 1359 O O . SER A 1 193 ? 40.148 48.231 18.552 1.00 45.83 ? 194 SER A O 1 ATOM 1360 C CB . SER A 1 193 ? 41.036 48.146 21.535 1.00 41.98 ? 194 SER A CB 1 ATOM 1361 O OG . SER A 1 193 ? 40.599 46.965 22.180 1.00 47.76 ? 194 SER A OG 1 ATOM 1362 N N . THR A 1 194 ? 38.345 47.345 19.589 1.00 37.83 ? 195 THR A N 1 ATOM 1363 C CA . THR A 1 194 ? 37.863 46.620 18.404 1.00 37.46 ? 195 THR A CA 1 ATOM 1364 C C . THR A 1 194 ? 36.996 47.497 17.475 1.00 42.89 ? 195 THR A C 1 ATOM 1365 O O . THR A 1 194 ? 36.539 47.032 16.422 1.00 42.65 ? 195 THR A O 1 ATOM 1366 C CB . THR A 1 194 ? 37.069 45.374 18.822 1.00 42.44 ? 195 THR A CB 1 ATOM 1367 O OG1 . THR A 1 194 ? 35.981 45.751 19.655 1.00 41.81 ? 195 THR A OG1 1 ATOM 1368 C CG2 . THR A 1 194 ? 37.923 44.360 19.524 1.00 43.06 ? 195 THR A CG2 1 ATOM 1369 N N . GLY A 1 195 ? 36.740 48.728 17.903 1.00 39.83 ? 196 GLY A N 1 ATOM 1370 C CA . GLY A 1 195 ? 35.895 49.659 17.179 1.00 40.36 ? 196 GLY A CA 1 ATOM 1371 C C . GLY A 1 195 ? 34.887 50.362 18.068 1.00 44.09 ? 196 GLY A C 1 ATOM 1372 O O . GLY A 1 195 ? 34.240 49.740 18.918 1.00 43.16 ? 196 GLY A O 1 ATOM 1373 N N . ASN A 1 196 ? 34.771 51.677 17.873 1.00 39.66 ? 197 ASN A N 1 ATOM 1374 C CA . ASN A 1 196 ? 33.841 52.533 18.587 1.00 38.78 ? 197 ASN A CA 1 ATOM 1375 C C . ASN A 1 196 ? 32.433 52.385 18.011 1.00 40.65 ? 197 ASN A C 1 ATOM 1376 O O . ASN A 1 196 ? 32.278 52.062 16.832 1.00 39.70 ? 197 ASN A O 1 ATOM 1377 C CB . ASN A 1 196 ? 34.311 53.972 18.521 1.00 38.29 ? 197 ASN A CB 1 ATOM 1378 C CG . ASN A 1 196 ? 35.547 54.226 19.323 1.00 48.65 ? 197 ASN A CG 1 ATOM 1379 O OD1 . ASN A 1 196 ? 36.043 53.327 20.000 1.00 41.96 ? 197 ASN A OD1 1 ATOM 1380 N ND2 . ASN A 1 196 ? 36.056 55.448 19.264 1.00 58.41 ? 197 ASN A ND2 1 ATOM 1381 N N . GLN A 1 197 ? 31.412 52.530 18.867 1.00 34.98 ? 198 GLN A N 1 ATOM 1382 C CA . GLN A 1 197 ? 30.003 52.408 18.482 1.00 34.31 ? 198 GLN A CA 1 ATOM 1383 C C . GLN A 1 197 ? 29.273 53.524 19.181 1.00 38.83 ? 198 GLN A C 1 ATOM 1384 O O . GLN A 1 197 ? 29.450 53.722 20.396 1.00 39.13 ? 198 GLN A O 1 ATOM 1385 C CB . GLN A 1 197 ? 29.407 51.056 18.918 1.00 35.62 ? 198 GLN A CB 1 ATOM 1386 C CG . GLN A 1 197 ? 29.943 49.873 18.120 1.00 48.58 ? 198 GLN A CG 1 ATOM 1387 C CD . GLN A 1 197 ? 29.599 48.553 18.758 1.00 54.82 ? 198 GLN A CD 1 ATOM 1388 O OE1 . GLN A 1 197 ? 30.252 48.107 19.689 1.00 43.09 ? 198 GLN A OE1 1 ATOM 1389 N NE2 . GLN A 1 197 ? 28.607 47.867 18.228 1.00 43.95 ? 198 GLN A NE2 1 ATOM 1390 N N . SER A 1 198 ? 28.513 54.306 18.418 1.00 34.46 ? 199 SER A N 1 ATOM 1391 C CA . SER A 1 198 ? 27.750 55.396 19.007 1.00 33.59 ? 199 SER A CA 1 ATOM 1392 C C . SER A 1 198 ? 26.376 55.507 18.371 1.00 36.96 ? 199 SER A C 1 ATOM 1393 O O . SER A 1 198 ? 26.174 55.104 17.209 1.00 36.18 ? 199 SER A O 1 ATOM 1394 C CB . SER A 1 198 ? 28.522 56.710 18.969 1.00 35.01 ? 199 SER A CB 1 ATOM 1395 O OG . SER A 1 198 ? 28.706 57.123 17.630 1.00 49.42 ? 199 SER A OG 1 ATOM 1396 N N . LEU A 1 199 ? 25.421 55.974 19.161 1.00 32.46 ? 200 LEU A N 1 ATOM 1397 C CA . LEU A 1 199 ? 24.056 56.173 18.702 1.00 32.71 ? 200 LEU A CA 1 ATOM 1398 C C . LEU A 1 199 ? 23.427 57.269 19.521 1.00 37.31 ? 200 LEU A C 1 ATOM 1399 O O . LEU A 1 199 ? 23.781 57.430 20.696 1.00 35.63 ? 200 LEU A O 1 ATOM 1400 C CB . LEU A 1 199 ? 23.257 54.874 18.855 1.00 32.27 ? 200 LEU A CB 1 ATOM 1401 C CG . LEU A 1 199 ? 22.100 54.626 17.899 1.00 36.69 ? 200 LEU A CG 1 ATOM 1402 C CD1 . LEU A 1 199 ? 22.545 54.646 16.425 1.00 35.97 ? 200 LEU A CD1 1 ATOM 1403 C CD2 . LEU A 1 199 ? 21.473 53.256 18.157 1.00 37.97 ? 200 LEU A CD2 1 ATOM 1404 N N . SER A 1 200 ? 22.490 58.033 18.905 1.00 34.54 ? 201 SER A N 1 ATOM 1405 C CA . SER A 1 200 ? 21.743 59.067 19.619 1.00 32.99 ? 201 SER A CA 1 ATOM 1406 C C . SER A 1 200 ? 20.408 58.525 20.130 1.00 36.01 ? 201 SER A C 1 ATOM 1407 O O . SER A 1 200 ? 19.831 57.605 19.535 1.00 33.61 ? 201 SER A O 1 ATOM 1408 C CB . SER A 1 200 ? 21.575 60.318 18.778 1.00 36.11 ? 201 SER A CB 1 ATOM 1409 O OG . SER A 1 200 ? 22.820 60.962 18.579 1.00 44.58 ? 201 SER A OG 1 ATOM 1410 N N . ILE A 1 201 ? 19.974 59.035 21.293 1.00 34.99 ? 202 ILE A N 1 ATOM 1411 C CA . ILE A 1 201 ? 18.743 58.624 21.972 1.00 35.87 ? 202 ILE A CA 1 ATOM 1412 C C . ILE A 1 201 ? 17.869 59.868 22.188 1.00 44.21 ? 202 ILE A C 1 ATOM 1413 O O . ILE A 1 201 ? 18.315 60.875 22.764 1.00 42.32 ? 202 ILE A O 1 ATOM 1414 C CB . ILE A 1 201 ? 19.012 57.897 23.333 1.00 37.94 ? 202 ILE A CB 1 ATOM 1415 C CG1 . ILE A 1 201 ? 20.043 56.747 23.200 1.00 37.79 ? 202 ILE A CG1 1 ATOM 1416 C CG2 . ILE A 1 201 ? 17.710 57.399 23.953 1.00 36.50 ? 202 ILE A CG2 1 ATOM 1417 C CD1 . ILE A 1 201 ? 20.642 56.292 24.521 1.00 36.54 ? 202 ILE A CD1 1 ATOM 1418 N N . GLU A 1 202 ? 16.602 59.756 21.775 1.00 43.03 ? 203 GLU A N 1 ATOM 1419 C CA . GLU A 1 202 ? 15.626 60.801 21.957 1.00 43.60 ? 203 GLU A CA 1 ATOM 1420 C C . GLU A 1 202 ? 15.030 60.653 23.364 1.00 47.29 ? 203 GLU A C 1 ATOM 1421 O O . GLU A 1 202 ? 14.463 59.608 23.702 1.00 46.79 ? 203 GLU A O 1 ATOM 1422 C CB . GLU A 1 202 ? 14.563 60.640 20.881 1.00 45.50 ? 203 GLU A CB 1 ATOM 1423 C CG . GLU A 1 202 ? 13.608 61.803 20.726 1.00 63.83 ? 203 GLU A CG 1 ATOM 1424 C CD . GLU A 1 202 ? 12.513 61.467 19.725 1.00 91.95 ? 203 GLU A CD 1 ATOM 1425 O OE1 . GLU A 1 202 ? 12.820 61.379 18.511 1.00 91.25 ? 203 GLU A OE1 1 ATOM 1426 O OE2 . GLU A 1 202 ? 11.369 61.207 20.166 1.00 81.30 ? 203 GLU A OE2 1 ATOM 1427 N N . LEU A 1 203 ? 15.191 61.683 24.191 1.00 44.33 ? 204 LEU A N 1 ATOM 1428 C CA . LEU A 1 203 ? 14.641 61.659 25.550 1.00 45.58 ? 204 LEU A CA 1 ATOM 1429 C C . LEU A 1 203 ? 13.100 61.765 25.514 1.00 55.37 ? 204 LEU A C 1 ATOM 1430 O O . LEU A 1 203 ? 12.556 62.406 24.609 1.00 55.80 ? 204 LEU A O 1 ATOM 1431 C CB . LEU A 1 203 ? 15.237 62.804 26.398 1.00 44.57 ? 204 LEU A CB 1 ATOM 1432 C CG . LEU A 1 203 ? 16.762 62.772 26.625 1.00 48.05 ? 204 LEU A CG 1 ATOM 1433 C CD1 . LEU A 1 203 ? 17.220 63.899 27.566 1.00 46.86 ? 204 LEU A CD1 1 ATOM 1434 C CD2 . LEU A 1 203 ? 17.222 61.412 27.158 1.00 47.37 ? 204 LEU A CD2 1 ATOM 1435 N N . SER A 1 204 ? 12.412 61.138 26.501 1.00 53.78 ? 205 SER A N 1 ATOM 1436 C CA . SER A 1 204 ? 10.954 61.145 26.681 1.00 74.29 ? 205 SER A CA 1 ATOM 1437 C C . SER A 1 204 ? 10.417 62.571 26.918 1.00 119.03 ? 205 SER A C 1 ATOM 1438 O O . SER A 1 204 ? 11.099 63.410 27.513 1.00 83.54 ? 205 SER A O 1 ATOM 1439 C CB . SER A 1 204 ? 10.560 60.253 27.853 1.00 77.78 ? 205 SER A CB 1 ATOM 1440 O OG . SER A 1 204 ? 10.900 60.840 29.100 1.00 88.54 ? 205 SER A OG 1 ATOM 1441 N N . GLN B 1 17 ? 22.142 66.638 14.672 1.00 79.98 ? 18 GLN B N 1 ATOM 1442 C CA . GLN B 1 17 ? 23.257 67.448 15.190 1.00 79.82 ? 18 GLN B CA 1 ATOM 1443 C C . GLN B 1 17 ? 24.578 66.674 15.427 1.00 80.92 ? 18 GLN B C 1 ATOM 1444 O O . GLN B 1 17 ? 25.517 66.925 14.669 1.00 81.43 ? 18 GLN B O 1 ATOM 1445 C CB . GLN B 1 17 ? 22.842 68.366 16.369 1.00 81.64 ? 18 GLN B CB 1 ATOM 1446 C CG . GLN B 1 17 ? 23.907 69.395 16.810 1.00 105.40 ? 18 GLN B CG 1 ATOM 1447 C CD . GLN B 1 17 ? 24.480 70.247 15.692 1.00 132.18 ? 18 GLN B CD 1 ATOM 1448 O OE1 . GLN B 1 17 ? 23.756 70.820 14.860 1.00 128.39 ? 18 GLN B OE1 1 ATOM 1449 N NE2 . GLN B 1 17 ? 25.803 70.362 15.666 1.00 125.67 ? 18 GLN B NE2 1 ATOM 1450 N N . VAL B 1 18 ? 24.682 65.769 16.466 1.00 73.87 ? 19 VAL B N 1 ATOM 1451 C CA . VAL B 1 18 ? 25.904 64.932 16.645 1.00 70.96 ? 19 VAL B CA 1 ATOM 1452 C C . VAL B 1 18 ? 25.940 64.004 15.418 1.00 69.86 ? 19 VAL B C 1 ATOM 1453 O O . VAL B 1 18 ? 24.922 63.359 15.101 1.00 68.04 ? 19 VAL B O 1 ATOM 1454 C CB . VAL B 1 18 ? 26.041 64.155 17.996 1.00 73.16 ? 19 VAL B CB 1 ATOM 1455 C CG1 . VAL B 1 18 ? 27.173 63.128 17.947 1.00 71.84 ? 19 VAL B CG1 1 ATOM 1456 C CG2 . VAL B 1 18 ? 26.264 65.120 19.155 1.00 73.20 ? 19 VAL B CG2 1 ATOM 1457 N N . ASN B 1 19 ? 27.076 64.013 14.690 1.00 62.10 ? 20 ASN B N 1 ATOM 1458 C CA . ASN B 1 19 ? 27.191 63.257 13.457 1.00 59.93 ? 20 ASN B CA 1 ATOM 1459 C C . ASN B 1 19 ? 28.594 62.755 13.147 1.00 61.99 ? 20 ASN B C 1 ATOM 1460 O O . ASN B 1 19 ? 29.588 63.229 13.706 1.00 62.10 ? 20 ASN B O 1 ATOM 1461 C CB . ASN B 1 19 ? 26.652 64.112 12.290 1.00 57.40 ? 20 ASN B CB 1 ATOM 1462 C CG . ASN B 1 19 ? 27.587 65.186 11.797 1.00 91.56 ? 20 ASN B CG 1 ATOM 1463 O OD1 . ASN B 1 19 ? 28.545 64.908 11.063 1.00 84.28 ? 20 ASN B OD1 1 ATOM 1464 N ND2 . ASN B 1 19 ? 27.314 66.434 12.174 1.00 97.34 ? 20 ASN B ND2 1 ATOM 1465 N N . THR B 1 20 ? 28.660 61.839 12.185 1.00 56.65 ? 21 THR B N 1 ATOM 1466 C CA . THR B 1 20 ? 29.885 61.303 11.623 1.00 54.99 ? 21 THR B CA 1 ATOM 1467 C C . THR B 1 20 ? 30.107 62.035 10.280 1.00 57.95 ? 21 THR B C 1 ATOM 1468 O O . THR B 1 20 ? 29.250 61.962 9.393 1.00 56.86 ? 21 THR B O 1 ATOM 1469 C CB . THR B 1 20 ? 29.736 59.780 11.430 1.00 55.12 ? 21 THR B CB 1 ATOM 1470 O OG1 . THR B 1 20 ? 29.313 59.169 12.657 1.00 48.30 ? 21 THR B OG1 1 ATOM 1471 C CG2 . THR B 1 20 ? 31.000 59.121 10.869 1.00 47.87 ? 21 THR B CG2 1 ATOM 1472 N N . THR B 1 21 ? 31.235 62.771 10.145 1.00 53.80 ? 22 THR B N 1 ATOM 1473 C CA . THR B 1 21 ? 31.577 63.392 8.868 1.00 52.66 ? 22 THR B CA 1 ATOM 1474 C C . THR B 1 21 ? 32.286 62.322 8.059 1.00 53.99 ? 22 THR B C 1 ATOM 1475 O O . THR B 1 21 ? 33.113 61.590 8.584 1.00 54.59 ? 22 THR B O 1 ATOM 1476 C CB . THR B 1 21 ? 32.347 64.698 9.020 1.00 63.90 ? 22 THR B CB 1 ATOM 1477 O OG1 . THR B 1 21 ? 31.526 65.615 9.730 1.00 65.58 ? 22 THR B OG1 1 ATOM 1478 C CG2 . THR B 1 21 ? 32.674 65.334 7.673 1.00 65.14 ? 22 THR B CG2 1 ATOM 1479 N N . MET B 1 22 ? 31.906 62.179 6.813 1.00 48.32 ? 23 MET B N 1 ATOM 1480 C CA . MET B 1 22 ? 32.451 61.168 5.932 1.00 47.57 ? 23 MET B CA 1 ATOM 1481 C C . MET B 1 22 ? 32.800 61.847 4.587 1.00 49.65 ? 23 MET B C 1 ATOM 1482 O O . MET B 1 22 ? 31.970 62.579 4.054 1.00 48.76 ? 23 MET B O 1 ATOM 1483 C CB . MET B 1 22 ? 31.391 60.059 5.774 1.00 50.58 ? 23 MET B CB 1 ATOM 1484 C CG . MET B 1 22 ? 31.868 58.857 5.052 1.00 56.60 ? 23 MET B CG 1 ATOM 1485 S SD . MET B 1 22 ? 30.580 57.545 5.128 1.00 63.62 ? 23 MET B SD 1 ATOM 1486 C CE . MET B 1 22 ? 31.195 56.459 3.893 1.00 60.26 ? 23 MET B CE 1 ATOM 1487 N N . SER B 1 23 ? 34.053 61.673 4.087 1.00 44.08 ? 24 SER B N 1 ATOM 1488 C CA . SER B 1 23 ? 34.509 62.180 2.781 1.00 41.94 ? 24 SER B CA 1 ATOM 1489 C C . SER B 1 23 ? 34.679 61.021 1.857 1.00 46.08 ? 24 SER B C 1 ATOM 1490 O O . SER B 1 23 ? 35.323 60.056 2.229 1.00 48.04 ? 24 SER B O 1 ATOM 1491 C CB . SER B 1 23 ? 35.814 62.944 2.891 1.00 43.29 ? 24 SER B CB 1 ATOM 1492 O OG . SER B 1 23 ? 35.560 64.195 3.501 1.00 56.71 ? 24 SER B OG 1 ATOM 1493 N N . VAL B 1 24 ? 34.021 61.047 0.698 1.00 41.77 ? 25 VAL B N 1 ATOM 1494 C CA . VAL B 1 24 ? 34.100 59.960 -0.274 1.00 40.69 ? 25 VAL B CA 1 ATOM 1495 C C . VAL B 1 24 ? 34.395 60.546 -1.642 1.00 45.01 ? 25 VAL B C 1 ATOM 1496 O O . VAL B 1 24 ? 33.867 61.595 -2.008 1.00 43.67 ? 25 VAL B O 1 ATOM 1497 C CB . VAL B 1 24 ? 32.895 58.957 -0.271 1.00 43.92 ? 25 VAL B CB 1 ATOM 1498 C CG1 . VAL B 1 24 ? 33.152 57.780 -1.227 1.00 43.73 ? 25 VAL B CG1 1 ATOM 1499 C CG2 . VAL B 1 24 ? 32.622 58.412 1.131 1.00 43.22 ? 25 VAL B CG2 1 ATOM 1500 N N . GLN B 1 25 ? 35.269 59.872 -2.381 1.00 43.16 ? 26 GLN B N 1 ATOM 1501 C CA . GLN B 1 25 ? 35.687 60.265 -3.704 1.00 42.54 ? 26 GLN B CA 1 ATOM 1502 C C . GLN B 1 25 ? 34.689 59.799 -4.738 1.00 45.85 ? 26 GLN B C 1 ATOM 1503 O O . GLN B 1 25 ? 34.134 58.709 -4.621 1.00 45.84 ? 26 GLN B O 1 ATOM 1504 C CB . GLN B 1 25 ? 37.037 59.624 -3.994 1.00 44.12 ? 26 GLN B CB 1 ATOM 1505 C CG . GLN B 1 25 ? 37.870 60.387 -5.011 1.00 62.43 ? 26 GLN B CG 1 ATOM 1506 C CD . GLN B 1 25 ? 39.213 59.742 -5.196 1.00 73.48 ? 26 GLN B CD 1 ATOM 1507 O OE1 . GLN B 1 25 ? 40.031 59.655 -4.258 1.00 70.15 ? 26 GLN B OE1 1 ATOM 1508 N NE2 . GLN B 1 25 ? 39.457 59.269 -6.404 1.00 62.12 ? 26 GLN B NE2 1 ATOM 1509 N N . MET B 1 26 ? 34.524 60.603 -5.793 1.00 41.73 ? 27 MET B N 1 ATOM 1510 C CA . MET B 1 26 ? 33.696 60.309 -6.948 1.00 41.76 ? 27 MET B CA 1 ATOM 1511 C C . MET B 1 26 ? 33.956 58.875 -7.426 1.00 47.93 ? 27 MET B C 1 ATOM 1512 O O . MET B 1 26 ? 35.105 58.438 -7.427 1.00 48.90 ? 27 MET B O 1 ATOM 1513 C CB . MET B 1 26 ? 34.088 61.267 -8.087 1.00 43.95 ? 27 MET B CB 1 ATOM 1514 C CG . MET B 1 26 ? 33.516 62.648 -7.942 1.00 47.91 ? 27 MET B CG 1 ATOM 1515 S SD . MET B 1 26 ? 31.754 62.741 -8.381 1.00 52.01 ? 27 MET B SD 1 ATOM 1516 C CE . MET B 1 26 ? 31.835 62.611 -10.159 1.00 47.23 ? 27 MET B CE 1 ATOM 1517 N N . ASP B 1 27 ? 32.897 58.153 -7.830 1.00 45.84 ? 28 ASP B N 1 ATOM 1518 C CA . ASP B 1 27 ? 32.936 56.797 -8.393 1.00 45.96 ? 28 ASP B CA 1 ATOM 1519 C C . ASP B 1 27 ? 33.220 55.652 -7.437 1.00 49.10 ? 28 ASP B C 1 ATOM 1520 O O . ASP B 1 27 ? 33.086 54.499 -7.827 1.00 50.89 ? 28 ASP B O 1 ATOM 1521 C CB . ASP B 1 27 ? 33.821 56.713 -9.654 1.00 48.38 ? 28 ASP B CB 1 ATOM 1522 C CG . ASP B 1 27 ? 33.531 57.780 -10.688 1.00 64.90 ? 28 ASP B CG 1 ATOM 1523 O OD1 . ASP B 1 27 ? 32.341 57.937 -11.067 1.00 65.88 ? 28 ASP B OD1 1 ATOM 1524 O OD2 . ASP B 1 27 ? 34.494 58.453 -11.130 1.00 74.59 ? 28 ASP B OD2 1 ATOM 1525 N N . LYS B 1 28 ? 33.595 55.949 -6.203 1.00 44.47 ? 29 LYS B N 1 ATOM 1526 C CA . LYS B 1 28 ? 33.868 54.930 -5.191 1.00 44.98 ? 29 LYS B CA 1 ATOM 1527 C C . LYS B 1 28 ? 32.559 54.505 -4.517 1.00 50.90 ? 29 LYS B C 1 ATOM 1528 O O . LYS B 1 28 ? 31.551 55.200 -4.653 1.00 53.60 ? 29 LYS B O 1 ATOM 1529 C CB . LYS B 1 28 ? 34.882 55.449 -4.147 1.00 47.52 ? 29 LYS B CB 1 ATOM 1530 C CG . LYS B 1 28 ? 36.188 55.997 -4.733 1.00 71.83 ? 29 LYS B CG 1 ATOM 1531 C CD . LYS B 1 28 ? 37.061 54.922 -5.352 1.00 86.09 ? 29 LYS B CD 1 ATOM 1532 C CE . LYS B 1 28 ? 38.421 55.421 -5.756 1.00 98.05 ? 29 LYS B CE 1 ATOM 1533 N NZ . LYS B 1 28 ? 39.166 54.346 -6.448 1.00 110.21 ? 29 LYS B NZ 1 ATOM 1534 N N . LYS B 1 29 ? 32.566 53.360 -3.819 1.00 45.06 ? 30 LYS B N 1 ATOM 1535 C CA . LYS B 1 29 ? 31.409 52.833 -3.110 1.00 43.48 ? 30 LYS B CA 1 ATOM 1536 C C . LYS B 1 29 ? 31.394 53.386 -1.697 1.00 48.33 ? 30 LYS B C 1 ATOM 1537 O O . LYS B 1 29 ? 32.456 53.590 -1.106 1.00 49.28 ? 30 LYS B O 1 ATOM 1538 C CB . LYS B 1 29 ? 31.432 51.286 -3.112 1.00 43.93 ? 30 LYS B CB 1 ATOM 1539 C CG . LYS B 1 29 ? 30.258 50.622 -2.359 1.00 48.99 ? 30 LYS B CG 1 ATOM 1540 C CD . LYS B 1 29 ? 30.146 49.145 -2.606 1.00 53.43 ? 30 LYS B CD 1 ATOM 1541 C CE . LYS B 1 29 ? 30.665 48.335 -1.444 1.00 73.59 ? 30 LYS B CE 1 ATOM 1542 N NZ . LYS B 1 29 ? 30.127 46.939 -1.457 1.00 80.25 ? 30 LYS B NZ 1 ATOM 1543 N N . ALA B 1 30 ? 30.193 53.631 -1.140 1.00 44.42 ? 31 ALA B N 1 ATOM 1544 C CA . ALA B 1 30 ? 30.098 54.125 0.238 1.00 43.37 ? 31 ALA B CA 1 ATOM 1545 C C . ALA B 1 30 ? 29.156 53.259 1.021 1.00 43.69 ? 31 ALA B C 1 ATOM 1546 O O . ALA B 1 30 ? 28.150 52.824 0.491 1.00 42.48 ? 31 ALA B O 1 ATOM 1547 C CB . ALA B 1 30 ? 29.659 55.586 0.283 1.00 43.95 ? 31 ALA B CB 1 ATOM 1548 N N . LEU B 1 31 ? 29.503 52.972 2.273 1.00 39.87 ? 32 LEU B N 1 ATOM 1549 C CA . LEU B 1 31 ? 28.677 52.164 3.159 1.00 38.60 ? 32 LEU B CA 1 ATOM 1550 C C . LEU B 1 31 ? 28.463 52.930 4.431 1.00 42.63 ? 32 LEU B C 1 ATOM 1551 O O . LEU B 1 31 ? 29.421 53.388 5.029 1.00 41.43 ? 32 LEU B O 1 ATOM 1552 C CB . LEU B 1 31 ? 29.298 50.793 3.414 1.00 38.37 ? 32 LEU B CB 1 ATOM 1553 C CG . LEU B 1 31 ? 29.275 49.819 2.214 1.00 42.49 ? 32 LEU B CG 1 ATOM 1554 C CD1 . LEU B 1 31 ? 30.188 48.646 2.460 1.00 43.10 ? 32 LEU B CD1 1 ATOM 1555 C CD2 . LEU B 1 31 ? 27.883 49.298 1.932 1.00 40.33 ? 32 LEU B CD2 1 ATOM 1556 N N . LEU B 1 32 ? 27.197 53.166 4.793 1.00 41.18 ? 33 LEU B N 1 ATOM 1557 C CA . LEU B 1 32 ? 26.836 53.946 5.970 1.00 40.58 ? 33 LEU B CA 1 ATOM 1558 C C . LEU B 1 32 ? 26.158 52.992 6.924 1.00 47.00 ? 33 LEU B C 1 ATOM 1559 O O . LEU B 1 32 ? 25.107 52.450 6.622 1.00 46.29 ? 33 LEU B O 1 ATOM 1560 C CB . LEU B 1 32 ? 25.928 55.124 5.579 1.00 40.50 ? 33 LEU B CB 1 ATOM 1561 C CG . LEU B 1 32 ? 26.585 56.342 4.914 1.00 46.71 ? 33 LEU B CG 1 ATOM 1562 C CD1 . LEU B 1 32 ? 27.038 56.062 3.485 1.00 47.72 ? 33 LEU B CD1 1 ATOM 1563 C CD2 . LEU B 1 32 ? 25.612 57.460 4.799 1.00 47.43 ? 33 LEU B CD2 1 ATOM 1564 N N . CYS B 1 33 ? 26.820 52.702 8.022 1.00 48.14 ? 34 CYS B N 1 ATOM 1565 C CA . CYS B 1 33 ? 26.334 51.760 9.008 1.00 49.95 ? 34 CYS B CA 1 ATOM 1566 C C . CYS B 1 33 ? 25.389 52.438 9.957 1.00 48.28 ? 34 CYS B C 1 ATOM 1567 O O . CYS B 1 33 ? 25.737 53.442 10.582 1.00 47.75 ? 34 CYS B O 1 ATOM 1568 C CB . CYS B 1 33 ? 27.491 51.094 9.757 1.00 53.35 ? 34 CYS B CB 1 ATOM 1569 S SG . CYS B 1 33 ? 26.976 49.751 10.876 1.00 59.06 ? 34 CYS B SG 1 ATOM 1570 N N . CYS B 1 34 ? 24.213 51.868 10.119 1.00 42.25 ? 35 CYS B N 1 ATOM 1571 C CA . CYS B 1 34 ? 23.276 52.465 11.054 1.00 42.84 ? 35 CYS B CA 1 ATOM 1572 C C . CYS B 1 34 ? 23.654 52.104 12.534 1.00 45.19 ? 35 CYS B C 1 ATOM 1573 O O . CYS B 1 34 ? 23.800 52.983 13.380 1.00 45.50 ? 35 CYS B O 1 ATOM 1574 C CB . CYS B 1 34 ? 21.853 52.057 10.696 1.00 44.49 ? 35 CYS B CB 1 ATOM 1575 S SG . CYS B 1 34 ? 20.603 52.882 11.694 1.00 49.09 ? 35 CYS B SG 1 ATOM 1576 N N . PHE B 1 35 ? 23.871 50.804 12.796 1.00 39.11 ? 36 PHE B N 1 ATOM 1577 C CA . PHE B 1 35 ? 24.333 50.205 14.041 1.00 37.94 ? 36 PHE B CA 1 ATOM 1578 C C . PHE B 1 35 ? 24.676 48.768 13.706 1.00 43.75 ? 36 PHE B C 1 ATOM 1579 O O . PHE B 1 35 ? 24.199 48.251 12.695 1.00 41.44 ? 36 PHE B O 1 ATOM 1580 C CB . PHE B 1 35 ? 23.262 50.252 15.175 1.00 38.80 ? 36 PHE B CB 1 ATOM 1581 C CG . PHE B 1 35 ? 21.994 49.471 14.936 1.00 38.82 ? 36 PHE B CG 1 ATOM 1582 C CD1 . PHE B 1 35 ? 21.973 48.085 15.052 1.00 41.54 ? 36 PHE B CD1 1 ATOM 1583 C CD2 . PHE B 1 35 ? 20.820 50.116 14.594 1.00 40.45 ? 36 PHE B CD2 1 ATOM 1584 C CE1 . PHE B 1 35 ? 20.806 47.354 14.774 1.00 42.02 ? 36 PHE B CE1 1 ATOM 1585 C CE2 . PHE B 1 35 ? 19.646 49.386 14.349 1.00 43.34 ? 36 PHE B CE2 1 ATOM 1586 C CZ . PHE B 1 35 ? 19.648 48.009 14.445 1.00 41.17 ? 36 PHE B CZ 1 ATOM 1587 N N . SER B 1 36 ? 25.466 48.107 14.555 1.00 44.49 ? 37 SER B N 1 ATOM 1588 C CA . SER B 1 36 ? 25.767 46.694 14.353 1.00 45.64 ? 37 SER B CA 1 ATOM 1589 C C . SER B 1 36 ? 25.704 46.018 15.703 1.00 52.62 ? 37 SER B C 1 ATOM 1590 O O . SER B 1 36 ? 26.669 46.085 16.468 1.00 55.47 ? 37 SER B O 1 ATOM 1591 C CB . SER B 1 36 ? 27.120 46.500 13.684 1.00 48.94 ? 37 SER B CB 1 ATOM 1592 O OG . SER B 1 36 ? 27.229 45.134 13.324 1.00 59.01 ? 37 SER B OG 1 ATOM 1593 N N . SER B 1 37 ? 24.535 45.454 16.042 1.00 47.50 ? 38 SER B N 1 ATOM 1594 C CA . SER B 1 37 ? 24.306 44.813 17.337 1.00 45.60 ? 38 SER B CA 1 ATOM 1595 C C . SER B 1 37 ? 23.145 43.846 17.282 1.00 51.00 ? 38 SER B C 1 ATOM 1596 O O . SER B 1 37 ? 22.065 44.235 16.840 1.00 50.11 ? 38 SER B O 1 ATOM 1597 C CB . SER B 1 37 ? 24.031 45.852 18.419 1.00 43.71 ? 38 SER B CB 1 ATOM 1598 O OG . SER B 1 37 ? 23.813 45.236 19.679 1.00 44.62 ? 38 SER B OG 1 ATOM 1599 N N . PRO B 1 38 ? 23.295 42.615 17.816 1.00 49.66 ? 39 PRO B N 1 ATOM 1600 C CA . PRO B 1 38 ? 22.135 41.699 17.875 1.00 49.13 ? 39 PRO B CA 1 ATOM 1601 C C . PRO B 1 38 ? 21.134 42.084 18.988 1.00 51.13 ? 39 PRO B C 1 ATOM 1602 O O . PRO B 1 38 ? 20.030 41.538 19.048 1.00 51.37 ? 39 PRO B O 1 ATOM 1603 C CB . PRO B 1 38 ? 22.780 40.338 18.151 1.00 50.57 ? 39 PRO B CB 1 ATOM 1604 C CG . PRO B 1 38 ? 24.013 40.667 18.919 1.00 55.87 ? 39 PRO B CG 1 ATOM 1605 C CD . PRO B 1 38 ? 24.505 42.001 18.412 1.00 51.86 ? 39 PRO B CD 1 ATOM 1606 N N . LEU B 1 39 ? 21.504 43.048 19.840 1.00 45.31 ? 40 LEU B N 1 ATOM 1607 C CA . LEU B 1 39 ? 20.696 43.464 20.979 1.00 44.79 ? 40 LEU B CA 1 ATOM 1608 C C . LEU B 1 39 ? 19.704 44.580 20.730 1.00 49.65 ? 40 LEU B C 1 ATOM 1609 O O . LEU B 1 39 ? 18.825 44.792 21.565 1.00 48.29 ? 40 LEU B O 1 ATOM 1610 C CB . LEU B 1 39 ? 21.598 43.819 22.180 1.00 44.67 ? 40 LEU B CB 1 ATOM 1611 C CG . LEU B 1 39 ? 22.685 42.806 22.603 1.00 48.71 ? 40 LEU B CG 1 ATOM 1612 C CD1 . LEU B 1 39 ? 23.318 43.256 23.888 1.00 49.37 ? 40 LEU B CD1 1 ATOM 1613 C CD2 . LEU B 1 39 ? 22.112 41.413 22.825 1.00 46.86 ? 40 LEU B CD2 1 ATOM 1614 N N . ILE B 1 40 ? 19.865 45.343 19.641 1.00 48.51 ? 41 ILE B N 1 ATOM 1615 C CA . ILE B 1 40 ? 18.940 46.447 19.352 1.00 48.93 ? 41 ILE B CA 1 ATOM 1616 C C . ILE B 1 40 ? 17.675 45.881 18.697 1.00 57.60 ? 41 ILE B C 1 ATOM 1617 O O . ILE B 1 40 ? 17.750 45.293 17.611 1.00 56.90 ? 41 ILE B O 1 ATOM 1618 C CB . ILE B 1 40 ? 19.625 47.611 18.579 1.00 50.74 ? 41 ILE B CB 1 ATOM 1619 C CG1 . ILE B 1 40 ? 20.714 48.262 19.470 1.00 49.92 ? 41 ILE B CG1 1 ATOM 1620 C CG2 . ILE B 1 40 ? 18.605 48.654 18.103 1.00 50.15 ? 41 ILE B CG2 1 ATOM 1621 C CD1 . ILE B 1 40 ? 21.810 48.957 18.734 1.00 56.21 ? 41 ILE B CD1 1 ATOM 1622 N N . ASN B 1 41 ? 16.533 45.982 19.401 1.00 57.22 ? 42 ASN B N 1 ATOM 1623 C CA . ASN B 1 41 ? 15.278 45.434 18.873 1.00 58.88 ? 42 ASN B CA 1 ATOM 1624 C C . ASN B 1 41 ? 14.574 46.467 17.984 1.00 60.96 ? 42 ASN B C 1 ATOM 1625 O O . ASN B 1 41 ? 13.672 47.185 18.435 1.00 60.53 ? 42 ASN B O 1 ATOM 1626 C CB . ASN B 1 41 ? 14.380 44.905 20.016 1.00 68.11 ? 42 ASN B CB 1 ATOM 1627 C CG . ASN B 1 41 ? 13.079 44.258 19.574 1.00 102.67 ? 42 ASN B CG 1 ATOM 1628 O OD1 . ASN B 1 41 ? 12.029 44.461 20.198 1.00 100.53 ? 42 ASN B OD1 1 ATOM 1629 N ND2 . ASN B 1 41 ? 13.109 43.463 18.501 1.00 92.54 ? 42 ASN B ND2 1 ATOM 1630 N N . ALA B 1 42 ? 15.044 46.583 16.737 1.00 55.40 ? 43 ALA B N 1 ATOM 1631 C CA . ALA B 1 42 ? 14.484 47.557 15.803 1.00 54.48 ? 43 ALA B CA 1 ATOM 1632 C C . ALA B 1 42 ? 13.213 47.017 15.167 1.00 55.39 ? 43 ALA B C 1 ATOM 1633 O O . ALA B 1 42 ? 13.194 45.897 14.650 1.00 54.82 ? 43 ALA B O 1 ATOM 1634 C CB . ALA B 1 42 ? 15.507 47.926 14.737 1.00 55.07 ? 43 ALA B CB 1 ATOM 1635 N N . VAL B 1 43 ? 12.138 47.797 15.237 1.00 50.69 ? 44 VAL B N 1 ATOM 1636 C CA . VAL B 1 43 ? 10.878 47.390 14.602 1.00 50.00 ? 44 VAL B CA 1 ATOM 1637 C C . VAL B 1 43 ? 10.801 48.017 13.188 1.00 50.97 ? 44 VAL B C 1 ATOM 1638 O O . VAL B 1 43 ? 10.519 47.309 12.214 1.00 51.00 ? 44 VAL B O 1 ATOM 1639 C CB . VAL B 1 43 ? 9.611 47.564 15.500 1.00 53.55 ? 44 VAL B CB 1 ATOM 1640 C CG1 . VAL B 1 43 ? 9.861 47.024 16.910 1.00 52.98 ? 44 VAL B CG1 1 ATOM 1641 C CG2 . VAL B 1 43 ? 9.152 49.008 15.577 1.00 53.38 ? 44 VAL B CG2 1 ATOM 1642 N N . LEU B 1 44 ? 11.228 49.297 13.084 1.00 43.91 ? 45 LEU B N 1 ATOM 1643 C CA . LEU B 1 44 ? 11.300 50.065 11.856 1.00 42.95 ? 45 LEU B CA 1 ATOM 1644 C C . LEU B 1 44 ? 12.653 50.795 11.740 1.00 44.61 ? 45 LEU B C 1 ATOM 1645 O O . LEU B 1 44 ? 13.083 51.452 12.694 1.00 42.96 ? 45 LEU B O 1 ATOM 1646 C CB . LEU B 1 44 ? 10.139 51.082 11.831 1.00 43.13 ? 45 LEU B CB 1 ATOM 1647 C CG . LEU B 1 44 ? 9.964 51.917 10.542 1.00 48.47 ? 45 LEU B CG 1 ATOM 1648 C CD1 . LEU B 1 44 ? 9.588 51.038 9.319 1.00 47.68 ? 45 LEU B CD1 1 ATOM 1649 C CD2 . LEU B 1 44 ? 8.948 53.050 10.764 1.00 52.97 ? 45 LEU B CD2 1 ATOM 1650 N N . ILE B 1 45 ? 13.289 50.707 10.565 1.00 40.68 ? 46 ILE B N 1 ATOM 1651 C CA . ILE B 1 45 ? 14.541 51.420 10.253 1.00 41.46 ? 46 ILE B CA 1 ATOM 1652 C C . ILE B 1 45 ? 14.323 52.261 9.003 1.00 43.86 ? 46 ILE B C 1 ATOM 1653 O O . ILE B 1 45 ? 13.978 51.726 7.952 1.00 40.62 ? 46 ILE B O 1 ATOM 1654 C CB . ILE B 1 45 ? 15.782 50.492 10.120 1.00 44.62 ? 46 ILE B CB 1 ATOM 1655 C CG1 . ILE B 1 45 ? 16.041 49.748 11.440 1.00 44.91 ? 46 ILE B CG1 1 ATOM 1656 C CG2 . ILE B 1 45 ? 17.017 51.293 9.687 1.00 45.78 ? 46 ILE B CG2 1 ATOM 1657 C CD1 . ILE B 1 45 ? 16.914 48.567 11.285 1.00 47.24 ? 46 ILE B CD1 1 ATOM 1658 N N . THR B 1 46 ? 14.542 53.571 9.118 1.00 40.94 ? 47 THR B N 1 ATOM 1659 C CA . THR B 1 46 ? 14.338 54.498 8.002 1.00 39.93 ? 47 THR B CA 1 ATOM 1660 C C . THR B 1 46 ? 15.562 55.358 7.766 1.00 39.66 ? 47 THR B C 1 ATOM 1661 O O . THR B 1 46 ? 16.030 55.998 8.704 1.00 39.25 ? 47 THR B O 1 ATOM 1662 C CB . THR B 1 46 ? 13.123 55.395 8.357 1.00 46.84 ? 47 THR B CB 1 ATOM 1663 O OG1 . THR B 1 46 ? 11.977 54.582 8.546 1.00 50.80 ? 47 THR B OG1 1 ATOM 1664 C CG2 . THR B 1 46 ? 12.839 56.440 7.338 1.00 42.59 ? 47 THR B CG2 1 ATOM 1665 N N . TRP B 1 47 ? 16.012 55.467 6.515 1.00 34.69 ? 48 TRP B N 1 ATOM 1666 C CA . TRP B 1 47 ? 17.068 56.424 6.161 1.00 34.16 ? 48 TRP B CA 1 ATOM 1667 C C . TRP B 1 47 ? 16.406 57.634 5.497 1.00 36.21 ? 48 TRP B C 1 ATOM 1668 O O . TRP B 1 47 ? 15.644 57.450 4.561 1.00 34.81 ? 48 TRP B O 1 ATOM 1669 C CB . TRP B 1 47 ? 18.104 55.814 5.199 1.00 33.33 ? 48 TRP B CB 1 ATOM 1670 C CG . TRP B 1 47 ? 19.088 54.870 5.838 1.00 34.51 ? 48 TRP B CG 1 ATOM 1671 C CD1 . TRP B 1 47 ? 19.016 53.504 5.873 1.00 36.89 ? 48 TRP B CD1 1 ATOM 1672 C CD2 . TRP B 1 47 ? 20.327 55.227 6.475 1.00 34.47 ? 48 TRP B CD2 1 ATOM 1673 N NE1 . TRP B 1 47 ? 20.132 52.986 6.478 1.00 36.27 ? 48 TRP B NE1 1 ATOM 1674 C CE2 . TRP B 1 47 ? 20.946 54.021 6.883 1.00 37.96 ? 48 TRP B CE2 1 ATOM 1675 C CE3 . TRP B 1 47 ? 20.996 56.452 6.703 1.00 35.34 ? 48 TRP B CE3 1 ATOM 1676 C CZ2 . TRP B 1 47 ? 22.201 54.000 7.503 1.00 36.35 ? 48 TRP B CZ2 1 ATOM 1677 C CZ3 . TRP B 1 47 ? 22.222 56.430 7.357 1.00 36.55 ? 48 TRP B CZ3 1 ATOM 1678 C CH2 . TRP B 1 47 ? 22.809 55.215 7.749 1.00 36.85 ? 48 TRP B CH2 1 ATOM 1679 N N . ILE B 1 48 ? 16.676 58.841 5.973 1.00 34.01 ? 49 ILE B N 1 ATOM 1680 C CA . ILE B 1 48 ? 16.210 60.087 5.376 1.00 35.86 ? 49 ILE B CA 1 ATOM 1681 C C . ILE B 1 48 ? 17.451 60.757 4.784 1.00 39.39 ? 49 ILE B C 1 ATOM 1682 O O . ILE B 1 48 ? 18.413 61.029 5.506 1.00 38.05 ? 49 ILE B O 1 ATOM 1683 C CB . ILE B 1 48 ? 15.454 61.007 6.373 1.00 41.44 ? 49 ILE B CB 1 ATOM 1684 C CG1 . ILE B 1 48 ? 14.183 60.328 6.894 1.00 43.90 ? 49 ILE B CG1 1 ATOM 1685 C CG2 . ILE B 1 48 ? 15.077 62.335 5.713 1.00 43.91 ? 49 ILE B CG2 1 ATOM 1686 C CD1 . ILE B 1 48 ? 14.314 59.906 8.244 1.00 59.49 ? 49 ILE B CD1 1 ATOM 1687 N N . ILE B 1 49 ? 17.436 60.993 3.458 1.00 36.76 ? 50 ILE B N 1 ATOM 1688 C CA . ILE B 1 49 ? 18.550 61.574 2.704 1.00 34.74 ? 50 ILE B CA 1 ATOM 1689 C C . ILE B 1 49 ? 18.183 62.971 2.228 1.00 41.80 ? 50 ILE B C 1 ATOM 1690 O O . ILE B 1 49 ? 17.239 63.127 1.452 1.00 43.42 ? 50 ILE B O 1 ATOM 1691 C CB . ILE B 1 49 ? 18.951 60.628 1.568 1.00 36.37 ? 50 ILE B CB 1 ATOM 1692 C CG1 . ILE B 1 49 ? 19.297 59.240 2.128 1.00 36.60 ? 50 ILE B CG1 1 ATOM 1693 C CG2 . ILE B 1 49 ? 20.097 61.212 0.758 1.00 36.65 ? 50 ILE B CG2 1 ATOM 1694 C CD1 . ILE B 1 49 ? 18.674 58.114 1.438 1.00 39.82 ? 50 ILE B CD1 1 ATOM 1695 N N . LYS B 1 50 ? 18.926 63.978 2.708 1.00 37.69 ? 51 LYS B N 1 ATOM 1696 C CA . LYS B 1 50 ? 18.714 65.377 2.410 1.00 37.89 ? 51 LYS B CA 1 ATOM 1697 C C . LYS B 1 50 ? 19.913 66.003 1.677 1.00 44.48 ? 51 LYS B C 1 ATOM 1698 O O . LYS B 1 50 ? 21.043 65.861 2.111 1.00 43.87 ? 51 LYS B O 1 ATOM 1699 C CB . LYS B 1 50 ? 18.369 66.162 3.679 1.00 39.86 ? 51 LYS B CB 1 ATOM 1700 C CG . LYS B 1 50 ? 17.072 65.730 4.345 1.00 62.73 ? 51 LYS B CG 1 ATOM 1701 C CD . LYS B 1 50 ? 16.730 66.629 5.523 1.00 75.36 ? 51 LYS B CD 1 ATOM 1702 C CE . LYS B 1 50 ? 15.849 65.958 6.550 1.00 92.34 ? 51 LYS B CE 1 ATOM 1703 N NZ . LYS B 1 50 ? 16.622 65.074 7.478 1.00 101.03 ? 51 LYS B NZ 1 ATOM 1704 N N . HIS B 1 51 ? 19.642 66.641 0.521 1.00 42.25 ? 52 HIS B N 1 ATOM 1705 C CA . HIS B 1 51 ? 20.565 67.358 -0.350 1.00 42.27 ? 52 HIS B CA 1 ATOM 1706 C C . HIS B 1 51 ? 20.244 68.846 -0.219 1.00 47.96 ? 52 HIS B C 1 ATOM 1707 O O . HIS B 1 51 ? 19.159 69.199 0.259 1.00 47.59 ? 52 HIS B O 1 ATOM 1708 C CB . HIS B 1 51 ? 20.337 66.902 -1.791 1.00 43.35 ? 52 HIS B CB 1 ATOM 1709 C CG . HIS B 1 51 ? 21.349 67.377 -2.797 1.00 47.79 ? 52 HIS B CG 1 ATOM 1710 N ND1 . HIS B 1 51 ? 21.215 68.609 -3.451 1.00 49.76 ? 52 HIS B ND1 1 ATOM 1711 C CD2 . HIS B 1 51 ? 22.439 66.740 -3.291 1.00 49.35 ? 52 HIS B CD2 1 ATOM 1712 C CE1 . HIS B 1 51 ? 22.237 68.685 -4.283 1.00 48.95 ? 52 HIS B CE1 1 ATOM 1713 N NE2 . HIS B 1 51 ? 23.008 67.586 -4.215 1.00 49.36 ? 52 HIS B NE2 1 ATOM 1714 N N . ARG B 1 52 ? 21.196 69.720 -0.601 1.00 46.65 ? 53 ARG B N 1 ATOM 1715 C CA . ARG B 1 52 ? 21.055 71.182 -0.586 1.00 47.30 ? 53 ARG B CA 1 ATOM 1716 C C . ARG B 1 52 ? 19.966 71.615 -1.615 1.00 52.17 ? 53 ARG B C 1 ATOM 1717 O O . ARG B 1 52 ? 19.165 72.511 -1.340 1.00 52.87 ? 53 ARG B O 1 ATOM 1718 C CB . ARG B 1 52 ? 22.421 71.827 -0.918 1.00 48.58 ? 53 ARG B CB 1 ATOM 1719 C CG . ARG B 1 52 ? 22.607 73.237 -0.378 1.00 71.53 ? 53 ARG B CG 1 ATOM 1720 C CD . ARG B 1 52 ? 23.939 73.834 -0.800 1.00 103.56 ? 53 ARG B CD 1 ATOM 1721 N NE . ARG B 1 52 ? 23.781 75.232 -1.213 1.00 124.23 ? 53 ARG B NE 1 ATOM 1722 C CZ . ARG B 1 52 ? 24.714 75.951 -1.832 1.00 142.23 ? 53 ARG B CZ 1 ATOM 1723 N NH1 . ARG B 1 52 ? 25.875 75.398 -2.170 1.00 132.12 ? 53 ARG B NH1 1 ATOM 1724 N NH2 . ARG B 1 52 ? 24.478 77.215 -2.157 1.00 127.24 ? 53 ARG B NH2 1 ATOM 1725 N N . HIS B 1 53 ? 19.913 70.936 -2.757 1.00 47.94 ? 54 HIS B N 1 ATOM 1726 C CA . HIS B 1 53 ? 18.985 71.257 -3.828 1.00 49.04 ? 54 HIS B CA 1 ATOM 1727 C C . HIS B 1 53 ? 17.999 70.166 -4.149 1.00 47.97 ? 54 HIS B C 1 ATOM 1728 O O . HIS B 1 53 ? 16.807 70.448 -4.239 1.00 48.49 ? 54 HIS B O 1 ATOM 1729 C CB . HIS B 1 53 ? 19.744 71.735 -5.091 1.00 52.34 ? 54 HIS B CB 1 ATOM 1730 C CG . HIS B 1 53 ? 20.591 72.929 -4.796 1.00 58.35 ? 54 HIS B CG 1 ATOM 1731 N ND1 . HIS B 1 53 ? 20.034 74.100 -4.269 1.00 61.86 ? 54 HIS B ND1 1 ATOM 1732 C CD2 . HIS B 1 53 ? 21.936 73.069 -4.850 1.00 61.88 ? 54 HIS B CD2 1 ATOM 1733 C CE1 . HIS B 1 53 ? 21.051 74.920 -4.067 1.00 61.93 ? 54 HIS B CE1 1 ATOM 1734 N NE2 . HIS B 1 53 ? 22.219 74.342 -4.394 1.00 62.31 ? 54 HIS B NE2 1 ATOM 1735 N N . LEU B 1 54 ? 18.476 68.936 -4.327 1.00 40.37 ? 55 LEU B N 1 ATOM 1736 C CA . LEU B 1 54 ? 17.645 67.792 -4.687 1.00 37.80 ? 55 LEU B CA 1 ATOM 1737 C C . LEU B 1 54 ? 16.537 67.515 -3.689 1.00 39.57 ? 55 LEU B C 1 ATOM 1738 O O . LEU B 1 54 ? 16.690 67.797 -2.494 1.00 37.68 ? 55 LEU B O 1 ATOM 1739 C CB . LEU B 1 54 ? 18.480 66.532 -4.918 1.00 37.45 ? 55 LEU B CB 1 ATOM 1740 C CG . LEU B 1 54 ? 19.471 66.571 -6.070 1.00 42.96 ? 55 LEU B CG 1 ATOM 1741 C CD1 . LEU B 1 54 ? 20.307 65.308 -6.084 1.00 43.37 ? 55 LEU B CD1 1 ATOM 1742 C CD2 . LEU B 1 54 ? 18.753 66.749 -7.437 1.00 44.41 ? 55 LEU B CD2 1 ATOM 1743 N N . PRO B 1 55 ? 15.372 67.000 -4.150 1.00 36.39 ? 56 PRO B N 1 ATOM 1744 C CA . PRO B 1 55 ? 14.318 66.685 -3.166 1.00 35.83 ? 56 PRO B CA 1 ATOM 1745 C C . PRO B 1 55 ? 14.806 65.567 -2.249 1.00 41.91 ? 56 PRO B C 1 ATOM 1746 O O . PRO B 1 55 ? 15.569 64.693 -2.689 1.00 42.95 ? 56 PRO B O 1 ATOM 1747 C CB . PRO B 1 55 ? 13.113 66.262 -4.019 1.00 36.38 ? 56 PRO B CB 1 ATOM 1748 C CG . PRO B 1 55 ? 13.652 65.968 -5.348 1.00 40.69 ? 56 PRO B CG 1 ATOM 1749 C CD . PRO B 1 55 ? 14.987 66.612 -5.531 1.00 36.48 ? 56 PRO B CD 1 ATOM 1750 N N . SER B 1 56 ? 14.375 65.570 -1.001 1.00 39.03 ? 57 SER B N 1 ATOM 1751 C CA . SER B 1 56 ? 14.777 64.523 -0.076 1.00 40.11 ? 57 SER B CA 1 ATOM 1752 C C . SER B 1 56 ? 14.154 63.166 -0.434 1.00 46.05 ? 57 SER B C 1 ATOM 1753 O O . SER B 1 56 ? 13.152 63.119 -1.151 1.00 47.48 ? 57 SER B O 1 ATOM 1754 C CB . SER B 1 56 ? 14.470 64.932 1.359 1.00 42.89 ? 57 SER B CB 1 ATOM 1755 O OG . SER B 1 56 ? 13.167 64.540 1.739 1.00 51.34 ? 57 SER B OG 1 ATOM 1756 N N . CYS B 1 57 ? 14.800 62.073 -0.029 1.00 41.95 ? 58 CYS B N 1 ATOM 1757 C CA . CYS B 1 57 ? 14.282 60.741 -0.289 1.00 41.72 ? 58 CYS B CA 1 ATOM 1758 C C . CYS B 1 57 ? 14.500 59.819 0.904 1.00 45.96 ? 58 CYS B C 1 ATOM 1759 O O . CYS B 1 57 ? 15.180 60.199 1.862 1.00 42.98 ? 58 CYS B O 1 ATOM 1760 C CB . CYS B 1 57 ? 14.770 60.162 -1.613 1.00 42.57 ? 58 CYS B CB 1 ATOM 1761 S SG . CYS B 1 57 ? 16.449 59.486 -1.588 1.00 47.08 ? 58 CYS B SG 1 ATOM 1762 N N . THR B 1 58 ? 13.824 58.664 0.904 1.00 43.45 ? 59 THR B N 1 ATOM 1763 C CA . THR B 1 58 ? 13.791 57.755 2.033 1.00 42.36 ? 59 THR B CA 1 ATOM 1764 C C . THR B 1 58 ? 13.870 56.304 1.582 1.00 45.01 ? 59 THR B C 1 ATOM 1765 O O . THR B 1 58 ? 13.289 55.933 0.564 1.00 45.60 ? 59 THR B O 1 ATOM 1766 C CB . THR B 1 58 ? 12.456 58.040 2.794 1.00 50.46 ? 59 THR B CB 1 ATOM 1767 O OG1 . THR B 1 58 ? 12.505 59.348 3.343 1.00 59.17 ? 59 THR B OG1 1 ATOM 1768 C CG2 . THR B 1 58 ? 12.195 57.120 3.921 1.00 48.46 ? 59 THR B CG2 1 ATOM 1769 N N . ILE B 1 59 ? 14.585 55.488 2.347 1.00 39.50 ? 60 ILE B N 1 ATOM 1770 C CA . ILE B 1 59 ? 14.597 54.038 2.227 1.00 39.06 ? 60 ILE B CA 1 ATOM 1771 C C . ILE B 1 59 ? 14.189 53.553 3.643 1.00 41.70 ? 60 ILE B C 1 ATOM 1772 O O . ILE B 1 59 ? 14.709 54.066 4.637 1.00 40.50 ? 60 ILE B O 1 ATOM 1773 C CB . ILE B 1 59 ? 15.870 53.363 1.601 1.00 42.52 ? 60 ILE B CB 1 ATOM 1774 C CG1 . ILE B 1 59 ? 17.112 53.505 2.468 1.00 44.38 ? 60 ILE B CG1 1 ATOM 1775 C CG2 . ILE B 1 59 ? 16.152 53.878 0.192 1.00 41.76 ? 60 ILE B CG2 1 ATOM 1776 C CD1 . ILE B 1 59 ? 18.287 52.584 2.059 1.00 54.09 ? 60 ILE B CD1 1 ATOM 1777 N N . ALA B 1 60 ? 13.164 52.709 3.732 1.00 38.10 ? 61 ALA B N 1 ATOM 1778 C CA . ALA B 1 60 ? 12.641 52.219 5.008 1.00 38.12 ? 61 ALA B CA 1 ATOM 1779 C C . ALA B 1 60 ? 12.455 50.718 4.990 1.00 44.55 ? 61 ALA B C 1 ATOM 1780 O O . ALA B 1 60 ? 12.182 50.128 3.938 1.00 44.13 ? 61 ALA B O 1 ATOM 1781 C CB . ALA B 1 60 ? 11.323 52.891 5.333 1.00 38.82 ? 61 ALA B CB 1 ATOM 1782 N N . TYR B 1 61 ? 12.618 50.092 6.157 1.00 42.26 ? 62 TYR B N 1 ATOM 1783 C CA . TYR B 1 61 ? 12.451 48.660 6.306 1.00 43.12 ? 62 TYR B CA 1 ATOM 1784 C C . TYR B 1 61 ? 11.687 48.359 7.571 1.00 49.59 ? 62 TYR B C 1 ATOM 1785 O O . TYR B 1 61 ? 12.075 48.822 8.642 1.00 49.24 ? 62 TYR B O 1 ATOM 1786 C CB . TYR B 1 61 ? 13.799 47.919 6.266 1.00 45.34 ? 62 TYR B CB 1 ATOM 1787 C CG . TYR B 1 61 ? 13.644 46.459 5.906 1.00 48.61 ? 62 TYR B CG 1 ATOM 1788 C CD1 . TYR B 1 61 ? 13.291 45.511 6.876 1.00 49.73 ? 62 TYR B CD1 1 ATOM 1789 C CD2 . TYR B 1 61 ? 13.861 46.016 4.604 1.00 50.35 ? 62 TYR B CD2 1 ATOM 1790 C CE1 . TYR B 1 61 ? 13.117 44.167 6.546 1.00 50.36 ? 62 TYR B CE1 1 ATOM 1791 C CE2 . TYR B 1 61 ? 13.699 44.671 4.262 1.00 52.79 ? 62 TYR B CE2 1 ATOM 1792 C CZ . TYR B 1 61 ? 13.327 43.749 5.236 1.00 62.28 ? 62 TYR B CZ 1 ATOM 1793 O OH . TYR B 1 61 ? 13.162 42.420 4.897 1.00 66.92 ? 62 TYR B OH 1 ATOM 1794 N N . ASN B 1 62 ? 10.558 47.637 7.451 1.00 50.32 ? 63 ASN B N 1 ATOM 1795 C CA . ASN B 1 62 ? 9.733 47.213 8.589 1.00 52.23 ? 63 ASN B CA 1 ATOM 1796 C C . ASN B 1 62 ? 10.226 45.820 8.917 1.00 62.23 ? 63 ASN B C 1 ATOM 1797 O O . ASN B 1 62 ? 10.018 44.903 8.123 1.00 63.48 ? 63 ASN B O 1 ATOM 1798 C CB . ASN B 1 62 ? 8.251 47.163 8.217 1.00 53.35 ? 63 ASN B CB 1 ATOM 1799 C CG . ASN B 1 62 ? 7.336 47.187 9.420 1.00 75.47 ? 63 ASN B CG 1 ATOM 1800 O OD1 . ASN B 1 62 ? 7.325 46.260 10.239 1.00 67.81 ? 63 ASN B OD1 1 ATOM 1801 N ND2 . ASN B 1 62 ? 6.553 48.263 9.559 1.00 63.05 ? 63 ASN B ND2 1 ATOM 1802 N N . LEU B 1 63 ? 10.985 45.672 10.014 1.00 60.87 ? 64 LEU B N 1 ATOM 1803 C CA . LEU B 1 63 ? 11.567 44.380 10.412 1.00 60.99 ? 64 LEU B CA 1 ATOM 1804 C C . LEU B 1 63 ? 10.512 43.416 10.972 1.00 65.91 ? 64 LEU B C 1 ATOM 1805 O O . LEU B 1 63 ? 10.662 42.197 10.854 1.00 65.57 ? 64 LEU B O 1 ATOM 1806 C CB . LEU B 1 63 ? 12.741 44.564 11.394 1.00 60.57 ? 64 LEU B CB 1 ATOM 1807 C CG . LEU B 1 63 ? 14.052 45.063 10.776 1.00 64.12 ? 64 LEU B CG 1 ATOM 1808 C CD1 . LEU B 1 63 ? 14.062 46.557 10.694 1.00 63.79 ? 64 LEU B CD1 1 ATOM 1809 C CD2 . LEU B 1 63 ? 15.231 44.638 11.598 1.00 63.87 ? 64 LEU B CD2 1 ATOM 1810 N N . ASP B 1 64 ? 9.434 43.978 11.543 1.00 62.70 ? 65 ASP B N 1 ATOM 1811 C CA . ASP B 1 64 ? 8.288 43.249 12.085 1.00 64.07 ? 65 ASP B CA 1 ATOM 1812 C C . ASP B 1 64 ? 7.540 42.562 10.907 1.00 71.39 ? 65 ASP B C 1 ATOM 1813 O O . ASP B 1 64 ? 7.494 41.330 10.854 1.00 71.75 ? 65 ASP B O 1 ATOM 1814 C CB . ASP B 1 64 ? 7.339 44.224 12.835 1.00 66.39 ? 65 ASP B CB 1 ATOM 1815 C CG . ASP B 1 64 ? 7.284 44.186 14.371 1.00 81.67 ? 65 ASP B CG 1 ATOM 1816 O OD1 . ASP B 1 64 ? 8.169 43.542 14.991 1.00 79.95 ? 65 ASP B OD1 1 ATOM 1817 O OD2 . ASP B 1 64 ? 6.384 44.846 14.950 1.00 92.84 ? 65 ASP B OD2 1 ATOM 1818 N N . LYS B 1 65 ? 7.025 43.366 9.932 1.00 68.77 ? 66 LYS B N 1 ATOM 1819 C CA . LYS B 1 65 ? 6.246 42.907 8.764 1.00 68.00 ? 66 LYS B CA 1 ATOM 1820 C C . LYS B 1 65 ? 7.081 42.448 7.574 1.00 72.05 ? 66 LYS B C 1 ATOM 1821 O O . LYS B 1 65 ? 6.502 42.045 6.566 1.00 73.01 ? 66 LYS B O 1 ATOM 1822 C CB . LYS B 1 65 ? 5.234 43.975 8.306 1.00 69.47 ? 66 LYS B CB 1 ATOM 1823 C CG . LYS B 1 65 ? 4.393 44.591 9.411 1.00 83.15 ? 66 LYS B CG 1 ATOM 1824 C CD . LYS B 1 65 ? 3.557 45.714 8.856 1.00 98.20 ? 66 LYS B CD 1 ATOM 1825 C CE . LYS B 1 65 ? 2.751 46.402 9.944 1.00 117.92 ? 66 LYS B CE 1 ATOM 1826 N NZ . LYS B 1 65 ? 1.853 47.468 9.411 1.00 130.09 ? 66 LYS B NZ 1 ATOM 1827 N N . LYS B 1 66 ? 8.424 42.489 7.683 1.00 67.65 ? 67 LYS B N 1 ATOM 1828 C CA . LYS B 1 66 ? 9.382 42.111 6.623 1.00 67.35 ? 67 LYS B CA 1 ATOM 1829 C C . LYS B 1 66 ? 9.143 42.820 5.251 1.00 70.33 ? 67 LYS B C 1 ATOM 1830 O O . LYS B 1 66 ? 9.404 42.255 4.183 1.00 69.25 ? 67 LYS B O 1 ATOM 1831 C CB . LYS B 1 66 ? 9.557 40.587 6.519 1.00 69.54 ? 67 LYS B CB 1 ATOM 1832 C CG . LYS B 1 66 ? 10.296 39.978 7.708 1.00 84.63 ? 67 LYS B CG 1 ATOM 1833 C CD . LYS B 1 66 ? 10.700 38.528 7.447 1.00 93.47 ? 67 LYS B CD 1 ATOM 1834 C CE . LYS B 1 66 ? 11.414 37.913 8.624 1.00 107.13 ? 67 LYS B CE 1 ATOM 1835 N NZ . LYS B 1 66 ? 11.644 36.460 8.420 1.00 119.57 ? 67 LYS B NZ 1 ATOM 1836 N N . THR B 1 67 ? 8.661 44.082 5.309 1.00 65.47 ? 68 THR B N 1 ATOM 1837 C CA . THR B 1 67 ? 8.380 44.895 4.125 1.00 63.80 ? 68 THR B CA 1 ATOM 1838 C C . THR B 1 67 ? 9.336 46.087 4.017 1.00 64.00 ? 68 THR B C 1 ATOM 1839 O O . THR B 1 67 ? 9.919 46.514 5.017 1.00 63.35 ? 68 THR B O 1 ATOM 1840 C CB . THR B 1 67 ? 6.913 45.325 4.103 1.00 69.34 ? 68 THR B CB 1 ATOM 1841 O OG1 . THR B 1 67 ? 6.630 46.122 5.255 1.00 67.87 ? 68 THR B OG1 1 ATOM 1842 C CG2 . THR B 1 67 ? 5.961 44.148 4.010 1.00 68.20 ? 68 THR B CG2 1 ATOM 1843 N N . ASN B 1 68 ? 9.519 46.603 2.793 1.00 56.74 ? 69 ASN B N 1 ATOM 1844 C CA . ASN B 1 68 ? 10.381 47.748 2.564 1.00 54.07 ? 69 ASN B CA 1 ATOM 1845 C C . ASN B 1 68 ? 9.807 48.711 1.524 1.00 52.12 ? 69 ASN B C 1 ATOM 1846 O O . ASN B 1 68 ? 8.996 48.329 0.696 1.00 50.57 ? 69 ASN B O 1 ATOM 1847 C CB . ASN B 1 68 ? 11.777 47.311 2.205 1.00 52.87 ? 69 ASN B CB 1 ATOM 1848 C CG . ASN B 1 68 ? 11.919 46.699 0.852 1.00 89.74 ? 69 ASN B CG 1 ATOM 1849 O OD1 . ASN B 1 68 ? 11.212 45.746 0.488 1.00 83.78 ? 69 ASN B OD1 1 ATOM 1850 N ND2 . ASN B 1 68 ? 12.886 47.249 0.121 1.00 99.98 ? 69 ASN B ND2 1 ATOM 1851 N N . GLU B 1 69 ? 10.213 49.965 1.616 1.00 44.82 ? 70 GLU B N 1 ATOM 1852 C CA . GLU B 1 69 ? 9.812 51.046 0.747 1.00 43.52 ? 70 GLU B CA 1 ATOM 1853 C C . GLU B 1 69 ? 11.055 51.831 0.345 1.00 44.95 ? 70 GLU B C 1 ATOM 1854 O O . GLU B 1 69 ? 12.033 51.898 1.098 1.00 45.34 ? 70 GLU B O 1 ATOM 1855 C CB . GLU B 1 69 ? 8.897 52.025 1.506 1.00 45.17 ? 70 GLU B CB 1 ATOM 1856 C CG . GLU B 1 69 ? 7.623 51.478 2.115 1.00 57.60 ? 70 GLU B CG 1 ATOM 1857 C CD . GLU B 1 69 ? 6.939 52.462 3.043 1.00 79.42 ? 70 GLU B CD 1 ATOM 1858 O OE1 . GLU B 1 69 ? 7.623 53.342 3.614 1.00 76.10 ? 70 GLU B OE1 1 ATOM 1859 O OE2 . GLU B 1 69 ? 5.710 52.338 3.218 1.00 81.60 ? 70 GLU B OE2 1 ATOM 1860 N N . THR B 1 70 ? 10.990 52.480 -0.802 1.00 38.90 ? 71 THR B N 1 ATOM 1861 C CA . THR B 1 70 ? 12.051 53.357 -1.293 1.00 37.84 ? 71 THR B CA 1 ATOM 1862 C C . THR B 1 70 ? 11.487 54.452 -2.182 1.00 40.41 ? 71 THR B C 1 ATOM 1863 O O . THR B 1 70 ? 10.669 54.174 -3.056 1.00 39.30 ? 71 THR B O 1 ATOM 1864 C CB . THR B 1 70 ? 13.214 52.598 -1.988 1.00 39.81 ? 71 THR B CB 1 ATOM 1865 O OG1 . THR B 1 70 ? 14.159 53.538 -2.500 1.00 40.07 ? 71 THR B OG1 1 ATOM 1866 C CG2 . THR B 1 70 ? 12.759 51.685 -3.118 1.00 34.23 ? 71 THR B CG2 1 ATOM 1867 N N . SER B 1 71 ? 11.929 55.685 -1.947 1.00 35.79 ? 72 SER B N 1 ATOM 1868 C CA . SER B 1 71 ? 11.630 56.816 -2.789 1.00 35.03 ? 72 SER B CA 1 ATOM 1869 C C . SER B 1 71 ? 12.967 57.347 -3.377 1.00 42.07 ? 72 SER B C 1 ATOM 1870 O O . SER B 1 71 ? 13.011 58.463 -3.885 1.00 42.48 ? 72 SER B O 1 ATOM 1871 C CB . SER B 1 71 ? 10.828 57.872 -2.030 1.00 36.64 ? 72 SER B CB 1 ATOM 1872 O OG . SER B 1 71 ? 11.528 58.540 -1.000 1.00 46.51 ? 72 SER B OG 1 ATOM 1873 N N . CYS B 1 72 ? 14.042 56.514 -3.372 1.00 41.02 ? 73 CYS B N 1 ATOM 1874 C CA . CYS B 1 72 ? 15.388 56.912 -3.855 1.00 42.10 ? 73 CYS B CA 1 ATOM 1875 C C . CYS B 1 72 ? 15.751 56.238 -5.160 1.00 45.37 ? 73 CYS B C 1 ATOM 1876 O O . CYS B 1 72 ? 16.933 56.033 -5.415 1.00 45.64 ? 73 CYS B O 1 ATOM 1877 C CB . CYS B 1 72 ? 16.470 56.652 -2.794 1.00 42.67 ? 73 CYS B CB 1 ATOM 1878 S SG . CYS B 1 72 ? 16.207 57.483 -1.209 1.00 47.16 ? 73 CYS B SG 1 ATOM 1879 N N . LEU B 1 73 ? 14.774 55.850 -5.972 1.00 42.27 ? 74 LEU B N 1 ATOM 1880 C CA . LEU B 1 73 ? 15.088 55.156 -7.229 1.00 41.10 ? 74 LEU B CA 1 ATOM 1881 C C . LEU B 1 73 ? 15.851 56.074 -8.185 1.00 47.42 ? 74 LEU B C 1 ATOM 1882 O O . LEU B 1 73 ? 15.569 57.284 -8.232 1.00 48.52 ? 74 LEU B O 1 ATOM 1883 C CB . LEU B 1 73 ? 13.836 54.544 -7.898 1.00 39.92 ? 74 LEU B CB 1 ATOM 1884 C CG . LEU B 1 73 ? 13.032 53.520 -7.095 1.00 42.44 ? 74 LEU B CG 1 ATOM 1885 C CD1 . LEU B 1 73 ? 11.889 52.967 -7.916 1.00 42.34 ? 74 LEU B CD1 1 ATOM 1886 C CD2 . LEU B 1 73 ? 13.879 52.387 -6.671 1.00 41.84 ? 74 LEU B CD2 1 ATOM 1887 N N . GLY B 1 74 ? 16.845 55.502 -8.864 1.00 44.06 ? 75 GLY B N 1 ATOM 1888 C CA . GLY B 1 74 ? 17.695 56.204 -9.820 1.00 44.41 ? 75 GLY B CA 1 ATOM 1889 C C . GLY B 1 74 ? 18.800 57.038 -9.206 1.00 48.51 ? 75 GLY B C 1 ATOM 1890 O O . GLY B 1 74 ? 19.432 57.845 -9.896 1.00 51.11 ? 75 GLY B O 1 ATOM 1891 N N . ARG B 1 75 ? 19.039 56.864 -7.912 1.00 41.40 ? 76 ARG B N 1 ATOM 1892 C CA . ARG B 1 75 ? 20.077 57.642 -7.241 1.00 40.02 ? 76 ARG B CA 1 ATOM 1893 C C . ARG B 1 75 ? 21.205 56.729 -6.815 1.00 45.03 ? 76 ARG B C 1 ATOM 1894 O O . ARG B 1 75 ? 22.159 57.193 -6.196 1.00 46.14 ? 76 ARG B O 1 ATOM 1895 C CB . ARG B 1 75 ? 19.487 58.395 -6.026 1.00 36.42 ? 76 ARG B CB 1 ATOM 1896 C CG . ARG B 1 75 ? 18.330 59.342 -6.401 1.00 36.37 ? 76 ARG B CG 1 ATOM 1897 C CD . ARG B 1 75 ? 18.080 60.392 -5.355 1.00 41.02 ? 76 ARG B CD 1 ATOM 1898 N NE . ARG B 1 75 ? 19.330 61.018 -4.897 1.00 55.67 ? 76 ARG B NE 1 ATOM 1899 C CZ . ARG B 1 75 ? 19.425 61.837 -3.853 1.00 71.89 ? 76 ARG B CZ 1 ATOM 1900 N NH1 . ARG B 1 75 ? 18.351 62.134 -3.130 1.00 59.11 ? 76 ARG B NH1 1 ATOM 1901 N NH2 . ARG B 1 75 ? 20.597 62.358 -3.518 1.00 61.40 ? 76 ARG B NH2 1 ATOM 1902 N N . ASN B 1 76 ? 21.096 55.422 -7.117 1.00 41.64 ? 77 ASN B N 1 ATOM 1903 C CA . ASN B 1 76 ? 22.083 54.413 -6.705 1.00 41.90 ? 77 ASN B CA 1 ATOM 1904 C C . ASN B 1 76 ? 22.221 54.214 -5.172 1.00 46.41 ? 77 ASN B C 1 ATOM 1905 O O . ASN B 1 76 ? 23.268 53.760 -4.690 1.00 48.17 ? 77 ASN B O 1 ATOM 1906 C CB . ASN B 1 76 ? 23.421 54.656 -7.377 1.00 43.96 ? 77 ASN B CB 1 ATOM 1907 C CG . ASN B 1 76 ? 23.571 53.998 -8.709 1.00 77.22 ? 77 ASN B CG 1 ATOM 1908 O OD1 . ASN B 1 76 ? 23.233 52.824 -8.908 1.00 68.90 ? 77 ASN B OD1 1 ATOM 1909 N ND2 . ASN B 1 76 ? 24.128 54.723 -9.644 1.00 88.06 ? 77 ASN B ND2 1 ATOM 1910 N N . ILE B 1 77 ? 21.140 54.531 -4.418 1.00 39.84 ? 78 ILE B N 1 ATOM 1911 C CA . ILE B 1 77 ? 21.032 54.371 -2.974 1.00 38.08 ? 78 ILE B CA 1 ATOM 1912 C C . ILE B 1 77 ? 20.151 53.152 -2.666 1.00 46.60 ? 78 ILE B C 1 ATOM 1913 O O . ILE B 1 77 ? 18.963 53.150 -3.016 1.00 48.06 ? 78 ILE B O 1 ATOM 1914 C CB . ILE B 1 77 ? 20.476 55.641 -2.312 1.00 39.61 ? 78 ILE B CB 1 ATOM 1915 C CG1 . ILE B 1 77 ? 21.389 56.860 -2.584 1.00 37.91 ? 78 ILE B CG1 1 ATOM 1916 C CG2 . ILE B 1 77 ? 20.243 55.397 -0.796 1.00 40.66 ? 78 ILE B CG2 1 ATOM 1917 C CD1 . ILE B 1 77 ? 20.752 58.207 -2.276 1.00 35.59 ? 78 ILE B CD1 1 ATOM 1918 N N . THR B 1 78 ? 20.730 52.114 -2.013 1.00 43.96 ? 79 THR B N 1 ATOM 1919 C CA . THR B 1 78 ? 20.032 50.869 -1.649 1.00 43.19 ? 79 THR B CA 1 ATOM 1920 C C . THR B 1 78 ? 20.492 50.388 -0.271 1.00 44.52 ? 79 THR B C 1 ATOM 1921 O O . THR B 1 78 ? 21.441 50.937 0.266 1.00 41.99 ? 79 THR B O 1 ATOM 1922 C CB . THR B 1 78 ? 20.359 49.761 -2.681 1.00 49.37 ? 79 THR B CB 1 ATOM 1923 O OG1 . THR B 1 78 ? 21.714 49.364 -2.539 1.00 50.08 ? 79 THR B OG1 1 ATOM 1924 C CG2 . THR B 1 78 ? 20.058 50.152 -4.163 1.00 46.73 ? 79 THR B CG2 1 ATOM 1925 N N . TRP B 1 79 ? 19.834 49.334 0.268 1.00 42.25 ? 80 TRP B N 1 ATOM 1926 C CA . TRP B 1 79 ? 20.234 48.607 1.477 1.00 41.12 ? 80 TRP B CA 1 ATOM 1927 C C . TRP B 1 79 ? 21.438 47.766 1.019 1.00 46.06 ? 80 TRP B C 1 ATOM 1928 O O . TRP B 1 79 ? 21.355 47.139 -0.045 1.00 44.02 ? 80 TRP B O 1 ATOM 1929 C CB . TRP B 1 79 ? 19.104 47.662 1.953 1.00 38.38 ? 80 TRP B CB 1 ATOM 1930 C CG . TRP B 1 79 ? 17.960 48.389 2.601 1.00 38.34 ? 80 TRP B CG 1 ATOM 1931 C CD1 . TRP B 1 79 ? 16.717 48.592 2.078 1.00 40.66 ? 80 TRP B CD1 1 ATOM 1932 C CD2 . TRP B 1 79 ? 17.969 49.043 3.882 1.00 37.77 ? 80 TRP B CD2 1 ATOM 1933 N NE1 . TRP B 1 79 ? 15.946 49.316 2.956 1.00 39.63 ? 80 TRP B NE1 1 ATOM 1934 C CE2 . TRP B 1 79 ? 16.689 49.614 4.069 1.00 41.33 ? 80 TRP B CE2 1 ATOM 1935 C CE3 . TRP B 1 79 ? 18.926 49.185 4.901 1.00 38.53 ? 80 TRP B CE3 1 ATOM 1936 C CZ2 . TRP B 1 79 ? 16.346 50.333 5.230 1.00 40.67 ? 80 TRP B CZ2 1 ATOM 1937 C CZ3 . TRP B 1 79 ? 18.574 49.876 6.059 1.00 40.13 ? 80 TRP B CZ3 1 ATOM 1938 C CH2 . TRP B 1 79 ? 17.297 50.432 6.219 1.00 40.80 ? 80 TRP B CH2 1 ATOM 1939 N N . ALA B 1 80 ? 22.555 47.767 1.793 1.00 44.38 ? 81 ALA B N 1 ATOM 1940 C CA . ALA B 1 80 ? 23.744 46.973 1.463 1.00 44.14 ? 81 ALA B CA 1 ATOM 1941 C C . ALA B 1 80 ? 23.362 45.483 1.324 1.00 51.20 ? 81 ALA B C 1 ATOM 1942 O O . ALA B 1 80 ? 23.833 44.800 0.413 1.00 51.67 ? 81 ALA B O 1 ATOM 1943 C CB . ALA B 1 80 ? 24.805 47.156 2.520 1.00 44.43 ? 81 ALA B CB 1 ATOM 1944 N N . SER B 1 81 ? 22.462 45.021 2.198 1.00 49.74 ? 82 SER B N 1 ATOM 1945 C CA . SER B 1 81 ? 21.851 43.683 2.250 1.00 50.69 ? 82 SER B CA 1 ATOM 1946 C C . SER B 1 81 ? 20.542 43.846 3.061 1.00 56.36 ? 82 SER B C 1 ATOM 1947 O O . SER B 1 81 ? 20.315 44.921 3.625 1.00 56.25 ? 82 SER B O 1 ATOM 1948 C CB . SER B 1 81 ? 22.791 42.690 2.942 1.00 53.91 ? 82 SER B CB 1 ATOM 1949 O OG . SER B 1 81 ? 23.127 43.087 4.265 1.00 59.86 ? 82 SER B OG 1 ATOM 1950 N N . THR B 1 82 ? 19.696 42.805 3.123 1.00 54.08 ? 83 THR B N 1 ATOM 1951 C CA . THR B 1 82 ? 18.463 42.849 3.914 1.00 54.92 ? 83 THR B CA 1 ATOM 1952 C C . THR B 1 82 ? 18.795 43.205 5.371 1.00 61.86 ? 83 THR B C 1 ATOM 1953 O O . THR B 1 82 ? 19.606 42.525 5.998 1.00 61.95 ? 83 THR B O 1 ATOM 1954 C CB . THR B 1 82 ? 17.672 41.535 3.787 1.00 62.11 ? 83 THR B CB 1 ATOM 1955 O OG1 . THR B 1 82 ? 17.388 41.315 2.413 1.00 59.57 ? 83 THR B OG1 1 ATOM 1956 C CG2 . THR B 1 82 ? 16.359 41.560 4.575 1.00 60.60 ? 83 THR B CG2 1 ATOM 1957 N N . PRO B 1 83 ? 18.213 44.296 5.903 1.00 61.26 ? 84 PRO B N 1 ATOM 1958 C CA . PRO B 1 83 ? 18.529 44.690 7.281 1.00 62.00 ? 84 PRO B CA 1 ATOM 1959 C C . PRO B 1 83 ? 17.963 43.807 8.399 1.00 68.83 ? 84 PRO B C 1 ATOM 1960 O O . PRO B 1 83 ? 16.787 43.419 8.395 1.00 68.02 ? 84 PRO B O 1 ATOM 1961 C CB . PRO B 1 83 ? 18.032 46.129 7.371 1.00 63.24 ? 84 PRO B CB 1 ATOM 1962 C CG . PRO B 1 83 ? 17.003 46.227 6.370 1.00 67.18 ? 84 PRO B CG 1 ATOM 1963 C CD . PRO B 1 83 ? 17.261 45.232 5.282 1.00 62.95 ? 84 PRO B CD 1 ATOM 1964 N N . ASP B 1 84 ? 18.838 43.495 9.373 1.00 66.82 ? 85 ASP B N 1 ATOM 1965 C CA . ASP B 1 84 ? 18.519 42.722 10.571 1.00 66.13 ? 85 ASP B CA 1 ATOM 1966 C C . ASP B 1 84 ? 19.255 43.311 11.816 1.00 68.21 ? 85 ASP B C 1 ATOM 1967 O O . ASP B 1 84 ? 18.704 44.185 12.494 1.00 66.99 ? 85 ASP B O 1 ATOM 1968 C CB . ASP B 1 84 ? 18.776 41.209 10.346 1.00 68.24 ? 85 ASP B CB 1 ATOM 1969 C CG . ASP B 1 84 ? 18.385 40.297 11.513 1.00 82.90 ? 85 ASP B CG 1 ATOM 1970 O OD1 . ASP B 1 84 ? 17.469 40.679 12.299 1.00 83.74 ? 85 ASP B OD1 1 ATOM 1971 O OD2 . ASP B 1 84 ? 18.984 39.199 11.635 1.00 88.19 ? 85 ASP B OD2 1 ATOM 1972 N N . HIS B 1 85 ? 20.500 42.861 12.083 1.00 64.97 ? 86 HIS B N 1 ATOM 1973 C CA . HIS B 1 85 ? 21.312 43.317 13.213 1.00 64.66 ? 86 HIS B CA 1 ATOM 1974 C C . HIS B 1 85 ? 22.386 44.338 12.819 1.00 61.55 ? 86 HIS B C 1 ATOM 1975 O O . HIS B 1 85 ? 22.945 45.007 13.692 1.00 59.78 ? 86 HIS B O 1 ATOM 1976 C CB . HIS B 1 85 ? 21.912 42.113 13.965 1.00 67.18 ? 86 HIS B CB 1 ATOM 1977 C CG . HIS B 1 85 ? 20.871 41.196 14.545 1.00 71.87 ? 86 HIS B CG 1 ATOM 1978 N ND1 . HIS B 1 85 ? 19.750 41.697 15.220 1.00 74.06 ? 86 HIS B ND1 1 ATOM 1979 C CD2 . HIS B 1 85 ? 20.811 39.841 14.543 1.00 74.66 ? 86 HIS B CD2 1 ATOM 1980 C CE1 . HIS B 1 85 ? 19.051 40.637 15.597 1.00 74.13 ? 86 HIS B CE1 1 ATOM 1981 N NE2 . HIS B 1 85 ? 19.645 39.496 15.213 1.00 74.79 ? 86 HIS B NE2 1 ATOM 1982 N N . SER B 1 86 ? 22.645 44.465 11.495 1.00 54.79 ? 87 SER B N 1 ATOM 1983 C CA . SER B 1 86 ? 23.615 45.387 10.900 1.00 52.79 ? 87 SER B CA 1 ATOM 1984 C C . SER B 1 86 ? 22.997 46.205 9.731 1.00 52.74 ? 87 SER B C 1 ATOM 1985 O O . SER B 1 86 ? 23.482 46.084 8.590 1.00 52.51 ? 87 SER B O 1 ATOM 1986 C CB . SER B 1 86 ? 24.857 44.625 10.437 1.00 55.05 ? 87 SER B CB 1 ATOM 1987 O OG . SER B 1 86 ? 25.586 44.091 11.528 1.00 59.25 ? 87 SER B OG 1 ATOM 1988 N N . PRO B 1 87 ? 21.938 47.042 9.975 1.00 45.70 ? 88 PRO B N 1 ATOM 1989 C CA . PRO B 1 87 ? 21.367 47.843 8.870 1.00 44.35 ? 88 PRO B CA 1 ATOM 1990 C C . PRO B 1 87 ? 22.400 48.821 8.294 1.00 44.70 ? 88 PRO B C 1 ATOM 1991 O O . PRO B 1 87 ? 23.100 49.532 9.031 1.00 43.65 ? 88 PRO B O 1 ATOM 1992 C CB . PRO B 1 87 ? 20.181 48.543 9.527 1.00 45.79 ? 88 PRO B CB 1 ATOM 1993 C CG . PRO B 1 87 ? 20.510 48.574 10.948 1.00 49.69 ? 88 PRO B CG 1 ATOM 1994 C CD . PRO B 1 87 ? 21.233 47.325 11.239 1.00 45.56 ? 88 PRO B CD 1 ATOM 1995 N N . GLU B 1 88 ? 22.547 48.787 6.975 1.00 39.20 ? 89 GLU B N 1 ATOM 1996 C CA . GLU B 1 88 ? 23.560 49.547 6.260 1.00 37.75 ? 89 GLU B CA 1 ATOM 1997 C C . GLU B 1 88 ? 23.062 50.058 4.911 1.00 40.10 ? 89 GLU B C 1 ATOM 1998 O O . GLU B 1 88 ? 22.522 49.297 4.090 1.00 38.83 ? 89 GLU B O 1 ATOM 1999 C CB . GLU B 1 88 ? 24.790 48.616 6.060 1.00 38.98 ? 89 GLU B CB 1 ATOM 2000 C CG . GLU B 1 88 ? 26.104 49.309 5.748 1.00 41.79 ? 89 GLU B CG 1 ATOM 2001 C CD . GLU B 1 88 ? 27.301 48.391 5.752 1.00 61.81 ? 89 GLU B CD 1 ATOM 2002 O OE1 . GLU B 1 88 ? 27.171 47.224 5.306 1.00 57.45 ? 89 GLU B OE1 1 ATOM 2003 O OE2 . GLU B 1 88 ? 28.379 48.847 6.198 1.00 64.92 ? 89 GLU B OE2 1 ATOM 2004 N N . LEU B 1 89 ? 23.276 51.350 4.674 1.00 37.98 ? 90 LEU B N 1 ATOM 2005 C CA . LEU B 1 89 ? 22.936 51.986 3.403 1.00 38.19 ? 90 LEU B CA 1 ATOM 2006 C C . LEU B 1 89 ? 24.176 51.870 2.517 1.00 43.91 ? 90 LEU B C 1 ATOM 2007 O O . LEU B 1 89 ? 25.302 52.033 2.986 1.00 45.68 ? 90 LEU B O 1 ATOM 2008 C CB . LEU B 1 89 ? 22.576 53.466 3.635 1.00 38.52 ? 90 LEU B CB 1 ATOM 2009 C CG . LEU B 1 89 ? 22.093 54.278 2.429 1.00 43.27 ? 90 LEU B CG 1 ATOM 2010 C CD1 . LEU B 1 89 ? 20.987 55.199 2.816 1.00 42.92 ? 90 LEU B CD1 1 ATOM 2011 C CD2 . LEU B 1 89 ? 23.215 55.102 1.833 1.00 45.53 ? 90 LEU B CD2 1 ATOM 2012 N N . GLN B 1 90 ? 23.963 51.598 1.250 1.00 39.97 ? 91 GLN B N 1 ATOM 2013 C CA . GLN B 1 90 ? 24.994 51.509 0.239 1.00 39.75 ? 91 GLN B CA 1 ATOM 2014 C C . GLN B 1 90 ? 24.753 52.534 -0.903 1.00 46.28 ? 91 GLN B C 1 ATOM 2015 O O . GLN B 1 90 ? 23.632 52.634 -1.421 1.00 45.45 ? 91 GLN B O 1 ATOM 2016 C CB . GLN B 1 90 ? 24.976 50.111 -0.373 1.00 40.48 ? 91 GLN B CB 1 ATOM 2017 C CG . GLN B 1 90 ? 26.151 49.833 -1.296 1.00 44.22 ? 91 GLN B CG 1 ATOM 2018 C CD . GLN B 1 90 ? 25.999 48.488 -1.946 1.00 56.75 ? 91 GLN B CD 1 ATOM 2019 O OE1 . GLN B 1 90 ? 25.363 48.356 -2.994 1.00 54.13 ? 91 GLN B OE1 1 ATOM 2020 N NE2 . GLN B 1 90 ? 26.520 47.449 -1.307 1.00 45.56 ? 91 GLN B NE2 1 ATOM 2021 N N . ILE B 1 91 ? 25.822 53.266 -1.297 1.00 42.56 ? 92 ILE B N 1 ATOM 2022 C CA . ILE B 1 91 ? 25.844 54.115 -2.480 1.00 42.07 ? 92 ILE B CA 1 ATOM 2023 C C . ILE B 1 91 ? 26.850 53.348 -3.352 1.00 45.69 ? 92 ILE B C 1 ATOM 2024 O O . ILE B 1 91 ? 28.023 53.247 -2.990 1.00 44.63 ? 92 ILE B O 1 ATOM 2025 C CB . ILE B 1 91 ? 26.234 55.589 -2.226 1.00 44.61 ? 92 ILE B CB 1 ATOM 2026 C CG1 . ILE B 1 91 ? 25.257 56.273 -1.282 1.00 43.35 ? 92 ILE B CG1 1 ATOM 2027 C CG2 . ILE B 1 91 ? 26.314 56.362 -3.547 1.00 45.24 ? 92 ILE B CG2 1 ATOM 2028 C CD1 . ILE B 1 91 ? 25.882 57.492 -0.626 1.00 42.09 ? 92 ILE B CD1 1 ATOM 2029 N N . SER B 1 92 ? 26.352 52.681 -4.402 1.00 43.32 ? 93 SER B N 1 ATOM 2030 C CA . SER B 1 92 ? 27.149 51.848 -5.300 1.00 43.42 ? 93 SER B CA 1 ATOM 2031 C C . SER B 1 92 ? 28.310 52.599 -5.954 1.00 49.51 ? 93 SER B C 1 ATOM 2032 O O . SER B 1 92 ? 29.419 52.062 -6.019 1.00 50.76 ? 93 SER B O 1 ATOM 2033 C CB . SER B 1 92 ? 26.267 51.160 -6.338 1.00 46.16 ? 93 SER B CB 1 ATOM 2034 O OG . SER B 1 92 ? 25.639 52.105 -7.185 1.00 54.47 ? 93 SER B OG 1 ATOM 2035 N N . ALA B 1 93 ? 28.063 53.828 -6.431 1.00 45.61 ? 94 ALA B N 1 ATOM 2036 C CA . ALA B 1 93 ? 29.098 54.678 -7.042 1.00 44.74 ? 94 ALA B CA 1 ATOM 2037 C C . ALA B 1 93 ? 28.730 56.103 -6.708 1.00 47.10 ? 94 ALA B C 1 ATOM 2038 O O . ALA B 1 93 ? 27.681 56.598 -7.142 1.00 47.85 ? 94 ALA B O 1 ATOM 2039 C CB . ALA B 1 93 ? 29.145 54.483 -8.555 1.00 44.81 ? 94 ALA B CB 1 ATOM 2040 N N . VAL B 1 94 ? 29.549 56.730 -5.872 1.00 40.20 ? 95 VAL B N 1 ATOM 2041 C CA . VAL B 1 94 ? 29.364 58.104 -5.419 1.00 39.19 ? 95 VAL B CA 1 ATOM 2042 C C . VAL B 1 94 ? 29.443 59.113 -6.592 1.00 44.10 ? 95 VAL B C 1 ATOM 2043 O O . VAL B 1 94 ? 30.229 58.916 -7.531 1.00 44.53 ? 95 VAL B O 1 ATOM 2044 C CB . VAL B 1 94 ? 30.337 58.387 -4.261 1.00 41.46 ? 95 VAL B CB 1 ATOM 2045 C CG1 . VAL B 1 94 ? 30.645 59.863 -4.105 1.00 40.99 ? 95 VAL B CG1 1 ATOM 2046 C CG2 . VAL B 1 94 ? 29.809 57.796 -2.965 1.00 41.21 ? 95 VAL B CG2 1 ATOM 2047 N N . ALA B 1 95 ? 28.559 60.146 -6.549 1.00 38.14 ? 96 ALA B N 1 ATOM 2048 C CA . ALA B 1 95 ? 28.466 61.235 -7.523 1.00 36.29 ? 96 ALA B CA 1 ATOM 2049 C C . ALA B 1 95 ? 28.176 62.499 -6.749 1.00 38.63 ? 96 ALA B C 1 ATOM 2050 O O . ALA B 1 95 ? 27.846 62.406 -5.574 1.00 38.17 ? 96 ALA B O 1 ATOM 2051 C CB . ALA B 1 95 ? 27.355 60.946 -8.529 1.00 37.02 ? 96 ALA B CB 1 ATOM 2052 N N . LEU B 1 96 ? 28.308 63.680 -7.363 1.00 37.76 ? 97 LEU B N 1 ATOM 2053 C CA . LEU B 1 96 ? 28.025 64.948 -6.655 1.00 38.88 ? 97 LEU B CA 1 ATOM 2054 C C . LEU B 1 96 ? 26.636 65.008 -6.002 1.00 44.31 ? 97 LEU B C 1 ATOM 2055 O O . LEU B 1 96 ? 26.503 65.569 -4.907 1.00 45.23 ? 97 LEU B O 1 ATOM 2056 C CB . LEU B 1 96 ? 28.223 66.173 -7.552 1.00 38.89 ? 97 LEU B CB 1 ATOM 2057 C CG . LEU B 1 96 ? 29.654 66.616 -7.788 1.00 43.01 ? 97 LEU B CG 1 ATOM 2058 C CD1 . LEU B 1 96 ? 29.691 67.801 -8.717 1.00 41.89 ? 97 LEU B CD1 1 ATOM 2059 C CD2 . LEU B 1 96 ? 30.343 67.034 -6.482 1.00 44.07 ? 97 LEU B CD2 1 ATOM 2060 N N . GLN B 1 97 ? 25.620 64.396 -6.645 1.00 40.65 ? 98 GLN B N 1 ATOM 2061 C CA . GLN B 1 97 ? 24.243 64.354 -6.129 1.00 40.57 ? 98 GLN B CA 1 ATOM 2062 C C . GLN B 1 97 ? 24.121 63.681 -4.746 1.00 41.94 ? 98 GLN B C 1 ATOM 2063 O O . GLN B 1 97 ? 23.131 63.913 -4.057 1.00 39.97 ? 98 GLN B O 1 ATOM 2064 C CB . GLN B 1 97 ? 23.291 63.694 -7.145 1.00 41.90 ? 98 GLN B CB 1 ATOM 2065 C CG . GLN B 1 97 ? 23.563 62.209 -7.409 1.00 58.93 ? 98 GLN B CG 1 ATOM 2066 C CD . GLN B 1 97 ? 22.317 61.452 -7.794 1.00 85.86 ? 98 GLN B CD 1 ATOM 2067 O OE1 . GLN B 1 97 ? 21.258 61.586 -7.165 1.00 83.33 ? 98 GLN B OE1 1 ATOM 2068 N NE2 . GLN B 1 97 ? 22.446 60.566 -8.773 1.00 82.85 ? 98 GLN B NE2 1 ATOM 2069 N N . HIS B 1 98 ? 25.130 62.867 -4.345 1.00 38.19 ? 99 HIS B N 1 ATOM 2070 C CA . HIS B 1 98 ? 25.150 62.141 -3.065 1.00 37.85 ? 99 HIS B CA 1 ATOM 2071 C C . HIS B 1 98 ? 25.535 62.955 -1.849 1.00 44.65 ? 99 HIS B C 1 ATOM 2072 O O . HIS B 1 98 ? 25.285 62.510 -0.736 1.00 44.90 ? 99 HIS B O 1 ATOM 2073 C CB . HIS B 1 98 ? 25.973 60.870 -3.155 1.00 37.23 ? 99 HIS B CB 1 ATOM 2074 C CG . HIS B 1 98 ? 25.390 59.890 -4.109 1.00 40.28 ? 99 HIS B CG 1 ATOM 2075 N ND1 . HIS B 1 98 ? 26.076 59.497 -5.238 1.00 42.22 ? 99 HIS B ND1 1 ATOM 2076 C CD2 . HIS B 1 98 ? 24.168 59.306 -4.112 1.00 42.33 ? 99 HIS B CD2 1 ATOM 2077 C CE1 . HIS B 1 98 ? 25.281 58.641 -5.867 1.00 41.86 ? 99 HIS B CE1 1 ATOM 2078 N NE2 . HIS B 1 98 ? 24.117 58.502 -5.233 1.00 42.26 ? 99 HIS B NE2 1 ATOM 2079 N N . GLU B 1 99 ? 26.125 64.148 -2.047 1.00 41.34 ? 100 GLU B N 1 ATOM 2080 C CA . GLU B 1 99 ? 26.506 65.034 -0.963 1.00 40.27 ? 100 GLU B CA 1 ATOM 2081 C C . GLU B 1 99 ? 25.265 65.493 -0.212 1.00 43.68 ? 100 GLU B C 1 ATOM 2082 O O . GLU B 1 99 ? 24.316 66.000 -0.811 1.00 42.71 ? 100 GLU B O 1 ATOM 2083 C CB . GLU B 1 99 ? 27.268 66.232 -1.521 1.00 41.53 ? 100 GLU B CB 1 ATOM 2084 C CG . GLU B 1 99 ? 27.694 67.235 -0.463 1.00 50.09 ? 100 GLU B CG 1 ATOM 2085 C CD . GLU B 1 99 ? 28.997 67.964 -0.728 1.00 67.99 ? 100 GLU B CD 1 ATOM 2086 O OE1 . GLU B 1 99 ? 29.963 67.329 -1.210 1.00 47.73 ? 100 GLU B OE1 1 ATOM 2087 O OE2 . GLU B 1 99 ? 29.081 69.157 -0.363 1.00 72.92 ? 100 GLU B OE2 1 ATOM 2088 N N . GLY B 1 100 ? 25.284 65.284 1.096 1.00 39.20 ? 101 GLY B N 1 ATOM 2089 C CA . GLY B 1 100 ? 24.201 65.666 1.983 1.00 37.37 ? 101 GLY B CA 1 ATOM 2090 C C . GLY B 1 100 ? 24.215 64.932 3.301 1.00 38.49 ? 101 GLY B C 1 ATOM 2091 O O . GLY B 1 100 ? 25.240 64.395 3.713 1.00 36.96 ? 101 GLY B O 1 ATOM 2092 N N . THR B 1 101 ? 23.062 64.924 3.973 1.00 34.76 ? 102 THR B N 1 ATOM 2093 C CA . THR B 1 101 ? 22.831 64.333 5.284 1.00 32.63 ? 102 THR B CA 1 ATOM 2094 C C . THR B 1 101 ? 22.092 63.042 5.141 1.00 35.93 ? 102 THR B C 1 ATOM 2095 O O . THR B 1 101 ? 21.098 62.984 4.426 1.00 38.10 ? 102 THR B O 1 ATOM 2096 C CB . THR B 1 101 ? 22.102 65.338 6.154 1.00 37.36 ? 102 THR B CB 1 ATOM 2097 O OG1 . THR B 1 101 ? 22.916 66.494 6.200 1.00 41.27 ? 102 THR B OG1 1 ATOM 2098 C CG2 . THR B 1 101 ? 21.900 64.856 7.576 1.00 38.35 ? 102 THR B CG2 1 ATOM 2099 N N . TYR B 1 102 ? 22.584 61.995 5.806 1.00 30.15 ? 103 TYR B N 1 ATOM 2100 C CA . TYR B 1 102 ? 21.975 60.680 5.783 1.00 29.05 ? 103 TYR B CA 1 ATOM 2101 C C . TYR B 1 102 ? 21.641 60.347 7.226 1.00 36.72 ? 103 TYR B C 1 ATOM 2102 O O . TYR B 1 102 ? 22.549 60.159 8.039 1.00 38.14 ? 103 TYR B O 1 ATOM 2103 C CB . TYR B 1 102 ? 22.935 59.658 5.154 1.00 28.85 ? 103 TYR B CB 1 ATOM 2104 C CG . TYR B 1 102 ? 23.183 59.860 3.675 1.00 29.48 ? 103 TYR B CG 1 ATOM 2105 C CD1 . TYR B 1 102 ? 23.915 60.957 3.207 1.00 29.78 ? 103 TYR B CD1 1 ATOM 2106 C CD2 . TYR B 1 102 ? 22.760 58.918 2.747 1.00 30.89 ? 103 TYR B CD2 1 ATOM 2107 C CE1 . TYR B 1 102 ? 24.107 61.171 1.845 1.00 29.18 ? 103 TYR B CE1 1 ATOM 2108 C CE2 . TYR B 1 102 ? 22.985 59.101 1.383 1.00 31.98 ? 103 TYR B CE2 1 ATOM 2109 C CZ . TYR B 1 102 ? 23.645 60.239 0.938 1.00 37.02 ? 103 TYR B CZ 1 ATOM 2110 O OH . TYR B 1 102 ? 23.865 60.420 -0.407 1.00 39.35 ? 103 TYR B OH 1 ATOM 2111 N N . THR B 1 103 ? 20.336 60.350 7.567 1.00 33.22 ? 104 THR B N 1 ATOM 2112 C CA . THR B 1 103 ? 19.851 60.094 8.921 1.00 32.15 ? 104 THR B CA 1 ATOM 2113 C C . THR B 1 103 ? 19.182 58.752 9.023 1.00 38.49 ? 104 THR B C 1 ATOM 2114 O O . THR B 1 103 ? 18.265 58.467 8.273 1.00 38.39 ? 104 THR B O 1 ATOM 2115 C CB . THR B 1 103 ? 18.963 61.229 9.388 1.00 33.96 ? 104 THR B CB 1 ATOM 2116 O OG1 . THR B 1 103 ? 19.676 62.459 9.258 1.00 32.48 ? 104 THR B OG1 1 ATOM 2117 C CG2 . THR B 1 103 ? 18.506 61.074 10.816 1.00 32.98 ? 104 THR B CG2 1 ATOM 2118 N N . CYS B 1 104 ? 19.649 57.915 9.940 1.00 37.91 ? 105 CYS B N 1 ATOM 2119 C CA . CYS B 1 104 ? 19.050 56.619 10.181 1.00 38.82 ? 105 CYS B CA 1 ATOM 2120 C C . CYS B 1 104 ? 18.207 56.740 11.438 1.00 41.78 ? 105 CYS B C 1 ATOM 2121 O O . CYS B 1 104 ? 18.725 57.041 12.515 1.00 41.42 ? 105 CYS B O 1 ATOM 2122 C CB . CYS B 1 104 ? 20.097 55.525 10.313 1.00 41.39 ? 105 CYS B CB 1 ATOM 2123 S SG . CYS B 1 104 ? 19.391 53.868 10.391 1.00 47.49 ? 105 CYS B SG 1 ATOM 2124 N N . GLU B 1 105 ? 16.890 56.607 11.276 1.00 37.42 ? 106 GLU B N 1 ATOM 2125 C CA . GLU B 1 105 ? 15.915 56.702 12.347 1.00 36.08 ? 106 GLU B CA 1 ATOM 2126 C C . GLU B 1 105 ? 15.524 55.303 12.688 1.00 36.27 ? 106 GLU B C 1 ATOM 2127 O O . GLU B 1 105 ? 15.105 54.548 11.819 1.00 34.54 ? 106 GLU B O 1 ATOM 2128 C CB . GLU B 1 105 ? 14.681 57.485 11.900 1.00 37.81 ? 106 GLU B CB 1 ATOM 2129 C CG . GLU B 1 105 ? 14.892 58.985 11.806 1.00 51.06 ? 106 GLU B CG 1 ATOM 2130 C CD . GLU B 1 105 ? 13.634 59.806 11.583 1.00 78.06 ? 106 GLU B CD 1 ATOM 2131 O OE1 . GLU B 1 105 ? 12.568 59.229 11.258 1.00 70.69 ? 106 GLU B OE1 1 ATOM 2132 O OE2 . GLU B 1 105 ? 13.736 61.050 11.678 1.00 80.15 ? 106 GLU B OE2 1 ATOM 2133 N N . ILE B 1 106 ? 15.726 54.933 13.940 1.00 34.39 ? 107 ILE B N 1 ATOM 2134 C CA . ILE B 1 106 ? 15.402 53.596 14.418 1.00 34.54 ? 107 ILE B CA 1 ATOM 2135 C C . ILE B 1 106 ? 14.241 53.688 15.399 1.00 39.73 ? 107 ILE B C 1 ATOM 2136 O O . ILE B 1 106 ? 14.283 54.481 16.344 1.00 38.72 ? 107 ILE B O 1 ATOM 2137 C CB . ILE B 1 106 ? 16.635 52.858 15.037 1.00 36.65 ? 107 ILE B CB 1 ATOM 2138 C CG1 . ILE B 1 106 ? 17.875 52.850 14.081 1.00 34.90 ? 107 ILE B CG1 1 ATOM 2139 C CG2 . ILE B 1 106 ? 16.271 51.442 15.497 1.00 37.47 ? 107 ILE B CG2 1 ATOM 2140 C CD1 . ILE B 1 106 ? 19.064 53.603 14.688 1.00 34.30 ? 107 ILE B CD1 1 ATOM 2141 N N . VAL B 1 107 ? 13.205 52.875 15.157 1.00 38.05 ? 108 VAL B N 1 ATOM 2142 C CA . VAL B 1 107 ? 12.053 52.779 16.053 1.00 39.18 ? 108 VAL B CA 1 ATOM 2143 C C . VAL B 1 107 ? 12.160 51.412 16.740 1.00 43.71 ? 108 VAL B C 1 ATOM 2144 O O . VAL B 1 107 ? 12.247 50.362 16.078 1.00 43.30 ? 108 VAL B O 1 ATOM 2145 C CB . VAL B 1 107 ? 10.675 52.993 15.338 1.00 43.64 ? 108 VAL B CB 1 ATOM 2146 C CG1 . VAL B 1 107 ? 9.510 52.579 16.226 1.00 42.79 ? 108 VAL B CG1 1 ATOM 2147 C CG2 . VAL B 1 107 ? 10.506 54.447 14.890 1.00 43.71 ? 108 VAL B CG2 1 ATOM 2148 N N . THR B 1 108 ? 12.189 51.444 18.060 1.00 40.10 ? 109 THR B N 1 ATOM 2149 C CA . THR B 1 108 ? 12.259 50.244 18.891 1.00 41.45 ? 109 THR B CA 1 ATOM 2150 C C . THR B 1 108 ? 11.025 50.285 19.833 1.00 49.78 ? 109 THR B C 1 ATOM 2151 O O . THR B 1 108 ? 10.428 51.366 20.003 1.00 49.11 ? 109 THR B O 1 ATOM 2152 C CB . THR B 1 108 ? 13.572 50.261 19.761 1.00 44.45 ? 109 THR B CB 1 ATOM 2153 O OG1 . THR B 1 108 ? 13.496 51.319 20.740 1.00 36.78 ? 109 THR B OG1 1 ATOM 2154 C CG2 . THR B 1 108 ? 14.860 50.383 18.931 1.00 41.46 ? 109 THR B CG2 1 ATOM 2155 N N . PRO B 1 109 ? 10.693 49.184 20.553 1.00 47.90 ? 110 PRO B N 1 ATOM 2156 C CA . PRO B 1 109 ? 9.579 49.256 21.521 1.00 48.20 ? 110 PRO B CA 1 ATOM 2157 C C . PRO B 1 109 ? 9.764 50.292 22.641 1.00 54.92 ? 110 PRO B C 1 ATOM 2158 O O . PRO B 1 109 ? 8.771 50.766 23.181 1.00 56.95 ? 110 PRO B O 1 ATOM 2159 C CB . PRO B 1 109 ? 9.516 47.843 22.081 1.00 50.11 ? 110 PRO B CB 1 ATOM 2160 C CG . PRO B 1 109 ? 10.146 46.979 21.006 1.00 54.48 ? 110 PRO B CG 1 ATOM 2161 C CD . PRO B 1 109 ? 11.262 47.822 20.499 1.00 49.81 ? 110 PRO B CD 1 ATOM 2162 N N . GLU B 1 110 ? 11.014 50.687 22.956 1.00 50.40 ? 111 GLU B N 1 ATOM 2163 C CA . GLU B 1 110 ? 11.324 51.660 24.018 1.00 49.62 ? 111 GLU B CA 1 ATOM 2164 C C . GLU B 1 110 ? 11.303 53.108 23.546 1.00 51.71 ? 111 GLU B C 1 ATOM 2165 O O . GLU B 1 110 ? 11.129 54.025 24.354 1.00 52.82 ? 111 GLU B O 1 ATOM 2166 C CB . GLU B 1 110 ? 12.698 51.365 24.651 1.00 50.92 ? 111 GLU B CB 1 ATOM 2167 C CG . GLU B 1 110 ? 12.752 50.096 25.480 1.00 62.57 ? 111 GLU B CG 1 ATOM 2168 C CD . GLU B 1 110 ? 12.653 48.794 24.707 1.00 87.07 ? 111 GLU B CD 1 ATOM 2169 O OE1 . GLU B 1 110 ? 13.368 48.637 23.689 1.00 67.23 ? 111 GLU B OE1 1 ATOM 2170 O OE2 . GLU B 1 110 ? 11.835 47.936 25.111 1.00 91.66 ? 111 GLU B OE2 1 ATOM 2171 N N . GLY B 1 111 ? 11.562 53.321 22.269 1.00 45.21 ? 112 GLY B N 1 ATOM 2172 C CA . GLY B 1 111 ? 11.602 54.674 21.749 1.00 44.41 ? 112 GLY B CA 1 ATOM 2173 C C . GLY B 1 111 ? 12.382 54.826 20.467 1.00 48.27 ? 112 GLY B C 1 ATOM 2174 O O . GLY B 1 111 ? 12.569 53.863 19.701 1.00 46.94 ? 112 GLY B O 1 ATOM 2175 N N . ASN B 1 112 ? 12.852 56.062 20.248 1.00 44.76 ? 113 ASN B N 1 ATOM 2176 C CA . ASN B 1 112 ? 13.586 56.376 19.035 1.00 45.36 ? 113 ASN B CA 1 ATOM 2177 C C . ASN B 1 112 ? 15.068 56.607 19.231 1.00 45.60 ? 113 ASN B C 1 ATOM 2178 O O . ASN B 1 112 ? 15.497 57.348 20.132 1.00 44.65 ? 113 ASN B O 1 ATOM 2179 C CB . ASN B 1 112 ? 12.965 57.579 18.312 1.00 52.23 ? 113 ASN B CB 1 ATOM 2180 C CG . ASN B 1 112 ? 11.463 57.496 18.110 1.00 67.11 ? 113 ASN B CG 1 ATOM 2181 O OD1 . ASN B 1 112 ? 10.922 56.478 17.685 1.00 53.08 ? 113 ASN B OD1 1 ATOM 2182 N ND2 . ASN B 1 112 ? 10.758 58.573 18.421 1.00 56.08 ? 113 ASN B ND2 1 ATOM 2183 N N . LEU B 1 113 ? 15.830 56.015 18.314 1.00 38.76 ? 114 LEU B N 1 ATOM 2184 C CA . LEU B 1 113 ? 17.278 56.139 18.218 1.00 37.08 ? 114 LEU B CA 1 ATOM 2185 C C . LEU B 1 113 ? 17.634 56.721 16.850 1.00 39.85 ? 114 LEU B C 1 ATOM 2186 O O . LEU B 1 113 ? 16.841 56.613 15.919 1.00 38.77 ? 114 LEU B O 1 ATOM 2187 C CB . LEU B 1 113 ? 17.960 54.755 18.405 1.00 36.26 ? 114 LEU B CB 1 ATOM 2188 C CG . LEU B 1 113 ? 17.478 53.871 19.565 1.00 37.20 ? 114 LEU B CG 1 ATOM 2189 C CD1 . LEU B 1 113 ? 18.069 52.508 19.450 1.00 36.72 ? 114 LEU B CD1 1 ATOM 2190 C CD2 . LEU B 1 113 ? 17.769 54.507 20.923 1.00 33.32 ? 114 LEU B CD2 1 ATOM 2191 N N . GLU B 1 114 ? 18.810 57.354 16.731 1.00 37.18 ? 115 GLU B N 1 ATOM 2192 C CA . GLU B 1 114 ? 19.287 57.886 15.452 1.00 36.79 ? 115 GLU B CA 1 ATOM 2193 C C . GLU B 1 114 ? 20.788 57.911 15.269 1.00 39.22 ? 115 GLU B C 1 ATOM 2194 O O . GLU B 1 114 ? 21.531 58.119 16.223 1.00 38.09 ? 115 GLU B O 1 ATOM 2195 C CB . GLU B 1 114 ? 18.658 59.231 15.051 1.00 37.80 ? 115 GLU B CB 1 ATOM 2196 C CG . GLU B 1 114 ? 19.189 60.431 15.799 1.00 51.23 ? 115 GLU B CG 1 ATOM 2197 C CD . GLU B 1 114 ? 18.824 61.788 15.231 1.00 74.91 ? 115 GLU B CD 1 ATOM 2198 O OE1 . GLU B 1 114 ? 17.859 61.874 14.438 1.00 76.22 ? 115 GLU B OE1 1 ATOM 2199 O OE2 . GLU B 1 114 ? 19.489 62.778 15.612 1.00 68.88 ? 115 GLU B OE2 1 ATOM 2200 N N . LYS B 1 115 ? 21.205 57.712 14.015 1.00 34.07 ? 116 LYS B N 1 ATOM 2201 C CA . LYS B 1 115 ? 22.573 57.821 13.543 1.00 33.29 ? 116 LYS B CA 1 ATOM 2202 C C . LYS B 1 115 ? 22.570 58.846 12.383 1.00 37.31 ? 116 LYS B C 1 ATOM 2203 O O . LYS B 1 115 ? 21.806 58.692 11.440 1.00 36.19 ? 116 LYS B O 1 ATOM 2204 C CB . LYS B 1 115 ? 23.095 56.445 13.073 1.00 33.94 ? 116 LYS B CB 1 ATOM 2205 C CG . LYS B 1 115 ? 24.586 56.409 12.768 1.00 37.53 ? 116 LYS B CG 1 ATOM 2206 C CD . LYS B 1 115 ? 25.442 56.586 14.008 1.00 41.44 ? 116 LYS B CD 1 ATOM 2207 C CE . LYS B 1 115 ? 26.900 56.268 13.790 1.00 42.25 ? 116 LYS B CE 1 ATOM 2208 N NZ . LYS B 1 115 ? 27.743 56.812 14.900 1.00 42.98 ? 116 LYS B NZ 1 ATOM 2209 N N . VAL B 1 116 ? 23.407 59.889 12.466 1.00 34.01 ? 117 VAL B N 1 ATOM 2210 C CA . VAL B 1 116 ? 23.506 60.920 11.436 1.00 32.71 ? 117 VAL B CA 1 ATOM 2211 C C . VAL B 1 116 ? 24.900 60.909 10.772 1.00 36.96 ? 117 VAL B C 1 ATOM 2212 O O . VAL B 1 116 ? 25.911 60.934 11.465 1.00 35.43 ? 117 VAL B O 1 ATOM 2213 C CB . VAL B 1 116 ? 23.156 62.332 11.996 1.00 35.05 ? 117 VAL B CB 1 ATOM 2214 C CG1 . VAL B 1 116 ? 23.143 63.380 10.886 1.00 33.89 ? 117 VAL B CG1 1 ATOM 2215 C CG2 . VAL B 1 116 ? 21.833 62.333 12.761 1.00 34.54 ? 117 VAL B CG2 1 ATOM 2216 N N . TYR B 1 117 ? 24.935 60.884 9.429 1.00 35.22 ? 118 TYR B N 1 ATOM 2217 C CA . TYR B 1 117 ? 26.137 61.006 8.603 1.00 35.15 ? 118 TYR B CA 1 ATOM 2218 C C . TYR B 1 117 ? 26.049 62.263 7.748 1.00 40.78 ? 118 TYR B C 1 ATOM 2219 O O . TYR B 1 117 ? 25.017 62.542 7.156 1.00 41.13 ? 118 TYR B O 1 ATOM 2220 C CB . TYR B 1 117 ? 26.310 59.818 7.670 1.00 36.19 ? 118 TYR B CB 1 ATOM 2221 C CG . TYR B 1 117 ? 26.660 58.534 8.385 1.00 38.04 ? 118 TYR B CG 1 ATOM 2222 C CD1 . TYR B 1 117 ? 27.987 58.203 8.656 1.00 39.28 ? 118 TYR B CD1 1 ATOM 2223 C CD2 . TYR B 1 117 ? 25.668 57.629 8.765 1.00 38.21 ? 118 TYR B CD2 1 ATOM 2224 C CE1 . TYR B 1 117 ? 28.316 57.025 9.326 1.00 38.79 ? 118 TYR B CE1 1 ATOM 2225 C CE2 . TYR B 1 117 ? 25.984 56.443 9.434 1.00 39.03 ? 118 TYR B CE2 1 ATOM 2226 C CZ . TYR B 1 117 ? 27.312 56.139 9.707 1.00 49.42 ? 118 TYR B CZ 1 ATOM 2227 O OH . TYR B 1 117 ? 27.638 54.954 10.341 1.00 52.90 ? 118 TYR B OH 1 ATOM 2228 N N . ASP B 1 118 ? 27.142 62.987 7.657 1.00 38.19 ? 119 ASP B N 1 ATOM 2229 C CA . ASP B 1 118 ? 27.285 64.170 6.828 1.00 38.82 ? 119 ASP B CA 1 ATOM 2230 C C . ASP B 1 118 ? 28.288 63.742 5.755 1.00 42.11 ? 119 ASP B C 1 ATOM 2231 O O . ASP B 1 118 ? 29.469 63.599 6.031 1.00 42.83 ? 119 ASP B O 1 ATOM 2232 C CB . ASP B 1 118 ? 27.839 65.304 7.696 1.00 42.23 ? 119 ASP B CB 1 ATOM 2233 C CG . ASP B 1 118 ? 27.775 66.693 7.119 1.00 64.00 ? 119 ASP B CG 1 ATOM 2234 O OD1 . ASP B 1 118 ? 28.137 66.862 5.933 1.00 66.93 ? 119 ASP B OD1 1 ATOM 2235 O OD2 . ASP B 1 118 ? 27.485 67.637 7.887 1.00 73.42 ? 119 ASP B OD2 1 ATOM 2236 N N . LEU B 1 119 ? 27.799 63.428 4.570 1.00 39.03 ? 120 LEU B N 1 ATOM 2237 C CA . LEU B 1 119 ? 28.601 62.937 3.463 1.00 38.90 ? 120 LEU B CA 1 ATOM 2238 C C . LEU B 1 119 ? 29.094 64.070 2.535 1.00 44.19 ? 120 LEU B C 1 ATOM 2239 O O . LEU B 1 119 ? 28.296 64.852 2.015 1.00 42.47 ? 120 LEU B O 1 ATOM 2240 C CB . LEU B 1 119 ? 27.788 61.888 2.712 1.00 39.39 ? 120 LEU B CB 1 ATOM 2241 C CG . LEU B 1 119 ? 28.543 60.953 1.768 1.00 44.81 ? 120 LEU B CG 1 ATOM 2242 C CD1 . LEU B 1 119 ? 27.904 59.583 1.780 1.00 45.25 ? 120 LEU B CD1 1 ATOM 2243 C CD2 . LEU B 1 119 ? 28.456 61.454 0.366 1.00 46.35 ? 120 LEU B CD2 1 ATOM 2244 N N . GLN B 1 120 ? 30.433 64.180 2.372 1.00 41.86 ? 121 GLN B N 1 ATOM 2245 C CA . GLN B 1 120 ? 31.101 65.161 1.509 1.00 40.87 ? 121 GLN B CA 1 ATOM 2246 C C . GLN B 1 120 ? 31.688 64.417 0.336 1.00 42.48 ? 121 GLN B C 1 ATOM 2247 O O . GLN B 1 120 ? 32.282 63.359 0.523 1.00 42.18 ? 121 GLN B O 1 ATOM 2248 C CB . GLN B 1 120 ? 32.222 65.886 2.252 1.00 43.10 ? 121 GLN B CB 1 ATOM 2249 C CG . GLN B 1 120 ? 31.775 66.778 3.418 1.00 77.88 ? 121 GLN B CG 1 ATOM 2250 C CD . GLN B 1 120 ? 31.219 68.091 2.917 1.00 111.87 ? 121 GLN B CD 1 ATOM 2251 O OE1 . GLN B 1 120 ? 31.933 68.904 2.314 1.00 110.61 ? 121 GLN B OE1 1 ATOM 2252 N NE2 . GLN B 1 120 ? 29.923 68.310 3.125 1.00 103.77 ? 121 GLN B NE2 1 ATOM 2253 N N . VAL B 1 121 ? 31.502 64.941 -0.873 1.00 38.06 ? 122 VAL B N 1 ATOM 2254 C CA . VAL B 1 121 ? 32.025 64.322 -2.085 1.00 37.75 ? 122 VAL B CA 1 ATOM 2255 C C . VAL B 1 121 ? 33.278 65.069 -2.540 1.00 41.58 ? 122 VAL B C 1 ATOM 2256 O O . VAL B 1 121 ? 33.301 66.304 -2.609 1.00 39.67 ? 122 VAL B O 1 ATOM 2257 C CB . VAL B 1 121 ? 30.956 64.161 -3.212 1.00 41.62 ? 122 VAL B CB 1 ATOM 2258 C CG1 . VAL B 1 121 ? 31.556 63.535 -4.468 1.00 40.74 ? 122 VAL B CG1 1 ATOM 2259 C CG2 . VAL B 1 121 ? 29.772 63.318 -2.727 1.00 41.98 ? 122 VAL B CG2 1 ATOM 2260 N N . LEU B 1 122 ? 34.335 64.299 -2.802 1.00 38.76 ? 123 LEU B N 1 ATOM 2261 C CA . LEU B 1 122 ? 35.621 64.803 -3.287 1.00 37.16 ? 123 LEU B CA 1 ATOM 2262 C C . LEU B 1 122 ? 35.748 64.491 -4.745 1.00 38.12 ? 123 LEU B C 1 ATOM 2263 O O . LEU B 1 122 ? 35.506 63.360 -5.141 1.00 37.82 ? 123 LEU B O 1 ATOM 2264 C CB . LEU B 1 122 ? 36.799 64.186 -2.501 1.00 36.81 ? 123 LEU B CB 1 ATOM 2265 C CG . LEU B 1 122 ? 36.771 64.310 -0.949 1.00 39.39 ? 123 LEU B CG 1 ATOM 2266 C CD1 . LEU B 1 122 ? 37.931 63.620 -0.349 1.00 39.26 ? 123 LEU B CD1 1 ATOM 2267 C CD2 . LEU B 1 122 ? 36.765 65.752 -0.489 1.00 39.15 ? 123 LEU B CD2 1 ATOM 2268 N N . VAL B 1 123 ? 36.081 65.507 -5.547 1.00 35.33 ? 124 VAL B N 1 ATOM 2269 C CA . VAL B 1 123 ? 36.253 65.395 -6.996 1.00 34.87 ? 124 VAL B CA 1 ATOM 2270 C C . VAL B 1 123 ? 37.719 65.656 -7.370 1.00 37.19 ? 124 VAL B C 1 ATOM 2271 O O . VAL B 1 123 ? 38.205 66.770 -7.195 1.00 35.56 ? 124 VAL B O 1 ATOM 2272 C CB . VAL B 1 123 ? 35.312 66.350 -7.781 1.00 37.91 ? 124 VAL B CB 1 ATOM 2273 C CG1 . VAL B 1 123 ? 35.416 66.107 -9.279 1.00 36.86 ? 124 VAL B CG1 1 ATOM 2274 C CG2 . VAL B 1 123 ? 33.867 66.215 -7.314 1.00 37.59 ? 124 VAL B CG2 1 ATOM 2275 N N . PRO B 1 124 ? 38.439 64.650 -7.890 1.00 35.81 ? 125 PRO B N 1 ATOM 2276 C CA . PRO B 1 124 ? 39.830 64.890 -8.334 1.00 35.26 ? 125 PRO B CA 1 ATOM 2277 C C . PRO B 1 124 ? 39.902 65.859 -9.519 1.00 36.33 ? 125 PRO B C 1 ATOM 2278 O O . PRO B 1 124 ? 39.114 65.700 -10.453 1.00 36.60 ? 125 PRO B O 1 ATOM 2279 C CB . PRO B 1 124 ? 40.296 63.502 -8.783 1.00 37.23 ? 125 PRO B CB 1 ATOM 2280 C CG . PRO B 1 124 ? 39.339 62.526 -8.178 1.00 42.82 ? 125 PRO B CG 1 ATOM 2281 C CD . PRO B 1 124 ? 38.031 63.245 -8.127 1.00 38.40 ? 125 PRO B CD 1 ATOM 2282 N N . PRO B 1 125 ? 40.810 66.868 -9.539 1.00 30.34 ? 126 PRO B N 1 ATOM 2283 C CA . PRO B 1 125 ? 40.868 67.757 -10.707 1.00 29.67 ? 126 PRO B CA 1 ATOM 2284 C C . PRO B 1 125 ? 41.455 67.072 -11.948 1.00 36.89 ? 126 PRO B C 1 ATOM 2285 O O . PRO B 1 125 ? 42.224 66.118 -11.815 1.00 37.26 ? 126 PRO B O 1 ATOM 2286 C CB . PRO B 1 125 ? 41.741 68.914 -10.230 1.00 30.56 ? 126 PRO B CB 1 ATOM 2287 C CG . PRO B 1 125 ? 42.622 68.321 -9.200 1.00 34.73 ? 126 PRO B CG 1 ATOM 2288 C CD . PRO B 1 125 ? 41.839 67.223 -8.539 1.00 30.80 ? 126 PRO B CD 1 ATOM 2289 N N . GLU B 1 126 ? 41.048 67.519 -13.156 1.00 33.94 ? 127 GLU B N 1 ATOM 2290 C CA . GLU B 1 126 ? 41.599 67.018 -14.416 1.00 33.01 ? 127 GLU B CA 1 ATOM 2291 C C . GLU B 1 126 ? 42.679 68.010 -14.792 1.00 35.53 ? 127 GLU B C 1 ATOM 2292 O O . GLU B 1 126 ? 42.410 69.201 -14.899 1.00 34.40 ? 127 GLU B O 1 ATOM 2293 C CB . GLU B 1 126 ? 40.538 66.949 -15.498 1.00 34.64 ? 127 GLU B CB 1 ATOM 2294 C CG . GLU B 1 126 ? 39.632 65.740 -15.373 1.00 51.38 ? 127 GLU B CG 1 ATOM 2295 C CD . GLU B 1 126 ? 38.687 65.514 -16.535 1.00 83.01 ? 127 GLU B CD 1 ATOM 2296 O OE1 . GLU B 1 126 ? 38.424 66.470 -17.303 1.00 81.23 ? 127 GLU B OE1 1 ATOM 2297 O OE2 . GLU B 1 126 ? 38.175 64.376 -16.649 1.00 85.30 ? 127 GLU B OE2 1 ATOM 2298 N N . VAL B 1 127 ? 43.921 67.550 -14.892 1.00 32.78 ? 128 VAL B N 1 ATOM 2299 C CA . VAL B 1 127 ? 45.039 68.454 -15.124 1.00 32.80 ? 128 VAL B CA 1 ATOM 2300 C C . VAL B 1 127 ? 45.516 68.542 -16.558 1.00 34.96 ? 128 VAL B C 1 ATOM 2301 O O . VAL B 1 127 ? 45.336 67.626 -17.353 1.00 34.65 ? 128 VAL B O 1 ATOM 2302 C CB . VAL B 1 127 ? 46.216 68.243 -14.129 1.00 37.93 ? 128 VAL B CB 1 ATOM 2303 C CG1 . VAL B 1 127 ? 45.725 68.287 -12.676 1.00 37.48 ? 128 VAL B CG1 1 ATOM 2304 C CG2 . VAL B 1 127 ? 46.949 66.939 -14.416 1.00 38.44 ? 128 VAL B CG2 1 ATOM 2305 N N . THR B 1 128 ? 46.163 69.643 -16.858 1.00 29.97 ? 129 THR B N 1 ATOM 2306 C CA . THR B 1 128 ? 46.799 69.896 -18.122 1.00 30.22 ? 129 THR B CA 1 ATOM 2307 C C . THR B 1 128 ? 47.980 70.813 -17.906 1.00 32.63 ? 129 THR B C 1 ATOM 2308 O O . THR B 1 128 ? 47.984 71.615 -16.965 1.00 32.68 ? 129 THR B O 1 ATOM 2309 C CB . THR B 1 128 ? 45.822 70.303 -19.238 1.00 47.31 ? 129 THR B CB 1 ATOM 2310 O OG1 . THR B 1 128 ? 46.518 70.113 -20.475 1.00 61.59 ? 129 THR B OG1 1 ATOM 2311 C CG2 . THR B 1 128 ? 45.330 71.753 -19.111 1.00 39.08 ? 129 THR B CG2 1 ATOM 2312 N N . TYR B 1 129 ? 49.011 70.631 -18.733 1.00 27.92 ? 130 TYR B N 1 ATOM 2313 C CA . TYR B 1 129 ? 50.257 71.370 -18.670 1.00 28.00 ? 130 TYR B CA 1 ATOM 2314 C C . TYR B 1 129 ? 50.695 71.696 -20.073 1.00 34.78 ? 130 TYR B C 1 ATOM 2315 O O . TYR B 1 129 ? 50.561 70.861 -20.952 1.00 35.50 ? 130 TYR B O 1 ATOM 2316 C CB . TYR B 1 129 ? 51.370 70.522 -18.036 1.00 28.45 ? 130 TYR B CB 1 ATOM 2317 C CG . TYR B 1 129 ? 51.015 69.735 -16.799 1.00 27.96 ? 130 TYR B CG 1 ATOM 2318 C CD1 . TYR B 1 129 ? 50.410 68.481 -16.894 1.00 28.39 ? 130 TYR B CD1 1 ATOM 2319 C CD2 . TYR B 1 129 ? 51.329 70.213 -15.537 1.00 28.30 ? 130 TYR B CD2 1 ATOM 2320 C CE1 . TYR B 1 129 ? 50.123 67.732 -15.761 1.00 28.67 ? 130 TYR B CE1 1 ATOM 2321 C CE2 . TYR B 1 129 ? 51.058 69.469 -14.395 1.00 28.02 ? 130 TYR B CE2 1 ATOM 2322 C CZ . TYR B 1 129 ? 50.455 68.228 -14.513 1.00 36.01 ? 130 TYR B CZ 1 ATOM 2323 O OH . TYR B 1 129 ? 50.190 67.495 -13.386 1.00 35.14 ? 130 TYR B OH 1 ATOM 2324 N N . PHE B 1 130 ? 51.233 72.887 -20.294 1.00 34.01 ? 131 PHE B N 1 ATOM 2325 C CA . PHE B 1 130 ? 51.752 73.215 -21.609 1.00 35.28 ? 131 PHE B CA 1 ATOM 2326 C C . PHE B 1 130 ? 52.655 74.392 -21.634 1.00 40.35 ? 131 PHE B C 1 ATOM 2327 O O . PHE B 1 130 ? 52.401 75.330 -20.894 1.00 39.00 ? 131 PHE B O 1 ATOM 2328 C CB . PHE B 1 130 ? 50.653 73.366 -22.668 1.00 37.67 ? 131 PHE B CB 1 ATOM 2329 C CG . PHE B 1 130 ? 49.503 74.291 -22.369 1.00 38.97 ? 131 PHE B CG 1 ATOM 2330 C CD1 . PHE B 1 130 ? 48.366 73.826 -21.703 1.00 39.56 ? 131 PHE B CD1 1 ATOM 2331 C CD2 . PHE B 1 130 ? 49.505 75.598 -22.846 1.00 41.91 ? 131 PHE B CD2 1 ATOM 2332 C CE1 . PHE B 1 130 ? 47.290 74.670 -21.452 1.00 42.24 ? 131 PHE B CE1 1 ATOM 2333 C CE2 . PHE B 1 130 ? 48.406 76.437 -22.633 1.00 42.08 ? 131 PHE B CE2 1 ATOM 2334 C CZ . PHE B 1 130 ? 47.303 75.963 -21.944 1.00 41.29 ? 131 PHE B CZ 1 ATOM 2335 N N . PRO B 1 131 ? 53.722 74.386 -22.476 1.00 40.29 ? 132 PRO B N 1 ATOM 2336 C CA . PRO B 1 131 ? 54.524 75.620 -22.618 1.00 40.41 ? 132 PRO B CA 1 ATOM 2337 C C . PRO B 1 131 ? 53.748 76.609 -23.483 1.00 45.94 ? 132 PRO B C 1 ATOM 2338 O O . PRO B 1 131 ? 52.901 76.224 -24.289 1.00 44.93 ? 132 PRO B O 1 ATOM 2339 C CB . PRO B 1 131 ? 55.810 75.163 -23.314 1.00 42.18 ? 132 PRO B CB 1 ATOM 2340 C CG . PRO B 1 131 ? 55.546 73.765 -23.814 1.00 46.44 ? 132 PRO B CG 1 ATOM 2341 C CD . PRO B 1 131 ? 54.158 73.335 -23.426 1.00 42.04 ? 132 PRO B CD 1 ATOM 2342 N N . GLY B 1 132 ? 54.007 77.877 -23.270 1.00 45.92 ? 133 GLY B N 1 ATOM 2343 C CA . GLY B 1 132 ? 53.397 78.947 -24.048 1.00 46.41 ? 133 GLY B CA 1 ATOM 2344 C C . GLY B 1 132 ? 54.473 79.717 -24.785 1.00 52.37 ? 133 GLY B C 1 ATOM 2345 O O . GLY B 1 132 ? 55.654 79.333 -24.754 1.00 52.27 ? 133 GLY B O 1 ATOM 2346 N N . LYS B 1 133 ? 54.080 80.824 -25.429 1.00 51.17 ? 134 LYS B N 1 ATOM 2347 C CA . LYS B 1 133 ? 55.049 81.642 -26.153 1.00 52.50 ? 134 LYS B CA 1 ATOM 2348 C C . LYS B 1 133 ? 55.854 82.499 -25.202 1.00 56.05 ? 134 LYS B C 1 ATOM 2349 O O . LYS B 1 133 ? 55.354 82.899 -24.154 1.00 57.06 ? 134 LYS B O 1 ATOM 2350 C CB . LYS B 1 133 ? 54.364 82.482 -27.256 1.00 57.04 ? 134 LYS B CB 1 ATOM 2351 C CG . LYS B 1 133 ? 53.839 81.608 -28.405 1.00 83.25 ? 134 LYS B CG 1 ATOM 2352 C CD . LYS B 1 133 ? 53.546 82.378 -29.681 1.00 99.46 ? 134 LYS B CD 1 ATOM 2353 C CE . LYS B 1 133 ? 53.266 81.418 -30.822 1.00 113.50 ? 134 LYS B CE 1 ATOM 2354 N NZ . LYS B 1 133 ? 52.246 81.940 -31.773 1.00 122.64 ? 134 LYS B NZ 1 ATOM 2355 N N . ASN B 1 134 ? 57.109 82.741 -25.544 1.00 51.95 ? 135 ASN B N 1 ATOM 2356 C CA . ASN B 1 134 ? 58.026 83.610 -24.809 1.00 52.28 ? 135 ASN B CA 1 ATOM 2357 C C . ASN B 1 134 ? 58.280 83.209 -23.366 1.00 53.86 ? 135 ASN B C 1 ATOM 2358 O O . ASN B 1 134 ? 58.064 84.003 -22.437 1.00 53.83 ? 135 ASN B O 1 ATOM 2359 C CB . ASN B 1 134 ? 57.681 85.124 -24.982 1.00 58.50 ? 135 ASN B CB 1 ATOM 2360 C CG . ASN B 1 134 ? 58.771 86.114 -24.558 1.00 97.92 ? 135 ASN B CG 1 ATOM 2361 O OD1 . ASN B 1 134 ? 59.961 85.775 -24.415 1.00 86.22 ? 135 ASN B OD1 1 ATOM 2362 N ND2 . ASN B 1 134 ? 58.377 87.374 -24.339 1.00 97.13 ? 135 ASN B ND2 1 ATOM 2363 N N . ARG B 1 135 ? 58.782 81.979 -23.193 1.00 47.19 ? 136 ARG B N 1 ATOM 2364 C CA . ARG B 1 135 ? 59.183 81.441 -21.897 1.00 45.09 ? 136 ARG B CA 1 ATOM 2365 C C . ARG B 1 135 ? 58.079 81.454 -20.808 1.00 44.39 ? 136 ARG B C 1 ATOM 2366 O O . ARG B 1 135 ? 58.328 81.829 -19.658 1.00 42.68 ? 136 ARG B O 1 ATOM 2367 C CB . ARG B 1 135 ? 60.466 82.137 -21.438 1.00 45.17 ? 136 ARG B CB 1 ATOM 2368 C CG . ARG B 1 135 ? 61.665 81.783 -22.310 1.00 52.56 ? 136 ARG B CG 1 ATOM 2369 C CD . ARG B 1 135 ? 62.904 82.539 -21.872 1.00 65.28 ? 136 ARG B CD 1 ATOM 2370 N NE . ARG B 1 135 ? 63.251 82.335 -20.461 1.00 67.65 ? 136 ARG B NE 1 ATOM 2371 C CZ . ARG B 1 135 ? 63.822 81.237 -19.977 1.00 77.40 ? 136 ARG B CZ 1 ATOM 2372 N NH1 . ARG B 1 135 ? 64.087 80.207 -20.777 1.00 62.10 ? 136 ARG B NH1 1 ATOM 2373 N NH2 . ARG B 1 135 ? 64.114 81.150 -18.689 1.00 61.56 ? 136 ARG B NH2 1 ATOM 2374 N N . THR B 1 136 ? 56.852 81.096 -21.215 1.00 37.59 ? 137 THR B N 1 ATOM 2375 C CA . THR B 1 136 ? 55.717 80.981 -20.328 1.00 36.10 ? 137 THR B CA 1 ATOM 2376 C C . THR B 1 136 ? 55.290 79.512 -20.237 1.00 39.26 ? 137 THR B C 1 ATOM 2377 O O . THR B 1 136 ? 55.612 78.703 -21.108 1.00 39.55 ? 137 THR B O 1 ATOM 2378 C CB . THR B 1 136 ? 54.536 81.900 -20.753 1.00 45.50 ? 137 THR B CB 1 ATOM 2379 O OG1 . THR B 1 136 ? 53.964 81.451 -21.981 1.00 46.00 ? 137 THR B OG1 1 ATOM 2380 C CG2 . THR B 1 136 ? 54.904 83.382 -20.813 1.00 39.39 ? 137 THR B CG2 1 ATOM 2381 N N . ALA B 1 137 ? 54.601 79.161 -19.168 1.00 34.52 ? 138 ALA B N 1 ATOM 2382 C CA . ALA B 1 137 ? 54.091 77.813 -18.990 1.00 33.61 ? 138 ALA B CA 1 ATOM 2383 C C . ALA B 1 137 ? 52.708 77.957 -18.352 1.00 35.86 ? 138 ALA B C 1 ATOM 2384 O O . ALA B 1 137 ? 52.456 78.921 -17.615 1.00 33.37 ? 138 ALA B O 1 ATOM 2385 C CB . ALA B 1 137 ? 55.036 76.973 -18.112 1.00 33.63 ? 138 ALA B CB 1 ATOM 2386 N N . VAL B 1 138 ? 51.810 77.022 -18.686 1.00 31.26 ? 139 VAL B N 1 ATOM 2387 C CA . VAL B 1 138 ? 50.459 76.985 -18.173 1.00 31.04 ? 139 VAL B CA 1 ATOM 2388 C C . VAL B 1 138 ? 50.203 75.662 -17.470 1.00 36.10 ? 139 VAL B C 1 ATOM 2389 O O . VAL B 1 138 ? 50.605 74.605 -17.954 1.00 36.07 ? 139 VAL B O 1 ATOM 2390 C CB . VAL B 1 138 ? 49.408 77.285 -19.286 1.00 34.58 ? 139 VAL B CB 1 ATOM 2391 C CG1 . VAL B 1 138 ? 47.964 77.283 -18.745 1.00 33.18 ? 139 VAL B CG1 1 ATOM 2392 C CG2 . VAL B 1 138 ? 49.725 78.605 -20.000 1.00 33.71 ? 139 VAL B CG2 1 ATOM 2393 N N . CYS B 1 139 ? 49.534 75.735 -16.319 1.00 33.36 ? 140 CYS B N 1 ATOM 2394 C CA . CYS B 1 139 ? 49.123 74.593 -15.519 1.00 32.67 ? 140 CYS B CA 1 ATOM 2395 C C . CYS B 1 139 ? 47.674 74.815 -15.118 1.00 35.68 ? 140 CYS B C 1 ATOM 2396 O O . CYS B 1 139 ? 47.353 75.864 -14.579 1.00 34.92 ? 140 CYS B O 1 ATOM 2397 C CB . CYS B 1 139 ? 50.009 74.462 -14.293 1.00 33.15 ? 140 CYS B CB 1 ATOM 2398 S SG . CYS B 1 139 ? 49.902 72.854 -13.494 1.00 37.66 ? 140 CYS B SG 1 ATOM 2399 N N . GLU B 1 140 ? 46.800 73.863 -15.405 1.00 32.30 ? 141 GLU B N 1 ATOM 2400 C CA . GLU B 1 140 ? 45.384 73.958 -15.090 1.00 32.41 ? 141 GLU B CA 1 ATOM 2401 C C . GLU B 1 140 ? 44.911 72.733 -14.359 1.00 35.15 ? 141 GLU B C 1 ATOM 2402 O O . GLU B 1 140 ? 45.319 71.627 -14.685 1.00 35.95 ? 141 GLU B O 1 ATOM 2403 C CB . GLU B 1 140 ? 44.537 74.163 -16.363 1.00 34.83 ? 141 GLU B CB 1 ATOM 2404 C CG . GLU B 1 140 ? 44.972 75.350 -17.233 1.00 49.11 ? 141 GLU B CG 1 ATOM 2405 C CD . GLU B 1 140 ? 44.275 75.562 -18.568 1.00 73.29 ? 141 GLU B CD 1 ATOM 2406 O OE1 . GLU B 1 140 ? 43.600 74.631 -19.061 1.00 78.55 ? 141 GLU B OE1 1 ATOM 2407 O OE2 . GLU B 1 140 ? 44.451 76.654 -19.152 1.00 67.24 ? 141 GLU B OE2 1 ATOM 2408 N N . ALA B 1 141 ? 44.012 72.931 -13.397 1.00 31.58 ? 142 ALA B N 1 ATOM 2409 C CA . ALA B 1 141 ? 43.391 71.887 -12.586 1.00 32.08 ? 142 ALA B CA 1 ATOM 2410 C C . ALA B 1 141 ? 41.895 72.138 -12.699 1.00 36.18 ? 142 ALA B C 1 ATOM 2411 O O . ALA B 1 141 ? 41.343 72.974 -11.991 1.00 36.24 ? 142 ALA B O 1 ATOM 2412 C CB . ALA B 1 141 ? 43.852 71.996 -11.125 1.00 32.38 ? 142 ALA B CB 1 ATOM 2413 N N . MET B 1 142 ? 41.261 71.431 -13.612 1.00 33.41 ? 143 MET B N 1 ATOM 2414 C CA . MET B 1 142 ? 39.859 71.555 -13.985 1.00 35.25 ? 143 MET B CA 1 ATOM 2415 C C . MET B 1 142 ? 38.882 70.843 -13.085 1.00 39.12 ? 143 MET B C 1 ATOM 2416 O O . MET B 1 142 ? 38.956 69.623 -12.939 1.00 38.99 ? 143 MET B O 1 ATOM 2417 C CB . MET B 1 142 ? 39.643 71.059 -15.432 1.00 39.05 ? 143 MET B CB 1 ATOM 2418 C CG . MET B 1 142 ? 39.336 72.149 -16.428 1.00 45.18 ? 143 MET B CG 1 ATOM 2419 S SD . MET B 1 142 ? 40.711 73.286 -16.673 1.00 52.64 ? 143 MET B SD 1 ATOM 2420 C CE . MET B 1 142 ? 41.510 72.486 -18.017 1.00 50.40 ? 143 MET B CE 1 ATOM 2421 N N . ALA B 1 143 ? 37.897 71.612 -12.564 1.00 34.41 ? 144 ALA B N 1 ATOM 2422 C CA . ALA B 1 143 ? 36.735 71.165 -11.816 1.00 32.94 ? 144 ALA B CA 1 ATOM 2423 C C . ALA B 1 143 ? 37.031 70.180 -10.687 1.00 36.32 ? 144 ALA B C 1 ATOM 2424 O O . ALA B 1 143 ? 36.541 69.051 -10.673 1.00 35.92 ? 144 ALA B O 1 ATOM 2425 C CB . ALA B 1 143 ? 35.662 70.612 -12.772 1.00 33.24 ? 144 ALA B CB 1 ATOM 2426 N N . GLY B 1 144 ? 37.789 70.651 -9.722 1.00 32.70 ? 145 GLY B N 1 ATOM 2427 C CA . GLY B 1 144 ? 38.120 69.852 -8.563 1.00 33.29 ? 145 GLY B CA 1 ATOM 2428 C C . GLY B 1 144 ? 37.299 70.244 -7.362 1.00 40.17 ? 145 GLY B C 1 ATOM 2429 O O . GLY B 1 144 ? 36.862 71.398 -7.257 1.00 40.98 ? 145 GLY B O 1 ATOM 2430 N N . LYS B 1 145 ? 37.111 69.303 -6.419 1.00 35.87 ? 146 LYS B N 1 ATOM 2431 C CA . LYS B 1 145 ? 36.379 69.600 -5.188 1.00 34.47 ? 146 LYS B CA 1 ATOM 2432 C C . LYS B 1 145 ? 37.093 68.928 -4.020 1.00 34.67 ? 146 LYS B C 1 ATOM 2433 O O . LYS B 1 145 ? 37.108 67.698 -3.947 1.00 34.14 ? 146 LYS B O 1 ATOM 2434 C CB . LYS B 1 145 ? 34.896 69.182 -5.279 1.00 36.54 ? 146 LYS B CB 1 ATOM 2435 C CG . LYS B 1 145 ? 34.041 69.732 -4.152 1.00 31.98 ? 146 LYS B CG 1 ATOM 2436 C CD . LYS B 1 145 ? 32.615 69.200 -4.198 1.00 30.53 ? 146 LYS B CD 1 ATOM 2437 C CE . LYS B 1 145 ? 31.845 69.547 -2.941 1.00 43.07 ? 146 LYS B CE 1 ATOM 2438 N NZ . LYS B 1 145 ? 32.303 68.764 -1.761 1.00 48.37 ? 146 LYS B NZ 1 ATOM 2439 N N . PRO B 1 146 ? 37.712 69.693 -3.111 1.00 30.33 ? 147 PRO B N 1 ATOM 2440 C CA . PRO B 1 146 ? 37.838 71.164 -3.090 1.00 29.97 ? 147 PRO B CA 1 ATOM 2441 C C . PRO B 1 146 ? 38.768 71.676 -4.190 1.00 37.16 ? 147 PRO B C 1 ATOM 2442 O O . PRO B 1 146 ? 39.286 70.894 -4.970 1.00 37.99 ? 147 PRO B O 1 ATOM 2443 C CB . PRO B 1 146 ? 38.367 71.453 -1.679 1.00 30.53 ? 147 PRO B CB 1 ATOM 2444 C CG . PRO B 1 146 ? 39.040 70.228 -1.235 1.00 35.74 ? 147 PRO B CG 1 ATOM 2445 C CD . PRO B 1 146 ? 38.386 69.071 -1.951 1.00 32.48 ? 147 PRO B CD 1 ATOM 2446 N N . ALA B 1 147 ? 38.957 72.983 -4.284 1.00 35.49 ? 148 ALA B N 1 ATOM 2447 C CA . ALA B 1 147 ? 39.869 73.549 -5.268 1.00 34.78 ? 148 ALA B CA 1 ATOM 2448 C C . ALA B 1 147 ? 41.275 72.977 -5.052 1.00 39.66 ? 148 ALA B C 1 ATOM 2449 O O . ALA B 1 147 ? 41.743 72.879 -3.922 1.00 39.89 ? 148 ALA B O 1 ATOM 2450 C CB . ALA B 1 147 ? 39.925 75.059 -5.106 1.00 35.45 ? 148 ALA B CB 1 ATOM 2451 N N . ALA B 1 148 ? 41.954 72.630 -6.134 1.00 36.37 ? 149 ALA B N 1 ATOM 2452 C CA . ALA B 1 148 ? 43.330 72.174 -6.085 1.00 34.32 ? 149 ALA B CA 1 ATOM 2453 C C . ALA B 1 148 ? 44.213 73.385 -5.835 1.00 36.46 ? 149 ALA B C 1 ATOM 2454 O O . ALA B 1 148 ? 43.763 74.518 -5.992 1.00 35.78 ? 149 ALA B O 1 ATOM 2455 C CB . ALA B 1 148 ? 43.698 71.539 -7.410 1.00 34.50 ? 149 ALA B CB 1 ATOM 2456 N N . GLN B 1 149 ? 45.453 73.167 -5.407 1.00 33.15 ? 150 GLN B N 1 ATOM 2457 C CA . GLN B 1 149 ? 46.402 74.266 -5.266 1.00 31.93 ? 150 GLN B CA 1 ATOM 2458 C C . GLN B 1 149 ? 47.536 74.023 -6.248 1.00 33.89 ? 150 GLN B C 1 ATOM 2459 O O . GLN B 1 149 ? 48.068 72.902 -6.344 1.00 32.85 ? 150 GLN B O 1 ATOM 2460 C CB . GLN B 1 149 ? 46.944 74.392 -3.852 1.00 33.58 ? 150 GLN B CB 1 ATOM 2461 C CG . GLN B 1 149 ? 45.935 74.886 -2.837 1.00 52.65 ? 150 GLN B CG 1 ATOM 2462 C CD . GLN B 1 149 ? 46.601 74.948 -1.495 1.00 72.73 ? 150 GLN B CD 1 ATOM 2463 O OE1 . GLN B 1 149 ? 46.981 73.922 -0.921 1.00 65.58 ? 150 GLN B OE1 1 ATOM 2464 N NE2 . GLN B 1 149 ? 46.811 76.162 -0.991 1.00 69.32 ? 150 GLN B NE2 1 ATOM 2465 N N . ILE B 1 150 ? 47.902 75.081 -6.966 1.00 29.96 ? 151 ILE B N 1 ATOM 2466 C CA . ILE B 1 150 ? 48.966 75.052 -7.951 1.00 29.39 ? 151 ILE B CA 1 ATOM 2467 C C . ILE B 1 150 ? 50.217 75.740 -7.446 1.00 34.25 ? 151 ILE B C 1 ATOM 2468 O O . ILE B 1 150 ? 50.162 76.883 -7.019 1.00 33.71 ? 151 ILE B O 1 ATOM 2469 C CB . ILE B 1 150 ? 48.492 75.583 -9.331 1.00 31.36 ? 151 ILE B CB 1 ATOM 2470 C CG1 . ILE B 1 150 ? 47.452 74.615 -9.947 1.00 31.38 ? 151 ILE B CG1 1 ATOM 2471 C CG2 . ILE B 1 150 ? 49.695 75.817 -10.260 1.00 30.79 ? 151 ILE B CG2 1 ATOM 2472 C CD1 . ILE B 1 150 ? 46.811 75.043 -11.251 1.00 38.88 ? 151 ILE B CD1 1 ATOM 2473 N N . SER B 1 151 ? 51.350 75.035 -7.486 1.00 32.48 ? 152 SER B N 1 ATOM 2474 C CA . SER B 1 151 ? 52.632 75.629 -7.124 1.00 31.18 ? 152 SER B CA 1 ATOM 2475 C C . SER B 1 151 ? 53.684 75.298 -8.177 1.00 36.07 ? 152 SER B C 1 ATOM 2476 O O . SER B 1 151 ? 53.646 74.221 -8.799 1.00 36.09 ? 152 SER B O 1 ATOM 2477 C CB . SER B 1 151 ? 53.053 75.231 -5.721 1.00 30.37 ? 152 SER B CB 1 ATOM 2478 O OG . SER B 1 151 ? 53.170 73.831 -5.612 1.00 37.45 ? 152 SER B OG 1 ATOM 2479 N N . TRP B 1 152 ? 54.565 76.273 -8.436 1.00 31.82 ? 153 TRP B N 1 ATOM 2480 C CA . TRP B 1 152 ? 55.625 76.161 -9.439 1.00 30.99 ? 153 TRP B CA 1 ATOM 2481 C C . TRP B 1 152 ? 57.029 76.095 -8.854 1.00 37.90 ? 153 TRP B C 1 ATOM 2482 O O . TRP B 1 152 ? 57.324 76.761 -7.854 1.00 37.57 ? 153 TRP B O 1 ATOM 2483 C CB . TRP B 1 152 ? 55.577 77.349 -10.380 1.00 28.31 ? 153 TRP B CB 1 ATOM 2484 C CG . TRP B 1 152 ? 54.354 77.422 -11.226 1.00 28.36 ? 153 TRP B CG 1 ATOM 2485 C CD1 . TRP B 1 152 ? 53.217 78.126 -10.963 1.00 30.91 ? 153 TRP B CD1 1 ATOM 2486 C CD2 . TRP B 1 152 ? 54.188 76.860 -12.538 1.00 27.68 ? 153 TRP B CD2 1 ATOM 2487 N NE1 . TRP B 1 152 ? 52.329 77.995 -12.005 1.00 30.28 ? 153 TRP B NE1 1 ATOM 2488 C CE2 . TRP B 1 152 ? 52.913 77.250 -13.000 1.00 31.05 ? 153 TRP B CE2 1 ATOM 2489 C CE3 . TRP B 1 152 ? 54.983 76.030 -13.352 1.00 28.46 ? 153 TRP B CE3 1 ATOM 2490 C CZ2 . TRP B 1 152 ? 52.434 76.889 -14.262 1.00 29.85 ? 153 TRP B CZ2 1 ATOM 2491 C CZ3 . TRP B 1 152 ? 54.494 75.648 -14.590 1.00 29.30 ? 153 TRP B CZ3 1 ATOM 2492 C CH2 . TRP B 1 152 ? 53.230 76.068 -15.030 1.00 29.75 ? 153 TRP B CH2 1 ATOM 2493 N N . THR B 1 153 ? 57.911 75.337 -9.541 1.00 37.37 ? 154 THR B N 1 ATOM 2494 C CA . THR B 1 153 ? 59.347 75.244 -9.241 1.00 37.78 ? 154 THR B CA 1 ATOM 2495 C C . THR B 1 153 ? 60.128 75.486 -10.537 1.00 42.82 ? 154 THR B C 1 ATOM 2496 O O . THR B 1 153 ? 59.891 74.763 -11.502 1.00 43.52 ? 154 THR B O 1 ATOM 2497 C CB . THR B 1 153 ? 59.723 73.920 -8.608 1.00 41.76 ? 154 THR B CB 1 ATOM 2498 O OG1 . THR B 1 153 ? 58.876 73.700 -7.491 1.00 42.46 ? 154 THR B OG1 1 ATOM 2499 C CG2 . THR B 1 153 ? 61.134 73.924 -8.108 1.00 39.69 ? 154 THR B CG2 1 ATOM 2500 N N . PRO B 1 154 ? 61.066 76.465 -10.600 1.00 39.08 ? 155 PRO B N 1 ATOM 2501 C CA . PRO B 1 154 ? 61.417 77.461 -9.575 1.00 38.69 ? 155 PRO B CA 1 ATOM 2502 C C . PRO B 1 154 ? 60.354 78.576 -9.516 1.00 45.55 ? 155 PRO B C 1 ATOM 2503 O O . PRO B 1 154 ? 59.361 78.522 -10.248 1.00 44.92 ? 155 PRO B O 1 ATOM 2504 C CB . PRO B 1 154 ? 62.778 77.965 -10.065 1.00 39.39 ? 155 PRO B CB 1 ATOM 2505 C CG . PRO B 1 154 ? 62.655 77.940 -11.563 1.00 43.44 ? 155 PRO B CG 1 ATOM 2506 C CD . PRO B 1 154 ? 61.814 76.714 -11.855 1.00 39.91 ? 155 PRO B CD 1 ATOM 2507 N N . ASP B 1 155 ? 60.574 79.595 -8.673 1.00 44.32 ? 156 ASP B N 1 ATOM 2508 C CA . ASP B 1 155 ? 59.652 80.721 -8.531 1.00 44.77 ? 156 ASP B CA 1 ATOM 2509 C C . ASP B 1 155 ? 59.619 81.545 -9.792 1.00 49.12 ? 156 ASP B C 1 ATOM 2510 O O . ASP B 1 155 ? 60.671 81.951 -10.309 1.00 49.60 ? 156 ASP B O 1 ATOM 2511 C CB . ASP B 1 155 ? 60.083 81.656 -7.372 1.00 47.18 ? 156 ASP B CB 1 ATOM 2512 C CG . ASP B 1 155 ? 60.149 81.049 -5.979 1.00 53.78 ? 156 ASP B CG 1 ATOM 2513 O OD1 . ASP B 1 155 ? 59.274 80.190 -5.660 1.00 52.92 ? 156 ASP B OD1 1 ATOM 2514 O OD2 . ASP B 1 155 ? 61.053 81.470 -5.187 1.00 54.94 ? 156 ASP B OD2 1 ATOM 2515 N N . GLY B 1 156 ? 58.415 81.837 -10.245 1.00 45.19 ? 157 GLY B N 1 ATOM 2516 C CA . GLY B 1 156 ? 58.222 82.677 -11.417 1.00 45.05 ? 157 GLY B CA 1 ATOM 2517 C C . GLY B 1 156 ? 57.271 83.801 -11.120 1.00 48.42 ? 157 GLY B C 1 ATOM 2518 O O . GLY B 1 156 ? 56.795 83.933 -9.992 1.00 48.31 ? 157 GLY B O 1 ATOM 2519 N N . ASP B 1 157 ? 56.976 84.595 -12.136 1.00 44.08 ? 158 ASP B N 1 ATOM 2520 C CA . ASP B 1 157 ? 55.990 85.647 -12.041 1.00 43.14 ? 158 ASP B CA 1 ATOM 2521 C C . ASP B 1 157 ? 54.690 85.060 -12.613 1.00 46.32 ? 158 ASP B C 1 ATOM 2522 O O . ASP B 1 157 ? 54.586 84.870 -13.829 1.00 46.80 ? 158 ASP B O 1 ATOM 2523 C CB . ASP B 1 157 ? 56.472 86.903 -12.772 1.00 44.46 ? 158 ASP B CB 1 ATOM 2524 C CG . ASP B 1 157 ? 57.824 87.376 -12.286 1.00 55.02 ? 158 ASP B CG 1 ATOM 2525 O OD1 . ASP B 1 157 ? 58.008 87.502 -11.060 1.00 52.65 ? 158 ASP B OD1 1 ATOM 2526 O OD2 . ASP B 1 157 ? 58.718 87.543 -13.123 1.00 74.03 ? 158 ASP B OD2 1 ATOM 2527 N N . CYS B 1 158 ? 53.769 84.640 -11.719 1.00 42.88 ? 159 CYS B N 1 ATOM 2528 C CA . CYS B 1 158 ? 52.526 84.009 -12.168 1.00 44.64 ? 159 CYS B CA 1 ATOM 2529 C C . CYS B 1 158 ? 51.253 84.800 -11.937 1.00 42.20 ? 159 CYS B C 1 ATOM 2530 O O . CYS B 1 158 ? 51.213 85.780 -11.176 1.00 41.83 ? 159 CYS B O 1 ATOM 2531 C CB . CYS B 1 158 ? 52.360 82.576 -11.661 1.00 48.23 ? 159 CYS B CB 1 ATOM 2532 S SG . CYS B 1 158 ? 53.890 81.693 -11.273 1.00 54.38 ? 159 CYS B SG 1 ATOM 2533 N N . VAL B 1 159 ? 50.203 84.332 -12.610 1.00 33.26 ? 160 VAL B N 1 ATOM 2534 C CA . VAL B 1 159 ? 48.845 84.804 -12.494 1.00 33.06 ? 160 VAL B CA 1 ATOM 2535 C C . VAL B 1 159 ? 47.995 83.551 -12.366 1.00 37.39 ? 160 VAL B C 1 ATOM 2536 O O . VAL B 1 159 ? 47.969 82.730 -13.287 1.00 37.38 ? 160 VAL B O 1 ATOM 2537 C CB . VAL B 1 159 ? 48.375 85.756 -13.631 1.00 36.79 ? 160 VAL B CB 1 ATOM 2538 C CG1 . VAL B 1 159 ? 46.903 86.143 -13.446 1.00 36.02 ? 160 VAL B CG1 1 ATOM 2539 C CG2 . VAL B 1 159 ? 49.250 87.007 -13.690 1.00 36.72 ? 160 VAL B CG2 1 ATOM 2540 N N . THR B 1 160 ? 47.368 83.362 -11.198 1.00 34.13 ? 161 THR B N 1 ATOM 2541 C CA . THR B 1 160 ? 46.520 82.188 -10.955 1.00 34.59 ? 161 THR B CA 1 ATOM 2542 C C . THR B 1 160 ? 45.074 82.593 -10.813 1.00 36.31 ? 161 THR B C 1 ATOM 2543 O O . THR B 1 160 ? 44.746 83.405 -9.957 1.00 37.55 ? 161 THR B O 1 ATOM 2544 C CB . THR B 1 160 ? 47.063 81.330 -9.805 1.00 37.63 ? 161 THR B CB 1 ATOM 2545 O OG1 . THR B 1 160 ? 48.425 81.026 -10.096 1.00 35.37 ? 161 THR B OG1 1 ATOM 2546 C CG2 . THR B 1 160 ? 46.292 80.044 -9.636 1.00 30.83 ? 161 THR B CG2 1 ATOM 2547 N N . LYS B 1 161 ? 44.224 82.057 -11.664 1.00 30.34 ? 162 LYS B N 1 ATOM 2548 C CA . LYS B 1 161 ? 42.812 82.390 -11.671 1.00 30.20 ? 162 LYS B CA 1 ATOM 2549 C C . LYS B 1 161 ? 41.959 81.203 -11.267 1.00 36.44 ? 162 LYS B C 1 ATOM 2550 O O . LYS B 1 161 ? 42.139 80.106 -11.803 1.00 38.58 ? 162 LYS B O 1 ATOM 2551 C CB . LYS B 1 161 ? 42.387 82.933 -13.057 1.00 32.08 ? 162 LYS B CB 1 ATOM 2552 C CG . LYS B 1 161 ? 43.042 84.236 -13.418 1.00 40.75 ? 162 LYS B CG 1 ATOM 2553 C CD . LYS B 1 161 ? 42.497 84.815 -14.698 1.00 52.57 ? 162 LYS B CD 1 ATOM 2554 C CE . LYS B 1 161 ? 43.270 86.057 -15.073 1.00 67.78 ? 162 LYS B CE 1 ATOM 2555 N NZ . LYS B 1 161 ? 42.658 86.773 -16.218 1.00 82.91 ? 162 LYS B NZ 1 ATOM 2556 N N . SER B 1 162 ? 41.018 81.411 -10.343 1.00 33.30 ? 163 SER B N 1 ATOM 2557 C CA . SER B 1 162 ? 40.121 80.346 -9.923 1.00 35.13 ? 163 SER B CA 1 ATOM 2558 C C . SER B 1 162 ? 38.678 80.693 -10.293 1.00 44.20 ? 163 SER B C 1 ATOM 2559 O O . SER B 1 162 ? 38.281 81.853 -10.188 1.00 46.31 ? 163 SER B O 1 ATOM 2560 C CB . SER B 1 162 ? 40.284 80.057 -8.432 1.00 42.01 ? 163 SER B CB 1 ATOM 2561 O OG . SER B 1 162 ? 39.556 80.988 -7.641 1.00 59.57 ? 163 SER B OG 1 ATOM 2562 N N . GLU B 1 163 ? 37.922 79.709 -10.775 1.00 41.22 ? 164 GLU B N 1 ATOM 2563 C CA . GLU B 1 163 ? 36.538 79.886 -11.187 1.00 41.74 ? 164 GLU B CA 1 ATOM 2564 C C . GLU B 1 163 ? 35.666 78.873 -10.455 1.00 48.76 ? 164 GLU B C 1 ATOM 2565 O O . GLU B 1 163 ? 35.854 77.669 -10.597 1.00 47.36 ? 164 GLU B O 1 ATOM 2566 C CB . GLU B 1 163 ? 36.430 79.731 -12.715 1.00 43.41 ? 164 GLU B CB 1 ATOM 2567 C CG . GLU B 1 163 ? 35.046 80.005 -13.284 1.00 59.29 ? 164 GLU B CG 1 ATOM 2568 C CD . GLU B 1 163 ? 34.750 79.508 -14.694 1.00 86.73 ? 164 GLU B CD 1 ATOM 2569 O OE1 . GLU B 1 163 ? 35.699 79.097 -15.399 1.00 79.68 ? 164 GLU B OE1 1 ATOM 2570 O OE2 . GLU B 1 163 ? 33.562 79.525 -15.092 1.00 81.99 ? 164 GLU B OE2 1 ATOM 2571 N N . SER B 1 164 ? 34.751 79.363 -9.620 1.00 48.41 ? 165 SER B N 1 ATOM 2572 C CA . SER B 1 164 ? 33.819 78.516 -8.880 1.00 48.55 ? 165 SER B CA 1 ATOM 2573 C C . SER B 1 164 ? 32.671 78.137 -9.792 1.00 53.92 ? 165 SER B C 1 ATOM 2574 O O . SER B 1 164 ? 32.173 78.997 -10.508 1.00 56.29 ? 165 SER B O 1 ATOM 2575 C CB . SER B 1 164 ? 33.293 79.236 -7.643 1.00 53.32 ? 165 SER B CB 1 ATOM 2576 O OG . SER B 1 164 ? 32.676 80.471 -7.966 1.00 67.34 ? 165 SER B OG 1 ATOM 2577 N N . HIS B 1 165 ? 32.287 76.854 -9.809 1.00 49.30 ? 166 HIS B N 1 ATOM 2578 C CA . HIS B 1 165 ? 31.184 76.333 -10.610 1.00 48.69 ? 166 HIS B CA 1 ATOM 2579 C C . HIS B 1 165 ? 29.995 76.033 -9.713 1.00 52.66 ? 166 HIS B C 1 ATOM 2580 O O . HIS B 1 165 ? 30.180 75.727 -8.532 1.00 50.81 ? 166 HIS B O 1 ATOM 2581 C CB . HIS B 1 165 ? 31.597 75.068 -11.364 1.00 49.41 ? 166 HIS B CB 1 ATOM 2582 C CG . HIS B 1 165 ? 32.856 75.226 -12.161 1.00 53.01 ? 166 HIS B CG 1 ATOM 2583 N ND1 . HIS B 1 165 ? 32.952 76.123 -13.213 1.00 55.02 ? 166 HIS B ND1 1 ATOM 2584 C CD2 . HIS B 1 165 ? 34.033 74.577 -12.043 1.00 54.65 ? 166 HIS B CD2 1 ATOM 2585 C CE1 . HIS B 1 165 ? 34.182 75.994 -13.686 1.00 53.91 ? 166 HIS B CE1 1 ATOM 2586 N NE2 . HIS B 1 165 ? 34.865 75.075 -13.019 1.00 54.00 ? 166 HIS B NE2 1 ATOM 2587 N N . SER B 1 166 ? 28.773 76.095 -10.283 1.00 50.91 ? 167 SER B N 1 ATOM 2588 C CA . SER B 1 166 ? 27.527 75.866 -9.529 1.00 50.67 ? 167 SER B CA 1 ATOM 2589 C C . SER B 1 166 ? 27.406 74.468 -8.876 1.00 53.20 ? 167 SER B C 1 ATOM 2590 O O . SER B 1 166 ? 26.766 74.342 -7.822 1.00 52.80 ? 167 SER B O 1 ATOM 2591 C CB . SER B 1 166 ? 26.293 76.249 -10.347 1.00 53.46 ? 167 SER B CB 1 ATOM 2592 O OG . SER B 1 166 ? 26.034 75.366 -11.424 1.00 62.65 ? 167 SER B OG 1 ATOM 2593 N N . ASN B 1 167 ? 28.093 73.449 -9.448 1.00 47.86 ? 168 ASN B N 1 ATOM 2594 C CA . ASN B 1 167 ? 28.133 72.081 -8.890 1.00 46.50 ? 168 ASN B CA 1 ATOM 2595 C C . ASN B 1 167 ? 29.025 71.929 -7.641 1.00 50.13 ? 168 ASN B C 1 ATOM 2596 O O . ASN B 1 167 ? 29.021 70.859 -7.023 1.00 49.66 ? 168 ASN B O 1 ATOM 2597 C CB . ASN B 1 167 ? 28.492 71.034 -9.941 1.00 40.91 ? 168 ASN B CB 1 ATOM 2598 C CG . ASN B 1 167 ? 29.832 71.207 -10.630 1.00 54.84 ? 168 ASN B CG 1 ATOM 2599 O OD1 . ASN B 1 167 ? 30.714 71.956 -10.182 1.00 56.54 ? 168 ASN B OD1 1 ATOM 2600 N ND2 . ASN B 1 167 ? 29.977 70.494 -11.744 1.00 45.28 ? 168 ASN B ND2 1 ATOM 2601 N N . GLY B 1 168 ? 29.762 72.984 -7.275 1.00 44.71 ? 169 GLY B N 1 ATOM 2602 C CA . GLY B 1 168 ? 30.615 72.950 -6.091 1.00 43.31 ? 169 GLY B CA 1 ATOM 2603 C C . GLY B 1 168 ? 32.094 72.710 -6.373 1.00 46.30 ? 169 GLY B C 1 ATOM 2604 O O . GLY B 1 168 ? 32.911 72.697 -5.440 1.00 46.68 ? 169 GLY B O 1 ATOM 2605 N N . THR B 1 169 ? 32.447 72.508 -7.665 1.00 38.83 ? 170 THR B N 1 ATOM 2606 C CA . THR B 1 169 ? 33.817 72.316 -8.077 1.00 37.60 ? 170 THR B CA 1 ATOM 2607 C C . THR B 1 169 ? 34.461 73.670 -8.389 1.00 44.13 ? 170 THR B C 1 ATOM 2608 O O . THR B 1 169 ? 33.759 74.684 -8.473 1.00 44.24 ? 170 THR B O 1 ATOM 2609 C CB . THR B 1 169 ? 33.923 71.308 -9.215 1.00 37.24 ? 170 THR B CB 1 ATOM 2610 O OG1 . THR B 1 169 ? 33.453 71.889 -10.435 1.00 39.07 ? 170 THR B OG1 1 ATOM 2611 C CG2 . THR B 1 169 ? 33.238 69.957 -8.906 1.00 26.75 ? 170 THR B CG2 1 ATOM 2612 N N . VAL B 1 170 ? 35.808 73.700 -8.499 1.00 39.66 ? 171 VAL B N 1 ATOM 2613 C CA . VAL B 1 170 ? 36.577 74.904 -8.798 1.00 37.43 ? 171 VAL B CA 1 ATOM 2614 C C . VAL B 1 170 ? 37.622 74.561 -9.841 1.00 39.05 ? 171 VAL B C 1 ATOM 2615 O O . VAL B 1 170 ? 38.340 73.576 -9.691 1.00 39.08 ? 171 VAL B O 1 ATOM 2616 C CB . VAL B 1 170 ? 37.238 75.521 -7.516 1.00 39.69 ? 171 VAL B CB 1 ATOM 2617 C CG1 . VAL B 1 170 ? 38.015 76.804 -7.833 1.00 38.60 ? 171 VAL B CG1 1 ATOM 2618 C CG2 . VAL B 1 170 ? 36.232 75.755 -6.384 1.00 38.12 ? 171 VAL B CG2 1 ATOM 2619 N N . THR B 1 171 ? 37.714 75.380 -10.889 1.00 34.80 ? 172 THR B N 1 ATOM 2620 C CA . THR B 1 171 ? 38.750 75.288 -11.902 1.00 33.09 ? 172 THR B CA 1 ATOM 2621 C C . THR B 1 171 ? 39.823 76.316 -11.538 1.00 35.87 ? 172 THR B C 1 ATOM 2622 O O . THR B 1 171 ? 39.510 77.486 -11.370 1.00 36.90 ? 172 THR B O 1 ATOM 2623 C CB . THR B 1 171 ? 38.185 75.512 -13.294 1.00 37.77 ? 172 THR B CB 1 ATOM 2624 O OG1 . THR B 1 171 ? 37.408 74.368 -13.647 1.00 43.00 ? 172 THR B OG1 1 ATOM 2625 C CG2 . THR B 1 171 ? 39.283 75.732 -14.346 1.00 30.28 ? 172 THR B CG2 1 ATOM 2626 N N . VAL B 1 172 ? 41.081 75.879 -11.413 1.00 29.93 ? 173 VAL B N 1 ATOM 2627 C CA . VAL B 1 172 ? 42.227 76.748 -11.128 1.00 27.69 ? 173 VAL B CA 1 ATOM 2628 C C . VAL B 1 172 ? 43.159 76.705 -12.379 1.00 33.14 ? 173 VAL B C 1 ATOM 2629 O O . VAL B 1 172 ? 43.453 75.620 -12.878 1.00 32.19 ? 173 VAL B O 1 ATOM 2630 C CB . VAL B 1 172 ? 42.960 76.350 -9.827 1.00 28.74 ? 173 VAL B CB 1 ATOM 2631 C CG1 . VAL B 1 172 ? 43.994 77.392 -9.459 1.00 28.16 ? 173 VAL B CG1 1 ATOM 2632 C CG2 . VAL B 1 172 ? 41.982 76.172 -8.677 1.00 27.93 ? 173 VAL B CG2 1 ATOM 2633 N N . ARG B 1 173 ? 43.554 77.889 -12.910 1.00 30.23 ? 174 ARG B N 1 ATOM 2634 C CA . ARG B 1 173 ? 44.413 78.048 -14.093 1.00 29.71 ? 174 ARG B CA 1 ATOM 2635 C C . ARG B 1 173 ? 45.557 78.940 -13.754 1.00 32.90 ? 174 ARG B C 1 ATOM 2636 O O . ARG B 1 173 ? 45.338 80.080 -13.371 1.00 36.58 ? 174 ARG B O 1 ATOM 2637 C CB . ARG B 1 173 ? 43.628 78.630 -15.292 1.00 32.76 ? 174 ARG B CB 1 ATOM 2638 C CG . ARG B 1 173 ? 42.438 77.771 -15.722 1.00 46.31 ? 174 ARG B CG 1 ATOM 2639 C CD . ARG B 1 173 ? 41.610 78.406 -16.805 1.00 58.08 ? 174 ARG B CD 1 ATOM 2640 N NE . ARG B 1 173 ? 41.499 77.498 -17.950 1.00 77.46 ? 174 ARG B NE 1 ATOM 2641 C CZ . ARG B 1 173 ? 40.370 76.922 -18.349 1.00 89.29 ? 174 ARG B CZ 1 ATOM 2642 N NH1 . ARG B 1 173 ? 39.227 77.178 -17.723 1.00 54.36 ? 174 ARG B NH1 1 ATOM 2643 N NH2 . ARG B 1 173 ? 40.370 76.110 -19.400 1.00 87.15 ? 174 ARG B NH2 1 ATOM 2644 N N . SER B 1 174 ? 46.788 78.465 -13.926 1.00 27.23 ? 175 SER B N 1 ATOM 2645 C CA . SER B 1 174 ? 47.993 79.259 -13.643 1.00 26.66 ? 175 SER B CA 1 ATOM 2646 C C . SER B 1 174 ? 48.882 79.444 -14.879 1.00 35.53 ? 175 SER B C 1 ATOM 2647 O O . SER B 1 174 ? 49.188 78.472 -15.572 1.00 37.74 ? 175 SER B O 1 ATOM 2648 C CB . SER B 1 174 ? 48.793 78.617 -12.513 1.00 27.26 ? 175 SER B CB 1 ATOM 2649 O OG . SER B 1 174 ? 49.818 79.484 -12.072 1.00 29.80 ? 175 SER B OG 1 ATOM 2650 N N . THR B 1 175 ? 49.306 80.695 -15.143 1.00 34.57 ? 176 THR B N 1 ATOM 2651 C CA . THR B 1 175 ? 50.199 81.088 -16.243 1.00 34.88 ? 176 THR B CA 1 ATOM 2652 C C . THR B 1 175 ? 51.383 81.771 -15.636 1.00 40.99 ? 176 THR B C 1 ATOM 2653 O O . THR B 1 175 ? 51.252 82.719 -14.879 1.00 39.63 ? 176 THR B O 1 ATOM 2654 C CB . THR B 1 175 ? 49.504 81.966 -17.285 1.00 40.80 ? 176 THR B CB 1 ATOM 2655 O OG1 . THR B 1 175 ? 48.319 81.303 -17.738 1.00 45.40 ? 176 THR B OG1 1 ATOM 2656 C CG2 . THR B 1 175 ? 50.425 82.296 -18.481 1.00 32.02 ? 176 THR B CG2 1 ATOM 2657 N N . CYS B 1 176 ? 52.533 81.313 -16.001 1.00 42.64 ? 177 CYS B N 1 ATOM 2658 C CA . CYS B 1 176 ? 53.708 81.778 -15.343 1.00 45.30 ? 177 CYS B CA 1 ATOM 2659 C C . CYS B 1 176 ? 54.847 82.108 -16.326 1.00 46.80 ? 177 CYS B C 1 ATOM 2660 O O . CYS B 1 176 ? 54.846 81.593 -17.437 1.00 44.02 ? 177 CYS B O 1 ATOM 2661 C CB . CYS B 1 176 ? 54.079 80.704 -14.328 1.00 48.64 ? 177 CYS B CB 1 ATOM 2662 S SG . CYS B 1 176 ? 55.046 81.300 -12.947 1.00 54.98 ? 177 CYS B SG 1 ATOM 2663 N N . HIS B 1 177 ? 55.740 83.062 -15.958 1.00 44.59 ? 178 HIS B N 1 ATOM 2664 C CA . HIS B 1 177 ? 56.864 83.538 -16.770 1.00 44.21 ? 178 HIS B CA 1 ATOM 2665 C C . HIS B 1 177 ? 58.115 83.568 -15.923 1.00 44.92 ? 178 HIS B C 1 ATOM 2666 O O . HIS B 1 177 ? 58.081 83.998 -14.770 1.00 43.12 ? 178 HIS B O 1 ATOM 2667 C CB . HIS B 1 177 ? 56.581 84.944 -17.343 1.00 46.40 ? 178 HIS B CB 1 ATOM 2668 C CG . HIS B 1 177 ? 57.726 85.517 -18.134 1.00 51.60 ? 178 HIS B CG 1 ATOM 2669 N ND1 . HIS B 1 177 ? 57.974 85.123 -19.458 1.00 54.02 ? 178 HIS B ND1 1 ATOM 2670 C CD2 . HIS B 1 177 ? 58.670 86.420 -17.767 1.00 54.56 ? 178 HIS B CD2 1 ATOM 2671 C CE1 . HIS B 1 177 ? 59.053 85.796 -19.842 1.00 53.82 ? 178 HIS B CE1 1 ATOM 2672 N NE2 . HIS B 1 177 ? 59.512 86.589 -18.864 1.00 54.50 ? 178 HIS B NE2 1 ATOM 2673 N N . TRP B 1 178 ? 59.228 83.123 -16.498 1.00 42.61 ? 179 TRP B N 1 ATOM 2674 C CA . TRP B 1 178 ? 60.512 83.144 -15.804 1.00 42.54 ? 179 TRP B CA 1 ATOM 2675 C C . TRP B 1 178 ? 61.444 84.079 -16.542 1.00 58.65 ? 179 TRP B C 1 ATOM 2676 O O . TRP B 1 178 ? 61.570 83.991 -17.769 1.00 57.63 ? 179 TRP B O 1 ATOM 2677 C CB . TRP B 1 178 ? 61.104 81.740 -15.634 1.00 37.24 ? 179 TRP B CB 1 ATOM 2678 C CG . TRP B 1 178 ? 60.297 80.865 -14.715 1.00 34.67 ? 179 TRP B CG 1 ATOM 2679 C CD1 . TRP B 1 178 ? 60.556 80.585 -13.403 1.00 36.68 ? 179 TRP B CD1 1 ATOM 2680 C CD2 . TRP B 1 178 ? 59.095 80.162 -15.048 1.00 32.69 ? 179 TRP B CD2 1 ATOM 2681 N NE1 . TRP B 1 178 ? 59.593 79.741 -12.905 1.00 34.73 ? 179 TRP B NE1 1 ATOM 2682 C CE2 . TRP B 1 178 ? 58.674 79.475 -13.888 1.00 35.49 ? 179 TRP B CE2 1 ATOM 2683 C CE3 . TRP B 1 178 ? 58.328 80.044 -16.219 1.00 32.69 ? 179 TRP B CE3 1 ATOM 2684 C CZ2 . TRP B 1 178 ? 57.508 78.686 -13.862 1.00 34.01 ? 179 TRP B CZ2 1 ATOM 2685 C CZ3 . TRP B 1 178 ? 57.180 79.268 -16.196 1.00 33.16 ? 179 TRP B CZ3 1 ATOM 2686 C CH2 . TRP B 1 178 ? 56.777 78.601 -15.031 1.00 33.42 ? 179 TRP B CH2 1 ATOM 2687 N N . GLU B 1 179 ? 62.049 85.015 -15.783 1.00 66.36 ? 180 GLU B N 1 ATOM 2688 C CA . GLU B 1 179 ? 62.944 86.061 -16.289 1.00 71.43 ? 180 GLU B CA 1 ATOM 2689 C C . GLU B 1 179 ? 64.344 85.550 -16.483 1.00 82.24 ? 180 GLU B C 1 ATOM 2690 O O . GLU B 1 179 ? 64.972 85.873 -17.496 1.00 82.05 ? 180 GLU B O 1 ATOM 2691 C CB . GLU B 1 179 ? 62.923 87.309 -15.383 1.00 73.73 ? 180 GLU B CB 1 ATOM 2692 C CG . GLU B 1 179 ? 61.614 88.089 -15.503 1.00 93.07 ? 180 GLU B CG 1 ATOM 2693 C CD . GLU B 1 179 ? 61.626 89.498 -14.943 1.00 124.30 ? 180 GLU B CD 1 ATOM 2694 O OE1 . GLU B 1 179 ? 61.785 89.652 -13.709 1.00 119.21 ? 180 GLU B OE1 1 ATOM 2695 O OE2 . GLU B 1 179 ? 61.442 90.449 -15.739 1.00 120.77 ? 180 GLU B OE2 1 ATOM 2696 N N . GLN B 1 180 ? 64.823 84.747 -15.502 1.00 83.65 ? 181 GLN B N 1 ATOM 2697 C CA . GLN B 1 180 ? 66.135 84.077 -15.465 1.00 85.05 ? 181 GLN B CA 1 ATOM 2698 C C . GLN B 1 180 ? 66.283 83.263 -16.762 1.00 89.22 ? 181 GLN B C 1 ATOM 2699 O O . GLN B 1 180 ? 65.360 82.508 -17.083 1.00 88.79 ? 181 GLN B O 1 ATOM 2700 C CB . GLN B 1 180 ? 66.196 83.115 -14.251 1.00 86.98 ? 181 GLN B CB 1 ATOM 2701 C CG . GLN B 1 180 ? 65.852 83.737 -12.893 1.00 112.74 ? 181 GLN B CG 1 ATOM 2702 C CD . GLN B 1 180 ? 67.061 84.333 -12.212 1.00 143.50 ? 181 GLN B CD 1 ATOM 2703 O OE1 . GLN B 1 180 ? 68.083 83.664 -11.987 1.00 141.48 ? 181 GLN B OE1 1 ATOM 2704 N NE2 . GLN B 1 180 ? 66.955 85.599 -11.826 1.00 138.19 ? 181 GLN B NE2 1 ATOM 2705 N N . ASN B 1 181 ? 67.377 83.458 -17.544 1.00 84.75 ? 182 ASN B N 1 ATOM 2706 C CA . ASN B 1 181 ? 67.535 82.686 -18.786 1.00 83.94 ? 182 ASN B CA 1 ATOM 2707 C C . ASN B 1 181 ? 68.184 81.290 -18.595 1.00 84.54 ? 182 ASN B C 1 ATOM 2708 O O . ASN B 1 181 ? 68.123 80.433 -19.485 1.00 83.96 ? 182 ASN B O 1 ATOM 2709 C CB . ASN B 1 181 ? 68.104 83.522 -19.931 1.00 87.49 ? 182 ASN B CB 1 ATOM 2710 C CG . ASN B 1 181 ? 67.085 84.508 -20.483 1.00 110.27 ? 182 ASN B CG 1 ATOM 2711 O OD1 . ASN B 1 181 ? 66.602 85.408 -19.782 1.00 103.76 ? 182 ASN B OD1 1 ATOM 2712 N ND2 . ASN B 1 181 ? 66.718 84.349 -21.750 1.00 99.13 ? 182 ASN B ND2 1 ATOM 2713 N N . ASN B 1 182 ? 68.707 81.056 -17.375 1.00 78.11 ? 183 ASN B N 1 ATOM 2714 C CA . ASN B 1 182 ? 69.305 79.815 -16.864 1.00 76.28 ? 183 ASN B CA 1 ATOM 2715 C C . ASN B 1 182 ? 68.211 78.755 -16.573 1.00 75.26 ? 183 ASN B C 1 ATOM 2716 O O . ASN B 1 182 ? 68.527 77.579 -16.347 1.00 75.95 ? 183 ASN B O 1 ATOM 2717 C CB . ASN B 1 182 ? 70.086 80.109 -15.573 1.00 77.66 ? 183 ASN B CB 1 ATOM 2718 C CG . ASN B 1 182 ? 69.426 81.157 -14.698 1.00 107.34 ? 183 ASN B CG 1 ATOM 2719 O OD1 . ASN B 1 182 ? 69.309 82.326 -15.093 1.00 100.15 ? 183 ASN B OD1 1 ATOM 2720 N ND2 . ASN B 1 182 ? 68.963 80.763 -13.509 1.00 100.59 ? 183 ASN B ND2 1 ATOM 2721 N N . VAL B 1 183 ? 66.931 79.186 -16.563 1.00 64.90 ? 184 VAL B N 1 ATOM 2722 C CA . VAL B 1 183 ? 65.765 78.345 -16.329 1.00 61.14 ? 184 VAL B CA 1 ATOM 2723 C C . VAL B 1 183 ? 65.321 77.805 -17.688 1.00 58.79 ? 184 VAL B C 1 ATOM 2724 O O . VAL B 1 183 ? 64.970 78.591 -18.568 1.00 57.15 ? 184 VAL B O 1 ATOM 2725 C CB . VAL B 1 183 ? 64.624 79.141 -15.610 1.00 63.61 ? 184 VAL B CB 1 ATOM 2726 C CG1 . VAL B 1 183 ? 63.328 78.345 -15.552 1.00 62.51 ? 184 VAL B CG1 1 ATOM 2727 C CG2 . VAL B 1 183 ? 65.045 79.583 -14.214 1.00 63.44 ? 184 VAL B CG2 1 ATOM 2728 N N . SER B 1 184 ? 65.319 76.469 -17.855 1.00 51.56 ? 185 SER B N 1 ATOM 2729 C CA . SER B 1 184 ? 64.879 75.864 -19.121 1.00 50.20 ? 185 SER B CA 1 ATOM 2730 C C . SER B 1 184 ? 63.705 74.905 -18.927 1.00 49.31 ? 185 SER B C 1 ATOM 2731 O O . SER B 1 184 ? 62.882 74.739 -19.824 1.00 48.97 ? 185 SER B O 1 ATOM 2732 C CB . SER B 1 184 ? 66.042 75.175 -19.836 1.00 53.97 ? 185 SER B CB 1 ATOM 2733 O OG . SER B 1 184 ? 66.802 74.379 -18.941 1.00 65.30 ? 185 SER B OG 1 ATOM 2734 N N . VAL B 1 185 ? 63.645 74.268 -17.754 1.00 42.50 ? 186 VAL B N 1 ATOM 2735 C CA . VAL B 1 185 ? 62.602 73.315 -17.384 1.00 39.82 ? 186 VAL B CA 1 ATOM 2736 C C . VAL B 1 185 ? 61.952 73.800 -16.086 1.00 39.99 ? 186 VAL B C 1 ATOM 2737 O O . VAL B 1 185 ? 62.639 74.217 -15.139 1.00 39.72 ? 186 VAL B O 1 ATOM 2738 C CB . VAL B 1 185 ? 63.132 71.847 -17.315 1.00 42.03 ? 186 VAL B CB 1 ATOM 2739 C CG1 . VAL B 1 185 ? 62.019 70.864 -16.988 1.00 40.57 ? 186 VAL B CG1 1 ATOM 2740 C CG2 . VAL B 1 185 ? 63.773 71.452 -18.639 1.00 42.46 ? 186 VAL B CG2 1 ATOM 2741 N N . VAL B 1 186 ? 60.624 73.808 -16.080 1.00 32.53 ? 187 VAL B N 1 ATOM 2742 C CA . VAL B 1 186 ? 59.816 74.208 -14.925 1.00 29.12 ? 187 VAL B CA 1 ATOM 2743 C C . VAL B 1 186 ? 58.938 73.043 -14.492 1.00 31.04 ? 187 VAL B C 1 ATOM 2744 O O . VAL B 1 186 ? 58.652 72.134 -15.282 1.00 27.39 ? 187 VAL B O 1 ATOM 2745 C CB . VAL B 1 186 ? 59.021 75.515 -15.134 1.00 29.53 ? 187 VAL B CB 1 ATOM 2746 C CG1 . VAL B 1 186 ? 59.961 76.670 -15.418 1.00 28.47 ? 187 VAL B CG1 1 ATOM 2747 C CG2 . VAL B 1 186 ? 57.985 75.376 -16.242 1.00 28.27 ? 187 VAL B CG2 1 ATOM 2748 N N . SER B 1 187 ? 58.558 73.049 -13.227 1.00 28.94 ? 188 SER B N 1 ATOM 2749 C CA . SER B 1 187 ? 57.747 71.984 -12.689 1.00 28.54 ? 188 SER B CA 1 ATOM 2750 C C . SER B 1 187 ? 56.457 72.539 -12.040 1.00 32.57 ? 188 SER B C 1 ATOM 2751 O O . SER B 1 187 ? 56.505 73.532 -11.299 1.00 31.48 ? 188 SER B O 1 ATOM 2752 C CB . SER B 1 187 ? 58.584 71.172 -11.715 1.00 30.19 ? 188 SER B CB 1 ATOM 2753 O OG . SER B 1 187 ? 57.853 70.025 -11.323 1.00 48.98 ? 188 SER B OG 1 ATOM 2754 N N . CYS B 1 188 ? 55.314 71.938 -12.379 1.00 29.89 ? 189 CYS B N 1 ATOM 2755 C CA . CYS B 1 188 ? 54.020 72.313 -11.795 1.00 30.88 ? 189 CYS B CA 1 ATOM 2756 C C . CYS B 1 188 ? 53.493 71.213 -10.912 1.00 29.09 ? 189 CYS B C 1 ATOM 2757 O O . CYS B 1 188 ? 53.325 70.082 -11.376 1.00 27.11 ? 189 CYS B O 1 ATOM 2758 C CB . CYS B 1 188 ? 52.970 72.705 -12.835 1.00 32.97 ? 189 CYS B CB 1 ATOM 2759 S SG . CYS B 1 188 ? 51.348 73.093 -12.095 1.00 37.86 ? 189 CYS B SG 1 ATOM 2760 N N . LEU B 1 189 ? 53.165 71.562 -9.670 1.00 24.35 ? 190 LEU B N 1 ATOM 2761 C CA . LEU B 1 189 ? 52.520 70.642 -8.733 1.00 24.58 ? 190 LEU B CA 1 ATOM 2762 C C . LEU B 1 189 ? 51.077 71.056 -8.518 1.00 29.27 ? 190 LEU B C 1 ATOM 2763 O O . LEU B 1 189 ? 50.807 72.202 -8.136 1.00 28.76 ? 190 LEU B O 1 ATOM 2764 C CB . LEU B 1 189 ? 53.278 70.576 -7.397 1.00 24.52 ? 190 LEU B CB 1 ATOM 2765 C CG . LEU B 1 189 ? 52.631 69.794 -6.227 1.00 29.14 ? 190 LEU B CG 1 ATOM 2766 C CD1 . LEU B 1 189 ? 52.586 68.291 -6.452 1.00 25.52 ? 190 LEU B CD1 1 ATOM 2767 C CD2 . LEU B 1 189 ? 53.320 70.136 -4.893 1.00 30.66 ? 190 LEU B CD2 1 ATOM 2768 N N . VAL B 1 190 ? 50.150 70.143 -8.817 1.00 26.87 ? 191 VAL B N 1 ATOM 2769 C CA . VAL B 1 190 ? 48.726 70.312 -8.568 1.00 25.57 ? 191 VAL B CA 1 ATOM 2770 C C . VAL B 1 190 ? 48.418 69.476 -7.301 1.00 29.68 ? 191 VAL B C 1 ATOM 2771 O O . VAL B 1 190 ? 48.283 68.254 -7.388 1.00 28.81 ? 191 VAL B O 1 ATOM 2772 C CB . VAL B 1 190 ? 47.846 69.882 -9.762 1.00 29.17 ? 191 VAL B CB 1 ATOM 2773 C CG1 . VAL B 1 190 ? 46.368 69.956 -9.399 1.00 28.03 ? 191 VAL B CG1 1 ATOM 2774 C CG2 . VAL B 1 190 ? 48.137 70.713 -11.001 1.00 29.85 ? 191 VAL B CG2 1 ATOM 2775 N N . SER B 1 191 ? 48.318 70.135 -6.138 1.00 29.19 ? 192 SER B N 1 ATOM 2776 C CA . SER B 1 191 ? 48.004 69.452 -4.861 1.00 30.02 ? 192 SER B CA 1 ATOM 2777 C C . SER B 1 191 ? 46.500 69.292 -4.664 1.00 35.17 ? 192 SER B C 1 ATOM 2778 O O . SER B 1 191 ? 45.733 70.236 -4.848 1.00 33.54 ? 192 SER B O 1 ATOM 2779 C CB . SER B 1 191 ? 48.543 70.226 -3.666 1.00 32.09 ? 192 SER B CB 1 ATOM 2780 O OG . SER B 1 191 ? 49.938 70.403 -3.798 1.00 50.12 ? 192 SER B OG 1 ATOM 2781 N N . HIS B 1 192 ? 46.098 68.116 -4.218 1.00 32.25 ? 193 HIS B N 1 ATOM 2782 C CA . HIS B 1 192 ? 44.706 67.832 -3.949 1.00 32.21 ? 193 HIS B CA 1 ATOM 2783 C C . HIS B 1 192 ? 44.616 66.691 -2.959 1.00 37.87 ? 193 HIS B C 1 ATOM 2784 O O . HIS B 1 192 ? 45.399 65.744 -3.059 1.00 38.15 ? 193 HIS B O 1 ATOM 2785 C CB . HIS B 1 192 ? 43.940 67.501 -5.245 1.00 31.54 ? 193 HIS B CB 1 ATOM 2786 C CG . HIS B 1 192 ? 42.470 67.677 -5.101 1.00 34.21 ? 193 HIS B CG 1 ATOM 2787 N ND1 . HIS B 1 192 ? 41.629 66.592 -4.943 1.00 35.83 ? 193 HIS B ND1 1 ATOM 2788 C CD2 . HIS B 1 192 ? 41.735 68.812 -5.077 1.00 35.20 ? 193 HIS B CD2 1 ATOM 2789 C CE1 . HIS B 1 192 ? 40.408 67.098 -4.834 1.00 34.65 ? 193 HIS B CE1 1 ATOM 2790 N NE2 . HIS B 1 192 ? 40.424 68.428 -4.922 1.00 35.06 ? 193 HIS B NE2 1 ATOM 2791 N N . SER B 1 193 ? 43.628 66.739 -2.048 1.00 34.04 ? 194 SER B N 1 ATOM 2792 C CA . SER B 1 193 ? 43.413 65.669 -1.058 1.00 34.27 ? 194 SER B CA 1 ATOM 2793 C C . SER B 1 193 ? 43.217 64.284 -1.692 1.00 38.81 ? 194 SER B C 1 ATOM 2794 O O . SER B 1 193 ? 43.525 63.294 -1.045 1.00 41.22 ? 194 SER B O 1 ATOM 2795 C CB . SER B 1 193 ? 42.262 66.008 -0.113 1.00 37.82 ? 194 SER B CB 1 ATOM 2796 O OG . SER B 1 193 ? 41.074 66.315 -0.823 1.00 51.43 ? 194 SER B OG 1 ATOM 2797 N N . THR B 1 194 ? 42.767 64.209 -2.959 1.00 33.43 ? 195 THR B N 1 ATOM 2798 C CA . THR B 1 194 ? 42.542 62.935 -3.657 1.00 32.22 ? 195 THR B CA 1 ATOM 2799 C C . THR B 1 194 ? 43.816 62.392 -4.334 1.00 36.24 ? 195 THR B C 1 ATOM 2800 O O . THR B 1 194 ? 43.788 61.330 -4.970 1.00 36.15 ? 195 THR B O 1 ATOM 2801 C CB . THR B 1 194 ? 41.433 63.093 -4.709 1.00 39.93 ? 195 THR B CB 1 ATOM 2802 O OG1 . THR B 1 194 ? 41.823 64.095 -5.663 1.00 40.39 ? 195 THR B OG1 1 ATOM 2803 C CG2 . THR B 1 194 ? 40.065 63.393 -4.100 1.00 33.62 ? 195 THR B CG2 1 ATOM 2804 N N . GLY B 1 195 ? 44.895 63.151 -4.246 1.00 31.84 ? 196 GLY B N 1 ATOM 2805 C CA . GLY B 1 195 ? 46.163 62.796 -4.860 1.00 30.72 ? 196 GLY B CA 1 ATOM 2806 C C . GLY B 1 195 ? 46.793 63.944 -5.622 1.00 35.44 ? 196 GLY B C 1 ATOM 2807 O O . GLY B 1 195 ? 46.118 64.655 -6.398 1.00 33.99 ? 196 GLY B O 1 ATOM 2808 N N . ASN B 1 196 ? 48.097 64.124 -5.387 1.00 31.99 ? 197 ASN B N 1 ATOM 2809 C CA . ASN B 1 196 ? 48.908 65.148 -6.030 1.00 32.27 ? 197 ASN B CA 1 ATOM 2810 C C . ASN B 1 196 ? 49.282 64.710 -7.450 1.00 36.57 ? 197 ASN B C 1 ATOM 2811 O O . ASN B 1 196 ? 49.353 63.514 -7.725 1.00 35.95 ? 197 ASN B O 1 ATOM 2812 C CB . ASN B 1 196 ? 50.141 65.417 -5.198 1.00 31.41 ? 197 ASN B CB 1 ATOM 2813 C CG . ASN B 1 196 ? 49.851 66.120 -3.921 1.00 51.61 ? 197 ASN B CG 1 ATOM 2814 O OD1 . ASN B 1 196 ? 48.717 66.492 -3.674 1.00 44.82 ? 197 ASN B OD1 1 ATOM 2815 N ND2 . ASN B 1 196 ? 50.876 66.329 -3.102 1.00 62.61 ? 197 ASN B ND2 1 ATOM 2816 N N . GLN B 1 197 ? 49.448 65.677 -8.360 1.00 32.44 ? 198 GLN B N 1 ATOM 2817 C CA . GLN B 1 197 ? 49.807 65.415 -9.767 1.00 31.50 ? 198 GLN B CA 1 ATOM 2818 C C . GLN B 1 197 ? 50.819 66.453 -10.144 1.00 34.92 ? 198 GLN B C 1 ATOM 2819 O O . GLN B 1 197 ? 50.619 67.639 -9.850 1.00 36.65 ? 198 GLN B O 1 ATOM 2820 C CB . GLN B 1 197 ? 48.578 65.538 -10.690 1.00 32.70 ? 198 GLN B CB 1 ATOM 2821 C CG . GLN B 1 197 ? 47.568 64.410 -10.519 1.00 34.66 ? 198 GLN B CG 1 ATOM 2822 C CD . GLN B 1 197 ? 46.262 64.696 -11.172 1.00 47.05 ? 198 GLN B CD 1 ATOM 2823 O OE1 . GLN B 1 197 ? 45.434 65.423 -10.629 1.00 44.13 ? 198 GLN B OE1 1 ATOM 2824 N NE2 . GLN B 1 197 ? 46.009 64.082 -12.320 1.00 35.43 ? 198 GLN B NE2 1 ATOM 2825 N N . SER B 1 198 ? 51.945 66.018 -10.718 1.00 29.34 ? 199 SER B N 1 ATOM 2826 C CA . SER B 1 198 ? 52.990 66.960 -11.125 1.00 27.73 ? 199 SER B CA 1 ATOM 2827 C C . SER B 1 198 ? 53.640 66.546 -12.412 1.00 31.83 ? 199 SER B C 1 ATOM 2828 O O . SER B 1 198 ? 53.641 65.367 -12.748 1.00 32.33 ? 199 SER B O 1 ATOM 2829 C CB . SER B 1 198 ? 54.006 67.215 -10.028 1.00 26.78 ? 199 SER B CB 1 ATOM 2830 O OG . SER B 1 198 ? 54.748 66.040 -9.794 1.00 41.07 ? 199 SER B OG 1 ATOM 2831 N N . LEU B 1 199 ? 54.117 67.532 -13.181 1.00 27.92 ? 200 LEU B N 1 ATOM 2832 C CA . LEU B 1 199 ? 54.761 67.301 -14.454 1.00 28.14 ? 200 LEU B CA 1 ATOM 2833 C C . LEU B 1 199 ? 55.688 68.451 -14.735 1.00 32.61 ? 200 LEU B C 1 ATOM 2834 O O . LEU B 1 199 ? 55.400 69.572 -14.316 1.00 31.97 ? 200 LEU B O 1 ATOM 2835 C CB . LEU B 1 199 ? 53.713 67.167 -15.570 1.00 28.50 ? 200 LEU B CB 1 ATOM 2836 C CG . LEU B 1 199 ? 54.066 66.337 -16.796 1.00 32.82 ? 200 LEU B CG 1 ATOM 2837 C CD1 . LEU B 1 199 ? 54.416 64.886 -16.421 1.00 32.92 ? 200 LEU B CD1 1 ATOM 2838 C CD2 . LEU B 1 199 ? 52.892 66.294 -17.756 1.00 31.78 ? 200 LEU B CD2 1 ATOM 2839 N N . SER B 1 200 ? 56.817 68.171 -15.426 1.00 27.94 ? 201 SER B N 1 ATOM 2840 C CA . SER B 1 200 ? 57.758 69.198 -15.855 1.00 26.59 ? 201 SER B CA 1 ATOM 2841 C C . SER B 1 200 ? 57.458 69.679 -17.289 1.00 32.12 ? 201 SER B C 1 ATOM 2842 O O . SER B 1 200 ? 56.966 68.920 -18.129 1.00 30.19 ? 201 SER B O 1 ATOM 2843 C CB . SER B 1 200 ? 59.194 68.741 -15.704 1.00 28.68 ? 201 SER B CB 1 ATOM 2844 O OG . SER B 1 200 ? 59.505 68.551 -14.334 1.00 39.73 ? 201 SER B OG 1 ATOM 2845 N N . ILE B 1 201 ? 57.680 70.967 -17.528 1.00 31.43 ? 202 ILE B N 1 ATOM 2846 C CA . ILE B 1 201 ? 57.434 71.633 -18.809 1.00 31.80 ? 202 ILE B CA 1 ATOM 2847 C C . ILE B 1 201 ? 58.745 72.271 -19.304 1.00 36.75 ? 202 ILE B C 1 ATOM 2848 O O . ILE B 1 201 ? 59.386 73.041 -18.590 1.00 36.09 ? 202 ILE B O 1 ATOM 2849 C CB . ILE B 1 201 ? 56.293 72.701 -18.694 1.00 34.53 ? 202 ILE B CB 1 ATOM 2850 C CG1 . ILE B 1 201 ? 54.994 72.141 -18.039 1.00 34.85 ? 202 ILE B CG1 1 ATOM 2851 C CG2 . ILE B 1 201 ? 55.988 73.317 -20.039 1.00 35.08 ? 202 ILE B CG2 1 ATOM 2852 C CD1 . ILE B 1 201 ? 54.020 73.221 -17.518 1.00 39.24 ? 202 ILE B CD1 1 ATOM 2853 N N . GLU B 1 202 ? 59.111 71.970 -20.539 1.00 34.86 ? 203 GLU B N 1 ATOM 2854 C CA . GLU B 1 202 ? 60.273 72.554 -21.183 1.00 35.00 ? 203 GLU B CA 1 ATOM 2855 C C . GLU B 1 202 ? 59.872 73.916 -21.758 1.00 36.05 ? 203 GLU B C 1 ATOM 2856 O O . GLU B 1 202 ? 58.956 74.018 -22.581 1.00 36.06 ? 203 GLU B O 1 ATOM 2857 C CB . GLU B 1 202 ? 60.736 71.621 -22.287 1.00 37.24 ? 203 GLU B CB 1 ATOM 2858 C CG . GLU B 1 202 ? 62.120 71.912 -22.838 1.00 59.11 ? 203 GLU B CG 1 ATOM 2859 C CD . GLU B 1 202 ? 62.471 70.998 -23.995 1.00 91.79 ? 203 GLU B CD 1 ATOM 2860 O OE1 . GLU B 1 202 ? 62.713 69.792 -23.753 1.00 91.55 ? 203 GLU B OE1 1 ATOM 2861 O OE2 . GLU B 1 202 ? 62.430 71.473 -25.152 1.00 91.35 ? 203 GLU B OE2 1 ATOM 2862 N N . LEU B 1 203 ? 60.531 74.958 -21.304 1.00 32.11 ? 204 LEU B N 1 ATOM 2863 C CA . LEU B 1 203 ? 60.268 76.310 -21.797 1.00 34.06 ? 204 LEU B CA 1 ATOM 2864 C C . LEU B 1 203 ? 60.806 76.475 -23.228 1.00 44.38 ? 204 LEU B C 1 ATOM 2865 O O . LEU B 1 203 ? 61.834 75.863 -23.569 1.00 45.26 ? 204 LEU B O 1 ATOM 2866 C CB . LEU B 1 203 ? 60.932 77.353 -20.875 1.00 33.21 ? 204 LEU B CB 1 ATOM 2867 C CG . LEU B 1 203 ? 60.433 77.422 -19.444 1.00 36.40 ? 204 LEU B CG 1 ATOM 2868 C CD1 . LEU B 1 203 ? 61.117 78.535 -18.715 1.00 37.81 ? 204 LEU B CD1 1 ATOM 2869 C CD2 . LEU B 1 203 ? 58.899 77.538 -19.374 1.00 32.21 ? 204 LEU B CD2 1 ATOM 2870 N N . SER B 1 204 ? 60.122 77.311 -24.043 1.00 41.84 ? 205 SER B N 1 ATOM 2871 C CA . SER B 1 204 ? 60.488 77.620 -25.431 1.00 69.07 ? 205 SER B CA 1 ATOM 2872 C C . SER B 1 204 ? 61.856 78.316 -25.526 1.00 98.55 ? 205 SER B C 1 ATOM 2873 O O . SER B 1 204 ? 62.283 78.995 -24.592 1.00 62.89 ? 205 SER B O 1 ATOM 2874 C CB . SER B 1 204 ? 59.414 78.483 -26.081 1.00 72.67 ? 205 SER B CB 1 ATOM 2875 O OG . SER B 1 204 ? 59.479 79.815 -25.593 1.00 81.45 ? 205 SER B OG 1 ATOM 2876 N N . VAL C 1 18 ? 64.128 67.521 -10.629 1.00 68.83 ? 19 VAL C N 1 ATOM 2877 C CA . VAL C 1 18 ? 62.840 67.192 -9.988 1.00 67.52 ? 19 VAL C CA 1 ATOM 2878 C C . VAL C 1 18 ? 62.399 65.770 -10.403 1.00 66.91 ? 19 VAL C C 1 ATOM 2879 O O . VAL C 1 18 ? 62.253 65.464 -11.602 1.00 66.04 ? 19 VAL C O 1 ATOM 2880 C CB . VAL C 1 18 ? 61.696 68.246 -10.176 1.00 70.89 ? 19 VAL C CB 1 ATOM 2881 C CG1 . VAL C 1 18 ? 60.436 67.824 -9.413 1.00 70.58 ? 19 VAL C CG1 1 ATOM 2882 C CG2 . VAL C 1 18 ? 62.134 69.639 -9.742 1.00 70.64 ? 19 VAL C CG2 1 ATOM 2883 N N . ASN C 1 19 ? 62.200 64.914 -9.392 1.00 58.99 ? 20 ASN C N 1 ATOM 2884 C CA . ASN C 1 19 ? 61.820 63.533 -9.605 1.00 56.72 ? 20 ASN C CA 1 ATOM 2885 C C . ASN C 1 19 ? 61.009 62.918 -8.475 1.00 55.50 ? 20 ASN C C 1 ATOM 2886 O O . ASN C 1 19 ? 60.982 63.417 -7.343 1.00 55.75 ? 20 ASN C O 1 ATOM 2887 C CB . ASN C 1 19 ? 63.076 62.690 -9.885 1.00 59.60 ? 20 ASN C CB 1 ATOM 2888 C CG . ASN C 1 19 ? 63.892 62.321 -8.663 1.00 97.67 ? 20 ASN C CG 1 ATOM 2889 O OD1 . ASN C 1 19 ? 63.532 61.406 -7.908 1.00 78.41 ? 20 ASN C OD1 1 ATOM 2890 N ND2 . ASN C 1 19 ? 65.017 63.014 -8.457 1.00 110.59 ? 20 ASN C ND2 1 ATOM 2891 N N . THR C 1 20 ? 60.405 61.773 -8.783 1.00 47.98 ? 21 THR C N 1 ATOM 2892 C CA . THR C 1 20 ? 59.704 60.925 -7.831 1.00 44.96 ? 21 THR C CA 1 ATOM 2893 C C . THR C 1 20 ? 60.663 59.778 -7.462 1.00 42.13 ? 21 THR C C 1 ATOM 2894 O O . THR C 1 20 ? 61.098 59.048 -8.339 1.00 40.16 ? 21 THR C O 1 ATOM 2895 C CB . THR C 1 20 ? 58.410 60.388 -8.473 1.00 46.31 ? 21 THR C CB 1 ATOM 2896 O OG1 . THR C 1 20 ? 57.652 61.470 -8.983 1.00 50.28 ? 21 THR C OG1 1 ATOM 2897 C CG2 . THR C 1 20 ? 57.551 59.589 -7.517 1.00 36.19 ? 21 THR C CG2 1 ATOM 2898 N N . THR C 1 21 ? 61.004 59.632 -6.181 1.00 39.20 ? 22 THR C N 1 ATOM 2899 C CA . THR C 1 21 ? 61.778 58.486 -5.726 1.00 38.22 ? 22 THR C CA 1 ATOM 2900 C C . THR C 1 21 ? 60.792 57.360 -5.499 1.00 40.36 ? 22 THR C C 1 ATOM 2901 O O . THR C 1 21 ? 59.743 57.570 -4.909 1.00 41.58 ? 22 THR C O 1 ATOM 2902 C CB . THR C 1 21 ? 62.670 58.805 -4.537 1.00 47.48 ? 22 THR C CB 1 ATOM 2903 O OG1 . THR C 1 21 ? 63.586 59.823 -4.941 1.00 57.85 ? 22 THR C OG1 1 ATOM 2904 C CG2 . THR C 1 21 ? 63.504 57.603 -4.114 1.00 45.67 ? 22 THR C CG2 1 ATOM 2905 N N . MET C 1 22 ? 61.089 56.199 -6.039 1.00 36.16 ? 23 MET C N 1 ATOM 2906 C CA . MET C 1 22 ? 60.236 55.031 -5.931 1.00 36.38 ? 23 MET C CA 1 ATOM 2907 C C . MET C 1 22 ? 61.097 53.850 -5.442 1.00 40.03 ? 23 MET C C 1 ATOM 2908 O O . MET C 1 22 ? 62.175 53.615 -5.986 1.00 40.57 ? 23 MET C O 1 ATOM 2909 C CB . MET C 1 22 ? 59.628 54.737 -7.302 1.00 39.41 ? 23 MET C CB 1 ATOM 2910 C CG . MET C 1 22 ? 58.589 53.681 -7.261 1.00 45.59 ? 23 MET C CG 1 ATOM 2911 S SD . MET C 1 22 ? 57.824 53.437 -8.854 1.00 52.87 ? 23 MET C SD 1 ATOM 2912 C CE . MET C 1 22 ? 56.433 54.715 -8.728 1.00 50.02 ? 23 MET C CE 1 ATOM 2913 N N . SER C 1 23 ? 60.635 53.143 -4.397 1.00 35.53 ? 24 SER C N 1 ATOM 2914 C CA . SER C 1 23 ? 61.311 51.970 -3.839 1.00 33.91 ? 24 SER C CA 1 ATOM 2915 C C . SER C 1 23 ? 60.459 50.772 -4.114 1.00 34.21 ? 24 SER C C 1 ATOM 2916 O O . SER C 1 23 ? 59.263 50.802 -3.865 1.00 34.81 ? 24 SER C O 1 ATOM 2917 C CB . SER C 1 23 ? 61.534 52.128 -2.342 1.00 35.67 ? 24 SER C CB 1 ATOM 2918 O OG . SER C 1 23 ? 62.587 53.053 -2.141 1.00 47.26 ? 24 SER C OG 1 ATOM 2919 N N . VAL C 1 24 ? 61.025 49.765 -4.733 1.00 28.64 ? 25 VAL C N 1 ATOM 2920 C CA . VAL C 1 24 ? 60.268 48.558 -5.073 1.00 28.01 ? 25 VAL C CA 1 ATOM 2921 C C . VAL C 1 24 ? 61.082 47.360 -4.650 1.00 30.76 ? 25 VAL C C 1 ATOM 2922 O O . VAL C 1 24 ? 62.309 47.321 -4.809 1.00 30.64 ? 25 VAL C O 1 ATOM 2923 C CB . VAL C 1 24 ? 59.788 48.465 -6.564 1.00 31.28 ? 25 VAL C CB 1 ATOM 2924 C CG1 . VAL C 1 24 ? 58.945 47.219 -6.791 1.00 29.58 ? 25 VAL C CG1 1 ATOM 2925 C CG2 . VAL C 1 24 ? 58.968 49.687 -6.943 1.00 31.61 ? 25 VAL C CG2 1 ATOM 2926 N N . GLN C 1 25 ? 60.381 46.403 -4.075 1.00 26.06 ? 26 GLN C N 1 ATOM 2927 C CA . GLN C 1 25 ? 60.964 45.193 -3.558 1.00 27.58 ? 26 GLN C CA 1 ATOM 2928 C C . GLN C 1 25 ? 61.202 44.193 -4.701 1.00 32.75 ? 26 GLN C C 1 ATOM 2929 O O . GLN C 1 25 ? 60.410 44.085 -5.630 1.00 30.04 ? 26 GLN C O 1 ATOM 2930 C CB . GLN C 1 25 ? 60.000 44.648 -2.503 1.00 28.94 ? 26 GLN C CB 1 ATOM 2931 C CG . GLN C 1 25 ? 60.645 43.960 -1.344 1.00 48.36 ? 26 GLN C CG 1 ATOM 2932 C CD . GLN C 1 25 ? 59.655 43.615 -0.278 1.00 52.19 ? 26 GLN C CD 1 ATOM 2933 O OE1 . GLN C 1 25 ? 59.166 44.479 0.468 1.00 42.50 ? 26 GLN C OE1 1 ATOM 2934 N NE2 . GLN C 1 25 ? 59.391 42.322 -0.170 1.00 38.56 ? 26 GLN C NE2 1 ATOM 2935 N N . MET C 1 26 ? 62.341 43.532 -4.677 1.00 31.94 ? 27 MET C N 1 ATOM 2936 C CA . MET C 1 26 ? 62.703 42.492 -5.642 1.00 31.16 ? 27 MET C CA 1 ATOM 2937 C C . MET C 1 26 ? 61.525 41.489 -5.877 1.00 33.04 ? 27 MET C C 1 ATOM 2938 O O . MET C 1 26 ? 60.877 41.077 -4.906 1.00 30.52 ? 27 MET C O 1 ATOM 2939 C CB . MET C 1 26 ? 63.918 41.765 -5.078 1.00 33.66 ? 27 MET C CB 1 ATOM 2940 C CG . MET C 1 26 ? 64.407 40.666 -5.927 1.00 38.58 ? 27 MET C CG 1 ATOM 2941 S SD . MET C 1 26 ? 66.094 41.000 -6.352 1.00 43.50 ? 27 MET C SD 1 ATOM 2942 C CE . MET C 1 26 ? 66.331 39.750 -7.529 1.00 40.16 ? 27 MET C CE 1 ATOM 2943 N N . ASP C 1 27 ? 61.265 41.108 -7.169 1.00 31.29 ? 28 ASP C N 1 ATOM 2944 C CA . ASP C 1 27 ? 60.215 40.174 -7.628 1.00 32.73 ? 28 ASP C CA 1 ATOM 2945 C C . ASP C 1 27 ? 58.803 40.731 -7.686 1.00 36.91 ? 28 ASP C C 1 ATOM 2946 O O . ASP C 1 27 ? 57.903 40.067 -8.216 1.00 38.04 ? 28 ASP C O 1 ATOM 2947 C CB . ASP C 1 27 ? 60.232 38.826 -6.863 1.00 35.47 ? 28 ASP C CB 1 ATOM 2948 C CG . ASP C 1 27 ? 61.548 38.121 -6.964 1.00 51.38 ? 28 ASP C CG 1 ATOM 2949 O OD1 . ASP C 1 27 ? 62.063 37.992 -8.106 1.00 54.39 ? 28 ASP C OD1 1 ATOM 2950 O OD2 . ASP C 1 27 ? 62.091 37.735 -5.907 1.00 56.09 ? 28 ASP C OD2 1 ATOM 2951 N N . LYS C 1 28 ? 58.599 41.933 -7.163 1.00 32.37 ? 29 LYS C N 1 ATOM 2952 C CA . LYS C 1 28 ? 57.293 42.572 -7.202 1.00 31.59 ? 29 LYS C CA 1 ATOM 2953 C C . LYS C 1 28 ? 57.155 43.326 -8.528 1.00 34.95 ? 29 LYS C C 1 ATOM 2954 O O . LYS C 1 28 ? 58.152 43.558 -9.215 1.00 35.50 ? 29 LYS C O 1 ATOM 2955 C CB . LYS C 1 28 ? 57.125 43.524 -6.010 1.00 33.50 ? 29 LYS C CB 1 ATOM 2956 C CG . LYS C 1 28 ? 57.396 42.902 -4.621 1.00 40.51 ? 29 LYS C CG 1 ATOM 2957 C CD . LYS C 1 28 ? 56.382 41.857 -4.192 1.00 51.43 ? 29 LYS C CD 1 ATOM 2958 C CE . LYS C 1 28 ? 56.360 41.721 -2.690 1.00 72.99 ? 29 LYS C CE 1 ATOM 2959 N NZ . LYS C 1 28 ? 54.968 41.515 -2.153 1.00 87.84 ? 29 LYS C NZ 1 ATOM 2960 N N . LYS C 1 29 ? 55.925 43.690 -8.890 1.00 29.80 ? 30 LYS C N 1 ATOM 2961 C CA . LYS C 1 29 ? 55.615 44.441 -10.097 1.00 28.91 ? 30 LYS C CA 1 ATOM 2962 C C . LYS C 1 29 ? 55.763 45.960 -9.804 1.00 32.10 ? 30 LYS C C 1 ATOM 2963 O O . LYS C 1 29 ? 55.421 46.407 -8.714 1.00 31.85 ? 30 LYS C O 1 ATOM 2964 C CB . LYS C 1 29 ? 54.184 44.089 -10.538 1.00 31.94 ? 30 LYS C CB 1 ATOM 2965 C CG . LYS C 1 29 ? 53.678 44.840 -11.756 1.00 44.73 ? 30 LYS C CG 1 ATOM 2966 C CD . LYS C 1 29 ? 52.396 44.251 -12.290 1.00 53.23 ? 30 LYS C CD 1 ATOM 2967 C CE . LYS C 1 29 ? 51.209 45.108 -11.980 1.00 72.83 ? 30 LYS C CE 1 ATOM 2968 N NZ . LYS C 1 29 ? 50.108 44.875 -12.954 1.00 90.07 ? 30 LYS C NZ 1 ATOM 2969 N N . ALA C 1 30 ? 56.350 46.723 -10.735 1.00 27.53 ? 31 ALA C N 1 ATOM 2970 C CA . ALA C 1 30 ? 56.469 48.184 -10.623 1.00 26.81 ? 31 ALA C CA 1 ATOM 2971 C C . ALA C 1 30 ? 55.632 48.836 -11.720 1.00 29.78 ? 31 ALA C C 1 ATOM 2972 O O . ALA C 1 30 ? 55.571 48.326 -12.831 1.00 27.64 ? 31 ALA C O 1 ATOM 2973 C CB . ALA C 1 30 ? 57.921 48.634 -10.738 1.00 27.45 ? 31 ALA C CB 1 ATOM 2974 N N . LEU C 1 31 ? 54.934 49.920 -11.389 1.00 29.69 ? 32 LEU C N 1 ATOM 2975 C CA . LEU C 1 31 ? 54.150 50.696 -12.343 1.00 29.61 ? 32 LEU C CA 1 ATOM 2976 C C . LEU C 1 31 ? 54.565 52.130 -12.238 1.00 34.11 ? 32 LEU C C 1 ATOM 2977 O O . LEU C 1 31 ? 54.524 52.700 -11.155 1.00 33.39 ? 32 LEU C O 1 ATOM 2978 C CB . LEU C 1 31 ? 52.654 50.530 -12.137 1.00 29.44 ? 32 LEU C CB 1 ATOM 2979 C CG . LEU C 1 31 ? 52.072 49.155 -12.549 1.00 33.41 ? 32 LEU C CG 1 ATOM 2980 C CD1 . LEU C 1 31 ? 50.686 48.982 -11.960 1.00 30.69 ? 32 LEU C CD1 1 ATOM 2981 C CD2 . LEU C 1 31 ? 52.078 48.966 -14.084 1.00 30.49 ? 32 LEU C CD2 1 ATOM 2982 N N . LEU C 1 32 ? 55.055 52.690 -13.340 1.00 33.36 ? 33 LEU C N 1 ATOM 2983 C CA . LEU C 1 32 ? 55.546 54.071 -13.377 1.00 34.33 ? 33 LEU C CA 1 ATOM 2984 C C . LEU C 1 32 ? 54.609 54.866 -14.241 1.00 39.27 ? 33 LEU C C 1 ATOM 2985 O O . LEU C 1 32 ? 54.493 54.612 -15.425 1.00 38.52 ? 33 LEU C O 1 ATOM 2986 C CB . LEU C 1 32 ? 56.999 54.123 -13.895 1.00 34.05 ? 33 LEU C CB 1 ATOM 2987 C CG . LEU C 1 32 ? 58.106 53.692 -12.924 1.00 38.85 ? 33 LEU C CG 1 ATOM 2988 C CD1 . LEU C 1 32 ? 58.121 52.205 -12.686 1.00 39.58 ? 33 LEU C CD1 1 ATOM 2989 C CD2 . LEU C 1 32 ? 59.434 53.990 -13.503 1.00 42.11 ? 33 LEU C CD2 1 ATOM 2990 N N . CYS C 1 33 ? 53.849 55.735 -13.617 1.00 40.41 ? 34 CYS C N 1 ATOM 2991 C CA . CYS C 1 33 ? 52.838 56.526 -14.288 1.00 42.89 ? 34 CYS C CA 1 ATOM 2992 C C . CYS C 1 33 ? 53.453 57.750 -14.922 1.00 43.83 ? 34 CYS C C 1 ATOM 2993 O O . CYS C 1 33 ? 54.115 58.553 -14.259 1.00 42.38 ? 34 CYS C O 1 ATOM 2994 C CB . CYS C 1 33 ? 51.720 56.895 -13.323 1.00 45.86 ? 34 CYS C CB 1 ATOM 2995 S SG . CYS C 1 33 ? 50.341 57.762 -14.102 1.00 52.13 ? 34 CYS C SG 1 ATOM 2996 N N . CYS C 1 34 ? 53.222 57.921 -16.197 1.00 38.98 ? 35 CYS C N 1 ATOM 2997 C CA . CYS C 1 34 ? 53.774 59.093 -16.848 1.00 38.68 ? 35 CYS C CA 1 ATOM 2998 C C . CYS C 1 34 ? 52.924 60.366 -16.513 1.00 39.40 ? 35 CYS C C 1 ATOM 2999 O O . CYS C 1 34 ? 53.452 61.378 -16.042 1.00 39.03 ? 35 CYS C O 1 ATOM 3000 C CB . CYS C 1 34 ? 53.902 58.839 -18.339 1.00 39.86 ? 35 CYS C CB 1 ATOM 3001 S SG . CYS C 1 34 ? 54.750 60.151 -19.183 1.00 44.55 ? 35 CYS C SG 1 ATOM 3002 N N . PHE C 1 35 ? 51.597 60.250 -16.652 1.00 34.11 ? 36 PHE C N 1 ATOM 3003 C CA . PHE C 1 35 ? 50.559 61.227 -16.288 1.00 32.65 ? 36 PHE C CA 1 ATOM 3004 C C . PHE C 1 35 ? 49.246 60.492 -16.401 1.00 36.25 ? 36 PHE C C 1 ATOM 3005 O O . PHE C 1 35 ? 49.183 59.458 -17.070 1.00 36.94 ? 36 PHE C O 1 ATOM 3006 C CB . PHE C 1 35 ? 50.556 62.471 -17.219 1.00 34.37 ? 36 PHE C CB 1 ATOM 3007 C CG . PHE C 1 35 ? 50.255 62.203 -18.681 1.00 35.44 ? 36 PHE C CG 1 ATOM 3008 C CD1 . PHE C 1 35 ? 48.949 61.961 -19.108 1.00 36.99 ? 36 PHE C CD1 1 ATOM 3009 C CD2 . PHE C 1 35 ? 51.275 62.227 -19.635 1.00 36.74 ? 36 PHE C CD2 1 ATOM 3010 C CE1 . PHE C 1 35 ? 48.678 61.680 -20.446 1.00 37.01 ? 36 PHE C CE1 1 ATOM 3011 C CE2 . PHE C 1 35 ? 51.001 61.974 -20.977 1.00 38.94 ? 36 PHE C CE2 1 ATOM 3012 C CZ . PHE C 1 35 ? 49.704 61.703 -21.376 1.00 36.98 ? 36 PHE C CZ 1 ATOM 3013 N N . SER C 1 36 ? 48.191 61.015 -15.784 1.00 35.06 ? 37 SER C N 1 ATOM 3014 C CA . SER C 1 36 ? 46.861 60.416 -15.924 1.00 35.33 ? 37 SER C CA 1 ATOM 3015 C C . SER C 1 36 ? 45.871 61.529 -16.083 1.00 41.00 ? 37 SER C C 1 ATOM 3016 O O . SER C 1 36 ? 45.471 62.140 -15.091 1.00 42.71 ? 37 SER C O 1 ATOM 3017 C CB . SER C 1 36 ? 46.499 59.538 -14.740 1.00 37.99 ? 37 SER C CB 1 ATOM 3018 O OG . SER C 1 36 ? 45.341 58.801 -15.096 1.00 41.74 ? 37 SER C OG 1 ATOM 3019 N N . SER C 1 37 ? 45.541 61.858 -17.333 1.00 36.42 ? 38 SER C N 1 ATOM 3020 C CA . SER C 1 37 ? 44.626 62.950 -17.636 1.00 35.78 ? 38 SER C CA 1 ATOM 3021 C C . SER C 1 37 ? 44.063 62.821 -19.045 1.00 42.85 ? 38 SER C C 1 ATOM 3022 O O . SER C 1 37 ? 44.833 62.673 -19.996 1.00 43.34 ? 38 SER C O 1 ATOM 3023 C CB . SER C 1 37 ? 45.342 64.290 -17.514 1.00 36.36 ? 38 SER C CB 1 ATOM 3024 O OG . SER C 1 37 ? 44.470 65.358 -17.839 1.00 37.65 ? 38 SER C OG 1 ATOM 3025 N N . PRO C 1 38 ? 42.743 62.986 -19.228 1.00 40.50 ? 39 PRO C N 1 ATOM 3026 C CA . PRO C 1 38 ? 42.194 62.982 -20.606 1.00 40.38 ? 39 PRO C CA 1 ATOM 3027 C C . PRO C 1 38 ? 42.494 64.290 -21.372 1.00 45.32 ? 39 PRO C C 1 ATOM 3028 O O . PRO C 1 38 ? 42.280 64.367 -22.585 1.00 46.10 ? 39 PRO C O 1 ATOM 3029 C CB . PRO C 1 38 ? 40.691 62.809 -20.378 1.00 41.66 ? 39 PRO C CB 1 ATOM 3030 C CG . PRO C 1 38 ? 40.436 63.434 -19.042 1.00 45.43 ? 39 PRO C CG 1 ATOM 3031 C CD . PRO C 1 38 ? 41.681 63.195 -18.216 1.00 41.61 ? 39 PRO C CD 1 ATOM 3032 N N . LEU C 1 39 ? 43.039 65.292 -20.680 1.00 40.90 ? 40 LEU C N 1 ATOM 3033 C CA . LEU C 1 39 ? 43.308 66.607 -21.247 1.00 40.61 ? 40 LEU C CA 1 ATOM 3034 C C . LEU C 1 39 ? 44.669 66.793 -21.889 1.00 45.09 ? 40 LEU C C 1 ATOM 3035 O O . LEU C 1 39 ? 44.864 67.787 -22.586 1.00 45.47 ? 40 LEU C O 1 ATOM 3036 C CB . LEU C 1 39 ? 43.065 67.708 -20.189 1.00 40.45 ? 40 LEU C CB 1 ATOM 3037 C CG . LEU C 1 39 ? 41.742 67.683 -19.384 1.00 43.94 ? 40 LEU C CG 1 ATOM 3038 C CD1 . LEU C 1 39 ? 41.665 68.906 -18.487 1.00 43.06 ? 40 LEU C CD1 1 ATOM 3039 C CD2 . LEU C 1 39 ? 40.494 67.593 -20.315 1.00 44.26 ? 40 LEU C CD2 1 ATOM 3040 N N . ILE C 1 40 ? 45.627 65.900 -21.624 1.00 42.80 ? 41 ILE C N 1 ATOM 3041 C CA . ILE C 1 40 ? 46.971 66.037 -22.208 1.00 42.73 ? 41 ILE C CA 1 ATOM 3042 C C . ILE C 1 40 ? 46.978 65.420 -23.618 1.00 50.92 ? 41 ILE C C 1 ATOM 3043 O O . ILE C 1 40 ? 46.757 64.227 -23.753 1.00 50.09 ? 41 ILE C O 1 ATOM 3044 C CB . ILE C 1 40 ? 48.096 65.520 -21.249 1.00 44.00 ? 41 ILE C CB 1 ATOM 3045 C CG1 . ILE C 1 40 ? 48.125 66.386 -19.940 1.00 43.18 ? 41 ILE C CG1 1 ATOM 3046 C CG2 . ILE C 1 40 ? 49.493 65.507 -21.962 1.00 41.40 ? 41 ILE C CG2 1 ATOM 3047 C CD1 . ILE C 1 40 ? 48.679 65.721 -18.753 1.00 49.30 ? 41 ILE C CD1 1 ATOM 3048 N N . ASN C 1 41 ? 47.154 66.209 -24.674 1.00 51.56 ? 42 ASN C N 1 ATOM 3049 C CA . ASN C 1 41 ? 47.100 65.518 -25.965 1.00 53.49 ? 42 ASN C CA 1 ATOM 3050 C C . ASN C 1 41 ? 48.462 65.182 -26.533 1.00 55.76 ? 42 ASN C C 1 ATOM 3051 O O . ASN C 1 41 ? 49.055 65.946 -27.305 1.00 57.80 ? 42 ASN C O 1 ATOM 3052 C CB . ASN C 1 41 ? 46.046 66.095 -26.938 1.00 64.72 ? 42 ASN C CB 1 ATOM 3053 C CG . ASN C 1 41 ? 44.637 66.155 -26.318 1.00 98.91 ? 42 ASN C CG 1 ATOM 3054 O OD1 . ASN C 1 41 ? 44.085 67.248 -26.059 1.00 96.02 ? 42 ASN C OD1 1 ATOM 3055 N ND2 . ASN C 1 41 ? 44.047 64.984 -26.001 1.00 85.12 ? 42 ASN C ND2 1 ATOM 3056 N N . ALA C 1 42 ? 48.990 64.061 -26.031 1.00 47.62 ? 43 ALA C N 1 ATOM 3057 C CA . ALA C 1 42 ? 50.308 63.536 -26.350 1.00 45.67 ? 43 ALA C CA 1 ATOM 3058 C C . ALA C 1 42 ? 50.365 62.945 -27.760 1.00 47.43 ? 43 ALA C C 1 ATOM 3059 O O . ALA C 1 42 ? 49.517 62.126 -28.125 1.00 48.86 ? 43 ALA C O 1 ATOM 3060 C CB . ALA C 1 42 ? 50.699 62.493 -25.330 1.00 45.62 ? 43 ALA C CB 1 ATOM 3061 N N . VAL C 1 43 ? 51.353 63.358 -28.549 1.00 40.51 ? 44 VAL C N 1 ATOM 3062 C CA . VAL C 1 43 ? 51.525 62.818 -29.893 1.00 40.21 ? 44 VAL C CA 1 ATOM 3063 C C . VAL C 1 43 ? 52.538 61.651 -29.865 1.00 41.46 ? 44 VAL C C 1 ATOM 3064 O O . VAL C 1 43 ? 52.268 60.576 -30.413 1.00 41.90 ? 44 VAL C O 1 ATOM 3065 C CB . VAL C 1 43 ? 51.734 63.883 -31.018 1.00 44.68 ? 44 VAL C CB 1 ATOM 3066 C CG1 . VAL C 1 43 ? 50.742 65.037 -30.866 1.00 44.36 ? 44 VAL C CG1 1 ATOM 3067 C CG2 . VAL C 1 43 ? 53.153 64.414 -31.058 1.00 44.66 ? 44 VAL C CG2 1 ATOM 3068 N N . LEU C 1 44 ? 53.628 61.837 -29.115 1.00 35.22 ? 45 LEU C N 1 ATOM 3069 C CA . LEU C 1 44 ? 54.700 60.876 -28.903 1.00 34.44 ? 45 LEU C CA 1 ATOM 3070 C C . LEU C 1 44 ? 55.042 60.771 -27.399 1.00 36.09 ? 45 LEU C C 1 ATOM 3071 O O . LEU C 1 44 ? 55.243 61.791 -26.739 1.00 35.03 ? 45 LEU C O 1 ATOM 3072 C CB . LEU C 1 44 ? 55.952 61.305 -29.716 1.00 34.09 ? 45 LEU C CB 1 ATOM 3073 C CG . LEU C 1 44 ? 57.164 60.321 -29.701 1.00 38.61 ? 45 LEU C CG 1 ATOM 3074 C CD1 . LEU C 1 44 ? 56.839 58.997 -30.401 1.00 37.41 ? 45 LEU C CD1 1 ATOM 3075 C CD2 . LEU C 1 44 ? 58.432 60.971 -30.292 1.00 38.34 ? 45 LEU C CD2 1 ATOM 3076 N N . ILE C 1 45 ? 55.144 59.546 -26.880 1.00 32.18 ? 46 ILE C N 1 ATOM 3077 C CA . ILE C 1 45 ? 55.555 59.274 -25.491 1.00 31.79 ? 46 ILE C CA 1 ATOM 3078 C C . ILE C 1 45 ? 56.764 58.347 -25.519 1.00 33.83 ? 46 ILE C C 1 ATOM 3079 O O . ILE C 1 45 ? 56.703 57.276 -26.098 1.00 32.89 ? 46 ILE C O 1 ATOM 3080 C CB . ILE C 1 45 ? 54.395 58.735 -24.604 1.00 35.42 ? 46 ILE C CB 1 ATOM 3081 C CG1 . ILE C 1 45 ? 53.247 59.764 -24.509 1.00 36.58 ? 46 ILE C CG1 1 ATOM 3082 C CG2 . ILE C 1 45 ? 54.911 58.368 -23.200 1.00 33.75 ? 46 ILE C CG2 1 ATOM 3083 C CD1 . ILE C 1 45 ? 51.964 59.211 -24.038 1.00 55.67 ? 46 ILE C CD1 1 ATOM 3084 N N . THR C 1 46 ? 57.852 58.746 -24.898 1.00 31.38 ? 47 THR C N 1 ATOM 3085 C CA . THR C 1 46 ? 59.085 57.957 -24.875 1.00 30.05 ? 47 THR C CA 1 ATOM 3086 C C . THR C 1 46 ? 59.591 57.782 -23.452 1.00 33.70 ? 47 THR C C 1 ATOM 3087 O O . THR C 1 46 ? 59.754 58.766 -22.741 1.00 34.55 ? 47 THR C O 1 ATOM 3088 C CB . THR C 1 46 ? 60.156 58.720 -25.715 1.00 35.79 ? 47 THR C CB 1 ATOM 3089 O OG1 . THR C 1 46 ? 59.678 58.887 -27.039 1.00 40.40 ? 47 THR C OG1 1 ATOM 3090 C CG2 . THR C 1 46 ? 61.511 58.049 -25.738 1.00 31.86 ? 47 THR C CG2 1 ATOM 3091 N N . TRP C 1 47 ? 59.955 56.556 -23.071 1.00 29.92 ? 48 TRP C N 1 ATOM 3092 C CA . TRP C 1 47 ? 60.616 56.307 -21.790 1.00 28.23 ? 48 TRP C CA 1 ATOM 3093 C C . TRP C 1 47 ? 62.090 56.081 -22.072 1.00 30.79 ? 48 TRP C C 1 ATOM 3094 O O . TRP C 1 47 ? 62.404 55.253 -22.894 1.00 32.02 ? 48 TRP C O 1 ATOM 3095 C CB . TRP C 1 47 ? 60.016 55.079 -21.066 1.00 26.82 ? 48 TRP C CB 1 ATOM 3096 C CG . TRP C 1 47 ? 58.681 55.302 -20.398 1.00 27.03 ? 48 TRP C CG 1 ATOM 3097 C CD1 . TRP C 1 47 ? 57.444 55.001 -20.901 1.00 29.52 ? 48 TRP C CD1 1 ATOM 3098 C CD2 . TRP C 1 47 ? 58.463 55.812 -19.075 1.00 26.38 ? 48 TRP C CD2 1 ATOM 3099 N NE1 . TRP C 1 47 ? 56.472 55.283 -19.972 1.00 28.72 ? 48 TRP C NE1 1 ATOM 3100 C CE2 . TRP C 1 47 ? 57.066 55.802 -18.846 1.00 29.89 ? 48 TRP C CE2 1 ATOM 3101 C CE3 . TRP C 1 47 ? 59.318 56.237 -18.044 1.00 27.27 ? 48 TRP C CE3 1 ATOM 3102 C CZ2 . TRP C 1 47 ? 56.504 56.196 -17.622 1.00 29.46 ? 48 TRP C CZ2 1 ATOM 3103 C CZ3 . TRP C 1 47 ? 58.756 56.680 -16.845 1.00 28.56 ? 48 TRP C CZ3 1 ATOM 3104 C CH2 . TRP C 1 47 ? 57.368 56.674 -16.648 1.00 29.06 ? 48 TRP C CH2 1 ATOM 3105 N N . ILE C 1 48 ? 62.991 56.819 -21.420 1.00 28.42 ? 49 ILE C N 1 ATOM 3106 C CA . ILE C 1 48 ? 64.446 56.622 -21.504 1.00 28.48 ? 49 ILE C CA 1 ATOM 3107 C C . ILE C 1 48 ? 64.866 56.052 -20.146 1.00 32.23 ? 49 ILE C C 1 ATOM 3108 O O . ILE C 1 48 ? 64.582 56.665 -19.105 1.00 30.70 ? 49 ILE C O 1 ATOM 3109 C CB . ILE C 1 48 ? 65.232 57.911 -21.860 1.00 32.98 ? 49 ILE C CB 1 ATOM 3110 C CG1 . ILE C 1 48 ? 64.808 58.445 -23.249 1.00 35.83 ? 49 ILE C CG1 1 ATOM 3111 C CG2 . ILE C 1 48 ? 66.751 57.680 -21.829 1.00 29.64 ? 49 ILE C CG2 1 ATOM 3112 C CD1 . ILE C 1 48 ? 63.956 59.606 -23.165 1.00 43.90 ? 49 ILE C CD1 1 ATOM 3113 N N . ILE C 1 49 ? 65.497 54.855 -20.164 1.00 26.30 ? 50 ILE C N 1 ATOM 3114 C CA . ILE C 1 49 ? 65.895 54.122 -18.970 1.00 23.96 ? 50 ILE C CA 1 ATOM 3115 C C . ILE C 1 49 ? 67.408 54.084 -18.872 1.00 29.32 ? 50 ILE C C 1 ATOM 3116 O O . ILE C 1 49 ? 68.054 53.559 -19.762 1.00 30.63 ? 50 ILE C O 1 ATOM 3117 C CB . ILE C 1 49 ? 65.237 52.727 -18.972 1.00 25.79 ? 50 ILE C CB 1 ATOM 3118 C CG1 . ILE C 1 49 ? 63.701 52.842 -19.072 1.00 25.57 ? 50 ILE C CG1 1 ATOM 3119 C CG2 . ILE C 1 49 ? 65.649 51.947 -17.752 1.00 27.26 ? 50 ILE C CG2 1 ATOM 3120 C CD1 . ILE C 1 49 ? 63.048 51.973 -20.036 1.00 27.03 ? 50 ILE C CD1 1 ATOM 3121 N N . LYS C 1 50 ? 67.961 54.651 -17.800 1.00 26.21 ? 51 LYS C N 1 ATOM 3122 C CA . LYS C 1 50 ? 69.391 54.785 -17.530 1.00 25.14 ? 51 LYS C CA 1 ATOM 3123 C C . LYS C 1 50 ? 69.822 54.110 -16.245 1.00 28.50 ? 51 LYS C C 1 ATOM 3124 O O . LYS C 1 50 ? 69.144 54.172 -15.229 1.00 28.06 ? 51 LYS C O 1 ATOM 3125 C CB . LYS C 1 50 ? 69.808 56.277 -17.519 1.00 27.95 ? 51 LYS C CB 1 ATOM 3126 C CG . LYS C 1 50 ? 69.634 56.968 -18.837 1.00 43.69 ? 51 LYS C CG 1 ATOM 3127 C CD . LYS C 1 50 ? 70.233 58.345 -18.886 1.00 64.00 ? 51 LYS C CD 1 ATOM 3128 C CE . LYS C 1 50 ? 69.976 58.925 -20.273 1.00 80.84 ? 51 LYS C CE 1 ATOM 3129 N NZ . LYS C 1 50 ? 70.355 60.360 -20.372 1.00 91.84 ? 51 LYS C NZ 1 ATOM 3130 N N . HIS C 1 51 ? 70.977 53.475 -16.295 1.00 27.06 ? 52 HIS C N 1 ATOM 3131 C CA . HIS C 1 51 ? 71.521 52.713 -15.156 1.00 26.23 ? 52 HIS C CA 1 ATOM 3132 C C . HIS C 1 51 ? 72.940 53.164 -14.847 1.00 34.40 ? 52 HIS C C 1 ATOM 3133 O O . HIS C 1 51 ? 73.586 53.799 -15.682 1.00 33.20 ? 52 HIS C O 1 ATOM 3134 C CB . HIS C 1 51 ? 71.481 51.202 -15.470 1.00 25.22 ? 52 HIS C CB 1 ATOM 3135 C CG . HIS C 1 51 ? 70.155 50.725 -15.987 1.00 27.76 ? 52 HIS C CG 1 ATOM 3136 N ND1 . HIS C 1 51 ? 69.043 50.611 -15.149 1.00 28.51 ? 52 HIS C ND1 1 ATOM 3137 C CD2 . HIS C 1 51 ? 69.785 50.416 -17.251 1.00 29.35 ? 52 HIS C CD2 1 ATOM 3138 C CE1 . HIS C 1 51 ? 68.058 50.176 -15.914 1.00 28.07 ? 52 HIS C CE1 1 ATOM 3139 N NE2 . HIS C 1 51 ? 68.448 50.063 -17.192 1.00 29.10 ? 52 HIS C NE2 1 ATOM 3140 N N . ARG C 1 52 ? 73.426 52.858 -13.650 1.00 36.14 ? 53 ARG C N 1 ATOM 3141 C CA . ARG C 1 52 ? 74.772 53.247 -13.257 1.00 37.43 ? 53 ARG C CA 1 ATOM 3142 C C . ARG C 1 52 ? 75.798 52.498 -14.126 1.00 41.23 ? 53 ARG C C 1 ATOM 3143 O O . ARG C 1 52 ? 76.734 53.117 -14.628 1.00 40.58 ? 53 ARG C O 1 ATOM 3144 C CB . ARG C 1 52 ? 74.990 52.988 -11.760 1.00 39.51 ? 53 ARG C CB 1 ATOM 3145 C CG . ARG C 1 52 ? 75.999 53.935 -11.137 1.00 60.31 ? 53 ARG C CG 1 ATOM 3146 C CD . ARG C 1 52 ? 76.235 53.645 -9.649 1.00 86.68 ? 53 ARG C CD 1 ATOM 3147 N NE . ARG C 1 52 ? 77.636 53.392 -9.268 1.00 101.94 ? 53 ARG C NE 1 ATOM 3148 C CZ . ARG C 1 52 ? 78.512 54.307 -8.857 1.00 115.18 ? 53 ARG C CZ 1 ATOM 3149 N NH1 . ARG C 1 52 ? 78.153 55.584 -8.755 1.00 95.39 ? 53 ARG C NH1 1 ATOM 3150 N NH2 . ARG C 1 52 ? 79.752 53.952 -8.540 1.00 103.97 ? 53 ARG C NH2 1 ATOM 3151 N N . HIS C 1 53 ? 75.580 51.200 -14.354 1.00 39.06 ? 54 HIS C N 1 ATOM 3152 C CA . HIS C 1 53 ? 76.488 50.386 -15.160 1.00 41.01 ? 54 HIS C CA 1 ATOM 3153 C C . HIS C 1 53 ? 75.914 49.822 -16.452 1.00 44.04 ? 54 HIS C C 1 ATOM 3154 O O . HIS C 1 53 ? 76.557 49.935 -17.501 1.00 48.12 ? 54 HIS C O 1 ATOM 3155 C CB . HIS C 1 53 ? 77.144 49.311 -14.300 1.00 43.43 ? 54 HIS C CB 1 ATOM 3156 C CG . HIS C 1 53 ? 77.879 49.922 -13.136 1.00 47.83 ? 54 HIS C CG 1 ATOM 3157 N ND1 . HIS C 1 53 ? 78.914 50.850 -13.330 1.00 49.69 ? 54 HIS C ND1 1 ATOM 3158 C CD2 . HIS C 1 53 ? 77.641 49.807 -11.807 1.00 49.91 ? 54 HIS C CD2 1 ATOM 3159 C CE1 . HIS C 1 53 ? 79.274 51.239 -12.116 1.00 49.36 ? 54 HIS C CE1 1 ATOM 3160 N NE2 . HIS C 1 53 ? 78.546 50.639 -11.167 1.00 49.84 ? 54 HIS C NE2 1 ATOM 3161 N N . LEU C 1 54 ? 74.691 49.303 -16.401 1.00 34.75 ? 55 LEU C N 1 ATOM 3162 C CA . LEU C 1 54 ? 74.024 48.728 -17.564 1.00 32.15 ? 55 LEU C CA 1 ATOM 3163 C C . LEU C 1 54 ? 73.741 49.708 -18.704 1.00 33.80 ? 55 LEU C C 1 ATOM 3164 O O . LEU C 1 54 ? 73.573 50.902 -18.464 1.00 33.05 ? 55 LEU C O 1 ATOM 3165 C CB . LEU C 1 54 ? 72.754 47.986 -17.138 1.00 31.19 ? 55 LEU C CB 1 ATOM 3166 C CG . LEU C 1 54 ? 72.951 46.768 -16.240 1.00 33.98 ? 55 LEU C CG 1 ATOM 3167 C CD1 . LEU C 1 54 ? 71.636 46.260 -15.795 1.00 34.04 ? 55 LEU C CD1 1 ATOM 3168 C CD2 . LEU C 1 54 ? 73.644 45.639 -16.964 1.00 36.29 ? 55 LEU C CD2 1 ATOM 3169 N N . PRO C 1 55 ? 73.721 49.246 -19.976 1.00 29.19 ? 56 PRO C N 1 ATOM 3170 C CA . PRO C 1 55 ? 73.410 50.185 -21.058 1.00 26.95 ? 56 PRO C CA 1 ATOM 3171 C C . PRO C 1 55 ? 71.958 50.658 -20.979 1.00 31.16 ? 56 PRO C C 1 ATOM 3172 O O . PRO C 1 55 ? 71.050 49.948 -20.529 1.00 28.54 ? 56 PRO C O 1 ATOM 3173 C CB . PRO C 1 55 ? 73.648 49.353 -22.337 1.00 27.33 ? 56 PRO C CB 1 ATOM 3174 C CG . PRO C 1 55 ? 73.559 47.953 -21.933 1.00 30.50 ? 56 PRO C CG 1 ATOM 3175 C CD . PRO C 1 55 ? 73.921 47.865 -20.493 1.00 28.03 ? 56 PRO C CD 1 ATOM 3176 N N . SER C 1 56 ? 71.774 51.886 -21.459 1.00 28.39 ? 57 SER C N 1 ATOM 3177 C CA A SER C 1 56 ? 70.503 52.586 -21.538 0.70 27.03 ? 57 SER C CA 1 ATOM 3178 C CA B SER C 1 56 ? 70.488 52.567 -21.528 0.30 27.19 ? 57 SER C CA 1 ATOM 3179 C C . SER C 1 56 ? 69.578 51.926 -22.581 1.00 31.48 ? 57 SER C C 1 ATOM 3180 O O . SER C 1 56 ? 70.060 51.327 -23.535 1.00 31.28 ? 57 SER C O 1 ATOM 3181 C CB A SER C 1 56 ? 70.771 54.042 -21.916 0.70 27.66 ? 57 SER C CB 1 ATOM 3182 C CB B SER C 1 56 ? 70.703 54.043 -21.859 0.30 28.16 ? 57 SER C CB 1 ATOM 3183 O OG A SER C 1 56 ? 69.566 54.742 -22.165 0.70 34.74 ? 57 SER C OG 1 ATOM 3184 O OG B SER C 1 56 ? 71.528 54.670 -20.892 0.30 30.54 ? 57 SER C OG 1 ATOM 3185 N N . CYS C 1 57 ? 68.260 52.062 -22.421 1.00 28.51 ? 58 CYS C N 1 ATOM 3186 C CA . CYS C 1 57 ? 67.270 51.564 -23.380 1.00 28.20 ? 58 CYS C CA 1 ATOM 3187 C C . CYS C 1 57 ? 66.016 52.480 -23.432 1.00 29.28 ? 58 CYS C C 1 ATOM 3188 O O . CYS C 1 57 ? 65.872 53.361 -22.606 1.00 29.56 ? 58 CYS C O 1 ATOM 3189 C CB . CYS C 1 57 ? 66.936 50.087 -23.198 1.00 30.08 ? 58 CYS C CB 1 ATOM 3190 S SG . CYS C 1 57 ? 65.867 49.711 -21.797 1.00 35.93 ? 58 CYS C SG 1 ATOM 3191 N N . THR C 1 58 ? 65.156 52.304 -24.413 1.00 26.96 ? 59 THR C N 1 ATOM 3192 C CA . THR C 1 58 ? 63.995 53.174 -24.662 1.00 27.56 ? 59 THR C CA 1 ATOM 3193 C C . THR C 1 58 ? 62.779 52.385 -25.116 1.00 32.32 ? 59 THR C C 1 ATOM 3194 O O . THR C 1 58 ? 62.928 51.403 -25.835 1.00 32.81 ? 59 THR C O 1 ATOM 3195 C CB . THR C 1 58 ? 64.431 54.176 -25.787 1.00 42.18 ? 59 THR C CB 1 ATOM 3196 O OG1 . THR C 1 58 ? 65.493 55.011 -25.316 1.00 45.96 ? 59 THR C OG1 1 ATOM 3197 C CG2 . THR C 1 58 ? 63.333 55.055 -26.269 1.00 41.92 ? 59 THR C CG2 1 ATOM 3198 N N . ILE C 1 59 ? 61.593 52.810 -24.698 1.00 30.33 ? 60 ILE C N 1 ATOM 3199 C CA . ILE C 1 59 ? 60.284 52.325 -25.161 1.00 31.90 ? 60 ILE C CA 1 ATOM 3200 C C . ILE C 1 59 ? 59.551 53.599 -25.593 1.00 36.63 ? 60 ILE C C 1 ATOM 3201 O O . ILE C 1 59 ? 59.575 54.581 -24.868 1.00 36.23 ? 60 ILE C O 1 ATOM 3202 C CB . ILE C 1 59 ? 59.455 51.366 -24.234 1.00 35.99 ? 60 ILE C CB 1 ATOM 3203 C CG1 . ILE C 1 59 ? 58.970 52.042 -22.946 1.00 37.54 ? 60 ILE C CG1 1 ATOM 3204 C CG2 . ILE C 1 59 ? 60.226 50.091 -23.917 1.00 38.73 ? 60 ILE C CG2 1 ATOM 3205 C CD1 . ILE C 1 59 ? 57.871 51.269 -22.140 1.00 52.40 ? 60 ILE C CD1 1 ATOM 3206 N N . ALA C 1 60 ? 59.037 53.633 -26.820 1.00 35.11 ? 61 ALA C N 1 ATOM 3207 C CA . ALA C 1 60 ? 58.361 54.797 -27.394 1.00 34.56 ? 61 ALA C CA 1 ATOM 3208 C C . ALA C 1 60 ? 57.056 54.408 -28.029 1.00 39.72 ? 61 ALA C C 1 ATOM 3209 O O . ALA C 1 60 ? 56.933 53.300 -28.554 1.00 40.07 ? 61 ALA C O 1 ATOM 3210 C CB . ALA C 1 60 ? 59.260 55.492 -28.412 1.00 34.92 ? 61 ALA C CB 1 ATOM 3211 N N . TYR C 1 61 ? 56.073 55.307 -27.968 1.00 37.31 ? 62 TYR C N 1 ATOM 3212 C CA . TYR C 1 61 ? 54.770 55.082 -28.575 1.00 38.12 ? 62 TYR C CA 1 ATOM 3213 C C . TYR C 1 61 ? 54.328 56.324 -29.294 1.00 43.65 ? 62 TYR C C 1 ATOM 3214 O O . TYR C 1 61 ? 54.298 57.415 -28.702 1.00 41.67 ? 62 TYR C O 1 ATOM 3215 C CB . TYR C 1 61 ? 53.720 54.661 -27.550 1.00 39.99 ? 62 TYR C CB 1 ATOM 3216 C CG . TYR C 1 61 ? 52.520 53.973 -28.177 1.00 44.69 ? 62 TYR C CG 1 ATOM 3217 C CD1 . TYR C 1 61 ? 51.469 54.711 -28.723 1.00 45.68 ? 62 TYR C CD1 1 ATOM 3218 C CD2 . TYR C 1 61 ? 52.415 52.587 -28.193 1.00 46.80 ? 62 TYR C CD2 1 ATOM 3219 C CE1 . TYR C 1 61 ? 50.386 54.083 -29.345 1.00 46.63 ? 62 TYR C CE1 1 ATOM 3220 C CE2 . TYR C 1 61 ? 51.322 51.950 -28.789 1.00 47.12 ? 62 TYR C CE2 1 ATOM 3221 C CZ . TYR C 1 61 ? 50.319 52.702 -29.381 1.00 55.88 ? 62 TYR C CZ 1 ATOM 3222 O OH . TYR C 1 61 ? 49.239 52.082 -29.978 1.00 58.92 ? 62 TYR C OH 1 ATOM 3223 N N . ASN C 1 62 ? 54.054 56.177 -30.589 1.00 42.31 ? 63 ASN C N 1 ATOM 3224 C CA . ASN C 1 62 ? 53.520 57.269 -31.392 1.00 43.36 ? 63 ASN C CA 1 ATOM 3225 C C . ASN C 1 62 ? 51.990 57.106 -31.360 1.00 47.96 ? 63 ASN C C 1 ATOM 3226 O O . ASN C 1 62 ? 51.476 56.154 -31.945 1.00 45.87 ? 63 ASN C O 1 ATOM 3227 C CB . ASN C 1 62 ? 54.036 57.205 -32.821 1.00 45.35 ? 63 ASN C CB 1 ATOM 3228 C CG . ASN C 1 62 ? 53.732 58.462 -33.574 1.00 55.47 ? 63 ASN C CG 1 ATOM 3229 O OD1 . ASN C 1 62 ? 52.584 58.958 -33.588 1.00 43.55 ? 63 ASN C OD1 1 ATOM 3230 N ND2 . ASN C 1 62 ? 54.789 59.051 -34.125 1.00 39.58 ? 63 ASN C ND2 1 ATOM 3231 N N . LEU C 1 63 ? 51.283 57.998 -30.625 1.00 46.72 ? 64 LEU C N 1 ATOM 3232 C CA . LEU C 1 63 ? 49.821 57.949 -30.451 1.00 47.23 ? 64 LEU C CA 1 ATOM 3233 C C . LEU C 1 63 ? 49.061 58.382 -31.711 1.00 56.75 ? 64 LEU C C 1 ATOM 3234 O O . LEU C 1 63 ? 47.944 57.914 -31.959 1.00 55.94 ? 64 LEU C O 1 ATOM 3235 C CB . LEU C 1 63 ? 49.389 58.778 -29.229 1.00 47.01 ? 64 LEU C CB 1 ATOM 3236 C CG . LEU C 1 63 ? 49.657 58.168 -27.851 1.00 49.97 ? 64 LEU C CG 1 ATOM 3237 C CD1 . LEU C 1 63 ? 51.063 58.478 -27.389 1.00 49.48 ? 64 LEU C CD1 1 ATOM 3238 C CD2 . LEU C 1 63 ? 48.688 58.694 -26.836 1.00 49.97 ? 64 LEU C CD2 1 ATOM 3239 N N . ASP C 1 64 ? 49.698 59.242 -32.517 1.00 58.22 ? 65 ASP C N 1 ATOM 3240 C CA . ASP C 1 64 ? 49.151 59.718 -33.764 1.00 60.12 ? 65 ASP C CA 1 ATOM 3241 C C . ASP C 1 64 ? 49.134 58.571 -34.790 1.00 63.46 ? 65 ASP C C 1 ATOM 3242 O O . ASP C 1 64 ? 48.057 58.197 -35.265 1.00 63.55 ? 65 ASP C O 1 ATOM 3243 C CB . ASP C 1 64 ? 49.990 60.899 -34.268 1.00 64.02 ? 65 ASP C CB 1 ATOM 3244 C CG . ASP C 1 64 ? 49.396 61.669 -35.421 1.00 92.83 ? 65 ASP C CG 1 ATOM 3245 O OD1 . ASP C 1 64 ? 48.165 61.532 -35.666 1.00 96.30 ? 65 ASP C OD1 1 ATOM 3246 O OD2 . ASP C 1 64 ? 50.148 62.439 -36.068 1.00 104.01 ? 65 ASP C OD2 1 ATOM 3247 N N . LYS C 1 65 ? 50.322 57.984 -35.086 1.00 58.10 ? 66 LYS C N 1 ATOM 3248 C CA . LYS C 1 65 ? 50.517 56.908 -36.070 1.00 55.51 ? 66 LYS C CA 1 ATOM 3249 C C . LYS C 1 65 ? 50.238 55.506 -35.538 1.00 57.79 ? 66 LYS C C 1 ATOM 3250 O O . LYS C 1 65 ? 50.365 54.550 -36.298 1.00 58.57 ? 66 LYS C O 1 ATOM 3251 C CB . LYS C 1 65 ? 51.926 56.980 -36.692 1.00 56.04 ? 66 LYS C CB 1 ATOM 3252 C CG . LYS C 1 65 ? 52.356 58.367 -37.191 1.00 72.68 ? 66 LYS C CG 1 ATOM 3253 C CD . LYS C 1 65 ? 51.473 58.967 -38.307 1.00 84.07 ? 66 LYS C CD 1 ATOM 3254 C CE . LYS C 1 65 ? 51.714 60.445 -38.454 1.00 95.36 ? 66 LYS C CE 1 ATOM 3255 N NZ . LYS C 1 65 ? 50.699 61.080 -39.330 1.00 106.18 ? 66 LYS C NZ 1 ATOM 3256 N N . LYS C 1 66 ? 49.863 55.379 -34.244 1.00 52.68 ? 67 LYS C N 1 ATOM 3257 C CA . LYS C 1 66 ? 49.583 54.109 -33.547 1.00 51.94 ? 67 LYS C CA 1 ATOM 3258 C C . LYS C 1 66 ? 50.727 53.061 -33.630 1.00 52.92 ? 67 LYS C C 1 ATOM 3259 O O . LYS C 1 66 ? 50.492 51.852 -33.628 1.00 51.99 ? 67 LYS C O 1 ATOM 3260 C CB . LYS C 1 66 ? 48.190 53.552 -33.919 1.00 55.53 ? 67 LYS C CB 1 ATOM 3261 C CG . LYS C 1 66 ? 47.029 54.381 -33.362 1.00 73.84 ? 67 LYS C CG 1 ATOM 3262 C CD . LYS C 1 66 ? 45.701 53.651 -33.491 1.00 90.17 ? 67 LYS C CD 1 ATOM 3263 C CE . LYS C 1 66 ? 44.636 54.267 -32.610 1.00 114.42 ? 67 LYS C CE 1 ATOM 3264 N NZ . LYS C 1 66 ? 43.412 53.416 -32.554 1.00 128.15 ? 67 LYS C NZ 1 ATOM 3265 N N . THR C 1 67 ? 51.971 53.543 -33.675 1.00 48.36 ? 68 THR C N 1 ATOM 3266 C CA . THR C 1 67 ? 53.156 52.699 -33.768 1.00 47.86 ? 68 THR C CA 1 ATOM 3267 C C . THR C 1 67 ? 53.994 52.721 -32.491 1.00 51.47 ? 68 THR C C 1 ATOM 3268 O O . THR C 1 67 ? 53.911 53.663 -31.699 1.00 51.45 ? 68 THR C O 1 ATOM 3269 C CB . THR C 1 67 ? 54.002 53.090 -34.997 1.00 55.86 ? 68 THR C CB 1 ATOM 3270 O OG1 . THR C 1 67 ? 54.438 54.443 -34.885 1.00 52.27 ? 68 THR C OG1 1 ATOM 3271 C CG2 . THR C 1 67 ? 53.268 52.895 -36.295 1.00 56.74 ? 68 THR C CG2 1 ATOM 3272 N N . ASN C 1 68 ? 54.837 51.702 -32.320 1.00 47.34 ? 69 ASN C N 1 ATOM 3273 C CA . ASN C 1 68 ? 55.705 51.653 -31.154 1.00 47.06 ? 69 ASN C CA 1 ATOM 3274 C C . ASN C 1 68 ? 57.060 51.043 -31.457 1.00 44.98 ? 69 ASN C C 1 ATOM 3275 O O . ASN C 1 68 ? 57.154 50.247 -32.374 1.00 44.23 ? 69 ASN C O 1 ATOM 3276 C CB . ASN C 1 68 ? 54.993 51.028 -29.928 1.00 50.06 ? 69 ASN C CB 1 ATOM 3277 C CG . ASN C 1 68 ? 54.965 49.545 -29.875 1.00 69.33 ? 69 ASN C CG 1 ATOM 3278 O OD1 . ASN C 1 68 ? 55.948 48.891 -29.517 1.00 72.84 ? 69 ASN C OD1 1 ATOM 3279 N ND2 . ASN C 1 68 ? 53.834 48.994 -30.173 1.00 69.19 ? 69 ASN C ND2 1 ATOM 3280 N N . GLU C 1 69 ? 58.101 51.482 -30.738 1.00 38.06 ? 70 GLU C N 1 ATOM 3281 C CA . GLU C 1 69 ? 59.483 51.017 -30.820 1.00 37.40 ? 70 GLU C CA 1 ATOM 3282 C C . GLU C 1 69 ? 59.934 50.613 -29.401 1.00 40.18 ? 70 GLU C C 1 ATOM 3283 O O . GLU C 1 69 ? 59.431 51.140 -28.400 1.00 38.88 ? 70 GLU C O 1 ATOM 3284 C CB . GLU C 1 69 ? 60.422 52.136 -31.261 1.00 39.15 ? 70 GLU C CB 1 ATOM 3285 C CG . GLU C 1 69 ? 60.269 52.694 -32.653 1.00 54.42 ? 70 GLU C CG 1 ATOM 3286 C CD . GLU C 1 69 ? 61.054 53.977 -32.885 1.00 90.86 ? 70 GLU C CD 1 ATOM 3287 O OE1 . GLU C 1 69 ? 62.010 54.256 -32.121 1.00 84.03 ? 70 GLU C OE1 1 ATOM 3288 O OE2 . GLU C 1 69 ? 60.716 54.703 -33.850 1.00 96.25 ? 70 GLU C OE2 1 ATOM 3289 N N . THR C 1 70 ? 60.909 49.712 -29.327 1.00 35.26 ? 71 THR C N 1 ATOM 3290 C CA . THR C 1 70 ? 61.504 49.264 -28.072 1.00 33.91 ? 71 THR C CA 1 ATOM 3291 C C . THR C 1 70 ? 62.915 48.794 -28.284 1.00 34.47 ? 71 THR C C 1 ATOM 3292 O O . THR C 1 70 ? 63.181 48.083 -29.239 1.00 34.16 ? 71 THR C O 1 ATOM 3293 C CB . THR C 1 70 ? 60.630 48.219 -27.302 1.00 36.98 ? 71 THR C CB 1 ATOM 3294 O OG1 . THR C 1 70 ? 61.336 47.810 -26.133 1.00 30.06 ? 71 THR C OG1 1 ATOM 3295 C CG2 . THR C 1 70 ? 60.273 46.985 -28.124 1.00 30.05 ? 71 THR C CG2 1 ATOM 3296 N N . SER C 1 71 ? 63.815 49.207 -27.404 1.00 29.40 ? 72 SER C N 1 ATOM 3297 C CA . SER C 1 71 ? 65.172 48.688 -27.345 1.00 28.66 ? 72 SER C CA 1 ATOM 3298 C C . SER C 1 71 ? 65.362 48.025 -25.946 1.00 31.25 ? 72 SER C C 1 ATOM 3299 O O . SER C 1 71 ? 66.480 47.689 -25.591 1.00 29.46 ? 72 SER C O 1 ATOM 3300 C CB . SER C 1 71 ? 66.221 49.751 -27.663 1.00 30.04 ? 72 SER C CB 1 ATOM 3301 O OG . SER C 1 71 ? 66.306 50.757 -26.672 1.00 40.38 ? 72 SER C OG 1 ATOM 3302 N N . CYS C 1 72 ? 64.268 47.878 -25.143 1.00 27.65 ? 73 CYS C N 1 ATOM 3303 C CA . CYS C 1 72 ? 64.326 47.198 -23.839 1.00 29.65 ? 73 CYS C CA 1 ATOM 3304 C C . CYS C 1 72 ? 63.861 45.806 -24.123 1.00 31.27 ? 73 CYS C C 1 ATOM 3305 O O . CYS C 1 72 ? 62.649 45.510 -24.039 1.00 29.58 ? 73 CYS C O 1 ATOM 3306 C CB . CYS C 1 72 ? 63.457 47.863 -22.770 1.00 31.70 ? 73 CYS C CB 1 ATOM 3307 S SG . CYS C 1 72 ? 63.896 49.574 -22.424 1.00 36.98 ? 73 CYS C SG 1 ATOM 3308 N N . LEU C 1 73 ? 64.827 44.961 -24.520 1.00 25.83 ? 74 LEU C N 1 ATOM 3309 C CA . LEU C 1 73 ? 64.543 43.593 -24.928 1.00 24.38 ? 74 LEU C CA 1 ATOM 3310 C C . LEU C 1 73 ? 65.000 42.563 -23.927 1.00 27.83 ? 74 LEU C C 1 ATOM 3311 O O . LEU C 1 73 ? 66.118 42.608 -23.471 1.00 28.35 ? 74 LEU C O 1 ATOM 3312 C CB . LEU C 1 73 ? 65.087 43.330 -26.330 1.00 23.83 ? 74 LEU C CB 1 ATOM 3313 C CG . LEU C 1 73 ? 64.743 44.399 -27.392 1.00 27.36 ? 74 LEU C CG 1 ATOM 3314 C CD1 . LEU C 1 73 ? 65.708 44.355 -28.512 1.00 25.57 ? 74 LEU C CD1 1 ATOM 3315 C CD2 . LEU C 1 73 ? 63.301 44.265 -27.896 1.00 27.69 ? 74 LEU C CD2 1 ATOM 3316 N N . GLY C 1 74 ? 64.109 41.667 -23.550 1.00 26.45 ? 75 GLY C N 1 ATOM 3317 C CA . GLY C 1 74 ? 64.418 40.644 -22.560 1.00 27.16 ? 75 GLY C CA 1 ATOM 3318 C C . GLY C 1 74 ? 64.726 41.235 -21.193 1.00 30.54 ? 75 GLY C C 1 ATOM 3319 O O . GLY C 1 74 ? 65.466 40.642 -20.412 1.00 29.86 ? 75 GLY C O 1 ATOM 3320 N N . ARG C 1 75 ? 64.196 42.436 -20.910 1.00 25.70 ? 76 ARG C N 1 ATOM 3321 C CA . ARG C 1 75 ? 64.446 43.118 -19.639 1.00 24.48 ? 76 ARG C CA 1 ATOM 3322 C C . ARG C 1 75 ? 63.178 43.222 -18.818 1.00 27.24 ? 76 ARG C C 1 ATOM 3323 O O . ARG C 1 75 ? 63.212 43.840 -17.771 1.00 25.33 ? 76 ARG C O 1 ATOM 3324 C CB . ARG C 1 75 ? 65.041 44.511 -19.848 1.00 18.20 ? 76 ARG C CB 1 ATOM 3325 C CG . ARG C 1 75 ? 66.350 44.516 -20.599 1.00 18.71 ? 76 ARG C CG 1 ATOM 3326 C CD . ARG C 1 75 ? 67.071 45.800 -20.313 1.00 24.17 ? 76 ARG C CD 1 ATOM 3327 N NE . ARG C 1 75 ? 67.436 45.835 -18.894 1.00 22.29 ? 76 ARG C NE 1 ATOM 3328 C CZ . ARG C 1 75 ? 67.578 46.942 -18.184 1.00 31.94 ? 76 ARG C CZ 1 ATOM 3329 N NH1 . ARG C 1 75 ? 67.389 48.129 -18.744 1.00 16.70 ? 76 ARG C NH1 1 ATOM 3330 N NH2 . ARG C 1 75 ? 67.860 46.872 -16.894 1.00 24.12 ? 76 ARG C NH2 1 ATOM 3331 N N . ASN C 1 76 ? 62.072 42.609 -19.282 1.00 25.98 ? 77 ASN C N 1 ATOM 3332 C CA . ASN C 1 76 ? 60.769 42.645 -18.597 1.00 27.94 ? 77 ASN C CA 1 ATOM 3333 C C . ASN C 1 76 ? 60.131 44.021 -18.378 1.00 34.81 ? 77 ASN C C 1 ATOM 3334 O O . ASN C 1 76 ? 59.339 44.184 -17.442 1.00 37.01 ? 77 ASN C O 1 ATOM 3335 C CB . ASN C 1 76 ? 60.824 41.840 -17.317 1.00 36.98 ? 77 ASN C CB 1 ATOM 3336 C CG . ASN C 1 76 ? 60.469 40.422 -17.578 1.00 71.72 ? 77 ASN C CG 1 ATOM 3337 O OD1 . ASN C 1 76 ? 59.520 40.124 -18.320 1.00 68.09 ? 77 ASN C OD1 1 ATOM 3338 N ND2 . ASN C 1 76 ? 61.184 39.501 -16.998 1.00 74.06 ? 77 ASN C ND2 1 ATOM 3339 N N . ILE C 1 77 ? 60.463 44.990 -19.271 1.00 30.03 ? 78 ILE C N 1 ATOM 3340 C CA . ILE C 1 77 ? 60.011 46.377 -19.308 1.00 29.47 ? 78 ILE C CA 1 ATOM 3341 C C . ILE C 1 77 ? 59.068 46.530 -20.519 1.00 34.28 ? 78 ILE C C 1 ATOM 3342 O O . ILE C 1 77 ? 59.460 46.250 -21.648 1.00 33.39 ? 78 ILE C O 1 ATOM 3343 C CB . ILE C 1 77 ? 61.218 47.353 -19.422 1.00 31.59 ? 78 ILE C CB 1 ATOM 3344 C CG1 . ILE C 1 77 ? 62.215 47.182 -18.267 1.00 28.91 ? 78 ILE C CG1 1 ATOM 3345 C CG2 . ILE C 1 77 ? 60.728 48.811 -19.570 1.00 33.24 ? 78 ILE C CG2 1 ATOM 3346 C CD1 . ILE C 1 77 ? 63.485 47.937 -18.450 1.00 25.80 ? 78 ILE C CD1 1 ATOM 3347 N N . THR C 1 78 ? 57.814 46.924 -20.271 1.00 30.64 ? 79 THR C N 1 ATOM 3348 C CA . THR C 1 78 ? 56.781 47.068 -21.308 1.00 30.63 ? 79 THR C CA 1 ATOM 3349 C C . THR C 1 78 ? 55.819 48.196 -20.903 1.00 33.95 ? 79 THR C C 1 ATOM 3350 O O . THR C 1 78 ? 55.874 48.694 -19.773 1.00 33.21 ? 79 THR C O 1 ATOM 3351 C CB . THR C 1 78 ? 55.914 45.745 -21.431 1.00 38.36 ? 79 THR C CB 1 ATOM 3352 O OG1 . THR C 1 78 ? 55.170 45.558 -20.235 1.00 42.69 ? 79 THR C OG1 1 ATOM 3353 C CG2 . THR C 1 78 ? 56.721 44.466 -21.693 1.00 35.47 ? 79 THR C CG2 1 ATOM 3354 N N . TRP C 1 79 ? 54.881 48.531 -21.800 1.00 30.36 ? 80 TRP C N 1 ATOM 3355 C CA . TRP C 1 79 ? 53.763 49.441 -21.558 1.00 29.71 ? 80 TRP C CA 1 ATOM 3356 C C . TRP C 1 79 ? 52.771 48.627 -20.713 1.00 36.22 ? 80 TRP C C 1 ATOM 3357 O O . TRP C 1 79 ? 52.520 47.481 -21.052 1.00 36.83 ? 80 TRP C O 1 ATOM 3358 C CB . TRP C 1 79 ? 53.097 49.828 -22.896 1.00 27.27 ? 80 TRP C CB 1 ATOM 3359 C CG . TRP C 1 79 ? 53.939 50.776 -23.708 1.00 26.86 ? 80 TRP C CG 1 ATOM 3360 C CD1 . TRP C 1 79 ? 54.648 50.490 -24.839 1.00 28.94 ? 80 TRP C CD1 1 ATOM 3361 C CD2 . TRP C 1 79 ? 54.200 52.160 -23.407 1.00 26.19 ? 80 TRP C CD2 1 ATOM 3362 N NE1 . TRP C 1 79 ? 55.316 51.614 -25.275 1.00 26.98 ? 80 TRP C NE1 1 ATOM 3363 C CE2 . TRP C 1 79 ? 55.063 52.651 -24.411 1.00 27.84 ? 80 TRP C CE2 1 ATOM 3364 C CE3 . TRP C 1 79 ? 53.731 53.049 -22.415 1.00 27.60 ? 80 TRP C CE3 1 ATOM 3365 C CZ2 . TRP C 1 79 ? 55.488 53.984 -24.445 1.00 27.10 ? 80 TRP C CZ2 1 ATOM 3366 C CZ3 . TRP C 1 79 ? 54.159 54.372 -22.446 1.00 28.74 ? 80 TRP C CZ3 1 ATOM 3367 C CH2 . TRP C 1 79 ? 55.031 54.824 -23.452 1.00 28.85 ? 80 TRP C CH2 1 ATOM 3368 N N . ALA C 1 80 ? 52.252 49.186 -19.605 1.00 34.04 ? 81 ALA C N 1 ATOM 3369 C CA . ALA C 1 80 ? 51.283 48.501 -18.739 1.00 35.39 ? 81 ALA C CA 1 ATOM 3370 C C . ALA C 1 80 ? 50.065 48.043 -19.561 1.00 44.73 ? 81 ALA C C 1 ATOM 3371 O O . ALA C 1 80 ? 49.585 46.925 -19.389 1.00 47.09 ? 81 ALA C O 1 ATOM 3372 C CB . ALA C 1 80 ? 50.845 49.410 -17.588 1.00 35.50 ? 81 ALA C CB 1 ATOM 3373 N N . SER C 1 81 ? 49.626 48.895 -20.483 1.00 43.50 ? 82 SER C N 1 ATOM 3374 C CA . SER C 1 81 ? 48.563 48.710 -21.480 1.00 43.11 ? 82 SER C CA 1 ATOM 3375 C C . SER C 1 81 ? 48.862 49.711 -22.613 1.00 47.47 ? 82 SER C C 1 ATOM 3376 O O . SER C 1 81 ? 49.775 50.529 -22.473 1.00 46.88 ? 82 SER C O 1 ATOM 3377 C CB . SER C 1 81 ? 47.192 48.971 -20.860 1.00 46.13 ? 82 SER C CB 1 ATOM 3378 O OG . SER C 1 81 ? 47.102 50.280 -20.322 1.00 61.52 ? 82 SER C OG 1 ATOM 3379 N N . THR C 1 82 ? 48.129 49.645 -23.723 1.00 46.95 ? 83 THR C N 1 ATOM 3380 C CA . THR C 1 82 ? 48.327 50.561 -24.850 1.00 46.99 ? 83 THR C CA 1 ATOM 3381 C C . THR C 1 82 ? 48.156 51.988 -24.353 1.00 50.48 ? 83 THR C C 1 ATOM 3382 O O . THR C 1 82 ? 47.119 52.304 -23.755 1.00 50.56 ? 83 THR C O 1 ATOM 3383 C CB . THR C 1 82 ? 47.409 50.207 -26.027 1.00 55.75 ? 83 THR C CB 1 ATOM 3384 O OG1 . THR C 1 82 ? 47.693 48.863 -26.432 1.00 57.23 ? 83 THR C OG1 1 ATOM 3385 C CG2 . THR C 1 82 ? 47.592 51.160 -27.224 1.00 50.98 ? 83 THR C CG2 1 ATOM 3386 N N . PRO C 1 83 ? 49.181 52.851 -24.528 1.00 46.55 ? 84 PRO C N 1 ATOM 3387 C CA . PRO C 1 83 ? 49.069 54.216 -23.990 1.00 47.65 ? 84 PRO C CA 1 ATOM 3388 C C . PRO C 1 83 ? 48.084 55.147 -24.695 1.00 56.05 ? 84 PRO C C 1 ATOM 3389 O O . PRO C 1 83 ? 48.052 55.216 -25.940 1.00 54.69 ? 84 PRO C O 1 ATOM 3390 C CB . PRO C 1 83 ? 50.504 54.737 -24.019 1.00 48.79 ? 84 PRO C CB 1 ATOM 3391 C CG . PRO C 1 83 ? 51.176 53.937 -25.034 1.00 52.00 ? 84 PRO C CG 1 ATOM 3392 C CD . PRO C 1 83 ? 50.489 52.626 -25.171 1.00 46.98 ? 84 PRO C CD 1 ATOM 3393 N N . ASP C 1 84 ? 47.266 55.857 -23.862 1.00 55.57 ? 85 ASP C N 1 ATOM 3394 C CA . ASP C 1 84 ? 46.288 56.860 -24.293 1.00 55.81 ? 85 ASP C CA 1 ATOM 3395 C C . ASP C 1 84 ? 46.259 58.074 -23.329 1.00 57.89 ? 85 ASP C C 1 ATOM 3396 O O . ASP C 1 84 ? 47.014 59.024 -23.541 1.00 55.26 ? 85 ASP C O 1 ATOM 3397 C CB . ASP C 1 84 ? 44.899 56.227 -24.529 1.00 58.19 ? 85 ASP C CB 1 ATOM 3398 C CG . ASP C 1 84 ? 43.838 57.169 -25.092 1.00 71.26 ? 85 ASP C CG 1 ATOM 3399 O OD1 . ASP C 1 84 ? 44.216 58.169 -25.770 1.00 70.06 ? 85 ASP C OD1 1 ATOM 3400 O OD2 . ASP C 1 84 ? 42.627 56.908 -24.861 1.00 78.87 ? 85 ASP C OD2 1 ATOM 3401 N N . HIS C 1 85 ? 45.425 58.028 -22.265 1.00 55.18 ? 86 HIS C N 1 ATOM 3402 C CA . HIS C 1 85 ? 45.292 59.111 -21.271 1.00 55.51 ? 86 HIS C CA 1 ATOM 3403 C C . HIS C 1 85 ? 46.049 58.830 -19.953 1.00 53.73 ? 86 HIS C C 1 ATOM 3404 O O . HIS C 1 85 ? 46.247 59.743 -19.147 1.00 51.82 ? 86 HIS C O 1 ATOM 3405 C CB . HIS C 1 85 ? 43.808 59.417 -20.997 1.00 58.06 ? 86 HIS C CB 1 ATOM 3406 C CG . HIS C 1 85 ? 43.064 59.884 -22.209 1.00 63.23 ? 86 HIS C CG 1 ATOM 3407 N ND1 . HIS C 1 85 ? 43.608 60.829 -23.073 1.00 65.73 ? 86 HIS C ND1 1 ATOM 3408 C CD2 . HIS C 1 85 ? 41.838 59.531 -22.666 1.00 66.28 ? 86 HIS C CD2 1 ATOM 3409 C CE1 . HIS C 1 85 ? 42.708 61.009 -24.026 1.00 65.63 ? 86 HIS C CE1 1 ATOM 3410 N NE2 . HIS C 1 85 ? 41.623 60.259 -23.824 1.00 66.27 ? 86 HIS C NE2 1 ATOM 3411 N N . SER C 1 86 ? 46.465 57.560 -19.756 1.00 46.39 ? 87 SER C N 1 ATOM 3412 C CA . SER C 1 86 ? 47.231 57.090 -18.606 1.00 43.97 ? 87 SER C CA 1 ATOM 3413 C C . SER C 1 86 ? 48.490 56.276 -19.057 1.00 45.20 ? 87 SER C C 1 ATOM 3414 O O . SER C 1 86 ? 48.560 55.082 -18.726 1.00 42.70 ? 87 SER C O 1 ATOM 3415 C CB . SER C 1 86 ? 46.343 56.245 -17.707 1.00 42.81 ? 87 SER C CB 1 ATOM 3416 O OG . SER C 1 86 ? 45.376 57.051 -17.071 1.00 49.36 ? 87 SER C OG 1 ATOM 3417 N N . PRO C 1 87 ? 49.473 56.876 -19.814 1.00 40.05 ? 88 PRO C N 1 ATOM 3418 C CA . PRO C 1 87 ? 50.673 56.111 -20.213 1.00 39.02 ? 88 PRO C CA 1 ATOM 3419 C C . PRO C 1 87 ? 51.453 55.675 -18.974 1.00 40.69 ? 88 PRO C C 1 ATOM 3420 O O . PRO C 1 87 ? 51.698 56.471 -18.055 1.00 39.58 ? 88 PRO C O 1 ATOM 3421 C CB . PRO C 1 87 ? 51.462 57.089 -21.074 1.00 40.95 ? 88 PRO C CB 1 ATOM 3422 C CG . PRO C 1 87 ? 50.998 58.408 -20.656 1.00 46.19 ? 88 PRO C CG 1 ATOM 3423 C CD . PRO C 1 87 ? 49.557 58.262 -20.300 1.00 41.57 ? 88 PRO C CD 1 ATOM 3424 N N . GLU C 1 88 ? 51.752 54.371 -18.922 1.00 34.62 ? 89 GLU C N 1 ATOM 3425 C CA . GLU C 1 88 ? 52.353 53.729 -17.782 1.00 32.51 ? 89 GLU C CA 1 ATOM 3426 C C . GLU C 1 88 ? 53.335 52.643 -18.194 1.00 34.97 ? 89 GLU C C 1 ATOM 3427 O O . GLU C 1 88 ? 53.005 51.767 -19.000 1.00 33.47 ? 89 GLU C O 1 ATOM 3428 C CB . GLU C 1 88 ? 51.221 53.143 -16.925 1.00 33.05 ? 89 GLU C CB 1 ATOM 3429 C CG . GLU C 1 88 ? 51.560 52.855 -15.482 1.00 36.56 ? 89 GLU C CG 1 ATOM 3430 C CD . GLU C 1 88 ? 50.368 52.460 -14.623 1.00 54.19 ? 89 GLU C CD 1 ATOM 3431 O OE1 . GLU C 1 88 ? 49.447 51.772 -15.126 1.00 46.13 ? 89 GLU C OE1 1 ATOM 3432 O OE2 . GLU C 1 88 ? 50.359 52.841 -13.432 1.00 52.49 ? 89 GLU C OE2 1 ATOM 3433 N N . LEU C 1 89 ? 54.548 52.708 -17.627 1.00 30.79 ? 90 LEU C N 1 ATOM 3434 C CA . LEU C 1 89 ? 55.583 51.710 -17.840 1.00 29.10 ? 90 LEU C CA 1 ATOM 3435 C C . LEU C 1 89 ? 55.369 50.645 -16.751 1.00 32.64 ? 90 LEU C C 1 ATOM 3436 O O . LEU C 1 89 ? 55.058 50.964 -15.604 1.00 30.54 ? 90 LEU C O 1 ATOM 3437 C CB . LEU C 1 89 ? 56.975 52.344 -17.708 1.00 28.16 ? 90 LEU C CB 1 ATOM 3438 C CG . LEU C 1 89 ? 58.203 51.446 -17.988 1.00 31.75 ? 90 LEU C CG 1 ATOM 3439 C CD1 . LEU C 1 89 ? 59.274 52.192 -18.715 1.00 30.17 ? 90 LEU C CD1 1 ATOM 3440 C CD2 . LEU C 1 89 ? 58.805 50.936 -16.701 1.00 37.33 ? 90 LEU C CD2 1 ATOM 3441 N N . GLN C 1 90 ? 55.555 49.382 -17.134 1.00 29.51 ? 91 GLN C N 1 ATOM 3442 C CA . GLN C 1 90 ? 55.456 48.243 -16.251 1.00 28.59 ? 91 GLN C CA 1 ATOM 3443 C C . GLN C 1 90 ? 56.760 47.434 -16.254 1.00 32.14 ? 91 GLN C C 1 ATOM 3444 O O . GLN C 1 90 ? 57.299 47.123 -17.316 1.00 30.76 ? 91 GLN C O 1 ATOM 3445 C CB . GLN C 1 90 ? 54.323 47.334 -16.726 1.00 29.04 ? 91 GLN C CB 1 ATOM 3446 C CG . GLN C 1 90 ? 53.976 46.230 -15.752 1.00 36.72 ? 91 GLN C CG 1 ATOM 3447 C CD . GLN C 1 90 ? 52.974 45.290 -16.361 1.00 57.10 ? 91 GLN C CD 1 ATOM 3448 O OE1 . GLN C 1 90 ? 53.332 44.368 -17.093 1.00 48.30 ? 91 GLN C OE1 1 ATOM 3449 N NE2 . GLN C 1 90 ? 51.685 45.570 -16.160 1.00 55.40 ? 91 GLN C NE2 1 ATOM 3450 N N . ILE C 1 91 ? 57.224 47.042 -15.060 1.00 28.83 ? 92 ILE C N 1 ATOM 3451 C CA . ILE C 1 91 ? 58.327 46.085 -14.877 1.00 27.87 ? 92 ILE C CA 1 ATOM 3452 C C . ILE C 1 91 ? 57.615 44.933 -14.152 1.00 31.64 ? 92 ILE C C 1 ATOM 3453 O O . ILE C 1 91 ? 57.210 45.091 -13.011 1.00 31.34 ? 92 ILE C O 1 ATOM 3454 C CB . ILE C 1 91 ? 59.565 46.624 -14.097 1.00 29.87 ? 92 ILE C CB 1 ATOM 3455 C CG1 . ILE C 1 91 ? 60.099 47.955 -14.679 1.00 27.81 ? 92 ILE C CG1 1 ATOM 3456 C CG2 . ILE C 1 91 ? 60.640 45.573 -14.059 1.00 29.92 ? 92 ILE C CG2 1 ATOM 3457 C CD1 . ILE C 1 91 ? 60.950 48.731 -13.730 1.00 25.84 ? 92 ILE C CD1 1 ATOM 3458 N N . SER C 1 92 ? 57.318 43.856 -14.867 1.00 29.33 ? 93 SER C N 1 ATOM 3459 C CA . SER C 1 92 ? 56.570 42.726 -14.331 1.00 29.81 ? 93 SER C CA 1 ATOM 3460 C C . SER C 1 92 ? 57.122 42.058 -13.035 1.00 36.96 ? 93 SER C C 1 ATOM 3461 O O . SER C 1 92 ? 56.333 41.626 -12.183 1.00 40.25 ? 93 SER C O 1 ATOM 3462 C CB . SER C 1 92 ? 56.345 41.702 -15.431 1.00 32.97 ? 93 SER C CB 1 ATOM 3463 O OG . SER C 1 92 ? 57.598 41.202 -15.863 1.00 41.33 ? 93 SER C OG 1 ATOM 3464 N N . ALA C 1 93 ? 58.452 41.931 -12.911 1.00 31.39 ? 94 ALA C N 1 ATOM 3465 C CA . ALA C 1 93 ? 59.138 41.365 -11.742 1.00 29.82 ? 94 ALA C CA 1 ATOM 3466 C C . ALA C 1 93 ? 60.436 42.103 -11.645 1.00 34.73 ? 94 ALA C C 1 ATOM 3467 O O . ALA C 1 93 ? 61.349 41.870 -12.446 1.00 37.68 ? 94 ALA C O 1 ATOM 3468 C CB . ALA C 1 93 ? 59.421 39.887 -11.948 1.00 29.86 ? 94 ALA C CB 1 ATOM 3469 N N . VAL C 1 94 ? 60.499 43.039 -10.723 1.00 27.29 ? 95 VAL C N 1 ATOM 3470 C CA . VAL C 1 94 ? 61.673 43.847 -10.462 1.00 26.40 ? 95 VAL C CA 1 ATOM 3471 C C . VAL C 1 94 ? 62.887 42.961 -10.049 1.00 32.59 ? 95 VAL C C 1 ATOM 3472 O O . VAL C 1 94 ? 62.739 41.943 -9.358 1.00 31.40 ? 95 VAL C O 1 ATOM 3473 C CB . VAL C 1 94 ? 61.273 44.883 -9.396 1.00 29.89 ? 95 VAL C CB 1 ATOM 3474 C CG1 . VAL C 1 94 ? 62.447 45.375 -8.580 1.00 28.96 ? 95 VAL C CG1 1 ATOM 3475 C CG2 . VAL C 1 94 ? 60.533 46.028 -10.044 1.00 29.79 ? 95 VAL C CG2 1 ATOM 3476 N N . ALA C 1 95 ? 64.073 43.321 -10.562 1.00 28.92 ? 96 ALA C N 1 ATOM 3477 C CA . ALA C 1 95 ? 65.344 42.662 -10.287 1.00 25.88 ? 96 ALA C CA 1 ATOM 3478 C C . ALA C 1 95 ? 66.382 43.782 -10.043 1.00 30.43 ? 96 ALA C C 1 ATOM 3479 O O . ALA C 1 95 ? 66.111 44.946 -10.337 1.00 29.68 ? 96 ALA C O 1 ATOM 3480 C CB . ALA C 1 95 ? 65.744 41.806 -11.486 1.00 25.42 ? 96 ALA C CB 1 ATOM 3481 N N . LEU C 1 96 ? 67.567 43.441 -9.515 1.00 25.75 ? 97 LEU C N 1 ATOM 3482 C CA . LEU C 1 96 ? 68.616 44.427 -9.267 1.00 23.83 ? 97 LEU C CA 1 ATOM 3483 C C . LEU C 1 96 ? 68.957 45.289 -10.500 1.00 28.80 ? 97 LEU C C 1 ATOM 3484 O O . LEU C 1 96 ? 69.183 46.506 -10.383 1.00 28.55 ? 97 LEU C O 1 ATOM 3485 C CB . LEU C 1 96 ? 69.865 43.727 -8.694 1.00 22.44 ? 97 LEU C CB 1 ATOM 3486 C CG . LEU C 1 96 ? 69.777 43.272 -7.216 1.00 26.18 ? 97 LEU C CG 1 ATOM 3487 C CD1 . LEU C 1 96 ? 71.068 42.563 -6.833 1.00 27.43 ? 97 LEU C CD1 1 ATOM 3488 C CD2 . LEU C 1 96 ? 69.509 44.465 -6.262 1.00 23.55 ? 97 LEU C CD2 1 ATOM 3489 N N . GLN C 1 97 ? 68.931 44.666 -11.685 1.00 25.39 ? 98 GLN C N 1 ATOM 3490 C CA . GLN C 1 97 ? 69.240 45.337 -12.965 1.00 25.20 ? 98 GLN C CA 1 ATOM 3491 C C . GLN C 1 97 ? 68.304 46.524 -13.310 1.00 26.24 ? 98 GLN C C 1 ATOM 3492 O O . GLN C 1 97 ? 68.687 47.359 -14.111 1.00 24.98 ? 98 GLN C O 1 ATOM 3493 C CB . GLN C 1 97 ? 69.287 44.308 -14.116 1.00 26.44 ? 98 GLN C CB 1 ATOM 3494 C CG . GLN C 1 97 ? 67.936 43.662 -14.451 1.00 27.54 ? 98 GLN C CG 1 ATOM 3495 C CD . GLN C 1 97 ? 67.876 43.282 -15.909 1.00 27.61 ? 98 GLN C CD 1 ATOM 3496 O OE1 . GLN C 1 97 ? 68.191 44.055 -16.775 1.00 27.09 ? 98 GLN C OE1 1 ATOM 3497 N NE2 . GLN C 1 97 ? 67.319 42.152 -16.232 1.00 25.99 ? 98 GLN C NE2 1 ATOM 3498 N N . HIS C 1 98 ? 67.104 46.593 -12.674 1.00 21.89 ? 99 HIS C N 1 ATOM 3499 C CA . HIS C 1 98 ? 66.109 47.630 -12.892 1.00 20.84 ? 99 HIS C CA 1 ATOM 3500 C C . HIS C 1 98 ? 66.353 48.940 -12.197 1.00 27.52 ? 99 HIS C C 1 ATOM 3501 O O . HIS C 1 98 ? 65.707 49.931 -12.530 1.00 28.44 ? 99 HIS C O 1 ATOM 3502 C CB . HIS C 1 98 ? 64.702 47.108 -12.591 1.00 21.62 ? 99 HIS C CB 1 ATOM 3503 C CG . HIS C 1 98 ? 64.293 46.030 -13.514 1.00 24.63 ? 99 HIS C CG 1 ATOM 3504 N ND1 . HIS C 1 98 ? 64.021 44.760 -13.046 1.00 26.52 ? 99 HIS C ND1 1 ATOM 3505 C CD2 . HIS C 1 98 ? 64.216 46.037 -14.871 1.00 25.80 ? 99 HIS C CD2 1 ATOM 3506 C CE1 . HIS C 1 98 ? 63.705 44.050 -14.120 1.00 25.52 ? 99 HIS C CE1 1 ATOM 3507 N NE2 . HIS C 1 98 ? 63.829 44.771 -15.241 1.00 25.77 ? 99 HIS C NE2 1 ATOM 3508 N N . GLU C 1 99 ? 67.264 48.964 -11.224 1.00 26.57 ? 100 GLU C N 1 ATOM 3509 C CA . GLU C 1 99 ? 67.591 50.179 -10.490 1.00 25.76 ? 100 GLU C CA 1 ATOM 3510 C C . GLU C 1 99 ? 68.205 51.206 -11.475 1.00 31.18 ? 100 GLU C C 1 ATOM 3511 O O . GLU C 1 99 ? 69.164 50.897 -12.217 1.00 31.38 ? 100 GLU C O 1 ATOM 3512 C CB . GLU C 1 99 ? 68.560 49.828 -9.362 1.00 26.60 ? 100 GLU C CB 1 ATOM 3513 C CG . GLU C 1 99 ? 69.039 51.034 -8.591 1.00 32.78 ? 100 GLU C CG 1 ATOM 3514 C CD . GLU C 1 99 ? 69.323 50.740 -7.132 1.00 50.58 ? 100 GLU C CD 1 ATOM 3515 O OE1 . GLU C 1 99 ? 68.381 50.359 -6.403 1.00 37.68 ? 100 GLU C OE1 1 ATOM 3516 O OE2 . GLU C 1 99 ? 70.493 50.892 -6.719 1.00 71.18 ? 100 GLU C OE2 1 ATOM 3517 N N . GLY C 1 100 ? 67.632 52.402 -11.469 1.00 26.51 ? 101 GLY C N 1 ATOM 3518 C CA . GLY C 1 100 ? 68.069 53.509 -12.302 1.00 24.63 ? 101 GLY C CA 1 ATOM 3519 C C . GLY C 1 100 ? 67.023 54.580 -12.452 1.00 28.35 ? 101 GLY C C 1 ATOM 3520 O O . GLY C 1 100 ? 66.103 54.678 -11.636 1.00 26.37 ? 101 GLY C O 1 ATOM 3521 N N . THR C 1 101 ? 67.180 55.400 -13.500 1.00 26.51 ? 102 THR C N 1 ATOM 3522 C CA . THR C 1 101 ? 66.334 56.554 -13.826 1.00 26.49 ? 102 THR C CA 1 ATOM 3523 C C . THR C 1 101 ? 65.431 56.232 -14.987 1.00 30.19 ? 102 THR C C 1 ATOM 3524 O O . THR C 1 101 ? 65.891 55.722 -16.011 1.00 30.66 ? 102 THR C O 1 ATOM 3525 C CB . THR C 1 101 ? 67.227 57.776 -14.095 1.00 35.89 ? 102 THR C CB 1 ATOM 3526 O OG1 . THR C 1 101 ? 67.995 57.970 -12.927 1.00 31.98 ? 102 THR C OG1 1 ATOM 3527 C CG2 . THR C 1 101 ? 66.435 59.049 -14.349 1.00 36.96 ? 102 THR C CG2 1 ATOM 3528 N N . TYR C 1 102 ? 64.148 56.512 -14.821 1.00 23.13 ? 103 TYR C N 1 ATOM 3529 C CA . TYR C 1 102 ? 63.152 56.260 -15.841 1.00 21.50 ? 103 TYR C CA 1 ATOM 3530 C C . TYR C 1 102 ? 62.517 57.617 -16.163 1.00 26.91 ? 103 TYR C C 1 ATOM 3531 O O . TYR C 1 102 ? 61.839 58.197 -15.309 1.00 27.24 ? 103 TYR C O 1 ATOM 3532 C CB . TYR C 1 102 ? 62.125 55.255 -15.303 1.00 21.69 ? 103 TYR C CB 1 ATOM 3533 C CG . TYR C 1 102 ? 62.676 53.851 -15.115 1.00 21.35 ? 103 TYR C CG 1 ATOM 3534 C CD1 . TYR C 1 102 ? 63.575 53.561 -14.089 1.00 21.32 ? 103 TYR C CD1 1 ATOM 3535 C CD2 . TYR C 1 102 ? 62.220 52.788 -15.893 1.00 22.00 ? 103 TYR C CD2 1 ATOM 3536 C CE1 . TYR C 1 102 ? 64.118 52.276 -13.938 1.00 20.84 ? 103 TYR C CE1 1 ATOM 3537 C CE2 . TYR C 1 102 ? 62.704 51.485 -15.706 1.00 18.60 ? 103 TYR C CE2 1 ATOM 3538 C CZ . TYR C 1 102 ? 63.678 51.239 -14.749 1.00 25.74 ? 103 TYR C CZ 1 ATOM 3539 O OH . TYR C 1 102 ? 64.197 49.960 -14.588 1.00 26.21 ? 103 TYR C OH 1 ATOM 3540 N N . THR C 1 103 ? 62.812 58.155 -17.358 1.00 22.91 ? 104 THR C N 1 ATOM 3541 C CA . THR C 1 103 ? 62.336 59.453 -17.809 1.00 22.69 ? 104 THR C CA 1 ATOM 3542 C C . THR C 1 103 ? 61.276 59.317 -18.874 1.00 29.84 ? 104 THR C C 1 ATOM 3543 O O . THR C 1 103 ? 61.512 58.691 -19.904 1.00 31.02 ? 104 THR C O 1 ATOM 3544 C CB . THR C 1 103 ? 63.512 60.323 -18.271 1.00 29.33 ? 104 THR C CB 1 ATOM 3545 O OG1 . THR C 1 103 ? 64.456 60.369 -17.214 1.00 28.36 ? 104 THR C OG1 1 ATOM 3546 C CG2 . THR C 1 103 ? 63.097 61.749 -18.691 1.00 22.95 ? 104 THR C CG2 1 ATOM 3547 N N . CYS C 1 104 ? 60.115 59.900 -18.630 1.00 28.09 ? 105 CYS C N 1 ATOM 3548 C CA . CYS C 1 104 ? 59.038 59.894 -19.593 1.00 31.75 ? 105 CYS C CA 1 ATOM 3549 C C . CYS C 1 104 ? 59.031 61.258 -20.287 1.00 35.17 ? 105 CYS C C 1 ATOM 3550 O O . CYS C 1 104 ? 58.831 62.295 -19.637 1.00 34.49 ? 105 CYS C O 1 ATOM 3551 C CB . CYS C 1 104 ? 57.706 59.590 -18.927 1.00 35.55 ? 105 CYS C CB 1 ATOM 3552 S SG . CYS C 1 104 ? 56.363 59.345 -20.097 1.00 43.07 ? 105 CYS C SG 1 ATOM 3553 N N . GLU C 1 105 ? 59.349 61.262 -21.580 1.00 29.79 ? 106 GLU C N 1 ATOM 3554 C CA . GLU C 1 105 ? 59.386 62.447 -22.419 1.00 28.24 ? 106 GLU C CA 1 ATOM 3555 C C . GLU C 1 105 ? 58.105 62.458 -23.207 1.00 31.15 ? 106 GLU C C 1 ATOM 3556 O O . GLU C 1 105 ? 57.808 61.488 -23.891 1.00 28.32 ? 106 GLU C O 1 ATOM 3557 C CB . GLU C 1 105 ? 60.566 62.419 -23.370 1.00 29.32 ? 106 GLU C CB 1 ATOM 3558 C CG . GLU C 1 105 ? 61.910 62.672 -22.710 1.00 42.53 ? 106 GLU C CG 1 ATOM 3559 C CD . GLU C 1 105 ? 63.091 62.860 -23.656 1.00 67.76 ? 106 GLU C CD 1 ATOM 3560 O OE1 . GLU C 1 105 ? 62.963 62.570 -24.871 1.00 69.89 ? 106 GLU C OE1 1 ATOM 3561 O OE2 . GLU C 1 105 ? 64.171 63.253 -23.160 1.00 60.33 ? 106 GLU C OE2 1 ATOM 3562 N N . ILE C 1 106 ? 57.312 63.524 -23.053 1.00 30.15 ? 107 ILE C N 1 ATOM 3563 C CA . ILE C 1 106 ? 56.046 63.660 -23.753 1.00 31.31 ? 107 ILE C CA 1 ATOM 3564 C C . ILE C 1 106 ? 56.148 64.776 -24.788 1.00 37.26 ? 107 ILE C C 1 ATOM 3565 O O . ILE C 1 106 ? 56.565 65.887 -24.455 1.00 37.04 ? 107 ILE C O 1 ATOM 3566 C CB . ILE C 1 106 ? 54.851 63.875 -22.784 1.00 34.02 ? 107 ILE C CB 1 ATOM 3567 C CG1 . ILE C 1 106 ? 54.796 62.796 -21.653 1.00 34.93 ? 107 ILE C CG1 1 ATOM 3568 C CG2 . ILE C 1 106 ? 53.511 63.996 -23.531 1.00 30.77 ? 107 ILE C CG2 1 ATOM 3569 C CD1 . ILE C 1 106 ? 54.953 63.410 -20.273 1.00 38.48 ? 107 ILE C CD1 1 ATOM 3570 N N . VAL C 1 107 ? 55.772 64.472 -26.035 1.00 33.95 ? 108 VAL C N 1 ATOM 3571 C CA . VAL C 1 107 ? 55.715 65.452 -27.118 1.00 34.62 ? 108 VAL C CA 1 ATOM 3572 C C . VAL C 1 107 ? 54.226 65.736 -27.392 1.00 38.90 ? 108 VAL C C 1 ATOM 3573 O O . VAL C 1 107 ? 53.441 64.824 -27.659 1.00 36.45 ? 108 VAL C O 1 ATOM 3574 C CB . VAL C 1 107 ? 56.496 65.041 -28.401 1.00 38.53 ? 108 VAL C CB 1 ATOM 3575 C CG1 . VAL C 1 107 ? 56.147 65.952 -29.583 1.00 38.64 ? 108 VAL C CG1 1 ATOM 3576 C CG2 . VAL C 1 107 ? 58.006 65.024 -28.156 1.00 37.19 ? 108 VAL C CG2 1 ATOM 3577 N N . THR C 1 108 ? 53.841 66.997 -27.248 1.00 37.45 ? 109 THR C N 1 ATOM 3578 C CA . THR C 1 108 ? 52.473 67.451 -27.500 1.00 39.16 ? 109 THR C CA 1 ATOM 3579 C C . THR C 1 108 ? 52.562 68.498 -28.653 1.00 45.39 ? 109 THR C C 1 ATOM 3580 O O . THR C 1 108 ? 53.671 69.001 -28.925 1.00 42.60 ? 109 THR C O 1 ATOM 3581 C CB . THR C 1 108 ? 51.882 68.123 -26.227 1.00 47.48 ? 109 THR C CB 1 ATOM 3582 O OG1 . THR C 1 108 ? 52.597 69.350 -25.964 1.00 52.96 ? 109 THR C OG1 1 ATOM 3583 C CG2 . THR C 1 108 ? 51.871 67.203 -25.015 1.00 44.19 ? 109 THR C CG2 1 ATOM 3584 N N . PRO C 1 109 ? 51.420 68.930 -29.257 1.00 45.13 ? 110 PRO C N 1 ATOM 3585 C CA . PRO C 1 109 ? 51.504 69.986 -30.289 1.00 46.11 ? 110 PRO C CA 1 ATOM 3586 C C . PRO C 1 109 ? 52.128 71.295 -29.798 1.00 52.44 ? 110 PRO C C 1 ATOM 3587 O O . PRO C 1 109 ? 52.734 71.986 -30.613 1.00 53.60 ? 110 PRO C O 1 ATOM 3588 C CB . PRO C 1 109 ? 50.054 70.180 -30.714 1.00 47.50 ? 110 PRO C CB 1 ATOM 3589 C CG . PRO C 1 109 ? 49.366 68.891 -30.346 1.00 51.06 ? 110 PRO C CG 1 ATOM 3590 C CD . PRO C 1 109 ? 50.025 68.472 -29.076 1.00 46.07 ? 110 PRO C CD 1 ATOM 3591 N N . GLU C 1 110 ? 52.066 71.591 -28.468 1.00 48.33 ? 111 GLU C N 1 ATOM 3592 C CA . GLU C 1 110 ? 52.610 72.825 -27.858 1.00 47.51 ? 111 GLU C CA 1 ATOM 3593 C C . GLU C 1 110 ? 54.083 72.741 -27.508 1.00 49.96 ? 111 GLU C C 1 ATOM 3594 O O . GLU C 1 110 ? 54.774 73.761 -27.480 1.00 50.88 ? 111 GLU C O 1 ATOM 3595 C CB . GLU C 1 110 ? 51.820 73.206 -26.596 1.00 49.01 ? 111 GLU C CB 1 ATOM 3596 C CG . GLU C 1 110 ? 50.399 73.679 -26.865 1.00 60.65 ? 111 GLU C CG 1 ATOM 3597 C CD . GLU C 1 110 ? 49.429 72.644 -27.386 1.00 75.96 ? 111 GLU C CD 1 ATOM 3598 O OE1 . GLU C 1 110 ? 49.354 71.544 -26.792 1.00 64.02 ? 111 GLU C OE1 1 ATOM 3599 O OE2 . GLU C 1 110 ? 48.753 72.928 -28.402 1.00 79.09 ? 111 GLU C OE2 1 ATOM 3600 N N . GLY C 1 111 ? 54.556 71.547 -27.202 1.00 44.96 ? 112 GLY C N 1 ATOM 3601 C CA . GLY C 1 111 ? 55.952 71.380 -26.809 1.00 43.82 ? 112 GLY C CA 1 ATOM 3602 C C . GLY C 1 111 ? 56.213 70.133 -25.994 1.00 43.38 ? 112 GLY C C 1 ATOM 3603 O O . GLY C 1 111 ? 55.494 69.140 -26.117 1.00 43.10 ? 112 GLY C O 1 ATOM 3604 N N . ASN C 1 112 ? 57.249 70.183 -25.170 1.00 36.24 ? 113 ASN C N 1 ATOM 3605 C CA . ASN C 1 112 ? 57.685 69.039 -24.397 1.00 34.86 ? 113 ASN C CA 1 ATOM 3606 C C . ASN C 1 112 ? 57.417 69.095 -22.907 1.00 36.30 ? 113 ASN C C 1 ATOM 3607 O O . ASN C 1 112 ? 57.689 70.096 -22.228 1.00 35.08 ? 113 ASN C O 1 ATOM 3608 C CB . ASN C 1 112 ? 59.168 68.761 -24.638 1.00 38.76 ? 113 ASN C CB 1 ATOM 3609 C CG . ASN C 1 112 ? 59.608 68.733 -26.089 1.00 50.24 ? 113 ASN C CG 1 ATOM 3610 O OD1 . ASN C 1 112 ? 59.002 68.108 -26.946 1.00 33.93 ? 113 ASN C OD1 1 ATOM 3611 N ND2 . ASN C 1 112 ? 60.694 69.406 -26.380 1.00 44.42 ? 113 ASN C ND2 1 ATOM 3612 N N . LEU C 1 113 ? 56.952 67.955 -22.405 1.00 30.84 ? 114 LEU C N 1 ATOM 3613 C CA . LEU C 1 113 ? 56.701 67.675 -20.997 1.00 30.06 ? 114 LEU C CA 1 ATOM 3614 C C . LEU C 1 113 ? 57.564 66.488 -20.546 1.00 34.86 ? 114 LEU C C 1 ATOM 3615 O O . LEU C 1 113 ? 58.000 65.690 -21.384 1.00 35.67 ? 114 LEU C O 1 ATOM 3616 C CB . LEU C 1 113 ? 55.204 67.374 -20.769 1.00 29.20 ? 114 LEU C CB 1 ATOM 3617 C CG . LEU C 1 113 ? 54.170 68.325 -21.432 1.00 30.51 ? 114 LEU C CG 1 ATOM 3618 C CD1 . LEU C 1 113 ? 52.785 67.777 -21.280 1.00 28.33 ? 114 LEU C CD1 1 ATOM 3619 C CD2 . LEU C 1 113 ? 54.267 69.753 -20.885 1.00 28.96 ? 114 LEU C CD2 1 ATOM 3620 N N . GLU C 1 114 ? 57.851 66.386 -19.250 1.00 31.70 ? 115 GLU C N 1 ATOM 3621 C CA . GLU C 1 114 ? 58.604 65.242 -18.699 1.00 31.90 ? 115 GLU C CA 1 ATOM 3622 C C . GLU C 1 114 ? 58.274 64.848 -17.287 1.00 33.70 ? 115 GLU C C 1 ATOM 3623 O O . GLU C 1 114 ? 57.962 65.706 -16.472 1.00 33.96 ? 115 GLU C O 1 ATOM 3624 C CB . GLU C 1 114 ? 60.125 65.310 -18.905 1.00 33.11 ? 115 GLU C CB 1 ATOM 3625 C CG . GLU C 1 114 ? 60.847 66.258 -17.982 1.00 45.48 ? 115 GLU C CG 1 ATOM 3626 C CD . GLU C 1 114 ? 62.348 66.092 -17.883 1.00 59.22 ? 115 GLU C CD 1 ATOM 3627 O OE1 . GLU C 1 114 ? 62.943 65.502 -18.815 1.00 53.22 ? 115 GLU C OE1 1 ATOM 3628 O OE2 . GLU C 1 114 ? 62.928 66.577 -16.881 1.00 47.81 ? 115 GLU C OE2 1 ATOM 3629 N N . LYS C 1 115 ? 58.356 63.547 -17.015 1.00 28.83 ? 116 LYS C N 1 ATOM 3630 C CA . LYS C 1 115 ? 58.183 62.945 -15.698 1.00 29.29 ? 116 LYS C CA 1 ATOM 3631 C C . LYS C 1 115 ? 59.449 62.082 -15.446 1.00 32.87 ? 116 LYS C C 1 ATOM 3632 O O . LYS C 1 115 ? 59.778 61.249 -16.264 1.00 31.48 ? 116 LYS C O 1 ATOM 3633 C CB . LYS C 1 115 ? 56.896 62.083 -15.660 1.00 31.10 ? 116 LYS C CB 1 ATOM 3634 C CG . LYS C 1 115 ? 56.530 61.556 -14.283 1.00 33.49 ? 116 LYS C CG 1 ATOM 3635 C CD . LYS C 1 115 ? 56.086 62.664 -13.352 1.00 37.38 ? 116 LYS C CD 1 ATOM 3636 C CE . LYS C 1 115 ? 55.414 62.144 -12.100 1.00 28.23 ? 116 LYS C CE 1 ATOM 3637 N NZ . LYS C 1 115 ? 55.268 63.217 -11.084 1.00 37.07 ? 116 LYS C NZ 1 ATOM 3638 N N . VAL C 1 116 ? 60.138 62.290 -14.329 1.00 30.17 ? 117 VAL C N 1 ATOM 3639 C CA . VAL C 1 116 ? 61.334 61.541 -13.962 1.00 29.35 ? 117 VAL C CA 1 ATOM 3640 C C . VAL C 1 116 ? 61.093 60.701 -12.692 1.00 35.26 ? 117 VAL C C 1 ATOM 3641 O O . VAL C 1 116 ? 60.607 61.224 -11.684 1.00 35.02 ? 117 VAL C O 1 ATOM 3642 C CB . VAL C 1 116 ? 62.575 62.470 -13.802 1.00 31.59 ? 117 VAL C CB 1 ATOM 3643 C CG1 . VAL C 1 116 ? 63.833 61.656 -13.515 1.00 30.76 ? 117 VAL C CG1 1 ATOM 3644 C CG2 . VAL C 1 116 ? 62.778 63.384 -15.028 1.00 30.49 ? 117 VAL C CG2 1 ATOM 3645 N N . TYR C 1 117 ? 61.438 59.401 -12.756 1.00 31.30 ? 118 TYR C N 1 ATOM 3646 C CA . TYR C 1 117 ? 61.415 58.467 -11.631 1.00 30.08 ? 118 TYR C CA 1 ATOM 3647 C C . TYR C 1 117 ? 62.807 57.968 -11.359 1.00 31.39 ? 118 TYR C C 1 ATOM 3648 O O . TYR C 1 117 ? 63.524 57.596 -12.277 1.00 29.26 ? 118 TYR C O 1 ATOM 3649 C CB . TYR C 1 117 ? 60.536 57.237 -11.901 1.00 30.50 ? 118 TYR C CB 1 ATOM 3650 C CG . TYR C 1 117 ? 59.071 57.551 -11.934 1.00 32.24 ? 118 TYR C CG 1 ATOM 3651 C CD1 . TYR C 1 117 ? 58.312 57.553 -10.763 1.00 34.18 ? 118 TYR C CD1 1 ATOM 3652 C CD2 . TYR C 1 117 ? 58.431 57.857 -13.133 1.00 32.27 ? 118 TYR C CD2 1 ATOM 3653 C CE1 . TYR C 1 117 ? 56.957 57.859 -10.786 1.00 32.14 ? 118 TYR C CE1 1 ATOM 3654 C CE2 . TYR C 1 117 ? 57.076 58.169 -13.164 1.00 32.51 ? 118 TYR C CE2 1 ATOM 3655 C CZ . TYR C 1 117 ? 56.344 58.157 -11.987 1.00 38.05 ? 118 TYR C CZ 1 ATOM 3656 O OH . TYR C 1 117 ? 55.002 58.408 -11.996 1.00 38.28 ? 118 TYR C OH 1 ATOM 3657 N N . ASP C 1 118 ? 63.158 57.906 -10.094 1.00 29.87 ? 119 ASP C N 1 ATOM 3658 C CA . ASP C 1 118 ? 64.393 57.341 -9.601 1.00 31.03 ? 119 ASP C CA 1 ATOM 3659 C C . ASP C 1 118 ? 63.948 56.050 -8.900 1.00 33.89 ? 119 ASP C C 1 ATOM 3660 O O . ASP C 1 118 ? 63.315 56.105 -7.857 1.00 32.71 ? 119 ASP C O 1 ATOM 3661 C CB . ASP C 1 118 ? 65.004 58.338 -8.631 1.00 35.45 ? 119 ASP C CB 1 ATOM 3662 C CG . ASP C 1 118 ? 66.442 58.118 -8.267 1.00 64.36 ? 119 ASP C CG 1 ATOM 3663 O OD1 . ASP C 1 118 ? 66.807 56.958 -7.966 1.00 64.38 ? 119 ASP C OD1 1 ATOM 3664 O OD2 . ASP C 1 118 ? 67.189 59.123 -8.189 1.00 82.35 ? 119 ASP C OD2 1 ATOM 3665 N N . LEU C 1 119 ? 64.156 54.902 -9.547 1.00 31.41 ? 120 LEU C N 1 ATOM 3666 C CA . LEU C 1 119 ? 63.750 53.598 -9.042 1.00 30.98 ? 120 LEU C CA 1 ATOM 3667 C C . LEU C 1 119 ? 64.860 52.911 -8.236 1.00 29.64 ? 120 LEU C C 1 ATOM 3668 O O . LEU C 1 119 ? 65.946 52.694 -8.740 1.00 27.59 ? 120 LEU C O 1 ATOM 3669 C CB . LEU C 1 119 ? 63.292 52.729 -10.214 1.00 32.14 ? 120 LEU C CB 1 ATOM 3670 C CG . LEU C 1 119 ? 62.489 51.465 -9.872 1.00 39.56 ? 120 LEU C CG 1 ATOM 3671 C CD1 . LEU C 1 119 ? 61.491 51.200 -10.914 1.00 42.01 ? 120 LEU C CD1 1 ATOM 3672 C CD2 . LEU C 1 119 ? 63.367 50.266 -9.890 1.00 43.31 ? 120 LEU C CD2 1 ATOM 3673 N N . GLN C 1 120 ? 64.575 52.600 -6.965 1.00 26.89 ? 121 GLN C N 1 ATOM 3674 C CA . GLN C 1 120 ? 65.488 51.917 -6.030 1.00 25.78 ? 121 GLN C CA 1 ATOM 3675 C C . GLN C 1 120 ? 64.933 50.522 -5.796 1.00 28.03 ? 121 GLN C C 1 ATOM 3676 O O . GLN C 1 120 ? 63.728 50.371 -5.563 1.00 25.75 ? 121 GLN C O 1 ATOM 3677 C CB . GLN C 1 120 ? 65.562 52.651 -4.681 1.00 26.94 ? 121 GLN C CB 1 ATOM 3678 C CG . GLN C 1 120 ? 66.210 54.031 -4.724 1.00 61.07 ? 121 GLN C CG 1 ATOM 3679 C CD . GLN C 1 120 ? 67.716 53.925 -4.812 1.00 102.76 ? 121 GLN C CD 1 ATOM 3680 O OE1 . GLN C 1 120 ? 68.388 53.415 -3.899 1.00 103.90 ? 121 GLN C OE1 1 ATOM 3681 N NE2 . GLN C 1 120 ? 68.272 54.367 -5.935 1.00 94.97 ? 121 GLN C NE2 1 ATOM 3682 N N . VAL C 1 121 ? 65.795 49.504 -5.856 1.00 24.74 ? 122 VAL C N 1 ATOM 3683 C CA . VAL C 1 121 ? 65.388 48.115 -5.617 1.00 23.49 ? 122 VAL C CA 1 ATOM 3684 C C . VAL C 1 121 ? 65.768 47.708 -4.199 1.00 28.90 ? 122 VAL C C 1 ATOM 3685 O O . VAL C 1 121 ? 66.897 47.932 -3.777 1.00 28.10 ? 122 VAL C O 1 ATOM 3686 C CB . VAL C 1 121 ? 65.920 47.145 -6.698 1.00 26.52 ? 122 VAL C CB 1 ATOM 3687 C CG1 . VAL C 1 121 ? 65.506 45.696 -6.391 1.00 25.25 ? 122 VAL C CG1 1 ATOM 3688 C CG2 . VAL C 1 121 ? 65.455 47.589 -8.098 1.00 26.40 ? 122 VAL C CG2 1 ATOM 3689 N N . LEU C 1 122 ? 64.793 47.199 -3.443 1.00 27.58 ? 123 LEU C N 1 ATOM 3690 C CA . LEU C 1 122 ? 64.969 46.743 -2.063 1.00 27.29 ? 123 LEU C CA 1 ATOM 3691 C C . LEU C 1 122 ? 65.009 45.221 -2.056 1.00 30.46 ? 123 LEU C C 1 ATOM 3692 O O . LEU C 1 122 ? 64.166 44.560 -2.681 1.00 29.49 ? 123 LEU C O 1 ATOM 3693 C CB . LEU C 1 122 ? 63.843 47.240 -1.134 1.00 26.98 ? 123 LEU C CB 1 ATOM 3694 C CG . LEU C 1 122 ? 63.560 48.739 -1.098 1.00 31.23 ? 123 LEU C CG 1 ATOM 3695 C CD1 . LEU C 1 122 ? 62.382 49.021 -0.204 1.00 31.97 ? 123 LEU C CD1 1 ATOM 3696 C CD2 . LEU C 1 122 ? 64.760 49.535 -0.637 1.00 32.78 ? 123 LEU C CD2 1 ATOM 3697 N N . VAL C 1 123 ? 65.996 44.673 -1.361 1.00 24.35 ? 124 VAL C N 1 ATOM 3698 C CA . VAL C 1 123 ? 66.146 43.234 -1.225 1.00 22.23 ? 124 VAL C CA 1 ATOM 3699 C C . VAL C 1 123 ? 66.029 42.866 0.278 1.00 26.63 ? 124 VAL C C 1 ATOM 3700 O O . VAL C 1 123 ? 66.891 43.241 1.081 1.00 25.84 ? 124 VAL C O 1 ATOM 3701 C CB . VAL C 1 123 ? 67.500 42.732 -1.828 1.00 24.04 ? 124 VAL C CB 1 ATOM 3702 C CG1 . VAL C 1 123 ? 67.580 41.216 -1.793 1.00 22.75 ? 124 VAL C CG1 1 ATOM 3703 C CG2 . VAL C 1 123 ? 67.730 43.251 -3.248 1.00 22.76 ? 124 VAL C CG2 1 ATOM 3704 N N . PRO C 1 124 ? 64.975 42.145 0.686 1.00 24.94 ? 125 PRO C N 1 ATOM 3705 C CA . PRO C 1 124 ? 64.891 41.668 2.087 1.00 23.20 ? 125 PRO C CA 1 ATOM 3706 C C . PRO C 1 124 ? 66.044 40.693 2.416 1.00 27.94 ? 125 PRO C C 1 ATOM 3707 O O . PRO C 1 124 ? 66.332 39.814 1.587 1.00 26.90 ? 125 PRO C O 1 ATOM 3708 C CB . PRO C 1 124 ? 63.551 40.917 2.114 1.00 23.18 ? 125 PRO C CB 1 ATOM 3709 C CG . PRO C 1 124 ? 62.816 41.378 0.927 1.00 27.89 ? 125 PRO C CG 1 ATOM 3710 C CD . PRO C 1 124 ? 63.839 41.641 -0.109 1.00 25.77 ? 125 PRO C CD 1 ATOM 3711 N N . PRO C 1 125 ? 66.735 40.810 3.582 1.00 24.41 ? 126 PRO C N 1 ATOM 3712 C CA . PRO C 1 125 ? 67.823 39.861 3.868 1.00 24.33 ? 126 PRO C CA 1 ATOM 3713 C C . PRO C 1 125 ? 67.275 38.465 4.209 1.00 29.13 ? 126 PRO C C 1 ATOM 3714 O O . PRO C 1 125 ? 66.150 38.343 4.681 1.00 28.22 ? 126 PRO C O 1 ATOM 3715 C CB . PRO C 1 125 ? 68.556 40.509 5.043 1.00 25.11 ? 126 PRO C CB 1 ATOM 3716 C CG . PRO C 1 125 ? 67.477 41.288 5.767 1.00 28.36 ? 126 PRO C CG 1 ATOM 3717 C CD . PRO C 1 125 ? 66.556 41.777 4.682 1.00 24.76 ? 126 PRO C CD 1 ATOM 3718 N N . GLU C 1 126 ? 68.055 37.415 3.918 1.00 27.02 ? 127 GLU C N 1 ATOM 3719 C CA . GLU C 1 126 ? 67.687 36.044 4.291 1.00 26.18 ? 127 GLU C CA 1 ATOM 3720 C C . GLU C 1 126 ? 68.443 35.803 5.587 1.00 31.53 ? 127 GLU C C 1 ATOM 3721 O O . GLU C 1 126 ? 69.664 36.015 5.643 1.00 31.52 ? 127 GLU C O 1 ATOM 3722 C CB . GLU C 1 126 ? 68.061 35.009 3.222 1.00 26.84 ? 127 GLU C CB 1 ATOM 3723 C CG . GLU C 1 126 ? 67.220 35.053 1.967 1.00 33.01 ? 127 GLU C CG 1 ATOM 3724 C CD . GLU C 1 126 ? 65.703 35.010 2.065 1.00 63.82 ? 127 GLU C CD 1 ATOM 3725 O OE1 . GLU C 1 126 ? 65.155 34.777 3.169 1.00 64.33 ? 127 GLU C OE1 1 ATOM 3726 O OE2 . GLU C 1 126 ? 65.057 35.233 1.018 1.00 60.63 ? 127 GLU C OE2 1 ATOM 3727 N N . VAL C 1 127 ? 67.706 35.467 6.651 1.00 27.36 ? 128 VAL C N 1 ATOM 3728 C CA . VAL C 1 127 ? 68.294 35.323 7.979 1.00 27.51 ? 128 VAL C CA 1 ATOM 3729 C C . VAL C 1 127 ? 68.556 33.908 8.425 1.00 29.13 ? 128 VAL C C 1 ATOM 3730 O O . VAL C 1 127 ? 67.866 32.980 8.049 1.00 27.94 ? 128 VAL C O 1 ATOM 3731 C CB . VAL C 1 127 ? 67.556 36.150 9.092 1.00 31.64 ? 128 VAL C CB 1 ATOM 3732 C CG1 . VAL C 1 127 ? 67.393 37.622 8.672 1.00 30.88 ? 128 VAL C CG1 1 ATOM 3733 C CG2 . VAL C 1 127 ? 66.193 35.521 9.407 1.00 31.59 ? 128 VAL C CG2 1 ATOM 3734 N N . THR C 1 128 ? 69.491 33.784 9.334 1.00 27.48 ? 129 THR C N 1 ATOM 3735 C CA . THR C 1 128 ? 69.842 32.543 9.994 1.00 27.11 ? 129 THR C CA 1 ATOM 3736 C C . THR C 1 128 ? 70.338 32.840 11.387 1.00 28.63 ? 129 THR C C 1 ATOM 3737 O O . THR C 1 128 ? 70.893 33.916 11.644 1.00 26.00 ? 129 THR C O 1 ATOM 3738 C CB . THR C 1 128 ? 70.731 31.635 9.156 1.00 37.97 ? 129 THR C CB 1 ATOM 3739 O OG1 . THR C 1 128 ? 70.628 30.323 9.735 1.00 48.82 ? 129 THR C OG1 1 ATOM 3740 C CG2 . THR C 1 128 ? 72.191 32.123 9.073 1.00 29.85 ? 129 THR C CG2 1 ATOM 3741 N N . TYR C 1 129 ? 70.085 31.891 12.298 1.00 25.70 ? 130 TYR C N 1 ATOM 3742 C CA . TYR C 1 129 ? 70.445 31.992 13.701 1.00 24.40 ? 130 TYR C CA 1 ATOM 3743 C C . TYR C 1 129 ? 70.988 30.652 14.148 1.00 30.37 ? 130 TYR C C 1 ATOM 3744 O O . TYR C 1 129 ? 70.451 29.607 13.760 1.00 30.32 ? 130 TYR C O 1 ATOM 3745 C CB . TYR C 1 129 ? 69.184 32.290 14.540 1.00 24.49 ? 130 TYR C CB 1 ATOM 3746 C CG . TYR C 1 129 ? 68.256 33.363 14.022 1.00 23.24 ? 130 TYR C CG 1 ATOM 3747 C CD1 . TYR C 1 129 ? 67.263 33.062 13.089 1.00 24.15 ? 130 TYR C CD1 1 ATOM 3748 C CD2 . TYR C 1 129 ? 68.343 34.676 14.486 1.00 22.60 ? 130 TYR C CD2 1 ATOM 3749 C CE1 . TYR C 1 129 ? 66.381 34.041 12.622 1.00 24.39 ? 130 TYR C CE1 1 ATOM 3750 C CE2 . TYR C 1 129 ? 67.455 35.665 14.030 1.00 22.96 ? 130 TYR C CE2 1 ATOM 3751 C CZ . TYR C 1 129 ? 66.471 35.336 13.109 1.00 26.41 ? 130 TYR C CZ 1 ATOM 3752 O OH . TYR C 1 129 ? 65.561 36.267 12.692 1.00 33.59 ? 130 TYR C OH 1 ATOM 3753 N N . PHE C 1 130 ? 72.003 30.661 15.001 1.00 27.21 ? 131 PHE C N 1 ATOM 3754 C CA . PHE C 1 130 ? 72.487 29.417 15.548 1.00 27.99 ? 131 PHE C CA 1 ATOM 3755 C C . PHE C 1 130 ? 73.358 29.559 16.746 1.00 31.84 ? 131 PHE C C 1 ATOM 3756 O O . PHE C 1 130 ? 74.133 30.500 16.806 1.00 30.36 ? 131 PHE C O 1 ATOM 3757 C CB . PHE C 1 130 ? 73.173 28.531 14.489 1.00 31.04 ? 131 PHE C CB 1 ATOM 3758 C CG . PHE C 1 130 ? 74.275 29.148 13.671 1.00 31.98 ? 131 PHE C CG 1 ATOM 3759 C CD1 . PHE C 1 130 ? 73.989 29.797 12.472 1.00 33.85 ? 131 PHE C CD1 1 ATOM 3760 C CD2 . PHE C 1 130 ? 75.610 28.980 14.037 1.00 34.88 ? 131 PHE C CD2 1 ATOM 3761 C CE1 . PHE C 1 130 ? 75.007 30.361 11.703 1.00 37.40 ? 131 PHE C CE1 1 ATOM 3762 C CE2 . PHE C 1 130 ? 76.645 29.513 13.249 1.00 36.61 ? 131 PHE C CE2 1 ATOM 3763 C CZ . PHE C 1 130 ? 76.337 30.193 12.076 1.00 35.91 ? 131 PHE C CZ 1 ATOM 3764 N N . PRO C 1 131 ? 73.292 28.616 17.716 1.00 31.68 ? 132 PRO C N 1 ATOM 3765 C CA . PRO C 1 131 ? 74.263 28.673 18.832 1.00 31.55 ? 132 PRO C CA 1 ATOM 3766 C C . PRO C 1 131 ? 75.611 28.161 18.357 1.00 35.21 ? 132 PRO C C 1 ATOM 3767 O O . PRO C 1 131 ? 75.680 27.380 17.430 1.00 35.46 ? 132 PRO C O 1 ATOM 3768 C CB . PRO C 1 131 ? 73.668 27.738 19.895 1.00 33.02 ? 132 PRO C CB 1 ATOM 3769 C CG . PRO C 1 131 ? 72.544 26.988 19.227 1.00 36.40 ? 132 PRO C CG 1 ATOM 3770 C CD . PRO C 1 131 ? 72.422 27.413 17.798 1.00 32.08 ? 132 PRO C CD 1 ATOM 3771 N N . GLY C 1 132 ? 76.669 28.636 18.965 1.00 35.00 ? 133 GLY C N 1 ATOM 3772 C CA . GLY C 1 132 ? 78.026 28.199 18.666 1.00 35.64 ? 133 GLY C CA 1 ATOM 3773 C C . GLY C 1 132 ? 78.661 27.539 19.877 1.00 45.22 ? 133 GLY C C 1 ATOM 3774 O O . GLY C 1 132 ? 78.006 27.327 20.907 1.00 44.28 ? 133 GLY C O 1 ATOM 3775 N N . LYS C 1 133 ? 79.953 27.239 19.784 1.00 46.36 ? 134 LYS C N 1 ATOM 3776 C CA . LYS C 1 133 ? 80.674 26.626 20.903 1.00 47.62 ? 134 LYS C CA 1 ATOM 3777 C C . LYS C 1 133 ? 80.973 27.677 21.979 1.00 52.37 ? 134 LYS C C 1 ATOM 3778 O O . LYS C 1 133 ? 81.192 28.845 21.654 1.00 53.68 ? 134 LYS C O 1 ATOM 3779 C CB . LYS C 1 133 ? 81.996 25.987 20.423 1.00 51.19 ? 134 LYS C CB 1 ATOM 3780 C CG . LYS C 1 133 ? 81.823 24.815 19.472 1.00 74.62 ? 134 LYS C CG 1 ATOM 3781 C CD . LYS C 1 133 ? 83.180 24.243 19.058 1.00 89.03 ? 134 LYS C CD 1 ATOM 3782 C CE . LYS C 1 133 ? 83.082 23.332 17.848 1.00 103.67 ? 134 LYS C CE 1 ATOM 3783 N NZ . LYS C 1 133 ? 84.397 23.132 17.182 1.00 111.45 ? 134 LYS C NZ 1 ATOM 3784 N N . ASN C 1 134 ? 80.986 27.257 23.245 1.00 46.42 ? 135 ASN C N 1 ATOM 3785 C CA . ASN C 1 134 ? 81.329 28.089 24.396 1.00 45.77 ? 135 ASN C CA 1 ATOM 3786 C C . ASN C 1 134 ? 80.459 29.325 24.599 1.00 45.67 ? 135 ASN C C 1 ATOM 3787 O O . ASN C 1 134 ? 80.977 30.437 24.688 1.00 44.21 ? 135 ASN C O 1 ATOM 3788 C CB . ASN C 1 134 ? 82.868 28.414 24.465 1.00 50.29 ? 135 ASN C CB 1 ATOM 3789 C CG . ASN C 1 134 ? 83.377 28.941 25.822 1.00 81.84 ? 135 ASN C CG 1 ATOM 3790 O OD1 . ASN C 1 134 ? 82.717 28.819 26.883 1.00 71.79 ? 135 ASN C OD1 1 ATOM 3791 N ND2 . ASN C 1 134 ? 84.569 29.556 25.819 1.00 74.79 ? 135 ASN C ND2 1 ATOM 3792 N N . ARG C 1 135 ? 79.145 29.122 24.757 1.00 41.65 ? 136 ARG C N 1 ATOM 3793 C CA . ARG C 1 135 ? 78.185 30.201 25.020 1.00 41.48 ? 136 ARG C CA 1 ATOM 3794 C C . ARG C 1 135 ? 78.210 31.378 23.995 1.00 41.87 ? 136 ARG C C 1 ATOM 3795 O O . ARG C 1 135 ? 78.135 32.550 24.365 1.00 40.78 ? 136 ARG C O 1 ATOM 3796 C CB . ARG C 1 135 ? 78.326 30.701 26.473 1.00 44.28 ? 136 ARG C CB 1 ATOM 3797 C CG . ARG C 1 135 ? 77.872 29.652 27.507 1.00 56.10 ? 136 ARG C CG 1 ATOM 3798 C CD . ARG C 1 135 ? 78.053 30.098 28.955 1.00 52.30 ? 136 ARG C CD 1 ATOM 3799 N NE . ARG C 1 135 ? 77.470 31.414 29.224 1.00 56.32 ? 136 ARG C NE 1 ATOM 3800 C CZ . ARG C 1 135 ? 76.182 31.627 29.471 1.00 68.00 ? 136 ARG C CZ 1 ATOM 3801 N NH1 . ARG C 1 135 ? 75.323 30.613 29.479 1.00 55.76 ? 136 ARG C NH1 1 ATOM 3802 N NH2 . ARG C 1 135 ? 75.738 32.855 29.694 1.00 51.22 ? 136 ARG C NH2 1 ATOM 3803 N N . THR C 1 136 ? 78.356 31.046 22.715 1.00 36.42 ? 137 THR C N 1 ATOM 3804 C CA . THR C 1 136 ? 78.326 32.017 21.631 1.00 34.64 ? 137 THR C CA 1 ATOM 3805 C C . THR C 1 136 ? 77.048 31.803 20.802 1.00 36.35 ? 137 THR C C 1 ATOM 3806 O O . THR C 1 136 ? 76.443 30.730 20.830 1.00 35.53 ? 137 THR C O 1 ATOM 3807 C CB . THR C 1 136 ? 79.589 31.966 20.775 1.00 38.75 ? 137 THR C CB 1 ATOM 3808 O OG1 . THR C 1 136 ? 79.633 30.735 20.063 1.00 43.04 ? 137 THR C OG1 1 ATOM 3809 C CG2 . THR C 1 136 ? 80.874 32.229 21.567 1.00 32.78 ? 137 THR C CG2 1 ATOM 3810 N N . ALA C 1 137 ? 76.618 32.838 20.101 1.00 30.76 ? 138 ALA C N 1 ATOM 3811 C CA . ALA C 1 137 ? 75.459 32.751 19.218 1.00 28.54 ? 138 ALA C CA 1 ATOM 3812 C C . ALA C 1 137 ? 75.795 33.536 17.970 1.00 30.49 ? 138 ALA C C 1 ATOM 3813 O O . ALA C 1 137 ? 76.576 34.493 18.033 1.00 28.77 ? 138 ALA C O 1 ATOM 3814 C CB . ALA C 1 137 ? 74.231 33.321 19.899 1.00 29.16 ? 138 ALA C CB 1 ATOM 3815 N N . VAL C 1 138 ? 75.253 33.101 16.826 1.00 26.79 ? 139 VAL C N 1 ATOM 3816 C CA . VAL C 1 138 ? 75.495 33.740 15.530 1.00 25.62 ? 139 VAL C CA 1 ATOM 3817 C C . VAL C 1 138 ? 74.172 34.138 14.929 1.00 27.90 ? 139 VAL C C 1 ATOM 3818 O O . VAL C 1 138 ? 73.200 33.387 14.983 1.00 26.76 ? 139 VAL C O 1 ATOM 3819 C CB . VAL C 1 138 ? 76.342 32.840 14.572 1.00 29.18 ? 139 VAL C CB 1 ATOM 3820 C CG1 . VAL C 1 138 ? 76.611 33.506 13.212 1.00 28.14 ? 139 VAL C CG1 1 ATOM 3821 C CG2 . VAL C 1 138 ? 77.645 32.430 15.227 1.00 28.83 ? 139 VAL C CG2 1 ATOM 3822 N N . CYS C 1 139 ? 74.149 35.338 14.353 1.00 27.06 ? 140 CYS C N 1 ATOM 3823 C CA . CYS C 1 139 ? 72.998 35.910 13.647 1.00 27.23 ? 140 CYS C CA 1 ATOM 3824 C C . CYS C 1 139 ? 73.508 36.449 12.339 1.00 30.30 ? 140 CYS C C 1 ATOM 3825 O O . CYS C 1 139 ? 74.463 37.219 12.344 1.00 31.17 ? 140 CYS C O 1 ATOM 3826 C CB . CYS C 1 139 ? 72.355 37.010 14.477 1.00 27.29 ? 140 CYS C CB 1 ATOM 3827 S SG . CYS C 1 139 ? 70.690 37.423 13.954 1.00 32.22 ? 140 CYS C SG 1 ATOM 3828 N N . GLU C 1 140 ? 72.918 36.022 11.226 1.00 26.85 ? 141 GLU C N 1 ATOM 3829 C CA . GLU C 1 140 ? 73.326 36.476 9.892 1.00 27.81 ? 141 GLU C CA 1 ATOM 3830 C C . GLU C 1 140 ? 72.139 36.976 9.109 1.00 30.84 ? 141 GLU C C 1 ATOM 3831 O O . GLU C 1 140 ? 71.070 36.380 9.163 1.00 29.38 ? 141 GLU C O 1 ATOM 3832 C CB . GLU C 1 140 ? 74.044 35.381 9.086 1.00 30.06 ? 141 GLU C CB 1 ATOM 3833 C CG . GLU C 1 140 ? 75.228 34.746 9.810 1.00 47.64 ? 141 GLU C CG 1 ATOM 3834 C CD . GLU C 1 140 ? 75.924 33.571 9.142 1.00 69.47 ? 141 GLU C CD 1 ATOM 3835 O OE1 . GLU C 1 140 ? 75.350 32.992 8.192 1.00 65.13 ? 141 GLU C OE1 1 ATOM 3836 O OE2 . GLU C 1 140 ? 77.021 33.190 9.615 1.00 69.61 ? 141 GLU C OE2 1 ATOM 3837 N N . ALA C 1 141 ? 72.337 38.078 8.381 1.00 27.72 ? 142 ALA C N 1 ATOM 3838 C CA . ALA C 1 141 ? 71.356 38.707 7.502 1.00 26.63 ? 142 ALA C CA 1 ATOM 3839 C C . ALA C 1 141 ? 72.051 38.799 6.114 1.00 29.43 ? 142 ALA C C 1 ATOM 3840 O O . ALA C 1 141 ? 72.860 39.673 5.861 1.00 27.66 ? 142 ALA C O 1 ATOM 3841 C CB . ALA C 1 141 ? 71.010 40.083 8.036 1.00 26.10 ? 142 ALA C CB 1 ATOM 3842 N N . MET C 1 142 ? 71.735 37.865 5.264 1.00 28.31 ? 143 MET C N 1 ATOM 3843 C CA . MET C 1 142 ? 72.371 37.667 3.979 1.00 29.89 ? 143 MET C CA 1 ATOM 3844 C C . MET C 1 142 ? 71.839 38.436 2.829 1.00 29.43 ? 143 MET C C 1 ATOM 3845 O O . MET C 1 142 ? 70.627 38.480 2.581 1.00 26.99 ? 143 MET C O 1 ATOM 3846 C CB . MET C 1 142 ? 72.445 36.179 3.677 1.00 34.58 ? 143 MET C CB 1 ATOM 3847 C CG . MET C 1 142 ? 73.192 35.422 4.777 1.00 42.58 ? 143 MET C CG 1 ATOM 3848 S SD . MET C 1 142 ? 73.662 33.793 4.248 1.00 52.72 ? 143 MET C SD 1 ATOM 3849 C CE . MET C 1 142 ? 75.057 34.182 3.069 1.00 48.73 ? 143 MET C CE 1 ATOM 3850 N N . ALA C 1 143 ? 72.767 39.104 2.154 1.00 27.35 ? 144 ALA C N 1 ATOM 3851 C CA . ALA C 1 143 ? 72.533 39.858 0.928 1.00 27.89 ? 144 ALA C CA 1 ATOM 3852 C C . ALA C 1 143 ? 71.226 40.699 0.907 1.00 29.38 ? 144 ALA C C 1 ATOM 3853 O O . ALA C 1 143 ? 70.336 40.462 0.102 1.00 29.47 ? 144 ALA C O 1 ATOM 3854 C CB . ALA C 1 143 ? 72.620 38.916 -0.281 1.00 28.09 ? 144 ALA C CB 1 ATOM 3855 N N . GLY C 1 144 ? 71.119 41.643 1.823 1.00 24.17 ? 145 GLY C N 1 ATOM 3856 C CA . GLY C 1 144 ? 69.995 42.570 1.871 1.00 22.58 ? 145 GLY C CA 1 ATOM 3857 C C . GLY C 1 144 ? 70.361 43.890 1.216 1.00 26.98 ? 145 GLY C C 1 ATOM 3858 O O . GLY C 1 144 ? 71.539 44.242 1.048 1.00 22.89 ? 145 GLY C O 1 ATOM 3859 N N . LYS C 1 145 ? 69.356 44.629 0.812 1.00 25.85 ? 146 LYS C N 1 ATOM 3860 C CA . LYS C 1 145 ? 69.574 45.937 0.221 1.00 24.81 ? 146 LYS C CA 1 ATOM 3861 C C . LYS C 1 145 ? 68.447 46.870 0.695 1.00 26.68 ? 146 LYS C C 1 ATOM 3862 O O . LYS C 1 145 ? 67.273 46.658 0.343 1.00 25.49 ? 146 LYS C O 1 ATOM 3863 C CB . LYS C 1 145 ? 69.645 45.868 -1.312 1.00 28.70 ? 146 LYS C CB 1 ATOM 3864 C CG . LYS C 1 145 ? 70.103 47.170 -1.953 1.00 26.83 ? 146 LYS C CG 1 ATOM 3865 C CD . LYS C 1 145 ? 70.114 47.103 -3.484 1.00 33.97 ? 146 LYS C CD 1 ATOM 3866 C CE . LYS C 1 145 ? 70.389 48.476 -4.112 1.00 29.22 ? 146 LYS C CE 1 ATOM 3867 N NZ . LYS C 1 145 ? 69.259 49.435 -3.863 1.00 42.05 ? 146 LYS C NZ 1 ATOM 3868 N N . PRO C 1 146 ? 68.759 47.901 1.520 1.00 21.55 ? 147 PRO C N 1 ATOM 3869 C CA . PRO C 1 146 ? 70.077 48.249 2.108 1.00 20.71 ? 147 PRO C CA 1 ATOM 3870 C C . PRO C 1 146 ? 70.525 47.222 3.146 1.00 27.00 ? 147 PRO C C 1 ATOM 3871 O O . PRO C 1 146 ? 69.786 46.289 3.426 1.00 27.91 ? 147 PRO C O 1 ATOM 3872 C CB . PRO C 1 146 ? 69.811 49.607 2.780 1.00 21.31 ? 147 PRO C CB 1 ATOM 3873 C CG . PRO C 1 146 ? 68.370 49.667 3.043 1.00 24.68 ? 147 PRO C CG 1 ATOM 3874 C CD . PRO C 1 146 ? 67.700 48.832 1.959 1.00 21.40 ? 147 PRO C CD 1 ATOM 3875 N N . ALA C 1 147 ? 71.716 47.385 3.725 1.00 23.95 ? 148 ALA C N 1 ATOM 3876 C CA . ALA C 1 147 ? 72.211 46.493 4.767 1.00 25.01 ? 148 ALA C CA 1 ATOM 3877 C C . ALA C 1 147 ? 71.231 46.429 5.939 1.00 29.21 ? 148 ALA C C 1 ATOM 3878 O O . ALA C 1 147 ? 70.715 47.462 6.375 1.00 29.45 ? 148 ALA C O 1 ATOM 3879 C CB . ALA C 1 147 ? 73.542 47.016 5.290 1.00 26.20 ? 148 ALA C CB 1 ATOM 3880 N N . ALA C 1 148 ? 70.983 45.225 6.452 1.00 24.18 ? 149 ALA C N 1 ATOM 3881 C CA . ALA C 1 148 ? 70.163 45.044 7.639 1.00 22.11 ? 149 ALA C CA 1 ATOM 3882 C C . ALA C 1 148 ? 70.967 45.478 8.857 1.00 25.69 ? 149 ALA C C 1 ATOM 3883 O O . ALA C 1 148 ? 72.189 45.639 8.776 1.00 26.28 ? 149 ALA C O 1 ATOM 3884 C CB . ALA C 1 148 ? 69.781 43.588 7.777 1.00 21.65 ? 149 ALA C CB 1 ATOM 3885 N N . GLN C 1 149 ? 70.296 45.715 9.979 1.00 22.68 ? 150 GLN C N 1 ATOM 3886 C CA . GLN C 1 149 ? 71.010 46.034 11.241 1.00 21.33 ? 150 GLN C CA 1 ATOM 3887 C C . GLN C 1 149 ? 70.713 44.917 12.229 1.00 26.83 ? 150 GLN C C 1 ATOM 3888 O O . GLN C 1 149 ? 69.553 44.498 12.393 1.00 26.38 ? 150 GLN C O 1 ATOM 3889 C CB . GLN C 1 149 ? 70.635 47.389 11.838 1.00 20.43 ? 150 GLN C CB 1 ATOM 3890 C CG . GLN C 1 149 ? 71.120 48.563 11.045 1.00 38.67 ? 150 GLN C CG 1 ATOM 3891 C CD . GLN C 1 149 ? 70.531 49.833 11.586 1.00 70.29 ? 150 GLN C CD 1 ATOM 3892 O OE1 . GLN C 1 149 ? 69.355 50.135 11.349 1.00 71.59 ? 150 GLN C OE1 1 ATOM 3893 N NE2 . GLN C 1 149 ? 71.326 50.591 12.333 1.00 64.51 ? 150 GLN C NE2 1 ATOM 3894 N N . ILE C 1 150 ? 71.766 44.438 12.878 1.00 25.96 ? 151 ILE C N 1 ATOM 3895 C CA . ILE C 1 150 ? 71.663 43.359 13.858 1.00 26.10 ? 151 ILE C CA 1 ATOM 3896 C C . ILE C 1 150 ? 71.853 43.889 15.282 1.00 31.82 ? 151 ILE C C 1 ATOM 3897 O O . ILE C 1 150 ? 72.838 44.573 15.572 1.00 30.70 ? 151 ILE C O 1 ATOM 3898 C CB . ILE C 1 150 ? 72.609 42.182 13.526 1.00 26.41 ? 151 ILE C CB 1 ATOM 3899 C CG1 . ILE C 1 150 ? 72.143 41.462 12.244 1.00 25.17 ? 151 ILE C CG1 1 ATOM 3900 C CG2 . ILE C 1 150 ? 72.715 41.237 14.713 1.00 25.71 ? 151 ILE C CG2 1 ATOM 3901 C CD1 . ILE C 1 150 ? 73.051 40.314 11.719 1.00 27.19 ? 151 ILE C CD1 1 ATOM 3902 N N . SER C 1 151 ? 70.901 43.569 16.158 1.00 28.32 ? 152 SER C N 1 ATOM 3903 C CA . SER C 1 151 ? 70.999 43.945 17.566 1.00 27.45 ? 152 SER C CA 1 ATOM 3904 C C . SER C 1 151 ? 70.611 42.770 18.445 1.00 30.99 ? 152 SER C C 1 ATOM 3905 O O . SER C 1 151 ? 69.728 41.970 18.082 1.00 28.74 ? 152 SER C O 1 ATOM 3906 C CB . SER C 1 151 ? 70.193 45.208 17.882 1.00 26.61 ? 152 SER C CB 1 ATOM 3907 O OG . SER C 1 151 ? 68.826 45.054 17.573 1.00 27.35 ? 152 SER C OG 1 ATOM 3908 N N . TRP C 1 152 ? 71.329 42.638 19.565 1.00 28.26 ? 153 TRP C N 1 ATOM 3909 C CA . TRP C 1 152 ? 71.157 41.527 20.502 1.00 28.93 ? 153 TRP C CA 1 ATOM 3910 C C . TRP C 1 152 ? 70.563 41.937 21.851 1.00 34.16 ? 153 TRP C C 1 ATOM 3911 O O . TRP C 1 152 ? 70.840 43.025 22.358 1.00 32.87 ? 153 TRP C O 1 ATOM 3912 C CB . TRP C 1 152 ? 72.525 40.878 20.781 1.00 26.89 ? 153 TRP C CB 1 ATOM 3913 C CG . TRP C 1 152 ? 73.135 40.200 19.603 1.00 27.10 ? 153 TRP C CG 1 ATOM 3914 C CD1 . TRP C 1 152 ? 74.042 40.728 18.731 1.00 29.52 ? 153 TRP C CD1 1 ATOM 3915 C CD2 . TRP C 1 152 ? 72.972 38.820 19.235 1.00 26.51 ? 153 TRP C CD2 1 ATOM 3916 N NE1 . TRP C 1 152 ? 74.436 39.772 17.825 1.00 28.69 ? 153 TRP C NE1 1 ATOM 3917 C CE2 . TRP C 1 152 ? 73.795 38.588 18.110 1.00 29.36 ? 153 TRP C CE2 1 ATOM 3918 C CE3 . TRP C 1 152 ? 72.188 37.757 19.737 1.00 27.23 ? 153 TRP C CE3 1 ATOM 3919 C CZ2 . TRP C 1 152 ? 73.910 37.325 17.516 1.00 27.83 ? 153 TRP C CZ2 1 ATOM 3920 C CZ3 . TRP C 1 152 ? 72.269 36.517 19.117 1.00 28.65 ? 153 TRP C CZ3 1 ATOM 3921 C CH2 . TRP C 1 152 ? 73.121 36.311 18.023 1.00 29.03 ? 153 TRP C CH2 1 ATOM 3922 N N . THR C 1 153 ? 69.825 41.009 22.460 1.00 33.28 ? 154 THR C N 1 ATOM 3923 C CA . THR C 1 153 ? 69.268 41.115 23.808 1.00 33.61 ? 154 THR C CA 1 ATOM 3924 C C . THR C 1 153 ? 69.591 39.821 24.569 1.00 39.36 ? 154 THR C C 1 ATOM 3925 O O . THR C 1 153 ? 69.188 38.751 24.109 1.00 40.37 ? 154 THR C O 1 ATOM 3926 C CB . THR C 1 153 ? 67.771 41.350 23.810 1.00 37.00 ? 154 THR C CB 1 ATOM 3927 O OG1 . THR C 1 153 ? 67.472 42.416 22.935 1.00 45.60 ? 154 THR C OG1 1 ATOM 3928 C CG2 . THR C 1 153 ? 67.265 41.710 25.196 1.00 37.11 ? 154 THR C CG2 1 ATOM 3929 N N . PRO C 1 154 ? 70.260 39.880 25.741 1.00 36.08 ? 155 PRO C N 1 ATOM 3930 C CA . PRO C 1 154 ? 70.864 41.067 26.402 1.00 35.37 ? 155 PRO C CA 1 ATOM 3931 C C . PRO C 1 154 ? 72.162 41.494 25.717 1.00 41.53 ? 155 PRO C C 1 ATOM 3932 O O . PRO C 1 154 ? 72.552 40.876 24.740 1.00 42.25 ? 155 PRO C O 1 ATOM 3933 C CB . PRO C 1 154 ? 71.113 40.563 27.831 1.00 35.73 ? 155 PRO C CB 1 ATOM 3934 C CG . PRO C 1 154 ? 71.427 39.110 27.659 1.00 41.51 ? 155 PRO C CG 1 ATOM 3935 C CD . PRO C 1 154 ? 70.567 38.638 26.488 1.00 37.69 ? 155 PRO C CD 1 ATOM 3936 N N . ASP C 1 155 ? 72.836 42.517 26.234 1.00 40.30 ? 156 ASP C N 1 ATOM 3937 C CA . ASP C 1 155 ? 74.102 43.007 25.692 1.00 40.33 ? 156 ASP C CA 1 ATOM 3938 C C . ASP C 1 155 ? 75.204 41.959 25.832 1.00 42.63 ? 156 ASP C C 1 ATOM 3939 O O . ASP C 1 155 ? 75.438 41.437 26.927 1.00 43.55 ? 156 ASP C O 1 ATOM 3940 C CB . ASP C 1 155 ? 74.575 44.274 26.464 1.00 42.12 ? 156 ASP C CB 1 ATOM 3941 C CG . ASP C 1 155 ? 73.734 45.518 26.354 1.00 59.13 ? 156 ASP C CG 1 ATOM 3942 O OD1 . ASP C 1 155 ? 73.083 45.711 25.284 1.00 62.14 ? 156 ASP C OD1 1 ATOM 3943 O OD2 . ASP C 1 155 ? 73.777 46.346 27.307 1.00 62.32 ? 156 ASP C OD2 1 ATOM 3944 N N . GLY C 1 156 ? 75.935 41.734 24.758 1.00 36.65 ? 157 GLY C N 1 ATOM 3945 C CA . GLY C 1 156 ? 77.065 40.819 24.809 1.00 34.65 ? 157 GLY C CA 1 ATOM 3946 C C . GLY C 1 156 ? 78.299 41.449 24.232 1.00 36.24 ? 157 GLY C C 1 ATOM 3947 O O . GLY C 1 156 ? 78.295 42.629 23.882 1.00 36.03 ? 157 GLY C O 1 ATOM 3948 N N . ASP C 1 157 ? 79.363 40.666 24.148 1.00 34.18 ? 158 ASP C N 1 ATOM 3949 C CA . ASP C 1 157 ? 80.612 41.049 23.502 1.00 33.96 ? 158 ASP C CA 1 ATOM 3950 C C . ASP C 1 157 ? 80.533 40.456 22.100 1.00 37.67 ? 158 ASP C C 1 ATOM 3951 O O . ASP C 1 157 ? 80.585 39.231 21.928 1.00 36.11 ? 158 ASP C O 1 ATOM 3952 C CB . ASP C 1 157 ? 81.817 40.564 24.297 1.00 35.10 ? 158 ASP C CB 1 ATOM 3953 C CG . ASP C 1 157 ? 81.795 41.064 25.732 1.00 48.38 ? 158 ASP C CG 1 ATOM 3954 O OD1 . ASP C 1 157 ? 81.667 42.279 25.933 1.00 45.26 ? 158 ASP C OD1 1 ATOM 3955 O OD2 . ASP C 1 157 ? 81.829 40.222 26.654 1.00 65.79 ? 158 ASP C OD2 1 ATOM 3956 N N . CYS C 1 158 ? 80.281 41.333 21.120 1.00 35.54 ? 159 CYS C N 1 ATOM 3957 C CA . CYS C 1 158 ? 80.015 41.022 19.728 1.00 36.92 ? 159 CYS C CA 1 ATOM 3958 C C . CYS C 1 158 ? 81.027 41.515 18.755 1.00 37.62 ? 159 CYS C C 1 ATOM 3959 O O . CYS C 1 158 ? 81.658 42.552 18.956 1.00 36.93 ? 159 CYS C O 1 ATOM 3960 C CB . CYS C 1 158 ? 78.625 41.511 19.356 1.00 40.21 ? 159 CYS C CB 1 ATOM 3961 S SG . CYS C 1 158 ? 77.359 40.993 20.531 1.00 47.39 ? 159 CYS C SG 1 ATOM 3962 N N . VAL C 1 159 ? 81.159 40.748 17.675 1.00 32.72 ? 160 VAL C N 1 ATOM 3963 C CA . VAL C 1 159 ? 81.946 41.052 16.494 1.00 32.27 ? 160 VAL C CA 1 ATOM 3964 C C . VAL C 1 159 ? 80.966 40.955 15.314 1.00 34.05 ? 160 VAL C C 1 ATOM 3965 O O . VAL C 1 159 ? 80.421 39.883 15.049 1.00 33.20 ? 160 VAL C O 1 ATOM 3966 C CB . VAL C 1 159 ? 83.212 40.176 16.304 1.00 35.52 ? 160 VAL C CB 1 ATOM 3967 C CG1 . VAL C 1 159 ? 83.949 40.586 15.035 1.00 34.70 ? 160 VAL C CG1 1 ATOM 3968 C CG2 . VAL C 1 159 ? 84.130 40.300 17.506 1.00 35.04 ? 160 VAL C CG2 1 ATOM 3969 N N . THR C 1 160 ? 80.685 42.088 14.672 1.00 30.01 ? 161 THR C N 1 ATOM 3970 C CA . THR C 1 160 ? 79.767 42.153 13.538 1.00 28.72 ? 161 THR C CA 1 ATOM 3971 C C . THR C 1 160 ? 80.527 42.486 12.293 1.00 32.07 ? 161 THR C C 1 ATOM 3972 O O . THR C 1 160 ? 81.187 43.516 12.241 1.00 32.26 ? 161 THR C O 1 ATOM 3973 C CB . THR C 1 160 ? 78.583 43.055 13.826 1.00 26.05 ? 161 THR C CB 1 ATOM 3974 O OG1 . THR C 1 160 ? 77.975 42.583 15.034 1.00 25.48 ? 161 THR C OG1 1 ATOM 3975 C CG2 . THR C 1 160 ? 77.548 43.048 12.694 1.00 19.57 ? 161 THR C CG2 1 ATOM 3976 N N . LYS C 1 161 ? 80.449 41.598 11.292 1.00 27.48 ? 162 LYS C N 1 ATOM 3977 C CA . LYS C 1 161 ? 81.155 41.795 10.025 1.00 25.96 ? 162 LYS C CA 1 ATOM 3978 C C . LYS C 1 161 ? 80.183 42.044 8.899 1.00 29.73 ? 162 LYS C C 1 ATOM 3979 O O . LYS C 1 161 ? 79.222 41.289 8.722 1.00 29.97 ? 162 LYS C O 1 ATOM 3980 C CB . LYS C 1 161 ? 82.115 40.637 9.727 1.00 26.18 ? 162 LYS C CB 1 ATOM 3981 C CG . LYS C 1 161 ? 83.253 40.593 10.722 1.00 36.98 ? 162 LYS C CG 1 ATOM 3982 C CD . LYS C 1 161 ? 84.364 39.648 10.317 1.00 49.77 ? 162 LYS C CD 1 ATOM 3983 C CE . LYS C 1 161 ? 85.193 39.183 11.492 1.00 51.81 ? 162 LYS C CE 1 ATOM 3984 N NZ . LYS C 1 161 ? 86.590 38.890 11.082 1.00 70.55 ? 162 LYS C NZ 1 ATOM 3985 N N . SER C 1 162 ? 80.377 43.160 8.177 1.00 25.54 ? 163 SER C N 1 ATOM 3986 C CA . SER C 1 162 ? 79.513 43.469 7.060 1.00 24.25 ? 163 SER C CA 1 ATOM 3987 C C . SER C 1 162 ? 80.347 43.399 5.784 1.00 28.52 ? 163 SER C C 1 ATOM 3988 O O . SER C 1 162 ? 81.504 43.824 5.769 1.00 27.68 ? 163 SER C O 1 ATOM 3989 C CB . SER C 1 162 ? 78.795 44.800 7.246 1.00 26.51 ? 163 SER C CB 1 ATOM 3990 O OG . SER C 1 162 ? 79.611 45.875 6.828 1.00 49.90 ? 163 SER C OG 1 ATOM 3991 N N . GLU C 1 163 ? 79.799 42.757 4.756 1.00 24.99 ? 164 GLU C N 1 ATOM 3992 C CA . GLU C 1 163 ? 80.504 42.567 3.510 1.00 24.84 ? 164 GLU C CA 1 ATOM 3993 C C . GLU C 1 163 ? 79.659 43.139 2.398 1.00 29.13 ? 164 GLU C C 1 ATOM 3994 O O . GLU C 1 163 ? 78.537 42.697 2.194 1.00 30.45 ? 164 GLU C O 1 ATOM 3995 C CB . GLU C 1 163 ? 80.792 41.075 3.314 1.00 26.21 ? 164 GLU C CB 1 ATOM 3996 C CG . GLU C 1 163 ? 81.637 40.754 2.092 1.00 39.64 ? 164 GLU C CG 1 ATOM 3997 C CD . GLU C 1 163 ? 81.660 39.307 1.624 1.00 70.21 ? 164 GLU C CD 1 ATOM 3998 O OE1 . GLU C 1 163 ? 81.157 38.402 2.338 1.00 59.06 ? 164 GLU C OE1 1 ATOM 3999 O OE2 . GLU C 1 163 ? 82.191 39.087 0.512 1.00 70.74 ? 164 GLU C OE2 1 ATOM 4000 N N . SER C 1 164 ? 80.171 44.157 1.725 1.00 26.70 ? 165 SER C N 1 ATOM 4001 C CA . SER C 1 164 ? 79.499 44.785 0.593 1.00 27.78 ? 165 SER C CA 1 ATOM 4002 C C . SER C 1 164 ? 79.755 43.950 -0.633 1.00 31.10 ? 165 SER C C 1 ATOM 4003 O O . SER C 1 164 ? 80.893 43.547 -0.853 1.00 33.01 ? 165 SER C O 1 ATOM 4004 C CB . SER C 1 164 ? 80.067 46.173 0.361 1.00 33.70 ? 165 SER C CB 1 ATOM 4005 O OG . SER C 1 164 ? 79.069 47.102 0.730 1.00 54.37 ? 165 SER C OG 1 ATOM 4006 N N . HIS C 1 165 ? 78.711 43.649 -1.401 1.00 25.28 ? 166 HIS C N 1 ATOM 4007 C CA . HIS C 1 165 ? 78.834 42.865 -2.618 1.00 24.16 ? 166 HIS C CA 1 ATOM 4008 C C . HIS C 1 165 ? 78.701 43.796 -3.791 1.00 28.72 ? 166 HIS C C 1 ATOM 4009 O O . HIS C 1 165 ? 77.973 44.788 -3.715 1.00 28.92 ? 166 HIS C O 1 ATOM 4010 C CB . HIS C 1 165 ? 77.770 41.752 -2.679 1.00 24.72 ? 166 HIS C CB 1 ATOM 4011 C CG . HIS C 1 165 ? 77.694 40.901 -1.446 1.00 26.76 ? 166 HIS C CG 1 ATOM 4012 N ND1 . HIS C 1 165 ? 78.763 40.084 -1.076 1.00 27.38 ? 166 HIS C ND1 1 ATOM 4013 C CD2 . HIS C 1 165 ? 76.681 40.743 -0.549 1.00 25.01 ? 166 HIS C CD2 1 ATOM 4014 C CE1 . HIS C 1 165 ? 78.374 39.479 0.039 1.00 24.39 ? 166 HIS C CE1 1 ATOM 4015 N NE2 . HIS C 1 165 ? 77.123 39.830 0.385 1.00 23.95 ? 166 HIS C NE2 1 ATOM 4016 N N . SER C 1 166 ? 79.375 43.476 -4.914 1.00 27.00 ? 167 SER C N 1 ATOM 4017 C CA . SER C 1 166 ? 79.317 44.304 -6.135 1.00 24.45 ? 167 SER C CA 1 ATOM 4018 C C . SER C 1 166 ? 77.934 44.417 -6.770 1.00 30.13 ? 167 SER C C 1 ATOM 4019 O O . SER C 1 166 ? 77.700 45.396 -7.480 1.00 34.43 ? 167 SER C O 1 ATOM 4020 C CB . SER C 1 166 ? 80.424 43.949 -7.120 1.00 25.63 ? 167 SER C CB 1 ATOM 4021 O OG . SER C 1 166 ? 80.175 42.733 -7.800 1.00 35.55 ? 167 SER C OG 1 ATOM 4022 N N . ASN C 1 167 ? 76.984 43.494 -6.460 1.00 25.65 ? 168 ASN C N 1 ATOM 4023 C CA . ASN C 1 167 ? 75.577 43.616 -6.900 1.00 25.46 ? 168 ASN C CA 1 ATOM 4024 C C . ASN C 1 167 ? 74.756 44.679 -6.108 1.00 29.89 ? 168 ASN C C 1 ATOM 4025 O O . ASN C 1 167 ? 73.625 44.951 -6.465 1.00 33.02 ? 168 ASN C O 1 ATOM 4026 C CB . ASN C 1 167 ? 74.852 42.259 -6.907 1.00 21.34 ? 168 ASN C CB 1 ATOM 4027 C CG . ASN C 1 167 ? 74.735 41.552 -5.584 1.00 39.93 ? 168 ASN C CG 1 ATOM 4028 O OD1 . ASN C 1 167 ? 74.965 42.116 -4.505 1.00 27.92 ? 168 ASN C OD1 1 ATOM 4029 N ND2 . ASN C 1 167 ? 74.330 40.287 -5.673 1.00 27.51 ? 168 ASN C ND2 1 ATOM 4030 N N . GLY C 1 168 ? 75.328 45.264 -5.062 1.00 25.78 ? 169 GLY C N 1 ATOM 4031 C CA . GLY C 1 168 ? 74.647 46.295 -4.280 1.00 26.67 ? 169 GLY C CA 1 ATOM 4032 C C . GLY C 1 168 ? 74.012 45.834 -2.977 1.00 32.58 ? 169 GLY C C 1 ATOM 4033 O O . GLY C 1 168 ? 73.411 46.636 -2.255 1.00 33.34 ? 169 GLY C O 1 ATOM 4034 N N . THR C 1 169 ? 74.094 44.541 -2.691 1.00 27.65 ? 170 THR C N 1 ATOM 4035 C CA . THR C 1 169 ? 73.585 43.980 -1.465 1.00 25.60 ? 170 THR C CA 1 ATOM 4036 C C . THR C 1 169 ? 74.721 43.964 -0.395 1.00 29.70 ? 170 THR C C 1 ATOM 4037 O O . THR C 1 169 ? 75.890 44.214 -0.713 1.00 29.20 ? 170 THR C O 1 ATOM 4038 C CB . THR C 1 169 ? 72.941 42.614 -1.709 1.00 24.64 ? 170 THR C CB 1 ATOM 4039 O OG1 . THR C 1 169 ? 73.965 41.645 -1.955 1.00 30.51 ? 170 THR C OG1 1 ATOM 4040 C CG2 . THR C 1 169 ? 71.856 42.633 -2.784 1.00 15.73 ? 170 THR C CG2 1 ATOM 4041 N N . VAL C 1 170 ? 74.360 43.699 0.876 1.00 25.30 ? 171 VAL C N 1 ATOM 4042 C CA . VAL C 1 170 ? 75.302 43.638 1.995 1.00 24.17 ? 171 VAL C CA 1 ATOM 4043 C C . VAL C 1 170 ? 74.924 42.463 2.859 1.00 28.96 ? 171 VAL C C 1 ATOM 4044 O O . VAL C 1 170 ? 73.756 42.320 3.244 1.00 28.31 ? 171 VAL C O 1 ATOM 4045 C CB . VAL C 1 170 ? 75.324 44.973 2.857 1.00 26.75 ? 171 VAL C CB 1 ATOM 4046 C CG1 . VAL C 1 170 ? 76.357 44.905 3.986 1.00 24.45 ? 171 VAL C CG1 1 ATOM 4047 C CG2 . VAL C 1 170 ? 75.532 46.230 1.973 1.00 26.00 ? 171 VAL C CG2 1 ATOM 4048 N N . THR C 1 171 ? 75.917 41.623 3.177 1.00 25.87 ? 172 THR C N 1 ATOM 4049 C CA . THR C 1 171 ? 75.773 40.510 4.100 1.00 24.75 ? 172 THR C CA 1 ATOM 4050 C C . THR C 1 171 ? 76.302 40.971 5.429 1.00 27.26 ? 172 THR C C 1 ATOM 4051 O O . THR C 1 171 ? 77.432 41.429 5.496 1.00 27.54 ? 172 THR C O 1 ATOM 4052 C CB . THR C 1 171 ? 76.514 39.259 3.577 1.00 28.23 ? 172 THR C CB 1 ATOM 4053 O OG1 . THR C 1 171 ? 75.769 38.757 2.469 1.00 25.96 ? 172 THR C OG1 1 ATOM 4054 C CG2 . THR C 1 171 ? 76.607 38.142 4.617 1.00 21.71 ? 172 THR C CG2 1 ATOM 4055 N N . VAL C 1 172 ? 75.504 40.844 6.479 1.00 25.82 ? 173 VAL C N 1 ATOM 4056 C CA . VAL C 1 172 ? 75.902 41.194 7.860 1.00 25.92 ? 173 VAL C CA 1 ATOM 4057 C C . VAL C 1 172 ? 75.897 39.899 8.692 1.00 27.94 ? 173 VAL C C 1 ATOM 4058 O O . VAL C 1 172 ? 74.917 39.165 8.650 1.00 25.26 ? 173 VAL C O 1 ATOM 4059 C CB . VAL C 1 172 ? 75.019 42.317 8.490 1.00 30.10 ? 173 VAL C CB 1 ATOM 4060 C CG1 . VAL C 1 172 ? 75.613 42.781 9.806 1.00 30.97 ? 173 VAL C CG1 1 ATOM 4061 C CG2 . VAL C 1 172 ? 74.845 43.507 7.545 1.00 29.32 ? 173 VAL C CG2 1 ATOM 4062 N N . ARG C 1 173 ? 77.023 39.584 9.366 1.00 26.57 ? 174 ARG C N 1 ATOM 4063 C CA . ARG C 1 173 ? 77.196 38.392 10.214 1.00 27.13 ? 174 ARG C CA 1 ATOM 4064 C C . ARG C 1 173 ? 77.661 38.821 11.602 1.00 29.26 ? 174 ARG C C 1 ATOM 4065 O O . ARG C 1 173 ? 78.715 39.452 11.737 1.00 28.17 ? 174 ARG C O 1 ATOM 4066 C CB . ARG C 1 173 ? 78.224 37.411 9.620 1.00 30.60 ? 174 ARG C CB 1 ATOM 4067 C CG . ARG C 1 173 ? 77.887 36.935 8.223 1.00 54.78 ? 174 ARG C CG 1 ATOM 4068 C CD . ARG C 1 173 ? 78.993 36.092 7.624 1.00 73.25 ? 174 ARG C CD 1 ATOM 4069 N NE . ARG C 1 173 ? 78.482 34.790 7.191 1.00 91.84 ? 174 ARG C NE 1 ATOM 4070 C CZ . ARG C 1 173 ? 78.377 34.397 5.923 1.00 110.42 ? 174 ARG C CZ 1 ATOM 4071 N NH1 . ARG C 1 173 ? 78.774 35.195 4.934 1.00 93.96 ? 174 ARG C NH1 1 ATOM 4072 N NH2 . ARG C 1 173 ? 77.902 33.193 5.636 1.00 102.08 ? 174 ARG C NH2 1 ATOM 4073 N N . SER C 1 174 ? 76.889 38.471 12.633 1.00 25.73 ? 175 SER C N 1 ATOM 4074 C CA . SER C 1 174 ? 77.208 38.848 14.018 1.00 24.90 ? 175 SER C CA 1 ATOM 4075 C C . SER C 1 174 ? 77.410 37.618 14.917 1.00 28.05 ? 175 SER C C 1 ATOM 4076 O O . SER C 1 174 ? 76.566 36.733 14.914 1.00 27.92 ? 175 SER C O 1 ATOM 4077 C CB . SER C 1 174 ? 76.118 39.761 14.592 1.00 24.18 ? 175 SER C CB 1 ATOM 4078 O OG . SER C 1 174 ? 76.541 40.303 15.832 1.00 28.81 ? 175 SER C OG 1 ATOM 4079 N N . THR C 1 175 ? 78.513 37.589 15.689 1.00 25.00 ? 176 THR C N 1 ATOM 4080 C CA . THR C 1 175 ? 78.865 36.536 16.640 1.00 26.17 ? 176 THR C CA 1 ATOM 4081 C C . THR C 1 175 ? 79.037 37.179 18.022 1.00 34.03 ? 176 THR C C 1 ATOM 4082 O O . THR C 1 175 ? 79.853 38.084 18.161 1.00 32.38 ? 176 THR C O 1 ATOM 4083 C CB . THR C 1 175 ? 80.157 35.794 16.206 1.00 35.64 ? 176 THR C CB 1 ATOM 4084 O OG1 . THR C 1 175 ? 79.996 35.307 14.882 1.00 41.59 ? 176 THR C OG1 1 ATOM 4085 C CG2 . THR C 1 175 ? 80.501 34.634 17.118 1.00 31.04 ? 176 THR C CG2 1 ATOM 4086 N N . CYS C 1 176 ? 78.249 36.740 19.026 1.00 34.82 ? 177 CYS C N 1 ATOM 4087 C CA . CYS C 1 176 ? 78.385 37.225 20.396 1.00 37.91 ? 177 CYS C CA 1 ATOM 4088 C C . CYS C 1 176 ? 78.758 36.188 21.367 1.00 39.49 ? 177 CYS C C 1 ATOM 4089 O O . CYS C 1 176 ? 78.505 35.011 21.171 1.00 35.77 ? 177 CYS C O 1 ATOM 4090 C CB . CYS C 1 176 ? 77.151 37.955 20.889 1.00 41.07 ? 177 CYS C CB 1 ATOM 4091 S SG . CYS C 1 176 ? 76.609 39.245 19.798 1.00 47.55 ? 177 CYS C SG 1 ATOM 4092 N N . HIS C 1 177 ? 79.212 36.676 22.502 1.00 38.98 ? 178 HIS C N 1 ATOM 4093 C CA . HIS C 1 177 ? 79.511 35.892 23.674 1.00 39.73 ? 178 HIS C CA 1 ATOM 4094 C C . HIS C 1 177 ? 78.960 36.657 24.857 1.00 40.76 ? 178 HIS C C 1 ATOM 4095 O O . HIS C 1 177 ? 79.081 37.890 24.916 1.00 37.16 ? 178 HIS C O 1 ATOM 4096 C CB . HIS C 1 177 ? 81.018 35.714 23.827 1.00 41.60 ? 178 HIS C CB 1 ATOM 4097 C CG . HIS C 1 177 ? 81.388 34.979 25.071 1.00 46.95 ? 178 HIS C CG 1 ATOM 4098 N ND1 . HIS C 1 177 ? 81.250 33.597 25.162 1.00 49.72 ? 178 HIS C ND1 1 ATOM 4099 C CD2 . HIS C 1 177 ? 81.892 35.450 26.242 1.00 49.57 ? 178 HIS C CD2 1 ATOM 4100 C CE1 . HIS C 1 177 ? 81.667 33.272 26.382 1.00 49.46 ? 178 HIS C CE1 1 ATOM 4101 N NE2 . HIS C 1 177 ? 82.068 34.351 27.070 1.00 49.61 ? 178 HIS C NE2 1 ATOM 4102 N N . TRP C 1 178 ? 78.374 35.928 25.800 1.00 38.04 ? 179 TRP C N 1 ATOM 4103 C CA . TRP C 1 178 ? 77.853 36.504 27.034 1.00 38.33 ? 179 TRP C CA 1 ATOM 4104 C C . TRP C 1 178 ? 78.658 35.918 28.189 1.00 51.61 ? 179 TRP C C 1 ATOM 4105 O O . TRP C 1 178 ? 78.776 34.693 28.301 1.00 51.19 ? 179 TRP C O 1 ATOM 4106 C CB . TRP C 1 178 ? 76.352 36.235 27.167 1.00 34.94 ? 179 TRP C CB 1 ATOM 4107 C CG . TRP C 1 178 ? 75.541 36.989 26.162 1.00 34.54 ? 179 TRP C CG 1 ATOM 4108 C CD1 . TRP C 1 178 ? 74.913 38.185 26.345 1.00 36.92 ? 179 TRP C CD1 1 ATOM 4109 C CD2 . TRP C 1 178 ? 75.300 36.612 24.797 1.00 33.77 ? 179 TRP C CD2 1 ATOM 4110 N NE1 . TRP C 1 178 ? 74.282 38.570 25.184 1.00 36.01 ? 179 TRP C NE1 1 ATOM 4111 C CE2 . TRP C 1 178 ? 74.525 37.638 24.210 1.00 37.11 ? 179 TRP C CE2 1 ATOM 4112 C CE3 . TRP C 1 178 ? 75.682 35.515 24.009 1.00 34.32 ? 179 TRP C CE3 1 ATOM 4113 C CZ2 . TRP C 1 178 ? 74.096 37.586 22.881 1.00 35.79 ? 179 TRP C CZ2 1 ATOM 4114 C CZ3 . TRP C 1 178 ? 75.281 35.474 22.690 1.00 35.35 ? 179 TRP C CZ3 1 ATOM 4115 C CH2 . TRP C 1 178 ? 74.486 36.493 22.139 1.00 35.97 ? 179 TRP C CH2 1 ATOM 4116 N N . GLU C 1 179 ? 79.322 36.776 28.964 1.00 55.90 ? 180 GLU C N 1 ATOM 4117 C CA . GLU C 1 179 ? 80.114 36.262 30.071 1.00 60.02 ? 180 GLU C CA 1 ATOM 4118 C C . GLU C 1 179 ? 79.184 35.828 31.218 1.00 71.34 ? 180 GLU C C 1 ATOM 4119 O O . GLU C 1 179 ? 79.257 34.669 31.653 1.00 71.30 ? 180 GLU C O 1 ATOM 4120 C CB . GLU C 1 179 ? 81.198 37.253 30.493 1.00 62.01 ? 180 GLU C CB 1 ATOM 4121 C CG . GLU C 1 179 ? 82.544 36.958 29.841 1.00 77.60 ? 180 GLU C CG 1 ATOM 4122 C CD . GLU C 1 179 ? 83.212 38.143 29.162 1.00 108.33 ? 180 GLU C CD 1 ATOM 4123 O OE1 . GLU C 1 179 ? 83.450 39.166 29.848 1.00 101.34 ? 180 GLU C OE1 1 ATOM 4124 O OE2 . GLU C 1 179 ? 83.507 38.045 27.947 1.00 104.64 ? 180 GLU C OE2 1 ATOM 4125 N N . GLN C 1 180 ? 78.231 36.724 31.601 1.00 72.48 ? 181 GLN C N 1 ATOM 4126 C CA . GLN C 1 180 ? 77.185 36.528 32.622 1.00 74.18 ? 181 GLN C CA 1 ATOM 4127 C C . GLN C 1 180 ? 76.547 35.133 32.507 1.00 79.21 ? 181 GLN C C 1 ATOM 4128 O O . GLN C 1 180 ? 75.814 34.877 31.542 1.00 79.11 ? 181 GLN C O 1 ATOM 4129 C CB . GLN C 1 180 ? 76.095 37.615 32.485 1.00 76.72 ? 181 GLN C CB 1 ATOM 4130 C CG . GLN C 1 180 ? 76.504 39.011 32.980 1.00 112.13 ? 181 GLN C CG 1 ATOM 4131 C CD . GLN C 1 180 ? 75.348 39.844 33.518 1.00 145.92 ? 181 GLN C CD 1 ATOM 4132 O OE1 . GLN C 1 180 ? 74.245 39.347 33.803 1.00 144.30 ? 181 GLN C OE1 1 ATOM 4133 N NE2 . GLN C 1 180 ? 75.594 41.137 33.716 1.00 139.45 ? 181 GLN C NE2 1 ATOM 4134 N N . ASN C 1 181 ? 76.846 34.228 33.484 1.00 75.38 ? 182 ASN C N 1 ATOM 4135 C CA . ASN C 1 181 ? 76.340 32.849 33.491 1.00 74.31 ? 182 ASN C CA 1 ATOM 4136 C C . ASN C 1 181 ? 74.819 32.663 33.687 1.00 74.33 ? 182 ASN C C 1 ATOM 4137 O O . ASN C 1 181 ? 74.273 31.621 33.277 1.00 73.56 ? 182 ASN C O 1 ATOM 4138 C CB . ASN C 1 181 ? 77.201 31.918 34.337 1.00 77.56 ? 182 ASN C CB 1 ATOM 4139 C CG . ASN C 1 181 ? 78.434 31.443 33.599 1.00 106.65 ? 182 ASN C CG 1 ATOM 4140 O OD1 . ASN C 1 181 ? 79.426 32.166 33.471 1.00 101.53 ? 182 ASN C OD1 1 ATOM 4141 N ND2 . ASN C 1 181 ? 78.390 30.220 33.075 1.00 98.74 ? 182 ASN C ND2 1 ATOM 4142 N N . ASN C 1 182 ? 74.129 33.710 34.218 1.00 67.31 ? 183 ASN C N 1 ATOM 4143 C CA . ASN C 1 182 ? 72.664 33.750 34.389 1.00 65.87 ? 183 ASN C CA 1 ATOM 4144 C C . ASN C 1 182 ? 71.877 33.761 33.035 1.00 64.76 ? 183 ASN C C 1 ATOM 4145 O O . ASN C 1 182 ? 70.661 33.521 33.027 1.00 64.67 ? 183 ASN C O 1 ATOM 4146 C CB . ASN C 1 182 ? 72.275 34.977 35.221 1.00 68.36 ? 183 ASN C CB 1 ATOM 4147 C CG . ASN C 1 182 ? 72.961 36.250 34.772 1.00 97.89 ? 183 ASN C CG 1 ATOM 4148 O OD1 . ASN C 1 182 ? 74.200 36.362 34.804 1.00 91.20 ? 183 ASN C OD1 1 ATOM 4149 N ND2 . ASN C 1 182 ? 72.173 37.238 34.349 1.00 89.36 ? 183 ASN C ND2 1 ATOM 4150 N N . VAL C 1 183 ? 72.583 34.100 31.921 1.00 55.88 ? 184 VAL C N 1 ATOM 4151 C CA . VAL C 1 183 ? 72.048 34.232 30.563 1.00 52.03 ? 184 VAL C CA 1 ATOM 4152 C C . VAL C 1 183 ? 72.043 32.868 29.876 1.00 48.68 ? 184 VAL C C 1 ATOM 4153 O O . VAL C 1 183 ? 73.109 32.307 29.652 1.00 47.61 ? 184 VAL C O 1 ATOM 4154 C CB . VAL C 1 183 ? 72.858 35.287 29.751 1.00 54.68 ? 184 VAL C CB 1 ATOM 4155 C CG1 . VAL C 1 183 ? 72.268 35.480 28.361 1.00 53.73 ? 184 VAL C CG1 1 ATOM 4156 C CG2 . VAL C 1 183 ? 72.948 36.622 30.491 1.00 54.16 ? 184 VAL C CG2 1 ATOM 4157 N N . SER C 1 184 ? 70.860 32.350 29.519 1.00 40.68 ? 185 SER C N 1 ATOM 4158 C CA . SER C 1 184 ? 70.775 31.054 28.839 1.00 39.90 ? 185 SER C CA 1 ATOM 4159 C C . SER C 1 184 ? 70.156 31.159 27.440 1.00 40.92 ? 185 SER C C 1 ATOM 4160 O O . SER C 1 184 ? 70.459 30.353 26.570 1.00 41.19 ? 185 SER C O 1 ATOM 4161 C CB . SER C 1 184 ? 70.015 30.029 29.690 1.00 42.67 ? 185 SER C CB 1 ATOM 4162 O OG . SER C 1 184 ? 68.814 30.551 30.231 1.00 50.33 ? 185 SER C OG 1 ATOM 4163 N N . VAL C 1 185 ? 69.254 32.126 27.260 1.00 34.20 ? 186 VAL C N 1 ATOM 4164 C CA . VAL C 1 185 ? 68.545 32.390 26.010 1.00 32.98 ? 186 VAL C CA 1 ATOM 4165 C C . VAL C 1 185 ? 68.807 33.836 25.581 1.00 36.63 ? 186 VAL C C 1 ATOM 4166 O O . VAL C 1 185 ? 68.709 34.764 26.379 1.00 38.02 ? 186 VAL C O 1 ATOM 4167 C CB . VAL C 1 185 ? 67.031 32.041 26.082 1.00 34.22 ? 186 VAL C CB 1 ATOM 4168 C CG1 . VAL C 1 185 ? 66.342 32.245 24.739 1.00 33.19 ? 186 VAL C CG1 1 ATOM 4169 C CG2 . VAL C 1 185 ? 66.844 30.599 26.512 1.00 33.58 ? 186 VAL C CG2 1 ATOM 4170 N N . VAL C 1 186 ? 69.219 33.998 24.333 1.00 30.50 ? 187 VAL C N 1 ATOM 4171 C CA . VAL C 1 186 ? 69.528 35.302 23.728 1.00 26.90 ? 187 VAL C CA 1 ATOM 4172 C C . VAL C 1 186 ? 68.603 35.552 22.562 1.00 27.79 ? 187 VAL C C 1 ATOM 4173 O O . VAL C 1 186 ? 68.057 34.605 21.959 1.00 23.97 ? 187 VAL C O 1 ATOM 4174 C CB . VAL C 1 186 ? 71.027 35.486 23.358 1.00 26.81 ? 187 VAL C CB 1 ATOM 4175 C CG1 . VAL C 1 186 ? 71.906 35.362 24.598 1.00 26.32 ? 187 VAL C CG1 1 ATOM 4176 C CG2 . VAL C 1 186 ? 71.455 34.503 22.273 1.00 25.41 ? 187 VAL C CG2 1 ATOM 4177 N N . SER C 1 187 ? 68.415 36.842 22.251 1.00 24.89 ? 188 SER C N 1 ATOM 4178 C CA A SER C 1 187 ? 67.536 37.228 21.158 0.70 25.09 ? 188 SER C CA 1 ATOM 4179 C CA B SER C 1 187 ? 67.532 37.238 21.168 0.30 23.84 ? 188 SER C CA 1 ATOM 4180 C C . SER C 1 187 ? 68.238 38.095 20.140 1.00 27.22 ? 188 SER C C 1 ATOM 4181 O O . SER C 1 187 ? 68.983 39.008 20.499 1.00 27.12 ? 188 SER C O 1 ATOM 4182 C CB A SER C 1 187 ? 66.275 37.899 21.696 0.70 30.09 ? 188 SER C CB 1 ATOM 4183 C CB B SER C 1 187 ? 66.304 37.947 21.727 0.30 25.32 ? 188 SER C CB 1 ATOM 4184 O OG A SER C 1 187 ? 65.280 37.987 20.687 0.70 45.62 ? 188 SER C OG 1 ATOM 4185 O OG B SER C 1 187 ? 65.630 37.103 22.644 0.30 27.41 ? 188 SER C OG 1 ATOM 4186 N N . CYS C 1 188 ? 68.037 37.786 18.871 1.00 25.37 ? 189 CYS C N 1 ATOM 4187 C CA . CYS C 1 188 ? 68.635 38.564 17.774 1.00 26.24 ? 189 CYS C CA 1 ATOM 4188 C C . CYS C 1 188 ? 67.547 39.220 16.984 1.00 29.25 ? 189 CYS C C 1 ATOM 4189 O O . CYS C 1 188 ? 66.647 38.524 16.486 1.00 27.17 ? 189 CYS C O 1 ATOM 4190 C CB . CYS C 1 188 ? 69.539 37.741 16.854 1.00 27.54 ? 189 CYS C CB 1 ATOM 4191 S SG . CYS C 1 188 ? 70.155 38.702 15.430 1.00 32.07 ? 189 CYS C SG 1 ATOM 4192 N N . LEU C 1 189 ? 67.652 40.551 16.822 1.00 26.45 ? 190 LEU C N 1 ATOM 4193 C CA . LEU C 1 189 ? 66.747 41.315 15.957 1.00 26.25 ? 190 LEU C CA 1 ATOM 4194 C C . LEU C 1 189 ? 67.490 41.737 14.690 1.00 28.75 ? 190 LEU C C 1 ATOM 4195 O O . LEU C 1 189 ? 68.554 42.373 14.762 1.00 29.23 ? 190 LEU C O 1 ATOM 4196 C CB . LEU C 1 189 ? 66.157 42.541 16.689 1.00 25.89 ? 190 LEU C CB 1 ATOM 4197 C CG . LEU C 1 189 ? 65.371 43.581 15.847 1.00 27.59 ? 190 LEU C CG 1 ATOM 4198 C CD1 . LEU C 1 189 ? 64.019 43.040 15.372 1.00 23.42 ? 190 LEU C CD1 1 ATOM 4199 C CD2 . LEU C 1 189 ? 65.218 44.888 16.617 1.00 25.68 ? 190 LEU C CD2 1 ATOM 4200 N N . VAL C 1 190 ? 66.944 41.346 13.543 1.00 24.89 ? 191 VAL C N 1 ATOM 4201 C CA . VAL C 1 190 ? 67.459 41.751 12.233 1.00 24.17 ? 191 VAL C CA 1 ATOM 4202 C C . VAL C 1 190 ? 66.476 42.824 11.710 1.00 25.92 ? 191 VAL C C 1 ATOM 4203 O O . VAL C 1 190 ? 65.382 42.488 11.246 1.00 22.81 ? 191 VAL C O 1 ATOM 4204 C CB . VAL C 1 190 ? 67.607 40.567 11.227 1.00 27.11 ? 191 VAL C CB 1 ATOM 4205 C CG1 . VAL C 1 190 ? 68.006 41.074 9.839 1.00 25.76 ? 191 VAL C CG1 1 ATOM 4206 C CG2 . VAL C 1 190 ? 68.596 39.529 11.737 1.00 26.22 ? 191 VAL C CG2 1 ATOM 4207 N N . SER C 1 191 ? 66.863 44.104 11.820 1.00 22.24 ? 192 SER C N 1 ATOM 4208 C CA . SER C 1 191 ? 66.012 45.194 11.329 1.00 22.78 ? 192 SER C CA 1 ATOM 4209 C C . SER C 1 191 ? 66.248 45.461 9.824 1.00 24.87 ? 192 SER C C 1 ATOM 4210 O O . SER C 1 191 ? 67.387 45.547 9.362 1.00 22.22 ? 192 SER C O 1 ATOM 4211 C CB . SER C 1 191 ? 66.290 46.489 12.095 1.00 27.13 ? 192 SER C CB 1 ATOM 4212 O OG . SER C 1 191 ? 66.121 46.290 13.488 1.00 46.39 ? 192 SER C OG 1 ATOM 4213 N N . HIS C 1 192 ? 65.168 45.721 9.103 1.00 22.37 ? 193 HIS C N 1 ATOM 4214 C CA . HIS C 1 192 ? 65.248 46.094 7.699 1.00 22.92 ? 193 HIS C CA 1 ATOM 4215 C C . HIS C 1 192 ? 63.986 46.838 7.296 1.00 31.17 ? 193 HIS C C 1 ATOM 4216 O O . HIS C 1 192 ? 62.912 46.477 7.764 1.00 32.60 ? 193 HIS C O 1 ATOM 4217 C CB . HIS C 1 192 ? 65.455 44.838 6.819 1.00 21.56 ? 193 HIS C CB 1 ATOM 4218 C CG . HIS C 1 192 ? 65.987 45.151 5.471 1.00 23.34 ? 193 HIS C CG 1 ATOM 4219 N ND1 . HIS C 1 192 ? 65.176 45.155 4.353 1.00 25.43 ? 193 HIS C ND1 1 ATOM 4220 C CD2 . HIS C 1 192 ? 67.250 45.453 5.100 1.00 24.32 ? 193 HIS C CD2 1 ATOM 4221 C CE1 . HIS C 1 192 ? 65.968 45.475 3.334 1.00 24.50 ? 193 HIS C CE1 1 ATOM 4222 N NE2 . HIS C 1 192 ? 67.232 45.664 3.750 1.00 24.07 ? 193 HIS C NE2 1 ATOM 4223 N N . SER C 1 193 ? 64.092 47.824 6.392 1.00 30.34 ? 194 SER C N 1 ATOM 4224 C CA . SER C 1 193 ? 62.926 48.574 5.868 1.00 30.93 ? 194 SER C CA 1 ATOM 4225 C C . SER C 1 193 ? 61.841 47.673 5.275 1.00 33.82 ? 194 SER C C 1 ATOM 4226 O O . SER C 1 193 ? 60.682 48.046 5.338 1.00 35.73 ? 194 SER C O 1 ATOM 4227 C CB . SER C 1 193 ? 63.345 49.627 4.837 1.00 35.73 ? 194 SER C CB 1 ATOM 4228 O OG . SER C 1 193 ? 64.079 49.097 3.743 1.00 45.47 ? 194 SER C OG 1 ATOM 4229 N N . THR C 1 194 ? 62.188 46.472 4.768 1.00 28.93 ? 195 THR C N 1 ATOM 4230 C CA . THR C 1 194 ? 61.220 45.537 4.153 1.00 27.99 ? 195 THR C CA 1 ATOM 4231 C C . THR C 1 194 ? 60.519 44.667 5.193 1.00 33.68 ? 195 THR C C 1 ATOM 4232 O O . THR C 1 194 ? 59.663 43.877 4.817 1.00 36.07 ? 195 THR C O 1 ATOM 4233 C CB . THR C 1 194 ? 61.914 44.648 3.100 1.00 29.63 ? 195 THR C CB 1 ATOM 4234 O OG1 . THR C 1 194 ? 62.954 43.943 3.753 1.00 27.98 ? 195 THR C OG1 1 ATOM 4235 C CG2 . THR C 1 194 ? 62.461 45.433 1.858 1.00 19.57 ? 195 THR C CG2 1 ATOM 4236 N N . GLY C 1 195 ? 60.908 44.792 6.476 1.00 28.96 ? 196 GLY C N 1 ATOM 4237 C CA . GLY C 1 195 ? 60.373 44.011 7.586 1.00 27.20 ? 196 GLY C CA 1 ATOM 4238 C C . GLY C 1 195 ? 61.438 43.464 8.519 1.00 32.96 ? 196 GLY C C 1 ATOM 4239 O O . GLY C 1 195 ? 62.480 42.956 8.088 1.00 33.49 ? 196 GLY C O 1 ATOM 4240 N N . ASN C 1 196 ? 61.170 43.571 9.816 1.00 30.78 ? 197 ASN C N 1 ATOM 4241 C CA . ASN C 1 196 ? 62.032 43.103 10.908 1.00 29.57 ? 197 ASN C CA 1 ATOM 4242 C C . ASN C 1 196 ? 61.849 41.605 11.141 1.00 32.16 ? 197 ASN C C 1 ATOM 4243 O O . ASN C 1 196 ? 60.783 41.081 10.872 1.00 31.52 ? 197 ASN C O 1 ATOM 4244 C CB . ASN C 1 196 ? 61.717 43.882 12.174 1.00 26.83 ? 197 ASN C CB 1 ATOM 4245 C CG . ASN C 1 196 ? 62.173 45.295 12.135 1.00 41.07 ? 197 ASN C CG 1 ATOM 4246 O OD1 . ASN C 1 196 ? 62.766 45.723 11.147 1.00 33.85 ? 197 ASN C OD1 1 ATOM 4247 N ND2 . ASN C 1 196 ? 61.912 46.041 13.213 1.00 57.45 ? 197 ASN C ND2 1 ATOM 4248 N N . GLN C 1 197 ? 62.905 40.907 11.572 1.00 28.44 ? 198 GLN C N 1 ATOM 4249 C CA . GLN C 1 197 ? 62.882 39.455 11.827 1.00 28.70 ? 198 GLN C CA 1 ATOM 4250 C C . GLN C 1 197 ? 63.671 39.219 13.102 1.00 31.63 ? 198 GLN C C 1 ATOM 4251 O O . GLN C 1 197 ? 64.771 39.761 13.260 1.00 30.39 ? 198 GLN C O 1 ATOM 4252 C CB . GLN C 1 197 ? 63.546 38.654 10.675 1.00 30.02 ? 198 GLN C CB 1 ATOM 4253 C CG . GLN C 1 197 ? 62.748 38.702 9.368 1.00 37.40 ? 198 GLN C CG 1 ATOM 4254 C CD . GLN C 1 197 ? 63.554 38.241 8.197 1.00 42.66 ? 198 GLN C CD 1 ATOM 4255 O OE1 . GLN C 1 197 ? 64.342 38.998 7.609 1.00 41.19 ? 198 GLN C OE1 1 ATOM 4256 N NE2 . GLN C 1 197 ? 63.336 36.997 7.808 1.00 27.12 ? 198 GLN C NE2 1 ATOM 4257 N N . SER C 1 198 ? 63.116 38.443 14.021 1.00 27.80 ? 199 SER C N 1 ATOM 4258 C CA . SER C 1 198 ? 63.820 38.132 15.269 1.00 26.55 ? 199 SER C CA 1 ATOM 4259 C C . SER C 1 198 ? 63.549 36.725 15.715 1.00 29.98 ? 199 SER C C 1 ATOM 4260 O O . SER C 1 198 ? 62.507 36.152 15.369 1.00 30.63 ? 199 SER C O 1 ATOM 4261 C CB . SER C 1 198 ? 63.491 39.142 16.363 1.00 28.79 ? 199 SER C CB 1 ATOM 4262 O OG . SER C 1 198 ? 62.131 39.029 16.740 1.00 38.86 ? 199 SER C OG 1 ATOM 4263 N N . LEU C 1 199 ? 64.517 36.135 16.424 1.00 24.86 ? 200 LEU C N 1 ATOM 4264 C CA . LEU C 1 199 ? 64.403 34.774 16.925 1.00 23.73 ? 200 LEU C CA 1 ATOM 4265 C C . LEU C 1 199 ? 65.303 34.632 18.121 1.00 26.57 ? 200 LEU C C 1 ATOM 4266 O O . LEU C 1 199 ? 66.331 35.313 18.194 1.00 24.97 ? 200 LEU C O 1 ATOM 4267 C CB . LEU C 1 199 ? 64.803 33.772 15.827 1.00 23.59 ? 200 LEU C CB 1 ATOM 4268 C CG . LEU C 1 199 ? 64.244 32.345 15.902 1.00 28.46 ? 200 LEU C CG 1 ATOM 4269 C CD1 . LEU C 1 199 ? 62.700 32.334 15.868 1.00 29.83 ? 200 LEU C CD1 1 ATOM 4270 C CD2 . LEU C 1 199 ? 64.733 31.526 14.725 1.00 26.45 ? 200 LEU C CD2 1 ATOM 4271 N N . SER C 1 200 ? 64.908 33.754 19.067 1.00 23.82 ? 201 SER C N 1 ATOM 4272 C CA . SER C 1 200 ? 65.714 33.469 20.247 1.00 24.47 ? 201 SER C CA 1 ATOM 4273 C C . SER C 1 200 ? 66.614 32.224 20.036 1.00 26.84 ? 201 SER C C 1 ATOM 4274 O O . SER C 1 200 ? 66.244 31.295 19.335 1.00 26.51 ? 201 SER C O 1 ATOM 4275 C CB . SER C 1 200 ? 64.845 33.350 21.491 1.00 27.18 ? 201 SER C CB 1 ATOM 4276 O OG . SER C 1 200 ? 64.262 34.590 21.839 1.00 34.43 ? 201 SER C OG 1 ATOM 4277 N N . ILE C 1 201 ? 67.799 32.248 20.626 1.00 24.09 ? 202 ILE C N 1 ATOM 4278 C CA . ILE C 1 201 ? 68.806 31.196 20.549 1.00 25.23 ? 202 ILE C CA 1 ATOM 4279 C C . ILE C 1 201 ? 69.157 30.711 21.947 1.00 32.15 ? 202 ILE C C 1 ATOM 4280 O O . ILE C 1 201 ? 69.524 31.514 22.816 1.00 32.89 ? 202 ILE C O 1 ATOM 4281 C CB . ILE C 1 201 ? 70.094 31.670 19.792 1.00 28.51 ? 202 ILE C CB 1 ATOM 4282 C CG1 . ILE C 1 201 ? 69.776 32.330 18.426 1.00 29.84 ? 202 ILE C CG1 1 ATOM 4283 C CG2 . ILE C 1 201 ? 71.088 30.535 19.632 1.00 28.27 ? 202 ILE C CG2 1 ATOM 4284 C CD1 . ILE C 1 201 ? 70.900 33.162 17.831 1.00 25.63 ? 202 ILE C CD1 1 ATOM 4285 N N . GLU C 1 202 ? 69.083 29.389 22.154 1.00 31.10 ? 203 GLU C N 1 ATOM 4286 C CA . GLU C 1 202 ? 69.453 28.773 23.422 1.00 31.51 ? 203 GLU C CA 1 ATOM 4287 C C . GLU C 1 202 ? 70.962 28.552 23.418 1.00 33.33 ? 203 GLU C C 1 ATOM 4288 O O . GLU C 1 202 ? 71.483 27.861 22.552 1.00 32.06 ? 203 GLU C O 1 ATOM 4289 C CB . GLU C 1 202 ? 68.696 27.464 23.573 1.00 33.98 ? 203 GLU C CB 1 ATOM 4290 C CG . GLU C 1 202 ? 68.747 26.857 24.966 1.00 51.32 ? 203 GLU C CG 1 ATOM 4291 C CD . GLU C 1 202 ? 68.109 25.484 25.044 1.00 76.16 ? 203 GLU C CD 1 ATOM 4292 O OE1 . GLU C 1 202 ? 66.872 25.382 24.887 1.00 83.37 ? 203 GLU C OE1 1 ATOM 4293 O OE2 . GLU C 1 202 ? 68.859 24.500 25.212 1.00 80.70 ? 203 GLU C OE2 1 ATOM 4294 N N . LEU C 1 203 ? 71.675 29.199 24.330 1.00 31.25 ? 204 LEU C N 1 ATOM 4295 C CA . LEU C 1 203 ? 73.135 29.039 24.462 1.00 30.41 ? 204 LEU C CA 1 ATOM 4296 C C . LEU C 1 203 ? 73.488 27.611 24.941 1.00 38.59 ? 204 LEU C C 1 ATOM 4297 O O . LEU C 1 203 ? 72.712 27.003 25.687 1.00 38.31 ? 204 LEU C O 1 ATOM 4298 C CB . LEU C 1 203 ? 73.684 30.073 25.469 1.00 28.86 ? 204 LEU C CB 1 ATOM 4299 C CG . LEU C 1 203 ? 73.505 31.544 25.081 1.00 31.24 ? 204 LEU C CG 1 ATOM 4300 C CD1 . LEU C 1 203 ? 74.206 32.440 26.065 1.00 30.38 ? 204 LEU C CD1 1 ATOM 4301 C CD2 . LEU C 1 203 ? 74.009 31.820 23.670 1.00 29.71 ? 204 LEU C CD2 1 ATOM 4302 N N . SER C 1 204 ? 74.656 27.091 24.518 1.00 37.09 ? 205 SER C N 1 ATOM 4303 C CA . SER C 1 204 ? 75.183 25.756 24.880 1.00 52.97 ? 205 SER C CA 1 ATOM 4304 C C . SER C 1 204 ? 75.435 25.630 26.383 1.00 91.52 ? 205 SER C C 1 ATOM 4305 O O . SER C 1 204 ? 75.819 26.605 27.027 1.00 61.23 ? 205 SER C O 1 ATOM 4306 C CB . SER C 1 204 ? 76.479 25.468 24.130 1.00 56.50 ? 205 SER C CB 1 ATOM 4307 O OG . SER C 1 204 ? 77.572 26.232 24.626 1.00 65.06 ? 205 SER C OG 1 HETATM 4308 C C1 . NAG D 2 . ? 49.111 16.541 11.046 1.00 89.81 ? 690 NAG A C1 1 HETATM 4309 C C2 . NAG D 2 . ? 49.008 16.599 9.515 1.00 88.66 ? 690 NAG A C2 1 HETATM 4310 C C3 . NAG D 2 . ? 47.556 16.349 9.102 1.00 92.82 ? 690 NAG A C3 1 HETATM 4311 C C4 . NAG D 2 . ? 46.988 15.107 9.796 1.00 95.23 ? 690 NAG A C4 1 HETATM 4312 C C5 . NAG D 2 . ? 47.116 15.234 11.315 1.00 94.08 ? 690 NAG A C5 1 HETATM 4313 C C6 . NAG D 2 . ? 46.608 14.033 12.087 1.00 93.50 ? 690 NAG A C6 1 HETATM 4314 C C7 . NAG D 2 . ? 50.384 18.227 8.238 1.00 76.81 ? 690 NAG A C7 1 HETATM 4315 C C8 . NAG D 2 . ? 50.639 19.689 8.034 1.00 72.34 ? 690 NAG A C8 1 HETATM 4316 N N2 . NAG D 2 . ? 49.416 17.937 9.118 1.00 82.48 ? 690 NAG A N2 1 HETATM 4317 O O3 . NAG D 2 . ? 47.489 16.202 7.687 1.00 93.19 ? 690 NAG A O3 1 HETATM 4318 O O4 . NAG D 2 . ? 45.617 14.941 9.438 1.00 96.45 ? 690 NAG A O4 1 HETATM 4319 O O5 . NAG D 2 . ? 48.496 15.414 11.675 1.00 92.27 ? 690 NAG A O5 1 HETATM 4320 O O6 . NAG D 2 . ? 47.548 12.961 12.132 1.00 92.92 ? 690 NAG A O6 1 HETATM 4321 O O7 . NAG D 2 . ? 51.030 17.362 7.656 1.00 77.19 ? 690 NAG A O7 1 HETATM 4322 C C1 . NAG E 2 . ? 36.221 25.502 15.330 1.00 103.33 ? 770 NAG A C1 1 HETATM 4323 C C2 . NAG E 2 . ? 35.101 25.606 16.366 1.00 107.65 ? 770 NAG A C2 1 HETATM 4324 C C3 . NAG E 2 . ? 33.776 25.437 15.622 1.00 109.20 ? 770 NAG A C3 1 HETATM 4325 C C4 . NAG E 2 . ? 33.646 26.487 14.518 1.00 109.12 ? 770 NAG A C4 1 HETATM 4326 C C5 . NAG E 2 . ? 34.846 26.412 13.573 1.00 106.79 ? 770 NAG A C5 1 HETATM 4327 C C6 . NAG E 2 . ? 34.895 27.526 12.552 1.00 105.56 ? 770 NAG A C6 1 HETATM 4328 C C7 . NAG E 2 . ? 35.731 24.851 18.625 1.00 109.67 ? 770 NAG A C7 1 HETATM 4329 C C8 . NAG E 2 . ? 35.722 23.699 19.582 1.00 108.95 ? 770 NAG A C8 1 HETATM 4330 N N2 . NAG E 2 . ? 35.245 24.595 17.402 1.00 108.74 ? 770 NAG A N2 1 HETATM 4331 O O3 . NAG E 2 . ? 32.685 25.530 16.534 1.00 109.76 ? 770 NAG A O3 1 HETATM 4332 O O4 . NAG E 2 . ? 32.447 26.273 13.781 1.00 111.00 ? 770 NAG A O4 1 HETATM 4333 O O5 . NAG E 2 . ? 36.063 26.507 14.328 1.00 104.79 ? 770 NAG A O5 1 HETATM 4334 O O6 . NAG E 2 . ? 36.126 27.501 11.836 1.00 103.88 ? 770 NAG A O6 1 HETATM 4335 O O7 . NAG E 2 . ? 36.140 25.964 18.953 1.00 110.92 ? 770 NAG A O7 1 HETATM 4336 N N . CYS F 3 . ? 53.814 33.980 5.763 1.00 55.96 ? 1206 CYS A N 1 HETATM 4337 C CA . CYS F 3 . ? 54.588 34.264 6.990 1.00 52.38 ? 1206 CYS A CA 1 HETATM 4338 C C . CYS F 3 . ? 55.300 35.614 6.775 1.00 83.61 ? 1206 CYS A C 1 HETATM 4339 O O . CYS F 3 . ? 55.632 35.944 5.606 1.00 86.33 ? 1206 CYS A O 1 HETATM 4340 C CB . CYS F 3 . ? 55.604 33.153 7.247 1.00 50.92 ? 1206 CYS A CB 1 HETATM 4341 S SG . CYS F 3 . ? 55.490 32.343 8.874 1.00 53.27 ? 1206 CYS A SG 1 HETATM 4342 O OXT . CYS F 3 . ? 55.543 36.325 7.776 1.00 106.66 ? 1206 CYS A OXT 1 HETATM 4343 S S . SO4 G 4 . ? 29.576 35.277 35.375 1.00 87.27 ? 1207 SO4 A S 1 HETATM 4344 O O1 . SO4 G 4 . ? 29.559 36.692 35.809 1.00 88.67 ? 1207 SO4 A O1 1 HETATM 4345 O O2 . SO4 G 4 . ? 30.919 34.864 34.940 1.00 85.60 ? 1207 SO4 A O2 1 HETATM 4346 O O3 . SO4 G 4 . ? 28.614 35.091 34.286 1.00 84.87 ? 1207 SO4 A O3 1 HETATM 4347 O O4 . SO4 G 4 . ? 29.192 34.448 36.522 1.00 90.80 ? 1207 SO4 A O4 1 HETATM 4348 S S . SO4 H 4 . ? 57.137 27.589 2.037 1.00 145.62 ? 1208 SO4 A S 1 HETATM 4349 O O1 . SO4 H 4 . ? 57.589 28.883 2.549 1.00 145.20 ? 1208 SO4 A O1 1 HETATM 4350 O O2 . SO4 H 4 . ? 57.748 27.373 0.727 1.00 146.33 ? 1208 SO4 A O2 1 HETATM 4351 O O3 . SO4 H 4 . ? 55.670 27.585 1.922 1.00 144.78 ? 1208 SO4 A O3 1 HETATM 4352 O O4 . SO4 H 4 . ? 57.559 26.513 2.934 1.00 145.57 ? 1208 SO4 A O4 1 HETATM 4353 C C1 . NAG I 2 . ? 31.350 35.735 28.760 1.00 53.58 ? 1680 NAG A C1 1 HETATM 4354 C C2 . NAG I 2 . ? 30.634 35.270 27.491 1.00 55.08 ? 1680 NAG A C2 1 HETATM 4355 C C3 . NAG I 2 . ? 29.303 35.996 27.285 1.00 53.07 ? 1680 NAG A C3 1 HETATM 4356 C C4 . NAG I 2 . ? 28.474 36.032 28.563 1.00 55.92 ? 1680 NAG A C4 1 HETATM 4357 C C5 . NAG I 2 . ? 29.309 36.539 29.734 1.00 55.90 ? 1680 NAG A C5 1 HETATM 4358 C C6 . NAG I 2 . ? 28.576 36.489 31.053 1.00 56.94 ? 1680 NAG A C6 1 HETATM 4359 C C7 . NAG I 2 . ? 32.074 34.677 25.588 1.00 65.23 ? 1680 NAG A C7 1 HETATM 4360 C C8 . NAG I 2 . ? 32.830 35.220 24.411 1.00 61.54 ? 1680 NAG A C8 1 HETATM 4361 N N2 . NAG I 2 . ? 31.538 35.584 26.397 1.00 60.04 ? 1680 NAG A N2 1 HETATM 4362 O O3 . NAG I 2 . ? 28.577 35.327 26.263 1.00 50.60 ? 1680 NAG A O3 1 HETATM 4363 O O4 . NAG I 2 . ? 27.371 36.912 28.379 1.00 59.69 ? 1680 NAG A O4 1 HETATM 4364 O O5 . NAG I 2 . ? 30.467 35.707 29.878 1.00 55.87 ? 1680 NAG A O5 1 HETATM 4365 O O6 . NAG I 2 . ? 28.250 35.152 31.395 1.00 60.90 ? 1680 NAG A O6 1 HETATM 4366 O O7 . NAG I 2 . ? 31.959 33.468 25.792 1.00 70.84 ? 1680 NAG A O7 1 HETATM 4367 C C1 . NAG J 2 . ? 37.227 55.842 19.991 1.00 63.81 ? 1970 NAG A C1 1 HETATM 4368 C C2 . NAG J 2 . ? 38.313 56.382 19.057 1.00 73.18 ? 1970 NAG A C2 1 HETATM 4369 C C3 . NAG J 2 . ? 39.483 56.913 19.885 1.00 77.03 ? 1970 NAG A C3 1 HETATM 4370 C C4 . NAG J 2 . ? 39.001 57.917 20.931 1.00 78.29 ? 1970 NAG A C4 1 HETATM 4371 C C5 . NAG J 2 . ? 37.881 57.324 21.787 1.00 75.72 ? 1970 NAG A C5 1 HETATM 4372 C C6 . NAG J 2 . ? 37.253 58.310 22.752 1.00 77.57 ? 1970 NAG A C6 1 HETATM 4373 C C7 . NAG J 2 . ? 38.682 55.495 16.781 1.00 81.06 ? 1970 NAG A C7 1 HETATM 4374 C C8 . NAG J 2 . ? 39.295 54.385 15.980 1.00 80.62 ? 1970 NAG A C8 1 HETATM 4375 N N2 . NAG J 2 . ? 38.775 55.372 18.116 1.00 77.48 ? 1970 NAG A N2 1 HETATM 4376 O O3 . NAG J 2 . ? 40.422 57.546 19.019 1.00 78.98 ? 1970 NAG A O3 1 HETATM 4377 O O4 . NAG J 2 . ? 40.102 58.300 21.751 1.00 79.99 ? 1970 NAG A O4 1 HETATM 4378 O O5 . NAG J 2 . ? 36.825 56.838 20.941 1.00 70.22 ? 1970 NAG A O5 1 HETATM 4379 O O6 . NAG J 2 . ? 36.654 59.430 22.097 1.00 79.27 ? 1970 NAG A O6 1 HETATM 4380 O O7 . NAG J 2 . ? 38.131 56.456 16.245 1.00 83.59 ? 1970 NAG A O7 1 HETATM 4381 C C1 . NAG K 2 . ? 55.900 39.284 26.873 1.00 98.62 ? 2000 NAG A C1 1 HETATM 4382 C C2 . NAG K 2 . ? 55.697 38.713 28.279 1.00 100.27 ? 2000 NAG A C2 1 HETATM 4383 C C3 . NAG K 2 . ? 54.913 39.772 29.057 1.00 102.43 ? 2000 NAG A C3 1 HETATM 4384 C C4 . NAG K 2 . ? 55.656 41.108 29.058 1.00 103.77 ? 2000 NAG A C4 1 HETATM 4385 C C5 . NAG K 2 . ? 55.942 41.564 27.625 1.00 103.47 ? 2000 NAG A C5 1 HETATM 4386 C C6 . NAG K 2 . ? 56.811 42.799 27.533 1.00 104.31 ? 2000 NAG A C6 1 HETATM 4387 C C7 . NAG K 2 . ? 55.513 36.244 28.249 1.00 97.37 ? 2000 NAG A C7 1 HETATM 4388 C C8 . NAG K 2 . ? 54.568 35.087 28.120 1.00 96.97 ? 2000 NAG A C8 1 HETATM 4389 N N2 . NAG K 2 . ? 54.950 37.465 28.225 1.00 99.14 ? 2000 NAG A N2 1 HETATM 4390 O O3 . NAG K 2 . ? 54.694 39.334 30.394 1.00 102.56 ? 2000 NAG A O3 1 HETATM 4391 O O4 . NAG K 2 . ? 54.870 42.085 29.737 1.00 103.57 ? 2000 NAG A O4 1 HETATM 4392 O O5 . NAG K 2 . ? 56.622 40.521 26.904 1.00 101.23 ? 2000 NAG A O5 1 HETATM 4393 O O6 . NAG K 2 . ? 58.126 42.562 28.020 1.00 105.30 ? 2000 NAG A O6 1 HETATM 4394 O O7 . NAG K 2 . ? 56.726 36.082 28.356 1.00 97.01 ? 2000 NAG A O7 1 HETATM 4395 C C1 . NAG L 2 . ? 13.247 46.804 -1.195 1.00 102.39 ? 690 NAG B C1 1 HETATM 4396 C C2 . NAG L 2 . ? 13.716 45.344 -1.216 1.00 103.66 ? 690 NAG B C2 1 HETATM 4397 C C3 . NAG L 2 . ? 14.009 44.907 -2.654 1.00 108.07 ? 690 NAG B C3 1 HETATM 4398 C C4 . NAG L 2 . ? 12.890 45.325 -3.609 1.00 109.75 ? 690 NAG B C4 1 HETATM 4399 C C5 . NAG L 2 . ? 12.579 46.820 -3.489 1.00 107.71 ? 690 NAG B C5 1 HETATM 4400 C C6 . NAG L 2 . ? 11.442 47.283 -4.374 1.00 106.49 ? 690 NAG B C6 1 HETATM 4401 C C7 . NAG L 2 . ? 15.192 44.521 0.589 1.00 97.76 ? 690 NAG B C7 1 HETATM 4402 C C8 . NAG L 2 . ? 16.537 44.702 1.228 1.00 97.15 ? 690 NAG B C8 1 HETATM 4403 N N2 . NAG L 2 . ? 14.943 45.328 -0.437 1.00 99.84 ? 690 NAG B N2 1 HETATM 4404 O O3 . NAG L 2 . ? 14.193 43.493 -2.688 1.00 108.50 ? 690 NAG B O3 1 HETATM 4405 O O4 . NAG L 2 . ? 13.281 45.009 -4.946 1.00 110.18 ? 690 NAG B O4 1 HETATM 4406 O O5 . NAG L 2 . ? 12.222 47.145 -2.132 1.00 106.02 ? 690 NAG B O5 1 HETATM 4407 O O6 . NAG L 2 . ? 10.157 47.015 -3.812 1.00 106.32 ? 690 NAG B O6 1 HETATM 4408 O O7 . NAG L 2 . ? 14.373 43.700 0.992 1.00 98.01 ? 690 NAG B O7 1 HETATM 4409 C C1 . NAG M 2 . ? 24.416 54.199 -10.943 1.00 90.97 ? 770 NAG B C1 1 HETATM 4410 C C2 . NAG M 2 . ? 24.671 55.313 -11.960 1.00 95.82 ? 770 NAG B C2 1 HETATM 4411 C C3 . NAG M 2 . ? 25.167 54.681 -13.261 1.00 95.08 ? 770 NAG B C3 1 HETATM 4412 C C4 . NAG M 2 . ? 26.394 53.804 -13.007 1.00 94.40 ? 770 NAG B C4 1 HETATM 4413 C C5 . NAG M 2 . ? 26.095 52.765 -11.926 1.00 93.82 ? 770 NAG B C5 1 HETATM 4414 C C6 . NAG M 2 . ? 27.311 51.989 -11.473 1.00 95.33 ? 770 NAG B C6 1 HETATM 4415 C C7 . NAG M 2 . ? 23.193 57.263 -11.632 1.00 101.48 ? 770 NAG B C7 1 HETATM 4416 C C8 . NAG M 2 . ? 21.894 57.897 -12.025 1.00 101.79 ? 770 NAG B C8 1 HETATM 4417 N N2 . NAG M 2 . ? 23.450 56.069 -12.190 1.00 99.35 ? 770 NAG B N2 1 HETATM 4418 O O3 . NAG M 2 . ? 25.485 55.711 -14.192 1.00 94.65 ? 770 NAG B O3 1 HETATM 4419 O O4 . NAG M 2 . ? 26.756 53.128 -14.207 1.00 95.16 ? 770 NAG B O4 1 HETATM 4420 O O5 . NAG M 2 . ? 25.597 53.425 -10.755 1.00 92.16 ? 770 NAG B O5 1 HETATM 4421 O O6 . NAG M 2 . ? 27.069 51.317 -10.232 1.00 95.80 ? 770 NAG B O6 1 HETATM 4422 O O7 . NAG M 2 . ? 23.974 57.813 -10.859 1.00 102.42 ? 770 NAG B O7 1 HETATM 4423 N N . CYS N 3 . ? 28.889 45.169 8.763 1.00 61.29 ? 1206 CYS B N 1 HETATM 4424 C CA . CYS N 3 . ? 29.059 46.529 9.305 1.00 58.74 ? 1206 CYS B CA 1 HETATM 4425 C C . CYS N 3 . ? 30.424 46.659 10.003 1.00 89.09 ? 1206 CYS B C 1 HETATM 4426 O O . CYS N 3 . ? 30.599 46.087 11.111 1.00 87.25 ? 1206 CYS B O 1 HETATM 4427 C CB . CYS N 3 . ? 27.916 46.896 10.251 1.00 57.32 ? 1206 CYS B CB 1 HETATM 4428 S SG . CYS N 3 . ? 26.768 48.151 9.614 1.00 59.92 ? 1206 CYS B SG 1 HETATM 4429 O OXT . CYS N 3 . ? 31.316 47.327 9.427 1.00 115.43 ? 1206 CYS B OXT 1 HETATM 4430 S S . SO4 O 4 . ? 29.137 76.726 -14.308 1.00 102.63 ? 1207 SO4 B S 1 HETATM 4431 O O1 . SO4 O 4 . ? 28.860 75.977 -13.081 1.00 102.01 ? 1207 SO4 B O1 1 HETATM 4432 O O2 . SO4 O 4 . ? 30.153 77.768 -14.045 1.00 101.40 ? 1207 SO4 B O2 1 HETATM 4433 O O3 . SO4 O 4 . ? 27.884 77.338 -14.731 1.00 105.44 ? 1207 SO4 B O3 1 HETATM 4434 O O4 . SO4 O 4 . ? 29.601 75.839 -15.384 1.00 102.32 ? 1207 SO4 B O4 1 HETATM 4435 S S . SO4 P 4 . ? 17.309 47.948 -1.996 1.00 127.60 ? 1208 SO4 B S 1 HETATM 4436 O O1 . SO4 P 4 . ? 16.799 49.204 -1.398 1.00 125.69 ? 1208 SO4 B O1 1 HETATM 4437 O O2 . SO4 P 4 . ? 17.449 48.076 -3.456 1.00 129.22 ? 1208 SO4 B O2 1 HETATM 4438 O O3 . SO4 P 4 . ? 16.410 46.883 -1.748 1.00 127.69 ? 1208 SO4 B O3 1 HETATM 4439 O O4 . SO4 P 4 . ? 18.570 47.535 -1.392 1.00 128.06 ? 1208 SO4 B O4 1 HETATM 4440 S S . SO4 Q 4 . ? 23.488 40.312 10.393 1.00 165.80 ? 1209 SO4 B S 1 HETATM 4441 O O1 . SO4 Q 4 . ? 24.511 41.234 10.887 1.00 165.49 ? 1209 SO4 B O1 1 HETATM 4442 O O2 . SO4 Q 4 . ? 22.740 40.930 9.290 1.00 165.95 ? 1209 SO4 B O2 1 HETATM 4443 O O3 . SO4 Q 4 . ? 22.571 39.971 11.479 1.00 165.14 ? 1209 SO4 B O3 1 HETATM 4444 O O4 . SO4 Q 4 . ? 24.142 39.096 9.917 1.00 166.48 ? 1209 SO4 B O4 1 HETATM 4445 C C1 . NAG R 2 . ? 31.146 70.550 -12.566 1.00 48.92 ? 1680 NAG B C1 1 HETATM 4446 C C2 . NAG R 2 . ? 31.287 69.279 -13.407 1.00 52.37 ? 1680 NAG B C2 1 HETATM 4447 C C3 . NAG R 2 . ? 32.349 69.419 -14.498 1.00 53.21 ? 1680 NAG B C3 1 HETATM 4448 C C4 . NAG R 2 . ? 32.216 70.740 -15.253 1.00 54.12 ? 1680 NAG B C4 1 HETATM 4449 C C5 . NAG R 2 . ? 32.123 71.914 -14.285 1.00 55.00 ? 1680 NAG B C5 1 HETATM 4450 C C6 . NAG R 2 . ? 31.871 73.234 -14.975 1.00 60.75 ? 1680 NAG B C6 1 HETATM 4451 C C7 . NAG R 2 . ? 30.966 67.158 -12.212 1.00 56.32 ? 1680 NAG B C7 1 HETATM 4452 C C8 . NAG R 2 . ? 31.632 66.121 -11.357 1.00 49.15 ? 1680 NAG B C8 1 HETATM 4453 N N2 . NAG R 2 . ? 31.682 68.242 -12.466 1.00 54.00 ? 1680 NAG B N2 1 HETATM 4454 O O3 . NAG R 2 . ? 32.206 68.327 -15.399 1.00 51.43 ? 1680 NAG B O3 1 HETATM 4455 O O4 . NAG R 2 . ? 33.372 70.921 -16.060 1.00 57.03 ? 1680 NAG B O4 1 HETATM 4456 O O5 . NAG R 2 . ? 31.018 71.702 -13.399 1.00 54.12 ? 1680 NAG B O5 1 HETATM 4457 O O6 . NAG R 2 . ? 30.622 73.229 -15.653 1.00 65.21 ? 1680 NAG B O6 1 HETATM 4458 O O7 . NAG R 2 . ? 29.829 67.009 -12.653 1.00 63.71 ? 1680 NAG B O7 1 HETATM 4459 C C1 . NAG S 2 . ? 50.747 67.012 -1.848 1.00 65.94 ? 1970 NAG B C1 1 HETATM 4460 C C2 . NAG S 2 . ? 51.238 66.144 -0.686 1.00 73.24 ? 1970 NAG B C2 1 HETATM 4461 C C3 . NAG S 2 . ? 51.207 66.961 0.604 1.00 75.76 ? 1970 NAG B C3 1 HETATM 4462 C C4 . NAG S 2 . ? 51.978 68.269 0.436 1.00 76.76 ? 1970 NAG B C4 1 HETATM 4463 C C5 . NAG S 2 . ? 51.453 69.059 -0.766 1.00 71.87 ? 1970 NAG B C5 1 HETATM 4464 C C6 . NAG S 2 . ? 52.248 70.308 -1.084 1.00 73.34 ? 1970 NAG B C6 1 HETATM 4465 C C7 . NAG S 2 . ? 50.959 63.692 -0.651 1.00 80.94 ? 1970 NAG B C7 1 HETATM 4466 C C8 . NAG S 2 . ? 50.017 62.570 -0.334 1.00 80.05 ? 1970 NAG B C8 1 HETATM 4467 N N2 . NAG S 2 . ? 50.450 64.931 -0.536 1.00 77.54 ? 1970 NAG B N2 1 HETATM 4468 O O3 . NAG S 2 . ? 51.781 66.192 1.655 1.00 77.70 ? 1970 NAG B O3 1 HETATM 4469 O O4 . NAG S 2 . ? 51.859 69.035 1.633 1.00 80.65 ? 1970 NAG B O4 1 HETATM 4470 O O5 . NAG S 2 . ? 51.488 68.238 -1.945 1.00 67.09 ? 1970 NAG B O5 1 HETATM 4471 O O6 . NAG S 2 . ? 53.620 70.038 -1.386 1.00 74.92 ? 1970 NAG B O6 1 HETATM 4472 O O7 . NAG S 2 . ? 52.128 63.488 -0.984 1.00 82.29 ? 1970 NAG B O7 1 HETATM 4473 C C1 . NAG T 2 . ? 28.112 67.553 11.771 1.00 99.55 ? 2000 NAG B C1 1 HETATM 4474 C C2 . NAG T 2 . ? 27.260 68.768 11.402 1.00 101.05 ? 2000 NAG B C2 1 HETATM 4475 C C3 . NAG T 2 . ? 28.252 69.841 10.949 1.00 104.76 ? 2000 NAG B C3 1 HETATM 4476 C C4 . NAG T 2 . ? 29.259 70.154 12.055 1.00 105.83 ? 2000 NAG B C4 1 HETATM 4477 C C5 . NAG T 2 . ? 29.973 68.881 12.511 1.00 106.99 ? 2000 NAG B C5 1 HETATM 4478 C C6 . NAG T 2 . ? 30.843 69.068 13.736 1.00 109.07 ? 2000 NAG B C6 1 HETATM 4479 C C7 . NAG T 2 . ? 25.053 68.100 10.501 1.00 96.23 ? 2000 NAG B C7 1 HETATM 4480 C C8 . NAG T 2 . ? 24.302 67.727 9.259 1.00 96.17 ? 2000 NAG B C8 1 HETATM 4481 N N2 . NAG T 2 . ? 26.340 68.440 10.322 1.00 98.21 ? 2000 NAG B N2 1 HETATM 4482 O O3 . NAG T 2 . ? 27.556 71.022 10.569 1.00 106.96 ? 2000 NAG B O3 1 HETATM 4483 O O4 . NAG T 2 . ? 30.221 71.085 11.565 1.00 105.40 ? 2000 NAG B O4 1 HETATM 4484 O O5 . NAG T 2 . ? 29.008 67.866 12.839 1.00 103.83 ? 2000 NAG B O5 1 HETATM 4485 O O6 . NAG T 2 . ? 30.077 69.369 14.902 1.00 109.93 ? 2000 NAG B O6 1 HETATM 4486 O O7 . NAG T 2 . ? 24.525 68.082 11.609 1.00 95.34 ? 2000 NAG B O7 1 HETATM 4487 C C1 . NAG U 2 . ? 53.655 47.579 -30.182 1.00 72.23 ? 690 NAG C C1 1 HETATM 4488 C C2 . NAG U 2 . ? 52.308 47.174 -29.580 1.00 76.51 ? 690 NAG C C2 1 HETATM 4489 C C3 . NAG U 2 . ? 52.050 45.693 -29.870 1.00 79.65 ? 690 NAG C C3 1 HETATM 4490 C C4 . NAG U 2 . ? 52.171 45.434 -31.370 1.00 83.11 ? 690 NAG C C4 1 HETATM 4491 C C5 . NAG U 2 . ? 53.585 45.800 -31.815 1.00 79.79 ? 690 NAG C C5 1 HETATM 4492 C C6 . NAG U 2 . ? 53.859 45.593 -33.286 1.00 77.51 ? 690 NAG C C6 1 HETATM 4493 C C7 . NAG U 2 . ? 51.295 48.282 -27.631 1.00 76.95 ? 690 NAG C C7 1 HETATM 4494 C C8 . NAG U 2 . ? 51.453 48.658 -26.192 1.00 75.53 ? 690 NAG C C8 1 HETATM 4495 N N2 . NAG U 2 . ? 52.233 47.458 -28.154 1.00 76.18 ? 690 NAG C N2 1 HETATM 4496 O O3 . NAG U 2 . ? 50.780 45.265 -29.387 1.00 78.39 ? 690 NAG C O3 1 HETATM 4497 O O4 . NAG U 2 . ? 51.852 44.085 -31.688 1.00 88.03 ? 690 NAG C O4 1 HETATM 4498 O O5 . NAG U 2 . ? 53.812 47.193 -31.550 1.00 77.54 ? 690 NAG C O5 1 HETATM 4499 O O6 . NAG U 2 . ? 55.098 46.194 -33.627 1.00 74.86 ? 690 NAG C O6 1 HETATM 4500 O O7 . NAG U 2 . ? 50.340 48.691 -28.290 1.00 78.07 ? 690 NAG C O7 1 HETATM 4501 C C1 . NAG V 2 . ? 60.840 38.123 -17.119 1.00 77.12 ? 770 NAG C C1 1 HETATM 4502 C C2 . NAG V 2 . ? 62.038 37.186 -16.999 1.00 81.57 ? 770 NAG C C2 1 HETATM 4503 C C3 . NAG V 2 . ? 61.527 35.742 -17.061 1.00 83.27 ? 770 NAG C C3 1 HETATM 4504 C C4 . NAG V 2 . ? 60.387 35.501 -16.063 1.00 87.40 ? 770 NAG C C4 1 HETATM 4505 C C5 . NAG V 2 . ? 59.311 36.582 -16.166 1.00 86.40 ? 770 NAG C C5 1 HETATM 4506 C C6 . NAG V 2 . ? 58.272 36.540 -15.069 1.00 87.51 ? 770 NAG C C6 1 HETATM 4507 C C7 . NAG V 2 . ? 63.031 37.621 -19.288 1.00 87.33 ? 770 NAG C C7 1 HETATM 4508 C C8 . NAG V 2 . ? 64.320 37.767 -20.033 1.00 84.64 ? 770 NAG C C8 1 HETATM 4509 N N2 . NAG V 2 . ? 63.141 37.396 -17.932 1.00 84.99 ? 770 NAG C N2 1 HETATM 4510 O O3 . NAG V 2 . ? 62.607 34.857 -16.781 1.00 82.25 ? 770 NAG C O3 1 HETATM 4511 O O4 . NAG V 2 . ? 59.797 34.236 -16.338 1.00 90.85 ? 770 NAG C O4 1 HETATM 4512 O O5 . NAG V 2 . ? 59.933 37.866 -16.058 1.00 82.90 ? 770 NAG C O5 1 HETATM 4513 O O6 . NAG V 2 . ? 57.502 37.745 -15.045 1.00 85.93 ? 770 NAG C O6 1 HETATM 4514 O O7 . NAG V 2 . ? 61.948 37.689 -19.864 1.00 91.28 ? 770 NAG C O7 1 HETATM 4515 N N . CYS W 3 . ? 46.415 54.671 -12.986 1.00 56.01 ? 1206 CYS C N 1 HETATM 4516 C CA . CYS W 3 . ? 47.695 55.387 -13.122 1.00 51.81 ? 1206 CYS C CA 1 HETATM 4517 C C . CYS W 3 . ? 47.793 56.398 -11.940 1.00 93.47 ? 1206 CYS C C 1 HETATM 4518 O O . CYS W 3 . ? 48.602 56.168 -11.003 1.00 99.82 ? 1206 CYS C O 1 HETATM 4519 C CB . CYS W 3 . ? 47.758 56.085 -14.478 1.00 50.62 ? 1206 CYS C CB 1 HETATM 4520 S SG . CYS W 3 . ? 49.431 56.290 -15.193 1.00 53.22 ? 1206 CYS C SG 1 HETATM 4521 O OXT . CYS W 3 . ? 46.981 57.353 -11.892 1.00 115.70 ? 1206 CYS C OXT 1 HETATM 4522 S S . SO4 X 4 . ? 82.654 41.424 -5.212 1.00 82.08 ? 1207 SO4 C S 1 HETATM 4523 O O1 . SO4 X 4 . ? 83.619 42.527 -5.020 1.00 87.39 ? 1207 SO4 C O1 1 HETATM 4524 O O2 . SO4 X 4 . ? 82.356 41.262 -6.667 1.00 81.42 ? 1207 SO4 C O2 1 HETATM 4525 O O3 . SO4 X 4 . ? 81.444 41.709 -4.416 1.00 72.38 ? 1207 SO4 C O3 1 HETATM 4526 O O4 . SO4 X 4 . ? 83.319 40.204 -4.732 1.00 84.37 ? 1207 SO4 C O4 1 HETATM 4527 S S . SO4 Y 4 . ? 42.787 55.782 -20.673 1.00 134.37 ? 1208 SO4 C S 1 HETATM 4528 O O1 . SO4 Y 4 . ? 42.864 56.557 -19.426 1.00 134.00 ? 1208 SO4 C O1 1 HETATM 4529 O O2 . SO4 Y 4 . ? 44.073 55.785 -21.355 1.00 134.01 ? 1208 SO4 C O2 1 HETATM 4530 O O3 . SO4 Y 4 . ? 41.771 56.369 -21.547 1.00 134.10 ? 1208 SO4 C O3 1 HETATM 4531 O O4 . SO4 Y 4 . ? 42.437 54.392 -20.364 1.00 135.38 ? 1208 SO4 C O4 1 HETATM 4532 C C1 . GOL Z 5 . ? 60.464 41.862 -24.996 1.00 78.73 ? 1209 GOL C C1 1 HETATM 4533 O O1 . GOL Z 5 . ? 61.831 41.883 -25.375 1.00 74.15 ? 1209 GOL C O1 1 HETATM 4534 C C2 . GOL Z 5 . ? 59.707 43.021 -25.608 1.00 81.19 ? 1209 GOL C C2 1 HETATM 4535 O O2 . GOL Z 5 . ? 60.292 44.255 -25.190 1.00 80.42 ? 1209 GOL C O2 1 HETATM 4536 C C3 . GOL Z 5 . ? 58.248 43.003 -25.212 1.00 83.16 ? 1209 GOL C C3 1 HETATM 4537 O O3 . GOL Z 5 . ? 57.487 43.888 -26.029 1.00 84.45 ? 1209 GOL C O3 1 HETATM 4538 C C1 . GOL AA 5 . ? 50.656 66.476 -34.411 1.00 85.55 ? 1210 GOL C C1 1 HETATM 4539 O O1 . GOL AA 5 . ? 51.340 67.248 -33.426 1.00 82.17 ? 1210 GOL C O1 1 HETATM 4540 C C2 . GOL AA 5 . ? 49.153 66.571 -34.260 1.00 90.05 ? 1210 GOL C C2 1 HETATM 4541 O O2 . GOL AA 5 . ? 48.816 67.653 -33.385 1.00 93.44 ? 1210 GOL C O2 1 HETATM 4542 C C3 . GOL AA 5 . ? 48.534 65.283 -33.759 1.00 90.09 ? 1210 GOL C C3 1 HETATM 4543 O O3 . GOL AA 5 . ? 47.273 65.513 -33.135 1.00 88.63 ? 1210 GOL C O3 1 HETATM 4544 C C1 . GOL BA 5 . ? 70.720 44.008 28.805 1.00 71.52 ? 1211 GOL C C1 1 HETATM 4545 O O1 . GOL BA 5 . ? 72.052 44.141 29.280 1.00 69.14 ? 1211 GOL C O1 1 HETATM 4546 C C2 . GOL BA 5 . ? 70.482 44.931 27.634 1.00 75.32 ? 1211 GOL C C2 1 HETATM 4547 O O2 . GOL BA 5 . ? 70.304 46.275 28.101 1.00 81.28 ? 1211 GOL C O2 1 HETATM 4548 C C3 . GOL BA 5 . ? 69.330 44.530 26.741 1.00 72.70 ? 1211 GOL C C3 1 HETATM 4549 O O3 . GOL BA 5 . ? 69.559 44.978 25.408 1.00 70.24 ? 1211 GOL C O3 1 HETATM 4550 C C1 . NAG CA 2 . ? 74.171 39.434 -4.539 1.00 26.26 ? 1680 NAG C C1 1 HETATM 4551 C C2 . NAG CA 2 . ? 73.174 38.300 -4.807 1.00 25.38 ? 1680 NAG C C2 1 HETATM 4552 C C3 . NAG CA 2 . ? 73.198 37.261 -3.685 1.00 21.66 ? 1680 NAG C C3 1 HETATM 4553 C C4 . NAG CA 2 . ? 74.615 36.840 -3.333 1.00 25.97 ? 1680 NAG C C4 1 HETATM 4554 C C5 . NAG CA 2 . ? 75.505 38.060 -3.120 1.00 26.46 ? 1680 NAG C C5 1 HETATM 4555 C C6 . NAG CA 2 . ? 76.955 37.704 -2.885 1.00 23.14 ? 1680 NAG C C6 1 HETATM 4556 C C7 . NAG CA 2 . ? 71.099 38.912 -5.966 1.00 27.08 ? 1680 NAG C C7 1 HETATM 4557 C C8 . NAG CA 2 . ? 69.693 39.401 -5.768 1.00 22.92 ? 1680 NAG C C8 1 HETATM 4558 N N2 . NAG CA 2 . ? 71.853 38.900 -4.880 1.00 25.06 ? 1680 NAG C N2 1 HETATM 4559 O O3 . NAG CA 2 . ? 72.447 36.122 -4.081 1.00 23.63 ? 1680 NAG C O3 1 HETATM 4560 O O4 . NAG CA 2 . ? 74.593 36.104 -2.108 1.00 32.07 ? 1680 NAG C O4 1 HETATM 4561 O O5 . NAG CA 2 . ? 75.465 38.904 -4.283 1.00 24.41 ? 1680 NAG C O5 1 HETATM 4562 O O6 . NAG CA 2 . ? 77.486 37.030 -4.010 1.00 27.82 ? 1680 NAG C O6 1 HETATM 4563 O O7 . NAG CA 2 . ? 71.530 38.566 -7.070 1.00 29.22 ? 1680 NAG C O7 1 HETATM 4564 C C1 . NAG DA 2 . ? 62.317 47.412 13.325 1.00 62.34 ? 1970 NAG C C1 1 HETATM 4565 C C2 . NAG DA 2 . ? 61.135 48.363 13.534 1.00 73.63 ? 1970 NAG C C2 1 HETATM 4566 C C3 . NAG DA 2 . ? 61.696 49.783 13.637 1.00 75.10 ? 1970 NAG C C3 1 HETATM 4567 C C4 . NAG DA 2 . ? 62.735 49.879 14.755 1.00 74.85 ? 1970 NAG C C4 1 HETATM 4568 C C5 . NAG DA 2 . ? 63.830 48.826 14.568 1.00 70.28 ? 1970 NAG C C5 1 HETATM 4569 C C6 . NAG DA 2 . ? 64.816 48.742 15.714 1.00 70.41 ? 1970 NAG C C6 1 HETATM 4570 C C7 . NAG DA 2 . ? 58.881 47.912 12.629 1.00 87.13 ? 1970 NAG C C7 1 HETATM 4571 C C8 . NAG DA 2 . ? 57.994 48.048 11.427 1.00 86.92 ? 1970 NAG C C8 1 HETATM 4572 N N2 . NAG DA 2 . ? 60.161 48.286 12.455 1.00 82.13 ? 1970 NAG C N2 1 HETATM 4573 O O3 . NAG DA 2 . ? 60.636 50.707 13.862 1.00 75.48 ? 1970 NAG C O3 1 HETATM 4574 O O4 . NAG DA 2 . ? 63.329 51.176 14.727 1.00 76.38 ? 1970 NAG C O4 1 HETATM 4575 O O5 . NAG DA 2 . ? 63.251 47.518 14.409 1.00 64.72 ? 1970 NAG C O5 1 HETATM 4576 O O6 . NAG DA 2 . ? 64.209 48.311 16.927 1.00 70.85 ? 1970 NAG C O6 1 HETATM 4577 O O7 . NAG DA 2 . ? 58.461 47.485 13.705 1.00 89.18 ? 1970 NAG C O7 1 HETATM 4578 C C1 . NAG EA 2 . ? 65.896 62.754 -7.355 1.00 112.21 ? 2000 NAG C C1 1 HETATM 4579 C C2 . NAG EA 2 . ? 67.367 62.794 -7.774 1.00 114.68 ? 2000 NAG C C2 1 HETATM 4580 C C3 . NAG EA 2 . ? 68.177 62.451 -6.522 1.00 116.28 ? 2000 NAG C C3 1 HETATM 4581 C C4 . NAG EA 2 . ? 67.858 63.419 -5.385 1.00 116.30 ? 2000 NAG C C4 1 HETATM 4582 C C5 . NAG EA 2 . ? 66.353 63.457 -5.107 1.00 114.73 ? 2000 NAG C C5 1 HETATM 4583 C C6 . NAG EA 2 . ? 65.946 64.536 -4.128 1.00 114.68 ? 2000 NAG C C6 1 HETATM 4584 C C7 . NAG EA 2 . ? 67.664 62.119 -10.136 1.00 114.92 ? 2000 NAG C C7 1 HETATM 4585 C C8 . NAG EA 2 . ? 67.891 60.957 -11.054 1.00 114.21 ? 2000 NAG C C8 1 HETATM 4586 N N2 . NAG EA 2 . ? 67.629 61.824 -8.826 1.00 114.74 ? 2000 NAG C N2 1 HETATM 4587 O O3 . NAG EA 2 . ? 69.571 62.483 -6.812 1.00 116.90 ? 2000 NAG C O3 1 HETATM 4588 O O4 . NAG EA 2 . ? 68.554 63.003 -4.213 1.00 117.20 ? 2000 NAG C O4 1 HETATM 4589 O O5 . NAG EA 2 . ? 65.630 63.709 -6.324 1.00 113.09 ? 2000 NAG C O5 1 HETATM 4590 O O6 . NAG EA 2 . ? 66.209 65.843 -4.631 1.00 114.64 ? 2000 NAG C O6 1 HETATM 4591 O O7 . NAG EA 2 . ? 67.506 63.262 -10.560 1.00 115.48 ? 2000 NAG C O7 1 HETATM 4592 O O . HOH FA 6 . ? 64.336 35.512 25.405 1.00 67.91 ? 2001 HOH A O 1 HETATM 4593 O O . HOH FA 6 . ? 60.506 35.503 20.958 1.00 30.57 ? 2002 HOH A O 1 HETATM 4594 O O . HOH FA 6 . ? 62.237 33.900 23.538 1.00 44.08 ? 2003 HOH A O 1 HETATM 4595 O O . HOH FA 6 . ? 56.572 42.444 23.702 1.00 69.98 ? 2004 HOH A O 1 HETATM 4596 O O . HOH FA 6 . ? 59.493 37.634 19.297 1.00 49.37 ? 2005 HOH A O 1 HETATM 4597 O O . HOH FA 6 . ? 58.276 39.360 15.315 1.00 53.55 ? 2006 HOH A O 1 HETATM 4598 O O . HOH FA 6 . ? 55.586 42.518 20.459 1.00 59.03 ? 2007 HOH A O 1 HETATM 4599 O O . HOH FA 6 . ? 52.036 41.706 16.479 1.00 68.08 ? 2008 HOH A O 1 HETATM 4600 O O . HOH FA 6 . ? 49.403 44.069 20.451 1.00 52.16 ? 2009 HOH A O 1 HETATM 4601 O O . HOH FA 6 . ? 48.755 42.454 17.002 1.00 55.84 ? 2010 HOH A O 1 HETATM 4602 O O . HOH FA 6 . ? 59.520 44.956 24.126 1.00 59.73 ? 2011 HOH A O 1 HETATM 4603 O O . HOH FA 6 . ? 42.324 40.897 14.891 1.00 51.11 ? 2012 HOH A O 1 HETATM 4604 O O . HOH FA 6 . ? 36.517 44.813 13.394 1.00 61.14 ? 2013 HOH A O 1 HETATM 4605 O O . HOH FA 6 . ? 33.435 43.964 15.189 1.00 66.03 ? 2014 HOH A O 1 HETATM 4606 O O . HOH FA 6 . ? 34.729 39.759 16.658 1.00 48.59 ? 2015 HOH A O 1 HETATM 4607 O O . HOH FA 6 . ? 35.115 31.386 17.879 1.00 52.49 ? 2016 HOH A O 1 HETATM 4608 O O . HOH FA 6 . ? 58.978 36.134 11.355 1.00 58.60 ? 2017 HOH A O 1 HETATM 4609 O O . HOH FA 6 . ? 34.239 36.448 11.188 1.00 63.92 ? 2018 HOH A O 1 HETATM 4610 O O . HOH FA 6 . ? 39.706 36.109 9.660 1.00 52.74 ? 2019 HOH A O 1 HETATM 4611 O O . HOH FA 6 . ? 47.087 36.874 13.167 1.00 54.62 ? 2020 HOH A O 1 HETATM 4612 O O . HOH FA 6 . ? 52.233 35.332 10.313 1.00 56.08 ? 2021 HOH A O 1 HETATM 4613 O O . HOH FA 6 . ? 52.690 35.941 12.994 1.00 46.08 ? 2022 HOH A O 1 HETATM 4614 O O . HOH FA 6 . ? 61.444 34.513 13.312 1.00 32.10 ? 2023 HOH A O 1 HETATM 4615 O O . HOH FA 6 . ? 47.521 33.729 29.364 1.00 52.21 ? 2024 HOH A O 1 HETATM 4616 O O . HOH FA 6 . ? 62.063 35.376 9.621 1.00 52.68 ? 2025 HOH A O 1 HETATM 4617 O O . HOH FA 6 . ? 62.160 34.567 3.355 1.00 58.52 ? 2026 HOH A O 1 HETATM 4618 O O . HOH FA 6 . ? 64.920 35.294 6.149 1.00 24.63 ? 2027 HOH A O 1 HETATM 4619 O O . HOH FA 6 . ? 60.925 31.755 3.156 1.00 62.67 ? 2028 HOH A O 1 HETATM 4620 O O . HOH FA 6 . ? 64.038 26.617 6.499 1.00 46.91 ? 2029 HOH A O 1 HETATM 4621 O O . HOH FA 6 . ? 48.133 19.587 13.469 1.00 47.90 ? 2030 HOH A O 1 HETATM 4622 O O . HOH FA 6 . ? 66.734 26.468 0.814 1.00 64.66 ? 2031 HOH A O 1 HETATM 4623 O O . HOH FA 6 . ? 62.987 24.994 7.970 1.00 37.94 ? 2032 HOH A O 1 HETATM 4624 O O . HOH FA 6 . ? 70.011 26.057 10.367 1.00 51.74 ? 2033 HOH A O 1 HETATM 4625 O O . HOH FA 6 . ? 64.037 22.441 7.061 1.00 55.49 ? 2034 HOH A O 1 HETATM 4626 O O . HOH FA 6 . ? 65.083 18.455 7.633 1.00 61.67 ? 2035 HOH A O 1 HETATM 4627 O O . HOH FA 6 . ? 60.864 20.892 18.704 1.00 34.66 ? 2036 HOH A O 1 HETATM 4628 O O . HOH FA 6 . ? 60.620 20.993 21.315 1.00 42.96 ? 2037 HOH A O 1 HETATM 4629 O O . HOH FA 6 . ? 54.103 28.145 25.370 1.00 28.52 ? 2038 HOH A O 1 HETATM 4630 O O . HOH FA 6 . ? 57.849 25.979 26.318 1.00 62.56 ? 2039 HOH A O 1 HETATM 4631 O O . HOH FA 6 . ? 48.371 25.323 29.835 1.00 40.32 ? 2040 HOH A O 1 HETATM 4632 O O . HOH FA 6 . ? 49.718 26.336 31.963 1.00 59.76 ? 2041 HOH A O 1 HETATM 4633 O O . HOH FA 6 . ? 42.677 30.167 28.020 1.00 50.08 ? 2042 HOH A O 1 HETATM 4634 O O . HOH FA 6 . ? 43.301 25.683 23.524 1.00 53.18 ? 2043 HOH A O 1 HETATM 4635 O O . HOH FA 6 . ? 45.418 31.988 29.326 1.00 44.44 ? 2044 HOH A O 1 HETATM 4636 O O . HOH FA 6 . ? 48.936 18.231 25.484 1.00 33.68 ? 2045 HOH A O 1 HETATM 4637 O O . HOH FA 6 . ? 70.444 16.870 14.193 1.00 63.22 ? 2046 HOH A O 1 HETATM 4638 O O . HOH FA 6 . ? 50.894 18.529 14.063 1.00 52.00 ? 2047 HOH A O 1 HETATM 4639 O O . HOH FA 6 . ? 56.219 14.887 15.467 1.00 54.84 ? 2048 HOH A O 1 HETATM 4640 O O . HOH FA 6 . ? 32.309 37.356 20.400 1.00 54.17 ? 2049 HOH A O 1 HETATM 4641 O O . HOH FA 6 . ? 64.615 13.239 12.956 1.00 73.20 ? 2050 HOH A O 1 HETATM 4642 O O . HOH FA 6 . ? 63.696 7.082 8.470 1.00 71.78 ? 2051 HOH A O 1 HETATM 4643 O O . HOH FA 6 . ? 58.672 7.614 10.119 1.00 49.78 ? 2052 HOH A O 1 HETATM 4644 O O . HOH FA 6 . ? 52.520 13.985 7.826 1.00 79.00 ? 2053 HOH A O 1 HETATM 4645 O O . HOH FA 6 . ? 18.046 49.518 33.017 1.00 65.32 ? 2054 HOH A O 1 HETATM 4646 O O . HOH FA 6 . ? 55.315 16.998 2.136 1.00 62.78 ? 2055 HOH A O 1 HETATM 4647 O O . HOH FA 6 . ? 56.705 12.771 14.223 1.00 49.65 ? 2056 HOH A O 1 HETATM 4648 O O . HOH FA 6 . ? 51.971 11.473 10.470 1.00 59.58 ? 2057 HOH A O 1 HETATM 4649 O O . HOH FA 6 . ? 49.564 12.603 9.593 1.00 70.92 ? 2058 HOH A O 1 HETATM 4650 O O . HOH FA 6 . ? 41.117 42.905 29.880 1.00 44.72 ? 2059 HOH A O 1 HETATM 4651 O O . HOH FA 6 . ? 37.275 51.242 31.889 1.00 51.29 ? 2060 HOH A O 1 HETATM 4652 O O . HOH FA 6 . ? 39.388 52.493 23.558 1.00 55.09 ? 2061 HOH A O 1 HETATM 4653 O O . HOH FA 6 . ? 32.625 55.195 34.000 1.00 73.88 ? 2062 HOH A O 1 HETATM 4654 O O . HOH FA 6 . ? 29.694 59.604 32.070 1.00 49.18 ? 2063 HOH A O 1 HETATM 4655 O O . HOH FA 6 . ? 31.368 58.163 34.187 1.00 58.87 ? 2064 HOH A O 1 HETATM 4656 O O . HOH FA 6 . ? 48.656 12.704 16.444 1.00 44.39 ? 2065 HOH A O 1 HETATM 4657 O O . HOH FA 6 . ? 46.008 19.894 15.611 1.00 43.52 ? 2066 HOH A O 1 HETATM 4658 O O . HOH FA 6 . ? 26.121 68.023 21.844 1.00 56.93 ? 2067 HOH A O 1 HETATM 4659 O O . HOH FA 6 . ? 42.776 21.314 16.458 1.00 56.20 ? 2068 HOH A O 1 HETATM 4660 O O . HOH FA 6 . ? 21.356 53.471 37.598 1.00 53.02 ? 2069 HOH A O 1 HETATM 4661 O O . HOH FA 6 . ? 23.874 46.955 36.364 1.00 66.60 ? 2070 HOH A O 1 HETATM 4662 O O . HOH FA 6 . ? 28.451 43.457 39.642 1.00 65.68 ? 2071 HOH A O 1 HETATM 4663 O O . HOH FA 6 . ? 39.968 19.099 16.136 1.00 59.77 ? 2072 HOH A O 1 HETATM 4664 O O . HOH FA 6 . ? 43.277 25.598 12.368 1.00 45.14 ? 2073 HOH A O 1 HETATM 4665 O O . HOH FA 6 . ? 40.875 23.862 12.332 1.00 49.85 ? 2074 HOH A O 1 HETATM 4666 O O . HOH FA 6 . ? 37.394 27.959 17.617 1.00 47.95 ? 2075 HOH A O 1 HETATM 4667 O O . HOH FA 6 . ? 47.650 20.185 10.907 1.00 29.26 ? 2076 HOH A O 1 HETATM 4668 O O . HOH FA 6 . ? 53.427 25.915 8.284 1.00 35.18 ? 2077 HOH A O 1 HETATM 4669 O O . HOH FA 6 . ? 49.912 22.220 2.719 1.00 51.46 ? 2078 HOH A O 1 HETATM 4670 O O . HOH FA 6 . ? 54.391 25.141 2.323 1.00 67.70 ? 2079 HOH A O 1 HETATM 4671 O O . HOH FA 6 . ? 35.570 60.572 25.760 1.00 69.31 ? 2080 HOH A O 1 HETATM 4672 O O . HOH FA 6 . ? 56.667 26.479 5.435 1.00 49.95 ? 2081 HOH A O 1 HETATM 4673 O O . HOH FA 6 . ? 42.813 49.142 24.619 1.00 59.11 ? 2082 HOH A O 1 HETATM 4674 O O . HOH FA 6 . ? 44.644 49.425 22.041 1.00 69.11 ? 2083 HOH A O 1 HETATM 4675 O O . HOH FA 6 . ? 28.646 50.153 14.383 1.00 60.80 ? 2084 HOH A O 1 HETATM 4676 O O . HOH FA 6 . ? 51.087 34.296 6.290 1.00 61.47 ? 2085 HOH A O 1 HETATM 4677 O O . HOH FA 6 . ? 34.773 31.695 23.358 1.00 52.66 ? 2086 HOH A O 1 HETATM 4678 O O . HOH FA 6 . ? 36.524 29.693 24.614 1.00 47.63 ? 2087 HOH A O 1 HETATM 4679 O O . HOH FA 6 . ? 40.599 33.398 28.083 1.00 65.16 ? 2088 HOH A O 1 HETATM 4680 O O . HOH FA 6 . ? 44.096 39.653 29.051 1.00 73.45 ? 2089 HOH A O 1 HETATM 4681 O O . HOH FA 6 . ? 58.159 29.862 26.411 1.00 44.42 ? 2090 HOH A O 1 HETATM 4682 O O . HOH FA 6 . ? 70.175 19.837 18.192 1.00 63.91 ? 2091 HOH A O 1 HETATM 4683 O O . HOH FA 6 . ? 70.129 26.959 12.792 1.00 66.70 ? 2092 HOH A O 1 HETATM 4684 O O . HOH FA 6 . ? 68.431 16.575 16.046 1.00 63.13 ? 2093 HOH A O 1 HETATM 4685 O O . HOH FA 6 . ? 73.335 17.419 15.594 1.00 57.76 ? 2094 HOH A O 1 HETATM 4686 O O . HOH FA 6 . ? 72.801 19.346 18.342 1.00 70.65 ? 2095 HOH A O 1 HETATM 4687 O O . HOH FA 6 . ? 76.701 26.562 10.876 1.00 61.11 ? 2096 HOH A O 1 HETATM 4688 O O . HOH FA 6 . ? 71.177 25.302 21.911 1.00 30.48 ? 2097 HOH A O 1 HETATM 4689 O O . HOH FA 6 . ? 63.775 25.914 22.073 1.00 35.62 ? 2098 HOH A O 1 HETATM 4690 O O . HOH FA 6 . ? 60.185 37.890 13.327 1.00 47.10 ? 2099 HOH A O 1 HETATM 4691 O O . HOH FA 6 . ? 56.170 37.633 14.067 1.00 51.43 ? 2100 HOH A O 1 HETATM 4692 O O . HOH FA 6 . ? 48.223 36.136 27.292 1.00 64.70 ? 2101 HOH A O 1 HETATM 4693 O O . HOH FA 6 . ? 51.289 36.901 30.119 1.00 58.24 ? 2102 HOH A O 1 HETATM 4694 O O . HOH FA 6 . ? 47.627 37.650 30.123 1.00 79.77 ? 2103 HOH A O 1 HETATM 4695 O O . HOH FA 6 . ? 30.868 40.117 20.654 1.00 57.76 ? 2104 HOH A O 1 HETATM 4696 O O . HOH FA 6 . ? 30.141 39.879 23.759 1.00 64.64 ? 2105 HOH A O 1 HETATM 4697 O O . HOH FA 6 . ? 27.280 45.712 19.275 1.00 31.25 ? 2106 HOH A O 1 HETATM 4698 O O . HOH FA 6 . ? 23.415 38.126 21.690 1.00 61.47 ? 2107 HOH A O 1 HETATM 4699 O O . HOH FA 6 . ? 18.367 49.129 22.038 1.00 60.17 ? 2108 HOH A O 1 HETATM 4700 O O . HOH FA 6 . ? 15.714 50.492 22.399 1.00 59.92 ? 2109 HOH A O 1 HETATM 4701 O O . HOH FA 6 . ? 25.786 51.261 17.898 1.00 40.38 ? 2110 HOH A O 1 HETATM 4702 O O . HOH FA 6 . ? 10.490 56.584 27.660 1.00 67.21 ? 2111 HOH A O 1 HETATM 4703 O O . HOH FA 6 . ? 13.899 59.664 28.364 1.00 40.31 ? 2112 HOH A O 1 HETATM 4704 O O . HOH FA 6 . ? 8.408 59.933 30.656 1.00 75.09 ? 2113 HOH A O 1 HETATM 4705 O O . HOH FA 6 . ? 11.998 64.284 38.569 1.00 84.74 ? 2114 HOH A O 1 HETATM 4706 O O . HOH FA 6 . ? 16.956 64.440 31.887 1.00 53.31 ? 2115 HOH A O 1 HETATM 4707 O O . HOH FA 6 . ? 15.817 54.102 33.337 1.00 54.84 ? 2116 HOH A O 1 HETATM 4708 O O . HOH FA 6 . ? 19.145 45.208 28.081 1.00 58.89 ? 2117 HOH A O 1 HETATM 4709 O O . HOH FA 6 . ? 20.877 49.261 32.828 1.00 50.64 ? 2118 HOH A O 1 HETATM 4710 O O . HOH FA 6 . ? 32.297 46.129 27.865 1.00 27.57 ? 2119 HOH A O 1 HETATM 4711 O O . HOH FA 6 . ? 31.392 37.942 25.055 1.00 61.23 ? 2120 HOH A O 1 HETATM 4712 O O . HOH FA 6 . ? 42.036 42.183 27.420 1.00 42.90 ? 2121 HOH A O 1 HETATM 4713 O O . HOH FA 6 . ? 38.143 49.816 26.060 1.00 38.88 ? 2122 HOH A O 1 HETATM 4714 O O . HOH FA 6 . ? 34.715 50.993 31.743 1.00 42.05 ? 2123 HOH A O 1 HETATM 4715 O O . HOH FA 6 . ? 33.644 56.524 25.320 1.00 46.91 ? 2124 HOH A O 1 HETATM 4716 O O . HOH FA 6 . ? 37.857 52.492 25.802 1.00 59.09 ? 2125 HOH A O 1 HETATM 4717 O O . HOH FA 6 . ? 36.749 53.872 32.372 1.00 44.92 ? 2126 HOH A O 1 HETATM 4718 O O . HOH FA 6 . ? 32.877 53.607 31.286 1.00 29.18 ? 2127 HOH A O 1 HETATM 4719 O O . HOH FA 6 . ? 30.133 57.082 32.074 1.00 38.19 ? 2128 HOH A O 1 HETATM 4720 O O . HOH FA 6 . ? 29.352 60.962 23.126 1.00 50.20 ? 2129 HOH A O 1 HETATM 4721 O O . HOH FA 6 . ? 32.002 61.112 24.023 1.00 55.44 ? 2130 HOH A O 1 HETATM 4722 O O . HOH FA 6 . ? 30.458 60.950 29.851 1.00 40.95 ? 2131 HOH A O 1 HETATM 4723 O O . HOH FA 6 . ? 23.641 65.055 21.413 1.00 56.49 ? 2132 HOH A O 1 HETATM 4724 O O . HOH FA 6 . ? 23.112 67.316 33.961 1.00 62.75 ? 2133 HOH A O 1 HETATM 4725 O O . HOH FA 6 . ? 29.047 62.898 31.446 1.00 53.84 ? 2134 HOH A O 1 HETATM 4726 O O . HOH FA 6 . ? 21.978 60.009 38.617 1.00 63.54 ? 2135 HOH A O 1 HETATM 4727 O O . HOH FA 6 . ? 28.890 57.369 35.277 1.00 49.90 ? 2136 HOH A O 1 HETATM 4728 O O . HOH FA 6 . ? 23.558 51.695 35.690 1.00 46.04 ? 2137 HOH A O 1 HETATM 4729 O O . HOH FA 6 . ? 31.848 51.759 36.434 1.00 45.87 ? 2138 HOH A O 1 HETATM 4730 O O . HOH FA 6 . ? 26.820 46.157 34.732 1.00 50.24 ? 2139 HOH A O 1 HETATM 4731 O O . HOH FA 6 . ? 21.426 47.867 38.941 1.00 69.01 ? 2140 HOH A O 1 HETATM 4732 O O . HOH FA 6 . ? 22.092 53.004 41.408 1.00 69.62 ? 2141 HOH A O 1 HETATM 4733 O O . HOH FA 6 . ? 28.729 46.256 39.673 1.00 39.79 ? 2142 HOH A O 1 HETATM 4734 O O . HOH FA 6 . ? 23.464 41.745 37.217 1.00 65.28 ? 2143 HOH A O 1 HETATM 4735 O O . HOH FA 6 . ? 35.337 30.892 32.521 1.00 68.46 ? 2144 HOH A O 1 HETATM 4736 O O . HOH FA 6 . ? 26.210 40.358 30.335 1.00 56.89 ? 2145 HOH A O 1 HETATM 4737 O O . HOH FA 6 . ? 21.493 57.877 37.123 1.00 51.33 ? 2146 HOH A O 1 HETATM 4738 O O . HOH FA 6 . ? 18.317 52.255 34.435 1.00 68.39 ? 2147 HOH A O 1 HETATM 4739 O O . HOH FA 6 . ? 20.148 62.978 38.031 1.00 67.65 ? 2148 HOH A O 1 HETATM 4740 O O . HOH FA 6 . ? 13.981 76.708 26.861 1.00 65.52 ? 2149 HOH A O 1 HETATM 4741 O O . HOH FA 6 . ? 25.703 59.440 17.755 1.00 59.68 ? 2150 HOH A O 1 HETATM 4742 O O . HOH FA 6 . ? 28.777 60.405 20.629 1.00 49.74 ? 2151 HOH A O 1 HETATM 4743 O O . HOH FA 6 . ? 32.330 49.700 20.972 1.00 36.80 ? 2152 HOH A O 1 HETATM 4744 O O . HOH FA 6 . ? 36.552 57.429 25.896 1.00 61.26 ? 2153 HOH A O 1 HETATM 4745 O O . HOH FA 6 . ? 39.659 48.753 24.353 1.00 51.80 ? 2154 HOH A O 1 HETATM 4746 O O . HOH FA 6 . ? 42.713 46.444 23.907 1.00 51.27 ? 2155 HOH A O 1 HETATM 4747 O O . HOH FA 6 . ? 42.023 51.465 22.958 1.00 76.81 ? 2156 HOH A O 1 HETATM 4748 O O . HOH FA 6 . ? 33.712 47.101 18.950 1.00 44.10 ? 2157 HOH A O 1 HETATM 4749 O O . HOH FA 6 . ? 36.271 52.803 15.627 1.00 58.14 ? 2158 HOH A O 1 HETATM 4750 O O . HOH FA 6 . ? 32.525 49.728 15.053 1.00 61.29 ? 2159 HOH A O 1 HETATM 4751 O O . HOH FA 6 . ? 34.133 57.479 17.593 1.00 51.08 ? 2160 HOH A O 1 HETATM 4752 O O . HOH FA 6 . ? 26.917 49.448 16.665 1.00 43.51 ? 2161 HOH A O 1 HETATM 4753 O O . HOH FA 6 . ? 29.603 45.560 16.167 1.00 63.45 ? 2162 HOH A O 1 HETATM 4754 O O . HOH FA 6 . ? 28.951 53.275 15.185 1.00 64.19 ? 2163 HOH A O 1 HETATM 4755 O O . HOH FA 6 . ? 25.848 52.703 15.684 1.00 32.61 ? 2164 HOH A O 1 HETATM 4756 O O . HOH FA 6 . ? 31.441 56.195 16.354 1.00 59.65 ? 2165 HOH A O 1 HETATM 4757 O O . HOH FA 6 . ? 22.198 62.661 16.280 1.00 42.46 ? 2166 HOH A O 1 HETATM 4758 O O . HOH FA 6 . ? 12.066 58.170 22.344 1.00 48.18 ? 2167 HOH A O 1 HETATM 4759 O O . HOH FA 6 . ? 7.244 62.335 26.198 1.00 77.44 ? 2168 HOH A O 1 HETATM 4760 O O . HOH FA 6 . ? 48.628 14.002 6.908 1.00 66.64 ? 2169 HOH A O 1 HETATM 4761 O O . HOH FA 6 . ? 55.970 39.117 4.202 1.00 81.46 ? 2170 HOH A O 1 HETATM 4762 O O . HOH FA 6 . ? 33.162 31.402 26.922 1.00 50.80 ? 2171 HOH A O 1 HETATM 4763 O O . HOH FA 6 . ? 25.381 34.708 30.232 1.00 61.86 ? 2172 HOH A O 1 HETATM 4764 O O . HOH FA 6 . ? 35.017 59.756 19.397 1.00 60.58 ? 2173 HOH A O 1 HETATM 4765 O O . HOH GA 6 . ? 24.767 60.595 15.028 1.00 36.44 ? 2001 HOH B O 1 HETATM 4766 O O . HOH GA 6 . ? 28.978 65.810 15.727 1.00 69.51 ? 2002 HOH B O 1 HETATM 4767 O O . HOH GA 6 . ? 32.012 64.909 13.436 1.00 77.13 ? 2003 HOH B O 1 HETATM 4768 O O . HOH GA 6 . ? 27.482 59.720 15.034 1.00 49.84 ? 2004 HOH B O 1 HETATM 4769 O O . HOH GA 6 . ? 33.420 62.092 12.800 1.00 56.15 ? 2005 HOH B O 1 HETATM 4770 O O . HOH GA 6 . ? 36.082 60.103 8.589 1.00 70.52 ? 2006 HOH B O 1 HETATM 4771 O O . HOH GA 6 . ? 36.030 59.841 5.940 1.00 41.99 ? 2007 HOH B O 1 HETATM 4772 O O . HOH GA 6 . ? 35.230 66.991 2.472 1.00 58.92 ? 2008 HOH B O 1 HETATM 4773 O O . HOH GA 6 . ? 31.688 63.825 16.726 1.00 73.56 ? 2009 HOH B O 1 HETATM 4774 O O . HOH GA 6 . ? 36.475 62.834 10.005 1.00 76.28 ? 2010 HOH B O 1 HETATM 4775 O O . HOH GA 6 . ? 36.689 69.605 1.594 1.00 72.78 ? 2011 HOH B O 1 HETATM 4776 O O . HOH GA 6 . ? 36.703 57.593 -0.834 1.00 54.44 ? 2012 HOH B O 1 HETATM 4777 O O . HOH GA 6 . ? 40.597 60.902 -0.904 1.00 51.65 ? 2013 HOH B O 1 HETATM 4778 O O . HOH GA 6 . ? 42.607 58.467 -5.028 1.00 65.38 ? 2014 HOH B O 1 HETATM 4779 O O . HOH GA 6 . ? 37.551 59.521 -8.560 1.00 55.66 ? 2015 HOH B O 1 HETATM 4780 O O . HOH GA 6 . ? 43.128 59.208 -1.661 1.00 65.87 ? 2016 HOH B O 1 HETATM 4781 O O . HOH GA 6 . ? 39.813 56.309 -2.380 1.00 58.56 ? 2017 HOH B O 1 HETATM 4782 O O . HOH GA 6 . ? 40.616 60.104 -11.175 1.00 52.44 ? 2018 HOH B O 1 HETATM 4783 O O . HOH GA 6 . ? 29.866 58.884 -10.277 1.00 59.07 ? 2019 HOH B O 1 HETATM 4784 O O . HOH GA 6 . ? 37.046 56.418 -11.244 1.00 63.33 ? 2020 HOH B O 1 HETATM 4785 O O . HOH GA 6 . ? 34.371 55.671 2.216 1.00 73.06 ? 2021 HOH B O 1 HETATM 4786 O O . HOH GA 6 . ? 24.983 40.809 14.723 1.00 73.39 ? 2022 HOH B O 1 HETATM 4787 O O . HOH GA 6 . ? 35.010 51.197 -4.656 1.00 61.47 ? 2023 HOH B O 1 HETATM 4788 O O . HOH GA 6 . ? 30.120 42.793 -0.975 1.00 72.24 ? 2024 HOH B O 1 HETATM 4789 O O . HOH GA 6 . ? 32.576 53.828 2.987 1.00 52.88 ? 2025 HOH B O 1 HETATM 4790 O O . HOH GA 6 . ? 29.735 53.605 8.269 1.00 50.97 ? 2026 HOH B O 1 HETATM 4791 O O . HOH GA 6 . ? 32.434 53.312 5.857 1.00 67.59 ? 2027 HOH B O 1 HETATM 4792 O O . HOH GA 6 . ? 14.872 68.699 1.800 1.00 68.03 ? 2028 HOH B O 1 HETATM 4793 O O . HOH GA 6 . ? 25.337 70.075 -2.721 1.00 43.43 ? 2029 HOH B O 1 HETATM 4794 O O . HOH GA 6 . ? 26.654 42.815 15.266 1.00 73.25 ? 2030 HOH B O 1 HETATM 4795 O O . HOH GA 6 . ? 27.847 43.267 18.130 1.00 53.38 ? 2031 HOH B O 1 HETATM 4796 O O . HOH GA 6 . ? 30.189 43.992 13.448 1.00 76.38 ? 2032 HOH B O 1 HETATM 4797 O O . HOH GA 6 . ? 16.722 63.383 -7.152 1.00 59.33 ? 2033 HOH B O 1 HETATM 4798 O O . HOH GA 6 . ? 19.401 44.012 16.435 1.00 49.50 ? 2034 HOH B O 1 HETATM 4799 O O . HOH GA 6 . ? 8.188 58.504 0.998 1.00 73.22 ? 2035 HOH B O 1 HETATM 4800 O O . HOH GA 6 . ? 16.377 42.325 18.964 1.00 56.82 ? 2036 HOH B O 1 HETATM 4801 O O . HOH GA 6 . ? 16.122 47.680 21.921 1.00 51.80 ? 2037 HOH B O 1 HETATM 4802 O O . HOH GA 6 . ? 12.012 54.461 11.395 1.00 37.76 ? 2038 HOH B O 1 HETATM 4803 O O . HOH GA 6 . ? 9.178 55.190 7.661 1.00 57.29 ? 2039 HOH B O 1 HETATM 4804 O O . HOH GA 6 . ? 18.940 63.355 6.784 1.00 36.81 ? 2040 HOH B O 1 HETATM 4805 O O . HOH GA 6 . ? 18.523 64.308 -1.428 1.00 58.41 ? 2041 HOH B O 1 HETATM 4806 O O . HOH GA 6 . ? 21.635 68.764 3.413 1.00 51.73 ? 2042 HOH B O 1 HETATM 4807 O O . HOH GA 6 . ? 16.775 67.297 0.530 1.00 41.11 ? 2043 HOH B O 1 HETATM 4808 O O . HOH GA 6 . ? 26.502 68.551 -4.618 1.00 46.20 ? 2044 HOH B O 1 HETATM 4809 O O . HOH GA 6 . ? 23.965 68.626 -0.585 1.00 34.59 ? 2045 HOH B O 1 HETATM 4810 O O . HOH GA 6 . ? 34.548 71.884 -0.949 1.00 50.90 ? 2046 HOH B O 1 HETATM 4811 O O . HOH GA 6 . ? 33.048 73.276 2.124 1.00 58.32 ? 2047 HOH B O 1 HETATM 4812 O O . HOH GA 6 . ? 19.430 73.161 2.491 1.00 57.76 ? 2048 HOH B O 1 HETATM 4813 O O . HOH GA 6 . ? 25.358 72.432 -4.652 1.00 72.37 ? 2049 HOH B O 1 HETATM 4814 O O . HOH GA 6 . ? 15.770 70.093 -1.135 1.00 56.71 ? 2050 HOH B O 1 HETATM 4815 O O . HOH GA 6 . ? 15.996 62.536 -4.363 1.00 34.14 ? 2051 HOH B O 1 HETATM 4816 O O . HOH GA 6 . ? 12.614 67.903 -0.444 1.00 55.93 ? 2052 HOH B O 1 HETATM 4817 O O . HOH GA 6 . ? 11.345 61.721 -2.689 1.00 60.06 ? 2053 HOH B O 1 HETATM 4818 O O . HOH GA 6 . ? 11.661 62.138 2.042 1.00 44.64 ? 2054 HOH B O 1 HETATM 4819 O O . HOH GA 6 . ? 10.710 64.342 -0.567 1.00 52.64 ? 2055 HOH B O 1 HETATM 4820 O O . HOH GA 6 . ? 9.810 55.408 0.869 1.00 58.40 ? 2056 HOH B O 1 HETATM 4821 O O . HOH GA 6 . ? 8.923 50.199 5.528 1.00 51.67 ? 2057 HOH B O 1 HETATM 4822 O O . HOH GA 6 . ? 13.250 41.453 2.372 1.00 71.56 ? 2058 HOH B O 1 HETATM 4823 O O . HOH GA 6 . ? 6.490 50.537 7.087 1.00 68.07 ? 2059 HOH B O 1 HETATM 4824 O O . HOH GA 6 . ? 9.034 38.944 10.629 1.00 75.75 ? 2060 HOH B O 1 HETATM 4825 O O . HOH GA 6 . ? 5.067 41.609 13.380 1.00 84.16 ? 2061 HOH B O 1 HETATM 4826 O O . HOH GA 6 . ? 43.248 82.026 -17.212 1.00 87.45 ? 2062 HOH B O 1 HETATM 4827 O O . HOH GA 6 . ? 7.149 48.608 4.564 1.00 63.20 ? 2063 HOH B O 1 HETATM 4828 O O . HOH GA 6 . ? 9.719 48.572 -1.905 1.00 52.53 ? 2064 HOH B O 1 HETATM 4829 O O . HOH GA 6 . ? 13.992 49.891 0.624 1.00 49.84 ? 2065 HOH B O 1 HETATM 4830 O O . HOH GA 6 . ? 36.049 73.773 0.306 1.00 62.60 ? 2066 HOH B O 1 HETATM 4831 O O . HOH GA 6 . ? 38.966 74.472 -0.365 1.00 64.43 ? 2067 HOH B O 1 HETATM 4832 O O . HOH GA 6 . ? 40.501 72.255 1.438 1.00 67.45 ? 2068 HOH B O 1 HETATM 4833 O O . HOH GA 6 . ? 9.228 55.452 3.509 1.00 55.40 ? 2069 HOH B O 1 HETATM 4834 O O . HOH GA 6 . ? 4.098 51.200 5.684 1.00 61.84 ? 2070 HOH B O 1 HETATM 4835 O O . HOH GA 6 . ? 46.368 68.794 -0.479 1.00 64.15 ? 2071 HOH B O 1 HETATM 4836 O O . HOH GA 6 . ? 57.009 70.831 -4.059 1.00 62.61 ? 2072 HOH B O 1 HETATM 4837 O O . HOH GA 6 . ? 8.178 54.905 -1.724 1.00 58.58 ? 2073 HOH B O 1 HETATM 4838 O O . HOH GA 6 . ? 16.493 52.037 -3.361 1.00 44.12 ? 2074 HOH B O 1 HETATM 4839 O O . HOH GA 6 . ? 56.608 78.068 -3.727 1.00 72.64 ? 2075 HOH B O 1 HETATM 4840 O O . HOH GA 6 . ? 13.532 59.043 -7.113 1.00 60.46 ? 2076 HOH B O 1 HETATM 4841 O O . HOH GA 6 . ? 9.853 61.050 -0.252 1.00 61.71 ? 2077 HOH B O 1 HETATM 4842 O O . HOH GA 6 . ? 13.618 61.053 -5.310 1.00 51.37 ? 2078 HOH B O 1 HETATM 4843 O O . HOH GA 6 . ? 18.437 54.131 -6.030 1.00 54.02 ? 2079 HOH B O 1 HETATM 4844 O O . HOH GA 6 . ? 46.655 84.795 -16.894 1.00 56.15 ? 2080 HOH B O 1 HETATM 4845 O O . HOH GA 6 . ? 43.772 82.856 -20.481 1.00 88.68 ? 2081 HOH B O 1 HETATM 4846 O O . HOH GA 6 . ? 20.069 53.850 -9.286 1.00 61.36 ? 2082 HOH B O 1 HETATM 4847 O O . HOH GA 6 . ? 18.670 57.559 -12.715 1.00 53.04 ? 2083 HOH B O 1 HETATM 4848 O O . HOH GA 6 . ? 19.273 60.817 -10.081 1.00 63.65 ? 2084 HOH B O 1 HETATM 4849 O O . HOH GA 6 . ? 21.610 63.801 -1.307 1.00 50.53 ? 2085 HOH B O 1 HETATM 4850 O O . HOH GA 6 . ? 22.636 50.735 -6.492 1.00 57.80 ? 2086 HOH B O 1 HETATM 4851 O O . HOH GA 6 . ? 23.724 50.910 -3.909 1.00 45.71 ? 2087 HOH B O 1 HETATM 4852 O O . HOH GA 6 . ? 25.760 57.004 -8.881 1.00 51.50 ? 2088 HOH B O 1 HETATM 4853 O O . HOH GA 6 . ? 49.328 85.922 -17.322 1.00 58.49 ? 2089 HOH B O 1 HETATM 4854 O O . HOH GA 6 . ? 45.892 84.430 -19.887 1.00 87.84 ? 2090 HOH B O 1 HETATM 4855 O O . HOH GA 6 . ? 48.764 88.984 -16.845 1.00 67.77 ? 2091 HOH B O 1 HETATM 4856 O O . HOH GA 6 . ? 21.580 52.450 -13.137 1.00 79.41 ? 2092 HOH B O 1 HETATM 4857 O O . HOH GA 6 . ? 21.207 46.508 5.715 1.00 48.63 ? 2093 HOH B O 1 HETATM 4858 O O . HOH GA 6 . ? 21.628 43.379 8.794 1.00 57.09 ? 2094 HOH B O 1 HETATM 4859 O O . HOH GA 6 . ? 41.701 69.549 1.244 1.00 51.04 ? 2095 HOH B O 1 HETATM 4860 O O . HOH GA 6 . ? 39.468 64.817 2.992 1.00 62.46 ? 2096 HOH B O 1 HETATM 4861 O O . HOH GA 6 . ? 49.436 60.926 -11.752 1.00 52.80 ? 2097 HOH B O 1 HETATM 4862 O O . HOH GA 6 . ? 25.300 44.990 6.914 1.00 50.24 ? 2098 HOH B O 1 HETATM 4863 O O . HOH GA 6 . ? 30.231 46.334 5.835 1.00 57.64 ? 2099 HOH B O 1 HETATM 4864 O O . HOH GA 6 . ? 29.914 50.666 7.539 1.00 57.43 ? 2100 HOH B O 1 HETATM 4865 O O . HOH GA 6 . ? 28.099 64.114 -10.533 1.00 49.43 ? 2101 HOH B O 1 HETATM 4866 O O . HOH GA 6 . ? 25.573 63.935 -9.763 1.00 52.11 ? 2102 HOH B O 1 HETATM 4867 O O . HOH GA 6 . ? 31.604 70.938 0.755 1.00 67.36 ? 2103 HOH B O 1 HETATM 4868 O O . HOH GA 6 . ? 27.460 67.153 3.388 1.00 58.09 ? 2104 HOH B O 1 HETATM 4869 O O . HOH GA 6 . ? 19.045 64.675 10.787 1.00 55.07 ? 2105 HOH B O 1 HETATM 4870 O O . HOH GA 6 . ? 10.112 59.887 9.332 1.00 59.08 ? 2106 HOH B O 1 HETATM 4871 O O . HOH GA 6 . ? 10.996 56.564 12.230 1.00 44.45 ? 2107 HOH B O 1 HETATM 4872 O O . HOH GA 6 . ? 8.627 53.535 20.229 1.00 56.80 ? 2108 HOH B O 1 HETATM 4873 O O . HOH GA 6 . ? 8.853 48.991 26.303 1.00 70.38 ? 2109 HOH B O 1 HETATM 4874 O O . HOH GA 6 . ? 11.568 58.091 14.833 1.00 64.94 ? 2110 HOH B O 1 HETATM 4875 O O . HOH GA 6 . ? 14.647 58.796 15.574 1.00 49.75 ? 2111 HOH B O 1 HETATM 4876 O O . HOH GA 6 . ? 30.363 55.107 11.762 1.00 57.48 ? 2112 HOH B O 1 HETATM 4877 O O . HOH GA 6 . ? 34.623 68.972 -0.040 1.00 73.25 ? 2113 HOH B O 1 HETATM 4878 O O . HOH GA 6 . ? 37.293 64.290 -11.935 1.00 63.25 ? 2114 HOH B O 1 HETATM 4879 O O . HOH GA 6 . ? 36.618 66.821 -12.447 1.00 62.11 ? 2115 HOH B O 1 HETATM 4880 O O . HOH GA 6 . ? 44.267 64.873 -14.331 1.00 33.98 ? 2116 HOH B O 1 HETATM 4881 O O . HOH GA 6 . ? 36.158 67.855 -15.596 1.00 52.99 ? 2117 HOH B O 1 HETATM 4882 O O . HOH GA 6 . ? 50.756 70.406 -24.046 1.00 61.13 ? 2118 HOH B O 1 HETATM 4883 O O . HOH GA 6 . ? 49.870 64.931 -14.081 1.00 38.42 ? 2119 HOH B O 1 HETATM 4884 O O . HOH GA 6 . ? 51.728 76.990 -26.307 1.00 58.31 ? 2120 HOH B O 1 HETATM 4885 O O . HOH GA 6 . ? 56.309 77.248 -26.808 1.00 62.22 ? 2121 HOH B O 1 HETATM 4886 O O . HOH GA 6 . ? 57.791 78.585 -23.086 1.00 40.64 ? 2122 HOH B O 1 HETATM 4887 O O . HOH GA 6 . ? 58.671 89.632 -22.770 1.00 73.50 ? 2123 HOH B O 1 HETATM 4888 O O . HOH GA 6 . ? 65.845 78.389 -22.298 1.00 66.98 ? 2124 HOH B O 1 HETATM 4889 O O . HOH GA 6 . ? 50.353 81.616 -22.388 1.00 62.46 ? 2125 HOH B O 1 HETATM 4890 O O . HOH GA 6 . ? 44.664 79.271 -18.949 1.00 46.92 ? 2126 HOH B O 1 HETATM 4891 O O . HOH GA 6 . ? 40.660 72.696 -8.969 1.00 29.94 ? 2127 HOH B O 1 HETATM 4892 O O . HOH GA 6 . ? 34.222 67.563 -12.227 1.00 69.60 ? 2128 HOH B O 1 HETATM 4893 O O . HOH GA 6 . ? 37.708 74.651 -2.648 1.00 51.02 ? 2129 HOH B O 1 HETATM 4894 O O . HOH GA 6 . ? 43.284 71.102 -2.418 1.00 30.30 ? 2130 HOH B O 1 HETATM 4895 O O . HOH GA 6 . ? 41.574 74.104 -1.577 1.00 53.79 ? 2131 HOH B O 1 HETATM 4896 O O . HOH GA 6 . ? 43.686 77.245 -5.205 1.00 57.92 ? 2132 HOH B O 1 HETATM 4897 O O . HOH GA 6 . ? 50.702 72.796 -5.045 1.00 38.64 ? 2133 HOH B O 1 HETATM 4898 O O . HOH GA 6 . ? 45.751 71.744 -1.719 1.00 55.66 ? 2134 HOH B O 1 HETATM 4899 O O . HOH GA 6 . ? 45.739 78.411 -2.264 1.00 48.16 ? 2135 HOH B O 1 HETATM 4900 O O . HOH GA 6 . ? 47.833 78.027 -3.956 1.00 61.80 ? 2136 HOH B O 1 HETATM 4901 O O . HOH GA 6 . ? 46.433 77.621 -6.319 1.00 28.57 ? 2137 HOH B O 1 HETATM 4902 O O . HOH GA 6 . ? 50.267 79.848 -7.870 1.00 51.02 ? 2138 HOH B O 1 HETATM 4903 O O . HOH GA 6 . ? 56.557 72.409 -8.119 1.00 39.22 ? 2139 HOH B O 1 HETATM 4904 O O . HOH GA 6 . ? 55.820 73.226 -5.920 1.00 53.82 ? 2140 HOH B O 1 HETATM 4905 O O . HOH GA 6 . ? 54.410 78.634 -6.609 1.00 41.88 ? 2141 HOH B O 1 HETATM 4906 O O . HOH GA 6 . ? 56.833 75.646 -4.834 1.00 54.67 ? 2142 HOH B O 1 HETATM 4907 O O . HOH GA 6 . ? 61.996 72.070 -12.157 1.00 50.22 ? 2143 HOH B O 1 HETATM 4908 O O . HOH GA 6 . ? 63.256 79.144 -6.860 1.00 44.37 ? 2144 HOH B O 1 HETATM 4909 O O . HOH GA 6 . ? 60.574 77.117 -6.025 1.00 72.06 ? 2145 HOH B O 1 HETATM 4910 O O . HOH GA 6 . ? 63.806 81.685 -11.059 1.00 64.29 ? 2146 HOH B O 1 HETATM 4911 O O . HOH GA 6 . ? 62.250 84.179 -11.566 1.00 55.37 ? 2147 HOH B O 1 HETATM 4912 O O . HOH GA 6 . ? 56.325 80.596 -6.625 1.00 55.27 ? 2148 HOH B O 1 HETATM 4913 O O . HOH GA 6 . ? 58.679 79.786 -3.232 1.00 44.51 ? 2149 HOH B O 1 HETATM 4914 O O . HOH GA 6 . ? 61.965 84.623 -5.825 1.00 51.14 ? 2150 HOH B O 1 HETATM 4915 O O . HOH GA 6 . ? 55.980 80.518 -8.899 1.00 55.93 ? 2151 HOH B O 1 HETATM 4916 O O . HOH GA 6 . ? 57.161 88.155 -15.819 1.00 67.82 ? 2152 HOH B O 1 HETATM 4917 O O . HOH GA 6 . ? 60.879 85.416 -13.329 1.00 76.72 ? 2153 HOH B O 1 HETATM 4918 O O . HOH GA 6 . ? 45.752 82.217 -15.895 1.00 52.91 ? 2154 HOH B O 1 HETATM 4919 O O . HOH GA 6 . ? 39.856 79.645 -13.913 1.00 53.98 ? 2155 HOH B O 1 HETATM 4920 O O . HOH GA 6 . ? 39.852 87.746 -14.374 1.00 54.02 ? 2156 HOH B O 1 HETATM 4921 O O . HOH GA 6 . ? 42.164 84.686 -18.432 1.00 62.84 ? 2157 HOH B O 1 HETATM 4922 O O . HOH GA 6 . ? 38.446 78.815 -15.867 1.00 58.14 ? 2158 HOH B O 1 HETATM 4923 O O . HOH GA 6 . ? 31.998 77.343 -17.139 1.00 63.48 ? 2159 HOH B O 1 HETATM 4924 O O . HOH GA 6 . ? 28.477 73.237 -12.291 1.00 48.74 ? 2160 HOH B O 1 HETATM 4925 O O . HOH GA 6 . ? 25.073 72.318 -10.812 1.00 62.97 ? 2161 HOH B O 1 HETATM 4926 O O . HOH GA 6 . ? 24.202 71.198 -6.987 1.00 76.12 ? 2162 HOH B O 1 HETATM 4927 O O . HOH GA 6 . ? 51.683 85.628 -16.245 1.00 47.09 ? 2163 HOH B O 1 HETATM 4928 O O . HOH GA 6 . ? 47.383 81.666 -20.476 1.00 56.81 ? 2164 HOH B O 1 HETATM 4929 O O . HOH GA 6 . ? 62.207 88.476 -18.795 1.00 61.98 ? 2165 HOH B O 1 HETATM 4930 O O . HOH GA 6 . ? 63.891 86.499 -10.390 1.00 55.02 ? 2166 HOH B O 1 HETATM 4931 O O . HOH GA 6 . ? 66.418 74.259 -15.907 1.00 57.27 ? 2167 HOH B O 1 HETATM 4932 O O . HOH GA 6 . ? 67.910 71.834 -17.379 1.00 70.82 ? 2168 HOH B O 1 HETATM 4933 O O . HOH GA 6 . ? 57.781 66.878 -12.638 1.00 44.20 ? 2169 HOH B O 1 HETATM 4934 O O . HOH GA 6 . ? 56.939 69.829 -8.538 1.00 38.39 ? 2170 HOH B O 1 HETATM 4935 O O . HOH GA 6 . ? 46.029 66.773 -8.162 1.00 27.87 ? 2171 HOH B O 1 HETATM 4936 O O . HOH GA 6 . ? 47.388 64.263 -1.140 1.00 63.10 ? 2172 HOH B O 1 HETATM 4937 O O . HOH GA 6 . ? 42.255 69.162 -1.416 1.00 44.16 ? 2173 HOH B O 1 HETATM 4938 O O . HOH GA 6 . ? 39.559 67.456 1.249 1.00 56.16 ? 2174 HOH B O 1 HETATM 4939 O O . HOH GA 6 . ? 43.849 63.998 -7.652 1.00 39.42 ? 2175 HOH B O 1 HETATM 4940 O O . HOH GA 6 . ? 49.363 62.098 -3.410 1.00 52.78 ? 2176 HOH B O 1 HETATM 4941 O O . HOH GA 6 . ? 53.657 65.366 -3.946 1.00 49.85 ? 2177 HOH B O 1 HETATM 4942 O O . HOH GA 6 . ? 48.330 62.996 -13.826 1.00 52.19 ? 2178 HOH B O 1 HETATM 4943 O O . HOH GA 6 . ? 52.181 62.763 -10.851 1.00 46.82 ? 2179 HOH B O 1 HETATM 4944 O O . HOH GA 6 . ? 52.249 63.360 -13.891 1.00 34.92 ? 2180 HOH B O 1 HETATM 4945 O O . HOH GA 6 . ? 53.313 64.555 -7.374 1.00 52.69 ? 2181 HOH B O 1 HETATM 4946 O O . HOH GA 6 . ? 62.004 66.809 -14.304 1.00 43.77 ? 2182 HOH B O 1 HETATM 4947 O O . HOH GA 6 . ? 58.573 72.809 -25.043 1.00 37.55 ? 2183 HOH B O 1 HETATM 4948 O O . HOH GA 6 . ? 62.257 67.980 -21.679 1.00 63.67 ? 2184 HOH B O 1 HETATM 4949 O O . HOH GA 6 . ? 62.547 81.639 -26.508 1.00 64.29 ? 2185 HOH B O 1 HETATM 4950 O O . HOH GA 6 . ? 64.729 79.578 -26.120 1.00 70.84 ? 2186 HOH B O 1 HETATM 4951 O O . HOH GA 6 . ? 62.067 78.410 -28.700 1.00 64.16 ? 2187 HOH B O 1 HETATM 4952 O O . HOH GA 6 . ? 11.108 42.764 -2.753 1.00 58.84 ? 2188 HOH B O 1 HETATM 4953 O O . HOH GA 6 . ? 21.002 54.803 -11.675 1.00 70.01 ? 2189 HOH B O 1 HETATM 4954 O O . HOH GA 6 . ? 25.181 60.878 -11.246 1.00 64.49 ? 2190 HOH B O 1 HETATM 4955 O O . HOH GA 6 . ? 30.416 48.785 12.815 1.00 60.21 ? 2191 HOH B O 1 HETATM 4956 O O . HOH GA 6 . ? 18.658 47.356 -6.137 1.00 68.59 ? 2192 HOH B O 1 HETATM 4957 O O . HOH GA 6 . ? 22.984 40.293 6.660 1.00 71.27 ? 2193 HOH B O 1 HETATM 4958 O O . HOH GA 6 . ? 27.508 66.710 -12.123 1.00 44.88 ? 2194 HOH B O 1 HETATM 4959 O O . HOH GA 6 . ? 35.992 71.952 -16.364 1.00 48.98 ? 2195 HOH B O 1 HETATM 4960 O O . HOH GA 6 . ? 52.772 62.791 -3.482 1.00 70.38 ? 2196 HOH B O 1 HETATM 4961 O O . HOH GA 6 . ? 53.841 73.598 -2.000 1.00 51.44 ? 2197 HOH B O 1 HETATM 4962 O O . HOH HA 6 . ? 63.437 69.629 -13.341 1.00 52.62 ? 2001 HOH C O 1 HETATM 4963 O O . HOH HA 6 . ? 65.506 65.239 -11.229 1.00 79.37 ? 2002 HOH C O 1 HETATM 4964 O O . HOH HA 6 . ? 59.768 64.760 -12.728 1.00 35.85 ? 2003 HOH C O 1 HETATM 4965 O O . HOH HA 6 . ? 59.305 64.291 -4.631 1.00 62.66 ? 2004 HOH C O 1 HETATM 4966 O O . HOH HA 6 . ? 54.449 62.042 -8.613 1.00 63.19 ? 2005 HOH C O 1 HETATM 4967 O O . HOH HA 6 . ? 58.178 64.284 -10.609 1.00 51.87 ? 2006 HOH C O 1 HETATM 4968 O O . HOH HA 6 . ? 59.721 61.646 -4.351 1.00 46.84 ? 2007 HOH C O 1 HETATM 4969 O O . HOH HA 6 . ? 56.677 56.998 -4.166 1.00 71.91 ? 2008 HOH C O 1 HETATM 4970 O O . HOH HA 6 . ? 58.437 58.535 -2.513 1.00 69.00 ? 2009 HOH C O 1 HETATM 4971 O O . HOH HA 6 . ? 66.596 65.209 -14.091 1.00 60.96 ? 2010 HOH C O 1 HETATM 4972 O O . HOH HA 6 . ? 58.021 54.256 -3.222 1.00 35.89 ? 2011 HOH C O 1 HETATM 4973 O O . HOH HA 6 . ? 62.750 52.694 1.425 1.00 63.59 ? 2012 HOH C O 1 HETATM 4974 O O . HOH HA 6 . ? 65.294 53.509 -1.552 1.00 60.13 ? 2013 HOH C O 1 HETATM 4975 O O . HOH HA 6 . ? 60.493 59.053 -0.983 1.00 64.52 ? 2014 HOH C O 1 HETATM 4976 O O . HOH HA 6 . ? 67.251 52.085 0.112 1.00 66.76 ? 2015 HOH C O 1 HETATM 4977 O O . HOH HA 6 . ? 57.461 46.827 -3.128 1.00 30.33 ? 2016 HOH C O 1 HETATM 4978 O O . HOH HA 6 . ? 58.400 42.103 2.722 1.00 52.72 ? 2017 HOH C O 1 HETATM 4979 O O . HOH HA 6 . ? 59.227 47.070 1.237 1.00 45.47 ? 2018 HOH C O 1 HETATM 4980 O O . HOH HA 6 . ? 60.865 40.537 -2.158 1.00 45.81 ? 2019 HOH C O 1 HETATM 4981 O O . HOH HA 6 . ? 55.876 42.427 1.445 1.00 67.02 ? 2020 HOH C O 1 HETATM 4982 O O . HOH HA 6 . ? 62.907 38.915 -2.074 1.00 59.01 ? 2021 HOH C O 1 HETATM 4983 O O . HOH HA 6 . ? 52.250 49.906 -7.390 1.00 66.60 ? 2022 HOH C O 1 HETATM 4984 O O . HOH HA 6 . ? 49.997 42.541 -17.634 1.00 64.84 ? 2023 HOH C O 1 HETATM 4985 O O . HOH HA 6 . ? 55.791 39.428 -10.133 1.00 40.89 ? 2024 HOH C O 1 HETATM 4986 O O . HOH HA 6 . ? 63.380 39.388 -10.124 1.00 39.26 ? 2025 HOH C O 1 HETATM 4987 O O . HOH HA 6 . ? 60.560 37.259 -3.224 1.00 57.67 ? 2026 HOH C O 1 HETATM 4988 O O . HOH HA 6 . ? 55.328 50.134 -5.686 1.00 69.22 ? 2027 HOH C O 1 HETATM 4989 O O . HOH HA 6 . ? 53.395 56.182 -8.092 1.00 66.11 ? 2028 HOH C O 1 HETATM 4990 O O . HOH HA 6 . ? 53.227 40.479 -4.169 1.00 79.12 ? 2029 HOH C O 1 HETATM 4991 O O . HOH HA 6 . ? 67.284 49.784 25.987 1.00 58.63 ? 2030 HOH C O 1 HETATM 4992 O O . HOH HA 6 . ? 53.511 42.310 -7.329 1.00 39.17 ? 2031 HOH C O 1 HETATM 4993 O O . HOH HA 6 . ? 52.425 47.682 -8.804 1.00 54.05 ? 2032 HOH C O 1 HETATM 4994 O O . HOH HA 6 . ? 49.984 42.189 -14.707 1.00 66.99 ? 2033 HOH C O 1 HETATM 4995 O O . HOH HA 6 . ? 49.945 41.900 -11.773 1.00 66.53 ? 2034 HOH C O 1 HETATM 4996 O O . HOH HA 6 . ? 48.920 46.469 -14.874 1.00 60.81 ? 2035 HOH C O 1 HETATM 4997 O O . HOH HA 6 . ? 48.751 46.289 -9.985 1.00 66.06 ? 2036 HOH C O 1 HETATM 4998 O O . HOH HA 6 . ? 54.797 50.434 -8.439 1.00 42.46 ? 2037 HOH C O 1 HETATM 4999 O O . HOH HA 6 . ? 51.381 53.940 -11.196 1.00 50.52 ? 2038 HOH C O 1 HETATM 5000 O O . HOH HA 6 . ? 53.702 55.687 -10.734 1.00 41.96 ? 2039 HOH C O 1 HETATM 5001 O O . HOH HA 6 . ? 52.713 52.345 -8.729 1.00 64.18 ? 2040 HOH C O 1 HETATM 5002 O O . HOH HA 6 . ? 62.634 61.040 -29.137 1.00 62.48 ? 2041 HOH C O 1 HETATM 5003 O O . HOH HA 6 . ? 70.972 54.317 -10.250 1.00 62.14 ? 2042 HOH C O 1 HETATM 5004 O O . HOH HA 6 . ? 72.645 49.984 -9.781 1.00 50.25 ? 2043 HOH C O 1 HETATM 5005 O O . HOH HA 6 . ? 82.093 48.942 -15.385 1.00 67.77 ? 2044 HOH C O 1 HETATM 5006 O O . HOH HA 6 . ? 45.454 62.524 -22.634 1.00 50.58 ? 2045 HOH C O 1 HETATM 5007 O O . HOH HA 6 . ? 64.781 51.367 -30.758 1.00 53.72 ? 2046 HOH C O 1 HETATM 5008 O O . HOH HA 6 . ? 57.073 47.663 -25.411 1.00 46.38 ? 2047 HOH C O 1 HETATM 5009 O O . HOH HA 6 . ? 43.361 69.596 -23.608 1.00 64.10 ? 2048 HOH C O 1 HETATM 5010 O O . HOH HA 6 . ? 47.260 61.413 -24.324 1.00 50.18 ? 2049 HOH C O 1 HETATM 5011 O O . HOH HA 6 . ? 47.993 68.894 -24.591 1.00 50.70 ? 2050 HOH C O 1 HETATM 5012 O O . HOH HA 6 . ? 70.191 50.560 -28.387 1.00 49.69 ? 2051 HOH C O 1 HETATM 5013 O O . HOH HA 6 . ? 46.849 61.238 -30.637 1.00 61.58 ? 2052 HOH C O 1 HETATM 5014 O O . HOH HA 6 . ? 65.873 37.455 -24.488 1.00 71.99 ? 2053 HOH C O 1 HETATM 5015 O O . HOH HA 6 . ? 58.578 61.424 -26.926 1.00 37.90 ? 2054 HOH C O 1 HETATM 5016 O O . HOH HA 6 . ? 61.128 58.224 -29.381 1.00 46.67 ? 2055 HOH C O 1 HETATM 5017 O O . HOH HA 6 . ? 66.341 58.578 -17.751 1.00 36.29 ? 2056 HOH C O 1 HETATM 5018 O O . HOH HA 6 . ? 67.058 60.845 -19.942 1.00 60.37 ? 2057 HOH C O 1 HETATM 5019 O O . HOH HA 6 . ? 71.350 56.204 -13.057 1.00 50.20 ? 2058 HOH C O 1 HETATM 5020 O O . HOH HA 6 . ? 70.087 60.249 -16.044 1.00 58.09 ? 2059 HOH C O 1 HETATM 5021 O O . HOH HA 6 . ? 72.507 53.357 -18.778 1.00 26.45 ? 2060 HOH C O 1 HETATM 5022 O O . HOH HA 6 . ? 74.865 55.775 -17.529 1.00 69.05 ? 2061 HOH C O 1 HETATM 5023 O O . HOH HA 6 . ? 70.917 48.741 -13.078 1.00 29.47 ? 2062 HOH C O 1 HETATM 5024 O O . HOH HA 6 . ? 72.869 57.367 -14.847 1.00 74.64 ? 2063 HOH C O 1 HETATM 5025 O O . HOH HA 6 . ? 73.619 49.450 -13.490 1.00 40.94 ? 2064 HOH C O 1 HETATM 5026 O O . HOH HA 6 . ? 71.547 52.061 -11.623 1.00 40.30 ? 2065 HOH C O 1 HETATM 5027 O O . HOH HA 6 . ? 72.474 41.610 -10.877 1.00 45.10 ? 2066 HOH C O 1 HETATM 5028 O O . HOH HA 6 . ? 73.307 45.460 -12.283 1.00 63.89 ? 2067 HOH C O 1 HETATM 5029 O O . HOH HA 6 . ? 72.872 42.073 -13.995 0.50 104.02 ? 2068 HOH C O 1 HETATM 5030 O O . HOH HA 6 . ? 76.149 53.063 -18.368 1.00 56.27 ? 2069 HOH C O 1 HETATM 5031 O O . HOH HA 6 . ? 80.204 51.509 -15.898 1.00 67.10 ? 2070 HOH C O 1 HETATM 5032 O O . HOH HA 6 . ? 67.571 62.542 -14.626 1.00 69.82 ? 2071 HOH C O 1 HETATM 5033 O O . HOH HA 6 . ? 65.229 58.376 -27.854 1.00 66.84 ? 2072 HOH C O 1 HETATM 5034 O O . HOH HA 6 . ? 67.469 64.556 -24.597 1.00 63.45 ? 2073 HOH C O 1 HETATM 5035 O O . HOH HA 6 . ? 69.722 47.778 -21.044 1.00 33.28 ? 2074 HOH C O 1 HETATM 5036 O O . HOH HA 6 . ? 74.097 53.265 -22.455 1.00 34.82 ? 2075 HOH C O 1 HETATM 5037 O O . HOH HA 6 . ? 72.463 51.807 -25.189 1.00 54.65 ? 2076 HOH C O 1 HETATM 5038 O O . HOH HA 6 . ? 68.728 54.829 -25.098 1.00 52.02 ? 2077 HOH C O 1 HETATM 5039 O O . HOH HA 6 . ? 73.794 55.710 -20.159 1.00 69.65 ? 2078 HOH C O 1 HETATM 5040 O O . HOH HA 6 . ? 63.229 52.591 -28.880 1.00 63.91 ? 2079 HOH C O 1 HETATM 5041 O O . HOH HA 6 . ? 56.780 50.289 -27.235 1.00 34.40 ? 2080 HOH C O 1 HETATM 5042 O O . HOH HA 6 . ? 57.591 58.685 -34.096 1.00 60.15 ? 2081 HOH C O 1 HETATM 5043 O O . HOH HA 6 . ? 61.358 39.699 5.030 1.00 49.06 ? 2082 HOH C O 1 HETATM 5044 O O . HOH HA 6 . ? 47.436 56.731 -38.431 1.00 62.90 ? 2083 HOH C O 1 HETATM 5045 O O . HOH HA 6 . ? 46.887 64.062 -37.042 1.00 70.75 ? 2084 HOH C O 1 HETATM 5046 O O . HOH HA 6 . ? 77.590 21.928 25.427 1.00 72.91 ? 2085 HOH C O 1 HETATM 5047 O O . HOH HA 6 . ? 50.486 54.547 -39.216 1.00 71.80 ? 2086 HOH C O 1 HETATM 5048 O O . HOH HA 6 . ? 83.545 32.614 18.513 1.00 56.55 ? 2087 HOH C O 1 HETATM 5049 O O . HOH HA 6 . ? 49.006 50.543 -36.644 1.00 73.47 ? 2088 HOH C O 1 HETATM 5050 O O . HOH HA 6 . ? 79.893 31.808 11.613 1.00 53.69 ? 2089 HOH C O 1 HETATM 5051 O O . HOH HA 6 . ? 56.967 54.891 -32.685 1.00 52.89 ? 2090 HOH C O 1 HETATM 5052 O O . HOH HA 6 . ? 59.929 56.836 -31.827 1.00 66.64 ? 2091 HOH C O 1 HETATM 5053 O O . HOH HA 6 . ? 62.968 55.967 -29.494 1.00 58.81 ? 2092 HOH C O 1 HETATM 5054 O O . HOH HA 6 . ? 74.075 49.700 9.079 1.00 45.22 ? 2093 HOH C O 1 HETATM 5055 O O . HOH HA 6 . ? 75.481 44.347 18.937 1.00 65.67 ? 2094 HOH C O 1 HETATM 5056 O O . HOH HA 6 . ? 62.566 48.683 -32.366 1.00 54.31 ? 2095 HOH C O 1 HETATM 5057 O O . HOH HA 6 . ? 59.733 46.773 -24.329 1.00 34.49 ? 2096 HOH C O 1 HETATM 5058 O O . HOH HA 6 . ? 68.314 52.516 -27.053 1.00 46.44 ? 2097 HOH C O 1 HETATM 5059 O O . HOH HA 6 . ? 84.095 36.717 17.352 1.00 59.76 ? 2098 HOH C O 1 HETATM 5060 O O . HOH HA 6 . ? 82.730 35.092 20.063 1.00 49.44 ? 2099 HOH C O 1 HETATM 5061 O O . HOH HA 6 . ? 61.900 43.992 -21.926 1.00 25.32 ? 2100 HOH C O 1 HETATM 5062 O O . HOH HA 6 . ? 83.567 36.972 14.635 1.00 45.66 ? 2101 HOH C O 1 HETATM 5063 O O . HOH HA 6 . ? 66.478 39.959 -25.786 1.00 33.65 ? 2102 HOH C O 1 HETATM 5064 O O . HOH HA 6 . ? 83.381 39.582 5.843 1.00 64.98 ? 2103 HOH C O 1 HETATM 5065 O O . HOH HA 6 . ? 63.743 39.613 -26.513 1.00 37.37 ? 2104 HOH C O 1 HETATM 5066 O O . HOH HA 6 . ? 67.769 41.197 -19.082 1.00 33.18 ? 2105 HOH C O 1 HETATM 5067 O O . HOH HA 6 . ? 61.099 40.432 -21.593 1.00 41.47 ? 2106 HOH C O 1 HETATM 5068 O O . HOH HA 6 . ? 56.541 44.138 -18.090 1.00 42.52 ? 2107 HOH C O 1 HETATM 5069 O O . HOH HA 6 . ? 57.037 41.703 -19.343 1.00 45.93 ? 2108 HOH C O 1 HETATM 5070 O O . HOH HA 6 . ? 62.700 40.605 -14.554 1.00 37.23 ? 2109 HOH C O 1 HETATM 5071 O O . HOH HA 6 . ? 54.708 46.622 -24.602 1.00 40.44 ? 2110 HOH C O 1 HETATM 5072 O O . HOH HA 6 . ? 51.480 44.429 -19.910 1.00 62.65 ? 2111 HOH C O 1 HETATM 5073 O O . HOH HA 6 . ? 59.877 33.745 -20.884 1.00 63.98 ? 2112 HOH C O 1 HETATM 5074 O O . HOH HA 6 . ? 50.197 52.855 -21.005 1.00 35.91 ? 2113 HOH C O 1 HETATM 5075 O O . HOH HA 6 . ? 47.726 52.737 -19.793 1.00 66.44 ? 2114 HOH C O 1 HETATM 5076 O O . HOH HA 6 . ? 45.818 47.802 -24.121 1.00 61.63 ? 2115 HOH C O 1 HETATM 5077 O O . HOH HA 6 . ? 46.555 54.908 -21.326 1.00 45.11 ? 2116 HOH C O 1 HETATM 5078 O O . HOH HA 6 . ? 62.539 42.311 19.330 1.00 54.43 ? 2117 HOH C O 1 HETATM 5079 O O . HOH HA 6 . ? 67.778 48.924 18.296 1.00 60.52 ? 2118 HOH C O 1 HETATM 5080 O O . HOH HA 6 . ? 65.378 49.946 9.432 1.00 51.91 ? 2119 HOH C O 1 HETATM 5081 O O . HOH HA 6 . ? 66.346 52.356 4.729 1.00 56.38 ? 2120 HOH C O 1 HETATM 5082 O O . HOH HA 6 . ? 47.836 52.278 -17.290 1.00 56.01 ? 2121 HOH C O 1 HETATM 5083 O O . HOH HA 6 . ? 48.017 52.043 -12.272 1.00 66.90 ? 2122 HOH C O 1 HETATM 5084 O O . HOH HA 6 . ? 68.522 40.631 -9.722 1.00 38.33 ? 2123 HOH C O 1 HETATM 5085 O O . HOH HA 6 . ? 69.670 41.750 -11.865 1.00 34.94 ? 2124 HOH C O 1 HETATM 5086 O O . HOH HA 6 . ? 71.879 47.259 -9.800 1.00 53.71 ? 2125 HOH C O 1 HETATM 5087 O O . HOH HA 6 . ? 70.368 43.637 -18.531 1.00 34.36 ? 2126 HOH C O 1 HETATM 5088 O O . HOH HA 6 . ? 73.746 49.481 -5.988 1.00 51.58 ? 2127 HOH C O 1 HETATM 5089 O O . HOH HA 6 . ? 70.998 52.259 -3.817 1.00 70.71 ? 2128 HOH C O 1 HETATM 5090 O O . HOH HA 6 . ? 68.206 54.875 -8.875 1.00 47.88 ? 2129 HOH C O 1 HETATM 5091 O O . HOH HA 6 . ? 66.273 62.530 -16.939 1.00 44.41 ? 2130 HOH C O 1 HETATM 5092 O O . HOH HA 6 . ? 60.667 62.849 -26.933 1.00 45.11 ? 2131 HOH C O 1 HETATM 5093 O O . HOH HA 6 . ? 64.677 60.950 -27.274 1.00 55.05 ? 2132 HOH C O 1 HETATM 5094 O O . HOH HA 6 . ? 66.139 62.492 -25.496 1.00 60.47 ? 2133 HOH C O 1 HETATM 5095 O O . HOH HA 6 . ? 56.086 69.727 -30.125 1.00 57.29 ? 2134 HOH C O 1 HETATM 5096 O O . HOH HA 6 . ? 47.087 76.906 -28.916 1.00 69.74 ? 2135 HOH C O 1 HETATM 5097 O O . HOH HA 6 . ? 60.272 65.516 -25.750 1.00 56.76 ? 2136 HOH C O 1 HETATM 5098 O O . HOH HA 6 . ? 60.540 66.110 -22.801 1.00 44.70 ? 2137 HOH C O 1 HETATM 5099 O O . HOH HA 6 . ? 64.682 38.120 -0.028 1.00 48.61 ? 2138 HOH C O 1 HETATM 5100 O O . HOH HA 6 . ? 68.344 38.335 0.604 1.00 29.96 ? 2139 HOH C O 1 HETATM 5101 O O . HOH HA 6 . ? 63.339 37.832 4.261 1.00 63.00 ? 2140 HOH C O 1 HETATM 5102 O O . HOH HA 6 . ? 62.255 37.401 0.888 1.00 51.52 ? 2141 HOH C O 1 HETATM 5103 O O . HOH HA 6 . ? 63.416 34.950 11.740 1.00 31.31 ? 2142 HOH C O 1 HETATM 5104 O O . HOH HA 6 . ? 77.413 26.133 15.474 1.00 73.45 ? 2143 HOH C O 1 HETATM 5105 O O . HOH HA 6 . ? 76.210 28.468 22.605 1.00 35.09 ? 2144 HOH C O 1 HETATM 5106 O O . HOH HA 6 . ? 84.249 21.947 14.223 1.00 76.08 ? 2145 HOH C O 1 HETATM 5107 O O . HOH HA 6 . ? 79.876 24.278 23.861 1.00 61.93 ? 2146 HOH C O 1 HETATM 5108 O O . HOH HA 6 . ? 81.706 30.893 28.528 1.00 54.96 ? 2147 HOH C O 1 HETATM 5109 O O . HOH HA 6 . ? 79.656 26.291 27.770 1.00 62.32 ? 2148 HOH C O 1 HETATM 5110 O O . HOH HA 6 . ? 75.422 28.183 28.789 1.00 50.63 ? 2149 HOH C O 1 HETATM 5111 O O . HOH HA 6 . ? 81.056 31.078 17.109 1.00 50.76 ? 2150 HOH C O 1 HETATM 5112 O O . HOH HA 6 . ? 79.433 33.968 10.304 1.00 41.80 ? 2151 HOH C O 1 HETATM 5113 O O . HOH HA 6 . ? 71.979 42.548 5.178 1.00 21.98 ? 2152 HOH C O 1 HETATM 5114 O O . HOH HA 6 . ? 70.257 39.020 -2.491 1.00 23.55 ? 2153 HOH C O 1 HETATM 5115 O O . HOH HA 6 . ? 69.064 50.795 -1.420 1.00 34.22 ? 2154 HOH C O 1 HETATM 5116 O O . HOH HA 6 . ? 73.308 49.814 3.377 1.00 44.31 ? 2155 HOH C O 1 HETATM 5117 O O . HOH HA 6 . ? 68.529 48.540 7.466 1.00 38.76 ? 2156 HOH C O 1 HETATM 5118 O O . HOH HA 6 . ? 71.386 50.198 6.460 1.00 47.79 ? 2157 HOH C O 1 HETATM 5119 O O . HOH HA 6 . ? 74.768 47.121 9.205 1.00 49.74 ? 2158 HOH C O 1 HETATM 5120 O O . HOH HA 6 . ? 68.450 45.637 14.885 1.00 28.02 ? 2159 HOH C O 1 HETATM 5121 O O . HOH HA 6 . ? 74.337 45.745 12.347 1.00 25.12 ? 2160 HOH C O 1 HETATM 5122 O O . HOH HA 6 . ? 75.808 44.354 16.265 1.00 46.64 ? 2161 HOH C O 1 HETATM 5123 O O . HOH HA 6 . ? 72.826 47.284 16.009 1.00 42.08 ? 2162 HOH C O 1 HETATM 5124 O O . HOH HA 6 . ? 67.353 44.565 20.023 1.00 42.69 ? 2163 HOH C O 1 HETATM 5125 O O . HOH HA 6 . ? 73.135 44.899 20.130 1.00 38.42 ? 2164 HOH C O 1 HETATM 5126 O O . HOH HA 6 . ? 69.310 45.568 21.991 1.00 49.40 ? 2165 HOH C O 1 HETATM 5127 O O . HOH HA 6 . ? 66.526 37.155 25.552 1.00 41.97 ? 2166 HOH C O 1 HETATM 5128 O O . HOH HA 6 . ? 66.831 41.936 20.359 1.00 32.08 ? 2167 HOH C O 1 HETATM 5129 O O . HOH HA 6 . ? 67.152 45.578 24.045 1.00 74.42 ? 2168 HOH C O 1 HETATM 5130 O O . HOH HA 6 . ? 75.133 39.930 29.940 1.00 54.01 ? 2169 HOH C O 1 HETATM 5131 O O . HOH HA 6 . ? 74.888 43.757 22.343 1.00 51.77 ? 2170 HOH C O 1 HETATM 5132 O O . HOH HA 6 . ? 82.545 37.624 19.478 1.00 49.22 ? 2171 HOH C O 1 HETATM 5133 O O . HOH HA 6 . ? 83.718 39.214 21.097 1.00 48.67 ? 2172 HOH C O 1 HETATM 5134 O O . HOH HA 6 . ? 79.240 39.847 27.995 1.00 46.91 ? 2173 HOH C O 1 HETATM 5135 O O . HOH HA 6 . ? 83.530 37.745 24.766 1.00 61.87 ? 2174 HOH C O 1 HETATM 5136 O O . HOH HA 6 . ? 79.029 44.136 17.234 1.00 37.40 ? 2175 HOH C O 1 HETATM 5137 O O . HOH HA 6 . ? 80.836 37.502 12.969 1.00 40.50 ? 2176 HOH C O 1 HETATM 5138 O O . HOH HA 6 . ? 80.145 39.432 6.655 1.00 39.90 ? 2177 HOH C O 1 HETATM 5139 O O . HOH HA 6 . ? 84.454 42.417 6.621 1.00 47.91 ? 2178 HOH C O 1 HETATM 5140 O O . HOH HA 6 . ? 76.434 47.513 6.948 1.00 60.50 ? 2179 HOH C O 1 HETATM 5141 O O . HOH HA 6 . ? 79.732 37.713 4.134 1.00 52.41 ? 2180 HOH C O 1 HETATM 5142 O O . HOH HA 6 . ? 81.122 39.665 -2.355 1.00 36.55 ? 2181 HOH C O 1 HETATM 5143 O O . HOH HA 6 . ? 82.041 45.372 -3.389 1.00 59.67 ? 2182 HOH C O 1 HETATM 5144 O O . HOH HA 6 . ? 77.057 46.779 -1.524 1.00 42.47 ? 2183 HOH C O 1 HETATM 5145 O O . HOH HA 6 . ? 78.095 47.944 -3.797 1.00 71.34 ? 2184 HOH C O 1 HETATM 5146 O O . HOH HA 6 . ? 76.021 36.476 0.779 1.00 31.69 ? 2185 HOH C O 1 HETATM 5147 O O . HOH HA 6 . ? 76.169 44.649 -10.450 1.00 44.36 ? 2186 HOH C O 1 HETATM 5148 O O . HOH HA 6 . ? 75.101 47.244 -8.918 1.00 65.15 ? 2187 HOH C O 1 HETATM 5149 O O . HOH HA 6 . ? 76.747 48.532 -6.571 1.00 65.59 ? 2188 HOH C O 1 HETATM 5150 O O . HOH HA 6 . ? 73.476 44.329 -9.719 1.00 57.55 ? 2189 HOH C O 1 HETATM 5151 O O . HOH HA 6 . ? 72.269 47.441 -7.130 1.00 53.73 ? 2190 HOH C O 1 HETATM 5152 O O . HOH HA 6 . ? 75.261 38.664 -8.025 1.00 26.00 ? 2191 HOH C O 1 HETATM 5153 O O . HOH HA 6 . ? 73.725 49.949 -2.692 1.00 58.54 ? 2192 HOH C O 1 HETATM 5154 O O . HOH HA 6 . ? 73.102 48.366 0.083 1.00 40.73 ? 2193 HOH C O 1 HETATM 5155 O O . HOH HA 6 . ? 76.103 30.753 5.357 1.00 79.18 ? 2194 HOH C O 1 HETATM 5156 O O . HOH HA 6 . ? 78.713 32.529 2.519 1.00 52.87 ? 2195 HOH C O 1 HETATM 5157 O O . HOH HA 6 . ? 80.943 32.602 14.431 1.00 68.43 ? 2196 HOH C O 1 HETATM 5158 O O . HOH HA 6 . ? 77.655 38.819 29.750 1.00 56.30 ? 2197 HOH C O 1 HETATM 5159 O O . HOH HA 6 . ? 74.532 41.439 36.349 1.00 60.27 ? 2198 HOH C O 1 HETATM 5160 O O . HOH HA 6 . ? 68.767 31.262 33.135 1.00 64.99 ? 2199 HOH C O 1 HETATM 5161 O O . HOH HA 6 . ? 68.133 34.132 29.776 1.00 57.83 ? 2200 HOH C O 1 HETATM 5162 O O . HOH HA 6 . ? 62.733 36.220 19.668 1.00 36.74 ? 2201 HOH C O 1 HETATM 5163 O O . HOH HA 6 . ? 63.066 38.712 19.392 1.00 60.69 ? 2202 HOH C O 1 HETATM 5164 O O . HOH HA 6 . ? 64.665 40.942 19.977 1.00 27.16 ? 2203 HOH C O 1 HETATM 5165 O O . HOH HA 6 . ? 64.814 41.636 8.613 1.00 23.60 ? 2204 HOH C O 1 HETATM 5166 O O . HOH HA 6 . ? 68.124 48.358 15.087 1.00 50.59 ? 2205 HOH C O 1 HETATM 5167 O O . HOH HA 6 . ? 60.476 47.788 9.298 1.00 43.91 ? 2206 HOH C O 1 HETATM 5168 O O . HOH HA 6 . ? 63.328 48.745 10.507 1.00 53.80 ? 2207 HOH C O 1 HETATM 5169 O O . HOH HA 6 . ? 66.544 48.860 5.982 1.00 37.01 ? 2208 HOH C O 1 HETATM 5170 O O . HOH HA 6 . ? 58.180 47.438 7.580 1.00 62.14 ? 2209 HOH C O 1 HETATM 5171 O O . HOH HA 6 . ? 60.081 49.171 2.528 1.00 57.80 ? 2210 HOH C O 1 HETATM 5172 O O . HOH HA 6 . ? 65.309 51.386 2.458 1.00 47.54 ? 2211 HOH C O 1 HETATM 5173 O O . HOH HA 6 . ? 62.705 41.832 5.633 1.00 30.98 ? 2212 HOH C O 1 HETATM 5174 O O . HOH HA 6 . ? 58.699 44.889 10.815 1.00 50.20 ? 2213 HOH C O 1 HETATM 5175 O O . HOH HA 6 . ? 60.222 41.072 14.887 1.00 46.15 ? 2214 HOH C O 1 HETATM 5176 O O . HOH HA 6 . ? 65.242 26.997 23.825 1.00 59.99 ? 2215 HOH C O 1 HETATM 5177 O O . HOH HA 6 . ? 76.423 24.519 29.070 1.00 78.14 ? 2216 HOH C O 1 HETATM 5178 O O . HOH HA 6 . ? 51.869 48.186 -34.066 1.00 53.21 ? 2217 HOH C O 1 HETATM 5179 O O . HOH HA 6 . ? 66.321 38.112 -17.141 1.00 42.95 ? 2218 HOH C O 1 HETATM 5180 O O . HOH HA 6 . ? 60.439 36.465 -21.385 1.00 58.44 ? 2219 HOH C O 1 HETATM 5181 O O . HOH HA 6 . ? 61.396 32.599 -18.775 1.00 70.73 ? 2220 HOH C O 1 HETATM 5182 O O . HOH HA 6 . ? 42.263 59.453 -17.988 1.00 60.52 ? 2221 HOH C O 1 HETATM 5183 O O . HOH HA 6 . ? 44.136 52.240 -21.520 1.00 73.31 ? 2222 HOH C O 1 HETATM 5184 O O . HOH HA 6 . ? 59.562 42.418 -22.202 1.00 46.30 ? 2223 HOH C O 1 HETATM 5185 O O . HOH HA 6 . ? 69.711 48.017 26.013 1.00 53.77 ? 2224 HOH C O 1 HETATM 5186 O O . HOH HA 6 . ? 70.676 49.387 28.529 1.00 45.78 ? 2225 HOH C O 1 HETATM 5187 O O . HOH HA 6 . ? 4.598 54.320 39.815 1.00 63.61 ? 2226 HOH C O 1 HETATM 5188 O O . HOH HA 6 . ? 1.786 56.146 17.007 1.00 84.51 ? 2227 HOH C O 1 HETATM 5189 O O . HOH HA 6 . ? 52.755 42.344 6.740 1.00 70.54 ? 2228 HOH C O 1 HETATM 5190 O O . HOH HA 6 . ? 59.941 69.978 -1.764 1.00 66.87 ? 2229 HOH C O 1 HETATM 5191 O O . HOH HA 6 . ? 56.762 28.888 -4.440 1.00 63.49 ? 2230 HOH C O 1 HETATM 5192 O O . HOH HA 6 . ? 32.518 38.366 8.771 1.00 71.56 ? 2231 HOH C O 1 HETATM 5193 O O . HOH HA 6 . ? 32.737 56.302 -17.372 1.00 78.44 ? 2232 HOH C O 1 HETATM 5194 O O . HOH HA 6 . ? 41.917 60.037 -31.154 1.00 68.49 ? 2233 HOH C O 1 HETATM 5195 O O . HOH HA 6 . ? 37.329 28.060 5.419 1.00 57.15 ? 2234 HOH C O 1 HETATM 5196 O O . HOH HA 6 . ? 44.592 34.540 -0.907 1.00 77.18 ? 2235 HOH C O 1 HETATM 5197 O O . HOH HA 6 . ? 45.026 32.068 -2.088 1.00 64.29 ? 2236 HOH C O 1 HETATM 5198 O O . HOH HA 6 . ? 27.430 29.050 40.716 1.00 67.32 ? 2237 HOH C O 1 HETATM 5199 O O . HOH HA 6 . ? 25.948 29.315 18.145 1.00 76.27 ? 2238 HOH C O 1 HETATM 5200 O O . HOH HA 6 . ? 48.882 5.546 12.794 1.00 74.17 ? 2239 HOH C O 1 HETATM 5201 O O . HOH HA 6 . ? 91.422 32.959 10.702 1.00 69.16 ? 2240 HOH C O 1 HETATM 5202 O O . HOH HA 6 . ? 50.711 35.079 -9.098 1.00 70.13 ? 2241 HOH C O 1 HETATM 5203 O O . HOH HA 6 . ? 35.392 47.131 -8.070 1.00 68.44 ? 2242 HOH C O 1 HETATM 5204 O O . HOH HA 6 . ? 24.875 29.969 20.818 1.00 63.71 ? 2243 HOH C O 1 HETATM 5205 O O . HOH HA 6 . ? 30.606 29.413 41.915 1.00 60.05 ? 2244 HOH C O 1 HETATM 5206 O O . HOH HA 6 . ? 82.182 56.054 -13.471 1.00 67.48 ? 2245 HOH C O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 THR 1 2 ? ? ? A . n A 1 2 ASP 2 3 ? ? ? A . n A 1 3 GLU 3 4 ? ? ? A . n A 1 4 ASN 4 5 ? ? ? A . n A 1 5 GLN 5 6 ? ? ? A . n A 1 6 THR 6 7 ? ? ? A . n A 1 7 ILE 7 8 ? ? ? A . n A 1 8 GLN 8 9 ? ? ? A . n A 1 9 ASN 9 10 ? ? ? A . n A 1 10 ASP 10 11 ? ? ? A . n A 1 11 SER 11 12 ? ? ? A . n A 1 12 SER 12 13 ? ? ? A . n A 1 13 SER 13 14 ? ? ? A . n A 1 14 SER 14 15 ? ? ? A . n A 1 15 LEU 15 16 ? ? ? A . n A 1 16 THR 16 17 ? ? ? A . n A 1 17 GLN 17 18 18 GLN GLN A . n A 1 18 VAL 18 19 19 VAL VAL A . n A 1 19 ASN 19 20 20 ASN ASN A . n A 1 20 THR 20 21 21 THR THR A . n A 1 21 THR 21 22 22 THR THR A . n A 1 22 MET 22 23 23 MET MET A . n A 1 23 SER 23 24 24 SER SER A . n A 1 24 VAL 24 25 25 VAL VAL A . n A 1 25 GLN 25 26 26 GLN GLN A . n A 1 26 MET 26 27 27 MET MET A . n A 1 27 ASP 27 28 28 ASP ASP A . n A 1 28 LYS 28 29 29 LYS LYS A . n A 1 29 LYS 29 30 30 LYS LYS A . n A 1 30 ALA 30 31 31 ALA ALA A . n A 1 31 LEU 31 32 32 LEU LEU A . n A 1 32 LEU 32 33 33 LEU LEU A . n A 1 33 CYS 33 34 34 CYS CYS A . n A 1 34 CYS 34 35 35 CYS CYS A . n A 1 35 PHE 35 36 36 PHE PHE A . n A 1 36 SER 36 37 37 SER SER A . n A 1 37 SER 37 38 38 SER SER A . n A 1 38 PRO 38 39 39 PRO PRO A . n A 1 39 LEU 39 40 40 LEU LEU A . n A 1 40 ILE 40 41 41 ILE ILE A . n A 1 41 ASN 41 42 42 ASN ASN A . n A 1 42 ALA 42 43 43 ALA ALA A . n A 1 43 VAL 43 44 44 VAL VAL A . n A 1 44 LEU 44 45 45 LEU LEU A . n A 1 45 ILE 45 46 46 ILE ILE A . n A 1 46 THR 46 47 47 THR THR A . n A 1 47 TRP 47 48 48 TRP TRP A . n A 1 48 ILE 48 49 49 ILE ILE A . n A 1 49 ILE 49 50 50 ILE ILE A . n A 1 50 LYS 50 51 51 LYS LYS A . n A 1 51 HIS 51 52 52 HIS HIS A . n A 1 52 ARG 52 53 53 ARG ARG A . n A 1 53 HIS 53 54 54 HIS HIS A . n A 1 54 LEU 54 55 55 LEU LEU A . n A 1 55 PRO 55 56 56 PRO PRO A . n A 1 56 SER 56 57 57 SER SER A . n A 1 57 CYS 57 58 58 CYS CYS A . n A 1 58 THR 58 59 59 THR THR A . n A 1 59 ILE 59 60 60 ILE ILE A . n A 1 60 ALA 60 61 61 ALA ALA A . n A 1 61 TYR 61 62 62 TYR TYR A . n A 1 62 ASN 62 63 63 ASN ASN A . n A 1 63 LEU 63 64 64 LEU LEU A . n A 1 64 ASP 64 65 65 ASP ASP A . n A 1 65 LYS 65 66 66 LYS LYS A . n A 1 66 LYS 66 67 67 LYS LYS A . n A 1 67 THR 67 68 68 THR THR A . n A 1 68 ASN 68 69 69 ASN ASN A . n A 1 69 GLU 69 70 70 GLU GLU A . n A 1 70 THR 70 71 71 THR THR A . n A 1 71 SER 71 72 72 SER SER A . n A 1 72 CYS 72 73 73 CYS CYS A . n A 1 73 LEU 73 74 74 LEU LEU A . n A 1 74 GLY 74 75 75 GLY GLY A . n A 1 75 ARG 75 76 76 ARG ARG A . n A 1 76 ASN 76 77 77 ASN ASN A . n A 1 77 ILE 77 78 78 ILE ILE A . n A 1 78 THR 78 79 79 THR THR A . n A 1 79 TRP 79 80 80 TRP TRP A . n A 1 80 ALA 80 81 81 ALA ALA A . n A 1 81 SER 81 82 82 SER SER A . n A 1 82 THR 82 83 83 THR THR A . n A 1 83 PRO 83 84 84 PRO PRO A . n A 1 84 ASP 84 85 85 ASP ASP A . n A 1 85 HIS 85 86 86 HIS HIS A . n A 1 86 SER 86 87 87 SER SER A . n A 1 87 PRO 87 88 88 PRO PRO A . n A 1 88 GLU 88 89 89 GLU GLU A . n A 1 89 LEU 89 90 90 LEU LEU A . n A 1 90 GLN 90 91 91 GLN GLN A . n A 1 91 ILE 91 92 92 ILE ILE A . n A 1 92 SER 92 93 93 SER SER A . n A 1 93 ALA 93 94 94 ALA ALA A . n A 1 94 VAL 94 95 95 VAL VAL A . n A 1 95 ALA 95 96 96 ALA ALA A . n A 1 96 LEU 96 97 97 LEU LEU A . n A 1 97 GLN 97 98 98 GLN GLN A . n A 1 98 HIS 98 99 99 HIS HIS A . n A 1 99 GLU 99 100 100 GLU GLU A . n A 1 100 GLY 100 101 101 GLY GLY A . n A 1 101 THR 101 102 102 THR THR A . n A 1 102 TYR 102 103 103 TYR TYR A . n A 1 103 THR 103 104 104 THR THR A . n A 1 104 CYS 104 105 105 CYS CYS A . n A 1 105 GLU 105 106 106 GLU GLU A . n A 1 106 ILE 106 107 107 ILE ILE A . n A 1 107 VAL 107 108 108 VAL VAL A . n A 1 108 THR 108 109 109 THR THR A . n A 1 109 PRO 109 110 110 PRO PRO A . n A 1 110 GLU 110 111 111 GLU GLU A . n A 1 111 GLY 111 112 112 GLY GLY A . n A 1 112 ASN 112 113 113 ASN ASN A . n A 1 113 LEU 113 114 114 LEU LEU A . n A 1 114 GLU 114 115 115 GLU GLU A . n A 1 115 LYS 115 116 116 LYS LYS A . n A 1 116 VAL 116 117 117 VAL VAL A . n A 1 117 TYR 117 118 118 TYR TYR A . n A 1 118 ASP 118 119 119 ASP ASP A . n A 1 119 LEU 119 120 120 LEU LEU A . n A 1 120 GLN 120 121 121 GLN GLN A . n A 1 121 VAL 121 122 122 VAL VAL A . n A 1 122 LEU 122 123 123 LEU LEU A . n A 1 123 VAL 123 124 124 VAL VAL A . n A 1 124 PRO 124 125 125 PRO PRO A . n A 1 125 PRO 125 126 126 PRO PRO A . n A 1 126 GLU 126 127 127 GLU GLU A . n A 1 127 VAL 127 128 128 VAL VAL A . n A 1 128 THR 128 129 129 THR THR A . n A 1 129 TYR 129 130 130 TYR TYR A . n A 1 130 PHE 130 131 131 PHE PHE A . n A 1 131 PRO 131 132 132 PRO PRO A . n A 1 132 GLY 132 133 133 GLY GLY A . n A 1 133 LYS 133 134 134 LYS LYS A . n A 1 134 ASN 134 135 135 ASN ASN A . n A 1 135 ARG 135 136 136 ARG ARG A . n A 1 136 THR 136 137 137 THR THR A . n A 1 137 ALA 137 138 138 ALA ALA A . n A 1 138 VAL 138 139 139 VAL VAL A . n A 1 139 CYS 139 140 140 CYS CYS A . n A 1 140 GLU 140 141 141 GLU GLU A . n A 1 141 ALA 141 142 142 ALA ALA A . n A 1 142 MET 142 143 143 MET MET A . n A 1 143 ALA 143 144 144 ALA ALA A . n A 1 144 GLY 144 145 145 GLY GLY A . n A 1 145 LYS 145 146 146 LYS LYS A . n A 1 146 PRO 146 147 147 PRO PRO A . n A 1 147 ALA 147 148 148 ALA ALA A . n A 1 148 ALA 148 149 149 ALA ALA A . n A 1 149 GLN 149 150 150 GLN GLN A . n A 1 150 ILE 150 151 151 ILE ILE A . n A 1 151 SER 151 152 152 SER SER A . n A 1 152 TRP 152 153 153 TRP TRP A . n A 1 153 THR 153 154 154 THR THR A . n A 1 154 PRO 154 155 155 PRO PRO A . n A 1 155 ASP 155 156 156 ASP ASP A . n A 1 156 GLY 156 157 157 GLY GLY A . n A 1 157 ASP 157 158 158 ASP ASP A . n A 1 158 CYS 158 159 159 CYS CYS A . n A 1 159 VAL 159 160 160 VAL VAL A . n A 1 160 THR 160 161 161 THR THR A . n A 1 161 LYS 161 162 162 LYS LYS A . n A 1 162 SER 162 163 163 SER SER A . n A 1 163 GLU 163 164 164 GLU GLU A . n A 1 164 SER 164 165 165 SER SER A . n A 1 165 HIS 165 166 166 HIS HIS A . n A 1 166 SER 166 167 167 SER SER A . n A 1 167 ASN 167 168 168 ASN ASN A . n A 1 168 GLY 168 169 169 GLY GLY A . n A 1 169 THR 169 170 170 THR THR A . n A 1 170 VAL 170 171 171 VAL VAL A . n A 1 171 THR 171 172 172 THR THR A . n A 1 172 VAL 172 173 173 VAL VAL A . n A 1 173 ARG 173 174 174 ARG ARG A . n A 1 174 SER 174 175 175 SER SER A . n A 1 175 THR 175 176 176 THR THR A . n A 1 176 CYS 176 177 177 CYS CYS A . n A 1 177 HIS 177 178 178 HIS HIS A . n A 1 178 TRP 178 179 179 TRP TRP A . n A 1 179 GLU 179 180 180 GLU GLU A . n A 1 180 GLN 180 181 181 GLN GLN A . n A 1 181 ASN 181 182 182 ASN ASN A . n A 1 182 ASN 182 183 183 ASN ASN A . n A 1 183 VAL 183 184 184 VAL VAL A . n A 1 184 SER 184 185 185 SER SER A . n A 1 185 VAL 185 186 186 VAL VAL A . n A 1 186 VAL 186 187 187 VAL VAL A . n A 1 187 SER 187 188 188 SER SER A . n A 1 188 CYS 188 189 189 CYS CYS A . n A 1 189 LEU 189 190 190 LEU LEU A . n A 1 190 VAL 190 191 191 VAL VAL A . n A 1 191 SER 191 192 192 SER SER A . n A 1 192 HIS 192 193 193 HIS HIS A . n A 1 193 SER 193 194 194 SER SER A . n A 1 194 THR 194 195 195 THR THR A . n A 1 195 GLY 195 196 196 GLY GLY A . n A 1 196 ASN 196 197 197 ASN ASN A . n A 1 197 GLN 197 198 198 GLN GLN A . n A 1 198 SER 198 199 199 SER SER A . n A 1 199 LEU 199 200 200 LEU LEU A . n A 1 200 SER 200 201 201 SER SER A . n A 1 201 ILE 201 202 202 ILE ILE A . n A 1 202 GLU 202 203 203 GLU GLU A . n A 1 203 LEU 203 204 204 LEU LEU A . n A 1 204 SER 204 205 205 SER SER A . n A 1 205 GLN 205 206 ? ? ? A . n A 1 206 GLY 206 207 ? ? ? A . n A 1 207 THR 207 208 ? ? ? A . n A 1 208 MET 208 209 ? ? ? A . n A 1 209 THR 209 210 ? ? ? A . n A 1 210 THR 210 211 ? ? ? A . n A 1 211 PRO 211 212 ? ? ? A . n A 1 212 ARG 212 213 ? ? ? A . n A 1 213 SER 213 214 ? ? ? A . n A 1 214 THR 214 215 ? ? ? A . n A 1 215 ARG 215 216 ? ? ? A . n A 1 216 HIS 216 217 ? ? ? A . n A 1 217 HIS 217 218 ? ? ? A . n A 1 218 HIS 218 219 ? ? ? A . n A 1 219 HIS 219 220 ? ? ? A . n A 1 220 HIS 220 221 ? ? ? A . n A 1 221 HIS 221 222 ? ? ? A . n B 1 1 THR 1 2 ? ? ? B . n B 1 2 ASP 2 3 ? ? ? B . n B 1 3 GLU 3 4 ? ? ? B . n B 1 4 ASN 4 5 ? ? ? B . n B 1 5 GLN 5 6 ? ? ? B . n B 1 6 THR 6 7 ? ? ? B . n B 1 7 ILE 7 8 ? ? ? B . n B 1 8 GLN 8 9 ? ? ? B . n B 1 9 ASN 9 10 ? ? ? B . n B 1 10 ASP 10 11 ? ? ? B . n B 1 11 SER 11 12 ? ? ? B . n B 1 12 SER 12 13 ? ? ? B . n B 1 13 SER 13 14 ? ? ? B . n B 1 14 SER 14 15 ? ? ? B . n B 1 15 LEU 15 16 ? ? ? B . n B 1 16 THR 16 17 ? ? ? B . n B 1 17 GLN 17 18 18 GLN GLN B . n B 1 18 VAL 18 19 19 VAL VAL B . n B 1 19 ASN 19 20 20 ASN ASN B . n B 1 20 THR 20 21 21 THR THR B . n B 1 21 THR 21 22 22 THR THR B . n B 1 22 MET 22 23 23 MET MET B . n B 1 23 SER 23 24 24 SER SER B . n B 1 24 VAL 24 25 25 VAL VAL B . n B 1 25 GLN 25 26 26 GLN GLN B . n B 1 26 MET 26 27 27 MET MET B . n B 1 27 ASP 27 28 28 ASP ASP B . n B 1 28 LYS 28 29 29 LYS LYS B . n B 1 29 LYS 29 30 30 LYS LYS B . n B 1 30 ALA 30 31 31 ALA ALA B . n B 1 31 LEU 31 32 32 LEU LEU B . n B 1 32 LEU 32 33 33 LEU LEU B . n B 1 33 CYS 33 34 34 CYS CYS B . n B 1 34 CYS 34 35 35 CYS CYS B . n B 1 35 PHE 35 36 36 PHE PHE B . n B 1 36 SER 36 37 37 SER SER B . n B 1 37 SER 37 38 38 SER SER B . n B 1 38 PRO 38 39 39 PRO PRO B . n B 1 39 LEU 39 40 40 LEU LEU B . n B 1 40 ILE 40 41 41 ILE ILE B . n B 1 41 ASN 41 42 42 ASN ASN B . n B 1 42 ALA 42 43 43 ALA ALA B . n B 1 43 VAL 43 44 44 VAL VAL B . n B 1 44 LEU 44 45 45 LEU LEU B . n B 1 45 ILE 45 46 46 ILE ILE B . n B 1 46 THR 46 47 47 THR THR B . n B 1 47 TRP 47 48 48 TRP TRP B . n B 1 48 ILE 48 49 49 ILE ILE B . n B 1 49 ILE 49 50 50 ILE ILE B . n B 1 50 LYS 50 51 51 LYS LYS B . n B 1 51 HIS 51 52 52 HIS HIS B . n B 1 52 ARG 52 53 53 ARG ARG B . n B 1 53 HIS 53 54 54 HIS HIS B . n B 1 54 LEU 54 55 55 LEU LEU B . n B 1 55 PRO 55 56 56 PRO PRO B . n B 1 56 SER 56 57 57 SER SER B . n B 1 57 CYS 57 58 58 CYS CYS B . n B 1 58 THR 58 59 59 THR THR B . n B 1 59 ILE 59 60 60 ILE ILE B . n B 1 60 ALA 60 61 61 ALA ALA B . n B 1 61 TYR 61 62 62 TYR TYR B . n B 1 62 ASN 62 63 63 ASN ASN B . n B 1 63 LEU 63 64 64 LEU LEU B . n B 1 64 ASP 64 65 65 ASP ASP B . n B 1 65 LYS 65 66 66 LYS LYS B . n B 1 66 LYS 66 67 67 LYS LYS B . n B 1 67 THR 67 68 68 THR THR B . n B 1 68 ASN 68 69 69 ASN ASN B . n B 1 69 GLU 69 70 70 GLU GLU B . n B 1 70 THR 70 71 71 THR THR B . n B 1 71 SER 71 72 72 SER SER B . n B 1 72 CYS 72 73 73 CYS CYS B . n B 1 73 LEU 73 74 74 LEU LEU B . n B 1 74 GLY 74 75 75 GLY GLY B . n B 1 75 ARG 75 76 76 ARG ARG B . n B 1 76 ASN 76 77 77 ASN ASN B . n B 1 77 ILE 77 78 78 ILE ILE B . n B 1 78 THR 78 79 79 THR THR B . n B 1 79 TRP 79 80 80 TRP TRP B . n B 1 80 ALA 80 81 81 ALA ALA B . n B 1 81 SER 81 82 82 SER SER B . n B 1 82 THR 82 83 83 THR THR B . n B 1 83 PRO 83 84 84 PRO PRO B . n B 1 84 ASP 84 85 85 ASP ASP B . n B 1 85 HIS 85 86 86 HIS HIS B . n B 1 86 SER 86 87 87 SER SER B . n B 1 87 PRO 87 88 88 PRO PRO B . n B 1 88 GLU 88 89 89 GLU GLU B . n B 1 89 LEU 89 90 90 LEU LEU B . n B 1 90 GLN 90 91 91 GLN GLN B . n B 1 91 ILE 91 92 92 ILE ILE B . n B 1 92 SER 92 93 93 SER SER B . n B 1 93 ALA 93 94 94 ALA ALA B . n B 1 94 VAL 94 95 95 VAL VAL B . n B 1 95 ALA 95 96 96 ALA ALA B . n B 1 96 LEU 96 97 97 LEU LEU B . n B 1 97 GLN 97 98 98 GLN GLN B . n B 1 98 HIS 98 99 99 HIS HIS B . n B 1 99 GLU 99 100 100 GLU GLU B . n B 1 100 GLY 100 101 101 GLY GLY B . n B 1 101 THR 101 102 102 THR THR B . n B 1 102 TYR 102 103 103 TYR TYR B . n B 1 103 THR 103 104 104 THR THR B . n B 1 104 CYS 104 105 105 CYS CYS B . n B 1 105 GLU 105 106 106 GLU GLU B . n B 1 106 ILE 106 107 107 ILE ILE B . n B 1 107 VAL 107 108 108 VAL VAL B . n B 1 108 THR 108 109 109 THR THR B . n B 1 109 PRO 109 110 110 PRO PRO B . n B 1 110 GLU 110 111 111 GLU GLU B . n B 1 111 GLY 111 112 112 GLY GLY B . n B 1 112 ASN 112 113 113 ASN ASN B . n B 1 113 LEU 113 114 114 LEU LEU B . n B 1 114 GLU 114 115 115 GLU GLU B . n B 1 115 LYS 115 116 116 LYS LYS B . n B 1 116 VAL 116 117 117 VAL VAL B . n B 1 117 TYR 117 118 118 TYR TYR B . n B 1 118 ASP 118 119 119 ASP ASP B . n B 1 119 LEU 119 120 120 LEU LEU B . n B 1 120 GLN 120 121 121 GLN GLN B . n B 1 121 VAL 121 122 122 VAL VAL B . n B 1 122 LEU 122 123 123 LEU LEU B . n B 1 123 VAL 123 124 124 VAL VAL B . n B 1 124 PRO 124 125 125 PRO PRO B . n B 1 125 PRO 125 126 126 PRO PRO B . n B 1 126 GLU 126 127 127 GLU GLU B . n B 1 127 VAL 127 128 128 VAL VAL B . n B 1 128 THR 128 129 129 THR THR B . n B 1 129 TYR 129 130 130 TYR TYR B . n B 1 130 PHE 130 131 131 PHE PHE B . n B 1 131 PRO 131 132 132 PRO PRO B . n B 1 132 GLY 132 133 133 GLY GLY B . n B 1 133 LYS 133 134 134 LYS LYS B . n B 1 134 ASN 134 135 135 ASN ASN B . n B 1 135 ARG 135 136 136 ARG ARG B . n B 1 136 THR 136 137 137 THR THR B . n B 1 137 ALA 137 138 138 ALA ALA B . n B 1 138 VAL 138 139 139 VAL VAL B . n B 1 139 CYS 139 140 140 CYS CYS B . n B 1 140 GLU 140 141 141 GLU GLU B . n B 1 141 ALA 141 142 142 ALA ALA B . n B 1 142 MET 142 143 143 MET MET B . n B 1 143 ALA 143 144 144 ALA ALA B . n B 1 144 GLY 144 145 145 GLY GLY B . n B 1 145 LYS 145 146 146 LYS LYS B . n B 1 146 PRO 146 147 147 PRO PRO B . n B 1 147 ALA 147 148 148 ALA ALA B . n B 1 148 ALA 148 149 149 ALA ALA B . n B 1 149 GLN 149 150 150 GLN GLN B . n B 1 150 ILE 150 151 151 ILE ILE B . n B 1 151 SER 151 152 152 SER SER B . n B 1 152 TRP 152 153 153 TRP TRP B . n B 1 153 THR 153 154 154 THR THR B . n B 1 154 PRO 154 155 155 PRO PRO B . n B 1 155 ASP 155 156 156 ASP ASP B . n B 1 156 GLY 156 157 157 GLY GLY B . n B 1 157 ASP 157 158 158 ASP ASP B . n B 1 158 CYS 158 159 159 CYS CYS B . n B 1 159 VAL 159 160 160 VAL VAL B . n B 1 160 THR 160 161 161 THR THR B . n B 1 161 LYS 161 162 162 LYS LYS B . n B 1 162 SER 162 163 163 SER SER B . n B 1 163 GLU 163 164 164 GLU GLU B . n B 1 164 SER 164 165 165 SER SER B . n B 1 165 HIS 165 166 166 HIS HIS B . n B 1 166 SER 166 167 167 SER SER B . n B 1 167 ASN 167 168 168 ASN ASN B . n B 1 168 GLY 168 169 169 GLY GLY B . n B 1 169 THR 169 170 170 THR THR B . n B 1 170 VAL 170 171 171 VAL VAL B . n B 1 171 THR 171 172 172 THR THR B . n B 1 172 VAL 172 173 173 VAL VAL B . n B 1 173 ARG 173 174 174 ARG ARG B . n B 1 174 SER 174 175 175 SER SER B . n B 1 175 THR 175 176 176 THR THR B . n B 1 176 CYS 176 177 177 CYS CYS B . n B 1 177 HIS 177 178 178 HIS HIS B . n B 1 178 TRP 178 179 179 TRP TRP B . n B 1 179 GLU 179 180 180 GLU GLU B . n B 1 180 GLN 180 181 181 GLN GLN B . n B 1 181 ASN 181 182 182 ASN ASN B . n B 1 182 ASN 182 183 183 ASN ASN B . n B 1 183 VAL 183 184 184 VAL VAL B . n B 1 184 SER 184 185 185 SER SER B . n B 1 185 VAL 185 186 186 VAL VAL B . n B 1 186 VAL 186 187 187 VAL VAL B . n B 1 187 SER 187 188 188 SER SER B . n B 1 188 CYS 188 189 189 CYS CYS B . n B 1 189 LEU 189 190 190 LEU LEU B . n B 1 190 VAL 190 191 191 VAL VAL B . n B 1 191 SER 191 192 192 SER SER B . n B 1 192 HIS 192 193 193 HIS HIS B . n B 1 193 SER 193 194 194 SER SER B . n B 1 194 THR 194 195 195 THR THR B . n B 1 195 GLY 195 196 196 GLY GLY B . n B 1 196 ASN 196 197 197 ASN ASN B . n B 1 197 GLN 197 198 198 GLN GLN B . n B 1 198 SER 198 199 199 SER SER B . n B 1 199 LEU 199 200 200 LEU LEU B . n B 1 200 SER 200 201 201 SER SER B . n B 1 201 ILE 201 202 202 ILE ILE B . n B 1 202 GLU 202 203 203 GLU GLU B . n B 1 203 LEU 203 204 204 LEU LEU B . n B 1 204 SER 204 205 205 SER SER B . n B 1 205 GLN 205 206 ? ? ? B . n B 1 206 GLY 206 207 ? ? ? B . n B 1 207 THR 207 208 ? ? ? B . n B 1 208 MET 208 209 ? ? ? B . n B 1 209 THR 209 210 ? ? ? B . n B 1 210 THR 210 211 ? ? ? B . n B 1 211 PRO 211 212 ? ? ? B . n B 1 212 ARG 212 213 ? ? ? B . n B 1 213 SER 213 214 ? ? ? B . n B 1 214 THR 214 215 ? ? ? B . n B 1 215 ARG 215 216 ? ? ? B . n B 1 216 HIS 216 217 ? ? ? B . n B 1 217 HIS 217 218 ? ? ? B . n B 1 218 HIS 218 219 ? ? ? B . n B 1 219 HIS 219 220 ? ? ? B . n B 1 220 HIS 220 221 ? ? ? B . n B 1 221 HIS 221 222 ? ? ? B . n C 1 1 THR 1 2 ? ? ? C . n C 1 2 ASP 2 3 ? ? ? C . n C 1 3 GLU 3 4 ? ? ? C . n C 1 4 ASN 4 5 ? ? ? C . n C 1 5 GLN 5 6 ? ? ? C . n C 1 6 THR 6 7 ? ? ? C . n C 1 7 ILE 7 8 ? ? ? C . n C 1 8 GLN 8 9 ? ? ? C . n C 1 9 ASN 9 10 ? ? ? C . n C 1 10 ASP 10 11 ? ? ? C . n C 1 11 SER 11 12 ? ? ? C . n C 1 12 SER 12 13 ? ? ? C . n C 1 13 SER 13 14 ? ? ? C . n C 1 14 SER 14 15 ? ? ? C . n C 1 15 LEU 15 16 ? ? ? C . n C 1 16 THR 16 17 ? ? ? C . n C 1 17 GLN 17 18 ? ? ? C . n C 1 18 VAL 18 19 19 VAL VAL C . n C 1 19 ASN 19 20 20 ASN ASN C . n C 1 20 THR 20 21 21 THR THR C . n C 1 21 THR 21 22 22 THR THR C . n C 1 22 MET 22 23 23 MET MET C . n C 1 23 SER 23 24 24 SER SER C . n C 1 24 VAL 24 25 25 VAL VAL C . n C 1 25 GLN 25 26 26 GLN GLN C . n C 1 26 MET 26 27 27 MET MET C . n C 1 27 ASP 27 28 28 ASP ASP C . n C 1 28 LYS 28 29 29 LYS LYS C . n C 1 29 LYS 29 30 30 LYS LYS C . n C 1 30 ALA 30 31 31 ALA ALA C . n C 1 31 LEU 31 32 32 LEU LEU C . n C 1 32 LEU 32 33 33 LEU LEU C . n C 1 33 CYS 33 34 34 CYS CYS C . n C 1 34 CYS 34 35 35 CYS CYS C . n C 1 35 PHE 35 36 36 PHE PHE C . n C 1 36 SER 36 37 37 SER SER C . n C 1 37 SER 37 38 38 SER SER C . n C 1 38 PRO 38 39 39 PRO PRO C . n C 1 39 LEU 39 40 40 LEU LEU C . n C 1 40 ILE 40 41 41 ILE ILE C . n C 1 41 ASN 41 42 42 ASN ASN C . n C 1 42 ALA 42 43 43 ALA ALA C . n C 1 43 VAL 43 44 44 VAL VAL C . n C 1 44 LEU 44 45 45 LEU LEU C . n C 1 45 ILE 45 46 46 ILE ILE C . n C 1 46 THR 46 47 47 THR THR C . n C 1 47 TRP 47 48 48 TRP TRP C . n C 1 48 ILE 48 49 49 ILE ILE C . n C 1 49 ILE 49 50 50 ILE ILE C . n C 1 50 LYS 50 51 51 LYS LYS C . n C 1 51 HIS 51 52 52 HIS HIS C . n C 1 52 ARG 52 53 53 ARG ARG C . n C 1 53 HIS 53 54 54 HIS HIS C . n C 1 54 LEU 54 55 55 LEU LEU C . n C 1 55 PRO 55 56 56 PRO PRO C . n C 1 56 SER 56 57 57 SER SER C . n C 1 57 CYS 57 58 58 CYS CYS C . n C 1 58 THR 58 59 59 THR THR C . n C 1 59 ILE 59 60 60 ILE ILE C . n C 1 60 ALA 60 61 61 ALA ALA C . n C 1 61 TYR 61 62 62 TYR TYR C . n C 1 62 ASN 62 63 63 ASN ASN C . n C 1 63 LEU 63 64 64 LEU LEU C . n C 1 64 ASP 64 65 65 ASP ASP C . n C 1 65 LYS 65 66 66 LYS LYS C . n C 1 66 LYS 66 67 67 LYS LYS C . n C 1 67 THR 67 68 68 THR THR C . n C 1 68 ASN 68 69 69 ASN ASN C . n C 1 69 GLU 69 70 70 GLU GLU C . n C 1 70 THR 70 71 71 THR THR C . n C 1 71 SER 71 72 72 SER SER C . n C 1 72 CYS 72 73 73 CYS CYS C . n C 1 73 LEU 73 74 74 LEU LEU C . n C 1 74 GLY 74 75 75 GLY GLY C . n C 1 75 ARG 75 76 76 ARG ARG C . n C 1 76 ASN 76 77 77 ASN ASN C . n C 1 77 ILE 77 78 78 ILE ILE C . n C 1 78 THR 78 79 79 THR THR C . n C 1 79 TRP 79 80 80 TRP TRP C . n C 1 80 ALA 80 81 81 ALA ALA C . n C 1 81 SER 81 82 82 SER SER C . n C 1 82 THR 82 83 83 THR THR C . n C 1 83 PRO 83 84 84 PRO PRO C . n C 1 84 ASP 84 85 85 ASP ASP C . n C 1 85 HIS 85 86 86 HIS HIS C . n C 1 86 SER 86 87 87 SER SER C . n C 1 87 PRO 87 88 88 PRO PRO C . n C 1 88 GLU 88 89 89 GLU GLU C . n C 1 89 LEU 89 90 90 LEU LEU C . n C 1 90 GLN 90 91 91 GLN GLN C . n C 1 91 ILE 91 92 92 ILE ILE C . n C 1 92 SER 92 93 93 SER SER C . n C 1 93 ALA 93 94 94 ALA ALA C . n C 1 94 VAL 94 95 95 VAL VAL C . n C 1 95 ALA 95 96 96 ALA ALA C . n C 1 96 LEU 96 97 97 LEU LEU C . n C 1 97 GLN 97 98 98 GLN GLN C . n C 1 98 HIS 98 99 99 HIS HIS C . n C 1 99 GLU 99 100 100 GLU GLU C . n C 1 100 GLY 100 101 101 GLY GLY C . n C 1 101 THR 101 102 102 THR THR C . n C 1 102 TYR 102 103 103 TYR TYR C . n C 1 103 THR 103 104 104 THR THR C . n C 1 104 CYS 104 105 105 CYS CYS C . n C 1 105 GLU 105 106 106 GLU GLU C . n C 1 106 ILE 106 107 107 ILE ILE C . n C 1 107 VAL 107 108 108 VAL VAL C . n C 1 108 THR 108 109 109 THR THR C . n C 1 109 PRO 109 110 110 PRO PRO C . n C 1 110 GLU 110 111 111 GLU GLU C . n C 1 111 GLY 111 112 112 GLY GLY C . n C 1 112 ASN 112 113 113 ASN ASN C . n C 1 113 LEU 113 114 114 LEU LEU C . n C 1 114 GLU 114 115 115 GLU GLU C . n C 1 115 LYS 115 116 116 LYS LYS C . n C 1 116 VAL 116 117 117 VAL VAL C . n C 1 117 TYR 117 118 118 TYR TYR C . n C 1 118 ASP 118 119 119 ASP ASP C . n C 1 119 LEU 119 120 120 LEU LEU C . n C 1 120 GLN 120 121 121 GLN GLN C . n C 1 121 VAL 121 122 122 VAL VAL C . n C 1 122 LEU 122 123 123 LEU LEU C . n C 1 123 VAL 123 124 124 VAL VAL C . n C 1 124 PRO 124 125 125 PRO PRO C . n C 1 125 PRO 125 126 126 PRO PRO C . n C 1 126 GLU 126 127 127 GLU GLU C . n C 1 127 VAL 127 128 128 VAL VAL C . n C 1 128 THR 128 129 129 THR THR C . n C 1 129 TYR 129 130 130 TYR TYR C . n C 1 130 PHE 130 131 131 PHE PHE C . n C 1 131 PRO 131 132 132 PRO PRO C . n C 1 132 GLY 132 133 133 GLY GLY C . n C 1 133 LYS 133 134 134 LYS LYS C . n C 1 134 ASN 134 135 135 ASN ASN C . n C 1 135 ARG 135 136 136 ARG ARG C . n C 1 136 THR 136 137 137 THR THR C . n C 1 137 ALA 137 138 138 ALA ALA C . n C 1 138 VAL 138 139 139 VAL VAL C . n C 1 139 CYS 139 140 140 CYS CYS C . n C 1 140 GLU 140 141 141 GLU GLU C . n C 1 141 ALA 141 142 142 ALA ALA C . n C 1 142 MET 142 143 143 MET MET C . n C 1 143 ALA 143 144 144 ALA ALA C . n C 1 144 GLY 144 145 145 GLY GLY C . n C 1 145 LYS 145 146 146 LYS LYS C . n C 1 146 PRO 146 147 147 PRO PRO C . n C 1 147 ALA 147 148 148 ALA ALA C . n C 1 148 ALA 148 149 149 ALA ALA C . n C 1 149 GLN 149 150 150 GLN GLN C . n C 1 150 ILE 150 151 151 ILE ILE C . n C 1 151 SER 151 152 152 SER SER C . n C 1 152 TRP 152 153 153 TRP TRP C . n C 1 153 THR 153 154 154 THR THR C . n C 1 154 PRO 154 155 155 PRO PRO C . n C 1 155 ASP 155 156 156 ASP ASP C . n C 1 156 GLY 156 157 157 GLY GLY C . n C 1 157 ASP 157 158 158 ASP ASP C . n C 1 158 CYS 158 159 159 CYS CYS C . n C 1 159 VAL 159 160 160 VAL VAL C . n C 1 160 THR 160 161 161 THR THR C . n C 1 161 LYS 161 162 162 LYS LYS C . n C 1 162 SER 162 163 163 SER SER C . n C 1 163 GLU 163 164 164 GLU GLU C . n C 1 164 SER 164 165 165 SER SER C . n C 1 165 HIS 165 166 166 HIS HIS C . n C 1 166 SER 166 167 167 SER SER C . n C 1 167 ASN 167 168 168 ASN ASN C . n C 1 168 GLY 168 169 169 GLY GLY C . n C 1 169 THR 169 170 170 THR THR C . n C 1 170 VAL 170 171 171 VAL VAL C . n C 1 171 THR 171 172 172 THR THR C . n C 1 172 VAL 172 173 173 VAL VAL C . n C 1 173 ARG 173 174 174 ARG ARG C . n C 1 174 SER 174 175 175 SER SER C . n C 1 175 THR 175 176 176 THR THR C . n C 1 176 CYS 176 177 177 CYS CYS C . n C 1 177 HIS 177 178 178 HIS HIS C . n C 1 178 TRP 178 179 179 TRP TRP C . n C 1 179 GLU 179 180 180 GLU GLU C . n C 1 180 GLN 180 181 181 GLN GLN C . n C 1 181 ASN 181 182 182 ASN ASN C . n C 1 182 ASN 182 183 183 ASN ASN C . n C 1 183 VAL 183 184 184 VAL VAL C . n C 1 184 SER 184 185 185 SER SER C . n C 1 185 VAL 185 186 186 VAL VAL C . n C 1 186 VAL 186 187 187 VAL VAL C . n C 1 187 SER 187 188 188 SER SER C . n C 1 188 CYS 188 189 189 CYS CYS C . n C 1 189 LEU 189 190 190 LEU LEU C . n C 1 190 VAL 190 191 191 VAL VAL C . n C 1 191 SER 191 192 192 SER SER C . n C 1 192 HIS 192 193 193 HIS HIS C . n C 1 193 SER 193 194 194 SER SER C . n C 1 194 THR 194 195 195 THR THR C . n C 1 195 GLY 195 196 196 GLY GLY C . n C 1 196 ASN 196 197 197 ASN ASN C . n C 1 197 GLN 197 198 198 GLN GLN C . n C 1 198 SER 198 199 199 SER SER C . n C 1 199 LEU 199 200 200 LEU LEU C . n C 1 200 SER 200 201 201 SER SER C . n C 1 201 ILE 201 202 202 ILE ILE C . n C 1 202 GLU 202 203 203 GLU GLU C . n C 1 203 LEU 203 204 204 LEU LEU C . n C 1 204 SER 204 205 205 SER SER C . n C 1 205 GLN 205 206 ? ? ? C . n C 1 206 GLY 206 207 ? ? ? C . n C 1 207 THR 207 208 ? ? ? C . n C 1 208 MET 208 209 ? ? ? C . n C 1 209 THR 209 210 ? ? ? C . n C 1 210 THR 210 211 ? ? ? C . n C 1 211 PRO 211 212 ? ? ? C . n C 1 212 ARG 212 213 ? ? ? C . n C 1 213 SER 213 214 ? ? ? C . n C 1 214 THR 214 215 ? ? ? C . n C 1 215 ARG 215 216 ? ? ? C . n C 1 216 HIS 216 217 ? ? ? C . n C 1 217 HIS 217 218 ? ? ? C . n C 1 218 HIS 218 219 ? ? ? C . n C 1 219 HIS 219 220 ? ? ? C . n C 1 220 HIS 220 221 ? ? ? C . n C 1 221 HIS 221 222 ? ? ? C . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code D 2 NAG 1 690 690 NAG NAG A . E 2 NAG 1 770 770 NAG NAG A . F 3 CYS 1 1206 1206 CYS CYS A . G 4 SO4 1 1207 1207 SO4 SO4 A . H 4 SO4 1 1208 1208 SO4 SO4 A . I 2 NAG 1 1680 1680 NAG NAG A . J 2 NAG 1 1970 1970 NAG NAG A . K 2 NAG 1 2000 2000 NAG NAG A . L 2 NAG 1 690 690 NAG NAG B . M 2 NAG 1 770 770 NAG NAG B . N 3 CYS 1 1206 1206 CYS CYS B . O 4 SO4 1 1207 1207 SO4 SO4 B . P 4 SO4 1 1208 1208 SO4 SO4 B . Q 4 SO4 1 1209 1209 SO4 SO4 B . R 2 NAG 1 1680 1680 NAG NAG B . S 2 NAG 1 1970 1970 NAG NAG B . T 2 NAG 1 2000 2000 NAG NAG B . U 2 NAG 1 690 690 NAG NAG C . V 2 NAG 1 770 770 NAG NAG C . W 3 CYS 1 1206 1206 CYS CYS C . X 4 SO4 1 1207 1207 SO4 SO4 C . Y 4 SO4 1 1208 1208 SO4 SO4 C . Z 5 GOL 1 1209 1209 GOL GOL C . AA 5 GOL 1 1210 1210 GOL GOL C . BA 5 GOL 1 1211 1211 GOL GOL C . CA 2 NAG 1 1680 1680 NAG NAG C . DA 2 NAG 1 1970 1970 NAG NAG C . EA 2 NAG 1 2000 2000 NAG NAG C . FA 6 HOH 1 2001 2001 HOH HOH A . FA 6 HOH 2 2002 2002 HOH HOH A . FA 6 HOH 3 2003 2003 HOH HOH A . FA 6 HOH 4 2004 2004 HOH HOH A . FA 6 HOH 5 2005 2005 HOH HOH A . FA 6 HOH 6 2006 2006 HOH HOH A . FA 6 HOH 7 2007 2007 HOH HOH A . FA 6 HOH 8 2008 2008 HOH HOH A . FA 6 HOH 9 2009 2009 HOH HOH A . FA 6 HOH 10 2010 2010 HOH HOH A . FA 6 HOH 11 2011 2011 HOH HOH A . FA 6 HOH 12 2012 2012 HOH HOH A . FA 6 HOH 13 2013 2013 HOH HOH A . FA 6 HOH 14 2014 2014 HOH HOH A . FA 6 HOH 15 2015 2015 HOH HOH A . FA 6 HOH 16 2016 2016 HOH HOH A . FA 6 HOH 17 2017 2017 HOH HOH A . FA 6 HOH 18 2018 2018 HOH HOH A . FA 6 HOH 19 2019 2019 HOH HOH A . FA 6 HOH 20 2020 2020 HOH HOH A . FA 6 HOH 21 2021 2021 HOH HOH A . FA 6 HOH 22 2022 2022 HOH HOH A . FA 6 HOH 23 2023 2023 HOH HOH A . FA 6 HOH 24 2024 2024 HOH HOH A . FA 6 HOH 25 2025 2025 HOH HOH A . FA 6 HOH 26 2026 2026 HOH HOH A . FA 6 HOH 27 2027 2027 HOH HOH A . FA 6 HOH 28 2028 2028 HOH HOH A . FA 6 HOH 29 2029 2029 HOH HOH A . FA 6 HOH 30 2030 2030 HOH HOH A . FA 6 HOH 31 2031 2031 HOH HOH A . FA 6 HOH 32 2032 2032 HOH HOH A . FA 6 HOH 33 2033 2033 HOH HOH A . FA 6 HOH 34 2034 2034 HOH HOH A . FA 6 HOH 35 2035 2035 HOH HOH A . FA 6 HOH 36 2036 2036 HOH HOH A . FA 6 HOH 37 2037 2037 HOH HOH A . FA 6 HOH 38 2038 2038 HOH HOH A . FA 6 HOH 39 2039 2039 HOH HOH A . FA 6 HOH 40 2040 2040 HOH HOH A . FA 6 HOH 41 2041 2041 HOH HOH A . FA 6 HOH 42 2042 2042 HOH HOH A . FA 6 HOH 43 2043 2043 HOH HOH A . FA 6 HOH 44 2044 2044 HOH HOH A . FA 6 HOH 45 2045 2045 HOH HOH A . FA 6 HOH 46 2046 2046 HOH HOH A . FA 6 HOH 47 2047 2047 HOH HOH A . FA 6 HOH 48 2048 2048 HOH HOH A . FA 6 HOH 49 2049 2049 HOH HOH A . FA 6 HOH 50 2050 2050 HOH HOH A . FA 6 HOH 51 2051 2051 HOH HOH A . FA 6 HOH 52 2052 2052 HOH HOH A . FA 6 HOH 53 2053 2053 HOH HOH A . FA 6 HOH 54 2054 2054 HOH HOH A . FA 6 HOH 55 2055 2055 HOH HOH A . FA 6 HOH 56 2056 2056 HOH HOH A . FA 6 HOH 57 2057 2057 HOH HOH A . FA 6 HOH 58 2058 2058 HOH HOH A . FA 6 HOH 59 2059 2059 HOH HOH A . FA 6 HOH 60 2060 2060 HOH HOH A . FA 6 HOH 61 2061 2061 HOH HOH A . FA 6 HOH 62 2062 2062 HOH HOH A . FA 6 HOH 63 2063 2063 HOH HOH A . FA 6 HOH 64 2064 2064 HOH HOH A . FA 6 HOH 65 2065 2065 HOH HOH A . FA 6 HOH 66 2066 2066 HOH HOH A . FA 6 HOH 67 2067 2067 HOH HOH A . FA 6 HOH 68 2068 2068 HOH HOH A . FA 6 HOH 69 2069 2069 HOH HOH A . FA 6 HOH 70 2070 2070 HOH HOH A . FA 6 HOH 71 2071 2071 HOH HOH A . FA 6 HOH 72 2072 2072 HOH HOH A . FA 6 HOH 73 2073 2073 HOH HOH A . FA 6 HOH 74 2074 2074 HOH HOH A . FA 6 HOH 75 2075 2075 HOH HOH A . FA 6 HOH 76 2076 2076 HOH HOH A . FA 6 HOH 77 2077 2077 HOH HOH A . FA 6 HOH 78 2078 2078 HOH HOH A . FA 6 HOH 79 2079 2079 HOH HOH A . FA 6 HOH 80 2080 2080 HOH HOH A . FA 6 HOH 81 2081 2081 HOH HOH A . FA 6 HOH 82 2082 2082 HOH HOH A . FA 6 HOH 83 2083 2083 HOH HOH A . FA 6 HOH 84 2084 2084 HOH HOH A . FA 6 HOH 85 2085 2085 HOH HOH A . FA 6 HOH 86 2086 2086 HOH HOH A . FA 6 HOH 87 2087 2087 HOH HOH A . FA 6 HOH 88 2088 2088 HOH HOH A . FA 6 HOH 89 2089 2089 HOH HOH A . FA 6 HOH 90 2090 2090 HOH HOH A . FA 6 HOH 91 2091 2091 HOH HOH A . FA 6 HOH 92 2092 2092 HOH HOH A . FA 6 HOH 93 2093 2093 HOH HOH A . FA 6 HOH 94 2094 2094 HOH HOH A . FA 6 HOH 95 2095 2095 HOH HOH A . FA 6 HOH 96 2096 2096 HOH HOH A . FA 6 HOH 97 2097 2097 HOH HOH A . FA 6 HOH 98 2098 2098 HOH HOH A . FA 6 HOH 99 2099 2099 HOH HOH A . FA 6 HOH 100 2100 2100 HOH HOH A . FA 6 HOH 101 2101 2101 HOH HOH A . FA 6 HOH 102 2102 2102 HOH HOH A . FA 6 HOH 103 2103 2103 HOH HOH A . FA 6 HOH 104 2104 2104 HOH HOH A . FA 6 HOH 105 2105 2105 HOH HOH A . FA 6 HOH 106 2106 2106 HOH HOH A . FA 6 HOH 107 2107 2107 HOH HOH A . FA 6 HOH 108 2108 2108 HOH HOH A . FA 6 HOH 109 2109 2109 HOH HOH A . FA 6 HOH 110 2110 2110 HOH HOH A . FA 6 HOH 111 2111 2111 HOH HOH A . FA 6 HOH 112 2112 2112 HOH HOH A . FA 6 HOH 113 2113 2113 HOH HOH A . FA 6 HOH 114 2114 2114 HOH HOH A . FA 6 HOH 115 2115 2115 HOH HOH A . FA 6 HOH 116 2116 2116 HOH HOH A . FA 6 HOH 117 2117 2117 HOH HOH A . FA 6 HOH 118 2118 2118 HOH HOH A . FA 6 HOH 119 2119 2119 HOH HOH A . FA 6 HOH 120 2120 2120 HOH HOH A . FA 6 HOH 121 2121 2121 HOH HOH A . FA 6 HOH 122 2122 2122 HOH HOH A . FA 6 HOH 123 2123 2123 HOH HOH A . FA 6 HOH 124 2124 2124 HOH HOH A . FA 6 HOH 125 2125 2125 HOH HOH A . FA 6 HOH 126 2126 2126 HOH HOH A . FA 6 HOH 127 2127 2127 HOH HOH A . FA 6 HOH 128 2128 2128 HOH HOH A . FA 6 HOH 129 2129 2129 HOH HOH A . FA 6 HOH 130 2130 2130 HOH HOH A . FA 6 HOH 131 2131 2131 HOH HOH A . FA 6 HOH 132 2132 2132 HOH HOH A . FA 6 HOH 133 2133 2133 HOH HOH A . FA 6 HOH 134 2134 2134 HOH HOH A . FA 6 HOH 135 2135 2135 HOH HOH A . FA 6 HOH 136 2136 2136 HOH HOH A . FA 6 HOH 137 2137 2137 HOH HOH A . FA 6 HOH 138 2138 2138 HOH HOH A . FA 6 HOH 139 2139 2139 HOH HOH A . FA 6 HOH 140 2140 2140 HOH HOH A . FA 6 HOH 141 2141 2141 HOH HOH A . FA 6 HOH 142 2142 2142 HOH HOH A . FA 6 HOH 143 2143 2143 HOH HOH A . FA 6 HOH 144 2144 2144 HOH HOH A . FA 6 HOH 145 2145 2145 HOH HOH A . FA 6 HOH 146 2146 2146 HOH HOH A . FA 6 HOH 147 2147 2147 HOH HOH A . FA 6 HOH 148 2148 2148 HOH HOH A . FA 6 HOH 149 2149 2149 HOH HOH A . FA 6 HOH 150 2150 2150 HOH HOH A . FA 6 HOH 151 2151 2151 HOH HOH A . FA 6 HOH 152 2152 2152 HOH HOH A . FA 6 HOH 153 2153 2153 HOH HOH A . FA 6 HOH 154 2154 2154 HOH HOH A . FA 6 HOH 155 2155 2155 HOH HOH A . FA 6 HOH 156 2156 2156 HOH HOH A . FA 6 HOH 157 2157 2157 HOH HOH A . FA 6 HOH 158 2158 2158 HOH HOH A . FA 6 HOH 159 2159 2159 HOH HOH A . FA 6 HOH 160 2160 2160 HOH HOH A . FA 6 HOH 161 2161 2161 HOH HOH A . FA 6 HOH 162 2162 2162 HOH HOH A . FA 6 HOH 163 2163 2163 HOH HOH A . FA 6 HOH 164 2164 2164 HOH HOH A . FA 6 HOH 165 2165 2165 HOH HOH A . FA 6 HOH 166 2166 2166 HOH HOH A . FA 6 HOH 167 2167 2167 HOH HOH A . FA 6 HOH 168 2168 2168 HOH HOH A . FA 6 HOH 169 2169 2169 HOH HOH A . FA 6 HOH 170 2170 2170 HOH HOH A . FA 6 HOH 171 2171 2171 HOH HOH A . FA 6 HOH 172 2172 2172 HOH HOH A . FA 6 HOH 173 2173 2173 HOH HOH A . GA 6 HOH 1 2001 2001 HOH HOH B . GA 6 HOH 2 2002 2002 HOH HOH B . GA 6 HOH 3 2003 2003 HOH HOH B . GA 6 HOH 4 2004 2004 HOH HOH B . GA 6 HOH 5 2005 2005 HOH HOH B . GA 6 HOH 6 2006 2006 HOH HOH B . GA 6 HOH 7 2007 2007 HOH HOH B . GA 6 HOH 8 2008 2008 HOH HOH B . GA 6 HOH 9 2009 2009 HOH HOH B . GA 6 HOH 10 2010 2010 HOH HOH B . GA 6 HOH 11 2011 2011 HOH HOH B . GA 6 HOH 12 2012 2012 HOH HOH B . GA 6 HOH 13 2013 2013 HOH HOH B . GA 6 HOH 14 2014 2014 HOH HOH B . GA 6 HOH 15 2015 2015 HOH HOH B . GA 6 HOH 16 2016 2016 HOH HOH B . GA 6 HOH 17 2017 2017 HOH HOH B . GA 6 HOH 18 2018 2018 HOH HOH B . GA 6 HOH 19 2019 2019 HOH HOH B . GA 6 HOH 20 2020 2020 HOH HOH B . GA 6 HOH 21 2021 2021 HOH HOH B . GA 6 HOH 22 2022 2022 HOH HOH B . GA 6 HOH 23 2023 2023 HOH HOH B . GA 6 HOH 24 2024 2024 HOH HOH B . GA 6 HOH 25 2025 2025 HOH HOH B . GA 6 HOH 26 2026 2026 HOH HOH B . GA 6 HOH 27 2027 2027 HOH HOH B . GA 6 HOH 28 2028 2028 HOH HOH B . GA 6 HOH 29 2029 2029 HOH HOH B . GA 6 HOH 30 2030 2030 HOH HOH B . GA 6 HOH 31 2031 2031 HOH HOH B . GA 6 HOH 32 2032 2032 HOH HOH B . GA 6 HOH 33 2033 2033 HOH HOH B . GA 6 HOH 34 2034 2034 HOH HOH B . GA 6 HOH 35 2035 2035 HOH HOH B . GA 6 HOH 36 2036 2036 HOH HOH B . GA 6 HOH 37 2037 2037 HOH HOH B . GA 6 HOH 38 2038 2038 HOH HOH B . GA 6 HOH 39 2039 2039 HOH HOH B . GA 6 HOH 40 2040 2040 HOH HOH B . GA 6 HOH 41 2041 2041 HOH HOH B . GA 6 HOH 42 2042 2042 HOH HOH B . GA 6 HOH 43 2043 2043 HOH HOH B . GA 6 HOH 44 2044 2044 HOH HOH B . GA 6 HOH 45 2045 2045 HOH HOH B . GA 6 HOH 46 2046 2046 HOH HOH B . GA 6 HOH 47 2047 2047 HOH HOH B . GA 6 HOH 48 2048 2048 HOH HOH B . GA 6 HOH 49 2049 2049 HOH HOH B . GA 6 HOH 50 2050 2050 HOH HOH B . GA 6 HOH 51 2051 2051 HOH HOH B . GA 6 HOH 52 2052 2052 HOH HOH B . GA 6 HOH 53 2053 2053 HOH HOH B . GA 6 HOH 54 2054 2054 HOH HOH B . GA 6 HOH 55 2055 2055 HOH HOH B . GA 6 HOH 56 2056 2056 HOH HOH B . GA 6 HOH 57 2057 2057 HOH HOH B . GA 6 HOH 58 2058 2058 HOH HOH B . GA 6 HOH 59 2059 2059 HOH HOH B . GA 6 HOH 60 2060 2060 HOH HOH B . GA 6 HOH 61 2061 2061 HOH HOH B . GA 6 HOH 62 2062 2062 HOH HOH B . GA 6 HOH 63 2063 2063 HOH HOH B . GA 6 HOH 64 2064 2064 HOH HOH B . GA 6 HOH 65 2065 2065 HOH HOH B . GA 6 HOH 66 2066 2066 HOH HOH B . GA 6 HOH 67 2067 2067 HOH HOH B . GA 6 HOH 68 2068 2068 HOH HOH B . GA 6 HOH 69 2069 2069 HOH HOH B . GA 6 HOH 70 2070 2070 HOH HOH B . GA 6 HOH 71 2071 2071 HOH HOH B . GA 6 HOH 72 2072 2072 HOH HOH B . GA 6 HOH 73 2073 2073 HOH HOH B . GA 6 HOH 74 2074 2074 HOH HOH B . GA 6 HOH 75 2075 2075 HOH HOH B . GA 6 HOH 76 2076 2076 HOH HOH B . GA 6 HOH 77 2077 2077 HOH HOH B . GA 6 HOH 78 2078 2078 HOH HOH B . GA 6 HOH 79 2079 2079 HOH HOH B . GA 6 HOH 80 2080 2080 HOH HOH B . GA 6 HOH 81 2081 2081 HOH HOH B . GA 6 HOH 82 2082 2082 HOH HOH B . GA 6 HOH 83 2083 2083 HOH HOH B . GA 6 HOH 84 2084 2084 HOH HOH B . GA 6 HOH 85 2085 2085 HOH HOH B . GA 6 HOH 86 2086 2086 HOH HOH B . GA 6 HOH 87 2087 2087 HOH HOH B . GA 6 HOH 88 2088 2088 HOH HOH B . GA 6 HOH 89 2089 2089 HOH HOH B . GA 6 HOH 90 2090 2090 HOH HOH B . GA 6 HOH 91 2091 2091 HOH HOH B . GA 6 HOH 92 2092 2092 HOH HOH B . GA 6 HOH 93 2093 2093 HOH HOH B . GA 6 HOH 94 2094 2094 HOH HOH B . GA 6 HOH 95 2095 2095 HOH HOH B . GA 6 HOH 96 2096 2096 HOH HOH B . GA 6 HOH 97 2097 2097 HOH HOH B . GA 6 HOH 98 2098 2098 HOH HOH B . GA 6 HOH 99 2099 2099 HOH HOH B . GA 6 HOH 100 2100 2100 HOH HOH B . GA 6 HOH 101 2101 2101 HOH HOH B . GA 6 HOH 102 2102 2102 HOH HOH B . GA 6 HOH 103 2103 2103 HOH HOH B . GA 6 HOH 104 2104 2104 HOH HOH B . GA 6 HOH 105 2105 2105 HOH HOH B . GA 6 HOH 106 2106 2106 HOH HOH B . GA 6 HOH 107 2107 2107 HOH HOH B . GA 6 HOH 108 2108 2108 HOH HOH B . GA 6 HOH 109 2109 2109 HOH HOH B . GA 6 HOH 110 2110 2110 HOH HOH B . GA 6 HOH 111 2111 2111 HOH HOH B . GA 6 HOH 112 2112 2112 HOH HOH B . GA 6 HOH 113 2113 2113 HOH HOH B . GA 6 HOH 114 2114 2114 HOH HOH B . GA 6 HOH 115 2115 2115 HOH HOH B . GA 6 HOH 116 2116 2116 HOH HOH B . GA 6 HOH 117 2117 2117 HOH HOH B . GA 6 HOH 118 2118 2118 HOH HOH B . GA 6 HOH 119 2119 2119 HOH HOH B . GA 6 HOH 120 2120 2120 HOH HOH B . GA 6 HOH 121 2121 2121 HOH HOH B . GA 6 HOH 122 2122 2122 HOH HOH B . GA 6 HOH 123 2123 2123 HOH HOH B . GA 6 HOH 124 2124 2124 HOH HOH B . GA 6 HOH 125 2125 2125 HOH HOH B . GA 6 HOH 126 2126 2126 HOH HOH B . GA 6 HOH 127 2127 2127 HOH HOH B . GA 6 HOH 128 2128 2128 HOH HOH B . GA 6 HOH 129 2129 2129 HOH HOH B . GA 6 HOH 130 2130 2130 HOH HOH B . GA 6 HOH 131 2131 2131 HOH HOH B . GA 6 HOH 132 2132 2132 HOH HOH B . GA 6 HOH 133 2133 2133 HOH HOH B . GA 6 HOH 134 2134 2134 HOH HOH B . GA 6 HOH 135 2135 2135 HOH HOH B . GA 6 HOH 136 2136 2136 HOH HOH B . GA 6 HOH 137 2137 2137 HOH HOH B . GA 6 HOH 138 2138 2138 HOH HOH B . GA 6 HOH 139 2139 2139 HOH HOH B . GA 6 HOH 140 2140 2140 HOH HOH B . GA 6 HOH 141 2141 2141 HOH HOH B . GA 6 HOH 142 2142 2142 HOH HOH B . GA 6 HOH 143 2143 2143 HOH HOH B . GA 6 HOH 144 2144 2144 HOH HOH B . GA 6 HOH 145 2145 2145 HOH HOH B . GA 6 HOH 146 2146 2146 HOH HOH B . GA 6 HOH 147 2147 2147 HOH HOH B . GA 6 HOH 148 2148 2148 HOH HOH B . GA 6 HOH 149 2149 2149 HOH HOH B . GA 6 HOH 150 2150 2150 HOH HOH B . GA 6 HOH 151 2151 2151 HOH HOH B . GA 6 HOH 152 2152 2152 HOH HOH B . GA 6 HOH 153 2153 2153 HOH HOH B . GA 6 HOH 154 2154 2154 HOH HOH B . GA 6 HOH 155 2155 2155 HOH HOH B . GA 6 HOH 156 2156 2156 HOH HOH B . GA 6 HOH 157 2157 2157 HOH HOH B . GA 6 HOH 158 2158 2158 HOH HOH B . GA 6 HOH 159 2159 2159 HOH HOH B . GA 6 HOH 160 2160 2160 HOH HOH B . GA 6 HOH 161 2161 2161 HOH HOH B . GA 6 HOH 162 2162 2162 HOH HOH B . GA 6 HOH 163 2163 2163 HOH HOH B . GA 6 HOH 164 2164 2164 HOH HOH B . GA 6 HOH 165 2165 2165 HOH HOH B . GA 6 HOH 166 2166 2166 HOH HOH B . GA 6 HOH 167 2167 2167 HOH HOH B . GA 6 HOH 168 2168 2168 HOH HOH B . GA 6 HOH 169 2169 2169 HOH HOH B . GA 6 HOH 170 2170 2170 HOH HOH B . GA 6 HOH 171 2171 2171 HOH HOH B . GA 6 HOH 172 2172 2172 HOH HOH B . GA 6 HOH 173 2173 2173 HOH HOH B . GA 6 HOH 174 2174 2174 HOH HOH B . GA 6 HOH 175 2175 2175 HOH HOH B . GA 6 HOH 176 2176 2176 HOH HOH B . GA 6 HOH 177 2177 2177 HOH HOH B . GA 6 HOH 178 2178 2178 HOH HOH B . GA 6 HOH 179 2179 2179 HOH HOH B . GA 6 HOH 180 2180 2180 HOH HOH B . GA 6 HOH 181 2181 2181 HOH HOH B . GA 6 HOH 182 2182 2182 HOH HOH B . GA 6 HOH 183 2183 2183 HOH HOH B . GA 6 HOH 184 2184 2184 HOH HOH B . GA 6 HOH 185 2185 2185 HOH HOH B . GA 6 HOH 186 2186 2186 HOH HOH B . GA 6 HOH 187 2187 2187 HOH HOH B . GA 6 HOH 188 2188 2188 HOH HOH B . GA 6 HOH 189 2189 2189 HOH HOH B . GA 6 HOH 190 2190 2190 HOH HOH B . GA 6 HOH 191 2191 2191 HOH HOH B . GA 6 HOH 192 2192 2192 HOH HOH B . GA 6 HOH 193 2193 2193 HOH HOH B . GA 6 HOH 194 2194 2194 HOH HOH B . GA 6 HOH 195 2195 2195 HOH HOH B . GA 6 HOH 196 2196 2196 HOH HOH B . GA 6 HOH 197 2197 2197 HOH HOH B . HA 6 HOH 1 2001 2001 HOH HOH C . HA 6 HOH 2 2002 2002 HOH HOH C . HA 6 HOH 3 2003 2003 HOH HOH C . HA 6 HOH 4 2004 2004 HOH HOH C . HA 6 HOH 5 2005 2005 HOH HOH C . HA 6 HOH 6 2006 2006 HOH HOH C . HA 6 HOH 7 2007 2007 HOH HOH C . HA 6 HOH 8 2008 2008 HOH HOH C . HA 6 HOH 9 2009 2009 HOH HOH C . HA 6 HOH 10 2010 2010 HOH HOH C . HA 6 HOH 11 2011 2011 HOH HOH C . HA 6 HOH 12 2012 2012 HOH HOH C . HA 6 HOH 13 2013 2013 HOH HOH C . HA 6 HOH 14 2014 2014 HOH HOH C . HA 6 HOH 15 2015 2015 HOH HOH C . HA 6 HOH 16 2016 2016 HOH HOH C . HA 6 HOH 17 2017 2017 HOH HOH C . HA 6 HOH 18 2018 2018 HOH HOH C . HA 6 HOH 19 2019 2019 HOH HOH C . HA 6 HOH 20 2020 2020 HOH HOH C . HA 6 HOH 21 2021 2021 HOH HOH C . HA 6 HOH 22 2022 2022 HOH HOH C . HA 6 HOH 23 2023 2023 HOH HOH C . HA 6 HOH 24 2024 2024 HOH HOH C . HA 6 HOH 25 2025 2025 HOH HOH C . HA 6 HOH 26 2026 2026 HOH HOH C . HA 6 HOH 27 2027 2027 HOH HOH C . HA 6 HOH 28 2028 2028 HOH HOH C . HA 6 HOH 29 2029 2029 HOH HOH C . HA 6 HOH 30 2030 2030 HOH HOH C . HA 6 HOH 31 2031 2031 HOH HOH C . HA 6 HOH 32 2032 2032 HOH HOH C . HA 6 HOH 33 2033 2033 HOH HOH C . HA 6 HOH 34 2034 2034 HOH HOH C . HA 6 HOH 35 2035 2035 HOH HOH C . HA 6 HOH 36 2036 2036 HOH HOH C . HA 6 HOH 37 2037 2037 HOH HOH C . HA 6 HOH 38 2038 2038 HOH HOH C . HA 6 HOH 39 2039 2039 HOH HOH C . HA 6 HOH 40 2040 2040 HOH HOH C . HA 6 HOH 41 2041 2041 HOH HOH C . HA 6 HOH 42 2042 2042 HOH HOH C . HA 6 HOH 43 2043 2043 HOH HOH C . HA 6 HOH 44 2044 2044 HOH HOH C . HA 6 HOH 45 2045 2045 HOH HOH C . HA 6 HOH 46 2046 2046 HOH HOH C . HA 6 HOH 47 2047 2047 HOH HOH C . HA 6 HOH 48 2048 2048 HOH HOH C . HA 6 HOH 49 2049 2049 HOH HOH C . HA 6 HOH 50 2050 2050 HOH HOH C . HA 6 HOH 51 2051 2051 HOH HOH C . HA 6 HOH 52 2052 2052 HOH HOH C . HA 6 HOH 53 2053 2053 HOH HOH C . HA 6 HOH 54 2054 2054 HOH HOH C . HA 6 HOH 55 2055 2055 HOH HOH C . HA 6 HOH 56 2056 2056 HOH HOH C . HA 6 HOH 57 2057 2057 HOH HOH C . HA 6 HOH 58 2058 2058 HOH HOH C . HA 6 HOH 59 2059 2059 HOH HOH C . HA 6 HOH 60 2060 2060 HOH HOH C . HA 6 HOH 61 2061 2061 HOH HOH C . HA 6 HOH 62 2062 2062 HOH HOH C . HA 6 HOH 63 2063 2063 HOH HOH C . HA 6 HOH 64 2064 2064 HOH HOH C . HA 6 HOH 65 2065 2065 HOH HOH C . HA 6 HOH 66 2066 2066 HOH HOH C . HA 6 HOH 67 2067 2067 HOH HOH C . HA 6 HOH 68 2068 2068 HOH HOH C . HA 6 HOH 69 2069 2069 HOH HOH C . HA 6 HOH 70 2070 2070 HOH HOH C . HA 6 HOH 71 2071 2071 HOH HOH C . HA 6 HOH 72 2072 2072 HOH HOH C . HA 6 HOH 73 2073 2073 HOH HOH C . HA 6 HOH 74 2074 2074 HOH HOH C . HA 6 HOH 75 2075 2075 HOH HOH C . HA 6 HOH 76 2076 2076 HOH HOH C . HA 6 HOH 77 2077 2077 HOH HOH C . HA 6 HOH 78 2078 2078 HOH HOH C . HA 6 HOH 79 2079 2079 HOH HOH C . HA 6 HOH 80 2080 2080 HOH HOH C . HA 6 HOH 81 2081 2081 HOH HOH C . HA 6 HOH 82 2082 2082 HOH HOH C . HA 6 HOH 83 2083 2083 HOH HOH C . HA 6 HOH 84 2084 2084 HOH HOH C . HA 6 HOH 85 2085 2085 HOH HOH C . HA 6 HOH 86 2086 2086 HOH HOH C . HA 6 HOH 87 2087 2087 HOH HOH C . HA 6 HOH 88 2088 2088 HOH HOH C . HA 6 HOH 89 2089 2089 HOH HOH C . HA 6 HOH 90 2090 2090 HOH HOH C . HA 6 HOH 91 2091 2091 HOH HOH C . HA 6 HOH 92 2092 2092 HOH HOH C . HA 6 HOH 93 2093 2093 HOH HOH C . HA 6 HOH 94 2094 2094 HOH HOH C . HA 6 HOH 95 2095 2095 HOH HOH C . HA 6 HOH 96 2096 2096 HOH HOH C . HA 6 HOH 97 2097 2097 HOH HOH C . HA 6 HOH 98 2098 2098 HOH HOH C . HA 6 HOH 99 2099 2099 HOH HOH C . HA 6 HOH 100 2100 2100 HOH HOH C . HA 6 HOH 101 2101 2101 HOH HOH C . HA 6 HOH 102 2102 2102 HOH HOH C . HA 6 HOH 103 2103 2103 HOH HOH C . HA 6 HOH 104 2104 2104 HOH HOH C . HA 6 HOH 105 2105 2105 HOH HOH C . HA 6 HOH 106 2106 2106 HOH HOH C . HA 6 HOH 107 2107 2107 HOH HOH C . HA 6 HOH 108 2108 2108 HOH HOH C . HA 6 HOH 109 2109 2109 HOH HOH C . HA 6 HOH 110 2110 2110 HOH HOH C . HA 6 HOH 111 2111 2111 HOH HOH C . HA 6 HOH 112 2112 2112 HOH HOH C . HA 6 HOH 113 2113 2113 HOH HOH C . HA 6 HOH 114 2114 2114 HOH HOH C . HA 6 HOH 115 2115 2115 HOH HOH C . HA 6 HOH 116 2116 2116 HOH HOH C . HA 6 HOH 117 2117 2117 HOH HOH C . HA 6 HOH 118 2118 2118 HOH HOH C . HA 6 HOH 119 2119 2119 HOH HOH C . HA 6 HOH 120 2120 2120 HOH HOH C . HA 6 HOH 121 2121 2121 HOH HOH C . HA 6 HOH 122 2122 2122 HOH HOH C . HA 6 HOH 123 2123 2123 HOH HOH C . HA 6 HOH 124 2124 2124 HOH HOH C . HA 6 HOH 125 2125 2125 HOH HOH C . HA 6 HOH 126 2126 2126 HOH HOH C . HA 6 HOH 127 2127 2127 HOH HOH C . HA 6 HOH 128 2128 2128 HOH HOH C . HA 6 HOH 129 2129 2129 HOH HOH C . HA 6 HOH 130 2130 2130 HOH HOH C . HA 6 HOH 131 2131 2131 HOH HOH C . HA 6 HOH 132 2132 2132 HOH HOH C . HA 6 HOH 133 2133 2133 HOH HOH C . HA 6 HOH 134 2134 2134 HOH HOH C . HA 6 HOH 135 2135 2135 HOH HOH C . HA 6 HOH 136 2136 2136 HOH HOH C . HA 6 HOH 137 2137 2137 HOH HOH C . HA 6 HOH 138 2138 2138 HOH HOH C . HA 6 HOH 139 2139 2139 HOH HOH C . HA 6 HOH 140 2140 2140 HOH HOH C . HA 6 HOH 141 2141 2141 HOH HOH C . HA 6 HOH 142 2142 2142 HOH HOH C . HA 6 HOH 143 2143 2143 HOH HOH C . HA 6 HOH 144 2144 2144 HOH HOH C . HA 6 HOH 145 2145 2145 HOH HOH C . HA 6 HOH 146 2146 2146 HOH HOH C . HA 6 HOH 147 2147 2147 HOH HOH C . HA 6 HOH 148 2148 2148 HOH HOH C . HA 6 HOH 149 2149 2149 HOH HOH C . HA 6 HOH 150 2150 2150 HOH HOH C . HA 6 HOH 151 2151 2151 HOH HOH C . HA 6 HOH 152 2152 2152 HOH HOH C . HA 6 HOH 153 2153 2153 HOH HOH C . HA 6 HOH 154 2154 2154 HOH HOH C . HA 6 HOH 155 2155 2155 HOH HOH C . HA 6 HOH 156 2156 2156 HOH HOH C . HA 6 HOH 157 2157 2157 HOH HOH C . HA 6 HOH 158 2158 2158 HOH HOH C . HA 6 HOH 159 2159 2159 HOH HOH C . HA 6 HOH 160 2160 2160 HOH HOH C . HA 6 HOH 161 2161 2161 HOH HOH C . HA 6 HOH 162 2162 2162 HOH HOH C . HA 6 HOH 163 2163 2163 HOH HOH C . HA 6 HOH 164 2164 2164 HOH HOH C . HA 6 HOH 165 2165 2165 HOH HOH C . HA 6 HOH 166 2166 2166 HOH HOH C . HA 6 HOH 167 2167 2167 HOH HOH C . HA 6 HOH 168 2168 2168 HOH HOH C . HA 6 HOH 169 2169 2169 HOH HOH C . HA 6 HOH 170 2170 2170 HOH HOH C . HA 6 HOH 171 2171 2171 HOH HOH C . HA 6 HOH 172 2172 2172 HOH HOH C . HA 6 HOH 173 2173 2173 HOH HOH C . HA 6 HOH 174 2174 2174 HOH HOH C . HA 6 HOH 175 2175 2175 HOH HOH C . HA 6 HOH 176 2176 2176 HOH HOH C . HA 6 HOH 177 2177 2177 HOH HOH C . HA 6 HOH 178 2178 2178 HOH HOH C . HA 6 HOH 179 2179 2179 HOH HOH C . HA 6 HOH 180 2180 2180 HOH HOH C . HA 6 HOH 181 2181 2181 HOH HOH C . HA 6 HOH 182 2182 2182 HOH HOH C . HA 6 HOH 183 2183 2183 HOH HOH C . HA 6 HOH 184 2184 2184 HOH HOH C . HA 6 HOH 185 2185 2185 HOH HOH C . HA 6 HOH 186 2186 2186 HOH HOH C . HA 6 HOH 187 2187 2187 HOH HOH C . HA 6 HOH 188 2188 2188 HOH HOH C . HA 6 HOH 189 2189 2189 HOH HOH C . HA 6 HOH 190 2190 2190 HOH HOH C . HA 6 HOH 191 2191 2191 HOH HOH C . HA 6 HOH 192 2192 2192 HOH HOH C . HA 6 HOH 193 2193 2193 HOH HOH C . HA 6 HOH 194 2194 2194 HOH HOH C . HA 6 HOH 195 2195 2195 HOH HOH C . HA 6 HOH 196 2196 2196 HOH HOH C . HA 6 HOH 197 2197 2197 HOH HOH C . HA 6 HOH 198 2198 2198 HOH HOH C . HA 6 HOH 199 2199 2199 HOH HOH C . HA 6 HOH 200 2200 2200 HOH HOH C . HA 6 HOH 201 2201 2201 HOH HOH C . HA 6 HOH 202 2202 2202 HOH HOH C . HA 6 HOH 203 2203 2203 HOH HOH C . HA 6 HOH 204 2204 2204 HOH HOH C . HA 6 HOH 205 2205 2205 HOH HOH C . HA 6 HOH 206 2206 2206 HOH HOH C . HA 6 HOH 207 2207 2207 HOH HOH C . HA 6 HOH 208 2208 2208 HOH HOH C . HA 6 HOH 209 2209 2209 HOH HOH C . HA 6 HOH 210 2210 2210 HOH HOH C . HA 6 HOH 211 2211 2211 HOH HOH C . HA 6 HOH 212 2212 2212 HOH HOH C . HA 6 HOH 213 2213 2213 HOH HOH C . HA 6 HOH 214 2214 2214 HOH HOH C . HA 6 HOH 215 2215 2215 HOH HOH C . HA 6 HOH 216 2216 2216 HOH HOH C . HA 6 HOH 217 2217 2217 HOH HOH C . HA 6 HOH 218 2218 2218 HOH HOH C . HA 6 HOH 219 2219 2219 HOH HOH C . HA 6 HOH 220 2220 2220 HOH HOH C . HA 6 HOH 221 2221 2221 HOH HOH C . HA 6 HOH 222 2222 2222 HOH HOH C . HA 6 HOH 223 2223 2223 HOH HOH C . HA 6 HOH 224 2224 2224 HOH HOH C . HA 6 HOH 225 2225 2225 HOH HOH C . HA 6 HOH 226 2226 2226 HOH HOH C . HA 6 HOH 227 2227 2227 HOH HOH C . HA 6 HOH 228 2228 2228 HOH HOH C . HA 6 HOH 229 2229 2229 HOH HOH C . HA 6 HOH 230 2230 2230 HOH HOH C . HA 6 HOH 231 2231 2231 HOH HOH C . HA 6 HOH 232 2232 2232 HOH HOH C . HA 6 HOH 233 2233 2233 HOH HOH C . HA 6 HOH 234 2234 2234 HOH HOH C . HA 6 HOH 235 2235 2235 HOH HOH C . HA 6 HOH 236 2236 2236 HOH HOH C . HA 6 HOH 237 2237 2237 HOH HOH C . HA 6 HOH 238 2238 2238 HOH HOH C . HA 6 HOH 239 2239 2239 HOH HOH C . HA 6 HOH 240 2240 2240 HOH HOH C . HA 6 HOH 241 2241 2241 HOH HOH C . HA 6 HOH 242 2242 2242 HOH HOH C . HA 6 HOH 243 2243 2243 HOH HOH C . HA 6 HOH 244 2244 2244 HOH HOH C . HA 6 HOH 245 2245 2245 HOH HOH C . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 19 A ASN 20 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 68 A ASN 69 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 76 A ASN 77 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 167 A ASN 168 ? ASN 'GLYCOSYLATION SITE' 5 A ASN 196 A ASN 197 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 19 B ASN 20 ? ASN 'GLYCOSYLATION SITE' 7 B ASN 68 B ASN 69 ? ASN 'GLYCOSYLATION SITE' 8 B ASN 76 B ASN 77 ? ASN 'GLYCOSYLATION SITE' 9 B ASN 167 B ASN 168 ? ASN 'GLYCOSYLATION SITE' 10 B ASN 196 B ASN 197 ? ASN 'GLYCOSYLATION SITE' 11 C ASN 19 C ASN 20 ? ASN 'GLYCOSYLATION SITE' 12 C ASN 68 C ASN 69 ? ASN 'GLYCOSYLATION SITE' 13 C ASN 76 C ASN 77 ? ASN 'GLYCOSYLATION SITE' 14 C ASN 167 C ASN 168 ? ASN 'GLYCOSYLATION SITE' 15 C ASN 196 C ASN 197 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA monomeric 1 2 author_and_software_defined_assembly PISA monomeric 1 3 author_and_software_defined_assembly PISA monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,D,E,F,G,H,I,J,K,FA 2 1 B,L,M,N,O,P,Q,R,S,T,GA 3 1 C,U,V,W,X,Y,Z,AA,BA,CA,DA,EA,HA # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # _pdbx_struct_special_symmetry.id 1 _pdbx_struct_special_symmetry.PDB_model_num 1 _pdbx_struct_special_symmetry.auth_asym_id C _pdbx_struct_special_symmetry.auth_comp_id HOH _pdbx_struct_special_symmetry.auth_seq_id 2068 _pdbx_struct_special_symmetry.PDB_ins_code ? _pdbx_struct_special_symmetry.label_asym_id HA _pdbx_struct_special_symmetry.label_comp_id HOH _pdbx_struct_special_symmetry.label_seq_id . # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2013-05-01 2 'Structure model' 1 1 2013-05-08 3 'Structure model' 1 2 2013-05-29 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Database references' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal BUSTER refinement 2.11.2 ? 1 MOSFLM 'data reduction' . ? 2 SCALA 'data scaling' . ? 3 autoSHARP phasing . ? 4 # _pdbx_entry_details.entry_id 4BFE _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? _pdbx_entry_details.nonpolymer_details ? _pdbx_entry_details.sequence_details ;NUMBERING IN THE PDB IS BASED ON THE START OF THE MATURE SEQUENCE, AS DETERMINED BY N-TERMINAL SEQUENCING ON THE HOMOLOGUE MCD200R. ; # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 28 ? ? 75.78 -7.06 2 1 ASP A 85 ? ? -141.13 -88.97 3 1 PRO A 147 ? ? -69.10 -178.38 4 1 GLN A 181 ? ? -37.93 117.54 5 1 ASP B 28 ? ? 73.55 -9.11 6 1 ASP B 85 ? ? -140.82 -88.15 7 1 ASP C 28 ? ? 77.50 -8.55 8 1 ASP C 85 ? ? -140.43 -88.85 9 1 GLN C 181 ? ? -42.72 108.46 # loop_ _pdbx_distant_solvent_atoms.id _pdbx_distant_solvent_atoms.PDB_model_num _pdbx_distant_solvent_atoms.auth_atom_id _pdbx_distant_solvent_atoms.label_alt_id _pdbx_distant_solvent_atoms.auth_asym_id _pdbx_distant_solvent_atoms.auth_comp_id _pdbx_distant_solvent_atoms.auth_seq_id _pdbx_distant_solvent_atoms.PDB_ins_code _pdbx_distant_solvent_atoms.neighbor_macromolecule_distance _pdbx_distant_solvent_atoms.neighbor_ligand_distance 1 1 O ? B HOH 2091 ? 6.45 . 2 1 O ? C HOH 2226 ? 8.43 . 3 1 O ? C HOH 2227 ? 9.17 . 4 1 O ? C HOH 2228 ? . 6.71 5 1 O ? C HOH 2229 ? . 6.33 6 1 O ? C HOH 2232 ? 6.53 . 7 1 O ? C HOH 2233 ? 6.15 . 8 1 O ? C HOH 2234 ? . 6.55 9 1 O ? C HOH 2235 ? 8.00 . 10 1 O ? C HOH 2236 ? 8.71 . 11 1 O ? C HOH 2237 ? . 7.06 12 1 O ? C HOH 2238 ? . 7.89 13 1 O ? C HOH 2239 ? . 7.56 14 1 O ? C HOH 2240 ? 7.66 . 15 1 O ? C HOH 2241 ? 8.80 . 16 1 O ? C HOH 2242 ? 7.72 . 17 1 O ? C HOH 2243 ? . 8.49 18 1 O ? C HOH 2244 ? . 7.51 19 1 O ? C HOH 2245 ? 5.89 . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A THR 2 ? A THR 1 2 1 Y 1 A ASP 3 ? A ASP 2 3 1 Y 1 A GLU 4 ? A GLU 3 4 1 Y 1 A ASN 5 ? A ASN 4 5 1 Y 1 A GLN 6 ? A GLN 5 6 1 Y 1 A THR 7 ? A THR 6 7 1 Y 1 A ILE 8 ? A ILE 7 8 1 Y 1 A GLN 9 ? A GLN 8 9 1 Y 1 A ASN 10 ? A ASN 9 10 1 Y 1 A ASP 11 ? A ASP 10 11 1 Y 1 A SER 12 ? A SER 11 12 1 Y 1 A SER 13 ? A SER 12 13 1 Y 1 A SER 14 ? A SER 13 14 1 Y 1 A SER 15 ? A SER 14 15 1 Y 1 A LEU 16 ? A LEU 15 16 1 Y 1 A THR 17 ? A THR 16 17 1 Y 1 A GLN 206 ? A GLN 205 18 1 Y 1 A GLY 207 ? A GLY 206 19 1 Y 1 A THR 208 ? A THR 207 20 1 Y 1 A MET 209 ? A MET 208 21 1 Y 1 A THR 210 ? A THR 209 22 1 Y 1 A THR 211 ? A THR 210 23 1 Y 1 A PRO 212 ? A PRO 211 24 1 Y 1 A ARG 213 ? A ARG 212 25 1 Y 1 A SER 214 ? A SER 213 26 1 Y 1 A THR 215 ? A THR 214 27 1 Y 1 A ARG 216 ? A ARG 215 28 1 Y 1 A HIS 217 ? A HIS 216 29 1 Y 1 A HIS 218 ? A HIS 217 30 1 Y 1 A HIS 219 ? A HIS 218 31 1 Y 1 A HIS 220 ? A HIS 219 32 1 Y 1 A HIS 221 ? A HIS 220 33 1 Y 1 A HIS 222 ? A HIS 221 34 1 Y 1 B THR 2 ? B THR 1 35 1 Y 1 B ASP 3 ? B ASP 2 36 1 Y 1 B GLU 4 ? B GLU 3 37 1 Y 1 B ASN 5 ? B ASN 4 38 1 Y 1 B GLN 6 ? B GLN 5 39 1 Y 1 B THR 7 ? B THR 6 40 1 Y 1 B ILE 8 ? B ILE 7 41 1 Y 1 B GLN 9 ? B GLN 8 42 1 Y 1 B ASN 10 ? B ASN 9 43 1 Y 1 B ASP 11 ? B ASP 10 44 1 Y 1 B SER 12 ? B SER 11 45 1 Y 1 B SER 13 ? B SER 12 46 1 Y 1 B SER 14 ? B SER 13 47 1 Y 1 B SER 15 ? B SER 14 48 1 Y 1 B LEU 16 ? B LEU 15 49 1 Y 1 B THR 17 ? B THR 16 50 1 Y 1 B GLN 206 ? B GLN 205 51 1 Y 1 B GLY 207 ? B GLY 206 52 1 Y 1 B THR 208 ? B THR 207 53 1 Y 1 B MET 209 ? B MET 208 54 1 Y 1 B THR 210 ? B THR 209 55 1 Y 1 B THR 211 ? B THR 210 56 1 Y 1 B PRO 212 ? B PRO 211 57 1 Y 1 B ARG 213 ? B ARG 212 58 1 Y 1 B SER 214 ? B SER 213 59 1 Y 1 B THR 215 ? B THR 214 60 1 Y 1 B ARG 216 ? B ARG 215 61 1 Y 1 B HIS 217 ? B HIS 216 62 1 Y 1 B HIS 218 ? B HIS 217 63 1 Y 1 B HIS 219 ? B HIS 218 64 1 Y 1 B HIS 220 ? B HIS 219 65 1 Y 1 B HIS 221 ? B HIS 220 66 1 Y 1 B HIS 222 ? B HIS 221 67 1 Y 1 C THR 2 ? C THR 1 68 1 Y 1 C ASP 3 ? C ASP 2 69 1 Y 1 C GLU 4 ? C GLU 3 70 1 Y 1 C ASN 5 ? C ASN 4 71 1 Y 1 C GLN 6 ? C GLN 5 72 1 Y 1 C THR 7 ? C THR 6 73 1 Y 1 C ILE 8 ? C ILE 7 74 1 Y 1 C GLN 9 ? C GLN 8 75 1 Y 1 C ASN 10 ? C ASN 9 76 1 Y 1 C ASP 11 ? C ASP 10 77 1 Y 1 C SER 12 ? C SER 11 78 1 Y 1 C SER 13 ? C SER 12 79 1 Y 1 C SER 14 ? C SER 13 80 1 Y 1 C SER 15 ? C SER 14 81 1 Y 1 C LEU 16 ? C LEU 15 82 1 Y 1 C THR 17 ? C THR 16 83 1 Y 1 C GLN 18 ? C GLN 17 84 1 Y 1 C GLN 206 ? C GLN 205 85 1 Y 1 C GLY 207 ? C GLY 206 86 1 Y 1 C THR 208 ? C THR 207 87 1 Y 1 C MET 209 ? C MET 208 88 1 Y 1 C THR 210 ? C THR 209 89 1 Y 1 C THR 211 ? C THR 210 90 1 Y 1 C PRO 212 ? C PRO 211 91 1 Y 1 C ARG 213 ? C ARG 212 92 1 Y 1 C SER 214 ? C SER 213 93 1 Y 1 C THR 215 ? C THR 214 94 1 Y 1 C ARG 216 ? C ARG 215 95 1 Y 1 C HIS 217 ? C HIS 216 96 1 Y 1 C HIS 218 ? C HIS 217 97 1 Y 1 C HIS 219 ? C HIS 218 98 1 Y 1 C HIS 220 ? C HIS 219 99 1 Y 1 C HIS 221 ? C HIS 220 100 1 Y 1 C HIS 222 ? C HIS 221 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 CYSTEINE CYS 4 'SULFATE ION' SO4 5 GLYCEROL GOL 6 water HOH #